{"text_format":"3","workbook":"xls","n_sheets":5,"sheets":["ELISA","GraphPad Results","Neutralization - 13C6","Neutralization - 2G4","Neutralization - 4G7"],"not_rendered":{"external_links":1},"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"ELISA","index":0,"n_rows":121,"n_cols":6,"rows_kept":121,"flags":["formulas_cached_only"]}
["mAb","Virus","Concentration","OD405.1","OD405.2","OD405.3"]
["4G7","Kikwit",20,2.0221,2.0072,2.0325]
["4G7","Kikwit",10,2.0683,2.0281,2.0228]
["4G7","Kikwit",5,2.0298,2.0354,2.0319]
["4G7","Kikwit",2.5,2.0071,1.9808,2.0065]
["4G7","Kikwit",1.25,2.0229,1.9962,2.0294]
["4G7","Kikwit",0.625,1.9485,1.9432,1.9869]
["4G7","Kikwit",0.3125,1.8828,1.8661,1.9724]
["4G7","Kikwit",0.15625,1.8348,1.8297,1.8331]
["4G7","Kikwit",0.078125,1.7011,1.6947,1.6239]
["4G7","Kikwit",0.0390625,1.3945,1.4429,1.3761]
["4G7","Kikwit",0.01953125,1.0385,1.0227,1.0007]
["4G7","Kikwit",0.009765625,0.6518,0.6634,0.68]
["4G7","Kikwit",0.004882813,0.3949,0.4077,0.3871]
["4G7","Kikwit",0.002441406,0.2298,0.229,0.266]
["4G7","Kikwit",0.001220703,0.1459,0.1561,0.1655]
["4G7","Kikwit",0.000610352,0.1024,0.1117,0.1086]
["4G7","Kikwit",0.000305176,0.0816,0.0796,0.0821]
["4G7","Kikwit",0.000152588,0.0663,0.0674,0.0667]
["4G7","Kikwit",{"v":7.63e-05,"d":"7.63E-05"},0.0616,0.0579,0.0619]
["4G7","Kikwit",{"v":3.81e-05,"d":"3.81E-05"},0.0564,0.057,0.0561]
["4G7","Guinea",20,2.1162,2.1364,2.1444]
["4G7","Guinea",10,2.1138,2.1141,2.119]
["4G7","Guinea",5,2.0859,2.0938,2.1247]
["4G7","Guinea",2.5,2.0873,2.0751,2.0961]
["4G7","Guinea",1.25,2.0887,2.0755,2.1059]
["4G7","Guinea",0.625,2.0953,2.0944,2.076]
["4G7","Guinea",0.3125,2.0667,2.0648,2.1045]
["4G7","Guinea",0.15625,2.0508,2.0504,2.0491]
["4G7","Guinea",0.078125,2.0288,2.0441,2.0547]
["4G7","Guinea",0.0390625,1.9179,1.9865,1.9513]
["4G7","Guinea",0.01953125,1.8038,1.7747,1.7651]
["4G7","Guinea",0.009765625,1.3365,1.3632,1.4648]
["4G7","Guinea",0.004882813,0.8783,0.8741,0.8463]
["4G7","Guinea",0.002441406,0.5225,0.5355,0.5309]
["4G7","Guinea",0.001220703,0.3186,0.3,0.3164]
["4G7","Guinea",0.000610352,0.1879,0.1897,0.1913]
["4G7","Guinea",0.000305176,0.1262,0.1259,0.135]
["4G7","Guinea",0.000152588,0.0945,0.0898,0.092]
["4G7","Guinea",{"v":7.63e-05,"d":"7.63E-05"},0.0768,0.0749,0.0737]
["4G7","Guinea",{"v":3.81e-05,"d":"3.81E-05"},0.0673,0.0661,0.0667]
["2G4","Kikwit",20,1.9739,1.9688,1.9382]
["2G4","Kikwit",10,1.9961,1.9823,1.927]
["2G4","Kikwit",5,1.962,1.9567,1.9358]
["2G4","Kikwit",2.5,1.9664,1.9414,1.9555]
["2G4","Kikwit",1.25,1.9758,1.9868,1.9416]
["2G4","Kikwit",0.625,1.9334,1.9373,1.9137]
["2G4","Kikwit",0.3125,1.8646,1.8908,1.8568]
["2G4","Kikwit",0.15625,1.7376,1.7678,1.7471]
["2G4","Kikwit",0.078125,1.6369,1.7266,1.6464]
["2G4","Kikwit",0.0390625,1.401,1.4973,1.3934]
["2G4","Kikwit",0.01953125,1.1985,1.159,1.1421]
["2G4","Kikwit",0.009765625,0.7848,0.8371,0.7977]
["2G4","Kikwit",0.004882813,0.5021,0.5347,0.5296]
["2G4","Kikwit",0.002441406,0.3139,0.3093,0.3474]
["2G4","Kikwit",0.001220703,0.1807,0.2088,0.195]
["2G4","Kikwit",0.000610352,0.1231,0.1301,0.1267]
["2G4","Kikwit",0.000305176,0.087,0.0911,0.0891]
["2G4","Kikwit",0.000152588,0.0681,0.0709,0.0719]
["2G4","Kikwit",{"v":7.63e-05,"d":"7.63E-05"},0.0588,0.0566,0.0601]
["2G4","Kikwit",{"v":3.81e-05,"d":"3.81E-05"},0.0464,0.0541,0.0547]
["2G4","Guinea",20,2.0899,2.1041,2.1151]
["2G4","Guinea",10,2.0392,2.0845,2.1037]
["2G4","Guinea",5,2.043,2.0626,2.0896]
["2G4","Guinea",2.5,2.0276,2.0463,2.0799]
["2G4","Guinea",1.25,2.0255,2.0497,2.0763]
["2G4","Guinea",0.625,2.0028,2.0563,2.0514]
["2G4","Guinea",0.3125,1.949,2.0377,2.0623]
["2G4","Guinea",0.15625,1.978,1.9997,2.0089]
["2G4","Guinea",0.078125,1.9483,1.9635,2.039]
["2G4","Guinea",0.0390625,1.795,1.9648,1.9349]
["2G4","Guinea",0.01953125,1.8663,1.8164,1.8441]
["2G4","Guinea",0.009765625,1.4819,1.5439,1.6091]
["2G4","Guinea",0.004882813,1.0318,1.1386,1.164]
["2G4","Guinea",0.002441406,0.6516,0.6672,0.6788]
["2G4","Guinea",0.001220703,0.3812,0.3893,0.4127]
["2G4","Guinea",0.000610352,0.2288,0.2534,0.2157]
["2G4","Guinea",0.000305176,0.1406,0.1379,0.1622]
["2G4","Guinea",0.000152588,0.0946,0.1003,0.1016]
["2G4","Guinea",{"v":7.63e-05,"d":"7.63E-05"},0.0757,0.0758,0.221]
["2G4","Guinea",{"v":3.81e-05,"d":"3.81E-05"},0.0634,0.0618,0.0639]
["13C6","Kikwit",20,2.0066,1.9807,1.992]
["13C6","Kikwit",10,2.002,1.9785,1.99]
["13C6","Kikwit",5,2.0087,1.9731,1.9821]
["13C6","Kikwit",2.5,2.0011,1.977,1.9521]
["13C6","Kikwit",1.25,1.983,1.9226,1.9199]
["13C6","Kikwit",0.625,1.9194,1.9027,1.8671]
["13C6","Kikwit",0.3125,1.8326,1.7522,1.7223]
["13C6","Kikwit",0.15625,1.6216,1.5849,1.6055]
["13C6","Kikwit",0.078125,1.3097,1.224,1.3862]
["13C6","Kikwit",0.0390625,0.9488,0.8923,0.8632]
["13C6","Kikwit",0.01953125,0.6972,0.6281,0.6847]
["13C6","Kikwit",0.009765625,0.4508,0.3924,0.4255]
["13C6","Kikwit",0.004882813,0.2772,0.2545,0.2454]
["13C6","Kikwit",0.002441406,0.1743,0.1622,0.1677]
["13C6","Kikwit",0.001220703,0.117,0.1133,0.1081]
["13C6","Kikwit",0.000610352,0.0856,0.0828,0.0809]
["13C6","Kikwit",0.000305176,0.0753,0.0659,0.0676]
["13C6","Kikwit",0.000152588,0.0599,0.0574,0.0582]
["13C6","Kikwit",{"v":7.63e-05,"d":"7.63E-05"},0.0551,0.0539,0.0564]
["13C6","Kikwit",{"v":3.81e-05,"d":"3.81E-05"},0.0526,0.052,0.0515]
["13C6","Guinea",20,2.0533,2.085,2.1116]
["13C6","Guinea",10,2.0553,2.0596,2.0872]
["13C6","Guinea",5,2.0362,2.0349,2.0874]
["13C6","Guinea",2.5,2.0379,2.0304,2.0672]
["13C6","Guinea",1.25,2.0081,2.0253,2.0669]
["13C6","Guinea",0.625,1.9938,2.0186,2.0366]
["13C6","Guinea",0.3125,1.9483,1.9761,2.0194]
["13C6","Guinea",0.15625,1.9156,1.8873,1.9335]
["13C6","Guinea",0.078125,1.7343,1.7752,1.7457]
["13C6","Guinea",0.0390625,1.3731,1.4047,1.4309]
["13C6","Guinea",0.01953125,0.9533,0.9836,1.0056]
["13C6","Guinea",0.009765625,0.58,0.6473,0.6188]
["13C6","Guinea",0.004882813,0.3286,0.3579,0.3553]
["13C6","Guinea",0.002441406,0.2093,0.2407,0.2319]
["13C6","Guinea",0.001220703,0.1158,0.1476,0.1452]
["13C6","Guinea",0.000610352,0.0908,0.1001,0.1013]
["13C6","Guinea",0.000305176,0.0702,0.0762,0.0803]
["13C6","Guinea",0.000152588,0.0623,0.0653,0.317]
["13C6","Guinea",{"v":7.63e-05,"d":"7.63E-05"},0.0565,0.0594,0.058]
["13C6","Guinea",{"v":3.81e-05,"d":"3.81E-05"},0.0542,0.0543,0.0542]

{"sheet":"GraphPad Results","index":1,"n_rows":36,"n_cols":7,"rows_kept":36,"flags":["formulas_cached_only"]}
[null,"13C6 - Kikwit","13C6 - Guinea C05","2G4 - Kikwit","2G4 - Guinea C05","4G7 - Kikwit","4G7 - Guinea C05"]
["log(agonist) vs. response -- Variable slope (four parameters)"]
["Best-fit values"]
["Bottom",0.05959,0.08313,0.04608,0.08866,0.06024,0.08863]
["Top",2.008,2.06,1.966,2.05,2.022,2.101]
["LogEC50",-1.348,-1.658,-1.833,-2.344,-1.699,-2.197]
["HillSlope",1.008,1.247,0.9861,1.323,1.101,1.371]
["EC50",0.04484,0.02198,0.01469,0.004528,0.02002,0.006347]
["Span",1.949,1.977,1.92,1.961,1.962,2.013]
["Std. Error"]
["Bottom",0.007927,0.009924,0.007554,0.01394,0.005895,0.008093]
["Top",0.009123,0.009377,0.006266,0.008819,0.005403,0.005665]
["LogEC50",0.01096,0.0114,0.009063,0.01273,0.007027,0.0075]
["HillSlope",0.02309,0.03597,0.0183,0.04483,0.01746,0.02839]
["Span",0.01317,0.01452,0.01072,0.01743,0.008618,0.01042]
["95% Confidence Intervals"]
["Bottom","0.04370 to 0.07548","0.06324 to 0.1030","0.03094 to 0.06121","0.06073 to 0.1166","0.04843 to 0.07206","0.07241 to 0.1049"]
["Top","1.990 to 2.027","2.042 to 2.079","1.953 to 1.978","2.032 to 2.068","2.011 to 2.033","2.090 to 2.113"]
["LogEC50","-1.370 to -1.326","-1.681 to -1.635","-1.851 to -1.815","-2.370 to -2.319","-1.713 to -1.685","-2.212 to -2.182"]
["HillSlope","0.9621 to 1.055","1.175 to 1.319","0.9494 to 1.023","1.233 to 1.413","1.066 to 1.136","1.314 to 1.428"]
["EC50","0.04263 to 0.04717","0.02085 to 0.02316","0.01409 to 0.01532","0.004269 to 0.004801","0.01938 to 0.02068","0.006131 to 0.006570"]
["Span","1.922 to 1.975","1.948 to 2.006","1.898 to 1.941","1.926 to 1.996","1.945 to 1.979","1.992 to 2.033"]
["Goodness of Fit"]
["Degrees of Freedom",56,56,56,56,56,56]
["R square",0.9986,0.998,0.9991,0.9973,0.9994,0.999]
["Absolute Sum of Squares",0.05594,0.08856,0.03545,0.1107,0.02715,0.04395]
["Sy.x",0.03161,0.03977,0.02516,0.04446,0.02202,0.02802]
["Covariance Matrix"]
["Bottom & Top",-0.189,-0.1316,-0.197,-0.129,-0.1623,-0.1187]
["Bottom & LogEC50",0.3749,0.4026,0.4778,0.5038,0.4302,0.4666]
["Bottom & HillSlope",0.4974,0.4532,0.5594,0.5194,0.5008,0.4851]
["Top & LogEC50",0.4597,0.374,0.3627,0.2771,0.3815,0.2962]
["Top & HillSlope",-0.5426,-0.4345,-0.4999,-0.3705,-0.4721,-0.3692]
["LogEC50 & HillSlope",-0.06033,0.01958,0.08209,0.1561,0.0343,0.1152]
["Number of points"]
["Analyzed",60,60,60,60,60,60]

{"sheet":"Neutralization - 13C6","index":2,"n_rows":7,"n_cols":3,"rows_kept":7,"flags":["formulas_cached_only"]}
["Concentration of 13C6 (mg/mL)","EBOV-K","EBOV-G"]
[2,60.2,48.03695]
[1,52.6,41.80138]
[0.5,30.2,22.40185]
[0.25,31,16.85912]
[0.125,17.6,9.699769]
[0.0625,0,1.616628]

{"sheet":"Neutralization - 2G4","index":3,"n_rows":7,"n_cols":3,"rows_kept":7,"flags":["formulas_cached_only"]}
["Concentration of 2G4 (mg/mL)","EBOV-K","EBOV-G"]
[2,98.82904,96.52605]
[1,97.89227,96.27792]
[0.5,98.36066,96.52605]
[0.25,95.55035,84.86353]
[0.125,88.05621,82.134]
[0.0625,73.77049,69.23077]

{"sheet":"Neutralization - 4G7","index":4,"n_rows":7,"n_cols":3,"rows_kept":7,"flags":["formulas_cached_only"]}
["Concentration of 4G7 (mg/mL)","EBOV-K","EBOV-G"]
[2,95.15789,96.52778]
[1,98.10526,96.99074]
[0.5,96.42105,86.80556]
[0.25,80,77.31481]
[0.125,69.89474,61.57407]
[0.0625,58.10526,48.84259]