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[null,"Table S5 Coefficient of regression lines between the relative areas of the metabolites and age."]
[null,"Metabolite","Control","Oral cancer","Breast cancer","Pancreatic cancer","Periodontal diseases"]
[null,"59.0616 m/z","2.42× 10-4","2.81× 10-6","6.52× 10-7","4.31× 10-4","2.30× 10-4"]
[null,"214.4440 m/z","1.34× 10-4","-1.56× 10-4","-4.50× 10-5","2.24× 10-5","-1.46× 10-6"]
[null,"90.0553 m/z","1.57× 10-4","1.60× 10-4","-2.04× 10-4","4.80× 10-5","-2.49× 10-4"]
[null,"131.1174 m/z","1.67× 10-4","-2.84× 10-4","-1.14× 10-4",{"v":0.0011074146751028518,"d":"0.00111"},"-1.65× 10-6"]
[null,"104.0705 m/z","4.18× 10-5","1.09× 10-4","-9.56× 10-5","4.86× 10-4","-1.96× 10-5"]
[null,"Cadaverine","6.06× 10-4",{"v":-0.004797767256119604,"d":"-0.00480"},"5.12× 10-4","8.65× 10-4","2.97× 10-5"]
[null,"118.0864 m/z, 10.05 min.",{"v":0.01694625570900878,"d":"0.0169"},{"v":-0.01641224198958155,"d":"-0.0164"},{"v":-0.03194242031272231,"d":"-0.0319"},{"v":0.025677429155443184,"d":"0.0257"},{"v":0.00834819985433668,"d":"0.00835"}]
[null,"409.2312 m/z","-9.13× 10-6","-5.18× 10-5","-8.79× 10-4","-4.01× 10-5","1.19× 10-4"]
[null,"437.7442 m/z","2.44× 10-4","-6.44× 10-4","-9.85× 10-4","8.16× 10-4","-5.73× 10-4"]
[null,"215.1269 m/z","1.14× 10-4","-5.05× 10-5","-4.27× 10-4",{"v":-0.0010921519264816394,"d":"-0.00109"},"-1.27× 10-6"]
[null,"alpha-Aminobutyric acid","6.26× 10-5","-9.67× 10-5","-1.32× 10-4","4.21× 10-6","-2.21× 10-4"]
[null,"Alanine",{"v":0.001225825426002494,"d":"0.00123"},{"v":-0.005527456994228235,"d":"-0.00553"},{"v":-0.0017864383815588206,"d":"-0.00179"},{"v":0.0039056081361974753,"d":"0.00391"},{"v":-0.0019790624967941242,"d":"-0.00198"}]
[null,"Putrescine",{"v":0.0035032832374483165,"d":"0.00350"},{"v":-0.01307217780215176,"d":"-0.0131"},{"v":-0.001004561181112811,"d":"-0.00100"},{"v":0.006862385601304276,"d":"0.00686"},"-9.55× 10-4"]
[null,"Methylimidazoleacetic acid","7.19× 10-5","-3.38× 10-4","1.92× 10-5","2.58× 10-4","1.52× 10-5"]
[null,"Trimethylamine","7.41× 10-5","-2.74× 10-5","1.77× 10-4","4.03× 10-4","2.68× 10-4"]
[null,"145.1332 m/z","6.59× 10-5","-5.73× 10-4","1.74× 10-4","-6.74× 10-5","1.13× 10-4"]
[null,"Piperidine","5.99× 10-5",{"v":-0.004375150402561585,"d":"-0.00438"},"8.29× 10-5","7.09× 10-5","1.56× 10-5"]
[null,"Taurine","2.58× 10-5","-1.72× 10-5","2.47× 10-4","-2.52× 10-4",{"v":0,"d":"0.00"}]
[null,"Piperideine","-6.36× 10-5","4.33× 10-5","-3.96× 10-5","4.76× 10-5","-7.29× 10-6"]
[null,"Pipecolic acid","-1.24× 10-5","5.98× 10-5","-4.61× 10-5","2.53× 10-5","-1.14× 10-5"]
[null,"72.0813 m/z","-3.17× 10-5","-8.30× 10-5","-9.49× 10-5","-5.01× 10-5","-6.18× 10-5"]
[null,"120.0801 m/z","-8.27× 10-5","-1.45× 10-4","4.68× 10-5","9.77× 10-6","-2.32× 10-5"]
[null,"Pyrroline hydroxycarboxylic acid","-5.45× 10-5","-1.50× 10-4","-5.85× 10-5","9.47× 10-5","-1.52× 10-5"]
[null,"Betaine","-2.08× 10-5","-1.41× 10-4","-1.18× 10-5","2.75× 10-5","-1.36× 10-5"]
[null,"70.0655 m/z","-2.20× 10-4",{"v":-0.0018442135091496477,"d":"-0.00184"},"-1.61× 10-4","-4.24× 10-5","2.77× 10-5"]
[null,"139.0500 m/z","1.21× 10-4","-1.02× 10-4","1.14× 10-5","2.66× 10-6","1.42× 10-5"]
[null,"Leucine + Isoleucine","9.13× 10-4",{"v":-0.005210421648271557,"d":"-0.00521"},{"v":-0.00430372363042076,"d":"-0.00430"},"8.06× 10-5","-4.56× 10-4"]
[null,"Phenylalanine",{"v":0.0010467047002472051,"d":"0.00105"},{"v":-0.0022549244501905413,"d":"-0.00225"},"-9.56× 10-4","3.58× 10-4","-2.37× 10-4"]
[null,"Tyrosine",{"v":0.00130270159682571,"d":"0.00130"},{"v":-0.002154893985107685,"d":"-0.00215"},{"v":-0.0011024254811920606,"d":"-0.00110"},{"v":0.001142933547553846,"d":"0.00114"},"-2.07× 10-4"]
[null,"Histidine","6.78× 10-4","-6.90× 10-4","-2.58× 10-4","4.77× 10-4","-5.86× 10-5"]
[null,"Proline",{"v":0.007284819036676078,"d":"0.00728"},{"v":-0.01713003242517075,"d":"-0.0171"},{"v":-0.007988302522254374,"d":"-0.00799"},{"v":-0.0012631188140260553,"d":"-0.00126"},"7.56× 10-4"]
[null,"Lysine",{"v":0.002129159251318063,"d":"0.00213"},{"v":-0.0015578663271283491,"d":"-0.00156"},{"v":-0.0046699489733869025,"d":"-0.00467"},{"v":0.002926026171147991,"d":"0.00293"},"-5.16× 10-4"]
[null,"Glycine",{"v":0.005081826203102097,"d":"0.00508"},{"v":-0.006338864109783433,"d":"-0.00634"},{"v":-0.004950302982749405,"d":"-0.00495"},{"v":0.004568648314771179,"d":"0.00457"},{"v":-0.0016864543403474006,"d":"-0.00169"}]
[null,"Ornithine",{"v":0.001012309231913544,"d":"0.00101"},{"v":-0.001697032924016569,"d":"-0.00170"},"-4.58× 10-4","9.51× 10-4","-1.57× 10-4"]
[null,"367.1977 m/z","1.65× 10-4","-4.36× 10-4","-1.42× 10-4","-4.71× 10-6","-1.28× 10-4"]
[null,"Pro-Gly-Pro or Pro-Pro-Gly","6.51× 10-5","-2.42× 10-4","-4.20× 10-4","1.23× 10-4","8.59× 10-5"]
[null,"173.0919 m/z","3.74× 10-4","-8.97× 10-4","-8.12× 10-4","2.00× 10-4","-3.70× 10-4"]
[null,"Burimamide","6.90× 10-4",{"v":-0.002217045161997351,"d":"-0.00222"},{"v":-0.0017855283911977745,"d":"-0.00179"},"2.13× 10-4","-7.09× 10-4"]
[null,"Ethanolamine","4.91× 10-4","-9.37× 10-4","-1.91× 10-4",{"v":0.001467088665371731,"d":"0.00147"},"6.81× 10-4"]
[null,"gamma-Aminobutyric acid","4.61× 10-5","-6.91× 10-5","3.64× 10-5","1.36× 10-4","3.41× 10-5"]
[null,"Aspartic acid","4.97× 10-4","-5.19× 10-4","-1.15× 10-4",{"v":0.0012500738135802626,"d":"0.00125"},"-4.40× 10-4"]
[null,"Valine","5.34× 10-4",{"v":-0.00251838349955473,"d":"-0.00252"},{"v":-0.0016168565260694082,"d":"-0.00162"},"-4.25× 10-4","-6.38× 10-4"]
[null,"Tryptophan","4.53× 10-5","-8.36× 10-5","-1.61× 10-5","5.67× 10-5","-3.76× 10-5"]
[null,"beta-Alanine","7.33× 10-5","-8.77× 10-5","4.67× 10-5","2.20× 10-4","-2.11× 10-5"]
[null,"Citrulline","6.79× 10-4",{"v":-0.0012359560651805507,"d":"-0.00124"},"-4.21× 10-4","-1.87× 10-4","-5.51× 10-4"]
[null,"Glutamic acid","9.09× 10-4",{"v":-0.0029303293000506113,"d":"-0.00293"},{"v":-0.002747171397887908,"d":"-0.00275"},{"v":0.0035751190435098267,"d":"0.00358"},{"v":-0.0013874211028794589,"d":"-0.00139"}]
[null,"Threonine","1.42× 10-4","-3.80× 10-4","-2.45× 10-4","5.99× 10-4","-1.33× 10-4"]
[null,"Serine","4.09× 10-4","-8.04× 10-4","-4.69× 10-4",{"v":0.0011692001953738968,"d":"0.00117"},"-1.82× 10-4"]
[null,"Glutamine","8.02× 10-4",{"v":-0.0024956549494754626,"d":"-0.00250"},{"v":-0.0016478434864262144,"d":"-0.00165"},{"v":0.0028003750905987697,"d":"0.00280"},"-3.91× 10-4"]
[null,"Hypoxanthine","3.91× 10-5","-1.16× 10-4","6.59× 10-5","1.93× 10-4","-4.86× 10-6"]
[null,"Choline","7.33× 10-4",{"v":-0.001531580086158524,"d":"-0.00153"},"1.88× 10-4",{"v":0.0011223661206455147,"d":"0.00112"},"-1.87× 10-4"]
[null,"Carnitine","7.33× 10-5","-1.88× 10-4","6.65× 10-5","1.15× 10-4","1.12× 10-4"]
[null,"118.0863 m/z, 13.42 min.","1.81× 10-4",{"v":-0.001239657944042281,"d":"-0.00124"},"2.59× 10-4","4.35× 10-5","4.89× 10-7"]
[null,"Glycerophosphocholine","1.80× 10-5","-2.45× 10-5",{"v":0,"d":"0.00"},{"v":0,"d":"0.00"},{"v":0,"d":"0.00"}]
[null,"173.0285 m/z","-1.15× 10-4","1.30× 10-4","-8.15× 10-5","-5.58× 10-5","6.88× 10-6"]
[null,"288.9691 m/z","6.62× 10-4","-8.02× 10-5",{"v":0.001757797386848265,"d":"0.00176"},"5.97× 10-4",{"v":0,"d":"0.00"}]

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