{"text_format":"3","workbook":"xlsx","n_sheets":8,"sheets":["Seurat","ProjectTIL","CD8 Tex","Th1","Treg","CD8 EM","CD8 Tpex","CD8 EA"],"read":"whole","date_system":"1900"}

{"sheet":"Seurat","index":0,"n_rows":18,"n_cols":7,"rows_kept":18}
["Cluster","Average frequency","Untreated","CTLA4","RT","RT+CTLA4","Differentially expressed genes (adjusted p-value < 0.01, average fold change > 2, percent of cells in cluster expressing gene > 0.6)"]
[0,{"$f":"AVERAGE(C2:F2)","v":{"v":0.26276041675,"d":"26.3%"}},{"v":0.307291667,"d":"30.7%"},{"v":0.209375,"d":"20.9%"},{"v":0.333333333,"d":"33.3%"},{"v":0.201041667,"d":"20.1%"},"Cd8a, Cd8b1, Ctsd, Gzma, Gzmb, Klra5, Klrc1, Lgals3, Nkg7, Pdcd1, Spp1, Trgv2"]
[1,{"v":0.11770833324999999,"d":"11.8%"},{"v":0.081770833,"d":"8.2%"},{"v":0.109375,"d":"10.9%"},{"v":0.075,"d":"7.5%"},{"v":0.2046875,"d":"20.5%"},"Ccl5, Gzmk, Ly6c1, Ly6c2"]
[2,{"v":0.1177083335,"d":"11.8%"},{"v":0.143229167,"d":"14.3%"},{"v":0.141145833,"d":"14.1%"},{"v":0.126041667,"d":"12.6%"},{"v":0.060416667,"d":"6.0%"},"Ahr, Areg, Arl5a, Arl5c, Ass1, Batf, Ccr2, Ccr7, Ccrl2, Cd5, Cd81, Cd83, Cebpb, Cmtm7, Ctla4, Cxcr4, Dgat2, Dusp1, Fabp5, Foxp3, Gadd45b, Gm2a, Got1, Icam1, Ier5, Ifi27l2a, Ikzf2, Ikzf4, Il1rl1, Il2ra, Itgae, Itgb7, Itm2c, Izumo1r, Klrg1, Lmna, Ltb, Ly6a, Maf, Mxd1, Nfkbia, Nfkbiz, Nr4a1, Penk, Pim1, Ppp1r15a, Psen2, Rel, Rilpl2, Rora, Rrad, Samhd1, Sdc4, Sell, Slc25a19, Snx18, Stx11, Syngr2, Tgif1, Tigit, Tnfrsf18, Tnfrsf4, Tnfrsf9, Traf1, Trp53i11, Vim, Zfp36, Zfp36l1"]
[3,{"v":0.10559895799999999,"d":"10.6%"},{"v":0.064583333,"d":"6.5%"},{"v":0.167708333,"d":"16.8%"},{"v":0.030208333,"d":"3.0%"},{"v":0.159895833,"d":"16.0%"},"Bhlhe40, Ccl1, Ccr8, Cd4, Cd40lg, Cd82, Cd83, Csf2, Emb, Fabp5, Furin, Igfbp7, Il13, Il1r2, Krt83, Lgals7, Lta, Nfkbid, Penk, Prnp, Ramp3, Scin, Tnfsf11, Tnfsf8"]
[4,{"v":0.07434895849999999,"d":"7.4%"},{"v":0.108854167,"d":"10.9%"},{"v":0.085416667,"d":"8.5%"},{"v":0.049479167,"d":"4.9%"},{"v":0.053645833,"d":"5.4%"},"Dusp10, Ecm1, Klf2, Klf3, Pja1, Ramp3, S1pr1, Socs3, Tbc1d4, Tcf7"]
[5,{"v":0.0630208335,"d":"6.3%"},{"v":0.060416667,"d":"6.0%"},{"v":0.0484375,"d":"4.8%"},{"v":0.086979167,"d":"8.7%"},{"v":0.05625,"d":"5.6%"},"Dut, Mcm3, Mcm5, Mcm6, Stmn1"]
[6,{"v":0.0419270835,"d":"4.2%"},{"v":0.038020833,"d":"3.8%"},{"v":0.033854167,"d":"3.4%"},{"v":0.041666667,"d":"4.2%"},{"v":0.054166667,"d":"5.4%"},"Ccl1, Ccl3, Ccl4, Cd8a, Ifng, Irf8, Nr4a2, Rgs16, Xcl1"]
[7,{"v":0.0412760415,"d":"4.1%"},{"v":0.030208333,"d":"3.0%"},{"v":0.036458333,"d":"3.6%"},{"v":0.058333333,"d":"5.8%"},{"v":0.040104167,"d":"4.0%"},"Anapc5, Anp32b, Asf1b, Aurkb, Birc5, Ccdc34, Ccna2, Ccnb2, Cdca3, Cdca8, Cdk1, Cenpa, Cenpe, Cenpf, Cenpw, Cks1b, Clspn, Dek, Dut, Esco2, Ezh2, Fbxo5, Gm4316, Gmnn, H2afv, H2afx, H2afz, Hist1h1b, Hist1h1e, Hist1h2ae, Hist1h2ap, Hmgb1, Hmgb2, Hmgn2, Hnrnpab, Incenp, Knl1, Lmnb1, Ly6e, Mcm7, Mki67, Nrm, Nusap1, Pclaf, Pcna, Prc1, Ptma, Pttg1, Racgap1, Rad51, Ran, Rrm1, Rrm2, Selenoh, Siva1, Slbp, Smc2, Smc4, Spc24, Stmn1, Tacc3, Tcf19, Tk1, Tmpo, Top2a, Tpx2, Tuba1b, Tubb4b, Tubb5, Tyms, Ube2c, Ube2s, Uhrf1"]
[8,{"v":0.03515625,"d":"3.5%"},{"v":0.046875,"d":"4.7%"},{"v":0.0421875,"d":"4.2%"},{"v":0.023958333,"d":"2.4%"},{"v":0.027604167,"d":"2.8%"},"Ass1, Bmyc, Cd81, Cmtm7, Ctsz, Fabp5, Foxp3, H2afz, Ikzf2, Il1r2, Il2ra, Klrg1, Ly6a, Mki67, Penk, Rln3, Stmn1, Stx11, Tnfrsf4, Tuba1b, Tubb5"]
[9,{"v":0.03320312475,"d":"3.3%"},{"v":0.028645833,"d":"2.9%"},{"v":0.022395833,"d":"2.2%"},{"v":0.0421875,"d":"4.2%"},{"v":0.039583333,"d":"4.0%"},"Aftph, Bst2, Cmpk2, Cxcl10, Daxx, Dtx3l, Eif2ak2, Gbp2, Gbp4, Gbp7, Gbp9, Herc6, Ifi203, Ifi208, Ifi209, Ifi214, Ifi27l2a, Ifi47, Ifih1, Ifit1, Ifit3, Ifit3b, Igtp, Irf7, Isg15, Isg20, Mndal, Ms4a4b, Mx1, Oas3, Parp14, Phf11b, Rnf213, Rsad2, Rtp4, Samhd1, Slfn1, Slfn5, Slfn8, Stat1, Tgtp2, Tor3a, Trafd1, Trim30a, Ube2l6, Usp18, Xaf1, Zbp1"]
[10,{"v":0.02994791675,"d":"3.0%"},{"v":0.026041667,"d":"2.6%"},{"v":0.023958333,"d":"2.4%"},{"v":0.043229167,"d":"4.3%"},{"v":0.0265625,"d":"2.7%"},"Birc5, Ccnb2, Cenpa, Cks1b, Dap, Hmgb2, Hmgn2, Ly6e, Mt1, Pttg1, Selenoh, Ube2c"]
[11,{"v":0.02513020825,"d":"2.5%"},{"v":0.019270833,"d":"1.9%"},{"v":0.0421875,"d":"4.2%"},{"v":0.010416667,"d":"1.0%"},{"v":0.028645833,"d":"2.9%"},"Cd40lg, Dusp10, Ecm1, Ell2, Fam46a, Gata3, Il1rl1, Il4, Ldha, Lgals7, Myo6, Nfkbia, Pdlim1, Ramp3, Rgs1, Tnfsf8"]
[12,{"v":0.021484375,"d":"2.1%"},{"v":0.016145833,"d":"1.6%"},{"v":0.015104167,"d":"1.5%"},{"v":0.033333333,"d":"3.3%"},{"v":0.021354167,"d":"2.1%"},"Ctsd, Gzma, Gzmb, Gzmc, Gzmd, Gzme, Gzmf, Gzmg, Ifitm1, Irf8, Klra5, Lgals3, Mt1, Prf1, S100a6, Spp1"]
[13,{"v":0.020963541750000002,"d":"2.1%"},{"v":0.011979167,"d":"1.2%"},{"v":0.009375,"d":"0.9%"},{"v":0.0390625,"d":"3.9%"},{"v":0.0234375,"d":"2.3%"},"Ahr, Areg, Bhlhe40, Ccr7, Cd4, Cd81, Ctla4, Ecm1, Ern1, Foxp3, Ikzf2, Il2ra, Itgae, Itgb7, Izumo1r, Lamc1, Ly75, Maf, Malat1, Myh9, Neat1, Nfkbiz, Pim1, Rel, Rora, Samhd1, Sdc4, Sell, Sema4b, Snx18, Stat1, Stat3, Swap70, Zfp36l1"]
[14,{"v":0.003906250000000001,"d":"0.4%"},{"v":0.006770833,"d":"0.7%"},{"v":0.0046875,"d":"0.5%"},{"v":0.002604167,"d":"0.3%"},{"v":0.0015625,"d":"0.2%"},"Aif1, Apoe, C1qa, C1qb, C1qc, Cd63, Cd74, Ctsz, Fcer1g, Fcgr2b, Fcgr3, Gatm, Grn, H2-Aa, H2-Ab1, H2-Eb1, Il1b, Lgmn, Lyz2, Tgfbi, Tyrobp"]
[15,{"v":3.2552084999999996E-3,"d":"0.3%"},{"v":0.003645833,"d":"0.4%"},{"v":0.004166667,"d":"0.4%"},{"v":0.004166667,"d":"0.4%"},{"v":1.041667E-3,"d":"0.1%"},"Car2, Cd160, Cd7, Emid1, Fcer1g, Igha, Klra5, Klra7, Plac8, S100a1, Tyrobp, Xcl1"]
[16,{"v":2.6041667500000002E-3,"d":"0.3%"},{"v":0.00625,"d":"0.6%"},{"v":0.004166667,"d":"0.4%"},{"v":0,"d":"0.0%"},{"v":0,"d":"0.0%"},"Actn2, Avpi1, Cd69, Ckb, Emb, Espn, Ffar2, Furin, Gm2a, Gpx1, Gzmb, Ifngr2, Il17a, Il17re, Il23r, Kctd12, Krt83, Lgals3, Lmo4, Ltb4r1, Myc, Nfkbia, Pim1, Prr29, Pxdc1, Ramp1, Selenop, Serpinb1a, Smox, Tcrg-C1, Tgm2, Tiparp, Tmem176a, Tmem176b, Tnf, Tnfsf14, Zbtb16, Zfp36l1"]

{"sheet":"ProjectTIL","index":1,"n_rows":10,"n_cols":7,"rows_kept":10}
["Cluster","Average frequency","Untreated","CTLA4","RT","RT+CTLA4","Differentially expressed genes (adjusted p-value < 0.01, average fold change > 2, percent of cells in cluster expressing gene > 0.6)"]
["CD8_Tex",{"$f":"AVERAGE(C2:F2)","v":{"v":0.42265625,"d":"42.3%"}},{"v":0.4328125,"d":"43.3%"},{"v":0.304166667,"d":"30.4%"},{"v":0.5984375,"d":"59.8%"},{"v":0.355208333,"d":"35.5%"},"Cd8a, Cd8b1, Cst7, Ctsd, Gzma, Gzmb, Ifitm1, Irf8, Klra5, Klrc1, Klrd1, Lat2, Lgals3, Mt1, Nkg7, Pdcd1, Prf1, Spp1, Trgv2"]
["Th1",{"v":0.24374999975,"d":"24.4%"},{"v":0.209895833,"d":"21.0%"},{"v":0.361458333,"d":"36.1%"},{"v":0.0984375,"d":"9.8%"},{"v":0.305208333,"d":"30.5%"},"Cd4, Cd40lg, Ecm1, Emb, Klf2, Krt83, Lgals7, Lta, Ramp3, Tnfsf11, Tnfsf8"]
["Treg",{"v":0.13632812500000002,"d":"13.6%"},{"v":0.1765625,"d":"17.7%"},{"v":0.146875,"d":"14.7%"},{"v":0.155729167,"d":"15.6%"},{"v":0.066145833,"d":"6.6%"},"Ahr, Areg, Arl5a, Arl5c, Ass1, Batf, Bmyc, Ccr2, Ccr7, Ccr8, Ccrl2, Cd5, Cd81, Cd83, Cmtm7, Ctla4, Ctsz, Ddit4, Dgat2, Dusp1, Fabp5, Foxp3, Gadd45b, Glrx, Gm2a, Icam1, Ifi27l2a, Ikzf2, Ikzf4, Il1r2, Il1rl1, Il2ra, Itgae, Itgb7, Itm2c, Izumo1r, Klrg1, Laptm4b, Lmna, Ltb, Ly6a, Maf, Mxd1, Nfkbia, Nfkbiz, Nr4a1, Penk, Pim1, Rel, Rilpl2, Rln3, Rora, Rrad, Samhd1, Sdc4, Sell, Slc25a19, Snx18, Stat1, Stx11, Syngr2, Tigit, Tnfrsf18, Tnfrsf4, Tnfrsf9, Traf1, Trp53i11, Vim, Zfp36l1"]
["CD8_EffectorMemory",{"v":0.09921875,"d":"9.9%"},{"v":0.0609375,"d":"6.1%"},{"v":0.080208333,"d":"8.0%"},{"v":0.090625,"d":"9.1%"},{"v":0.165104167,"d":"16.5%"},"Ccl5, Gzmk, Ly6c1, Ly6c2"]
["CD8_Tpex",{"v":0.0348958335,"d":"3.5%"},{"v":0.027604167,"d":"2.8%"},{"v":0.036458333,"d":"3.6%"},{"v":0.016666667,"d":"1.7%"},{"v":0.058854167,"d":"5.9%"},"Ccl1, Ccr7, Ifng, Irf8, Nr4a2, Rgs16, Xcl1"]
["CD8_NaiveLike",{"v":0.028125,"d":"2.8%"},{"v":0.047916667,"d":"4.8%"},{"v":0.033333333,"d":"3.3%"},{"v":0.019791667,"d":"2.0%"},{"v":0.011458333,"d":"1.1%"},"Klf2, Ly6c1, Ly6c2"]
["CD8_EarlyActiv",{"v":0.0154947915,"d":"1.5%"},{"v":0.011458333,"d":"1.1%"},{"v":0.015625,"d":"1.6%"},{"v":0.006770833,"d":"0.7%"},{"v":0.028125,"d":"2.8%"},"Ccl5, Cd69, Dusp2, Gramd3, Klf2, Ly6c1, Ly6c2, Zfp36l2"]
["CD4_NaiveLike",{"v":0.012500000249999999,"d":"1.3%"},{"v":0.022916667,"d":"2.3%"},{"v":0.011979167,"d":"1.2%"},{"v":0.0125,"d":"1.3%"},{"v":0.002604167,"d":"0.3%"},"Ccr7, Dusp10, Ecm1, Gramd3, Klf2, Klf3, Lef1, Pja1, Ramp3, S1pr1, Socs3, Tcf7, Trbv20, Trib2"]
["Tfh",{"v":0.007031249999999999,"d":"0.7%"},{"v":0.009895833,"d":"1.0%"},{"v":0.009895833,"d":"1.0%"},{"v":1.041667E-3,"d":"0.1%"},{"v":0.007291667,"d":"0.7%"},"Ccr7, Tnfrsf4, Zfp36l1"]

{"sheet":"CD8 Tex","index":2,"n_rows":9,"n_cols":8,"rows_kept":9}
["Cluster","Proportion of total cells","Proportion of CD8_Tex cells","Untreated","CTLA4","RT","RT+CTLA4","Differentially expressed genes (adjusted p-value < 0.01, average fold change > 2, percent of cells in cluster expressing gene > 0.6)"]
["CD8_Tex",{"$f":"AVERAGE(D2:G2)","v":{"v":0.42265624999999996,"d":"42.3%"}},{"$f":"B2/$B$2","v":{"v":1,"d":"100.0%"}},{"v":0.4328125,"d":"43.3%"},{"v":0.30416667,"d":"30.4%"},{"v":0.5984375,"d":"59.8%"},{"v":0.35520833,"d":"35.5%"},"Cd8a, Cd8b1, Cst7, Ctsd, Gzma, Gzmb, Ifitm1, Irf8, Klra5, Klrc1, Klrd1, Lat2, Lgals3, Mt1, Nkg7, Pdcd1, Prf1, Spp1, Trgv2"]
["CD8_Tex..0",{"v":0.241015625,"d":"24.1%"},{"$f":"B3/$B$2","v":{"v":0.5702402957486138,"d":"57.0%"}},{"v":0.29270833,"d":"29.3%"},{"v":0.18072917,"d":"18.1%"},{"v":0.3140625,"d":"31.4%"},{"v":0.1765625,"d":"17.7%"},"Cd8a, Cd8b1, Ctsd, Gzma, Gzmb, Klra5, Klrc1, Lgals3, Nkg7, Pdcd1, Spp1, Trgv2"]
["CD8_Tex..1",{"v":0.0135416675,"d":"1.4%"},{"v":0.032039435120147876,"d":"3.2%"},{"v":0.0046875,"d":"0.5%"},{"v":0.0046875,"d":"0.5%"},{"v":0.0203125,"d":"2.0%"},{"v":0.02447917,"d":"2.4%"},"NA"]
["CD8_Tex..5",{"v":0.05507812499999999,"d":"5.5%"},{"v":0.13031423290203326,"d":"13.0%"},{"v":0.04479167,"d":"4.5%"},{"v":0.040625,"d":"4.1%"},{"v":0.0828125,"d":"8.3%"},{"v":0.05208333,"d":"5.2%"},"Dut, Mcm3, Mcm5, Mcm6, Stmn1"]
["CD8_Tex..6",{"v":0.0174479175,"d":"1.7%"},{"v":0.04128157929759705,"d":"4.1%"},{"v":0.01822917,"d":"1.8%"},{"v":0.009375,"d":"0.9%"},{"v":0.02708333,"d":"2.7%"},{"v":0.01510417,"d":"1.5%"},"NA"]
["CD8_Tex..7",{"v":0.03606771,"d":"3.6%"},{"v":0.08533580184842886,"d":"8.5%"},{"v":0.025,"d":"2.5%"},{"v":0.028125,"d":"2.8%"},{"v":0.05572917,"d":"5.6%"},{"v":0.03541667,"d":"3.5%"},"Anapc5, Anp32b, Asf1b, Aurkb, Birc5, Ccdc34, Ccna2, Ccnb2, Cdca3, Cdca8, Cdk1, Cenpa, Cenpe, Cenpf, Cenpw, Cks1b, Clspn, Dek, Dnajc9, Dut, Esco2, Ezh2, Fbxo5, Fen1, Gm4316, Gmnn, H2afv, H2afx, H2afz, Hist1h1b, Hist1h1e, Hist1h2ae, Hist1h2ak, Hist1h2ap, Hmgb1, Hmgb2, Hmgn2, Hnrnpa3, Hnrnpab, Incenp, Knl1, Lmnb1, Lsm2, Ly6e, Mcm5, Mcm7, Mki67, Nrm, Nusap1, Pclaf, Pcna, Prc1, Ptma, Pttg1, Racgap1, Rad51, Ran, Rrm1, Rrm2, Selenoh, Siva1, Slbp, Smc2, Smc4, Snrpd1, Spc24, Stmn1, Tacc3, Tcf19, Tk1, Tmpo, Top2a, Tpx2, Tuba1b, Tubb4b, Tubb5, Tyms, Ube2c, Ube2s, Uhrf1"]
["CD8_Tex..10",{"v":0.025651040000000003,"d":"2.6%"},{"v":0.06069007615526804,"d":"6.1%"},{"v":0.021875,"d":"2.2%"},{"v":0.02083333,"d":"2.1%"},{"v":0.040625,"d":"4.1%"},{"v":0.01927083,"d":"1.9%"},"Ccnb2, Cenpa, Dap, Hmgn2, Ly6e, Mt1, Pttg1, Selenoh, Ube2c"]
["CD8_Tex..12",{"v":0.0209635425,"d":"2.1%"},{"v":0.0495995090573013,"d":"5.0%"},{"v":0.01614583,"d":"1.6%"},{"v":0.01354167,"d":"1.4%"},{"v":0.0328125,"d":"3.3%"},{"v":0.02135417,"d":"2.1%"},"Ctsd, Gzma, Gzmb, Gzmc, Gzmd, Gzme, Gzmf, Gzmg, Ifitm1, Irf8, Klra5, Lgals3, Mt1, Prf1, S100a6, Spp1"]

{"sheet":"Th1","index":3,"n_rows":7,"n_cols":9,"rows_kept":7}
["Cluster","Average frequency","Proportion of Th1 cells","Untreated","CTLA4","RT","RT+CTLA4","Differentially expressed genes (adjusted p-value < 0.01, average fold change > 2, percent of cells in cluster expressing gene > 0.6)"]
["Th1",{"$f":"AVERAGE(D2:G2)","v":{"v":0.2437499975,"d":"24.4%"}},{"$f":"B2/$B$2","v":{"v":1,"d":"100.0%"}},{"v":0.20989583,"d":"21.0%"},{"v":0.36145833,"d":"36.1%"},{"v":0.0984375,"d":"9.8%"},{"v":0.30520833,"d":"30.5%"},"Cd4, Cd40lg, Ecm1, Emb, Klf2, Krt83, Lgals7, Lta, Ramp3, Tnfsf11, Tnfsf8"]
["Th1..1",{"v":0.015234375000000001,"d":"1.5%"},{"$f":"B3/$B$2","v":{"v":0.06250000064102565,"d":"6.3%"}},{"v":0.0109375,"d":"1.1%"},{"v":0.0171875,"d":"1.7%"},{"v":0.0046875,"d":"0.5%"},{"v":0.028125,"d":"2.8%"},"Cd69, Ifitm2, Ifitm3, Klf2"]
["Th1..2",{"v":0.02109375,"d":"2.1%"},{"v":0.08653846242603551,"d":"8.7%"},{"v":0.01875,"d":"1.9%"},{"v":0.0359375,"d":"3.6%"},{"v":0.015625,"d":"1.6%"},{"v":0.0140625,"d":"1.4%"},"Ass1, Cxcr4, Dusp1, Foxp3, Ikzf2, Itgb7, Izumo1r, Klf2, Nfkbia, Nfkbiz, Pim1, Ppp1r15a, Rrad, Samhd1, Sell, Snx18, Tgif1, Tnfrsf4, Zfp36, Zfp36l1"]
["Th1..3",{"v":0.10065104250000001,"d":"10.1%"},{"v":0.41292735808130626,"d":"41.3%"},{"v":0.06041667,"d":"6.0%"},{"v":0.16197917,"d":"16.2%"},{"v":0.028125,"d":"2.8%"},{"v":0.15208333,"d":"15.2%"},"Bhlhe40, Ccl1, Ccr8, Cd4, Cd40lg, Cd82, Cd83, Csf2, Emb, Fabp5, Furin, Igfbp7, Il13, Il1r2, Krt83, Lgals7, Lta, Nfkbid, Penk, Prnp, Ramp3, Scin, Tnfsf11, Tnfsf8"]
["Th1..4",{"v":0.05,"d":"5.0%"},{"v":0.2051282072320842,"d":"20.5%"},{"v":0.06979167,"d":"7.0%"},{"v":0.06302083,"d":"6.3%"},{"v":0.02864583,"d":"2.9%"},{"v":0.03854167,"d":"3.9%"},"Cd4, Dusp10, Ecm1, Emb, Klf2, Klf3, Ramp3, Rgs1, S1pr1, Socs3, Tbc1d4, Tcf7"]
["Th1..11",{"v":0.0238281275,"d":"2.4%"},{"v":0.09775642151545047,"d":"9.8%"},{"v":0.01875,"d":"1.9%"},{"v":0.04010417,"d":"4.0%"},{"v":0.01041667,"d":"1.0%"},{"v":0.02604167,"d":"2.6%"},"Cd40lg, Cdkn1a, Dusp10, Ecm1, Ell2, Emb, Fam46a, Gata3, Il1rl1, Il4, Ldha, Lgals7, Myo6, Nfkbia, Pdlim1, Pim1, Ramp3, Rgs1, Tnfsf8","Gata3 is transcription factor for Th2 cells. Th2 cells produce Il4"]

{"sheet":"Treg","index":4,"n_rows":4,"n_cols":8,"rows_kept":4}
["Cluster","Proportion of total cells","Proportion of Treg cells","Untreated","CTLA4","RT","RT+CTLA4","Differentially expressed genes (adjusted p-value < 0.01, average fold change > 2, percent of cells in cluster expressing gene > 0.6)"]
["Treg",{"$f":"AVERAGE(D2:G2)","v":{"v":0.136328125,"d":"13.6%"}},{"$f":"B2/$B$2","v":{"v":1,"d":"100.0%"}},{"v":0.1765625,"d":"17.7%"},{"v":0.146875,"d":"14.7%"},{"v":0.15572917,"d":"15.6%"},{"v":0.06614583,"d":"6.6%"},"Ahr, Areg, Arl5a, Arl5c, Ass1, Batf, Bmyc, Ccr2, Ccr7, Ccr8, Ccrl2, Cd5, Cd81, Cd83, Cmtm7, Ctla4, Ctsz, Ddit4, Dgat2, Dusp1, Fabp5, Foxp3, Gadd45b, Glrx, Gm2a, Icam1, Ifi27l2a, Ikzf2, Ikzf4, Il1r2, Il1rl1, Il2ra, Itgae, Itgb7, Itm2c, Izumo1r, Klrg1, Laptm4b, Lmna, Ltb, Ly6a, Maf, Mxd1, Nfkbia, Nfkbiz, Nr4a1, Penk, Pim1, Rel, Rilpl2, Rln3, Rora, Rrad, Samhd1, Sdc4, Sell, Slc25a19, Snx18, Stat1, Stx11, Syngr2, Tigit, Tnfrsf18, Tnfrsf4, Tnfrsf9, Traf1, Trp53i11, Vim, Zfp36l1"]
["Treg..2",{"$f":"AVERAGE(D3:G3)","v":{"v":0.09505209249999999,"d":"9.5%"}},{"$f":"B3/$B$2","v":{"v":0.6972302487106017,"d":"69.7%"}},{"v":0.1229167,"d":"12.3%"},{"v":0.103125,"d":"10.3%"},{"v":0.10885417,"d":"10.9%"},{"v":0.0453125,"d":"4.5%"},"Ahr, Areg, Arl5a, Arl5c, Ass1, Batf, Bmyc, Ccr2, Ccr7, Ccr8, Ccrl2, Cd5, Cd81, Cd83, Cebpb, Cmtm7, Ctla4, Dgat2, Dusp1, Fabp5, Foxp3, Gadd45b, Glrx, Gm2a, Icam1, Ier5, Ifi27l2a, Ikzf2, Ikzf4, Il1rl1, Il2ra, Itgae, Itgb7, Itm2c, Izumo1r, Klrg1, Laptm4b, Lmna, Ltb, Ly6a, Maf, Mxd1, Nfkbia, Nfkbiz, Nr4a1, Penk, Pim1, Psen2, Rel, Rilpl2, Rora, Rrad, Samhd1, Sdc4, Sell, Slc15a3, Slc25a19, Snx18, Stat1, Stx11, Syngr2, Tgif1, Tigit, Tnfrsf18, Tnfrsf4, Tnfrsf9, Traf1, Trp53i11, Vim, Zfp36, Zfp36l1"]
["Treg..8",{"$f":"AVERAGE(D4:G4)","v":{"v":0.025520835000000002,"d":"2.6%"}},{"v":0.18720154040114614,"d":"18.7%"},{"v":0.040625,"d":"4.1%"},{"v":0.028125,"d":"2.8%"},{"v":0.01979167,"d":"2.0%"},{"v":0.01354167,"d":"1.4%"},"Areg, Ass1, Birc5, Cd81, Cmtm7, Ctla4, Ctsz, Fabp5, Foxp3, H2afz, Ikzf2, Il2ra, Klrg1, Ly6a, Mki67, Penk, Rln3, Stmn1, Tnfrsf4, Tnfrsf9, Tubb5"]

{"sheet":"CD8 EM","index":5,"n_rows":4,"n_cols":8,"rows_kept":4}
["Cluster","Proportion of total cells","Proportion of CD8 EM cells","Untreated","CTLA4","RT","RT+CTLA4","Differentially expressed genes (adjusted p-value < 0.01, average fold change > 2, percent of cells in cluster expressing gene > 0.6)"]
["CD8_EffectorMemory",{"$f":"AVERAGE(D2:G2)","v":{"v":0.09921875,"d":"9.9%"}},{"$f":"B2/$B$2","v":{"v":1,"d":"100.0%"}},{"v":0.0609375,"d":"6.1%"},{"v":0.08020833,"d":"8.0%"},{"v":0.090625,"d":"9.1%"},{"v":0.16510417,"d":"16.5%"},"Ccl5, Gzmk, Ly6c1, Ly6c2"]
["CD8_EffectorMemory..1",{"$f":"AVERAGE(D3:G3)","v":{"v":0.0583333325,"d":"5.8%"}},{"$f":"B3/$B$2","v":{"v":0.5879265007874016,"d":"58.8%"}},{"v":0.03125,"d":"3.1%"},{"v":0.05052083,"d":"5.1%"},{"v":0.0359375,"d":"3.6%"},{"v":0.115625,"d":"11.6%"},"Ccl5, Gzmk, Ly6c1, Ly6c2"]
["CD8_EffectorMemory..9",{"$f":"AVERAGE(D4:G4)","v":{"v":0.015885418249999998,"d":"1.6%"}},{"v":0.16010500283464565,"d":"16.0%"},{"v":0.009895833,"d":"1.0%"},{"v":0.009375,"d":"0.9%"},{"v":0.02760417,"d":"2.8%"},{"v":0.01666667,"d":"1.7%"},"Aftph, Bst2, Ccl5, Cmpk2, Cxcl10, Daxx, Dtx3l, Eif2ak2, Gbp2, Gbp4, Gbp7, Gbp9, Herc6, Ifi203, Ifi208, Ifi209, Ifi214, Ifi47, Ifih1, Ifit1, Ifit2, Ifit3, Igtp, Irf7, Isg15, Isg20, Jaml, Mndal, Ms4a4b, Mx1, Parp14, Phf11b, Rnf213, Rsad2, Rtp4, Samhd1, Slfn1, Slfn8, Stat1, Tgtp2, Tor3a, Trafd1, Trbv3, Trim30a, Ube2l6, Usp18, Xaf1, Zbp1"]

{"sheet":"CD8 Tpex","index":6,"n_rows":3,"n_cols":8,"rows_kept":3}
["Cluster","Proportion of total cells","Proportion of CD8 Tpex cells","Untreated","CTLA4","RT","RT+CTLA4","Differentially expressed genes (adjusted p-value < 0.01, average fold change > 2, percent of cells in cluster expressing gene > 0.6)"]
["CD8_Tpex",{"$f":"AVERAGE(D2:G2)","v":{"v":0.034895835,"d":"3.5%"}},{"$f":"B2/$B$2","v":{"v":1,"d":"100.0%"}},{"v":0.02760417,"d":"2.8%"},{"v":0.03645833,"d":"3.6%"},{"v":0.01666667,"d":"1.7%"},{"v":0.05885417,"d":"5.9%"},"Ccl1, Ccr7, Ifng, Irf8, Nr4a2, Rgs16, Xcl1"]
["CD8_Tpex..6",{"$f":"AVERAGE(D3:G3)","v":{"v":0.021875,"d":"2.2%"}},{"$f":"B3/$B$2","v":{"v":0.6268656417019395,"d":"62.7%"}},{"v":0.0171875,"d":"1.7%"},{"v":0.021875,"d":"2.2%"},{"v":0.01145833,"d":"1.1%"},{"v":0.03697917,"d":"3.7%"},"Ccl1, Ccl3, Ccr7, Cd160, Ifng, Irf8, Nr4a2, Nrgn, Rgs16, Xcl1"]

{"sheet":"CD8 EA","index":7,"n_rows":3,"n_cols":8,"rows_kept":3}
["Cluster","Proportion of total cells","Proportion of CD8 Tpex cells","Untreated","CTLA4","RT","RT+CTLA4","Differentially expressed genes (adjusted p-value < 0.01, average fold change > 2, percent of cells in cluster expressing gene > 0.6)"]
["CD8_EarlyActiv",{"$f":"AVERAGE(D2:G2)","v":{"v":0.0154947915,"d":"1.5%"}},{"$f":"B2/$B$2","v":{"v":1,"d":"100.0%"}},{"v":0.011458333,"d":"1.1%"},{"v":0.015625,"d":"1.6%"},{"v":0.006770833,"d":"0.7%"},{"v":0.028125,"d":"2.8%"},"Ccl5, Cd69, Dusp2, Gramd3, Klf2, Ly6c1, Ly6c2, Zfp36l2"]
["CD8_EarlyActiv..1",{"$f":"AVERAGE(D3:G3)","v":{"v":0.01263020825,"d":"1.3%"}},{"$f":"B3/$B$2","v":{"v":0.8151260538097592,"d":"81.5%"}},{"v":0.008333333,"d":"0.8%"},{"v":0.01458333,"d":"1.5%"},{"v":0.00625,"d":"0.6%"},{"v":0.02135417,"d":"2.1%"},"Ccl5, Cd69, Dusp2, Klf2, Klf6, Ly6c1, Ly6c2, Zfp36l2"]