comparison	direction	pathwayId	pathwayName	pValue	pValueAdjusted	genes	numCandidateGenes	numBgGenes	geneRatio	totalGenes	topLevelPathway
DOL_DOL1_vs_DOL0	Down	R-HSA-6798695	Neutrophil degranulation	6.957e-79	6.964e-76	ABCA13;CD177;CEACAM1;CEACAM6;CEACAM8;CHIT1;CLEC4D;CRISP3;FCAR;HP;LCN2;LTF;MMP8;MMP9;OLFM4;OLR1;RETN;SERPINB10;TCN1	19	40	0.475	61	Immune System
DOL_DOL1_vs_DOL0	Down	R-HSA-2168880	Scavenging of heme from plasma	1.114e-7	1.115e-4	CD163;HP	2	40	0.05	61	Vesicle-mediated transport
DOL_DOL3_vs_DOL0	Up	R-HSA-909733	Interferon alpha/beta signaling	1.2639999999999998e-70	1.2649999999999996e-67	IFI35;IFI6;IFIT1;IFIT2;IFIT3;ISG15;MX1;OAS1;OAS2;OAS3;OASL;STAT1;USP18;XAF1	14	201	0.06965174129353234	1111	Immune System
DOL_DOL3_vs_DOL0	Up	R-HSA-877300	Interferon gamma signaling	5.461e-49	5.4659999999999995e-46	GBP1;GBP3;GBP4;GBP5;HLA-DPA1;HLA-DPB1;OAS1;OAS2;OAS3;OASL;STAT1;TRIM22	12	201	0.05970149253731343	1111	Immune System
DOL_DOL3_vs_DOL0	Up	R-HSA-913531	Interferon Signaling	1.375e-33	1.3759999999999998e-30	GBP1;GBP3;GBP4;GBP5;HERC5;HLA-DPA1;HLA-DPB1;IFI35;IFI6;IFIT1;IFIT2;IFIT3;ISG15;MX1;TRIM22;UBE2L6;USP18;XAF1	18	201	0.08955223880597014	1111	Immune System
DOL_DOL3_vs_DOL0	Up	R-HSA-1169408	ISG15 antiviral mechanism	1.591e-19	1.593e-16	HERC5;IFIT1;ISG15;MX1;STAT1;UBE2L6;USP18	7	201	0.03482587064676617	1111	Immune System
DOL_DOL3_vs_DOL0	Up	R-HSA-69205	G1/S-Specific Transcription	9.674e-13	9.684e-10	CDC45;CDC6;CDT1;RRM2;TYMS	5	201	0.024875621890547265	1111	Cell Cycle
DOL_DOL3_vs_DOL0	Down	R-HSA-6798695	Neutrophil degranulation	0	0	ABCA13;ACTR10;ADGRE3;ADGRG3;ALAD;ALOX5;ANPEP;ARG1;ATP6V1D;AZU1;BPI;C5AR1;CAT;CD177;CD55;CD59;CDA;CEACAM1;CEACAM6;CEACAM8;CHI3L1;CHIT1;CKAP4;CLEC4D;CLEC5A;CR1;CREG1;CRISP3;CRISPLD2;CTSB;CTSG;CXCL1;CXCR1;CXCR2;CYSTM1;DEFA3;DOK3;ELANE;FCAR;FCGR2A;FOLR3;FPR1;FPR2;GCA;GPR84;GYG1;HP;HSPA1A;IGF2R;ITGAM;LCN2;LILRB3;LRG1;LTF;MAPK14;MCEMP1;MGAM;MME;MMP25;MMP8;MMP9;MPO;MS4A3;OLFM4;OLR1;ORM1;PADI2;PGLYRP1;PNP;PYGL;QPCT;RAB27A;RETN;RNASE3;S100A12;S100A8;S100A9;S100P;SDCBP;SERPINB10;SLC11A1;SLC2A3;SLCO4C1;SLPI;STOM;TCN1;VNN1	87	796	0.1092964824120603	1111	Immune System
DOL_DOL3_vs_DOL0	Down	R-HSA-189451	Heme biosynthesis	4.424e-46	4.4280000000000004e-43	ALAD;ALAS2;CPOX;FECH;HMBS;PPOX;UROD	7	796	0.008793969849246231	1111	Metabolism
DOL_DOL3_vs_DOL0	Down	R-HSA-1632852	Macroautophagy	7.105e-14	7.112e-11	ATG14;ATG9A;GABARAPL1;GABARAPL2;LAMTOR5;MAP1LC3B;MFN2;MTMR3;PINK1;ULK1;WIPI1;WIPI2	12	796	0.01507537688442211	1111	Autophagy
DOL_DOL3_vs_DOL0	Down	R-HSA-4085001	Sialic acid metabolism	1.119e-13	1.12e-10	CMAS;NPL;ST3GAL2;ST3GAL4;ST6GALNAC2;ST6GALNAC3;ST6GALNAC4	7	796	0.008793969849246231	1111	Metabolism of proteins
DOL_DOL3_vs_DOL0	Down	R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling	1.781e-12	1.783e-9	ALOX5;BCL2L1;BCL6;CEBPD;CXCL8;FOXO3;IL4R;ITGAM;LCN2;MAOA;MMP9;OSM;PIM1;PTGS2;SOCS3	15	796	0.018844221105527637	1111	Immune System
DOL_DOL3_vs_DOL0	Down	R-HSA-1483191	Synthesis of PC	5.956e-9	5.962e-6	ACHE;CHPT1;LPIN2;PCTP;PCYT1B;PHOSPHO1	6	796	0.007537688442211055	1111	Metabolism
DOL_DOL3_vs_DOL0	Down	R-HSA-189445	Metabolism of porphyrins	4.686e-8	4.691e-5	ALAD;ALAS2;BLVRB;CPOX;FECH;HMBS;PPOX;UROD	8	796	0.010050251256281407	1111	Metabolism
DOL_DOL3_vs_DOL0	Down	R-HSA-9020702	Interleukin-1 signaling	5.712e-8	5.718e-5	IL1R1;IL1R2;IL1RAP;IRAK3;MAP2K6;S100A12;SKP1;TAB3	8	796	0.010050251256281407	1111	Immune System
DOL_DOL3_vs_DOL0	Down	R-HSA-1362409	Mitochondrial iron-sulfur cluster biogenesis	6.719e-8	6.726e-5	GLRX5;ISCA1;ISCU	3	796	0.0037688442211055275	1111	Metabolism
DOL_DOL3_vs_DOL0	Down	R-HSA-8849932	Synaptic adhesion-like molecules	1.462e-7	1.463e-4	FLOT1;FLOT2;PTPRF;RTN3	4	796	0.005025125628140704	1111	Neuronal System
DOL_DOL3_vs_DOL0	Down	R-HSA-1462054	Alpha-defensins	2.031e-7	2.033e-4	DEFA3	1	796	0.001256281407035176	1111	Immune System
DOL_DOL3_vs_DOL0	Down	R-HSA-5689896	Ovarian tumor domain proteases	7.058e-7	7.065e-4	OTUD7B;PTEN;TNIP1;YOD1;ZRANB1	5	796	0.00628140703517588	1111	Metabolism of proteins
DOL_DOL7_vs_DOL0	Up	R-HSA-380108	Chemokine receptors bind chemokines	4.7159999999999995e-64	4.720999999999999e-61	CCL5;CCR3;CCR4;CCR9;CXCL10;CXCR3;CXCR6;XCL1;XCL2	9	242	0.0371900826446281	1693	Signal Transduction
DOL_DOL7_vs_DOL0	Up	R-HSA-198933	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	8.618000000000001e-58	8.627e-55	CD160;KLRB1;KLRC1;KLRD1;KLRF1;KLRK1;LAIR2;SH2D1B;SIGLEC1;SIGLEC8;SLAMF7	11	242	0.045454545454545456	1693	Immune System
DOL_DOL7_vs_DOL0	Up	R-HSA-373076	Class A/1 (Rhodopsin-like receptors)	1.3799999999999998e-36	1.3809999999999999e-33	ADORA3;CCL5;CCR3;CCR4;CCR9;CXCL10;CXCR3;CXCR6;CYSLTR2;GPBAR1;GPR68;HRH4;NMUR1;OXTR;PTGDR;PTGDR2;S1PR2;S1PR5;XCL1;XCL2	20	242	0.08264462809917356	1693	Signal Transduction
DOL_DOL7_vs_DOL0	Up	R-HSA-909733	Interferon alpha/beta signaling	3.493e-14	3.496e-11	IFI6;IFIT1;ISG15;MX1;OAS1;OAS2;OAS3;OASL;USP18;XAF1	10	242	0.04132231404958678	1693	Immune System
DOL_DOL7_vs_DOL0	Up	R-HSA-2424491	DAP12 signaling	3.759e-12	3.763e-9	KLRD1;KLRK1	2	242	0.008264462809917356	1693	Immune System
DOL_DOL7_vs_DOL0	Up	R-HSA-1169408	ISG15 antiviral mechanism	6.383e-12	6.389e-9	HERC5;IFIT1;ISG15;MX1;USP18	5	242	0.02066115702479339	1693	Immune System
DOL_DOL7_vs_DOL0	Up	R-HSA-391903	Eicosanoid ligand-binding receptors	1.564e-10	1.566e-7	CYSLTR2;PTGDR;PTGDR2	3	242	0.012396694214876033	1693	Signal Transduction
DOL_DOL7_vs_DOL0	Up	R-HSA-77289	Mitochondrial Fatty Acid Beta-Oxidation	1.523e-9	1.525e-6	ACOT11;ACOT2;ACOT7;ACSF2	4	242	0.01652892561983471	1693	Metabolism
DOL_DOL7_vs_DOL0	Up	R-HSA-5673001	RAF/MAP kinase cascade	7.481e-8	7.488e-5	DLG3;DUSP4;DUSP5;ERBB2;IL2RA;IL2RB;IL5RA;NCAM1	8	242	0.03305785123966942	1693	Signal Transduction
DOL_DOL7_vs_DOL0	Up	R-HSA-8877330	RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	1.565e-7	1.567e-4	CTLA4;FOXP3;IL2RA;NFATC2	4	242	0.01652892561983471	1693	Gene expression
DOL_DOL7_vs_DOL0	Up	R-HSA-877300	Interferon gamma signaling	6.261e-7	6.267e-4	GBP1;GBP4;NCAM1;OAS1;OAS2;OAS3;OASL	7	242	0.028925619834710745	1693	Immune System
DOL_DOL7_vs_DOL0	Down	R-HSA-6798695	Neutrophil degranulation	0	0	ABCA13;ACTR10;ADGRG3;ALAD;ALOX5;AMPD3;ANPEP;ARG1;ATP6V1D;AZU1;BPI;BST1;C5AR1;CAB39;CAT;CD177;CD55;CD58;CD59;CDA;CEACAM1;CEACAM3;CEACAM6;CEACAM8;CHIT1;CKAP4;CLEC4D;CLEC5A;CR1;CREG1;CRISP3;CRISPLD2;CTSB;CTSG;CXCL1;CXCR1;CXCR2;CYB5R3;CYSTM1;DEFA3;DEFA4;DOK3;DYNLL1;ELANE;FCAR;FCER1G;FCGR2A;FCGR3B;FOLR3;FPR1;FPR2;FTH1;FTL;GCA;GPR84;GYG1;HK3;HP;HSPA1A;HSPA1B;HSPA6;IGF2R;ITGAM;ITGAX;KRT1;LCN2;LGALS3;LILRB3;LRG1;LTF;MAPK14;MCEMP1;MGAM;MMP25;MMP8;MMP9;MPO;MS4A3;OLFM4;OLR1;ORM1;ORMDL3;PA2G4;PADI2;PGLYRP1;PNP;PRDX6;PTAFR;PTX3;PYGL;QPCT;QSOX1;RAB27A;RAB6A;RETN;S100A11;S100A12;S100A8;S100A9;S100P;SDCBP;SERPINA1;SERPINB1;SERPINB10;SIGLEC5;SIGLEC9;SIRPA;SIRPB1;SLC11A1;SLC15A4;SLC2A3;SLCO4C1;SLPI;STOM;TCN1;TLR2;TMBIM1;TNFAIP6;TUBB4B;VNN1;YPEL5	121	1257	0.09626093874303898	1693	Immune System
DOL_DOL7_vs_DOL0	Down	R-HSA-1632852	Macroautophagy	3.2299999999999995e-65	3.2329999999999995e-62	ATG14;ATG4A;ATG4D;ATG9A;BECN1;CHMP4B;DYNLL1;GABARAP;GABARAPL1;GABARAPL2;LAMTOR5;MAP1LC3B;MFN2;MTMR3;PINK1;RB1CC1;RRAGA;RRAGB;WDR45;WIPI1;WIPI2	21	1257	0.016706443914081145	1693	Autophagy
DOL_DOL7_vs_DOL0	Down	R-HSA-189451	Heme biosynthesis	5.397e-37	5.402e-34	ALAD;ALAS2;CPOX;FECH;HMBS;PPOX;UROD	7	1257	0.005568814638027049	1693	Metabolism
DOL_DOL7_vs_DOL0	Down	R-HSA-2262752	Cellular responses to stress	5.4939999999999996e-30	5.4989999999999996e-27	ACTR10;AGO4;AKT1S1;BAG1;CAT;CCS;CDC16;CDC27;CDKN2D;CEBPB;CITED2;CXCL8;DCTN4;DNAJA4;DYNLL1;E2F2;ELOB;ETS2;FKBP5;FOS;FZR1;GPX1;H1F0;H2AFJ;H3F3B;HIGD1A;HIST1H1C;HIST1H2BD;HSPA13;HSPA1A;HSPA1B;HSPA6;KDM6B;LMNB1;MAP2K3;MAP2K6;MAP2K7;MAP4K4;MAPK14;NCF4;NUP98;PHC2;PRDX1;PRDX2;PRDX5;PRDX6;RBX1;SOD1;SOD2;ST13;TCEB2;TERF2IP;TFDP1;TFDP2;TUBA1A;TUBB2A;TUBB4B;TXN;TXNRD2;UBE2D1;UBE2D3	61	1257	0.04852824184566428	1693	Cell responses to stimuli
DOL_DOL7_vs_DOL0	Down	R-HSA-4085001	Sialic acid metabolism	3.427e-24	3.4300000000000004e-21	CMAS;NANS;NPL;ST3GAL1;ST3GAL2;ST3GAL4;ST6GALNAC2;ST6GALNAC3;ST6GALNAC4;ST8SIA1	10	1257	0.007955449482895784	1693	Metabolism of proteins
DOL_DOL7_vs_DOL0	Down	R-HSA-9020702	Interleukin-1 signaling	3.3239999999999997e-22	3.327e-19	IL1B;IL1R1;IL1R2;IL1RAP;IL1RN;IRAK3;MAP2K6;NFKBIA;PELI1;RBX1;S100A12;SKP1;TAB2;TAB3	14	1257	0.011137629276054098	1693	Immune System
DOL_DOL7_vs_DOL0	Down	R-HSA-3299685	Detoxification of Reactive Oxygen Species	1.455e-19	1.456e-16	CAT;CCS;GPX1;NCF4;PRDX1;PRDX2;PRDX5;PRDX6;SOD1;SOD2;TXN;TXNRD2	12	1257	0.00954653937947494	1693	Cell responses to stimuli
DOL_DOL7_vs_DOL0	Down	R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling	4.993e-19	4.998e-16	ALOX5;BCL2L1;BCL6;CEBPD;CXCL8;FOS;FOXO3;HGF;IL13RA1;IL1B;IL4R;ITGAM;ITGAX;JUNB;LCN2;MAOA;MMP9;OSM;PIM1;PTGS2;SOCS3	21	1257	0.016706443914081145	1693	Immune System
DOL_DOL7_vs_DOL0	Down	R-HSA-8951664	Neddylation	1.132e-15	1.133e-12	ANKRD9;ASB7;COPS2;COPS3;CUL4A;DCAF10;DCAF11;DCAF6;DCUN1D1;DDB1;ELOB;FBXL13;FBXL4;FBXL5;FBXO30;FBXO7;FBXO9;FEM1A;KBTBD7;KLHL2;RBX1;SKP1;SOCS3;SPSB3;TCEB2;UBE2D1;UBE2D3;UBE2F;UBE2M;WDTC1	30	1257	0.02386634844868735	1693	Metabolism of proteins
DOL_DOL7_vs_DOL0	Down	R-HSA-917937	Iron uptake and transport	6.639e-13	6.646e-10	ABCG2;ATP6V1C1;ATP6V1D;CYBRD1;FBXL5;FTH1;FTL;LCN2;MCOLN1;SKP1;SLC40A1;STEAP3;TFR2;TFRC	14	1257	0.011137629276054098	1693	Transport small molecules
DOL_DOL7_vs_DOL0	Down	R-HSA-8856825	Cargo recognition for clathrin-mediated endocytosis	5.519e-12	5.525e-9	AGFG1;AP2A1;AP2B1;AP2M1;AP2S1;COPS2;COPS3;FCHO2;IGF2R;ITSN1;PICALM;REPS2;SGIP1;SH3GL1;STAM;TFRC;TGFA;UBQLN1	18	1257	0.014319809069212411	1693	Vesicle-mediated transport
DOL_DOL7_vs_DOL0	Down	R-HSA-432722	Golgi Associated Vesicle Biogenesis	3.263e-11	3.266e-8	ARF1;BLOC1S6;CPD;DNAJC6;FTH1;FTL;IGF2R;NAPA;PICALM;TFRC;YIPF6	11	1257	0.008750994431185362	1693	Vesicle-mediated transport
DOL_DOL7_vs_DOL0	Down	R-HSA-202733	Cell surface interactions at the vascular wall	9.454e-11	9.463e-8	ATP1B2;BSG;CD177;CD58;CEACAM1;CEACAM3;CEACAM6;CEACAM8;FCER1G;GYPA;GYPB;GYPC;ITGAM;ITGAX;LYN;MERTK;OLR1;SIRPA;SLC16A1;SLC7A5;THBD;TREM1	22	1257	0.017501988862370723	1693	Hemostasis
DOL_DOL7_vs_DOL0	Down	R-HSA-1462054	Alpha-defensins	1.153e-10	1.154e-7	DEFA3;DEFA4	2	1257	0.0015910898965791568	1693	Immune System
DOL_DOL7_vs_DOL0	Down	R-HSA-1236978	Cross-presentation of soluble exogenous antigens (endosomes)	1.672e-8	1.674e-5	FCGR1A;FCGR1B;MRC2	3	1257	0.002386634844868735	1693	Immune System
DOL_DOL7_vs_DOL0	Down	R-HSA-166016	Toll Like Receptor 4 (TLR4) Cascade	1.939e-8	1.941e-5	BIRC2;BPI;ECSIT;FOS;IRAK3;ITGAM;LY96;MAP2K3;MAP2K6;MAP2K7;MAPK14;NFKBIA;PELI1;S100A12;SKP1;TAB2;TAB3;TANK;TLR1;TLR2;TLR4;TLR6;UBE2D1;UBE2D3	24	1257	0.01909307875894988	1693	Immune System
DOL_DOL7_vs_DOL0	Down	R-HSA-380972	Energy dependent regulation of mTOR by LKB1-AMPK	2.662e-8	2.665e-5	CAB39;LAMTOR5;PPM1A;RRAGA;RRAGB;STK11;STRADB	7	1257	0.005568814638027049	1693	Signal Transduction
DOL_DOL7_vs_DOL0	Down	R-HSA-174403	Glutathione synthesis and recycling	5.096e-8	5.101e-5	CHAC2;GCLC;GCLM;OPLAH	4	1257	0.0031821797931583136	1693	Metabolism
DOL_DOL7_vs_DOL0	Down	R-HSA-9612973	Autophagy	1.073e-7	1.074e-4	ATG14;ATG4A;ATG4D;ATG9A;BECN1;DYNLL1;GABARAP;GABARAPL1;GABARAPL2;LAMTOR5;MAP1LC3B;MFN2;MTMR3;PINK1;PLIN3;RB1CC1;RRAGA;RRAGB;TSG101;UBAP1;VPS28;WDR45;WIPI1;WIPI2	24	1257	0.01909307875894988	1693	Autophagy
DOL_DOL7_vs_DOL0	Down	R-HSA-350562	Regulation of ornithine decarboxylase (ODC)	1.7e-7	1.702e-4	OAZ1;OAZ2;ODC1	3	1257	0.002386634844868735	1693	Metabolism
DOL_DOL7_vs_DOL0	Down	R-HSA-352230	Amino acid transport across the plasma membrane	2.025e-7	2.027e-4	SLC1A5;SLC36A1;SLC38A5;SLC43A1;SLC6A19;SLC6A6;SLC7A5	7	1257	0.005568814638027049	1693	Transport small molecules