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{"sheet":"W_vs_s.KEGG","index":0,"n_rows":172,"n_cols":8,"rows_kept":172,"merged":[[0,0,0,6]],"flags":["formulas_cached_only"]}
["Supplementary  data 7. KEGG analysis of deregulated genes from RNA-Seq data. "]
["#KEGG_n",110,"KEGG_N",7521]
["#Pathway","ko_ID","DEG","Gene","DEG_all","Gene_all"]
["Valine, leucine and isoleucine degradation","ko00280",1,54,110,7521,"Acaa1b(ENSMUSG00000010651)","K07513"]
["MAPK signaling pathway","ko04010",3,258,110,7521,"Cd14(ENSMUSG00000051439);Mapkapk3(ENSMUSG00000032577);Rac2(ENSMUSG00000033220)","K04391+K04444+K07860"]
["Jak-STAT signaling pathway","ko04630",4,159,110,7521,"Csf2rb(ENSMUSG00000071713);Csf3r(ENSMUSG00000028859);Pik3r5(ENSMUSG00000020901);Ptpn6(ENSMUSG00000004266)","K04738+K05061+K02649+K05697"]
["Arachidonic acid metabolism","ko00590",3,90,110,7521,"Alox5(ENSMUSG00000025701);Cbr2(ENSMUSG00000025150);Hpgds(ENSMUSG00000029919)","K00461+K00081+K01830"]
["Hepatitis C","ko05160",5,138,110,7521,"Ifit1(ENSMUSG00000034459);Irf7(ENSMUSG00000025498);Oas1g(ENSMUSG00000066861);Oas2(ENSMUSG00000032690);Pik3r5(ENSMUSG00000020901)","K14217+K09447+K14216+K14216+K02649"]
["Bile secretion","ko04976",1,72,110,7521,"Abcc3(ENSMUSG00000020865)","K05667"]
["Pancreatic secretion","ko04972",1,106,110,7521,"Bst1(ENSMUSG00000029082)","K18152"]
["Inositol phosphate metabolism","ko00562",1,61,110,7521,"Inpp5d(ENSMUSG00000026288)","K03084"]
["Regulation of actin cytoskeleton","ko04810",7,220,110,7521,"Cd14(ENSMUSG00000051439);Itgb2(ENSMUSG00000000290);Nckap1l(ENSMUSG00000022488);Pik3r5(ENSMUSG00000020901);Rac2(ENSMUSG00000033220);Vav1(ENSMUSG00000034116);Was(ENSMUSG00000031165)","K04391+K06464+K05750+K02649+K07860+K05730+K05747"]
["Salivary secretion","ko04970",2,77,110,7521,"Bst1(ENSMUSG00000029082);Lyz2(ENSMUSG00000069516)","K18152+K13915"]
["Phagosome","ko04145",15,166,110,7521,"Cd14(ENSMUSG00000051439);Cd36(ENSMUSG00000002944);Coro1a(ENSMUSG00000030707);Ctss(ENSMUSG00000038642);Cybb(ENSMUSG00000015340);Fcgr1(ENSMUSG00000015947);Fcgr3(ENSMUSG00000059498);Itgb2(ENSMUSG00000000290);Marco(ENSMUSG00000026390);Msr1(ENSMUSG00000025044);Ncf1(ENSMUSG00000015950);Ncf2(ENSMUSG00000026480);Ncf4(ENSMUSG00000071715);Tlr2(ENSMUSG00000027995);Tlr4(ENSMUSG00000039005)","K04391+K06259+K13882+K01368+K08008+K06498+K16824+K06464+K13884+K06558+K08011+K08010+K08012+K10159+K10160"]
["Amyotrophic lateral sclerosis (ALS)","ko05014",3,52,110,7521,"Casp1(ENSMUSG00000025888);Cyct(ENSMUSG00000056436);Tnfrsf1b(ENSMUSG00000028599)","K01370+K08738+K05141"]
["Estrogen signaling pathway","ko04915",1,99,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Fatty acid degradation","ko00071",1,49,110,7521,"Acaa1b(ENSMUSG00000010651)","K07513"]
["Starch and sucrose metabolism","ko00500",2,57,110,7521,"Hk3(ENSMUSG00000025877);Ugt1a1(ENSMUSG00000089960)","K00844+K00699"]
["Pyrimidine metabolism","ko00240",1,103,110,7521,"Ak9(ENSMUSG00000091415)","K18533"]
["Progesterone-mediated oocyte maturation","ko04914",1,91,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Drug metabolism - other enzymes","ko00983",2,53,110,7521,"Ugt1a1(ENSMUSG00000089960);Xdh(ENSMUSG00000024066)","K00699+K00106"]
["Neurotrophin signaling pathway","ko04722",2,120,110,7521,"Arhgdib(ENSMUSG00000030220);Pik3r5(ENSMUSG00000020901)","K12462+K02649"]
["Inflammatory bowel disease (IBD)","ko05321",2,60,110,7521,"Tlr2(ENSMUSG00000027995);Tlr4(ENSMUSG00000039005)","K10159+K10160"]
["Legionellosis","ko05134",7,59,110,7521,"Casp1(ENSMUSG00000025888);Cd14(ENSMUSG00000051439);Cyct(ENSMUSG00000056436);Itgb2(ENSMUSG00000000290);Naip2(ENSMUSG00000078945);Tlr2(ENSMUSG00000027995);Tlr4(ENSMUSG00000039005)","K01370+K04391+K08738+K06464+K12807+K10159+K10160"]
["TNF signaling pathway","ko04668",4,109,110,7521,"Ccl12(ENSMUSG00000035352);Csf1(ENSMUSG00000014599);Pik3r5(ENSMUSG00000020901);Tnfrsf1b(ENSMUSG00000028599)","K14624+K05453+K02649+K05141"]
["ABC transporters","ko02010",1,47,110,7521,"Abcc3(ENSMUSG00000020865)","K05667"]
["Neuroactive ligand-receptor interaction","ko04080",7,282,110,7521,"Avpr1a(ENSMUSG00000020123);C3ar1(ENSMUSG00000040552);C5ar1(ENSMUSG00000049130);Grik3(ENSMUSG00000001985);Grm4(ENSMUSG00000063239);P2ry13(ENSMUSG00000036362);P2ry6(ENSMUSG00000048779)","K04226+K04009+K04010+K05203+K04607+K08388+K04272"]
["Cytokine-cytokine receptor interaction","ko04060",12,263,110,7521,"Ccl12(ENSMUSG00000035352);Ccl8(ENSMUSG00000009185);Ccr1(ENSMUSG00000025804);Csf1(ENSMUSG00000014599);Csf1r(ENSMUSG00000024621);Csf2rb(ENSMUSG00000071713);Csf3r(ENSMUSG00000028859);Cx3cr1(ENSMUSG00000052336);Cxcl16(ENSMUSG00000018920);Tnfrsf14(ENSMUSG00000042333);Tnfrsf1b(ENSMUSG00000028599);Tnfsf10(ENSMUSG00000039304)","K14624+K16596+K04176+K05453+K05090+K04738+K05061+K04192+K10035+K05152+K05141+K04721"]
["Influenza A","ko05164",10,173,110,7521,"Casp1(ENSMUSG00000025888);Ccl12(ENSMUSG00000035352);Cyct(ENSMUSG00000056436);Irf7(ENSMUSG00000025498);Oas1g(ENSMUSG00000066861);Oas2(ENSMUSG00000032690);Pik3r5(ENSMUSG00000020901);Rsad2(ENSMUSG00000020641);Tlr4(ENSMUSG00000039005);Tnfsf10(ENSMUSG00000039304)","K01370+K14624+K08738+K09447+K14216+K14216+K02649+K15045+K10160+K04721"]
["Melanoma","ko05218",1,72,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["HIF-1 signaling pathway","ko04066",4,116,110,7521,"Cybb(ENSMUSG00000015340);Hk3(ENSMUSG00000025877);Pik3r5(ENSMUSG00000020901);Tlr4(ENSMUSG00000039005)","K08008+K00844+K02649+K10160"]
["B cell receptor signaling pathway","ko04662",6,74,110,7521,"Inpp5d(ENSMUSG00000026288);Lyn(ENSMUSG00000042228);Pik3r5(ENSMUSG00000020901);Ptpn6(ENSMUSG00000004266);Rac2(ENSMUSG00000033220);Vav1(ENSMUSG00000034116)","K03084+K05854+K02649+K05697+K07860+K05730"]
["Pentose and glucuronate interconversions","ko00040",1,39,110,7521,"Ugt1a1(ENSMUSG00000089960)","K00699"]
["Serotonergic synapse","ko04726",1,133,110,7521,"Alox5(ENSMUSG00000025701)","K00461"]
["Cholinergic synapse","ko04725",1,112,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Vasopressin-regulated water reabsorption","ko04962",1,45,110,7521,"Arhgdib(ENSMUSG00000030220)","K12462"]
["Steroid hormone biosynthesis","ko00140",1,89,110,7521,"Ugt1a1(ENSMUSG00000089960)","K00699"]
["Fructose and mannose metabolism","ko00051",1,35,110,7521,"Hk3(ENSMUSG00000025877)","K00844"]
["Central carbon metabolism in cancer","ko05230",2,65,110,7521,"Hk3(ENSMUSG00000025877);Pik3r5(ENSMUSG00000020901)","K00844+K02649"]
["Glycosphingolipid biosynthesis - ganglio series","ko00604",1,15,110,7521,"Hexb(ENSMUSG00000021665)","K12373"]
["MicroRNAs in cancer","ko05206",1,142,110,7521,"Plau(ENSMUSG00000021822)","K01348"]
["Galactose metabolism","ko00052",1,32,110,7521,"Hk3(ENSMUSG00000025877)","K00844"]
["cAMP signaling pathway","ko04024",4,198,110,7521,"Pik3r5(ENSMUSG00000020901);Pld1(ENSMUSG00000027695);Rac2(ENSMUSG00000033220);Vav1(ENSMUSG00000034116)","K02649+K01115+K07860+K05730"]
["Phosphatidylinositol signaling system","ko04070",2,83,110,7521,"Inpp5d(ENSMUSG00000026288);Pik3r5(ENSMUSG00000020901)","K03084+K02649"]
["Renal cell carcinoma","ko05211",1,66,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["ErbB signaling pathway","ko04012",1,88,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Notch signaling pathway","ko04330",1,50,110,7521,"Dtx3l(ENSMUSG00000049502)","K06058"]
["Natural killer cell mediated cytotoxicity","ko04650",10,110,110,7521,"Cd48(ENSMUSG00000015355);Fcer1g(ENSMUSG00000058715);Itgb2(ENSMUSG00000000290);Lcp2(ENSMUSG00000002699);Pik3r5(ENSMUSG00000020901);Ptpn6(ENSMUSG00000004266);Rac2(ENSMUSG00000033220);Tnfsf10(ENSMUSG00000039304);Tyrobp(ENSMUSG00000030579);Vav1(ENSMUSG00000034116)","K06479+K07983+K06464+K07361+K02649+K05697+K07860+K04721+K07992+K05730"]
["Glycolysis / Gluconeogenesis","ko00010",1,72,110,7521,"Hk3(ENSMUSG00000025877)","K00844"]
["Purine metabolism","ko00230",3,181,110,7521,"Ak9(ENSMUSG00000091415);Ampd3(ENSMUSG00000005686);Xdh(ENSMUSG00000024066)","K18533+K01490+K00106"]
["Chagas disease (American trypanosomiasis)","ko05142",8,107,110,7521,"C1qa(ENSMUSG00000036887);C1qb(ENSMUSG00000036905);C1qc(ENSMUSG00000036896);Ccl12(ENSMUSG00000035352);Gna15(ENSMUSG00000034792);Pik3r5(ENSMUSG00000020901);Tlr2(ENSMUSG00000027995);Tlr4(ENSMUSG00000039005)","K03986+K03987+K03988+K14624+K04637+K02649+K10159+K10160"]
["Fc epsilon RI signaling pathway","ko04664",7,73,110,7521,"Fcer1g(ENSMUSG00000058715);Inpp5d(ENSMUSG00000026288);Lcp2(ENSMUSG00000002699);Lyn(ENSMUSG00000042228);Pik3r5(ENSMUSG00000020901);Rac2(ENSMUSG00000033220);Vav1(ENSMUSG00000034116)","K07983+K03084+K07361+K05854+K02649+K07860+K05730"]
["T cell receptor signaling pathway","ko04660",6,105,110,7521,"Cd4(ENSMUSG00000023274);Lcp2(ENSMUSG00000002699);Pik3r5(ENSMUSG00000020901);Ptpn6(ENSMUSG00000004266);Ptprc(ENSMUSG00000026395);Vav1(ENSMUSG00000034116)","K06454+K07361+K02649+K05697+K06478+K05730"]
["Retinol metabolism","ko00830",1,90,110,7521,"Ugt1a1(ENSMUSG00000089960)","K00699"]
["Measles","ko05162",7,144,110,7521,"Irf7(ENSMUSG00000025498);Oas1g(ENSMUSG00000066861);Oas2(ENSMUSG00000032690);Pik3r5(ENSMUSG00000020901);Tlr2(ENSMUSG00000027995);Tlr4(ENSMUSG00000039005);Tnfsf10(ENSMUSG00000039304)","K09447+K14216+K14216+K02649+K10159+K10160+K04721"]
["Long-term depression","ko04730",1,61,110,7521,"Lyn(ENSMUSG00000042228)","K05854"]
["Cytosolic DNA-sensing pathway","ko04623",3,62,110,7521,"Casp1(ENSMUSG00000025888);Irf7(ENSMUSG00000025498);Zbp1(ENSMUSG00000027514)","K01370+K09447+K12965"]
["Herpes simplex infection","ko05168",9,202,110,7521,"Ccl12(ENSMUSG00000035352);Cyct(ENSMUSG00000056436);Ifit1(ENSMUSG00000034459);Irf7(ENSMUSG00000025498);Oas1g(ENSMUSG00000066861);Oas2(ENSMUSG00000032690);Sp100(ENSMUSG00000026222);Tlr2(ENSMUSG00000027995);Tnfrsf14(ENSMUSG00000042333)","K14624+K08738+K14217+K09447+K14216+K14216+K15413+K10159+K05152"]
["Porphyrin and chlorophyll metabolism","ko00860",1,42,110,7521,"Ugt1a1(ENSMUSG00000089960)","K00699"]
["Rheumatoid arthritis","ko05323",5,84,110,7521,"Ccl12(ENSMUSG00000035352);Csf1(ENSMUSG00000014599);Itgb2(ENSMUSG00000000290);Tlr2(ENSMUSG00000027995);Tlr4(ENSMUSG00000039005)","K14624+K05453+K06464+K10159+K10160"]
["Ether lipid metabolism","ko00565",2,43,110,7521,"Pld1(ENSMUSG00000027695);Pld4(ENSMUSG00000052160)","K01115+K16860"]
["Adrenergic signaling in cardiomyocytes","ko04261",1,153,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Nicotinate and nicotinamide metabolism","ko00760",1,32,110,7521,"Bst1(ENSMUSG00000029082)","K18152"]
["Insulin signaling pathway","ko04910",2,144,110,7521,"Hk3(ENSMUSG00000025877);Pik3r5(ENSMUSG00000020901)","K00844+K02649"]
["NOD-like receptor signaling pathway","ko04621",3,58,110,7521,"Casp1(ENSMUSG00000025888);Ccl12(ENSMUSG00000035352);Naip2(ENSMUSG00000078945)","K01370+K14624+K12807"]
["FoxO signaling pathway","ko04068",3,136,110,7521,"Klf2(ENSMUSG00000055148);Pik3r5(ENSMUSG00000020901);Tnfsf10(ENSMUSG00000039304)","K17845+K02649+K04721"]
["Endometrial cancer","ko05213",1,53,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Apoptosis","ko04210",4,84,110,7521,"Csf2rb(ENSMUSG00000071713);Cyct(ENSMUSG00000056436);Pik3r5(ENSMUSG00000020901);Tnfsf10(ENSMUSG00000039304)","K04738+K08738+K02649+K04721"]
["Salmonella infection","ko05132",4,80,110,7521,"Casp1(ENSMUSG00000025888);Cd14(ENSMUSG00000051439);Tlr4(ENSMUSG00000039005);Was(ENSMUSG00000031165)","K01370+K04391+K10160+K05747"]
["Ras signaling pathway","ko04014",5,226,110,7521,"Csf1(ENSMUSG00000014599);Csf1r(ENSMUSG00000024621);Pik3r5(ENSMUSG00000020901);Pld1(ENSMUSG00000027695);Rac2(ENSMUSG00000033220)","K05453+K05090+K02649+K01115+K07860"]
["Choline metabolism in cancer","ko05231",4,102,110,7521,"Pik3r5(ENSMUSG00000020901);Pld1(ENSMUSG00000027695);Rac2(ENSMUSG00000033220);Was(ENSMUSG00000031165)","K02649+K01115+K07860+K05747"]
["Malaria","ko05144",5,48,110,7521,"Ccl12(ENSMUSG00000035352);Cd36(ENSMUSG00000002944);Itgb2(ENSMUSG00000000290);Tlr2(ENSMUSG00000027995);Tlr4(ENSMUSG00000039005)","K14624+K06259+K06464+K10159+K10160"]
["Viral myocarditis","ko05416",3,75,110,7521,"Cyct(ENSMUSG00000056436);Itgb2(ENSMUSG00000000290);Rac2(ENSMUSG00000033220)","K08738+K06464+K07860"]
["Olfactory transduction","ko04740",1,1084,110,7521,"Olfr63(ENSMUSG00000054666)","K04257"]
["Glycosaminoglycan degradation","ko00531",1,21,110,7521,"Hexb(ENSMUSG00000021665)","K12373"]
["mTOR signaling pathway","ko04150",1,63,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Vascular smooth muscle contraction","ko04270",1,127,110,7521,"Avpr1a(ENSMUSG00000020123)","K04226"]
["Prion diseases","ko05020",3,36,110,7521,"C1qa(ENSMUSG00000036887);C1qb(ENSMUSG00000036905);C1qc(ENSMUSG00000036896)","K03986+K03987+K03988"]
["Type II diabetes mellitus","ko04930",2,51,110,7521,"Hk3(ENSMUSG00000025877);Pik3r5(ENSMUSG00000020901)","K00844+K02649"]
["Colorectal cancer","ko05210",3,66,110,7521,"Cyct(ENSMUSG00000056436);Pik3r5(ENSMUSG00000020901);Rac2(ENSMUSG00000033220)","K08738+K02649+K07860"]
["Fatty acid metabolism","ko01212",1,51,110,7521,"Acaa1b(ENSMUSG00000010651)","K07513"]
["Antigen processing and presentation","ko04612",2,77,110,7521,"Cd4(ENSMUSG00000023274);Ctss(ENSMUSG00000038642)","K06454+K01368"]
["Transcriptional misregulation in cancer","ko05202",7,168,110,7521,"Cd14(ENSMUSG00000051439);Csf1r(ENSMUSG00000024621);Fcgr1(ENSMUSG00000015947);Hpgd(ENSMUSG00000031613);Nupr1(ENSMUSG00000030717);Plau(ENSMUSG00000021822);Spi1(ENSMUSG00000002111)","K04391+K05090+K06498+K00069+K15626+K01348+K09438"]
["Signaling pathways regulating pluripotency of stem cells","ko04550",1,139,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Hematopoietic cell lineage","ko04640",8,88,110,7521,"Cd14(ENSMUSG00000051439);Cd33(ENSMUSG00000004609);Cd36(ENSMUSG00000002944);Cd4(ENSMUSG00000023274);Csf1(ENSMUSG00000014599);Csf1r(ENSMUSG00000024621);Csf3r(ENSMUSG00000028859);Fcgr1(ENSMUSG00000015947)","K04391+K06473+K06259+K06454+K05453+K05090+K05061+K06498"]
["Chemical carcinogenesis","ko05204",1,98,110,7521,"Ugt1a1(ENSMUSG00000089960)","K00699"]
["Asthma","ko05310",1,27,110,7521,"Fcer1g(ENSMUSG00000058715)","K07983"]
["Endocytosis","ko04144",3,230,110,7521,"Csf1r(ENSMUSG00000024621);Cyth4(ENSMUSG00000018008);Pld1(ENSMUSG00000027695)","K05090+K18441+K01115"]
["RNA transport","ko03013",1,173,110,7521,"Gm4353(ENSMUSG00000091900)","K14313"]
["Leishmaniasis","ko05140",9,67,110,7521,"Fcgr1(ENSMUSG00000015947);Fcgr3(ENSMUSG00000059498);Itgb2(ENSMUSG00000000290);Ncf1(ENSMUSG00000015950);Ncf2(ENSMUSG00000026480);Ncf4(ENSMUSG00000071715);Ptpn6(ENSMUSG00000004266);Tlr2(ENSMUSG00000027995);Tlr4(ENSMUSG00000039005)","K06498+K16824+K06464+K08011+K08010+K08012+K05697+K10159+K10160"]
["alpha-Linolenic acid metabolism","ko00592",1,24,110,7521,"Acaa1b(ENSMUSG00000010651)","K07513"]
["Peroxisome","ko04146",2,82,110,7521,"Acaa1b(ENSMUSG00000010651);Xdh(ENSMUSG00000024066)","K07513+K00106"]
["Focal adhesion","ko04510",3,208,110,7521,"Pik3r5(ENSMUSG00000020901);Rac2(ENSMUSG00000033220);Vav1(ENSMUSG00000034116)","K02649+K07860+K05730"]
["Glycosphingolipid biosynthesis - globo series","ko00603",1,15,110,7521,"Hexb(ENSMUSG00000021665)","K12373"]
["Base excision repair","ko03410",1,33,110,7521,"Parp3(ENSMUSG00000023249)","K10798"]
["cGMP-PKG signaling pathway","ko04022",1,171,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Ovarian steroidogenesis","ko04913",1,62,110,7521,"Alox5(ENSMUSG00000025701)","K00461"]
["Pancreatic cancer","ko05212",3,66,110,7521,"Pik3r5(ENSMUSG00000020901);Pld1(ENSMUSG00000027695);Rac2(ENSMUSG00000033220)","K02649+K01115+K07860"]
["Hepatitis B","ko05161",5,149,110,7521,"Cyct(ENSMUSG00000056436);Irf7(ENSMUSG00000025498);Pik3r5(ENSMUSG00000020901);Tlr2(ENSMUSG00000027995);Tlr4(ENSMUSG00000039005)","K08738+K09447+K02649+K10159+K10160"]
["Acute myeloid leukemia","ko05221",2,58,110,7521,"Pik3r5(ENSMUSG00000020901);Spi1(ENSMUSG00000002111)","K02649+K09438"]
["VEGF signaling pathway","ko04370",3,62,110,7521,"Mapkapk3(ENSMUSG00000032577);Pik3r5(ENSMUSG00000020901);Rac2(ENSMUSG00000033220)","K04444+K02649+K07860"]
["Rap1 signaling pathway","ko04015",8,218,110,7521,"Csf1(ENSMUSG00000014599);Csf1r(ENSMUSG00000024621);Fyb(ENSMUSG00000022148);Itgb2(ENSMUSG00000000290);Lcp2(ENSMUSG00000002699);Pik3r5(ENSMUSG00000020901);Rac2(ENSMUSG00000033220);Rgs14(ENSMUSG00000052087)","K05453+K05090+K17698+K06464+K07361+K02649+K07860+K17706"]
["Chronic myeloid leukemia","ko05220",1,74,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Biosynthesis of amino acids","ko01230",1,84,110,7521,"Mat1a(ENSMUSG00000037798)","K00789"]
["Glioma","ko05214",1,64,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Axon guidance","ko04360",2,126,110,7521,"Fes(ENSMUSG00000053158);Rac2(ENSMUSG00000033220)","K07527+K07860"]
["Adherens junction","ko04520",3,75,110,7521,"Ptpn6(ENSMUSG00000004266);Rac2(ENSMUSG00000033220);Was(ENSMUSG00000031165)","K05697+K07860+K05747"]
["Oxytocin signaling pathway","ko04921",1,156,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Fat digestion and absorption","ko04975",1,39,110,7521,"Cd36(ENSMUSG00000002944)","K06259"]
["Tuberculosis","ko05152",10,177,110,7521,"Cd14(ENSMUSG00000051439);Coro1a(ENSMUSG00000030707);Ctss(ENSMUSG00000038642);Cyct(ENSMUSG00000056436);Fcer1g(ENSMUSG00000058715);Fcgr1(ENSMUSG00000015947);Fcgr3(ENSMUSG00000059498);Itgb2(ENSMUSG00000000290);Tlr2(ENSMUSG00000027995);Tlr4(ENSMUSG00000039005)","K04391+K13882+K01368+K08738+K07983+K06498+K16824+K06464+K10159+K10160"]
["Carbon metabolism","ko01200",1,115,110,7521,"Hk3(ENSMUSG00000025877)","K00844"]
["Metabolism of xenobiotics by cytochrome P450","ko00980",2,71,110,7521,"Cbr2(ENSMUSG00000025150);Ugt1a1(ENSMUSG00000089960)","K00081+K00699"]
["Pertussis","ko05133",8,74,110,7521,"C1qa(ENSMUSG00000036887);C1qb(ENSMUSG00000036905);C1qc(ENSMUSG00000036896);C4b(ENSMUSG00000073418);Casp1(ENSMUSG00000025888);Cd14(ENSMUSG00000051439);Itgb2(ENSMUSG00000000290);Tlr4(ENSMUSG00000039005)","K03986+K03987+K03988+K03989+K01370+K04391+K06464+K10160"]
["Wnt signaling pathway","ko04310",2,143,110,7521,"Rac2(ENSMUSG00000033220);Sfrp5(ENSMUSG00000018822)","K07860+K02222"]
["Chemokine signaling pathway","ko04062",12,192,110,7521,"Ccl12(ENSMUSG00000035352);Ccl8(ENSMUSG00000009185);Ccr1(ENSMUSG00000025804);Cx3cr1(ENSMUSG00000052336);Cxcl16(ENSMUSG00000018920);Dock2(ENSMUSG00000020143);Lyn(ENSMUSG00000042228);Ncf1(ENSMUSG00000015950);Pik3r5(ENSMUSG00000020901);Rac2(ENSMUSG00000033220);Vav1(ENSMUSG00000034116);Was(ENSMUSG00000031165)","K14624+K16596+K04176+K04192+K10035+K12367+K05854+K08011+K02649+K07860+K05730+K05747"]
["Glycerophospholipid metabolism","ko00564",2,96,110,7521,"Pld1(ENSMUSG00000027695);Pld4(ENSMUSG00000052160)","K01115+K16860"]
["Bacterial invasion of epithelial cells","ko05100",3,78,110,7521,"Hcls1(ENSMUSG00000022831);Pik3r5(ENSMUSG00000020901);Was(ENSMUSG00000031165)","K06106+K02649+K05747"]
["Cysteine and methionine metabolism","ko00270",1,40,110,7521,"Mat1a(ENSMUSG00000037798)","K00789"]
["Huntington's disease","ko05016",1,194,110,7521,"Cyct(ENSMUSG00000056436)","K08738"]
["Carbohydrate digestion and absorption","ko04973",2,47,110,7521,"Hk3(ENSMUSG00000025877);Pik3r5(ENSMUSG00000020901)","K00844+K02649"]
["Sulfur metabolism","ko00920",1,12,110,7521,"Cyct(ENSMUSG00000056436)","K08738"]
["Tight junction","ko04530",2,141,110,7521,"Hcls1(ENSMUSG00000022831);Myh3(ENSMUSG00000020908)","K06106+K10352"]
["Staphylococcus aureus infection","ko05150",11,56,110,7521,"C1qa(ENSMUSG00000036887);C1qb(ENSMUSG00000036905);C1qc(ENSMUSG00000036896);C3ar1(ENSMUSG00000040552);C4b(ENSMUSG00000073418);C5ar1(ENSMUSG00000049130);Cfh(ENSMUSG00000026365);Fcgr1(ENSMUSG00000015947);Fcgr3(ENSMUSG00000059498);Itgb2(ENSMUSG00000000290);Selplg(ENSMUSG00000048163)","K03986+K03987+K03988+K04009+K03989+K04010+K04004+K06498+K16824+K06464+K06544"]
["Alzheimer's disease","ko05010",1,175,110,7521,"Cyct(ENSMUSG00000056436)","K08738"]
["AMPK signaling pathway","ko04152",2,127,110,7521,"Cd36(ENSMUSG00000002944);Pik3r5(ENSMUSG00000020901)","K06259+K02649"]
["Butirosin and neomycin biosynthesis","ko00524",1,5,110,7521,"Hk3(ENSMUSG00000025877)","K00844"]
["Epstein-Barr virus infection","ko05169",4,206,110,7521,"Lyn(ENSMUSG00000042228);Pik3r5(ENSMUSG00000020901);Spi1(ENSMUSG00000002111);Spn(ENSMUSG00000051457)","K05854+K02649+K09438+K06477"]
["Glutamatergic synapse","ko04724",3,113,110,7521,"Grik3(ENSMUSG00000001985);Grm4(ENSMUSG00000063239);Pld1(ENSMUSG00000027695)","K05203+K04607+K01115"]
["Toll-like receptor signaling pathway","ko04620",5,101,110,7521,"Cd14(ENSMUSG00000051439);Irf7(ENSMUSG00000025498);Pik3r5(ENSMUSG00000020901);Tlr2(ENSMUSG00000027995);Tlr4(ENSMUSG00000039005)","K04391+K09447+K02649+K10159+K10160"]
["Amino sugar and nucleotide sugar metabolism","ko00520",2,49,110,7521,"Hexb(ENSMUSG00000021665);Hk3(ENSMUSG00000025877)","K12373+K00844"]
["Prolactin signaling pathway","ko04917",1,77,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Pathways in cancer","ko05200",6,398,110,7521,"Csf1r(ENSMUSG00000024621);Csf3r(ENSMUSG00000028859);Cyct(ENSMUSG00000056436);Pik3r5(ENSMUSG00000020901);Rac2(ENSMUSG00000033220);Spi1(ENSMUSG00000002111)","K05090+K05061+K08738+K02649+K07860+K09438"]
["Thyroid hormone signaling pathway","ko04919",1,118,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Osteoclast differentiation","ko04380",12,123,110,7521,"Csf1(ENSMUSG00000014599);Csf1r(ENSMUSG00000024621);Cybb(ENSMUSG00000015340);Fcgr1(ENSMUSG00000015947);Fcgr3(ENSMUSG00000059498);Lcp2(ENSMUSG00000002699);Ncf1(ENSMUSG00000015950);Ncf2(ENSMUSG00000026480);Ncf4(ENSMUSG00000071715);Pik3r5(ENSMUSG00000020901);Spi1(ENSMUSG00000002111);Tyrobp(ENSMUSG00000030579)","K05453+K05090+K08008+K06498+K16824+K07361+K08011+K08010+K08012+K02649+K09438+K07992"]
["RIG-I-like receptor signaling pathway","ko04622",2,68,110,7521,"Irf7(ENSMUSG00000025498);Isg15(ENSMUSG00000035692)","K09447+K12159"]
["GnRH signaling pathway","ko04912",1,90,110,7521,"Pld1(ENSMUSG00000027695)","K01115"]
["Systemic lupus erythematosus","ko05322",5,116,110,7521,"C1qa(ENSMUSG00000036887);C1qb(ENSMUSG00000036905);C1qc(ENSMUSG00000036896);C4b(ENSMUSG00000073418);Fcgr1(ENSMUSG00000015947)","K03986+K03987+K03988+K03989+K06498"]
["Proteoglycans in cancer","ko05205",6,202,110,7521,"Hcls1(ENSMUSG00000022831);Pik3r5(ENSMUSG00000020901);Plau(ENSMUSG00000021822);Ptpn6(ENSMUSG00000004266);Tlr2(ENSMUSG00000027995);Tlr4(ENSMUSG00000039005)","K06106+K02649+K01348+K05697+K10159+K10160"]
["Hippo signaling pathway","ko04390",1,153,110,7521,"Itgb2(ENSMUSG00000000290)","K06464"]
["Cell adhesion molecules (CAMs)","ko04514",5,155,110,7521,"Cd4(ENSMUSG00000023274);Itgb2(ENSMUSG00000000290);Ptprc(ENSMUSG00000026395);Selplg(ENSMUSG00000048163);Spn(ENSMUSG00000051457)","K06454+K06464+K06478+K06544+K06477"]
["Prostate cancer","ko05215",1,91,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Caffeine metabolism","ko00232",1,6,110,7521,"Xdh(ENSMUSG00000024066)","K00106"]
["Sphingolipid signaling pathway","ko04071",4,124,110,7521,"Fcer1g(ENSMUSG00000058715);Pik3r5(ENSMUSG00000020901);Pld1(ENSMUSG00000027695);Rac2(ENSMUSG00000033220)","K07983+K02649+K01115+K07860"]
["Fc gamma R-mediated phagocytosis","ko04666",11,92,110,7521,"Dock2(ENSMUSG00000020143);Fcgr1(ENSMUSG00000015947);Inpp5d(ENSMUSG00000026288);Lyn(ENSMUSG00000042228);Ncf1(ENSMUSG00000015950);Pik3r5(ENSMUSG00000020901);Pld1(ENSMUSG00000027695);Ptprc(ENSMUSG00000026395);Rac2(ENSMUSG00000033220);Vav1(ENSMUSG00000034116);Was(ENSMUSG00000031165)","K12367+K06498+K03084+K05854+K08011+K02649+K01115+K06478+K07860+K05730+K05747"]
["Lysosome","ko04142",6,123,110,7521,"Cd68(ENSMUSG00000018774);Ctsc(ENSMUSG00000030560);Ctss(ENSMUSG00000038642);Hexb(ENSMUSG00000021665);Laptm5(ENSMUSG00000028581);Slc11a1(ENSMUSG00000026177)","K06501+K01275+K01368+K12373+K12387+K12347"]
["ECM-receptor interaction","ko04512",1,87,110,7521,"Cd36(ENSMUSG00000002944)","K06259"]
["PI3K-Akt signaling pathway","ko04151",6,351,110,7521,"Csf1(ENSMUSG00000014599);Csf1r(ENSMUSG00000024621);Csf3r(ENSMUSG00000028859);Pik3r5(ENSMUSG00000020901);Tlr2(ENSMUSG00000027995);Tlr4(ENSMUSG00000039005)","K05453+K05090+K05061+K02649+K10159+K10160"]
["Aldosterone-regulated sodium reabsorption","ko04960",1,41,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Non-alcoholic fatty liver disease (NAFLD)","ko04932",2,151,110,7521,"Cyct(ENSMUSG00000056436);Pik3r5(ENSMUSG00000020901)","K08738+K02649"]
["Small cell lung cancer","ko05222",2,87,110,7521,"Cyct(ENSMUSG00000056436);Pik3r5(ENSMUSG00000020901)","K08738+K02649"]
["Taste transduction","ko04742",1,63,110,7521,"Grm4(ENSMUSG00000063239)","K04607"]
["Drug metabolism - cytochrome P450","ko00982",1,71,110,7521,"Ugt1a1(ENSMUSG00000089960)","K00699"]
["HTLV-I infection","ko05166",3,272,110,7521,"Itgb2(ENSMUSG00000000290);Pik3r5(ENSMUSG00000020901);Spi1(ENSMUSG00000002111)","K06464+K02649+K09438"]
["NF-kappa B signaling pathway","ko04064",4,105,110,7521,"Cd14(ENSMUSG00000051439);Lyn(ENSMUSG00000042228);Plau(ENSMUSG00000021822);Tlr4(ENSMUSG00000039005)","K04391+K05854+K01348+K10160"]
["Mineral absorption","ko04978",2,45,110,7521,"Ftl1-ps1(ENSMUSG00000062382);Slc11a1(ENSMUSG00000026177)","K13625+K12347"]
["Amoebiasis","ko05146",6,124,110,7521,"Cd14(ENSMUSG00000051439);Gna15(ENSMUSG00000034792);Itgb2(ENSMUSG00000000290);Pik3r5(ENSMUSG00000020901);Tlr2(ENSMUSG00000027995);Tlr4(ENSMUSG00000039005)","K04391+K04637+K06464+K02649+K10159+K10160"]
["Viral carcinogenesis","ko05203",4,207,110,7521,"Irf7(ENSMUSG00000025498);Lyn(ENSMUSG00000042228);Pik3r5(ENSMUSG00000020901);Sp100(ENSMUSG00000026222)","K09447+K05854+K02649+K15413"]
["Parkinson's disease","ko05012",1,145,110,7521,"Cyct(ENSMUSG00000056436)","K08738"]
["Non-small cell lung cancer","ko05223",1,57,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["PPAR signaling pathway","ko03320",2,82,110,7521,"Acaa1b(ENSMUSG00000010651);Cd36(ENSMUSG00000002944)","K07513+K06259"]
["Biosynthesis of unsaturated fatty acids","ko01040",1,26,110,7521,"Acaa1b(ENSMUSG00000010651)","K07513"]
["Platelet activation","ko04611",5,132,110,7521,"Fcer1g(ENSMUSG00000058715);Fermt3(ENSMUSG00000024965);Lcp2(ENSMUSG00000002699);Lyn(ENSMUSG00000042228);Pik3r5(ENSMUSG00000020901)","K07983+K17084+K07361+K05854+K02649"]
["Primary immunodeficiency","ko05340",2,39,110,7521,"Cd4(ENSMUSG00000023274);Ptprc(ENSMUSG00000026395)","K06454+K06478"]
["Adipocytokine signaling pathway","ko04920",2,72,110,7521,"Cd36(ENSMUSG00000002944);Tnfrsf1b(ENSMUSG00000028599)","K06259+K05141"]
["Inflammatory mediator regulation of TRP channels","ko04750",1,127,110,7521,"Pik3r5(ENSMUSG00000020901)","K02649"]
["Calcium signaling pathway","ko04020",2,187,110,7521,"Avpr1a(ENSMUSG00000020123);Gna15(ENSMUSG00000034792)","K04226+K04637"]
["Complement and coagulation cascades","ko04610",9,78,110,7521,"C1qa(ENSMUSG00000036887);C1qb(ENSMUSG00000036905);C1qc(ENSMUSG00000036896);C3ar1(ENSMUSG00000040552);C4b(ENSMUSG00000073418);C5ar1(ENSMUSG00000049130);Cfh(ENSMUSG00000026365);F13a1(ENSMUSG00000039109);Plau(ENSMUSG00000021822)","K03986+K03987+K03988+K04009+K03989+K04010+K04004+K03917+K01348"]
["Toxoplasmosis","ko05145",5,115,110,7521,"Alox5(ENSMUSG00000025701);Cyct(ENSMUSG00000056436);Pik3r5(ENSMUSG00000020901);Tlr2(ENSMUSG00000027995);Tlr4(ENSMUSG00000039005)","K00461+K08738+K02649+K10159+K10160"]
["p53 signaling pathway","ko04115",1,68,110,7521,"Cyct(ENSMUSG00000056436)","K08738"]
["Other glycan degradation","ko00511",1,18,110,7521,"Hexb(ENSMUSG00000021665)","K12373"]
["Ascorbate and aldarate metabolism","ko00053",1,29,110,7521,"Ugt1a1(ENSMUSG00000089960)","K00699"]
["Leukocyte transendothelial migration","ko04670",8,122,110,7521,"Cybb(ENSMUSG00000015340);Itgb2(ENSMUSG00000000290);Ncf1(ENSMUSG00000015950);Ncf2(ENSMUSG00000026480);Ncf4(ENSMUSG00000071715);Pik3r5(ENSMUSG00000020901);Rac2(ENSMUSG00000033220);Vav1(ENSMUSG00000034116)","K08008+K06464+K08011+K08010+K08012+K02649+K07860+K05730"]