{"text_format":"3","workbook":"xlsx","n_sheets":1,"sheets":["Supp_Data_14"],"not_rendered":{"defined_names":1},"read":"whole","date_system":"1900"}

{"sheet":"Supp_Data_14","index":0,"n_rows":243684,"n_cols":14,"rows_kept":4500,"cut":true,"bounds":{"rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0}}
["Supplementary Data 14: Differential Gene Correlation Analysis of sDSS-protein correlations of BCP-ALL and T-ALL cell lines"]
[]
["Protein","Drug Name","B_cor","B_pVal","T_cor","T_pVal","zScoreDiff","pValDiff","empPVals","pValDiff_adj","Classes","Mechanism Targets","Putative Target Protein(s)","Drug Class"]
["TXNDC9","SN_38",0.749,{"v":1.63E-5,"d":"1.63E-05"},-0.713,0.00194,-5.33,{"v":9.83E-8,"d":"9.83E-08"},{"v":2.5e-07,"d":"2.50E-07"},0.0293,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["TXNDC9","Raltitrexed",0.81,{"v":9.26e-07,"d":"9.26E-07"},-0.62,0.0104,-5.29,{"v":1.19e-07,"d":"1.19E-07"},{"v":2.5e-07,"d":"2.50E-07"},0.0293,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["CSTF2","Imiquimod",0.0553,0.793,-0.968,{"v":8.52e-10,"d":"8.52E-10"},-6.04,{"v":1.5E-9,"d":"1.50E-09"},{"v":2.49e-07,"d":"2.49E-07"},0.0299,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["CDC7","Cytarabine",0.751,{"v":1.51e-05,"d":"1.51E-05"},-0.812,1.35E-4,-6.02,{"v":1.71e-09,"d":"1.71E-09"},{"v":2.49e-07,"d":"2.49E-07"},0.0299,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["DDX5","8_amino_adenosine",0.487,0.0136,-0.916,{"v":6.39e-07,"d":"6.39E-07"},-5.99,{"v":2.13e-09,"d":"2.13E-09"},{"v":2.49e-07,"d":"2.49E-07"},0.0299,"+/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["DIAPH2","Losmapimod",0.174,0.405,-0.943,{"v":4.36E-8,"d":"4.36E-08"},-5.55,{"v":2.8e-08,"d":"2.80E-08"},{"v":4.98e-07,"d":"4.98E-07"},0.0359,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["DNA2","Cytarabine",0.664,0.000294,-0.814,1.22E-4,-5.55,{"v":2.91e-08,"d":"2.91E-08"},{"v":4.98e-07,"d":"4.98E-07"},0.0359,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["DIAPH2","Mitomycin_C",0.262,0.206,-0.927,{"v":2.51e-07,"d":"2.51E-07"},-5.44,{"v":5.38e-08,"d":"5.38E-08"},{"v":7.48e-07,"d":"7.48E-07"},0.0384,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["CSTF2","IOX_2",0.289,0.161,-0.92,{"v":4.39E-7,"d":"4.39E-07"},-5.4,{"v":6.67e-08,"d":"6.67E-08"},{"v":7.48e-07,"d":"7.48E-07"},0.0384,"0/-","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["RELL1","Amsacrine",-0.728,{"v":3.66e-05,"d":"3.66E-05"},0.841,{"v":4.53e-05,"d":"4.53E-05"},6.14,{"v":8.14e-10,"d":"8.14E-10"},{"v":2.49e-07,"d":"2.49E-07"},0.059,"-/+","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["RAD51","Gemcitabine",0.736,{"v":2.8E-5,"d":"2.80E-05"},-0.75,8.12E-4,-5.47,{"v":4.44e-08,"d":"4.44E-08"},{"v":7.48e-07,"d":"7.48E-07"},0.059,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["RELL1","Cytarabine.Idarubicin",-0.713,{"v":6.23e-05,"d":"6.23E-05"},0.761,0.000625,5.41,{"v":6.38e-08,"d":"6.38E-08"},{"v":9.97e-07,"d":"9.97E-07"},0.059,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["RELL1","Etoposide",-0.573,0.00275,0.844,{"v":3.98e-05,"d":"3.98E-05"},5.39,{"v":6.97e-08,"d":"6.97E-08"},{"v":9.97e-07,"d":"9.97E-07"},0.059,"-/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["RAD51","Pemetrexed",0.726,{"v":3.95e-05,"d":"3.95E-05"},-0.746,0.000909,-5.39,{"v":7.18e-08,"d":"7.18E-08"},{"v":9.97e-07,"d":"9.97E-07"},0.059,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["RELL1","Cytarabine",-0.647,0.00047,0.803,1.83E-4,5.36,{"v":8.16e-08,"d":"8.16E-08"},{"v":9.97e-07,"d":"9.97E-07"},0.059,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ZNF507","Tozasertib",0.81,{"v":9.06e-07,"d":"9.06E-07"},-0.587,0.0168,-5.15,{"v":2.61e-07,"d":"2.61E-07"},{"v":1.25e-06,"d":"1.25E-06"},0.078,"+/-","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["TRIO","Prexasertib",0.474,0.0167,-0.854,{"v":2.5e-05,"d":"2.50E-05"},-5.11,{"v":3.23e-07,"d":"3.23E-07"},{"v":1.75E-6,"d":"1.75E-06"},0.078,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["VAC14","GSK_461364",-0.585,0.00213,0.803,0.000177,5.08,{"v":3.7E-7,"d":"3.70E-07"},{"v":1.75E-6,"d":"1.75E-06"},0.078,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["TXNDC9","Cytarabine",0.742,{"v":2.2e-05,"d":"2.20E-05"},-0.676,0.00405,-5.08,{"v":3.85e-07,"d":"3.85E-07"},{"v":1.75E-6,"d":"1.75E-06"},0.078,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ZNF185","A_1155463",0.602,1.47E-3,-0.784,0.000324,-5.01,{"v":5.53e-07,"d":"5.53E-07"},{"v":2e-06,"d":"2.00E-06"},0.078,"+/-","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2","Apoptotic modulator"]
["TXNDC9","Pemetrexed",0.778,{"v":4.78E-6,"d":"4.78E-06"},-0.609,0.0123,-4.99,{"v":5.99E-7,"d":"5.99E-07"},{"v":2e-06,"d":"2.00E-06"},0.078,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["DST","PF_670462",0.737,{"v":2.6e-05,"d":"2.60E-05"},-0.719,0.00169,-5.29,{"v":1.22e-07,"d":"1.22E-07"},{"v":1.99E-6,"d":"1.99E-06"},0.0797,"+/-","CK1epsilon and CK1delta inhibitor","CSNK1D;CSNK1E","Kinase inhibitor"]
["DIAPH2","Perifosine",0.136,0.518,-0.937,{"v":8.86e-08,"d":"8.86E-08"},-5.29,{"v":1.23E-7,"d":"1.23E-07"},{"v":1.99E-6,"d":"1.99E-06"},0.0797,"0/-","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["IDH3A","Sitravatinib",0.535,0.00586,-0.858,{"v":2.08e-05,"d":"2.08E-05"},-5.39,{"v":7.16e-08,"d":"7.16E-08"},{"v":1.25e-06,"d":"1.25E-06"},0.0826,"+/-","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["MIS18A","Prexasertib",0.79,{"v":2.67e-06,"d":"2.67E-06"},-0.671,0.00444,-5.38,{"v":7.29e-08,"d":"7.29E-08"},{"v":1.25e-06,"d":"1.25E-06"},0.0826,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["KLHL26","Mitomycin_C",0.204,0.328,-0.931,{"v":1.67E-7,"d":"1.67E-07"},-5.35,{"v":8.68e-08,"d":"8.68E-08"},{"v":1.5E-6,"d":"1.50E-06"},0.0826,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["MIS18A","Gemcitabine",0.659,0.000342,-0.783,0.000334,-5.27,{"v":1.35E-7,"d":"1.35E-07"},{"v":2.24e-06,"d":"2.24E-06"},0.0826,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["LAT2","AZD_5438",-0.549,0.00452,0.83,{"v":6.97E-5,"d":"6.97E-05"},5.16,{"v":2.51e-07,"d":"2.51E-07"},{"v":2.24e-06,"d":"2.24E-06"},0.0826,"-/+","CDK1, 2, 9 inhibitor","CDK1;CDK2;CDK9","Kinase inhibitor"]
["MAGED1","Onalespib",0.63,7.36E-4,-0.779,0.000373,-5.1,{"v":3.34E-7,"d":"3.34E-07"},{"v":2.24e-06,"d":"2.24E-06"},0.0826,"+/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["KLHL26","Losmapimod",0.188,0.368,-0.92,{"v":4.5e-07,"d":"4.50E-07"},-5.09,{"v":3.61e-07,"d":"3.61E-07"},{"v":2.49e-06,"d":"2.49E-06"},0.0826,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["IMMP1L","Tamatinib",0.523,0.00734,-0.826,{"v":8.11e-05,"d":"8.11E-05"},-5.02,{"v":5.25e-07,"d":"5.25E-07"},{"v":3.49E-6,"d":"3.49E-06"},0.0826,"+/-","SYK inhibitor","SYK","Kinase inhibitor"]
["MCPH1","Cytarabine",0.786,{"v":3.19E-6,"d":"3.19E-06"},-0.598,0.0144,-5.01,{"v":5.52e-07,"d":"5.52E-07"},{"v":3.49E-6,"d":"3.49E-06"},0.0826,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["KNSTRN","Cytarabine",0.723,{"v":4.5e-05,"d":"4.50E-05"},-0.682,0.00361,-4.99,{"v":5.99E-7,"d":"5.99E-07"},{"v":3.49E-6,"d":"3.49E-06"},0.0826,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["LDAH","Losmapimod",0.341,0.0948,-0.883,{"v":5.94e-06,"d":"5.94E-06"},-4.99,{"v":6.18e-07,"d":"6.18E-07"},{"v":3.49E-6,"d":"3.49E-06"},0.0826,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["ITPR3","Foretinib",-0.719,{"v":5.16e-05,"d":"5.16E-05"},0.685,0.00343,4.98,{"v":6.25e-07,"d":"6.25E-07"},{"v":3.49E-6,"d":"3.49E-06"},0.0826,"-/+","MET, VEGFR2 inhibitor","MET;KDR","Kinase inhibitor"]
["KLHL26","Vinblastine",0.296,0.151,-0.893,{"v":3.18E-6,"d":"3.18E-06"},-4.98,{"v":6.33e-07,"d":"6.33E-07"},{"v":3.49E-6,"d":"3.49E-06"},0.0826,"0/-","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["LRR1","Cytarabine",0.593,1.8E-3,-0.785,0.000313,-4.98,{"v":6.48e-07,"d":"6.48E-07"},{"v":3.49E-6,"d":"3.49E-06"},0.0826,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["KNSTRN","Pemetrexed",0.825,{"v":3.98e-07,"d":"3.98E-07"},-0.508,0.0448,-4.95,{"v":7.52e-07,"d":"7.52E-07"},{"v":3.49E-6,"d":"3.49E-06"},0.0826,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["CALD1","AMG319",0.484,0.0141,-0.949,{"v":2.02e-08,"d":"2.02E-08"},-6.73,{"v":1.73e-11,"d":"1.73E-11"},{"v":2.49e-07,"d":"2.49E-07"},0.0858,"+/-","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["ARIH2","Losmapimod",0.286,0.165,-0.939,{"v":6.79e-08,"d":"6.79E-08"},-5.8,{"v":6.71e-09,"d":"6.71E-09"},{"v":4.98e-07,"d":"4.98E-07"},0.0858,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["ACO2","PS_1145",-0.235,0.257,0.937,{"v":9.41e-08,"d":"9.41E-08"},5.57,{"v":2.54e-08,"d":"2.54E-08"},{"v":7.48e-07,"d":"7.48E-07"},0.0858,"0/+","IKK-2 inhibitor","IKBKB","Kinase inhibitor"]
["SORBS2","AZD3965",0.116,0.581,0.974,{"v":2.15e-10,"d":"2.15E-10"},5.84,{"v":5.18e-09,"d":"5.18E-09"},{"v":4.98e-07,"d":"4.98E-07"},0.0862,"0/+","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["SIRT1","Prexasertib",0.752,{"v":1.47E-5,"d":"1.47E-05"},-0.749,0.000835,-5.57,{"v":2.56e-08,"d":"2.56E-08"},{"v":4.98e-07,"d":"4.98E-07"},0.0862,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["TIMM29","Perifosine",0.277,0.181,-0.925,{"v":2.89e-07,"d":"2.89E-07"},-5.45,{"v":4.94e-08,"d":"4.94E-08"},{"v":9.97e-07,"d":"9.97E-07"},0.0862,"0/-","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["SLC25A29","Losmapimod",0.498,0.0113,-0.876,{"v":8.71e-06,"d":"8.71E-06"},-5.44,{"v":5.24e-08,"d":"5.24E-08"},{"v":9.97e-07,"d":"9.97E-07"},0.0862,"+/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["RAD51","Cytarabine",0.646,0.000489,-0.786,0.000305,-5.23,{"v":1.7e-07,"d":"1.70E-07"},{"v":2.24e-06,"d":"2.24E-06"},0.0885,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["PWP1","GSK_1070916",0.39,0.0538,-0.889,{"v":4.25E-6,"d":"4.25E-06"},-5.22,{"v":1.77e-07,"d":"1.77E-07"},{"v":2.24e-06,"d":"2.24E-06"},0.0885,"0/-","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["SAP30L","Mitomycin_C",-0.342,0.0943,0.894,{"v":3.09e-06,"d":"3.09E-06"},5.13,{"v":2.82e-07,"d":"2.82E-07"},{"v":2.49e-06,"d":"2.49E-06"},0.0885,"0/+","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["RAB15","PS_1145",-0.549,0.00448,0.827,{"v":7.7e-05,"d":"7.70E-05"},5.13,{"v":2.82e-07,"d":"2.82E-07"},{"v":2.49e-06,"d":"2.49E-06"},0.0885,"-/+","IKK-2 inhibitor","IKBKB","Kinase inhibitor"]
["FGFR1OP","Clofarabine",0.399,0.0482,-0.931,{"v":1.65e-07,"d":"1.65E-07"},-5.97,{"v":2.35e-09,"d":"2.35E-09"},{"v":4.98e-07,"d":"4.98E-07"},0.0964,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["EPB41L5","Floxuridine",0.51,0.00926,-0.877,{"v":8.23e-06,"d":"8.23E-06"},-5.5,{"v":3.76e-08,"d":"3.76E-08"},{"v":1.5E-6,"d":"1.50E-06"},0.0964,"+/-","Antimetabolite, Analog of 5-fluorouracil","TYMS","Conv.Chemo"]
["GMNN","Gemcitabine",0.622,0.000893,-0.819,1.03E-4,-5.38,{"v":7.31e-08,"d":"7.31E-08"},{"v":1.5E-6,"d":"1.50E-06"},0.0964,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["EIF4G2","Cytarabine",0.773,{"v":5.89e-06,"d":"5.89E-06"},-0.684,3.48E-3,-5.33,{"v":9.84e-08,"d":"9.84E-08"},{"v":1.99E-6,"d":"1.99E-06"},0.0964,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["FGFR1OP","Topotecan",0.402,0.0465,-0.893,{"v":3.26e-06,"d":"3.26E-06"},-5.32,{"v":1.03E-7,"d":"1.03E-07"},{"v":1.99E-6,"d":"1.99E-06"},0.0964,"+/-","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["GMNN","Cytarabine.Idarubicin",0.626,0.000807,-0.807,1.55E-4,-5.3,{"v":1.14E-7,"d":"1.14E-07"},{"v":2.24e-06,"d":"2.24E-06"},0.0964,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["FGFR1OP","Cytarabine",0.383,0.0591,-0.892,{"v":3.44e-06,"d":"3.44E-06"},-5.24,{"v":1.57e-07,"d":"1.57E-07"},{"v":2.74E-6,"d":"2.74E-06"},0.0964,"0/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["FGFR1OP","Gemcitabine",0.431,0.0314,-0.879,{"v":7.52E-6,"d":"7.52E-06"},-5.23,{"v":1.66E-7,"d":"1.66E-07"},{"v":2.74E-6,"d":"2.74E-06"},0.0964,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["FGFR1OP","SN_38",0.456,0.0219,-0.869,{"v":1.26E-5,"d":"1.26E-05"},-5.21,{"v":1.94e-07,"d":"1.94E-07"},{"v":2.74E-6,"d":"2.74E-06"},0.0964,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["GMNN","Cytarabine",0.685,0.000157,-0.753,7.67E-4,-5.2,{"v":2.03E-7,"d":"2.03E-07"},{"v":2.74E-6,"d":"2.74E-06"},0.0964,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["WSB1","Losmapimod",-0.259,0.21,0.897,{"v":2.51e-06,"d":"2.51E-06"},4.92,{"v":8.57e-07,"d":"8.57E-07"},{"v":2.75e-06,"d":"2.75E-06"},0.0965,"0/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["ZNF518B","ODM_201",0.503,0.0103,-0.821,{"v":9.73e-05,"d":"9.73E-05"},-4.9,{"v":9.7e-07,"d":"9.70E-07"},{"v":3.25e-06,"d":"3.25E-06"},0.0975,"+/-","AR antagonist","AR","Hormone therapy"]
["ZEB1","Quizartinib",-0.691,0.00013,0.692,2.98E-3,4.87,{"v":1.14e-06,"d":"1.14E-06"},{"v":3.99e-06,"d":"3.99E-06"},0.0975,"-/+","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["WDR62","Cladribine",0.704,{"v":8.63e-05,"d":"8.63E-05"},-0.676,0.00402,-4.85,{"v":1.23e-06,"d":"1.23E-06"},{"v":4.49e-06,"d":"4.49E-06"},0.0975,"+/-","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["WASHC4","Cytarabine",-0.598,0.00159,0.764,0.000563,4.85,{"v":1.23e-06,"d":"1.23E-06"},{"v":4.49e-06,"d":"4.49E-06"},0.0975,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["WDR62","Niraparib",0.667,0.000275,-0.708,2.16E-3,-4.82,{"v":1.42E-6,"d":"1.42E-06"},{"v":4.99e-06,"d":"4.99E-06"},0.0975,"+/-","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["TXNDC9","Cytarabine.Idarubicin",0.737,{"v":2.6e-05,"d":"2.60E-05"},-0.628,0.00916,-4.81,{"v":1.49e-06,"d":"1.49E-06"},{"v":4.99e-06,"d":"4.99E-06"},0.0975,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["ZNF292","Belinostat",-0.533,0.00608,0.796,0.000228,4.81,{"v":1.55E-6,"d":"1.55E-06"},{"v":4.99e-06,"d":"4.99E-06"},0.0975,"-/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["ZNF77","Perifosine",-0.106,0.613,-0.945,{"v":3.38e-08,"d":"3.38E-08"},-4.8,{"v":1.59E-6,"d":"1.59E-06"},{"v":4.99e-06,"d":"4.99E-06"},0.0975,"0/-","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["CDCA4","Tipifarnib",0.532,0.00625,-0.84,{"v":4.62e-05,"d":"4.62E-05"},-5.19,{"v":2.14e-07,"d":"2.14E-07"},{"v":2.99e-06,"d":"2.99E-06"},0.106,"+/-","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["CDR2","Prexasertib",0.616,0.00105,-0.798,2.14E-4,-5.17,{"v":2.28E-7,"d":"2.28E-07"},{"v":3.24e-06,"d":"3.24E-06"},0.106,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ASB7","Losmapimod",-0.48,0.0151,0.87,{"v":1.21e-05,"d":"1.21E-05"},5.3,{"v":1.15E-7,"d":"1.15E-07"},{"v":1.74e-06,"d":"1.74E-06"},0.11,"-/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["CASP10","BX_912",-0.64,0.00057,0.797,0.000215,5.29,{"v":1.24E-7,"d":"1.24E-07"},{"v":1.99E-6,"d":"1.99E-06"},0.11,"-/+","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["BUB1","Niraparib",0.561,0.00353,-0.836,{"v":5.57e-05,"d":"5.57E-05"},-5.26,{"v":1.43E-7,"d":"1.43E-07"},{"v":2.24e-06,"d":"2.24E-06"},0.11,"+/-","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["CBL","AZD7762",-0.714,{"v":6.17e-05,"d":"6.17E-05"},0.738,0.00111,5.26,{"v":1.44e-07,"d":"1.44E-07"},{"v":2.24e-06,"d":"2.24E-06"},0.11,"-/+","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["KIAA1191","WEHI_539",0.778,{"v":4.72e-06,"d":"4.72E-06"},-0.584,0.0175,-4.88,{"v":1.04E-6,"d":"1.04E-06"},{"v":4.98e-06,"d":"4.98E-06"},0.111,"+/-","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["CDC25C","Cytarabine",0.641,0.00056,-0.773,0.000441,-5.11,{"v":3.2e-07,"d":"3.20E-07"},{"v":3.74e-06,"d":"3.74E-06"},0.112,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["MCM10","Cytarabine",0.726,{"v":4.06e-05,"d":"4.06E-05"},-0.657,0.00572,-4.88,{"v":1.07e-06,"d":"1.07E-06"},{"v":5.48E-6,"d":"5.48E-06"},0.115,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["AP3S1","Gemcitabine",-0.664,0.000298,0.755,0.000725,5.1,{"v":3.42e-07,"d":"3.42E-07"},{"v":4.73e-06,"d":"4.73E-06"},0.116,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["ABI3","Cladribine",-0.681,0.000177,0.739,1.08E-3,5.09,{"v":3.64e-07,"d":"3.64E-07"},{"v":4.73e-06,"d":"4.73E-06"},0.116,"-/+","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["ABI3","Cytarabine",-0.751,{"v":1.51e-05,"d":"1.51E-05"},0.657,0.00571,5.04,{"v":4.68e-07,"d":"4.68E-07"},{"v":5.48E-6,"d":"5.48E-06"},0.116,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ARHGAP1","8_amino_adenosine",-0.48,0.0151,0.841,{"v":4.42e-05,"d":"4.42E-05"},5,{"v":5.74e-07,"d":"5.74E-07"},{"v":6.48e-06,"d":"6.48E-06"},0.116,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["AGO1","Cytarabine",-0.631,0.000717,0.763,0.000584,4.99,{"v":5.92e-07,"d":"5.92E-07"},{"v":6.73e-06,"d":"6.73E-06"},0.116,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["CAMKMT","A_1155463",-0.572,2.8E-3,0.798,0.000211,4.99,{"v":6.18e-07,"d":"6.18E-07"},{"v":6.98e-06,"d":"6.98E-06"},0.116,"-/+","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2","Apoptotic modulator"]
["CASP10","Tozasertib",-0.682,0.000172,0.721,1.64E-3,4.98,{"v":6.37E-7,"d":"6.37E-07"},{"v":7.23e-06,"d":"7.23E-06"},0.116,"-/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["ARHGAP23","Amsacrine",0.487,0.0136,-0.836,{"v":5.45e-05,"d":"5.45E-05"},-4.97,{"v":6.56e-07,"d":"6.56E-07"},{"v":7.23e-06,"d":"7.23E-06"},0.116,"+/-","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["AP3S1","Topotecan",-0.591,0.00185,0.785,0.000317,4.97,{"v":6.8e-07,"d":"6.80E-07"},{"v":7.23e-06,"d":"7.23E-06"},0.116,"-/+","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["CASP10","Danusertib",-0.637,0.000616,0.754,0.000744,4.96,{"v":7.07e-07,"d":"7.07E-07"},{"v":7.73e-06,"d":"7.73E-06"},0.116,"-/+","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["ARIH2","Perifosine",0.122,0.561,-0.923,{"v":3.46E-7,"d":"3.46E-07"},-4.95,{"v":7.32e-07,"d":"7.32E-07"},{"v":7.97e-06,"d":"7.97E-06"},0.116,"0/-","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["CBX6","Cisplatin",-0.435,0.0298,0.853,{"v":2.72E-5,"d":"2.72E-05"},4.95,{"v":7.41e-07,"d":"7.41E-07"},{"v":7.97e-06,"d":"7.97E-06"},0.116,"-/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["C21orf91","BI_2536",0.685,0.000157,-0.713,0.00195,-4.95,{"v":7.46e-07,"d":"7.46E-07"},{"v":7.97e-06,"d":"7.97E-06"},0.116,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["BUB1","Cytarabine",0.783,{"v":3.78e-06,"d":"3.78E-06"},-0.586,0.0171,-4.93,{"v":8.38e-07,"d":"8.38E-07"},{"v":8.22e-06,"d":"8.22E-06"},0.116,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ARHGAP32","KU_60019",0.493,0.0123,-0.827,{"v":7.75E-5,"d":"7.75E-05"},-4.91,{"v":8.95e-07,"d":"8.95E-07"},{"v":8.47e-06,"d":"8.47E-06"},0.116,"+/-","ATM inhibitor","ATM","Kinase inhibitor"]
["CCDC117","BMS_754807",0.371,0.0678,-0.866,{"v":1.45E-5,"d":"1.45E-05"},-4.88,{"v":1.07e-06,"d":"1.07E-06"},{"v":8.97e-06,"d":"8.97E-06"},0.116,"0/-","IGF1R inhibitor","IGF1R","Kinase inhibitor"]
["ABCD1","Pomalidomide",0.666,0.000279,-0.717,0.00176,-4.88,{"v":1.08E-6,"d":"1.08E-06"},{"v":8.97e-06,"d":"8.97E-06"},0.116,"+/-","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["ATP5F1A","Litronesib",-0.25,0.228,0.895,{"v":2.84e-06,"d":"2.84E-06"},4.87,{"v":1.14e-06,"d":"1.14E-06"},{"v":9.47e-06,"d":"9.47E-06"},0.116,"0/+","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["BUB1","Cytarabine.Idarubicin",0.764,{"v":8.95e-06,"d":"8.95E-06"},-0.602,0.0137,-4.86,{"v":1.17E-6,"d":"1.17E-06"},{"v":9.47e-06,"d":"9.47E-06"},0.116,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["CASP10","VER_155008",-0.686,1.56E-4,0.694,0.00287,4.84,{"v":1.27e-06,"d":"1.27E-06"},{"v":9.47e-06,"d":"9.47E-06"},0.116,"-/+","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["CHORDC1","Pemetrexed",0.819,{"v":5.45e-07,"d":"5.45E-07"},-0.547,0.0283,-5.06,{"v":4.24e-07,"d":"4.24E-07"},{"v":4.98e-06,"d":"4.98E-06"},0.128,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["CDC7","Cytarabine.Idarubicin",0.642,0.000547,-0.764,0.000569,-5.05,{"v":4.4e-07,"d":"4.40E-07"},{"v":4.98e-06,"d":"4.98E-06"},0.128,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["EEF1D","Cytarabine",0.625,0.00083,-0.769,{"v":0.0005,"d":"5.00E-04"},-5.01,{"v":5.56e-07,"d":"5.56E-07"},{"v":5.98e-06,"d":"5.98E-06"},0.128,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["DNA2","SN_38",0.523,0.00736,-0.821,{"v":9.6e-05,"d":"9.60E-05"},-4.98,{"v":6.51e-07,"d":"6.51E-07"},{"v":6.73e-06,"d":"6.73E-06"},0.128,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["CSTF2","Mitomycin_C",-0.212,0.309,-0.961,{"v":3.47e-09,"d":"3.47E-09"},-4.98,{"v":6.52e-07,"d":"6.52E-07"},{"v":6.73e-06,"d":"6.73E-06"},0.128,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["CSTF2","Losmapimod",-0.131,0.533,-0.954,{"v":1.1e-08,"d":"1.10E-08"},-4.97,{"v":6.75E-7,"d":"6.75E-07"},{"v":6.73e-06,"d":"6.73E-06"},0.128,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["CHORDC1","Raltitrexed",0.826,{"v":3.59e-07,"d":"3.59E-07"},-0.503,0.0472,-4.94,{"v":7.64e-07,"d":"7.64E-07"},{"v":7.23e-06,"d":"7.23E-06"},0.128,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["CHORDC1","Gemcitabine",0.713,{"v":6.43e-05,"d":"6.43E-05"},-0.683,0.00353,-4.94,{"v":7.87e-07,"d":"7.87E-07"},{"v":7.23e-06,"d":"7.23E-06"},0.128,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["EAPP","ODM_201",0.169,0.42,-0.915,{"v":7.06E-7,"d":"7.06E-07"},-4.93,{"v":8.14e-07,"d":"8.14E-07"},{"v":7.48e-06,"d":"7.48E-06"},0.128,"0/-","AR antagonist","AR","Hormone therapy"]
["ARIH2","Mitomycin_C",0.0964,0.647,-0.92,{"v":4.61e-07,"d":"4.61E-07"},-4.82,{"v":1.47e-06,"d":"1.47E-06"},{"v":1.12e-05,"d":"1.12E-05"},0.129,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["AGO1","SN_38",-0.563,0.00337,0.776,4.08E-4,4.78,{"v":1.73E-6,"d":"1.73E-06"},{"v":1.17E-5,"d":"1.17E-05"},0.129,"-/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["BTD","VER_155008",-0.241,0.245,0.891,{"v":3.74e-06,"d":"3.74E-06"},4.78,{"v":1.78e-06,"d":"1.78E-06"},{"v":1.22E-5,"d":"1.22E-05"},0.129,"0/+","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["ATP5F1B","Litronesib",-0.229,0.27,0.893,{"v":3.23E-6,"d":"3.23E-06"},4.77,{"v":1.8e-06,"d":"1.80E-06"},{"v":1.25e-05,"d":"1.25E-05"},0.129,"0/+","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["ABI3","Gemcitabine",-0.638,0.000594,0.72,1.66E-3,4.75,{"v":1.99E-6,"d":"1.99E-06"},{"v":1.37e-05,"d":"1.37E-05"},0.129,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["ADGRE5","8_amino_adenosine",-0.513,0.00875,0.798,0.000211,4.75,{"v":2.08E-6,"d":"2.08E-06"},{"v":1.42E-5,"d":"1.42E-05"},0.129,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["APAF1","Cytarabine",-0.797,{"v":1.84E-6,"d":"1.84E-06"},0.511,0.0433,4.73,{"v":2.26E-6,"d":"2.26E-06"},{"v":1.45E-5,"d":"1.45E-05"},0.129,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["CAPRIN1","Raltitrexed",0.845,{"v":1.09E-7,"d":"1.09E-07"},-0.393,0.132,-4.73,{"v":2.29e-06,"d":"2.29E-06"},{"v":1.47E-5,"d":"1.47E-05"},0.129,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["ABI3","Cytarabine.Idarubicin",-0.741,{"v":2.24e-05,"d":"2.24E-05"},0.604,0.0133,4.72,{"v":2.32e-06,"d":"2.32E-06"},{"v":1.5E-5,"d":"1.50E-05"},0.129,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["ARIH2","Imiquimod",-0.283,0.171,-0.96,{"v":4.18E-9,"d":"4.18E-09"},-4.72,{"v":2.36e-06,"d":"2.36E-06"},{"v":1.5E-5,"d":"1.50E-05"},0.129,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["AK6","Pemetrexed",0.601,1.47E-3,-0.742,1E-3,-4.72,{"v":2.4e-06,"d":"2.40E-06"},{"v":1.5E-5,"d":"1.50E-05"},0.129,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["ABHD12","IOX_1",-0.666,0.000276,0.685,0.00344,4.69,{"v":2.69e-06,"d":"2.69E-06"},{"v":1.59E-5,"d":"1.59E-05"},0.129,"-/+","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["AP3S1","Fludarabine",-0.552,0.00419,0.768,0.000509,4.68,{"v":2.84e-06,"d":"2.84E-06"},{"v":1.67e-05,"d":"1.67E-05"},0.129,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["CBL","Crenolanib",-0.437,0.0287,0.824,{"v":8.84e-05,"d":"8.84E-05"},4.68,{"v":2.88E-6,"d":"2.88E-06"},{"v":1.67e-05,"d":"1.67E-05"},0.129,"-/+","PDGFRA and PDGFRB inhibitor","PDGFRA","Kinase inhibitor"]
["ADA2","Raltitrexed",-0.351,0.0856,0.854,{"v":2.59e-05,"d":"2.59E-05"},4.68,{"v":2.92E-6,"d":"2.92E-06"},{"v":1.69e-05,"d":"1.69E-05"},0.129,"0/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["AGO1","Clofarabine",-0.549,0.0045,0.769,0.000505,4.67,{"v":3.02e-06,"d":"3.02E-06"},{"v":1.72e-05,"d":"1.72E-05"},0.129,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["AFAP1L2","Glasdegib",0.599,1.57E-3,-0.736,1.15E-3,-4.67,{"v":3.05E-6,"d":"3.05E-06"},{"v":1.72e-05,"d":"1.72E-05"},0.129,"+/-","Smo inhibitor","SMO","Hedgehog inhibitor"]
["BRPF1","Docetaxel",-0.353,0.0834,0.852,{"v":2.79e-05,"d":"2.79E-05"},4.67,{"v":3.06e-06,"d":"3.06E-06"},{"v":1.72e-05,"d":"1.72E-05"},0.129,"0/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["RNF213","Gemcitabine",-0.447,0.0252,0.853,{"v":2.72E-5,"d":"2.72E-05"},4.99,{"v":6.01e-07,"d":"6.01E-07"},{"v":3.99e-06,"d":"3.99E-06"},0.129,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["ATP5PO","Filanesib",-0.425,0.0342,0.826,{"v":8.17e-05,"d":"8.17E-05"},4.65,{"v":3.25e-06,"d":"3.25E-06"},{"v":1.79e-05,"d":"1.79E-05"},0.13,"-/+","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["AP3S1","Clofarabine",-0.561,0.00351,0.758,0.000661,4.65,{"v":3.29e-06,"d":"3.29E-06"},{"v":1.87e-05,"d":"1.87E-05"},0.13,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["ABI3","Clofarabine",-0.721,{"v":4.77e-05,"d":"4.77E-05"},0.614,0.0113,4.65,{"v":3.36E-6,"d":"3.36E-06"},{"v":1.89e-05,"d":"1.89E-05"},0.13,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["BUB1","Etoposide",0.747,{"v":1.81e-05,"d":"1.81E-05"},-0.578,0.019,-4.64,{"v":3.41E-6,"d":"3.41E-06"},{"v":1.92e-05,"d":"1.92E-05"},0.13,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["ATP13A1","Pomalidomide",0.202,0.334,-0.889,{"v":4.03e-06,"d":"4.03E-06"},-4.64,{"v":3.47e-06,"d":"3.47E-06"},{"v":1.92e-05,"d":"1.92E-05"},0.13,"0/-","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["CHORDC1","Cytarabine",0.746,{"v":1.85e-05,"d":"1.85E-05"},-0.641,0.0075,-4.93,{"v":8.37e-07,"d":"8.37E-07"},{"v":7.97e-06,"d":"7.97E-06"},0.13,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ABRAXAS1","Foretinib",0.247,0.235,-0.878,{"v":7.79E-6,"d":"7.79E-06"},-4.63,{"v":3.71e-06,"d":"3.71E-06"},{"v":1.99e-05,"d":"1.99E-05"},0.132,"0/-","MET, VEGFR2 inhibitor","MET;KDR","Kinase inhibitor"]
["MAPK8","Fulvestrant",-0.584,2.16E-3,0.773,0.000442,4.85,{"v":1.22E-6,"d":"1.22E-06"},{"v":6.73e-06,"d":"6.73E-06"},0.133,"-/+","Estrogen receptor antagonist","ESR1","Hormone therapy"]
["RELL1","SN_38",-0.49,0.0129,0.829,{"v":7.11e-05,"d":"7.11E-05"},4.92,{"v":8.5e-07,"d":"8.50E-07"},{"v":4.49e-06,"d":"4.49E-06"},0.133,"-/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["SASS6","Prexasertib",0.849,{"v":8.22e-08,"d":"8.22E-08"},-0.434,0.0932,-4.91,{"v":9.26e-07,"d":"9.26E-07"},{"v":5.23e-06,"d":"5.23E-06"},0.133,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["RELB","Imiquimod",-0.105,0.617,0.923,{"v":3.45e-07,"d":"3.45E-07"},4.9,{"v":9.36e-07,"d":"9.36E-07"},{"v":5.23e-06,"d":"5.23E-06"},0.133,"0/+","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["TNS3","AZD3965",-0.051,0.809,0.945,{"v":3.45e-08,"d":"3.45E-08"},5.25,{"v":1.55E-7,"d":"1.55E-07"},{"v":2.74E-6,"d":"2.74E-06"},0.134,"0/+","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["THAP7","Perifosine",-0.572,2.82E-3,0.826,{"v":8.13e-05,"d":"8.13E-05"},5.22,{"v":1.82e-07,"d":"1.82E-07"},{"v":2.99e-06,"d":"2.99E-06"},0.134,"-/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["TIAM1","AT_406",-0.413,0.0403,0.879,{"v":7.48e-06,"d":"7.48E-06"},5.17,{"v":2.33e-07,"d":"2.33E-07"},{"v":3.24e-06,"d":"3.24E-06"},0.134,"-/+","XIAP, cIAP1, cIAP2 inhibitor","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["SPAG5","Cladribine",0.654,0.000395,-0.768,0.000512,-5.14,{"v":2.79E-7,"d":"2.79E-07"},{"v":3.49E-6,"d":"3.49E-06"},0.134,"+/-","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["CDC45","Raltitrexed",0.617,1.01E-3,-0.757,0.00069,-4.89,{"v":1.03e-06,"d":"1.03E-06"},{"v":9.22e-06,"d":"9.22E-06"},0.136,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["EEF1D","Cytarabine.Idarubicin",0.643,0.000526,-0.737,0.00113,-4.88,{"v":1.07e-06,"d":"1.07E-06"},{"v":9.47e-06,"d":"9.47E-06"},0.136,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["CSTF2","Perifosine",-0.216,0.3,-0.958,{"v":5.17e-09,"d":"5.17E-09"},-4.88,{"v":1.07e-06,"d":"1.07E-06"},{"v":9.47e-06,"d":"9.47E-06"},0.136,"0/-","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["C11orf98","GSK_461364",0.541,0.00521,-0.764,0.000568,-4.61,{"v":4.07E-6,"d":"4.07E-06"},{"v":2.12E-5,"d":"2.12E-05"},0.137,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["AGO1","Topotecan",-0.454,0.0225,0.807,0.000158,4.6,{"v":4.27e-06,"d":"4.27E-06"},{"v":2.24e-05,"d":"2.24E-05"},0.137,"-/+","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["BOP1","BMS863233",0.231,0.266,-0.879,{"v":7.35e-06,"d":"7.35E-06"},-4.59,{"v":4.36e-06,"d":"4.36E-06"},{"v":2.29e-05,"d":"2.29E-05"},0.137,"0/-","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["CBX6","Cytarabine.Idarubicin",-0.571,0.00286,0.742,0.000992,4.59,{"v":4.49e-06,"d":"4.49E-06"},{"v":2.39e-05,"d":"2.39E-05"},0.137,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["C1orf112","Dactinomycin",0.588,2E-3,-0.731,0.0013,-4.59,{"v":4.5e-06,"d":"4.50E-06"},{"v":2.39e-05,"d":"2.39E-05"},0.137,"+/-","RNA and DNA synthesis inhibitor","DNA","Conv.Chemo"]
["ABCD1","GSK_461364",-0.376,0.0641,0.835,{"v":5.81e-05,"d":"5.81E-05"},4.57,{"v":4.92e-06,"d":"4.92E-06"},{"v":2.54e-05,"d":"2.54E-05"},0.137,"0/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["CASP10","TAK_901",-0.587,0.00203,0.728,1.39E-3,4.57,{"v":4.96e-06,"d":"4.96E-06"},{"v":2.54e-05,"d":"2.54E-05"},0.137,"-/+","Aurora, Src family, JAK3, RTK inhibitor","AURKA;AURKB;JAK3;SRC;CLK2;FGR;LRRK2;YES1;LCK;FYN;ABL1;AXL;ABL2;HCK;RET;FRK;NTRK1;FGFR2","Kinase inhibitor"]
["CARNMT1","Cabozantinib",0.381,0.0606,-0.832,{"v":6.53e-05,"d":"6.53E-05"},-4.56,{"v":5.21e-06,"d":"5.21E-06"},{"v":2.77e-05,"d":"2.77E-05"},0.137,"0/-","VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor","KDR;MET;FLT3;KIT;RET;TEK","Kinase inhibitor"]
["ANKRD44","PF_670462",-0.457,0.0217,0.8,0.000198,4.55,{"v":5.32e-06,"d":"5.32E-06"},{"v":2.77e-05,"d":"2.77E-05"},0.137,"-/+","CK1epsilon and CK1delta inhibitor","CSNK1D;CSNK1E","Kinase inhibitor"]
["C1orf112","Cisplatin",0.573,0.00277,-0.734,0.00119,-4.55,{"v":5.49E-6,"d":"5.49E-06"},{"v":2.82e-05,"d":"2.82E-05"},0.137,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["AGO1","Gemcitabine",-0.631,0.00072,0.689,0.00319,4.54,{"v":5.63e-06,"d":"5.63E-06"},{"v":2.89e-05,"d":"2.89E-05"},0.137,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["ACYP2","Prexasertib",-0.755,{"v":1.27E-5,"d":"1.27E-05"},0.537,0.032,4.53,{"v":5.88e-06,"d":"5.88E-06"},{"v":2.94E-5,"d":"2.94E-05"},0.137,"-/+","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ACBD3","Ganetespib",0.519,0.00789,-0.763,0.000585,-4.51,{"v":6.45e-06,"d":"6.45E-06"},{"v":3.04E-5,"d":"3.04E-05"},0.137,"+/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["ATP13A1","Paclitaxel",-0.318,0.122,0.848,{"v":3.39e-05,"d":"3.39E-05"},4.51,{"v":6.6e-06,"d":"6.60E-06"},{"v":3.04E-5,"d":"3.04E-05"},0.137,"0/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["AURKB","Cytarabine",0.762,{"v":9.68e-06,"d":"9.68E-06"},-0.517,0.0401,-4.5,{"v":6.88e-06,"d":"6.88E-06"},{"v":3.12e-05,"d":"3.12E-05"},0.137,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ATP13A1","Brigatinib",0.167,0.425,-0.886,{"v":4.86e-06,"d":"4.86E-06"},-4.5,{"v":6.91e-06,"d":"6.91E-06"},{"v":3.14e-05,"d":"3.14E-05"},0.137,"0/-","ALK inhibitor, including gatekeeper mutant ALK","ALK;ROS1;IGF1R;EGFR;INSR;ABL1;FLT3;MET;ERBB2;ERBB4","Kinase inhibitor"]
["C10orf88","Eltanexor",0.552,0.00422,-0.74,0.00105,-4.49,{"v":7.06e-06,"d":"7.06E-06"},{"v":3.16e-05,"d":"3.16E-05"},0.137,"+/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["CC2D1B","Cytarabine",-0.555,0.00401,0.737,0.00112,4.49,{"v":7.25E-6,"d":"7.25E-06"},{"v":3.16e-05,"d":"3.16E-05"},0.137,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["CBX6","Cytarabine",-0.624,0.000856,0.684,3.47E-3,4.48,{"v":7.34E-6,"d":"7.34E-06"},{"v":3.19e-05,"d":"3.19E-05"},0.137,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["C10orf88","Mitoxantrone",0.514,0.00859,-0.762,0.000606,-4.48,{"v":7.35e-06,"d":"7.35E-06"},{"v":3.19e-05,"d":"3.19E-05"},0.137,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["BABAM2","Foretinib",0.421,0.0362,-0.807,0.000157,-4.48,{"v":7.43E-6,"d":"7.43E-06"},{"v":3.24e-05,"d":"3.24E-05"},0.137,"+/-","MET, VEGFR2 inhibitor","MET;KDR","Kinase inhibitor"]
["AHSA1","Tipifarnib",0.239,0.251,-0.867,{"v":1.35e-05,"d":"1.35E-05"},-4.48,{"v":7.61E-6,"d":"7.61E-06"},{"v":3.34e-05,"d":"3.34E-05"},0.137,"0/-","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["BABAM2","Sitravatinib",0.547,0.00466,-0.739,1.06E-3,-4.47,{"v":7.86e-06,"d":"7.86E-06"},{"v":3.39e-05,"d":"3.39E-05"},0.137,"+/-","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["APAF1","Prexasertib",-0.723,{"v":4.39e-05,"d":"4.39E-05"},0.57,0.0212,4.47,{"v":7.98e-06,"d":"7.98E-06"},{"v":3.39e-05,"d":"3.39E-05"},0.137,"-/+","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["BRPF1","Paclitaxel",-0.338,0.0981,0.836,{"v":5.39e-05,"d":"5.39E-05"},4.46,{"v":8.08e-06,"d":"8.08E-06"},{"v":3.41e-05,"d":"3.41E-05"},0.137,"0/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["ADAM10","Mercaptopurine",-0.29,0.16,0.852,{"v":2.84e-05,"d":"2.84E-05"},4.46,{"v":8.15e-06,"d":"8.15E-06"},{"v":3.41e-05,"d":"3.41E-05"},0.137,"0/+","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["AP3S1","Cladribine",-0.584,0.00218,0.712,0.00196,4.46,{"v":8.2e-06,"d":"8.20E-06"},{"v":3.44e-05,"d":"3.44E-05"},0.137,"-/+","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["ATP13A1","Docetaxel",-0.341,0.0956,0.835,{"v":5.68e-05,"d":"5.68E-05"},4.46,{"v":8.26e-06,"d":"8.26E-06"},{"v":3.44e-05,"d":"3.44E-05"},0.137,"0/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["CAPRIN1","Pemetrexed",0.816,{"v":6.48e-07,"d":"6.48E-07"},-0.392,0.134,-4.46,{"v":8.26e-06,"d":"8.26E-06"},{"v":3.44e-05,"d":"3.44E-05"},0.137,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["ADA2","Cytarabine",-0.432,0.0311,0.8,2.02E-4,4.46,{"v":8.27e-06,"d":"8.27E-06"},{"v":3.44e-05,"d":"3.44E-05"},0.137,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["APOE","Daporinad",-0.636,0.000626,0.666,0.00483,4.45,{"v":8.65e-06,"d":"8.65E-06"},{"v":3.46e-05,"d":"3.46E-05"},0.137,"-/+","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["ARHGEF2","Pomalidomide",0.233,0.262,-0.866,{"v":1.42E-5,"d":"1.42E-05"},-4.45,{"v":8.67E-6,"d":"8.67E-06"},{"v":3.46e-05,"d":"3.46E-05"},0.137,"0/-","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["BAZ1A","8_amino_adenosine",0.628,0.000769,-0.672,0.00435,-4.44,{"v":9.01e-06,"d":"9.01E-06"},{"v":3.49e-05,"d":"3.49E-05"},0.137,"+/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["AP3S1","Cytarabine",-0.522,0.00747,0.749,0.000836,4.43,{"v":9.39e-06,"d":"9.39E-06"},{"v":3.49e-05,"d":"3.49E-05"},0.137,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["BRPF1","Cabazitaxel",-0.379,0.0621,0.818,1.07E-4,4.43,{"v":9.4e-06,"d":"9.40E-06"},{"v":3.49e-05,"d":"3.49E-05"},0.137,"0/+","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["CASP10","Axitinib",-0.63,0.000744,0.667,0.00473,4.42,{"v":9.78e-06,"d":"9.78E-06"},{"v":3.61e-05,"d":"3.61E-05"},0.138,"-/+","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["ADA2","Pemetrexed",-0.331,0.106,0.834,{"v":5.88e-05,"d":"5.88E-05"},4.42,{"v":9.88e-06,"d":"9.88E-06"},{"v":3.64e-05,"d":"3.64E-05"},0.138,"0/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["ARIH2","Enzalutamide",0.19,0.362,-0.874,{"v":9.85e-06,"d":"9.85E-06"},-4.4,{"v":1.06E-5,"d":"1.06E-05"},{"v":3.71e-05,"d":"3.71E-05"},0.138,"0/-","AR antagonist","AR","Hormone therapy"]
["AGPAT2","Temsirolimus",-0.344,0.0922,0.828,{"v":7.48e-05,"d":"7.48E-05"},4.4,{"v":1.07e-05,"d":"1.07E-05"},{"v":3.74e-05,"d":"3.74E-05"},0.138,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ATP5PO","Litronesib",-0.316,0.124,0.836,{"v":5.43e-05,"d":"5.43E-05"},4.39,{"v":1.14e-05,"d":"1.14E-05"},{"v":3.86e-05,"d":"3.86E-05"},0.14,"0/+","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["BTG3","BX_912",0.548,0.00453,-0.724,0.00153,-4.38,{"v":1.2E-5,"d":"1.20E-05"},{"v":3.94e-05,"d":"3.94E-05"},0.14,"+/-","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["AK6","Prexasertib",0.65,4.35E-4,-0.637,0.00802,-4.37,{"v":1.26E-5,"d":"1.26E-05"},{"v":4.04e-05,"d":"4.04E-05"},0.14,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["CASP10","Midostaurin",-0.673,0.000228,0.61,0.0122,4.36,{"v":1.32e-05,"d":"1.32E-05"},{"v":4.11e-05,"d":"4.11E-05"},0.14,"-/+","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["ADGRE5","Tozasertib",-0.518,0.008,0.74,0.00105,4.35,{"v":1.33E-5,"d":"1.33E-05"},{"v":4.14e-05,"d":"4.14E-05"},0.14,"-/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["ARIH2","IOX_2",0.164,0.434,-0.876,{"v":8.71e-06,"d":"8.71E-06"},-4.35,{"v":1.34E-5,"d":"1.34E-05"},{"v":4.14e-05,"d":"4.14E-05"},0.14,"0/-","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["CBX6","Gemcitabine",-0.544,0.00493,0.721,0.00161,4.35,{"v":1.39e-05,"d":"1.39E-05"},{"v":4.14e-05,"d":"4.14E-05"},0.14,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["ATF2","AZD7762",-0.688,1.46E-4,0.589,0.0164,4.34,{"v":1.4E-5,"d":"1.40E-05"},{"v":4.14e-05,"d":"4.14E-05"},0.14,"-/+","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["CARNMT1","Glesatinib",0.57,0.00294,-0.702,0.00245,-4.34,{"v":1.43E-5,"d":"1.43E-05"},{"v":4.19e-05,"d":"4.19E-05"},0.14,"+/-","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["ZBTB10","Ibrutinib",0.606,1.33E-3,-0.739,1.07E-3,-4.72,{"v":2.38e-06,"d":"2.38E-06"},{"v":7.99e-06,"d":"7.99E-06"},0.14,"+/-","BTK inhibitor","BTK;BLK;EGFR;FYN;LYN;LCK;BRAF;WNK1","Kinase inhibitor"]
["UTP20","Quizartinib",0.535,0.00581,-0.781,0.000354,-4.71,{"v":2.54e-06,"d":"2.54E-06"},{"v":8.24e-06,"d":"8.24E-06"},0.14,"+/-","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["ZNF823","AR_42",-0.537,0.00565,0.777,0.000399,4.68,{"v":2.86e-06,"d":"2.86E-06"},{"v":9.24e-06,"d":"9.24E-06"},0.14,"-/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["USP10","Prexasertib",0.789,{"v":2.77e-06,"d":"2.77E-06"},-0.509,0.0439,-4.66,{"v":3.13e-06,"d":"3.13E-06"},{"v":9.99e-06,"d":"9.99E-06"},0.14,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ZNF77","Losmapimod",-0.0649,0.758,-0.935,{"v":1.13e-07,"d":"1.13E-07"},-4.66,{"v":3.16e-06,"d":"3.16E-06"},{"v":9.99e-06,"d":"9.99E-06"},0.14,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["ZBTB4","AT13148",-0.198,0.342,0.891,{"v":3.71e-06,"d":"3.71E-06"},4.65,{"v":3.32E-6,"d":"3.32E-06"},{"v":1.07e-05,"d":"1.07E-05"},0.14,"0/+","p70S6K, PKA, ROCK (AKT) inhibitor","AKT1;AKT2;AKT3;RPS6KB1;ROCK1;ROCK2;PRKACA;PRKACB;PRKACG","Kinase inhibitor"]
["VHL","Vincristine",0.676,0.000208,-0.666,0.00489,-4.64,{"v":3.42e-06,"d":"3.42E-06"},{"v":1.15E-5,"d":"1.15E-05"},0.14,"+/-","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB;TUBA4A","Conv.Chemo"]
["ZNF77","Mitomycin_C",-0.174,0.407,-0.947,{"v":2.91e-08,"d":"2.91E-08"},-4.64,{"v":3.54E-6,"d":"3.54E-06"},{"v":1.15E-5,"d":"1.15E-05"},0.14,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["UBASH3A","Valrubicin",-0.431,0.0314,0.821,{"v":9.65e-05,"d":"9.65E-05"},4.64,{"v":3.56e-06,"d":"3.56E-06"},{"v":1.15E-5,"d":"1.15E-05"},0.14,"-/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["ZNF518B","UNC0638",0.534,0.00592,-0.772,0.000459,-4.64,{"v":3.57e-06,"d":"3.57E-06"},{"v":1.15E-5,"d":"1.15E-05"},0.14,"+/-","G9a, GLP inhibitor","EHMT2","Differentiating.epigenetic modifier"]
["WDR37","Prexasertib",-0.771,{"v":6.56e-06,"d":"6.56E-06"},0.536,0.0325,4.63,{"v":3.64e-06,"d":"3.64E-06"},{"v":1.2E-5,"d":"1.20E-05"},0.14,"-/+","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["TRIM23","Tasquinimod",-0.762,{"v":9.63e-06,"d":"9.63E-06"},0.55,0.0274,4.63,{"v":3.7e-06,"d":"3.70E-06"},{"v":1.2E-5,"d":"1.20E-05"},0.14,"-/+","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["CAPRIN1","Prexasertib",0.86,{"v":3.55E-8,"d":"3.55E-08"},-0.219,0.415,-4.34,{"v":1.45E-5,"d":"1.45E-05"},{"v":4.26e-05,"d":"4.26E-05"},0.141,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["DDX5","Cytarabine",0.778,{"v":4.81e-06,"d":"4.81E-06"},-0.58,0.0185,-4.86,{"v":1.15E-6,"d":"1.15E-06"},{"v":1.02e-05,"d":"1.02E-05"},0.141,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["C10orf88","Epirubicin",0.638,0.000606,-0.641,7.45E-3,-4.33,{"v":1.5E-5,"d":"1.50E-05"},{"v":4.34e-05,"d":"4.34E-05"},0.142,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["FOXP1","IOX_2",0.278,0.178,-0.905,{"v":1.47e-06,"d":"1.47E-06"},-5.1,{"v":3.39E-7,"d":"3.39E-07"},{"v":4.73e-06,"d":"4.73E-06"},0.144,"0/-","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["GLYR1","Imiquimod",0.334,0.103,-0.892,{"v":3.39e-06,"d":"3.39E-06"},-5.09,{"v":3.63e-07,"d":"3.63E-07"},{"v":4.98e-06,"d":"4.98E-06"},0.144,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["GNG2","Tozasertib",-0.844,{"v":1.17E-7,"d":"1.17E-07"},0.478,0.0611,5.02,{"v":5.29e-07,"d":"5.29E-07"},{"v":5.73e-06,"d":"5.73E-06"},0.144,"-/0","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["FKTN","Sunitinib",0.47,0.0179,-0.846,{"v":3.63e-05,"d":"3.63E-05"},-5.01,{"v":5.55e-07,"d":"5.55E-07"},{"v":6.23e-06,"d":"6.23E-06"},0.144,"+/-","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["FKTN","Glesatinib",0.545,0.00485,-0.806,0.000161,-4.94,{"v":7.83e-07,"d":"7.83E-07"},{"v":7.73e-06,"d":"7.73E-06"},0.144,"+/-","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["FBXO7","ODM_201",-0.854,{"v":5.5e-08,"d":"5.50E-08"},0.412,0.113,4.89,{"v":1.02E-6,"d":"1.02E-06"},{"v":8.97e-06,"d":"8.97E-06"},0.144,"-/0","AR antagonist","AR","Hormone therapy"]
["EIF4G2","Raltitrexed",0.759,{"v":1.1E-5,"d":"1.10E-05"},-0.606,0.0129,-4.85,{"v":1.25e-06,"d":"1.25E-06"},{"v":9.47e-06,"d":"9.47E-06"},0.144,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["EIF3I","Pemetrexed",0.682,1.74E-4,-0.697,0.00272,-4.84,{"v":1.3E-6,"d":"1.30E-06"},{"v":9.72e-06,"d":"9.72E-06"},0.144,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["GMNN","Carboplatin",0.517,0.00812,-0.808,1.54E-4,-4.84,{"v":1.31E-6,"d":"1.31E-06"},{"v":9.72e-06,"d":"9.72E-06"},0.144,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["EIF3G","Pemetrexed",0.717,{"v":5.56e-05,"d":"5.56E-05"},-0.653,0.00615,-4.8,{"v":1.56e-06,"d":"1.56E-06"},{"v":9.97e-06,"d":"9.97E-06"},0.144,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["EIF3G","Raltitrexed",0.704,{"v":8.51e-05,"d":"8.51E-05"},-0.665,0.00492,-4.8,{"v":1.61E-6,"d":"1.61E-06"},{"v":1.02e-05,"d":"1.02E-05"},0.144,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["GMNN","Cisplatin",0.483,0.0145,-0.818,0.000109,-4.79,{"v":1.64E-6,"d":"1.64E-06"},{"v":1.02e-05,"d":"1.02E-05"},0.144,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["FGFR1OP","Cytarabine.Idarubicin",0.431,0.0313,-0.836,{"v":5.48e-05,"d":"5.48E-05"},-4.77,{"v":1.82e-06,"d":"1.82E-06"},{"v":1.12e-05,"d":"1.12E-05"},0.144,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["HOXB4","Romidepsin",0.438,0.0284,-0.833,{"v":6.1e-05,"d":"6.10E-05"},-4.77,{"v":1.83e-06,"d":"1.83E-06"},{"v":1.12e-05,"d":"1.12E-05"},0.144,"+/-","HDAC inhibitor","HDAC1;HDAC2","Differentiating.epigenetic modifier"]
["EIF4G2","Cytarabine.Idarubicin",0.74,{"v":2.37E-5,"d":"2.37E-05"},-0.616,0.0111,-4.77,{"v":1.84E-6,"d":"1.84E-06"},{"v":1.12e-05,"d":"1.12E-05"},0.144,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["FMR1","Imiquimod",0.11,0.601,-0.915,{"v":6.99E-7,"d":"6.99E-07"},-4.76,{"v":1.91e-06,"d":"1.91E-06"},{"v":1.15E-5,"d":"1.15E-05"},0.144,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["HMBS","SN_38",0.382,0.0594,-0.851,{"v":2.9E-5,"d":"2.90E-05"},-4.75,{"v":2e-06,"d":"2.00E-06"},{"v":1.22E-5,"d":"1.22E-05"},0.144,"0/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["EIF2AK4","Litronesib",-0.598,0.00159,0.747,0.000893,4.73,{"v":2.23e-06,"d":"2.23E-06"},{"v":1.27E-5,"d":"1.27E-05"},0.144,"-/+","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["EIF3I","Raltitrexed",0.629,0.000764,-0.723,0.00154,-4.73,{"v":2.27e-06,"d":"2.27E-06"},{"v":1.27E-5,"d":"1.27E-05"},0.144,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["HIRIP3","IOX_2",0.292,0.157,-0.875,{"v":9.3e-06,"d":"9.30E-06"},-4.73,{"v":2.3E-6,"d":"2.30E-06"},{"v":1.27E-5,"d":"1.27E-05"},0.144,"0/-","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["AGPAT2","Ridaforolimus",-0.277,0.181,0.842,{"v":4.26e-05,"d":"4.26E-05"},4.32,{"v":1.53e-05,"d":"1.53E-05"},{"v":4.51e-05,"d":"4.51E-05"},0.145,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["AGO1","Pemetrexed",-0.741,{"v":2.24e-05,"d":"2.24E-05"},0.507,0.0449,4.32,{"v":1.53e-05,"d":"1.53E-05"},{"v":4.54e-05,"d":"4.54E-05"},0.145,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["CASC3","8_amino_adenosine",0.42,0.0367,-0.787,{"v":0.0003,"d":"3.00E-04"},-4.32,{"v":1.58e-05,"d":"1.58E-05"},{"v":4.66e-05,"d":"4.66E-05"},0.145,"+/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["ABRAXAS1","Sitravatinib",0.353,0.0832,-0.815,1.21E-4,-4.32,{"v":1.59E-5,"d":"1.59E-05"},{"v":4.69e-05,"d":"4.69E-05"},0.145,"0/-","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["AP3D1","Cytarabine",-0.529,0.00652,0.726,0.00145,4.31,{"v":1.6e-05,"d":"1.60E-05"},{"v":4.71E-5,"d":"4.71E-05"},0.145,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["BRK1","Tasquinimod",-0.752,{"v":1.45E-5,"d":"1.45E-05"},0.486,0.0562,4.31,{"v":1.61e-05,"d":"1.61E-05"},{"v":4.73e-05,"d":"4.73E-05"},0.145,"-/0","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["ATG9A","Ridaforolimus",-0.344,0.0922,0.818,0.000109,4.31,{"v":1.62e-05,"d":"1.62E-05"},{"v":4.76e-05,"d":"4.76E-05"},0.145,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["CAPRIN1","Cytarabine",0.754,{"v":1.33E-5,"d":"1.33E-05"},-0.481,0.0591,-4.31,{"v":1.64e-05,"d":"1.64E-05"},{"v":4.76e-05,"d":"4.76E-05"},0.145,"+/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ABRAXAS1","Ponatinib",0.273,0.187,-0.842,{"v":4.34e-05,"d":"4.34E-05"},-4.31,{"v":1.65e-05,"d":"1.65E-05"},{"v":4.78e-05,"d":"4.78E-05"},0.145,"0/-","Broad TK inhibitor","ABL1;PDGFRA;KDR;FGFR1;SRC;KIT","Kinase inhibitor"]
["ATP5PD","Litronesib",-0.343,0.0934,0.817,1.12E-4,4.3,{"v":1.69e-05,"d":"1.69E-05"},{"v":4.86e-05,"d":"4.86E-05"},0.145,"0/+","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["FMR1","Losmapimod",-0.174,0.404,-0.949,{"v":1.97e-08,"d":"1.97E-08"},-4.72,{"v":2.39E-6,"d":"2.39E-06"},{"v":1.32e-05,"d":"1.32E-05"},0.145,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["TMEM192","Cabazitaxel",-0.508,0.00946,0.84,{"v":4.74E-5,"d":"4.74E-05"},5.09,{"v":3.59e-07,"d":"3.59E-07"},{"v":4.73e-06,"d":"4.73E-06"},0.146,"-/+","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["SLC8A1","Filanesib",0.606,1.32E-3,-0.787,0.000298,-5.05,{"v":4.45e-07,"d":"4.45E-07"},{"v":5.23e-06,"d":"5.23E-06"},0.146,"+/-","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["TNKS1BP1","Cabazitaxel",0.377,0.0634,-0.878,{"v":7.82e-06,"d":"7.82E-06"},-5.04,{"v":4.68e-07,"d":"4.68E-07"},{"v":5.48E-6,"d":"5.48E-06"},0.146,"0/-","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["TAF4B","Quisinostat",-0.272,0.189,0.902,{"v":1.82e-06,"d":"1.82E-06"},5.03,{"v":4.84e-07,"d":"4.84E-07"},{"v":5.48E-6,"d":"5.48E-06"},0.146,"0/+","HDAC inhibitor","HDAC1;HDAC2;HDAC4;HDAC10;HDAC11","Differentiating.epigenetic modifier"]
["ABCC10","Pevonedistat",-0.349,0.087,0.814,0.000124,4.3,{"v":1.72e-05,"d":"1.72E-05"},{"v":4.96e-05,"d":"4.96E-05"},0.147,"0/+","NAE inhibitor","NAE1","Metabolic modifier"]
["ARL8A","A_1331852",0.729,{"v":3.55e-05,"d":"3.55E-05"},-0.52,0.0392,-4.3,{"v":1.74e-05,"d":"1.74E-05"},{"v":5.01e-05,"d":"5.01E-05"},0.147,"+/-","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2;MCL1","Apoptotic modulator"]
["BCL9","PF_670462",0.518,0.00799,-0.73,1.34E-3,-4.29,{"v":1.77E-5,"d":"1.77E-05"},{"v":5.11e-05,"d":"5.11E-05"},0.149,"+/-","CK1epsilon and CK1delta inhibitor","CSNK1D;CSNK1E","Kinase inhibitor"]
["BUB1","Carboplatin",0.585,2.14E-3,-0.681,0.00368,-4.29,{"v":1.79e-05,"d":"1.79E-05"},{"v":5.16e-05,"d":"5.16E-05"},0.149,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["CDC7","Prexasertib",0.782,{"v":3.85e-06,"d":"3.85E-06"},-0.567,0.0221,-4.84,{"v":1.29e-06,"d":"1.29E-06"},{"v":1.15E-5,"d":"1.15E-05"},0.153,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["TSR1","Cladribine",0.483,0.0144,-0.793,0.00025,-4.59,{"v":4.43e-06,"d":"4.43E-06"},{"v":1.35e-05,"d":"1.35E-05"},0.153,"+/-","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["ATPAF1","C646",0.277,0.18,-0.838,{"v":5.09e-05,"d":"5.09E-05"},-4.28,{"v":1.85e-05,"d":"1.85E-05"},{"v":5.38E-5,"d":"5.38E-05"},0.154,"0/-","EP300, CREB-binding protein (CBP) inhibitor","EP300","Differentiating.epigenetic modifier"]
["BTD","8_amino_adenosine",-0.47,0.0177,0.756,0.000699,4.28,{"v":1.85e-05,"d":"1.85E-05"},{"v":5.41E-5,"d":"5.41E-05"},0.154,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["ACTR1A","RGFP966",0.588,0.00201,-0.677,0.00399,-4.28,{"v":1.88E-5,"d":"1.88E-05"},{"v":5.46e-05,"d":"5.46E-05"},0.154,"+/-","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["CASC3","RGFP966",0.588,1.99E-3,-0.676,0.00407,-4.28,{"v":1.91E-5,"d":"1.91E-05"},{"v":5.51e-05,"d":"5.51E-05"},0.154,"+/-","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["CDC25C","Clofarabine",0.561,0.0035,-0.784,0.000326,-4.83,{"v":1.35E-6,"d":"1.35E-06"},{"v":1.2E-5,"d":"1.20E-05"},0.154,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["JPT2","Mitomycin_C",0.538,0.00556,-0.796,0.000225,-4.83,{"v":1.38e-06,"d":"1.38E-06"},{"v":8.22e-06,"d":"8.22E-06"},0.154,"+/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["JADE3","Gemcitabine",0.373,0.0663,-0.857,{"v":2.18e-05,"d":"2.18E-05"},-4.79,{"v":1.67e-06,"d":"1.67E-06"},{"v":9.47e-06,"d":"9.47E-06"},0.154,"0/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["MICU2","Temsirolimus",-0.417,0.0379,0.841,{"v":4.43e-05,"d":"4.43E-05"},4.77,{"v":1.81E-6,"d":"1.81E-06"},{"v":9.97e-06,"d":"9.97E-06"},0.154,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["IDH3A","Merestinib",0.613,0.00113,-0.741,0.00102,-4.76,{"v":1.89e-06,"d":"1.89E-06"},{"v":1.02e-05,"d":"1.02E-05"},0.154,"+/-","MET inhibitor","MET","Kinase inhibitor"]
["KNSTRN","Cladribine",0.624,0.000849,-0.726,0.00146,-4.72,{"v":2.34E-6,"d":"2.34E-06"},{"v":1.2E-5,"d":"1.20E-05"},0.154,"+/-","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["KPNA2","Cytarabine",0.742,{"v":2.14e-05,"d":"2.14E-05"},-0.602,0.0137,-4.72,{"v":2.34E-6,"d":"2.34E-06"},{"v":1.25e-05,"d":"1.25E-05"},0.154,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["MCM10","Pemetrexed",0.657,3.59E-4,-0.698,2.64E-3,-4.72,{"v":2.36e-06,"d":"2.36E-06"},{"v":1.25e-05,"d":"1.25E-05"},0.154,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["LSM11","GSK_461364",0.542,0.00517,-0.78,0.00037,-4.72,{"v":2.38e-06,"d":"2.38E-06"},{"v":1.27E-5,"d":"1.27E-05"},0.154,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["JPT2","Vinblastine",0.533,6.13E-3,-0.782,0.00034,-4.7,{"v":2.56e-06,"d":"2.56E-06"},{"v":1.27E-5,"d":"1.27E-05"},0.154,"+/-","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["IDH3B","Sitravatinib",0.522,0.00739,-0.787,0.000294,-4.7,{"v":2.61E-6,"d":"2.61E-06"},{"v":1.27E-5,"d":"1.27E-05"},0.154,"+/-","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["MED26","BMS863233",0.364,0.0739,-0.852,{"v":2.85e-05,"d":"2.85E-05"},-4.7,{"v":2.65E-6,"d":"2.65E-06"},{"v":1.3e-05,"d":"1.30E-05"},0.154,"0/-","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["KIF4A","Pemetrexed",0.773,{"v":5.91e-06,"d":"5.91E-06"},-0.545,0.0289,-4.69,{"v":2.77e-06,"d":"2.77E-06"},{"v":1.32e-05,"d":"1.32E-05"},0.154,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["LCP2","Cytarabine.Idarubicin",-0.34,0.0959,0.856,{"v":2.3E-5,"d":"2.30E-05"},4.67,{"v":3e-06,"d":"3.00E-06"},{"v":1.35e-05,"d":"1.35E-05"},0.154,"0/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["ARID5B","PD0325901",0.294,0.154,-0.831,{"v":6.7e-05,"d":"6.70E-05"},-4.27,{"v":1.95E-5,"d":"1.95E-05"},{"v":5.68e-05,"d":"5.68E-05"},0.157,"0/-","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["CCDC167","Cytarabine.Idarubicin",0.858,{"v":4.2e-08,"d":"4.20E-08"},-0.204,0.448,-4.27,{"v":1.98E-5,"d":"1.98E-05"},{"v":5.73e-05,"d":"5.73E-05"},0.157,"+/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["ACAA2","Omacetaxine",-0.252,0.224,0.844,{"v":3.94e-05,"d":"3.94E-05"},4.27,{"v":1.98E-5,"d":"1.98E-05"},{"v":5.73e-05,"d":"5.73E-05"},0.157,"0/+","Protein synthesis inhib (80 S ribosome)","RPL3","Conv.Chemo"]
["ADAM9","Altiratinib",0.726,{"v":3.99e-05,"d":"3.99E-05"},-0.516,0.0408,-4.26,{"v":2.03e-05,"d":"2.03E-05"},{"v":5.83e-05,"d":"5.83E-05"},0.157,"+/-","MET, Tie-2 inhibitor","MET;NTRK1;NTRK3;NTRK2;TEK;FLT3;KIT;KDR","Kinase inhibitor"]
["ASB6","VER_155008",0.526,0.00697,-0.719,0.00168,-4.26,{"v":2.04e-05,"d":"2.04E-05"},{"v":5.83e-05,"d":"5.83E-05"},0.157,"+/-","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["FKBP15","MK_2206",-0.37,0.0687,0.848,{"v":3.35e-05,"d":"3.35E-05"},4.68,{"v":2.89e-06,"d":"2.89E-06"},{"v":1.47E-5,"d":"1.47E-05"},0.157,"0/+","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["ARHGAP17","Mitomycin_C",-0.22,0.29,0.853,{"v":2.72E-5,"d":"2.72E-05"},4.26,{"v":2.06e-05,"d":"2.06E-05"},{"v":5.93e-05,"d":"5.93E-05"},0.158,"0/+","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["ATP6V1G1","Vidofludimus",-0.404,0.045,0.785,0.000311,4.25,{"v":2.1e-05,"d":"2.10E-05"},{"v":5.98e-05,"d":"5.98E-05"},0.158,"-/+","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["KLHL26","IOX_2",0.318,0.121,-0.862,{"v":1.75e-05,"d":"1.75E-05"},-4.66,{"v":3.11e-06,"d":"3.11E-06"},{"v":1.42E-5,"d":"1.42E-05"},0.158,"0/-","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["BUB1","Amsacrine",0.652,0.000411,-0.609,0.0122,-4.25,{"v":2.13e-05,"d":"2.13E-05"},{"v":6.13e-05,"d":"6.13E-05"},0.159,"+/-","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["C16orf72","Rigosertib",0.72,{"v":4.9e-05,"d":"4.90E-05"},-0.521,0.0386,-4.25,{"v":2.17e-05,"d":"2.17E-05"},{"v":6.23e-05,"d":"6.23E-05"},0.159,"+/-","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["CASP1","Glasdegib",-0.359,0.0778,0.803,0.000182,4.24,{"v":2.26E-5,"d":"2.26E-05"},{"v":6.35e-05,"d":"6.35E-05"},0.159,"0/+","Smo inhibitor","SMO","Hedgehog inhibitor"]
["BABAM2","Lifirafenib_BGB_283",0.318,0.121,-0.818,1.06E-4,-4.24,{"v":2.28e-05,"d":"2.28E-05"},{"v":6.4e-05,"d":"6.40E-05"},0.159,"0/-","Raf inhibitor","RAF1;BRAF;EGFR","Kinase inhibitor"]
["APAF1","Raltitrexed",-0.651,0.000424,0.607,0.0127,4.23,{"v":2.29e-05,"d":"2.29E-05"},{"v":6.4e-05,"d":"6.40E-05"},0.159,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["BIRC6","Glasdegib",-0.895,{"v":1.65e-09,"d":"1.65E-09"},0.0368,0.892,4.23,{"v":2.3E-5,"d":"2.30E-05"},{"v":6.4e-05,"d":"6.40E-05"},0.159,"-/0","Smo inhibitor","SMO","Hedgehog inhibitor"]
["ARHGAP23","Etoposide",0.311,0.131,-0.82,{"v":9.94e-05,"d":"9.94E-05"},-4.23,{"v":2.36e-05,"d":"2.36E-05"},{"v":6.53e-05,"d":"6.53E-05"},0.159,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["ACBD3","Onalespib",0.325,0.113,-0.815,1.2E-4,-4.23,{"v":2.36e-05,"d":"2.36E-05"},{"v":6.53e-05,"d":"6.53E-05"},0.159,"0/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["AGO1","Prexasertib",-0.705,{"v":8.4e-05,"d":"8.40E-05"},0.539,0.0313,4.23,{"v":2.37E-5,"d":"2.37E-05"},{"v":6.53e-05,"d":"6.53E-05"},0.159,"-/+","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ANKRD46","Sunitinib",0.585,0.00212,-0.668,4.64E-3,-4.23,{"v":2.38e-05,"d":"2.38E-05"},{"v":6.58E-5,"d":"6.58E-05"},0.159,"+/-","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["AP3S1","Cytarabine.Idarubicin",-0.477,0.0158,0.743,0.000963,4.22,{"v":2.39e-05,"d":"2.39E-05"},{"v":6.58E-5,"d":"6.58E-05"},0.159,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["AP3D1","Gemcitabine",-0.558,0.00374,0.689,3.13E-3,4.22,{"v":2.42e-05,"d":"2.42E-05"},{"v":6.6e-05,"d":"6.60E-05"},0.159,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["BCAT2","GSK_461364",-0.523,7.26E-3,0.714,0.00188,4.22,{"v":2.43e-05,"d":"2.43E-05"},{"v":6.63e-05,"d":"6.63E-05"},0.159,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["BTD","IOX_1",-0.614,0.00111,0.641,0.00744,4.22,{"v":2.49e-05,"d":"2.49E-05"},{"v":6.68e-05,"d":"6.68E-05"},0.159,"-/+","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["ACAA2","RGFP966",-0.356,0.0812,0.802,0.000189,4.22,{"v":2.49e-05,"d":"2.49E-05"},{"v":6.8e-05,"d":"6.80E-05"},0.159,"0/+","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["ARL8A","A_1155463",0.723,{"v":4.51e-05,"d":"4.51E-05"},-0.508,0.0443,-4.21,{"v":2.52e-05,"d":"2.52E-05"},{"v":6.8e-05,"d":"6.80E-05"},0.159,"+/-","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2","Apoptotic modulator"]
["ASAH1","OSU_03012",-0.639,0.000589,0.615,0.0112,4.21,{"v":2.52e-05,"d":"2.52E-05"},{"v":6.88e-05,"d":"6.88E-05"},0.159,"-/+","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["ABRAXAS1","Glesatinib",0.232,0.264,-0.845,{"v":3.87e-05,"d":"3.87E-05"},-4.21,{"v":2.53e-05,"d":"2.53E-05"},{"v":6.88e-05,"d":"6.88E-05"},0.159,"0/-","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["AFG3L2","Belinostat",-0.422,0.0358,0.771,0.000472,4.21,{"v":2.56e-05,"d":"2.56E-05"},{"v":6.88e-05,"d":"6.88E-05"},0.159,"-/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["ACSL5","C646",-0.508,0.00959,0.722,1.58E-3,4.21,{"v":2.59e-05,"d":"2.59E-05"},{"v":6.98e-05,"d":"6.98E-05"},0.159,"-/+","EP300, CREB-binding protein (CBP) inhibitor","EP300","Differentiating.epigenetic modifier"]
["ARIH2","Exemestane",0.259,0.211,-0.835,{"v":5.72e-05,"d":"5.72E-05"},-4.2,{"v":2.67e-05,"d":"2.67E-05"},{"v":6.98e-05,"d":"6.98E-05"},0.159,"0/-","Aromatase inhibitor","CYP19A1","Hormone therapy"]
["UBASH3A","Etoposide",-0.375,0.0649,0.836,{"v":5.52E-5,"d":"5.52E-05"},4.58,{"v":4.71e-06,"d":"4.71E-06"},{"v":1.45E-5,"d":"1.45E-05"},0.159,"0/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["TBCC","Radotinib",-0.385,0.0571,0.867,{"v":1.36E-5,"d":"1.36E-05"},4.94,{"v":7.81e-07,"d":"7.81E-07"},{"v":6.73e-06,"d":"6.73E-06"},0.161,"0/+","ABL, PDGFR inhibitor","ABL1;PDGFRA;PDGFRB","Kinase inhibitor"]
["SH2D3C","Midostaurin",-0.525,0.007,0.815,1.21E-4,4.93,{"v":8.16E-7,"d":"8.16E-07"},{"v":6.98e-06,"d":"6.98E-06"},0.161,"-/+","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["TBCC","Imatinib",-0.551,0.00434,0.801,1.92E-4,4.92,{"v":8.72e-07,"d":"8.72E-07"},{"v":7.73e-06,"d":"7.73E-06"},0.162,"-/+","ABL, Kit, PDGFRB inhibitor","ABL1","Kinase inhibitor"]
["SPDL1","Prexasertib",0.677,2.02E-4,-0.714,1.89E-3,-4.91,{"v":8.91e-07,"d":"8.91E-07"},{"v":7.97e-06,"d":"7.97E-06"},0.162,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["SIRT1","SN_38",0.57,0.00295,-0.787,0.000296,-4.89,{"v":1e-06,"d":"1.00E-06"},{"v":8.97e-06,"d":"8.97E-06"},0.163,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["BCAS4","Bleomycin",-0.446,0.0253,0.756,0.000695,4.2,{"v":2.71e-05,"d":"2.71E-05"},{"v":7.23e-05,"d":"7.23E-05"},0.164,"-/+","Glycopeptide antibiotic, causes DNA breaks","DNA","Conv.Chemo"]
["AP3D1","Clofarabine",-0.477,0.0159,0.739,1.07E-3,4.19,{"v":2.74e-05,"d":"2.74E-05"},{"v":7.38e-05,"d":"7.38E-05"},0.165,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["C1orf112","Ganetespib",0.51,0.00922,-0.718,1.72E-3,-4.19,{"v":2.75e-05,"d":"2.75E-05"},{"v":7.45e-05,"d":"7.45E-05"},0.165,"+/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["ACSS1","GSK2256098",0.102,0.626,0.917,{"v":5.96e-07,"d":"5.96E-07"},4.19,{"v":2.81e-05,"d":"2.81E-05"},{"v":7.48e-05,"d":"7.48E-05"},0.165,"0/+","FAK inhibitor","PTK2","Kinase inhibitor"]
["BZW1","Methotrexate",0.281,0.173,-0.826,{"v":8.19e-05,"d":"8.19E-05"},-4.18,{"v":2.88e-05,"d":"2.88E-05"},{"v":7.53e-05,"d":"7.53E-05"},0.165,"0/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["CASP10","8_amino_adenosine",-0.224,0.282,0.844,{"v":3.94e-05,"d":"3.94E-05"},4.18,{"v":2.89e-05,"d":"2.89E-05"},{"v":7.58e-05,"d":"7.58E-05"},0.165,"0/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["AGO1","Floxuridine",-0.687,1.47E-4,0.55,0.0272,4.18,{"v":2.92e-05,"d":"2.92E-05"},{"v":7.6e-05,"d":"7.60E-05"},0.165,"-/+","Antimetabolite, Analog of 5-fluorouracil","TYMS","Conv.Chemo"]
["ANKRD50","Rocilinostat",0.529,0.00661,-0.703,0.00237,-4.18,{"v":2.93e-05,"d":"2.93E-05"},{"v":7.7e-05,"d":"7.70E-05"},0.165,"+/-","HDAC6 selective inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["CBX4","Tacedinaline",-0.428,0.033,0.763,0.000585,4.17,{"v":2.98e-05,"d":"2.98E-05"},{"v":7.7e-05,"d":"7.70E-05"},0.165,"-/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["ANKRD40","Hydroxyurea",0.524,0.00714,-0.705,0.00228,-4.17,{"v":3.01E-5,"d":"3.01E-05"},{"v":7.82e-05,"d":"7.82E-05"},0.165,"+/-","Antineoplastic agent","RRM1","Conv.Chemo"]
["BRF1","AZD_5438",-0.301,0.143,0.817,1.11E-4,4.17,{"v":3.02e-05,"d":"3.02E-05"},{"v":7.82e-05,"d":"7.82E-05"},0.165,"0/+","CDK1, 2, 9 inhibitor","CDK1;CDK2;CDK9","Kinase inhibitor"]
["ABCC10","TAK_901",-0.577,0.00251,0.663,0.00508,4.17,{"v":3.09e-05,"d":"3.09E-05"},{"v":7.87e-05,"d":"7.87E-05"},0.165,"-/+","Aurora, Src family, JAK3, RTK inhibitor","AURKA;AURKB;JAK3;SRC;CLK2;FGR;LRRK2;YES1;LCK;FYN;ABL1;AXL;ABL2;HCK;RET;FRK;NTRK1;FGFR2","Kinase inhibitor"]
["CC2D1B","OSU_03012",-0.602,0.00146,0.642,0.00739,4.16,{"v":3.12e-05,"d":"3.12E-05"},{"v":7.97e-05,"d":"7.97E-05"},0.165,"-/+","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["APAF1","SN_38",-0.669,0.000254,0.569,0.0214,4.16,{"v":3.18E-5,"d":"3.18E-05"},{"v":8.07e-05,"d":"8.07E-05"},0.165,"-/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["BUB1","Clofarabine",0.628,0.000774,-0.615,0.0112,-4.16,{"v":3.18E-5,"d":"3.18E-05"},{"v":8.15e-05,"d":"8.15E-05"},0.165,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["ASB7","Perifosine",-0.107,0.61,0.873,{"v":9.94e-06,"d":"9.94E-06"},4.16,{"v":3.2e-05,"d":"3.20E-05"},{"v":8.15e-05,"d":"8.15E-05"},0.165,"0/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["ARHGAP23","Idarubicin",0.313,0.128,-0.811,1.37E-4,-4.16,{"v":3.23e-05,"d":"3.23E-05"},{"v":8.15e-05,"d":"8.15E-05"},0.165,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["AKAP8L","Fluorouracil",0.313,0.127,-0.811,0.000139,-4.16,{"v":3.25e-05,"d":"3.25E-05"},{"v":8.15e-05,"d":"8.15E-05"},0.165,"0/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","TYMS","Conv.Chemo"]
["BSCL2","Selumetinib",-0.503,0.0103,0.716,1.81E-3,4.16,{"v":3.25e-05,"d":"3.25E-05"},{"v":8.17e-05,"d":"8.17E-05"},0.165,"-/+","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["ATP5IF1","Tirabrutinib",-0.375,0.0647,0.785,0.000318,4.15,{"v":3.32e-05,"d":"3.32E-05"},{"v":8.17e-05,"d":"8.17E-05"},0.165,"0/+","BTK inhibitor","BTK","Kinase inhibitor"]
["TXNDC9","Carboplatin",0.728,{"v":3.73e-05,"d":"3.73E-05"},-0.587,0.0168,-4.57,{"v":4.98e-06,"d":"4.98E-06"},{"v":1.6e-05,"d":"1.60E-05"},0.165,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["USP20","AT_406",-0.552,0.00421,0.751,0.000804,4.56,{"v":5.05e-06,"d":"5.05E-06"},{"v":1.6e-05,"d":"1.60E-05"},0.165,"-/+","XIAP, cIAP1, cIAP2 inhibitor","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["TRMU","Sepantronium_bromide",-0.598,0.00161,0.719,0.0017,4.56,{"v":5.14e-06,"d":"5.14E-06"},{"v":1.65e-05,"d":"1.65E-05"},0.165,"-/+","Survivin inhibitor","BIRC5","Apoptotic modulator"]
["KLHL26","Perifosine",-0.0423,0.841,-0.931,{"v":1.63e-07,"d":"1.63E-07"},-4.65,{"v":3.39e-06,"d":"3.39E-06"},{"v":1.55e-05,"d":"1.55E-05"},0.166,"0/-","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["FAIM","Clofarabine",0.581,2.31E-3,-0.747,0.000873,-4.66,{"v":3.11e-06,"d":"3.11E-06"},{"v":1.62e-05,"d":"1.62E-05"},0.167,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["FBXO28","Panobinostat",0.667,2.72E-4,-0.677,0.004,-4.65,{"v":3.27E-6,"d":"3.27E-06"},{"v":1.67e-05,"d":"1.67E-05"},0.168,"+/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["IMMP2L","Tamatinib",0.333,0.103,-0.855,{"v":2.47e-05,"d":"2.47E-05"},-4.63,{"v":3.63E-6,"d":"3.63E-06"},{"v":1.62e-05,"d":"1.62E-05"},0.168,"0/-","SYK inhibitor","SYK","Kinase inhibitor"]
["MELK","Prexasertib",0.681,0.000177,-0.654,0.00599,-4.61,{"v":3.95e-06,"d":"3.95E-06"},{"v":1.74e-05,"d":"1.74E-05"},0.168,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["LCP2","Gemcitabine",-0.111,0.596,0.905,{"v":1.4e-06,"d":"1.40E-06"},4.61,{"v":3.97e-06,"d":"3.97E-06"},{"v":1.74e-05,"d":"1.74E-05"},0.168,"0/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["MBOAT7","Raltitrexed",-0.698,1.05E-4,0.632,0.00856,4.6,{"v":4.24e-06,"d":"4.24E-06"},{"v":1.77E-5,"d":"1.77E-05"},0.168,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["MBOAT7","8_amino_adenosine",-0.438,0.0287,0.813,0.000128,4.59,{"v":4.43e-06,"d":"4.43E-06"},{"v":1.79e-05,"d":"1.79E-05"},0.168,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["MCPH1","Cytarabine.Idarubicin",0.768,{"v":7.34E-6,"d":"7.34E-06"},-0.529,0.0351,-4.59,{"v":4.49e-06,"d":"4.49E-06"},{"v":1.84E-5,"d":"1.84E-05"},0.168,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["CAPN7","Prexasertib",-0.618,0.00099,0.623,0.01,4.15,{"v":3.35e-05,"d":"3.35E-05"},{"v":8.47e-05,"d":"8.47E-05"},0.17,"-/+","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["CBX6","Carboplatin",-0.39,0.0538,0.777,0.000399,4.14,{"v":3.41e-05,"d":"3.41E-05"},{"v":8.52e-05,"d":"8.52E-05"},0.17,"0/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["GNG2","BX_912",-0.731,{"v":3.37e-05,"d":"3.37E-05"},0.601,0.0138,4.64,{"v":3.41E-6,"d":"3.41E-06"},{"v":1.74e-05,"d":"1.74E-05"},0.17,"-/+","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["ARHGEF2","Vismodegib",0.0313,0.882,-0.889,{"v":4.07E-6,"d":"4.07E-06"},-4.14,{"v":3.42e-05,"d":"3.42E-05"},{"v":8.67e-05,"d":"8.67E-05"},0.171,"0/-","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["ADD3","AZD1152_HQPA",-0.196,0.348,0.848,{"v":3.4E-5,"d":"3.40E-05"},4.13,{"v":3.59e-05,"d":"3.59E-05"},{"v":8.67e-05,"d":"8.67E-05"},0.171,"0/+","Aurora B inhibitor","AURKB","Kinase inhibitor"]
["RDH10","Finasteride",-0.339,0.0971,0.874,{"v":9.68e-06,"d":"9.68E-06"},4.87,{"v":1.13E-6,"d":"1.13E-06"},{"v":7.73e-06,"d":"7.73E-06"},0.174,"0/+","type II 5-alpha reductase inhibitor","SRD5A2","Hormone therapy"]
["RELL1","Mitoxantrone",-0.532,0.00625,0.802,0.000188,4.85,{"v":1.25e-06,"d":"1.25E-06"},{"v":8.47e-06,"d":"8.47E-06"},0.174,"-/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["RAB5C","Prexasertib",-0.873,{"v":1.29E-8,"d":"1.29E-08"},0.334,0.206,4.84,{"v":1.33E-6,"d":"1.33E-06"},{"v":8.47e-06,"d":"8.47E-06"},0.174,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["RAB5C","Cabazitaxel",-0.806,{"v":1.14e-06,"d":"1.14E-06"},0.508,0.0448,4.79,{"v":1.67e-06,"d":"1.67E-06"},{"v":9.72e-06,"d":"9.72E-06"},0.174,"-/+","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["PRKAR1A","Silmitasertib",0.0123,0.954,0.934,{"v":1.27e-07,"d":"1.27E-07"},4.79,{"v":1.7E-6,"d":"1.70E-06"},{"v":9.72e-06,"d":"9.72E-06"},0.174,"0/+","CSNK2A1 inhibitor","CSNK2A1","Kinase inhibitor"]
["RAB34","Losmapimod",-0.227,0.275,0.893,{"v":3.21e-06,"d":"3.21E-06"},4.77,{"v":1.86E-6,"d":"1.86E-06"},{"v":1.05e-05,"d":"1.05E-05"},0.174,"0/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["PPIF","Quizartinib",0.808,{"v":1.07e-06,"d":"1.07E-06"},-0.495,0.0514,-4.75,{"v":2.02e-06,"d":"2.02E-06"},{"v":1.1E-5,"d":"1.10E-05"},0.174,"+/0","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["RELL1","Oxaliplatin",-0.533,0.00607,0.788,0.000291,4.74,{"v":2.09e-06,"d":"2.09E-06"},{"v":1.15E-5,"d":"1.15E-05"},0.174,"-/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["PPP1R12C","Tozasertib",-0.65,0.000439,0.709,0.00212,4.74,{"v":2.11e-06,"d":"2.11E-06"},{"v":1.15E-5,"d":"1.15E-05"},0.174,"-/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["ROR1","Pracinostat",0.697,0.000109,-0.662,0.00519,-4.74,{"v":2.14e-06,"d":"2.14E-06"},{"v":1.2E-5,"d":"1.20E-05"},0.174,"+/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["RAD51","Raltitrexed",0.724,{"v":4.22e-05,"d":"4.22E-05"},-0.619,0.0106,-4.69,{"v":2.74E-6,"d":"2.74E-06"},{"v":1.27E-5,"d":"1.27E-05"},0.174,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["SEC11A","Ridaforolimus",-0.54,0.00535,0.776,4.08E-4,4.69,{"v":2.78e-06,"d":"2.78E-06"},{"v":1.3e-05,"d":"1.30E-05"},0.174,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["RELL1","Idarubicin",-0.56,3.62E-3,0.764,0.000567,4.68,{"v":2.81e-06,"d":"2.81E-06"},{"v":1.35e-05,"d":"1.35E-05"},0.174,"-/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["RDH10","Vismodegib",-0.285,0.167,0.871,{"v":1.1E-5,"d":"1.10E-05"},4.67,{"v":3.07e-06,"d":"3.07E-06"},{"v":1.45E-5,"d":"1.45E-05"},0.174,"0/+","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["RAB11B","IOX_1",-0.563,0.00337,0.759,0.000655,4.66,{"v":3.13e-06,"d":"3.13E-06"},{"v":1.45E-5,"d":"1.45E-05"},0.174,"-/+","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["RAD51","Cytarabine.Idarubicin",0.52,0.0077,-0.783,0.00034,-4.65,{"v":3.25e-06,"d":"3.25E-06"},{"v":1.47E-5,"d":"1.47E-05"},0.174,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["RRM2B","Tivantinib",-0.532,0.00615,0.775,0.00042,4.65,{"v":3.32E-6,"d":"3.32E-06"},{"v":1.52E-5,"d":"1.52E-05"},0.174,"-/+","MET inhibitor","MET","Kinase inhibitor"]
["RELB","Losmapimod",-0.113,0.592,0.907,{"v":1.27e-06,"d":"1.27E-06"},4.64,{"v":3.5e-06,"d":"3.50E-06"},{"v":1.57e-05,"d":"1.57E-05"},0.174,"0/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["EIF2AK4","Paclitaxel",-0.608,0.00126,0.724,0.00152,4.64,{"v":3.57e-06,"d":"3.57E-06"},{"v":1.84E-5,"d":"1.84E-05"},0.175,"-/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["TPM2","Pevonedistat",-0.461,0.0202,0.795,2.33E-4,4.53,{"v":5.98e-06,"d":"5.98E-06"},{"v":1.85e-05,"d":"1.85E-05"},0.176,"-/+","NAE inhibitor","NAE1","Metabolic modifier"]
["ZNF711","Dabrafenib",0.234,0.26,-0.873,{"v":1.03E-5,"d":"1.03E-05"},-4.53,{"v":6.02E-6,"d":"6.02E-06"},{"v":1.85e-05,"d":"1.85E-05"},0.176,"0/-","BRAF(V600E) inhibitor","BRAF;RAF1","Kinase inhibitor"]
["FGFR1OP","Carboplatin",0.699,{"v":1E-4,"d":"1.00E-04"},-0.636,0.00804,-4.63,{"v":3.75e-06,"d":"3.75E-06"},{"v":1.97e-05,"d":"1.97E-05"},0.177,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["GMNN","Pemetrexed",0.747,{"v":1.77E-5,"d":"1.77E-05"},-0.57,0.0212,-4.61,{"v":3.95e-06,"d":"3.95E-06"},{"v":1.97e-05,"d":"1.97E-05"},0.177,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["EIF2AK4","Cabazitaxel",-0.587,0.00204,0.735,0.00118,4.61,{"v":4.06e-06,"d":"4.06E-06"},{"v":2.02E-5,"d":"2.02E-05"},0.177,"-/+","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["GOLGA2","ZSTK474",-0.185,0.375,0.89,{"v":3.98E-6,"d":"3.98E-06"},4.6,{"v":4.32e-06,"d":"4.32E-06"},{"v":2.07e-05,"d":"2.07E-05"},0.177,"0/+","PI3K gamma selective inhibitor","PIK3CG","Kinase inhibitor"]
["EIF4G2","Pemetrexed",0.719,{"v":5.1E-5,"d":"5.10E-05"},-0.605,0.0131,-4.59,{"v":4.39e-06,"d":"4.39E-06"},{"v":2.12E-5,"d":"2.12E-05"},0.177,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["GDAP2","ML390",-0.339,0.0972,0.848,{"v":3.28e-05,"d":"3.28E-05"},4.58,{"v":4.58e-06,"d":"4.58E-06"},{"v":2.17e-05,"d":"2.17E-05"},0.177,"0/+","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["EIF4G2","Clofarabine",0.592,1.82E-3,-0.727,1.42E-3,-4.58,{"v":4.6E-6,"d":"4.60E-06"},{"v":2.22e-05,"d":"2.22E-05"},0.177,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["PLEKHM3","Losmapimod",-0.342,0.0939,0.942,{"v":4.94e-08,"d":"4.94E-08"},6.04,{"v":1.51E-9,"d":"1.51E-09"},{"v":4.98e-07,"d":"4.98E-07"},0.177,"0/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["OIP5","Gemcitabine",0.648,0.000456,-0.833,{"v":6.11e-05,"d":"6.11E-05"},-5.63,{"v":1.75e-08,"d":"1.75E-08"},{"v":1.5E-6,"d":"1.50E-06"},0.177,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["MSN","Cytarabine",-0.755,{"v":1.27E-5,"d":"1.27E-05"},0.743,0.000969,5.55,{"v":2.79e-08,"d":"2.79E-08"},{"v":1.99E-6,"d":"1.99E-06"},0.177,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["PLEKHM3","Mitomycin_C",-0.14,0.505,0.942,{"v":4.89e-08,"d":"4.89E-08"},5.43,{"v":5.67e-08,"d":"5.67E-08"},{"v":2.99e-06,"d":"2.99E-06"},0.177,"0/+","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["PIP4K2B","SN_38",-0.588,2E-3,0.835,{"v":5.61e-05,"d":"5.61E-05"},5.38,{"v":7.65e-08,"d":"7.65E-08"},{"v":3.74e-06,"d":"3.74E-06"},0.177,"-/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["PLCB2","8_amino_adenosine",-0.358,0.0789,0.9,{"v":2.04E-6,"d":"2.04E-06"},5.28,{"v":1.29E-7,"d":"1.29E-07"},{"v":4.49e-06,"d":"4.49E-06"},0.177,"0/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["POLK","Gedatolisib",-0.315,0.125,0.907,{"v":1.3E-6,"d":"1.30E-06"},5.24,{"v":1.59e-07,"d":"1.59E-07"},{"v":4.73e-06,"d":"4.73E-06"},0.177,"0/+","PI3K, mTOR inhibitor","PIK3CA;PIK3CG;MTOR","Kinase inhibitor"]
["PLEKHM3","Perifosine",0.147,0.484,0.961,{"v":3.3e-09,"d":"3.30E-09"},5.18,{"v":2.24e-07,"d":"2.24E-07"},{"v":4.98e-06,"d":"4.98E-06"},0.177,"0/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["MTFR1","BMS_911543",-0.309,0.133,0.903,{"v":1.62e-06,"d":"1.62E-06"},5.18,{"v":2.28E-7,"d":"2.28E-07"},{"v":4.98e-06,"d":"4.98E-06"},0.177,"0/+","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["MTFP1","Tasquinimod",-0.828,{"v":3.17e-07,"d":"3.17E-07"},0.547,0.0284,5.14,{"v":2.79E-7,"d":"2.79E-07"},{"v":5.48E-6,"d":"5.48E-06"},0.177,"-/+","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["OSER1","BMS_754807",0.213,0.306,-0.917,{"v":5.69e-07,"d":"5.69E-07"},-5.11,{"v":3.2e-07,"d":"3.20E-07"},{"v":5.98e-06,"d":"5.98E-06"},0.177,"0/-","IGF1R inhibitor","IGF1R","Kinase inhibitor"]
["PBK","Cytarabine",0.837,{"v":1.81e-07,"d":"1.81E-07"},-0.516,0.0408,-5.09,{"v":3.49e-07,"d":"3.49E-07"},{"v":5.98e-06,"d":"5.98E-06"},0.177,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["TIMM29","Mitomycin_C",0.11,0.599,-0.92,{"v":4.37e-07,"d":"4.37E-07"},-4.87,{"v":1.13E-6,"d":"1.13E-06"},{"v":1.02e-05,"d":"1.02E-05"},0.177,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["C4orf3","Dactinomycin",-0.413,0.04,0.764,0.000573,4.13,{"v":3.62e-05,"d":"3.62E-05"},{"v":9.15e-05,"d":"9.15E-05"},0.178,"-/+","RNA and DNA synthesis inhibitor","DNA","Conv.Chemo"]
["ATP5F1B","Filanesib",-0.338,0.0985,0.798,2.13E-4,4.13,{"v":3.65E-5,"d":"3.65E-05"},{"v":9.15e-05,"d":"9.15E-05"},0.178,"0/+","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["ANO10","AT13148",-0.445,0.0258,0.746,0.000904,4.12,{"v":3.73e-05,"d":"3.73E-05"},{"v":9.25e-05,"d":"9.25E-05"},0.179,"-/+","p70S6K, PKA, ROCK (AKT) inhibitor","AKT1;AKT2;AKT3;RPS6KB1;ROCK1;ROCK2;PRKACA;PRKACB;PRKACG","Kinase inhibitor"]
["FAAP20","Decitabine",0.385,0.0577,-0.832,{"v":6.44e-05,"d":"6.44E-05"},-4.57,{"v":4.81e-06,"d":"4.81E-06"},{"v":2.29e-05,"d":"2.29E-05"},0.179,"0/-","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["VPS35","GSK_461364",-0.72,{"v":4.99E-5,"d":"4.99E-05"},0.587,0.0167,4.52,{"v":6.22e-06,"d":"6.22E-06"},{"v":1.95E-5,"d":"1.95E-05"},0.18,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["ABRAXAS1","Bosutinib",0.192,0.359,-0.848,{"v":3.35e-05,"d":"3.35E-05"},-4.12,{"v":3.73e-05,"d":"3.73E-05"},{"v":9.44e-05,"d":"9.44E-05"},0.181,"0/-","ABL, Src inhibitor","ABL1;LYN;HCK;SRC;EPHB2;NTRK1;NTRK2;TXK","Kinase inhibitor"]
["C1orf112","Cabazitaxel",0.738,{"v":2.55E-5,"d":"2.55E-05"},-0.459,0.074,-4.12,{"v":3.79E-5,"d":"3.79E-05"},{"v":9.44e-05,"d":"9.44E-05"},0.181,"+/0","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["AAK1","AZD1208",-0.624,0.000853,0.609,0.0122,4.12,{"v":3.86e-05,"d":"3.86E-05"},{"v":9.52e-05,"d":"9.52E-05"},0.181,"-/+","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["RNF213","Topotecan",-0.142,0.499,0.9,{"v":2.01e-06,"d":"2.01E-06"},4.62,{"v":3.82e-06,"d":"3.82E-06"},{"v":1.69e-05,"d":"1.69E-05"},0.182,"0/+","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["RNF213","Clofarabine",-0.388,0.0554,0.835,{"v":5.61e-05,"d":"5.61E-05"},4.62,{"v":3.9e-06,"d":"3.90E-06"},{"v":1.77E-5,"d":"1.77E-05"},0.182,"0/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["RBM15","Losmapimod",-0.308,0.134,0.861,{"v":1.88E-5,"d":"1.88E-05"},4.61,{"v":3.95e-06,"d":"3.95E-06"},{"v":1.79e-05,"d":"1.79E-05"},0.182,"0/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["ACO2","TGX_221",-0.327,0.11,0.8,0.000197,4.11,{"v":3.89e-05,"d":"3.89E-05"},{"v":9.67e-05,"d":"9.67E-05"},0.183,"0/+","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["AP1B1","Alisertib",-0.554,0.00407,0.672,0.00435,4.11,{"v":3.93E-5,"d":"3.93E-05"},{"v":9.72e-05,"d":"9.72E-05"},0.183,"-/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["TBCC","Bafetinib",-0.519,0.00782,0.806,1.63E-4,4.83,{"v":1.34e-06,"d":"1.34E-06"},{"v":1.17E-5,"d":"1.17E-05"},0.183,"-/+","ABL, Lyn inhibitor","ABL1;LYN","Kinase inhibitor"]
["TIGD2","Tivozanib",0.113,0.59,-0.918,{"v":5.57e-07,"d":"5.57E-07"},-4.82,{"v":1.41e-06,"d":"1.41E-06"},{"v":1.2E-5,"d":"1.20E-05"},0.183,"0/-","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["SFT2D3","Oxaliplatin",0.692,1.27E-4,-0.682,3.62E-3,-4.81,{"v":1.48E-6,"d":"1.48E-06"},{"v":1.25e-05,"d":"1.25E-05"},0.183,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["STX7","Ribociclib",-0.691,0.000129,0.679,3.79E-3,4.8,{"v":1.6e-06,"d":"1.60E-06"},{"v":1.27E-5,"d":"1.27E-05"},0.183,"-/+","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["TDP2","Gemcitabine",0.464,0.0196,-0.826,{"v":8.14E-5,"d":"8.14E-05"},-4.79,{"v":1.65e-06,"d":"1.65E-06"},{"v":1.32e-05,"d":"1.32E-05"},0.183,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["TNFRSF1B","Triapine",-0.552,0.0042,0.781,0.000353,4.77,{"v":1.81E-6,"d":"1.81E-06"},{"v":1.4E-5,"d":"1.40E-05"},0.183,"-/+","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["TIGD2","Agerafenib_CEP_32496",0.156,0.455,-0.906,{"v":1.32e-06,"d":"1.32E-06"},-4.76,{"v":1.97e-06,"d":"1.97E-06"},{"v":1.5E-5,"d":"1.50E-05"},0.183,"0/-","BRAF(V600E) inhibitor","BRAF;RAF1;KIT;RET;LCK;ABL1;PDGFRB;CSF1R;MET;EGFR;KDR;EPHA2","Kinase inhibitor"]
["SIGIRR","Cytarabine",-0.679,0.000189,0.674,0.00417,4.71,{"v":2.53e-06,"d":"2.53E-06"},{"v":1.69e-05,"d":"1.69E-05"},0.183,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["TMEM192","GSK923295",-0.449,0.0245,0.822,{"v":9.36e-05,"d":"9.36E-05"},4.7,{"v":2.54e-06,"d":"2.54E-06"},{"v":1.69e-05,"d":"1.69E-05"},0.183,"-/+","CENP-E inhibitor","CENPE","Kinesin inhibitor"]
["SLC38A5","Tipifarnib",0.52,0.00775,-0.789,0.000279,-4.7,{"v":2.57E-6,"d":"2.57E-06"},{"v":1.69e-05,"d":"1.69E-05"},0.183,"+/-","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["SIPA1","Everolimus",-0.196,0.349,0.892,{"v":3.35e-06,"d":"3.35E-06"},4.66,{"v":3.09e-06,"d":"3.09E-06"},{"v":1.97e-05,"d":"1.97E-05"},0.183,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["TDP2","Cytarabine",0.541,0.00519,-0.771,4.75E-4,-4.65,{"v":3.25e-06,"d":"3.25E-06"},{"v":1.99e-05,"d":"1.99E-05"},0.183,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["SPECC1L","Idelalisib",0.479,0.0154,-0.803,0.000182,-4.65,{"v":3.27E-6,"d":"3.27E-06"},{"v":1.99e-05,"d":"1.99E-05"},0.183,"+/-","PI3K inhibitor, p110-selective","PIK3CD","Kinase inhibitor"]
["SPN","CC_223",-0.541,0.00518,0.77,0.000479,4.65,{"v":3.28e-06,"d":"3.28E-06"},{"v":1.99e-05,"d":"1.99E-05"},0.183,"-/+","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["SNX22","Rocilinostat",0.531,0.00627,-0.775,4.17E-4,-4.65,{"v":3.36E-6,"d":"3.36E-06"},{"v":2.02E-5,"d":"2.02E-05"},0.183,"+/-","HDAC6 selective inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["TMEM192","Rigosertib",-0.539,0.00541,0.769,0.000502,4.63,{"v":3.63E-6,"d":"3.63E-06"},{"v":2.09E-5,"d":"2.09E-05"},0.183,"-/+","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["TAF10","Pomalidomide",-0.701,{"v":9.49e-05,"d":"9.49E-05"},0.632,0.00861,4.61,{"v":3.94e-06,"d":"3.94E-06"},{"v":2.22e-05,"d":"2.22E-05"},0.183,"-/+","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["TMEM102","Tubastatin_A",0.458,0.0212,-0.806,0.000161,-4.61,{"v":4.06e-06,"d":"4.06E-06"},{"v":2.27E-5,"d":"2.27E-05"},0.183,"+/-","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["SRPRA","Megestrol_acetate",0.6,0.00152,-0.724,0.00151,-4.6,{"v":4.2e-06,"d":"4.20E-06"},{"v":2.29e-05,"d":"2.29E-05"},0.183,"+/-","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["STYX","Pomalidomide",-0.563,0.00336,0.749,0.000835,4.6,{"v":4.23e-06,"d":"4.23E-06"},{"v":2.29e-05,"d":"2.29E-05"},0.183,"-/+","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["STAT5A","BX_912",-0.405,0.0448,0.826,{"v":8.03E-5,"d":"8.03E-05"},4.59,{"v":4.47e-06,"d":"4.47E-06"},{"v":2.42e-05,"d":"2.42E-05"},0.183,"-/+","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["TDP2","Cytarabine.Idarubicin",0.474,0.0166,-0.797,2.22E-4,-4.59,{"v":4.5e-06,"d":"4.50E-06"},{"v":2.42e-05,"d":"2.42E-05"},0.183,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["SOS1","Glesatinib",-0.489,0.0131,0.789,2.81E-4,4.58,{"v":4.61e-06,"d":"4.61E-06"},{"v":2.47e-05,"d":"2.47E-05"},0.183,"-/+","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["SIRT1","Cytarabine",0.692,1.27E-4,-0.635,0.00827,-4.58,{"v":4.73e-06,"d":"4.73E-06"},{"v":2.52e-05,"d":"2.52E-05"},0.183,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["TGS1","AMG319",0.628,0.00078,-0.697,0.00271,-4.57,{"v":4.89e-06,"d":"4.89E-06"},{"v":2.57e-05,"d":"2.57E-05"},0.183,"+/-","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["SNX22","Pracinostat",0.692,1.27E-4,-0.633,0.00848,-4.57,{"v":4.9100000000000004E-6,"d":"4.91E-06"},{"v":2.57e-05,"d":"2.57E-05"},0.183,"+/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["TMEM131L","Cytarabine.Idarubicin",0.635,0.000652,-0.689,0.00317,-4.56,{"v":5.13E-6,"d":"5.13E-06"},{"v":2.59e-05,"d":"2.59E-05"},0.183,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["STK11IP","ABT_751",-0.724,{"v":4.36e-05,"d":"4.36E-05"},0.591,0.0159,4.56,{"v":5.19e-06,"d":"5.19E-06"},{"v":2.62E-5,"d":"2.62E-05"},0.183,"-/+","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["SLC25A20","Thioguanine",-0.437,0.0289,0.809,0.000148,4.55,{"v":5.31E-6,"d":"5.31E-06"},{"v":2.67e-05,"d":"2.67E-05"},0.183,"-/+","Antimetabolite, Purine analog","DNMT1","Conv.Chemo"]
["SMIM20","Merestinib",0.277,0.179,-0.864,{"v":1.63E-5,"d":"1.63E-05"},-4.55,{"v":5.34e-06,"d":"5.34E-06"},{"v":2.67e-05,"d":"2.67E-05"},0.183,"0/-","MET inhibitor","MET","Kinase inhibitor"]
["TMEM39A","Gilteritinib",-0.227,0.276,0.876,{"v":8.54e-06,"d":"8.54E-06"},4.55,{"v":5.47e-06,"d":"5.47E-06"},{"v":2.72E-5,"d":"2.72E-05"},0.183,"0/+","FLT3, AXL inhibitor","FLT3","Kinase inhibitor"]
["SPAG5","Pemetrexed",0.839,{"v":1.66E-7,"d":"1.66E-07"},-0.354,0.179,-4.53,{"v":5.81e-06,"d":"5.81E-06"},{"v":2.82e-05,"d":"2.82E-05"},0.183,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["TOM1L2","AZD8055",-0.406,0.0438,0.818,1.07E-4,4.53,{"v":6.02E-6,"d":"6.02E-06"},{"v":2.87E-5,"d":"2.87E-05"},0.183,"-/+","mTOR inhibitor","MTOR","Kinase inhibitor"]
["TIGD2","Bosutinib",0.14,0.504,-0.894,{"v":3.03e-06,"d":"3.03E-06"},-4.52,{"v":6.05e-06,"d":"6.05E-06"},{"v":2.87E-5,"d":"2.87E-05"},0.183,"0/-","ABL, Src inhibitor","ABL1;LYN;HCK;SRC;EPHB2;NTRK1;NTRK2;TXK","Kinase inhibitor"]
["CKAP5","Cytarabine",0.691,0.000131,-0.67,0.00454,-4.75,{"v":2.08E-6,"d":"2.08E-06"},{"v":1.59E-5,"d":"1.59E-05"},0.184,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["CTNND1","AZD3965",0.0231,0.913,0.933,{"v":1.37E-7,"d":"1.37E-07"},4.74,{"v":2.16e-06,"d":"2.16E-06"},{"v":1.62e-05,"d":"1.62E-05"},0.184,"0/+","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["DENND5B","Megestrol_acetate",-0.439,0.028,0.827,{"v":7.8e-05,"d":"7.80E-05"},4.72,{"v":2.41e-06,"d":"2.41E-06"},{"v":1.79e-05,"d":"1.79E-05"},0.184,"-/+","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["EEA1","CC_223",-0.52,0.00773,0.789,0.000279,4.7,{"v":2.56e-06,"d":"2.56E-06"},{"v":1.89e-05,"d":"1.89E-05"},0.184,"-/+","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["DDRGK1","VS_4718",0.546,0.00478,-0.775,0.000421,-4.7,{"v":2.57E-6,"d":"2.57E-06"},{"v":1.89e-05,"d":"1.89E-05"},0.184,"+/-","FAK inhibitor","PTK2","Kinase inhibitor"]
["EEF1A1","SN_38",0.443,0.0265,-0.824,{"v":8.74e-05,"d":"8.74E-05"},-4.7,{"v":2.58e-06,"d":"2.58E-06"},{"v":1.89e-05,"d":"1.89E-05"},0.184,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["DNAJA1","Midostaurin",0.583,0.0022,-0.751,0.000797,-4.7,{"v":2.64e-06,"d":"2.64E-06"},{"v":1.89e-05,"d":"1.89E-05"},0.184,"+/-","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["CEBPG","Perifosine",-0.411,0.0412,0.835,{"v":5.61e-05,"d":"5.61E-05"},4.7,{"v":2.66e-06,"d":"2.66E-06"},{"v":1.89e-05,"d":"1.89E-05"},0.184,"-/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["DDX60","Cladribine",-0.502,0.0106,0.797,0.000219,4.69,{"v":2.7E-6,"d":"2.70E-06"},{"v":1.89e-05,"d":"1.89E-05"},0.184,"-/+","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["ABHD16A","ABT_751",-0.646,0.000481,0.584,0.0176,4.11,{"v":4e-05,"d":"4.00E-05"},{"v":9.89e-05,"d":"9.89E-05"},0.185,"-/+","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["BUB1B","Cytarabine",0.763,{"v":9.25e-06,"d":"9.25E-06"},-0.408,0.117,-4.1,{"v":4.05e-05,"d":"4.05E-05"},{"v":9.99e-05,"d":"9.99E-05"},0.185,"+/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["BMPR1A","Quizartinib",0.416,0.0388,-0.759,0.000656,-4.1,{"v":4.06e-05,"d":"4.06E-05"},1.01E-4,0.185,"+/-","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["CALHM2","Cladribine",-0.252,0.225,0.827,{"v":7.79e-05,"d":"7.79E-05"},4.1,{"v":4.07E-5,"d":"4.07E-05"},1.02E-4,0.185,"0/+","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["AC093323.1","GSK_1070916",0.2,0.337,-0.843,{"v":4.09e-05,"d":"4.09E-05"},-4.1,{"v":4.1E-5,"d":"4.10E-05"},1.02E-4,0.185,"0/-","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["ABRAXAS1","FRAX486",0.305,0.139,-0.808,1.54E-4,-4.1,{"v":4.1E-5,"d":"4.10E-05"},1.02E-4,0.185,"0/-","PAK1, 2, 3 inhibitor","PAK1","Kinase inhibitor"]
["ARFGAP2","Lonafarnib",0.506,0.00991,-0.705,0.00229,-4.1,{"v":4.14e-05,"d":"4.14E-05"},1.02E-4,0.185,"+/-","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["ARHGEF40","Vandetanib",-0.423,0.035,0.754,0.000747,4.1,{"v":4.19e-05,"d":"4.19E-05"},1.03E-4,0.186,"-/+","VEGFR, EGFR, RET inhibitor","KDR;FLT4;EGFR;RET","Kinase inhibitor"]
["AC091230.1","8_amino_adenosine",-0.563,0.00336,0.661,5.28E-3,4.1,{"v":4.2e-05,"d":"4.20E-05"},0.000104,0.186,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["ARHGAP23","Daunorubicin",0.266,0.199,-0.821,{"v":9.85e-05,"d":"9.85E-05"},-4.09,{"v":4.29e-05,"d":"4.29E-05"},0.000104,0.186,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["APOE","Mercaptopurine",-0.662,0.000312,0.561,0.0237,4.09,{"v":4.3e-05,"d":"4.30E-05"},1.05E-4,0.186,"-/+","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["ALDH5A1","GSK_461364",-0.503,0.0104,0.705,0.00228,4.09,{"v":4.32E-5,"d":"4.32E-05"},1.05E-4,0.186,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["BABAM2","Merestinib",0.408,0.0431,-0.76,0.000628,-4.09,{"v":4.36e-05,"d":"4.36E-05"},1.06E-4,0.186,"+/-","MET inhibitor","MET","Kinase inhibitor"]
["CASP10","AT9283",-0.547,0.00466,0.672,0.00433,4.09,{"v":4.41e-05,"d":"4.41E-05"},1.07E-4,0.186,"-/+","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["CAPZB","Tamatinib",-0.377,0.0634,0.774,0.000433,4.08,{"v":4.54e-05,"d":"4.54E-05"},1.07E-4,0.186,"0/+","SYK inhibitor","SYK","Kinase inhibitor"]
["KIDINS220","Cytarabine",0.652,4.08E-4,-0.674,0.00423,-4.56,{"v":5e-06,"d":"5.00E-06"},{"v":2.09E-5,"d":"2.09E-05"},0.186,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ALDH5A1","Tipifarnib",-0.447,0.0251,0.737,0.00112,4.08,{"v":4.6E-5,"d":"4.60E-05"},1.11E-4,0.188,"-/+","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["APAF1","Gemcitabine",-0.578,0.0025,0.645,0.00698,4.08,{"v":4.6E-5,"d":"4.60E-05"},1.12E-4,0.188,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["AKR1A1","Cladribine",-0.73,{"v":3.42e-05,"d":"3.42E-05"},0.458,0.0746,4.07,{"v":4.71E-5,"d":"4.71E-05"},1.13E-4,0.188,"-/0","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["C12orf45","8_amino_adenosine",0.194,0.353,-0.842,{"v":4.34e-05,"d":"4.34E-05"},-4.07,{"v":4.72e-05,"d":"4.72E-05"},0.000114,0.188,"0/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["ARMH3","Volasertib",-0.439,0.0281,0.74,0.00104,4.07,{"v":4.77e-05,"d":"4.77E-05"},0.000114,0.188,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["ARHGEF40","BMS_911543",-0.307,0.135,0.802,1.84E-4,4.07,{"v":4.77e-05,"d":"4.77E-05"},1.15E-4,0.188,"0/+","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["AAK1","PIM_447",-0.427,0.0335,0.747,0.000881,4.07,{"v":4.8e-05,"d":"4.80E-05"},1.15E-4,0.188,"-/+","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["AURKB","Prexasertib",0.717,{"v":5.51e-05,"d":"5.51E-05"},-0.478,0.0612,-4.06,{"v":4.83e-05,"d":"4.83E-05"},1.16E-4,0.188,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["APOBEC3F","8_amino_adenosine",-0.179,0.391,0.845,{"v":3.72e-05,"d":"3.72E-05"},4.06,{"v":4.85E-5,"d":"4.85E-05"},1.16E-4,0.188,"0/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["AP3S1","SN_38",-0.514,0.00857,0.693,0.00295,4.06,{"v":4.86e-05,"d":"4.86E-05"},1.17E-4,0.188,"-/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["ATP2B4","Cytarabine",-0.462,0.0201,0.726,0.00145,4.06,{"v":4.9e-05,"d":"4.90E-05"},1.18E-4,0.188,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ARHGAP18","Temsirolimus",-0.276,0.182,0.813,1.27E-4,4.06,{"v":4.92e-05,"d":"4.92E-05"},1.18E-4,0.188,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ATP5IF1","Daporinad",-0.565,0.00328,0.653,6.13E-3,4.06,{"v":4.95e-05,"d":"4.95E-05"},1.18E-4,0.188,"-/+","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["BSCL2","SCH772984",-0.483,0.0144,0.712,0.00196,4.06,{"v":4.98e-05,"d":"4.98E-05"},1.18E-4,0.188,"-/+","ERK1 and 2 inhibitor","MAPK3","Kinase inhibitor"]
["APAF1","Pemetrexed",-0.623,0.000876,0.597,0.0146,4.06,{"v":5e-05,"d":"5.00E-05"},0.000119,0.188,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["ARF4","Vinblastine",0.367,0.0715,-0.776,4.15E-4,-4.05,{"v":5.01e-05,"d":"5.01E-05"},0.000119,0.188,"0/-","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["C1QBP","Agerafenib_CEP_32496",0.346,0.0902,-0.785,0.00032,-4.05,{"v":5.04e-05,"d":"5.04E-05"},0.000119,0.188,"0/-","BRAF(V600E) inhibitor","BRAF;RAF1;KIT;RET;LCK;ABL1;PDGFRB;CSF1R;MET;EGFR;KDR;EPHA2","Kinase inhibitor"]
["C10orf88","Daunorubicin",0.614,0.0011,-0.605,0.013,-4.05,{"v":5.14e-05,"d":"5.14E-05"},1.2E-4,0.188,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["CCDC186","PD0325901",0.407,0.0432,-0.755,0.00073,-4.05,{"v":5.17e-05,"d":"5.17E-05"},1.22E-4,0.188,"+/-","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["CCDC124","BMS863233",0.324,0.114,-0.793,0.000247,-4.05,{"v":5.18e-05,"d":"5.18E-05"},1.22E-4,0.188,"0/-","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["ATP5F1A","Filanesib",-0.354,0.0829,0.78,0.000366,4.04,{"v":5.25e-05,"d":"5.25E-05"},1.22E-4,0.188,"0/+","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["CCDC47","Erlotinib",-0.372,0.0671,0.771,0.000465,4.04,{"v":5.26e-05,"d":"5.26E-05"},0.000123,0.188,"0/+","EGFR inhibitor","EGFR","Kinase inhibitor"]
["BUD13","Verdinexor",0.362,0.0755,-0.776,0.000411,-4.04,{"v":5.3e-05,"d":"5.30E-05"},0.000123,0.188,"0/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["ADA2","Cytarabine.Idarubicin",-0.396,0.0503,0.759,0.000651,4.04,{"v":5.41E-5,"d":"5.41E-05"},0.000124,0.188,"0/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["ACP2","SCH772984",-0.608,1.25E-3,0.608,0.0125,4.04,{"v":5.42e-05,"d":"5.42E-05"},1.25E-4,0.188,"-/+","ERK1 and 2 inhibitor","MAPK3","Kinase inhibitor"]
["C11orf68","Resminostat",-0.244,0.239,0.822,{"v":9.41e-05,"d":"9.41E-05"},4.04,{"v":5.44e-05,"d":"5.44E-05"},1.25E-4,0.188,"0/+","HDAC1, 3, 6 inhibitor","HDAC1;HDAC3;HDAC6","Differentiating.epigenetic modifier"]
["AKAP5","Methotrexate",0.466,0.019,-0.719,0.00168,-4.03,{"v":5.52E-5,"d":"5.52E-05"},1.26E-4,0.188,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["ATP5MD","Alisertib",-0.505,0.0101,0.693,0.0029,4.03,{"v":5.57e-05,"d":"5.57E-05"},1.27E-4,0.188,"-/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["AC091230.1","Tozasertib",-0.44,0.0279,0.734,0.0012,4.03,{"v":5.59e-05,"d":"5.59E-05"},0.000128,0.188,"-/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["BCLAF1","Everolimus",0.327,0.111,-0.79,0.000274,-4.03,{"v":5.6e-05,"d":"5.60E-05"},0.000128,0.188,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["AGPAT2","Everolimus",-0.272,0.188,0.811,0.000138,4.03,{"v":5.6e-05,"d":"5.60E-05"},0.000128,0.188,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["CBX6","Etoposide",-0.438,0.0284,0.735,0.00119,4.03,{"v":5.64e-05,"d":"5.64E-05"},0.000128,0.188,"-/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["AGPAT2","Sirolimus",-0.202,0.334,0.835,{"v":5.74e-05,"d":"5.74E-05"},4.03,{"v":5.68e-05,"d":"5.68E-05"},0.000129,0.188,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ACBD3","Dactinomycin",0.481,0.015,-0.708,2.14E-3,-4.02,{"v":5.73e-05,"d":"5.73E-05"},0.00013,0.188,"+/-","RNA and DNA synthesis inhibitor","DNA","Conv.Chemo"]
["ACADM","Navitoclax",0.455,0.0222,-0.724,0.00152,-4.02,{"v":5.74e-05,"d":"5.74E-05"},0.000131,0.188,"+/-","Bcl-2,Bcl-XL inhibitor","BCL2;BCL2L2;BAD;BCL2L1;MCL1","Apoptotic modulator"]
["C1orf112","Hydroxyurea",0.676,0.000207,-0.527,0.0361,-4.02,{"v":5.75e-05,"d":"5.75E-05"},0.000131,0.188,"+/-","Antineoplastic agent","RRM1","Conv.Chemo"]
["BRPF1","GSK923295",-0.407,0.0435,0.75,0.000814,4.02,{"v":5.87e-05,"d":"5.87E-05"},0.000132,0.188,"-/+","CENP-E inhibitor","CENPE","Kinesin inhibitor"]
["ABI3","Fludarabine",-0.68,1.85E-4,0.52,0.0389,4.02,{"v":5.89e-05,"d":"5.89E-05"},1.34E-4,0.188,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["AP1B1","Tozasertib",-0.541,0.00527,0.663,0.0051,4.01,{"v":6.01e-05,"d":"6.01E-05"},1.34E-4,0.188,"-/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["BTG3","Danusertib",0.633,0.000691,-0.577,0.0193,-4.01,{"v":6.04e-05,"d":"6.04E-05"},1.35E-4,0.188,"+/-","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["ABRAXAS1","Agerafenib_CEP_32496",0.203,0.331,-0.833,{"v":6.2e-05,"d":"6.20E-05"},-4.01,{"v":6.04e-05,"d":"6.04E-05"},1.36E-4,0.188,"0/-","BRAF(V600E) inhibitor","BRAF;RAF1;KIT;RET;LCK;ABL1;PDGFRB;CSF1R;MET;EGFR;KDR;EPHA2","Kinase inhibitor"]
["ATL3","Cytarabine",-0.714,{"v":6.06e-05,"d":"6.06E-05"},0.468,0.0676,4.01,{"v":6.04e-05,"d":"6.04E-05"},1.36E-4,0.188,"-/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["C1QBP","Tivozanib",0.293,0.155,-0.801,1.93E-4,-4.01,{"v":6.07e-05,"d":"6.07E-05"},1.36E-4,0.188,"0/-","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["ADGRE5","Docetaxel",-0.496,0.0116,0.695,2.8E-3,4.01,{"v":6.1e-05,"d":"6.10E-05"},1.36E-4,0.188,"-/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["ASB9","Omacetaxine",-0.671,2.42E-4,0.53,0.0348,4.01,{"v":6.13e-05,"d":"6.13E-05"},1.36E-4,0.188,"-/+","Protein synthesis inhib (80 S ribosome)","RPL3","Conv.Chemo"]
["CARMIL2","Itraconazole",0.134,0.524,-0.853,{"v":2.67e-05,"d":"2.67E-05"},-4.01,{"v":6.15e-05,"d":"6.15E-05"},1.36E-4,0.188,"0/-","antifungal, hedgehog signaling inhibitor","CYP51A1;CYP3A4","Other"]
["APOM","PAC_1",-0.445,0.0259,0.728,1.4E-3,4.01,{"v":6.18e-05,"d":"6.18E-05"},1.37E-4,0.188,"-/+","procaspase-3 activator","CASP3","Apoptotic modulator"]
["ATG14","Selinexor",-0.569,2.99E-3,0.638,0.00785,4,{"v":6.24e-05,"d":"6.24E-05"},1.37E-4,0.188,"-/+","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["C8orf33","Filanesib",0.46,0.0208,-0.718,1.74E-3,-4,{"v":6.3E-5,"d":"6.30E-05"},0.000138,0.188,"+/-","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["ACAD11","Abemaciclib",-0.162,0.438,0.844,{"v":3.98e-05,"d":"3.98E-05"},4,{"v":6.44e-05,"d":"6.44E-05"},0.00014,0.188,"0/+","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["AK6","Raltitrexed",0.606,1.32E-3,-0.601,0.0138,-3.99,{"v":6.51e-05,"d":"6.51E-05"},0.000141,0.188,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["ANKS6","UNC0638",0.0579,0.783,-0.871,{"v":1.1E-5,"d":"1.10E-05"},-3.99,{"v":6.53e-05,"d":"6.53E-05"},0.000143,0.188,"0/-","G9a, GLP inhibitor","EHMT2","Differentiating.epigenetic modifier"]
["ASB7","Mitomycin_C",-0.0876,0.677,0.864,{"v":1.61e-05,"d":"1.61E-05"},3.99,{"v":6.56e-05,"d":"6.56E-05"},0.000143,0.188,"0/+","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["AURKB","Cytarabine.Idarubicin",0.716,{"v":5.77E-5,"d":"5.77E-05"},-0.46,0.073,-3.99,{"v":6.58E-5,"d":"6.58E-05"},1.44E-4,0.188,"+/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["ACSL4","Sitravatinib",0.788,{"v":2.95e-06,"d":"2.95E-06"},-0.318,0.23,-3.99,{"v":6.67e-05,"d":"6.67E-05"},1.44E-4,0.188,"+/0","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["ATXN2L","Lonafarnib",0.441,0.0272,-0.726,0.00144,-3.99,{"v":6.67e-05,"d":"6.67E-05"},1.44E-4,0.188,"+/-","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["BTD","BMS863233",-0.599,0.00155,0.606,0.0128,3.99,{"v":6.71e-05,"d":"6.71E-05"},1.44E-4,0.188,"-/+","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["ABCC10","Danusertib",-0.519,0.0078,0.674,0.00416,3.99,{"v":6.72e-05,"d":"6.72E-05"},1.45E-4,0.188,"-/+","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["APOE","Prexasertib",-0.874,{"v":1.11E-8,"d":"1.11E-08"},0.0425,0.876,3.98,{"v":6.77e-05,"d":"6.77E-05"},1.45E-4,0.188,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["AKIRIN1","BX_912",0.439,0.0281,-0.727,1.42E-3,-3.98,{"v":6.78e-05,"d":"6.78E-05"},1.46E-4,0.188,"+/-","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["ACAA2","Bleomycin",-0.519,0.00791,0.675,4.15E-3,3.98,{"v":6.79e-05,"d":"6.79E-05"},1.46E-4,0.188,"-/+","Glycopeptide antibiotic, causes DNA breaks","DNA","Conv.Chemo"]
["ASXL1","E7820",0.481,0.0148,-0.701,0.0025,-3.98,{"v":6.8e-05,"d":"6.80E-05"},1.46E-4,0.188,"+/-","Integrin alpha2 expression inhibitor","ITGA2","Other"]
["ADGRE5","Cytarabine",-0.748,{"v":1.72e-05,"d":"1.72E-05"},0.401,0.124,3.98,{"v":6.82e-05,"d":"6.82E-05"},1.46E-4,0.188,"-/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ACOT2","AR_42",-0.427,0.0335,0.734,0.00121,3.98,{"v":6.83e-05,"d":"6.83E-05"},1.46E-4,0.188,"-/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["BUB1","Cladribine",0.618,1E-3,-0.586,0.0171,-3.98,{"v":6.85e-05,"d":"6.85E-05"},1.47E-4,0.188,"+/-","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["CCDC136","AZD3965",0.0885,0.674,-0.863,{"v":1.71e-05,"d":"1.71E-05"},-3.98,{"v":6.89e-05,"d":"6.89E-05"},1.47E-4,0.188,"0/-","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["AKIRIN2","GSK_461364",0.433,0.0305,-0.73,1.34E-3,-3.98,{"v":6.95e-05,"d":"6.95E-05"},0.000148,0.188,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["C1QBP","Ponatinib",0.288,0.163,-0.799,0.000206,-3.98,{"v":6.97E-5,"d":"6.97E-05"},0.000149,0.188,"0/-","Broad TK inhibitor","ABL1;PDGFRA;KDR;FGFR1;SRC;KIT","Kinase inhibitor"]
["ABCC4","TGR_1202",0.354,0.0828,-0.771,0.000477,-3.98,{"v":6.97E-5,"d":"6.97E-05"},0.00015,0.188,"0/-","PI3Kdelta inhibitor","PIK3CD","Kinase inhibitor"]
["C10orf88","Niraparib",0.331,0.107,-0.781,0.000358,-3.98,{"v":7.03e-05,"d":"7.03E-05"},0.00015,0.188,"0/-","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["ATP5PD","Filanesib",-0.407,0.0433,0.743,0.000965,3.97,{"v":7.05e-05,"d":"7.05E-05"},0.000151,0.188,"-/+","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["BRCC3","Foretinib",0.407,0.0436,-0.744,9.59E-4,-3.97,{"v":7.06e-05,"d":"7.06E-05"},0.000151,0.188,"+/-","MET, VEGFR2 inhibitor","MET;KDR","Kinase inhibitor"]
["AGPAT3","Cerdulatinib",-0.528,6.62E-3,0.665,0.00491,3.97,{"v":7.06e-05,"d":"7.06E-05"},0.000151,0.188,"-/+","JAK, SYK inhibitor","JAK1;JAK2;JAK3;TYK2;SYK","Kinase inhibitor"]
["ANXA7","Sirolimus",-0.518,0.00801,0.673,0.00424,3.97,{"v":7.06e-05,"d":"7.06E-05"},0.000151,0.188,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["BUB1","Prexasertib",0.783,{"v":3.79e-06,"d":"3.79E-06"},-0.325,0.22,-3.97,{"v":7.18e-05,"d":"7.18E-05"},0.000151,0.188,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["CARNMT1","Sunitinib",0.387,0.056,-0.753,7.54E-4,-3.97,{"v":7.2e-05,"d":"7.20E-05"},0.000153,0.188,"0/-","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["ARHGAP18","CC_223",-0.428,0.0329,0.731,0.00129,3.97,{"v":7.22e-05,"d":"7.22E-05"},0.000153,0.188,"-/+","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["C1orf112","Carboplatin",0.573,0.00278,-0.626,0.00949,-3.96,{"v":7.43e-05,"d":"7.43E-05"},1.54E-4,0.188,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["AMER1","GSK_461364",0.689,0.000138,-0.491,0.0533,-3.96,{"v":7.58e-05,"d":"7.58E-05"},0.000157,0.188,"+/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["ABRACL","Pemetrexed",-0.726,{"v":4e-05,"d":"4.00E-05"},0.433,0.0936,3.96,{"v":7.6e-05,"d":"7.60E-05"},0.000158,0.188,"-/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["ADD3","GSK_1070916",-0.259,0.211,0.807,0.000157,3.96,{"v":7.6e-05,"d":"7.60E-05"},0.000159,0.188,"0/+","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["ACSF2","Raltitrexed",-0.706,{"v":8.12e-05,"d":"8.12E-05"},0.466,0.0687,3.96,{"v":7.62e-05,"d":"7.62E-05"},0.000159,0.188,"-/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["ADGRE5","Cabazitaxel",-0.66,0.000327,0.529,0.0351,3.95,{"v":7.75E-5,"d":"7.75E-05"},0.000159,0.188,"-/+","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["AP1B1","GSK_1070916",-0.48,0.015,0.695,0.00279,3.95,{"v":7.84e-05,"d":"7.84E-05"},0.000161,0.188,"-/+","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["ARPC1B","Cytarabine",-0.577,0.00252,0.619,0.0106,3.95,{"v":7.85e-05,"d":"7.85E-05"},1.63E-4,0.188,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ATXN7L2","Vistusertib",0.422,0.0356,-0.731,0.00129,-3.95,{"v":7.86E-5,"d":"7.86E-05"},1.63E-4,0.188,"+/-","mTOR inhibitor, ATP-competitive","MTOR","Kinase inhibitor"]
["BTBD10","Vinflunine",0.65,0.00044,-0.542,0.0302,-3.95,{"v":7.86E-5,"d":"7.86E-05"},1.63E-4,0.188,"+/-","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["CALHM2","8_amino_adenosine",-0.334,0.103,0.776,4.15E-4,3.95,{"v":7.87e-05,"d":"7.87E-05"},1.63E-4,0.188,"0/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["ACAP2","8_amino_adenosine",-0.494,0.0121,0.686,0.00337,3.95,{"v":7.89e-05,"d":"7.89E-05"},1.63E-4,0.188,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["BYSL","Pemetrexed",0.749,{"v":1.68e-05,"d":"1.68E-05"},-0.389,0.136,-3.95,{"v":7.93e-05,"d":"7.93E-05"},1.63E-4,0.188,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["AGO1","Cytarabine.Idarubicin",-0.526,0.00695,0.662,0.00522,3.95,{"v":7.95e-05,"d":"7.95E-05"},1.63E-4,0.188,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["CACYBP","8_amino_adenosine",0.442,0.0268,-0.718,1.72E-3,-3.94,{"v":8.03E-5,"d":"8.03E-05"},1.64E-4,0.188,"+/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["CAPG","Everolimus",-0.216,0.3,0.821,{"v":9.72e-05,"d":"9.72E-05"},3.94,{"v":8.08e-05,"d":"8.08E-05"},1.65E-4,0.188,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["APAF1","Topotecan",-0.546,0.00477,0.645,0.007,3.94,{"v":8.1e-05,"d":"8.10E-05"},1.66E-4,0.188,"-/+","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["BYSL","Raltitrexed",0.694,1.2E-4,-0.48,0.0599,-3.94,{"v":8.17e-05,"d":"8.17E-05"},1.66E-4,0.188,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["APLF","Bafetinib",0.508,0.0096,-0.674,0.00418,-3.94,{"v":8.19e-05,"d":"8.19E-05"},0.000168,0.188,"+/-","ABL, Lyn inhibitor","ABL1;LYN","Kinase inhibitor"]
["BUB1","Pemetrexed",0.712,{"v":6.5e-05,"d":"6.50E-05"},-0.451,0.0796,-3.94,{"v":8.22e-05,"d":"8.22E-05"},0.000168,0.188,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["APOBR","Erastin",-0.402,0.0464,0.74,0.00104,3.94,{"v":8.23e-05,"d":"8.23E-05"},0.000168,0.188,"-/+","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["CCDC167","Etoposide",0.78,{"v":4.19e-06,"d":"4.19E-06"},-0.319,0.228,-3.94,{"v":8.23e-05,"d":"8.23E-05"},0.000168,0.188,"+/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["BEND3","A_1155463",-0.477,0.016,0.695,0.00279,3.94,{"v":8.3e-05,"d":"8.30E-05"},0.000168,0.188,"-/+","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2","Apoptotic modulator"]
["ANXA7","Palbociclib",-0.675,2.14E-4,0.505,0.0458,3.94,{"v":8.32e-05,"d":"8.32E-05"},0.00017,0.188,"-/+","Topoisomerase I inhibitor, Camptothecin analog","CDK4;CDK6","Kinase inhibitor"]
["CAPG","Pemetrexed",-0.489,0.0131,0.687,3.29E-3,3.94,{"v":8.32e-05,"d":"8.32E-05"},0.00017,0.188,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["BUB1","Gemcitabine",0.667,0.000273,-0.516,0.0407,-3.93,{"v":8.38e-05,"d":"8.38E-05"},0.00017,0.188,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["ATXN7L3B","Everolimus",0.445,0.026,-0.715,0.00184,-3.93,{"v":8.39e-05,"d":"8.39E-05"},0.000171,0.188,"+/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["BAZ2A","Daporinad",0.766,{"v":8.17e-06,"d":"8.17E-06"},-0.35,0.184,-3.93,{"v":8.45e-05,"d":"8.45E-05"},0.000172,0.188,"+/0","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["APLF","Nilotinib",0.493,0.0124,-0.683,0.00353,-3.93,{"v":8.5e-05,"d":"8.50E-05"},0.000172,0.188,"+/-","ABL inhibitor","ABL1;KIT","Kinase inhibitor"]
["CBR3","Dovitinib",-0.3,0.145,0.787,0.000294,3.93,{"v":8.53E-5,"d":"8.53E-05"},1.73E-4,0.188,"0/+","FGFR inhibitor","FGFR1;FGFR3;KIT;FLT3;FLT4","Kinase inhibitor"]
["AC091230.1","Danusertib",-0.427,0.0333,0.725,1.49E-3,3.93,{"v":8.57e-05,"d":"8.57E-05"},1.73E-4,0.188,"-/+","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["AKR1A1","Niraparib",-0.529,0.00654,0.655,0.00589,3.92,{"v":8.7e-05,"d":"8.70E-05"},1.74E-4,0.188,"-/+","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["BACH2","Cisplatin",-0.149,0.478,0.84,{"v":4.59e-05,"d":"4.59E-05"},3.92,{"v":8.74e-05,"d":"8.74E-05"},1.75E-4,0.188,"0/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["CCDC138","Cytarabine.Idarubicin",0.631,0.000725,-0.557,0.0249,-3.92,{"v":8.84e-05,"d":"8.84E-05"},1.76E-4,0.188,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["ATG16L2","UCN_01",-0.55,0.00443,0.637,0.00793,3.92,{"v":8.86e-05,"d":"8.86E-05"},0.000179,0.188,"-/+","PKCbeta, PDK1, Chk, Cdk2 inhibitor","PRKCB;PDPK1","Kinase inhibitor"]
["C1orf112","Cytarabine.Idarubicin",0.738,{"v":2.58E-5,"d":"2.58E-05"},-0.401,0.123,-3.92,{"v":8.94e-05,"d":"8.94E-05"},0.000179,0.188,"+/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["CASP1","TGR_1202",-0.13,0.536,0.845,{"v":3.73e-05,"d":"3.73E-05"},3.92,{"v":8.95e-05,"d":"8.95E-05"},0.000179,0.188,"0/+","PI3Kdelta inhibitor","PIK3CD","Kinase inhibitor"]
["ADIPOR2","Pracinostat",-0.303,0.14,0.784,3.21E-4,3.92,{"v":8.99e-05,"d":"8.99E-05"},0.000179,0.188,"0/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["ARID3B","VER_155008",-0.159,0.447,0.837,{"v":5.37e-05,"d":"5.37E-05"},3.92,{"v":8.99e-05,"d":"8.99E-05"},0.000179,0.188,"0/+","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["BRPF1","ENMD_2076",-0.647,0.000472,0.537,0.032,3.92,{"v":9.01e-05,"d":"9.01E-05"},0.000179,0.188,"-/+","pan-Aurora, VEGFR inhibitor","AURKA;FLT3;RET;FLT4;SRC;CSF1R;NTRK1;PDGFRA;BLK;KDR;YES1;FYN;AURKB;PTK2;FGFR2;FGFR1;JAK2;KIT;ABL1","Kinase inhibitor"]
["CCDC117","Tozasertib",0.0306,0.885,-0.871,{"v":1.11E-5,"d":"1.11E-05"},-3.91,{"v":9.15e-05,"d":"9.15E-05"},0.000179,0.188,"0/-","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["AASDHPPT","Dovitinib",0.447,0.0251,-0.71,0.00205,-3.91,{"v":9.16e-05,"d":"9.16E-05"},1.83E-4,0.188,"+/-","FGFR inhibitor","FGFR1;FGFR3;KIT;FLT3;FLT4","Kinase inhibitor"]
["ABI3","Prexasertib",-0.611,1.17E-3,0.577,0.0194,3.91,{"v":9.17e-05,"d":"9.17E-05"},1.83E-4,0.188,"-/+","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["AP3D1","Topotecan",-0.426,0.0338,0.723,1.57E-3,3.91,{"v":9.23e-05,"d":"9.23E-05"},1.83E-4,0.188,"-/+","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["ACSF2","Pemetrexed",-0.682,0.000171,0.489,0.0548,3.91,{"v":9.23e-05,"d":"9.23E-05"},1.84E-4,0.188,"-/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["ARF4","Mitomycin_C",0.2,0.337,-0.822,{"v":9.18e-05,"d":"9.18E-05"},-3.91,{"v":9.25e-05,"d":"9.25E-05"},1.84E-4,0.188,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["CCDC138","8_amino_adenosine",0.612,1.14E-3,-0.575,0.0198,-3.91,{"v":9.25e-05,"d":"9.25E-05"},1.84E-4,0.188,"+/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["BNIP3","KU_60019",0.373,0.0663,-0.751,0.000804,-3.91,{"v":9.35e-05,"d":"9.35E-05"},1.84E-4,0.188,"0/-","ATM inhibitor","ATM","Kinase inhibitor"]
["C1orf112","Etoposide",0.63,0.00073,-0.554,0.0259,-3.91,{"v":9.36e-05,"d":"9.36E-05"},1.85E-4,0.188,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["AC004151.1","Ivosidenib",-0.0746,0.723,0.86,{"v":1.97e-05,"d":"1.97E-05"},3.91,{"v":9.37e-05,"d":"9.37E-05"},1.85E-4,0.188,"0/+","IDH1 R132H and R132C inhibitor","IDH1","Differentiating.epigenetic modifier"]
["BUB1","Aldoxorubicin",0.466,0.0188,-0.697,0.00272,-3.91,{"v":9.42e-05,"d":"9.42E-05"},1.85E-4,0.188,"+/-","Topoisomerase II inhibitor, Albumin binding","TOP2A;TOP2B","Conv.Chemo"]
["C1orf52","Uprosertib",0.499,0.0112,-0.674,0.0042,-3.9,{"v":9.49e-05,"d":"9.49E-05"},0.000186,0.188,"+/-","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["CASP1","GSK2256098",-0.305,0.138,0.782,0.000345,3.9,{"v":9.51e-05,"d":"9.51E-05"},0.000186,0.188,"0/+","FAK inhibitor","PTK2","Kinase inhibitor"]
["APAF1","Cladribine",-0.41,0.0418,0.73,1.31E-3,3.9,{"v":9.51e-05,"d":"9.51E-05"},0.000186,0.188,"-/+","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["ARHGAP23","Cytarabine",0.441,0.0273,-0.712,1.97E-3,-3.9,{"v":9.52e-05,"d":"9.52E-05"},0.000186,0.188,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["AP3D1","Cytarabine.Idarubicin",-0.464,0.0196,0.698,2.66E-3,3.9,{"v":9.6e-05,"d":"9.60E-05"},0.000186,0.188,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["BSCL2","PD0325901",-0.621,0.000914,0.563,0.0232,3.9,{"v":9.6e-05,"d":"9.60E-05"},0.000187,0.188,"-/+","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["ATM","Midostaurin",-0.2,0.339,0.822,{"v":9.49e-05,"d":"9.49E-05"},3.9,{"v":9.65e-05,"d":"9.65E-05"},0.000187,0.188,"0/+","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["ALDH7A1","AZD3965",-0.371,0.0677,0.75,8.12E-4,3.9,{"v":9.69e-05,"d":"9.69E-05"},0.000187,0.188,"0/+","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["BEND3","WEHI_539",-0.451,0.0236,0.705,0.00228,3.9,{"v":9.7E-5,"d":"9.70E-05"},0.000189,0.188,"-/+","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["BCHE","Pevonedistat",0.494,0.012,-0.676,0.00408,-3.89,{"v":9.83e-05,"d":"9.83E-05"},0.000189,0.188,"+/-","NAE inhibitor","NAE1","Metabolic modifier"]
["AGO1","Raltitrexed",-0.746,{"v":1.89e-05,"d":"1.89E-05"},0.379,0.147,3.89,{"v":9.84e-05,"d":"9.84E-05"},0.00019,0.188,"-/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["AURKB","Gemcitabine",0.706,{"v":8.06e-05,"d":"8.06E-05"},-0.449,0.0814,-3.89,{"v":9.89e-05,"d":"9.89E-05"},0.00019,0.188,"+/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["ATIC","Cytarabine",0.572,0.00279,-0.611,0.0119,-3.89,{"v":9.92e-05,"d":"9.92E-05"},0.00019,0.188,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ARHGAP42","Resminostat",0.69,1.34E-4,-0.472,0.0648,-3.89,{"v":9.97e-05,"d":"9.97E-05"},0.00019,0.188,"+/0","HDAC1, 3, 6 inhibitor","HDAC1;HDAC3;HDAC6","Differentiating.epigenetic modifier"]
["ARHGAP18","Everolimus",-0.309,0.133,0.779,3.79E-4,3.89,{"v":9.99e-05,"d":"9.99E-05"},0.000191,0.188,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["BRCA2","Prexasertib",0.839,{"v":1.66E-7,"d":"1.66E-07"},-0.144,0.596,-3.89,{"v":1E-4,"d":"1.00E-04"},0.000191,0.188,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["BABAM2","Agerafenib_CEP_32496",0.288,0.162,-0.787,0.000296,-3.89,{"v":1E-4,"d":"1.00E-04"},1.92E-4,0.188,"0/-","BRAF(V600E) inhibitor","BRAF;RAF1;KIT;RET;LCK;ABL1;PDGFRB;CSF1R;MET;EGFR;KDR;EPHA2","Kinase inhibitor"]
["CAPN1","VER_155008",-0.346,0.0903,0.762,0.000609,3.89,{"v":1E-4,"d":"1.00E-04"},1.92E-4,0.188,"0/+","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["APLF","TAK_530",0.455,0.0221,-0.701,2.49E-3,-3.89,1.01E-4,1.92E-4,0.188,"+/-","Pan-HER inhibitor","EGFR;ERBB2;ERBB3","Kinase inhibitor"]
["C1orf112","Cytarabine",0.751,{"v":1.51e-05,"d":"1.51E-05"},-0.367,0.163,-3.89,1.01E-4,1.92E-4,0.188,"+/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["BUD31","BMS863233",0.353,0.0835,-0.758,0.000672,-3.89,1.01E-4,1.93E-4,0.188,"0/-","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["CBR1","GSK_1070916",-0.835,{"v":2.04E-7,"d":"2.04E-07"},0.153,0.572,3.89,1.02E-4,1.93E-4,0.188,"-/0","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["BRAT1","BIIB021",0.58,0.00236,-0.602,0.0136,-3.89,1.02E-4,1.94E-4,0.188,"+/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["AKIRIN1","Pemetrexed",0.697,0.000109,-0.461,0.0723,-3.89,1.02E-4,1.94E-4,0.188,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["AKT1","Carfilzomib",-0.231,0.267,0.809,1.47E-4,3.89,1.02E-4,1.94E-4,0.188,"0/+","Proteasome inhibitor (20S subunit)","PSMB5;PSMB8;PSMB1;PSMB2;PSMB9;PSMB10","Protease.proteasome inhibitor"]
["CARHSP1","Disulfiram_CuCl2",0.377,0.0635,-0.745,0.000929,-3.88,0.000104,1.94E-4,0.188,"0/-","alcohol dehydrogenase inhibitor","ALDH1A1","Metabolic modifier"]
["BRPF1","Rigosertib",-0.537,5.62E-3,0.639,0.00766,3.88,0.000104,0.000196,0.189,"-/+","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["ABRAXAS2","Foretinib",0.284,0.169,-0.788,0.000291,-3.88,1.05E-4,0.000196,0.189,"0/-","MET, VEGFR2 inhibitor","MET;KDR","Kinase inhibitor"]
["C10orf88","8_amino_adenosine",0.433,0.0305,-0.713,0.00194,-3.88,1.05E-4,0.000197,0.189,"+/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["ADGRE5","RGFP966",-0.636,0.000636,0.541,0.0306,3.88,1.06E-4,0.000198,0.189,"-/+","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["ABRAXAS1","Merestinib",0.271,0.19,-0.793,0.000251,-3.88,1.06E-4,0.000198,0.189,"0/-","MET inhibitor","MET","Kinase inhibitor"]
["ATP9B","Auranofin",-0.22,0.29,0.812,1.35E-4,3.88,1.06E-4,0.000198,0.189,"0/+","Antirheumatic agent","PRDX5;IKBKB","Conv.Chemo"]
["ARFGEF1","AMG319",0.571,0.0029,-0.609,0.0124,-3.87,1.07E-4,0.000199,0.189,"+/-","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["ARHGAP1","Cytarabine",-0.667,0.000273,0.5,0.0483,3.87,1.08E-4,0.000201,0.189,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ARHGAP17","Losmapimod",-0.0448,0.831,0.864,{"v":1.58e-05,"d":"1.58E-05"},3.87,1.08E-4,2.02E-4,0.189,"0/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["AC091230.1","AT9283",-0.278,0.178,0.789,0.00028,3.87,1.08E-4,2.02E-4,0.189,"0/+","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["AKIRIN2","Eribulin",0.27,0.192,-0.792,0.000255,-3.87,0.000109,2.02E-4,0.189,"0/-","Mitotic inhibitor, microtubule depolymerizer","TUBB1","Conv.Chemo"]
["ARL8A","Navitoclax",0.525,0.00701,-0.647,0.00675,-3.87,0.000109,2.03E-4,0.189,"+/-","Bcl-2,Bcl-XL inhibitor","BCL2;BCL2L2;BAD;BCL2L1;MCL1","Apoptotic modulator"]
["BRCA2","Cytarabine",0.739,{"v":2.49e-05,"d":"2.49E-05"},-0.385,0.141,-3.87,0.000109,2.03E-4,0.189,"+/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["C10orf88","Idarubicin",0.592,0.00184,-0.587,0.0169,-3.87,1.1E-4,2.03E-4,0.189,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["APAF1","Cytarabine.Idarubicin",-0.692,1.27E-4,0.463,0.0711,3.87,1.1E-4,2.05E-4,0.189,"-/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["BUB1","RGFP966",0.764,{"v":8.93e-06,"d":"8.93E-06"},-0.334,0.206,-3.87,1.11E-4,2.05E-4,0.189,"+/0","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["ATRNL1","SB743921",0.435,0.0299,-0.71,0.00208,-3.86,1.11E-4,2.05E-4,0.189,"+/-","Mitotic inhibitor, Eg5, KSP inhibitor","KIF11","Kinesin inhibitor"]
["CHD1","VER_155008",0.496,0.0116,-0.798,0.00021,-4.68,{"v":2.83E-6,"d":"2.83E-06"},{"v":1.99e-05,"d":"1.99E-05"},0.189,"+/-","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["DNA2","Prexasertib",0.745,{"v":1.92e-05,"d":"1.92E-05"},-0.587,0.0167,-4.68,{"v":2.93e-06,"d":"2.93E-06"},{"v":2.04e-05,"d":"2.04E-05"},0.189,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["SNX22","Abexinostat",0.574,0.00269,-0.728,1.39E-3,-4.51,{"v":6.45e-06,"d":"6.45E-06"},{"v":3.02e-05,"d":"3.02E-05"},0.189,"+/-","HDAC1 selective inhibitor","HDAC1","Differentiating.epigenetic modifier"]
["SPAG5","Clofarabine",0.617,0.00102,-0.694,0.00285,-4.51,{"v":6.6e-06,"d":"6.60E-06"},{"v":3.07e-05,"d":"3.07E-05"},0.189,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["BRPF1","ABT_751",-0.591,0.00188,0.587,0.0169,3.86,1.12E-4,0.000206,0.19,"-/+","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["ASXL1","Litronesib",0.505,0.01,-0.661,0.00527,-3.86,1.12E-4,0.000207,0.19,"+/-","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["CCDC138","Alisertib",0.489,0.0132,-0.673,0.00426,-3.86,1.12E-4,0.000208,0.19,"+/-","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["ANKRD50","Vorinostat",0.602,0.00144,-0.574,0.02,-3.86,1.13E-4,0.000208,0.19,"+/-","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["APBB2","Carfilzomib",0.312,0.129,-0.773,4.44E-4,-3.86,1.13E-4,0.000208,0.19,"0/-","Proteasome inhibitor (20S subunit)","PSMB5;PSMB8;PSMB1;PSMB2;PSMB9;PSMB10","Protease.proteasome inhibitor"]
["ASXL1","Filanesib",0.429,0.0324,-0.712,1.98E-3,-3.86,0.000114,0.000209,0.19,"+/-","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["DDX5","Prexasertib",0.813,{"v":8e-07,"d":"8.00E-07"},-0.456,0.0759,-4.65,{"v":3.3e-06,"d":"3.30E-06"},{"v":2.22e-05,"d":"2.22E-05"},0.19,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["CKB","Tacrolimus",-0.295,0.153,0.868,{"v":1.34E-5,"d":"1.34E-05"},4.65,{"v":3.31e-06,"d":"3.31E-06"},{"v":2.22e-05,"d":"2.22E-05"},0.19,"0/+","binds FKBP12, causes inhibition of calcineurin","FKBP1A","Rapalog"]
["CDC25C","Gemcitabine",0.577,0.00252,-0.748,0.00087,-4.65,{"v":3.36E-6,"d":"3.36E-06"},{"v":2.22e-05,"d":"2.22E-05"},0.19,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["FIP1L1","Eltanexor",0.579,0.00245,-0.732,0.00126,-4.56,{"v":5.24e-06,"d":"5.24E-06"},{"v":2.59e-05,"d":"2.59E-05"},0.19,"+/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["GRN","Prexasertib",-0.703,{"v":8.92E-5,"d":"8.92E-05"},0.617,0.0109,4.55,{"v":5.24e-06,"d":"5.24E-06"},{"v":2.59e-05,"d":"2.59E-05"},0.19,"-/+","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["FMR1","IOX_2",0.0971,0.644,-0.904,{"v":1.58e-06,"d":"1.58E-06"},-4.55,{"v":5.48E-6,"d":"5.48E-06"},{"v":2.62E-5,"d":"2.62E-05"},0.19,"0/-","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["GNPDA1","A_1210477",0.59,1.89E-3,-0.72,1.65E-3,-4.54,{"v":5.74e-06,"d":"5.74E-06"},{"v":2.69E-5,"d":"2.69E-05"},0.19,"+/-","MCL-1 inhibitor","MCL1","Apoptotic modulator"]
["FIGNL1","PCI_34051",0.389,0.0543,-0.825,{"v":8.3e-05,"d":"8.30E-05"},-4.53,{"v":5.95e-06,"d":"5.95E-06"},{"v":2.74e-05,"d":"2.74E-05"},0.19,"0/-","HDAC8 inhibitor","HDAC8","Differentiating.epigenetic modifier"]
["GLB1","Prexasertib",-0.754,{"v":1.37e-05,"d":"1.37E-05"},0.538,0.0316,4.52,{"v":6.07e-06,"d":"6.07E-06"},{"v":2.82e-05,"d":"2.82E-05"},0.19,"-/+","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["FOXP1","Exemestane",0.391,0.0534,-0.822,{"v":9.4e-05,"d":"9.40E-05"},-4.5,{"v":6.7e-06,"d":"6.70E-06"},{"v":3.02e-05,"d":"3.02E-05"},0.19,"0/-","Aromatase inhibitor","CYP19A1","Hormone therapy"]
["GRK5","Acitretin",0.495,0.0118,-0.774,0.000436,-4.5,{"v":6.92e-06,"d":"6.92E-06"},{"v":3.04E-5,"d":"3.04E-05"},0.19,"+/-","Retinoic acid receptor agonist","RARA;RARB;RXRA;RXRB;RXRG","Differentiating.epigenetic modifier"]
["GNL2","VER_155008",0.624,0.000859,-0.686,3.32E-3,-4.5,{"v":6.96e-06,"d":"6.96E-06"},{"v":3.07e-05,"d":"3.07E-05"},0.19,"+/-","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["GMNN","Raltitrexed",0.731,{"v":3.27e-05,"d":"3.27E-05"},-0.565,0.0227,-4.49,{"v":7.05e-06,"d":"7.05E-06"},{"v":3.09e-05,"d":"3.09E-05"},0.19,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["FOXP1","Enzalutamide",0.466,0.0188,-0.787,0.000297,-4.49,{"v":7.29e-06,"d":"7.29E-06"},{"v":3.12e-05,"d":"3.12E-05"},0.19,"+/-","AR antagonist","AR","Hormone therapy"]
["FEN1","Cabazitaxel",-0.266,0.199,0.861,{"v":1.87e-05,"d":"1.87E-05"},4.48,{"v":7.33e-06,"d":"7.33E-06"},{"v":3.14e-05,"d":"3.14E-05"},0.19,"0/+","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["NSRP1","GSK_461364",0.49,0.0129,-0.84,{"v":4.57E-5,"d":"4.57E-05"},-5.03,{"v":4.96e-07,"d":"4.96E-07"},{"v":7.48e-06,"d":"7.48E-06"},0.19,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["MTMR14","Cytarabine",-0.685,0.00016,0.725,1.48E-3,5.02,{"v":5.15e-07,"d":"5.15E-07"},{"v":7.48e-06,"d":"7.48E-06"},0.19,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["VAMP5","Perifosine",0.0132,0.95,-0.915,{"v":6.92E-7,"d":"6.92E-07"},-4.49,{"v":7.2e-06,"d":"7.20E-06"},{"v":2.17e-05,"d":"2.17E-05"},0.19,"0/-","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["VPS51","Fulvestrant",0.187,0.372,-0.88,{"v":6.95e-06,"d":"6.95E-06"},-4.47,{"v":7.72e-06,"d":"7.72E-06"},{"v":2.3E-5,"d":"2.30E-05"},0.19,"0/-","Estrogen receptor antagonist","ESR1","Hormone therapy"]
["WASHC5","Raltitrexed",-0.533,0.00608,0.748,0.000863,4.47,{"v":7.93e-06,"d":"7.93E-06"},{"v":2.37E-5,"d":"2.37E-05"},0.19,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["TXNDC9","Gemcitabine",0.687,0.000148,-0.615,0.0112,-4.46,{"v":8.18e-06,"d":"8.18E-06"},{"v":2.5e-05,"d":"2.50E-05"},0.19,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["TXNDC9","Clofarabine",0.585,0.00213,-0.711,0.00203,-4.46,{"v":8.35e-06,"d":"8.35E-06"},{"v":2.55E-5,"d":"2.55E-05"},0.19,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["WDR37","Pemetrexed",-0.624,0.000865,0.679,0.00384,4.45,{"v":8.45e-06,"d":"8.45E-06"},{"v":2.55E-5,"d":"2.55E-05"},0.19,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["TTC1","TAK_901",0.496,0.0117,-0.767,0.000519,-4.45,{"v":8.47e-06,"d":"8.47E-06"},{"v":2.55E-5,"d":"2.55E-05"},0.19,"+/-","Aurora, Src family, JAK3, RTK inhibitor","AURKA;AURKB;JAK3;SRC;CLK2;FGR;LRRK2;YES1;LCK;FYN;ABL1;AXL;ABL2;HCK;RET;FRK;NTRK1;FGFR2","Kinase inhibitor"]
["ZNF77","Imiquimod",-0.068,0.747,-0.925,{"v":2.85e-07,"d":"2.85E-07"},-4.45,{"v":8.6e-06,"d":"8.60E-06"},{"v":2.62E-5,"d":"2.62E-05"},0.19,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["TXNDC9","Cisplatin",0.722,{"v":4.6E-5,"d":"4.60E-05"},-0.568,0.0217,-4.45,{"v":8.63e-06,"d":"8.63E-06"},{"v":2.62E-5,"d":"2.62E-05"},0.19,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["TPX2","Carboplatin",0.683,0.000169,-0.618,0.0108,-4.45,{"v":8.73e-06,"d":"8.73E-06"},{"v":2.67e-05,"d":"2.67E-05"},0.19,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["ZNF101","Eribulin",0.537,0.0056,-0.742,1E-3,-4.44,{"v":8.8e-06,"d":"8.80E-06"},{"v":2.7e-05,"d":"2.70E-05"},0.19,"+/-","Mitotic inhibitor, microtubule depolymerizer","TUBB1","Conv.Chemo"]
["ABRAXAS1","Tivozanib",0.0638,0.762,-0.858,{"v":2.15e-05,"d":"2.15E-05"},-3.86,1.15E-4,0.000211,0.191,"0/-","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["ABCD4","Tozasertib",-0.504,0.0101,0.66,0.00539,3.85,1.16E-4,2.12E-4,0.191,"-/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["ATXN2L","MK_8745",0.286,0.166,-0.783,0.000332,-3.85,1.17E-4,2.14E-4,0.191,"0/-","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["AP3S1","Carboplatin",-0.572,2.81E-3,0.603,0.0135,3.85,1.17E-4,2.14E-4,0.191,"-/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["C9orf78","Mocetinostat",0.383,0.0587,-0.737,1.14E-3,-3.85,1.18E-4,2.14E-4,0.191,"0/-","HDAC inhibitor (HDAC1 and 2-selective)","HDAC1;HDAC2;HDAC3;HDAC11","Differentiating.epigenetic modifier"]
["BIRC5","Cytarabine",0.637,0.000623,-0.533,0.0336,-3.85,1.18E-4,0.000216,0.191,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["CCDC174","Exemestane",0.463,0.0197,-0.688,0.00319,-3.85,0.000119,0.000216,0.191,"+/-","Aromatase inhibitor","CYP19A1","Hormone therapy"]
["BUB1","Olaparib",0.456,0.0219,-0.693,0.00293,-3.85,1.2E-4,0.000217,0.191,"+/-","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["AASDHPPT","Tamatinib",0.63,0.000746,-0.541,0.0306,-3.85,1.2E-4,0.000218,0.191,"+/-","SYK inhibitor","SYK","Kinase inhibitor"]
["ACO2","Ibrutinib",-0.201,0.334,0.815,1.2E-4,3.85,1.2E-4,0.000218,0.191,"0/+","BTK inhibitor","BTK;BLK;EGFR;FYN;LYN;LCK;BRAF;WNK1","Kinase inhibitor"]
["ANKRD63","Glasdegib",0.0916,0.663,-0.849,{"v":3.15E-5,"d":"3.15E-05"},-3.85,1.2E-4,0.000218,0.191,"0/-","Smo inhibitor","SMO","Hedgehog inhibitor"]
["BCL7A","Triapine",0.614,0.0011,-0.558,0.0247,-3.85,1.2E-4,0.000219,0.191,"+/-","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["C10orf88","Selinexor",0.503,0.0104,-0.66,0.00543,-3.85,1.2E-4,0.000219,0.191,"+/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["ARID5B","Vismodegib",0.241,0.245,-0.8,0.000198,-3.84,1.21E-4,0.000219,0.191,"0/-","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["ATP2B4","Pemetrexed",-0.551,0.00434,0.62,0.0104,3.84,1.22E-4,0.000219,0.191,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["ARID5B","Finasteride",0.202,0.333,-0.814,0.000123,-3.84,1.22E-4,0.000221,0.191,"0/-","type II 5-alpha reductase inhibitor","SRD5A2","Hormone therapy"]
["ARL8B","Prexasertib",-0.713,{"v":6.25e-05,"d":"6.25E-05"},0.422,0.104,3.84,1.22E-4,0.000221,0.191,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["AC093323.1","Paclitaxel",0.503,0.0104,-0.659,0.00551,-3.84,1.22E-4,0.000221,0.191,"+/-","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["ARHGAP23","Valrubicin",0.196,0.347,-0.816,1.16E-4,-3.84,0.000123,0.000221,0.191,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["ATP5PO","Alisertib",-0.466,0.019,0.685,0.0034,3.84,0.000123,2.22E-4,0.191,"-/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["C10orf88","SAR405838",0.547,0.00466,-0.622,0.0101,-3.84,1.25E-4,2.23E-4,0.191,"+/-","MDM2 inhibitor","MDM2;TP53","Apoptotic modulator"]
["CASC3","Filanesib",0.549,0.00448,-0.62,0.0105,-3.83,1.26E-4,0.000225,0.191,"+/-","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["AURKB","SN_38",0.664,2.92E-4,-0.493,0.0523,-3.83,1.27E-4,0.000226,0.191,"+/0","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["BLOC1S4","Indibulin",-0.633,0.000679,0.533,0.0336,3.83,1.27E-4,0.000227,0.191,"-/+","Mitoric inhibitor, Microtubule depolymerizer","TUBB","Conv.Chemo"]
["ARL8A","WEHI_539",0.713,{"v":6.28e-05,"d":"6.28E-05"},-0.419,0.106,-3.83,1.27E-4,0.000227,0.191,"+/0","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["CAD","Doramapimod",0.323,0.115,-0.764,0.000575,-3.83,0.000128,0.000228,0.191,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["AHNAK","Erlotinib",-0.214,0.305,0.808,0.000151,3.83,0.000129,0.00023,0.191,"0/+","EGFR inhibitor","EGFR","Kinase inhibitor"]
["ADGRE5","Alisertib",-0.596,1.65E-3,0.573,0.0204,3.83,0.000129,0.00023,0.191,"-/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["ACOT2","Tubastatin_A",-0.237,0.253,0.8,0.000201,3.83,0.000129,0.00023,0.191,"0/+","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["CBFA2T2","Selinexor",0.145,0.489,-0.831,{"v":6.55e-05,"d":"6.55E-05"},-3.83,0.000129,0.00023,0.191,"0/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["ACP2","PD0325901",-0.514,8.6E-3,0.648,0.00669,3.83,0.000129,2.31E-4,0.191,"-/+","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["C5orf34","Cytarabine",0.694,0.000119,-0.449,0.0812,-3.83,0.000129,2.31E-4,0.191,"+/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ABI3","Cisplatin",-0.519,0.00789,0.643,0.00717,3.83,0.00013,2.32E-4,0.191,"-/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["AASDHPPT","Glesatinib",0.576,0.00259,-0.593,0.0155,-3.83,0.00013,2.32E-4,0.191,"+/-","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["ABRACL","Topotecan",-0.47,0.0176,0.679,3.8E-3,3.83,0.00013,2.33E-4,0.191,"-/+","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["ADGRE5","Ridaforolimus",-0.465,0.0192,0.683,0.00354,3.83,0.00013,2.33E-4,0.191,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ADGRE5","Cytarabine.Idarubicin",-0.69,1.37E-4,0.455,0.0766,3.83,0.000131,2.34E-4,0.191,"-/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["ARPC2","Cytarabine",-0.402,0.0461,0.722,0.00159,3.82,0.000131,2.34E-4,0.191,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["APLF","Imatinib",0.503,0.0104,-0.655,0.00584,-3.82,0.000131,2.34E-4,0.191,"+/-","ABL, Kit, PDGFRB inhibitor","ABL1","Kinase inhibitor"]
["C1orf112","Vinorelbine",0.687,0.000149,-0.459,0.0738,-3.82,0.000131,2.34E-4,0.191,"+/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["BTG3","AZD6738",0.638,{"v":0.0006,"d":"6.00E-04"},-0.525,0.0369,-3.82,0.000132,0.000235,0.191,"+/-","ATR inihibitor","ATR","Kinase inhibitor"]
["BTBD10","Givinostat",0.311,0.13,-0.768,0.000509,-3.82,0.000132,0.000235,0.191,"0/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC10","Differentiating.epigenetic modifier"]
["ASB6","GSK_461364",0.538,0.00556,-0.627,0.00936,-3.82,0.000132,0.000235,0.191,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["ATP13A1","RGFP966",-0.597,0.00161,0.57,0.0211,3.82,0.000133,0.000235,0.191,"-/+","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["CALD1","Tirabrutinib",0.398,0.0485,-0.724,0.00153,-3.82,0.000133,0.000236,0.191,"+/-","BTK inhibitor","BTK","Kinase inhibitor"]
["APBA3","Tubastatin_A",-0.49,0.0129,0.664,0.00503,3.82,1.34E-4,0.000236,0.191,"-/+","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["KLHL12","Prexasertib",0.652,0.000412,-0.67,0.00453,-4.54,{"v":5.53e-06,"d":"5.53E-06"},{"v":2.29e-05,"d":"2.29E-05"},0.191,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["IDH3B","Foretinib",0.588,2E-3,-0.723,1.56E-3,-4.54,{"v":5.65e-06,"d":"5.65E-06"},{"v":2.37E-5,"d":"2.37E-05"},0.191,"+/-","MET, VEGFR2 inhibitor","MET;KDR","Kinase inhibitor"]
["LAT2","Palbociclib",-0.623,0.000875,0.694,0.00286,4.53,{"v":5.81e-06,"d":"5.81E-06"},{"v":2.47e-05,"d":"2.47E-05"},0.191,"-/+","Topoisomerase I inhibitor, Camptothecin analog","CDK4;CDK6","Kinase inhibitor"]
["MICU2","Sirolimus",-0.381,0.0601,0.829,{"v":7.33e-05,"d":"7.33E-05"},4.53,{"v":5.88e-06,"d":"5.88E-06"},{"v":2.49e-05,"d":"2.49E-05"},0.191,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["MIS18A","Cytarabine",0.634,0.000672,-0.684,3.47E-3,-4.53,{"v":5.93E-6,"d":"5.93E-06"},{"v":2.52e-05,"d":"2.52E-05"},0.191,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["KLHL26","Imiquimod",-0.0412,0.845,-0.925,{"v":2.84E-7,"d":"2.84E-07"},-4.53,{"v":5.98e-06,"d":"5.98E-06"},{"v":2.59e-05,"d":"2.59E-05"},0.191,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["IDH3A","Sunitinib",0.65,0.000442,-0.669,0.00461,-4.53,{"v":6.03e-06,"d":"6.03E-06"},{"v":2.62E-5,"d":"2.62E-05"},0.191,"+/-","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["KNSTRN","Clofarabine",0.592,0.00184,-0.718,1.75E-3,-4.52,{"v":6.07e-06,"d":"6.07E-06"},{"v":2.62E-5,"d":"2.62E-05"},0.191,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["MAP9","AMG319",0.0815,0.698,-0.905,{"v":1.44E-6,"d":"1.44E-06"},-4.52,{"v":6.16e-06,"d":"6.16E-06"},{"v":2.64e-05,"d":"2.64E-05"},0.191,"0/-","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["ASRGL1","Tirabrutinib",0.257,0.215,-0.791,0.000267,-3.82,1.34E-4,0.000239,0.192,"0/-","BTK inhibitor","BTK","Kinase inhibitor"]
["BSCL2","Binimetinib",-0.42,0.0366,0.71,0.00204,3.82,1.35E-4,0.000239,0.192,"-/+","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["ABCD3","Selinexor",0.253,0.223,-0.792,0.000255,-3.82,1.35E-4,0.000239,0.192,"0/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["ADD3","AT9283",-0.197,0.345,0.813,0.000129,3.82,1.35E-4,0.000239,0.192,"0/+","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["ZBTB18","Triapine",0.525,0.00705,-0.748,0.000866,-4.43,{"v":9.25e-06,"d":"9.25E-06"},{"v":2.9E-5,"d":"2.90E-05"},0.192,"+/-","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["TRIP4","Onalespib",-0.4,0.0474,0.81,0.000142,4.43,{"v":9.25e-06,"d":"9.25E-06"},{"v":2.9E-5,"d":"2.90E-05"},0.192,"-/+","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["UBASH3A","Gemcitabine",-0.212,0.308,0.871,{"v":1.15E-5,"d":"1.15E-05"},4.43,{"v":9.26e-06,"d":"9.26E-06"},{"v":2.9E-5,"d":"2.90E-05"},0.192,"0/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["TRIM11","Cytarabine",0.708,{"v":7.6e-05,"d":"7.60E-05"},-0.582,0.018,-4.43,{"v":9.62e-06,"d":"9.62E-06"},{"v":2.95e-05,"d":"2.95E-05"},0.192,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ADD3","Docetaxel",-0.0128,0.952,0.867,{"v":1.36E-5,"d":"1.36E-05"},3.82,1.36E-4,2.41E-4,0.193,"0/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["BUB1","Fludarabine",0.569,0.003,-0.597,0.0146,-3.81,1.36E-4,2.42E-4,0.194,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["ALDH1B1","Trametinib",-0.538,0.00559,0.625,0.00968,3.81,0.000138,2.43E-4,0.194,"-/+","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["ITPR3","Glesatinib",-0.668,0.000262,0.648,0.00665,4.51,{"v":6.37E-6,"d":"6.37E-06"},{"v":2.77e-05,"d":"2.77E-05"},0.194,"-/+","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["KIFC1","Selinexor",0.536,0.00576,-0.753,0.000762,-4.51,{"v":6.46E-6,"d":"6.46E-06"},{"v":2.79e-05,"d":"2.79E-05"},0.194,"+/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["SRPK1","Pemetrexed",0.759,{"v":1.08E-5,"d":"1.08E-05"},-0.519,0.0392,-4.49,{"v":7.2e-06,"d":"7.20E-06"},{"v":3.29E-5,"d":"3.29E-05"},0.194,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["TIMM29","Losmapimod",0.165,0.431,-0.886,{"v":4.95E-6,"d":"4.95E-06"},-4.49,{"v":7.25E-6,"d":"7.25E-06"},{"v":3.29E-5,"d":"3.29E-05"},0.194,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["STAU1","Mercaptopurine",0.587,0.00205,-0.714,1.9E-3,-4.48,{"v":7.44e-06,"d":"7.44E-06"},{"v":3.31e-05,"d":"3.31E-05"},0.194,"+/-","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["CBX1","Vorinostat",0.778,{"v":4.59e-06,"d":"4.59E-06"},-0.284,0.287,-3.81,0.000138,0.000246,0.196,"+/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["BUB1B","Pemetrexed",0.741,{"v":2.25e-05,"d":"2.25E-05"},-0.362,0.168,-3.81,0.000139,0.000247,0.196,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["ADGRE5","Litronesib",-0.568,0.00308,0.597,0.0146,3.81,0.000139,0.000248,0.196,"-/+","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["BUB1","Epirubicin",0.468,0.0184,-0.678,0.0039,-3.81,0.00014,0.000249,0.196,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["BLM","Cytarabine",0.608,0.00126,-0.555,0.0255,-3.81,0.00014,0.00025,0.196,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["BLZF1","AZD8055",-0.141,0.5,0.83,{"v":6.81e-05,"d":"6.81E-05"},3.81,0.00014,0.000251,0.196,"0/+","mTOR inhibitor","MTOR","Kinase inhibitor"]
["ANKRD50","AZD1152_HQPA",0.311,0.13,-0.766,0.000543,-3.81,0.000141,0.000251,0.196,"0/-","Aurora B inhibitor","AURKB","Kinase inhibitor"]
["ARL3","Lonafarnib",-0.313,0.127,0.765,0.000559,3.81,0.000141,0.000251,0.196,"0/+","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["ABCC10","BX_912",-0.277,0.18,0.78,0.000361,3.8,0.000142,0.000251,0.196,"0/+","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["ASB3","Vincristine",0.656,0.000374,-0.497,0.0499,-3.8,0.000142,0.000253,0.196,"+/-","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB;TUBA4A","Conv.Chemo"]
["ATP5F1B","Alisertib",-0.366,0.0723,0.739,1.08E-3,3.8,0.000142,0.000253,0.196,"0/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["BRAT1","Carboplatin",0.484,0.0142,-0.665,0.00493,-3.8,0.000143,0.000253,0.196,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["CAPRIN1","Gemcitabine",0.701,{"v":9.57e-05,"d":"9.57E-05"},-0.431,0.0956,-3.8,1.44E-4,0.000253,0.196,"+/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["TMEM245","MK_2206",-0.636,0.000639,0.671,0.00444,4.47,{"v":7.89e-06,"d":"7.89E-06"},{"v":3.44e-05,"d":"3.44E-05"},0.196,"-/+","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["SPAG5","Cytarabine",0.736,{"v":2.76E-5,"d":"2.76E-05"},-0.552,0.0266,-4.47,{"v":7.92e-06,"d":"7.92E-06"},{"v":3.46e-05,"d":"3.46E-05"},0.196,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["SWAP70","Venetoclax",0.649,0.000454,-0.655,0.00587,-4.45,{"v":8.54e-06,"d":"8.54E-06"},{"v":3.61e-05,"d":"3.61E-05"},0.196,"+/-","Bcl-2 selective inhibitor","BCL2","Apoptotic modulator"]
["SKA3","Prexasertib",0.792,{"v":2.43E-6,"d":"2.43E-06"},-0.446,0.0835,-4.45,{"v":8.73e-06,"d":"8.73E-06"},{"v":3.66e-05,"d":"3.66E-05"},0.196,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["SLC22A5","Digoxin",-0.437,0.029,0.795,2.32E-4,4.44,{"v":8.94e-06,"d":"8.94E-06"},{"v":3.74e-05,"d":"3.74E-05"},0.196,"-/+","Cardiac glycoside","ATP1A1;ITGB1;ITGB3;ITGA3;ITGA1","Other"]
["SLIRP","A_1155463",-0.756,{"v":1.26E-5,"d":"1.26E-05"},0.51,0.0436,4.43,{"v":9.58e-06,"d":"9.58E-06"},{"v":3.86e-05,"d":"3.86E-05"},0.196,"-/+","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2","Apoptotic modulator"]
["TCF3","Fludarabine",0.615,1.07E-3,-0.681,0.00371,-4.42,{"v":9.76e-06,"d":"9.76E-06"},{"v":3.96E-5,"d":"3.96E-05"},0.196,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["TLK1","AZD8055",-0.308,0.135,0.842,{"v":4.32E-5,"d":"4.32E-05"},4.42,{"v":1e-05,"d":"1.00E-05"},{"v":4.04e-05,"d":"4.04E-05"},0.196,"0/+","mTOR inhibitor","MTOR","Kinase inhibitor"]
["TARDBP","Trifluridine",0.323,0.115,-0.837,{"v":5.33e-05,"d":"5.33E-05"},-4.42,{"v":1e-05,"d":"1.00E-05"},{"v":4.04e-05,"d":"4.04E-05"},0.196,"0/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["SPRTN","Cytarabine",0.636,0.000639,-0.66,0.00538,-4.41,{"v":1.02e-05,"d":"1.02E-05"},{"v":4.09e-05,"d":"4.09E-05"},0.196,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["TIGD2","Ponatinib",0.0732,0.728,-0.9,{"v":2.11e-06,"d":"2.11E-06"},-4.41,{"v":1.03E-5,"d":"1.03E-05"},{"v":4.09e-05,"d":"4.09E-05"},0.196,"0/-","Broad TK inhibitor","ABL1;PDGFRA;KDR;FGFR1;SRC;KIT","Kinase inhibitor"]
["TMEM219","UNC0638",-0.52,0.0077,0.747,0.000877,4.41,{"v":1.03E-5,"d":"1.03E-05"},{"v":4.09e-05,"d":"4.09E-05"},0.196,"-/+","G9a, GLP inhibitor","EHMT2","Differentiating.epigenetic modifier"]
["TMEM106A","Digoxin",0.163,0.436,-0.881,{"v":6.76e-06,"d":"6.76E-06"},-4.41,{"v":1.04E-5,"d":"1.04E-05"},{"v":4.09e-05,"d":"4.09E-05"},0.196,"0/-","Cardiac glycoside","ATP1A1;ITGB1;ITGB3;ITGA3;ITGA1","Other"]
["ARPP21","Cabozantinib",0.631,0.000713,-0.527,0.0361,-3.8,1.45E-4,0.000255,0.197,"+/-","VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor","KDR;MET;FLT3;KIT;RET;TEK","Kinase inhibitor"]
["ATP6V0D1","GSK_461364",-0.54,5.3E-3,0.619,0.0105,3.8,1.46E-4,0.000257,0.198,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["ARPC5","Cytarabine",-0.385,0.0574,0.727,1.41E-3,3.8,1.46E-4,0.000259,0.198,"0/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["CARM1","RGFP966",0.42,0.0367,-0.707,0.00219,-3.8,1.46E-4,0.000259,0.198,"+/-","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["AASDHPPT","BMS_911543",0.584,2.16E-3,-0.578,0.0191,-3.8,1.47E-4,0.000259,0.198,"+/-","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["ACTR2","Cytarabine",-0.415,0.0392,0.71,0.00208,3.8,1.47E-4,0.00026,0.198,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["AK4","Omacetaxine",-0.136,0.518,0.831,{"v":6.69E-5,"d":"6.69E-05"},3.8,0.000148,0.00026,0.198,"0/+","Protein synthesis inhib (80 S ribosome)","RPL3","Conv.Chemo"]
["CBX6","Amsacrine",-0.407,0.0435,0.714,1.89E-3,3.8,0.000148,2.61E-4,0.198,"-/+","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["BTG3","AT9283",0.517,0.00812,-0.638,0.00782,-3.79,0.000148,2.61E-4,0.198,"+/-","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["ADGRE5","Danusertib",-0.363,0.0742,0.738,1.09E-3,3.79,0.000148,0.000262,0.198,"0/+","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["CBR1","Tozasertib",-0.785,{"v":3.32E-6,"d":"3.32E-06"},0.262,0.327,3.79,0.000148,0.000262,0.198,"-/0","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["AASDHPPT","Pexidartinib",0.702,{"v":9.29e-05,"d":"9.29E-05"},-0.427,0.0989,-3.79,0.000149,2.63E-4,0.198,"+/0","KIT, CSF1R, FLT3 inhibitor","CSF1R;FLT3;KIT","Kinase inhibitor"]
["AKR1A1","Prexasertib",-0.737,{"v":2.68e-05,"d":"2.68E-05"},0.366,0.163,3.79,0.000149,2.63E-4,0.198,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["C10orf88","Amsacrine",0.473,0.0169,-0.671,0.00443,-3.79,0.00015,2.63E-4,0.198,"+/-","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["BRAT1","Aldoxorubicin",0.468,0.0184,-0.675,4.15E-3,-3.79,0.00015,0.000264,0.198,"+/-","Topoisomerase II inhibitor, Albumin binding","TOP2A;TOP2B","Conv.Chemo"]
["ACAA2","Hydroxyurea",-0.257,0.215,0.787,{"v":0.0003,"d":"3.00E-04"},3.79,0.000151,0.000265,0.198,"0/+","Antineoplastic agent","RRM1","Conv.Chemo"]
["ATE1","Pomalidomide",-0.479,0.0154,0.666,0.00484,3.79,0.000151,0.000266,0.198,"-/+","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["CAPRIN1","SN_38",0.681,0.000177,-0.457,0.0751,-3.79,0.000152,0.000266,0.198,"+/0","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["BUB1","Doxorubicin",0.423,0.0351,-0.703,0.00238,-3.79,0.000152,0.000266,0.198,"+/-","Topoisomerase II inhibitor","TOP2A;NOLC1","Conv.Chemo"]
["CARM1","Cisplatin",0.416,0.0388,-0.708,2.16E-3,-3.79,0.000152,0.000269,0.198,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["ARHGAP1","Cytarabine.Idarubicin",-0.601,1.48E-3,0.558,0.0248,3.79,0.000153,0.000269,0.198,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["ANPEP","AZD8055",-0.229,0.272,0.797,0.000215,3.79,1.54E-4,0.000269,0.198,"0/+","mTOR inhibitor","MTOR","Kinase inhibitor"]
["AASDHPPT","Crenolanib",0.502,0.0105,-0.648,0.00664,-3.78,1.54E-4,2.7E-4,0.198,"+/-","PDGFRA and PDGFRB inhibitor","PDGFRA","Kinase inhibitor"]
["CCDC167","Cytarabine",0.792,{"v":2.38e-06,"d":"2.38E-06"},-0.242,0.367,-3.78,1.54E-4,2.7E-4,0.198,"+/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["BRCC3","Sitravatinib",0.515,0.00845,-0.638,0.00786,-3.78,1.54E-4,0.000271,0.198,"+/-","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["CCDC167","ML390",0.695,1.16E-4,-0.435,0.0924,-3.78,1.56E-4,0.000271,0.198,"+/0","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["CAPRIN1","Cladribine",0.559,3.65E-3,-0.598,0.0143,-3.78,0.000157,2.72E-4,0.198,"+/-","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["ARF4","Losmapimod",0.284,0.169,-0.774,4.35E-4,-3.78,0.000157,0.000274,0.199,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["CBX6","Clofarabine",-0.598,0.0016,0.56,0.0242,3.78,0.000157,0.000275,0.199,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["CAPN7","Imiquimod",0.243,0.242,-0.791,0.000265,-3.78,0.000158,0.000275,0.199,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["ADA2","Floxuridine",-0.223,0.285,0.798,0.000209,3.78,0.00016,0.000275,0.199,"0/+","Antimetabolite, Analog of 5-fluorouracil","TYMS","Conv.Chemo"]
["CAD","Abexinostat",-0.646,0.000483,0.502,0.0477,3.77,0.00016,0.000276,0.199,"-/+","HDAC1 selective inhibitor","HDAC1","Differentiating.epigenetic modifier"]
["DNAJA1","Raltitrexed",0.852,{"v":6.54e-08,"d":"6.54E-08"},-0.336,0.203,-4.61,{"v":3.99e-06,"d":"3.99E-06"},{"v":2.47e-05,"d":"2.47E-05"},0.199,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["DDX39A","Methotrexate",0.685,0.000158,-0.65,0.00646,-4.61,{"v":4e-06,"d":"4.00E-06"},{"v":2.47e-05,"d":"2.47E-05"},0.199,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["CD247","AT_101",-0.111,0.599,0.905,{"v":1.46E-6,"d":"1.46E-06"},4.6,{"v":4.18e-06,"d":"4.18E-06"},{"v":2.49e-05,"d":"2.49E-05"},0.199,"0/+","pan Bcl-2 family inhibitor","BCL2;BCL2L1;MCL1","Apoptotic modulator"]
["FEN1","Paclitaxel",-0.328,0.109,0.84,{"v":4.59e-05,"d":"4.59E-05"},4.47,{"v":7.87e-06,"d":"7.87E-06"},{"v":3.34e-05,"d":"3.34E-05"},0.199,"0/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["FAM83D","Rigosertib",0.746,{"v":1.86e-05,"d":"1.86E-05"},-0.535,0.0326,-4.46,{"v":8.07e-06,"d":"8.07E-06"},{"v":3.41e-05,"d":"3.41E-05"},0.199,"+/-","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["FMR1","Mitomycin_C",-0.131,0.532,-0.934,{"v":1.25e-07,"d":"1.25E-07"},-4.45,{"v":8.77e-06,"d":"8.77E-06"},{"v":3.69e-05,"d":"3.69E-05"},0.199,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["EIF3J","Pemetrexed",0.535,0.0059,-0.743,0.000976,-4.44,{"v":8.95e-06,"d":"8.95E-06"},{"v":3.74e-05,"d":"3.74E-05"},0.199,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["ETHE1","Tozasertib",-0.647,0.000474,0.655,0.00593,4.44,{"v":8.99e-06,"d":"8.99E-06"},{"v":3.74e-05,"d":"3.74E-05"},0.199,"-/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["EIF4G2","Prexasertib",0.772,{"v":6.26e-06,"d":"6.26E-06"},-0.483,0.058,-4.44,{"v":9.17e-06,"d":"9.17E-06"},{"v":3.79E-5,"d":"3.79E-05"},0.199,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["FKTN","Cabozantinib",0.495,0.0119,-0.764,0.000564,-4.43,{"v":9.51e-06,"d":"9.51E-06"},{"v":3.91e-05,"d":"3.91E-05"},0.199,"+/-","VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor","KDR;MET;FLT3;KIT;RET;TEK","Kinase inhibitor"]
["GOLGA2","MK_2206",-0.481,0.015,0.771,4.66E-4,4.43,{"v":9.64e-06,"d":"9.64E-06"},{"v":3.99e-05,"d":"3.99E-05"},0.199,"-/+","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["EIF3B","SN_38",0.391,0.0532,-0.813,0.00013,-4.42,{"v":9.67e-06,"d":"9.67E-06"},{"v":3.99e-05,"d":"3.99E-05"},0.199,"0/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["GAB2","LY_2874455",-0.0659,0.754,0.902,{"v":1.85e-06,"d":"1.85E-06"},4.42,{"v":9.85e-06,"d":"9.85E-06"},{"v":4.06e-05,"d":"4.06E-05"},0.199,"0/+","FGFR inhibitor","FGFR1;FGFR2;FGFR3","Kinase inhibitor"]
["EPB41L5","Prexasertib",0.637,0.000617,-0.659,0.00553,-4.41,{"v":1.02e-05,"d":"1.02E-05"},{"v":4.24e-05,"d":"4.24E-05"},0.199,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["FIGNL1","Hydroxyurea",0.602,0.00145,-0.69,0.00312,-4.41,{"v":1.02e-05,"d":"1.02E-05"},{"v":4.24e-05,"d":"4.24E-05"},0.199,"+/-","Antineoplastic agent","RRM1","Conv.Chemo"]
["GPANK1","Methotrexate",0.302,0.142,-0.843,{"v":4.18E-5,"d":"4.18E-05"},-4.41,{"v":1.04E-5,"d":"1.04E-05"},{"v":4.31e-05,"d":"4.31E-05"},0.199,"0/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["HLA-DOA","Gandotinib",-0.627,0.000792,0.667,0.0048,4.41,{"v":1.05e-05,"d":"1.05E-05"},{"v":4.31e-05,"d":"4.31E-05"},0.199,"-/+","JAK2 inhibitor","JAK2;JAK1;FLT3;FLT4;FGFR2;TYK2;NTRK2;FGFR3;KDR;ALK","Kinase inhibitor"]
["FAM102A","Ivosidenib",-0.255,0.218,0.856,{"v":2.31e-05,"d":"2.31E-05"},4.4,{"v":1.07e-05,"d":"1.07E-05"},{"v":4.36e-05,"d":"4.36E-05"},0.199,"0/+","IDH1 R132H and R132C inhibitor","IDH1","Differentiating.epigenetic modifier"]
["HSPA8","Raltitrexed",0.757,{"v":1.2E-5,"d":"1.20E-05"},-0.501,0.0478,-4.4,{"v":1.08E-5,"d":"1.08E-05"},{"v":4.41e-05,"d":"4.41E-05"},0.199,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["ERLEC1","Dactolisib",-0.82,{"v":5.14e-07,"d":"5.14E-07"},0.363,0.167,4.4,{"v":1.09e-05,"d":"1.09E-05"},{"v":4.44e-05,"d":"4.44E-05"},0.199,"-/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;ATR;RPS6KB1","Kinase inhibitor"]
["HDHD5","Fulvestrant",0.566,0.00319,-0.714,0.00187,-4.4,{"v":1.11E-5,"d":"1.11E-05"},{"v":4.49E-5,"d":"4.49E-05"},0.199,"+/-","Estrogen receptor antagonist","ESR1","Hormone therapy"]
["HOXB4","Vismodegib",0.247,0.233,-0.857,{"v":2.2e-05,"d":"2.20E-05"},-4.39,{"v":1.14e-05,"d":"1.14E-05"},{"v":4.54e-05,"d":"4.54E-05"},0.199,"0/-","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["EIF4G2","Gemcitabine",0.663,0.000305,-0.626,0.00952,-4.38,{"v":1.19E-5,"d":"1.19E-05"},{"v":4.64e-05,"d":"4.64E-05"},0.199,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["HES1","EPZ015666",0.558,0.00373,-0.717,0.00178,-4.38,{"v":1.2E-5,"d":"1.20E-05"},{"v":4.66e-05,"d":"4.66E-05"},0.199,"+/-","PRMT5 inhibitor","PRMT5","Differentiating.epigenetic modifier"]
["FIGNL1","Cisplatin",0.49,0.0129,-0.759,0.000652,-4.37,{"v":1.23e-05,"d":"1.23E-05"},{"v":4.76e-05,"d":"4.76E-05"},0.199,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["GSPT1","Prexasertib",0.669,0.000257,-0.618,0.0108,-4.37,{"v":1.23e-05,"d":"1.23E-05"},{"v":4.76e-05,"d":"4.76E-05"},0.199,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["HEMGN","Doramapimod",-0.627,0.000799,0.66,0.00542,4.37,{"v":1.24E-5,"d":"1.24E-05"},{"v":4.88E-5,"d":"4.88E-05"},0.199,"-/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["GRN","Selinexor",-0.275,0.184,0.847,{"v":3.42e-05,"d":"3.42E-05"},4.37,{"v":1.25e-05,"d":"1.25E-05"},{"v":4.88E-5,"d":"4.88E-05"},0.199,"0/+","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["GNG7","Binimetinib",0.358,0.0793,-0.819,1.05E-4,-4.37,{"v":1.27E-5,"d":"1.27E-05"},{"v":4.88E-5,"d":"4.88E-05"},0.199,"0/-","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["HPCAL1","E7820",-0.637,0.000609,0.648,0.00658,4.36,{"v":1.28e-05,"d":"1.28E-05"},{"v":4.91e-05,"d":"4.91E-05"},0.199,"-/+","Integrin alpha2 expression inhibitor","ITGA2","Other"]
["GTPBP10","A_1155463",-0.771,{"v":6.49e-06,"d":"6.49E-06"},0.465,0.0695,4.36,{"v":1.28e-05,"d":"1.28E-05"},{"v":4.93e-05,"d":"4.93E-05"},0.199,"-/0","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2","Apoptotic modulator"]
["KNL1","Prexasertib",0.772,{"v":6.24e-06,"d":"6.24E-06"},-0.498,0.0496,-4.49,{"v":7.04e-06,"d":"7.04E-06"},{"v":2.97E-5,"d":"2.97E-05"},0.199,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["IGHD","AMG319",0.302,0.142,-0.851,{"v":2.96e-05,"d":"2.96E-05"},-4.49,{"v":7.09e-06,"d":"7.09E-06"},{"v":2.97E-5,"d":"2.97E-05"},0.199,"0/-","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["NEU1","GSK269962",-0.256,0.217,0.897,{"v":2.44e-06,"d":"2.44E-06"},4.92,{"v":8.8e-07,"d":"8.80E-07"},{"v":1.02e-05,"d":"1.02E-05"},0.199,"0/+","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["PFDN2","Tozasertib",0.544,0.00493,-0.804,1.75E-4,-4.91,{"v":8.91e-07,"d":"8.91E-07"},{"v":1.02e-05,"d":"1.02E-05"},0.199,"+/-","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["OIP5","Cytarabine",0.628,0.000779,-0.752,0.000781,-4.9,{"v":9.44e-07,"d":"9.44E-07"},{"v":1.05e-05,"d":"1.05E-05"},0.199,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["NFKB2","Imiquimod",-0.253,0.222,0.895,{"v":2.76e-06,"d":"2.76E-06"},4.88,{"v":1.05e-06,"d":"1.05E-06"},{"v":1.1E-5,"d":"1.10E-05"},0.199,"0/+","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["NBEA","Vincristine",0.425,0.0342,-0.844,{"v":3.94e-05,"d":"3.94E-05"},-4.83,{"v":1.38e-06,"d":"1.38E-06"},{"v":1.2E-5,"d":"1.20E-05"},0.199,"+/-","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB;TUBA4A","Conv.Chemo"]
["OIP5","Prexasertib",0.743,{"v":2.06e-05,"d":"2.06E-05"},-0.622,0.01,-4.82,{"v":1.42E-6,"d":"1.42E-06"},{"v":1.2E-5,"d":"1.20E-05"},0.199,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["OIP5","SN_38",0.556,0.00392,-0.78,0.000369,-4.78,{"v":1.78e-06,"d":"1.78E-06"},{"v":1.4E-5,"d":"1.40E-05"},0.199,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["PLEKHM3","Imiquimod",-0.109,0.604,0.915,{"v":6.89e-07,"d":"6.89E-07"},4.76,{"v":1.9E-6,"d":"1.90E-06"},{"v":1.45E-5,"d":"1.45E-05"},0.199,"0/+","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["NFKBIL1","Panobinostat",-0.614,0.0011,0.74,0.00105,4.76,{"v":1.94e-06,"d":"1.94E-06"},{"v":1.47E-5,"d":"1.47E-05"},0.199,"-/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["PIP4K2B","Cytarabine",-0.594,1.73E-3,0.751,0.000793,4.75,{"v":2.07e-06,"d":"2.07E-06"},{"v":1.52E-5,"d":"1.52E-05"},0.199,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["PLD3","Lovastatin",-0.417,0.0379,0.837,{"v":5.34e-05,"d":"5.34E-05"},4.73,{"v":2.25e-06,"d":"2.25E-06"},{"v":1.64e-05,"d":"1.64E-05"},0.199,"-/+","HMG-CoA reductase inhibitor","HMGCR","Metabolic modifier"]
["PIP4K2B","Topotecan",-0.491,0.0128,0.806,0.000161,4.73,{"v":2.27e-06,"d":"2.27E-06"},{"v":1.64e-05,"d":"1.64E-05"},0.199,"-/+","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["MSN","Cytarabine.Idarubicin",-0.707,{"v":7.72e-05,"d":"7.72E-05"},0.646,0.00684,4.72,{"v":2.39E-6,"d":"2.39E-06"},{"v":1.74e-05,"d":"1.74E-05"},0.199,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["MTFR1","PS_1145",-0.254,0.221,0.883,{"v":6.04e-06,"d":"6.04E-06"},4.71,{"v":2.52E-6,"d":"2.52E-06"},{"v":1.82e-05,"d":"1.82E-05"},0.199,"0/+","IKK-2 inhibitor","IKBKB","Kinase inhibitor"]
["P2RX4","8_amino_adenosine",-0.563,0.00342,0.765,0.000558,4.7,{"v":2.6e-06,"d":"2.60E-06"},{"v":1.82e-05,"d":"1.82E-05"},0.199,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["MTFP1","Erlotinib",-0.706,{"v":8.15e-05,"d":"8.15E-05"},0.644,0.00715,4.7,{"v":2.66e-06,"d":"2.66E-06"},{"v":1.82e-05,"d":"1.82E-05"},0.199,"-/+","EGFR inhibitor","EGFR","Kinase inhibitor"]
["NUCB2","GSK2636771",-0.448,0.0246,0.819,1.03E-4,4.68,{"v":2.86e-06,"d":"2.86E-06"},{"v":1.92e-05,"d":"1.92E-05"},0.199,"-/+","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["MTX1","BX_912",0.584,2.15E-3,-0.747,0.000879,-4.68,{"v":2.93e-06,"d":"2.93E-06"},{"v":1.97e-05,"d":"1.97E-05"},0.199,"+/-","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["NAT10","Prexasertib",0.878,{"v":8.45e-09,"d":"8.45E-09"},-0.264,0.324,-4.67,{"v":2.96E-6,"d":"2.96E-06"},{"v":1.97e-05,"d":"1.97E-05"},0.199,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["POLK","NVP_BGT226",-0.316,0.124,0.863,{"v":1.68e-05,"d":"1.68E-05"},4.67,{"v":3.08e-06,"d":"3.08E-06"},{"v":1.99e-05,"d":"1.99E-05"},0.199,"0/+","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CG;MTOR","Kinase inhibitor"]
["PLEKHM3","IOX_2",-0.0359,0.865,0.921,{"v":4.21e-07,"d":"4.21E-07"},4.66,{"v":3.13e-06,"d":"3.13E-06"},{"v":2.02E-5,"d":"2.02E-05"},0.199,"0/+","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["UBASH3A","Daunorubicin",-0.418,0.0374,0.799,2.03E-4,4.41,{"v":1.04E-5,"d":"1.04E-05"},{"v":3.15E-5,"d":"3.15E-05"},0.199,"-/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["WDR62","Fludarabine",0.588,2E-3,-0.7,0.00253,-4.41,{"v":1.05e-05,"d":"1.05E-05"},{"v":3.17e-05,"d":"3.17E-05"},0.199,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["ARHGAP17","Imiquimod",0.00229,0.991,0.867,{"v":1.36E-5,"d":"1.36E-05"},3.77,0.000161,0.000279,0.201,"0/+","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["BYSL","Cladribine",0.446,0.0253,-0.685,0.00339,-3.77,1.63E-4,0.000279,0.201,"+/-","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["C10orf88","Doxorubicin",0.528,0.00669,-0.624,0.00979,-3.77,1.64E-4,2.81E-4,0.201,"+/-","Topoisomerase II inhibitor","TOP2A;NOLC1","Conv.Chemo"]
["RAB15","BMS_911543",-0.0607,0.773,0.912,{"v":8.36e-07,"d":"8.36E-07"},4.58,{"v":4.61e-06,"d":"4.61E-06"},{"v":2.07e-05,"d":"2.07E-05"},0.201,"0/+","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["SREBF2","Daporinad",0.475,0.0165,-0.77,0.000491,-4.39,{"v":1.14e-05,"d":"1.14E-05"},{"v":4.31e-05,"d":"4.31E-05"},0.201,"+/-","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["SLC35B2","Everolimus",-0.547,0.00465,0.726,0.00145,4.39,{"v":1.15E-5,"d":"1.15E-05"},{"v":4.31e-05,"d":"4.31E-05"},0.201,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ABHD17C","Perifosine",-0.237,0.254,0.792,0.000258,3.77,1.65E-4,0.000283,0.202,"0/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["CDC7","Gemcitabine",0.505,0.0101,-0.782,0.000347,-4.59,{"v":4.44e-06,"d":"4.44E-06"},{"v":2.64e-05,"d":"2.64E-05"},0.202,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["DPP7","Prexasertib",-0.736,{"v":2.75e-05,"d":"2.75E-05"},0.578,0.019,4.58,{"v":4.7e-06,"d":"4.70E-06"},{"v":2.69E-5,"d":"2.69E-05"},0.202,"-/+","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["DROSHA","Cytarabine",0.632,6.96E-4,-0.694,0.00285,-4.58,{"v":4.71e-06,"d":"4.71E-06"},{"v":2.69E-5,"d":"2.69E-05"},0.202,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["FAM3A","Sirolimus",-0.436,0.0295,0.784,0.000325,4.35,{"v":1.35e-05,"d":"1.35E-05"},{"v":5.11e-05,"d":"5.11E-05"},0.202,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["FIG4","GSK_461364",-0.518,0.00803,0.739,1.06E-3,4.35,{"v":1.35e-05,"d":"1.35E-05"},{"v":5.16e-05,"d":"5.16E-05"},0.202,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["GNAI2","Prexasertib",-0.68,0.000182,0.6,0.0141,4.35,{"v":1.35e-05,"d":"1.35E-05"},{"v":5.16e-05,"d":"5.16E-05"},0.202,"-/+","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["FBRS","Prexasertib",0.608,0.00126,-0.671,0.00444,-4.34,{"v":1.42E-5,"d":"1.42E-05"},{"v":5.43e-05,"d":"5.43E-05"},0.202,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["HELLS","RGFP966",0.634,0.000674,-0.646,0.00685,-4.33,{"v":1.47E-5,"d":"1.47E-05"},{"v":5.56e-05,"d":"5.56E-05"},0.202,"+/-","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["HMGXB4","Daporinad",-0.582,0.00226,0.691,0.00303,4.33,{"v":1.47E-5,"d":"1.47E-05"},{"v":5.56e-05,"d":"5.56E-05"},0.202,"-/+","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["FKBP5","WEHI_539",-0.673,0.000225,0.603,0.0134,4.33,{"v":1.49E-5,"d":"1.49E-05"},{"v":5.61e-05,"d":"5.61E-05"},0.202,"-/+","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["FABP5","GSK269962",0.648,4.66E-4,-0.631,0.00871,-4.33,{"v":1.49E-5,"d":"1.49E-05"},{"v":5.61e-05,"d":"5.61E-05"},0.202,"+/-","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["FBXO7","Tasquinimod",-0.836,{"v":1.92E-7,"d":"1.92E-07"},0.297,0.265,4.33,{"v":1.49E-5,"d":"1.49E-05"},{"v":5.63E-5,"d":"5.63E-05"},0.202,"-/0","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["GLYR1","Perifosine",0.0263,0.901,-0.903,{"v":1.72E-6,"d":"1.72E-06"},-4.32,{"v":1.54e-05,"d":"1.54E-05"},{"v":5.68e-05,"d":"5.68E-05"},0.202,"0/-","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["GMNN","Etoposide",0.461,0.0204,-0.767,5.22E-4,-4.32,{"v":1.55e-05,"d":"1.55E-05"},{"v":5.68e-05,"d":"5.68E-05"},0.202,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["GNL3L","Tipifarnib",0.616,0.00103,-0.66,0.00542,-4.32,{"v":1.55e-05,"d":"1.55E-05"},{"v":5.68e-05,"d":"5.68E-05"},0.202,"+/-","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["ANXA7","Temsirolimus",-0.626,0.000826,0.525,0.0369,3.76,0.000167,0.000284,0.203,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["STK4","Cytarabine.Idarubicin",-0.424,0.0345,0.793,0.00025,4.38,{"v":1.2E-5,"d":"1.20E-05"},{"v":4.41e-05,"d":"4.41E-05"},0.203,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["TMEM192","Eribulin",-0.364,0.0738,0.818,0.000109,4.38,{"v":1.21e-05,"d":"1.21E-05"},{"v":4.51e-05,"d":"4.51E-05"},0.203,"0/+","Mitotic inhibitor, microtubule depolymerizer","TUBB1","Conv.Chemo"]
["SETD5","Gilteritinib",-0.157,0.455,0.879,{"v":7.2e-06,"d":"7.20E-06"},4.38,{"v":1.21e-05,"d":"1.21E-05"},{"v":4.51e-05,"d":"4.51E-05"},0.203,"0/+","FLT3, AXL inhibitor","FLT3","Kinase inhibitor"]
["EPB41L5","Cytarabine",0.656,0.000367,-0.619,0.0105,-4.32,{"v":1.59E-5,"d":"1.59E-05"},{"v":5.81e-05,"d":"5.81E-05"},0.204,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["HNRNPDL","MK_8745",0.339,0.097,-0.82,1.02E-4,-4.31,{"v":1.61e-05,"d":"1.61E-05"},{"v":5.88e-05,"d":"5.88E-05"},0.204,"0/-","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["FIGNL1","Etoposide",0.657,3.59E-4,-0.617,0.0108,-4.31,{"v":1.62e-05,"d":"1.62E-05"},{"v":5.93e-05,"d":"5.93E-05"},0.204,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["GAB3","Pomalidomide",-0.412,0.0406,0.788,0.000291,4.3,{"v":1.72e-05,"d":"1.72E-05"},{"v":6.18e-05,"d":"6.18E-05"},0.204,"-/+","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["FOXP1","Perifosine",7.43E-3,0.972,-0.904,{"v":1.51e-06,"d":"1.51E-06"},-4.3,{"v":1.73E-5,"d":"1.73E-05"},{"v":6.21e-05,"d":"6.21E-05"},0.204,"0/-","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["HMBS","Topotecan",0.255,0.218,-0.846,{"v":3.62e-05,"d":"3.62E-05"},-4.3,{"v":1.73E-5,"d":"1.73E-05"},{"v":6.21e-05,"d":"6.21E-05"},0.204,"0/-","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["H3-2","Quizartinib",-0.331,0.106,0.821,{"v":9.86e-05,"d":"9.86E-05"},4.29,{"v":1.75e-05,"d":"1.75E-05"},{"v":6.21e-05,"d":"6.21E-05"},0.204,"0/+","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["GLCE","Quizartinib",0.465,0.0193,-0.761,0.000617,-4.29,{"v":1.76e-05,"d":"1.76E-05"},{"v":6.21e-05,"d":"6.21E-05"},0.204,"+/-","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["NAGA","8_amino_adenosine",-0.475,0.0164,0.804,0.000177,4.65,{"v":3.38e-06,"d":"3.38E-06"},{"v":2.14e-05,"d":"2.14E-05"},0.204,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["MTMR2","GSK_461364",0.558,0.00375,-0.757,0.000679,-4.63,{"v":3.64e-06,"d":"3.64E-06"},{"v":2.19E-5,"d":"2.19E-05"},0.204,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["PHF20L1","Pracinostat",0.162,0.44,-0.897,{"v":2.57E-6,"d":"2.57E-06"},-4.62,{"v":3.75e-06,"d":"3.75E-06"},{"v":2.32e-05,"d":"2.32E-05"},0.204,"0/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["NFKBIL1","Givinostat",-0.615,1.08E-3,0.716,1.8E-3,4.62,{"v":3.84e-06,"d":"3.84E-06"},{"v":2.34E-5,"d":"2.34E-05"},0.204,"-/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC10","Differentiating.epigenetic modifier"]
["MTFP1","ODM_201",-0.734,{"v":2.91e-05,"d":"2.91E-05"},0.587,0.0169,4.61,{"v":4.12e-06,"d":"4.12E-06"},{"v":2.39e-05,"d":"2.39E-05"},0.204,"-/+","AR antagonist","AR","Hormone therapy"]
["NFKBIL1","Tubastatin_A",-0.486,0.0137,0.793,0.000251,4.6,{"v":4.22e-06,"d":"4.22E-06"},{"v":2.42e-05,"d":"2.42E-05"},0.204,"-/+","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["OXSM","Perifosine",0.3,0.145,-0.861,{"v":1.88E-5,"d":"1.88E-05"},-4.59,{"v":4.44e-06,"d":"4.44E-06"},{"v":2.52e-05,"d":"2.52E-05"},0.204,"0/-","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["OIP5","Pemetrexed",0.549,0.00448,-0.753,0.000755,-4.57,{"v":4.96e-06,"d":"4.96E-06"},{"v":2.59e-05,"d":"2.59E-05"},0.204,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["NPTN","Cytarabine.Idarubicin",-0.387,0.0562,0.83,{"v":7e-05,"d":"7.00E-05"},4.56,{"v":5.12e-06,"d":"5.12E-06"},{"v":2.64e-05,"d":"2.64E-05"},0.204,"0/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["PCGF1","Vandetanib",0.217,0.298,-0.879,{"v":7.29e-06,"d":"7.29E-06"},-4.55,{"v":5.33e-06,"d":"5.33E-06"},{"v":2.72E-5,"d":"2.72E-05"},0.204,"0/-","VEGFR, EGFR, RET inhibitor","KDR;FLT4;EGFR;RET","Kinase inhibitor"]
["PM20D2","Rocilinostat",-0.727,{"v":3.9e-05,"d":"3.90E-05"},0.584,0.0174,4.55,{"v":5.44e-06,"d":"5.44E-06"},{"v":2.84e-05,"d":"2.84E-05"},0.204,"-/+","HDAC6 selective inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["OPTN","Tozasertib",-0.739,{"v":2.5e-05,"d":"2.50E-05"},0.566,0.0223,4.54,{"v":5.6e-06,"d":"5.60E-06"},{"v":2.87E-5,"d":"2.87E-05"},0.204,"-/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["NIBAN1","Dabrafenib",-0.506,0.00994,0.774,0.000433,4.54,{"v":5.71e-06,"d":"5.71E-06"},{"v":2.89e-05,"d":"2.89E-05"},0.204,"-/+","BRAF(V600E) inhibitor","BRAF;RAF1","Kinase inhibitor"]
["PLEKHA3","Sunitinib",0.593,1.8E-3,-0.719,0.00171,-4.54,{"v":5.74e-06,"d":"5.74E-06"},{"v":2.89e-05,"d":"2.89E-05"},0.204,"+/-","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["NOVA2","MK_8745",0.388,0.0555,-0.826,{"v":7.97e-05,"d":"7.97E-05"},-4.53,{"v":5.84E-6,"d":"5.84E-06"},{"v":2.94E-5,"d":"2.94E-05"},0.204,"0/-","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["PLEKHO2","Dasatinib",-0.467,0.0185,0.792,0.000256,4.52,{"v":6.05e-06,"d":"6.05E-06"},{"v":2.99e-05,"d":"2.99E-05"},0.204,"-/+","ABL, Src, Kit, EphR Inhibitor","ABL1","Kinase inhibitor"]
["ZNF823","Abexinostat",-0.349,0.0869,0.825,{"v":8.43e-05,"d":"8.43E-05"},4.39,{"v":1.12e-05,"d":"1.12E-05"},{"v":3.42e-05,"d":"3.42E-05"},0.204,"0/+","HDAC1 selective inhibitor","HDAC1","Differentiating.epigenetic modifier"]
["WASHC5","Cytarabine",-0.641,0.000558,0.65,0.00636,4.39,{"v":1.13E-5,"d":"1.13E-05"},{"v":3.49e-05,"d":"3.49E-05"},0.204,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["USP1","8_amino_adenosine",0.635,0.000642,-0.655,0.00591,-4.39,{"v":1.16e-05,"d":"1.16E-05"},{"v":3.52e-05,"d":"3.52E-05"},0.204,"+/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["VPS16","ABT_751",-0.561,0.00354,0.715,0.00184,4.38,{"v":1.19E-5,"d":"1.19E-05"},{"v":3.57E-5,"d":"3.57E-05"},0.204,"-/+","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["XRCC1","Vandetanib",0.44,0.0277,-0.786,0.000311,-4.38,{"v":1.19E-5,"d":"1.19E-05"},{"v":3.59e-05,"d":"3.59E-05"},0.204,"+/-","VEGFR, EGFR, RET inhibitor","KDR;FLT4;EGFR;RET","Kinase inhibitor"]
["TXNDC17","Cladribine",0.483,0.0145,-0.763,0.000578,-4.38,{"v":1.2E-5,"d":"1.20E-05"},{"v":3.59e-05,"d":"3.59E-05"},0.204,"+/-","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["AP3M2","Carboplatin",-0.546,0.00471,0.606,0.0129,3.76,0.000169,0.000288,0.205,"-/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["ANXA4","Triapine",-0.47,0.0177,0.667,0.00478,3.76,0.000169,2.9E-4,0.205,"-/+","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["BUB1","Raltitrexed",0.719,{"v":5.12e-05,"d":"5.12E-05"},-0.388,0.137,-3.76,0.00017,0.000291,0.205,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["C5orf51","Axitinib",0.314,0.127,-0.757,0.000677,-3.76,0.00017,2.92E-4,0.205,"0/-","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["ARIH2","Vinblastine",0.244,0.24,-0.788,2.9E-4,-3.76,0.000171,2.92E-4,0.205,"0/-","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["AHSA1","Lonafarnib",0.249,0.23,-0.786,0.000309,-3.76,0.000172,0.000293,0.205,"0/-","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["AC093323.1","AZD1152_HQPA",0.0569,0.787,-0.85,{"v":3.02e-05,"d":"3.02E-05"},-3.76,1.73E-4,0.000295,0.205,"0/-","Aurora B inhibitor","AURKB","Kinase inhibitor"]
["ACAA2","PF_03758309",-0.178,0.394,0.812,0.000133,3.75,1.74E-4,0.000295,0.205,"0/+","PAK4 inhibitor","PAK4","Kinase inhibitor"]
["ANKRD46","Dovitinib",0.49,0.0128,-0.651,0.00631,-3.75,1.74E-4,0.000296,0.205,"+/-","FGFR inhibitor","FGFR1;FGFR3;KIT;FLT3;FLT4","Kinase inhibitor"]
["CACYBP","BX_912",0.355,0.0819,-0.736,1.14E-3,-3.75,1.74E-4,0.000296,0.205,"0/-","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["BRD9","GSK_1070916",0.439,0.028,-0.687,3.3E-3,-3.75,1.74E-4,0.000297,0.205,"+/-","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["ARHGAP18","LY3023414",-0.26,0.21,0.781,3.57E-4,3.75,1.74E-4,0.000297,0.205,"0/+","PI3K, mTOR, DNA-PK inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;PRKDC","Kinase inhibitor"]
["ARHGAP1","Tozasertib",-0.444,0.0262,0.684,0.0035,3.75,1.75E-4,0.000297,0.205,"-/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["ATAT1","UCN_01",0.494,0.0121,-0.648,0.00666,-3.75,1.75E-4,0.000298,0.205,"+/-","PKCbeta, PDK1, Chk, Cdk2 inhibitor","PRKCB;PDPK1","Kinase inhibitor"]
["ACTR3","Cytarabine",-0.405,0.0445,0.708,2.16E-3,3.75,1.75E-4,0.000298,0.205,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ARHGAP23","Cytarabine.Idarubicin",0.489,0.0132,-0.652,0.00622,-3.75,1.75E-4,0.000298,0.205,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["APLP2","Tucidinostat",-0.252,0.224,0.784,3.28E-4,3.75,1.75E-4,2.99E-4,0.205,"0/+","HDAC1, 2, 3 and 10 inhibitor","HDAC1;HDAC2;HDAC3;HDAC10","Differentiating.epigenetic modifier"]
["CASP10","Pemetrexed",-0.622,0.000909,0.526,0.0363,3.75,1.76E-4,2.99E-4,0.205,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["ALDH3A2","BMS_911543",-0.522,0.0075,0.625,0.00959,3.75,1.76E-4,2.99E-4,0.205,"-/+","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["C1orf159","Rigosertib",0.536,5.79E-3,-0.613,0.0115,-3.75,1.76E-4,2.99E-4,0.205,"+/-","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["AAGAB","Lonafarnib",0.491,0.0126,-0.649,0.0065,-3.75,0.000177,{"v":0.0003,"d":"3.00E-04"},0.205,"+/-","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["AK6","Cytarabine",0.515,0.00844,-0.63,0.00887,-3.75,0.000178,{"v":0.0003,"d":"3.00E-04"},0.205,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["AKIRIN2","Cabazitaxel",0.286,0.166,-0.768,0.000508,-3.75,0.00018,3.01E-4,0.205,"0/-","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["ALDH5A1","MK_8745",-0.587,0.00202,0.562,0.0233,3.74,0.00018,0.000303,0.205,"-/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["GAB1","GSK_690693",-0.563,0.0034,0.697,0.00269,4.28,{"v":1.83e-05,"d":"1.83E-05"},{"v":6.43e-05,"d":"6.43E-05"},0.205,"-/+","AKT, PKA, PKC inhibitor","AKT1;AKT2;AKT3;PRKCE;PRKCB;PRKCD;PRKCH;PRKCQ;PRKX;PRKG1","Kinase inhibitor"]
["GSPT1","SN_38",0.528,0.00663,-0.721,0.00161,-4.28,{"v":1.85e-05,"d":"1.85E-05"},{"v":6.45e-05,"d":"6.45E-05"},0.205,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["GMNN","Amsacrine",0.438,0.0286,-0.773,0.000443,-4.28,{"v":1.86e-05,"d":"1.86E-05"},{"v":6.48e-05,"d":"6.48E-05"},0.205,"+/-","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["GNS","Raltitrexed",-0.778,{"v":4.76e-06,"d":"4.76E-06"},0.428,0.0981,4.28,{"v":1.87e-05,"d":"1.87E-05"},{"v":6.48e-05,"d":"6.48E-05"},0.205,"-/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["STAT4","PF_670462",-0.443,0.0267,0.782,0.00034,4.37,{"v":1.27E-5,"d":"1.27E-05"},{"v":4.76e-05,"d":"4.76E-05"},0.205,"-/+","CK1epsilon and CK1delta inhibitor","CSNK1D;CSNK1E","Kinase inhibitor"]
["SPN","8_amino_adenosine",-0.247,0.235,0.855,{"v":2.49e-05,"d":"2.49E-05"},4.36,{"v":1.31E-5,"d":"1.31E-05"},{"v":4.81e-05,"d":"4.81E-05"},0.205,"0/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["STX12","Cabozantinib",0.525,0.00705,-0.735,1.17E-3,-4.35,{"v":1.34E-5,"d":"1.34E-05"},{"v":4.81e-05,"d":"4.81E-05"},0.205,"+/-","VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor","KDR;MET;FLT3;KIT;RET;TEK","Kinase inhibitor"]
["TIMM29","IOX_2",-0.0432,0.838,-0.916,{"v":6.12e-07,"d":"6.12E-07"},-4.35,{"v":1.34E-5,"d":"1.34E-05"},{"v":4.81e-05,"d":"4.81E-05"},0.205,"0/-","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["TXNRD2","Cytarabine",-0.727,{"v":3.79E-5,"d":"3.79E-05"},0.541,0.0303,4.37,{"v":1.23e-05,"d":"1.23E-05"},{"v":3.69e-05,"d":"3.69E-05"},0.206,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ARHGAP17","Perifosine",0.0505,0.811,0.876,{"v":8.53e-06,"d":"8.53E-06"},3.74,1.83E-4,0.000306,0.207,"0/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["C9orf78","AT_406",-0.553,0.00416,0.596,0.0149,3.74,1.83E-4,0.000307,0.207,"-/+","XIAP, cIAP1, cIAP2 inhibitor","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["POLK","Dactolisib",-0.199,0.34,0.88,{"v":6.78e-06,"d":"6.78E-06"},4.52,{"v":6.31e-06,"d":"6.31E-06"},{"v":3.16e-05,"d":"3.16E-05"},0.208,"0/+","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;ATR;RPS6KB1","Kinase inhibitor"]
["NSUN2","Trifluridine",0.751,{"v":1.52E-5,"d":"1.52E-05"},-0.54,0.0308,-4.52,{"v":6.32e-06,"d":"6.32E-06"},{"v":3.16e-05,"d":"3.16E-05"},0.208,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["UBR5","Rigosertib",0.625,0.000847,-0.661,0.00531,-4.36,{"v":1.27E-5,"d":"1.27E-05"},{"v":3.82E-5,"d":"3.82E-05"},0.208,"+/-","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["TRIP13","Alisertib",0.517,0.0082,-0.741,1.01E-3,-4.36,{"v":1.3e-05,"d":"1.30E-05"},{"v":3.89e-05,"d":"3.89E-05"},0.208,"+/-","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["TXNDC9","Prexasertib",0.821,{"v":5.01e-07,"d":"5.01E-07"},-0.346,0.189,-4.35,{"v":1.38E-5,"d":"1.38E-05"},{"v":4.12e-05,"d":"4.12E-05"},0.208,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["WDCP","Ridaforolimus",0.27,0.191,-0.846,{"v":3.6e-05,"d":"3.60E-05"},-4.34,{"v":1.4E-5,"d":"1.40E-05"},{"v":4.17e-05,"d":"4.17E-05"},0.208,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["TOP2A","Prexasertib",0.787,{"v":3.12e-06,"d":"3.12E-06"},-0.428,0.0985,-4.34,{"v":1.4E-5,"d":"1.40E-05"},{"v":4.19e-05,"d":"4.19E-05"},0.208,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["XPNPEP1","Filanesib",-0.594,1.72E-3,0.681,3.65E-3,4.33,{"v":1.46e-05,"d":"1.46E-05"},{"v":4.24e-05,"d":"4.24E-05"},0.208,"-/+","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["ZNRD2","Cladribine",0.584,0.00217,-0.688,0.00319,-4.33,{"v":1.51e-05,"d":"1.51E-05"},{"v":4.34e-05,"d":"4.34E-05"},0.208,"+/-","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["WDR81","WEHI_539",0.579,0.0024,-0.692,2.97E-3,-4.33,{"v":1.51e-05,"d":"1.51E-05"},{"v":4.34e-05,"d":"4.34E-05"},0.208,"+/-","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["WRAP73","BMS863233",0.409,0.0422,-0.792,0.000255,-4.32,{"v":1.55e-05,"d":"1.55E-05"},{"v":4.42e-05,"d":"4.42E-05"},0.208,"+/-","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["WASHC5","SN_38",-0.516,0.00825,0.734,0.0012,4.31,{"v":1.61e-05,"d":"1.61E-05"},{"v":4.52e-05,"d":"4.52E-05"},0.208,"-/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["TUT1","Spebrutinib",-0.572,0.00284,0.695,0.00279,4.31,{"v":1.63E-5,"d":"1.63E-05"},{"v":4.67e-05,"d":"4.67E-05"},0.208,"-/+","BTK inhibitor","BTK","Kinase inhibitor"]
["ZNF101","Cabazitaxel",0.44,0.0279,-0.776,0.000407,-4.31,{"v":1.63E-5,"d":"1.63E-05"},{"v":4.67e-05,"d":"4.67E-05"},0.208,"+/-","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["UBASH3A","Mitoxantrone",-0.47,0.0178,0.76,0.000631,4.31,{"v":1.66E-5,"d":"1.66E-05"},{"v":4.82e-05,"d":"4.82E-05"},0.208,"-/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["USP1","GSK_461364",0.609,1.24E-3,-0.661,0.00527,-4.29,{"v":1.75e-05,"d":"1.75E-05"},{"v":4.89e-05,"d":"4.89E-05"},0.208,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["ZNF185","A_1331852",0.524,0.00713,-0.725,1.48E-3,-4.29,{"v":1.79e-05,"d":"1.79E-05"},{"v":4.94e-05,"d":"4.94E-05"},0.208,"+/-","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2;MCL1","Apoptotic modulator"]
["ZCCHC10","Selumetinib",0.706,{"v":8.16e-05,"d":"8.16E-05"},-0.553,0.0264,-4.29,{"v":1.8E-5,"d":"1.80E-05"},{"v":4.94e-05,"d":"4.94E-05"},0.208,"+/-","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["WDR55","Fingolimod",-0.335,0.102,0.819,1.06E-4,4.29,{"v":1.8E-5,"d":"1.80E-05"},{"v":4.94e-05,"d":"4.94E-05"},0.208,"0/+","S1PR antagonist","S1PR1","Other"]
["TXNDC9","Etoposide",0.686,0.000153,-0.578,0.0191,-4.29,{"v":1.82e-05,"d":"1.82E-05"},{"v":5.04e-05,"d":"5.04E-05"},0.208,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["TP53BP2","Alpelisib",0.319,0.12,-0.824,{"v":8.81E-5,"d":"8.81E-05"},-4.28,{"v":1.83e-05,"d":"1.83E-05"},{"v":5.07e-05,"d":"5.07E-05"},0.208,"0/-","PI3Kalpha selective inhibitor","PIK3CA","Kinase inhibitor"]
["WASHC4","Cytarabine.Idarubicin",-0.509,0.00931,0.734,0.00122,4.28,{"v":1.85e-05,"d":"1.85E-05"},{"v":5.09e-05,"d":"5.09E-05"},0.208,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["VAMP5","Imiquimod",0.0835,0.691,-0.888,{"v":4.32e-06,"d":"4.32E-06"},-4.28,{"v":1.87e-05,"d":"1.87E-05"},{"v":5.14e-05,"d":"5.14E-05"},0.208,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["VBP1","Tozasertib",0.506,0.0099,-0.735,0.00118,-4.28,{"v":1.89e-05,"d":"1.89E-05"},{"v":5.17e-05,"d":"5.17E-05"},0.208,"+/-","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["TROAP","Cytarabine",0.57,0.00294,-0.69,0.0031,-4.27,{"v":1.92e-05,"d":"1.92E-05"},{"v":5.22e-05,"d":"5.22E-05"},0.208,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["TSPO","Everolimus",-0.0913,0.664,0.886,{"v":4.94e-06,"d":"4.94E-06"},4.27,{"v":1.94e-05,"d":"1.94E-05"},{"v":5.22e-05,"d":"5.22E-05"},0.208,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ATG9A","AZD1152_HQPA",-0.277,0.18,0.772,0.000463,3.74,1.83E-4,3.1E-4,0.209,"0/+","Aurora B inhibitor","AURKB","Kinase inhibitor"]
["ADD1","NVP_RAF265",-0.365,0.0726,0.729,0.00137,3.74,1.83E-4,3.1E-4,0.209,"0/+","C-Raf inhibitor, unclear MoA","RAF1;BRAF;KDR","Kinase inhibitor"]
["BUB1","Cisplatin",0.526,0.00698,-0.62,0.0104,-3.74,1.84E-4,0.000311,0.209,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["BTG3","Midostaurin",0.58,0.00238,-0.569,0.0215,-3.74,1.84E-4,0.000312,0.209,"+/-","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["BCAP31","AT13148",-0.519,0.00783,0.625,0.00968,3.74,1.85E-4,0.000312,0.209,"-/+","p70S6K, PKA, ROCK (AKT) inhibitor","AKT1;AKT2;AKT3;RPS6KB1;ROCK1;ROCK2;PRKACA;PRKACB;PRKACG","Kinase inhibitor"]
["ALG2","BMS863233",-0.35,0.0858,0.736,1.16E-3,3.74,0.000186,0.000314,0.209,"0/+","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["BANF1","AMG319",-0.528,0.00665,0.617,0.011,3.74,0.000187,0.000314,0.209,"-/+","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["CAPZB","OSU_03012",-0.69,1.37E-4,0.43,0.0964,3.74,0.000187,0.000315,0.209,"-/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["C10orf88","Onalespib",0.616,0.00104,-0.528,0.0353,-3.74,0.000187,0.000315,0.209,"+/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["ACAA2","Amsacrine",-0.381,0.0601,0.719,0.0017,3.74,0.000187,0.000316,0.209,"0/+","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["BLM","Prexasertib",0.7,{"v":9.84e-05,"d":"9.84E-05"},-0.413,0.112,-3.73,0.000188,0.000317,0.209,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ARHGAP23","Oxaliplatin",0.281,0.173,-0.769,0.000501,-3.73,0.000188,0.000317,0.209,"0/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["AMN1","Prexasertib",0.547,0.00468,-0.599,0.0141,-3.73,0.000189,0.000317,0.209,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ATP9B","Exemestane",-0.432,0.0312,0.688,0.00324,3.73,0.00019,3.19E-4,0.21,"-/+","Aromatase inhibitor","CYP19A1","Hormone therapy"]
["DOCK8","8_amino_adenosine",-0.584,2.15E-3,0.729,0.00136,4.56,{"v":5.1e-06,"d":"5.10E-06"},{"v":2.87E-5,"d":"2.87E-05"},0.21,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["AP2A2","NVP_RAF265",-0.106,0.613,0.833,{"v":6.1e-05,"d":"6.10E-05"},3.73,0.00019,0.00032,0.211,"0/+","C-Raf inhibitor, unclear MoA","RAF1;BRAF;KDR","Kinase inhibitor"]
["CAPRIN1","RGFP966",0.713,{"v":6.39e-05,"d":"6.39E-05"},-0.39,0.135,-3.73,1.92E-4,0.000322,0.211,"+/0","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["BEND3","A_1331852",-0.439,0.0279,0.682,0.0036,3.73,1.92E-4,0.000322,0.211,"-/+","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2;MCL1","Apoptotic modulator"]
["ABI3","Amsacrine",-0.59,1.91E-3,0.556,0.0253,3.73,1.92E-4,0.000324,0.211,"-/+","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["ATP5PF","Litronesib",-0.199,0.341,0.802,0.000189,3.73,1.93E-4,0.000324,0.211,"0/+","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["C1orf112","PCI_34051",0.357,0.0798,-0.731,0.0013,-3.73,1.93E-4,0.000324,0.211,"0/-","HDAC8 inhibitor","HDAC8","Differentiating.epigenetic modifier"]
["AP1B1","BX_912",-0.338,0.0982,0.741,0.00103,3.73,1.94E-4,0.000326,0.212,"0/+","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["ASB7","Imiquimod",0.0887,0.673,0.884,{"v":5.64e-06,"d":"5.64E-06"},3.73,1.94E-4,0.000327,0.212,"0/+","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["ATF6","Quizartinib",0.476,0.0162,-0.656,0.00581,-3.73,1.95E-4,3.28E-4,0.212,"+/-","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["ATAT1","Duvelisib",0.611,0.00118,-0.531,0.0341,-3.72,0.000197,3.28E-4,0.212,"+/-","PI3K inhibitor","PIK3CD","Kinase inhibitor"]
["CAPZB","Pemetrexed",-0.589,0.00193,0.555,0.0257,3.72,0.000197,0.000329,0.212,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["CC2D1B","Gemcitabine",-0.334,0.103,0.742,0.000999,3.72,0.000197,0.000331,0.212,"0/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["C10orf88","AZD1775",0.532,0.00619,-0.61,0.0121,-3.72,0.000198,0.000332,0.212,"+/-","Wee1 inhibitor","WEE1","Kinase inhibitor"]
["CAPZA1","Tamatinib",-0.439,0.028,0.681,0.00371,3.72,0.000198,0.000332,0.212,"-/+","SYK inhibitor","SYK","Kinase inhibitor"]
["APEH","Perifosine",0.11,0.6,-0.831,{"v":6.69E-5,"d":"6.69E-05"},-3.72,0.000198,0.000333,0.212,"0/-","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["ADD3","Litronesib",-0.23,0.268,0.788,0.000287,3.72,0.000199,0.000333,0.212,"0/+","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["ANPEP","NVP_BGT226",-0.212,0.308,0.795,2.32E-4,3.72,{"v":0.0002,"d":"2.00E-04"},0.000333,0.212,"0/+","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CG;MTOR","Kinase inhibitor"]
["MTFR1","Vandetanib",-0.136,0.516,0.893,{"v":3.2e-06,"d":"3.20E-06"},4.5,{"v":6.77e-06,"d":"6.77E-06"},{"v":3.29E-5,"d":"3.29E-05"},0.212,"0/+","VEGFR, EGFR, RET inhibitor","KDR;FLT4;EGFR;RET","Kinase inhibitor"]
["STAM","Rigosertib",-0.407,0.0436,0.796,0.000226,4.34,{"v":1.41e-05,"d":"1.41E-05"},{"v":5.06e-05,"d":"5.06E-05"},0.212,"-/+","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["SPG21","Eribulin",-0.578,2.47E-3,0.694,0.00283,4.33,{"v":1.46e-05,"d":"1.46E-05"},{"v":5.21e-05,"d":"5.21E-05"},0.212,"-/+","Mitotic inhibitor, microtubule depolymerizer","TUBB1","Conv.Chemo"]
["TMEM134","Nelarabine",-0.512,0.00892,0.74,0.00105,4.33,{"v":1.48e-05,"d":"1.48E-05"},{"v":5.26e-05,"d":"5.26E-05"},0.212,"-/+","Antimetabolite, Nucleoside analog, DNA, RNA synth inhibitor","DNA","Conv.Chemo"]
["SPAG5","Raltitrexed",0.798,{"v":1.76e-06,"d":"1.76E-06"},-0.398,0.127,-4.33,{"v":1.49E-5,"d":"1.49E-05"},{"v":5.28e-05,"d":"5.28E-05"},0.212,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["TFDP1","Imiquimod",0.311,0.13,-0.831,{"v":6.76e-05,"d":"6.76E-05"},-4.32,{"v":1.54e-05,"d":"1.54E-05"},{"v":5.36e-05,"d":"5.36E-05"},0.212,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["TIGD2","TAK_530",0.142,0.498,-0.878,{"v":7.93e-06,"d":"7.93E-06"},-4.31,{"v":1.62e-05,"d":"1.62E-05"},{"v":5.61e-05,"d":"5.61E-05"},0.212,"0/-","Pan-HER inhibitor","EGFR;ERBB2;ERBB3","Kinase inhibitor"]
["SKP1","Cytarabine.Idarubicin",0.605,1.34E-3,-0.666,0.00486,-4.3,{"v":1.69e-05,"d":"1.69E-05"},{"v":5.83e-05,"d":"5.83E-05"},0.212,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["TIGD2","Dasatinib",0.0693,0.742,-0.893,{"v":3.32E-6,"d":"3.32E-06"},-4.3,{"v":1.72e-05,"d":"1.72E-05"},{"v":5.93e-05,"d":"5.93E-05"},0.212,"0/-","ABL, Src, Kit, EphR Inhibitor","ABL1","Kinase inhibitor"]
["SLC8A1","Megestrol_acetate",-0.125,0.551,0.88,{"v":7.02e-06,"d":"7.02E-06"},4.29,{"v":1.79e-05,"d":"1.79E-05"},{"v":6.11e-05,"d":"6.11E-05"},0.212,"0/+","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["TFDP1","IOX_2",0.33,0.107,-0.82,{"v":9.94e-05,"d":"9.94E-05"},-4.29,{"v":1.79e-05,"d":"1.79E-05"},{"v":6.11e-05,"d":"6.11E-05"},0.212,"0/-","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["SRP19","Itraconazole",-0.529,0.0065,0.722,0.0016,4.29,{"v":1.79e-05,"d":"1.79E-05"},{"v":6.11e-05,"d":"6.11E-05"},0.212,"-/+","antifungal, hedgehog signaling inhibitor","CYP51A1;CYP3A4","Other"]
["TIGD2","Glesatinib",0.047,0.823,-0.896,{"v":2.6e-06,"d":"2.60E-06"},-4.29,{"v":1.79e-05,"d":"1.79E-05"},{"v":6.11e-05,"d":"6.11E-05"},0.212,"0/-","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["TNFAIP8","Vismodegib",0.338,0.0982,-0.816,1.17E-4,-4.28,{"v":1.89e-05,"d":"1.89E-05"},{"v":6.25e-05,"d":"6.25E-05"},0.212,"0/-","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["SPG21","GSK923295",-0.565,0.00325,0.693,0.0029,4.27,{"v":1.94e-05,"d":"1.94E-05"},{"v":6.35e-05,"d":"6.35E-05"},0.212,"-/+","CENP-E inhibitor","CENPE","Kinesin inhibitor"]
["SLC27A1","Everolimus",-0.599,1.56E-3,0.665,0.00493,4.27,{"v":1.97e-05,"d":"1.97E-05"},{"v":6.43e-05,"d":"6.43E-05"},0.212,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SLC8A1","Litronesib",0.229,0.271,-0.851,{"v":2.91e-05,"d":"2.91E-05"},-4.27,{"v":1.97e-05,"d":"1.97E-05"},{"v":6.43e-05,"d":"6.43E-05"},0.212,"0/-","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["SPG11","AT9283",-0.593,0.00177,0.67,0.00456,4.27,{"v":1.99e-05,"d":"1.99E-05"},{"v":6.43e-05,"d":"6.43E-05"},0.212,"-/+","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["SPAG5","Fludarabine",0.549,4.47E-3,-0.704,2.33E-3,-4.27,{"v":1.99e-05,"d":"1.99E-05"},{"v":6.43e-05,"d":"6.43E-05"},0.212,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["TNKS1BP1","GSK923295",0.38,0.0607,-0.797,0.000216,-4.26,{"v":2e-05,"d":"2.00E-05"},{"v":6.48e-05,"d":"6.48E-05"},0.212,"0/-","CENP-E inhibitor","CENPE","Kinesin inhibitor"]
["TMEM68","Alpelisib",-0.278,0.179,0.836,{"v":5.59e-05,"d":"5.59E-05"},4.26,{"v":2.02E-5,"d":"2.02E-05"},{"v":6.48e-05,"d":"6.48E-05"},0.212,"0/+","PI3Kalpha selective inhibitor","PIK3CA","Kinase inhibitor"]
["SLC25A3","Tubastatin_A",-0.595,0.00171,0.665,0.00493,4.25,{"v":2.13e-05,"d":"2.13E-05"},{"v":6.7e-05,"d":"6.70E-05"},0.212,"-/+","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["SIDT2","Cytarabine",-0.73,{"v":3.39e-05,"d":"3.39E-05"},0.506,0.0457,4.25,{"v":2.15e-05,"d":"2.15E-05"},{"v":6.73e-05,"d":"6.73E-05"},0.212,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["SRPK1","Thioguanine",0.565,0.00325,-0.689,3.16E-3,-4.25,{"v":2.16E-5,"d":"2.16E-05"},{"v":6.73e-05,"d":"6.73E-05"},0.212,"+/-","Antimetabolite, Purine analog","DNMT1","Conv.Chemo"]
["SGO2","Prexasertib",0.774,{"v":5.62e-06,"d":"5.62E-06"},-0.426,0.1,-4.25,{"v":2.18e-05,"d":"2.18E-05"},{"v":6.75e-05,"d":"6.75E-05"},0.212,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["STK11IP","GSK923295",-0.47,0.0176,0.75,0.00081,4.24,{"v":2.2e-05,"d":"2.20E-05"},{"v":6.8e-05,"d":"6.80E-05"},0.212,"-/+","CENP-E inhibitor","CENPE","Kinesin inhibitor"]
["TBCCD1","MK_8745",0.448,0.0248,-0.762,0.000598,-4.24,{"v":2.22e-05,"d":"2.22E-05"},{"v":6.88e-05,"d":"6.88E-05"},0.212,"+/-","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["TMEM134","Clofarabine",-0.539,5.45E-3,0.707,0.0022,4.24,{"v":2.23E-5,"d":"2.23E-05"},{"v":6.88e-05,"d":"6.88E-05"},0.212,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["SMYD3","Cytarabine.Idarubicin",0.467,0.0185,-0.751,0.000801,-4.24,{"v":2.28e-05,"d":"2.28E-05"},{"v":6.95e-05,"d":"6.95E-05"},0.212,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["SGPL1","AT_406",-0.608,0.00128,0.65,0.00639,4.23,{"v":2.31e-05,"d":"2.31E-05"},{"v":7e-05,"d":"7.00E-05"},0.212,"-/+","XIAP, cIAP1, cIAP2 inhibitor","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["TFDP1","Mitomycin_C",0.129,0.538,-0.874,{"v":9.58e-06,"d":"9.58E-06"},-4.23,{"v":2.32e-05,"d":"2.32E-05"},{"v":7.03e-05,"d":"7.03E-05"},0.212,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["SP2","AZD_8186",-0.404,0.0452,0.782,0.00034,4.23,{"v":2.33e-05,"d":"2.33E-05"},{"v":7.03e-05,"d":"7.03E-05"},0.212,"-/+","PI3K beta inhibitor","PIK3CG","Kinase inhibitor"]
["ST6GALNAC4","SB743921",-0.272,0.189,0.834,{"v":5.97e-05,"d":"5.97E-05"},4.23,{"v":2.35e-05,"d":"2.35E-05"},{"v":7.1e-05,"d":"7.10E-05"},0.212,"0/+","Mitotic inhibitor, Eg5, KSP inhibitor","KIF11","Kinesin inhibitor"]
["SWAP70","Navitoclax",0.766,{"v":8.06e-06,"d":"8.06E-06"},-0.436,0.091,-4.23,{"v":2.38e-05,"d":"2.38E-05"},{"v":7.18e-05,"d":"7.18E-05"},0.212,"+/0","Bcl-2,Bcl-XL inhibitor","BCL2;BCL2L2;BAD;BCL2L1;MCL1","Apoptotic modulator"]
["SIDT2","GSK269962",-0.6,0.00153,0.656,0.00583,4.22,{"v":2.4e-05,"d":"2.40E-05"},{"v":7.2e-05,"d":"7.20E-05"},0.212,"-/+","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["SKP1","Oxaliplatin",0.615,1.07E-3,-0.641,0.00746,-4.22,{"v":2.43e-05,"d":"2.43E-05"},{"v":7.28e-05,"d":"7.28E-05"},0.212,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["TMEM192","Pomalidomide",0.317,0.123,-0.817,1.12E-4,-4.22,{"v":2.47e-05,"d":"2.47E-05"},{"v":7.35e-05,"d":"7.35E-05"},0.212,"0/-","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["SMIM20","TAK_530",0.038,0.857,-0.893,{"v":3.22e-06,"d":"3.22E-06"},-4.22,{"v":2.49e-05,"d":"2.49E-05"},{"v":7.45e-05,"d":"7.45E-05"},0.212,"0/-","Pan-HER inhibitor","EGFR;ERBB2;ERBB3","Kinase inhibitor"]
["SLC27A1","Cytarabine.Idarubicin",-0.79,{"v":2.62e-06,"d":"2.62E-06"},0.381,0.145,4.21,{"v":2.54e-05,"d":"2.54E-05"},{"v":7.6e-05,"d":"7.60E-05"},0.212,"-/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["SRGAP3","Rucaparib",-0.379,0.062,0.791,0.000264,4.21,{"v":2.56e-05,"d":"2.56E-05"},{"v":7.68e-05,"d":"7.68E-05"},0.212,"0/+","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["SPN","Everolimus",-0.436,0.0294,0.764,0.000573,4.21,{"v":2.57e-05,"d":"2.57E-05"},{"v":7.68e-05,"d":"7.68E-05"},0.212,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SYNE2","CCT196969",-0.643,0.000525,0.61,0.0122,4.21,{"v":2.58E-5,"d":"2.58E-05"},{"v":7.7e-05,"d":"7.70E-05"},0.212,"-/+","pan-RAF, Src inhibitor","RAF1;BRAF;SRC;LCK","Kinase inhibitor"]
["SIRT1","Raltitrexed",0.686,0.000152,-0.559,0.0245,-4.21,{"v":2.58E-5,"d":"2.58E-05"},{"v":7.7e-05,"d":"7.70E-05"},0.212,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["STRN","Pemetrexed",-0.481,0.0149,0.739,1.08E-3,4.21,{"v":2.58E-5,"d":"2.58E-05"},{"v":7.7e-05,"d":"7.70E-05"},0.212,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["SYNE1","A_1155463",0.711,{"v":6.74e-05,"d":"6.74E-05"},-0.524,0.0371,-4.21,{"v":2.58E-5,"d":"2.58E-05"},{"v":7.7e-05,"d":"7.70E-05"},0.212,"+/-","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2","Apoptotic modulator"]
["ST6GALNAC4","Imiquimod",-0.0555,0.792,0.889,{"v":4.19e-06,"d":"4.19E-06"},4.21,{"v":2.59e-05,"d":"2.59E-05"},{"v":7.73e-05,"d":"7.73E-05"},0.212,"0/+","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["TMC6","RGFP966",-0.52,0.00772,0.714,1.89E-3,4.21,{"v":2.59e-05,"d":"2.59E-05"},{"v":7.78e-05,"d":"7.78E-05"},0.212,"-/+","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["STYX","TGR_1202",-0.281,0.174,0.828,{"v":7.56e-05,"d":"7.56E-05"},4.2,{"v":2.67e-05,"d":"2.67E-05"},{"v":7.92e-05,"d":"7.92E-05"},0.212,"0/+","PI3Kdelta inhibitor","PIK3CD","Kinase inhibitor"]
["TMC6","8_amino_adenosine",-0.572,0.00283,0.674,0.00416,4.2,{"v":2.68e-05,"d":"2.68E-05"},{"v":7.97e-05,"d":"7.97E-05"},0.212,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["STK11IP","Rigosertib",-0.619,0.00098,0.632,8.6E-3,4.2,{"v":2.72E-5,"d":"2.72E-05"},{"v":8.07e-05,"d":"8.07E-05"},0.212,"-/+","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["SPG11","RGFP966",-0.77,{"v":6.69e-06,"d":"6.69E-06"},0.418,0.107,4.19,{"v":2.76E-5,"d":"2.76E-05"},{"v":8.1e-05,"d":"8.10E-05"},0.212,"-/0","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["TMEM43","Cytarabine",-0.748,{"v":1.73E-5,"d":"1.73E-05"},0.461,0.0725,4.19,{"v":2.77e-05,"d":"2.77E-05"},{"v":8.17e-05,"d":"8.17E-05"},0.212,"-/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["SPN","Sirolimus",-0.398,0.0489,0.78,0.000366,4.19,{"v":2.77e-05,"d":"2.77E-05"},{"v":8.17e-05,"d":"8.17E-05"},0.212,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ACSF3","Vidofludimus",-0.533,0.00612,0.608,0.0124,3.72,2.02E-4,0.000334,0.213,"-/+","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["GNG2","AT9283",-0.708,{"v":7.54e-05,"d":"7.54E-05"},0.544,0.0293,4.27,{"v":1.97e-05,"d":"1.97E-05"},{"v":6.78e-05,"d":"6.78E-05"},0.213,"-/+","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["LRPPRC","A_1155463",-0.756,{"v":1.22E-5,"d":"1.22E-05"},0.523,0.0378,4.48,{"v":7.43E-6,"d":"7.43E-06"},{"v":3.24e-05,"d":"3.24E-05"},0.213,"-/+","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2","Apoptotic modulator"]
["C12orf45","RGFP966",0.456,0.0219,-0.668,0.0047,-3.71,2.04E-4,0.000336,0.214,"+/-","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["METTL17","Pracinostat",-0.767,{"v":7.79E-6,"d":"7.79E-06"},0.502,0.0477,4.47,{"v":7.77e-06,"d":"7.77E-06"},{"v":3.34e-05,"d":"3.34E-05"},0.214,"-/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["KCNAB2","Cytarabine.Idarubicin",-0.733,{"v":3.11e-05,"d":"3.11E-05"},0.555,0.0257,4.46,{"v":8.24e-06,"d":"8.24E-06"},{"v":3.46e-05,"d":"3.46E-05"},0.214,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["MGST2","VER_155008",-0.507,0.00974,0.762,0.000601,4.46,{"v":8.29e-06,"d":"8.29E-06"},{"v":3.49e-05,"d":"3.49E-05"},0.214,"-/+","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["MAP3K1","AMG319",0.543,0.00506,-0.739,1.06E-3,-4.45,{"v":8.53e-06,"d":"8.53E-06"},{"v":3.54E-5,"d":"3.54E-05"},0.214,"+/-","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["LIPA","Prexasertib",-0.801,{"v":1.54e-06,"d":"1.54E-06"},0.426,0.0998,4.45,{"v":8.72e-06,"d":"8.72E-06"},{"v":3.59e-05,"d":"3.59E-05"},0.214,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["KATNA1","GSK_461364",0.568,0.00307,-0.721,0.00162,-4.44,{"v":8.85E-6,"d":"8.85E-06"},{"v":3.61e-05,"d":"3.61E-05"},0.214,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["SF3A2","MK_2206",0.507,0.00966,-0.719,0.00169,-4.19,{"v":2.83E-5,"d":"2.83E-05"},{"v":8.3e-05,"d":"8.30E-05"},0.214,"+/-","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["STAM","Eribulin",-0.19,0.364,0.854,{"v":2.57e-05,"d":"2.57E-05"},4.18,{"v":2.91e-05,"d":"2.91E-05"},{"v":8.57e-05,"d":"8.57E-05"},0.214,"0/+","Mitotic inhibitor, microtubule depolymerizer","TUBB1","Conv.Chemo"]
["TNKS2","8_amino_adenosine",0.414,0.0398,-0.77,0.00048,-4.18,{"v":2.95e-05,"d":"2.95E-05"},{"v":8.6e-05,"d":"8.60E-05"},0.214,"+/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["TAF8","Prexasertib",0.668,0.000265,-0.574,0.0201,-4.17,{"v":3.01E-5,"d":"3.01E-05"},{"v":8.65e-05,"d":"8.65E-05"},0.214,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["TBCC","Nilotinib",-0.388,0.0556,0.781,3.5E-4,4.17,{"v":3.07e-05,"d":"3.07E-05"},{"v":8.77e-05,"d":"8.77E-05"},0.214,"0/+","ABL inhibitor","ABL1;KIT","Kinase inhibitor"]
["STRAP","RGFP966",0.362,0.0749,-0.792,0.000257,-4.16,{"v":3.15E-5,"d":"3.15E-05"},{"v":8.92E-5,"d":"8.92E-05"},0.214,"0/-","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["SSR1","Sirolimus",-0.593,0.00178,0.648,0.00661,4.16,{"v":3.2e-05,"d":"3.20E-05"},{"v":9.02e-05,"d":"9.02E-05"},0.214,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SKA2","Prexasertib",0.782,{"v":3.83e-06,"d":"3.83E-06"},-0.381,0.145,-4.15,{"v":3.28e-05,"d":"3.28E-05"},{"v":9.17e-05,"d":"9.17E-05"},0.214,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["SERPINB6","Volasertib",-0.518,0.008,0.706,0.00224,4.15,{"v":3.29E-5,"d":"3.29E-05"},{"v":9.22e-05,"d":"9.22E-05"},0.214,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["TNKS1BP1","Rigosertib",0.378,0.0626,-0.784,0.000329,-4.15,{"v":3.31e-05,"d":"3.31E-05"},{"v":9.22e-05,"d":"9.22E-05"},0.214,"0/-","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["SNX22","Givinostat",0.534,0.00599,-0.694,0.00284,-4.15,{"v":3.33e-05,"d":"3.33E-05"},{"v":9.25e-05,"d":"9.25E-05"},0.214,"+/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC10","Differentiating.epigenetic modifier"]
["TNKS2","Cytarabine.Idarubicin",0.587,0.00206,-0.652,0.00619,-4.15,{"v":3.34e-05,"d":"3.34E-05"},{"v":9.25e-05,"d":"9.25E-05"},0.214,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["TNFAIP8L2","Cytarabine.Idarubicin",-0.51,0.00919,0.71,0.00204,4.15,{"v":3.37e-05,"d":"3.37E-05"},{"v":9.27e-05,"d":"9.27E-05"},0.214,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["TMEM219","Capmatinib",-0.821,{"v":5.02e-07,"d":"5.02E-07"},0.282,0.29,4.14,{"v":3.45e-05,"d":"3.45E-05"},{"v":9.52e-05,"d":"9.52E-05"},0.214,"-/0","MET inhibitor","MET","Kinase inhibitor"]
["SLC35B2","Sirolimus",-0.488,0.0132,0.723,0.00154,4.14,{"v":3.47e-05,"d":"3.47E-05"},{"v":9.57e-05,"d":"9.57E-05"},0.214,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SF3B4","CC_223",0.543,0.00503,-0.686,0.00336,-4.14,{"v":3.47e-05,"d":"3.47E-05"},{"v":9.57e-05,"d":"9.57E-05"},0.214,"+/-","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["SLC4A2","Saracatinib",-0.394,0.0516,0.775,0.000424,4.14,{"v":3.47e-05,"d":"3.47E-05"},{"v":9.57e-05,"d":"9.57E-05"},0.214,"0/+","Src, ABL inhibitor","ABL1;SRC;LCK;YES1;LYN;FYN;BLK;EGFR;KIT;EPHA2","Kinase inhibitor"]
["TCEAL4","Nelarabine",-0.265,0.201,0.826,{"v":7.93e-05,"d":"7.93E-05"},4.14,{"v":3.48e-05,"d":"3.48E-05"},{"v":9.57e-05,"d":"9.57E-05"},0.214,"0/+","Antimetabolite, Nucleoside analog, DNA, RNA synth inhibitor","DNA","Conv.Chemo"]
["SNRPA","Quizartinib",-0.538,0.0055,0.689,3.16E-3,4.14,{"v":3.5e-05,"d":"3.50E-05"},{"v":9.62e-05,"d":"9.62E-05"},0.214,"-/+","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["SORD","Merestinib",0.429,0.0325,-0.757,0.000685,-4.14,{"v":3.51e-05,"d":"3.51E-05"},{"v":9.62e-05,"d":"9.62E-05"},0.214,"+/-","MET inhibitor","MET","Kinase inhibitor"]
["STYX","KU_60019",-0.471,0.0174,0.733,1.23E-3,4.14,{"v":3.52e-05,"d":"3.52E-05"},{"v":9.62e-05,"d":"9.62E-05"},0.214,"-/+","ATM inhibitor","ATM","Kinase inhibitor"]
["TMEM192","Paclitaxel",-0.323,0.116,0.805,0.000171,4.13,{"v":3.57E-5,"d":"3.57E-05"},{"v":9.77e-05,"d":"9.77E-05"},0.214,"0/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["SIRT1","Pemetrexed",0.62,0.000956,-0.618,0.0108,-4.13,{"v":3.58e-05,"d":"3.58E-05"},{"v":9.84e-05,"d":"9.84E-05"},0.214,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["SLC38A1","Enzalutamide",0.399,0.0482,-0.771,0.000474,-4.13,{"v":3.64e-05,"d":"3.64E-05"},{"v":9.94e-05,"d":"9.94E-05"},0.214,"+/-","AR antagonist","AR","Hormone therapy"]
["SMIM20","Lifirafenib_BGB_283",0.0926,0.66,-0.874,{"v":9.43e-06,"d":"9.43E-06"},-4.13,{"v":3.65E-5,"d":"3.65E-05"},{"v":9.94e-05,"d":"9.94E-05"},0.214,"0/-","Raf inhibitor","RAF1;BRAF;EGFR","Kinase inhibitor"]
["SYNE2","Glesatinib",-0.53,0.00648,0.692,2.99E-3,4.12,{"v":3.81e-05,"d":"3.81E-05"},1.01E-4,0.214,"-/+","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["SPG11","Tozasertib",-0.703,{"v":8.75e-05,"d":"8.75E-05"},0.513,0.0422,4.12,{"v":3.82E-5,"d":"3.82E-05"},1.01E-4,0.214,"-/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["SETD1A","Trifluridine",-0.638,6.02E-4,0.595,0.015,4.12,{"v":3.83e-05,"d":"3.83E-05"},1.01E-4,0.214,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["SHQ1","BIIB021",0.447,0.0253,-0.744,0.000948,-4.12,{"v":3.85e-05,"d":"3.85E-05"},1.01E-4,0.214,"+/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["SLC27A1","Cytarabine",-0.789,{"v":2.74E-6,"d":"2.74E-06"},0.354,0.178,4.12,{"v":3.85e-05,"d":"3.85E-05"},1.01E-4,0.214,"-/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["SLC35F2","Seliciclib",0.257,0.216,-0.827,{"v":7.91e-05,"d":"7.91E-05"},-4.12,{"v":3.87e-05,"d":"3.87E-05"},1.02E-4,0.214,"0/-","CDK2, 7, 9 inhibitor","CDK2;CDK1;CDK5;MAPK1;MAPK3","Kinase inhibitor"]
["SLC35B2","NVP_BGT226",-0.595,1.72E-3,0.637,0.00791,4.11,{"v":3.91e-05,"d":"3.91E-05"},1.03E-4,0.214,"-/+","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CG;MTOR","Kinase inhibitor"]
["SH3BP2","Tozasertib",-0.56,3.62E-3,0.668,0.00472,4.11,{"v":3.91e-05,"d":"3.91E-05"},1.03E-4,0.214,"-/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["SRC","Dabrafenib",0.292,0.156,-0.813,1.27E-4,-4.11,{"v":3.95e-05,"d":"3.95E-05"},1.03E-4,0.214,"0/-","BRAF(V600E) inhibitor","BRAF;RAF1","Kinase inhibitor"]
["ATL3","Ribociclib",-0.571,0.00287,0.572,0.0207,3.71,2.04E-4,3.39E-4,0.215,"-/+","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["AP3S1","Pemetrexed",-0.482,0.0146,0.649,0.00658,3.71,2.05E-4,0.000342,0.216,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["ARID3B","Nilotinib",-0.165,0.43,0.812,1.35E-4,3.71,0.000206,0.000342,0.216,"0/+","ABL inhibitor","ABL1;KIT","Kinase inhibitor"]
["ACSF2","8_amino_adenosine",-0.59,1.89E-3,0.551,0.0269,3.71,0.000206,0.000344,0.216,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["BCKDK","CC_223",-0.462,0.0202,0.664,0.00507,3.71,0.000206,0.000344,0.216,"-/+","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["ACSL4","Glesatinib",0.763,{"v":9.29e-06,"d":"9.29E-06"},-0.287,0.281,-3.71,0.000207,0.000344,0.216,"+/0","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["C1QBP","Masitinib",0.287,0.164,-0.763,0.000589,-3.71,0.000207,0.000345,0.216,"0/-","KIT inhibitor","KIT","Kinase inhibitor"]
["ACSF2","Cytarabine",-0.626,0.000826,0.511,0.0431,3.71,0.000207,0.000345,0.216,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["AC118549.1","Crenolanib",0.511,0.00909,-0.625,0.00957,-3.71,0.000208,0.000345,0.216,"+/-","PDGFRA and PDGFRB inhibitor","PDGFRA","Kinase inhibitor"]
["ABRACL","Cisplatin",-0.436,0.0292,0.68,0.00374,3.71,0.000209,0.000346,0.216,"-/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["ATP5F1A","Alisertib",-0.366,0.0724,0.723,1.56E-3,3.71,0.00021,0.000347,0.216,"0/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["ANXA7","NVP_BGT226",-0.712,{"v":6.59e-05,"d":"6.59E-05"},0.385,0.141,3.71,0.000211,0.000347,0.216,"-/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CG;MTOR","Kinase inhibitor"]
["CCDC136","Pictilisib",0.639,0.000589,-0.493,0.0524,-3.7,2.12E-4,3.48E-4,0.216,"+/0","PI3K inhibitor, pan-class I","PIK3CA;PIK3CB;PIK3CG;PIK3CD;MTOR","Kinase inhibitor"]
["ABHD16A","GSK923295",-0.427,0.0334,0.686,0.00337,3.7,2.13E-4,0.000349,0.216,"-/+","CENP-E inhibitor","CENPE","Kinesin inhibitor"]
["ADCK1","AMG319",-0.506,0.0099,0.628,0.00916,3.7,2.13E-4,0.000349,0.216,"-/+","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["ARHGAP26","Ipatasertib",-0.452,0.0233,0.668,0.00465,3.7,2.14E-4,0.000351,0.216,"-/+","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["SFT2D3","Doxorubicin",0.656,0.00037,-0.572,0.0206,-4.11,{"v":4.04e-05,"d":"4.04E-05"},1.05E-4,0.216,"+/-","Topoisomerase II inhibitor","TOP2A;NOLC1","Conv.Chemo"]
["BZW2","Sabutoclax",0.148,0.48,0.894,{"v":2.95e-06,"d":"2.95E-06"},3.7,0.000216,0.000352,0.217,"0/+","pan Bcl-2 family inhibitor","BCL2;BCL2L1;MCL1;BCL2A1","Apoptotic modulator"]
["CASP10","GSK_1070916",-0.555,0.004,0.584,0.0175,3.7,0.000216,0.000353,0.217,"-/+","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["TSPO","Sirolimus",-0.159,0.449,0.869,{"v":1.22E-5,"d":"1.22E-05"},4.26,{"v":2.03e-05,"d":"2.03E-05"},{"v":5.49E-5,"d":"5.49E-05"},0.217,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ZC4H2","Pexidartinib",0.758,{"v":1.12e-05,"d":"1.12E-05"},-0.459,0.0737,-4.25,{"v":2.1e-05,"d":"2.10E-05"},{"v":5.67e-05,"d":"5.67E-05"},0.217,"+/0","KIT, CSF1R, FLT3 inhibitor","CSF1R;FLT3;KIT","Kinase inhibitor"]
["USP42","Amsacrine",0.259,0.211,-0.84,{"v":4.58e-05,"d":"4.58E-05"},-4.25,{"v":2.11e-05,"d":"2.11E-05"},{"v":5.67e-05,"d":"5.67E-05"},0.217,"0/-","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["TROAP","SN_38",0.629,0.000756,-0.632,0.00856,-4.25,{"v":2.18e-05,"d":"2.18E-05"},{"v":5.74e-05,"d":"5.74E-05"},0.217,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["ZNF507","Cabazitaxel",0.604,0.00138,-0.656,0.00583,-4.24,{"v":2.19E-5,"d":"2.19E-05"},{"v":5.77E-5,"d":"5.77E-05"},0.217,"+/-","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["ZNHIT6","VER_155008",0.484,0.0143,-0.742,1E-3,-4.24,{"v":2.26E-5,"d":"2.26E-05"},{"v":5.92e-05,"d":"5.92E-05"},0.217,"+/-","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["UNC93B1","Everolimus",-0.519,0.00789,0.72,1.67E-3,4.24,{"v":2.28e-05,"d":"2.28E-05"},{"v":5.97e-05,"d":"5.97E-05"},0.217,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["XPNPEP1","Decitabine",-0.688,0.000143,0.563,0.0232,4.24,{"v":2.28e-05,"d":"2.28E-05"},{"v":5.97e-05,"d":"5.97E-05"},0.217,"-/+","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["ZNF485","ENMD_2076",0.605,0.00136,-0.651,0.00632,-4.22,{"v":2.4e-05,"d":"2.40E-05"},{"v":6.24e-05,"d":"6.24E-05"},0.217,"+/-","pan-Aurora, VEGFR inhibitor","AURKA;FLT3;RET;FLT4;SRC;CSF1R;NTRK1;PDGFRA;BLK;KDR;YES1;FYN;AURKB;PTK2;FGFR2;FGFR1;JAK2;KIT;ABL1","Kinase inhibitor"]
["ZNF101","Hydroxyurea",0.679,0.00019,-0.572,0.0207,-4.22,{"v":2.41E-5,"d":"2.41E-05"},{"v":6.27e-05,"d":"6.27E-05"},0.217,"+/-","Antineoplastic agent","RRM1","Conv.Chemo"]
["ZNF507","AT9283",0.627,0.000791,-0.629,0.00901,-4.22,{"v":2.42e-05,"d":"2.42E-05"},{"v":6.29e-05,"d":"6.29E-05"},0.217,"+/-","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["WDR55","BI_2536",0.465,0.0193,-0.749,0.000832,-4.22,{"v":2.5e-05,"d":"2.50E-05"},{"v":6.49e-05,"d":"6.49E-05"},0.217,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["ZNF101","Docetaxel",0.507,0.00971,-0.724,0.00153,-4.21,{"v":2.52e-05,"d":"2.52E-05"},{"v":6.52e-05,"d":"6.52E-05"},0.217,"+/-","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["TRIP10","Canertinib",-0.544,0.00492,0.698,2.63E-3,4.21,{"v":2.52e-05,"d":"2.52E-05"},{"v":6.54e-05,"d":"6.54E-05"},0.217,"-/+","Pan-HER inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["USP16","Gemcitabine",0.582,0.00226,-0.668,0.0047,-4.21,{"v":2.56e-05,"d":"2.56E-05"},{"v":6.57e-05,"d":"6.57E-05"},0.217,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["WDR62","Clofarabine",0.618,0.000988,-0.634,0.00829,-4.21,{"v":2.61e-05,"d":"2.61E-05"},{"v":6.67e-05,"d":"6.67E-05"},0.217,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["TUBGCP6","Sepantronium_bromide",-0.354,0.0829,0.801,1.95E-4,4.2,{"v":2.65E-5,"d":"2.65E-05"},{"v":6.84e-05,"d":"6.84E-05"},0.217,"0/+","Survivin inhibitor","BIRC5","Apoptotic modulator"]
["ZNF512B","Disulfiram_CuCl2",0.127,0.545,-0.872,{"v":1.07e-05,"d":"1.07E-05"},-4.2,{"v":2.67e-05,"d":"2.67E-05"},{"v":6.96e-05,"d":"6.96E-05"},0.217,"0/-","alcohol dehydrogenase inhibitor","ALDH1A1","Metabolic modifier"]
["USP35","Ravoxertinib",-0.131,0.532,0.871,{"v":1.13E-5,"d":"1.13E-05"},4.2,{"v":2.68e-05,"d":"2.68E-05"},{"v":6.99e-05,"d":"6.99E-05"},0.217,"0/+","ERK inhibitor","MAPK3","Kinase inhibitor"]
["VTA1","Mercaptopurine",0.568,0.00303,-0.677,0.00397,-4.2,{"v":2.68e-05,"d":"2.68E-05"},{"v":6.99e-05,"d":"6.99E-05"},0.217,"+/-","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["ZC4H2","ENMD_2076",0.586,0.00207,-0.662,0.00521,-4.2,{"v":2.69E-5,"d":"2.69E-05"},{"v":6.99e-05,"d":"6.99E-05"},0.217,"+/-","pan-Aurora, VEGFR inhibitor","AURKA;FLT3;RET;FLT4;SRC;CSF1R;NTRK1;PDGFRA;BLK;KDR;YES1;FYN;AURKB;PTK2;FGFR2;FGFR1;JAK2;KIT;ABL1","Kinase inhibitor"]
["ZZEF1","Alisertib",-0.554,0.00405,0.688,0.00323,4.2,{"v":2.71e-05,"d":"2.71E-05"},{"v":6.99e-05,"d":"6.99E-05"},0.217,"-/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["TROAP","Topotecan",0.526,0.0069,-0.708,0.00217,-4.19,{"v":2.74e-05,"d":"2.74E-05"},{"v":7.01e-05,"d":"7.01E-05"},0.217,"+/-","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["ZNF430","Ganetespib",-0.503,0.0104,0.723,1.56E-3,4.19,{"v":2.78e-05,"d":"2.78E-05"},{"v":7.09e-05,"d":"7.09E-05"},0.217,"-/+","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["VBP1","AT9283",0.369,0.0691,-0.792,0.000254,-4.19,{"v":2.81e-05,"d":"2.81E-05"},{"v":7.21e-05,"d":"7.21E-05"},0.217,"0/-","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["ZBTB10","GSK_461364",0.612,1.16E-3,-0.637,0.00795,-4.19,{"v":2.82e-05,"d":"2.82E-05"},{"v":7.29e-05,"d":"7.29E-05"},0.217,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["TRMT11","Salinomycin",0.614,1.08E-3,-0.634,0.00829,-4.19,{"v":2.82e-05,"d":"2.82E-05"},{"v":7.29e-05,"d":"7.29E-05"},0.217,"+/-","Ionophore","ABCB1","Other"]
["WASHC4","SN_38",-0.408,0.0429,0.775,4.26E-4,4.19,{"v":2.82e-05,"d":"2.82E-05"},{"v":7.29e-05,"d":"7.29E-05"},0.217,"-/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["XPR1","Cytarabine",0.629,0.000762,-0.62,0.0105,-4.18,{"v":2.86e-05,"d":"2.86E-05"},{"v":7.39e-05,"d":"7.39E-05"},0.217,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["VPS51","Glasdegib",0.421,0.036,-0.768,0.000517,-4.18,{"v":2.87E-5,"d":"2.87E-05"},{"v":7.39e-05,"d":"7.39E-05"},0.217,"+/-","Smo inhibitor","SMO","Hedgehog inhibitor"]
["TOPORS","Bleomycin",0.547,0.00463,-0.689,3.13E-3,-4.18,{"v":2.95e-05,"d":"2.95E-05"},{"v":7.41e-05,"d":"7.41E-05"},0.217,"+/-","Glycopeptide antibiotic, causes DNA breaks","DNA","Conv.Chemo"]
["ANKS6","Vistusertib",0.415,0.0392,-0.692,2.96E-3,-3.7,0.000217,0.000356,0.218,"+/-","mTOR inhibitor, ATP-competitive","MTOR","Kinase inhibitor"]
["ATIC","Pemetrexed",0.41,0.0416,-0.695,2.81E-3,-3.7,0.000218,0.000356,0.218,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["CAMKMT","A_1331852",-0.477,0.0159,0.649,0.00649,3.7,0.000218,3.57E-4,0.218,"-/+","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2;MCL1","Apoptotic modulator"]
["ATF2","Tamatinib",-0.511,0.00898,0.622,0.0101,3.7,0.00022,0.000358,0.218,"-/+","SYK inhibitor","SYK","Kinase inhibitor"]
["ARID3B","Dasatinib",-0.17,0.416,0.808,1.54E-4,3.69,0.00022,0.000358,0.218,"0/+","ABL, Src, Kit, EphR Inhibitor","ABL1","Kinase inhibitor"]
["EIF4B","Cabazitaxel",0.408,0.0431,-0.784,3.21E-4,-4.26,{"v":2.06e-05,"d":"2.06E-05"},{"v":7e-05,"d":"7.00E-05"},0.218,"+/-","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["SLC35B2","LY3023414",-0.592,1.82E-3,0.637,0.0079,4.1,{"v":4.11e-05,"d":"4.11E-05"},1.06E-4,0.218,"-/+","PI3K, mTOR, DNA-PK inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;PRKDC","Kinase inhibitor"]
["TMEM268","LY3009120",0.315,0.125,-0.803,0.000178,-4.1,{"v":4.16e-05,"d":"4.16E-05"},1.07E-4,0.218,"0/-","Pan-RAF, (Pan-HER inhibitor)","BRAF;RAF1","Kinase inhibitor"]
["TBC1D10C","Cytarabine",-0.429,0.0322,0.751,0.000807,4.1,{"v":4.17e-05,"d":"4.17E-05"},1.08E-4,0.218,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ATE1","GSK_2334470",-0.617,0.00102,0.517,0.0403,3.69,0.00022,0.00036,0.219,"-/+","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["C8orf82","AZD3965",-0.194,0.352,0.799,0.000207,3.69,2.22E-4,0.000361,0.219,"0/+","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["C10orf88","Talazoparib",0.28,0.175,-0.763,0.000587,-3.69,2.24E-4,0.000361,0.219,"0/-","PARP1 and 2 inhibitor","PARP1;PARP2","Differentiating.epigenetic modifier"]
["ASB6","AT9283",0.251,0.227,-0.776,0.000412,-3.69,2.24E-4,0.000362,0.219,"0/-","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["IMPA1","LY_2584702",0.283,0.17,-0.851,{"v":2.96e-05,"d":"2.96E-05"},-4.43,{"v":9.42e-06,"d":"9.42E-06"},{"v":3.84e-05,"d":"3.84E-05"},0.219,"0/-","p70S6K inhibitor","RPS6KB1","Kinase inhibitor"]
["MIGA1","BMS_754807",0.371,0.0675,-0.819,1.03E-4,-4.42,{"v":1.01E-5,"d":"1.01E-05"},{"v":4.14e-05,"d":"4.14E-05"},0.219,"0/-","IGF1R inhibitor","IGF1R","Kinase inhibitor"]
["ICAM1","8_amino_adenosine",-0.511,0.00908,0.753,0.000753,4.41,{"v":1.01E-5,"d":"1.01E-05"},{"v":4.14e-05,"d":"4.14E-05"},0.219,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["LRR1","Cytarabine.Idarubicin",0.555,3.96E-3,-0.725,1.48E-3,-4.41,{"v":1.01E-5,"d":"1.01E-05"},{"v":4.14e-05,"d":"4.14E-05"},0.219,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["MED27","Ganetespib",0.519,7.79E-3,-0.747,0.000889,-4.41,{"v":1.06E-5,"d":"1.06E-05"},{"v":4.29e-05,"d":"4.29E-05"},0.219,"+/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["MCPH1","Prexasertib",0.645,{"v":0.0005,"d":"5.00E-04"},-0.646,0.00689,-4.39,{"v":1.15E-5,"d":"1.15E-05"},{"v":4.66e-05,"d":"4.66E-05"},0.219,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["KIFC1","Olaparib",0.834,{"v":2.17E-7,"d":"2.17E-07"},-0.319,0.229,-4.38,{"v":1.18e-05,"d":"1.18E-05"},{"v":4.76e-05,"d":"4.76E-05"},0.219,"+/0","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["LRRC40","ARV_825",-0.646,0.000481,0.643,0.0072,4.38,{"v":1.18e-05,"d":"1.18E-05"},{"v":4.76e-05,"d":"4.76E-05"},0.219,"-/+","BET-targeting PROTAC","BRD4","Differentiating.epigenetic modifier"]
["MCTP2","Oprozomib",-0.111,0.599,0.89,{"v":3.92e-06,"d":"3.92E-06"},4.38,{"v":1.19E-5,"d":"1.19E-05"},{"v":4.81e-05,"d":"4.81E-05"},0.219,"0/+","proteasome (20 S) inhibitor","PSMB5;PSMB8","Protease.proteasome inhibitor"]
["KIF14","Cytarabine",0.756,{"v":1.26E-5,"d":"1.26E-05"},-0.497,0.0502,-4.38,{"v":1.21e-05,"d":"1.21E-05"},{"v":4.88E-5,"d":"4.88E-05"},0.219,"+/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["KIF11","Cytarabine",0.795,{"v":2.08E-6,"d":"2.08E-06"},-0.418,0.107,-4.37,{"v":1.23e-05,"d":"1.23E-05"},{"v":4.91e-05,"d":"4.91E-05"},0.219,"+/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["MAN2B2","Cisplatin",-0.411,0.0413,0.797,0.000219,4.36,{"v":1.27E-5,"d":"1.27E-05"},{"v":5.03e-05,"d":"5.03E-05"},0.219,"-/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["LXN","Onalespib",-0.562,3.46E-3,0.712,1.98E-3,4.36,{"v":1.28e-05,"d":"1.28E-05"},{"v":5.03e-05,"d":"5.03E-05"},0.219,"-/+","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["MCRIP1","MK_8745",0.546,0.00476,-0.722,0.00159,-4.36,{"v":1.32e-05,"d":"1.32E-05"},{"v":5.18e-05,"d":"5.18E-05"},0.219,"+/-","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["KNSTRN","Gemcitabine",0.613,0.00111,-0.669,4.64E-3,-4.35,{"v":1.35e-05,"d":"1.35E-05"},{"v":5.31e-05,"d":"5.31E-05"},0.219,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["KCTD3","Dasatinib",0.355,0.0818,-0.816,1.17E-4,-4.33,{"v":1.49E-5,"d":"1.49E-05"},{"v":5.81e-05,"d":"5.81E-05"},0.219,"0/-","ABL, Src, Kit, EphR Inhibitor","ABL1","Kinase inhibitor"]
["KNSTRN","Raltitrexed",0.785,{"v":3.36E-6,"d":"3.36E-06"},-0.424,0.101,-4.32,{"v":1.56E-5,"d":"1.56E-05"},{"v":6.03e-05,"d":"6.03E-05"},0.219,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["IDH3B","Sunitinib",0.64,0.000576,-0.637,0.00799,-4.32,{"v":1.58e-05,"d":"1.58E-05"},{"v":6.11e-05,"d":"6.11E-05"},0.219,"+/-","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["KLF6","Digoxin",0.437,0.029,-0.779,0.00038,-4.32,{"v":1.58e-05,"d":"1.58E-05"},{"v":6.11e-05,"d":"6.11E-05"},0.219,"+/-","Cardiac glycoside","ATP1A1;ITGB1;ITGB3;ITGA3;ITGA1","Other"]
["LGALS3BP","SN_38",-0.246,0.236,0.851,{"v":2.95e-05,"d":"2.95E-05"},4.32,{"v":1.58e-05,"d":"1.58E-05"},{"v":6.11e-05,"d":"6.11E-05"},0.219,"0/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["MICAL3","GSK2256098",0.336,0.1,-0.821,{"v":9.71e-05,"d":"9.71E-05"},-4.31,{"v":1.6e-05,"d":"1.60E-05"},{"v":6.13e-05,"d":"6.13E-05"},0.219,"0/-","FAK inhibitor","PTK2","Kinase inhibitor"]
["KIF20B","RGFP966",0.827,{"v":3.45e-07,"d":"3.45E-07"},-0.318,0.23,-4.31,{"v":1.62e-05,"d":"1.62E-05"},{"v":6.21e-05,"d":"6.21E-05"},0.219,"+/0","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["LDAH","Imiquimod",0.0144,0.945,-0.904,{"v":1.58e-06,"d":"1.58E-06"},-4.31,{"v":1.65e-05,"d":"1.65E-05"},{"v":6.23e-05,"d":"6.23E-05"},0.219,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["MED12L","Vismodegib",0.156,0.455,-0.874,{"v":9.71e-06,"d":"9.71E-06"},-4.31,{"v":1.65e-05,"d":"1.65E-05"},{"v":6.23e-05,"d":"6.23E-05"},0.219,"0/-","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["MAGED1","BIIB021",0.451,0.0237,-0.77,0.000483,-4.31,{"v":1.66E-5,"d":"1.66E-05"},{"v":6.25e-05,"d":"6.25E-05"},0.219,"+/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["MICU2","Everolimus",-0.413,0.04,0.788,0.000291,4.3,{"v":1.69e-05,"d":"1.69E-05"},{"v":6.33e-05,"d":"6.33E-05"},0.219,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["KNSTRN","SN_38",0.547,0.00469,-0.712,1.98E-3,-4.3,{"v":1.7E-5,"d":"1.70E-05"},{"v":6.33e-05,"d":"6.33E-05"},0.219,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["LARP1B","RGFP966",0.663,0.000304,-0.608,0.0125,-4.3,{"v":1.72e-05,"d":"1.72E-05"},{"v":6.5e-05,"d":"6.50E-05"},0.219,"+/-","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["MKRN2","Imiquimod",0.358,0.0787,-0.811,0.00014,-4.3,{"v":1.72e-05,"d":"1.72E-05"},{"v":6.5e-05,"d":"6.50E-05"},0.219,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["MBOAT7","Cytarabine",-0.783,{"v":3.66e-06,"d":"3.66E-06"},0.421,0.104,4.3,{"v":1.73E-5,"d":"1.73E-05"},{"v":6.53e-05,"d":"6.53E-05"},0.219,"-/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["METTL17","Abexinostat",-0.705,{"v":8.23e-05,"d":"8.23E-05"},0.551,0.0271,4.28,{"v":1.87e-05,"d":"1.87E-05"},{"v":6.98e-05,"d":"6.98E-05"},0.219,"-/+","HDAC1 selective inhibitor","HDAC1","Differentiating.epigenetic modifier"]
["MCM10","Cytarabine.Idarubicin",0.654,0.000392,-0.614,0.0115,-4.28,{"v":1.88E-5,"d":"1.88E-05"},{"v":6.98e-05,"d":"6.98E-05"},0.219,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["MIS18A","SN_38",0.528,0.00667,-0.721,0.00163,-4.28,{"v":1.89e-05,"d":"1.89E-05"},{"v":6.98e-05,"d":"6.98E-05"},0.219,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["MED30","Capmatinib",-0.93,{"v":1.67e-11,"d":"1.67E-11"},-0.165,0.543,4.27,{"v":1.92e-05,"d":"1.92E-05"},{"v":6.98e-05,"d":"6.98E-05"},0.219,"-/0","MET inhibitor","MET","Kinase inhibitor"]
["MICU1","Everolimus",-0.431,0.0314,0.775,0.000422,4.27,{"v":1.95E-5,"d":"1.95E-05"},{"v":7.05e-05,"d":"7.05E-05"},0.219,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["IDH3B","Merestinib",0.625,0.000832,-0.641,0.00742,-4.27,{"v":1.95E-5,"d":"1.95E-05"},{"v":7.05e-05,"d":"7.05E-05"},0.219,"+/-","MET inhibitor","MET","Kinase inhibitor"]
["LARS2","Losmapimod",0.375,0.0647,-0.8,0.000197,-4.27,{"v":1.96e-05,"d":"1.96E-05"},{"v":7.1e-05,"d":"7.10E-05"},0.219,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["MED30","Tasquinimod",-0.906,{"v":4.53e-10,"d":"4.53E-10"},-0.0138,0.96,4.27,{"v":1.99e-05,"d":"1.99E-05"},{"v":7.2e-05,"d":"7.20E-05"},0.219,"-/0","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["KIF20B","Cytarabine",0.727,{"v":3.83e-05,"d":"3.83E-05"},-0.515,0.0413,-4.26,{"v":2e-05,"d":"2.00E-05"},{"v":7.23e-05,"d":"7.23E-05"},0.219,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["MIS18A","Carboplatin",0.515,0.00837,-0.726,0.00145,-4.26,{"v":2.04e-05,"d":"2.04E-05"},{"v":7.28e-05,"d":"7.28E-05"},0.219,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["KCNAB2","Cytarabine",-0.754,{"v":1.36E-5,"d":"1.36E-05"},0.467,0.0681,4.25,{"v":2.1e-05,"d":"2.10E-05"},{"v":7.53e-05,"d":"7.53E-05"},0.219,"-/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["LSM1","Sitravatinib",-0.294,0.154,0.828,{"v":7.34e-05,"d":"7.34E-05"},4.25,{"v":2.16E-5,"d":"2.16E-05"},{"v":7.7e-05,"d":"7.70E-05"},0.219,"0/+","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["IFNAR1","Alisertib",-0.691,0.00013,0.562,0.0236,4.25,{"v":2.17e-05,"d":"2.17E-05"},{"v":7.7e-05,"d":"7.70E-05"},0.219,"-/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["KLHDC4","Ivosidenib",-0.765,{"v":8.28e-06,"d":"8.28E-06"},0.442,0.0864,4.24,{"v":2.21e-05,"d":"2.21E-05"},{"v":7.75E-5,"d":"7.75E-05"},0.219,"-/0","IDH1 R132H and R132C inhibitor","IDH1","Differentiating.epigenetic modifier"]
["LCP2","Cytarabine",-0.305,0.139,0.824,{"v":8.71e-05,"d":"8.71E-05"},4.24,{"v":2.23E-5,"d":"2.23E-05"},{"v":7.78e-05,"d":"7.78E-05"},0.219,"0/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["LY86","A_1155463",0.491,0.0127,-0.737,0.00112,-4.24,{"v":2.27E-5,"d":"2.27E-05"},{"v":7.95e-05,"d":"7.95E-05"},0.219,"+/-","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2","Apoptotic modulator"]
["MAP3K3","Triapine",-0.618,0.000987,0.64,0.00754,4.23,{"v":2.3E-5,"d":"2.30E-05"},{"v":8.07e-05,"d":"8.07E-05"},0.219,"-/+","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["METTL17","AR_42",-0.759,{"v":1.07e-05,"d":"1.07E-05"},0.451,0.0796,4.23,{"v":2.31e-05,"d":"2.31E-05"},{"v":8.12e-05,"d":"8.12E-05"},0.219,"-/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["MAPK7","Fostamatinib",-0.314,0.126,0.819,1.02E-4,4.23,{"v":2.32e-05,"d":"2.32E-05"},{"v":8.15e-05,"d":"8.15E-05"},0.219,"0/+","SYK inhibitor","SYK","Kinase inhibitor"]
["KNSTRN","Topotecan",0.413,0.04,-0.778,3.86E-4,-4.23,{"v":2.33e-05,"d":"2.33E-05"},{"v":8.15e-05,"d":"8.15E-05"},0.219,"+/-","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["MBOAT7","Pemetrexed",-0.676,0.000206,0.577,0.0194,4.23,{"v":2.34E-5,"d":"2.34E-05"},{"v":8.25E-5,"d":"8.25E-05"},0.219,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["ITGA2","Tasquinimod",-0.135,0.521,0.873,{"v":1.04E-5,"d":"1.04E-05"},4.23,{"v":2.35e-05,"d":"2.35E-05"},{"v":8.3e-05,"d":"8.30E-05"},0.219,"0/+","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["KIDINS220","Clofarabine",0.523,0.00731,-0.716,1.82E-3,-4.23,{"v":2.35e-05,"d":"2.35E-05"},{"v":8.35e-05,"d":"8.35E-05"},0.219,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["IRS1","Prexasertib",0.447,0.0252,-0.76,0.000626,-4.23,{"v":2.39e-05,"d":"2.39E-05"},{"v":8.45e-05,"d":"8.45E-05"},0.219,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ICE1","Tozasertib",0.297,0.149,-0.825,{"v":8.46e-05,"d":"8.46E-05"},-4.22,{"v":2.39e-05,"d":"2.39E-05"},{"v":8.45e-05,"d":"8.45E-05"},0.219,"0/-","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["INCENP","Cytarabine",0.679,0.00019,-0.572,0.0207,-4.22,{"v":2.42e-05,"d":"2.42E-05"},{"v":8.47e-05,"d":"8.47E-05"},0.219,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ITPR3","Sitravatinib",-0.688,0.000142,0.559,0.0243,4.22,{"v":2.43e-05,"d":"2.43E-05"},{"v":8.47e-05,"d":"8.47E-05"},0.219,"-/+","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["MCM10","Prexasertib",0.705,{"v":8.25E-5,"d":"8.25E-05"},-0.535,0.0326,-4.22,{"v":2.47e-05,"d":"2.47E-05"},{"v":8.5e-05,"d":"8.50E-05"},0.219,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["KNSTRN","Prexasertib",0.747,{"v":1.79e-05,"d":"1.79E-05"},-0.469,0.0669,-4.22,{"v":2.48E-5,"d":"2.48E-05"},{"v":8.52e-05,"d":"8.52E-05"},0.219,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ICE1","Ridaforolimus",0.469,0.0181,-0.747,0.000886,-4.21,{"v":2.5e-05,"d":"2.50E-05"},{"v":8.55e-05,"d":"8.55E-05"},0.219,"+/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["MED30","EPZ015666",-0.91,{"v":2.96e-10,"d":"2.96E-10"},-0.0518,0.849,4.21,{"v":2.5e-05,"d":"2.50E-05"},{"v":8.55e-05,"d":"8.55E-05"},0.219,"-/0","PRMT5 inhibitor","PRMT5","Differentiating.epigenetic modifier"]
["LARS1","AT9283",0.369,0.0697,-0.796,0.000226,-4.21,{"v":2.51E-5,"d":"2.51E-05"},{"v":8.55e-05,"d":"8.55E-05"},0.219,"0/-","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["LAMTOR4","Milciclib",-0.263,0.204,0.835,{"v":5.67e-05,"d":"5.67E-05"},4.21,{"v":2.51E-5,"d":"2.51E-05"},{"v":8.55e-05,"d":"8.55E-05"},0.219,"0/+","CDK2 inhibitor","CDK2;CDK4;CDK5;CDK7;NTRK1","Kinase inhibitor"]
["IPP","Vinblastine",0.51,0.00927,-0.722,0.00159,-4.21,{"v":2.52e-05,"d":"2.52E-05"},{"v":8.55e-05,"d":"8.55E-05"},0.219,"+/-","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["MCM10","Gemcitabine",0.501,0.0108,-0.727,0.00143,-4.21,{"v":2.57e-05,"d":"2.57E-05"},{"v":8.67e-05,"d":"8.67E-05"},0.219,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["KNL1","Cytarabine",0.752,{"v":1.45E-5,"d":"1.45E-05"},-0.457,0.0749,-4.21,{"v":2.58E-5,"d":"2.58E-05"},{"v":8.67e-05,"d":"8.67E-05"},0.219,"+/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["KLC2","AT_406",-0.497,0.0115,0.729,0.00137,4.21,{"v":2.61e-05,"d":"2.61E-05"},{"v":8.67e-05,"d":"8.67E-05"},0.219,"-/+","XIAP, cIAP1, cIAP2 inhibitor","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["MPV17","Erlotinib",-0.462,0.0199,0.749,0.000847,4.2,{"v":2.63e-05,"d":"2.63E-05"},{"v":8.72e-05,"d":"8.72E-05"},0.219,"-/+","EGFR inhibitor","EGFR","Kinase inhibitor"]
["MORF4L2","Imiquimod",-0.143,0.496,0.868,{"v":1.28e-05,"d":"1.28E-05"},4.2,{"v":2.63e-05,"d":"2.63E-05"},{"v":8.75e-05,"d":"8.75E-05"},0.219,"0/+","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["LRR1","Gemcitabine",0.426,0.0337,-0.767,0.00052,-4.2,{"v":2.68e-05,"d":"2.68E-05"},{"v":8.87e-05,"d":"8.87E-05"},0.219,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["KRT4","AZD3965",-0.263,0.203,0.833,{"v":6.08e-05,"d":"6.08E-05"},4.2,{"v":2.68e-05,"d":"2.68E-05"},{"v":8.87e-05,"d":"8.87E-05"},0.219,"0/+","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["MROH1","Tozasertib",-0.535,0.00588,0.702,0.00242,4.2,{"v":2.69E-5,"d":"2.69E-05"},{"v":8.87e-05,"d":"8.87E-05"},0.219,"-/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["ISOC1","Tivantinib",0.175,0.404,-0.859,{"v":2.07e-05,"d":"2.07E-05"},-4.19,{"v":2.84e-05,"d":"2.84E-05"},{"v":9.22e-05,"d":"9.22E-05"},0.219,"0/-","MET inhibitor","MET","Kinase inhibitor"]
["IP6K2","Abexinostat",0.613,0.00112,-0.635,0.00816,-4.19,{"v":2.85e-05,"d":"2.85E-05"},{"v":9.27e-05,"d":"9.27E-05"},0.219,"+/-","HDAC1 selective inhibitor","HDAC1","Differentiating.epigenetic modifier"]
["LRFN4","Losmapimod",0.164,0.434,-0.861,{"v":1.84E-5,"d":"1.84E-05"},-4.18,{"v":2.9E-5,"d":"2.90E-05"},{"v":9.35e-05,"d":"9.35E-05"},0.219,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["LARS1","BX_912",0.439,0.028,-0.758,0.00067,-4.18,{"v":2.9E-5,"d":"2.90E-05"},{"v":9.35e-05,"d":"9.35E-05"},0.219,"+/-","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["IFI30","VER_155008",-0.429,0.0322,0.762,0.000598,4.18,{"v":2.98e-05,"d":"2.98E-05"},{"v":9.44e-05,"d":"9.44E-05"},0.219,"-/+","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["ISOC1","Axitinib",0.231,0.266,-0.841,{"v":4.49E-5,"d":"4.49E-05"},-4.17,{"v":3e-05,"d":"3.00E-05"},{"v":9.47e-05,"d":"9.47E-05"},0.219,"0/-","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["MIER2","Imiquimod",0.257,0.215,-0.833,{"v":6.25e-05,"d":"6.25E-05"},-4.17,{"v":3.01E-5,"d":"3.01E-05"},{"v":9.49e-05,"d":"9.49E-05"},0.219,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["KIF14","Prexasertib",0.729,{"v":3.62e-05,"d":"3.62E-05"},-0.488,0.055,-4.17,{"v":3.02e-05,"d":"3.02E-05"},{"v":9.52e-05,"d":"9.52E-05"},0.219,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ISOC1","TAK_901",0.365,0.0725,-0.792,0.000256,-4.17,{"v":3.02e-05,"d":"3.02E-05"},{"v":9.52e-05,"d":"9.52E-05"},0.219,"0/-","Aurora, Src family, JAK3, RTK inhibitor","AURKA;AURKB;JAK3;SRC;CLK2;FGR;LRRK2;YES1;LCK;FYN;ABL1;AXL;ABL2;HCK;RET;FRK;NTRK1;FGFR2","Kinase inhibitor"]
["METTL2B","Pemetrexed",0.695,1.15E-4,-0.537,0.0318,-4.17,{"v":3.06e-05,"d":"3.06E-05"},{"v":9.62e-05,"d":"9.62E-05"},0.219,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["MRFAP1","VER_155008",0.74,{"v":2.33e-05,"d":"2.33E-05"},-0.467,0.0684,-4.16,{"v":3.11e-05,"d":"3.11E-05"},{"v":9.64e-05,"d":"9.64E-05"},0.219,"+/0","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["LARS1","Tozasertib",0.494,0.012,-0.723,1.56E-3,-4.16,{"v":3.18E-5,"d":"3.18E-05"},{"v":9.77e-05,"d":"9.77E-05"},0.219,"+/-","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["MAVS","Prexasertib",-0.723,{"v":4.45e-05,"d":"4.45E-05"},0.494,0.0519,4.16,{"v":3.2e-05,"d":"3.20E-05"},{"v":9.79e-05,"d":"9.79E-05"},0.219,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["JADE3","Carboplatin",0.325,0.112,-0.806,0.000161,-4.16,{"v":3.22e-05,"d":"3.22E-05"},{"v":9.84e-05,"d":"9.84E-05"},0.219,"0/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["KIF4A","Cytarabine",0.557,0.00386,-0.678,0.00387,-4.16,{"v":3.23e-05,"d":"3.23E-05"},{"v":9.84e-05,"d":"9.84E-05"},0.219,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["KAT6A","Sorafenib",-0.86,{"v":3.74e-08,"d":"3.74E-08"},0.16,0.554,4.15,{"v":3.28e-05,"d":"3.28E-05"},{"v":9.94e-05,"d":"9.94E-05"},0.219,"-/0","BRAF, FGFR-1, VEGFR-2 and -3, PDGFR-beta, KIT, and FLT3 inhibitor","BRAF;FGFR1;KDR;FLT3;KIT;FLT4;PDGFRB","Kinase inhibitor"]
["LCOR","VER_155008",0.584,2.16E-3,-0.655,0.0059,-4.15,{"v":3.28e-05,"d":"3.28E-05"},{"v":9.94e-05,"d":"9.94E-05"},0.219,"+/-","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["KLHL24","AZD3965",-0.41,0.0416,0.769,0.000505,4.15,{"v":3.29E-5,"d":"3.29E-05"},{"v":9.97e-05,"d":"9.97E-05"},0.219,"-/+","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["IDH3A","Cabozantinib",0.284,0.169,-0.821,{"v":9.83e-05,"d":"9.83E-05"},-4.15,{"v":3.36e-05,"d":"3.36E-05"},1.01E-4,0.219,"0/-","VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor","KDR;MET;FLT3;KIT;RET;TEK","Kinase inhibitor"]
["MIEF1","Daporinad",0.519,0.0079,-0.705,2.31E-3,-4.15,{"v":3.37e-05,"d":"3.37E-05"},1.02E-4,0.219,"+/-","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["MIS18A","Pemetrexed",0.538,0.00554,-0.691,0.00306,-4.15,{"v":3.39e-05,"d":"3.39E-05"},1.03E-4,0.219,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["KIF20B","SN_38",0.718,{"v":5.29e-05,"d":"5.29E-05"},-0.498,0.0497,-4.15,{"v":3.39e-05,"d":"3.39E-05"},1.03E-4,0.219,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["MORF4L2","Perifosine",-0.299,0.146,0.814,1.22E-4,4.14,{"v":3.44e-05,"d":"3.44E-05"},0.000104,0.219,"0/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["KIF4A","Prexasertib",0.676,0.000211,-0.557,0.0251,-4.14,{"v":3.44e-05,"d":"3.44E-05"},0.000104,0.219,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["KCNAB2","Decitabine",-0.477,0.016,0.731,0.0013,4.14,{"v":3.44e-05,"d":"3.44E-05"},0.000104,0.219,"-/+","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["MIS18A","Etoposide",0.295,0.152,-0.816,1.17E-4,-4.14,{"v":3.5e-05,"d":"3.50E-05"},1.05E-4,0.219,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["MANBA","VER_155008",-0.528,6.62E-3,0.696,0.00276,4.14,{"v":3.52e-05,"d":"3.52E-05"},1.06E-4,0.219,"-/+","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["MICU2","Ridaforolimus",-0.453,0.0231,0.744,0.000954,4.14,{"v":3.53e-05,"d":"3.53E-05"},1.06E-4,0.219,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["MICU1","Temsirolimus",-0.382,0.0593,0.779,0.000372,4.13,{"v":3.55e-05,"d":"3.55E-05"},1.06E-4,0.219,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["LAX1","Trifluridine",-0.642,0.000534,0.594,0.0152,4.13,{"v":3.55e-05,"d":"3.55E-05"},1.06E-4,0.219,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["METTL9","Enzalutamide",-0.241,0.245,0.834,{"v":6.02E-5,"d":"6.02E-05"},4.13,{"v":3.56e-05,"d":"3.56E-05"},1.06E-4,0.219,"0/+","AR antagonist","AR","Hormone therapy"]
["LAMTOR2","Daporinad",-0.689,0.000138,0.537,0.0321,4.13,{"v":3.56e-05,"d":"3.56E-05"},1.06E-4,0.219,"-/+","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["MCM10","OSU_03012",0.694,1.2E-4,-0.53,0.0347,-4.13,{"v":3.59e-05,"d":"3.59E-05"},1.07E-4,0.219,"+/-","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["KIF11","Prexasertib",0.753,{"v":1.4E-5,"d":"1.40E-05"},-0.434,0.0928,-4.13,{"v":3.61e-05,"d":"3.61E-05"},1.07E-4,0.219,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["MICU1","Pevonedistat",-0.4,0.0477,0.771,0.000477,4.13,{"v":3.61e-05,"d":"3.61E-05"},1.07E-4,0.219,"-/+","NAE inhibitor","NAE1","Metabolic modifier"]
["ISOC2","RGFP966",-0.698,1.03E-4,0.523,0.0377,4.13,{"v":3.64e-05,"d":"3.64E-05"},1.08E-4,0.219,"-/+","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["KLC2","NVP_LCL161",-0.267,0.196,0.824,{"v":8.59e-05,"d":"8.59E-05"},4.13,{"v":3.66e-05,"d":"3.66E-05"},0.000109,0.219,"0/+","IAPs, SMAC mimetic","XIAP;BIRC2","Apoptotic modulator"]
["LRR1","Etoposide",0.512,0.00888,-0.705,0.00228,-4.12,{"v":3.71e-05,"d":"3.71E-05"},0.000109,0.219,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["MFSD10","Tasquinimod",-0.638,0.000605,0.596,0.0147,4.12,{"v":3.76e-05,"d":"3.76E-05"},1.1E-4,0.219,"-/+","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["LIMK2","Cisplatin",-0.424,0.0347,0.757,0.000685,4.12,{"v":3.78e-05,"d":"3.78E-05"},1.1E-4,0.219,"-/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["MON2","GSK269962",-0.281,0.174,0.818,1.06E-4,4.12,{"v":3.82E-5,"d":"3.82E-05"},1.1E-4,0.219,"0/+","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["ILVBL","Vorinostat",-0.488,0.0134,0.719,0.00168,4.11,{"v":3.89e-05,"d":"3.89E-05"},1.12E-4,0.219,"-/+","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["MIS18A","Topotecan",0.487,0.0135,-0.72,1.67E-3,-4.11,{"v":3.9e-05,"d":"3.90E-05"},1.12E-4,0.219,"+/-","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["KCTD15","Binimetinib",-0.273,0.186,0.82,{"v":9.9e-05,"d":"9.90E-05"},4.11,{"v":3.91e-05,"d":"3.91E-05"},1.13E-4,0.219,"0/+","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["MBOAT7","Everolimus",-0.524,0.00715,0.694,0.00284,4.11,{"v":3.93E-5,"d":"3.93E-05"},1.13E-4,0.219,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["MAPKAPK3","Cytarabine",-0.731,{"v":3.34e-05,"d":"3.34E-05"},0.467,0.0681,4.11,{"v":4e-05,"d":"4.00E-05"},0.000114,0.219,"-/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["MLLT11","AZD8055",0.625,0.000833,-0.607,0.0127,-4.11,{"v":4e-05,"d":"4.00E-05"},0.000114,0.219,"+/-","mTOR inhibitor","MTOR","Kinase inhibitor"]
["ILVBL","Docetaxel",-0.283,0.171,0.816,1.15E-4,4.1,{"v":4.04e-05,"d":"4.04E-05"},1.15E-4,0.219,"0/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["L2HGDH","Gandotinib",-0.454,0.0226,0.738,0.0011,4.1,{"v":4.06e-05,"d":"4.06E-05"},1.15E-4,0.219,"-/+","JAK2 inhibitor","JAK2;JAK1;FLT3;FLT4;FGFR2;TYK2;NTRK2;FGFR3;KDR;ALK","Kinase inhibitor"]
["ICE1","Docetaxel",0.349,0.087,-0.79,0.000273,-4.1,{"v":4.07E-5,"d":"4.07E-05"},1.15E-4,0.219,"0/-","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["INIP","Brigatinib",-0.112,0.594,0.867,{"v":1.35e-05,"d":"1.35E-05"},4.1,{"v":4.08e-05,"d":"4.08E-05"},1.15E-4,0.219,"0/+","ALK inhibitor, including gatekeeper mutant ALK","ALK;ROS1;IGF1R;EGFR;INSR;ABL1;FLT3;MET;ERBB2;ERBB4","Kinase inhibitor"]
["KNSTRN","Cytarabine.Idarubicin",0.625,0.000842,-0.605,0.013,-4.1,{"v":4.14e-05,"d":"4.14E-05"},1.16E-4,0.219,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["IFT46","MST_312",0.166,0.429,-0.853,{"v":2.69E-5,"d":"2.69E-05"},-4.1,{"v":4.16e-05,"d":"4.16E-05"},1.16E-4,0.219,"0/-","Telomerase inhibitor","TERT","Other"]
["METTL21A","Methotrexate",0.447,0.025,-0.74,0.00104,-4.1,{"v":4.22e-05,"d":"4.22E-05"},1.17E-4,0.219,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["LRRC42","Itraconazole",-0.156,0.457,0.855,{"v":2.42e-05,"d":"2.42E-05"},4.09,{"v":4.23e-05,"d":"4.23E-05"},1.17E-4,0.219,"0/+","antifungal, hedgehog signaling inhibitor","CYP51A1;CYP3A4","Other"]
["KPNA1","Olaparib",0.171,0.413,-0.851,{"v":2.95e-05,"d":"2.95E-05"},-4.09,{"v":4.26e-05,"d":"4.26E-05"},1.18E-4,0.219,"0/-","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["KAT6B","Azacitidine",-0.483,0.0144,0.718,1.72E-3,4.09,{"v":4.27e-05,"d":"4.27E-05"},1.18E-4,0.219,"-/+","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["MRPL9","Quizartinib",0.606,1.32E-3,-0.622,0.0101,-4.09,{"v":4.29e-05,"d":"4.29E-05"},0.000119,0.219,"+/-","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["PET100","Azacitidine",0.39,0.0539,-0.82,{"v":1E-4,"d":"1.00E-04"},-4.49,{"v":7.29e-06,"d":"7.29E-06"},{"v":3.56e-05,"d":"3.56E-05"},0.219,"0/-","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["PBK","Cytarabine.Idarubicin",0.758,{"v":1.15E-5,"d":"1.15E-05"},-0.52,0.039,-4.48,{"v":7.48e-06,"d":"7.48E-06"},{"v":3.56e-05,"d":"3.56E-05"},0.219,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["NDRG1","Cytarabine.Idarubicin",-0.659,0.000341,0.648,0.00663,4.47,{"v":7.9e-06,"d":"7.90E-06"},{"v":3.86e-05,"d":"3.86E-05"},0.219,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["PIK3CD","Cerdulatinib",-0.277,0.18,0.856,{"v":2.33e-05,"d":"2.33E-05"},4.47,{"v":7.95e-06,"d":"7.95E-06"},{"v":3.86e-05,"d":"3.86E-05"},0.219,"0/+","JAK, SYK inhibitor","JAK1;JAK2;JAK3;TYK2;SYK","Kinase inhibitor"]
["OIP5","Topotecan",0.517,0.0081,-0.756,0.000701,-4.46,{"v":8.25e-06,"d":"8.25E-06"},{"v":3.86e-05,"d":"3.86E-05"},0.219,"+/-","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["PIK3AP1","Ribociclib",-0.508,0.00952,0.761,0.000621,4.45,{"v":8.41e-06,"d":"8.41E-06"},{"v":3.99e-05,"d":"3.99E-05"},0.219,"-/+","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["PFDN5","Axitinib",0.553,0.00412,-0.729,0.00135,-4.43,{"v":9.39e-06,"d":"9.39E-06"},{"v":4.26e-05,"d":"4.26E-05"},0.219,"+/-","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["NSL1","S_63845",0.536,0.00571,-0.739,1.07E-3,-4.42,{"v":9.65e-06,"d":"9.65E-06"},{"v":4.26e-05,"d":"4.26E-05"},0.219,"+/-","MCL-1 inhibitor","MCL1","Apoptotic modulator"]
["PFDN6","Tozasertib",0.434,0.0302,-0.794,2.42E-4,-4.42,{"v":9.89e-06,"d":"9.89E-06"},{"v":4.34e-05,"d":"4.34E-05"},0.219,"+/-","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["PLD3","I_BET151",-0.238,0.252,0.863,{"v":1.71e-05,"d":"1.71E-05"},4.42,{"v":9.89e-06,"d":"9.89E-06"},{"v":4.34e-05,"d":"4.34E-05"},0.219,"0/+","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["MTMR14","Clofarabine",-0.456,0.0219,0.782,0.000342,4.41,{"v":1.02e-05,"d":"1.02E-05"},{"v":4.41e-05,"d":"4.41E-05"},0.219,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["POLK","AZD8055",-0.367,0.0709,0.82,{"v":9.93e-05,"d":"9.93E-05"},4.41,{"v":1.03E-5,"d":"1.03E-05"},{"v":4.49E-5,"d":"4.49E-05"},0.219,"0/+","mTOR inhibitor","MTOR","Kinase inhibitor"]
["NDRG1","OTS167",-0.503,0.0103,0.756,6.96E-4,4.41,{"v":1.05e-05,"d":"1.05E-05"},{"v":4.59e-05,"d":"4.59E-05"},0.219,"-/+","MELK inhibitor","MELK","Kinase inhibitor"]
["PM20D2","Givinostat",-0.75,{"v":1.58e-05,"d":"1.58E-05"},0.507,0.0449,4.38,{"v":1.19E-5,"d":"1.19E-05"},{"v":4.81e-05,"d":"4.81E-05"},0.219,"-/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC10","Differentiating.epigenetic modifier"]
["PLA2G4A","Merestinib",0.814,{"v":7.4e-07,"d":"7.40E-07"},-0.373,0.155,-4.38,{"v":1.21e-05,"d":"1.21E-05"},{"v":4.83e-05,"d":"4.83E-05"},0.219,"+/0","MET inhibitor","MET","Kinase inhibitor"]
["NUCB1","Hydroxyurea",-0.411,0.0413,0.798,0.00021,4.37,{"v":1.22E-5,"d":"1.22E-05"},{"v":4.83e-05,"d":"4.83E-05"},0.219,"-/+","Antineoplastic agent","RRM1","Conv.Chemo"]
["PLEKHA8","Vinblastine",0.498,0.0113,-0.754,0.000732,-4.37,{"v":1.22E-5,"d":"1.22E-05"},{"v":4.83e-05,"d":"4.83E-05"},0.219,"+/-","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["PDGFRB","GSK2256098",-0.236,0.256,0.859,{"v":2.07e-05,"d":"2.07E-05"},4.37,{"v":1.25e-05,"d":"1.25E-05"},{"v":4.86e-05,"d":"4.86E-05"},0.219,"0/+","FAK inhibitor","PTK2","Kinase inhibitor"]
["NOLC1","Pemetrexed",0.588,1.98E-3,-0.692,2.96E-3,-4.37,{"v":1.26E-5,"d":"1.26E-05"},{"v":4.91e-05,"d":"4.91E-05"},0.219,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["PDIA3","Sirolimus",-0.389,0.0545,0.806,1.63E-4,4.36,{"v":1.28e-05,"d":"1.28E-05"},{"v":4.91e-05,"d":"4.91E-05"},0.219,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["NPRL2","Prexasertib",-0.547,0.0047,0.722,1.57E-3,4.36,{"v":1.29E-5,"d":"1.29E-05"},{"v":4.93e-05,"d":"4.93E-05"},0.219,"-/+","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["PFDN2","BX_912",0.456,0.0219,-0.775,0.00042,-4.36,{"v":1.29E-5,"d":"1.29E-05"},{"v":4.96e-05,"d":"4.96E-05"},0.219,"+/-","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["PFDN4","RGFP966",0.526,0.00688,-0.735,0.00118,-4.36,{"v":1.32e-05,"d":"1.32E-05"},{"v":5.06e-05,"d":"5.06E-05"},0.219,"+/-","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["PFDN2","AT9283",0.331,0.106,-0.827,{"v":7.64E-5,"d":"7.64E-05"},-4.36,{"v":1.33E-5,"d":"1.33E-05"},{"v":5.06e-05,"d":"5.06E-05"},0.219,"0/-","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["ORAI1","Pemetrexed",-0.592,1.82E-3,0.687,3.29E-3,4.35,{"v":1.35e-05,"d":"1.35E-05"},{"v":5.13E-5,"d":"5.13E-05"},0.219,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["OPTN","Danusertib",-0.688,0.000143,0.59,0.0162,4.35,{"v":1.36E-5,"d":"1.36E-05"},{"v":5.16e-05,"d":"5.16E-05"},0.219,"-/+","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["MSN","Gemcitabine",-0.507,0.00971,0.746,0.000913,4.35,{"v":1.36E-5,"d":"1.36E-05"},{"v":5.16e-05,"d":"5.16E-05"},0.219,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["NSRP1","Tipifarnib",0.348,0.0886,-0.819,1.03E-4,-4.34,{"v":1.44e-05,"d":"1.44E-05"},{"v":5.41E-5,"d":"5.41E-05"},0.219,"0/-","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["MYBL2","Prexasertib",0.733,{"v":3.09e-05,"d":"3.09E-05"},-0.524,0.0371,-4.34,{"v":1.45E-5,"d":"1.45E-05"},{"v":5.41E-5,"d":"5.41E-05"},0.219,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["MTRR","ABT_751",0.692,0.000129,-0.581,0.0181,-4.33,{"v":1.47E-5,"d":"1.47E-05"},{"v":5.46e-05,"d":"5.46E-05"},0.219,"+/-","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["PLCL2","Glesatinib",-0.534,5.94E-3,0.725,1.47E-3,4.33,{"v":1.49E-5,"d":"1.49E-05"},{"v":5.46e-05,"d":"5.46E-05"},0.219,"-/+","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["NUP93","Vinblastine",0.464,0.0196,-0.767,0.000532,-4.33,{"v":1.51e-05,"d":"1.51E-05"},{"v":5.51e-05,"d":"5.51E-05"},0.219,"+/-","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["PIP4K2B","Gemcitabine",-0.575,2.63E-3,0.695,0.00278,4.33,{"v":1.51e-05,"d":"1.51E-05"},{"v":5.53e-05,"d":"5.53E-05"},0.219,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["OFD1","GSK_1070916",-0.361,0.0758,0.812,0.000132,4.32,{"v":1.54e-05,"d":"1.54E-05"},{"v":5.58e-05,"d":"5.58E-05"},0.219,"0/+","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["NAP1L5","Romidepsin",0.494,0.012,-0.749,0.000844,-4.32,{"v":1.55e-05,"d":"1.55E-05"},{"v":5.61e-05,"d":"5.61E-05"},0.219,"+/-","HDAC inhibitor","HDAC1;HDAC2","Differentiating.epigenetic modifier"]
["PBX1","AMG319",0.297,0.149,-0.835,{"v":5.75e-05,"d":"5.75E-05"},-4.32,{"v":1.58e-05,"d":"1.58E-05"},{"v":5.78e-05,"d":"5.78E-05"},0.219,"0/-","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["PLPP1","Etoposide",-0.606,1.32E-3,0.668,0.0047,4.32,{"v":1.59E-5,"d":"1.59E-05"},{"v":5.81e-05,"d":"5.81E-05"},0.219,"-/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["OPTN","TAK_901",-0.676,0.000211,0.597,0.0147,4.31,{"v":1.61e-05,"d":"1.61E-05"},{"v":5.81e-05,"d":"5.81E-05"},0.219,"-/+","Aurora, Src family, JAK3, RTK inhibitor","AURKA;AURKB;JAK3;SRC;CLK2;FGR;LRRK2;YES1;LCK;FYN;ABL1;AXL;ABL2;HCK;RET;FRK;NTRK1;FGFR2","Kinase inhibitor"]
["PISD","AT_406",0.305,0.138,-0.832,{"v":6.5e-05,"d":"6.50E-05"},-4.31,{"v":1.62e-05,"d":"1.62E-05"},{"v":5.81e-05,"d":"5.81E-05"},0.219,"0/-","XIAP, cIAP1, cIAP2 inhibitor","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["PACC1","AZD1152_HQPA",0.288,0.162,-0.836,{"v":5.39e-05,"d":"5.39E-05"},-4.3,{"v":1.67e-05,"d":"1.67E-05"},{"v":5.96e-05,"d":"5.96E-05"},0.219,"0/-","Aurora B inhibitor","AURKB","Kinase inhibitor"]
["PDXK","8_amino_adenosine",-0.399,0.0481,0.794,0.00024,4.3,{"v":1.69e-05,"d":"1.69E-05"},{"v":5.96e-05,"d":"5.96E-05"},0.219,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["NMRAL1","Losmapimod",0.115,0.585,-0.883,{"v":6e-06,"d":"6.00E-06"},-4.3,{"v":1.74e-05,"d":"1.74E-05"},{"v":6.08e-05,"d":"6.08E-05"},0.219,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["PFDN2","Axitinib",0.601,1.48E-3,-0.668,0.00469,-4.29,{"v":1.76e-05,"d":"1.76E-05"},{"v":6.08e-05,"d":"6.08E-05"},0.219,"+/-","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["PLK1","Cytarabine",0.688,0.000143,-0.576,0.0195,-4.29,{"v":1.78e-05,"d":"1.78E-05"},{"v":6.11e-05,"d":"6.11E-05"},0.219,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["RAD54B","Regorafenib",0.193,0.356,-0.885,{"v":5.31E-6,"d":"5.31E-06"},-4.55,{"v":5.32e-06,"d":"5.32E-06"},{"v":2.37E-5,"d":"2.37E-05"},0.219,"0/-","BRAF, c-Kit, VEGFR2 inhibitor","BRAF;RAF1;KIT;KDR;FLT1;RET;PDGFRB;FLT4","Kinase inhibitor"]
["RAB5C","GSK_461364",-0.662,0.000311,0.658,0.00561,4.53,{"v":5.82e-06,"d":"5.82E-06"},{"v":2.67e-05,"d":"2.67E-05"},0.219,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["RAB22A","Cytarabine",-0.623,0.000887,0.688,0.0032,4.5,{"v":6.8e-06,"d":"6.80E-06"},{"v":3.02e-05,"d":"3.02E-05"},0.219,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["PRKCD","Quizartinib",0.663,0.000304,-0.65,0.00639,-4.5,{"v":6.83e-06,"d":"6.83E-06"},{"v":3.04E-5,"d":"3.04E-05"},0.219,"+/-","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["SEC11A","Erastin",-0.809,{"v":9.63e-07,"d":"9.63E-07"},0.42,0.106,4.49,{"v":6.97e-06,"d":"6.97E-06"},{"v":3.07e-05,"d":"3.07E-05"},0.219,"-/0","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["RFX3","Gedatolisib",0.57,0.00291,-0.727,0.00143,-4.49,{"v":7.21e-06,"d":"7.21E-06"},{"v":3.09e-05,"d":"3.09E-05"},0.219,"+/-","PI3K, mTOR inhibitor","PIK3CA;PIK3CG;MTOR","Kinase inhibitor"]
["REX1BD","Imiquimod",-0.183,0.383,0.882,{"v":6.2e-06,"d":"6.20E-06"},4.49,{"v":7.24e-06,"d":"7.24E-06"},{"v":3.09e-05,"d":"3.09E-05"},0.219,"0/+","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["PRKCB","Cytarabine",-0.591,0.00185,0.71,0.00207,4.48,{"v":7.54e-06,"d":"7.54E-06"},{"v":3.21e-05,"d":"3.21E-05"},0.219,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["SCPEP1","Merestinib",0.458,0.0213,-0.79,0.000273,-4.48,{"v":7.6e-06,"d":"7.60E-06"},{"v":3.21e-05,"d":"3.21E-05"},0.219,"+/-","MET inhibitor","MET","Kinase inhibitor"]
["SAAL1","RGFP966",0.643,0.000526,-0.664,0.00499,-4.47,{"v":7.78e-06,"d":"7.78E-06"},{"v":3.26E-5,"d":"3.26E-05"},0.219,"+/-","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["PSMD7","Mercaptopurine",0.453,0.0228,-0.789,0.000278,-4.45,{"v":8.39e-06,"d":"8.39E-06"},{"v":3.31e-05,"d":"3.31E-05"},0.219,"+/-","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["PTPMT1","AR_42",-0.566,0.00317,0.724,0.00151,4.45,{"v":8.41e-06,"d":"8.41E-06"},{"v":3.31e-05,"d":"3.31E-05"},0.219,"-/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["RAD54B","Tivozanib",0.248,0.231,-0.863,{"v":1.69e-05,"d":"1.69E-05"},-4.45,{"v":8.44e-06,"d":"8.44E-06"},{"v":3.34e-05,"d":"3.34E-05"},0.219,"0/-","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["RELL1","Gemcitabine",-0.432,0.0309,0.797,0.000216,4.44,{"v":8.93e-06,"d":"8.93E-06"},{"v":3.46e-05,"d":"3.46E-05"},0.219,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["RAD51","Prexasertib",0.835,{"v":2.14e-07,"d":"2.14E-07"},-0.337,0.202,-4.44,{"v":8.96e-06,"d":"8.96E-06"},{"v":3.49e-05,"d":"3.49E-05"},0.219,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["PRMT2","PIM_447",-0.224,0.282,0.868,{"v":1.3e-05,"d":"1.30E-05"},4.44,{"v":9.02E-6,"d":"9.02E-06"},{"v":3.49e-05,"d":"3.49E-05"},0.219,"0/+","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["RAB22A","SN_38",-0.542,0.0051,0.737,0.00111,4.44,{"v":9.1e-06,"d":"9.10E-06"},{"v":3.49e-05,"d":"3.49E-05"},0.219,"-/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["PWP1","AT9283",0.298,0.148,-0.846,{"v":3.69e-05,"d":"3.69E-05"},-4.43,{"v":9.61e-06,"d":"9.61E-06"},{"v":3.71e-05,"d":"3.71E-05"},0.219,"0/-","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["RELL1","Pemetrexed",-0.556,0.00387,0.725,1.47E-3,4.42,{"v":9.84e-06,"d":"9.84E-06"},{"v":3.74e-05,"d":"3.74E-05"},0.219,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["PYCR2","Cladribine",0.72,{"v":4.91e-05,"d":"4.91E-05"},-0.562,0.0234,-4.41,{"v":1.01E-5,"d":"1.01E-05"},{"v":3.74e-05,"d":"3.74E-05"},0.219,"+/-","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["PSMG1","Pemetrexed",0.422,0.0354,-0.798,2.13E-4,-4.41,{"v":1.03E-5,"d":"1.03E-05"},{"v":3.84e-05,"d":"3.84E-05"},0.219,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["RESF1","Clofarabine",0.658,3.5E-4,-0.637,0.00799,-4.41,{"v":1.04E-5,"d":"1.04E-05"},{"v":3.89e-05,"d":"3.89E-05"},0.219,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["REX1BD","Perifosine",-0.107,0.61,0.891,{"v":3.57e-06,"d":"3.57E-06"},4.39,{"v":1.13E-5,"d":"1.13E-05"},{"v":4.16e-05,"d":"4.16E-05"},0.219,"0/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["RNF213","Cytarabine",-0.438,0.0286,0.788,0.000287,4.39,{"v":1.13E-5,"d":"1.13E-05"},{"v":4.16e-05,"d":"4.16E-05"},0.219,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["S100A16","Selinexor",-0.363,0.0743,0.819,1.03E-4,4.39,{"v":1.13E-5,"d":"1.13E-05"},{"v":4.16e-05,"d":"4.16E-05"},0.219,"0/+","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["SAP30L","Losmapimod",-0.26,0.209,0.853,{"v":2.62E-5,"d":"2.62E-05"},4.39,{"v":1.15E-5,"d":"1.15E-05"},{"v":4.16e-05,"d":"4.16E-05"},0.219,"0/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["SCPEP1","Foretinib",0.465,0.0192,-0.774,0.000436,-4.38,{"v":1.17E-5,"d":"1.17E-05"},{"v":4.19e-05,"d":"4.19E-05"},0.219,"+/-","MET, VEGFR2 inhibitor","MET;KDR","Kinase inhibitor"]
["RALGAPB","Clofarabine",-0.655,3.79E-4,0.634,0.00836,4.38,{"v":1.19E-5,"d":"1.19E-05"},{"v":4.21E-5,"d":"4.21E-05"},0.219,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["RELL1","Topotecan",-0.365,0.0727,0.817,1.1E-4,4.38,{"v":1.2E-5,"d":"1.20E-05"},{"v":4.24e-05,"d":"4.24E-05"},0.219,"0/+","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["SCAMP2","8_amino_adenosine",-0.746,{"v":1.88E-5,"d":"1.88E-05"},0.513,0.042,4.38,{"v":1.21e-05,"d":"1.21E-05"},{"v":4.29e-05,"d":"4.29E-05"},0.219,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["RAF1","Imiquimod",0.349,0.0872,-0.822,{"v":9.23e-05,"d":"9.23E-05"},-4.37,{"v":1.25e-05,"d":"1.25E-05"},{"v":4.39e-05,"d":"4.39E-05"},0.219,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["RELL1","Raltitrexed",-0.556,0.00388,0.717,0.00178,4.37,{"v":1.25e-05,"d":"1.25E-05"},{"v":4.39e-05,"d":"4.39E-05"},0.219,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["SH2D3C","Tozasertib",-0.568,0.00305,0.656,0.00575,4.09,{"v":4.29e-05,"d":"4.29E-05"},1.1E-4,0.219,"-/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["SLC29A1","Pemetrexed",0.718,{"v":5.28e-05,"d":"5.28E-05"},-0.483,0.0581,-4.09,{"v":4.32E-5,"d":"4.32E-05"},1.11E-4,0.219,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["SYNE2","LY_2874455",-0.49,0.0129,0.713,1.92E-3,4.09,{"v":4.35E-5,"d":"4.35E-05"},1.11E-4,0.219,"-/+","FGFR inhibitor","FGFR1;FGFR2;FGFR3","Kinase inhibitor"]
["SYVN1","IOX_2",0.412,0.0409,-0.758,0.000665,-4.09,{"v":4.38e-05,"d":"4.38E-05"},1.11E-4,0.219,"+/-","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["SPAG5","SN_38",0.532,0.00618,-0.684,3.49E-3,-4.09,{"v":4.39e-05,"d":"4.39E-05"},1.11E-4,0.219,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["SOWAHD","CC_223",-0.353,0.0834,0.786,3.1E-4,4.08,{"v":4.42e-05,"d":"4.42E-05"},1.12E-4,0.219,"0/+","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["SMYD3","Cytarabine",0.543,0.00507,-0.675,4.13E-3,-4.08,{"v":4.5e-05,"d":"4.50E-05"},1.15E-4,0.219,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["SRPK1","Hydroxyurea",0.384,0.0579,-0.771,4.75E-4,-4.08,{"v":4.51e-05,"d":"4.51E-05"},1.15E-4,0.219,"0/-","Antineoplastic agent","RRM1","Conv.Chemo"]
["TESC","Prexasertib",-0.325,0.112,0.796,2.22E-4,4.08,{"v":4.54e-05,"d":"4.54E-05"},1.15E-4,0.219,"0/+","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["TIGD2","Tasquinimod",0.11,0.601,-0.866,{"v":1.47E-5,"d":"1.47E-05"},-4.08,{"v":4.58e-05,"d":"4.58E-05"},1.16E-4,0.219,"0/-","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["TMEM9","Milciclib",0.569,2.98E-3,-0.652,0.00619,-4.07,{"v":4.61e-05,"d":"4.61E-05"},1.16E-4,0.219,"+/-","CDK2 inhibitor","CDK2;CDK4;CDK5;CDK7;NTRK1","Kinase inhibitor"]
["SPINT2","Tipifarnib",-0.497,0.0115,0.706,0.00222,4.07,{"v":4.63e-05,"d":"4.63E-05"},1.17E-4,0.219,"-/+","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["TIGD2","Imatinib",0.125,0.552,-0.861,{"v":1.8E-5,"d":"1.80E-05"},-4.07,{"v":4.66e-05,"d":"4.66E-05"},1.17E-4,0.219,"0/-","ABL, Kit, PDGFRB inhibitor","ABL1","Kinase inhibitor"]
["TMEM131L","Amsacrine",0.684,1.64E-4,-0.528,0.0354,-4.07,{"v":4.68e-05,"d":"4.68E-05"},1.18E-4,0.219,"+/-","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["SRSF3","Quizartinib",-0.468,0.0184,0.724,0.00152,4.07,{"v":4.75e-05,"d":"4.75E-05"},0.000119,0.219,"-/+","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["STK4","Cytarabine",-0.467,0.0185,0.724,0.00153,4.07,{"v":4.8e-05,"d":"4.80E-05"},1.2E-4,0.219,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["SPRTN","Cytarabine.Idarubicin",0.668,0.00026,-0.547,0.0285,-4.06,{"v":4.85E-5,"d":"4.85E-05"},1.21E-4,0.219,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["TMC8","Tozasertib",-0.365,0.0725,0.777,3.97E-4,4.06,{"v":4.86e-05,"d":"4.86E-05"},1.21E-4,0.219,"0/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["SIPA1","Temsirolimus",-0.172,0.411,0.847,{"v":3.42e-05,"d":"3.42E-05"},4.06,{"v":4.89e-05,"d":"4.89E-05"},1.21E-4,0.219,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SOS1","Nintedanib",-0.275,0.183,0.814,1.26E-4,4.06,{"v":4.92e-05,"d":"4.92E-05"},1.22E-4,0.219,"0/+","VEGFR, PDGFR, FGFR inhibitor","FGFR1;FGFR2;FLT1;FLT4;KDR;PDGFRA;PDGFRB","Kinase inhibitor"]
["TNKS","Etoposide",0.691,0.000133,-0.516,0.0407,-4.06,{"v":4.92e-05,"d":"4.92E-05"},1.22E-4,0.219,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["TMEM268","Bosutinib",0.341,0.0956,-0.787,0.000297,-4.05,{"v":5.02E-5,"d":"5.02E-05"},0.000124,0.219,"0/-","ABL, Src inhibitor","ABL1;LYN;HCK;SRC;EPHB2;NTRK1;NTRK2;TXK","Kinase inhibitor"]
["SIPA1","Sirolimus",-0.1,0.633,0.866,{"v":1.43E-5,"d":"1.43E-05"},4.05,{"v":5.02E-5,"d":"5.02E-05"},0.000124,0.219,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["TNFRSF1B","CC_223",-0.523,0.00734,0.684,0.00344,4.05,{"v":5.07e-05,"d":"5.07E-05"},1.25E-4,0.219,"-/+","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["TMC8","8_amino_adenosine",-0.53,6.45E-3,0.679,0.00384,4.05,{"v":5.13E-5,"d":"5.13E-05"},1.26E-4,0.219,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["TEDC2","RGFP966",0.561,0.00351,-0.653,0.00605,-4.05,{"v":5.17e-05,"d":"5.17E-05"},1.27E-4,0.219,"+/-","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["SLC27A1","BMS863233",-0.47,0.0178,0.719,0.00169,4.05,{"v":5.18e-05,"d":"5.18E-05"},1.27E-4,0.219,"-/+","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["SYK","Lonafarnib",-0.242,0.244,0.824,{"v":8.75e-05,"d":"8.75E-05"},4.05,{"v":5.2e-05,"d":"5.20E-05"},1.27E-4,0.219,"0/+","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["STN1","UNC0638",-0.416,0.0386,0.75,0.000823,4.05,{"v":5.21e-05,"d":"5.21E-05"},1.27E-4,0.219,"-/+","G9a, GLP inhibitor","EHMT2","Differentiating.epigenetic modifier"]
["TMEM120B","Pomalidomide",0.441,0.0274,-0.735,0.00118,-4.04,{"v":5.35e-05,"d":"5.35E-05"},0.000131,0.219,"+/-","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["TET3","Mercaptopurine",-0.261,0.207,0.816,1.15E-4,4.04,{"v":5.36e-05,"d":"5.36E-05"},0.000131,0.219,"0/+","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["TOM1L2","Dactolisib",-0.584,0.00218,0.632,0.00863,4.04,{"v":5.37e-05,"d":"5.37E-05"},0.000131,0.219,"-/+","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;ATR;RPS6KB1","Kinase inhibitor"]
["SMARCA5","Vidofludimus",0.617,0.00102,-0.6,0.0141,-4.04,{"v":5.37e-05,"d":"5.37E-05"},0.000131,0.219,"+/-","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["TBP","Palomid_529",-0.61,0.00122,0.607,0.0127,4.04,{"v":5.45e-05,"d":"5.45E-05"},0.000133,0.219,"-/+","AKT, MTOR, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3;MTOR","Kinase inhibitor"]
["SMG1","Prexasertib",0.563,0.00336,-0.649,0.00653,-4.03,{"v":5.48e-05,"d":"5.48E-05"},0.000133,0.219,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["SRPK1","Prexasertib",0.72,{"v":4.91e-05,"d":"4.91E-05"},-0.464,0.0699,-4.03,{"v":5.48e-05,"d":"5.48E-05"},0.000133,0.219,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["SYVN1","Exemestane",0.414,0.0396,-0.749,0.000842,-4.03,{"v":5.5e-05,"d":"5.50E-05"},1.34E-4,0.219,"+/-","Aromatase inhibitor","CYP19A1","Hormone therapy"]
["SPN","Ridaforolimus",-0.406,0.0438,0.753,0.000768,4.03,{"v":5.55e-05,"d":"5.55E-05"},1.34E-4,0.219,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["TMC6","Tozasertib",-0.472,0.0171,0.715,0.00186,4.03,{"v":5.58e-05,"d":"5.58E-05"},1.35E-4,0.219,"-/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["SLC25A29","Perifosine",-0.0397,0.851,-0.896,{"v":2.75e-06,"d":"2.75E-06"},-4.03,{"v":5.59e-05,"d":"5.59E-05"},1.35E-4,0.219,"0/-","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["SFT2D3","Carboplatin",0.6,0.00152,-0.614,0.0113,-4.03,{"v":5.6e-05,"d":"5.60E-05"},1.35E-4,0.219,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["SH3BP2","AT9283",-0.605,0.00135,0.609,0.0122,4.03,{"v":5.6e-05,"d":"5.60E-05"},1.35E-4,0.219,"-/+","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["SETD2","SB743921",0.419,0.0373,-0.746,0.000914,-4.03,{"v":5.63E-5,"d":"5.63E-05"},1.37E-4,0.219,"+/-","Mitotic inhibitor, Eg5, KSP inhibitor","KIF11","Kinesin inhibitor"]
["SLC25A40","Flutamide",0.111,0.597,-0.861,{"v":1.84E-5,"d":"1.84E-05"},-4.03,{"v":5.65e-05,"d":"5.65E-05"},1.37E-4,0.219,"0/-","Nonsteroidal antiandrogen","AR;AHR;NR1I2","Hormone therapy"]
["STX7","Palbociclib",-0.59,1.89E-3,0.623,0.00989,4.03,{"v":5.65e-05,"d":"5.65E-05"},1.37E-4,0.219,"-/+","Topoisomerase I inhibitor, Camptothecin analog","CDK4;CDK6","Kinase inhibitor"]
["CDC45","Pemetrexed",0.609,1.23E-3,-0.709,0.00212,-4.55,{"v":5.38e-06,"d":"5.38E-06"},{"v":3.19e-05,"d":"3.19E-05"},0.22,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["CENPJ","Prexasertib",0.675,0.000215,-0.648,0.00668,-4.55,{"v":5.43e-06,"d":"5.43E-06"},{"v":3.24e-05,"d":"3.24E-05"},0.22,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["CLIC1","8_amino_adenosine",-0.282,0.172,0.861,{"v":1.86e-05,"d":"1.86E-05"},4.53,{"v":5.76e-06,"d":"5.76E-06"},{"v":3.41e-05,"d":"3.41E-05"},0.22,"0/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["EEF1AKNMT","AZD_8186",0.354,0.0829,-0.839,{"v":4.91e-05,"d":"4.91E-05"},-4.53,{"v":5.76e-06,"d":"5.76E-06"},{"v":3.41e-05,"d":"3.41E-05"},0.22,"0/-","PI3K beta inhibitor","PIK3CG","Kinase inhibitor"]
["CPOX","Gilteritinib",-0.164,0.433,0.889,{"v":4.03e-06,"d":"4.03E-06"},4.53,{"v":5.89e-06,"d":"5.89E-06"},{"v":3.44e-05,"d":"3.44E-05"},0.22,"0/+","FLT3, AXL inhibitor","FLT3","Kinase inhibitor"]
["CKAP2","Prexasertib",0.729,{"v":3.55e-05,"d":"3.55E-05"},-0.574,0.0202,-4.52,{"v":6.31e-06,"d":"6.31E-06"},{"v":3.61e-05,"d":"3.61E-05"},0.22,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["CTU2","A_1331852",-0.603,1.42E-3,0.707,0.00218,4.52,{"v":6.33e-06,"d":"6.33E-06"},{"v":3.61e-05,"d":"3.61E-05"},0.22,"-/+","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2;MCL1","Apoptotic modulator"]
["CHORDC1","Midostaurin",0.659,0.000344,-0.657,0.00565,-4.51,{"v":6.39e-06,"d":"6.39E-06"},{"v":3.64e-05,"d":"3.64E-05"},0.22,"+/-","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["CYBB","I_BET151",-0.656,0.000369,0.659,0.00551,4.51,{"v":6.57e-06,"d":"6.57E-06"},{"v":3.74e-05,"d":"3.74E-05"},0.22,"-/+","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["DNAJA1","Pemetrexed",0.803,{"v":1.37E-6,"d":"1.37E-06"},-0.438,0.0895,-4.51,{"v":6.58e-06,"d":"6.58E-06"},{"v":3.74e-05,"d":"3.74E-05"},0.22,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["DNA2","Pemetrexed",0.636,0.000634,-0.677,0.004,-4.5,{"v":6.81E-6,"d":"6.81E-06"},{"v":3.84e-05,"d":"3.84E-05"},0.22,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["DNA2","Cytarabine.Idarubicin",0.593,0.00178,-0.712,1.98E-3,-4.5,{"v":6.89e-06,"d":"6.89E-06"},{"v":3.91e-05,"d":"3.91E-05"},0.22,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["CHORDC1","BX_912",0.627,0.000791,-0.682,0.00358,-4.49,{"v":7.15e-06,"d":"7.15E-06"},{"v":4.09e-05,"d":"4.09E-05"},0.22,"+/-","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["CKAP5","Clofarabine",0.532,0.00622,-0.752,0.000778,-4.49,{"v":7.15e-06,"d":"7.15E-06"},{"v":4.09e-05,"d":"4.09E-05"},0.22,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["CD200","GSK_461364",-0.61,0.00119,0.697,0.00272,4.49,{"v":7.17E-6,"d":"7.17E-06"},{"v":4.09e-05,"d":"4.09E-05"},0.22,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["DDX5","Raltitrexed",0.646,0.000487,-0.665,0.00494,-4.49,{"v":7.19e-06,"d":"7.19E-06"},{"v":4.09e-05,"d":"4.09E-05"},0.22,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["CLEC2B","Merestinib",0.832,{"v":2.47e-07,"d":"2.47E-07"},-0.352,0.181,-4.47,{"v":7.83e-06,"d":"7.83E-06"},{"v":4.24e-05,"d":"4.24E-05"},0.22,"+/0","MET inhibitor","MET","Kinase inhibitor"]
["CIZ1","NVP_CGM097",0.506,0.00987,-0.763,0.000579,-4.46,{"v":8.04e-06,"d":"8.04E-06"},{"v":4.31e-05,"d":"4.31E-05"},0.22,"+/-","p53-MDM2 inhibitor","TP53;MDM2","Apoptotic modulator"]
["DCAF12","Hydroxyurea",0.785,{"v":3.33e-06,"d":"3.33E-06"},-0.461,0.0722,-4.45,{"v":8.48e-06,"d":"8.48E-06"},{"v":4.49E-5,"d":"4.49E-05"},0.22,"+/0","Antineoplastic agent","RRM1","Conv.Chemo"]
["DPYSL4","AZD7762",-0.442,0.0271,0.794,0.000239,4.45,{"v":8.59e-06,"d":"8.59E-06"},{"v":4.49E-5,"d":"4.49E-05"},0.22,"-/+","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["DDX5","Cytarabine.Idarubicin",0.717,{"v":5.53e-05,"d":"5.53E-05"},-0.575,0.0198,-4.45,{"v":8.64e-06,"d":"8.64E-06"},{"v":4.51e-05,"d":"4.51E-05"},0.22,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["CWC27","AT9283",0.591,0.00186,-0.704,0.00234,-4.44,{"v":8.86e-06,"d":"8.86E-06"},{"v":4.56e-05,"d":"4.56E-05"},0.22,"+/-","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["CKAP5","Cytarabine.Idarubicin",0.693,1.22E-4,-0.604,0.0133,-4.44,{"v":8.96e-06,"d":"8.96E-06"},{"v":4.59e-05,"d":"4.59E-05"},0.22,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["CSPP1","Cytarabine.Idarubicin",0.632,0.000707,-0.669,0.00461,-4.44,{"v":9.05e-06,"d":"9.05E-06"},{"v":4.61e-05,"d":"4.61E-05"},0.22,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["CD200","Tipifarnib",-0.565,0.00324,0.722,1.58E-3,4.44,{"v":9.07e-06,"d":"9.07E-06"},{"v":4.61e-05,"d":"4.61E-05"},0.22,"-/+","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["CHAF1B","Cytarabine",0.512,0.0089,-0.756,0.000711,-4.43,{"v":9.25e-06,"d":"9.25E-06"},{"v":4.66e-05,"d":"4.66E-05"},0.22,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["DDX19A","Cabazitaxel",0.432,0.0311,-0.796,2.24E-4,-4.43,{"v":9.32e-06,"d":"9.32E-06"},{"v":4.71E-5,"d":"4.71E-05"},0.22,"+/-","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["DPP7","Gemcitabine",-0.663,0.000304,0.637,0.00801,4.43,{"v":9.32e-06,"d":"9.32E-06"},{"v":4.71E-5,"d":"4.71E-05"},0.22,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["ERGIC1","Uprosertib",-0.351,0.0856,0.808,0.000153,4.25,{"v":2.12E-5,"d":"2.12E-05"},{"v":7.2e-05,"d":"7.20E-05"},0.22,"0/+","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["ERLEC1","AZD8055",-0.725,{"v":4.15e-05,"d":"4.15E-05"},0.515,0.0413,4.25,{"v":2.13e-05,"d":"2.13E-05"},{"v":7.2e-05,"d":"7.20E-05"},0.22,"-/+","mTOR inhibitor","MTOR","Kinase inhibitor"]
["ITIH3","Thioguanine",-0.439,0.0282,0.744,0.000955,4.09,{"v":4.37e-05,"d":"4.37E-05"},1.21E-4,0.22,"-/+","Antimetabolite, Purine analog","DNMT1","Conv.Chemo"]
["ITPR3","Nintedanib",-0.579,0.00241,0.646,0.00692,4.08,{"v":4.41e-05,"d":"4.41E-05"},1.21E-4,0.22,"-/+","VEGFR, PDGFR, FGFR inhibitor","FGFR1;FGFR2;FLT1;FLT4;KDR;PDGFRA;PDGFRB","Kinase inhibitor"]
["LRR1","Tubacin",0.273,0.187,-0.817,1.11E-4,-4.08,{"v":4.41e-05,"d":"4.41E-05"},1.22E-4,0.22,"0/-","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["BCLAF3","Erdafitinib",-0.359,0.0781,0.724,0.00153,3.69,2.24E-4,0.000366,0.221,"0/+","FGFR inhibitor","FGFR1;FGFR2;FGFR3;FGFR4","Kinase inhibitor"]
["ARHGAP23","Epirubicin",0.256,0.217,-0.774,0.000439,-3.69,0.000225,0.000367,0.221,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["AC093323.1","Docetaxel",0.416,0.0384,-0.69,0.00311,-3.69,0.000225,3.68E-4,0.221,"+/-","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["CC2D1B","SN_38",-0.341,0.0949,0.733,1.25E-3,3.69,0.000226,0.000369,0.221,"0/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["AMMECR1L","GSK650394",0.159,0.448,-0.811,0.000138,-3.69,0.000226,0.000369,0.221,"0/-","SGK1 and 2 inhibitor","SGK1","Kinase inhibitor"]
["ANKRD13A","SN_38",-0.368,0.0699,0.718,1.74E-3,3.69,0.000226,0.00037,0.221,"0/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["ACOT2","Abexinostat",-0.344,0.0921,0.731,0.00129,3.69,0.000227,0.000371,0.221,"0/+","HDAC1 selective inhibitor","HDAC1","Differentiating.epigenetic modifier"]
["BTG3","Tozasertib",0.535,0.00588,-0.6,0.014,-3.69,0.000227,0.000371,0.221,"+/-","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["CASC3","BMS863233",0.274,0.186,-0.765,0.000551,-3.69,0.000228,0.000371,0.221,"0/-","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["AASDHPPT","GSK_461364",0.589,0.00195,-0.546,0.0285,-3.69,0.000228,0.000372,0.221,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["AC207582.2","SN_38",-0.356,0.0807,0.724,1.5E-3,3.69,0.000228,0.000373,0.221,"0/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["ANXA11","Gemcitabine",-0.544,0.00495,0.591,0.0159,3.68,0.000229,0.000373,0.221,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["ARHGEF11","Tirabrutinib",0.395,0.0505,-0.702,0.00245,-3.68,0.00023,0.000373,0.221,"0/-","BTK inhibitor","BTK","Kinase inhibitor"]
["GNPDA2","Pemetrexed",-0.696,1.1E-4,0.555,0.0256,4.25,{"v":2.16E-5,"d":"2.16E-05"},{"v":7.33e-05,"d":"7.33E-05"},0.221,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["HIRIP3","Imiquimod",0.211,0.312,-0.854,{"v":2.52e-05,"d":"2.52E-05"},-4.25,{"v":2.16E-5,"d":"2.16E-05"},{"v":7.35e-05,"d":"7.35E-05"},0.221,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["FBLL1","BMS863233",0.0675,0.748,-0.889,{"v":4.1e-06,"d":"4.10E-06"},-4.25,{"v":2.18e-05,"d":"2.18E-05"},{"v":7.4e-05,"d":"7.40E-05"},0.221,"0/-","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["LLPH","VER_155008",0.611,0.00119,-0.616,0.0111,-4.08,{"v":4.47e-05,"d":"4.47E-05"},0.000124,0.221,"+/-","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["KIF18A","Cytarabine",0.769,{"v":6.93e-06,"d":"6.93E-06"},-0.387,0.138,-4.08,{"v":4.48e-05,"d":"4.48E-05"},0.000124,0.221,"+/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["L3HYPDH","Crenolanib",0.779,{"v":4.53e-06,"d":"4.53E-06"},-0.367,0.162,-4.08,{"v":4.52e-05,"d":"4.52E-05"},1.25E-4,0.221,"+/0","PDGFRA and PDGFRB inhibitor","PDGFRA","Kinase inhibitor"]
["MLLT11","NVP_BGT226",0.622,0.000909,-0.604,0.0133,-4.08,{"v":4.55e-05,"d":"4.55E-05"},1.26E-4,0.221,"+/-","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CG;MTOR","Kinase inhibitor"]
["KNSTRN","Trifluridine",0.804,{"v":1.3E-6,"d":"1.30E-06"},-0.307,0.247,-4.08,{"v":4.55e-05,"d":"4.55E-05"},1.26E-4,0.221,"+/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["MGMT","Asciminib",0.129,0.538,-0.861,{"v":1.87e-05,"d":"1.87E-05"},-4.08,{"v":4.56e-05,"d":"4.56E-05"},1.26E-4,0.221,"0/-","Allosteric ABL inhibitor, blocks myristoyl binding","ABL1","Kinase inhibitor"]
["MMS19","Erlotinib",-0.454,0.0227,0.734,0.00122,4.08,{"v":4.59e-05,"d":"4.59E-05"},1.27E-4,0.221,"-/+","EGFR inhibitor","EGFR","Kinase inhibitor"]
["KLHL25","Ribociclib",0.695,0.000114,-0.513,0.042,-4.07,{"v":4.61e-05,"d":"4.61E-05"},1.27E-4,0.221,"+/-","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["MANBA","8_amino_adenosine",-0.442,0.0269,0.74,1.06E-3,4.07,{"v":4.67e-05,"d":"4.67E-05"},0.000128,0.221,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["KIF11","SN_38",0.668,0.00026,-0.547,0.0283,-4.07,{"v":4.8e-05,"d":"4.80E-05"},0.00013,0.221,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["LXN","Ganetespib",-0.666,0.00028,0.549,0.0276,4.06,{"v":4.92e-05,"d":"4.92E-05"},0.000133,0.221,"-/+","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["KIF23","Prexasertib",0.634,0.000662,-0.586,0.0171,-4.06,{"v":4.93e-05,"d":"4.93E-05"},1.34E-4,0.221,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["KATNA1","Imiquimod",-0.321,0.117,0.795,0.00023,4.06,{"v":4.99E-5,"d":"4.99E-05"},1.35E-4,0.221,"0/+","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["KMO","Belinostat",0.622,0.000912,-0.598,0.0143,-4.05,{"v":5.03e-05,"d":"5.03E-05"},1.36E-4,0.221,"+/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["KIAA1143","Exemestane",0.525,0.007,-0.683,0.00356,-4.05,{"v":5.04e-05,"d":"5.04E-05"},1.36E-4,0.221,"+/-","Aromatase inhibitor","CYP19A1","Hormone therapy"]
["LAMTOR3","Prexasertib",-0.803,{"v":1.36e-06,"d":"1.36E-06"},0.301,0.257,4.05,{"v":5.09e-05,"d":"5.09E-05"},1.37E-4,0.221,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["LAMTOR2","Prexasertib",-0.822,{"v":4.62e-07,"d":"4.62E-07"},0.248,0.354,4.05,{"v":5.09e-05,"d":"5.09E-05"},1.37E-4,0.221,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["METTL7A","Lonafarnib",-0.496,0.0117,0.703,0.00239,4.05,{"v":5.1E-5,"d":"5.10E-05"},1.37E-4,0.221,"-/+","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["JPT2","Losmapimod",0.396,0.0499,-0.761,0.000624,-4.05,{"v":5.12e-05,"d":"5.12E-05"},0.000138,0.221,"+/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["ITGAL","Masitinib",-0.0636,0.763,0.875,{"v":9.32e-06,"d":"9.32E-06"},4.05,{"v":5.16e-05,"d":"5.16E-05"},0.000138,0.221,"0/+","KIT inhibitor","KIT","Kinase inhibitor"]
["KIDINS220","Cytarabine.Idarubicin",0.632,0.000707,-0.586,0.0171,-4.05,{"v":5.18e-05,"d":"5.18E-05"},0.000138,0.221,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["MAP3K8","NVP_LCL161",-0.0336,0.873,0.881,{"v":6.52e-06,"d":"6.52E-06"},4.04,{"v":5.27E-5,"d":"5.27E-05"},0.000139,0.221,"0/+","IAPs, SMAC mimetic","XIAP;BIRC2","Apoptotic modulator"]
["IDH3A","Foretinib",0.549,0.00446,-0.662,0.00518,-4.04,{"v":5.28e-05,"d":"5.28E-05"},0.00014,0.221,"+/-","MET, VEGFR2 inhibitor","MET;KDR","Kinase inhibitor"]
["KPNA2","Cytarabine.Idarubicin",0.687,0.000148,-0.517,0.0405,-4.04,{"v":5.28e-05,"d":"5.28E-05"},0.00014,0.221,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["IL2RG","Simvastatin",-0.135,0.519,0.856,{"v":2.33e-05,"d":"2.33E-05"},4.04,{"v":5.29e-05,"d":"5.29E-05"},0.00014,0.221,"0/+","HMG CoA reductase inhibitor","HMGCR","Metabolic modifier"]
["MAT2A","Raltitrexed",0.752,{"v":1.49E-5,"d":"1.49E-05"},-0.412,0.113,-4.04,{"v":5.3e-05,"d":"5.30E-05"},0.00014,0.221,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["MICU1","Ridaforolimus",-0.431,0.0316,0.741,0.00102,4.04,{"v":5.31e-05,"d":"5.31E-05"},0.00014,0.221,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["KIF2C","Prexasertib",0.773,{"v":6.03e-06,"d":"6.03E-06"},-0.368,0.16,-4.04,{"v":5.36e-05,"d":"5.36E-05"},0.00014,0.221,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["MBOAT7","Cytarabine.Idarubicin",-0.718,{"v":5.3e-05,"d":"5.30E-05"},0.47,0.0665,4.04,{"v":5.36e-05,"d":"5.36E-05"},0.00014,0.221,"-/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["ZNHIT3","Trifluridine",0.673,0.00023,-0.568,0.0217,-4.17,{"v":2.99e-05,"d":"2.99E-05"},{"v":7.61e-05,"d":"7.61E-05"},0.221,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["BCL7C","Dovitinib",-0.558,0.00373,0.577,0.0193,3.68,0.00023,0.000376,0.222,"-/+","FGFR inhibitor","FGFR1;FGFR3;KIT;FLT3;FLT4","Kinase inhibitor"]
["KLF12","GSK269962",0.393,0.0521,-0.76,0.000628,-4.04,{"v":5.42e-05,"d":"5.42E-05"},0.000141,0.222,"0/-","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["KCMF1","AT9283",0.233,0.263,-0.825,{"v":8.27e-05,"d":"8.27E-05"},-4.03,{"v":5.55e-05,"d":"5.55E-05"},1.44E-4,0.222,"0/-","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["IGSF8","Fostamatinib",0.222,0.287,-0.829,{"v":7.22e-05,"d":"7.22E-05"},-4.03,{"v":5.56e-05,"d":"5.56E-05"},1.45E-4,0.222,"0/-","SYK inhibitor","SYK","Kinase inhibitor"]
["IDS","Cytarabine",-0.533,0.00608,0.672,0.00433,4.03,{"v":5.62e-05,"d":"5.62E-05"},1.45E-4,0.222,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["LRCH4","8_amino_adenosine",-0.509,0.00931,0.69,0.00312,4.03,{"v":5.64e-05,"d":"5.64E-05"},1.46E-4,0.222,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["KIFC1","Verdinexor",0.503,0.0104,-0.694,0.00287,-4.03,{"v":5.68e-05,"d":"5.68E-05"},1.46E-4,0.222,"+/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["KIF18A","Prexasertib",0.8,{"v":1.56e-06,"d":"1.56E-06"},-0.299,0.261,-4.02,{"v":5.72e-05,"d":"5.72E-05"},1.47E-4,0.222,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["M6PR","Everolimus",-0.319,0.12,0.792,0.000255,4.02,{"v":5.76e-05,"d":"5.76E-05"},1.47E-4,0.222,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["MCFD2","Sabutoclax",0.0821,0.696,-0.868,{"v":1.32e-05,"d":"1.32E-05"},-4.02,{"v":5.78e-05,"d":"5.78E-05"},0.000148,0.222,"0/-","pan Bcl-2 family inhibitor","BCL2;BCL2L1;MCL1;BCL2A1","Apoptotic modulator"]
["LGALS3BP","Cladribine",-0.436,0.0293,0.735,0.00118,4.02,{"v":5.78e-05,"d":"5.78E-05"},0.000148,0.222,"-/+","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["APH1A","8_amino_adenosine",-0.526,0.00687,0.606,0.0128,3.68,2.31E-4,3.79E-4,0.223,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["BCOR","AZD1208",0.339,0.0973,-0.733,1.24E-3,-3.68,2.32E-4,3.79E-4,0.223,"0/-","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["C12orf45","Tozasertib",0.345,0.0911,-0.73,1.34E-3,-3.68,2.33E-4,0.00038,0.223,"0/-","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["AFF3","Cytarabine",-0.188,0.367,0.799,2.03E-4,3.68,2.34E-4,0.000381,0.223,"0/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ATM","VER_155008",-0.591,0.00185,0.542,0.03,3.68,2.34E-4,0.000381,0.223,"-/+","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["BRPF1","Eribulin",-0.352,0.084,0.725,1.48E-3,3.68,0.000235,0.000382,0.223,"0/+","Mitotic inhibitor, microtubule depolymerizer","TUBB1","Conv.Chemo"]
["C1orf112","AZD_1080",0.608,1.25E-3,-0.523,0.0378,-3.68,0.000236,0.000384,0.223,"+/-","GSK3 inhibitor","GSK3B;GSK3A","Kinase inhibitor"]
["ARID4A","Tivozanib",-0.62,9.5E-4,0.509,0.044,3.68,0.000236,3.86E-4,0.223,"-/+","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["ATG9A","Temsirolimus",-0.395,0.0505,0.7,0.00252,3.68,0.000237,3.86E-4,0.223,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ATP13A1","Cabazitaxel",-0.363,0.0741,0.719,0.00171,3.68,0.000237,0.000387,0.223,"0/+","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["ABRACL","Gemcitabine",-0.493,0.0123,0.632,8.6E-3,3.67,0.000239,0.000387,0.223,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["BABAM2","Glesatinib",0.48,0.0151,-0.642,0.00733,-3.67,0.000239,3.88E-4,0.223,"+/-","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["ARHGEF40","Erdafitinib",-0.418,0.0377,0.686,0.00335,3.67,0.000239,0.00039,0.223,"-/+","FGFR inhibitor","FGFR1;FGFR2;FGFR3;FGFR4","Kinase inhibitor"]
["CAB39","VER_155008",-0.427,0.0331,0.679,3.79E-3,3.67,0.00024,0.000391,0.223,"-/+","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["CBX4","Sitravatinib",-0.38,0.0607,0.708,0.00213,3.67,0.00024,0.000391,0.223,"0/+","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["C1QBP","Canertinib",0.144,0.491,-0.814,0.000124,-3.67,2.41E-4,0.000392,0.223,"0/-","Pan-HER inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["AP3S1","8_amino_adenosine",-0.466,0.0189,0.652,0.00616,3.67,2.41E-4,0.000393,0.223,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["ANXA4","Mitoxantrone",-0.617,1.01E-3,0.511,0.0432,3.67,2.41E-4,0.000393,0.223,"-/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["ATP5MD","MK_8745",-0.374,0.0654,0.712,1.98E-3,3.67,2.41E-4,0.000393,0.223,"0/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["AC207582.2","WEHI_539",0.713,{"v":6.42e-05,"d":"6.42E-05"},-0.373,0.155,-3.67,2.41E-4,0.000393,0.223,"+/0","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["CC2D1B","Cytarabine.Idarubicin",-0.423,0.0352,0.682,0.00361,3.67,2.42E-4,0.000393,0.223,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["ATP2B4","Raltitrexed",-0.543,0.00505,0.589,0.0164,3.67,2.43E-4,0.000394,0.223,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["AARS1","Fludarabine",0.515,0.00842,-0.613,0.0115,-3.67,2.43E-4,0.000394,0.223,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["C10orf88","Aldoxorubicin",0.545,0.00483,-0.586,0.017,-3.67,0.000244,0.000394,0.223,"+/-","Topoisomerase II inhibitor, Albumin binding","TOP2A;TOP2B","Conv.Chemo"]
["ATP6V1D","Vidofludimus",-0.471,0.0174,0.648,0.00666,3.67,0.000244,0.000395,0.223,"-/+","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["ARID4A","CCT196969",-0.622,0.000911,0.505,0.0463,3.67,0.000245,0.000396,0.223,"-/+","pan-RAF, Src inhibitor","RAF1;BRAF;SRC;LCK","Kinase inhibitor"]
["CAB39L","Sotrastaurin",-0.494,0.0122,0.63,0.00884,3.67,0.000245,0.000396,0.223,"-/+","PKC inhibitor","PRKCB;PRKCQ;PRKCH;PRKCA;PRKCE;PRKCA","Kinase inhibitor"]
["ASRGL1","Seliciclib",0.283,0.17,-0.758,0.000666,-3.67,0.000245,3.97E-4,0.223,"0/-","CDK2, 7, 9 inhibitor","CDK2;CDK1;CDK5;MAPK1;MAPK3","Kinase inhibitor"]
["ALKBH3","Valrubicin",-0.262,0.206,0.768,0.000517,3.67,0.000246,3.97E-4,0.223,"0/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["BUB1","8_amino_adenosine",0.572,2.81E-3,-0.559,0.0243,-3.67,0.000246,3.97E-4,0.223,"+/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["BTBD10","Rocilinostat",0.393,0.0517,-0.699,0.00257,-3.66,0.000248,0.000398,0.223,"0/-","HDAC6 selective inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["BRD9","Pevonedistat",0.361,0.0761,-0.718,1.74E-3,-3.66,0.000249,0.000398,0.223,"0/-","NAE inhibitor","NAE1","Metabolic modifier"]
["CCDC12","Exemestane",0.291,0.159,-0.754,0.000741,-3.66,0.000249,0.000399,0.223,"0/-","Aromatase inhibitor","CYP19A1","Hormone therapy"]
["AC005747.1","Finasteride",0.366,0.0724,-0.715,0.00184,-3.66,0.00025,0.000401,0.223,"0/-","type II 5-alpha reductase inhibitor","SRD5A2","Hormone therapy"]
["C10orf88","Cytarabine.Idarubicin",0.581,2.32E-3,-0.549,0.0277,-3.66,0.000251,0.000401,0.223,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["GMNN","WEHI_539",-0.598,0.00159,0.661,0.00533,4.24,{"v":2.21e-05,"d":"2.21E-05"},{"v":7.58e-05,"d":"7.58E-05"},0.223,"-/+","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["FADS3","ENMD_2076",-0.523,0.00733,0.717,0.00177,4.24,{"v":2.27E-5,"d":"2.27E-05"},{"v":7.68e-05,"d":"7.68E-05"},0.223,"-/+","pan-Aurora, VEGFR inhibitor","AURKA;FLT3;RET;FLT4;SRC;CSF1R;NTRK1;PDGFRA;BLK;KDR;YES1;FYN;AURKB;PTK2;FGFR2;FGFR1;JAK2;KIT;ABL1","Kinase inhibitor"]
["FRMD4A","Dovitinib",0.687,1.47E-4,-0.564,0.0228,-4.24,{"v":2.28e-05,"d":"2.28E-05"},{"v":7.68e-05,"d":"7.68E-05"},0.223,"+/-","FGFR inhibitor","FGFR1;FGFR3;KIT;FLT3;FLT4","Kinase inhibitor"]
["FAM221A","Masitinib",0.338,0.0989,-0.811,0.00014,-4.23,{"v":2.33e-05,"d":"2.33E-05"},{"v":7.75E-5,"d":"7.75E-05"},0.223,"0/-","KIT inhibitor","KIT","Kinase inhibitor"]
["FGD3","Mercaptopurine",-0.487,0.0136,0.738,1.09E-3,4.23,{"v":2.38e-05,"d":"2.38E-05"},{"v":7.87e-05,"d":"7.87E-05"},0.223,"-/+","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["FIP1L1","Selinexor",0.513,0.00874,-0.722,0.00159,-4.23,{"v":2.38e-05,"d":"2.38E-05"},{"v":7.87e-05,"d":"7.87E-05"},0.223,"+/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["LGALS9","Tubastatin_A",0.468,0.0184,-0.716,1.81E-3,-4.02,{"v":5.82e-05,"d":"5.82E-05"},0.000149,0.223,"+/-","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["KIAA0319L","Pexidartinib",0.751,{"v":1.52E-5,"d":"1.52E-05"},-0.405,0.119,-4.02,{"v":5.89e-05,"d":"5.89E-05"},0.00015,0.223,"+/0","KIT, CSF1R, FLT3 inhibitor","CSF1R;FLT3;KIT","Kinase inhibitor"]
["TAF9B","Pomalidomide",-0.318,0.121,0.792,0.000258,4.02,{"v":5.85e-05,"d":"5.85E-05"},0.000141,0.223,"0/+","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["SURF2","Tipifarnib",0.604,0.00138,-0.608,0.0125,-4.02,{"v":5.88e-05,"d":"5.88E-05"},0.000142,0.223,"+/-","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["TMEM189","Pomalidomide",0.412,0.0409,-0.748,0.000867,-4.02,{"v":5.89e-05,"d":"5.89E-05"},0.000142,0.223,"+/-","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["TMEM259","Pomalidomide",0.208,0.319,-0.832,{"v":6.44e-05,"d":"6.44E-05"},-4.02,{"v":5.9e-05,"d":"5.90E-05"},0.000142,0.223,"0/-","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["TXNDC12","Paclitaxel",0.409,0.0425,-0.771,4.66E-4,-4.17,{"v":3.08e-05,"d":"3.08E-05"},{"v":7.74e-05,"d":"7.74E-05"},0.223,"+/-","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["C18orf25","Dexamethasone",-0.168,0.423,0.805,0.000171,3.66,0.000251,0.000402,0.224,"0/+","Glucocorticoid, immunomodulatory agent","NR3C1","Immunomodulatory"]
["ATP5F1B","Paclitaxel",-0.216,0.3,0.786,0.000306,3.66,0.000253,0.000403,0.224,"0/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["BCDIN3D","Methotrexate",0.232,0.265,-0.779,0.000372,-3.66,0.000254,0.000404,0.224,"0/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["BLZF1","Gedatolisib",-0.243,0.243,0.775,0.000424,3.66,0.000254,0.000405,0.224,"0/+","PI3K, mTOR inhibitor","PIK3CA;PIK3CG;MTOR","Kinase inhibitor"]
["ABRAXAS1","Nintedanib",0.194,0.352,-0.794,0.000238,-3.66,0.000254,4.06E-4,0.224,"0/-","VEGFR, PDGFR, FGFR inhibitor","FGFR1;FGFR2;FLT1;FLT4;KDR;PDGFRA;PDGFRB","Kinase inhibitor"]
["C4orf3","Fludarabine",-0.267,0.197,0.764,0.000572,3.66,0.000256,4.06E-4,0.224,"0/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["ATAD5","Prexasertib",0.733,{"v":3.05e-05,"d":"3.05E-05"},-0.33,0.211,-3.66,0.000256,4.06E-4,0.224,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ANXA11","Cytarabine",-0.509,0.00938,0.615,0.0112,3.66,0.000256,0.000407,0.224,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["LAT2","Ribociclib",-0.592,0.00184,0.62,0.0105,4.01,{"v":5.95e-05,"d":"5.95E-05"},0.000151,0.224,"-/+","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["ORAI1","Cytarabine",-0.601,1.48E-3,0.666,0.00488,4.28,{"v":1.85e-05,"d":"1.85E-05"},{"v":6.38e-05,"d":"6.38E-05"},0.224,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["OIP5","Etoposide",0.304,0.14,-0.829,{"v":7.31e-05,"d":"7.31E-05"},-4.28,{"v":1.87e-05,"d":"1.87E-05"},{"v":6.38e-05,"d":"6.38E-05"},0.224,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["PDXK","AZD_5438",-0.468,0.0184,0.757,0.000685,4.28,{"v":1.89e-05,"d":"1.89E-05"},{"v":6.43e-05,"d":"6.43E-05"},0.224,"-/+","CDK1, 2, 9 inhibitor","CDK1;CDK2;CDK9","Kinase inhibitor"]
["SNUPN","Megestrol_acetate",0.446,0.0254,-0.728,1.39E-3,-4.01,{"v":5.97e-05,"d":"5.97E-05"},1.45E-4,0.224,"+/-","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["TIGD2","Bafetinib",0.129,0.537,-0.855,{"v":2.47e-05,"d":"2.47E-05"},-4.01,{"v":6e-05,"d":"6.00E-05"},1.45E-4,0.224,"0/-","ABL, Lyn inhibitor","ABL1;LYN","Kinase inhibitor"]
["SLC35B2","Temsirolimus",-0.57,0.00293,0.637,0.00791,4.01,{"v":6.18e-05,"d":"6.18E-05"},0.000148,0.224,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["TMEM192","ABT_751",-0.557,0.00386,0.649,0.00656,4,{"v":6.21e-05,"d":"6.21E-05"},0.000149,0.224,"-/+","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["SIRT1","Gemcitabine",0.593,1.8E-3,-0.616,0.011,-4,{"v":6.22e-05,"d":"6.22E-05"},0.000149,0.224,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["TNFAIP8L2","Cytarabine",-0.566,0.0032,0.641,0.0075,4,{"v":6.23e-05,"d":"6.23E-05"},0.00015,0.224,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["TBC1D31","Tivozanib",0.746,{"v":1.9e-05,"d":"1.90E-05"},-0.412,0.113,-4,{"v":6.23e-05,"d":"6.23E-05"},0.00015,0.224,"+/0","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["TMEM39B","Triapine",0.843,{"v":1.2e-07,"d":"1.20E-07"},-0.165,0.541,-4,{"v":6.32e-05,"d":"6.32E-05"},0.000151,0.224,"+/0","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["STX7","Navitoclax",0.499,0.0111,-0.691,0.00301,-4,{"v":6.37e-05,"d":"6.37E-05"},0.000152,0.224,"+/-","Bcl-2,Bcl-XL inhibitor","BCL2;BCL2L2;BAD;BCL2L1;MCL1","Apoptotic modulator"]
["TMEM219","ODM_201",-0.617,1.01E-3,0.59,0.0161,4,{"v":6.37e-05,"d":"6.37E-05"},0.000152,0.224,"-/+","AR antagonist","AR","Hormone therapy"]
["SGO2","Cytarabine",0.746,{"v":1.88E-5,"d":"1.88E-05"},-0.409,0.116,-4,{"v":6.45e-05,"d":"6.45E-05"},0.000153,0.224,"+/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["SIGIRR","Cytarabine.Idarubicin",-0.601,1.49E-3,0.606,0.0128,3.99,{"v":6.5e-05,"d":"6.50E-05"},1.54E-4,0.224,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["SUGP1","Cytarabine",0.457,0.0216,-0.718,1.73E-3,-3.99,{"v":6.51e-05,"d":"6.51E-05"},1.54E-4,0.224,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["SH3BP2","Danusertib",-0.572,2.82E-3,0.633,0.00847,3.99,{"v":6.52e-05,"d":"6.52E-05"},1.54E-4,0.224,"-/+","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["TIAM1","NVP_LCL161",-0.301,0.144,0.796,0.000228,3.99,{"v":6.55e-05,"d":"6.55E-05"},1.54E-4,0.224,"0/+","IAPs, SMAC mimetic","XIAP;BIRC2","Apoptotic modulator"]
["TMEM161A","Tamatinib",0.55,0.00443,-0.651,0.00627,-3.99,{"v":6.64e-05,"d":"6.64E-05"},1.55E-4,0.224,"+/-","SYK inhibitor","SYK","Kinase inhibitor"]
["TDP2","Clofarabine",0.495,0.0118,-0.692,0.003,-3.99,{"v":6.73e-05,"d":"6.73E-05"},1.56E-4,0.224,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["TMCC1","A_1210477",0.379,0.0615,-0.759,0.000643,-3.99,{"v":6.74e-05,"d":"6.74E-05"},1.56E-4,0.224,"0/-","MCL-1 inhibitor","MCL1","Apoptotic modulator"]
["SOS1","Dovitinib",-0.379,0.0614,0.759,0.000656,3.98,{"v":6.88e-05,"d":"6.88E-05"},0.000157,0.224,"0/+","FGFR inhibitor","FGFR1;FGFR3;KIT;FLT3;FLT4","Kinase inhibitor"]
["STRIP1","Topotecan",-0.498,0.0112,0.688,0.00319,3.98,{"v":6.9e-05,"d":"6.90E-05"},0.000158,0.224,"-/+","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["SPTBN2","Itraconazole",0.255,0.219,-0.812,1.35E-4,-3.98,{"v":6.91e-05,"d":"6.91E-05"},0.000158,0.224,"0/-","antifungal, hedgehog signaling inhibitor","CYP51A1;CYP3A4","Other"]
["SKA1","Prexasertib",0.746,{"v":1.9e-05,"d":"1.90E-05"},-0.405,0.12,-3.98,{"v":6.91e-05,"d":"6.91E-05"},0.000158,0.224,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["SRPRA","Finasteride",0.548,0.00461,-0.651,6.3E-3,-3.98,{"v":6.91e-05,"d":"6.91E-05"},0.000158,0.224,"+/-","type II 5-alpha reductase inhibitor","SRD5A2","Hormone therapy"]
["TRAPPC6B","Fostamatinib",-0.419,0.0369,0.766,0.00054,4.17,{"v":3.09e-05,"d":"3.09E-05"},{"v":7.96e-05,"d":"7.96E-05"},0.224,"-/+","SYK inhibitor","SYK","Kinase inhibitor"]
["USP16","Clofarabine",0.469,0.0181,-0.739,1.07E-3,-4.17,{"v":3.11e-05,"d":"3.11E-05"},{"v":8.01e-05,"d":"8.01E-05"},0.224,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["UNC119","Alpelisib",0.479,0.0155,-0.733,1.24E-3,-4.16,{"v":3.13e-05,"d":"3.13E-05"},{"v":8.11e-05,"d":"8.11E-05"},0.224,"+/-","PI3Kalpha selective inhibitor","PIK3CA","Kinase inhibitor"]
["VPS13B","AMG_925",0.719,{"v":5.1E-5,"d":"5.10E-05"},-0.501,0.0481,-4.16,{"v":3.13e-05,"d":"3.13E-05"},{"v":8.14E-5,"d":"8.14E-05"},0.224,"+/-","FLT3, CDK4 inhibitor","FLT3;CDK4","Kinase inhibitor"]
["ZNF516","Axitinib",0.471,0.0174,-0.737,0.00112,-4.16,{"v":3.14e-05,"d":"3.14E-05"},{"v":8.14E-5,"d":"8.14E-05"},0.224,"+/-","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["ZNF710","Filanesib",-0.51,0.00919,0.713,0.00194,4.16,{"v":3.16e-05,"d":"3.16E-05"},{"v":8.14E-5,"d":"8.14E-05"},0.224,"-/+","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["ZIK1","Vidofludimus",0.386,0.057,-0.781,3.57E-4,-4.16,{"v":3.24e-05,"d":"3.24E-05"},{"v":8.21e-05,"d":"8.21E-05"},0.224,"0/-","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["USP22","GSK_461364",0.637,6.11E-4,-0.604,0.0132,-4.15,{"v":3.27e-05,"d":"3.27E-05"},{"v":8.41e-05,"d":"8.41E-05"},0.224,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["VAT1L","Ribociclib",0.0103,0.961,0.898,{"v":2.32e-06,"d":"2.32E-06"},4.15,{"v":3.3e-05,"d":"3.30E-05"},{"v":8.49e-05,"d":"8.49E-05"},0.224,"0/+","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["ZNF592","Vinflunine",-0.42,0.0367,0.763,0.000581,4.15,{"v":3.34e-05,"d":"3.34E-05"},{"v":8.51e-05,"d":"8.51E-05"},0.224,"-/+","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["UBE2E2","PIM_447",0.576,0.00256,-0.66,0.00542,-4.14,{"v":3.42e-05,"d":"3.42E-05"},{"v":8.59e-05,"d":"8.59E-05"},0.224,"+/-","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["ZDHHC17","RO5126766",0.483,0.0145,-0.725,1.47E-3,-4.13,{"v":3.57E-5,"d":"3.57E-05"},{"v":8.69e-05,"d":"8.69E-05"},0.224,"+/-","dual RAF and MEK inhibitor","RAF1;BRAF;MAP2K1;MAP2K2","Kinase inhibitor"]
["WDR41","Altiratinib",-0.421,0.0363,0.76,0.000628,4.13,{"v":3.59e-05,"d":"3.59E-05"},{"v":8.99e-05,"d":"8.99E-05"},0.224,"-/+","MET, Tie-2 inhibitor","MET;NTRK1;NTRK3;NTRK2;TEK;FLT3;KIT;KDR","Kinase inhibitor"]
["UNC93B1","PF_03758309",-0.36,0.0775,0.789,0.000279,4.13,{"v":3.6e-05,"d":"3.60E-05"},{"v":9.04e-05,"d":"9.04E-05"},0.224,"0/+","PAK4 inhibitor","PAK4","Kinase inhibitor"]
["UBASH3A","Oxaliplatin",-0.366,0.0719,0.786,0.000307,4.13,{"v":3.64e-05,"d":"3.64E-05"},{"v":9.09E-5,"d":"9.09E-05"},0.224,"0/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["USP13","Topotecan",0.461,0.0203,-0.738,0.0011,-4.13,{"v":3.65E-5,"d":"3.65E-05"},{"v":9.16e-05,"d":"9.16E-05"},0.224,"+/-","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["WASHC5","Pemetrexed",-0.516,0.00824,0.703,0.00239,4.13,{"v":3.66e-05,"d":"3.66E-05"},{"v":9.21e-05,"d":"9.21E-05"},0.224,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["ZHX3","Digoxin",-0.59,1.89E-3,0.644,0.00707,4.13,{"v":3.67e-05,"d":"3.67E-05"},{"v":9.21e-05,"d":"9.21E-05"},0.224,"-/+","Cardiac glycoside","ATP1A1;ITGB1;ITGB3;ITGA3;ITGA1","Other"]
["UBASH3A","Idarubicin",-0.441,0.0275,0.749,0.000844,4.13,{"v":3.69e-05,"d":"3.69E-05"},{"v":9.21e-05,"d":"9.21E-05"},0.224,"-/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["ZNF646","Methotrexate",0.177,0.397,-0.852,{"v":2.82e-05,"d":"2.82E-05"},-4.12,{"v":3.77e-05,"d":"3.77E-05"},{"v":9.21e-05,"d":"9.21E-05"},0.224,"0/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["TUBB","CCT196969",-0.671,0.000239,0.557,0.0251,4.12,{"v":3.8e-05,"d":"3.80E-05"},{"v":9.39e-05,"d":"9.39E-05"},0.224,"-/+","pan-RAF, Src inhibitor","RAF1;BRAF;SRC;LCK","Kinase inhibitor"]
["WDR59","Resminostat",-0.026,0.902,0.888,{"v":4.28e-06,"d":"4.28E-06"},4.12,{"v":3.83e-05,"d":"3.83E-05"},{"v":9.51e-05,"d":"9.51E-05"},0.224,"0/+","HDAC1, 3, 6 inhibitor","HDAC1;HDAC3;HDAC6","Differentiating.epigenetic modifier"]
["TXNDC9","Topotecan",0.593,1.8E-3,-0.64,0.00756,-4.12,{"v":3.84e-05,"d":"3.84E-05"},{"v":9.51e-05,"d":"9.51E-05"},0.224,"+/-","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["TPX2","Cisplatin",0.532,0.00618,-0.689,0.00317,-4.11,{"v":3.91e-05,"d":"3.91E-05"},{"v":9.54e-05,"d":"9.54E-05"},0.224,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["XRCC5","PF_00477736",0.107,0.612,-0.869,{"v":1.22E-5,"d":"1.22E-05"},-4.11,{"v":3.95e-05,"d":"3.95E-05"},{"v":9.61e-05,"d":"9.61E-05"},0.224,"0/-","CHEK1 inhibitor","CHEK1;KDR;FLT3;YES1;CHEK2","Kinase inhibitor"]
["ZNF362","BMS863233",-0.344,0.0921,0.793,0.000249,4.11,{"v":3.97e-05,"d":"3.97E-05"},{"v":9.69e-05,"d":"9.69E-05"},0.224,"0/+","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["ZNF507","Alisertib",0.738,{"v":2.54e-05,"d":"2.54E-05"},-0.455,0.0767,-4.11,{"v":3.99e-05,"d":"3.99E-05"},{"v":9.71e-05,"d":"9.71E-05"},0.224,"+/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["TSPO","Temsirolimus",-0.184,0.377,0.848,{"v":3.28e-05,"d":"3.28E-05"},4.11,{"v":4e-05,"d":"4.00E-05"},{"v":9.79e-05,"d":"9.79E-05"},0.224,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["TPX2","Niraparib",0.563,0.0034,-0.664,0.00503,-4.11,{"v":4.01e-05,"d":"4.01E-05"},{"v":9.86e-05,"d":"9.86E-05"},0.224,"+/-","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["TONSL","Pemetrexed",0.688,1.45E-4,-0.532,0.0341,-4.1,{"v":4.04e-05,"d":"4.04E-05"},{"v":9.86e-05,"d":"9.86E-05"},0.224,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["TRIM11","Niraparib",0.41,0.0416,-0.761,0.000612,-4.1,{"v":4.07E-5,"d":"4.07E-05"},{"v":9.94e-05,"d":"9.94E-05"},0.224,"+/-","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["TRIM11","Prexasertib",0.75,{"v":1.58e-05,"d":"1.58E-05"},-0.432,0.0947,-4.1,{"v":4.07E-5,"d":"4.07E-05"},{"v":9.94e-05,"d":"9.94E-05"},0.224,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ZSCAN21","Ipatasertib",0.553,0.00416,-0.67,0.00451,-4.1,{"v":4.18E-5,"d":"4.18E-05"},{"v":9.94e-05,"d":"9.94E-05"},0.224,"+/-","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["ZZEF1","RGFP966",-0.432,0.0311,0.749,0.00085,4.09,{"v":4.25e-05,"d":"4.25E-05"},1.01E-4,0.224,"-/+","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["UBXN1","Megestrol_acetate",-0.361,0.0761,0.783,3.39E-4,4.09,{"v":4.35E-5,"d":"4.35E-05"},1.03E-4,0.224,"0/+","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["ZADH2","Fludarabine",-0.466,0.0188,0.728,1.4E-3,4.08,{"v":4.41e-05,"d":"4.41E-05"},1.05E-4,0.224,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["WASHC4","Raltitrexed",-0.408,0.0427,0.76,0.000642,4.08,{"v":4.43e-05,"d":"4.43E-05"},1.07E-4,0.224,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["WSB1","Perifosine",-0.0716,0.734,0.876,{"v":8.83e-06,"d":"8.83E-06"},4.08,{"v":4.44e-05,"d":"4.44E-05"},1.07E-4,0.224,"0/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["ZNF480","Pazopanib",0.529,0.00654,-0.685,0.00338,-4.08,{"v":4.45e-05,"d":"4.45E-05"},1.07E-4,0.224,"+/-","VEGFR inhibitor","FLT1;KDR;FLT4;KIT;PDGFRA;PDGFRB;CSF1R;FGFR3;ITK","Kinase inhibitor"]
["USP1","Pemetrexed",0.756,{"v":1.24E-5,"d":"1.24E-05"},-0.415,0.11,-4.08,{"v":4.46E-5,"d":"4.46E-05"},1.07E-4,0.224,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["VKORC1L1","BX_912",-0.592,1.83E-3,0.633,0.00845,4.08,{"v":4.49E-5,"d":"4.49E-05"},1.08E-4,0.224,"-/+","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["ZNF398","AZD3965",-0.203,0.33,0.84,{"v":4.66e-05,"d":"4.66E-05"},4.08,{"v":4.51e-05,"d":"4.51E-05"},1.08E-4,0.224,"0/+","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["ZPR1","Onalespib",0.249,0.23,-0.825,{"v":8.47e-05,"d":"8.47E-05"},-4.08,{"v":4.6E-5,"d":"4.60E-05"},1.08E-4,0.224,"0/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["TRAPPC10","RGFP966",-0.588,0.00201,0.635,0.00818,4.07,{"v":4.68e-05,"d":"4.68E-05"},1.1E-4,0.224,"-/+","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["ZNF101","Vinorelbine",0.465,0.0193,-0.726,0.00144,-4.07,{"v":4.68e-05,"d":"4.68E-05"},1.11E-4,0.224,"+/-","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["WASHC2A","Cytarabine",-0.482,0.0147,0.716,1.82E-3,4.07,{"v":4.69e-05,"d":"4.69E-05"},1.11E-4,0.224,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ZNF644","Cabazitaxel",0.636,0.000641,-0.587,0.0168,-4.07,{"v":4.7e-05,"d":"4.70E-05"},1.11E-4,0.224,"+/-","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["ZNF518B","VER_155008",0.621,0.000928,-0.603,0.0135,-4.07,{"v":4.7e-05,"d":"4.70E-05"},1.11E-4,0.224,"+/-","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["WSB1","Vinblastine",-0.142,0.498,0.856,{"v":2.29e-05,"d":"2.29E-05"},4.07,{"v":4.76e-05,"d":"4.76E-05"},1.11E-4,0.224,"0/+","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["USP37","Cytarabine",0.591,0.00187,-0.63,0.00886,-4.06,{"v":4.88E-5,"d":"4.88E-05"},1.13E-4,0.224,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ZNRD2","Raltitrexed",0.763,{"v":9.29e-06,"d":"9.29E-06"},-0.395,0.13,-4.06,{"v":4.92e-05,"d":"4.92E-05"},0.000114,0.224,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["UBR5","Cabazitaxel",0.608,0.00126,-0.612,0.0117,-4.06,{"v":5.01e-05,"d":"5.01E-05"},1.15E-4,0.224,"+/-","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["UBASH3A","Doxorubicin",-0.456,0.022,0.729,0.00137,4.05,{"v":5.05e-05,"d":"5.05E-05"},1.16E-4,0.224,"-/+","Topoisomerase II inhibitor","TOP2A;NOLC1","Conv.Chemo"]
["VKORC1L1","Prexasertib",-0.809,{"v":9.6e-07,"d":"9.60E-07"},0.284,0.286,4.05,{"v":5.08e-05,"d":"5.08E-05"},1.16E-4,0.224,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ZFAND6","Imiquimod",-0.272,0.189,0.814,1.25E-4,4.05,{"v":5.1E-5,"d":"5.10E-05"},1.17E-4,0.224,"0/+","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["TXNRD3","Azacitidine",-0.421,0.0361,0.748,0.000868,4.05,{"v":5.13E-5,"d":"5.13E-05"},1.17E-4,0.224,"-/+","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["ZNF771","Enzalutamide",-0.158,0.45,0.85,{"v":3.02e-05,"d":"3.02E-05"},4.05,{"v":5.13E-5,"d":"5.13E-05"},1.17E-4,0.224,"0/+","AR antagonist","AR","Hormone therapy"]
["USP33","AZD7762",0.683,0.00017,-0.524,0.0373,-4.05,{"v":5.19e-05,"d":"5.19E-05"},1.17E-4,0.224,"+/-","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["ZCCHC7","Mitomycin_C",0.213,0.306,-0.833,{"v":6.09e-05,"d":"6.09E-05"},-4.05,{"v":5.2e-05,"d":"5.20E-05"},0.000119,0.224,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["ZNF32","Enzalutamide",-0.704,{"v":8.7e-05,"d":"8.70E-05"},0.494,0.0519,4.05,{"v":5.21e-05,"d":"5.21E-05"},0.000119,0.224,"-/0","AR antagonist","AR","Hormone therapy"]
["WIPF1","BIIB021",-0.464,0.0195,0.722,1.58E-3,4.04,{"v":5.26e-05,"d":"5.26E-05"},0.000119,0.224,"-/+","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["ZADH2","AT_101",-0.462,0.0199,0.722,1.58E-3,4.04,{"v":5.37e-05,"d":"5.37E-05"},1.2E-4,0.224,"-/+","pan Bcl-2 family inhibitor","BCL2;BCL2L1;MCL1","Apoptotic modulator"]
["ZFYVE26","Tozasertib",-0.775,{"v":5.43e-06,"d":"5.43E-06"},0.363,0.167,4.04,{"v":5.38E-5,"d":"5.38E-05"},1.22E-4,0.224,"-/0","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["TXNDC17","Onalespib",0.729,{"v":3.52e-05,"d":"3.52E-05"},-0.45,0.08,-4.04,{"v":5.39e-05,"d":"5.39E-05"},1.22E-4,0.224,"+/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["USP10","SN_38",0.711,{"v":6.81e-05,"d":"6.81E-05"},-0.48,0.0597,-4.04,{"v":5.41E-5,"d":"5.41E-05"},1.22E-4,0.224,"+/0","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["UPF3A","Glesatinib",-0.561,0.00354,0.651,0.00626,4.04,{"v":5.44e-05,"d":"5.44E-05"},0.000123,0.224,"-/+","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["TXNDC9","Amsacrine",0.65,0.000439,-0.562,0.0234,-4.03,{"v":5.49E-5,"d":"5.49E-05"},0.000124,0.224,"+/-","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["ZNF654","Tipifarnib",-0.38,0.0611,0.766,0.00054,4.03,{"v":5.53e-05,"d":"5.53E-05"},0.000124,0.224,"0/+","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["UFL1","VS_4718",0.432,0.031,-0.739,1.08E-3,-4.03,{"v":5.57e-05,"d":"5.57E-05"},0.000124,0.224,"+/-","FAK inhibitor","PTK2","Kinase inhibitor"]
["WDR37","Carboplatin",-0.382,0.0593,0.765,5.62E-4,4.03,{"v":5.57e-05,"d":"5.57E-05"},1.25E-4,0.224,"0/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["ZC3HAV1L","Uprosertib",0.403,0.0457,-0.754,0.000744,-4.03,{"v":5.61e-05,"d":"5.61E-05"},1.25E-4,0.224,"+/-","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["ZNF101","Paclitaxel",0.437,0.0288,-0.735,1.17E-3,-4.03,{"v":5.62e-05,"d":"5.62E-05"},1.25E-4,0.224,"+/-","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["TXNDC17","Fludarabine",0.509,0.00929,-0.689,3.13E-3,-4.03,{"v":5.65e-05,"d":"5.65E-05"},1.25E-4,0.224,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["UNC13D","Danusertib",-0.235,0.258,0.824,{"v":8.78e-05,"d":"8.78E-05"},4.02,{"v":5.71e-05,"d":"5.71E-05"},1.26E-4,0.224,"0/+","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["ZNF507","GSK_1070916",0.637,0.000624,-0.575,0.0197,-4.02,{"v":5.71e-05,"d":"5.71E-05"},1.27E-4,0.224,"+/-","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["WASHC4","Clofarabine",-0.262,0.206,0.814,0.000124,4.02,{"v":5.78e-05,"d":"5.78E-05"},1.27E-4,0.224,"0/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["BRWD1","Rigosertib",0.528,0.00666,-0.599,0.0143,-3.66,0.000257,0.00041,0.225,"+/-","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["ATP5F1A","Paclitaxel",-0.24,0.249,0.775,0.000416,3.65,0.000258,0.000411,0.225,"0/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["BUB1","SN_38",0.617,0.00102,-0.506,0.0454,-3.65,0.000259,0.000411,0.225,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["C1orf112","Eribulin",0.726,{"v":4.01e-05,"d":"4.01E-05"},-0.343,0.193,-3.65,2.61E-4,0.000412,0.225,"+/0","Mitotic inhibitor, microtubule depolymerizer","TUBB1","Conv.Chemo"]
["AEBP2","Resminostat",0.419,0.0373,-0.681,0.00367,-3.65,2.61E-4,0.000414,0.225,"+/-","HDAC1, 3, 6 inhibitor","HDAC1;HDAC3;HDAC6","Differentiating.epigenetic modifier"]
["APLF","Masitinib",0.374,0.0657,-0.709,0.00212,-3.65,2.61E-4,4.15E-4,0.225,"0/-","KIT inhibitor","KIT","Kinase inhibitor"]
["C12orf45","Raltitrexed",0.637,0.000612,-0.48,0.0598,-3.65,0.000262,4.17E-4,0.225,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["BCAT2","MK_8745",-0.448,0.0248,0.661,0.00529,3.65,0.000262,4.17E-4,0.225,"-/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["CADM4","Ribociclib",0.635,0.000648,-0.483,0.0581,-3.65,0.000262,0.000418,0.225,"+/0","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["ABCB8","Cladribine",0.23,0.27,-0.779,0.000376,-3.65,2.63E-4,0.000419,0.225,"0/-","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["BLOC1S3","Cerdulatinib",-0.204,0.327,0.789,0.000278,3.65,2.63E-4,0.000419,0.225,"0/+","JAK, SYK inhibitor","JAK1;JAK2;JAK3;TYK2;SYK","Kinase inhibitor"]
["AC091230.1","BX_912",-0.29,0.16,0.752,0.000772,3.65,2.63E-4,0.000419,0.225,"0/+","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["BAK1","BX_912",-0.509,0.00942,0.614,0.0114,3.65,0.000265,0.000419,0.225,"-/+","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["ADD3","Paclitaxel",-0.156,0.456,0.807,0.000158,3.65,0.000265,0.000419,0.225,"0/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["ARHGAP25","Cytarabine",-0.695,1.17E-4,0.396,0.129,3.65,0.000265,0.000419,0.225,"-/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["CHAF1B","Cytarabine.Idarubicin",0.407,0.0432,-0.806,1.64E-4,-4.42,{"v":9.71e-06,"d":"9.71E-06"},{"v":4.88E-5,"d":"4.88E-05"},0.225,"+/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["CHMP5","BX_912",0.449,0.0243,-0.786,0.000302,-4.42,{"v":9.91E-6,"d":"9.91E-06"},{"v":4.93e-05,"d":"4.93E-05"},0.225,"+/-","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["LGALS3BP","Gemcitabine",-0.518,0.00803,0.68,0.00374,4.01,{"v":6.08e-05,"d":"6.08E-05"},0.000153,0.225,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["KIF4A","Gemcitabine",0.534,0.00593,-0.667,0.0048,-4,{"v":6.22e-05,"d":"6.22E-05"},1.55E-4,0.225,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["IQSEC1","Acitretin",0.494,0.0122,-0.696,0.00274,-4,{"v":6.23e-05,"d":"6.23E-05"},1.55E-4,0.225,"+/-","Retinoic acid receptor agonist","RARA;RARB;RXRA;RXRB;RXRG","Differentiating.epigenetic modifier"]
["INO80D","MK_8745",-0.154,0.463,0.847,{"v":3.49e-05,"d":"3.49E-05"},4,{"v":6.26e-05,"d":"6.26E-05"},1.55E-4,0.225,"0/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["ICAM3","8_amino_adenosine",-0.21,0.313,0.829,{"v":7.07e-05,"d":"7.07E-05"},4,{"v":6.28e-05,"d":"6.28E-05"},1.56E-4,0.225,"0/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["LAT2","CPI_0610",-0.701,{"v":9.58e-05,"d":"9.58E-05"},0.486,0.0563,4,{"v":6.31e-05,"d":"6.31E-05"},1.56E-4,0.225,"-/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["KANK2","Trametinib",0.461,0.0204,-0.716,1.8E-3,-4,{"v":6.38e-05,"d":"6.38E-05"},0.000157,0.225,"+/-","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["LSM12","GSK_1070916",0.275,0.183,-0.806,1.63E-4,-4,{"v":6.41E-5,"d":"6.41E-05"},0.000158,0.225,"0/-","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["KPNA3","AZD3965",0.467,0.0186,-0.712,1.97E-3,-4,{"v":6.45e-05,"d":"6.45E-05"},0.00016,0.225,"+/-","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["LRRC1","Litronesib",0.499,0.0112,-0.691,0.00303,-4,{"v":6.45e-05,"d":"6.45E-05"},0.00016,0.225,"+/-","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["JRKL","Nintedanib",0.0926,0.66,-0.863,{"v":1.69e-05,"d":"1.69E-05"},-3.99,{"v":6.5e-05,"d":"6.50E-05"},0.000161,0.225,"0/-","VEGFR, PDGFR, FGFR inhibitor","FGFR1;FGFR2;FLT1;FLT4;KDR;PDGFRA;PDGFRB","Kinase inhibitor"]
["ITIH2","Prexasertib",-0.783,{"v":3.8E-6,"d":"3.80E-06"},0.332,0.209,3.99,{"v":6.5e-05,"d":"6.50E-05"},0.000161,0.225,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["MCRIP1","CC_223",0.461,0.0205,-0.715,1.83E-3,-3.99,{"v":6.56e-05,"d":"6.56E-05"},0.000162,0.225,"+/-","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["METTL16","Birinapant",0.316,0.124,-0.789,0.00028,-3.99,{"v":6.59e-05,"d":"6.59E-05"},0.000162,0.225,"0/-","IAPs, SMAC mimetic","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["LRRK1","Tamatinib",-0.412,0.0409,0.743,0.000965,3.99,{"v":6.62e-05,"d":"6.62E-05"},1.63E-4,0.225,"-/+","SYK inhibitor","SYK","Kinase inhibitor"]
["ITPR3","Agerafenib_CEP_32496",-0.569,2.99E-3,0.635,8.26E-3,3.99,{"v":6.64e-05,"d":"6.64E-05"},1.64E-4,0.225,"-/+","BRAF(V600E) inhibitor","BRAF;RAF1;KIT;RET;LCK;ABL1;PDGFRB;CSF1R;MET;EGFR;KDR;EPHA2","Kinase inhibitor"]
["MBOAT7","AZD_5438",-0.232,0.264,0.821,{"v":9.83e-05,"d":"9.83E-05"},3.99,{"v":6.66e-05,"d":"6.66E-05"},1.64E-4,0.225,"0/+","CDK1, 2, 9 inhibitor","CDK1;CDK2;CDK9","Kinase inhibitor"]
["IL6ST","Uprosertib",-0.35,0.0865,0.774,4.35E-4,3.99,{"v":6.67e-05,"d":"6.67E-05"},1.64E-4,0.225,"0/+","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["KNL1","Gemcitabine",0.743,{"v":2.1e-05,"d":"2.10E-05"},-0.412,0.113,-3.99,{"v":6.68e-05,"d":"6.68E-05"},1.64E-4,0.225,"+/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["KDSR","Nelarabine",-0.264,0.203,0.809,1.47E-4,3.99,{"v":6.69E-5,"d":"6.69E-05"},1.65E-4,0.225,"0/+","Antimetabolite, Nucleoside analog, DNA, RNA synth inhibitor","DNA","Conv.Chemo"]
["KHNYN","LY_2874455",-0.556,0.00393,0.646,0.0069,3.99,{"v":6.72e-05,"d":"6.72E-05"},1.66E-4,0.225,"-/+","FGFR inhibitor","FGFR1;FGFR2;FGFR3","Kinase inhibitor"]
["MCM10","Raltitrexed",0.652,0.000414,-0.548,0.0281,-3.98,{"v":6.77e-05,"d":"6.77E-05"},1.66E-4,0.225,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["KMO","AMG319",0.428,0.0327,-0.733,1.24E-3,-3.98,{"v":6.87e-05,"d":"6.87E-05"},0.000168,0.225,"+/-","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["KIF2C","IOX_1",0.394,0.0512,-0.75,0.000813,-3.97,{"v":7.05e-05,"d":"7.05E-05"},0.000171,0.225,"0/-","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["LDAH","IOX_2",0.0963,0.647,-0.86,{"v":1.93e-05,"d":"1.93E-05"},-3.97,{"v":7.05e-05,"d":"7.05E-05"},0.000172,0.225,"0/-","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["MROH1","BX_912",-0.314,0.126,0.787,0.000293,3.97,{"v":7.08E-5,"d":"7.08E-05"},0.000172,0.225,"0/+","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["METTL5","GSK_1070916",0.395,0.051,-0.75,0.000822,-3.97,{"v":7.09e-05,"d":"7.09E-05"},0.000172,0.225,"0/-","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["IDS","8_amino_adenosine",-0.34,0.0966,0.776,4.08E-4,3.97,{"v":7.14e-05,"d":"7.14E-05"},0.000172,0.225,"0/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["MAVS","Cytarabine",-0.754,{"v":1.35e-05,"d":"1.35E-05"},0.386,0.139,3.97,{"v":7.15e-05,"d":"7.15E-05"},0.000172,0.225,"-/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["LIAS","Entinostat",-0.482,0.0147,0.698,2.64E-3,3.97,{"v":7.21e-05,"d":"7.21E-05"},1.73E-4,0.225,"-/+","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["LGALS3BP","Clofarabine",-0.442,0.027,0.723,1.56E-3,3.97,{"v":7.23e-05,"d":"7.23E-05"},1.73E-4,0.225,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["METTL17","Givinostat",-0.75,{"v":1.61e-05,"d":"1.61E-05"},0.394,0.131,3.97,{"v":7.25E-5,"d":"7.25E-05"},1.73E-4,0.225,"-/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC10","Differentiating.epigenetic modifier"]
["MIER2","Losmapimod",0.0775,0.713,-0.864,{"v":1.59E-5,"d":"1.59E-05"},-3.97,{"v":7.33e-05,"d":"7.33E-05"},1.76E-4,0.225,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["ILVBL","GSK923295",-0.321,0.117,0.783,0.000331,3.97,{"v":7.33e-05,"d":"7.33E-05"},1.76E-4,0.225,"0/+","CENP-E inhibitor","CENPE","Kinesin inhibitor"]
["MGAT1","MST_312",-0.238,0.252,0.816,1.17E-4,3.97,{"v":7.34e-05,"d":"7.34E-05"},1.76E-4,0.225,"0/+","Telomerase inhibitor","TERT","Other"]
["LPCAT4","Idarubicin",-0.682,0.000171,0.503,0.047,3.96,{"v":7.34e-05,"d":"7.34E-05"},1.76E-4,0.225,"-/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["MIS18A","Cisplatin",0.361,0.0761,-0.765,0.000551,-3.96,{"v":7.34e-05,"d":"7.34E-05"},1.76E-4,0.225,"0/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["MIS18A","Clofarabine",0.596,1.66E-3,-0.604,0.0133,-3.96,{"v":7.39e-05,"d":"7.39E-05"},1.76E-4,0.225,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["KIF4A","OSU_03012",0.556,0.00392,-0.641,0.0075,-3.96,{"v":7.43e-05,"d":"7.43E-05"},0.000177,0.225,"+/-","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["MAP3K3","IOX_1",-0.482,0.0146,0.696,0.00275,3.96,{"v":7.48e-05,"d":"7.48E-05"},0.000177,0.225,"-/+","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["PSMG1","Cytarabine.Idarubicin",0.294,0.154,-0.84,{"v":4.61e-05,"d":"4.61E-05"},-4.36,{"v":1.31E-5,"d":"1.31E-05"},{"v":4.64e-05,"d":"4.64E-05"},0.225,"0/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["RELL1","Valrubicin",-0.454,0.0226,0.773,0.000442,4.34,{"v":1.43E-5,"d":"1.43E-05"},{"v":4.88E-5,"d":"4.88E-05"},0.225,"-/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["PTOV1","Idarubicin",0.539,5.45E-3,-0.724,0.00152,-4.34,{"v":1.43E-5,"d":"1.43E-05"},{"v":4.88E-5,"d":"4.88E-05"},0.225,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["PTBP1","Onalespib",-0.746,{"v":1.87e-05,"d":"1.87E-05"},0.503,0.0469,4.34,{"v":1.44e-05,"d":"1.44E-05"},{"v":4.96e-05,"d":"4.96E-05"},0.225,"-/+","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["RDH14","AT_406",0.608,0.00128,-0.67,0.00455,-4.33,{"v":1.49E-5,"d":"1.49E-05"},{"v":5.11e-05,"d":"5.11E-05"},0.225,"+/-","XIAP, cIAP1, cIAP2 inhibitor","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["PPP1CA","EPZ015666",-0.8,{"v":1.55E-6,"d":"1.55E-06"},0.393,0.133,4.33,{"v":1.49E-5,"d":"1.49E-05"},{"v":5.11e-05,"d":"5.11E-05"},0.225,"-/0","PRMT5 inhibitor","PRMT5","Differentiating.epigenetic modifier"]
["RAD51","SN_38",0.622,0.000908,-0.657,0.00573,-4.33,{"v":1.5E-5,"d":"1.50E-05"},{"v":5.13E-5,"d":"5.13E-05"},0.225,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["PSMG1","Cytarabine",0.362,0.0752,-0.812,0.000132,-4.32,{"v":1.53e-05,"d":"1.53E-05"},{"v":5.21e-05,"d":"5.21E-05"},0.225,"0/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["RMDN2","Tucidinostat",0.528,0.00669,-0.728,0.00137,-4.32,{"v":1.53e-05,"d":"1.53E-05"},{"v":5.21e-05,"d":"5.21E-05"},0.225,"+/-","HDAC1, 2, 3 and 10 inhibitor","HDAC1;HDAC2;HDAC3;HDAC10","Differentiating.epigenetic modifier"]
["RUNX3","Birinapant",-0.351,0.0853,0.816,0.000114,4.32,{"v":1.54e-05,"d":"1.54E-05"},{"v":5.23e-05,"d":"5.23E-05"},0.225,"0/+","IAPs, SMAC mimetic","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["RAB15","Vandetanib",-0.0645,0.759,0.895,{"v":2.83E-6,"d":"2.83E-06"},4.32,{"v":1.55e-05,"d":"1.55E-05"},{"v":5.23e-05,"d":"5.23E-05"},0.225,"0/+","VEGFR, EGFR, RET inhibitor","KDR;FLT4;EGFR;RET","Kinase inhibitor"]
["RHOT2","Masitinib",-0.425,0.034,0.784,3.21E-4,4.32,{"v":1.57e-05,"d":"1.57E-05"},{"v":5.26e-05,"d":"5.26E-05"},0.225,"-/+","KIT inhibitor","KIT","Kinase inhibitor"]
["RBM15B","Losmapimod",0.42,0.0367,-0.787,0.000302,-4.32,{"v":1.59E-5,"d":"1.59E-05"},{"v":5.33e-05,"d":"5.33E-05"},0.225,"+/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["STK35","BMS863233",0.39,0.054,-0.753,0.000765,-3.98,{"v":7e-05,"d":"7.00E-05"},0.000161,0.225,"0/-","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["SRPRA","Fulvestrant",0.53,0.00647,-0.665,0.00498,-3.98,{"v":7.02e-05,"d":"7.02E-05"},0.000161,0.225,"+/-","Estrogen receptor antagonist","ESR1","Hormone therapy"]
["TDP2","Pemetrexed",0.522,0.00742,-0.67,0.00449,-3.98,{"v":7.03e-05,"d":"7.03E-05"},0.000161,0.225,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["SLC35B2","Ridaforolimus",-0.493,0.0123,0.691,0.00305,3.97,{"v":7.13e-05,"d":"7.13E-05"},1.63E-4,0.225,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SLC35F6","Prexasertib",-0.719,{"v":5.18e-05,"d":"5.18E-05"},0.45,0.0805,3.97,{"v":7.13e-05,"d":"7.13E-05"},1.63E-4,0.225,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["TLR1","8_amino_adenosine",-0.549,0.00446,0.648,0.00665,3.97,{"v":7.18e-05,"d":"7.18E-05"},1.63E-4,0.225,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["SLC35B2","AZD8055",-0.59,0.00193,0.612,0.0118,3.97,{"v":7.2e-05,"d":"7.20E-05"},1.63E-4,0.225,"-/+","mTOR inhibitor","MTOR","Kinase inhibitor"]
["SIDT2","Cytarabine.Idarubicin",-0.651,0.000429,0.545,0.0289,3.97,{"v":7.23e-05,"d":"7.23E-05"},1.63E-4,0.225,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["SFT2D3","Valrubicin",0.551,0.00432,-0.646,0.00688,-3.97,{"v":7.28e-05,"d":"7.28E-05"},1.65E-4,0.225,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["SSR1","Temsirolimus",-0.576,0.00257,0.623,0.00987,3.97,{"v":7.29e-05,"d":"7.29E-05"},1.65E-4,0.225,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SETD2","Exemestane",0.3,0.145,-0.793,0.000251,-3.97,{"v":7.3e-05,"d":"7.30E-05"},1.65E-4,0.225,"0/-","Aromatase inhibitor","CYP19A1","Hormone therapy"]
["SLC27A1","8_amino_adenosine",-0.527,0.00681,0.665,0.00498,3.96,{"v":7.36E-5,"d":"7.36E-05"},0.000167,0.225,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["SNX16","Dasatinib",0.721,{"v":4.76e-05,"d":"4.76E-05"},-0.442,0.0862,-3.96,{"v":7.5e-05,"d":"7.50E-05"},0.000168,0.225,"+/0","ABL, Src, Kit, EphR Inhibitor","ABL1","Kinase inhibitor"]
["SIDT2","RGFP966",-0.674,0.000219,0.513,0.0422,3.96,{"v":7.51e-05,"d":"7.51E-05"},0.000168,0.225,"-/+","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["TES","Quizartinib",0.779,{"v":4.4e-06,"d":"4.40E-06"},-0.329,0.214,-3.96,{"v":7.52e-05,"d":"7.52E-05"},0.000168,0.225,"+/0","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["SPN","Temsirolimus",-0.454,0.0226,0.714,1.9E-3,3.96,{"v":7.56e-05,"d":"7.56E-05"},0.000169,0.225,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SNX16","Bafetinib",0.735,{"v":2.86e-05,"d":"2.86E-05"},-0.418,0.107,-3.96,{"v":7.58e-05,"d":"7.58E-05"},0.000169,0.225,"+/0","ABL, Lyn inhibitor","ABL1;LYN","Kinase inhibitor"]
["TNFAIP8","Glasdegib",0.0851,0.686,-0.861,{"v":1.82e-05,"d":"1.82E-05"},-3.96,{"v":7.64E-5,"d":"7.64E-05"},0.00017,0.225,"0/-","Smo inhibitor","SMO","Hedgehog inhibitor"]
["SYF2","MK_8745",0.232,0.264,-0.817,1.13E-4,-3.95,{"v":7.68e-05,"d":"7.68E-05"},0.00017,0.225,"0/-","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["TSPYL1","VER_155008",0.431,0.0316,-0.738,0.0011,-4.02,{"v":5.79e-05,"d":"5.79E-05"},0.000129,0.225,"+/-","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["UBASH3A","SN_38",-0.262,0.205,0.813,0.000128,4.02,{"v":5.9e-05,"d":"5.90E-05"},0.000129,0.225,"0/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["ASAH1","WEHI_539",0.55,0.0044,-0.576,0.0195,-3.65,0.000267,0.000423,0.226,"+/-","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["BLM","Pemetrexed",0.535,0.00584,-0.59,0.0161,-3.64,0.000268,0.000423,0.226,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["AURKB","Clofarabine",0.633,0.00069,-0.484,0.0572,-3.64,0.000269,0.000423,0.226,"+/0","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["FARSA","Pemetrexed",0.715,{"v":5.86e-05,"d":"5.86E-05"},-0.522,0.0381,-4.22,{"v":2.42e-05,"d":"2.42E-05"},{"v":8.12e-05,"d":"8.12E-05"},0.226,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["GLCE","KU_60019",0.285,0.167,-0.828,{"v":7.34e-05,"d":"7.34E-05"},-4.22,{"v":2.43e-05,"d":"2.43E-05"},{"v":8.17e-05,"d":"8.17E-05"},0.226,"0/-","ATM inhibitor","ATM","Kinase inhibitor"]
["EIF3B","Pemetrexed",0.609,1.23E-3,-0.646,0.00684,-4.22,{"v":2.44E-5,"d":"2.44E-05"},{"v":8.17e-05,"d":"8.17E-05"},0.226,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["EIF4G2","Floxuridine",0.651,4.28E-4,-0.604,0.0133,-4.22,{"v":2.46e-05,"d":"2.46E-05"},{"v":8.25E-5,"d":"8.25E-05"},0.226,"+/-","Antimetabolite, Analog of 5-fluorouracil","TYMS","Conv.Chemo"]
["GNL3L","GSK_461364",0.451,0.0238,-0.757,0.000685,-4.22,{"v":2.49e-05,"d":"2.49E-05"},{"v":8.32e-05,"d":"8.32E-05"},0.226,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["FERMT3","Hydroxyurea",-0.411,0.0412,0.777,0.000401,4.21,{"v":2.51E-5,"d":"2.51E-05"},{"v":8.4e-05,"d":"8.40E-05"},0.226,"-/+","Antineoplastic agent","RRM1","Conv.Chemo"]
["GIT1","Fulvestrant",0.486,0.0137,-0.736,1.14E-3,-4.21,{"v":2.52e-05,"d":"2.52E-05"},{"v":8.42E-5,"d":"8.42E-05"},0.226,"+/-","Estrogen receptor antagonist","ESR1","Hormone therapy"]
["IL6ST","GSK_690693",-0.261,0.208,0.807,0.00016,3.96,{"v":7.56e-05,"d":"7.56E-05"},0.000179,0.226,"0/+","AKT, PKA, PKC inhibitor","AKT1;AKT2;AKT3;PRKCE;PRKCB;PRKCD;PRKCH;PRKCQ;PRKX;PRKG1","Kinase inhibitor"]
["INCENP","SN_38",0.652,4.15E-4,-0.541,0.0304,-3.96,{"v":7.59e-05,"d":"7.59E-05"},0.00018,0.226,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["KIAA0930","Mubritinib",-0.529,0.00655,0.661,0.00526,3.96,{"v":7.61e-05,"d":"7.61E-05"},0.00018,0.226,"-/+","HER2 inhibitor","ERBB2","Kinase inhibitor"]
["LARP4","VER_155008",0.627,0.000799,-0.57,0.0211,-3.96,{"v":7.63e-05,"d":"7.63E-05"},0.000181,0.226,"+/-","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["SLC25A20","Hydroxyurea",-0.202,0.334,0.827,{"v":7.8e-05,"d":"7.80E-05"},3.95,{"v":7.74e-05,"d":"7.74E-05"},0.000172,0.226,"0/+","Antineoplastic agent","RRM1","Conv.Chemo"]
["TNFAIP8","Seliciclib",0.446,0.0256,-0.718,1.75E-3,-3.95,{"v":7.78e-05,"d":"7.78E-05"},0.000172,0.226,"+/-","CDK2, 7, 9 inhibitor","CDK2;CDK1;CDK5;MAPK1;MAPK3","Kinase inhibitor"]
["TMEM131L","Cytarabine",0.544,0.0049,-0.647,0.00671,-3.95,{"v":7.88e-05,"d":"7.88E-05"},1.74E-4,0.226,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["THUMPD1","Brigatinib",-0.0852,0.686,0.861,{"v":1.89e-05,"d":"1.89E-05"},3.95,{"v":7.9e-05,"d":"7.90E-05"},1.74E-4,0.226,"0/+","ALK inhibitor, including gatekeeper mutant ALK","ALK;ROS1;IGF1R;EGFR;INSR;ABL1;FLT3;MET;ERBB2;ERBB4","Kinase inhibitor"]
["CC2D1A","AZD_5363",-0.384,0.058,0.701,2.47E-3,3.64,0.000269,0.000425,0.227,"0/+","AKT inhibitor","AKT1;AKT2;AKT3;ROCK2","Kinase inhibitor"]
["APLP2","Givinostat",-0.264,0.202,0.763,0.000586,3.64,0.000271,4.26E-4,0.227,"0/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC10","Differentiating.epigenetic modifier"]
["BLZF1","Dactolisib",-0.222,0.286,0.781,0.000354,3.64,0.000271,4.28E-4,0.227,"0/+","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;ATR;RPS6KB1","Kinase inhibitor"]
["AP2A1","Cytarabine",-0.642,0.000538,0.471,0.0654,3.64,2.72E-4,4.28E-4,0.227,"-/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["KCTD3","A_419259",0.37,0.0686,-0.759,0.000645,-3.95,{"v":7.69e-05,"d":"7.69E-05"},0.000182,0.227,"0/-","HCK and other SRC family kinase inhibitor","SRC;LCK;LYN;HCK","Kinase inhibitor"]
["MMS19","Mocetinostat",-0.588,2E-3,0.61,0.0122,3.95,{"v":7.73e-05,"d":"7.73E-05"},1.84E-4,0.227,"-/+","HDAC inhibitor (HDAC1 and 2-selective)","HDAC1;HDAC2;HDAC3;HDAC11","Differentiating.epigenetic modifier"]
["LSM1","Regorafenib",-0.247,0.235,0.811,1.37E-4,3.95,{"v":7.78e-05,"d":"7.78E-05"},1.84E-4,0.227,"0/+","BRAF, c-Kit, VEGFR2 inhibitor","BRAF;RAF1;KIT;KDR;FLT1;RET;PDGFRB;FLT4","Kinase inhibitor"]
["MAT2A","Prexasertib",0.774,{"v":5.53e-06,"d":"5.53E-06"},-0.337,0.202,-3.95,{"v":7.79e-05,"d":"7.79E-05"},1.84E-4,0.227,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["MTFR2","Prexasertib",0.876,{"v":9.26e-09,"d":"9.26E-09"},-0.133,0.623,-4.27,{"v":1.94e-05,"d":"1.94E-05"},{"v":6.65e-05,"d":"6.65E-05"},0.227,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["NPM1","GSK269962",0.445,0.0257,-0.767,5.22E-4,-4.27,{"v":1.99e-05,"d":"1.99E-05"},{"v":6.65e-05,"d":"6.65E-05"},0.227,"+/-","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["REL","Pemetrexed",-0.674,0.000221,0.598,0.0144,4.31,{"v":1.62e-05,"d":"1.62E-05"},{"v":5.48e-05,"d":"5.48E-05"},0.227,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["RELL1","Clofarabine",-0.388,0.0553,0.8,0.000198,4.31,{"v":1.62e-05,"d":"1.62E-05"},{"v":5.51e-05,"d":"5.51E-05"},0.227,"0/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["SNUPN","Toremifene",0.636,0.000631,-0.557,0.0249,-3.95,{"v":7.93e-05,"d":"7.93E-05"},1.75E-4,0.227,"+/-","Selective estrogen receptor modulator","ESR1;SHBG","Hormone therapy"]
["SKP1","Epirubicin",0.598,0.00159,-0.598,0.0144,-3.94,{"v":8e-05,"d":"8.00E-05"},1.76E-4,0.227,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["TMX1","Ridaforolimus",-0.436,0.0292,0.722,0.0016,3.94,{"v":8.09e-05,"d":"8.09E-05"},0.000178,0.227,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["TBC1D10C","Cytarabine.Idarubicin",-0.375,0.0645,0.755,0.000724,3.94,{"v":8.09e-05,"d":"8.09E-05"},0.000178,0.227,"0/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["SPG21","Vinorelbine",-0.518,0.00795,0.666,0.00483,3.94,{"v":8.17e-05,"d":"8.17E-05"},0.000178,0.227,"-/+","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["SYMPK","AMG319",-0.361,0.0765,0.761,0.000612,3.94,{"v":8.26e-05,"d":"8.26E-05"},0.000179,0.227,"0/+","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["TENT2","Panobinostat",-0.492,0.0125,0.685,0.00342,3.94,{"v":8.28e-05,"d":"8.28E-05"},0.00018,0.227,"-/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["TOM1L2","CC_223",-0.578,2.47E-3,0.615,0.0113,3.93,{"v":8.35e-05,"d":"8.35E-05"},0.000182,0.227,"-/+","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["TMEM245","AZD_5363",-0.548,0.00461,0.642,0.00737,3.93,{"v":8.38e-05,"d":"8.38E-05"},0.000182,0.227,"-/+","AKT inhibitor","AKT1;AKT2;AKT3;ROCK2","Kinase inhibitor"]
["SFXN5","Omaveloxolone",-0.249,0.23,0.808,0.000152,3.93,{"v":8.42E-5,"d":"8.42E-05"},1.83E-4,0.227,"0/+","Nrf2 activator","NFE2L2","Other"]
["SFPQ","GSK269962",0.524,0.00721,-0.66,0.00538,-3.93,{"v":8.52e-05,"d":"8.52E-05"},1.85E-4,0.227,"+/-","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["SNX22","Belinostat",0.566,0.00319,-0.625,0.00966,-3.93,{"v":8.53E-5,"d":"8.53E-05"},1.85E-4,0.227,"+/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["TMEM134","Cladribine",-0.646,0.000488,0.541,0.0303,3.93,{"v":8.54e-05,"d":"8.54E-05"},1.85E-4,0.227,"-/+","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["SH3BP2","TAK_901",-0.604,1.39E-3,0.588,0.0165,3.93,{"v":8.55e-05,"d":"8.55E-05"},0.000186,0.227,"-/+","Aurora, Src family, JAK3, RTK inhibitor","AURKA;AURKB;JAK3;SRC;CLK2;FGR;LRRK2;YES1;LCK;FYN;ABL1;AXL;ABL2;HCK;RET;FRK;NTRK1;FGFR2","Kinase inhibitor"]
["TBC1D31","Radotinib",0.719,{"v":5.08e-05,"d":"5.08E-05"},-0.436,0.0914,-3.93,{"v":8.64e-05,"d":"8.64E-05"},0.000187,0.227,"+/0","ABL, PDGFR inhibitor","ABL1;PDGFRA;PDGFRB","Kinase inhibitor"]
["SERPINC1","Hydroxyurea",-0.529,0.00659,0.656,0.00583,3.93,{"v":8.65e-05,"d":"8.65E-05"},0.000188,0.227,"-/+","Antineoplastic agent","RRM1","Conv.Chemo"]
["SPG11","VER_155008",-0.561,0.00352,0.628,0.00918,3.92,{"v":8.71e-05,"d":"8.71E-05"},0.000189,0.227,"-/+","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["TMED9","Prexasertib",-0.296,0.152,0.789,0.000282,3.92,{"v":8.72e-05,"d":"8.72E-05"},0.000189,0.227,"0/+","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["TARS2","Mocetinostat",-0.486,0.0138,0.687,3.29E-3,3.92,{"v":8.72e-05,"d":"8.72E-05"},0.000189,0.227,"-/+","HDAC inhibitor (HDAC1 and 2-selective)","HDAC1;HDAC2;HDAC3;HDAC11","Differentiating.epigenetic modifier"]
["TMA7","Perifosine",0.189,0.364,-0.828,{"v":7.61e-05,"d":"7.61E-05"},-3.92,{"v":8.77e-05,"d":"8.77E-05"},0.000189,0.227,"0/-","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["SLC12A2","IOX_1",0.419,0.037,-0.728,0.00138,-3.92,{"v":8.8e-05,"d":"8.80E-05"},0.00019,0.227,"+/-","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["TFB2M","Glasdegib",0.45,0.0239,-0.71,0.00208,-3.92,{"v":8.84e-05,"d":"8.84E-05"},0.00019,0.227,"+/-","Smo inhibitor","SMO","Hedgehog inhibitor"]
["SIKE1","Tipifarnib",0.314,0.127,-0.781,0.00036,-3.92,{"v":8.84e-05,"d":"8.84E-05"},0.00019,0.227,"0/-","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["SPRTN","Clofarabine",0.535,0.00585,-0.649,0.00652,-3.92,{"v":8.9e-05,"d":"8.90E-05"},0.000191,0.227,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["TDP2","SN_38",0.47,0.0178,-0.697,0.00271,-3.92,{"v":8.95e-05,"d":"8.95E-05"},1.92E-4,0.227,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["SERPINB6","AZD3965",-0.0491,0.816,0.867,{"v":1.38E-5,"d":"1.38E-05"},3.92,{"v":8.97e-05,"d":"8.97E-05"},1.93E-4,0.227,"0/+","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["SIGIRR","Clofarabine",-0.472,0.0172,0.695,2.82E-3,3.92,{"v":9.01e-05,"d":"9.01E-05"},1.93E-4,0.227,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["SKP1","Amsacrine",0.577,0.00252,-0.612,0.0118,-3.92,{"v":9.02e-05,"d":"9.02E-05"},1.93E-4,0.227,"+/-","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["CANX","Fimepinostat_CUDC_907",-0.45,0.0239,0.657,0.00567,3.64,0.000274,0.00043,0.228,"-/+","HDAC1, 2, 3, 10  and 11, PI3Kalpha inhibitor","HDAC1;HDAC2;HDAC3;HDAC10;HDAC11;PIK3CA","Differentiating.epigenetic modifier"]
["AC091230.1","Docetaxel",-0.441,0.0275,0.663,0.00509,3.64,0.000278,0.000431,0.228,"-/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["AIMP1","Prexasertib",0.627,7.94E-4,-0.489,0.0547,-3.63,0.00028,0.000432,0.228,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["LRR1","Amsacrine",0.492,0.0125,-0.686,3.31E-3,-3.94,{"v":8.01e-05,"d":"8.01E-05"},0.000186,0.228,"+/-","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["METTL2B","Raltitrexed",0.638,0.000597,-0.554,0.0259,-3.94,{"v":8.04e-05,"d":"8.04E-05"},0.000186,0.228,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["OSTM1","Temsirolimus",-0.507,0.00976,0.732,0.00126,4.26,{"v":2.02E-5,"d":"2.02E-05"},{"v":6.85e-05,"d":"6.85E-05"},0.228,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ORAI1","Raltitrexed",-0.544,0.00497,0.707,0.00219,4.26,{"v":2.03e-05,"d":"2.03E-05"},{"v":6.88e-05,"d":"6.88E-05"},0.228,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["PLEKHO2","Saracatinib",-0.361,0.076,0.805,0.00017,4.26,{"v":2.04e-05,"d":"2.04E-05"},{"v":6.88e-05,"d":"6.88E-05"},0.228,"0/+","Src, ABL inhibitor","ABL1;SRC;LCK;YES1;LYN;FYN;BLK;EGFR;KIT;EPHA2","Kinase inhibitor"]
["MTX1","Prexasertib",0.68,0.000182,-0.578,0.019,-4.26,{"v":2.07e-05,"d":"2.07E-05"},{"v":6.95e-05,"d":"6.95E-05"},0.229,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ATG9A","Everolimus",-0.427,0.0333,0.672,0.00433,3.63,0.00028,4.35E-4,0.23,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["FOXP1","Mitomycin_C",0.0172,0.935,-0.896,{"v":2.6e-06,"d":"2.60E-06"},-4.2,{"v":2.61e-05,"d":"2.61E-05"},{"v":8.7e-05,"d":"8.70E-05"},0.23,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["FER","Gemcitabine",-0.405,0.0448,0.779,0.00038,4.2,{"v":2.61e-05,"d":"2.61E-05"},{"v":8.7e-05,"d":"8.70E-05"},0.23,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["HASPIN","SN_38",0.572,2.8E-3,-0.674,0.00419,-4.2,{"v":2.68e-05,"d":"2.68E-05"},{"v":8.77e-05,"d":"8.77E-05"},0.23,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["FABP6","Doramapimod",-0.619,0.00097,0.632,0.00862,4.2,{"v":2.7e-05,"d":"2.70E-05"},{"v":8.82e-05,"d":"8.82E-05"},0.23,"-/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["ITPR3","Sunitinib",-0.756,{"v":1.26E-5,"d":"1.26E-05"},0.374,0.154,3.94,{"v":8.13e-05,"d":"8.13E-05"},0.000189,0.23,"-/0","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["MICAL1","A_1155463",0.475,0.0164,-0.697,0.00268,-3.94,{"v":8.14E-5,"d":"8.14E-05"},0.000189,0.23,"+/-","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2","Apoptotic modulator"]
["WDR90","BX_912",-0.33,0.108,0.786,0.000302,4.01,{"v":5.95e-05,"d":"5.95E-05"},0.000132,0.23,"0/+","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["TP53BP2","TAK_530",0.0888,0.673,-0.866,{"v":1.48e-05,"d":"1.48E-05"},-4.01,{"v":5.99e-05,"d":"5.99E-05"},0.000133,0.23,"0/-","Pan-HER inhibitor","EGFR;ERBB2;ERBB3","Kinase inhibitor"]
["YTHDF1","Megestrol_acetate",0.609,1.23E-3,-0.6,0.014,-4.01,{"v":6.19E-5,"d":"6.19E-05"},1.34E-4,0.23,"+/-","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["CARNMT1","Miltefosine",0.456,0.0221,-0.652,0.00617,-3.63,0.00028,0.000439,0.231,"+/-","Antimicrobial, inhibits PI3K and AKT","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Other"]
["CCDC85C","Vinblastine",0.24,0.248,-0.86,{"v":1.9e-05,"d":"1.90E-05"},-4.4,{"v":1.08E-5,"d":"1.08E-05"},{"v":5.13E-5,"d":"5.13E-05"},0.231,"0/-","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["LIAS","Pracinostat",-0.626,0.000823,0.567,0.0219,3.94,{"v":8.19e-05,"d":"8.19E-05"},0.000191,0.231,"-/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["KLHL12","Cladribine",0.521,0.00764,-0.664,0.00502,-3.94,{"v":8.25E-5,"d":"8.25E-05"},1.92E-4,0.231,"+/-","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["LLPH","GSK_1070916",0.262,0.206,-0.804,0.000177,-3.94,{"v":8.26e-05,"d":"8.26E-05"},1.92E-4,0.231,"0/-","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["LNPK","CC_115",-0.565,0.00328,0.628,0.00925,3.94,{"v":8.28e-05,"d":"8.28E-05"},1.93E-4,0.231,"-/+","mTOR, DNA-PK inhibitor","MTOR;PIK3CA;PRKDC","Kinase inhibitor"]
["RNF213","Cladribine",-0.387,0.0562,0.799,2.04E-4,4.3,{"v":1.71e-05,"d":"1.71E-05"},{"v":5.81e-05,"d":"5.81E-05"},0.231,"0/+","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["RNF5","SGC_CBP30",0.55,0.00444,-0.709,0.00212,-4.29,{"v":1.76e-05,"d":"1.76E-05"},{"v":5.93e-05,"d":"5.93E-05"},0.231,"+/-","CREBBP, EP300 bromodomain inhibitor","CREBBP","Differentiating.epigenetic modifier"]
["RABIF","PS_1145",-0.592,1.83E-3,0.676,0.00406,4.29,{"v":1.76e-05,"d":"1.76E-05"},{"v":5.93e-05,"d":"5.93E-05"},0.231,"-/+","IKK-2 inhibitor","IKBKB","Kinase inhibitor"]
["RELL1","Epirubicin",-0.418,0.0374,0.784,0.000325,4.29,{"v":1.77E-5,"d":"1.77E-05"},{"v":5.96e-05,"d":"5.96E-05"},0.231,"-/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["PPT1","Cytarabine",-0.361,0.0766,0.809,0.000149,4.29,{"v":1.78e-05,"d":"1.78E-05"},{"v":5.96e-05,"d":"5.96E-05"},0.231,"0/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["RMDN2","Entinostat",0.539,0.0054,-0.715,0.00185,-4.29,{"v":1.79e-05,"d":"1.79E-05"},{"v":5.98e-05,"d":"5.98E-05"},0.231,"+/-","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["ARHGAP1","Prexasertib",-0.678,0.000197,0.418,0.107,3.63,2.81E-4,0.000442,0.232,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ARHGAP42","Tucidinostat",0.607,0.00129,-0.513,0.0423,-3.63,2.81E-4,0.000442,0.232,"+/-","HDAC1, 2, 3 and 10 inhibitor","HDAC1;HDAC2;HDAC3;HDAC10","Differentiating.epigenetic modifier"]
["BCL7A","OTS167",0.507,0.00966,-0.612,0.0118,-3.63,2.81E-4,0.000442,0.232,"+/-","MELK inhibitor","MELK","Kinase inhibitor"]
["ACSM3","AMG319",-0.374,0.0657,0.705,2.31E-3,3.63,0.000286,4.44E-4,0.232,"0/+","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["CASP3","Axitinib",-0.633,0.000684,0.48,0.0601,3.63,0.000286,4.44E-4,0.232,"-/0","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["ANKIB1","Quizartinib",0.375,0.0644,-0.703,0.00236,-3.63,0.000287,0.000447,0.232,"0/-","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["AC004151.1","Cytarabine",-0.532,0.00618,0.589,0.0164,3.63,0.000287,0.00045,0.232,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["AHCYL2","GSK_461364",-0.56,3.62E-3,0.562,0.0234,3.63,0.000288,0.00045,0.232,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["ABI3","Etoposide",-0.557,3.79E-3,0.564,0.0228,3.63,0.000288,0.000451,0.232,"-/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["BMS1","Quizartinib",0.163,0.436,-0.802,0.000188,-3.63,0.000289,0.000451,0.232,"0/-","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["BCKDK","GSK_1070916",-0.43,0.032,0.669,0.00463,3.62,0.000289,0.000451,0.232,"-/+","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["AAMDC","BI_2536",-0.598,0.00159,0.521,0.0385,3.62,0.000289,0.000451,0.232,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["ABRAXAS1","Dasatinib",0.107,0.611,-0.821,{"v":9.59E-5,"d":"9.59E-05"},-3.62,0.000289,0.000452,0.232,"0/-","ABL, Src, Kit, EphR Inhibitor","ABL1","Kinase inhibitor"]
["ACAP2","A_1155463",0.553,0.00416,-0.568,0.0216,-3.62,0.000291,0.000452,0.232,"+/-","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2","Apoptotic modulator"]
["ACSF2","Niraparib",-0.349,0.0871,0.718,1.74E-3,3.62,0.000291,0.000452,0.232,"0/+","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["ATG9A","Sirolimus",-0.35,0.0859,0.717,0.00177,3.62,0.000291,0.000452,0.232,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["BIN1","AZD_5438",-0.354,0.0822,0.715,0.00186,3.62,2.92E-4,0.000454,0.232,"0/+","CDK1, 2, 9 inhibitor","CDK1;CDK2;CDK9","Kinase inhibitor"]
["CARD19","OSU_03012",-0.638,0.000601,0.472,0.065,3.62,2.92E-4,0.000454,0.232,"-/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["ATE1","TGR_1202",-0.606,1.31E-3,0.511,0.0433,3.62,0.000293,0.000454,0.232,"-/+","PI3Kdelta inhibitor","PIK3CD","Kinase inhibitor"]
["C10orf88","Fimepinostat_CUDC_907",0.454,0.0225,-0.65,0.00636,-3.62,0.000295,0.000456,0.232,"+/-","HDAC1, 2, 3, 10  and 11, PI3Kalpha inhibitor","HDAC1;HDAC2;HDAC3;HDAC10;HDAC11;PIK3CA","Differentiating.epigenetic modifier"]
["ACADM","OSU_03012",-0.726,{"v":4e-05,"d":"4.00E-05"},0.333,0.208,3.62,0.000295,0.000458,0.232,"-/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["ACP1","Daunorubicin",0.422,0.0355,-0.673,4.3E-3,-3.62,0.000296,0.000461,0.232,"+/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["ACSF2","Cytarabine.Idarubicin",-0.609,0.00122,0.506,0.0453,3.62,0.000296,0.000461,0.232,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["BUB1","Cabazitaxel",0.695,0.000114,-0.386,0.14,-3.62,0.000297,0.000462,0.232,"+/0","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["ATP6V0D1","Prexasertib",-0.702,{"v":9.11e-05,"d":"9.11E-05"},0.375,0.153,3.62,0.000297,0.000462,0.232,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ATAT1","PF_670462",0.463,0.0198,-0.644,0.00712,-3.62,0.000298,0.000463,0.232,"+/-","CK1epsilon and CK1delta inhibitor","CSNK1D;CSNK1E","Kinase inhibitor"]
["ANXA7","Ridaforolimus",-0.602,0.00145,0.514,0.0414,3.62,0.000298,0.000463,0.232,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["CAPN7","Fimepinostat_CUDC_907",-0.242,0.243,0.769,0.000497,3.62,0.000298,0.000465,0.232,"0/+","HDAC1, 2, 3, 10  and 11, PI3Kalpha inhibitor","HDAC1;HDAC2;HDAC3;HDAC10;HDAC11;PIK3CA","Differentiating.epigenetic modifier"]
["ADA2","Etoposide",-0.253,0.222,0.764,0.000567,3.62,0.000298,4.66E-4,0.232,"0/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["CAT","GSK_461364",-0.487,0.0135,0.625,0.00966,3.62,2.99E-4,0.000467,0.232,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["BSCL2","Trametinib",-0.559,3.65E-3,0.56,0.024,3.62,2.99E-4,0.000467,0.232,"-/+","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["ABRACL","AZD7762",-0.401,0.0468,0.686,0.00337,3.62,{"v":0.0003,"d":"3.00E-04"},0.000467,0.232,"-/+","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["C9orf78","Resminostat",0.329,0.108,-0.727,1.42E-3,-3.61,3.01E-4,0.000468,0.232,"0/-","HDAC1, 3, 6 inhibitor","HDAC1;HDAC3;HDAC6","Differentiating.epigenetic modifier"]
["AP3S1","Raltitrexed",-0.445,0.0259,0.656,0.00576,3.61,3.01E-4,0.000469,0.232,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["CBFB","Quisinostat",0.521,0.00753,-0.596,0.0149,-3.61,3.01E-4,0.000469,0.232,"+/-","HDAC inhibitor","HDAC1;HDAC2;HDAC4;HDAC10;HDAC11","Differentiating.epigenetic modifier"]
["ANXA7","Ribociclib",-0.501,0.0107,0.613,0.0116,3.61,0.000302,0.00047,0.232,"-/+","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["C1orf131","Dasatinib",0.305,0.139,-0.739,1.06E-3,-3.61,0.000302,0.00047,0.232,"0/-","ABL, Src, Kit, EphR Inhibitor","ABL1","Kinase inhibitor"]
["BLVRA","Fostamatinib",-0.46,0.0206,0.645,0.00701,3.61,0.000303,0.000471,0.232,"-/+","SYK inhibitor","SYK","Kinase inhibitor"]
["AC233755.2","Ravoxertinib",0.294,0.154,-0.745,0.000933,-3.61,0.000303,4.73E-4,0.232,"0/-","ERK inhibitor","MAPK3","Kinase inhibitor"]
["C1QBP","Dasatinib",0.156,0.457,-0.803,0.000181,-3.61,0.000303,0.000474,0.232,"0/-","ABL, Src, Kit, EphR Inhibitor","ABL1","Kinase inhibitor"]
["ATP2B4","Gemcitabine",-0.531,6.28E-3,0.586,0.017,3.61,0.000304,0.000474,0.232,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["AGO2","AT_406",0.652,0.000409,-0.449,0.0807,-3.61,0.000304,0.000474,0.232,"+/0","XIAP, cIAP1, cIAP2 inhibitor","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["C10orf88","ARV_825",0.566,0.0032,-0.553,0.0264,-3.61,0.000304,4.75E-4,0.232,"+/-","BET-targeting PROTAC","BRD4","Differentiating.epigenetic modifier"]
["AKR1A1","AT9283",-0.624,0.000851,0.486,0.0562,3.61,0.000305,4.75E-4,0.232,"-/0","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["CAPRIN1","Cytarabine.Idarubicin",0.666,0.000283,-0.43,0.0961,-3.61,0.000306,0.000476,0.232,"+/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["APBB1IP","Valrubicin",0.688,1.45E-4,-0.396,0.129,-3.61,0.000306,0.000476,0.232,"+/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["AMMECR1L","VER_155008",0.372,0.0674,-0.703,0.00241,-3.61,0.000307,0.000476,0.232,"0/-","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["AREL1","Cisplatin",-0.536,0.00573,0.581,0.0183,3.61,0.000308,0.000476,0.232,"-/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["ANXA5","Romidepsin",0.429,0.0323,-0.666,0.00485,-3.61,0.000308,0.000477,0.232,"+/-","HDAC inhibitor","HDAC1;HDAC2","Differentiating.epigenetic modifier"]
["ADGRE5","Saracatinib",-0.305,0.138,0.738,1.09E-3,3.61,0.000308,0.000478,0.232,"0/+","Src, ABL inhibitor","ABL1;SRC;LCK;YES1;LYN;FYN;BLK;EGFR;KIT;EPHA2","Kinase inhibitor"]
["ACSF2","Gemcitabine",-0.614,1.09E-3,0.498,0.0498,3.61,0.000309,0.000479,0.232,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["BCL11A","Bryostatin_1",-0.815,{"v":7.09e-07,"d":"7.09E-07"},0.12,0.657,3.61,0.000309,0.000479,0.232,"-/0","PKC activator","PRKCE;PRKCA;PRKCE;PRKD1;CASP8","Kinase inhibitor"]
["ADA2","Clofarabine",-0.212,0.308,0.78,0.00036,3.61,0.000309,0.00048,0.232,"0/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["ALYREF","Quizartinib",-0.547,0.00467,0.57,0.0211,3.61,0.000309,0.00048,0.232,"-/+","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["AC091230.1","Axitinib",-0.208,0.319,0.782,0.000342,3.61,0.000309,0.00048,0.232,"0/+","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["CARNMT1","Dovitinib",0.43,0.0319,-0.665,0.00493,-3.61,3.1E-4,0.00048,0.232,"+/-","FGFR inhibitor","FGFR1;FGFR3;KIT;FLT3;FLT4","Kinase inhibitor"]
["ABHD17C","AT_101",-0.379,0.0615,0.698,0.00267,3.61,3.1E-4,0.000482,0.232,"0/+","pan Bcl-2 family inhibitor","BCL2;BCL2L1;MCL1","Apoptotic modulator"]
["ATIC","Clofarabine",0.637,6.2E-4,-0.469,0.0669,-3.61,0.000311,0.000482,0.232,"+/0","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["ATL3","Sapanisertib",-0.52,0.00767,0.594,0.0152,3.61,0.000311,0.000482,0.232,"-/+","mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["AAR2","OTS167",0.149,0.477,-0.804,0.000172,-3.61,0.000312,0.000483,0.232,"0/-","MELK inhibitor","MELK","Kinase inhibitor"]
["ABCD3","Eltanexor",0.25,0.228,-0.764,0.000569,-3.61,0.000312,4.84E-4,0.232,"0/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["BAG6","CUDC_305",0.243,0.242,-0.767,0.000523,-3.61,0.000312,0.000485,0.232,"0/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["AKAP13","Midostaurin",-0.404,0.0452,0.682,3.62E-3,3.6,0.000312,0.000485,0.232,"-/+","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["ADGRE5","AZD1152_HQPA",-0.369,0.0693,0.703,0.00239,3.6,0.000314,4.86E-4,0.232,"0/+","Aurora B inhibitor","AURKB","Kinase inhibitor"]
["AASS","GSK_1070916",0.552,0.00426,-0.565,0.0227,-3.6,0.000315,4.86E-4,0.232,"+/-","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["ABRAXAS1","Canertinib",0.294,0.153,-0.743,0.000981,-3.6,0.000316,4.86E-4,0.232,"0/-","Pan-HER inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["AKIRIN1","Paclitaxel",0.466,0.0188,-0.638,0.00785,-3.6,0.000316,0.000488,0.232,"+/-","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["ARF6","Fludarabine",-0.41,0.0421,0.678,0.00392,3.6,0.000317,0.00049,0.232,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["ASXL1","Ridaforolimus",0.499,0.0111,-0.612,0.0118,-3.6,0.000317,0.000491,0.232,"+/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["BSPRY","Pexidartinib",-0.613,0.00112,0.497,0.0501,3.6,0.000318,0.000491,0.232,"-/0","KIT, CSF1R, FLT3 inhibitor","CSF1R;FLT3;KIT","Kinase inhibitor"]
["AKIRIN2","Paclitaxel",0.257,0.215,-0.76,0.000633,-3.6,0.000318,0.000492,0.232,"0/-","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["ALDH1A2","Tubastatin_A",0.145,0.488,-0.805,0.000168,-3.6,3.19E-4,0.000492,0.232,"0/-","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["ARL3","GSK_461364",-0.448,0.0248,0.651,6.3E-3,3.6,0.00032,0.000493,0.232,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["BRAT1","Onalespib",0.414,0.0397,-0.674,0.00418,-3.6,0.00032,0.000493,0.232,"+/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["C11orf68","Entinostat",-0.345,0.0908,0.715,0.00184,3.6,0.000322,0.000494,0.232,"0/+","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["CDC7","SN_38",0.494,0.012,-0.759,0.000649,-4.39,{"v":1.13E-5,"d":"1.13E-05"},{"v":5.36e-05,"d":"5.36E-05"},0.232,"+/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["CHORDC1","Prexasertib",0.763,{"v":9.35e-06,"d":"9.35E-06"},-0.486,0.0566,-4.38,{"v":1.18e-05,"d":"1.18E-05"},{"v":5.51e-05,"d":"5.51E-05"},0.232,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["CS","SB743921",-0.377,0.0633,0.812,0.000132,4.37,{"v":1.22E-5,"d":"1.22E-05"},{"v":5.56e-05,"d":"5.56E-05"},0.232,"0/+","Mitotic inhibitor, Eg5, KSP inhibitor","KIF11","Kinesin inhibitor"]
["DNAJC7","Raltitrexed",0.818,{"v":5.82E-7,"d":"5.82E-07"},-0.361,0.169,-4.37,{"v":1.22E-5,"d":"1.22E-05"},{"v":5.56e-05,"d":"5.56E-05"},0.232,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["CIZ1","SAR405838",0.527,0.00682,-0.737,0.00113,-4.37,{"v":1.23e-05,"d":"1.23E-05"},{"v":5.56e-05,"d":"5.56E-05"},0.232,"+/-","MDM2 inhibitor","MDM2;TP53","Apoptotic modulator"]
["CYTH1","ML390",-0.393,0.0521,0.805,1.66E-4,4.37,{"v":1.24E-5,"d":"1.24E-05"},{"v":5.56e-05,"d":"5.56E-05"},0.232,"0/+","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["POLL","VER_155008",-0.586,0.00207,0.679,0.00385,4.28,{"v":1.84E-5,"d":"1.84E-05"},{"v":6.18e-05,"d":"6.18E-05"},0.232,"-/+","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["SASS6","Selinexor",0.339,0.0971,-0.816,1.16E-4,-4.28,{"v":1.84E-5,"d":"1.84E-05"},{"v":6.18e-05,"d":"6.18E-05"},0.232,"0/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["RELL1","Daunorubicin",-0.397,0.0494,0.792,0.000253,4.28,{"v":1.86e-05,"d":"1.86E-05"},{"v":6.21e-05,"d":"6.21E-05"},0.232,"-/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["RAD54B","Dasatinib",0.109,0.605,-0.883,{"v":5.98e-06,"d":"5.98E-06"},-4.28,{"v":1.88E-5,"d":"1.88E-05"},{"v":6.28e-05,"d":"6.28E-05"},0.232,"0/-","ABL, Src, Kit, EphR Inhibitor","ABL1","Kinase inhibitor"]
["TNKS2","Cytarabine",0.553,0.00412,-0.631,0.0087,-3.91,{"v":9.32e-05,"d":"9.32E-05"},0.000198,0.232,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["TIGD2","Canertinib",0.239,0.25,-0.808,0.00015,-3.91,{"v":9.38e-05,"d":"9.38E-05"},0.000199,0.232,"0/-","Pan-HER inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["ADD2","AZD_6482",0.446,0.0254,-0.652,0.00624,-3.6,0.000323,4.95E-4,0.233,"+/-","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["CBFA2T3","AZD1208",0.658,0.000347,-0.436,0.091,-3.59,0.000324,0.000496,0.233,"+/0","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["AGO1","Cisplatin",-0.559,0.00369,0.556,0.0254,3.59,0.000324,0.000498,0.233,"-/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["LXN","UCN_01",-0.434,0.0303,0.722,0.0016,3.93,{"v":8.42E-5,"d":"8.42E-05"},1.95E-4,0.233,"-/+","PKCbeta, PDK1, Chk, Cdk2 inhibitor","PRKCB;PDPK1","Kinase inhibitor"]
["MROH1","Cytarabine",-0.518,0.00793,0.665,0.00497,3.93,{"v":8.45e-05,"d":"8.45E-05"},0.000196,0.233,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["KIF23","Cytarabine",0.629,0.000751,-0.561,0.0236,-3.93,{"v":8.46e-05,"d":"8.46E-05"},0.000196,0.233,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["KIAA0930","BAY_87_2243",-0.438,0.0285,0.718,1.73E-3,3.93,{"v":8.62e-05,"d":"8.62E-05"},{"v":0.0002,"d":"2.00E-04"},0.233,"-/+","HIF1alpha inhibitor","HIF1A","Differentiating.epigenetic modifier"]
["MRFAP1","GSK_461364",0.624,8.52E-4,-0.565,0.0225,-3.92,{"v":8.73e-05,"d":"8.73E-05"},0.000201,0.233,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["MND1","Pemetrexed",0.53,0.00642,-0.653,0.00606,-3.92,{"v":8.84e-05,"d":"8.84E-05"},2.03E-4,0.233,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["INPP5A","TGR_1202",-0.326,0.111,0.775,0.000422,3.92,{"v":8.84e-05,"d":"8.84E-05"},2.03E-4,0.233,"0/+","PI3Kdelta inhibitor","PIK3CD","Kinase inhibitor"]
["MICU1","Sirolimus",-0.355,0.0812,0.761,6.11E-4,3.92,{"v":8.86e-05,"d":"8.86E-05"},2.04E-4,0.233,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["LRR1","Clofarabine",0.434,0.0302,-0.719,0.00169,-3.92,{"v":8.9e-05,"d":"8.90E-05"},2.04E-4,0.233,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["LRRC1","Vorinostat",0.615,1.06E-3,-0.574,0.02,-3.92,{"v":8.9e-05,"d":"8.90E-05"},2.04E-4,0.233,"+/-","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["MRFAP1L1","Imiquimod",0.0422,0.841,0.888,{"v":4.38e-06,"d":"4.38E-06"},3.92,{"v":8.97e-05,"d":"8.97E-05"},0.000206,0.233,"0/+","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["MAVS","SN_38",-0.603,1.42E-3,0.586,0.017,3.92,{"v":8.98e-05,"d":"8.98E-05"},0.000206,0.233,"-/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["ICE1","Danusertib",0.291,0.159,-0.79,0.000274,-3.92,{"v":9e-05,"d":"9.00E-05"},0.000207,0.233,"0/-","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["MPV17","Tasquinimod",-0.841,{"v":1.36E-7,"d":"1.36E-07"},0.143,0.598,3.92,{"v":9e-05,"d":"9.00E-05"},0.000207,0.233,"-/0","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["IDE","Prexasertib",0.789,{"v":2.73e-06,"d":"2.73E-06"},-0.291,0.273,-3.92,{"v":9.01e-05,"d":"9.01E-05"},0.000207,0.233,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["MARCKSL1","AZD8055",0.564,3.3E-3,-0.623,0.00988,-3.91,{"v":9.04e-05,"d":"9.04E-05"},0.000207,0.233,"+/-","mTOR inhibitor","MTOR","Kinase inhibitor"]
["LEPROTL1","GSK2636771",-0.588,1.97E-3,0.601,0.0139,3.91,{"v":9.06e-05,"d":"9.06E-05"},0.000207,0.233,"-/+","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["LIAS","S_63845",-0.575,0.00262,0.613,0.0116,3.91,{"v":9.12e-05,"d":"9.12E-05"},0.000208,0.233,"-/+","MCL-1 inhibitor","MCL1","Apoptotic modulator"]
["IRS1","Pevonedistat",0.304,0.14,-0.784,0.000327,-3.91,{"v":9.13e-05,"d":"9.13E-05"},0.000208,0.233,"0/-","NAE inhibitor","NAE1","Metabolic modifier"]
["MFSD10","ODM_201",-0.633,0.000676,0.552,0.0266,3.91,{"v":9.14e-05,"d":"9.14E-05"},0.000208,0.233,"-/+","AR antagonist","AR","Hormone therapy"]
["MIS18A","Raltitrexed",0.585,0.00212,-0.603,0.0134,-3.91,{"v":9.16e-05,"d":"9.16E-05"},0.000208,0.233,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["MAP4K5","Canertinib",-0.564,3.32E-3,0.623,0.00997,3.91,{"v":9.18e-05,"d":"9.18E-05"},0.000208,0.233,"-/+","Pan-HER inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["L2HGDH","Saracatinib",-0.592,1.82E-3,0.596,0.0149,3.91,{"v":9.26e-05,"d":"9.26E-05"},0.00021,0.233,"-/+","Src, ABL inhibitor","ABL1;SRC;LCK;YES1;LYN;FYN;BLK;EGFR;KIT;EPHA2","Kinase inhibitor"]
["KIF4A","Raltitrexed",0.749,{"v":1.63E-5,"d":"1.63E-05"},-0.376,0.151,-3.91,{"v":9.31E-5,"d":"9.31E-05"},0.00021,0.233,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["MLLT11","GSK269962",0.395,0.0509,-0.74,1.06E-3,-3.91,{"v":9.33e-05,"d":"9.33E-05"},0.00021,0.233,"0/-","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["PPT1","Pemetrexed",-0.601,1.48E-3,0.664,0.00501,4.28,{"v":1.91E-5,"d":"1.91E-05"},{"v":6.38e-05,"d":"6.38E-05"},0.233,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["SPAG5","Gemcitabine",0.607,0.0013,-0.58,0.0185,-3.9,{"v":9.44e-05,"d":"9.44E-05"},0.000201,0.233,"+/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["TNKS","Palbociclib",0.756,{"v":1.25e-05,"d":"1.25E-05"},-0.362,0.168,-3.9,{"v":9.47e-05,"d":"9.47E-05"},0.000201,0.233,"+/0","Topoisomerase I inhibitor, Camptothecin analog","CDK4;CDK6","Kinase inhibitor"]
["TMEM9","OTS167",0.455,0.0223,-0.703,0.00236,-3.9,{"v":9.52e-05,"d":"9.52E-05"},2.02E-4,0.233,"+/-","MELK inhibitor","MELK","Kinase inhibitor"]
["TIMP1","CC_223",-0.468,0.0183,0.695,2.82E-3,3.9,{"v":9.57e-05,"d":"9.57E-05"},2.04E-4,0.233,"-/+","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["SLC25A25","Digoxin",-0.464,0.0196,0.698,2.66E-3,3.9,{"v":9.57e-05,"d":"9.57E-05"},2.04E-4,0.233,"-/+","Cardiac glycoside","ATP1A1;ITGB1;ITGB3;ITGA3;ITGA1","Other"]
["SSH3","Binimetinib",-0.104,0.62,0.851,{"v":2.93e-05,"d":"2.93E-05"},3.9,{"v":9.64e-05,"d":"9.64E-05"},2.04E-4,0.233,"0/+","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["BIRC5","Cytarabine.Idarubicin",0.623,0.000871,-0.483,0.058,-3.59,0.000325,{"v":0.0005,"d":"5.00E-04"},0.234,"+/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["C10orf88","Vorinostat",0.676,0.000206,-0.409,0.115,-3.59,0.000326,0.000503,0.234,"+/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["ARPC1B","Prexasertib",-0.646,0.000492,0.454,0.0775,3.59,0.000327,0.000503,0.234,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["CCDC102A","Daporinad",0.697,0.000109,-0.375,0.152,-3.59,0.000331,5.04E-4,0.234,"+/0","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["ARID3B","Tivozanib",-0.0942,0.654,0.821,{"v":9.55e-05,"d":"9.55E-05"},3.59,0.000331,5.04E-4,0.234,"0/+","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["CNP","GSK_461364",-0.596,0.00168,0.683,0.00353,4.35,{"v":1.37e-05,"d":"1.37E-05"},{"v":6.01e-05,"d":"6.01E-05"},0.234,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["CRELD2","Acitretin",-0.563,0.0034,0.708,0.00217,4.34,{"v":1.41e-05,"d":"1.41E-05"},{"v":6.08e-05,"d":"6.08E-05"},0.234,"-/+","Retinoic acid receptor agonist","RARA;RARB;RXRA;RXRB;RXRG","Differentiating.epigenetic modifier"]
["DDX60","Clofarabine",-0.486,0.0138,0.756,0.000703,4.34,{"v":1.44e-05,"d":"1.44E-05"},{"v":6.16e-05,"d":"6.16E-05"},0.234,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["CKAP2","Selinexor",0.528,0.00671,-0.73,1.31E-3,-4.34,{"v":1.46e-05,"d":"1.46E-05"},{"v":6.18e-05,"d":"6.18E-05"},0.234,"+/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["CUEDC2","Paclitaxel",0.587,0.00203,-0.687,0.00327,-4.33,{"v":1.46e-05,"d":"1.46E-05"},{"v":6.18e-05,"d":"6.18E-05"},0.234,"+/-","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["DCP1B","Miltefosine",0.372,0.0675,-0.81,1.45E-4,-4.33,{"v":1.47E-5,"d":"1.47E-05"},{"v":6.18e-05,"d":"6.18E-05"},0.234,"0/-","Antimicrobial, inhibits PI3K and AKT","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Other"]
["CTU2","WEHI_539",-0.492,0.0125,0.751,0.000792,4.33,{"v":1.49E-5,"d":"1.49E-05"},{"v":6.21e-05,"d":"6.21E-05"},0.234,"-/+","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["CIZ1","Alisertib",0.545,0.00484,-0.718,1.74E-3,-4.33,{"v":1.5E-5,"d":"1.50E-05"},{"v":6.25e-05,"d":"6.25E-05"},0.234,"+/-","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["CIZ1","Idasanutlin",0.499,0.0111,-0.746,0.000905,-4.32,{"v":1.54e-05,"d":"1.54E-05"},{"v":6.35e-05,"d":"6.35E-05"},0.234,"+/-","p53-MDM2 inhibitor","TP53;MDM2","Apoptotic modulator"]
["CS","AZD_8186",-0.309,0.133,0.831,{"v":6.69E-5,"d":"6.69E-05"},4.32,{"v":1.58e-05,"d":"1.58E-05"},{"v":6.48e-05,"d":"6.48E-05"},0.234,"0/+","PI3K beta inhibitor","PIK3CG","Kinase inhibitor"]
["DBF4","WEHI_539",-0.697,1.07E-4,0.569,0.0214,4.31,{"v":1.62e-05,"d":"1.62E-05"},{"v":6.55e-05,"d":"6.55E-05"},0.234,"-/+","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["CTBS","Cytarabine",-0.661,0.000325,0.614,0.0115,4.31,{"v":1.62e-05,"d":"1.62E-05"},{"v":6.55e-05,"d":"6.55E-05"},0.234,"-/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["CD83","AZD1208",0.405,0.0447,-0.793,0.000251,-4.31,{"v":1.63E-5,"d":"1.63E-05"},{"v":6.58E-5,"d":"6.58E-05"},0.234,"+/-","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["CDC25A","Flutamide",-0.21,0.315,0.86,{"v":1.91E-5,"d":"1.91E-05"},4.31,{"v":1.64e-05,"d":"1.64E-05"},{"v":6.58E-5,"d":"6.58E-05"},0.234,"0/+","Nonsteroidal antiandrogen","AR;AHR;NR1I2","Hormone therapy"]
["DNAJC11","BX_912",0.529,0.00653,-0.725,1.49E-3,-4.31,{"v":1.65e-05,"d":"1.65E-05"},{"v":6.6e-05,"d":"6.60E-05"},0.234,"+/-","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["DHX37","Quizartinib",0.6,0.00153,-0.672,0.00439,-4.31,{"v":1.66E-5,"d":"1.66E-05"},{"v":6.63e-05,"d":"6.63E-05"},0.234,"+/-","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["ILVBL","Alisertib",-0.452,0.0234,0.706,0.00223,3.91,{"v":9.39e-05,"d":"9.39E-05"},2.13E-4,0.234,"-/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["SH3BP2","Cytarabine.Idarubicin",-0.66,0.000334,0.516,0.0409,3.9,{"v":9.8e-05,"d":"9.80E-05"},0.000207,0.234,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["STARD10","Trametinib",0.0751,0.721,-0.858,{"v":2.09E-5,"d":"2.09E-05"},-3.89,{"v":9.82e-05,"d":"9.82E-05"},0.000207,0.234,"0/-","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["SLC27A1","Temsirolimus",-0.641,0.000552,0.539,0.0314,3.89,{"v":9.84e-05,"d":"9.84E-05"},0.000208,0.234,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SLC4A2","8_amino_adenosine",-0.537,0.00559,0.642,0.00733,3.89,{"v":9.87E-5,"d":"9.87E-05"},0.000208,0.234,"-/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["UBA7","Raltitrexed",-0.435,0.0296,0.732,0.00126,4,{"v":6.27e-05,"d":"6.27E-05"},1.37E-4,0.234,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["VAMP5","Losmapimod",-0.0902,0.668,-0.903,{"v":1.65e-06,"d":"1.65E-06"},-4,{"v":6.37e-05,"d":"6.37E-05"},0.000138,0.234,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["ZPR1","Ganetespib",0.476,0.0162,-0.706,0.00224,-3.99,{"v":6.54e-05,"d":"6.54E-05"},0.00014,0.234,"+/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["VPS29","Prexasertib",-0.744,{"v":1.99e-05,"d":"1.99E-05"},0.41,0.115,3.99,{"v":6.64e-05,"d":"6.64E-05"},0.000142,0.234,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["TRAPPC10","Alisertib",-0.678,1.95E-4,0.515,0.0413,3.99,{"v":6.66e-05,"d":"6.66E-05"},1.44E-4,0.234,"-/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["UNK","Filanesib",-0.38,0.0608,0.759,0.000644,3.99,{"v":6.67e-05,"d":"6.67E-05"},1.44E-4,0.234,"0/+","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["UBR5","Ridaforolimus",0.48,0.0152,-0.703,0.0024,-3.99,{"v":6.67e-05,"d":"6.67E-05"},1.44E-4,0.234,"+/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["WDR47","Vandetanib",-0.448,0.0245,0.722,0.00159,3.99,{"v":6.69E-5,"d":"6.69E-05"},1.44E-4,0.234,"-/+","VEGFR, EGFR, RET inhibitor","KDR;FLT4;EGFR;RET","Kinase inhibitor"]
["VAMP5","Floxuridine",-0.609,1.24E-3,0.596,0.0147,3.99,{"v":6.7e-05,"d":"6.70E-05"},1.44E-4,0.234,"-/+","Antimetabolite, Analog of 5-fluorouracil","TYMS","Conv.Chemo"]
["TSR1","IOX_1",0.407,0.0432,-0.745,0.000924,-3.99,{"v":6.71e-05,"d":"6.71E-05"},1.44E-4,0.234,"+/-","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["YTHDF2","8_amino_adenosine",0.247,0.235,-0.815,0.000119,-3.99,{"v":6.73e-05,"d":"6.73E-05"},1.45E-4,0.234,"0/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["USP16","Cytarabine",0.416,0.0385,-0.74,0.00104,-3.98,{"v":6.76e-05,"d":"6.76E-05"},1.45E-4,0.234,"+/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["UBASH3A","Cisplatin",-0.333,0.104,0.781,0.000358,3.98,{"v":6.83e-05,"d":"6.83E-05"},1.45E-4,0.234,"0/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["YTHDF2","BX_912",0.34,0.0968,-0.777,0.000393,-3.98,{"v":6.88e-05,"d":"6.88E-05"},1.46E-4,0.234,"0/-","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["ZNF593","Pemetrexed",0.642,0.000542,-0.559,0.0245,-3.98,{"v":6.9e-05,"d":"6.90E-05"},1.46E-4,0.234,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["SKP1","Decitabine",0.319,0.12,-0.769,0.000498,-3.86,1.16E-4,0.000239,0.239,"0/-","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["SLC8A1","Paclitaxel",0.17,0.416,-0.818,0.000109,-3.78,0.000158,0.000304,0.24,"0/-","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["AKAP12","IOX_2",0.458,0.0214,-0.635,0.00825,-3.56,0.000378,0.000576,0.243,"+/-","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["ME2","Bleomycin",-0.74,{"v":2.33e-05,"d":"2.33E-05"},0.385,0.141,3.88,1.05E-4,2.32E-4,0.245,"-/0","Glycopeptide antibiotic, causes DNA breaks","DNA","Conv.Chemo"]
["NCAPH","Prexasertib",0.774,{"v":5.52e-06,"d":"5.52E-06"},-0.386,0.14,-4.11,{"v":3.93E-5,"d":"3.93E-05"},1.12E-4,0.247,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["DCAF12","Raltitrexed",0.771,{"v":6.46E-6,"d":"6.46E-06"},-0.411,0.114,-4.17,{"v":3.02e-05,"d":"3.02E-05"},1.06E-4,0.251,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["DGKE","Glesatinib",0.537,0.00565,-0.671,4.47E-3,-4.04,{"v":5.45e-05,"d":"5.45E-05"},1.56E-4,0.251,"+/-","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["AC093323.1","TAK_901",0.266,0.199,-0.738,1.09E-3,-3.48,0.000494,7.27E-4,0.255,"0/-","Aurora, Src family, JAK3, RTK inhibitor","AURKA;AURKB;JAK3;SRC;CLK2;FGR;LRRK2;YES1;LCK;FYN;ABL1;AXL;ABL2;HCK;RET;FRK;NTRK1;FGFR2","Kinase inhibitor"]
["TMEM268","Rocilinostat",0.481,0.0149,-0.633,0.00848,-3.63,0.00028,0.000465,0.256,"+/-","HDAC6 selective inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["XPR1","Clofarabine",0.569,0.00302,-0.601,0.0138,-3.83,0.000128,0.000247,0.262,"+/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["ODC1","Pracinostat",0.506,0.00991,-0.692,2.98E-3,-4.03,{"v":5.66E-5,"d":"5.66E-05"},0.000153,0.266,"+/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["UBE2F","Omaveloxolone",-0.458,0.0212,0.682,0.00361,3.8,1.47E-4,0.000277,0.268,"-/+","Nrf2 activator","NFE2L2","Other"]
["LTO1","Ibrutinib",0.18,0.39,-0.816,1.17E-4,-3.79,0.00015,0.000314,0.269,"0/-","BTK inhibitor","BTK;BLK;EGFR;FYN;LYN;LCK;BRAF;WNK1","Kinase inhibitor"]
["ADA2","Amsacrine",-0.211,0.31,0.747,0.000894,3.37,0.000746,0.00104,0.27,"0/+","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["ITIH2","Mercaptopurine",-0.521,0.00755,0.631,8.77E-3,3.78,0.000159,0.000332,0.272,"-/+","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["MBOAT7","Gemcitabine",-0.68,1.83E-4,0.452,0.0789,3.76,0.000167,0.000345,0.272,"-/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["MSRB2","AZD6738",-0.502,0.0106,0.664,0.005,3.87,1.11E-4,0.000259,0.274,"-/+","ATR inihibitor","ATR","Kinase inhibitor"]
["FAN1","BI_2536",-0.309,0.133,0.79,0.000275,3.97,{"v":7.1e-05,"d":"7.10E-05"},0.000178,0.277,"0/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["DCAF15","OTS167",0.217,0.298,-0.812,0.000132,-3.87,0.000109,0.000259,0.28,"0/-","MELK inhibitor","MELK","Kinase inhibitor"]
["ATP5MD","Docetaxel",-0.368,0.0705,0.65,0.00638,3.32,0.000898,0.00122,0.281,"0/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["CAPZB","BMS_911543",-0.226,0.278,0.729,0.00137,3.3,0.000954,0.00129,0.283,"0/+","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["FUBP1","Quizartinib",-0.71,{"v":6.99e-05,"d":"6.99E-05"},0.448,0.0818,3.92,{"v":9.02e-05,"d":"9.02E-05"},0.00021,0.283,"-/0","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["CMC4","Vorinostat",-0.656,0.000367,0.495,0.0515,3.8,1.46E-4,0.000334,0.285,"-/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["DPYSL4","Milciclib",-0.444,0.0262,0.674,0.0042,3.7,2.14E-4,0.00045,0.286,"-/+","CDK2 inhibitor","CDK2;CDK4;CDK5;CDK7;NTRK1","Kinase inhibitor"]
["ACP1","Idarubicin",0.24,0.248,-0.717,0.00178,-3.28,1.06E-3,1.4E-3,0.287,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["QDPR","BI_2536",-0.415,0.0392,0.731,0.00128,3.93,{"v":8.64e-05,"d":"8.64E-05"},2.04E-4,0.287,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["ARHGEF40","SB743921",-0.229,0.271,0.719,0.00169,3.26,0.00113,1.49E-3,0.288,"0/+","Mitotic inhibitor, Eg5, KSP inhibitor","KIF11","Kinesin inhibitor"]
["ACSS2","BMS863233",-0.617,0.00102,0.395,0.13,3.25,1.15E-3,0.00152,0.288,"-/0","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["ODC1","Tucidinostat",0.561,0.00354,-0.603,0.0135,-3.81,0.000141,0.000314,0.288,"+/-","HDAC1, 2, 3 and 10 inhibitor","HDAC1;HDAC2;HDAC3;HDAC10","Differentiating.epigenetic modifier"]
["SPATA2","Daporinad",-0.489,0.0132,0.585,0.0173,3.44,0.000575,0.000863,0.289,"-/+","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["TMEM131L","Doxorubicin",0.618,0.000983,-0.446,0.0834,-3.44,0.00059,8.83E-4,0.289,"+/0","Topoisomerase II inhibitor","TOP2A;NOLC1","Conv.Chemo"]
["GRN","Pemetrexed",-0.616,0.00104,0.536,0.0323,3.77,1.65E-4,3.39E-4,0.292,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["AMFR","Lonafarnib",0.415,0.0393,-0.589,0.0163,-3.2,1.4E-3,0.00179,0.295,"+/-","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["MFHAS1","Topotecan",-0.515,0.00841,0.607,0.0127,3.64,2.72E-4,5.04E-4,0.295,"-/+","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["KIAA1217","GSK269962",0.429,0.0325,-0.657,0.00573,-3.56,0.000372,0.000648,0.295,"+/-","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["APBB1IP","AT_101",-0.213,0.308,0.715,0.00186,3.18,1.47E-3,0.00187,0.296,"0/+","pan Bcl-2 family inhibitor","BCL2;BCL2L1;MCL1","Apoptotic modulator"]
["SLC15A4","Pracinostat",0.573,0.00274,-0.493,0.0522,-3.41,0.00065,0.000963,0.296,"+/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["PFDN4","GSK_1070916",0.406,0.0438,-0.709,0.00213,-3.76,0.00017,0.000364,0.298,"+/-","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["CAT","A_1331852",0.649,0.000451,-0.323,0.223,-3.17,0.00154,0.00195,0.299,"+/0","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2;MCL1","Apoptotic modulator"]
["CNOT7","Everolimus",0.0205,0.922,-0.848,{"v":3.32e-05,"d":"3.32E-05"},-3.63,0.000284,0.00056,0.299,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ACO2","OSU_03012",-0.668,0.000264,0.285,0.284,3.15,1.66E-3,0.00207,0.3,"-/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["RAB5C","Rigosertib",-0.71,{"v":6.97E-5,"d":"6.97E-05"},0.411,0.114,3.78,1.54E-4,0.000322,0.3,"-/0","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["PPP1R12B","AT_101",-0.301,0.144,0.762,0.000603,3.75,0.000179,3.59E-4,0.3,"0/+","pan Bcl-2 family inhibitor","BCL2;BCL2L1;MCL1","Apoptotic modulator"]
["C9orf64","Danusertib",0.12,0.567,-0.748,0.000854,-3.12,1.83E-3,0.00226,0.302,"0/-","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["METTL7A","VER_155008",-0.607,0.0013,0.481,0.0592,3.51,0.000447,7.45E-4,0.304,"-/0","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["DNAJC6","8_amino_adenosine",0.134,0.522,-0.811,0.000138,-3.62,2.99E-4,0.000587,0.305,"0/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["TECPR1","Galiellalactone",-0.324,0.114,0.678,0.00389,3.32,0.000896,0.00127,0.305,"0/+","STAT3-DNA interaction inhibitor","STAT3","Other"]
["TRIP6","Ipatasertib",0.401,0.0471,-0.694,0.00284,-3.66,0.00025,0.000438,0.305,"+/-","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["ZKSCAN2","Doramapimod",0.806,{"v":1.17E-6,"d":"1.17E-06"},-0.15,0.58,-3.62,0.000296,0.000512,0.305,"+/0","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["XRCC4","Megestrol_acetate",-0.435,0.0298,0.649,0.00654,3.54,0.000396,0.000642,0.305,"-/+","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["TBC1D13","Omipalisib",-0.429,0.0322,0.6,0.0141,3.29,0.000993,1.39E-3,0.307,"-/+","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["SUMO1","Vismodegib",-0.457,0.0216,0.575,0.0198,3.28,0.00102,0.00143,0.307,"-/+","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["FHOD1","Quizartinib",0.691,0.000129,-0.413,0.112,-3.69,0.000227,0.000447,0.308,"+/0","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["TCF7","Vismodegib",0.472,0.0173,-0.56,0.024,-3.27,1.06E-3,1.48E-3,0.309,"+/-","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["SGPL1","AZD1208",-0.492,0.0125,0.54,0.0308,3.27,1.09E-3,0.00151,0.311,"-/+","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["ACTR6","Prexasertib",0.454,0.0228,-0.525,0.0367,-3.07,2.16E-3,0.00262,0.313,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["SKP2","AZD1775",0.591,0.00187,-0.43,0.0961,-3.26,0.00113,0.00155,0.314,"+/0","Wee1 inhibitor","WEE1","Kinase inhibitor"]
["TCEAL8","PF_06463922",0.0572,0.786,-0.793,0.000251,-3.25,1.17E-3,0.0016,0.315,"0/-","ALK, ROS1 inhibitor","ALK;LTK;FER;FES;PTK2B;TNK2;PTK2;NTRK1;NTRK2;NTRK3;FRK;ROS1","Kinase inhibitor"]
["UAP1L1","Alisertib",-0.429,0.0325,0.639,0.00766,3.47,0.000512,0.00079,0.315,"-/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["AASDH","TH588",0.514,0.00853,-0.46,0.0734,-3.05,2.33E-3,0.00278,0.316,"+/0","MTH1 inhibitor","NUDT1","Metabolic modifier"]
["SREBF2","Volasertib",0.453,0.023,-0.565,0.0225,-3.23,1.25E-3,0.0017,0.316,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["TMEM135","Enzalutamide",0.251,0.225,-0.7,0.00256,-3.21,1.32E-3,0.00178,0.316,"0/-","AR antagonist","AR","Hormone therapy"]
["TIPIN","Deferoxamine",0.446,0.0253,-0.562,0.0236,-3.19,0.00143,1.9E-3,0.316,"+/-","Iron chelator","APP","Other"]
["LAT2","CC_223",-0.207,0.321,0.761,0.000625,3.45,0.000559,0.00089,0.317,"0/+","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["AP3S1","UCN_01",-0.572,2.81E-3,0.389,0.136,3.03,0.00241,0.00286,0.318,"-/0","PKCbeta, PDK1, Chk, Cdk2 inhibitor","PRKCB;PDPK1","Kinase inhibitor"]
["ATAD3B","Floxuridine",0.487,0.0135,-0.483,0.0583,-3.03,2.47E-3,0.00293,0.319,"+/0","Antimetabolite, Analog of 5-fluorouracil","TYMS","Conv.Chemo"]
["EIF3G","BMS863233",0.34,0.0966,-0.72,1.65E-3,-3.61,3.1E-4,0.000586,0.319,"0/-","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["C11orf98","Volasertib",0.606,1.32E-3,-0.34,0.198,-3.02,0.00252,2.99E-3,0.32,"+/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["MTFP1","Silmitasertib",-0.547,0.00466,0.551,0.0269,3.53,0.00042,0.000755,0.32,"-/+","CSNK2A1 inhibitor","CSNK2A1","Kinase inhibitor"]
["MARCKSL1","Ipatasertib",0.35,0.0864,-0.684,3.48E-3,-3.44,0.000592,0.000934,0.321,"0/-","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["RCOR1","Tazemetostat",-0.244,0.241,0.774,0.00043,3.66,0.000255,4.84E-4,0.321,"0/+","EZH2 inhibitor","EZH2","Differentiating.epigenetic modifier"]
["BYSL","PF_670462",0.415,0.039,-0.545,0.029,-3.01,0.0026,0.00307,0.322,"+/-","CK1epsilon and CK1delta inhibitor","CSNK1D;CSNK1E","Kinase inhibitor"]
["AAAS","GSK_461364",0.502,0.0105,-0.46,0.0727,-3,0.00268,3.16E-3,0.324,"+/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["TADA2B","CUDC_305",-0.504,0.0102,0.495,0.0511,3.14,0.0017,0.0022,0.324,"-/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["ERCC6","Cytarabine.Idarubicin",-0.501,0.0108,0.601,0.0138,3.56,0.000371,0.000675,0.325,"-/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["SSX2IP","8_amino_adenosine",0.257,0.216,-0.682,0.00359,-3.13,1.73E-3,0.00224,0.325,"0/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["ERP44","LY3023414",-0.459,0.0211,0.633,0.0085,3.55,0.000385,0.000697,0.326,"-/+","PI3K, mTOR, DNA-PK inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;PRKDC","Kinase inhibitor"]
["ATF2","BMS_911543",-0.326,0.112,0.608,0.0124,2.99,0.00284,3.32E-3,0.327,"0/+","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["C12orf10","ABT_751",0.64,0.000566,-0.277,0.3,-2.98,0.00288,0.00337,0.328,"+/0","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["EPC2","GSK269962",0.494,0.012,-0.596,0.0149,-3.51,0.000447,0.000788,0.329,"+/-","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["SCPEP1","Tucidinostat",0.124,0.555,-0.815,1.22E-4,-3.62,2.99E-4,0.000554,0.329,"0/-","HDAC1, 2, 3 and 10 inhibitor","HDAC1;HDAC2;HDAC3;HDAC10","Differentiating.epigenetic modifier"]
["INTS8","LY_2874455",0.464,0.0195,-0.593,0.0156,-3.38,0.000712,1.08E-3,0.33,"+/-","FGFR inhibitor","FGFR1;FGFR2;FGFR3","Kinase inhibitor"]
["AC118549.1","THZ2",0.28,0.175,-0.634,0.00833,-2.96,0.00305,0.00352,0.331,"0/-","CDK7 inhibitor","CDK7","Kinase inhibitor"]
["TET1","Givinostat",-0.312,0.129,0.641,0.00749,3.09,1.98E-3,0.00252,0.332,"0/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC10","Differentiating.epigenetic modifier"]
["HSPH1","Tamatinib",0.686,1.55E-4,-0.353,0.18,-3.45,5.53E-4,0.000936,0.333,"+/0","SYK inhibitor","SYK","Kinase inhibitor"]
["ICAM1","Tubacin",-0.234,0.26,0.733,1.23E-3,3.36,0.000789,0.00119,0.333,"0/+","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["TXNRD2","Fludarabine",-0.345,0.0912,0.671,0.00443,3.35,8.03E-4,1.15E-3,0.333,"0/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["ZNF274","Tipifarnib",-0.0744,0.724,0.797,0.000217,3.33,0.000865,0.00122,0.334,"0/+","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["BARD1","Tubacin",0.531,0.00634,-0.414,0.111,-2.95,0.00319,0.00368,0.335,"+/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["HPCAL1","Gemcitabine",-0.525,0.00699,0.544,0.0292,3.41,0.00064,0.00105,0.335,"-/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["GINS3","PF_03758309",0.375,0.0651,-0.657,0.00569,-3.38,0.000733,1.17E-3,0.335,"0/-","PAK4 inhibitor","PAK4","Kinase inhibitor"]
["TEP1","Tozasertib",-0.323,0.116,0.628,0.00918,3.07,2.16E-3,0.00272,0.335,"0/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["EIF1AX","S_63845",-0.256,0.217,0.725,1.48E-3,3.37,0.000744,0.00118,0.336,"0/+","MCL-1 inhibitor","MCL1","Apoptotic modulator"]
["IREB2","Methotrexate",0.629,0.000749,-0.4,0.125,-3.33,0.000873,0.0013,0.336,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["ANXA7","8_amino_adenosine",-0.359,0.0778,0.572,0.0206,2.93,0.00334,0.00384,0.337,"0/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["ADAM10","Uprosertib",-0.275,0.183,0.63,0.00888,2.93,0.00342,0.00393,0.338,"0/+","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["FBXL20","Clofarabine",-0.418,0.0375,0.621,0.0102,3.35,0.000806,0.00127,0.338,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["TRUB1","Fulvestrant",0.179,0.393,-0.75,0.000815,-3.3,0.000971,1.34E-3,0.338,"0/-","Estrogen receptor antagonist","ESR1","Hormone therapy"]
["YTHDF3","AZD1775",0.604,0.00138,-0.422,0.104,-3.29,1.01E-3,0.00138,0.339,"+/0","Wee1 inhibitor","WEE1","Kinase inhibitor"]
["EEF1A2","Floxuridine",0.418,0.0375,-0.634,0.00832,-3.41,0.000642,1.08E-3,0.34,"+/-","Antimetabolite, Analog of 5-fluorouracil","TYMS","Conv.Chemo"]
["TP53I3","Sunitinib",-0.33,0.107,0.663,5.11E-3,3.26,0.0011,1.48E-3,0.34,"0/+","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["ZBTB12","MK_2206",0.496,0.0117,-0.531,0.0343,-3.25,1.17E-3,0.00155,0.34,"+/-","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["CUL2","Pracinostat",-0.635,0.000658,0.416,0.109,3.41,0.000659,0.0011,0.341,"-/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["SERPINB9","Daporinad",-0.624,0.000856,0.321,0.226,3.04,0.00235,0.00292,0.341,"-/0","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["ERCC8","RGFP966",0.347,0.0895,-0.662,0.00523,-3.31,0.000934,0.00143,0.342,"0/-","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["HPCAL1","Oxaliplatin",-0.386,0.0569,0.63,0.00895,3.28,0.00104,1.56E-3,0.342,"0/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["STAP1","GSK923295",-0.27,0.192,0.655,0.00588,3.03,0.00243,0.00301,0.342,"0/+","CENP-E inhibitor","CENPE","Kinesin inhibitor"]
["HNRNPH1","GSK923295",0.398,0.0486,-0.615,0.0111,-3.26,0.00113,1.67E-3,0.343,"+/-","CENP-E inhibitor","CENPE","Kinesin inhibitor"]
["ATP1B3","OTS167",-0.578,0.0025,0.34,0.198,2.9,3.79E-3,0.00429,0.344,"-/0","MELK inhibitor","MELK","Kinase inhibitor"]
["OIP5","Cladribine",0.422,0.0354,-0.621,0.0102,-3.37,0.000762,1.23E-3,0.344,"+/-","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["AP3S1","Cisplatin",-0.391,0.0533,0.536,0.0324,2.89,0.00385,0.00436,0.345,"0/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["CDC45","Gemcitabine",0.319,0.12,-0.691,0.00302,-3.38,0.000738,0.00121,0.345,"0/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["ZNF593","RGFP966",0.559,3.65E-3,-0.459,0.0739,-3.22,0.00127,1.66E-3,0.345,"+/0","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["NT5C3B","ODM_201",0.391,0.0534,-0.642,0.00736,-3.36,0.000791,0.00127,0.346,"0/-","AR antagonist","AR","Hormone therapy"]
["BCCIP","Gemcitabine",0.361,0.0764,-0.558,0.0246,-2.88,3.96E-3,4.47E-3,0.347,"0/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["KBTBD7","Tacrolimus",0.118,0.575,-0.775,0.000427,-3.29,1.01E-3,1.47E-3,0.347,"0/-","binds FKBP12, causes inhibition of calcineurin","FKBP1A","Rapalog"]
["ABCC10","AZD1775",-0.514,0.00863,0.411,0.114,2.87,0.0041,4.62E-3,0.348,"-/0","Wee1 inhibitor","WEE1","Kinase inhibitor"]
["EIF3A","Cytarabine",0.317,0.123,-0.663,0.00508,-3.22,0.00128,0.00185,0.348,"0/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["TXNDC9","Idarubicin",0.387,0.056,-0.615,0.0112,-3.22,0.0013,0.0017,0.348,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["PROM1","Sorafenib",0.779,{"v":4.51E-6,"d":"4.51E-06"},-0.193,0.474,-3.54,0.000402,0.000714,0.349,"+/0","BRAF, FGFR-1, VEGFR-2 and -3, PDGFR-beta, KIT, and FLT3 inhibitor","BRAF;FGFR1;KDR;FLT3;KIT;FLT4;PDGFRB","Kinase inhibitor"]
["TRAF5","Venetoclax",0.125,0.552,-0.76,0.000633,-3.21,1.34E-3,1.75E-3,0.349,"0/-","Bcl-2 selective inhibitor","BCL2","Apoptotic modulator"]
["USP1","Perifosine",-0.13,0.534,0.757,0.000682,3.2,0.00136,0.00177,0.35,"0/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["MBP","Pomalidomide",-0.526,6.96E-3,0.509,0.0441,3.27,1.06E-3,0.00153,0.351,"-/+","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["TMEM161A","S_63845",-0.518,0.00804,0.439,0.0892,2.98,0.00285,3.48E-3,0.351,"-/0","MCL-1 inhibitor","MCL1","Apoptotic modulator"]
["ZCCHC7","Enzalutamide",0.182,0.384,-0.732,0.00127,-3.19,1.41E-3,0.00184,0.352,"0/-","AR antagonist","AR","Hormone therapy"]
["ANKRD46","Cabozantinib",0.292,0.157,-0.603,0.0135,-2.85,0.00433,0.00486,0.353,"0/-","VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor","KDR;MET;FLT3;KIT;RET;TEK","Kinase inhibitor"]
["BCKDK","Sirolimus",-0.37,0.0689,0.542,0.0302,2.84,0.00446,0.00498,0.353,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["TMEM259","Vismodegib",-0.0472,0.823,-0.797,0.000221,-2.98,0.00289,0.00352,0.353,"0/-","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["EVI5","Dovitinib",0.486,0.0139,-0.526,0.0365,-3.19,0.00144,0.00206,0.354,"+/-","FGFR inhibitor","FGFR1;FGFR3;KIT;FLT3;FLT4","Kinase inhibitor"]
["TIMM44","Cisplatin",0.392,0.0526,-0.554,0.0261,-2.97,0.00301,0.00366,0.354,"0/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["STAT4","C646",-0.428,0.0327,0.522,0.0382,2.96,0.00305,0.00369,0.355,"-/+","EP300, CREB-binding protein (CBP) inhibitor","EP300","Differentiating.epigenetic modifier"]
["ZNRF1","Verdinexor",-0.455,0.0223,0.55,0.0274,3.17,0.00153,0.00196,0.355,"-/+","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["COPA","Simvastatin",-0.834,{"v":2.28E-7,"d":"2.28E-07"},-0.0439,0.872,3.3,0.000952,1.5E-3,0.356,"-/0","HMG CoA reductase inhibitor","HMGCR","Metabolic modifier"]
["DNAJC30","Cladribine",0.598,0.00159,-0.425,0.101,-3.27,1.07E-3,1.65E-3,0.356,"+/0","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["SGTA","Raltitrexed",0.387,0.0558,-0.554,0.0259,-2.95,3.14E-3,3.79E-3,0.356,"0/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["CABLES1","Navitoclax",0.317,0.123,-0.578,0.019,-2.82,0.00475,0.00529,0.357,"0/-","Bcl-2,Bcl-XL inhibitor","BCL2;BCL2L2;BAD;BCL2L1;MCL1","Apoptotic modulator"]
["GUSB","Sirolimus",-0.529,0.00649,0.478,0.0612,3.17,0.00151,2.15E-3,0.357,"-/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["C19orf44","BX_912",-0.412,0.0406,0.498,0.0496,2.82,0.00486,0.0054,0.358,"-/+","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["F5","Hydroxyurea",-0.569,2.97E-3,0.43,0.0961,3.16,0.00155,0.0022,0.358,"-/0","Antineoplastic agent","RRM1","Conv.Chemo"]
["TTPAL","Cerdulatinib",0.407,0.0432,-0.587,0.0168,-3.16,1.57E-3,0.00202,0.358,"+/-","JAK, SYK inhibitor","JAK1;JAK2;JAK3;TYK2;SYK","Kinase inhibitor"]
["AP3M2","Amsacrine",-0.265,0.201,0.613,0.0117,2.81,0.00492,0.00546,0.359,"0/+","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["NAV1","Tamatinib",-0.295,0.152,0.687,3.3E-3,3.28,1.06E-3,0.00161,0.359,"0/+","SYK inhibitor","SYK","Kinase inhibitor"]
["CSK","Vincristine",-0.39,0.0537,0.618,0.0107,3.24,0.00118,0.00179,0.36,"0/+","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB;TUBA4A","Conv.Chemo"]
["SIT1","Entinostat",0.658,3.5E-4,-0.232,0.388,-2.93,0.00338,0.00405,0.36,"+/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["AASDHPPT","Temsirolimus",0.141,0.502,-0.684,0.00345,-2.8,0.00512,0.00566,0.361,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SLC35F2","IOX_1",0.448,0.0247,-0.494,0.052,-2.92,0.00345,0.00411,0.361,"+/0","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["UGP2","VER_155008",-0.29,0.16,0.662,0.00524,3.13,0.00176,0.00222,0.361,"0/+","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["CYB5A","Losmapimod",-0.121,0.563,0.764,0.000563,3.23,1.25E-3,0.00188,0.362,"0/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["STAT4","Radotinib",-0.407,0.0432,0.53,0.0348,2.92,3.47E-3,0.00414,0.362,"-/+","ABL, PDGFR inhibitor","ABL1;PDGFRA;PDGFRB","Kinase inhibitor"]
["BAG6","TGR_1202",0.587,0.00205,-0.294,0.269,-2.79,0.00529,0.00582,0.363,"+/0","PI3Kdelta inhibitor","PIK3CD","Kinase inhibitor"]
["ITIH3","Prexasertib",-0.698,0.000104,0.252,0.347,3.2,0.00135,0.00187,0.363,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["MED7","Quizartinib",0.613,0.00112,-0.385,0.14,-3.2,0.00137,0.00188,0.364,"+/0","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["PAPOLG","ABT_751",0.522,7.43E-3,-0.504,0.0467,-3.24,0.00119,0.00178,0.364,"+/-","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["ADD1","AZD_5438",-0.312,0.129,0.572,0.0206,2.78,0.00542,0.00597,0.365,"0/+","CDK1, 2, 9 inhibitor","CDK1;CDK2;CDK9","Kinase inhibitor"]
["LSM7","Daunorubicin",0.198,0.342,-0.725,1.49E-3,-3.2,1.39E-3,1.92E-3,0.365,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["ZHX3","GDC_0084",-0.369,0.0698,0.607,0.0127,3.12,1.83E-3,0.00229,0.365,"0/+","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["CLEC2B","Altiratinib",0.585,0.00213,-0.417,0.108,-3.18,0.00145,2.15E-3,0.366,"+/0","MET, Tie-2 inhibitor","MET;NTRK1;NTRK3;NTRK2;TEK;FLT3;KIT;KDR","Kinase inhibitor"]
["TOB1","Navitoclax",-0.286,0.166,0.617,0.0109,2.9,0.00375,4.45E-3,0.366,"0/+","Bcl-2,Bcl-XL inhibitor","BCL2;BCL2L2;BAD;BCL2L1;MCL1","Apoptotic modulator"]
["MPHOSPH9","Nelarabine",0.201,0.335,-0.718,1.75E-3,-3.16,1.56E-3,0.0021,0.367,"0/-","Antimetabolite, Nucleoside analog, DNA, RNA synth inhibitor","DNA","Conv.Chemo"]
["KCTD6","PD0325901",0.668,0.000266,-0.291,0.274,-3.16,1.57E-3,0.00212,0.367,"+/0","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["CAPZB","Bryostatin_1",-0.176,0.399,0.658,0.0056,2.76,0.0057,0.00624,0.368,"0/+","PKC activator","PRKCE;PRKCA;PRKCE;PRKD1;CASP8","Kinase inhibitor"]
["AAMP","Galiellalactone",0.195,0.351,-0.646,0.00681,-2.76,0.00573,6.28E-3,0.368,"0/-","STAT3-DNA interaction inhibitor","STAT3","Other"]
["HIKESHI","Alisertib",0.121,0.564,-0.749,8.43E-4,-3.12,1.8E-3,0.0025,0.368,"0/-","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["CIAPIN1","Oxaliplatin",0.579,0.0024,-0.418,0.107,-3.16,1.56E-3,0.00228,0.369,"+/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["NGDN","Clomifene",0.217,0.298,-0.719,0.00169,-3.22,0.00129,1.89E-3,0.369,"0/-","Selective estrogen receptor modulator","ESR1;SHBG","Hormone therapy"]
["TMEM70","Hydroxyurea",0.312,0.129,-0.595,0.0151,-2.88,3.98E-3,0.00469,0.369,"0/-","Antineoplastic agent","RRM1","Conv.Chemo"]
["ASAP2","Sonidegib",-0.481,0.015,0.413,0.112,2.75,0.0059,6.45E-3,0.37,"-/0","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["RPAP1","Gemcitabine",-0.15,0.475,-0.874,{"v":9.64e-06,"d":"9.64E-06"},-3.43,0.00061,1.01E-3,0.37,"0/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["ARMCX5","AMG_925",0.268,0.195,-0.596,0.0149,-2.75,0.006,0.00654,0.371,"0/-","FLT3, CDK4 inhibitor","FLT3;CDK4","Kinase inhibitor"]
["MICU2","AZD8055",-0.327,0.111,0.642,0.00736,3.15,1.66E-3,0.0022,0.371,"0/+","mTOR inhibitor","MTOR","Kinase inhibitor"]
["ST3GAL4","Sirolimus",-0.127,0.546,0.705,2.3E-3,2.87,0.0041,0.00482,0.371,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["TNKS1BP1","NVP_CGM097",0.225,0.28,-0.649,0.00656,-2.86,0.00419,0.00491,0.371,"0/-","p53-MDM2 inhibitor","TP53;MDM2","Apoptotic modulator"]
["C5orf22","Idarubicin",0.347,0.0897,-0.536,0.0323,-2.75,0.00605,0.00659,0.372,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["APLP2","Panobinostat",-0.286,0.166,0.582,0.0181,2.74,6.13E-3,0.00668,0.372,"0/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["ZNF236","Salinomycin",0.405,0.0448,-0.571,0.021,-3.08,0.00206,0.00255,0.372,"+/-","Ionophore","ABCB1","Other"]
["ALYREF","Tacrolimus",0.29,0.16,-0.576,0.0196,-2.73,0.00637,0.00689,0.373,"0/-","binds FKBP12, causes inhibition of calcineurin","FKBP1A","Rapalog"]
["SLC5A3","Capmatinib",-0.311,0.13,0.587,0.0169,2.84,0.00448,0.00521,0.373,"0/+","MET inhibitor","MET","Kinase inhibitor"]
["TMEM209","AZD_5438",-0.299,0.147,0.595,0.015,2.84,0.0045,0.00522,0.373,"0/+","CDK1, 2, 9 inhibitor","CDK1;CDK2;CDK9","Kinase inhibitor"]
["CABLES1","OSU_03012",-0.446,0.0254,0.441,0.0872,2.73,0.00641,6.94E-3,0.374,"-/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["CYB5B","Perifosine",0.133,0.527,-0.742,0.000999,-3.11,0.00186,2.66E-3,0.374,"0/-","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["PHPT1","Topotecan",-0.584,0.00217,0.419,0.106,3.19,0.00144,0.00208,0.374,"-/0","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["PCYOX1","Tamatinib",-0.0727,0.73,0.777,0.000399,3.17,1.5E-3,2.16E-3,0.374,"0/+","SYK inhibitor","SYK","Kinase inhibitor"]
["TARDBP","Gemcitabine",0.308,0.134,-0.584,0.0175,-2.82,0.00477,0.00549,0.374,"0/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["AKR1A1","BMS863233",-0.275,0.184,0.586,0.0172,2.72,0.00646,0.007,0.375,"0/+","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["CPNE2","A_419259",-0.265,0.201,0.673,0.00429,3.11,1.89E-3,0.00269,0.375,"0/+","HCK and other SRC family kinase inhibitor","SRC;LCK;LYN;HCK","Kinase inhibitor"]
["SOS1","Cladribine",-0.516,0.00821,0.393,0.132,2.82,0.0048,0.00552,0.375,"-/0","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["ALKBH2","Prexasertib",0.35,0.0867,-0.526,0.0363,-2.71,0.00663,0.00717,0.376,"0/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["SDR39U1","Prexasertib",-0.839,{"v":1.65e-07,"d":"1.65E-07"},-0.0267,0.922,3.4,0.000671,0.0011,0.376,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["UGGT1","Ridaforolimus",-0.515,0.00838,0.464,0.0702,3.07,0.00217,0.00268,0.376,"-/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["XRCC2","Mercaptopurine",0.366,0.0723,-0.597,0.0147,-3.06,0.00219,0.00271,0.376,"0/-","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["C9orf64","Eribulin",0.219,0.293,-0.619,0.0105,-2.71,0.00682,0.00734,0.377,"0/-","Mitotic inhibitor, microtubule depolymerizer","TUBB1","Conv.Chemo"]
["ACAA2","Ridaforolimus",-0.356,0.0804,0.517,0.0402,2.7,0.0069,0.00742,0.378,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["CDC42BPA","Acalabrutinib",-0.481,0.015,0.505,0.0458,3.09,0.00201,0.00285,0.378,"-/+","BTK inhibitor","BTK","Kinase inhibitor"]
["WDCP","OSU_03012",0.586,0.0021,-0.376,0.151,-3.05,2.3E-3,0.00283,0.378,"+/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["PIAS2","Nilotinib",0.588,1.97E-3,-0.403,0.122,-3.15,0.00163,2.32E-3,0.379,"+/0","ABL inhibitor","ABL1;KIT","Kinase inhibitor"]
["ARID2","Spebrutinib",0.45,0.0239,-0.428,0.0984,-2.69,0.00707,0.00759,0.38,"+/0","BTK inhibitor","BTK","Kinase inhibitor"]
["ABHD16A","GSK_461364",-0.546,0.0048,0.318,0.231,2.69,0.00715,0.00765,0.38,"-/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["SNX19","GSK_461364",-0.404,0.0452,0.5,0.0486,2.79,0.0052,0.00595,0.38,"-/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["ASNS","Vinblastine",0.384,0.0583,-0.49,0.0539,-2.69,0.00715,0.00767,0.381,"0/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["RPS4X","A_1210477",-0.261,0.208,0.724,0.00153,3.38,0.000725,1.17E-3,0.381,"0/+","MCL-1 inhibitor","MCL1","Apoptotic modulator"]
["TFG","Pomalidomide",-0.305,0.138,0.578,0.019,2.79,0.00531,0.00606,0.381,"0/+","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["EIF4ENIF1","Navitoclax",-0.174,0.407,0.713,1.92E-3,3.06,0.00224,0.00305,0.382,"0/+","Bcl-2,Bcl-XL inhibitor","BCL2;BCL2L2;BAD;BCL2L1;MCL1","Apoptotic modulator"]
["LRR1","8_amino_adenosine",0.438,0.0284,-0.543,0.0297,-3.08,0.00204,2.66E-3,0.382,"+/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["RFWD3","Oxaliplatin",0.492,0.0124,-0.559,0.0244,-3.35,0.000822,0.0013,0.382,"+/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["ZNF180","Trametinib",-0.415,0.0393,0.549,0.0278,3.02,0.0025,0.00303,0.382,"-/+","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["INIP","AZD_5363",0.388,0.0555,-0.582,0.0179,-3.07,0.00211,0.00274,0.383,"0/-","AKT inhibitor","AKT1;AKT2;AKT3;ROCK2","Kinase inhibitor"]
["ZNF280C","Prexasertib",0.441,0.0275,-0.525,0.0366,-3.02,0.00253,0.00307,0.383,"+/-","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["AAR2","AZD_1080",0.37,0.0688,-0.499,0.0489,-2.68,0.00742,0.00793,0.384,"0/-","GSK3 inhibitor","GSK3B;GSK3A","Kinase inhibitor"]
["SNTB2","GSK_1070916",-0.1,0.634,0.701,2.49E-3,2.77,0.00558,0.00634,0.384,"0/+","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["UTP4","Glesatinib",0.483,0.0145,-0.483,0.0579,-3.01,0.00259,3.13E-3,0.384,"+/0","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["ERLEC1","Losmapimod",-0.435,0.0298,-0.911,{"v":9.46e-07,"d":"9.46E-07"},-3.05,2.3E-3,0.00312,0.385,"-/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["SMARCA5","Navitoclax",-0.46,0.0207,0.438,0.09,2.76,0.00573,0.00649,0.385,"-/0","Bcl-2,Bcl-XL inhibitor","BCL2;BCL2L2;BAD;BCL2L1;MCL1","Apoptotic modulator"]
["ZFYVE19","Dactolisib",-0.461,0.0203,0.5,0.0487,3,0.00274,3.29E-3,0.385,"-/+","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;ATR;RPS6KB1","Kinase inhibitor"]
["FUCA1","WEHI_539",0.357,0.0801,-0.599,0.0142,-3.04,0.00234,0.00317,0.386,"0/-","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["RPS6KA4","Ridaforolimus",-0.382,0.0598,0.64,0.00755,3.32,0.000908,1.42E-3,0.386,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["GALNT1","Fluorouracil",-0.325,0.112,0.62,0.0104,3.04,0.00238,0.00323,0.387,"0/+","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","TYMS","Conv.Chemo"]
["SOD1","Entinostat",-0.518,0.00805,0.372,0.156,2.75,0.00588,0.00664,0.387,"-/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["VCPIP1","Tivantinib",-0.49,0.0129,0.469,0.0668,2.99,2.82E-3,0.00338,0.387,"-/0","MET inhibitor","MET","Kinase inhibitor"]
["GNPDA2","Valrubicin",-0.155,0.458,0.718,1.72E-3,3.03,0.00242,0.00327,0.388,"0/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["PCCA","OTS167",-0.258,0.212,0.676,0.00404,3.11,1.9E-3,2.66E-3,0.388,"0/+","MELK inhibitor","MELK","Kinase inhibitor"]
["SLC25A25","Sorafenib",-0.505,0.0101,0.384,0.142,2.74,0.00606,0.00682,0.388,"-/0","BRAF, FGFR-1, VEGFR-2 and -3, PDGFR-beta, KIT, and FLT3 inhibitor","BRAF;FGFR1;KDR;FLT3;KIT;FLT4;PDGFRB","Kinase inhibitor"]
["CPSF2","Navitoclax",-0.286,0.166,0.646,0.00688,3.04,0.00239,3.3E-3,0.389,"0/+","Bcl-2,Bcl-XL inhibitor","BCL2;BCL2L2;BAD;BCL2L1;MCL1","Apoptotic modulator"]
["PALM2AKAP2","Acitretin",0.456,0.022,-0.531,0.0345,-3.1,0.00196,0.00273,0.389,"+/-","Retinoic acid receptor agonist","RARA;RARB;RXRA;RXRB;RXRG","Differentiating.epigenetic modifier"]
["TRIM4","Erlotinib",5.3E-3,0.98,0.781,0.000358,2.98,0.0029,3.46E-3,0.389,"0/+","EGFR inhibitor","EGFR","Kinase inhibitor"]
["FLNC","ONX_0914",-0.256,0.216,0.662,0.00525,3.02,0.0025,0.00336,0.39,"0/+","LMP7 (immunoproteasome)","PSMB8","Protease.proteasome inhibitor"]
["LPIN2","PF_06463922",-0.163,0.436,0.717,0.00177,3.05,2.31E-3,2.97E-3,0.39,"0/+","ALK, ROS1 inhibitor","ALK;LTK;FER;FES;PTK2B;TNK2;PTK2;NTRK1;NTRK2;NTRK3;FRK;ROS1","Kinase inhibitor"]
["PUM1","GSK_461364",0.502,0.0105,-0.532,0.0338,-3.28,1.06E-3,0.00161,0.39,"+/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["ANKRD13C","AZD7762",0.515,0.00847,-0.344,0.192,-2.65,0.00797,0.00846,0.391,"+/0","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["SAMHD1","Erastin",-0.33,0.107,0.666,0.00488,3.27,1.06E-3,0.00161,0.391,"0/+","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["TCIRG1","NVP_BGT226",-0.295,0.152,0.573,0.0203,2.73,0.00625,0.00701,0.391,"0/+","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CG;MTOR","Kinase inhibitor"]
["TFIP11","Imiquimod",-0.144,0.492,0.67,0.00453,2.73,0.00631,0.00706,0.392,"0/+","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["ZFAND3","Finasteride",-0.0263,0.901,0.766,0.000543,2.96,0.00305,3.63E-3,0.392,"0/+","type II 5-alpha reductase inhibitor","SRD5A2","Hormone therapy"]
["ALKBH8","Tipifarnib",0.311,0.13,-0.539,0.0313,-2.64,0.00824,0.00873,0.393,"0/-","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["CASP8AP2","BAY_87_2243",0.282,0.172,-0.56,0.024,-2.64,0.00832,0.00879,0.393,"0/-","HIF1alpha inhibitor","HIF1A","Differentiating.epigenetic modifier"]
["MAP2K1","Dactinomycin",-0.325,0.113,0.619,0.0105,3.03,0.00243,0.00312,0.393,"0/+","RNA and DNA synthesis inhibitor","DNA","Conv.Chemo"]
["SF3B3","Methotrexate",0.463,0.0198,-0.423,0.103,-2.72,0.00649,0.00723,0.393,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["AKT1S1","Mercaptopurine",0.236,0.256,-0.592,0.0156,-2.63,8.43E-3,0.00891,0.394,"0/-","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["POLE3","Onalespib",0.502,0.0106,-0.481,0.0591,-3.08,0.0021,0.00289,0.394,"+/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["WT1","Megestrol_acetate",0.601,1.49E-3,-0.324,0.22,-2.95,0.0032,0.00378,0.394,"+/0","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["AK6","Losmapimod",0.0377,0.858,0.743,0.000966,2.63,0.00853,0.009,0.395,"0/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["GLB1","Ridaforolimus",-0.498,0.0112,0.464,0.0703,3,0.0027,0.00361,0.395,"-/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["PYHIN1","GSK269962",-0.497,0.0114,0.528,0.0357,3.24,0.00121,1.81E-3,0.395,"-/+","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["RAF1","Losmapimod",0.0796,0.705,-0.78,0.000362,-3.22,0.00129,1.92E-3,0.395,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["UTRN","UNC0638",-0.458,0.0212,0.488,0.0551,2.94,0.00327,0.00386,0.395,"-/0","G9a, GLP inhibitor","EHMT2","Differentiating.epigenetic modifier"]
["ZNF446","Sonidegib",-0.491,0.0128,0.454,0.0776,2.93,0.00335,0.00395,0.395,"-/0","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["ZNF367","Perifosine",0.0264,0.9,0.78,0.000363,2.91,0.00356,0.00417,0.395,"0/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["B3GLCT","PF_03758309",-0.492,0.0125,0.364,0.166,2.63,0.00858,0.00906,0.396,"-/0","PAK4 inhibitor","PAK4","Kinase inhibitor"]
["DDX3X","Altiratinib",0.497,0.0115,-0.46,0.0727,-2.98,0.00287,0.00385,0.396,"+/0","MET, Tie-2 inhibitor","MET;NTRK1;NTRK3;NTRK2;TEK;FLT3;KIT;KDR","Kinase inhibitor"]
["GLTP","Cytarabine.Idarubicin",-0.298,0.148,0.629,0.00908,2.99,0.00277,0.00369,0.396,"0/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["EXOSC5","Quisinostat",-0.416,0.0385,0.538,0.0316,2.99,0.00283,0.00375,0.397,"-/+","HDAC inhibitor","HDAC1;HDAC2;HDAC4;HDAC10;HDAC11","Differentiating.epigenetic modifier"]
["SCD","GSK_2334470",0.489,0.013,-0.526,0.0365,-3.2,0.00138,0.00201,0.397,"+/-","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["SRSF9","Danusertib",0.263,0.204,-0.589,0.0163,-2.7,0.00685,7.6E-3,0.397,"0/-","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["ZNF219","Taselisib",0.062,0.769,-0.742,1.01E-3,-2.9,0.00368,4.28E-3,0.397,"0/-","PI3K alpha, delta, (gamma) selective inhibitor","PIK3CA;PIK3CD;PIK3CG","Kinase inhibitor"]
["EIF2AK4","Methylprednisolone",0.184,0.378,-0.694,0.00287,-2.98,0.00291,0.00383,0.398,"0/-","Glucocorticoid, immunomodulatory agent","NR3C1","Immunomodulatory"]
["MAP2K4","Pemetrexed",-0.423,0.0354,0.54,0.031,3.01,0.00258,0.00326,0.398,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["OTUD1","Erastin",0.396,0.0498,-0.568,0.0217,-3.04,0.00235,0.00319,0.398,"+/-","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["MYEF2","Fimepinostat_CUDC_907",0.427,0.0334,-0.539,0.0311,-3.03,2.47E-3,0.00333,0.398,"+/-","HDAC1, 2, 3, 10  and 11, PI3Kalpha inhibitor","HDAC1;HDAC2;HDAC3;HDAC10;HDAC11;PIK3CA","Differentiating.epigenetic modifier"]
["NCKAP5L","Quisinostat",-0.514,0.00862,0.451,0.0799,3.01,0.00261,0.0035,0.398,"-/0","HDAC inhibitor","HDAC1;HDAC2;HDAC4;HDAC10;HDAC11","Differentiating.epigenetic modifier"]
["RING1","MK_8745",-0.258,0.212,0.693,0.0029,3.2,0.00138,0.00203,0.398,"0/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["VRK1","8_amino_adenosine",0.251,0.226,-0.638,0.00781,-2.89,0.00383,0.00442,0.398,"0/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["AASDHPPT","Sirolimus",0.0598,0.777,-0.693,0.00289,-2.61,0.00895,0.00942,0.399,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ELMSAN1","Cisplatin",-0.436,0.0293,0.517,0.0405,2.97,2.98E-3,0.0039,0.399,"-/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["TDP2","Prexasertib",0.471,0.0174,-0.406,0.119,-2.69,0.00708,0.00783,0.399,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["TNPO2","Hydroxyurea",-0.46,0.0206,0.416,0.109,2.69,0.00717,0.00793,0.399,"-/0","Antineoplastic agent","RRM1","Conv.Chemo"]
["STRN4","Carboplatin",-0.276,0.182,0.575,0.0199,2.68,0.00734,0.00811,0.399,"0/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["CENPM","8_amino_adenosine",0.342,0.0945,-0.592,0.0158,-2.96,0.00305,0.00406,0.4,"0/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["CD248","AZD1208",-0.309,0.133,0.615,0.0113,2.96,0.00307,0.00409,0.4,"0/+","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["PLXNC1","Tasquinimod",-0.283,0.171,0.639,0.00772,2.99,0.00276,0.00368,0.4,"0/+","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["ATP6V1C1","Varlitinib",-0.214,0.305,0.599,0.0141,2.6,0.00934,0.00976,0.401,"0/+","EGFR HER2 inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["NUF2","Prexasertib",0.635,0.000654,-0.288,0.28,-2.99,2.81E-3,0.00373,0.401,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["SSH3","Quizartinib",0.494,0.0121,-0.376,0.151,-2.68,0.00744,0.00819,0.401,"+/0","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["AXIN1","Dactinomycin",0.146,0.487,-0.642,0.00737,-2.59,0.00946,0.0099,0.402,"0/-","RNA and DNA synthesis inhibitor","DNA","Conv.Chemo"]
["RAP1A","Pemetrexed",-0.644,5.13E-4,0.335,0.205,3.18,1.47E-3,2.14E-3,0.402,"-/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["SLC30A5","PAC_1",-0.332,0.105,0.53,0.0346,2.67,0.00752,0.00829,0.402,"0/+","procaspase-3 activator","CASP3","Apoptotic modulator"]
["AGFG2","Triapine",-0.445,0.0259,0.404,0.12,2.59,0.00952,0.00996,0.403,"-/0","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["CMPK1","Mercaptopurine",-0.331,0.106,0.596,0.0148,2.95,0.00319,0.00421,0.403,"0/+","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["CCNY","ABT_751",-0.568,0.00307,0.365,0.164,2.94,3.32E-3,0.00437,0.403,"-/0","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["G3BP2","AZD7762",0.36,0.0773,-0.575,0.0197,-2.95,0.00317,4.13E-3,0.403,"0/-","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["GNL2","AZD1775",0.605,0.00136,-0.317,0.232,-2.94,0.00326,0.00423,0.403,"+/0","Wee1 inhibitor","WEE1","Kinase inhibitor"]
["PCYOX1L","Pemetrexed",-0.416,0.0385,0.533,0.0334,2.97,0.00301,0.00395,0.403,"-/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["TIPIN","PAC_1",0.375,0.0646,-0.492,0.0531,-2.67,0.00767,0.00844,0.403,"0/0","procaspase-3 activator","CASP3","Apoptotic modulator"]
["ZNF142","8_amino_adenosine",0.47,0.0177,-0.455,0.0767,-2.86,0.00421,4.81E-3,0.403,"+/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["ANKRD46","A_419259",0.327,0.111,-0.511,0.0432,-2.58,0.00981,0.0102,0.404,"0/-","HCK and other SRC family kinase inhibitor","SRC;LCK;LYN;HCK","Kinase inhibitor"]
["HACE1","LY3009120",-0.248,0.232,0.647,0.00671,2.93,0.00342,0.0044,0.404,"0/+","Pan-RAF, (Pan-HER inhibitor)","BRAF;RAF1","Kinase inhibitor"]
["PRRC2B","AZD_8186",0.566,0.00321,-0.427,0.099,-3.14,0.00171,0.00244,0.404,"+/0","PI3K beta inhibitor","PIK3CG","Kinase inhibitor"]
["SACM1L","WEHI_539",0.457,0.0215,-0.538,0.0317,-3.13,1.75E-3,2.48E-3,0.404,"+/-","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["RAD54L","Topotecan",0.427,0.0333,-0.557,0.025,-3.1,0.00193,0.0027,0.404,"+/-","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["APOM","Rigosertib",-0.731,{"v":3.35e-05,"d":"3.35E-05"},-0.0285,0.917,2.58,0.00994,0.0103,0.405,"-/0","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["GRB2","E7820",-0.598,1.58E-3,0.32,0.227,2.92,3.48E-3,4.47E-3,0.405,"-/0","Integrin alpha2 expression inhibitor","ITGA2","Other"]
["TMBIM6","Ridaforolimus",-0.417,0.0379,0.45,0.0801,2.66,0.00788,0.00864,0.405,"-/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["INPP4A","Talazoparib",-0.378,0.0624,0.571,0.0209,2.99,0.00277,0.00351,0.406,"0/+","PARP1 and 2 inhibitor","PARP1;PARP2","Differentiating.epigenetic modifier"]
["PCDH9","Seliciclib",0.477,0.0159,-0.474,0.0636,-2.96,0.0031,0.00407,0.406,"+/0","CDK2, 7, 9 inhibitor","CDK2;CDK1;CDK5;MAPK1;MAPK3","Kinase inhibitor"]
["ARMC8","Cabazitaxel",-0.44,0.0277,0.403,0.122,2.57,0.0101,0.0105,0.407,"-/0","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["ATXN2","Cytarabine.Idarubicin",0.23,0.268,-0.58,0.0184,-2.57,0.0103,0.0107,0.407,"0/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["CENPN","GSK_461364",0.361,0.0765,-0.566,0.0223,-2.91,0.00357,4.64E-3,0.407,"0/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["PIGS","Ridaforolimus",-0.426,0.0337,0.521,0.0386,2.95,3.16E-3,4.13E-3,0.407,"-/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["STAU1","AZD1775",0.491,0.0127,-0.371,0.157,-2.65,0.00804,0.00882,0.407,"+/0","Wee1 inhibitor","WEE1","Kinase inhibitor"]
["ZW10","PF_670462",0.309,0.133,-0.589,0.0164,-2.84,0.00446,0.00509,0.407,"0/-","CK1epsilon and CK1delta inhibitor","CSNK1D;CSNK1E","Kinase inhibitor"]
["VARS1","Floxuridine",0.649,0.000447,-0.213,0.428,-2.83,4.64E-3,0.00525,0.407,"+/0","Antimetabolite, Analog of 5-fluorouracil","TYMS","Conv.Chemo"]
["AKIRIN1","Ponatinib",0.276,0.182,-0.545,0.029,-2.56,0.0105,0.011,0.408,"0/-","Broad TK inhibitor","ABL1;PDGFRA;KDR;FGFR1;SRC;KIT","Kinase inhibitor"]
["ARL6IP4","Filanesib",0.383,0.0587,-0.454,0.0772,-2.55,0.0106,0.011,0.408,"0/0","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["GPN1","Olaparib",0.0505,0.811,-0.746,{"v":0.0009,"d":"9.00E-04"},-2.9,0.00372,0.00475,0.408,"0/-","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["KCNAB2","E7820",-0.44,0.0277,0.516,0.0407,2.98,0.00286,0.0036,0.408,"-/+","Integrin alpha2 expression inhibitor","ITGA2","Other"]
["TBL1X","ML390",0.354,0.0823,-0.503,0.0472,-2.64,0.00831,0.00909,0.408,"0/-","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["C11orf58","AT9283",0.306,0.137,-0.519,0.0394,-2.55,0.0108,0.0112,0.409,"0/-","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["LAT","Romidepsin",0.356,0.081,-0.585,0.0173,-2.98,0.0029,3.65E-3,0.409,"0/-","HDAC inhibitor","HDAC1;HDAC2","Differentiating.epigenetic modifier"]
["POLG","Rocilinostat",-0.224,0.282,0.665,0.0049,2.94,0.00323,0.00422,0.409,"0/+","HDAC6 selective inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["USP32","Entinostat",-0.455,0.0222,0.459,0.0735,2.82,0.00474,0.00536,0.409,"-/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["AFF4","Imatinib",0.215,0.302,-0.587,0.0169,-2.55,0.0109,0.0112,0.41,"0/-","ABL, Kit, PDGFRB inhibitor","ABL1","Kinase inhibitor"]
["SMIM26","BI_2536",0.546,0.00478,-0.3,0.26,-2.63,0.00845,0.00923,0.41,"+/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["ADCK2","PAC_1",0.00939,0.964,-0.707,0.00221,-2.54,0.0109,0.0113,0.411,"0/-","procaspase-3 activator","CASP3","Apoptotic modulator"]
["EIF4G1","Galiellalactone",0.139,0.508,-0.701,2.48E-3,-2.88,0.00391,0.00495,0.411,"0/-","STAT3-DNA interaction inhibitor","STAT3","Other"]
["PSMC1","Raltitrexed",0.486,0.0138,-0.5,0.0488,-3.09,0.00203,2.82E-3,0.411,"+/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["SMAD1","Erastin",0.449,0.0243,-0.409,0.116,-2.62,0.0087,0.00948,0.411,"+/0","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["WDR34","Sirolimus",0.309,0.133,-0.582,0.0181,-2.81,0.00491,0.00552,0.411,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ABHD4","AZD_5438",-0.181,0.387,0.608,0.0126,2.54,0.0112,0.0115,0.412,"0/+","CDK1, 2, 9 inhibitor","CDK1;CDK2;CDK9","Kinase inhibitor"]
["NCOA5","GSK_690693",0.465,0.0193,-0.479,0.0604,-2.93,0.00339,0.0044,0.412,"+/0","AKT, PKA, PKC inhibitor","AKT1;AKT2;AKT3;PRKCE;PRKCB;PRKCD;PRKCH;PRKCQ;PRKX;PRKG1","Kinase inhibitor"]
["SIAH1","Fimepinostat_CUDC_907",-0.22,0.292,0.6,0.014,2.62,0.00882,0.00959,0.412,"0/+","HDAC1, 2, 3, 10  and 11, PI3Kalpha inhibitor","HDAC1;HDAC2;HDAC3;HDAC10;HDAC11;PIK3CA","Differentiating.epigenetic modifier"]
["TRIP4","Flutamide",0.145,0.49,-0.684,3.48E-3,-2.81,0.00498,0.00559,0.412,"0/-","Nonsteroidal antiandrogen","AR;AHR;NR1I2","Hormone therapy"]
["GALNT2","Ganetespib",0.391,0.0536,-0.533,0.0336,-2.88,0.00401,0.00507,0.413,"0/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["SNTB1","Doramapimod",-0.17,0.416,0.63,0.00888,2.61,0.00902,0.00979,0.413,"0/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["TIMM9","Tivozanib",-0.619,9.68E-4,0.187,0.487,2.61,0.00905,0.00982,0.413,"-/0","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["AKR1A1","Entinostat",-0.524,0.00718,0.294,0.269,2.53,0.0114,0.0118,0.414,"-/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["CHD3","VS_4718",-0.369,0.0695,0.552,0.0267,2.88,0.00395,0.0051,0.414,"0/+","FAK inhibitor","PTK2","Kinase inhibitor"]
["MGST3","Selinexor",0.0174,0.934,0.783,0.000338,2.96,0.00309,0.00386,0.414,"0/+","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["ZSWIM1","Milciclib",8.09E-3,0.969,-0.75,0.000824,-2.8,0.00506,0.00567,0.414,"0/-","CDK2 inhibitor","CDK2;CDK4;CDK5;CDK7;NTRK1","Kinase inhibitor"]
["ARL6IP4","AZD_5438",0.289,0.162,-0.527,0.036,-2.52,0.0116,0.012,0.415,"0/-","CDK1, 2, 9 inhibitor","CDK1;CDK2;CDK9","Kinase inhibitor"]
["GALNT2","Everolimus",0.202,0.334,-0.662,0.0052,-2.86,0.00422,0.00529,0.415,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["KLHL20","Quizartinib",0.246,0.236,-0.651,0.00626,-2.94,0.00327,0.00405,0.415,"0/-","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["SH2D3C","AT9283",-0.418,0.0377,0.435,0.0925,2.6,0.00924,0.01,0.415,"-/0","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["ATIC","BX_912",0.415,0.0392,-0.413,0.112,-2.52,0.0118,0.0121,0.416,"+/0","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["ASB8","Mocetinostat",0.113,0.592,-0.645,0.00703,-2.51,0.012,0.0123,0.416,"0/-","HDAC inhibitor (HDAC1 and 2-selective)","HDAC1;HDAC2;HDAC3;HDAC11","Differentiating.epigenetic modifier"]
["PHF8","MK_8745",0.271,0.189,-0.628,0.00916,-2.91,3.65E-3,0.0047,0.416,"0/-","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["SMU1","Dactolisib",0.0697,0.74,-0.686,0.00337,-2.6,0.00933,0.0101,0.416,"0/-","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;ATR;RPS6KB1","Kinase inhibitor"]
["BAZ1A","Litronesib",0.417,0.0382,-0.409,0.116,-2.51,0.012,0.0124,0.417,"+/0","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["GUCY1A1","Acitretin",0.186,0.374,-0.669,0.00458,-2.85,0.00436,5.45E-3,0.417,"0/-","Retinoic acid receptor agonist","RARA;RARB;RXRA;RXRB;RXRG","Differentiating.epigenetic modifier"]
["FTO","Cerdulatinib",-0.122,0.562,0.702,0.00244,2.84,0.00451,0.0056,0.417,"0/+","JAK, SYK inhibitor","JAK1;JAK2;JAK3;TYK2;SYK","Kinase inhibitor"]
["TCF25","NMS_873",0.464,0.0196,-0.385,0.141,-2.59,0.00951,0.0103,0.417,"+/0","p97, VCP inhibitor","VCP","Other"]
["LAMTOR2","PF_670462",-0.289,0.161,0.622,0.0101,2.93,0.00336,0.00417,0.418,"0/+","CK1epsilon and CK1delta inhibitor","CSNK1D;CSNK1E","Kinase inhibitor"]
["KRT78","Lonafarnib",-0.309,0.133,0.608,0.0124,2.93,0.00337,0.00417,0.418,"0/+","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["ACOT2","Clomifene",-0.453,0.0229,0.368,0.161,2.5,0.0124,0.0127,0.419,"-/0","Selective estrogen receptor modulator","ESR1;SHBG","Hormone therapy"]
["FERMT1","ARV_825",-0.393,0.0519,0.519,0.0393,2.83,0.00463,0.00574,0.419,"0/+","BET-targeting PROTAC","BRD4","Differentiating.epigenetic modifier"]
["PUS3","Flutamide",-0.0713,0.735,0.759,0.000647,3.05,2.31E-3,0.00317,0.419,"0/+","Nonsteroidal antiandrogen","AR;AHR;NR1I2","Hormone therapy"]
["TAF5L","Buparlisib",-0.646,0.00049,0.136,0.616,2.59,0.00972,0.0105,0.419,"-/0","PI3K inhibitor, pan-class I","PIK3CA;PIK3CB;PIK3CG;PIK3CD;MTOR;PIK3C3","Kinase inhibitor"]
["ABHD2","Abexinostat",0.237,0.255,-0.559,0.0245,-2.49,0.0126,0.0129,0.42,"0/-","HDAC1 selective inhibitor","HDAC1","Differentiating.epigenetic modifier"]
["CD47","AZD3965",-0.297,0.15,0.601,0.0138,2.86,0.00424,0.00543,0.42,"0/+","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["CTNNBIP1","Trifluridine",-0.726,{"v":4.01e-05,"d":"4.01E-05"},0.0763,0.779,2.85,0.0044,0.00561,0.42,"-/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["CCDC88A","Cisplatin",0.141,0.5,-0.691,0.00301,-2.84,0.00453,0.00575,0.42,"0/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["MANEA","UNC0638",-0.535,0.00581,0.402,0.122,2.93,0.00342,0.00422,0.42,"-/0","G9a, GLP inhibitor","EHMT2","Differentiating.epigenetic modifier"]
["SLU7","Danusertib",0.281,0.174,-0.547,0.0282,-2.58,0.00984,0.0106,0.42,"0/-","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["CLCC1","Ribociclib",-0.434,0.0301,0.483,0.0582,2.83,0.00459,0.00582,0.421,"-/0","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["CENPH","Hydroxyurea",0.349,0.0873,-0.556,0.0254,-2.83,4.62E-3,0.00585,0.421,"0/-","Antineoplastic agent","RRM1","Conv.Chemo"]
["KIF2C","BIIB021",0.406,0.0439,-0.529,0.0351,-2.92,0.00355,0.00436,0.421,"+/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["PDIA5","GSK269962",-0.492,0.0125,0.439,0.0889,2.89,0.00391,0.00499,0.421,"-/0","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["STEAP3","Trametinib",-0.298,0.147,0.532,0.0337,2.58,0.00997,0.0107,0.421,"0/+","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["CAMK2G","WEHI_539",0.481,0.015,-0.334,0.207,-2.49,0.0128,0.0131,0.422,"+/0","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["ARPC1A","Vactosertib_TEW_7197",0.381,0.0606,-0.437,0.0903,-2.49,0.0129,0.0132,0.422,"0/0","TGF receptor ALK4, ALK5 inhibitor","TGFBR1;ACVR1B","Kinase inhibitor"]
["BLOC1S6","Cisplatin",-0.623,0.00087,0.136,0.615,2.48,0.0131,0.0134,0.422,"-/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["DONSON","IOX_1",0.355,0.0818,-0.551,0.027,-2.83,4.64E-3,0.00588,0.422,"0/-","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["PEX19","Pazopanib",-0.252,0.224,0.635,0.00819,2.88,0.00397,0.00508,0.422,"0/+","VEGFR inhibitor","FLT1;KDR;FLT4;KIT;PDGFRA;PDGFRB;CSF1R;FGFR3;ITK","Kinase inhibitor"]
["RNF167","WEHI_539",0.668,0.00026,-0.246,0.358,-3.03,2.47E-3,0.00335,0.422,"+/0","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["SLBP","Sirolimus",0.221,0.289,-0.587,0.0168,-2.57,0.0103,0.0111,0.422,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SH3BP2","Axitinib",-0.379,0.0614,0.459,0.0738,2.56,0.0105,0.0112,0.422,"0/0","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["AHSA1","Tazemetostat",0.261,0.207,-0.536,0.0323,-2.48,0.0133,0.0135,0.423,"0/-","EZH2 inhibitor","EZH2","Differentiating.epigenetic modifier"]
["AFG1L","Itraconazole",-0.192,0.358,0.585,0.0172,2.47,0.0134,0.0136,0.423,"0/+","antifungal, hedgehog signaling inhibitor","CYP51A1;CYP3A4","Other"]
["FBXW8","NVP_BGT226",0.338,0.0981,-0.556,0.0252,-2.8,0.0051,0.00622,0.423,"0/-","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CG;MTOR","Kinase inhibitor"]
["IDH3A","Venetoclax",0.413,0.0401,-0.521,0.0386,-2.91,3.65E-3,0.00449,0.423,"+/-","Bcl-2 selective inhibitor","BCL2","Apoptotic modulator"]
["REXO2","GSK650394",0.388,0.0552,-0.569,0.0213,-3.02,0.00253,0.00343,0.423,"0/-","SGK1 and 2 inhibitor","SGK1","Kinase inhibitor"]
["ABCB8","Ganetespib",0.467,0.0186,-0.343,0.193,-2.47,0.0135,0.0137,0.424,"+/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["EEF1AKMT1","Hydroxyurea",-0.431,0.0314,0.48,0.0601,2.81,0.00491,0.00617,0.424,"-/0","Antineoplastic agent","RRM1","Conv.Chemo"]
["NHLRC3","IOX_1",-0.393,0.052,0.529,0.0349,2.87,0.00408,0.0052,0.424,"0/+","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["TIMP2","Erastin",0.2,0.338,-0.597,0.0145,-2.55,0.0108,0.0115,0.424,"0/-","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["ANKRD46","FRAX486",0.258,0.214,-0.537,0.0321,-2.47,0.0136,0.0139,0.425,"0/-","PAK1, 2, 3 inhibitor","PAK1","Kinase inhibitor"]
["C16orf72","BIIB021",0.495,0.012,-0.309,0.244,-2.46,0.0138,0.014,0.425,"+/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["HCFC2","Pexidartinib",-0.437,0.0288,0.469,0.0671,2.79,0.00521,0.00634,0.425,"-/0","KIT, CSF1R, FLT3 inhibitor","CSF1R;FLT3;KIT","Kinase inhibitor"]
["HCFC1","Tipifarnib",-0.431,0.0313,0.472,0.0648,2.79,0.00534,0.00647,0.425,"-/0","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["LARS1","BMS_754807",0.222,0.286,-0.656,0.00575,-2.89,3.81E-3,0.00466,0.425,"0/-","IGF1R inhibitor","IGF1R","Kinase inhibitor"]
["PTBP1","Quisinostat",-0.656,0.00037,0.258,0.336,3,0.0027,3.62E-3,0.425,"-/0","HDAC inhibitor","HDAC1;HDAC2;HDAC4;HDAC10;HDAC11","Differentiating.epigenetic modifier"]
["SLC25A11","Rigosertib",-0.649,0.000454,0.114,0.674,2.54,0.0112,0.0119,0.425,"-/0","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["USF2","Tamatinib",-0.375,0.0646,0.518,0.0396,2.77,5.62E-3,0.00627,0.425,"0/+","SYK inhibitor","SYK","Kinase inhibitor"]
["ADAM9","Valrubicin",-0.351,0.0852,0.457,0.0752,2.46,0.0139,0.0142,0.426,"0/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["C5orf24","NVP_RAF265",0.188,0.369,-0.584,0.0176,-2.45,0.0142,0.0143,0.426,"0/-","C-Raf inhibitor, unclear MoA","RAF1;BRAF;KDR","Kinase inhibitor"]
["CDK17","Amuvatinib",0.168,0.421,-0.67,0.00454,-2.8,0.00509,0.00636,0.426,"0/-","Broad TK inhibitor","KIT;PDGFRA;FLT3","Kinase inhibitor"]
["PALM2AKAP2","CEP_37440",0.297,0.15,-0.601,0.0138,-2.86,0.00423,0.00537,0.426,"0/-","ALK inhibitor","ALK;AXL;MET;TYRO3;MERTK;KDR;DDR1","Kinase inhibitor"]
["SMNDC1","THZ2",-0.482,0.0147,0.345,0.19,2.53,0.0113,0.0121,0.426,"-/0","CDK7 inhibitor","CDK7","Kinase inhibitor"]
["C9orf40","8_amino_adenosine",0.286,0.166,-0.511,0.0433,-2.45,0.0142,0.0144,0.427,"0/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["ASB6","Docetaxel",0.388,0.0553,-0.419,0.106,-2.45,0.0144,0.0146,0.427,"0/0","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["CHM","Etoposide",-0.57,0.00293,0.32,0.226,2.8,5.11E-3,0.0064,0.427,"-/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["ECHS1","Dactolisib",-0.559,3.65E-3,0.332,0.209,2.79,0.00524,0.00654,0.427,"-/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;ATR;RPS6KB1","Kinase inhibitor"]
["CENPK","Fulvestrant",-0.167,0.424,0.667,0.00477,2.78,0.00536,0.00668,0.427,"0/+","Estrogen receptor antagonist","ESR1","Hormone therapy"]
["FYN","UCN_01",-0.236,0.256,0.623,0.00986,2.78,0.0055,0.00665,0.427,"0/+","PKCbeta, PDK1, Chk, Cdk2 inhibitor","PRKCB;PDPK1","Kinase inhibitor"]
["GNA13","Bosutinib",-0.286,0.166,0.588,0.0165,2.77,0.00561,0.00676,0.427,"0/+","ABL, Src inhibitor","ABL1;LYN;HCK;SRC;EPHB2;NTRK1;NTRK2;TXK","Kinase inhibitor"]
["SLC25A30","Aldoxorubicin",-0.352,0.0848,0.475,0.0627,2.53,0.0115,0.0122,0.427,"0/0","Topoisomerase II inhibitor, Albumin binding","TOP2A;TOP2B","Conv.Chemo"]
["TP53BP2","Bafetinib",-0.0873,0.678,-0.783,3.39E-4,-2.76,0.00583,0.00649,0.427,"0/-","ABL, Lyn inhibitor","ABL1;LYN","Kinase inhibitor"]
["ZXDC","Buparlisib",0.000143,0.999,0.745,0.000927,2.75,0.00598,0.00663,0.427,"0/+","PI3K inhibitor, pan-class I","PIK3CA;PIK3CB;PIK3CG;PIK3CD;MTOR;PIK3C3","Kinase inhibitor"]
["UBXN2B","Palbociclib",0.418,0.0376,-0.474,0.0638,-2.74,0.00605,0.00668,0.427,"+/0","Topoisomerase I inhibitor, Camptothecin analog","CDK4;CDK6","Kinase inhibitor"]
["DPH6","Sitravatinib",0.327,0.11,-0.559,0.0243,-2.78,0.00549,0.00683,0.428,"0/-","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["GLI3","Pevonedistat",-0.0811,0.7,-0.781,0.000354,-2.76,0.00571,0.00688,0.428,"0/-","NAE inhibitor","NAE1","Metabolic modifier"]
["NCKAP5L","Mivebresib",-0.352,0.0844,0.557,0.0249,2.85,0.00439,0.00554,0.428,"0/+","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["BAG6","Lonafarnib",0.515,8.43E-3,-0.275,0.302,-2.44,0.0149,0.015,0.429,"+/0","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["ARL6","Vinflunine",0.353,0.0835,-0.447,0.0826,-2.43,0.0151,0.0153,0.429,"0/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["HADHA","BMS863233",-0.41,0.042,0.485,0.057,2.76,0.00584,0.007,0.429,"-/0","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["FAM49B","Lifirafenib_BGB_283",-0.345,0.091,0.537,0.0318,2.75,0.00603,0.00721,0.429,"0/+","Raf inhibitor","RAF1;BRAF;EGFR","Kinase inhibitor"]
["PCDH9","Oxaliplatin",0.644,0.000508,-0.226,0.4,-2.85,0.00444,0.00559,0.429,"+/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["PRDX1","Fingolimod",0.434,0.0303,-0.523,0.0378,-2.99,0.00283,3.79E-3,0.429,"+/-","S1PR antagonist","S1PR1","Other"]
["TBCCD1","PCI_34051",0.591,0.00185,-0.199,0.461,-2.52,0.0118,0.0125,0.429,"+/0","HDAC8 inhibitor","HDAC8","Differentiating.epigenetic modifier"]
["AP1G1","Seliciclib",0.4,0.0476,-0.401,0.124,-2.43,0.0153,0.0154,0.43,"+/0","CDK2, 7, 9 inhibitor","CDK2;CDK1;CDK5;MAPK1;MAPK3","Kinase inhibitor"]
["BCAS4","BI_2536",0.145,0.488,-0.605,0.013,-2.42,0.0154,0.0155,0.43,"0/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["HASPIN","Oxaliplatin",0.548,0.00461,-0.329,0.213,-2.74,0.00623,7.43E-3,0.43,"+/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["PAXX","RGFP966",-0.56,3.62E-3,0.346,0.189,2.84,0.0045,0.00565,0.43,"-/0","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["TMEM30A","Selinexor",-0.534,0.00595,0.277,0.299,2.52,0.0118,0.0126,0.43,"-/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["ZMAT5","Carfilzomib",0.189,0.365,-0.643,0.00722,-2.73,0.00634,0.00699,0.43,"0/-","Proteasome inhibitor (20S subunit)","PSMB5;PSMB8;PSMB1;PSMB2;PSMB9;PSMB10","Protease.proteasome inhibitor"]
["ADD1","Pomalidomide",-7.76E-4,0.997,-0.689,3.14E-3,-2.42,0.0156,0.0157,0.431,"0/-","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["CARD19","NVP_BGT226",-0.316,0.124,0.477,0.062,2.42,0.0156,0.0157,0.431,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CG;MTOR","Kinase inhibitor"]
["NOSIP","Etoposide",0.122,0.562,-0.701,2.47E-3,-2.84,0.00456,0.00572,0.431,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["TYW3","AZD3965",0.56,0.00357,-0.307,0.248,-2.72,0.00659,0.00724,0.431,"+/0","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["USP3","Pevonedistat",0.417,0.0382,-0.467,0.0682,-2.72,6.62E-3,7.26E-3,0.431,"+/0","NAE inhibitor","NAE1","Metabolic modifier"]
["ASNSD1","A_419259",0.309,0.132,-0.48,0.0596,-2.41,0.0159,0.016,0.432,"0/0","HCK and other SRC family kinase inhibitor","SRC;LCK;LYN;HCK","Kinase inhibitor"]
["CYBC1","Paclitaxel",-0.37,0.069,0.523,0.0376,2.77,0.00563,0.00698,0.432,"0/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["IKZF5","A_1155463",-0.709,{"v":7.22e-05,"d":"7.22E-05"},0.115,0.671,2.86,0.0042,0.00509,0.432,"-/0","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2","Apoptotic modulator"]
["RABGAP1L","Idelalisib",-0.193,0.357,0.688,0.00321,2.97,2.96E-3,0.00393,0.432,"0/+","PI3K inhibitor, p110-selective","PIK3CD","Kinase inhibitor"]
["TRAPPC4","Thioguanine",-0.533,0.00605,0.339,0.199,2.71,0.00675,0.00739,0.432,"-/0","Antimetabolite, Purine analog","DNMT1","Conv.Chemo"]
["UBR5","Decitabine",0.54,0.00529,-0.328,0.215,-2.7,0.00687,0.00748,0.432,"+/0","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["AUP1","Exemestane",-0.534,5.96E-3,0.24,0.371,2.4,0.0163,0.0164,0.433,"-/0","Aromatase inhibitor","CYP19A1","Hormone therapy"]
["CKS1B","Danusertib",0.454,0.0227,-0.444,0.085,-2.76,0.00573,0.0071,0.433,"+/0","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["GLRX3","Raltitrexed",0.568,0.00304,-0.297,0.264,-2.72,0.00653,0.00773,0.433,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["NAP1L5","UNC0638",0.438,0.0287,-0.478,0.0609,-2.83,0.00465,0.00583,0.433,"+/0","G9a, GLP inhibitor","EHMT2","Differentiating.epigenetic modifier"]
["ACSF3","GSK_461364",-0.617,0.00102,0.118,0.662,2.4,0.0164,0.0165,0.434,"-/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["APAF1","Cerdulatinib",-0.215,0.302,0.551,0.0268,2.4,0.0165,0.0166,0.434,"0/+","JAK, SYK inhibitor","JAK1;JAK2;JAK3;TYK2;SYK","Kinase inhibitor"]
["ACP2","Finasteride",-0.435,0.0296,0.355,0.177,2.39,0.0167,0.0167,0.434,"-/0","type II 5-alpha reductase inhibitor","SRD5A2","Hormone therapy"]
["HNRNPC","GSK269962",0.469,0.0181,-0.414,0.111,-2.71,0.0067,0.00789,0.434,"+/0","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["MAP4K1","Clofarabine",-0.399,0.0479,0.518,0.0397,2.85,0.00437,0.00525,0.434,"-/+","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["POLR3E","Raltitrexed",0.517,0.00813,-0.432,0.0944,-2.96,0.00309,0.00409,0.434,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["STARD13","Vinblastine",-0.577,0.00255,0.213,0.428,2.5,0.0125,0.0132,0.434,"-/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["BAG5","Sunitinib",-0.415,0.039,0.375,0.152,2.39,0.0168,0.0169,0.435,"-/0","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["COPS3","Rigosertib",-0.527,0.00681,0.361,0.17,2.75,0.00589,7.28E-3,0.435,"-/0","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["HIC1","Erlotinib",-0.148,0.481,0.663,0.00514,2.71,0.00681,0.00801,0.435,"0/+","EGFR inhibitor","EGFR","Kinase inhibitor"]
["SSB","GSK650394",0.0923,0.661,-0.652,0.00617,-2.49,0.0127,0.0134,0.435,"0/-","SGK1 and 2 inhibitor","SGK1","Kinase inhibitor"]
["ACOT2","Foretinib",-0.36,0.0774,0.429,0.0969,2.39,0.0169,0.017,0.436,"0/0","MET, VEGFR2 inhibitor","MET;KDR","Kinase inhibitor"]
["CENPK","ABT_751",0.445,0.0258,-0.448,0.0815,-2.75,0.006,0.00741,0.436,"+/0","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["DCAF15","PIM_447",0.27,0.192,-0.594,0.0154,-2.74,0.00609,0.00751,0.436,"0/-","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["CHAC2","Mitomycin_C",0.243,0.243,-0.61,0.0121,-2.74,0.00624,0.00765,0.436,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["EXOC5","Milciclib",-0.615,1.06E-3,0.225,0.402,2.7,0.00684,0.00805,0.436,"-/0","CDK2 inhibitor","CDK2;CDK4;CDK5;CDK7;NTRK1","Kinase inhibitor"]
["NKTR","Doxorubicin",0.583,0.00221,-0.305,0.25,-2.81,0.00498,0.00618,0.436,"+/0","Topoisomerase II inhibitor","TOP2A;NOLC1","Conv.Chemo"]
["TTC4","Raltitrexed",0.695,0.000114,-0.0835,0.759,-2.69,0.00709,0.00772,0.436,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["VPS16","Tozasertib",-0.506,0.00985,0.364,0.166,2.68,0.00729,0.0079,0.436,"-/0","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["GTPBP2","Selinexor",0.135,0.52,-0.669,0.00456,-2.7,0.00687,8.09E-3,0.437,"0/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["ETV6","Navitoclax",0.43,0.0317,-0.45,0.0804,-2.7,0.00691,0.00813,0.437,"+/0","Bcl-2,Bcl-XL inhibitor","BCL2;BCL2L2;BAD;BCL2L1;MCL1","Apoptotic modulator"]
["PITPNC1","Glesatinib",-0.181,0.386,0.663,5.11E-3,2.81,0.00501,0.00622,0.437,"0/+","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["PPP6R1","OSU_03012",-0.391,0.053,0.548,0.028,2.94,0.00327,0.00431,0.437,"0/+","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["TENT2","Belinostat",-0.476,0.0163,0.338,0.2,2.48,0.013,0.0137,0.437,"-/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["CBX3","Pomalidomide",-0.06,0.776,0.649,0.00656,2.38,0.0173,0.0173,0.438,"0/+","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["CNBP","Docetaxel",0.315,0.125,-0.555,0.0256,-2.72,0.00648,0.00791,0.438,"0/-","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["HECW1","Panobinostat",0.553,0.00414,-0.309,0.245,-2.69,0.00709,0.00834,0.438,"+/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["POLR3D","Temsirolimus",0.17,0.418,-0.694,0.00284,-2.94,3.31E-3,0.00434,0.438,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SLC43A2","Salinomycin",0.372,0.0668,-0.443,0.0855,-2.48,0.0131,0.0139,0.438,"0/0","Ionophore","ABCB1","Other"]
["ALG2","Duvelisib",-0.155,0.461,0.589,0.0164,2.38,0.0175,0.0175,0.439,"0/+","PI3K inhibitor","PIK3CD","Kinase inhibitor"]
["C16orf91","Bexarotene",-0.203,0.329,0.554,0.0261,2.37,0.0177,0.0177,0.439,"0/+","Antineoplastic agent, retinoid specifically selective for retinoid X receptors","RXRA;RXRB","Differentiating.epigenetic modifier"]
["KMO","Givinostat",0.511,0.0091,-0.403,0.121,-2.83,0.0046,0.00551,0.439,"+/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC10","Differentiating.epigenetic modifier"]
["PPP1R14B","Losmapimod",0.157,0.453,-0.7,0.00255,-2.93,0.00337,0.0044,0.439,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["TSEN54","A_1210477",-0.375,0.065,0.492,0.0528,2.67,0.00767,0.00829,0.439,"0/0","MCL-1 inhibitor","MCL1","Apoptotic modulator"]
["TPX2","Danusertib",0.474,0.0166,-0.394,0.131,-2.67,0.0077,0.00833,0.439,"+/0","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["ZNF711","Acitretin",0.409,0.0422,-0.458,0.0746,-2.66,0.00791,0.00849,0.439,"+/0","Retinoic acid receptor agonist","RARA;RARB;RXRA;RXRB;RXRG","Differentiating.epigenetic modifier"]
["CCNE1","Midostaurin",-0.531,6.3E-3,0.344,0.192,2.72,6.6E-3,0.00805,0.44,"-/0","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["DROSHA","Cisplatin",0.363,0.0745,-0.514,0.0414,-2.71,0.00666,0.00812,0.44,"0/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["JPT2","ABT_751",0.609,1.23E-3,-0.277,0.3,-2.83,0.0046,0.00552,0.44,"+/0","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["TMA16","RGFP966",0.453,0.023,-0.359,0.172,-2.47,0.0135,0.0142,0.44,"+/0","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["DIPK1A","Sepantronium_bromide",0.31,0.131,-0.554,0.0259,-2.7,0.00689,0.00834,0.441,"0/-","Survivin inhibitor","BIRC5","Apoptotic modulator"]
["FZD2","Tacedinaline",-0.478,0.0157,0.395,0.13,2.68,0.00735,0.00861,0.441,"-/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["ZNF606","Merestinib",-0.674,0.000219,0.108,0.691,2.65,0.00806,0.00866,0.441,"-/0","MET inhibitor","MET","Kinase inhibitor"]
["CAMSAP3","Omacetaxine",-0.298,0.148,0.477,0.0619,2.36,0.0182,0.0182,0.442,"0/0","Protein synthesis inhib (80 S ribosome)","RPL3","Conv.Chemo"]
["C4orf3","Tozasertib",-0.463,0.0199,0.312,0.239,2.35,0.0186,0.0185,0.442,"-/0","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["CHST11","GSK269962",-0.36,0.0769,0.513,0.0422,2.7,0.00698,0.00845,0.442,"0/+","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["PRKAR2B","Bryostatin_1",-0.536,0.0058,0.403,0.122,2.93,0.0034,4.45E-3,0.442,"-/0","PKC activator","PRKCE;PRKCA;PRKCE;PRKD1;CASP8","Kinase inhibitor"]
["SNX33","Oprozomib",-0.156,0.458,0.607,0.0126,2.46,0.0138,0.0145,0.442,"0/+","proteasome (20 S) inhibitor","PSMB5;PSMB8","Protease.proteasome inhibitor"]
["USP12","Erastin",-0.232,0.265,0.597,0.0147,2.64,8.26E-3,0.00884,0.442,"0/+","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["ZNF813","Topotecan",-0.138,0.511,0.654,5.94E-3,2.64,0.0084,0.009,0.442,"0/+","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["DNAJC18","Glesatinib",0.307,0.136,-0.555,0.0255,-2.7,0.00703,0.00854,0.443,"0/-","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["ELAC2","Decitabine",0.285,0.168,-0.567,0.022,-2.67,0.00747,0.00875,0.443,"0/-","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["NCK1","Pemetrexed",-0.597,0.00163,0.279,0.295,2.79,0.00532,0.00657,0.443,"-/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["PPP1R12C","Prexasertib",-0.571,0.00285,0.354,0.178,2.92,0.00355,0.00461,0.443,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["STK4","Raltitrexed",-0.385,0.057,0.424,0.102,2.46,0.0141,0.0148,0.443,"0/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["C1orf35","Bleomycin",-0.0883,0.675,-0.722,0.0016,-2.35,0.0187,0.0186,0.444,"0/-","Glycopeptide antibiotic, causes DNA breaks","DNA","Conv.Chemo"]
["CABLES1","8_amino_adenosine",-0.219,0.294,0.537,0.0321,2.35,0.0188,0.0188,0.444,"0/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["CD2","Fostamatinib",0.108,0.608,-0.682,3.63E-3,-2.69,0.00717,0.00868,0.444,"0/-","SYK inhibitor","SYK","Kinase inhibitor"]
["DNAJC7","Rigosertib",0.574,0.0027,-0.278,0.298,-2.68,0.0073,0.00883,0.444,"+/0","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["MRFAP1","Uprosertib",0.573,0.00275,-0.323,0.223,-2.82,0.00478,0.00572,0.444,"+/0","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["ITGB5","Gedatolisib",-0.0985,0.64,0.707,0.00218,2.8,0.00507,0.00603,0.444,"0/+","PI3K, mTOR inhibitor","PIK3CA;PIK3CG;MTOR","Kinase inhibitor"]
["NELFCD","Vinflunine",-0.423,0.0351,0.48,0.0602,2.78,0.00537,0.00663,0.444,"-/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["SCAP","Mitomycin_C",0.12,0.567,-0.714,0.00188,-2.91,3.65E-3,0.00474,0.444,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["SKIV2L","Litronesib",0.12,0.567,0.753,0.00077,2.45,0.0142,0.0149,0.444,"0/+","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["AKR1B1","Glasdegib",0.499,0.0112,-0.266,0.319,-2.34,0.0191,0.019,0.445,"+/0","Smo inhibitor","SMO","Hedgehog inhibitor"]
["BTG3","Mitoxantrone",0.305,0.138,-0.465,0.0696,-2.34,0.0192,0.0191,0.445,"0/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["ETV3","Acalabrutinib",0.467,0.0187,-0.402,0.123,-2.66,0.00776,0.00906,0.445,"+/0","BTK inhibitor","BTK","Kinase inhibitor"]
["GLTP","8_chloro_adenosine",-0.554,0.00403,0.295,0.268,2.65,0.00795,0.00923,0.445,"-/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["JRKL","Birinapant",0.258,0.213,-0.612,0.0118,-2.79,0.00527,0.00625,0.445,"0/-","IAPs, SMAC mimetic","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["TMED9","Sirolimus",-0.432,0.0311,0.376,0.152,2.45,0.0143,0.015,0.445,"-/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SMU1","Vactosertib_TEW_7197",0.38,0.0607,-0.427,0.0995,-2.45,0.0144,0.0151,0.445,"0/0","TGF receptor ALK4, ALK5 inhibitor","TGFBR1;ACVR1B","Kinase inhibitor"]
["UTP25","Gandotinib",0.175,0.402,-0.63,0.00896,-2.62,0.00869,0.00926,0.445,"0/-","JAK2 inhibitor","JAK2;JAK1;FLT3;FLT4;FGFR2;TYK2;NTRK2;FGFR3;KDR;ALK","Kinase inhibitor"]
["CCDC28A","Exemestane",0.485,0.014,-0.281,0.292,-2.34,0.0194,0.0193,0.446,"+/0","Aromatase inhibitor","CYP19A1","Hormone therapy"]
["NACA","IOX_1",0.382,0.0592,-0.513,0.0422,-2.77,0.00558,0.00685,0.446,"0/-","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["RAB5B","AZD3965",-0.35,0.086,0.571,0.021,2.9,0.00374,0.00482,0.446,"0/+","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["TRAIP","Onalespib",0.543,0.00505,-0.298,0.263,-2.62,0.0089,0.00949,0.446,"+/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["CCDC124","Cladribine",0.144,0.492,-0.586,0.0171,-2.33,0.0196,0.0195,0.447,"0/-","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["C18orf25","Ixazomib",-0.262,0.205,0.498,0.0495,2.33,0.0197,0.0196,0.447,"0/+","20S proteasome inhibitor","PSMB5","Protease.proteasome inhibitor"]
["C4orf33","Palomid_529",-0.236,0.256,0.519,0.0396,2.33,0.0198,0.0197,0.447,"0/+","AKT, MTOR, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3;MTOR","Kinase inhibitor"]
["FHOD1","8_amino_adenosine",0.0304,0.885,0.742,0.000987,2.65,0.00815,0.00945,0.447,"0/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["RAD54B","Altiratinib",0.164,0.432,-0.69,0.00311,-2.9,0.00377,0.00486,0.447,"0/-","MET, Tie-2 inhibitor","MET;NTRK1;NTRK3;NTRK2;TEK;FLT3;KIT;KDR","Kinase inhibitor"]
["TMIGD2","VS_4718",0.282,0.172,-0.509,0.0438,-2.43,0.0149,0.0156,0.447,"0/-","FAK inhibitor","PTK2","Kinase inhibitor"]
["ATG10","Alisertib",0.507,0.00964,-0.25,0.35,-2.33,0.0199,0.0197,0.448,"+/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["CHRAC1","WEHI_539",-0.331,0.107,0.529,0.035,2.67,0.00769,0.00923,0.448,"0/+","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["H6PD","Trifluridine",-0.371,0.068,0.49,0.0543,2.64,0.00819,0.0095,0.448,"0/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["IFNAR1","Volasertib",-0.408,0.0432,0.492,0.0528,2.78,0.00548,0.00648,0.448,"-/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["PPP1R37","BIIB021",-0.582,0.00227,0.331,0.21,2.89,0.0039,0.005,0.448,"-/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["VAV1","Vinorelbine",-0.323,0.115,0.521,0.0385,2.61,0.00908,0.00965,0.448,"0/+","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["ATXN7L3B","Alisertib",0.365,0.0729,-0.405,0.119,-2.32,0.0202,0.02,0.449,"0/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["GTF2E2","Cytarabine.Idarubicin",0.548,0.00458,-0.299,0.26,-2.64,0.00827,9.58E-3,0.449,"+/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["L2HGDH","Entinostat",-0.594,0.00176,0.28,0.294,2.77,0.00552,0.00653,0.449,"-/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["PRCP","Litronesib",-0.239,0.251,0.644,7.11E-3,2.88,3.96E-3,0.00506,0.449,"0/+","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["TRIM38","Docetaxel",-0.336,0.1,0.508,0.0444,2.6,0.00926,0.00984,0.449,"0/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["ARMC6","PF_03758309",0.0637,0.762,-0.634,0.00839,-2.32,0.0204,0.0202,0.45,"0/-","PAK4 inhibitor","PAK4","Kinase inhibitor"]
["PLPP1","Raltitrexed",-0.379,0.0619,0.511,0.0431,2.75,0.00593,0.00723,0.45,"0/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["PDPK1","Pevonedistat",-0.405,0.0448,0.487,0.0558,2.75,0.00601,0.00734,0.45,"-/0","NAE inhibitor","NAE1","Metabolic modifier"]
["SLU7","Pomalidomide",-0.265,0.201,0.521,0.0384,2.43,0.0152,0.0159,0.45,"0/+","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["ZBTB1","Cladribine",-0.364,0.0737,0.483,0.0582,2.6,0.00944,0.01,0.45,"0/0","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["FH","Tubastatin_A",0.487,0.0136,-0.368,0.161,-2.62,0.00867,0.00998,0.451,"+/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["PDP2","Dasatinib",0.257,0.215,-0.601,0.0138,-2.74,0.00619,0.00753,0.451,"0/-","ABL, Src, Kit, EphR Inhibitor","ABL1","Kinase inhibitor"]
["RAD17","Abexinostat",-0.229,0.271,0.649,0.0065,2.88,0.00399,0.0051,0.451,"0/+","HDAC1 selective inhibitor","HDAC1","Differentiating.epigenetic modifier"]
["TCF7","Gandotinib",0.423,0.0353,-0.376,0.151,-2.42,0.0155,0.0162,0.451,"+/0","JAK2 inhibitor","JAK2;JAK1;FLT3;FLT4;FGFR2;TYK2;NTRK2;FGFR3;KDR;ALK","Kinase inhibitor"]
["ANAPC13","Docetaxel",0.0668,0.751,-0.63,0.00885,-2.31,0.0207,0.0206,0.452,"0/-","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["DDX21","Daporinad",0.545,0.00487,-0.308,0.246,-2.66,0.00793,0.00951,0.452,"+/0","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["GNA11","Gandotinib",-0.375,0.065,0.48,0.06,2.62,0.00878,0.0101,0.452,"0/0","JAK2 inhibitor","JAK2;JAK1;FLT3;FLT4;FGFR2;TYK2;NTRK2;FGFR3;KDR;ALK","Kinase inhibitor"]
["LYSMD1","BAY_87_2243",0.558,0.00373,-0.324,0.221,-2.76,0.00573,0.00676,0.452,"+/0","HIF1alpha inhibitor","HIF1A","Differentiating.epigenetic modifier"]
["PURA","CC_115",-0.463,0.0196,0.465,0.0692,2.88,0.00403,0.00515,0.452,"-/0","mTOR, DNA-PK inhibitor","MTOR;PIK3CA;PRKDC","Kinase inhibitor"]
["SEC22B","Lifirafenib_BGB_283",-0.558,0.00378,0.357,0.175,2.87,0.00417,0.00531,0.452,"-/0","Raf inhibitor","RAF1;BRAF;EGFR","Kinase inhibitor"]
["PSMD11","Hydroxyurea",0.594,0.00176,-0.305,0.251,-2.85,0.00432,5.45E-3,0.452,"+/0","Antineoplastic agent","RRM1","Conv.Chemo"]
["SNRNP27","Masitinib",0.116,0.581,-0.622,0.0101,-2.41,0.0157,0.0164,0.452,"0/-","KIT inhibitor","KIT","Kinase inhibitor"]
["DENND5B","Idarubicin",0.41,0.0416,-0.455,0.0766,-2.65,0.00805,0.00965,0.453,"+/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["CS","PS_1145",-0.368,0.0706,0.494,0.052,2.65,0.00808,0.00967,0.453,"0/0","IKK-2 inhibitor","IKBKB","Kinase inhibitor"]
["POLR3E","Temsirolimus",0.152,0.469,-0.688,0.00322,-2.85,0.00438,0.00552,0.453,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["PSME3IP1","Niraparib",0.256,0.217,-0.624,9.75E-3,-2.84,0.00451,0.00566,0.453,"0/-","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["SRP14","Nintedanib",-0.363,0.0743,0.432,0.0943,2.41,0.0159,0.0166,0.453,"0/0","VEGFR, PDGFR, FGFR inhibitor","FGFR1;FGFR2;FLT1;FLT4;KDR;PDGFRA;PDGFRB","Kinase inhibitor"]
["TNIK","Indibulin",0.442,0.0269,-0.352,0.181,-2.41,0.0161,0.0167,0.453,"+/0","Mitoric inhibitor, Microtubule depolymerizer","TUBB","Conv.Chemo"]
["B2M","PF_00477736",-0.282,0.172,0.475,0.063,2.31,0.0211,0.021,0.454,"0/0","CHEK1 inhibitor","CHEK1;KDR;FLT3;YES1;CHEK2","Kinase inhibitor"]
["C5orf22","Daunorubicin",0.182,0.385,-0.552,0.0265,-2.3,0.0213,0.0211,0.454,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["C16orf87","GSK269962",0.54,0.00533,-0.198,0.463,-2.3,0.0215,0.0213,0.454,"+/0","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["CSPP1","AZD1775",0.574,0.00272,-0.265,0.321,-2.64,0.00822,0.00983,0.454,"+/0","Wee1 inhibitor","WEE1","Kinase inhibitor"]
["HEXA","Trifluridine",-0.648,0.000461,0.14,0.604,2.61,0.00904,0.0104,0.454,"-/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["RSL24D1","Deferoxamine",0.381,0.0604,-0.531,0.0345,-2.84,0.00457,0.00572,0.454,"0/-","Iron chelator","APP","Other"]
["PRPF38A","NMS_873",0.276,0.182,-0.608,0.0124,-2.83,0.00468,0.00586,0.454,"0/-","p97, VCP inhibitor","VCP","Other"]
["USP6NL","Rociletinib",-0.4,0.0473,0.446,0.0834,2.58,0.00978,0.0104,0.454,"-/0","EGFR(L858R, T790M) inhibitor","EGFR","Kinase inhibitor"]
["BUB1","Flutamide",-0.0814,0.699,0.618,0.0107,2.3,0.0216,0.0213,0.455,"0/+","Nonsteroidal antiandrogen","AR;AHR;NR1I2","Hormone therapy"]
["CLK4","Amsacrine",-0.477,0.016,0.382,0.144,2.63,8.43E-3,0.0101,0.455,"-/0","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["EIF5B","Tirabrutinib",0.105,0.619,-0.668,0.00467,-2.61,9.11E-3,0.0105,0.455,"0/-","BTK inhibitor","BTK","Kinase inhibitor"]
["ITSN1","Tacedinaline",-0.331,0.107,0.548,0.0279,2.74,6.11E-3,0.00715,0.455,"0/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["SLC27A3","JQ1",-0.352,0.0848,0.441,0.0876,2.4,0.0163,0.017,0.455,"0/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["C19orf53","Azacitidine",0.199,0.341,-0.537,0.0319,-2.29,0.022,0.0217,0.456,"0/-","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["ADNP2","Cerdulatinib",0.199,0.34,-0.537,0.0321,-2.29,0.022,0.0218,0.456,"0/-","JAK, SYK inhibitor","JAK1;JAK2;JAK3;TYK2;SYK","Kinase inhibitor"]
["LRIF1","TAK_901",0.231,0.266,-0.619,0.0106,-2.74,0.00615,0.00719,0.456,"0/-","Aurora, Src family, JAK3, RTK inhibitor","AURKA;AURKB;JAK3;SRC;CLK2;FGR;LRRK2;YES1;LCK;FYN;ABL1;AXL;ABL2;HCK;RET;FRK;NTRK1;FGFR2","Kinase inhibitor"]
["STK33","Triapine",0.326,0.112,-0.463,0.071,-2.4,0.0164,0.0171,0.456,"0/0","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["ZC3H3","TAK_530",0.034,0.872,0.733,1.24E-3,2.57,0.01,0.0106,0.456,"0/+","Pan-HER inhibitor","EGFR;ERBB2;ERBB3","Kinase inhibitor"]
["BRIP1","AZD_8186",0.261,0.207,-0.487,0.0558,-2.29,0.0223,0.022,0.457,"0/0","PI3K beta inhibitor","PIK3CG","Kinase inhibitor"]
["FAM111B","Tasquinimod",0.294,0.153,-0.542,0.0301,-2.6,0.00927,0.0106,0.457,"0/-","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["HENMT1","GSK2656157",-0.291,0.159,0.544,0.0293,2.6,0.00936,0.0107,0.457,"0/+","PERK inhibitor","EIF2AK3","Kinase inhibitor"]
["KIF20B","Raltitrexed",0.679,0.000187,-0.127,0.64,-2.73,0.00632,0.00741,0.457,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["TMEM126B","Midostaurin",0.155,0.46,-0.593,0.0154,-2.4,0.0165,0.0172,0.457,"0/-","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["TATDN3","Belinostat",0.64,0.000568,-0.0798,0.769,-2.4,0.0166,0.0173,0.457,"+/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["APPBP2","Cisplatin",0.153,0.467,-0.568,0.0218,-2.28,0.0226,0.0223,0.458,"0/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["ABCF2","E7820",0.354,0.0822,-0.402,0.123,-2.28,0.0228,0.0226,0.458,"0/0","Integrin alpha2 expression inhibitor","ITGA2","Other"]
["BRD9","Carboplatin",0.373,0.0666,-0.384,0.143,-2.27,0.0229,0.0226,0.458,"0/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["CFAP20","Lovastatin",0.368,0.0706,-0.486,0.0563,-2.62,0.0088,0.0104,0.458,"0/0","HMG-CoA reductase inhibitor","HMGCR","Metabolic modifier"]
["LAIR1","Canertinib",-0.266,0.199,0.592,0.0156,2.73,0.00641,0.0075,0.458,"0/+","Pan-HER inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["IGF2BP3","Bortezomib",0.283,0.171,-0.579,0.0187,-2.72,0.0065,0.00758,0.458,"0/-","Proteasome inhibitor (26S subunit)","PSMB5;PSMB1","Protease.proteasome inhibitor"]
["STK25","ODM_201",-0.671,0.000238,0.0236,0.931,2.39,0.0167,0.0174,0.458,"-/0","AR antagonist","AR","Hormone therapy"]
["CSTB","Tozasertib",-0.634,0.000668,0.165,0.542,2.61,0.00896,0.0106,0.459,"-/0","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["CCT6A","Spebrutinib",0.41,0.0418,-0.444,0.0846,-2.61,0.00902,0.0107,0.459,"+/0","BTK inhibitor","BTK","Kinase inhibitor"]
["LIMS2","Salinomycin",0.399,0.0479,-0.483,0.0581,-2.72,6.62E-3,0.00771,0.459,"+/0","Ionophore","ABCB1","Other"]
["NARF","Sirolimus",0.506,0.00989,-0.37,0.159,-2.7,0.0069,8.26E-3,0.459,"+/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SEMA4A","Idarubicin",-0.211,0.311,0.647,6.79E-3,2.81,0.00492,0.00612,0.459,"0/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["TRIP6","Uprosertib",0.382,0.0595,-0.458,0.0743,-2.57,0.0103,0.0109,0.459,"0/0","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["AMN1","Ralimetinib",0.0964,0.647,-0.602,0.0137,-2.26,0.0235,0.0232,0.46,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["DDX58","Daporinad",0.36,0.0768,-0.488,0.0553,-2.6,0.00925,0.0109,0.46,"0/0","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["MAN2A2","Mubritinib",-0.605,0.00137,0.242,0.366,2.71,0.00675,0.00785,0.46,"-/0","HER2 inhibitor","ERBB2","Kinase inhibitor"]
["TIMM22","ML390",-0.393,0.052,0.397,0.128,2.39,0.017,0.0177,0.46,"0/0","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["SQLE","Belinostat",0.268,0.195,-0.508,0.0447,-2.38,0.0171,0.0178,0.46,"0/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["WIPI1","Glesatinib",-0.218,0.295,0.588,0.0165,2.56,0.0104,0.0109,0.46,"0/+","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["ATXN7L3B","Pazopanib",0.416,0.0386,-0.335,0.204,-2.26,0.0237,0.0233,0.461,"+/0","VEGFR inhibitor","FLT1;KDR;FLT4;KIT;PDGFRA;PDGFRB;CSF1R;FGFR3;ITK","Kinase inhibitor"]
["CASP10","Dovitinib",-0.367,0.0713,0.385,0.141,2.26,0.0238,0.0234,0.461,"0/0","FGFR inhibitor","FGFR1;FGFR3;KIT;FLT3;FLT4","Kinase inhibitor"]
["AKR1A1","PFI_1",-0.182,0.384,0.541,0.0305,2.26,0.0241,0.0236,0.461,"0/+","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["HSP90AB1","Etoposide",0.47,0.0177,-0.376,0.151,-2.59,0.00962,0.011,0.461,"+/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["SACM1L","Exemestane",0.256,0.217,-0.617,0.0109,-2.81,0.00503,0.00625,0.461,"0/-","Aromatase inhibitor","CYP19A1","Hormone therapy"]
["PPP6R3","Ixazomib",0.434,0.0304,-0.473,0.0645,-2.8,0.00519,0.00642,0.461,"+/0","20S proteasome inhibitor","PSMB5","Protease.proteasome inhibitor"]
["ACTR8","PF_04708671",-0.134,0.523,0.574,0.02,2.25,0.0241,0.0237,0.462,"0/+","p70S6K inhibitor","RPS6KB1","Kinase inhibitor"]
["ABHD17B","PF_03758309",-0.0884,0.674,0.604,0.0131,2.25,0.0242,0.0238,0.462,"0/+","PAK4 inhibitor","PAK4","Kinase inhibitor"]
["FGG","Encorafenib",-0.423,0.0353,0.425,0.101,2.58,0.00974,0.0111,0.462,"-/0","BRAF(V600E) inhibitor","BRAF;RAF1","Kinase inhibitor"]
["PAK4","PF_670462",0.38,0.0612,-0.495,0.0511,-2.69,0.00705,8.43E-3,0.462,"0/0","CK1epsilon and CK1delta inhibitor","CSNK1D;CSNK1E","Kinase inhibitor"]
["SFPQ","BMS863233",0.242,0.244,-0.525,0.0368,-2.37,0.0176,0.0183,0.462,"0/-","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["WDR45","Cytarabine",-0.541,0.00523,0.282,0.29,2.56,0.0105,0.0111,0.462,"-/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["TRMT11","VS_4718",0.236,0.256,-0.573,0.0202,-2.55,0.0107,0.0113,0.462,"0/-","FAK inhibitor","PTK2","Kinase inhibitor"]
["ZBTB39","Vistusertib",0.242,0.244,-0.567,0.0219,-2.55,0.0109,0.0115,0.462,"0/-","mTOR inhibitor, ATP-competitive","MTOR","Kinase inhibitor"]
["ACSF2","Alisertib",-0.562,3.46E-3,0.151,0.576,2.25,0.0243,0.0239,0.463,"-/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["ANKRD39","GSK_690693",0.53,0.00642,-0.194,0.471,-2.25,0.0245,0.0241,0.463,"+/0","AKT, PKA, PKC inhibitor","AKT1;AKT2;AKT3;PRKCE;PRKCB;PRKCD;PRKCH;PRKCQ;PRKX;PRKG1","Kinase inhibitor"]
["DIAPH3","Selinexor",0.462,0.0202,-0.386,0.14,-2.59,0.00957,0.0112,0.463,"+/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["GTPBP4","Raltitrexed",0.631,0.000715,-0.155,0.566,-2.57,0.0101,0.0115,0.463,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["MPHOSPH8","Dexamethasone",-0.119,0.572,0.677,3.98E-3,2.69,0.00707,0.0082,0.463,"0/+","Glucocorticoid, immunomodulatory agent","NR3C1","Immunomodulatory"]
["NIPSNAP3A","Dactolisib",-0.503,0.0104,0.369,0.16,2.69,0.00721,0.00859,0.463,"-/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;ATR;RPS6KB1","Kinase inhibitor"]
["MS4A1","AZD3965",-0.602,0.00145,0.236,0.378,2.68,0.00737,8.77E-3,0.463,"-/0","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["RIMKLB","Dabrafenib",0.369,0.0694,-0.529,0.0353,-2.79,5.3E-3,0.00654,0.463,"0/-","BRAF(V600E) inhibitor","BRAF;RAF1","Kinase inhibitor"]
["PSMD11","Cabazitaxel",0.55,0.00438,-0.342,0.195,-2.79,0.00531,0.00656,0.463,"+/0","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["SYNRG","Asciminib",-0.0437,0.836,-0.702,0.00241,-2.37,0.0179,0.0185,0.463,"0/-","Allosteric ABL inhibitor, blocks myristoyl binding","ABL1","Kinase inhibitor"]
["SH3BGRL","Vistusertib",-0.4,0.0474,0.382,0.144,2.36,0.0182,0.0188,0.463,"-/0","mTOR inhibitor, ATP-competitive","MTOR","Kinase inhibitor"]
["CAMSAP3","PF_00477736",0.0533,0.8,-0.624,9.75E-3,-2.24,0.0248,0.0244,0.464,"0/-","CHEK1 inhibitor","CHEK1;KDR;FLT3;YES1;CHEK2","Kinase inhibitor"]
["EFHD2","BI_2536",-0.657,3.59E-4,0.117,0.665,2.59,0.00962,0.0113,0.464,"-/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["MICU1","MK_8745",-0.409,0.0423,0.467,0.0683,2.69,0.00717,0.00831,0.464,"-/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["PROSER3","Ridaforolimus",0.45,0.024,-0.452,0.0785,-2.78,0.00543,0.00668,0.464,"+/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SLC37A4","Tucidinostat",-0.317,0.122,0.46,0.0732,2.36,0.0182,0.0189,0.464,"0/0","HDAC1, 2, 3 and 10 inhibitor","HDAC1;HDAC2;HDAC3;HDAC10","Differentiating.epigenetic modifier"]
["ZBED4","Nelarabine",0.497,0.0116,-0.331,0.211,-2.54,0.0111,0.0117,0.464,"+/0","Antimetabolite, Nucleoside analog, DNA, RNA synth inhibitor","DNA","Conv.Chemo"]
["WDR24","Rocilinostat",-0.0218,0.917,0.699,0.00258,2.54,0.0112,0.0118,0.464,"0/+","HDAC6 selective inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["ANKRD46","AZD7762",0.385,0.0571,-0.36,0.17,-2.24,0.0251,0.0246,0.465,"0/0","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["AUH","BMS863233",-0.342,0.0943,0.402,0.123,2.24,0.0253,0.0249,0.465,"0/0","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["DHRS13","Tozasertib",-0.469,0.0181,0.376,0.151,2.58,0.00981,0.0115,0.465,"-/0","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["HAUS6","AZD_6482",0.432,0.0309,-0.41,0.115,-2.57,0.0102,0.0116,0.465,"+/0","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["GNL2","Daporinad",0.576,0.00258,-0.235,0.382,-2.56,0.0105,0.0119,0.465,"+/0","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["ITGB2","Cladribine",-0.344,0.0923,0.523,0.0377,2.68,7.28E-3,8.43E-3,0.465,"0/+","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["MUL1","Brigatinib",-0.0287,0.892,-0.744,0.000943,-2.66,0.00775,0.00916,0.465,"0/-","ALK inhibitor, including gatekeeper mutant ALK","ALK;ROS1;IGF1R;EGFR;INSR;ABL1;FLT3;MET;ERBB2;ERBB4","Kinase inhibitor"]
["OMA1","BMS863233",0.341,0.0948,-0.517,0.0401,-2.65,0.00795,0.00939,0.465,"0/-","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["PACS1","PCI_34051",-0.331,0.106,0.525,0.0367,2.65,0.008,0.00944,0.465,"0/+","HDAC8 inhibitor","HDAC8","Differentiating.epigenetic modifier"]
["TEFM","Amuvatinib",-0.314,0.127,0.462,0.0716,2.36,0.0185,0.0191,0.465,"0/0","Broad TK inhibitor","KIT;PDGFRA;FLT3","Kinase inhibitor"]
["ST7","A_1210477",-0.318,0.121,0.457,0.075,2.35,0.0186,0.0193,0.465,"0/0","MCL-1 inhibitor","MCL1","Apoptotic modulator"]
["CCDC14","Tasquinimod",0.221,0.288,-0.505,0.0459,-2.23,0.0255,0.025,0.466,"0/-","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["DLST","GSK923295",-0.543,0.00505,0.286,0.283,2.58,0.00988,0.0116,0.466,"-/0","CENP-E inhibitor","CENPE","Kinesin inhibitor"]
["MALSU1","JQ1",0.473,0.0169,-0.4,0.125,-2.68,0.00736,0.00851,0.466,"+/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["NAGA","OSU_03012",-0.652,0.000413,0.144,0.595,2.64,8.26E-3,0.00971,0.466,"-/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["TMCC1","Ralimetinib",0.235,0.257,-0.524,0.0373,-2.35,0.0189,0.0195,0.466,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["TBC1D10C","AZD_1080",-0.538,0.00554,0.217,0.42,2.35,0.0189,0.0195,0.466,"-/0","GSK3 inhibitor","GSK3B;GSK3A","Kinase inhibitor"]
["ARAP2","Copanlisib",0.147,0.482,0.73,1.33E-3,2.23,0.0257,0.0252,0.467,"0/+","PI3K alpha, delta selective inhibitor","PIK3CA;PIK3CB;PIK3CG;PIK3CD","Kinase inhibitor"]
["CACNB3","PS_1145",-0.373,0.0666,0.369,0.159,2.23,0.0259,0.0254,0.467,"0/0","IKK-2 inhibitor","IKBKB","Kinase inhibitor"]
["DPYSL3","Tosedostat",-0.336,0.101,0.501,0.048,2.57,0.0101,0.0118,0.467,"0/+","Aminopeptidase inhibitor","ANPEP","Protease.proteasome inhibitor"]
["MESD","Cabozantinib",-0.396,0.0501,0.476,0.0621,2.68,0.00739,0.00854,0.467,"0/0","VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor","KDR;MET;FLT3;KIT;RET;TEK","Kinase inhibitor"]
["NCAPH","Floxuridine",0.657,0.00036,-0.133,0.625,-2.63,0.00848,0.00993,0.467,"+/0","Antimetabolite, Analog of 5-fluorouracil","TYMS","Conv.Chemo"]
["SDE2","Belinostat",0.396,0.05,-0.499,0.049,-2.77,0.00569,0.00698,0.467,"+/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["BMPR1A","Pacritinib",0.173,0.408,-0.54,0.031,-2.23,0.026,0.0255,0.468,"0/-","FLT3, JAK2 inhibitor","FLT3;JAK2;TYK2","Kinase inhibitor"]
["ABCF1","LY3023414",0.541,0.0052,-0.17,0.529,-2.22,0.0262,0.0257,0.468,"+/0","PI3K, mTOR, DNA-PK inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;PRKDC","Kinase inhibitor"]
["CCDC88B","Epirubicin",-0.0027,0.99,0.715,0.00186,2.57,0.0101,0.0119,0.468,"0/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["HMOX2","Mitomycin_C",0.0102,0.962,-0.707,0.00222,-2.55,0.0109,0.0124,0.468,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["IL17RA","Cytarabine.Idarubicin",-0.371,0.0679,0.497,0.05,2.67,0.00751,0.00866,0.468,"0/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["TADA2A","Panobinostat",-0.0709,0.736,-0.711,2E-3,-2.34,0.0192,0.0198,0.468,"0/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["SNX8","Eribulin",-0.453,0.023,0.318,0.23,2.34,0.0194,0.02,0.468,"-/0","Mitotic inhibitor, microtubule depolymerizer","TUBB1","Conv.Chemo"]
["VPS13C","Pemetrexed",-0.557,0.00383,0.249,0.352,2.52,0.0116,0.0122,0.468,"-/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["ACAT2","GSK650394",0.223,0.285,-0.501,0.0482,-2.22,0.0264,0.0259,0.469,"0/-","SGK1 and 2 inhibitor","SGK1","Kinase inhibitor"]
["CANX","8_amino_adenosine",-0.553,0.00417,0.152,0.573,2.22,0.0266,0.026,0.469,"-/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["CBX6","Sirolimus",-0.515,0.00849,0.203,0.451,2.21,0.0268,0.0262,0.469,"-/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["COA7","C646",0.226,0.278,-0.584,0.0176,-2.57,0.0103,0.012,0.469,"0/-","EP300, CREB-binding protein (CBP) inhibitor","EP300","Differentiating.epigenetic modifier"]
["GNG7","Bexarotene",0.333,0.103,-0.493,0.0521,-2.54,0.0112,0.0126,0.469,"0/0","Antineoplastic agent, retinoid specifically selective for retinoid X receptors","RXRA;RXRB","Differentiating.epigenetic modifier"]
["GTPBP1","Topotecan",0.288,0.163,-0.53,0.0349,-2.53,0.0113,0.0128,0.469,"0/-","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["ETF1","OSU_03012",0.736,{"v":2.72E-5,"d":"2.72E-05"},0.0583,0.83,-2.53,0.0115,0.0129,0.469,"+/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["PHF12","Palbociclib",-0.61,0.00121,0.207,0.442,2.63,0.00862,0.0101,0.469,"-/0","Topoisomerase I inhibitor, Camptothecin analog","CDK4;CDK6","Kinase inhibitor"]
["SERPINB12","Belinostat",-0.468,0.0182,0.298,0.262,2.33,0.0197,0.0203,0.469,"-/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["SLU7","Daunorubicin",0.52,0.00771,-0.234,0.383,-2.33,0.0198,0.0204,0.469,"+/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["ZNF232","TGR_1202",0.279,0.177,-0.532,0.0338,-2.52,0.0119,0.0124,0.469,"0/-","PI3Kdelta inhibitor","PIK3CD","Kinase inhibitor"]
["ANO6","Mitomycin_C",-0.305,0.138,0.429,0.0975,2.21,0.0271,0.0265,0.47,"0/0","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["GNA15","Clomifene",-0.28,0.175,0.534,0.0333,2.52,0.0116,0.013,0.47,"0/+","Selective estrogen receptor modulator","ESR1;SHBG","Hormone therapy"]
["GAB2","PIM_447",-0.105,0.619,0.651,6.28E-3,2.52,0.0116,0.0131,0.47,"0/+","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["GATAD1","CC_115",-0.32,0.119,0.5,0.0485,2.52,0.0118,0.0132,0.47,"0/+","mTOR, DNA-PK inhibitor","MTOR;PIK3CA;PRKDC","Kinase inhibitor"]
["PDP2","SN_38",0.448,0.0247,-0.408,0.117,-2.62,0.00886,0.0103,0.47,"+/0","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["TBCCD1","Docetaxel",0.255,0.219,-0.503,0.0469,-2.33,0.02,0.0205,0.47,"0/-","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["SLC39A14","BX_912",0.488,0.0132,-0.272,0.309,-2.32,0.0202,0.0207,0.47,"+/0","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["TUBB","Nintedanib",-0.558,0.00377,0.245,0.361,2.51,0.012,0.0125,0.47,"-/0","VEGFR, PDGFR, FGFR inhibitor","FGFR1;FGFR2;FLT1;FLT4;KDR;PDGFRA;PDGFRB","Kinase inhibitor"]
["VAC14","Cytarabine.Idarubicin",-0.609,1.24E-3,0.168,0.534,2.51,0.0122,0.0128,0.47,"-/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["ZDHHC20","Carboplatin",-0.00656,0.975,0.701,0.0025,2.5,0.0123,0.0129,0.47,"0/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["WDR75","Dovitinib",0.0912,0.665,-0.653,0.00608,-2.49,0.0127,0.0132,0.47,"0/-","FGFR inhibitor","FGFR1;FGFR3;KIT;FLT3;FLT4","Kinase inhibitor"]
["AGAP1","Tubastatin_A",0.222,0.285,-0.498,0.0498,-2.21,0.0272,0.0266,0.471,"0/-","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["ETV3","Rigosertib",0.294,0.154,-0.521,0.0385,-2.52,0.0118,0.0133,0.471,"0/-","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["KCNAB2","Litronesib",-0.426,0.0336,0.444,0.0853,2.66,0.00772,0.00887,0.471,"-/0","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["OSBPL2","Ibrutinib",-0.393,0.0522,0.462,0.0717,2.61,0.00893,0.0105,0.471,"0/0","BTK inhibitor","BTK;BLK;EGFR;FYN;LYN;LCK;BRAF;WNK1","Kinase inhibitor"]
["SPNS1","Sirolimus",-0.357,0.0797,0.412,0.113,2.32,0.0203,0.0209,0.471,"0/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ACCS","Palomid_529",-0.0873,0.678,-0.695,0.00278,-2.2,0.0276,0.0269,0.472,"0/-","AKT, MTOR, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3;MTOR","Kinase inhibitor"]
["CCDC9","Sotrastaurin",-0.0411,0.845,0.692,2.97E-3,2.55,0.0107,0.0124,0.472,"0/+","PKC inhibitor","PRKCB;PRKCQ;PRKCH;PRKCA;PRKCE;PRKCA","Kinase inhibitor"]
["GON4L","Ivosidenib",-0.13,0.534,0.633,0.00849,2.51,0.0121,0.0135,0.472,"0/+","IDH1 R132H and R132C inhibitor","IDH1","Differentiating.epigenetic modifier"]
["FHOD1","Vactosertib_TEW_7197",-0.197,0.344,0.589,0.0163,2.51,0.0122,0.0136,0.472,"0/+","TGF receptor ALK4, ALK5 inhibitor","TGFBR1;ACVR1B","Kinase inhibitor"]
["IFI30","AT9283",-0.252,0.225,0.587,0.0169,2.66,0.00787,0.00902,0.472,"0/+","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["RIF1","GSK_1070916",0.337,0.0997,-0.543,0.0298,-2.74,0.00614,0.00748,0.472,"0/-","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["POLR3D","GSK_461364",0.412,0.0409,-0.477,0.0618,-2.73,0.00624,0.00757,0.472,"+/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["SREK1","CUDC_305",-0.418,0.0374,0.349,0.185,2.32,0.0206,0.0211,0.472,"-/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["XPNPEP3","LY_2874455",0.411,0.0411,-0.407,0.118,-2.48,0.013,0.0135,0.472,"+/0","FGFR inhibitor","FGFR1;FGFR2;FGFR3","Kinase inhibitor"]
["APOBEC3F","Vorinostat",-0.23,0.268,0.49,0.054,2.2,0.0276,0.027,0.473,"0/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["BRWD1","NVP_RAF265",0.0237,0.91,-0.633,0.00855,-2.2,0.0278,0.0272,0.473,"0/-","C-Raf inhibitor, unclear MoA","RAF1;BRAF;KDR","Kinase inhibitor"]
["ASAP2","Rocilinostat",-0.0777,0.712,-0.689,0.00317,-2.19,0.0282,0.0275,0.473,"0/-","HDAC6 selective inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["COX15","Bryostatin_1",0.534,0.00597,-0.289,0.279,-2.55,0.0107,0.0125,0.473,"+/0","PKC activator","PRKCE;PRKCA;PRKCE;PRKD1;CASP8","Kinase inhibitor"]
["EXOC1","Nelarabine",-0.46,0.0208,0.361,0.169,2.5,0.0124,0.0138,0.473,"-/0","Antimetabolite, Nucleoside analog, DNA, RNA synth inhibitor","DNA","Conv.Chemo"]
["PCYT1A","AZD7762",-0.462,0.02,0.389,0.137,2.6,0.00925,0.0108,0.473,"-/0","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["THOC7","Vidofludimus",0.061,0.772,0.701,2.47E-3,2.31,0.0208,0.0213,0.473,"0/+","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["STK39","CUDC_305",-0.474,0.0168,0.285,0.284,2.31,0.0209,0.0215,0.473,"-/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["APPBP2","Rociletinib",0.0746,0.723,0.686,0.00333,2.19,0.0285,0.0278,0.474,"0/+","EGFR(L858R, T790M) inhibitor","EGFR","Kinase inhibitor"]
["ANKH","EPZ015666",0.118,0.575,0.708,2.14E-3,2.19,0.0287,0.0279,0.474,"0/+","PRMT5 inhibitor","PRMT5","Differentiating.epigenetic modifier"]
["FTH1","AZD8055",-0.327,0.11,0.488,0.0553,2.49,0.0126,0.014,0.474,"0/0","mTOR inhibitor","MTOR","Kinase inhibitor"]
["MTHFD2","Tivozanib",0.259,0.211,-0.567,0.0219,-2.6,0.00938,0.0109,0.474,"0/-","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["POGLUT1","GSK2256098",-0.486,0.0138,0.36,0.171,2.59,0.0095,0.0111,0.474,"-/0","FAK inhibitor","PTK2","Kinase inhibitor"]
["PRMT7","Rigosertib",0.623,0.000884,-0.22,0.412,-2.73,0.00641,0.00775,0.474,"+/0","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["ZEB1","Romidepsin",-0.282,0.173,0.521,0.0387,2.48,0.0133,0.0138,0.474,"0/+","HDAC inhibitor","HDAC1;HDAC2","Differentiating.epigenetic modifier"]
["ZKSCAN8","Everolimus",0.234,0.261,-0.556,0.0253,-2.47,0.0134,0.0139,0.474,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["TOX4","Onalespib",-0.55,0.00439,0.24,0.37,2.47,0.0136,0.0141,0.474,"-/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["CERK","KU_60019",0.311,0.13,-0.514,0.0415,-2.54,0.0109,0.0127,0.475,"0/-","ATM inhibitor","ATM","Kinase inhibitor"]
["DHX37","Fostamatinib",0.435,0.0299,-0.399,0.126,-2.54,0.0111,0.0129,0.475,"+/0","SYK inhibitor","SYK","Kinase inhibitor"]
["CRELD1","Cytarabine",-0.393,0.0521,0.44,0.0878,2.54,0.0111,0.0129,0.475,"0/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["FAM111A","GSK650394",0.249,0.23,-0.548,0.028,-2.49,0.0129,0.0143,0.475,"0/-","SGK1 and 2 inhibitor","SGK1","Kinase inhibitor"]
["PEX19","Tacedinaline",-0.565,0.00328,0.26,0.331,2.59,0.00964,0.0112,0.475,"-/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["POMP","Vincristine",0.301,0.143,-0.566,0.0223,-2.72,0.00649,0.00784,0.475,"0/-","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB;TUBA4A","Conv.Chemo"]
["ZNF460","Etoposide",-0.337,0.0998,0.471,0.0656,2.46,0.0138,0.0142,0.475,"0/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["ACSF2","Selumetinib",-0.168,0.423,0.533,0.0335,2.18,0.0291,0.0283,0.476,"0/+","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["CYBRD1","TAK_901",-0.432,0.0311,0.401,0.124,2.53,0.0113,0.0131,0.476,"-/0","Aurora, Src family, JAK3, RTK inhibitor","AURKA;AURKB;JAK3;SRC;CLK2;FGR;LRRK2;YES1;LCK;FYN;ABL1;AXL;ABL2;HCK;RET;FRK;NTRK1;FGFR2","Kinase inhibitor"]
["GPX1","RGFP966",-0.526,0.00689,0.277,0.299,2.48,0.013,0.0144,0.476,"-/0","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["ITM2C","Lovastatin",-0.157,0.455,0.645,0.00699,2.64,0.00823,0.00943,0.476,"0/+","HMG-CoA reductase inhibitor","HMGCR","Metabolic modifier"]
["KANK2","Tamatinib",-0.408,0.0427,0.454,0.0774,2.64,0.00831,0.00951,0.476,"-/0","SYK inhibitor","SYK","Kinase inhibitor"]
["NPHP4","KU_60019",0.347,0.0894,-0.495,0.0513,-2.59,0.00973,0.0113,0.476,"0/0","ATM inhibitor","ATM","Kinase inhibitor"]
["PIK3AP1","Cytarabine",-0.615,1.06E-3,0.184,0.496,2.58,0.00984,0.0114,0.476,"-/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["SDF2L1","Lonafarnib",0.396,0.0504,-0.486,0.0561,-2.71,0.00664,0.008,0.476,"0/0","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["SYNJ1","CC_223",-0.216,0.3,0.526,0.0363,2.3,0.0215,0.022,0.476,"0/+","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["BUD13","Cisplatin",0.0662,0.753,-0.602,0.0136,-2.18,0.0293,0.0285,0.477,"0/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["APAF1","Selinexor",-0.24,0.248,0.476,0.0625,2.18,0.0294,0.0286,0.477,"0/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["H1-3","PF_670462",-0.457,0.0217,0.357,0.174,2.48,0.0132,0.0146,0.477,"-/0","CK1epsilon and CK1delta inhibitor","CSNK1D;CSNK1E","Kinase inhibitor"]
["MORC3","Tubastatin_A",-0.351,0.0856,0.503,0.0473,2.63,0.00862,0.00982,0.477,"0/+","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["PIK3R1","Glesatinib",-0.277,0.18,0.55,0.0274,2.58,9.92E-3,0.0115,0.477,"0/+","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["SMC2","Sirolimus",0.523,0.00735,-0.22,0.413,-2.3,0.0216,0.0221,0.477,"+/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["TPMT","OSU_03012",-0.218,0.296,0.563,0.0233,2.45,0.0142,0.0146,0.477,"0/+","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["ZFP1","Acitretin",0.302,0.142,-0.497,0.0503,-2.45,0.0143,0.0147,0.477,"0/0","Retinoic acid receptor agonist","RARA;RARB;RXRA;RXRB;RXRG","Differentiating.epigenetic modifier"]
["ATAT1","Gedatolisib",0.384,0.0578,-0.341,0.196,-2.17,0.0297,0.0289,0.478,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CG;MTOR","Kinase inhibitor"]
["EDF1","Selumetinib",0.0905,0.667,-0.66,0.00543,-2.52,0.0116,0.0134,0.478,"0/-","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["MESD","Pemetrexed",-0.548,0.00453,0.293,0.27,2.62,0.00868,0.00987,0.478,"-/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["MYO5A","IOX_2",0.287,0.165,-0.54,0.0307,-2.57,0.0101,0.0117,0.478,"0/-","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["SEL1L","ABT_751",-0.665,0.000288,0.144,0.594,2.71,0.0068,0.00819,0.478,"-/0","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["SEL1L","SN_38",-0.57,0.0029,0.289,0.278,2.7,0.00689,0.00825,0.478,"-/0","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["TBCC","AZD_5363",0.274,0.186,-0.478,0.0611,-2.29,0.022,0.0226,0.478,"0/0","AKT inhibitor","AKT1;AKT2;AKT3;ROCK2","Kinase inhibitor"]
["TPM4","Sirolimus",-0.237,0.253,0.547,0.0283,2.45,0.0144,0.0149,0.478,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["TPP1","Filanesib",-0.355,0.0817,0.449,0.0809,2.44,0.0145,0.015,0.478,"0/0","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["CBL","Merestinib",-0.469,0.0181,0.247,0.357,2.17,0.0298,0.029,0.479,"-/0","MET inhibitor","MET","Kinase inhibitor"]
["CCDC14","Tubacin",0.0331,0.875,-0.62,0.0104,-2.17,0.0301,0.0293,0.479,"0/-","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["DOK2","Luminespib",-0.049,0.816,0.682,3.64E-3,2.52,0.0118,0.0136,0.479,"0/+","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["FAM13B","Vinblastine",-0.456,0.0219,0.356,0.176,2.47,0.0135,0.0149,0.479,"-/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["NR2C2AP","Methotrexate",0.0965,0.646,0.759,0.000656,2.56,0.0104,0.012,0.479,"0/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["PLEKHG1","Losmapimod",-0.0971,0.644,0.663,5.11E-3,2.56,0.0105,0.012,0.479,"0/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["VKORC1L1","Tivantinib",-0.361,0.0765,0.442,0.0862,2.44,0.0148,0.0152,0.479,"0/0","MET inhibitor","MET","Kinase inhibitor"]
["CADM4","KU_60019",0.384,0.0584,-0.339,0.199,-2.17,0.0304,0.0295,0.48,"0/0","ATM inhibitor","ATM","Kinase inhibitor"]
["EFNB2","Everolimus",0.644,0.000519,-0.115,0.671,-2.52,0.0119,0.0137,0.48,"+/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["FGFR1OP","Nelarabine",0.179,0.391,-0.593,0.0156,-2.47,0.0136,0.0151,0.48,"0/-","Antimetabolite, Nucleoside analog, DNA, RNA synth inhibitor","DNA","Conv.Chemo"]
["IKBKG","UNC0638",0.103,0.624,0.769,0.000499,2.61,0.00896,0.0102,0.48,"0/+","G9a, GLP inhibitor","EHMT2","Differentiating.epigenetic modifier"]
["PPP1R9B","WEHI_539",0.675,2.12E-4,-0.124,0.648,-2.7,0.00692,0.00833,0.48,"+/0","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["SCAF11","Palomid_529",0.502,0.0106,-0.372,0.156,-2.69,0.00706,0.00846,0.48,"+/0","AKT, MTOR, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3;MTOR","Kinase inhibitor"]
["TIMM10","GSK2656157",-0.307,0.135,0.447,0.0826,2.28,0.0225,0.023,0.48,"0/0","PERK inhibitor","EIF2AK3","Kinase inhibitor"]
["TMEM43","Raltitrexed",-0.493,0.0122,0.252,0.347,2.28,0.0226,0.0231,0.48,"-/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["SLC31A1","Imatinib",0.583,0.00221,-0.128,0.637,-2.28,0.0229,0.0234,0.48,"+/0","ABL, Kit, PDGFRB inhibitor","ABL1","Kinase inhibitor"]
["AGO2","PF_00477736",-0.103,0.625,0.574,0.02,2.16,0.0305,0.0297,0.481,"0/+","CHEK1 inhibitor","CHEK1;KDR;FLT3;YES1;CHEK2","Kinase inhibitor"]
["C1orf50","VER_155008",-0.117,0.579,0.564,0.0229,2.16,0.0307,0.0299,0.481,"0/+","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["CRMP1","GSK2830371",0.444,0.0261,-0.382,0.144,-2.51,0.0119,0.0138,0.481,"+/0","Wip1 inhibitor","PPM1D","Other"]
["CLIC4","AMG319",-0.27,0.192,0.538,0.0317,2.51,0.0121,0.0139,0.481,"0/+","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["EPG5","Erastin",-0.299,0.147,0.502,0.0477,2.46,0.014,0.0154,0.481,"0/+","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["MARK4","Imiquimod",-0.0203,0.923,0.712,1.97E-3,2.61,0.00915,0.0104,0.481,"0/+","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["NDRG2","KU_60019",0.34,0.0962,-0.493,0.0525,-2.56,0.0106,0.0122,0.481,"0/0","ATM inhibitor","ATM","Kinase inhibitor"]
["SRSF10","Raltitrexed",0.298,0.148,-0.453,0.0784,-2.27,0.023,0.0235,0.481,"0/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["TWF1","Agerafenib_CEP_32496",0.267,0.196,-0.519,0.0394,-2.43,0.0152,0.0156,0.481,"0/-","BRAF(V600E) inhibitor","BRAF;RAF1;KIT;RET;LCK;ABL1;PDGFRB;CSF1R;MET;EGFR;KDR;EPHA2","Kinase inhibitor"]
["ACP1","Fludarabine",0.247,0.233,-0.463,0.0707,-2.16,0.0311,0.0302,0.482,"0/0","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["HMMR","Cabazitaxel",0.622,0.000906,-0.13,0.632,-2.45,0.0141,0.0156,0.482,"+/0","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["HSPA4L","Fludarabine",0.116,0.582,-0.63,0.00893,-2.45,0.0143,0.0157,0.482,"0/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["KMO","A_1331852",0.327,0.111,-0.514,0.0418,-2.59,0.0095,0.0107,0.482,"0/-","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2;MCL1","Apoptotic modulator"]
["RELL1","Alisertib",-0.6,0.00153,0.243,0.364,2.69,0.00717,0.00858,0.482,"-/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["SRPRB","AZD7762",0.624,8.52E-4,-0.0622,0.819,-2.27,0.0232,0.0237,0.482,"+/0","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["SH2B3","Gemcitabine",-0.179,0.393,0.546,0.0288,2.27,0.0234,0.0239,0.482,"0/+","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["SRF","Alisertib",-0.244,0.24,0.495,0.051,2.26,0.0235,0.024,0.482,"0/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["BABAM2","Verdinexor",-0.345,0.0907,0.374,0.154,2.15,0.0314,0.0305,0.483,"0/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["CSTA","TGX_221",-0.351,0.0851,0.47,0.0662,2.51,0.0122,0.0141,0.483,"0/0","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["DDX31","Glesatinib",0.584,2.16E-3,-0.205,0.447,-2.51,0.0122,0.0141,0.483,"+/0","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["EPB41L5","SN_38",0.225,0.28,-0.555,0.0255,-2.44,0.0145,0.0159,0.483,"0/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["OS9","Glasdegib",0.514,0.00863,-0.314,0.237,-2.55,0.0107,0.0123,0.483,"+/0","Smo inhibitor","SMO","Hedgehog inhibitor"]
["RIPK3","AZD8055",0.0165,0.938,0.742,0.000997,2.68,0.00729,0.00872,0.483,"0/+","mTOR inhibitor","MTOR","Kinase inhibitor"]
["SERAC1","Losmapimod",0.191,0.361,-0.536,0.0325,-2.26,0.0237,0.0242,0.483,"0/-","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["SPATS2L","Buparlisib",-0.152,0.468,0.563,0.0233,2.26,0.0239,0.0244,0.483,"0/+","PI3K inhibitor, pan-class I","PIK3CA;PIK3CB;PIK3CG;PIK3CD;MTOR;PIK3C3","Kinase inhibitor"]
["TAP1","Vinblastine",-0.32,0.118,0.428,0.0985,2.26,0.0241,0.0245,0.483,"0/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["ZFAND1","CCT196969",0.182,0.383,-0.581,0.0184,-2.42,0.0154,0.0158,0.483,"0/-","pan-RAF, Src inhibitor","RAF1;BRAF;SRC;LCK","Kinase inhibitor"]
["APPL1","Rigosertib",-0.573,0.00275,0.0982,0.717,2.15,0.0319,0.0309,0.484,"-/0","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["ABI2","Merestinib",-0.0253,0.904,-0.65,0.0064,-2.14,0.032,0.031,0.484,"0/-","MET inhibitor","MET","Kinase inhibitor"]
["AP3M1","BMS863233",-0.354,0.0825,0.361,0.169,2.14,0.0324,0.0313,0.484,"0/0","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["CBLL1","Daunorubicin",0.21,0.315,-0.49,0.0542,-2.14,0.0324,0.0314,0.484,"0/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["CELSR2","ML390",-0.173,0.408,0.604,0.0132,2.5,0.0125,0.0144,0.484,"0/+","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["COL6A3","Imatinib",0.552,0.00419,-0.246,0.359,-2.5,0.0126,0.0145,0.484,"+/0","ABL, Kit, PDGFRB inhibitor","ABL1","Kinase inhibitor"]
["GDAP2","Raltitrexed",-0.486,0.0138,0.312,0.24,2.44,0.0147,0.0161,0.484,"-/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["GPCPD1","Foretinib",0.576,0.00256,-0.193,0.474,-2.44,0.0148,0.0163,0.484,"+/0","MET, VEGFR2 inhibitor","MET;KDR","Kinase inhibitor"]
["FBXO28","Ibrutinib",0.341,0.0958,-0.459,0.0737,-2.43,0.015,0.0165,0.484,"0/0","BTK inhibitor","BTK;BLK;EGFR;FYN;LYN;LCK;BRAF;WNK1","Kinase inhibitor"]
["GABARAPL2","Raltitrexed",-0.0379,0.857,-0.71,0.00204,-2.43,0.0151,0.0166,0.484,"0/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["PARD6B","C646",0.3,0.146,-0.523,0.0375,-2.54,0.011,0.0126,0.484,"0/-","EP300, CREB-binding protein (CBP) inhibitor","EP300","Differentiating.epigenetic modifier"]
["SEH1L","Ivosidenib",0.476,0.0162,-0.398,0.127,-2.68,0.00731,0.00874,0.484,"+/0","IDH1 R132H and R132C inhibitor","IDH1","Differentiating.epigenetic modifier"]
["SLC16A7","Gedatolisib",-0.247,0.233,0.49,0.054,2.25,0.0241,0.0246,0.484,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CG;MTOR","Kinase inhibitor"]
["THBS1","RGFP966",-0.379,0.062,0.371,0.158,2.25,0.0244,0.0248,0.484,"0/0","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["ZNF511","Onalespib",0.248,0.232,-0.532,0.0341,-2.42,0.0156,0.016,0.484,"0/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["C12orf43","Cytarabine",0.41,0.0419,-0.302,0.256,-2.13,0.0328,0.0317,0.485,"+/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["GNS","Methotrexate",-0.202,0.332,0.568,0.0218,2.43,0.0152,0.0166,0.485,"0/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["PACC1","PFI_1",0.258,0.213,-0.554,0.0261,-2.54,0.0112,0.0128,0.485,"0/-","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["NUFIP2","GSK_1070916",0.272,0.188,-0.542,0.0299,-2.54,0.0112,0.0128,0.485,"0/-","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["TBL1Y","Dexamethasone",0.412,0.0407,-0.335,0.205,-2.25,0.0246,0.0251,0.485,"+/0","Glucocorticoid, immunomodulatory agent","NR3C1","Immunomodulatory"]
["ZNF70","PS_1145",0.0676,0.748,-0.651,0.00632,-2.41,0.0158,0.0161,0.485,"0/-","IKK-2 inhibitor","IKBKB","Kinase inhibitor"]
["CALML3","Sotrastaurin",-0.312,0.129,0.4,0.125,2.13,0.0329,0.0318,0.486,"0/0","PKC inhibitor","PRKCB;PRKCQ;PRKCH;PRKCA;PRKCE;PRKCA","Kinase inhibitor"]
["ABCB6","Sepantronium_bromide",-0.402,0.0461,0.309,0.245,2.13,0.033,0.032,0.486,"-/0","Survivin inhibitor","BIRC5","Apoptotic modulator"]
["ACTB","Onalespib",0.227,0.275,-0.473,0.0644,-2.13,0.0332,0.0321,0.486,"0/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["CDH2","Valrubicin",0.348,0.0878,-0.467,0.0684,-2.49,0.0129,0.0148,0.486,"0/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["FAM107B","Luminespib",-0.152,0.469,0.601,0.0138,2.42,0.0154,0.0169,0.486,"0/+","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["HMGCL","Resminostat",-0.189,0.365,0.575,0.0199,2.42,0.0156,0.017,0.486,"0/+","HDAC1, 3, 6 inhibitor","HDAC1;HDAC3;HDAC6","Differentiating.epigenetic modifier"]
["MAX","LY_2874455",-0.39,0.054,0.453,0.0782,2.57,0.0101,0.0114,0.486,"0/0","FGFR inhibitor","FGFR1;FGFR2;FGFR3","Kinase inhibitor"]
["LRP8","Mubritinib",0.486,0.0138,-0.352,0.182,-2.57,0.0103,0.0115,0.486,"+/0","HER2 inhibitor","ERBB2","Kinase inhibitor"]
["SENP5","Tazemetostat",0.323,0.115,-0.536,0.0324,-2.67,0.00764,0.0091,0.486,"0/-","EZH2 inhibitor","EZH2","Differentiating.epigenetic modifier"]
["SMYD2","Amsacrine",0.46,0.0208,-0.28,0.294,-2.24,0.025,0.0254,0.486,"+/0","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["SUGP2","Azacitidine",-0.474,0.0168,0.261,0.328,2.24,0.0254,0.0257,0.486,"-/0","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["ACTR8","Topotecan",0.313,0.128,-0.397,0.128,-2.13,0.0335,0.0324,0.487,"0/0","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["ANKRD49","RGFP966",0.133,0.526,-0.544,0.0295,-2.12,0.0337,0.0326,0.487,"0/-","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["ACOX1","Paclitaxel",0.173,0.408,0.724,1.5E-3,2.12,0.0339,0.0327,0.487,"0/+","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["CISD1","Mubritinib",-0.178,0.395,0.596,0.0148,2.48,0.0132,0.0151,0.487,"0/+","HER2 inhibitor","ERBB2","Kinase inhibitor"]
["DTX3L","Clofarabine",-0.36,0.0773,0.454,0.0774,2.48,0.0133,0.0152,0.487,"0/0","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["ETHE1","Pevonedistat",-0.153,0.464,0.598,0.0144,2.42,0.0157,0.0172,0.487,"0/+","NAE inhibitor","NAE1","Metabolic modifier"]
["GALK2","Saracatinib",-0.433,0.0305,0.362,0.168,2.41,0.0159,0.0173,0.487,"-/0","Src, ABL inhibitor","ABL1;SRC;LCK;YES1;LYN;FYN;BLK;EGFR;KIT;EPHA2","Kinase inhibitor"]
["METTL5","Masitinib",0.116,0.582,-0.653,6.11E-3,-2.56,0.0104,0.0116,0.487,"0/-","KIT inhibitor","KIT","Kinase inhibitor"]
["PIDD1","WEHI_539",-0.395,0.051,0.436,0.0913,2.53,0.0115,0.013,0.487,"0/0","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["RAB5C","Lonafarnib",-0.343,0.0929,0.517,0.0403,2.66,0.00784,0.00933,0.487,"0/+","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["STARD5","Bleomycin",-0.366,0.0717,0.378,0.149,2.23,0.0254,0.0258,0.487,"0/0","Glycopeptide antibiotic, causes DNA breaks","DNA","Conv.Chemo"]
["TMEM63A","Pexidartinib",-0.502,0.0106,0.225,0.402,2.23,0.0256,0.0259,0.487,"-/0","KIT, CSF1R, FLT3 inhibitor","CSF1R;FLT3;KIT","Kinase inhibitor"]
["TRPM2","EPZ015666",-0.267,0.196,0.514,0.0417,2.41,0.0161,0.0164,0.487,"0/+","PRMT5 inhibitor","PRMT5","Differentiating.epigenetic modifier"]
["VAMP4","Entinostat",0.354,0.0825,-0.44,0.0885,-2.41,0.0161,0.0165,0.487,"0/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["C6orf120","Tivantinib",-0.384,0.058,0.325,0.22,2.12,0.0339,0.0328,0.488,"0/0","MET inhibitor","MET","Kinase inhibitor"]
["ABHD6","WEHI_539",0.326,0.111,-0.381,0.145,-2.12,0.0343,0.0331,0.488,"0/0","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["CDC73","AZD1775",0.337,0.099,-0.472,0.0648,-2.47,0.0135,0.0154,0.488,"0/0","Wee1 inhibitor","WEE1","Kinase inhibitor"]
["CD81","GSK2636771",-0.445,0.0257,0.365,0.164,2.46,0.0137,0.0156,0.488,"-/0","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["NIBAN1","Foretinib",-0.198,0.342,0.594,0.0153,2.53,0.0115,0.0131,0.488,"0/+","MET, VEGFR2 inhibitor","MET;KDR","Kinase inhibitor"]
["NKRF","Fluorouracil",0.356,0.0803,-0.471,0.0658,-2.53,0.0115,0.0131,0.488,"0/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","TYMS","Conv.Chemo"]
["TMEM87B","Sirolimus",-0.418,0.0378,0.322,0.224,2.23,0.026,0.0263,0.488,"-/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ZFYVE9","Tivozanib",0.253,0.222,-0.522,0.0379,-2.4,0.0166,0.0169,0.488,"0/-","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["TRIM38","Axitinib",-0.379,0.0615,0.411,0.113,2.39,0.0168,0.0171,0.488,"0/0","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["ATP2A2","Crenolanib",0.554,0.00403,-0.115,0.671,-2.12,0.0344,0.0332,0.489,"+/0","PDGFRA and PDGFRB inhibitor","PDGFRA","Kinase inhibitor"]
["CCDC174","Litronesib",0.247,0.234,-0.451,0.0792,-2.11,0.0347,0.0335,0.489,"0/0","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["CSRP1","Dactolisib",-0.258,0.213,0.535,0.0327,2.46,0.0138,0.0157,0.489,"0/+","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;ATR;RPS6KB1","Kinase inhibitor"]
["HDHD2","ODM_201",-0.161,0.443,0.591,0.016,2.4,0.0163,0.0177,0.489,"0/+","AR antagonist","AR","Hormone therapy"]
["KBTBD4","Triciribine",0.291,0.158,-0.532,0.0341,-2.55,0.0107,0.012,0.489,"0/-","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["SCARF1","Varlitinib",-0.0432,0.837,0.708,2.15E-3,2.65,8.09E-3,0.00956,0.489,"0/+","EGFR HER2 inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["TMEM65","Sepantronium_bromide",0.214,0.303,-0.508,0.0445,-2.22,0.0262,0.0265,0.489,"0/-","Survivin inhibitor","BIRC5","Apoptotic modulator"]
["SLC36A1","Ponatinib",0.0881,0.675,-0.597,0.0147,-2.22,0.0264,0.0267,0.489,"0/-","Broad TK inhibitor","ABL1;PDGFRA;KDR;FGFR1;SRC;KIT","Kinase inhibitor"]
["TSR1","Galiellalactone",0.173,0.408,-0.579,0.0187,-2.39,0.0169,0.0172,0.489,"0/-","STAT3-DNA interaction inhibitor","STAT3","Other"]
["E2F1","SCH772984",0.148,0.48,-0.611,0.0119,-2.46,0.014,0.0159,0.49,"0/-","ERK1 and 2 inhibitor","MAPK3","Kinase inhibitor"]
["CLTC","THZ2",-0.202,0.332,0.574,0.0201,2.45,0.0142,0.0161,0.49,"0/+","CDK7 inhibitor","CDK7","Kinase inhibitor"]
["HSF2","Tamatinib",0.346,0.0901,-0.445,0.084,-2.4,0.0164,0.0178,0.49,"0/0","SYK inhibitor","SYK","Kinase inhibitor"]
["MKNK1","Dovitinib",0.487,0.0136,-0.344,0.192,-2.55,0.0109,0.0122,0.49,"+/0","FGFR inhibitor","FGFR1;FGFR3;KIT;FLT3;FLT4","Kinase inhibitor"]
["PRRC2C","Lonafarnib",0.527,0.00675,-0.326,0.219,-2.64,0.00823,0.00976,0.49,"+/0","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["PSMA7","Romidepsin",-0.128,0.543,0.662,0.00525,2.64,8.26E-3,0.00978,0.49,"0/+","HDAC inhibitor","HDAC1;HDAC2","Differentiating.epigenetic modifier"]
["SOGA1","OSU_03012",0.446,0.0254,-0.287,0.28,-2.22,0.0266,0.0269,0.49,"+/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["ASXL1","AT9283",0.263,0.205,-0.437,0.0903,-2.11,0.0349,0.0338,0.491,"0/0","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["BUB1","PAC_1",0.0625,0.767,-0.588,0.0167,-2.11,0.0352,0.034,0.491,"0/-","procaspase-3 activator","CASP3","Apoptotic modulator"]
["ADIPOR1","VS_4718",-0.24,0.248,0.455,0.0763,2.1,0.0353,0.0341,0.491,"0/0","FAK inhibitor","PTK2","Kinase inhibitor"]
["CRYZL1","Valrubicin",-0.418,0.0374,0.389,0.136,2.45,0.0143,0.0163,0.491,"-/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["DOCK4","AZD7762",0.594,1.73E-3,-0.17,0.53,-2.45,0.0145,0.0164,0.491,"+/0","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["DENND3","Paclitaxel",-0.407,0.0435,0.399,0.126,2.44,0.0146,0.0165,0.491,"-/0","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["GOLGB1","Mubritinib",-0.373,0.0663,0.419,0.107,2.4,0.0166,0.018,0.491,"0/0","HER2 inhibitor","ERBB2","Kinase inhibitor"]
["INPP5D","Filanesib",-0.494,0.012,0.334,0.206,2.54,0.011,0.0122,0.491,"-/0","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["OS9","Tazemetostat",-0.28,0.176,0.531,0.0344,2.51,0.012,0.0136,0.491,"0/+","EZH2 inhibitor","EZH2","Differentiating.epigenetic modifier"]
["RPS27L","AZD1775",-0.257,0.215,0.577,0.0193,2.63,0.0085,0.01,0.491,"0/+","Wee1 inhibitor","WEE1","Kinase inhibitor"]
["ROCK2","MST_312",-0.332,0.105,0.519,0.0395,2.63,8.6E-3,0.0101,0.491,"0/+","Telomerase inhibitor","TERT","Other"]
["USP10","BMS863233",0.317,0.122,-0.466,0.0692,-2.38,0.0173,0.0176,0.491,"0/0","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["CALCOCO1","Vismodegib",-0.0566,0.788,0.59,0.0161,2.1,0.0357,0.0344,0.492,"0/+","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["ATP11B","Idelalisib",-0.334,0.102,0.368,0.16,2.1,0.0358,0.0346,0.492,"0/0","PI3K inhibitor, p110-selective","PIK3CD","Kinase inhibitor"]
["DAB2IP","AT9283",0.46,0.0207,-0.341,0.196,-2.44,0.0148,0.0167,0.492,"+/0","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["GLIPR1","Methylprednisolone",-0.219,0.294,0.546,0.0285,2.39,0.0169,0.0184,0.492,"0/+","Glucocorticoid, immunomodulatory agent","NR3C1","Immunomodulatory"]
["GTPBP4","A_1331852",-0.584,0.0022,0.164,0.543,2.38,0.0172,0.0186,0.492,"-/0","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2;MCL1","Apoptotic modulator"]
["EPB41L2","Resminostat",0.355,0.0817,-0.432,0.0947,-2.38,0.0172,0.0186,0.492,"0/0","HDAC1, 3, 6 inhibitor","HDAC1;HDAC3;HDAC6","Differentiating.epigenetic modifier"]
["PLEKHG1","Mitomycin_C",0.0445,0.833,0.727,0.00143,2.51,0.0121,0.0138,0.492,"0/+","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["NKRF","Temsirolimus",0.171,0.413,-0.606,0.0129,-2.5,0.0123,0.014,0.492,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["PSMG1","Epirubicin",0.0824,0.695,-0.684,3.49E-3,-2.63,0.00864,0.0102,0.492,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["SLF2","Sitravatinib",-0.405,0.0444,0.33,0.212,2.21,0.0271,0.0274,0.492,"-/0","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["ZC3H12D","Mivebresib",-0.458,0.0214,0.325,0.22,2.38,0.0175,0.0178,0.492,"-/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["B3GAT3","I_BET151",0.435,0.0297,-0.261,0.329,-2.1,0.036,0.0348,0.493,"+/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["C4orf46","Docetaxel",0.305,0.138,-0.395,0.13,-2.09,0.0363,0.035,0.493,"0/0","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["DMAP1","Talazoparib",0.333,0.104,-0.466,0.0689,-2.43,0.015,0.017,0.493,"0/0","PARP1 and 2 inhibitor","PARP1;PARP2","Differentiating.epigenetic modifier"]
["FASTKD3","Selumetinib",0.22,0.291,-0.543,0.0296,-2.38,0.0173,0.0188,0.493,"0/-","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["LDLRAD4","Canertinib",0.263,0.204,-0.55,0.0274,-2.54,0.0112,0.0125,0.493,"0/-","Pan-HER inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["STMN1","GSK269962",-0.00498,0.981,-0.651,6.3E-3,-2.21,0.0273,0.0276,0.493,"0/-","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["SF3B3","Sirolimus",0.331,0.106,-0.403,0.121,-2.21,0.0273,0.0276,0.493,"0/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ZNF749","Everolimus",0.233,0.263,-0.532,0.0338,-2.37,0.0176,0.0179,0.493,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["ARPP19","Flutamide",0.346,0.0902,-0.354,0.179,-2.09,0.0367,0.0353,0.494,"0/0","Nonsteroidal antiandrogen","AR;AHR;NR1I2","Hormone therapy"]
["BTBD6","BAY_87_2243",-0.393,0.0517,0.305,0.251,2.09,0.0367,0.0353,0.494,"0/0","HIF1alpha inhibitor","HIF1A","Differentiating.epigenetic modifier"]
["DCD","AZD_8186",-0.354,0.083,0.446,0.0832,2.43,0.0152,0.0172,0.494,"0/0","PI3K beta inhibitor","PIK3CG","Kinase inhibitor"]
["LGMN","Fostamatinib",0.501,0.0107,-0.323,0.222,-2.53,0.0113,0.0125,0.494,"+/0","SYK inhibitor","SYK","Kinase inhibitor"]
["PLEKHG3","ARV_825",0.154,0.462,0.773,0.000443,2.5,0.0126,0.0142,0.494,"0/+","BET-targeting PROTAC","BRD4","Differentiating.epigenetic modifier"]
["TCEAL8","PFI_1",0.0418,0.843,-0.622,0.0101,-2.2,0.0277,0.028,0.494,"0/-","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["SF3A2","SN_38",0.294,0.154,-0.435,0.0919,-2.2,0.028,0.0282,0.494,"0/0","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["ZNF827","BMS_754807",-0.0625,0.767,0.645,6.96E-3,2.37,0.0177,0.0181,0.494,"0/+","IGF1R inhibitor","IGF1R","Kinase inhibitor"]
["BLOC1S3","Danusertib",-0.547,0.0047,0.115,0.671,2.08,0.0371,0.0357,0.495,"-/0","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["ACOT13","GSK_1070916",-0.32,0.118,0.377,0.15,2.08,0.0372,0.0358,0.495,"0/0","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["EIF3D","AZD1775",0.39,0.0542,-0.394,0.131,-2.37,0.018,0.0194,0.495,"0/0","Wee1 inhibitor","WEE1","Kinase inhibitor"]
["LLPH","Temsirolimus",0.136,0.516,-0.634,0.00839,-2.53,0.0114,0.0127,0.495,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["MARS1","TGR_1202",0.142,0.497,-0.628,0.00913,-2.52,0.0117,0.0129,0.495,"0/-","PI3Kdelta inhibitor","PIK3CD","Kinase inhibitor"]
["ME1","AZD_5438",-0.1,0.634,0.653,0.00606,2.52,0.0117,0.013,0.495,"0/+","CDK1, 2, 9 inhibitor","CDK1;CDK2;CDK9","Kinase inhibitor"]
["LCP2","PCI_34051",-0.135,0.519,0.631,0.00882,2.51,0.012,0.0133,0.495,"0/+","HDAC8 inhibitor","HDAC8","Differentiating.epigenetic modifier"]
["SDC2","AT_406",0.527,0.00681,-0.318,0.23,-2.62,0.00888,0.0104,0.495,"+/0","XIAP, cIAP1, cIAP2 inhibitor","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["TENT2","Luminespib",-0.494,0.012,0.223,0.408,2.2,0.0281,0.0284,0.495,"-/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["ZNF496","BMS_911543",-0.353,0.0835,0.429,0.0971,2.37,0.018,0.0183,0.495,"0/0","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["BRMS1","PAC_1",-0.224,0.281,0.462,0.0715,2.08,0.0374,0.036,0.496,"0/0","procaspase-3 activator","CASP3","Apoptotic modulator"]
["CHAF1B","PCI_34051",0.417,0.0379,-0.382,0.144,-2.42,0.0155,0.0174,0.496,"+/0","HDAC8 inhibitor","HDAC8","Differentiating.epigenetic modifier"]
["HLA-DRB1","Vorinostat",-0.434,0.03,0.347,0.188,2.36,0.0181,0.0195,0.496,"-/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["LDLR","Tubastatin_A",-0.312,0.128,0.504,0.0466,2.51,0.0121,0.0134,0.496,"0/+","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["RIOX1","Lovastatin",-0.0894,0.671,-0.763,0.000584,-2.61,0.00899,0.0106,0.496,"0/-","HMG-CoA reductase inhibitor","HMGCR","Metabolic modifier"]
["RPL32","Tacrolimus",-0.297,0.15,0.542,0.03,2.61,0.00902,0.0106,0.496,"0/+","binds FKBP12, causes inhibition of calcineurin","FKBP1A","Rapalog"]
["TMED9","VER_155008",-0.222,0.286,0.493,0.0522,2.19,0.0285,0.0287,0.496,"0/0","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["ACAA1","Methotrexate",-0.154,0.462,0.517,0.0404,2.08,0.0376,0.0362,0.497,"0/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["CTBP2","Fingolimod",-0.426,0.0337,0.372,0.156,2.42,0.0156,0.0176,0.497,"-/0","S1PR antagonist","S1PR1","Other"]
["FAM107B","GSK_1070916",0.0942,0.654,0.726,0.00145,2.36,0.0183,0.0197,0.497,"0/+","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["MPP6","Lonafarnib",0.28,0.175,-0.527,0.0358,-2.5,0.0125,0.0137,0.497,"0/-","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["PHF14","AMG319",0.438,0.0287,-0.38,0.147,-2.48,0.013,0.0146,0.497,"+/0","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["SPTBN2","Erdafitinib",0.188,0.367,-0.519,0.0393,-2.19,0.0286,0.0288,0.497,"0/-","FGFR inhibitor","FGFR1;FGFR2;FGFR3;FGFR4","Kinase inhibitor"]
["TRAK1","Merestinib",-0.548,0.00457,0.206,0.444,2.36,0.0184,0.0188,0.497,"-/0","MET inhibitor","MET","Kinase inhibitor"]
["BUB1B","Docetaxel",0.681,0.000177,0.106,0.697,-2.07,0.0381,0.0366,0.498,"+/0","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["AP2B1","Pemetrexed",-0.289,0.161,0.403,0.122,2.07,0.0383,0.0368,0.498,"0/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["DNAJC8","Pracinostat",-0.224,0.282,0.548,0.0279,2.41,0.0158,0.0178,0.498,"0/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["FAM102B","Omipalisib",-0.133,0.525,-0.744,0.000956,-2.36,0.0184,0.0198,0.498,"0/-","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["GID4","Carboplatin",0.335,0.101,-0.442,0.0863,-2.35,0.0185,0.02,0.498,"0/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["HAUS8","THZ2",-0.475,0.0163,0.296,0.265,2.35,0.0187,0.0201,0.498,"-/0","CDK7 inhibitor","CDK7","Kinase inhibitor"]
["KNL1","OSU_03012",0.458,0.0212,-0.36,0.171,-2.49,0.0127,0.0139,0.498,"+/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["ST8SIA4","PCI_34051",-0.0362,0.864,0.622,0.0101,2.19,0.0289,0.0291,0.498,"0/+","HDAC8 inhibitor","HDAC8","Differentiating.epigenetic modifier"]
["UBASH3B","Omaveloxolone",-0.154,0.462,0.584,0.0177,2.35,0.0186,0.0189,0.498,"0/+","Nrf2 activator","NFE2L2","Other"]
["ADRM1","Thioguanine",0.414,0.0398,-0.277,0.299,-2.07,0.0384,0.0369,0.499,"+/0","Antimetabolite, Purine analog","DNMT1","Conv.Chemo"]
["ABL1","Pacritinib",-0.278,0.179,0.412,0.113,2.07,0.0386,0.0372,0.499,"0/0","FLT3, JAK2 inhibitor","FLT3;JAK2;TYK2","Kinase inhibitor"]
["DAPK1","RO5126766",0.141,0.5,-0.604,0.0132,-2.41,0.0161,0.0181,0.499,"0/-","dual RAF and MEK inhibitor","RAF1;BRAF;MAP2K1;MAP2K2","Kinase inhibitor"]
["CSPP1","Saracatinib",0.439,0.0282,-0.355,0.178,-2.41,0.0161,0.0182,0.499,"+/0","Src, ABL inhibitor","ABL1;SRC;LCK;YES1;LYN;FYN;BLK;EGFR;KIT;EPHA2","Kinase inhibitor"]
["CRY1","Triapine",0.308,0.134,-0.479,0.0607,-2.4,0.0163,0.0184,0.499,"0/0","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["DNAJB14","Deferoxamine",0.154,0.461,-0.594,0.0153,-2.4,0.0165,0.0185,0.499,"0/-","Iron chelator","APP","Other"]
["EFTUD2","Vistusertib",0.143,0.496,-0.6,0.0139,-2.39,0.0167,0.0187,0.499,"0/-","mTOR inhibitor, ATP-competitive","MTOR","Kinase inhibitor"]
["EML3","Mitoxantrone",-0.1,0.633,0.617,0.0108,2.35,0.0189,0.0203,0.499,"0/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["ISL2","PIM_447",0.0941,0.655,-0.651,0.00633,-2.49,0.0128,0.014,0.499,"0/-","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["NOP10","Givinostat",-0.374,0.0654,0.442,0.0866,2.48,0.0131,0.0147,0.499,"0/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC10","Differentiating.epigenetic modifier"]
["STING1","Sunitinib",0.829,{"v":3.02e-07,"d":"3.02E-07"},0.399,0.126,-2.18,0.0292,0.0294,0.499,"+/0","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["TTC30B","Panobinostat",0.407,0.0434,-0.371,0.157,-2.35,0.0188,0.0191,0.499,"+/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["BRK1","Trifluridine",-0.602,0.00144,0.0252,0.926,2.06,0.039,0.0375,0.5,"-/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["C7orf25","Buparlisib",0.114,0.587,-0.542,0.0301,-2.06,0.0391,0.0376,0.5,"0/-","PI3K inhibitor, pan-class I","PIK3CA;PIK3CB;PIK3CG;PIK3CD;MTOR;PIK3C3","Kinase inhibitor"]
["ACSF2","Dactinomycin",-0.32,0.119,0.37,0.159,2.06,0.0396,0.038,0.5,"0/0","RNA and DNA synthesis inhibitor","DNA","Conv.Chemo"]
["CUTC","Ravoxertinib",0.157,0.453,-0.59,0.0161,-2.39,0.0168,0.0188,0.5,"0/-","ERK inhibitor","MAPK3","Kinase inhibitor"]
["INCENP","Tozasertib",0.405,0.0448,-0.414,0.111,-2.49,0.0129,0.0142,0.5,"+/0","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["RFX3","UCN_01",0.51,0.00921,-0.333,0.207,-2.6,0.00934,0.0109,0.5,"+/0","PKCbeta, PDK1, Chk, Cdk2 inhibitor","PRKCB;PDPK1","Kinase inhibitor"]
["SMG9","C646",-0.527,0.00681,0.175,0.517,2.18,0.0292,0.0295,0.5,"-/0","EP300, CREB-binding protein (CBP) inhibitor","EP300","Differentiating.epigenetic modifier"]
["YME1L1","AT9283",0.285,0.167,-0.483,0.0578,-2.35,0.019,0.0193,0.5,"0/0","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["ZNF507","Azacitidine",0.597,0.00162,-0.13,0.631,-2.34,0.0191,0.0194,0.5,"+/0","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["CDKN2D","Abexinostat",0.387,0.056,-0.403,0.122,-2.39,0.0169,0.0189,0.501,"0/0","HDAC1 selective inhibitor","HDAC1","Differentiating.epigenetic modifier"]
["DOK2","AZD_1080",-0.174,0.406,0.578,0.019,2.39,0.017,0.019,0.501,"0/+","GSK3 inhibitor","GSK3B;GSK3A","Kinase inhibitor"]
["FASTK","Lifirafenib_BGB_283",0.296,0.151,-0.472,0.0647,-2.34,0.0194,0.0208,0.501,"0/0","Raf inhibitor","RAF1;BRAF;EGFR","Kinase inhibitor"]
["INTS13","Flutamide",-0.215,0.302,0.572,0.0207,2.48,0.0131,0.0143,0.501,"0/+","Nonsteroidal antiandrogen","AR;AHR;NR1I2","Hormone therapy"]
["PCCB","AZD1208",-0.168,0.422,0.601,0.0137,2.47,0.0134,0.0151,0.501,"0/+","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["PKIG","Oxaliplatin",-0.466,0.0188,0.344,0.192,2.47,0.0135,0.0152,0.501,"-/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["RPS6KA4","Raltitrexed",-0.194,0.352,0.612,0.0117,2.6,0.00937,0.011,0.501,"0/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["RNFT1","MK_8745",-0.241,0.245,0.579,0.0187,2.59,0.00948,0.0111,0.501,"0/+","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["STOM","NVP_CGM097",-0.11,0.602,0.572,0.0205,2.18,0.0295,0.0298,0.501,"0/+","p53-MDM2 inhibitor","TP53;MDM2","Apoptotic modulator"]
["VPS29","Cytarabine.Idarubicin",-0.449,0.0243,0.324,0.221,2.34,0.0192,0.0195,0.501,"-/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["BTN3A2","Vismodegib",0.399,0.0483,-0.288,0.279,-2.05,0.0399,0.0384,0.502,"+/0","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["C12orf43","VE_821",0.0507,0.81,-0.583,0.0177,-2.05,0.0402,0.0386,0.502,"0/-","ATR inihibitor","ATR","Kinase inhibitor"]
["ABCC4","ODM_201",0.279,0.177,-0.406,0.118,-2.05,0.0403,0.0387,0.502,"0/0","AR antagonist","AR","Hormone therapy"]
["DCD","TGX_221",-0.23,0.268,0.537,0.0321,2.38,0.0172,0.0192,0.502,"0/+","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["MNX1","PD0325901",0.511,0.00904,-0.293,0.271,-2.48,0.0133,0.0145,0.502,"+/0","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["PYROXD1","Gemcitabine",0.639,0.000581,-0.147,0.587,-2.59,0.00968,0.0113,0.502,"+/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["TIGAR","Toremifene",-0.507,0.00963,0.198,0.463,2.17,0.0299,0.0301,0.502,"-/0","Selective estrogen receptor modulator","ESR1;SHBG","Hormone therapy"]
["YJU2","Prexasertib",0.558,0.00378,-0.186,0.491,-2.34,0.0195,0.0198,0.502,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ARL6IP4","PAC_1",0.5,0.0108,-0.165,0.542,-2.05,0.0406,0.039,0.503,"+/0","procaspase-3 activator","CASP3","Apoptotic modulator"]
["CARNMT1","Pexidartinib",0.559,0.00366,-0.0837,0.758,-2.05,0.0408,0.0391,0.503,"+/0","KIT, CSF1R, FLT3 inhibitor","CSF1R;FLT3;KIT","Kinase inhibitor"]
["CNTROB","Spebrutinib",-0.488,0.0134,0.291,0.275,2.38,0.0174,0.0193,0.503,"-/0","BTK inhibitor","BTK","Kinase inhibitor"]
["FBXL15","PD0325901",0.204,0.329,-0.543,0.0297,-2.33,0.0198,0.0211,0.503,"0/-","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["MYL4","PFI_1",0.376,0.0637,-0.434,0.0934,-2.46,0.014,0.0156,0.503,"0/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["TMEM259","Afuresertib",-0.241,0.246,0.472,0.0648,2.17,0.0301,0.0303,0.503,"0/0","AKT1-selective inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["ZBTB39","TAK_901",0.518,0.00797,-0.237,0.376,-2.33,0.0197,0.02,0.503,"+/0","Aurora, Src family, JAK3, RTK inhibitor","AURKA;AURKB;JAK3;SRC;CLK2;FGR;LRRK2;YES1;LCK;FYN;ABL1;AXL;ABL2;HCK;RET;FRK;NTRK1;FGFR2","Kinase inhibitor"]
["ZPR1","Niraparib",0.306,0.137,-0.461,0.072,-2.33,0.0199,0.0201,0.503,"0/0","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["ADIPOR1","Pracinostat",-0.22,0.291,0.455,0.0768,2.04,0.0412,0.0395,0.504,"0/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["CLPB","Digoxin",-0.182,0.383,0.569,0.0214,2.37,0.0176,0.0196,0.504,"0/+","Cardiac glycoside","ATP1A1;ITGB1;ITGB3;ITGA3;ITGA1","Other"]
["HYPK","Prexasertib",0.703,{"v":8.76e-05,"d":"8.76E-05"},0.00897,0.974,-2.47,0.0134,0.0147,0.504,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["NRBF2","Megestrol_acetate",-0.47,0.0178,0.335,0.205,2.45,0.0141,0.0158,0.504,"-/0","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["STMN2","Birinapant",0.65,0.00044,0.0179,0.948,-2.16,0.0305,0.0306,0.504,"+/0","IAPs, SMAC mimetic","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["STOM","Palbociclib",-0.323,0.116,0.398,0.127,2.16,0.0307,0.0308,0.504,"0/0","Topoisomerase I inhibitor, Camptothecin analog","CDK4;CDK6","Kinase inhibitor"]
["SHFL","Cytarabine.Idarubicin",-0.452,0.0234,0.262,0.327,2.16,0.0308,0.031,0.504,"-/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["TPRKB","Cladribine",-0.353,0.083,0.417,0.108,2.33,0.02,0.0203,0.504,"0/0","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["BSCL2","MK_2206",0.0199,0.925,-0.6,0.0139,-2.04,0.0414,0.0397,0.505,"0/-","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["CORO1A","Decitabine",-0.392,0.0524,0.393,0.132,2.37,0.0177,0.0197,0.505,"0/0","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["CPD","Ribociclib",0.589,0.00194,-0.151,0.577,-2.37,0.0179,0.0199,0.505,"+/0","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["HIPK3","Ibrutinib",-0.367,0.0711,0.404,0.121,2.32,0.0201,0.0215,0.505,"0/0","BTK inhibitor","BTK;BLK;EGFR;FYN;LYN;LCK;BRAF;WNK1","Kinase inhibitor"]
["GNG2","Eltanexor",-0.272,0.188,0.488,0.0553,2.32,0.0202,0.0216,0.505,"0/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["GPAA1","Olaparib",-0.418,0.0374,0.35,0.185,2.32,0.0205,0.0218,0.505,"-/0","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["ING1","Crenolanib",-0.523,7.26E-3,0.275,0.302,2.47,0.0136,0.0148,0.505,"-/0","PDGFRA and PDGFRB inhibitor","PDGFRA","Kinase inhibitor"]
["POLA1","PCI_34051",0.456,0.0218,-0.349,0.185,-2.45,0.0142,0.016,0.505,"+/0","HDAC8 inhibitor","HDAC8","Differentiating.epigenetic modifier"]
["TMEM39A","SB743921",-0.0881,0.675,0.582,0.0179,2.16,0.0311,0.0312,0.505,"0/+","Mitotic inhibitor, Eg5, KSP inhibitor","KIF11","Kinesin inhibitor"]
["TBC1D24","Cisplatin",-0.293,0.155,0.423,0.102,2.16,0.0311,0.0313,0.505,"0/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["TTC37","Tivantinib",-0.0211,0.92,0.66,0.00542,2.33,0.02,0.0203,0.505,"0/+","MET inhibitor","MET","Kinase inhibitor"]
["ADAT1","Bosutinib",0.347,0.0892,-0.336,0.203,-2.04,0.0418,0.0401,0.506,"0/0","ABL, Src inhibitor","ABL1;LYN;HCK;SRC;EPHB2;NTRK1;NTRK2;TXK","Kinase inhibitor"]
["CCDC127","Resminostat",-0.262,0.205,0.416,0.109,2.03,0.0419,0.0401,0.506,"0/0","HDAC1, 3, 6 inhibitor","HDAC1;HDAC3;HDAC6","Differentiating.epigenetic modifier"]
["CHMP1A","Doxorubicin",0.474,0.0167,-0.302,0.256,-2.36,0.0181,0.0202,0.506,"+/0","Topoisomerase II inhibitor","TOP2A;NOLC1","Conv.Chemo"]
["LARS1","GSK923295",0.404,0.0453,-0.408,0.117,-2.46,0.0138,0.0151,0.506,"+/0","CENP-E inhibitor","CENPE","Kinesin inhibitor"]
["KDM6B","LY_2874455",0.255,0.219,-0.537,0.0319,-2.46,0.0139,0.0152,0.506,"0/-","FGFR inhibitor","FGFR1;FGFR2;FGFR3","Kinase inhibitor"]
["MTG2","Agerafenib_CEP_32496",0.558,0.00375,-0.223,0.407,-2.45,0.0143,0.0161,0.506,"+/0","BRAF(V600E) inhibitor","BRAF;RAF1;KIT;RET;LCK;ABL1;PDGFRB;CSF1R;MET;EGFR;KDR;EPHA2","Kinase inhibitor"]
["PIKFYVE","Erdafitinib",-0.108,0.606,-0.746,0.000915,-2.44,0.0146,0.0163,0.506,"0/-","FGFR inhibitor","FGFR1;FGFR2;FGFR3;FGFR4","Kinase inhibitor"]
["PPIP5K1","Abexinostat",-0.197,0.346,0.604,0.0132,2.57,0.0102,0.0118,0.506,"0/+","HDAC1 selective inhibitor","HDAC1","Differentiating.epigenetic modifier"]
["SIGIRR","Midostaurin",-0.179,0.392,0.516,0.0406,2.15,0.0315,0.0316,0.506,"0/+","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["XIAP","Toremifene",-0.406,0.044,0.364,0.166,2.32,0.0203,0.0206,0.506,"-/0","Selective estrogen receptor modulator","ESR1;SHBG","Hormone therapy"]
["TRIM62","Resminostat",0.294,0.154,-0.469,0.067,-2.32,0.0204,0.0207,0.506,"0/0","HDAC1, 3, 6 inhibitor","HDAC1;HDAC3;HDAC6","Differentiating.epigenetic modifier"]
["USP27X","Alpelisib",0.341,0.0956,-0.426,0.1,-2.31,0.0206,0.0209,0.506,"0/0","PI3Kalpha selective inhibitor","PIK3CA","Kinase inhibitor"]
["WASHC1","Prexasertib",-0.502,0.0105,0.25,0.35,2.31,0.0209,0.0211,0.506,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["ATP6AP1","Eribulin",-0.254,0.22,0.423,0.103,2.03,0.0422,0.0405,0.507,"0/0","Mitotic inhibitor, microtubule depolymerizer","TUBB1","Conv.Chemo"]
["CASC3","Ibrutinib",0.205,0.325,-0.464,0.0706,-2.03,0.0424,0.0406,0.507,"0/0","BTK inhibitor","BTK;BLK;EGFR;FYN;LYN;LCK;BRAF;WNK1","Kinase inhibitor"]
["CD74","AMG_925",-0.182,0.384,0.566,0.0222,2.36,0.0183,0.0203,0.507,"0/+","FLT3, CDK4 inhibitor","FLT3;CDK4","Kinase inhibitor"]
["EEPD1","AZD3965",-0.282,0.173,0.49,0.0542,2.36,0.0183,0.0204,0.507,"0/0","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["GAB1","GSK2656157",0.288,0.162,-0.472,0.065,-2.31,0.0207,0.0221,0.507,"0/0","PERK inhibitor","EIF2AK3","Kinase inhibitor"]
["EPS15","BIIB021",-0.639,0.000584,0.0515,0.85,2.31,0.0209,0.0223,0.507,"-/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["MFSD4B","Rocilinostat",-0.344,0.0923,0.462,0.0719,2.45,0.0142,0.0155,0.507,"0/0","HDAC6 selective inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["MCPH1","Navitoclax",-0.398,0.0485,0.409,0.116,2.45,0.0144,0.0157,0.507,"-/0","Bcl-2,Bcl-XL inhibitor","BCL2;BCL2L2;BAD;BCL2L1;MCL1","Apoptotic modulator"]
["SLC39A11","Vincristine",-0.441,0.0274,0.271,0.31,2.15,0.0318,0.0319,0.507,"-/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB;TUBA4A","Conv.Chemo"]
["SLC44A1","Dactinomycin",0.639,0.000586,0.00563,0.983,-2.15,0.0319,0.032,0.507,"+/0","RNA and DNA synthesis inhibitor","DNA","Conv.Chemo"]
["SORD","NVP_CGM097",-0.392,0.0526,0.324,0.221,2.14,0.032,0.0322,0.507,"0/0","p53-MDM2 inhibitor","TP53;MDM2","Apoptotic modulator"]
["TOMM34","Dabrafenib",0.359,0.078,-0.356,0.175,-2.14,0.0324,0.0325,0.507,"0/0","BRAF(V600E) inhibitor","BRAF;RAF1","Kinase inhibitor"]
["YY2","Tubastatin_A",-0.375,0.0649,0.391,0.134,2.31,0.021,0.0213,0.507,"0/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["WDR45B","Buparlisib",-0.187,0.372,0.55,0.0273,2.31,0.021,0.0213,0.507,"0/+","PI3K inhibitor, pan-class I","PIK3CA;PIK3CB;PIK3CG;PIK3CD;MTOR;PIK3C3","Kinase inhibitor"]
["DARS2","AZD_6482",0.0621,0.768,0.709,0.0021,2.35,0.0186,0.0207,0.508,"0/+","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["CFL1","Bosutinib",-0.289,0.161,0.481,0.0592,2.35,0.0188,0.0208,0.508,"0/0","ABL, Src inhibitor","ABL1;LYN;HCK;SRC;EPHB2;NTRK1;NTRK2;TXK","Kinase inhibitor"]
["DAB2","PCI_34051",-0.541,0.0052,0.212,0.431,2.35,0.0189,0.0209,0.508,"-/0","HDAC8 inhibitor","HDAC8","Differentiating.epigenetic modifier"]
["GSDME","Litronesib",0.403,0.0459,-0.363,0.167,-2.31,0.0211,0.0224,0.508,"+/0","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["HIRA","Digoxin",-0.386,0.0566,0.378,0.148,2.3,0.0213,0.0227,0.508,"0/0","Cardiac glycoside","ATP1A1;ITGB1;ITGB3;ITGA3;ITGA1","Other"]
["MORC4","Selinexor",0.184,0.379,-0.584,0.0176,-2.44,0.0146,0.0159,0.508,"0/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["NFATC4","Galiellalactone",0.606,1.32E-3,-0.148,0.584,-2.43,0.0149,0.0166,0.508,"+/0","STAT3-DNA interaction inhibitor","STAT3","Other"]
["TMX4","OTS167",0.367,0.0709,-0.347,0.188,-2.14,0.0326,0.0327,0.508,"0/0","MELK inhibitor","MELK","Kinase inhibitor"]
["SH3BGRL","Masitinib",-0.204,0.329,0.493,0.0522,2.14,0.0327,0.0328,0.508,"0/0","KIT inhibitor","KIT","Kinase inhibitor"]
["TSHZ1","Abexinostat",-0.464,0.0193,0.294,0.268,2.3,0.0212,0.0214,0.508,"-/0","HDAC1 selective inhibitor","HDAC1","Differentiating.epigenetic modifier"]
["VHL","Danusertib",0.404,0.0455,-0.361,0.17,-2.3,0.0213,0.0216,0.508,"+/0","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["ASRGL1","RO5126766",0.169,0.418,-0.49,0.0539,-2.02,0.0432,0.0413,0.509,"0/0","dual RAF and MEK inhibitor","RAF1;BRAF;MAP2K1;MAP2K2","Kinase inhibitor"]
["CTTN","THZ2",0.0947,0.652,-0.62,0.0104,-2.35,0.019,0.0211,0.509,"0/-","CDK7 inhibitor","CDK7","Kinase inhibitor"]
["DALRD3","ML390",0.482,0.0146,-0.285,0.286,-2.34,0.0193,0.0213,0.509,"+/0","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["DUSP3","GSK2656157",-0.121,0.563,0.602,0.0136,2.34,0.0193,0.0213,0.509,"0/+","PERK inhibitor","EIF2AK3","Kinase inhibitor"]
["MLLT3","Seliciclib",-0.295,0.152,0.5,0.0487,2.44,0.0148,0.016,0.509,"0/+","CDK2, 7, 9 inhibitor","CDK2;CDK1;CDK5;MAPK1;MAPK3","Kinase inhibitor"]
["NRROS","Pomalidomide",0.0775,0.713,-0.649,0.00656,-2.43,0.015,0.0167,0.509,"0/-","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["RGS19","SN_38",-0.131,0.532,0.643,0.00723,2.56,0.0105,0.0122,0.509,"0/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["STAU1","Birabresib",0.285,0.168,-0.424,0.101,-2.13,0.0331,0.0331,0.509,"0/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["XXYLT1","Birinapant",-0.436,0.0294,0.325,0.219,2.3,0.0214,0.0217,0.509,"-/0","IAPs, SMAC mimetic","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["TXNRD3","AZD6738",-0.45,0.0239,0.309,0.245,2.3,0.0215,0.0218,0.509,"-/0","ATR inihibitor","ATR","Kinase inhibitor"]
["TTC13","C646",0.625,0.000828,-0.0686,0.801,-2.29,0.0218,0.022,0.509,"+/0","EP300, CREB-binding protein (CBP) inhibitor","EP300","Differentiating.epigenetic modifier"]
["C5orf15","AMG_925",0.325,0.112,-0.353,0.18,-2.02,0.0435,0.0417,0.51,"0/0","FLT3, CDK4 inhibitor","FLT3;CDK4","Kinase inhibitor"]
["ARMC6","ZSTK474",0.146,0.485,-0.506,0.0453,-2.02,0.0438,0.0419,0.51,"0/-","PI3K gamma selective inhibitor","PIK3CG","Kinase inhibitor"]
["BRAP","AZD_6482",0.211,0.311,-0.454,0.0771,-2.01,0.044,0.0422,0.51,"0/0","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["CRMP1","Acalabrutinib",-0.568,0.00307,0.171,0.526,2.34,0.0195,0.0215,0.51,"-/0","BTK inhibitor","BTK","Kinase inhibitor"]
["EXOC4","Midostaurin",-0.315,0.125,0.444,0.0848,2.3,0.0216,0.023,0.51,"0/0","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["HNRNPH1","ABT_751",0.337,0.0994,-0.422,0.103,-2.29,0.022,0.0233,0.51,"0/0","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["PM20D2","Mocetinostat",-0.494,0.012,0.299,0.261,2.43,0.0151,0.0168,0.51,"-/0","HDAC inhibitor (HDAC1 and 2-selective)","HDAC1;HDAC2;HDAC3;HDAC11","Differentiating.epigenetic modifier"]
["NMRAL1","SAR405838",-0.257,0.215,0.528,0.0357,2.43,0.0151,0.0169,0.51,"0/+","MDM2 inhibitor","MDM2;TP53","Apoptotic modulator"]
["SUMF1","FRAX486",-0.184,0.378,0.506,0.0453,2.13,0.0334,0.0334,0.51,"0/+","PAK1, 2, 3 inhibitor","PAK1","Kinase inhibitor"]
["UBE2N","CEP_37440",-0.276,0.182,0.476,0.0623,2.29,0.0221,0.0222,0.51,"0/0","ALK inhibitor","ALK;AXL;MET;TYRO3;MERTK;KDR;DDR1","Kinase inhibitor"]
["VCL","Encorafenib",-0.465,0.0191,0.288,0.279,2.29,0.0222,0.0223,0.51,"-/0","BRAF(V600E) inhibitor","BRAF;RAF1","Kinase inhibitor"]
["ACTR2","AZD8055",-0.258,0.213,0.413,0.112,2.01,0.0443,0.0423,0.511,"0/0","mTOR inhibitor","MTOR","Kinase inhibitor"]
["ASL","Temsirolimus",-0.157,0.453,0.496,0.0508,2.01,0.0447,0.0427,0.511,"0/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["DIMT1","PF_670462",0.23,0.269,-0.525,0.0368,-2.34,0.0195,0.0215,0.511,"0/-","CK1epsilon and CK1delta inhibitor","CSNK1D;CSNK1E","Kinase inhibitor"]
["GTDC1","AZD1208",0.379,0.0617,-0.381,0.146,-2.29,0.0223,0.0236,0.511,"0/0","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["MRFAP1L1","Vistusertib",0.374,0.0653,-0.428,0.0986,-2.43,0.0151,0.0163,0.511,"0/0","mTOR inhibitor, ATP-competitive","MTOR","Kinase inhibitor"]
["SLC15A4","PF_00477736",0.197,0.345,-0.496,0.0509,-2.12,0.0336,0.0337,0.511,"0/0","CHEK1 inhibitor","CHEK1;KDR;FLT3;YES1;CHEK2","Kinase inhibitor"]
["TULP3","RGFP966",0.261,0.208,-0.487,0.0558,-2.28,0.0224,0.0225,0.511,"0/0","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["ZXDC","Dactinomycin",0.272,0.188,-0.477,0.0619,-2.28,0.0225,0.0226,0.511,"0/0","RNA and DNA synthesis inhibitor","DNA","Conv.Chemo"]
["CARS2","Tamatinib",0.341,0.0949,-0.333,0.208,-2.01,0.0448,0.0429,0.512,"0/0","SYK inhibitor","SYK","Kinase inhibitor"]
["APBB1IP","Erlotinib",0.158,0.451,-0.495,0.0515,-2,0.045,0.0431,0.512,"0/0","EGFR inhibitor","EGFR","Kinase inhibitor"]
["ABHD14B","Gemcitabine",-0.287,0.164,0.384,0.142,2,0.0452,0.0433,0.512,"0/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["FLT1","GSK_2334470",0.293,0.156,-0.46,0.0729,-2.28,0.0224,0.0237,0.512,"0/0","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["GTF2H1","Sitravatinib",0.368,0.0699,-0.39,0.135,-2.28,0.0225,0.0239,0.512,"0/0","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["EYA3","Prexasertib",0.598,0.0016,-0.107,0.693,-2.28,0.0227,0.0241,0.512,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["MID1","UNC0638",0.262,0.206,-0.524,0.0372,-2.43,0.0151,0.0164,0.512,"0/-","G9a, GLP inhibitor","EHMT2","Differentiating.epigenetic modifier"]
["NECAP1","Resminostat",0.358,0.0787,-0.44,0.0883,-2.42,0.0155,0.0172,0.512,"0/0","HDAC1, 3, 6 inhibitor","HDAC1;HDAC3;HDAC6","Differentiating.epigenetic modifier"]
["PROSER1","Clofarabine",0.308,0.135,-0.516,0.0406,-2.54,0.011,0.0127,0.512,"0/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["SSR1","Tubacin",-0.442,0.027,0.26,0.33,2.12,0.0341,0.0341,0.512,"-/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["SLC9A3R1","Resminostat",-0.23,0.269,0.468,0.0677,2.12,0.0341,0.0342,0.512,"0/0","HDAC1, 3, 6 inhibitor","HDAC1;HDAC3;HDAC6","Differentiating.epigenetic modifier"]
["TMEM243","Thioguanine",-0.242,0.243,0.457,0.0753,2.12,0.0343,0.0343,0.512,"0/0","Antimetabolite, Purine analog","DNMT1","Conv.Chemo"]
["ZZEF1","Vinorelbine",-0.415,0.0392,0.341,0.196,2.28,0.0227,0.0229,0.512,"-/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["WAPL","JQ1",0.376,0.0637,-0.38,0.147,-2.27,0.023,0.0231,0.512,"0/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["AP1G1","Silmitasertib",0.169,0.418,-0.485,0.0569,-2,0.0453,0.0433,0.513,"0/0","CSNK2A1 inhibitor","CSNK2A1","Kinase inhibitor"]
["BCL11A","Gemcitabine",-0.47,0.0178,0.187,0.487,2,0.0456,0.0435,0.513,"-/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["ATG5","NVP_BHG712",-0.143,0.495,0.504,0.0465,2,0.0458,0.0437,0.513,"0/+","EphB4 inhibitor","EPHB4","Kinase inhibitor"]
["DNM3","Oxaliplatin",-0.393,0.0518,0.379,0.148,2.33,0.0199,0.0219,0.513,"0/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["CHD2","Filanesib",-0.218,0.294,0.531,0.0342,2.33,0.02,0.0221,0.513,"0/+","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["CENPO","RGFP966",0.36,0.0775,-0.41,0.114,-2.32,0.0202,0.0222,0.513,"0/0","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["FAAH","Trametinib",0.311,0.13,-0.44,0.0879,-2.27,0.0231,0.0244,0.513,"0/0","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["PHF5A","BMS_754807",0.215,0.302,-0.557,0.0251,-2.42,0.0155,0.0173,0.513,"0/-","IGF1R inhibitor","IGF1R","Kinase inhibitor"]
["MTHFSD","Indibulin",0.347,0.0894,-0.449,0.0811,-2.42,0.0157,0.0174,0.513,"0/0","Mitoric inhibitor, Microtubule depolymerizer","TUBB","Conv.Chemo"]
["RBFA","Buparlisib",-0.18,0.389,0.608,0.0126,2.54,0.0112,0.0129,0.513,"0/+","PI3K inhibitor, pan-class I","PIK3CA;PIK3CB;PIK3CG;PIK3CD;MTOR;PIK3C3","Kinase inhibitor"]
["SLC9B2","PCI_34051",0.152,0.469,-0.527,0.0361,-2.11,0.0348,0.0348,0.513,"0/-","HDAC8 inhibitor","HDAC8","Differentiating.epigenetic modifier"]
["TTK","Dasatinib",0.203,0.331,-0.529,0.0352,-2.27,0.0232,0.0233,0.513,"0/-","ABL, Src, Kit, EphR Inhibitor","ABL1","Kinase inhibitor"]
["UBA1","Nilotinib",0.306,0.137,-0.445,0.0845,-2.27,0.0233,0.0234,0.513,"0/0","ABL inhibitor","ABL1;KIT","Kinase inhibitor"]
["ARID4A","Gemcitabine",-0.471,0.0176,0.185,0.493,2,0.046,0.044,0.514,"-/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["CAPN1","THZ2",0.0709,0.736,0.646,0.00686,1.99,0.0462,0.0441,0.514,"0/+","CDK7 inhibitor","CDK7","Kinase inhibitor"]
["DARS1","ABT_751",0.676,0.00021,0.00887,0.974,-2.32,0.0203,0.0223,0.514,"+/0","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["CD47","Tozasertib",-0.621,0.000917,0.0837,0.758,2.32,0.0204,0.0225,0.514,"-/0","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["FXR1","Clofarabine",0.251,0.226,-0.491,0.0537,-2.27,0.0233,0.0247,0.514,"0/0","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["IRF2BPL","Methotrexate",0.157,0.453,-0.598,0.0145,-2.42,0.0153,0.0166,0.514,"0/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["MAML3","Canertinib",-0.197,0.344,0.57,0.0213,2.42,0.0155,0.0168,0.514,"0/+","Pan-HER inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["PLGRKT","Daunorubicin",0.0729,0.729,-0.647,6.77E-3,-2.41,0.016,0.0177,0.514,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["PCGF3","SAR405838",-0.547,0.00469,0.225,0.403,2.41,0.016,0.0178,0.514,"-/0","MDM2 inhibitor","MDM2;TP53","Apoptotic modulator"]
["OTUD3","NVP_BGT226",0.0659,0.754,-0.649,0.00648,-2.4,0.0163,0.0181,0.514,"0/-","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CG;MTOR","Kinase inhibitor"]
["MTMR2","Thioguanine",0.323,0.115,-0.465,0.0695,-2.4,0.0164,0.0182,0.514,"0/0","Antimetabolite, Purine analog","DNMT1","Conv.Chemo"]
["TMEM175","SN_38",-0.521,0.00754,0.157,0.562,2.1,0.0353,0.0353,0.514,"-/0","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["SLC39A14","RGFP966",0.51,0.00917,-0.171,0.527,-2.1,0.0355,0.0354,0.514,"+/0","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["UAP1","Alisertib",0.467,0.0185,-0.278,0.297,-2.27,0.0235,0.0236,0.514,"+/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["TRIM4","Cytarabine",-0.367,0.0711,0.386,0.14,2.26,0.0236,0.0237,0.514,"0/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["CAT","Pexidartinib",-0.334,0.103,0.336,0.204,1.99,0.0466,0.0445,0.515,"0/0","KIT, CSF1R, FLT3 inhibitor","CSF1R;FLT3;KIT","Kinase inhibitor"]
["CAMK2D","SN_38",0.194,0.353,-0.461,0.072,-1.99,0.0467,0.0447,0.515,"0/0","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["ARHGAP32","AZD_8186",0.301,0.143,-0.367,0.163,-1.99,0.0469,0.0448,0.515,"0/0","PI3K beta inhibitor","PIK3CG","Kinase inhibitor"]
["CHERP","Vidofludimus",0.34,0.096,-0.425,0.1,-2.31,0.0208,0.0228,0.515,"0/0","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["GNG2","Glesatinib",-0.283,0.17,0.462,0.0714,2.26,0.0236,0.025,0.515,"0/0","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["FBXW4","Floxuridine",0.234,0.259,-0.502,0.0474,-2.26,0.0237,0.025,0.515,"0/-","Antimetabolite, Analog of 5-fluorouracil","TYMS","Conv.Chemo"]
["KSR1","Brigatinib",0.192,0.358,-0.572,0.0205,-2.42,0.0157,0.017,0.515,"0/-","ALK inhibitor, including gatekeeper mutant ALK","ALK;ROS1;IGF1R;EGFR;INSR;ABL1;FLT3;MET;ERBB2;ERBB4","Kinase inhibitor"]
["RPF1","ZSTK474",0.347,0.0888,-0.48,0.0601,-2.53,0.0114,0.0131,0.515,"0/0","PI3K gamma selective inhibitor","PIK3CG","Kinase inhibitor"]
["RELL1","Gedatolisib",-0.46,0.0207,0.369,0.159,2.53,0.0115,0.0132,0.515,"-/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CG;MTOR","Kinase inhibitor"]
["SIPA1","Tozasertib",-0.297,0.15,0.404,0.121,2.1,0.0359,0.0358,0.515,"0/0","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["TPM2","Danusertib",-0.438,0.0284,0.31,0.242,2.26,0.0238,0.0239,0.515,"-/0","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["WDR24","CCT196969",-0.273,0.187,0.47,0.0661,2.26,0.0239,0.024,0.515,"0/0","pan-RAF, Src inhibitor","RAF1;BRAF;SRC;LCK","Kinase inhibitor"]
["ATP5PD","ARV_825",0.434,0.0301,-0.226,0.4,-1.99,0.047,0.0449,0.516,"+/0","BET-targeting PROTAC","BRD4","Differentiating.epigenetic modifier"]
["CBFA2T2","SN_38",-0.0488,0.817,-0.631,0.00879,-1.98,0.0473,0.0452,0.516,"0/-","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["ACTBL2","Tamatinib",-0.307,0.136,0.36,0.171,1.98,0.0475,0.0453,0.516,"0/0","SYK inhibitor","SYK","Kinase inhibitor"]
["CDK11B","Asciminib",0.286,0.166,-0.472,0.0647,-2.31,0.021,0.0231,0.516,"0/0","Allosteric ABL inhibitor, blocks myristoyl binding","ABL1","Kinase inhibitor"]
["FBXL14","Tubacin",0.311,0.131,-0.438,0.0901,-2.26,0.0238,0.0252,0.516,"0/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["MFAP1","Prexasertib",0.365,0.073,-0.432,0.0951,-2.41,0.0158,0.0171,0.516,"0/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["NUCB1","Mercaptopurine",-0.283,0.171,0.498,0.0494,2.39,0.0166,0.0184,0.516,"0/+","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["OBI1","Cladribine",0.356,0.0805,-0.433,0.0937,-2.39,0.0168,0.0185,0.516,"0/0","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["SP110","Givinostat",0.122,0.56,-0.544,0.0294,-2.09,0.0362,0.0361,0.516,"0/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC10","Differentiating.epigenetic modifier"]
["ZNF595","VER_155008",-0.284,0.168,0.46,0.0733,2.26,0.0241,0.0242,0.516,"0/0","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["TRAPPC10","Dactinomycin",-0.221,0.289,0.511,0.0433,2.25,0.0243,0.0244,0.516,"0/+","RNA and DNA synthesis inhibitor","DNA","Conv.Chemo"]
["ZFP1","NVP_BGT226",0.35,0.0867,-0.398,0.126,-2.25,0.0245,0.0246,0.516,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CG;MTOR","Kinase inhibitor"]
["BZW1","Gemcitabine",0.49,0.013,-0.156,0.565,-1.98,0.0477,0.0455,0.517,"+/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["DONSON","Raltitrexed",0.446,0.0256,-0.316,0.233,-2.31,0.0211,0.0232,0.517,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["DBNL","A_1331852",0.626,0.000815,-0.0701,0.796,-2.3,0.0214,0.0234,0.517,"+/0","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2;MCL1","Apoptotic modulator"]
["GTF2E2","Cladribine",0.357,0.0802,-0.393,0.132,-2.25,0.0242,0.0255,0.517,"0/0","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["MBD2","Ganetespib",-0.252,0.223,0.526,0.0366,2.41,0.0161,0.0174,0.517,"0/+","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["PHKB","Cytarabine",-0.478,0.0156,0.305,0.25,2.39,0.0168,0.0186,0.517,"-/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["SIN3A","PAC_1",-0.308,0.134,0.391,0.135,2.09,0.0367,0.0365,0.517,"0/0","procaspase-3 activator","CASP3","Apoptotic modulator"]
["TMEM63A","Tosedostat",0.16,0.444,-0.514,0.0417,-2.09,0.037,0.0368,0.517,"0/-","Aminopeptidase inhibitor","ANPEP","Protease.proteasome inhibitor"]
["UBFD1","Losmapimod",-0.0339,0.872,0.636,8.09E-3,2.24,0.0248,0.0248,0.517,"0/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["BLVRB","BMS_754807",0.0894,0.671,-0.539,0.0313,-1.98,0.0479,0.0458,0.518,"0/-","IGF1R inhibitor","IGF1R","Kinase inhibitor"]
["ABHD6","Mercaptopurine",-0.426,0.0337,0.232,0.387,1.98,0.0481,0.0459,0.518,"-/0","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["ARID2","Cabazitaxel",0.289,0.162,-0.374,0.153,-1.97,0.0483,0.0461,0.518,"0/0","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["C9orf85","Afuresertib",0.161,0.442,0.692,2.96E-3,1.97,0.0486,0.0463,0.518,"0/+","AKT1-selective inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["DCAF5","Mitomycin_C",-0.0424,0.84,0.642,0.00734,2.3,0.0216,0.0236,0.518,"0/+","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["CCP110","Imiquimod",0.0731,0.729,0.705,0.00229,2.3,0.0216,0.0236,0.518,"0/+","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["L3HYPDH","Losmapimod",-0.3,0.145,0.486,0.0564,2.4,0.0163,0.0176,0.518,"0/0","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["TEX264","Duvelisib",-0.382,0.0596,0.316,0.233,2.09,0.037,0.0369,0.518,"0/0","PI3K inhibitor","PIK3CD","Kinase inhibitor"]
["SERPINH1","Selumetinib",-0.214,0.305,0.472,0.0651,2.08,0.0371,0.037,0.518,"0/0","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["UBTD2","Doxorubicin",-0.158,0.452,0.554,0.0259,2.24,0.0251,0.0252,0.518,"0/+","Topoisomerase II inhibitor","TOP2A;NOLC1","Conv.Chemo"]
["ZC3H8","Cytarabine",0.419,0.0373,-0.324,0.221,-2.24,0.0254,0.0254,0.518,"+/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["ALDH4A1","BX_912",-0.203,0.329,0.448,0.0815,1.97,0.0489,0.0466,0.519,"0/0","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["ACTB","Fludarabine",0.316,0.123,-0.346,0.189,-1.97,0.049,0.0467,0.519,"0/0","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["CASP8","BMS863233",-0.0383,0.856,0.571,0.0208,1.97,0.0493,0.047,0.519,"0/+","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["ATF6","UCN_01",0.3,0.145,-0.361,0.169,-1.97,0.0494,0.0471,0.519,"0/0","PKCbeta, PDK1, Chk, Cdk2 inhibitor","PRKCB;PDPK1","Kinase inhibitor"]
["DPH5","Pazopanib",0.385,0.0576,-0.378,0.149,-2.29,0.0218,0.0238,0.519,"0/0","VEGFR inhibitor","FLT1;KDR;FLT4;KIT;PDGFRA;PDGFRB;CSF1R;FGFR3;ITK","Kinase inhibitor"]
["HS1BP3","Everolimus",-0.212,0.309,0.516,0.0406,2.25,0.0246,0.0259,0.519,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["HSPA8","Tamatinib",0.276,0.182,-0.464,0.07,-2.25,0.0247,0.026,0.519,"0/0","SYK inhibitor","SYK","Kinase inhibitor"]
["GSE1","Tasquinimod",0.265,0.2,-0.472,0.065,-2.24,0.025,0.0263,0.519,"0/0","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["PISD","Dactinomycin",0.238,0.252,-0.531,0.0344,-2.38,0.0171,0.0189,0.519,"0/-","RNA and DNA synthesis inhibitor","DNA","Conv.Chemo"]
["PTPN22","Bryostatin_1",0.383,0.0586,-0.443,0.0859,-2.51,0.0119,0.0137,0.519,"0/0","PKC activator","PRKCE;PRKCA;PRKCE;PRKD1;CASP8","Kinase inhibitor"]
["RPS27","Thioguanine",0.529,6.6E-3,-0.281,0.292,-2.51,0.0122,0.014,0.519,"+/0","Antimetabolite, Purine analog","DNMT1","Conv.Chemo"]
["SNW1","Mercaptopurine",0.499,0.0111,-0.178,0.509,-2.08,0.0374,0.0372,0.519,"+/0","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["SLC5A6","Ixazomib",0.359,0.0783,-0.339,0.199,-2.08,0.0374,0.0372,0.519,"0/0","20S proteasome inhibitor","PSMB5","Protease.proteasome inhibitor"]
["ZMYM3","AZD6738",-0.415,0.0389,0.326,0.217,2.23,0.0256,0.0255,0.519,"-/0","ATR inihibitor","ATR","Kinase inhibitor"]
["ABITRAM","ARV_825",-0.45,0.024,0.199,0.46,1.96,0.0497,0.0474,0.52,"-/0","BET-targeting PROTAC","BRD4","Differentiating.epigenetic modifier"]
["BTF3L4","Mercaptopurine",-0.397,0.0496,0.26,0.33,1.96,0.0498,0.0475,0.52,"-/0","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["DALRD3","Salinomycin",-0.337,0.099,0.422,0.103,2.29,0.0219,0.024,0.52,"0/0","Ionophore","ABCB1","Other"]
["ELF1","Ipatasertib",-0.291,0.158,0.449,0.0807,2.24,0.025,0.0263,0.52,"0/0","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["HECTD3","LY3023414",-0.437,0.0288,0.305,0.251,2.24,0.0251,0.0264,0.52,"-/0","PI3K, mTOR, DNA-PK inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;PRKDC","Kinase inhibitor"]
["KDM1B","Gemcitabine",0.295,0.152,-0.489,0.0548,-2.4,0.0166,0.0179,0.52,"0/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["PNKP","Mitoxantrone",0.132,0.53,-0.604,0.0132,-2.38,0.0174,0.0192,0.52,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["SNX8","Buparlisib",-0.409,0.0424,0.284,0.286,2.08,0.0377,0.0376,0.52,"-/0","PI3K inhibitor, pan-class I","PIK3CA;PIK3CB;PIK3CG;PIK3CD;MTOR;PIK3C3","Kinase inhibitor"]
["TANGO2","Filanesib",-0.643,0.000526,-0.037,0.892,2.08,0.0379,0.0377,0.52,"-/0","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["STARD3NL","8_amino_adenosine",-0.471,0.0176,0.211,0.433,2.07,0.0382,0.038,0.52,"-/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["SPOUT1","Pomalidomide",-0.192,0.357,-0.725,1.47E-3,-2.07,0.0384,0.0382,0.52,"0/-","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["TXLNA","Vorinostat",0.361,0.0766,-0.381,0.145,-2.23,0.026,0.0259,0.52,"0/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["DYNC1H1","Axitinib",-0.042,0.842,0.64,0.00761,2.29,0.0222,0.0243,0.521,"0/+","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["CDC23","Pexidartinib",0.278,0.178,-0.472,0.0647,-2.28,0.0224,0.0245,0.521,"0/0","KIT, CSF1R, FLT3 inhibitor","CSF1R;FLT3;KIT","Kinase inhibitor"]
["HNRNPDL","Vinorelbine",0.378,0.0627,-0.366,0.163,-2.23,0.0256,0.0269,0.521,"0/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["IQGAP3","Taladegib",0.251,0.226,-0.523,0.0378,-2.39,0.0168,0.0181,0.521,"0/-","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["IBTK","BI_2536",0.221,0.288,-0.545,0.0291,-2.39,0.0169,0.0183,0.521,"0/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["MND1","8_amino_adenosine",0.477,0.016,-0.305,0.25,-2.38,0.0171,0.0185,0.521,"+/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["ORAI1","ZSTK474",-0.437,0.0291,0.347,0.188,2.37,0.0177,0.0194,0.521,"-/0","PI3K gamma selective inhibitor","PIK3CG","Kinase inhibitor"]
["POLR2L","Seliciclib",-0.357,0.0802,0.461,0.072,2.49,0.0127,0.0145,0.521,"0/0","CDK2, 7, 9 inhibitor","CDK2;CDK1;CDK5;MAPK1;MAPK3","Kinase inhibitor"]
["RNFT1","AMG_925",0.441,0.0274,-0.379,0.148,-2.49,0.0127,0.0145,0.521,"+/0","FLT3, CDK4 inhibitor","FLT3;CDK4","Kinase inhibitor"]
["TEDC2","PFI_1",0.466,0.0189,-0.214,0.426,-2.07,0.0388,0.0386,0.521,"+/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["ZNF518A","Doxorubicin",0.314,0.127,-0.424,0.102,-2.22,0.0264,0.0263,0.521,"0/0","Topoisomerase II inhibitor","TOP2A;NOLC1","Conv.Chemo"]
["CSTF2","RO5126766",-0.429,0.0323,0.327,0.217,2.28,0.0225,0.0246,0.522,"-/0","dual RAF and MEK inhibitor","RAF1;BRAF;MAP2K1;MAP2K2","Kinase inhibitor"]
["HSF2","Sabutoclax",0.368,0.0701,-0.374,0.153,-2.23,0.0258,0.0271,0.522,"0/0","pan Bcl-2 family inhibitor","BCL2;BCL2L1;MCL1;BCL2A1","Apoptotic modulator"]
["MAGED1","Daunorubicin",0.353,0.0832,-0.432,0.0945,-2.38,0.0174,0.0187,0.522,"0/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["PIP4K2B","OSU_03012",-0.468,0.0184,0.311,0.241,2.37,0.0178,0.0196,0.522,"-/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["NPC1","AZD7762",-0.225,0.279,0.536,0.0324,2.37,0.018,0.0198,0.522,"0/+","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["SLC38A5","Belinostat",-0.0393,0.852,-0.642,0.00732,-2.07,0.0389,0.0386,0.522,"0/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["SSR3","Mocetinostat",-0.61,0.0012,0.0124,0.964,2.06,0.0391,0.0389,0.522,"-/0","HDAC inhibitor (HDAC1 and 2-selective)","HDAC1;HDAC2;HDAC3;HDAC11","Differentiating.epigenetic modifier"]
["USP3","Navitoclax",-0.268,0.196,0.463,0.0709,2.22,0.0266,0.0265,0.522,"0/0","Bcl-2,Bcl-XL inhibitor","BCL2;BCL2L2;BAD;BCL2L1;MCL1","Apoptotic modulator"]
["DNAJC7","PF_06463922",0.266,0.199,-0.481,0.059,-2.28,0.0227,0.0248,0.523,"0/0","ALK, ROS1 inhibitor","ALK;LTK;FER;FES;PTK2B;TNK2;PTK2;NTRK1;NTRK2;NTRK3;FRK;ROS1","Kinase inhibitor"]
["FAM161A","BMS_911543",-0.304,0.14,0.435,0.0925,2.23,0.0259,0.0272,0.523,"0/0","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["KCNAB2","Vinorelbine",-0.345,0.0908,0.437,0.0903,2.37,0.0178,0.0191,0.523,"0/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["PRDX5","Gemcitabine",-0.452,0.0233,0.366,0.164,2.49,0.0128,0.0146,0.523,"-/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["RAB3GAP1","GSK_2334470",0.0342,0.871,0.719,0.00171,2.49,0.0128,0.0147,0.523,"0/+","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["TNKS1BP1","Doxorubicin",0.0462,0.826,-0.588,0.0167,-2.06,0.0395,0.0392,0.523,"0/-","Topoisomerase II inhibitor","TOP2A;NOLC1","Conv.Chemo"]
["VPS51","PD0325901",0.0579,0.783,-0.615,0.0113,-2.21,0.0269,0.0268,0.523,"0/-","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["DDX19A","8_chloro_adenosine",0.268,0.194,-0.479,0.0608,-2.28,0.0228,0.0249,0.524,"0/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["FMNL3","Ivosidenib",-0.171,0.415,0.541,0.0304,2.22,0.0261,0.0274,0.524,"0/+","IDH1 R132H and R132C inhibitor","IDH1","Differentiating.epigenetic modifier"]
["MRPL1","Quizartinib",0.39,0.054,-0.394,0.131,-2.37,0.0179,0.0192,0.524,"0/0","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["NASP","Avadomide_CC122",0.324,0.114,-0.454,0.0772,-2.36,0.0182,0.02,0.524,"0/0","IMiD immunomodulator","CRBN","Immunomodulatory"]
["RNF130","GSK_2334470",0.359,0.0778,-0.457,0.0752,-2.48,0.013,0.0148,0.524,"0/0","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["RCN1","Crenolanib",0.0257,0.903,-0.687,3.29E-3,-2.48,0.0131,0.0149,0.524,"0/-","PDGFRA and PDGFRB inhibitor","PDGFRA","Kinase inhibitor"]
["TAF6L","A_1155463",0.509,0.00933,-0.156,0.565,-2.05,0.04,0.0397,0.524,"+/0","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2","Apoptotic modulator"]
["TMC6","Tivantinib",-0.219,0.293,0.459,0.074,2.05,0.0401,0.0397,0.524,"0/0","MET inhibitor","MET","Kinase inhibitor"]
["ZNF792","8_amino_adenosine",-0.201,0.334,0.514,0.0415,2.21,0.0272,0.027,0.524,"0/+","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["ZNF330","Bafetinib",-0.509,0.0094,0.208,0.439,2.21,0.0273,0.0272,0.524,"-/0","ABL, Lyn inhibitor","ABL1;LYN","Kinase inhibitor"]
["FBXO28","PFI_1",0.486,0.0139,-0.242,0.366,-2.22,0.0263,0.0276,0.525,"+/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["GRIPAP1","RGFP966",-0.449,0.0245,0.285,0.284,2.22,0.0265,0.0278,0.525,"-/0","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["KHDRBS1","SN_38",0.488,0.0134,-0.285,0.285,-2.36,0.0182,0.0195,0.525,"+/0","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["PIGS","Decitabine",-0.309,0.133,0.465,0.0693,2.36,0.0185,0.0203,0.525,"0/0","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["SMCR8","Galiellalactone",0.336,0.101,-0.352,0.182,-2.05,0.0404,0.0401,0.525,"0/0","STAT3-DNA interaction inhibitor","STAT3","Other"]
["ST3GAL2","ABT_751",0.397,0.0492,-0.288,0.28,-2.05,0.0406,0.0402,0.525,"+/0","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["SFMBT2","Sotrastaurin",-0.213,0.308,0.462,0.0715,2.05,0.0407,0.0404,0.525,"0/0","PKC inhibitor","PRKCB;PRKCQ;PRKCH;PRKCA;PRKCE;PRKCA","Kinase inhibitor"]
["SOD1","Romidepsin",0.0188,0.929,0.625,0.00957,2.04,0.041,0.0406,0.525,"0/+","HDAC inhibitor","HDAC1;HDAC2","Differentiating.epigenetic modifier"]
["YWHAZ","Quizartinib",-0.2,0.338,0.514,0.0418,2.2,0.0276,0.0275,0.525,"0/+","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["TSPYL2","CC_115",0.0545,0.796,-0.614,0.0113,-2.2,0.0276,0.0275,0.525,"0/-","mTOR, DNA-PK inhibitor","MTOR;PIK3CA;PRKDC","Kinase inhibitor"]
["GLTP","Agerafenib_CEP_32496",-0.318,0.121,0.419,0.106,2.22,0.0266,0.0279,0.526,"0/0","BRAF(V600E) inhibitor","BRAF;RAF1;KIT;RET;LCK;ABL1;PDGFRB;CSF1R;MET;EGFR;KDR;EPHA2","Kinase inhibitor"]
["KCTD1","Marimastat",0.0499,0.813,-0.65,0.00644,-2.36,0.0184,0.0197,0.526,"0/-","MMP-9, MMP-1, MMP-2, MMP-14, MMP-7 inhibitor","MMP1;MMP2;MMP9;MMP7;MMP14","Other"]
["JADE2","SN_38",-0.127,0.545,0.602,0.0135,2.36,0.0184,0.0198,0.526,"0/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["POLR2D","MST_312",0.315,0.125,-0.493,0.0521,-2.48,0.0133,0.0151,0.526,"0/0","Telomerase inhibitor","TERT","Other"]
["TMEM214","LY3023414",0.0807,0.701,0.661,0.00527,2.04,0.0412,0.0408,0.526,"0/+","PI3K, mTOR, DNA-PK inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;PRKDC","Kinase inhibitor"]
["SNRPE","Enzalutamide",0.00502,0.981,0.616,0.0111,2.04,0.0414,0.041,0.526,"0/+","AR antagonist","AR","Hormone therapy"]
["ZNRF2","AZD1208",0.168,0.423,-0.537,0.0319,-2.2,0.0278,0.0276,0.526,"0/-","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["CDK2AP1","Sitravatinib",-0.698,0.000104,-0.0713,0.793,2.27,0.0235,0.0256,0.527,"-/0","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["CCDC9","ENMD_2076",-0.303,0.141,0.445,0.0839,2.26,0.0236,0.0258,0.527,"0/0","pan-Aurora, VEGFR inhibitor","AURKA;FLT3;RET;FLT4;SRC;CSF1R;NTRK1;PDGFRA;BLK;KDR;YES1;FYN;AURKB;PTK2;FGFR2;FGFR1;JAK2;KIT;ABL1","Kinase inhibitor"]
["HSD17B8","Ibrutinib",-0.345,0.0914,0.393,0.132,2.22,0.0268,0.0281,0.527,"0/0","BTK inhibitor","BTK;BLK;EGFR;FYN;LYN;LCK;BRAF;WNK1","Kinase inhibitor"]
["GTF2H4","Trifluridine",-0.385,0.0577,0.353,0.18,2.21,0.027,0.0283,0.527,"0/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["HSD17B12","Vinorelbine",0.284,0.168,-0.447,0.0828,-2.21,0.0271,0.0285,0.527,"0/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["MFSD10","Dabrafenib",0.0363,0.863,0.696,0.00274,2.35,0.0186,0.0199,0.527,"0/+","BRAF(V600E) inhibitor","BRAF;RAF1","Kinase inhibitor"]
["NDUFS7","Thioguanine",-0.364,0.0738,0.414,0.111,2.35,0.0189,0.0207,0.527,"0/0","Antimetabolite, Purine analog","DNMT1","Conv.Chemo"]
["MSRB2","Etoposide",-0.489,0.0132,0.279,0.295,2.35,0.0189,0.0207,0.527,"-/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["SCYL3","Amsacrine",0.357,0.0795,-0.454,0.0773,-2.47,0.0136,0.0154,0.527,"0/0","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["TCHP","Deferoxamine",0.276,0.182,-0.405,0.12,-2.04,0.0415,0.0411,0.527,"0/0","Iron chelator","APP","Other"]
["SLC16A3","Tacrolimus",-0.102,0.629,0.544,0.0292,2.04,0.0417,0.0413,0.527,"0/+","binds FKBP12, causes inhibition of calcineurin","FKBP1A","Rapalog"]
["ZNF234","Crenolanib",0.428,0.0326,-0.301,0.258,-2.2,0.0281,0.0279,0.527,"+/0","PDGFRA and PDGFRB inhibitor","PDGFRA","Kinase inhibitor"]
["ZNF516","Imatinib",0.0274,0.896,-0.629,0.00908,-2.19,0.0284,0.0282,0.527,"0/-","ABL, Kit, PDGFRB inhibitor","ABL1","Kinase inhibitor"]
["FAM133B","RGFP966",0.317,0.123,-0.417,0.108,-2.21,0.0272,0.0286,0.528,"0/0","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["GRWD1","GSK650394",0.366,0.0716,-0.369,0.159,-2.21,0.0274,0.0287,0.528,"0/0","SGK1 and 2 inhibitor","SGK1","Kinase inhibitor"]
["FDFT1","Ribociclib",0.339,0.0977,-0.395,0.13,-2.2,0.0276,0.0289,0.528,"0/0","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["KIAA1217","Litronesib",0.119,0.57,-0.605,0.0131,-2.35,0.019,0.0204,0.528,"0/-","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["IQSEC1","Sirolimus",0.456,0.0219,-0.315,0.235,-2.34,0.0192,0.0206,0.528,"+/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["POLR3E","Daporinad",0.426,0.0337,-0.385,0.141,-2.46,0.0139,0.0158,0.528,"+/0","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["SREBF1","Ivosidenib",-0.394,0.0513,0.287,0.281,2.03,0.0419,0.0415,0.528,"0/0","IDH1 R132H and R132C inhibitor","IDH1","Differentiating.epigenetic modifier"]
["SUB1","Ganetespib",-0.501,0.0107,0.159,0.557,2.03,0.0421,0.0417,0.528,"-/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["GFM2","Merestinib",0.377,0.0631,-0.357,0.175,-2.2,0.0277,0.029,0.529,"0/0","MET inhibitor","MET","Kinase inhibitor"]
["LCLAT1","Belinostat",-0.396,0.05,0.379,0.147,2.34,0.0193,0.0207,0.529,"-/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["IRF2BP2","Tozasertib",0.352,0.0847,-0.422,0.103,-2.34,0.0194,0.0208,0.529,"0/0","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["PHRF1","Clofarabine",0.502,0.0105,-0.259,0.333,-2.34,0.0195,0.0213,0.529,"+/0","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["SEMA4A","Everolimus",-0.229,0.271,0.555,0.0257,2.45,0.0141,0.016,0.529,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SNX18","Cabazitaxel",-0.358,0.079,0.324,0.221,2.03,0.0423,0.0419,0.529,"0/0","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["TDP2","Temsirolimus",0.335,0.101,-0.346,0.19,-2.03,0.0426,0.0422,0.529,"0/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["U2AF2","Vismodegib",-0.219,0.292,0.495,0.0515,2.19,0.0288,0.0286,0.529,"0/0","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["ZNF22","GSK2636771",-0.0787,0.709,0.595,0.015,2.18,0.0289,0.0287,0.529,"0/+","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["WDR62","Vinorelbine",0.527,0.00684,-0.176,0.514,-2.18,0.0291,0.0289,0.529,"+/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["DCAF11","Fimepinostat_CUDC_907",-0.000251,0.999,-0.657,5.64E-3,-2.25,0.0243,0.0264,0.53,"0/-","HDAC1, 2, 3, 10  and 11, PI3Kalpha inhibitor","HDAC1;HDAC2;HDAC3;HDAC10;HDAC11;PIK3CA","Differentiating.epigenetic modifier"]
["CHM","Venetoclax",0.369,0.0695,-0.38,0.146,-2.25,0.0244,0.0265,0.53,"0/0","Bcl-2 selective inhibitor","BCL2","Apoptotic modulator"]
["MID1","8_amino_adenosine",0.338,0.0989,-0.435,0.0924,-2.34,0.0195,0.0209,0.53,"0/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["MMP24OS","Daporinad",-0.233,0.263,0.521,0.0384,2.33,0.0198,0.0211,0.53,"0/+","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["LRRCC1","Filanesib",0.347,0.0888,-0.424,0.102,-2.33,0.0199,0.0212,0.53,"0/0","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["RUBCNL","Copanlisib",0.296,0.15,-0.503,0.0472,-2.45,0.0141,0.016,0.53,"0/-","PI3K alpha, delta selective inhibitor","PIK3CA;PIK3CB;PIK3CG;PIK3CD","Kinase inhibitor"]
["TAF10","AMG_925",-0.423,0.035,0.251,0.349,2.02,0.043,0.0425,0.53,"-/0","FLT3, CDK4 inhibitor","FLT3;CDK4","Kinase inhibitor"]
["SRGN","SGC_CBP30",0.0476,0.821,0.638,0.0078,2.02,0.0431,0.0426,0.53,"0/+","CREBBP, EP300 bromodomain inhibitor","CREBBP","Differentiating.epigenetic modifier"]
["SERGEF","UNC0638",-0.0466,0.825,0.578,0.019,2.02,0.0434,0.0429,0.53,"0/+","G9a, GLP inhibitor","EHMT2","Differentiating.epigenetic modifier"]
["UXS1","Talazoparib",0.574,0.00272,-0.108,0.69,-2.18,0.0294,0.0292,0.53,"+/0","PARP1 and 2 inhibitor","PARP1;PARP2","Differentiating.epigenetic modifier"]
["CLUAP1","Acitretin",0.146,0.485,-0.564,0.0228,-2.25,0.0246,0.0267,0.531,"0/-","Retinoic acid receptor agonist","RARA;RARB;RXRA;RXRB;RXRG","Differentiating.epigenetic modifier"]
["GSTP1","BIIB021",0.294,0.154,-0.435,0.0926,-2.2,0.0281,0.0295,0.531,"0/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["HPS1","PF_06463922",0.0194,0.927,0.656,5.79E-3,2.19,0.0285,0.0298,0.531,"0/+","ALK, ROS1 inhibitor","ALK;LTK;FER;FES;PTK2B;TNK2;PTK2;NTRK1;NTRK2;NTRK3;FRK;ROS1","Kinase inhibitor"]
["GNA15","GSK2636771",-0.153,0.464,0.545,0.029,2.19,0.0285,0.0298,0.531,"0/+","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["MAN2B2","SGC_CBP30",0.349,0.0876,-0.421,0.105,-2.32,0.0202,0.0215,0.531,"0/0","CREBBP, EP300 bromodomain inhibitor","CREBBP","Differentiating.epigenetic modifier"]
["PDRG1","Amsacrine",-0.167,0.424,-0.755,0.000724,-2.33,0.0198,0.0216,0.531,"0/-","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["NCBP3","CCT196969",-0.0521,0.804,-0.7,0.00254,-2.33,0.0198,0.0216,0.531,"0/-","pan-RAF, Src inhibitor","RAF1;BRAF;SRC;LCK","Kinase inhibitor"]
["PDE3B","Rocilinostat",-0.199,0.34,0.545,0.0291,2.32,0.0201,0.0219,0.531,"0/+","HDAC6 selective inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["MSTO1","NMS_873",-0.172,0.412,0.563,0.023,2.32,0.0204,0.0222,0.531,"0/+","p97, VCP inhibitor","VCP","Other"]
["PNPLA8","Docetaxel",-0.416,0.0384,0.352,0.182,2.32,0.0205,0.0223,0.531,"-/0","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["PPAT","Mercaptopurine",0.207,0.321,-0.569,0.0213,-2.45,0.0143,0.0163,0.531,"0/-","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["RNF220","AZD7762",0.699,1.02E-4,0.0105,0.969,-2.44,0.0146,0.0165,0.531,"+/0","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["PPP1CA","AT_406",0.13,0.536,0.755,0.000724,2.44,0.0147,0.0166,0.531,"0/+","XIAP, cIAP1, cIAP2 inhibitor","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["PROM1","AZD_5363",-0.0791,0.707,0.648,0.00658,2.44,0.0149,0.0168,0.531,"0/+","AKT inhibitor","AKT1;AKT2;AKT3;ROCK2","Kinase inhibitor"]
["RRAS2","Erdafitinib",-0.221,0.288,0.555,0.0255,2.43,0.015,0.017,0.531,"0/+","FGFR inhibitor","FGFR1;FGFR2;FGFR3;FGFR4","Kinase inhibitor"]
["SPEN","WEHI_539",-0.237,0.254,0.433,0.0935,2.02,0.0437,0.0432,0.531,"0/0","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["WDR91","Danusertib",-0.416,0.0387,0.307,0.247,2.17,0.0298,0.0295,0.531,"-/0","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["CDC16","ABT_751",0.495,0.0118,-0.238,0.375,-2.25,0.0248,0.0269,0.532,"+/0","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["FBLL1","Idelalisib",0.237,0.253,-0.481,0.0596,-2.19,0.0286,0.03,0.532,"0/0","PI3K inhibitor, p110-selective","PIK3CD","Kinase inhibitor"]
["HNRNPL","Danusertib",0.257,0.214,-0.463,0.0708,-2.19,0.0288,0.0302,0.532,"0/0","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["MAP7D1","Vandetanib",-0.44,0.0276,0.326,0.217,2.32,0.0204,0.0217,0.532,"-/0","VEGFR, EGFR, RET inhibitor","KDR;FLT4;EGFR;RET","Kinase inhibitor"]
["MPG","AT9283",-0.401,0.047,0.367,0.162,2.32,0.0206,0.0219,0.532,"-/0","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["RSL24D1","PF_03758309",0.245,0.237,-0.537,0.0319,-2.43,0.015,0.017,0.532,"0/-","PAK4 inhibitor","PAK4","Kinase inhibitor"]
["STRIP1","VE_821",-0.319,0.12,0.357,0.174,2.01,0.0439,0.0434,0.532,"0/0","ATR inihibitor","ATR","Kinase inhibitor"]
["TMEM160","CCT196969",0.249,0.229,-0.421,0.104,-2.01,0.0442,0.0437,0.532,"0/0","pan-RAF, Src inhibitor","RAF1;BRAF;SRC;LCK","Kinase inhibitor"]
["ZNRD2","GSK_2334470",0.446,0.0256,-0.273,0.306,-2.17,0.03,0.0297,0.532,"+/0","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["CHML","RGFP966",0.361,0.0766,-0.386,0.14,-2.24,0.025,0.0271,0.533,"0/0","HDAC3 inhibitor","HDAC3","Differentiating.epigenetic modifier"]
["ENDOG","AT_406",-0.575,2.66E-3,0.109,0.687,2.18,0.0289,0.0303,0.533,"-/0","XIAP, cIAP1, cIAP2 inhibitor","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["HSP90AB1","WEHI_539",-0.554,0.00405,0.138,0.61,2.18,0.0291,0.0304,0.533,"-/0","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["GON4L","Filanesib",-0.222,0.287,0.491,0.0537,2.18,0.0293,0.0307,0.533,"0/0","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["LRIF1","Eribulin",0.308,0.134,-0.454,0.0773,-2.31,0.0208,0.0221,0.533,"0/0","Mitotic inhibitor, microtubule depolymerizer","TUBB1","Conv.Chemo"]
["PHPT1","Pictilisib",-0.421,0.0363,0.344,0.192,2.31,0.021,0.0228,0.533,"-/0","PI3K inhibitor, pan-class I","PIK3CA;PIK3CB;PIK3CG;PIK3CD;MTOR","Kinase inhibitor"]
["PUDP","Mocetinostat",-0.169,0.418,0.59,0.0161,2.43,0.0152,0.0172,0.533,"0/+","HDAC inhibitor (HDAC1 and 2-selective)","HDAC1;HDAC2;HDAC3;HDAC11","Differentiating.epigenetic modifier"]
["PPP1R18","NMS_873",0.189,0.365,-0.576,0.0194,-2.43,0.0153,0.0173,0.533,"0/-","p97, VCP inhibitor","VCP","Other"]
["S100A6","Midostaurin",-0.142,0.499,0.607,0.0127,2.42,0.0155,0.0175,0.533,"0/+","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["SCLT1","MK_2206",-0.0298,0.888,0.673,0.00429,2.42,0.0156,0.0176,0.533,"0/+","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["PPP2R3C","Talazoparib",0.527,0.00683,-0.253,0.344,-2.41,0.0158,0.0178,0.533,"+/0","PARP1 and 2 inhibitor","PARP1;PARP2","Differentiating.epigenetic modifier"]
["RPL18","BI_2536",0.305,0.138,-0.484,0.0578,-2.41,0.016,0.018,0.533,"0/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["SYF2","Tubacin",0.47,0.0178,-0.191,0.479,-2.01,0.0445,0.0439,0.533,"+/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["TIPIN","BAY_87_2243",-0.0618,0.769,0.566,0.0224,2.01,0.0445,0.044,0.533,"0/+","HIF1alpha inhibitor","HIF1A","Differentiating.epigenetic modifier"]
["TRIP10","Sorafenib",0.314,0.126,-0.408,0.117,-2.17,0.0302,0.0299,0.533,"0/0","BRAF, FGFR-1, VEGFR-2 and -3, PDGFR-beta, KIT, and FLT3 inhibitor","BRAF;FGFR1;KDR;FLT3;KIT;FLT4;PDGFRB","Kinase inhibitor"]
["ZBTB7A","Marimastat",0.365,0.0726,-0.358,0.174,-2.16,0.0304,0.0302,0.533,"0/0","MMP-9, MMP-1, MMP-2, MMP-14, MMP-7 inhibitor","MMP1;MMP2;MMP9;MMP7;MMP14","Other"]
["ZNF213","Erlotinib",-0.0671,0.75,0.597,0.0145,2.16,0.0306,0.0303,0.533,"0/+","EGFR inhibitor","EGFR","Kinase inhibitor"]
["CYBB","Deferoxamine",-0.388,0.0553,0.357,0.175,2.24,0.0252,0.0274,0.534,"0/0","Iron chelator","APP","Other"]
["EDEM1","BMS863233",0.38,0.0607,-0.364,0.166,-2.23,0.0255,0.0276,0.534,"0/0","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["CDK1","Nilotinib",0.344,0.0923,-0.399,0.126,-2.23,0.0256,0.0277,0.534,"0/0","ABL inhibitor","ABL1;KIT","Kinase inhibitor"]
["HSPE1","Cytarabine",0.335,0.101,-0.391,0.134,-2.18,0.0295,0.0308,0.534,"0/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["EIF4G1","PF_670462",0.176,0.4,-0.525,0.0368,-2.17,0.0296,0.0309,0.534,"0/-","CK1epsilon and CK1delta inhibitor","CSNK1D;CSNK1E","Kinase inhibitor"]
["MAP7","Doramapimod",0.523,0.00727,-0.223,0.407,-2.31,0.021,0.0223,0.534,"+/0","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["PLS1","Clofarabine",-0.178,0.395,-0.756,0.00071,-2.3,0.0212,0.0229,0.534,"0/-","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["RPGR","Palomid_529",-0.112,0.595,0.621,0.0102,2.4,0.0165,0.0184,0.534,"0/+","AKT, MTOR, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3;MTOR","Kinase inhibitor"]
["TMED4","Azacitidine",-0.0219,0.917,0.591,0.0159,2.01,0.0449,0.0443,0.534,"0/+","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["SRSF5","OTS167",0.0214,0.919,-0.591,0.016,-2,0.0453,0.0447,0.534,"0/-","MELK inhibitor","MELK","Kinase inhibitor"]
["ZNF330","NVP_RAF265",-0.516,0.00828,0.182,0.5,2.16,0.031,0.0306,0.534,"-/0","C-Raf inhibitor, unclear MoA","RAF1;BRAF;KDR","Kinase inhibitor"]
["ZNF485","Molibresib",0.424,0.0347,-0.293,0.271,-2.16,0.0311,0.0307,0.534,"+/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["CENPN","Pomalidomide",-0.166,0.429,0.545,0.0289,2.23,0.026,0.0281,0.535,"0/+","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["ENSA","IOX_1",-0.308,0.134,0.413,0.111,2.17,0.0301,0.0314,0.535,"0/0","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["MCM3","Daunorubicin",0.126,0.548,-0.591,0.0159,-2.3,0.0212,0.0225,0.535,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["NMT1","Altiratinib",0.429,0.0322,-0.333,0.208,-2.3,0.0213,0.0231,0.535,"+/0","MET, Tie-2 inhibitor","MET;NTRK1;NTRK3;NTRK2;TEK;FLT3;KIT;KDR","Kinase inhibitor"]
["RABEP1","Pomalidomide",-0.172,0.41,0.581,0.0182,2.4,0.0165,0.0186,0.535,"0/+","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["RHOA","Milciclib",-0.182,0.385,0.575,0.0199,2.39,0.0166,0.0186,0.535,"0/+","CDK2 inhibitor","CDK2;CDK4;CDK5;CDK7;NTRK1","Kinase inhibitor"]
["SCCPDH","Cabozantinib",-0.522,0.00738,0.251,0.348,2.39,0.0168,0.0188,0.535,"-/0","VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor","KDR;MET;FLT3;KIT;RET;TEK","Kinase inhibitor"]
["PTPRF","Tivozanib",-0.14,0.504,0.6,0.0141,2.38,0.0172,0.0192,0.535,"0/+","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["TBC1D5","Sapanisertib",-0.366,0.0721,0.306,0.249,2,0.0455,0.0448,0.535,"0/0","mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["ZFAND6","Vincristine",-0.205,0.325,0.497,0.0502,2.15,0.0313,0.0309,0.535,"0/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB;TUBA4A","Conv.Chemo"]
["ZNF33A","Erastin",0.337,0.0993,-0.381,0.145,-2.15,0.0315,0.0311,0.535,"0/0","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["DVL2","Sorafenib",-0.266,0.199,0.467,0.0684,2.22,0.0261,0.0282,0.536,"0/0","BRAF, FGFR-1, VEGFR-2 and -3, PDGFR-beta, KIT, and FLT3 inhibitor","BRAF;FGFR1;KDR;FLT3;KIT;FLT4;PDGFRB","Kinase inhibitor"]
["EMC4","ARV_825",0.385,0.0575,-0.339,0.2,-2.17,0.0302,0.0315,0.536,"0/0","BET-targeting PROTAC","BRD4","Differentiating.epigenetic modifier"]
["GADD45GIP1","Vinblastine",0.037,0.861,-0.617,0.0109,-2.17,0.0304,0.0317,0.536,"0/-","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["LAS1L","Quizartinib",0.464,0.0193,-0.293,0.271,-2.3,0.0215,0.0228,0.536,"+/0","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["OSBP","Vismodegib",0.219,0.292,-0.523,0.0377,-2.3,0.0216,0.0234,0.536,"0/-","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["RAB30","Alpelisib",0.404,0.045,-0.383,0.143,-2.38,0.0174,0.0193,0.536,"+/0","PI3Kalpha selective inhibitor","PIK3CA","Kinase inhibitor"]
["TEDC2","Omipalisib",0.31,0.132,-0.361,0.169,-2,0.0458,0.0451,0.536,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["TLK1","Onalespib",-0.431,0.0313,0.232,0.386,2,0.0459,0.0453,0.536,"-/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["SLC31A1","MK_2206",-0.0818,0.698,0.548,0.028,1.99,0.0462,0.0455,0.536,"0/+","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["WBP4","Raltitrexed",0.0114,0.957,-0.629,9.11E-3,-2.15,0.0319,0.0315,0.536,"0/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["UBXN1","Aldoxorubicin",0.303,0.141,-0.412,0.113,-2.14,0.032,0.0315,0.536,"0/0","Topoisomerase II inhibitor, Albumin binding","TOP2A;TOP2B","Conv.Chemo"]
["EEF1A2","GSK_690693",0.567,0.0031,-0.132,0.627,-2.22,0.0265,0.0287,0.537,"+/0","AKT, PKA, PKC inhibitor","AKT1;AKT2;AKT3;PRKCE;PRKCB;PRKCD;PRKCH;PRKCQ;PRKX;PRKG1","Kinase inhibitor"]
["CD38","Capmatinib",0.0646,0.759,0.686,0.00337,2.22,0.0267,0.0289,0.537,"0/+","MET inhibitor","MET","Kinase inhibitor"]
["GPBP1","Duvelisib",0.373,0.066,-0.349,0.185,-2.16,0.0306,0.0319,0.537,"0/0","PI3K inhibitor","PIK3CD","Kinase inhibitor"]
["GAK","Amsacrine",-0.199,0.339,0.503,0.0471,2.16,0.0308,0.0321,0.537,"0/+","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["MGA","AZD_6482",0.577,0.00254,-0.144,0.596,-2.29,0.0218,0.0232,0.537,"+/0","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["PARPBP","Glesatinib",0.497,0.0116,-0.252,0.347,-2.29,0.0219,0.0237,0.537,"+/0","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["PRKAR1A","Tucidinostat",-0.414,0.0397,0.371,0.157,2.37,0.0176,0.0196,0.537,"-/0","HDAC1, 2, 3 and 10 inhibitor","HDAC1;HDAC2;HDAC3;HDAC10","Differentiating.epigenetic modifier"]
["PTPRA","TAK_901",-0.181,0.386,0.569,0.0214,2.37,0.0178,0.0198,0.537,"0/+","Aurora, Src family, JAK3, RTK inhibitor","AURKA;AURKB;JAK3;SRC;CLK2;FGR;LRRK2;YES1;LCK;FYN;ABL1;AXL;ABL2;HCK;RET;FRK;NTRK1;FGFR2","Kinase inhibitor"]
["SYNRG","Tacedinaline",-0.0211,0.92,-0.616,0.0111,-1.99,0.0463,0.0457,0.537,"0/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["TGDS","Trifluridine",0.322,0.117,-0.347,0.188,-1.99,0.0466,0.0459,0.537,"0/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["SPC24","Tucidinostat",0.46,0.0207,-0.196,0.467,-1.99,0.0468,0.0461,0.537,"+/0","HDAC1, 2, 3 and 10 inhibitor","HDAC1;HDAC2;HDAC3;HDAC10","Differentiating.epigenetic modifier"]
["ZNF518A","Dovitinib",0.0941,0.655,-0.575,0.0198,-2.14,0.0322,0.0318,0.537,"0/-","FGFR inhibitor","FGFR1;FGFR3;KIT;FLT3;FLT4","Kinase inhibitor"]
["CHCHD3","Cladribine",0.0995,0.636,-0.587,0.0168,-2.21,0.0271,0.0293,0.538,"0/-","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["GPRIN1","Dovitinib",-0.141,0.501,0.546,0.0286,2.16,0.0309,0.0322,0.538,"0/+","FGFR inhibitor","FGFR1;FGFR3;KIT;FLT3;FLT4","Kinase inhibitor"]
["IMPA2","Sepantronium_bromide",-0.229,0.272,0.514,0.0415,2.29,0.022,0.0233,0.538,"0/+","Survivin inhibitor","BIRC5","Apoptotic modulator"]
["MAFF","Varlitinib",0.0397,0.851,-0.642,0.00736,-2.29,0.0221,0.0234,0.538,"0/-","EGFR HER2 inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["PAFAH2","AT_406",0.486,0.0137,-0.263,0.325,-2.29,0.0221,0.0239,0.538,"+/0","XIAP, cIAP1, cIAP2 inhibitor","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["NEMP2","Mercaptopurine",-0.458,0.0215,0.296,0.265,2.29,0.0222,0.024,0.538,"-/0","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["NOMO1","Azacitidine",0.44,0.0279,-0.316,0.233,-2.28,0.0223,0.0242,0.538,"+/0","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["SELENOF","OSU_03012",-0.715,{"v":5.94E-5,"d":"5.94E-05"},-0.0706,0.795,2.36,0.0182,0.0202,0.538,"-/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["STX6","Auranofin",-0.107,0.61,0.528,0.0357,1.98,0.0472,0.0465,0.538,"0/+","Antirheumatic agent","PRDX5;IKBKB","Conv.Chemo"]
["TARS3","Birabresib",-0.0722,0.732,0.552,0.0266,1.98,0.0473,0.0466,0.538,"0/+","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["SF3B1","OSU_03012",0.404,0.0452,-0.259,0.333,-1.98,0.0475,0.0468,0.538,"+/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["ZCCHC9","Silmitasertib",0.359,0.0778,-0.355,0.177,-2.14,0.0326,0.0322,0.538,"0/0","CSNK2A1 inhibitor","CSNK2A1","Kinase inhibitor"]
["ZNF333","Tivantinib",0.357,0.0794,-0.357,0.175,-2.14,0.0327,0.0322,0.538,"0/0","MET inhibitor","MET","Kinase inhibitor"]
["DENND11","Auranofin",0.0752,0.721,0.689,3.13E-3,2.21,0.0274,0.0296,0.539,"0/+","Antirheumatic agent","PRDX5;IKBKB","Conv.Chemo"]
["EIF2B5","NVP_RAF265",0.185,0.375,-0.513,0.0423,-2.16,0.0312,0.0324,0.539,"0/-","C-Raf inhibitor, unclear MoA","RAF1;BRAF;KDR","Kinase inhibitor"]
["MFGE8","Tubastatin_A",-0.349,0.0874,0.409,0.115,2.28,0.0224,0.0237,0.539,"0/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["MLXIP","Epacadostat",-0.188,0.368,0.542,0.0299,2.28,0.0225,0.0238,0.539,"0/+","IDO inhibitor","IDO1","Immunomodulatory"]
["KIF14","Perifosine",0.269,0.193,0.791,0.000267,2.28,0.0228,0.0241,0.539,"0/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["POLE3","Sonidegib",-0.249,0.23,0.496,0.0506,2.28,0.0224,0.0242,0.539,"0/0","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["NR2C2","Prexasertib",-0.366,0.072,0.391,0.134,2.28,0.0227,0.0245,0.539,"0/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["OSTM1","Selinexor",-0.338,0.0981,0.417,0.108,2.28,0.0229,0.0247,0.539,"0/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["NSL1","Talazoparib",0.428,0.0329,-0.325,0.219,-2.27,0.0231,0.0248,0.539,"+/0","PARP1 and 2 inhibitor","PARP1;PARP2","Differentiating.epigenetic modifier"]
["PRKAR1A","Regorafenib",0.0241,0.909,0.69,0.00308,2.36,0.0185,0.0205,0.539,"0/+","BRAF, c-Kit, VEGFR2 inhibitor","BRAF;RAF1;KIT;KDR;FLT1;RET;PDGFRB;FLT4","Kinase inhibitor"]
["SNTB2","GSK269962",0.13,0.537,0.676,0.00401,1.98,0.0478,0.0471,0.539,"0/+","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["SLC38A9","AZD_5438",-0.0703,0.739,-0.643,0.00727,-1.98,0.0479,0.0472,0.539,"0/-","CDK1, 2, 9 inhibitor","CDK1;CDK2;CDK9","Kinase inhibitor"]
["SH3BP5L","GSK2830371",0.498,0.0112,-0.143,0.597,-1.98,0.0482,0.0474,0.539,"+/0","Wip1 inhibitor","PPM1D","Other"]
["ZNF444","AZD7762",0.237,0.254,-0.465,0.0695,-2.13,0.0331,0.0326,0.539,"0/0","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["CMC2","Mitomycin_C",0.0218,0.917,-0.634,0.00832,-2.2,0.0277,0.0298,0.54,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["FARSB","Cisplatin",0.376,0.064,-0.343,0.194,-2.15,0.0314,0.0327,0.54,"0/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["KIF20B","Danusertib",0.522,0.0074,-0.213,0.428,-2.28,0.0229,0.0242,0.54,"+/0","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["LIMK2","Doxorubicin",-0.0331,0.875,0.642,0.0073,2.27,0.023,0.0243,0.54,"0/+","Topoisomerase II inhibitor","TOP2A;NOLC1","Conv.Chemo"]
["PLEKHF2","GDC_0084",-0.174,0.404,0.55,0.0274,2.27,0.0232,0.0249,0.54,"0/+","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["S100A6","Tasquinimod",-0.496,0.0117,0.272,0.307,2.35,0.0186,0.0206,0.54,"-/0","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["SPAST","Pevonedistat",0.0613,0.771,0.636,0.00805,1.97,0.0484,0.0475,0.54,"0/+","NAE inhibitor","NAE1","Metabolic modifier"]
["SLC38A10","Temsirolimus",-0.232,0.265,0.425,0.101,1.97,0.0486,0.0478,0.54,"0/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SLC25A30","Sunitinib",0.462,0.0199,-0.187,0.489,-1.97,0.0487,0.0479,0.54,"+/0","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["SMU1","Hydroxyurea",0.33,0.107,-0.332,0.208,-1.97,0.049,0.0482,0.54,"0/0","Antineoplastic agent","RRM1","Conv.Chemo"]
["TCIRG1","UCN_01",-0.367,0.0714,0.294,0.268,1.97,0.0492,0.0484,0.54,"0/0","PKCbeta, PDK1, Chk, Cdk2 inhibitor","PRKCB;PDPK1","Kinase inhibitor"]
["TRPM7","Silmitasertib",-0.244,0.24,0.458,0.0741,2.13,0.0334,0.0329,0.54,"0/0","CSNK2A1 inhibitor","CSNK2A1","Kinase inhibitor"]
["TSC22D4","Varlitinib",-0.251,0.226,0.452,0.0787,2.13,0.0334,0.0329,0.54,"0/0","EGFR HER2 inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["FZR1","IOX_1",-0.0805,0.702,0.585,0.0172,2.15,0.0317,0.033,0.541,"0/+","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["FADS1","Gandotinib",0.377,0.0632,-0.339,0.199,-2.14,0.0321,0.0333,0.541,"0/0","JAK2 inhibitor","JAK2;JAK1;FLT3;FLT4;FGFR2;TYK2;NTRK2;FGFR3;KDR;ALK","Kinase inhibitor"]
["PNPLA6","Duvelisib",-0.377,0.063,0.377,0.151,2.27,0.0234,0.0252,0.541,"0/0","PI3K inhibitor","PIK3CD","Kinase inhibitor"]
["MT-ND6","Daunorubicin",-0.13,0.535,0.579,0.0188,2.26,0.0236,0.0254,0.541,"0/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["PPP3CC","Spebrutinib",-0.104,0.622,0.615,0.0112,2.35,0.0189,0.0209,0.541,"0/+","BTK inhibitor","BTK","Kinase inhibitor"]
["STOM","PCI_34051",-0.146,0.485,0.493,0.0523,1.97,0.0494,0.0485,0.541,"0/0","HDAC8 inhibitor","HDAC8","Differentiating.epigenetic modifier"]
["SIRT1","AT9283",0.314,0.126,-0.347,0.188,-1.96,0.0495,0.0486,0.541,"0/0","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["SRP14","AZD1208",-0.263,0.204,0.395,0.13,1.96,0.0498,0.0489,0.541,"0/0","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["TSTA3","Rigosertib",-0.482,0.0148,0.215,0.424,2.12,0.0336,0.0332,0.541,"-/0","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["UGGT1","Duvelisib",-0.048,0.82,0.601,0.0138,2.12,0.0337,0.0332,0.541,"0/+","PI3K inhibitor","PIK3CD","Kinase inhibitor"]
["XRN2","Tamatinib",0.462,0.02,-0.237,0.377,-2.12,0.034,0.0335,0.541,"+/0","SYK inhibitor","SYK","Kinase inhibitor"]
["ZNF771","Exemestane",0.155,0.459,0.715,0.00185,2.12,0.0341,0.0336,0.541,"0/+","Aromatase inhibitor","CYP19A1","Hormone therapy"]
["CEP250","PD0325901",0.171,0.414,-0.534,0.0333,-2.19,0.0282,0.0303,0.542,"0/-","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["FBXW2","MK_2206",-0.302,0.143,0.412,0.113,2.14,0.0322,0.0335,0.542,"0/0","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["LYST","FRAX486",0.232,0.265,-0.506,0.0454,-2.27,0.0233,0.0246,0.542,"0/-","PAK1, 2, 3 inhibitor","PAK1","Kinase inhibitor"]
["IGFBP2","Pemetrexed",-0.199,0.34,0.531,0.0343,2.27,0.0233,0.0246,0.542,"0/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["NMNAT3","Abexinostat",-0.163,0.436,0.555,0.0255,2.26,0.0238,0.0256,0.542,"0/+","HDAC1 selective inhibitor","HDAC1","Differentiating.epigenetic modifier"]
["SEMA4D","Enzalutamide",0.575,2.64E-3,-0.163,0.546,-2.34,0.0191,0.0212,0.542,"+/0","AR antagonist","AR","Hormone therapy"]
["PPP2R5E","Gemcitabine",0.111,0.597,-0.609,0.0124,-2.34,0.0194,0.0214,0.542,"0/-","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["RPL6","AZD_6482",0.256,0.217,-0.504,0.0465,-2.33,0.0197,0.0217,0.542,"0/-","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["UBE2W","Idarubicin",-0.101,0.631,0.564,0.0228,2.12,0.0343,0.0338,0.542,"0/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["ZNF770","Vistusertib",0.24,0.247,-0.458,0.0744,-2.12,0.0344,0.0339,0.542,"0/0","mTOR inhibitor, ATP-competitive","MTOR","Kinase inhibitor"]
["WASHC2C","Navitoclax",0.418,0.0374,-0.285,0.285,-2.11,0.0347,0.0341,0.542,"+/0","Bcl-2,Bcl-XL inhibitor","BCL2;BCL2L2;BAD;BCL2L1;MCL1","Apoptotic modulator"]
["GBP5","Digoxin",0.0675,0.749,-0.591,0.0158,-2.14,0.0326,0.0339,0.543,"0/-","Cardiac glycoside","ATP1A1;ITGB1;ITGB3;ITGA3;ITGA1","Other"]
["FAM49B","Sitravatinib",-0.196,0.348,0.5,0.0488,2.14,0.0327,0.034,0.543,"0/+","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["INPP5D","AZD_8186",-0.258,0.213,0.484,0.0577,2.26,0.0237,0.025,0.543,"0/0","PI3K beta inhibitor","PIK3CG","Kinase inhibitor"]
["LIN7C","Gandotinib",0.136,0.518,-0.575,0.0199,-2.26,0.0238,0.0251,0.543,"0/-","JAK2 inhibitor","JAK2;JAK1;FLT3;FLT4;FGFR2;TYK2;NTRK2;FGFR3;KDR;ALK","Kinase inhibitor"]
["PMPCB","Carfilzomib",0.111,0.596,-0.59,0.0162,-2.26,0.0241,0.0259,0.543,"0/-","Proteasome inhibitor (20S subunit)","PSMB5;PSMB8;PSMB1;PSMB2;PSMB9;PSMB10","Protease.proteasome inhibitor"]
["NFATC4","Selumetinib",0.212,0.31,-0.517,0.0401,-2.25,0.0243,0.0261,0.543,"0/-","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["RAB6A","AT13148",-0.392,0.0527,0.38,0.147,2.33,0.02,0.0221,0.543,"0/0","p70S6K, PKA, ROCK (AKT) inhibitor","AKT1;AKT2;AKT3;RPS6KB1;ROCK1;ROCK2;PRKACA;PRKACB;PRKACG","Kinase inhibitor"]
["ZSWIM8","ABT_751",-0.594,1.73E-3,0.0539,0.843,2.11,0.0348,0.0342,0.543,"-/0","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["CFAP20","SGC_CBP30",0.165,0.43,-0.537,0.0321,-2.19,0.0285,0.0307,0.544,"0/-","CREBBP, EP300 bromodomain inhibitor","CREBBP","Differentiating.epigenetic modifier"]
["CYFIP2","Dasatinib",-0.289,0.162,0.437,0.0906,2.19,0.0286,0.0308,0.544,"0/0","ABL, Src, Kit, EphR Inhibitor","ABL1","Kinase inhibitor"]
["G6PD","Saracatinib",-0.311,0.131,0.401,0.124,2.13,0.033,0.0342,0.544,"0/0","Src, ABL inhibitor","ABL1;SRC;LCK;YES1;LYN;FYN;BLK;EGFR;KIT;EPHA2","Kinase inhibitor"]
["FOXO3B","Uprosertib",0.301,0.144,-0.409,0.116,-2.13,0.0332,0.0345,0.544,"0/0","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["ERCC3","Sonidegib",-0.133,0.525,0.544,0.0295,2.13,0.0336,0.0348,0.544,"0/+","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["METTL17","Tubastatin_A",-0.531,0.00637,0.197,0.465,2.26,0.0238,0.0252,0.544,"-/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["PIK3C2A","Gandotinib",0.398,0.049,-0.351,0.183,-2.25,0.0245,0.0263,0.544,"+/0","JAK2 inhibitor","JAK2;JAK1;FLT3;FLT4;FGFR2;TYK2;NTRK2;FGFR3;KDR;ALK","Kinase inhibitor"]
["NQO2","AT13148",-0.227,0.274,0.504,0.0464,2.25,0.0246,0.0263,0.544,"0/+","p70S6K, PKA, ROCK (AKT) inhibitor","AKT1;AKT2;AKT3;RPS6KB1;ROCK1;ROCK2;PRKACA;PRKACB;PRKACG","Kinase inhibitor"]
["PHKA2","Tubacin",-0.45,0.0238,0.291,0.273,2.25,0.0247,0.0265,0.544,"-/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["UTP20","Cerdulatinib",0.397,0.0497,-0.307,0.248,-2.11,0.0353,0.0346,0.544,"+/0","JAK, SYK inhibitor","JAK1;JAK2;JAK3;TYK2;SYK","Kinase inhibitor"]
["ZRANB2","GSK_1070916",0.335,0.102,-0.369,0.16,-2.1,0.0355,0.0349,0.544,"0/0","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["CCM2","Digoxin",0.135,0.52,-0.557,0.025,-2.18,0.0289,0.0311,0.545,"0/-","Cardiac glycoside","ATP1A1;ITGB1;ITGB3;ITGA3;ITGA1","Other"]
["FAM133B","Pictilisib",0.168,0.421,-0.517,0.0401,-2.12,0.0337,0.035,0.545,"0/-","PI3K inhibitor, pan-class I","PIK3CA;PIK3CB;PIK3CG;PIK3CD;MTOR","Kinase inhibitor"]
["FARP2","Alisertib",0.366,0.0719,-0.344,0.193,-2.12,0.0339,0.0351,0.545,"0/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["GNG5","Cabozantinib",0.0913,0.664,-0.572,0.0207,-2.12,0.034,0.0353,0.545,"0/-","VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor","KDR;MET;FLT3;KIT;RET;TEK","Kinase inhibitor"]
["NPEPL1","Tubastatin_A",-0.284,0.169,0.456,0.0757,2.24,0.025,0.0267,0.545,"0/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["PTGR2","BMS_911543",0.0821,0.696,-0.623,0.00991,-2.32,0.0202,0.0222,0.545,"0/-","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["UBR3","Topotecan",0.589,0.00196,-0.0593,0.827,-2.1,0.0356,0.035,0.545,"+/0","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["ZNF292","Asciminib",0.347,0.0889,-0.356,0.176,-2.1,0.0358,0.0352,0.545,"0/0","Allosteric ABL inhibitor, blocks myristoyl binding","ABL1","Kinase inhibitor"]
["TRIM47","Tozasertib",-0.209,0.316,0.479,0.0605,2.1,0.0359,0.0353,0.545,"0/0","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["TUBA4B","CEP_37440",-0.254,0.221,0.441,0.0871,2.1,0.0361,0.0356,0.545,"0/0","ALK inhibitor","ALK;AXL;MET;TYRO3;MERTK;KDR;DDR1","Kinase inhibitor"]
["TRMT112","E7820",0.446,0.0253,-0.247,0.357,-2.09,0.0364,0.0357,0.545,"+/0","Integrin alpha2 expression inhibitor","ITGA2","Other"]
["USP7","Mercaptopurine",0.194,0.352,-0.489,0.0547,-2.09,0.0366,0.0359,0.545,"0/0","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["CEBPG","Triapine",0.446,0.0256,-0.277,0.299,-2.18,0.029,0.0312,0.546,"+/0","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["DOCK10","Givinostat",0.527,0.00682,-0.175,0.517,-2.18,0.0293,0.0315,0.546,"+/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC10","Differentiating.epigenetic modifier"]
["FEZ2","Omacetaxine",-0.35,0.0859,0.358,0.173,2.12,0.0343,0.0355,0.546,"0/0","Protein synthesis inhib (80 S ribosome)","RPL3","Conv.Chemo"]
["EIF2AK4","Finasteride",-0.15,0.475,-0.712,1.99E-3,-2.11,0.0345,0.0357,0.546,"0/-","type II 5-alpha reductase inhibitor","SRD5A2","Hormone therapy"]
["MPV17","AZD_5438",-0.151,0.472,0.562,0.0235,2.25,0.0244,0.0257,0.546,"0/+","CDK1, 2, 9 inhibitor","CDK1;CDK2;CDK9","Kinase inhibitor"]
["ITIH2","Simvastatin",-0.12,0.568,0.582,0.018,2.25,0.0246,0.0259,0.546,"0/+","HMG CoA reductase inhibitor","HMGCR","Metabolic modifier"]
["RAB8B","Crenolanib",-0.32,0.119,0.446,0.0833,2.32,0.0204,0.0224,0.546,"0/0","PDGFRA and PDGFRB inhibitor","PDGFRA","Kinase inhibitor"]
["ZNF26","Palomid_529",-0.163,0.435,-0.714,1.9E-3,-2.09,0.0369,0.0362,0.546,"0/-","AKT, MTOR, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3;MTOR","Kinase inhibitor"]
["WSB1","Romidepsin",-0.197,0.345,0.485,0.0569,2.08,0.0371,0.0364,0.546,"0/0","HDAC inhibitor","HDAC1;HDAC2","Differentiating.epigenetic modifier"]
["DNAJB2","Rigosertib",-0.419,0.0373,0.305,0.25,2.18,0.0295,0.0317,0.547,"-/0","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["FAM83D","Selinexor",0.529,0.0065,-0.148,0.584,-2.11,0.0347,0.0359,0.547,"+/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["FRRS1","Cisplatin",0.454,0.0228,-0.244,0.363,-2.11,0.0349,0.0361,0.547,"+/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["IPP","Ribociclib",0.605,0.00135,-0.0845,0.756,-2.25,0.0247,0.0259,0.547,"+/0","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["PACSIN1","Glasdegib",-0.0401,0.849,-0.676,0.00402,-2.24,0.0254,0.0272,0.547,"0/-","Smo inhibitor","SMO","Hedgehog inhibitor"]
["RTN3","Galiellalactone",0.206,0.323,-0.538,0.0317,-2.31,0.0206,0.0227,0.547,"0/-","STAT3-DNA interaction inhibitor","STAT3","Other"]
["PPM1K","Toremifene",-0.295,0.152,0.466,0.0688,2.31,0.0207,0.0227,0.547,"0/0","Selective estrogen receptor modulator","ESR1;SHBG","Hormone therapy"]
["TXNL4A","Tubastatin_A",-0.341,0.0952,0.356,0.176,2.08,0.0375,0.0367,0.547,"0/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["DBT","GSK269962",-0.585,0.00213,0.0897,0.741,2.17,0.0299,0.032,0.548,"-/0","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["COX15","AZD_8186",-0.295,0.152,0.427,0.0994,2.17,0.0299,0.0321,0.548,"0/0","PI3K beta inhibitor","PIK3CG","Kinase inhibitor"]
["GRK3","Sabutoclax",-0.281,0.174,0.42,0.105,2.1,0.0354,0.0366,0.548,"0/0","pan Bcl-2 family inhibitor","BCL2;BCL2L1;MCL1;BCL2A1","Apoptotic modulator"]
["MAP3K3","UCN_01",-0.698,1.05E-4,-0.0799,0.769,2.24,0.0251,0.0264,0.548,"-/0","PKCbeta, PDK1, Chk, Cdk2 inhibitor","PRKCB;PDPK1","Kinase inhibitor"]
["MYH9","BMS_754807",-0.402,0.0464,0.34,0.197,2.23,0.0257,0.0275,0.548,"-/0","IGF1R inhibitor","IGF1R","Kinase inhibitor"]
["NSUN6","Toremifene",-0.0347,0.869,0.632,0.00861,2.23,0.0258,0.0276,0.548,"0/+","Selective estrogen receptor modulator","ESR1;SHBG","Hormone therapy"]
["RHOH","Amsacrine",-0.066,0.754,0.63,0.00891,2.31,0.021,0.023,0.548,"0/+","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["TTL","Palbociclib",0.241,0.247,-0.448,0.0819,-2.08,0.0376,0.0368,0.548,"0/0","Topoisomerase I inhibitor, Camptothecin analog","CDK4;CDK6","Kinase inhibitor"]
["CDCA5","Verdinexor",0.296,0.151,-0.425,0.1,-2.17,0.0299,0.0321,0.549,"0/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["CIB1","Belinostat",-0.285,0.167,0.434,0.0927,2.17,0.0301,0.0323,0.549,"0/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["FBLL1","Sepantronium_bromide",0.397,0.0494,-0.304,0.252,-2.1,0.0358,0.037,0.549,"+/0","Survivin inhibitor","BIRC5","Apoptotic modulator"]
["HDHD5","GSK_2334470",0.215,0.302,-0.474,0.0636,-2.1,0.036,0.0371,0.549,"0/0","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["MICOS13","A_1331852",0.0988,0.639,0.707,0.00219,2.24,0.0254,0.0266,0.549,"0/+","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2;MCL1","Apoptotic modulator"]
["MYO1E","Epirubicin",-0.188,0.368,0.529,0.0352,2.23,0.026,0.0278,0.549,"0/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["PSEN1","AT9283",-0.495,0.0118,0.257,0.336,2.31,0.0211,0.0232,0.549,"-/0","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["XRCC4","AT13148",0.112,0.595,-0.547,0.0283,-2.08,0.0379,0.0371,0.549,"0/-","p70S6K, PKA, ROCK (AKT) inhibitor","AKT1;AKT2;AKT3;RPS6KB1;ROCK1;ROCK2;PRKACA;PRKACB;PRKACG","Kinase inhibitor"]
["USP33","Eltanexor",0.0906,0.667,-0.561,0.0238,-2.07,0.0382,0.0374,0.549,"0/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["EEF1D","Doramapimod",0.455,0.0222,-0.261,0.329,-2.17,0.0302,0.0324,0.55,"+/0","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["DDX55","Masitinib",0.168,0.421,-0.528,0.0356,-2.16,0.0305,0.0326,0.55,"0/-","KIT inhibitor","KIT","Kinase inhibitor"]
["HMBOX1","A_1331852",-0.392,0.0524,0.308,0.246,2.09,0.0363,0.0374,0.55,"0/0","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2;MCL1","Apoptotic modulator"]
["EXOC5","OSU_03012",-0.546,0.00473,0.118,0.663,2.09,0.0364,0.0376,0.55,"-/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["EMG1","Idelalisib",0.158,0.451,-0.517,0.0405,-2.09,0.0367,0.0378,0.55,"0/-","PI3K inhibitor, p110-selective","PIK3CD","Kinase inhibitor"]
["NSL1","Vactosertib_TEW_7197",0.348,0.0885,-0.392,0.133,-2.22,0.0263,0.0282,0.55,"0/0","TGF receptor ALK4, ALK5 inhibitor","TGFBR1;ACVR1B","Kinase inhibitor"]
["NIBAN1","Alisertib",-0.432,0.0312,0.304,0.253,2.22,0.0266,0.0284,0.55,"-/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["RETREG3","8_amino_adenosine",-0.366,0.072,0.398,0.127,2.3,0.0213,0.0234,0.55,"0/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["ZHX1","Dovitinib",0.0811,0.7,-0.567,0.022,-2.07,0.0384,0.0375,0.55,"0/-","FGFR inhibitor","FGFR1;FGFR3;KIT;FLT3;FLT4","Kinase inhibitor"]
["UBFD1","AZD_5363",0.162,0.439,-0.508,0.0446,-2.07,0.0386,0.0378,0.55,"0/-","AKT inhibitor","AKT1;AKT2;AKT3;ROCK2","Kinase inhibitor"]
["DCTPP1","Floxuridine",0.228,0.272,-0.481,0.0595,-2.16,0.0306,0.0329,0.551,"0/0","Antimetabolite, Analog of 5-fluorouracil","TYMS","Conv.Chemo"]
["CUL9","8_amino_adenosine",-0.583,0.00222,0.0877,0.747,2.16,0.0309,0.0331,0.551,"-/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["GRAMD1B","Methotrexate",0.119,0.572,0.691,0.00304,2.09,0.0368,0.0379,0.551,"0/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["HERPUD1","Tipifarnib",0.161,0.443,-0.514,0.0418,-2.09,0.037,0.0381,0.551,"0/-","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["HPDL","ML390",-0.256,0.216,0.436,0.0917,2.08,0.0371,0.0383,0.551,"0/0","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["LIMD2","Temsirolimus",0.517,0.00812,-0.205,0.446,-2.23,0.0257,0.0269,0.551,"+/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["MED8","Duvelisib",-0.0036,0.986,-0.654,5.96E-3,-2.23,0.0259,0.0272,0.551,"0/-","PI3K inhibitor","PIK3CD","Kinase inhibitor"]
["NET1","GSK_461364",0.373,0.066,-0.365,0.165,-2.21,0.0268,0.0286,0.551,"0/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["NUDC","AZD6738",0.273,0.186,-0.457,0.0752,-2.21,0.027,0.0287,0.551,"0/0","ATR inihibitor","ATR","Kinase inhibitor"]
["MYO5A","Tosedostat",-0.18,0.389,0.53,0.0346,2.21,0.0272,0.0289,0.551,"0/+","Aminopeptidase inhibitor","ANPEP","Protease.proteasome inhibitor"]
["RETREG2","Tivozanib",-0.221,0.288,0.521,0.0383,2.3,0.0217,0.0238,0.551,"0/+","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["RNF146","Sunitinib",0.445,0.026,-0.314,0.237,-2.29,0.0218,0.0238,0.551,"+/0","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["RPL37","Triciribine",0.267,0.197,-0.483,0.058,-2.29,0.0221,0.0242,0.551,"0/0","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["SEC11A","GSK923295",-0.362,0.0752,0.397,0.128,2.29,0.0223,0.0244,0.551,"0/0","CENP-E inhibitor","CENPE","Kinesin inhibitor"]
["VIRMA","Tazemetostat",0.56,0.00359,-0.0894,0.742,-2.07,0.0389,0.038,0.551,"+/0","EZH2 inhibitor","EZH2","Differentiating.epigenetic modifier"]
["CDKN3","Palbociclib",0.575,2.63E-3,-0.098,0.718,-2.15,0.0312,0.0334,0.552,"+/0","Topoisomerase I inhibitor, Camptothecin analog","CDK4;CDK6","Kinase inhibitor"]
["FLVCR1","PF_670462",0.225,0.28,-0.461,0.0723,-2.08,0.0376,0.0387,0.552,"0/0","CK1epsilon and CK1delta inhibitor","CSNK1D;CSNK1E","Kinase inhibitor"]
["EIF3I","Deferoxamine",0.261,0.207,-0.429,0.0969,-2.08,0.0378,0.039,0.552,"0/0","Iron chelator","APP","Other"]
["MFAP1","MST_312",0.54,0.00537,-0.172,0.523,-2.22,0.0262,0.0275,0.552,"+/0","Telomerase inhibitor","TERT","Other"]
["KPTN","GSK269962",-0.348,0.0878,-0.815,1.22E-4,-2.22,0.0264,0.0277,0.552,"0/-","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["IST1","Topotecan",-0.38,0.061,0.359,0.172,2.22,0.0266,0.0279,0.552,"0/0","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["RUSC1","Fludarabine",-0.418,0.0375,0.34,0.198,2.28,0.0224,0.0244,0.552,"-/0","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["TXNRD1","Hydroxyurea",-0.358,0.0793,0.335,0.205,2.06,0.039,0.0383,0.552,"0/0","Antineoplastic agent","RRM1","Conv.Chemo"]
["UTP15","Topotecan",0.529,0.0065,-0.131,0.628,-2.06,0.0392,0.0384,0.552,"+/0","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["CTU2","AZD7762",0.354,0.0829,-0.366,0.164,-2.15,0.0314,0.0336,0.553,"0/0","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["CLASRP","8_amino_adenosine",-0.0631,0.765,-0.673,4.3E-3,-2.15,0.0315,0.0337,0.553,"0/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["FAM111B","Fostamatinib",-0.0216,0.918,-0.634,0.00839,-2.08,0.038,0.0391,0.553,"0/-","SYK inhibitor","SYK","Kinase inhibitor"]
["EIF3G","Mercaptopurine",0.421,0.0359,-0.27,0.313,-2.07,0.038,0.0392,0.553,"+/0","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["EPC2","E7820",0.322,0.117,-0.372,0.156,-2.07,0.0384,0.0395,0.553,"0/0","Integrin alpha2 expression inhibitor","ITGA2","Other"]
["GNA13","FRAX486",-0.084,0.69,0.565,0.0227,2.07,0.0386,0.0396,0.553,"0/+","PAK1, 2, 3 inhibitor","PAK1","Kinase inhibitor"]
["HBP1","Azacitidine",-0.366,0.0722,0.327,0.216,2.07,0.0387,0.0398,0.553,"0/0","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["LRBA","Gilteritinib",-0.396,0.0503,0.342,0.195,2.21,0.0268,0.028,0.553,"0/0","FLT3, AXL inhibitor","FLT3","Kinase inhibitor"]
["MIEF1","Pemetrexed",0.455,0.0222,-0.275,0.303,-2.21,0.0271,0.0283,0.553,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["KHNYN","PF_00477736",-0.0559,0.791,0.615,0.0112,2.21,0.0271,0.0284,0.553,"0/+","CHEK1 inhibitor","CHEK1;KDR;FLT3;YES1;CHEK2","Kinase inhibitor"]
["NUFIP2","Rigosertib",0.456,0.022,-0.272,0.308,-2.2,0.0275,0.0292,0.553,"+/0","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["PTAR1","S_63845",0.26,0.21,-0.486,0.056,-2.28,0.0227,0.0247,0.553,"0/0","MCL-1 inhibitor","MCL1","Apoptotic modulator"]
["PPCDC","Aldoxorubicin",-0.259,0.211,0.487,0.0559,2.28,0.0227,0.0248,0.553,"0/0","Topoisomerase II inhibitor, Albumin binding","TOP2A;TOP2B","Conv.Chemo"]
["TRIM68","Megestrol_acetate",-0.464,0.0194,0.214,0.427,2.06,0.0397,0.0389,0.553,"-/0","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["CCDC88C","Tamatinib",-0.528,0.00663,0.162,0.549,2.15,0.0317,0.0339,0.554,"-/0","SYK inhibitor","SYK","Kinase inhibitor"]
["CEMIP2","MST_312",-0.165,0.43,0.526,0.0365,2.15,0.0318,0.034,0.554,"0/+","Telomerase inhibitor","TERT","Other"]
["HDAC6","Tosedostat",0.153,0.466,-0.514,0.0416,-2.07,0.0389,0.04,0.554,"0/-","Aminopeptidase inhibitor","ANPEP","Protease.proteasome inhibitor"]
["EIF1B","Tacedinaline",0.414,0.0397,-0.274,0.305,-2.06,0.0392,0.0403,0.554,"+/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["L3MBTL3","Methylprednisolone",0.141,0.501,-0.558,0.0248,-2.21,0.0274,0.0286,0.554,"0/-","Glucocorticoid, immunomodulatory agent","NR3C1","Immunomodulatory"]
["LPIN2","Merestinib",-0.217,0.297,0.5,0.0484,2.2,0.0277,0.0289,0.554,"0/+","MET inhibitor","MET","Kinase inhibitor"]
["HVCN1","Pevonedistat",-0.0803,0.703,0.598,0.0145,2.2,0.0278,0.029,0.554,"0/+","NAE inhibitor","NAE1","Metabolic modifier"]
["NKTR","Tacrolimus",0.156,0.455,-0.545,0.0289,-2.2,0.0279,0.0297,0.554,"0/-","binds FKBP12, causes inhibition of calcineurin","FKBP1A","Rapalog"]
["PDE8A","Sepantronium_bromide",-0.106,0.614,0.579,0.0187,2.2,0.0281,0.0299,0.554,"0/+","Survivin inhibitor","BIRC5","Apoptotic modulator"]
["RPS6KA3","Axitinib",-0.385,0.0572,0.37,0.158,2.27,0.023,0.0251,0.554,"0/0","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["USP30","Digoxin",-0.506,0.00986,0.16,0.555,2.05,0.04,0.0392,0.554,"-/0","Cardiac glycoside","ATP1A1;ITGB1;ITGB3;ITGA3;ITGA1","Other"]
["UXS1","PD0325901",0.491,0.0126,-0.177,0.512,-2.05,0.0404,0.0395,0.554,"+/0","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["CEP295","AT9283",0.358,0.0791,-0.358,0.173,-2.14,0.0322,0.0344,0.555,"0/0","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["FTSJ3","Crenolanib",0.0599,0.776,-0.579,0.0188,-2.06,0.0393,0.0404,0.555,"0/-","PDGFRA and PDGFRB inhibitor","PDGFRA","Kinase inhibitor"]
["GM2A","Erlotinib",-0.0977,0.642,0.553,0.0264,2.06,0.0395,0.0405,0.555,"0/+","EGFR inhibitor","EGFR","Kinase inhibitor"]
["HYLS1","Perifosine",0.051,0.809,0.675,0.0041,2.2,0.0279,0.0291,0.555,"0/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["METTL5","Thioguanine",0.47,0.0177,-0.252,0.346,-2.2,0.0281,0.0294,0.555,"+/0","Antimetabolite, Purine analog","DNMT1","Conv.Chemo"]
["MRGBP","Cabazitaxel",0.0132,0.95,-0.638,0.00789,-2.19,0.0283,0.0295,0.555,"0/-","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["NUF2","GSK923295",0.354,0.083,-0.377,0.15,-2.19,0.0285,0.0303,0.555,"0/0","CENP-E inhibitor","CENPE","Kinesin inhibitor"]
["RNASEH2A","GSK2830371",0.595,0.0017,-0.108,0.69,-2.27,0.0232,0.0253,0.555,"+/0","Wip1 inhibitor","PPM1D","Other"]
["PPFIA3","Azacitidine",0.0469,0.824,-0.633,0.0085,-2.27,0.0234,0.0255,0.555,"0/-","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["PRXL2B","LY_2874455",-0.349,0.0872,0.403,0.122,2.26,0.0236,0.0257,0.555,"0/0","FGFR inhibitor","FGFR1;FGFR2;FGFR3","Kinase inhibitor"]
["RPL32","Bexarotene",0.0529,0.802,0.688,0.00322,2.26,0.0237,0.0259,0.555,"0/+","Antineoplastic agent, retinoid specifically selective for retinoid X receptors","RXRA;RXRB","Differentiating.epigenetic modifier"]
["ZPR1","AZD7762",0.271,0.189,-0.412,0.113,-2.05,0.0406,0.0396,0.555,"0/0","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["DNASE2","Lonafarnib",0.198,0.343,-0.499,0.0493,-2.14,0.0325,0.0347,0.556,"0/-","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["DHRS7B","Finasteride",0.0332,0.875,-0.614,0.0115,-2.14,0.0325,0.0347,0.556,"0/-","type II 5-alpha reductase inhibitor","SRD5A2","Hormone therapy"]
["ETFA","Panobinostat",-0.218,0.296,0.461,0.0724,2.06,0.0397,0.0408,0.556,"0/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["HADHA","Cytarabine",-0.511,0.00897,0.152,0.573,2.05,0.0401,0.0411,0.556,"-/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["MIS12","Tamatinib",-0.459,0.021,0.265,0.322,2.19,0.0283,0.0295,0.556,"-/0","SYK inhibitor","SYK","Kinase inhibitor"]
["INPP5D","8_amino_adenosine",-0.325,0.112,0.405,0.12,2.19,0.0283,0.0296,0.556,"0/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["PEX12","NMS_873",-0.44,0.0277,0.285,0.285,2.19,0.0287,0.0306,0.556,"-/0","p97, VCP inhibitor","VCP","Other"]
["NLRX1","Vistusertib",-0.534,0.00595,0.166,0.539,2.18,0.029,0.0308,0.556,"-/0","mTOR inhibitor, ATP-competitive","MTOR","Kinase inhibitor"]
["SART3","Midostaurin",-0.301,0.144,0.446,0.0832,2.26,0.0239,0.026,0.556,"0/0","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["RINT1","Palomid_529",-0.149,0.476,0.564,0.0229,2.25,0.0241,0.0262,0.556,"0/+","AKT, MTOR, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3;MTOR","Kinase inhibitor"]
["UBAP2L","Cerdulatinib",0.508,0.00949,-0.153,0.571,-2.04,0.0411,0.0402,0.556,"+/0","JAK, SYK inhibitor","JAK1;JAK2;JAK3;TYK2;SYK","Kinase inhibitor"]
["DOK2","Ivosidenib",-0.0995,0.636,0.57,0.0213,2.13,0.0328,0.035,0.557,"0/+","IDH1 R132H and R132C inhibitor","IDH1","Differentiating.epigenetic modifier"]
["EMG1","BMS863233",0.25,0.228,-0.431,0.0953,-2.05,0.0404,0.0415,0.557,"0/0","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["HLA-DRB1","Saracatinib",-0.292,0.156,0.393,0.132,2.05,0.0406,0.0416,0.557,"0/0","Src, ABL inhibitor","ABL1;SRC;LCK;YES1;LYN;FYN;BLK;EGFR;KIT;EPHA2","Kinase inhibitor"]
["GATAD1","Ridaforolimus",-0.43,0.0318,0.25,0.351,2.04,0.0409,0.0419,0.557,"-/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["LPCAT3","OSU_03012",-0.343,0.0931,0.386,0.139,2.19,0.0287,0.03,0.557,"0/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["NELFCD","AMG319",-0.428,0.0326,0.296,0.266,2.18,0.0293,0.031,0.557,"-/0","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["ORAI1","Sapanisertib",-0.529,0.0065,0.171,0.526,2.18,0.0293,0.0311,0.557,"-/0","mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["VIM","BMS_754807",-0.343,0.0936,0.343,0.194,2.04,0.0412,0.0402,0.557,"0/0","IGF1R inhibitor","IGF1R","Kinase inhibitor"]
["TXNRD2","NVP_BGT226",-0.489,0.0131,0.177,0.511,2.04,0.0412,0.0403,0.557,"-/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CG;MTOR","Kinase inhibitor"]
["TRIM4","AT9283",-0.0958,0.649,0.549,0.0276,2.04,0.0415,0.0406,0.557,"0/+","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["DPP9","Gedatolisib",-0.452,0.0232,0.252,0.347,2.13,0.0332,0.0354,0.558,"-/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CG;MTOR","Kinase inhibitor"]
["GALE","CC_223",-0.245,0.238,0.434,0.0932,2.04,0.0411,0.0421,0.558,"0/0","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["GATD1","Carboplatin",0.375,0.0646,-0.309,0.244,-2.04,0.0412,0.0422,0.558,"0/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["NFYA","Entinostat",0.192,0.358,-0.513,0.0421,-2.18,0.0295,0.0313,0.558,"0/-","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["OXSM","Bortezomib",0.0889,0.673,-0.586,0.0171,-2.17,0.0297,0.0315,0.558,"0/-","Proteasome inhibitor (26S subunit)","PSMB5;PSMB1","Protease.proteasome inhibitor"]
["ZNF655","Dasatinib",-0.196,0.348,0.473,0.0642,2.04,0.0417,0.0407,0.558,"0/0","ABL, Src, Kit, EphR Inhibitor","ABL1","Kinase inhibitor"]
["TRNT1","Vidofludimus",-0.111,0.597,0.537,0.0319,2.04,0.0418,0.0408,0.558,"0/+","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["TOMM6","Cytarabine.Idarubicin",0.458,0.0212,-0.213,0.428,-2.03,0.0419,0.0409,0.558,"+/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["CENPK","Amsacrine",0.291,0.158,-0.416,0.109,-2.13,0.0336,0.0357,0.559,"0/0","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["G3BP1","AT13148",0.246,0.236,-0.432,0.0948,-2.04,0.0414,0.0424,0.559,"0/0","p70S6K, PKA, ROCK (AKT) inhibitor","AKT1;AKT2;AKT3;RPS6KB1;ROCK1;ROCK2;PRKACA;PRKACB;PRKACG","Kinase inhibitor"]
["EIF4EBP3","Venetoclax",-0.093,0.658,0.551,0.027,2.04,0.0416,0.0426,0.559,"0/+","Bcl-2 selective inhibitor","BCL2","Apoptotic modulator"]
["HLTF","Glesatinib",0.093,0.658,-0.55,0.0272,-2.04,0.0417,0.0427,0.559,"0/-","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["MPP1","MK_2206",0.191,0.36,-0.514,0.0415,-2.18,0.0293,0.0306,0.559,"0/-","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["KIF18A","Omaveloxolone",0.541,0.00522,-0.155,0.567,-2.18,0.0294,0.0307,0.559,"+/0","Nrf2 activator","NFE2L2","Other"]
["NOL3","Acalabrutinib",-0.439,0.028,0.28,0.293,2.17,0.03,0.0317,0.559,"-/0","BTK inhibitor","BTK","Kinase inhibitor"]
["PEX10","Cytarabine",0.139,0.507,-0.55,0.0273,-2.17,0.0302,0.0319,0.559,"0/-","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["TTC1","AZD_1080",0.333,0.104,-0.35,0.184,-2.03,0.042,0.041,0.559,"0/0","GSK3 inhibitor","GSK3B;GSK3A","Kinase inhibitor"]
["ZC3H15","Danusertib",0.412,0.0407,-0.266,0.319,-2.03,0.0421,0.0411,0.559,"+/0","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["WDR43","Perifosine",-0.0641,0.761,0.569,0.0215,2.03,0.0424,0.0413,0.559,"0/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["CRAMP1","8_chloro_adenosine",-0.567,3.13E-3,0.0989,0.716,2.12,0.0339,0.0361,0.56,"-/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["CRTAP","AZD8055",-0.125,0.552,0.548,0.0279,2.12,0.0341,0.0362,0.56,"0/+","mTOR inhibitor","MTOR","Kinase inhibitor"]
["EXD2","Acitretin",-0.125,0.551,0.526,0.0363,2.03,0.0422,0.0432,0.56,"0/+","Retinoic acid receptor agonist","RARA;RARB;RXRA;RXRB;RXRG","Differentiating.epigenetic modifier"]
["MLLT10","Cytarabine.Idarubicin",-0.0166,0.937,-0.651,0.00629,-2.17,0.0297,0.0309,0.56,"0/-","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["MESD","Azacitidine",-0.368,0.0706,0.357,0.174,2.17,0.0299,0.0311,0.56,"0/0","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["PIK3R1","Agerafenib_CEP_32496",-0.248,0.231,0.465,0.0695,2.16,0.0304,0.0322,0.56,"0/0","BRAF(V600E) inhibitor","BRAF;RAF1;KIT;RET;LCK;ABL1;PDGFRB;CSF1R;MET;EGFR;KDR;EPHA2","Kinase inhibitor"]
["PCBP3","Temsirolimus",0.156,0.456,-0.536,0.0322,-2.16,0.0306,0.0323,0.56,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["RPS6KA1","Erastin",-0.343,0.0932,0.402,0.122,2.24,0.025,0.0272,0.56,"0/0","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["RHOT1","Carfilzomib",0.275,0.184,-0.463,0.0708,-2.24,0.0251,0.0273,0.56,"0/0","Proteasome inhibitor (20S subunit)","PSMB5;PSMB8;PSMB1;PSMB2;PSMB9;PSMB10","Protease.proteasome inhibitor"]
["SEC11C","Axitinib",0.153,0.465,-0.557,0.0251,-2.24,0.0253,0.0275,0.56,"0/-","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["RNF10","Fimepinostat_CUDC_907",-0.406,0.044,0.337,0.202,2.23,0.0255,0.0277,0.56,"-/0","HDAC1, 2, 3, 10  and 11, PI3Kalpha inhibitor","HDAC1;HDAC2;HDAC3;HDAC10;HDAC11;PIK3CA","Differentiating.epigenetic modifier"]
["ZNF773","Nelarabine",-0.185,0.375,0.479,0.0603,2.03,0.0425,0.0415,0.56,"0/0","Antimetabolite, Nucleoside analog, DNA, RNA synth inhibitor","DNA","Conv.Chemo"]
["VPS45","VS_4718",0.196,0.349,-0.471,0.0657,-2.03,0.0427,0.0417,0.56,"0/0","FAK inhibitor","PTK2","Kinase inhibitor"]
["DUSP22","Pracinostat",0.394,0.0512,-0.313,0.238,-2.12,0.0343,0.0365,0.561,"0/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["DCD","Belinostat",-0.238,0.253,0.46,0.0732,2.11,0.0346,0.0368,0.561,"0/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["GTF2H2","Gandotinib",0.24,0.248,-0.434,0.0928,-2.03,0.0425,0.0435,0.561,"0/0","JAK2 inhibitor","JAK2;JAK1;FLT3;FLT4;FGFR2;TYK2;NTRK2;FGFR3;KDR;ALK","Kinase inhibitor"]
["GRN","NVP_BHG712",-0.502,0.0105,0.155,0.566,2.03,0.0427,0.0437,0.561,"-/0","EphB4 inhibitor","EPHB4","Kinase inhibitor"]
["ITPKB","Rocilinostat",0.488,0.0134,-0.222,0.409,-2.17,0.0301,0.0313,0.561,"+/0","HDAC6 selective inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["NTHL1","Givinostat",-0.51,0.00918,0.19,0.482,2.16,0.0309,0.0327,0.561,"-/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC10","Differentiating.epigenetic modifier"]
["POLE2","PAC_1",0.273,0.186,-0.441,0.0874,-2.15,0.0312,0.0329,0.561,"0/0","procaspase-3 activator","CASP3","Apoptotic modulator"]
["PGM3","Selumetinib",-0.252,0.225,0.459,0.0738,2.15,0.0313,0.0331,0.561,"0/0","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["RAB11A","Deferoxamine",-0.0664,0.752,-0.689,0.00317,-2.23,0.0259,0.0281,0.561,"0/-","Iron chelator","APP","Other"]
["RNF181","Mercaptopurine",0.349,0.0873,-0.392,0.133,-2.22,0.0261,0.0283,0.561,"0/0","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["ZNF414","Crenolanib",0.0109,0.959,0.617,0.0109,2.03,0.0427,0.0417,0.561,"0/+","PDGFRA and PDGFRB inhibitor","PDGFRA","Kinase inhibitor"]
["ZDHHC3","Ridaforolimus",-0.216,0.299,0.453,0.0782,2.02,0.043,0.042,0.561,"0/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["WDR1","Dactinomycin",-0.292,0.156,0.385,0.141,2.02,0.0431,0.0421,0.561,"0/0","RNA and DNA synthesis inhibitor","DNA","Conv.Chemo"]
["CIR1","Brigatinib",-0.244,0.239,0.453,0.0779,2.11,0.0348,0.037,0.562,"0/0","ALK inhibitor, including gatekeeper mutant ALK","ALK;ROS1;IGF1R;EGFR;INSR;ABL1;FLT3;MET;ERBB2;ERBB4","Kinase inhibitor"]
["EIF2AK3","Perifosine",-0.0753,0.721,0.56,0.0242,2.02,0.0431,0.0441,0.562,"0/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["GINS3","GSK650394",0.263,0.203,-0.411,0.114,-2.02,0.0433,0.0443,0.562,"0/0","SGK1 and 2 inhibitor","SGK1","Kinase inhibitor"]
["KRT78","Itraconazole",-0.507,0.00963,0.197,0.466,2.17,0.0302,0.0314,0.562,"-/0","antifungal, hedgehog signaling inhibitor","CYP51A1;CYP3A4","Other"]
["PLPP1","Glasdegib",-0.493,0.0122,0.209,0.438,2.15,0.0315,0.0333,0.562,"-/0","Smo inhibitor","SMO","Hedgehog inhibitor"]
["MSI2","EPZ015666",0.337,0.0997,-0.381,0.145,-2.15,0.0315,0.0333,0.562,"0/0","PRMT5 inhibitor","PRMT5","Differentiating.epigenetic modifier"]
["NEO1","Midostaurin",-0.546,0.00475,0.137,0.613,2.15,0.0319,0.0336,0.562,"-/0","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["PAPOLG","Tacedinaline",0.0935,0.657,-0.576,0.0196,-2.14,0.032,0.0338,0.562,"0/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["PEX7","BX_912",0.0358,0.865,-0.612,0.0117,-2.14,0.0324,0.0341,0.562,"0/-","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["SART1","Vincristine",0.252,0.224,-0.477,0.0616,-2.22,0.0263,0.0285,0.562,"0/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB;TUBA4A","Conv.Chemo"]
["RAMAC","IOX_2",-0.0604,0.774,0.614,0.0114,2.22,0.0266,0.0288,0.562,"0/+","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["QTRT1","CUDC_305",0.313,0.127,-0.423,0.103,-2.22,0.0267,0.0289,0.562,"0/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["RPL7A","A_1210477",-0.311,0.131,0.424,0.101,2.21,0.0268,0.029,0.562,"0/0","MCL-1 inhibitor","MCL1","Apoptotic modulator"]
["ZZEF1","LY_2874455",0.0183,0.931,-0.597,0.0147,-2.02,0.0434,0.0424,0.562,"0/-","FGFR inhibitor","FGFR1;FGFR2;FGFR3","Kinase inhibitor"]
["DUSP19","AT_406",0.455,0.0224,-0.242,0.366,-2.11,0.0349,0.0371,0.563,"+/0","XIAP, cIAP1, cIAP2 inhibitor","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["ERH","Panobinostat",-0.131,0.533,0.518,0.0397,2.02,0.0436,0.0446,0.563,"0/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["HNRNPA2B1","SAR405838",0.371,0.0679,-0.306,0.249,-2.02,0.0436,0.0446,0.563,"0/0","MDM2 inhibitor","MDM2;TP53","Apoptotic modulator"]
["EIF2B3","Sunitinib",0.352,0.0846,-0.325,0.219,-2.01,0.044,0.0449,0.563,"0/0","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["ING5","ML390",0.317,0.122,-0.404,0.12,-2.16,0.0304,0.0316,0.563,"0/0","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["MAP2K1","ARV_825",-0.185,0.376,0.515,0.0411,2.16,0.0305,0.0317,0.563,"0/+","BET-targeting PROTAC","BRD4","Differentiating.epigenetic modifier"]
["MYL12B","Lonafarnib",-0.315,0.126,0.399,0.126,2.14,0.0325,0.0342,0.563,"0/0","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["PHKG2","VS_4718",0.106,0.613,-0.565,0.0226,-2.14,0.0327,0.0344,0.563,"0/-","FAK inhibitor","PTK2","Kinase inhibitor"]
["PHF2","Pictilisib",-0.449,0.0245,0.257,0.336,2.13,0.0329,0.0346,0.563,"-/0","PI3K inhibitor, pan-class I","PIK3CA;PIK3CB;PIK3CG;PIK3CD;MTOR","Kinase inhibitor"]
["PSMC4","PAC_1",0.436,0.0293,-0.297,0.265,-2.21,0.0271,0.0293,0.563,"+/0","procaspase-3 activator","CASP3","Apoptotic modulator"]
["SCFD2","CUDC_305",0.32,0.119,-0.415,0.11,-2.21,0.0272,0.0294,0.563,"0/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["UXS1","Tipifarnib",-0.202,0.333,0.463,0.0712,2.02,0.0438,0.0427,0.563,"0/0","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["UQCRFS1","Methylprednisolone",-0.107,0.612,0.535,0.0327,2.01,0.0441,0.043,0.563,"0/+","Glucocorticoid, immunomodulatory agent","NR3C1","Immunomodulatory"]
["ZFAND5","Hydroxyurea",0.123,0.557,-0.523,0.0378,-2.01,0.0442,0.0431,0.563,"0/-","Antineoplastic agent","RRM1","Conv.Chemo"]
["CENPU","Doxorubicin",0.212,0.31,-0.479,0.0607,-2.1,0.0354,0.0375,0.564,"0/0","Topoisomerase II inhibitor","TOP2A;NOLC1","Conv.Chemo"]
["GID4","GSK2256098",0.468,0.0183,-0.193,0.474,-2.01,0.0445,0.0454,0.564,"+/0","FAK inhibitor","PTK2","Kinase inhibitor"]
["GALNT12","PF_00477736",0.228,0.273,-0.438,0.0895,-2.01,0.0448,0.0457,0.564,"0/0","CHEK1 inhibitor","CHEK1;KDR;FLT3;YES1;CHEK2","Kinase inhibitor"]
["FCGRT","ARV_825",0.331,0.106,-0.343,0.193,-2.01,0.0448,0.0457,0.564,"0/0","BET-targeting PROTAC","BRD4","Differentiating.epigenetic modifier"]
["KLHDC3","AZD3965",0.458,0.0214,-0.256,0.339,-2.16,0.0307,0.0319,0.564,"+/0","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["MBD2","Midostaurin",-0.352,0.0846,0.369,0.16,2.16,0.0309,0.0321,0.564,"0/0","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["PCDH9","Vorinostat",0.65,0.000438,0.0295,0.914,-2.13,0.0331,0.0347,0.564,"+/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["PKN3","Sabutoclax",-0.229,0.271,-0.752,0.000778,-2.13,0.0333,0.035,0.564,"0/-","pan Bcl-2 family inhibitor","BCL2;BCL2L1;MCL1;BCL2A1","Apoptotic modulator"]
["POLE","Raltitrexed",0.583,0.00223,-0.077,0.777,-2.13,0.0335,0.0351,0.564,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["PYCARD","Midostaurin",-0.326,0.112,0.407,0.118,2.2,0.0277,0.0299,0.564,"0/0","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["YPEL5","Clomifene",-0.221,0.287,0.445,0.0844,2.01,0.0444,0.0433,0.564,"0/0","Selective estrogen receptor modulator","ESR1;SHBG","Hormone therapy"]
["ZNF614","Vismodegib",-0.221,0.289,0.445,0.0843,2.01,0.0446,0.0435,0.564,"0/0","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["TRAF3IP2","Dactinomycin",-0.241,0.246,0.427,0.099,2.01,0.0448,0.0437,0.564,"0/0","RNA and DNA synthesis inhibitor","DNA","Conv.Chemo"]
["CCNB2","Bexarotene",0.216,0.3,-0.474,0.0634,-2.1,0.0357,0.0379,0.565,"0/0","Antineoplastic agent, retinoid specifically selective for retinoid X receptors","RXRA;RXRB","Differentiating.epigenetic modifier"]
["DPH3","Vinblastine",0.234,0.26,-0.459,0.0739,-2.1,0.0358,0.038,0.565,"0/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["HOOK2","Fulvestrant",0.435,0.0296,-0.23,0.391,-2,0.0452,0.0461,0.565,"+/0","Estrogen receptor antagonist","ESR1","Hormone therapy"]
["ERI1","Glasdegib",0.243,0.242,-0.423,0.103,-2,0.0456,0.0465,0.565,"0/0","Smo inhibitor","SMO","Hedgehog inhibitor"]
["GPS2","BAY_87_2243",-0.499,0.0112,0.15,0.58,2,0.0459,0.0467,0.565,"-/0","HIF1alpha inhibitor","HIF1A","Differentiating.epigenetic modifier"]
["HK1","Tozasertib",-0.301,0.144,0.37,0.159,2,0.0459,0.0468,0.565,"0/0","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["MFSD10","Prexasertib",-0.332,0.105,0.387,0.139,2.15,0.0314,0.0326,0.565,"0/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["HVCN1","Cladribine",-0.399,0.0485,0.319,0.229,2.15,0.0316,0.0328,0.565,"-/0","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["PLEKHG1","AZD_1080",-0.32,0.118,0.39,0.136,2.13,0.0335,0.0352,0.565,"0/0","GSK3 inhibitor","GSK3B;GSK3A","Kinase inhibitor"]
["MRPS9","A_1155463",-0.548,0.0046,0.126,0.641,2.12,0.0339,0.0355,0.565,"-/0","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2","Apoptotic modulator"]
["PRR14L","Indibulin",0.465,0.0192,-0.26,0.331,-2.2,0.0278,0.0301,0.565,"+/0","Mitoric inhibitor, Microtubule depolymerizer","TUBB","Conv.Chemo"]
["SCPEP1","Canertinib",0.298,0.148,-0.431,0.0953,-2.2,0.0279,0.0302,0.565,"0/0","Pan-HER inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["SEC16A","Docetaxel",-0.249,0.23,0.473,0.0644,2.2,0.0281,0.0303,0.565,"0/0","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["VIRMA","Onalespib",-0.402,0.0466,0.269,0.314,2.01,0.0449,0.0439,0.565,"-/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["ZBTB48","Pevonedistat",0.222,0.285,-0.442,0.0863,-2,0.045,0.0439,0.565,"0/0","NAE inhibitor","NAE1","Metabolic modifier"]
["ZNF580","OSU_03012",0.313,0.128,-0.36,0.171,-2,0.0454,0.0442,0.565,"0/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["ZNF397","A_1210477",0.237,0.254,-0.428,0.0978,-2,0.0455,0.0444,0.565,"0/0","MCL-1 inhibitor","MCL1","Apoptotic modulator"]
["EPHB6","E7820",0.239,0.25,-0.425,0.101,-2,0.046,0.0469,0.566,"0/0","Integrin alpha2 expression inhibitor","ITGA2","Other"]
["EIF2AK3","Exemestane",-0.0896,0.67,0.543,0.0299,1.99,0.0462,0.047,0.566,"0/+","Aromatase inhibitor","CYP19A1","Hormone therapy"]
["LMAN2","Prexasertib",-0.111,0.599,0.565,0.0227,2.15,0.0319,0.033,0.566,"0/+","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["MAFF","Onalespib",-0.332,0.105,0.384,0.142,2.14,0.032,0.0331,0.566,"0/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["MYBBP1A","Quizartinib",0.371,0.0675,-0.336,0.203,-2.12,0.0344,0.036,0.566,"0/0","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["RBIS","AT13148",0.366,0.0716,-0.365,0.165,-2.19,0.0285,0.0307,0.566,"0/0","p70S6K, PKA, ROCK (AKT) inhibitor","AKT1;AKT2;AKT3;RPS6KB1;ROCK1;ROCK2;PRKACA;PRKACB;PRKACG","Kinase inhibitor"]
["POLR3E","Cladribine",0.505,0.01,-0.207,0.442,-2.19,0.0285,0.0307,0.566,"+/0","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["RNF146","VS_4718",0.254,0.22,-0.466,0.0689,-2.19,0.0288,0.031,0.566,"0/0","FAK inhibitor","PTK2","Kinase inhibitor"]
["TYSND1","GDC_0084",0.358,0.0786,-0.313,0.239,-2,0.0459,0.0447,0.566,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["TWSG1","Vincristine",0.211,0.312,-0.449,0.0807,-2,0.046,0.0448,0.566,"0/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB;TUBA4A","Conv.Chemo"]
["EGLN1","Carboplatin",-0.168,0.423,0.51,0.0436,2.09,0.0364,0.0385,0.567,"0/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["COMMD5","LY3009120",0.0368,0.861,0.646,0.00689,2.09,0.0366,0.0388,0.567,"0/+","Pan-RAF, (Pan-HER inhibitor)","BRAF;RAF1","Kinase inhibitor"]
["FTO","Mitomycin_C",-0.273,0.187,-0.751,0.000792,-1.99,0.0466,0.0474,0.567,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["IFI27L2","Mitoxantrone",-0.487,0.0136,0.215,0.425,2.14,0.0321,0.0332,0.567,"-/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["MAP3K11","Finasteride",0.267,0.197,-0.442,0.0864,-2.14,0.0324,0.0335,0.567,"0/0","type II 5-alpha reductase inhibitor","SRD5A2","Hormone therapy"]
["IRF9","Tazemetostat",-0.23,0.269,0.473,0.0641,2.14,0.0325,0.0336,0.567,"0/0","EZH2 inhibitor","EZH2","Differentiating.epigenetic modifier"]
["PEX16","Midostaurin",0.137,0.514,-0.538,0.0318,-2.11,0.0348,0.0364,0.567,"0/-","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["RP2","NVP_BHG712",-0.424,0.0347,0.302,0.256,2.18,0.029,0.0312,0.567,"-/0","EphB4 inhibitor","EPHB4","Kinase inhibitor"]
["SAFB","Temsirolimus",0.117,0.576,-0.569,0.0215,-2.18,0.0291,0.0314,0.567,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["PSMD2","Vinorelbine",0.504,0.0102,-0.205,0.447,-2.18,0.0294,0.0316,0.567,"+/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["ZC3H3","Fluorouracil",0.406,0.0443,-0.26,0.33,-1.99,0.0464,0.0453,0.567,"+/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","TYMS","Conv.Chemo"]
["TRAPPC4","Docetaxel",-0.435,0.0296,0.226,0.4,1.99,0.0465,0.0453,0.567,"-/0","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["WDFY3","RO5126766",0.329,0.109,-0.34,0.197,-1.99,0.0467,0.0455,0.567,"0/0","dual RAF and MEK inhibitor","RAF1;BRAF;MAP2K1;MAP2K2","Kinase inhibitor"]
["CLASRP","C646",0.236,0.257,-0.454,0.0774,-2.09,0.037,0.0391,0.568,"0/0","EP300, CREB-binding protein (CBP) inhibitor","EP300","Differentiating.epigenetic modifier"]
["DNAL4","E7820",-0.523,0.00736,0.148,0.583,2.09,0.037,0.0392,0.568,"-/0","Integrin alpha2 expression inhibitor","ITGA2","Other"]
["CLK4","Saracatinib",-0.395,0.0507,0.301,0.257,2.08,0.0372,0.0394,0.568,"0/0","Src, ABL inhibitor","ABL1;SRC;LCK;YES1;LYN;FYN;BLK;EGFR;KIT;EPHA2","Kinase inhibitor"]
["GRN","Sirolimus",-0.493,0.0122,0.154,0.569,1.99,0.0468,0.0477,0.568,"-/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["MIIP","Binimetinib",0.13,0.534,-0.548,0.0279,-2.14,0.0327,0.0339,0.568,"0/-","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["LNPK","Vismodegib",-0.111,0.596,0.561,0.0237,2.13,0.0328,0.034,0.568,"0/+","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["MAN2A2","AZD_5438",-0.481,0.0149,0.217,0.419,2.13,0.0332,0.0343,0.568,"-/0","CDK1, 2, 9 inhibitor","CDK1;CDK2;CDK9","Kinase inhibitor"]
["NDUFAF2","Danusertib",0.148,0.48,-0.528,0.0354,-2.11,0.0351,0.0368,0.568,"0/-","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["NHP2","PD0325901",-0.11,0.6,0.555,0.0256,2.1,0.0353,0.0369,0.568,"0/+","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["NSL1","Rucaparib",0.495,0.0119,-0.191,0.479,-2.1,0.0355,0.0371,0.568,"+/0","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["NUDCD1","Masitinib",0.417,0.0381,-0.283,0.288,-2.1,0.0356,0.0373,0.568,"+/0","KIT inhibitor","KIT","Kinase inhibitor"]
["RCN1","Milciclib",0.273,0.186,-0.447,0.0829,-2.18,0.0296,0.0319,0.568,"0/0","CDK2 inhibitor","CDK2;CDK4;CDK5;CDK7;NTRK1","Kinase inhibitor"]
["PSMD6","IOX_2",-0.0668,0.751,-0.679,0.00384,-2.17,0.0298,0.0321,0.568,"0/-","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["UAP1","Milciclib",0.267,0.197,-0.399,0.126,-1.99,0.0468,0.0457,0.568,"0/0","CDK2 inhibitor","CDK2;CDK4;CDK5;CDK7;NTRK1","Kinase inhibitor"]
["ZGPAT","Mercaptopurine",-0.00353,0.987,-0.603,0.0134,-1.99,0.0471,0.0458,0.568,"0/-","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["TRIP6","Ralimetinib",0.445,0.0257,-0.211,0.432,-1.98,0.0474,0.0461,0.568,"+/0","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["WDFY2","PF_04708671",-0.504,0.0102,0.138,0.611,1.98,0.0476,0.0462,0.568,"-/0","p70S6K inhibitor","RPS6KB1","Kinase inhibitor"]
["CEP44","Abexinostat",-0.362,0.0752,0.335,0.204,2.08,0.0374,0.0397,0.569,"0/0","HDAC1 selective inhibitor","HDAC1","Differentiating.epigenetic modifier"]
["CDKN1B","Deferoxamine",-0.207,0.321,0.475,0.0627,2.08,0.0378,0.04,0.569,"0/0","Iron chelator","APP","Other"]
["CHN1","Bosutinib",0.26,0.21,-0.43,0.0964,-2.07,0.038,0.0402,0.569,"0/0","ABL, Src inhibitor","ABL1;LYN;HCK;SRC;EPHB2;NTRK1;NTRK2;TXK","Kinase inhibitor"]
["CEP250","Mubritinib",-0.29,0.16,0.403,0.121,2.07,0.038,0.0402,0.569,"0/0","HER2 inhibitor","ERBB2","Kinase inhibitor"]
["GAPVD1","GSK_690693",0.0162,0.939,0.611,0.0119,1.98,0.0472,0.0481,0.569,"0/+","AKT, PKA, PKC inhibitor","AKT1;AKT2;AKT3;PRKCE;PRKCB;PRKCD;PRKCH;PRKCQ;PRKX;PRKG1","Kinase inhibitor"]
["GIMAP8","Seliciclib",0.411,0.041,-0.251,0.349,-1.98,0.0474,0.0484,0.569,"+/0","CDK2, 7, 9 inhibitor","CDK2;CDK1;CDK5;MAPK1;MAPK3","Kinase inhibitor"]
["GM2A","Ridaforolimus",-0.244,0.24,0.417,0.108,1.98,0.0476,0.0485,0.569,"0/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["FBXO6","Enzalutamide",0.0727,0.73,-0.551,0.0271,-1.98,0.0479,0.0487,0.569,"0/-","AR antagonist","AR","Hormone therapy"]
["EXOC8","TGR_1202",-0.57,0.00295,0.0443,0.871,1.98,0.0481,0.049,0.569,"-/0","PI3Kdelta inhibitor","PIK3CD","Kinase inhibitor"]
["ITGA5","Ridaforolimus",-0.317,0.123,0.394,0.131,2.13,0.0334,0.0345,0.569,"0/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["NOP14","Foretinib",0.26,0.21,-0.437,0.0907,-2.1,0.0359,0.0375,0.569,"0/0","MET, VEGFR2 inhibitor","MET;KDR","Kinase inhibitor"]
["P4HA1","Axitinib",0.543,0.00505,-0.124,0.646,-2.1,0.0361,0.0376,0.569,"+/0","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["NOC3L","LY_2874455",0.39,0.0541,-0.31,0.242,-2.09,0.0363,0.0379,0.569,"0/0","FGFR inhibitor","FGFR1;FGFR2;FGFR3","Kinase inhibitor"]
["POP7","Tivozanib",0.446,0.0254,-0.272,0.307,-2.17,0.03,0.0322,0.569,"+/0","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["RPP14","Vorinostat",-0.463,0.0198,0.252,0.347,2.17,0.0302,0.0325,0.569,"-/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["PPIA","Vinflunine",-0.403,0.046,0.319,0.229,2.16,0.0304,0.0327,0.569,"-/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["SENP7","Merestinib",-0.528,0.00666,0.166,0.538,2.16,0.0308,0.033,0.569,"-/0","MET inhibitor","MET","Kinase inhibitor"]
["POLR3C","A_1331852",-0.555,3.98E-3,0.129,0.634,2.16,0.0309,0.033,0.569,"-/0","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2;MCL1","Apoptotic modulator"]
["UBAP2L","Raltitrexed",0.718,{"v":5.26e-05,"d":"5.26E-05"},0.209,0.438,-1.98,0.0478,0.0465,0.569,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["DENND11","ODM_201",-0.349,0.0875,0.346,0.189,2.07,0.0382,0.0404,0.57,"0/0","AR antagonist","AR","Hormone therapy"]
["CD84","Cytarabine.Idarubicin",0.202,0.332,0.73,1.33E-3,2.07,0.0386,0.0408,0.57,"0/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["ERCC6L2","Valrubicin",0.622,0.000893,0.0377,0.89,-1.98,0.0482,0.0491,0.57,"+/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["GNG2","Tubacin",-0.245,0.238,0.414,0.111,1.97,0.0485,0.0493,0.57,"0/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["EIF4A2","Vinflunine",-0.115,0.583,0.518,0.0397,1.97,0.0487,0.0495,0.57,"0/+","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["IPMK","Selinexor",0.208,0.319,-0.487,0.0559,-2.12,0.0338,0.0349,0.57,"0/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["NOP14","Fostamatinib",0.233,0.261,-0.457,0.0751,-2.09,0.0365,0.0381,0.57,"0/0","SYK inhibitor","SYK","Kinase inhibitor"]
["PINX1","Everolimus",0.401,0.0467,-0.297,0.265,-2.09,0.0366,0.0382,0.57,"+/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["RPS13","IOX_2",0.273,0.187,-0.441,0.0872,-2.15,0.0313,0.0335,0.57,"0/0","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["RFFL","RO5126766",-0.338,0.0986,0.38,0.146,2.15,0.0316,0.0338,0.57,"0/0","dual RAF and MEK inhibitor","RAF1;BRAF;MAP2K1;MAP2K2","Kinase inhibitor"]
["RRAS2","Clomifene",-0.397,0.0496,0.32,0.227,2.15,0.0317,0.034,0.57,"-/0","Selective estrogen receptor modulator","ESR1;SHBG","Hormone therapy"]
["ZNF281","Amsacrine",0.426,0.0336,-0.232,0.387,-1.98,0.048,0.0468,0.57,"+/0","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["ZEB2","Tubastatin_A",0.245,0.238,-0.414,0.111,-1.97,0.0484,0.0471,0.57,"0/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["UBXN7","CC_223",0.23,0.269,-0.427,0.0994,-1.97,0.0486,0.0473,0.57,"0/0","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["DDX59","NVP_BHG712",0.243,0.243,-0.443,0.0859,-2.07,0.0387,0.0409,0.571,"0/0","EphB4 inhibitor","EPHB4","Kinase inhibitor"]
["CDIPT","WEHI_539",0.256,0.217,-0.431,0.0958,-2.07,0.0389,0.0411,0.571,"0/0","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["HSDL1","A_1331852",0.441,0.0275,-0.213,0.428,-1.97,0.0488,0.0496,0.571,"+/0","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2;MCL1","Apoptotic modulator"]
["FBXL20","WEHI_539",0.327,0.111,-0.336,0.203,-1.97,0.0489,0.0497,0.571,"0/0","Bcl-XL inhibitor","BCL2L1","Apoptotic modulator"]
["FAM133B","Alisertib",0.217,0.298,-0.437,0.0909,-1.97,0.0491,0.0499,0.571,"0/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["ILF3","Mocetinostat",-0.303,0.141,0.405,0.12,2.12,0.0339,0.0351,0.571,"0/0","HDAC inhibitor (HDAC1 and 2-selective)","HDAC1;HDAC2;HDAC3;HDAC11","Differentiating.epigenetic modifier"]
["LENG1","Ganetespib",0.129,0.538,-0.545,0.029,-2.12,0.0341,0.0352,0.571,"0/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["NSMCE4A","Binimetinib",0.0748,0.722,-0.575,0.0197,-2.09,0.0368,0.0385,0.571,"0/-","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["MRTO4","Eribulin",0.345,0.091,-0.354,0.179,-2.09,0.037,0.0386,0.571,"0/0","Mitotic inhibitor, microtubule depolymerizer","TUBB1","Conv.Chemo"]
["PARVB","Luminespib",-0.113,0.592,0.548,0.028,2.08,0.0373,0.0389,0.571,"0/+","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["PSTPIP2","Marimastat",0.312,0.129,-0.403,0.122,-2.14,0.032,0.0342,0.571,"0/0","MMP-9, MMP-1, MMP-2, MMP-14, MMP-7 inhibitor","MMP1;MMP2;MMP9;MMP7;MMP14","Other"]
["RPS6KB1","Amuvatinib",-0.376,0.0638,0.34,0.198,2.14,0.0321,0.0343,0.571,"0/0","Broad TK inhibitor","KIT;PDGFRA;FLT3","Kinase inhibitor"]
["SCNM1","Onalespib",0.173,0.409,-0.518,0.0396,-2.14,0.0323,0.0345,0.571,"0/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["PRKD2","UCN_01",-0.137,0.513,0.544,0.0294,2.14,0.0325,0.0347,0.571,"0/+","PKCbeta, PDK1, Chk, Cdk2 inhibitor","PRKCB;PDPK1","Kinase inhibitor"]
["SEC14L1","Galiellalactone",0.352,0.0846,-0.362,0.168,-2.14,0.0328,0.0349,0.571,"0/0","STAT3-DNA interaction inhibitor","STAT3","Other"]
["TRMT10B","Ibrutinib",0.0346,0.87,-0.575,0.0198,-1.97,0.0488,0.0475,0.571,"0/-","BTK inhibitor","BTK;BLK;EGFR;FYN;LYN;LCK;BRAF;WNK1","Kinase inhibitor"]
["TSC22D3","AZD_6482",-0.117,0.578,0.516,0.0406,1.97,0.049,0.0476,0.571,"0/+","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["WDR74","Clomifene",0.208,0.318,-0.444,0.0851,-1.97,0.0492,0.0478,0.571,"0/0","Selective estrogen receptor modulator","ESR1;SHBG","Hormone therapy"]
["ZNF302","Niraparib",0.14,0.504,0.68,0.00377,1.97,0.0494,0.048,0.571,"0/+","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["CNPY2","Tasquinimod",-0.596,0.00168,0.034,0.901,2.06,0.0394,0.0416,0.572,"-/0","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["EXOC4","TGX_221",-0.562,3.48E-3,0.0528,0.846,1.97,0.0492,0.05,0.572,"-/0","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["H2AX","Marimastat",-0.159,0.448,-0.69,0.00311,-1.96,0.0494,0.0503,0.572,"0/-","MMP-9, MMP-1, MMP-2, MMP-14, MMP-7 inhibitor","MMP1;MMP2;MMP9;MMP7;MMP14","Other"]
["GCFC2","Masitinib",0.0969,0.645,-0.529,0.0351,-1.96,0.0499,0.0507,0.572,"0/-","KIT inhibitor","KIT","Kinase inhibitor"]
["MLYCD","Litronesib",-0.211,0.312,0.482,0.0588,2.11,0.0345,0.0357,0.572,"0/0","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["KCNN4","Givinostat",-0.467,0.0187,0.229,0.394,2.11,0.0348,0.0359,0.572,"-/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC10","Differentiating.epigenetic modifier"]
["PABPC1","ML390",0.498,0.0113,-0.18,0.505,-2.08,0.0373,0.039,0.572,"+/0","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["NUP85","Tipifarnib",-0.225,0.28,0.461,0.0722,2.08,0.0376,0.0392,0.572,"0/0","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["NDUFA5","Nelarabine",-0.0921,0.661,0.561,0.0237,2.08,0.0377,0.0394,0.572,"0/+","Antimetabolite, Nucleoside analog, DNA, RNA synth inhibitor","DNA","Conv.Chemo"]
["NDEL1","Ivosidenib",-0.509,0.00942,0.164,0.544,2.08,0.0378,0.0395,0.572,"-/0","IDH1 R132H and R132C inhibitor","IDH1","Differentiating.epigenetic modifier"]
["MSANTD4","Tucidinostat",0.372,0.0671,-0.323,0.223,-2.07,0.0382,0.0397,0.572,"0/0","HDAC1, 2, 3 and 10 inhibitor","HDAC1;HDAC2;HDAC3;HDAC10","Differentiating.epigenetic modifier"]
["P4HB","Doxorubicin",-0.261,0.208,0.428,0.0983,2.07,0.0385,0.04,0.572,"0/0","Topoisomerase II inhibitor","TOP2A;NOLC1","Conv.Chemo"]
["PSMA7","Danusertib",-0.0601,0.775,-0.668,0.00472,-2.13,0.0329,0.0351,0.572,"0/-","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["TUBB","Fulvestrant",-0.139,0.509,0.499,0.0493,1.96,0.0495,0.0482,0.572,"0/+","Estrogen receptor antagonist","ESR1","Hormone therapy"]
["TRIM8","Enzalutamide",0.303,0.142,-0.357,0.174,-1.96,0.0499,0.0485,0.572,"0/0","AR antagonist","AR","Hormone therapy"]
["CEP162","Molibresib",0.023,0.913,0.631,0.00878,2.06,0.0396,0.0417,0.573,"0/+","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["DDB2","Olaparib",0.0381,0.857,0.639,0.00767,2.05,0.0399,0.0421,0.573,"0/+","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["MGST3","Binimetinib",-0.375,0.0649,0.33,0.211,2.11,0.0351,0.0362,0.573,"0/0","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["PI4K2A","Fludarabine",0.37,0.0689,-0.323,0.223,-2.07,0.0389,0.0404,0.573,"0/0","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["NEU1","Miltefosine",-0.146,0.486,0.519,0.0394,2.06,0.039,0.0405,0.573,"0/+","Antimicrobial, inhibits PI3K and AKT","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Other"]
["POP1","Azacitidine",0.319,0.121,-0.393,0.132,-2.13,0.0332,0.0354,0.573,"0/0","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["PRIMPOL","THZ2",0.245,0.238,-0.458,0.0745,-2.13,0.0333,0.0355,0.573,"0/0","CDK7 inhibitor","CDK7","Kinase inhibitor"]
["RSL24D1","BI_2536",0.476,0.0162,-0.222,0.408,-2.13,0.0336,0.0357,0.573,"+/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["DMAC1","Volasertib",-0.162,0.439,0.504,0.0465,2.05,0.0401,0.0422,0.574,"0/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["CHST12","Fludarabine",0.287,0.165,-0.399,0.126,-2.05,0.0402,0.0424,0.574,"0/0","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["ITIH2","Bleomycin",-0.187,0.37,0.498,0.0497,2.1,0.0354,0.0365,0.574,"0/+","Glycopeptide antibiotic, causes DNA breaks","DNA","Conv.Chemo"]
["IDH3G","Vincristine",-0.485,0.0141,0.203,0.452,2.1,0.0358,0.0368,0.574,"-/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB;TUBA4A","Conv.Chemo"]
["NOP16","GSK_461364",0.435,0.0296,-0.249,0.353,-2.06,0.0395,0.0409,0.574,"+/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["PMM2","Dactolisib",-0.214,0.305,0.465,0.0698,2.06,0.0395,0.041,0.574,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;ATR;RPS6KB1","Kinase inhibitor"]
["POLR3E","Cytarabine",0.31,0.132,-0.398,0.127,-2.12,0.0341,0.0362,0.574,"0/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","POLB;DNA","Conv.Chemo"]
["CTPS1","Ridaforolimus",-0.0793,0.706,-0.662,0.00526,-2.05,0.0407,0.0429,0.575,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["KMT5A","VER_155008",0.348,0.0882,-0.354,0.178,-2.1,0.036,0.037,0.575,"0/0","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["NFXL1","Perifosine",-0.0549,0.794,0.582,0.0181,2.06,0.0396,0.0412,0.575,"0/+","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["SAAL1","GSK_690693",0.406,0.0438,-0.3,0.259,-2.12,0.0342,0.0363,0.575,"+/0","AKT, PKA, PKC inhibitor","AKT1;AKT2;AKT3;PRKCE;PRKCB;PRKCD;PRKCH;PRKCQ;PRKX;PRKG1","Kinase inhibitor"]
["RCL1","Mercaptopurine",0.361,0.0761,-0.347,0.188,-2.12,0.0343,0.0365,0.575,"0/0","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["COA7","CCT196969",0.211,0.312,-0.463,0.0708,-2.04,0.0409,0.0431,0.576,"0/0","pan-RAF, Src inhibitor","RAF1;BRAF;SRC;LCK","Kinase inhibitor"]
["CNN2","Selinexor",-0.552,0.0042,0.0928,0.733,2.04,0.041,0.0433,0.576,"-/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["COQ5","8_amino_adenosine",-0.391,0.0534,0.292,0.272,2.04,0.0413,0.0435,0.576,"0/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["MED16","Verdinexor",-0.474,0.0166,0.213,0.428,2.09,0.0364,0.0374,0.576,"-/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["IPO7","CPI_0610",-0.261,0.208,0.434,0.0929,2.09,0.0364,0.0375,0.576,"0/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["NDUFAF6","Topotecan",0.251,0.226,-0.432,0.0951,-2.05,0.04,0.0416,0.576,"0/0","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["PEX26","Erastin",-0.22,0.291,0.457,0.0752,2.05,0.0405,0.0419,0.576,"0/0","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["PAXIP1","Selinexor",0.389,0.0544,-0.297,0.265,-2.05,0.0405,0.042,0.576,"0/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["PAIP2B","Venetoclax",0.198,0.344,-0.474,0.0635,-2.05,0.0408,0.0422,0.576,"0/0","Bcl-2 selective inhibitor","BCL2","Apoptotic modulator"]
["PPP1R37","Clomifene",-0.133,0.525,0.541,0.0306,2.11,0.0346,0.0368,0.576,"0/+","Selective estrogen receptor modulator","ESR1;SHBG","Hormone therapy"]
["POLM","Saracatinib",0.317,0.122,-0.388,0.137,-2.11,0.0348,0.037,0.576,"0/0","Src, ABL inhibitor","ABL1;SRC;LCK;YES1;LYN;FYN;BLK;EGFR;KIT;EPHA2","Kinase inhibitor"]
["DOK1","Raltitrexed",-0.189,0.365,0.479,0.0605,2.04,0.0415,0.0437,0.577,"0/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["CD5","MK_2206",-0.238,0.251,0.437,0.0902,2.04,0.0418,0.044,0.577,"0/0","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["HYPK","Dabrafenib",0.218,0.295,-0.47,0.0665,-2.09,0.0367,0.0377,0.577,"0/0","BRAF(V600E) inhibitor","BRAF;RAF1","Kinase inhibitor"]
["IGSF3","AR_42",0.541,0.00522,-0.124,0.647,-2.09,0.0368,0.0378,0.577,"+/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["NEDD4L","Encorafenib",-0.199,0.34,0.472,0.0647,2.04,0.0409,0.0424,0.577,"0/0","BRAF(V600E) inhibitor","BRAF;RAF1","Kinase inhibitor"]
["NKAPD1","BMS_911543",0.305,0.139,-0.38,0.147,-2.04,0.0411,0.0426,0.577,"0/0","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["PPP1R2","Amsacrine",0.319,0.121,-0.386,0.14,-2.11,0.0351,0.0372,0.577,"0/0","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["SELENOO","BMS_911543",-0.3,0.144,0.402,0.123,2.1,0.0354,0.0375,0.577,"0/0","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["CD1B","Pevonedistat",-0.12,0.567,-0.682,3.64E-3,-2.03,0.042,0.0442,0.578,"0/-","NAE inhibitor","NAE1","Metabolic modifier"]
["MBNL1","Clomifene",0.352,0.0845,0.8,2.02E-4,2.09,0.037,0.038,0.578,"0/+","Selective estrogen receptor modulator","ESR1;SHBG","Hormone therapy"]
["MFSD1","Pexidartinib",-0.0855,0.684,0.567,0.0221,2.08,0.0374,0.0384,0.578,"0/+","KIT, CSF1R, FLT3 inhibitor","CSF1R;FLT3;KIT","Kinase inhibitor"]
["NFAT5","ONX_0914",-0.253,0.222,0.425,0.101,2.04,0.0416,0.0431,0.578,"0/0","LMP7 (immunoproteasome)","PSMB8","Protease.proteasome inhibitor"]
["PLA2G15","Topotecan",-0.373,0.0661,0.31,0.243,2.04,0.0417,0.0431,0.578,"0/0","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["PRICKLE3","Carfilzomib",-0.311,0.13,0.392,0.133,2.1,0.0355,0.0377,0.578,"0/0","Proteasome inhibitor (20S subunit)","PSMB5;PSMB8;PSMB1;PSMB2;PSMB9;PSMB10","Protease.proteasome inhibitor"]
["CLYBL","AMG319",-0.107,0.611,0.539,0.0312,2.03,0.0423,0.0445,0.579,"0/+","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["CEP192","Amsacrine",0.224,0.282,-0.448,0.0816,-2.03,0.0424,0.0445,0.579,"0/0","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["IVD","Gandotinib",-0.0379,0.857,0.598,0.0144,2.08,0.0375,0.0385,0.579,"0/+","JAK2 inhibitor","JAK2;JAK1;FLT3;FLT4;FGFR2;TYK2;NTRK2;FGFR3;KDR;ALK","Kinase inhibitor"]
["POLK","Ribociclib",-0.298,0.148,0.383,0.143,2.03,0.042,0.0434,0.579,"0/0","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["NKTR","CPI_0610",0.219,0.293,-0.453,0.078,-2.03,0.0421,0.0435,0.579,"0/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["PSMD9","Tivantinib",-0.484,0.0142,0.204,0.45,2.1,0.0357,0.0379,0.579,"-/0","MET inhibitor","MET","Kinase inhibitor"]
["CHMP6","Foretinib",-0.00471,0.982,0.607,0.0126,2.03,0.0426,0.0448,0.58,"0/+","MET, VEGFR2 inhibitor","MET;KDR","Kinase inhibitor"]
["CYC1","Enzalutamide",0.192,0.357,-0.473,0.0642,-2.03,0.0428,0.0449,0.58,"0/0","AR antagonist","AR","Hormone therapy"]
["MCTP2","Temsirolimus",0.0626,0.766,0.658,0.00559,2.08,0.0378,0.0388,0.58,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["KCTD1","CUDC_305",-0.256,0.217,0.433,0.0938,2.07,0.0381,0.0391,0.58,"0/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["LSM4","Tacrolimus",0.022,0.917,-0.606,0.0128,-2.07,0.0382,0.0392,0.58,"0/-","binds FKBP12, causes inhibition of calcineurin","FKBP1A","Rapalog"]
["NOP53","Bosutinib",0.213,0.306,-0.457,0.0752,-2.03,0.0424,0.0438,0.58,"0/0","ABL, Src inhibitor","ABL1;LYN;HCK;SRC;EPHB2;NTRK1;NTRK2;TXK","Kinase inhibitor"]
["PAIP2B","Mocetinostat",0.212,0.31,-0.457,0.0749,-2.03,0.0428,0.0442,0.58,"0/0","HDAC inhibitor (HDAC1 and 2-selective)","HDAC1;HDAC2;HDAC3;HDAC11","Differentiating.epigenetic modifier"]
["NUDT9","ABT_751",0.372,0.0671,-0.307,0.247,-2.03,0.0428,0.0442,0.58,"0/0","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["PPM1A","Cytarabine.Idarubicin",-0.537,0.00563,0.133,0.624,2.1,0.036,0.0381,0.58,"-/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["QTRT1","Ipatasertib",0.13,0.535,-0.538,0.0316,-2.09,0.0363,0.0384,0.58,"0/-","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["RAB20","Fluorouracil",-0.196,0.347,0.488,0.0551,2.09,0.0363,0.0384,0.58,"0/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","TYMS","Conv.Chemo"]
["CLK4","Tasquinimod",-0.271,0.19,0.405,0.12,2.02,0.0432,0.0454,0.581,"0/0","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["KAT6B","BMS_754807",-0.0717,0.733,0.573,0.0203,2.07,0.0385,0.0395,0.581,"0/+","IGF1R inhibitor","IGF1R","Kinase inhibitor"]
["INTS2","CC_115",0.246,0.237,-0.44,0.0877,-2.07,0.0386,0.0396,0.581,"0/0","mTOR, DNA-PK inhibitor","MTOR;PIK3CA;PRKDC","Kinase inhibitor"]
["MTMR12","Dabrafenib",-0.185,0.376,0.478,0.0612,2.02,0.0432,0.0445,0.581,"0/0","BRAF(V600E) inhibitor","BRAF;RAF1","Kinase inhibitor"]
["MRPS22","Marimastat",-0.153,0.464,0.502,0.0477,2.02,0.0435,0.0448,0.581,"0/+","MMP-9, MMP-1, MMP-2, MMP-14, MMP-7 inhibitor","MMP1;MMP2;MMP9;MMP7;MMP14","Other"]
["MTMR14","Paclitaxel",-0.524,0.00716,0.124,0.649,2.02,0.0435,0.0449,0.581,"-/0","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["RRP12","Prednisolone",0.244,0.24,-0.448,0.0819,-2.09,0.0366,0.0388,0.581,"0/0","Glucocorticoid, immunomodulatory agent","NR3C1","Immunomodulatory"]
["SCRN1","Fulvestrant",0.149,0.476,-0.522,0.0379,-2.09,0.0369,0.0391,0.581,"0/-","Estrogen receptor antagonist","ESR1","Hormone therapy"]
["SARDH","Tacedinaline",-0.0278,0.895,0.605,0.0129,2.09,0.037,0.0392,0.581,"0/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["DIPK2A","Sotrastaurin",-0.21,0.313,0.456,0.076,2.02,0.0437,0.0459,0.582,"0/0","PKC inhibitor","PRKCB;PRKCQ;PRKCH;PRKCA;PRKCE;PRKCA","Kinase inhibitor"]
["MOSPD2","Gilteritinib",0.426,0.0339,-0.261,0.329,-2.06,0.0391,0.0401,0.582,"+/0","FLT3, AXL inhibitor","FLT3","Kinase inhibitor"]
["MVD","Megestrol_acetate",-0.234,0.26,0.436,0.0914,2.02,0.0437,0.045,0.582,"0/0","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["MYO1C","BMS_911543",-0.176,0.399,0.483,0.0583,2.01,0.044,0.0453,0.582,"0/0","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["PRELID3B","Sitravatinib",0.142,0.497,-0.527,0.036,-2.08,0.0372,0.0393,0.582,"0/-","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["PSMG2","Pacritinib",-0.147,0.484,0.523,0.0377,2.08,0.0374,0.0395,0.582,"0/+","FLT3, JAK2 inhibitor","FLT3;JAK2;TYK2","Kinase inhibitor"]
["PRR14L","Imiquimod",0.131,0.534,-0.534,0.033,-2.08,0.0376,0.0397,0.582,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["MAFF","IOX_1",-0.203,0.331,0.474,0.0635,2.06,0.0392,0.0402,0.583,"0/0","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["LRRC1","C646",0.335,0.102,-0.356,0.176,-2.06,0.0393,0.0403,0.583,"0/0","EP300, CREB-binding protein (CBP) inhibitor","EP300","Differentiating.epigenetic modifier"]
["MRPL49","GSK923295",-0.169,0.419,0.5,0.0486,2.06,0.0396,0.0405,0.583,"0/+","CENP-E inhibitor","CENPE","Kinesin inhibitor"]
["PDLIM7","Azacitidine",0.31,0.132,-0.365,0.164,-2.01,0.0443,0.0456,0.583,"0/0","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["RSL1D1","Cerdulatinib",0.427,0.0331,-0.264,0.324,-2.08,0.0378,0.0399,0.583,"+/0","JAK, SYK inhibitor","JAK1;JAK2;JAK3;TYK2;SYK","Kinase inhibitor"]
["PPP4R2","SB743921",0.566,0.00318,-0.0849,0.755,-2.08,0.0378,0.04,0.583,"+/0","Mitotic inhibitor, Eg5, KSP inhibitor","KIF11","Kinesin inhibitor"]
["SEC23A","Altiratinib",-0.0362,0.864,0.597,0.0146,2.07,0.0382,0.0403,0.583,"0/+","MET, Tie-2 inhibitor","MET;NTRK1;NTRK3;NTRK2;TEK;FLT3;KIT;KDR","Kinase inhibitor"]
["SDE2","BX_912",0.367,0.0713,-0.327,0.216,-2.07,0.0384,0.0405,0.583,"0/0","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["CMTR1","Fludarabine",-0.457,0.0218,0.208,0.44,2.01,0.0443,0.0465,0.584,"-/0","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["LIME1","Itraconazole",0.233,0.262,-0.448,0.082,-2.06,0.0398,0.0408,0.584,"0/0","antifungal, hedgehog signaling inhibitor","CYP51A1;CYP3A4","Other"]
["MT-ATP8","Triapine",-0.456,0.0219,0.207,0.442,2.01,0.0447,0.046,0.584,"-/0","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["PALM2AKAP2","AT_101",0.0949,0.652,-0.542,0.0302,-2.01,0.0449,0.0462,0.584,"0/-","pan Bcl-2 family inhibitor","BCL2;BCL2L1;MCL1","Apoptotic modulator"]
["NAGLU","NVP_BGT226",-0.345,0.0909,0.328,0.215,2,0.0451,0.0464,0.584,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CG;MTOR","Kinase inhibitor"]
["RUFY3","Volasertib",-0.412,0.0407,0.278,0.297,2.07,0.0386,0.0407,0.584,"-/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["DSCC1","Fulvestrant",-0.243,0.241,0.426,0.0998,2.01,0.0444,0.0466,0.585,"0/0","Estrogen receptor antagonist","ESR1","Hormone therapy"]
["CD1A","Idelalisib",0.32,0.119,-0.355,0.178,-2.01,0.0447,0.0469,0.585,"0/0","PI3K inhibitor, p110-selective","PIK3CD","Kinase inhibitor"]
["DDX20","BMS863233",0.0699,0.74,-0.559,0.0243,-2.01,0.0448,0.047,0.585,"0/-","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["MIS12","Copanlisib",-0.331,0.105,0.357,0.175,2.05,0.0402,0.0411,0.585,"0/0","PI3K alpha, delta selective inhibitor","PIK3CA;PIK3CB;PIK3CG;PIK3CD","Kinase inhibitor"]
["IL27RA","Decitabine",0.00383,0.986,0.617,0.0109,2.05,0.0406,0.0415,0.585,"0/+","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["NCKAP1","Mercaptopurine",0.219,0.293,-0.444,0.0846,-2,0.0454,0.0466,0.585,"0/0","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["NUMB","OTS167",-0.228,0.273,0.436,0.0912,2,0.0455,0.0468,0.585,"0/0","MELK inhibitor","MELK","Kinase inhibitor"]
["PRAG1","Thioguanine",-0.247,0.234,0.438,0.0896,2.06,0.0389,0.0411,0.585,"0/0","Antimetabolite, Purine analog","DNMT1","Conv.Chemo"]
["RAB20","Varlitinib",-0.468,0.0184,0.211,0.432,2.06,0.0392,0.0413,0.585,"-/0","EGFR HER2 inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["DDX51","Cerdulatinib",0.327,0.11,-0.347,0.188,-2.01,0.045,0.0472,0.586,"0/0","JAK, SYK inhibitor","JAK1;JAK2;JAK3;TYK2;SYK","Kinase inhibitor"]
["DGKD","GDC_0084",-0.25,0.229,0.418,0.107,2,0.0452,0.0474,0.586,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["CTU2","E7820",0.272,0.188,-0.398,0.127,-2,0.0454,0.0476,0.586,"0/0","Integrin alpha2 expression inhibitor","ITGA2","Other"]
["LMF2","AZD_6482",-0.348,0.0881,0.339,0.2,2.05,0.0407,0.0416,0.586,"0/0","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["MED16","GSK_461364",-0.183,0.382,0.485,0.0567,2.04,0.041,0.0419,0.586,"0/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["MVD","Ribociclib",0.159,0.446,-0.492,0.0531,-2,0.0457,0.0469,0.586,"0/0","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["PAQR7","Triapine",-0.344,0.0926,0.328,0.216,2,0.0459,0.0472,0.586,"0/0","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["MTMR4","Capmatinib",-0.0109,0.959,0.596,0.0148,1.99,0.0461,0.0473,0.586,"0/+","MET inhibitor","MET","Kinase inhibitor"]
["PPP1R3F","A_1210477",0.118,0.573,-0.538,0.0315,-2.06,0.0394,0.0416,0.586,"0/-","MCL-1 inhibitor","MCL1","Apoptotic modulator"]
["RAB20","Afuresertib",-0.444,0.026,0.238,0.376,2.06,0.0396,0.0417,0.586,"-/0","AKT1-selective inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["CORO1A","Tubacin",0.00714,0.973,0.608,0.0124,2,0.0458,0.048,0.587,"0/+","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["CRIM1","GSK_1070916",-0.219,0.292,0.443,0.086,2,0.0458,0.048,0.587,"0/0","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["MBLAC2","Palomid_529",-0.017,0.936,0.602,0.0135,2.04,0.0413,0.0422,0.587,"0/+","AKT, MTOR, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3;MTOR","Kinase inhibitor"]
["KCTD10","Vincristine",0.419,0.0373,-0.261,0.328,-2.04,0.0414,0.0424,0.587,"+/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB;TUBA4A","Conv.Chemo"]
["OTUD3","Finasteride",-0.391,0.053,0.275,0.302,1.99,0.0466,0.0478,0.587,"0/0","type II 5-alpha reductase inhibitor","SRD5A2","Hormone therapy"]
["NADK","Taladegib",-0.111,0.596,0.526,0.0366,1.99,0.0467,0.048,0.587,"0/+","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["MTF1","Cabozantinib",0.314,0.126,-0.354,0.179,-1.99,0.0469,0.0481,0.587,"0/0","VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor","KDR;MET;FLT3;KIT;RET;TEK","Kinase inhibitor"]
["RLF","Decitabine",0.378,0.0626,-0.311,0.242,-2.05,0.0399,0.0421,0.587,"0/0","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["RALA","Copanlisib",0.158,0.452,-0.507,0.0451,-2.05,0.0403,0.0425,0.587,"0/-","PI3K alpha, delta selective inhibitor","PIK3CA;PIK3CB;PIK3CG;PIK3CD","Kinase inhibitor"]
["EHMT1","Carboplatin",0.513,8.77E-3,-0.13,0.631,-1.99,0.0462,0.0483,0.588,"+/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["KIFAP3","Methotrexate",-0.266,0.199,0.414,0.111,2.04,0.0415,0.0425,0.588,"0/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["MIGA2","Imiquimod",-0.25,0.228,0.427,0.0988,2.04,0.0418,0.0427,0.588,"0/0","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["IPO7","ABT_751",0.606,1.31E-3,-0.00799,0.977,-2.03,0.0421,0.043,0.588,"+/0","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["NOC4L","Topotecan",0.391,0.053,-0.274,0.305,-1.99,0.0471,0.0483,0.588,"0/0","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["PAK4","GSK_690693",0.407,0.0436,-0.256,0.339,-1.98,0.0474,0.0486,0.588,"+/0","AKT, PKA, PKC inhibitor","AKT1;AKT2;AKT3;PRKCE;PRKCB;PRKCD;PRKCH;PRKCQ;PRKX;PRKG1","Kinase inhibitor"]
["PAXIP1","Prexasertib",0.16,0.445,-0.487,0.0558,-1.98,0.0476,0.0487,0.588,"0/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["RRP15","Pacritinib",0.0921,0.661,-0.554,0.026,-2.05,0.0406,0.0427,0.588,"0/-","FLT3, JAK2 inhibitor","FLT3;JAK2;TYK2","Kinase inhibitor"]
["RRM2B","CCT196969",-0.0379,0.857,0.59,0.0162,2.04,0.0409,0.0429,0.588,"0/+","pan-RAF, Src inhibitor","RAF1;BRAF;SRC;LCK","Kinase inhibitor"]
["RPL8","MST_312",-0.0957,0.649,0.55,0.0272,2.04,0.041,0.0431,0.588,"0/+","Telomerase inhibitor","TERT","Other"]
["CNDP2","Erastin",-0.428,0.033,0.234,0.382,1.99,0.0467,0.0489,0.589,"-/0","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["ISOC2","NVP_BGT226",-0.398,0.0486,0.281,0.292,2.03,0.0423,0.0433,0.589,"-/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CG;MTOR","Kinase inhibitor"]
["MARCHF5","Marimastat",-0.335,0.102,0.346,0.189,2.03,0.0426,0.0435,0.589,"0/0","MMP-9, MMP-1, MMP-2, MMP-14, MMP-7 inhibitor","MMP1;MMP2;MMP9;MMP7;MMP14","Other"]
["PGGHG","Agerafenib_CEP_32496",0.235,0.259,0.731,0.00129,1.98,0.0478,0.049,0.589,"0/+","BRAF(V600E) inhibitor","BRAF;RAF1;KIT;RET;LCK;ABL1;PDGFRB;CSF1R;MET;EGFR;KDR;EPHA2","Kinase inhibitor"]
["NGDN","Erastin",0.108,0.606,-0.525,0.0369,-1.98,0.048,0.0491,0.589,"0/-","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["RANGAP1","PF_03758309",0.272,0.188,-0.409,0.116,-2.04,0.0414,0.0435,0.589,"0/0","PAK4 inhibitor","PAK4","Kinase inhibitor"]
["CEPT1","Duvelisib",-0.407,0.0437,0.258,0.335,1.99,0.0468,0.0489,0.59,"-/0","PI3K inhibitor","PIK3CD","Kinase inhibitor"]
["CPT1A","Dactolisib",-0.439,0.028,0.22,0.414,1.99,0.047,0.0492,0.59,"-/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR;ATR;RPS6KB1","Kinase inhibitor"]
["MFSD8","8_amino_adenosine",-0.551,0.00429,0.0882,0.745,2.03,0.0428,0.0437,0.59,"-/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["LIPT1","Ralimetinib",0.00996,0.962,0.616,0.0111,2.02,0.043,0.0439,0.59,"0/+","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["LAMP2","Mercaptopurine",-0.562,0.00345,0.0709,0.794,2.02,0.0433,0.0441,0.59,"-/0","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["LIMK2","AZD1152_HQPA",-0.486,0.0137,0.174,0.52,2.02,0.0435,0.0443,0.59,"-/0","Aurora B inhibitor","AURKB","Kinase inhibitor"]
["PIKFYVE","Vandetanib",0.117,0.578,-0.518,0.0399,-1.97,0.0483,0.0495,0.59,"0/-","VEGFR, EGFR, RET inhibitor","KDR;FLT4;EGFR;RET","Kinase inhibitor"]
["PRDX5","SCH772984",-0.127,0.547,0.527,0.0361,2.04,0.0416,0.0437,0.59,"0/+","ERK1 and 2 inhibitor","MAPK3","Kinase inhibitor"]
["PRKRIP1","Entinostat",0.371,0.0679,-0.312,0.24,-2.04,0.0418,0.0439,0.59,"0/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["RALGAPA2","Sepantronium_bromide",0.0361,0.864,0.634,0.0084,2.03,0.042,0.0441,0.59,"0/+","Survivin inhibitor","BIRC5","Apoptotic modulator"]
["ROCK1","Sitravatinib",-0.143,0.494,0.513,0.0423,2.03,0.0422,0.0443,0.59,"0/+","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["EFHD2","Alisertib",-0.234,0.26,0.427,0.0994,1.98,0.0472,0.0495,0.591,"0/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["DKC1","Mocetinostat",-0.221,0.288,0.437,0.0907,1.98,0.0475,0.0497,0.591,"0/0","HDAC inhibitor (HDAC1 and 2-selective)","HDAC1;HDAC2;HDAC3;HDAC11","Differentiating.epigenetic modifier"]
["DDX3Y","Alpelisib",-0.134,0.522,0.506,0.0455,1.98,0.0477,0.0499,0.591,"0/+","PI3Kalpha selective inhibitor","PIK3CA","Kinase inhibitor"]
["MAPK9","Luminespib",-0.176,0.4,0.483,0.0579,2.02,0.0439,0.0447,0.591,"0/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["PCM1","SB743921",-0.0559,0.791,-0.633,0.00853,-1.97,0.0485,0.0498,0.591,"0/-","Mitotic inhibitor, Eg5, KSP inhibitor","KIF11","Kinesin inhibitor"]
["PFN2","Axitinib",0.152,0.468,-0.49,0.0541,-1.97,0.0488,0.0501,0.591,"0/0","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["PM20D2","JQ1",-0.364,0.074,0.299,0.261,1.97,0.0489,0.0502,0.591,"0/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["MTERF3","FRAX486",0.458,0.0215,-0.191,0.478,-1.97,0.0493,0.0505,0.591,"+/0","PAK1, 2, 3 inhibitor","PAK1","Kinase inhibitor"]
["PLEC","Raltitrexed",-0.14,0.504,0.497,0.05,1.96,0.0495,0.0507,0.591,"0/+","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["MTOR","Canertinib",0.289,0.161,-0.37,0.159,-1.96,0.0499,0.051,0.591,"0/0","Pan-HER inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["PPP6C","Prexasertib",-0.528,0.00663,0.122,0.654,2.03,0.0424,0.0444,0.591,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["RPF1","NVP_BGT226",0.356,0.0808,-0.325,0.22,-2.03,0.0427,0.0448,0.591,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CG;MTOR","Kinase inhibitor"]
["DHTKD1","Birinapant",-0.361,0.0764,0.304,0.252,1.98,0.0479,0.0501,0.592,"0/0","IAPs, SMAC mimetic","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["CDV3","BX_912",0.0056,0.979,-0.595,0.015,-1.98,0.0481,0.0503,0.592,"0/-","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["MINDY2","BX_912",0.288,0.163,-0.387,0.139,-2.01,0.0441,0.045,0.592,"0/0","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["ITGB1","KU_60019",-0.299,0.147,0.377,0.151,2.01,0.0442,0.0451,0.592,"0/0","ATM inhibitor","ATM","Kinase inhibitor"]
["RAD9A","Axitinib",-0.179,0.393,0.484,0.0575,2.03,0.0427,0.0448,0.592,"0/0","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["RTN4IP1","Sabutoclax",-0.159,0.447,0.498,0.0494,2.02,0.043,0.0451,0.592,"0/+","pan Bcl-2 family inhibitor","BCL2;BCL2L1;MCL1;BCL2A1","Apoptotic modulator"]
["CLASP1","GSK2656157",0.635,0.000645,0.0591,0.828,-1.98,0.0482,0.0504,0.593,"+/0","PERK inhibitor","EIF2AK3","Kinase inhibitor"]
["CYGB","Digoxin",-0.255,0.219,0.405,0.12,1.97,0.0484,0.0505,0.593,"0/0","Cardiac glycoside","ATP1A1;ITGB1;ITGB3;ITGA3;ITGA1","Other"]
["INTS11","NVP_BGT226",0.163,0.435,-0.491,0.0532,-2.01,0.0446,0.0454,0.593,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CG;MTOR","Kinase inhibitor"]
["MARK3","Sitravatinib",-0.518,0.00804,0.129,0.635,2.01,0.0447,0.0455,0.593,"-/0","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["METTL1","Cisplatin",0.216,0.299,-0.447,0.0822,-2.01,0.0449,0.0458,0.593,"0/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["IKZF5","Alpelisib",-0.351,0.0855,0.322,0.224,2,0.0453,0.0461,0.593,"0/0","PI3Kalpha selective inhibitor","PIK3CA","Kinase inhibitor"]
["MRC2","Bafetinib",0.0136,0.948,0.613,0.0116,2,0.0453,0.0462,0.593,"0/+","ABL, Lyn inhibitor","ABL1;LYN","Kinase inhibitor"]
["IPO13","EPZ015666",-0.382,0.0592,0.288,0.279,2,0.0456,0.0464,0.593,"0/0","PRMT5 inhibitor","PRMT5","Differentiating.epigenetic modifier"]
["PTPN18","Ibrutinib",-0.166,0.429,0.492,0.0529,2.02,0.0437,0.0457,0.593,"0/0","BTK inhibitor","BTK;BLK;EGFR;FYN;LYN;LCK;BRAF;WNK1","Kinase inhibitor"]
["PPM1M","Pomalidomide",0.0837,0.691,0.658,0.00559,2.02,0.0437,0.0458,0.593,"0/+","Immunomodulatory agent, anti-angiogenic","CRBN;PTGS2;TNF","Immunomodulatory"]
["CWC15","Gedatolisib",0.334,0.103,-0.329,0.213,-1.97,0.049,0.0511,0.594,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CG;MTOR","Kinase inhibitor"]
["MAP2K4","Ganetespib",-0.166,0.427,0.486,0.0563,2,0.0458,0.0466,0.594,"0/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["RAB7A","Nilotinib",-0.226,0.277,0.442,0.0867,2.01,0.0439,0.046,0.594,"0/0","ABL inhibitor","ABL1;KIT","Kinase inhibitor"]
["PRKCA","Cabazitaxel",0.167,0.424,-0.49,0.0542,-2.01,0.044,0.0461,0.594,"0/0","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["COQ3","AT9283",-0.51,0.00914,0.124,0.647,1.97,0.0492,0.0514,0.595,"-/0","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["DENND4B","OSU_03012",-0.453,0.0228,0.196,0.466,1.97,0.0493,0.0515,0.595,"-/0","PDPK1 inhibitor","PDPK1","Kinase inhibitor"]
["MAFF","AZD8055",-0.176,0.401,0.478,0.061,2,0.046,0.0468,0.595,"0/0","mTOR inhibitor","MTOR","Kinase inhibitor"]
["IRAK1","Erastin",-0.411,0.0413,0.255,0.341,1.99,0.0463,0.0471,0.595,"-/0","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["IGF2BP3","AR_42",-0.285,0.168,0.383,0.143,1.99,0.0464,0.0472,0.595,"0/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["PPP2CB","TGR_1202",-0.165,0.431,0.491,0.0535,2.01,0.0443,0.0464,0.595,"0/0","PI3Kdelta inhibitor","PIK3CD","Kinase inhibitor"]
["R3HDM2","Mitomycin_C",0.126,0.548,-0.52,0.039,-2.01,0.0446,0.0466,0.595,"0/-","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["PTGR1","OTS167",-0.116,0.581,0.527,0.036,2.01,0.0447,0.0467,0.595,"0/+","MELK inhibitor","MELK","Kinase inhibitor"]
["SEC11A","Megestrol_acetate",0.191,0.36,-0.468,0.0673,-2.01,0.045,0.047,0.595,"0/0","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["DHRS1","Prexasertib",-0.544,0.00498,0.0767,0.778,1.96,0.0499,0.052,0.596,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["DNAJC24","Amuvatinib",-0.229,0.271,0.424,0.102,1.96,0.0499,0.0521,0.596,"0/0","Broad TK inhibitor","KIT;PDGFRA;FLT3","Kinase inhibitor"]
["INTS12","Lonafarnib",-0.218,0.295,0.441,0.0873,1.99,0.0469,0.0477,0.596,"0/0","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["KRT1","Itraconazole",-0.431,0.0313,0.228,0.395,1.98,0.0473,0.048,0.596,"-/0","antifungal, hedgehog signaling inhibitor","CYP51A1;CYP3A4","Other"]
["PTPN2","PCI_34051",0.273,0.187,-0.398,0.127,-2,0.0451,0.0471,0.596,"0/0","HDAC8 inhibitor","HDAC8","Differentiating.epigenetic modifier"]
["RBL1","THZ2",0.351,0.0857,-0.323,0.223,-2,0.0452,0.0473,0.596,"0/0","CDK7 inhibitor","CDK7","Kinase inhibitor"]
["RFC5","Romidepsin",-0.177,0.398,0.479,0.0607,2,0.0455,0.0476,0.596,"0/0","HDAC inhibitor","HDAC1;HDAC2","Differentiating.epigenetic modifier"]
["JUNB","Taselisib",-0.435,0.0296,0.222,0.408,1.98,0.0477,0.0485,0.597,"-/0","PI3K alpha, delta, (gamma) selective inhibitor","PIK3CA;PIK3CD;PIK3CG","Kinase inhibitor"]
["RNF130","NVP_LCL161",-0.302,0.143,0.37,0.158,2,0.0455,0.0476,0.597,"0/0","IAPs, SMAC mimetic","XIAP;BIRC2","Apoptotic modulator"]
["SEC62","AZD7762",-0.463,0.0197,0.195,0.47,2,0.0457,0.0478,0.597,"-/0","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["RPL36AL","BI_2536",0.146,0.488,-0.502,0.0478,-2,0.046,0.0481,0.597,"0/-","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["SARS2","Abemaciclib",-0.109,0.605,-0.668,0.00471,-1.99,0.0462,0.0482,0.597,"0/-","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["MROH1","GSK650394",-0.21,0.313,0.445,0.0843,1.98,0.048,0.0488,0.598,"0/0","SGK1 and 2 inhibitor","SGK1","Kinase inhibitor"]
["MIS12","BMS_911543",-0.355,0.082,0.31,0.243,1.98,0.0482,0.0489,0.598,"0/0","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["MCM10","Bleomycin",0.28,0.176,-0.383,0.144,-1.97,0.0485,0.0492,0.598,"0/0","Glycopeptide antibiotic, causes DNA breaks","DNA","Conv.Chemo"]
["S100A13","GSK2256098",-0.398,0.049,0.269,0.314,1.99,0.0465,0.0486,0.598,"-/0","FAK inhibitor","PTK2","Kinase inhibitor"]
["KIF2A","Romidepsin",0.0653,0.756,0.638,0.00781,1.97,0.0487,0.0493,0.599,"0/+","HDAC inhibitor","HDAC1;HDAC2","Differentiating.epigenetic modifier"]
["IMMP1L","Glesatinib",0.133,0.525,-0.505,0.0463,-1.97,0.0487,0.0494,0.599,"0/-","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["SAAL1","Aldoxorubicin",0.0343,0.871,-0.579,0.0188,-1.99,0.0469,0.0489,0.599,"0/-","Topoisomerase II inhibitor, Albumin binding","TOP2A;TOP2B","Conv.Chemo"]
["RAD54B","Ivosidenib",0.0392,0.852,-0.575,0.0198,-1.98,0.0472,0.0492,0.599,"0/-","IDH1 R132H and R132C inhibitor","IDH1","Differentiating.epigenetic modifier"]
["PPP3R1","Deferoxamine",-0.277,0.18,0.388,0.137,1.98,0.0472,0.0492,0.599,"0/0","Iron chelator","APP","Other"]
["MCM2","8_chloro_adenosine",0.0751,0.721,-0.546,0.0287,-1.97,0.0493,0.0499,0.6,"0/-","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["MIEF1","GDC_0084",0.181,0.386,-0.465,0.0695,-1.96,0.0496,0.0502,0.6,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["RBMX2","Selinexor",-6.43E-3,0.976,-0.604,0.0132,-1.98,0.0475,0.0495,0.6,"0/-","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["RSBN1L","Midostaurin",0.145,0.49,-0.498,0.0497,-1.98,0.0478,0.0498,0.6,"0/-","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["METTL17","Triapine",-0.476,0.0161,0.167,0.537,1.96,0.0497,0.0504,0.601,"-/0","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["MNT","Alisertib",0.211,0.312,-0.44,0.088,-1.96,0.0498,0.0505,0.601,"0/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["RPL9","ML390",0.372,0.0674,0.794,2.42E-4,1.98,0.0482,0.0502,0.601,"0/+","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["RANGAP1","Ganetespib",0.479,0.0154,-0.167,0.537,-1.97,0.0485,0.0505,0.601,"+/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["RUFY3","Mitoxantrone",0.365,0.0732,-0.298,0.262,-1.97,0.0486,0.0506,0.601,"0/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["PPM1G","A_1210477",-0.205,0.325,0.447,0.0826,1.97,0.0489,0.0509,0.601,"0/0","MCL-1 inhibitor","MCL1","Apoptotic modulator"]
["PTPN2","E7820",0.391,0.0535,-0.269,0.313,-1.97,0.049,0.051,0.602,"0/0","Integrin alpha2 expression inhibitor","ITGA2","Other"]
["PSMA7","Digoxin",0.025,0.906,-0.581,0.0183,-1.97,0.049,0.051,0.602,"0/-","Cardiac glycoside","ATP1A1;ITGB1;ITGB3;ITGA3;ITGA1","Other"]
["SDF2","LY_2584702",-0.583,0.00221,0.0212,0.938,1.97,0.049,0.051,0.602,"-/0","p70S6K inhibitor","RPS6KB1","Kinase inhibitor"]
["RPL4","Bortezomib",-0.0468,0.824,-0.626,0.00942,-1.97,0.049,0.051,0.602,"0/-","Proteasome inhibitor (26S subunit)","PSMB5;PSMB1","Protease.proteasome inhibitor"]
["RNASET2","AZD1775",-0.378,0.0627,0.283,0.287,1.97,0.049,0.051,0.602,"0/0","Wee1 inhibitor","WEE1","Kinase inhibitor"]
["RHOT2","Temsirolimus",0.0157,0.941,0.607,0.0126,1.97,0.049,0.051,0.602,"0/+","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["PPP1CB","Flutamide",0.193,0.356,-0.457,0.0752,-1.97,0.049,0.051,0.602,"0/0","Nonsteroidal antiandrogen","AR;AHR;NR1I2","Hormone therapy"]
["PTGER4","PF_670462",-0.179,0.391,0.468,0.0676,1.97,0.049,0.051,0.602,"0/0","CK1epsilon and CK1delta inhibitor","CSNK1D;CSNK1E","Kinase inhibitor"]
["PPP6R1","Triapine",-0.329,0.108,0.334,0.206,1.97,0.049,0.051,0.602,"0/0","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["RELA","Litronesib",-0.143,0.495,0.496,0.0505,1.97,0.049,0.051,0.602,"0/0","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["RBBP5","Capmatinib",0.484,0.0142,-0.159,0.556,-1.97,0.049,0.051,0.602,"+/0","MET inhibitor","MET","Kinase inhibitor"]
["PRKD3","Mercaptopurine",-0.252,0.223,0.406,0.119,1.97,0.049,0.051,0.602,"0/0","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["RRP9","Flutamide",-0.209,0.316,0.443,0.0853,1.97,0.049,0.051,0.602,"0/0","Nonsteroidal antiandrogen","AR;AHR;NR1I2","Hormone therapy"]
["PTGER4","VER_155008",-0.29,0.16,0.371,0.157,1.97,0.049,0.051,0.602,"0/0","HSP70 inhibitor","HSPA1A;HSPA1B;HSPA8;HSPA5","HSP inhibitor"]
["RAB5C","Imiquimod",-0.00649,0.975,-0.601,0.0138,-1.97,0.049,0.051,0.602,"0/-","Immunomodulatory agent, TLR7 agonist","TLR7;TLR8","Immunomodulatory"]
["SCOC","Fludarabine",-0.158,0.452,0.485,0.0568,1.97,0.049,0.051,0.602,"0/0","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["SAMD9L","Raltitrexed",-0.332,0.105,0.331,0.211,1.97,0.049,0.051,0.602,"0/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["SART1","Eltanexor",0.163,0.437,-0.481,0.0592,-1.97,0.049,0.051,0.602,"0/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["PPP4R3A","Sabutoclax",-0.273,0.186,0.387,0.139,1.97,0.049,0.051,0.602,"0/0","pan Bcl-2 family inhibitor","BCL2;BCL2L1;MCL1;BCL2A1","Apoptotic modulator"]
["PSMC3IP","Ridaforolimus",0.235,0.258,-0.421,0.104,-1.97,0.049,0.0511,0.602,"0/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["SCPEP1","Omipalisib",-0.42,0.0367,0.237,0.378,1.97,0.049,0.0511,0.602,"-/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["RPL30","Topotecan",0.453,0.0228,-0.197,0.465,-1.97,0.049,0.0511,0.602,"+/0","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["RAB11B","Paclitaxel",-0.322,0.117,0.341,0.196,1.97,0.049,0.0511,0.602,"0/0","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["PPAT","NVP_LCL161",0.0474,0.822,-0.566,0.0224,-1.97,0.049,0.0511,0.602,"0/-","IAPs, SMAC mimetic","XIAP;BIRC2","Apoptotic modulator"]
["SEC16A","Alpelisib",-0.0787,0.709,0.544,0.0294,1.97,0.049,0.0511,0.602,"0/+","PI3Kalpha selective inhibitor","PIK3CA","Kinase inhibitor"]
["RB1CC1","MST_312",0.112,0.594,-0.52,0.039,-1.97,0.049,0.0511,0.602,"0/-","Telomerase inhibitor","TERT","Other"]
["RRAGB","Alisertib",-0.712,{"v":6.55e-05,"d":"6.55E-05"},-0.2,0.458,1.97,0.049,0.0511,0.602,"-/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["PPRC1","Tubastatin_A",0.219,0.293,-0.435,0.0922,-1.97,0.049,0.0511,0.602,"0/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["POTEF","Oprozomib",0.033,0.876,0.618,0.0108,1.97,0.049,0.0511,0.602,"0/+","proteasome (20 S) inhibitor","PSMB5;PSMB8","Protease.proteasome inhibitor"]
["PRKCQ","JQ1",0.205,0.325,-0.447,0.0829,-1.97,0.049,0.0511,0.602,"0/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["RPP30","Carfilzomib",-0.148,0.48,-0.685,0.00344,-1.97,0.049,0.0511,0.602,"0/-","Proteasome inhibitor (20S subunit)","PSMB5;PSMB8;PSMB1;PSMB2;PSMB9;PSMB10","Protease.proteasome inhibitor"]
["RRP1","Mubritinib",0.189,0.365,0.706,0.00222,1.97,0.049,0.0511,0.602,"0/+","HER2 inhibitor","ERBB2","Kinase inhibitor"]
["SEC13","AZD1208",-0.36,0.0774,0.302,0.255,1.97,0.049,0.0511,0.602,"0/0","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["POLR3K","ML390",0.137,0.514,-0.501,0.048,-1.97,0.049,0.0511,0.602,"0/-","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["RBFA","Omipalisib",-0.344,0.0924,0.319,0.229,1.97,0.049,0.0511,0.602,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["PTPN4","Brigatinib",-0.377,0.0629,0.283,0.287,1.97,0.0491,0.0511,0.602,"0/0","ALK inhibitor, including gatekeeper mutant ALK","ALK;ROS1;IGF1R;EGFR;INSR;ABL1;FLT3;MET;ERBB2;ERBB4","Kinase inhibitor"]
["RBM3","AR_42",0.0278,0.895,-0.579,0.0188,-1.97,0.0491,0.0511,0.602,"0/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC8","Differentiating.epigenetic modifier"]
["RPS27L","Pevonedistat",0.0927,0.66,0.654,0.00604,1.97,0.0491,0.0511,0.602,"0/+","NAE inhibitor","NAE1","Metabolic modifier"]
["RMND1","Sorafenib",0.352,0.084,-0.31,0.243,-1.97,0.0491,0.0511,0.602,"0/0","BRAF, FGFR-1, VEGFR-2 and -3, PDGFR-beta, KIT, and FLT3 inhibitor","BRAF;FGFR1;KDR;FLT3;KIT;FLT4;PDGFRB","Kinase inhibitor"]
["PTPRK","Verdinexor",-0.407,0.0435,0.251,0.348,1.97,0.0491,0.0511,0.602,"-/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["PPP2R3C","Sepantronium_bromide",0.207,0.322,-0.445,0.0839,-1.97,0.0491,0.0511,0.602,"0/0","Survivin inhibitor","BIRC5","Apoptotic modulator"]
["PPIL1","Lifirafenib_BGB_283",-0.14,0.505,0.499,0.0492,1.97,0.0491,0.0511,0.602,"0/+","Raf inhibitor","RAF1;BRAF;EGFR","Kinase inhibitor"]
["RMND1","CCT196969",0.141,0.501,0.681,0.00369,1.97,0.0491,0.0511,0.602,"0/+","pan-RAF, Src inhibitor","RAF1;BRAF;SRC;LCK","Kinase inhibitor"]
["PYCR1","Indibulin",0.547,0.00468,-0.0746,0.784,-1.97,0.0491,0.0511,0.602,"+/0","Mitoric inhibitor, Microtubule depolymerizer","TUBB","Conv.Chemo"]
["RPS7","Alpelisib",0.142,0.499,-0.497,0.05,-1.97,0.0491,0.0511,0.602,"0/-","PI3Kalpha selective inhibitor","PIK3CA","Kinase inhibitor"]
["PPP1R13B","Ixazomib",-0.351,0.0851,0.311,0.241,1.97,0.0491,0.0511,0.602,"0/0","20S proteasome inhibitor","PSMB5","Protease.proteasome inhibitor"]
["PPID","AZD1775",0.634,6.6E-4,0.0601,0.825,-1.97,0.0491,0.0511,0.602,"+/0","Wee1 inhibitor","WEE1","Kinase inhibitor"]
["RETREG2","Lonafarnib",0.0782,0.71,-0.544,0.0293,-1.97,0.0491,0.0511,0.602,"0/-","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["SAFB2","Cabazitaxel",0.263,0.204,-0.396,0.129,-1.97,0.0491,0.0511,0.602,"0/0","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["SDAD1","Pemetrexed",0.56,3.64E-3,-0.0563,0.836,-1.97,0.0491,0.0511,0.602,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["SCAMP2","Spebrutinib",-0.0512,0.808,0.563,0.0232,1.97,0.0491,0.0511,0.602,"0/+","BTK inhibitor","BTK","Kinase inhibitor"]
["RPL10A","PIM_447",0.208,0.318,-0.444,0.0848,-1.97,0.0491,0.0511,0.602,"0/0","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["RCL1","Pemetrexed",0.567,3.13E-3,-0.0454,0.867,-1.97,0.0491,0.0511,0.602,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["RPS5","S_63845",-0.198,0.342,0.452,0.0786,1.97,0.0491,0.0511,0.602,"0/0","MCL-1 inhibitor","MCL1","Apoptotic modulator"]
["SCNM1","Danusertib",0.427,0.0331,-0.228,0.396,-1.97,0.0491,0.0511,0.602,"+/0","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["RBM25","AT9283",-0.43,0.0321,0.225,0.402,1.97,0.0491,0.0511,0.602,"-/0","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["RUFY3","ARV_825",0.429,0.0325,-0.226,0.4,-1.97,0.0491,0.0511,0.602,"+/0","BET-targeting PROTAC","BRD4","Differentiating.epigenetic modifier"]
["RICTOR","GDC_0084",-0.304,0.139,0.357,0.174,1.97,0.0491,0.0511,0.602,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["SAFB2","Amuvatinib",0.417,0.0382,-0.24,0.371,-1.97,0.0491,0.0511,0.602,"+/0","Broad TK inhibitor","KIT;PDGFRA;FLT3","Kinase inhibitor"]
["RAB3IP","Encorafenib",-0.0929,0.659,0.534,0.0333,1.97,0.0491,0.0511,0.602,"0/+","BRAF(V600E) inhibitor","BRAF;RAF1","Kinase inhibitor"]
["RILPL1","Ganetespib",-0.397,0.0496,0.262,0.326,1.97,0.0491,0.0511,0.602,"-/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["RABGAP1L","GSK923295",0.391,0.0534,-0.269,0.314,-1.97,0.0491,0.0511,0.602,"0/0","CENP-E inhibitor","CENPE","Kinesin inhibitor"]
["PTPRC","Sonidegib",0.0262,0.901,-0.58,0.0186,-1.97,0.0491,0.0511,0.602,"0/-","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["RPS28","AZD_6482",0.219,0.292,-0.435,0.0926,-1.97,0.0491,0.0511,0.602,"0/0","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["RBM14","Ravoxertinib",0.375,0.065,-0.286,0.283,-1.97,0.0491,0.0511,0.602,"0/0","ERK inhibitor","MAPK3","Kinase inhibitor"]
["RERE","Crenolanib",-0.446,0.0255,0.206,0.444,1.97,0.0491,0.0511,0.602,"-/0","PDGFRA and PDGFRB inhibitor","PDGFRA","Kinase inhibitor"]
["RGS3","Bosutinib",-0.446,0.0253,0.205,0.446,1.97,0.0491,0.0511,0.602,"-/0","ABL, Src inhibitor","ABL1;LYN;HCK;SRC;EPHB2;NTRK1;NTRK2;TXK","Kinase inhibitor"]
["RCAN3","Prexasertib",-0.232,0.265,0.424,0.102,1.97,0.0491,0.0511,0.602,"0/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["RPL15","Marimastat",-0.0334,0.874,0.575,0.0198,1.97,0.0491,0.0511,0.602,"0/+","MMP-9, MMP-1, MMP-2, MMP-14, MMP-7 inhibitor","MMP1;MMP2;MMP9;MMP7;MMP14","Other"]
["RPUSD2","Buparlisib",0.18,0.39,0.701,2.47E-3,1.97,0.0491,0.0511,0.602,"0/+","PI3K inhibitor, pan-class I","PIK3CA;PIK3CB;PIK3CG;PIK3CD;MTOR;PIK3C3","Kinase inhibitor"]
["SELENOS","BX_912",0.209,0.317,-0.443,0.0854,-1.97,0.0491,0.0511,0.602,"0/0","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["RBM14","Talazoparib",0.297,0.149,-0.364,0.165,-1.97,0.0491,0.0512,0.602,"0/0","PARP1 and 2 inhibitor","PARP1;PARP2","Differentiating.epigenetic modifier"]
["RPL6","BI_2536",0.261,0.207,-0.398,0.127,-1.97,0.0491,0.0512,0.602,"0/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["POLR3D","Birabresib",0.254,0.221,-0.404,0.12,-1.97,0.0491,0.0512,0.602,"0/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["RBM14","Prexasertib",0.419,0.0372,-0.237,0.376,-1.97,0.0491,0.0512,0.602,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["SDHC","PS_1145",-0.0816,0.698,0.542,0.0302,1.97,0.0491,0.0512,0.602,"0/+","IKK-2 inhibitor","IKBKB","Kinase inhibitor"]
["REPIN1","AZD_6482",-0.323,0.115,0.339,0.199,1.97,0.0491,0.0512,0.602,"0/0","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["S1PR4","Tivozanib",-0.163,0.437,0.481,0.0594,1.97,0.0491,0.0512,0.602,"0/0","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["RNASEH2A","Paclitaxel",0.0518,0.806,-0.562,0.0233,-1.97,0.0491,0.0512,0.602,"0/-","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["RASA1","Triapine",-0.305,0.138,0.357,0.175,1.97,0.0491,0.0512,0.602,"0/0","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["RCC1","BX_912",0.196,0.347,-0.454,0.0776,-1.97,0.0491,0.0512,0.602,"0/0","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["RNF25","Triciribine",0.0738,0.726,-0.547,0.0283,-1.97,0.0491,0.0512,0.602,"0/-","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["POLRMT","Ixazomib",0.345,0.0912,-0.317,0.231,-1.97,0.0492,0.0512,0.602,"0/0","20S proteasome inhibitor","PSMB5","Protease.proteasome inhibitor"]
["SART1","Valrubicin",0.307,0.135,-0.354,0.178,-1.97,0.0492,0.0512,0.602,"0/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["RFTN1","Amuvatinib",0.139,0.508,-0.499,0.0489,-1.97,0.0492,0.0512,0.602,"0/-","Broad TK inhibitor","KIT;PDGFRA;FLT3","Kinase inhibitor"]
["RING1","ABT_751",-0.546,0.00471,0.0747,0.783,1.97,0.0492,0.0512,0.602,"-/0","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["PSMD9","Tucidinostat",-0.273,0.186,0.387,0.139,1.97,0.0492,0.0512,0.602,"0/0","HDAC1, 2, 3 and 10 inhibitor","HDAC1;HDAC2;HDAC3;HDAC10","Differentiating.epigenetic modifier"]
["PSMD5","Floxuridine",-0.436,0.0295,0.218,0.418,1.97,0.0492,0.0512,0.602,"-/0","Antimetabolite, Analog of 5-fluorouracil","TYMS","Conv.Chemo"]
["RPS10","Altiratinib",0.295,0.152,-0.366,0.163,-1.97,0.0492,0.0512,0.602,"0/0","MET, Tie-2 inhibitor","MET;NTRK1;NTRK3;NTRK2;TEK;FLT3;KIT;KDR","Kinase inhibitor"]
["RACGAP1","Paclitaxel",0.313,0.128,-0.349,0.185,-1.97,0.0492,0.0512,0.602,"0/0","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["RPL32","Nelarabine",0.214,0.303,-0.438,0.0894,-1.97,0.0492,0.0512,0.602,"0/0","Antimetabolite, Nucleoside analog, DNA, RNA synth inhibitor","DNA","Conv.Chemo"]
["RAC3","Cytarabine.Idarubicin",0.368,0.0706,-0.294,0.27,-1.97,0.0492,0.0512,0.602,"0/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["RNF8","Vinorelbine",0.433,0.0306,-0.221,0.411,-1.97,0.0492,0.0512,0.602,"+/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["PROSER3","Duvelisib",0.0515,0.807,-0.563,0.0233,-1.97,0.0492,0.0512,0.602,"0/-","PI3K inhibitor","PIK3CD","Kinase inhibitor"]
["PPM1B","PIM_447",-0.402,0.0462,0.256,0.339,1.97,0.0492,0.0512,0.602,"-/0","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["PTGFRN","AMG319",0.397,0.0492,-0.262,0.328,-1.97,0.0492,0.0512,0.602,"+/0","PI3K delta inhibitor","PIK3CD","Kinase inhibitor"]
["RAB40C","UNC0638",-0.366,0.072,0.295,0.267,1.97,0.0492,0.0512,0.602,"0/0","G9a, GLP inhibitor","EHMT2","Differentiating.epigenetic modifier"]
["PPP1CC","Marimastat",-0.0556,0.792,0.56,0.0241,1.97,0.0492,0.0512,0.602,"0/+","MMP-9, MMP-1, MMP-2, MMP-14, MMP-7 inhibitor","MMP1;MMP2;MMP9;MMP7;MMP14","Other"]
["SAP130","PF_04708671",0.0321,0.879,-0.576,0.0196,-1.97,0.0492,0.0512,0.602,"0/-","p70S6K inhibitor","RPS6KB1","Kinase inhibitor"]
["SECISBP2","Daporinad",0.595,1.72E-3,-0.00334,0.99,-1.97,0.0492,0.0512,0.602,"+/0","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["RUFY2","Acitretin",-0.192,0.358,0.457,0.075,1.97,0.0492,0.0512,0.602,"0/0","Retinoic acid receptor agonist","RARA;RARB;RXRA;RXRB;RXRG","Differentiating.epigenetic modifier"]
["RING1","Glesatinib",-0.396,0.0498,0.263,0.326,1.97,0.0492,0.0512,0.602,"-/0","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["PPP1R9B","Mercaptopurine",-0.218,0.295,0.435,0.0918,1.97,0.0492,0.0512,0.602,"0/0","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["RPS27L","Epirubicin",0.0454,0.829,0.625,0.0096,1.97,0.0492,0.0512,0.602,"0/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["S100A10","PS_1145",0.0182,0.931,0.608,0.0124,1.97,0.0492,0.0512,0.602,"0/+","IKK-2 inhibitor","IKBKB","Kinase inhibitor"]
["REL","THZ2",-0.178,0.395,0.469,0.0671,1.97,0.0492,0.0512,0.602,"0/0","CDK7 inhibitor","CDK7","Kinase inhibitor"]
["RPL15","GSK_2334470",0.122,0.563,-0.512,0.0425,-1.97,0.0492,0.0512,0.602,"0/-","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["RFC5","Etoposide",0.146,0.486,-0.494,0.0519,-1.97,0.0492,0.0512,0.602,"0/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["QSOX1","Erastin",-0.275,0.184,0.385,0.141,1.97,0.0492,0.0512,0.602,"0/0","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["PTK2","Palomid_529",-0.105,0.617,0.525,0.0369,1.97,0.0492,0.0512,0.602,"0/+","AKT, MTOR, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3;MTOR","Kinase inhibitor"]
["SDHC","Methotrexate",-0.465,0.0191,0.182,0.5,1.97,0.0492,0.0512,0.602,"-/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["RPS18","Exemestane",0.183,0.38,-0.464,0.0702,-1.97,0.0492,0.0512,0.602,"0/0","Aromatase inhibitor","CYP19A1","Hormone therapy"]
["RARA","PD0325901",-0.384,0.0579,0.276,0.301,1.97,0.0492,0.0512,0.602,"0/0","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["RAD51C","GSK650394",0.337,0.0991,-0.325,0.22,-1.97,0.0492,0.0512,0.602,"0/0","SGK1 and 2 inhibitor","SGK1","Kinase inhibitor"]
["PPP1R10","Birinapant",0.349,0.0874,-0.313,0.238,-1.97,0.0492,0.0512,0.602,"0/0","IAPs, SMAC mimetic","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["RARS2","Sunitinib",0.663,3.01E-4,0.11,0.684,-1.97,0.0492,0.0512,0.602,"+/0","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["QSER1","8_amino_adenosine",0.297,0.15,-0.365,0.165,-1.97,0.0492,0.0512,0.602,"0/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["SECISBP2","Ponatinib",0.117,0.579,-0.516,0.0407,-1.97,0.0492,0.0512,0.602,"0/-","Broad TK inhibitor","ABL1;PDGFRA;KDR;FGFR1;SRC;KIT","Kinase inhibitor"]
["PPM1L","Pemetrexed",0.147,0.483,-0.493,0.0523,-1.97,0.0492,0.0512,0.602,"0/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["PSMG4","Mitoxantrone",-0.0245,0.907,-0.612,0.0117,-1.97,0.0492,0.0513,0.602,"0/-","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["RPN1","Acitretin",-0.301,0.144,0.361,0.17,1.97,0.0492,0.0513,0.602,"0/0","Retinoic acid receptor agonist","RARA;RARB;RXRA;RXRB;RXRG","Differentiating.epigenetic modifier"]
["RFC5","Ridaforolimus",0.118,0.573,-0.515,0.0413,-1.97,0.0492,0.0513,0.602,"0/-","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["RSPRY1","Sorafenib",-0.225,0.278,0.429,0.0974,1.97,0.0492,0.0513,0.602,"0/0","BRAF, FGFR-1, VEGFR-2 and -3, PDGFR-beta, KIT, and FLT3 inhibitor","BRAF;FGFR1;KDR;FLT3;KIT;FLT4;PDGFRB","Kinase inhibitor"]
["PRDM11","Lifirafenib_BGB_283",-0.362,0.0755,0.3,0.26,1.97,0.0492,0.0513,0.602,"0/0","Raf inhibitor","RAF1;BRAF;EGFR","Kinase inhibitor"]
["RABGAP1","UNC0638",0.444,0.0262,-0.208,0.44,-1.97,0.0492,0.0513,0.602,"+/0","G9a, GLP inhibitor","EHMT2","Differentiating.epigenetic modifier"]
["RPL23","Raltitrexed",0.66,0.000334,0.104,0.702,-1.97,0.0492,0.0513,0.602,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["RETREG2","Midostaurin",-0.35,0.0866,0.312,0.239,1.97,0.0492,0.0513,0.602,"0/0","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["SACS","LY_2874455",0.399,0.0483,-0.26,0.332,-1.97,0.0492,0.0513,0.602,"+/0","FGFR inhibitor","FGFR1;FGFR2;FGFR3","Kinase inhibitor"]
["SCAF11","MK_8745",0.3,0.145,-0.361,0.169,-1.97,0.0492,0.0513,0.602,"0/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["PPP1CA","Carfilzomib",-0.119,0.57,0.514,0.0417,1.97,0.0492,0.0513,0.602,"0/+","Proteasome inhibitor (20S subunit)","PSMB5;PSMB8;PSMB1;PSMB2;PSMB9;PSMB10","Protease.proteasome inhibitor"]
["RNF187","Tivozanib",0.155,0.459,-0.487,0.056,-1.97,0.0492,0.0513,0.602,"0/0","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["PRKACB","Tasquinimod",-0.214,0.305,0.439,0.0891,1.97,0.0492,0.0513,0.602,"0/0","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["PTGS1","Topotecan",-0.341,0.0953,0.321,0.226,1.97,0.0492,0.0513,0.602,"0/0","Topoisomerase I inhibitor, Camptothecin analog","TOP1","Conv.Chemo"]
["PTPRCAP","CC_115",0.513,0.0088,-0.121,0.655,-1.97,0.0492,0.0513,0.602,"+/0","mTOR, DNA-PK inhibitor","MTOR;PIK3CA;PRKDC","Kinase inhibitor"]
["PTK2B","Erastin",-0.048,0.82,0.565,0.0226,1.97,0.0492,0.0513,0.602,"0/+","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["RBBP9","AZD1152_HQPA",-0.455,0.0223,0.195,0.47,1.97,0.0492,0.0513,0.602,"-/0","Aurora B inhibitor","AURKB","Kinase inhibitor"]
["PSMD12","Entinostat",3.8E-3,0.986,-0.594,0.0152,-1.97,0.0492,0.0513,0.602,"0/-","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["SAMHD1","Masitinib",-0.282,0.171,0.378,0.149,1.97,0.0493,0.0513,0.602,"0/0","KIT inhibitor","KIT","Kinase inhibitor"]
["SELENOF","Doramapimod",-0.323,0.115,0.339,0.199,1.97,0.0493,0.0513,0.602,"0/0","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["RNASEH2C","Mitomycin_C",-0.00818,0.969,0.591,0.0158,1.97,0.0493,0.0513,0.602,"0/+","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["REEP5","Cerdulatinib",-0.055,0.794,0.56,0.0241,1.97,0.0493,0.0513,0.602,"0/+","JAK, SYK inhibitor","JAK1;JAK2;JAK3;TYK2;SYK","Kinase inhibitor"]
["RPF2","PCI_34051",0.107,0.609,-0.523,0.0378,-1.97,0.0493,0.0513,0.602,"0/-","HDAC8 inhibitor","HDAC8","Differentiating.epigenetic modifier"]
["PPM1E","Epirubicin",0.452,0.0234,-0.198,0.462,-1.97,0.0493,0.0513,0.602,"+/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["RAP1B","Ivosidenib",0.0378,0.858,0.62,0.0103,1.97,0.0493,0.0513,0.602,"0/+","IDH1 R132H and R132C inhibitor","IDH1","Differentiating.epigenetic modifier"]
["RAB28","Rociletinib",0.132,0.529,-0.504,0.0464,-1.97,0.0493,0.0513,0.602,"0/-","EGFR(L858R, T790M) inhibitor","EGFR","Kinase inhibitor"]
["RAPGEF6","Fluorouracil",-0.16,0.445,0.483,0.0583,1.97,0.0493,0.0513,0.602,"0/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","TYMS","Conv.Chemo"]
["PSD3","Deferoxamine",-0.325,0.113,0.337,0.201,1.97,0.0493,0.0513,0.602,"0/0","Iron chelator","APP","Other"]
["RIF1","Etoposide",0.422,0.0355,-0.233,0.385,-1.97,0.0493,0.0513,0.602,"+/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["PRPSAP1","FRAX486",-0.209,0.316,0.443,0.086,1.97,0.0493,0.0513,0.602,"0/0","PAK1, 2, 3 inhibitor","PAK1","Kinase inhibitor"]
["POLR1E","BMS_911543",0.455,0.0222,-0.194,0.471,-1.97,0.0493,0.0513,0.602,"+/0","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["RRM2B","Silmitasertib",-0.0144,0.946,0.587,0.0168,1.97,0.0493,0.0513,0.602,"0/+","CSNK2A1 inhibitor","CSNK2A1","Kinase inhibitor"]
["SCOC","Belinostat",-0.188,0.367,-0.706,0.00226,-1.97,0.0493,0.0513,0.602,"0/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["RPS11","Altiratinib",0.363,0.0749,-0.299,0.261,-1.97,0.0493,0.0513,0.602,"0/0","MET, Tie-2 inhibitor","MET;NTRK1;NTRK3;NTRK2;TEK;FLT3;KIT;KDR","Kinase inhibitor"]
["RPS6KA4","Resminostat",-0.534,0.00595,0.0916,0.736,1.97,0.0493,0.0513,0.602,"-/0","HDAC1, 3, 6 inhibitor","HDAC1;HDAC3;HDAC6","Differentiating.epigenetic modifier"]
["RRP12","GSK650394",0.387,0.056,-0.272,0.307,-1.97,0.0493,0.0513,0.602,"0/0","SGK1 and 2 inhibitor","SGK1","Kinase inhibitor"]
["PPP2R5E","Gandotinib",-0.102,0.627,0.527,0.0361,1.97,0.0493,0.0513,0.602,"0/+","JAK2 inhibitor","JAK2;JAK1;FLT3;FLT4;FGFR2;TYK2;NTRK2;FGFR3;KDR;ALK","Kinase inhibitor"]
["SDF2","A_419259",0.296,0.151,-0.365,0.164,-1.97,0.0493,0.0513,0.602,"0/0","HCK and other SRC family kinase inhibitor","SRC;LCK;LYN;HCK","Kinase inhibitor"]
["RSL24D1","BX_912",0.398,0.0488,-0.26,0.33,-1.97,0.0493,0.0513,0.602,"+/0","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["RDH11","C646",-0.209,0.317,0.443,0.0858,1.97,0.0493,0.0513,0.602,"0/0","EP300, CREB-binding protein (CBP) inhibitor","EP300","Differentiating.epigenetic modifier"]
["RPE","Tucidinostat",-0.28,0.175,0.38,0.146,1.97,0.0493,0.0513,0.602,"0/0","HDAC1, 2, 3 and 10 inhibitor","HDAC1;HDAC2;HDAC3;HDAC10","Differentiating.epigenetic modifier"]
["RWDD3","Taselisib",0.299,0.147,-0.362,0.168,-1.97,0.0493,0.0513,0.602,"0/0","PI3K alpha, delta, (gamma) selective inhibitor","PIK3CA;PIK3CD;PIK3CG","Kinase inhibitor"]
["RPS29","Vactosertib_TEW_7197",-0.193,0.356,0.456,0.0756,1.97,0.0493,0.0513,0.602,"0/0","TGF receptor ALK4, ALK5 inhibitor","TGFBR1;ACVR1B","Kinase inhibitor"]
["SDE2","Palbociclib",0.366,0.0719,-0.295,0.268,-1.97,0.0493,0.0513,0.602,"0/0","Topoisomerase I inhibitor, Camptothecin analog","CDK4;CDK6","Kinase inhibitor"]
["S100A1","Encorafenib",-0.474,0.0166,0.17,0.528,1.97,0.0493,0.0513,0.602,"-/0","BRAF(V600E) inhibitor","BRAF;RAF1","Kinase inhibitor"]
["SEC11A","BMS863233",-0.478,0.0156,0.165,0.541,1.97,0.0493,0.0513,0.602,"-/0","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["RUNX2","Fostamatinib",0.481,0.0149,-0.162,0.549,-1.97,0.0493,0.0513,0.602,"+/0","SYK inhibitor","SYK","Kinase inhibitor"]
["RNF41","CC_223",-0.557,3.81E-3,0.0589,0.828,1.97,0.0493,0.0513,0.602,"-/0","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["POLR2D","AZD_5363",0.0731,0.729,-0.547,0.0282,-1.97,0.0493,0.0513,0.602,"0/-","AKT inhibitor","AKT1;AKT2;AKT3;ROCK2","Kinase inhibitor"]
["RTTN","Megestrol_acetate",0.305,0.138,-0.356,0.176,-1.97,0.0493,0.0513,0.602,"0/0","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["PPP6C","Onalespib",-0.131,0.534,0.505,0.0459,1.97,0.0493,0.0513,0.602,"0/+","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["PSMD7","Tubastatin_A",0.296,0.15,-0.365,0.165,-1.97,0.0493,0.0513,0.602,"0/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["RANBP3","AZD_5363",0.0933,0.657,-0.533,0.0336,-1.97,0.0493,0.0513,0.602,"0/-","AKT inhibitor","AKT1;AKT2;AKT3;ROCK2","Kinase inhibitor"]
["RELCH","GSK269962",-0.423,0.0351,0.232,0.387,1.97,0.0493,0.0513,0.602,"-/0","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["PRMT9","Tosedostat",-0.576,0.00261,0.0318,0.907,1.97,0.0493,0.0513,0.602,"-/0","Aminopeptidase inhibitor","ANPEP","Protease.proteasome inhibitor"]
["PRDX3","Glasdegib",-0.17,0.416,0.474,0.0634,1.97,0.0493,0.0514,0.602,"0/0","Smo inhibitor","SMO","Hedgehog inhibitor"]
["PPIA","ML390",-1.57E-3,0.994,-0.597,0.0145,-1.97,0.0493,0.0514,0.602,"0/-","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["SDSL","Glasdegib",-0.294,0.154,0.367,0.162,1.97,0.0494,0.0514,0.602,"0/0","Smo inhibitor","SMO","Hedgehog inhibitor"]
["PPFIA3","GSK_690693",0.478,0.0155,-0.165,0.541,-1.97,0.0494,0.0514,0.602,"+/0","AKT, PKA, PKC inhibitor","AKT1;AKT2;AKT3;PRKCE;PRKCB;PRKCD;PRKCH;PRKCQ;PRKX;PRKG1","Kinase inhibitor"]
["RABL6","Nintedanib",-0.43,0.0318,0.224,0.405,1.97,0.0494,0.0514,0.602,"-/0","VEGFR, PDGFR, FGFR inhibitor","FGFR1;FGFR2;FLT1;FLT4;KDR;PDGFRA;PDGFRB","Kinase inhibitor"]
["PTP4A3","OTS167",0.192,0.359,0.707,0.00218,1.97,0.0494,0.0514,0.602,"0/+","MELK inhibitor","MELK","Kinase inhibitor"]
["RAI1","Mubritinib",0.28,0.176,-0.38,0.146,-1.97,0.0494,0.0514,0.602,"0/0","HER2 inhibitor","ERBB2","Kinase inhibitor"]
["RNF111","GSK2636771",0.0797,0.705,-0.543,0.0299,-1.97,0.0494,0.0514,0.602,"0/-","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["RPL35A","AZD7762",0.165,0.431,-0.478,0.0608,-1.97,0.0494,0.0514,0.602,"0/0","CHEK1 inhibitor","CHEK1;CHEK2","Kinase inhibitor"]
["RPS6","Deferoxamine",0.448,0.0248,-0.203,0.451,-1.97,0.0494,0.0514,0.602,"+/0","Iron chelator","APP","Other"]
["PUS10","AZD1208",-0.471,0.0174,0.174,0.519,1.97,0.0494,0.0514,0.602,"-/0","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["PSMC1","Paclitaxel",0.421,0.036,-0.234,0.383,-1.97,0.0494,0.0514,0.602,"+/0","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;BCL2;MAP2;MAP4;MAPT","Conv.Chemo"]
["RIPOR1","Perifosine",0.165,0.43,-0.478,0.061,-1.97,0.0494,0.0514,0.602,"0/0","AKT, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3","Kinase inhibitor"]
["RPS27","IOX_1",0.308,0.134,-0.353,0.179,-1.97,0.0494,0.0514,0.602,"0/0","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["SELL","Sorafenib",0.186,0.373,-0.461,0.072,-1.97,0.0494,0.0514,0.602,"0/0","BRAF, FGFR-1, VEGFR-2 and -3, PDGFR-beta, KIT, and FLT3 inhibitor","BRAF;FGFR1;KDR;FLT3;KIT;FLT4;PDGFRB","Kinase inhibitor"]
["RBM48","BIIB021",0.119,0.572,-0.514,0.0417,-1.97,0.0494,0.0514,0.602,"0/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["RPA2","Cabazitaxel",-0.409,0.0422,0.248,0.355,1.97,0.0494,0.0514,0.602,"-/0","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["R3HDM2","CC_223",-0.2,0.337,0.45,0.0804,1.97,0.0494,0.0514,0.602,"0/0","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["PUF60","Omaveloxolone",0.251,0.227,-0.407,0.118,-1.97,0.0494,0.0514,0.602,"0/0","Nrf2 activator","NFE2L2","Other"]
["RBBP4","AZD8055",0.229,0.27,-0.425,0.101,-1.97,0.0494,0.0514,0.602,"0/0","mTOR inhibitor","MTOR","Kinase inhibitor"]
["RARA","Selumetinib",-0.403,0.046,0.255,0.34,1.97,0.0494,0.0514,0.602,"-/0","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["PSAT1","Glasdegib",0.0958,0.649,-0.531,0.0343,-1.97,0.0494,0.0514,0.602,"0/-","Smo inhibitor","SMO","Hedgehog inhibitor"]
["RPS28","Lonafarnib",0.295,0.153,-0.366,0.163,-1.97,0.0494,0.0514,0.602,"0/0","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["PPP6R2","Merestinib",-0.106,0.614,-0.661,0.00534,-1.97,0.0494,0.0514,0.602,"0/-","MET inhibitor","MET","Kinase inhibitor"]
["RSL24D1","Selinexor",0.247,0.235,-0.41,0.115,-1.97,0.0494,0.0514,0.602,"0/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["RASAL1","Ixazomib",-0.0402,0.849,-0.622,0.0101,-1.97,0.0494,0.0514,0.602,"0/-","20S proteasome inhibitor","PSMB5","Protease.proteasome inhibitor"]
["PPP3CC","Quizartinib",-0.171,0.413,0.474,0.0639,1.97,0.0494,0.0514,0.602,"0/0","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["PSMD1","C646",0.243,0.241,-0.413,0.112,-1.97,0.0494,0.0514,0.602,"0/0","EP300, CREB-binding protein (CBP) inhibitor","EP300","Differentiating.epigenetic modifier"]
["SCAF11","E7820",0.45,0.0242,-0.201,0.456,-1.97,0.0494,0.0514,0.602,"+/0","Integrin alpha2 expression inhibitor","ITGA2","Other"]
["SAMD8","Lonafarnib",0.14,0.506,-0.498,0.0495,-1.97,0.0494,0.0514,0.602,"0/-","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["RBBP5","Verdinexor",0.476,0.0161,-0.168,0.535,-1.97,0.0494,0.0514,0.602,"+/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["RAB8A","Duvelisib",-0.309,0.133,0.352,0.181,1.97,0.0494,0.0514,0.602,"0/0","PI3K inhibitor","PIK3CD","Kinase inhibitor"]
["POMGNT1","C646",0.144,0.492,-0.495,0.0514,-1.97,0.0494,0.0514,0.602,"0/0","EP300, CREB-binding protein (CBP) inhibitor","EP300","Differentiating.epigenetic modifier"]
["PPP2R1B","Oxaliplatin",0.138,0.509,-0.499,0.049,-1.97,0.0494,0.0514,0.602,"0/-","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["SAMHD1","Alisertib",-0.227,0.275,0.427,0.099,1.97,0.0494,0.0514,0.602,"0/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["RWDD1","Doramapimod",0.41,0.0417,-0.246,0.357,-1.97,0.0494,0.0514,0.602,"+/0","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["SDC1","Niraparib",-0.283,0.17,0.377,0.151,1.97,0.0494,0.0514,0.602,"0/0","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["RABAC1","Tamatinib",0.222,0.285,-0.431,0.0954,-1.97,0.0494,0.0514,0.602,"0/0","SYK inhibitor","SYK","Kinase inhibitor"]
["PPP3CB","GSK2256098",0.351,0.085,-0.31,0.243,-1.97,0.0494,0.0514,0.602,"0/0","FAK inhibitor","PTK2","Kinase inhibitor"]
["RNF213","Deferoxamine",-0.217,0.298,0.436,0.0914,1.97,0.0494,0.0514,0.602,"0/0","Iron chelator","APP","Other"]
["RPS7","Tozasertib",0.388,0.0553,-0.271,0.31,-1.96,0.0494,0.0514,0.602,"0/0","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["RPS23","Daporinad",0.287,0.164,-0.373,0.154,-1.96,0.0494,0.0514,0.602,"0/0","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["REV1","AMG_232",0.347,0.0891,-0.314,0.236,-1.96,0.0494,0.0514,0.602,"0/0","MDM2 inhibitor","MDM2;TP53","Apoptotic modulator"]
["RNF24","Lovastatin",-0.175,0.404,0.471,0.0658,1.96,0.0494,0.0514,0.602,"0/0","HMG-CoA reductase inhibitor","HMGCR","Metabolic modifier"]
["RANGAP1","Talazoparib",0.277,0.18,-0.382,0.144,-1.96,0.0494,0.0514,0.602,"0/0","PARP1 and 2 inhibitor","PARP1;PARP2","Differentiating.epigenetic modifier"]
["RFC5","Alisertib",0.232,0.265,-0.423,0.102,-1.96,0.0494,0.0514,0.602,"0/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["PPP1CB","Methotrexate",0.232,0.264,-0.423,0.103,-1.96,0.0494,0.0514,0.602,"0/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor","DHFR;TYMS","Metabolic modifier"]
["RAD18","Tubacin",0.439,0.0283,-0.214,0.427,-1.96,0.0494,0.0514,0.602,"+/0","HDAC6 inhibitor","HDAC6","Differentiating.epigenetic modifier"]
["RRP1","Lonafarnib",0.155,0.459,-0.486,0.0562,-1.96,0.0494,0.0514,0.602,"0/0","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["SCMH1","Sunitinib",0.167,0.425,-0.477,0.0619,-1.96,0.0494,0.0515,0.602,"0/0","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["RPRD1B","SGC_CBP30",0.198,0.342,-0.451,0.0793,-1.96,0.0494,0.0515,0.602,"0/0","CREBBP, EP300 bromodomain inhibitor","CREBBP","Differentiating.epigenetic modifier"]
["PTGFRN","Resminostat",0.258,0.213,-0.4,0.125,-1.96,0.0494,0.0515,0.602,"0/0","HDAC1, 3, 6 inhibitor","HDAC1;HDAC3;HDAC6","Differentiating.epigenetic modifier"]
["PSRC1","Tucidinostat",0.286,0.166,-0.374,0.154,-1.96,0.0494,0.0515,0.602,"0/0","HDAC1, 2, 3 and 10 inhibitor","HDAC1;HDAC2;HDAC3;HDAC10","Differentiating.epigenetic modifier"]
["RPS5","NVP_RAF265",-0.201,0.335,0.449,0.0811,1.96,0.0494,0.0515,0.602,"0/0","C-Raf inhibitor, unclear MoA","RAF1;BRAF;KDR","Kinase inhibitor"]
["RPRD1B","Raltitrexed",-0.693,0.000123,-0.165,0.541,1.96,0.0494,0.0515,0.602,"-/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["SCD5","AZD3965",-0.12,0.566,0.513,0.0423,1.96,0.0494,0.0515,0.602,"0/+","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["POLR3F","Fluorouracil",0.181,0.387,-0.466,0.0692,-1.96,0.0495,0.0515,0.602,"0/0","Antimetabolite, Pyrimidine analog, interferes with DNA synthesis","TYMS","Conv.Chemo"]
["ROCK1","Bosutinib",-0.00943,0.964,0.59,0.0161,1.96,0.0495,0.0515,0.602,"0/+","ABL, Src inhibitor","ABL1;LYN;HCK;SRC;EPHB2;NTRK1;NTRK2;TXK","Kinase inhibitor"]
["QSOX1","Birinapant",-0.117,0.577,0.515,0.0412,1.96,0.0495,0.0515,0.602,"0/+","IAPs, SMAC mimetic","XIAP;BIRC2;BIRC3","Apoptotic modulator"]
["RPS18","Vistusertib",0.538,0.0055,-0.0853,0.754,-1.96,0.0495,0.0515,0.602,"+/0","mTOR inhibitor, ATP-competitive","MTOR","Kinase inhibitor"]
["RETREG1","Cisplatin",-0.135,0.52,0.502,0.0477,1.96,0.0495,0.0515,0.602,"0/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["SCYL1","AMG_232",-0.357,0.08,0.304,0.252,1.96,0.0495,0.0515,0.602,"0/0","MDM2 inhibitor","MDM2;TP53","Apoptotic modulator"]
["PYCR3","TGX_221",-0.184,0.38,0.463,0.0707,1.96,0.0495,0.0515,0.602,"0/0","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["PTPRG","VE_821",-0.183,0.382,0.464,0.0703,1.96,0.0495,0.0515,0.602,"0/0","ATR inihibitor","ATR","Kinase inhibitor"]
["PRKAR1B","Taladegib",0.1,0.634,-0.528,0.0357,-1.96,0.0495,0.0515,0.602,"0/-","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["SEMA4C","Belinostat",0.199,0.341,0.711,0.00202,1.96,0.0495,0.0515,0.602,"0/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["PTPMT1","IOX_2",-0.521,0.00755,0.109,0.688,1.96,0.0495,0.0515,0.602,"-/0","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["RAD18","AZD_1080",0.313,0.128,-0.348,0.186,-1.96,0.0495,0.0515,0.602,"0/0","GSK3 inhibitor","GSK3B;GSK3A","Kinase inhibitor"]
["RBL2","ZSTK474",-0.444,0.0261,0.207,0.443,1.96,0.0495,0.0515,0.602,"-/0","PI3K gamma selective inhibitor","PIK3CG","Kinase inhibitor"]
["RETREG2","FRAX486",-0.218,0.294,0.434,0.0928,1.96,0.0495,0.0515,0.602,"0/0","PAK1, 2, 3 inhibitor","PAK1","Kinase inhibitor"]
["PURA","Sirolimus",-0.355,0.0819,0.306,0.249,1.96,0.0495,0.0515,0.602,"0/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["PSMF1","Salinomycin",0.46,0.0208,-0.188,0.486,-1.96,0.0495,0.0515,0.602,"+/0","Ionophore","ABCB1","Other"]
["RBM15B","Auranofin",0.0162,0.939,-0.586,0.0171,-1.96,0.0495,0.0515,0.602,"0/-","Antirheumatic agent","PRDX5;IKBKB","Conv.Chemo"]
["RIPK2","Mitomycin_C",0.172,0.411,0.697,0.0027,1.96,0.0495,0.0515,0.602,"0/+","Antineoplastic anatibiotic, DNA crosslinker","DNA","Conv.Chemo"]
["PRMT5","ONX_0914",-0.073,0.729,-0.641,0.00742,-1.96,0.0495,0.0515,0.602,"0/-","LMP7 (immunoproteasome)","PSMB8","Protease.proteasome inhibitor"]
["SCO1","Bleomycin",0.182,0.384,-0.465,0.0699,-1.96,0.0495,0.0515,0.602,"0/0","Glycopeptide antibiotic, causes DNA breaks","DNA","Conv.Chemo"]
["PPP1R15B","UNC0638",0.218,0.295,-0.435,0.0924,-1.96,0.0495,0.0515,0.602,"0/0","G9a, GLP inhibitor","EHMT2","Differentiating.epigenetic modifier"]
["PPFIA3","Vincristine",0.234,0.26,-0.421,0.105,-1.96,0.0495,0.0515,0.602,"0/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB;TUBA4A","Conv.Chemo"]
["RBBP9","LY3009120",-0.25,0.228,0.407,0.118,1.96,0.0495,0.0515,0.602,"0/0","Pan-RAF, (Pan-HER inhibitor)","BRAF;RAF1","Kinase inhibitor"]
["RANBP10","Cytarabine.Idarubicin",0.348,0.0884,0.782,0.000346,1.96,0.0495,0.0515,0.602,"0/+","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["PSMD7","Luminespib",0.0576,0.784,-0.558,0.0248,-1.96,0.0495,0.0515,0.602,"0/-","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["PPP2R3C","AMG_232",0.231,0.267,-0.424,0.102,-1.96,0.0495,0.0515,0.602,"0/0","MDM2 inhibitor","MDM2;TP53","Apoptotic modulator"]
["RRAGC","Megestrol_acetate",-0.151,0.472,0.489,0.0543,1.96,0.0495,0.0515,0.602,"0/0","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["RNF169","Filanesib",0.162,0.44,-0.481,0.0594,-1.96,0.0495,0.0515,0.602,"0/0","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["PSMB1","Pictilisib",0.191,0.36,-0.457,0.0751,-1.96,0.0495,0.0515,0.602,"0/0","PI3K inhibitor, pan-class I","PIK3CA;PIK3CB;PIK3CG;PIK3CD;MTOR","Kinase inhibitor"]
["RRP15","Erastin",0.307,0.136,-0.354,0.178,-1.96,0.0495,0.0515,0.602,"0/0","VDAC inhibitor, induces ferroptosis","VDAC2","Metabolic modifier"]
["RFXAP","Mercaptopurine",-0.536,0.00573,0.0881,0.746,1.96,0.0495,0.0515,0.602,"-/0","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["PTPRE","PIM_447",0.351,0.0851,-0.31,0.243,-1.96,0.0495,0.0515,0.602,"0/0","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["SCRIB","Hydroxyurea",0.466,0.019,-0.181,0.503,-1.96,0.0495,0.0515,0.602,"+/0","Antineoplastic agent","RRM1","Conv.Chemo"]
["RABGAP1","VS_4718",-0.486,0.0138,0.155,0.566,1.96,0.0495,0.0515,0.602,"-/0","FAK inhibitor","PTK2","Kinase inhibitor"]
["RANGRF","Mocetinostat",0.0306,0.884,0.616,0.0111,1.96,0.0495,0.0515,0.602,"0/+","HDAC inhibitor (HDAC1 and 2-selective)","HDAC1;HDAC2;HDAC3;HDAC11","Differentiating.epigenetic modifier"]
["PSMB1","Omacetaxine",-5.8E-4,0.998,-0.597,0.0147,-1.96,0.0495,0.0515,0.602,"0/-","Protein synthesis inhib (80 S ribosome)","RPL3","Conv.Chemo"]
["PSMC2","Saracatinib",0.356,0.0809,-0.305,0.251,-1.96,0.0495,0.0515,0.602,"0/0","Src, ABL inhibitor","ABL1;SRC;LCK;YES1;LYN;FYN;BLK;EGFR;KIT;EPHA2","Kinase inhibitor"]
["RBM26","Carfilzomib",-0.306,0.136,0.354,0.178,1.96,0.0495,0.0515,0.602,"0/0","Proteasome inhibitor (20S subunit)","PSMB5;PSMB8;PSMB1;PSMB2;PSMB9;PSMB10","Protease.proteasome inhibitor"]
["RFX1","Litronesib",-0.445,0.0259,0.206,0.444,1.96,0.0495,0.0515,0.602,"-/0","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["QDPR","Epirubicin",-0.629,0.000762,-0.0522,0.848,1.96,0.0495,0.0515,0.602,"-/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["RASA1","Oxaliplatin",-0.125,0.551,0.509,0.0441,1.96,0.0495,0.0515,0.602,"0/+","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["SCRIB","Docetaxel",0.541,0.00524,-0.0816,0.764,-1.96,0.0495,0.0515,0.602,"+/0","Mitotic inhibitor, taxane microtubule stabilizer","TUBB1;MAP2;MAP4;MAPT","Conv.Chemo"]
["RBM12","Rigosertib",0.223,0.283,-0.43,0.0965,-1.96,0.0495,0.0515,0.602,"0/0","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["RWDD3","Bosutinib",0.171,0.415,-0.474,0.0639,-1.96,0.0495,0.0515,0.602,"0/0","ABL, Src inhibitor","ABL1;LYN;HCK;SRC;EPHB2;NTRK1;NTRK2;TXK","Kinase inhibitor"]
["RPL23A","Pemetrexed",0.731,{"v":3.31e-05,"d":"3.31E-05"},0.239,0.372,-1.96,0.0495,0.0515,0.602,"+/0","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Metabolic modifier"]
["SEC31A","ARV_825",-0.165,0.43,0.478,0.0611,1.96,0.0495,0.0515,0.602,"0/0","BET-targeting PROTAC","BRD4","Differentiating.epigenetic modifier"]
["RPL38","Afuresertib",-0.0377,0.858,0.571,0.0208,1.96,0.0495,0.0515,0.602,"0/+","AKT1-selective inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["PSMD1","Vandetanib",-0.415,0.0391,0.241,0.369,1.96,0.0495,0.0515,0.602,"-/0","VEGFR, EGFR, RET inhibitor","KDR;FLT4;EGFR;RET","Kinase inhibitor"]
["POMGNT2","Pevonedistat",-0.133,0.526,0.503,0.0471,1.96,0.0495,0.0515,0.602,"0/+","NAE inhibitor","NAE1","Metabolic modifier"]
["RB1CC1","Ridaforolimus",0.423,0.0351,-0.231,0.389,-1.96,0.0495,0.0515,0.602,"+/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["RUNDC1","AZD6738",0.264,0.202,-0.394,0.131,-1.96,0.0495,0.0515,0.602,"0/0","ATR inihibitor","ATR","Kinase inhibitor"]
["RPL29","CCT196969",0.231,0.266,-0.423,0.103,-1.96,0.0495,0.0515,0.602,"0/0","pan-RAF, Src inhibitor","RAF1;BRAF;SRC;LCK","Kinase inhibitor"]
["QTRT1","SCH772984",-0.0225,0.915,0.581,0.0182,1.96,0.0495,0.0515,0.602,"0/+","ERK1 and 2 inhibitor","MAPK3","Kinase inhibitor"]
["RACGAP1","BX_912",0.145,0.488,-0.494,0.0521,-1.96,0.0495,0.0515,0.602,"0/0","PDK1 inhibitor","PDK1","Kinase inhibitor"]
["RIOK2","AZD3965",0.408,0.0428,-0.248,0.354,-1.96,0.0495,0.0515,0.602,"+/0","MCT1 inhibitor","SLC16A1","Metabolic modifier"]
["PSMD12","ZSTK474",0.164,0.433,-0.479,0.0606,-1.96,0.0495,0.0515,0.602,"0/0","PI3K gamma selective inhibitor","PIK3CG","Kinase inhibitor"]
["RIF1","Cabozantinib",-0.046,0.827,-0.625,0.00965,-1.96,0.0495,0.0515,0.602,"0/-","VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor","KDR;MET;FLT3;KIT;RET;TEK","Kinase inhibitor"]
["PSMD6","Azacitidine",0.372,0.0667,-0.287,0.28,-1.96,0.0495,0.0516,0.602,"0/0","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["PSMC4","Vinorelbine",0.473,0.017,-0.172,0.525,-1.96,0.0495,0.0516,0.602,"+/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBB","Conv.Chemo"]
["PTDSS1","Tosedostat",0.112,0.595,-0.519,0.0395,-1.96,0.0495,0.0516,0.602,"0/-","Aminopeptidase inhibitor","ANPEP","Protease.proteasome inhibitor"]
["PTPRC","Finasteride",0.0843,0.689,-0.539,0.0313,-1.96,0.0495,0.0516,0.602,"0/-","type II 5-alpha reductase inhibitor","SRD5A2","Hormone therapy"]
["PQBP1","Uprosertib",0.18,0.388,-0.466,0.0691,-1.96,0.0495,0.0516,0.602,"0/0","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["RPA1","GSK_1070916",-0.412,0.0407,0.244,0.363,1.96,0.0495,0.0516,0.602,"-/0","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["PPP3CA","A_419259",-0.327,0.11,0.334,0.206,1.96,0.0495,0.0516,0.602,"0/0","HCK and other SRC family kinase inhibitor","SRC;LCK;LYN;HCK","Kinase inhibitor"]
["POLR3D","Molibresib",0.347,0.0892,-0.314,0.236,-1.96,0.0495,0.0516,0.602,"0/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["PWP1","Sonidegib",0.0467,0.825,0.625,0.00959,1.96,0.0496,0.0516,0.602,"0/+","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["QSER1","Tasquinimod",0.0435,0.836,-0.567,0.0219,-1.96,0.0496,0.0516,0.602,"0/-","S100A9 inhibitor, immunomodulatory, anti-angiogenic","S100A9","Immunomodulatory"]
["PTPRCAP","Panobinostat",0.501,0.0107,-0.135,0.617,-1.96,0.0496,0.0516,0.602,"+/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["PSMD13","Vorinostat",0.477,0.0159,-0.166,0.538,-1.96,0.0496,0.0516,0.602,"+/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["SECISBP2","Sapanisertib",0.411,0.0413,-0.245,0.36,-1.96,0.0496,0.0516,0.602,"+/0","mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["REEP4","CUDC_305",0.207,0.321,-0.444,0.0849,-1.96,0.0496,0.0516,0.602,"0/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["RIOK2","Triciribine",0.208,0.319,-0.443,0.0855,-1.96,0.0496,0.0516,0.602,"0/0","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["PTGR2","VS_4718",0.234,0.26,-0.421,0.105,-1.96,0.0496,0.0516,0.602,"0/0","FAK inhibitor","PTK2","Kinase inhibitor"]
["RNASET2","Gilteritinib",6.45E-3,0.976,0.6,0.014,1.96,0.0496,0.0516,0.602,"0/+","FLT3, AXL inhibitor","FLT3","Kinase inhibitor"]
["RCSD1","Pacritinib",-0.199,0.34,0.45,0.0801,1.96,0.0496,0.0516,0.602,"0/0","FLT3, JAK2 inhibitor","FLT3;JAK2;TYK2","Kinase inhibitor"]
["PRDX1","TAK_530",0.284,0.17,-0.376,0.151,-1.96,0.0496,0.0516,0.602,"0/0","Pan-HER inhibitor","EGFR;ERBB2;ERBB3","Kinase inhibitor"]
["SEC22B","Mivebresib",0.11,0.601,-0.52,0.0388,-1.96,0.0496,0.0516,0.602,"0/-","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["RAB27A","Tivozanib",-0.175,0.402,0.47,0.0663,1.96,0.0496,0.0516,0.602,"0/0","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["RASA2","Losmapimod",-0.413,0.0403,0.243,0.364,1.96,0.0496,0.0516,0.602,"-/0","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["RPL28","Triapine",0.399,0.0482,-0.259,0.334,-1.96,0.0496,0.0516,0.602,"+/0","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["RAP2B","Volasertib",-0.287,0.165,0.373,0.155,1.96,0.0496,0.0516,0.602,"0/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["RNF7","Olaparib",-0.111,0.598,-0.663,0.00512,-1.96,0.0496,0.0516,0.602,"0/-","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["POLR1C","Panobinostat",-0.08,0.704,-0.645,0.00695,-1.96,0.0496,0.0516,0.602,"0/-","HDAC inhibitor","HDAC1;HDAC2;HDAC3","Differentiating.epigenetic modifier"]
["RELCH","Cladribine",-0.405,0.0446,0.252,0.347,1.96,0.0496,0.0516,0.602,"-/0","Antimetabolite, Purine analog","RRM1;RRM2;RRM2B","Conv.Chemo"]
["PRKACA","Bosutinib",-0.223,0.285,0.431,0.096,1.96,0.0496,0.0516,0.602,"0/0","ABL, Src inhibitor","ABL1;LYN;HCK;SRC;EPHB2;NTRK1;NTRK2;TXK","Kinase inhibitor"]
["RAB3GAP2","Erlotinib",0.467,0.0187,-0.179,0.507,-1.96,0.0496,0.0516,0.602,"+/0","EGFR inhibitor","EGFR","Kinase inhibitor"]
["PPM1E","Gedatolisib",0.424,0.0349,-0.231,0.39,-1.96,0.0496,0.0516,0.602,"+/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CG;MTOR","Kinase inhibitor"]
["RABL3","Fludarabine",-0.477,0.0159,0.166,0.539,1.96,0.0496,0.0516,0.602,"-/0","Antimetabolite, Purine analog","RRM1","Conv.Chemo"]
["PPP1R35","Carboplatin",0.295,0.153,-0.366,0.164,-1.96,0.0496,0.0516,0.602,"0/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["SAMD9L","Milciclib",-0.426,0.0337,0.228,0.396,1.96,0.0496,0.0516,0.603,"-/0","CDK2 inhibitor","CDK2;CDK4;CDK5;CDK7;NTRK1","Kinase inhibitor"]
["RAP2A","Bafetinib",-0.279,0.177,0.38,0.146,1.96,0.0496,0.0516,0.603,"0/0","ABL, Lyn inhibitor","ABL1;LYN","Kinase inhibitor"]
["RGS14","IOX_2",0.322,0.116,-0.339,0.2,-1.96,0.0496,0.0516,0.603,"0/0","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["SDHC","Tipifarnib",-0.252,0.225,0.405,0.12,1.96,0.0496,0.0516,0.603,"0/0","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["RPF1","GSK650394",0.214,0.304,-0.438,0.0901,-1.96,0.0496,0.0516,0.603,"0/0","SGK1 and 2 inhibitor","SGK1","Kinase inhibitor"]
["RBBP4","KU_60019",0.255,0.219,-0.402,0.122,-1.96,0.0496,0.0516,0.603,"0/0","ATM inhibitor","ATM","Kinase inhibitor"]
["RIPK2","Selinexor",0.216,0.301,-0.436,0.091,-1.96,0.0496,0.0516,0.603,"0/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["PROM1","Oprozomib",0.589,0.00196,-0.0111,0.968,-1.96,0.0496,0.0516,0.603,"+/0","proteasome (20 S) inhibitor","PSMB5;PSMB8","Protease.proteasome inhibitor"]
["QRICH1","8_amino_adenosine",0.531,0.00634,-0.0954,0.725,-1.96,0.0496,0.0516,0.603,"+/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["PPM1A","Amsacrine",-0.478,0.0155,0.164,0.543,1.96,0.0496,0.0516,0.603,"-/0","DNA intercalation, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA","Conv.Chemo"]
["POLR3F","GSK_461364",0.28,0.175,-0.379,0.148,-1.96,0.0496,0.0516,0.603,"0/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["RRAS","Azacitidine",-0.0278,0.895,-0.614,0.0115,-1.96,0.0496,0.0517,0.603,"0/-","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["SARDH","Ivosidenib",-0.0591,0.779,0.556,0.0252,1.96,0.0496,0.0517,0.603,"0/+","IDH1 R132H and R132C inhibitor","IDH1","Differentiating.epigenetic modifier"]
["SAPCD2","UNC0638",-0.101,0.63,0.526,0.0362,1.96,0.0496,0.0517,0.603,"0/+","G9a, GLP inhibitor","EHMT2","Differentiating.epigenetic modifier"]
["PPP2R3B","Niraparib",0.33,0.107,-0.331,0.211,-1.96,0.0496,0.0517,0.603,"0/0","PARP inhibitor","PARP1","Differentiating.epigenetic modifier"]
["SCD5","Canertinib",-0.133,0.525,0.502,0.0473,1.96,0.0496,0.0517,0.603,"0/+","Pan-HER inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["RBM41","Glesatinib",0.211,0.312,-0.44,0.0878,-1.96,0.0496,0.0517,0.603,"0/0","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["RIPK1","Gemcitabine",-0.517,0.00815,0.114,0.674,1.96,0.0496,0.0517,0.603,"-/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["RCN1","Prexasertib",0.461,0.0204,-0.186,0.49,-1.96,0.0496,0.0517,0.603,"+/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["RAB33A","SN_38",0.0695,0.741,0.639,0.00771,1.96,0.0496,0.0517,0.603,"0/+","Active metabolite of irinotecan, Topoisomerase I inhibitor","TOP1","Conv.Chemo"]
["PPIA","Sunitinib",-0.285,0.168,0.375,0.153,1.96,0.0496,0.0517,0.603,"0/0","Broad TK inhibitor","FLT3;KIT;KDR;PDGFRB;FLT1;FLT4;CSF1R;PDGFRA","Kinase inhibitor"]
["RNF14","Tivozanib",0.273,0.186,-0.385,0.141,-1.96,0.0496,0.0517,0.603,"0/0","VEGFR1, 2, 3, c-Kit, PDGFRB inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB;EPHB2;TEK","Kinase inhibitor"]
["SAT2","Tirabrutinib",-0.265,0.201,0.393,0.132,1.96,0.0496,0.0517,0.603,"0/0","BTK inhibitor","BTK","Kinase inhibitor"]
["PPP1R18","FRAX486",-0.129,0.539,0.506,0.0456,1.96,0.0496,0.0517,0.603,"0/+","PAK1, 2, 3 inhibitor","PAK1","Kinase inhibitor"]
["PPCS","Prexasertib",-0.499,0.0111,0.138,0.611,1.96,0.0496,0.0517,0.603,"-/0","CHEK1 inhibitor","CHEK1","Kinase inhibitor"]
["RTN1","Entinostat",-0.423,0.0349,0.231,0.39,1.96,0.0496,0.0517,0.603,"-/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["PRKAG2","GSK_1070916",-0.372,0.0672,0.288,0.28,1.96,0.0496,0.0517,0.603,"0/0","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["RRP36","Lonafarnib",0.215,0.303,-0.437,0.0905,-1.96,0.0496,0.0517,0.603,"0/0","Farnesyl transferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["PTPN13","Acalabrutinib",-0.475,0.0164,0.168,0.533,1.96,0.0496,0.0517,0.603,"-/0","BTK inhibitor","BTK","Kinase inhibitor"]
["PORCN","CC_223",-0.36,0.0769,0.3,0.259,1.96,0.0496,0.0517,0.603,"0/0","mTOR inhibitor","MTOR;CSF1R","Kinase inhibitor"]
["PPP1R3E","Gemcitabine",-0.409,0.0425,0.247,0.356,1.96,0.0496,0.0517,0.603,"-/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["PSMB1","BMS863233",0.155,0.461,-0.486,0.0563,-1.96,0.0496,0.0517,0.603,"0/0","Cdc7 inhibitor","CDC7","Kinase inhibitor"]
["PSMD14","Ribociclib",0.54,0.00535,-0.0826,0.761,-1.96,0.0497,0.0517,0.603,"+/0","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["PRELID3B","Nintedanib",0.0306,0.885,-0.576,0.0196,-1.96,0.0497,0.0517,0.603,"0/-","VEGFR, PDGFR, FGFR inhibitor","FGFR1;FGFR2;FLT1;FLT4;KDR;PDGFRA;PDGFRB","Kinase inhibitor"]
["RHBDD2","AZD1152_HQPA",0.25,0.229,-0.407,0.118,-1.96,0.0497,0.0517,0.603,"0/0","Aurora B inhibitor","AURKB","Kinase inhibitor"]
["PPFIA3","Tirabrutinib",-0.164,0.433,0.478,0.0609,1.96,0.0497,0.0517,0.603,"0/0","BTK inhibitor","BTK","Kinase inhibitor"]
["SDHA","Ibrutinib",-0.254,0.22,0.402,0.122,1.96,0.0497,0.0517,0.603,"0/0","BTK inhibitor","BTK;BLK;EGFR;FYN;LYN;LCK;BRAF;WNK1","Kinase inhibitor"]
["RFX3","Prednisolone",0.13,0.535,-0.505,0.0462,-1.96,0.0497,0.0517,0.603,"0/-","Glucocorticoid, immunomodulatory agent","NR3C1","Immunomodulatory"]
["SEC31A","Vandetanib",-0.325,0.113,0.336,0.203,1.96,0.0497,0.0517,0.603,"0/0","VEGFR, EGFR, RET inhibitor","KDR;FLT4;EGFR;RET","Kinase inhibitor"]
["PRIM2","AZD_1080",0.2,0.338,-0.449,0.0807,-1.96,0.0497,0.0517,0.603,"0/0","GSK3 inhibitor","GSK3B;GSK3A","Kinase inhibitor"]
["RAPGEF5","E7820",0.287,0.164,-0.373,0.155,-1.96,0.0497,0.0517,0.603,"0/0","Integrin alpha2 expression inhibitor","ITGA2","Other"]
["RAC1","Altiratinib",-0.151,0.471,0.489,0.0548,1.96,0.0497,0.0517,0.603,"0/0","MET, Tie-2 inhibitor","MET;NTRK1;NTRK3;NTRK2;TEK;FLT3;KIT;KDR","Kinase inhibitor"]
["RAF1","Filgotinib",0.317,0.123,-0.344,0.192,-1.96,0.0497,0.0517,0.603,"0/0","JAK1-selective inhibitor","JAK1;JAK2;TYK2","Kinase inhibitor"]
["RAD51D","Givinostat",-0.0774,0.713,0.543,0.0296,1.96,0.0497,0.0517,0.603,"0/+","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC10","Differentiating.epigenetic modifier"]
["SEMA4A","Selinexor",-0.459,0.0211,0.189,0.484,1.96,0.0497,0.0517,0.603,"-/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["SDR39U1","Cisplatin",-0.575,0.00267,0.0324,0.905,1.96,0.0497,0.0517,0.603,"-/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["RPL13A","AZD_8186",0.303,0.141,-0.357,0.174,-1.96,0.0497,0.0517,0.603,"0/0","PI3K beta inhibitor","PIK3CG","Kinase inhibitor"]
["PPP1R13B","Danusertib",-0.535,0.00589,0.0896,0.741,1.96,0.0497,0.0517,0.603,"-/0","Aurora, Ret, TrkA, FGFR-1 inhibitor","AURKA;AURKB;RET;FGFR1;ABL1;NTRK1","Kinase inhibitor"]
["RPL7L1","Palomid_529",-0.0471,0.823,0.565,0.0227,1.96,0.0497,0.0517,0.603,"0/+","AKT, MTOR, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3;MTOR","Kinase inhibitor"]
["POLR3C","MK_8745",0.321,0.118,-0.34,0.198,-1.96,0.0497,0.0517,0.603,"0/0","Aurora A inhibitor","AURKA","Kinase inhibitor"]
["RCOR3","Losmapimod",-0.247,0.234,0.409,0.116,1.96,0.0497,0.0517,0.603,"0/0","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["PRRC2C","Ibrutinib",0.368,0.0705,-0.292,0.272,-1.96,0.0497,0.0517,0.603,"0/0","BTK inhibitor","BTK;BLK;EGFR;FYN;LYN;LCK;BRAF;WNK1","Kinase inhibitor"]
["RPF2","Acalabrutinib",0.199,0.34,-0.45,0.0801,-1.96,0.0497,0.0517,0.603,"0/0","BTK inhibitor","BTK","Kinase inhibitor"]
["RPS4X","AZD_6482",0.212,0.308,-0.439,0.0889,-1.96,0.0497,0.0517,0.603,"0/0","PI3K beta selective inhibitor","PIK3CB","Kinase inhibitor"]
["RBM48","Vinblastine",0.0577,0.784,0.632,0.00866,1.96,0.0497,0.0517,0.603,"0/+","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["PTPN4","Vorinostat",0.156,0.456,-0.485,0.057,-1.96,0.0497,0.0517,0.603,"0/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["PSMB5","Cytarabine.Idarubicin",0.408,0.0428,-0.248,0.355,-1.96,0.0497,0.0517,0.603,"+/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["RUVBL1","A_1331852",-0.304,0.139,0.356,0.176,1.96,0.0497,0.0517,0.603,"0/0","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2;MCL1","Apoptotic modulator"]
["RAB10","Givinostat",-0.388,0.0552,0.27,0.312,1.96,0.0497,0.0517,0.603,"0/0","HDAC inhibitor","HDAC1;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC10","Differentiating.epigenetic modifier"]
["PTPN22","Mitoxantrone",-0.35,0.0864,0.311,0.242,1.96,0.0497,0.0517,0.603,"0/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["PRPF18","AT9283",0.21,0.314,-0.441,0.0872,-1.96,0.0497,0.0517,0.603,"0/0","Aurora A and B, Jak2, Flt, ABL inhibitor","AURKA;AURKB;JAK2;JAK3;ABL1;ABL2;FGFR2;GSK3B;MERTK;FLT4;FLT1;RPS6KA3;RPS6KA2;RET;TYK2;YES1;FGFR1;PDGFRA;FLT1;STK17A;RPS6KA6;FLT3;KDR;SRC","Kinase inhibitor"]
["PPP3CC","Selinexor",0.207,0.321,-0.443,0.0853,-1.96,0.0497,0.0517,0.603,"0/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["PRMT6","AZD_8186",-0.245,0.237,0.41,0.114,1.96,0.0497,0.0517,0.603,"0/0","PI3K beta inhibitor","PIK3CG","Kinase inhibitor"]
["RCC2","PF_03758309",0.286,0.165,-0.373,0.155,-1.96,0.0497,0.0517,0.603,"0/0","PAK4 inhibitor","PAK4","Kinase inhibitor"]
["PPP1R14B","8_amino_adenosine",0.593,1.8E-3,-0.00476,0.986,-1.96,0.0497,0.0517,0.603,"+/0","Antimetabolite, Nucleoside analog, RNA synthesis inhibitor","RNA","Conv.Chemo"]
["SCAF11","AZD_5438",0.36,0.0775,-0.301,0.258,-1.96,0.0497,0.0517,0.603,"0/0","CDK1, 2, 9 inhibitor","CDK1;CDK2;CDK9","Kinase inhibitor"]
["RACGAP1","Amuvatinib",0.312,0.129,-0.348,0.186,-1.96,0.0497,0.0517,0.603,"0/0","Broad TK inhibitor","KIT;PDGFRA;FLT3","Kinase inhibitor"]
["PPP1R9B","Axitinib",-0.215,0.302,0.437,0.0909,1.96,0.0497,0.0517,0.603,"0/0","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["SCAF1","Carfilzomib",0.345,0.0914,-0.316,0.234,-1.96,0.0497,0.0517,0.603,"0/0","Proteasome inhibitor (20S subunit)","PSMB5;PSMB8;PSMB1;PSMB2;PSMB9;PSMB10","Protease.proteasome inhibitor"]
["PPP1R14B","AZD_5363",-0.0511,0.808,0.562,0.0236,1.96,0.0497,0.0517,0.603,"0/+","AKT inhibitor","AKT1;AKT2;AKT3;ROCK2","Kinase inhibitor"]
["RASSF3","TAK_901",0.448,0.0249,-0.202,0.453,-1.96,0.0497,0.0517,0.603,"+/0","Aurora, Src family, JAK3, RTK inhibitor","AURKA;AURKB;JAK3;SRC;CLK2;FGR;LRRK2;YES1;LCK;FYN;ABL1;AXL;ABL2;HCK;RET;FRK;NTRK1;FGFR2","Kinase inhibitor"]
["PPP1R13B","GSK269962",-0.09,0.669,0.534,0.033,1.96,0.0497,0.0518,0.603,"0/+","ROCK1 and ROCK2 inhibitor","ROCK1;ROCK2;RPS6KA5;RPS6KA1","Kinase inhibitor"]
["PSMD11","ML390",0.569,2.98E-3,-0.04,0.883,-1.96,0.0497,0.0518,0.603,"+/0","DHODH inhibitor","DHODH","Differentiating.epigenetic modifier"]
["RPN1","Litronesib",-0.262,0.206,0.395,0.13,1.96,0.0497,0.0518,0.603,"0/0","Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["PPCS","ABT_751",-0.527,0.00678,0.1,0.713,1.96,0.0497,0.0518,0.603,"-/0","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["SEC61A1","Temsirolimus",-0.274,0.185,0.384,0.142,1.96,0.0497,0.0518,0.603,"0/0","binds FKBP12, causes inhibition of mTORC1","FKBP1A","Rapalog"]
["RNF14","Foretinib",0.0828,0.694,-0.539,0.031,-1.96,0.0497,0.0518,0.603,"0/-","MET, VEGFR2 inhibitor","MET;KDR","Kinase inhibitor"]
["S100A9","NVP_LCL161",0.37,0.069,-0.29,0.276,-1.96,0.0497,0.0518,0.603,"0/0","IAPs, SMAC mimetic","XIAP;BIRC2","Apoptotic modulator"]
["POP4","Epirubicin",-0.395,0.0505,0.262,0.327,1.96,0.0497,0.0518,0.603,"0/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["RHBDD2","Abemaciclib",0.176,0.399,-0.469,0.0671,-1.96,0.0497,0.0518,0.603,"0/0","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["SAMM50","E7820",-0.616,0.00105,-0.032,0.906,1.96,0.0498,0.0518,0.603,"-/0","Integrin alpha2 expression inhibitor","ITGA2","Other"]
["SCLT1","Carboplatin",0.566,0.0032,-0.0451,0.868,-1.96,0.0498,0.0518,0.603,"+/0","Platinum-based antineoplastic agent","DNA","Conv.Chemo"]
["RPS8","Itraconazole",0.357,0.0796,-0.303,0.254,-1.96,0.0498,0.0518,0.603,"0/0","antifungal, hedgehog signaling inhibitor","CYP51A1;CYP3A4","Other"]
["RPL30","Glesatinib",0.128,0.541,-0.506,0.0456,-1.96,0.0498,0.0518,0.603,"0/-","MET, AXL, TIE, VEGFR, RON inhibitor","MET;MST1R;KDR;FLT4;TEK","Kinase inhibitor"]
["RUFY3","Quizartinib",0.132,0.53,0.674,0.00416,1.96,0.0498,0.0518,0.603,"0/+","FLT3 inhibitor","FLT3","Kinase inhibitor"]
["SBF2","Triciribine",-0.421,0.0359,0.233,0.386,1.96,0.0498,0.0518,0.603,"-/0","AKT inhibitor","AKT1;AKT2;AKT3","Kinase inhibitor"]
["PSTK","PF_03758309",0.0929,0.659,-0.532,0.0338,-1.96,0.0498,0.0518,0.603,"0/-","PAK4 inhibitor","PAK4","Kinase inhibitor"]
["PSMF1","Regorafenib",-0.405,0.0445,0.251,0.349,1.96,0.0498,0.0518,0.603,"-/0","BRAF, c-Kit, VEGFR2 inhibitor","BRAF;RAF1;KIT;KDR;FLT1;RET;PDGFRB;FLT4","Kinase inhibitor"]
["SARDH","Spebrutinib",0.104,0.621,0.659,0.00551,1.96,0.0498,0.0518,0.603,"0/+","BTK inhibitor","BTK","Kinase inhibitor"]
["SEMA4C","Buparlisib",0.589,0.00195,-0.0102,0.97,-1.96,0.0498,0.0518,0.603,"+/0","PI3K inhibitor, pan-class I","PIK3CA;PIK3CB;PIK3CG;PIK3CD;MTOR;PIK3C3","Kinase inhibitor"]
["SBDS","NVP_CGM097",-0.383,0.0591,0.276,0.301,1.96,0.0498,0.0518,0.603,"0/0","p53-MDM2 inhibitor","TP53;MDM2","Apoptotic modulator"]
["RNF169","Acitretin",-0.0716,0.734,-0.64,0.00759,-1.96,0.0498,0.0518,0.603,"0/-","Retinoic acid receptor agonist","RARA;RARB;RXRA;RXRB;RXRG","Differentiating.epigenetic modifier"]
["RACK1","Trifluridine",0.668,0.000262,0.12,0.657,-1.96,0.0498,0.0518,0.603,"+/0","Antimetabolite, Nucleoside analog","TYMS","Conv.Chemo"]
["RRP1B","BMS_911543",0.312,0.129,-0.349,0.186,-1.96,0.0498,0.0518,0.603,"0/0","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["SAP30BP","NVP_BHG712",-0.265,0.201,0.393,0.132,1.96,0.0498,0.0518,0.603,"0/0","EphB4 inhibitor","EPHB4","Kinase inhibitor"]
["RFXANK","Volasertib",-0.338,0.0985,0.323,0.223,1.96,0.0498,0.0518,0.603,"0/0","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["REXO2","BMS_911543",0.51,0.00918,-0.123,0.651,-1.96,0.0498,0.0518,0.603,"+/0","JAK2 inhibitor","JAK2;SETD2;TYK2;JAK3","Kinase inhibitor"]
["RCN2","Exemestane",-0.448,0.0248,0.201,0.454,1.96,0.0498,0.0518,0.603,"-/0","Aromatase inhibitor","CYP19A1","Hormone therapy"]
["RAB9B","Mitoxantrone",0.246,0.236,-0.41,0.115,-1.96,0.0498,0.0518,0.603,"0/0","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["RPS6KB2","Pevonedistat",-0.221,0.29,0.432,0.0949,1.96,0.0498,0.0518,0.603,"0/0","NAE inhibitor","NAE1","Metabolic modifier"]
["POLR3K","Axitinib",0.423,0.035,-0.23,0.391,-1.96,0.0498,0.0518,0.603,"+/0","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["RUBCNL","PIM_447",0.4,0.0476,-0.257,0.337,-1.96,0.0498,0.0518,0.603,"+/0","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["RSPRY1","Raltitrexed",0.0921,0.662,-0.533,0.0336,-1.96,0.0498,0.0518,0.603,"0/-","Antimetabolite, Antifolate, Dihydrofolate reductase inhibitor, thymidylate synthase inhibitor","TYMS;DHFR","Conv.Chemo"]
["PPM1F","TAK_530",0.208,0.319,-0.442,0.0862,-1.96,0.0498,0.0518,0.603,"0/0","Pan-HER inhibitor","EGFR;ERBB2;ERBB3","Kinase inhibitor"]
["PRKRIP1","IOX_2",0.251,0.226,-0.405,0.12,-1.96,0.0498,0.0518,0.603,"0/0","PHD2 inhibitor","EGLN1","Differentiating.epigenetic modifier"]
["PPP1R37","PAC_1",-0.15,0.474,0.489,0.0545,1.96,0.0498,0.0518,0.603,"0/0","procaspase-3 activator","CASP3","Apoptotic modulator"]
["PTGR2","Losmapimod",-0.412,0.0406,0.243,0.364,1.96,0.0498,0.0518,0.603,"-/0","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["POLR3C","Clomifene",0.109,0.606,-0.521,0.0387,-1.96,0.0498,0.0518,0.603,"0/-","Selective estrogen receptor modulator","ESR1;SHBG","Hormone therapy"]
["PPIA","GSK2656157",0.297,0.149,-0.362,0.168,-1.96,0.0498,0.0518,0.603,"0/0","PERK inhibitor","EIF2AK3","Kinase inhibitor"]
["PTPRS","Gedatolisib",0.296,0.151,-0.364,0.166,-1.96,0.0498,0.0518,0.603,"0/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CG;MTOR","Kinase inhibitor"]
["PSMD1","Triapine",0.364,0.0741,-0.296,0.266,-1.96,0.0498,0.0518,0.603,"0/0","ribonucleotide reductase inhibitor","RRM1;RRM2","Metabolic modifier"]
["SECISBP2L","Seliciclib",0.312,0.129,-0.348,0.186,-1.96,0.0498,0.0518,0.603,"0/0","CDK2, 7, 9 inhibitor","CDK2;CDK1;CDK5;MAPK1;MAPK3","Kinase inhibitor"]
["RABL6","Selumetinib",0.442,0.0268,-0.208,0.44,-1.96,0.0498,0.0518,0.603,"+/0","MEK1 and 2 inhibitor","MAP2K1","Kinase inhibitor"]
["RANGAP1","Megestrol_acetate",-0.0548,0.795,0.559,0.0244,1.96,0.0498,0.0519,0.603,"0/+","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["RALGAPA1","Cytarabine.Idarubicin",-0.341,0.0956,0.32,0.228,1.96,0.0498,0.0519,0.603,"0/0","Antimetabolite, interferes with DNA synthesis, Topoisomerase II inhibitor","TOP2A;TOP2B;DNA;POLB","Other"]
["RILPL1","Enzalutamide",-0.26,0.209,0.397,0.128,1.96,0.0498,0.0519,0.603,"0/0","AR antagonist","AR","Hormone therapy"]
["RMND1","Vinblastine",-0.388,0.0551,0.27,0.313,1.96,0.0498,0.0519,0.603,"0/0","Mitotic inhibitor, Vinca alkaloid microtubule depolymerizer","TUBA1A;TUBB;TUBD1;TUBG1;TUBE1","Conv.Chemo"]
["RIPK1","ENMD_2076",-0.418,0.0376,0.236,0.378,1.96,0.0498,0.0519,0.603,"-/0","pan-Aurora, VEGFR inhibitor","AURKA;FLT3;RET;FLT4;SRC;CSF1R;NTRK1;PDGFRA;BLK;KDR;YES1;FYN;AURKB;PTK2;FGFR2;FGFR1;JAK2;KIT;ABL1","Kinase inhibitor"]
["PWP1","Taselisib",0.38,0.0609,-0.278,0.296,-1.96,0.0498,0.0519,0.603,"0/0","PI3K alpha, delta, (gamma) selective inhibitor","PIK3CA;PIK3CD;PIK3CG","Kinase inhibitor"]
["PSMB7","GSK650394",0.0428,0.839,-0.567,0.022,-1.96,0.0498,0.0519,0.603,"0/-","SGK1 and 2 inhibitor","SGK1","Kinase inhibitor"]
["RBM23","Filgotinib",-0.279,0.177,0.38,0.147,1.96,0.0498,0.0519,0.603,"0/0","JAK1-selective inhibitor","JAK1;JAK2;TYK2","Kinase inhibitor"]
["RNF181","Tipifarnib",0.347,0.0894,-0.313,0.237,-1.96,0.0498,0.0519,0.603,"0/0","Farnesyltransferase inhibitor","FNTA","Differentiating.epigenetic modifier"]
["RTRAF","PS_1145",0.334,0.102,-0.326,0.218,-1.96,0.0498,0.0519,0.603,"0/0","IKK-2 inhibitor","IKBKB","Kinase inhibitor"]
["RPUSD3","Palomid_529",-0.107,0.612,0.522,0.0381,1.96,0.0499,0.0519,0.603,"0/+","AKT, MTOR, PI3K inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;AKT1;AKT2;AKT3;MTOR","Kinase inhibitor"]
["QSOX1","Tozasertib",-0.0262,0.901,0.578,0.019,1.96,0.0499,0.0519,0.603,"0/+","pan-Aurora inhibitor","AURKA;AURKB;AURKC;FLT3;ABL1","Kinase inhibitor"]
["RIOX1","Ravoxertinib",-0.0583,0.782,-0.632,0.00865,-1.96,0.0499,0.0519,0.603,"0/-","ERK inhibitor","MAPK3","Kinase inhibitor"]
["RBM39","Simvastatin",0.377,0.0632,-0.282,0.29,-1.96,0.0499,0.0519,0.603,"0/0","HMG CoA reductase inhibitor","HMGCR","Metabolic modifier"]
["REXO2","Mercaptopurine",0.174,0.405,-0.47,0.0661,-1.96,0.0499,0.0519,0.603,"0/0","Antimetabolite, Purine analog","HPRT1;PPAT","Conv.Chemo"]
["SEMA4D","Epirubicin",0.258,0.213,0.74,1.06E-3,1.96,0.0499,0.0519,0.603,"0/+","Topoisomerase II inhibitor","TOP2A;TOP2B","Conv.Chemo"]
["PREPL","Taladegib",0.266,0.198,-0.391,0.134,-1.96,0.0499,0.0519,0.603,"0/0","Smothened (Hh) inhibitor","SMO","Hedgehog inhibitor"]
["RPS27","AZD1208",-0.129,0.539,-0.673,0.00429,-1.96,0.0499,0.0519,0.603,"0/-","PIM1, 2, 3 kinase inhibitor","PIM1","Kinase inhibitor"]
["RCOR2","GSK_1070916",0.283,0.171,-0.376,0.151,-1.96,0.0499,0.0519,0.603,"0/0","Aurora B, Aurora C inhibitor","AURKB;AURKC","Kinase inhibitor"]
["POTEF","ENMD_2076",-0.384,0.0577,0.274,0.305,1.96,0.0499,0.0519,0.603,"0/0","pan-Aurora, VEGFR inhibitor","AURKA;FLT3;RET;FLT4;SRC;CSF1R;NTRK1;PDGFRA;BLK;KDR;YES1;FYN;AURKB;PTK2;FGFR2;FGFR1;JAK2;KIT;ABL1","Kinase inhibitor"]
["RRM2","Entinostat",0.36,0.0771,-0.3,0.259,-1.96,0.0499,0.0519,0.603,"0/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["RNF5","Mivebresib",0.248,0.231,-0.407,0.117,-1.96,0.0499,0.0519,0.603,"0/0","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["SENP8","Aldoxorubicin",-0.342,0.0942,0.318,0.23,1.96,0.0499,0.0519,0.603,"0/0","Topoisomerase II inhibitor, Albumin binding","TOP2A;TOP2B","Conv.Chemo"]
["SAC3D1","Palbociclib",0.0927,0.659,-0.532,0.0339,-1.96,0.0499,0.0519,0.603,"0/-","Topoisomerase I inhibitor, Camptothecin analog","CDK4;CDK6","Kinase inhibitor"]
["RPL26","Vistusertib",0.134,0.522,-0.501,0.048,-1.96,0.0499,0.0519,0.603,"0/-","mTOR inhibitor, ATP-competitive","MTOR","Kinase inhibitor"]
["PSMD4","Quisinostat",0.326,0.112,-0.334,0.206,-1.96,0.0499,0.0519,0.603,"0/0","HDAC inhibitor","HDAC1;HDAC2;HDAC4;HDAC10;HDAC11","Differentiating.epigenetic modifier"]
["RNF170","CPI_0610",0.0865,0.681,-0.537,0.0321,-1.96,0.0499,0.0519,0.603,"0/-","BET family inhibitor","BRD2;BRD3;BRD4","Differentiating.epigenetic modifier"]
["SCAF11","MST_312",0.455,0.0222,-0.192,0.475,-1.96,0.0499,0.0519,0.603,"+/0","Telomerase inhibitor","TERT","Other"]
["PPP1R16B","Axitinib",-0.267,0.197,0.391,0.135,1.96,0.0499,0.0519,0.603,"0/0","VEGFR, PDGFR, KIT inhibitor","KDR;FLT1;FLT4;KIT;PDGFRA;PDGFRB","Kinase inhibitor"]
["PRKAR2B","AMG_925",-0.495,0.0118,0.142,0.6,1.96,0.0499,0.0519,0.603,"-/0","FLT3, CDK4 inhibitor","FLT3;CDK4","Kinase inhibitor"]
["PPP2R5D","AZD1775",0.00323,0.988,-0.593,0.0154,-1.96,0.0499,0.0519,0.603,"0/-","Wee1 inhibitor","WEE1","Kinase inhibitor"]
["PURB","Cabazitaxel",-0.485,0.014,0.155,0.567,1.96,0.0499,0.0519,0.603,"-/0","Mitotic inhibitor, taxane microtubule stabilizer, antimitotic","TUBB1;TUBA4A","Conv.Chemo"]
["PTPN13","Verdinexor",0.191,0.361,-0.456,0.0756,-1.96,0.0499,0.0519,0.603,"0/0","XPO1 CRM1 inhibitor","XPO1","Apoptotic modulator"]
["RHOA","AZD8055",-0.461,0.0203,0.185,0.493,1.96,0.0499,0.0519,0.603,"-/0","mTOR inhibitor","MTOR","Kinase inhibitor"]
["RPL12","Vactosertib_TEW_7197",-0.0669,0.751,0.55,0.0272,1.96,0.0499,0.0519,0.603,"0/+","TGF receptor ALK4, ALK5 inhibitor","TGFBR1;ACVR1B","Kinase inhibitor"]
["POLR1E","A_1331852",-0.438,0.0284,0.212,0.43,1.96,0.0499,0.0519,0.603,"-/0","Bcl-XL inhibitor","BCL2L1;BCL2;BCL2L2;MCL1","Apoptotic modulator"]
["RAB35","PS_1145",-0.17,0.417,0.473,0.064,1.96,0.0499,0.0519,0.603,"0/0","IKK-2 inhibitor","IKBKB","Kinase inhibitor"]
["SEC14L1","Vactosertib_TEW_7197",-0.267,0.198,0.391,0.135,1.96,0.0499,0.0519,0.603,"0/0","TGF receptor ALK4, ALK5 inhibitor","TGFBR1;ACVR1B","Kinase inhibitor"]
["PRTFDC1","Ixazomib",-0.553,0.00418,0.0638,0.815,1.96,0.0499,0.0519,0.603,"-/0","20S proteasome inhibitor","PSMB5","Protease.proteasome inhibitor"]
["SCAMP3","Fingolimod",0.602,1.47E-3,0.00968,0.972,-1.96,0.0499,0.0519,0.603,"+/0","S1PR antagonist","S1PR1","Other"]
["PRDX2","Pexidartinib",-0.412,0.0407,0.243,0.365,1.96,0.0499,0.0519,0.603,"-/0","KIT, CSF1R, FLT3 inhibitor","CSF1R;FLT3;KIT","Kinase inhibitor"]
["RTEL1","Megestrol_acetate",0.437,0.029,-0.214,0.425,-1.96,0.0499,0.0519,0.603,"+/0","Progestogen","PGR;AR;NR3C1;ESR1","Hormone therapy"]
["PRAG1","Deferoxamine",-0.184,0.378,0.462,0.0718,1.96,0.0499,0.0519,0.603,"0/0","Iron chelator","APP","Other"]
["REL","Rigosertib",-0.417,0.0382,0.238,0.376,1.96,0.0499,0.0519,0.603,"-/0","PLK1 Inhibitor, Ras-Raf interaction inhibitor, contaminated by microtubile depolymerizer","PLK1;SRC;FLT1;PDGFRB;ABL1","Other"]
["RAB5B","Filanesib",-0.282,0.172,0.377,0.151,1.96,0.0499,0.0519,0.603,"0/0","KSP, Eg5 inhibitor","KIF11","Kinesin inhibitor"]
["PTPN23","Mubritinib",-0.318,0.121,0.342,0.195,1.96,0.0499,0.0519,0.603,"0/0","HER2 inhibitor","ERBB2","Kinase inhibitor"]
["R3HCC1","Vorinostat",0.478,0.0156,-0.164,0.544,-1.96,0.0499,0.0519,0.603,"+/0","HDAC inhibitor","HDAC1;HDAC3","Differentiating.epigenetic modifier"]
["POLR1D","GDC_0084",0.422,0.0356,-0.231,0.388,-1.96,0.0499,0.0519,0.603,"+/0","PI3K, mTOR inhibitor","PIK3CA;PIK3CB;PIK3CD;PIK3CG;MTOR","Kinase inhibitor"]
["RPL23A","Varlitinib",0.295,0.152,-0.364,0.165,-1.96,0.0499,0.0519,0.603,"0/0","EGFR HER2 inhibitor","EGFR;ERBB2","Kinase inhibitor"]
["PSMD11","Decitabine",0.492,0.0124,-0.146,0.59,-1.96,0.0499,0.052,0.603,"+/0","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["PTGES2","Lovastatin",-0.281,0.174,0.378,0.149,1.96,0.0499,0.052,0.603,"0/0","HMG-CoA reductase inhibitor","HMGCR","Metabolic modifier"]
["RASSF2","ONX_0914",0.735,{"v":2.86e-05,"d":"2.86E-05"},0.248,0.354,-1.96,0.0499,0.052,0.603,"+/0","LMP7 (immunoproteasome)","PSMB8","Protease.proteasome inhibitor"]
["SBDS","Losmapimod",-0.348,0.0882,0.312,0.24,1.96,0.0499,0.052,0.603,"0/0","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["RANBP6","Losmapimod",0.487,0.0136,-0.153,0.572,-1.96,0.0499,0.052,0.603,"+/0","p38MAPK inhibitor","MAPK14","Kinase inhibitor"]
["PTPN11","Daporinad",-0.22,0.291,0.432,0.0947,1.96,0.0499,0.052,0.603,"0/0","NAMPT inhibitor","NAMPT","Metabolic modifier"]
["RPL6","BAY_87_2243",0.0213,0.919,0.609,0.0123,1.96,0.0499,0.052,0.603,"0/+","HIF1alpha inhibitor","HIF1A","Differentiating.epigenetic modifier"]
["RPP30","Midostaurin",0.145,0.488,-0.493,0.0525,-1.96,0.0499,0.052,0.603,"0/0","Broad TK (FLT3, KIT, RET, JAK, EGFR) inhibitor","PRKCA;PRKCB;PRKCG;FLT3;KIT;RET;EGFR;JAK1;KDR","Kinase inhibitor"]
["PPP1CB","BIIB021",-0.539,0.00541,0.0826,0.761,1.96,0.0499,0.052,0.603,"-/0","HSP90 inhibitor","HSP90AA1","HSP inhibitor"]
["RCOR3","ABT_751",-0.613,0.00112,-0.028,0.918,1.96,0.0499,0.052,0.603,"-/0","Mitotic inhibitor, Colchicine site binding microtubule depolymerizer","TUBB","Conv.Chemo"]
["RBL1","Ribociclib",-0.549,0.00444,0.0681,0.802,1.96,0.0499,0.052,0.603,"-/0","CDK4, 6 inhibitor","CDK4;CDK6","Kinase inhibitor"]
["RCC1L","BMS_754807",-0.343,0.0932,0.317,0.232,1.96,0.0499,0.052,0.603,"0/0","IGF1R inhibitor","IGF1R","Kinase inhibitor"]
["RPL34","AZD_8186",0.351,0.0849,-0.308,0.245,-1.96,0.0499,0.052,0.603,"0/0","PI3K beta inhibitor","PIK3CG","Kinase inhibitor"]
["RAB11A","Decitabine",0.0705,0.738,-0.548,0.028,-1.96,0.0499,0.052,0.603,"0/-","Antimetabolite, Nucleoside analog, DNA methyl transferase inhibitor","TYMS","Differentiating.epigenetic modifier"]
["RALGPS2","Sitravatinib",-0.541,0.0052,0.0796,0.769,1.96,0.0499,0.052,0.603,"-/0","RET, TRK, PDGFR, VEGFR, KIT, DDR inhibitor","DDR2;RET;KIT;EPHA3;AXL;MERTK;NTRK1;FLT1;FLT3;FLT4;KDR;NTRK2;EPHB2;EPHB4;MST1R;RET;PDGFRA;DDR1;EPHA2;EPHA4;SRC;ROS1","Kinase inhibitor"]
["RPL27A","IOX_1",0.265,0.2,-0.392,0.133,-1.96,0.0499,0.052,0.603,"0/0","2-Oxoglutarate Oxygenase Inhibitor","KDM3A;KDM4C;KDM6B;KDM2A;KDM4E;KDM5C;EGLN1","Differentiating.epigenetic modifier"]
["POLR2D","SGC_CBP30",0.186,0.374,-0.461,0.0726,-1.96,0.0499,0.052,0.603,"0/0","CREBBP, EP300 bromodomain inhibitor","CREBBP","Differentiating.epigenetic modifier"]
["RER1","GSK_461364",-0.0606,0.774,0.555,0.0257,1.96,0.0499,0.052,0.603,"0/+","PLK1 inhibitor","PLK1","Kinase inhibitor"]
["SENP7","Omacetaxine",0.455,0.0224,-0.193,0.475,-1.96,0.0499,0.052,0.603,"+/0","Protein synthesis inhib (80 S ribosome)","RPL3","Conv.Chemo"]