{"text_format":"3","workbook":"xls","n_sheets":3,"sheets":["Sheet1","Sheet2","Sheet3"],"not_rendered":{"external_links":1,"defined_names":1},"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Sheet1","index":0,"n_rows":63,"n_cols":8,"rows_kept":63,"merged":[[1,1,1,7],[2,1,3,1],[2,2,2,4],[2,5,2,7],[3,3,3,4],[3,6,3,7]],"flags":["formulas_cached_only"]}
[]
[null,"Table S3. Comparison of salivary metabolite markers in samples from control subjects and subjects with oral cancer according to gender."]
[null,"Metabolite","Control",null,null,"Oral Cancer"]
[null,null,"M/F† ","p-value††",null,"M/F† ","p-value††"]
[null,"59.0616 m/z",{"v":0.7189699196499565,"d":"0.719"},{"v":0.21724601,"d":"0.217"},"",{"v":2.296993067740735,"d":"2.30"},{"v":0.50816375,"d":"0.508"},""]
[null,"214.4440 m/z",{"v":0.7126278955390356,"d":"0.713"},{"v":0.026052484,"d":"0.0261"},"*",{"v":0.8333806413587989,"d":"0.833"},{"v":0.272022,"d":"0.272"},""]
[null,"90.0553 m/z",{"v":0.9575055117000805,"d":"0.958"},{"v":0.34324723,"d":"0.343"},"",{"v":0.9980812514743975,"d":"0.998"},{"v":0.7033829,"d":"0.703"},""]
[null,"131.1174 m/z",{"v":0.8916307137579297,"d":"0.892"},{"v":0.9016434,"d":"0.902"},"",{"v":0.6463809457947818,"d":"0.646"},{"v":0.18325578,"d":"0.183"},""]
[null,"104.0706 m/z",{"v":0.7324906358378119,"d":"0.732"},{"v":0.13854471,"d":"0.139"},"",{"v":0.8625118136380712,"d":"0.863"},{"v":0.2850832,"d":"0.285"},""]
[null,"Cadaverine",{"v":0.6184600749848006,"d":"0.618"},{"v":0.9509802,"d":"0.951"},"",{"v":0.8568146232437678,"d":"0.857"},{"v":0.9053188,"d":"0.905"},""]
[null,"118.0864 m/z, 10.05 min.",{"v":0.9146627692782043,"d":"0.915"},{"v":0.8344341,"d":"0.834"},"",{"v":1.1120170092909927,"d":"1.11"},{"v":0.69006234,"d":"0.690"},""]
[null,"409.2312 m/z",{"v":18.21527792521758,"d":"18.2"},{"v":0.4259503,"d":"0.426"},"",{"v":0.9233279239880124,"d":"0.92"},{"v":0.6175069,"d":"0.618"},""]
[null,"437.7442 m/z",{"v":3.979590950099795,"d":"3.98"},{"v":0.23781984,"d":"0.238"},"",{"v":1.5329579626073728,"d":"1.53"},{"v":0.5461901,"d":"0.546"},""]
[null,"215.1269 m/z",{"v":0.5737202453635781,"d":"0.574"},{"v":0.34211785,"d":"0.342"},"",{"v":1.9361857160800569,"d":"1.94"},{"v":0.44565985,"d":"0.446"},""]
[null,"alpha-Aminobutyric acid",{"v":0.8271463560764107,"d":"0.827"},{"v":0.5695555,"d":"0.570"},"",{"v":0.5012361197410504,"d":"0.501"},{"v":0.6439531,"d":"0.644"},""]
[null,"Alanine",{"v":0.7884307221511918,"d":"0.788"},{"v":0.42418197,"d":"0.424"},"",{"v":0.4261992217371878,"d":"0.426"},{"v":0.27204397,"d":"0.272"},""]
[null,"Putrescine",{"v":0.7570397253219768,"d":"0.757"},{"v":0.8633333,"d":"0.863"},"",{"v":0.36521189863877207,"d":"0.365"},{"v":0.8228556,"d":"0.823"},""]
[null,"Methylimidazoleacetic acid",{"v":0.6251675722959955,"d":"0.625"},{"v":0.14790003,"d":"0.148"},"",{"v":0.31284525433523236,"d":"0.313"},{"v":0.2111257,"d":"0.211"},""]
[null,"Trimethylamine",{"v":0.9142127094883349,"d":"0.914"},{"v":0.60557663,"d":"0.606"},"",{"v":0.2669706972832541,"d":"0.267"},{"v":0.8942298,"d":"0.894"},""]
[null,"145.1332 m/z",{"v":1.091889521201769,"d":"1.09"},{"v":0.122053854,"d":"0.122"},"",{"v":0.2438039503383876,"d":"0.244"},{"v":0.80201733,"d":"0.802"},""]
[null,"Piperidine",{"v":0.8218362625879839,"d":"0.822"},{"v":0.5800556,"d":"0.580"},"",{"v":0.1198494072026481,"d":"0.120"},{"v":0.022125471,"d":"0.0221"},"*"]
[null,"Taurine",{"v":0.9095610313703663,"d":"0.910"},{"v":0.48341188,"d":"0.483"},"",{"v":0.9488086554688041,"d":"0.949"},{"v":0.9720958,"d":"0.972"},""]
[null,"Piperideine",{"v":0.9026569058458569,"d":"0.903"},{"v":0.97057515,"d":"0.971"},"",{"v":0.6847076914818535,"d":"0.685"},{"v":0.5152402,"d":"0.515"},""]
[null,"Pipecolic acid",{"v":0.8857111376115323,"d":"0.886"},{"v":0.96077526,"d":"0.961"},"",{"v":0.7978857473811836,"d":"0.798"},{"v":0.47114447,"d":"0.471"},""]
[null,"72.0813 m/z",{"v":0.9845647187691935,"d":"0.985"},{"v":0.67119414,"d":"0.671"},"",{"v":0.6068271139882003,"d":"0.607"},{"v":0.5426643,"d":"0.543"},""]
[null,"120.0801 m/z",{"v":0.9547923620835325,"d":"0.955"},{"v":0.27497298,"d":"0.275"},"",{"v":0.6470049037708537,"d":"0.647"},{"v":0.66913044,"d":"0.669"},""]
[null,"Pyrroline hydroxycarboxylic acid",{"v":1.3242241324000943,"d":"1.32"},{"v":0.1884338,"d":"0.188"},"",{"v":0.8937248947403924,"d":"0.894"},{"v":0.8711683,"d":"0.871"},""]
[null,"Betaine",{"v":0.9709087156089083,"d":"0.971"},{"v":0.5468653,"d":"0.547"},"",{"v":0.7751581193901182,"d":"0.775"},{"v":0.6593821,"d":"0.659"},""]
[null,"70.0655 m/z",{"v":1.1918971726396304,"d":"1.19"},{"v":0.9314137,"d":"0.931"},"",{"v":0.6542719546567596,"d":"0.654"},{"v":0.92197615,"d":"0.922"},""]
[null,"139.0500 m/z",{"v":0.6397102760642276,"d":"0.640"},{"v":0.28439304,"d":"0.284"},"",{"v":1.601990102375412,"d":"1.60"},{"v":0.34851632,"d":"0.349"},""]
[null,"Leucine + Isoleucine",{"v":0.7596636197269235,"d":"0.760"},{"v":0.5146303,"d":"0.515"},"",{"v":0.8848067249035005,"d":"0.885"},{"v":0.2972263,"d":"0.297"},""]
[null,"Phenylalanine",{"v":0.7242293875535467,"d":"0.724"},{"v":0.15379865,"d":"0.154"},"",{"v":0.9099660411854223,"d":"0.910"},{"v":0.82830566,"d":"0.828"},""]
[null,"Tyrosine",{"v":0.6235983746990852,"d":"0.624"},{"v":0.049156744,"d":"0.0492"},"*",{"v":0.937422691691769,"d":"0.937"},{"v":0.7317469,"d":"0.732"},""]
[null,"Histidine",{"v":0.6505362123695271,"d":"0.651"},{"v":0.23301315,"d":"0.233"},"",{"v":1.0988241772727168,"d":"1.10"},{"v":0.9944181,"d":"0.994"},""]
[null,"Proline",{"v":0.7921923723584952,"d":"0.792"},{"v":0.9705763,"d":"0.971"},"",{"v":1.290082003863322,"d":"1.29"},{"v":0.22084089,"d":"0.221"},""]
[null,"Lysine",{"v":0.6962356496188017,"d":"0.696"},{"v":0.58851576,"d":"0.589"},"",{"v":1.0931356560993004,"d":"1.09"},{"v":0.57093585,"d":"0.571"},""]
[null,"Glycine",{"v":0.714109929422078,"d":"0.714"},{"v":0.21887746,"d":"0.219"},"",{"v":0.9238717654746754,"d":"0.924"},{"v":0.5152883,"d":"0.515"},""]
[null,"Ornithine",{"v":0.8586842199005043,"d":"0.859"},{"v":0.89241654,"d":"0.892"},"",{"v":0.9486457178801183,"d":"0.949"},{"v":0.50629526,"d":"0.506"},""]
[null,"367.1977 m/z",{"v":0.7820040250449117,"d":"0.782"},{"v":0.8487436,"d":"0.849"},"",{"v":0.9328082219703205,"d":"0.933"},{"v":0.13735725,"d":"0.137"},""]
[null,"Pro-Gly-Pro or Pro-Pro-Gly",{"v":0.7872569181641087,"d":"0.787"},{"v":0.20571776,"d":"0.206"},"",{"v":0.7598300638659531,"d":"0.760"},{"v":0.9104086,"d":"0.910"},""]
[null,"173.0919 m/z",{"v":0.7327060774148336,"d":"0.733"},{"v":0.10608322,"d":"0.106"},"",{"v":0.7365034992693029,"d":"0.737"},{"v":0.69770247,"d":"0.698"},""]
[null,"Burimamide",{"v":0.7451612747540384,"d":"0.745"},{"v":0.9068754,"d":"0.907"},"",{"v":0.8162638402034234,"d":"0.816"},{"v":0.56932235,"d":"0.569"},""]
[null,"Ethanolamine",{"v":0.7671124954939865,"d":"0.767"},{"v":0.21887746,"d":"0.219"},"",{"v":0.7746138169534992,"d":"0.775"},{"v":0.77423877,"d":"0.774"},""]
[null,"gamma-Aminobutyric acid",{"v":0.9043002008400447,"d":"0.904"},{"v":0.18417767,"d":"0.184"},"",{"v":1.454385352132692,"d":"1.45"},{"v":0.09698647,"d":"0.097"},""]
[null,"Aspartic acid",{"v":0.7807044969604267,"d":"0.781"},{"v":0.35008,"d":"0.350"},"",{"v":1.0715805436522083,"d":"1.07"},{"v":0.32392108,"d":"0.324"},""]
[null,"Valine",{"v":0.8293268293093065,"d":"0.829"},{"v":0.58851576,"d":"0.589"},"",{"v":0.6729265963256367,"d":"0.673"},{"v":0.47116476,"d":"0.471"},""]
[null,"Tryptophan",{"v":0.6745841693048031,"d":"0.675"},{"v":0.17364885,"d":"0.174"},"",{"v":0.967816204660866,"d":"0.968"},{"v":0.42622867,"d":"0.426"},""]
[null,"beta-Alanine",{"v":0.6292063130851266,"d":"0.629"},{"v":0.45136404,"d":"0.451"},"",{"v":1.328116809689681,"d":"1.33"},{"v":0.5329569,"d":"0.533"},""]
[null,"Citrulline",{"v":0.6334278798431341,"d":"0.633"},{"v":0.257989,"d":"0.258"},"",{"v":1.7919764303521428,"d":"1.79"},{"v":0.55207235,"d":"0.552"},""]
[null,"Glutamic acid",{"v":0.8984349551385308,"d":"0.898"},{"v":0.55507743,"d":"0.555"},"",{"v":1.2686738374018829,"d":"1.27"},{"v":0.14757054,"d":"0.148"},""]
[null,"Threonine",{"v":0.7545855596123568,"d":"0.755"},{"v":0.094435476,"d":"0.0944"},"",{"v":1.585943338389818,"d":"1.59"},{"v":0.034024626,"d":"0.0340"},"*"]
[null,"Serine",{"v":0.6736890626982225,"d":"0.674"},{"v":0.20100299,"d":"0.201"},"",{"v":1.9094315044955283,"d":"1.91"},{"v":0.046168208,"d":"0.0462"},"*"]
[null,"Glutamine",{"v":0.8467349721865198,"d":"0.847"},{"v":0.64916545,"d":"0.649"},"",{"v":1.4096395919539757,"d":"1.41"},{"v":0.37427804,"d":"0.374"},""]
[null,"Hypoxanthine",{"v":0.9907004238551894,"d":"0.991"},{"v":0.74352795,"d":"0.744"},"",{"v":1.691450583983507,"d":"1.69"},{"v":0.88861716,"d":"0.889"},""]
[null,"Choline",{"v":0.8800617283864066,"d":"0.880"},{"v":0.8344341,"d":"0.834"},"",{"v":1.3931449965974299,"d":"1.39"},{"v":0.5243636,"d":"0.524"},""]
[null,"Carnitine",{"v":0.8016058525255004,"d":"0.802"},{"v":0.32521653,"d":"0.325"},"",{"v":1.4407733969966332,"d":"1.44"},{"v":0.6797807,"d":"0.680"},""]
[null,"118.0863 m/z, 13.42 min.",{"v":0.9410310407481496,"d":"0.941"},{"v":0.80575675,"d":"0.806"},"",{"v":2.1001597647776493,"d":"2.10"},{"v":0.6095569,"d":"0.610"},""]
[null,"Glycerophosphocholine",{"v":0.8980409062400263,"d":"0.898"},{"v":0.4226569,"d":"0.423"},"",{"v":1.580805186596448,"d":"1.58"},{"v":0.33104643,"d":"0.331"},""]
[null,"173.0285 m/z",{"v":1.0135206851486334,"d":"1.01"},{"v":0.30169517,"d":"0.302"},null,{"v":0.9739903578693194,"d":"0.974"},{"v":0.7160113,"d":"0.716"},""]
[null,"288.9691 m/z",{"v":0.6292559517460026,"d":"0.629"},{"v":0.21356556,"d":"0.214"},"",{"v":1.0624574316459388,"d":"1.06"},{"v":0.6145779,"d":"0.615"},""]
[null,"NOTE. * p < 0.05  (Steel-Dwass test). "]
[null,"   † M/F: the ratio of the average relative area between samples from male and female subjects."]
[null,"   †† The p-values were calculated by the Mann-Whitney test."]

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{"sheet":"Sheet3","index":2,"n_rows":0,"n_cols":0,"rows_kept":0,"flags":["formulas_cached_only"]}