F1_nr F1 F1_p F2_nr F2_NormalGlands F2_p F3_nr F3_Stroma F3_p F4_nr F4 F4_p F5_nr F5_PIN F5_p F6_nr F6_cancer F6_p F7_nr F7 F7_p F8_nr F8_ReactiveStroma F8_p F9_nr F9_ImmuneSignature F9_p F10_nr F10 F10_p 2 Cell cycle 0.000493 Glutamatergic synapse 4.53E-11 1 Focal adhesion 3.99E-40 7 Nucleotide excision repair 0.000000488 Cell cycle 1.16E-11 2 Cell cycle 2.34E-25 2 Basal transcription factors 4.75E-21 Cell adhesion molecules (CAMs) 4.45E-33 6 TNF signaling pathway 0.0000804 2 Graft-versus-host disease 1.39E-32 7 Fanconi anemia pathway 0.00712 Neuroactive ligand-receptor interaction 1.1E-09 2 Regulation of actin cytoskeleton 3.38E-33 8 Basal transcription factors 0.000000616 Basal transcription factors 8.2E-11 3 DNA replication 5.64E-20 6 Cell cycle 9.56E-09 Allograft rejection 2.45E-28 8 Nicotine addiction 0.000146 3 Intestinal immune network for IgA production 6.29E-32 9 DNA replication 0.0139 Nicotine addiction 2.71E-09 3 Leukocyte transendothelial migration 1.97E-32 9 Fanconi anemia pathway 0.0000082 Nucleotide excision repair 0.000000009 4 Fanconi anemia pathway 1.25E-18 10 Thyroid hormone signaling pathway 0.0000257 Cytokine-cytokine receptor interaction 1.53E-26 9 TGF-beta signaling pathway 0.000973 4 Asthma 5.21E-30 12 p53 signaling pathway 0.0245 Circadian entrainment 0.00000014 4 Bacterial invasion of epithelial cells 2.65E-30 10 Nicotine addiction 0.0000364 Fanconi anemia pathway 2.26E-08 5 Homologous recombination 1.41E-15 12 Nucleotide excision repair 0.000134 Autoimmune thyroid disease 1.39E-24 10 Alcoholism 0.00254 5 Allograft rejection 8.13E-26 13 Ribosome biogenesis in eukaryotes 0.0287 Retrograde endocannabinoid signaling 0.0000811 5 Hypertrophic cardiomyopathy (HCM) 1.08E-28 11 Cell cycle 0.0000641 Mismatch repair 0.00000247 6 Staphylococcus aureus infection 3.91E-13 20 Epstein-Barr virus infection 0.0222 Primary immunodeficiency 1.93E-23 11 Cell cycle 0.00254 6 Inflammatory bowel disease (IBD) 1.25E-25 10 Cocaine addiction 0.0000949 6 Proteoglycans in cancer 2.14E-27 14 Alcoholism 0.000685 DNA replication 0.00000601 7 Complement and coagulation cascades 2.06E-12 21 Fanconi anemia pathway 0.0251 Graft-versus-host disease 6.81E-23 12 Pathways in cancer 0.00304 7 Staphylococcus aureus infection 1.3E-24 11 Serotonergic synapse 0.000728 7 ECM-receptor interaction 1.14E-23 15 Ubiquitin mediated proteolysis 0.000867 Ribosome biogenesis in eukaryotes 0.0000318 8 p53 signaling pathway 6.7E-11 23 Pyrimidine metabolism 0.0271 Intestinal immune network for IgA production 3.61E-22 13 Viral carcinogenesis 0.00514 8 Autoimmune thyroid disease 7.17E-22 12 Renin secretion 0.00536 8 Amoebiasis 1.78E-23 17 Neuroactive ligand-receptor interaction 0.00112 Homologous recombination 0.000181 9 Mismatch repair 9.27E-11 25 Homologous recombination 0.0417 Hematopoietic cell lineage 3.72E-21 14 Chronic myeloid leukemia 0.00757 10 Cell adhesion molecules (CAMs) 1.34E-19 13 Cholinergic synapse 0.00583 9 Rap1 signaling pathway 1.93E-23 20 Viral carcinogenesis 0.00249 Wnt signaling pathway 0.0102 10 Progesterone-mediated oocyte maturation 0.000000937 10 Asthma 1.94E-18 16 Colorectal cancer 0.00935 11 Hematopoietic cell lineage 1.24E-18 14 Long-term depression 0.00712 10 Tight junction 1E-22 27 Homologous recombination 0.0288 Herpes simplex infection 0.0294 11 Asthma 0.000025 11 Type I diabetes mellitus 1.85E-16 17 MAPK signaling pathway 0.0115 12 Systemic lupus erythematosus 1.66E-18 15 Melanogenesis 0.00736 11 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 7.14E-22 30 Small cell lung cancer 0.0318 12 HTLV-I infection 0.000605 12 Inflammatory bowel disease (IBD) 2.42E-14 19 ErbB signaling pathway 0.0231 13 Leishmaniasis 1.99E-15 16 Salivary secretion 0.00873 12 Platelet activation 5.68E-19 31 Colorectal cancer 0.0318 13 Intestinal immune network for IgA production 0.00131 13 Staphylococcus aureus infection 2.55E-12 20 Pancreatic cancer 0.027 14 Primary immunodeficiency 4.15E-14 17 Aldosterone synthesis and secretion 0.0103 13 Oxytocin signaling pathway 1.64E-18 32 Signaling pathways regulating pluripotency of stem cells 0.0344 14 Non-homologous end-joining 0.00251 14 Leishmaniasis 6.03E-12 21 Signaling pathways regulating pluripotency of stem cells 0.0432 15 Cytokine-cytokine receptor interaction 1.68E-13 18 Insulin secretion 0.0124 14 Adherens junction 6.44E-17 35 Nicotine addiction 0.0432 16 Nucleotide excision repair 0.00723 15 HTLV-I infection 1.33E-11 22 FoxO signaling pathway 0.0485 16 DNA replication 6.77E-13 20 Gastric acid secretion 0.0136 15 Chemokine signaling pathway 1.03E-16 17 Oocyte meiosis 0.0328 16 Viral myocarditis 1.42E-11 23 Dorso-ventral axis formation 0.0486 17 Type I diabetes mellitus 4.77E-12 21 Long-term potentiation 0.0162 16 Fc gamma R-mediated phagocytosis 4.21E-16 19 Pyrimidine metabolism 0.0483 17 Antigen processing and presentation 1.22E-09 18 Nucleotide excision repair 9.56E-12 22 Morphine addiction 0.0299 17 Endocytosis 1.29E-14 18 Natural killer cell mediated cytotoxicity 2.15E-09 19 Cell cycle 1.62E-11 23 GABAergic synapse 0.0302 18 PI3K-Akt signaling pathway 1.48E-14 19 Cell cycle 6.64E-09 20 Basal transcription factors 5.97E-11 24 Amphetamine addiction 0.0349 19 Pathogenic Escherichia coli infection 4.33E-14 20 Chemokine signaling pathway 0.00000223 21 Ribosome biogenesis in eukaryotes 7.74E-11 25 cAMP signaling pathway 0.0365 20 Shigellosis 6.05E-14 21 Malaria 0.0000029 22 RNA polymerase 1.14E-10 21 Salmonella infection 1.54E-13 22 Phagosome 0.0000137 23 Mismatch repair 5.01E-10 22 Ras signaling pathway 1.59E-12 23 Herpes simplex infection 0.0000259 25 Pyrimidine metabolism 1.09E-08 23 Gap junction 6.37E-12 24 Rheumatoid arthritis 0.0000375 26 Transcriptional misregulation in cancer 1.78E-08 25 Adrenergic signaling in cardiomyocytes 3.08E-11 25 Tuberculosis 0.0000629 27 NF-kappa B signaling pathway 0.000000156 26 Synaptic vesicle cycle 4.27E-11 26 B cell receptor signaling pathway 0.0000996 30 Cytosolic DNA-sensing pathway 0.000000424 27 Vascular smooth muscle contraction 1.37E-10 28 Endocytosis 0.000191 32 Fanconi anemia pathway 0.00000236 28 VEGF signaling pathway 3.4E-10 29 Osteoclast differentiation 0.000201 33 Herpes simplex infection 0.00000368 29 Gastric acid secretion 2.31E-09 30 Fc gamma R-mediated phagocytosis 0.000644 36 Homologous recombination 0.0000152 30 Insulin signaling pathway 2.57E-09 31 DNA replication 0.00179 39 Purine metabolism 0.000439 31 Natural killer cell mediated cytotoxicity 2.77E-09 32 Progesterone-mediated oocyte maturation 0.00246 40 Antigen processing and presentation 0.000532 32 Cytokine-cytokine receptor interaction 6.29E-09 33 NF-kappa B signaling pathway 0.00269 42 Alcoholism 0.00179 33 cAMP signaling pathway 1.38E-08 34 Neuroactive ligand-receptor interaction 0.00277 44 HTLV-I infection 0.00269 34 GABAergic synapse 2.15E-08 35 Nicotine addiction 0.00774 46 Epstein-Barr virus infection 0.00498 35 MAPK signaling pathway 5.27E-08 36 Fanconi anemia pathway 0.0127 55 Toxoplasmosis 0.032 36 T cell receptor signaling pathway 0.000000096 38 Epstein-Barr virus infection 0.0191 57 Malaria 0.0336 37 Toxoplasmosis 0.000000196 39 Oocyte meiosis 0.0198 38 Phagosome 0.000000248 40 Viral carcinogenesis 0.0242 39 Sphingolipid signaling pathway 0.000000313 42 T cell receptor signaling pathway 0.0263 40 Circadian entrainment 0.000000336 43 Hepatitis B 0.0472 41 Pertussis 0.000000708 44 Influenza A 0.049 42 Estrogen signaling pathway 0.00000118 43 Epithelial cell signaling in Helicobacter pylori infection 0.00000186 44 cGMP-PKG signaling pathway 0.00000246 45 Pathways in cancer 0.00000364 46 Starch and sucrose metabolism 0.00000408 47 Vibrio cholerae infection 0.00000599 48 Protein digestion and absorption 0.00000748 49 Morphine addiction 0.0000105 50 Regulation of lipolysis in adipocytes 0.0000139 51 Pancreatic secretion 0.0000218 52 Neurotrophin signaling pathway 0.0000243 53 Renin secretion 0.0000285 54 GnRH signaling pathway 0.0000324 55 AMPK signaling pathway 0.0000334 56 Insulin resistance 0.0000457 57 Viral myocarditis 0.0000544 58 Long-term depression 0.0000944 59 Dopaminergic synapse 0.0000986 60 Chagas disease (American trypanosomiasis) 0.0000986 61 Endocrine and other factor-regulated calcium reabsorption 0.000119 62 ErbB signaling pathway 0.000126 63 Central carbon metabolism in cancer 0.000127 64 Melanogenesis 0.000154 65 Adipocytokine signaling pathway 0.000178 66 Glucagon signaling pathway 0.000358 67 Fc epsilon RI signaling pathway 0.000363 68 Salivary secretion 0.000365 69 Progesterone-mediated oocyte maturation 0.000435 70 B cell receptor signaling pathway 0.000576 71 Choline metabolism in cancer 0.000689 72 Glycolysis / Gluconeogenesis 0.000734 73 Jak-STAT signaling pathway 0.000753 74 Lysosome 0.000807 75 Prolactin signaling pathway 0.000846 76 HIF-1 signaling pathway 0.000929 77 Hematopoietic cell lineage 0.00151 78 Aldosterone-regulated sodium reabsorption 0.00154 79 Complement and coagulation cascades 0.00184 80 Insulin secretion 0.00266 81 PPAR signaling pathway 0.00384 82 SNARE interactions in vesicular transport 0.00418 83 Pentose and glucuronate interconversions 0.00645 84 Fructose and mannose metabolism 0.00757 85 Endometrial cancer 0.00982 86 FoxO signaling pathway 0.012 87 Phosphatidylinositol signaling system 0.016 88 Tuberculosis 0.0181 89 Neuroactive ligand-receptor interaction 0.0232 90 mTOR signaling pathway 0.0237 91 Cocaine addiction 0.0286 92 Type II diabetes mellitus 0.0301 93 Glioma 0.0308 94 Hippo signaling pathway 0.0467