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["Supplementary table 8: "]
[]
["Description"]
["The allele-specific co-expression relationships found in naïve, LPS and IFNγ analyses between gene expressoin and methylation level. "]
[]
["Explanations for column names:"]
[]
["Methylation site: Name of the methylation site in the co-expression pair"]
["Gene: Name or ID of the gene in the co-expression pair"]
["GM_cor: refers to the Global Mean Correlation between gene and methylation site pairs within a genotype group."]
["pvalue: The p-value associated with the observed difference in edge weight between conditions"]
["fdr: The false discovery rate (FDR) corrected p-value"]
["zscore: Z-score of the difference in edge weight between conditions"]
["GM_pVal (Global Module p-value): This value represents the statistical significance of the overall difference in co-expression patterns between two groups or conditions. It indicates the likelihood that the observed differences in gene co-expression are due to chance rather than true biological effects."]
["GR_cor (Gene Regulation Correlation): This metric quantifies the correlation between the gene expression levels of two genes within a specific condition or group. A higher GR_cor value indicates a stronger positive or negative correlation between the expression of the two genes."]
["GR_pVal (Global Rank p-value): This p-value is associated with the overall significance of the differential co-expression analysis between two groups or conditions. It indicates the probability of observing the observed differences in gene co-expression patterns by chance."]
["zScoreDiff: refers to the z-score of the difference in edge weights between the two conditions being compared."]
["pValDiff: refers to the p-value associated with the difference in edge weights between two conditions or groups. Edge weights represent the strength of the relationship between pairs of genes in a co-expression network."]
["pValDiff_adj: refers to the adjusted p-value for the difference in edge weights between two conditions."]
["Classes (correlation classes): refer to groups of gene-methylation site pairs that exhibit similar co-expression patterns across different genotype. These classes are identified based on the correlation coefficients between genes within each class."]
["Replication: If the pValDiff_adj is significant across RNA-seq and microarray datasets and classes are the same."]
["Genotypes: For each pair of genes, we consider the coExQTL across three groups of genotypes, including REF/REF (G0), REF/ALT (G1), and ALT/ATL (G2)."]

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