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{"sheet":"Fig. 1f","index":3,"n_rows":1023,"n_cols":10,"rows_kept":1023,"merged":[[1,1,1,9],[11,1,11,9],[21,1,21,2]]}
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[null,"ATC concentration (ng/mL)",200,{"$nulls":4},100,{"$nulls":4},50,{"$nulls":4},20,{"$nulls":4},10,{"$nulls":4},0]
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[null,"ATC concentration (ng/mL)",200,{"$nulls":4},100,{"$nulls":4},50,{"$nulls":4},20,{"$nulls":4},10,{"$nulls":4},0]
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[null,"Fluorescence intensity ",{"$nulls":6},"Cell growth"]
[null,"Time (h)","rrnB P1-(teF)YFP",{"$nulls":5},"Time (h)","rrnB P1-(teF)YFP"]
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[null,2,23.70328,2.22914,-3.95962,-5.12611,-5.82581,null,2,0.1537,0.1882,0.1538,0.2048,0.1563]
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[null,4,48.90572,14.77384,16.36199,0.25678,2.78164,null,4,0.7656,0.8349,0.7782,0.8785,0.7929]
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[null,6,77.69561,83.68931,50.43648,12.40572,8.21219,null,6,1.1875,1.2074,1.207,1.2275,1.207]
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[null,7.5,197.84399,225.22223,147.36805,39.15602,20.80463,null,7.5,1.2534,1.2637,1.2757,1.2747,1.2691]
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[null,10,244.15633,218.90359,122.26112,2.66132,0.28196,null,10,1.2699,1.2768,1.2965,1.2904,1.2902]
[null,10.5,240.72383,211.30775,110.85376,0.31386,0.47001,null,10.5,1.2695,1.2767,1.2965,1.2904,1.2907]
[null,11,245.07518,204.75416,100.4533,0.35001,0.04703,null,11,1.2664,1.2729,1.2935,1.2868,1.2874]
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[null,13,234.44139,168.76661,42.95467,0.03674,0.77044]
[null,15,233.81084,146.56512,15.31456,0.16588,0.02156]
[null,17,234.01707,114.35151,1.01529,0.18861,0.56104]
[null,19,229.25623,95.31564,0.13548,0.80059,0.15852]
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[null,23,224.68079,48.43545,1.60121,0.03971,0.06095]

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[null,null,"Ptet-tev","Pfic-tev","PbolA-tev","Ps4-tev","Ps60-tev"]
[null,"rrnB P1-(teF)YFP",0.2,9,8.5,7.5,7]
[null,"rpsT P2-(teF)YFP",1,8,8,8,7]
[null,"rpsJ-(teF)YFP",4,10,9.5,8.5,8]
[null,"Ptrc-(teF)YFP",3,10,10,8.5,8.5]
[null,"Ptrc-(teF)YFP",24,24,24,24,24]

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[null,null,"GFP",null,"mCherry"]
[null,null,"ATC-","ATC＋","ATC-","ATC＋"]
[null,"Parallel 1",295.46975,2494.66,285.246,19.3385]
[null,"Parallel 2",58.44475,2881.017,284,20.3915]
[null,"Parallel 3",340.32075,2615.222,322.992,23.0725]
[null,"Parallel 4",175.98375,2717.147,298.154,25.9405]
[null,"Parallel 5",60.87125,2536.571,314.826,18.6735]
[null,"Parallel 6",377.02275,2339.636,298.606,18.2915]

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[]
[null,null,"GFP",null,"mCherry"]
[null,null,"ATC-","ATC＋","ATC-","ATC＋"]
[null,"Parallel 1",168.45218,1507.43147,292.77794,33.90698]
[null,"Parallel 2",264.71984,1820.50359,267.74114,30.5084]
[null,"Parallel 3",218.59858,1534.86624,309.74477,24.63246]
[null,"Parallel 4",289.16807,1754.9512,294.98077,37.12314]
[null,"Parallel 5",222.48167,1911.98345,265.47248,21.21852]
[null,"Parallel 6",367.46121,1734.25923,236.25394,34.01885]

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[null,"Time (h)","Control"]
[null,null,"Parallel 1","Parallel 2","Parallel 3","Parallel 4","Parallel 5","Parallel 6","Mean value"]
[null,0,1.15,69.161,59.915,198.95,101.568,89.884,86.77133]
[null,0.5,8.004,78.1195,97.6465,267.5475,221.5245,352.8315,170.94558]
[null,1,141.5995,246.813,125.787,264.7415,369.5295,252.2985,233.4615]
[null,1.5,219.1785,266.3285,271.699,303.439,379.477,355.9365,299.34308]
[null,2,235.2325,312.593,330.05,350.405,334.9145,439.898,333.84883]
[null,2.5,316.319,396.4625,405.72,446.3725,423.545,452.157,406.76267]
[null,3,403.0865,566.973,474.9385,484.334,601.473,664.5275,532.55542]
[null,3.5,432.929,594.7685,491.234,616.975,543.7775,637.261,552.82417]
[null,4,583.8245,634.8805,698.004,653.9475,640.895,702.4085,652.32667]
[null,4.5,673.44,741.566,686.1935,744.3145,701.8105,753.2615,716.76433]
[null,5,721.4985,779.2975,767.3145,786.968,824.849,810.8535,781.79683]
[null,5.5,733.539,761.162,838.994,817.7995,831.6685,860.614,807.29617]
[null,6,763.2435,781.5285,876.4035,827.425,861.7985,887.593,832.99867]
[null,6.5,869.5955,886.627,899.277,942.4365,956.9035,981.847,922.78108]
[null,7,982.92345,993.52974,963.63559,1008.60725,918.01126,988.91778,975.93751]
[null,7.5,1001.9991,887.82615,1070.93343,1034.50438,927.84686,1010.2027,988.88544]
[null,8,1043.1016,1041.94229,993.97569,1015.43896,1088.16473,1092.03473,1045.77633]
[null,8.5,1037.70396,1035.3411,1069.37122,1099.21953,1051.6336,1150.87052,1074.02332]
[null,9,1133.80149,1070.37483,1148.90132,1186.7966,1157.9188,1290.28024,1164.67888]
[null,9.5,1187.9369,1222.18031,1252.48319,1265.46234,1288.84443,1435.11126,1275.33641]
[null,10,1312.68176,1291.46044,1286.89564,1406.21457,1437.34022,1471.44269,1367.67255]
[null,10.5,1411.22895,1519.73279,1406.15261,1588.57049,1533.22593,1543.08733,1500.33302]
[null,11,1571.38816,1570.06336,1514.94288,1654.56615,1480.48241,1641.63275,1572.17928]
[null,11.5,1559.8127,1619.16357,1548.42382,1560.84103,1538.47295,1699.92373,1587.77297]
[null,12,1614.02614,1511.63723,1566.19336,1641.72287,1615.68296,1623.0675,1595.38834]

{"sheet":"Fig. 3d","index":11,"n_rows":28,"n_cols":9,"rows_kept":28,"merged":[[1,1,2,1],[1,2,1,8]]}
[]
[null,"Time (h)","pbO"]
[null,null,"Parallel 1","Parallel 2","Parallel 3","Parallel 4","Parallel 5","Parallel 6","Mean value"]
[null,0,166.02075,38.62705,58.56605,125.5903,143.5862,94.73565,104.521]
[null,0.5,331.6605,244.9195,269.93215,352.1202,185.45175,356.08895,290.02884]
[null,1,165.8747,160.1216,134.1501,163.4109,101.97465,128.7907,142.38711]
[null,1.5,531.42515,536.2067,595.7443,671.9189,555.371,545.338,572.66734]
[null,2,128.44145,301.75835,380.4158,90.8812,54.84495,175.4505,188.63204]
[null,2.5,255.0414,334.3021,326.009,223.0501,301.69485,294.68445,289.13032]
[null,3,567.7408,557.0601,599.44635,476.15475,553.4025,586.4479,556.70873]
[null,3.5,383.21615,409.03525,383.5908,342.5698,311.74055,419.7985,374.99184]
[null,4,216.9287,187.4393,208.1403,214.5665,216.42705,238.66475,213.69443]
[null,4.5,449.1355,459.25105,476.1103,475.97695,448.8942,504.6472,469.00253]
[null,5,94.7293,334.35925,291.20465,93.472,155.61945,225.2091,199.09896]
[null,5.5,261.874,253.71425,268.8463,206.3623,175.7553,333.3369,249.98151]
[null,6,489.73105,532.08555,524.3322,432.69535,574.8782,585.22235,523.15745]
[null,6.5,372.28145,530.06625,508.0127,431.76825,485.71785,563.37835,481.87081]
[null,7,351.76354,500.8509,480.01115,407.97065,458.94659,532.32601,455.31147]
[null,7.5,427.89557,449.27908,474.92956,442.24186,422.44035,495.17826,451.99411]
[null,8,420.2284,533.67985,555.38206,435.41963,510.91578,556.53055,502.02605]
[null,8.5,293.76408,478.55433,531.17807,316.35711,407.58225,525.11598,425.4253]
[null,9,453.65418,618.79229,604.76882,419.06378,579.42962,652.84848,554.75953]
[null,9.5,645.25385,834.8187,890.36394,581.56267,890.02017,923.98487,794.33403]
[null,10,696.39561,891.29898,914.01601,781.13456,809.53683,937.25524,838.27287]
[null,10.5,879.26156,1030.32206,1100.94766,873.9101,1025.72482,1061.58,995.29103]
[null,11,891.24027,1073.28088,1049.44279,955.31024,1020.97737,1132.84043,1020.51533]
[null,11.5,827.3475,1054.2895,906.0695,1057.9855,931.5265,1081.2475,976.411]
[null,12,801.3705,753.4405,840.5025,834.4875,894.9715,857.9455,830.453]

{"sheet":"Fig. 4","index":12,"n_rows":47,"n_cols":1,"rows_kept":47}
[]
[]
[]
[]
[]
[]
["Control system"]
{"$rows_empty":12}
["Control system"]
{"$rows_empty":14}
["pbO system"]
{"$rows_empty":11}
["pbO system"]

{"sheet":"Fig. 5b","index":13,"n_rows":17,"n_cols":14,"rows_kept":17,"merged":[[1,1,2,1],[1,2,1,6],[1,8,2,8],[1,9,1,13]]}
[]
[null,"Strains","Shikimate titer (g/L)",{"$nulls":5},"Strains","OD600"]
[null,null,"Parallel 1","Parallel 2","Parallel 3","Mean value","Error bar",null,null,"Parallel 1","Parallel 2","Parallel 3","Mean value","Error bar"]
[null,"+",0.03,0.05,0.06,{"$f":"AVERAGE(C4:E4)","v":0.04666666666666667},{"$f":"STDEVA(C4:E4)","v":0.015275252316519449},null,"+",7.65,7.11,7.38,{"$f":"AVERAGE(J4:L4)","v":7.38},{"$f":"STDEVA(J4:L4)","v":0.27}]
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[null,"DS1",0.02,0.035,0.072,0.042333333333333334,0.026764404221527757,null,"DS1",0.16,0.16,0.15,0.15666666666666665,0.005773502691896262]
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[null,"DS4",0.444,0.4566,0.442,0.44753333333333334,0.007915385861304131,null,"DS4",0.9,0.89,0.88,0.89,0.010000000000000009]
[null,"DS5",1.586,1.662,1.521,1.5896666666666668,0.07057147676882873,null,"DS5",6.01,5.94,5.86,5.9366666666666665,0.07505553499465109]
[null,"DS6",1.879,1.7677,1.981,1.8759,0.10668378508470724,null,"DS6",6.32,5.92,5.89,6.043333333333333,0.24006943440041148]
[null,"DS7",2.139,2.034,2.244,2.139,0.1050000000000002,null,"DS7",7.18,6.82,6.45,6.816666666666666,0.3650114153466069]
[null,"DS8",1.214,1.335,1.095,1.2146666666666668,0.12000138888085142,null,"DS8",6.8,6.7,5.99,6.496666666666667,0.44162578427140464]
[null,"DS9",1.292,1.345,1.238,1.2916666666666667,0.05350077881053071,null,"DS9",6.43,6.22,6,6.216666666666666,0.2150193789716017]
[null,"DS10",1.547,1.42,1.684,1.5503333333333333,0.13203156188326082,null,"DS10",6.42,6.35,6.27,6.346666666666667,0.07505553499465152]
[null,"DS11",0.627,0.738,0.525,0.63,0.10653168542738795,null,"DS11",6.41,6.32,6.2,6.31,0.10535653752852737]
[null,"DS12",0.445,0.621,0.285,0.4503333333333333,0.16806348007027982,null,"DS12",6.35,6.71,7.1,6.719999999999999,0.37509998667022104]

{"sheet":"Fig. 5c","index":14,"n_rows":7,"n_cols":7,"rows_kept":7,"merged":[[1,1,2,1],[1,2,1,6]]}
[]
[null,"Strains","Shikimate titer (g/L)"]
[null,null,"Parallel 1","Parallel 2","Parallel 3","Mean value","Error bar"]
[null,"S4",0,0,0,{"$f":"AVERAGE(C4:E4)","v":0},{"$f":"STDEVA(C4:E4)","v":0}]
[null,"D13",0.46,0.29,0.36,{"$f":"AVERAGE(C5:E5)","v":0.36999999999999994},{"$f":"STDEVA(C5:E5)","v":0.08544003745317565}]
[null,"D14",1.36,1.57,1.15,1.36,0.2100000000000006]
[null,"DS7",2,2.24,2.18,2.14,0.12489995996796807]

{"sheet":"Fig. 5d","index":15,"n_rows":8,"n_cols":10,"rows_kept":8,"merged":[[1,1,3,1],[1,2,1,9],[2,2,2,3],[2,4,2,5],[2,6,2,7],[2,8,2,9]]}
[]
[null,"Time (h)","Activity of shikimate kinase I (U/mg)"]
[null,null,"Strain S4",null,"Strain D13",null,"Strain D14",null,"Strain DS7"]
[null,null,"Mean value","Error bar","Mean value","Error bar","Mean value","Error bar","Mean value","Error bar"]
[null,6,0.15,0.11,11.59,1.13,9.45,1.14,8.96,0.46]
[null,12,0.21,0.13,17.48,1.49,7.46,0.94,7.1,0.85]
[null,24,0.19,0.49,12.4,0.85,3.15,0.21,1.83,0.22]
[null,36,0.14,0.54,10.1,1.15,4.59,0.55,1.44,0.46]

{"sheet":"Fig. 5e","index":16,"n_rows":18,"n_cols":14,"rows_kept":18,"merged":[[1,1,1,13],[2,2,2,5],[2,6,2,9],[2,10,2,13]]}
[]
[null,"Strain DS7 with dynamic regulation system (5 L bioreactor)"]
[null,"Time (h)","OD600",{"$nulls":3},"Glucose (g/L)",{"$nulls":3},"Shikimate (g/L)"]
[null,null,"Parallel 1","Parallel 2","Mean value","Error bar","Parallel 1","Parallel 2","Mean value","Error bar","Parallel 1","Parallel 2","Mean value","Error bar"]
[null,0,0.2,0.2,{"$f":"AVERAGE(C5:D5)","v":0.2},{"$f":"AVEDEV(C5:D5)","v":0},40,40,{"$f":"AVERAGE(G5:H5)","v":40},{"$f":"AVEDEV(G5:H5)","v":0},0,0,{"$f":"AVERAGE(K5:L5)","v":0},{"$f":"AVEDEV(K5:L5)","v":0}]
[null,9,1.16,0.95,1.055,0.10499999999999998,39.4,39.5,39.45,0.05000000000000071,0,0,0,0]
[null,12,2.16,1.6,1.8800000000000001,0.28,38.9,39.05,38.974999999999994,0.07499999999999929,0.08,0.37,0.225,0.14500000000000002]
[null,16,2.68,2.21,2.4450000000000003,0.2350000000000001,36.3,39.6,37.95,1.6500000000000021,0.14,0.56,0.35000000000000003,0.21000000000000002]
[null,20,4,3.65,3.825,0.17500000000000004,36.8,37.1,36.95,0.15000000000000213,0.43,0.84,0.635,0.205]
[null,24,7.64,5.45,6.545,1.0949999999999998,35.1,36.8,35.95,0.8499999999999979,0.54,1.07,0.805,0.265]
[null,30,11.81,6.78,9.295,2.515,31.1,32.8,31.95,0.8499999999999979,1.42,1.47,1.4449999999999998,0.025000000000000022]
[null,36,17.81,13.3,15.555,2.254999999999999,22.9,25.04,23.97,1.0700000000000003,2.57,3.03,2.8,0.22999999999999998]
[null,42,21.69,19.34,20.515,1.1750000000000007,15.2,16.72,15.959999999999999,0.7599999999999998,3.21,3.79,3.5,0.29000000000000004]
[null,47,27.6,22.58,25.09,2.5100000000000016,6.4,8.53,7.465,1.0649999999999995,4.78,5.41,5.095000000000001,0.31499999999999995]
[null,47,27.27,22.92,25.095,2.174999999999999,46.9,49.03,47.965,1.0650000000000013,4.78,5.41,5.095000000000001,0.31499999999999995]
[null,57,32.95,29.44,31.195,1.7550000000000008,39,40.93,39.965,0.9649999999999999,6.32,7.87,7.095000000000001,0.7749999999999999]
[null,62,37,31.95,34.475,2.5250000000000004,29.5,30.41,29.955,0.45500000000000007,9.12,9.67,9.395,0.27500000000000036]
[null,72,40,32.95,36.475,3.5249999999999986,10.4,13.5,11.95,1.5499999999999998,12.21,13.03,12.620000000000001,0.40999999999999925]

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[null,"Strains","Shikimate titer (g/L)"]
[null,null,"Control",null,"pbDRC"]
[null,null,"Mean value","Error bar","Mean value","Error bar"]
[null,"MG1655",0.05,0.01788,2.13954,0.10552]
[null,"DH5a",0.19788,0.03187,1.44145,0.07926]
[null,"JM109",0.05663,0.00376,1.07026,0.02506]
[null,"W3110",0.19823,0.03812,1.54737,0.23723]
[null,"ATCC8739",0.06646,0.02501,1.31693,0.12132]
[null,"B0013",0.09275,0.02358,1.64323,0.19788]
[null,"BL21",0.03187,0.01178,1.20518,0.08841]
[null,"HB101",0.14722,0.07101,1.58879,0.05532]

{"sheet":"Fig. 5g","index":18,"n_rows":8,"n_cols":14,"rows_kept":8,"merged":[[1,1,2,1],[1,2,1,6],[1,8,2,8],[1,9,1,13]]}
[]
[null,"Strains","Shikimate titer (g/L)",{"$nulls":5},"Strains","Acetate (g/L)"]
[null,null,"Parallel 1","Parallel 2","Parallel 3","Mean value","Error bar",null,null,"Parallel 1","Parallel 2","Parallel 3","Mean value","Error bar"]
[null,"GS60",0.8,0.75,0.78,{"$f":"AVERAGE(C4:E4)","v":0.7766666666666667},{"$f":"STDEVA(C4:E4)","v":0.025166114784235853},null,"GS60",0,0,0,{"$f":"AVERAGE(J4:L4)","v":0},{"$f":"STDEVA(J4:L4)","v":0}]
[null,"GS4",1.32,1.25,1.17,{"$f":"AVERAGE(C5:E5)","v":1.2466666666666668},{"$f":"STDEVA(C5:E5)","v":0.07505553499465141},null,"GS4",0,0,0,{"$f":"AVERAGE(J5:L5)","v":0},{"$f":"STDEVA(J5:L5)","v":0}]
[null,"GbolA",1.65,2.1,1.88,1.8766666666666667,0.22501851775650236,null,"GbolA",0,0,0,0,0]
[null,"Gfic",1.08,1.24,0.95,1.09,0.1452583904633376,null,"Gfic",0,0,0,0,0]
[null,"-",0.22,0.19,0.25,0.22,0.029999999999999735,null,"-",1.6,1.82,1.3,1.5733333333333333,0.261023626006027]

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[]
[null,"Strains","X1",null,"X2",null,"X3",null,"X4"]
[null,"Time (h)","Mean value","Error bar","Mean value","Error bar","Mean value","Error bar","Mean value","Error bar"]
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[null,0.5,0.0245,1E-3,0.0331,0.004,0.013,1E-3,0.021,0.012]
[null,1,0.03132,0.00509,0.04065,0.01358,0.0275,0.01117,0.0204,0.01549]
[null,1.5,0.055,1E-3,0.044,0.0054,0.0494,0,0.0221,1E-3]
[null,2,0.09645,0.01117,0.05155,0.00177,0.09529,0.00933,0.0371,0.01358]
[null,2.5,0.145,0.015,0.04,1.5E-3,0.124,0.015,0.041,1E-3]
[null,3,0.2288,0.00898,0.06025,0.02305,0.1706,0.02227,0.045,0.01704]
[null,3.5,0.3678,0.004,0.0645,0.023,0.219,0.015,0.054,0.015]
[null,4,0.55532,0.00686,0.0629,1.34E-3,0.29067,0.01273,0.058,0.01336]
[null,4.5,0.784,0.004,0.0741,1.4E-3,0.365,0.016,0.064,0.015]
[null,5,0.9882,0.00608,0.0894,0.02312,0.48275,0.01831,0.08295,0.02171]
[null,5.5,1.114,0.014,0.0745,0.015,0.586,0.004,0.088,0.0164]
[null,6,1.20503,0.02778,0.0861,5.3E-3,0.75328,0.00884,0.0964,0.00891]
[null,6.5,1.2414,0.031,0.096,0.0314,0.864,0.016,0.099,0.0012]
[null,7,1.27078,0.03217,0.11455,0.03125,0.97533,0.01803,0.111,0.01485]
[null,7.5,1.2845,0.035,0.119,1.4E-3,1.061,0.016,0.1224,0.015]
[null,8,1.30865,0.0462,0.12305,0.01061,1.12853,0.01223,0.13135,0.00841]
[null,8.5,1.311,0.047,0.1239,1E-3,1.179,0.0296,0.146,1E-3]
[null,9,1.3202,0.05202,0.13265,0.0186,1.19345,0.04723,0.1616,0.02051]

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[]
[null,"Time (h)","Induction OD"]
[null,null,"Parallel 1","Parallel 2","Parallel 3","Mean value","Error bar"]
[null,4,0.41,0.37,0.39,{"$f":"AVERAGE(C4:E4)","v":0.38999999999999996},{"$f":"STDEVA(C4:E4)","v":0.01999999999999999}]
[null,6,0.79,0.79,0.76,{"$f":"AVERAGE(C5:E5)","v":0.7799999999999999},{"$f":"STDEVA(C5:E5)","v":0.01732050807568879}]
[null,8,1.22,1.17,1.2,1.1966666666666665,0.025166114784235857]
[null,10,1.54,1.42,1.52,1.4933333333333334,0.06429100507328642]
[]
[]
[null,"Time (h)","Final OD"]
[null,null,"Parallel 1","Parallel 2","Parallel 3","Mean value","Error bar"]
[null,4,2.78,2.3,2.5,{"$f":"AVERAGE(C12:E12)","v":2.526666666666667},{"$f":"STDEVA(C12:E12)","v":0.24110855093366831}]
[null,6,5.1,4.98,4.82,{"$f":"AVERAGE(C13:E13)","v":4.966666666666667},{"$f":"STDEVA(C13:E13)","v":0.14047538337136956}]
[null,8,5.15,5.25,5.09,5.163333333333333,0.08082903768654764]
[null,10,5.1,5.4,5.25,5.25,0.15000000000000036]
[]
[]
[null,"Time (h)","Titer (g/L)"]
[null,null,"Parallel 1","Parallel 2","Parallel 3","Mean value","Error bar"]
[null,4,2.99,2.82,2.92,{"$f":"AVERAGE(C20:E20)","v":2.91},{"$f":"STDEVA(C20:E20)","v":0.0854400374531755}]
[null,6,4.1,4.4,4.25,{"$f":"AVERAGE(C21:E21)","v":4.25},{"$f":"STDEVA(C21:E21)","v":0.15000000000000036}]
[null,8,4.04,4.25,4.15,4.1466666666666665,0.10503967504392486]
[null,10,4.07,3.81,3.94,3.94,0.13000000000000012]

{"sheet":"Fig.  6d","index":21,"n_rows":7,"n_cols":10,"rows_kept":7,"merged":[[1,1,2,1],[1,2,1,5],[1,6,1,9]]}
[]
[null,"Glucose vs Xylose","D-xylonate of strain X4 (g/L)",{"$nulls":3},"D-xylonate of control strain (g/L)"]
[null,null,"Parallel 1","Parallel 2","Mean value","Error bar","Parallel 1","Parallel 2","Mean value","Error bar"]
[null,0.5,4.185,3.95262,{"$f":"AVERAGE(C4:D4)","v":4.06881},{"$f":"AVEDEV(C4:D4)","v":0.1161899999999998},4.54776,4.475239999999999,{"$f":"AVERAGE(G4:H4)","v":4.5115},{"$f":"AVEDEV(G4:H4)","v":0.0362600000000004}]
[null,1,4.06325,3.86229,{"$f":"AVERAGE(C5:D5)","v":3.96277},{"$f":"AVEDEV(C5:D5)","v":0.10048000000000012},3.2360200000000003,2.99398,{"$f":"AVERAGE(G5:H5)","v":3.115},{"$f":"AVEDEV(G5:H5)","v":0.12102000000000013}]
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[null,"Xylonate (g/L)",{"$nulls":5},"Xylose consumption (g/L)"]
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[null,24,1.8022,0.14919,1.47497,0.08375,null,24,16.54288,0.19799,16.92358,0.63158]
[null,36,2.65043,0.17509,3.2008,5.96E-3,null,36,15.79674,0.17904,14.99674,0.68064]
[null,48,3.20529,0.13903,4.88791,0.10629,null,48,15.17496,1.05613,13.17496,0.3992]
[null,60,3.11039,0.23705,5.72378,0.54923,null,60,14.95051,0.35763,12.25051,0.111]
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[null,12,2.03,0.26,1.145,0.8849999999999999,26.29,26.02,26.155,0.1349999999999998,47.13,44.86,45.995000000000005,1.1350000000000016,6.41,9.11,7.76,1.3499999999999996,88.87,88.41,88.64,0.23000000000000398]
[null,14,1.09,0,0.545,0.545,29.09,27.25,28.17,0.9199999999999999,27.21,24.78,25.995,1.2149999999999999,7,9.56,8.280000000000001,1.2800000000000002,110.75,108.43,109.59,1.1599999999999966]
[null,14.01,1.09,0,0.545,0.545,29.09,27.25,28.17,0.9199999999999999,97.21,94.78,95.995,1.2149999999999963,7,9.56,8.280000000000001,1.2800000000000002,110.75,108.43,109.59,1.1599999999999966]
[null,23,1.12,0,0.56,0.56,29.7,27.76,28.73,0.9699999999999989,23.38,20.61,21.994999999999997,1.3849999999999998,13.82,17.18,15.5,1.6799999999999997,180.61,177.43,179.02,1.5900000000000034]
[null,24,0.67,0.29,0.48,0.19000000000000003,27.72,25.14,26.43,1.2899999999999991,14.05,11.94,12.995000000000001,1.0550000000000006,12.79,16.58,14.684999999999999,1.8949999999999996,193.06,189.12,191.09,1.9699999999999989]
[null,28,0.87,0,0.435,0.435,24.42,20.44,22.43,1.9900000000000002,0.81,0,0.405,0.405,11.34,12.9,12.120000000000001,0.7800000000000002,199.57,199.3,199.435,0.1349999999999909]

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[null,"Time (h)","RBS"]
[null,null,"B0029",null,"B0031",null,"B0033",null,"B0034",null,"B0064"]
[null,null,"Mean value","Error bar","Mean value","Error bar","Mean value","Error bar","Mean value","Error bar","Mean value","Error bar"]
[null,0,4.56114,0,1.10034,0,1.27625,0,15.28978,0,4.1646,0]
[null,1,632.07862,33.64668,54.09139,5.974,39.8153,3.8399,1226.77555,113.92395,676.68253,77.41017]
[null,3,4565.78641,245.07136,294.96003,40.54604,180.30371,30.48017,7170.94884,89.82424,3399.42695,40.75519]
[null,4,6212.98137,260.96993,382.83516,30.30441,238.15166,7.64006,10253.25673,93.77974,4380.48131,102.15178]
[null,5,7278.51826,390.02658,470.54497,18.0171,321.8412,10.60546,12714.0027,58.97402,4810.08962,158.83701]
[null,6,8582.18841,340.09534,533.15335,21.30649,354.07716,14.1576,14336.56297,408.82522,4976.6216,175.3932]
[null,7,9262.14283,615.65308,646.17171,23.25972,400.90526,33.93668,15334.12768,602.55217,5104.14966,346.33718]
[null,9,9856.55686,529.29733,760.089,40.32478,465.1235,38.19473,15855.143,992.37613,5073.91956,436.81037]
[null,12,10151.1955,496.64861,865.52147,26.0939,513.55468,19.27008,16285.973,804.76973,5291.37304,552.68176]

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[]
[null,"ATC concentration (ng/mL)","Log(ATC)","mCherry",null,"mVenus"]
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[null,100,2,100.00003,1.012,12.87512,3.11785]
[null,50,1.69897,97.45768,2.41916,31.50011,2.23312]
[null,20,1.30103,98.03088,1.61727,77.06116,2.11154]
[null,10,1,98.7845,1.42213,87.47129,2.92623]
[null,0.01,-2,99.18537,2.2236,100,0.22776]
[]
[]
[null,null,"Nonlinear fitting"]
[null,null,"X1","Y1"]
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[]
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[]
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[]
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[]
[null,"30 degrees centigrade"]
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[null,"Time (h)","rpsT P2-(teF)YFP"]
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[null,"mCherry"]
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[]
[]
[null,"GFP"]
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[]
[null,null,"TEVp",null,"TVMVp"]
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[null,"Parallel 1",986.06769,7578.09525,11233.93715,553.60276]
[null,"Parallel 2",819.61745,7972.78445,11887.44655,550.8843]
[null,"Parallel 3",828.86074,8977.99207,10177.84109,615.39201]

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[null,null,"GFP"]
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[null,"Parallel 2",3688.5798,190.46589]
[null,"Parallel 3",3768.0888,167.51656]
[null,"Parallel 4",3509.23092,164.51293]
[null,"Parallel 5",3434.21519,174.36334]
[null,"Parallel 6",3006.39174,204.97993]

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[]
[null,null,"mCherry"]
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[null,"Parallel 1",41.01467,226.41233]
[null,"Parallel 2",42.91443,161.57723]
[null,"Parallel 3",32.36445,258.74644]
[null,"Parallel 4",40.34597,186.57453]
[null,"Parallel 5",43.49845,241.56109]
[null,"Parallel 6",42.71181,178.61721]

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[null,"Fluorescence intensity"]
[null,null,"TEVp","TVMVp","SuMMVp"]
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[null,"summv recognition site",{"v":8426.10103344525,"d":"8426.10"},{"v":4853.218495859134,"d":"4853.22"},{"v":525.3075143100717,"d":"525.31"}]
[]
[null,"Fold change"]
[null,null,"TEVp","TVMVp","SuMMVp"]
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[null,"tvmv recognition site",{"v":1.0000002532715744,"d":"1.00"},{"v":20.292420329775364,"d":"20.29"},{"v":1.4090359603742189,"d":"1.41"}]
[null,"summv recognition site",{"v":1.3332311059895618,"d":"1.33"},{"v":2.31474020994213,"d":"2.31"},{"v":21.38545460320405,"d":"21.39"}]

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[]
[null,"Time (h)","Parallel 1","Parallel 2","Parallel 3","Parallel 4","Parallel 5","Parallel 6","Mean value"]
[null,0,0.0368,0.07154,0.02893,0.07154,0.07878,0.08455,0.05006]
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[null,1.5,0.1332,0.09837,0.14017,0.13538,0.11732,0.12169,0.12325]
[null,2,0.17226,0.2122,0.19573,0.23483,0.23673,0.23519,0.21305]
[null,2.5,0.05862,0.08758,0.1195,0.05323,0.10702,0.11345,0.08941]
[null,3,0.28056,0.32807,0.26493,0.27348,0.2687,0.27085,0.27876]
[null,3.5,0.44132,0.49056,0.44319,0.57686,0.49834,0.4882,0.48607]
[null,4,0.99492,0.91158,0.67647,0.86046,0.70293,0.74051,0.80619]
[null,4.5,0.95951,0.85986,0.91832,0.78425,0.92592,0.79284,0.86545]
[null,5,0.81845,0.72878,0.78455,0.67634,0.705,0.71447,0.74136]
[null,5.5,0.83348,0.81679,0.87357,0.78229,0.88016,0.87839,0.83717]
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[null,"Cell growth  (OD600)"]
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[null,"Shikimate (g/L)"]
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[null,12,0.00439,0.00302,0.02506,0,0.02965,0.01841,0.06299,0,0.03978,0.05501]
[null,24,0.06086,0.01544,0.28597,0,0.25857,0.11316,0.17385,0.03187,0.21663,0.08358]
[null,36,0.07105,0.01297,0.17687,0,0.86318,0.10533,0.39224,0.05663,0.48374,0.11773]
[null,48,0.07957,0.0257,0.0648,0,1.30746,0.15046,0.41018,0.03812,0.97173,0.05609]
[null,60,0.06148,0.0191,0.03758,0,1.86997,0.16269,0.44512,0.05987,1.19007,0.03187]
[null,72,0.05,0.01788,0.02284,0,2.13954,0.10552,0.44418,0.01345,1.29185,0.05328]

{"sheet":"Suppl Fig. 15a","index":41,"n_rows":10,"n_cols":10,"rows_kept":10,"merged":[[2,2,2,9],[3,1,4,1],[3,2,3,3],[3,4,3,5],[3,6,3,7],[3,8,3,9]]}
[]
[null,"Xylose (g/L)"]
[null,null,"Glucose vs Xylose"]
[null,"Time (h)",0.5,null,1,null,1.5,null,2]
[null,null,"Mean value","Error bar","Mean value","Error bar","Mean value","Error bar","Mean value","Error bar"]
[null,0,9.87543,0,9.82069,0,9.75733,0,9.72414,0]
[null,12,9.06681,0.27797,9.26358,0.16977,9.25086,0.23773,9.30905,0.01036]
[null,24,7.61207,0.21091,8.26552,0.25349,8.17241,0.16946,8.17802,0.10911]
[null,36,6.87414,0.20482,7.80345,0.3766,7.5125,0.03414,7.74784,0.27309]
[null,48,4.98233,0.36986,6.46336,0.23707,7.12284,0.35051,7.17759,0.23463]

{"sheet":"Suppl Fig. 15b","index":42,"n_rows":10,"n_cols":10,"rows_kept":10,"merged":[[2,2,2,9],[3,1,4,1],[3,2,3,3],[3,4,3,5],[3,6,3,7],[3,8,3,9]]}
[]
[null,"Glucose (g/L)"]
[null,null,"Glucose vs Xylose"]
[null,"Time (h)",0.5,null,1,null,1.5,null,2]
[null,null,"Mean value","Error bar","Mean value","Error bar","Mean value","Error bar","Mean value","Error bar"]
[null,0,5.79749,0.2,10.05146,0,14.72,0,19.31,0]
[null,12,2.23431,0.01006,7.07594,0.04053,11.77636,0.35888,16.7977,0.11509]
[null,24,0,0,4.02678,0.14083,8.61464,0.23728,13.14561,0.88877]
[null,36,0,0,1.33264,0.1284,6.10879,0.05799,10.90167,0.81835]
[null,48,0,0,0,0,3.50418,0.60416,7.98619,1.04675]

{"sheet":"Suppl Fig. 16","index":43,"n_rows":11,"n_cols":12,"rows_kept":11,"merged":[[1,1,1,5],[1,7,1,11],[2,1,3,1],[2,2,2,3],[2,4,2,5],[2,7,3,7],[2,8,2,9],[2,10,2,11]]}
[]
[null,"Glucose (g/L)",{"$nulls":5},"OD600"]
[null,"Time (h)","Strain XN",null,"Strain XO",null,null,"Time (h)","Strain XN",null,"Strain XO"]
[null,null,"Mean value","Error bar","Mean value","Error bar",null,null,"Mean value","Error bar","Mean value","Error bar"]
[null,0,9.52944,0.02121,9.55239,0.63676,null,0,0.1,0.02,0.1,0.01]
[null,12,4.55,0.2192,5.12561,0.30019,null,12,2.38,0.11,2.18,0.15]
[null,24,3.00715,0.44548,3.41127,0.57885,null,24,5.32,0.22,5.65,0.15]
[null,36,1.0656,0.56569,1.34441,0.86478,null,36,5.77,0.18,5.41,0.19]
[null,48,0.40805,0.17697,0.53706,0.20198,null,48,5.64,0.11,5.55,0.25]
[null,60,0,0,0.16863,0,null,60,5.4,0.14,5.91,0.25]
[null,72,0,0,0.03636,0.17073,null,72,5.17,0.2,6.19,0.35]

{"sheet":"Suppl Fig. 17","index":44,"n_rows":13,"n_cols":7,"rows_kept":13}
[]
[null,"ph value","Parallel 1","Parallel 2","Parallel 3","Mean value","Error bar"]
[null,3,1.0339,1.04025,1.03564,{"$f":"AVERAGE(C3:E3)","v":1.0365966666666666},{"$f":"STDEVA(C3:E3)","v":3.2813157929911206E-3}]
[null,3.5,0.79115,0.76361,0.81125,{"$f":"AVERAGE(C4:E4)","v":0.7886700000000001},{"$f":"STDEVA(C4:E4)","v":0.023916630197417035}]
[null,4,0.60802,0.63418,0.61911,0.6204366666666666,0.013130363031284883]
[null,4.5,0.42108,0.38303,0.38107,0.39505999999999997,0.022555280978076957]
[null,5,0.39404,0.39621,0.4036,0.39795,0.005011895848877954]
[null,5.5,0.36139,0.36221,0.35696,0.36018666666666665,2.8242934219611946E-3]
[null,6,0.63204,0.68255,0.67389,0.6628266666666667,0.02701135008349882]
[null,6.5,0.93043,0.86599,0.85236,0.8829266666666666,0.04169975099845719]
[null,7,1.06276,1.07705,1.05654,1.06545,0.010516277858634232]
[null,7.5,1.31898,1.34031,1.35788,1.3390566666666668,0.019480262660789047]
[null,8,1.5596,1.5549,1.52472,1.5464066666666667,0.018927655251861825]

{"sheet":"Suppl Fig. 18","index":45,"n_rows":7,"n_cols":6,"rows_kept":7,"merged":[[1,1,3,1],[1,2,2,3],[1,4,2,5]]}
[]
[null,"Time (h)","XO",null,"XN"]
[]
[null,null,"Mean value","Error bar","Mean value","Error bar"]
[null,12,{"v":6920000000,"d":"6.92E+09"},{"v":424264000,"d":"4.24E+08"},{"v":5600000000,"d":"5.60E+09"},{"v":537401000,"d":"5.37E+08"}]
[null,24,{"v":4630000000,"d":"4.63E+09"},{"v":1004090000,"d":"1.00E+09"},{"v":760000000,"d":"7.60E+08"},{"v":169706000,"d":"1.70E+08"}]
[null,36,{"v":4610000000,"d":"4.61E+09"},{"v":834386000,"d":"8.34E+08"},{"v":19000000,"d":"1.90E+07"},{"v":14142100,"d":"1.41E+07"}]

{"sheet":"Suppl Fig. 19","index":46,"n_rows":23,"n_cols":6,"rows_kept":23,"merged":[[1,2,1,5],[2,2,2,3],[2,4,2,5],[9,2,9,5],[10,2,10,3],[10,4,10,5],[17,2,17,5],[18,2,18,3],[18,4,18,5]]}
[]
[null,null,"Xylonate (g/L)"]
[null,"Culture temperature",30,null,37]
[null,"Culture medium","Mean value","Error bar","Mean value","Error bar"]
[null,"M9",4.31816,0.71209,6.79211,0.76484]
[null,"1.5X LB",5.63465,0.46796,9.3644,0.87668]
[null,"TB",9.27909,0.35661,13.11063,0.74589]
[]
[]
[null,null,"Acetate (g/L)"]
[null,"Culture temperature",30,null,37]
[null,"Culture medium","Mean value","Error bar","Mean value","Error bar"]
[null,"M9",2.12294,0.58919,2.10798,0.14054]
[null,"1.5X LB",3.07357,0.56892,3.89676,0.19595]
[null,"TB",3.73092,0.18136,4.15187,0.07013]
[]
[]
[null,null,"OD600"]
[null,"Culture temperature",30,null,37]
[null,"Culture medium","Mean value","Error bar","Mean value","Error bar"]
[null,"M9",4.8,0.28853,5.1,0.29314]
[null,"1.5X LB",7.6,0.75786,7,0.54489]
[null,"TB",11,0.12473,9.4,0.54217]