ONTOLOGY	ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	zScore	pvalue	p.adjust	qvalue	geneID	Count
BP	GO:0030198	extracellular matrix organization	39/232	339/18986	0.115044247787611	9.41478486420507	17.387643135704	1.02955380214315e-26	1.83416028521119e-23	9.16131952807221e-24	MMP2/MMP1/PDGFRA/DDR1/ITGB1/CPB2/MMP9/MMP8/MMP13/MMP3/ADAMTS4/ADAMTS1/MMP14/CYP1B1/LAMA1/COL1A2/COL1A1/COL2A1/COL3A1/COL4A1/COL5A1/COL6A1/COL11A1/COL18A1/COL27A1/COL4A2/COL5A2/COL11A2/COL4A3/COL4A4/COL4A5/COL4A6/LAMB1/LAMB2/ADAMTS5/TGFBR1/B4GALT1/TNF/PLG	39
BP	GO:0043062	extracellular structure organization	39/232	340/18986	0.114705882352941	9.38709432048681	17.356433273476	1.15124441508713e-26	1.83416028521119e-23	9.16131952807221e-24	MMP2/MMP1/PDGFRA/DDR1/ITGB1/CPB2/MMP9/MMP8/MMP13/MMP3/ADAMTS4/ADAMTS1/MMP14/CYP1B1/LAMA1/COL1A2/COL1A1/COL2A1/COL3A1/COL4A1/COL5A1/COL6A1/COL11A1/COL18A1/COL27A1/COL4A2/COL5A2/COL11A2/COL4A3/COL4A4/COL4A5/COL4A6/LAMB1/LAMB2/ADAMTS5/TGFBR1/B4GALT1/TNF/PLG	39
BP	GO:0045229	external encapsulating structure organization	39/232	341/18986	0.114369501466276	9.35956618464961	17.3253522623681	1.2868290120752e-26	1.83416028521119e-23	9.16131952807221e-24	MMP2/MMP1/PDGFRA/DDR1/ITGB1/CPB2/MMP9/MMP8/MMP13/MMP3/ADAMTS4/ADAMTS1/MMP14/CYP1B1/LAMA1/COL1A2/COL1A1/COL2A1/COL3A1/COL4A1/COL5A1/COL6A1/COL11A1/COL18A1/COL27A1/COL4A2/COL5A2/COL11A2/COL4A3/COL4A4/COL4A5/COL4A6/LAMB1/LAMB2/ADAMTS5/TGFBR1/B4GALT1/TNF/PLG	39
BP	GO:0042060	wound healing	42/232	444/18986	0.0945945945945946	7.74126281453868	15.9866251877085	2.49108464123819e-25	2.66296948148362e-22	1.33010808870323e-22	VEGFA/KDR/PRKCA/RHOA/PDGFRA/MYH9/DDR1/ITGB1/CPB2/PRKCD/PRKCQ/PLAU/PLAUR/EPHB2/FLNA/GLA/F2/FGA/FGB/FGG/COL3A1/COL5A1/HTR2A/RAF1/PPIA/PLAT/F13A1/TGFBR1/PDGFA/B4GALT1/PF4/INS/CLEC7A/TNF/PPP3CA/PLG/NPR2/HNF4A/ALOX5/ALOX15/SLC6A4/PLEC	42
BP	GO:0009410	response to xenobiotic stimulus	42/232	451/18986	0.0931263858093126	7.62111017661901	15.8279666962843	4.62556829650952e-25	3.95578600717494e-22	1.97584801549849e-22	NTRK1/MMP2/SNCA/PDE4A/PDE3A/PDE4B/CPB2/MAOB/RORA/CHUK/ATR/CDK1/CDKN1B/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2R1/CYP2S1/TP53/MDM2/ABCA1/BPHL/COL1A1/COL6A1/COL18A1/HTR2A/BRAF/HSPA8/LIPA/TNF/HNF4A/TRPA1/AHR/BCL2/PTGS2/SRD5A1/SLC6A4/SLC6A3	42
BP	GO:0043410	positive regulation of MAPK cascade	36/232	472/18986	0.076271186440678	6.24174459380479	12.8262311663552	1.16656846920168e-18	8.31374462384396e-16	4.15257442808808e-16	VEGFA/KDR/NTRK1/NTRK2/ITGA1/PDE5A/PDE6H/PDE8B/PRKCA/PDGFRB/PDGFRA/SHC1/ICAM1/INHBA/PLA2G2A/XIAP/PLA2G5/IGF2/FGA/FGB/FGG/NTRK3/HTR2A/RAF1/BRAF/PPIA/PDGFA/NRP1/FLT1/INS/TNF/HAVCR2/PRKCZ/HGF/AR/ALOX15	36
BP	GO:0035987	endodermal cell differentiation	15/232	52/18986	0.288461538461538	23.6065981432361	18.1559106624801	3.85106952015018e-17	2.35245332402317e-14	1.17501053479469e-14	MMP2/MYH9/ITGB2/INHBA/MMP9/MMP8/MMP14/COL5A1/COL6A1/COL11A1/COL4A2/COL5A2/LAMA3/LAMB1/LAMB3	15
BP	GO:0007596	blood coagulation	25/232	234/18986	0.106837606837607	8.74318449749484	13.255804068666	1.26452844703113e-16	6.7589045493814e-14	3.37595818292917e-14	PRKCA/PDGFRA/MYH9/CPB2/PRKCD/PRKCQ/PLAU/PLAUR/EPHB2/FLNA/GLA/F2/FGA/FGB/FGG/COL3A1/HTR2A/PPIA/PLAT/F13A1/PDGFA/PF4/PLG/HNF4A/SLC6A4	25
BP	GO:0007599	hemostasis	25/232	241/18986	0.103734439834025	8.48923308055516	13.013840606822	2.55284834204802e-16	1.09159795105973e-13	5.45234661685836e-14	PRKCA/PDGFRA/MYH9/CPB2/PRKCD/PRKCQ/PLAU/PLAUR/EPHB2/FLNA/GLA/F2/FGA/FGB/FGG/COL3A1/HTR2A/PPIA/PLAT/F13A1/PDGFA/PF4/PLG/HNF4A/SLC6A4	25
BP	GO:0050817	coagulation	25/232	241/18986	0.103734439834025	8.48923308055516	13.013840606822	2.55284834204802e-16	1.09159795105973e-13	5.45234661685836e-14	PRKCA/PDGFRA/MYH9/CPB2/PRKCD/PRKCQ/PLAU/PLAUR/EPHB2/FLNA/GLA/F2/FGA/FGB/FGG/COL3A1/HTR2A/PPIA/PLAT/F13A1/PDGFA/PF4/PLG/HNF4A/SLC6A4	25
BP	GO:0070374	positive regulation of ERK1 and ERK2 cascade	23/232	197/18986	0.116751269035533	9.55448100822685	13.4238559667869	3.11678844172558e-16	1.21158067061987e-13	6.0516399504892e-14	VEGFA/KDR/NTRK1/PDE8B/PRKCA/PDGFRB/PDGFRA/SHC1/ICAM1/INHBA/PLA2G2A/PLA2G5/FGA/FGB/FGG/HTR2A/BRAF/PDGFA/NRP1/TNF/HAVCR2/PRKCZ/ALOX15	23
BP	GO:0050878	regulation of body fluid levels	30/232	381/18986	0.078740157480315	6.44379581862612	11.938556406445	4.72219996457843e-16	1.68267725404478e-13	8.40468748081546e-14	VEGFA/PRKCA/PDGFRA/MYH9/DDR1/CPB2/PRKCD/PRKCQ/PLAU/PLAUR/EPHB2/FLNA/GLA/F2/FGA/FGB/FGG/COL3A1/HTR2A/PPIA/PLAT/F13A1/PDGFA/PF4/PPP3CA/PLG/NPR3/HNF4A/SLC6A4/SLC6A3	30
BP	GO:0001706	endoderm formation	15/232	61/18986	0.245901639344262	20.1236574335783	16.6387335181299	5.50114803525188e-16	1.80945453836439e-13	9.03791851297657e-14	MMP2/MYH9/ITGB2/INHBA/MMP9/MMP8/MMP14/COL5A1/COL6A1/COL11A1/COL4A2/COL5A2/LAMA3/LAMB1/LAMB3	15
BP	GO:0043434	response to peptide hormone	32/232	446/18986	0.0717488789237668	5.87165610020102	11.5795457997488	6.64142104363952e-16	2.02847974161447e-13	1.01319122537929e-13	NR4A2/PDE3B/CCNA2/PRKCA/NR4A3/SHC1/EGR1/INHBA/EDNRA/PRKCD/PRKCQ/CHUK/CDKN1B/CYP1B1/AHSG/MDM2/IGF2/NR4A1/LTA4H/COL1A1/COL3A1/COL6A1/RAF1/BRAF/INS/PPP3CA/NPR2/HNF4A/PRKCZ/CA2/PTGS2/SRD5A1	32
BP	GO:0031589	cell-substrate adhesion	29/232	361/18986	0.0803324099722992	6.57409972299169	11.8927566314491	8.91361751720561e-16	2.54097523357141e-13	1.26917403104633e-13	VEGFA/KDR/ITGA1/RHOA/APOA1/DDR1/ITGB1/ITGAL/ITGB2/PLAU/ITGB7/MMP14/CDKN2A/EPHB3/EPHB1/FLNA/FGA/FGB/FGG/COL1A1/COL3A1/LAMA5/LAMB1/BRAF/NRP1/PLG/PRKCZ/BCL2/ALOX15	29
BP	GO:0001101	response to acid chemical	20/232	144/18986	0.138888888888889	11.3661398467433	13.8879181141722	9.60359293478854e-16	2.56656021182224e-13	1.28195329372934e-13	VEGFA/NTRK1/NTRK2/MMP2/PDGFRA/CHUK/MMP3/CDKN1B/COL1A2/COL1A1/COL3A1/COL4A1/COL6A1/COL18A1/COL5A2/COL4A6/TNF/BCL2L1/PTGS2/PLEC	20
BP	GO:0070371	ERK1 and ERK2 cascade	27/232	319/18986	0.0846394984326019	6.92657550535077	11.8731030416879	2.58400630525839e-15	6.49953585957933e-13	3.24640792159088e-13	VEGFA/KDR/NTRK1/HMGCR/PDE8B/PRKCA/PDGFRB/PDGFRA/SHC1/ICAM1/INHBA/PLA2G2A/CDK1/PLA2G5/EPHB2/EPHB1/FGA/FGB/FGG/HTR2A/BRAF/PDGFA/NRP1/TNF/HAVCR2/PRKCZ/ALOX15	27
BP	GO:0070372	regulation of ERK1 and ERK2 cascade	26/232	296/18986	0.0878378378378378	7.18831547064306	11.9348231337866	3.60142195008566e-15	8.5553779214257e-13	4.27326616182678e-13	VEGFA/KDR/NTRK1/HMGCR/PDE8B/PRKCA/PDGFRB/PDGFRA/SHC1/ICAM1/INHBA/PLA2G2A/PLA2G5/EPHB2/EPHB1/FGA/FGB/FGG/HTR2A/BRAF/PDGFA/NRP1/TNF/HAVCR2/PRKCZ/ALOX15	26
BP	GO:1903034	regulation of response to wounding	21/232	181/18986	0.116022099447514	9.49480853495904	12.7719894352291	7.29563966659154e-15	1.64190290601818e-12	8.20102652826273e-13	PDGFRA/ITGB1/CPB2/PRKCD/PLAU/PLAUR/EPHB2/FLNA/F2/FGA/FGB/FGG/BRAF/PLAT/PDGFA/PF4/GRN/CLEC7A/TNF/PLG/ALOX5	21
BP	GO:0045785	positive regulation of cell adhesion	32/232	499/18986	0.064128256513026	5.24801326791514	10.6956024995649	1.56845759485259e-14	3.35336233779484e-12	1.67494761050311e-12	VEGFA/KDR/PRKCA/NR4A3/RHOA/APOA1/ITGB2/PRKCQ/ATM/SMARCA4/PLAUR/FLNA/BRD4/IGF2/LAMA1/FGA/FGB/FGG/IL12B/LAMB1/LAMB2/HTR2A/BRAF/KLRK1/NRP1/HLA-A/TNF/PPP3CA/HAVCR2/PRKCZ/ALOX5/ALOX15	32
BP	GO:0032102	negative regulation of response to external stimulus	30/232	437/18986	0.068649885583524	5.61804624003788	10.8627824601984	1.86968799573345e-14	3.80704089036012e-12	1.90155235255297e-12	APOA1/PDGFRA/CPB2/PRKCD/RORA/PLAU/PLAUR/PLA2G10/LTF/F2/FGA/FGB/FGG/IL12B/PLAT/PDGFA/PF4/KLRK1/MICA/NRP1/HLA-A/GRN/INS/TNF/PLG/HAVCR2/HGF/AHR/ALOX5/SLC6A3	30
BP	GO:0006935	chemotaxis	31/232	472/18986	0.0656779661016949	5.37483562244302	10.7049574820145	2.20061669101309e-14	4.27578480569725e-12	2.13568198777995e-12	VEGFA/KDR/MMP2/ITGA1/PDE4B/RHOA/APOA1/PDGFRB/PDGFRA/ITGB2/PRKCD/PRKCQ/PLAU/NRP2/CXCL8/PLAUR/EPHB1/IL17RA/NR4A1/NTRK3/PPIA/CXCR1/PDGFA/PF4/KLRK1/NRP1/FLT1/CXCR2/HGF/ALOX5/PLEC	31
BP	GO:0030195	negative regulation of blood coagulation	13/232	50/18986	0.26	21.2774137931035	15.9681932829588	2.29988425002425e-14	4.27578480569725e-12	2.13568198777995e-12	PDGFRA/CPB2/PRKCD/PLAU/PLAUR/F2/FGA/FGB/FGG/PLAT/PDGFA/PF4/PLG	13
BP	GO:0042330	taxis	31/232	474/18986	0.0654008438818565	5.35215699112469	10.672579295779	2.46734811409583e-14	4.39599188994741e-12	2.19572338750019e-12	VEGFA/KDR/MMP2/ITGA1/PDE4B/RHOA/APOA1/PDGFRB/PDGFRA/ITGB2/PRKCD/PRKCQ/PLAU/NRP2/CXCL8/PLAUR/EPHB1/IL17RA/NR4A1/NTRK3/PPIA/CXCR1/PDGFA/PF4/KLRK1/NRP1/FLT1/CXCR2/HGF/ALOX5/PLEC	31
BP	GO:0061045	negative regulation of wound healing	15/232	78/18986	0.192307692307692	15.7377320954907	14.5063282164201	2.83575069200309e-14	4.85026798360209e-12	2.42262659118917e-12	PDGFRA/CPB2/PRKCD/PLAU/PLAUR/F2/FGA/FGB/FGG/PLAT/PDGFA/PF4/TNF/PLG/ALOX5	15
BP	GO:1900047	negative regulation of hemostasis	13/232	51/18986	0.254901960784314	20.8602096010818	15.7956898713162	3.05361255586633e-14	5.02201818803248e-12	2.50841290520356e-12	PDGFRA/CPB2/PRKCD/PLAU/PLAUR/F2/FGA/FGB/FGG/PLAT/PDGFA/PF4/PLG	13
BP	GO:2001234	negative regulation of apoptotic signaling pathway	23/232	244/18986	0.0942622950819672	7.71406868287168	11.7401883215095	3.3756549357119e-14	5.34603722411262e-12	2.6702549179569e-12	NR4A2/ICAM1/MMP9/HSPA1A/PLAUR/LMNA/MDM2/FGA/FGB/FGG/COL2A1/RAF1/PPIA/TGFBR1/PF4/NRP1/INS/TNF/HGF/AR/BCL2L1/BCL2/PTGS2	23
BP	GO:0048732	gland development	30/232	450/18986	0.0666666666666667	5.45574712643678	10.6394975655196	4.04857143411943e-14	6.18274694724809e-12	3.08817723301816e-12	VEGFA/MMP2/APOA1/PDGFRA/DDR1/CPB2/PSAP/EDNRA/ESR1/THRA/ATM/CDKN1B/CYP1A1/CYP1B1/EPHB3/IGF2/LAMA1/LAMA5/RAF1/BRAF/TGFBR1/PDGFA/NRP1/LIPA/TNF/HGF/AR/BCL2/SRD5A1/SLC6A3	30
BP	GO:0050819	negative regulation of coagulation	13/232	54/18986	0.240740740740741	19.7013090676884	15.3063971283181	6.87927770946301e-14	1.01433763743668e-11	5.06644445462811e-12	PDGFRA/CPB2/PRKCD/PLAU/PLAUR/F2/FGA/FGB/FGG/PLAT/PDGFA/PF4/PLG	13
BP	GO:0071229	cellular response to acid chemical	16/232	100/18986	0.16	13.0937931034483	13.4863640632545	7.97202535831194e-14	1.13627934773806e-11	5.67552261474208e-12	VEGFA/NTRK2/MMP2/PDGFRA/MMP3/COL1A2/COL1A1/COL3A1/COL4A1/COL6A1/COL5A2/COL4A6/TNF/BCL2L1/PTGS2/PLEC	16
BP	GO:0030193	regulation of blood coagulation	14/232	69/18986	0.202898550724638	16.6044477761119	14.4427254266601	9.52269288373639e-14	1.3135172506728e-11	6.56079587813281e-12	PDGFRA/CPB2/PRKCD/PLAU/PLAUR/EPHB2/F2/FGA/FGB/FGG/PLAT/PDGFA/PF4/PLG	14
BP	GO:0061041	regulation of wound healing	18/232	140/18986	0.128571428571429	10.5217980295566	12.5769613717325	1.08345401387093e-13	1.42472149932831e-11	7.11624223853367e-12	PDGFRA/ITGB1/CPB2/PRKCD/PLAU/PLAUR/EPHB2/F2/FGA/FGB/FGG/PLAT/PDGFA/PF4/CLEC7A/TNF/PLG/ALOX5	18
BP	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	16/232	102/18986	0.156862745098039	12.8370520622042	13.3321129726737	1.09952781753588e-13	1.42472149932831e-11	7.11624223853367e-12	ICAM1/HSPA1A/LMNA/FGA/FGB/FGG/COL2A1/RAF1/TGFBR1/PF4/NRP1/TNF/HGF/AR/BCL2L1/BCL2	16
BP	GO:1900046	regulation of hemostasis	14/232	71/18986	0.197183098591549	16.1367168528412	14.21215796694	1.45106939304633e-13	1.82493315431356e-11	9.11523157427556e-12	PDGFRA/CPB2/PRKCD/PLAU/PLAUR/EPHB2/F2/FGA/FGB/FGG/PLAT/PDGFA/PF4/PLG	14
BP	GO:0007492	endoderm development	15/232	87/18986	0.172413793103448	14.1096908442331	13.6312286065914	1.55082628672401e-13	1.89466662915196e-11	9.46353845342258e-12	MMP2/MYH9/ITGB2/INHBA/MMP9/MMP8/MMP14/COL5A1/COL6A1/COL11A1/COL4A2/COL5A2/LAMA3/LAMB1/LAMB3	15
BP	GO:0050818	regulation of coagulation	14/232	76/18986	0.184210526315789	15.0750907441016	13.6745981437835	3.92540817792318e-13	4.66251260244431e-11	2.32884596286729e-11	PDGFRA/CPB2/PRKCD/PLAU/PLAUR/EPHB2/F2/FGA/FGB/FGG/PLAT/PDGFA/PF4/PLG	14
BP	GO:0051402	neuron apoptotic process	24/232	307/18986	0.0781758957654723	6.39761878018645	10.6046642304136	5.64046150980831e-13	6.51854416647037e-11	3.25590224847826e-11	KDR/NTRK1/NTRK2/MMP2/NR4A2/ITGA1/SNCA/RHOA/EGR1/ATM/XIAP/TP53/COL6A1/COL6A2/COL6A3/THRB/HTR2A/BRAF/NRP1/GRN/TNF/NPR2/BCL2L1/BCL2	24
BP	GO:0007369	gastrulation	20/232	202/18986	0.099009900990099	8.10259474223284	11.2875845860954	6.76271651087608e-13	7.6098357369753e-11	3.80098387827357e-11	MMP2/NR4A3/APOA1/MYH9/ITGB1/ITGB2/INHBA/MMP9/MMP8/MMP14/TP53/COL5A1/COL6A1/COL11A1/COL4A2/COL5A2/LAMA3/LAMB1/LAMB3/HNF4A	20
BP	GO:2001233	regulation of apoptotic signaling pathway	27/232	403/18986	0.0669975186104218	5.48282279455806	10.116924723374	7.43120808927482e-13	8.14765276659978e-11	4.06961436252054e-11	MMP2/NR4A2/ICAM1/INHBA/MMP9/PRKCD/HSPA1A/PLAUR/TP53/LMNA/MDM2/FGA/FGB/FGG/COL2A1/RAF1/PPIA/TGFBR1/PF4/NRP1/INS/TNF/HGF/AR/BCL2L1/BCL2/PTGS2	27
BP	GO:0006979	response to oxidative stress	27/232	405/18986	0.0666666666666667	5.45574712643678	10.0812838501947	8.35287605344388e-13	8.92922450113151e-11	4.45999618748359e-11	MMP2/NR4A2/SNCA/PDGFRA/EDNRA/PRKCD/CHUK/ATM/MMP3/HSPA1A/CDK1/MMP14/CYP1B1/MAP1LC3A/TP53/MDM2/COL1A1/COL6A1/PPIA/HSPA8/TRPA1/HGF/ALOX5/MAPT/PTGS1/BCL2/PTGS2	27
BP	GO:1903035	negative regulation of response to wounding	15/232	101/18986	0.148514851485149	12.1538921133493	12.5006031792168	1.50724601845228e-12	1.57194731095169e-10	7.85161019625077e-11	PDGFRA/CPB2/PRKCD/PLAU/PLAUR/F2/FGA/FGB/FGG/PLAT/PDGFA/PF4/TNF/PLG/ALOX5	15
BP	GO:0030168	platelet activation	17/232	141/18986	0.120567375886525	9.86677671802397	11.753835141598	1.55410834294334e-12	1.58223030343469e-10	7.90297199957902e-11	PRKCA/PDGFRA/MYH9/PRKCD/PRKCQ/FLNA/GLA/F2/FGA/FGB/FGG/COL3A1/HTR2A/PPIA/PDGFA/PF4/SLC6A4	17
BP	GO:0072593	reactive oxygen species metabolic process	21/232	242/18986	0.0867768595041322	7.10148902821317	10.6246520765472	2.31074531247645e-12	2.27726156482377e-10	1.13745352642101e-10	SNCA/RHOA/PDGFRB/SHC1/ITGB2/MAOB/PRKCD/MMP3/CYP1A1/CYP1A2/CYP1B1/TP53/F2/COL6A1/INS/CLEC7A/LIPA/TNF/ALOX5/MAPT/BCL2	21
BP	GO:0060326	cell chemotaxis	24/232	328/18986	0.0731707317073171	5.98801513877208	10.135250282412	2.34330001993091e-12	2.27726156482377e-10	1.13745352642101e-10	VEGFA/KDR/MMP2/ITGA1/PDE4B/PDGFRB/PDGFRA/ITGB2/PRKCD/PRKCQ/CXCL8/EPHB1/IL17RA/NR4A1/PPIA/CXCR1/PF4/KLRK1/NRP1/FLT1/CXCR2/HGF/ALOX5/PLEC	24
BP	GO:0030199	collagen fibril organization	13/232	72/18986	0.180555555555556	14.7759818007663	13.0256514728567	3.62594666093775e-12	3.44545509381551e-10	1.72094638012695e-10	CYP1B1/COL1A2/COL1A1/COL2A1/COL3A1/COL5A1/COL6A1/COL11A1/COL18A1/COL27A1/COL5A2/COL11A2/TGFBR1	13
BP	GO:0019369	arachidonate metabolic process	12/232	58/18986	0.206896551724138	16.9316290130797	13.5152522329852	4.52791815539728e-12	4.20021752729947e-10	2.09793741393595e-10	PLA2G10/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2S1/ALOX5/PTGS1/ALOX15/PTGS2	12
BP	GO:0043200	response to amino acid	16/232	129/18986	0.124031007751938	10.1502272119754	11.5982581329297	4.61670308192411e-12	4.20021752729947e-10	2.09793741393595e-10	NTRK2/MMP2/PDGFRA/CHUK/MMP3/CDKN1B/COL1A2/COL1A1/COL3A1/COL4A1/COL6A1/COL5A2/COL4A6/TNF/BCL2L1/PTGS2	16
BP	GO:0050900	leukocyte migration	26/232	404/18986	0.0643564356435644	5.26668658245135	9.64134301246819	5.06000209001703e-12	4.46375144775486e-10	2.22956813733805e-10	VEGFA/MMP2/ITGA1/PDE4B/RHOA/MYH9/ITGB1/ITGAL/ICAM1/ITGB2/IL1R1/ITGB7/CXCL8/MMP14/IL17RA/PPIA/CXCR1/B4GALT1/PF4/KLRK1/FLT1/TNF/CXCR2/PLG/ALOX5/PLEC	26
BP	GO:0071230	cellular response to amino acid stimulus	14/232	91/18986	0.153846153846154	12.5901856763926	12.3265056428899	5.19017467581637e-12	4.46375144775486e-10	2.22956813733805e-10	NTRK2/MMP2/PDGFRA/MMP3/COL1A2/COL1A1/COL3A1/COL4A1/COL6A1/COL5A2/COL4A6/TNF/BCL2L1/PTGS2	14
BP	GO:0050727	regulation of inflammatory response	27/232	438/18986	0.0616438356164384	5.04469768540387	9.52526167882652	5.21954098193974e-12	4.46375144775486e-10	2.22956813733805e-10	SNCA/FABP4/APOA1/IL1R1/MMP9/ESR1/PRKCD/RORA/PLA2G2A/ATM/MMP8/MMP3/XIAP/PLA2G10/IL17RA/AHSG/BRD4/IL12B/HTR2A/GRN/INS/TNF/HGF/AHR/ALOX5/ALOX15/PTGS2	27
BP	GO:0007229	integrin-mediated signaling pathway	15/232	111/18986	0.135135135135135	11.0589468779124	11.8215074757049	6.18283755973023e-12	5.18388498145225e-10	2.58926262305318e-10	ITGA1/APOA1/MYH9/ITGB1/ITGAL/ITGB2/ITGB7/ADAMTS1/FLNA/LAMA1/COL3A1/LAMA5/LAMB1/LAMB2/NRP1	15
BP	GO:0001704	formation of primary germ layer	16/232	132/18986	0.121212121212121	9.91954022988506	11.4374713767594	6.6070397737108e-12	5.43301962930526e-10	2.71370115402008e-10	MMP2/MYH9/ITGB1/ITGB2/INHBA/MMP9/MMP8/MMP14/COL5A1/COL6A1/COL11A1/COL4A2/COL5A2/LAMA3/LAMB1/LAMB3	16
BP	GO:0042327	positive regulation of phosphorylation	28/232	479/18986	0.058455114822547	4.78374487077964	9.32876014260077	7.27388093982004e-12	5.86851224503217e-10	2.93122232907544e-10	VEGFA/KDR/NTRK1/NTRK2/SNCA/PDE5A/RHOA/PDGFRB/MMP9/PRKCD/PLAUR/TP53/TPX2/LTF/F2/NTRK3/HTR2A/RAF1/BRAF/PPIA/PDGFA/NRP1/FLT1/INS/TNF/AR/MAPT/PTGS2	28
BP	GO:0043491	phosphatidylinositol 3-kinase/protein kinase B signal transduction	23/232	317/18986	0.0725552050473186	5.9376427716741	9.86032221500886	8.18905334242355e-12	6.48451705411169e-10	3.23890628299754e-10	VEGFA/KDR/NTRK1/NTRK2/PDE3B/PDGFRB/PDGFRA/DDR1/ITGB1/MMP3/IGF2/F2/NTRK3/COL6A1/COL6A2/COL6A3/TGFBR1/PDGFA/FLT1/INS/FCGR3A/TNF/HGF	23
BP	GO:0050673	epithelial cell proliferation	28/232	482/18986	0.0580912863070539	4.75397052511089	9.285042692337	8.43479143117292e-12	6.55766693812644e-10	3.27544340934926e-10	VEGFA/KDR/PRKCA/NR4A3/APOA1/CPB2/ESR1/NRP2/CDKN1B/MMP14/IGF2/NR4A1/IL12B/COL4A3/LAMA5/LAMB1/RAF1/TGFBR1/B4GALT1/NRP1/FLT1/GRN/LIPA/TNF/HGF/AR/ALOX5/BCL2L1	28
BP	GO:0070527	platelet aggregation	13/232	77/18986	0.168831168831169	13.8165024630542	12.5338053069576	8.90350604024432e-12	6.7984628264437e-10	3.39571687136386e-10	PRKCA/PDGFRA/MYH9/PRKCD/PRKCQ/FLNA/GLA/FGA/FGB/FGG/HTR2A/PPIA/SLC6A4	13
BP	GO:0071375	cellular response to peptide hormone stimulus	23/232	321/18986	0.0716510903426791	5.86365345364701	9.7747009494654	1.05782216129567e-11	7.93552203807065e-10	3.9636586616231e-10	NR4A2/PDE3B/CCNA2/PRKCA/NR4A3/SHC1/INHBA/EDNRA/PRKCD/PRKCQ/CYP1B1/AHSG/MDM2/IGF2/NR4A1/COL6A1/RAF1/INS/PPP3CA/HNF4A/PRKCZ/CA2/SRD5A1	23
BP	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	7/232	11/18986	0.636363636363636	52.0775862068966	18.8468230521161	1.17647126838334e-11	8.67343300621923e-10	4.33223267431904e-10	DDR1/COL1A1/COL4A1/COL4A2/COL4A3/COL4A5/COL4A6	7
BP	GO:0070482	response to oxygen levels	24/232	358/18986	0.0670391061452514	5.48622616066269	9.53107527583293	1.49569780532348e-11	1.08400064670563e-09	5.41439937020758e-10	VEGFA/MMP2/NR4A2/CCNA2/EGR1/INHBA/EDNRA/RORA/PLAU/ATM/CDKN1B/MMP14/CYP1A1/MAP1LC3A/TP53/LMNA/MDM2/COL1A1/COL6A1/PLAT/TNF/BCL2/PTGS2/SLC6A4	24
BP	GO:0071216	cellular response to biotic stimulus	21/232	269/18986	0.0780669144981413	6.3887001666453	9.90020931611798	1.74770202119172e-11	1.2455289737693e-09	6.22120596666314e-10	PDE4B/PLAA/PRKCA/RHOA/MMP9/MMP8/CXCL8/MMP3/HSPA5/TP53/EPHB2/ABCA1/LTF/IL12B/PF4/KLRK1/CLEC7A/TNF/HAVCR2/AHR/PTGS2	21
BP	GO:0048511	rhythmic process	22/232	299/18986	0.0735785953177258	6.02139314957906	9.73402291909862	1.81174292161234e-11	1.26310001288166e-09	6.3089703267611e-10	NTRK1/NTRK2/MMP2/DDB1/PDGFRA/KCNA2/EGR1/INHBA/ESR1/RORA/CDK1/ADAMTS1/CYP1B1/TP53/COL6A1/HSPA8/TNF/NPR2/HNF4A/AHR/SLC6A4/DYRK1A	22
BP	GO:2001236	regulation of extrinsic apoptotic signaling pathway	17/232	164/18986	0.103658536585366	8.48302144659378	10.7045488095348	1.8314359400997e-11	1.26310001288166e-09	6.3089703267611e-10	ICAM1/INHBA/HSPA1A/LMNA/FGA/FGB/FGG/COL2A1/RAF1/TGFBR1/PF4/NRP1/TNF/HGF/AR/BCL2L1/BCL2	17
BP	GO:0036293	response to decreased oxygen levels	23/232	331/18986	0.0694864048338369	5.68650380247943	9.56682172935991	1.97313564637419e-11	1.33922667045969e-09	6.68921006932871e-10	VEGFA/MMP2/NR4A2/CCNA2/EGR1/INHBA/EDNRA/RORA/PLAU/ATM/CDKN1B/MMP14/CYP1A1/MAP1LC3A/TP53/LMNA/MDM2/COL6A1/PLAT/TNF/BCL2/PTGS2/SLC6A4	23
BP	GO:0042730	fibrinolysis	9/232	27/18986	0.333333333333333	27.2787356321839	15.1978086444081	2.01322216463979e-11	1.34508405874996e-09	6.7184667303522e-10	CPB2/PLAU/PLAUR/F2/FGA/FGB/FGG/PLAT/PLG	9
BP	GO:0034109	homotypic cell-cell adhesion	14/232	101/18986	0.138613861386139	11.343632639126	11.592513692916	2.23771311616466e-11	1.47207096688001e-09	7.35274479789164e-10	PRKCA/PDGFRA/MYH9/PRKCD/PRKCQ/PLAUR/FLNA/GLA/FGA/FGB/FGG/HTR2A/PPIA/SLC6A4	14
BP	GO:0006690	icosanoid metabolic process	15/232	124/18986	0.120967741935484	9.89954115684094	11.058263277628	3.15327923319152e-11	2.04294272744347e-09	1.02041524149052e-09	PLAA/PLA2G5/PLA2G10/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2S1/LTA4H/ALOX5/PTGS1/ALOX15/PTGS2	15
BP	GO:0010810	regulation of cell-substrate adhesion	19/232	223/18986	0.0852017937219731	6.97259161898871	9.97852730597698	3.68745050057388e-11	2.32691089936639e-09	1.16225252691015e-09	VEGFA/KDR/RHOA/APOA1/DDR1/PLAU/MMP14/CDKN2A/FLNA/FGA/FGB/FGG/COL1A1/BRAF/NRP1/PLG/PRKCZ/BCL2/ALOX15	19
BP	GO:0034599	cellular response to oxidative stress	20/232	251/18986	0.0796812749003984	6.52081329853002	9.79299222941331	3.73615360256549e-11	2.32691089936639e-09	1.16225252691015e-09	MMP2/NR4A2/SNCA/PDGFRA/EDNRA/PRKCD/ATM/MMP3/HSPA1A/CDK1/CYP1B1/MAP1LC3A/TP53/MDM2/PPIA/HSPA8/TRPA1/HGF/ALOX5/MAPT	20
BP	GO:0009314	response to radiation	26/232	442/18986	0.0588235294117647	4.81389452332657	9.02361257491056	3.75483751300937e-11	2.32691089936639e-09	1.16225252691015e-09	MMP2/MMP1/HMGCR/DDB1/PDE6C/PDE8B/ITGB1/EGR1/MMP9/PRKCD/ATM/ATR/MMP3/CYP2R1/TP53/MDM2/IL12B/COL3A1/COL6A1/COL6A2/COL6A3/BRAF/POLD3/TNF/BCL2L1/BCL2	26
BP	GO:0002237	response to molecule of bacterial origin	24/232	375/18986	0.064	5.23751724137931	9.21816749213549	3.93795149210913e-11	2.40552579717981e-09	1.20151933496082e-09	SNCA/PDE4B/PLAA/PRKCA/RHOA/MMP9/MAOB/MMP8/CXCL8/MMP3/XIAP/CYP1A1/EPHB2/NR4A1/ABCA1/LTF/IL12B/COL6A1/PF4/KLRK1/TNF/HAVCR2/AHR/PTGS2	24
BP	GO:0071466	cellular response to xenobiotic stimulus	18/232	198/18986	0.0909090909090909	7.43965517241379	10.1311155640143	4.19647312977734e-11	2.52734071872224e-09	1.26236382213762e-09	PDE4A/PDE4B/RORA/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2R1/CYP2S1/TP53/ABCA1/BPHL/BRAF/HNF4A/AHR	18
BP	GO:0001654	eye development	25/232	411/18986	0.0608272506082725	4.97787146572699	9.06795973468403	4.48941726188928e-11	2.66621502942202e-09	1.3317291848499e-09	VEGFA/KDR/NTRK2/PDE6A/PDE6C/PDGFRB/PDGFRA/INHBA/CDKN1B/SMARCA4/CYP1A1/CYP1B1/EPHB2/EPHB1/LAMA1/COL4A1/COL5A1/COL5A2/LAMB2/THRB/TGFBR1/NRP1/FLT1/BCL2/SLC6A3	25
BP	GO:0150063	visual system development	25/232	415/18986	0.0602409638554217	4.92989198171998	9.0030436151824	5.52033428951297e-11	3.23355471533664e-09	1.61510573517258e-09	VEGFA/KDR/NTRK2/PDE6A/PDE6C/PDGFRB/PDGFRA/INHBA/CDKN1B/SMARCA4/CYP1A1/CYP1B1/EPHB2/EPHB1/LAMA1/COL4A1/COL5A1/COL5A2/LAMB2/THRB/TGFBR1/NRP1/FLT1/BCL2/SLC6A3	25
BP	GO:2000377	regulation of reactive oxygen species metabolic process	16/232	153/18986	0.104575163398693	8.55803470813613	10.4399202593298	6.39743841151914e-11	3.69668197941295e-09	1.84642994836022e-09	SNCA/RHOA/PDGFRB/SHC1/ITGB2/PRKCD/MMP3/CYP1B1/TP53/F2/INS/CLEC7A/TNF/ALOX5/MAPT/BCL2	16
BP	GO:0001934	positive regulation of protein phosphorylation	26/232	455/18986	0.0571428571428571	4.67635467980296	8.82827822031238	7.09841229163598e-11	4.04704146120473e-09	2.02142856697956e-09	VEGFA/KDR/NTRK1/NTRK2/SNCA/PDE5A/RHOA/PDGFRB/MMP9/PRKCD/PLAUR/TP53/TPX2/LTF/F2/NTRK3/HTR2A/RAF1/BRAF/PPIA/PDGFA/NRP1/FLT1/INS/TNF/PTGS2	26
BP	GO:0062197	cellular response to chemical stress	22/232	321/18986	0.0685358255451713	5.60871199914062	9.26233375448092	7.21132033812103e-11	4.05731654813231e-09	2.02656079862155e-09	MMP2/NR4A2/SNCA/PDGFRA/EDNRA/PRKCD/ATM/MMP3/HSPA1A/CDK1/CYP1B1/MAP1LC3A/TP53/MDM2/PPIA/HSPA8/TRPA1/HGF/ALOX5/MAPT/PTGS2/PLEC	22
BP	GO:0032496	response to lipopolysaccharide	23/232	354/18986	0.0649717514124294	5.3170416910189	9.11927837942992	7.61539808848882e-11	4.22901847095821e-09	2.11232299679341e-09	SNCA/PDE4B/PLAA/PRKCA/RHOA/MMP9/MAOB/MMP8/CXCL8/MMP3/XIAP/CYP1A1/EPHB2/NR4A1/ABCA1/LTF/IL12B/COL6A1/PF4/KLRK1/TNF/HAVCR2/PTGS2	23
BP	GO:0048880	sensory system development	25/232	422/18986	0.0592417061611374	4.84811652230757	8.8914173754281	7.87958625190249e-11	4.31962959142757e-09	2.15758171458976e-09	VEGFA/KDR/NTRK2/PDE6A/PDE6C/PDGFRB/PDGFRA/INHBA/CDKN1B/SMARCA4/CYP1A1/CYP1B1/EPHB2/EPHB1/LAMA1/COL4A1/COL5A1/COL5A2/LAMB2/THRB/TGFBR1/NRP1/FLT1/BCL2/SLC6A3	25
BP	GO:0032963	collagen metabolic process	14/232	111/18986	0.126126126126126	10.3216837527182	10.9550587657329	8.23341100973331e-11	4.45646398450882e-09	2.22592817305115e-09	MMP2/MMP1/ITGB1/INHBA/MMP9/MMP8/MMP13/MMP3/MMP14/F2/COL1A2/COL1A1/COL5A1/COL6A1	14
BP	GO:1903522	regulation of blood circulation	20/232	267/18986	0.0749063670411985	6.13005295105256	9.38941411258631	1.13540790473523e-10	6.0466432597616e-09	3.02019574960767e-09	MMP2/PDE5A/PDE4D/PDE4B/RHOA/ITGB1/EDNRA/THRA/FLNA/MYH7/MDM2/FGA/FGB/FGG/THRB/HTR1A/HTR2A/TNF/PTGS2/ADORA3	20
BP	GO:0018105	peptidyl-serine phosphorylation	16/232	159/18986	0.10062893081761	8.23509000216873	10.1895329064589	1.14541184293894e-10	6.0466432597616e-09	3.02019574960767e-09	SNCA/PDE4D/CDK2/PRKCD/IKBKB/ATM/ATR/CDK1/NTRK3/RAF1/BRAF/TGFBR1/TNF/PRKCZ/PTGS2/DYRK1A	16
BP	GO:0051090	regulation of DNA-binding transcription factor activity	23/232	363/18986	0.0633608815426997	5.18521421107628	8.95464801635219	1.25485665037267e-10	6.54361833779698e-09	3.26842637176655e-09	NTRK1/ESR1/PRKCH/PRKCQ/IKBKB/CHUK/HSPA1A/ESR2/SMARCA4/PLA2G10/CYP1B1/CDKN2A/FLNA/IL18R1/LTF/PPIA/INS/CLEC7A/TNF/HAVCR2/PRKCZ/AR/ADORA3	23
BP	GO:0007160	cell-matrix adhesion	19/232	241/18986	0.0788381742738589	6.45181714122192	9.47347726132499	1.41038398885986e-10	7.26602642935513e-09	3.62925696055378e-09	VEGFA/KDR/ITGA1/RHOA/DDR1/ITGB1/ITGAL/ITGB2/PLAU/ITGB7/MMP14/CDKN2A/FGA/FGB/FGG/COL3A1/NRP1/PRKCZ/BCL2	19
BP	GO:0120254	olefinic compound metabolic process	16/232	163/18986	0.098159509202454	8.033001903956	10.0298041660323	1.665210241705e-10	8.47671308753642e-09	4.2339744115532e-09	EGR1/INHBA/PLA2G10/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2S1/ALOX5/PTGS1/ALOX15/PTGS2/SRD5A1	16
BP	GO:0038065	collagen-activated signaling pathway	7/232	15/18986	0.466666666666667	38.1902298850575	16.026242787416	2.20046061110232e-10	1.10696112624394e-08	5.52908307111654e-09	DDR1/COL1A1/COL4A1/COL4A2/COL4A3/COL4A5/COL4A6	7
BP	GO:0051897	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	17/232	192/18986	0.0885416666666667	7.24591415229885	9.6747410824756	2.24623216216822e-10	1.11684752621294e-08	5.57846396210443e-09	VEGFA/KDR/NTRK1/NTRK2/PDGFRB/PDGFRA/DDR1/ITGB1/IGF2/F2/NTRK3/TGFBR1/PDGFA/FLT1/INS/TNF/HGF	17
BP	GO:0048608	reproductive structure development	21/232	309/18986	0.0679611650485437	5.56168396384332	8.99193608948804	2.32362449028693e-10	1.14204808281229e-08	5.70433646798812e-09	VEGFA/KDR/NTRK1/MMP2/PDGFRA/PSAP/INHBA/ESR1/ATM/CDKN1B/ADAMTS1/MMP14/CYP1B1/FLNA/COL6A1/TGFBR1/NPR2/AR/BCL2L1/BCL2/SRD5A1	21
BP	GO:0010038	response to metal ion	22/232	345/18986	0.063768115942029	5.21854072963518	8.79507461400931	2.86894683463198e-10	1.39404734828254e-08	6.96303005678024e-09	SNCA/FABP4/MAOB/CDK1/CDKN1B/CYP1A1/CYP1A2/CYP2R1/MAP1LC3A/MDM2/LTA4H/FGA/FGB/FGG/BRAF/HSPA8/PPP3CA/MAPT/BCL2/ALOX15/PTGS2/SLC6A3	22
BP	GO:0061458	reproductive system development	21/232	313/18986	0.0670926517571885	5.49060813043957	8.90989561118377	2.94262009791031e-10	1.41325427087561e-08	7.05896537739799e-09	VEGFA/KDR/NTRK1/MMP2/PDGFRA/PSAP/INHBA/ESR1/ATM/CDKN1B/ADAMTS1/MMP14/CYP1B1/FLNA/COL6A1/TGFBR1/NPR2/AR/BCL2L1/BCL2/SRD5A1	21
BP	GO:0051092	positive regulation of NF-kappaB transcription factor activity	14/232	122/18986	0.114754098360656	9.39104013566987	10.3414433489466	2.97457634188037e-10	1.41325427087561e-08	7.05896537739799e-09	NTRK1/PRKCH/PRKCQ/IKBKB/CHUK/HSPA1A/IL18R1/LTF/PPIA/INS/CLEC7A/TNF/PRKCZ/AR	14
BP	GO:0018209	peptidyl-serine modification	16/232	171/18986	0.0935672514619883	7.65718894938496	9.72610972654948	3.41096323965033e-10	1.60277789151042e-08	8.00560371688898e-09	SNCA/PDE4D/CDK2/PRKCD/IKBKB/ATM/ATR/CDK1/NTRK3/RAF1/BRAF/TGFBR1/TNF/PRKCZ/PTGS2/DYRK1A	16
BP	GO:0022617	extracellular matrix disassembly	11/232	65/18986	0.169230769230769	13.8492042440318	11.5415252302724	3.58620968910831e-10	1.66680789463339e-08	8.32542272219768e-09	MMP2/MMP1/DDR1/MMP9/MMP8/MMP13/MMP3/ADAMTS4/MMP14/ADAMTS5/PLG	11
BP	GO:0001666	response to hypoxia	21/232	317/18986	0.0662460567823344	5.42132600891983	8.8292533667371	3.71286747017329e-10	1.70712057015709e-08	8.52677769890391e-09	VEGFA/MMP2/NR4A2/CCNA2/EGR1/INHBA/EDNRA/RORA/PLAU/ATM/CDKN1B/MMP14/CYP1A1/TP53/LMNA/MDM2/PLAT/TNF/BCL2/PTGS2/SLC6A4	21
BP	GO:0035296	regulation of tube diameter	15/232	154/18986	0.0974025974025974	7.97105911330049	9.66080331809131	7.02805673672942e-10	3.16336532697421e-08	1.58004732618548e-08	VEGFA/MMP2/ITGA1/RHOA/ITGB1/EDNRA/FGA/FGB/FGG/HTR1A/HTR2A/INS/TNF/PTGS2/SLC6A4	15
BP	GO:0097746	blood vessel diameter maintenance	15/232	154/18986	0.0974025974025974	7.97105911330049	9.66080331809131	7.02805673672942e-10	3.16336532697421e-08	1.58004732618548e-08	VEGFA/MMP2/ITGA1/RHOA/ITGB1/EDNRA/FGA/FGB/FGG/HTR1A/HTR2A/INS/TNF/PTGS2/SLC6A4	15
BP	GO:0043010	camera-type eye development	22/232	362/18986	0.0607734806629834	4.9734711373595	8.48965816628082	7.11554288423302e-10	3.16938139301879e-08	1.58305224913474e-08	VEGFA/KDR/NTRK2/PDE6A/PDE6C/PDGFRB/PDGFRA/INHBA/CDKN1B/SMARCA4/CYP1A1/CYP1B1/EPHB2/EPHB1/LAMA1/COL4A1/LAMB2/THRB/TGFBR1/NRP1/FLT1/SLC6A3	22
BP	GO:0046777	protein autophosphorylation	16/232	180/18986	0.0888888888888889	7.27432950191571	9.40714192671368	7.30013904579691e-10	3.21808191338429e-08	1.60737733303548e-08	VEGFA/KDR/NTRK1/NTRK2/PDGFRB/PDGFRA/DDR1/ATM/ATR/EPHB3/EPHB1/EPHB4/PDGFA/FLT1/INS/DYRK1A	16
BP	GO:0008406	gonad development	18/232	236/18986	0.076271186440678	6.24174459380479	9.01225681042511	7.49134421970505e-10	3.268672233006e-08	1.63264633961134e-08	VEGFA/KDR/NTRK1/MMP2/PDGFRA/INHBA/ESR1/ATM/ADAMTS1/MMP14/CYP1B1/FLNA/TGFBR1/NPR2/AR/BCL2L1/BCL2/SRD5A1	18
BP	GO:0035150	regulation of tube size	15/232	155/18986	0.0967741935483871	7.91963292547275	9.62087453850138	7.69758751487416e-10	3.32473577915171e-08	1.66064913000316e-08	VEGFA/MMP2/ITGA1/RHOA/ITGB1/EDNRA/FGA/FGB/FGG/HTR1A/HTR2A/INS/TNF/PTGS2/SLC6A4	15
BP	GO:0051091	positive regulation of DNA-binding transcription factor activity	17/232	208/18986	0.0817307692307692	6.68853614058355	9.17507998731797	7.8074328988188e-10	3.33845830753492e-08	1.6675033001793e-08	NTRK1/ESR1/PRKCH/PRKCQ/IKBKB/CHUK/HSPA1A/ESR2/SMARCA4/IL18R1/LTF/PPIA/INS/CLEC7A/TNF/PRKCZ/AR	17
BP	GO:0001676	long-chain fatty acid metabolic process	13/232	109/18986	0.119266055045872	9.76028155646947	10.2015735039711	8.02736613754436e-10	3.39851659446927e-08	1.69750139583924e-08	PLA2G10/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2S1/ALOX5/PTGS1/ALOX15/PTGS2	13
BP	GO:0009411	response to UV	15/232	157/18986	0.0955414012738854	7.81874588183615	9.54207973958644	9.21515997997784e-10	3.86313961513581e-08	1.92957271407379e-08	MMP2/MMP1/DDB1/MMP9/PRKCD/ATR/MMP3/TP53/MDM2/IL12B/COL6A1/COL6A2/COL6A3/POLD3/BCL2	15
BP	GO:0008202	steroid metabolic process	21/232	334/18986	0.062874251497006	5.14539025397481	8.50116194353069	9.59427448322212e-10	3.98302113497649e-08	1.98945149989348e-08	HMGCR/PDE8B/APOA1/PDGFRA/EGR1/INHBA/ESR1/RORA/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2R1/ABCA1/PON1/LIPA/TNF/SRD5A1	21
BP	GO:0045137	development of primary sexual characteristics	18/232	241/18986	0.0746887966804979	6.11224781799971	8.88341670374215	1.049971478852e-09	4.31699811881842e-08	2.15626733865456e-08	VEGFA/KDR/NTRK1/MMP2/PDGFRA/INHBA/ESR1/ATM/ADAMTS1/MMP14/CYP1B1/FLNA/TGFBR1/NPR2/AR/BCL2L1/BCL2/SRD5A1	18
BP	GO:0071219	cellular response to molecule of bacterial origin	18/232	242/18986	0.0743801652892562	6.08699059561129	8.85808446841794	1.12217690036614e-09	4.56993183425298e-08	2.28260343944151e-08	PDE4B/PLAA/PRKCA/RHOA/MMP9/MMP8/CXCL8/MMP3/EPHB2/ABCA1/LTF/IL12B/PF4/KLRK1/TNF/HAVCR2/AHR/PTGS2	18
BP	GO:0002697	regulation of immune effector process	23/232	410/18986	0.0560975609756098	4.59081160639193	8.17543339624936	1.3547863101728e-09	5.46515685122536e-08	2.72975315128164e-08	NR4A3/APOA1/ICAM1/ITGB2/IL1R1/PLA2G5/EPHB2/IL18R1/BRD4/IL12B/HTR2A/HSPA8/KLRK1/MICA/HLA-A/TNFSF13/GRN/INS/CLEC7A/TNF/HAVCR2/PRKCZ/AHR	23
BP	GO:0033559	unsaturated fatty acid metabolic process	13/232	114/18986	0.114035087719298	9.33219903206292	9.92442683826807	1.40980800318153e-09	5.63396170243386e-08	2.81406831131857e-08	PLAA/PLA2G10/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2S1/ALOX5/PTGS1/ALOX15/PTGS2	13
BP	GO:0019933	cAMP-mediated signaling	10/232	57/18986	0.175438596491228	14.3572292800968	11.23291080491	1.59751264366311e-09	6.32496672620689e-08	3.1592136003825e-08	PDE5A/PDE4A/PDE3A/PDE4D/PDE4B/PDE6A/PDE3B/PDE6C/PDE8B/AHR	10
BP	GO:0016049	cell growth	25/232	490/18986	0.0510204081632653	4.1753166783955	7.92042550364083	1.76638659997967e-09	6.90594577867983e-08	3.44940278296031e-08	VEGFA/PLAA/DDR1/ITGB1/INHBA/EDNRA/PRKCQ/NRP2/HSPA1A/ESR2/CDKN1B/SMARCA4/MMP14/TP53/CDKN2A/F2/LAMB2/TGFBR1/NRP1/INS/NPR2/HNF4A/PRKCZ/MAPT/BCL2	25
BP	GO:0051896	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	19/232	280/18986	0.0678571428571429	5.55317118226601	8.53699184347887	1.77655293651726e-09	6.90594577867983e-08	3.44940278296031e-08	VEGFA/KDR/NTRK1/NTRK2/PDE3B/PDGFRB/PDGFRA/DDR1/ITGB1/MMP3/IGF2/F2/NTRK3/TGFBR1/PDGFA/FLT1/INS/TNF/HGF	19
BP	GO:0001541	ovarian follicle development	10/232	58/18986	0.172413793103448	14.1096908442331	11.1213221391738	1.9098412513398e-09	7.357190261918e-08	3.67479174866615e-08	VEGFA/KDR/MMP2/INHBA/ESR1/ATM/MMP14/NPR2/BCL2L1/BCL2	10
BP	GO:0023061	signal release	25/232	493/18986	0.050709939148073	4.14990907183325	7.88170415640558	2.00021830165267e-09	7.63654773023822e-08	3.81432606583953e-08	SNCA/PDE8B/PRKCA/KCNA2/INHBA/MAOB/PLA2G10/NR4A1/ABCA1/F2/FGA/FGB/FGG/HTR1A/HTR2A/RAF1/BRAF/INS/TNF/PPP3CA/HNF4A/ALOX5/PTGS2/SLC6A4/ADORA3	25
BP	GO:0043523	regulation of neuron apoptotic process	18/232	254/18986	0.0708661417322835	5.79941623676351	8.56476670058324	2.43109647978361e-09	9.19944119252628e-08	4.59496484162174e-08	KDR/NTRK1/NTRK2/MMP2/NR4A2/ITGA1/SNCA/RHOA/EGR1/ATM/TP53/HTR2A/BRAF/NRP1/GRN/TNF/BCL2L1/BCL2	18
BP	GO:0000082	G1/S transition of mitotic cell cycle	18/232	256/18986	0.0703125	5.75410829741379	8.51770317967523	2.75352238045181e-09	1.03281242972034e-07	5.15872290852883e-08	CDC7/CDK2/CCNA2/SKP2/ITGB1/INHBA/ATM/CDK1/CDKN1B/ADAMTS1/SMARCA4/CYP1A1/TP53/CDKN2A/MDM2/HSPA8/PPP3CA/BCL2	18
BP	GO:0071222	cellular response to lipopolysaccharide	17/232	228/18986	0.0745614035087719	6.10182244404114	8.61989221025643	3.18317922147501e-09	1.18358907400236e-07	5.91182667311011e-08	PDE4B/PLAA/PRKCA/RHOA/MMP9/MMP8/CXCL8/MMP3/EPHB2/ABCA1/LTF/IL12B/PF4/KLRK1/TNF/HAVCR2/PTGS2	17
BP	GO:0046660	female sex differentiation	13/232	122/18986	0.10655737704918	8.72025155455059	9.51473748190195	3.27838357420964e-09	1.20848001407935e-07	6.03615269697945e-08	VEGFA/KDR/MMP2/PDGFRA/INHBA/ESR1/ATM/ADAMTS1/MMP14/NPR2/BCL2L1/BCL2/SRD5A1	13
BP	GO:0007159	leukocyte cell-cell adhesion	23/232	430/18986	0.0534883720930233	4.37728548516439	7.87883774352433	3.36723512434414e-09	1.22423640485226e-07	6.11485319640894e-08	PDE5A/NR4A3/RHOA/ITGB1/ITGAL/ICAM1/ITGB2/PRKCQ/ITGB7/SMARCA4/PLA2G5/CDKN2A/BRD4/IGF2/IL12B/KLRK1/OLR1/HLA-A/TNF/PPP3CA/HAVCR2/PRKCZ/ALOX5	23
BP	GO:0000302	response to reactive oxygen species	16/232	200/18986	0.08	6.54689655172414	8.77102285456583	3.40701899385919e-09	1.22423640485226e-07	6.11485319640894e-08	MMP2/PDGFRA/PRKCD/ATM/MMP3/CDK1/CYP1B1/MAP1LC3A/MDM2/COL1A1/COL6A1/HSPA8/TRPA1/HGF/MAPT/BCL2	16
BP	GO:0031334	positive regulation of protein-containing complex assembly	16/232	200/18986	0.08	6.54689655172414	8.77102285456583	3.40701899385919e-09	1.22423640485226e-07	6.11485319640894e-08	VEGFA/MMP1/SNCA/CRBN/RHOA/ATM/ATR/MMP3/HSPA1A/CDKN1B/TP53/ABCA1/CLEC7A/TNF/MAPT/ALOX15	16
BP	GO:0007548	sex differentiation	19/232	292/18986	0.0650684931506849	5.32495866792631	8.28370463672077	3.5568335050281e-09	1.26741833895835e-07	6.33053963307195e-08	VEGFA/KDR/NTRK1/MMP2/PDGFRA/INHBA/ESR1/ATM/ADAMTS1/MMP14/CYP1B1/FLNA/TGFBR1/NPR2/HNF4A/AR/BCL2L1/BCL2/SRD5A1	19
BP	GO:0009416	response to light stimulus	20/232	326/18986	0.0613496932515337	5.0206261899725	8.1442109649163	3.73168542723525e-09	1.31873445345933e-07	6.5868549211486e-08	MMP2/MMP1/HMGCR/DDB1/PDE6C/PDE8B/ITGB1/MMP9/PRKCD/ATR/MMP3/TP53/MDM2/IL12B/COL6A1/COL6A2/COL6A3/BRAF/POLD3/BCL2	20
BP	GO:0034446	substrate adhesion-dependent cell spreading	12/232	101/18986	0.118811881188119	9.72311369067941	9.77633472031433	3.81272239380092e-09	1.33565115121813e-07	6.67135095716998e-08	RHOA/APOA1/ITGB7/EPHB3/FLNA/FGA/FGB/FGG/LAMA5/LAMB1/BRAF/NRP1	12
BP	GO:0043254	regulation of protein-containing complex assembly	23/232	433/18986	0.0531177829099307	4.34695787210321	7.83591036034389	3.84202739943476e-09	1.33565115121813e-07	6.67135095716998e-08	VEGFA/MMP1/SNCA/CRBN/RHOA/PRKCD/THRA/ATM/ATR/MMP3/HSPA1A/CDKN1B/HSPA5/TP53/ABCA1/RAF1/HSPA8/CLEC7A/TNF/PRKCZ/MAPT/ALOX15/DYRK1A	23
BP	GO:0001935	endothelial cell proliferation	16/232	202/18986	0.0792079207920792	6.48207579378627	8.71222369788419	3.93428512951529e-09	1.35669380756511e-07	6.77645545652505e-08	VEGFA/KDR/PRKCA/APOA1/NRP2/MMP14/IGF2/NR4A1/IL12B/COL4A3/TGFBR1/NRP1/FLT1/LIPA/TNF/ALOX5	16
BP	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	22/232	400/18986	0.055	4.50099137931034	7.87100898184089	4.52787508224256e-09	1.5391757596558e-07	7.68792185599336e-08	ICAM1/IL1R1/MASP2/PRKCD/PRKCQ/RORA/FCGR2A/EPHB2/IL17RA/IL18R1/BRD4/IL12B/HSPA8/MICA/HLA-A/TNFSF13/CLEC7A/FCGR3A/TNF/HAVCR2/PRKCZ/AHR	22
BP	GO:0018108	peptidyl-tyrosine phosphorylation	16/232	204/18986	0.0784313725490196	6.4185260311021	8.65421473522067	4.53545710282112e-09	1.5391757596558e-07	7.68792185599336e-08	VEGFA/KDR/NTRK1/PDGFRB/PDGFRA/DDR1/ITGB2/PRKCD/TP53/EPHB2/HTR2A/PDGFA/NRP1/FLT1/PRKCZ/DYRK1A	16
BP	GO:0008585	female gonad development	12/232	103/18986	0.116504854368932	9.53431536658855	9.65948873478811	4.78695169668467e-09	1.61173271299399e-07	8.05033153134952e-08	VEGFA/KDR/MMP2/PDGFRA/INHBA/ESR1/ATM/ADAMTS1/MMP14/NPR2/BCL2L1/BCL2	12
BP	GO:0018212	peptidyl-tyrosine modification	16/232	206/18986	0.0776699029126214	6.35621024439237	8.59697708945778	5.2198158948457e-09	1.74374474737189e-07	8.70970925217264e-08	VEGFA/KDR/NTRK1/PDGFRB/PDGFRA/DDR1/ITGB2/PRKCD/TP53/EPHB2/HTR2A/PDGFA/NRP1/FLT1/PRKCZ/DYRK1A	16
BP	GO:0097191	extrinsic apoptotic signaling pathway	17/232	236/18986	0.0720338983050847	5.89498100526008	8.41605788151066	5.3605282098114e-09	1.75610033209797e-07	8.77142330221747e-08	ICAM1/INHBA/HSPA1A/LMNA/FGA/FGB/FGG/COL2A1/RAF1/TGFBR1/PF4/NRP1/TNF/HGF/AR/BCL2L1/BCL2	17
BP	GO:0006805	xenobiotic metabolic process	13/232	127/18986	0.102362204724409	8.37693456421396	9.27728287022547	5.38000803332165e-09	1.75610033209797e-07	8.77142330221747e-08	RORA/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2R1/CYP2S1/BPHL/HNF4A/AHR	13
BP	GO:0022612	gland morphogenesis	13/232	127/18986	0.102362204724409	8.37693456421396	9.27728287022547	5.38000803332165e-09	1.75610033209797e-07	8.77142330221747e-08	MMP2/DDR1/CPB2/ESR1/LAMA1/LAMA5/PDGFA/NRP1/LIPA/TNF/HGF/AR/BCL2	13
BP	GO:0022409	positive regulation of cell-cell adhesion	20/232	336/18986	0.0595238095238095	4.87120279146141	7.96303235315831	6.24293781011221e-09	2.02233349060908e-07	1.01012127725021e-07	NR4A3/RHOA/ITGB2/PRKCQ/SMARCA4/PLAUR/BRD4/IGF2/FGA/FGB/FGG/IL12B/HTR2A/KLRK1/HLA-A/TNF/PPP3CA/HAVCR2/PRKCZ/ALOX5	20
BP	GO:0046545	development of primary female sexual characteristics	12/232	107/18986	0.11214953271028	9.1778923622301	9.43509164708582	7.43346401198321e-09	2.38988662520603e-07	1.19370783381986e-07	VEGFA/KDR/MMP2/PDGFRA/INHBA/ESR1/ATM/ADAMTS1/MMP14/NPR2/BCL2L1/BCL2	12
BP	GO:0150076	neuroinflammatory response	11/232	86/18986	0.127906976744186	10.4674218123496	9.78706309271916	7.82733755404133e-09	2.49773846127468e-07	1.24757799663392e-07	SNCA/ITGB1/ITGB2/MMP9/ATM/MMP8/MMP3/GRN/TNF/MAPT/PTGS2	11
BP	GO:0022411	cellular component disassembly	23/232	450/18986	0.0511111111111111	4.18273946360153	7.59979141853843	7.94019101427175e-09	2.51498198348341e-07	1.25619084350545e-07	MMP2/MMP1/PRKCA/DDR1/ITGB1/MMP9/ATR/MMP8/MMP13/MMP3/ADAMTS4/CDK1/SMARCA4/MMP14/MAP1LC3A/CDKN2A/TPX2/COL6A1/ADAMTS5/HSPA8/TGFBR1/TNF/PLG	23
BP	GO:0042310	vasoconstriction	11/232	88/18986	0.125	10.229525862069	9.65195174932256	1.00233027032563e-08	3.15144429111207e-07	1.57409297096804e-07	MMP2/RHOA/ITGB1/EDNRA/FGA/FGB/FGG/HTR1A/HTR2A/PTGS2/SLC6A4	11
BP	GO:0038084	vascular endothelial growth factor signaling pathway	9/232	51/18986	0.176470588235294	14.4416835699797	10.6907565068296	1.01298542505801e-08	3.15219779038408e-07	1.57446933107412e-07	VEGFA/KDR/PDGFRB/PDGFRA/ITGB1/NRP2/IL12B/NRP1/FLT1	9
BP	GO:0001503	ossification	23/232	456/18986	0.0504385964912281	4.12770341802783	7.51921691783691	1.01731359932882e-08	3.15219779038408e-07	1.57446933107412e-07	VEGFA/MMP2/RHOA/THRA/MMP13/MMP14/AHSG/IGF2/LTF/COL1A2/COL1A1/COL2A1/COL6A1/COL11A1/COL5A2/TNF/PPP3CA/NPR2/HGF/ALOX5/BCL2/ALOX15/PTGS2	23
BP	GO:0030522	intracellular receptor signaling pathway	21/232	384/18986	0.0546875	4.47541756465517	7.65235521239704	1.1416509424784e-08	3.51201397844434e-07	1.754191414077e-07	NR4A2/NR4A3/SKP2/RHOA/ESR1/RORA/IKBKB/THRA/HSPA1A/ESR2/XIAP/SMARCA4/NR4A1/THRB/HSPA8/TNF/HAVCR2/HNF4A/AHR/AR/ALOX15	21
BP	GO:0002064	epithelial cell development	16/232	219/18986	0.0730593607305936	5.97890096047866	8.24252845719007	1.25245052302594e-08	3.8253417403278e-07	1.91069331670649e-07	VEGFA/KDR/NTRK1/PDE4D/ICAM1/EDNRA/ESR1/IKBKB/FLNA/COL18A1/COL27A1/LAMB2/B4GALT1/TNF/AR/PLEC	16
BP	GO:0061138	morphogenesis of a branching epithelium	15/232	190/18986	0.0789473684210526	6.46075317604356	8.4139313971562	1.27706732290777e-08	3.87286515798129e-07	1.93443045776772e-07	VEGFA/KDR/DDR1/EDNRA/ESR1/MMP14/LAMA1/COL4A1/LAMA5/PDGFA/NRP1/TNF/HGF/AR/BCL2	15
BP	GO:0048771	tissue remodeling	15/232	191/18986	0.0785340314136126	6.42692724318469	8.38401130299074	1.37104177371092e-08	4.12857367914639e-07	2.06215252695289e-07	MMP2/PRKCA/EDNRA/MMP14/CYP1A1/TP53/FLNA/MDM2/IL12B/COL6A1/LIPA/PPP3CA/PLG/NPR2/NPR3	15
BP	GO:0002819	regulation of adaptive immune response	16/232	221/18986	0.0723981900452489	5.92479325947886	8.19053354885026	1.42501602517521e-08	4.26109686968476e-07	2.1283456128675e-07	IL1R1/PRKCQ/EPHB2/IL18R1/BRD4/IL12B/HSPA8/MICA/HLA-A/TNFSF13/CLEC7A/TNF/HAVCR2/PRKCZ/AHR/ALOX15	16
BP	GO:2000573	positive regulation of DNA biosynthetic process	9/232	53/18986	0.169811320754717	13.8967143786597	10.4570608788161	1.4446131245832e-08	4.2896984171651e-07	2.14263160071587e-07	VEGFA/CCNA2/PDGFRB/ATM/ATR/CYP1B1/HTR2A/TNF/HGF	9
BP	GO:0050867	positive regulation of cell activation	21/232	391/18986	0.0537084398976982	4.39529499955904	7.54518927144847	1.56299469593544e-08	4.60921746194479e-07	2.30222594414011e-07	NR4A3/RHOA/PRKCQ/MMP8/SMARCA4/MMP14/EPHB2/FLNA/BRD4/IGF2/IL12B/KLRK1/HLA-A/TNFSF13/CLEC7A/FCGR3A/TNF/PPP3CA/HAVCR2/PRKCZ/BCL2	21
BP	GO:0044843	cell cycle G1/S phase transition	18/232	287/18986	0.0627177700348432	5.13258440466178	7.84613592241994	1.65011894676626e-08	4.83281412080309e-07	2.41390868276044e-07	CDC7/CDK2/CCNA2/SKP2/ITGB1/INHBA/ATM/CDK1/CDKN1B/ADAMTS1/SMARCA4/CYP1A1/TP53/CDKN2A/MDM2/HSPA8/PPP3CA/BCL2	18
BP	GO:2000117	negative regulation of cysteine-type endopeptidase activity	9/232	54/18986	0.166666666666667	13.639367816092	10.3449005919188	1.71525391961668e-08	4.98940527910267e-07	2.4921233103489e-07	VEGFA/SNCA/MMP9/XIAP/PLAUR/LTF/RAF1/TNF/PTGS2	9
BP	GO:0044403	biological process involved in symbiotic interaction	19/232	322/18986	0.0590062111801242	4.82884450631827	7.70718244609458	1.746850726742e-08	5.04698223483025e-07	2.52088202315755e-07	DDB1/ITGB1/ICAM1/ITGB7/EEF1A1/CXCL8/HSPA1A/CDK1/SMARCA4/BRD4/LTF/F2/ANPEP/HTR2A/PPIA/HSPA8/PF4/NRP1/PLG	19
BP	GO:0042692	muscle cell differentiation	22/232	432/18986	0.0509259259259259	4.16758461047254	7.40719297030065	1.82370370811621e-08	5.23366245362746e-07	2.61412562611642e-07	VEGFA/PDGFRB/PDGFRA/MYH9/ITGB1/EDNRA/RORA/CHUK/CDK1/MMP14/LMNA/MYH7/MDM2/IGF2/LAMA1/COL6A1/LAMB1/LAMB2/ADAMTS5/PPP3CA/BCL2/PLEC	22
BP	GO:0050954	sensory perception of mechanical stimulus	15/232	196/18986	0.076530612244898	6.26297501759325	8.23755432088917	1.9426096370624e-08	5.53773253871922e-07	2.76600347621025e-07	HEXA/NTRK1/KCNQ4/CDKN1B/COL1A1/COL2A1/COL6A1/COL11A1/COL11A2/COL4A3/THRB/HTR2A/TNF/NPR2/TRPA1	15
BP	GO:0030324	lung development	15/232	198/18986	0.0757575757575758	6.19971264367816	8.18038983180892	2.22652275674777e-08	6.30504060122747e-07	3.14926083892731e-07	VEGFA/KDR/PDGFRA/THRA/MMP14/CYP1A2/LAMA1/LTA4H/COL3A1/COL6A1/LAMA5/THRB/PDGFA/LIPA/TNF	15
BP	GO:0051054	positive regulation of DNA metabolic process	18/232	295/18986	0.0610169491525424	4.99339567504383	7.6884610727123	2.52053628384277e-08	7.09066654586296e-07	3.5416676730727e-07	VEGFA/CDC7/CDK2/CCNA2/SKP2/PDGFRB/PRKCD/PRKCQ/ATM/ATR/CDK1/CDKN1B/SMARCA4/CYP1B1/HTR2A/TNFSF13/TNF/HGF	18
BP	GO:0071674	mononuclear cell migration	16/232	231/18986	0.0692640692640693	5.66830870279146	7.93979629287176	2.66180937854683e-08	7.39342002014853e-07	3.69288789840022e-07	MMP2/RHOA/ITGAL/ICAM1/ITGB7/MMP14/CXCR1/B4GALT1/PF4/KLRK1/FLT1/TNF/CXCR2/PLG/ALOX5/PLEC	16
BP	GO:0031639	plasminogen activation	7/232	27/18986	0.259259259259259	21.2167943805875	11.6919998244976	2.68002830477788e-08	7.39342002014853e-07	3.69288789840022e-07	CPB2/PLAU/PLAUR/FGA/FGB/FGG/PLAT	7
BP	GO:0042759	long-chain fatty acid biosynthetic process	7/232	27/18986	0.259259259259259	21.2167943805875	11.6919998244976	2.68002830477788e-08	7.39342002014853e-07	3.69288789840022e-07	CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2D6/ALOX5/ALOX15	7
BP	GO:0072001	renal system development	19/232	332/18986	0.0572289156626506	4.68339738263398	7.53067609087497	2.85099604668846e-08	7.81465326643581e-07	3.90328676027725e-07	VEGFA/RHOA/PDGFRB/PDGFRA/EGR1/MMP9/EDNRA/ADAMTS1/COL4A1/COL4A3/COL4A4/LAMA5/LAMB2/HSPA8/TGFBR1/PDGFA/NRP1/PPP3CA/BCL2	19
BP	GO:0030323	respiratory tube development	15/232	202/18986	0.0742574257425743	6.07694605667463	8.06838347583139	2.91057722423317e-08	7.92715172663759e-07	3.95947783303325e-07	VEGFA/KDR/PDGFRA/THRA/MMP14/CYP1A2/LAMA1/LTA4H/COL3A1/COL6A1/LAMA5/THRB/PDGFA/LIPA/TNF	15
BP	GO:0050678	regulation of epithelial cell proliferation	21/232	406/18986	0.0517241379310345	4.23290725326992	7.3237876715264	2.99258358413987e-08	8.07447024964463e-07	4.03306093656859e-07	VEGFA/KDR/PRKCA/NR4A3/CPB2/NRP2/CDKN1B/IGF2/NR4A1/IL12B/COL4A3/LAMA5/LAMB1/TGFBR1/B4GALT1/NRP1/FLT1/GRN/TNF/AR/ALOX5	21
BP	GO:1901342	regulation of vasculature development	20/232	369/18986	0.0542005420054201	4.4355667694608	7.41240370437687	3.00243397963867e-08	8.07447024964463e-07	4.03306093656859e-07	VEGFA/KDR/NTRK1/PDE3B/PRKCA/ITGB1/SHC1/CXCL8/ADAMTS1/ERAP1/CYP1B1/COL4A2/COL4A3/TGFBR1/PF4/NRP1/FLT1/GRN/TNF/ALOX5	20
BP	GO:0051223	regulation of protein transport	22/232	446/18986	0.0493273542600897	4.0367635688882	7.21814966115907	3.21940369767308e-08	8.60385638203129e-07	4.29748033064386e-07	HMGCR/PDE8B/PRKCA/PRKCD/CDK1/CDKN2A/FLNA/MDM2/F2/FGA/FGB/FGG/IL12B/PPIA/HSPA8/INS/TNF/PPP3CA/HNF4A/PRKCZ/ALOX5/PTGS2	22
BP	GO:0032729	positive regulation of type II interferon production	10/232	77/18986	0.12987012987013	10.628078817734	9.41570960793643	3.27871539857889e-08	8.66627589584567e-07	4.328657819081e-07	PDE4D/PDE4B/IL1R1/IL18R1/IL12B/KLRK1/HLA-A/CLEC7A/TNF/HAVCR2	10
BP	GO:0002696	positive regulation of leukocyte activation	20/232	371/18986	0.0539083557951483	4.41165535830468	7.38113119374089	3.28329442265434e-08	8.66627589584567e-07	4.328657819081e-07	NR4A3/RHOA/PRKCQ/MMP8/SMARCA4/MMP14/EPHB2/BRD4/IGF2/IL12B/KLRK1/HLA-A/TNFSF13/CLEC7A/FCGR3A/TNF/PPP3CA/HAVCR2/PRKCZ/BCL2	20
BP	GO:0031099	regeneration	15/232	204/18986	0.0735294117647059	6.01736815415821	8.01350425604789	3.31985117358846e-08	8.70900835476335e-07	4.35000195751436e-07	MMP2/CCNA2/NR4A3/CPB2/CDK1/CDKN1B/FLNA/COL6A1/LAMB2/BRAF/GRN/TNF/PPP3CA/PLG/BCL2	15
BP	GO:0060537	muscle tissue development	22/232	447/18986	0.0492170022371365	4.02773277790635	7.20494200167701	3.34980132106503e-08	8.73399417614272e-07	4.36248195150253e-07	VEGFA/RHOA/PDGFRB/PDGFRA/ITGB1/EGR1/EDNRA/CDK1/LMNA/EPHB1/MYH7/IGF2/NR4A1/COL3A1/COL6A1/COL11A1/HSPA8/TGFBR1/PPP3CA/NPR2/BCL2/PLEC	22
BP	GO:0034614	cellular response to reactive oxygen species	13/232	148/18986	0.0878378378378378	7.18831547064306	8.40597790258975	3.44291221698784e-08	8.9223591756606e-07	4.45656707385539e-07	MMP2/PDGFRA/PRKCD/ATM/MMP3/CDK1/CYP1B1/MAP1LC3A/MDM2/HSPA8/TRPA1/HGF/MAPT	13
BP	GO:0035924	cellular response to vascular endothelial growth factor stimulus	10/232	78/18986	0.128205128205128	10.4918213969938	9.34278596355814	3.72100566039232e-08	9.58495193002262e-07	4.78752091625619e-07	VEGFA/KDR/PDGFRB/PDGFRA/ITGB1/NRP2/NR4A1/IL12B/NRP1/FLT1	10
BP	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	15/232	206/18986	0.0728155339805825	5.95894710411784	7.9593504916218	3.78081791837759e-08	9.66257628674725e-07	4.82629296583383e-07	IL1R1/PRKCQ/EPHB2/IL18R1/BRD4/IL12B/HSPA8/MICA/HLA-A/TNFSF13/CLEC7A/TNF/HAVCR2/PRKCZ/AHR	15
BP	GO:0045861	negative regulation of proteolysis	18/232	303/18986	0.0594059405940594	4.86155684533971	7.53637980435566	3.79633493024682e-08	9.66257628674725e-07	4.82629296583383e-07	VEGFA/SNCA/CPB2/MMP9/PLAU/XIAP/PLAUR/TP53/CDKN2A/MDM2/LTF/F2/COL6A3/RAF1/PLAT/INS/TNF/PTGS2	18
BP	GO:0014909	smooth muscle cell migration	11/232	100/18986	0.11	9.00198275862069	8.92339167600562	3.90071052627934e-08	9.86949006530795e-07	4.92964288870805e-07	NR4A3/PDGFRB/DDR1/PLAU/ADAMTS1/CYP1B1/MDM2/PLAT/PDGFA/NRP1/BCL2	11
BP	GO:0009636	response to toxic substance	17/232	270/18986	0.062962962962963	5.15265006385696	7.64368949443171	3.94924249577101e-08	9.93350641877462e-07	4.96161797146711e-07	MAOB/CHUK/CDK1/CYP1A1/CYP1B1/MDM2/BPHL/COL6A1/PON1/PON2/TNF/AHR/PTGS1/BCL2/PTGS2/SRD5A1/SLC6A4	17
BP	GO:0001763	morphogenesis of a branching structure	15/232	207/18986	0.072463768115942	5.93015992003998	7.93254027657907	4.03247268231047e-08	1.00835398769354e-06	5.03655713906307e-07	VEGFA/KDR/DDR1/EDNRA/ESR1/MMP14/LAMA1/COL4A1/LAMA5/PDGFA/NRP1/TNF/HGF/AR/BCL2	15
BP	GO:0048545	response to steroid hormone	19/232	340/18986	0.0558823529411765	4.57319979716024	7.39445646875831	4.16351265348138e-08	1.0350686108306e-06	5.16999215049799e-07	PDE3A/NR4A3/SKP2/RHOA/INHBA/MAOB/ESR1/HSPA1A/ESR2/SMARCA4/CYP1B1/MDM2/COL1A1/HSPA8/TNF/AR/BCL2/PTGS2/SRD5A1	19
BP	GO:0032943	mononuclear cell proliferation	18/232	305/18986	0.059016393442623	4.82967778405879	7.49919129859589	4.19679070694189e-08	1.03731081288344e-06	5.18119156944636e-07	PDE5A/PRKCD/PRKCQ/ATM/PLA2G5/TP53/CDKN2A/EPHB2/IGF2/IL12B/HLA-A/FCGR3A/LIPA/PPP3CA/HAVCR2/AHR/BCL2L1/BCL2	18
BP	GO:0070661	leukocyte proliferation	19/232	341/18986	0.0557184750733138	4.55978865406007	7.37772643327147	4.36187769180222e-08	1.0719189086291e-06	5.3540531377294e-07	PDE5A/PRKCD/PRKCQ/ATM/PLA2G5/TP53/CDKN2A/EPHB2/IGF2/IL12B/HLA-A/FCGR3A/LIPA/PPP3CA/HAVCR2/NPR3/AHR/BCL2L1/BCL2	19
BP	GO:0002699	positive regulation of immune effector process	17/232	272/18986	0.0625	5.11476293103448	7.6023576245964	4.39849904621897e-08	1.07474182409328e-06	5.36815312167115e-07	NR4A3/ITGB2/IL1R1/PLA2G5/EPHB2/IL18R1/BRD4/IL12B/HTR2A/HSPA8/KLRK1/MICA/HLA-A/TNFSF13/CLEC7A/TNF/PRKCZ	17
BP	GO:0019373	epoxygenase P450 pathway	6/232	18/18986	0.333333333333333	27.2787356321839	12.4060145243497	5.12418453343902e-08	1.23791034265453e-06	6.18315219646017e-07	CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP1B1/CYP2S1	6
BP	GO:0051917	regulation of fibrinolysis	6/232	18/18986	0.333333333333333	27.2787356321839	12.4060145243497	5.12418453343902e-08	1.23791034265453e-06	6.18315219646017e-07	CPB2/PLAU/PLAUR/F2/PLAT/PLG	6
BP	GO:0009746	response to hexose	15/232	211/18986	0.0710900473933649	5.81773982676908	7.82702886019508	5.19875751276622e-08	1.24887006317912e-06	6.2378941415746e-07	PDE8B/CPB2/ICAM1/EGR1/CDKN1B/SMARCA4/COL1A1/COL6A2/COL4A3/COL6A3/RAF1/TNF/PPP3CA/HNF4A/PTGS2	15
BP	GO:1903036	positive regulation of response to wounding	10/232	81/18986	0.123456790123457	10.1032354193274	9.13171355740601	5.37986250693581e-08	1.28313485917759e-06	6.40904098584838e-07	ITGB1/CPB2/PLAU/FLNA/F2/BRAF/PLAT/GRN/CLEC7A/PLG	10
BP	GO:0009743	response to carbohydrate	16/232	243/18986	0.065843621399177	5.38839222364127	7.65757675055741	5.40140960364748e-08	1.28313485917759e-06	6.40904098584838e-07	PDE8B/CPB2/ICAM1/EGR1/CDKN1B/SMARCA4/COL1A1/COL6A2/COL4A3/COL6A3/RAF1/CLEC7A/TNF/PPP3CA/HNF4A/PTGS2	16
BP	GO:0003018	vascular process in circulatory system	17/232	276/18986	0.0615942028985507	5.04063593203398	7.52089812920701	5.44025813384453e-08	1.2852234132773e-06	6.41947295933152e-07	VEGFA/MMP2/ITGA1/PDE3A/RHOA/ITGB1/EDNRA/FGA/FGB/FGG/HTR1A/HTR2A/INS/TNF/PTGS2/SLC6A4/PLEC	17
BP	GO:0043534	blood vessel endothelial cell migration	14/232	182/18986	0.0769230769230769	6.29509283819629	7.98337425229345	5.47581183717754e-08	1.28651491295446e-06	6.42592378116439e-07	VEGFA/KDR/PRKCA/RHOA/APOA1/MYH9/ITGB1/CYP1B1/EPHB4/NR4A1/NRP1/TNF/PLG/PTGS2	14
BP	GO:0010720	positive regulation of cell development	22/232	460/18986	0.0478260869565217	3.91390554722639	7.03664908644407	5.5551203072858e-08	1.29801608928711e-06	6.48337020620241e-07	VEGFA/NTRK2/PDE5A/PDE3A/PRKCA/RHOA/ITGB1/PRKCH/SMARCA4/MMP14/EPHB2/BRD4/IL12B/BRAF/PF4/NRP1/CLEC7A/TNF/PPP3CA/PRKCZ/MAPT/BCL2	22
BP	GO:0030574	collagen catabolic process	8/232	45/18986	0.177777777777778	14.5486590038314	10.120534616227	6.43327692264329e-08	1.49503761528384e-06	7.46745931123755e-07	MMP2/MMP1/ITGB1/MMP9/MMP8/MMP13/MMP3/MMP14	8
BP	GO:0071478	cellular response to radiation	14/232	185/18986	0.0756756756756757	6.19301025163094	7.89435962736315	6.72235474489686e-08	1.55377237238805e-06	7.76082946082261e-07	MMP2/MMP1/DDB1/EGR1/MMP9/PRKCD/ATM/ATR/MMP3/TP53/MDM2/POLD3/TNF/BCL2L1	14
BP	GO:0002274	myeloid leukocyte activation	16/232	247/18986	0.0647773279352227	5.30113081111266	7.56763643374842	6.77394046895551e-08	1.55727792716418e-06	7.77833911234337e-07	SNCA/NR4A3/ITGB2/PRKCD/RORA/PLA2G2A/ATM/MMP8/CXCL8/PLA2G10/GRN/FCGR3A/TNF/CXCR2/HAVCR2/MAPT	16
BP	GO:0048754	branching morphogenesis of an epithelial tube	13/232	158/18986	0.0822784810126582	6.7333587952859	8.0489254867062	7.49334333072245e-08	1.71345112738873e-06	8.55839775853411e-07	VEGFA/KDR/DDR1/EDNRA/ESR1/MMP14/LAMA1/COL4A1/LAMA5/NRP1/TNF/AR/BCL2	13
BP	GO:0034284	response to monosaccharide	15/232	218/18986	0.0688073394495413	5.63093166719393	7.64874107545056	7.99828126870751e-08	1.81918354813794e-06	9.08651326663356e-07	PDE8B/CPB2/ICAM1/EGR1/CDKN1B/SMARCA4/COL1A1/COL6A2/COL4A3/COL6A3/RAF1/TNF/PPP3CA/HNF4A/PTGS2	15
BP	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	12/232	133/18986	0.0902255639097744	7.38371791547835	8.21696831230322	8.70160244557918e-08	1.96868000303156e-06	9.83322270235597e-07	IL1R1/PRKCQ/IL18R1/BRD4/IL12B/HSPA8/MICA/HLA-A/TNFSF13/CLEC7A/TNF/PRKCZ	12
BP	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	8/232	47/18986	0.170212765957447	13.929567131328	9.87089948851694	9.18987668252342e-08	2.0682059312879e-06	1.03303378331524e-06	VEGFA/SNCA/MMP9/XIAP/PLAUR/RAF1/TNF/PTGS2	8
BP	GO:0001822	kidney development	18/232	322/18986	0.0559006211180124	4.57469479545941	7.19559776644017	9.53237440394618e-08	2.13242857139416e-06	1.0651119027519e-06	VEGFA/RHOA/PDGFRB/PDGFRA/EGR1/MMP9/EDNRA/ADAMTS1/COL4A3/COL4A4/LAMA5/LAMB2/HSPA8/TGFBR1/PDGFA/NRP1/PPP3CA/BCL2	18
BP	GO:0043542	endothelial cell migration	17/232	287/18986	0.0592334494773519	4.84744082662502	7.30476155432286	9.57498329531523e-08	2.13242857139416e-06	1.0651119027519e-06	VEGFA/KDR/PRKCA/RHOA/APOA1/MYH9/ITGB1/NRP2/CYP1B1/EPHB4/NR4A1/TGFBR1/NRP1/GRN/TNF/PLG/PTGS2	17
BP	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	7/232	32/18986	0.21875	17.9016702586207	10.6428149987955	9.64330663155634e-08	2.13651705474274e-06	1.06715403083871e-06	ICAM1/FGA/FGB/FGG/RAF1/HGF/BCL2L1	7
BP	GO:0045765	regulation of angiogenesis	19/232	360/18986	0.0527777777777778	4.31913314176245	7.07161262046563	1.02324657835313e-07	2.25536204589586e-06	1.12651508815979e-06	VEGFA/KDR/NTRK1/PDE3B/PRKCA/ITGB1/SHC1/CXCL8/ADAMTS1/ERAP1/CYP1B1/COL4A2/COL4A3/PF4/NRP1/FLT1/GRN/TNF/ALOX5	19
BP	GO:0061298	retina vasculature development in camera-type eye	6/232	20/18986	0.3	24.5508620689655	11.7202336847836	1.04820347495101e-07	2.29852208148231e-06	1.14807279388696e-06	PDGFRB/PDGFRA/CYP1B1/LAMA1/COL4A1/NRP1	6
BP	GO:0097267	omega-hydroxylase P450 pathway	5/232	11/18986	0.454545454545455	37.198275862069	13.3565924043604	1.13558023217042e-07	2.47741891467385e-06	1.23742872775177e-06	CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP1B1	5
BP	GO:0060541	respiratory system development	15/232	225/18986	0.0666666666666667	5.45574712643678	7.4780117009269	1.21035409241517e-07	2.61592058203876e-06	1.30660796143879e-06	VEGFA/KDR/PDGFRA/THRA/MMP14/CYP1A2/LAMA1/LTA4H/COL3A1/COL6A1/LAMA5/THRB/PDGFA/LIPA/TNF	15
BP	GO:0033238	regulation of amine metabolic process	7/232	33/18986	0.212121212121212	17.3591954022989	10.4612183239905	1.21130092433039e-07	2.61592058203876e-06	1.30660796143879e-06	NR4A2/ITGB2/MAOB/HTR1A/INS/HNF4A/SLC6A3	7
BP	GO:0042116	macrophage activation	11/232	112/18986	0.0982142857142857	8.03748460591133	8.30800656785601	1.27116727757196e-07	2.73141270296367e-06	1.36429431694975e-06	SNCA/ITGB2/RORA/ATM/MMP8/PLA2G10/GRN/FCGR3A/TNF/HAVCR2/MAPT	11
BP	GO:0019229	regulation of vasoconstriction	9/232	68/18986	0.132352941176471	10.8312626774848	9.03292663917385	1.37034318804604e-07	2.92979373604243e-06	1.4633822781818e-06	MMP2/RHOA/ITGB1/FGA/FGB/FGG/HTR1A/HTR2A/PTGS2	9
BP	GO:0002821	positive regulation of adaptive immune response	12/232	139/18986	0.0863309352517986	7.064996278839	7.98213669655942	1.41728524862322e-07	3.01508045926014e-06	1.50598154985939e-06	IL1R1/PRKCQ/IL18R1/BRD4/IL12B/HSPA8/MICA/HLA-A/TNFSF13/CLEC7A/TNF/PRKCZ	12
BP	GO:2000116	regulation of cysteine-type endopeptidase activity	13/232	167/18986	0.0778443113772455	6.37048317158786	7.75310493233758	1.43745078533507e-07	3.04284136539245e-06	1.51984765161274e-06	VEGFA/SNCA/MMP9/XIAP/PLAUR/CDKN2A/LTF/COL4A3/RAF1/CLEC7A/TNF/MAPT/PTGS2	13
BP	GO:0043086	negative regulation of catalytic activity	22/232	486/18986	0.0452674897119342	3.70451965375337	6.71776410669312	1.44691237105254e-07	3.04464488662272e-06	1.52074847987728e-06	VEGFA/SNCA/MMP9/PRKCD/PRKCH/XIAP/CDKN1B/PLAUR/TP53/CDKN2A/EPHB2/GLA/LTF/COL6A3/GZMA/RAF1/PPIA/KLRK1/INS/TNF/MAPT/PTGS2	22
BP	GO:0106070	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	6/232	21/18986	0.285714285714286	23.3817733990148	11.4137946748944	1.45254339773395e-07	3.04464488662272e-06	1.52074847987728e-06	PDE4A/PDE3A/PDE4D/PDE4B/PDE3B/PRKCA	6
BP	GO:0007517	muscle organ development	19/232	369/18986	0.0514905149051491	4.21378843098776	6.93390606833584	1.50233626298367e-07	3.13365359049668e-06	1.56520681776322e-06	RHOA/ITGB1/EGR1/EDNRA/LMNA/EPHB1/MYH7/IGF2/NR4A1/COL3A1/COL6A1/COL11A1/COL6A3/LAMA5/HSPA8/TGFBR1/PPP3CA/BCL2/PLEC	19
BP	GO:0014812	muscle cell migration	11/232	114/18986	0.0964912280701754	7.89647610405324	8.21434680966747	1.52565792893194e-07	3.16685111850144e-06	1.58178841992994e-06	NR4A3/PDGFRB/DDR1/PLAU/ADAMTS1/CYP1B1/MDM2/PLAT/PDGFA/NRP1/BCL2	11
BP	GO:0046651	lymphocyte proliferation	17/232	297/18986	0.0572390572390572	4.68422733077906	7.11760610318855	1.56435715472236e-07	3.23149333023807e-06	1.61407610827952e-06	PDE5A/PRKCD/PRKCQ/ATM/PLA2G5/TP53/CDKN2A/EPHB2/IGF2/IL12B/HLA-A/FCGR3A/LIPA/PPP3CA/HAVCR2/AHR/BCL2	17
BP	GO:0034644	cellular response to UV	10/232	91/18986	0.10989010989011	8.99298976885184	8.50078128515186	1.6546894519129e-07	3.40165966172095e-06	1.69907130462109e-06	MMP2/MMP1/DDB1/MMP9/PRKCD/ATR/MMP3/TP53/MDM2/POLD3	10
BP	GO:0001906	cell killing	16/232	264/18986	0.0606060606060606	4.95977011494253	7.20606464716693	1.68988407353043e-07	3.45738961646704e-06	1.72690747176693e-06	ICAM1/PLA2G2A/FCGR2A/CXCL8/LTF/F2/IL12B/GZMA/HSPA8/PF4/KLRK1/MICA/HLA-A/CLEC7A/FCGR3A/HAVCR2	16
BP	GO:0048705	skeletal system morphogenesis	15/232	232/18986	0.0646551724137931	5.2911340665874	7.31427790424717	1.80343978219277e-07	3.67214690888394e-06	1.8341750967765e-06	VEGFA/MMP2/PDGFRA/THRA/MMP13/MMP14/LTF/COL1A1/COL2A1/COL3A1/COL11A1/COL27A1/LAMA5/TGFBR1/NPR2	15
BP	GO:0060445	branching involved in salivary gland morphogenesis	6/232	22/18986	0.272727272727273	22.3189655172414	11.127941440594	1.97691540562222e-07	4.0062987082657e-06	2.00107825293464e-06	LAMA1/LAMA5/PDGFA/NRP1/TNF/HGF	6
BP	GO:0018958	phenol-containing compound metabolic process	11/232	117/18986	0.094017094017094	7.69400235779546	8.07805279034185	1.99220780497755e-07	4.01824555381321e-06	2.00704549965216e-06	NR4A2/SNCA/ITGB2/MAOA/EDNRA/MAOB/CYP1A1/HTR1A/BCL2/SRD5A1/SLC6A3	11
BP	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	12/232	144/18986	0.0833333333333333	6.81968390804598	7.79685541196902	2.08883597095764e-07	4.19336272855158e-06	2.09451355822736e-06	VEGFA/SNCA/MMP9/XIAP/PLAUR/CDKN2A/COL4A3/RAF1/CLEC7A/TNF/MAPT/PTGS2	12
BP	GO:1903829	positive regulation of protein localization	22/232	497/18986	0.0442655935613682	3.6225282730868	6.58937159499342	2.125804675971e-07	4.24763588525795e-06	2.12162207946147e-06	VEGFA/SNCA/PRKCA/ITGB1/ITGB2/PRKCD/PRKCH/CDK1/CDKN2A/EPHB2/FLNA/MDM2/F2/FGA/FGB/FGG/PPIA/INS/TNF/PRKCZ/MAPT/PTGS2	22
BP	GO:2000278	regulation of DNA biosynthetic process	10/232	94/18986	0.106382978723404	8.70597945707997	8.33019451602244	2.25459166846538e-07	4.48401580202697e-06	2.23968983858813e-06	VEGFA/CCNA2/PDGFRB/ATM/ATR/CYP1B1/TP53/HTR2A/TNF/HGF	10
BP	GO:0032835	glomerulus development	9/232	72/18986	0.125	10.229525862069	8.72682534556922	2.26860115337642e-07	4.49099006103591e-06	2.24317336267093e-06	PDGFRB/PDGFRA/EGR1/EDNRA/COL4A3/COL4A4/LAMB2/PPP3CA/BCL2	9
BP	GO:0002009	morphogenesis of an epithelium	22/232	500/18986	0.044	3.60079310344828	6.55498451422049	2.35630522870377e-07	4.64311574098495e-06	2.3191575595634e-06	VEGFA/KDR/MMP2/RHOA/DDR1/ITGB1/EDNRA/ESR1/PLA2G10/MMP14/FLNA/LAMA1/COL4A1/COL5A1/LAMA5/PDGFA/NRP1/TNF/HGF/AR/CA2/BCL2	22
BP	GO:0007623	circadian rhythm	14/232	206/18986	0.0679611650485437	5.56168396384332	7.32172389378582	2.54600677654393e-07	4.97120362376902e-06	2.48303189223262e-06	NTRK1/NTRK2/DDB1/KCNA2/EGR1/RORA/CDK1/TP53/COL6A1/TNF/HNF4A/AHR/SLC6A4/DYRK1A	14
BP	GO:0042698	ovulation cycle	9/232	73/18986	0.123287671232877	10.0893953708077	8.65403307926835	2.56037110358511e-07	4.97120362376902e-06	2.48303189223262e-06	MMP2/PDGFRA/EGR1/INHBA/ESR1/ADAMTS1/CYP1B1/HSPA8/NPR2	9
BP	GO:1903317	regulation of protein maturation	9/232	73/18986	0.123287671232877	10.0893953708077	8.65403307926835	2.56037110358511e-07	4.97120362376902e-06	2.48303189223262e-06	MYH9/CPB2/PLAU/XIAP/PLAUR/MMP14/MDM2/FGA/PLAT	9
BP	GO:0006720	isoprenoid metabolic process	11/232	120/18986	0.0916666666666667	7.50165229885057	7.94651642725353	2.58093359325707e-07	4.97120362376902e-06	2.48303189223262e-06	HMGCR/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2S1/LIPA/SRD5A1	11
BP	GO:0032355	response to estradiol	11/232	120/18986	0.0916666666666667	7.50165229885057	7.94651642725353	2.58093359325707e-07	4.97120362376902e-06	2.48303189223262e-06	MMP2/CCNA2/ESR1/ESR2/CDKN1B/CYP1B1/COL1A1/HSPA8/PTGS2/SRD5A1/SLC6A4	11
BP	GO:0009266	response to temperature stimulus	13/232	176/18986	0.0738636363636364	6.04471982758621	7.47827316575287	2.64739804424753e-07	5.07635607049437e-06	2.53555375585473e-06	NTRK1/THRA/ATM/ATR/HSPA1A/EPHB1/HTR2A/HSPA8/MICA/LIPA/TRPA1/MAPT/PTGS2	13
BP	GO:2000241	regulation of reproductive process	14/232	207/18986	0.0676328502415459	5.53481592537065	7.29643876837633	2.70144010875316e-07	5.15685620760202e-06	2.57576220895684e-06	VEGFA/DDB1/PDE5A/PDE3A/MYH9/INHBA/ESR1/CDKN1B/PLA2G10/PLAT/B4GALT1/NPR2/AR/BCL2L1	14
BP	GO:0030595	leukocyte chemotaxis	15/232	240/18986	0.0625	5.11476293103448	7.13507381771865	2.794624818257e-07	5.29830665047493e-06	2.64641430599519e-06	VEGFA/MMP2/ITGA1/PDE4B/ITGB2/CXCL8/IL17RA/PPIA/CXCR1/PF4/KLRK1/FLT1/CXCR2/ALOX5/PLEC	15
BP	GO:0009308	amine metabolic process	11/232	121/18986	0.0909090909090909	7.43965517241379	7.903677850246	2.80882860872645e-07	5.29830665047493e-06	2.64641430599519e-06	NR4A2/SNCA/ITGB2/MAOA/EDNRA/MAOB/CYP1A1/HTR1A/INS/HNF4A/SLC6A3	11
BP	GO:0003158	endothelium development	12/232	148/18986	0.0810810810810811	6.63536812674744	7.6548747669897	2.81668782996724e-07	5.29830665047493e-06	2.64641430599519e-06	VEGFA/KDR/PDE4D/RHOA/ICAM1/EDNRA/IKBKB/COL18A1/COL27A1/NRP1/LIPA/TNF	12
BP	GO:0010543	regulation of platelet activation	8/232	54/18986	0.148148148148148	12.1238825031928	9.10452645781899	2.82510270418214e-07	5.29830665047493e-06	2.64641430599519e-06	PRKCA/PDGFRA/PRKCD/PRKCQ/FLNA/F2/HTR2A/PDGFA	8
BP	GO:0014706	striated muscle tissue development	20/232	424/18986	0.0471698113207547	3.86019843851659	6.62474317932602	2.86191042384299e-07	5.34389911456447e-06	2.66918696850261e-06	VEGFA/RHOA/PDGFRB/PDGFRA/ITGB1/EGR1/EDNRA/CDK1/LMNA/EPHB1/MYH7/IGF2/NR4A1/COL6A1/COL11A1/HSPA8/TGFBR1/PPP3CA/BCL2/PLEC	20
BP	GO:2000379	positive regulation of reactive oxygen species metabolic process	9/232	74/18986	0.121621621621622	9.95305219012116	8.58263382200349	2.8841875806247e-07	5.3620809107614e-06	2.67826846731694e-06	SNCA/PDGFRB/ITGB2/PRKCD/CYP1B1/TP53/F2/CLEC7A/MAPT	9
BP	GO:0051918	negative regulation of fibrinolysis	5/232	13/18986	0.384615384615385	31.4754641909814	12.2252103234842	3.10076181030872e-07	5.73976515189613e-06	2.86691533976595e-06	CPB2/PLAU/F2/PLAT/PLG	5
BP	GO:0044772	mitotic cell cycle phase transition	21/232	467/18986	0.0449678800856531	3.68000073838884	6.52209207272561	3.14347329989585e-07	5.79374647860115e-06	2.8938780968642e-06	DDB1/CDC7/CDK2/CCNA2/SKP2/ITGB1/INHBA/ATM/ATR/CDK1/CDKN1B/ADAMTS1/SMARCA4/CYP1A1/TP53/CDKN2A/MDM2/BRD4/HSPA8/PPP3CA/BCL2	21
BP	GO:0001936	regulation of endothelial cell proliferation	13/232	179/18986	0.0726256983240224	5.94341167405124	7.39087520720035	3.21826096678516e-07	5.90613042659799e-06	2.9500119727161e-06	VEGFA/KDR/PRKCA/NRP2/IGF2/NR4A1/IL12B/COL4A3/TGFBR1/NRP1/FLT1/TNF/ALOX5	13
BP	GO:0097529	myeloid leukocyte migration	15/232	243/18986	0.0617283950617284	5.05161770966369	7.06991809176161	3.27828010164579e-07	5.99056654471684e-06	2.99218638157414e-06	VEGFA/MMP2/ITGA1/PDE4B/ITGB2/IL1R1/CXCL8/MMP14/IL17RA/PPIA/CXCR1/B4GALT1/PF4/FLT1/CXCR2	15
BP	GO:0071711	basement membrane organization	7/232	38/18986	0.184210526315789	15.0750907441016	9.65970027398935	3.39719346420459e-07	6.18144649061227e-06	3.08752767698594e-06	ITGB1/LAMA1/COL3A1/COL4A1/COL6A1/LAMB1/LAMB2	7
BP	GO:0008584	male gonad development	12/232	151/18986	0.0794701986754967	6.50353962091802	7.55179332992386	3.50269995355067e-07	6.34641737346723e-06	3.16992783485919e-06	NTRK1/PDGFRA/INHBA/ESR1/MMP14/CYP1B1/FLNA/TGFBR1/AR/BCL2L1/BCL2/SRD5A1	12
BP	GO:0032609	type II interferon production	11/232	124/18986	0.0887096774193548	7.25966351501669	7.77804225616818	3.60297101655697e-07	6.47323700285614e-06	3.23327208871919e-06	PDE4D/PDE4B/IL1R1/INHBA/IL18R1/IL12B/KLRK1/HLA-A/CLEC7A/TNF/HAVCR2	11
BP	GO:0032649	regulation of type II interferon production	11/232	124/18986	0.0887096774193548	7.25966351501669	7.77804225616818	3.60297101655697e-07	6.47323700285614e-06	3.23327208871919e-06	PDE4D/PDE4B/IL1R1/INHBA/IL18R1/IL12B/KLRK1/HLA-A/CLEC7A/TNF/HAVCR2	11
BP	GO:0032944	regulation of mononuclear cell proliferation	15/232	245/18986	0.0612244897959184	5.0103800140746	7.02707399180678	3.64144858883933e-07	6.51499337484393e-06	3.25412868828672e-06	PDE5A/PRKCQ/ATM/PLA2G5/CDKN2A/EPHB2/IGF2/IL12B/HLA-A/FCGR3A/PPP3CA/HAVCR2/AHR/BCL2L1/BCL2	15
BP	GO:0042542	response to hydrogen peroxide	10/232	99/18986	0.101010101010101	8.26628352490421	8.06214833012779	3.68353603618727e-07	6.56283337114032e-06	3.27802395501051e-06	MMP2/PRKCD/CDK1/CYP1B1/MAP1LC3A/MDM2/COL1A1/HSPA8/TRPA1/BCL2	10
BP	GO:0046546	development of primary male sexual characteristics	12/232	152/18986	0.0789473684210526	6.46075317604356	7.51805321256345	3.76235852854476e-07	6.67545438508606e-06	3.33427624128295e-06	NTRK1/PDGFRA/INHBA/ESR1/MMP14/CYP1B1/FLNA/TGFBR1/AR/BCL2L1/BCL2/SRD5A1	12
BP	GO:0045446	endothelial cell differentiation	11/232	125/18986	0.088	7.20158620689655	7.73709218602382	3.90861090258701e-07	6.90628934688515e-06	3.44957438945152e-06	VEGFA/KDR/PDE4D/ICAM1/EDNRA/IKBKB/COL18A1/COL27A1/NRP1/LIPA/TNF	11
BP	GO:0006721	terpenoid metabolic process	10/232	100/18986	0.1	8.18362068965517	8.01079719855583	4.04947658991609e-07	7.12574563723507e-06	3.55918908422775e-06	CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2S1/LIPA/SRD5A1	10
BP	GO:0010811	positive regulation of cell-substrate adhesion	11/232	126/18986	0.0873015873015873	7.14443076081007	7.69659120935292	4.2369354805406e-07	7.42505578475066e-06	3.70868942623679e-06	VEGFA/KDR/APOA1/FLNA/FGA/FGB/FGG/BRAF/NRP1/PRKCZ/ALOX15	11
BP	GO:0006584	catecholamine metabolic process	8/232	57/18986	0.140350877192982	11.4857834240774	8.81813641529495	4.34752603957586e-07	7.55691924602698e-06	3.77455298857485e-06	NR4A2/SNCA/ITGB2/MAOA/EDNRA/MAOB/HTR1A/SLC6A3	8
BP	GO:0009712	catechol-containing compound metabolic process	8/232	57/18986	0.140350877192982	11.4857834240774	8.81813641529495	4.34752603957586e-07	7.55691924602698e-06	3.77455298857485e-06	NR4A2/SNCA/ITGB2/MAOA/EDNRA/MAOB/HTR1A/SLC6A3	8
BP	GO:0050679	positive regulation of epithelial cell proliferation	14/232	216/18986	0.0648148148148148	5.30419859514687	7.07602531599662	4.5350456519183e-07	7.84606143449625e-06	3.91897460750157e-06	VEGFA/KDR/PRKCA/NR4A3/NRP2/IGF2/NR4A1/LAMB1/TGFBR1/B4GALT1/NRP1/GRN/TNF/AR	14
BP	GO:0042178	xenobiotic catabolic process	6/232	25/18986	0.24	19.6406896551724	10.3729837754446	4.55056883946462e-07	7.84606143449625e-06	3.91897460750157e-06	CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6	6
BP	GO:0001659	temperature homeostasis	13/232	185/18986	0.0702702702702703	5.75065237651445	7.22189183297183	4.70093680964957e-07	8.07277341287613e-06	4.03221339538321e-06	VEGFA/FABP4/EGR1/THRA/SMARCA4/IL18R1/LNPEP/LAMA4/ADAMTS5/HTR2A/TNF/NPR3/PTGS2	13
BP	GO:0009214	cyclic nucleotide catabolic process	5/232	14/18986	0.357142857142857	29.2272167487685	11.7510819584719	4.77543081086317e-07	8.16789685890037e-06	4.07972594325952e-06	PDE5A/PDE4A/PDE4D/PDE4B/PDE8B	5
BP	GO:0060348	bone development	14/232	217/18986	0.0645161290322581	5.2797552836485	7.05229667558873	4.79588542744364e-07	8.17020162858526e-06	4.08087713662535e-06	KDR/RHOA/MMP13/MMP14/TP53/LTF/COL1A1/COL2A1/COL3A1/COL6A1/COL27A1/LIPA/NPR2/SRD5A1	14
BP	GO:0008210	estrogen metabolic process	7/232	40/18986	0.175	14.3213362068966	9.38039995213578	4.91540795326359e-07	8.30762229571348e-06	4.14951642902926e-06	PDGFRA/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2D6/CYP1B1	7
BP	GO:0052652	cyclic purine nucleotide metabolic process	7/232	40/18986	0.175	14.3213362068966	9.38039995213578	4.91540795326359e-07	8.30762229571348e-06	4.14951642902926e-06	PDE5A/PDE4A/PDE4D/PDE4B/PDE8B/RORA/NPR2	7
BP	GO:0045444	fat cell differentiation	15/232	251/18986	0.0597609561752988	4.89060997389751	6.90128631087761	4.95937513054957e-07	8.34893230638974e-06	4.17015007869253e-06	VEGFA/NR4A2/FABP4/NR4A3/PDGFRA/RORA/ERAP1/NR4A1/LAMB3/HTR2A/INS/TNF/NPR2/ALOX5/PTGS2	15
BP	GO:0031638	zymogen activation	8/232	58/18986	0.137931034482759	11.2877526753864	8.7273920453624	4.99045640580258e-07	8.36831042792621e-06	4.17982912172278e-06	CPB2/PLAU/PLAUR/MMP14/FGA/FGB/FGG/PLAT	8
BP	GO:0002705	positive regulation of leukocyte mediated immunity	12/232	158/18986	0.0759493670886076	6.21540811872545	7.32178690175458	5.71230977599629e-07	9.50533028908035e-06	4.74775125708828e-06	ITGB2/IL1R1/IL18R1/IL12B/HSPA8/KLRK1/MICA/HLA-A/TNFSF13/CLEC7A/TNF/PRKCZ	12
BP	GO:0048008	platelet-derived growth factor receptor signaling pathway	8/232	59/18986	0.135593220338983	11.0964348334307	8.63884135465898	5.71297914942388e-07	9.50533028908035e-06	4.74775125708828e-06	VEGFA/SNCA/NR4A3/PDGFRB/PDGFRA/PLAT/PDGFA/NRP1	8
BP	GO:0002443	leukocyte mediated immunity	21/232	485/18986	0.0432989690721649	3.54342339139708	6.31094312347963	5.82753707328601e-07	9.61063077093108e-06	4.80034706174466e-06	NR4A3/ICAM1/ITGB2/IL1R1/MASP2/PRKCD/FCGR2A/IL18R1/F2/IL12B/HSPA8/KLRK1/MICA/HLA-A/TNFSF13/CLEC7A/FCGR3A/TNF/HAVCR2/PRKCZ/AHR	21
BP	GO:0009187	cyclic nucleotide metabolic process	7/232	41/18986	0.170731707317073	13.9720353238015	9.24815464999336	5.86617079329517e-07	9.61063077093108e-06	4.80034706174466e-06	PDE5A/PDE4A/PDE4D/PDE4B/PDE8B/RORA/NPR2	7
BP	GO:0042417	dopamine metabolic process	7/232	41/18986	0.170731707317073	13.9720353238015	9.24815464999336	5.86617079329517e-07	9.61063077093108e-06	4.80034706174466e-06	NR4A2/SNCA/ITGB2/MAOA/MAOB/HTR1A/SLC6A3	7
BP	GO:0150077	regulation of neuroinflammatory response	7/232	41/18986	0.170731707317073	13.9720353238015	9.24815464999336	5.86617079329517e-07	9.61063077093108e-06	4.80034706174466e-06	MMP9/ATM/MMP8/MMP3/GRN/TNF/PTGS2	7
BP	GO:1903409	reactive oxygen species biosynthetic process	8/232	60/18986	0.133333333333333	10.9114942528736	8.55239356640213	6.52306245487985e-07	1.0646036281323e-05	5.3175145524111e-06	SNCA/RHOA/MAOB/CYP1A1/CYP1A2/INS/LIPA/ALOX5	8
BP	GO:0050890	cognition	17/232	329/18986	0.0516717325227964	4.22861859343884	6.57046527023519	6.60486684586718e-07	1.07385591760183e-05	5.36372816900721e-06	NTRK1/NTRK2/HMGCR/PDE8B/ITGB1/THRA/EPHB2/HTR2A/BRAF/MAN2B1/INS/TNF/PRKCZ/MAPT/PTGS2/SLC6A4/SLC6A3	17
BP	GO:0001558	regulation of cell growth	19/232	408/18986	0.0465686274509804	3.81099983096687	6.38401294707676	6.96437779691653e-07	1.12801816134906e-05	5.63425938992968e-06	VEGFA/PLAA/DDR1/INHBA/PRKCQ/HSPA1A/ESR2/CDKN1B/SMARCA4/MMP14/TP53/CDKN2A/F2/TGFBR1/NRP1/INS/HNF4A/MAPT/BCL2	19
BP	GO:0002703	regulation of leukocyte mediated immunity	15/232	258/18986	0.0581395348837209	4.75791900561347	6.759489620553	7.03022146366119e-07	1.13012131498553e-05	5.64476428562269e-06	ICAM1/ITGB2/IL1R1/IL18R1/IL12B/HSPA8/KLRK1/MICA/HLA-A/TNFSF13/CLEC7A/TNF/HAVCR2/PRKCZ/AHR	15
BP	GO:0033674	positive regulation of kinase activity	15/232	258/18986	0.0581395348837209	4.75791900561347	6.759489620553	7.03022146366119e-07	1.13012131498553e-05	5.64476428562269e-06	SNCA/PDE5A/RHOA/PDGFRB/PRKCD/TPX2/LTF/F2/NTRK3/PPIA/PDGFA/FLT1/INS/TNF/MAPT	15
BP	GO:0051345	positive regulation of hydrolase activity	17/232	331/18986	0.0513595166163142	4.20306802791958	6.53860150372801	7.18384808400967e-07	1.15049192536425e-05	5.74651202935368e-06	NTRK1/SNCA/PLAA/RHOA/APOA1/ITGB1/PSAP/PRKCD/HSPA1A/PLA2G5/CDKN2A/NTRK3/COL4A3/GRN/CLEC7A/TNF/MAPT	17
BP	GO:0002532	production of molecular mediator involved in inflammatory response	10/232	107/18986	0.0934579439252336	7.64824363519175	7.67028779687724	7.62967601964879e-07	1.21733189029919e-05	6.08036631730849e-06	PLA2G10/EPHB2/IL17RA/F2/GRN/INS/CLEC7A/LIPA/TNF/ALOX5	10
BP	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	7/232	43/18986	0.162790697674419	13.3221732157177	8.99703676139291	8.23538842447956e-07	1.30908999639683e-05	6.5386824939421e-06	APOA1/FLNA/FGA/FGB/FGG/BRAF/NRP1	7
BP	GO:0046683	response to organophosphorus	11/232	135/18986	0.0814814814814815	6.66813537675607	7.35092918822609	8.47671068209288e-07	1.34245981024552e-05	6.70535905417795e-06	PDE3A/PDE4D/CYP1B1/COL1A1/BRAF/NPR2/AHR/PTGS2/SRD5A1/SLC6A4/SLC6A3	11
BP	GO:0051251	positive regulation of lymphocyte activation	17/232	336/18986	0.0505952380952381	4.1405223727422	6.46002873192878	8.83808342790962e-07	1.39452563607902e-05	6.96541902320009e-06	RHOA/PRKCQ/SMARCA4/MMP14/EPHB2/BRD4/IGF2/IL12B/KLRK1/HLA-A/TNFSF13/CLEC7A/FCGR3A/PPP3CA/HAVCR2/PRKCZ/BCL2	17
BP	GO:0034698	response to gonadotropin	6/232	28/18986	0.214285714285714	17.5363300492611	9.73922110114736	9.38792358702602e-07	1.47043081531587e-05	7.34455251901901e-06	CCNA2/INHBA/EDNRA/CYP1B1/NPR2/SRD5A1	6
BP	GO:0071480	cellular response to gamma radiation	6/232	28/18986	0.214285714285714	17.5363300492611	9.73922110114736	9.38792358702602e-07	1.47043081531587e-05	7.34455251901901e-06	EGR1/ATM/ATR/TP53/MDM2/BCL2L1	6
BP	GO:0034113	heterotypic cell-cell adhesion	8/232	63/18986	0.126984126984127	10.391899288451	8.3048356873036	9.56768787380486e-07	1.49311800541568e-05	7.45787118553594e-06	APOA1/ITGB1/ITGB2/ITGB7/FGA/FGB/FGG/TNF	8
BP	GO:0042119	neutrophil activation	7/232	44/18986	0.159090909090909	13.0193965517241	8.87765826566893	9.69230408127777e-07	1.50706517278341e-05	7.52753492092348e-06	ITGB2/PRKCD/PLA2G2A/CXCL8/GRN/TNF/CXCR2	7
BP	GO:0072378	blood coagulation, fibrin clot formation	5/232	16/18986	0.3125	25.5738146551724	10.9370762921998	1.02129596025059e-06	1.582268668852e-05	7.9031636283312e-06	FLNA/FGA/FGB/FGG/F13A1	5
BP	GO:0051347	positive regulation of transferase activity	16/232	304/18986	0.0526315789473684	4.30716878402904	6.46522740745629	1.1161368072032e-06	1.72296064534328e-05	8.60589618778376e-06	SNCA/PDE5A/RHOA/APOA1/PDGFRB/PRKCD/TPX2/LTF/F2/NTRK3/PPIA/PDGFA/FLT1/INS/TNF/MAPT	16
BP	GO:0071214	cellular response to abiotic stimulus	17/232	342/18986	0.0497076023391813	4.06788162936076	6.36772709141092	1.12745021383048e-06	1.72794878650149e-05	8.63081110681778e-06	MMP2/MMP1/DDB1/EGR1/MMP9/PRKCD/ATM/ATR/MMP3/TP53/MDM2/COL1A1/POLD3/TNF/BCL2L1/PTGS2/PLEC	17
BP	GO:0104004	cellular response to environmental stimulus	17/232	342/18986	0.0497076023391813	4.06788162936076	6.36772709141092	1.12745021383048e-06	1.72794878650149e-05	8.63081110681778e-06	MMP2/MMP1/DDB1/EGR1/MMP9/PRKCD/ATM/ATR/MMP3/TP53/MDM2/COL1A1/POLD3/TNF/BCL2L1/PTGS2/PLEC	17
BP	GO:1990776	response to angiotensin	7/232	45/18986	0.155555555555556	12.7300766283525	8.76209568302413	1.13592207845171e-06	1.72854192436281e-05	8.6337737298315e-06	PRKCA/INHBA/PRKCD/COL3A1/PPP3CA/CA2/PTGS2	7
BP	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	7/232	45/18986	0.155555555555556	12.7300766283525	8.76209568302413	1.13592207845171e-06	1.72854192436281e-05	8.6337737298315e-06	INHBA/HSPA1A/COL2A1/PF4/TNF/BCL2L1/BCL2	7
BP	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	9/232	87/18986	0.103448275862069	8.46581450653983	7.7628241186037	1.16646990805283e-06	1.7687323854021e-05	8.83451826591714e-06	ICAM1/FGA/FGB/FGG/RAF1/TNF/HGF/BCL2L1/BCL2	9
BP	GO:0010039	response to iron ion	6/232	29/18986	0.206896551724138	16.9316290130797	9.54941387105545	1.17165981010425e-06	1.77032415123879e-05	8.842468866288e-06	SNCA/CYP1A1/MAP1LC3A/MDM2/BCL2/SLC6A3	6
BP	GO:0019216	regulation of lipid metabolic process	17/232	344/18986	0.0494186046511628	4.04423115477145	6.33742646379699	1.221264440224e-06	1.83877702337952e-05	9.1843793521664e-06	SNCA/PDE3B/PDE8B/APOA1/PSAP/EGR1/PRKCD/RORA/THRA/F2/HTR2A/PDGFA/INS/TNF/HNF4A/MAPT/PTGS2	17
BP	GO:0070663	regulation of leukocyte proliferation	15/232	270/18986	0.0555555555555556	4.54645593869732	6.52788161396577	1.24482743844627e-06	1.86767793922676e-05	9.32873452486608e-06	PDE5A/PRKCQ/ATM/PLA2G5/CDKN2A/EPHB2/IGF2/IL12B/HLA-A/FCGR3A/PPP3CA/HAVCR2/AHR/BCL2L1/BCL2	15
BP	GO:0042391	regulation of membrane potential	20/232	466/18986	0.0429184549356223	3.51228355779192	6.1072185332558	1.25398525698852e-06	1.8748394961129e-05	9.36450528682259e-06	KDR/NTRK2/SNCA/HTR3A/KCNA2/KCNQ2/HTR3B/CDKN2A/FLNA/LTF/COL6A1/LIPA/TNF/PPP3CA/NPR2/PRKCZ/MAPT/BCL2L1/BCL2/SLC6A4	20
BP	GO:0001655	urogenital system development	8/232	66/18986	0.121212121212121	9.91954022988506	8.07339511845388	1.37493834832096e-06	2.04140151993765e-05	1.01964543448217e-05	MMP2/PSAP/ESR1/CDKN1B/EPHB2/EPHB3/AR/SRD5A1	8
BP	GO:0001885	endothelial cell development	8/232	66/18986	0.121212121212121	9.91954022988506	8.07339511845388	1.37493834832096e-06	2.04140151993765e-05	1.01964543448217e-05	VEGFA/PDE4D/ICAM1/EDNRA/IKBKB/COL18A1/COL27A1/TNF	8
BP	GO:0033627	cell adhesion mediated by integrin	9/232	89/18986	0.101123595505618	8.27557148392096	7.65187772035297	1.41528425056552e-06	2.08681222600626e-05	1.04232731194099e-05	ITGA1/PDE3B/ITGB1/ITGAL/ICAM1/ITGB2/PLAU/ITGB7/CYP1B1	9
BP	GO:0046209	nitric oxide metabolic process	9/232	89/18986	0.101123595505618	8.27557148392096	7.65187772035297	1.41528425056552e-06	2.08681222600626e-05	1.04232731194099e-05	ESR1/RORA/CYP1A1/CYP1B1/GLA/KLRK1/CLEC7A/TNF/PTGS2	9
BP	GO:0003007	heart morphogenesis	15/232	274/18986	0.0547445255474453	4.48008431915429	6.45367782270599	1.49535430012227e-06	2.19729724650269e-05	1.09751270571463e-05	VEGFA/EDNRA/NRP2/ADAMTS1/TP53/EPHB4/FLNA/MYH7/MDM2/COL2A1/COL5A1/COL11A1/ADAMTS5/TGFBR1/NRP1	15
BP	GO:0070613	regulation of protein processing	8/232	67/18986	0.119402985074627	9.77148739063304	7.99951935441178	1.54507732295653e-06	2.26258583320621e-05	1.13012324739683e-05	MYH9/CPB2/PLAU/XIAP/PLAUR/MMP14/MDM2/PLAT	8
BP	GO:0009749	response to glucose	13/232	206/18986	0.0631067961165049	5.1644208235688	6.68409729594984	1.58749473194172e-06	2.31676705589857e-05	1.15718584915026e-05	PDE8B/CPB2/ICAM1/EGR1/CDKN1B/SMARCA4/COL1A1/COL6A2/COL4A3/COL6A3/RAF1/PPP3CA/HNF4A	13
BP	GO:0060041	retina development in camera-type eye	12/232	174/18986	0.0689655172413793	5.64387633769322	6.8444747046576	1.59410244129846e-06	2.31849729217423e-05	1.15805007282298e-05	NTRK2/PDE6A/PDE6C/PDGFRB/PDGFRA/SMARCA4/CYP1B1/LAMA1/COL4A1/LAMB2/THRB/NRP1	12
BP	GO:0050670	regulation of lymphocyte proliferation	14/232	240/18986	0.0583333333333333	4.77377873563218	6.54380101643016	1.59964807904264e-06	2.31867633423266e-05	1.15813950129439e-05	PDE5A/PRKCQ/ATM/PLA2G5/CDKN2A/EPHB2/IGF2/IL12B/HLA-A/FCGR3A/PPP3CA/HAVCR2/AHR/BCL2	14
BP	GO:0070555	response to interleukin-1	10/232	116/18986	0.0862068965517241	7.05484542211653	7.27525871963999	1.60952525855857e-06	2.32511148837718e-05	1.1613537516413e-05	MMP2/SNCA/PRKCA/IL1R1/EGR1/RORA/IKBKB/CXCL8/FGB/FGG	10
BP	GO:1903037	regulation of leukocyte cell-cell adhesion	18/232	392/18986	0.0459183673469388	3.75778501055595	6.13648058186495	1.6861728892751e-06	2.42146605612374e-05	1.20948122393655e-05	PDE5A/NR4A3/RHOA/ITGB2/PRKCQ/SMARCA4/PLA2G5/CDKN2A/BRD4/IGF2/IL12B/KLRK1/HLA-A/TNF/PPP3CA/HAVCR2/PRKCZ/ALOX5	18
BP	GO:0046661	male sex differentiation	12/232	175/18986	0.0685714285714286	5.61162561576355	6.81662593903872	1.69321410379092e-06	2.42146605612374e-05	1.20948122393655e-05	NTRK1/PDGFRA/INHBA/ESR1/MMP14/CYP1B1/FLNA/TGFBR1/AR/BCL2L1/BCL2/SRD5A1	12
BP	GO:0071897	DNA biosynthetic process	12/232	175/18986	0.0685714285714286	5.61162561576355	6.81662593903872	1.69321410379092e-06	2.42146605612374e-05	1.20948122393655e-05	VEGFA/CCNA2/PDGFRB/ATM/ATR/RPA1/CYP1B1/TP53/HTR2A/POLD3/TNF/HGF	12
BP	GO:0051146	striated muscle cell differentiation	16/232	314/18986	0.0509554140127389	4.16999780364595	6.29985717118529	1.7037821463824e-06	2.42725757583967e-05	1.21237398980323e-05	VEGFA/PDGFRB/PDGFRA/MYH9/ITGB1/CHUK/CDK1/MMP14/LMNA/MYH7/IGF2/COL6A1/ADAMTS5/PPP3CA/BCL2/PLEC	16
BP	GO:2001057	reactive nitrogen species metabolic process	9/232	91/18986	0.0989010989010989	8.09369079196665	7.54435019571736	1.70861676877395e-06	2.42725757583967e-05	1.21237398980323e-05	ESR1/RORA/CYP1A1/CYP1B1/GLA/KLRK1/CLEC7A/TNF/PTGS2	9
BP	GO:0046434	organophosphate catabolic process	14/232	242/18986	0.0578512396694215	4.73432601880878	6.50266099091226	1.76419582450858e-06	2.49791435284725e-05	1.24766585149108e-05	PDE5A/PDE4A/PDE4D/PDE4B/PDE8B/PRKCD/PLA2G5/PLA2G10/ALDOA/COL6A1/HTR2A/PON1/INS/LIPA	14
BP	GO:0034612	response to tumor necrosis factor	14/232	243/18986	0.0576131687242798	4.71484319568611	6.4822594329658	1.85200870398813e-06	2.6135938014037e-05	1.30544577397669e-05	FABP4/APOA1/RORA/IKBKB/CHUK/MMP8/CXCL8/HSPA1A/XIAP/CYP1B1/TP53/COL1A1/TNF/PTGS2	14
BP	GO:0042053	regulation of dopamine metabolic process	5/232	18/18986	0.277777777777778	22.7322796934866	10.2596632234631	1.96369166630648e-06	2.75303133282837e-05	1.37509245588813e-05	NR4A2/ITGB2/MAOB/HTR1A/SLC6A3	5
BP	GO:0042069	regulation of catecholamine metabolic process	5/232	18/18986	0.277777777777778	22.7322796934866	10.2596632234631	1.96369166630648e-06	2.75303133282837e-05	1.37509245588813e-05	NR4A2/ITGB2/MAOB/HTR1A/SLC6A3	5
BP	GO:0014910	regulation of smooth muscle cell migration	9/232	93/18986	0.0967741935483871	7.91963292547275	7.44005945061395	2.05293621772994e-06	2.85456173677587e-05	1.42580517057709e-05	NR4A3/PDGFRB/PLAU/ADAMTS1/CYP1B1/MDM2/PDGFA/NRP1/BCL2	9
BP	GO:0001774	microglial cell activation	7/232	49/18986	0.142857142857143	11.6908866995074	8.33409630684409	2.06281472559342e-06	2.85456173677587e-05	1.42580517057709e-05	SNCA/ITGB2/ATM/MMP8/GRN/TNF/MAPT	7
BP	GO:0035272	exocrine system development	7/232	49/18986	0.142857142857143	11.6908866995074	8.33409630684409	2.06281472559342e-06	2.85456173677587e-05	1.42580517057709e-05	IGF2/LAMA1/LAMA5/PDGFA/NRP1/TNF/HGF	7
BP	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	7/232	49/18986	0.142857142857143	11.6908866995074	8.33409630684409	2.06281472559342e-06	2.85456173677587e-05	1.42580517057709e-05	ICAM1/FGA/FGB/FGG/RAF1/HGF/BCL2L1	7
BP	GO:0072577	endothelial cell apoptotic process	8/232	70/18986	0.114285714285714	9.35270935960591	7.78689062581955	2.16704975863903e-06	2.98041997628645e-05	1.48866922649924e-05	KDR/ICAM1/FGA/FGB/FGG/COL4A3/BRAF/TNF	8
BP	GO:1903318	negative regulation of protein maturation	6/232	32/18986	0.1875	15.3442887931034	9.03245712277634	2.16770489388467e-06	2.98041997628645e-05	1.48866922649924e-05	CPB2/PLAU/XIAP/MDM2/FGA/PLAT	6
BP	GO:1903039	positive regulation of leukocyte cell-cell adhesion	15/232	284/18986	0.0528169014084507	4.32233487129675	6.27423651057022	2.33091339736864e-06	3.19454669459881e-05	1.59562189043892e-05	NR4A3/RHOA/ITGB2/PRKCQ/SMARCA4/BRD4/IGF2/IL12B/KLRK1/HLA-A/TNF/PPP3CA/HAVCR2/PRKCZ/ALOX5	15
BP	GO:0014074	response to purine-containing compound	11/232	150/18986	0.0733333333333333	6.00132183908046	6.8397216602044	2.40203259282565e-06	3.28149883927235e-05	1.63905301188607e-05	PDE3A/PDE4D/CYP1B1/COL1A1/BRAF/NPR2/AHR/PTGS2/SRD5A1/SLC6A4/SLC6A3	11
BP	GO:0019058	viral life cycle	16/232	323/18986	0.0495356037151703	4.05380591438027	6.15678945735336	2.4569591425507e-06	3.34584627183019e-05	1.67119346303566e-05	DDB1/ITGB1/ICAM1/ITGB7/EEF1A1/CXCL8/HSPA1A/CDK1/LTF/ANPEP/HTR2A/PPIA/HSPA8/NRP1/TNF/BCL2	16
BP	GO:0071482	cellular response to light stimulus	10/232	122/18986	0.0819672131147541	6.70788581119276	7.03461988076806	2.55130197123918e-06	3.46329118381547e-05	1.7298552045595e-05	MMP2/MMP1/DDB1/MMP9/PRKCD/ATR/MMP3/TP53/MDM2/POLD3	10
BP	GO:0010743	regulation of macrophage derived foam cell differentiation	6/232	33/18986	0.181818181818182	14.8793103448276	8.87540567449041	2.62249929420726e-06	3.53747854322721e-05	1.76691053227512e-05	PRKCH/PLA2G2A/PLA2G5/PLA2G10/ABCA1/PF4	6
BP	GO:0045907	positive regulation of vasoconstriction	6/232	33/18986	0.181818181818182	14.8793103448276	8.87540567449041	2.62249929420726e-06	3.53747854322721e-05	1.76691053227512e-05	RHOA/FGA/FGB/FGG/HTR2A/PTGS2	6
BP	GO:0010744	positive regulation of macrophage derived foam cell differentiation	5/232	19/18986	0.263157894736842	21.5358439201452	9.96075758049647	2.63853542750651e-06	3.54791744906221e-05	1.77212458868279e-05	PRKCH/PLA2G2A/PLA2G5/PLA2G10/PF4	5
BP	GO:0006631	fatty acid metabolic process	18/232	405/18986	0.0444444444444444	3.63716475095785	5.96667756489018	2.67051857219734e-06	3.57966690116484e-05	1.78798290149758e-05	SNCA/PLAA/PLA2G5/PLA2G10/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2S1/INS/LIPA/ALOX5/PTGS1/ALOX15/PTGS2	18
BP	GO:0014911	positive regulation of smooth muscle cell migration	7/232	51/18986	0.137254901960784	11.2324205544287	8.13828982458636	2.72314730708876e-06	3.62746974614066e-05	1.81185961176688e-05	NR4A3/PDGFRB/ADAMTS1/CYP1B1/MDM2/NRP1/BCL2	7
BP	GO:0048013	ephrin receptor signaling pathway	7/232	51/18986	0.137254901960784	11.2324205544287	8.13828982458636	2.72314730708876e-06	3.62746974614066e-05	1.81185961176688e-05	NTRK1/MMP2/MMP9/EPHB2/EPHB3/EPHB1/EPHB4	7
BP	GO:0033002	muscle cell proliferation	14/232	252/18986	0.0555555555555556	4.54645593869732	6.30350233896251	2.83611822785776e-06	3.76622408146577e-05	1.88116504881445e-05	MMP2/NR4A3/PDGFRB/MMP9/CDK1/CDKN1B/ADAMTS1/EPHB1/MDM2/IL12B/TGFBR1/TNF/HGF/PTGS2	14
BP	GO:0033555	multicellular organismal response to stress	9/232	97/18986	0.0927835051546392	7.59305012442233	7.2405256886208	2.92408308985087e-06	3.87101526074375e-05	1.93350646547414e-05	NTRK1/NR4A2/PDE8B/EPHB2/COL6A1/HTR1A/PPP3CA/TRPA1/BCL2	9
BP	GO:0044706	multi-multicellular organism process	13/232	218/18986	0.0596330275229358	4.88014077823474	6.40868712429048	2.97721183744884e-06	3.92918451139853e-05	1.96256101955286e-05	VEGFA/MMP2/DDR1/MMP9/ESR1/CYP1A1/LNPEP/B4GALT1/HAVCR2/AR/BCL2/PTGS2/SLC6A4	13
BP	GO:0061448	connective tissue development	15/232	290/18986	0.0517241379310345	4.23290725326992	6.17049823193457	3.013549915333e-06	3.96490444245043e-05	1.98040251925851e-05	PDGFRB/EGR1/THRA/MMP13/COL1A1/COL2A1/COL3A1/COL5A1/COL6A1/COL11A1/COL27A1/COL11A2/TGFBR1/LIPA/NPR2	15
BP	GO:0002269	leukocyte activation involved in inflammatory response	7/232	52/18986	0.134615384615385	11.0164124668435	8.0444252936382	3.11428831052222e-06	4.07238434733731e-05	2.0340869087557e-05	SNCA/ITGB2/ATM/MMP8/GRN/TNF/MAPT	7
BP	GO:0036230	granulocyte activation	7/232	52/18986	0.134615384615385	11.0164124668435	8.0444252936382	3.11428831052222e-06	4.07238434733731e-05	2.0340869087557e-05	ITGB2/PRKCD/PLA2G2A/CXCL8/GRN/TNF/CXCR2	7
BP	GO:0007435	salivary gland morphogenesis	6/232	34/18986	0.176470588235294	14.4416835699797	8.72505030282386	3.15211549942497e-06	4.08434109917239e-05	2.04005910349583e-05	LAMA1/LAMA5/PDGFA/NRP1/TNF/HGF	6
BP	GO:0060055	angiogenesis involved in wound healing	6/232	34/18986	0.176470588235294	14.4416835699797	8.72505030282386	3.15211549942497e-06	4.08434109917239e-05	2.04005910349583e-05	VEGFA/KDR/B4GALT1/TNF/NPR2/ALOX5	6
BP	GO:0002768	immune response-regulating cell surface receptor signaling pathway	17/232	369/18986	0.046070460704607	3.77023175404168	5.97691079625378	3.15925871718977e-06	4.08434109917239e-05	2.04005910349583e-05	PDE4D/PDE4B/NR4A3/PRKCD/PRKCH/PRKCQ/IKBKB/CHUK/FCGR2A/LTF/BRAF/KLRK1/HLA-A/CLEC7A/FCGR3A/LIPA/BCL2	17
BP	GO:0016032	viral process	19/232	452/18986	0.0420353982300885	3.44001754653647	5.83955730776402	3.1616391576849e-06	4.08434109917239e-05	2.04005910349583e-05	DDB1/ITGB1/ICAM1/ITGB7/EEF1A1/CXCL8/HSPA1A/CDK1/SMARCA4/TP53/BRD4/LTF/ANPEP/HTR2A/PPIA/HSPA8/NRP1/TNF/BCL2	19
BP	GO:0001952	regulation of cell-matrix adhesion	10/232	125/18986	0.08	6.54689655172414	6.92030208647282	3.18028895727787e-06	4.09605891003619e-05	2.04591195127355e-05	VEGFA/KDR/RHOA/DDR1/PLAU/MMP14/CDKN2A/NRP1/PRKCZ/BCL2	10
BP	GO:0071356	cellular response to tumor necrosis factor	13/232	221/18986	0.0588235294117647	4.81389452332657	6.34297307505415	3.46077817530631e-06	4.44393017345639e-05	2.2196677470196e-05	FABP4/APOA1/RORA/IKBKB/CHUK/MMP8/CXCL8/HSPA1A/XIAP/CYP1B1/TP53/COL1A1/TNF	13
BP	GO:0043171	peptide catabolic process	5/232	20/18986	0.25	20.4590517241379	9.68391869577137	3.48310712084365e-06	4.44590031305297e-05	2.22065179833205e-05	ERAP1/ANPEP/LNPEP/ERAP2/LTA4H	5
BP	GO:0072376	protein activation cascade	5/232	20/18986	0.25	20.4590517241379	9.68391869577137	3.48310712084365e-06	4.44590031305297e-05	2.22065179833205e-05	FLNA/FGA/FGB/FGG/F13A1	5
BP	GO:0097530	granulocyte migration	11/232	156/18986	0.0705128205128205	5.7705017683466	6.65431779113441	3.51998214635863e-06	4.47959632673497e-05	2.23748238563962e-05	VEGFA/ITGA1/PDE4B/ITGB2/IL1R1/CXCL8/IL17RA/PPIA/CXCR1/PF4/CXCR2	11
BP	GO:0010332	response to gamma radiation	7/232	53/18986	0.132075471698113	10.8085556278465	7.95308481851515	3.55119335565415e-06	4.5059058720407e-05	2.25062355727699e-05	EGR1/ATM/ATR/TP53/MDM2/BCL2L1/BCL2	7
BP	GO:0051222	positive regulation of protein transport	14/232	257/18986	0.0544747081712062	4.45800348852811	6.20779020397977	3.56431748353146e-06	4.50917797620725e-05	2.25225791780919e-05	PRKCA/PRKCD/CDK1/FLNA/MDM2/F2/FGA/FGB/FGG/PPIA/INS/TNF/PRKCZ/PTGS2	14
BP	GO:0009612	response to mechanical stimulus	13/232	222/18986	0.0585585585585586	4.79221031376204	6.32133093983236	3.63677127000572e-06	4.58726665207801e-05	2.29126188692489e-05	NTRK1/MMP2/ATR/MMP14/COL1A1/COL6A1/COL11A1/HTR2A/RAF1/TNF/TRPA1/PTGS2/PLEC	13
BP	GO:1901136	carbohydrate derivative catabolic process	14/232	258/18986	0.0542635658914729	4.44072440523924	6.18894150450199	3.72849016681144e-06	4.68912469214286e-05	2.34213825029734e-05	HEXA/PDE5A/PDE4A/PDE4D/PDE4B/PDE8B/PRKCD/ALDOA/GLA/COL6A1/HTR2A/INS/MANBA/LIPA	14
BP	GO:0007409	axonogenesis	19/232	459/18986	0.0413943355119826	3.38755540530388	5.75916588416743	3.94886896788104e-06	4.95171956207019e-05	2.47329993388814e-05	VEGFA/NTRK1/NTRK2/NR4A2/ITGB1/EDNRA/PRKCQ/NRP2/PLA2G10/EPHB2/EPHB3/EPHB1/GLA/LAMB2/BRAF/NRP1/NPR2/MAPT/BCL2	19
BP	GO:0008217	regulation of blood pressure	12/232	190/18986	0.0631578947368421	5.16860254083485	6.42298501138401	3.99023332187003e-06	4.98895838722697e-05	2.49190009543684e-05	RHOA/EDNRA/ERAP1/LNPEP/ERAP2/COL1A2/TNF/NPR2/NPR3/AR/PTGS1/PTGS2	12
BP	GO:0001836	release of cytochrome c from mitochondria	7/232	54/18986	0.12962962962963	10.6083971902937	7.86415232371917	4.03801849600844e-06	5.01935089794537e-05	2.50708063904563e-05	MMP9/PLAUR/TP53/LMNA/HGF/BCL2L1/BCL2	7
BP	GO:0072538	T-helper 17 type immune response	7/232	54/18986	0.12962962962963	10.6083971902937	7.86415232371917	4.03801849600844e-06	5.01935089794537e-05	2.50708063904563e-05	PRKCQ/RORA/EPHB2/IL17RA/BRD4/IL12B/CLEC7A	7
BP	GO:0043549	regulation of kinase activity	19/232	460/18986	0.041304347826087	3.38019115442279	5.74780810183555	4.07476378514023e-06	5.05034491166946e-05	2.52256162320352e-05	SNCA/PDE5A/RHOA/PDGFRB/PRKCD/PRKCH/CDKN1B/CDKN2A/TPX2/EPHB2/LTF/F2/NTRK3/PPIA/PDGFA/FLT1/INS/TNF/MAPT	19
BP	GO:0009154	purine ribonucleotide catabolic process	10/232	129/18986	0.0775193798449612	6.34389200748463	6.77358468827859	4.22574947693331e-06	5.20729243901061e-05	2.60095425108378e-05	PDE5A/PDE4A/PDE4D/PDE4B/PDE8B/ALDOA/COL6A1/HTR2A/INS/LIPA	10
BP	GO:0071621	granulocyte chemotaxis	10/232	129/18986	0.0775193798449612	6.34389200748463	6.77358468827859	4.22574947693331e-06	5.20729243901061e-05	2.60095425108378e-05	VEGFA/ITGA1/PDE4B/ITGB2/CXCL8/IL17RA/PPIA/CXCR1/PF4/CXCR2	10
BP	GO:0061299	retina vasculature morphogenesis in camera-type eye	4/232	10/18986	0.4	32.7344827586207	11.1642981381418	4.30673973166255e-06	5.27668168842094e-05	2.63561300423566e-05	CYP1B1/LAMA1/COL4A1/NRP1	4
BP	GO:0070989	oxidative demethylation	4/232	10/18986	0.4	32.7344827586207	11.1642981381418	4.30673973166255e-06	5.27668168842094e-05	2.63561300423566e-05	CYP3A4/CYP1A2/CYP2C9/CYP2D6	4
BP	GO:1904018	positive regulation of vasculature development	12/232	192/18986	0.0625	5.11476293103448	6.37364923737784	4.44532191257821e-06	5.40179341636096e-05	2.69810419029009e-05	VEGFA/KDR/NTRK1/PRKCA/ITGB1/CXCL8/ERAP1/CYP1B1/TGFBR1/NRP1/FLT1/GRN	12
BP	GO:1901099	negative regulation of signal transduction in absence of ligand	6/232	36/18986	0.166666666666667	13.639367816092	8.44256344385092	4.47288331753296e-06	5.40179341636096e-05	2.69810419029009e-05	HSPA1A/COL2A1/PF4/TNF/BCL2L1/BCL2	6
BP	GO:2000352	negative regulation of endothelial cell apoptotic process	6/232	36/18986	0.166666666666667	13.639367816092	8.44256344385092	4.47288331753296e-06	5.40179341636096e-05	2.69810419029009e-05	KDR/ICAM1/FGA/FGB/FGG/BRAF	6
BP	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	6/232	36/18986	0.166666666666667	13.639367816092	8.44256344385092	4.47288331753296e-06	5.40179341636096e-05	2.69810419029009e-05	HSPA1A/COL2A1/PF4/TNF/BCL2L1/BCL2	6
BP	GO:0015844	monoamine transport	8/232	77/18986	0.103896103896104	8.50246305418719	7.33697914192232	4.48850417429193e-06	5.40179341636096e-05	2.69810419029009e-05	SNCA/KCNA2/MAOB/HTR1A/HTR2A/SLC6A4/SLC6A3/ADORA3	8
BP	GO:0008277	regulation of G protein-coupled receptor signaling pathway	11/232	160/18986	0.06875	5.62623922413793	6.53599013464016	4.49728357395814e-06	5.40179341636096e-05	2.69810419029009e-05	SNCA/PDE4A/PDE3A/PDE6H/PDE4D/PDE4B/PDE3B/PRKCA/CXCL8/F2/PPP3CA	11
BP	GO:0072006	nephron development	11/232	160/18986	0.06875	5.62623922413793	6.53599013464016	4.49728357395814e-06	5.40179341636096e-05	2.69810419029009e-05	VEGFA/PDGFRB/PDGFRA/EGR1/EDNRA/COL4A3/COL4A4/LAMA5/LAMB2/PPP3CA/BCL2	11
BP	GO:0003012	muscle system process	19/232	465/18986	0.0408602150537634	3.34384501297738	5.69148359575878	4.76042189847238e-06	5.70183866606944e-05	2.84797170337622e-05	TPM3/PDE5A/PDE4D/PDE4B/PRKCA/NR4A3/RHOA/EDNRA/CHUK/ALDOA/LMNA/FLNA/MYH7/NR4A1/COL6A1/HTR2A/TNF/PPP3CA/PTGS2	19
BP	GO:0042742	defense response to bacterium	16/232	342/18986	0.0467836257309941	3.82859447469248	5.87106017870304	5.10301323608569e-06	6.09510742946994e-05	3.04440278036397e-05	SHC1/PRKCD/PLA2G2A/XIAP/LTF/F2/FGA/FGB/IL12B/ADAMTS5/KLRK1/MICA/HLA-A/GRN/TNF/HAVCR2	16
BP	GO:1904645	response to amyloid-beta	7/232	56/18986	0.125	10.229525862069	7.69308329977366	5.17940324813124e-06	6.16911651504434e-05	3.08136906332159e-05	MMP2/ICAM1/MMP9/MMP13/MMP3/EPHB2/TNF	7
BP	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	6/232	37/18986	0.162162162162162	13.2707362534949	8.30961060733251	5.28440264038318e-06	6.2593090554788e-05	3.12641870749015e-05	IKBKB/ERAP1/LNPEP/ERAP2/MICA/HLA-A	6
BP	GO:0007431	salivary gland development	6/232	37/18986	0.162162162162162	13.2707362534949	8.30961060733251	5.28440264038318e-06	6.2593090554788e-05	3.12641870749015e-05	LAMA1/LAMA5/PDGFA/NRP1/TNF/HGF	6
BP	GO:0036294	cellular response to decreased oxygen levels	11/232	163/18986	0.0674846625766871	5.52268880896975	6.44983233011171	5.37848453470265e-06	6.34987097119702e-05	3.17165284834788e-05	VEGFA/CCNA2/INHBA/RORA/CDKN1B/MAP1LC3A/TP53/LMNA/MDM2/BCL2/PTGS2	11
BP	GO:0030098	lymphocyte differentiation	18/232	426/18986	0.0422535211267606	3.4578678970374	5.70659022471984	5.39055931371497e-06	6.34987097119702e-05	3.17165284834788e-05	NTRK1/RHOA/ITGB1/EGR1/INHBA/RORA/ATM/SMARCA4/MMP14/TP53/CDKN2A/IL18R1/BRD4/IL12B/BRAF/LIPA/PRKCZ/BCL2	18
BP	GO:0002449	lymphocyte mediated immunity	17/232	386/18986	0.0440414507772021	3.60418527782741	5.74925268831194	5.75044437560449e-06	6.74416554413142e-05	3.36859629979879e-05	ICAM1/IL1R1/MASP2/PRKCD/FCGR2A/IL18R1/IL12B/HSPA8/KLRK1/MICA/HLA-A/TNFSF13/FCGR3A/TNF/HAVCR2/PRKCZ/AHR	17
BP	GO:1901888	regulation of cell junction assembly	14/232	268/18986	0.0522388059701493	4.27502573340196	6.00557686275081	5.78010788029407e-06	6.74416554413142e-05	3.36859629979879e-05	VEGFA/KDR/NTRK1/NTRK2/SNCA/RHOA/PRKCH/IKBKB/MMP14/EPHB2/EPHB3/EPHB1/NRP1/TNF	14
BP	GO:0010563	negative regulation of phosphorus metabolic process	15/232	306/18986	0.0490196078431373	4.01157876943881	5.9070254433331	5.78837407552907e-06	6.74416554413142e-05	3.36859629979879e-05	SNCA/PDE4D/INHBA/PRKCD/PRKCH/CDKN1B/TP53/CDKN2A/EPHB2/NTRK3/PPIA/PDGFA/TNF/PRKCZ/MAPT	15
BP	GO:0045936	negative regulation of phosphate metabolic process	15/232	306/18986	0.0490196078431373	4.01157876943881	5.9070254433331	5.78837407552907e-06	6.74416554413142e-05	3.36859629979879e-05	SNCA/PDE4D/INHBA/PRKCD/PRKCH/CDKN1B/TP53/CDKN2A/EPHB2/NTRK3/PPIA/PDGFA/TNF/PRKCZ/MAPT	15
BP	GO:0002706	regulation of lymphocyte mediated immunity	12/232	198/18986	0.0606060606060606	4.95977011494253	6.22966409960359	6.09638704799779e-06	7.08373668946699e-05	3.53820632734196e-05	IL1R1/IL18R1/IL12B/HSPA8/KLRK1/MICA/HLA-A/TNFSF13/TNF/HAVCR2/PRKCZ/AHR	12
BP	GO:0010742	macrophage derived foam cell differentiation	6/232	38/18986	0.157894736842105	12.9215063520871	8.18170058504812	6.21153075800118e-06	7.17851500573326e-05	3.58554648875801e-05	PRKCH/PLA2G2A/PLA2G5/PLA2G10/ABCA1/PF4	6
BP	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	6/232	38/18986	0.157894736842105	12.9215063520871	8.18170058504812	6.21153075800118e-06	7.17851500573326e-05	3.58554648875801e-05	ATM/ATR/TP53/CDKN2A/MDM2/DYRK1A	6
BP	GO:0009261	ribonucleotide catabolic process	10/232	135/18986	0.0740740740740741	6.06194125159642	6.56476411061684	6.34938973942306e-06	7.31805674549137e-05	3.6552452209645e-05	PDE5A/PDE4A/PDE4D/PDE4B/PDE8B/ALDOA/COL6A1/HTR2A/INS/LIPA	10
BP	GO:0061900	glial cell activation	7/232	58/18986	0.120689655172414	9.87678359096314	7.53042699845669	6.57722808114195e-06	7.54250917390079e-05	3.76735540196069e-05	SNCA/ITGB2/ATM/MMP8/GRN/TNF/MAPT	7
BP	GO:0006809	nitric oxide biosynthetic process	8/232	81/18986	0.0987654320987654	8.0825883354619	7.10474517523154	6.57941048144293e-06	7.54250917390079e-05	3.76735540196069e-05	ESR1/RORA/CYP1B1/GLA/KLRK1/CLEC7A/TNF/PTGS2	8
BP	GO:0071492	cellular response to UV-A	4/232	11/18986	0.363636363636364	29.7586206896552	10.6114770804826	6.70284356506e-06	7.66346499577448e-05	3.82777078342435e-05	MMP2/MMP1/MMP9/MMP3	4
BP	GO:0002708	positive regulation of lymphocyte mediated immunity	10/232	136/18986	0.0735294117647059	6.01736815415821	6.53118646813713	6.78089190858944e-06	7.73202501363425e-05	3.86201534948153e-05	IL1R1/IL18R1/IL12B/HSPA8/KLRK1/MICA/HLA-A/TNFSF13/TNF/PRKCZ	10
BP	GO:0050708	regulation of protein secretion	14/232	272/18986	0.0514705882352941	4.21215770791075	5.93472140471578	6.84808022618431e-06	7.78786995935216e-05	3.8899089526674e-05	HMGCR/PDE8B/PRKCA/F2/FGA/FGB/FGG/IL12B/PPIA/INS/TNF/PPP3CA/HNF4A/ALOX5	14
BP	GO:0008637	apoptotic mitochondrial changes	9/232	108/18986	0.0833333333333333	6.81968390804598	6.74583355187451	7.12497494480325e-06	8.05989229205785e-05	4.02577949401442e-05	MMP9/HSPA1A/PLAUR/TP53/CDKN2A/LMNA/HGF/BCL2L1/BCL2	9
BP	GO:1990266	neutrophil migration	9/232	108/18986	0.0833333333333333	6.81968390804598	6.74583355187451	7.12497494480325e-06	8.05989229205785e-05	4.02577949401442e-05	ITGA1/PDE4B/ITGB2/IL1R1/CXCL8/PPIA/CXCR1/PF4/CXCR2	9
BP	GO:0014823	response to activity	8/232	82/18986	0.0975609756097561	7.98402018502944	7.04916855275634	7.21473554809425e-06	8.13989688750686e-05	4.06574043246306e-05	MMP2/ITGB1/CDK1/COL6A1/COL4A2/HSPA8/TNF/SRD5A1	8
BP	GO:0032768	regulation of monooxygenase activity	6/232	39/18986	0.153846153846154	12.5901856763926	8.05851106887242	7.26639913698687e-06	8.15515031752122e-05	4.07335926203795e-05	SNCA/ESR1/GLA/INS/TNF/NPR3	6
BP	GO:0090077	foam cell differentiation	6/232	39/18986	0.153846153846154	12.5901856763926	8.05851106887242	7.26639913698687e-06	8.15515031752122e-05	4.07335926203795e-05	PRKCH/PLA2G2A/PLA2G5/PLA2G10/ABCA1/PF4	6
BP	GO:0031290	retinal ganglion cell axon guidance	5/232	23/18986	0.217391304347826	17.7904797601199	8.9613994948392	7.33664220306018e-06	8.21242985871344e-05	4.1019694213307e-05	VEGFA/EPHB2/EPHB3/EPHB1/NRP1	5
BP	GO:0043269	regulation of monoatomic ion transport	19/232	480/18986	0.0395833333333333	3.23934985632184	5.52698933232875	7.48860425623369e-06	8.36064537850007e-05	4.17600055954326e-05	SNCA/CRBN/PDE4D/PDE4B/PDGFRB/ITGB1/MMP9/EDNRA/MAOB/EPHB2/FLNA/F2/HTR1A/HTR2A/PPP3CA/CA2/BCL2/PTGS2/SLC6A4	19
BP	GO:0010951	negative regulation of endopeptidase activity	9/232	109/18986	0.0825688073394495	6.75711800063271	6.70431219315277	7.68465933851146e-06	8.55257722850293e-05	4.27186726321511e-05	VEGFA/SNCA/MMP9/XIAP/PLAUR/LTF/RAF1/TNF/PTGS2	9
BP	GO:0006195	purine nucleotide catabolic process	10/232	138/18986	0.072463768115942	5.93015992003998	6.46502562715514	7.72052107156719e-06	8.55257722850293e-05	4.27186726321511e-05	PDE5A/PDE4A/PDE4D/PDE4B/PDE8B/ALDOA/COL6A1/HTR2A/INS/LIPA	10
BP	GO:0035270	endocrine system development	10/232	138/18986	0.072463768115942	5.93015992003998	6.46502562715514	7.72052107156719e-06	8.55257722850293e-05	4.27186726321511e-05	APOA1/PDGFRA/EDNRA/THRA/CYP1B1/RAF1/BRAF/TGFBR1/SRD5A1/SLC6A3	10
BP	GO:0007162	negative regulation of cell adhesion	15/232	314/18986	0.0477707006369427	3.90937294091808	5.78190747148615	7.89167919837037e-06	8.71959179644231e-05	4.35528820712457e-05	VEGFA/MMP2/PDE5A/PDE3B/RHOA/APOA1/PRKCD/PLA2G5/MMP14/CYP1B1/CDKN2A/EPHB2/COL1A1/PLG/HAVCR2	15
BP	GO:0043524	negative regulation of neuron apoptotic process	11/232	170/18986	0.0647058823529412	5.29528397565923	6.25683968719357	8.04253639202995e-06	8.86337258049486e-05	4.42710427005664e-05	KDR/NTRK1/NTRK2/NR4A2/SNCA/RHOA/BRAF/NRP1/GRN/BCL2L1/BCL2	11
BP	GO:0006909	phagocytosis	13/232	239/18986	0.0543933054393305	4.45134179772039	5.9720490928655	8.11497498987401e-06	8.92021415339364e-05	4.45549567161531e-05	APOA1/MYH9/ITGB1/ITGAL/ITGB2/PRKCD/FCGR2A/PLA2G5/AHSG/ABCA1/HSPA8/CLEC7A/ALOX15	13
BP	GO:0042063	gliogenesis	16/232	355/18986	0.0450704225352113	3.68839242350656	5.68710299803226	8.16443659902976e-06	8.9515720249875e-05	4.47115839660766e-05	NTRK2/RHOA/PRKCH/CDK1/MMP14/TP53/F2/COL3A1/COL6A1/LAMB1/LAMB2/RAF1/GRN/TNF/MAPT/PLEC	16
BP	GO:0002366	leukocyte activation involved in immune response	15/232	315/18986	0.0476190476190476	3.89696223316913	5.76655791667366	8.19747836314767e-06	8.96481265494103e-05	4.47777186669178e-05	NR4A3/ITGAL/ICAM1/ITGB2/RORA/TP53/IL18R1/BRD4/IL12B/TNFSF13/GRN/FCGR3A/TNF/HAVCR2/PRKCZ	15
BP	GO:0051701	biological process involved in interaction with host	12/232	204/18986	0.0588235294117647	4.81389452332657	6.09137281852957	8.26376214728614e-06	8.96502884084172e-05	4.47787984788239e-05	DDB1/ITGB1/ICAM1/ITGB7/CXCL8/HSPA1A/CDK1/LTF/ANPEP/HTR2A/PPIA/NRP1	12
BP	GO:0046456	icosanoid biosynthetic process	7/232	60/18986	0.116666666666667	9.54755747126437	7.37548483211801	8.27503730392205e-06	8.96502884084172e-05	4.47787984788239e-05	PLA2G5/PLA2G10/CYP2C9/LTA4H/ALOX5/PTGS1/PTGS2	7
BP	GO:0060350	endochondral bone morphogenesis	7/232	60/18986	0.116666666666667	9.54755747126437	7.37548483211801	8.27503730392205e-06	8.96502884084172e-05	4.47787984788239e-05	MMP13/MMP14/COL1A1/COL2A1/COL3A1/COL27A1/NPR2	7
BP	GO:0002526	acute inflammatory response	9/232	110/18986	0.0818181818181818	6.69568965517241	6.66330991665314	8.28153973838279e-06	8.96502884084172e-05	4.47787984788239e-05	FCGR2A/AHSG/F2/B4GALT1/INS/FCGR3A/LIPA/TNF/PTGS2	9
BP	GO:0090199	regulation of release of cytochrome c from mitochondria	6/232	40/18986	0.15	12.2754310344828	7.93974801727588	8.46196237375051e-06	9.13720987630232e-05	4.56388135468894e-05	MMP9/PLAUR/TP53/LMNA/HGF/BCL2L1	6
BP	GO:0055001	muscle cell development	12/232	205/18986	0.0585365853658537	4.79041211101766	6.06884914929699	8.68409678492389e-06	9.35345034063843e-05	4.6718897989157e-05	VEGFA/PDGFRB/PDGFRA/ITGB1/EDNRA/CDK1/LMNA/MYH7/COL6A1/PPP3CA/BCL2/PLEC	12
BP	GO:0042445	hormone metabolic process	13/232	241/18986	0.0539419087136929	4.41440120188868	5.93311391582796	8.8762735702517e-06	9.53641853929555e-05	4.76327931077511e-05	PDE8B/PDGFRA/EGR1/INHBA/ESR1/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2D6/CYP1B1/CYP2S1/SRD5A1	13
BP	GO:0034114	regulation of heterotypic cell-cell adhesion	5/232	24/18986	0.208333333333333	17.0492097701149	8.75023145017623	9.17539062936338e-06	9.83307527096687e-05	4.9114543165752e-05	APOA1/FGA/FGB/FGG/TNF	5
BP	GO:0043030	regulation of macrophage activation	7/232	61/18986	0.114754098360656	9.39104013566987	7.30071019323939	9.25142179426297e-06	9.88976989806712e-05	4.93977232119989e-05	SNCA/RORA/ATM/MMP8/PLA2G10/GRN/HAVCR2	7
BP	GO:0030593	neutrophil chemotaxis	8/232	85/18986	0.0941176470588235	7.70223123732252	6.88793145715991	9.44034694684316e-06	0.000100665644749879	5.02807821371434e-05	ITGA1/PDE4B/ITGB2/CXCL8/PPIA/CXCR1/PF4/CXCR2	8
BP	GO:0002263	cell activation involved in immune response	15/232	319/18986	0.0470219435736677	3.84809750297265	5.70578322929285	9.52887653006126e-06	0.000101356905578463	5.06260551963716e-05	NR4A3/ITGAL/ICAM1/ITGB2/RORA/TP53/IL18R1/BRD4/IL12B/TNFSF13/GRN/FCGR3A/TNF/HAVCR2/PRKCZ	15
BP	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	9/232	112/18986	0.0803571428571429	6.57612376847291	6.58281694182858	9.59502591209263e-06	0.000101807272456844	5.08510058133367e-05	MMP9/HSPA1A/PLAUR/MDM2/PPIA/INS/BCL2L1/BCL2/PTGS2	9
BP	GO:0045860	positive regulation of protein kinase activity	13/232	243/18986	0.0534979423868313	4.37806868170853	5.89460077416999	9.69985986426479e-06	0.000102664853414842	5.12793529562096e-05	SNCA/PDE5A/RHOA/PDGFRB/PRKCD/TPX2/LTF/NTRK3/PPIA/PDGFA/FLT1/INS/TNF	13
BP	GO:0002360	T cell lineage commitment	6/232	41/18986	0.146341463414634	11.9760302775442	7.82514254054548	9.81202156707981e-06	0.000103595565977366	5.17442280951395e-05	RHOA/TP53/BRD4/IL12B/BRAF/BCL2	6
BP	GO:0007210	serotonin receptor signaling pathway	4/232	12/18986	0.333333333333333	27.2787356321839	10.1278667340456	9.95789853351665e-06	0.000104362681689503	5.21273893821086e-05	HTR3A/HTR3B/HTR1A/HTR2A	4
BP	GO:0071872	cellular response to epinephrine stimulus	4/232	12/18986	0.333333333333333	27.2787356321839	10.1278667340456	9.95789853351665e-06	0.000104362681689503	5.21273893821086e-05	SNCA/PDE4D/PDE4B/SRD5A1	4
BP	GO:2001046	positive regulation of integrin-mediated signaling pathway	4/232	12/18986	0.333333333333333	27.2787356321839	10.1278667340456	9.95789853351665e-06	0.000104362681689503	5.21273893821086e-05	FLNA/LAMA1/LAMB1/LAMB2	4
BP	GO:0048678	response to axon injury	8/232	86/18986	0.0930232558139535	7.61267040898156	6.83592891357584	1.03001855983475e-05	0.000107383222639933	5.36360983546904e-05	NTRK1/MMP2/CDK1/FLNA/LAMB2/BRAF/GRN/BCL2	8
BP	GO:0007611	learning or memory	14/232	282/18986	0.049645390070922	4.06279041330399	5.76337560160898	1.03205742845167e-05	0.000107383222639933	5.36360983546904e-05	NTRK1/NTRK2/HMGCR/PDE8B/ITGB1/THRA/EPHB2/HTR2A/BRAF/MAN2B1/PRKCZ/MAPT/PTGS2/SLC6A4	14
BP	GO:1900024	regulation of substrate adhesion-dependent cell spreading	7/232	62/18986	0.112903225806452	9.23957174638487	7.22763732712666	1.03214463295165e-05	0.000107383222639933	5.36360983546904e-05	APOA1/FLNA/FGA/FGB/FGG/BRAF/NRP1	7
BP	GO:0044703	multi-organism reproductive process	12/232	210/18986	0.0571428571428571	4.67635467980296	5.95837523816028	1.10795338642659e-05	0.000114743326530801	5.73123454115983e-05	VEGFA/MMP2/DDR1/MMP9/ESR1/CYP1A1/LNPEP/HAVCR2/AR/BCL2/PTGS2/SLC6A4	12
BP	GO:0010821	regulation of mitochondrion organization	9/232	114/18986	0.0789473684210526	6.46075317604356	6.50426678106686	1.10825523520161e-05	0.000114743326530801	5.73123454115983e-05	KDR/MMP9/HSPA1A/PLAUR/TP53/LMNA/HGF/MAPT/BCL2L1	9
BP	GO:0050806	positive regulation of synaptic transmission	11/232	176/18986	0.0625	5.11476293103448	6.09970865821368	1.11760700337295e-05	0.000115432066338714	5.76563592637611e-05	NTRK1/NTRK2/SNCA/HMGCR/EPHB2/BRAF/INS/TNF/PRKCZ/CA2/PTGS2	11
BP	GO:0061042	vascular wound healing	5/232	25/18986	0.2	16.3672413793103	8.55140815332951	1.13554740657176e-05	0.000117002426759057	5.84407276584428e-05	VEGFA/KDR/TNF/NPR2/ALOX5	5
BP	GO:0043588	skin development	15/232	324/18986	0.0462962962962963	3.78871328224776	5.63118266245193	1.14615017807227e-05	0.000117811013496083	5.88446030189434e-05	INHBA/PRKCH/PLA2G10/COL1A2/COL1A1/COL3A1/COL5A1/COL6A1/COL5A2/LAMA5/PDGFA/TNF/PPP3CA/BCL2/PLEC	15
BP	GO:0090596	sensory organ morphogenesis	14/232	285/18986	0.0491228070175439	4.0200241984271	5.71350714822453	1.16293630057029e-05	0.000119249775089654	5.95632400317335e-05	VEGFA/KDR/NTRK2/PDE6C/KCNQ4/EDNRA/EPHB2/EPHB1/COL2A1/COL5A1/COL11A1/COL5A2/THRB/BCL2	14
BP	GO:0055002	striated muscle cell development	11/232	177/18986	0.0621468926553672	5.08586596532242	6.07421602240352	1.17902243349648e-05	0.000120610046067726	6.0242672313381e-05	VEGFA/PDGFRB/PDGFRA/ITGB1/CDK1/LMNA/MYH7/COL6A1/PPP3CA/BCL2/PLEC	11
BP	GO:0052548	regulation of endopeptidase activity	13/232	248/18986	0.0524193548387097	4.2898011679644	5.80010974360783	1.20603268644674e-05	0.0001229834245603	6.14281346149497e-05	VEGFA/SNCA/MMP9/XIAP/PLAUR/CDKN2A/LTF/COL4A3/RAF1/CLEC7A/TNF/MAPT/PTGS2	13
BP	GO:0010975	regulation of neuron projection development	18/232	452/18986	0.0398230088495575	3.2589639914556	5.40625197675527	1.20797563880557e-05	0.0001229834245603	6.14281346149497e-05	VEGFA/NTRK1/NTRK2/RHOA/DDR1/EPHB2/EPHB3/FLNA/GLA/MDM2/AP2A1/NTRK3/BRAF/NRP1/GRN/INS/PPP3CA/MAPT	18
BP	GO:0071347	cellular response to interleukin-1	8/232	88/18986	0.0909090909090909	7.43965517241379	6.73439155329266	1.22190617328014e-05	0.000124106194701802	6.1988939257042e-05	MMP2/IL1R1/EGR1/RORA/IKBKB/CXCL8/FGB/FGG	8
BP	GO:0071453	cellular response to oxygen levels	11/232	178/18986	0.0617977528089888	5.05729368461836	6.04891491109807	1.24335061142604e-05	0.000125985005081937	6.29273731749423e-05	VEGFA/CCNA2/INHBA/RORA/CDKN1B/MAP1LC3A/TP53/LMNA/MDM2/BCL2/PTGS2	11
BP	GO:2000351	regulation of endothelial cell apoptotic process	7/232	64/18986	0.109375	8.95083512931035	7.08633294099323	1.27704514471424e-05	0.00012799423406815	6.39309489745154e-05	KDR/ICAM1/FGA/FGB/FGG/BRAF/TNF	7
BP	GO:1901990	regulation of mitotic cell cycle phase transition	16/232	368/18986	0.0434782608695652	3.55809595202399	5.5115856935728	1.27730965784309e-05	0.00012799423406815	6.39309489745154e-05	DDB1/CDC7/CDK2/INHBA/ATM/ATR/CDK1/CDKN1B/ADAMTS1/SMARCA4/CYP1A1/TP53/CDKN2A/MDM2/BRD4/BCL2	16
BP	GO:0071383	cellular response to steroid hormone stimulus	12/232	213/18986	0.0563380281690141	4.6104905293832	5.89374727295443	1.27789443831372e-05	0.00012799423406815	6.39309489745154e-05	PDE3A/NR4A3/SKP2/RHOA/ESR1/HSPA1A/ESR2/SMARCA4/CYP1B1/HSPA8/AR/SRD5A1	12
BP	GO:0097193	intrinsic apoptotic signaling pathway	15/232	327/18986	0.0458715596330275	3.75395444479595	5.58713008726999	1.27814635049345e-05	0.00012799423406815	6.39309489745154e-05	MMP2/MMP9/PRKCD/ATM/HSPA1A/PLAUR/CYP1B1/TP53/MDM2/PPIA/INS/TNF/BCL2L1/BCL2/PTGS2	15
BP	GO:1904951	positive regulation of establishment of protein localization	15/232	327/18986	0.0458715596330275	3.75395444479595	5.58713008726999	1.27814635049345e-05	0.00012799423406815	6.39309489745154e-05	PRKCA/ITGB2/PRKCD/CDK1/FLNA/MDM2/F2/FGA/FGB/FGG/PPIA/INS/TNF/PRKCZ/PTGS2	15
BP	GO:0042886	amide transport	15/232	328/18986	0.0457317073170732	3.74250946173255	5.57256123392301	1.32505095346378e-05	0.000132381258808672	6.61221934229714e-05	PDE8B/PRKCA/PSAP/ABCA1/F2/FGA/FGB/FGG/RAF1/INS/TNF/PPP3CA/HNF4A/ALOX5/CA2	15
BP	GO:0016101	diterpenoid metabolic process	8/232	89/18986	0.0898876404494382	7.35606354126308	6.68481109807306	1.32861014841333e-05	0.000132427435771921	6.61452580328954e-05	CYP3A4/CYP1A1/CYP1A2/CYP2D6/CYP1B1/CYP2S1/LIPA/SRD5A1	8
BP	GO:0009306	protein secretion	16/232	371/18986	0.0431266846361186	3.52932428664374	5.47220408585165	1.4120289496223e-05	0.000140200815778273	7.00279294998069e-05	HMGCR/PDE8B/PRKCA/ABCA1/F2/FGA/FGB/FGG/IL12B/RAF1/PPIA/INS/TNF/PPP3CA/HNF4A/ALOX5	16
BP	GO:0021545	cranial nerve development	7/232	65/18986	0.107692307692308	8.8131299734748	7.01797831240337	1.41643480861117e-05	0.000140200815778273	7.00279294998069e-05	NTRK1/KCNA2/NRP2/EPHB2/EPHB1/NRP1/NPR2	7
BP	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	7/232	65/18986	0.107692307692308	8.8131299734748	7.01797831240337	1.41643480861117e-05	0.000140200815778273	7.00279294998069e-05	INHBA/HSPA1A/COL2A1/PF4/TNF/BCL2L1/BCL2	7
BP	GO:0032946	positive regulation of mononuclear cell proliferation	10/232	148/18986	0.0675675675675676	5.5294734389562	6.15266849578961	1.43012938444291e-05	0.000141229405262768	7.05416925011464e-05	PRKCQ/EPHB2/IGF2/IL12B/HLA-A/FCGR3A/PPP3CA/HAVCR2/BCL2L1/BCL2	10
BP	GO:0048568	embryonic organ development	18/232	458/18986	0.0393013100436681	3.21627014003915	5.34002758587073	1.4420759263711e-05	0.000142081029059052	7.09670641427837e-05	VEGFA/KDR/PDGFRA/KCNQ4/EDNRA/CXCL8/MMP14/TP53/EPHB2/IGF2/COL2A1/COL11A1/COL18A1/COL27A1/TGFBR1/PDGFA/TNF/PLG	18
BP	GO:0035265	organ growth	11/232	181/18986	0.0607734806629834	4.9734711373595	5.97413481171389	1.45498421568744e-05	0.000143023276006425	7.14377005113084e-05	PSAP/ESR1/MMP13/CDK1/IGF2/COL27A1/TGFBR1/NPR2/AR/BCL2/SLC6A4	11
BP	GO:0035592	establishment of protein localization to extracellular region	16/232	374/18986	0.0427807486631016	3.50101419878296	5.43322604441508	1.55925771483336e-05	0.000152745106552959	7.62935899748789e-05	HMGCR/PDE8B/PRKCA/ABCA1/F2/FGA/FGB/FGG/IL12B/RAF1/PPIA/INS/TNF/PPP3CA/HNF4A/ALOX5	16
BP	GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	7/232	66/18986	0.106060606060606	8.67959770114943	6.95107875453222	1.56817356821209e-05	0.000152745106552959	7.62935899748789e-05	SNCA/PDE3A/PDE4D/PDE4B/PDE3B/CXCL8/PPP3CA	7
BP	GO:0051341	regulation of oxidoreductase activity	7/232	66/18986	0.106060606060606	8.67959770114943	6.95107875453222	1.56817356821209e-05	0.000152745106552959	7.62935899748789e-05	SNCA/ESR1/GLA/GZMA/INS/TNF/NPR3	7
BP	GO:0090303	positive regulation of wound healing	7/232	66/18986	0.106060606060606	8.67959770114943	6.95107875453222	1.56817356821209e-05	0.000152745106552959	7.62935899748789e-05	ITGB1/CPB2/PLAU/F2/PLAT/CLEC7A/PLG	7
BP	GO:0050866	negative regulation of cell activation	12/232	219/18986	0.0547945205479452	4.484175720359	5.76802345595338	1.68735600873e-05	0.000163629109892092	8.1729965036447e-05	PDE5A/PDGFRA/INHBA/PRKCD/ATM/PLA2G5/CDKN2A/F2/PDGFA/MICA/GRN/HAVCR2	12
BP	GO:0030194	positive regulation of blood coagulation	5/232	27/18986	0.185185185185185	15.1548531289911	8.18619100458712	1.69139538288832e-05	0.000163629109892092	8.1729965036447e-05	CPB2/PLAU/F2/PLAT/PLG	5
BP	GO:1900048	positive regulation of hemostasis	5/232	27/18986	0.185185185185185	15.1548531289911	8.18619100458712	1.69139538288832e-05	0.000163629109892092	8.1729965036447e-05	CPB2/PLAU/F2/PLAT/PLG	5
BP	GO:0001909	leukocyte mediated cytotoxicity	10/232	151/18986	0.0662251655629139	5.41961635076501	6.06446606683325	1.7038834310731e-05	0.000164465136597485	8.21475461957306e-05	ICAM1/FCGR2A/F2/IL12B/HSPA8/KLRK1/MICA/HLA-A/FCGR3A/HAVCR2	10
BP	GO:0038034	signal transduction in absence of ligand	7/232	67/18986	0.104477611940299	8.55005146680391	6.88558053449406	1.73310124906901e-05	0.000166533504292563	8.31806607773155e-05	INHBA/HSPA1A/COL2A1/PF4/TNF/BCL2L1/BCL2	7
BP	GO:0070301	cellular response to hydrogen peroxide	7/232	67/18986	0.104477611940299	8.55005146680391	6.88558053449406	1.73310124906901e-05	0.000166533504292563	8.31806607773155e-05	PRKCD/CDK1/CYP1B1/MAP1LC3A/MDM2/HSPA8/TRPA1	7
BP	GO:0002790	peptide secretion	13/232	257/18986	0.0505836575875486	4.13957466791896	5.63614841130948	1.760445531527e-05	0.000168781728538328	8.43036106553758e-05	PDE8B/PRKCA/ABCA1/F2/FGA/FGB/FGG/RAF1/INS/TNF/PPP3CA/HNF4A/ALOX5	13
BP	GO:1904375	regulation of protein localization to cell periphery	10/232	153/18986	0.065359477124183	5.34877169258508	6.00696231888768	1.91044000798063e-05	0.000182752605685127	9.12818268266266e-05	SNCA/ITGB1/PRKCH/MMP14/EPHB2/INS/TNF/PRKCZ/AR/BCL2L1	10
BP	GO:0034116	positive regulation of heterotypic cell-cell adhesion	4/232	14/18986	0.285714285714286	23.3817733990148	9.31760491757456	1.97531301782577e-05	0.000187698632538289	9.37522833489704e-05	FGA/FGB/FGG/TNF	4
BP	GO:0061430	bone trabecula morphogenesis	4/232	14/18986	0.285714285714286	23.3817733990148	9.31760491757456	1.97531301782577e-05	0.000187698632538289	9.37522833489704e-05	VEGFA/MMP2/RHOA/COL1A1	4
BP	GO:0070141	response to UV-A	4/232	14/18986	0.285714285714286	23.3817733990148	9.31760491757456	1.97531301782577e-05	0.000187698632538289	9.37522833489704e-05	MMP2/MMP1/MMP9/MMP3	4
BP	GO:0021954	central nervous system neuron development	8/232	94/18986	0.0851063829787234	6.96478356566398	6.44795481543926	1.9873415556468e-05	0.000188422893391257	9.41140393606571e-05	NTRK2/NR4A2/NRP2/EPHB2/EPHB3/EPHB1/NRP1/MAPT	8
BP	GO:0071692	protein localization to extracellular region	16/232	382/18986	0.0418848167539267	3.4276945296985	5.33119898999385	2.0208216565409e-05	0.000191173305384268	9.54878235007333e-05	HMGCR/PDE8B/PRKCA/ABCA1/F2/FGA/FGB/FGG/IL12B/RAF1/PPIA/INS/TNF/PPP3CA/HNF4A/ALOX5	16
BP	GO:0045088	regulation of innate immune response	18/232	470/18986	0.0382978723404255	3.13415260454879	5.21078496149312	2.03565762213303e-05	0.000192151699607965	9.59765148206789e-05	ESR1/IKBKB/CHUK/HSPA1A/XIAP/PLA2G5/ERAP1/LTF/IL12B/HSPA8/KLRK1/MICA/HLA-A/GRN/INS/CLEC7A/TNF/HAVCR2	18
BP	GO:0046883	regulation of hormone secretion	13/232	261/18986	0.0498084291187739	4.07613291055622	5.56566130331237	2.0714224780694e-05	0.000195096971723012	9.74476282866406e-05	PDE8B/PRKCA/INHBA/F2/FGA/FGB/FGG/HTR1A/INS/TNF/PPP3CA/HNF4A/ALOX5	13
BP	GO:0045859	regulation of protein kinase activity	17/232	427/18986	0.0398126463700234	3.25811596543649	5.24910463843688	2.12786463927871e-05	0.00019997250983639	9.988287687904e-05	SNCA/PDE5A/RHOA/PDGFRB/PRKCD/PRKCH/CDKN1B/CDKN2A/TPX2/EPHB2/LTF/NTRK3/PPIA/PDGFA/FLT1/INS/TNF	17
BP	GO:0072523	purine-containing compound catabolic process	10/232	155/18986	0.0645161290322581	5.2797552836485	5.95045851173638	2.138156337193e-05	0.000200499046005204	0.000100145872764649	PDE5A/PDE4A/PDE4D/PDE4B/PDE8B/ALDOA/COL6A1/HTR2A/INS/LIPA	10
BP	GO:0071900	regulation of protein serine/threonine kinase activity	13/232	262/18986	0.049618320610687	4.06057515135562	5.54825885161823	2.15631223261385e-05	0.000201759105178487	0.000100775250949522	SNCA/PDE5A/RHOA/PDGFRB/PRKCD/PRKCH/CDKN1B/CDKN2A/LTF/NTRK3/PDGFA/FLT1/TNF	13
BP	GO:0045766	positive regulation of angiogenesis	11/232	189/18986	0.0582010582010582	4.76295384054005	5.78252953503593	2.17890928759672e-05	0.000202985100517725	0.000101387614827055	VEGFA/KDR/NTRK1/PRKCA/ITGB1/CXCL8/ERAP1/CYP1B1/NRP1/FLT1/GRN	11
BP	GO:2001242	regulation of intrinsic apoptotic signaling pathway	11/232	189/18986	0.0582010582010582	4.76295384054005	5.78252953503593	2.17890928759672e-05	0.000202985100517725	0.000101387614827055	MMP2/MMP9/HSPA1A/PLAUR/TP53/MDM2/PPIA/INS/BCL2L1/BCL2/PTGS2	11
BP	GO:0071456	cellular response to hypoxia	10/232	156/18986	0.0641025641025641	5.24591069849691	5.92257176971308	2.26049593462842e-05	0.000210127839488502	0.000104955291793159	VEGFA/CCNA2/INHBA/RORA/CDKN1B/TP53/LMNA/MDM2/BCL2/PTGS2	10
BP	GO:0043525	positive regulation of neuron apoptotic process	7/232	70/18986	0.1	8.18362068965517	6.69699689040281	2.31601045288446e-05	0.000214110534981438	0.000106944580640377	MMP2/ITGA1/ATM/TP53/HTR2A/GRN/TNF	7
BP	GO:0002042	cell migration involved in sprouting angiogenesis	8/232	96/18986	0.0833333333333333	6.81968390804598	6.35801241788536	2.31836243443419e-05	0.000214110534981438	0.000106944580640377	VEGFA/KDR/RHOA/ITGB1/EPHB4/NR4A1/NRP1/PTGS2	8
BP	GO:0007044	cell-substrate junction assembly	8/232	96/18986	0.0833333333333333	6.81968390804598	6.35801241788536	2.31836243443419e-05	0.000214110534981438	0.000106944580640377	VEGFA/KDR/RHOA/MMP14/LAMA3/NRP1/BCL2/PLEC	8
BP	GO:0006694	steroid biosynthetic process	11/232	191/18986	0.0575916230366492	4.71307997833544	5.7363040100395	2.40238530237151e-05	0.000220916119418077	0.000110343854635242	HMGCR/PDE8B/APOA1/EGR1/INHBA/CYP3A4/CYP1A1/CYP2R1/LIPA/TNF/SRD5A1	11
BP	GO:2000045	regulation of G1/S transition of mitotic cell cycle	11/232	191/18986	0.0575916230366492	4.71307997833544	5.7363040100395	2.40238530237151e-05	0.000220916119418077	0.000110343854635242	CDK2/INHBA/ATM/CDKN1B/ADAMTS1/SMARCA4/CYP1A1/TP53/CDKN2A/MDM2/BCL2	11
BP	GO:0052547	regulation of peptidase activity	15/232	346/18986	0.0433526011560694	3.54781243771178	5.3196723760755	2.47475154430837e-05	0.000227082352005635	0.000113423783225699	VEGFA/SNCA/MMP9/XIAP/PLAUR/CDKN2A/LTF/COL4A3/COL6A3/RAF1/GRN/CLEC7A/TNF/MAPT/PTGS2	15
BP	GO:0002718	regulation of cytokine production involved in immune response	9/232	126/18986	0.0714285714285714	5.84544334975369	6.06946324938572	2.48071080569354e-05	0.000227141743150868	0.000113453448095395	NR4A3/APOA1/IL1R1/IL18R1/HTR2A/HLA-A/CLEC7A/TNF/PRKCZ	9
BP	GO:0061383	trabecula morphogenesis	6/232	48/18986	0.125	10.229525862069	7.12090662529323	2.49354518052869e-05	0.00022734326635268	0.000113554105516613	VEGFA/MMP2/RHOA/ADAMTS1/COL1A1/TGFBR1	6
BP	GO:0071526	semaphorin-plexin signaling pathway	6/232	48/18986	0.125	10.229525862069	7.12090662529323	2.49354518052869e-05	0.00022734326635268	0.000113554105516613	KDR/RHOA/EDNRA/NRP2/FLNA/NRP1	6
BP	GO:0043627	response to estrogen	7/232	71/18986	0.0985915492957746	8.06835842642059	6.63661925501269	2.54289083085231e-05	0.000231348961547329	0.000115554882324733	MMP2/ESR1/ESR2/MMP14/MDM2/AR/SRD5A1	7
BP	GO:0002367	cytokine production involved in immune response	9/232	127/18986	0.0708661417322835	5.79941623676351	6.03577836468887	2.64191969507192e-05	0.000237658287531873	0.000118706283639942	NR4A3/APOA1/IL1R1/IL18R1/HTR2A/HLA-A/CLEC7A/TNF/PRKCZ	9
BP	GO:0009150	purine ribonucleotide metabolic process	15/232	348/18986	0.0431034482758621	3.52742271105826	5.2926136105715	2.64548963283843e-05	0.000237658287531873	0.000118706283639942	PDE5A/PDE4A/PDE4D/PDE4B/PDE8B/RORA/HSPA1A/ALDOA/MYH7/COL6A1/HTR2A/HSPA8/INS/LIPA/NPR2	15
BP	GO:0016125	sterol metabolic process	10/232	159/18986	0.0628930817610063	5.14693125135545	5.84032713260557	2.66423021476654e-05	0.000237658287531873	0.000118706283639942	HMGCR/APOA1/CYP3A4/CYP1A2/CYP2C9/CYP2D6/CYP1B1/ABCA1/PON1/LIPA	10
BP	GO:0045807	positive regulation of endocytosis	10/232	159/18986	0.0628930817610063	5.14693125135545	5.84032713260557	2.66423021476654e-05	0.000237658287531873	0.000118706283639942	VEGFA/SNCA/APOA1/FCGR2A/PLA2G5/AHSG/AP2A1/HSPA8/CLEC7A/PPP3CA	10
BP	GO:1902652	secondary alcohol metabolic process	10/232	159/18986	0.0628930817610063	5.14693125135545	5.84032713260557	2.66423021476654e-05	0.000237658287531873	0.000118706283639942	HMGCR/APOA1/CYP3A4/CYP1A2/CYP2C9/CYP2D6/CYP2R1/ABCA1/PON1/LIPA	10
BP	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	4/232	15/18986	0.266666666666667	21.8229885057471	8.97317038329891	2.66781987874881e-05	0.000237658287531873	0.000118706283639942	NTRK1/HTR2A/TNF/TRPA1	4
BP	GO:0061684	chaperone-mediated autophagy	4/232	15/18986	0.266666666666667	21.8229885057471	8.97317038329891	2.66781987874881e-05	0.000237658287531873	0.000118706283639942	SNCA/CTSA/EEF1A1/HSPA8	4
BP	GO:0070988	demethylation	4/232	15/18986	0.266666666666667	21.8229885057471	8.97317038329891	2.66781987874881e-05	0.000237658287531873	0.000118706283639942	CYP3A4/CYP1A2/CYP2C9/CYP2D6	4
BP	GO:0071871	response to epinephrine	4/232	15/18986	0.266666666666667	21.8229885057471	8.97317038329891	2.66781987874881e-05	0.000237658287531873	0.000118706283639942	SNCA/PDE4D/PDE4B/SRD5A1	4
BP	GO:0106072	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	4/232	15/18986	0.266666666666667	21.8229885057471	8.97317038329891	2.66781987874881e-05	0.000237658287531873	0.000118706283639942	PDE3A/PDE4D/PDE4B/PDE3B	4
BP	GO:0014037	Schwann cell differentiation	6/232	49/18986	0.122448979591837	10.0207600281492	7.03214662624655	2.81269825605929e-05	0.000249524849437957	0.000124633430040277	NTRK2/CDK1/COL6A1/LAMB2/RAF1/PLEC	6
BP	GO:0061028	establishment of endothelial barrier	6/232	49/18986	0.122448979591837	10.0207600281492	7.03214662624655	2.81269825605929e-05	0.000249524849437957	0.000124633430040277	VEGFA/PDE4D/ICAM1/EDNRA/IKBKB/TNF	6
BP	GO:0010955	negative regulation of protein processing	5/232	30/18986	0.166666666666667	13.639367816092	7.70575092435871	2.8978029471038e-05	0.000255749043930571	0.000127742309619203	CPB2/PLAU/XIAP/MDM2/PLAT	5
BP	GO:0062149	detection of stimulus involved in sensory perception of pain	5/232	30/18986	0.166666666666667	13.639367816092	7.70575092435871	2.8978029471038e-05	0.000255749043930571	0.000127742309619203	NTRK1/EPHB1/HTR2A/TNF/TRPA1	5
BP	GO:0006576	biogenic amine metabolic process	8/232	99/18986	0.0808080808080808	6.61302681992337	6.22781297318071	2.90080183129857e-05	0.000255749043930571	0.000127742309619203	NR4A2/SNCA/ITGB2/MAOA/EDNRA/MAOB/HTR1A/SLC6A3	8
BP	GO:0016042	lipid catabolic process	15/232	351/18986	0.0427350427350427	3.49727379899794	5.25239473928724	2.92111610706033e-05	0.000257010133205555	0.000128372202322404	HEXA/PDE3B/PRKCD/PLA2G2A/THRA/PLA2G5/PLA2G10/CYP3A4/CYP1A2/CYP1B1/GLA/INS/LIPA/TNF/SRD5A1	15
BP	GO:0015833	peptide transport	13/232	270/18986	0.0481481481481481	3.94026181353768	5.41207373349983	2.95265504679915e-05	0.000259251601234356	0.000129491777584685	PDE8B/PRKCA/ABCA1/F2/FGA/FGB/FGG/RAF1/INS/TNF/PPP3CA/HNF4A/ALOX5	13
BP	GO:0009166	nucleotide catabolic process	10/232	161/18986	0.062111801242236	5.08299421717713	5.78664110579957	2.9664517869645e-05	0.000259929259038119	0.00012983025616374	PDE5A/PDE4A/PDE4D/PDE4B/PDE8B/ALDOA/COL6A1/HTR2A/INS/LIPA	10
BP	GO:0003206	cardiac chamber morphogenesis	9/232	129/18986	0.0697674418604651	5.70950280673617	5.9694724475034	2.99113353968427e-05	0.000261022183993672	0.000130376153641662	EDNRA/NRP2/ADAMTS1/TP53/MYH7/MDM2/COL11A1/TGFBR1/NRP1	9
BP	GO:0051702	biological process involved in interaction with symbiont	9/232	129/18986	0.0697674418604651	5.70950280673617	5.9694724475034	2.99113353968427e-05	0.000261022183993672	0.000130376153641662	DDB1/EEF1A1/SMARCA4/BRD4/LTF/F2/HSPA8/PF4/PLG	9
BP	GO:0002040	sprouting angiogenesis	11/232	196/18986	0.0561224489795918	4.59284834623505	5.62348924703093	3.04973822345257e-05	0.000264153350600108	0.00013194011825307	VEGFA/KDR/RHOA/ITGB1/EPHB4/NR4A1/IL12B/NRP1/FLT1/ALOX5/PTGS2	11
BP	GO:0002700	regulation of production of molecular mediator of immune response	11/232	196/18986	0.0561224489795918	4.59284834623505	5.62348924703093	3.04973822345257e-05	0.000264153350600108	0.00013194011825307	NR4A3/APOA1/IL1R1/EPHB2/IL18R1/HTR2A/HLA-A/TNFSF13/CLEC7A/TNF/PRKCZ	11
BP	GO:0046631	alpha-beta T cell activation	11/232	196/18986	0.0561224489795918	4.59284834623505	5.62348924703093	3.04973822345257e-05	0.000264153350600108	0.00013194011825307	RHOA/PRKCQ/RORA/IL18R1/BRD4/IL12B/BRAF/HLA-A/INS/PRKCZ/BCL2	11
BP	GO:0051881	regulation of mitochondrial membrane potential	7/232	73/18986	0.0958904109589041	7.84730751062825	6.51933635665289	3.05172486427627e-05	0.000264153350600108	0.00013194011825307	KDR/CDKN2A/COL6A1/LIPA/MAPT/BCL2L1/BCL2	7
BP	GO:0021675	nerve development	8/232	100/18986	0.08	6.54689655172414	6.18560824365627	3.12025765900252e-05	0.000268603394516072	0.000134162839710775	NTRK1/KCNA2/EDNRA/NRP2/EPHB2/EPHB1/NRP1/NPR2	8
BP	GO:0060349	bone morphogenesis	8/232	100/18986	0.08	6.54689655172414	6.18560824365627	3.12025765900252e-05	0.000268603394516072	0.000134162839710775	MMP13/MMP14/LTF/COL1A1/COL2A1/COL3A1/COL27A1/NPR2	8
BP	GO:0030902	hindbrain development	10/232	162/18986	0.0617283950617284	5.05161770966369	5.7601308383406	3.12826217186632e-05	0.000268603394516072	0.000134162839710775	ITGB1/RORA/HSPA5/TP53/EPHB2/EPHB1/FLNA/HSPA8/BCL2/SLC6A4	10
BP	GO:0050729	positive regulation of inflammatory response	10/232	162/18986	0.0617283950617284	5.05161770966369	5.7601308383406	3.12826217186632e-05	0.000268603394516072	0.000134162839710775	SNCA/FABP4/PLA2G2A/MMP8/IL17RA/IL12B/HTR2A/GRN/TNF/PTGS2	10
BP	GO:0022602	ovulation cycle process	6/232	50/18986	0.12	9.82034482758621	6.94590407170886	3.16387702899587e-05	0.000270574763519727	0.000135147505091213	MMP2/PDGFRA/INHBA/ESR1/ADAMTS1/NPR2	6
BP	GO:0048538	thymus development	6/232	50/18986	0.12	9.82034482758621	6.94590407170886	3.16387702899587e-05	0.000270574763519727	0.000135147505091213	ATM/EPHB3/RAF1/BRAF/TGFBR1/BCL2	6
BP	GO:0008286	insulin receptor signaling pathway	9/232	130/18986	0.0692307692307692	5.66558355437666	5.93683802497223	3.17992402642657e-05	0.000271404294151697	0.000135561841572003	SHC1/PRKCD/PRKCQ/AHSG/IGF2/COL6A1/RAF1/INS/PRKCZ	9
BP	GO:1903053	regulation of extracellular matrix organization	7/232	74/18986	0.0945945945945946	7.74126281453868	6.46235373216239	3.33590033322691e-05	0.000284149598105145	0.000141927904720432	DDR1/CPB2/LAMA1/COL6A1/LAMB1/LAMB2/TGFBR1	7
BP	GO:0048661	positive regulation of smooth muscle cell proliferation	8/232	101/18986	0.0792079207920792	6.48207579378627	6.14397677511105	3.35343286511246e-05	0.000285075127857274	0.000142390191133477	MMP2/NR4A3/PDGFRB/MMP9/ADAMTS1/MDM2/TNF/PTGS2	8
BP	GO:0021602	cranial nerve morphogenesis	5/232	31/18986	0.161290322580645	13.1993882091212	7.56065361248474	3.42085464027346e-05	0.000289654939441769	0.000144677729340591	KCNA2/NRP2/EPHB2/EPHB1/NRP1	5
BP	GO:0050820	positive regulation of coagulation	5/232	31/18986	0.161290322580645	13.1993882091212	7.56065361248474	3.42085464027346e-05	0.000289654939441769	0.000144677729340591	CPB2/PLAU/F2/PLAT/PLG	5
BP	GO:0010976	positive regulation of neuron projection development	10/232	164/18986	0.0609756097560976	4.9900126156434	5.70775923865033	3.47465944116001e-05	0.000293629323525696	0.00014666286677998	NTRK1/NTRK2/DDR1/EPHB2/FLNA/AP2A1/NTRK3/BRAF/GRN/INS	10
BP	GO:0032354	response to follicle-stimulating hormone	4/232	16/18986	0.25	20.4590517241379	8.66064696373715	3.52304997299007e-05	0.00029695149222662	0.00014832223369795	INHBA/EDNRA/CYP1B1/SRD5A1	4
BP	GO:1902903	regulation of supramolecular fiber organization	16/232	400/18986	0.04	3.27344827586207	5.1112184693771	3.52786150727603e-05	0.00029695149222662	0.00014832223369795	SNCA/RHOA/APOA1/PRKCD/HSPA1A/CDKN1B/TPX2/FLNA/COL6A1/BRAF/HSPA8/TGFBR1/NRP1/MAPT/ALOX15/DYRK1A	16
BP	GO:0097305	response to alcohol	13/232	275/18986	0.0472727272727273	3.86862068965517	5.32958399664509	3.57170555361833e-05	0.000300051334916935	0.000149870552544548	INHBA/MAOB/CDK1/CYP1B1/MDM2/ABCA1/HSPA8/TGFBR1/LIPA/TNF/AHR/BCL2L1/SLC6A3	13
BP	GO:0048534	hematopoietic or lymphoid organ development	8/232	102/18986	0.0784313725490196	6.4185260311021	6.10290474455973	3.60100046894247e-05	0.00030191917657251	0.000150803507770573	ATM/TP53/EPHB3/RAF1/BRAF/TGFBR1/LIPA/BCL2	8
BP	GO:0002711	positive regulation of T cell mediated immunity	7/232	75/18986	0.0933333333333333	7.63804597701149	6.40642841687315	3.64147089932619e-05	0.000303526892115376	0.000151606534415366	IL1R1/IL18R1/IL12B/HSPA8/MICA/HLA-A/PRKCZ	7
BP	GO:0045123	cellular extravasation	7/232	75/18986	0.0933333333333333	7.63804597701149	6.40642841687315	3.64147089932619e-05	0.000303526892115376	0.000151606534415366	ITGA1/ITGB1/ITGAL/ICAM1/IL1R1/ITGB7/TNF	7
BP	GO:0071479	cellular response to ionizing radiation	7/232	75/18986	0.0933333333333333	7.63804597701149	6.40642841687315	3.64147089932619e-05	0.000303526892115376	0.000151606534415366	EGR1/ATM/ATR/TP53/MDM2/TNF/BCL2L1	7
BP	GO:0006633	fatty acid biosynthetic process	10/232	165/18986	0.0606060606060606	4.95977011494253	5.68189149272564	3.65982122651122e-05	0.000304462948726886	0.000152074078816122	PLA2G10/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2D6/ALOX5/PTGS1/ALOX15/PTGS2	10
BP	GO:0032868	response to insulin	13/232	276/18986	0.0471014492753623	3.85460394802599	5.31331846111866	3.70827678224451e-05	0.000307298285288324	0.000153490281337701	PDE3B/SHC1/EGR1/PRKCD/PRKCQ/AHSG/IGF2/COL1A1/COL6A1/RAF1/INS/PRKCZ/SRD5A1	13
BP	GO:0071695	anatomical structure maturation	13/232	276/18986	0.0471014492753623	3.85460394802599	5.31331846111866	3.70827678224451e-05	0.000307298285288324	0.000153490281337701	VEGFA/KDR/MMP2/NR4A2/PDE3A/RHOA/EDNRA/PLA2G10/LTF/FGG/CLEC7A/NPR2/BCL2	13
BP	GO:0060560	developmental growth involved in morphogenesis	12/232	238/18986	0.0504201680672269	4.12619530570849	5.39795736555729	3.83138497857208e-05	0.000316885922018843	0.000158279143266268	VEGFA/PLAA/DDR1/ITGB1/EDNRA/ESR1/NRP2/LAMB2/NRP1/NPR2/PRKCZ/MAPT	12
BP	GO:0070665	positive regulation of leukocyte proliferation	10/232	166/18986	0.0602409638554217	4.92989198171998	5.65623161865863	3.853355374656e-05	0.000318087791158862	0.000158879456516501	PRKCQ/EPHB2/IGF2/IL12B/HLA-A/FCGR3A/PPP3CA/HAVCR2/BCL2L1/BCL2	10
BP	GO:0150115	cell-substrate junction organization	8/232	103/18986	0.0776699029126214	6.35621024439237	6.06237879600953	3.86365689305073e-05	0.000318323639203949	0.000158997258614744	VEGFA/KDR/RHOA/MMP14/LAMA3/NRP1/BCL2/PLEC	8
BP	GO:0030330	DNA damage response, signal transduction by p53 class mediator	7/232	76/18986	0.0921052631578947	7.53754537205082	6.35152607076513	3.9696610484993e-05	0.000325801739796219	0.00016273244302263	ATM/ATR/CDKN1B/TP53/CDKN2A/MDM2/DYRK1A	7
BP	GO:1902893	regulation of miRNA transcription	7/232	76/18986	0.0921052631578947	7.53754537205082	6.35152607076513	3.9696610484993e-05	0.000325801739796219	0.00016273244302263	VEGFA/EGR1/ESR1/SMARCA4/TP53/TNF/AR	7
BP	GO:0001958	endochondral ossification	5/232	32/18986	0.15625	12.7869073275862	7.42209924675718	4.01420355710403e-05	0.000326947322098606	0.000163304641952162	MMP13/MMP14/COL1A1/COL2A1/NPR2	5
BP	GO:0036075	replacement ossification	5/232	32/18986	0.15625	12.7869073275862	7.42209924675718	4.01420355710403e-05	0.000326947322098606	0.000163304641952162	MMP13/MMP14/COL1A1/COL2A1/NPR2	5
BP	GO:0061437	renal system vasculature development	5/232	32/18986	0.15625	12.7869073275862	7.42209924675718	4.01420355710403e-05	0.000326947322098606	0.000163304641952162	PDGFRB/PDGFRA/EGR1/EDNRA/NRP1	5
BP	GO:0061440	kidney vasculature development	5/232	32/18986	0.15625	12.7869073275862	7.42209924675718	4.01420355710403e-05	0.000326947322098606	0.000163304641952162	PDGFRB/PDGFRA/EGR1/EDNRA/NRP1	5
BP	GO:0046879	hormone secretion	14/232	319/18986	0.0438871473354232	3.59155766944114	5.19183991159326	4.04853507840698e-05	0.000329062951103632	0.000164361362756454	PDE8B/PRKCA/INHBA/F2/FGA/FGB/FGG/HTR1A/RAF1/INS/TNF/PPP3CA/HNF4A/ALOX5	14
BP	GO:0048592	eye morphogenesis	10/232	167/18986	0.0598802395209581	4.9003716704522	5.63077657446449	4.05557004751202e-05	0.000329062951103632	0.000164361362756454	VEGFA/KDR/NTRK2/PDE6C/EPHB2/EPHB1/COL5A1/COL5A2/THRB/BCL2	10
BP	GO:0033135	regulation of peptidyl-serine phosphorylation	7/232	77/18986	0.0909090909090909	7.43965517241379	6.29761390891527	4.32174211160632e-05	0.000349334012650825	0.000174486414176683	SNCA/PDE4D/NTRK3/RAF1/BRAF/TNF/PTGS2	7
BP	GO:0061614	miRNA transcription	7/232	77/18986	0.0909090909090909	7.43965517241379	6.29761390891527	4.32174211160632e-05	0.000349334012650825	0.000174486414176683	VEGFA/EGR1/ESR1/SMARCA4/TP53/TNF/AR	7
BP	GO:0034504	protein localization to nucleus	14/232	321/18986	0.043613707165109	3.56918036308948	5.16339619460504	4.33271224629981e-05	0.000349559954059962	0.000174599268078298	PRKCD/CDK1/TP53/CDKN2A/LMNA/FLNA/MDM2/F2/COL1A1/HSPA8/INS/PPP3CA/POLR1A/PTGS2	14
BP	GO:0090276	regulation of peptide hormone secretion	11/232	204/18986	0.053921568627451	4.41273664638269	5.4506623393568	4.39865004464334e-05	0.000354211442389735	0.000176922607603952	PDE8B/PRKCA/F2/FGA/FGB/FGG/INS/TNF/PPP3CA/HNF4A/ALOX5	11
BP	GO:0060324	face development	6/232	53/18986	0.113207547169811	9.26447625243982	6.70109678836467	4.43346463748035e-05	0.000355675324387729	0.000177653791832678	MMP2/PDGFRA/EDNRA/COL1A1/RAF1/BRAF	6
BP	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	6/232	53/18986	0.113207547169811	9.26447625243982	6.70109678836467	4.43346463748035e-05	0.000355675324387729	0.000177653791832678	MMP2/NR4A3/MMP9/ADAMTS1/MDM2/TNF	6
BP	GO:0051047	positive regulation of secretion	14/232	322/18986	0.0434782608695652	3.55809595202399	5.14925904782252	4.48124358821591e-05	0.000357980696917287	0.000178805286309186	SNCA/PRKCA/CPB2/ITGB2/INHBA/PLA2G10/F2/FGA/FGB/FGG/PPIA/INS/PPP3CA/SLC6A4	14
BP	GO:0007605	sensory perception of sound	10/232	169/18986	0.0591715976331361	4.84237910630484	5.58046912004097	4.48731650017927e-05	0.000357980696917287	0.000178805286309186	HEXA/KCNQ4/CDKN1B/COL1A1/COL2A1/COL11A1/COL11A2/COL4A3/THRB/NPR2	10
BP	GO:1990138	neuron projection extension	10/232	169/18986	0.0591715976331361	4.84237910630484	5.58046912004097	4.48731650017927e-05	0.000357980696917287	0.000178805286309186	VEGFA/PLAA/DDR1/ITGB1/EDNRA/NRP2/LAMB2/NRP1/PRKCZ/MAPT	10
BP	GO:0002286	T cell activation involved in immune response	9/232	136/18986	0.0661764705882353	5.41563133874239	5.74789625990981	4.5380201515718e-05	0.000359324942017183	0.000179476713936503	ITGAL/ICAM1/RORA/TP53/IL18R1/BRD4/IL12B/HAVCR2/PRKCZ	9
BP	GO:0021535	cell migration in hindbrain	4/232	17/18986	0.235294117647059	19.2555780933063	8.37529609838109	4.56298979222007e-05	0.000359324942017183	0.000179476713936503	ITGB1/EPHB2/EPHB1/FLNA	4
BP	GO:0034349	glial cell apoptotic process	4/232	17/18986	0.235294117647059	19.2555780933063	8.37529609838109	4.56298979222007e-05	0.000359324942017183	0.000179476713936503	PRKCA/PRKCD/PRKCH/TP53	4
BP	GO:0038083	peptidyl-tyrosine autophosphorylation	4/232	17/18986	0.235294117647059	19.2555780933063	8.37529609838109	4.56298979222007e-05	0.000359324942017183	0.000179476713936503	KDR/NTRK1/DDR1/DYRK1A	4
BP	GO:0048532	anatomical structure arrangement	4/232	17/18986	0.235294117647059	19.2555780933063	8.37529609838109	4.56298979222007e-05	0.000359324942017183	0.000179476713936503	KCNA2/NRP2/HSPA5/NRP1	4
BP	GO:0072224	metanephric glomerulus development	4/232	17/18986	0.235294117647059	19.2555780933063	8.37529609838109	4.56298979222007e-05	0.000359324942017183	0.000179476713936503	PDGFRB/PDGFRA/EGR1/LAMB2	4
BP	GO:0090399	replicative senescence	4/232	17/18986	0.235294117647059	19.2555780933063	8.37529609838109	4.56298979222007e-05	0.000359324942017183	0.000179476713936503	ATM/ATR/TP53/CDKN2A	4
BP	GO:0031571	mitotic G1 DNA damage checkpoint signaling	5/232	33/18986	0.151515151515152	12.3994252873563	7.28959302499037	4.68419527633318e-05	0.000366172193813541	0.000182896800070817	CDK2/ATM/CDKN1B/TP53/MDM2	5
BP	GO:0044819	mitotic G1/S transition checkpoint signaling	5/232	33/18986	0.151515151515152	12.3994252873563	7.28959302499037	4.68419527633318e-05	0.000366172193813541	0.000182896800070817	CDK2/ATM/CDKN1B/TP53/MDM2	5
BP	GO:0060351	cartilage development involved in endochondral bone morphogenesis	5/232	33/18986	0.151515151515152	12.3994252873563	7.28959302499037	4.68419527633318e-05	0.000366172193813541	0.000182896800070817	MMP13/COL1A1/COL2A1/COL27A1/NPR2	5
BP	GO:0090322	regulation of superoxide metabolic process	5/232	33/18986	0.151515151515152	12.3994252873563	7.28959302499037	4.68419527633318e-05	0.000366172193813541	0.000182896800070817	SHC1/ITGB2/PRKCD/CLEC7A/MAPT	5
BP	GO:0007292	female gamete generation	10/232	170/18986	0.0588235294117647	4.81389452332657	5.55561093318806	4.7175079289903e-05	0.00036743285800296	0.000183526480450989	MMP2/DDB1/PDE5A/PDE3A/INHBA/EDNRA/ATM/ADAMTS1/NPR2/BCL2	10
BP	GO:1990845	adaptive thermogenesis	10/232	170/18986	0.0588235294117647	4.81389452332657	5.55561093318806	4.7175079289903e-05	0.00036743285800296	0.000183526480450989	VEGFA/FABP4/THRA/SMARCA4/IL18R1/LNPEP/LAMA4/ADAMTS5/LIPA/NPR3	10
BP	GO:0031103	axon regeneration	6/232	54/18986	0.111111111111111	9.09291187739464	6.62377818961935	4.93717248596528e-05	0.000383146089836435	0.000191374973235716	MMP2/FLNA/LAMB2/BRAF/GRN/BCL2	6
BP	GO:0033138	positive regulation of peptidyl-serine phosphorylation	6/232	54/18986	0.111111111111111	9.09291187739464	6.62377818961935	4.93717248596528e-05	0.000383146089836435	0.000191374973235716	SNCA/NTRK3/RAF1/BRAF/TNF/PTGS2	6
BP	GO:0009259	ribonucleotide metabolic process	15/232	368/18986	0.0407608695652174	3.33571495502249	5.03245123396578	5.01596441797597e-05	0.000387678098093895	0.000193638634491781	PDE5A/PDE4A/PDE4D/PDE4B/PDE8B/RORA/HSPA1A/ALDOA/MYH7/COL6A1/HTR2A/HSPA8/INS/LIPA/NPR2	15
BP	GO:0002791	regulation of peptide secretion	11/232	207/18986	0.0531400966183575	4.34878394136265	5.3881342437681	5.02277049448124e-05	0.000387678098093895	0.000193638634491781	PDE8B/PRKCA/F2/FGA/FGB/FGG/INS/TNF/PPP3CA/HNF4A/ALOX5	11
BP	GO:0090087	regulation of peptide transport	11/232	207/18986	0.0531400966183575	4.34878394136265	5.3881342437681	5.02277049448124e-05	0.000387678098093895	0.000193638634491781	PDE8B/PRKCA/F2/FGA/FGB/FGG/INS/TNF/PPP3CA/HNF4A/ALOX5	11
BP	GO:0001938	positive regulation of endothelial cell proliferation	8/232	107/18986	0.0747663551401869	6.1185949081534	5.90548394666867	5.07994209783005e-05	0.00039127428302753	0.000195434867870331	VEGFA/KDR/PRKCA/NRP2/IGF2/NR4A1/TGFBR1/NRP1	8
BP	GO:0002456	T cell mediated immunity	9/232	138/18986	0.0652173913043478	5.33714392803598	5.68739089566602	5.08766373627939e-05	0.00039127428302753	0.000195434867870331	ICAM1/IL1R1/IL18R1/IL12B/HSPA8/MICA/HLA-A/PRKCZ/AHR	9
BP	GO:0016485	protein processing	12/232	246/18986	0.0487804878048781	3.99201009251472	5.25349292549892	5.27908791203794e-05	0.000405267143839753	0.00020242406450959	MYH9/CPB2/PLAU/XIAP/PLAUR/MMP14/MDM2/FGA/FGB/FGG/PLAT/PLG	12
BP	GO:0002709	regulation of T cell mediated immunity	8/232	108/18986	0.0740740740740741	6.06194125159642	5.86750305895944	5.42933766609803e-05	0.000415189546254096	0.000207380136219182	IL1R1/IL18R1/IL12B/HSPA8/MICA/HLA-A/PRKCZ/AHR	8
BP	GO:0032760	positive regulation of tumor necrosis factor production	8/232	108/18986	0.0740740740740741	6.06194125159642	5.86750305895944	5.42933766609803e-05	0.000415189546254096	0.000207380136219182	FCGR2A/MMP8/EPHB2/IL12B/PF4/CLEC7A/FCGR3A/HAVCR2	8
BP	GO:0002418	immune response to tumor cell	5/232	34/18986	0.147058823529412	12.0347363083164	7.16269125569089	5.43746833260744e-05	0.000415189546254096	0.000207380136219182	IL12B/MICA/HLA-A/HAVCR2/AHR	5
BP	GO:0030308	negative regulation of cell growth	10/232	173/18986	0.0578034682080925	4.73041658361571	5.48218509174799	5.46950166923141e-05	0.000416891071972077	0.000208230019455306	INHBA/HSPA1A/ESR2/CDKN1B/SMARCA4/TP53/CDKN2A/NRP1/HNF4A/BCL2	10
BP	GO:0051216	cartilage development	11/232	209/18986	0.0526315789473684	4.30716878402904	5.34710530755594	5.47990188658554e-05	0.000416940577705334	0.000208254746729389	THRA/MMP13/COL1A1/COL2A1/COL3A1/COL6A1/COL11A1/COL27A1/COL11A2/TGFBR1/NPR2	11
BP	GO:0002534	cytokine production involved in inflammatory response	7/232	80/18986	0.0875	7.16066810344828	6.14151216656813	5.53476249392343e-05	0.000419621355035755	0.000209593749536593	PLA2G10/EPHB2/IL17RA/F2/CLEC7A/TNF/ALOX5	7
BP	GO:1900015	regulation of cytokine production involved in inflammatory response	7/232	80/18986	0.0875	7.16066810344828	6.14151216656813	5.53476249392343e-05	0.000419621355035755	0.000209593749536593	PLA2G10/EPHB2/IL17RA/F2/CLEC7A/TNF/ALOX5	7
BP	GO:0002702	positive regulation of production of molecular mediator of immune response	9/232	140/18986	0.0642857142857143	5.26089901477832	5.62805072648818	5.6924632847246e-05	0.000430813681512963	0.000215184126776082	NR4A3/IL1R1/EPHB2/IL18R1/HTR2A/HLA-A/TNFSF13/CLEC7A/PRKCZ	9
BP	GO:0048660	regulation of smooth muscle cell proliferation	10/232	174/18986	0.0574712643678161	4.70323028141102	5.45808375234004	5.74184504895402e-05	0.000433783205465148	0.000216667353623353	MMP2/NR4A3/PDGFRB/MMP9/CDKN1B/ADAMTS1/MDM2/IL12B/TNF/PTGS2	10
BP	GO:0009404	toxin metabolic process	4/232	18/18986	0.222222222222222	18.1858237547893	8.11331192257638	5.81059568524562e-05	0.000435896616668601	0.000217722966673377	CYP3A4/CYP1A1/CYP1A2/CYP1B1	4
BP	GO:0010544	negative regulation of platelet activation	4/232	18/18986	0.222222222222222	18.1858237547893	8.11331192257638	5.81059568524562e-05	0.000435896616668601	0.000217722966673377	PDGFRA/PRKCD/F2/PDGFA	4
BP	GO:0010755	regulation of plasminogen activation	4/232	18/18986	0.222222222222222	18.1858237547893	8.11331192257638	5.81059568524562e-05	0.000435896616668601	0.000217722966673377	CPB2/PLAU/PLAUR/PLAT	4
BP	GO:0071371	cellular response to gonadotropin stimulus	4/232	18/18986	0.222222222222222	18.1858237547893	8.11331192257638	5.81059568524562e-05	0.000435896616668601	0.000217722966673377	CCNA2/INHBA/EDNRA/CYP1B1	4
BP	GO:0009914	hormone transport	14/232	330/18986	0.0424242424242424	3.47183908045977	5.03814004059349	5.83908220829281e-05	0.000437266471500176	0.000218407185927295	PDE8B/PRKCA/INHBA/F2/FGA/FGB/FGG/HTR1A/RAF1/INS/TNF/PPP3CA/HNF4A/ALOX5	14
BP	GO:0031623	receptor internalization	9/232	141/18986	0.0638297872340425	5.22358767424798	5.59880493305799	6.016900987844e-05	0.000448557222357075	0.000224046724475039	VEGFA/SNCA/ITGB1/ITGB2/CXCL8/MDM2/AP2A1/CXCR1/CXCR2	9
BP	GO:0050680	negative regulation of epithelial cell proliferation	10/232	175/18986	0.0571428571428571	4.67635467980296	5.43416503408028	6.02565429922418e-05	0.000448557222357075	0.000224046724475039	CPB2/CDKN1B/IL12B/COL4A3/TGFBR1/B4GALT1/FLT1/TNF/AR/ALOX5	10
BP	GO:0051048	negative regulation of secretion	10/232	175/18986	0.0571428571428571	4.67635467980296	5.43416503408028	6.02565429922418e-05	0.000448557222357075	0.000224046724475039	SNCA/HMGCR/PDE8B/INHBA/MAOB/IL12B/BRAF/INS/TNF/PPP3CA	10
BP	GO:0060562	epithelial tube morphogenesis	14/232	331/18986	0.0422960725075529	3.46135014063965	5.02449139091205	6.03181484694382e-05	0.000448557222357075	0.000224046724475039	VEGFA/KDR/RHOA/DDR1/EDNRA/ESR1/MMP14/LAMA1/COL4A1/LAMA5/NRP1/TNF/AR/BCL2	14
BP	GO:0030072	peptide hormone secretion	12/232	250/18986	0.048	3.92813793103448	5.1835278146887	6.16561923660594e-05	0.000457711594717483	0.000228619178199442	PDE8B/PRKCA/F2/FGA/FGB/FGG/RAF1/INS/TNF/PPP3CA/HNF4A/ALOX5	12
BP	GO:0090398	cellular senescence	8/232	110/18986	0.0727272727272727	5.95172413793103	5.79295476937425	6.18834791146042e-05	0.00045780926763676	0.000228667964165966	CDK2/PRKCD/ATM/CDKN1B/NEK4/TP53/CDKN2A/LMNA	8
BP	GO:1901890	positive regulation of cell junction assembly	8/232	110/18986	0.0727272727272727	5.95172413793103	5.79295476937425	6.18834791146042e-05	0.00045780926763676	0.000228667964165966	VEGFA/KDR/NTRK1/NTRK2/EPHB2/EPHB3/EPHB1/NRP1	8
BP	GO:0071902	positive regulation of protein serine/threonine kinase activity	9/232	142/18986	0.0633802816901408	5.1868018455561	5.56983549765814	6.35678361798899e-05	0.000469457802254247	0.000234486209633664	SNCA/PDE5A/RHOA/PDGFRB/LTF/NTRK3/PDGFA/FLT1/TNF	9
BP	GO:0019693	ribose phosphate metabolic process	15/232	376/18986	0.0398936170212766	3.26474229640499	4.93334927785046	6.39399169733588e-05	0.00047139152582428	0.000235452071758521	PDE5A/PDE4A/PDE4D/PDE4B/PDE8B/RORA/HSPA1A/ALDOA/MYH7/COL6A1/HTR2A/HSPA8/INS/LIPA/NPR2	15
BP	GO:0008016	regulation of heart contraction	11/232	213/18986	0.0516431924882629	4.22628298526793	5.26656873670032	6.50227220629736e-05	0.000477706260917129	0.000238606174831583	PDE5A/PDE4D/PDE4B/EDNRA/THRA/FLNA/MYH7/MDM2/THRB/TNF/ADORA3	11
BP	GO:0032869	cellular response to insulin stimulus	11/232	213/18986	0.0516431924882629	4.22628298526793	5.26656873670032	6.50227220629736e-05	0.000477706260917129	0.000238606174831583	PDE3B/SHC1/PRKCD/PRKCQ/AHSG/IGF2/COL6A1/RAF1/INS/PRKCZ/SRD5A1	11
BP	GO:0051051	negative regulation of transport	17/232	467/18986	0.0364025695931477	2.97904821679096	4.81624295896047	6.51316066685422e-05	0.000477706260917129	0.000238606174831583	SNCA/HMGCR/CRBN/PDE8B/INHBA/MMP9/MAOB/PLA2G10/EPHB2/IL12B/HTR2A/BRAF/INS/TNF/PPP3CA/BCL2/PTGS2	17
BP	GO:0015850	organic hydroxy compound transport	13/232	292/18986	0.0445205479452055	3.64339277279169	5.06295820374803	6.60348229046051e-05	0.000483501545787828	0.000241500821329207	SNCA/APOA1/KCNA2/MAOB/PLA2G10/ABCA1/HTR1A/HTR2A/PON1/LIPA/SLC6A4/SLC6A3/ADORA3	13
BP	GO:1902905	positive regulation of supramolecular fiber organization	10/232	177/18986	0.0564971751412429	4.62351451392948	5.38686538049108	6.62924179690705e-05	0.000484557913223496	0.000242028458946008	RHOA/APOA1/HSPA1A/CDKN1B/FLNA/BRAF/TGFBR1/NRP1/MAPT/ALOX15	10
BP	GO:0051346	negative regulation of hydrolase activity	12/232	252/18986	0.0476190476190476	3.89696223316913	5.14908644808238	6.655191803775e-05	0.00048562457598877	0.000242561238905326	VEGFA/SNCA/MMP9/XIAP/PLAUR/LTF/COL6A3/GZMA/RAF1/KLRK1/TNF/PTGS2	12
BP	GO:0010212	response to ionizing radiation	9/232	143/18986	0.0629370629370629	5.15053050397878	5.54113769122003	6.7126954457936e-05	0.000488986128214879	0.000244240277226131	EGR1/ATM/ATR/CYP2R1/TP53/MDM2/TNF/BCL2L1/BCL2	9
BP	GO:0007519	skeletal muscle tissue development	10/232	178/18986	0.0561797752808989	4.59753971328942	5.36347952761787	6.94983055794761e-05	0.000504541179385127	0.000252009761452519	RHOA/EGR1/EPHB1/IGF2/NR4A1/COL6A1/HSPA8/PPP3CA/BCL2/PLEC	10
BP	GO:0048659	smooth muscle cell proliferation	10/232	178/18986	0.0561797752808989	4.59753971328942	5.36347952761787	6.94983055794761e-05	0.000504541179385127	0.000252009761452519	MMP2/NR4A3/PDGFRB/MMP9/CDKN1B/ADAMTS1/MDM2/IL12B/TNF/PTGS2	10
BP	GO:0031341	regulation of cell killing	8/232	112/18986	0.0714285714285714	5.84544334975369	5.72022212881486	7.03359703860648e-05	0.000508894432099514	0.000254184137346737	ICAM1/IL12B/HSPA8/KLRK1/MICA/HLA-A/CLEC7A/HAVCR2	8
BP	GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	8/232	112/18986	0.0714285714285714	5.84544334975369	5.72022212881486	7.03359703860648e-05	0.000508894432099514	0.000254184137346737	FCGR2A/MMP8/EPHB2/IL12B/PF4/CLEC7A/FCGR3A/HAVCR2	8
BP	GO:0042098	T cell proliferation	11/232	215/18986	0.0511627906976744	4.18696872493986	5.22703808008955	7.07205439341619e-05	0.000510611425921216	0.000255041746638311	PDE5A/PRKCQ/PLA2G5/TP53/CDKN2A/IGF2/IL12B/HLA-A/LIPA/PPP3CA/HAVCR2	11
BP	GO:0002429	immune response-activating cell surface receptor signaling pathway	14/232	336/18986	0.0416666666666667	3.40984195402299	4.95702511069926	7.0812108412367e-05	0.000510611425921216	0.000255041746638311	PDE4D/PDE4B/NR4A3/PRKCD/PRKCH/IKBKB/CHUK/LTF/BRAF/KLRK1/HLA-A/CLEC7A/LIPA/BCL2	14
BP	GO:0001569	branching involved in blood vessel morphogenesis	5/232	36/18986	0.138888888888889	11.3661398467433	6.92414324809334	7.22186593880673e-05	0.000519514538729875	0.000259488700478292	VEGFA/KDR/EDNRA/COL4A1/NRP1	5
BP	GO:0032069	regulation of nuclease activity	4/232	19/18986	0.210526315789474	17.2286751361162	7.87159755947058	7.28972692324427e-05	0.000519514538729875	0.000259488700478292	PDE3A/PRKCD/HSPA1A/GZMA	4
BP	GO:0060749	mammary gland alveolus development	4/232	19/18986	0.210526315789474	17.2286751361162	7.87159755947058	7.28972692324427e-05	0.000519514538729875	0.000259488700478292	VEGFA/DDR1/ESR1/AR	4
BP	GO:0060977	coronary vasculature morphogenesis	4/232	19/18986	0.210526315789474	17.2286751361162	7.87159755947058	7.28972692324427e-05	0.000519514538729875	0.000259488700478292	VEGFA/PDGFRB/TGFBR1/NRP1	4
BP	GO:0061377	mammary gland lobule development	4/232	19/18986	0.210526315789474	17.2286751361162	7.87159755947058	7.28972692324427e-05	0.000519514538729875	0.000259488700478292	VEGFA/DDR1/ESR1/AR	4
BP	GO:0071391	cellular response to estrogen stimulus	4/232	19/18986	0.210526315789474	17.2286751361162	7.87159755947058	7.28972692324427e-05	0.000519514538729875	0.000259488700478292	ESR1/ESR2/MDM2/AR	4
BP	GO:2000811	negative regulation of anoikis	4/232	19/18986	0.210526315789474	17.2286751361162	7.87159755947058	7.28972692324427e-05	0.000519514538729875	0.000259488700478292	NTRK2/ITGB1/BCL2L1/BCL2	4
BP	GO:1902105	regulation of leukocyte differentiation	14/232	337/18986	0.0415430267062315	3.39972372864013	4.94368464066673	7.30920871960767e-05	0.000520036214393385	0.000259749268623942	PRKCA/RHOA/INHBA/SMARCA4/MMP14/CDKN2A/BRD4/LTF/IL12B/BRAF/PF4/TNF/PPP3CA/PRKCZ	14
BP	GO:0072659	protein localization to plasma membrane	13/232	295/18986	0.0440677966101695	3.60634132086499	5.01797352886954	7.32377168906723e-05	0.000520206773130423	0.000259834459820203	ITGB1/PRKCH/IKBKB/MMP14/EPHB2/FLNA/LAMA5/SEC23A/INS/TNF/PRKCZ/AR/BCL2L1	13
BP	GO:0031032	actomyosin structure organization	11/232	216/18986	0.0509259259259259	4.16758461047254	5.2074523047188	7.37264109603298e-05	0.000521943929248957	0.000260702139837067	RHOA/APOA1/PDGFRB/PDGFRA/MYH9/ITGB1/MYH7/BRAF/TGFBR1/NRP1/PLEC	11
BP	GO:0034764	positive regulation of transmembrane transport	11/232	216/18986	0.0509259259259259	4.16758461047254	5.2074523047188	7.37264109603298e-05	0.000521943929248957	0.000260702139837067	SNCA/NR4A3/ITGB1/EDNRA/EPHB2/FLNA/F2/BRAF/INS/PPP3CA/CA2	11
BP	GO:0061756	leukocyte adhesion to vascular endothelial cell	6/232	58/18986	0.103448275862069	8.46581450653983	6.33346195155099	7.42901044682062e-05	0.000525065267282727	0.000262261195243132	RHOA/ITGB1/ITGB2/ITGB7/TNF/ALOX5	6
BP	GO:0050671	positive regulation of lymphocyte proliferation	9/232	145/18986	0.0620689655172414	5.0794887039239	5.48453861527082	7.47502356751416e-05	0.000527445557338128	0.000263450109753105	PRKCQ/EPHB2/IGF2/IL12B/HLA-A/FCGR3A/PPP3CA/HAVCR2/BCL2	9
BP	GO:0001523	retinoid metabolic process	7/232	84/18986	0.0833333333333333	6.81968390804598	5.94548787631207	7.57222401474966e-05	0.000533423886113172	0.000266436183576295	CYP3A4/CYP1A1/CYP1A2/CYP2D6/CYP1B1/CYP2S1/LIPA	7
BP	GO:0042326	negative regulation of phosphorylation	12/232	256/18986	0.046875	3.83607219827586	5.08125176580096	7.73582290409722e-05	0.000544052281873679	0.000271744886987764	SNCA/PDE4D/INHBA/PRKCD/PRKCH/CDKN1B/CDKN2A/EPHB2/NTRK3/PPIA/PRKCZ/MAPT	12
BP	GO:0031348	negative regulation of defense response	13/232	297/18986	0.0437710437710438	3.58205619412516	4.98830752721083	7.84099559607725e-05	0.000550543467468413	0.000274987124093695	APOA1/PRKCD/RORA/PLA2G10/IL12B/MICA/HLA-A/GRN/INS/HAVCR2/HGF/AHR/ALOX5	13
BP	GO:1900180	regulation of protein localization to nucleus	9/232	146/18986	0.0616438356164384	5.04469768540387	5.45662844350306	7.88268888598809e-05	0.000552563568466969	0.000275996130279031	PRKCD/CDK1/CDKN2A/LMNA/FLNA/F2/INS/POLR1A/PTGS2	9
BP	GO:1903532	positive regulation of secretion by cell	13/232	298/18986	0.0436241610738255	3.57003587132608	4.97357007973903	8.11127981985316e-05	0.000567656833219183	0.000283534960022087	SNCA/PRKCA/CPB2/ITGB2/INHBA/PLA2G10/F2/FGA/FGB/FGG/PPIA/INS/SLC6A4	13
BP	GO:0002720	positive regulation of cytokine production involved in immune response	7/232	85/18986	0.0823529411764706	6.7394523326572	5.89847662205884	8.16706151783244e-05	0.000570116056701851	0.000284763300440169	NR4A3/IL1R1/IL18R1/HTR2A/HLA-A/CLEC7A/PRKCZ	7
BP	GO:0019748	secondary metabolic process	6/232	59/18986	0.101694915254237	8.32232612507306	6.26522280242229	8.18641858781423e-05	0.000570116056701851	0.000284763300440169	CYP3A4/CYP1A1/CYP1A2/CYP2D6/CYP1B1/BCL2	6
BP	GO:0038093	Fc receptor signaling pathway	6/232	59/18986	0.101694915254237	8.32232612507306	6.26522280242229	8.18641858781423e-05	0.000570116056701851	0.000284763300440169	NR4A3/PRKCD/PRKCQ/IKBKB/FCGR2A/FCGR3A	6
BP	GO:0034110	regulation of homotypic cell-cell adhesion	5/232	37/18986	0.135135135135135	11.0589468779124	6.81181063210357	8.26771370048928e-05	0.000572978019178155	0.000286192802154615	PRKCA/PRKCD/PRKCQ/PLAUR/HTR2A	5
BP	GO:0051353	positive regulation of oxidoreductase activity	5/232	37/18986	0.135135135135135	11.0589468779124	6.81181063210357	8.26771370048928e-05	0.000572978019178155	0.000286192802154615	SNCA/ESR1/INS/TNF/NPR3	5
BP	GO:1904385	cellular response to angiotensin	5/232	37/18986	0.135135135135135	11.0589468779124	6.81181063210357	8.26771370048928e-05	0.000572978019178155	0.000286192802154615	PRKCA/INHBA/PRKCD/PPP3CA/CA2	5
BP	GO:0045927	positive regulation of growth	12/232	259/18986	0.0463320463320463	3.79163892956996	5.03126694164762	8.64257739547802e-05	0.000597988041149903	0.000298684883928205	VEGFA/PLAA/CDK1/MMP14/IGF2/F2/TGFBR1/NRP1/INS/MAPT/BCL2/SLC6A3	12
BP	GO:1902806	regulation of cell cycle G1/S phase transition	11/232	220/18986	0.05	4.09181034482759	5.13027526374668	8.68704489662526e-05	0.0006000937637798	0.000299736656666145	CDK2/INHBA/ATM/CDKN1B/ADAMTS1/SMARCA4/CYP1A1/TP53/CDKN2A/MDM2/BCL2	11
BP	GO:0008203	cholesterol metabolic process	9/232	148/18986	0.0608108108108108	4.97652609506058	5.40156536018956	8.75426876301752e-05	0.000602067303600139	0.000300722406332697	HMGCR/APOA1/CYP3A4/CYP1A2/CYP2C9/CYP2D6/ABCA1/PON1/LIPA	9
BP	GO:0055123	digestive system development	9/232	148/18986	0.0608108108108108	4.97652609506058	5.40156536018956	8.75426876301752e-05	0.000602067303600139	0.000300722406332697	PDGFRA/CXCL8/CYP1A1/EPHB3/IGF2/COL3A1/TNF/NPR2/BCL2	9
BP	GO:0071248	cellular response to metal ion	10/232	183/18986	0.0546448087431694	4.47192387412851	5.24909585261555	8.75785460335094e-05	0.000602067303600139	0.000300722406332697	SNCA/FABP4/CDKN1B/CYP1A1/CYP1A2/MAP1LC3A/BRAF/HSPA8/ALOX15/PTGS2	10
BP	GO:0071868	cellular response to monoamine stimulus	6/232	60/18986	0.1	8.18362068965517	6.1985760978339	9.00407579419445e-05	0.000617010065640632	0.000308186062523963	NR4A3/HTR3A/HTR3B/FLNA/HTR1A/HTR2A	6
BP	GO:0071870	cellular response to catecholamine stimulus	6/232	60/18986	0.1	8.18362068965517	6.1985760978339	9.00407579419445e-05	0.000617010065640632	0.000308186062523963	NR4A3/HTR3A/HTR3B/FLNA/HTR1A/HTR2A	6
BP	GO:2000318	positive regulation of T-helper 17 type immune response	4/232	20/18986	0.2	16.3672413793103	7.64760370675913	9.02508097603425e-05	0.000617459940056359	0.000308410767164185	PRKCQ/BRD4/IL12B/CLEC7A	4
BP	GO:1901292	nucleoside phosphate catabolic process	10/232	184/18986	0.0543478260869565	4.44761994002998	5.22671245860391	9.1636387834489e-05	0.000625938010192132	0.000312645419398315	PDE5A/PDE4A/PDE4D/PDE4B/PDE8B/ALDOA/COL6A1/HTR2A/INS/LIPA	10
BP	GO:0071392	cellular response to estradiol stimulus	5/232	38/18986	0.131578947368421	10.7679219600726	6.70370089610688	9.42628349210884e-05	0.000641827837774799	0.000320582118764479	MMP2/CCNA2/ESR1/ESR2/SRD5A1	5
BP	GO:2000316	regulation of T-helper 17 type immune response	5/232	38/18986	0.131578947368421	10.7679219600726	6.70370089610688	9.42628349210884e-05	0.000641827837774799	0.000320582118764479	PRKCQ/EPHB2/BRD4/IL12B/CLEC7A	5
BP	GO:1903076	regulation of protein localization to plasma membrane	8/232	117/18986	0.0683760683760684	5.5956380783967	5.54583118115598	9.57443850598315e-05	0.000650879158212781	0.00032510309980152	ITGB1/PRKCH/MMP14/EPHB2/INS/TNF/AR/BCL2L1	8
BP	GO:0043123	positive regulation of canonical NF-kappaB signal transduction	11/232	223/18986	0.0493273542600897	4.0367635688882	5.07358113981981	9.79991420398245e-05	0.000665149732321094	0.000332231009521811	VEGFA/RHOA/EDNRA/IKBKB/CHUK/XIAP/FLNA/BRD4/LTF/CLEC7A/TNF	11
BP	GO:0031102	neuron projection regeneration	6/232	61/18986	0.0983606557377049	8.04946297343132	6.13345727762808	9.88541400671461e-05	0.000668829593239109	0.000334069037635309	MMP2/FLNA/LAMB2/BRAF/GRN/BCL2	6
BP	GO:0032233	positive regulation of actin filament bundle assembly	6/232	61/18986	0.0983606557377049	8.04946297343132	6.13345727762808	9.88541400671461e-05	0.000668829593239109	0.000334069037635309	RHOA/APOA1/FLNA/BRAF/TGFBR1/NRP1	6
BP	GO:0051495	positive regulation of cytoskeleton organization	10/232	186/18986	0.0537634408602151	4.39979606970708	5.18242173769665	0.000100231966618074	0.00067708039377391	0.000338190172558531	RHOA/APOA1/HSPA1A/CDKN1B/FLNA/BRAF/TGFBR1/NRP1/MAPT/ALOX15	10
BP	GO:0120161	regulation of cold-induced thermogenesis	9/232	151/18986	0.0596026490066225	4.87765471568851	5.32080243528795	0.000102125106705319	0.000688780688126093	0.000344034271135799	VEGFA/FABP4/THRA/SMARCA4/IL18R1/LNPEP/LAMA4/ADAMTS5/NPR3	9
BP	GO:0043122	regulation of canonical NF-kappaB signal transduction	13/232	305/18986	0.0426229508196721	3.48810062182024	4.87214423387085	0.000102397992300892	0.000689533567052935	0.000344410321389987	VEGFA/RHOA/EDNRA/ESR1/RORA/IKBKB/CHUK/XIAP/FLNA/BRD4/LTF/CLEC7A/TNF	13
BP	GO:0050863	regulation of T cell activation	15/232	393/18986	0.0381679389312977	3.12351934719663	4.73129579040118	0.000104662766668181	0.00070367608533513	0.00035147426939712	PDE5A/RHOA/PRKCQ/SMARCA4/PLA2G5/CDKN2A/BRD4/IGF2/IL12B/BRAF/KLRK1/HLA-A/PPP3CA/HAVCR2/PRKCZ	15
BP	GO:0050974	detection of mechanical stimulus involved in sensory perception	5/232	39/18986	0.128205128205128	10.4918213969938	6.59954464295019	0.000107056428418751	0.000718639384487563	0.000358948183527464	NTRK1/COL11A1/HTR2A/TNF/TRPA1	5
BP	GO:0031333	negative regulation of protein-containing complex assembly	9/232	152/18986	0.0592105263157895	4.84556488203267	5.29435418218878	0.000107416784457559	0.000719928166677934	0.000359591908372195	SNCA/CRBN/PRKCD/THRA/HSPA5/RAF1/HSPA8/PRKCZ/DYRK1A	9
BP	GO:0033209	tumor necrosis factor-mediated signaling pathway	8/232	119/18986	0.0672268907563025	5.50159374094465	5.4788661622617	0.000107836642352035	0.000721611084033334	0.000360432497046831	APOA1/IKBKB/CHUK/MMP8/HSPA1A/XIAP/TP53/TNF	8
BP	GO:0006163	purine nucleotide metabolic process	16/232	440/18986	0.0363636363636364	2.97586206896552	4.66401750700244	0.000108330154244571	0.000723125184995786	0.000361188764796526	PDE5A/PDE4A/PDE4D/PDE4B/PDE8B/RORA/HSPA1A/TP53/ALDOA/MYH7/COL6A1/HTR2A/HSPA8/INS/LIPA/NPR2	16
BP	GO:0034762	regulation of transmembrane transport	17/232	487/18986	0.0349075975359343	2.85670537421228	4.61674286030327	0.00010840113273674	0.000723125184995786	0.000361188764796526	SNCA/CRBN/PDE4D/PDE4B/NR4A3/ITGB1/MMP9/EDNRA/EPHB2/FLNA/F2/BRAF/INS/TNF/PPP3CA/CA2/BCL2	17
BP	GO:0009791	post-embryonic development	7/232	89/18986	0.0786516853932584	6.43655559860519	5.71774447579315	0.000109400473387618	0.000727521655062915	0.000363384727025419	VEGFA/KDR/NR4A2/ATM/CYP1A2/TGFBR1/BCL2	7
BP	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	7/232	89/18986	0.0786516853932584	6.43655559860519	5.71774447579315	0.000109400473387618	0.000727521655062915	0.000363384727025419	CDK2/INHBA/ATM/CDKN1B/TP53/MDM2/BCL2	7
BP	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	4/232	21/18986	0.19047619047619	15.5878489326765	7.43920999902877	0.000110421309441617	0.000729770508767159	0.000364507991307313	ATM/CDKN1B/TP53/MDM2	4
BP	GO:0032930	positive regulation of superoxide anion generation	4/232	21/18986	0.19047619047619	15.5878489326765	7.43920999902877	0.000110421309441617	0.000729770508767159	0.000364507991307313	ITGB2/PRKCD/CLEC7A/MAPT	4
BP	GO:0042359	vitamin D metabolic process	4/232	21/18986	0.19047619047619	15.5878489326765	7.43920999902877	0.000110421309441617	0.000729770508767159	0.000364507991307313	CYP3A4/CYP1A1/CYP2R1/TNF	4
BP	GO:2001044	regulation of integrin-mediated signaling pathway	4/232	21/18986	0.19047619047619	15.5878489326765	7.43920999902877	0.000110421309441617	0.000729770508767159	0.000364507991307313	FLNA/LAMA1/LAMB1/LAMB2	4
BP	GO:0106106	cold-induced thermogenesis	9/232	153/18986	0.0588235294117647	4.81389452332657	5.26813599548065	0.000112936308481168	0.000745240208434376	0.000372234843905605	VEGFA/FABP4/THRA/SMARCA4/IL18R1/LNPEP/LAMA4/ADAMTS5/NPR3	9
BP	GO:0042303	molting cycle	8/232	120/18986	0.0666666666666667	5.45574712643678	5.44594913852549	0.000114340543673137	0.000751427335683128	0.000375325209024929	INHBA/PLA2G10/COL6A1/LAMA5/PDGFA/TNF/BCL2/PTGS2	8
BP	GO:0042633	hair cycle	8/232	120/18986	0.0666666666666667	5.45574712643678	5.44594913852549	0.000114340543673137	0.000751427335683128	0.000375325209024929	INHBA/PLA2G10/COL6A1/LAMA5/PDGFA/TNF/BCL2/PTGS2	8
BP	GO:0007565	female pregnancy	10/232	189/18986	0.0529100529100529	4.32995803685459	5.11714507127157	0.000114401121498998	0.000751427335683128	0.000375325209024929	VEGFA/MMP2/DDR1/MMP9/ESR1/LNPEP/HAVCR2/AR/BCL2/PTGS2	10
BP	GO:0002285	lymphocyte activation involved in immune response	11/232	227/18986	0.0484581497797357	3.96563117119854	4.99951138932134	0.000114715555247988	0.000752336985031283	0.00037577956344554	ITGAL/ICAM1/RORA/TP53/IL18R1/BRD4/IL12B/TNFSF13/FCGR3A/HAVCR2/PRKCZ	11
BP	GO:0071867	response to monoamine	6/232	63/18986	0.0952380952380952	7.79392446633826	6.00756296804336	0.000118534286330272	0.000774846425612501	0.000387022647227553	NR4A3/HTR3A/HTR3B/FLNA/HTR1A/HTR2A	6
BP	GO:0071869	response to catecholamine	6/232	63/18986	0.0952380952380952	7.79392446633826	6.00756296804336	0.000118534286330272	0.000774846425612501	0.000387022647227553	NR4A3/HTR3A/HTR3B/FLNA/HTR1A/HTR2A	6
BP	GO:1903531	negative regulation of secretion by cell	9/232	154/18986	0.0584415584415584	4.7826354679803	5.24214422604319	0.000118691395878435	0.000774846425612501	0.000387022647227553	SNCA/HMGCR/PDE8B/INHBA/MAOB/IL12B/BRAF/INS/PPP3CA	9
BP	GO:0051591	response to cAMP	7/232	91/18986	0.0769230769230769	6.29509283819629	5.63148801684836	0.000125889429178017	0.000820584145068903	0.000409867862327016	PDE4D/CYP1B1/COL1A1/BRAF/AHR/SRD5A1/SLC6A3	7
BP	GO:0002440	production of molecular mediator of immune response	11/232	230/18986	0.0478260869565217	3.91390554722639	4.94506054825096	0.00012879637714759	0.000838254655529826	0.000418693982588257	NR4A3/APOA1/IL1R1/EPHB2/IL18R1/HTR2A/HLA-A/TNFSF13/CLEC7A/TNF/PRKCZ	11
BP	GO:0002011	morphogenesis of an epithelial sheet	6/232	64/18986	0.09375	7.67214439655172	5.94667551966318	0.000129475372697492	0.000840116378838357	0.000419623881803709	RHOA/DDR1/ITGB1/FLNA/LAMA1/COL5A1	6
BP	GO:0048599	oocyte development	6/232	64/18986	0.09375	7.67214439655172	5.94667551966318	0.000129475372697492	0.000840116378838357	0.000419623881803709	PDE5A/PDE3A/EDNRA/ATM/NPR2/BCL2	6
BP	GO:0060538	skeletal muscle organ development	10/232	192/18986	0.0520833333333333	4.26230244252874	5.05321249933873	0.000130229144752405	0.000843727004486795	0.00042142732807437	RHOA/EGR1/EPHB1/IGF2/NR4A1/COL6A1/HSPA8/PPP3CA/BCL2/PLEC	10
BP	GO:0008037	cell recognition	9/232	156/18986	0.0576923076923077	4.72131962864721	5.19082574829175	0.000130940048494331	0.000847049390864994	0.000423086803718446	PLA2G5/ALDOA/EPHB2/EPHB3/EPHB1/B4GALT1/NRP1/CLEC7A/HAVCR2	9
BP	GO:0006837	serotonin transport	4/232	22/18986	0.181818181818182	14.8793103448276	7.24463636043525	0.000133670650927654	0.00086210513328303	0.000430606891692006	SNCA/MAOB/HTR1A/SLC6A4	4
BP	GO:0048485	sympathetic nervous system development	4/232	22/18986	0.181818181818182	14.8793103448276	7.24463636043525	0.000133670650927654	0.00086210513328303	0.000430606891692006	NTRK1/EDNRA/NRP2/NRP1	4
BP	GO:0060021	roof of mouth development	7/232	92/18986	0.0760869565217391	6.22666791604198	5.58932293918704	0.000134859318117168	0.000865853519923439	0.000432479147241558	PDGFRA/INHBA/EPHB2/EPHB3/COL2A1/COL11A2/TGFBR1	7
BP	GO:2000243	positive regulation of reproductive process	7/232	92/18986	0.0760869565217391	6.22666791604198	5.58932293918704	0.000134859318117168	0.000865853519923439	0.000432479147241558	VEGFA/PDE5A/PDE3A/INHBA/PLA2G10/NPR2/AR	7
BP	GO:2000628	regulation of miRNA metabolic process	7/232	92/18986	0.0760869565217391	6.22666791604198	5.58932293918704	0.000134859318117168	0.000865853519923439	0.000432479147241558	VEGFA/EGR1/ESR1/SMARCA4/TP53/TNF/AR	7
BP	GO:0006936	muscle contraction	14/232	358/18986	0.0391061452513966	3.2002985937199	4.6745774232113	0.000138214269379467	0.000886063292153823	0.000442573585687585	TPM3/PDE5A/PDE4D/PDE4B/RHOA/EDNRA/CHUK/ALDOA/FLNA/MYH7/NR4A1/HTR2A/TNF/PTGS2	14
BP	GO:0045926	negative regulation of growth	11/232	232/18986	0.0474137931034483	3.88016498216409	4.9092679843449	0.000138980030140046	0.000888308832404836	0.00044369519495579	INHBA/HSPA1A/ESR2/CDKN1B/SMARCA4/TP53/CDKN2A/NRP1/HNF4A/BCL2/SLC6A4	11
BP	GO:0048588	developmental cell growth	11/232	232/18986	0.0474137931034483	3.88016498216409	4.9092679843449	0.000138980030140046	0.000888308832404836	0.00044369519495579	VEGFA/PLAA/DDR1/ITGB1/EDNRA/NRP2/LAMB2/NRP1/NPR2/PRKCZ/MAPT	11
BP	GO:0042770	signal transduction in response to DNA damage	10/232	194/18986	0.0515463917525773	4.21836118023463	5.01131245220789	0.000141777780397934	0.000903489998482214	0.000451277929919849	CDK2/ATM/ATR/CDK1/CDKN1B/TP53/CDKN2A/MDM2/BRD4/DYRK1A	10
BP	GO:1905475	regulation of protein localization to membrane	10/232	194/18986	0.0515463917525773	4.21836118023463	5.01131245220789	0.000141777780397934	0.000903489998482214	0.000451277929919849	ITGB1/ITGB2/PRKCH/MMP14/EPHB2/INS/TNF/PRKCZ/AR/BCL2L1	10
BP	GO:0031640	killing of cells of another organism	8/232	124/18986	0.0645161290322581	5.2797552836485	5.31787649007333	0.000143688233755996	0.000912943369302582	0.000455999728303614	PLA2G2A/CXCL8/LTF/F2/GZMA/PF4/MICA/CLEC7A	8
BP	GO:0141061	disruption of cell in another organism	8/232	124/18986	0.0645161290322581	5.2797552836485	5.31787649007333	0.000143688233755996	0.000912943369302582	0.000455999728303614	PLA2G2A/CXCL8/LTF/F2/GZMA/PF4/MICA/CLEC7A	8
BP	GO:0035264	multicellular organism growth	9/232	158/18986	0.0569620253164557	4.66155608904409	5.14037114689969	0.000144228184959857	0.000913658842797552	0.000456357095179024	ATM/TP53/IGF2/COL3A1/NPR2/AR/BCL2/SLC6A3/PLEC	9
BP	GO:0044839	cell cycle G2/M phase transition	9/232	158/18986	0.0569620253164557	4.66155608904409	5.14037114689969	0.000144228184959857	0.000913658842797552	0.000456357095179024	CDC7/CDK2/CCNA2/SKP2/ATM/ATR/CDK1/TP53/BRD4	9
BP	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	12/232	274/18986	0.0437956204379562	3.58406745532343	4.79205022045265	0.000146802354721435	0.0009272184177088	0.000463129872859818	PDE4A/PDE3A/PDE4D/PDE4B/PDE3B/PRKCA/PSAP/EDNRA/FLNA/ABCA1/HTR1A/PF4	12
BP	GO:0090068	positive regulation of cell cycle process	12/232	274/18986	0.0437956204379562	3.58406745532343	4.79205022045265	0.000146802354721435	0.0009272184177088	0.000463129872859818	CDC7/RHOA/PDGFRB/CDK1/ADAMTS1/CYP1A1/MDM2/BRD4/IGF2/INS/TNF/NPR2	12
BP	GO:0007005	mitochondrion organization	16/232	452/18986	0.0353982300884956	2.89685688129387	4.53964131473778	0.000147505138502167	0.000929833725052942	0.000464436174519329	KDR/SNCA/MMP9/EDNRA/HSPA1A/PLAUR/TP53/CDKN2A/LMNA/COL6A1/LIPA/HGF/MAPT/BCL2L1/BCL2/PLEC	16
BP	GO:1902107	positive regulation of leukocyte differentiation	10/232	195/18986	0.0512820512820513	4.19672855879752	4.99057351768304	0.00014786878695884	0.000929833725052942	0.000464436174519329	PRKCA/RHOA/SMARCA4/MMP14/BRD4/IL12B/PF4/TNF/PPP3CA/PRKCZ	10
BP	GO:1903708	positive regulation of hemopoiesis	10/232	195/18986	0.0512820512820513	4.19672855879752	4.99057351768304	0.00014786878695884	0.000929833725052942	0.000464436174519329	PRKCA/RHOA/SMARCA4/MMP14/BRD4/IL12B/PF4/TNF/PPP3CA/PRKCZ	10
BP	GO:0007612	learning	9/232	159/18986	0.0566037735849057	4.63223812621991	5.11545950363001	0.000151283337928588	0.000949908301002412	0.000474463084716137	NTRK2/HMGCR/PDE8B/ITGB1/EPHB2/HTR2A/BRAF/PTGS2/SLC6A4	9
BP	GO:0014044	Schwann cell development	5/232	42/18986	0.119047619047619	9.74240558292282	6.3084416542623	0.000153532477033258	0.000956989562328605	0.000478000054641509	NTRK2/COL6A1/LAMB2/RAF1/PLEC	5
BP	GO:0044319	wound healing, spreading of cells	5/232	42/18986	0.119047619047619	9.74240558292282	6.3084416542623	0.000153532477033258	0.000956989562328605	0.000478000054641509	RHOA/DDR1/ITGB1/FLNA/COL5A1	5
BP	GO:0045429	positive regulation of nitric oxide biosynthetic process	5/232	42/18986	0.119047619047619	9.74240558292282	6.3084416542623	0.000153532477033258	0.000956989562328605	0.000478000054641509	ESR1/KLRK1/CLEC7A/TNF/PTGS2	5
BP	GO:0090505	epiboly involved in wound healing	5/232	42/18986	0.119047619047619	9.74240558292282	6.3084416542623	0.000153532477033258	0.000956989562328605	0.000478000054641509	RHOA/DDR1/ITGB1/FLNA/COL5A1	5
BP	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	6/232	66/18986	0.0909090909090909	7.43965517241379	5.82876239061055	0.000153753935762337	0.000956989562328605	0.000478000054641509	MMP2/PRKCD/CYP1B1/PPIA/INS/BCL2	6
BP	GO:0045428	regulation of nitric oxide biosynthetic process	6/232	66/18986	0.0909090909090909	7.43965517241379	5.82876239061055	0.000153753935762337	0.000956989562328605	0.000478000054641509	ESR1/GLA/KLRK1/CLEC7A/TNF/PTGS2	6
BP	GO:1900182	positive regulation of protein localization to nucleus	7/232	94/18986	0.074468085106383	6.09418561995598	5.50683496514768	0.00015435535503317	0.00095794411918989	0.000478476839603241	PRKCD/CDK1/CDKN2A/FLNA/F2/INS/PTGS2	7
BP	GO:1904705	regulation of vascular associated smooth muscle cell proliferation	7/232	94/18986	0.074468085106383	6.09418561995598	5.50683496514768	0.00015435535503317	0.00095794411918989	0.000478476839603241	MMP2/NR4A3/MMP9/CDKN1B/ADAMTS1/MDM2/TNF	7
BP	GO:1990778	protein localization to cell periphery	14/232	362/18986	0.0386740331491713	3.16493617831968	4.62556980292105	0.000155137404024126	0.000961402231314729	0.000480204107955686	SNCA/ITGB1/PRKCH/IKBKB/MMP14/EPHB2/FLNA/LAMA5/SEC23A/INS/TNF/PRKCZ/AR/BCL2L1	14
BP	GO:0019722	calcium-mediated signaling	11/232	235/18986	0.0468085106382979	3.83063096111519	4.85632008941141	0.000155537073666744	0.000962484120114323	0.000480744493060893	PDGFRB/PDGFRA/CXCL8/CXCR1/CLEC7A/FCGR3A/TNF/PPP3CA/CXCR2/TRPA1/MAPT	11
BP	GO:0031346	positive regulation of cell projection organization	14/232	363/18986	0.0385674931129477	3.15621734587252	4.61342392653211	0.000159638187781812	0.000983217945268578	0.0004911006870538	VEGFA/NTRK1/NTRK2/DDR1/EPHB2/FLNA/AP2A1/NTRK3/BRAF/TGFBR1/NRP1/GRN/INS/MAPT	14
BP	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	4/232	23/18986	0.173913043478261	14.232383808096	7.06237577886472	0.000160267284343358	0.000983217945268578	0.0004911006870538	ERAP1/ERAP2/MICA/HLA-A	4
BP	GO:0032928	regulation of superoxide anion generation	4/232	23/18986	0.173913043478261	14.232383808096	7.06237577886472	0.000160267284343358	0.000983217945268578	0.0004911006870538	ITGB2/PRKCD/CLEC7A/MAPT	4
BP	GO:0046058	cAMP metabolic process	4/232	23/18986	0.173913043478261	14.232383808096	7.06237577886472	0.000160267284343358	0.000983217945268578	0.0004911006870538	PDE4A/PDE4D/PDE4B/PDE8B	4
BP	GO:0051354	negative regulation of oxidoreductase activity	4/232	23/18986	0.173913043478261	14.232383808096	7.06237577886472	0.000160267284343358	0.000983217945268578	0.0004911006870538	SNCA/GLA/GZMA/INS	4
BP	GO:0098743	cell aggregation	4/232	23/18986	0.173913043478261	14.232383808096	7.06237577886472	0.000160267284343358	0.000983217945268578	0.0004911006870538	THRA/LTF/COL2A1/COL11A1	4
BP	GO:0007411	axon guidance	11/232	236/18986	0.0466101694915254	3.81439947399182	4.83886430802397	0.000161415991019101	0.000988846386243086	0.000493911997855158	VEGFA/NTRK1/EDNRA/PRKCQ/NRP2/PLA2G10/EPHB2/EPHB3/EPHB1/LAMB2/NRP1	11
BP	GO:0030217	T cell differentiation	13/232	320/18986	0.040625	3.32459590517241	4.66443627542715	0.000164791147418401	0.0010074584506009	0.000503208408317964	RHOA/EGR1/RORA/SMARCA4/TP53/CDKN2A/IL18R1/BRD4/IL12B/BRAF/LIPA/PRKCZ/BCL2	13
BP	GO:0055006	cardiac cell development	7/232	95/18986	0.0736842105263158	6.03003629764065	5.46648027046472	0.0001649253777878	0.0010074584506009	0.000503208408317964	VEGFA/PDGFRB/PDGFRA/INHBA/CDK1/LMNA/PLEC	7
BP	GO:0097485	neuron projection guidance	11/232	237/18986	0.0464135021097046	3.79830496144333	4.82150363257354	0.000167482678563818	0.00102016555900148	0.000509555393435577	VEGFA/NTRK1/EDNRA/PRKCQ/NRP2/PLA2G10/EPHB2/EPHB3/EPHB1/LAMB2/NRP1	11
BP	GO:0010466	negative regulation of peptidase activity	10/232	198/18986	0.0505050505050505	4.13314176245211	4.92918027813337	0.000167482746122319	0.00102016555900148	0.000509555393435577	VEGFA/SNCA/MMP9/XIAP/PLAUR/LTF/COL6A3/RAF1/TNF/PTGS2	10
BP	GO:0045787	positive regulation of cell cycle	14/232	365/18986	0.0383561643835616	3.1389230042513	4.5892574424295	0.000168979670553175	0.00102781944706313	0.000513378380702841	CDC7/PRKCA/RHOA/PDGFRB/CDK1/ADAMTS1/CYP1A1/MDM2/BRD4/IGF2/INS/TNF/NPR2/SLC6A4	14
BP	GO:0141060	disruption of anatomical structure in another organism	8/232	127/18986	0.062992125984252	5.1550366549009	5.22540223830471	0.000169555708629838	0.00102985825298464	0.000514396729679936	PLA2G2A/CXCL8/LTF/F2/GZMA/PF4/MICA/CLEC7A	8
BP	GO:0090504	epiboly	5/232	43/18986	0.116279069767442	9.51583801122695	6.21784049775778	0.00017201896090753	0.00104185988221048	0.000520391339915579	RHOA/DDR1/ITGB1/FLNA/COL5A1	5
BP	GO:1904407	positive regulation of nitric oxide metabolic process	5/232	43/18986	0.116279069767442	9.51583801122695	6.21784049775778	0.00017201896090753	0.00104185988221048	0.000520391339915579	ESR1/KLRK1/CLEC7A/TNF/PTGS2	5
BP	GO:0001942	hair follicle development	7/232	96/18986	0.0729166666666667	5.96722341954023	5.4266981992243	0.000176073605586724	0.00106340499645315	0.00053115275904767	INHBA/PLA2G10/COL6A1/LAMA5/PDGFA/TNF/BCL2	7
BP	GO:1990874	vascular associated smooth muscle cell proliferation	7/232	96/18986	0.0729166666666667	5.96722341954023	5.4266981992243	0.000176073605586724	0.00106340499645315	0.00053115275904767	MMP2/NR4A3/MMP9/CDKN1B/ADAMTS1/MDM2/TNF	7
BP	GO:0002698	negative regulation of immune effector process	8/232	128/18986	0.0625	5.11476293103448	5.19522456971285	0.000178984801353525	0.00107794226843334	0.000538413879831434	APOA1/MICA/HLA-A/GRN/INS/TNF/HAVCR2/AHR	8
BP	GO:0030282	bone mineralization	8/232	128/18986	0.0625	5.11476293103448	5.19522456971285	0.000178984801353525	0.00107794226843334	0.000538413879831434	MMP13/AHSG/LTF/COL1A2/COL6A1/ALOX5/ALOX15/PTGS2	8
BP	GO:0009994	oocyte differentiation	6/232	68/18986	0.0882352941176471	7.22084178498986	5.71568569787181	0.000181500159552932	0.00109002062113531	0.000544446812142075	PDE5A/PDE3A/EDNRA/ATM/NPR2/BCL2	6
BP	GO:0080164	regulation of nitric oxide metabolic process	6/232	68/18986	0.0882352941176471	7.22084178498986	5.71568569787181	0.000181500159552932	0.00109002062113531	0.000544446812142075	ESR1/GLA/KLRK1/CLEC7A/TNF/PTGS2	6
BP	GO:0019915	lipid storage	7/232	97/18986	0.0721649484536082	5.90570565232847	5.387474253369	0.000187823408833134	0.00112641359911709	0.000562624487373484	HEXA/APOA1/PLA2G10/GLA/ABCA1/LIPA/TNF	7
BP	GO:0032770	positive regulation of monooxygenase activity	4/232	24/18986	0.166666666666667	13.639367816092	6.89114263935009	0.000190485663086157	0.00114077968537312	0.000569800103791556	ESR1/INS/TNF/NPR3	4
BP	GO:0044409	symbiont entry into host	9/232	164/18986	0.0548780487804878	4.49101135407906	4.99393215709541	0.000191029783823286	0.0011424382596201	0.000570628533496427	ITGB1/ICAM1/ITGB7/CXCL8/HSPA1A/CDK1/ANPEP/HTR2A/NRP1	9
BP	GO:0002833	positive regulation of response to biotic stimulus	15/232	416/18986	0.0360576923076923	2.95082476790451	4.47467308392838	0.000194741612335007	0.00116138791400905	0.000580093564453835	PRKCA/ESR1/IKBKB/CHUK/HSPA1A/XIAP/PLA2G5/LTF/IL12B/HSPA8/KLRK1/GRN/CLEC7A/TNF/HAVCR2	15
BP	GO:0030900	forebrain development	15/232	416/18986	0.0360576923076923	2.95082476790451	4.47467308392838	0.000194741612335007	0.00116138791400905	0.000580093564453835	NTRK2/NR4A2/RHOA/KCNA2/INHBA/NRP2/EPHB2/EPHB3/FLNA/COL3A1/LAMB1/HSPA8/NRP1/SRD5A1/SLC6A3	15
BP	GO:0034605	cellular response to heat	6/232	69/18986	0.0869565217391304	7.11619190404798	5.66085270009704	0.000196780098648276	0.00117162594075249	0.000585207285162426	ATM/ATR/HSPA1A/HSPA8/MAPT/PTGS2	6
BP	GO:0002520	immune system development	10/232	202/18986	0.0495049504950495	4.05129737111642	4.84918236556738	0.000197006326333265	0.00117162594075249	0.000585207285162426	ATM/TP53/EPHB3/RAF1/BRAF/TGFBR1/TNFSF13/LIPA/HAVCR2/BCL2	10
BP	GO:0019079	viral genome replication	8/232	130/18986	0.0615384615384615	5.03607427055703	5.13580325414542	0.000199138711916414	0.00118266268354804	0.000590719950991818	DDB1/EEF1A1/CXCL8/LTF/PPIA/HSPA8/TNF/BCL2	8
BP	GO:0001910	regulation of leukocyte mediated cytotoxicity	7/232	98/18986	0.0714285714285714	5.84544334975369	5.34879444933166	0.000200198736176817	0.00118566453724663	0.00059221932599907	ICAM1/IL12B/HSPA8/KLRK1/MICA/HLA-A/HAVCR2	7
BP	GO:1902807	negative regulation of cell cycle G1/S phase transition	7/232	98/18986	0.0714285714285714	5.84544334975369	5.34879444933166	0.000200198736176817	0.00118566453724663	0.00059221932599907	CDK2/INHBA/ATM/CDKN1B/TP53/MDM2/BCL2	7
BP	GO:0001820	serotonin secretion	3/232	10/18986	0.3	24.5508620689655	8.28527275985808	0.000202858994502622	0.00118662798973079	0.000592700554173547	MAOB/HTR1A/SLC6A4	3
BP	GO:0002536	respiratory burst involved in inflammatory response	3/232	10/18986	0.3	24.5508620689655	8.28527275985808	0.000202858994502622	0.00118662798973079	0.000592700554173547	GRN/INS/LIPA	3
BP	GO:0019614	catechol-containing compound catabolic process	3/232	10/18986	0.3	24.5508620689655	8.28527275985808	0.000202858994502622	0.00118662798973079	0.000592700554173547	MAOA/MAOB/SLC6A3	3
BP	GO:0031652	positive regulation of heat generation	3/232	10/18986	0.3	24.5508620689655	8.28527275985808	0.000202858994502622	0.00118662798973079	0.000592700554173547	HTR2A/TNF/PTGS2	3
BP	GO:0034351	negative regulation of glial cell apoptotic process	3/232	10/18986	0.3	24.5508620689655	8.28527275985808	0.000202858994502622	0.00118662798973079	0.000592700554173547	PRKCA/PRKCD/PRKCH	3
BP	GO:0042368	vitamin D biosynthetic process	3/232	10/18986	0.3	24.5508620689655	8.28527275985808	0.000202858994502622	0.00118662798973079	0.000592700554173547	CYP3A4/CYP2R1/TNF	3
BP	GO:0042420	dopamine catabolic process	3/232	10/18986	0.3	24.5508620689655	8.28527275985808	0.000202858994502622	0.00118662798973079	0.000592700554173547	MAOA/MAOB/SLC6A3	3
BP	GO:0042424	catecholamine catabolic process	3/232	10/18986	0.3	24.5508620689655	8.28527275985808	0.000202858994502622	0.00118662798973079	0.000592700554173547	MAOA/MAOB/SLC6A3	3
BP	GO:1901856	negative regulation of cellular respiration	3/232	10/18986	0.3	24.5508620689655	8.28527275985808	0.000202858994502622	0.00118662798973079	0.000592700554173547	SNCA/RHOA/TNF	3
BP	GO:0007249	canonical NF-kappaB signal transduction	13/232	327/18986	0.0397553516819572	3.25342718548982	4.57167722992425	0.000203653202653816	0.00118964630402693	0.000594208150970077	VEGFA/RHOA/EDNRA/ESR1/RORA/IKBKB/CHUK/XIAP/FLNA/BRD4/LTF/CLEC7A/TNF	13
BP	GO:0042113	B cell activation	12/232	284/18986	0.0422535211267606	3.4578678970374	4.64168878067712	0.000204639904850741	0.00119282725390508	0.00059579698148132	NTRK1/ITGB1/INHBA/PRKCD/ATM/MMP14/TP53/CDKN2A/EPHB2/TNFSF13/AHR/BCL2	12
BP	GO:0021953	central nervous system neuron differentiation	10/232	203/18986	0.0492610837438424	4.03134024120944	4.82950435336021	0.000205034619181534	0.00119282725390508	0.00059579698148132	NTRK2/NR4A2/INHBA/RORA/NRP2/EPHB2/EPHB3/EPHB1/NRP1/MAPT	10
BP	GO:0050728	negative regulation of inflammatory response	10/232	203/18986	0.0492610837438424	4.03134024120944	4.82950435336021	0.000205034619181534	0.00119282725390508	0.00059579698148132	APOA1/PRKCD/RORA/PLA2G10/IL12B/GRN/INS/HGF/AHR/ALOX5	10
BP	GO:0030307	positive regulation of cell growth	9/232	166/18986	0.0542168674698795	4.43690278354798	4.94668003217019	0.000209191856129983	0.00121535920762474	0.000607051310194131	VEGFA/PLAA/MMP14/F2/TGFBR1/NRP1/INS/MAPT/BCL2	9
BP	GO:0000077	DNA damage checkpoint signaling	8/232	131/18986	0.0610687022900763	4.99763095551461	5.10654797291939	0.000209893284995127	0.00121777976477498	0.000608260337434996	CDK2/ATM/ATR/CDK1/CDKN1B/TP53/MDM2/BRD4	8
BP	GO:0045786	negative regulation of cell cycle	15/232	419/18986	0.035799522673031	2.92969714426796	4.44250202321324	0.000210409848862554	0.00121912264733914	0.00060893108449882	CDK2/INHBA/ATM/ATR/CDK1/CDKN1B/TP53/CDKN2A/MDM2/BRD4/NR4A1/TNF/NPR2/BCL2/PTGS2	15
BP	GO:0022404	molting cycle process	7/232	99/18986	0.0707070707070707	5.78639846743295	5.31064529470717	0.000213224116883848	0.00123208962675045	0.000615407870778559	INHBA/PLA2G10/COL6A1/LAMA5/PDGFA/TNF/BCL2	7
BP	GO:0022405	hair cycle process	7/232	99/18986	0.0707070707070707	5.78639846743295	5.31064529470717	0.000213224116883848	0.00123208962675045	0.000615407870778559	INHBA/PLA2G10/COL6A1/LAMA5/PDGFA/TNF/BCL2	7
BP	GO:0035051	cardiocyte differentiation	9/232	167/18986	0.0538922155688623	4.41033450340698	4.9233337885068	0.000218797713097666	0.00126258977220731	0.000630642176113594	VEGFA/PDGFRB/PDGFRA/ITGB1/INHBA/EDNRA/CDK1/LMNA/PLEC	9
BP	GO:0045834	positive regulation of lipid metabolic process	8/232	132/18986	0.0606060606060606	4.95977011494253	5.0775887748629	0.000221119992672933	0.00127255597398312	0.000635620124861346	APOA1/PRKCD/F2/HTR2A/INS/TNF/MAPT/PTGS2	8
BP	GO:0098773	skin epidermis development	8/232	132/18986	0.0606060606060606	4.95977011494253	5.0775887748629	0.000221119992672933	0.00127255597398312	0.000635620124861346	INHBA/PLA2G10/COL6A1/LAMA5/PDGFA/TNF/BCL2/PLEC	8
BP	GO:0002483	antigen processing and presentation of endogenous peptide antigen	4/232	25/18986	0.16	13.0937931034483	6.72983253121446	0.00022460569909005	0.00128569473803086	0.000642182714653297	ERAP1/ERAP2/MICA/HLA-A	4
BP	GO:0010623	programmed cell death involved in cell development	4/232	25/18986	0.16	13.0937931034483	6.72983253121446	0.00022460569909005	0.00128569473803086	0.000642182714653297	NTRK1/DDB1/BCL2L1/BCL2	4
BP	GO:0050999	regulation of nitric-oxide synthase activity	4/232	25/18986	0.16	13.0937931034483	6.72983253121446	0.00022460569909005	0.00128569473803086	0.000642182714653297	ESR1/GLA/INS/NPR3	4
BP	GO:2000209	regulation of anoikis	4/232	25/18986	0.16	13.0937931034483	6.72983253121446	0.00022460569909005	0.00128569473803086	0.000642182714653297	NTRK2/ITGB1/BCL2L1/BCL2	4
BP	GO:0010595	positive regulation of endothelial cell migration	8/232	133/18986	0.0601503759398496	4.9224786103189	5.04892021756297	0.00023283454468437	0.00132569975109237	0.000662164540142389	VEGFA/KDR/PRKCA/NRP2/NRP1/GRN/PLG/PTGS2	8
BP	GO:0014902	myotube differentiation	8/232	133/18986	0.0601503759398496	4.9224786103189	5.04892021756297	0.00023283454468437	0.00132569975109237	0.000662164540142389	MYH9/ITGB1/MMP14/COL6A1/ADAMTS5/PPP3CA/BCL2/PLEC	8
BP	GO:0046632	alpha-beta T cell differentiation	8/232	133/18986	0.0601503759398496	4.9224786103189	5.04892021756297	0.00023283454468437	0.00132569975109237	0.000662164540142389	RHOA/RORA/IL18R1/BRD4/IL12B/BRAF/PRKCZ/BCL2	8
BP	GO:0050864	regulation of B cell activation	8/232	133/18986	0.0601503759398496	4.9224786103189	5.04892021756297	0.00023283454468437	0.00132569975109237	0.000662164540142389	INHBA/ATM/MMP14/CDKN2A/EPHB2/TNFSF13/AHR/BCL2	8
BP	GO:0048483	autonomic nervous system development	5/232	46/18986	0.108695652173913	8.89523988005997	5.96288722255348	0.000237777916589106	0.00135204570656252	0.000675323898039328	NTRK1/EDNRA/NRP2/NRP1/SLC6A4	5
BP	GO:0043271	negative regulation of monoatomic ion transport	8/232	134/18986	0.0597014925373134	4.88574369531652	5.02053699950554	0.000245052987369591	0.00139156251526211	0.000695061873730203	CRBN/MMP9/MAOB/EPHB2/HTR2A/PPP3CA/BCL2/PTGS2	8
BP	GO:0046626	regulation of insulin receptor signaling pathway	6/232	72/18986	0.0833333333333333	6.81968390804598	5.50270575010362	0.000248785470951916	0.00140715168490792	0.000702848399556442	PRKCD/PRKCQ/AHSG/IGF2/INS/PRKCZ	6
BP	GO:0048002	antigen processing and presentation of peptide antigen	6/232	72/18986	0.0833333333333333	6.81968390804598	5.50270575010362	0.000248785470951916	0.00140715168490792	0.000702848399556442	IKBKB/ERAP1/LNPEP/ERAP2/MICA/HLA-A	6
BP	GO:0050918	positive chemotaxis	6/232	72/18986	0.0833333333333333	6.81968390804598	5.50270575010362	0.000248785470951916	0.00140715168490792	0.000702848399556442	VEGFA/KDR/CXCL8/NTRK3/NRP1/HGF	6
BP	GO:0050764	regulation of phagocytosis	7/232	102/18986	0.0686274509803922	5.61621027721433	5.19925371604548	0.000256454623038772	0.00144861290371703	0.000723557575117387	APOA1/FCGR2A/PLA2G5/AHSG/HSPA8/CLEC7A/ALOX15	7
BP	GO:0002244	hematopoietic progenitor cell differentiation	8/232	135/18986	0.0592592592592593	4.84955300127714	4.99243395539833	0.000257791705601453	0.0014542445028388	0.000726370463359739	VEGFA/KDR/PDGFRA/INHBA/TP53/BRAF/LIPA/BCL2	8
BP	GO:0050927	positive regulation of positive chemotaxis	4/232	26/18986	0.153846153846154	12.5901856763926	6.57749063344825	0.00026291223705919	0.00147648533038694	0.000737479379487741	VEGFA/KDR/CXCL8/NTRK3	4
BP	GO:0051882	mitochondrial depolarization	4/232	26/18986	0.153846153846154	12.5901856763926	6.57749063344825	0.00026291223705919	0.00147648533038694	0.000737479379487741	KDR/CDKN2A/COL6A1/BCL2	4
BP	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	4/232	26/18986	0.153846153846154	12.5901856763926	6.57749063344825	0.00026291223705919	0.00147648533038694	0.000737479379487741	RHOA/ITGB2/TNF/ALOX5	4
BP	GO:0006775	fat-soluble vitamin metabolic process	5/232	47/18986	0.106382978723404	8.70597945707997	5.88302360850965	0.000263460782760813	0.00147648533038694	0.000737479379487741	CYP3A4/CYP1A1/CYP2R1/LIPA/TNF	5
BP	GO:2000378	negative regulation of reactive oxygen species metabolic process	5/232	47/18986	0.106382978723404	8.70597945707997	5.88302360850965	0.000263460782760813	0.00147648533038694	0.000737479379487741	RHOA/MMP3/TP53/INS/BCL2	5
BP	GO:0050766	positive regulation of phagocytosis	6/232	73/18986	0.0821917808219178	6.7262635805385	5.45198799534517	0.0002683318789199	0.0015018155945831	0.000750131416820717	APOA1/FCGR2A/PLA2G5/AHSG/HSPA8/CLEC7A	6
BP	GO:0048469	cell maturation	10/232	210/18986	0.0476190476190476	3.89696223316913	4.69519117152364	0.000269301638788348	0.00150527295092676	0.000751858307673281	VEGFA/KDR/NR4A2/PDE3A/EDNRA/PLA2G10/FGG/CLEC7A/NPR2/BCL2	10
BP	GO:0021782	glial cell development	8/232	136/18986	0.0588235294117647	4.81389452332657	4.96460605168248	0.000271067424606811	0.00151119205686926	0.000754814800696109	NTRK2/COL6A1/LAMB2/RAF1/GRN/TNF/MAPT/PLEC	8
BP	GO:0038127	ERBB signaling pathway	8/232	136/18986	0.0588235294117647	4.81389452332657	4.96460605168248	0.000271067424606811	0.00151119205686926	0.000754814800696109	ITGA1/PDE6H/SHC1/MMP9/PLAUR/RAF1/BRAF/NPR2	8
BP	GO:0003205	cardiac chamber development	9/232	172/18986	0.0523255813953488	4.28212710505213	4.809294660618	0.00027249997390902	0.00151720037556636	0.0007578158539767	EDNRA/NRP2/ADAMTS1/TP53/MYH7/MDM2/COL11A1/TGFBR1/NRP1	9
BP	GO:0007343	egg activation	3/232	11/18986	0.272727272727273	22.3189655172414	7.86636175660475	0.000276417551104208	0.00152314619654844	0.000760785690708678	MYH9/PLAT/NPR2	3
BP	GO:0021562	vestibulocochlear nerve development	3/232	11/18986	0.272727272727273	22.3189655172414	7.86636175660475	0.000276417551104208	0.00152314619654844	0.000760785690708678	NRP2/NRP1/NPR2	3
BP	GO:0021604	cranial nerve structural organization	3/232	11/18986	0.272727272727273	22.3189655172414	7.86636175660475	0.000276417551104208	0.00152314619654844	0.000760785690708678	KCNA2/NRP2/NRP1	3
BP	GO:0032754	positive regulation of interleukin-5 production	3/232	11/18986	0.272727272727273	22.3189655172414	7.86636175660475	0.000276417551104208	0.00152314619654844	0.000760785690708678	PDE4D/IL17RA/PRKCZ	3
BP	GO:0032836	glomerular basement membrane development	3/232	11/18986	0.272727272727273	22.3189655172414	7.86636175660475	0.000276417551104208	0.00152314619654844	0.000760785690708678	COL4A3/COL4A4/LAMB2	3
BP	GO:0060346	bone trabecula formation	3/232	11/18986	0.272727272727273	22.3189655172414	7.86636175660475	0.000276417551104208	0.00152314619654844	0.000760785690708678	VEGFA/MMP2/COL1A1	3
BP	GO:0060736	prostate gland growth	3/232	11/18986	0.272727272727273	22.3189655172414	7.86636175660475	0.000276417551104208	0.00152314619654844	0.000760785690708678	PSAP/ESR1/AR	3
BP	GO:0110011	regulation of basement membrane organization	3/232	11/18986	0.272727272727273	22.3189655172414	7.86636175660475	0.000276417551104208	0.00152314619654844	0.000760785690708678	LAMA1/LAMB1/LAMB2	3
BP	GO:1901987	regulation of cell cycle phase transition	16/232	479/18986	0.0334029227557411	2.73356849758837	4.27408434158998	0.000283369103009443	0.00155944180755261	0.000778914732786235	DDB1/CDC7/CDK2/INHBA/ATM/ATR/CDK1/CDKN1B/ADAMTS1/SMARCA4/CYP1A1/TP53/CDKN2A/MDM2/BRD4/BCL2	16
BP	GO:0048738	cardiac muscle tissue development	11/232	252/18986	0.0436507936507936	3.57221538040504	4.57187850264232	0.000284516380092067	0.00156374298364226	0.000781063097289681	VEGFA/PDGFRB/PDGFRA/ITGB1/EDNRA/CDK1/LMNA/MYH7/COL11A1/TGFBR1/PLEC	11
BP	GO:0048565	digestive tract development	8/232	137/18986	0.0583941605839416	4.77875660709791	4.93704838222407	0.000284897211680757	0.00156382602971363	0.000781104577393764	PDGFRA/CXCL8/CYP1A1/EPHB3/COL3A1/TNF/NPR2/BCL2	8
BP	GO:0006953	acute-phase response	5/232	48/18986	0.104166666666667	8.52460488505747	5.8054996084824	0.000291196286360292	0.0015922702307885	0.000795311973381387	AHSG/F2/INS/TNF/PTGS2	5
BP	GO:0048806	genitalia development	5/232	48/18986	0.104166666666667	8.52460488505747	5.8054996084824	0.000291196286360292	0.0015922702307885	0.000795311973381387	PDGFRA/ESR1/NPR2/AR/SRD5A1	5
BP	GO:0120163	negative regulation of cold-induced thermogenesis	5/232	48/18986	0.104166666666667	8.52460488505747	5.8054996084824	0.000291196286360292	0.0015922702307885	0.000795311973381387	IL18R1/LNPEP/LAMA4/ADAMTS5/NPR3	5
BP	GO:0060047	heart contraction	11/232	253/18986	0.0434782608695652	3.55809595202399	4.55591656328377	0.000294306979794144	0.0016072243238822	0.000802781289241539	PDE5A/PDE4D/PDE4B/EDNRA/THRA/FLNA/MYH7/MDM2/THRB/TNF/ADORA3	11
BP	GO:1903706	regulation of hemopoiesis	15/232	433/18986	0.0346420323325635	2.8349725252847	4.29604457877126	0.000298830790180361	0.00162984752399391	0.000814081193979529	PRKCA/RHOA/INHBA/HSPA1A/SMARCA4/MMP14/CDKN2A/BRD4/LTF/IL12B/BRAF/PF4/TNF/PPP3CA/PRKCZ	15
BP	GO:0043401	steroid hormone receptor signaling pathway	8/232	138/18986	0.0579710144927536	4.74412793603198	4.90975616417691	0.000299298477792632	0.00163031884209082	0.000814316609374791	PDE3A/NR4A3/SKP2/RHOA/ESR1/ESR2/SMARCA4/AR	8
BP	GO:0090257	regulation of muscle system process	11/232	254/18986	0.0433070866141732	3.54408770024437	4.5400349841526	0.000304380228355148	0.00165589040260383	0.000827089170125345	PDE5A/PDE4D/PDE4B/PRKCA/NR4A3/RHOA/LMNA/MYH7/NR4A1/PPP3CA/PTGS2	11
BP	GO:0050926	regulation of positive chemotaxis	4/232	27/18986	0.148148148148148	12.1238825031928	6.43328659463188	0.000305694547186201	0.00165881964945202	0.000828552279242321	VEGFA/KDR/CXCL8/NTRK3	4
BP	GO:0060343	trabecula formation	4/232	27/18986	0.148148148148148	12.1238825031928	6.43328659463188	0.000305694547186201	0.00165881964945202	0.000828552279242321	VEGFA/MMP2/ADAMTS1/COL1A1	4
BP	GO:0051962	positive regulation of nervous system development	12/232	297/18986	0.0404040404040404	3.30651340996169	4.4559828832164	0.000308016404058417	0.00166930056242559	0.000833787317503207	VEGFA/NTRK1/NTRK2/ITGB1/PRKCH/EPHB2/EPHB3/EPHB1/BRAF/NRP1/TNF/MAPT	12
BP	GO:0007338	single fertilization	9/232	175/18986	0.0514285714285714	4.20871921182266	4.74293458160107	0.000309662987646889	0.00167609991794696	0.000837183480260544	MYH9/CDK1/PLA2G10/ALDOA/COL6A1/PLAT/B4GALT1/NPR2/AR	9
BP	GO:0046635	positive regulation of alpha-beta T cell activation	6/232	75/18986	0.08	6.54689655172414	5.35335184743925	0.000311034351073459	0.00168139429227574	0.00083982793043855	RHOA/PRKCQ/BRD4/IL12B/HLA-A/PRKCZ	6
BP	GO:0031400	negative regulation of protein modification process	13/232	342/18986	0.0380116959064327	3.11073301068764	4.38105944057938	0.000314103837429017	0.00169470324660489	0.000846475527389425	SNCA/PDE4D/PLAA/PRKCD/PRKCH/HSPA1A/CDKN1B/CDKN2A/EPHB2/NTRK3/PPIA/PRKCZ/MAPT	13
BP	GO:0007266	Rho protein signal transduction	8/232	139/18986	0.0575539568345324	4.709997519226	4.88272473400876	0.000314288979082712	0.00169470324660489	0.000846475527389425	RHOA/APOA1/ITGB1/ABCA1/COL1A2/COL3A1/RAF1/NRP1	8
BP	GO:1901617	organic hydroxy compound biosynthetic process	11/232	255/18986	0.0431372549019608	3.53018931710615	4.52423300190446	0.000314742600198156	0.00169501178645758	0.00084662963781262	NR4A2/SNCA/HMGCR/APOA1/INHBA/CYP3A4/CYP2R1/LIPA/TNF/ALOX15/SLC6A3	11
BP	GO:0006693	prostaglandin metabolic process	5/232	49/18986	0.102040816326531	8.35063335679099	5.730196945649	0.00032109052542844	0.00172268894194731	0.000860453907540519	PLAA/PLA2G10/CYP2S1/PTGS1/PTGS2	5
BP	GO:0030850	prostate gland development	5/232	49/18986	0.102040816326531	8.35063335679099	5.730196945649	0.00032109052542844	0.00172268894194731	0.000860453907540519	MMP2/PSAP/ESR1/CDKN1B/AR	5
BP	GO:0042269	regulation of natural killer cell mediated cytotoxicity	5/232	49/18986	0.102040816326531	8.35063335679099	5.730196945649	0.00032109052542844	0.00172268894194731	0.000860453907540519	IL12B/KLRK1/MICA/HLA-A/HAVCR2	5
BP	GO:0050905	neuromuscular process	9/232	176/18986	0.0511363636363636	4.18480603448276	4.72114415067448	0.000322944712837994	0.00173046565425471	0.000864338243435285	HEXA/PDE8B/EDNRA/CHUK/MYH7/NR4A1/TNF/NPR2/SLC6A3	9
BP	GO:0009408	response to heat	7/232	106/18986	0.0660377358490566	5.40427781392323	5.05741952253558	0.000324786500244393	0.00173815653948063	0.000868179710158584	ATM/ATR/HSPA1A/HSPA8/MICA/MAPT/PTGS2	7
BP	GO:0031570	DNA integrity checkpoint signaling	8/232	140/18986	0.0571428571428571	4.67635467980296	4.85594954368325	0.000329886818248497	0.00176324504353822	0.000880710992402897	CDK2/ATM/ATR/CDK1/CDKN1B/TP53/MDM2/BRD4	8
BP	GO:0050795	regulation of behavior	6/232	76/18986	0.0789473684210526	6.46075317604356	5.30537291747679	0.000334291871695328	0.00178233421866487	0.000890245711602337	NR4A3/KCNA2/EPHB2/GLA/HTR1A/INS	6
BP	GO:2000242	negative regulation of reproductive process	6/232	76/18986	0.0789473684210526	6.46075317604356	5.30537291747679	0.000334291871695328	0.00178233421866487	0.000890245711602337	DDB1/MYH9/CDKN1B/PLAT/NPR2/BCL2L1	6
BP	GO:0009566	fertilization	10/232	216/18986	0.0462962962962963	3.78871328224776	4.58459463429286	0.000337070649855876	0.00179491170458745	0.000896527952490754	MYH9/CDK1/PLA2G10/ALDOA/COL6A1/PLAT/B4GALT1/NPR2/AR/BCL2L1	10
BP	GO:0051235	maintenance of location	13/232	345/18986	0.0376811594202899	3.08368315842079	4.3441915166362	0.000341452970353764	0.00181598619556305	0.000907054303283304	HEXA/SNCA/PDE4D/APOA1/HSPA5/PLA2G10/FLNA/GLA/ABCA1/F2/HTR2A/LIPA/TNF	13
BP	GO:0045639	positive regulation of myeloid cell differentiation	7/232	107/18986	0.0654205607476635	5.35377054463422	5.02308202156438	0.00034396559579302	0.00182707687901982	0.000912593911558074	PRKCA/INHBA/HSPA1A/IL12B/PF4/TNF/PPP3CA	7
BP	GO:0000086	G2/M transition of mitotic cell cycle	8/232	141/18986	0.0567375886524823	4.64318904377598	4.82942615699048	0.000346110445819629	0.00183618891603565	0.000917145219495922	CDC7/CDK2/CCNA2/SKP2/ATM/ATR/CDK1/BRD4	8
BP	GO:0002726	positive regulation of T cell cytokine production	4/232	28/18986	0.142857142857143	11.6908866995074	6.29649438682258	0.000353245835880892	0.00186482077991224	0.000931446349870005	IL1R1/IL18R1/HLA-A/PRKCZ	4
BP	GO:0002347	response to tumor cell	5/232	50/18986	0.1	8.18362068965517	5.65700561295886	0.000353251831554938	0.00186482077991224	0.000931446349870005	IL12B/MICA/HLA-A/HAVCR2/AHR	5
BP	GO:0006692	prostanoid metabolic process	5/232	50/18986	0.1	8.18362068965517	5.65700561295886	0.000353251831554938	0.00186482077991224	0.000931446349870005	PLAA/PLA2G10/CYP2S1/PTGS1/PTGS2	5
BP	GO:0071827	plasma lipoprotein particle organization	5/232	50/18986	0.1	8.18362068965517	5.65700561295886	0.000353251831554938	0.00186482077991224	0.000931446349870005	APOA1/PLA2G2A/PLA2G5/PLA2G10/ABCA1	5
BP	GO:0043406	positive regulation of MAP kinase activity	6/232	77/18986	0.0779220779220779	6.37684729064039	5.25824867590822	0.000358889712589351	0.00188991676235476	0.000943981367440748	PDE5A/PDGFRB/NTRK3/PDGFA/FLT1/TNF	6
BP	GO:1900076	regulation of cellular response to insulin stimulus	6/232	77/18986	0.0779220779220779	6.37684729064039	5.25824867590822	0.000358889712589351	0.00188991676235476	0.000943981367440748	PRKCD/PRKCQ/AHSG/IGF2/INS/PRKCZ	6
BP	GO:0045216	cell-cell junction organization	10/232	218/18986	0.0458715596330275	3.75395444479595	4.54860619755034	0.000362602431609731	0.00190690509562761	0.000952466751767127	VEGFA/PRKCA/RHOA/PRKCH/IKBKB/EPHB2/FLNA/TGFBR1/TNF/PLEC	10
BP	GO:0001553	luteinization	3/232	12/18986	0.25	20.4590517241379	7.49954965076802	0.000365237435294437	0.00190690509562761	0.000952466751767127	MMP2/PDGFRA/INHBA	3
BP	GO:0019336	phenol-containing compound catabolic process	3/232	12/18986	0.25	20.4590517241379	7.49954965076802	0.000365237435294437	0.00190690509562761	0.000952466751767127	MAOA/MAOB/SLC6A3	3
BP	GO:0034350	regulation of glial cell apoptotic process	3/232	12/18986	0.25	20.4590517241379	7.49954965076802	0.000365237435294437	0.00190690509562761	0.000952466751767127	PRKCA/PRKCD/PRKCH	3
BP	GO:0042416	dopamine biosynthetic process	3/232	12/18986	0.25	20.4590517241379	7.49954965076802	0.000365237435294437	0.00190690509562761	0.000952466751767127	NR4A2/SNCA/SLC6A3	3
BP	GO:0051081	nuclear membrane disassembly	3/232	12/18986	0.25	20.4590517241379	7.49954965076802	0.000365237435294437	0.00190690509562761	0.000952466751767127	PRKCA/ATR/CDK1	3
BP	GO:0071236	cellular response to antibiotic	3/232	12/18986	0.25	20.4590517241379	7.49954965076802	0.000365237435294437	0.00190690509562761	0.000952466751767127	CDKN1B/TP53/MDM2	3
BP	GO:0050870	positive regulation of T cell activation	11/232	260/18986	0.0423076923076923	3.46230106100796	4.44639103749507	0.000371125252570906	0.00193528241462585	0.000966640741291872	RHOA/PRKCQ/SMARCA4/BRD4/IGF2/IL12B/KLRK1/HLA-A/PPP3CA/HAVCR2/PRKCZ	11
BP	GO:0032970	regulation of actin filament-based process	14/232	395/18986	0.0354430379746835	2.90052378873854	4.24544109756916	0.000377372328224057	0.00196546172409996	0.000981714794495303	PDE4D/PDE4B/RHOA/APOA1/PDGFRB/PDGFRA/MYH9/PRKCD/FLNA/BRAF/TGFBR1/PDGFA/NRP1/ALOX15	14
BP	GO:0141193	nuclear receptor-mediated signaling pathway	9/232	180/18986	0.05	4.09181034482759	4.63557081523918	0.000380873962444255	0.00198128596522096	0.000989618734536295	SKP2/RHOA/ESR1/THRA/ESR2/SMARCA4/THRB/AR/ALOX15	9
BP	GO:0031343	positive regulation of cell killing	6/232	78/18986	0.0769230769230769	6.29509283819629	5.21195216126861	0.000384881327788442	0.00199570395397134	0.000996820275369957	IL12B/HSPA8/KLRK1/MICA/HLA-A/CLEC7A	6
BP	GO:0043536	positive regulation of blood vessel endothelial cell migration	6/232	78/18986	0.0769230769230769	6.29509283819629	5.21195216126861	0.000384881327788442	0.00199570395397134	0.000996820275369957	VEGFA/KDR/PRKCA/NRP1/PLG/PTGS2	6
BP	GO:0048144	fibroblast proliferation	7/232	109/18986	0.0642201834862385	5.25553622271433	4.95568153774362	0.000385045781577725	0.00199570395397134	0.000996820275369957	CCNA2/PDGFRA/ESR1/CDK1/TP53/COL3A1/PDGFA	7
BP	GO:0051496	positive regulation of stress fiber assembly	5/232	51/18986	0.0980392156862745	8.02315753887762	5.58582314234308	0.000387790705997032	0.00200507020416361	0.00100149855847766	RHOA/APOA1/BRAF/TGFBR1/NRP1	5
BP	GO:1990090	cellular response to nerve growth factor stimulus	5/232	51/18986	0.0980392156862745	8.02315753887762	5.58582314234308	0.000387790705997032	0.00200507020416361	0.00100149855847766	NTRK1/NTRK2/NTRK3/BRAF/MAPT	5
BP	GO:0021700	developmental maturation	13/232	350/18986	0.0371428571428571	3.03963054187192	4.28362569711025	0.000391548219615455	0.00202205336603344	0.00100998135977594	VEGFA/KDR/MMP2/NR4A2/PDE3A/RHOA/EDNRA/PLA2G10/LTF/FGG/CLEC7A/NPR2/BCL2	13
BP	GO:0003015	heart process	11/232	262/18986	0.0419847328244275	3.43587128191629	4.41578583532203	0.000395940584390555	0.00204227013130761	0.00102007929112874	PDE5A/PDE4D/PDE4B/EDNRA/THRA/FLNA/MYH7/MDM2/THRB/TNF/ADORA3	11
BP	GO:0021952	central nervous system projection neuron axonogenesis	4/232	29/18986	0.137931034482759	11.2877526753864	6.16647600943178	0.000405862774045348	0.00207681068570615	0.00103733171219974	NR4A2/EPHB2/EPHB3/EPHB1	4
BP	GO:0060384	innervation	4/232	29/18986	0.137931034482759	11.2877526753864	6.16647600943178	0.000405862774045348	0.00207681068570615	0.00103733171219974	NTRK1/EDNRA/NRP1/NPR2	4
BP	GO:0060479	lung cell differentiation	4/232	29/18986	0.137931034482759	11.2877526753864	6.16647600943178	0.000405862774045348	0.00207681068570615	0.00103733171219974	THRA/LTA4H/COL6A1/THRB	4
BP	GO:0060487	lung epithelial cell differentiation	4/232	29/18986	0.137931034482759	11.2877526753864	6.16647600943178	0.000405862774045348	0.00207681068570615	0.00103733171219974	THRA/LTA4H/COL6A1/THRB	4
BP	GO:1902914	regulation of protein polyubiquitination	4/232	29/18986	0.137931034482759	11.2877526753864	6.16647600943178	0.000405862774045348	0.00207681068570615	0.00103733171219974	PLAA/SKP2/XIAP/PPIA	4
BP	GO:0010586	miRNA metabolic process	7/232	110/18986	0.0636363636363636	5.20775862068965	4.92259962209535	0.000407008268152888	0.00207681068570615	0.00103733171219974	VEGFA/EGR1/ESR1/SMARCA4/TP53/TNF/AR	7
BP	GO:0048675	axon extension	7/232	110/18986	0.0636363636363636	5.20775862068965	4.92259962209535	0.000407008268152888	0.00207681068570615	0.00103733171219974	VEGFA/ITGB1/EDNRA/NRP2/LAMB2/NRP1/MAPT	7
BP	GO:0060291	long-term synaptic potentiation	7/232	110/18986	0.0636363636363636	5.20775862068965	4.92259962209535	0.000407008268152888	0.00207681068570615	0.00103733171219974	NTRK2/SNCA/HMGCR/EPHB2/BRAF/INS/PRKCZ	7
BP	GO:1901796	regulation of signal transduction by p53 class mediator	7/232	110/18986	0.0636363636363636	5.20775862068965	4.92259962209535	0.000407008268152888	0.00207681068570615	0.00103733171219974	ATM/ATR/TP53/CDKN2A/MDM2/BCL2/DYRK1A	7
BP	GO:0001937	negative regulation of endothelial cell proliferation	6/232	79/18986	0.0759493670886076	6.21540811872545	5.16645760040584	0.000412321244285086	0.00209687591934576	0.00104735395607123	IL12B/COL4A3/TGFBR1/FLT1/TNF/ALOX5	6
BP	GO:0042267	natural killer cell mediated cytotoxicity	6/232	79/18986	0.0759493670886076	6.21540811872545	5.16645760040584	0.000412321244285086	0.00209687591934576	0.00104735395607123	IL12B/KLRK1/MICA/HLA-A/FCGR3A/HAVCR2	6
BP	GO:0031214	biomineral tissue development	9/232	182/18986	0.0494505494505494	4.04684539598333	4.59370738687518	0.000412902133790723	0.00209687591934576	0.00104735395607123	MMP13/AHSG/LTF/COL1A2/COL1A1/COL6A1/ALOX5/ALOX15/PTGS2	9
BP	GO:0042129	regulation of T cell proliferation	9/232	182/18986	0.0494505494505494	4.04684539598333	4.59370738687518	0.000412902133790723	0.00209687591934576	0.00104735395607123	PDE5A/PRKCQ/PLA2G5/CDKN2A/IGF2/IL12B/HLA-A/PPP3CA/HAVCR2	9
BP	GO:0030100	regulation of endocytosis	12/232	307/18986	0.0390879478827362	3.19880939009323	4.319985578495	0.000415044208704471	0.00210525389848199	0.00105153861454876	VEGFA/SNCA/APOA1/FCGR2A/PLA2G5/AHSG/MDM2/AP2A1/HSPA8/CLEC7A/PPP3CA/ALOX15	12
BP	GO:0001974	blood vessel remodeling	5/232	52/18986	0.0961538461538462	7.86886604774536	5.51655395142772	0.000424819754327206	0.00214719771808881	0.00107248884102265	EDNRA/FLNA/MDM2/NPR2/NPR3	5
BP	GO:0042572	retinol metabolic process	5/232	52/18986	0.0961538461538462	7.86886604774536	5.51655395142772	0.000424819754327206	0.00214719771808881	0.00107248884102265	CYP3A4/CYP1A1/CYP1A2/CYP2D6/CYP1B1	5
BP	GO:0060688	regulation of morphogenesis of a branching structure	5/232	52/18986	0.0961538461538462	7.86886604774536	5.51655395142772	0.000424819754327206	0.00214719771808881	0.00107248884102265	VEGFA/ESR1/PDGFA/TNF/HGF	5
BP	GO:0009755	hormone-mediated signaling pathway	10/232	223/18986	0.0448430493273543	3.66978506262564	4.46046286905017	0.000433569553553133	0.0021888351959778	0.00109328605500442	PDE3A/NR4A3/SKP2/RHOA/ESR1/THRA/ESR2/SMARCA4/THRB/AR	10
BP	GO:0043467	regulation of generation of precursor metabolites and energy	8/232	146/18986	0.0547945205479452	4.484175720359	4.7004384051945	0.00043728566350022	0.00220239516740511	0.00110005903073826	SNCA/RHOA/CDK1/TP53/IGF2/HTR2A/INS/TNF	8
BP	GO:0050770	regulation of axonogenesis	8/232	146/18986	0.0547945205479452	4.484175720359	4.7004384051945	0.00043728566350022	0.00220239516740511	0.00110005903073826	VEGFA/NTRK2/EPHB2/EPHB3/GLA/BRAF/NRP1/MAPT	8
BP	GO:0072330	monocarboxylic acid biosynthetic process	10/232	224/18986	0.0446428571428571	3.65340209359606	4.44313846972515	0.000449064881153706	0.00225640591282403	0.00112703648198512	PLA2G10/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2D6/ALOX5/PTGS1/ALOX15/PTGS2	10
BP	GO:1901654	response to ketone	10/232	224/18986	0.0446428571428571	3.65340209359606	4.44313846972515	0.000449064881153706	0.00225640591282403	0.00112703648198512	INHBA/MAOB/CYP1A1/CYP1B1/HSPA8/LIPA/AHR/AR/BCL2L1/SRD5A1	10
BP	GO:0009117	nucleotide metabolic process	16/232	500/18986	0.032	2.61875862068966	4.07988535374576	0.000453965601459248	0.0022783531829105	0.00113799877114012	PDE5A/PDE4A/PDE4D/PDE4B/PDE8B/RORA/HSPA1A/TP53/ALDOA/MYH7/COL6A1/HTR2A/HSPA8/INS/LIPA/NPR2	16
BP	GO:0030099	myeloid cell differentiation	15/232	451/18986	0.0332594235033259	2.72182506307822	4.11607555655357	0.000458214076671839	0.00229697935738427	0.00114730222936652	VEGFA/PRKCA/MYH9/INHBA/MMP9/THRA/HSPA1A/PLA2G10/FLNA/LTF/IL12B/PF4/LIPA/TNF/PPP3CA	15
BP	GO:0001963	synaptic transmission, dopaminergic	4/232	30/18986	0.133333333333333	10.9114942528736	6.04266820240947	0.000463845042441395	0.00230394858237077	0.00115078323904049	SNCA/PTGS2/SLC6A4/SLC6A3	4
BP	GO:0072012	glomerulus vasculature development	4/232	30/18986	0.133333333333333	10.9114942528736	6.04266820240947	0.000463845042441395	0.00230394858237077	0.00115078323904049	PDGFRB/PDGFRA/EGR1/EDNRA	4
BP	GO:0090330	regulation of platelet aggregation	4/232	30/18986	0.133333333333333	10.9114942528736	6.04266820240947	0.000463845042441395	0.00230394858237077	0.00115078323904049	PRKCA/PRKCD/PRKCQ/HTR2A	4
BP	GO:0010001	glial cell differentiation	11/232	267/18986	0.0411985018726592	3.37152912307891	4.34055344634949	0.000464143837978117	0.00230394858237077	0.00115078323904049	NTRK2/RHOA/CDK1/F2/COL6A1/LAMB2/RAF1/GRN/TNF/MAPT/PLEC	11
BP	GO:0014075	response to amine	5/232	53/18986	0.0943396226415094	7.72039687703318	5.44910875821419	0.000464453619738915	0.00230394858237077	0.00115078323904049	NR4A2/EDNRA/CDK1/NR4A1/PPP3CA	5
BP	GO:0035094	response to nicotine	5/232	53/18986	0.0943396226415094	7.72039687703318	5.44910875821419	0.000464453619738915	0.00230394858237077	0.00115078323904049	NTRK1/MMP2/TNF/BCL2/SLC6A3	5
BP	GO:0048009	insulin-like growth factor receptor signaling pathway	5/232	53/18986	0.0943396226415094	7.72039687703318	5.44910875821419	0.000464453619738915	0.00230394858237077	0.00115078323904049	SHC1/IGF2/COL6A1/RAF1/AR	5
BP	GO:0071825	protein-lipid complex organization	5/232	53/18986	0.0943396226415094	7.72039687703318	5.44910875821419	0.000464453619738915	0.00230394858237077	0.00115078323904049	APOA1/PLA2G2A/PLA2G5/PLA2G10/ABCA1	5
BP	GO:1990089	response to nerve growth factor	5/232	53/18986	0.0943396226415094	7.72039687703318	5.44910875821419	0.000464453619738915	0.00230394858237077	0.00115078323904049	NTRK1/NTRK2/NTRK3/BRAF/MAPT	5
BP	GO:0009415	response to water	3/232	13/18986	0.230769230769231	18.8852785145889	7.17466648464199	0.000470534920009051	0.00231531336934258	0.00115645975737189	NTRK1/COL18A1/PLEC	3
BP	GO:0030397	membrane disassembly	3/232	13/18986	0.230769230769231	18.8852785145889	7.17466648464199	0.000470534920009051	0.00231531336934258	0.00115645975737189	PRKCA/ATR/CDK1	3
BP	GO:0031650	regulation of heat generation	3/232	13/18986	0.230769230769231	18.8852785145889	7.17466648464199	0.000470534920009051	0.00231531336934258	0.00115645975737189	HTR2A/TNF/PTGS2	3
BP	GO:0042362	fat-soluble vitamin biosynthetic process	3/232	13/18986	0.230769230769231	18.8852785145889	7.17466648464199	0.000470534920009051	0.00231531336934258	0.00115645975737189	CYP3A4/CYP2R1/TNF	3
BP	GO:0048680	positive regulation of axon regeneration	3/232	13/18986	0.230769230769231	18.8852785145889	7.17466648464199	0.000470534920009051	0.00231531336934258	0.00115645975737189	FLNA/BRAF/GRN	3
BP	GO:0070572	positive regulation of neuron projection regeneration	3/232	13/18986	0.230769230769231	18.8852785145889	7.17466648464199	0.000470534920009051	0.00231531336934258	0.00115645975737189	FLNA/BRAF/GRN	3
BP	GO:0071679	commissural neuron axon guidance	3/232	13/18986	0.230769230769231	18.8852785145889	7.17466648464199	0.000470534920009051	0.00231531336934258	0.00115645975737189	VEGFA/EPHB2/NRP1	3
BP	GO:0050807	regulation of synapse organization	12/232	312/18986	0.0384615384615385	3.14754641909814	4.25405907926523	0.000479389651338148	0.00235617258519761	0.001176868242668	NTRK1/NTRK2/SNCA/RHOA/ITGB1/NRP2/EPHB2/EPHB3/EPHB1/HSPA8/INS/TNF	12
BP	GO:0007173	epidermal growth factor receptor signaling pathway	7/232	114/18986	0.0614035087719298	5.02503024803388	4.79418675246626	0.000505084513671654	0.00247961122900114	0.00123852375157385	ITGA1/PDE6H/SHC1/MMP9/PLAUR/BRAF/NPR2	7
BP	GO:0032640	tumor necrosis factor production	9/232	188/18986	0.0478723404255319	3.91769075568599	4.47161803130219	0.00052256028624923	0.0025595278167259	0.00127844073165695	FCGR2A/MMP8/EPHB2/LTF/IL12B/PF4/CLEC7A/FCGR3A/HAVCR2	9
BP	GO:0032680	regulation of tumor necrosis factor production	9/232	188/18986	0.0478723404255319	3.91769075568599	4.47161803130219	0.00052256028624923	0.0025595278167259	0.00127844073165695	FCGR2A/MMP8/EPHB2/LTF/IL12B/PF4/CLEC7A/FCGR3A/HAVCR2	9
BP	GO:0002825	regulation of T-helper 1 type immune response	4/232	31/18986	0.129032258064516	10.559510567297	5.92457153303644	0.000527494893706384	0.00256898424315318	0.00128316405626454	IL1R1/IL18R1/IL12B/HAVCR2	4
BP	GO:0008209	androgen metabolic process	4/232	31/18986	0.129032258064516	10.559510567297	5.92457153303644	0.000527494893706384	0.00256898424315318	0.00128316405626454	INHBA/ESR1/CYP3A4/SRD5A1	4
BP	GO:0030878	thyroid gland development	4/232	31/18986	0.129032258064516	10.559510567297	5.92457153303644	0.000527494893706384	0.00256898424315318	0.00128316405626454	EDNRA/THRA/RAF1/BRAF	4
BP	GO:0033688	regulation of osteoblast proliferation	4/232	31/18986	0.129032258064516	10.559510567297	5.92457153303644	0.000527494893706384	0.00256898424315318	0.00128316405626454	RHOA/LTF/NPR3/BCL2	4
BP	GO:0050951	sensory perception of temperature stimulus	4/232	31/18986	0.129032258064516	10.559510567297	5.92457153303644	0.000527494893706384	0.00256898424315318	0.00128316405626454	NTRK1/EPHB1/HTR2A/TRPA1	4
BP	GO:0019233	sensory perception of pain	6/232	83/18986	0.072289156626506	5.91587037806398	4.99202140923502	0.000537691394011343	0.00260676689432257	0.00130203584968256	NTRK1/KCNA2/EPHB1/HTR2A/TNF/TRPA1	6
BP	GO:0048844	artery morphogenesis	6/232	83/18986	0.072289156626506	5.91587037806398	4.99202140923502	0.000537691394011343	0.00260676689432257	0.00130203584968256	VEGFA/PDGFRB/EDNRA/COL3A1/TGFBR1/NRP1	6
BP	GO:0051952	regulation of amine transport	6/232	83/18986	0.072289156626506	5.91587037806398	4.99202140923502	0.000537691394011343	0.00260676689432257	0.00130203584968256	SNCA/ITGB1/KCNA2/HTR2A/TNF/ADORA3	6
BP	GO:0120193	tight junction organization	6/232	83/18986	0.072289156626506	5.91587037806398	4.99202140923502	0.000537691394011343	0.00260676689432257	0.00130203584968256	PRKCH/IKBKB/EPHB2/TGFBR1/TNF/PLEC	6
BP	GO:0001764	neuron migration	9/232	189/18986	0.0476190476190476	3.89696223316913	4.45176060750721	0.000542968244486742	0.00262936830512492	0.0013133248710301	VEGFA/NTRK2/NR4A2/PLAA/RHOA/NRP2/FLNA/COL3A1/NRP1	9
BP	GO:0006066	alcohol metabolic process	13/232	363/18986	0.0358126721763085	2.93077324973877	4.13106569432988	0.000551938302548438	0.00266708447797039	0.00133216345965288	SNCA/HMGCR/APOA1/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2D6/CYP1B1/CYP2R1/ABCA1/PON1/LIPA	13
BP	GO:0002715	regulation of natural killer cell mediated immunity	5/232	55/18986	0.0909090909090909	7.43965517241379	5.31936163809236	0.000552004154116883	0.00266708447797039	0.00133216345965288	IL12B/KLRK1/MICA/HLA-A/HAVCR2	5
BP	GO:0050803	regulation of synapse structure or activity	12/232	318/18986	0.0377358490566038	3.08815875081327	4.17667337441929	0.000567521919940711	0.00273896583483801	0.00136806697821041	NTRK1/NTRK2/SNCA/RHOA/ITGB1/NRP2/EPHB2/EPHB3/EPHB1/HSPA8/INS/TNF	12
BP	GO:0002228	natural killer cell mediated immunity	6/232	84/18986	0.0714285714285714	5.84544334975369	4.95018718310258	0.0005732274827701	0.00275716616009555	0.00137715773197624	IL12B/KLRK1/MICA/HLA-A/FCGR3A/HAVCR2	6
BP	GO:0035023	regulation of Rho protein signal transduction	6/232	84/18986	0.0714285714285714	5.84544334975369	4.95018718310258	0.0005732274827701	0.00275716616009555	0.00137715773197624	APOA1/ITGB1/ABCA1/COL3A1/RAF1/NRP1	6
BP	GO:0051149	positive regulation of muscle cell differentiation	6/232	84/18986	0.0714285714285714	5.84544334975369	4.95018718310258	0.0005732274827701	0.00275716616009555	0.00137715773197624	MMP14/MDM2/LAMA1/LAMB1/LAMB2/BCL2	6
BP	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	3/232	14/18986	0.214285714285714	17.5363300492611	6.88412787667726	0.00059347540814472	0.00284495610451438	0.00142100732018602	ITGAL/ICAM1/HAVCR2	3
BP	GO:0051000	positive regulation of nitric-oxide synthase activity	3/232	14/18986	0.214285714285714	17.5363300492611	6.88412787667726	0.00059347540814472	0.00284495610451438	0.00142100732018602	ESR1/INS/NPR3	3
BP	GO:0060837	blood vessel endothelial cell differentiation	3/232	14/18986	0.214285714285714	17.5363300492611	6.88412787667726	0.00059347540814472	0.00284495610451438	0.00142100732018602	KDR/NRP1/LIPA	3
BP	GO:0062013	positive regulation of small molecule metabolic process	8/232	153/18986	0.0522875816993464	4.27901735406806	4.52930967207363	0.000596800419877231	0.00285281691617018	0.00142493366227889	SNCA/DDB1/APOA1/IGF2/HTR2A/INS/TNF/PTGS2	8
BP	GO:0019883	antigen processing and presentation of endogenous antigen	4/232	32/18986	0.125	10.229525862069	5.81174137073803	0.00059711673058286	0.00285281691617018	0.00142493366227889	ERAP1/ERAP2/MICA/HLA-A	4
BP	GO:0035767	endothelial cell chemotaxis	4/232	32/18986	0.125	10.229525862069	5.81174137073803	0.00059711673058286	0.00285281691617018	0.00142493366227889	VEGFA/KDR/NR4A1/NRP1	4
BP	GO:1902895	positive regulation of miRNA transcription	5/232	56/18986	0.0892857142857143	7.30680418719212	5.25690817627265	0.000600159680994875	0.00286415490617644	0.0014305967959805	EGR1/SMARCA4/TP53/TNF/AR	5
BP	GO:0051960	regulation of nervous system development	15/232	463/18986	0.0323974082073434	2.6512810009682	4.00090421002013	0.000600962865305906	0.002864790648883	0.00143091433867944	VEGFA/NTRK1/NTRK2/ITGB1/PRKCH/TP53/EPHB2/EPHB3/EPHB1/F2/BRAF/NRP1/TNF/PPP3CA/MAPT	15
BP	GO:0045069	regulation of viral genome replication	6/232	85/18986	0.0705882352941176	5.77667342799189	4.90902178695777	0.000610560915751754	0.00290406949472136	0.00145053345595727	DDB1/CXCL8/LTF/PPIA/TNF/BCL2	6
BP	GO:0048041	focal adhesion assembly	6/232	85/18986	0.0705882352941176	5.77667342799189	4.90902178695777	0.000610560915751754	0.00290406949472136	0.00145053345595727	VEGFA/KDR/RHOA/MMP14/NRP1/BCL2	6
BP	GO:0019882	antigen processing and presentation	7/232	118/18986	0.0593220338983051	4.85469023962595	4.67164562627319	0.000621129635712484	0.00295105591367398	0.00147400237527559	ICAM1/IKBKB/ERAP1/LNPEP/ERAP2/MICA/HLA-A	7
BP	GO:0071706	tumor necrosis factor superfamily cytokine production	9/232	193/18986	0.0466321243523316	3.81619617652314	4.37366826512316	0.000631249051470039	0.00299248441694666	0.00149469520998099	FCGR2A/MMP8/EPHB2/LTF/IL12B/PF4/CLEC7A/FCGR3A/HAVCR2	9
BP	GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	9/232	193/18986	0.0466321243523316	3.81619617652314	4.37366826512316	0.000631249051470039	0.00299248441694666	0.00149469520998099	FCGR2A/MMP8/EPHB2/LTF/IL12B/PF4/CLEC7A/FCGR3A/HAVCR2	9
BP	GO:0001570	vasculogenesis	6/232	86/18986	0.0697674418604651	5.70950280673617	4.8685061274803	0.00064975339113616	0.00307425889711412	0.00153554017582702	VEGFA/KDR/NTRK2/PDGFRB/NRP1/NPR2	6
BP	GO:0050982	detection of mechanical stimulus	5/232	57/18986	0.087719298245614	7.1786146400484	5.19597483087239	0.000651397599922046	0.00307425889711412	0.00153554017582702	NTRK1/COL11A1/HTR2A/TNF/TRPA1	5
BP	GO:0099024	plasma membrane invagination	5/232	57/18986	0.087719298245614	7.1786146400484	5.19597483087239	0.000651397599922046	0.00307425889711412	0.00153554017582702	RHOA/MYH9/ITGB2/ABCA1/ALOX15	5
BP	GO:1903351	cellular response to dopamine	5/232	57/18986	0.087719298245614	7.1786146400484	5.19597483087239	0.000651397599922046	0.00307425889711412	0.00153554017582702	HTR3A/HTR3B/FLNA/HTR1A/HTR2A	5
BP	GO:0010594	regulation of endothelial cell migration	10/232	235/18986	0.0425531914893617	3.48239178283199	4.25886993054275	0.000652093737063261	0.00307425889711412	0.00153554017582702	VEGFA/KDR/PRKCA/RHOA/NRP2/NRP1/GRN/TNF/PLG/PTGS2	10
BP	GO:0006941	striated muscle contraction	9/232	194/18986	0.0463917525773196	3.79652506221116	4.35447113681274	0.000655061167360036	0.00308484752382325	0.00154082901527187	PDE5A/PDE4D/PDE4B/CHUK/ALDOA/FLNA/MYH7/NR4A1/TNF	9
BP	GO:0002363	alpha-beta T cell lineage commitment	4/232	33/18986	0.121212121212121	9.91954022988506	5.70378037549032	0.000673016699937278	0.0031589675180371	0.00157785069521375	RHOA/BRD4/IL12B/BCL2	4
BP	GO:0034368	protein-lipid complex remodeling	4/232	33/18986	0.121212121212121	9.91954022988506	5.70378037549032	0.000673016699937278	0.0031589675180371	0.00157785069521375	APOA1/PLA2G2A/PLA2G5/PLA2G10	4
BP	GO:0034369	plasma lipoprotein particle remodeling	4/232	33/18986	0.121212121212121	9.91954022988506	5.70378037549032	0.000673016699937278	0.0031589675180371	0.00157785069521375	APOA1/PLA2G2A/PLA2G5/PLA2G10	4
BP	GO:0001933	negative regulation of protein phosphorylation	10/232	236/18986	0.0423728813559322	3.46763588544711	4.24266537910952	0.000673805141755483	0.00315920042340619	0.00157796702749524	SNCA/PDE4D/PRKCD/PRKCH/CDKN1B/CDKN2A/EPHB2/NTRK3/PPIA/PRKCZ	10
BP	GO:0043535	regulation of blood vessel endothelial cell migration	8/232	156/18986	0.0512820512820513	4.19672855879752	4.45907972687043	0.000678180608158892	0.00317623250874855	0.00158647426523825	VEGFA/KDR/PRKCA/RHOA/NRP1/TNF/PLG/PTGS2	8
BP	GO:1902749	regulation of cell cycle G2/M phase transition	7/232	120/18986	0.0583333333333333	4.77377873563218	4.61242670894948	0.000686591769291943	0.00320790965498384	0.0016022964624987	CDC7/CDK2/ATM/ATR/CDK1/TP53/BRD4	7
BP	GO:0045862	positive regulation of proteolysis	12/232	325/18986	0.0369230769230769	3.02164456233422	4.08866344475479	0.000687194865286528	0.00320790965498384	0.0016022964624987	SNCA/MYH9/HSPA1A/MMP14/CDKN2A/MDM2/COL4A3/HSPA8/GRN/CLEC7A/TNF/MAPT	12
BP	GO:0048638	regulation of developmental growth	12/232	325/18986	0.0369230769230769	3.02164456233422	4.08866344475479	0.000687194865286528	0.00320790965498384	0.0016022964624987	VEGFA/PLAA/CDK1/CDKN1B/IGF2/TGFBR1/NRP1/AR/MAPT/BCL2/SLC6A4/SLC6A3	12
BP	GO:0007422	peripheral nervous system development	6/232	87/18986	0.0689655172413793	5.64387633769322	4.82862187460988	0.00069086757530119	0.00321802805227439	0.00160735043032464	NTRK2/CDK1/COL6A1/LAMB2/RAF1/PLEC	6
BP	GO:0044773	mitotic DNA damage checkpoint signaling	6/232	87/18986	0.0689655172413793	5.64387633769322	4.82862187460988	0.00069086757530119	0.00321802805227439	0.00160735043032464	CDK2/ATM/CDK1/CDKN1B/TP53/MDM2	6
BP	GO:0042220	response to cocaine	5/232	58/18986	0.0862068965517241	7.05484542211653	5.13649690464529	0.000705841703266748	0.00328419926351318	0.00164040182799179	CCNA2/MDM2/HTR2A/SLC6A4/SLC6A3	5
BP	GO:0010721	negative regulation of cell development	11/232	281/18986	0.0391459074733096	3.20355258313904	4.13904415576172	0.000709414727762515	0.00329723627816577	0.00164691359568666	VEGFA/INHBA/TP53/CDKN2A/EPHB2/LTF/F2/NRP1/TNF/PPP3CA/NPR2	11
BP	GO:0019318	hexose metabolic process	10/232	238/18986	0.0420168067226891	3.43849608809041	4.21051682073559	0.000719020979198013	0.00333825592513649	0.00166740221360394	DDB1/RORA/TP53/ALDOA/IGF2/B4GALT1/MAN2B1/INS/LIPA/TNF	10
BP	GO:0140014	mitotic nuclear division	11/232	282/18986	0.0390070921985816	3.19219246759599	4.12513651828507	0.000730427750172416	0.00338753694114669	0.00169201724523328	RHOA/PDGFRB/ATM/HSPA1A/CDK1/CDKN1B/TPX2/FLNA/IGF2/INS/TNF	11
BP	GO:0031329	regulation of cellular catabolic process	15/232	472/18986	0.0317796610169492	2.60072691408533	3.91688169212417	0.000731510205093919	0.00338888151352286	0.00169268883632955	KDR/SNCA/PSAP/CTSA/PRKCD/EEF1A1/ATM/TP53/HTR2A/INS/TNF/HGF/MAPT/BCL2L1/BCL2	15
BP	GO:0055013	cardiac muscle cell development	6/232	88/18986	0.0681818181818182	5.57974137931035	4.78935142260606	0.000733967086953942	0.00339658361884746	0.00169653590730183	VEGFA/PDGFRB/PDGFRA/CDK1/LMNA/PLEC	6
BP	GO:1901160	primary amino compound metabolic process	3/232	15/18986	0.2	16.3672413793103	6.62214624859322	0.000735174710484027	0.00339849412111319	0.00169749017077905	MAOB/HTR1A/SRD5A1	3
BP	GO:0043433	negative regulation of DNA-binding transcription factor activity	8/232	158/18986	0.0506329113924051	4.14360541248363	4.41323256194806	0.000737238988956627	0.00340435628161829	0.00170041822052176	ESR1/CHUK/PLA2G10/CYP1B1/CDKN2A/FLNA/HAVCR2/ADORA3	8
BP	GO:0031330	negative regulation of cellular catabolic process	7/232	122/18986	0.0573770491803279	4.69552006783494	4.55450227963417	0.000757405843085735	0.00349370807447099	0.00174504792553336	SNCA/CTSA/TP53/INS/HGF/BCL2L1/BCL2	7
BP	GO:0050850	positive regulation of calcium-mediated signaling	5/232	59/18986	0.0847457627118644	6.93527177089421	5.07841352630394	0.000763617399321248	0.00351477717922245	0.00175557158599832	PDGFRB/PDGFRA/CLEC7A/TNF/PPP3CA	5
BP	GO:1903350	response to dopamine	5/232	59/18986	0.0847457627118644	6.93527177089421	5.07841352630394	0.000763617399321248	0.00351477717922245	0.00175557158599832	HTR3A/HTR3B/FLNA/HTR1A/HTR2A	5
BP	GO:0007033	vacuole organization	10/232	240/18986	0.0416666666666667	3.40984195402299	4.17870981127619	0.000766710867627856	0.00352522115051259	0.00176078817251491	HEXA/ATM/PLA2G5/MAP1LC3A/EPHB2/ABCA1/HSPA8/GRN/LIPA/NPR2	10
BP	GO:0046718	symbiont entry into host cell	8/232	159/18986	0.050314465408805	4.11754500108436	4.39059187465445	0.000768282996958111	0.00352865531148537	0.00176250347767314	ITGB1/ICAM1/ITGB7/HSPA1A/CDK1/ANPEP/HTR2A/NRP1	8
BP	GO:0140694	non-membrane-bounded organelle assembly	14/232	425/18986	0.0329411764705882	2.69578093306288	3.93247404475791	0.00077531732319904	0.00355714256866856	0.00177673237945658	DDB1/CDK2/RHOA/PDGFRB/PDGFRA/ITGB1/HSPA1A/TPX2/FLNA/MYH7/TNF/AR/MAPT/PLEC	14
BP	GO:0001667	ameboidal-type cell migration	10/232	241/18986	0.04149377593361	3.39569323222206	4.16293224307944	0.000791515451348183	0.00362756706319918	0.00181190821998698	VEGFA/ITGB1/MMP9/EDNRA/ITGB7/NRP2/LAMA5/BRAF/NRP1/PLEC	10
BP	GO:0043405	regulation of MAP kinase activity	7/232	123/18986	0.0569105691056911	4.65734510793384	4.52600941558352	0.000794914938185425	0.0036392465478382	0.00181774192446549	PDE5A/PDGFRB/PRKCD/NTRK3/PDGFA/FLT1/TNF	7
BP	GO:0016525	negative regulation of angiogenesis	8/232	160/18986	0.05	4.09181034482759	4.36813595944925	0.00080037029783039	0.00366030309467674	0.00182825931246593	PDE3B/SHC1/ADAMTS1/COL4A2/COL4A3/PF4/TNF/ALOX5	8
BP	GO:0046394	carboxylic acid biosynthetic process	12/232	331/18986	0.0362537764350453	2.9668715491197	4.01508464903475	0.000805972600525742	0.00368198594000862	0.00183908952594099	PLA2G5/PLA2G10/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2D6/LTA4H/ALOX5/PTGS1/ALOX15/PTGS2	12
BP	GO:0032743	positive regulation of interleukin-2 production	4/232	35/18986	0.114285714285714	9.35270935960591	5.50107623713243	0.00084488201548493	0.00383108748485001	0.00191356321864031	PDE4D/PDE4B/PRKCQ/CLEC7A	4
BP	GO:0034367	protein-containing complex remodeling	4/232	35/18986	0.114285714285714	9.35270935960591	5.50107623713243	0.00084488201548493	0.00383108748485001	0.00191356321864031	APOA1/PLA2G2A/PLA2G5/PLA2G10	4
BP	GO:0043276	anoikis	4/232	35/18986	0.114285714285714	9.35270935960591	5.50107623713243	0.00084488201548493	0.00383108748485001	0.00191356321864031	NTRK2/ITGB1/BCL2L1/BCL2	4
BP	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	4/232	35/18986	0.114285714285714	9.35270935960591	5.50107623713243	0.00084488201548493	0.00383108748485001	0.00191356321864031	BRD4/IL12B/BRAF/BCL2	4
BP	GO:0060191	regulation of lipase activity	4/232	35/18986	0.114285714285714	9.35270935960591	5.50107623713243	0.00084488201548493	0.00383108748485001	0.00191356321864031	SNCA/PLAA/RHOA/PLA2G5	4
BP	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	4/232	35/18986	0.114285714285714	9.35270935960591	5.50107623713243	0.00084488201548493	0.00383108748485001	0.00191356321864031	VEGFA/KDR/NRP1/PTGS2	4
BP	GO:0098810	neurotransmitter reuptake	4/232	35/18986	0.114285714285714	9.35270935960591	5.50107623713243	0.00084488201548493	0.00383108748485001	0.00191356321864031	SNCA/ITGB1/SLC6A4/SLC6A3	4
BP	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	8/232	162/18986	0.0493827160493827	4.04129416773095	4.32376733921093	0.000867777115361624	0.00392657666167863	0.00196125844285016	VEGFA/ITGB2/PRKCD/TP53/HTR2A/PDGFA/NRP1/PRKCZ	8
BP	GO:2000181	negative regulation of blood vessel morphogenesis	8/232	162/18986	0.0493827160493827	4.04129416773095	4.32376733921093	0.000867777115361624	0.00392657666167863	0.00196125844285016	PDE3B/SHC1/ADAMTS1/COL4A2/COL4A3/PF4/TNF/ALOX5	8
BP	GO:0016053	organic acid biosynthetic process	12/232	334/18986	0.0359281437125748	2.94022300227132	3.97891366996301	0.000871516716577829	0.00393932926013404	0.0019676281494786	PLA2G5/PLA2G10/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2D6/LTA4H/ALOX5/PTGS1/ALOX15/PTGS2	12
BP	GO:0044774	mitotic DNA integrity checkpoint signaling	6/232	91/18986	0.0659340659340659	5.3957938613111	4.67505692741386	0.000875827710174734	0.00394630062034474	0.00197111022566085	CDK2/ATM/CDK1/CDKN1B/TP53/MDM2	6
BP	GO:0045995	regulation of embryonic development	6/232	91/18986	0.0659340659340659	5.3957938613111	4.67505692741386	0.000875827710174734	0.00394630062034474	0.00197111022566085	CDK1/LAMA1/LAMA3/LAMA4/LAMA5/HNF4A	6
BP	GO:0097006	regulation of plasma lipoprotein particle levels	6/232	91/18986	0.0659340659340659	5.3957938613111	4.67505692741386	0.000875827710174734	0.00394630062034474	0.00197111022566085	APOA1/PLA2G2A/PLA2G5/PLA2G10/ABCA1/LIPA	6
BP	GO:0032147	activation of protein kinase activity	5/232	61/18986	0.0819672131147541	6.70788581119276	4.96620436201677	0.000889672844748381	0.00400446429909903	0.00200016199666977	PRKCD/TPX2/NTRK3/PPIA/INS	5
BP	GO:0030728	ovulation	3/232	16/18986	0.1875	15.3442887931034	6.3842176352745	0.000896700297581133	0.00400657311646492	0.00200121531517584	MMP2/INHBA/ADAMTS1	3
BP	GO:0034374	low-density lipoprotein particle remodeling	3/232	16/18986	0.1875	15.3442887931034	6.3842176352745	0.000896700297581133	0.00400657311646492	0.00200121531517584	PLA2G2A/PLA2G5/PLA2G10	3
BP	GO:0044849	estrous cycle	3/232	16/18986	0.1875	15.3442887931034	6.3842176352745	0.000896700297581133	0.00400657311646492	0.00200121531517584	EGR1/CYP1B1/HSPA8	3
BP	GO:0050665	hydrogen peroxide biosynthetic process	3/232	16/18986	0.1875	15.3442887931034	6.3842176352745	0.000896700297581133	0.00400657311646492	0.00200121531517584	MAOB/CYP1A1/CYP1A2	3
BP	GO:0071732	cellular response to nitric oxide	3/232	16/18986	0.1875	15.3442887931034	6.3842176352745	0.000896700297581133	0.00400657311646492	0.00200121531517584	CDK2/CCNA2/MMP3	3
BP	GO:0099550	trans-synaptic signaling, modulating synaptic transmission	3/232	16/18986	0.1875	15.3442887931034	6.3842176352745	0.000896700297581133	0.00400657311646492	0.00200121531517584	NTRK2/PLAT/PLG	3
BP	GO:1900034	regulation of cellular response to heat	3/232	16/18986	0.1875	15.3442887931034	6.3842176352745	0.000896700297581133	0.00400657311646492	0.00200121531517584	ATM/ATR/MAPT	3
BP	GO:0071322	cellular response to carbohydrate stimulus	8/232	163/18986	0.049079754601227	4.016500951978	4.30184922855933	0.000903148668808356	0.00403117297267696	0.00201350252610939	PDE8B/CPB2/ICAM1/SMARCA4/COL1A1/RAF1/CLEC7A/PPP3CA	8
BP	GO:0001656	metanephros development	6/232	92/18986	0.0652173913043478	5.33714392803598	4.63807887490294	0.000927523179388056	0.00413134282819097	0.00206353566993242	PDGFRB/PDGFRA/EGR1/LAMB2/PDGFA/BCL2	6
BP	GO:0042100	B cell proliferation	6/232	92/18986	0.0652173913043478	5.33714392803598	4.63807887490294	0.000927523179388056	0.00413134282819097	0.00206353566993242	PRKCD/ATM/CDKN2A/EPHB2/AHR/BCL2	6
BP	GO:1901343	negative regulation of vasculature development	8/232	164/18986	0.0487804878048781	3.99201009251472	4.2801050755405	0.000939667585987077	0.00416739550936577	0.0020815433726806	PDE3B/SHC1/ADAMTS1/COL4A2/COL4A3/PF4/TNF/ALOX5	8
BP	GO:0001975	response to amphetamine	4/232	36/18986	0.111111111111111	9.09291187739464	5.40572305233575	0.000941464934997038	0.00416739550936577	0.0020815433726806	NR4A2/EDNRA/NR4A1/PPP3CA	4
BP	GO:0010613	positive regulation of cardiac muscle hypertrophy	4/232	36/18986	0.111111111111111	9.09291187739464	5.40572305233575	0.000941464934997038	0.00416739550936577	0.0020815433726806	PDE5A/PRKCA/NR4A3/PPP3CA	4
BP	GO:0033687	osteoblast proliferation	4/232	36/18986	0.111111111111111	9.09291187739464	5.40572305233575	0.000941464934997038	0.00416739550936577	0.0020815433726806	RHOA/LTF/NPR3/BCL2	4
BP	GO:0034405	response to fluid shear stress	4/232	36/18986	0.111111111111111	9.09291187739464	5.40572305233575	0.000941464934997038	0.00416739550936577	0.0020815433726806	MMP2/ABCA1/PTGS2/PLEC	4
BP	GO:0036314	response to sterol	4/232	36/18986	0.111111111111111	9.09291187739464	5.40572305233575	0.000941464934997038	0.00416739550936577	0.0020815433726806	INHBA/RORA/ABCA1/TGFBR1	4
BP	GO:0002573	myeloid leukocyte differentiation	10/232	247/18986	0.0404858299595142	3.31320675694541	4.06997798984045	0.000954609569874496	0.00422121046616685	0.00210842303083367	VEGFA/PRKCA/MYH9/INHBA/MMP9/LTF/IL12B/PF4/TNF/PPP3CA	10
BP	GO:0007566	embryo implantation	5/232	62/18986	0.0806451612903226	6.59969410456062	4.911973507406	0.00095821083237326	0.00422703652888179	0.00211133305034246	VEGFA/MMP2/DDR1/MMP9/PTGS2	5
BP	GO:0050879	multicellular organismal movement	5/232	62/18986	0.0806451612903226	6.59969410456062	4.911973507406	0.00095821083237326	0.00422703652888179	0.00211133305034246	CHUK/MYH7/NR4A1/COL6A1/TNF	5
BP	GO:0002832	negative regulation of response to biotic stimulus	7/232	127/18986	0.0551181102362205	4.51065707303828	4.41502611192056	0.000959881307189949	0.00422703652888179	0.00211133305034246	LTF/MICA/HLA-A/GRN/INS/HAVCR2/AHR	7
BP	GO:0006275	regulation of DNA replication	7/232	127/18986	0.0551181102362205	4.51065707303828	4.41502611192056	0.000959881307189949	0.00422703652888179	0.00211133305034246	CDC7/CDK2/CCNA2/ATR/CDK1/CDKN1B/TP53	7
BP	GO:1901991	negative regulation of mitotic cell cycle phase transition	9/232	205/18986	0.0439024390243902	3.59280908326325	4.15136052185813	0.000968939536965344	0.00426253648154713	0.00212906467457514	CDK2/INHBA/ATM/ATR/CDK1/CDKN1B/TP53/MDM2/BCL2	9
BP	GO:0033273	response to vitamin	6/232	93/18986	0.0645161290322581	5.2797552836485	4.60163625547357	0.000981535761241097	0.00431351173182624	0.00215452594748546	CYP1A1/MDM2/ABCA1/COL1A1/LIPA/PTGS2	6
BP	GO:0006813	potassium ion transport	10/232	248/18986	0.0403225806451613	3.29984705228031	4.05476337799243	0.000984296753977546	0.00432120422998766	0.00215836821984269	CRBN/CDK2/ITGB1/KCNA2/KCNQ2/KCNQ5/KCNQ4/CDKN1B/FLNA/HTR2A	10
BP	GO:0031647	regulation of protein stability	13/232	387/18986	0.0335917312661499	2.74901986991001	3.86640875907998	0.000995304268703953	0.00436057484936281	0.00217803317644556	SNCA/APOA1/CTSA/PRKCD/HSPA1A/TP53/CDKN2A/LMNA/FLNA/MDM2/HSPA8/GRN/BCL2	13
BP	GO:0045089	positive regulation of innate immune response	13/232	387/18986	0.0335917312661499	2.74901986991001	3.86640875907998	0.000995304268703953	0.00436057484936281	0.00217803317644556	ESR1/IKBKB/CHUK/HSPA1A/XIAP/PLA2G5/LTF/IL12B/HSPA8/KLRK1/CLEC7A/TNF/HAVCR2	13
BP	GO:0051258	protein polymerization	11/232	293/18986	0.037542662116041	3.07234906437566	3.97612064899929	0.000997773823676387	0.00436692003074742	0.00218120248692495	SNCA/PRKCD/HSPA1A/CDKN1B/TPX2/FGA/FGB/FGG/MAPT/ALOX15/DYRK1A	11
BP	GO:0006913	nucleocytoplasmic transport	12/232	340/18986	0.0352941176470588	2.88833671399594	3.90776458710711	0.00101600892222022	0.0044341918180454	0.00221480360366651	ANP32A/PRKCD/CDK1/CDKN1B/TP53/CDKN2A/LMNA/FLNA/MDM2/HSPA8/PPP3CA/PTGS2	12
BP	GO:0051169	nuclear transport	12/232	340/18986	0.0352941176470588	2.88833671399594	3.90776458710711	0.00101600892222022	0.0044341918180454	0.00221480360366651	ANP32A/PRKCD/CDK1/CDKN1B/TP53/CDKN2A/LMNA/FLNA/MDM2/HSPA8/PPP3CA/PTGS2	12
BP	GO:0033673	negative regulation of kinase activity	8/232	166/18986	0.0481927710843374	3.94391358537599	4.23712844568175	0.00101625537457542	0.0044341918180454	0.00221480360366651	SNCA/PRKCD/PRKCH/CDKN1B/CDKN2A/EPHB2/PPIA/MAPT	8
BP	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	5/232	63/18986	0.0793650793650794	6.49493705528188	4.85892660841323	0.0010305967415149	0.00447848746617652	0.00223692852859834	SNCA/CDKN2A/COL4A3/TNF/MAPT	5
BP	GO:0045058	T cell selection	5/232	63/18986	0.0793650793650794	6.49493705528188	4.85892660841323	0.0010305967415149	0.00447848746617652	0.00223692852859834	RHOA/BRD4/IL12B/BRAF/BCL2	5
BP	GO:0051893	regulation of focal adhesion assembly	5/232	63/18986	0.0793650793650794	6.49493705528188	4.85892660841323	0.0010305967415149	0.00447848746617652	0.00223692852859834	VEGFA/KDR/RHOA/MMP14/NRP1	5
BP	GO:0090109	regulation of cell-substrate junction assembly	5/232	63/18986	0.0793650793650794	6.49493705528188	4.85892660841323	0.0010305967415149	0.00447848746617652	0.00223692852859834	VEGFA/KDR/RHOA/MMP14/NRP1	5
BP	GO:0050777	negative regulation of immune response	9/232	207/18986	0.0434782608695652	3.55809595202399	4.11593122736262	0.00103733078063251	0.00450317402841078	0.00224925904771933	IL12B/COL3A1/MICA/HLA-A/GRN/INS/HAVCR2/AHR/ALOX15	9
BP	GO:0060485	mesenchyme development	12/232	341/18986	0.0351906158357771	2.87986651835373	3.89605739308766	0.00104192729963751	0.00451597614154943	0.00225565348609221	VEGFA/EDNRA/NRP2/FLNA/MDM2/COL1A1/LAMA5/ADAMTS5/TGFBR1/NRP1/HGF/BCL2	12
BP	GO:0014742	positive regulation of muscle hypertrophy	4/232	37/18986	0.108108108108108	8.84715750232992	5.31401065687462	0.00104556042566275	0.00451597614154943	0.00225565348609221	PDE5A/PRKCA/NR4A3/PPP3CA	4
BP	GO:0021955	central nervous system neuron axonogenesis	4/232	37/18986	0.108108108108108	8.84715750232992	5.31401065687462	0.00104556042566275	0.00451597614154943	0.00225565348609221	NR4A2/EPHB2/EPHB3/EPHB1	4
BP	GO:0042462	eye photoreceptor cell development	4/232	37/18986	0.108108108108108	8.84715750232992	5.31401065687462	0.00104556042566275	0.00451597614154943	0.00225565348609221	VEGFA/NTRK2/PDE6C/THRB	4
BP	GO:0046688	response to copper ion	4/232	37/18986	0.108108108108108	8.84715750232992	5.31401065687462	0.00104556042566275	0.00451597614154943	0.00225565348609221	SNCA/CDK1/CYP1A1/MAP1LC3A	4
BP	GO:0035710	CD4-positive, alpha-beta T cell activation	7/232	129/18986	0.0542635658914729	4.44072440523924	4.36124796595303	0.00105188921744061	0.00453872683529367	0.0022670170717372	PRKCQ/RORA/IL18R1/BRD4/IL12B/BRAF/PRKCZ	7
BP	GO:0006606	protein import into nucleus	8/232	167/18986	0.0479041916167665	3.92029733636176	4.21589100254911	0.00105637903049883	0.00455350477259373	0.00227439840076625	PRKCD/CDK1/TP53/LMNA/FLNA/HSPA8/PPP3CA/PTGS2	8
BP	GO:0002679	respiratory burst involved in defense response	3/232	17/18986	0.176470588235294	14.4416835699797	6.16677704666077	0.00107907252607948	0.00460031318196993	0.00229777840732042	GRN/INS/LIPA	3
BP	GO:0007252	I-kappaB phosphorylation	3/232	17/18986	0.176470588235294	14.4416835699797	6.16677704666077	0.00107907252607948	0.00460031318196993	0.00229777840732042	IKBKB/CHUK/TNF	3
BP	GO:0032488	Cdc42 protein signal transduction	3/232	17/18986	0.176470588235294	14.4416835699797	6.16677704666077	0.00107907252607948	0.00460031318196993	0.00229777840732042	APOA1/ABCA1/NRP1	3
BP	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	3/232	17/18986	0.176470588235294	14.4416835699797	6.16677704666077	0.00107907252607948	0.00460031318196993	0.00229777840732042	ATM/ATR/CDKN2A	3
BP	GO:0044320	cellular response to leptin stimulus	3/232	17/18986	0.176470588235294	14.4416835699797	6.16677704666077	0.00107907252607948	0.00460031318196993	0.00229777840732042	CCNA2/NR4A3/FGB	3
BP	GO:0046068	cGMP metabolic process	3/232	17/18986	0.176470588235294	14.4416835699797	6.16677704666077	0.00107907252607948	0.00460031318196993	0.00229777840732042	PDE5A/RORA/NPR2	3
BP	GO:0050872	white fat cell differentiation	3/232	17/18986	0.176470588235294	14.4416835699797	6.16677704666077	0.00107907252607948	0.00460031318196993	0.00229777840732042	FABP4/PDGFRA/NPR2	3
BP	GO:0055091	phospholipid homeostasis	3/232	17/18986	0.176470588235294	14.4416835699797	6.16677704666077	0.00107907252607948	0.00460031318196993	0.00229777840732042	APOA1/ABCA1/HNF4A	3
BP	GO:0061548	ganglion development	3/232	17/18986	0.176470588235294	14.4416835699797	6.16677704666077	0.00107907252607948	0.00460031318196993	0.00229777840732042	NRP2/CYP1B1/NRP1	3
BP	GO:1901550	regulation of endothelial cell development	3/232	17/18986	0.176470588235294	14.4416835699797	6.16677704666077	0.00107907252607948	0.00460031318196993	0.00229777840732042	VEGFA/IKBKB/TNF	3
BP	GO:1903140	regulation of establishment of endothelial barrier	3/232	17/18986	0.176470588235294	14.4416835699797	6.16677704666077	0.00107907252607948	0.00460031318196993	0.00229777840732042	VEGFA/IKBKB/TNF	3
BP	GO:0007264	small GTPase-mediated signal transduction	15/232	491/18986	0.0305498981670061	2.5000877870637	3.74569654891836	0.00108789244398006	0.00463329491081547	0.00231425222146733	NTRK1/CDK2/CCNA2/RHOA/APOA1/ITGB1/TP53/CDKN2A/EPHB2/ABCA1/COL1A2/COL3A1/RAF1/NRP1/LIPA	15
BP	GO:0007584	response to nutrient	8/232	168/18986	0.0476190476190476	3.89696223316913	4.19481758164975	0.00109775961553808	0.00467066678213018	0.00233291883731528	CYP1A1/CYP1B1/MDM2/ABCA1/COL1A1/LIPA/PTGS2/SLC6A4	8
BP	GO:0002761	regulation of myeloid leukocyte differentiation	7/232	130/18986	0.0538461538461538	4.4065649867374	4.33476848331862	0.00110041973401515	0.00467268598078331	0.00233392739279438	PRKCA/INHBA/LTF/IL12B/PF4/TNF/PPP3CA	7
BP	GO:0021987	cerebral cortex development	7/232	130/18986	0.0538461538461538	4.4065649867374	4.33476848331862	0.00110041973401515	0.00467268598078331	0.00233392739279438	NTRK2/RHOA/KCNA2/FLNA/COL3A1/LAMB1/SRD5A1	7
BP	GO:0002763	positive regulation of myeloid leukocyte differentiation	5/232	64/18986	0.078125	6.3934536637931	4.80701809833313	0.00110696295921129	0.00468187301047227	0.00233851615830048	PRKCA/IL12B/PF4/TNF/PPP3CA	5
BP	GO:0010324	membrane invagination	5/232	64/18986	0.078125	6.3934536637931	4.80701809833313	0.00110696295921129	0.00468187301047227	0.00233851615830048	RHOA/MYH9/ITGB2/ABCA1/ALOX15	5
BP	GO:0046824	positive regulation of nucleocytoplasmic transport	5/232	64/18986	0.078125	6.3934536637931	4.80701809833313	0.00110696295921129	0.00468187301047227	0.00233851615830048	PRKCD/CDK1/FLNA/MDM2/PTGS2	5
BP	GO:0051785	positive regulation of nuclear division	5/232	64/18986	0.078125	6.3934536637931	4.80701809833313	0.00110696295921129	0.00468187301047227	0.00233851615830048	PDGFRB/IGF2/INS/TNF/NPR2	5
BP	GO:0002758	innate immune response-activating signaling pathway	11/232	297/18986	0.037037037037037	3.03097062579821	3.92365823922197	0.00111311746849826	0.00469860838627697	0.002346875194662	ESR1/IKBKB/CHUK/HSPA1A/XIAP/LTF/HSPA8/KLRK1/CLEC7A/TNF/HAVCR2	11
BP	GO:0045165	cell fate commitment	11/232	297/18986	0.037037037037037	3.03097062579821	3.92365823922197	0.00111311746849826	0.00469860838627697	0.002346875194662	KDR/RHOA/ITGB1/EDNRA/TP53/BRD4/IL12B/BRAF/TGFBR1/NRP1/BCL2	11
BP	GO:0055007	cardiac muscle cell differentiation	7/232	131/18986	0.0534351145038168	4.37292708607528	4.30855528333416	0.00115069138839532	0.00485242246230609	0.00242370271675916	VEGFA/PDGFRB/PDGFRA/ITGB1/CDK1/LMNA/PLEC	7
BP	GO:0046677	response to antibiotic	4/232	38/18986	0.105263157894737	8.61433756805808	5.22570120716565	0.00115747778927942	0.00485999498106294	0.0024274850614388	CDKN1B/TP53/MDM2/SRD5A1	4
BP	GO:0010507	negative regulation of autophagy	6/232	96/18986	0.0625	5.11476293103448	4.49538398056325	0.00115816999197922	0.00485999498106294	0.0024274850614388	SNCA/CTSA/TP53/HGF/BCL2L1/BCL2	6
BP	GO:0015837	amine transport	6/232	96/18986	0.0625	5.11476293103448	4.49538398056325	0.00115816999197922	0.00485999498106294	0.0024274850614388	SNCA/ITGB1/KCNA2/HTR2A/TNF/ADORA3	6
BP	GO:0043502	regulation of muscle adaptation	6/232	96/18986	0.0625	5.11476293103448	4.49538398056325	0.00115816999197922	0.00485999498106294	0.0024274850614388	PDE5A/PRKCA/NR4A3/LMNA/MYH7/PPP3CA	6
BP	GO:0097194	execution phase of apoptosis	6/232	96/18986	0.0625	5.11476293103448	4.49538398056325	0.00115816999197922	0.00485999498106294	0.0024274850614388	TP53/CDKN2A/COL6A1/HTR2A/NPR2/BCL2L1	6
BP	GO:0031113	regulation of microtubule polymerization	5/232	65/18986	0.0769230769230769	6.29509283819629	4.75620485346887	0.00118744304601446	0.00496334942791577	0.00247910885462092	SNCA/HSPA1A/CDKN1B/MAPT/DYRK1A	5
BP	GO:0051937	catecholamine transport	5/232	65/18986	0.0769230769230769	6.29509283819629	4.75620485346887	0.00118744304601446	0.00496334942791577	0.00247910885462092	SNCA/KCNA2/HTR2A/SLC6A3/ADORA3	5
BP	GO:0051965	positive regulation of synapse assembly	5/232	65/18986	0.0769230769230769	6.29509283819629	4.75620485346887	0.00118744304601446	0.00496334942791577	0.00247910885462092	NTRK1/NTRK2/EPHB2/EPHB3/EPHB1	5
BP	GO:1905330	regulation of morphogenesis of an epithelium	5/232	65/18986	0.0769230769230769	6.29509283819629	4.75620485346887	0.00118744304601446	0.00496334942791577	0.00247910885462092	VEGFA/ESR1/PDGFA/TNF/HGF	5
BP	GO:0051899	membrane depolarization	6/232	97/18986	0.0618556701030928	5.06203341628155	4.4609485357431	0.00122214888757127	0.00510342640942847	0.00254907493100545	KDR/CDKN2A/COL6A1/PRKCZ/BCL2/SLC6A4	6
BP	GO:0048639	positive regulation of developmental growth	8/232	171/18986	0.0467836257309941	3.82859447469248	4.13255811753883	0.00122972698246581	0.00512506099125126	0.00255988103767633	VEGFA/PLAA/CDK1/IGF2/NRP1/MAPT/BCL2/SLC6A3	8
BP	GO:0061351	neural precursor cell proliferation	8/232	171/18986	0.0467836257309941	3.82859447469248	4.13255811753883	0.00122972698246581	0.00512506099125126	0.00255988103767633	VEGFA/RHOA/ITGB1/RORA/TP53/EPHB1/FLNA/SLC6A4	8
BP	GO:0062012	regulation of small molecule metabolic process	12/232	348/18986	0.0344827586206897	2.82193816884661	3.81527581748275	0.00123920475672382	0.00515953217113052	0.00257709880735164	SNCA/DDB1/APOA1/EGR1/RORA/TP53/IGF2/HTR2A/INS/TNF/HNF4A/PTGS2	12
BP	GO:0045930	negative regulation of mitotic cell cycle	10/232	256/18986	0.0390625	3.19672683189655	3.9357679611762	0.00125012772579374	0.0051999476220759	0.00259728563960219	CDK2/INHBA/ATM/ATR/CDK1/CDKN1B/TP53/MDM2/TNF/BCL2	10
BP	GO:0006518	peptide metabolic process	5/232	66/18986	0.0757575757575758	6.19971264367816	4.70644602668889	0.0012721716616089	0.00526602712975764	0.002630291232898	ERAP1/ANPEP/LNPEP/ERAP2/LTA4H	5
BP	GO:0010812	negative regulation of cell-substrate adhesion	5/232	66/18986	0.0757575757575758	6.19971264367816	4.70644602668889	0.0012721716616089	0.00526602712975764	0.002630291232898	RHOA/MMP14/CDKN2A/COL1A1/PLG	5
BP	GO:0032623	interleukin-2 production	5/232	66/18986	0.0757575757575758	6.19971264367816	4.70644602668889	0.0012721716616089	0.00526602712975764	0.002630291232898	PDE4D/PDE4B/PRKCQ/CLEC7A/HAVCR2	5
BP	GO:0032663	regulation of interleukin-2 production	5/232	66/18986	0.0757575757575758	6.19971264367816	4.70644602668889	0.0012721716616089	0.00526602712975764	0.002630291232898	PDE4D/PDE4B/PRKCQ/CLEC7A/HAVCR2	5
BP	GO:1901224	positive regulation of non-canonical NF-kappaB signal transduction	5/232	66/18986	0.0757575757575758	6.19971264367816	4.70644602668889	0.0012721716616089	0.00526602712975764	0.002630291232898	RHOA/IL18R1/IL12B/TNF/HAVCR2	5
BP	GO:0051170	import into nucleus	8/232	172/18986	0.0465116279069767	3.80633520449078	4.11211768553597	0.00127642098288321	0.00526606979992206	0.00263031254592139	PRKCD/CDK1/TP53/LMNA/FLNA/HSPA8/PPP3CA/PTGS2	8
BP	GO:0048741	skeletal muscle fiber development	4/232	39/18986	0.102564102564103	8.39345711759505	5.14057821702797	0.00127752594480635	0.00526606979992206	0.00263031254592139	COL6A1/PPP3CA/BCL2/PLEC	4
BP	GO:0060323	head morphogenesis	4/232	39/18986	0.102564102564103	8.39345711759505	5.14057821702797	0.00127752594480635	0.00526606979992206	0.00263031254592139	MMP2/PDGFRA/COL1A1/BRAF	4
BP	GO:0002827	positive regulation of T-helper 1 type immune response	3/232	18/18986	0.166666666666667	13.639367816092	5.9669606216897	0.00128326583992488	0.00526606979992206	0.00263031254592139	IL1R1/IL18R1/IL12B	3
BP	GO:0010517	regulation of phospholipase activity	3/232	18/18986	0.166666666666667	13.639367816092	5.9669606216897	0.00128326583992488	0.00526606979992206	0.00263031254592139	SNCA/PLAA/PLA2G5	3
BP	GO:0031649	heat generation	3/232	18/18986	0.166666666666667	13.639367816092	5.9669606216897	0.00128326583992488	0.00526606979992206	0.00263031254592139	HTR2A/TNF/PTGS2	3
BP	GO:0032148	activation of protein kinase B activity	3/232	18/18986	0.166666666666667	13.639367816092	5.9669606216897	0.00128326583992488	0.00526606979992206	0.00263031254592139	NTRK3/PPIA/INS	3
BP	GO:0055119	relaxation of cardiac muscle	3/232	18/18986	0.166666666666667	13.639367816092	5.9669606216897	0.00128326583992488	0.00526606979992206	0.00263031254592139	PDE5A/PDE4D/PDE4B	3
BP	GO:1902170	cellular response to reactive nitrogen species	3/232	18/18986	0.166666666666667	13.639367816092	5.9669606216897	0.00128326583992488	0.00526606979992206	0.00263031254592139	CDK2/CCNA2/MMP3	3
BP	GO:0031669	cellular response to nutrient levels	10/232	257/18986	0.0389105058365759	3.18428820609151	3.92122303329862	0.00128712232467384	0.00527683131381146	0.00263568773958039	INHBA/PRKCH/HSPA5/MAP1LC3A/TP53/MDM2/COL1A1/HSPA8/BCL2/SRD5A1	10
BP	GO:0048706	embryonic skeletal system development	7/232	134/18986	0.0522388059701493	4.27502573340196	4.23146485155345	0.00131238772562324	0.00537525853904689	0.00268485046913646	PDGFRA/EDNRA/MMP14/COL1A1/COL2A1/COL11A1/TGFBR1	7
BP	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	6/232	99/18986	0.0606060606060606	4.95977011494253	4.39347761623362	0.00135818966168858	0.0055436690296888	0.00276896865275924	SNCA/CDKN2A/COL4A3/CLEC7A/TNF/MAPT	6
BP	GO:0050848	regulation of calcium-mediated signaling	6/232	99/18986	0.0606060606060606	4.95977011494253	4.39347761623362	0.00135818966168858	0.0055436690296888	0.00276896865275924	PDGFRB/PDGFRA/CLEC7A/TNF/PPP3CA/MAPT	6
BP	GO:0030888	regulation of B cell proliferation	5/232	67/18986	0.0746268656716418	6.10717961914565	4.65770289465861	0.00136128449045211	0.0055436690296888	0.00276896865275924	ATM/CDKN2A/EPHB2/AHR/BCL2	5
BP	GO:0031100	animal organ regeneration	5/232	67/18986	0.0746268656716418	6.10717961914565	4.65770289465861	0.00136128449045211	0.0055436690296888	0.00276896865275924	CCNA2/NR4A3/CPB2/CDK1/TNF	5
BP	GO:0050994	regulation of lipid catabolic process	5/232	67/18986	0.0746268656716418	6.10717961914565	4.65770289465861	0.00136128449045211	0.0055436690296888	0.00276896865275924	PDE3B/PRKCD/THRA/INS/TNF	5
BP	GO:2000630	positive regulation of miRNA metabolic process	5/232	67/18986	0.0746268656716418	6.10717961914565	4.65770289465861	0.00136128449045211	0.0055436690296888	0.00276896865275924	EGR1/SMARCA4/TP53/TNF/AR	5
BP	GO:0000280	nuclear division	14/232	451/18986	0.0310421286031042	2.540370058873	3.68230181063762	0.00136498934313231	0.00555346758442792	0.00277386286465567	DDB1/PDE3A/RHOA/PDGFRB/ATM/HSPA1A/CDK1/CDKN1B/TPX2/FLNA/IGF2/INS/TNF/NPR2	14
BP	GO:0002369	T cell cytokine production	4/232	40/18986	0.1	8.18362068965517	5.0584441475561	0.00140601312176934	0.00568252562257627	0.00283832516572479	IL1R1/IL18R1/HLA-A/PRKCZ	4
BP	GO:0002724	regulation of T cell cytokine production	4/232	40/18986	0.1	8.18362068965517	5.0584441475561	0.00140601312176934	0.00568252562257627	0.00283832516572479	IL1R1/IL18R1/HLA-A/PRKCZ	4
BP	GO:0032814	regulation of natural killer cell activation	4/232	40/18986	0.1	8.18362068965517	5.0584441475561	0.00140601312176934	0.00568252562257627	0.00283832516572479	IL12B/MICA/FCGR3A/HAVCR2	4
BP	GO:0033028	myeloid cell apoptotic process	4/232	40/18986	0.1	8.18362068965517	5.0584441475561	0.00140601312176934	0.00568252562257627	0.00283832516572479	THRA/CDKN2A/LIPA/BCL2	4
BP	GO:0038179	neurotrophin signaling pathway	4/232	40/18986	0.1	8.18362068965517	5.0584441475561	0.00140601312176934	0.00568252562257627	0.00283832516572479	NTRK1/NTRK2/NTRK3/RAF1	4
BP	GO:0045730	respiratory burst	4/232	40/18986	0.1	8.18362068965517	5.0584441475561	0.00140601312176934	0.00568252562257627	0.00283832516572479	GRN/INS/CLEC7A/LIPA	4
BP	GO:0048873	homeostasis of number of cells within a tissue	4/232	40/18986	0.1	8.18362068965517	5.0584441475561	0.00140601312176934	0.00568252562257627	0.00283832516572479	VEGFA/XIAP/LIPA/BCL2	4
BP	GO:0042476	odontogenesis	7/232	136/18986	0.0514705882352941	4.21215770791075	4.18131584345515	0.00142969625280174	0.00575930520681545	0.00287667526577434	RHOA/PDGFRA/INHBA/COL1A2/COL1A1/LAMA5/LAMB1	7
BP	GO:0045931	positive regulation of mitotic cell cycle	7/232	136/18986	0.0514705882352941	4.21215770791075	4.18131584345515	0.00142969625280174	0.00575930520681545	0.00287667526577434	CDC7/PRKCA/CDK1/ADAMTS1/CYP1A1/MDM2/BRD4	7
BP	GO:0048593	camera-type eye morphogenesis	7/232	136/18986	0.0514705882352941	4.21215770791075	4.18131584345515	0.00142969625280174	0.00575930520681545	0.00287667526577434	VEGFA/KDR/NTRK2/PDE6C/EPHB2/EPHB1/THRB	7
BP	GO:0031110	regulation of microtubule polymerization or depolymerization	6/232	100/18986	0.06	4.9101724137931	4.3604192887567	0.00143039806586483	0.00575930520681545	0.00287667526577434	SNCA/HSPA1A/CDKN1B/TPX2/MAPT/DYRK1A	6
BP	GO:0034765	regulation of monoatomic ion transmembrane transport	12/232	354/18986	0.0338983050847458	2.77410870835769	3.74761059652082	0.00143207306707986	0.00576062505628739	0.00287733450819928	SNCA/CRBN/PDE4D/PDE4B/ITGB1/MMP9/EDNRA/EPHB2/FLNA/F2/PPP3CA/BCL2	12
BP	GO:0150116	regulation of cell-substrate junction organization	5/232	68/18986	0.0735294117647059	6.01736815415821	4.6099387174378	0.00145491816750761	0.00584702075588583	0.00292048769476942	VEGFA/KDR/RHOA/MMP14/NRP1	5
BP	GO:0005996	monosaccharide metabolic process	10/232	262/18986	0.0381679389312977	3.12351934719663	3.84954932717393	0.00148573645630943	0.00596526674852499	0.00297954956249254	DDB1/RORA/TP53/ALDOA/IGF2/B4GALT1/MAN2B1/INS/LIPA/TNF	10
BP	GO:0010657	muscle cell apoptotic process	6/232	101/18986	0.0594059405940594	4.86155684533971	4.3277978025094	0.00150549734976372	0.00599596818298186	0.00299488440826896	ESR1/TP53/CDKN2A/IL12B/COL6A1/HSPA8	6
BP	GO:0046785	microtubule polymerization	6/232	101/18986	0.0594059405940594	4.86155684533971	4.3277978025094	0.00150549734976372	0.00599596818298186	0.00299488440826896	SNCA/HSPA1A/CDKN1B/TPX2/MAPT/DYRK1A	6
BP	GO:0001502	cartilage condensation	3/232	19/18986	0.157894736842105	12.9215063520871	5.78243753844468	0.00151020994692971	0.00599596818298186	0.00299488440826896	THRA/COL2A1/COL11A1	3
BP	GO:0002281	macrophage activation involved in immune response	3/232	19/18986	0.157894736842105	12.9215063520871	5.78243753844468	0.00151020994692971	0.00599596818298186	0.00299488440826896	GRN/TNF/HAVCR2	3
BP	GO:0003417	growth plate cartilage development	3/232	19/18986	0.157894736842105	12.9215063520871	5.78243753844468	0.00151020994692971	0.00599596818298186	0.00299488440826896	MMP13/COL27A1/NPR2	3
BP	GO:0007190	activation of adenylate cyclase activity	3/232	19/18986	0.157894736842105	12.9215063520871	5.78243753844468	0.00151020994692971	0.00599596818298186	0.00299488440826896	EDNRA/RAF1/ADORA3	3
BP	GO:0030540	female genitalia development	3/232	19/18986	0.157894736842105	12.9215063520871	5.78243753844468	0.00151020994692971	0.00599596818298186	0.00299488440826896	ESR1/NPR2/SRD5A1	3
BP	GO:0030903	notochord development	3/232	19/18986	0.157894736842105	12.9215063520871	5.78243753844468	0.00151020994692971	0.00599596818298186	0.00299488440826896	COL2A1/COL18A1/COL27A1	3
BP	GO:0035743	CD4-positive, alpha-beta T cell cytokine production	3/232	19/18986	0.157894736842105	12.9215063520871	5.78243753844468	0.00151020994692971	0.00599596818298186	0.00299488440826896	IL1R1/IL18R1/PRKCZ	3
BP	GO:0042402	cellular biogenic amine catabolic process	3/232	19/18986	0.157894736842105	12.9215063520871	5.78243753844468	0.00151020994692971	0.00599596818298186	0.00299488440826896	MAOA/MAOB/SLC6A3	3
BP	GO:0060263	regulation of respiratory burst	3/232	19/18986	0.157894736842105	12.9215063520871	5.78243753844468	0.00151020994692971	0.00599596818298186	0.00299488440826896	GRN/INS/CLEC7A	3
BP	GO:0090201	negative regulation of release of cytochrome c from mitochondria	3/232	19/18986	0.157894736842105	12.9215063520871	5.78243753844468	0.00151020994692971	0.00599596818298186	0.00299488440826896	LMNA/HGF/BCL2L1	3
BP	GO:0001916	positive regulation of T cell mediated cytotoxicity	4/232	41/18986	0.0975609756097561	7.98402018502944	4.97911832164972	0.00154324656637539	0.00610446097855796	0.00304907471948552	IL12B/HSPA8/MICA/HLA-A	4
BP	GO:0042307	positive regulation of protein import into nucleus	4/232	41/18986	0.0975609756097561	7.98402018502944	4.97911832164972	0.00154324656637539	0.00610446097855796	0.00304907471948552	PRKCD/CDK1/FLNA/PTGS2	4
BP	GO:0072210	metanephric nephron development	4/232	41/18986	0.0975609756097561	7.98402018502944	4.97911832164972	0.00154324656637539	0.00610446097855796	0.00304907471948552	PDGFRB/PDGFRA/EGR1/LAMB2	4
BP	GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	4/232	41/18986	0.0975609756097561	7.98402018502944	4.97911832164972	0.00154324656637539	0.00610446097855796	0.00304907471948552	RHOA/ITGB2/TNF/ALOX5	4
BP	GO:0010611	regulation of cardiac muscle hypertrophy	5/232	69/18986	0.072463768115942	5.93015992003998	4.56311860927665	0.00155321020413724	0.00612122288745699	0.00305744700867762	PDE5A/PRKCA/NR4A3/LMNA/PPP3CA	5
BP	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	5/232	69/18986	0.072463768115942	5.93015992003998	4.56311860927665	0.00155321020413724	0.00612122288745699	0.00305744700867762	APOA1/IKBKB/MMP8/HSPA1A/XIAP	5
BP	GO:0030225	macrophage differentiation	5/232	69/18986	0.072463768115942	5.93015992003998	4.56311860927665	0.00155321020413724	0.00612122288745699	0.00305744700867762	VEGFA/PRKCA/INHBA/MMP9/PF4	5
BP	GO:0071300	cellular response to retinoic acid	5/232	69/18986	0.072463768115942	5.93015992003998	4.56311860927665	0.00155321020413724	0.00612122288745699	0.00305744700867762	ATM/ABCA1/COL1A1/TNF/SLC6A4	5
BP	GO:0006959	humoral immune response	11/232	310/18986	0.0354838709677419	2.90386540600667	3.75904473626213	0.00156643512949662	0.00616765802369019	0.00308064057162803	MASP2/CXCL8/LTF/F2/FGA/FGB/PF4/HLA-A/TNF/ALOX5/BCL2	11
BP	GO:0048167	regulation of synaptic plasticity	9/232	220/18986	0.0409090909090909	3.34784482758621	3.8958050134711	0.00158331194799782	0.0062122140700063	0.00310289556103658	NTRK2/SNCA/HMGCR/EPHB2/BRAF/INS/PRKCZ/MAPT/PTGS2	9
BP	GO:0003300	cardiac muscle hypertrophy	6/232	102/18986	0.0588235294117647	4.81389452332657	4.29560268753124	0.00158356252018402	0.0062122140700063	0.00310289556103658	PDE5A/PRKCA/NR4A3/LMNA/MYH7/PPP3CA	6
BP	GO:0030101	natural killer cell activation	6/232	102/18986	0.0588235294117647	4.81389452332657	4.29560268753124	0.00158356252018402	0.0062122140700063	0.00310289556103658	IL18R1/IL12B/KLRK1/MICA/FCGR3A/HAVCR2	6
BP	GO:0043367	CD4-positive, alpha-beta T cell differentiation	6/232	102/18986	0.0588235294117647	4.81389452332657	4.29560268753124	0.00158356252018402	0.0062122140700063	0.00310289556103658	RORA/IL18R1/BRD4/IL12B/BRAF/PRKCZ	6
BP	GO:0042593	glucose homeostasis	10/232	265/18986	0.0377358490566038	3.08815875081327	3.80736282544742	0.00161640276535565	0.00633523210326375	0.00316434098210874	PDE8B/CPB2/ICAM1/SMARCA4/COL1A1/RAF1/INS/PPP3CA/HNF4A/ALOX5	10
BP	GO:0030183	B cell differentiation	7/232	139/18986	0.0503597122302158	4.12124782932275	4.10787174337109	0.00162083331133855	0.00634677952315353	0.00317010872248499	NTRK1/ITGB1/INHBA/ATM/MMP14/TP53/BCL2	7
BP	GO:0033500	carbohydrate homeostasis	10/232	266/18986	0.037593984962406	3.07654913144931	3.79343323220665	0.00166197442350074	0.0065005713948708	0.00324692515390499	PDE8B/CPB2/ICAM1/SMARCA4/COL1A1/RAF1/INS/PPP3CA/HNF4A/ALOX5	10
BP	GO:0043279	response to alkaloid	6/232	103/18986	0.058252427184466	4.76715768329427	4.26382382662024	0.00166466924167061	0.0065005713948708	0.00324692515390499	CCNA2/MDM2/HTR2A/BCL2L1/SLC6A4/SLC6A3	6
BP	GO:2000177	regulation of neural precursor cell proliferation	6/232	103/18986	0.058252427184466	4.76715768329427	4.26382382662024	0.00166466924167061	0.0065005713948708	0.00324692515390499	VEGFA/RHOA/ITGB1/TP53/FLNA/SLC6A4	6
BP	GO:0032733	positive regulation of interleukin-10 production	4/232	42/18986	0.0952380952380952	7.79392446633826	4.90243511271998	0.00168953225999035	0.00658563349472993	0.00328941223002487	IL12B/CLEC7A/PRKCZ/HGF	4
BP	GO:0050433	regulation of catecholamine secretion	4/232	42/18986	0.0952380952380952	7.79392446633826	4.90243511271998	0.00168953225999035	0.00658563349472993	0.00328941223002487	SNCA/KCNA2/HTR2A/ADORA3	4
BP	GO:0016052	carbohydrate catabolic process	8/232	180/18986	0.0444444444444444	3.63716475095785	3.95391779931426	0.00170297503493717	0.00662595200126602	0.00330955064018728	TP53/ALDOA/COL6A1/HTR2A/MAN2B1/INS/MANBA/LIPA	8
BP	GO:0055088	lipid homeostasis	8/232	180/18986	0.0444444444444444	3.63716475095785	3.95391779931426	0.00170297503493717	0.00662595200126602	0.00330955064018728	FABP4/APOA1/RORA/PLA2G10/ABCA1/INS/LIPA/HNF4A	8
BP	GO:0045619	regulation of lymphocyte differentiation	9/232	223/18986	0.0403587443946188	3.30280655636307	3.84734459828052	0.00173733113099504	0.0067534799237589	0.00337324867443917	RHOA/INHBA/SMARCA4/MMP14/CDKN2A/BRD4/IL12B/BRAF/PRKCZ	9
BP	GO:0042102	positive regulation of T cell proliferation	6/232	104/18986	0.0576923076923077	4.72131962864721	4.23245144012623	0.00174889381392157	0.00679225245079802	0.00339261489406459	PRKCQ/IGF2/IL12B/HLA-A/PPP3CA/HAVCR2	6
BP	GO:0032634	interleukin-5 production	3/232	20/18986	0.15	12.2754310344828	5.61128871774689	0.00176079097113608	0.00680139312789328	0.00339718050723634	PDE4D/IL17RA/PRKCZ	3
BP	GO:0032674	regulation of interleukin-5 production	3/232	20/18986	0.15	12.2754310344828	5.61128871774689	0.00176079097113608	0.00680139312789328	0.00339718050723634	PDE4D/IL17RA/PRKCZ	3
BP	GO:0045472	response to ether	3/232	20/18986	0.15	12.2754310344828	5.61128871774689	0.00176079097113608	0.00680139312789328	0.00339718050723634	CYP1A1/MDM2/LIPA	3
BP	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	3/232	20/18986	0.15	12.2754310344828	5.61128871774689	0.00176079097113608	0.00680139312789328	0.00339718050723634	MICA/HLA-A/HAVCR2	3
BP	GO:0055093	response to hyperoxia	3/232	20/18986	0.15	12.2754310344828	5.61128871774689	0.00176079097113608	0.00680139312789328	0.00339718050723634	MMP2/CYP1A1/COL1A1	3
BP	GO:1903978	regulation of microglial cell activation	3/232	20/18986	0.15	12.2754310344828	5.61128871774689	0.00176079097113608	0.00680139312789328	0.00339718050723634	ATM/MMP8/GRN	3
BP	GO:0001912	positive regulation of leukocyte mediated cytotoxicity	5/232	71/18986	0.0704225352112676	5.763113161729	4.47217962303346	0.00176432334053904	0.00680888682684561	0.00340092348276051	IL12B/HSPA8/KLRK1/MICA/HLA-A	5
BP	GO:0014897	striated muscle hypertrophy	6/232	105/18986	0.0571428571428571	4.67635467980296	4.20147607153928	0.00183631314892559	0.00707394146378902	0.00353331377825512	PDE5A/PRKCA/NR4A3/LMNA/MYH7/PPP3CA	6
BP	GO:1901992	positive regulation of mitotic cell cycle phase transition	6/232	105/18986	0.0571428571428571	4.67635467980296	4.20147607153928	0.00183631314892559	0.00707394146378902	0.00353331377825512	CDC7/CDK1/ADAMTS1/CYP1A1/MDM2/BRD4	6
BP	GO:0001662	behavioral fear response	4/232	43/18986	0.0930232558139535	7.61267040898156	4.82824236594022	0.00184517464963987	0.00708771406868405	0.00354019296079955	PDE8B/EPHB2/HTR1A/BCL2	4
BP	GO:0014904	myotube cell development	4/232	43/18986	0.0930232558139535	7.61267040898156	4.82824236594022	0.00184517464963987	0.00708771406868405	0.00354019296079955	COL6A1/PPP3CA/BCL2/PLEC	4
BP	GO:0045740	positive regulation of DNA replication	4/232	43/18986	0.0930232558139535	7.61267040898156	4.82824236594022	0.00184517464963987	0.00708771406868405	0.00354019296079955	CDC7/CDK2/CDK1/CDKN1B	4
BP	GO:0032409	regulation of transporter activity	9/232	225/18986	0.04	3.27344827586207	3.81549318799518	0.00184651858571423	0.00708771406868405	0.00354019296079955	SNCA/CRBN/ITGB1/MMP9/EDNRA/PRKCD/EPHB2/INS/BCL2	9
BP	GO:0002218	activation of innate immune response	11/232	317/18986	0.0347003154574132	2.83974219514848	3.67390912537831	0.00186716991044677	0.00716055474176715	0.00357657564153551	ESR1/IKBKB/CHUK/HSPA1A/XIAP/LTF/HSPA8/KLRK1/CLEC7A/TNF/HAVCR2	11
BP	GO:0014743	regulation of muscle hypertrophy	5/232	72/18986	0.0694444444444444	5.68306992337165	4.42799921828175	0.001877423181553	0.00719342430494681	0.00359299343083479	PDE5A/PRKCA/NR4A3/LMNA/PPP3CA	5
BP	GO:0072331	signal transduction by p53 class mediator	8/232	183/18986	0.0437158469945355	3.57753909930281	3.89690277973071	0.00188928112963462	0.00723237789643477	0.00361245008908132	ATM/ATR/CDKN1B/TP53/CDKN2A/MDM2/BCL2/DYRK1A	8
BP	GO:1904062	regulation of monoatomic cation transmembrane transport	11/232	318/18986	0.0345911949685535	2.8308121882455	3.66193639120069	0.001913737102289	0.00731944530356688	0.00365593878217153	SNCA/CRBN/PDE4D/PDE4B/ITGB1/MMP9/EDNRA/FLNA/F2/PPP3CA/BCL2	11
BP	GO:0042632	cholesterol homeostasis	6/232	106/18986	0.0566037735849057	4.63223812621991	4.17088857382484	0.00192700474784646	0.00736360348685566	0.00367799504574618	FABP4/APOA1/RORA/PLA2G10/ABCA1/HNF4A	6
BP	GO:0009895	negative regulation of catabolic process	12/232	367/18986	0.0326975476839237	2.67584327727145	3.60570834510371	0.00193590345035285	0.00739100281581143	0.00369168054583265	SNCA/HMGCR/PDE3B/CTSA/TP53/CDKN2A/FLNA/INS/TNF/HGF/BCL2L1/BCL2	12
BP	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	8/232	184/18986	0.0434782608695652	3.55809595202399	3.87816296903995	0.00195483405156917	0.00745661945094539	0.00372445494214175	PDE4A/PDE3A/PDE4D/PDE4B/PDE3B/PRKCA/ABCA1/PF4	8
BP	GO:0009581	detection of external stimulus	7/232	144/18986	0.0486111111111111	3.97814894636015	3.98994122309204	0.00198298473392679	0.00755725732822724	0.00377472185489958	NTRK1/PDE6C/EPHB1/COL11A1/HTR2A/TNF/TRPA1	7
BP	GO:0032722	positive regulation of chemokine production	5/232	73/18986	0.0684931506849315	5.60521965044875	4.38463963403744	0.00199573871851132	0.00759232985796655	0.00379223998863033	EGR1/IL17RA/CLEC7A/TNF/HAVCR2	5
BP	GO:0060415	muscle tissue morphogenesis	5/232	73/18986	0.0684931506849315	5.60521965044875	4.38463963403744	0.00199573871851132	0.00759232985796655	0.00379223998863033	EDNRA/MYH7/COL3A1/COL11A1/TGFBR1	5
BP	GO:0002209	behavioral defense response	4/232	44/18986	0.0909090909090909	7.43965517241379	4.75640001753967	0.00201047639020169	0.00759625273834681	0.00379419940084331	PDE8B/EPHB2/HTR1A/BCL2	4
BP	GO:0014002	astrocyte development	4/232	44/18986	0.0909090909090909	7.43965517241379	4.75640001753967	0.00201047639020169	0.00759625273834681	0.00379419940084331	LAMB2/GRN/TNF/MAPT	4
BP	GO:0046627	negative regulation of insulin receptor signaling pathway	4/232	44/18986	0.0909090909090909	7.43965517241379	4.75640001753967	0.00201047639020169	0.00759625273834681	0.00379419940084331	PRKCD/PRKCQ/AHSG/PRKCZ	4
BP	GO:0010389	regulation of G2/M transition of mitotic cell cycle	6/232	107/18986	0.0560747663551402	4.58894618111505	4.14068009646009	0.00202104667767142	0.00759625273834681	0.00379419940084331	CDC7/CDK2/ATM/ATR/CDK1/BRD4	6
BP	GO:0014896	muscle hypertrophy	6/232	107/18986	0.0560747663551402	4.58894618111505	4.14068009646009	0.00202104667767142	0.00759625273834681	0.00379419940084331	PDE5A/PRKCA/NR4A3/LMNA/MYH7/PPP3CA	6
BP	GO:0032231	regulation of actin filament bundle assembly	6/232	107/18986	0.0560747663551402	4.58894618111505	4.14068009646009	0.00202104667767142	0.00759625273834681	0.00379419940084331	RHOA/APOA1/FLNA/BRAF/TGFBR1/NRP1	6
BP	GO:0032526	response to retinoic acid	6/232	107/18986	0.0560747663551402	4.58894618111505	4.14068009646009	0.00202104667767142	0.00759625273834681	0.00379419940084331	MMP2/ATM/ABCA1/COL1A1/TNF/SLC6A4	6
BP	GO:0055092	sterol homeostasis	6/232	107/18986	0.0560747663551402	4.58894618111505	4.14068009646009	0.00202104667767142	0.00759625273834681	0.00379419940084331	FABP4/APOA1/RORA/PLA2G10/ABCA1/HNF4A	6
BP	GO:0002716	negative regulation of natural killer cell mediated immunity	3/232	21/18986	0.142857142857143	11.6908866995074	5.45191766109597	0.00203585258141849	0.00759625273834681	0.00379419940084331	MICA/HLA-A/HAVCR2	3
BP	GO:0007413	axonal fasciculation	3/232	21/18986	0.142857142857143	11.6908866995074	5.45191766109597	0.00203585258141849	0.00759625273834681	0.00379419940084331	EPHB2/EPHB3/NRP1	3
BP	GO:0009310	amine catabolic process	3/232	21/18986	0.142857142857143	11.6908866995074	5.45191766109597	0.00203585258141849	0.00759625273834681	0.00379419940084331	MAOA/MAOB/SLC6A3	3
BP	GO:0010288	response to lead ion	3/232	21/18986	0.142857142857143	11.6908866995074	5.45191766109597	0.00203585258141849	0.00759625273834681	0.00379419940084331	MAP1LC3A/MAPT/PTGS2	3
BP	GO:0019370	leukotriene biosynthetic process	3/232	21/18986	0.142857142857143	11.6908866995074	5.45191766109597	0.00203585258141849	0.00759625273834681	0.00379419940084331	PLA2G5/LTA4H/ALOX5	3
BP	GO:0031954	positive regulation of protein autophosphorylation	3/232	21/18986	0.142857142857143	11.6908866995074	5.45191766109597	0.00203585258141849	0.00759625273834681	0.00379419940084331	VEGFA/PDGFA/INS	3
BP	GO:0038166	angiotensin-activated signaling pathway	3/232	21/18986	0.142857142857143	11.6908866995074	5.45191766109597	0.00203585258141849	0.00759625273834681	0.00379419940084331	PRKCA/PPP3CA/CA2	3
BP	GO:0044321	response to leptin	3/232	21/18986	0.142857142857143	11.6908866995074	5.45191766109597	0.00203585258141849	0.00759625273834681	0.00379419940084331	CCNA2/NR4A3/FGB	3
BP	GO:0048846	axon extension involved in axon guidance	3/232	21/18986	0.142857142857143	11.6908866995074	5.45191766109597	0.00203585258141849	0.00759625273834681	0.00379419940084331	VEGFA/NRP2/NRP1	3
BP	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	3/232	21/18986	0.142857142857143	11.6908866995074	5.45191766109597	0.00203585258141849	0.00759625273834681	0.00379419940084331	NTRK1/EPHB1/HTR2A	3
BP	GO:0071731	response to nitric oxide	3/232	21/18986	0.142857142857143	11.6908866995074	5.45191766109597	0.00203585258141849	0.00759625273834681	0.00379419940084331	CDK2/CCNA2/MMP3	3
BP	GO:0090200	positive regulation of release of cytochrome c from mitochondria	3/232	21/18986	0.142857142857143	11.6908866995074	5.45191766109597	0.00203585258141849	0.00759625273834681	0.00379419940084331	MMP9/PLAUR/TP53	3
BP	GO:0106030	neuron projection fasciculation	3/232	21/18986	0.142857142857143	11.6908866995074	5.45191766109597	0.00203585258141849	0.00759625273834681	0.00379419940084331	EPHB2/EPHB3/NRP1	3
BP	GO:1902284	neuron projection extension involved in neuron projection guidance	3/232	21/18986	0.142857142857143	11.6908866995074	5.45191766109597	0.00203585258141849	0.00759625273834681	0.00379419940084331	VEGFA/NRP2/NRP1	3
BP	GO:0050921	positive regulation of chemotaxis	7/232	145/18986	0.0482758620689655	3.95071343638526	3.9669926696665	0.0020623860710995	0.007688546503942	0.00384029857134024	VEGFA/KDR/PDGFRB/PDGFRA/CXCL8/NTRK3/NRP1	7
BP	GO:0048762	mesenchymal cell differentiation	10/232	274/18986	0.0364963503649635	2.98672287943619	3.68429848561709	0.0020653356031418	0.0076928353998557	0.00384244080210409	VEGFA/EDNRA/NRP2/FLNA/COL1A1/LAMA5/TGFBR1/NRP1/HGF/BCL2	10
BP	GO:0043583	ear development	9/232	229/18986	0.0393013100436681	3.21627014003915	3.75284894882616	0.00208135940589935	0.00774577268896922	0.00386888208013356	CCNA2/DDR1/KCNQ4/EDNRA/CDKN1B/EPHB2/COL2A1/COL11A1/BCL2	9
BP	GO:0033344	cholesterol efflux	5/232	74/18986	0.0675675675675676	5.5294734389562	4.34207364232128	0.00211941074306236	0.00787367535824034	0.00393276729404501	APOA1/PLA2G10/ABCA1/PON1/LIPA	5
BP	GO:0060411	cardiac septum morphogenesis	5/232	74/18986	0.0675675675675676	5.5294734389562	4.34207364232128	0.00211941074306236	0.00787367535824034	0.00393276729404501	NRP2/TP53/MDM2/TGFBR1/NRP1	5
BP	GO:0009582	detection of abiotic stimulus	7/232	146/18986	0.0479452054794521	3.92365375531412	3.94424836688595	0.00214422565997141	0.00795894871704665	0.00397535989042579	NTRK1/PDE6C/EPHB1/COL11A1/HTR2A/TNF/TRPA1	7
BP	GO:0015872	dopamine transport	4/232	45/18986	0.0888888888888889	7.27432950191571	4.68677888341536	0.00218573809796486	0.00806403460474353	0.00402784850894211	SNCA/KCNA2/HTR2A/SLC6A3	4
BP	GO:0042554	superoxide anion generation	4/232	45/18986	0.0888888888888889	7.27432950191571	4.68677888341536	0.00218573809796486	0.00806403460474353	0.00402784850894211	ITGB2/PRKCD/CLEC7A/MAPT	4
BP	GO:0060428	lung epithelium development	4/232	45/18986	0.0888888888888889	7.27432950191571	4.68677888341536	0.00218573809796486	0.00806403460474353	0.00402784850894211	THRA/LTA4H/COL6A1/THRB	4
BP	GO:0071402	cellular response to lipoprotein particle stimulus	4/232	45/18986	0.0888888888888889	7.27432950191571	4.68677888341536	0.00218573809796486	0.00806403460474353	0.00402784850894211	APOA1/ITGB1/ITGB2/ABCA1	4
BP	GO:1900077	negative regulation of cellular response to insulin stimulus	4/232	45/18986	0.0888888888888889	7.27432950191571	4.68677888341536	0.00218573809796486	0.00806403460474353	0.00402784850894211	PRKCD/PRKCQ/AHSG/PRKCZ	4
BP	GO:1903426	regulation of reactive oxygen species biosynthetic process	4/232	45/18986	0.0888888888888889	7.27432950191571	4.68677888341536	0.00218573809796486	0.00806403460474353	0.00402784850894211	SNCA/RHOA/INS/ALOX5	4
BP	GO:1990000	amyloid fibril formation	4/232	45/18986	0.0888888888888889	7.27432950191571	4.68677888341536	0.00218573809796486	0.00806403460474353	0.00402784850894211	SNCA/CDKN2A/MDM2/MAPT	4
BP	GO:0010952	positive regulation of peptidase activity	7/232	147/18986	0.0476190476190476	3.89696223316913	3.92170493895854	0.00222855338830026	0.00820076961133555	0.00409614532553784	SNCA/CDKN2A/COL4A3/GRN/CLEC7A/TNF/MAPT	7
BP	GO:0045598	regulation of fat cell differentiation	7/232	147/18986	0.0476190476190476	3.89696223316913	3.92170493895854	0.00222855338830026	0.00820076961133555	0.00409614532553784	VEGFA/RORA/HTR2A/INS/TNF/ALOX5/PTGS2	7
BP	GO:0046887	positive regulation of hormone secretion	7/232	147/18986	0.0476190476190476	3.89696223316913	3.92170493895854	0.00222855338830026	0.00820076961133555	0.00409614532553784	PRKCA/INHBA/F2/FGA/FGB/FGG/INS	7
BP	GO:0090559	regulation of membrane permeability	5/232	75/18986	0.0666666666666667	5.45574712643678	4.30027527800536	0.00224858048534727	0.00826735181027081	0.00412940200458852	HSPA1A/TP53/HSPA8/BCL2L1/BCL2	5
BP	GO:0006644	phospholipid metabolic process	12/232	374/18986	0.0320855614973262	2.62576064908722	3.53181725433795	0.00226242899257612	0.00830398830236521	0.00414770131098888	SNCA/PLAA/APOA1/PRKCD/PLA2G2A/ATM/PLA2G5/PLA2G10/HTR2A/PON1/PDGFA/ALOX15	12
BP	GO:0042176	regulation of protein catabolic process	12/232	374/18986	0.0320855614973262	2.62576064908722	3.53181725433795	0.00226242899257612	0.00830398830236521	0.00414770131098888	SNCA/HMGCR/DDB1/CDK2/CTSA/EEF1A1/HSPA1A/CDKN1B/FLNA/MDM2/INS/TNF	12
BP	GO:0071333	cellular response to glucose stimulus	7/232	148/18986	0.0472972972972973	3.87063140726934	3.89935908898947	0.00231541952093881	0.00849119543013237	0.00424120809604121	PDE8B/CPB2/ICAM1/SMARCA4/COL1A1/RAF1/PPP3CA	7
BP	GO:0072676	lymphocyte migration	6/232	110/18986	0.0545454545454545	4.46379310344828	4.05224447481645	0.00232406311339078	0.00851559029379517	0.00425339291667333	RHOA/ITGAL/ICAM1/ITGB7/KLRK1/PLEC	6
BP	GO:0009713	catechol-containing compound biosynthetic process	3/232	22/18986	0.136363636363636	11.1594827586207	5.30298382035586	0.00233619709675914	0.00852353138715194	0.00425735935811415	NR4A2/SNCA/SLC6A3	3
BP	GO:0021554	optic nerve development	3/232	22/18986	0.136363636363636	11.1594827586207	5.30298382035586	0.00233619709675914	0.00852353138715194	0.00425735935811415	KCNA2/EPHB2/EPHB1	3
BP	GO:0042423	catecholamine biosynthetic process	3/232	22/18986	0.136363636363636	11.1594827586207	5.30298382035586	0.00233619709675914	0.00852353138715194	0.00425735935811415	NR4A2/SNCA/SLC6A3	3
BP	GO:0060193	positive regulation of lipase activity	3/232	22/18986	0.136363636363636	11.1594827586207	5.30298382035586	0.00233619709675914	0.00852353138715194	0.00425735935811415	PLAA/RHOA/PLA2G5	3
BP	GO:0071498	cellular response to fluid shear stress	3/232	22/18986	0.136363636363636	11.1594827586207	5.30298382035586	0.00233619709675914	0.00852353138715194	0.00425735935811415	MMP2/PTGS2/PLEC	3
BP	GO:0001504	neurotransmitter uptake	4/232	46/18986	0.0869565217391304	7.11619190404798	4.61925959304174	0.00237125811523874	0.00863671184051181	0.00431389107488515	SNCA/ITGB1/SLC6A4/SLC6A3	4
BP	GO:1903573	negative regulation of response to endoplasmic reticulum stress	4/232	46/18986	0.0869565217391304	7.11619190404798	4.61925959304174	0.00237125811523874	0.00863671184051181	0.00431389107488515	HSPA1A/HSPA5/ALOX5/BCL2L1	4
BP	GO:0050709	negative regulation of protein secretion	5/232	76/18986	0.0657894736842105	5.3839609800363	4.25921976418845	0.00238338954264671	0.00866613408533787	0.00432858698713764	HMGCR/PDE8B/IL12B/INS/PPP3CA	5
BP	GO:0072678	T cell migration	5/232	76/18986	0.0657894736842105	5.3839609800363	4.25921976418845	0.00238338954264671	0.00866613408533787	0.00432858698713764	RHOA/ITGAL/ICAM1/ITGB7/PLEC	5
BP	GO:0051348	negative regulation of transferase activity	8/232	190/18986	0.0421052631578947	3.44573502722323	3.76838983035443	0.00238672852896498	0.00867090160565357	0.00433096828267222	SNCA/PRKCD/PRKCH/CDKN1B/CDKN2A/EPHB2/PPIA/MAPT	8
BP	GO:0021537	telencephalon development	10/232	281/18986	0.0355871886120996	2.9123205301264	3.59200827551271	0.00247990384567778	0.00900175623439574	0.00449622455802003	NTRK2/RHOA/KCNA2/INHBA/EPHB2/EPHB3/FLNA/COL3A1/LAMB1/SRD5A1	10
BP	GO:0050714	positive regulation of protein secretion	7/232	150/18986	0.0466666666666667	3.81902298850575	3.85524731570603	0.00249696988700555	0.00905601631623049	0.00452332654857754	PRKCA/F2/FGA/FGB/FGG/PPIA/INS	7
BP	GO:0006801	superoxide metabolic process	5/232	77/18986	0.0649350649350649	5.31403940886699	4.21888344290116	0.00252397980862292	0.0091230242279557	0.00455679586394617	SHC1/ITGB2/PRKCD/CLEC7A/MAPT	5
BP	GO:0030239	myofibril assembly	5/232	77/18986	0.0649350649350649	5.31403940886699	4.21888344290116	0.00252397980862292	0.0091230242279557	0.00455679586394617	PDGFRB/PDGFRA/ITGB1/MYH7/PLEC	5
BP	GO:0046470	phosphatidylcholine metabolic process	5/232	77/18986	0.0649350649350649	5.31403940886699	4.21888344290116	0.00252397980862292	0.0091230242279557	0.00455679586394617	APOA1/PLA2G2A/PLA2G5/PLA2G10/PON1	5
BP	GO:1904377	positive regulation of protein localization to cell periphery	5/232	77/18986	0.0649350649350649	5.31403940886699	4.21888344290116	0.00252397980862292	0.0091230242279557	0.00455679586394617	SNCA/ITGB1/PRKCH/EPHB2/TNF	5
BP	GO:0007040	lysosome organization	6/232	112/18986	0.0535714285714286	4.38408251231527	3.99503250278743	0.00254428025607103	0.00918087964131621	0.00458569366161947	HEXA/PLA2G5/ABCA1/HSPA8/GRN/LIPA	6
BP	GO:0080171	lytic vacuole organization	6/232	112/18986	0.0535714285714286	4.38408251231527	3.99503250278743	0.00254428025607103	0.00918087964131621	0.00458569366161947	HEXA/PLA2G5/ABCA1/HSPA8/GRN/LIPA	6
BP	GO:0003009	skeletal muscle contraction	4/232	47/18986	0.0851063829787234	6.96478356566398	4.55373164850722	0.00256733228570181	0.00923289558760381	0.00461167474453452	CHUK/MYH7/NR4A1/TNF	4
BP	GO:0045840	positive regulation of mitotic nuclear division	4/232	47/18986	0.0851063829787234	6.96478356566398	4.55373164850722	0.00256733228570181	0.00923289558760381	0.00461167474453452	PDGFRB/IGF2/INS/TNF	4
BP	GO:0050919	negative chemotaxis	4/232	47/18986	0.0851063829787234	6.96478356566398	4.55373164850722	0.00256733228570181	0.00923289558760381	0.00461167474453452	RHOA/APOA1/NRP2/PDGFA	4
BP	GO:0055010	ventricular cardiac muscle tissue morphogenesis	4/232	47/18986	0.0851063829787234	6.96478356566398	4.55373164850722	0.00256733228570181	0.00923289558760381	0.00461167474453452	EDNRA/MYH7/COL11A1/TGFBR1	4
BP	GO:0051783	regulation of nuclear division	7/232	151/18986	0.0463576158940397	3.79373144553551	3.83347517219734	0.00259175644957583	0.0093050802505342	0.00464772975932596	PDE3A/PDGFRB/ATM/IGF2/INS/TNF/NPR2	7
BP	GO:0071331	cellular response to hexose stimulus	7/232	151/18986	0.0463576158940397	3.79373144553551	3.83347517219734	0.00259175644957583	0.0093050802505342	0.00464772975932596	PDE8B/CPB2/ICAM1/SMARCA4/COL1A1/RAF1/PPP3CA	7
BP	GO:0006109	regulation of carbohydrate metabolic process	8/232	193/18986	0.0414507772020725	3.39217437913168	3.71514500796105	0.00262902179218729	0.00943095401291346	0.00471060156865772	SNCA/DDB1/RORA/TP53/IGF2/AP2A1/HTR2A/INS	8
BP	GO:0002223	stimulatory C-type lectin receptor signaling pathway	3/232	23/18986	0.130434782608696	10.674287856072	5.16335206289025	0.00266258656862151	0.00949559646991291	0.00474288937951191	IKBKB/KLRK1/CLEC7A	3
BP	GO:0046479	glycosphingolipid catabolic process	3/232	23/18986	0.130434782608696	10.674287856072	5.16335206289025	0.00266258656862151	0.00949559646991291	0.00474288937951191	HEXA/PRKCD/GLA	3
BP	GO:0060008	Sertoli cell differentiation	3/232	23/18986	0.130434782608696	10.674287856072	5.16335206289025	0.00266258656862151	0.00949559646991291	0.00474288937951191	NTRK1/INHBA/FLNA	3
BP	GO:0060352	cell adhesion molecule production	3/232	23/18986	0.130434782608696	10.674287856072	5.16335206289025	0.00266258656862151	0.00949559646991291	0.00474288937951191	APOA1/CXCL8/PPIA	3
BP	GO:0060444	branching involved in mammary gland duct morphogenesis	3/232	23/18986	0.130434782608696	10.674287856072	5.16335206289025	0.00266258656862151	0.00949559646991291	0.00474288937951191	DDR1/ESR1/AR	3
BP	GO:1990840	response to lectin	3/232	23/18986	0.130434782608696	10.674287856072	5.16335206289025	0.00266258656862151	0.00949559646991291	0.00474288937951191	IKBKB/KLRK1/CLEC7A	3
BP	GO:1990858	cellular response to lectin	3/232	23/18986	0.130434782608696	10.674287856072	5.16335206289025	0.00266258656862151	0.00949559646991291	0.00474288937951191	IKBKB/KLRK1/CLEC7A	3
BP	GO:0010827	regulation of D-glucose transmembrane transport	5/232	78/18986	0.0641025641025641	5.24591069849691	4.17924371069623	0.00267049340320062	0.00950002478542915	0.0047451012480025	NR4A3/EDNRA/BRAF/INS/TNF	5
BP	GO:0019226	transmission of nerve impulse	5/232	78/18986	0.0641025641025641	5.24591069849691	4.17924371069623	0.00267049340320062	0.00950002478542915	0.0047451012480025	NTRK2/KCNA2/COL6A1/NPR2/PLEC	5
BP	GO:0050772	positive regulation of axonogenesis	5/232	78/18986	0.0641025641025641	5.24591069849691	4.17924371069623	0.00267049340320062	0.00950002478542915	0.0047451012480025	VEGFA/NTRK2/BRAF/NRP1/MAPT	5
BP	GO:0002687	positive regulation of leukocyte migration	7/232	152/18986	0.0460526315789474	3.76877268602541	3.811888161939	0.00268928605507708	0.00955098602284849	0.00477055552172704	VEGFA/RHOA/ICAM1/IL1R1/CXCL8/MMP14/TNF	7
BP	GO:0007093	mitotic cell cycle checkpoint signaling	7/232	152/18986	0.0460526315789474	3.76877268602541	3.811888161939	0.00268928605507708	0.00955098602284849	0.00477055552172704	CDK2/ATM/ATR/CDK1/CDKN1B/TP53/MDM2	7
BP	GO:0050767	regulation of neurogenesis	12/232	383/18986	0.031331592689295	2.56405870171964	3.43924631101522	0.00274709988205059	0.00974821501713554	0.00486906805912265	VEGFA/NTRK2/ITGB1/PRKCH/TP53/EPHB2/F2/BRAF/NRP1/TNF/PPP3CA/MAPT	12
BP	GO:0006911	phagocytosis, engulfment	4/232	48/18986	0.0833333333333333	6.81968390804598	4.49009259167156	0.0027742537401874	0.00982354430654095	0.00490669376150155	MYH9/ITGB2/ABCA1/ALOX15	4
BP	GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	4/232	48/18986	0.0833333333333333	6.81968390804598	4.49009259167156	0.0027742537401874	0.00982354430654095	0.00490669376150155	PRKCQ/BRD4/IL12B/PRKCZ	4
BP	GO:0042752	regulation of circadian rhythm	6/232	114/18986	0.0526315789473684	4.30716878402904	3.93914673816596	0.00277981492303895	0.00982354430654095	0.00490669376150155	DDB1/KCNA2/RORA/CDK1/TP53/HNF4A	6
BP	GO:0090277	positive regulation of peptide hormone secretion	6/232	114/18986	0.0526315789473684	4.30716878402904	3.93914673816596	0.00277981492303895	0.00982354430654095	0.00490669376150155	PRKCA/F2/FGA/FGB/FGG/INS	6
BP	GO:2001056	positive regulation of cysteine-type endopeptidase activity	6/232	114/18986	0.0526315789473684	4.30716878402904	3.93914673816596	0.00277981492303895	0.00982354430654095	0.00490669376150155	SNCA/CDKN2A/COL4A3/CLEC7A/TNF/MAPT	6
BP	GO:0071326	cellular response to monosaccharide stimulus	7/232	153/18986	0.0457516339869281	3.74414018480956	3.79048334866661	0.00278961070881954	0.00985002096689706	0.0049199184042721	PDE8B/CPB2/ICAM1/SMARCA4/COL1A1/RAF1/PPP3CA	7
BP	GO:1901988	negative regulation of cell cycle phase transition	10/232	287/18986	0.0348432055749129	2.85143578036766	3.5151409776433	0.00288619185430907	0.0101797937192032	0.0050846343006901	CDK2/INHBA/ATM/ATR/CDK1/CDKN1B/TP53/MDM2/BRD4/BCL2	10
BP	GO:0002695	negative regulation of leukocyte activation	8/232	196/18986	0.0408163265306122	3.3402533427164	3.66294044163725	0.00289014723459137	0.0101797937192032	0.0050846343006901	PDE5A/INHBA/ATM/PLA2G5/CDKN2A/MICA/GRN/HAVCR2	8
BP	GO:0046890	regulation of lipid biosynthetic process	8/232	196/18986	0.0408163265306122	3.3402533427164	3.66294044163725	0.00289014723459137	0.0101797937192032	0.0050846343006901	PDE8B/EGR1/PRKCD/HTR2A/PDGFA/INS/TNF/PTGS2	8
BP	GO:0048477	oogenesis	6/232	115/18986	0.0521739130434783	4.26971514242879	3.91168359587278	0.00290352994538085	0.0102185136184761	0.00510397423363894	PDE5A/PDE3A/EDNRA/ATM/NPR2/BCL2	6
BP	GO:0006091	generation of precursor metabolites and energy	14/232	490/18986	0.0285714285714286	2.33817733990148	3.33791397987605	0.00292078386923992	0.0102707827507154	0.00513008177864249	SNCA/NR4A3/RHOA/CDK1/CYP1A2/TP53/ALDOA/IGF2/COL6A1/HTR2A/INS/LIPA/TNF/PLEC	14
BP	GO:0022898	regulation of transmembrane transporter activity	8/232	197/18986	0.0406091370558376	3.32329774199195	3.64576345735853	0.00298154218792474	0.0104450033253895	0.00521710200069305	SNCA/CRBN/ITGB1/MMP9/EDNRA/EPHB2/INS/BCL2	8
BP	GO:0090049	regulation of cell migration involved in sprouting angiogenesis	5/232	80/18986	0.0625	5.11476293103448	4.10196851691249	0.00298185977325189	0.0104450033253895	0.00521710200069305	VEGFA/KDR/RHOA/NRP1/PTGS2	5
BP	GO:1904019	epithelial cell apoptotic process	5/232	80/18986	0.0625	5.11476293103448	4.10196851691249	0.00298185977325189	0.0104450033253895	0.00521710200069305	EDNRA/ESR1/CDKN1B/BCL2L1/BCL2	5
BP	GO:0006509	membrane protein ectodomain proteolysis	4/232	49/18986	0.0816326530612245	6.68050668543279	4.42824726505146	0.00299231269261042	0.0104450033253895	0.00521710200069305	MYH9/PRKCQ/ERAP1/TNF	4
BP	GO:0042088	T-helper 1 type immune response	4/232	49/18986	0.0816326530612245	6.68050668543279	4.42824726505146	0.00299231269261042	0.0104450033253895	0.00521710200069305	IL1R1/IL18R1/IL12B/HAVCR2	4
BP	GO:0042596	fear response	4/232	49/18986	0.0816326530612245	6.68050668543279	4.42824726505146	0.00299231269261042	0.0104450033253895	0.00521710200069305	PDE8B/EPHB2/HTR1A/BCL2	4
BP	GO:0048546	digestive tract morphogenesis	4/232	49/18986	0.0816326530612245	6.68050668543279	4.42824726505146	0.00299231269261042	0.0104450033253895	0.00521710200069305	PDGFRA/EPHB3/NPR2/BCL2	4
BP	GO:0050432	catecholamine secretion	4/232	49/18986	0.0816326530612245	6.68050668543279	4.42824726505146	0.00299231269261042	0.0104450033253895	0.00521710200069305	SNCA/KCNA2/HTR2A/ADORA3	4
BP	GO:1905710	positive regulation of membrane permeability	4/232	49/18986	0.0816326530612245	6.68050668543279	4.42824726505146	0.00299231269261042	0.0104450033253895	0.00521710200069305	HSPA1A/TP53/HSPA8/BCL2L1	4
BP	GO:0006469	negative regulation of protein kinase activity	7/232	155/18986	0.0451612903225806	3.69582869855395	3.74820889567738	0.00299885476271588	0.0104500167450855	0.0052196061187973	SNCA/PRKCD/PRKCH/CDKN1B/CDKN2A/EPHB2/PPIA	7
BP	GO:0007263	nitric oxide mediated signal transduction	3/232	24/18986	0.125	10.229525862069	5.03205382852394	0.00301574384084084	0.0104500167450855	0.0052196061187973	VEGFA/PDE5A/INS	3
BP	GO:0015874	norepinephrine transport	3/232	24/18986	0.125	10.229525862069	5.03205382852394	0.00301574384084084	0.0104500167450855	0.0052196061187973	SNCA/SLC6A3/ADORA3	3
BP	GO:0030539	male genitalia development	3/232	24/18986	0.125	10.229525862069	5.03205382852394	0.00301574384084084	0.0104500167450855	0.0052196061187973	PDGFRA/AR/SRD5A1	3
BP	GO:0045822	negative regulation of heart contraction	3/232	24/18986	0.125	10.229525862069	5.03205382852394	0.00301574384084084	0.0104500167450855	0.0052196061187973	PDE5A/PDE4D/TNF	3
BP	GO:0046628	positive regulation of insulin receptor signaling pathway	3/232	24/18986	0.125	10.229525862069	5.03205382852394	0.00301574384084084	0.0104500167450855	0.0052196061187973	IGF2/INS/PRKCZ	3
BP	GO:0046641	positive regulation of alpha-beta T cell proliferation	3/232	24/18986	0.125	10.229525862069	5.03205382852394	0.00301574384084084	0.0104500167450855	0.0052196061187973	PRKCQ/IL12B/HLA-A	3
BP	GO:1903429	regulation of cell maturation	3/232	24/18986	0.125	10.229525862069	5.03205382852394	0.00301574384084084	0.0104500167450855	0.0052196061187973	CLEC7A/NPR2/BCL2	3
BP	GO:2000810	regulation of bicellular tight junction assembly	3/232	24/18986	0.125	10.229525862069	5.03205382852394	0.00301574384084084	0.0104500167450855	0.0052196061187973	PRKCH/IKBKB/TNF	3
BP	GO:0002062	chondrocyte differentiation	6/232	116/18986	0.0517241379310345	4.23290725326992	3.88453132068855	0.00303131941456636	0.0104785139989376	0.0052338400137473	COL2A1/COL3A1/COL11A1/COL27A1/TGFBR1/NPR2	6
BP	GO:0002793	positive regulation of peptide secretion	6/232	116/18986	0.0517241379310345	4.23290725326992	3.88453132068855	0.00303131941456636	0.0104785139989376	0.0052338400137473	PRKCA/F2/FGA/FGB/FGG/INS	6
BP	GO:0060840	artery development	6/232	116/18986	0.0517241379310345	4.23290725326992	3.88453132068855	0.00303131941456636	0.0104785139989376	0.0052338400137473	VEGFA/PDGFRB/EDNRA/COL3A1/TGFBR1/NRP1	6
BP	GO:0031960	response to corticosteroid	7/232	156/18986	0.0448717948717949	3.67213748894783	3.7273337054491	0.00310787972299709	0.010734486022242	0.00536169369778173	INHBA/MAOB/CYP1B1/TNF/BCL2/PTGS2/SRD5A1	7
BP	GO:0048872	homeostasis of number of cells	11/232	339/18986	0.0324483775811209	2.65545214118604	3.42069482746059	0.00313202126572831	0.0108091387669526	0.00539898147756063	VEGFA/PDE4B/INHBA/PLA2G2A/THRA/HSPA1A/XIAP/PLA2G10/COL6A1/LIPA/BCL2	11
BP	GO:0021536	diencephalon development	5/232	81/18986	0.0617283950617284	5.05161770966369	4.06429260196985	0.00314699729855751	0.010817170778643	0.00540299333116702	NR4A2/NRP2/NRP1/SRD5A1/SLC6A3	5
BP	GO:0032088	negative regulation of NF-kappaB transcription factor activity	5/232	81/18986	0.0617283950617284	5.05161770966369	4.06429260196985	0.00314699729855751	0.010817170778643	0.00540299333116702	CHUK/CYP1B1/CDKN2A/HAVCR2/ADORA3	5
BP	GO:0042093	T-helper cell differentiation	5/232	81/18986	0.0617283950617284	5.05161770966369	4.06429260196985	0.00314699729855751	0.010817170778643	0.00540299333116702	RORA/IL18R1/BRD4/IL12B/PRKCZ	5
BP	GO:0045921	positive regulation of exocytosis	5/232	81/18986	0.0617283950617284	5.05161770966369	4.06429260196985	0.00314699729855751	0.010817170778643	0.00540299333116702	SNCA/ITGB2/FGA/FGB/FGG	5
BP	GO:0048644	muscle organ morphogenesis	5/232	81/18986	0.0617283950617284	5.05161770966369	4.06429260196985	0.00314699729855751	0.010817170778643	0.00540299333116702	EDNRA/MYH7/COL3A1/COL11A1/TGFBR1	5
BP	GO:0043368	positive T cell selection	4/232	50/18986	0.08	6.54689655172414	4.36810715420887	0.00322179624574567	0.0110476349212578	0.0055181062614426	BRD4/IL12B/BRAF/BCL2	4
BP	GO:0051489	regulation of filopodium assembly	4/232	50/18986	0.08	6.54689655172414	4.36810715420887	0.00322179624574567	0.0110476349212578	0.0055181062614426	PRKCD/EPHB2/TGFBR1/NRP1	4
BP	GO:0060976	coronary vasculature development	4/232	50/18986	0.08	6.54689655172414	4.36810715420887	0.00322179624574567	0.0110476349212578	0.0055181062614426	VEGFA/PDGFRB/TGFBR1/NRP1	4
BP	GO:0046822	regulation of nucleocytoplasmic transport	6/232	118/18986	0.0508474576271186	4.16116306253653	3.83113367793418	0.00329945159332448	0.0113048517732816	0.00564658171630851	PRKCD/CDK1/CDKN2A/FLNA/MDM2/PTGS2	6
BP	GO:0008544	epidermis development	12/232	393/18986	0.0305343511450382	2.4988154777573	3.33942771459225	0.00338143472373401	0.0115260380475454	0.00575706050870702	INHBA/PRKCH/PLA2G10/COL6A1/LAMA3/LAMA5/LAMB3/PDGFA/TNF/PPP3CA/BCL2/PLEC	12
BP	GO:0002082	regulation of oxidative phosphorylation	3/232	25/18986	0.12	9.82034482758621	4.90825690909942	0.00339635358744322	0.0115260380475454	0.00575706050870702	SNCA/RHOA/TNF	3
BP	GO:0006706	steroid catabolic process	3/232	25/18986	0.12	9.82034482758621	4.90825690909942	0.00339635358744322	0.0115260380475454	0.00575706050870702	CYP3A4/CYP1A2/SRD5A1	3
BP	GO:0007350	blastoderm segmentation	3/232	25/18986	0.12	9.82034482758621	4.90825690909942	0.00339635358744322	0.0115260380475454	0.00575706050870702	NRP2/LAMA5/NRP1	3
BP	GO:0009110	vitamin biosynthetic process	3/232	25/18986	0.12	9.82034482758621	4.90825690909942	0.00339635358744322	0.0115260380475454	0.00575706050870702	CYP3A4/CYP2R1/TNF	3
BP	GO:0014059	regulation of dopamine secretion	3/232	25/18986	0.12	9.82034482758621	4.90825690909942	0.00339635358744322	0.0115260380475454	0.00575706050870702	SNCA/KCNA2/HTR2A	3
BP	GO:0014829	vascular associated smooth muscle contraction	3/232	25/18986	0.12	9.82034482758621	4.90825690909942	0.00339635358744322	0.0115260380475454	0.00575706050870702	RHOA/EDNRA/HTR2A	3
BP	GO:0038095	Fc-epsilon receptor signaling pathway	3/232	25/18986	0.12	9.82034482758621	4.90825690909942	0.00339635358744322	0.0115260380475454	0.00575706050870702	NR4A3/PRKCQ/IKBKB	3
BP	GO:0045762	positive regulation of adenylate cyclase activity	3/232	25/18986	0.12	9.82034482758621	4.90825690909942	0.00339635358744322	0.0115260380475454	0.00575706050870702	EDNRA/RAF1/ADORA3	3
BP	GO:0046514	ceramide catabolic process	3/232	25/18986	0.12	9.82034482758621	4.90825690909942	0.00339635358744322	0.0115260380475454	0.00575706050870702	HEXA/PRKCD/GLA	3
BP	GO:0050961	detection of temperature stimulus involved in sensory perception	3/232	25/18986	0.12	9.82034482758621	4.90825690909942	0.00339635358744322	0.0115260380475454	0.00575706050870702	NTRK1/EPHB1/HTR2A	3
BP	GO:0071280	cellular response to copper ion	3/232	25/18986	0.12	9.82034482758621	4.90825690909942	0.00339635358744322	0.0115260380475454	0.00575706050870702	SNCA/CYP1A1/MAP1LC3A	3
BP	GO:0050769	positive regulation of neurogenesis	9/232	247/18986	0.0364372469635627	2.98188608125087	3.48703491585579	0.00344926491923325	0.0116963178387322	0.0058421123762463	VEGFA/NTRK2/ITGB1/PRKCH/EPHB2/BRAF/NRP1/TNF/MAPT	9
BP	GO:0001914	regulation of T cell mediated cytotoxicity	4/232	51/18986	0.0784313725490196	6.4185260311021	4.30958980122145	0.00346298820657535	0.0116964751748153	0.00584219096295118	IL12B/HSPA8/MICA/HLA-A	4
BP	GO:0006636	unsaturated fatty acid biosynthetic process	4/232	51/18986	0.0784313725490196	6.4185260311021	4.30958980122145	0.00346298820657535	0.0116964751748153	0.00584219096295118	PLA2G10/PTGS1/ALOX15/PTGS2	4
BP	GO:0008542	visual learning	4/232	51/18986	0.0784313725490196	6.4185260311021	4.30958980122145	0.00346298820657535	0.0116964751748153	0.00584219096295118	HMGCR/PDE8B/ITGB1/BRAF	4
BP	GO:0042311	vasodilation	4/232	51/18986	0.0784313725490196	6.4185260311021	4.30958980122145	0.00346298820657535	0.0116964751748153	0.00584219096295118	VEGFA/ITGA1/INS/TNF	4
BP	GO:0046686	response to cadmium ion	4/232	51/18986	0.0784313725490196	6.4185260311021	4.30958980122145	0.00346298820657535	0.0116964751748153	0.00584219096295118	CDK1/CDKN1B/CYP1A2/HSPA8	4
BP	GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	5/232	83/18986	0.0602409638554217	4.92989198171998	3.99076936533331	0.0034968926530721	0.0117923603978993	0.00589008400554814	RORA/IL18R1/BRD4/IL12B/PRKCZ	5
BP	GO:0006289	nucleotide-excision repair	5/232	83/18986	0.0602409638554217	4.92989198171998	3.99076936533331	0.0034968926530721	0.0117923603978993	0.00589008400554814	DDB1/RPA1/SMARCA4/TP53/POLD3	5
BP	GO:1903320	regulation of protein modification by small protein conjugation or removal	9/232	248/18986	0.0362903225806452	2.96986234705228	3.47298125612063	0.00354208798821778	0.0119353571612445	0.00596150846343484	PLAA/SKP2/EGR1/HSPA1A/XIAP/HSPA5/CDKN2A/PPIA/TGFBR1	9
BP	GO:0000075	cell cycle checkpoint signaling	8/232	203/18986	0.0394088669950739	3.22507219296756	3.54496525872995	0.00357819623307005	0.0120475331437854	0.0060175384640689	CDK2/ATM/ATR/CDK1/CDKN1B/TP53/MDM2/BRD4	8
BP	GO:0002287	alpha-beta T cell activation involved in immune response	5/232	84/18986	0.0595238095238095	4.87120279146141	3.95488648989309	0.0036819347524583	0.0123675985872048	0.00617740572434604	RORA/IL18R1/BRD4/IL12B/PRKCZ	5
BP	GO:0002293	alpha-beta T cell differentiation involved in immune response	5/232	84/18986	0.0595238095238095	4.87120279146141	3.95488648989309	0.0036819347524583	0.0123675985872048	0.00617740572434604	RORA/IL18R1/BRD4/IL12B/PRKCZ	5
BP	GO:0034248	regulation of amide metabolic process	5/232	84/18986	0.0595238095238095	4.87120279146141	3.95488648989309	0.0036819347524583	0.0123675985872048	0.00617740572434604	NTRK2/SNCA/PRKCD/TP53/TNF	5
BP	GO:0009299	mRNA transcription	4/232	52/18986	0.0769230769230769	6.29509283819629	4.25261828032248	0.00371616891092936	0.0124337545094945	0.00621044948544245	THRA/TP53/FLNA/THRB	4
BP	GO:0010171	body morphogenesis	4/232	52/18986	0.0769230769230769	6.29509283819629	4.25261828032248	0.00371616891092936	0.0124337545094945	0.00621044948544245	MMP2/PDGFRA/COL1A1/BRAF	4
BP	GO:0032964	collagen biosynthetic process	4/232	52/18986	0.0769230769230769	6.29509283819629	4.25261828032248	0.00371616891092936	0.0124337545094945	0.00621044948544245	INHBA/F2/COL1A1/COL5A1	4
BP	GO:0042461	photoreceptor cell development	4/232	52/18986	0.0769230769230769	6.29509283819629	4.25261828032248	0.00371616891092936	0.0124337545094945	0.00621044948544245	VEGFA/NTRK2/PDE6C/THRB	4
BP	GO:0046466	membrane lipid catabolic process	4/232	52/18986	0.0769230769230769	6.29509283819629	4.25261828032248	0.00371616891092936	0.0124337545094945	0.00621044948544245	HEXA/PRKCD/CYP1B1/GLA	4
BP	GO:0007265	Ras protein signal transduction	6/232	121/18986	0.0495867768595041	4.05799373040752	3.75321296965558	0.00373427738361321	0.0124845739580376	0.00623583293802823	NTRK1/CDK2/CCNA2/TP53/CDKN2A/EPHB2	6
BP	GO:0031396	regulation of protein ubiquitination	8/232	205/18986	0.0390243902439024	3.19360807401177	3.51219764604518	0.00379637402833943	0.0125737641375107	0.00628038191989788	PLAA/SKP2/HSPA1A/XIAP/HSPA5/CDKN2A/PPIA/TGFBR1	8
BP	GO:0001911	negative regulation of leukocyte mediated cytotoxicity	3/232	26/18986	0.115384615384615	9.44263925729443	4.79124167523437	0.00380506332879767	0.0125737641375107	0.00628038191989788	MICA/HLA-A/HAVCR2	3
BP	GO:0019377	glycolipid catabolic process	3/232	26/18986	0.115384615384615	9.44263925729443	4.79124167523437	0.00380506332879767	0.0125737641375107	0.00628038191989788	HEXA/PRKCD/GLA	3
BP	GO:0022038	corpus callosum development	3/232	26/18986	0.115384615384615	9.44263925729443	4.79124167523437	0.00380506332879767	0.0125737641375107	0.00628038191989788	KCNA2/EPHB2/EPHB3	3
BP	GO:0034138	toll-like receptor 3 signaling pathway	3/232	26/18986	0.115384615384615	9.44263925729443	4.79124167523437	0.00380506332879767	0.0125737641375107	0.00628038191989788	IKBKB/TNF/HAVCR2	3
BP	GO:0035988	chondrocyte proliferation	3/232	26/18986	0.115384615384615	9.44263925729443	4.79124167523437	0.00380506332879767	0.0125737641375107	0.00628038191989788	MMP14/LTF/NPR2	3
BP	GO:0036315	cellular response to sterol	3/232	26/18986	0.115384615384615	9.44263925729443	4.79124167523437	0.00380506332879767	0.0125737641375107	0.00628038191989788	INHBA/RORA/ABCA1	3
BP	GO:0045624	positive regulation of T-helper cell differentiation	3/232	26/18986	0.115384615384615	9.44263925729443	4.79124167523437	0.00380506332879767	0.0125737641375107	0.00628038191989788	BRD4/IL12B/PRKCZ	3
BP	GO:0048143	astrocyte activation	3/232	26/18986	0.115384615384615	9.44263925729443	4.79124167523437	0.00380506332879767	0.0125737641375107	0.00628038191989788	GRN/TNF/MAPT	3
BP	GO:0051894	positive regulation of focal adhesion assembly	3/232	26/18986	0.115384615384615	9.44263925729443	4.79124167523437	0.00380506332879767	0.0125737641375107	0.00628038191989788	VEGFA/KDR/NRP1	3
BP	GO:0060740	prostate gland epithelium morphogenesis	3/232	26/18986	0.115384615384615	9.44263925729443	4.79124167523437	0.00380506332879767	0.0125737641375107	0.00628038191989788	MMP2/ESR1/AR	3
BP	GO:0072576	liver morphogenesis	3/232	26/18986	0.115384615384615	9.44263925729443	4.79124167523437	0.00380506332879767	0.0125737641375107	0.00628038191989788	CPB2/LIPA/TNF	3
BP	GO:0098581	detection of external biotic stimulus	3/232	26/18986	0.115384615384615	9.44263925729443	4.79124167523437	0.00380506332879767	0.0125737641375107	0.00628038191989788	NR4A1/HLA-A/CLEC7A	3
BP	GO:1900078	positive regulation of cellular response to insulin stimulus	3/232	26/18986	0.115384615384615	9.44263925729443	4.79124167523437	0.00380506332879767	0.0125737641375107	0.00628038191989788	IGF2/INS/PRKCZ	3
BP	GO:1903523	negative regulation of blood circulation	3/232	26/18986	0.115384615384615	9.44263925729443	4.79124167523437	0.00380506332879767	0.0125737641375107	0.00628038191989788	PDE5A/PDE4D/TNF	3
BP	GO:0000723	telomere maintenance	7/232	162/18986	0.0432098765432099	3.53613239676458	3.6055855896461	0.00382703988016737	0.0126366197124291	0.00631177721346035	CDK2/PRKCQ/ATM/ATR/RPA1/TP53/LMNA	7
BP	GO:0048863	stem cell differentiation	9/232	251/18986	0.0358565737051793	2.93436598433851	3.43123920863477	0.00383238516922644	0.0126445053885897	0.00631571597495163	PDGFRA/ITGB1/EDNRA/ESR1/NRP2/TP53/LAMA5/NRP1/BCL2	9
BP	GO:0030518	nuclear receptor-mediated steroid hormone signaling pathway	6/232	122/18986	0.0491803278688525	4.02473148671566	3.72779641258954	0.00388825349777842	0.012789363043462	0.00638806991659306	SKP2/RHOA/ESR1/ESR2/SMARCA4/AR	6
BP	GO:0043500	muscle adaptation	6/232	122/18986	0.0491803278688525	4.02473148671566	3.72779641258954	0.00388825349777842	0.012789363043462	0.00638806991659306	PDE5A/PRKCA/NR4A3/LMNA/MYH7/PPP3CA	6
BP	GO:0046634	regulation of alpha-beta T cell activation	6/232	122/18986	0.0491803278688525	4.02473148671566	3.72779641258954	0.00388825349777842	0.012789363043462	0.00638806991659306	RHOA/PRKCQ/BRD4/IL12B/HLA-A/PRKCZ	6
BP	GO:0071887	leukocyte apoptotic process	6/232	122/18986	0.0491803278688525	4.02473148671566	3.72779641258954	0.00388825349777842	0.012789363043462	0.00638806991659306	PRKCQ/TP53/CDKN2A/LIPA/BCL2L1/BCL2	6
BP	GO:0030073	insulin secretion	8/232	206/18986	0.0388349514563107	3.17810512219618	3.49596430676994	0.00390925127394695	0.0128485460779379	0.00641763083849538	PDE8B/PRKCA/F2/RAF1/TNF/PPP3CA/HNF4A/ALOX5	8
BP	GO:0001754	eye photoreceptor cell differentiation	4/232	53/18986	0.0754716981132075	6.17631750162654	4.19712072806371	0.00398161505714899	0.0130562775953751	0.00652138920806854	VEGFA/NTRK2/PDE6C/THRB	4
BP	GO:0030520	estrogen receptor signaling pathway	4/232	53/18986	0.0754716981132075	6.17631750162654	4.19712072806371	0.00398161505714899	0.0130562775953751	0.00652138920806854	SKP2/ESR1/ESR2/AR	4
BP	GO:0101023	vascular endothelial cell proliferation	4/232	53/18986	0.0754716981132075	6.17631750162654	4.19712072806371	0.00398161505714899	0.0130562775953751	0.00652138920806854	IGF2/COL4A3/TGFBR1/FLT1	4
BP	GO:0022408	negative regulation of cell-cell adhesion	8/232	207/18986	0.0386473429951691	3.16275195735466	3.47982971915988	0.00402470536413044	0.0131874637065301	0.00658691444550971	VEGFA/PDE5A/APOA1/PRKCD/PLA2G5/CDKN2A/PLG/HAVCR2	8
BP	GO:1901873	regulation of post-translational protein modification	9/232	253/18986	0.0355731225296443	2.91116941529235	3.40375363460571	0.00403605578879563	0.0132145287541272	0.00660043297772736	PLAA/SKP2/EGR1/HSPA1A/XIAP/HSPA5/CDKN2A/PPIA/TGFBR1	9
BP	GO:0048864	stem cell development	5/232	86/18986	0.0581395348837209	4.75791900561347	3.88479473443252	0.00407291674232136	0.013325012999362	0.00665561798427096	EDNRA/NRP2/LAMA5/NRP1/BCL2	5
BP	GO:0001701	in utero embryonic development	12/232	403/18986	0.0297766749379653	2.43681013091469	3.24262202688254	0.0041294085474117	0.0134995037834346	0.00674277317133297	VEGFA/PDGFRA/MYH9/ITGB1/EDNRA/TP53/IGF2/COL3A1/TGFBR1/PLG/AR/BCL2L1	12
BP	GO:0032956	regulation of actin cytoskeleton organization	11/232	352/18986	0.03125	2.55738146551724	3.28031557004128	0.00415640066829067	0.0135773638331634	0.00678166294556854	RHOA/APOA1/PDGFRB/PDGFRA/PRKCD/FLNA/BRAF/TGFBR1/PDGFA/NRP1/ALOX15	11
BP	GO:0002837	regulation of immune response to tumor cell	3/232	27/18986	0.111111111111111	9.09291187739464	4.68038218467664	0.0042424844264991	0.0137639327827846	0.00687485097146128	IL12B/HAVCR2/AHR	3
BP	GO:0010875	positive regulation of cholesterol efflux	3/232	27/18986	0.111111111111111	9.09291187739464	4.68038218467664	0.0042424844264991	0.0137639327827846	0.00687485097146128	APOA1/ABCA1/PON1	3
BP	GO:0030325	adrenal gland development	3/232	27/18986	0.111111111111111	9.09291187739464	4.68038218467664	0.0042424844264991	0.0137639327827846	0.00687485097146128	APOA1/PDGFRA/CYP1B1	3
BP	GO:0032753	positive regulation of interleukin-4 production	3/232	27/18986	0.111111111111111	9.09291187739464	4.68038218467664	0.0042424844264991	0.0137639327827846	0.00687485097146128	PRKCQ/HAVCR2/PRKCZ	3
BP	GO:0036296	response to increased oxygen levels	3/232	27/18986	0.111111111111111	9.09291187739464	4.68038218467664	0.0042424844264991	0.0137639327827846	0.00687485097146128	MMP2/CYP1A1/COL1A1	3
BP	GO:0042026	protein refolding	3/232	27/18986	0.111111111111111	9.09291187739464	4.68038218467664	0.0042424844264991	0.0137639327827846	0.00687485097146128	HSPA1A/HSPA5/HSPA8	3
BP	GO:0042104	positive regulation of activated T cell proliferation	3/232	27/18986	0.111111111111111	9.09291187739464	4.68038218467664	0.0042424844264991	0.0137639327827846	0.00687485097146128	IGF2/IL12B/PPP3CA	3
BP	GO:0045649	regulation of macrophage differentiation	3/232	27/18986	0.111111111111111	9.09291187739464	4.68038218467664	0.0042424844264991	0.0137639327827846	0.00687485097146128	PRKCA/INHBA/PF4	3
BP	GO:1904754	positive regulation of vascular associated smooth muscle cell migration	3/232	27/18986	0.111111111111111	9.09291187739464	4.68038218467664	0.0042424844264991	0.0137639327827846	0.00687485097146128	NR4A3/ADAMTS1/MDM2	3
BP	GO:0010874	regulation of cholesterol efflux	4/232	54/18986	0.0740740740740741	6.06194125159642	4.1430299214197	0.00425959954851012	0.0137880754499843	0.00688690982423765	APOA1/PLA2G10/ABCA1/PON1	4
BP	GO:0048146	positive regulation of fibroblast proliferation	4/232	54/18986	0.0740740740740741	6.06194125159642	4.1430299214197	0.00425959954851012	0.0137880754499843	0.00688690982423765	CCNA2/PDGFRA/ESR1/PDGFA	4
BP	GO:0050873	brown fat cell differentiation	4/232	54/18986	0.0740740740740741	6.06194125159642	4.1430299214197	0.00425959954851012	0.0137880754499843	0.00688690982423765	FABP4/LAMB3/INS/PTGS2	4
BP	GO:0045913	positive regulation of carbohydrate metabolic process	5/232	87/18986	0.0574712643678161	4.70323028141102	3.85055445994527	0.00427913925250552	0.0138408467804188	0.00691326820872179	SNCA/DDB1/IGF2/HTR2A/INS	5
BP	GO:0051147	regulation of muscle cell differentiation	7/232	166/18986	0.0421686746987952	3.45092438720399	3.5275768591933	0.004372376283369	0.014121058147799	0.00705322903399244	MMP14/MDM2/IGF2/LAMA1/LAMB1/LAMB2/BCL2	7
BP	GO:0070507	regulation of microtubule cytoskeleton organization	7/232	166/18986	0.0421686746987952	3.45092438720399	3.5275768591933	0.004372376283369	0.014121058147799	0.00705322903399244	SNCA/RHOA/HSPA1A/CDKN1B/TPX2/MAPT/DYRK1A	7
BP	GO:1901989	positive regulation of cell cycle phase transition	6/232	125/18986	0.048	3.92813793103448	3.65314168826884	0.00437845760252485	0.0141300261950161	0.00705770842146807	CDC7/CDK1/ADAMTS1/CYP1A1/MDM2/BRD4	6
BP	GO:0032370	positive regulation of lipid transport	5/232	88/18986	0.0568181818181818	4.64978448275862	3.81683135726276	0.00449270384079176	0.0144877840295819	0.00723640239181272	APOA1/PRKCD/PLA2G10/ABCA1/PON1	5
BP	GO:0015980	energy derivation by oxidation of organic compounds	11/232	356/18986	0.0308988764044944	2.52864684230918	3.2383819667583	0.00452033537828916	0.0145659036002746	0.00727542179236798	SNCA/NR4A3/RHOA/CDK1/CYP1A2/TP53/IGF2/COL6A1/INS/TNF/PLEC	11
BP	GO:0071560	cellular response to transforming growth factor beta stimulus	10/232	306/18986	0.0326797385620915	2.67438584629254	3.28420425073255	0.00453454585914449	0.0146006913356189	0.00729279767612886	PDE3A/HSPA1A/HSPA5/HTRA1/TP53/COL1A2/COL1A1/COL3A1/COL4A2/TGFBR1	10
BP	GO:0010959	regulation of metal ion transport	12/232	408/18986	0.0294117647058824	2.40694726166329	3.19529351633692	0.00455036391185538	0.0146077127534387	0.00729630475523783	SNCA/CRBN/PDE4D/PDE4B/PDGFRB/ITGB1/FLNA/F2/HTR2A/PPP3CA/BCL2/PTGS2	12
BP	GO:0021872	forebrain generation of neurons	4/232	55/18986	0.0727272727272727	5.95172413793103	4.09028289815295	0.00455039134414882	0.0146077127534387	0.00729630475523783	RHOA/INHBA/NRP2/NRP1	4
BP	GO:0042743	hydrogen peroxide metabolic process	4/232	55/18986	0.0727272727272727	5.95172413793103	4.09028289815295	0.00455039134414882	0.0146077127534387	0.00729630475523783	SNCA/MAOB/CYP1A1/CYP1A2	4
BP	GO:0071320	cellular response to cAMP	4/232	55/18986	0.0727272727272727	5.95172413793103	4.09028289815295	0.00455039134414882	0.0146077127534387	0.00729630475523783	PDE4D/CYP1B1/AHR/SRD5A1	4
BP	GO:0033044	regulation of chromosome organization	9/232	258/18986	0.0348837209302326	2.85475140336808	3.33620092424691	0.00458239126448913	0.0146994036361257	0.00734210279594776	CDK2/PRKCQ/ATM/ATR/CDK1/SMARCA4/TP53/LMNA/MAPT	9
BP	GO:0050851	antigen receptor-mediated signaling pathway	8/232	212/18986	0.0377358490566038	3.08815875081327	3.40059861471774	0.00464198850776611	0.0148794174356881	0.00743201663556966	PDE4D/PDE4B/PRKCH/IKBKB/BRAF/HLA-A/LIPA/BCL2	8
BP	GO:0002834	regulation of response to tumor cell	3/232	28/18986	0.107142857142857	8.76816502463054	4.57513102966019	0.00470919305737328	0.0150048506060567	0.00749466837666514	IL12B/HAVCR2/AHR	3
BP	GO:0003416	endochondral bone growth	3/232	28/18986	0.107142857142857	8.76816502463054	4.57513102966019	0.00470919305737328	0.0150048506060567	0.00749466837666514	MMP13/COL27A1/NPR2	3
BP	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	3/232	28/18986	0.107142857142857	8.76816502463054	4.57513102966019	0.00470919305737328	0.0150048506060567	0.00749466837666514	CDC7/CDK1/BRD4	3
BP	GO:0016048	detection of temperature stimulus	3/232	28/18986	0.107142857142857	8.76816502463054	4.57513102966019	0.00470919305737328	0.0150048506060567	0.00749466837666514	NTRK1/EPHB1/HTR2A	3
BP	GO:0044342	type B pancreatic cell proliferation	3/232	28/18986	0.107142857142857	8.76816502463054	4.57513102966019	0.00470919305737328	0.0150048506060567	0.00749466837666514	NR4A3/NR4A1/RAF1	3
BP	GO:0050995	negative regulation of lipid catabolic process	3/232	28/18986	0.107142857142857	8.76816502463054	4.57513102966019	0.00470919305737328	0.0150048506060567	0.00749466837666514	PDE3B/INS/TNF	3
BP	GO:0060512	prostate gland morphogenesis	3/232	28/18986	0.107142857142857	8.76816502463054	4.57513102966019	0.00470919305737328	0.0150048506060567	0.00749466837666514	MMP2/ESR1/AR	3
BP	GO:1902894	negative regulation of miRNA transcription	3/232	28/18986	0.107142857142857	8.76816502463054	4.57513102966019	0.00470919305737328	0.0150048506060567	0.00749466837666514	VEGFA/ESR1/TNF	3
BP	GO:0051250	negative regulation of lymphocyte activation	7/232	169/18986	0.0414201183431953	3.38966537441339	3.47062417845842	0.0048184788134263	0.0153416347030609	0.00766288632083862	PDE5A/INHBA/ATM/PLA2G5/CDKN2A/MICA/HAVCR2	7
BP	GO:0001954	positive regulation of cell-matrix adhesion	4/232	56/18986	0.0714285714285714	5.84544334975369	4.03882061452215	0.00485425531823758	0.015421096389884	0.00770257608563701	VEGFA/KDR/NRP1/PRKCZ	4
BP	GO:0046638	positive regulation of alpha-beta T cell differentiation	4/232	56/18986	0.0714285714285714	5.84544334975369	4.03882061452215	0.00485425531823758	0.015421096389884	0.00770257608563701	RHOA/BRD4/IL12B/PRKCZ	4
BP	GO:0085029	extracellular matrix assembly	4/232	56/18986	0.0714285714285714	5.84544334975369	4.03882061452215	0.00485425531823758	0.015421096389884	0.00770257608563701	COL1A2/COL3A1/COL6A1/TGFBR1	4
BP	GO:0008306	associative learning	5/232	90/18986	0.0555555555555556	4.54645593869732	3.75088043398877	0.00494241950024911	0.0156546561356038	0.00781923521715824	HMGCR/PDE8B/ITGB1/BRAF/SLC6A4	5
BP	GO:0048145	regulation of fibroblast proliferation	5/232	90/18986	0.0555555555555556	4.54645593869732	3.75088043398877	0.00494241950024911	0.0156546561356038	0.00781923521715824	CCNA2/PDGFRA/ESR1/TP53/PDGFA	5
BP	GO:0048708	astrocyte differentiation	5/232	90/18986	0.0555555555555556	4.54645593869732	3.75088043398877	0.00494241950024911	0.0156546561356038	0.00781923521715824	F2/LAMB2/GRN/TNF/MAPT	5
BP	GO:0050672	negative regulation of lymphocyte proliferation	5/232	90/18986	0.0555555555555556	4.54645593869732	3.75088043398877	0.00494241950024911	0.0156546561356038	0.00781923521715824	PDE5A/ATM/PLA2G5/CDKN2A/HAVCR2	5
BP	GO:0001678	intracellular glucose homeostasis	7/232	170/18986	0.0411764705882353	3.3697261663286	3.45192467117154	0.00497454333926808	0.0157447426489344	0.00786423190258673	PDE8B/CPB2/ICAM1/SMARCA4/COL1A1/RAF1/PPP3CA	7
BP	GO:0043270	positive regulation of monoatomic ion transport	8/232	215/18986	0.0372093023255814	3.04506816359262	3.35417448054159	0.00504578213382318	0.0159584056244289	0.00797095293485458	SNCA/PDGFRB/EDNRA/EPHB2/FLNA/F2/PPP3CA/SLC6A4	8
BP	GO:0001755	neural crest cell migration	4/232	57/18986	0.0701754385964912	5.74289171203872	3.98858763606487	0.00517145212716705	0.0163314060675282	0.00815726032962795	EDNRA/NRP2/LAMA5/NRP1	4
BP	GO:0051851	modulation by host of symbiont process	5/232	91/18986	0.0549450549450549	4.49649488442592	3.71862583797935	0.00517884925548599	0.0163314060675282	0.00815726032962795	EEF1A1/SMARCA4/BRD4/LTF/HSPA8	5
BP	GO:0050920	regulation of chemotaxis	8/232	216/18986	0.037037037037037	3.03097062579821	3.33887929344098	0.00518618848865574	0.0163314060675282	0.00815726032962795	VEGFA/KDR/PDGFRB/PDGFRA/CXCL8/NTRK3/KLRK1/NRP1	8
BP	GO:0021854	hypothalamus development	3/232	29/18986	0.103448275862069	8.46581450653983	4.47500707861995	0.00520573116698805	0.0163314060675282	0.00815726032962795	NRP2/NRP1/SRD5A1	3
BP	GO:0022011	myelination in peripheral nervous system	3/232	29/18986	0.103448275862069	8.46581450653983	4.47500707861995	0.00520573116698805	0.0163314060675282	0.00815726032962795	NTRK2/COL6A1/PLEC	3
BP	GO:0031342	negative regulation of cell killing	3/232	29/18986	0.103448275862069	8.46581450653983	4.47500707861995	0.00520573116698805	0.0163314060675282	0.00815726032962795	MICA/HLA-A/HAVCR2	3
BP	GO:0032292	peripheral nervous system axon ensheathment	3/232	29/18986	0.103448275862069	8.46581450653983	4.47500707861995	0.00520573116698805	0.0163314060675282	0.00815726032962795	NTRK2/COL6A1/PLEC	3
BP	GO:0042832	defense response to protozoan	3/232	29/18986	0.103448275862069	8.46581450653983	4.47500707861995	0.00520573116698805	0.0163314060675282	0.00815726032962795	IL12B/PF4/CLEC7A	3
BP	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	3/232	29/18986	0.103448275862069	8.46581450653983	4.47500707861995	0.00520573116698805	0.0163314060675282	0.00815726032962795	PDE6H/MMP9/PLAUR	3
BP	GO:0046337	phosphatidylethanolamine metabolic process	3/232	29/18986	0.103448275862069	8.46581450653983	4.47500707861995	0.00520573116698805	0.0163314060675282	0.00815726032962795	PLA2G2A/PLA2G10/ALOX15	3
BP	GO:0090594	inflammatory response to wounding	3/232	29/18986	0.103448275862069	8.46581450653983	4.47500707861995	0.00520573116698805	0.0163314060675282	0.00815726032962795	GRN/TNF/ALOX5	3
BP	GO:0050830	defense response to Gram-positive bacterium	6/232	130/18986	0.0461538461538462	3.77705570291777	3.53373371249182	0.00529476626052996	0.016598548775679	0.00829069358127434	PLA2G2A/LTF/KLRK1/HLA-A/TNF/HAVCR2	6
BP	GO:0071559	response to transforming growth factor beta	10/232	313/18986	0.0319488817891374	2.61457530020932	3.20350762377758	0.00530143072019734	0.0166072657579222	0.0082950475660539	PDE3A/HSPA1A/HSPA5/HTRA1/TP53/COL1A2/COL1A1/COL3A1/COL4A2/TGFBR1	10
BP	GO:0002292	T cell differentiation involved in immune response	5/232	92/18986	0.0543478260869565	4.44761994002998	3.68683481061885	0.00542317834031921	0.0169637970615984	0.00847312890502266	RORA/IL18R1/BRD4/IL12B/PRKCZ	5
BP	GO:0032945	negative regulation of mononuclear cell proliferation	5/232	92/18986	0.0543478260869565	4.44761994002998	3.68683481061885	0.00542317834031921	0.0169637970615984	0.00847312890502266	PDE5A/ATM/PLA2G5/CDKN2A/HAVCR2	5
BP	GO:0050796	regulation of insulin secretion	7/232	173/18986	0.0404624277456647	3.31129160853099	3.39665238853553	0.00546561300172209	0.0170840359615231	0.00853318619613275	PDE8B/PRKCA/F2/TNF/PPP3CA/HNF4A/ALOX5	7
BP	GO:0006998	nuclear envelope organization	4/232	58/18986	0.0689655172413793	5.64387633769322	3.93953185773958	0.005502238084493	0.0171734087951037	0.00857782641063104	PRKCA/ATR/CDK1/LMNA	4
BP	GO:0050805	negative regulation of synaptic transmission	4/232	58/18986	0.0689655172413793	5.64387633769322	3.93953185773958	0.005502238084493	0.0171734087951037	0.00857782641063104	HTR2A/MAPT/PTGS2/SLC6A4	4
BP	GO:0045637	regulation of myeloid cell differentiation	8/232	219/18986	0.0365296803652968	2.98945048023933	3.29351845471669	0.00562539366474735	0.0175449914737124	0.00876342565608843	PRKCA/INHBA/HSPA1A/LTF/IL12B/PF4/TNF/PPP3CA	8
BP	GO:0006937	regulation of muscle contraction	7/232	174/18986	0.0402298850574713	3.29226119698771	3.37849732386371	0.00563711592902384	0.0175687373997857	0.00877528634340139	PDE5A/PDE4D/PDE4B/RHOA/MYH7/NR4A1/PTGS2	7
BP	GO:0045824	negative regulation of innate immune response	5/232	93/18986	0.0537634408602151	4.39979606970708	3.65549519042677	0.00567554439594864	0.0176627567955432	0.00882224743689558	MICA/HLA-A/GRN/INS/HAVCR2	5
BP	GO:2000106	regulation of leukocyte apoptotic process	5/232	93/18986	0.0537634408602151	4.39979606970708	3.65549519042677	0.00567554439594864	0.0176627567955432	0.00882224743689558	PRKCQ/TP53/CDKN2A/BCL2L1/BCL2	5
BP	GO:0014046	dopamine secretion	3/232	30/18986	0.1	8.18362068965517	4.37958548046023	0.00573260740304878	0.0177756557327314	0.00887863854111368	SNCA/KCNA2/HTR2A	3
BP	GO:0045672	positive regulation of osteoclast differentiation	3/232	30/18986	0.1	8.18362068965517	4.37958548046023	0.00573260740304878	0.0177756557327314	0.00887863854111368	IL12B/TNF/PPP3CA	3
BP	GO:1900017	positive regulation of cytokine production involved in inflammatory response	3/232	30/18986	0.1	8.18362068965517	4.37958548046023	0.00573260740304878	0.0177756557327314	0.00887863854111368	IL17RA/CLEC7A/TNF	3
BP	GO:1900746	regulation of vascular endothelial growth factor signaling pathway	3/232	30/18986	0.1	8.18362068965517	4.37958548046023	0.00573260740304878	0.0177756557327314	0.00887863854111368	VEGFA/ITGB1/IL12B	3
BP	GO:2000629	negative regulation of miRNA metabolic process	3/232	30/18986	0.1	8.18362068965517	4.37958548046023	0.00573260740304878	0.0177756557327314	0.00887863854111368	VEGFA/ESR1/TNF	3
BP	GO:0007632	visual behavior	4/232	59/18986	0.0677966101694915	5.54821741671537	3.8916042501856	0.00584686504341457	0.0180775089845558	0.00902940912059076	HMGCR/PDE8B/ITGB1/BRAF	4
BP	GO:0046902	regulation of mitochondrial membrane permeability	4/232	59/18986	0.0677966101694915	5.54821741671537	3.8916042501856	0.00584686504341457	0.0180775089845558	0.00902940912059076	HSPA1A/TP53/BCL2L1/BCL2	4
BP	GO:0060135	maternal process involved in female pregnancy	4/232	59/18986	0.0677966101694915	5.54821741671537	3.8916042501856	0.00584686504341457	0.0180775089845558	0.00902940912059076	ESR1/HAVCR2/AR/PTGS2	4
BP	GO:0090497	mesenchymal cell migration	4/232	59/18986	0.0677966101694915	5.54821741671537	3.8916042501856	0.00584686504341457	0.0180775089845558	0.00902940912059076	EDNRA/NRP2/LAMA5/NRP1	4
BP	GO:0046889	positive regulation of lipid biosynthetic process	5/232	94/18986	0.0531914893617021	4.35298972853998	3.6245952645645	0.0059360842819401	0.0183400985473814	0.00916056815337425	PRKCD/HTR2A/INS/TNF/PTGS2	5
BP	GO:0007601	visual perception	8/232	222/18986	0.036036036036036	2.94905250077664	3.24892473178641	0.00609242515749961	0.0187176857148342	0.00934916653916562	PDE6H/PDE6A/PDE6C/COL1A1/COL2A1/COL11A1/COL18A1/LAMB2	8
BP	GO:0010639	negative regulation of organelle organization	11/232	371/18986	0.0296495956873315	2.42641044706757	3.08604520099011	0.00611664505344941	0.0187176857148342	0.00934916653916562	SNCA/PRKCD/ATM/HSPA1A/TP53/TPX2/LMNA/HGF/MAPT/BCL2L1/DYRK1A	11
BP	GO:0038061	non-canonical NF-kappaB signal transduction	6/232	134/18986	0.0447761194029851	3.66430777148739	3.44239270360137	0.00612325294914904	0.0187176857148342	0.00934916653916562	RHOA/CHUK/IL18R1/IL12B/TNF/HAVCR2	6
BP	GO:0051384	response to glucocorticoid	6/232	134/18986	0.0447761194029851	3.66430777148739	3.44239270360137	0.00612325294914904	0.0187176857148342	0.00934916653916562	MAOB/CYP1B1/TNF/BCL2/PTGS2/SRD5A1	6
BP	GO:0001894	tissue homeostasis	9/232	270/18986	0.0333333333333333	2.72787356321839	3.18045797256795	0.00612917061932224	0.0187176857148342	0.00934916653916562	VEGFA/PRKCA/ITGB1/XIAP/COL2A1/COL3A1/LIPA/BCL2/PTGS2	9
BP	GO:0060249	anatomical structure homeostasis	9/232	270/18986	0.0333333333333333	2.72787356321839	3.18045797256795	0.00612917061932224	0.0187176857148342	0.00934916653916562	VEGFA/PRKCA/ITGB1/XIAP/COL2A1/COL3A1/LIPA/BCL2/PTGS2	9
BP	GO:0010660	regulation of muscle cell apoptotic process	5/232	95/18986	0.0526315789473684	4.30716878402904	3.59412374766984	0.00620493402161289	0.0187176857148342	0.00934916653916562	ESR1/TP53/CDKN2A/IL12B/HSPA8	5
BP	GO:0048704	embryonic skeletal system morphogenesis	5/232	95/18986	0.0526315789473684	4.30716878402904	3.59412374766984	0.00620493402161289	0.0187176857148342	0.00934916653916562	PDGFRA/MMP14/COL2A1/COL11A1/TGFBR1	5
BP	GO:0051492	regulation of stress fiber assembly	5/232	95/18986	0.0526315789473684	4.30716878402904	3.59412374766984	0.00620493402161289	0.0187176857148342	0.00934916653916562	RHOA/APOA1/BRAF/TGFBR1/NRP1	5
BP	GO:0090316	positive regulation of intracellular protein transport	5/232	95/18986	0.0526315789473684	4.30716878402904	3.59412374766984	0.00620493402161289	0.0187176857148342	0.00934916653916562	PRKCD/CDK1/FLNA/MDM2/PTGS2	5
BP	GO:0002707	negative regulation of lymphocyte mediated immunity	4/232	60/18986	0.0666666666666667	5.45574712643678	3.84475862926567	0.00620558028655515	0.0187176857148342	0.00934916653916562	MICA/HLA-A/HAVCR2/AHR	4
BP	GO:0050881	musculoskeletal movement	4/232	60/18986	0.0666666666666667	5.45574712643678	3.84475862926567	0.00620558028655515	0.0187176857148342	0.00934916653916562	CHUK/MYH7/NR4A1/TNF	4
BP	GO:0055008	cardiac muscle tissue morphogenesis	4/232	60/18986	0.0666666666666667	5.45574712643678	3.84475862926567	0.00620558028655515	0.0187176857148342	0.00934916653916562	EDNRA/MYH7/COL11A1/TGFBR1	4
BP	GO:1901616	organic hydroxy compound catabolic process	4/232	60/18986	0.0666666666666667	5.45574712643678	3.84475862926567	0.00620558028655515	0.0187176857148342	0.00934916653916562	MAOA/MAOB/CYP3A4/SLC6A3	4
BP	GO:0007178	cell surface receptor protein serine/threonine kinase signaling pathway	12/232	425/18986	0.0282352941176471	2.31066937119675	3.03940985713352	0.00624522441521035	0.0187176857148342	0.00934916653916562	KDR/EGR1/INHBA/HSPA1A/XIAP/HSPA5/HTRA1/MAP1LC3A/TP53/COL1A2/COL3A1/TGFBR1	12
BP	GO:1903828	negative regulation of protein localization	8/232	223/18986	0.0358744394618834	2.93582805010051	3.23422632751088	0.00625447516778815	0.0187176857148342	0.00934916653916562	HMGCR/PDE8B/IL12B/INS/PPP3CA/POLR1A/MAPT/BCL2L1	8
BP	GO:0001788	antibody-dependent cellular cytotoxicity	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	FCGR2A/FCGR3A	2
BP	GO:0002420	natural killer cell mediated cytotoxicity directed against tumor cell target	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	IL12B/HAVCR2	2
BP	GO:0002855	regulation of natural killer cell mediated immune response to tumor cell	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	IL12B/HAVCR2	2
BP	GO:0009624	response to nematode	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	CYP1A1/PTGS2	2
BP	GO:0009750	response to fructose	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	TNF/PTGS2	2
BP	GO:0014820	tonic smooth muscle contraction	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	EDNRA/HTR2A	2
BP	GO:0032070	regulation of deoxyribonuclease activity	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	PRKCD/GZMA	2
BP	GO:0032225	regulation of synaptic transmission, dopaminergic	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	PTGS2/SLC6A4	2
BP	GO:0032627	interleukin-23 production	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	IL17RA/CLEC7A	2
BP	GO:0032667	regulation of interleukin-23 production	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	IL17RA/CLEC7A	2
BP	GO:0032815	negative regulation of natural killer cell activation	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	MICA/HAVCR2	2
BP	GO:0032819	positive regulation of natural killer cell proliferation	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	IL12B/FCGR3A	2
BP	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	SKP2/AR	2
BP	GO:0055015	ventricular cardiac muscle cell development	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	CDK1/LMNA	2
BP	GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	CDKN1B/AR	2
BP	GO:0071372	cellular response to follicle-stimulating hormone stimulus	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	INHBA/EDNRA	2
BP	GO:0071803	positive regulation of podosome assembly	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	RHOA/TNF	2
BP	GO:0071838	cell proliferation in bone marrow	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	SHC1/LIPA	2
BP	GO:0072203	cell proliferation involved in metanephros development	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	PDGFRB/EGR1	2
BP	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	VEGFA/ITGB1	2
BP	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	NTRK2/MAPT	2
BP	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin	2/232	10/18986	0.2	16.3672413793103	5.40624738157437	0.00627175973394475	0.0187176857148342	0.00934916653916562	VEGFA/PLG	2
BP	GO:0001516	prostaglandin biosynthetic process	3/232	31/18986	0.0967741935483871	7.91963292547275	4.28848945358813	0.00629029802904975	0.0187176857148342	0.00934916653916562	PLA2G10/PTGS1/PTGS2	3
BP	GO:0001945	lymph vessel development	3/232	31/18986	0.0967741935483871	7.91963292547275	4.28848945358813	0.00629029802904975	0.0187176857148342	0.00934916653916562	VEGFA/KDR/NPR2	3
BP	GO:0014850	response to muscle activity	3/232	31/18986	0.0967741935483871	7.91963292547275	4.28848945358813	0.00629029802904975	0.0187176857148342	0.00934916653916562	ITGB1/COL6A1/SRD5A1	3
BP	GO:0031281	positive regulation of cyclase activity	3/232	31/18986	0.0967741935483871	7.91963292547275	4.28848945358813	0.00629029802904975	0.0187176857148342	0.00934916653916562	EDNRA/RAF1/ADORA3	3
BP	GO:0036336	dendritic cell migration	3/232	31/18986	0.0967741935483871	7.91963292547275	4.28848945358813	0.00629029802904975	0.0187176857148342	0.00934916653916562	CXCR1/CXCR2/ALOX5	3
BP	GO:0040018	positive regulation of multicellular organism growth	3/232	31/18986	0.0967741935483871	7.91963292547275	4.28848945358813	0.00629029802904975	0.0187176857148342	0.00934916653916562	IGF2/BCL2/SLC6A3	3
BP	GO:0046457	prostanoid biosynthetic process	3/232	31/18986	0.0967741935483871	7.91963292547275	4.28848945358813	0.00629029802904975	0.0187176857148342	0.00934916653916562	PLA2G10/PTGS1/PTGS2	3
BP	GO:0046685	response to arsenic-containing substance	3/232	31/18986	0.0967741935483871	7.91963292547275	4.28848945358813	0.00629029802904975	0.0187176857148342	0.00934916653916562	ATR/CYP1A1/CYP1B1	3
BP	GO:0051349	positive regulation of lyase activity	3/232	31/18986	0.0967741935483871	7.91963292547275	4.28848945358813	0.00629029802904975	0.0187176857148342	0.00934916653916562	EDNRA/RAF1/ADORA3	3
BP	GO:0070723	response to cholesterol	3/232	31/18986	0.0967741935483871	7.91963292547275	4.28848945358813	0.00629029802904975	0.0187176857148342	0.00934916653916562	INHBA/ABCA1/TGFBR1	3
BP	GO:0098868	bone growth	3/232	31/18986	0.0967741935483871	7.91963292547275	4.28848945358813	0.00629029802904975	0.0187176857148342	0.00934916653916562	MMP13/COL27A1/NPR2	3
BP	GO:0150117	positive regulation of cell-substrate junction organization	3/232	31/18986	0.0967741935483871	7.91963292547275	4.28848945358813	0.00629029802904975	0.0187176857148342	0.00934916653916562	VEGFA/KDR/NRP1	3
BP	GO:1901186	positive regulation of ERBB signaling pathway	3/232	31/18986	0.0967741935483871	7.91963292547275	4.28848945358813	0.00629029802904975	0.0187176857148342	0.00934916653916562	PDE6H/MMP9/PLAUR	3
BP	GO:1901798	positive regulation of signal transduction by p53 class mediator	3/232	31/18986	0.0967741935483871	7.91963292547275	4.28848945358813	0.00629029802904975	0.0187176857148342	0.00934916653916562	ATM/ATR/CDKN2A	3
BP	GO:1902751	positive regulation of cell cycle G2/M phase transition	3/232	31/18986	0.0967741935483871	7.91963292547275	4.28848945358813	0.00629029802904975	0.0187176857148342	0.00934916653916562	CDC7/CDK1/BRD4	3
BP	GO:0010506	regulation of autophagy	11/232	373/18986	0.0294906166219839	2.41340020338356	3.0662934411893	0.006359331783292	0.0189099462485095	0.00944519741475695	KDR/SNCA/PSAP/CTSA/EEF1A1/ATM/TP53/HGF/MAPT/BCL2L1/BCL2	11
BP	GO:0006096	glycolytic process	5/232	96/18986	0.0520833333333333	4.26230244252874	3.56406976190219	0.00648222874851585	0.0192619945299887	0.00962103956017604	ALDOA/COL6A1/HTR2A/INS/LIPA	5
BP	GO:1904950	negative regulation of establishment of protein localization	6/232	136/18986	0.0441176470588235	3.61042089249493	3.39802563522783	0.00657116097288048	0.0194807524819862	0.00973030544678994	HMGCR/PDE8B/IL12B/INS/PPP3CA/MAPT	6
BP	GO:0001913	T cell mediated cytotoxicity	4/232	61/18986	0.0655737704918033	5.36630864895421	3.79895144640546	0.0065786264228223	0.0194807524819862	0.00973030544678994	IL12B/HSPA8/MICA/HLA-A	4
BP	GO:0042306	regulation of protein import into nucleus	4/232	61/18986	0.0655737704918033	5.36630864895421	3.79895144640546	0.0065786264228223	0.0194807524819862	0.00973030544678994	PRKCD/CDK1/FLNA/PTGS2	4
BP	GO:0043113	receptor clustering	4/232	61/18986	0.0655737704918033	5.36630864895421	3.79895144640546	0.0065786264228223	0.0194807524819862	0.00973030544678994	ITGAL/ITGB2/ITGB7/FLNA	4
BP	GO:0070231	T cell apoptotic process	4/232	61/18986	0.0655737704918033	5.36630864895421	3.79895144640546	0.0065786264228223	0.0194807524819862	0.00973030544678994	PRKCQ/TP53/LIPA/BCL2	4
BP	GO:0050953	sensory perception of light stimulus	8/232	226/18986	0.0353982300884956	2.89685688129387	3.19061721651213	0.00676031453288786	0.0200049169153138	0.00999211669075175	PDE6H/PDE6A/PDE6C/COL1A1/COL2A1/COL11A1/COL18A1/LAMB2	8
BP	GO:0010950	positive regulation of endopeptidase activity	6/232	137/18986	0.0437956204379562	3.58406745532343	3.37615448052377	0.00680382456195473	0.020091957062789	0.0100355917681057	SNCA/CDKN2A/COL4A3/CLEC7A/TNF/MAPT	6
BP	GO:0045621	positive regulation of lymphocyte differentiation	6/232	137/18986	0.0437956204379562	3.58406745532343	3.37615448052377	0.00680382456195473	0.020091957062789	0.0100355917681057	RHOA/SMARCA4/MMP14/BRD4/IL12B/PRKCZ	6
BP	GO:0051592	response to calcium ion	6/232	137/18986	0.0437956204379562	3.58406745532343	3.37615448052377	0.00680382456195473	0.020091957062789	0.0100355917681057	FGA/FGB/FGG/BRAF/PPP3CA/ALOX15	6
BP	GO:0001562	response to protozoan	3/232	32/18986	0.09375	7.67214439655172	4.20138349471888	0.00687924781854633	0.0201672379142257	0.0100731932765408	IL12B/PF4/CLEC7A	3
BP	GO:0003299	muscle hypertrophy in response to stress	3/232	32/18986	0.09375	7.67214439655172	4.20138349471888	0.00687924781854633	0.0201672379142257	0.0100731932765408	LMNA/MYH7/PPP3CA	3
BP	GO:0010575	positive regulation of vascular endothelial growth factor production	3/232	32/18986	0.09375	7.67214439655172	4.20138349471888	0.00687924781854633	0.0201672379142257	0.0100731932765408	RORA/CYP1B1/PTGS2	3
BP	GO:0014887	cardiac muscle adaptation	3/232	32/18986	0.09375	7.67214439655172	4.20138349471888	0.00687924781854633	0.0201672379142257	0.0100731932765408	LMNA/MYH7/PPP3CA	3
BP	GO:0014898	cardiac muscle hypertrophy in response to stress	3/232	32/18986	0.09375	7.67214439655172	4.20138349471888	0.00687924781854633	0.0201672379142257	0.0100731932765408	LMNA/MYH7/PPP3CA	3
BP	GO:0048679	regulation of axon regeneration	3/232	32/18986	0.09375	7.67214439655172	4.20138349471888	0.00687924781854633	0.0201672379142257	0.0100731932765408	FLNA/BRAF/GRN	3
BP	GO:0051085	chaperone cofactor-dependent protein refolding	3/232	32/18986	0.09375	7.67214439655172	4.20138349471888	0.00687924781854633	0.0201672379142257	0.0100731932765408	HSPA1A/HSPA5/HSPA8	3
BP	GO:0060325	face morphogenesis	3/232	32/18986	0.09375	7.67214439655172	4.20138349471888	0.00687924781854633	0.0201672379142257	0.0100731932765408	MMP2/PDGFRA/COL1A1	3
BP	GO:0060603	mammary gland duct morphogenesis	3/232	32/18986	0.09375	7.67214439655172	4.20138349471888	0.00687924781854633	0.0201672379142257	0.0100731932765408	DDR1/ESR1/AR	3
BP	GO:1902547	regulation of cellular response to vascular endothelial growth factor stimulus	3/232	32/18986	0.09375	7.67214439655172	4.20138349471888	0.00687924781854633	0.0201672379142257	0.0100731932765408	VEGFA/ITGB1/IL12B	3
BP	GO:0006898	receptor-mediated endocytosis	9/232	275/18986	0.0327272727272727	2.67827586206897	3.11805328905778	0.00688119740805784	0.0201672379142257	0.0100731932765408	VEGFA/SNCA/ITGB1/ITGB2/CXCL8/MDM2/AP2A1/CXCR1/CXCR2	9
BP	GO:0007004	telomere maintenance via telomerase	4/232	62/18986	0.0645161290322581	5.2797552836485	3.75414159754567	0.00696624129112912	0.0203885337172266	0.0101837267766857	ATM/ATR/RPA1/TP53	4
BP	GO:0048010	vascular endothelial growth factor receptor signaling pathway	4/232	62/18986	0.0645161290322581	5.2797552836485	3.75414159754567	0.00696624129112912	0.0203885337172266	0.0101837267766857	VEGFA/KDR/NRP1/FLT1	4
BP	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	6/232	138/18986	0.0434782608695652	3.55809595202399	3.35448670119869	0.00704240585500949	0.0205832723417776	0.0102809954166379	VEGFA/EDNRA/ESR1/F2/HTR2A/CXCR2	6
BP	GO:0050768	negative regulation of neurogenesis	6/232	138/18986	0.0434782608695652	3.55809595202399	3.35448670119869	0.00704240585500949	0.0205832723417776	0.0102809954166379	TP53/EPHB2/F2/NRP1/TNF/PPP3CA	6
BP	GO:0002275	myeloid cell activation involved in immune response	5/232	98/18986	0.0510204081632653	4.1753166783955	3.50517279809605	0.00706268893591131	0.0206143739863186	0.0102965301605634	NR4A3/ITGB2/GRN/TNF/HAVCR2	5
BP	GO:0046032	ADP catabolic process	5/232	98/18986	0.0510204081632653	4.1753166783955	3.50517279809605	0.00706268893591131	0.0206143739863186	0.0102965301605634	ALDOA/COL6A1/HTR2A/INS/LIPA	5
BP	GO:0046034	ATP metabolic process	8/232	228/18986	0.0350877192982456	2.87144585601936	3.16194099915404	0.00711435794042167	0.0207510194769734	0.0103647822654668	HSPA1A/ALDOA/MYH7/COL6A1/HTR2A/HSPA8/INS/LIPA	8
BP	GO:0002221	pattern recognition receptor signaling pathway	9/232	278/18986	0.0323741007194245	2.64937360456462	3.0812724070119	0.00736523267687586	0.0214197016012147	0.0106987776448389	ESR1/IKBKB/CHUK/HSPA1A/XIAP/LTF/HSPA8/TNF/HAVCR2	9
BP	GO:0051262	protein tetramerization	5/232	99/18986	0.0505050505050505	4.13314176245211	3.47630993776008	0.00736611974836997	0.0214197016012147	0.0106987776448389	SNCA/TP53/ALDOA/COL6A1/TRPA1	5
BP	GO:0070664	negative regulation of leukocyte proliferation	5/232	99/18986	0.0505050505050505	4.13314176245211	3.47630993776008	0.00736611974836997	0.0214197016012147	0.0106987776448389	PDE5A/ATM/PLA2G5/CDKN2A/HAVCR2	5
BP	GO:0002262	myeloid cell homeostasis	7/232	183/18986	0.0382513661202186	3.13034671188996	3.22080624328828	0.00736746597912483	0.0214197016012147	0.0106987776448389	VEGFA/PDE4B/INHBA/THRA/HSPA1A/PLA2G10/LIPA	7
BP	GO:0003229	ventricular cardiac muscle tissue development	4/232	63/18986	0.0634920634920635	5.19594964422551	3.71029024878311	0.00736865787076399	0.0214197016012147	0.0106987776448389	EDNRA/MYH7/COL11A1/TGFBR1	4
BP	GO:0010948	negative regulation of cell cycle process	10/232	329/18986	0.0303951367781155	2.48742270202285	3.02700951597727	0.00743613167142998	0.0216011542303224	0.0107894101554144	CDK2/INHBA/ATM/ATR/CDK1/CDKN1B/TP53/MDM2/BRD4/BCL2	10
BP	GO:0010464	regulation of mesenchymal cell proliferation	3/232	33/18986	0.0909090909090909	7.43965517241379	4.11796772599027	0.00749987093040724	0.0216333679270187	0.0108055003505295	KDR/LMNA/PDGFA	3
BP	GO:0031116	positive regulation of microtubule polymerization	3/232	33/18986	0.0909090909090909	7.43965517241379	4.11796772599027	0.00749987093040724	0.0216333679270187	0.0108055003505295	HSPA1A/CDKN1B/MAPT	3
BP	GO:0031952	regulation of protein autophosphorylation	3/232	33/18986	0.0909090909090909	7.43965517241379	4.11796772599027	0.00749987093040724	0.0216333679270187	0.0108055003505295	VEGFA/PDGFA/INS	3
BP	GO:0033032	regulation of myeloid cell apoptotic process	3/232	33/18986	0.0909090909090909	7.43965517241379	4.11796772599027	0.00749987093040724	0.0216333679270187	0.0108055003505295	THRA/CDKN2A/BCL2	3
BP	GO:0042573	retinoic acid metabolic process	3/232	33/18986	0.0909090909090909	7.43965517241379	4.11796772599027	0.00749987093040724	0.0216333679270187	0.0108055003505295	CYP3A4/CYP1A1/CYP2S1	3
BP	GO:0048566	embryonic digestive tract development	3/232	33/18986	0.0909090909090909	7.43965517241379	4.11796772599027	0.00749987093040724	0.0216333679270187	0.0108055003505295	PDGFRA/CXCL8/TNF	3
BP	GO:0050869	negative regulation of B cell activation	3/232	33/18986	0.0909090909090909	7.43965517241379	4.11796772599027	0.00749987093040724	0.0216333679270187	0.0108055003505295	INHBA/ATM/CDKN2A	3
BP	GO:0060219	camera-type eye photoreceptor cell differentiation	3/232	33/18986	0.0909090909090909	7.43965517241379	4.11796772599027	0.00749987093040724	0.0216333679270187	0.0108055003505295	NTRK2/PDE6C/THRB	3
BP	GO:0099170	postsynaptic modulation of chemical synaptic transmission	3/232	33/18986	0.0909090909090909	7.43965517241379	4.11796772599027	0.00749987093040724	0.0216333679270187	0.0108055003505295	MDM2/BRAF/PPP3CA	3
BP	GO:0008360	regulation of cell shape	6/232	140/18986	0.0428571428571429	3.50726600985222	3.31174717807341	0.00753765420389417	0.0216333679270187	0.0108055003505295	VEGFA/KDR/MYH9/ITGB2/ALDOA/F2	6
BP	GO:0001660	fever generation	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	TNF/PTGS2	2
BP	GO:0001794	type IIa hypersensitivity	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	FCGR2A/FCGR3A	2
BP	GO:0002423	natural killer cell mediated immune response to tumor cell	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	IL12B/HAVCR2	2
BP	GO:0002445	type II hypersensitivity	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	FCGR2A/FCGR3A	2
BP	GO:0006983	ER overload response	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	HSPA5/TP53	2
BP	GO:0019372	lipoxygenase pathway	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	ALOX5/ALOX15	2
BP	GO:0021561	facial nerve development	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	NRP2/NRP1	2
BP	GO:0021610	facial nerve morphogenesis	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	NRP2/NRP1	2
BP	GO:0031915	positive regulation of synaptic plasticity	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	EPHB2/PTGS2	2
BP	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	SKP2/AR	2
BP	GO:0033327	Leydig cell differentiation	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	PDGFRA/AR	2
BP	GO:0042118	endothelial cell activation	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	PPIA/TGFBR1	2
BP	GO:0042428	serotonin metabolic process	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	HTR1A/SRD5A1	2
BP	GO:0044829	positive regulation by host of viral genome replication	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	EEF1A1/HSPA8	2
BP	GO:0046477	glycosylceramide catabolic process	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	PRKCD/GLA	2
BP	GO:0046549	retinal cone cell development	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	PDE6C/THRB	2
BP	GO:0051838	cytolysis by host of symbiont cells	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	LTF/F2	2
BP	GO:0060742	epithelial cell differentiation involved in prostate gland development	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	PSAP/AR	2
BP	GO:0060767	epithelial cell proliferation involved in prostate gland development	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	CDKN1B/AR	2
BP	GO:1900222	negative regulation of amyloid-beta clearance	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	HMGCR/TNF	2
BP	GO:2000672	negative regulation of motor neuron apoptotic process	2/232	11/18986	0.181818181818182	14.8793103448276	5.12124643272691	0.00760405799679821	0.0216333679270187	0.0108055003505295	RHOA/BCL2	2
BP	GO:0002220	innate immune response activating cell surface receptor signaling pathway	5/232	100/18986	0.05	4.09181034482759	3.44782481130691	0.00767852615271234	0.0218161978930219	0.0108968208175229	IKBKB/CHUK/LTF/KLRK1/CLEC7A	5
BP	GO:0019364	pyridine nucleotide catabolic process	5/232	100/18986	0.05	4.09181034482759	3.44782481130691	0.00767852615271234	0.0218161978930219	0.0108968208175229	ALDOA/COL6A1/HTR2A/INS/LIPA	5
BP	GO:0009311	oligosaccharide metabolic process	4/232	64/18986	0.0625	5.11476293103448	3.66736067700309	0.00778610419820082	0.0220924894170582	0.0110348237475287	GLA/B4GALT1/MAN2B1/MANBA	4
BP	GO:0033619	membrane protein proteolysis	4/232	64/18986	0.0625	5.11476293103448	3.66736067700309	0.00778610419820082	0.0220924894170582	0.0110348237475287	MYH9/PRKCQ/ERAP1/TNF	4
BP	GO:0019730	antimicrobial humoral response	7/232	185/18986	0.0378378378378378	3.09650512581547	3.18708506662386	0.00780015127824912	0.0221176703354066	0.0110474011891438	CXCL8/LTF/F2/FGA/FGB/PF4/HLA-A	7
BP	GO:0006942	regulation of striated muscle contraction	5/232	101/18986	0.0495049504950495	4.05129737111642	3.41970831620858	0.00800003806953259	0.0226394194475985	0.0113080060211652	PDE5A/PDE4D/PDE4B/MYH7/NR4A1	5
BP	GO:0009137	purine nucleoside diphosphate catabolic process	5/232	101/18986	0.0495049504950495	4.05129737111642	3.41970831620858	0.00800003806953259	0.0226394194475985	0.0113080060211652	ALDOA/COL6A1/HTR2A/INS/LIPA	5
BP	GO:0009181	purine ribonucleoside diphosphate catabolic process	5/232	101/18986	0.0495049504950495	4.05129737111642	3.41970831620858	0.00800003806953259	0.0226394194475985	0.0113080060211652	ALDOA/COL6A1/HTR2A/INS/LIPA	5
BP	GO:0031109	microtubule polymerization or depolymerization	6/232	142/18986	0.0422535211267606	3.4578678970374	3.26977974274179	0.00805756877203508	0.0227871455484272	0.0113817927029095	SNCA/HSPA1A/CDKN1B/TPX2/MAPT/DYRK1A	6
BP	GO:0006691	leukotriene metabolic process	3/232	34/18986	0.0882352941176471	7.22084178498986	4.03797316142497	0.00815255176539967	0.0229344153610849	0.0114553514764515	PLA2G5/LTA4H/ALOX5	3
BP	GO:0050901	leukocyte tethering or rolling	3/232	34/18986	0.0882352941176471	7.22084178498986	4.03797316142497	0.00815255176539967	0.0229344153610849	0.0114553514764515	ITGB1/ITGB7/TNF	3
BP	GO:0051873	killing by host of symbiont cells	3/232	34/18986	0.0882352941176471	7.22084178498986	4.03797316142497	0.00815255176539967	0.0229344153610849	0.0114553514764515	LTF/F2/PF4	3
BP	GO:0070498	interleukin-1-mediated signaling pathway	3/232	34/18986	0.0882352941176471	7.22084178498986	4.03797316142497	0.00815255176539967	0.0229344153610849	0.0114553514764515	IL1R1/EGR1/IKBKB	3
BP	GO:0070570	regulation of neuron projection regeneration	3/232	34/18986	0.0882352941176471	7.22084178498986	4.03797316142497	0.00815255176539967	0.0229344153610849	0.0114553514764515	FLNA/BRAF/GRN	3
BP	GO:1901889	negative regulation of cell junction assembly	3/232	34/18986	0.0882352941176471	7.22084178498986	4.03797316142497	0.00815255176539967	0.0229344153610849	0.0114553514764515	IKBKB/MMP14/TNF	3
BP	GO:1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	3/232	34/18986	0.0882352941176471	7.22084178498986	4.03797316142497	0.00815255176539967	0.0229344153610849	0.0114553514764515	TP53/MDM2/BCL2	3
BP	GO:1903715	regulation of aerobic respiration	3/232	34/18986	0.0882352941176471	7.22084178498986	4.03797316142497	0.00815255176539967	0.0229344153610849	0.0114553514764515	SNCA/RHOA/TNF	3
BP	GO:0010573	vascular endothelial growth factor production	4/232	65/18986	0.0615384615384615	5.03607427055703	3.62531812400162	0.00821880329014748	0.0230904092435418	0.0115332677748871	RORA/CYP1B1/TNF/PTGS2	4
BP	GO:1903078	positive regulation of protein localization to plasma membrane	4/232	65/18986	0.0615384615384615	5.03607427055703	3.62531812400162	0.00821880329014748	0.0230904092435418	0.0115332677748871	ITGB1/PRKCH/EPHB2/TNF	4
BP	GO:0006260	DNA replication	9/232	283/18986	0.0318021201413428	2.60256488363592	3.02103349311636	0.00822935865468784	0.0231048835242582	0.011540497432603	CDC7/CDK2/CCNA2/ATR/CDK1/CDKN1B/RPA1/TP53/POLD3	9
BP	GO:0048813	dendrite morphogenesis	6/232	143/18986	0.041958041958042	3.43368700265252	3.24907738085597	0.00832698176290721	0.023313110847825	0.0116445034489284	ITGB1/EPHB2/EPHB3/EPHB1/NRP1/PPP3CA	6
BP	GO:0035282	segmentation	5/232	102/18986	0.0490196078431373	4.01157876943881	3.39195165901699	0.00833078423187013	0.023313110847825	0.0116445034489284	NRP2/ATM/TP53/LAMA5/NRP1	5
BP	GO:0042157	lipoprotein metabolic process	5/232	102/18986	0.0490196078431373	4.01157876943881	3.39195165901699	0.00833078423187013	0.023313110847825	0.0116445034489284	APOA1/ATM/ABCA1/OLR1/LIPA	5
BP	GO:1990868	response to chemokine	5/232	102/18986	0.0490196078431373	4.01157876943881	3.39195165901699	0.00833078423187013	0.023313110847825	0.0116445034489284	RHOA/CXCL8/CXCR1/PF4/CXCR2	5
BP	GO:1990869	cellular response to chemokine	5/232	102/18986	0.0490196078431373	4.01157876943881	3.39195165901699	0.00833078423187013	0.023313110847825	0.0116445034489284	RHOA/CXCL8/CXCR1/PF4/CXCR2	5
BP	GO:0002931	response to ischemia	4/232	66/18986	0.0606060606060606	4.95977011494253	3.58412966276722	0.00866697307263384	0.0241264238861693	0.0120507395167735	EGR1/TP53/NPR3/BCL2	4
BP	GO:0032613	interleukin-10 production	4/232	66/18986	0.0606060606060606	4.95977011494253	3.58412966276722	0.00866697307263384	0.0241264238861693	0.0120507395167735	IL12B/CLEC7A/PRKCZ/HGF	4
BP	GO:0032653	regulation of interleukin-10 production	4/232	66/18986	0.0606060606060606	4.95977011494253	3.58412966276722	0.00866697307263384	0.0241264238861693	0.0120507395167735	IL12B/CLEC7A/PRKCZ/HGF	4
BP	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	4/232	66/18986	0.0606060606060606	4.95977011494253	3.58412966276722	0.00866697307263384	0.0241264238861693	0.0120507395167735	HSPA1A/TP53/BCL2L1/BCL2	4
BP	GO:0070534	protein K63-linked ubiquitination	4/232	66/18986	0.0606060606060606	4.95977011494253	3.58412966276722	0.00866697307263384	0.0241264238861693	0.0120507395167735	PLAA/SKP2/XIAP/CDKN2A	4
BP	GO:0034308	primary alcohol metabolic process	5/232	103/18986	0.0485436893203883	3.97263140274523	3.3645463419256	0.00867089213953337	0.0241264238861693	0.0120507395167735	CYP3A4/CYP1A1/CYP1A2/CYP2D6/CYP1B1	5
BP	GO:0034766	negative regulation of monoatomic ion transmembrane transport	5/232	103/18986	0.0485436893203883	3.97263140274523	3.3645463419256	0.00867089213953337	0.0241264238861693	0.0120507395167735	CRBN/MMP9/EPHB2/PPP3CA/BCL2	5
BP	GO:0072526	pyridine-containing compound catabolic process	5/232	103/18986	0.0485436893203883	3.97263140274523	3.3645463419256	0.00867089213953337	0.0241264238861693	0.0120507395167735	ALDOA/COL6A1/HTR2A/INS/LIPA	5
BP	GO:0002685	regulation of leukocyte migration	8/232	236/18986	0.0338983050847458	2.77410870835769	3.05026752128062	0.00867219679912118	0.0241264238861693	0.0120507395167735	VEGFA/RHOA/ICAM1/IL1R1/CXCL8/MMP14/KLRK1/TNF	8
BP	GO:0097553	calcium ion transmembrane import into cytosol	7/232	189/18986	0.037037037037037	3.03097062579821	3.12099167997848	0.00872146397277532	0.0242477112793155	0.012111320512464	SNCA/PDE4D/FLNA/F2/HTR2A/PPP3CA/BCL2	7
BP	GO:0032633	interleukin-4 production	3/232	35/18986	0.0857142857142857	7.01453201970443	3.96115772099955	0.00883764580445417	0.0245020729893789	0.0122383698723475	PRKCQ/HAVCR2/PRKCZ	3
BP	GO:0032673	regulation of interleukin-4 production	3/232	35/18986	0.0857142857142857	7.01453201970443	3.96115772099955	0.00883764580445417	0.0245020729893789	0.0122383698723475	PRKCQ/HAVCR2/PRKCZ	3
BP	GO:0038094	Fc-gamma receptor signaling pathway	3/232	35/18986	0.0857142857142857	7.01453201970443	3.96115772099955	0.00883764580445417	0.0245020729893789	0.0122383698723475	PRKCD/FCGR2A/FCGR3A	3
BP	GO:0090075	relaxation of muscle	3/232	35/18986	0.0857142857142857	7.01453201970443	3.96115772099955	0.00883764580445417	0.0245020729893789	0.0122383698723475	PDE5A/PDE4D/PDE4B	3
BP	GO:0006816	calcium ion transport	12/232	445/18986	0.0269662921348315	2.20681906237892	2.86521969240554	0.00884160398096625	0.0245020729893789	0.0122383698723475	SNCA/PDE4D/PDE4B/PDGFRB/EDNRA/FLNA/F2/HTR2A/PPP3CA/TRPA1/BCL2/PTGS2	12
BP	GO:0009267	cellular response to starvation	7/232	190/18986	0.0368421052631579	3.01501814882033	3.10474103509704	0.00896377625751123	0.0247004411860288	0.012337451422001	PRKCH/HSPA5/MAP1LC3A/TP53/HSPA8/BCL2/SRD5A1	7
BP	GO:0009191	ribonucleoside diphosphate catabolic process	5/232	104/18986	0.0480769230769231	3.93443302387268	3.33748415004029	0.00902048801456427	0.0247004411860288	0.012337451422001	ALDOA/COL6A1/HTR2A/INS/LIPA	5
BP	GO:0046031	ADP metabolic process	5/232	104/18986	0.0480769230769231	3.93443302387268	3.33748415004029	0.00902048801456427	0.0247004411860288	0.012337451422001	ALDOA/COL6A1/HTR2A/INS/LIPA	5
BP	GO:0001547	antral ovarian follicle growth	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	ESR1/NPR2	2
BP	GO:0009756	carbohydrate mediated signaling	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	SMARCA4/CLEC7A	2
BP	GO:0010518	positive regulation of phospholipase activity	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	PLAA/PLA2G5	2
BP	GO:0032817	regulation of natural killer cell proliferation	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	IL12B/FCGR3A	2
BP	GO:0033629	negative regulation of cell adhesion mediated by integrin	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	PDE3B/CYP1B1	2
BP	GO:0035112	genitalia morphogenesis	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	NPR2/AR	2
BP	GO:0043589	skin morphogenesis	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	COL1A2/COL1A1	2
BP	GO:0045906	negative regulation of vasoconstriction	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	MMP2/ITGB1	2
BP	GO:0048012	hepatocyte growth factor receptor signaling pathway	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	NRP1/HGF	2
BP	GO:0048484	enteric nervous system development	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	EDNRA/SLC6A4	2
BP	GO:0048630	skeletal muscle tissue growth	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	IGF2/COL6A1	2
BP	GO:0051583	dopamine uptake involved in synaptic transmission	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	SNCA/SLC6A3	2
BP	GO:0051934	catecholamine uptake involved in synaptic transmission	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	SNCA/SLC6A3	2
BP	GO:0070528	protein kinase C signaling	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	PRKCH/PRKCZ	2
BP	GO:0071394	cellular response to testosterone stimulus	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	AR/SRD5A1	2
BP	GO:0072110	glomerular mesangial cell proliferation	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	PDGFRB/EGR1	2
BP	GO:0097048	dendritic cell apoptotic process	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	BCL2L1/BCL2	2
BP	GO:0097084	vascular associated smooth muscle cell development	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	VEGFA/EDNRA	2
BP	GO:0106014	regulation of inflammatory response to wounding	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	GRN/ALOX5	2
BP	GO:2000321	positive regulation of T-helper 17 cell differentiation	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	BRD4/IL12B	2
BP	GO:2000668	regulation of dendritic cell apoptotic process	2/232	12/18986	0.166666666666667	13.639367816092	4.8712325674904	0.00905182210909896	0.0247004411860288	0.012337451422001	BCL2L1/BCL2	2
BP	GO:0050832	defense response to fungus	4/232	67/18986	0.0597014925373134	4.88574369531652	3.54376407474089	0.00913082631594696	0.0249001360503758	0.0124371956196673	PLA2G5/IL17RA/LTF/CLEC7A	4
BP	GO:0051961	negative regulation of nervous system development	6/232	146/18986	0.0410958904109589	3.36313179026925	3.18805832857739	0.00917402389765086	0.0249860676346211	0.0124801169884905	TP53/EPHB2/F2/NRP1/TNF/PPP3CA	6
BP	GO:1903900	regulation of viral life cycle	6/232	146/18986	0.0410958904109589	3.36313179026925	3.18805832857739	0.00917402389765086	0.0249860676346211	0.0124801169884905	DDB1/CXCL8/LTF/PPIA/TNF/BCL2	6
BP	GO:0045580	regulation of T cell differentiation	7/232	191/18986	0.0366492146596859	2.99923271348619	3.08859671708826	0.0092109948127912	0.0250707917374253	0.0125224352408143	RHOA/SMARCA4/CDKN2A/BRD4/IL12B/BRAF/PRKCZ	7
BP	GO:0002027	regulation of heart rate	5/232	105/18986	0.0476190476190476	3.89696223316913	3.31075713931536	0.00937969675784621	0.0254328366116363	0.0127032705147482	PDE4D/EDNRA/MYH7/MDM2/TNF	5
BP	GO:0010906	regulation of glucose metabolic process	5/232	105/18986	0.0476190476190476	3.89696223316913	3.31075713931536	0.00937969675784621	0.0254328366116363	0.0127032705147482	DDB1/RORA/TP53/IGF2/INS	5
BP	GO:0032602	chemokine production	5/232	105/18986	0.0476190476190476	3.89696223316913	3.31075713931536	0.00937969675784621	0.0254328366116363	0.0127032705147482	EGR1/IL17RA/CLEC7A/TNF/HAVCR2	5
BP	GO:0032642	regulation of chemokine production	5/232	105/18986	0.0476190476190476	3.89696223316913	3.31075713931536	0.00937969675784621	0.0254328366116363	0.0127032705147482	EGR1/IL17RA/CLEC7A/TNF/HAVCR2	5
BP	GO:0043255	regulation of carbohydrate biosynthetic process	5/232	105/18986	0.0476190476190476	3.89696223316913	3.31075713931536	0.00937969675784621	0.0254328366116363	0.0127032705147482	SNCA/DDB1/IGF2/AP2A1/INS	5
BP	GO:1905477	positive regulation of protein localization to membrane	5/232	105/18986	0.0476190476190476	3.89696223316913	3.31075713931536	0.00937969675784621	0.0254328366116363	0.0127032705147482	ITGB1/ITGB2/PRKCH/EPHB2/TNF	5
BP	GO:0001889	liver development	6/232	147/18986	0.0408163265306122	3.3402533427164	3.16807136367294	0.00946957583421897	0.0256440191685373	0.0128087526199995	CPB2/CYP1A1/LIPA/TNF/HGF/SRD5A1	6
BP	GO:0034763	negative regulation of transmembrane transport	6/232	147/18986	0.0408163265306122	3.3402533427164	3.16807136367294	0.00946957583421897	0.0256440191685373	0.0128087526199995	CRBN/MMP9/EPHB2/TNF/PPP3CA/BCL2	6
BP	GO:0001556	oocyte maturation	3/232	36/18986	0.0833333333333333	6.81968390804598	3.88730285657817	0.00955548042895026	0.0257786967281964	0.0128760217767492	PDE3A/EDNRA/NPR2	3
BP	GO:0007617	mating behavior	3/232	36/18986	0.0833333333333333	6.81968390804598	3.88730285657817	0.00955548042895026	0.0257786967281964	0.0128760217767492	THRA/THRB/SLC6A4	3
BP	GO:0032373	positive regulation of sterol transport	3/232	36/18986	0.0833333333333333	6.81968390804598	3.88730285657817	0.00955548042895026	0.0257786967281964	0.0128760217767492	APOA1/ABCA1/PON1	3
BP	GO:0032376	positive regulation of cholesterol transport	3/232	36/18986	0.0833333333333333	6.81968390804598	3.88730285657817	0.00955548042895026	0.0257786967281964	0.0128760217767492	APOA1/ABCA1/PON1	3
BP	GO:1901797	negative regulation of signal transduction by p53 class mediator	3/232	36/18986	0.0833333333333333	6.81968390804598	3.88730285657817	0.00955548042895026	0.0257786967281964	0.0128760217767492	MDM2/BCL2/DYRK1A	3
BP	GO:1903725	regulation of phospholipid metabolic process	3/232	36/18986	0.0833333333333333	6.81968390804598	3.88730285657817	0.00955548042895026	0.0257786967281964	0.0128760217767492	PRKCD/HTR2A/PDGFA	3
BP	GO:0042058	regulation of epidermal growth factor receptor signaling pathway	4/232	68/18986	0.0588235294117647	4.81389452332657	3.50419173700378	0.00961057057522441	0.0259109708572885	0.0129420904606958	ITGA1/PDE6H/MMP9/PLAUR	4
BP	GO:0032200	telomere organization	7/232	193/18986	0.0362694300518135	2.96815258174022	3.05662175079893	0.00972037510590362	0.0261905002853459	0.0130817106688412	CDK2/PRKCQ/ATM/ATR/RPA1/TP53/LMNA	7
BP	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	5/232	106/18986	0.0471698113207547	3.86019843851659	3.28435762511409	0.0097486419068561	0.0262171023859853	0.0130949979669057	ATM/TP53/TNF/BCL2L1/BCL2	5
BP	GO:0110020	regulation of actomyosin structure organization	5/232	106/18986	0.0471698113207547	3.86019843851659	3.28435762511409	0.0097486419068561	0.0262171023859853	0.0130949979669057	RHOA/APOA1/BRAF/TGFBR1/NRP1	5
BP	GO:1901222	regulation of non-canonical NF-kappaB signal transduction	5/232	106/18986	0.0471698113207547	3.86019843851659	3.28435762511409	0.0097486419068561	0.0262171023859853	0.0130949979669057	RHOA/IL18R1/IL12B/TNF/HAVCR2	5
BP	GO:0046165	alcohol biosynthetic process	6/232	148/18986	0.0405405405405405	3.31768406337372	3.14825595338943	0.00977186412914631	0.0262630364652606	0.0131179412604042	SNCA/HMGCR/APOA1/CYP3A4/CYP2R1/LIPA	6
BP	GO:0141091	transforming growth factor beta receptor superfamily signaling pathway	11/232	397/18986	0.0277078085642317	2.26750195431252	2.83869161311847	0.0099022648164244	0.02659678665517	0.0132846438194427	KDR/EGR1/INHBA/HSPA1A/XIAP/HSPA5/HTRA1/TP53/COL1A2/COL3A1/TGFBR1	11
BP	GO:0050852	T cell receptor signaling pathway	6/232	149/18986	0.0402684563758389	3.29541772737792	3.12860931494682	0.0100809685811236	0.0270597750488917	0.0135158986692436	PDE4D/PDE4B/IKBKB/BRAF/HLA-A/LIPA	6
BP	GO:0006278	RNA-templated DNA biosynthetic process	4/232	69/18986	0.0579710144927536	4.74412793603198	3.46538451845627	0.0101064081365221	0.0270940446343376	0.0135330157459187	ATM/ATR/RPA1/TP53	4
BP	GO:0048857	neural nucleus development	4/232	69/18986	0.0579710144927536	4.74412793603198	3.46538451845627	0.0101064081365221	0.0270940446343376	0.0135330157459187	RHOA/MAOB/HSPA5/BCL2	4
BP	GO:0021543	pallium development	7/232	195/18986	0.0358974358974359	2.93770999115827	3.02505639404737	0.0102500522623089	0.0274619194696947	0.0137167629865616	NTRK2/RHOA/KCNA2/FLNA/COL3A1/LAMB1/SRD5A1	7
BP	GO:0003382	epithelial cell morphogenesis	3/232	37/18986	0.0810810810810811	6.63536812674744	3.81621068164568	0.010306355723358	0.0275093489844437	0.0137404532247147	COL18A1/COL27A1/AR	3
BP	GO:0008340	determination of adult lifespan	3/232	37/18986	0.0810810810810811	6.63536812674744	3.81621068164568	0.010306355723358	0.0275093489844437	0.0137404532247147	ATM/TP53/LIPA	3
BP	GO:0010661	positive regulation of muscle cell apoptotic process	3/232	37/18986	0.0810810810810811	6.63536812674744	3.81621068164568	0.010306355723358	0.0275093489844437	0.0137404532247147	TP53/CDKN2A/IL12B	3
BP	GO:0045773	positive regulation of axon extension	3/232	37/18986	0.0810810810810811	6.63536812674744	3.81621068164568	0.010306355723358	0.0275093489844437	0.0137404532247147	VEGFA/NRP1/MAPT	3
BP	GO:0048265	response to pain	3/232	37/18986	0.0810810810810811	6.63536812674744	3.81621068164568	0.010306355723358	0.0275093489844437	0.0137404532247147	NTRK1/COL6A1/TRPA1	3
BP	GO:1900117	regulation of execution phase of apoptosis	3/232	37/18986	0.0810810810810811	6.63536812674744	3.81621068164568	0.010306355723358	0.0275093489844437	0.0137404532247147	TP53/HTR2A/BCL2L1	3
BP	GO:0061008	hepaticobiliary system development	6/232	150/18986	0.04	3.27344827586207	3.10912872958144	0.0103969685267118	0.0277261119378569	0.0138487226433734	CPB2/CYP1A1/LIPA/TNF/HGF/SRD5A1	6
BP	GO:0006650	glycerophospholipid metabolic process	9/232	294/18986	0.0306122448979592	2.5051900070373	2.89294010885603	0.010400534038429	0.0277261119378569	0.0138487226433734	APOA1/PLA2G2A/ATM/PLA2G5/PLA2G10/HTR2A/PON1/PDGFA/ALOX15	9
BP	GO:0009134	nucleoside diphosphate catabolic process	5/232	108/18986	0.0462962962962963	3.78871328224776	3.23251158021424	0.0105162285094603	0.0280170673560451	0.0139940499397901	ALDOA/COL6A1/HTR2A/INS/LIPA	5
BP	GO:0001886	endothelial cell morphogenesis	2/232	13/18986	0.153846153846154	12.5901856763926	4.6493945652209	0.0106120561434789	0.0280450029647465	0.0140080033025136	COL18A1/COL27A1	2
BP	GO:0010269	response to selenium ion	2/232	13/18986	0.153846153846154	12.5901856763926	4.6493945652209	0.0106120561434789	0.0280450029647465	0.0140080033025136	MAOB/PTGS2	2
BP	GO:0021559	trigeminal nerve development	2/232	13/18986	0.153846153846154	12.5901856763926	4.6493945652209	0.0106120561434789	0.0280450029647465	0.0140080033025136	NRP2/NRP1	2
BP	GO:0021979	hypothalamus cell differentiation	2/232	13/18986	0.153846153846154	12.5901856763926	4.6493945652209	0.0106120561434789	0.0280450029647465	0.0140080033025136	NRP2/NRP1	2
BP	GO:0032769	negative regulation of monooxygenase activity	2/232	13/18986	0.153846153846154	12.5901856763926	4.6493945652209	0.0106120561434789	0.0280450029647465	0.0140080033025136	SNCA/GLA	2
BP	GO:0034380	high-density lipoprotein particle assembly	2/232	13/18986	0.153846153846154	12.5901856763926	4.6493945652209	0.0106120561434789	0.0280450029647465	0.0140080033025136	APOA1/ABCA1	2
BP	GO:0044406	adhesion of symbiont to host	2/232	13/18986	0.153846153846154	12.5901856763926	4.6493945652209	0.0106120561434789	0.0280450029647465	0.0140080033025136	ICAM1/LTF	2
BP	GO:0051610	serotonin uptake	2/232	13/18986	0.153846153846154	12.5901856763926	4.6493945652209	0.0106120561434789	0.0280450029647465	0.0140080033025136	SNCA/SLC6A4	2
BP	GO:0070914	UV-damage excision repair	2/232	13/18986	0.153846153846154	12.5901856763926	4.6493945652209	0.0106120561434789	0.0280450029647465	0.0140080033025136	DDB1/POLD3	2
BP	GO:0071801	regulation of podosome assembly	2/232	13/18986	0.153846153846154	12.5901856763926	4.6493945652209	0.0106120561434789	0.0280450029647465	0.0140080033025136	RHOA/TNF	2
BP	GO:0097475	motor neuron migration	2/232	13/18986	0.153846153846154	12.5901856763926	4.6493945652209	0.0106120561434789	0.0280450029647465	0.0140080033025136	VEGFA/NRP1	2
BP	GO:1903624	regulation of DNA catabolic process	2/232	13/18986	0.153846153846154	12.5901856763926	4.6493945652209	0.0106120561434789	0.0280450029647465	0.0140080033025136	ATM/CDKN2A	2
BP	GO:0046530	photoreceptor cell differentiation	4/232	70/18986	0.0571428571428571	4.67635467980296	3.42731568415259	0.0106185359681769	0.0280450029647465	0.0140080033025136	VEGFA/NTRK2/PDE6C/THRB	4
BP	GO:0046847	filopodium assembly	4/232	70/18986	0.0571428571428571	4.67635467980296	3.42731568415259	0.0106185359681769	0.0280450029647465	0.0140080033025136	PRKCD/EPHB2/TGFBR1/NRP1	4
BP	GO:0033157	regulation of intracellular protein transport	6/232	151/18986	0.0397350993377483	3.25176981045901	3.08981154065204	0.0107199428195589	0.0282778997510387	0.0141243312970453	PRKCD/CDK1/CDKN2A/FLNA/MDM2/PTGS2	6
BP	GO:0060078	regulation of postsynaptic membrane potential	6/232	151/18986	0.0397350993377483	3.25176981045901	3.08981154065204	0.0107199428195589	0.0282778997510387	0.0141243312970453	SNCA/HTR3A/KCNA2/HTR3B/PPP3CA/PRKCZ	6
BP	GO:0070588	calcium ion transmembrane transport	10/232	348/18986	0.028735632183908	2.35161514070551	2.83038395542359	0.010773880980615	0.0284026603410048	0.0141866470956375	SNCA/PDE4D/PDE4B/EDNRA/FLNA/F2/HTR2A/PPP3CA/TRPA1/BCL2	10
BP	GO:0006006	glucose metabolic process	7/232	197/18986	0.0355329949238579	2.90788552424296	2.99389062339664	0.0108004713060747	0.0284552158378162	0.0142128976748877	DDB1/RORA/TP53/IGF2/INS/LIPA/TNF	7
BP	GO:0060079	excitatory postsynaptic potential	5/232	109/18986	0.0458715596330275	3.75395444479595	3.20705088233447	0.0109151098567676	0.0287395380218832	0.0143549117833689	SNCA/HTR3A/HTR3B/PPP3CA/PRKCZ	5
BP	GO:0099173	postsynapse organization	8/232	246/18986	0.032520325203252	2.66134006167648	2.91704840257733	0.0109629893632497	0.0288478415490804	0.0144090075582404	NRP2/EPHB2/EPHB3/EPHB1/LAMA5/HSPA8/NRP1/INS	8
BP	GO:0031112	positive regulation of microtubule polymerization or depolymerization	3/232	38/18986	0.0789473684210526	6.46075317604356	3.74770151822442	0.0110905452605647	0.0290939702663649	0.0145319446778727	HSPA1A/CDKN1B/MAPT	3
BP	GO:0034391	regulation of smooth muscle cell apoptotic process	3/232	38/18986	0.0789473684210526	6.46075317604356	3.74770151822442	0.0110905452605647	0.0290939702663649	0.0145319446778727	ESR1/CDKN2A/IL12B	3
BP	GO:0042401	biogenic amine biosynthetic process	3/232	38/18986	0.0789473684210526	6.46075317604356	3.74770151822442	0.0110905452605647	0.0290939702663649	0.0145319446778727	NR4A2/SNCA/SLC6A3	3
BP	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	3/232	38/18986	0.0789473684210526	6.46075317604356	3.74770151822442	0.0110905452605647	0.0290939702663649	0.0145319446778727	BRD4/IL12B/PRKCZ	3
BP	GO:0071404	cellular response to low-density lipoprotein particle stimulus	3/232	38/18986	0.0789473684210526	6.46075317604356	3.74770151822442	0.0110905452605647	0.0290939702663649	0.0145319446778727	ITGB1/ITGB2/ABCA1	3
BP	GO:0002704	negative regulation of leukocyte mediated immunity	4/232	71/18986	0.0563380281690141	4.6104905293832	3.38995980704384	0.0111471456772896	0.0292066145319182	0.0145882085779287	MICA/HLA-A/HAVCR2/AHR	4
BP	GO:0003208	cardiac ventricle morphogenesis	4/232	71/18986	0.0563380281690141	4.6104905293832	3.38995980704384	0.0111471456772896	0.0292066145319182	0.0145882085779287	EDNRA/MYH7/COL11A1/TGFBR1	4
BP	GO:0019218	regulation of steroid metabolic process	5/232	110/18986	0.0454545454545455	3.7198275862069	3.18188932753756	0.0113242073207379	0.0296342169543913	0.0148017887352814	PDE8B/APOA1/EGR1/RORA/TNF	5
BP	GO:0097306	cellular response to alcohol	5/232	110/18986	0.0454545454545455	3.7198275862069	3.18188932753756	0.0113242073207379	0.0296342169543913	0.0148017887352814	INHBA/CYP1B1/MDM2/ABCA1/AHR	5
BP	GO:0006997	nucleus organization	6/232	153/18986	0.0392156862745098	3.20926301555105	3.05165702525959	0.011387127324209	0.0297624428107076	0.0148658353756402	PRKCA/ATR/CDK1/CDKN2A/LMNA/PLEC	6
BP	GO:2001235	positive regulation of apoptotic signaling pathway	6/232	153/18986	0.0392156862745098	3.20926301555105	3.05165702525959	0.011387127324209	0.0297624428107076	0.0148658353756402	MMP2/INHBA/PRKCD/TP53/TGFBR1/TNF	6
BP	GO:0022604	regulation of cell morphogenesis	8/232	248/18986	0.032258064516129	2.63987764182425	2.89119913424883	0.0114702416771616	0.0299613643320361	0.0149651933015857	VEGFA/KDR/PLAA/MYH9/ITGB2/ALDOA/EPHB2/F2	8
BP	GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	4/232	72/18986	0.0555555555555556	4.54645593869732	3.35329268645989	0.0116924234711565	0.0305230786096857	0.0152457600558939	SKP2/RHOA/SMARCA4/AR	4
BP	GO:0045333	cellular respiration	8/232	249/18986	0.0321285140562249	2.62927572358399	2.87836966500612	0.0117302708231571	0.0306031958754239	0.015285777271241	SNCA/NR4A3/RHOA/CDK1/CYP1A2/COL6A1/TNF/PLEC	8
BP	GO:0003279	cardiac septum development	5/232	111/18986	0.045045045045045	3.6863156259708	3.15702037598466	0.0117436370281302	0.0306193853245639	0.0152938636264931	NRP2/TP53/MDM2/TGFBR1/NRP1	5
BP	GO:0009309	amine biosynthetic process	3/232	39/18986	0.0769230769230769	6.29509283819629	3.68161179110575	0.0119082968702113	0.030897983869553	0.0154330188743349	NR4A2/SNCA/SLC6A3	3
BP	GO:0009595	detection of biotic stimulus	3/232	39/18986	0.0769230769230769	6.29509283819629	3.68161179110575	0.0119082968702113	0.030897983869553	0.0154330188743349	NR4A1/HLA-A/CLEC7A	3
BP	GO:0034390	smooth muscle cell apoptotic process	3/232	39/18986	0.0769230769230769	6.29509283819629	3.68161179110575	0.0119082968702113	0.030897983869553	0.0154330188743349	ESR1/CDKN2A/IL12B	3
BP	GO:0035633	maintenance of blood-brain barrier	3/232	39/18986	0.0769230769230769	6.29509283819629	3.68161179110575	0.0119082968702113	0.030897983869553	0.0154330188743349	VEGFA/ITGB1/PTGS2	3
BP	GO:0046471	phosphatidylglycerol metabolic process	3/232	39/18986	0.0769230769230769	6.29509283819629	3.68161179110575	0.0119082968702113	0.030897983869553	0.0154330188743349	PLA2G2A/PLA2G5/PLA2G10	3
BP	GO:0055094	response to lipoprotein particle	3/232	39/18986	0.0769230769230769	6.29509283819629	3.68161179110575	0.0119082968702113	0.030897983869553	0.0154330188743349	ITGB1/ITGB2/ABCA1	3
BP	GO:0070884	regulation of calcineurin-NFAT signaling cascade	3/232	39/18986	0.0769230769230769	6.29509283819629	3.68161179110575	0.0119082968702113	0.030897983869553	0.0154330188743349	CLEC7A/TNF/PPP3CA	3
BP	GO:0071312	cellular response to alkaloid	3/232	39/18986	0.0769230769230769	6.29509283819629	3.68161179110575	0.0119082968702113	0.030897983869553	0.0154330188743349	CCNA2/MDM2/BCL2L1	3
BP	GO:0030038	contractile actin filament bundle assembly	5/232	112/18986	0.0446428571428571	3.65340209359606	3.13243768977371	0.0121735135128059	0.0313721986899029	0.0156698811338223	RHOA/APOA1/BRAF/TGFBR1/NRP1	5
BP	GO:0032204	regulation of telomere maintenance	5/232	112/18986	0.0446428571428571	3.65340209359606	3.13243768977371	0.0121735135128059	0.0313721986899029	0.0156698811338223	PRKCQ/ATM/ATR/TP53/LMNA	5
BP	GO:0043149	stress fiber assembly	5/232	112/18986	0.0446428571428571	3.65340209359606	3.13243768977371	0.0121735135128059	0.0313721986899029	0.0156698811338223	RHOA/APOA1/BRAF/TGFBR1/NRP1	5
BP	GO:0007015	actin filament organization	12/232	465/18986	0.0258064516129032	2.1119021134594	2.6999962044439	0.012214099246413	0.0313721986899029	0.0156698811338223	TPM3/RHOA/APOA1/PRKCD/ALDOA/FLNA/BRAF/TGFBR1/NRP1/BCL2/ALOX15/PLEC	12
BP	GO:0009988	cell-cell recognition	4/232	73/18986	0.0547945205479452	4.484175720359	3.31729127272971	0.0122545501234838	0.0313721986899029	0.0156698811338223	ALDOA/EPHB1/B4GALT1/HAVCR2	4
BP	GO:0015800	acidic amino acid transport	4/232	73/18986	0.0547945205479452	4.484175720359	3.31729127272971	0.0122545501234838	0.0313721986899029	0.0156698811338223	NTRK2/SNCA/ITGB1/TNF	4
BP	GO:0045670	regulation of osteoclast differentiation	4/232	73/18986	0.0547945205479452	4.484175720359	3.31729127272971	0.0122545501234838	0.0313721986899029	0.0156698811338223	LTF/IL12B/TNF/PPP3CA	4
BP	GO:0010225	response to UV-C	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	TP53/MDM2	2
BP	GO:0014733	regulation of skeletal muscle adaptation	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	MYH7/PPP3CA	2
BP	GO:0021534	cell proliferation in hindbrain	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	RORA/SLC6A4	2
BP	GO:0021924	cell proliferation in external granule layer	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	RORA/SLC6A4	2
BP	GO:0021930	cerebellar granule cell precursor proliferation	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	RORA/SLC6A4	2
BP	GO:0031115	negative regulation of microtubule polymerization	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	SNCA/DYRK1A	2
BP	GO:0032736	positive regulation of interleukin-13 production	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	IL17RA/PRKCZ	2
BP	GO:0033700	phospholipid efflux	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	APOA1/ABCA1	2
BP	GO:0042670	retinal cone cell differentiation	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	PDE6C/THRB	2
BP	GO:0045837	negative regulation of membrane potential	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	LTF/MAPT	2
BP	GO:0060354	negative regulation of cell adhesion molecule production	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	APOA1/CXCL8	2
BP	GO:0061469	regulation of type B pancreatic cell proliferation	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	NR4A3/NR4A1	2
BP	GO:0071285	cellular response to lithium ion	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	FABP4/CDKN1B	2
BP	GO:0072683	T cell extravasation	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	ITGAL/ICAM1	2
BP	GO:1900426	positive regulation of defense response to bacterium	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	GRN/HAVCR2	2
BP	GO:1901077	regulation of relaxation of muscle	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	PDE4D/PDE4B	2
BP	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	MMP8/HSPA1A	2
BP	GO:2000105	positive regulation of DNA-templated DNA replication	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	CDC7/CDK2	2
BP	GO:2000328	regulation of T-helper 17 cell lineage commitment	2/232	14/18986	0.142857142857143	11.6908866995074	4.45065083577995	0.012281819599368	0.0313721986899029	0.0156698811338223	BRD4/IL12B	2
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	8/232	252/18986	0.0317460317460317	2.59797482211275	2.84025466632214	0.012536458266982	0.0320035197311134	0.0159852152859114	HSPA1A/ALDOA/MYH7/COL6A1/HTR2A/HSPA8/INS/LIPA	8
BP	GO:1905954	positive regulation of lipid localization	5/232	113/18986	0.0442477876106195	3.62107110161733	3.10813512494406	0.0126139496814583	0.0321821293782312	0.0160744277752034	APOA1/PRKCD/PLA2G10/ABCA1/PON1	5
BP	GO:0032885	regulation of polysaccharide biosynthetic process	3/232	40/18986	0.075	6.13771551724138	3.6177922126962	0.0127598333903552	0.0324768140340231	0.0162216177625506	IGF2/AP2A1/INS	3
BP	GO:0045745	positive regulation of G protein-coupled receptor signaling pathway	3/232	40/18986	0.075	6.13771551724138	3.6177922126962	0.0127598333903552	0.0324768140340231	0.0162216177625506	PDE6H/PRKCA/F2	3
BP	GO:0072539	T-helper 17 cell differentiation	3/232	40/18986	0.075	6.13771551724138	3.6177922126962	0.0127598333903552	0.0324768140340231	0.0162216177625506	RORA/BRD4/IL12B	3
BP	GO:0106056	regulation of calcineurin-mediated signaling	3/232	40/18986	0.075	6.13771551724138	3.6177922126962	0.0127598333903552	0.0324768140340231	0.0162216177625506	CLEC7A/TNF/PPP3CA	3
BP	GO:0034767	positive regulation of monoatomic ion transmembrane transport	6/232	157/18986	0.0382165605095541	3.12749835273446	2.97719834107741	0.0128085997127108	0.0325815421603518	0.0162739276853316	SNCA/EDNRA/EPHB2/FLNA/F2/PPP3CA	6
BP	GO:0032732	positive regulation of interleukin-1 production	4/232	74/18986	0.0540540540540541	4.42357875116496	3.28193359740073	0.0128337009452221	0.0325872358917873	0.0162767716076108	EGR1/CLEC7A/TNF/HAVCR2	4
BP	GO:0042130	negative regulation of T cell proliferation	4/232	74/18986	0.0540540540540541	4.42357875116496	3.28193359740073	0.0128337009452221	0.0325872358917873	0.0162767716076108	PDE5A/PLA2G5/CDKN2A/HAVCR2	4
BP	GO:0071806	protein transmembrane transport	4/232	74/18986	0.0540540540540541	4.42357875116496	3.28193359740073	0.0128337009452221	0.0325872358917873	0.0162767716076108	EDNRA/HSPA5/ABCA1/HSPA8	4
BP	GO:0042552	myelination	6/232	158/18986	0.0379746835443038	3.10770405936272	2.95895539204481	0.0131825575337973	0.0334531845783484	0.0167092982889737	HEXA/NTRK2/COL6A1/RAF1/TNF/PLEC	6
BP	GO:0010833	telomere maintenance via telomere lengthening	4/232	75/18986	0.0533333333333333	4.36459770114943	3.24719870857147	0.013430045759863	0.0340206609414538	0.016992743107235	ATM/ATR/RPA1/TP53	4
BP	GO:1901184	regulation of ERBB signaling pathway	4/232	75/18986	0.0533333333333333	4.36459770114943	3.24719870857147	0.013430045759863	0.0340206609414538	0.016992743107235	ITGA1/PDE6H/MMP9/PLAUR	4
BP	GO:1904888	cranial skeletal system development	4/232	75/18986	0.0533333333333333	4.36459770114943	3.24719870857147	0.013430045759863	0.0340206609414538	0.016992743107235	PDGFRA/EDNRA/MMP14/TGFBR1	4
BP	GO:0045445	myoblast differentiation	5/232	115/18986	0.0434782608695652	3.55809595202399	3.06034670799116	0.0135269443638814	0.0342458342806139	0.0171052133709235	ITGB1/SMARCA4/TNF/PLG/PLEC	5
BP	GO:0007043	cell-cell junction assembly	6/232	159/18986	0.0377358490566038	3.08815875081327	2.94085661670333	0.0135641007420354	0.0343195827058837	0.0171420494584801	PRKCA/RHOA/PRKCH/IKBKB/EPHB2/TNF	6
BP	GO:0002478	antigen processing and presentation of exogenous peptide antigen	3/232	41/18986	0.0731707317073171	5.98801513877208	3.55610621220184	0.0136453534027747	0.0344233222125454	0.0171938655825057	IKBKB/LNPEP/HLA-A	3
BP	GO:0003203	endocardial cushion morphogenesis	3/232	41/18986	0.0731707317073171	5.98801513877208	3.55610621220184	0.0136453534027747	0.0344233222125454	0.0171938655825057	MDM2/ADAMTS5/TGFBR1	3
BP	GO:0097242	amyloid-beta clearance	3/232	41/18986	0.0731707317073171	5.98801513877208	3.55610621220184	0.0136453534027747	0.0344233222125454	0.0171938655825057	HMGCR/ITGB2/TNF	3
BP	GO:1900016	negative regulation of cytokine production involved in inflammatory response	3/232	41/18986	0.0731707317073171	5.98801513877208	3.55610621220184	0.0136453534027747	0.0344233222125454	0.0171938655825057	PLA2G10/EPHB2/F2	3
BP	GO:1990806	ligand-gated ion channel signaling pathway	3/232	41/18986	0.0731707317073171	5.98801513877208	3.55610621220184	0.0136453534027747	0.0344233222125454	0.0171938655825057	HTR3A/HTR3B/F2	3
BP	GO:0032271	regulation of protein polymerization	7/232	207/18986	0.0338164251207729	2.76740796268532	2.84372821095714	0.0138790583235623	0.0349494049633007	0.0174566349934856	SNCA/PRKCD/HSPA1A/CDKN1B/MAPT/ALOX15/DYRK1A	7
BP	GO:0007272	ensheathment of neurons	6/232	160/18986	0.0375	3.06885775862069	2.92289984265531	0.0139533029548748	0.0349494049633007	0.0174566349934856	HEXA/NTRK2/COL6A1/RAF1/TNF/PLEC	6
BP	GO:0008366	axon ensheathment	6/232	160/18986	0.0375	3.06885775862069	2.92289984265531	0.0139533029548748	0.0349494049633007	0.0174566349934856	HEXA/NTRK2/COL6A1/RAF1/TNF/PLEC	6
BP	GO:0002444	myeloid leukocyte mediated immunity	5/232	116/18986	0.0431034482758621	3.52742271105826	3.03684947095069	0.0139997202624992	0.0349494049633007	0.0174566349934856	NR4A3/ITGB2/FCGR2A/F2/FCGR3A	5
BP	GO:0009135	purine nucleoside diphosphate metabolic process	5/232	116/18986	0.0431034482758621	3.52742271105826	3.03684947095069	0.0139997202624992	0.0349494049633007	0.0174566349934856	ALDOA/COL6A1/HTR2A/INS/LIPA	5
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	5/232	116/18986	0.0431034482758621	3.52742271105826	3.03684947095069	0.0139997202624992	0.0349494049633007	0.0174566349934856	ALDOA/COL6A1/HTR2A/INS/LIPA	5
BP	GO:2001252	positive regulation of chromosome organization	5/232	116/18986	0.0431034482758621	3.52742271105826	3.03684947095069	0.0139997202624992	0.0349494049633007	0.0174566349934856	CDK2/PRKCQ/ATM/ATR/CDK1	5
BP	GO:0090307	mitotic spindle assembly	4/232	76/18986	0.0526315789473684	4.30716878402904	3.21306661090011	0.0140437488830416	0.0349494049633007	0.0174566349934856	RHOA/HSPA1A/TPX2/FLNA	4
BP	GO:0001787	natural killer cell proliferation	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	IL12B/FCGR3A	2
BP	GO:0006521	regulation of cellular amino acid metabolic process	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	INS/HNF4A	2
BP	GO:0007567	parturition	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	MMP2/CYP1A1	2
BP	GO:0033189	response to vitamin A	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	CYP1A1/LIPA	2
BP	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	PDGFRB/PDGFA	2
BP	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	MDM2/DYRK1A	2
BP	GO:0050930	induction of positive chemotaxis	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	VEGFA/CXCL8	2
BP	GO:0055012	ventricular cardiac muscle cell differentiation	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	CDK1/LMNA	2
BP	GO:0060009	Sertoli cell development	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	NTRK1/FLNA	2
BP	GO:0060033	anatomical structure regression	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	FLT1/SLC6A3	2
BP	GO:0070341	fat cell proliferation	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	COL6A1/LIPA	2
BP	GO:0070424	regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	HSPA1A/XIAP	2
BP	GO:0072537	fibroblast activation	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	IL17RA/MDM2	2
BP	GO:1900119	positive regulation of execution phase of apoptosis	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	TP53/HTR2A	2
BP	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	HSPA1A/BCL2L1	2
BP	GO:2000671	regulation of motor neuron apoptotic process	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	RHOA/BCL2	2
BP	GO:2001028	positive regulation of endothelial cell chemotaxis	2/232	15/18986	0.133333333333333	10.9114942528736	4.27112211388753	0.0140582265053501	0.0349494049633007	0.0174566349934856	VEGFA/KDR	2
BP	GO:0009199	ribonucleoside triphosphate metabolic process	8/232	258/18986	0.0310077519379845	2.53755680299385	2.76565280819589	0.014269916037752	0.0354344721123274	0.017698917807078	HSPA1A/ALDOA/MYH7/COL6A1/HTR2A/HSPA8/INS/LIPA	8
BP	GO:0051924	regulation of calcium ion transport	8/232	258/18986	0.0310077519379845	2.53755680299385	2.76565280819589	0.014269916037752	0.0354344721123274	0.017698917807078	SNCA/PDE4D/PDE4B/PDGFRB/F2/PPP3CA/BCL2/PTGS2	8
BP	GO:0006766	vitamin metabolic process	5/232	117/18986	0.0427350427350427	3.49727379899794	3.01360957197011	0.0144834905540807	0.0359439382526113	0.0179533875029659	CYP3A4/CYP1A1/CYP2R1/LIPA/TNF	5
BP	GO:0006476	protein deacetylation	3/232	42/18986	0.0714285714285714	5.84544334975369	3.49642857117766	0.0145650319522196	0.0360625805603307	0.0180126473233496	FLNA/MAPT/DYRK1A	3
BP	GO:0051955	regulation of amino acid transport	3/232	42/18986	0.0714285714285714	5.84544334975369	3.49642857117766	0.0145650319522196	0.0360625805603307	0.0180126473233496	SNCA/ITGB1/TNF	3
BP	GO:0060251	regulation of glial cell proliferation	3/232	42/18986	0.0714285714285714	5.84544334975369	3.49642857117766	0.0145650319522196	0.0360625805603307	0.0180126473233496	PRKCH/TP53/TNF	3
BP	GO:0070232	regulation of T cell apoptotic process	3/232	42/18986	0.0714285714285714	5.84544334975369	3.49642857117766	0.0145650319522196	0.0360625805603307	0.0180126473233496	PRKCQ/TP53/BCL2	3
BP	GO:0009144	purine nucleoside triphosphate metabolic process	8/232	259/18986	0.0308880308880309	2.52775928637998	2.75342370065845	0.014574988713141	0.0360663493850642	0.01801452978738	HSPA1A/ALDOA/MYH7/COL6A1/HTR2A/HSPA8/INS/LIPA	8
BP	GO:0032371	regulation of sterol transport	4/232	77/18986	0.051948051948052	4.2512315270936	3.17951820989411	0.0146749691062975	0.0362089832074599	0.0180857729624184	APOA1/PLA2G10/ABCA1/PON1	4
BP	GO:0032374	regulation of cholesterol transport	4/232	77/18986	0.051948051948052	4.2512315270936	3.17951820989411	0.0146749691062975	0.0362089832074599	0.0180857729624184	APOA1/PLA2G10/ABCA1/PON1	4
BP	GO:0045669	positive regulation of osteoblast differentiation	4/232	77/18986	0.051948051948052	4.2512315270936	3.17951820989411	0.0146749691062975	0.0362089832074599	0.0180857729624184	VEGFA/LTF/PPP3CA/HGF	4
BP	GO:0051966	regulation of synaptic transmission, glutamatergic	4/232	77/18986	0.051948051948052	4.2512315270936	3.17951820989411	0.0146749691062975	0.0362089832074599	0.0180857729624184	NTRK1/HTR2A/TNF/PTGS2	4
BP	GO:0120192	tight junction assembly	4/232	77/18986	0.051948051948052	4.2512315270936	3.17951820989411	0.0146749691062975	0.0362089832074599	0.0180857729624184	PRKCH/IKBKB/EPHB2/TNF	4
BP	GO:0042177	negative regulation of protein catabolic process	5/232	118/18986	0.0423728813559322	3.46763588544711	2.99062172959516	0.0149783595346452	0.0368937012500822	0.0184277780110327	SNCA/HMGCR/CTSA/FLNA/INS	5
BP	GO:0045833	negative regulation of lipid metabolic process	5/232	118/18986	0.0423728813559322	3.46763588544711	2.99062172959516	0.0149783595346452	0.0368937012500822	0.0184277780110327	PDE3B/PDE8B/PDGFA/INS/TNF	5
BP	GO:1904659	D-glucose transmembrane transport	5/232	118/18986	0.0423728813559322	3.46763588544711	2.99062172959516	0.0149783595346452	0.0368937012500822	0.0184277780110327	NR4A3/EDNRA/BRAF/INS/TNF	5
BP	GO:0009620	response to fungus	4/232	78/18986	0.0512820512820513	4.19672855879752	3.14653526012384	0.0153238596848433	0.0377012796388894	0.0188311497187008	PLA2G5/IL17RA/LTF/CLEC7A	4
BP	GO:0032890	regulation of organic acid transport	4/232	78/18986	0.0512820512820513	4.19672855879752	3.14653526012384	0.0153238596848433	0.0377012796388894	0.0188311497187008	SNCA/ITGB1/PLA2G10/TNF	4
BP	GO:0022037	metencephalon development	5/232	119/18986	0.0420168067226891	3.43849608809041	2.96788081570471	0.0154844296908694	0.037984736613983	0.0189727316699748	RORA/HSPA5/TP53/HSPA8/BCL2	5
BP	GO:0099565	chemical synaptic transmission, postsynaptic	5/232	119/18986	0.0420168067226891	3.43849608809041	2.96788081570471	0.0154844296908694	0.037984736613983	0.0189727316699748	SNCA/HTR3A/HTR3B/PPP3CA/PRKCZ	5
BP	GO:0001649	osteoblast differentiation	8/232	262/18986	0.0305343511450382	2.4988154777573	2.71707631087773	0.0155187067130442	0.037984736613983	0.0189727316699748	VEGFA/IGF2/LTF/COL1A1/COL6A1/TNF/PPP3CA/HGF	8
BP	GO:0007595	lactation	3/232	43/18986	0.0697674418604651	5.70950280673617	3.43864423412266	0.0155190212499131	0.037984736613983	0.0189727316699748	VEGFA/DDR1/SLC6A3	3
BP	GO:0009409	response to cold	3/232	43/18986	0.0697674418604651	5.70950280673617	3.43864423412266	0.0155190212499131	0.037984736613983	0.0189727316699748	THRA/LIPA/TRPA1	3
BP	GO:0030866	cortical actin cytoskeleton organization	3/232	43/18986	0.0697674418604651	5.70950280673617	3.43864423412266	0.0155190212499131	0.037984736613983	0.0189727316699748	IKBKB/TNF/PLEC	3
BP	GO:0031111	negative regulation of microtubule polymerization or depolymerization	3/232	43/18986	0.0697674418604651	5.70950280673617	3.43864423412266	0.0155190212499131	0.037984736613983	0.0189727316699748	SNCA/TPX2/DYRK1A	3
BP	GO:0045761	regulation of adenylate cyclase activity	3/232	43/18986	0.0697674418604651	5.70950280673617	3.43864423412266	0.0155190212499131	0.037984736613983	0.0189727316699748	EDNRA/RAF1/ADORA3	3
BP	GO:0046640	regulation of alpha-beta T cell proliferation	3/232	43/18986	0.0697674418604651	5.70950280673617	3.43864423412266	0.0155190212499131	0.037984736613983	0.0189727316699748	PRKCQ/IL12B/HLA-A	3
BP	GO:0030010	establishment of cell polarity	6/232	164/18986	0.0365853658536585	2.99400756938604	2.85245091243066	0.0155881501943208	0.0381103088798832	0.019035452886929	RHOA/MYH9/ITGB1/EPHB1/LAMA1/PRKCZ	6
BP	GO:0051017	actin filament bundle assembly	6/232	164/18986	0.0365853658536585	2.99400756938604	2.85245091243066	0.0155881501943208	0.0381103088798832	0.019035452886929	RHOA/APOA1/FLNA/BRAF/TGFBR1/NRP1	6
BP	GO:0000209	protein polyubiquitination	8/232	263/18986	0.0304182509505703	2.48931427822211	2.70507210607093	0.015842909938313	0.0386134780916682	0.0192867773738355	PLAA/SKP2/XIAP/CDKN2A/MDM2/LNPEP/PPIA/BCL2	8
BP	GO:0001771	immunological synapse formation	2/232	16/18986	0.125	10.229525862069	4.10778830681186	0.0159384445350314	0.0386134780916682	0.0192867773738355	EPHB1/HAVCR2	2
BP	GO:0002486	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	2/232	16/18986	0.125	10.229525862069	4.10778830681186	0.0159384445350314	0.0386134780916682	0.0192867773738355	MICA/HLA-A	2
BP	GO:0009313	oligosaccharide catabolic process	2/232	16/18986	0.125	10.229525862069	4.10778830681186	0.0159384445350314	0.0386134780916682	0.0192867773738355	MAN2B1/MANBA	2
BP	GO:0010226	response to lithium ion	2/232	16/18986	0.125	10.229525862069	4.10778830681186	0.0159384445350314	0.0386134780916682	0.0192867773738355	FABP4/CDKN1B	2
BP	GO:0010958	regulation of amino acid import across plasma membrane	2/232	16/18986	0.125	10.229525862069	4.10778830681186	0.0159384445350314	0.0386134780916682	0.0192867773738355	ITGB1/TNF	2
BP	GO:0034638	phosphatidylcholine catabolic process	2/232	16/18986	0.125	10.229525862069	4.10778830681186	0.0159384445350314	0.0386134780916682	0.0192867773738355	PLA2G5/PLA2G10	2
BP	GO:0035729	cellular response to hepatocyte growth factor stimulus	2/232	16/18986	0.125	10.229525862069	4.10778830681186	0.0159384445350314	0.0386134780916682	0.0192867773738355	NRP1/HGF	2
BP	GO:0048148	behavioral response to cocaine	2/232	16/18986	0.125	10.229525862069	4.10778830681186	0.0159384445350314	0.0386134780916682	0.0192867773738355	HTR2A/SLC6A4	2
BP	GO:0060046	regulation of acrosome reaction	2/232	16/18986	0.125	10.229525862069	4.10778830681186	0.0159384445350314	0.0386134780916682	0.0192867773738355	PLA2G10/B4GALT1	2
BP	GO:0061043	regulation of vascular wound healing	2/232	16/18986	0.125	10.229525862069	4.10778830681186	0.0159384445350314	0.0386134780916682	0.0192867773738355	TNF/ALOX5	2
BP	GO:0090336	positive regulation of brown fat cell differentiation	2/232	16/18986	0.125	10.229525862069	4.10778830681186	0.0159384445350314	0.0386134780916682	0.0192867773738355	INS/PTGS2	2
BP	GO:1902946	protein localization to early endosome	2/232	16/18986	0.125	10.229525862069	4.10778830681186	0.0159384445350314	0.0386134780916682	0.0192867773738355	VEGFA/NRP1	2
BP	GO:1903727	positive regulation of phospholipid metabolic process	2/232	16/18986	0.125	10.229525862069	4.10778830681186	0.0159384445350314	0.0386134780916682	0.0192867773738355	PRKCD/HTR2A	2
BP	GO:1903789	regulation of amino acid transmembrane transport	2/232	16/18986	0.125	10.229525862069	4.10778830681186	0.0159384445350314	0.0386134780916682	0.0192867773738355	ITGB1/TNF	2
BP	GO:2001138	regulation of phospholipid transport	2/232	16/18986	0.125	10.229525862069	4.10778830681186	0.0159384445350314	0.0386134780916682	0.0192867773738355	APOA1/PRKCD	2
BP	GO:0018107	peptidyl-threonine phosphorylation	4/232	79/18986	0.0506329113924051	4.14360541248363	3.11410031703752	0.0159905683292014	0.0386818801672017	0.0193209430503797	PRKCA/PRKCD/CDK1/DYRK1A	4
BP	GO:0019731	antibacterial humoral response	4/232	79/18986	0.0506329113924051	4.14360541248363	3.11410031703752	0.0159905683292014	0.0386818801672017	0.0193209430503797	LTF/FGA/FGB/HLA-A	4
BP	GO:0007006	mitochondrial membrane organization	5/232	120/18986	0.0416666666666667	3.40984195402299	2.94538184979746	0.0160018016735722	0.0386818801672017	0.0193209430503797	SNCA/HSPA1A/TP53/BCL2L1/BCL2	5
BP	GO:0007626	locomotory behavior	7/232	213/18986	0.0328638497652582	2.68945280880686	2.75785459168389	0.0160028638951777	0.0386818801672017	0.0193209430503797	HEXA/NR4A2/SNCA/CRBN/EGR1/GLA/SLC6A3	7
BP	GO:0006865	amino acid transport	6/232	165/18986	0.0363636363636364	2.97586206896552	2.83517314252406	0.0160167274426908	0.0386935178220033	0.0193267558615638	NTRK2/SNCA/ITGB1/TNF/SLC6A4/SLC6A3	6
BP	GO:0010828	positive regulation of D-glucose transmembrane transport	3/232	44/18986	0.0681818181818182	5.57974137931035	3.38264726816326	0.0165074513615993	0.0397328474357831	0.0198458833753148	NR4A3/BRAF/INS	3
BP	GO:0035794	positive regulation of mitochondrial membrane permeability	3/232	44/18986	0.0681818181818182	5.57974137931035	3.38264726816326	0.0165074513615993	0.0397328474357831	0.0198458833753148	HSPA1A/TP53/BCL2L1	3
BP	GO:0046006	regulation of activated T cell proliferation	3/232	44/18986	0.0681818181818182	5.57974137931035	3.38264726816326	0.0165074513615993	0.0397328474357831	0.0198458833753148	IGF2/IL12B/PPP3CA	3
BP	GO:0051084	'de novo' post-translational protein folding	3/232	44/18986	0.0681818181818182	5.57974137931035	3.38264726816326	0.0165074513615993	0.0397328474357831	0.0198458833753148	HSPA1A/HSPA5/HSPA8	3
BP	GO:0070328	triglyceride homeostasis	3/232	44/18986	0.0681818181818182	5.57974137931035	3.38264726816326	0.0165074513615993	0.0397328474357831	0.0198458833753148	APOA1/RORA/HNF4A	3
BP	GO:0007088	regulation of mitotic nuclear division	5/232	121/18986	0.0413223140495868	3.38166144200627	2.9231199935375	0.0165305742722774	0.0397328474357831	0.0198458833753148	PDGFRB/ATM/IGF2/INS/TNF	5
BP	GO:0008645	hexose transmembrane transport	5/232	121/18986	0.0413223140495868	3.38166144200627	2.9231199935375	0.0165305742722774	0.0397328474357831	0.0198458833753148	NR4A3/EDNRA/BRAF/INS/TNF	5
BP	GO:0034341	response to type II interferon	5/232	121/18986	0.0413223140495868	3.38166144200627	2.9231199935375	0.0165305742722774	0.0397328474357831	0.0198458833753148	SNCA/TP53/IL12B/RAF1/TNF	5
BP	GO:0051224	negative regulation of protein transport	5/232	121/18986	0.0413223140495868	3.38166144200627	2.9231199935375	0.0165305742722774	0.0397328474357831	0.0198458833753148	HMGCR/PDE8B/IL12B/INS/PPP3CA	5
BP	GO:0014032	neural crest cell development	4/232	80/18986	0.05	4.09181034482759	3.08219669208467	0.0166752372005672	0.0399906417664752	0.0199746472709808	EDNRA/NRP2/LAMA5/NRP1	4
BP	GO:0035914	skeletal muscle cell differentiation	4/232	80/18986	0.05	4.09181034482759	3.08219669208467	0.0166752372005672	0.0399906417664752	0.0199746472709808	EGR1/EPHB1/NR4A1/COL6A1	4
BP	GO:0043297	apical junction assembly	4/232	80/18986	0.05	4.09181034482759	3.08219669208467	0.0166752372005672	0.0399906417664752	0.0199746472709808	RHOA/PRKCH/IKBKB/TNF	4
BP	GO:0046637	regulation of alpha-beta T cell differentiation	4/232	80/18986	0.05	4.09181034482759	3.08219669208467	0.0166752372005672	0.0399906417664752	0.0199746472709808	RHOA/BRD4/IL12B/PRKCZ	4
BP	GO:1902850	microtubule cytoskeleton organization involved in mitosis	6/232	167/18986	0.0359281437125748	2.94022300227132	2.80100543063372	0.0168982082303448	0.0405026560498624	0.0202303897211292	RHOA/ITGB1/HSPA1A/CDK1/TPX2/FLNA	6
BP	GO:0045582	positive regulation of T cell differentiation	5/232	122/18986	0.040983606557377	3.35394290559638	2.9010905455449	0.0170708443908457	0.0408935185519643	0.0204256189114114	RHOA/SMARCA4/BRD4/IL12B/PRKCZ	5
BP	GO:0051963	regulation of synapse assembly	6/232	168/18986	0.0357142857142857	2.92272167487685	2.78411178235115	0.0173512480387138	0.0415130393531533	0.0207350590437566	NTRK1/NTRK2/SNCA/EPHB2/EPHB3/EPHB1	6
BP	GO:0061572	actin filament bundle organization	6/232	168/18986	0.0357142857142857	2.92272167487685	2.78411178235115	0.0173512480387138	0.0415130393531533	0.0207350590437566	RHOA/APOA1/FLNA/BRAF/TGFBR1/NRP1	6
BP	GO:0031397	negative regulation of protein ubiquitination	4/232	81/18986	0.0493827160493827	4.04129416773095	3.05080841088262	0.0173780029097625	0.0415130393531533	0.0207350590437566	PLAA/HSPA1A/CDKN2A/PPIA	4
BP	GO:0070897	transcription preinitiation complex assembly	4/232	81/18986	0.0493827160493827	4.04129416773095	3.05080841088262	0.0173780029097625	0.0415130393531533	0.0207350590437566	ESR1/THRA/SMARCA4/TP53	4
BP	GO:2000027	regulation of animal organ morphogenesis	4/232	81/18986	0.0493827160493827	4.04129416773095	3.05080841088262	0.0173780029097625	0.0415130393531533	0.0207350590437566	VEGFA/PDGFA/TNF/HGF	4
BP	GO:0010463	mesenchymal cell proliferation	3/232	45/18986	0.0666666666666667	5.45574712643678	3.32833995021244	0.0175304308804303	0.0416908356199778	0.0208238652633881	KDR/LMNA/PDGFA	3
BP	GO:0010712	regulation of collagen metabolic process	3/232	45/18986	0.0666666666666667	5.45574712643678	3.32833995021244	0.0175304308804303	0.0416908356199778	0.0208238652633881	ITGB1/INHBA/F2	3
BP	GO:0019098	reproductive behavior	3/232	45/18986	0.0666666666666667	5.45574712643678	3.32833995021244	0.0175304308804303	0.0416908356199778	0.0208238652633881	THRA/THRB/SLC6A4	3
BP	GO:0021879	forebrain neuron differentiation	3/232	45/18986	0.0666666666666667	5.45574712643678	3.32833995021244	0.0175304308804303	0.0416908356199778	0.0208238652633881	INHBA/NRP2/NRP1	3
BP	GO:0048701	embryonic cranial skeleton morphogenesis	3/232	45/18986	0.0666666666666667	5.45574712643678	3.32833995021244	0.0175304308804303	0.0416908356199778	0.0208238652633881	PDGFRA/MMP14/TGFBR1	3
BP	GO:0051602	response to electrical stimulus	3/232	45/18986	0.0666666666666667	5.45574712643678	3.32833995021244	0.0175304308804303	0.0416908356199778	0.0208238652633881	NTRK1/MMP2/NR4A1	3
BP	GO:0055090	acylglycerol homeostasis	3/232	45/18986	0.0666666666666667	5.45574712643678	3.32833995021244	0.0175304308804303	0.0416908356199778	0.0208238652633881	APOA1/RORA/HNF4A	3
BP	GO:1904646	cellular response to amyloid-beta	3/232	45/18986	0.0666666666666667	5.45574712643678	3.32833995021244	0.0175304308804303	0.0416908356199778	0.0208238652633881	ICAM1/EPHB2/TNF	3
BP	GO:0030301	cholesterol transport	5/232	123/18986	0.040650406504065	3.3266750770956	2.87928893641849	0.0176227070241686	0.0418637195751917	0.020910217866689	APOA1/PLA2G10/ABCA1/PON1/LIPA	5
BP	GO:0072009	nephron epithelium development	5/232	123/18986	0.040650406504065	3.3266750770956	2.87928893641849	0.0176227070241686	0.0418637195751917	0.020910217866689	VEGFA/EDNRA/LAMA5/LAMB2/BCL2	5
BP	GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	2/232	17/18986	0.117647058823529	9.62778904665314	3.95825799494044	0.017919694136225	0.0422174171495858	0.0210868838059449	MICA/HLA-A	2
BP	GO:0002484	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway	2/232	17/18986	0.117647058823529	9.62778904665314	3.95825799494044	0.017919694136225	0.0422174171495858	0.0210868838059449	MICA/HLA-A	2
BP	GO:0010455	positive regulation of cell fate commitment	2/232	17/18986	0.117647058823529	9.62778904665314	3.95825799494044	0.017919694136225	0.0422174171495858	0.0210868838059449	BRD4/IL12B	2
BP	GO:0021783	preganglionic parasympathetic fiber development	2/232	17/18986	0.117647058823529	9.62778904665314	3.95825799494044	0.017919694136225	0.0422174171495858	0.0210868838059449	NRP2/NRP1	2
BP	GO:0042448	progesterone metabolic process	2/232	17/18986	0.117647058823529	9.62778904665314	3.95825799494044	0.017919694136225	0.0422174171495858	0.0210868838059449	EGR1/SRD5A1	2
BP	GO:0043117	positive regulation of vascular permeability	2/232	17/18986	0.117647058823529	9.62778904665314	3.95825799494044	0.017919694136225	0.0422174171495858	0.0210868838059449	VEGFA/PDE3A	2
BP	GO:0045198	establishment of epithelial cell apical/basal polarity	2/232	17/18986	0.117647058823529	9.62778904665314	3.95825799494044	0.017919694136225	0.0422174171495858	0.0210868838059449	RHOA/LAMA1	2
BP	GO:0045651	positive regulation of macrophage differentiation	2/232	17/18986	0.117647058823529	9.62778904665314	3.95825799494044	0.017919694136225	0.0422174171495858	0.0210868838059449	PRKCA/PF4	2
BP	GO:0045725	positive regulation of glycogen biosynthetic process	2/232	17/18986	0.117647058823529	9.62778904665314	3.95825799494044	0.017919694136225	0.0422174171495858	0.0210868838059449	IGF2/INS	2
BP	GO:0048841	regulation of axon extension involved in axon guidance	2/232	17/18986	0.117647058823529	9.62778904665314	3.95825799494044	0.017919694136225	0.0422174171495858	0.0210868838059449	VEGFA/NRP1	2
BP	GO:0072109	glomerular mesangium development	2/232	17/18986	0.117647058823529	9.62778904665314	3.95825799494044	0.017919694136225	0.0422174171495858	0.0210868838059449	PDGFRB/EGR1	2
BP	GO:0080154	regulation of fertilization	2/232	17/18986	0.117647058823529	9.62778904665314	3.95825799494044	0.017919694136225	0.0422174171495858	0.0210868838059449	MYH9/PLAT	2
BP	GO:0098712	L-glutamate import across plasma membrane	2/232	17/18986	0.117647058823529	9.62778904665314	3.95825799494044	0.017919694136225	0.0422174171495858	0.0210868838059449	ITGB1/TNF	2
BP	GO:1901334	lactone metabolic process	2/232	17/18986	0.117647058823529	9.62778904665314	3.95825799494044	0.017919694136225	0.0422174171495858	0.0210868838059449	PON1/PON2	2
BP	GO:2000345	regulation of hepatocyte proliferation	2/232	17/18986	0.117647058823529	9.62778904665314	3.95825799494044	0.017919694136225	0.0422174171495858	0.0210868838059449	CPB2/TNF	2
BP	GO:0003151	outflow tract morphogenesis	4/232	82/18986	0.0487804878048781	3.99201009251472	3.01992017418481	0.0180989965196486	0.0425694769626058	0.021262731711173	VEGFA/EDNRA/NRP2/NRP1	4
BP	GO:0042246	tissue regeneration	4/232	82/18986	0.0487804878048781	3.99201009251472	3.01992017418481	0.0180989965196486	0.0425694769626058	0.021262731711173	CDKN1B/COL6A1/PPP3CA/PLG	4
BP	GO:0061333	renal tubule morphogenesis	4/232	82/18986	0.0487804878048781	3.99201009251472	3.01992017418481	0.0180989965196486	0.0425694769626058	0.021262731711173	VEGFA/COL4A1/LAMA5/BCL2	4
BP	GO:0015749	monosaccharide transmembrane transport	5/232	124/18986	0.0403225806451613	3.29984705228031	2.85771072397849	0.0181862552359124	0.0427511970251575	0.0213534978002177	NR4A3/EDNRA/BRAF/INS/TNF	5
BP	GO:0007204	positive regulation of cytosolic calcium ion concentration	6/232	170/18986	0.0352941176470588	2.88833671399594	2.75069591716603	0.0182822611243733	0.0429532684438574	0.021454429046474	EDNRA/ESR1/HTR2A/CXCR1/CXCR2/BCL2	6
BP	GO:0071805	potassium ion transmembrane transport	7/232	219/18986	0.0319634703196347	2.61576917020942	2.67489220440752	0.0183478670531312	0.0430837339479346	0.0215195943529022	CRBN/ITGB1/KCNA2/KCNQ2/KCNQ5/KCNQ4/FLNA	7
BP	GO:0008038	neuron recognition	3/232	46/18986	0.0652173913043478	5.33714392803598	3.27563196353	0.0185880475849786	0.0434805752042497	0.0217178098295068	EPHB2/EPHB3/NRP1	3
BP	GO:0021762	substantia nigra development	3/232	46/18986	0.0652173913043478	5.33714392803598	3.27563196353	0.0185880475849786	0.0434805752042497	0.0217178098295068	RHOA/MAOB/HSPA5	3
BP	GO:0030149	sphingolipid catabolic process	3/232	46/18986	0.0652173913043478	5.33714392803598	3.27563196353	0.0185880475849786	0.0434805752042497	0.0217178098295068	HEXA/PRKCD/GLA	3
BP	GO:0045601	regulation of endothelial cell differentiation	3/232	46/18986	0.0652173913043478	5.33714392803598	3.27563196353	0.0185880475849786	0.0434805752042497	0.0217178098295068	VEGFA/IKBKB/TNF	3
BP	GO:0046633	alpha-beta T cell proliferation	3/232	46/18986	0.0652173913043478	5.33714392803598	3.27563196353	0.0185880475849786	0.0434805752042497	0.0217178098295068	PRKCQ/IL12B/HLA-A	3
BP	GO:0048512	circadian behavior	3/232	46/18986	0.0652173913043478	5.33714392803598	3.27563196353	0.0185880475849786	0.0434805752042497	0.0217178098295068	KCNA2/EGR1/TP53	3
BP	GO:0060443	mammary gland morphogenesis	3/232	46/18986	0.0652173913043478	5.33714392803598	3.27563196353	0.0185880475849786	0.0434805752042497	0.0217178098295068	DDR1/ESR1/AR	3
BP	GO:0071901	negative regulation of protein serine/threonine kinase activity	4/232	83/18986	0.0481927710843374	3.94391358537599	2.9895173214316	0.0188383435508676	0.0440419666612958	0.0219982153403991	PRKCD/PRKCH/CDKN1B/CDKN2A	4
BP	GO:0090287	regulation of cellular response to growth factor stimulus	10/232	381/18986	0.026246719160105	2.14793193954204	2.51748057193688	0.0191283729967622	0.044695586302817	0.0223246872651311	VEGFA/KDR/ITGB1/HSPA1A/XIAP/HSPA5/HTRA1/TP53/IL12B/NRP1	10
BP	GO:0019362	pyridine nucleotide metabolic process	6/232	172/18986	0.0348837209302326	2.85475140336808	2.71776373537191	0.019246955357129	0.044899062251546	0.0224263200503143	TP53/ALDOA/COL6A1/HTR2A/INS/LIPA	6
BP	GO:0030856	regulation of epithelial cell differentiation	6/232	172/18986	0.0348837209302326	2.85475140336808	2.71776373537191	0.019246955357129	0.044899062251546	0.0224263200503143	VEGFA/MMP9/PRKCH/IKBKB/CDKN1B/TNF	6
BP	GO:0046496	nicotinamide nucleotide metabolic process	6/232	172/18986	0.0348837209302326	2.85475140336808	2.71776373537191	0.019246955357129	0.044899062251546	0.0224263200503143	TP53/ALDOA/COL6A1/HTR2A/INS/LIPA	6
BP	GO:0006090	pyruvate metabolic process	5/232	126/18986	0.0396825396825397	3.24746852764094	2.81520732945131	0.0193487708669456	0.0450873810501687	0.0225203820961037	ALDOA/COL6A1/HTR2A/INS/LIPA	5
BP	GO:0009185	ribonucleoside diphosphate metabolic process	5/232	126/18986	0.0396825396825397	3.24746852764094	2.81520732945131	0.0193487708669456	0.0450873810501687	0.0225203820961037	ALDOA/COL6A1/HTR2A/INS/LIPA	5
BP	GO:0110053	regulation of actin filament organization	8/232	273/18986	0.0293040293040293	2.39813060502716	2.58797272289663	0.0193596625834187	0.0450881901997268	0.0225207862525838	RHOA/APOA1/PRKCD/FLNA/BRAF/TGFBR1/NRP1/ALOX15	8
BP	GO:0070227	lymphocyte apoptotic process	4/232	84/18986	0.0476190476190476	3.89696223316913	2.9595857966836	0.0195961639907881	0.0455893347250326	0.0227710994429351	PRKCQ/TP53/LIPA/BCL2	4
BP	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	4/232	84/18986	0.0476190476190476	3.89696223316913	2.9595857966836	0.0195961639907881	0.0455893347250326	0.0227710994429351	PRKCQ/BRD4/IL12B/PRKCZ	4
BP	GO:0032309	icosanoid secretion	3/232	47/18986	0.0638297872340425	5.22358767424798	3.22443968850479	0.0196803690826565	0.0456610190979052	0.0228069045713283	PLA2G2A/PLA2G10/PTGS2	3
BP	GO:0033173	calcineurin-NFAT signaling cascade	3/232	47/18986	0.0638297872340425	5.22358767424798	3.22443968850479	0.0196803690826565	0.0456610190979052	0.0228069045713283	CLEC7A/TNF/PPP3CA	3
BP	GO:0042789	mRNA transcription by RNA polymerase II	3/232	47/18986	0.0638297872340425	5.22358767424798	3.22443968850479	0.0196803690826565	0.0456610190979052	0.0228069045713283	THRA/FLNA/THRB	3
BP	GO:0050798	activated T cell proliferation	3/232	47/18986	0.0638297872340425	5.22358767424798	3.22443968850479	0.0196803690826565	0.0456610190979052	0.0228069045713283	IGF2/IL12B/PPP3CA	3
BP	GO:0071763	nuclear membrane organization	3/232	47/18986	0.0638297872340425	5.22358767424798	3.22443968850479	0.0196803690826565	0.0456610190979052	0.0228069045713283	PRKCA/ATR/CDK1	3
BP	GO:0009141	nucleoside triphosphate metabolic process	8/232	274/18986	0.0291970802919708	2.38937830354896	2.57654675078153	0.0197396402569842	0.0457297894925857	0.0228412542170392	HSPA1A/ALDOA/MYH7/COL6A1/HTR2A/HSPA8/INS/LIPA	8
BP	GO:0007009	plasma membrane organization	6/232	173/18986	0.0346820809248555	2.83824995016942	2.70147482079804	0.0197420934058263	0.0457297894925857	0.0228412542170392	MYH9/PRKCD/COL5A1/COL6A1/AR/PLEC	6
BP	GO:0050792	regulation of viral process	6/232	173/18986	0.0346820809248555	2.83824995016942	2.70147482079804	0.0197420934058263	0.0457297894925857	0.0228412542170392	DDB1/CXCL8/LTF/PPIA/TNF/BCL2	6
BP	GO:0002424	T cell mediated immune response to tumor cell	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	HLA-A/AHR	2
BP	GO:0002428	antigen processing and presentation of peptide antigen via MHC class Ib	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	MICA/HLA-A	2
BP	GO:0010612	regulation of cardiac muscle adaptation	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	LMNA/PPP3CA	2
BP	GO:0030889	negative regulation of B cell proliferation	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	ATM/CDKN2A	2
BP	GO:0032780	negative regulation of ATP-dependent activity	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	TP53/LTF	2
BP	GO:0034112	positive regulation of homotypic cell-cell adhesion	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	PLAUR/HTR2A	2
BP	GO:0035234	ectopic germ cell programmed cell death	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	DDB1/BCL2L1	2
BP	GO:0035728	response to hepatocyte growth factor	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	NRP1/HGF	2
BP	GO:0042159	lipoprotein catabolic process	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	ATM/LIPA	2
BP	GO:0071071	regulation of phospholipid biosynthetic process	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	HTR2A/PDGFA	2
BP	GO:0090494	dopamine uptake	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	SNCA/SLC6A3	2
BP	GO:0150078	positive regulation of neuroinflammatory response	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	MMP8/TNF	2
BP	GO:1902916	positive regulation of protein polyubiquitination	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	SKP2/XIAP	2
BP	GO:1903242	regulation of cardiac muscle hypertrophy in response to stress	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	LMNA/PPP3CA	2
BP	GO:1903729	regulation of plasma membrane organization	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	MYH9/PRKCD	2
BP	GO:2001224	positive regulation of neuron migration	2/232	18/18986	0.111111111111111	9.09291187739464	3.82060932080302	0.0199992476732625	0.0459273808006824	0.0229399477240374	PLAA/FLNA	2
BP	GO:0051259	protein complex oligomerization	8/232	275/18986	0.0290909090909091	2.38068965517241	2.56517061216095	0.0201249119528322	0.046191155936828	0.0230716989305854	SNCA/KCNA2/TP53/ALDOA/COL1A2/COL6A1/TRPA1/MAPT	8
BP	GO:0055074	calcium ion homeostasis	9/232	329/18986	0.027355623100304	2.23868043182056	2.52080155108328	0.0202103508768451	0.046362371432076	0.0231572181664325	KDR/SNCA/PDE4D/EDNRA/FLNA/F2/HTR2A/TRPA1/BCL2	9
BP	GO:0002437	inflammatory response to antigenic stimulus	4/232	85/18986	0.0470588235294118	3.85111561866126	2.93011211675564	0.0203725723055306	0.0466594103794584	0.0233055840824974	FCGR2A/IL12B/FCGR3A/TNF	4
BP	GO:0014855	striated muscle cell proliferation	4/232	85/18986	0.0470588235294118	3.85111561866126	2.93011211675564	0.0203725723055306	0.0466594103794584	0.0233055840824974	CDK1/EPHB1/TGFBR1/HGF	4
BP	GO:0097061	dendritic spine organization	4/232	85/18986	0.0470588235294118	3.85111561866126	2.93011211675564	0.0203725723055306	0.0466594103794584	0.0233055840824974	EPHB2/EPHB3/EPHB1/INS	4
BP	GO:0046486	glycerolipid metabolic process	10/232	385/18986	0.025974025974026	2.1256157635468	2.48173109478675	0.020396067565449	0.0466882146198393	0.0233199713120117	APOA1/PLA2G2A/ATM/PLA2G5/PLA2G10/HTR2A/PON1/PDGFA/LIPA/ALOX15	10
BP	GO:0051651	maintenance of location in cell	7/232	224/18986	0.03125	2.55738146551724	2.60784504473599	0.0204787281443003	0.0468523496763126	0.023401953988784	HEXA/SNCA/PDE4D/HSPA5/FLNA/F2/HTR2A	7
BP	GO:0003231	cardiac ventricle development	5/232	128/18986	0.0390625	3.19672683189655	2.77354720096772	0.0205590963883145	0.0469859412915194	0.0234686807346987	EDNRA/MYH7/MDM2/COL11A1/TGFBR1	5
BP	GO:0071774	response to fibroblast growth factor	5/232	128/18986	0.0390625	3.19672683189655	2.77354720096772	0.0205590963883145	0.0469859412915194	0.0234686807346987	ITGB1/CXCL8/NR4A1/COL1A1/NPR2	5
BP	GO:0002673	regulation of acute inflammatory response	3/232	48/18986	0.0625	5.11476293103448	3.17468557486073	0.0208074434388211	0.0473258660342548	0.0236384673781456	INS/TNF/PTGS2	3
BP	GO:0007520	myoblast fusion	3/232	48/18986	0.0625	5.11476293103448	3.17468557486073	0.0208074434388211	0.0473258660342548	0.0236384673781456	MYH9/ITGB1/ADAMTS5	3
BP	GO:0007622	rhythmic behavior	3/232	48/18986	0.0625	5.11476293103448	3.17468557486073	0.0208074434388211	0.0473258660342548	0.0236384673781456	KCNA2/EGR1/TP53	3
BP	GO:0032210	regulation of telomere maintenance via telomerase	3/232	48/18986	0.0625	5.11476293103448	3.17468557486073	0.0208074434388211	0.0473258660342548	0.0236384673781456	ATM/ATR/TP53	3
BP	GO:0032881	regulation of polysaccharide metabolic process	3/232	48/18986	0.0625	5.11476293103448	3.17468557486073	0.0208074434388211	0.0473258660342548	0.0236384673781456	IGF2/AP2A1/INS	3
BP	GO:0045622	regulation of T-helper cell differentiation	3/232	48/18986	0.0625	5.11476293103448	3.17468557486073	0.0208074434388211	0.0473258660342548	0.0236384673781456	BRD4/IL12B/PRKCZ	3
BP	GO:0046189	phenol-containing compound biosynthetic process	3/232	48/18986	0.0625	5.11476293103448	3.17468557486073	0.0208074434388211	0.0473258660342548	0.0236384673781456	NR4A2/SNCA/SLC6A3	3
BP	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	3/232	48/18986	0.0625	5.11476293103448	3.17468557486073	0.0208074434388211	0.0473258660342548	0.0236384673781456	HSPA1A/TP53/BCL2L1	3
BP	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	3/232	48/18986	0.0625	5.11476293103448	3.17468557486073	0.0208074434388211	0.0473258660342548	0.0236384673781456	MMP2/PPIA/INS	3
BP	GO:0034976	response to endoplasmic reticulum stress	8/232	277/18986	0.0288808664259928	2.36350056018922	2.5425661166313	0.0209114822303758	0.0475372131935604	0.0237440316995062	CXCL8/HSPA1A/HSPA5/TP53/ALOX5/BCL2L1/BCL2/ALOX15	8
BP	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	4/232	86/18986	0.0465116279069767	3.80633520449078	2.90108334138475	0.0211676774549554	0.0479999681762537	0.0239751699644574	PSAP/EDNRA/FLNA/HTR1A	4
BP	GO:0050871	positive regulation of B cell activation	4/232	86/18986	0.0465116279069767	3.80633520449078	2.90108334138475	0.0211676774549554	0.0479999681762537	0.0239751699644574	MMP14/EPHB2/TNFSF13/BCL2	4
BP	GO:0007613	memory	5/232	129/18986	0.0387596899224806	3.17194600374232	2.75302348440265	0.021182399426705	0.0479999681762537	0.0239751699644574	HTR2A/PRKCZ/MAPT/PTGS2/SLC6A4	5
BP	GO:0042471	ear morphogenesis	5/232	129/18986	0.0387596899224806	3.17194600374232	2.75302348440265	0.021182399426705	0.0479999681762537	0.0239751699644574	KCNQ4/EDNRA/EPHB2/COL2A1/COL11A1	5
BP	GO:0045471	response to ethanol	5/232	129/18986	0.0387596899224806	3.17194600374232	2.75302348440265	0.021182399426705	0.0479999681762537	0.0239751699644574	MAOB/CDK1/HSPA8/TNF/SLC6A3	5
BP	GO:0051209	release of sequestered calcium ion into cytosol	5/232	129/18986	0.0387596899224806	3.17194600374232	2.75302348440265	0.021182399426705	0.0479999681762537	0.0239751699644574	SNCA/PDE4D/FLNA/F2/HTR2A	5
BP	GO:0001818	negative regulation of cytokine production	10/232	388/18986	0.0257731958762887	2.10918059011731	2.45520262401896	0.0213864309210255	0.0484366412173225	0.0241932807419495	APOA1/INHBA/PLA2G10/EPHB2/LTF/F2/IL12B/TNF/HAVCR2/HGF	10
BP	GO:0001508	action potential	6/232	177/18986	0.0338983050847458	2.77410870835769	2.63746281284131	0.0218093703393592	0.0493093872755462	0.024629202595166	NTRK2/KCNA2/KCNQ2/FLNA/TNF/NPR2	6
BP	GO:0032612	interleukin-1 production	5/232	130/18986	0.0384615384615385	3.14754641909814	2.73269894166502	0.021817904753352	0.0493093872755462	0.024629202595166	APOA1/EGR1/CLEC7A/TNF/HAVCR2	5
BP	GO:0032652	regulation of interleukin-1 production	5/232	130/18986	0.0384615384615385	3.14754641909814	2.73269894166502	0.021817904753352	0.0493093872755462	0.024629202595166	APOA1/EGR1/CLEC7A/TNF/HAVCR2	5
BP	GO:0051283	negative regulation of sequestering of calcium ion	5/232	130/18986	0.0384615384615385	3.14754641909814	2.73269894166502	0.021817904753352	0.0493093872755462	0.024629202595166	SNCA/PDE4D/FLNA/F2/HTR2A	5
BP	GO:0007163	establishment or maintenance of cell polarity	7/232	227/18986	0.0308370044052863	2.52358347258089	2.56848289083483	0.0218370069089315	0.0493264878724728	0.0246377440532833	RHOA/MYH9/ITGB1/LMNA/EPHB1/LAMA1/PRKCZ	7
BP	GO:0006458	'de novo' protein folding	3/232	49/18986	0.0612244897959184	5.0103800140746	3.12629758445391	0.0219692997918349	0.0493645433052475	0.0246567520964864	HSPA1A/HSPA5/HSPA8	3
BP	GO:0021795	cerebral cortex cell migration	3/232	49/18986	0.0612244897959184	5.0103800140746	3.12629758445391	0.0219692997918349	0.0493645433052475	0.0246567520964864	RHOA/COL3A1/LAMB1	3
BP	GO:0030521	androgen receptor signaling pathway	3/232	49/18986	0.0612244897959184	5.0103800140746	3.12629758445391	0.0219692997918349	0.0493645433052475	0.0246567520964864	RHOA/SMARCA4/AR	3
BP	GO:0032506	cytokinetic process	3/232	49/18986	0.0612244897959184	5.0103800140746	3.12629758445391	0.0219692997918349	0.0493645433052475	0.0246567520964864	RHOA/MYH9/PLEC	3
BP	GO:0033628	regulation of cell adhesion mediated by integrin	3/232	49/18986	0.0612244897959184	5.0103800140746	3.12629758445391	0.0219692997918349	0.0493645433052475	0.0246567520964864	PDE3B/PLAU/CYP1B1	3
BP	GO:0035850	epithelial cell differentiation involved in kidney development	3/232	49/18986	0.0612244897959184	5.0103800140746	3.12629758445391	0.0219692997918349	0.0493645433052475	0.0246567520964864	MMP9/EDNRA/LAMB2	3
BP	GO:0042149	cellular response to glucose starvation	3/232	49/18986	0.0612244897959184	5.0103800140746	3.12629758445391	0.0219692997918349	0.0493645433052475	0.0246567520964864	HSPA5/TP53/BCL2	3
BP	GO:0042551	neuron maturation	3/232	49/18986	0.0612244897959184	5.0103800140746	3.12629758445391	0.0219692997918349	0.0493645433052475	0.0246567520964864	NR4A2/EDNRA/BCL2	3
BP	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	3/232	49/18986	0.0612244897959184	5.0103800140746	3.12629758445391	0.0219692997918349	0.0493645433052475	0.0246567520964864	RHOA/LAMA1/PRKCZ	3
BP	GO:0097720	calcineurin-mediated signaling	3/232	49/18986	0.0612244897959184	5.0103800140746	3.12629758445391	0.0219692997918349	0.0493645433052475	0.0246567520964864	CLEC7A/TNF/PPP3CA	3
BP	GO:0002524	hypersensitivity	2/232	19/18986	0.105263157894737	8.61433756805808	3.69327751741879	0.0221744285822429	0.0494615840467765	0.0247052223009477	FCGR2A/FCGR3A	2
BP	GO:0002693	positive regulation of cellular extravasation	2/232	19/18986	0.105263157894737	8.61433756805808	3.69327751741879	0.0221744285822429	0.0494615840467765	0.0247052223009477	ICAM1/IL1R1	2
BP	GO:0014819	regulation of skeletal muscle contraction	2/232	19/18986	0.105263157894737	8.61433756805808	3.69327751741879	0.0221744285822429	0.0494615840467765	0.0247052223009477	MYH7/NR4A1	2
BP	GO:0032026	response to magnesium ion	2/232	19/18986	0.105263157894737	8.61433756805808	3.69327751741879	0.0221744285822429	0.0494615840467765	0.0247052223009477	SNCA/MDM2	2
BP	GO:0032310	prostaglandin secretion	2/232	19/18986	0.105263157894737	8.61433756805808	3.69327751741879	0.0221744285822429	0.0494615840467765	0.0247052223009477	PLA2G10/PTGS2	2
BP	GO:0045945	positive regulation of transcription by RNA polymerase III	2/232	19/18986	0.105263157894737	8.61433756805808	3.69327751741879	0.0221744285822429	0.0494615840467765	0.0247052223009477	INHBA/AR	2
BP	GO:0048486	parasympathetic nervous system development	2/232	19/18986	0.105263157894737	8.61433756805808	3.69327751741879	0.0221744285822429	0.0494615840467765	0.0247052223009477	NRP2/NRP1	2
BP	GO:0055003	cardiac myofibril assembly	2/232	19/18986	0.105263157894737	8.61433756805808	3.69327751741879	0.0221744285822429	0.0494615840467765	0.0247052223009477	PDGFRB/PDGFRA	2
BP	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	2/232	19/18986	0.105263157894737	8.61433756805808	3.69327751741879	0.0221744285822429	0.0494615840467765	0.0247052223009477	HSPA1A/XIAP	2
BP	GO:0090493	catecholamine uptake	2/232	19/18986	0.105263157894737	8.61433756805808	3.69327751741879	0.0221744285822429	0.0494615840467765	0.0247052223009477	SNCA/SLC6A3	2
BP	GO:0098543	detection of other organism	2/232	19/18986	0.105263157894737	8.61433756805808	3.69327751741879	0.0221744285822429	0.0494615840467765	0.0247052223009477	HLA-A/CLEC7A	2
BP	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	2/232	19/18986	0.105263157894737	8.61433756805808	3.69327751741879	0.0221744285822429	0.0494615840467765	0.0247052223009477	PDE4D/PDE4B	2
BP	GO:1902570	protein localization to nucleolus	2/232	19/18986	0.105263157894737	8.61433756805808	3.69327751741879	0.0221744285822429	0.0494615840467765	0.0247052223009477	CDKN2A/POLR1A	2
BP	GO:1903427	negative regulation of reactive oxygen species biosynthetic process	2/232	19/18986	0.105263157894737	8.61433756805808	3.69327751741879	0.0221744285822429	0.0494615840467765	0.0247052223009477	RHOA/INS	2
BP	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	6/232	178/18986	0.0337078651685393	2.75852382797365	2.62173799369706	0.0223481728118151	0.0497971792304958	0.0248728464031008	IKBKB/HSPA1A/XIAP/HSPA8/TNF/HAVCR2	6
BP	GO:0072524	pyridine-containing compound metabolic process	6/232	178/18986	0.0337078651685393	2.75852382797365	2.62173799369706	0.0223481728118151	0.0497971792304958	0.0248728464031008	TP53/ALDOA/COL6A1/HTR2A/INS/LIPA	6
CC	GO:0062023	collagen-containing extracellular matrix	44/233	430/19960	0.102325581395349	8.76574508433975	17.69224985195	9.44011370602272e-29	3.48340195752238e-26	2.48424044895335e-26	MMP2/APOA1/PSAP/ICAM1/MMP9/MMP8/ADAMTS4/ADAMTS1/HTRA1/AHSG/LAMA1/F2/FGA/FGB/FGG/COL1A2/COL1A1/COL2A1/COL3A1/COL4A1/COL5A1/COL6A1/COL11A1/COL18A1/COL27A1/COL4A2/COL5A2/COL6A2/COL11A2/COL4A3/COL6A3/COL4A4/COL4A5/COL4A6/LAMA3/LAMA4/LAMA5/LAMB1/LAMB2/LAMB3/ADAMTS5/F13A1/PF4/PLG	44
CC	GO:0005788	endoplasmic reticulum lumen	36/233	314/19960	0.114649681528662	9.82149203138241	17.1232669618703	2.70825657523462e-25	4.05406334664569e-23	2.89121619358557e-23	APOA1/HSPA5/PLAUR/ERAP1/AHSG/F2/ERAP2/FGA/FGG/IL12B/COL1A2/COL1A1/COL2A1/COL3A1/COL4A1/COL5A1/COL6A1/COL11A1/COL18A1/COL27A1/COL4A2/COL5A2/COL6A2/COL11A2/COL4A3/COL6A3/COL4A4/COL4A5/COL4A6/LAMB1/LAMB2/ADAMTS5/PDGFA/ARSA/INS/PTGS2	36
CC	GO:0098644	complex of collagen trimers	15/233	21/19960	0.714285714285714	61.1894543225015	29.9912932991195	3.29598646068755e-25	4.05406334664569e-23	2.89121619358557e-23	COL1A2/COL1A1/COL2A1/COL3A1/COL4A1/COL5A1/COL11A1/COL27A1/COL4A2/COL5A2/COL11A2/COL4A3/COL4A4/COL4A5/COL4A6	15
CC	GO:0005581	collagen trimer	19/233	86/19960	0.22093023255814	18.9260405230063	18.10538582408	2.46482580479544e-19	2.27380180492379e-17	1.62159592420753e-17	COL1A2/COL1A1/COL2A1/COL3A1/COL4A1/COL5A1/COL6A1/COL11A1/COL18A1/COL27A1/COL4A2/COL5A2/COL6A2/COL11A2/COL4A3/COL6A3/COL4A4/COL4A5/COL4A6	19
CC	GO:0005604	basement membrane	18/233	92/19960	0.195652173913043	16.7605896622504	16.4666830896763	2.28539556525468e-17	1.68662192715795e-15	1.20283977118667e-15	ADAMTS1/LAMA1/COL2A1/COL4A1/COL5A1/COL6A1/COL18A1/COL4A2/COL4A3/COL4A4/COL4A5/COL4A6/LAMA3/LAMA4/LAMA5/LAMB1/LAMB2/LAMB3	18
CC	GO:0005583	fibrillar collagen trimer	9/233	12/19960	0.75	64.2489270386266	23.8183094330489	7.35869157407814e-16	3.87908170119262e-14	2.76642540378877e-14	COL1A2/COL1A1/COL2A1/COL3A1/COL5A1/COL11A1/COL27A1/COL5A2/COL11A2	9
CC	GO:0098643	banded collagen fibril	9/233	12/19960	0.75	64.2489270386266	23.8183094330489	7.35869157407814e-16	3.87908170119262e-14	2.76642540378877e-14	COL1A2/COL1A1/COL2A1/COL3A1/COL5A1/COL11A1/COL27A1/COL5A2/COL11A2	9
CC	GO:0034774	secretory granule lumen	26/233	324/19960	0.0802469135802469	6.87437079425635	11.5857506336536	1.09351185286485e-14	5.04382342133913e-13	3.59707846337122e-13	VEGFA/APOA1/CTSA/PRKCD/EEF1A1/MMP8/ALDOA/GLA/AHSG/IGF2/LTF/FGA/FGB/FGG/PPIA/HSPA8/F13A1/PDGFA/PF4/MAN2B1/ARSA/GRN/INS/PLG/HGF/ALOX5	26
CC	GO:0060205	cytoplasmic vesicle lumen	26/233	329/19960	0.0790273556231003	6.76989707397889	11.4686323515137	1.57287119445054e-14	6.23665060894431e-13	4.44776109609493e-13	VEGFA/APOA1/CTSA/PRKCD/EEF1A1/MMP8/ALDOA/GLA/AHSG/IGF2/LTF/FGA/FGB/FGG/PPIA/HSPA8/F13A1/PDGFA/PF4/MAN2B1/ARSA/GRN/INS/PLG/HGF/ALOX5	26
CC	GO:0031983	vesicle lumen	26/233	330/19960	0.0787878787878788	6.74938223436078	11.445501592023	1.69014921651607e-14	6.23665060894431e-13	4.44776109609493e-13	VEGFA/APOA1/CTSA/PRKCD/EEF1A1/MMP8/ALDOA/GLA/AHSG/IGF2/LTF/FGA/FGB/FGG/PPIA/HSPA8/F13A1/PDGFA/PF4/MAN2B1/ARSA/GRN/INS/PLG/HGF/ALOX5	26
CC	GO:0009897	external side of plasma membrane	27/233	407/19960	0.0663390663390663	5.68295177737238	10.3735407533294	3.2865998049696e-13	1.10250484366708e-11	7.86267895925743e-12	KDR/ITGA1/PDGFRA/ITGB1/ITGAL/ICAM1/ITGB2/IL1R1/PLAU/FCGR2A/PLAUR/ABCA1/F2/ANPEP/FGA/FGB/FGG/IL12B/CXCR1/B4GALT1/KLRK1/MICA/HLA-A/FCGR3A/TNF/CXCR2/PLG	27
CC	GO:0031093	platelet alpha granule lumen	12/233	67/19960	0.17910447761194	15.3430273525078	12.7804137551354	1.64133273703854e-11	5.04709816639351e-10	3.59941389701434e-10	VEGFA/ALDOA/AHSG/IGF2/FGA/FGB/FGG/F13A1/PDGFA/PF4/PLG/HGF	12
CC	GO:0031091	platelet alpha granule	13/233	91/19960	0.142857142857143	12.2378908645003	11.677081967632	4.58416187263313e-11	1.3011967161551e-09	9.27967990411564e-10	VEGFA/SNCA/ALDOA/AHSG/IGF2/FGA/FGB/FGG/F13A1/PDGFA/PF4/PLG/HGF	13
CC	GO:0098636	protein complex involved in cell adhesion	10/233	58/19960	0.172413793103448	14.7698682847418	11.4133267080405	1.23790032678612e-09	3.26275157560057e-08	2.32688031350775e-08	ITGA1/ITGB1/ITGAL/ITGB2/PLAU/ITGB7/PLAUR/LAMA1/LAMB1/LAMB2	10
CC	GO:0030055	cell-substrate junction	22/233	434/19960	0.0506912442396313	4.34247740353237	7.65109385650493	8.86163981857168e-09	2.17996339536863e-07	1.554673652381e-07	ITGA1/RHOA/PDGFRB/MYH9/ITGB1/SHC1/ICAM1/ITGB2/PLAU/ITGB7/HSPA1A/HSPA5/PLAUR/MMP14/FLNA/LAMA3/PPIA/HSPA8/NRP1/FLT1/SLC6A4/PLEC	22
CC	GO:0005925	focal adhesion	21/233	424/19960	0.0495283018867925	4.24285367236214	7.33515481925252	2.92386045809823e-08	6.74315318148905e-07	4.80898101660894e-07	ITGA1/RHOA/PDGFRB/MYH9/ITGB1/SHC1/ICAM1/ITGB2/PLAU/ITGB7/HSPA1A/HSPA5/PLAUR/MMP14/FLNA/PPIA/HSPA8/NRP1/FLT1/SLC6A4/PLEC	21
CC	GO:0043202	lysosomal lumen	10/233	98/19960	0.102040816326531	8.74135061750022	8.34901255499594	2.2110282764149e-07	4.7992319646888e-06	3.42264439073513e-06	HEXA/PDGFRB/PSAP/CTSA/GLA/HSPA8/MAN2B1/ARSA/MANBA/LIPA	10
CC	GO:0072562	blood microparticle	11/233	144/19960	0.0763888888888889	6.54387219837864	7.25610045557376	1.0375145428205e-06	2.12690481278203e-05	1.51683412693056e-05	APOA1/HSPA1A/AHSG/F2/FGA/FGB/FGG/HSPA8/F13A1/PON1/PLG	11
CC	GO:0098637	protein complex involved in cell-matrix adhesion	5/233	17/19960	0.294117647058824	25.1956576622065	10.8463465033987	1.14601385026968e-06	2.22567953026059e-05	1.58727680092754e-05	PLAU/PLAUR/LAMA1/LAMB1/LAMB2	5
CC	GO:0005775	vacuolar lumen	12/233	178/19960	0.0674157303370786	5.77518445291026	6.95475573985562	1.26753571951114e-06	2.33860340249805e-05	1.6678101572515e-05	HEXA/PDGFRB/PSAP/CTSA/PRKCD/GLA/HSPA8/MAN2B1/ARSA/GRN/MANBA/LIPA	12
CC	GO:0045121	membrane raft	15/233	293/19960	0.0511945392491468	4.38559228932605	6.34477514411208	1.97147709584992e-06	3.46416689699344e-05	2.47052267650366e-05	KDR/ITGB1/ICAM1/ITGB2/IKBKB/EPHB1/ABCA1/HTR2A/TGFBR1/OLR1/TNF/MAPT/PTGS2/SLC6A4/SLC6A3	15
CC	GO:0098857	membrane microdomain	15/233	295/19960	0.0508474576271186	4.35585946024587	6.31080301983372	2.14415724735797e-06	3.59633647397769e-05	2.56478139636121e-05	KDR/ITGB1/ICAM1/ITGB2/IKBKB/EPHB1/ABCA1/HTR2A/TGFBR1/OLR1/TNF/MAPT/PTGS2/SLC6A4/SLC6A3	15
CC	GO:0005766	primary lysosome	10/233	155/19960	0.0645161290322581	5.52678942267756	6.1487317347145	1.45108414666702e-05	0.000223104187550054	0.000159110103801208	HEXA/PSAP/CTSA/PRKCD/GLA/B4GALT1/MAN2B1/ARSA/GRN/MANBA	10
CC	GO:0042582	azurophil granule	10/233	155/19960	0.0645161290322581	5.52678942267756	6.1487317347145	1.45108414666702e-05	0.000223104187550054	0.000159110103801208	HEXA/PSAP/CTSA/PRKCD/GLA/B4GALT1/MAN2B1/ARSA/GRN/MANBA	10
CC	GO:0030667	secretory granule membrane	14/233	320/19960	0.04375	3.74785407725322	5.38536000716784	2.56194985457905e-05	0.000378143798535868	0.000269678932060953	SNCA/RHOA/PSAP/ITGAL/ITGB2/PLAU/FCGR2A/PLAUR/ANPEP/CXCR1/B4GALT1/OLR1/MANBA/CXCR2	14
CC	GO:0008305	integrin complex	5/233	31/19960	0.161290322580645	13.8169735566939	7.76140612374924	2.75390380053506e-05	0.000390842500922091	0.000278735202483306	ITGA1/ITGB1/ITGAL/ITGB2/ITGB7	5
CC	GO:0101002	ficolin-1-rich granule	10/233	185/19960	0.0540540540540541	4.6305533000812	5.39159500674087	6.59743810172434e-05	0.000901649873902327	0.000643025156113484	RHOA/ITGB2/MMP9/EEF1A1/HSPA1A/ALDOA/LTA4H/PPIA/HSPA8/ALOX5	10
CC	GO:1904813	ficolin-1-rich granule lumen	8/233	124/19960	0.0645161290322581	5.52678942267756	5.495293750027	0.000105264659994264	0.0013872378406387	0.00098932951122429	MMP9/EEF1A1/HSPA1A/ALDOA/LTA4H/PPIA/HSPA8/ALOX5	8
CC	GO:0070820	tertiary granule	9/233	164/19960	0.0548780487804878	4.70114100282634	5.17232325925285	0.000136242761871168	0.00173357169415383	0.00123632270300516	RHOA/ITGB2/MMP9/PLAU/MMP8/ALDOA/LTF/LTA4H/OLR1	9
CC	GO:0001772	immunological synapse	5/233	48/19960	0.104166666666667	8.92346208869814	5.97303402241931	0.000236188188733717	0.00278802144591652	0.00198831938804487	MYH9/ICAM1/PRKCQ/GZMA/HAVCR2	5
CC	GO:0043209	myelin sheath	5/233	48/19960	0.104166666666667	8.92346208869814	5.97303402241931	0.000236188188733717	0.00278802144591652	0.00198831938804487	ITGB1/PRKCZ/CA2/BCL2/PLEC	5
CC	GO:0005883	neurofilament	3/233	11/19960	0.272727272727273	23.3632461958642	8.0628290089127	0.000241779637586257	0.00278802144591652	0.00198831938804487	HTR2A/NRP1/DYRK1A	3
CC	GO:1904724	tertiary granule lumen	5/233	55/19960	0.0909090909090909	7.78774873195474	5.47826250029631	0.000449104370090438	0.00502180341101126	0.0035813745621247	MMP9/MMP8/ALDOA/LTF/LTA4H	5
CC	GO:0098802	plasma membrane signaling receptor complex	12/233	326/19960	0.0368098159509202	3.15332157244793	4.26020134638098	0.000474138079057174	0.00514579268153227	0.00366979937350754	ITGA1/HTR3A/ITGB1/ITGAL/ITGB2/IKBKB/CHUK/ITGB7/HTR3B/FLNA/IL18R1/TGFBR1	12
CC	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	3/233	14/19960	0.214285714285714	18.3568362967505	7.06030569114169	0.00051973561296408	0.00547949831953559	0.0039077865636397	CRBN/DDB1/CDKN1B	3
CC	GO:0035578	azurophil granule lumen	6/233	91/19960	0.0659340659340659	5.64825732207706	4.82991714468417	0.000691960435424592	0.00709259446310207	0.00505819031743123	CTSA/PRKCD/GLA/MAN2B1/ARSA/GRN	6
CC	GO:0098685	Schaffer collateral - CA1 synapse	6/233	99/19960	0.0606060606060606	5.19183248796983	4.54399440704114	0.00107687451218392	0.0107396404052937	0.00765913593302932	ITGB1/PLAT/PPP3CA/PLG/PRKCZ/ADORA3	6
CC	GO:1902554	serine/threonine protein kinase complex	7/233	139/19960	0.0503597122302158	4.31407663568716	4.26112224507822	0.00125074923400111	0.0121101898642304	0.00863656387407671	CDK2/CCNA2/IKBKB/CHUK/CDK1/TGFBR1/PRKCZ	7
CC	GO:0043197	dendritic spine	8/233	180/19960	0.0444444444444444	3.80734382451121	4.11183369946946	0.00127993876613817	0.0121101898642304	0.00863656387407671	NTRK2/PDE4B/RHOA/ITGB1/EPHB2/HSPA8/PPP3CA/MAPT	8
CC	GO:0044309	neuron spine	8/233	182/19960	0.043956043956044	3.76550488138471	4.07320027484019	0.00137325268795554	0.0126682560463898	0.00903455715760221	NTRK2/PDE4B/RHOA/ITGB1/EPHB2/HSPA8/PPP3CA/MAPT	8
CC	GO:1902911	protein kinase complex	7/233	153/19960	0.0457516339869281	3.91932452523212	3.93944977317082	0.00216618249582624	0.01928025645753	0.0137500046052846	CDK2/CCNA2/IKBKB/CHUK/CDK1/TGFBR1/PRKCZ	7
CC	GO:0031594	neuromuscular junction	5/233	78/19960	0.0641025641025641	5.4913612853527	4.31928722733929	0.00219450073500341	0.01928025645753	0.0137500046052846	MYH9/ITGB1/COL4A5/LAMA5/LAMB2	5
CC	GO:0030016	myofibril	9/233	243/19960	0.037037037037037	3.17278652042601	3.70353628712437	0.00229037553960862	0.0195464447261197	0.0139398407688772	MMP2/TPM3/PDE4B/ALDOA/FLNA/MYH7/COL6A1/PPP3CA/PLEC	9
CC	GO:0034399	nuclear periphery	7/233	155/19960	0.0451612903225806	3.86875259587429	3.89662263434013	0.00233074137655628	0.0195464447261197	0.0139398407688772	PRKCD/SMARCA4/TP53/LMNA/PRKCZ/ALOX5/MAPT	7
CC	GO:0043679	axon terminus	6/233	117/19960	0.0512820512820513	4.39308902828216	4.00038091661638	0.0025280634586156	0.0207301203606479	0.0147839968340094	NTRK2/SNCA/KCNA2/PDYN/HSPA8/SLC6A3	6
CC	GO:0042581	specific granule	7/233	160/19960	0.04375	3.74785407725322	3.79260741333146	0.0027843890952515	0.0223356429597349	0.0159289994007523	ITGAL/ITGB2/PLAU/MMP8/PLAUR/LTF/OLR1	7
CC	GO:0031968	organelle outer membrane	9/233	252/19960	0.0357142857142857	3.05947271612508	3.57562416505706	0.00292072968989972	0.0227846664254021	0.0162492272324933	MAOA/MAOB/PLA2G2A/BPHL/RAF1/BCL2L1/BCL2/PTGS2/PLEC	9
CC	GO:0043292	contractile muscle fiber	9/233	253/19960	0.0355731225296443	3.04737993859099	3.56176509137754	0.00299847600057373	0.0227846664254021	0.0162492272324933	MMP2/TPM3/PDE4B/ALDOA/FLNA/MYH7/COL6A1/PPP3CA/PLEC	9
CC	GO:0019867	outer membrane	9/233	254/19960	0.0354330708661417	3.03538237977763	3.54797423129079	0.00307784840566092	0.0227846664254021	0.0162492272324933	MAOA/MAOB/PLA2G2A/BPHL/RAF1/BCL2L1/BCL2/PTGS2/PLEC	9
CC	GO:0009898	cytoplasmic side of plasma membrane	7/233	163/19960	0.0429447852760736	3.67887516785592	3.7321871605379	0.00308735317417372	0.0227846664254021	0.0162492272324933	RHOA/MYH9/IKBKB/CHUK/AP2A1/PPP3CA/ALOX15	7
CC	GO:0098562	cytoplasmic side of membrane	8/233	210/19960	0.0380952380952381	3.26343756386675	3.58353329439007	0.00334205928343296	0.0241807818742503	0.0172448879434105	RHOA/MYH9/IKBKB/CHUK/EEF1A1/AP2A1/PPP3CA/ALOX15	8
CC	GO:0032154	cleavage furrow	4/233	54/19960	0.0740740740740741	6.34557304085201	4.27480171929621	0.00362412390910489	0.0257173408165328	0.0183407080420288	RHOA/HTR3A/MYH9/ITGB1	4
CC	GO:0016363	nuclear matrix	6/233	129/19960	0.0465116279069767	3.9844295837908	3.69573405261843	0.004098299262807	0.0285334420372789	0.020349052943431	PRKCD/SMARCA4/TP53/LMNA/PRKCZ/ALOX5	6
CC	GO:0035579	specific granule membrane	5/233	91/19960	0.0549450549450549	4.70688110173089	3.8517507414059	0.0042795896303451	0.0292438624740249	0.0208556999529488	ITGAL/ITGB2/PLAU/PLAUR/OLR1	5
CC	GO:0090734	site of DNA damage	6/233	131/19960	0.0458015267175573	3.92359859777872	3.64854589548557	0.0044174852541095	0.0296373101593892	0.0211362930818636	DDB1/ATM/ATR/RPA1/TP53/LMNA	6
CC	GO:0045211	postsynaptic membrane	10/233	321/19960	0.0311526479750779	2.6686989424144	3.27557576425865	0.00461612738320293	0.0299740343055933	0.0213764329664764	HTR3A/KCNA2/NRP2/HTR3B/EPHB2/HTR2A/HSPA8/NRP1/SLC6A4/SLC6A3	10
CC	GO:0030017	sarcomere	8/233	222/19960	0.036036036036036	3.08703553338747	3.39837723273637	0.00466634005527819	0.0299740343055933	0.0213764329664764	MMP2/TPM3/PDE4B/ALDOA/FLNA/MYH7/PPP3CA/PLEC	8
CC	GO:0044306	neuron projection terminus	6/233	133/19960	0.0451127819548872	3.86459711510536	3.60228188979807	0.00475465118592642	0.0299740343055933	0.0213764329664764	NTRK2/SNCA/KCNA2/PDYN/HSPA8/SLC6A3	6
CC	GO:0005741	mitochondrial outer membrane	8/233	223/19960	0.0358744394618834	3.07319232471757	3.38351635913533	0.00479259627108402	0.0299740343055933	0.0213764329664764	MAOA/MAOB/PLA2G2A/BPHL/RAF1/BCL2L1/BCL2/PLEC	8
CC	GO:0032432	actin filament bundle	5/233	95/19960	0.0526315789473684	4.50869663428959	3.7254622367946	0.0051362695113437	0.0315880574947637	0.0225274978567706	TPM3/MYH9/FLNA/MYH7/PRKCZ	5
CC	GO:0034703	cation channel complex	8/233	228/19960	0.0350877192982456	3.00579775619306	3.31044089666662	0.00546365771395509	0.0330506507614661	0.023570568222412	PDE4D/PDE4B/HTR3A/KCNA2/KCNQ2/KCNQ5/KCNQ4/HTR3B	8
CC	GO:0097136	Bcl-2 family protein complex	2/233	10/19960	0.2	17.1330472103004	5.54576907912204	0.00574027882675191	0.0341639175334105	0.0243645111492016	BCL2L1/BCL2	2
CC	GO:0035861	site of double-strand break	5/233	99/19960	0.0505050505050505	4.32652707330819	3.60599343112209	0.00610786087191676	0.0357746136783696	0.025513203307923	DDB1/ATM/RPA1/TP53/LMNA	5
CC	GO:0042383	sarcolemma	6/233	144/19960	0.0416666666666667	3.56938483547926	3.36294088466143	0.00695669374147994	0.0389248457664096	0.0277598386581156	ITGB1/COL6A1/COL6A2/COL6A3/PPP3CA/PLEC	6
CC	GO:0035631	CD40 receptor complex	2/233	11/19960	0.181818181818182	15.5754974639095	5.25503957440117	0.00696216753545538	0.0389248457664096	0.0277598386581156	IKBKB/CHUK	2
CC	GO:1904090	peptidase inhibitor complex	2/233	11/19960	0.181818181818182	15.5754974639095	5.25503957440117	0.00696216753545538	0.0389248457664096	0.0277598386581156	PLAU/PLAT	2
CC	GO:0097060	synaptic membrane	12/233	453/19960	0.0264900662251656	2.26927777619873	2.96980109045811	0.00718734987525835	0.0395840612532885	0.0282299680882103	HTR3A/ITGB1/KCNA2/NRP2/HTR3B/EPHB2/HTR2A/HSPA8/NRP1/SLC6A4/SLC6A3/ADORA3	12
CC	GO:0031674	I band	6/233	148/19960	0.0405405405405405	3.4729149750609	3.28165339850674	0.00791572307163415	0.0429544384328383	0.0306336032183984	PDE4B/ALDOA/FLNA/MYH7/PPP3CA/PLEC	6
CC	GO:0032153	cell division site	4/233	68/19960	0.0588235294117647	5.0391315324413	3.62593533304511	0.00822430482638238	0.0439821518976101	0.0313665325186208	RHOA/HTR3A/MYH9/ITGB1	4
CC	GO:0008180	COP9 signalosome	3/233	36/19960	0.0833333333333333	7.13876967095851	4.00646312542188	0.008441694097037	0.0444997874543807	0.0317356920941241	MYH9/HSPA1A/HSPA5	3
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	9/233	302/19960	0.0298013245033113	2.55293749822357	2.95532066269512	0.00928966734286448	0.0482801021058731	0.0344316802923072	CDK2/CCNA2/IKBKB/CHUK/CDK1/TGFBR1/POLD3/POLR1A/PRKCZ	9
CC	GO:0031904	endosome lumen	3/233	38/19960	0.0789473684210526	6.76304495143438	3.86450759178617	0.00980550660988917	0.0495648210828644	0.0353478969354332	LNPEP/IL12B/INS	3
CC	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	3/233	38/19960	0.0789473684210526	6.76304495143438	3.86450759178617	0.00980550660988917	0.0495648210828644	0.0353478969354332	CRBN/DDB1/CDKN1B	3
MF	GO:0005201	extracellular matrix structural constituent	29/233	166/18737	0.174698795180723	14.0486322974301	18.9489426627225	4.36897801475305e-25	1.50657661671701e-22	1.01207347840703e-22	LAMA1/FGA/FGB/FGG/COL1A2/COL1A1/COL2A1/COL3A1/COL4A1/COL5A1/COL6A1/COL11A1/COL18A1/COL27A1/COL4A2/COL5A2/COL6A2/COL11A2/COL4A3/COL6A3/COL4A4/COL4A5/COL4A6/LAMA3/LAMA4/LAMA5/LAMB1/LAMB2/LAMB3	29
MF	GO:0030020	extracellular matrix structural constituent conferring tensile strength	19/233	45/18737	0.422222222222222	33.9535526943252	24.8350021871321	5.4784604244255e-25	1.50657661671701e-22	1.01207347840703e-22	COL1A2/COL1A1/COL2A1/COL3A1/COL4A1/COL5A1/COL6A1/COL11A1/COL18A1/COL27A1/COL4A2/COL5A2/COL6A2/COL11A2/COL4A3/COL6A3/COL4A4/COL4A5/COL4A6	19
MF	GO:0048407	platelet-derived growth factor binding	10/233	11/18737	0.909090909090909	73.1057354662505	26.8427640232084	7.92915966953232e-19	1.45367927274759e-16	9.76538611931875e-17	PDGFRB/PDGFRA/COL1A2/COL1A1/COL2A1/COL3A1/COL4A1/COL5A1/COL6A1/PDGFA	10
MF	GO:0019838	growth factor binding	20/233	132/18737	0.151515151515152	12.1842892443751	14.4698526310246	2.3400208112936e-16	3.2175286155287e-14	2.16144027569488e-14	KDR/NTRK1/NTRK2/PDGFRB/PDGFRA/SHC1/NRP2/HTRA1/NTRK3/COL1A2/COL1A1/COL2A1/COL3A1/COL4A1/COL5A1/COL6A1/TGFBR1/PDGFA/NRP1/FLT1	20
MF	GO:0004714	transmembrane receptor protein tyrosine kinase activity	14/233	60/18737	0.233333333333333	18.7638054363376	15.464705823527	1.49349429126275e-14	1.64284372038902e-12	1.10361367628047e-12	KDR/NTRK1/NTRK2/PDGFRB/PDGFRA/DDR1/NRP2/EPHB2/EPHB3/EPHB1/EPHB4/NTRK3/NRP1/FLT1	14
MF	GO:0019199	transmembrane receptor protein kinase activity	15/233	79/18737	0.189873417721519	15.2689194328245	14.2611870640248	4.45604754373038e-14	4.08471024841952e-12	2.74398717166555e-12	KDR/NTRK1/NTRK2/PDGFRB/PDGFRA/DDR1/NRP2/EPHB2/EPHB3/EPHB1/EPHB4/NTRK3/TGFBR1/NRP1/FLT1	15
MF	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	10/233	23/18737	0.434782608695652	34.9636126142937	18.2884994528	7.23730583866047e-14	5.68645458751894e-12	3.81999150281177e-12	PDE5A/PDE4A/PDE3A/PDE6H/PDE4D/PDE4B/PDE6A/PDE3B/PDE6C/PDE8B	10
MF	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	10/233	24/18737	0.416666666666667	33.5067954220315	17.8809940899027	1.2272576850335e-13	7.49990807520472e-12	5.03821575961121e-12	PDE5A/PDE4A/PDE3A/PDE6H/PDE4D/PDE4B/PDE6A/PDE3B/PDE6C/PDE8B	10
MF	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	10/233	24/18737	0.416666666666667	33.5067954220315	17.8809940899027	1.2272576850335e-13	7.49990807520472e-12	5.03821575961121e-12	PDE5A/PDE4A/PDE3A/PDE6H/PDE4D/PDE4B/PDE6A/PDE3B/PDE6C/PDE8B	10
MF	GO:0005178	integrin binding	19/233	161/18737	0.118012422360248	9.49012342387972	12.1404400880152	1.46204260441614e-13	8.04123432428879e-12	5.40186267526386e-12	KDR/ITGA1/PRKCA/MYH9/ITGB1/ITGAL/ICAM1/ITGB2/ITGB7/MMP14/IGF2/COL3A1/COL5A1/COL4A3/LAMA5/LAMB2/ADAMTS5/PPIA/SLC6A4	19
MF	GO:0004112	cyclic-nucleotide phosphodiesterase activity	10/233	26/18737	0.384615384615385	30.9293496203367	17.1363784023101	3.25229376074909e-13	1.62614688037455e-11	1.0923972344717e-11	PDE5A/PDE4A/PDE3A/PDE6H/PDE4D/PDE4B/PDE6A/PDE3B/PDE6C/PDE8B	10
MF	GO:0004879	nuclear receptor activity	12/233	59/18737	0.203389830508475	16.3558594602459	13.2561844549371	6.88364610181898e-12	3.1550044633337e-10	2.11943840503374e-10	NR4A2/PDE3A/NR4A3/ESR1/RORA/THRA/ESR2/NR4A1/THRB/HNF4A/AHR/AR	12
MF	GO:0098531	ligand-activated transcription factor activity	12/233	60/18737	0.2	16.0832618025751	13.1310944308652	8.51089621554203e-12	3.60076378349855e-10	2.41888629283826e-10	NR4A2/PDE3A/NR4A3/ESR1/RORA/THRA/ESR2/NR4A1/THRB/HNF4A/AHR/AR	12
MF	GO:0004713	protein tyrosine kinase activity	16/233	138/18737	0.115942028985507	9.32363003047832	11.0126314137844	1.70500074283929e-11	6.69821720401149e-10	4.49966361456083e-10	KDR/NTRK1/NTRK2/PDGFRB/PDGFRA/DDR1/PRKCD/NRP2/EPHB2/EPHB3/EPHB1/EPHB4/NTRK3/NRP1/FLT1/DYRK1A	16
MF	GO:0008236	serine-type peptidase activity	17/233	195/18737	0.0871794871794872	7.01065258060966	9.46769443857379	3.73434949916349e-10	1.36926148302661e-08	9.19829245057112e-09	MMP2/MMP1/CTSA/MASP2/MMP9/PLAU/MMP8/MMP13/MMP3/HTRA1/MMP14/LTF/F2/GZMA/PLAT/CTRL/PLG	17
MF	GO:0017171	serine hydrolase activity	17/233	199/18737	0.085427135678392	6.86973494079841	9.34108188291627	5.12274162641004e-10	1.76094243407845e-08	1.18294888873021e-08	MMP2/MMP1/CTSA/MASP2/MMP9/PLAU/MMP8/MMP13/MMP3/HTRA1/MMP14/LTF/F2/GZMA/PLAT/CTRL/PLG	17
MF	GO:0004252	serine-type endopeptidase activity	16/233	178/18737	0.0898876404494382	7.22843227082027	9.36903909076416	7.95350866607318e-10	2.57319398020015e-08	1.72859538191436e-08	MMP2/MMP1/MASP2/MMP9/PLAU/MMP8/MMP13/MMP3/HTRA1/MMP14/LTF/F2/GZMA/PLAT/CTRL/PLG	16
MF	GO:0008237	metallopeptidase activity	16/233	185/18737	0.0864864864864865	6.95492402273518	9.13377503430316	1.4026464931572e-09	4.28586428464699e-08	2.87911648595424e-08	MMP2/MMP1/CPB2/MMP9/MMP8/MMP13/MMP3/ADAMTS4/ADAMTS1/ERAP1/MMP14/ANPEP/LNPEP/ERAP2/LTA4H/ADAMTS5	16
MF	GO:0002020	protease binding	14/233	136/18737	0.102941176470588	8.27814945720777	9.55885484903346	1.58923190280109e-09	4.60040813968737e-08	3.09041771680434e-08	NTRK2/ITGB1/PSAP/IL1R1/ADAMTS4/TP53/COL1A2/COL1A1/COL3A1/INS/TNF/PLG/BCL2/SLC6A3	14
MF	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	9/233	44/18737	0.204545454545455	16.4487904799064	11.5123744765183	2.95852273826144e-09	8.13593753021896e-08	5.46548147963035e-08	CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2R1/CYP2S1	9
MF	GO:0008081	phosphoric diester hydrolase activity	11/233	87/18737	0.126436781609195	10.1675793004785	9.61741757831859	1.06024211722554e-08	2.77682459273356e-07	1.86538838669757e-07	PDE5A/PDE4A/PDE3A/PDE6H/PDE4D/PDE4B/PDE6A/PDE3B/PDE6C/PDE8B/EDNRA	11
MF	GO:0008395	steroid hydroxylase activity	7/233	26/18737	0.269230769230769	21.6505447342357	11.8236965810724	2.26034906171918e-08	5.65087265429796e-07	3.79608861561451e-07	CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP1B1/CYP2R1	7
MF	GO:0004175	endopeptidase activity	21/233	404/18737	0.051980198019802	4.18005566651086	7.25090516759389	3.69967402695078e-08	8.84704658618664e-07	5.94318344832825e-07	MMP2/MMP1/MASP2/MMP9/PLAU/MMP8/MMP13/MMP3/ADAMTS4/ADAMTS1/HTRA1/ERAP1/MMP14/LTF/F2/ERAP2/ADAMTS5/GZMA/PLAT/CTRL/PLG	21
MF	GO:0005506	iron ion binding	13/233	153/18737	0.0849673202614379	6.83275828213975	8.12893564824572	6.26307808823042e-08	1.43528872855281e-06	9.64184389898631e-07	SNCA/CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2R1/CYP2S1/LTF/ALOX5/ALOX15	13
MF	GO:0031072	heat shock protein binding	12/233	131/18737	0.0916030534351145	7.36637945156112	8.20512589591663	8.87707530848105e-08	1.95295656786583e-06	1.31193828769552e-06	KDR/SNCA/APOA1/ITGB2/HSPA1A/CDK1/CDKN1B/HSPA5/CYP1A1/HSPA8/AHR/MAPT	12
MF	GO:0005161	platelet-derived growth factor receptor binding	5/233	14/18737	0.357142857142857	28.7201103617413	11.6427304713398	5.20482919600061e-07	1.10102156069244e-05	7.3963362258956e-06	VEGFA/PDGFRB/PDGFRA/IL1R1/PDGFA	5
MF	GO:0070006	metalloaminopeptidase activity	6/233	26/18737	0.230769230769231	18.557609772202	10.0528026406598	6.48211603656763e-07	1.27327279289721e-05	8.55346890539563e-06	ERAP1/MMP14/ANPEP/LNPEP/ERAP2/LTA4H	6
MF	GO:0070330	aromatase activity	6/233	26/18737	0.230769230769231	18.557609772202	10.0528026406598	6.48211603656763e-07	1.27327279289721e-05	8.55346890539563e-06	CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP1B1	6
MF	GO:0043176	amine binding	5/233	15/18737	0.333333333333333	26.8054363376252	11.2192623959601	7.72823238483202e-07	1.46569924539918e-05	9.84613272985858e-06	HTR3A/HTR1A/HTR2A/SLC6A4/SLC6A3	5
MF	GO:0051087	protein-folding chaperone binding	11/233	134/18737	0.082089552238806	6.60133879956441	7.30190767773107	9.32798208778471e-07	1.7101300494272e-05	1.14881463607454e-05	SNCA/CDK1/CDKN1B/HSPA5/CYP1A1/TP53/FGB/HSPA8/GRN/PLG/MAPT	11
MF	GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/233	16/18737	0.3125	25.1300965665236	10.8352296148315	1.11273315419428e-06	1.97420398324792e-05	1.3262116710431e-05	PRKCA/PRKCD/PRKCH/PRKCQ/PRKCZ	5
MF	GO:0004222	metalloendopeptidase activity	10/233	110/18737	0.0909090909090909	7.31057354662505	7.44864553080949	1.15380145207748e-06	1.98309624575817e-05	1.33218522920788e-05	MMP2/MMP1/MMP9/MMP8/MMP13/MMP3/ADAMTS4/ADAMTS1/MMP14/ADAMTS5	10
MF	GO:0020037	heme binding	11/233	143/18737	0.0769230769230769	6.18586992406735	6.98532817229724	1.776809868662e-06	2.96134978110334e-05	1.98934693429143e-05	CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2R1/CYP2S1/PTGS1/PTGS2	11
MF	GO:0005003	ephrin receptor activity	5/233	18/18737	0.277777777777778	22.3378636146877	10.1631761946457	2.13874183107015e-06	3.37171791457002e-05	2.26502007275422e-05	NTRK1/EPHB2/EPHB3/EPHB1/EPHB4	5
MF	GO:0008201	heparin binding	12/233	176/18737	0.0681818181818182	5.48293015996879	6.70503749864468	2.1517146417503e-06	3.37171791457002e-05	2.26502007275422e-05	VEGFA/NRP2/CXCL8/ADAMTS1/LTF/F2/COL5A1/COL11A1/COL11A2/ADAMTS5/PF4/NRP1	12
MF	GO:0005518	collagen binding	8/233	69/18737	0.115942028985507	9.32363003047832	7.77270181542974	2.20694263499129e-06	3.37171791457002e-05	2.26502007275422e-05	ITGA1/DDR1/ITGB1/MMP9/MMP13/COL6A1/COL6A2/PDGFA	8
MF	GO:0042562	hormone binding	9/233	93/18737	0.0967741935483871	7.78222345285892	7.35745493943174	2.36691224998295e-06	3.51838307429898e-05	2.36354537622764e-05	PDE3A/SHC1/INHBA/THRA/THRB/NPR2/NPR3/AR/SHBG	9
MF	GO:0046906	tetrapyrrole binding	11/233	153/18737	0.0718954248366013	5.7815647002721	6.66391951565256	3.44191554614092e-06	4.98171986941448e-05	3.34657162519518e-05	CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2R1/CYP2S1/PTGS1/PTGS2	11
MF	GO:0030551	cyclic nucleotide binding	6/233	37/18737	0.162162162162162	13.0404825426285	8.22635677106317	5.83816859520159e-06	8.2333146855407e-05	5.53089656387519e-05	PDE5A/PDE4A/PDE6H/PDE4D/PDE4B/PDE6C	6
MF	GO:0004497	monooxygenase activity	9/233	106/18737	0.0849056603773585	6.82779982184792	6.7518543479875	7.02675154336925e-06	9.18517104693544e-05	6.1703254305729e-05	CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2R1/CYP2S1	9
MF	GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	4/233	11/18737	0.363636363636364	29.2422941865002	10.5137439264743	7.18113372760407e-06	9.18517104693544e-05	6.1703254305729e-05	PDE5A/PDE6H/PDE6A/PDE6C	4
MF	GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	4/233	11/18737	0.363636363636364	29.2422941865002	10.5137439264743	7.18113372760407e-06	9.18517104693544e-05	6.1703254305729e-05	PDE5A/PDE6H/PDE6A/PDE6C	4
MF	GO:0051378	serotonin binding	4/233	11/18737	0.363636363636364	29.2422941865002	10.5137439264743	7.18113372760407e-06	9.18517104693544e-05	6.1703254305729e-05	HTR3A/HTR1A/HTR2A/SLC6A4	4
MF	GO:0004674	protein serine/threonine kinase activity	18/233	429/18737	0.041958041958042	3.3741108676731	5.58203788569346	7.53112321435737e-06	9.41390401794671e-05	6.32398145511827e-05	CDC7/CDK2/PRKCA/PRKCD/PRKCH/PRKCQ/IKBKB/CHUK/ATM/ATR/CDK1/NEK4/BRD4/RAF1/BRAF/TGFBR1/PRKCZ/DYRK1A	18
MF	GO:0005496	steroid binding	9/233	108/18737	0.0833333333333333	6.70135908440629	6.66774666118488	8.19155487696645e-06	0.000100119004051812	6.72569768845666e-05	APOA1/ESR1/RORA/ESR2/CYP3A4/CYP2R1/ABCA1/AR/SHBG	9
MF	GO:0004177	aminopeptidase activity	6/233	40/18737	0.15	12.0624463519313	7.85920828681617	9.34363504082868e-06	0.000111717375488169	7.50484187489901e-05	ERAP1/MMP14/ANPEP/LNPEP/ERAP2/LTA4H	6
MF	GO:1901681	sulfur compound binding	14/233	277/18737	0.0505415162454874	4.06436218837638	5.76564263544426	1.02506459539776e-05	0.000119954367546546	8.05817856628471e-05	VEGFA/HMGCR/NRP2/CXCL8/ADAMTS1/LTF/F2/COL5A1/COL11A1/COL11A2/ADAMTS5/PPIA/PF4/NRP1	14
MF	GO:0005539	glycosaminoglycan binding	13/233	246/18737	0.0528455284552846	4.24964234620887	5.75713626911549	1.32973233364454e-05	0.000152365163230104	0.000102354396734481	VEGFA/NRP2/CXCL8/ADAMTS1/LTF/F2/COL5A1/COL11A1/COL11A2/ADAMTS5/PPIA/PF4/NRP1	13
MF	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	11/233	180/18737	0.0611111111111111	4.91432999523128	5.92138629209371	1.62289655386076e-05	0.000182161858086412	0.000122370932417858	CYP3A4/CYP1A1/CYP1A2/CYP2C9/CYP2C19/CYP2D6/CYP1B1/CYP2R1/CYP2S1/PTGS1/PTGS2	11
MF	GO:0008235	metalloexopeptidase activity	7/233	67/18737	0.104477611940299	8.40170392671834	6.81052420687504	1.93816089608999e-05	0.000213197698569898	0.000143219889374228	CPB2/ERAP1/MMP14/ANPEP/LNPEP/ERAP2/LTA4H	7
MF	GO:0099589	serotonin receptor activity	4/233	15/18737	0.266666666666667	21.4443490701001	8.88845721231329	2.8562314251334e-05	0.000308024957612425	0.000206922028941553	HTR3A/HTR3B/HTR1A/HTR2A	4
MF	GO:0008238	exopeptidase activity	8/233	103/18737	0.0776699029126214	6.2459269136214	5.99061475676881	4.36847663986465e-05	0.000462050413831838	0.000310391761253541	CPB2/CTSA/ERAP1/MMP14/ANPEP/LNPEP/ERAP2/LTA4H	8
MF	GO:0106310	protein serine kinase activity	15/233	363/18737	0.0413223140495868	3.32298797573866	5.01512783721763	5.22956652291764e-05	0.000542690865585793	0.000364563624537059	CDC7/CDK2/PRKCA/PRKCD/PRKCH/PRKCQ/IKBKB/ATM/ATR/CDK1/NEK4/RAF1/BRAF/PRKCZ/DYRK1A	15
MF	GO:0001618	virus receptor activity	7/233	79/18737	0.0886075949367089	7.12549573531809	6.12217631142413	5.69415508185797e-05	0.000579960239818867	0.000389600084548177	ITGB1/ICAM1/ITGB7/HSPA1A/CDK1/ANPEP/HTR2A	7
MF	GO:0140272	exogenous protein binding	7/233	80/18737	0.0875	7.03642703862661	6.07138303793499	6.17492703691865e-05	0.000610674850056069	0.000410233248554412	ITGB1/ICAM1/ITGB7/HSPA1A/CDK1/ANPEP/HTR2A	7
MF	GO:0008391	arachidonate monooxygenase activity	4/233	18/18737	0.222222222222222	17.8702908917501	8.03528140791772	6.21778029147998e-05	0.000610674850056069	0.000410233248554412	CYP1A1/CYP2C9/CYP2C19/CYP2S1	4
MF	GO:0019955	cytokine binding	9/233	143/18737	0.0629370629370629	5.06116630150965	5.4703607675662	7.66725156242212e-05	0.000739822519181082	0.000496990821497722	ITGB1/NRP2/MMP8/IL18R1/IL12B/CXCR1/TGFBR1/NRP1/CXCR2	9
MF	GO:0140375	immune receptor activity	9/233	154/18737	0.0584415584415584	4.69965442283039	5.17305619123005	0.000135292605472923	0.00128294712086393	0.00086184581707797	IL1R1/FCGR2A/IL17RA/IL18R1/IL12B/CXCR1/KLRK1/FCGR3A/CXCR2	9
MF	GO:0001091	RNA polymerase II general transcription initiation factor binding	4/233	24/18737	0.166666666666667	13.4027181688126	6.82235598421863	0.000203626476862558	0.00186657603790679	0.00125391041015365	ESR1/TP53/AHR/AR	4
MF	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	4/233	24/18737	0.166666666666667	13.4027181688126	6.82235598421863	0.000203626476862558	0.00186657603790679	0.00125391041015365	ALOX5/PTGS1/ALOX15/PTGS2	4
MF	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	3/233	10/18737	0.3	24.1248927038627	8.20784621215906	0.000213566671119789	0.00188704670145155	0.00126766199465932	CDK1/BRD4/DYRK1A	3
MF	GO:0043121	neurotrophin binding	3/233	10/18737	0.3	24.1248927038627	8.20784621215906	0.000213566671119789	0.00188704670145155	0.00126766199465932	NTRK1/NTRK2/NTRK3	3
MF	GO:0002039	p53 binding	6/233	69/18737	0.0869565217391304	6.99272252285874	5.59607347542261	0.000216152622166268	0.00188704670145155	0.00126766199465932	SMARCA4/TP53/CDKN2A/MDM2/BRD4/NTRK3	6
MF	GO:0001223	transcription coactivator binding	5/233	45/18737	0.111111111111111	8.93514544587506	5.9802157397571	0.000232017553186931	0.00199390084770019	0.00133944344027323	ESR1/RORA/THRB/AHR/AR	5
MF	GO:0003707	nuclear steroid receptor activity	4/233	25/18737	0.16	12.8666094420601	6.66223792529716	0.00024005963393107	0.00200049694942559	0.00134387450573853	PDE3A/NR4A3/ESR1/ESR2	4
MF	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	4/233	25/18737	0.16	12.8666094420601	6.66223792529716	0.00024005963393107	0.00200049694942559	0.00134387450573853	ALOX5/PTGS1/ALOX15/PTGS2	4
MF	GO:0008046	axon guidance receptor activity	3/233	11/18737	0.272727272727273	21.9317206398751	7.79224057701863	0.000290961247641859	0.00231925632178293	0.00155800759606853	EPHB2/EPHB3/EPHB1	3
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	3/233	11/18737	0.272727272727273	21.9317206398751	7.79224057701863	0.000290961247641859	0.00231925632178293	0.00155800759606853	CYP3A4/CYP1A2/CYP2C9	3
MF	GO:0034056	estrogen response element binding	3/233	11/18737	0.272727272727273	21.9317206398751	7.79224057701863	0.000290961247641859	0.00231925632178293	0.00155800759606853	ESR1/ESR2/AR	3
MF	GO:0042277	peptide binding	11/233	249/18737	0.0441767068273092	3.55252770739611	4.54997239541341	0.000297808988601637	0.00233992776758429	0.00157189406013797	APOA1/ITGB2/ERAP1/EPHB2/ANPEP/LNPEP/ERAP2/HSPA8/MICA/HLA-A/NPR3	11
MF	GO:0070851	growth factor receptor binding	8/233	138/18737	0.0579710144927536	4.66181501523916	4.84478754108833	0.000336232294151224	0.00260461636314329	0.00174970400662831	VEGFA/PDGFRB/PDGFRA/SHC1/IL1R1/ERAP1/IL12B/PDGFA	8
MF	GO:0035173	histone kinase activity	11/233	256/18737	0.04296875	3.455388277897	4.43875338814968	0.000376903719901733	0.00284311779316395	0.00190992219215415	CDC7/CDK2/PRKCA/IKBKB/ATM/ATR/CDK1/NEK4/RAF1/BRAF/DYRK1A	11
MF	GO:0097718	disordered domain specific binding	4/233	28/18737	0.142857142857143	11.4880441446965	6.23206284718339	0.000377359270729033	0.00284311779316395	0.00190992219215415	HSPA1A/TP53/CDKN2A/MDM2	4
MF	GO:0035259	nuclear glucocorticoid receptor binding	3/233	12/18737	0.25	20.1040772532189	7.42829880461213	0.000384392786446339	0.00285697341277684	0.00191922998638215	NR4A2/NR4A3/NR4A1	3
MF	GO:0051721	protein phosphatase 2A binding	4/233	30/18737	0.133333333333333	10.7221745350501	5.98006021584792	0.000495340987418343	0.00363250057440118	0.00244020612749247	TP53/MAPT/BCL2/SLC6A3	4
MF	GO:0140296	general transcription initiation factor binding	5/233	53/18737	0.0943396226415094	7.58644424649769	5.38812441035675	0.000502752384565935	0.00363833962514821	0.00244412862856847	ESR1/THRA/TP53/AHR/AR	5
MF	GO:0042578	phosphoric ester hydrolase activity	13/233	363/18737	0.0358126721763085	2.87992291230684	4.05858912219954	0.000648903389771562	0.00463502421265401	0.00311367176773504	PDE5A/PDE4A/PDE3A/PDE6H/PDE4D/PDE4B/PDE6A/PDE3B/PDE6C/PDE8B/EDNRA/PON1/PPP3CA	13
MF	GO:0052689	carboxylic ester hydrolase activity	9/233	195/18737	0.0461538461538462	3.71152195444041	4.27106058515901	0.00076881586984669	0.00531685651764021	0.0035717064836205	EDNRA/PLA2G2A/PLA2G5/PLA2G10/BPHL/PON1/PON2/LIPA/CA2	9
MF	GO:0005005	transmembrane-ephrin receptor activity	3/233	15/18737	0.2	16.0832618025751	6.5576520286665	0.000773360948020394	0.00531685651764021	0.0035717064836205	EPHB2/EPHB3/EPHB1	3
MF	GO:0030553	cGMP binding	3/233	15/18737	0.2	16.0832618025751	6.5576520286665	0.000773360948020394	0.00531685651764021	0.0035717064836205	PDE5A/PDE6H/PDE6C	3
MF	GO:0001098	basal transcription machinery binding	5/233	60/18737	0.0833333333333333	6.70135908440629	4.96345455654882	0.000891783920837126	0.00597374275570461	0.00401298317177477	ESR1/TP53/BRD4/AHR/AR	5
MF	GO:0001099	basal RNA polymerase II transcription machinery binding	5/233	60/18737	0.0833333333333333	6.70135908440629	4.96345455654882	0.000891783920837126	0.00597374275570461	0.00401298317177477	ESR1/TP53/BRD4/AHR/AR	5
MF	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	4/233	35/18737	0.114285714285714	9.1904353157572	5.44227609158934	0.000901492088588151	0.00597374275570461	0.00401298317177477	CYP3A4/CYP1A1/CYP2D6/CYP1B1	4
MF	GO:0005159	insulin-like growth factor receptor binding	3/233	16/18737	0.1875	15.0780579399142	6.3215242379715	0.000943126049575011	0.00610258032077948	0.00409953242601646	SHC1/IGF2/INS	3
MF	GO:0008392	arachidonate epoxygenase activity	3/233	16/18737	0.1875	15.0780579399142	6.3215242379715	0.000943126049575011	0.00610258032077948	0.00409953242601646	CYP2C9/CYP2C19/CYP2S1	3
MF	GO:0016836	hydro-lyase activity	5/233	61/18737	0.0819672131147541	6.59150073876029	4.90834364342488	0.000961698401565285	0.00613601585879165	0.00412199342858539	CYP1A1/CYP1A2/CYP1B1/CYP2S1/CA2	5
MF	GO:0008083	growth factor activity	8/233	162/18737	0.0493827160493827	3.97117575372225	4.26191739489987	0.000970606144936133	0.00613601585879165	0.00412199342858539	VEGFA/INHBA/IGF2/F2/IL12B/PDGFA/GRN/HGF	8
MF	GO:0033218	amide binding	10/233	244/18737	0.040983606557377	3.29575036938014	4.05041460813992	0.000992395713336727	0.00620247320835455	0.0041666375045597	HMGCR/APOA1/PSAP/ITGB2/INHBA/EPHB2/PPIA/NPR2/NPR3/SRD5A1	10
MF	GO:0047498	calcium-dependent phospholipase A2 activity	3/233	17/18737	0.176470588235294	14.1911133552133	6.10571572744292	0.00113475967676809	0.00701255980025225	0.00471082964571969	PLA2G2A/PLA2G5/PLA2G10	3
MF	GO:0004896	cytokine receptor activity	6/233	97/18737	0.0618556701030928	4.9742046812088	4.40348714841731	0.00133581018888429	0.00815496514666278	0.00547826366790169	IL1R1/IL17RA/IL18R1/IL12B/CXCR1/CXCR2	6
MF	GO:0034185	apolipoprotein binding	3/233	18/18737	0.166666666666667	13.4027181688126	5.9073866211897	0.00134927605153875	0.00815496514666278	0.00547826366790169	ABCA1/PLG/MAPT	3
MF	GO:0097110	scaffold protein binding	5/233	70/18737	0.0714285714285714	5.74402207234825	4.46212823131543	0.00178760821368233	0.0106488575259693	0.00715358658682338	PDE4D/PSAP/IKBKB/CHUK/BRAF	5
MF	GO:0051879	Hsp90 protein binding	4/233	42/18737	0.0952380952380952	7.65869609646434	4.84768837324585	0.00180062499984571	0.0106488575259693	0.00715358658682338	KDR/CYP1A1/AHR/MAPT	4
MF	GO:0016004	phospholipase activator activity	3/233	20/18737	0.15	12.0624463519313	5.55432956207831	0.00185077692678311	0.0108290139333054	0.00727461031691905	PLAA/PDGFRB/PDGFRA	3
MF	GO:0019207	kinase regulator activity	10/233	273/18737	0.0366300366300366	2.94565234479398	3.63385219852055	0.00228188795665601	0.0132109302753769	0.00887471105580343	VEGFA/SNCA/CCNA2/PRKCH/CDKN1B/CDKN2A/AHSG/IGF2/LTF/HTR2A	10
MF	GO:0005126	cytokine receptor binding	10/233	277/18737	0.036101083032491	2.90311584884027	3.58074052730592	0.00253486322002066	0.0145226538647017	0.00975588805073739	VEGFA/NTRK1/SHC1/CXCL8/ERAP1/IL12B/TGFBR1/PF4/TNFSF13/TNF	10
MF	GO:0005158	insulin receptor binding	3/233	23/18737	0.130434782608696	10.4890837842881	5.1096185075286	0.00279733064945031	0.0156993046652823	0.010546327153137	SHC1/IGF2/INS	3
MF	GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	3/233	23/18737	0.130434782608696	10.4890837842881	5.1096185075286	0.00279733064945031	0.0156993046652823	0.010546327153137	CDK1/BRD4/DYRK1A	3
MF	GO:0016835	carbon-oxygen lyase activity	5/233	79/18737	0.0632911392405063	5.08963981094149	4.08742362327396	0.0030421790629657	0.0167319848463113	0.0112400510642206	CYP1A1/CYP1A2/CYP1B1/CYP2S1/CA2	5
MF	GO:0046332	SMAD binding	5/233	79/18737	0.0632911392405063	5.08963981094149	4.08742362327396	0.0030421790629657	0.0167319848463113	0.0112400510642206	FLNA/COL1A2/COL3A1/COL5A2/TGFBR1	5
MF	GO:0030552	cAMP binding	3/233	24/18737	0.125	10.0520386266094	4.97924963327128	0.00316785981696284	0.0170815970522506	0.0114749101728994	PDE4A/PDE4D/PDE4B	3
MF	GO:0060229	lipase activator activity	3/233	24/18737	0.125	10.0520386266094	4.97924963327128	0.00316785981696284	0.0170815970522506	0.0114749101728994	PLAA/PDGFRB/PDGFRA	3
MF	GO:0001221	transcription coregulator binding	6/233	117/18737	0.0512820512820513	4.12391328271157	3.80351954034609	0.00344534930704304	0.0183666755135728	0.0123381877612709	ESR1/RORA/SMARCA4/THRB/AHR/AR	6
MF	GO:0019887	protein kinase regulator activity	9/233	243/18737	0.037037037037037	2.97838181529169	3.48322405648492	0.00347297136983921	0.0183666755135728	0.0123381877612709	VEGFA/SNCA/CCNA2/PRKCH/CDKN1B/CDKN2A/IGF2/LTF/HTR2A	9
MF	GO:0017025	TBP-class protein binding	3/233	25/18737	0.12	9.64995708154506	4.85632163106379	0.00356710529646717	0.0185462173969772	0.0124587986724191	ESR1/THRA/AHR	3
MF	GO:0019210	kinase inhibitor activity	5/233	82/18737	0.0609756097560976	4.90343347639485	3.97502323329354	0.00357436189832651	0.0185462173969772	0.0124587986724191	SNCA/PRKCH/CDKN1B/CDKN2A/AHSG	5
MF	GO:0030544	Hsp70 protein binding	4/233	51/18737	0.0784313725490196	6.30716149120592	4.25865842793621	0.00368517309871925	0.0189424785448186	0.0127249951564236	SNCA/CDK1/CDKN1B/CYP1A1	4
MF	GO:0051117	ATPase binding	5/233	84/18737	0.0595238095238095	4.78668506029021	3.90308557823704	0.00396431251964591	0.0201886285722708	0.013562121777736	PDE4D/ESR1/ABCA1/PPP3CA/AR	5
MF	GO:0046982	protein heterodimerization activity	11/233	363/18737	0.0303030303030303	2.43685784887502	3.10205040718145	0.00592539429745126	0.0298094456534072	0.0200251012906142	HEXA/NR4A2/ITGB1/IKBKB/CHUK/TP53/NR4A1/IL12B/PDGFA/AHR/BCL2	11
MF	GO:0016798	hydrolase activity, acting on glycosyl bonds	6/233	131/18737	0.0458015267175573	3.68318972578056	3.45815226223453	0.00596904714413523	0.0298094456534072	0.0200251012906142	HEXA/IL1R1/GLA/IL18R1/MAN2B1/MANBA	6
MF	GO:0001968	fibronectin binding	3/233	30/18737	0.1	8.04163090128755	4.33127143065203	0.00601608812277854	0.0298094456534072	0.0200251012906142	VEGFA/MMP2/ITGB1	3
MF	GO:0001094	TFIID-class transcription factor complex binding	2/233	10/18737	0.2	16.0832618025751	5.35358562907366	0.0064878880327163	0.0310290297216867	0.0208443816886354	TP53/AHR	2
MF	GO:0008401	retinoic acid 4-hydroxylase activity	2/233	10/18737	0.2	16.0832618025751	5.35358562907366	0.0064878880327163	0.0310290297216867	0.0208443816886354	CYP3A4/CYP2S1	2
MF	GO:0043208	glycosphingolipid binding	2/233	10/18737	0.2	16.0832618025751	5.35358562907366	0.0064878880327163	0.0310290297216867	0.0208443816886354	PSAP/LAMA1	2
MF	GO:0070513	death domain binding	2/233	10/18737	0.2	16.0832618025751	5.35358562907366	0.0064878880327163	0.0310290297216867	0.0208443816886354	BCL2L1/BCL2	2
MF	GO:0030296	protein tyrosine kinase activator activity	3/233	32/18737	0.09375	7.53902896995708	4.15425339842427	0.00721717357671617	0.03363936836605	0.0225979297540355	VEGFA/IGF2/HTR2A	3
MF	GO:0071813	lipoprotein particle binding	3/233	32/18737	0.09375	7.53902896995708	4.15425339842427	0.00721717357671617	0.03363936836605	0.0225979297540355	APOA1/ABCA1/MAPT	3
MF	GO:0071814	protein-lipid complex binding	3/233	32/18737	0.09375	7.53902896995708	4.15425339842427	0.00721717357671617	0.03363936836605	0.0225979297540355	APOA1/ABCA1/MAPT	3
MF	GO:0003953	NAD+ nucleosidase activity	2/233	11/18737	0.181818181818182	14.6211470932501	5.07073722756295	0.00786498287384396	0.0354662345689584	0.0238251642750324	IL1R1/IL18R1	2
MF	GO:0019864	IgG binding	2/233	11/18737	0.181818181818182	14.6211470932501	5.07073722756295	0.00786498287384396	0.0354662345689584	0.0238251642750324	FCGR2A/FCGR3A	2
MF	GO:0019956	chemokine binding	3/233	33/18737	0.0909090909090909	7.31057354662505	4.0713847455683	0.00786705566802351	0.0354662345689584	0.0238251642750324	ITGB1/CXCR1/CXCR2	3
MF	GO:0071889	14-3-3 protein binding	3/233	33/18737	0.0909090909090909	7.31057354662505	4.0713847455683	0.00786705566802351	0.0354662345689584	0.0238251642750324	ESR1/TP53/PRKCZ	3
MF	GO:0019825	oxygen binding	3/233	34/18737	0.0882352941176471	7.09555667760667	3.9919104004197	0.00855035856322755	0.0379249774981867	0.0254768748361025	CYP3A4/CYP1A1/CYP2C19	3
MF	GO:0030332	cyclin binding	3/233	34/18737	0.0882352941176471	7.09555667760667	3.9919104004197	0.00855035856322755	0.0379249774981867	0.0254768748361025	CDK2/CDK1/CDKN1B	3
MF	GO:0050840	extracellular matrix binding	4/233	65/18737	0.0615384615384615	4.94869593925388	3.57847956566831	0.00872599916747102	0.0383943963368725	0.025792216486588	VEGFA/ITGB1/COL11A1/ADAMTS5	4
MF	GO:0005543	phospholipid binding	13/233	494/18737	0.0263157894736842	2.11621865823357	2.82129313831523	0.0091354715265084	0.0384224290315516	0.0258110480192815	SNCA/APOA1/PSAP/SHC1/PLA2G2A/PLA2G5/PLA2G10/MAP1LC3A/ABCA1/HSPA8/PON1/MAPT/ALOX15	13
MF	GO:0004623	phospholipase A2 activity	3/233	35/18737	0.0857142857142857	6.8928264868179	3.91559025432931	0.00926743979522499	0.0384224290315516	0.0258110480192815	PLA2G2A/PLA2G5/PLA2G10	3
MF	GO:0019903	protein phosphatase binding	6/233	144/18737	0.0416666666666667	3.35067954220315	3.17748514303864	0.00932628959499278	0.0384224290315516	0.0258110480192815	ITGA1/CDKN1B/TP53/MAPT/BCL2/SLC6A3	6
MF	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/233	12/18737	0.166666666666667	13.4027181688126	4.82258814839164	0.00936110089132348	0.0384224290315516	0.0258110480192815	CDKN1B/CDKN2A	2
MF	GO:0005165	neurotrophin receptor binding	2/233	12/18737	0.166666666666667	13.4027181688126	4.82258814839164	0.00936110089132348	0.0384224290315516	0.0258110480192815	NTRK1/SHC1	2
MF	GO:0008504	monoamine transmembrane transporter activity	2/233	12/18737	0.166666666666667	13.4027181688126	4.82258814839164	0.00936110089132348	0.0384224290315516	0.0258110480192815	SLC6A4/SLC6A3	2
MF	GO:0097371	MDM2/MDM4 family protein binding	2/233	12/18737	0.166666666666667	13.4027181688126	4.82258814839164	0.00936110089132348	0.0384224290315516	0.0258110480192815	TP53/CDKN2A	2
MF	GO:0140996	histone H3 kinase activity	2/233	12/18737	0.166666666666667	13.4027181688126	4.82258814839164	0.00936110089132348	0.0384224290315516	0.0258110480192815	PRKCA/DYRK1A	2
MF	GO:1990459	transferrin receptor binding	2/233	12/18737	0.166666666666667	13.4027181688126	4.82258814839164	0.00936110089132348	0.0384224290315516	0.0258110480192815	IKBKB/CHUK	2
MF	GO:0004869	cysteine-type endopeptidase inhibitor activity	3/233	36/18737	0.0833333333333333	6.70135908440629	3.84220753597321	0.0100186272522641	0.0406006137571315	0.0272742879019199	XIAP/AHSG/LTF	3
MF	GO:0005125	cytokine activity	8/233	238/18737	0.0336134453781513	2.70306921051683	2.96708671689362	0.0100394244926725	0.0406006137571315	0.0272742879019199	VEGFA/INHBA/CXCL8/IL12B/PF4/TNFSF13/GRN/TNF	8
MF	GO:0004993	G protein-coupled serotonin receptor activity	2/233	13/18737	0.153846153846154	12.3717398481347	4.60238414798034	0.01097309496528	0.0428028527014469	0.0287536866951346	HTR1A/HTR2A	2
MF	GO:0008035	high-density lipoprotein particle binding	2/233	13/18737	0.153846153846154	12.3717398481347	4.60238414798034	0.01097309496528	0.0428028527014469	0.0287536866951346	APOA1/ABCA1	2
MF	GO:0017154	semaphorin receptor activity	2/233	13/18737	0.153846153846154	12.3717398481347	4.60238414798034	0.01097309496528	0.0428028527014469	0.0287536866951346	NRP2/NRP1	2
MF	GO:0043560	insulin receptor substrate binding	2/233	13/18737	0.153846153846154	12.3717398481347	4.60238414798034	0.01097309496528	0.0428028527014469	0.0287536866951346	PRKCD/PRKCZ	2
MF	GO:0120283	protein serine/threonine kinase binding	2/233	13/18737	0.153846153846154	12.3717398481347	4.60238414798034	0.01097309496528	0.0428028527014469	0.0287536866951346	PRKCH/XIAP	2
MF	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	10/233	349/18737	0.0286532951289398	2.30419223532595	2.75975586954057	0.0122852238898556	0.0475836136578915	0.0319652600840573	NR4A2/NR4A3/ESR1/SMARCA4/TP53/CDKN2A/NR4A1/HNF4A/AHR/AR	10
MF	GO:0019763	immunoglobulin receptor activity	2/233	14/18737	0.142857142857143	11.4880441446965	4.40508603878964	0.0126978772559489	0.0488379894459574	0.0328079125273321	FCGR2A/FCGR3A	2
MF	GO:0016829	lyase activity	7/233	201/18737	0.0348258706467662	2.80056797557278	2.87993794152326	0.0130645755011739	0.0498994203169836	0.0335209502990646	CYP1A1/CYP1A2/CYP1B1/CYP2S1/ALDOA/NPR2/CA2	7