{"text_format":"3","workbook":"xls","n_sheets":2,"sheets":["Cluster properties and survival","Pathway analysis"],"not_rendered":{"external_links":1,"defined_names":3},"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Cluster properties and survival","index":0,"n_rows":41,"n_cols":22,"rows_kept":41,"merged":[[2,1,2,3],[2,4,2,6],[2,7,2,9],[2,10,2,12],[2,13,2,15],[2,16,2,18],[2,19,2,21]],"flags":["formulas_cached_only"]}
["Supplementary Data 1. Survival analysis and clustering quality for subtypes discovered by CIMLR using multi-omic data compared to subtypes discovered using single omic data in 32 cancer types from TCGA."]
[]
[null,"NUMBER OF CLUSTERS",null,null,"OS",null,null,"DSS",null,null,"DFI",null,null,"PFI",null,null,"SILHOUETTE",null,null,"STABILITY*"]
["CANCER","Multi-omic","Methylation","Expression","Multi-omic","Methylation","Expression","Multi-omic","Methylation","Expression","Multi-omic","Methylation","Expression","Multi-omic","Methylation","Expression","Multi-omic","Methylation","Expression","Multi-omic","Methylation","Expression"]
["acute_myeloid_leukemia",13,12,7,{"v":0.0011210246765521,"d":"1.12E-03"},{"v":0.02154301,"d":"2.15E-02"},{"v":0.011123226159289,"d":"1.11E-02"},"NA","NA","NA","NA","NA","NA","NA","NA","NA",{"v":0.8707115,"d":"8.71E-01"},{"v":0.7566059,"d":"7.57E-01"},{"v":0.9241181,"d":"9.24E-01"},{"v":0.9148961,"d":"9.15E-01"},{"v":0.8996319,"d":"9.00E-01"},{"v":0.9025168,"d":"9.03E-01"}]
["adrenocortical_carcinoma",6,5,3,{"v":6.7747207680675e-06,"d":"6.77E-06"},{"v":7.856209193940739e-06,"d":"7.86E-06"},{"v":0.00027687298089524405,"d":"2.77E-04"},{"v":8.73147050586334e-06,"d":"8.73E-06"},{"v":2.7389669740420903e-05,"d":"2.74E-05"},{"v":0.000223525751613846,"d":"2.24E-04"},{"v":0.000389929579197879,"d":"3.90E-04"},{"v":0.000491511761445127,"d":"4.92E-04"},{"v":0.0153960145075553,"d":"1.54E-02"},{"v":3.95345309484227e-10,"d":"3.95E-10"},{"v":3.50509563331e-08,"d":"3.51E-08"},{"v":6.70646353e-07,"d":"6.71E-07"},{"v":0.7910287,"d":"7.91E-01"},{"v":0.8022536,"d":"8.02E-01"},{"v":0.7981468,"d":"7.98E-01"},{"v":0.894359,"d":"8.94E-01"},{"v":0.8846417,"d":"8.85E-01"},{"v":0.8924816,"d":"8.92E-01"}]
["breast_cancer",13,13,10,{"v":0.0025323117101287,"d":"2.53E-03"},{"v":0.0977212098177609,"d":"9.77E-02"},{"v":0.0515612816964324,"d":"5.16E-02"},{"v":0.00212044188405276,"d":"2.12E-03"},{"v":0.391327417471626,"d":"3.91E-01"},{"v":0.0397813507710755,"d":"3.98E-02"},{"v":0.005450358837953841,"d":"5.45E-03"},{"v":0.41088146352493504,"d":"4.11E-01"},{"v":0.32354167007247403,"d":"3.24E-01"},{"v":0.0357187975068902,"d":"3.57E-02"},{"v":0.433539799659676,"d":"4.34E-01"},{"v":0.322521494143239,"d":"3.23E-01"},{"v":0.7608466,"d":"7.61E-01"},{"v":0.6970244,"d":"6.97E-01"},{"v":0.7024617,"d":"7.02E-01"},{"v":0.9175416,"d":"9.18E-01"},{"v":0.9029796,"d":"9.03E-01"},{"v":0.8935916,"d":"8.94E-01"}]
["cervical_cancer",11,3,7,{"v":0.48593317329018804,"d":"4.86E-01"},{"v":0.7491421729883251,"d":"7.49E-01"},{"v":0.47953484694959503,"d":"4.80E-01"},{"v":0.8591744890980281,"d":"8.59E-01"},{"v":0.882624271749567,"d":"8.83E-01"},{"v":0.6246003991104371,"d":"6.25E-01"},{"v":0.380328539736624,"d":"3.80E-01"},{"v":0.40503872854127504,"d":"4.05E-01"},{"v":0.058885032904580796,"d":"5.89E-02"},{"v":0.75663183156218,"d":"7.57E-01"},{"v":0.403899493705411,"d":"4.04E-01"},{"v":0.199777365710644,"d":"2.00E-01"},{"v":0.9173056,"d":"9.17E-01"},{"v":0.7576163,"d":"7.58E-01"},{"v":0.8601384,"d":"8.60E-01"},{"v":0.9179398,"d":"9.18E-01"},{"v":0.7706604,"d":"7.71E-01"},{"v":0.8996155,"d":"9.00E-01"}]
["cholangiocarcinoma",3,2,3,{"v":0.242872668567184,"d":"2.43E-01"},{"v":0.687827351232275,"d":"6.88E-01"},{"v":0.81913820189607,"d":"8.19E-01"},{"v":0.21563227621086,"d":"2.16E-01"},{"v":0.930604442888993,"d":"9.31E-01"},{"v":0.48278269650269406,"d":"4.83E-01"},{"v":0.56254794714464,"d":"5.63E-01"},{"v":0.100516602252256,"d":"1.01E-01"},{"v":0.034459798499684696,"d":"3.45E-02"},{"v":0.0918862984396803,"d":"9.19E-02"},{"v":0.234785893081434,"d":"2.35E-01"},{"v":0.201115914146067,"d":"2.01E-01"},{"v":0.9388109,"d":"9.39E-01"},{"v":0.6469787,"d":"6.47E-01"},{"v":0.8770271,"d":"8.77E-01"},{"v":0.8522199,"d":"8.52E-01"},{"v":1,"d":"1.00E+00"},{"v":0.9297514,"d":"9.30E-01"}]
["chromophobe_renal_cell_carcinoma",7,7,3,{"v":5.03050758736933e-06,"d":"5.03E-06"},{"v":0.20343813999908203,"d":"2.03E-01"},{"v":0.0586169861159895,"d":"5.86E-02"},{"v":3.38510809139998e-09,"d":"3.39E-09"},{"v":0.352415051504799,"d":"3.52E-01"},{"v":0.0402465085285565,"d":"4.02E-02"},{"v":0.7013090315753311,"d":"7.01E-01"},{"v":0.22225906519368,"d":"2.22E-01"},{"v":0.745974401856617,"d":"7.46E-01"},{"v":0.000246579708722817,"d":"2.47E-04"},{"v":0.14936987339985,"d":"1.49E-01"},{"v":0.277178364403698,"d":"2.77E-01"},{"v":0.6718416,"d":"6.72E-01"},{"v":0.6138981,"d":"6.14E-01"},{"v":0.9119597,"d":"9.12E-01"},{"v":0.8821037,"d":"8.82E-01"},{"v":0.8658936,"d":"8.66E-01"},{"v":0.9093017,"d":"9.09E-01"}]
["clear_cell_renal_cell_carcinoma",10,3,13,{"v":1.9199153856105797e-06,"d":"1.92E-06"},{"v":4.3714547618603704e-10,"d":"4.37E-10"},{"v":1.16342804330677e-07,"d":"1.16E-07"},{"v":1.02981031726015e-07,"d":"1.03E-07"},{"v":3.8173248899497e-06,"d":"3.82E-06"},{"v":3.1876133006600303e-09,"d":"3.19E-09"},{"v":0.49085777531469205,"d":"4.91E-01"},{"v":0.549965526397401,"d":"5.50E-01"},{"v":0.49397815609079704,"d":"4.94E-01"},{"v":4.98226075634596e-06,"d":"4.98E-06"},{"v":0.000383771038055847,"d":"3.84E-04"},{"v":7.875817029e-07,"d":"7.88E-07"},{"v":0.8676953,"d":"8.68E-01"},{"v":0.840455,"d":"8.40E-01"},{"v":0.8337897,"d":"8.34E-01"},{"v":0.9193371,"d":"9.19E-01"},{"v":0.9129876,"d":"9.13E-01"},{"v":0.9123486,"d":"9.12E-01"}]
["colon_rectal_cancer",11,5,6,{"v":0.46570420103459803,"d":"4.66E-01"},{"v":0.672376666130284,"d":"6.72E-01"},{"v":0.0635715244372963,"d":"6.36E-02"},{"v":0.243173529470663,"d":"2.43E-01"},{"v":0.128528627057256,"d":"1.29E-01"},{"v":0.324354124459709,"d":"3.24E-01"},{"v":0.129587752265849,"d":"1.30E-01"},{"v":0.803696766162692,"d":"8.04E-01"},{"v":0.149993435278093,"d":"1.50E-01"},{"v":0.33875812258307,"d":"3.39E-01"},{"v":0.204993438718693,"d":"2.05E-01"},{"v":0.0624070684499426,"d":"6.24E-02"},{"v":0.9191811,"d":"9.19E-01"},{"v":0.8770054,"d":"8.77E-01"},{"v":0.8590632,"d":"8.59E-01"},{"v":0.9167074,"d":"9.17E-01"},{"v":0.8964795,"d":"8.96E-01"},{"v":0.8856705,"d":"8.86E-01"}]
["cutaneous_melanoma",4,3,11,{"v":4.74e-08,"d":"4.74E-08"},{"v":0.05797326,"d":"5.80E-02"},{"v":0.04098422,"d":"4.10E-02"},{"v":7.05e-08,"d":"7.05E-08"},{"v":0.06792277,"d":"6.79E-02"},{"v":0.04849048,"d":"4.85E-02"},"NA","NA","NA",{"v":0.008629306,"d":"8.63E-03"},{"v":0.4099371,"d":"4.10E-01"},{"v":0.3831637,"d":"3.83E-01"},{"v":0.888598,"d":"8.89E-01"},{"v":0.8563285,"d":"8.56E-01"},{"v":0.8654277,"d":"8.65E-01"},{"v":0.8990517,"d":"8.99E-01"},{"v":0.8874439,"d":"8.87E-01"},{"v":0.9139201,"d":"9.14E-01"}]
["endometrial_carcinoma",11,6,10,{"v":0.8761791129001971,"d":"8.76E-01"},{"v":0.553467591757424,"d":"5.53E-01"},{"v":0.10006069160222701,"d":"1.00E-01"},{"v":0.601016110902402,"d":"6.01E-01"},{"v":0.41100151340421104,"d":"4.11E-01"},{"v":0.21485604756188803,"d":"2.15E-01"},{"v":0.207130779691335,"d":"2.07E-01"},{"v":0.158837253115467,"d":"1.59E-01"},{"v":0.286010007241493,"d":"2.86E-01"},{"v":0.474628131069438,"d":"4.75E-01"},{"v":0.610819130340317,"d":"6.11E-01"},{"v":0.627792271439587,"d":"6.28E-01"},{"v":0.8501434,"d":"8.50E-01"},{"v":0.9534812,"d":"9.53E-01"},{"v":0.8935054,"d":"8.94E-01"},{"v":0.9054447,"d":"9.05E-01"},{"v":0.8809795,"d":"8.81E-01"},{"v":0.9097366,"d":"9.10E-01"}]
["gastric_adenocarcinoma",3,5,2,{"v":0.0993025194554094,"d":"9.93E-02"},{"v":0.009751049938049131,"d":"9.75E-03"},{"v":0.30915720236460204,"d":"3.09E-01"},{"v":0.21969908352453,"d":"2.20E-01"},{"v":0.026294464520735004,"d":"2.63E-02"},{"v":0.7337744269731431,"d":"7.34E-01"},{"v":0.39900842106670104,"d":"3.99E-01"},{"v":0.671503445431312,"d":"6.72E-01"},{"v":0.5927675795131381,"d":"5.93E-01"},{"v":0.0326696823995524,"d":"3.27E-02"},{"v":0.386625393768014,"d":"3.87E-01"},{"v":0.877087362928724,"d":"8.77E-01"},{"v":0.7432232,"d":"7.43E-01"},{"v":0.7974209,"d":"7.97E-01"},{"v":0.7398308,"d":"7.40E-01"},{"v":0.8580299,"d":"8.58E-01"},{"v":0.8613412,"d":"8.61E-01"},{"v":1,"d":"1.00E+00"}]
["glioblastoma",8,2,5,{"v":0.0107298950423412,"d":"1.07E-02"},{"v":0.669502980588338,"d":"6.70E-01"},{"v":0.27327349562094905,"d":"2.73E-01"},{"v":0.005590839058169311,"d":"5.59E-03"},{"v":0.554437508793306,"d":"5.54E-01"},{"v":0.13847918088069602,"d":"1.38E-01"},"NA","NA","NA",{"v":0.146146629828668,"d":"1.46E-01"},{"v":0.691295233541039,"d":"6.91E-01"},{"v":0.0072510681014812,"d":"7.25E-03"},{"v":0.9269429,"d":"9.27E-01"},{"v":0.8542495,"d":"8.54E-01"},{"v":0.9348102,"d":"9.35E-01"},{"v":0.904726,"d":"9.05E-01"},{"v":1,"d":"1.00E+00"},{"v":0.893233,"d":"8.93E-01"}]
["head_neck_squamous_cell_carcinoma",8,5,3,{"v":0.00855535813649861,"d":"8.56E-03"},{"v":0.0067922769618512305,"d":"6.79E-03"},{"v":0.10955633516131,"d":"1.10E-01"},{"v":0.00620395590847964,"d":"6.20E-03"},{"v":0.005799492314923981,"d":"5.80E-03"},{"v":0.0197786568419771,"d":"1.98E-02"},{"v":0.26917350531314205,"d":"2.69E-01"},{"v":0.270085395439194,"d":"2.70E-01"},{"v":0.0398976095353772,"d":"3.99E-02"},{"v":0.00842431424158197,"d":"8.42E-03"},{"v":0.0152322118099777,"d":"1.52E-02"},{"v":0.0345376800316975,"d":"3.45E-02"},{"v":0.8580291,"d":"8.58E-01"},{"v":0.7132444,"d":"7.13E-01"},{"v":0.7568234,"d":"7.57E-01"},{"v":0.9036839,"d":"9.04E-01"},{"v":0.8132191,"d":"8.13E-01"},{"v":0.844656,"d":"8.45E-01"}]
["liver_hepatocellular_carcinoma",8,5,12,{"v":0.000270237934214335,"d":"2.70E-04"},{"v":0.370519977467312,"d":"3.71E-01"},{"v":0.00021668117731884503,"d":"2.17E-04"},{"v":0.004698920808340131,"d":"4.70E-03"},{"v":0.6752863354531571,"d":"6.75E-01"},{"v":6.75679200276533e-05,"d":"6.76E-05"},{"v":0.0767532393687701,"d":"7.68E-02"},{"v":0.15562258502505702,"d":"1.56E-01"},{"v":0.10369002915656501,"d":"1.04E-01"},{"v":0.0189339709323459,"d":"1.89E-02"},{"v":0.273012376177601,"d":"2.73E-01"},{"v":0.0685407634114193,"d":"6.85E-02"},{"v":0.8654255,"d":"8.65E-01"},{"v":0.7519408,"d":"7.52E-01"},{"v":0.8030825,"d":"8.03E-01"},{"v":0.8974323,"d":"8.97E-01"},{"v":0.9007487,"d":"9.01E-01"},{"v":0.9145002,"d":"9.15E-01"}]
["lower_grade_glioma",3,4,12,{"v":1.79270397223357e-24,"d":"1.79E-24"},{"v":1.38289221650608e-10,"d":"1.38E-10"},{"v":4.1405323136486395e-19,"d":"4.14E-19"},{"v":1.21708273518054e-24,"d":"1.22E-24"},{"v":1.19986591998178e-09,"d":"1.20E-09"},{"v":2.333735684144e-18,"d":"2.33E-18"},{"v":0.208558222833283,"d":"2.09E-01"},{"v":0.00226551738277243,"d":"2.27E-03"},{"v":0.27661353897733504,"d":"2.77E-01"},{"v":6.12042e-23,"d":"6.12E-23"},{"v":1.106444011378e-07,"d":"1.11E-07"},{"v":1.137617e-10,"d":"1.14E-10"},{"v":0.7743834,"d":"7.74E-01"},{"v":0.771589,"d":"7.72E-01"},{"v":0.6558003,"d":"6.56E-01"},{"v":0.8850146,"d":"8.85E-01"},{"v":0.862835,"d":"8.63E-01"},{"v":0.8903514,"d":"8.90E-01"}]
["lung_adenocarcinoma",8,15,14,{"v":0.00213788398868325,"d":"2.14E-03"},{"v":0.0239671071799102,"d":"2.40E-02"},{"v":0.00150330780570996,"d":"1.50E-03"},{"v":0.00690497091480066,"d":"6.90E-03"},{"v":0.006779987209797111,"d":"6.78E-03"},{"v":0.00282456078713934,"d":"2.82E-03"},{"v":0.46811031648952506,"d":"4.68E-01"},{"v":0.033859000328319004,"d":"3.39E-02"},{"v":0.9566188646915631,"d":"9.57E-01"},{"v":0.0395147474867498,"d":"3.95E-02"},{"v":0.00502580014252178,"d":"5.03E-03"},{"v":0.0215121590419727,"d":"2.15E-02"},{"v":0.9142587,"d":"9.14E-01"},{"v":0.8854417,"d":"8.85E-01"},{"v":0.8147588,"d":"8.15E-01"},{"v":0.9060893,"d":"9.06E-01"},{"v":0.9227684,"d":"9.23E-01"},{"v":0.9192205,"d":"9.19E-01"}]
["lymphoid_neoplasm_diffuse_large_b_cell_lymphoma",3,3,2,{"v":0.602380773590231,"d":"6.02E-01"},{"v":0.173269524830469,"d":"1.73E-01"},{"v":0.413270135568901,"d":"4.13E-01"},{"v":0.39328764451922804,"d":"3.93E-01"},{"v":0.377265337012742,"d":"3.77E-01"},{"v":0.9473672626889841,"d":"9.47E-01"},{"v":0.39799133971161404,"d":"3.98E-01"},{"v":0.334413456052489,"d":"3.34E-01"},{"v":0.5792287447730381,"d":"5.79E-01"},{"v":0.979779831603235,"d":"9.80E-01"},{"v":0.0527214930457406,"d":"5.27E-02"},{"v":0.504681799667148,"d":"5.05E-01"},{"v":0.8307505,"d":"8.31E-01"},{"v":0.7962912,"d":"7.96E-01"},{"v":0.8796615,"d":"8.80E-01"},{"v":0.9036101,"d":"9.04E-01"},{"v":0.9164987,"d":"9.16E-01"},{"v":1,"d":"1.00E+00"}]
["oesophageal_carcinoma",3,2,2,{"v":0.37824327564346605,"d":"3.78E-01"},{"v":0.766936692707305,"d":"7.67E-01"},{"v":0.35787956229411205,"d":"3.58E-01"},{"v":0.154604541160962,"d":"1.55E-01"},{"v":0.760500839606507,"d":"7.61E-01"},{"v":0.841969468693692,"d":"8.42E-01"},{"v":0.0956974824868684,"d":"9.57E-02"},{"v":0.128378840601431,"d":"1.28E-01"},{"v":0.162934984800559,"d":"1.63E-01"},{"v":0.145400870631058,"d":"1.45E-01"},{"v":0.648548138208338,"d":"6.49E-01"},{"v":0.774645896283371,"d":"7.75E-01"},{"v":0.8649483,"d":"8.65E-01"},{"v":0.8385058,"d":"8.39E-01"},{"v":0.8420648,"d":"8.42E-01"},{"v":0.9003775,"d":"9.00E-01"},{"v":1,"d":"1.00E+00"},{"v":1,"d":"1.00E+00"}]
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["pancreatic_adenocarcinoma",12,13,11,{"v":0.0303075845463727,"d":"3.03E-02"},{"v":0.6987729914142751,"d":"6.99E-01"},{"v":0.268469373903063,"d":"2.68E-01"},{"v":0.0003640033984323,"d":"3.64E-04"},{"v":0.691895134444733,"d":"6.92E-01"},{"v":0.265093621481275,"d":"2.65E-01"},{"v":0.0998144000425038,"d":"9.98E-02"},{"v":0.935884328013674,"d":"9.36E-01"},{"v":0.38613739934352603,"d":"3.86E-01"},{"v":0.0371601097327506,"d":"3.72E-02"},{"v":0.63211055368699,"d":"6.32E-01"},{"v":0.0889126167209012,"d":"8.89E-02"},{"v":0.8960287,"d":"8.96E-01"},{"v":0.88955,"d":"8.90E-01"},{"v":0.9183016,"d":"9.18E-01"},{"v":0.9177295,"d":"9.18E-01"},{"v":0.9146431,"d":"9.15E-01"},{"v":0.9198081,"d":"9.20E-01"}]
["papillary_renal_cell_carcinoma",8,8,10,{"v":0.0236328324094717,"d":"2.36E-02"},{"v":4.657406392956951e-13,"d":"4.66E-13"},{"v":4.74216724649785e-10,"d":"4.74E-10"},{"v":8.488747916679219e-06,"d":"8.49E-06"},{"v":2.9797800456532e-21,"d":"2.98E-21"},{"v":1.7694581417005201e-15,"d":"1.77E-15"},{"v":0.025350022287779498,"d":"2.54E-02"},{"v":5.2981190080210205e-05,"d":"5.30E-05"},{"v":0.000254247498623958,"d":"2.54E-04"},{"v":1.20865039576292e-05,"d":"1.21E-05"},{"v":5.883947e-13,"d":"5.88E-13"},{"v":1.009945e-10,"d":"1.01E-10"},{"v":0.8533963,"d":"8.53E-01"},{"v":0.8766118,"d":"8.77E-01"},{"v":0.880501,"d":"8.81E-01"},{"v":0.9026474,"d":"9.03E-01"},{"v":0.8986599,"d":"8.99E-01"},{"v":0.91768,"d":"9.18E-01"}]
["papillary_thyroid_carcinoma",10,3,14,{"v":0.237260656478805,"d":"2.37E-01"},{"v":0.65364564310039,"d":"6.54E-01"},{"v":0.0404282415500203,"d":"4.04E-02"},{"v":0.046937674884683096,"d":"4.69E-02"},{"v":0.911499985794447,"d":"9.11E-01"},{"v":0.650456132700551,"d":"6.50E-01"},{"v":0.331046471165771,"d":"3.31E-01"},{"v":0.9920668651298461,"d":"9.92E-01"},{"v":0.820327312030606,"d":"8.20E-01"},{"v":0.270502415704437,"d":"2.71E-01"},{"v":0.512339619805575,"d":"5.12E-01"},{"v":0.413498726748579,"d":"4.13E-01"},{"v":0.2624868,"d":"2.62E-01"},{"v":0.7504641,"d":"7.50E-01"},{"v":0.834286,"d":"8.34E-01"},{"v":0.7169099,"d":"7.17E-01"},{"v":1,"d":"1.00E+00"},{"v":0.9183679,"d":"9.18E-01"}]
["pheochromocytoma_paraganglioma",5,9,2,{"v":0.0207229071040273,"d":"2.07E-02"},{"v":0.518782765026885,"d":"5.19E-01"},{"v":0.876441674754128,"d":"8.76E-01"},{"v":0.0261528142624821,"d":"2.62E-02"},{"v":0.6390315140716131,"d":"6.39E-01"},{"v":0.6319574845358821,"d":"6.32E-01"},{"v":0.0472273175741435,"d":"4.72E-02"},{"v":0.781480490541637,"d":"7.81E-01"},{"v":0.37023053645839205,"d":"3.70E-01"},{"v":0.0141437980854959,"d":"1.41E-02"},{"v":0.0764868395825061,"d":"7.65E-02"},{"v":0.014815761301545,"d":"1.48E-02"},{"v":0.8423451,"d":"8.42E-01"},{"v":0.9141972,"d":"9.14E-01"},{"v":0.7420828,"d":"7.42E-01"},{"v":0.9081523,"d":"9.08E-01"},{"v":0.9110063,"d":"9.11E-01"},{"v":1,"d":"1.00E+00"}]
["pleural_mesothelioma",7,5,5,{"v":0.028866199999999998,"d":"2.89E-02"},{"v":0.214666159811313,"d":"2.15E-01"},{"v":6.48674163665835e-05,"d":"6.49E-05"},{"v":0.02621817,"d":"2.62E-02"},{"v":0.5185991199859851,"d":"5.19E-01"},{"v":0.000536467261919216,"d":"5.36E-04"},{"v":0.05181831,"d":"5.18E-02"},{"v":0.876434352377472,"d":"8.76E-01"},{"v":0.0260743739236211,"d":"2.61E-02"},{"v":7.06593122033583e-06,"d":"7.07E-06"},{"v":0.628808999448737,"d":"6.29E-01"},{"v":0.0017382295551636,"d":"1.74E-03"},{"v":-0.197015,"d":"-1.97E-01"},{"v":0.6375322,"d":"6.38E-01"},{"v":0.8972999,"d":"8.97E-01"},{"v":0.5293855,"d":"5.29E-01"},{"v":0.8292073,"d":"8.29E-01"},{"v":0.9073419,"d":"9.07E-01"}]
["prostate_cancer",3,5,6,{"v":0.5564188022075941,"d":"5.56E-01"},{"v":0.46692608397810104,"d":"4.67E-01"},{"v":0.731828048083611,"d":"7.32E-01"},{"v":0.17859820678842903,"d":"1.79E-01"},{"v":0.8739363215712471,"d":"8.74E-01"},{"v":0.366285327289722,"d":"3.66E-01"},{"v":0.00203527346684065,"d":"2.04E-03"},{"v":0.013727299819426799,"d":"1.37E-02"},{"v":0.11157767852662501,"d":"1.12E-01"},{"v":7.38367998524849e-05,"d":"7.38E-05"},{"v":0.00373295716412791,"d":"3.73E-03"},{"v":0.0261466158142437,"d":"2.61E-02"},{"v":0.7145706,"d":"7.15E-01"},{"v":0.7325046,"d":"7.33E-01"},{"v":0.7728487,"d":"7.73E-01"},{"v":1,"d":"1.00E+00"},{"v":0.8536577,"d":"8.54E-01"},{"v":0.8967582,"d":"8.97E-01"}]
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["squamous_cell_lung_cancer",7,8,8,{"v":0.623434003023837,"d":"6.23E-01"},{"v":0.7115207480941891,"d":"7.12E-01"},{"v":0.31408137432529804,"d":"3.14E-01"},{"v":0.9143053382788421,"d":"9.14E-01"},{"v":0.912330071855007,"d":"9.12E-01"},{"v":0.85597135885446,"d":"8.56E-01"},{"v":0.0110406509524344,"d":"1.10E-02"},{"v":0.19775842606360403,"d":"1.98E-01"},{"v":0.393638413520679,"d":"3.94E-01"},{"v":0.799599944513965,"d":"8.00E-01"},{"v":0.856911671760201,"d":"8.57E-01"},{"v":0.290137089515262,"d":"2.90E-01"},{"v":0.9282437,"d":"9.28E-01"},{"v":0.9102345,"d":"9.10E-01"},{"v":0.8141293,"d":"8.14E-01"},{"v":0.9021494,"d":"9.02E-01"},{"v":0.8959721,"d":"8.96E-01"},{"v":0.8831879,"d":"8.83E-01"}]
["testicular_germ_cell_cancer",7,4,6,{"v":0.0450644640337029,"d":"4.51E-02"},{"v":0.30490822869378703,"d":"3.05E-01"},{"v":0.39588062159205706,"d":"3.96E-01"},{"v":0.310387754398256,"d":"3.10E-01"},{"v":0.544237166406594,"d":"5.44E-01"},{"v":0.5390982169478661,"d":"5.39E-01"},{"v":0.156887007973005,"d":"1.57E-01"},{"v":0.15070177033547302,"d":"1.51E-01"},{"v":0.639886707958462,"d":"6.40E-01"},{"v":0.189516250169985,"d":"1.90E-01"},{"v":0.369451521073955,"d":"3.69E-01"},{"v":0.567440296382855,"d":"5.67E-01"},{"v":0.9169269,"d":"9.17E-01"},{"v":0.8798638,"d":"8.80E-01"},{"v":0.930674,"d":"9.31E-01"},{"v":0.9030441,"d":"9.03E-01"},{"v":0.916203,"d":"9.16E-01"},{"v":0.9123105,"d":"9.12E-01"}]
["thymoma",7,8,10,{"v":0.0356638595268238,"d":"3.57E-02"},{"v":0.11460086523192801,"d":"1.15E-01"},{"v":0.0854201425228141,"d":"8.54E-02"},{"v":0.14267011534099902,"d":"1.43E-01"},{"v":0.19567703669719602,"d":"1.96E-01"},{"v":0.44338226391131,"d":"4.43E-01"},"NA","NA","NA",{"v":0.443327219305887,"d":"4.43E-01"},{"v":0.00870020410017427,"d":"8.70E-03"},{"v":0.0964807511938738,"d":"9.65E-02"},{"v":0.8951632,"d":"8.95E-01"},{"v":0.9376957,"d":"9.38E-01"},{"v":0.9566979,"d":"9.57E-01"},{"v":0.9088354,"d":"9.09E-01"},{"v":0.916923,"d":"9.17E-01"},{"v":0.9165247,"d":"9.17E-01"}]
["urothelial_bladder_carcinoma",5,11,5,{"v":0.0654956980709403,"d":"6.55E-02"},{"v":0.004370433751720961,"d":"4.37E-03"},{"v":0.40586821695456504,"d":"4.06E-01"},{"v":0.12241731844316701,"d":"1.22E-01"},{"v":0.0602512391865301,"d":"6.03E-02"},{"v":0.49060796751880603,"d":"4.91E-01"},{"v":0.197007541732679,"d":"1.97E-01"},{"v":0.000599656158430177,"d":"6.00E-04"},{"v":0.9262636685639031,"d":"9.26E-01"},{"v":0.564297553487943,"d":"5.64E-01"},{"v":0.55613071308517,"d":"5.56E-01"},{"v":0.444778858498955,"d":"4.45E-01"},{"v":0.9341348,"d":"9.34E-01"},{"v":0.9447964,"d":"9.45E-01"},{"v":0.914445,"d":"9.14E-01"},{"v":0.8734922,"d":"8.73E-01"},{"v":0.907423,"d":"9.07E-01"},{"v":0.9007712,"d":"9.01E-01"}]
["uterine_carcinosarcoma",2,5,3,{"v":0.374951440790773,"d":"3.75E-01"},{"v":0.7520840312886581,"d":"7.52E-01"},{"v":0.542907270880658,"d":"5.43E-01"},{"v":0.281883412047086,"d":"2.82E-01"},{"v":0.7809732293276891,"d":"7.81E-01"},{"v":0.820644337188362,"d":"8.21E-01"},{"v":0.436082084117055,"d":"4.36E-01"},{"v":0.24618239920078502,"d":"2.46E-01"},{"v":0.449779349175889,"d":"4.50E-01"},{"v":0.319265643636715,"d":"3.19E-01"},{"v":0.342217156327836,"d":"3.42E-01"},{"v":0.589648905182514,"d":"5.90E-01"},{"v":0.8910962,"d":"8.91E-01"},{"v":0.7850941,"d":"7.85E-01"},{"v":0.6031981,"d":"6.03E-01"},{"v":1,"d":"1.00E+00"},{"v":0.8922999,"d":"8.92E-01"},{"v":0.7986172,"d":"7.99E-01"}]
["uveal_melanoma",3,6,4,{"v":0.0049438092050287505,"d":"4.94E-03"},{"v":2.03511376300125e-06,"d":"2.04E-06"},{"v":1.1970208050208401e-05,"d":"1.20E-05"},{"v":0.00265251054275585,"d":"2.65E-03"},{"v":9.875551210498979e-07,"d":"9.88E-07"},{"v":2.8281914806062302e-05,"d":"2.83E-05"},"NA","NA","NA",{"v":0.00068074742804534,"d":"6.81E-04"},{"v":4.3602199407e-09,"d":"4.36E-09"},{"v":7.01366214478e-05,"d":"7.01E-05"},{"v":0.9409349,"d":"9.41E-01"},{"v":0.703544,"d":"7.04E-01"},{"v":0.7697264,"d":"7.70E-01"},{"v":0.8898461,"d":"8.90E-01"},{"v":0.9342859,"d":"9.34E-01"},{"v":0.9034326,"d":"9.03E-01"}]
[]
["TOTAL SIGNIFICANT",{"$nulls":3},19,12,12,17,10,13,6,7,6,16,10,12]
["TOTAL SURVIVAL SIGNIFICANT (any metric)",23,14,20]
[]
["*Stability is measured as the normalized mutual information of the results over 100 new independent runs of k-means with respect to the original results."]

{"sheet":"Pathway analysis","index":1,"n_rows":37,"n_cols":37,"rows_kept":37,"flags":["formulas_cached_only"]}
["Supplementary Data 1. Survival analysis and clustering quality for subtypes discovered by CIMLR using multi-omic data compared to subtypes discovered using single omic data in 32 cancer types from TCGA."]
[]
["CANCER","MULTI-OMIC",{"$nulls":11},"METHYLATION",{"$nulls":11},"EXPRESSION"]
[null,"EGFR","Hypoxia","JAK-STAT","MAPK","NFkB","PI3K","TGFb","TNFa","Trail","VEGF","p53","Total significant","EGFR","Hypoxia","JAK-STAT","MAPK","NFkB","PI3K","TGFb","TNFa","Trail","VEGF","p53","Total significant","EGFR","Hypoxia","JAK-STAT","MAPK","NFkB","PI3K","TGFb","TNFa","Trail","VEGF","p53","Total significant"]
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[]
["Total significant",0,0,0,0,0,0,0,0,0,0,0,null,0,0,0,0,0,0,0,0,0,0,0,null,0,0,0,0,0,0,0,0,0,0,0]
[{"$nulls":36},26]
["Total significant (any pathway)",{"$nulls":11},26,{"$nulls":11},24,{"$nulls":11},{"v":0,"d":"0.00"}]
["Average number of significant pathways",{"$nulls":11},{"v":0,"d":"0.00"},{"$nulls":11},{"v":0,"d":"0.00"},{"$nulls":11},{"v":0,"d":"0.00"}]
["S.D.",{"$nulls":11},{"v":0,"d":"0.00"},{"$nulls":11},{"v":0,"d":"0.00"}]