{"text_format":"3","workbook":"xlsx","n_sheets":7,"sheets":["Supplementary Table 1","Supplementary Table 2","Supplementary Table 3","Supplementary Table 4","Supplementary Table 5","Supplementary Table 6","Supplementary Table 7"],"not_rendered":{"defined_names":1},"read":"whole","date_system":"1900"}

{"sheet":"Supplementary Table 1","index":0,"n_rows":12,"n_cols":6,"rows_kept":12}
["Supplementary Table 1.Demographic profile of schizophrenia samples in sQTL cohorts."]
["Dataset","Total Cases","Age(Mean+SD)","Male(%)","Female(%)","Ancestry [n (%)]"]
["CMC",211,"69.02±15.00","134（63.5%）","77（36.5%）","European:211（100%）"]
["LIBD",328,"50.12±15.13","216（65.9%）","112（34.1%）","European:169(51.5%);African Americans:156(47.6%);Asians:3(0.9%)"]
["CMC+LIBD",539,"57.28±17.64","350(64.9%)","189(35.1%)","EUR:380(70.5%);AA:156(28.9%);AS:3(0.6%)"]
[]
["Dataset: Study group or sample source."]
["Total Cases: Total number of samples in each group (n)."]
["Age (Mean±SD): Mean age with standard deviation."]
["Male (%) / Female (%): Percentage distribution of gender."]
["Ancestry [n (%)]: Ethnic/ancestral background, presented as count (n) and percentage (%)."]
["AA: African Americans; AS: Asians; EUR: European"]

{"sheet":"Supplementary Table 2","index":1,"n_rows":24830,"n_cols":17,"rows_kept":4500,"cut":true,"bounds":{"rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0}}
["Supplementary Table 2. A list of sQTL at FDR < 0.05 identified in schizophrenia samples."]
["Chr","SNP","REF","ALT","MAF","Phenotype_id","start","end","GENE","ANNOT","IMPACT","TSS_distance","BETA","SE","Pval_beta","FDR","transcript_id"]
["chr5","rs62364722","A","G",{"v":0.2653,"d":"0.265"},"5:96075822:96076970:clu_40188_NA",96075822,96076970,"CAST","upstream_gene_variant","MODIFIER",-12099,{"v":1.71207,"d":"1.712"},{"v":0.0232475,"d":"0.023"},{"v":7.85e-254,"d":"7.85E-254"},{"v":2.24e-248,"d":"2.24E-248"},"ENST00000505143;ENST00000338252;ENST00000341926;ENST00000395812;ENST00000395813;ENST00000309190;ENST00000348386;ENST00000421689;ENST00000513666;ENST00000508830;ENST00000504465;ENST00000508608;ENST00000510756;ENST00000515063;ENST00000675479;ENST00000718093;ENST00000675107;ENST00000511097;ENST00000674702;ENST00000675179;ENST00000674984;ENST00000512620;ENST00000675663;ENST00000675033;ENST00000675267;ENST00000675266;ENST00000675614;ENST00000675858;ENST00000511049;ENST00000510156;ENST00000509903;ENST00000511782;ENST00000674587;ENST00000502568"]
["chr14","rs2297616","A","G",{"v":0.1827,"d":"0.183"},"14:20813285:20813553:clu_19034_NA",20813285,20813553,"PARP2","splice_region_variant&intron_variant","LOW",3,{"v":1.78037,"d":"1.780"},{"v":0.026321,"d":"0.026"},{"v":1.37e-236,"d":"1.37E-236"},{"v":1.95e-231,"d":"1.95E-231"},"ENST00000250416;ENST00000529465;ENST00000429687;ENST00000527915;ENST00000528210"]
["chr14","rs4900071","T","C",{"v":0.2617,"d":"0.262"},"14:91636530:91639633:clu_21172_NA",91636530,91639633,"C14orf159","3_prime_UTR_variant","MODIFIER",-136,{"v":1.78279,"d":"1.783"},{"v":0.031586,"d":"0.032"},{"v":8.16e-224,"d":"8.16E-224"},{"v":7.75e-219,"d":"7.75E-219"},"ENST00000256324;ENST00000518868;ENST00000412671;ENST00000428926;ENST00000517306;ENST00000517518;ENST00000518649;ENST00000519994;ENST00000521077;ENST00000519950;ENST00000521334;ENST00000520328;ENST00000522170;ENST00000522322;ENST00000523461;ENST00000523771;ENST00000523816;ENST00000523837;ENST00000523894;ENST00000525393"]
["chr14","rs2297616","A","G",{"v":0.1827,"d":"0.183"},"14:20813246:20813553:clu_19034_NA",20813246,20813553,"PARP2","splice_region_variant&intron_variant","LOW",42,{"v":-2.18598,"d":"-2.186"},{"v":0.0342127,"d":"0.034"},{"v":3.01e-216,"d":"3.01E-216"},2.15E-211,"ENST00000250416;ENST00000529465;ENST00000429687;ENST00000527915;ENST00000528210"]
["chr1","rs3762374","T","C",{"v":0.2635,"d":"0.264"},"1:111680208:111682660:clu_11056_NA",111680208,111682660,"CEPT1;DRAM2","splice_region_variant&intron_variant","LOW",1909,{"v":1.59018,"d":"1.590"},{"v":0.0330211,"d":"0.033"},7.02E-186,{"v":4e-181,"d":"4.00E-181"},"ENST00000484310;ENST00000286692;ENST00000539140;ENST00000496430;ENST00000480600;ENST00000490780;ENST00000463682;ENST00000700750;ENST00000498239;ENST00000545121;ENST00000480324;ENST00000476865"]
["chr19","rs9749084","G","A",{"v":0.1911,"d":"0.191"},"19:57005711:57006417:clu_47484_NA",57005711,57006417,"-","upstream_gene_variant","MODIFIER",-9975,{"v":-2.17674,"d":"-2.177"},{"v":0.0461368,"d":"0.046"},{"v":2.59e-183,"d":"2.59E-183"},1.23E-178,"ENST00000654200;ENST00000585445;ENST00000586091;ENST00000586822;ENST00000594783;ENST00000601875;ENST00000588158;ENST00000592146;ENST00000664785;ENST00000661902;ENST00000665045;ENST00000809481;ENST00000654382;ENST00000809482;ENST00000809483;ENST00000667367;ENST00000669162;ENST00000670294;ENST00000685306;ENST00000809478;ENST00000691191;ENST00000693493;ENST00000809477;ENST00000809479;ENST00000809480;ENST00000809366;ENST00000809372;ENST00000809371;ENST00000809369;ENST00000809368;ENST00000809367;ENST00000809370"]
["chr17","rs4925036","G","A",{"v":0.4768,"d":"0.477"},"17:19575269:19578809:clu_68046_NA",19575269,19578809,"ALDH3A2","upstream_gene_variant","MODIFIER",-21611,{"v":-1.60262,"d":"-1.603"},{"v":0.0341984,"d":"0.034"},{"v":4.43e-177,"d":"4.43E-177"},{"v":1.8e-172,"d":"1.80E-172"},"ENST00000581518;ENST00000176643;ENST00000339618;ENST00000395575;ENST00000472059;ENST00000673472;ENST00000573505;ENST00000672608;ENST00000476965;ENST00000574078;ENST00000673064;ENST00000673516;ENST00000672591;ENST00000571163;ENST00000573947;ENST00000575384;ENST00000573565;ENST00000574597;ENST00000579855;ENST00000673136;ENST00000672465;ENST00000631291;ENST00000672357;ENST00000672564;ENST00000582991;ENST00000671878;ENST00000672059;ENST00000672487;ENST00000630662;ENST00000672567;ENST00000672709"]
["chr19","rs3852885","T","C",{"v":0.3383,"d":"0.338"},"19:54704829:54705028:clu_47236_NA",54704829,54705028,"RPS9","upstream_gene_variant","MODIFIER",2732,{"v":1.39389,"d":"1.394"},{"v":0.0309483,"d":"0.031"},{"v":3.58e-173,"d":"3.58E-173"},1.28E-168,"ENST00000484121;ENST00000626547;ENST00000302907;ENST00000448962;ENST00000436445;ENST00000391752;ENST00000402367;ENST00000445961;ENST00000391751;ENST00000495002;ENST00000391753;ENST00000460761;ENST00000441429"]
["chr2","rs2276611","A","G",{"v":0.1515,"d":"0.152"},"2:170441007:170460152:clu_4395_NA",170441007,170460152,"-","splice_donor_variant&intron_variant","HIGH",-7,{"v":1.85386,"d":"1.854"},{"v":0.0382001,"d":"0.038"},{"v":4.53e-166,"d":"4.53E-166"},{"v":1.44e-161,"d":"1.44E-161"},"ENST00000825053;ENST00000414307;ENST00000433207;ENST00000677750;ENST00000677392;ENST00000676508;ENST00000260970;ENST00000409714;ENST00000530152;ENST00000676557;ENST00000448752;ENST00000462903;ENST00000676756;ENST00000678088;ENST00000679107;ENST00000678499;ENST00000678638;ENST00000678695;ENST00000678721;ENST00000679324"]
["chr5","rs71630748","G","A",{"v":0.2644,"d":"0.264"},"5:96076487:96076970:clu_40188_NA",96076487,96076970,"CAST","upstream_gene_variant","MODIFIER",-15896,{"v":-1.73431,"d":"-1.734"},{"v":0.0410013,"d":"0.041"},{"v":3.89e-158,"d":"3.89E-158"},1.11E-153,"ENST00000338252;ENST00000341926;ENST00000395812;ENST00000395813;ENST00000309190;ENST00000348386;ENST00000421689;ENST00000513666;ENST00000508830;ENST00000504465;ENST00000508608;ENST00000510756;ENST00000515063;ENST00000675479;ENST00000718093;ENST00000675107;ENST00000511097;ENST00000674702;ENST00000675179;ENST00000674984;ENST00000512620;ENST00000675663;ENST00000675033;ENST00000675267;ENST00000675266;ENST00000675614;ENST00000675858;ENST00000511049;ENST00000510156;ENST00000509903;ENST00000511782;ENST00000674587;ENST00000502568"]
["chr14","rs4900071","T","C",{"v":0.2617,"d":"0.262"},"14:91636545:91639633:clu_21172_NA",91636545,91639633,"C14orf159","3_prime_UTR_variant","MODIFIER",-151,{"v":-1.80378,"d":"-1.804"},{"v":0.0423745,"d":"0.042"},{"v":6.48e-158,"d":"6.48E-158"},{"v":1.68e-153,"d":"1.68E-153"},"ENST00000256324;ENST00000518868;ENST00000412671;ENST00000428926;ENST00000517306;ENST00000517518;ENST00000518649;ENST00000519994;ENST00000521077;ENST00000519950;ENST00000521334;ENST00000520328;ENST00000522170;ENST00000522322;ENST00000523461;ENST00000523771;ENST00000523816;ENST00000523837;ENST00000523894;ENST00000525393"]
["chr1","rs479094","T","C",{"v":0.4438,"d":"0.444"},"1:179853904:179858445:clu_13232_NA",179853904,179858445,"TOR1AIP1","upstream_gene_variant","MODIFIER",-11798,{"v":1.71417,"d":"1.714"},{"v":0.0415102,"d":"0.042"},{"v":2.51e-157,"d":"2.51E-157"},{"v":5.96e-153,"d":"5.96E-153"},"ENST00000528443;ENST00000606911;ENST00000271583;ENST00000435319;ENST00000531630;ENST00000527391;ENST00000529091;ENST00000527867;ENST00000474875;ENST00000531726;ENST00000524653"]
["chr2","rs1177306","A","G",{"v":0.4145,"d":"0.415"},"2:61385147:61389977:clu_1700_NA",61385147,61389977,"C2orf74;KIAA1841","upstream_gene_variant","MODIFIER",2688,{"v":-1.45931,"d":"-1.459"},{"v":0.0352377,"d":"0.035"},1.04E-154,2.28E-150,"ENST00000462959;ENST00000715767;ENST00000733743;ENST00000733741;ENST00000733744;ENST00000605902;ENST00000606876;ENST00000733742;ENST00000607743;ENST00000733745;ENST00000733746;ENST00000426997;ENST00000464909;ENST00000489686;ENST00000398622;ENST00000432605;ENST00000488469"]
["chr19","rs9749084","G","A",{"v":0.1911,"d":"0.191"},"19:57005711:57006416:clu_47484_NA",57005711,57006416,"-","upstream_gene_variant","MODIFIER",-9975,{"v":1.76525,"d":"1.765"},{"v":0.0396219,"d":"0.040"},{"v":2.2e-154,"d":"2.20E-154"},{"v":4.47999999999999e-150,"d":"4.48E-150"},"ENST00000654200;ENST00000585445;ENST00000586091;ENST00000586822;ENST00000594783;ENST00000601875;ENST00000588158;ENST00000592146;ENST00000664785;ENST00000661902;ENST00000665045;ENST00000809481;ENST00000654382;ENST00000809482;ENST00000809483;ENST00000667367;ENST00000669162;ENST00000670294;ENST00000685306;ENST00000809478;ENST00000691191;ENST00000693493;ENST00000809477;ENST00000809479;ENST00000809480;ENST00000809366;ENST00000809372;ENST00000809371;ENST00000809369;ENST00000809368;ENST00000809367;ENST00000809370"]
["chr19","rs2304243","G","C",{"v":0.4291,"d":"0.429"},"19:41938313:41939442:clu_45847_NA",41938313,41939442,"-","upstream_gene_variant","MODIFIER",4394,{"v":-1.40584,"d":"-1.406"},{"v":0.0367715,"d":"0.037"},{"v":4.32e-148,"d":"4.32E-148"},{"v":8.21e-144,"d":"8.21E-144"},"ENST00000438807;ENST00000221943;ENST00000589503;ENST00000592922;ENST00000594660;ENST00000301183;ENST00000589970;ENST00000417807;ENST00000590641;ENST00000594339;ENST00000597457;ENST00000595425;ENST00000589102;ENST00000595407"]
["chr10","rs9340156","T","C",{"v":0.2069,"d":"0.207"},"10:38654557:38658881:clu_16192_NA",38654557,38658881,"-","intron_variant","MODIFIER",-46907,{"v":-2.08314,"d":"-2.083"},{"v":0.0496768,"d":"0.050"},{"v":1.46e-147,"d":"1.46E-147"},{"v":2.6e-143,"d":"2.60E-143"},"ENST00000494540;ENST00000812332;ENST00000812333;ENST00000471365"]
["chr5","rs62364722","A","G",{"v":0.2653,"d":"0.265"},"5:96075822:96076449:clu_40188_NA",96075822,96076449,"-","upstream_gene_variant","MODIFIER",-12099,{"v":-1.75626,"d":"-1.756"},{"v":0.0407506,"d":"0.041"},{"v":1.20999999999999e-146,"d":"1.21E-146"},2.03E-142,"ENST00000505143;ENST00000338252;ENST00000341926;ENST00000395812;ENST00000395813;ENST00000309190;ENST00000348386;ENST00000421689;ENST00000513666;ENST00000508830;ENST00000504465;ENST00000508608;ENST00000510756;ENST00000515063;ENST00000675479;ENST00000718093;ENST00000675107;ENST00000511097;ENST00000674702;ENST00000675179;ENST00000674984;ENST00000512620;ENST00000675663;ENST00000675033;ENST00000675267;ENST00000675266;ENST00000675614;ENST00000675858;ENST00000511049;ENST00000510156;ENST00000509903;ENST00000511782;ENST00000674587"]
["chr1","rs479094","T","C",{"v":0.4438,"d":"0.444"},"1:179853904:179858448:clu_13232_NA",179853904,179858448,"TOR1AIP1","upstream_gene_variant","MODIFIER",-11798,{"v":-1.63266,"d":"-1.633"},{"v":0.0417979,"d":"0.042"},1.59E-145,{"v":2.52e-141,"d":"2.52E-141"},"ENST00000528443;ENST00000606911;ENST00000271583;ENST00000435319;ENST00000531630;ENST00000527391;ENST00000529091;ENST00000527867;ENST00000474875;ENST00000531726;ENST00000524653"]
["chr8","rs7004974","G","T",{"v":0.2063,"d":"0.206"},"8:124153141:124156957:clu_86287_NA",124153141,124156957,"TBC1D31","intron_variant","MODIFIER",1042,{"v":1.63875,"d":"1.639"},{"v":0.0445934,"d":"0.045"},{"v":1.16e-143,"d":"1.16E-143"},{"v":1.74e-139,"d":"1.74E-139"},"ENST00000287380;ENST00000327098;ENST00000522420;ENST00000521676;ENST00000524307;ENST00000518805;ENST00000518866"]
["chr5","rs2891980","C","T",0.224,"5:82554496:82648950:clu_39943_NA",82554496,82648950,"XRCC4","intron_variant","MODIFIER",88166,{"v":1.77212,"d":"1.772"},{"v":0.0447902,"d":"0.045"},{"v":8.29e-143,"d":"8.29E-143"},1.18E-138,"ENST00000282268;ENST00000338635;ENST00000396027;ENST00000542685;ENST00000511817;ENST00000509268;ENST00000513804"]
["chr20","rs62200158","T","C",0.171,"20:61545758:61557791:clu_83368_NA",61545758,61557791,"DIDO1","upstream_gene_variant","MODIFIER",12147,{"v":1.62273,"d":"1.623"},{"v":0.0380061,"d":"0.038"},{"v":1.30999999999999E-140,"d":"1.31E-140"},1.78E-136,"ENST00000266070;ENST00000395343;ENST00000395340;ENST00000370371;ENST00000370368;ENST00000354665;ENST00000370366"]
["chr2","rs1177306","A","G",{"v":0.4145,"d":"0.415"},"2:61372331:61384997:clu_1700_NA",61372331,61384997,"C2orf74;KIAA1841","upstream_gene_variant","MODIFIER",15504,{"v":-1.37324,"d":"-1.373"},{"v":0.0372388,"d":"0.037"},{"v":4.56e-140,"d":"4.56E-140"},{"v":5.91e-136,"d":"5.91E-136"},"ENST00000462959;ENST00000715767;ENST00000733743;ENST00000733741;ENST00000733744;ENST00000605902;ENST00000606876;ENST00000733742;ENST00000607743;ENST00000733745;ENST00000426997;ENST00000464909;ENST00000489686;ENST00000398622"]
["chr8","rs4510829","A","G",{"v":0.2523,"d":"0.252"},"8:100904275:100905867:clu_85901_NA",100904275,100905867,"COX6C","upstream_gene_variant","MODIFIER",-13066,{"v":-1.5017,"d":"-1.502"},{"v":0.0412295,"d":"0.041"},{"v":7.76e-135,"d":"7.76E-135"},{"v":9.62e-131,"d":"9.62E-131"},"ENST00000522934;ENST00000520517;ENST00000520468;ENST00000297564;ENST00000520271;ENST00000517682;ENST00000524245;ENST00000522940;ENST00000518171;ENST00000523016;ENST00000662759"]
["chr19","rs16996320","T","C",{"v":0.1506,"d":"0.151"},"19:19910259:19916840:clu_44703_NA",19910259,19916840,"-","upstream_gene_variant","MODIFIER",-22968,{"v":1.51973,"d":"1.520"},{"v":0.0407178,"d":"0.041"},{"v":3.5E-133,"d":"3.50E-133"},{"v":4.16e-129,"d":"4.16E-129"},"ENST00000590274;ENST00000715984;ENST00000715985;ENST00000591639;ENST00000587461;ENST00000586260;ENST00000590766;ENST00000540806;ENST00000450683;ENST00000590319;ENST00000587452;ENST00000545006;ENST00000589657;ENST00000591884;ENST00000736570;ENST00000736561;ENST00000736562;ENST00000736568;ENST00000687800;ENST00000702258;ENST00000736560;ENST00000736565;ENST00000736566;ENST00000736564;ENST00000736563;ENST00000736567;ENST00000736569;ENST00000736576;ENST00000736573;ENST00000736581;ENST00000736571;ENST00000736574;ENST00000736578;ENST00000736575;ENST00000736577;ENST00000736580;ENST00000736572;ENST00000736579;ENST00000736582;ENST00000736584;ENST00000736583;ENST00000736585"]
["chr7","rs10241185","T","G",{"v":0.1447,"d":"0.145"},"7:128263835:128266349:clu_90451_NA",128263835,128266349,"-","intron_variant","MODIFIER",-22934,{"v":1.65146,"d":"1.651"},{"v":0.0368581,"d":"0.037"},{"v":4.41e-130,"d":"4.41E-130"},{"v":5.03e-126,"d":"5.03E-126"},"ENST00000720477;ENST00000720480;ENST00000720478;ENST00000720479;ENST00000605862;ENST00000720481;ENST00000720492;ENST00000588755"]
["chr2","rs2290911","G","A",{"v":0.2931,"d":"0.293"},"2:219001:229966:clu_5_NA",219001,229966,"SH3YL1","splice_region_variant&non_coding_transcript_exon_variant","LOW",5917,{"v":1.6085,"d":"1.609"},{"v":0.0453642,"d":"0.045"},2.16E-127,{"v":2.37e-123,"d":"2.37E-123"},"ENST00000403712;ENST00000356150;ENST00000463865;ENST00000403657;ENST00000405430;ENST00000403658;ENST00000468321;ENST00000451005;ENST00000431160;ENST00000472012;ENST00000473104;ENST00000479739;ENST00000626873"]
["chr1","rs12744791","T","C",{"v":0.1341,"d":"0.134"},"1:233086490:233092093:clu_14790_NA",233086490,233092093,"NTPCR","upstream_gene_variant","MODIFIER",3237,{"v":1.57557,"d":"1.576"},{"v":0.0378366,"d":"0.038"},{"v":1.28999999999999E-126,"d":"1.29E-126"},1.36E-122,"ENST00000494689;ENST00000366628;ENST00000490807;ENST00000496662;ENST00000366627;ENST00000479125;ENST00000487953"]
["chr20","rs6075340","A","G",{"v":0.3449,"d":"0.345"},"20:1896101:1902041:clu_81363_NA",1896101,1902041,"SIRPA","intron_variant","MODIFIER",-1767,{"v":-1.41019,"d":"-1.410"},{"v":0.0396726,"d":"0.040"},{"v":1.7E-126,"d":"1.70E-126"},{"v":1.73e-122,"d":"1.73E-122"},"ENST00000400068;ENST00000622179;ENST00000356025;ENST00000358771"]
["chr10","rs12220267","T","C",{"v":0.2783,"d":"0.278"},"10:105154151:105156166:clu_18034_NA",105154151,105156166,"USMG5","upstream_gene_variant","MODIFIER",-78440,{"v":1.34128,"d":"1.341"},{"v":0.0371271,"d":"0.037"},{"v":6.91e-126,"d":"6.91E-126"},{"v":6.79e-122,"d":"6.79E-122"},"ENST00000369825;ENST00000369811;ENST00000309579;ENST00000337003;ENST00000369815;ENST00000408840"]
["chr14","rs112997158","T","C",{"v":0.09756,"d":"0.098"},"14:104380970:104381403:clu_21776_NA",104380970,104381403,"C14orf2","upstream_gene_variant","MODIFIER",-46,{"v":1.85996,"d":"1.860"},{"v":0.0430015,"d":"0.043"},{"v":5.22e-124,"d":"5.22E-124"},{"v":4.96e-120,"d":"4.96E-120"},"ENST00000286953;ENST00000554880;ENST00000555030;ENST00000414262;ENST00000553430;ENST00000557040;ENST00000553449;ENST00000554089;ENST00000554713;ENST00000557260;ENST00000554528"]
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["chr15","rs10152371","G","A",{"v":0.3905,"d":"0.391"},"15:41102955:41105536:clu_52635_NA",41102955,41105536,"ZFYVE19","upstream_gene_variant","MODIFIER",337,{"v":-1.21325,"d":"-1.213"},{"v":0.0486594,"d":"0.049"},4.62E-85,1.23E-81,"ENST00000570108;ENST00000564258;ENST00000355341;ENST00000336455;ENST00000299173;ENST00000566407;ENST00000561617;ENST00000569057;ENST00000561768;ENST00000560078;ENST00000570162"]
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["chr22","rs136564","C","T",{"v":0.1132,"d":"0.113"},"22:45723944:45726484:clu_23670_NA",45723944,45726484,"FAM118A","intron_variant","MODIFIER",40929,{"v":-1.42929,"d":"-1.429"},{"v":0.1005,"d":"0.101"},{"v":9.28e-35,"d":"9.28E-35"},{"v":3.34e-32,"d":"3.34E-32"},"ENST00000216214;ENST00000441876;ENST00000405673;ENST00000477714;ENST00000476478;ENST00000459849;ENST00000476754;ENST00000487732"]
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["chr19","rs1991460","A","C",{"v":0.3836,"d":"0.384"},"19:40839836:40842017:clu_45738_NA",40839836,40842017,"C19orf47","upstream_gene_variant","MODIFIER",-6768,{"v":-0.979397,"d":"-0.979"},{"v":0.0628383,"d":"0.063"},{"v":1.05999999999999E-34,"d":"1.06E-34"},{"v":3.8e-32,"d":"3.80E-32"},"ENST00000683109;ENST00000582783;ENST00000392035;ENST00000357884;ENST00000582006;ENST00000580606;ENST00000580977"]
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["chr6","rs1745870","G","C",{"v":0.3368,"d":"0.337"},"6:84417676:84418763:clu_74284_NA",84417676,84418763,"SNAP91","upstream_gene_variant","MODIFIER",3067,{"v":-0.791877,"d":"-0.792"},{"v":0.0561037,"d":"0.056"},{"v":1.27e-34,"d":"1.27E-34"},{"v":4.53e-32,"d":"4.53E-32"},"ENST00000369694;ENST00000195649;ENST00000439399;ENST00000521743;ENST00000520302;ENST00000518312;ENST00000520213;ENST00000519825;ENST00000521616;ENST00000521485;ENST00000369690;ENST00000518309;ENST00000519779;ENST00000522248;ENST00000523484;ENST00000523585;ENST00000523199"]
["chr10","rs568526","C","T",0.461,"10:106037874:106057336:clu_18104_NA",106037874,106057336,"GSTO2","upstream_gene_variant","MODIFIER",-4436,{"v":-0.871199,"d":"-0.871"},{"v":0.0636308,"d":"0.064"},1.33E-34,{"v":4.73e-32,"d":"4.73E-32"},"ENST00000450629;ENST00000338595;ENST00000473401;ENST00000477078;ENST00000369707;ENST00000467629;ENST00000498052"]
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["chr2","rs10929581","T","C",{"v":0.3117,"d":"0.312"},"2:9552534:9558755:clu_222_NA",9552534,9558755,"ITGB1BP1","upstream_gene_variant","MODIFIER",-156,{"v":0.84734,"d":"0.847"},{"v":0.0589842,"d":"0.059"},1.12E-33,3.77E-31,"ENST00000355346;ENST00000238091;ENST00000483795;ENST00000488451;ENST00000460001;ENST00000464228;ENST00000465527;ENST00000359712;ENST00000360635;ENST00000456913;ENST00000463190;ENST00000467606;ENST00000482798;ENST00000484735;ENST00000490426;ENST00000492079;ENST00000494563;ENST00000497031;ENST00000497105"]
["chr9","rs7258","T","C",{"v":0.2198,"d":"0.220"},"9:131193582:131197932:clu_31920_NA",131193582,131197932,"CERCAM","downstream_gene_variant","MODIFIER",3112,{"v":0.878082,"d":"0.878"},{"v":0.0563903,"d":"0.056"},1.21E-33,{"v":4.07e-31,"d":"4.07E-31"},"ENST00000372842;ENST00000372838;ENST00000463535;ENST00000487001;ENST00000472858;ENST00000610052"]
["chr13","rs139046616","A","ATAG",{"v":0.4371,"d":"0.437"},"13:76104402:76123459:clu_80559_NA",76104402,76123459,"COMMD6","upstream_gene_variant","MODIFIER",21765,{"v":1.0434,"d":"1.043"},{"v":0.0721257,"d":"0.072"},1.31E-33,{"v":4.4e-31,"d":"4.40E-31"},"ENST00000682242;ENST00000377615;ENST00000483290;ENST00000377619;ENST00000486516;ENST00000355801;ENST00000497707;ENST00000377612;ENST00000460675;ENST00000464050;ENST00000477377;ENST00000471682;ENST00000626103"]
["chr14","rs748762","C","T",{"v":0.4674,"d":"0.467"},"14:94564024:94567085:clu_21354_NA",94564024,94567085,"IFI27L1","intron_variant","MODIFIER",1125,{"v":0.821791,"d":"0.822"},{"v":0.058473,"d":"0.058"},{"v":1.81e-33,"d":"1.81E-33"},{"v":6.08e-31,"d":"6.08E-31"},"ENST00000553350;ENST00000555523;ENST00000557600;ENST00000393115;ENST00000554166;ENST00000556381;ENST00000553664;ENST00000555341;ENST00000557218;ENST00000554544;ENST00000557066;ENST00000554562"]
["chr20","rs59684388","A","G",{"v":0.1051,"d":"0.105"},"20:62033146:62033437:clu_83444_NA",62033146,62033437,"-","3_prime_UTR_variant","MODIFIER",440,{"v":-1.18906,"d":"-1.189"},{"v":0.0824223,"d":"0.082"},{"v":1.84e-33,"d":"1.84E-33"},6.17E-31,"ENST00000627221;ENST00000359125;ENST00000370224;ENST00000629241;ENST00000625514;ENST00000626839;ENST00000629676;ENST00000706989;ENST00000637632"]
["chr22","rs6007864","C","T",{"v":0.3058,"d":"0.306"},"22:48872223:48884192:clu_23775_NA",48872223,48884192,"-","upstream_gene_variant","MODIFIER",10857,{"v":-0.733648,"d":"-0.734"},{"v":0.0517329,"d":"0.052"},1.88E-33,{"v":6.29999999999999e-31,"d":"6.30E-31"},"ENST00000667577;ENST00000666116;ENST00000663363;ENST00000659917;ENST00000669310;ENST00000662490;ENST00000748278;ENST00000748277;ENST00000748276;ENST00000748464;ENST00000748465"]
["chr1","rs12722932","C","T",{"v":0.2432,"d":"0.243"},"1:81880036:81910706:clu_10312_NA",81880036,81910706,"LPHN2","intron_variant","MODIFIER",5343,{"v":-0.947964,"d":"-0.948"},{"v":0.0689302,"d":"0.069"},{"v":2.02e-33,"d":"2.02E-33"},6.76E-31,"ENST00000370721;ENST00000370723;ENST00000370725;ENST00000370727;ENST00000370728;ENST00000370730;ENST00000674378;ENST00000469377;ENST00000473719;ENST00000492666;ENST00000674386;ENST00000674458;ENST00000444546"]
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["chr19","rs2288916","C","G",{"v":0.3973,"d":"0.397"},"19:46971834:46972919:clu_46309_NA",46971834,46972919,"PNMAL1","intron_variant","MODIFIER",1132,{"v":-0.8301,"d":"-0.830"},{"v":0.0592561,"d":"0.059"},{"v":2.5e-33,"d":"2.50E-33"},{"v":8.29e-31,"d":"8.29E-31"},"ENST00000438932;ENST00000313683;ENST00000602246"]
["chr17","rs11546632","C","T",{"v":0.1443,"d":"0.144"},"17:79649705:79650043:clu_71404_NA",79649705,79650043,"ARL16","3_prime_UTR_variant","MODIFIER",-14893,{"v":1.06019,"d":"1.060"},{"v":0.0755069,"d":"0.076"},{"v":2.52e-33,"d":"2.52E-33"},{"v":8.34e-31,"d":"8.34E-31"},"ENST00000570561;ENST00000577142;ENST00000622299;ENST00000573392;ENST00000571082;ENST00000570910;ENST00000574938;ENST00000576135;ENST00000573569;ENST00000573715;ENST00000576914;ENST00000572704;ENST00000572937"]
["chr21","rs368011189","T","TGGGCAGGGAG",{"v":0.4259,"d":"0.426"},"21:47613179:47613422:clu_62886_NA",47613179,47613422,"AP001468.1;LSS","upstream_gene_variant","MODIFIER",18783,{"v":0.733866,"d":"0.734"},{"v":0.0506055,"d":"0.051"},{"v":2.54e-33,"d":"2.54E-33"},{"v":8.4e-31,"d":"8.40E-31"},"ENST00000356396;ENST00000491729;ENST00000397728;ENST00000419093;ENST00000457828;ENST00000474319;ENST00000522411"]
["chr10","rs4745814","T","A",{"v":0.3567,"d":"0.357"},"10:77818541:78084159:clu_17077_NA",77818541,78084159,"C10orf11","intron_variant","MODIFIER",385834,{"v":0.787231,"d":"0.787"},{"v":0.0563416,"d":"0.056"},{"v":3.21e-33,"d":"3.21E-33"},1.06E-30,"ENST00000611255;ENST00000593699;ENST00000372499;ENST00000496424;ENST00000488655;ENST00000598708;ENST00000408305;ENST00000491887;ENST00000365084;ENST00000622980;ENST00000801795"]
["chr7","rs38497","A","G",0.367,"7:30617707:30618622:clu_88009_NA",30617707,30618622,"-","upstream_gene_variant","MODIFIER",8861,-1.169,{"v":0.0842649,"d":"0.084"},{"v":3.3e-33,"d":"3.30E-33"},1.09E-30,"ENST00000426529;ENST00000580440;ENST00000454922;ENST00000583664;ENST00000578994;ENST00000579174;ENST00000581665;ENST00000581794;ENST00000582733;ENST00000584023;ENST00000582549;ENST00000584199;ENST00000656284;ENST00000667338;ENST00000785590;ENST00000657049;ENST00000660767;ENST00000785589;ENST00000667137;ENST00000785588;ENST00000584372;ENST00000663944;ENST00000667129;ENST00000689508;ENST00000785592;ENST00000785591;ENST00000785593;ENST00000785595;ENST00000785596;ENST00000785594;ENST00000785597"]
["chr19","rs1722541","G","A",{"v":0.04229,"d":"0.042"},"19:51471847:51472746:clu_46950_NA",51471847,51472746,"KLK6","upstream_gene_variant","MODIFIER",3089,-1.966,{"v":0.0903902,"d":"0.090"},{"v":3.32e-33,"d":"3.32E-33"},1.09E-30,"ENST00000376851;ENST00000310157;ENST00000391808;ENST00000597379;ENST00000599690;ENST00000599881;ENST00000671133;ENST00000594512"]
["chr22","rs6007864","C","T",{"v":0.3058,"d":"0.306"},"22:48872223:48884494:clu_23775_NA",48872223,48884494,"-","upstream_gene_variant","MODIFIER",10857,{"v":-0.767672,"d":"-0.768"},{"v":0.0519043,"d":"0.052"},3.44E-33,{"v":1.12999999999999e-30,"d":"1.13E-30"},"ENST00000667577;ENST00000666116;ENST00000663363;ENST00000659917;ENST00000669310;ENST00000662490;ENST00000748278;ENST00000748277;ENST00000748276;ENST00000748464;ENST00000748465"]
["chr12","rs11063369","G","A",{"v":0.4019,"d":"0.402"},"12:4923944:4948463:clu_57127_NA",4923944,4948463,"KCNA6;GALNT8","intron_variant","MODIFIER",34207,{"v":-1.14983,"d":"-1.150"},{"v":0.0829633,"d":"0.083"},{"v":3.46e-33,"d":"3.46E-33"},1.14E-30,"ENST00000542998;ENST00000541339;ENST00000664363;ENST00000662877;ENST00000512511"]
["chr9","rs4742953","C","G",{"v":0.2649,"d":"0.265"},"9:108320446:108337226:clu_31165_NA",108320446,108337226,"FKTN","5_prime_UTR_variant","MODIFIER",15511,{"v":0.842815,"d":"0.843"},{"v":0.0579626,"d":"0.058"},{"v":3.63e-33,"d":"3.63E-33"},1.19E-30,"ENST00000421614;ENST00000815593;ENST00000815592;ENST00000223528;ENST00000357998;ENST00000448551;ENST00000602661;ENST00000479846;ENST00000490134;ENST00000675443;ENST00000674563;ENST00000675232;ENST00000675668;ENST00000675695;ENST00000675736;ENST00000676192"]
["chr20","rs59684388","A","G",{"v":0.1051,"d":"0.105"},"20:62033436:62033612:clu_83444_NA",62033436,62033612,"-","3_prime_UTR_variant","MODIFIER",150,{"v":-1.10218,"d":"-1.102"},{"v":0.0776422,"d":"0.078"},3.78E-33,1.24E-30,"ENST00000627221;ENST00000359125;ENST00000370224;ENST00000629241;ENST00000625514;ENST00000626839;ENST00000629676;ENST00000706989;ENST00000637632"]
["chr17","rs1468512","T","C",{"v":0.1696,"d":"0.170"},"17:67218838:67221466:clu_70495_NA",67218838,67221466,"-","splice_donor_variant&intron_variant","HIGH",929,{"v":1.16432,"d":"1.164"},{"v":0.0858727,"d":"0.086"},{"v":4.05e-33,"d":"4.05E-33"},{"v":1.32999999999999e-30,"d":"1.33E-30"},"ENST00000690296;ENST00000269081;ENST00000522406;ENST00000518929;ENST00000523419;ENST00000523512;ENST00000521526"]
["chr7","rs141352106","A","AAC",{"v":0.1222,"d":"0.122"},"7:102309451:102316206:clu_89974_NA",102309451,102316206,"-","upstream_gene_variant","MODIFIER",23219,{"v":-1.63035,"d":"-1.630"},{"v":0.118583,"d":"0.119"},4.47E-33,{"v":1.45999999999999e-30,"d":"1.46E-30"},"ENST00000639209;ENST00000476151;ENST00000358438;ENST00000333432"]
["chr1","rs12146148","T","C",{"v":0.2597,"d":"0.260"},"1:89458781:89533508:clu_10498_NA",89458781,89533508,"GBP3;GBP1","upstream_gene_variant","MODIFIER",13110,{"v":0.892347,"d":"0.892"},{"v":0.0594077,"d":"0.059"},{"v":4.97e-33,"d":"4.97E-33"},1.62E-30,"ENST00000824612;ENST00000824613;ENST00000824611;ENST00000824610;ENST00000850557;ENST00000370482;ENST00000489444;ENST00000370481;ENST00000493594;ENST00000235878;ENST00000461384;ENST00000445969;ENST00000564665;ENST00000475853;ENST00000568006;ENST00000564037;ENST00000365515;ENST00000459831;ENST00000370473;ENST00000495131;ENST00000484970;ENST00000468959;ENST00000479889;ENST00000681280;ENST00000493139;ENST00000469194"]
["chr1","rs34815285","T","C",{"v":0.4526,"d":"0.453"},"1:155104110:155106206:clu_12244_NA",155104110,155106206,"EFNA1","downstream_gene_variant","MODIFIER",-9840,{"v":0.839021,"d":"0.839"},{"v":0.0595193,"d":"0.060"},{"v":5.22e-33,"d":"5.22E-33"},{"v":1.7e-30,"d":"1.70E-30"},"ENST00000368406;ENST00000368407;ENST00000469878;ENST00000474413;ENST00000497282"]
["chr15","rs12441187","G","A",{"v":0.4708,"d":"0.471"},"15:34820035:34820126:clu_52452_NA",34820035,34820126,"-","upstream_gene_variant","MODIFIER",60899,{"v":-0.743796,"d":"-0.744"},{"v":0.0519275,"d":"0.052"},{"v":5.24e-33,"d":"5.24E-33"},{"v":1.71e-30,"d":"1.71E-30"},"ENST00000683415;ENST00000342314;ENST00000438958;ENST00000569100;ENST00000484716;ENST00000568555"]
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["chr18","18:14895118","CTTTA","C",{"v":0.3484,"d":"0.348"},"18:14787099:14791400:clu_55601_NA",14787099,14791400,"ANKRD30B","intergenic_region","MODIFIER",108018,{"v":-1.19406,"d":"-1.194"},{"v":0.079111,"d":"0.079"},1.15E-29,{"v":3.07e-27,"d":"3.07E-27"},"ENST00000579292;ENST00000690538;ENST00000358984;ENST00000665241;ENST00000580206"]
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["chr19","rs6509733","C","A",{"v":0.3436,"d":"0.344"},"19:53700515:53703877:clu_47144_NA",53700515,53703877,"-","upstream_gene_variant","MODIFIER",2232,{"v":-0.848755,"d":"-0.849"},{"v":0.0661833,"d":"0.066"},1.18E-29,{"v":3.14e-27,"d":"3.14E-27"},"ENST00000601072;ENST00000701908;ENST00000691098;ENST00000702127;ENST00000702819;ENST00000691047;ENST00000795206;ENST00000795207;ENST00000795209;ENST00000795208;ENST00000795210;ENST00000795213;ENST00000795220;ENST00000795221;ENST00000597550;ENST00000795211;ENST00000795219;ENST00000795212;ENST00000795214;ENST00000795215;ENST00000795216;ENST00000795217;ENST00000795218;ENST00000795223;ENST00000795224"]
["chr8","rs6985299","C","T",{"v":0.3868,"d":"0.387"},"8:71581773:71587053:clu_85404_NA",71581773,71587053,"-","intron_variant","MODIFIER",31305,{"v":0.532846,"d":"0.533"},{"v":0.0397272,"d":"0.040"},1.19E-29,{"v":3.17e-27,"d":"3.17E-27"},"ENST00000408926;ENST00000520092;ENST00000520030;ENST00000520273;ENST00000519350;ENST00000647843"]
["chr10","rs2902548","T","C",{"v":0.1636,"d":"0.164"},"10:104486914:104488188:clu_18005_NA",104486914,104488188,"SFXN2","downstream_gene_variant","MODIFIER",467,{"v":-1.17484,"d":"-1.175"},{"v":0.0805844,"d":"0.081"},{"v":1.3e-29,"d":"1.30E-29"},{"v":3.46e-27,"d":"3.46E-27"},"ENST00000602831;ENST00000602287;ENST00000480358;ENST00000602544;ENST00000602785;ENST00000602439;ENST00000602764;ENST00000459894;ENST00000369893;ENST00000602670;ENST00000602660;ENST00000602868"]
["chr12","rs10843860","C","A",{"v":0.3365,"d":"0.337"},"12:9736760:9756635:clu_57539_NA",9736760,9756635,"KLRB1","intron_variant","MODIFIER",-112519,{"v":-1.05845,"d":"-1.058"},{"v":0.0745333,"d":"0.075"},{"v":1.43e-29,"d":"1.43E-29"},{"v":3.8E-27,"d":"3.80E-27"},"ENST00000733153;ENST00000642112;ENST00000733152;ENST00000733156;ENST00000733157;ENST00000641304;ENST00000641608;ENST00000733155;ENST00000733154;ENST00000229402"]
["chr7","rs141352106","A","AAC",{"v":0.1222,"d":"0.122"},"7:102309451:102323726:clu_89974_NA",102309451,102323726,"POLR2J2;POLR2J2","upstream_gene_variant","MODIFIER",23219,{"v":-1.56767,"d":"-1.568"},{"v":0.119146,"d":"0.119"},{"v":1.46e-29,"d":"1.46E-29"},{"v":3.88e-27,"d":"3.88E-27"},"ENST00000639209;ENST00000476151;ENST00000358438;ENST00000333432;ENST00000460726"]
["chr6","rs62423548","A","T",0.359,"6:62388852:62390914:clu_73919_NA",62388852,62390914,"-","intron_variant","MODIFIER",34624,{"v":0.574795,"d":"0.575"},{"v":0.0323,"d":"0.032"},{"v":1.47e-29,"d":"1.47E-29"},{"v":3.9e-27,"d":"3.90E-27"},"ENST00000718012;ENST00000281156;ENST00000675091"]
["chr10","rs4746395","T","C",{"v":0.3525,"d":"0.353"},"10:78163124:78316967:clu_17077_NA",78163124,78316967,"C10orf11","intron_variant","MODIFIER",46206,{"v":0.649106,"d":"0.649"},{"v":0.0410564,"d":"0.041"},{"v":1.49e-29,"d":"1.49E-29"},{"v":3.95e-27,"d":"3.95E-27"},"ENST00000611255;ENST00000593699;ENST00000372499;ENST00000496424;ENST00000488655;ENST00000598708;ENST00000468134;ENST00000596228;ENST00000597823;ENST00000488759;ENST00000483375;ENST00000493194;ENST00000595936;ENST00000493690;ENST00000412137;ENST00000597938"]
["chr5","rs68083627","T","C",{"v":0.4295,"d":"0.430"},"5:68599756:68603778:clu_39498_NA",68599756,68603778,"-","intron_variant","MODIFIER",-2858,{"v":0.625248,"d":"0.625"},{"v":0.0450468,"d":"0.045"},{"v":1.49999999999999E-29,"d":"1.50E-29"},{"v":3.97e-27,"d":"3.97E-27"},"ENST00000396496;ENST00000396499;ENST00000460090;ENST00000383374;ENST00000511257;ENST00000512045"]
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["chr11","rs7104086:A:G","G","A",{"v":0.3087,"d":"0.309"},"11:125831893:125848199:clu_28589_NA",125831893,125848199,"CDON","intron_variant","MODIFIER",13379,{"v":-1.55761,"d":"-1.558"},{"v":0.0963414,"d":"0.096"},{"v":1.53e-29,"d":"1.53E-29"},{"v":4.04e-27,"d":"4.04E-27"},"ENST00000392693;ENST00000684078;ENST00000263577;ENST00000531738;ENST00000680589;ENST00000683597;ENST00000683716;ENST00000683981"]
["chr17","rs11314342","CT","C",0.172,"17:39884088:39884453:clu_68970_NA",39884088,39884453,"HAP1;JUP","upstream_gene_variant","MODIFIER",3078,{"v":1.46598,"d":"1.466"},{"v":0.112317,"d":"0.112"},{"v":1.58e-29,"d":"1.58E-29"},{"v":4.17e-27,"d":"4.17E-27"},"ENST00000393939;ENST00000347901;ENST00000310778;ENST00000341193"]
["chr2","rs6735570","G","C",{"v":0.3935,"d":"0.394"},"2:132285919:132287220:clu_3692_NA",132285919,132287220,"CCDC74A","intron_variant","MODIFIER",-13863,{"v":0.819275,"d":"0.819"},{"v":0.0636165,"d":"0.064"},{"v":1.61e-29,"d":"1.61E-29"},{"v":4.25e-27,"d":"4.25E-27"},"ENST00000465939;ENST00000295171;ENST00000467992;ENST00000454549;ENST00000409856;ENST00000468650;ENST00000478665;ENST00000434330"]
["chr6","rs62411930","G","A",{"v":0.3594,"d":"0.359"},"6:49409684:49411497:clu_73744_NA",49409684,49411497,"MUT","intron_variant","MODIFIER",10563,{"v":-0.672974,"d":"-0.673"},{"v":0.0493557,"d":"0.049"},{"v":1.64e-29,"d":"1.64E-29"},{"v":4.32e-27,"d":"4.32E-27"},"ENST00000274813"]
["chr9","rs12375624","A","G",{"v":0.4416,"d":"0.442"},"9:32989893:33024998:clu_29478_NA",32989893,33024998,"-","upstream_gene_variant","MODIFIER",27244,{"v":-0.592847,"d":"-0.593"},{"v":0.0461645,"d":"0.046"},{"v":1.66e-29,"d":"1.66E-29"},{"v":4.37e-27,"d":"4.37E-27"},"ENST00000379817;ENST00000436040;ENST00000465003;ENST00000460940;ENST00000309615;ENST00000379825;ENST00000397172;ENST00000379819;ENST00000379813;ENST00000467331;ENST00000474658;ENST00000476858;ENST00000468275;ENST00000472896;ENST00000463596;ENST00000477119;ENST00000479656;ENST00000478279;ENST00000672846;ENST00000473270;ENST00000672281;ENST00000495360;ENST00000460945;ENST00000482687;ENST00000485479;ENST00000480031;ENST00000483148;ENST00000464632;ENST00000494973;ENST00000671912;ENST00000672553;ENST00000489583;ENST00000672519;ENST00000672244;ENST00000673171;ENST00000673416;ENST00000673360;ENST00000494649;ENST00000673211;ENST00000672615;ENST00000673485;ENST00000672476;ENST00000672152;ENST00000672535;ENST00000673487;ENST00000672438;ENST00000673598;ENST00000672286;ENST00000673248;ENST00000813243;ENST00000425356"]
["chr6","rs543283","A","G",{"v":0.4887,"d":"0.489"},"6:125475678:125541224:clu_75138_NA",125475678,125541224,"TPD52L1;HDDC2","5_prime_UTR_variant","MODIFIER",-121,{"v":0.791455,"d":"0.791"},{"v":0.0607399,"d":"0.061"},{"v":1.67e-29,"d":"1.67E-29"},{"v":4.39e-27,"d":"4.39E-27"},"ENST00000304877;ENST00000368402;ENST00000368388;ENST00000527711;ENST00000392483;ENST00000528193;ENST00000532978;ENST00000392482;ENST00000524679;ENST00000532429;ENST00000534199;ENST00000534368;ENST00000534000;ENST00000848496;ENST00000608456"]
["chr20","rs59684388","A","G",{"v":0.1051,"d":"0.105"},"20:62033377:62033553:clu_83444_NA",62033377,62033553,"-","3_prime_UTR_variant","MODIFIER",209,{"v":-1.03755,"d":"-1.038"},{"v":0.0761884,"d":"0.076"},{"v":1.7e-29,"d":"1.70E-29"},{"v":4.47e-27,"d":"4.47E-27"},"ENST00000627221;ENST00000359125;ENST00000370224;ENST00000629241;ENST00000625514;ENST00000626839;ENST00000629676;ENST00000706989;ENST00000637632"]
["chr2","rs4583476","C","T",{"v":0.2588,"d":"0.259"},"2:3606588:3622641:clu_143_NA",3606588,3622641,"-","upstream_gene_variant","MODIFIER",2167,{"v":0.684681,"d":"0.685"},{"v":0.0414166,"d":"0.041"},{"v":1.93e-29,"d":"1.93E-29"},{"v":5.07e-27,"d":"5.07E-27"},"ENST00000426725;ENST00000664922;ENST00000438436;ENST00000797888;ENST00000797889;ENST00000797890;ENST00000797891;ENST00000797892;ENST00000656939;ENST00000671571"]
["chr17","rs7212571","C","G",{"v":0.3953,"d":"0.395"},"17:20295081:20303834:clu_68076_NA",20295081,20303834,"-","upstream_gene_variant","MODIFIER",-71930,{"v":0.5919,"d":"0.592"},{"v":0.0387913,"d":"0.039"},{"v":2.1e-29,"d":"2.10E-29"},{"v":5.51e-27,"d":"5.51E-27"},"ENST00000433419"]
["chr6","rs56246713","T","G",{"v":0.4273,"d":"0.427"},"6:41103080:41105095:clu_73343_NA",41103080,41105095,"-","splice_acceptor_variant&intron_variant","HIGH",2013,{"v":-0.868548,"d":"-0.869"},{"v":0.0684916,"d":"0.068"},{"v":2.19e-29,"d":"2.19E-29"},5.74E-27,"ENST00000457653;ENST00000567255"]
["chr16","rs27425","T","C",{"v":0.3814,"d":"0.381"},"16:2255968:2256062:clu_48239_NA",2255968,2256062,"MLST8","5_prime_UTR_premature_start_codon_gain_variant","LOW",-747,{"v":0.708207,"d":"0.708"},{"v":0.0445024,"d":"0.045"},{"v":2.2e-29,"d":"2.20E-29"},{"v":5.76e-27,"d":"5.76E-27"},"ENST00000563179;ENST00000301724;ENST00000397124;ENST00000561651;ENST00000562479;ENST00000562844;ENST00000563067;ENST00000563107;ENST00000564679;ENST00000569457;ENST00000564088;ENST00000382450;ENST00000562851;ENST00000564294;ENST00000570224;ENST00000562352;ENST00000565687;ENST00000568542;ENST00000565269;ENST00000566653;ENST00000567282;ENST00000565717;ENST00000568194;ENST00000566835;ENST00000565250;ENST00000567623;ENST00000565330;ENST00000567928;ENST00000569417"]
["chr6","rs146974816","T","C",{"v":0.06586,"d":"0.066"},"6:32916645:32917048:clu_72856_NA",32916645,32917048,"XXbac-BPG181M17.5;HLA-DMA","upstream_gene_variant","MODIFIER",8827,-1.898,{"v":0.11794,"d":"0.118"},{"v":2.23e-29,"d":"2.23E-29"},{"v":5.83e-27,"d":"5.83E-27"},"ENST00000429234;ENST00000480785;ENST00000395305;ENST00000395303;ENST00000477541;ENST00000374843;ENST00000464392;ENST00000456800"]
["chr10","rs4746395","T","C",{"v":0.3525,"d":"0.353"},"10:78084243:78316967:clu_17077_NA",78084243,78316967,"C10orf11","intron_variant","MODIFIER",125087,{"v":0.702165,"d":"0.702"},{"v":0.0519738,"d":"0.052"},{"v":2.37e-29,"d":"2.37E-29"},{"v":6.19e-27,"d":"6.19E-27"},"ENST00000611255;ENST00000593699;ENST00000372499;ENST00000496424;ENST00000488655;ENST00000598708;ENST00000468134;ENST00000596228;ENST00000597823;ENST00000488759;ENST00000483375;ENST00000493194;ENST00000595936;ENST00000493690;ENST00000412137;ENST00000597938"]
["chr6","rs72850021","G","A",{"v":0.1077,"d":"0.108"},"6:32487428:32489682:clu_72822_NA",32487428,32489682,"HLA-DRB5","intergenic_region","MODIFIER",86466,{"v":1.34888,"d":"1.349"},{"v":0.097022,"d":"0.097"},{"v":2.37e-29,"d":"2.37E-29"},{"v":6.19e-27,"d":"6.19E-27"},"ENST00000374975;ENST00000714490"]
["chr19","rs2860185","C","T",{"v":0.4712,"d":"0.471"},"19:6432215:6433498:clu_43210_NA",6432215,6433498,"-","3_prime_UTR_variant","MODIFIER",4006,{"v":0.713721,"d":"0.714"},{"v":0.0555316,"d":"0.056"},{"v":2.43e-29,"d":"2.43E-29"},{"v":6.34e-27,"d":"6.34E-27"},"ENST00000321510;ENST00000597558;ENST00000458275"]
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["chr19","rs56091459","C","CCTGT",{"v":0.2829,"d":"0.283"},"19:54970548:54970605:clu_47284_NA",54970548,54970605,"LENG8","upstream_gene_variant","MODIFIER",-14865,{"v":0.892661,"d":"0.893"},{"v":0.0671468,"d":"0.067"},{"v":1.83e-22,"d":"1.83E-22"},{"v":2.96e-20,"d":"2.96E-20"},"ENST00000326764;ENST00000376514;ENST00000610347;ENST00000421200"]
["chr8","rs16888728","T","C",0.179,"8:117791825:117798742:clu_86177_NA",117791825,117798742,"UTP23","upstream_gene_variant","MODIFIER",-7851,{"v":-0.893784,"d":"-0.894"},{"v":0.0811611,"d":"0.081"},{"v":1.83e-22,"d":"1.83E-22"},{"v":2.96e-20,"d":"2.96E-20"},"ENST00000521703;ENST00000517814;ENST00000521071;ENST00000517820;ENST00000520733;ENST00000524128"]
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["chr2","rs56368712","A","T",{"v":0.06691,"d":"0.067"},"2:47604653:47606092:clu_1439_NA",47604653,47606092,"EPCAM","upstream_gene_variant","MODIFIER",-4852,{"v":-1.25714,"d":"-1.257"},{"v":0.106499,"d":"0.106"},1.85E-22,{"v":2.98e-20,"d":"2.98E-20"},"ENST00000405271;ENST00000456133;ENST00000263735;ENST00000490733;ENST00000385188"]
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["chr12","rs11609337","T","C",{"v":0.1132,"d":"0.113"},"12:70636673:70637092:clu_59723_NA",70636673,70637092,"CNOT2","intron_variant","MODIFIER",-70327,{"v":-1.05233,"d":"-1.052"},{"v":0.0926921,"d":"0.093"},2.01E-22,{"v":3.24e-20,"d":"3.24E-20"},"ENST00000549419;ENST00000668518;ENST00000550216;ENST00000656495;ENST00000549651;ENST00000552998;ENST00000701750;ENST00000807800;ENST00000807799;ENST00000686629;ENST00000807797;ENST00000670041;ENST00000686072;ENST00000701960;ENST00000553135;ENST00000675475;ENST00000688862;ENST00000689831;ENST00000807801;ENST00000807802;ENST00000807805;ENST00000807803;ENST00000807812;ENST00000807806;ENST00000807804;ENST00000807807;ENST00000807811;ENST00000807810;ENST00000807809;ENST00000807808;ENST00000807813;ENST00000807816;ENST00000807815;ENST00000807814;ENST00000807817;ENST00000807821;ENST00000807825;ENST00000807823;ENST00000807822;ENST00000807818;ENST00000807819;ENST00000807824;ENST00000807827;ENST00000807826;ENST00000807828;ENST00000807820;ENST00000807829;ENST00000807834;ENST00000807835;ENST00000807839;ENST00000807838;ENST00000807837;ENST00000807832;ENST00000807830;ENST00000807833;ENST00000807840;ENST00000807831;ENST00000807836;ENST00000807841;ENST00000807843;ENST00000807842;ENST00000807844;ENST00000807845;ENST00000807850;ENST00000807846;ENST00000807848;ENST00000807849;ENST00000807847;ENST00000418359;ENST00000547780"]
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["chr2","rs144679488","AAG","AAGAG",{"v":0.1879,"d":"0.188"},"2:96563213:96564893:clu_2645_NA",96563213,96564893,"ANKRD36C","intergenic_region","MODIFIER",-153470,{"v":-1.68641,"d":"-1.686"},{"v":0.143422,"d":"0.143"},{"v":2.18e-22,"d":"2.18E-22"},{"v":3.51e-20,"d":"3.51E-20"},"ENST00000295246;ENST00000456556;ENST00000531153;ENST00000534304"]
["chr19","rs4803327","T","C",0.385,"19:40840811:40842017:clu_45738_NA",40840811,40842017,"C19orf47","splice_region_variant&intron_variant","LOW",-73,{"v":0.628122,"d":"0.628"},{"v":0.0496844,"d":"0.050"},{"v":2.2e-22,"d":"2.20E-22"},{"v":3.54e-20,"d":"3.54E-20"},"ENST00000683109;ENST00000582783;ENST00000392035;ENST00000357884;ENST00000582006;ENST00000580606;ENST00000580977"]
["chr8","rs9183","T","C",{"v":0.2326,"d":"0.233"},"8:28595180:28608174:clu_84605_NA",28595180,28608174,"EXTL3","3_prime_UTR_variant","MODIFIER",14588,{"v":0.569839,"d":"0.570"},{"v":0.0410206,"d":"0.041"},{"v":2.25e-22,"d":"2.25E-22"},{"v":3.61e-20,"d":"3.61E-20"},"ENST00000696177;ENST00000220562;ENST00000517738;ENST00000519886;ENST00000520679;ENST00000521473;ENST00000521532;ENST00000522698;ENST00000523271;ENST00000696178;ENST00000696179;ENST00000696181;ENST00000696180;ENST00000696182;ENST00000696184;ENST00000696186;ENST00000696188"]
["chr4","rs13140248","A","G",{"v":0.3961,"d":"0.396"},"4:186846868:186854090:clu_66550_NA",186846868,186854090,"SORBS2","downstream_gene_variant","MODIFIER",-4080,{"v":0.524208,"d":"0.524"},{"v":0.0434526,"d":"0.043"},{"v":2.26e-22,"d":"2.26E-22"},{"v":3.63e-20,"d":"3.63E-20"},"ENST00000284776;ENST00000355634;ENST00000431902;ENST00000415274;ENST00000421420;ENST00000432655;ENST00000488562;ENST00000469627;ENST00000476878;ENST00000444781;ENST00000698538"]
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["chr18","rs648383","C","G",{"v":0.3794,"d":"0.379"},"18:51809385:51809689:clu_56258_NA",51809385,51809689,"POLI","intergenic_region","MODIFIER",-30393,{"v":-0.634674,"d":"-0.635"},{"v":0.0556225,"d":"0.056"},{"v":2.68e-22,"d":"2.68E-22"},{"v":4.29e-20,"d":"4.29E-20"},"ENST00000579534;ENST00000406285;ENST00000579434;ENST00000217800;ENST00000581950;ENST00000585023;ENST00000579823"]
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["chr13","rs9536190","C","T",{"v":0.2774,"d":"0.277"},"13:53191817:53196124:clu_80408_NA",53191817,53196124,"-","intron_variant","MODIFIER",-10774,{"v":0.843577,"d":"0.844"},{"v":0.0742832,"d":"0.074"},{"v":9.53e-21,"d":"9.53E-21"},1.37E-18,"ENST00000740286;ENST00000740504;ENST00000740505;ENST00000740506;ENST00000740500;ENST00000342657;ENST00000614537;ENST00000740507;ENST00000740509;ENST00000740508;ENST00000613769;ENST00000398039;ENST00000740512;ENST00000740510;ENST00000740511;ENST00000683187;ENST00000740503;ENST00000740514;ENST00000740515;ENST00000740516;ENST00000740517;ENST00000740519;ENST00000740518;ENST00000740520;ENST00000740521;ENST00000740522;ENST00000740524;ENST00000740523;ENST00000740525;ENST00000740526;ENST00000740527;ENST00000740528;ENST00000509685"]
["chr6","rs1889472","A","T",{"v":0.3564,"d":"0.356"},"6:150206809:150217269:clu_75699_NA",150206809,150217269,"RAET1E","upstream_gene_variant","MODIFIER",-21301,{"v":-0.715621,"d":"-0.716"},{"v":0.0653883,"d":"0.065"},{"v":9.49e-21,"d":"9.49E-21"},1.37E-18,"ENST00000647612;ENST00000606915;ENST00000357183;ENST00000532335;ENST00000392270;ENST00000367363;ENST00000529948;ENST00000524905;ENST00000605899;ENST00000446954"]
["chr2","rs13423359","T","G",{"v":0.2801,"d":"0.280"},"2:27322708:27324965:clu_751_NA",27322708,27324965,"KHK;CGREF1","intron_variant","MODIFIER",12191,{"v":-0.723841,"d":"-0.724"},{"v":0.0685271,"d":"0.069"},{"v":9.68e-21,"d":"9.68E-21"},{"v":1.39e-18,"d":"1.39E-18"},"ENST00000260598;ENST00000260599;ENST00000490823;ENST00000429697;ENST00000464371;ENST00000440612;ENST00000402550;ENST00000640154;ENST00000402394;ENST00000405600;ENST00000312734;ENST00000404694"]
["chr3","rs11128927","C","G",{"v":0.3696,"d":"0.370"},"3:19924223:19925238:clu_33593_NA",19924223,19925238,"EFHB","5_prime_UTR_variant","MODIFIER",64213,{"v":-0.701731,"d":"-0.702"},{"v":0.0632531,"d":"0.063"},{"v":9.78e-21,"d":"9.78E-21"},{"v":1.4e-18,"d":"1.40E-18"},"ENST00000295824;ENST00000344838"]
["chr18","rs804782","G","T",{"v":0.4229,"d":"0.423"},"18:14813164:14814620:clu_55606_NA",14813164,14814620,"ANKRD30B","intergenic_region","MODIFIER",84446,{"v":0.721107,"d":"0.721"},{"v":0.0665293,"d":"0.067"},1.01E-20,1.45E-18,"ENST00000690538;ENST00000358984;ENST00000665241;ENST00000580206"]
["chr7","rs77215789","T","C",0.104,"7:29019714:29052666:clu_87948_NA",29019714,29052666,"CPVL","upstream_gene_variant","MODIFIER",16542,{"v":-1.00875,"d":"-1.009"},{"v":0.0915212,"d":"0.092"},1.02E-20,{"v":1.46e-18,"d":"1.46E-18"},"ENST00000749297;ENST00000749307;ENST00000609389;ENST00000670619;ENST00000749323;ENST00000608972;ENST00000609495;ENST00000749308;ENST00000749309;ENST00000749321;ENST00000749310;ENST00000749311;ENST00000749324;ENST00000749312;ENST00000749313;ENST00000749322;ENST00000749325;ENST00000749314;ENST00000749327;ENST00000411479;ENST00000749320;ENST00000749326;ENST00000749328;ENST00000749315;ENST00000749298;ENST00000749299;ENST00000749300;ENST00000749317;ENST00000749318;ENST00000749301;ENST00000749303;ENST00000749304;ENST00000749302;ENST00000749316;ENST00000749319;ENST00000749305;ENST00000749306;ENST00000265394;ENST00000396276;ENST00000432534;ENST00000455893;ENST00000409850"]
["chr2","rs34113296","G","T",{"v":0.1887,"d":"0.189"},"2:29240170:29247005:clu_924_NA",29240170,29247005,"FAM179A","upstream_gene_variant","MODIFIER",-87787,{"v":-0.719161,"d":"-0.719"},{"v":0.0630938,"d":"0.063"},1.07E-20,{"v":1.53e-18,"d":"1.53E-18"},"ENST00000401723;ENST00000379558;ENST00000465300;ENST00000440012"]
["chr21","rs60361835","C","G",{"v":0.1021,"d":"0.102"},"21:27102112:27106644:clu_62102_NA",27102112,27106644,"ATP5J","upstream_gene_variant","MODIFIER",3135,{"v":1.0712,"d":"1.071"},{"v":0.0984634,"d":"0.098"},1.15E-20,{"v":1.65e-18,"d":"1.65E-18"},"ENST00000400099;ENST00000400094;ENST00000457143;ENST00000400090;ENST00000400087;ENST00000400093;ENST00000284971;ENST00000486002"]
["chr16","rs3803700","A","G",{"v":0.4656,"d":"0.466"},"16:1025995:1026327:clu_47966_NA",1025995,1026327,"LMF1","splice_region_variant&intron_variant","LOW",1103,{"v":-0.531904,"d":"-0.532"},{"v":0.0477701,"d":"0.048"},1.16E-20,1.66E-18,"ENST00000545827;ENST00000570014;ENST00000563863;ENST00000711632;ENST00000562570;ENST00000565069;ENST00000565139;ENST00000565467;ENST00000568394;ENST00000655952;ENST00000662104;ENST00000711634;ENST00000711638;ENST00000567961;ENST00000711642;ENST00000711651;ENST00000711633;ENST00000711637;ENST00000711639;ENST00000669274;ENST00000711640;ENST00000711641;ENST00000711635;ENST00000711636;ENST00000711643;ENST00000711644;ENST00000711652;ENST00000711645;ENST00000711646;ENST00000711653"]
["chr15","rs62026703","G","T",{"v":0.4358,"d":"0.436"},"15:45545622:45545979:clu_53086_NA",45545622,45545979,"SLC28A2","3_prime_UTR_variant","MODIFIER",24306,{"v":0.835851,"d":"0.836"},{"v":0.0746406,"d":"0.075"},1.16E-20,1.66E-18,"ENST00000663463;ENST00000758522;ENST00000758521;ENST00000758520;ENST00000559003;ENST00000560344;ENST00000560438;ENST00000347644"]
["chr15","rs62026703","G","T",{"v":0.4358,"d":"0.436"},"15:45548196:45556825:clu_53087_NA",45548196,45556825,"SLC28A2","3_prime_UTR_variant","MODIFIER",21732,{"v":0.778967,"d":"0.779"},{"v":0.0731958,"d":"0.073"},1.16E-20,1.66E-18,"ENST00000663463;ENST00000758522;ENST00000758521;ENST00000758520;ENST00000559003;ENST00000560344;ENST00000561404;ENST00000560438;ENST00000347644;ENST00000559924"]
["chr1","rs659061","G","A",{"v":0.4004,"d":"0.400"},"1:58999132:58999625:clu_9828_NA",58999132,58999625,"OMA1;DAB1","intron_variant","MODIFIER",25302,{"v":0.550413,"d":"0.550"},{"v":0.048861,"d":"0.049"},1.17E-20,1.67E-18,"ENST00000485760;ENST00000421528;ENST00000371226"]
["chr5","rs10475105","A","G",{"v":0.2468,"d":"0.247"},"5:17404429:17441578:clu_38683_NA",17404429,17441578,"-","intron_variant","MODIFIER",5128,{"v":-0.845444,"d":"-0.845"},{"v":0.0795767,"d":"0.080"},{"v":1.2E-20,"d":"1.20E-20"},1.71E-18,"ENST00000652939;ENST00000659183;ENST00000668161;ENST00000505844;ENST00000507730;ENST00000508677;ENST00000653252;ENST00000658949;ENST00000659626;ENST00000653381;ENST00000663179;ENST00000663823;ENST00000666256;ENST00000668135;ENST00000690358;ENST00000817228;ENST00000817229;ENST00000817230;ENST00000817231;ENST00000817232;ENST00000817233;ENST00000817236;ENST00000669610;ENST00000817234;ENST00000817235;ENST00000669953;ENST00000671029;ENST00000689234;ENST00000702313;ENST00000817227"]
["chr10","rs2902548","T","C",{"v":0.1636,"d":"0.164"},"10:104487548:104488188:clu_18005_NA",104487548,104488188,"SFXN2","downstream_gene_variant","MODIFIER",-167,{"v":0.809628,"d":"0.810"},{"v":0.0726498,"d":"0.073"},{"v":1.2E-20,"d":"1.20E-20"},1.71E-18,"ENST00000602831;ENST00000602287;ENST00000480358;ENST00000602544;ENST00000602439;ENST00000602764;ENST00000459894;ENST00000369893;ENST00000602660;ENST00000602868"]
["chr3","rs3804587","T","C",{"v":0.2718,"d":"0.272"},"3:125691068:125691318:clu_36311_NA",125691068,125691318,"ROPN1B","upstream_gene_variant","MODIFIER",46552,{"v":0.646867,"d":"0.647"},{"v":0.0522552,"d":"0.052"},1.21E-20,1.73E-18,"ENST00000683534;ENST00000686881;ENST00000688157;ENST00000685081;ENST00000687048;ENST00000687245;ENST00000687460;ENST00000686211;ENST00000688098;ENST00000774394;ENST00000689775;ENST00000774395;ENST00000774396;ENST00000774399;ENST00000690016;ENST00000774397;ENST00000774408;ENST00000774409;ENST00000774407;ENST00000702325;ENST00000774401;ENST00000692424;ENST00000692801;ENST00000692036;ENST00000702064;ENST00000774400;ENST00000774405;ENST00000693330;ENST00000701061;ENST00000774398;ENST00000774403;ENST00000774404;ENST00000702240;ENST00000774402;ENST00000774410;ENST00000774411;ENST00000774429;ENST00000774412;ENST00000774406;ENST00000682163;ENST00000685849;ENST00000611639;ENST00000251776;ENST00000504401;ENST00000514116;ENST00000513830;ENST00000511862;ENST00000511035;ENST00000508088;ENST00000510450"]
["chr3","rs4857414","T","C",0.385,"3:98437365:98452343:clu_35626_NA",98437365,98452343,"ST3GAL6","upstream_gene_variant","MODIFIER",-4807,{"v":0.619265,"d":"0.619"},{"v":0.0533657,"d":"0.053"},1.21E-20,1.73E-18,"ENST00000654703;ENST00000661245;ENST00000461931;ENST00000670291;ENST00000660566;ENST00000475816;ENST00000488132;ENST00000658186;ENST00000654439;ENST00000664787;ENST00000667720;ENST00000667875;ENST00000757765;ENST00000667022;ENST00000757766;ENST00000757768;ENST00000757767;ENST00000757769;ENST00000757772;ENST00000666744;ENST00000757771;ENST00000757770;ENST00000265261;ENST00000460774;ENST00000469105;ENST00000466482;ENST00000462152;ENST00000489112;ENST00000394162;ENST00000465004;ENST00000480133;ENST00000486334;ENST00000497008;ENST00000613264;ENST00000486249"]
["chr10","rs1362999","C","T",{"v":0.4136,"d":"0.414"},"10:35610598:35623826:clu_16130_NA",35610598,35623826,"CCNY","intron_variant","MODIFIER",141951,{"v":-0.557798,"d":"-0.558"},{"v":0.0455636,"d":"0.046"},1.22E-20,1.74E-18,"ENST00000811022;ENST00000605499;ENST00000659251;ENST00000715770;ENST00000811023;ENST00000811024;ENST00000811025;ENST00000811026;ENST00000811027;ENST00000811028;ENST00000811029;ENST00000811030;ENST00000490012;ENST00000374706;ENST00000493157"]
["chr6","rs3021304","C","G",{"v":0.4991,"d":"0.499"},"6:32546881:32548024:clu_72816_NA",32546881,32548024,"HLA-DRB1","intergenic_region","MODIFIER",28776,{"v":0.803106,"d":"0.803"},{"v":0.0694915,"d":"0.069"},{"v":1.23e-20,"d":"1.23E-20"},{"v":1.75e-18,"d":"1.75E-18"},"ENST00000696610;ENST00000696611;ENST00000696612;ENST00000360004;ENST00000696613"]
["chr17","rs36048409","A","T",{"v":0.2435,"d":"0.244"},"17:80141808:80146066:clu_71515_NA",80141808,80146066,"CCDC57","upstream_gene_variant","MODIFIER",-44848,{"v":0.563022,"d":"0.563"},{"v":0.0391281,"d":"0.039"},1.31E-20,{"v":1.87e-18,"d":"1.87E-18"},"ENST00000389641;ENST00000578910;ENST00000392343;ENST00000327026;ENST00000665763;ENST00000694881;ENST00000694882"]
["chr20","rs200899","A","G",{"v":0.4005,"d":"0.401"},"20:1787445:1791200:clu_81376_NA",1787445,1791200,"-","intron_variant","MODIFIER",1192,{"v":-0.98412,"d":"-0.984"},{"v":0.0895991,"d":"0.090"},{"v":1.33e-20,"d":"1.33E-20"},1.89E-18,"ENST00000447206;ENST00000716593;ENST00000844973;ENST00000844974;ENST00000844972;ENST00000716594;ENST00000844975;ENST00000668670;ENST00000844954;ENST00000844955;ENST00000844976;ENST00000654380;ENST00000655119;ENST00000666681;ENST00000671643;ENST00000844951;ENST00000844962;ENST00000844961;ENST00000702291;ENST00000844960;ENST00000844959;ENST00000844956;ENST00000844952;ENST00000844950;ENST00000844958;ENST00000844957;ENST00000844953;ENST00000844963;ENST00000844965;ENST00000844966;ENST00000844964;ENST00000844949;ENST00000844967;ENST00000844978;ENST00000658107;ENST00000844968;ENST00000844969;ENST00000844970;ENST00000844977;ENST00000844979;ENST00000661517;ENST00000653463;ENST00000844971;ENST00000844983;ENST00000844984;ENST00000844985;ENST00000844988;ENST00000844989;ENST00000844990;ENST00000845445"]
["chr19","rs56029016","A","T",{"v":0.1916,"d":"0.192"},"19:52452605:52479644:clu_47047_NA",52452605,52479644,"ZNF350","downstream_gene_variant","MODIFIER",-144,{"v":-0.737352,"d":"-0.737"},{"v":0.0691382,"d":"0.069"},{"v":1.34e-20,"d":"1.34E-20"},{"v":1.91e-18,"d":"1.91E-18"},"ENST00000595010;ENST00000797553;ENST00000797557;ENST00000692818;ENST00000600253;ENST00000797558;ENST00000658402;ENST00000661211;ENST00000797560;ENST00000797559;ENST00000797554;ENST00000797556;ENST00000797555;ENST00000243644;ENST00000601430;ENST00000600703;ENST00000598254;ENST00000594929;ENST00000597788;ENST00000593596;ENST00000597555"]
["chr10","rs1362999","C","T",{"v":0.4136,"d":"0.414"},"10:35527479:35579587:clu_16130_NA",35527479,35579587,"CCNY","intron_variant","MODIFIER",225070,{"v":-0.551678,"d":"-0.552"},{"v":0.0458609,"d":"0.046"},1.35E-20,{"v":1.92e-18,"d":"1.92E-18"},"ENST00000811022;ENST00000811032;ENST00000715770;ENST00000811023;ENST00000811024;ENST00000811025;ENST00000811026;ENST00000811027;ENST00000811028;ENST00000811029;ENST00000811030;ENST00000811031;ENST00000811033;ENST00000811034;ENST00000490012;ENST00000374706;ENST00000493157;ENST00000363227"]
["chr19","rs2972544","A","G",{"v":0.3794,"d":"0.379"},"19:36813127:36821155:clu_45372_NA",36813127,36821155,"-","upstream_gene_variant","MODIFIER",-60907,{"v":-0.688455,"d":"-0.688"},{"v":0.0644631,"d":"0.064"},1.37E-20,1.95E-18,"ENST00000427868;ENST00000662398;ENST00000675167;ENST00000438368;ENST00000590622;ENST00000651681;ENST00000591372;ENST00000658301;ENST00000585356;ENST00000412740;ENST00000590657;ENST00000667829;ENST00000656137;ENST00000658042;ENST00000666458;ENST00000667789;ENST00000658991;ENST00000668768;ENST00000675074;ENST00000661195;ENST00000689532;ENST00000784952;ENST00000449434;ENST00000668927;ENST00000784953;ENST00000658126;ENST00000659786;ENST00000666182;ENST00000691592;ENST00000675914;ENST00000676298;ENST00000702802;ENST00000702867;ENST00000784954;ENST00000784956;ENST00000784955;ENST00000784957"]
["chr5","rs2351245","T","G",{"v":0.2309,"d":"0.231"},"5:96038619:96058343:clu_40184_NA",96038619,96058343,"CAST","upstream_gene_variant","MODIFIER",-42887,{"v":-0.775318,"d":"-0.775"},{"v":0.0696914,"d":"0.070"},{"v":1.38e-20,"d":"1.38E-20"},1.96E-18,"ENST00000505143;ENST00000338252;ENST00000507487;ENST00000341926;ENST00000395812;ENST00000506811;ENST00000505402;ENST00000395813;ENST00000309190;ENST00000421689;ENST00000508117;ENST00000504221;ENST00000513666;ENST00000508197;ENST00000508830;ENST00000504465;ENST00000508608;ENST00000510756;ENST00000675479;ENST00000718091;ENST00000718093;ENST00000675107;ENST00000511097;ENST00000674702;ENST00000675179;ENST00000674984;ENST00000512620;ENST00000514845;ENST00000675663;ENST00000514055;ENST00000675033;ENST00000675267;ENST00000675266;ENST00000675614;ENST00000675858;ENST00000511049;ENST00000510156;ENST00000509903;ENST00000511782;ENST00000674587"]
["chr9","rs2784066","T","C",{"v":0.3416,"d":"0.342"},"9:139663130:139664534:clu_32642_NA",139663130,139664534,"-","upstream_gene_variant","MODIFIER",-8194,{"v":-0.664214,"d":"-0.664"},{"v":0.059083,"d":"0.059"},{"v":1.39e-20,"d":"1.39E-20"},{"v":1.97e-18,"d":"1.97E-18"}]
["chr12","rs1165692","A","G",{"v":0.4137,"d":"0.414"},"12:104341208:104341411:clu_60442_NA",104341208,104341411,"HSP90B1","upstream_gene_variant","MODIFIER",-1231,{"v":-0.801005,"d":"-0.801"},{"v":0.0608606,"d":"0.061"},{"v":1.4e-20,"d":"1.40E-20"},{"v":1.99e-18,"d":"1.99E-18"},"ENST00000299767;ENST00000548462;ENST00000550595;ENST00000679861;ENST00000680316;ENST00000681245;ENST00000552051;ENST00000679538;ENST00000680370;ENST00000681698;ENST00000680478;ENST00000681174;ENST00000614327;ENST00000680281;ENST00000679779;ENST00000680391;ENST00000680653;ENST00000681172;ENST00000680663;ENST00000680899;ENST00000680989;ENST00000681704;ENST00000681861;ENST00000681910;ENST00000681941;ENST00000681949;ENST00000651157"]
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["chr7","rs13234869","C","G",{"v":0.3865,"d":"0.387"},"7:64442494:64466919:clu_88647_NA",64442494,64466919,"ZNF117;ERV3-1","downstream_gene_variant","MODIFIER",-26960,{"v":-0.635933,"d":"-0.636"},{"v":0.0575589,"d":"0.058"},7.36E-20,{"v":9.86e-18,"d":"9.86E-18"},"ENST00000714026;ENST00000282869;ENST00000714027;ENST00000487644;ENST00000394323;ENST00000528878;ENST00000535538"]
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["chr6","rs3832453","G","GTTT",{"v":0.1525,"d":"0.153"},"6:168431260:168431453:clu_76170_NA",168431260,168431453,"KIF25","upstream_gene_variant","MODIFIER",-37432,{"v":-1.04699,"d":"-1.047"},{"v":0.111012,"d":"0.111"},2.38E-15,2.14E-13,"ENST00000643607;ENST00000443060;ENST00000652547;ENST00000644536;ENST00000645382;ENST00000504593"]
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["chr16","rs56112321","C","T",{"v":0.2033,"d":"0.203"},"16:89783230:89784854:clu_51760_NA",89783230,89784854,"VPS9D1","upstream_gene_variant","MODIFIER",2589,{"v":0.604031,"d":"0.604"},{"v":0.0545415,"d":"0.055"},{"v":8.37e-14,"d":"8.37E-14"},6.49E-12,"ENST00000561976;ENST00000389386;ENST00000563798;ENST00000562866;ENST00000562298"]
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["chr22","rs73164022","A","G",{"v":0.07944,"d":"0.079"},"22:32591794:32598320:clu_22910_NA",32591794,32598320,"RFPL2","upstream_gene_variant","MODIFIER",-6153,{"v":0.727983,"d":"0.728"},{"v":0.074218,"d":"0.074"},{"v":2.04e-10,"d":"2.04E-10"},{"v":1.12e-08,"d":"1.12E-08"},"ENST00000248983;ENST00000626996;ENST00000400237;ENST00000652607;ENST00000628378;ENST00000523725"]
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["chr12","rs3782513","C","A",0.381,"12:29503001:29510556:clu_58057_NA",29503001,29510556,"ERGIC2","upstream_gene_variant","MODIFIER",3252,{"v":0.456399,"d":"0.456"},{"v":0.0582669,"d":"0.058"},{"v":3.02e-10,"d":"3.02E-10"},{"v":1.63E-8,"d":"1.63E-08"},"ENST00000360150;ENST00000548909;ENST00000551467;ENST00000546509;ENST00000552155;ENST00000546839;ENST00000550353;ENST00000552132"]
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["chr14","rs74036657","T","G",{"v":0.04283,"d":"0.043"},"14:24911001:24911552:clu_19499_NA",24911001,24911552,"SDR39U1","intron_variant","MODIFIER",16362,{"v":1.15906,"d":"1.159"},{"v":0.133979,"d":"0.134"},{"v":5.18e-10,"d":"5.18E-10"},{"v":2.72e-08,"d":"2.72E-08"},"ENST00000251343;ENST00000553935;ENST00000399395;ENST00000544691;ENST00000553930;ENST00000538105;ENST00000553343;ENST00000553937;ENST00000554698;ENST00000554947;ENST00000555225;ENST00000555355;ENST00000555365;ENST00000555778;ENST00000555830;ENST00000556175;ENST00000556249;ENST00000556262;ENST00000556523;ENST00000556548;ENST00000556707"]
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["chr6","rs6455468","T","G",{"v":0.2101,"d":"0.210"},"6:168404383:168405929:clu_76169_NA",168404383,168405929,"KIF25","upstream_gene_variant","MODIFIER",-19439,{"v":-0.606365,"d":"-0.606"},{"v":0.0732073,"d":"0.073"},{"v":6.75e-10,"d":"6.75E-10"},{"v":3.49e-08,"d":"3.49E-08"},"ENST00000515361;ENST00000643607;ENST00000443060;ENST00000652547"]
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["chr2","rs116637277","G","A",{"v":0.05773,"d":"0.058"},"2:109405422:109408168:clu_3158_NA",109405422,109408168,"CCDC138","downstream_gene_variant","MODIFIER",-49993,{"v":0.666323,"d":"0.666"},{"v":0.0664204,"d":"0.066"},7.79E-10,{"v":4e-08,"d":"4.00E-08"},"ENST00000412964;ENST00000409529;ENST00000295124;ENST00000470608;ENST00000447782"]
["chr18","rs1945168","C","T",{"v":0.4323,"d":"0.432"},"18:22121626:22123753:clu_55769_NA",22121626,22123753,"-","upstream_gene_variant","MODIFIER",2791,{"v":-0.449395,"d":"-0.449"},{"v":0.0576338,"d":"0.058"},{"v":8.28e-10,"d":"8.28E-10"},{"v":4.24e-08,"d":"4.24E-08"},"ENST00000581648;ENST00000668994;ENST00000662616;ENST00000664008;ENST00000762860"]
["chr19","rs3746037","C","A",{"v":0.2077,"d":"0.208"},"19:1825942:1826877:clu_42709_NA",1825942,1826877,"REXO1","downstream_gene_variant","MODIFIER",3005,{"v":-0.729433,"d":"-0.729"},{"v":0.0985712,"d":"0.099"},{"v":8.61e-10,"d":"8.61E-10"},{"v":4.4e-08,"d":"4.40E-08"},"ENST00000170168"]
["chr11","rs1497119","G","A",{"v":0.1013,"d":"0.101"},"11:82428760:82428857:clu_27337_NA",82428760,82428857,"-","downstream_gene_variant","MODIFIER",-25853,{"v":-0.667713,"d":"-0.668"},{"v":0.0855293,"d":"0.086"},{"v":9.02e-10,"d":"9.02E-10"},{"v":4.6e-08,"d":"4.60E-08"},"ENST00000532217;ENST00000671287"]
["chr20","rs3842812","T","G",{"v":0.3799,"d":"0.380"},"20:13983050:13990466:clu_81772_NA",13983050,13990466,"MACROD2","upstream_gene_variant","MODIFIER",1051,{"v":0.345537,"d":"0.346"},{"v":0.0407513,"d":"0.041"},{"v":9.47e-10,"d":"9.47E-10"},{"v":4.82e-08,"d":"4.82E-08"},"ENST00000217246;ENST00000477147;ENST00000483997;ENST00000492055;ENST00000684519;ENST00000642719;ENST00000462552;ENST00000494602;ENST00000490428;ENST00000456781"]
["chr3","rs4974114","A","G",{"v":0.4725,"d":"0.473"},"3:55922577:55984453:clu_35087_NA",55922577,55984453,"ERC2","intron_variant","MODIFIER",90273,{"v":-0.440195,"d":"-0.440"},{"v":0.0557378,"d":"0.056"},{"v":9.7e-10,"d":"9.70E-10"},{"v":4.93e-08,"d":"4.93E-08"},"ENST00000288221;ENST00000492584;ENST00000460849"]
["chr22","rs11367508","A","AT",{"v":0.1768,"d":"0.177"},"22:25625545:25855383:clu_22543_NA",25625545,25855383,"CRYBB2;LRP5L","downstream_gene_variant","MODIFIER",236460,{"v":0.790435,"d":"0.790"},{"v":0.0910276,"d":"0.091"},{"v":1.01E-9,"d":"1.01E-09"},{"v":5.12e-08,"d":"5.12E-08"},"ENST00000651629;ENST00000398215;ENST00000757144;ENST00000623422;ENST00000823016;ENST00000823017;ENST00000823018;ENST00000823021;ENST00000823020;ENST00000823019;ENST00000411511;ENST00000823024;ENST00000823023;ENST00000823022;ENST00000823027;ENST00000823026;ENST00000823025;ENST00000823028;ENST00000432495;ENST00000822740;ENST00000822741;ENST00000650352;ENST00000649082;ENST00000412472;ENST00000773434;ENST00000773436;ENST00000773437;ENST00000773438;ENST00000773439;ENST00000773440;ENST00000773435;ENST00000773433;ENST00000433457;ENST00000434827;ENST00000467672;ENST00000444995;ENST00000650168;ENST00000402785;ENST00000474163;ENST00000484509;ENST00000468442;ENST00000650500;ENST00000818584;ENST00000818586;ENST00000818585;ENST00000818589;ENST00000818588;ENST00000818590;ENST00000818578;ENST00000818591;ENST00000818593;ENST00000818592;ENST00000818579;ENST00000818583;ENST00000818581;ENST00000818580;ENST00000818582;ENST00000818587;ENST00000609964;ENST00000603243;ENST00000382734;ENST00000818139;ENST00000701000;ENST00000818137;ENST00000818138;ENST00000686640;ENST00000509460;ENST00000702203;ENST00000818132;ENST00000818133;ENST00000354451;ENST00000702041;ENST00000818131;ENST00000818134;ENST00000818135;ENST00000818136;ENST00000818148;ENST00000818140;ENST00000818141;ENST00000818143;ENST00000818144;ENST00000818145;ENST00000818146;ENST00000818147;ENST00000415709"]
["chr4","rs10027319","G","A",{"v":0.3385,"d":"0.339"},"4:9037766:9065968:clu_63555_NA",9037766,9065968,"-","intron_variant","MODIFIER",339454,{"v":-0.698995,"d":"-0.699"},{"v":0.0711678,"d":"0.071"},{"v":1.06e-09,"d":"1.06E-09"},{"v":5.36e-08,"d":"5.36E-08"},"ENST00000811160;ENST00000811161;ENST00000810922;ENST00000810923;ENST00000659603;ENST00000662683;ENST00000666840;ENST00000810931;ENST00000810930;ENST00000810929;ENST00000810933;ENST00000810927;ENST00000810926;ENST00000810925;ENST00000810932;ENST00000810924;ENST00000810934;ENST00000810928;ENST00000810935;ENST00000810936;ENST00000810937;ENST00000810938;ENST00000810939;ENST00000810940;ENST00000810941;ENST00000810943;ENST00000810945;ENST00000506029"]
["chr9","9:12744512","TCTC","T",0.472,"9:12688550:12704515:clu_29136_NA",12688550,12704515,"TYRP1","intron_variant","MODIFIER",55961,{"v":0.576287,"d":"0.576"},{"v":0.0770235,"d":"0.077"},{"v":1.09E-9,"d":"1.09E-09"},{"v":5.51e-08,"d":"5.51E-08"},"ENST00000803542;ENST00000803544;ENST00000803543;ENST00000650458;ENST00000803545;ENST00000654076;ENST00000417638;ENST00000473763;ENST00000459790;ENST00000388918;ENST00000381136;ENST00000381142;ENST00000470909"]
["chr9","rs34135115","C","CT",{"v":0.3003,"d":"0.300"},"9:34179238:34216672:clu_29554_NA",34179238,34216672,"UBAP1","downstream_gene_variant","MODIFIER",143924,{"v":0.503865,"d":"0.504"},{"v":0.0643978,"d":"0.064"},{"v":1.11e-09,"d":"1.11E-09"},{"v":5.6e-08,"d":"5.60E-08"},"ENST00000625521;ENST00000379186;ENST00000297661;ENST00000626262;ENST00000439099;ENST00000363271;ENST00000516355"]
["chr10","rs4962352","G","A",{"v":0.2538,"d":"0.254"},"10:128351668:128358810:clu_18643_NA",128351668,128358810,"C10orf90","intron_variant","MODIFIER",-382,{"v":-0.468018,"d":"-0.468"},{"v":0.0575485,"d":"0.058"},{"v":1.15E-9,"d":"1.15E-09"},{"v":5.78e-08,"d":"5.78E-08"},"ENST00000488181;ENST00000657225"]
["chr2","rs55785599","A","C",{"v":0.3631,"d":"0.363"},"2:29084174:29092445:clu_902_NA",29084174,29092445,"TRMT61B","upstream_gene_variant","MODIFIER",3639,{"v":-0.48352,"d":"-0.484"},{"v":0.0623607,"d":"0.062"},{"v":1.17e-09,"d":"1.17E-09"},{"v":5.87e-08,"d":"5.87E-08"},"ENST00000306108;ENST00000439947;ENST00000490390;ENST00000484060"]
["chr11","rs2622422","C","G",0.047,"11:63993052:63993522:clu_26148_NA",63993052,63993522,"TRPT1;NUDT22","intron_variant","MODIFIER",-64994,{"v":-1.3325,"d":"-1.333"},{"v":0.17827,"d":"0.178"},{"v":1.19E-9,"d":"1.19E-09"},{"v":5.97e-08,"d":"5.97E-08"},"ENST00000394547;ENST00000394546;ENST00000541278;ENST00000317459;ENST00000539436;ENST00000537907;ENST00000546089;ENST00000539595;ENST00000536234;ENST00000545812;ENST00000542040;ENST00000540472;ENST00000539325"]
["chr17","rs148536805","C","T",{"v":0.2476,"d":"0.248"},"17:43698518:43699274:clu_69444_NA",43698518,43699274,"CRHR1","intron_variant","MODIFIER",396948,{"v":0.807456,"d":"0.807"},{"v":0.10352,"d":"0.104"},{"v":1.21E-9,"d":"1.21E-09"},{"v":6.05e-08,"d":"6.05E-08"},"ENST00000585118;ENST00000591271;ENST00000582491;ENST00000583740;ENST00000585122;ENST00000455565;ENST00000580220;ENST00000634540"]
["chr1","rs880633","C","T",0.414,"1:203151432:203151859:clu_13793_NA",203151432,203151859,"CHI3L1","upstream_gene_variant","MODIFIER",1368,{"v":0.4353,"d":"0.435"},{"v":0.0513565,"d":"0.051"},{"v":1.28e-09,"d":"1.28E-09"},{"v":6.38e-08,"d":"6.38E-08"},"ENST00000255409;ENST00000404436;ENST00000472064"]
["chr11","rs11038413","A","T",{"v":0.2967,"d":"0.297"},"11:45463285:45464287:clu_25383_NA",45463285,45464287,"-","downstream_gene_variant","MODIFIER",-78416,{"v":0.513309,"d":"0.513"},{"v":0.0655337,"d":"0.066"},{"v":1.33E-9,"d":"1.33E-09"},{"v":6.62e-08,"d":"6.62E-08"},"ENST00000781085;ENST00000781086;ENST00000781084;ENST00000528445"]
["chr10","rs7919804","C","G",{"v":0.4286,"d":"0.429"},"10:16478869:16479356:clu_15708_NA",16478869,16479356,"PTER","intron_variant","MODIFIER",11519,{"v":0.443568,"d":"0.444"},{"v":0.0555072,"d":"0.056"},{"v":1.34e-09,"d":"1.34E-09"},{"v":6.67e-08,"d":"6.67E-08"},"ENST00000423462;ENST00000378000;ENST00000535784"]
["chr15","rs16971478","G","A",{"v":0.04174,"d":"0.042"},"15:80191467:80206930:clu_54313_NA",80191467,80206930,"ST20;ST20-MTHFS","upstream_gene_variant","MODIFIER",-19497,{"v":0.859587,"d":"0.860"},{"v":0.0868892,"d":"0.087"},{"v":1.4e-09,"d":"1.40E-09"},{"v":6.94e-08,"d":"6.94E-08"},"ENST00000615374;ENST00000479961;ENST00000494999;ENST00000562759;ENST00000478497;ENST00000485386;ENST00000674427"]
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["chr2","rs139575450","T","TTACTC",{"v":0.2683,"d":"0.268"},"2:202285429:202315760:clu_5153_NA",202285429,202315760,"STRADB;TRAK2","upstream_gene_variant","MODIFIER",-28464,{"v":0.451802,"d":"0.452"},{"v":0.0367821,"d":"0.037"},{"v":1.69E-9,"d":"1.69E-09"},{"v":8.28E-8,"d":"8.28E-08"},"ENST00000332624;ENST00000430254;ENST00000451703;ENST00000440597;ENST00000458269;ENST00000365138"]
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["chr19","rs3786675","T","C",{"v":0.0514,"d":"0.051"},"19:50484270:50491629:clu_46843_NA",50484270,50491629,"VRK3","upstream_gene_variant","MODIFIER",22095,{"v":1.1817,"d":"1.182"},{"v":0.157341,"d":"0.157"},{"v":1.94e-09,"d":"1.94E-09"},{"v":9.44e-08,"d":"9.44E-08"},"ENST00000316763;ENST00000377011;ENST00000594948;ENST00000593919;ENST00000594090;ENST00000594092;ENST00000593912;ENST00000596814;ENST00000598553;ENST00000600284;ENST00000601341;ENST00000601912;ENST00000599538"]
["chr9","rs12005354","T","C",{"v":0.4272,"d":"0.427"},"9:33572367:33574838:clu_29528_NA",33572367,33574838,"ANKRD18B","upstream_gene_variant","MODIFIER",-50376,{"v":-0.322042,"d":"-0.322"},{"v":0.0404043,"d":"0.040"},{"v":2.01e-09,"d":"2.01E-09"},{"v":9.76E-8,"d":"9.76E-08"},"ENST00000684830;ENST00000290943;ENST00000703206;ENST00000357927;ENST00000703167;ENST00000437894"]
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["chr21","rs73907171","A","C",{"v":0.0298,"d":"0.030"},"21:45752172:45752916:clu_62714_NA",45752172,45752916,"C21orf2","upstream_gene_variant","MODIFIER",-93,{"v":1.02553,"d":"1.026"},{"v":0.102067,"d":"0.102"},{"v":2.51e-09,"d":"2.51E-09"},{"v":1.2e-07,"d":"1.20E-07"},"ENST00000339818;ENST00000496321;ENST00000462742;ENST00000397956;ENST00000325223;ENST00000478674;ENST00000448927"]
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["chr17","17:44258446","G","A",{"v":0.09034,"d":"0.090"},"17:44230335:44248221:clu_69467_NA",44230335,44248221,"KANSL1","intron_variant","MODIFIER",28110,{"v":0.748724,"d":"0.749"},{"v":0.0629315,"d":"0.063"},{"v":3.65E-9,"d":"3.65E-09"},{"v":1.72E-7,"d":"1.72E-07"},"ENST00000432791;ENST00000262419;ENST00000572904;ENST00000574590;ENST00000638275;ENST00000575318;ENST00000571698;ENST00000638269;ENST00000576248;ENST00000639099;ENST00000639150;ENST00000639356;ENST00000574655;ENST00000638902;ENST00000639375;ENST00000639531;ENST00000639853;ENST00000648792"]
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["chr10","rs2492643","A","G",{"v":0.1019,"d":"0.102"},"10:135020457:135020641:clu_18846_NA",135020457,135020641,"KNDC1","intron_variant","MODIFIER",-906163,{"v":0.734137,"d":"0.734"},{"v":0.146177,"d":"0.146"},{"v":4.38939E-3,"d":"4.39E-03"},{"v":0.049853008,"d":"4.99E-02"},"ENST00000304613;ENST00000682119;ENST00000682309;ENST00000684127;ENST00000683920;ENST00000684081;ENST00000684244"]
["chr3","rs189808246","T","C",{"v":0.009479,"d":"0.009"},"3:180365031:180365828:clu_37525_NA",180365031,180365828,"CCDC39","downstream_gene_variant","MODIFIER",-63343,{"v":1.49286,"d":"1.493"},{"v":0.299754,"d":"0.300"},{"v":0.00439031,"d":"4.39E-03"},{"v":0.049860903,"d":"4.99E-02"},"ENST00000476379;ENST00000651046;ENST00000651922;ENST00000650641;ENST00000652408;ENST00000650889;ENST00000651818;ENST00000652024;ENST00000651576"]
["chr6","rs149451785","T","TC",{"v":0.1273,"d":"0.127"},"6:87920525:87923049:clu_74340_NA",87920525,87923049,"ZNF292","upstream_gene_variant","MODIFIER",627,{"v":-0.425842,"d":"-0.426"},{"v":0.0719071,"d":"0.072"},{"v":0.00439148,"d":"4.39E-03"},{"v":0.049872204,"d":"4.99E-02"},"ENST00000699914;ENST00000699923;ENST00000369578;ENST00000369577;ENST00000699924;ENST00000518845;ENST00000339907;ENST00000699925;ENST00000699990;ENST00000496806;ENST00000466062;ENST00000699989"]
["chr1","rs150061076","G","A",{"v":0.004762,"d":"0.005"},"1:24980821:24981346:clu_8191_NA",24980821,24981346,"SRRM1","intron_variant","MODIFIER",-983827,{"v":-1.53428,"d":"-1.534"},{"v":0.270412,"d":"0.270"},{"v":0.00439233,"d":"4.39E-03"},{"v":0.049879871,"d":"4.99E-02"},"ENST00000323848;ENST00000374389;ENST00000470243;ENST00000479034;ENST00000705662;ENST00000705663;ENST00000496882;ENST00000596378;ENST00000705681;ENST00000705682"]
["chr5","rs148562206","A","G",{"v":0.004739,"d":"0.005"},"5:155281634:155285038:clu_41593_NA",155281634,155285038,"-","intron_variant","MODIFIER",46849,{"v":1.51991,"d":"1.520"},{"v":0.272164,"d":"0.272"},{"v":0.00439392,"d":"4.39E-03"},{"v":0.049895939,"d":"4.99E-02"},"ENST00000755060"]
["chr7","rs28852509","T","C",{"v":0.3603,"d":"0.360"},"7:100491873:100493680:clu_89849_NA",100491873,100493680,"ACHE","upstream_gene_variant","MODIFIER",13030,{"v":-0.334811,"d":"-0.335"},{"v":0.0690977,"d":"0.069"},{"v":0.00439534,"d":"4.40E-03"},{"v":0.049910077,"d":"4.99E-02"},"ENST00000419336;ENST00000241069;ENST00000411582;ENST00000428317;ENST00000302913;ENST00000412389;ENST00000651875;ENST00000441605;ENST00000445236"]
["chr2","rs79354507","C","T",{"v":0.04614,"d":"0.046"},"2:219786482:219791849:clu_5691_NA",219786482,219791849,"-","upstream_gene_variant","MODIFIER",31037,{"v":0.694128,"d":"0.694"},{"v":0.144319,"d":"0.144"},{"v":0.00439678,"d":"4.40E-03"},{"v":0.049922451,"d":"4.99E-02"},"ENST00000715606;ENST00000798772;ENST00000798773;ENST00000798774;ENST00000419511;ENST00000798771;ENST00000798770;ENST00000798775;ENST00000798776;ENST00000798777;ENST00000687233;ENST00000798918;ENST00000798916;ENST00000798917;ENST00000798919"]
["chr4","rs1380373","G","A",{"v":0.4943,"d":"0.494"},"4:118531115:118556069:clu_65402_NA",118531115,118556069,"-","upstream_gene_variant","MODIFIER",205879,{"v":0.295028,"d":"0.295"},{"v":0.0601829,"d":"0.060"},{"v":0.00439662,"d":"4.40E-03"},{"v":0.049922451,"d":"4.99E-02"},"ENST00000422145;ENST00000626258;ENST00000665403;ENST00000660654;ENST00000665215;ENST00000667741;ENST00000600624;ENST00000668162;ENST00000615833;ENST00000671002;ENST00000717559;ENST00000717610;ENST00000717611;ENST00000717643;ENST00000717644;ENST00000717645;ENST00000717638;ENST00000717642;ENST00000717647"]
["chr19","rs4932720","A","G",{"v":0.4229,"d":"0.423"},"19:23937720:23938227:clu_44816_NA",23937720,23938227,"ZNF681","intron_variant","MODIFIER",-88860,{"v":-0.806175,"d":"-0.806"},{"v":0.170147,"d":"0.170"},{"v":0.00439764,"d":"4.40E-03"},{"v":0.049930228,"d":"4.99E-02"},"ENST00000402377;ENST00000528059;ENST00000531570"]
["chr22","rs76083736","G","A",{"v":0.009479,"d":"0.009"},"22:31478988:31479165:clu_22825_NA",31478988,31479165,"SMTN","upstream_gene_variant","MODIFIER",-321824,{"v":1.32785,"d":"1.328"},{"v":0.248269,"d":"0.248"},{"v":0.00439836,"d":"4.40E-03"},{"v":0.049936414,"d":"4.99E-02"},"ENST00000422839;ENST00000440425;ENST00000426927;ENST00000482444;ENST00000475548;ENST00000333137;ENST00000358743;ENST00000347557;ENST00000489337;ENST00000432777;ENST00000438223;ENST00000497697;ENST00000619644;ENST00000609017"]
["chr10","rs186789270","A","G",{"v":0.01422,"d":"0.014"},"10:96343882:96347986:clu_17535_NA",96343882,96347986,"HELLS","upstream_gene_variant","MODIFIER",-918975,{"v":1.24745,"d":"1.247"},{"v":0.254188,"d":"0.254"},{"v":0.00439897,"d":"4.40E-03"},{"v":0.049941351,"d":"4.99E-02"},"ENST00000419900;ENST00000348459;ENST00000698675;ENST00000371327;ENST00000475263;ENST00000698799;ENST00000630929;ENST00000394045;ENST00000394036;ENST00000371332;ENST00000698800;ENST00000698830;ENST00000432120"]
["chr6","rs144566792","T","C",{"v":0.01914,"d":"0.019"},"6:43141851:43146544:clu_73504_NA",43141851,43146544,"SRF","intron_variant","MODIFIER",-65461,{"v":0.901862,"d":"0.902"},{"v":0.150784,"d":"0.151"},{"v":0.00439939,"d":"4.40E-03"},{"v":0.04994413,"d":"4.99E-02"},"ENST00000265354;ENST00000724405"]
["chr17","rs111321708","C","T",{"v":0.09179,"d":"0.092"},"17:79680536:79681995:clu_71423_NA",79680536,79681995,"SLC25A10;SLC25A10","upstream_gene_variant","MODIFIER",-189244,{"v":0.430199,"d":"0.430"},{"v":0.0820919,"d":"0.082"},{"v":0.00440104,"d":"4.40E-03"},{"v":0.049960472,"d":"5.00E-02"},"ENST00000571730;ENST00000545862;ENST00000574129;ENST00000350690;ENST00000331531;ENST00000574884"]
["chr6","rs77418190","C","T",{"v":0.06602,"d":"0.066"},"6:158919844:158927610:clu_75923_NA",158919844,158927610,"TULP4","intron_variant","MODIFIER",-600494,{"v":-0.471243,"d":"-0.471"},{"v":0.090413,"d":"0.090"},{"v":0.00440118,"d":"4.40E-03"},{"v":0.049960472,"d":"5.00E-02"},"ENST00000367097;ENST00000367094"]
["chr9","rs118014480","A","G",{"v":0.05742,"d":"0.057"},"9:139612163:139616103:clu_32625_NA",139612163,139616103,"FAM69B","intergenic_region","MODIFIER",-794300,{"v":0.529861,"d":"0.530"},{"v":0.0849858,"d":"0.085"},{"v":0.00440186,"d":"4.40E-03"},{"v":0.049964213,"d":"5.00E-02"},"ENST00000371692;ENST00000371691;ENST00000414282"]
["chr18","rs147840664","T","C",{"v":0.02941,"d":"0.029"},"18:47750249:47753768:clu_56193_NA",47750249,47753768,"CCDC11","upstream_gene_variant","MODIFIER",-388656,{"v":0.955002,"d":"0.955"},{"v":0.197919,"d":"0.198"},{"v":0.0044022,"d":"4.40E-03"},{"v":0.049966083,"d":"5.00E-02"},"ENST00000398545"]
["chr11","rs57654248","A","G",{"v":0.04842,"d":"0.048"},"11:13002546:13007587:clu_24757_NA",13002546,13007587,"-","upstream_gene_variant","MODIFIER",3787,{"v":-0.779484,"d":"-0.779"},{"v":0.159299,"d":"0.159"},{"v":0.00440256,"d":"4.40E-03"},{"v":0.04996778,"d":"5.00E-02"},"ENST00000658243;ENST00000527945;ENST00000671253;ENST00000653758;ENST00000662291;ENST00000671577;ENST00000663902;ENST00000653958;ENST00000526388;ENST00000531402;ENST00000504230;ENST00000534477;ENST00000532541;ENST00000529328;ENST00000653981;ENST00000716767"]
["chr13","rs2761843","C","T",{"v":0.2397,"d":"0.240"},"13:51290023:51320869:clu_80319_NA",51290023,51320869,"DLEU1;DLEU7","upstream_gene_variant","MODIFIER",3013,{"v":0.36447,"d":"0.364"},{"v":0.0761987,"d":"0.076"},{"v":0.0044027,"d":"4.40E-03"},{"v":0.04996778,"d":"5.00E-02"},"ENST00000470726;ENST00000650910;ENST00000650996;ENST00000652753;ENST00000668174;ENST00000658634;ENST00000671384;ENST00000651397;ENST00000651265;ENST00000400393"]
["chr12","rs12308923","C","A",{"v":0.009615,"d":"0.010"},"12:123035909:123036005:clu_61331_NA",123035909,123036005,"KNTC1","downstream_gene_variant","MODIFIER",-548933,{"v":-1.73887,"d":"-1.739"},{"v":0.199653,"d":"0.200"},{"v":0.00440308,"d":"4.40E-03"},{"v":0.049970103,"d":"5.00E-02"},"ENST00000450485;ENST00000333479"]
["chr10","rs34956170","G","A",{"v":0.1269,"d":"0.127"},"10:122536396:122566298:clu_18440_NA",122536396,122566298,"-","upstream_gene_variant","MODIFIER",145380,{"v":0.392749,"d":"0.393"},{"v":0.0773827,"d":"0.077"},{"v":0.00440433,"d":"4.40E-03"},{"v":0.049978321,"d":"5.00E-02"},"ENST00000659883;ENST00000665554;ENST00000663713;ENST00000655330;ENST00000667515;ENST00000805133;ENST00000661416;ENST00000598981;ENST00000628194;ENST00000456120;ENST00000451706;ENST00000648536;ENST00000805417;ENST00000630905;ENST00000805418;ENST00000805419;ENST00000805420;ENST00000805421;ENST00000661709"]
["chr16","rs111521816","G","GGC",{"v":0.07927,"d":"0.079"},"16:21907937:21910208:clu_49201_NA",21907937,21910208,"-","upstream_gene_variant","MODIFIER",403280,{"v":0.584346,"d":"0.584"},{"v":0.105447,"d":"0.105"},{"v":0.00440431,"d":"4.40E-03"},{"v":0.049978321,"d":"5.00E-02"},"ENST00000523028"]
["chr19","rs4028679","GGAGA","G",{"v":0.1108,"d":"0.111"},"19:7143101:7152737:clu_43296_NA",7143101,7152737,"INSR","intergenic_region","MODIFIER",-510067,{"v":-1.01623,"d":"-1.016"},{"v":0.174875,"d":"0.175"},{"v":4.40471E-3,"d":"4.40E-03"},{"v":0.049980644,"d":"5.00E-02"},"ENST00000341500;ENST00000302850;ENST00000598216"]
["chr9","rs145033206","T","C",{"v":0.1508,"d":"0.151"},"9:131598384:131599081:clu_32013_NA",131598384,131599081,"CCBL1","upstream_gene_variant","MODIFIER",-534216,{"v":0.460386,"d":"0.460"},{"v":0.0942784,"d":"0.094"},{"v":0.00440568,"d":"4.41E-03"},{"v":0.049989661,"d":"5.00E-02"},"ENST00000651925;ENST00000302586;ENST00000462722;ENST00000320665;ENST00000483599;ENST00000436267;ENST00000451800"]
[]
["Chr:The chromosome where the SNP is located."]
["SNP:Unique identifier of the SNP, typically in rs format (e.g., rs12345)."]
["REF:Reference allele (nucleotide) in the genome, representing the non-variant allele."]
["ALT:Alternative allele (nucleotide) that differs from the reference allele."]
["MAF:Minor Allele Frequency, the frequency of the alternative allele in the population. Higher MAF indicates common variants, while lower MAF indicates rare variants."]
["Phenotype_id:Information about the location of the segment where alternative splicing occurs."]
["start:Starting point."]
["end:End site."]
["GENE:Gene associated with the SNP."]
["ANNOT:Annotation indicating the genomic region (e.g., exon, intron, promoter) where the SNP is located."]
["IMPACT:Predicted biological impact of the SNP, classified as HIGH, MODERATE, LOW, or MODIFIER."]
["TSS_distance:Distance from the SNP to the transcription start site (TSS) of the associated gene."]
["BETA:Effect size, indicating the strength and direction of the association between the SNP and phenotype. A positive value indicates a positive correlation."]
["SE:Standard error of the BETA estimate, reflecting the precision of the effect size estimate."]
["Pval_beta:P-value for the association between the SNP and phenotype, indicating statistical significance. A value <0.05 is typically considered significant."]
["FDR:False Discovery Rate, adjusted p-value to control for multiple testing. Typically, FDR < 0.05 indicates significant results."]
["transcript_id:Transcript, the transcriptional product that identifies genes."]

{"sheet":"Supplementary Table 3","index":2,"n_rows":47,"n_cols":13,"rows_kept":47}
["Supplementary Table 3. Full significant MR results after Bonferroni correction and colocalization (P-value< 0.01/5,179 and PPH4＞0.90)."]
["exposure","outcome","method","nsnp","b","se","pval","PPH4","gene","OR","CI_lower","CI_upper","transcript_id"]
["1:98293752:98386440:clu_10717_NA","SCZpgc","Wald ratio",1,{"v":0.234435517960189,"d":"0.234"},{"v":0.0265548496742605,"d":"0.027"},{"v":1.06230799895286E-18,"d":"1.06E-18"},0.999999999996234,"DPYD",{"v":1.26419495193828,"d":"1.264"},{"v":1.2000797496155,"d":"1.200"},{"v":1.33173555925618,"d":"1.332"},"ENST00000370192;ENST00000306031;ENST00000460019;ENST00000646851;ENST00000604863"]
["11:46391100:46392863:clu_25421_NA","SCZpgc","Wald ratio",1,{"v":-0.122330212215722,"d":"-0.122"},{"v":0.0165691726940034,"d":"0.017"},{"v":1.54761309903199e-13,"d":"1.55E-13"},0.999999999722256,"DGKZ",{"v":0.884856129951646,"d":"0.885"},{"v":0.856581517431054,"d":"0.857"},{"v":0.914064049690432,"d":"0.914"},"ENST00000343674;ENST00000454345;ENST00000524448;ENST00000524984;ENST00000318201;ENST00000456247;ENST00000421244;ENST00000527911;ENST00000531879;ENST00000533376;ENST00000528173;ENST00000528615;ENST00000532868"]
["12:110814021:110819557:clu_60723_NA","SCZpgc","Wald ratio",1,{"v":-0.102269712991773,"d":"-0.102"},{"v":0.0145636959423925,"d":"0.015"},{"v":2.18344983554598e-12,"d":"2.18E-12"},0.99833714416733,"ANAPC7",{"v":0.902786025709371,"d":"0.903"},{"v":0.877380463336983,"d":"0.877"},{"v":0.928927235416556,"d":"0.929"},"ENST00000455511;ENST00000481473;ENST00000552087;ENST00000486321;ENST00000452721;ENST00000450008;ENST00000471602;ENST00000547199;ENST00000548234"]
["7:2275199:2279053:clu_87287_NA","SCZpgc","Wald ratio",1,{"v":0.0969193011010369,"d":"0.097"},{"v":0.0144172083799223,"d":"0.014"},{"v":1.78665254842678E-11,"d":"1.79E-11"},0.99999996420543,"FTSJ2",{"v":1.10177145828978,"d":"1.102"},{"v":1.07107366721017,"d":"1.071"},{"v":1.13334907155718,"d":"1.133"},"ENST00000651235;ENST00000724666;ENST00000242257;ENST00000467199;ENST00000440306;ENST00000486040;ENST00000407040"]
["19:50168103:50168929:clu_46764_NA","SCZpgc","Wald ratio",1,{"v":0.112914536534201,"d":"0.113"},{"v":0.0172684378666369,"d":"0.017"},{"v":6.20221908759509e-11,"d":"6.20E-11"},0.999999892097263,"BCL2L12;IRF3",{"v":1.11953624941196,"d":"1.120"},{"v":1.08227834555458,"d":"1.082"},{"v":1.15807677285195,"d":"1.158"},"ENST00000377135;ENST00000309877;ENST00000377139;ENST00000593818;ENST00000595034;ENST00000593337;ENST00000596756;ENST00000596765;ENST00000593922;ENST00000594387;ENST00000596822;ENST00000601809;ENST00000600453;ENST00000601373;ENST00000597180;ENST00000597198;ENST00000597636;ENST00000598108;ENST00000598808;ENST00000599144;ENST00000600022;ENST00000599223;ENST00000600911;ENST00000601291;ENST00000441864;ENST00000246785;ENST00000619007"]
["19:50168103:50168892:clu_46764_NA","SCZpgc","Wald ratio",1,{"v":-0.148767773104627,"d":"-0.149"},{"v":0.0227516059957173,"d":"0.023"},{"v":6.20221908759509e-11,"d":"6.20E-11"},0.99998536523368,"BCL2L12;IRF3",{"v":0.861769217653382,"d":"0.862"},{"v":0.824184455092697,"d":"0.824"},{"v":0.90106793437568,"d":"0.901"},"ENST00000377135;ENST00000309877;ENST00000377139;ENST00000593818;ENST00000595034;ENST00000593337;ENST00000596756;ENST00000596765;ENST00000593922;ENST00000594387;ENST00000596822;ENST00000601809;ENST00000600453;ENST00000601373;ENST00000597180;ENST00000597198;ENST00000597636;ENST00000598108;ENST00000598808;ENST00000599144;ENST00000600022;ENST00000599223;ENST00000600911;ENST00000601291;ENST00000441864;ENST00000246785;ENST00000619007"]
["4:176733400:176923460:clu_66358_NA","SCZpgc","Wald ratio",1,{"v":-0.115273240611474,"d":"-0.115"},{"v":0.0178986585733602,"d":"0.018"},{"v":1.19215207426454e-10,"d":"1.19E-10"},0.933562271054536,"GPM6A",{"v":0.891122619748483,"d":"0.891"},{"v":0.86040281366171,"d":"0.860"},{"v":0.922939245221507,"d":"0.923"},"ENST00000280187;ENST00000393658;ENST00000503397;ENST00000502754;ENST00000503563;ENST00000505375;ENST00000506894;ENST00000507540;ENST00000509865;ENST00000512509;ENST00000512610;ENST00000513365;ENST00000513667;ENST00000809043;ENST00000505816"]
["12:123707674:123710835:clu_61410_NA","SCZpgc","Wald ratio",1,{"v":0.087582508752177,"d":"0.088"},{"v":0.0139364848371045,"d":"0.014"},{"v":3.29112659618102e-10,"d":"3.29E-10"},0.999999415015062,"MPHOSPH9",{"v":1.09153232169747,"d":"1.092"},{"v":1.06212009313179,"d":"1.062"},{"v":1.12175903366742,"d":"1.122"},"ENST00000537854;ENST00000539639;ENST00000541076;ENST00000539336;ENST00000541437;ENST00000538169;ENST00000535049;ENST00000545556;ENST00000606320"]
["7:110731560:110737083:clu_90175_NA","SCZpgc","Wald ratio",1,{"v":0.0905010046497559,"d":"0.091"},{"v":0.0150534136643469,"d":"0.015"},{"v":1.83257208519892e-09,"d":"1.83E-09"},0.99999662586398,"LRRN3;IMMP2L",{"v":1.09472260745389,"d":"1.095"},{"v":1.06289499620833,"d":"1.063"},{"v":1.12750327317917,"d":"1.128"},"ENST00000405709;ENST00000331762;ENST00000489381;ENST00000452895;ENST00000450877;ENST00000447215;ENST00000451085;ENST00000422987;ENST00000421101;ENST00000464835;ENST00000308478"]
["15:85742853:85745048:clu_54622_NA","SCZpgc","Wald ratio",1,{"v":0.0445313518965167,"d":"0.045"},{"v":0.00754711285197848,"d":"0.008"},{"v":3.62514418464572e-09,"d":"3.63E-09"},0.999994240595897,"-",{"v":1.04553775578813,"d":"1.046"},{"v":1.03018563144472,"d":"1.030"},{"v":1.06111866193034,"d":"1.061"},"ENST00000648573;ENST00000837463;ENST00000837470;ENST00000558282;ENST00000559989"]
["3:180688943:180693101:clu_37545_NA","SCZpgc","Wald ratio",1,{"v":0.10638363960728,"d":"0.106"},{"v":0.0194771143905911,"d":"0.019"},{"v":4.70849003315458e-08,"d":"4.71E-08"},0.999924561623662,"FXR1",{"v":1.11224849724367,"d":"1.112"},{"v":1.07058849798994,"d":"1.071"},{"v":1.15552961940418,"d":"1.156"},"ENST00000305586;ENST00000357559;ENST00000445140;ENST00000468861;ENST00000472339;ENST00000480918;ENST00000475315;ENST00000482125;ENST00000481383;ENST00000491062;ENST00000698793;ENST00000698794"]
["19:19390169:19390994:clu_44640_NA","SCZpgc","Wald ratio",1,{"v":0.201987861473558,"d":"0.202"},{"v":0.0372522006095231,"d":"0.037"},{"v":5.88789881844215e-08,"d":"5.89E-08"},0.999922732314465,"SUGP1",{"v":1.22383315249011,"d":"1.224"},{"v":1.13766003070187,"d":"1.138"},{"v":1.31653353788816,"d":"1.317"},"ENST00000589144;ENST00000247001;ENST00000591007;ENST00000588731;ENST00000587119;ENST00000592188"]
["22:39411756:39413978:clu_23268_NA","SCZpgc","Wald ratio",1,{"v":-0.139039768914989,"d":"-0.139"},{"v":0.0258252054004709,"d":"0.026"},{"v":7.28977073482669e-08,"d":"7.29E-08"},0.997409390582155,"APOBEC3C;APOBEC3D",{"v":0.870193421121919,"d":"0.870"},{"v":0.827242687705264,"d":"0.827"},{"v":0.915374171833917,"d":"0.915"},"ENST00000361441;ENST00000428892;ENST00000381568"]
["17:44172067:44248221:clu_69467_NA","SCZpgc","Wald ratio",1,{"v":0.0293203338033288,"d":"0.029"},{"v":0.00558940249287351,"d":"0.006"},{"v":1.55689286024162E-7,"d":"1.56E-07"},0.999799135105542,"KANSL1",{"v":1.02975440679292,"d":"1.030"},{"v":1.01853478056872,"d":"1.019"},{"v":1.04109762232895,"d":"1.041"},"ENST00000432791;ENST00000262419;ENST00000572904;ENST00000574590;ENST00000638275;ENST00000575318;ENST00000571698;ENST00000577114;ENST00000638269;ENST00000576248;ENST00000639099;ENST00000639150;ENST00000639356;ENST00000574655;ENST00000638902;ENST00000639375;ENST00000639531;ENST00000639853;ENST00000648792;ENST00000516889"]
["17:44230332:44248221:clu_69467_NA","SCZpgc","Wald ratio",1,{"v":-0.0360164720047744,"d":"-0.036"},{"v":0.00686590267895039,"d":"0.007"},{"v":1.55689286024162E-7,"d":"1.56E-07"},0.999799135105542,"KANSL1",{"v":0.964624404054469,"d":"0.965"},{"v":0.951730244220166,"d":"0.952"},{"v":0.977693255571465,"d":"0.978"},"ENST00000432791;ENST00000262419;ENST00000572904;ENST00000574590;ENST00000638275;ENST00000575318;ENST00000571698;ENST00000638269;ENST00000576248;ENST00000639099;ENST00000639150;ENST00000639356;ENST00000574655;ENST00000638902;ENST00000639375;ENST00000639531;ENST00000639853;ENST00000648792"]
["3:17255862:17279655:clu_33562_NA","SCZpgc","Wald ratio",1,{"v":-0.140971473219655,"d":"-0.141"},{"v":0.0271322181056098,"d":"0.027"},{"v":2.03926381245947E-7,"d":"2.04E-07"},0.999675071819123,"TBC1D5",{"v":0.868514087254876,"d":"0.869"},{"v":0.823533853675526,"d":"0.824"},{"v":0.915951076441568,"d":"0.916"},"ENST00000253692;ENST00000429383;ENST00000414318;ENST00000429924;ENST00000446818;ENST00000696125"]
["1:173579354:173580248:clu_13063_NA","SCZpgc","Wald ratio",1,{"v":-0.0740777996534214,"d":"-0.074"},{"v":0.0143788813448176,"d":"0.014"},{"v":2.57933152987997E-7,"d":"2.58E-07"},0.999722759847568,"ANKRD45",{"v":0.928599446315817,"d":"0.929"},{"v":0.902794426987203,"d":"0.903"},{"v":0.955142063266485,"d":"0.955"},"ENST00000431459;ENST00000648193;ENST00000333279"]
["2:37475569:37497730:clu_1140_NA","SCZpgc","Wald ratio",1,{"v":0.0800614223642407,"d":"0.080"},{"v":0.0157146614482963,"d":"0.016"},{"v":3.4930134975903e-07,"d":"3.49E-07"},0.999498802915129,"NDUFAF7;PRKD3",{"v":1.08335360777131,"d":"1.083"},{"v":1.05049416409232,"d":"1.050"},{"v":1.11724089441774,"d":"1.117"},"ENST00000002125;ENST00000474154;ENST00000336237;ENST00000441905;ENST00000379066;ENST00000234179;ENST00000469275;ENST00000452104;ENST00000443977;ENST00000494667"]
["2:37475569:37480229:clu_1140_NA","SCZpgc","Wald ratio",1,{"v":-0.0411005627793008,"d":"-0.041"},{"v":0.00806732394126988,"d":"0.008"},{"v":3.49301349759031E-7,"d":"3.49E-07"},0.99949880319648,"NDUFAF7;PRKD3",{"v":0.95973261171599,"d":"0.960"},{"v":0.944676708238987,"d":"0.945"},{"v":0.975028470542301,"d":"0.975"},"ENST00000002125;ENST00000474154;ENST00000336237;ENST00000441905;ENST00000379066;ENST00000234179"]
["12:124429287:124430251:clu_61483_NA","SCZpgc","Wald ratio",1,{"v":0.047609494430838,"d":"0.048"},{"v":0.00943980890543364,"d":"0.009"},{"v":4.57138793577272E-7,"d":"4.57E-07"},0.999330786476603,"CCDC92",{"v":1.04876102832658,"d":"1.049"},{"v":1.02953523162729,"d":"1.030"},{"v":1.06834585233001,"d":"1.068"},"ENST00000238156;ENST00000545135;ENST00000545891;ENST00000539761;ENST00000535556;ENST00000539551;ENST00000545037"]
["12:124429287:124457076:clu_61483_NA","SCZpgc","Wald ratio",1,{"v":-0.112118514126725,"d":"-0.112"},{"v":0.0222303841023758,"d":"0.022"},{"v":4.57138793577275e-07,"d":"4.57E-07"},0.999329450179044,"CCDC92;ZNF664",{"v":0.893938306904371,"d":"0.894"},{"v":0.85582439752158,"d":"0.856"},{"v":0.933749608991374,"d":"0.934"},"ENST00000238156;ENST00000545135;ENST00000545891;ENST00000539761;ENST00000535556;ENST00000539551;ENST00000545037;ENST00000602347;ENST00000602474;ENST00000602988;ENST00000602601;ENST00000602741;ENST00000602558;ENST00000537532"]
["5:153414527:153417853:clu_41555_NA","SCZpgc","Wald ratio",1,{"v":-0.134972123028021,"d":"-0.135"},{"v":0.0268709259600318,"d":"0.027"},{"v":5.08758507829252e-07,"d":"5.09E-07"},0.999159509103497,"FAM114A2",{"v":0.873740268581519,"d":"0.874"},{"v":0.828913776826194,"d":"0.829"},{"v":0.920990913993433,"d":"0.921"},"ENST00000351797;ENST00000522858;ENST00000517605;ENST00000517803;ENST00000518102;ENST00000518900;ENST00000519808;ENST00000520313;ENST00000520667;ENST00000521031;ENST00000522395;ENST00000522634;ENST00000523705;ENST00000524246"]
["4:118531115:118556069:clu_65402_NA","SCZpgc","Wald ratio",1,{"v":-0.147771308886201,"d":"-0.148"},{"v":0.0294887264937565,"d":"0.029"},{"v":5.41164271364001e-07,"d":"5.41E-07"},0.997601876444195,"-",{"v":0.862628367828428,"d":"0.863"},{"v":0.814183740669195,"d":"0.814"},{"v":0.913955491632298,"d":"0.914"},"ENST00000422145;ENST00000626258;ENST00000665403;ENST00000660654;ENST00000665215;ENST00000667741;ENST00000600624;ENST00000668162;ENST00000615833;ENST00000671002;ENST00000717559;ENST00000717610;ENST00000717611;ENST00000717643;ENST00000717644;ENST00000717645;ENST00000717638;ENST00000717642;ENST00000717647"]
["22:50315409:50316260:clu_23811_NA","SCZpgc","Wald ratio",1,{"v":0.0906645354479855,"d":"0.091"},{"v":0.0181665996030513,"d":"0.018"},{"v":6.0152526578275e-07,"d":"6.02E-07"},0.999243495432693,"CRELD2",{"v":1.09490164295424,"d":"1.095"},{"v":1.05660189604708,"d":"1.057"},{"v":1.13458968058721,"d":"1.135"},"ENST00000450207;ENST00000328268;ENST00000404488;ENST00000483652;ENST00000403427;ENST00000407217;ENST00000482956;ENST00000498354;ENST00000462253;ENST00000444954"]
["22:50316091:50316260:clu_23811_NA","SCZpgc","Wald ratio",1,{"v":-0.09897060342855,"d":"-0.099"},{"v":0.0198308998780492,"d":"0.020"},{"v":6.01525265782753e-07,"d":"6.02E-07"},0.999243495571495,"CRELD2",{"v":0.905769334145137,"d":"0.906"},{"v":0.871238804263635,"d":"0.871"},{"v":0.941668441147013,"d":"0.942"},"ENST00000450207;ENST00000328268;ENST00000404488;ENST00000483652;ENST00000403427;ENST00000407217;ENST00000482956;ENST00000462253;ENST00000444954"]
["2:58449177:58456949:clu_1657_NA","SCZpgc","Wald ratio",1,{"v":0.0387965725574762,"d":"0.039"},{"v":0.00784472775592757,"d":"0.008"},{"v":7.59252420387179e-07,"d":"7.59E-07"},0.999288783964577,"-",{"v":1.03955898731267,"d":"1.040"},{"v":1.02369732938748,"d":"1.024"},{"v":1.05566641338133,"d":"1.056"},"ENST00000696318;ENST00000696358;ENST00000696320;ENST00000696338;ENST00000417361;ENST00000427708;ENST00000696305;ENST00000449070;ENST00000446381;ENST00000470506;ENST00000696374;ENST00000696411;ENST00000696361;ENST00000696373;ENST00000696307;ENST00000696394;ENST00000696395;ENST00000696396;ENST00000696341;ENST00000696343;ENST00000696326;ENST00000696340;ENST00000696342;ENST00000696325;ENST00000696306;ENST00000696314;ENST00000696315;ENST00000696345;ENST00000696360;ENST00000696397;ENST00000696398;ENST00000696399;ENST00000696344;ENST00000696362;ENST00000696378;ENST00000696316;ENST00000233741;ENST00000403295;ENST00000696364;ENST00000402135;ENST00000403676;ENST00000696319;ENST00000696415;ENST00000696416;ENST00000696321;ENST00000481670;ENST00000696400;ENST00000696317;ENST00000696403;ENST00000696308;ENST00000696324;ENST00000696404;ENST00000696410;ENST00000696409;ENST00000696371;ENST00000696472;ENST00000696457;ENST00000696458;ENST00000696473;ENST00000696495;ENST00000696509;ENST00000696459;ENST00000696496;ENST00000696438;ENST00000696417;ENST00000696569;ENST00000696377;ENST00000696595;ENST00000696347;ENST00000696478;ENST00000696549;ENST00000696550;ENST00000696476;ENST00000696531;ENST00000696570;ENST00000696380;ENST00000696460;ENST00000696530;ENST00000696346;ENST00000696379;ENST00000696477;ENST00000696511;ENST00000696598;ENST00000696418;ENST00000696461;ENST00000696542;ENST00000696467;ENST00000696493;ENST00000696435;ENST00000696499;ENST00000696434;ENST00000696492;ENST00000696508;ENST00000696454;ENST00000696433;ENST00000696544;ENST00000696594;ENST00000696597;ENST00000696551;ENST00000696596;ENST00000696635;ENST00000696621;ENST00000696620;ENST00000696565;ENST00000696545;ENST00000696543;ENST00000696548;ENST00000696564;ENST00000696634;ENST00000696546;ENST00000696547;ENST00000696566;ENST00000696622;ENST00000696455;ENST00000696468;ENST00000696527;ENST00000696469;ENST00000696528;ENST00000696510;ENST00000696567;ENST00000696623;ENST00000696624;ENST00000696625"]
["13:44449063:44453554:clu_80110_NA","SCZpgc","Wald ratio",1,{"v":0.0926472085294839,"d":"0.093"},{"v":0.0187440213035497,"d":"0.019"},{"v":7.70240748014877e-07,"d":"7.70E-07"},0.99877065927487,"LACC1;CCDC122",{"v":1.09707462841667,"d":"1.097"},{"v":1.0575013692902,"d":"1.058"},{"v":1.13812877719811,"d":"1.138"},"ENST00000444614;ENST00000476570;ENST00000611737;ENST00000613918;ENST00000441843"]
["13:44453870:44454052:clu_80109_NA","SCZpgc","Wald ratio",1,{"v":0.0906743037795556,"d":"0.091"},{"v":0.0183448709216927,"d":"0.018"},{"v":7.70240748014877e-07,"d":"7.70E-07"},0.998834972727111,"LACC1",{"v":1.09491233836876,"d":"1.095"},{"v":1.05624308906736,"d":"1.056"},{"v":1.13499727583609,"d":"1.135"},"ENST00000444614;ENST00000441843;ENST00000425906;ENST00000325686"]
["13:44449063:44453767:clu_80110_NA","SCZpgc","Wald ratio",1,{"v":-0.091136667954974,"d":"-0.091"},{"v":0.0184384146354386,"d":"0.018"},{"v":7.7024074801488e-07,"d":"7.70E-07"},0.998799280695635,"LACC1;CCDC122",{"v":0.912892939162205,"d":"0.913"},{"v":0.880490658301548,"d":"0.880"},{"v":0.946487632225166,"d":"0.946"},"ENST00000444614;ENST00000476570;ENST00000611737;ENST00000613918;ENST00000441843;ENST00000425906"]
["1:243727150:243736228:clu_15085_NA","SCZpgc","Wald ratio",1,{"v":-0.190784690182894,"d":"-0.191"},{"v":0.0391340200422088,"d":"0.039"},{"v":1.08719158899675E-6,"d":"1.09E-06"},0.99872036238419,"AKT3",{"v":0.826310481758087,"d":"0.826"},{"v":0.765299996709699,"d":"0.765"},{"v":0.892184784004754,"d":"0.892"},"ENST00000336199;ENST00000366540;ENST00000263826;ENST00000366539;ENST00000680118;ENST00000673466;ENST00000680056;ENST00000681794;ENST00000679831;ENST00000672460;ENST00000672578"]
["8:130915596:130983189:clu_86396_NA","SCZpgc","Wald ratio",1,{"v":0.0775987338133305,"d":"0.078"},{"v":0.0161494211267841,"d":"0.016"},{"v":1.54714855936594e-06,"d":"1.55E-06"},0.997725940805111,"FAM49B",{"v":1.08068892773012,"d":"1.081"},{"v":1.04701773268287,"d":"1.047"},{"v":1.11544295962006,"d":"1.115"},"ENST00000401979;ENST00000519142;ENST00000517672;ENST00000518167;ENST00000518285;ENST00000518344;ENST00000519070;ENST00000519110;ENST00000517654;ENST00000518283;ENST00000518879;ENST00000519020;ENST00000519824;ENST00000520254;ENST00000694912;ENST00000519540;ENST00000703342;ENST00000699094;ENST00000520204;ENST00000522746;ENST00000523509;ENST00000523288;ENST00000522250;ENST00000521223;ENST00000523993;ENST00000522361;ENST00000522702;ENST00000522941;ENST00000523514;ENST00000520146;ENST00000665358;ENST00000658834;ENST00000654339"]
[]
["exposure:Information about the location of the segment where alternative splicing occurs."]
["outcome:PGC of schizophrenia."]
["method:The method MR estimate."]
["nsnp:The number of SNPS available for each splicing segment after data processing."]
["b:The beta effect size."]
["se:Stand error."]
["pval: P-value of the splicing segment estimated by MR analysis."]
["PPH4: Schizophrenia and splicing segments have the same causal variation posterior probability.."]
["gene:Splicing site corresponding gene."]
["OR:The odds ratio associated with the effect of the exposure on the outcome, often used for binary outcomes."]
["CI_lower:The lower bound of the confidence interval for the OR, indicating the range of plausible values for the effect size."]
["CI_upper:The upper bound of the confidence interval for the OR, indicating the range of plausible values for the effect size."]
["transcript_id:Transcript, the transcriptional product that identifies genes."]

{"sheet":"Supplementary Table 4","index":3,"n_rows":17,"n_cols":4,"rows_kept":17}
["Supplementary Table 4. Difference splicing analyses of MR-identified risk genes (P-value ＜ 1×10-3)."]
["Splice site","Gene","Wilcoxon_Pvalue","novel"]
["chr8:130915596-130983189","FAM49B",{"v":1.65e-14,"d":"1.65E-14"},"yes"]
["chr22:50315409-50316260","CRELD2",{"v":5.11e-07,"d":"5.11E-07"},"yes"]
["chr13:44449063-44453767","LACC1;CCDC122",{"v":3.8e-05,"d":"3.80E-05"},"no"]
["chr7:2275199-2279053","FTSJ2",{"v":5.15e-05,"d":"5.15E-05"},"yes"]
["chr1:98293752-98386440","DPYD",{"v":5.25e-05,"d":"5.25E-05"},"no"]
["chr12:110814021-110819557","ANAPC7",{"v":6.15e-05,"d":"6.15E-05"},"no"]
["chr11:46391100-46392863","DGKZ",{"v":8.91e-05,"d":"8.91E-05"},"no"]
["chr17:44172067-44248221","-",{"v":0.000262,"d":"2.62E-04"},"no"]
["chr7:110731560-110737083","LRRN3;IMMP2L",{"v":0.000378,"d":"3.78E-04"},"no"]
["chr2:37475569-37480229","NDUFAF7;PRKD3",{"v":0.000393,"d":"3.93E-04"},"no"]
[]
["Splice site:Information about the segment in which alternative splicing occurs, including chromosomes, as well as start and end."]
["Gene:All the genes in the splice site"]
["Wilcoxon_Pvalue:P-values calculated by Wilcoxon rank sum test in differential splicing analysis."]
["novel:Genes not previously reported in SCZ GWAS studies (PGC3)."]

{"sheet":"Supplementary Table 5","index":4,"n_rows":40,"n_cols":7,"rows_kept":40}
["Supplementary Table 5.Single-cell analysis of the distribution of different genes in different cell types."]
["gene","p_val","avg_log2FC","pct.1","pct.2","p_val_adj","cluster"]
["DPYD","-",{"v":2.59967448582406,"d":"2.600"},0.731,0.277,"-","oligodendrocytes"]
["CCDC122",{"v":3.08847961459584E-193,"d":"3.09E-193"},{"v":3.11307366727616,"d":"3.113"},0.138,{"v":0.03,"d":"0.030"},{"v":9.70832682052057E-189,"d":"9.71E-189"},"oligodendrocytes"]
["TBC1D5",{"v":2.0638589051636e-33,"d":"2.06E-33"},{"v":0.56591357735515,"d":"0.566"},0.461,0.468,{"v":6.48753408249126e-29,"d":"6.49E-29"},"oligodendrocytes"]
["GPM6A","-",{"v":0.351091692446459,"d":"0.351"},0.822,0.352,"-","excitatory neurons"]
["DGKZ","-",{"v":1.9937489279078,"d":"1.994"},0.419,0.095,"-","excitatory neurons"]
["CCDC92",{"v":3.95915206879131e-237,"d":"3.96E-237"},{"v":1.14647059357537,"d":"1.146"},0.329,{"v":0.12,"d":"0.120"},{"v":1.24451986130386E-232,"d":"1.24E-232"},"excitatory neurons"]
["LRRN3",{"v":9.77570671938756e-171,"d":"9.78E-171"},{"v":1.75117118940286,"d":"1.751"},{"v":0.17,"d":"0.170"},0.049,{"v":3.07289565017229e-166,"d":"3.07E-166"},"excitatory neurons"]
["MPHOSPH9",{"v":9.64492555846691e-52,"d":"9.64E-52"},{"v":0.374115126154469,"d":"0.374"},0.215,0.121,{"v":3.03178590004849E-47,"d":"3.03E-47"},"excitatory neurons"]
["FAM49B",{"v":1.32012015797542E-49,"d":"1.32E-49"},{"v":0.279437957552656,"d":"0.279"},{"v":0.49,"d":"0.490"},0.305,{"v":4.14966570457993e-45,"d":"4.15E-45"},"inhibitory neurons"]
["MPHOSPH9",{"v":1.72351214343065e-30,"d":"1.72E-30"},{"v":0.517989023286999,"d":"0.518"},0.227,0.133,{"v":5.41768807165989e-26,"d":"5.42E-26"},"inhibitory neurons"]
["IMMP2L",{"v":4.80988242357723e-25,"d":"4.81E-25"},{"v":0.16795646376575,"d":"0.168"},0.462,0.322,{"v":1.51193844102727e-20,"d":"1.51E-20"},"inhibitory neurons"]
["LRRN3",{"v":1.49043107589752e-14,"d":"1.49E-14"},{"v":0.607309975377559,"d":"0.607"},0.118,0.072,{"v":4.68502104397627e-10,"d":"4.69E-10"},"inhibitory neurons"]
["CCDC92",{"v":5.52800447342648e-12,"d":"5.53E-12"},{"v":0.248557958740955,"d":"0.249"},0.225,0.161,{"v":1.73767292617688E-7,"d":"1.74E-07"},"inhibitory neurons"]
["GPM6A","-",{"v":3.44088157644026,"d":"3.441"},0.988,0.418,"-","astrocytes"]
["AKT3",{"v":8.0910581624129e-37,"d":"8.09E-37"},{"v":0.355001023100138,"d":"0.355"},0.718,0.513,{"v":2.54334322277287e-32,"d":"2.54E-32"},"astrocytes"]
["LRRN3",{"v":3.32070052050977e-27,"d":"3.32E-27"},{"v":0.95976900609382,"d":"0.960"},0.147,0.071,{"v":1.04382900161704E-22,"d":"1.04E-22"},"astrocytes"]
["DGKZ",{"v":3.19838180359939e-15,"d":"3.20E-15"},{"v":0.454268315268158,"d":"0.454"},0.246,0.163,{"v":1.00537933614343e-10,"d":"1.01E-10"},"astrocytes"]
["MPHOSPH9",{"v":2.05107476835045e-12,"d":"2.05E-12"},{"v":0.2525238705343,"d":"0.253"},0.209,0.138,{"v":6.4473484268328E-8,"d":"6.45E-08"},"astrocytes"]
["GPM6A",{"v":1.10278764122733E-234,"d":"1.10E-234"},{"v":0.823015126937172,"d":"0.823"},0.915,0.434,{"v":3.466502671434e-230,"d":"3.47E-230"},"oligodendrocyte progenitor cells"]
["AKT3",{"v":6.67854456605617e-55,"d":"6.68E-55"},{"v":0.631254546878005,"d":"0.631"},0.755,0.515,{"v":2.0993336988941e-50,"d":"2.10E-50"},"oligodendrocyte progenitor cells"]
["LRRN3",{"v":5.48667571651323E-35,"d":"5.49E-35"},{"v":1.10043187080375,"d":"1.100"},0.173,0.072,{"v":1.72468164472877E-30,"d":"1.72E-30"},"oligodendrocyte progenitor cells"]
["FAM49B",{"v":5.98851524626512e-20,"d":"5.99E-20"},{"v":0.20242775109586,"d":"0.202"},0.479,0.316,{"v":1.88242988251098e-15,"d":"1.88E-15"},"oligodendrocyte progenitor cells"]
["FAM49B",{"v":1.45431369355403E-205,"d":"1.45E-205"},{"v":2.40926704355141,"d":"2.409"},0.628,{"v":0.31,"d":"0.310"},{"v":4.57148966431773e-201,"d":"4.57E-201"},"microglia"]
["PRKD3",{"v":8.46838720522714e-100,"d":"8.47E-100"},{"v":3.16941139097793,"d":"3.169"},0.154,0.031,{"v":2.6619528340911e-95,"d":"2.66E-95"},"microglia"]
["TBC1D5",{"v":7.99955250481024e-35,"d":"8.00E-35"},{"v":1.03913209721292,"d":"1.039"},0.536,0.461,{"v":2.51457933436205e-30,"d":"2.51E-30"},"microglia"]
["KANSL1",{"v":4.41607292884936e-18,"d":"4.42E-18"},0.953755911794447,0.451,0.412,{"v":1.38814836445451E-13,"d":"1.39E-13"},"microglia"]
["IMMP2L",{"v":3.06494741015989e-12,"d":"3.06E-12"},{"v":1.05062368734223,"d":"1.051"},0.374,0.335,{"v":9.63435568909658e-08,"d":"9.63E-08"},"microglia"]
["AKT3",{"v":0.0088619078222815,"d":"8.86E-03"},{"v":0.175974538126261,"d":"0.176"},0.401,0.534,{"v":1,"d":"1.00E+00"},"microglia"]
["PRKD3",{"v":2.78045822311337e-22,"d":"2.78E-22"},{"v":2.38427176877647,"d":"2.384"},0.183,0.035,{"v":8.74009237853458e-18,"d":"8.74E-18"},"excitatory neurons"]
["IMMP2L",{"v":4.53793567446553e-10,"d":"4.54E-10"},{"v":1.33844671428736,"d":"1.338"},{"v":0.51,"d":"0.510"},0.336,{"v":1.4264546999115E-5,"d":"1.43E-05"},"excitatory neurons"]
[]
["gene:Gene name."]
["p_val:Original p value."]
["avg_log2FC:The log2 fold change is used to measure the average multiple of difference in gene expression levels between two groups of samples."]
["pct.1:The percentage of cells with the expression of this gene detected in the first group of samples."]
["pct.2:The percentage of cells with the expression of this gene detected in the second group of samples."]
["p_val_adj:The corrected p value."]
["cluster:The clustering group of the cell type to which the gene belongs."]

{"sheet":"Supplementary Table 6","index":5,"n_rows":14,"n_cols":7,"rows_kept":14}
["Supplementary Table 6.Summary of the results of six potential risk genes with consistent splicing regulatory effects."]
["Gene","Splice site","MR_pval","PPH4","OR","Wilcoxon_Pvalue","cluster"]
["DPYD","chr1:98293752-98386440",{"v":1.06230799895286E-18,"d":"1.06E-18"},{"v":0.999999999996234,"d":"1.000"},1.26419495193828,{"v":5.25e-05,"d":"5.25E-05"},"oligodendrocytes"]
["LACC1;CCDC122","chr13:44449063-44453767",{"v":7.7024074801488e-07,"d":"7.70E-07"},{"v":0.998799280695635,"d":"0.999"},0.912892939162205,{"v":3.8e-05,"d":"3.80E-05"},"oligodendrocytes"]
["ANAPC7","chr12:110814021-110819557",{"v":2.18344983554598e-12,"d":"2.18E-12"},{"v":0.99833714416733,"d":"0.998"},0.902786025709371,{"v":6.15e-05,"d":"6.15E-05"},"-"]
["DGKZ","chr11:46391100-46392863",{"v":1.54761309903199e-13,"d":"1.55E-13"},{"v":0.999999999722256,"d":"1.000"},0.884856129951646,{"v":8.91e-05,"d":"8.91E-05"},"excitatory neurons,astrocytes"]
[]
["Gene:All the genes in the splice site"]
["Splice site:Information about the segment in which alternative splicing occurs, including chromosomes, as well as start and end."]
["MR_pval:P-value of the splicing segment estimated by MR analysis."]
["PPH4: Schizophrenia and splicing segments have the same causal variation posterior probability."]
["OR:The odds ratio associated with the effect of the exposure on the outcome, often used for binary outcomes."]
["Wilcoxon_Pvalue:P-values calculated by Wilcoxon rank sum test in differential splicing analysis."]
["cluster:The clustering group of the cell type to which the gene belongs."]

{"sheet":"Supplementary Table 7","index":6,"n_rows":29,"n_cols":12,"rows_kept":29}
["Supplementary Table 7.Full significant GTEx-MR results after Bonferroni correction and colocalization (P-value< 0.01/3,764 and PPH4＞0.90)."]
["exposure","outcome","method","nsnp","b","se","pval","PPH4","gene","OR","CI_lower","CI_upper"]
["chr1:173610215:173624787:clu_2153_-:ENSG00000183831.7","SCZpgc","Wald ratio",1,{"v":-0.0423827432913291,"d":"-0.042"},{"v":0.00822670813259958,"d":"0.008"},{"v":2.57933152987998E-7,"d":"2.58E-07"},0.999722759847568,"ANKRD45",{"v":0.958502849821333,"d":"0.959"},{"v":0.943171552128392,"d":"0.943"},{"v":0.974083358475333,"d":"0.974"}]
["chr1:7771385:7773442:clu_2945_+:ENSG00000049245.13","SCZpgc","Wald ratio",1,{"v":-0.12945381442387,"d":"-0.129"},{"v":0.0265942290522957,"d":"0.027"},{"v":1.128812341917e-06,"d":"1.13E-06"},0.921887010671133,"VAMP3",{"v":0.878575164979381,"d":"0.879"},{"v":0.833952774633477,"d":"0.834"},{"v":0.925585169805083,"d":"0.926"}]
["chr11:46369550:46371313:clu_9877_+:ENSG00000149091.15","SCZpgc","Wald ratio",1,{"v":0.150705050174503,"d":"0.151"},{"v":0.0203549619683605,"d":"0.020"},{"v":1.32293564878458e-13,"d":"1.32E-13"},0.999999999413525,"DGKZ",{"v":1.16265368300317,"d":"1.163"},{"v":1.11718186757514,"d":"1.117"},{"v":1.20997630362088,"d":"1.210"}]
["chr12:123944740:123945704:clu_12452_-:ENSG00000119242.9","SCZpgc","Wald ratio",1,{"v":-0.0312508785476825,"d":"-0.031"},{"v":0.00623711899338323,"d":"0.006"},{"v":5.42981246690808e-07,"d":"5.43E-07"},0.999210348490127,"CCDC92",{"v":0.969232382959106,"d":"0.969"},{"v":0.957455885307411,"d":"0.957"},{"v":0.981153728952191,"d":"0.981"}]
["chr14:103715979:103728908:clu_16048_+:ENSG00000100711.14","SCZpgc","Wald ratio",1,{"v":0.120709022001733,"d":"0.121"},{"v":0.0198579154989915,"d":"0.020"},{"v":1.21209841937612e-09,"d":"1.21E-09"},0.999997786801907,"ZFYVE21",{"v":1.12829655512423,"d":"1.128"},{"v":1.08522518324922,"d":"1.085"},{"v":1.17307738150125,"d":"1.173"}]
["chr15:43632363:43632717:clu_17260_-:ENSG00000249839.1","SCZpgc","Wald ratio",1,{"v":0.0588757112464159,"d":"0.059"},{"v":0.0105217065995545,"d":"0.011"},{"v":2.19805904283024E-8,"d":"2.20E-08"},0.999966627706585,"CATSPER2;STRC",{"v":1.06064340650058,"d":"1.061"},{"v":1.03899423792375,"d":"1.039"},{"v":1.08274367141939,"d":"1.083"}]
["chr17:46094701:46170855:clu_22523_-:ENSG00000120071.15","SCZpgc","Wald ratio",1,{"v":-0.0372836311260003,"d":"-0.037"},{"v":0.00705897452351922,"d":"0.007"},{"v":1.27966370488676e-07,"d":"1.28E-07"},0.999833737614264,"KANSL1",{"v":0.963402845560262,"d":"0.963"},{"v":0.950165383929717,"d":"0.950"},{"v":0.976824728127819,"d":"0.977"}]
["chr19:49664846:49665672:clu_27233_-:ENSG00000126456.16","SCZpgc","Wald ratio",1,{"v":-0.0870304203799899,"d":"-0.087"},{"v":0.0137420932441445,"d":"0.014"},{"v":2.40241809300396e-10,"d":"2.40E-10"},0.999999073246346,"BCL2L12;IRF3",{"v":0.916649210391717,"d":"0.917"},{"v":0.892289254040055,"d":"0.892"},{"v":0.941674206102273,"d":"0.942"}]
["chr2:37248426:37253086:clu_31594_+:ENSG00000003509.16","SCZpgc","Wald ratio",1,{"v":0.0416455383187431,"d":"0.042"},{"v":0.00817429313875647,"d":"0.008"},{"v":3.4930134975903e-07,"d":"3.49E-07"},0.99949880319648,"NDUFAF7;PRKD3",{"v":1.04252487812895,"d":"1.043"},{"v":1.02595503860585,"d":"1.026"},{"v":1.05936233131102,"d":"1.059"}]
["chr2:58222042:58226728:clu_29873_-:ENSG00000115392.12","SCZpgc","Wald ratio",1,{"v":0.0583714186028014,"d":"0.058"},{"v":0.0119333679698662,"d":"0.012"},{"v":1.00098131046836e-06,"d":"1.00E-06"},0.999072485740438,"FANCL",{"v":1.0601086666772,"d":"1.060"},{"v":1.03560108581331,"d":"1.036"},{"v":1.08519622136308,"d":"1.085"}]
["chr22:49921761:49922612:clu_36917_+:ENSG00000184164.15","SCZpgc","Wald ratio",1,{"v":-0.0460881906991823,"d":"-0.046"},{"v":0.00848189994558781,"d":"0.008"},{"v":5.51940329524468e-08,"d":"5.52E-08"},0.999923626860661,"CRELD2",{"v":0.954957740086178,"d":"0.955"},{"v":0.939213257198136,"d":"0.939"},{"v":0.970966155302168,"d":"0.971"}]
["chr3:19946254:19946919:clu_37162_-:ENSG00000163576.18","SCZpgc","Wald ratio",1,{"v":0.101421416429575,"d":"0.101"},{"v":0.0214301255216436,"d":"0.021"},{"v":2.21600652409154e-06,"d":"2.22E-06"},0.993281630196141,"EFHB",{"v":1.10674294316255,"d":"1.107"},{"v":1.06121913055823,"d":"1.061"},{"v":1.15421962059408,"d":"1.154"}]
["chr6:31270085:31270210:clu_46465_-:ENSG00000204525.18","SCZpgc","Wald ratio",1,{"v":0.031003932166685,"d":"0.031"},{"v":0.0055880691718842,"d":"0.006"},{"v":2.88564536969331E-8,"d":"2.89E-08"},0.999953975493153,"HLA-C",{"v":1.03148955986743,"d":"1.031"},{"v":1.02025369462375,"d":"1.020"},{"v":1.04284916361698,"d":"1.043"}]
["chr6:31651776:31652235:clu_46483_-:ENSG00000204463.14","SCZpgc","Wald ratio",1,{"v":0.092044689419928,"d":"0.092"},{"v":0.0126478569611697,"d":"0.013"},{"v":3.40080859204807e-13,"d":"3.40E-13"},0.999999999258797,"BAG6",{"v":1.09641381908356,"d":"1.096"},{"v":1.06956806539792,"d":"1.070"},{"v":1.12393339102749,"d":"1.124"}]
["chr7:2235564:2239418:clu_49040_-:ENSG00000122687.19","SCZpgc","Wald ratio",1,{"v":-0.0658667065531732,"d":"-0.066"},{"v":0.00998924235438758,"d":"0.010"},{"v":4.28813196526842e-11,"d":"4.29E-11"},0.999999916655891,"FTSJ2",{"v":0.936255652717756,"d":"0.936"},{"v":0.918103066702152,"d":"0.918"},{"v":0.954767148741403,"d":"0.955"}]
["chr7:23698299:23700786:clu_47821_+:ENSG00000188732.11","SCZpgc","Wald ratio",1,{"v":0.0367340801856636,"d":"0.037"},{"v":0.00759341668432578,"d":"0.008"},{"v":1.31401681581611E-6,"d":"1.31E-06"},0.998033701124005,"FAM221A",{"v":1.03741711438884,"d":"1.037"},{"v":1.02209146461294,"d":"1.022"},{"v":1.05297256311052,"d":"1.053"}]
["chr8:142273587:142274781:clu_51045_-:ENSG00000171045.16","SCZpgc","Wald ratio",1,{"v":0.0870933434509634,"d":"0.087"},{"v":0.0138091636354506,"d":"0.014"},{"v":2.8463578607515e-10,"d":"2.85E-10"},0.999999455336108,"TSNARE1",{"v":1.09099851253165,"d":"1.091"},{"v":1.06186562292211,"d":"1.062"},{"v":1.12093067960029,"d":"1.121"}]
[]
["exposure:Information about the location of the segment where alternative splicing occurs."]
["outcome:PGC of schizophrenia."]
["method:The method MR estimate."]
["nsnp:The number of SNPS available for each splicing segment after data processing."]
["b:The beta effect size."]
["se:Stand error."]
["pval: P-value of the splicing segment estimated by MR analysis."]
["PPH4: Schizophrenia and splicing segments have the same causal variation posterior probability.."]
["gene:Splicing site corresponding gene."]