Analysis Type: PANTHER Overrepresentation Test (Released 20240226) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.10536401 Released 2024-01-17 Analyzed List: upload_1 (Homo sapiens) Reference List: Homo sapiens (all genes in database) Test Type: FISHER Correction: FDR GO biological process complete Homo sapiens - REFLIST (20592) upload_1 (172) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (raw P-value) upload_1 (FDR) regulation of transcription by RNA polymerase II (GO:0006357) 2603 130 21.74 + 5.98 1.06E-80 1.61E-76 regulation of DNA-templated transcription (GO:0006355) 3440 136 28.73 + 4.73 6.16E-73 4.70E-69 regulation of RNA biosynthetic process (GO:2001141) 3459 136 28.89 + 4.71 1.27E-72 6.46E-69 system development (GO:0048731) 3546 136 29.62 + 4.59 3.32E-71 1.27E-67 pattern specification process (GO:0007389) 463 70 3.87 + 18.1 5.21E-70 1.59E-66 multicellular organism development (GO:0007275) 3964 140 33.11 + 4.23 7.45E-70 1.89E-66 animal organ development (GO:0048513) 2869 125 23.96 + 5.22 5.05E-69 1.10E-65 regulation of RNA metabolic process (GO:0051252) 3758 136 31.39 + 4.33 6.64E-68 1.27E-64 regionalization (GO:0003002) 415 66 3.47 + 19.04 3.27E-67 5.53E-64 anatomical structure development (GO:0048856) 5231 149 43.69 + 3.41 1.38E-64 2.10E-61 regulation of nucleobase-containing compound metabolic process (GO:0019219) 4061 136 33.92 + 4.01 1.59E-63 2.20E-60 anatomical structure morphogenesis (GO:0009653) 2239 109 18.7 + 5.83 6.61E-62 8.39E-59 developmental process (GO:0032502) 5739 151 47.94 + 3.15 2.43E-61 2.84E-58 positive regulation of transcription by RNA polymerase II (GO:0045944) 1265 88 10.57 + 8.33 3.30E-60 3.60E-57 animal organ morphogenesis (GO:0009887) 996 79 8.32 + 9.5 1.79E-57 1.82E-54 regulation of gene expression (GO:0010468) 4898 139 40.91 + 3.4 1.96E-56 1.87E-53 embryonic morphogenesis (GO:0048598) 596 65 4.98 + 13.06 3.92E-55 3.52E-52 regulation of macromolecule biosynthetic process (GO:0010556) 5026 139 41.98 + 3.31 5.71E-55 4.83E-52 positive regulation of DNA-templated transcription (GO:0045893) 1711 93 14.29 + 6.51 1.05E-54 8.46E-52 positive regulation of RNA biosynthetic process (GO:1902680) 1714 93 14.32 + 6.5 1.23E-54 9.39E-52 embryo development (GO:0009790) 1059 78 8.85 + 8.82 3.43E-54 2.49E-51 regulation of cellular biosynthetic process (GO:0031326) 5159 139 43.09 + 3.23 1.71E-53 1.18E-50 regulation of biosynthetic process (GO:0009889) 5190 139 43.35 + 3.21 3.72E-53 2.47E-50 positive regulation of RNA metabolic process (GO:0051254) 1852 94 15.47 + 6.08 8.92E-53 5.67E-50 regulation of nitrogen compound metabolic process (GO:0051171) 5474 140 45.72 + 3.06 3.05E-51 1.86E-48 embryonic organ morphogenesis (GO:0048562) 304 50 2.54 + 19.69 6.84E-51 4.01E-48 anterior/posterior pattern specification (GO:0009952) 220 45 1.84 + 24.49 3.33E-50 1.88E-47 regulation of primary metabolic process (GO:0080090) 5622 140 46.96 + 2.98 9.82E-50 5.34E-47 nervous system development (GO:0007399) 2207 97 18.43 + 5.26 3.42E-49 1.80E-46 positive regulation of nucleobase-containing compound metabolic process (GO:0045935) 2059 94 17.2 + 5.47 1.02E-48 5.20E-46 regulation of macromolecule metabolic process (GO:0060255) 6033 142 50.39 + 2.82 7.22E-48 3.55E-45 regulation of cellular metabolic process (GO:0031323) 6054 142 50.57 + 2.81 1.14E-47 5.43E-45 embryonic organ development (GO:0048568) 460 54 3.84 + 14.05 5.77E-47 2.67E-44 regulation of metabolic process (GO:0019222) 6559 143 54.79 + 2.61 3.79E-44 1.70E-41 multicellular organismal process (GO:0032501) 6745 144 56.34 + 2.56 1.41E-43 6.14E-41 positive regulation of macromolecule biosynthetic process (GO:0010557) 2604 97 21.75 + 4.46 8.77E-43 3.71E-40 skeletal system development (GO:0001501) 507 52 4.23 + 12.28 4.46E-42 1.84E-39 positive regulation of cellular biosynthetic process (GO:0031328) 2686 97 22.44 + 4.32 1.34E-41 5.36E-39 positive regulation of biosynthetic process (GO:0009891) 2707 97 22.61 + 4.29 2.65E-41 1.03E-38 cell differentiation (GO:0030154) 3654 109 30.52 + 3.57 1.93E-40 7.37E-38 cellular developmental process (GO:0048869) 3657 109 30.55 + 3.57 2.09E-40 7.78E-38 cell fate commitment (GO:0045165) 256 40 2.14 + 18.71 1.51E-39 5.46E-37 embryonic skeletal system development (GO:0048706) 129 32 1.08 + 29.7 1.54E-38 5.44E-36 central nervous system development (GO:0007417) 1008 63 8.42 + 7.48 2.04E-38 7.07E-36 generation of neurons (GO:0048699) 1171 65 9.78 + 6.65 1.29E-36 4.36E-34 neuron differentiation (GO:0030182) 1095 63 9.15 + 6.89 2.74E-36 8.87E-34 embryonic skeletal system morphogenesis (GO:0048704) 94 28 0.79 + 35.66 2.70E-36 8.94E-34 tissue development (GO:0009888) 1769 76 14.78 + 5.14 7.02E-36 2.23E-33 positive regulation of nitrogen compound metabolic process (GO:0051173) 2998 95 25.04 + 3.79 1.09E-35 3.38E-33 embryo development ending in birth or egg hatching (GO:0009792) 685 52 5.72 + 9.09 2.01E-35 6.12E-33 chordate embryonic development (GO:0043009) 664 51 5.55 + 9.2 5.87E-35 1.76E-32 neurogenesis (GO:0022008) 1346 67 11.24 + 5.96 6.14E-35 1.80E-32 head development (GO:0060322) 792 54 6.62 + 8.16 1.86E-34 5.35E-32 gland development (GO:0048732) 430 43 3.59 + 11.97 4.30E-34 1.21E-31 skeletal system morphogenesis (GO:0048705) 232 35 1.94 + 18.06 5.11E-34 1.42E-31 positive regulation of cellular metabolic process (GO:0031325) 3341 97 27.91 + 3.48 1.86E-33 5.07E-31 positive regulation of macromolecule metabolic process (GO:0010604) 3413 97 28.51 + 3.4 1.11E-32 2.98E-30 brain development (GO:0007420) 742 50 6.2 + 8.07 1.57E-31 4.13E-29 regulation of cellular process (GO:0050794) 11167 162 93.28 + 1.74 1.71E-31 4.41E-29 regulation of biological process (GO:0050789) 11722 164 97.91 + 1.67 1.68E-30 4.26E-28 positive regulation of metabolic process (GO:0009893) 3719 97 31.06 + 3.12 1.36E-29 3.41E-27 negative regulation of DNA-templated transcription (GO:0045892) 1279 60 10.68 + 5.62 1.58E-29 3.89E-27 negative regulation of RNA biosynthetic process (GO:1902679) 1294 60 10.81 + 5.55 2.97E-29 7.19E-27 positive regulation of cellular process (GO:0048522) 5707 118 47.67 + 2.48 5.56E-29 1.32E-26 sensory organ development (GO:0007423) 599 43 5 + 8.59 4.32E-28 1.01E-25 biological regulation (GO:0065007) 12141 164 101.41 + 1.62 4.39E-28 1.01E-25 negative regulation of RNA metabolic process (GO:0051253) 1410 60 11.78 + 5.09 2.96E-27 6.75E-25 neuron fate commitment (GO:0048663) 72 21 0.6 + 34.92 3.49E-27 7.81E-25 epithelium development (GO:0060429) 1111 54 9.28 + 5.82 4.21E-27 9.29E-25 forebrain development (GO:0030900) 413 36 3.45 + 10.44 2.20E-26 4.78E-24 positive regulation of biological process (GO:0048518) 6210 119 51.87 + 2.29 4.12E-26 8.85E-24 negative regulation of nucleobase-containing compound metabolic process (GO:0045934) 1534 60 12.81 + 4.68 2.53E-25 5.36E-23 negative regulation of transcription by RNA polymerase II (GO:0000122) 940 48 7.85 + 6.11 7.23E-25 1.51E-22 regulation of developmental process (GO:0050793) 2448 71 20.45 + 3.47 1.10E-22 2.26E-20 regulation of cell population proliferation (GO:0042127) 1676 59 14 + 4.21 1.55E-22 3.15E-20 regulation of cell differentiation (GO:0045595) 1566 57 13.08 + 4.36 2.06E-22 4.14E-20 cell development (GO:0048468) 2240 67 18.71 + 3.58 5.85E-22 1.16E-19 cell fate specification (GO:0001708) 88 19 0.74 + 25.85 6.42E-22 1.25E-19 forebrain regionalization (GO:0021871) 24 13 0.2 + 64.85 1.40E-21 2.70E-19 appendage development (GO:0048736) 191 24 1.6 + 15.04 1.55E-21 2.93E-19 limb development (GO:0060173) 191 24 1.6 + 15.04 1.55E-21 2.96E-19 endocrine system development (GO:0035270) 132 21 1.1 + 19.05 3.67E-21 6.82E-19 appendage morphogenesis (GO:0035107) 154 22 1.29 + 17.1 4.62E-21 8.38E-19 limb morphogenesis (GO:0035108) 154 22 1.29 + 17.1 4.62E-21 8.48E-19 negative regulation of macromolecule biosynthetic process (GO:0010558) 2061 63 17.22 + 3.66 5.62E-21 1.01E-18 central nervous system neuron differentiation (GO:0021953) 179 23 1.5 + 15.38 6.72E-21 1.19E-18 sensory organ morphogenesis (GO:0090596) 284 27 2.37 + 11.38 6.99E-21 1.22E-18 tissue morphogenesis (GO:0048729) 574 35 4.79 + 7.3 1.63E-20 2.82E-18 negative regulation of cellular biosynthetic process (GO:0031327) 2113 63 17.65 + 3.57 2.05E-20 3.50E-18 negative regulation of biosynthetic process (GO:0009890) 2127 63 17.77 + 3.55 2.88E-20 4.87E-18 positive regulation of developmental process (GO:0051094) 1337 50 11.17 + 4.48 5.41E-20 9.07E-18 tube morphogenesis (GO:0035239) 684 37 5.71 + 6.48 6.40E-20 1.06E-17 ear morphogenesis (GO:0042471) 133 20 1.11 + 18 1.08E-19 1.77E-17 cell fate determination (GO:0001709) 42 14 0.35 + 39.91 2.03E-19 3.29E-17 anatomical structure formation involved in morphogenesis (GO:0048646) 971 42 8.11 + 5.18 5.41E-19 8.68E-17 negative regulation of nitrogen compound metabolic process (GO:0051172) 2188 62 18.28 + 3.39 6.11E-19 9.70E-17 embryonic appendage morphogenesis (GO:0035113) 125 19 1.04 + 18.2 7.48E-19 1.16E-16 embryonic limb morphogenesis (GO:0030326) 125 19 1.04 + 18.2 7.48E-19 1.18E-16 tube development (GO:0035295) 905 40 7.56 + 5.29 2.07E-18 3.19E-16 regulation of multicellular organismal development (GO:2000026) 1404 49 11.73 + 4.18 2.48E-18 3.78E-16 cell population proliferation (GO:0008283) 732 36 6.11 + 5.89 4.75E-18 7.17E-16 telencephalon development (GO:0021537) 278 24 2.32 + 10.34 1.13E-17 1.68E-15 negative regulation of cellular metabolic process (GO:0031324) 2572 65 21.48 + 3.03 2.15E-17 3.18E-15 morphogenesis of an epithelium (GO:0002009) 463 29 3.87 + 7.5 2.18E-17 3.20E-15 negative regulation of cellular process (GO:0048523) 4848 92 40.49 + 2.27 2.79E-17 4.06E-15 negative regulation of metabolic process (GO:0009892) 2828 68 23.62 + 2.88 3.64E-17 5.24E-15 epithelial cell differentiation (GO:0030855) 643 33 5.37 + 6.14 4.06E-17 5.78E-15 negative regulation of neuron differentiation (GO:0045665) 74 15 0.62 + 24.27 4.30E-17 6.07E-15 negative regulation of macromolecule metabolic process (GO:0010605) 2609 65 21.79 + 2.98 4.43E-17 6.20E-15 proximal/distal pattern formation (GO:0009954) 35 12 0.29 + 41.05 5.52E-17 7.66E-15 stem cell differentiation (GO:0048863) 182 20 1.52 + 13.16 6.14E-17 8.44E-15 negative regulation of cell differentiation (GO:0045596) 670 33 5.6 + 5.9 1.36E-16 1.85E-14 negative regulation of developmental process (GO:0051093) 919 38 7.68 + 4.95 1.55E-16 2.09E-14 neuron development (GO:0048666) 869 37 7.26 + 5.1 1.64E-16 2.19E-14 neuron migration (GO:0001764) 142 18 1.19 + 15.18 1.81E-16 2.40E-14 axon development (GO:0061564) 423 27 3.53 + 7.64 1.93E-16 2.53E-14 regulation of neuron differentiation (GO:0045664) 194 20 1.62 + 12.34 2.17E-16 2.83E-14 negative regulation of biological process (GO:0048519) 5208 94 43.5 + 2.16 2.41E-16 3.11E-14 inner ear morphogenesis (GO:0042472) 112 16 0.94 + 17.1 1.31E-15 1.68E-13 epithelial tube morphogenesis (GO:0060562) 317 23 2.65 + 8.69 2.52E-15 3.20E-13 muscle structure development (GO:0061061) 517 28 4.32 + 6.48 3.35E-15 4.22E-13 regulation of multicellular organismal process (GO:0051239) 2966 66 24.77 + 2.66 6.63E-15 8.28E-13 positive regulation of cell differentiation (GO:0045597) 871 35 7.28 + 4.81 7.01E-15 8.69E-13 ear development (GO:0043583) 233 20 1.95 + 10.28 7.64E-15 9.39E-13 morphogenesis of a branching structure (GO:0001763) 177 18 1.48 + 12.18 9.38E-15 1.14E-12 mesenchyme development (GO:0060485) 246 20 2.05 + 9.73 2.16E-14 2.61E-12 telencephalon regionalization (GO:0021978) 13 8 0.11 + 73.67 2.50E-14 3.00E-12 branching morphogenesis of an epithelial tube (GO:0048754) 137 16 1.14 + 13.98 3.42E-14 4.07E-12 morphogenesis of a branching epithelium (GO:0061138) 166 17 1.39 + 12.26 4.77E-14 5.64E-12 axonogenesis (GO:0007409) 370 23 3.09 + 7.44 6.85E-14 8.03E-12 positive regulation of cell population proliferation (GO:0008284) 950 35 7.94 + 4.41 9.11E-14 1.06E-11 muscle tissue development (GO:0060537) 344 22 2.87 + 7.66 1.40E-13 1.61E-11 neuron fate specification (GO:0048665) 34 10 0.28 + 35.21 1.40E-13 1.62E-11 neuron projection development (GO:0031175) 702 30 5.86 + 5.12 1.61E-13 1.83E-11 dorsal/ventral pattern formation (GO:0009953) 85 13 0.71 + 18.31 2.67E-13 3.02E-11 sensory system development (GO:0048880) 399 23 3.33 + 6.9 3.34E-13 3.74E-11 pallium development (GO:0021543) 194 17 1.62 + 10.49 6.27E-13 6.97E-11 neuron projection guidance (GO:0097485) 228 18 1.9 + 9.45 7.63E-13 8.37E-11 axon guidance (GO:0007411) 228 18 1.9 + 9.45 7.63E-13 8.43E-11 camera-type eye development (GO:0043010) 341 21 2.85 + 7.37 1.08E-12 1.18E-10 forelimb morphogenesis (GO:0035136) 41 10 0.34 + 29.2 1.14E-12 1.23E-10 GABAergic neuron differentiation (GO:0097154) 19 8 0.16 + 50.41 1.41E-12 1.51E-10 inner ear development (GO:0048839) 206 17 1.72 + 9.88 1.67E-12 1.76E-10 eye development (GO:0001654) 389 22 3.25 + 6.77 1.66E-12 1.76E-10 outflow tract morphogenesis (GO:0003151) 77 12 0.64 + 18.66 1.80E-12 1.89E-10 visual system development (GO:0150063) 393 22 3.28 + 6.7 2.03E-12 2.12E-10 muscle organ development (GO:0007517) 315 20 2.63 + 7.6 2.22E-12 2.30E-10 regulation of cell development (GO:0060284) 836 31 6.98 + 4.44 2.49E-12 2.57E-10 cell migration (GO:0016477) 901 32 7.53 + 4.25 3.28E-12 3.36E-10 diencephalon development (GO:0021536) 81 12 0.68 + 17.74 3.36E-12 3.39E-10 neuron projection morphogenesis (GO:0048812) 491 24 4.1 + 5.85 3.36E-12 3.42E-10 cranial nerve morphogenesis (GO:0021602) 32 9 0.27 + 33.67 3.81E-12 3.80E-10 cell morphogenesis involved in neuron differentiation (GO:0048667) 449 23 3.75 + 6.13 3.81E-12 3.82E-10 plasma membrane bounded cell projection morphogenesis (GO:0120039) 496 24 4.14 + 5.79 4.16E-12 4.12E-10 cell projection morphogenesis (GO:0048858) 501 24 4.18 + 5.74 5.14E-12 5.06E-10 cranial nerve development (GO:0021545) 65 11 0.54 + 20.26 6.06E-12 5.92E-10 circulatory system development (GO:0072359) 928 32 7.75 + 4.13 7.14E-12 6.93E-10 cellular anatomical entity morphogenesis (GO:0032989) 612 26 5.11 + 5.09 9.15E-12 8.83E-10 cell differentiation in spinal cord (GO:0021515) 50 10 0.42 + 23.94 9.78E-12 9.38E-10 regulation of neurogenesis (GO:0050767) 389 21 3.25 + 6.46 1.32E-11 1.25E-09 organonitrogen compound metabolic process (GO:1901564) 4671 7 39.02 - 0.18 1.32E-11 1.26E-09 regulation of animal organ morphogenesis (GO:2000027) 93 12 0.78 + 15.45 1.82E-11 1.71E-09 spinal cord development (GO:0021510) 98 12 0.82 + 14.66 3.42E-11 3.19E-09 hematopoietic or lymphoid organ development (GO:0048534) 100 12 0.84 + 14.37 4.35E-11 4.05E-09 limbic system development (GO:0021761) 126 13 1.05 + 12.35 4.60E-11 4.25E-09 regulation of nervous system development (GO:0051960) 464 22 3.88 + 5.68 5.20E-11 4.77E-09 forebrain neuron differentiation (GO:0021879) 42 9 0.35 + 25.65 5.64E-11 5.15E-09 heart morphogenesis (GO:0003007) 259 17 2.16 + 7.86 6.43E-11 5.84E-09 cell motility (GO:0048870) 1081 33 9.03 + 3.65 8.07E-11 7.28E-09 ventral spinal cord development (GO:0021517) 45 9 0.38 + 23.94 1.10E-10 9.84E-09 thyroid gland development (GO:0030878) 31 8 0.26 + 30.9 1.35E-10 1.20E-08 autonomic nervous system development (GO:0048483) 46 9 0.38 + 23.42 1.36E-10 1.20E-08 cell morphogenesis (GO:0000902) 696 26 5.81 + 4.47 1.54E-10 1.35E-08 positive regulation of multicellular organismal process (GO:0051240) 1652 41 13.8 + 2.97 1.69E-10 1.48E-08 renal system development (GO:0072001) 317 18 2.65 + 6.8 1.85E-10 1.61E-08 mesenchymal cell differentiation (GO:0048762) 172 14 1.44 + 9.74 1.99E-10 1.72E-08 embryonic forelimb morphogenesis (GO:0035115) 33 8 0.28 + 29.02 2.34E-10 2.01E-08 roof of mouth development (GO:0060021) 92 11 0.77 + 14.31 3.00E-10 2.57E-08 mesonephros development (GO:0001823) 94 11 0.79 + 14.01 3.80E-10 3.23E-08 olfactory bulb development (GO:0021772) 35 8 0.29 + 27.36 3.91E-10 3.31E-08 plasma membrane bounded cell projection organization (GO:0120036) 1156 33 9.66 + 3.42 4.55E-10 3.83E-08 hindlimb morphogenesis (GO:0035137) 36 8 0.3 + 26.6 4.99E-10 4.18E-08 cranial skeletal system development (GO:1904888) 73 10 0.61 + 16.4 5.02E-10 4.18E-08 odontogenesis (GO:0042476) 124 12 1.04 + 11.59 5.55E-10 4.60E-08 nerve development (GO:0021675) 98 11 0.82 + 13.44 5.98E-10 4.93E-08 forebrain generation of neurons (GO:0021872) 54 9 0.45 + 19.95 6.18E-10 5.06E-08 olfactory lobe development (GO:0021988) 37 8 0.31 + 25.89 6.32E-10 5.15E-08 protein metabolic process (GO:0019538) 3548 4 29.64 - 0.13 7.79E-10 6.32E-08 forebrain neuron fate commitment (GO:0021877) 7 5 0.06 + 85.51 7.95E-10 6.38E-08 cerebral cortex regionalization (GO:0021796) 7 5 0.06 + 85.51 7.95E-10 6.41E-08 mammary gland development (GO:0030879) 128 12 1.07 + 11.22 8.04E-10 6.42E-08 cerebral cortex development (GO:0021987) 130 12 1.09 + 11.05 9.63E-10 7.64E-08 hindbrain development (GO:0030902) 161 13 1.34 + 9.67 9.97E-10 7.88E-08 ureteric bud morphogenesis (GO:0060675) 57 9 0.48 + 18.9 1.02E-09 8.04E-08 mesonephric tubule morphogenesis (GO:0072171) 58 9 0.48 + 18.58 1.20E-09 9.40E-08 mesoderm development (GO:0007498) 133 12 1.11 + 10.8 1.25E-09 9.75E-08 cell projection organization (GO:0030030) 1205 33 10.07 + 3.28 1.30E-09 1.01E-07 neural precursor cell proliferation (GO:0061351) 106 11 0.89 + 12.42 1.40E-09 1.08E-07 peripheral nervous system neuron differentiation (GO:0048934) 15 6 0.13 + 47.89 1.46E-09 1.11E-07 cerebral cortex neuron differentiation (GO:0021895) 26 7 0.22 + 32.23 1.44E-09 1.11E-07 peripheral nervous system neuron development (GO:0048935) 15 6 0.13 + 47.89 1.46E-09 1.12E-07 gliogenesis (GO:0042063) 277 16 2.31 + 6.92 1.56E-09 1.18E-07 embryonic digit morphogenesis (GO:0042733) 61 9 0.51 + 17.66 1.92E-09 1.44E-07 regulation of anatomical structure morphogenesis (GO:0022603) 845 27 7.06 + 3.83 2.02E-09 1.51E-07 nephron epithelium development (GO:0072009) 110 11 0.92 + 11.97 2.09E-09 1.55E-07 rhombomere development (GO:0021546) 8 5 0.07 + 74.83 2.10E-09 1.56E-07 heart development (GO:0007507) 566 22 4.73 + 4.65 2.19E-09 1.61E-07 pituitary gland development (GO:0021983) 43 8 0.36 + 22.27 2.27E-09 1.67E-07 nephron tubule development (GO:0072080) 86 10 0.72 + 13.92 2.60E-09 1.90E-07 embryonic cranial skeleton morphogenesis (GO:0048701) 45 8 0.38 + 21.28 3.33E-09 2.42E-07 ureter development (GO:0072189) 17 6 0.14 + 42.25 3.57E-09 2.58E-07 ureteric bud development (GO:0001657) 89 10 0.74 + 13.45 3.66E-09 2.63E-07 branching involved in ureteric bud morphogenesis (GO:0001658) 46 8 0.38 + 20.82 4.01E-09 2.87E-07 mesonephric epithelium development (GO:0072163) 90 10 0.75 + 13.3 4.09E-09 2.90E-07 mesonephric tubule development (GO:0072164) 90 10 0.75 + 13.3 4.09E-09 2.91E-07 pharyngeal system development (GO:0060037) 30 7 0.25 + 27.93 4.35E-09 3.07E-07 renal tubule development (GO:0061326) 91 10 0.76 + 13.16 4.56E-09 3.20E-07 interneuron axon guidance (GO:0097376) 4 4 0.03 + > 100 4.70E-09 3.29E-07 DNA-templated transcription (GO:0006351) 539 21 4.5 + 4.66 5.01E-09 3.47E-07 response to endogenous stimulus (GO:0009719) 1411 35 11.79 + 2.97 4.99E-09 3.47E-07 positive regulation of neuron differentiation (GO:0045666) 93 10 0.78 + 12.87 5.65E-09 3.90E-07 nephron tubule morphogenesis (GO:0072078) 69 9 0.58 + 15.62 5.91E-09 4.06E-07 kidney development (GO:0001822) 307 16 2.56 + 6.24 6.80E-09 4.65E-07 RNA biosynthetic process (GO:0032774) 551 21 4.6 + 4.56 7.36E-09 5.01E-07 nephron epithelium morphogenesis (GO:0072088) 71 9 0.59 + 15.18 7.66E-09 5.19E-07 Unclassified (UNCLASSIFIED) 2787 2 23.28 - 0.09 8.04E-09 5.40E-07 biological_process (GO:0008150) 17805 170 148.72 + 1.14 8.04E-09 5.42E-07 cardiac chamber morphogenesis (GO:0003206) 125 11 1.04 + 10.54 8.16E-09 5.45E-07 cerebral cortex GABAergic interneuron differentiation (GO:0021892) 10 5 0.08 + 59.86 9.34E-09 6.22E-07 renal tubule morphogenesis (GO:0061333) 73 9 0.61 + 14.76 9.85E-09 6.50E-07 nephron morphogenesis (GO:0072028) 73 9 0.61 + 14.76 9.85E-09 6.53E-07 regulation of epithelial cell proliferation (GO:0050678) 361 17 3.02 + 5.64 1.02E-08 6.70E-07 regulation of neural precursor cell proliferation (GO:2000177) 104 10 0.87 + 11.51 1.69E-08 1.10E-06 immune system development (GO:0002520) 167 12 1.39 + 8.6 1.68E-08 1.10E-06 cardiac chamber development (GO:0003205) 169 12 1.41 + 8.5 1.92E-08 1.24E-06 atrial cardiac muscle tissue development (GO:0003228) 22 6 0.18 + 32.65 2.08E-08 1.34E-06 cardiac conduction system development (GO:0003161) 37 7 0.31 + 22.65 2.09E-08 1.35E-06 cellular response to endogenous stimulus (GO:0071495) 1148 30 9.59 + 3.13 2.38E-08 1.53E-06 cardiac septum development (GO:0003279) 108 10 0.9 + 11.09 2.43E-08 1.55E-06 columnar/cuboidal epithelial cell differentiation (GO:0002065) 109 10 0.91 + 10.98 2.66E-08 1.69E-06 nephron development (GO:0072006) 140 11 1.17 + 9.41 2.68E-08 1.69E-06 response to retinoic acid (GO:0032526) 110 10 0.92 + 10.88 2.90E-08 1.83E-06 kidney epithelium development (GO:0072073) 142 11 1.19 + 9.27 3.10E-08 1.95E-06 cartilage development (GO:0051216) 178 12 1.49 + 8.07 3.42E-08 2.14E-06 outflow tract septum morphogenesis (GO:0003148) 24 6 0.2 + 29.93 3.70E-08 2.30E-06 glial cell differentiation (GO:0010001) 218 13 1.82 + 7.14 3.88E-08 2.41E-06 mammary gland epithelium development (GO:0061180) 61 8 0.51 + 15.7 4.07E-08 2.51E-06 metanephros development (GO:0001656) 86 9 0.72 + 12.53 4.25E-08 2.61E-06 response to growth factor (GO:0070848) 506 19 4.23 + 4.5 5.08E-08 3.11E-06 kidney morphogenesis (GO:0060993) 90 9 0.75 + 11.97 6.35E-08 3.87E-06 commitment of neuronal cell to specific neuron type in forebrain (GO:0021902) 6 4 0.05 + 79.81 6.96E-08 4.23E-06 interneuron migration (GO:1904936) 14 5 0.12 + 42.76 7.23E-08 4.37E-06 connective tissue development (GO:0061448) 236 13 1.97 + 6.59 9.85E-08 5.93E-06 cell fate commitment involved in formation of primary germ layer (GO:0060795) 28 6 0.23 + 25.65 1.01E-07 6.04E-06 cellular response to growth factor stimulus (GO:0071363) 475 18 3.97 + 4.54 1.02E-07 6.09E-06 blood vessel development (GO:0001568) 530 19 4.43 + 4.29 1.05E-07 6.24E-06 negative regulation of apoptotic process (GO:0043066) 894 25 7.47 + 3.35 1.15E-07 6.79E-06 sex differentiation (GO:0007548) 283 14 2.36 + 5.92 1.18E-07 6.99E-06 cardiac septum morphogenesis (GO:0060411) 70 8 0.58 + 13.68 1.22E-07 7.20E-06 bone development (GO:0060348) 201 12 1.68 + 7.15 1.30E-07 7.63E-06 regulation of neuron apoptotic process (GO:0043523) 243 13 2.03 + 6.4 1.38E-07 8.07E-06 axis specification (GO:0009798) 99 9 0.83 + 10.88 1.46E-07 8.49E-06 spinal cord motor neuron differentiation (GO:0021522) 30 6 0.25 + 23.94 1.56E-07 9.07E-06 positive regulation of neurogenesis (GO:0050769) 246 13 2.05 + 6.33 1.59E-07 9.20E-06 forebrain dorsal/ventral pattern formation (GO:0021798) 7 4 0.06 + 68.41 1.61E-07 9.28E-06 segmentation (GO:0035282) 101 9 0.84 + 10.67 1.73E-07 9.94E-06 response to lipid (GO:0033993) 852 24 7.12 + 3.37 1.85E-07 1.06E-05 positive regulation of nervous system development (GO:0051962) 294 14 2.46 + 5.7 1.89E-07 1.07E-05 mesoderm morphogenesis (GO:0048332) 74 8 0.62 + 12.94 1.90E-07 1.08E-05 vasculature development (GO:0001944) 551 19 4.6 + 4.13 1.91E-07 1.08E-05 negative regulation of programmed cell death (GO:0043069) 921 25 7.69 + 3.25 2.01E-07 1.13E-05 positive regulation of cell development (GO:0010720) 453 17 3.78 + 4.49 2.70E-07 1.51E-05 neuroblast differentiation (GO:0014016) 8 4 0.07 + 59.86 3.21E-07 1.78E-05 parathyroid gland development (GO:0060017) 8 4 0.07 + 59.86 3.21E-07 1.79E-05 skeletal muscle tissue development (GO:0007519) 144 10 1.2 + 8.31 3.73E-07 2.06E-05 mesenchyme morphogenesis (GO:0072132) 56 7 0.47 + 14.97 4.12E-07 2.28E-05 oligodendrocyte differentiation (GO:0048709) 82 8 0.68 + 11.68 4.24E-07 2.33E-05 dopaminergic neuron differentiation (GO:0071542) 36 6 0.3 + 19.95 4.92E-07 2.70E-05 dorsal spinal cord development (GO:0021516) 20 5 0.17 + 29.93 5.37E-07 2.94E-05 protein modification process (GO:0036211) 2069 1 17.28 - 0.06 5.56E-07 3.03E-05 odontogenesis of dentin-containing tooth (GO:0042475) 85 8 0.71 + 11.27 5.61E-07 3.04E-05 spinal cord interneuron axon guidance (GO:0097377) 3 3 0.03 + > 100 5.73E-07 3.07E-05 cardiac muscle tissue development (GO:0048738) 189 11 1.58 + 6.97 5.69E-07 3.07E-05 forebrain anterior/posterior pattern specification (GO:0021797) 3 3 0.03 + > 100 5.73E-07 3.08E-05 Notch signaling pathway (GO:0007219) 117 9 0.98 + 9.21 6.12E-07 3.27E-05 spleen development (GO:0048536) 38 6 0.32 + 18.9 6.88E-07 3.67E-05 middle ear morphogenesis (GO:0042474) 21 5 0.18 + 28.5 7.00E-07 3.72E-05 blood vessel morphogenesis (GO:0048514) 431 16 3.6 + 4.44 7.12E-07 3.77E-05 developmental growth (GO:0048589) 432 16 3.61 + 4.43 7.34E-07 3.86E-05 growth (GO:0040007) 432 16 3.61 + 4.43 7.34E-07 3.87E-05 striated muscle tissue development (GO:0014706) 195 11 1.63 + 6.75 7.75E-07 4.06E-05 skeletal muscle organ development (GO:0060538) 156 10 1.3 + 7.67 7.80E-07 4.07E-05 peripheral nervous system development (GO:0007422) 90 8 0.75 + 10.64 8.71E-07 4.53E-05 formation of primary germ layer (GO:0001704) 123 9 1.03 + 8.76 9.34E-07 4.84E-05 lung secretory cell differentiation (GO:0061140) 10 4 0.08 + 47.89 9.49E-07 4.86E-05 neuron fate determination (GO:0048664) 10 4 0.08 + 47.89 9.49E-07 4.87E-05 embryonic viscerocranium morphogenesis (GO:0048703) 10 4 0.08 + 47.89 9.49E-07 4.89E-05 neural crest cell differentiation (GO:0014033) 91 8 0.76 + 10.52 9.49E-07 4.90E-05 positive regulation of neural precursor cell proliferation (GO:2000179) 64 7 0.53 + 13.09 1.04E-06 5.31E-05 urogenital system development (GO:0001655) 64 7 0.53 + 13.09 1.04E-06 5.32E-05 negative regulation of neuron apoptotic process (GO:0043524) 162 10 1.35 + 7.39 1.10E-06 5.58E-05 regulation of morphogenesis of an epithelium (GO:1905330) 65 7 0.54 + 12.89 1.16E-06 5.87E-05 positive regulation of epithelial cell proliferation (GO:0050679) 204 11 1.7 + 6.46 1.21E-06 6.08E-05 hippocampus development (GO:0021766) 95 8 0.79 + 10.08 1.32E-06 6.61E-05 transcription by RNA polymerase II (GO:0006366) 400 15 3.34 + 4.49 1.42E-06 7.10E-05 spinal cord motor neuron cell fate specification (GO:0021520) 11 4 0.09 + 43.53 1.48E-06 7.38E-05 reproductive structure development (GO:0048608) 302 13 2.52 + 5.15 1.63E-06 8.08E-05 male sex differentiation (GO:0046661) 170 10 1.42 + 7.04 1.71E-06 8.46E-05 digestive tract development (GO:0048565) 133 9 1.11 + 8.1 1.80E-06 8.88E-05 reproductive system development (GO:0061458) 306 13 2.56 + 5.09 1.88E-06 9.25E-05 gastrulation (GO:0007369) 172 10 1.44 + 6.96 1.90E-06 9.31E-05 camera-type eye morphogenesis (GO:0048593) 134 9 1.12 + 8.04 1.92E-06 9.36E-05 pancreas development (GO:0031016) 70 7 0.58 + 11.97 1.93E-06 9.41E-05 respiratory system development (GO:0060541) 216 11 1.8 + 6.1 2.11E-06 1.03E-04 sinoatrial node development (GO:0003163) 12 4 0.1 + 39.91 2.21E-06 1.06E-04 embryonic camera-type eye morphogenesis (GO:0048596) 26 5 0.22 + 23.02 2.19E-06 1.06E-04 spinal cord association neuron differentiation (GO:0021527) 12 4 0.1 + 39.91 2.21E-06 1.07E-04 oligodendrocyte cell fate specification (GO:0021778) 4 3 0.03 + 89.79 2.28E-06 1.08E-04 glossopharyngeal nerve morphogenesis (GO:0021615) 4 3 0.03 + 89.79 2.28E-06 1.08E-04 central nervous system segmentation (GO:0035283) 4 3 0.03 + 89.79 2.28E-06 1.08E-04 oligodendrocyte cell fate commitment (GO:0021779) 4 3 0.03 + 89.79 2.28E-06 1.09E-04 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090092) 263 12 2.2 + 5.46 2.27E-06 1.09E-04 mesoderm formation (GO:0001707) 72 7 0.6 + 11.64 2.34E-06 1.11E-04 bone morphogenesis (GO:0060349) 103 8 0.86 + 9.3 2.44E-06 1.15E-04 stem cell proliferation (GO:0072089) 73 7 0.61 + 11.48 2.57E-06 1.21E-04 uterus development (GO:0060065) 27 5 0.23 + 22.17 2.67E-06 1.25E-04 regulation of BMP signaling pathway (GO:0030510) 105 8 0.88 + 9.12 2.82E-06 1.31E-04 regulation of cellular response to growth factor stimulus (GO:0090287) 319 13 2.66 + 4.88 2.97E-06 1.38E-04 canonical Wnt signaling pathway (GO:0060070) 106 8 0.89 + 9.04 3.03E-06 1.40E-04 embryonic hindlimb morphogenesis (GO:0035116) 28 5 0.23 + 21.38 3.23E-06 1.48E-04 subpallium development (GO:0021544) 28 5 0.23 + 21.38 3.23E-06 1.49E-04 mesodermal cell differentiation (GO:0048333) 28 5 0.23 + 21.38 3.23E-06 1.49E-04 gland morphogenesis (GO:0022612) 107 8 0.89 + 8.95 3.25E-06 1.49E-04 regulation of developmental growth (GO:0048638) 324 13 2.71 + 4.8 3.53E-06 1.61E-04 thymus development (GO:0048538) 50 6 0.42 + 14.37 3.65E-06 1.66E-04 digestive system development (GO:0055123) 145 9 1.21 + 7.43 3.68E-06 1.67E-04 endocardial cushion development (GO:0003197) 51 6 0.43 + 14.08 4.10E-06 1.86E-04 nitrogen compound metabolic process (GO:0006807) 6426 27 53.67 - 0.5 4.35E-06 1.96E-04 macromolecule modification (GO:0043412) 2291 3 19.14 - 0.16 4.42E-06 1.97E-04 regulation of mesenchymal cell apoptotic process (GO:2001053) 14 4 0.12 + 34.21 4.41E-06 1.98E-04 mesodermal cell fate commitment (GO:0001710) 14 4 0.12 + 34.21 4.41E-06 1.98E-04 muscle cell differentiation (GO:0042692) 283 12 2.36 + 5.08 4.83E-06 2.15E-04 regulation of neuroblast proliferation (GO:1902692) 53 6 0.44 + 13.55 5.16E-06 2.29E-04 face development (GO:0060324) 53 6 0.44 + 13.55 5.16E-06 2.29E-04 glossopharyngeal nerve development (GO:0021563) 5 3 0.04 + 71.83 5.66E-06 2.50E-04 endoderm development (GO:0007492) 84 7 0.7 + 9.98 6.62E-06 2.92E-04 neuroblast proliferation (GO:0007405) 56 6 0.47 + 12.83 7.15E-06 3.14E-04 embryonic heart tube development (GO:0035050) 85 7 0.71 + 9.86 7.16E-06 3.14E-04 neuroepithelial cell differentiation (GO:0060563) 33 5 0.28 + 18.14 7.53E-06 3.28E-04 regulation of neuron projection development (GO:0010975) 459 15 3.83 + 3.91 7.56E-06 3.28E-04 developmental induction (GO:0031128) 33 5 0.28 + 18.14 7.53E-06 3.29E-04 cardiocyte differentiation (GO:0035051) 120 8 1 + 7.98 7.64E-06 3.31E-04 muscle cell fate commitment (GO:0042693) 16 4 0.13 + 29.93 7.91E-06 3.41E-04 nose development (GO:0043584) 16 4 0.13 + 29.93 7.91E-06 3.42E-04 negative regulation of cell population proliferation (GO:0008285) 710 19 5.93 + 3.2 8.08E-06 3.47E-04 retina development in camera-type eye (GO:0060041) 160 9 1.34 + 6.73 8.22E-06 3.52E-04 eye morphogenesis (GO:0048592) 162 9 1.35 + 6.65 9.09E-06 3.88E-04 cellular response to lipid (GO:0071396) 528 16 4.41 + 3.63 9.59E-06 4.08E-04 embryonic eye morphogenesis (GO:0048048) 35 5 0.29 + 17.1 1.02E-05 4.30E-04 regulation of kidney development (GO:0090183) 35 5 0.29 + 17.1 1.02E-05 4.32E-04 regulation of mammary gland epithelial cell proliferation (GO:0033599) 17 4 0.14 + 28.17 1.03E-05 4.33E-04 preganglionic parasympathetic fiber development (GO:0021783) 17 4 0.14 + 28.17 1.03E-05 4.34E-04 regulation of amacrine cell differentiation (GO:1902869) 6 3 0.05 + 59.86 1.12E-05 4.72E-04 system process (GO:0003008) 2108 37 17.61 + 2.1 1.13E-05 4.73E-04 positive regulation of developmental growth (GO:0048639) 167 9 1.39 + 6.45 1.16E-05 4.85E-04 smooth muscle cell differentiation (GO:0051145) 36 5 0.3 + 16.63 1.17E-05 4.87E-04 positive regulation of animal organ morphogenesis (GO:0110110) 36 5 0.3 + 16.63 1.17E-05 4.88E-04 embryonic camera-type eye development (GO:0031076) 37 5 0.31 + 16.18 1.35E-05 5.56E-04 positive regulation of morphogenesis of an epithelium (GO:1905332) 37 5 0.31 + 16.18 1.35E-05 5.58E-04 response to oxygen-containing compound (GO:1901700) 1554 30 12.98 + 2.31 1.46E-05 6.01E-04 response to ketone (GO:1901654) 217 10 1.81 + 5.52 1.49E-05 6.12E-04 forebrain cell migration (GO:0021885) 64 6 0.53 + 11.22 1.56E-05 6.38E-04 glandular epithelial cell differentiation (GO:0002067) 64 6 0.53 + 11.22 1.56E-05 6.40E-04 parasympathetic nervous system development (GO:0048486) 19 4 0.16 + 25.2 1.65E-05 6.66E-04 positive regulation of branching involved in ureteric bud morphogenesis (GO:0090190) 19 4 0.16 + 25.2 1.65E-05 6.68E-04 nephron tubule formation (GO:0072079) 19 4 0.16 + 25.2 1.65E-05 6.70E-04 definitive hemopoiesis (GO:0060216) 19 4 0.16 + 25.2 1.65E-05 6.71E-04 catabolic process (GO:0009056) 1938 2 16.19 - 0.12 1.65E-05 6.73E-04 ureter morphogenesis (GO:0072197) 7 3 0.06 + 51.31 1.96E-05 7.82E-04 anterior/posterior axon guidance (GO:0033564) 7 3 0.06 + 51.31 1.96E-05 7.84E-04 glial cell fate specification (GO:0021780) 7 3 0.06 + 51.31 1.96E-05 7.87E-04 endocardial cushion morphogenesis (GO:0003203) 40 5 0.33 + 14.97 1.99E-05 7.93E-04 animal organ formation (GO:0048645) 40 5 0.33 + 14.97 1.99E-05 7.95E-04 determination of left/right symmetry (GO:0007368) 137 8 1.14 + 6.99 2.02E-05 8.00E-04 artery development (GO:0060840) 100 7 0.84 + 8.38 2.09E-05 8.28E-04 gonad development (GO:0008406) 227 10 1.9 + 5.27 2.19E-05 8.67E-04 artery morphogenesis (GO:0048844) 68 6 0.57 + 10.56 2.22E-05 8.74E-04 retinal ganglion cell axon guidance (GO:0031290) 21 4 0.18 + 22.8 2.52E-05 9.87E-04 tongue development (GO:0043586) 21 4 0.18 + 22.8 2.52E-05 9.89E-04 cellular response to retinoic acid (GO:0071300) 70 6 0.58 + 10.26 2.62E-05 1.02E-03 development of primary sexual characteristics (GO:0045137) 232 10 1.94 + 5.16 2.65E-05 1.03E-03 left/right pattern formation (GO:0060972) 143 8 1.19 + 6.7 2.75E-05 1.06E-03 determination of bilateral symmetry (GO:0009855) 143 8 1.19 + 6.7 2.75E-05 1.07E-03 specification of symmetry (GO:0009799) 143 8 1.19 + 6.7 2.75E-05 1.07E-03 regulation of branching involved in ureteric bud morphogenesis (GO:0090189) 22 4 0.18 + 21.77 3.06E-05 1.18E-03 male gonad development (GO:0008584) 147 8 1.23 + 6.52 3.35E-05 1.29E-03 development of primary male sexual characteristics (GO:0046546) 148 8 1.24 + 6.47 3.51E-05 1.35E-03 body morphogenesis (GO:0010171) 45 5 0.38 + 13.3 3.58E-05 1.37E-03 cellular response to prostaglandin stimulus (GO:0071379) 23 4 0.19 + 20.82 3.68E-05 1.40E-03 nucleobase-containing compound biosynthetic process (GO:0034654) 938 21 7.83 + 2.68 3.83E-05 1.46E-03 embryonic pattern specification (GO:0009880) 76 6 0.63 + 9.45 4.19E-05 1.59E-03 neuromuscular process (GO:0050905) 153 8 1.28 + 6.26 4.45E-05 1.69E-03 cardiac pacemaker cell development (GO:0060926) 9 3 0.08 + 39.91 4.64E-05 1.75E-03 neural crest cell development (GO:0014032) 78 6 0.65 + 9.21 4.86E-05 1.83E-03 positive regulation of stem cell proliferation (GO:2000648) 48 5 0.4 + 12.47 4.91E-05 1.85E-03 endocardial cushion formation (GO:0003272) 25 4 0.21 + 19.16 5.18E-05 1.95E-03 alpha-beta T cell differentiation (GO:0046632) 79 6 0.66 + 9.09 5.22E-05 1.96E-03 regulation of epithelial cell differentiation (GO:0030856) 157 8 1.31 + 6.1 5.35E-05 2.00E-03 digestive tract morphogenesis (GO:0048546) 49 5 0.41 + 12.22 5.43E-05 2.02E-03 negative regulation of multicellular organismal process (GO:0051241) 1116 23 9.32 + 2.47 5.75E-05 2.14E-03 lung morphogenesis (GO:0060425) 50 5 0.42 + 11.97 6.00E-05 2.22E-03 lung cell differentiation (GO:0060479) 26 4 0.22 + 18.42 6.09E-05 2.24E-03 cochlea morphogenesis (GO:0090103) 26 4 0.22 + 18.42 6.09E-05 2.24E-03 lung epithelial cell differentiation (GO:0060487) 26 4 0.22 + 18.42 6.09E-05 2.25E-03 metencephalon development (GO:0022037) 118 7 0.99 + 7.1 6.08E-05 2.25E-03 locomotory behavior (GO:0007626) 207 9 1.73 + 5.21 6.30E-05 2.31E-03 pancreatic A cell differentiation (GO:0003310) 10 3 0.08 + 35.92 6.58E-05 2.40E-03 tongue morphogenesis (GO:0043587) 10 3 0.08 + 35.92 6.58E-05 2.41E-03 neurohypophysis development (GO:0021985) 2 2 0.02 + > 100 6.94E-05 2.48E-03 cerebral cortex GABAergic interneuron fate commitment (GO:0021893) 2 2 0.02 + > 100 6.94E-05 2.48E-03 optic vesicle morphogenesis (GO:0003404) 2 2 0.02 + > 100 6.94E-05 2.49E-03 ureter smooth muscle contraction (GO:0014849) 2 2 0.02 + > 100 6.94E-05 2.49E-03 dorsal spinal cord interneuron axon guidance (GO:0097378) 2 2 0.02 + > 100 6.94E-05 2.50E-03 ureteric peristalsis (GO:0072105) 2 2 0.02 + > 100 6.94E-05 2.51E-03 regulation of glutamatergic neuron differentiation (GO:0120006) 2 2 0.02 + > 100 6.94E-05 2.51E-03 regulation of stem cell proliferation (GO:0072091) 83 6 0.69 + 8.65 6.90E-05 2.51E-03 subpallium neuron fate commitment (GO:0060163) 2 2 0.02 + > 100 6.94E-05 2.52E-03 cell proliferation in forebrain (GO:0021846) 27 4 0.23 + 17.74 7.10E-05 2.52E-03 epithelial tube branching involved in lung morphogenesis (GO:0060441) 27 4 0.23 + 17.74 7.10E-05 2.53E-03 stem cell development (GO:0048864) 84 6 0.7 + 8.55 7.38E-05 2.62E-03 hemopoiesis (GO:0030097) 699 17 5.84 + 2.91 8.13E-05 2.88E-03 hypothalamus development (GO:0021854) 28 4 0.23 + 17.1 8.23E-05 2.90E-03 behavior (GO:0007610) 632 16 5.28 + 3.03 8.35E-05 2.94E-03 cellular response to fibroblast growth factor stimulus (GO:0044344) 86 6 0.72 + 8.35 8.42E-05 2.96E-03 lung alveolus development (GO:0048286) 54 5 0.45 + 11.09 8.71E-05 3.05E-03 regulation of morphogenesis of a branching structure (GO:0060688) 54 5 0.45 + 11.09 8.71E-05 3.05E-03 nail development (GO:0035878) 11 3 0.09 + 32.65 8.99E-05 3.10E-03 cardiac pacemaker cell differentiation (GO:0060920) 11 3 0.09 + 32.65 8.99E-05 3.10E-03 nephric duct morphogenesis (GO:0072178) 11 3 0.09 + 32.65 8.99E-05 3.11E-03 regulation of axon guidance (GO:1902667) 11 3 0.09 + 32.65 8.99E-05 3.12E-03 embryonic skeletal joint morphogenesis (GO:0060272) 11 3 0.09 + 32.65 8.99E-05 3.12E-03 response to organic cyclic compound (GO:0014070) 848 19 7.08 + 2.68 9.08E-05 3.12E-03 cranial nerve formation (GO:0021603) 11 3 0.09 + 32.65 8.99E-05 3.13E-03 central nervous system neuron development (GO:0021954) 87 6 0.73 + 8.26 8.98E-05 3.13E-03 organelle organization (GO:0006996) 3099 9 25.89 - 0.35 9.36E-05 3.21E-03 enteroendocrine cell differentiation (GO:0035883) 29 4 0.24 + 16.51 9.48E-05 3.24E-03 cardiac ventricle development (GO:0003231) 127 7 1.06 + 6.6 9.67E-05 3.30E-03 visual perception (GO:0007601) 220 9 1.84 + 4.9 1.00E-04 3.42E-03 regulation of organ growth (GO:0046620) 89 6 0.74 + 8.07 1.02E-04 3.45E-03 post-embryonic development (GO:0009791) 89 6 0.74 + 8.07 1.02E-04 3.46E-03 response to hormone (GO:0009725) 785 18 6.56 + 2.75 1.05E-04 3.55E-03 response to BMP (GO:0071772) 90 6 0.75 + 7.98 1.08E-04 3.65E-03 cellular response to BMP stimulus (GO:0071773) 90 6 0.75 + 7.98 1.08E-04 3.66E-03 sensory perception of light stimulus (GO:0050953) 223 9 1.86 + 4.83 1.11E-04 3.74E-03 heterocycle biosynthetic process (GO:0018130) 1014 21 8.47 + 2.48 1.16E-04 3.88E-03 mesenchymal cell apoptotic process (GO:0097152) 12 3 0.1 + 29.93 1.19E-04 3.95E-03 ectodermal placode formation (GO:0060788) 12 3 0.1 + 29.93 1.19E-04 3.96E-03 regulation of timing of cell differentiation (GO:0048505) 12 3 0.1 + 29.93 1.19E-04 3.97E-03 ectodermal placode morphogenesis (GO:0071697) 12 3 0.1 + 29.93 1.19E-04 3.98E-03 regulation of development, heterochronic (GO:0040034) 12 3 0.1 + 29.93 1.19E-04 3.98E-03 CD4-positive, alpha-beta T cell differentiation (GO:0043367) 58 5 0.48 + 10.32 1.23E-04 4.06E-03 organonitrogen compound catabolic process (GO:1901565) 1126 0 9.41 - < 0.01 1.26E-04 4.17E-03 regulation of plasma membrane bounded cell projection organization (GO:0120035) 656 16 5.48 + 2.92 1.28E-04 4.23E-03 liver development (GO:0001889) 133 7 1.11 + 6.3 1.29E-04 4.24E-03 primary metabolic process (GO:0044238) 6944 35 58 - 0.6 1.29E-04 4.24E-03 aorta development (GO:0035904) 59 5 0.49 + 10.15 1.33E-04 4.34E-03 aromatic compound biosynthetic process (GO:0019438) 1024 21 8.55 + 2.46 1.33E-04 4.34E-03 regulation of apoptotic process (GO:0042981) 1476 27 12.33 + 2.19 1.33E-04 4.35E-03 response to fibroblast growth factor (GO:0071774) 94 6 0.79 + 7.64 1.38E-04 4.49E-03 aorta morphogenesis (GO:0035909) 32 4 0.27 + 14.97 1.41E-04 4.55E-03 metanephric nephron development (GO:0072210) 32 4 0.27 + 14.97 1.41E-04 4.56E-03 face morphogenesis (GO:0060325) 32 4 0.27 + 14.97 1.41E-04 4.57E-03 hepaticobiliary system development (GO:0061008) 136 7 1.14 + 6.16 1.48E-04 4.78E-03 hypothalamus cell differentiation (GO:0021979) 13 3 0.11 + 27.63 1.54E-04 4.88E-03 cardiac cell fate commitment (GO:0060911) 13 3 0.11 + 27.63 1.54E-04 4.89E-03 motor neuron migration (GO:0097475) 13 3 0.11 + 27.63 1.54E-04 4.90E-03 atrioventricular canal development (GO:0036302) 13 3 0.11 + 27.63 1.54E-04 4.91E-03 midbrain dopaminergic neuron differentiation (GO:1904948) 13 3 0.11 + 27.63 1.54E-04 4.92E-03 metanephric mesenchyme development (GO:0072075) 13 3 0.11 + 27.63 1.54E-04 4.93E-03 regulation of nephron tubule epithelial cell differentiation (GO:0072182) 13 3 0.11 + 27.63 1.54E-04 4.94E-03 telencephalon cell migration (GO:0022029) 61 5 0.51 + 9.81 1.56E-04 4.94E-03 glial cell fate commitment (GO:0021781) 13 3 0.11 + 27.63 1.54E-04 4.95E-03 T cell differentiation (GO:0030217) 184 8 1.54 + 5.21 1.62E-04 5.10E-03 organic substance metabolic process (GO:0071704) 7437 39 62.12 - 0.63 1.66E-04 5.23E-03 organic substance catabolic process (GO:1901575) 1635 2 13.66 - 0.15 1.67E-04 5.24E-03 regulation of locomotion (GO:0040012) 1042 21 8.7 + 2.41 1.68E-04 5.28E-03 regulation of cell projection organization (GO:0031344) 672 16 5.61 + 2.85 1.69E-04 5.29E-03 response to prostaglandin (GO:0034694) 34 4 0.28 + 14.08 1.79E-04 5.59E-03 cardiac muscle tissue growth (GO:0055017) 34 4 0.28 + 14.08 1.79E-04 5.60E-03 anatomical structure maturation (GO:0071695) 238 9 1.99 + 4.53 1.82E-04 5.65E-03 regulation of programmed cell death (GO:0043067) 1521 27 12.7 + 2.13 1.83E-04 5.67E-03 developmental growth involved in morphogenesis (GO:0060560) 141 7 1.18 + 5.94 1.86E-04 5.75E-03 ectodermal placode development (GO:0071696) 14 3 0.12 + 25.65 1.95E-04 6.00E-03 cardioblast differentiation (GO:0010002) 14 3 0.12 + 25.65 1.95E-04 6.01E-03 lung development (GO:0030324) 189 8 1.58 + 5.07 1.94E-04 6.01E-03 positive regulation of amacrine cell differentiation (GO:1902871) 3 2 0.03 + 79.81 2.07E-04 6.17E-03 mammary placode formation (GO:0060596) 3 2 0.03 + 79.81 2.07E-04 6.19E-03 branchiomeric skeletal muscle development (GO:0014707) 3 2 0.03 + 79.81 2.07E-04 6.20E-03 habenula development (GO:0021986) 3 2 0.03 + 79.81 2.07E-04 6.21E-03 brain segmentation (GO:0035284) 3 2 0.03 + 79.81 2.07E-04 6.22E-03 cardiac jelly development (GO:1905072) 3 2 0.03 + 79.81 2.07E-04 6.23E-03 astrocyte-dopaminergic neuron signaling (GO:0036520) 3 2 0.03 + 79.81 2.07E-04 6.25E-03 positive regulation of mesenchymal cell apoptotic process (GO:2001055) 3 2 0.03 + 79.81 2.07E-04 6.26E-03 olfactory pit development (GO:0060166) 3 2 0.03 + 79.81 2.07E-04 6.27E-03 visceral motor neuron differentiation (GO:0021524) 3 2 0.03 + 79.81 2.07E-04 6.28E-03 heart looping (GO:0001947) 65 5 0.54 + 9.21 2.11E-04 6.29E-03 spinal cord oligodendrocyte cell fate specification (GO:0021530) 3 2 0.03 + 79.81 2.07E-04 6.30E-03 epithalamus development (GO:0021538) 3 2 0.03 + 79.81 2.07E-04 6.31E-03 rhombomere 3 development (GO:0021569) 3 2 0.03 + 79.81 2.07E-04 6.32E-03 regulation of synapse organization (GO:0050807) 242 9 2.02 + 4.45 2.06E-04 6.32E-03 rhombomere morphogenesis (GO:0021593) 3 2 0.03 + 79.81 2.07E-04 6.33E-03 specification of animal organ position (GO:0010159) 3 2 0.03 + 79.81 2.07E-04 6.35E-03 organ growth (GO:0035265) 102 6 0.85 + 7.04 2.16E-04 6.42E-03 respiratory tube development (GO:0030323) 193 8 1.61 + 4.96 2.24E-04 6.64E-03 heart growth (GO:0060419) 36 4 0.3 + 13.3 2.25E-04 6.65E-03 regulation of growth (GO:0040008) 621 15 5.19 + 2.89 2.33E-04 6.87E-03 negative regulation of neurogenesis (GO:0050768) 147 7 1.23 + 5.7 2.40E-04 7.07E-03 nephric duct development (GO:0072176) 15 3 0.13 + 23.94 2.42E-04 7.11E-03 embryonic skeletal joint development (GO:0072498) 15 3 0.13 + 23.94 2.42E-04 7.12E-03 regulation of synapse structure or activity (GO:0050803) 248 9 2.07 + 4.34 2.47E-04 7.23E-03 positive regulation of neuroblast proliferation (GO:0002052) 37 4 0.31 + 12.94 2.50E-04 7.31E-03 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090101) 148 7 1.24 + 5.66 2.50E-04 7.31E-03 morphogenesis of embryonic epithelium (GO:0016331) 149 7 1.24 + 5.62 2.60E-04 7.57E-03 nervous system process (GO:0050877) 1469 26 12.27 + 2.12 2.60E-04 7.59E-03 endocrine pancreas development (GO:0031018) 38 4 0.32 + 12.6 2.78E-04 8.03E-03 cellular response to estradiol stimulus (GO:0071392) 38 4 0.32 + 12.6 2.78E-04 8.04E-03 regulation of cardiac muscle cell proliferation (GO:0060043) 38 4 0.32 + 12.6 2.78E-04 8.06E-03 head morphogenesis (GO:0060323) 38 4 0.32 + 12.6 2.78E-04 8.07E-03 cellular response to ketone (GO:1901655) 107 6 0.89 + 6.71 2.80E-04 8.07E-03 localization (GO:0051179) 4501 19 37.6 - 0.51 2.81E-04 8.08E-03 metabolic process (GO:0008152) 7979 44 66.65 - 0.66 2.86E-04 8.22E-03 cerebellum development (GO:0021549) 108 6 0.9 + 6.65 2.95E-04 8.44E-03 neuroendocrine cell differentiation (GO:0061101) 16 3 0.13 + 22.45 2.96E-04 8.45E-03 kidney mesenchyme development (GO:0072074) 16 3 0.13 + 22.45 2.96E-04 8.47E-03 cell surface receptor signaling pathway (GO:0007166) 2079 33 17.37 + 1.9 2.98E-04 8.49E-03 cardiac ventricle morphogenesis (GO:0003208) 70 5 0.58 + 8.55 2.99E-04 8.52E-03 lung epithelium development (GO:0060428) 39 4 0.33 + 12.28 3.08E-04 8.74E-03 alpha-beta T cell activation (GO:0046631) 109 6 0.91 + 6.59 3.10E-04 8.77E-03 embryonic heart tube morphogenesis (GO:0003143) 71 5 0.59 + 8.43 3.20E-04 8.98E-03 determination of heart left/right asymmetry (GO:0061371) 71 5 0.59 + 8.43 3.20E-04 9.00E-03 negative regulation of nervous system development (GO:0051961) 154 7 1.29 + 5.44 3.18E-04 9.00E-03 response to estrogen (GO:0043627) 71 5 0.59 + 8.43 3.20E-04 9.01E-03 muscle tissue morphogenesis (GO:0060415) 71 5 0.59 + 8.43 3.20E-04 9.03E-03 response to chemical (GO:0042221) 3780 51 31.57 + 1.62 3.24E-04 9.07E-03 positive regulation of growth (GO:0045927) 258 9 2.16 + 4.18 3.30E-04 9.23E-03 cellular response to hormone stimulus (GO:0032870) 506 13 4.23 + 3.08 3.42E-04 9.52E-03 CD4-positive, alpha-beta T cell activation (GO:0035710) 72 5 0.6 + 8.31 3.42E-04 9.53E-03 response to organic substance (GO:0010033) 2467 37 20.61 + 1.8 3.48E-04 9.68E-03 mammary gland epithelial cell differentiation (GO:0060644) 17 3 0.14 + 21.13 3.57E-04 9.87E-03 ganglion development (GO:0061548) 17 3 0.14 + 21.13 3.57E-04 9.88E-03 embryonic digestive tract morphogenesis (GO:0048557) 17 3 0.14 + 21.13 3.57E-04 9.90E-03 regulation of epithelial cell differentiation involved in kidney development (GO:2000696) 17 3 0.14 + 21.13 3.57E-04 9.92E-03 establishment of protein localization (GO:0045184) 1291 1 10.78 - 0.09 3.66E-04 1.01E-02 His-Purkinje system cell differentiation (GO:0060932) 4 2 0.03 + 59.86 4.12E-04 1.11E-02 retinoic acid catabolic process (GO:0034653) 4 2 0.03 + 59.86 4.12E-04 1.11E-02 embryonic nail plate morphogenesis (GO:0035880) 4 2 0.03 + 59.86 4.12E-04 1.12E-02 ureter maturation (GO:0035799) 4 2 0.03 + 59.86 4.12E-04 1.12E-02 atrioventricular canal morphogenesis (GO:1905222) 4 2 0.03 + 59.86 4.12E-04 1.12E-02 diterpenoid catabolic process (GO:0016103) 4 2 0.03 + 59.86 4.12E-04 1.12E-02 glial cell-neuron signaling (GO:0150098) 4 2 0.03 + 59.86 4.12E-04 1.12E-02 club cell differentiation (GO:0060486) 4 2 0.03 + 59.86 4.12E-04 1.13E-02 positive regulation of ureteric bud formation (GO:0072107) 4 2 0.03 + 59.86 4.12E-04 1.13E-02 regulation of ureteric bud formation (GO:0072106) 4 2 0.03 + 59.86 4.12E-04 1.13E-02 response to glycine (GO:1905429) 4 2 0.03 + 59.86 4.12E-04 1.13E-02 anatomical structure arrangement (GO:0048532) 18 3 0.15 + 19.95 4.26E-04 1.14E-02 specification of animal organ identity (GO:0010092) 18 3 0.15 + 19.95 4.26E-04 1.15E-02 cellular response to prostaglandin E stimulus (GO:0071380) 18 3 0.15 + 19.95 4.26E-04 1.15E-02 regulation of cell proliferation involved in heart morphogenesis (GO:2000136) 18 3 0.15 + 19.95 4.26E-04 1.15E-02 cellular response to chemical stimulus (GO:0070887) 2389 36 19.95 + 1.8 4.37E-04 1.17E-02 response to testosterone (GO:0033574) 43 4 0.36 + 11.14 4.50E-04 1.20E-02 embryonic axis specification (GO:0000578) 43 4 0.36 + 11.14 4.50E-04 1.20E-02 muscle organ morphogenesis (GO:0048644) 78 5 0.65 + 7.67 4.95E-04 1.32E-02 organic substance transport (GO:0071702) 1910 4 15.95 - 0.25 4.95E-04 1.32E-02 cardiac right ventricle morphogenesis (GO:0003215) 19 3 0.16 + 18.9 5.03E-04 1.33E-02 regulation of odontogenesis (GO:0042481) 19 3 0.16 + 18.9 5.03E-04 1.34E-02 positive regulation of organ growth (GO:0046622) 45 4 0.38 + 10.64 5.36E-04 1.42E-02 positive regulation of axonogenesis (GO:0050772) 80 5 0.67 + 7.48 5.56E-04 1.47E-02 alpha-beta T cell activation involved in immune response (GO:0002287) 46 4 0.38 + 10.41 5.83E-04 1.53E-02 mammary gland morphogenesis (GO:0060443) 46 4 0.38 + 10.41 5.83E-04 1.54E-02 alpha-beta T cell differentiation involved in immune response (GO:0002293) 46 4 0.38 + 10.41 5.83E-04 1.54E-02 somite development (GO:0061053) 81 5 0.68 + 7.39 5.89E-04 1.54E-02 striated muscle cell differentiation (GO:0051146) 223 8 1.86 + 4.29 5.88E-04 1.54E-02 establishment of localization (GO:0051234) 3931 16 32.83 - 0.49 5.91E-04 1.55E-02 negative regulation of cell development (GO:0010721) 281 9 2.35 + 3.83 6.12E-04 1.60E-02 regulation of oligodendrocyte differentiation (GO:0048713) 47 4 0.39 + 10.19 6.34E-04 1.65E-02 prostate gland development (GO:0030850) 47 4 0.39 + 10.19 6.34E-04 1.65E-02 cellular response to oxygen-containing compound (GO:1901701) 1055 20 8.81 + 2.27 6.45E-04 1.67E-02 lens development in camera-type eye (GO:0002088) 83 5 0.69 + 7.21 6.58E-04 1.71E-02 apoptotic process involved in heart morphogenesis (GO:0003278) 5 2 0.04 + 47.89 6.82E-04 1.72E-02 ductus arteriosus closure (GO:0097070) 5 2 0.04 + 47.89 6.82E-04 1.72E-02 osteoclast proliferation (GO:0002158) 5 2 0.04 + 47.89 6.82E-04 1.73E-02 sinoatrial node cell development (GO:0060931) 5 2 0.04 + 47.89 6.82E-04 1.73E-02 regulation of mesonephros development (GO:0061217) 5 2 0.04 + 47.89 6.82E-04 1.73E-02 macromolecule catabolic process (GO:0009057) 950 0 7.94 - < 0.01 6.71E-04 1.73E-02 spinal cord oligodendrocyte cell differentiation (GO:0021529) 5 2 0.04 + 47.89 6.82E-04 1.74E-02 nephric duct formation (GO:0072179) 5 2 0.04 + 47.89 6.82E-04 1.74E-02 metanephric mesenchymal cell differentiation (GO:0072162) 5 2 0.04 + 47.89 6.82E-04 1.74E-02 embryonic epithelial tube formation (GO:0001838) 126 6 1.05 + 5.7 6.70E-04 1.74E-02 skin development (GO:0043588) 285 9 2.38 + 3.78 6.77E-04 1.74E-02 epidermis development (GO:0008544) 346 10 2.89 + 3.46 6.82E-04 1.74E-02 organic cyclic compound biosynthetic process (GO:1901362) 1150 21 9.61 + 2.19 6.73E-04 1.74E-02 positive regulation of transcription regulatory region DNA binding (GO:2000679) 21 3 0.18 + 17.1 6.82E-04 1.75E-02 mammary gland lobule development (GO:0061377) 21 3 0.18 + 17.1 6.82E-04 1.75E-02 mammary gland alveolus development (GO:0060749) 21 3 0.18 + 17.1 6.82E-04 1.75E-02 cerebral cortex cell migration (GO:0021795) 49 4 0.41 + 9.77 7.43E-04 1.87E-02 macromolecule localization (GO:0033036) 2385 7 19.92 - 0.35 7.49E-04 1.88E-02 negative regulation of myeloid cell differentiation (GO:0045638) 86 5 0.72 + 6.96 7.74E-04 1.94E-02 organ induction (GO:0001759) 22 3 0.18 + 16.33 7.85E-04 1.96E-02 sympathetic nervous system development (GO:0048485) 22 3 0.18 + 16.33 7.85E-04 1.96E-02 type B pancreatic cell differentiation (GO:0003309) 22 3 0.18 + 16.33 7.85E-04 1.96E-02 developmental maturation (GO:0021700) 291 9 2.43 + 3.7 7.84E-04 1.97E-02 T cell differentiation involved in immune response (GO:0002292) 50 4 0.42 + 9.58 8.02E-04 2.00E-02 adult locomotory behavior (GO:0008344) 87 5 0.73 + 6.88 8.16E-04 2.03E-02 proteolysis (GO:0006508) 1212 1 10.12 - 0.1 8.33E-04 2.07E-02 cell-cell signaling (GO:0007267) 1086 20 9.07 + 2.2 8.48E-04 2.10E-02 lymphocyte differentiation (GO:0030098) 296 9 2.47 + 3.64 8.84E-04 2.19E-02 signal transduction involved in regulation of gene expression (GO:0023019) 23 3 0.19 + 15.62 8.97E-04 2.22E-02 developmental process involved in reproduction (GO:0003006) 1000 19 8.35 + 2.27 9.01E-04 2.22E-02 epithelial tube formation (GO:0072175) 134 6 1.12 + 5.36 9.25E-04 2.28E-02 cochlea development (GO:0090102) 52 4 0.43 + 9.21 9.31E-04 2.29E-02 cardiac muscle cell differentiation (GO:0055007) 90 5 0.75 + 6.65 9.51E-04 2.33E-02 bundle of His development (GO:0003166) 6 2 0.05 + 39.91 1.02E-03 2.44E-02 type II pneumocyte differentiation (GO:0060510) 6 2 0.05 + 39.91 1.02E-03 2.44E-02 cell surface receptor signaling pathway involved in heart development (GO:0061311) 6 2 0.05 + 39.91 1.02E-03 2.45E-02 negative regulation of photoreceptor cell differentiation (GO:0046533) 6 2 0.05 + 39.91 1.02E-03 2.45E-02 regulation of photoreceptor cell differentiation (GO:0046532) 6 2 0.05 + 39.91 1.02E-03 2.45E-02 midbrain development (GO:0030901) 91 5 0.76 + 6.58 1.00E-03 2.45E-02 embryonic heart tube left/right pattern formation (GO:0060971) 6 2 0.05 + 39.91 1.02E-03 2.46E-02 sinoatrial node cell differentiation (GO:0060921) 6 2 0.05 + 39.91 1.02E-03 2.46E-02 dedifferentiation (GO:0043696) 6 2 0.05 + 39.91 1.02E-03 2.47E-02 G1 to G0 transition involved in cell differentiation (GO:0070315) 6 2 0.05 + 39.91 1.02E-03 2.47E-02 negative regulation of apoptotic process involved in development (GO:1904746) 6 2 0.05 + 39.91 1.02E-03 2.47E-02 activation of meiosis (GO:0090427) 6 2 0.05 + 39.91 1.02E-03 2.48E-02 cell dedifferentiation (GO:0043697) 6 2 0.05 + 39.91 1.02E-03 2.48E-02 bronchiole development (GO:0060435) 6 2 0.05 + 39.91 1.02E-03 2.49E-02 negative regulation of apoptotic process involved in morphogenesis (GO:1902338) 6 2 0.05 + 39.91 1.02E-03 2.49E-02 organonitrogen compound biosynthetic process (GO:1901566) 1360 2 11.36 - 0.18 1.07E-03 2.56E-02 regulation of cardiac muscle tissue growth (GO:0055021) 54 4 0.45 + 8.87 1.07E-03 2.57E-02 cardiac muscle cell proliferation (GO:0060038) 25 3 0.21 + 14.37 1.15E-03 2.73E-02 retina layer formation (GO:0010842) 25 3 0.21 + 14.37 1.15E-03 2.73E-02 positive regulation of cardiac muscle cell proliferation (GO:0060045) 25 3 0.21 + 14.37 1.15E-03 2.74E-02 neural crest cell migration (GO:0001755) 55 4 0.46 + 8.71 1.15E-03 2.74E-02 neuromuscular process controlling balance (GO:0050885) 55 4 0.46 + 8.71 1.15E-03 2.74E-02 regulation of cell migration (GO:0030334) 940 18 7.85 + 2.29 1.22E-03 2.89E-02 biological process involved in interspecies interaction between organisms (GO:0044419) 1557 3 13.01 - 0.23 1.27E-03 3.01E-02 regulation of respiratory gaseous exchange (GO:0043576) 26 3 0.22 + 13.81 1.29E-03 3.05E-02 response to prostaglandin E (GO:0034695) 26 3 0.22 + 13.81 1.29E-03 3.05E-02 mesenchymal cell migration (GO:0090497) 57 4 0.48 + 8.4 1.32E-03 3.09E-02 respiratory gaseous exchange by respiratory system (GO:0007585) 57 4 0.48 + 8.4 1.32E-03 3.09E-02 cellular response to organic substance (GO:0071310) 1725 27 14.41 + 1.87 1.33E-03 3.11E-02 regulation of cellular response to transforming growth factor beta stimulus (GO:1903844) 144 6 1.2 + 4.99 1.34E-03 3.14E-02 fertilization (GO:0009566) 197 7 1.65 + 4.25 1.37E-03 3.19E-02 regulation of Notch signaling pathway (GO:0008593) 98 5 0.82 + 6.11 1.39E-03 3.25E-02 mammary gland formation (GO:0060592) 7 2 0.06 + 34.21 1.42E-03 3.26E-02 His-Purkinje system development (GO:0003164) 7 2 0.06 + 34.21 1.42E-03 3.26E-02 response to nematode (GO:0009624) 7 2 0.06 + 34.21 1.42E-03 3.27E-02 cardiac muscle cell fate commitment (GO:0060923) 7 2 0.06 + 34.21 1.42E-03 3.27E-02 negative regulation of BMP signaling pathway (GO:0030514) 58 4 0.48 + 8.26 1.40E-03 3.27E-02 cellular process (GO:0009987) 14948 143 124.86 + 1.15 1.43E-03 3.27E-02 amide metabolic process (GO:0043603) 828 0 6.92 - < 0.01 1.42E-03 3.27E-02 optic cup morphogenesis involved in camera-type eye development (GO:0002072) 7 2 0.06 + 34.21 1.42E-03 3.28E-02 semicircular canal morphogenesis (GO:0048752) 7 2 0.06 + 34.21 1.42E-03 3.28E-02 mesenchymal cell differentiation involved in kidney development (GO:0072161) 7 2 0.06 + 34.21 1.42E-03 3.29E-02 mesenchymal cell differentiation involved in renal system development (GO:2001012) 7 2 0.06 + 34.21 1.42E-03 3.29E-02 positive regulation of epithelial cell differentiation involved in kidney development (GO:2000698) 7 2 0.06 + 34.21 1.42E-03 3.30E-02 lymph vessel development (GO:0001945) 27 3 0.23 + 13.3 1.45E-03 3.30E-02 positive regulation of mesenchymal cell proliferation (GO:0002053) 27 3 0.23 + 13.3 1.45E-03 3.30E-02 cardiac epithelial to mesenchymal transition (GO:0060317) 27 3 0.23 + 13.3 1.45E-03 3.31E-02 ventricular cardiac muscle tissue development (GO:0003229) 59 4 0.49 + 8.12 1.50E-03 3.40E-02 tube formation (GO:0035148) 147 6 1.23 + 4.89 1.49E-03 3.40E-02 anterior/posterior axis specification (GO:0009948) 60 4 0.5 + 7.98 1.59E-03 3.61E-02 regulation of heart growth (GO:0060420) 60 4 0.5 + 7.98 1.59E-03 3.62E-02 mesenchymal cell proliferation (GO:0010463) 28 3 0.23 + 12.83 1.61E-03 3.64E-02 adult behavior (GO:0030534) 150 6 1.25 + 4.79 1.65E-03 3.74E-02 protein transport (GO:0015031) 1090 1 9.1 - 0.11 1.69E-03 3.81E-02 negative regulation of cellular response to growth factor stimulus (GO:0090288) 103 5 0.86 + 5.81 1.74E-03 3.92E-02 regulation of animal organ formation (GO:0003156) 29 3 0.24 + 12.38 1.78E-03 4.01E-02 positive regulation of cardiac muscle tissue growth (GO:0055023) 29 3 0.24 + 12.38 1.78E-03 4.02E-02 cardiac muscle cell development (GO:0055013) 62 4 0.52 + 7.72 1.80E-03 4.04E-02 cellular response to alcohol (GO:0097306) 104 5 0.87 + 5.76 1.81E-03 4.06E-02 nitrogen compound transport (GO:0071705) 1528 3 12.76 - 0.24 1.83E-03 4.11E-02 mesodermal cell fate specification (GO:0007501) 8 2 0.07 + 29.93 1.88E-03 4.15E-02 regulation of neuromuscular junction development (GO:1904396) 8 2 0.07 + 29.93 1.88E-03 4.16E-02 terpenoid catabolic process (GO:0016115) 8 2 0.07 + 29.93 1.88E-03 4.16E-02 CD8-positive, alpha-beta T cell differentiation (GO:0043374) 8 2 0.07 + 29.93 1.88E-03 4.17E-02 pronephros development (GO:0048793) 8 2 0.07 + 29.93 1.88E-03 4.18E-02 positive regulation of tooth mineralization (GO:0070172) 8 2 0.07 + 29.93 1.88E-03 4.18E-02 negative regulation of erythrocyte differentiation (GO:0045647) 8 2 0.07 + 29.93 1.88E-03 4.19E-02 positive regulation of mammary gland epithelial cell proliferation (GO:0033601) 8 2 0.07 + 29.93 1.88E-03 4.19E-02 lung vasculature development (GO:0060426) 8 2 0.07 + 29.93 1.88E-03 4.20E-02 regulation of gliogenesis (GO:0014013) 106 5 0.89 + 5.65 1.97E-03 4.34E-02 central nervous system projection neuron axonogenesis (GO:0021952) 30 3 0.25 + 11.97 1.97E-03 4.35E-02 regulation of cell motility (GO:2000145) 1000 18 8.35 + 2.15 2.00E-03 4.39E-02 somitogenesis (GO:0001756) 64 4 0.53 + 7.48 2.02E-03 4.44E-02 regulation of axonogenesis (GO:0050770) 158 6 1.32 + 4.55 2.15E-03 4.71E-02 mononuclear cell differentiation (GO:1903131) 339 9 2.83 + 3.18 2.25E-03 4.92E-02 astrocyte differentiation (GO:0048708) 66 4 0.55 + 7.26 2.26E-03 4.95E-02