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["Supplementary Data 1a Differentially expressed genes between inflamed biopsies and non-inflamed biopsies (linear regression, two-sided t-test, FDR < 0.001, |beta| > 1.5)"]
["beta >0, up regulated in inflamed; beta <0, up regulated in non-inflamed"]
["Beta","SE","WaldTest P","Probe","FDR"]
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[-2.619353,0.2976341,{"v":1.475642e-16,"d":"1.48E-16"},"ENSG00000203859",{"v":6.37206022713e-16,"d":"6.37E-16"}]
[2.136691,0.2442772,{"v":2.142414e-16,"d":"2.14E-16"},"ENSG00000134824",{"v":9.13600843258e-16,"d":"9.14E-16"}]
[2.095828,0.239806,{"v":2.253976e-16,"d":"2.25E-16"},"ENSG00000120738",{"v":9.58331520426e-16,"d":"9.58E-16"}]
[-1.575567,0.180561,{"v":2.479322e-16,"d":"2.48E-16"},"ENSG00000164920",{"v":1.04964050386e-15,"d":"1.05E-15"}]
[1.960947,0.2251584,{"v":2.784955e-16,"d":"2.78E-16"},"ENSG00000179914",{"v":1.17419061939e-15,"d":"1.17E-15"}]
[1.700126,0.1953116,{"v":2.873146e-16,"d":"2.87E-16"},"ENSG00000211940",{"v":1.20959951547e-15,"d":"1.21E-15"}]
[2.240965,0.2574892,{"v":2.904063e-16,"d":"2.90E-16"},"ENSG00000090382",{"v":1.22207868538e-15,"d":"1.22E-15"}]
[2.394949,0.2782017,{"v":5.576294e-16,"d":"5.58E-16"},"ENSG00000159184",{"v":2.29519111289e-15,"d":"2.30E-15"}]
[1.814411,0.2112335,{"v":6.358513e-16,"d":"6.36E-16"},"ENSG00000186417",{"v":2.60856022118e-15,"d":"2.61E-15"}]
[-1.887932,0.2199146,{"v":6.570037e-16,"d":"6.57E-16"},"ENSG00000088386",{"v":2.69187975487e-15,"d":"2.69E-15"}]
[1.546688,0.18051,{"v":7.35412e-16,"d":"7.35E-16"},"ENSG00000145824",{"v":2.99945422134e-15,"d":"3.00E-15"}]
[-1.508609,0.1784862,{"v":1.6284e-15,"d":"1.63E-15"},"ENSG00000188611",{"v":6.43347806487e-15,"d":"6.43E-15"}]
[2.195113,0.2597355,{"v":1.638463e-15,"d":"1.64E-15"},"ENSG00000196735",{"v":6.47234538931e-15,"d":"6.47E-15"}]
[1.571249,0.1861279,{"v":1.748812e-15,"d":"1.75E-15"},"ENSG00000240563",{"v":6.89120627169e-15,"d":"6.89E-15"}]
[-2.015661,0.2394173,{"v":2.041541e-15,"d":"2.04E-15"},"ENSG00000205358",{"v":7.99865579746e-15,"d":"8.00E-15"}]
[-1.594816,0.1941095,{"v":8.039128e-15,"d":"8.04E-15"},"ENSG00000168243",{"v":2.99964659252e-14,"d":"3.00E-14"}]
[-1.901995,0.2347755,{"v":1.729656e-14,"d":"1.73E-14"},"ENSG00000132874",{"v":6.27865783255e-14,"d":"6.28E-14"}]
[-2.130696,0.2637096,{"v":1.997014e-14,"d":"2.00E-14"},"ENSG00000115850",{"v":7.22090118792e-14,"d":"7.22E-14"}]
[-1.654325,0.2049886,{"v":2.125269e-14,"d":"2.13E-14"},"ENSG00000081181",{"v":7.66632986247e-14,"d":"7.67E-14"}]
[-1.566371,0.1948556,{"v":2.622227e-14,"d":"2.62E-14"},"ENSG00000183463",{"v":9.38360977742e-14,"d":"9.38E-14"}]
[2.368821,0.2956554,{"v":3.124941e-14,"d":"3.12E-14"},"ENSG00000163735",{"v":1.11051494605e-13,"d":"1.11E-13"}]
[1.537399,0.1928943,{"v":4.120861e-14,"d":"4.12E-14"},"ENSG00000169908",{"v":1.44726048022e-13,"d":"1.45E-13"}]
[1.788825,0.2244638,{"v":4.143744e-14,"d":"4.14E-14"},"ENSG00000129451",{"v":1.45511928932e-13,"d":"1.46E-13"}]
[2.283967,0.2973027,{"v":2.687492e-13,"d":"2.69E-13"},"ENSG00000215182",{"v":8.85338586202e-13,"d":"8.85E-13"}]
[1.860153,0.2423744,{"v":2.821948e-13,"d":"2.82E-13"},"ENSG00000117322",{"v":9.28037034756e-13,"d":"9.28E-13"}]
[-1.607863,0.2117578,{"v":4.768493e-13,"d":"4.77E-13"},"ENSG00000234155",{"v":1.53757823643e-12,"d":"1.54E-12"}]
[2.514405,0.3352631,{"v":8.629911e-13,"d":"8.63E-13"},"ENSG00000115386",{"v":2.72700254596e-12,"d":"2.73E-12"}]
[-1.584511,0.2124117,{"v":1.11305e-12,"d":"1.11E-12"},"ENSG00000266968",{"v":3.48347689711e-12,"d":"3.48E-12"}]
[-1.511676,0.2273667,{"v":1.561662e-10,"d":"1.56E-10"},"ENSG00000183844",{"v":4.09930927331e-10,"d":"4.10E-10"}]
[-1.543504,0.2352487,{"v":2.601251e-10,"d":"2.60E-10"},"ENSG00000158764",{"v":6.69312220247e-10,"d":"6.69E-10"}]
[1.787282,0.2737147,{"v":3.121173e-10,"d":"3.12E-10"},"ENSG00000187908",{"v":7.98586907503e-10,"d":"7.99E-10"}]
[1.609268,0.2753249,{"v":1.416357e-08,"d":"1.42E-08"},"ENSG00000137077",{"v":3.1500656342e-08,"d":"3.15E-08"}]
[-1.608333,0.2824096,{"v":3.134788e-08,"d":"3.13E-08"},"ENSG00000015520",{"v":6.76673543951e-08,"d":"6.77E-08"}]
[1.537128,0.2721568,{"v":4.010505e-08,"d":"4.01E-08"},"ENSG00000166828",{"v":8.57527348483e-08,"d":"8.58E-08"}]
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[1.905802,0.3464441,{"v":8.565737e-08,"d":"8.57E-08"},"ENSG00000172023",{"v":1.77886631847e-07,"d":"1.78E-07"}]
[1.611204,0.2995495,{"v":1.59263e-07,"d":"1.59E-07"},"ENSG00000125740",{"v":3.22906911976e-07,"d":"3.23E-07"}]

{"sheet":"Supplementary Data 1.b","index":1,"n_rows":45,"n_cols":3,"rows_kept":45,"flags":["formulas_cached_only"]}
["Supplementary Data 1b, REACTOME top annotations for genes differentially expressed between inflamed and non-inflamed tissues (P values were obtained from two-sided Wilcoxon test)"]
["Up-regulated genes in inflammation"]
["gene_set_id","gene_set_name","p-value"]
["REACTOME:R-HSA-6785807","Interleukin-4 and 13 signaling",{"v":4.53777064420295e-96,"d":"4.54E-96"}]
["REACTOME:R-HSA-381753","Olfactory Signaling Pathway",{"v":7.29316136597094e-90,"d":"7.29E-90"}]
["REACTOME:R-HSA-380108","Chemokine receptors bind chemokines",{"v":4.82650860955816e-60,"d":"4.83E-60"}]
["REACTOME:R-HSA-168256","Immune System",{"v":2.30111096011768e-57,"d":"2.30E-57"}]
["REACTOME:R-HSA-418555","G alpha (s) signalling events",{"v":3.39136397970404e-55,"d":"3.39E-55"}]
["REACTOME:R-HSA-375276","Peptide ligand-binding receptors",{"v":7.94201301145777e-53,"d":"7.94E-53"}]
["REACTOME:R-HSA-1442490","Collagen degradation",{"v":3.47183604339362e-51,"d":"3.47E-51"}]
["REACTOME:R-HSA-1592389","Activation of Matrix Metalloproteinases",{"v":1.40327500261641e-50,"d":"1.40E-50"}]
["REACTOME:R-HSA-1474228","Degradation of the extracellular matrix",{"v":1.7807171448707e-48,"d":"1.78E-48"}]
["REACTOME:R-HSA-1474244","Extracellular matrix organization",{"v":2.31306416720153e-48,"d":"2.31E-48"}]
["REACTOME:R-HSA-5621480","Dectin-2 family",{"v":1.4042283935327e-47,"d":"1.40E-47"}]
["REACTOME:R-HSA-373076","Class A/1 (Rhodopsin-like receptors)",{"v":2.27545360743018e-45,"d":"2.28E-45"}]
["REACTOME:R-HSA-449147","Signaling by Interleukins",{"v":3.87849769336587e-44,"d":"3.88E-44"}]
["REACTOME:R-HSA-168249","Innate Immune System",{"v":7.50889028915708e-43,"d":"7.51E-43"}]
["REACTOME:R-HSA-381426","Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)",{"v":1.47894178894237e-42,"d":"1.48E-42"}]
["REACTOME:R-HSA-500792","GPCR ligand binding",{"v":2.87565265678904e-39,"d":"2.88E-39"}]
["REACTOME:R-HSA-2022090","Assembly of collagen fibrils and other multimeric structures",{"v":1.2946353579934e-38,"d":"1.29E-38"}]
["REACTOME:R-HSA-6783783","Interleukin-10 signaling",{"v":3.44484828319413e-38,"d":"3.44E-38"}]
["REACTOME:R-HSA-109582","Hemostasis",{"v":1.07725340081772e-36,"d":"1.08E-36"}]
["REACTOME:R-HSA-162599","Late Phase of HIV Life Cycle",{"v":1.69735637362407e-36,"d":"1.70E-36"}]
["Down-regulated genes in inflammation"]
["gene_set_id","gene_set_name","p-value"]
["REACTOME:R-HSA-211859","Biological oxidations",{"v":7.97709369216991e-105,"d":"7.98E-105"}]
["REACTOME:R-HSA-425407","SLC-mediated transmembrane transport",{"v":7.5487001744662e-96,"d":"7.55E-96"}]
["REACTOME:R-HSA-382551","Transport of small molecules",{"v":3.57471298783641e-94,"d":"3.57E-94"}]
["REACTOME:R-HSA-156580","Phase II - Conjugation of compounds",{"v":1.71394274185093e-90,"d":"1.71E-90"}]
["REACTOME:R-HSA-1430728","Metabolism",{"v":3.30576771856197e-79,"d":"3.31E-79"}]
["REACTOME:R-HSA-211945","Phase I - Functionalization of compounds",{"v":8.84683608287049e-74,"d":"8.85E-74"}]
["REACTOME:R-HSA-556833","Metabolism of lipids",{"v":8.64615888511784e-72,"d":"8.65E-72"}]
["REACTOME:R-HSA-5619102","SLC transporter disorders",{"v":5.06676034334305e-71,"d":"5.07E-71"}]
["REACTOME:R-HSA-196854","Metabolism of vitamins and cofactors",{"v":1.10787993140811e-69,"d":"1.11E-69"}]
["REACTOME:R-HSA-425393","Transport of inorganic cations/anions and amino acids/oligopeptides",{"v":8.56587910400566e-68,"d":"8.57E-68"}]
["REACTOME:R-HSA-2142753","Arachidonic acid metabolism",{"v":2.56875039294397e-67,"d":"2.57E-67"}]
["REACTOME:R-HSA-425366","Transport of bile salts and organic acids",{"v":1.82746446138112e-66,"d":"1.83E-66"}]
["REACTOME:R-HSA-6806667","Metabolism of fat-soluble vitamins",{"v":7.60014688837356e-64,"d":"7.60E-64"}]
["REACTOME:R-HSA-211897","Cytochrome P450 - arranged by substrate type",{"v":9.47838540253161e-57,"d":"9.48E-57"}]
["REACTOME:R-HSA-2187338","Visual phototransduction",{"v":1.31637846434315e-54,"d":"1.32E-54"}]
["REACTOME:R-HSA-156588","Glucuronidation",{"v":1.66672018040347e-53,"d":"1.67E-53"}]
["REACTOME:R-HSA-5423646","Aflatoxin activation and detoxification",{"v":7.52855157398227e-53,"d":"7.53E-53"}]
["REACTOME:R-HSA-1640170","Cell Cycle",{"v":1.67286611452385e-49,"d":"1.67E-49"}]
["REACTOME:R-HSA-392499","Metabolism of proteins",{"v":1.51559902529795e-46,"d":"1.52E-46"}]
["REACTOME:R-HSA-390918","Peroxisomal lipid metabolism",{"v":3.30541770180892e-46,"d":"3.31E-46"}]