geneID	length	WT1.rawreads	WT1.FPKM	WT3.rawreads	WT3.FPKM	KO1.rawreads	KO1.FPKM	KO2.rawreads	KO2.FPKM	baseMean	foldchange	log2FoldChange	lfcSE	stat	pvalue	padj	Regulation	Chr	Start	End	Strand	GeneSymbol	Description	GO_BP	GO_CC	GO_MF	KO	Pathway
ENSMUSG00000036928	5733	58	0.53	38	0.38	1437	11.53	1248	12.96	701.733406923929	29.1976078406063	4.86777826886022	0.221578876460927	21.9686025428448	5.75108813359209e-107	8.81871854405011e-103	Ups	5	138278502	138310655	+	Stag3	stromal antigen 3 [Source:MGI Symbol%3BAcc:MGI:1355311]	GO:0007066:female meiosis sister chromatid cohesion;GO:0007129:synapsis;GO:0007065:male meiosis sister chromatid cohesion;GO:0034502:protein localization to chromosome;GO:0007062:sister chromatid cohesion;	GO:0000785:chromatin;GO:0000775:chromosome, centromeric region;GO:0008278:cohesin complex;GO:0000794:condensed nuclear chromosome;GO:0000800:lateral element;GO:0001673:male germ cell nucleus;GO:0030893:meiotic cohesin complex;GO:0034991:nuclear meiotic cohesin complex;GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0000795:synaptonemal complex;GO:0000802:transverse filament;	GO:0003682:chromatin binding;	K13055	;ko04114 Oocyte meiosis;
ENSMUSG00000046434	3153	33482	551.28	30368	548.10	5485	80.05	4002	75.59	17853.6654820778	0.15364295480792	-2.70234648022922	0.146522659078866	-18.443198459664	5.91373009724523e-76	4.53405686555791e-72	Down	15	103148859	103155119	+	Hnrnpa1	heterogeneous nuclear ribonucleoprotein A1 [Source:MGI Symbol%3BAcc:MGI:104820]	GO:0042149:cellular response to glucose starvation;GO:1903936:cellular response to sodium arsenite;GO:0051170:nuclear import;GO:0000398:mRNA splicing, via spliceosome;GO:0051028:mRNA transport;GO:0032211:negative regulation of telomere maintenance via telomerase;GO:0051168:nuclear export;GO:0032212:positive regulation of telomere maintenance via telomerase;GO:0000381:regulation of alternative mRNA splicing, via spliceosome;GO:0006405:RNA export from nucleus;	GO:0071013:catalytic step 2 spliceosome;GO:0005737:cytoplasm;GO:0070062:extracellular exosome;GO:0016020:membrane;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0005681:spliceosomal complex;	GO:0098505:G-rich strand telomeric DNA binding;GO:0042802:identical protein binding;GO:0035198:miRNA binding;GO:0036002:pre-mRNA binding;GO:0019904:protein domain specific binding;GO:0003723:RNA binding;GO:0003697:single-stranded DNA binding;GO:0003727:single-stranded RNA binding;	K12741	;ko03040 Spliceosome;ko05014 Amyotrophic lateral sclerosis;
ENSMUSG00000032028	4102	2217	28.06	2168	30.08	330	3.70	292	4.24	1221.3180543059	0.14774722520797	-2.75879705901107	0.152236923826427	-18.121734134332	2.14719463137444e-73	1.09750274924985e-69	Down	9	48229306	48264754	-	Nxpe2	neurexophilin and PC-esterase domain family%2C member 2 [Source:MGI Symbol%3BAcc:MGI:1925502]	-	GO:0016021:integral component of membrane;	-	-	-
ENSMUSG00000058922	960	2164	117.02	1900	112.63	310	14.86	248	15.39	1125.05376673678	0.142706454643811	-2.80887750518917	0.155609079160943	-18.0508587309614	7.76736406188115e-73	2.97761901312214e-69	Down	9	123518298	123519257	-	Gm10052	predicted pseudogene 10052 [Source:MGI Symbol%3BAcc:MGI:3704348]	GO:0042149:cellular response to glucose starvation;GO:1903936:cellular response to sodium arsenite;GO:0051170:nuclear import;GO:0000398:mRNA splicing, via spliceosome;GO:0051028:mRNA transport;GO:0032211:negative regulation of telomere maintenance via telomerase;GO:0051168:nuclear export;GO:0032212:positive regulation of telomere maintenance via telomerase;GO:0000381:regulation of alternative mRNA splicing, via spliceosome;GO:0006405:RNA export from nucleus;	GO:0071013:catalytic step 2 spliceosome;GO:0005737:cytoplasm;GO:0070062:extracellular exosome;GO:0016020:membrane;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0005681:spliceosomal complex;	GO:0098505:G-rich strand telomeric DNA binding;GO:0042802:identical protein binding;GO:0035198:miRNA binding;GO:0036002:pre-mRNA binding;GO:0019904:protein domain specific binding;GO:0003723:RNA binding;GO:0003697:single-stranded DNA binding;GO:0003727:single-stranded RNA binding;	K12741	;ko03040 Spliceosome;ko05014 Amyotrophic lateral sclerosis;
ENSMUSG00000058794	2988	4	0.07	2	0.04	4140	63.76	2421	48.25	1628.59052214648	1119.01020480332	10.1280074776806	0.620206617777673	16.3300538681308	6.03310576946404e-60	1.85023287737923e-56	Ups	15	103156639	103166830	-	Nfe2	nuclear factor%2C erythroid derived 2 [Source:MGI Symbol%3BAcc:MGI:97308]	GO:0007267:cell-cell signaling;GO:0010467:gene expression;GO:0060716:labyrinthine layer blood vessel development;GO:0030502:negative regulation of bone mineralization;GO:0008285:negative regulation of cell proliferation;GO:0034242:negative regulation of syncytium formation by plasma membrane fusion;GO:2000758:positive regulation of peptidyl-lysine acetylation;GO:0010468:regulation of gene expression;GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005737:cytoplasm;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0016605:PML body;GO:0032993:protein-DNA complex;	GO:0003677:DNA binding;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0042802:identical protein binding;GO:0047485:protein N-terminus binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0050699:WW domain binding;	K09039	-
ENSMUSG00000086000	1997	180	4.68	157	4.47	1165	26.84	1030	30.72	636.852783310881	6.79653135031822	2.76479864629832	0.175233023702936	15.777840203142	4.42057251490843e-56	1.12975098239343e-52	Ups	4	44967730	44972613	+	Gm12493	predicted gene 12493 [Source:MGI Symbol%3BAcc:MGI:3651194]	-	-	-	-	-
ENSMUSG00000004980	6584	35133	277.02	32375	279.82	7169	50.10	7054	63.81	19982.8169292066	0.220939141380854	-2.17827906698752	0.155391954086985	-14.0179656005109	1.21034735673158e-44	2.65135233830314e-41	Down	6	51437912	51446874	-	Hnrnpa2b1	heterogeneous nuclear ribonucleoprotein A2/B1 [Source:MGI Symbol%3BAcc:MGI:104819]	GO:1990428:miRNA transport;GO:0006406:mRNA export from nucleus;GO:0000398:mRNA splicing, via spliceosome;GO:0031053:primary miRNA processing;GO:0044806:G-quadruplex DNA unwinding;GO:0006397:mRNA processing;GO:0050658:RNA transport;	GO:0005737:cytoplasm;GO:0070062:extracellular exosome;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0005681:spliceosomal complex;GO:0015030:Cajal body;GO:0071013:catalytic step 2 spliceosome;GO:0000781:chromosome, telomeric region;GO:0016020:membrane;GO:0016363:nuclear matrix;	GO:0035198:miRNA binding;GO:0003730:mRNA 3'-UTR binding;GO:1990247:N6-methyladenosine-containing RNA binding;GO:0043047:single-stranded telomeric DNA binding;GO:0098505:G-rich strand telomeric DNA binding;GO:0042802:identical protein binding;GO:0003723:RNA binding;	K13158	;ko05014 Amyotrophic lateral sclerosis;
ENSMUSG00000097077	1960	524	13.88	655	19.02	3123	73.32	2457	74.66	1690.53980106427	4.89158234370668	2.29030122798915	0.171648309092628	13.342987414768	1.30137934931527e-40	2.49441886780004e-37	Ups	17	56261771	56266381	-	Gm16712	predicted gene%2C 16712 [Source:MGI Symbol%3BAcc:MGI:4439636]	-	-	-	-	-
ENSMUSG00000031779	2325	34738	775.66	33036	808.59	148841	2945.79	110620	2833.59	81518.9023396052	3.95911204994925	1.98517689879477	0.151101745886159	13.1380143038877	1.99390610203421e-39	3.3971729076214e-36	Ups	8	95472218	95478327	+	Ccl22	chemokine (C-C motif) ligand 22 [Source:MGI Symbol%3BAcc:MGI:1306779]	GO:0071346:cellular response to interferon-gamma;GO:0071347:cellular response to interleukin-1;GO:0071356:cellular response to tumor necrosis factor;GO:0070098:chemokine-mediated signaling pathway;GO:0007186:G-protein coupled receptor signaling pathway;GO:0006954:inflammatory response;GO:0031640:killing of cells of other organism;GO:0048247:lymphocyte chemotaxis;GO:0002548:monocyte chemotaxis;GO:0030593:neutrophil chemotaxis;GO:0070374:positive regulation of ERK1 and ERK2 cascade;GO:0043547:positive regulation of GTPase activity;	GO:0005615:extracellular space;	GO:0048020:CCR chemokine receptor binding;GO:0008009:chemokine activity;	K05514	;ko04060 Cytokine-cytokine receptor interaction;ko04061 Viral protein interaction with cytokine and cytokine receptor;ko04062 Chemokine signaling pathway;
ENSMUSG00000013236	14990	630	2.18	653	2.48	2589	7.95	2036	8.09	1474.81642863475	3.73466541460496	1.90097899902199	0.145989919229802	13.0213031766232	9.25773168758897e-39	1.41958057697489e-35	Ups	17	56719426	56783483	-	Ptprs	protein tyrosine phosphatase%2C receptor type%2C S [Source:MGI Symbol%3BAcc:MGI:97815]	GO:0021549:cerebellum development;GO:0021987:cerebral cortex development;GO:0022038:corpus callosum development;GO:0090557:establishment of endothelial intestinal barrier;GO:0021766:hippocampus development;GO:0050804:regulation of synaptic transmission;GO:0030517:negative regulation of axon extension;GO:0048681:negative regulation of axon regeneration;GO:0048671:negative regulation of collateral sprouting;GO:0061000:negative regulation of dendritic spine development;GO:0032687:negative regulation of interferon-alpha production;GO:0032688:negative regulation of interferon-beta production;GO:0010977:negative regulation of neuron projection development;GO:0034164:negative regulation of toll-like receptor 9 signaling pathway;GO:0035335:peptidyl-tyrosine dephosphorylation;GO:0006470:protein dephosphorylation;GO:0021510:spinal cord development;GO:0050808:synapse organization;GO:0007157:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0046426:negative regulation of JAK-STAT cascade;GO:0030182:neuron differentiation;GO:0050775:positive regulation of dendrite morphogenesis;GO:0051965:positive regulation of synapse assembly;GO:0097105:presynaptic membrane assembly;GO:0050776:regulation of immune response;	GO:0030424:axon;GO:0005829:cytosol;GO:0030426:growth cone;GO:0030285:integral component of synaptic vesicle membrane;GO:0043204:perikaryon;GO:0005886:plasma membrane;GO:0005887:integral component of plasma membrane;	GO:0035374:chondroitin sulfate binding;GO:0043395:heparan sulfate proteoglycan binding;GO:0008201:heparin binding;GO:0004721:phosphoprotein phosphatase activity;GO:0004725:protein tyrosine phosphatase activity;GO:0042803:protein homodimerization activity;GO:0050839:cell adhesion molecule binding;GO:0005102:receptor binding;	K06778	-
ENSMUSG00000039783	4724	5815	63.90	4834	58.23	1542	15.02	1409	17.76	3325.6052113517	0.289907158813564	-1.7863371359023	0.14732008994147	-12.1255501310921	7.73391014094153e-34	1.07810707364725e-30	Down	1	175447947	175489682	+	Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) [Source:MGI Symbol%3BAcc:MGI:2138151]	GO:0034354:'de novo' NAD biosynthetic process from tryptophan;GO:0007568:aging;GO:0043420:anthranilate metabolic process;GO:0071347:cellular response to interleukin-1;GO:0071222:cellular response to lipopolysaccharide;GO:0034276:kynurenic acid biosynthetic process;GO:0070189:kynurenine metabolic process;GO:0097052:L-kynurenine metabolic process;GO:0019674:NAD metabolic process;GO:0014049:positive regulation of glutamate secretion;GO:1903296:positive regulation of glutamate secretion, neurotransmission;GO:1901216:positive regulation of neuron death;GO:0019805:quinolinate biosynthetic process;GO:0009651:response to salt stress;GO:0006569:tryptophan catabolic process;	GO:0005615:extracellular space;GO:0016021:integral component of membrane;GO:0005743:mitochondrial inner membrane;GO:0005741:mitochondrial outer membrane;GO:0005739:mitochondrion;	GO:0071949:FAD binding;GO:0050660:flavin adenine dinucleotide binding;GO:0004502:kynurenine 3-monooxygenase activity;GO:0016174:NAD(P)H oxidase activity;	K00486	;ko00380 Tryptophan metabolism;ko01100 Metabolic pathways;ko01240 Biosynthesis of cofactors;
ENSMUSG00000020713	862	132	7.95	178	11.75	1766	94.27	873	60.32	725.069279325613	8.60941669435995	3.10591549538503	0.260696013148809	11.9139355369126	1.00136863999244e-32	1.279582227137e-29	Ups	11	106191097	106192691	-	Gh	growth hormone [Source:MGI Symbol%3BAcc:MGI:95707]	GO:0048513:organ development;GO:0071469:cellular response to alkaline pH;GO:0032869:cellular response to insulin stimulus;GO:0097067:cellular response to thyroid hormone stimulus;GO:0007565:female pregnancy;GO:0060396:growth hormone receptor signaling pathway;GO:0048286:lung alveolus development;GO:1901215:negative regulation of neuron death;GO:0007405:neuroblast proliferation;GO:0010828:positive regulation of glucose transport;GO:0045927:positive regulation of growth;GO:0040018:positive regulation of multicellular organism growth;GO:0050769:positive regulation of neurogenesis;GO:0046427:positive regulation of JAK-STAT cascade;GO:0090031:positive regulation of steroid hormone biosynthetic process;GO:0042531:positive regulation of tyrosine phosphorylation of STAT protein;GO:0033143:regulation of intracellular steroid hormone receptor signaling pathway;GO:0034097:response to cytokine;GO:0032355:response to estradiol;GO:0032094:response to food;GO:0009416:response to light stimulus;GO:0031667:response to nutrient levels;	GO:0005829:cytosol;GO:0005576:extracellular region;GO:0005615:extracellular space;GO:0005739:mitochondrion;GO:0005634:nucleus;GO:0005886:plasma membrane;GO:0030141:secretory granule;GO:0005802:trans-Golgi network;	GO:0008083:growth factor activity;GO:0005131:growth hormone receptor binding;GO:0005179:hormone activity;GO:0046872:metal ion binding;	K05438	;ko04060 Cytokine-cytokine receptor interaction;ko04080 Neuroactive ligand-receptor interaction;ko04151 PI3K-Akt signaling pathway;ko04630 JAK-STAT signaling pathway;ko04935 Growth hormone synthesis, secretion and action;
ENSMUSG00000024300	4970	645	6.74	651	7.45	123	1.14	122	1.46	376.921318028109	0.197474679576997	-2.3402604137016	0.203470759737468	-11.501703815925	1.29336780704278e-30	1.52557707332262e-27	Down	17	33774681	33826738	+	Myo1f	myosin IF [Source:MGI Symbol%3BAcc:MGI:107711]	GO:0007015:actin filament organization;GO:0030050:vesicle transport along actin filament;GO:0050830:defense response to Gram-positive bacterium;GO:0007162:negative regulation of cell adhesion;GO:0043312:neutrophil degranulation;GO:0002446:neutrophil mediated immunity;GO:0030335:positive regulation of cell migration;GO:0032956:regulation of actin cytoskeleton organization;GO:0045088:regulation of innate immune response;GO:0009617:response to bacterium;	GO:0015629:actin cytoskeleton;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005902:microvillus;GO:0005886:plasma membrane;GO:0016461:unconventional myosin complex;GO:0031982:vesicle;GO:0030864:cortical actin cytoskeleton;GO:0031941:filamentous actin;GO:0016459:myosin complex;	GO:0003779:actin binding;GO:0051015:actin filament binding;GO:0005524:ATP binding;GO:0005516:calmodulin binding;GO:0000146:microfilament motor activity;	K10356	;ko05130 Pathogenic Escherichia coli infection;
ENSMUSG00000030790	1619	112	3.59	104	3.66	658	18.70	465	17.11	333.374738674779	5.36902898178831	2.42466119252546	0.212060977160934	11.4337924166282	2.83452815309065e-30	3.10461819282086e-27	Ups	7	110226868	110229027	+	Adm	adrenomedullin [Source:MGI Symbol%3BAcc:MGI:108058]	GO:0007189:adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:1990410:adrenomedullin receptor signaling pathway;GO:0007568:aging;GO:0097647:amylin receptor signaling pathway;GO:0008209:androgen metabolic process;GO:0031100:organ regeneration;GO:0019731:antibacterial humoral response;GO:0060670:branching involved in labyrinthine layer morphogenesis;GO:0055074:calcium ion homeostasis;GO:0019933:cAMP-mediated signaling;GO:0050829:defense response to Gram-negative bacterium;GO:0050830:defense response to Gram-positive bacterium;GO:0048589:developmental growth;GO:0007565:female pregnancy;GO:0002031:G-protein coupled receptor internalization;GO:0007507:heart development;GO:0046879:hormone secretion;GO:0008285:negative regulation of cell proliferation;GO:0043116:negative regulation of vascular permeability;GO:0045906:negative regulation of vasoconstriction;GO:0001843:neural tube closure;GO:0031102:neuron projection regeneration;GO:0042475:odontogenesis of dentin-containing tooth;GO:0045766:positive regulation of angiogenesis;GO:0043065:positive regulation of apoptotic process;GO:0008284:positive regulation of cell proliferation;GO:0007204:positive regulation of cytosolic calcium ion concentration;GO:0010460:positive regulation of heart rate;GO:2001214:positive regulation of vasculogenesis;GO:0031623:receptor internalization;GO:0003073:regulation of systemic arterial blood pressure;GO:0002026:regulation of the force of heart contraction;GO:0035809:regulation of urine volume;GO:0009409:response to cold;GO:0051384:response to glucocorticoid;GO:0001666:response to hypoxia;GO:0032868:response to insulin;GO:0032496:response to lipopolysaccharide;GO:0042594:response to starvation;GO:0009611:response to wounding;GO:0060712:spongiotrophoblast layer development;GO:0097084:vascular smooth muscle cell development;GO:0001570:vasculogenesis;	GO:0005737:cytoplasm;GO:0005615:extracellular space;	GO:0031700:adrenomedullin receptor binding;GO:0005179:hormone activity;	K12333	;ko04080 Neuroactive ligand-receptor interaction;ko04270 Vascular smooth muscle contraction;
ENSMUSG00000026249	8287	8	0.05	11	0.08	331	1.84	205	1.47	137.917616649761	28.9285607213741	4.85442264173629	0.428240741251137	11.3357328580035	8.72982662840285e-30	8.92421076799529e-27	Ups	1	79771914	79838897	-	Serpine2	serine (or cysteine) peptidase inhibitor%2C clade E%2C member 2 [Source:MGI Symbol%3BAcc:MGI:101780]	GO:0007596:blood coagulation;GO:0021683:cerebellar granular layer morphogenesis;GO:0061110:dense core granule biogenesis;GO:0050974:detection of mechanical stimulus involved in sensory perception;GO:0060384:innervation;GO:0060291:long-term synaptic potentiation;GO:0042628:mating plug formation;GO:0030195:negative regulation of blood coagulation;GO:0030308:negative regulation of cell growth;GO:0008285:negative regulation of cell proliferation;GO:0010951:negative regulation of endopeptidase activity;GO:0010466:negative regulation of peptidase activity;GO:0014067:negative regulation of phosphatidylinositol 3-kinase signaling;GO:0010757:negative regulation of plasminogen activation;GO:0010544:negative regulation of platelet activation;GO:0090331:negative regulation of platelet aggregation;GO:0042177:negative regulation of protein catabolic process;GO:0010955:negative regulation of protein processing;GO:0045861:negative regulation of proteolysis;GO:0045879:negative regulation of smoothened signaling pathway;GO:0010766:negative regulation of sodium ion transport;GO:0048711:positive regulation of astrocyte differentiation;GO:0010976:positive regulation of neuron projection development;GO:0051966:regulation of synaptic transmission, glutamatergic;GO:0048505:regulation of timing of cell differentiation;GO:0009611:response to wounding;GO:0032940:secretion by cell;GO:0033363:secretory granule organization;GO:0061108:seminal vesicle epithelium development;	GO:0005829:cytosol;GO:0005576:extracellular region;GO:0005615:extracellular space;GO:0031232:extrinsic component of external side of plasma membrane;GO:0016020:membrane;GO:0031594:neuromuscular junction;GO:0043025:neuronal cell body;GO:0031091:platelet alpha granule;	GO:0005539:glycosaminoglycan binding;GO:0008201:heparin binding;GO:0004867:serine-type endopeptidase inhibitor activity;GO:0005102:receptor binding;	K16643	-
ENSMUSG00000106734	6765	2086	16.01	1746	14.69	621	4.22	471	4.15	1201.93512822847	0.295676423944633	-1.75790888157508	0.155172729081461	-11.328723107346	9.4573374698829e-30	9.06367579769903e-27	Down	6	3333191	3346128	-	Gm20559	predicted gene%2C 20559 [Source:MGI Symbol%3BAcc:MGI:5295666]	-	-	-	-	-
ENSMUSG00000028602	3459	51	0.77	30	0.49	412	5.48	314	5.41	201.839282336365	9.3152526142515	3.21959489320194	0.28435134146215	11.3225943533328	1.01425158728446e-29	9.14854931730579e-27	Ups	4	144993707	145041734	-	Tnfrsf8	tumor necrosis factor receptor superfamily%2C member 8 [Source:MGI Symbol%3BAcc:MGI:99908]	GO:0043065:positive regulation of apoptotic process;GO:0051092:positive regulation of NF-kappaB transcription factor activity;GO:0032759:positive regulation of TRAIL production;GO:0032760:positive regulation of tumor necrosis factor production;GO:0007165:signal transduction;	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0004888:transmembrane signaling receptor activity;	K05145	;ko04060 Cytokine-cytokine receptor interaction;
ENSMUSG00000025804	2833	1600	29.32	1733	34.81	520	8.45	433	9.10	1050.24666879961	0.2967813014618	-1.75252789625118	0.157180566941234	-11.1497746213525	7.17879665011324e-29	6.11553710182424e-26	Down	9	123762161	123768729	-	Ccr1	chemokine (C-C motif) receptor 1 [Source:MGI Symbol%3BAcc:MGI:104618]	GO:0006816:calcium ion transport;GO:0019722:calcium-mediated signaling;GO:0060326:cell chemotaxis;GO:0007267:cell-cell signaling;GO:0006874:cellular calcium ion homeostasis;GO:0021549:cerebellum development;GO:0070098:chemokine-mediated signaling pathway;GO:0006887:exocytosis;GO:0006955:immune response;GO:0006954:inflammatory response;GO:0030595:leukocyte chemotaxis;GO:0030099:myeloid cell differentiation;GO:0030502:negative regulation of bone mineralization;GO:0010629:negative regulation of gene expression;GO:0045824:negative regulation of innate immune response;GO:0051928:positive regulation of calcium ion transport;GO:0030335:positive regulation of cell migration;GO:0007204:positive regulation of cytosolic calcium ion concentration;GO:0070374:positive regulation of ERK1 and ERK2 cascade;GO:0090026:positive regulation of monocyte chemotaxis;GO:0045672:positive regulation of osteoclast differentiation;	GO:0005737:cytoplasm;GO:0009897:external side of plasma membrane;GO:0016021:integral component of membrane;GO:0043025:neuronal cell body;GO:0005886:plasma membrane;	GO:0019957:C-C chemokine binding;GO:0016493:C-C chemokine receptor activity;GO:0071791:chemokine (C-C motif) ligand 5 binding;GO:0035717:chemokine (C-C motif) ligand 7 binding;GO:0004950:chemokine receptor activity;GO:0004435:phosphatidylinositol phospholipase C activity;	K04176	;ko04060 Cytokine-cytokine receptor interaction;ko04061 Viral protein interaction with cytokine and cytokine receptor;ko04062 Chemokine signaling pathway;ko05163 Human cytomegalovirus infection;ko05167 Kaposi sarcoma-associated herpesvirus infection;
ENSMUSG00000023067	3553	28	0.41	41	0.66	567	7.34	286	4.79	226.965644853814	12.532151381196	3.6475621967423	0.329680537669303	11.0639294103588	1.87690715051399e-28	1.51476285505166e-25	Ups	17	29309950	29319701	+	Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21) [Source:MGI Symbol%3BAcc:MGI:104556]	GO:0031100:organ regeneration;GO:0034198:cellular response to amino acid starvation;GO:0006974:cellular response to DNA damage stimulus;GO:0031668:cellular response to extracellular stimulus;	GO:0000307:cyclin-dependent protein kinase holoenzyme complex;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0016604:nuclear body;	GO:0030332:cyclin binding;GO:0019912:cyclin-dependent protein kinase activating kinase activity;GO:0004861:cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0046872:metal ion binding;	K06625	;ko01522 Endocrine resistance;ko01524 Platinum drug resistance;ko04012 ErbB signaling pathway;ko04066 HIF-1 signaling pathway;ko04068 FoxO signaling pathway;ko04110 Cell cycle;ko04115 p53 signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04218 Cellular senescence;ko04630 JAK-STAT signaling pathway;ko04921 Oxytocin signaling pathway;ko04928 Parathyroid hormone synthesis, secretion and action;ko04934 Cushing syndrome;ko05160 Hepatitis C;ko05161 Hepatitis B;ko05163 Human cytomegalovirus infection;ko05165 Human papillomavirus infection;ko05166 Human T-cell leukemia virus 1 infection;ko05167 Kaposi sarcoma-associated herpesvirus infection;ko05169 Epstein-Barr virus infection;ko05200 Pathways in cancer;ko05202 Transcriptional misregulation in cancer;ko05203 Viral carcinogenesis;ko05205 Proteoglycans in cancer;ko05206 MicroRNAs in cancer;ko05210 Colorectal cancer;ko05211 Renal cell carcinoma;ko05212 Pancreatic cancer;ko05213 Endometrial cancer;ko05214 Glioma;ko05215 Prostate cancer;ko05216 Thyroid cancer;ko05217 Basal cell carcinoma;ko05218 Melanoma;ko05219 Bladder cancer;ko05220 Chronic myeloid leukemia;ko05222 Small cell lung cancer;ko05223 Non-small cell lung cancer;ko05224 Breast cancer;ko05225 Hepatocellular carcinoma;ko05226 Gastric cancer;
ENSMUSG00000068744	3364	281	4.34	263	4.45	1988	27.19	1021	18.08	873.752732124281	5.62723700698633	2.4924267278531	0.226700787002174	10.9943452813386	4.0685539152193e-28	3.11936028679864e-25	Ups	3	108291155	108295547	+	Psrc1	proline/serine-rich coiled-coil 1 [Source:MGI Symbol%3BAcc:MGI:1913099]	GO:0051301:cell division;GO:0009987:cellular process;GO:0001578:microtubule bundle formation;GO:0007080:mitotic metaphase plate congression;GO:0030308:negative regulation of cell growth;GO:0045737:positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0031116:positive regulation of microtubule polymerization;GO:0045893:positive regulation of transcription, DNA-templated;GO:0060236:regulation of mitotic spindle organization;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0015630:microtubule cytoskeleton;GO:0030496:midbody;GO:0005654:nucleoplasm;GO:0005819:spindle;GO:0005876:spindle microtubule;GO:0000922:spindle pole;	GO:0008017:microtubule binding;	-	-
ENSMUSG00000022996	3401	528	8.06	484	8.10	1626	22.00	1372	24.03	1001.9421028153	3.08360702088996	1.62461891793191	0.148429181799152	10.9454144949089	6.98972860192089e-28	5.1038332562788e-25	Ups	15	98668593	98676031	-	Wnt10b	wingless-type MMTV integration site family%2C member 10B [Source:MGI Symbol%3BAcc:MGI:108061]	GO:0009887:organ morphogenesis;GO:0060346:bone trabecula formation;GO:0060070:canonical Wnt signaling pathway;GO:0045165:cell fate commitment;GO:0007267:cell-cell signaling;GO:0071320:cellular response to cAMP;GO:0071407:cellular response to organic cyclic compound;GO:0071310:cellular response to organic substance;GO:0071374:cellular response to parathyroid hormone stimulus;GO:0002062:chondrocyte differentiation;GO:0061196:fungiform papilla development;GO:0000086:G2/M transition of mitotic cell cycle;GO:0071425:hematopoietic stem cell proliferation;GO:0006629:lipid metabolic process;GO:0014835:myoblast differentiation involved in skeletal muscle regeneration;GO:0050680:negative regulation of epithelial cell proliferation;GO:0045599:negative regulation of fat cell differentiation;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0030182:neuron differentiation;GO:0043065:positive regulation of apoptotic process;GO:0030501:positive regulation of bone mineralization;GO:0090263:positive regulation of canonical Wnt signaling pathway;GO:0008284:positive regulation of cell proliferation;GO:0051091:positive regulation of sequence-specific DNA binding transcription factor activity;GO:0030858:positive regulation of epithelial cell differentiation;GO:0010971:positive regulation of G2/M transition of mitotic cell cycle;GO:0045778:positive regulation of ossification;GO:0045669:positive regulation of osteoblast differentiation;GO:0045899:positive regulation of RNA polymerase II transcriptional preinitiation complex assembly;GO:0051885:positive regulation of anagen;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0050821:protein stabilization;GO:0051726:regulation of cell cycle;GO:0045598:regulation of fat cell differentiation;GO:0032434:regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0051246:regulation of protein metabolic process;GO:0048641:regulation of skeletal muscle tissue development;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0050909:sensory perception of taste;GO:0007165:signal transduction;GO:0048741:skeletal muscle fiber development;GO:0043403:skeletal muscle tissue regeneration;GO:0007224:smoothened signaling pathway;GO:0016055:Wnt signaling pathway;	GO:0005615:extracellular space;	GO:0005125:cytokine activity;GO:0005109:frizzled binding;GO:0005102:receptor binding;	K01357	;ko04150 mTOR signaling pathway;ko04310 Wnt signaling pathway;ko04390 Hippo signaling pathway;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04916 Melanogenesis;ko04934 Cushing syndrome;ko05010 Alzheimer disease;ko05022 Pathways of neurodegeneration - multiple diseases;ko05165 Human papillomavirus infection;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05217 Basal cell carcinoma;ko05224 Breast cancer;ko05225 Hepatocellular carcinoma;ko05226 Gastric cancer;
ENSMUSG00000078794	2989	61	1.06	72	1.37	872	13.42	396	7.89	343.280624169679	9.63021718358368	3.26756833453249	0.300536076424656	10.8724662057391	1.55928016172402e-27	1.08681827272164e-24	Ups	7	16609242	16621387	+	Dact3	dishevelled-binding antagonist of beta-catenin 3 [Source:MGI Symbol%3BAcc:MGI:3654828]	GO:0090090:negative regulation of canonical Wnt signaling pathway;GO:0030308:negative regulation of cell growth;GO:0010719:negative regulation of epithelial to mesenchymal transition;GO:0030178:negative regulation of Wnt signaling pathway;GO:0016055:Wnt signaling pathway;	GO:0005737:cytoplasm;	GO:0070097:delta-catenin binding;GO:0042802:identical protein binding;GO:0051018:protein kinase A binding;GO:0005080:protein kinase C binding;	-	-
ENSMUSG00000041782	3400	203	3.10	105	1.76	1035	14.01	835	14.63	544.997362443239	6.34591054381507	2.66582718420796	0.246447497111067	10.8170186975222	2.8592736308709e-27	1.90626529807715e-24	Ups	1	135746336	135761080	+	Lad1	ladinin [Source:MGI Symbol%3BAcc:MGI:109343]	-	GO:0015629:actin cytoskeleton;GO:0005604:basement membrane;GO:0005576:extracellular region;	GO:0005198:structural molecule activity;	-	-
ENSMUSG00000058886	4389	346	4.09	400	5.19	1614	16.92	1129	15.32	867.469898621335	3.78440155223335	1.92006517712333	0.178417078616956	10.7616669435862	5.2216963673615e-27	3.33622883738005e-24	Ups	7	140877093	140907603	-	Deaf1	DEAF1%2C transcription factor [Source:MGI Symbol%3BAcc:MGI:1858496]	GO:0001662:behavioral fear response;GO:0048706:embryonic skeletal system development;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0045892:negative regulation of transcription, DNA-templated;GO:0001843:neural tube closure;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-templated;GO:0033599:regulation of mammary gland epithelial cell proliferation;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0008542:visual learning;	GO:0005737:cytoplasm;GO:0001650:fibrillar center;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0090575:RNA polymerase II transcription factor complex;GO:0005576:extracellular region;	GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001227:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0046872:metal ion binding;GO:0000977:RNA polymerase II regulatory region sequence-specific DNA binding;	-	-
ENSMUSG00000018648	1945	259	6.91	236	6.90	1256	29.71	785	24.04	627.732897711732	4.23457396172733	2.08221682806476	0.19489268374742	10.683914798789	1.21056523535772e-26	7.42512292759014e-24	Ups	11	83938867	83960087	-	Dusp14	dual specificity phosphatase 14 [Source:MGI Symbol%3BAcc:MGI:1927168]	-	GO:0005737:cytoplasm;GO:0005634:nucleus;	GO:0017017:MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0004725:protein tyrosine phosphatase activity;	K14165	-
ENSMUSG00000039089	9713	1139	6.09	1096	6.42	355	1.68	316	1.94	711.960673431557	0.312890581337024	-1.67626986380256	0.160540785204188	-10.4413956968664	1.6043435264412e-25	9.46192447478823e-23	Down	10	26150366	26251967	-	L3mbtl3	L3MBTL3 histone methyl-lysine binding protein [Source:MGI Symbol%3BAcc:MGI:2143628]	GO:0006325:chromatin organization;GO:0043249:erythrocyte maturation;GO:0030851:granulocyte differentiation;GO:0030225:macrophage differentiation;GO:0030099:myeloid cell differentiation;GO:0045892:negative regulation of transcription, DNA-templated;	GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0003682:chromatin binding;GO:0042393:histone binding;GO:0042802:identical protein binding;GO:0008270:zinc ion binding;	-	-
ENSMUSG00000042351	6243	1290	10.73	1344	12.25	313	2.31	345	3.29	807.91245674359	0.262368648358901	-1.93033275892318	0.186358917738768	-10.3581453592098	3.8434196439515e-25	2.18277766001305e-22	Down	15	80456795	80537055	+	Grap2	GRB2-related adaptor protein 2 [Source:MGI Symbol%3BAcc:MGI:1333842]	-	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005768:endosome;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0005886:plasma membrane;	-	K07366	;ko04660 T cell receptor signaling pathway;
ENSMUSG00000102813	2459	93	1.96	80	1.85	432	8.08	404	9.78	253.940364103446	5.05429297163339	2.33750929239357	0.229699280230879	10.1763892775113	2.52766923522185e-24	1.384260001889e-21	Ups	4	150152996	150155454	+	Gm37795	predicted gene%2C 37795 [Source:MGI Symbol%3BAcc:MGI:5611023]	-	-	-	-	-
ENSMUSG00000045672	13022	42	0.17	26	0.11	408	1.44	234	1.07	175.470153287228	9.69054882411113	3.27657837496973	0.323519440891981	10.1279180191948	4.15399834779209e-24	2.19646243672565e-21	Ups	4	63132241	63253228	+	Col27a1	collagen%2C type XXVII%2C alpha 1 [Source:MGI Symbol%3BAcc:MGI:2672118]	GO:0030198:extracellular matrix organization;GO:0003431:growth plate cartilage chondrocyte development;	GO:0031012:extracellular matrix;GO:0005615:extracellular space;GO:0005583:fibrillar collagen trimer;	GO:0005201:extracellular matrix structural constituent;GO:0046872:metal ion binding;	K19721;K06236	;ko04974 Protein digestion and absorption;;ko04151 PI3K-Akt signaling pathway;ko04510 Focal adhesion;ko04512 ECM-receptor interaction;ko04611 Platelet activation;ko04926 Relaxin signaling pathway;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko04974 Protein digestion and absorption;ko05146 Amoebiasis;ko05165 Human papillomavirus infection;ko05205 Proteoglycans in cancer;
ENSMUSG00000015340	5808	13021	116.39	11834	115.95	4152	32.90	4090	41.94	8120.34061312626	0.347797464884452	-1.52368067809093	0.152262612947629	-10.0069258539192	1.42099523099621e-23	7.26318029069861e-21	Down	X	9301491	9354010	-	Cybb	cytochrome b-245%2C beta polypeptide [Source:MGI Symbol%3BAcc:MGI:88574]	GO:0071276:cellular response to cadmium ion;GO:0071361:cellular response to ethanol;GO:0006952:defense response;GO:0022900:electron transport chain;GO:0050665:hydrogen peroxide biosynthetic process;GO:0097411:hypoxia-inducible factor-1alpha signaling pathway;GO:0006954:inflammatory response;GO:0045087:innate immune response;GO:0045766:positive regulation of angiogenesis;GO:0032760:positive regulation of tumor necrosis factor production;GO:0034765:regulation of ion transmembrane transport;GO:0045730:respiratory burst;GO:1904044:response to aldosterone;GO:0042493:response to drug;GO:0007584:response to nutrient;GO:0042554:superoxide anion generation;GO:0006801:superoxide metabolic process;	GO:0005737:cytoplasm;GO:0030425:dendrite;GO:0005783:endoplasmic reticulum;GO:0005794:Golgi apparatus;GO:0005887:integral component of plasma membrane;GO:0005739:mitochondrion;GO:0043020:NADPH oxidase complex;GO:0043025:neuronal cell body;GO:0005635:nuclear envelope;GO:0097038:perinuclear endoplasmic reticulum;GO:0045335:phagocytic vesicle;GO:0005886:plasma membrane;GO:0005791:rough endoplasmic reticulum;	GO:0050660:flavin adenine dinucleotide binding;GO:0020037:heme binding;GO:0046872:metal ion binding;GO:0046982:protein heterodimerization activity;GO:0016175:superoxide-generating NADPH oxidase activity;GO:0005244:voltage-gated ion channel activity;	K08008	;ko04380 Osteoclast differentiation;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05010 Alzheimer disease;ko05022 Pathways of neurodegeneration - multiple diseases;ko05418 Fluid shear stress and atherosclerosis;
ENSMUSG00000085156	3010	991	17.09	819	15.48	3739	57.16	2313	45.77	1942.98809691706	3.43524477043533	1.78041289861025	0.179736002950057	9.90571098381982	3.93163540875049e-23	1.94476443089613e-20	Ups	11	6475295	6478841	-	Snhg15	small nucleolar RNA host gene 15 [Source:MGI Symbol%3BAcc:MGI:3650059]	-	-	-	-	-
ENSMUSG00000083161	2958	712	12.50	614	11.81	189	2.94	164	3.30	410.379638731712	0.277514203656458	-1.84936648190992	0.188525972374056	-9.80961115660274	1.02362237211519e-22	4.90507045437948e-20	Down	11	83115280	83151786	+	Gm11427	predicted gene 11427 [Source:MGI Symbol%3BAcc:MGI:3651774]	-	-	-	-	-
ENSMUSG00000041801	1559	20	0.67	11	0.40	385	11.36	167	6.38	142.551539681063	18.064177313663	4.1750596473314	0.426290714757585	9.79392584167731	1.19561423830279e-22	5.55562082731363e-20	Ups	1	135693857	135696874	+	Phlda3	pleckstrin homology like domain%2C family A%2C member 3 [Source:MGI Symbol%3BAcc:MGI:1351485]	GO:0042771:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0051898:negative regulation of protein kinase B signaling;GO:0043065:positive regulation of apoptotic process;	GO:0005737:cytoplasm;GO:0005886:plasma membrane;	GO:0005547:phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043325:phosphatidylinositol-3,4-bisphosphate binding;GO:0080025:phosphatidylinositol-3,5-bisphosphate binding;GO:0032266:phosphatidylinositol-3-phosphate binding;GO:0005546:phosphatidylinositol-4,5-bisphosphate binding;GO:0010314:phosphatidylinositol-5-phosphate binding;	-	-
ENSMUSG00000107215	2583	364	7.32	382	8.42	40	0.71	59	1.36	206.850691105957	0.140052320706805	-2.83596220540954	0.290426914239	-9.76480507269981	1.59418276922306e-22	7.18976428919598e-20	Down	6	3336772	3339354	-	Gm43197	predicted gene 43197 [Source:MGI Symbol%3BAcc:MGI:5663334]	-	-	-	-	-
ENSMUSG00000074578	2930	1602	28.38	1305	25.35	5372	84.37	3487	70.88	2911.35029588978	3.13841954238902	1.65003822396505	0.169508918800347	9.73422658608613	2.15450353622538e-22	9.43918777842284e-20	Ups	2	166904854	166907783	+	Zfas1	zinc finger%2C NFX1-type containing 1%2C antisense RNA 1 [Source:MGI Symbol%3BAcc:MGI:1916199]	-	-	-	-	-
ENSMUSG00000037593	4299	34	0.41	39	0.52	262	2.80	270	3.74	153.323256333664	7.63719900485892	2.93304361696025	0.302464036925972	9.69716481592196	3.09992831172966e-22	1.32039724255729e-19	Ups	11	78181667	78187631	+	Rskr	ribosomal protein S6 kinase related [Source:MGI Symbol%3BAcc:MGI:2652869]	GO:0006468:protein phosphorylation;	-	GO:0005524:ATP binding;GO:0004672:protein kinase activity;	K17529	-
ENSMUSG00000047735	5427	3222	30.82	2832	29.70	1119	9.49	1050	11.52	2016.9616567487	0.374918335936786	-1.41535171039714	0.147091479122233	-9.62225493171484	6.44035520775664e-22	2.66909207447947e-19	Down	6	3372257	3399572	-	Samd9l	sterile alpha motif domain containing 9-like [Source:MGI Symbol%3BAcc:MGI:1343184]	GO:0035726:common myeloid progenitor cell proliferation;GO:0034058:endosomal vesicle fusion;GO:0002244:hematopoietic progenitor cell differentiation;GO:0042176:regulation of protein catabolic process;GO:0048536:spleen development;GO:0017145:stem cell division;	GO:0005737:cytoplasm;GO:0005769:early endosome;	-	-	-
ENSMUSG00000021879	12009	39	0.17	24	0.11	253	0.97	230	1.14	137.526149726436	8.02570559983506	3.00462823592754	0.318246428755144	9.44120016579756	3.68533685661217e-21	1.48713040419187e-18	Ups	14	26414429	26613660	+	Dnah12	dynein%2C axonemal%2C heavy chain 12 [Source:MGI Symbol%3BAcc:MGI:107720]	GO:0003341:cilium movement;GO:0007018:microtubule-based movement;GO:0016567:protein ubiquitination;	GO:0030286:dynein complex;GO:0036156:inner dynein arm;GO:0005874:microtubule;	GO:0005524:ATP binding;GO:0008569:ATP-dependent microtubule motor activity, minus-end-directed;GO:0045505:dynein intermediate chain binding;GO:0051959:dynein light intermediate chain binding;	K10408	;ko05014 Amyotrophic lateral sclerosis;ko05016 Huntington disease;ko05022 Pathways of neurodegeneration - multiple diseases;
ENSMUSG00000048458	4781	23	0.25	29	0.35	247	2.38	186	2.32	121.340575234273	8.60680574590051	3.10547790782058	0.330942103559497	9.38374982940868	6.36672268124127e-21	2.50326475882445e-18	Ups	3	105611915	105628158	+	Inka2	inka box actin regulator 2 [Source:MGI Symbol%3BAcc:MGI:1923497]	-	GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0019901:protein kinase binding;GO:0030291:protein serine/threonine kinase inhibitor activity;	-	-
ENSMUSG00000029581	3012	174	3.00	145	2.74	1219	18.62	550	10.88	510.879420825464	5.61926791030566	2.49038218543387	0.270462677248191	9.20785895773916	3.32694465711007e-20	1.27538423430314e-17	Ups	5	142946098	142958940	+	Fscn1	fascin actin-bundling protein 1 [Source:MGI Symbol%3BAcc:MGI:1352745]	GO:0030036:actin cytoskeleton organization;GO:0051017:actin filament bundle assembly;GO:0016477:cell migration;GO:0048870:cell motility;GO:0007043:cell-cell junction assembly;GO:0035089:establishment of apical/basal cell polarity;GO:0007163:establishment or maintenance of cell polarity;GO:0030035:microspike assembly;GO:0030046:parallel actin filament bundle assembly;GO:0090091:positive regulation of extracellular matrix disassembly;GO:0051491:positive regulation of filopodium assembly;GO:0010592:positive regulation of lamellipodium assembly;GO:0071803:positive regulation of podosome assembly;GO:0032956:regulation of actin cytoskeleton organization;GO:0032534:regulation of microvillus assembly;	GO:0015629:actin cytoskeleton;GO:0005938:cell cortex;GO:0031253:cell projection membrane;GO:0005911:cell-cell junction;GO:0005737:cytoplasm;GO:0005856:cytoskeleton;GO:0005829:cytosol;GO:0030425:dendrite;GO:0030175:filopodium;GO:0030426:growth cone;GO:0030027:lamellipodium;GO:0044393:microspike;GO:0005902:microvillus;GO:0043209:myelin sheath;GO:0005886:plasma membrane;GO:0002102:podosome;GO:0001726:ruffle;GO:0001725:stress fiber;	GO:0003779:actin binding;GO:0051015:actin filament binding;GO:0008144:drug binding;GO:0030674:protein binding, bridging;	K17455	-
ENSMUSG00000044734	2303	1228	27.68	1338	33.06	436	8.71	246	6.36	792.426723957004	0.271511608494998	-1.88091421302664	0.204586010004721	-9.19375774024447	3.7935237276627e-20	1.41877787414585e-17	Down	13	33026075	33035168	-	Serpinb1a	serine (or cysteine) peptidase inhibitor%2C clade B%2C member 1a [Source:MGI Symbol%3BAcc:MGI:1913472]	GO:0019725:cellular homeostasis;GO:0006954:inflammatory response;GO:0010951:negative regulation of endopeptidase activity;GO:0032691:negative regulation of interleukin-1 beta production;GO:0045088:regulation of innate immune response;GO:0042176:regulation of protein catabolic process;GO:0044342:type B pancreatic cell proliferation;	GO:0036464:cytoplasmic ribonucleoprotein granule;GO:0005769:early endosome;GO:0005576:extracellular region;GO:0005615:extracellular space;GO:0005764:lysosome;	GO:0030414:peptidase inhibitor activity;GO:0004867:serine-type endopeptidase inhibitor activity;	K13963	;ko05146 Amoebiasis;
ENSMUSG00000029084	3890	3605	48.11	4081	59.70	1323	15.65	1291	19.77	2533.16449635885	0.35535673374232	-1.49266005734518	0.163159532196021	-9.14846982738273	5.77456570875415e-20	2.10826644233419e-17	Down	5	44025895	44069717	+	Cd38	CD38 antigen [Source:MGI Symbol%3BAcc:MGI:107474]	GO:0014824:artery smooth muscle contraction;GO:0050853:B cell receptor signaling pathway;GO:0007565:female pregnancy;GO:0060292:long term synaptic depression;GO:0043066:negative regulation of apoptotic process;GO:0045779:negative regulation of bone resorption;GO:0010977:negative regulation of neuron projection development;GO:0045892:negative regulation of transcription, DNA-templated;GO:0030890:positive regulation of B cell proliferation;GO:0030307:positive regulation of cell growth;GO:0008284:positive regulation of cell proliferation;GO:0007204:positive regulation of cytosolic calcium ion concentration;GO:0032024:positive regulation of insulin secretion;GO:0045893:positive regulation of transcription, DNA-templated;GO:0045907:positive regulation of vasoconstriction;GO:0042493:response to drug;GO:0032355:response to estradiol;GO:0009725:response to hormone;GO:0033194:response to hydroperoxide;GO:0001666:response to hypoxia;GO:0070555:response to interleukin-1;GO:0032570:response to progesterone;GO:0032526:response to retinoic acid;	GO:0016323:basolateral plasma membrane;GO:0009986:cell surface;GO:0016021:integral component of membrane;GO:0043231:intracellular membrane-bounded organelle;GO:0016020:membrane;GO:0005634:nucleus;GO:0005886:plasma membrane;GO:0030667:secretory granule membrane;	GO:0016798:hydrolase activity, acting on glycosyl bonds;GO:0042802:identical protein binding;GO:0050135:NAD(P)+ nucleosidase activity;GO:0003953:NAD+ nucleosidase activity;GO:0016849:phosphorus-oxygen lyase activity;GO:0016740:transferase activity;	K01242	;ko00760 Nicotinate and nicotinamide metabolism;ko01100 Metabolic pathways;ko04020 Calcium signaling pathway;ko04640 Hematopoietic cell lineage;ko04921 Oxytocin signaling pathway;ko04970 Salivary secretion;ko04972 Pancreatic secretion;
ENSMUSG00000120369	3116	275	4.58	248	4.53	838	12.38	663	12.67	504.388698276535	2.97931820215706	1.57498221696039	0.172525996274183	9.12895593112462	6.91630681588883e-20	2.46638717941487e-17	Ups	2	26527180	26530295	-	-	novel transcript	-	-	-	-	-
ENSMUSG00000031785	5421	479	4.59	431	4.52	1554	13.19	1045	11.48	869.341839345954	2.94320133691207	1.55738623674969	0.170896710229463	9.11302642782645	8.01152869534166e-20	2.79201775032657e-17	Ups	8	95701379	95740845	+	Adgrg1	adhesion G protein-coupled receptor G1 [Source:MGI Symbol%3BAcc:MGI:1340051]	GO:0007189:adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0001525:angiogenesis;GO:0007420:brain development;GO:0007155:cell adhesion;GO:0016477:cell migration;GO:0007166:cell surface receptor signaling pathway;GO:0021801:cerebral cortex radial glia guided migration;GO:0021796:cerebral cortex regionalization;GO:0061484:hematopoietic stem cell homeostasis;GO:0021819:layer formation in cerebral cortex;GO:0008285:negative regulation of cell proliferation;GO:2001223:negative regulation of neuron migration;GO:0045785:positive regulation of cell adhesion;GO:2000179:positive regulation of neural precursor cell proliferation;GO:0035025:positive regulation of Rho protein signal transduction;GO:0070528:protein kinase C signaling;GO:0007266:Rho protein signal transduction;GO:0072520:seminiferous tubule development;GO:0010573:vascular endothelial growth factor production;	GO:0005576:extracellular region;GO:0097451:glial limiting end-foot;GO:0005887:integral component of plasma membrane;GO:0045121:membrane raft;	GO:0005518:collagen binding;GO:0050840:extracellular matrix binding;GO:0004930:G-protein coupled receptor activity;GO:0008201:heparin binding;	K08450	-
ENSMUSG00000034858	6637	2482	19.41	2566	22.00	780	5.41	841	7.55	1639.79917378242	0.337367807971394	-1.56760577833299	0.172350602602968	-9.09544704026463	9.41981447407164e-20	3.20985411434255e-17	Down	9	74860166	74939750	+	Fam214a	family with sequence similarity 214%2C member A [Source:MGI Symbol%3BAcc:MGI:2387648]	-	-	-	-	-
ENSMUSG00000015243	10363	1166	5.84	1285	7.06	210	0.93	303	1.74	728.547793324937	0.222218998964324	-2.16994592739591	0.240796236300208	-9.01154420325147	2.03175169401688e-19	6.77280010349017e-17	Down	4	53030787	53159895	-	Abca1	ATP-binding cassette%2C sub-family A (ABC1)%2C member 1 [Source:MGI Symbol%3BAcc:MGI:99607]	GO:0007189:adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0071397:cellular response to cholesterol;GO:0071345:cellular response to cytokine stimulus;GO:0035690:cellular response to drug;GO:0071222:cellular response to lipopolysaccharide;GO:0071300:cellular response to retinoic acid;GO:0033344:cholesterol efflux;GO:0042632:cholesterol homeostasis;GO:0008203:cholesterol metabolic process;GO:0030301:cholesterol transport;GO:0016197:endosomal transport;GO:0007186:G-protein coupled receptor signaling pathway;GO:0034380:high-density lipoprotein particle assembly;GO:0032367:intracellular cholesterol transport;GO:0006869:lipid transport;GO:0042158:lipoprotein biosynthetic process;GO:0042157:lipoprotein metabolic process;GO:0007040:lysosome organization;GO:0002790:peptide secretion;GO:0006911:phagocytosis, engulfment;GO:0033700:phospholipid efflux;GO:0055091:phospholipid homeostasis;GO:0045332:phospholipid translocation;GO:0015914:phospholipid transport;GO:0060155:platelet dense granule organization;GO:0010875:positive regulation of cholesterol efflux;GO:0090108:positive regulation of high-density lipoprotein particle assembly;GO:0006497:protein lipidation;GO:0009306:protein secretion;GO:0071806:protein transmembrane transport;GO:0032489:regulation of Cdc42 protein signal transduction;GO:0034616:response to laminar fluid shear stress;GO:0007584:response to nutrient;GO:0043691:reverse cholesterol transport;GO:0023061:signal release;	GO:0016323:basolateral plasma membrane;GO:0009986:cell surface;GO:0030139:endocytic vesicle;GO:0005768:endosome;GO:0009897:external side of plasma membrane;GO:0005794:Golgi apparatus;GO:0005887:integral component of plasma membrane;GO:0043231:intracellular membrane-bounded organelle;GO:0016020:membrane;GO:0045121:membrane raft;GO:0048471:perinuclear region of cytoplasm;GO:0045335:phagocytic vesicle;GO:0005886:plasma membrane;	GO:0034186:apolipoprotein A-I binding;GO:0034188:apolipoprotein A-I receptor activity;GO:0034185:apolipoprotein binding;GO:0005524:ATP binding;GO:0051117:ATPase binding;GO:0042626:ATPase activity, coupled to transmembrane movement of substances;GO:0008035:high-density lipoprotein particle binding;GO:0005319:lipid transporter activity;GO:0031210:phosphatidylcholine binding;GO:0090554:phosphatidylcholine-translocating ATPase activity;GO:0090556:phosphatidylserine-translocating ATPase activity;GO:0005548:phospholipid transporter activity;GO:0008320:protein transmembrane transporter activity;GO:0005102:receptor binding;GO:0031267:small GTPase binding;GO:0046623:sphingolipid-translocating ATPase activity;GO:0019905:syntaxin binding;	K05641	;ko02010 ABC transporters;ko04975 Fat digestion and absorption;ko04979 Cholesterol metabolism;
ENSMUSG00000020282	5433	221	2.11	207	2.17	800	6.78	547	6.00	440.310031865888	3.24506207593587	1.69824607631016	0.192105487664662	8.84017472355922	9.55690292013342e-19	3.11799041228353e-16	Ups	11	32159585	32172300	-	Rhbdf1	rhomboid 5 homolog 1 [Source:MGI Symbol%3BAcc:MGI:104328]	GO:0016477:cell migration;GO:0008283:cell proliferation;GO:0050709:negative regulation of protein secretion;GO:0006508:proteolysis;GO:0042058:regulation of epidermal growth factor receptor signaling pathway;GO:0061136:regulation of proteasomal protein catabolic process;GO:0050708:regulation of protein secretion;GO:0015031:protein transport;	GO:0005789:endoplasmic reticulum membrane;GO:0000139:Golgi membrane;GO:0016021:integral component of membrane;	GO:0019838:growth factor binding;GO:0004252:serine-type endopeptidase activity;	-	-
ENSMUSG00000027663	11435	275	1.25	305	1.52	871	3.50	845	4.40	576.996542492953	3.09219229866306	1.62863004102892	0.18453206363274	8.82572930127882	1.08748781543299e-18	3.47407045038529e-16	Ups	3	32388941	32420163	-	Zmat3	zinc finger matrin type 3 [Source:MGI Symbol%3BAcc:MGI:1195270]	GO:0006915:apoptotic process;GO:0006974:cellular response to DNA damage stimulus;GO:0030308:negative regulation of cell growth;GO:0043065:positive regulation of apoptotic process;GO:0015031:protein transport;	GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0005886:plasma membrane;	GO:0003723:RNA binding;GO:0008270:zinc ion binding;	K10137	;ko04115 p53 signaling pathway;
ENSMUSG00000022325	3795	992	13.57	815	12.22	2292	27.79	1936	30.38	1504.46320033544	2.43911979356611	1.28636061559193	0.148896652718017	8.63928498129546	5.65659158322338e-18	1.77016684361525e-15	Ups	15	34495450	34530794	+	Pop1	processing of precursor 1%2C ribonuclease P/MRP family%2C (S. cerevisiae) [Source:MGI Symbol%3BAcc:MGI:1914974]	GO:0090502:RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0001682:tRNA 5'-leader removal;GO:0016078:tRNA catabolic process;GO:0008033:tRNA processing;	GO:0005615:extracellular space;GO:0030681:multimeric ribonuclease P complex;GO:0005655:nucleolar ribonuclease P complex;GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0000172:ribonuclease MRP complex;	GO:0004526:ribonuclease P activity;GO:0033204:ribonuclease P RNA binding;GO:0003723:RNA binding;	K01164	;ko03008 Ribosome biogenesis in eukaryotes;ko03013 RNA transport;
ENSMUSG00000049871	7069	379	2.78	399	3.21	92	0.60	91	0.77	235.513125964239	0.245552518168979	-2.02589647727668	0.234571078394266	-8.63659958058243	5.7910922254586e-18	1.77601216370364e-15	Down	16	3762871	3794496	-	Nlrc3	NLR family%2C CARD domain containing 3 [Source:MGI Symbol%3BAcc:MGI:2444070]	GO:0007249:I-kappaB kinase/NF-kappaB signaling;GO:0035556:intracellular signal transduction;GO:1900016:negative regulation of cytokine production involved in inflammatory response;GO:0050680:negative regulation of epithelial cell proliferation;GO:0048147:negative regulation of fibroblast proliferation;GO:0043124:negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050728:negative regulation of inflammatory response;GO:0045824:negative regulation of innate immune response;GO:0032687:negative regulation of interferon-alpha production;GO:0032688:negative regulation of interferon-beta production;GO:0032691:negative regulation of interleukin-1 beta production;GO:0032695:negative regulation of interleukin-12 production;GO:0032715:negative regulation of interleukin-6 production;GO:0032088:negative regulation of NF-kappaB transcription factor activity;GO:1901223:negative regulation of NIK/NF-kappaB signaling;GO:1900226:negative regulation of NLRP3 inflammasome complex assembly;GO:0014067:negative regulation of phosphatidylinositol 3-kinase signaling;GO:0032720:negative regulation of tumor necrosis factor production;GO:0031396:regulation of protein ubiquitination;GO:0032496:response to lipopolysaccharide;GO:0042110:T cell activation;	GO:0034451:centriolar satellite;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0043231:intracellular membrane-bounded organelle;GO:0048471:perinuclear region of cytoplasm;	GO:0005524:ATP binding;GO:0036312:phosphatidylinositol 3-kinase regulatory subunit binding;	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000019373	3454	1884	28.32	1653	27.23	787	10.48	639	11.02	1216.12057381977	0.419210344449261	-1.25425377757899	0.145706810460432	-8.60806556409793	7.43037584936035e-18	2.2073405353778e-15	Down	11	59708621	59730664	-	Cops3	COP9 signalosome subunit 3 [Source:MGI Symbol%3BAcc:MGI:1349409]	GO:0001701:in utero embryonic development;GO:0000338:protein deneddylation;GO:0006511:ubiquitin-dependent protein catabolic process;	GO:0008180:COP9 signalosome;GO:0005829:cytosol;GO:0005654:nucleoplasm;	-	K12177	-
ENSMUSG00000075122	3703	382	5.36	422	6.49	1242	15.43	913	14.68	735.673563067587	2.76669944425848	1.46816592771035	0.170573786266141	8.60721896282246	7.48543810092903e-18	2.2073405353778e-15	Ups	16	38275923	38316697	+	Cd80	CD80 antigen [Source:MGI Symbol%3BAcc:MGI:101775]	GO:0031295:T cell costimulation;GO:0007166:cell surface receptor signaling pathway;GO:0071222:cellular response to lipopolysaccharide;GO:0006955:immune response;GO:0042130:negative regulation of T cell proliferation;GO:0046641:positive regulation of alpha-beta T cell proliferation;GO:0050731:positive regulation of peptidyl-tyrosine phosphorylation;GO:0042102:positive regulation of T cell proliferation;	GO:0016021:integral component of membrane;GO:0009986:cell surface;GO:0009897:external side of plasma membrane;GO:0098636:protein complex involved in cell adhesion;	GO:0015026:coreceptor activity;	K05412	;ko04514 Cell adhesion molecules;ko04620 Toll-like receptor signaling pathway;ko04672 Intestinal immune network for IgA production;ko04940 Type I diabetes mellitus;ko05320 Autoimmune thyroid disease;ko05322 Systemic lupus erythematosus;ko05323 Rheumatoid arthritis;ko05330 Allograft rejection;ko05332 Graft-versus-host disease;ko05416 Viral myocarditis;
ENSMUSG00000036469	7146	515	3.74	750	5.97	143	0.92	135	1.13	379.192675017442	0.228297855848166	-2.13101078491627	0.24826772381875	-8.58351924341174	9.2013904732932e-18	2.66215323617883e-15	Down	8	66070552	66924289	+	Marchf1	membrane associated ring-CH-type finger 1 [Source:MGI Symbol%3BAcc:MGI:1920175]	GO:0002495:antigen processing and presentation of peptide antigen via MHC class II;GO:0006955:immune response;GO:0000209:protein polyubiquitination;	GO:0005737:cytoplasm;GO:0031901:early endosome membrane;GO:0005789:endoplasmic reticulum membrane;GO:0005768:endosome;GO:0016021:integral component of membrane;GO:0031902:late endosome membrane;GO:0005765:lysosomal membrane;GO:0005764:lysosome;GO:0005886:plasma membrane;GO:0032588:trans-Golgi network membrane;	GO:0042287:MHC protein binding;GO:0061630:ubiquitin protein ligase activity;GO:0004842:ubiquitin-protein transferase activity;GO:0008270:zinc ion binding;	K10656	-
ENSMUSG00000024095	11677	38	0.17	39	0.19	229	0.90	209	1.07	129.657144364686	5.9341560816781	2.56904287344804	0.300620643771769	8.54579659339181	1.27652677976667e-17	3.62486326684114e-15	Ups	17	80336916	80369763	-	Hnrnpll	heterogeneous nuclear ribonucleoprotein L-like [Source:MGI Symbol%3BAcc:MGI:1919942]	GO:0006397:mRNA processing;GO:0033120:positive regulation of RNA splicing;GO:0043484:regulation of RNA splicing;	GO:0005634:nucleus;	GO:0003729:mRNA binding;	K13159	-
ENSMUSG00000111394	3887	1118	14.93	1318	19.30	3196	37.84	3029	46.41	2172.53652996412	2.66596790645434	1.41465941303084	0.166354805845973	8.50386861886437	1.83375056756387e-17	5.11249658236807e-15	Ups	9	59580097	59583983	+	Gm49759	predicted gene%2C 49759 [Source:MGI Symbol%3BAcc:MGI:6215263]	-	-	-	-	-
ENSMUSG00000026581	5911	4416	38.78	4808	46.29	2113	16.45	1465	14.76	3136.00428724117	0.399227120764671	-1.32471836403269	0.157189840641881	-8.42750624737093	3.53109434689675e-17	9.66889298487764e-15	Down	1	163889551	163911750	+	Sell	selectin%2C lymphocyte [Source:MGI Symbol%3BAcc:MGI:98279]	GO:0016339:calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0050901:leukocyte tethering or rolling;GO:0090023:positive regulation of neutrophil chemotaxis;GO:0042981:regulation of apoptotic process;GO:0033198:response to ATP;	GO:0009986:cell surface;GO:0009897:external side of plasma membrane;GO:0005887:integral component of plasma membrane;GO:0005886:plasma membrane;	GO:0005509:calcium ion binding;GO:0050839:cell adhesion molecule binding;GO:0051861:glycolipid binding;GO:0070492:oligosaccharide binding;GO:0002020:protease binding;	K06495	;ko04514 Cell adhesion molecules;
ENSMUSG00000015312	1589	362	11.83	261	9.35	1363	39.47	793	29.72	685.08840712939	3.55223919550336	1.82872873105395	0.219424915823203	8.33418905138103	7.80311594717048e-17	2.09917508655986e-14	Ups	10	80765907	80768038	+	Gadd45b	growth arrest and DNA-damage-inducible 45 beta [Source:MGI Symbol%3BAcc:MGI:107776]	GO:0000185:activation of MAPKKK activity;GO:0006915:apoptotic process;GO:0030154:cell differentiation;GO:0006469:negative regulation of protein kinase activity;GO:0043065:positive regulation of apoptotic process;GO:0046330:positive regulation of JNK cascade;GO:0043410:positive regulation of MAPK cascade;GO:1900745:positive regulation of p38MAPK cascade;GO:0051726:regulation of cell cycle;	GO:0005737:cytoplasm;GO:0005634:nucleus;	-	K04402	;ko04010 MAPK signaling pathway;ko04064 NF-kappa B signaling pathway;ko04068 FoxO signaling pathway;ko04110 Cell cycle;ko04115 p53 signaling pathway;ko04210 Apoptosis;ko04218 Cellular senescence;ko05169 Epstein-Barr virus infection;ko05200 Pathways in cancer;ko05202 Transcriptional misregulation in cancer;ko05210 Colorectal cancer;ko05212 Pancreatic cancer;ko05213 Endometrial cancer;ko05214 Glioma;ko05216 Thyroid cancer;ko05217 Basal cell carcinoma;ko05218 Melanoma;ko05220 Chronic myeloid leukemia;ko05222 Small cell lung cancer;ko05223 Non-small cell lung cancer;ko05224 Breast cancer;ko05225 Hepatocellular carcinoma;ko05226 Gastric cancer;
ENSMUSG00000024063	3212	3441	55.62	3282	58.15	1608	23.04	1379	25.57	2385.12966428219	0.462574892415411	-1.11224113321676	0.133683611953611	-8.31995124131381	8.79995057242385e-17	2.32652486340599e-14	Down	17	73225300	73248942	+	Lbh	limb-bud and heart [Source:MGI Symbol%3BAcc:MGI:1925139]	GO:0030879:mammary gland development;GO:0060644:mammary gland epithelial cell differentiation;GO:0033147:negative regulation of intracellular estrogen receptor signaling pathway;GO:2000737:negative regulation of stem cell differentiation;GO:0045892:negative regulation of transcription, DNA-templated;GO:2000103:positive regulation of mammary stem cell proliferation;GO:0045893:positive regulation of transcription, DNA-templated;GO:0010468:regulation of gene expression;GO:0043408:regulation of MAPK cascade;	GO:0005737:cytoplasm;GO:0005634:nucleus;GO:0032991:macromolecular complex;	-	-	-
ENSMUSG00000013089	4103	472	5.97	411	5.70	140	1.57	85	1.23	269.799107035768	0.26248036136253	-1.92971860972679	0.23207329111252	-8.31512579701028	9.16549970016236e-17	2.38209783732694e-14	Down	16	22200059	22258469	-	Etv5	ets variant 5 [Source:MGI Symbol%3BAcc:MGI:1096867]	GO:0030154:cell differentiation;GO:0034599:cellular response to oxidative stress;GO:0007626:locomotory behavior;GO:0048133:male germ-line stem cell asymmetric division;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0007274:neuromuscular synaptic transmission;GO:0060252:positive regulation of glial cell proliferation;GO:0045666:positive regulation of neuron differentiation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-templated;GO:0060762:regulation of branching involved in mammary gland duct morphogenesis;GO:0050807:regulation of synapse organization;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0071340:skeletal muscle acetylcholine-gated channel clustering;	GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0005886:plasma membrane;GO:0045202:synapse;	GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000977:RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000976:transcription regulatory region sequence-specific DNA binding;	K15593	;ko05202 Transcriptional misregulation in cancer;ko05215 Prostate cancer;
ENSMUSG00000044026	4642	135	1.51	161	1.97	507	5.03	555	7.12	343.443746321023	3.76734220996489	1.91354708775718	0.2315217441449	8.26508583383671	1.39594266360362e-16	3.56756413394965e-14	Ups	19	38384428	38394058	+	Slc35g1	solute carrier family 35%2C member G1 [Source:MGI Symbol%3BAcc:MGI:2444789]	GO:1990034:calcium ion export from cell;GO:0051480:cytosolic calcium ion homeostasis;	GO:0005789:endoplasmic reticulum membrane;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	-	-	-
ENSMUSG00000046169	7798	1388	9.24	1339	9.77	330	1.95	429	3.28	857.13070503337	0.294898550518649	-1.76170936358536	0.213207143942945	-8.26290025280203	1.4217504109535e-16	3.57395422976409e-14	Down	13	104424343	104633203	+	Adamts6	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif%2C 6 [Source:MGI Symbol%3BAcc:MGI:1347348]	GO:0035904:aorta development;GO:0003279:cardiac septum development;GO:0060976:coronary vasculature development;GO:0030198:extracellular matrix organization;GO:0001822:kidney development;	GO:0031012:extracellular matrix;GO:0005576:extracellular region;	GO:0046872:metal ion binding;GO:0004222:metalloendopeptidase activity;GO:0008237:metallopeptidase activity;	K08621	-
ENSMUSG00000075033	6436	1717	13.85	1814	16.04	762	5.45	669	6.19	1219.54234832341	0.421747868501969	-1.24554731768314	0.151169261853305	-8.23942184021396	1.73044809781569e-16	4.27978889224288e-14	Down	16	55660316	55715648	-	Nxpe3	neurexophilin and PC-esterase domain family%2C member 3 [Source:MGI Symbol%3BAcc:MGI:2686598]	-	GO:0005576:extracellular region;	-	-	-
ENSMUSG00000036902	6129	122	1.03	96	0.89	406	3.05	504	4.90	286.709430584055	4.42750291383938	2.1464932564476	0.260934682078941	8.22617077709212	1.93293372585952e-16	4.65720203241369e-14	Ups	8	86363217	86427553	-	Neto2	neuropilin (NRP) and tolloid (TLL)-like 2 [Source:MGI Symbol%3BAcc:MGI:1921763]	GO:2000312:regulation of kainate selective glutamate receptor activity;	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;GO:0014069:postsynaptic density;GO:0045202:synapse;	GO:0035255:ionotropic glutamate receptor binding;	-	-
ENSMUSG00002076550	322	12	1.93	6	1.06	122	17.43	183	33.85	83.4420525410659	18.1345730464102	4.18067087432417	0.508272794913643	8.22525013370916	1.94783927720988e-16	4.65720203241369e-14	Ups	16	84416695	84417016	-	7SK	7SK RNA [Source:RFAM%3BAcc:RF00100]	-	-	-	-	-
ENSMUSG00000006445	4674	8	0.09	10	0.12	188	1.85	100	1.27	75.4983259662987	16.3073424107467	4.0274497817049	0.489740461432219	8.22364108925541	1.97416285448604e-16	4.65720203241369e-14	Ups	4	141028551	141056695	+	Epha2	Eph receptor A2 [Source:MGI Symbol%3BAcc:MGI:95278]	GO:0090630:activation of GTPase activity;GO:0048320:axial mesoderm formation;GO:0007411:axon guidance;GO:0001568:blood vessel development;GO:0002043:blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0048514:blood vessel morphogenesis;GO:0046849:bone remodeling;GO:0060444:branching involved in mammary gland duct morphogenesis;GO:0046058:cAMP metabolic process;GO:0007155:cell adhesion;GO:0060326:cell chemotaxis;GO:0016477:cell migration;GO:0048870:cell motility;GO:0050830:defense response to Gram-positive bacterium;GO:0048013:ephrin receptor signaling pathway;GO:0006954:inflammatory response;GO:0008630:intrinsic apoptotic signaling pathway in response to DNA damage;GO:0030216:keratinocyte differentiation;GO:0070309:lens fiber cell morphogenesis;GO:0033598:mammary gland epithelial cell proliferation;GO:0016525:negative regulation of angiogenesis;GO:0032682:negative regulation of chemokine production;GO:0001818:negative regulation of cytokine production;GO:1901491:negative regulation of lymphangiogenesis;GO:0051898:negative regulation of protein kinase B signaling;GO:0021915:neural tube development;GO:0030182:neuron differentiation;GO:0060035:notochord cell development;GO:0014028:notochord formation;GO:0048570:notochord morphogenesis;GO:0001649:osteoblast differentiation;GO:0030316:osteoclast differentiation;GO:1904238:pericyte cell differentiation;GO:1903348:positive regulation of bicellular tight junction assembly;GO:0033674:positive regulation of kinase activity;GO:1903078:positive regulation of protein localization to plasma membrane;GO:0036342:post-anal tail morphogenesis;GO:0043491:protein kinase B signaling;GO:0072659:protein localization to plasma membrane;GO:0045765:regulation of angiogenesis;GO:0043535:regulation of blood vessel endothelial cell migration;GO:0033628:regulation of cell adhesion mediated by integrin;GO:0070372:regulation of ERK1 and ERK2 cascade;GO:0010591:regulation of lamellipodium assembly;GO:0070848:response to growth factor;GO:0001501:skeletal system development;GO:0007169:transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001570:vasculogenesis;	GO:0009986:cell surface;GO:0005925:focal adhesion;GO:0005887:integral component of plasma membrane;GO:0030027:lamellipodium;GO:0031258:lamellipodium membrane;GO:0031256:leading edge membrane;GO:0043005:neuron projection;GO:0005886:plasma membrane;GO:0043235:receptor complex;GO:0032587:ruffle membrane;GO:0070160:occluding junction;	GO:0005524:ATP binding;GO:0019838:growth factor binding;GO:0004714:transmembrane receptor protein tyrosine kinase activity;GO:0005005:transmembrane-ephrin receptor activity;	K05103	;ko04010 MAPK signaling pathway;ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04360 Axon guidance;
ENSMUSG00000022098	8870	230	1.35	237	1.52	856	4.44	554	3.72	464.743307550766	3.10212497175172	1.63325680774561	0.19888465472901	8.21208056484298	2.17388328488918e-16	5.05065549855919e-14	Ups	14	70711998	70757674	-	Bmp1	bone morphogenetic protein 1 [Source:MGI Symbol%3BAcc:MGI:88176]	GO:0001502:cartilage condensation;GO:0030154:cell differentiation;GO:0030199:collagen fibril organization;GO:0007275:multicellular organismal development;GO:0001503:ossification;GO:0061036:positive regulation of cartilage development;GO:0006508:proteolysis;GO:0001501:skeletal system development;GO:0051216:cartilage development;	GO:0005576:extracellular region;GO:0005615:extracellular space;GO:0005794:Golgi apparatus;GO:0031982:vesicle;	GO:0005509:calcium ion binding;GO:0005125:cytokine activity;GO:0008083:growth factor activity;GO:0042802:identical protein binding;GO:0004222:metalloendopeptidase activity;GO:0008237:metallopeptidase activity;GO:0008233:peptidase activity;GO:0004252:serine-type endopeptidase activity;GO:0008270:zinc ion binding;	K05502	-
ENSMUSG00000041538	5380	7011	67.65	6851	72.47	3461	29.60	2863	31.69	4957.92417051466	0.474058358739838	-1.07686342251062	0.13130943846751	-8.20095977165475	2.3847533157152e-16	5.45788169301148e-14	Down	17	34457877	34473388	+	H2-Ob	histocompatibility 2%2C O region beta locus [Source:MGI Symbol%3BAcc:MGI:95925]	GO:0002250:adaptive immune response;GO:0002504:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:0002587:negative regulation of antigen processing and presentation of peptide antigen via MHC class II;	GO:0010008:endosome membrane;GO:0016021:integral component of membrane;GO:0005765:lysosomal membrane;GO:0005764:lysosome;GO:0042613:MHC class II protein complex;	GO:0023026:MHC class II protein complex binding;GO:0032395:MHC class II receptor activity;	K06752	;ko04145 Phagosome;ko04514 Cell adhesion molecules;ko04612 Antigen processing and presentation;ko04640 Hematopoietic cell lineage;ko04658 Th1 and Th2 cell differentiation;ko04659 Th17 cell differentiation;ko04672 Intestinal immune network for IgA production;ko04940 Type I diabetes mellitus;ko05140 Leishmaniasis;ko05145 Toxoplasmosis;ko05150 Staphylococcus aureus infection;ko05152 Tuberculosis;ko05164 Influenza A;ko05166 Human T-cell leukemia virus 1 infection;ko05168 Herpes simplex virus 1 infection;ko05169 Epstein-Barr virus infection;ko05310 Asthma;ko05320 Autoimmune thyroid disease;ko05321 Inflammatory bowel disease;ko05322 Systemic lupus erythematosus;ko05323 Rheumatoid arthritis;ko05330 Allograft rejection;ko05332 Graft-versus-host disease;ko05416 Viral myocarditis;
ENSMUSG00000116274	1103	309	14.54	288	14.86	80	3.34	49	2.65	176.81962217884	0.222718111474722	-2.16670921178494	0.265339239696989	-8.16580771942841	3.19291511270255e-16	7.20002357914425e-14	Down	16	10864768	10866154	+	Gm18724	predicted gene%2C 18724 [Source:MGI Symbol%3BAcc:MGI:5010909]	GO:0019221:cytokine-mediated signaling pathway;GO:0002181:cytoplasmic translation;GO:0043547:positive regulation of GTPase activity;	GO:0005829:cytosol;GO:0005634:nucleus;	GO:0046872:metal ion binding;	-	-
ENSMUSG00000120679	2550	1856	37.79	1787	39.88	722	13.03	712	16.63	1248.39724058338	0.412215454583938	-1.27852950016633	0.157032055702786	-8.14183762954872	3.89323135951314e-16	8.57984623750043e-14	Down	17	8474829	8491359	-	-	novel transcript%2C antisense to Ccr6	-	-	-	-	-
ENSMUSG00000033955	6425	861	6.96	889	7.87	362	2.59	237	2.20	574.28870911444	0.352219355225428	-1.50545390428584	0.18491998958765	-8.14110960985246	3.91671603381394e-16	8.57984623750043e-14	Down	2	84878366	84903392	+	Tnks1bp1	tankyrase 1 binding protein 1 [Source:MGI Symbol%3BAcc:MGI:2446193]	GO:0071479:cellular response to ionizing radiation;GO:0006302:double-strand break repair;GO:0033138:positive regulation of peptidyl-serine phosphorylation;GO:0010800:positive regulation of peptidyl-threonine phosphorylation;GO:0031954:positive regulation of protein autophosphorylation;	GO:0015629:actin cytoskeleton;GO:0005912:adherens junction;GO:0030014:CCR4-NOT complex;GO:0005737:cytoplasm;GO:0000792:heterochromatin;GO:0005634:nucleus;GO:0005886:plasma membrane;	GO:0071532:ankyrin repeat binding;GO:0019899:enzyme binding;GO:0044877:macromolecular complex binding;	-	-
ENSMUSG00000020573	8426	887	5.47	729	4.92	266	1.45	267	1.89	526.800011767034	0.346074632733194	-1.53084489903924	0.188717088925226	-8.11185096038542	4.98544273543471e-16	1.07671519584727e-13	Down	12	32223472	32258658	-	Pik3cg	phosphatidylinositol-4%2C5-bisphosphate 3-kinase catalytic subunit gamma [Source:MGI Symbol%3BAcc:MGI:1353576]	GO:0001525:angiogenesis;GO:0006935:chemotaxis;GO:0006897:endocytosis;GO:0002376:immune system process;GO:0006954:inflammatory response;GO:0048015:phosphatidylinositol-mediated signaling;GO:0016477:cell migration;GO:0071320:cellular response to cAMP;GO:0007186:G-protein coupled receptor signaling pathway;GO:0097284:hepatocyte apoptotic process;GO:2000270:negative regulation of fibroblast apoptotic process;GO:0010897:negative regulation of triglyceride catabolic process;GO:0014065:phosphatidylinositol 3-kinase signaling;GO:0046854:phosphatidylinositol phosphorylation;GO:0036092:phosphatidylinositol-3-phosphate biosynthetic process;GO:0016310:phosphorylation;GO:0002675:positive regulation of acute inflammatory response;GO:0043085:positive regulation of catalytic activity;GO:0007204:positive regulation of cytosolic calcium ion concentration;GO:0010595:positive regulation of endothelial cell migration;GO:0043406:positive regulation of MAP kinase activity;GO:0051897:positive regulation of protein kinase B signaling;GO:0035022:positive regulation of Rac protein signal transduction;GO:0006468:protein phosphorylation;GO:1903169:regulation of calcium ion transmembrane transport;GO:0001932:regulation of protein phosphorylation;GO:0032252:secretory granule localization;GO:0003376:sphingosine-1-phosphate signaling pathway;	GO:0005737:cytoplasm;GO:0005886:plasma membrane;GO:0005829:cytosol;GO:0016020:membrane;GO:0005942:phosphatidylinositol 3-kinase complex;GO:0005943:phosphatidylinositol 3-kinase complex, class IA;GO:0005944:phosphatidylinositol 3-kinase complex, class IB;	GO:0016303:1-phosphatidylinositol-3-kinase activity;GO:0035005:1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0005524:ATP binding;GO:0052812:phosphatidylinositol-3,4-bisphosphate 5-kinase activity;GO:0046934:phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0046875:ephrin receptor binding;GO:0042802:identical protein binding;GO:0016301:kinase activity;GO:0052742:phosphatidylinositol kinase activity;	K00922	;ko00562 Inositol phosphate metabolism;ko01100 Metabolic pathways;ko01521 EGFR tyrosine kinase inhibitor resistance;ko01522 Endocrine resistance;ko01524 Platinum drug resistance;ko04012 ErbB signaling pathway;ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04024 cAMP signaling pathway;ko04062 Chemokine signaling pathway;ko04066 HIF-1 signaling pathway;ko04068 FoxO signaling pathway;ko04070 Phosphatidylinositol signaling system;ko04071 Sphingolipid signaling pathway;ko04072 Phospholipase D signaling pathway;ko04140 Autophagy - animal;ko04150 mTOR signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04210 Apoptosis;ko04211 Longevity regulating pathway;ko04212 Longevity regulating pathway - worm;ko04213 Longevity regulating pathway - multiple species;ko04218 Cellular senescence;ko04360 Axon guidance;ko04361 Axon regeneration;ko04370 VEGF signaling pathway;ko04380 Osteoclast differentiation;ko04510 Focal adhesion;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04611 Platelet activation;ko04613 Neutrophil extracellular trap formation;ko04620 Toll-like receptor signaling pathway;ko04625 C-type lectin receptor signaling pathway;ko04630 JAK-STAT signaling pathway;ko04650 Natural killer cell mediated cytotoxicity;ko04660 T cell receptor signaling pathway;ko04662 B cell receptor signaling pathway;ko04664 Fc epsilon RI signaling pathway;ko04666 Fc gamma R-mediated phagocytosis;ko04668 TNF signaling pathway;ko04670 Leukocyte transendothelial migration;ko04722 Neurotrophin signaling pathway;ko04725 Cholinergic synapse;ko04750 Inflammatory mediator regulation of TRP channels;ko04810 Regulation of actin cytoskeleton;ko04910 Insulin signaling pathway;ko04914 Progesterone-mediated oocyte maturation;ko04915 Estrogen signaling pathway;ko04917 Prolactin signaling pathway;ko04919 Thyroid hormone signaling pathway;ko04923 Regulation of lipolysis in adipocytes;ko04926 Relaxin signaling pathway;ko04929 GnRH secretion;ko04930 Type II diabetes mellitus;ko04931 Insulin resistance;ko04932 Non-alcoholic fatty liver disease;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko04935 Growth hormone synthesis, secretion and action;ko04960 Aldosterone-regulated sodium reabsorption;ko04973 Carbohydrate digestion and absorption;ko05010 Alzheimer disease;ko05017 Spinocerebellar ataxia;ko05020 Prion disease;ko05100 Bacterial invasion of epithelial cells;ko05131 Shigellosis;ko05132 Salmonella infection;ko05135 Yersinia infection;ko05142 Chagas disease;ko05146 Amoebiasis;ko05160 Hepatitis C;ko05161 Hepatitis B;ko05162 Measles;ko05163 Human cytomegalovirus infection;ko05164 Influenza A;ko05165 Human papillomavirus infection;ko05166 Human T-cell leukemia virus 1 infection;ko05167 Kaposi sarcoma-associated herpesvirus infection;ko05168 Herpes simplex virus 1 infection;ko05169 Epstein-Barr virus infection;ko05170 Human immunodeficiency virus 1 infection;ko05171 Coronavirus disease - COVID-19;ko05200 Pathways in cancer;ko05203 Viral carcinogenesis;ko05205 Proteoglycans in cancer;ko05206 MicroRNAs in cancer;ko05210 Colorectal cancer;ko05211 Renal cell carcinoma;ko05212 Pancreatic cancer;ko05213 Endometrial cancer;ko05214 Glioma;ko05215 Prostate cancer;ko05218 Melanoma;ko05220 Chronic myeloid leukemia;ko05221 Acute myeloid leukemia;ko05222 Small cell lung cancer;ko05223 Non-small cell lung cancer;ko05224 Breast cancer;ko05225 Hepatocellular carcinoma;ko05226 Gastric cancer;ko05230 Central carbon metabolism in cancer;ko05231 Choline metabolism in cancer;ko05235 PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05418 Fluid shear stress and atherosclerosis;
ENSMUSG00000024012	5615	1090	10.08	1047	10.61	484	3.97	356	3.78	728.984517784477	0.406656123684104	-1.29811875581618	0.16067227575924	-8.07929525913581	6.51421305985388e-16	1.3873464313861e-13	Down	17	29551046	29566908	-	Mtch1	mitochondrial carrier 1 [Source:MGI Symbol%3BAcc:MGI:1929261]	GO:0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006915:apoptotic process;GO:0043065:positive regulation of apoptotic process;GO:0045161:neuronal ion channel clustering;GO:0009966:regulation of signal transduction;	GO:0016021:integral component of membrane;GO:0016020:membrane;GO:0005741:mitochondrial outer membrane;GO:0005739:mitochondrion;	-	K17885	-
ENSMUSG00000020712	3752	31	0.43	24	0.36	196	2.40	156	2.48	101.885824774274	6.65167084557392	2.73371677938776	0.338432084016794	8.07759343305083	6.60574135909027e-16	1.38756764383959e-13	Ups	11	106167498	106179571	+	Tcam1	testicular cell adhesion molecule 1 [Source:MGI Symbol%3BAcc:MGI:1923120]	-	-	-	-	-
ENSMUSG00000097418	1433	2386	86.44	2399	95.27	6768	217.33	4498	186.94	3972.29843536041	2.42044979788517	1.27527517183017	0.158144619927882	8.06398075642237	7.38493889498763e-16	1.5302790948073e-13	Ups	16	84500055	84512133	+	Mir155hg	Mir155 host gene (non-protein coding) [Source:MGI Symbol%3BAcc:MGI:5477161]	-	-	-	-	-
ENSMUSG00000026728	4743	1826	19.99	1575	18.90	800	7.76	574	7.21	1167.81916314714	0.417978235694064	-1.25850027237478	0.156254726074248	-8.05415813008291	8.00277028826863e-16	1.63619306133748e-13	Down	2	13578738	13587637	+	Vim	vimentin [Source:MGI Symbol%3BAcc:MGI:98932]	GO:0014002:astrocyte development;GO:0060020:Bergmann glial cell differentiation;GO:0071346:cellular response to interferon-gamma;GO:0071222:cellular response to lipopolysaccharide;GO:0071225:cellular response to muramyl dipeptide;GO:0045109:intermediate filament organization;GO:0045103:intermediate filament-based process;GO:0070307:lens fiber cell development;GO:0010977:negative regulation of neuron projection development;GO:0032967:positive regulation of collagen biosynthetic process;GO:0010628:positive regulation of gene expression;GO:0060252:positive regulation of glial cell proliferation;GO:0045727:positive regulation of translation;GO:0050770:regulation of axonogenesis;GO:0043488:regulation of mRNA stability;GO:1900147:regulation of Schwann cell migration;GO:0060395:SMAD protein signal transduction;	GO:0030424:axon;GO:0044297:cell body;GO:0031252:cell leading edge;GO:0042995:cell projection;GO:0005737:cytoplasm;GO:0005856:cytoskeleton;GO:0005829:cytosol;GO:0005882:intermediate filament;GO:0045111:intermediate filament cytoskeleton;GO:0043005:neuron projection;GO:0016363:nuclear matrix;GO:0048471:perinuclear region of cytoplasm;GO:0005777:peroxisome;GO:0045335:phagocytic vesicle;GO:0005886:plasma membrane;GO:0005844:polysome;GO:0045098:type III intermediate filament;	GO:0003725:double-stranded RNA binding;GO:0042802:identical protein binding;GO:1990254:keratin filament binding;GO:0019900:kinase binding;GO:0019904:protein domain specific binding;GO:0019901:protein kinase binding;GO:0051721:protein phosphatase 2A binding;GO:0097110:scaffold protein binding;GO:0005200:structural constituent of cytoskeleton;GO:0005212:structural constituent of eye lens;	K07606	;ko05169 Epstein-Barr virus infection;ko05206 MicroRNAs in cancer;
ENSMUSG00000030643	9642	2168	11.67	2215	13.07	989	4.72	883	5.45	1537.89158117866	0.445022224805535	-1.16805070753625	0.145193365359288	-8.04479395216062	8.63906541215559e-16	1.74304511881571e-13	Down	7	92390811	92493743	+	Rab30	RAB30%2C member RAS oncogene family [Source:MGI Symbol%3BAcc:MGI:1923235]	GO:0007030:Golgi organization;GO:0032482:Rab protein signal transduction;	GO:0005801:cis-Golgi network;GO:0031985:Golgi cisterna;GO:0000139:Golgi membrane;GO:0005795:Golgi stack;GO:0043231:intracellular membrane-bounded organelle;GO:0005802:trans-Golgi network;	GO:0005525:GTP binding;GO:0003924:GTPase activity;	K07917	-
ENSMUSG00000028223	3879	810	10.84	747	10.96	320	3.80	266	4.08	525.262103586455	0.391444744055367	-1.35311942237349	0.168672787035702	-8.02215607006647	1.03905004652454e-15	2.06919394979316e-13	Down	4	15917240	15945507	-	Decr1	2%2C4-dienoyl CoA reductase 1%2C mitochondrial [Source:MGI Symbol%3BAcc:MGI:1914710]	GO:0006635:fatty acid beta-oxidation;	GO:1902494:catalytic complex;GO:0005829:cytosol;GO:0005739:mitochondrion;GO:0005654:nucleoplasm;	GO:0008670:2,4-dienoyl-CoA reductase (NADPH) activity;GO:0042802:identical protein binding;GO:0070402:NADPH binding;	K13236	-
ENSMUSG00000034659	3798	515	7.04	493	7.39	1407	17.05	996	15.62	845.847743885461	2.46071076008142	1.29907508871045	0.162135541669851	8.0122783402771	1.12602664665406e-15	2.21365289740941e-13	Ups	19	10848024	10859365	-	Tmem109	transmembrane protein 109 [Source:MGI Symbol%3BAcc:MGI:1915789]	GO:0071480:cellular response to gamma radiation;GO:0042771:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0060548:negative regulation of cell death;GO:0034765:regulation of ion transmembrane transport;	GO:0005783:endoplasmic reticulum;GO:0016021:integral component of membrane;GO:0031965:nuclear membrane;GO:0005640:nuclear outer membrane;GO:0033017:sarcoplasmic reticulum membrane;	GO:0005244:voltage-gated ion channel activity;	-	-
ENSMUSG00000076441	2414	994	21.38	834	19.66	350	6.67	191	4.71	576.334170622151	0.303109710900763	-1.72208802157096	0.215616726076885	-7.98680164059671	1.38484649746091e-15	2.68800458127412e-13	Down	2	31360219	31410684	+	Ass1	argininosuccinate synthetase 1 [Source:MGI Symbol%3BAcc:MGI:88090]	GO:0006526:arginine biosynthetic process;GO:0000053:argininosuccinate metabolic process;GO:0007623:circadian rhythm;GO:0000050:urea cycle;GO:0006953:acute-phase response;GO:0007568:aging;GO:0006531:aspartate metabolic process;GO:0071418:cellular response to amine stimulus;GO:0071230:cellular response to amino acid stimulus;GO:0071242:cellular response to ammonium ion;GO:0071320:cellular response to cAMP;GO:0071549:cellular response to dexamethasone stimulus;GO:0071377:cellular response to glucagon stimulus;GO:0071346:cellular response to interferon-gamma;GO:0071499:cellular response to laminar fluid shear stress;GO:0071222:cellular response to lipopolysaccharide;GO:0071400:cellular response to oleic acid;GO:0071356:cellular response to tumor necrosis factor;GO:0000052:citrulline metabolic process;GO:0060539:diaphragm development;GO:0001822:kidney development;GO:0001889:liver development;GO:0007494:midgut development;GO:1903038:negative regulation of leukocyte cell-cell adhesion;GO:0045429:positive regulation of nitric oxide biosynthetic process;GO:0042493:response to drug;GO:0032355:response to estradiol;GO:0051384:response to glucocorticoid;GO:0060416:response to growth hormone;GO:0010046:response to mycotoxin;GO:0007584:response to nutrient;GO:0010043:response to zinc ion;GO:0014075:response to amine;GO:0043200:response to amino acid;GO:0070542:response to fatty acid;GO:0032496:response to lipopolysaccharide;GO:0043434:response to peptide hormone;GO:0048545:response to steroid hormone;GO:0009636:response to toxic substance;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0070852:cell body fiber;GO:0005783:endoplasmic reticulum;GO:0005764:lysosome;GO:0005741:mitochondrial outer membrane;GO:0005739:mitochondrion;GO:0043209:myelin sheath;GO:0043005:neuron projection;GO:0043025:neuronal cell body;GO:0005634:nucleus;GO:0043204:perikaryon;	GO:0004055:argininosuccinate synthase activity;GO:0005524:ATP binding;GO:0016597:amino acid binding;GO:0042802:identical protein binding;GO:0015643:toxic substance binding;	K01940	;ko00220 Arginine biosynthesis;ko00250 Alanine, aspartate and glutamate metabolism;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko01230 Biosynthesis of amino acids;ko05418 Fluid shear stress and atherosclerosis;
ENSMUSG00000079227	8434	461	2.84	362	2.44	118	0.64	106	0.75	255.780847797311	0.284367008947893	-1.81417399557035	0.228112116910375	-7.95299267808353	1.8205910855313e-15	3.48961796319211e-13	Down	9	123921580	123947736	+	Ccr5	chemokine (C-C motif) receptor 5 [Source:MGI Symbol%3BAcc:MGI:107182]	GO:0006816:calcium ion transport;GO:0019722:calcium-mediated signaling;GO:0060326:cell chemotaxis;GO:0007267:cell-cell signaling;GO:0006952:defense response;GO:0007186:G-protein coupled receptor signaling pathway;GO:0006955:immune response;GO:0006954:inflammatory response;GO:0030517:negative regulation of axon extension;GO:0030336:negative regulation of cell migration;GO:2000110:negative regulation of macrophage apoptotic process;GO:2000178:negative regulation of neural precursor cell proliferation;GO:0070997:neuron death;GO:0060139:positive regulation of apoptotic process by virus;GO:0022409:positive regulation of cell-cell adhesion;GO:0007204:positive regulation of cytosolic calcium ion concentration;GO:0031622:positive regulation of fever generation;GO:0010628:positive regulation of gene expression;GO:0050729:positive regulation of inflammatory response;GO:0032731:positive regulation of interleukin-1 beta production;GO:0032755:positive regulation of interleukin-6 production;GO:0045666:positive regulation of neuron differentiation;GO:0032760:positive regulation of tumor necrosis factor production;GO:0014808:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0070723:response to cholesterol;	GO:0009986:cell surface;GO:0005737:cytoplasm;GO:0005768:endosome;GO:0009897:external side of plasma membrane;GO:0016021:integral component of membrane;	GO:0003779:actin binding;GO:0019957:C-C chemokine binding;GO:0016493:C-C chemokine receptor activity;GO:0071791:chemokine (C-C motif) ligand 5 binding;GO:0042802:identical protein binding;GO:0019901:protein kinase binding;	K04180	;ko04060 Cytokine-cytokine receptor interaction;ko04061 Viral protein interaction with cytokine and cytokine receptor;ko04062 Chemokine signaling pathway;ko04144 Endocytosis;ko05145 Toxoplasmosis;ko05163 Human cytomegalovirus infection;ko05167 Kaposi sarcoma-associated herpesvirus infection;ko05170 Human immunodeficiency virus 1 infection;ko05203 Viral carcinogenesis;
ENSMUSG00000032324	4274	783	9.51	617	8.22	2046	22.03	1415	19.72	1203.80228616213	2.55482736180744	1.35322580674836	0.170641074574562	7.93024663096025	2.1871109516186e-15	4.14039004100242e-13	Ups	9	56039009	56072761	-	Tspan3	tetraspanin 3 [Source:MGI Symbol%3BAcc:MGI:1928098]	-	GO:0005887:integral component of plasma membrane;	-	K17293	-
ENSMUSG00000034587	3904	43	0.57	58	0.85	291	3.43	204	3.11	148.431181800731	5.04424036882194	2.33463702480271	0.295053324691857	7.91259351929321	2.52081374405462e-15	4.71392170138214e-13	Ups	11	3402365	3429831	+	8430429K09Rik	RIKEN cDNA 8430429K09 gene [Source:MGI Symbol%3BAcc:MGI:1918773]	-	-	-	-	-
ENSMUSG00000003206	1154	1130	50.83	1288	63.51	3628	144.67	2407	124.22	2093.55136481869	2.56164784922326	1.35707216143354	0.171932437400419	7.89305486476067	2.94877901530338e-15	5.44778041212796e-13	Ups	17	56259640	56264022	+	Ebi3	Epstein-Barr virus induced gene 3 [Source:MGI Symbol%3BAcc:MGI:1354171]	GO:0019221:cytokine-mediated signaling pathway;GO:0033210:leptin-mediated signaling pathway;GO:0042098:T cell proliferation;	GO:0009897:external side of plasma membrane;GO:0005615:extracellular space;GO:0043235:receptor complex;	GO:0005125:cytokine activity;GO:0019955:cytokine binding;GO:0004896:cytokine receptor activity;GO:0045523:interleukin-27 receptor binding;GO:0017046:peptide hormone binding;	-	-
ENSMUSG00000111118	1786	1648	47.90	1088	34.67	489	12.60	397	13.24	883.418280914784	0.337997976316469	-1.5649134861519	0.199373440380418	-7.84915725568028	4.18842170071474e-15	7.64586409032855e-13	Down	19	12506119	12507904	-	Gm6545	predicted gene 6545 [Source:MGI Symbol%3BAcc:MGI:3643874]	GO:0006974:cellular response to DNA damage stimulus;GO:0006260:DNA replication;GO:0045071:negative regulation of viral genome replication;GO:0016540:protein autoprocessing;GO:0006508:proteolysis;GO:0031297:replication fork processing;	GO:0000785:chromatin;GO:0005737:cytoplasm;GO:0001650:fibrillar center;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0008233:peptidase activity;GO:0003697:single-stranded DNA binding;	-	-
ENSMUSG00000074272	5806	673	6.02	718	7.04	233	1.85	234	2.40	456.786709362285	0.351027288361111	-1.51034490694165	0.192742915137174	-7.83605927028108	4.64906489604105e-15	8.38691307245806e-13	Down	7	25161132	25177028	-	Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1 [Source:MGI Symbol%3BAcc:MGI:1347245]	GO:0097009:energy homeostasis;GO:0070348:negative regulation of brown fat cell proliferation;GO:2000252:negative regulation of feeding behavior;GO:0015721:bile acid and bile salt transport;GO:0001568:blood vessel development;GO:0045216:cell-cell junction organization;GO:0032869:cellular response to insulin stimulus;GO:0035726:common myeloid progenitor cell proliferation;GO:0038158:granulocyte colony-stimulating factor signaling pathway;GO:1901143:insulin catabolic process;GO:0038016:insulin receptor internalization;GO:0045779:negative regulation of bone resorption;GO:0001818:negative regulation of cytokine production;GO:0043318:negative regulation of cytotoxic T cell degranulation;GO:0045717:negative regulation of fatty acid biosynthetic process;GO:0030853:negative regulation of granulocyte differentiation;GO:2000346:negative regulation of hepatocyte proliferation;GO:0032692:negative regulation of interleukin-1 production;GO:0051055:negative regulation of lipid biosynthetic process;GO:0002859:negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0045671:negative regulation of osteoclast differentiation;GO:0090331:negative regulation of platelet aggregation;GO:0006469:negative regulation of protein kinase activity;GO:0001915:negative regulation of T cell mediated cytotoxicity;GO:0042130:negative regulation of T cell proliferation;GO:0050860:negative regulation of T cell receptor signaling pathway;GO:0043116:negative regulation of vascular permeability;GO:0043406:positive regulation of MAP kinase activity;GO:2001214:positive regulation of vasculogenesis;GO:0060312:regulation of blood vessel remodeling;GO:0001558:regulation of cell growth;GO:0045601:regulation of endothelial cell differentiation;GO:0010594:regulation of endothelial cell migration;GO:0042058:regulation of epidermal growth factor receptor signaling pathway;GO:0070372:regulation of ERK1 and ERK2 cascade;GO:1903385:regulation of homophilic cell adhesion;GO:0014066:regulation of phosphatidylinositol 3-kinase signaling;GO:1903670:regulation of sprouting angiogenesis;GO:0044319:wound healing, spreading of cells;	GO:0005912:adherens junction;GO:0016324:apical plasma membrane;GO:0009925:basal plasma membrane;GO:0030054:cell junction;GO:0009986:cell surface;GO:0005911:cell-cell junction;GO:0016021:integral component of membrane;GO:0016328:lateral plasma membrane;GO:0005886:plasma membrane;GO:0060170:ciliary membrane;GO:0009897:external side of plasma membrane;GO:0031528:microvillus membrane;GO:0030133:transport vesicle;	GO:0003779:actin binding;GO:0015125:bile acid transmembrane transporter activity;GO:0005516:calmodulin binding;GO:0031005:filamin binding;GO:0042802:identical protein binding;GO:0019900:kinase binding;GO:0046983:protein dimerization activity;GO:0042803:protein homodimerization activity;GO:0019901:protein kinase binding;GO:0019903:protein phosphatase binding;GO:0005130:granulocyte colony-stimulating factor receptor binding;GO:0035325:Toll-like receptor binding;GO:0001618:virus receptor activity;	K06499	-
ENSMUSG00000040164	2712	17	0.33	22	0.46	166	2.82	130	2.85	83.9334321817695	7.8568420487199	2.97394955725082	0.381126063159011	7.80306004947776	6.04237796163235e-15	1.07737004260082e-12	Ups	2	164005539	164013033	-	Kcns1	K+ voltage-gated channel%2C subfamily S%2C 1 [Source:MGI Symbol%3BAcc:MGI:1197019]	GO:0071805:potassium ion transmembrane transport;GO:0006813:potassium ion transport;GO:0051260:protein homooligomerization;GO:1902259:regulation of delayed rectifier potassium channel activity;	GO:0016021:integral component of membrane;GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;GO:0008076:voltage-gated potassium channel complex;	GO:0005251:delayed rectifier potassium channel activity;GO:0015459:potassium channel regulator activity;GO:0005249:voltage-gated potassium channel activity;	K04931	-
ENSMUSG00000085601	4695	0	0.00	0	0.00	628	6.15	348	4.41	241.452346562057	2708.48532095216	11.4032705565872	1.46499497232487	7.78382914071767	7.03617686142536e-15	1.23296937321321e-12	Ups	7	18832971	18852293	-	Meiosin	meiosis initiator [Source:MGI Symbol%3BAcc:MGI:3647482]	GO:0090427:activation of meiosis;GO:0071300:cellular response to retinoic acid;GO:0051321:meiotic cell cycle;GO:0048477:oogenesis;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0007283:spermatogenesis;	GO:0005634:nucleus;	GO:0003677:DNA binding;GO:0046983:protein dimerization activity;	-	-
ENSMUSG00000040405	2311	2468	55.44	1880	46.29	554	11.03	711	18.32	1377.06523716399	0.30940658449567	-1.6924241957146	0.21744810002851	-7.78311788188862	7.07586440868416e-15	1.23296937321321e-12	Down	11	46625907	46670405	+	Havcr1	hepatitis A virus cellular receptor 1 [Source:MGI Symbol%3BAcc:MGI:2159680]	GO:0006826:iron ion transport;GO:0006911:phagocytosis, engulfment;GO:0033005:positive regulation of mast cell activation;GO:0032496:response to lipopolysaccharide;GO:0009611:response to wounding;	GO:0009986:cell surface;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;GO:0005903:brush border;	GO:0070287:ferritin receptor activity;GO:0001786:phosphatidylserine binding;GO:0001618:virus receptor activity;	-	-
ENSMUSG00000064262	3700	4423	62.06	4998	76.87	1877	23.34	1856	29.87	3239.97167362992	0.414339941629959	-1.27111319464272	0.163741940367289	-7.7629054095212	8.30055208772041e-15	1.4243241512299e-12	Down	6	48624168	48637809	+	Gimap8	GTPase%2C IMAP family member 8 [Source:MGI Symbol%3BAcc:MGI:2685303]	GO:0070232:regulation of T cell apoptotic process;	GO:0005829:cytosol;GO:0005783:endoplasmic reticulum;GO:0005794:Golgi apparatus;GO:0005739:mitochondrion;	GO:0005525:GTP binding;	-	-
ENSMUSG00000003824	1968	288	7.60	221	6.39	936	21.89	587	17.76	502.02540463613	3.07988800427278	1.62287789032993	0.209079763910388	7.76200364864341	8.35980002678303e-15	1.4243241512299e-12	Ups	8	85598740	85614850	+	Syce2	synaptonemal complex central element protein 2 [Source:MGI Symbol%3BAcc:MGI:1919096]	GO:0051301:cell division;GO:0007130:synaptonemal complex assembly;	GO:0000801:central element;GO:0005694:chromosome;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0000795:synaptonemal complex;	-	K19535	-
ENSMUSG00000026113	10387	1262	6.31	1443	7.91	481	2.13	494	2.83	906.212484060092	0.377211119526556	-1.40655589011144	0.182644231727717	-7.70106932371295	1.34932258264777e-14	2.27368269036494e-12	Down	1	37338946	37449817	+	Inpp4a	inositol polyphosphate-4-phosphatase%2C type I [Source:MGI Symbol%3BAcc:MGI:1931123]	GO:0006798:polyphosphate catabolic process;GO:0043647:inositol phosphate metabolic process;GO:0006661:phosphatidylinositol biosynthetic process;GO:0007165:signal transduction;	GO:0005737:cytoplasm;GO:0031901:early endosome membrane;GO:0031965:nuclear membrane;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0005886:plasma membrane;GO:0014069:postsynaptic density;GO:0055038:recycling endosome membrane;GO:0005829:cytosol;	GO:0017161:inositol-1,3,4-trisphosphate 4-phosphatase activity;GO:0052828:inositol-3,4-bisphosphate 4-phosphatase activity;GO:0016316:phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity;GO:0034597:phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity;	K01109	;ko00562 Inositol phosphate metabolism;ko01100 Metabolic pathways;ko04070 Phosphatidylinositol signaling system;
ENSMUSG00000086290	2831	598	10.97	456	9.17	1548	25.16	1084	22.80	913.154763477973	2.58323134217545	1.36917685029447	0.17783629684345	7.6990854769078	1.37043478773711e-14	2.28415728643052e-12	Ups	4	132035932	132038762	+	Snhg12	small nucleolar RNA host gene 12 [Source:MGI Symbol%3BAcc:MGI:1916721]	-	-	-	-	-
ENSMUSG00000036908	3031	6763	115.84	6160	115.65	3323	50.45	2258	44.37	4526.39755478536	0.445110215094559	-1.16776548446529	0.151892657338626	-7.68809700828328	1.49339563735813e-14	2.46233641970426e-12	Down	19	3985186	3999340	+	Unc93b1	unc-93 homolog B1%2C TLR signaling regulator [Source:MGI Symbol%3BAcc:MGI:1859307]	GO:0002250:adaptive immune response;GO:0019882:antigen processing and presentation;GO:0019886:antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0000902:cell morphogenesis;GO:0051607:defense response to virus;GO:0045087:innate immune response;GO:0006886:intracellular protein transport;GO:0032735:positive regulation of interleukin-12 production;GO:0032755:positive regulation of interleukin-6 production;GO:0034138:toll-like receptor 3 signaling pathway;GO:0034154:toll-like receptor 7 signaling pathway;GO:0034162:toll-like receptor 9 signaling pathway;GO:0002224:toll-like receptor signaling pathway;	GO:0032009:early phagosome;GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0005768:endosome;GO:0016021:integral component of membrane;GO:0005764:lysosome;GO:0000139:Golgi membrane;	GO:0035325:Toll-like receptor binding;	-	-
ENSMUSG00000037822	15976	1820	5.91	1875	6.68	926	2.67	691	2.58	1302.88946654964	0.452414326312415	-1.14428347994375	0.149803952751694	-7.63853996456588	2.19698764263942e-14	3.58389452257797e-12	Down	5	65604187	65694527	-	Smim14	small integral membrane protein 14 [Source:MGI Symbol%3BAcc:MGI:1915802]	GO:0001835:blastocyst hatching;	GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0016021:integral component of membrane;	-	-	-
ENSMUSG00000117869	4666	1010	11.24	726	8.85	2185	21.55	1970	25.14	1471.396148044	2.50713621795986	1.32604038294344	0.174121171502395	7.6156183162666	2.6243212127422e-14	4.23593068170409e-12	Ups	18	35686424	35691369	+	Snhg4	small nucleolar RNA host gene 4 [Source:MGI Symbol%3BAcc:MGI:4937091]	-	-	-	-	-
ENSMUSG00000100150	2564	264	5.35	258	5.73	67	1.20	58	1.35	158.243155492925	0.249149931151253	-2.00491391953242	0.263503833144579	-7.60867079467631	2.76929125202628e-14	4.42336583943448e-12	Down	17	52293443	52471013	+	Gm19585	predicted gene%2C 19585 [Source:MGI Symbol%3BAcc:MGI:5011770]	-	-	-	-	-
ENSMUSG00000040658	1190	96	4.19	93	4.45	420	16.24	265	13.26	216.338315443307	3.72392194808674	1.89682283490308	0.249708362586774	7.59615262882487	3.05064695178716e-14	4.82253818130972e-12	Ups	17	46807637	46810550	+	Dnph1	2'-deoxynucleoside 5'-phosphate N-hydrolase 1 [Source:MGI Symbol%3BAcc:MGI:3039376]	GO:0019428:allantoin biosynthetic process;GO:0000255:allantoin metabolic process;GO:0009159:deoxyribonucleoside monophosphate catabolic process;GO:0046055:dGMP catabolic process;GO:0030855:epithelial cell differentiation;GO:0009116:nucleoside metabolic process;GO:0030307:positive regulation of cell growth;	GO:0005737:cytoplasm;GO:0005634:nucleus;	GO:0070694:deoxyribonucleoside 5'-monophosphate N-glycosidase activity;GO:0042802:identical protein binding;GO:0042803:protein homodimerization activity;	-	-
ENSMUSG00000036526	4866	2555	27.26	2613	30.56	1339	12.66	944	11.55	1825.96012141187	0.455512337910367	-1.13443796379958	0.151581005633321	-7.48403772002816	7.20732547653276e-14	1.12771581557981e-11	Down	5	140858745	140986337	-	Card11	caspase recruitment domain family%2C member 11 [Source:MGI Symbol%3BAcc:MGI:1916978]	GO:0030183:B cell differentiation;GO:0042100:B cell proliferation;GO:0048872:homeostasis of number of cells;GO:0007249:I-kappaB kinase/NF-kappaB signaling;GO:0046649:lymphocyte activation;GO:0030890:positive regulation of B cell proliferation;GO:0043123:positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032743:positive regulation of interleukin-2 production;GO:0051092:positive regulation of NF-kappaB transcription factor activity;GO:0050870:positive regulation of T cell activation;GO:0042102:positive regulation of T cell proliferation;GO:0050862:positive regulation of T cell receptor signaling pathway;GO:0051260:protein homooligomerization;GO:0042981:regulation of apoptotic process;GO:0045577:regulation of B cell differentiation;GO:0050776:regulation of immune response;GO:0045580:regulation of T cell differentiation;GO:0007165:signal transduction;GO:0042110:T cell activation;GO:0031295:T cell costimulation;GO:0045061:thymic T cell selection;GO:0038202:TORC1 signaling;	GO:0032449:CBM complex;GO:0005737:cytoplasm;GO:0001772:immunological synapse;GO:0045121:membrane raft;GO:0005886:plasma membrane;	GO:0050700:CARD domain binding;GO:0043621:protein self-association;	K07367	;ko04064 NF-kappa B signaling pathway;ko04660 T cell receptor signaling pathway;ko04662 B cell receptor signaling pathway;
ENSMUSG00000049313	11321	5426	24.88	4705	23.65	1582	6.43	1925	10.13	3354.87474357375	0.366872491816064	-1.44664935985212	0.193332399191244	-7.48270525738989	7.2808051221078e-14	1.12771581557981e-11	Down	9	41876016	42035593	-	Sorl1	sortilin-related receptor%2C LDLR class A repeats-containing [Source:MGI Symbol%3BAcc:MGI:1202296]	GO:0016477:cell migration;GO:0002024:diet induced thermogenesis;GO:0038020:insulin receptor recycling;GO:0008283:cell proliferation;GO:1902430:negative regulation of beta-amyloid formation;GO:1902960:negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:0030514:negative regulation of BMP signaling pathway;GO:0043407:negative regulation of MAP kinase activity;GO:1902963:negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process;GO:1902997:negative regulation of neurofibrillary tangle assembly;GO:0050768:negative regulation of neurogenesis;GO:1901215:negative regulation of neuron death;GO:0032091:negative regulation of protein binding;GO:0031333:negative regulation of protein complex assembly;GO:1902948:negative regulation of tau-protein kinase activity;GO:0010897:negative regulation of triglyceride catabolic process;GO:0007218:neuropeptide signaling pathway;GO:1904179:positive regulation of adipose tissue development;GO:1902771:positive regulation of choline O-acetyltransferase activity;GO:1902955:positive regulation of early endosome to recycling endosome transport;GO:2001137:positive regulation of endocytic recycling;GO:1902953:positive regulation of ER to Golgi vesicle-mediated transport;GO:1900168:positive regulation of glial cell line-derived neurotrophic factor secretion;GO:0046628:positive regulation of insulin receptor signaling pathway;GO:0045732:positive regulation of protein catabolic process;GO:0070863:positive regulation of protein exit from endoplasmic reticulum;GO:1902966:positive regulation of protein localization to early endosome;GO:0006892:post-Golgi vesicle-mediated transport;GO:0034067:protein localization to Golgi apparatus;GO:0051604:protein maturation;GO:0045053:protein retention in Golgi apparatus;GO:0006605:protein targeting;GO:0006622:protein targeting to lysosome;GO:0006898:receptor-mediated endocytosis;GO:0014910:regulation of smooth muscle cell migration;	GO:0009986:cell surface;GO:0005769:early endosome;GO:0031901:early endosome membrane;GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0005768:endosome;GO:0005615:extracellular space;GO:0005794:Golgi apparatus;GO:0031985:Golgi cisterna;GO:0000139:Golgi membrane;GO:0016021:integral component of membrane;GO:0016020:membrane;GO:0005771:multivesicular body;GO:0032585:multivesicular body membrane;GO:0043025:neuronal cell body;GO:0005641:nuclear envelope lumen;GO:0097356:perinucleolar compartment;GO:0005886:plasma membrane;GO:0055037:recycling endosome;GO:0055038:recycling endosome membrane;GO:0005802:trans-Golgi network;GO:0030658:transport vesicle membrane;	GO:0001540:beta-amyloid binding;GO:0030169:low-density lipoprotein particle binding;GO:0042923:neuropeptide binding;GO:0031267:small GTPase binding;GO:0004888:transmembrane signaling receptor activity;	-	-
ENSMUSG00000031762	588	7	0.62	16	1.55	142	11.11	107	10.84	68.1423632397137	11.1579389559205	3.47999865855289	0.46543663135131	7.47684738188602	7.61267355702655e-14	1.16732736323445e-11	Ups	8	94899292	94900196	+	Mt2	metallothionein 2 [Source:MGI Symbol%3BAcc:MGI:97172]	-	-	-	K14739	;ko04212 Longevity regulating pathway - worm;ko04978 Mineral absorption;
ENSMUSG00000052684	3189	117	1.90	143	2.55	434	6.26	366	6.84	265.177735900644	3.19309517780112	1.67495555650813	0.224660998368024	7.45547989493188	8.95413088964715e-14	1.35943210952326e-11	Ups	4	94937271	94940459	-	Jun	jun proto-oncogene [Source:MGI Symbol%3BAcc:MGI:96646]	GO:0007568:aging;GO:0001525:angiogenesis;GO:0031103:axon regeneration;GO:0009987:cellular process;	GO:0005829:cytosol;GO:0000791:euchromatin;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0035497:cAMP response element binding;GO:0003682:chromatin binding;GO:0003677:DNA binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;	K04448	;ko01522 Endocrine resistance;ko04010 MAPK signaling pathway;ko04012 ErbB signaling pathway;ko04013 MAPK signaling pathway - fly;ko04024 cAMP signaling pathway;ko04137 Mitophagy - animal;ko04210 Apoptosis;ko04214 Apoptosis - fly;ko04310 Wnt signaling pathway;ko04380 Osteoclast differentiation;ko04510 Focal adhesion;ko04530 Tight junction;ko04620 Toll-like receptor signaling pathway;ko04621 NOD-like receptor signaling pathway;ko04624 Toll and Imd signaling pathway;ko04625 C-type lectin receptor signaling pathway;ko04657 IL-17 signaling pathway;ko04658 Th1 and Th2 cell differentiation;ko04659 Th17 cell differentiation;ko04660 T cell receptor signaling pathway;ko04662 B cell receptor signaling pathway;ko04668 TNF signaling pathway;ko04722 Neurotrophin signaling pathway;ko04912 GnRH signaling pathway;ko04915 Estrogen signaling pathway;ko04921 Oxytocin signaling pathway;ko04926 Relaxin signaling pathway;ko04932 Non-alcoholic fatty liver disease;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05030 Cocaine addiction;ko05031 Amphetamine addiction;ko05120 Epithelial cell signaling in Helicobacter pylori infection;ko05130 Pathogenic Escherichia coli infection;ko05131 Shigellosis;ko05132 Salmonella infection;ko05133 Pertussis;ko05135 Yersinia infection;ko05140 Leishmaniasis;ko05142 Chagas disease;ko05161 Hepatitis B;ko05162 Measles;ko05166 Human T-cell leukemia virus 1 infection;ko05167 Kaposi sarcoma-associated herpesvirus infection;ko05169 Epstein-Barr virus infection;ko05170 Human immunodeficiency virus 1 infection;ko05171 Coronavirus disease - COVID-19;ko05200 Pathways in cancer;ko05203 Viral carcinogenesis;ko05210 Colorectal cancer;ko05211 Renal cell carcinoma;ko05224 Breast cancer;ko05231 Choline metabolism in cancer;ko05235 PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05321 Inflammatory bowel disease;ko05323 Rheumatoid arthritis;ko05418 Fluid shear stress and atherosclerosis;
ENSMUSG00000089774	10913	184	0.88	205	1.07	580	2.45	820	4.48	456.72276302986	3.826759991678	1.93612342029721	0.260402268537512	7.43512501319972	1.04469115849632e-13	1.57051904160614e-11	Ups	16	91855210	91884361	+	Slc5a3	solute carrier family 5 (inositol transporters)%2C member 3 [Source:MGI Symbol%3BAcc:MGI:1858226]	GO:0006020:inositol metabolic process;GO:0015798:myo-inositol transport;GO:0007422:peripheral nervous system development;GO:0043085:positive regulation of catalytic activity;GO:1903428:positive regulation of reactive oxygen species biosynthetic process;GO:0043576:regulation of respiratory gaseous exchange;GO:0032409:regulation of transporter activity;	GO:0016021:integral component of membrane;GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;GO:0008076:voltage-gated potassium channel complex;	GO:0005412:glucose:sodium symporter activity;GO:0015459:potassium channel regulator activity;GO:0044325:ion channel binding;	K14383	-
ENSMUSG00000041220	6431	544	4.39	459	4.06	158	1.13	163	1.51	324.667807722257	0.335823440902523	-1.57422515915225	0.212460443758816	-7.40949765189844	1.26778720668484e-13	1.88740281818499e-11	Down	3	129326004	129432144	+	Elovl6	ELOVL family member 6%2C elongation of long chain fatty acids (yeast) [Source:MGI Symbol%3BAcc:MGI:2156528]	GO:0030497:fatty acid elongation;GO:0034625:fatty acid elongation, monounsaturated fatty acid;GO:0034626:fatty acid elongation, polyunsaturated fatty acid;GO:0019367:fatty acid elongation, saturated fatty acid;GO:0042759:long-chain fatty acid biosynthetic process;GO:0035338:long-chain fatty-acyl-CoA biosynthetic process;GO:0030148:sphingolipid biosynthetic process;GO:0006636:unsaturated fatty acid biosynthetic process;GO:0042761:very long-chain fatty acid biosynthetic process;	GO:0005783:endoplasmic reticulum;GO:0009923:fatty acid elongase complex;GO:0030176:integral component of endoplasmic reticulum membrane;	GO:0016747:transferase activity, transferring acyl groups other than amino-acyl groups;GO:0009922:fatty acid elongase activity;	K10203	;ko00062 Fatty acid elongation;ko01040 Biosynthesis of unsaturated fatty acids;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko01212 Fatty acid metabolism;
ENSMUSG00000022075	10124	1739	8.92	1615	9.08	873	3.97	648	3.81	1194.71310771313	0.469389705033852	-1.09114189482322	0.1478155274439	-7.38178128977243	1.56185614764487e-13	2.30060483142237e-11	Down	14	70022439	70043085	-	Rhobtb2	Rho-related BTB domain containing 2 [Source:MGI Symbol%3BAcc:MGI:2180557]	GO:0007015:actin filament organization;GO:0030865:cortical cytoskeleton organization;GO:0043652:engulfment of apoptotic cell;GO:0007163:establishment or maintenance of cell polarity;GO:0032956:regulation of actin cytoskeleton organization;GO:0008360:regulation of cell shape;GO:0007264:small GTPase mediated signal transduction;	GO:0005938:cell cortex;GO:0042995:cell projection;GO:0031410:cytoplasmic vesicle;GO:0005856:cytoskeleton;GO:0043231:intracellular membrane-bounded organelle;GO:0005886:plasma membrane;	GO:0005525:GTP binding;GO:0003924:GTPase activity;GO:0019901:protein kinase binding;	K07868	;ko04120 Ubiquitin mediated proteolysis;
ENSMUSG00000030322	5280	1133	11.14	1483	15.98	430	3.75	444	5.01	860.09402139116	0.349133312821218	-1.51815007558179	0.205693651909076	-7.38063650234996	1.57534568474859e-13	2.30060483142237e-11	Down	6	115817658	115830332	-	Mbd4	methyl-CpG binding domain protein 4 [Source:MGI Symbol%3BAcc:MGI:1333850]	GO:0006974:cellular response to DNA damage stimulus;GO:0006306:DNA methylation;GO:0006281:DNA repair;GO:0008630:intrinsic apoptotic signaling pathway in response to DNA damage;GO:0007095:mitotic G2 DNA damage checkpoint;GO:0009314:response to radiation;	GO:0000785:chromatin;GO:0005737:cytoplasm;GO:0016607:nuclear speck;GO:0005634:nucleus;	GO:0003677:DNA binding;GO:0008263:pyrimidine-specific mismatch base pair DNA N-glycosylase activity;	K10801	;ko03410 Base excision repair;
ENSMUSG00000104960	860	407	24.57	339	22.43	1085	58.05	738	51.11	635.930253330857	2.52220123553445	1.33468338665961	0.180939983095751	7.37638726291534	1.62642482868804e-13	2.35279229463231e-11	Ups	3	123301194	123302053	-	Snhg8	small nucleolar RNA host gene 8 [Source:MGI Symbol%3BAcc:MGI:1917145]	-	-	-	-	-
ENSMUSG00000023921	3786	595	8.16	577	8.67	219	2.66	208	3.27	392.725171906224	0.38052831723838	-1.39392427816435	0.189229769941422	-7.36630541059078	1.75421687879846e-13	2.51394033827061e-11	Down	17	41245576	41272879	+	Mmut	methylmalonyl-Coenzyme A mutase [Source:MGI Symbol%3BAcc:MGI:97239]	GO:0050667:homocysteine metabolic process;GO:0043547:positive regulation of GTPase activity;GO:0009791:post-embryonic development;	GO:0005737:cytoplasm;GO:0005759:mitochondrial matrix;GO:0005739:mitochondrion;	GO:0031419:cobalamin binding;GO:0003924:GTPase activity;GO:0042802:identical protein binding;GO:0046872:metal ion binding;GO:0004494:methylmalonyl-CoA mutase activity;GO:0072341:modified amino acid binding;GO:0042803:protein homodimerization activity;	K01847	;ko00280 Valine, leucine and isoleucine degradation;ko00630 Glyoxylate and dicarboxylate metabolism;ko00640 Propanoate metabolism;ko00720 Carbon fixation pathways in prokaryotes;ko01100 Metabolic pathways;ko01120 Microbial metabolism in diverse environments;ko01200 Carbon metabolism;
ENSMUSG00000068923	5205	303	3.02	297	3.25	95	0.84	72	0.82	187.517396472989	0.28843379662306	-1.79368787564911	0.24388117388554	-7.35476153026449	1.91268272318941e-13	2.71565526642467e-11	Down	3	88652007	88682471	-	Syt11	synaptotagmin XI [Source:MGI Symbol%3BAcc:MGI:1859547]	GO:0006914:autophagy;GO:0017156:calcium ion-dependent exocytosis;GO:0071277:cellular response to calcium ion;GO:0051650:establishment of vesicle localization;GO:0007612:learning;GO:0007613:memory;GO:1900186:negative regulation of clathrin-mediated endocytosis;GO:0001818:negative regulation of cytokine production;GO:0033602:negative regulation of dopamine secretion;GO:0045806:negative regulation of endocytosis;GO:0032715:negative regulation of interleukin-6 production;GO:1903979:negative regulation of microglial cell activation;GO:0050765:negative regulation of phagocytosis;GO:1900243:negative regulation of synaptic vesicle endocytosis;GO:0032720:negative regulation of tumor necrosis factor production;GO:0001778:plasma membrane repair;GO:0017158:regulation of calcium ion-dependent exocytosis;GO:1900424:regulation of defense response to bacterium;GO:0014059:regulation of dopamine secretion;GO:0009611:response to wounding;GO:0006906:vesicle fusion;GO:0016192:vesicle-mediated transport;	GO:0030424:axon;GO:0044297:cell body;GO:0030665:clathrin-coated vesicle membrane;GO:0005737:cytoplasm;GO:0030425:dendrite;GO:0043197:dendritic spine;GO:0032009:early phagosome;GO:0060076:excitatory synapse;GO:0070382:exocytic vesicle;GO:0060077:inhibitory synapse;GO:0005887:integral component of plasma membrane;GO:0030285:integral component of synaptic vesicle membrane;GO:0005765:lysosomal membrane;GO:0005764:lysosome;GO:0043005:neuron projection;GO:0043204:perikaryon;GO:0048471:perinuclear region of cytoplasm;GO:0001891:phagocytic cup;GO:0045335:phagocytic vesicle;GO:0005886:plasma membrane;GO:0098794:postsynapse;GO:0014069:postsynaptic density;GO:0098793:presynapse;GO:0048787:presynaptic active zone membrane;GO:0055037:recycling endosome;GO:0055038:recycling endosome membrane;GO:0045202:synapse;GO:0043195:terminal bouton;GO:0005802:trans-Golgi network;GO:0031982:vesicle;	GO:0048487:beta-tubulin binding;GO:0005509:calcium ion binding;GO:0005544:calcium-dependent phospholipid binding;GO:0030276:clathrin binding;GO:0042802:identical protein binding;GO:0001786:phosphatidylserine binding;GO:0000149:SNARE binding;GO:0031369:translation initiation factor binding;GO:0031625:ubiquitin protein ligase binding;	-	-
ENSMUSG00000039997	6706	11845	91.70	11160	94.70	6281	43.10	4771	42.37	8354.10079284994	0.497453940009745	-1.00736514429802	0.137022701519855	-7.35181202183527	1.95537676653389e-13	2.75080250807621e-11	Down	1	173747973	173770238	-	Ifi203	interferon activated gene 203 [Source:MGI Symbol%3BAcc:MGI:96428]	GO:0002218:activation of innate immune response;GO:0035458:cellular response to interferon-beta;	GO:0005829:cytosol;GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0001227:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003690:double-stranded DNA binding;GO:0042802:identical protein binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	-	-
ENSMUSG00000022369	5481	1121	10.62	956	9.93	2235	18.76	1922	20.88	1553.072403924	2.08716501393985	1.06154466632506	0.144486983396887	7.34699168996511	2.02717466020578e-13	2.82588147632686e-11	Ups	15	55420804	55489819	+	Mtbp	Mdm2%2C transformed 3T3 cell double minute p53 binding protein [Source:MGI Symbol%3BAcc:MGI:2146005]	GO:0007049:cell cycle;GO:0008285:negative regulation of cell proliferation;GO:0045839:negative regulation of mitotic nuclear division;GO:0034501:protein localization to kinetochore;GO:0031396:regulation of protein ubiquitination;GO:0007089:traversing start control point of mitotic cell cycle;	GO:0000785:chromatin;GO:0000776:kinetochore;	-	-	-
ENSMUSG00000021057	6824	513	3.90	569	4.75	104	0.70	155	1.35	330.16701008841	0.253960189264828	-1.97732573667614	0.269325164914911	-7.34177861656872	2.10773832564814e-13	2.91171707076474e-11	Down	12	76371665	76380927	+	Akap5	A kinase (PRKA) anchor protein 5 [Source:MGI Symbol%3BAcc:MGI:2685104]	GO:0007193:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0036394:amylase secretion;GO:0043624:cellular protein complex disassembly;GO:0070073:clustering of voltage-gated calcium channels;GO:0045163:clustering of voltage-gated potassium channels;GO:0007194:negative regulation of adenylate cyclase activity;GO:0043271:negative regulation of ion transport;GO:0043267:negative regulation of potassium ion transport;GO:0045762:positive regulation of adenylate cyclase activity;GO:0070886:positive regulation of calcineurin-NFAT signaling cascade;GO:0010524:positive regulation of calcium ion transport into cytosol;GO:0050775:positive regulation of dendrite morphogenesis;GO:1900273:positive regulation of long-term synaptic potentiation;GO:0042307:positive regulation of protein import into nucleus;GO:1903078:positive regulation of protein localization to plasma membrane;GO:0001934:positive regulation of protein phosphorylation;GO:0043113:receptor clustering;GO:0010738:regulation of protein kinase A signaling;	GO:0032279:asymmetric synapse;GO:0016323:basolateral plasma membrane;GO:0005737:cytoplasm;GO:0009898:cytoplasmic side of plasma membrane;GO:0005856:cytoskeleton;GO:0030425:dendrite;GO:0032590:dendrite membrane;GO:0043198:dendritic shaft;GO:0043197:dendritic spine;GO:0032591:dendritic spine membrane;GO:0060076:excitatory synapse;GO:0031527:filopodium membrane;GO:0045121:membrane raft;GO:0043025:neuronal cell body;GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;GO:0014069:postsynaptic density;GO:0032991:macromolecular complex;	GO:0003779:actin binding;GO:0008179:adenylate cyclase binding;GO:0031698:beta-2 adrenergic receptor binding;GO:0045296:cadherin binding;GO:0005516:calmodulin binding;GO:0001664:G-protein coupled receptor binding;GO:0050811:GABA receptor binding;GO:0035254:glutamate receptor binding;GO:0019900:kinase binding;GO:0060090:binding, bridging;GO:0019904:protein domain specific binding;GO:0034237:protein kinase A regulatory subunit binding;GO:0019901:protein kinase binding;GO:0030346:protein phosphatase 2B binding;GO:0044877:macromolecular complex binding;GO:0097110:scaffold protein binding;GO:0017124:SH3 domain binding;	K16522	-
ENSMUSG00000106943	2373	93	2.03	100	2.40	442	8.57	262	6.58	221.596312613678	3.73356603613187	1.90055424842525	0.259228416019773	7.33158145857079	2.27452503197657e-13	3.11406846788649e-11	Ups	5	74253695	74256067	+	Dancr	differentiation antagonizing non-protein coding RNA [Source:MGI Symbol%3BAcc:MGI:1917286]	-	-	-	-	-
ENSMUSG00000029098	11521	2137	9.63	2020	9.98	913	3.65	901	4.66	1469.470706173	0.457182958749563	-1.12915646601934	0.154726850844906	-7.29774088888541	2.92639498117894e-13	3.9710920921591e-11	Down	5	35740384	35772696	+	Acox3	acyl-Coenzyme A oxidase 3%2C pristanoyl [Source:MGI Symbol%3BAcc:MGI:1933156]	GO:0006635:fatty acid beta-oxidation;GO:0033540:fatty acid beta-oxidation using acyl-CoA oxidase;GO:0055088:lipid homeostasis;	GO:0005739:mitochondrion;GO:0005782:peroxisomal matrix;GO:0005777:peroxisome;	GO:0003997:acyl-CoA oxidase activity;GO:0071949:FAD binding;GO:0005504:fatty acid binding;GO:0050660:flavin adenine dinucleotide binding;GO:0016402:pristanoyl-CoA oxidase activity;	K00232	;ko00071 Fatty acid degradation;ko00410 beta-Alanine metabolism;ko00592 alpha-Linolenic acid metabolism;ko00640 Propanoate metabolism;ko01040 Biosynthesis of unsaturated fatty acids;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko01200 Carbon metabolism;ko01212 Fatty acid metabolism;ko03320 PPAR signaling pathway;ko04024 cAMP signaling pathway;ko04146 Peroxisome;
ENSMUSG00000051457	4681	1647	18.27	1481	18.00	609	5.99	643	8.18	1077.50497353879	0.420790587658534	-1.24882566043354	0.171164002147263	-7.29607653926608	2.96280401492362e-13	3.98523129516129e-11	Down	7	126731404	126736995	-	Spn	sialophorin [Source:MGI Symbol%3BAcc:MGI:98384]	GO:0097190:apoptotic signaling pathway;GO:0007166:cell surface receptor signaling pathway;GO:0042742:defense response to bacterium;GO:0050901:leukocyte tethering or rolling;GO:0007162:negative regulation of cell adhesion;GO:0050868:negative regulation of T cell activation;GO:0042130:negative regulation of T cell proliferation;GO:0001808:negative regulation of type IV hypersensitivity;GO:0045060:negative thymic T cell selection;GO:0001934:positive regulation of protein phosphorylation;GO:2000406:positive regulation of T cell migration;GO:0042102:positive regulation of T cell proliferation;GO:0032760:positive regulation of tumor necrosis factor production;GO:0050688:regulation of defense response to virus;GO:0010468:regulation of gene expression;GO:0050776:regulation of immune response;GO:2000404:regulation of T cell migration;GO:0001562:response to protozoan;GO:0031295:T cell costimulation;GO:0050852:T cell receptor signaling pathway;GO:0002296:T-helper 1 cell lineage commitment;GO:0071594:thymocyte aggregation;GO:0006968:cellular defense response;GO:0006935:chemotaxis;GO:0007163:establishment or maintenance of cell polarity;GO:0006955:immune response;GO:0007165:signal transduction;	GO:0005604:basement membrane;GO:0009986:cell surface;GO:0032154:cleavage furrow;GO:0009897:external side of plasma membrane;GO:0005615:extracellular space;GO:0005887:integral component of plasma membrane;GO:0016020:membrane;GO:0005902:microvillus;GO:0016605:PML body;GO:0001931:uropod;GO:0070062:extracellular exosome;GO:0005886:plasma membrane;	GO:0031072:heat shock protein binding;GO:0030544:Hsp70 protein binding;GO:0019904:protein domain specific binding;GO:0004888:transmembrane signaling receptor activity;	K06477	;ko04514 Cell adhesion molecules;
ENSMUSG00000071068	4917	1315	13.88	1152	13.33	604	5.65	494	5.98	874.352775612641	0.462932016686744	-1.1111277510567	0.152635178158206	-7.2796308456824	3.3473486938774e-13	4.46332564103618e-11	Down	17	48606526	48619561	+	Treml2	triggering receptor expressed on myeloid cells-like 2 [Source:MGI Symbol%3BAcc:MGI:2147038]	GO:0042110:T cell activation;	GO:0009986:cell surface;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0038023:signaling receptor activity;	K14364	-
ENSMUSG00000058594	5115	1332	13.52	1377	15.32	683	6.14	519	6.04	959.650161053716	0.459102328664034	-1.12311234516439	0.154370372936737	-7.27543973495909	3.45293817163685e-13	4.5644270624034e-11	Down	2	11747384	11782393	-	Fbh1	F-box DNA helicase 1 [Source:MGI Symbol%3BAcc:MGI:1354699]	GO:0008219:cell death;GO:0006974:cellular response to DNA damage stimulus;GO:0000737:DNA catabolic process, endonucleolytic;GO:0000724:double-strand break repair via homologous recombination;GO:0035562:negative regulation of chromatin binding;GO:2000042:negative regulation of double-strand break repair via homologous recombination;GO:1902231:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0001934:positive regulation of protein phosphorylation;GO:0016567:protein ubiquitination;GO:0000725:recombinational repair;GO:0031297:replication fork processing;GO:0048478:replication fork protection;GO:0072429:response to intra-S DNA damage checkpoint signaling;	GO:0000785:chromatin;GO:0005634:nucleus;GO:0019005:SCF ubiquitin ligase complex;	GO:0043138:3'-5' DNA helicase activity;GO:0005524:ATP binding;GO:0003678:DNA helicase activity;GO:0015616:DNA translocase activity;GO:0003690:double-stranded DNA binding;GO:0003697:single-stranded DNA binding;	K10300	-
ENSMUSG00000058818	4471	523	6.07	499	6.35	166	1.71	175	2.33	334.88571711822	0.349862431145015	-1.51514034117197	0.208514570217274	-7.26635236853317	3.69324432709067e-13	4.84035970184687e-11	Down	7	3714408	3723390	-	Pirb	paired Ig-like receptor B [Source:MGI Symbol%3BAcc:MGI:894311]	GO:0001782:B cell homeostasis;GO:0019724:B cell mediated immunity;GO:0019221:cytokine-mediated signaling pathway;GO:0007611:learning or memory;GO:0043011:myeloid dendritic cell differentiation;GO:0051248:negative regulation of protein metabolic process;GO:1900454:positive regulation of long term synaptic depression;GO:0035307:positive regulation of protein dephosphorylation;GO:1900271:regulation of long-term synaptic potentiation;	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0001540:beta-amyloid binding;GO:0042803:protein homodimerization activity;GO:0044877:macromolecular complex binding;	K06512	;ko04380 Osteoclast differentiation;ko04662 B cell receptor signaling pathway;
ENSMUSG00000070031	3328	9898	154.40	8692	148.63	5056	69.91	3787	67.77	6722.76487994276	0.492720794173357	-1.0211577362518	0.140912749173719	-7.24673773125314	4.26929513157551e-13	5.54791284301516e-11	Down	1	85528099	85572758	+	Sp140	Sp140 nuclear body protein [Source:MGI Symbol%3BAcc:MGI:3702467]	GO:0006952:defense response;GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0001650:fibrillar center;GO:0005739:mitochondrion;GO:0005634:nucleus;GO:0016605:PML body;	GO:0003677:DNA binding;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046872:metal ion binding;	-	-
ENSMUSG00000041961	7893	63	0.41	61	0.44	239	1.39	228	1.72	148.645505474803	3.93764512972064	1.97733309786682	0.273474669757104	7.23040674890679	4.81549554038939e-13	6.19445632765348e-11	Ups	11	5226324	5394847	-	Znrf3	zinc and ring finger 3 [Source:MGI Symbol%3BAcc:MGI:3039616]	GO:0060173:limb development;GO:0090090:negative regulation of canonical Wnt signaling pathway;GO:2000051:negative regulation of non-canonical Wnt signaling pathway;GO:0030178:negative regulation of Wnt signaling pathway;GO:0016567:protein ubiquitination;GO:0060828:regulation of canonical Wnt signaling pathway;GO:2000095:regulation of Wnt signaling pathway, planar cell polarity pathway;GO:0072089:stem cell proliferation;GO:0006511:ubiquitin-dependent protein catabolic process;GO:0038018:Wnt receptor catabolic process;GO:0016055:Wnt signaling pathway;	GO:0005887:integral component of plasma membrane;	GO:0005109:frizzled binding;GO:0046872:metal ion binding;GO:0061630:ubiquitin protein ligase activity;GO:0004842:ubiquitin-protein transferase activity;	K16273	;ko04310 Wnt signaling pathway;
ENSMUSG00000089715	10609	1384	6.77	1582	8.49	619	2.68	588	3.30	1027.62879081421	0.424493344847363	-1.23618615932099	0.170991843739413	-7.22950365518549	4.8476246205714e-13	6.19445632765348e-11	Down	15	79708097	79718889	-	Cbx6	chromobox 6 [Source:MGI Symbol%3BAcc:MGI:3512628]	GO:0006325:chromatin organization;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;	GO:0000792:heterochromatin;GO:0005634:nucleus;GO:0031519:PcG protein complex;	GO:0003727:single-stranded RNA binding;	K11453	-
ENSMUSG00000031360	4720	1137	12.51	1139	13.73	569	5.55	441	5.56	806.289351762123	0.459761971549854	-1.12104095402776	0.155170607484013	-7.22457024693451	5.02688965325956e-13	6.3704401605853e-11	Down	X	161684234	161815504	+	Ctps2	cytidine 5'-triphosphate synthase 2 [Source:MGI Symbol%3BAcc:MGI:1933185]	GO:0044210:'de novo' CTP biosynthetic process;GO:0006241:CTP biosynthetic process;GO:0006541:glutamine metabolic process;GO:0019856:pyrimidine nucleobase biosynthetic process;	GO:0097268:cytoophidium;GO:0005737:cytoplasm;GO:0005739:mitochondrion;	GO:0005524:ATP binding;GO:0003883:CTP synthase activity;GO:0042802:identical protein binding;	K01937	;ko00240 Pyrimidine metabolism;ko01100 Metabolic pathways;ko01240 Biosynthesis of cofactors;
ENSMUSG00000089862	5018	424	4.39	481	5.45	171	1.57	108	1.28	289.492073884083	0.316705444451213	-1.65878642608378	0.229752440122545	-7.21988600077119	5.2031173854707e-13	6.53972147449243e-11	Down	6	8259288	8459470	+	Umad1	UMAP1-MVP12 associated (UMA) domain containing 1 [Source:MGI Symbol%3BAcc:MGI:3840148]	-	-	-	-	-
ENSMUSG00000031765	1246	131	5.46	104	4.75	413	15.25	302	14.43	236.057091949879	3.15197121613988	1.65625436013634	0.229951688579931	7.20261882121658	5.90669294102446e-13	7.36367719981049e-11	Ups	8	94905710	94906955	+	Mt1	metallothionein 1 [Source:MGI Symbol%3BAcc:MGI:97171]	-	-	-	K14739	;ko04212 Longevity regulating pathway - worm;ko04978 Mineral absorption;
ENSMUSG00000026923	14232	503	1.83	398	1.59	1110	3.59	891	3.73	721.74686940904	2.31056158100507	1.20824354067376	0.167806984458588	7.20019815964179	6.01251151184187e-13	7.43514931633736e-11	Ups	2	26347915	26406675	-	Notch1	notch 1 [Source:MGI Symbol%3BAcc:MGI:97363]	GO:0031100:organ regeneration;GO:0003180:aortic valve morphogenesis;GO:1902263:apoptotic process involved in embryonic digit morphogenesis;GO:0060842:arterial endothelial cell differentiation;	GO:0001669:acrosomal vesicle;GO:0005912:adherens junction;GO:0016324:apical plasma membrane;GO:0071944:cell periphery;	GO:0005509:calcium ion binding;GO:0003682:chromatin binding;GO:0031490:chromatin DNA binding;GO:0019899:enzyme binding;	K02599	;ko01522 Endocrine resistance;ko04320 Dorso-ventral axis formation;ko04330 Notch signaling pathway;ko04361 Axon regeneration;ko04658 Th1 and Th2 cell differentiation;ko04919 Thyroid hormone signaling pathway;ko05020 Prion disease;ko05165 Human papillomavirus infection;ko05200 Pathways in cancer;ko05206 MicroRNAs in cancer;ko05224 Breast cancer;
ENSMUSG00000018428	4390	296	3.50	210	2.72	689	7.22	615	8.34	452.218491065376	2.69690062468321	1.43130236216747	0.20099114143239	7.12122112430979	1.06975003830751e-12	1.30186881646091e-10	Ups	11	88721618	88755412	-	Akap1	A kinase (PRKA) anchor protein 1 [Source:MGI Symbol%3BAcc:MGI:104729]	GO:0006915:apoptotic process;GO:0010614:negative regulation of cardiac muscle hypertrophy;GO:0035308:negative regulation of protein dephosphorylation;GO:0042308:negative regulation of protein import into nucleus;	GO:0005783:endoplasmic reticulum;GO:0016021:integral component of membrane;GO:0005811:lipid particle;GO:0030061:mitochondrial crista;GO:0005741:mitochondrial outer membrane;GO:0005739:mitochondrion;GO:0031594:neuromuscular junction;GO:0045211:postsynaptic membrane;	GO:0048487:beta-tubulin binding;GO:0008017:microtubule binding;GO:0060090:binding, bridging;GO:0034237:protein kinase A regulatory subunit binding;GO:0019901:protein kinase binding;GO:0030346:protein phosphatase 2B binding;GO:0019903:protein phosphatase binding;GO:0003723:RNA binding;	K16518	-
ENSMUSG00000023942	4008	459	5.95	459	6.52	1237	14.20	841	12.50	741.823925843604	2.33115338418794	1.22104393339302	0.172160782500565	7.09246272965224	1.31746129109816e-12	1.5907048376141e-10	Ups	17	45896126	45910532	-	Slc29a1	solute carrier family 29 (nucleoside transporters)%2C member 1 [Source:MGI Symbol%3BAcc:MGI:1927073]	GO:0032238:adenosine transport;GO:0071333:cellular response to glucose stimulus;GO:0071456:cellular response to hypoxia;GO:0060079:regulation of excitatory postsynaptic membrane potential;GO:0007595:lactation;GO:0098810:neurotransmitter uptake involved in synaptic transmission;GO:0006836:neurotransmitter transport;GO:0001504:neurotransmitter uptake;GO:1901642:nucleoside transmembrane transport;GO:0015858:nucleoside transport;GO:0015860:purine nucleoside transmembrane transport;GO:0072531:pyrimidine-containing compound transmembrane transport;GO:0030431:sleep;GO:0015862:uridine transport;GO:0006139:nucleobase-containing compound metabolic process;	GO:0016324:apical plasma membrane;GO:0016323:basolateral plasma membrane;GO:0016021:integral component of membrane;GO:0005887:integral component of plasma membrane;GO:0005886:plasma membrane;GO:0098794:postsynapse;GO:0098793:presynapse;GO:0016020:membrane;	GO:0080122:AMP transmembrane transporter activity;GO:0005326:neurotransmitter transporter activity;GO:0005337:nucleoside transmembrane transporter activity;GO:0015211:purine nucleoside transmembrane transporter activity;GO:0015213:uridine transmembrane transporter activity;	K15014	;ko05034 Alcoholism;
ENSMUSG00000018008	7552	1882	12.94	1485	11.19	807	4.92	673	5.31	1187.80586207185	0.458224602105564	-1.12587317578459	0.159321137152083	-7.06669055914326	1.58672232104652e-12	1.9008437555412e-10	Down	15	78481247	78506219	+	Cyth4	cytohesin 4 [Source:MGI Symbol%3BAcc:MGI:2441702]	GO:0032012:regulation of ARF protein signal transduction;	GO:0034451:centriolar satellite;GO:0005829:cytosol;GO:0045171:intercellular bridge;GO:0005886:plasma membrane;	GO:0005085:guanyl-nucleotide exchange factor activity;GO:0008289:lipid binding;	K18441	;ko04072 Phospholipase D signaling pathway;ko04144 Endocytosis;ko05130 Pathogenic Escherichia coli infection;ko05131 Shigellosis;ko05132 Salmonella infection;
ENSMUSG00000093565	519	78	7.80	60	6.58	350	31.03	202	23.18	170.186026168025	4.10338533152597	2.03681463796892	0.289651037756542	7.03196043675461	2.03651556139512e-12	2.42076973786301e-10	Ups	17	24747205	24747723	+	Rab26os	RAB26%2C member RAS oncogene family%2C opposite strand [Source:MGI Symbol%3BAcc:MGI:1922864]	-	-	-	-	-
ENSMUSG00000039735	12376	54	0.23	52	0.24	205	0.76	293	1.41	154.605183780394	5.00137458526837	2.32232466184834	0.330774531091961	7.0208690317898	2.20492466487005e-12	2.60079344700903e-10	Ups	3	122332368	122413364	-	Fnbp1l	formin binding protein 1-like [Source:MGI Symbol%3BAcc:MGI:1925642]	GO:0006914:autophagy;GO:0006897:endocytosis;GO:0007165:signal transduction;GO:0060271:cilium morphogenesis;GO:0030154:cell differentiation;GO:0072583:clathrin-mediated endocytosis;GO:0010324:membrane invagination;GO:0007399:nervous system development;GO:0097320:membrane tubulation;GO:0051491:positive regulation of filopodium assembly;GO:0006900:membrane budding;GO:0016050:vesicle organization;GO:0030050:vesicle transport along actin filament;	GO:0005938:cell cortex;GO:0031410:cytoplasmic vesicle;GO:0005856:cytoskeleton;GO:0005886:plasma membrane;GO:0005737:cytoplasm;GO:0005829:cytosol;	GO:0008289:lipid binding;GO:0051020:GTPase binding;	-	-
ENSMUSG00000035000	6319	2347	19.28	1908	17.18	714	5.20	842	7.94	1428.84803593669	0.387089232697182	-1.36926191681132	0.195156928730352	-7.01620959972795	2.27967995051297e-12	2.66844369169205e-10	Down	2	62160417	62242575	-	Dpp4	dipeptidylpeptidase 4 [Source:MGI Symbol%3BAcc:MGI:94919]	GO:0002337:B-1a B cell differentiation;GO:0001662:behavioral fear response;GO:0007155:cell adhesion;GO:0043542:endothelial cell migration;GO:0051234:establishment of localization;GO:0035641:locomotory exploration behavior;GO:0010716:negative regulation of extracellular matrix disassembly;GO:0090024:negative regulation of neutrophil chemotaxis;GO:0008284:positive regulation of cell proliferation;GO:0002717:positive regulation of natural killer cell mediated immunity;GO:0006508:proteolysis;GO:0036343:psychomotor behavior;GO:0033632:regulation of cell-cell adhesion mediated by integrin;GO:0002709:regulation of T cell mediated immunity;GO:0001666:response to hypoxia;GO:0042110:T cell activation;GO:0031295:T cell costimulation;	GO:0016324:apical plasma membrane;GO:0009986:cell surface;GO:0030139:endocytic vesicle;GO:0005783:endoplasmic reticulum;GO:0005576:extracellular region;GO:0005794:Golgi apparatus;GO:0016021:integral component of membrane;GO:0046581:intercellular canaliculus;GO:0030027:lamellipodium;GO:0031258:lamellipodium membrane;GO:0045121:membrane raft;GO:0005886:plasma membrane;	GO:0004177:aminopeptidase activity;GO:0045499:chemorepellent activity;GO:0005518:collagen binding;GO:0008239:dipeptidyl-peptidase activity;GO:0042802:identical protein binding;GO:0042277:peptide binding;GO:0002020:protease binding;GO:0042803:protein homodimerization activity;GO:0004252:serine-type endopeptidase activity;GO:0008236:serine-type peptidase activity;GO:0005102:receptor binding;GO:0001618:virus receptor activity;	K01278	;ko04974 Protein digestion and absorption;
ENSMUSG00000056602	29729	190	0.33	181	0.35	37	0.06	39	0.08	109.374784670964	0.214313881161737	-2.22220279814107	0.317336066968439	-7.00267958625101	2.51112686863371e-12	2.91709237906283e-10	Down	5	150042110	150421218	+	Fry	FRY microtubule binding protein [Source:MGI Symbol%3BAcc:MGI:2443895]	GO:0000902:cell morphogenesis;GO:0031175:neuron projection development;	GO:0005938:cell cortex;GO:0005815:microtubule organizing center;GO:0030427:site of polarized growth;GO:0000922:spindle pole;	GO:0004857:enzyme inhibitor activity;	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000033538	3710	2869	40.15	2307	35.39	1350	16.74	963	15.46	1831.47974245078	0.462509841532074	-1.11244403049418	0.159293201072076	-6.98362530859573	2.8765863354778e-12	3.31650938858772e-10	Down	9	5308828	5336783	+	Casp4	caspase 4%2C apoptosis-related cysteine peptidase [Source:MGI Symbol%3BAcc:MGI:107700]	GO:0007015:actin filament organization;GO:0035234:ectopic germ cell programmed cell death;GO:0097194:execution phase of apoptosis;GO:0006954:inflammatory response;GO:0045087:innate immune response;GO:0097193:intrinsic apoptotic signaling pathway;GO:0070059:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0032731:positive regulation of interleukin-1 beta production;GO:1903265:positive regulation of tumor necrosis factor-mediated signaling pathway;GO:0016540:protein autoprocessing;GO:0070269:pyroptosis;GO:0042981:regulation of apoptotic process;GO:0050727:regulation of inflammatory response;	GO:0097169:AIM2 inflammasome complex;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0005576:extracellular region;GO:0072557:IPAF inflammasome complex;GO:0005739:mitochondrion;GO:0043005:neuron projection;GO:0043025:neuronal cell body;GO:0072559:NLRP3 inflammasome complex;GO:0005886:plasma membrane;GO:0032991:macromolecular complex;	GO:0050700:CARD domain binding;GO:0004197:cysteine-type endopeptidase activity;GO:0097199:cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0097110:scaffold protein binding;	K12808	-
ENSMUSG00000037922	7486	4390	30.44	4600	34.97	1936	11.90	1996	15.88	3185.49097975507	0.458724866950955	-1.12429897849774	0.161673621241087	-6.95412751855908	3.54750618651904e-12	4.05951193015545e-10	Down	3	135759124	136031827	-	Bank1	B cell scaffold protein with ankyrin repeats 1 [Source:MGI Symbol%3BAcc:MGI:2442120]	GO:0042113:B cell activation;GO:0050869:negative regulation of B cell activation;GO:0032715:negative regulation of interleukin-6 production;GO:0051898:negative regulation of protein kinase B signaling;GO:0045947:negative regulation of translational initiation;GO:0043410:positive regulation of MAPK cascade;GO:0050731:positive regulation of peptidyl-tyrosine phosphorylation;GO:0009617:response to bacterium;	GO:0048471:perinuclear region of cytoplasm;	GO:0043274:phospholipase binding;GO:0002020:protease binding;GO:0035591:signaling adaptor activity;GO:0005102:receptor binding;	-	-
ENSMUSG00000041460	9478	249	1.36	207	1.24	58	0.28	54	0.34	138.792098174662	0.256603097790332	-1.96238950770305	0.282267534702801	-6.9522324264788	3.59550366182216e-12	4.07003619462526e-10	Down	6	119213487	119329368	+	Cacna2d4	calcium channel%2C voltage-dependent%2C alpha 2/delta subunit 4 [Source:MGI Symbol%3BAcc:MGI:2442632]	GO:0070588:calcium ion transmembrane transport;GO:0050908:detection of light stimulus involved in visual perception;GO:0034765:regulation of ion transmembrane transport;	GO:0005891:voltage-gated calcium channel complex;	GO:0046872:metal ion binding;GO:0005245:voltage-gated calcium channel activity;	K04861	;ko04010 MAPK signaling pathway;ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko04921 Oxytocin signaling pathway;ko05410 Hypertrophic cardiomyopathy;ko05412 Arrhythmogenic right ventricular cardiomyopathy;ko05414 Dilated cardiomyopathy;
ENSMUSG00000092203	2597	1066	21.31	897	19.66	3317	58.77	1812	41.55	1743.32940054996	2.6687375499632	1.41615743437313	0.203714615236219	6.95167321564537	3.60978819922418e-12	4.07003619462526e-10	Ups	17	35167235	35171498	-	1110038B12Rik	RIKEN cDNA 1110038B12 gene [Source:MGI Symbol%3BAcc:MGI:1916013]	-	-	-	-	-
ENSMUSG00000041650	5210	479	4.77	408	4.46	181	1.60	131	1.50	292.962753995379	0.364435554892899	-1.45626437733527	0.209790687674467	-6.94151105312625	3.87927871912747e-12	4.34196057511684e-10	Down	14	122771736	123128512	+	Pcca	propionyl-Coenzyme A carboxylase%2C alpha polypeptide [Source:MGI Symbol%3BAcc:MGI:97499]	GO:0016042:lipid catabolic process;	GO:0005759:mitochondrial matrix;GO:0005739:mitochondrion;	GO:0005524:ATP binding;GO:0016421:CoA carboxylase activity;GO:0019899:enzyme binding;GO:0046872:metal ion binding;GO:0004658:propionyl-CoA carboxylase activity;	K01965	;ko00280 Valine, leucine and isoleucine degradation;ko00630 Glyoxylate and dicarboxylate metabolism;ko00640 Propanoate metabolism;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko01120 Microbial metabolism in diverse environments;ko01200 Carbon metabolism;
ENSMUSG00000040918	3838	205	2.77	167	2.48	503	6.03	429	6.66	325.364043259191	2.61198602982156	1.38514718066648	0.200293822050085	6.91557615950885	4.65965621294055e-12	5.17762089632104e-10	Ups	1	164076615	164092954	+	Slc19a2	solute carrier family 19 (thiamine transporter)%2C member 2 [Source:MGI Symbol%3BAcc:MGI:1928761]	GO:0071934:thiamine transmembrane transport;GO:0015888:thiamine transport;GO:0055085:transmembrane transport;	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0015234:thiamine transmembrane transporter activity;	K14610	;ko04977 Vitamin digestion and absorption;
ENSMUSG00000032122	6643	390	3.05	373	3.20	150	1.04	92	0.82	245.226744067491	0.326337042794801	-1.61556533662353	0.233654899062077	-6.91432254623647	4.70104460894923e-12	5.18603007436169e-10	Down	9	37138881	37167034	-	Slc37a2	solute carrier family 37 (glycerol-3-phosphate transporter)%2C member 2 [Source:MGI Symbol%3BAcc:MGI:1929693]	GO:0008643:carbohydrate transport;GO:0015760:glucose-6-phosphate transport;GO:0006072:glycerol-3-phosphate metabolic process;GO:0015794:glycerol-3-phosphate transport;GO:0006127:glycerophosphate shuttle;GO:0035435:phosphate ion transmembrane transport;	GO:0030176:integral component of endoplasmic reticulum membrane;	GO:0061513:glucose 6-phosphate:inorganic phosphate antiporter activity;GO:0015169:glycerol-3-phosphate transmembrane transporter activity;	K13783	-
ENSMUSG00000023034	3509	408	6.04	431	6.99	1287	16.88	787	13.36	719.22564100161	2.53167329926846	1.34009124365433	0.194009736964959	6.90734013982184	4.93824929899375e-12	5.40879391076929e-10	Ups	15	101152150	101172676	+	Nr4a1	nuclear receptor subfamily 4%2C group A%2C member 1 [Source:MGI Symbol%3BAcc:MGI:1352454]	GO:0006915:apoptotic process;GO:0002042:cell migration involved in sprouting angiogenesis;GO:0071376:cellular response to corticotropin-releasing hormone stimulus;GO:0044344:cellular response to fibroblast growth factor stimulus;GO:0071310:cellular response to organic substance;GO:0035924:cellular response to vascular endothelial growth factor stimulus;GO:0035767:endothelial cell chemotaxis;GO:0045444:fat cell differentiation;GO:0045786:negative regulation of cell cycle;GO:0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0014860:neurotransmitter secretion involved in regulation of skeletal muscle contraction;GO:0043065:positive regulation of apoptotic process;GO:0001938:positive regulation of endothelial cell proliferation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-templated;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0061469:regulation of type B pancreatic cell proliferation;GO:0001975:response to amphetamine;GO:0051602:response to electrical stimulus;GO:0010035:response to inorganic substance;GO:0032496:response to lipopolysaccharide;GO:0035914:skeletal muscle cell differentiation;	GO:0005829:cytosol;GO:0005739:mitochondrion;GO:0031965:nuclear membrane;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0098793:presynapse;GO:0005667:transcription factor complex;	GO:0003677:DNA binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0035259:glucocorticoid receptor binding;GO:0042802:identical protein binding;GO:0004879:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046982:protein heterodimerization activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043565:sequence-specific DNA binding;GO:0008270:zinc ion binding;	K04465	;ko04010 MAPK signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04925 Aldosterone synthesis and secretion;ko04927 Cortisol synthesis and secretion;ko04934 Cushing syndrome;
ENSMUSG00000035828	2427	227	4.86	214	5.02	672	12.74	444	10.90	385.30790397083	2.60548690624294	1.38155300458875	0.201243801748529	6.86507108584199	6.64581512164641e-12	7.07687007467542e-10	Ups	15	88746389	88749929	+	Pim3	proviral integration site 3 [Source:MGI Symbol%3BAcc:MGI:1355297]	GO:0006915:apoptotic process;GO:0007049:cell cycle;GO:0016572:histone phosphorylation;GO:0043066:negative regulation of apoptotic process;GO:0061179:negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0046777:protein autophosphorylation;GO:0006468:protein phosphorylation;GO:0007346:regulation of mitotic cell cycle;	GO:0005737:cytoplasm;GO:0005829:cytosol;	GO:0005524:ATP binding;GO:0004674:protein serine/threonine kinase activity;	K08807	-
ENSMUSG00000027834	7286	523	3.73	513	4.01	231	1.46	157	1.28	348.293576779314	0.386405882283814	-1.37181103829884	0.200236963065725	-6.85093809502377	7.33672624387196e-12	7.75871449817466e-10	Down	3	75464854	75550802	+	Serpini1	serine (or cysteine) peptidase inhibitor%2C clade I%2C member 1 [Source:MGI Symbol%3BAcc:MGI:1194506]	GO:0010951:negative regulation of endopeptidase activity;GO:0010976:positive regulation of neuron projection development;GO:0030155:regulation of cell adhesion;	GO:0060205:cytoplasmic membrane-bounded vesicle lumen;GO:0005615:extracellular space;GO:0043025:neuronal cell body;GO:0043204:perikaryon;GO:0034774:secretory granule lumen;	GO:0004867:serine-type endopeptidase inhibitor activity;	-	-
ENSMUSG00000020640	13579	5551	21.22	5678	23.80	2192	7.43	2447	10.73	3913.07669716127	0.435105600729559	-1.20056250735216	0.175422073797112	-6.84385084137527	7.7092192287742e-12	8.09679230507011e-10	Down	12	4642638	4763962	+	Itsn2	intersectin 2 [Source:MGI Symbol%3BAcc:MGI:1338049]	GO:0030154:cell differentiation;GO:0006897:endocytosis;GO:0016197:endosomal transport;GO:1903861:positive regulation of dendrite extension;	GO:0005813:centrosome;GO:0005905:coated pit;GO:0005737:cytoplasm;GO:0098793:presynapse;	GO:0005509:calcium ion binding;GO:0005085:guanyl-nucleotide exchange factor activity;GO:0060090:binding, bridging;	-	-
ENSMUSG00000036875	5878	661	5.84	606	5.87	1323	10.36	1336	13.54	984.078621563149	2.20257646558316	1.13919210523091	0.166699538282373	6.83380480215385	8.2691525363875e-12	8.62579489748067e-10	Ups	10	62782805	62809964	+	Dna2	DNA replication helicase/nuclease 2 [Source:MGI Symbol%3BAcc:MGI:2443732]	GO:0006284:base-excision repair;GO:0000729:DNA double-strand break processing;GO:0006260:DNA replication;GO:0000076:DNA replication checkpoint;GO:0033567:DNA replication, Okazaki fragment processing;GO:0043137:DNA replication, removal of RNA primer;GO:0043504:mitochondrial DNA repair;GO:0006264:mitochondrial DNA replication;GO:1902990:mitotic telomere maintenance via semi-conservative replication;GO:0090305:nucleic acid phosphodiester bond hydrolysis;GO:0045740:positive regulation of DNA replication;GO:0071932:replication fork reversal;GO:0000723:telomere maintenance;	GO:0000781:chromosome, telomeric region;GO:0005737:cytoplasm;GO:0042645:mitochondrial nucleoid;GO:0005634:nucleus;GO:0005760:gamma DNA polymerase complex;GO:0005739:mitochondrion;GO:0005654:nucleoplasm;	GO:0051539:4 iron, 4 sulfur cluster binding;GO:0043139:5'-3' DNA helicase activity;GO:0017108:5'-flap endonuclease activity;GO:0005524:ATP binding;GO:0003677:DNA binding;GO:0003678:DNA helicase activity;GO:0046872:metal ion binding;GO:0004518:nuclease activity;GO:0003723:RNA binding;GO:0017116:single-stranded DNA-dependent ATP-dependent DNA helicase activity;GO:0016890:site-specific endodeoxyribonuclease activity, specific for altered base;	K10742	;ko03030 DNA replication;
ENSMUSG00000030365	3110	2450	40.90	2835	51.88	1292	19.12	1117	21.39	1894.08624834064	0.473502134673762	-1.07855716512547	0.158078719946981	-6.82291180930118	8.92134289526203e-12	9.2432345916181e-10	Down	6	128864551	128875130	+	Clec2i	C-type lectin domain family 2%2C member i [Source:MGI Symbol%3BAcc:MGI:2136650]	GO:0001765:membrane raft assembly;GO:0045671:negative regulation of osteoclast differentiation;GO:2000522:positive regulation of immunological synapse formation;GO:0043113:receptor clustering;GO:0030833:regulation of actin filament polymerization;GO:0032663:regulation of interleukin-2 production;GO:0042129:regulation of T cell proliferation;GO:0050852:T cell receptor signaling pathway;	GO:0009986:cell surface;GO:0009897:external side of plasma membrane;GO:0016021:integral component of membrane;	GO:0030246:carbohydrate binding;GO:0046703:natural killer cell lectin-like receptor binding;GO:0004888:transmembrane signaling receptor activity;	K10072	-
ENSMUSG00000054920	7057	826	6.08	907	7.31	407	2.65	336	2.84	608.499578464601	0.444803375767071	-1.16876035767142	0.171495959739648	-6.81508975165215	9.420493357199e-12	9.69488893552278e-10	Down	5	65264882	65325531	+	Klhl5	kelch-like 5 [Source:MGI Symbol%3BAcc:MGI:1919028]	-	GO:0005737:cytoplasm;GO:0005856:cytoskeleton;GO:0005829:cytosol;	GO:0003779:actin binding;	K10442	-
ENSMUSG00000061825	2298	64	1.45	87	2.15	299	5.99	230	5.96	169.717305489097	3.61835126689615	1.85533247053788	0.272522936452986	6.80798649348899	9.89741536834108e-12	1.01177978172095e-09	Ups	8	105573700	105581115	+	Ces2c	carboxylesterase 2C [Source:MGI Symbol%3BAcc:MGI:2385905]	-	GO:0005783:endoplasmic reticulum;GO:0043231:intracellular membrane-bounded organelle;	GO:0047619:acylcarnitine hydrolase activity;GO:0047376:all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity;GO:0052689:carboxylic ester hydrolase activity;	K03927	;ko00983 Drug metabolism - other enzymes;
ENSMUSG00000044453	4175	466	5.79	456	6.22	200	2.20	131	1.87	306.242744332779	0.369969467251314	-1.43452188161257	0.211658466890064	-6.77753128750417	1.22246684576168e-11	1.24141103396752e-09	Down	7	30556815	30560989	-	Ffar1	free fatty acid receptor 1 [Source:MGI Symbol%3BAcc:MGI:2684079]	GO:0007186:G-protein coupled receptor signaling pathway;GO:0042593:glucose homeostasis;GO:0030073:insulin secretion;GO:0032691:negative regulation of interleukin-1 beta production;GO:0051928:positive regulation of calcium ion transport;GO:0010524:positive regulation of calcium ion transport into cytosol;GO:0007204:positive regulation of cytosolic calcium ion concentration;GO:0032024:positive regulation of insulin secretion;GO:0070542:response to fatty acid;	GO:0005887:integral component of plasma membrane;GO:0005886:plasma membrane;	GO:0045125:bioactive lipid receptor activity;GO:0005504:fatty acid binding;	K04325	;ko04911 Insulin secretion;
ENSMUSG00000097195	3634	1080	15.43	863	13.51	2164	27.40	1692	27.73	1439.67945425843	2.06223353337513	1.044207716976	0.154176909052923	6.7727892807707	1.26322878201427e-11	1.2743651410136e-09	Ups	9	88377321	88405615	-	Snhg5	small nucleolar RNA host gene 5 [Source:MGI Symbol%3BAcc:MGI:1919905]	-	-	-	-	-
ENSMUSG00000001473	2437	127	2.71	91	2.12	413	7.80	271	6.62	223.216725026588	3.23879505505476	1.69545717995441	0.252564672786979	6.71296251073248	1.9071212561498e-11	1.89894787933773e-09	Ups	18	67523787	67535819	+	Tubb6	tubulin%2C beta 6 class V [Source:MGI Symbol%3BAcc:MGI:1915201]	GO:0000226:microtubule cytoskeleton organization;GO:0000278:mitotic cell cycle;	GO:0005737:cytoplasm;GO:0005874:microtubule;	GO:0005525:GTP binding;GO:0005200:structural constituent of cytoskeleton;	K07375	;ko04145 Phagosome;ko04540 Gap junction;ko05010 Alzheimer disease;ko05012 Parkinson disease;ko05014 Amyotrophic lateral sclerosis;ko05016 Huntington disease;ko05020 Prion disease;ko05022 Pathways of neurodegeneration - multiple diseases;ko05130 Pathogenic Escherichia coli infection;ko05132 Salmonella infection;
ENSMUSG00000048528	3264	6	0.10	7	0.12	80	1.13	92	1.68	47.22531581194	13.9316163157409	3.80029074086892	0.567568139457526	6.69574360622354	2.1457766022478e-11	2.12279602702373e-09	Ups	7	132196607	132201366	-	Nkx1-2	NK1 homeobox 2 [Source:MGI Symbol%3BAcc:MGI:104806]	GO:0030154:cell differentiation;GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005634:nucleus;	GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K09309	-
ENSMUSG00000043004	4390	1399	16.54	1305	16.92	614	6.44	607	8.23	966.1877685964	0.473069784182069	-1.07987507862204	0.161470861527344	-6.68773962315904	2.26643916478847e-11	2.22779347133759e-09	Down	14	19922627	20027695	-	Gng2	guanine nucleotide binding protein (G protein)%2C gamma 2 [Source:MGI Symbol%3BAcc:MGI:102705]	GO:0007191:adenylate cyclase-activating dopamine receptor signaling pathway;GO:0071870:cellular response to catecholamine stimulus;GO:0071380:cellular response to prostaglandin E stimulus;GO:0007186:G-protein coupled receptor signaling pathway;	GO:0070062:extracellular exosome;GO:0031680:G-protein beta/gamma-subunit complex;GO:0005834:heterotrimeric G-protein complex;GO:0016020:membrane;GO:0005886:plasma membrane;	GO:0031681:G-protein beta-subunit binding;	K07826	;ko04014 Ras signaling pathway;ko04062 Chemokine signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04371 Apelin signaling pathway;ko04713 Circadian entrainment;ko04723 Retrograde endocannabinoid signaling;ko04724 Glutamatergic synapse;ko04725 Cholinergic synapse;ko04726 Serotonergic synapse;ko04727 GABAergic synapse;ko04728 Dopaminergic synapse;ko04926 Relaxin signaling pathway;ko05032 Morphine addiction;ko05034 Alcoholism;ko05163 Human cytomegalovirus infection;ko05167 Kaposi sarcoma-associated herpesvirus infection;ko05170 Human immunodeficiency virus 1 infection;ko05200 Pathways in cancer;
ENSMUSG00000074794	6266	420	3.48	458	4.16	132	0.97	151	1.44	285.847462554785	0.338447488700424	-1.56299608285438	0.233802191945835	-6.68512159721959	2.30732977983931e-11	2.25354107286981e-09	Down	13	81031503	81044161	+	Arrdc3	arrestin domain containing 3 [Source:MGI Symbol%3BAcc:MGI:2145242]	GO:0060613:fat pad development;GO:0071878:negative regulation of adrenergic receptor signaling pathway;GO:0031651:negative regulation of heat generation;GO:0090327:negative regulation of locomotion involved in locomotory behavior;GO:0051443:positive regulation of ubiquitin-protein transferase activity;GO:0015031:protein transport;GO:0043588:skin development;GO:0001659:temperature homeostasis;	GO:0005737:cytoplasm;GO:0005769:early endosome;GO:0005768:endosome;GO:0005764:lysosome;GO:0005886:plasma membrane;	GO:0031699:beta-3 adrenergic receptor binding;	-	-
ENSMUSG00000024579	2645	229	4.49	209	4.50	62	1.08	55	1.24	135.772460565837	0.278365576795772	-1.84494727901884	0.277796210733928	-6.64136949220634	3.10781860934621e-11	2.99718808526508e-09	Down	18	61829908	61840706	-	Pcyox1l	prenylcysteine oxidase 1 like [Source:MGI Symbol%3BAcc:MGI:3606062]	GO:0030327:prenylated protein catabolic process;GO:0030328:prenylcysteine catabolic process;	GO:0005576:extracellular region;	GO:0001735:prenylcysteine oxidase activity;	K05906	;ko00900 Terpenoid backbone biosynthesis;ko01110 Biosynthesis of secondary metabolites;
ENSMUSG00000001027	7041	831	6.13	983	7.94	430	2.81	327	2.77	631.420421357122	0.431074661073733	-1.21399033269026	0.183201497576193	-6.62653061657077	3.43668219717133e-11	3.29363030071407e-09	Down	11	106209418	106244114	-	Scn4a	sodium channel%2C voltage-gated%2C type IV%2C alpha [Source:MGI Symbol%3BAcc:MGI:98250]	GO:0006812:cation transport;GO:0015871:choline transport;GO:0086010:membrane depolarization during action potential;GO:0019228:neuronal action potential;GO:0006813:potassium ion transport;GO:0034765:regulation of ion transmembrane transport;GO:0100001:regulation of skeletal muscle contraction by action potential;GO:0035725:sodium ion transmembrane transport;GO:0006814:sodium ion transport;	GO:0030424:axon;GO:0005887:integral component of plasma membrane;GO:0001518:voltage-gated sodium channel complex;	GO:0005244:voltage-gated ion channel activity;GO:0005248:voltage-gated sodium channel activity;	K04837	-
ENSMUSG00000090958	4688	13	0.14	8	0.10	146	1.43	70	0.89	58.1530415023096	10.481903910372	3.38982888357369	0.512071595587016	6.61983385289657	3.59602815731274e-11	3.42493762510768e-09	Ups	7	98138490	98151388	+	Lrrc32	leucine rich repeat containing 32 [Source:MGI Symbol%3BAcc:MGI:93882]	GO:0046007:negative regulation of activated T cell proliferation;GO:0001818:negative regulation of cytokine production;GO:0010628:positive regulation of gene expression;GO:1901388:regulation of transforming growth factor beta activation;GO:1901398:regulation of transforming growth factor beta3 activation;GO:0007179:transforming growth factor beta receptor signaling pathway;	GO:0009986:cell surface;GO:0031012:extracellular matrix;GO:0005615:extracellular space;GO:0016021:integral component of membrane;GO:0005654:nucleoplasm;GO:0005886:plasma membrane;	GO:0050431:transforming growth factor beta binding;	-	-
ENSMUSG00000030541	2588	540	10.83	491	10.80	1166	20.73	878	20.20	762.925315592727	2.05344747327435	1.0380480439735	0.15764819355273	6.58458571950774	4.56155495698936e-11	4.29121985953833e-09	Ups	7	79744594	79765140	-	Idh2	isocitrate dehydrogenase 2 (NADP+)%2C mitochondrial [Source:MGI Symbol%3BAcc:MGI:96414]	GO:0006103:2-oxoglutarate metabolic process;GO:0006097:glyoxylate cycle;GO:0006102:isocitrate metabolic process;GO:0006741:NADP biosynthetic process;GO:0006739:NADP metabolic process;GO:1903976:negative regulation of glial cell migration;GO:0060253:negative regulation of glial cell proliferation;GO:0006099:tricarboxylic acid cycle;	GO:0005829:cytosol;GO:0005743:mitochondrial inner membrane;GO:0005739:mitochondrion;GO:0005777:peroxisome;	GO:0004450:isocitrate dehydrogenase (NADP+) activity;GO:0004448:isocitrate dehydrogenase activity;GO:0000287:magnesium ion binding;GO:0051287:NAD binding;	K00031	;ko00020 Citrate cycle (TCA cycle);ko00480 Glutathione metabolism;ko00720 Carbon fixation pathways in prokaryotes;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko01120 Microbial metabolism in diverse environments;ko01200 Carbon metabolism;ko01210 2-Oxocarboxylic acid metabolism;ko01230 Biosynthesis of amino acids;ko04146 Peroxisome;ko05230 Central carbon metabolism in cancer;
ENSMUSG00000021990	9102	800	4.56	830	5.19	285	1.44	329	2.15	553.15900832524	0.39647646494803	-1.33469286555459	0.202868609284723	-6.57909999117394	4.73304409339418e-11	4.42539622732355e-09	Down	14	60871450	61002005	+	Spata13	spermatogenesis associated 13 [Source:MGI Symbol%3BAcc:MGI:104838]	GO:0016477:cell migration;GO:0046847:filopodium assembly;GO:0035556:intracellular signal transduction;GO:0030032:lamellipodium assembly;GO:0030334:regulation of cell migration;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0030175:filopodium;GO:0030027:lamellipodium;GO:0005654:nucleoplasm;GO:0032587:ruffle membrane;	GO:0005085:guanyl-nucleotide exchange factor activity;GO:0042802:identical protein binding;	K05769	;ko04810 Regulation of actin cytoskeleton;
ENSMUSG00000040093	5253	509	5.03	447	4.84	198	1.73	175	1.98	325.959667694116	0.406926150553864	-1.29716109866816	0.197203912272637	-6.57776554085205	4.77570480704715e-11	4.43822166734915e-09	Down	2	118359238	118380168	-	Bmf	BCL2 modifying factor [Source:MGI Symbol%3BAcc:MGI:2176433]	GO:0043276:anoikis;GO:0009267:cellular response to starvation;GO:0034644:cellular response to UV;GO:2001234:negative regulation of apoptotic signaling pathway;GO:1904093:negative regulation of autophagic cell death;GO:0010507:negative regulation of autophagy;GO:0043065:positive regulation of apoptotic process;GO:2001235:positive regulation of apoptotic signaling pathway;GO:0031334:positive regulation of protein complex assembly;GO:0090200:positive regulation of release of cytochrome c from mitochondria;	GO:0001669:acrosomal vesicle;GO:0015629:actin cytoskeleton;GO:0005737:cytoplasm;GO:0016459:myosin complex;	-	K17460	;ko05206 MicroRNAs in cancer;
ENSMUSG00000004698	14838	1249	4.37	1383	5.30	619	1.92	571	2.29	941.37724978064	0.471213920784137	-1.0855459344338	0.165126747002008	-6.57401634891165	4.89758504245272e-11	4.52407042415482e-09	Down	12	34097579	34967094	-	Hdac9	histone deacetylase 9 [Source:MGI Symbol%3BAcc:MGI:1931221]	GO:0042113:B cell activation;GO:0030183:B cell differentiation;GO:0032869:cellular response to insulin stimulus;GO:0042632:cholesterol homeostasis;GO:0006325:chromatin organization;GO:0008340:determination of adult lifespan;GO:0006281:DNA repair;GO:0007507:heart development;GO:0016575:histone deacetylation;GO:0070932:histone H3 deacetylation;GO:0070933:histone H4 deacetylation;GO:1990678:histone H4-K16 deacetylation;GO:0006954:inflammatory response;GO:0001818:negative regulation of cytokine production;GO:0051005:negative regulation of lipoprotein lipase activity;GO:0045843:negative regulation of striated muscle tissue development;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0045892:negative regulation of transcription, DNA-templated;GO:0007399:nervous system development;GO:0034983:peptidyl-lysine deacetylation;GO:0090050:positive regulation of cell migration involved in sprouting angiogenesis;GO:0048742:regulation of skeletal muscle fiber development;GO:0051153:regulation of striated muscle cell differentiation;GO:0030182:neuron differentiation;GO:0001975:response to amphetamine;	GO:0005737:cytoplasm;GO:0000118:histone deacetylase complex;GO:0035097:histone methyltransferase complex;GO:0005634:nucleus;GO:0005667:transcription factor complex;GO:0005654:nucleoplasm;	GO:0004407:histone deacetylase activity;GO:0034739:histone deacetylase activity (H4-K16 specific);GO:0042826:histone deacetylase binding;GO:0033558:protein deacetylase activity;GO:0005080:protein kinase C binding;GO:0003714:transcription corepressor activity;GO:0032041:NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0046872:metal ion binding;GO:0008134:transcription factor binding;	K11409	;ko04613 Neutrophil extracellular trap formation;ko05034 Alcoholism;ko05203 Viral carcinogenesis;
ENSMUSG00000020009	2847	1548	28.23	1492	29.82	836	13.51	549	11.48	1082.83131144011	0.468847528202082	-1.09280926824614	0.166321905868052	-6.57044700481663	5.01644361418722e-11	4.60611654969741e-09	Down	10	19467697	19485977	+	Ifngr1	interferon gamma receptor 1 [Source:MGI Symbol%3BAcc:MGI:107655]	GO:0048143:astrocyte activation;GO:0019221:cytokine-mediated signaling pathway;GO:0051607:defense response to virus;GO:0001774:microglial cell activation;GO:1900222:negative regulation of beta-amyloid clearance;GO:1902004:positive regulation of beta-amyloid formation;GO:0010628:positive regulation of gene expression;GO:0032760:positive regulation of tumor necrosis factor production;	GO:0030425:dendrite;GO:0005783:endoplasmic reticulum;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;GO:0014069:postsynaptic density;GO:0031982:vesicle;	GO:0019955:cytokine binding;GO:0004896:cytokine receptor activity;	K05132	;ko04060 Cytokine-cytokine receptor interaction;ko04066 HIF-1 signaling pathway;ko04217 Necroptosis;ko04380 Osteoclast differentiation;ko04630 JAK-STAT signaling pathway;ko04650 Natural killer cell mediated cytotoxicity;ko04658 Th1 and Th2 cell differentiation;ko04659 Th17 cell differentiation;ko05140 Leishmaniasis;ko05142 Chagas disease;ko05145 Toxoplasmosis;ko05152 Tuberculosis;ko05164 Influenza A;ko05167 Kaposi sarcoma-associated herpesvirus infection;ko05168 Herpes simplex virus 1 infection;ko05200 Pathways in cancer;ko05235 PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05321 Inflammatory bowel disease;
ENSMUSG00000037126	7636	3572	24.28	3207	23.90	1913	11.53	1237	9.65	2427.76758790433	0.478026266276683	-1.06483820223364	0.16221583468494	-6.56432958164534	5.22674818628849e-11	4.77065218384212e-09	Down	19	46300526	46315595	-	Psd	pleckstrin and Sec7 domain containing [Source:MGI Symbol%3BAcc:MGI:1920978]	GO:0031175:neuron projection development;GO:0032012:regulation of ARF protein signal transduction;GO:0015854:guanine transport;GO:0030182:neuron differentiation;	GO:0032154:cleavage furrow;GO:0043197:dendritic spine;GO:0016021:integral component of membrane;GO:0014069:postsynaptic density;GO:0032587:ruffle membrane;	GO:0005085:guanyl-nucleotide exchange factor activity;GO:0005543:phospholipid binding;GO:0001409:guanine nucleotide transmembrane transporter activity;	K12494	;ko04144 Endocytosis;ko04361 Axon regeneration;
ENSMUSG00000036606	7720	365	2.45	438	3.23	954	5.69	799	6.16	637.652798316488	2.2642953580826	1.17906215774953	0.179761174499339	6.55904792029419	5.4152400077027e-11	4.91344912888244e-09	Ups	15	89039752	89064991	-	Plxnb2	plexin B2 [Source:MGI Symbol%3BAcc:MGI:2154239]	GO:0007420:brain development;GO:0007156:homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007162:negative regulation of cell adhesion;GO:0001843:neural tube closure;GO:0007405:neuroblast proliferation;GO:0050772:positive regulation of axonogenesis;GO:0010976:positive regulation of neuron projection development;GO:0045727:positive regulation of translation;GO:0030334:regulation of cell migration;GO:0008360:regulation of cell shape;GO:0043087:regulation of GTPase activity;GO:2001222:regulation of neuron migration;GO:0001932:regulation of protein phosphorylation;GO:0071526:semaphorin-plexin signaling pathway;GO:1902287:semaphorin-plexin signaling pathway involved in axon guidance;	GO:0005887:integral component of plasma membrane;GO:0002116:semaphorin receptor complex;	GO:0017154:semaphorin receptor activity;	K06821	;ko04360 Axon guidance;
ENSMUSG00000022346	2717	3524	67.33	2973	62.27	8241	139.57	5298	116.13	4945.76306507721	2.14405810495393	1.10034400402003	0.167815340738969	6.55687375882744	5.49474905478032e-11	4.95626364741185e-09	Ups	15	61857240	61862223	+	Myc	myelocytomatosis oncogene [Source:MGI Symbol%3BAcc:MGI:97250]	GO:0006879:cellular iron ion homeostasis;GO:0006974:cellular response to DNA damage stimulus;GO:0006338:chromatin remodeling;GO:0051276:chromosome organization;GO:0000165:MAPK cascade;GO:0051782:negative regulation of cell division;GO:0045656:negative regulation of monocyte differentiation;GO:0043280:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:2000573:positive regulation of DNA biosynthetic process;GO:0050679:positive regulation of epithelial cell proliferation;GO:0048146:positive regulation of fibroblast proliferation;GO:2001022:positive regulation of response to DNA damage stimulus;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-templated;GO:0032204:regulation of telomere maintenance;GO:0006355:regulation of transcription, DNA-templated;GO:0010332:response to gamma radiation;GO:0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006865:amino acid transport;GO:0001783:B cell apoptotic process;GO:0001658:branching involved in ureteric bud morphogenesis;	GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0030424:axon;GO:0000785:chromatin;GO:0005737:cytoplasm;GO:0000791:euchromatin;	GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0070888:E-box binding;GO:0046983:protein dimerization activity;GO:0044877:macromolecular complex binding;GO:0000987:core promoter proximal region sequence-specific DNA binding;GO:0001046:core promoter sequence-specific DNA binding;GO:0003677:DNA binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;	K04377	;ko04010 MAPK signaling pathway;ko04012 ErbB signaling pathway;ko04110 Cell cycle;ko04151 PI3K-Akt signaling pathway;ko04218 Cellular senescence;ko04310 Wnt signaling pathway;ko04350 TGF-beta signaling pathway;ko04390 Hippo signaling pathway;ko04391 Hippo signaling pathway - fly;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04630 JAK-STAT signaling pathway;ko04919 Thyroid hormone signaling pathway;ko05132 Salmonella infection;ko05160 Hepatitis C;ko05161 Hepatitis B;ko05163 Human cytomegalovirus infection;ko05166 Human T-cell leukemia virus 1 infection;ko05167 Kaposi sarcoma-associated herpesvirus infection;ko05169 Epstein-Barr virus infection;ko05200 Pathways in cancer;ko05202 Transcriptional misregulation in cancer;ko05205 Proteoglycans in cancer;ko05206 MicroRNAs in cancer;ko05210 Colorectal cancer;ko05213 Endometrial cancer;ko05216 Thyroid cancer;ko05219 Bladder cancer;ko05220 Chronic myeloid leukemia;ko05221 Acute myeloid leukemia;ko05222 Small cell lung cancer;ko05224 Breast cancer;ko05225 Hepatocellular carcinoma;ko05226 Gastric cancer;ko05230 Central carbon metabolism in cancer;
ENSMUSG00000001036	5228	37	0.37	43	0.47	172	1.51	159	1.81	103.364787861696	4.31371127690943	2.10892961801194	0.321943473136225	6.55062082007044	5.72983773402033e-11	5.13808957973496e-09	Ups	11	61408075	61470513	-	Epn2	epsin 2 [Source:MGI Symbol%3BAcc:MGI:1333766]	GO:0048568:embryonic organ development;GO:0006897:endocytosis;GO:0001701:in utero embryonic development;GO:1903671:negative regulation of sprouting angiogenesis;GO:0030948:negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0007219:Notch signaling pathway;GO:0045747:positive regulation of Notch signaling pathway;GO:0030100:regulation of endocytosis;	GO:0030128:clathrin coat of endocytic vesicle;GO:0030125:clathrin vesicle coat;GO:0005768:endosome;GO:0043231:intracellular membrane-bounded organelle;GO:0005886:plasma membrane;GO:0005829:cytosol;	GO:0030276:clathrin binding;GO:0005543:phospholipid binding;GO:0045296:cadherin binding;	K12471	;ko04144 Endocytosis;
ENSMUSG00000021880	2667	1695	32.99	1484	31.66	862	14.87	553	12.35	1122.59729778047	0.458152594254211	-1.12609990637256	0.171978900146484	-6.54789573263578	5.83534355866308e-11	5.20227663538021e-09	Down	14	51361365	51369644	+	Rnase6	ribonuclease%2C RNase A family%2C 6 [Source:MGI Symbol%3BAcc:MGI:1925666]	GO:0019731:antibacterial humoral response;GO:0050829:defense response to Gram-negative bacterium;GO:0050830:defense response to Gram-positive bacterium;GO:0045087:innate immune response;GO:0090501:RNA phosphodiester bond hydrolysis;	GO:0031410:cytoplasmic vesicle;GO:0005615:extracellular space;GO:0005764:lysosome;	GO:0004519:endonuclease activity;GO:0003676:nucleic acid binding;GO:0004540:ribonuclease activity;	K01172	-
ENSMUSG00000113035	3296	437	6.88	456	7.87	117	1.63	154	2.78	286.748040222683	0.320607129635589	-1.64112158650177	0.251476418938986	-6.52594622360973	6.75735632271147e-11	5.9550173478424e-09	Down	12	69511558	69522361	-	5830428M24Rik	RIKEN cDNA 5830428M24 gene [Source:MGI Symbol%3BAcc:MGI:1923312]	-	-	-	-	-
ENSMUSG00000005533	16791	136	0.42	130	0.44	352	0.96	383	1.36	252.314834630356	2.90632043122876	1.53919377353495	0.236156525480505	6.51768470256399	7.1400875680702e-11	6.22080129368116e-09	Ups	7	67602575	67883416	+	Igf1r	insulin-like growth factor I receptor [Source:MGI Symbol%3BAcc:MGI:96433]	GO:0030325:adrenal gland development;GO:0097242:beta-amyloid clearance;GO:0009887:organ morphogenesis;GO:0007409:axonogenesis;GO:0007568:aging;	GO:0035867:alphav-beta3 integrin-IGF-1-IGF1R complex;GO:0030424:axon;GO:0005901:caveola;GO:0005737:cytoplasm;	GO:0005524:ATP binding;GO:0001965:G-protein alpha-subunit binding;GO:0042802:identical protein binding;GO:0043559:insulin binding;	K05087	;ko01521 EGFR tyrosine kinase inhibitor resistance;ko01522 Endocrine resistance;ko04010 MAPK signaling pathway;ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04066 HIF-1 signaling pathway;ko04068 FoxO signaling pathway;ko04114 Oocyte meiosis;ko04140 Autophagy - animal;ko04144 Endocytosis;ko04150 mTOR signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04211 Longevity regulating pathway;ko04213 Longevity regulating pathway - multiple species;ko04510 Focal adhesion;ko04520 Adherens junction;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04730 Long-term depression;ko04913 Ovarian steroidogenesis;ko04914 Progesterone-mediated oocyte maturation;ko05200 Pathways in cancer;ko05202 Transcriptional misregulation in cancer;ko05205 Proteoglycans in cancer;ko05214 Glioma;ko05215 Prostate cancer;ko05218 Melanoma;ko05224 Breast cancer;ko05225 Hepatocellular carcinoma;
ENSMUSG00000038375	5257	253	2.50	244	2.64	76	0.67	71	0.80	157.851385111577	0.308544887735118	-1.69644770404763	0.260450233550123	-6.51351961149672	7.34100158491386e-11	6.34636754386485e-09	Down	2	155222979	155231770	+	Trp53inp2	transformation related protein 53 inducible nuclear protein 2 [Source:MGI Symbol%3BAcc:MGI:1915978]	GO:0000045:autophagosome assembly;GO:0016236:macroautophagy;GO:1903828:negative regulation of cellular protein localization;GO:0001649:osteoblast differentiation;GO:0010508:positive regulation of autophagy;GO:0045893:positive regulation of transcription, DNA-templated;GO:0001894:tissue homeostasis;GO:0006511:ubiquitin-dependent protein catabolic process;	GO:0005776:autophagosome;GO:0031410:cytoplasmic vesicle;GO:0005829:cytosol;GO:0005634:nucleus;GO:0016605:PML body;	GO:0043130:ubiquitin binding;	-	-
ENSMUSG00000049744	8818	1362	8.02	1329	8.58	565	2.95	602	4.07	950.794564076152	0.455572409206185	-1.13424771901505	0.174156469607505	-6.5128084048287	7.37585672526184e-11	6.34636754386485e-09	Down	2	43638836	44285965	+	Arhgap15	Rho GTPase activating protein 15 [Source:MGI Symbol%3BAcc:MGI:1923367]	GO:0008360:regulation of cell shape;GO:0043087:regulation of GTPase activity;GO:0007165:signal transduction;	GO:0005737:cytoplasm;GO:0016020:membrane;	GO:0005096:GTPase activator activity;	K01556	;ko00380 Tryptophan metabolism;ko01100 Metabolic pathways;ko01240 Biosynthesis of cofactors;
ENSMUSG00000097039	12364	253	1.06	315	1.45	739	2.75	589	2.84	472.515954396418	2.41890697761707	1.2743552895696	0.195688935512334	6.51214789550164	7.40837218176476e-11	6.34636754386485e-09	Ups	15	61909817	62249945	+	Pvt1	Pvt1 oncogene [Source:MGI Symbol%3BAcc:MGI:97824]	-	-	-	-	-
ENSMUSG00000028545	2105	616	15.19	574	15.52	274	5.99	150	4.24	393.380678674163	0.364651798686956	-1.45540858452272	0.223903012060261	-6.50017420994324	8.02270516586367e-11	6.79669397863831e-09	Down	4	111272203	111317495	+	Bend5	BEN domain containing 5 [Source:MGI Symbol%3BAcc:MGI:1914871]	GO:0045892:negative regulation of transcription, DNA-templated;	GO:0005794:Golgi apparatus;	GO:0003677:DNA binding;	-	-
ENSMUSG00000010914	3930	720	9.51	577	8.36	1367	16.01	1191	18.05	960.397143044488	2.05935798014972	1.04219463681626	0.16039930315225	6.49750102609245	8.16651358204937e-11	6.88051204764533e-09	Ups	2	102851420	102903858	-	Pdhx	pyruvate dehydrogenase complex%2C component X [Source:MGI Symbol%3BAcc:MGI:1351627]	-	GO:0005759:mitochondrial matrix;GO:0005739:mitochondrion;GO:0045254:pyruvate dehydrogenase complex;	GO:0016746:transferase activity, transferring acyl groups;GO:0034604:pyruvate dehydrogenase (NAD+) activity;	K13997	;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko01120 Microbial metabolism in diverse environments;
ENSMUSG00000044629	4003	204	2.65	260	3.70	62	0.71	57	0.85	143.162689393279	0.266503385121817	-1.90777423669675	0.294042848029624	-6.48808243247782	8.69357144988353e-11	7.28454779303356e-09	Down	11	17001586	17029371	+	Cnrip1	cannabinoid receptor interacting protein 1 [Source:MGI Symbol%3BAcc:MGI:1917505]	GO:2000272:negative regulation of receptor activity;GO:0010469:regulation of receptor activity;	GO:0005737:cytoplasm;GO:0043209:myelin sheath;GO:0005886:plasma membrane;	GO:0008022:protein C-terminus binding;GO:0031718:type 1 cannabinoid receptor binding;	-	-
ENSMUSG00000028028	6868	230	1.74	247	2.05	39	0.26	63	0.55	142.439471160472	0.226782567419101	-2.14061834907201	0.330883469302086	-6.46940251680478	9.83911808081855e-11	8.1114535834017e-09	Down	3	127463959	127574176	-	Alpk1	alpha-kinase 1 [Source:MGI Symbol%3BAcc:MGI:1918731]	GO:0060271:cilium morphogenesis;GO:0002753:cytoplasmic pattern recognition receptor signaling pathway;GO:0045087:innate immune response;GO:0043123:positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0009617:response to bacterium;	GO:0005813:centrosome;GO:0005829:cytosol;GO:0032391:photoreceptor connecting cilium;GO:0000922:spindle pole;	GO:0005524:ATP binding;GO:0048029:monosaccharide binding;GO:0004674:protein serine/threonine kinase activity;	K08868	-
ENSMUSG00000074364	5119	363	3.68	318	3.54	136	1.22	103	1.20	224.984688208412	0.364098680904885	-1.45759858084327	0.225472077403702	-6.46465228700352	1.01532001562932e-10	8.32562412816039e-09	Down	7	15680883	15701492	-	Ehd2	EH-domain containing 2 [Source:MGI Symbol%3BAcc:MGI:2154274]	GO:0060271:cilium morphogenesis;GO:0030866:cortical actin cytoskeleton organization;GO:0032456:endocytic recycling;GO:0006897:endocytosis;GO:0016197:endosomal transport;GO:0097320:membrane tubulation;GO:2001137:positive regulation of endocytic recycling;GO:1901741:positive regulation of myoblast fusion;GO:0072659:protein localization to plasma membrane;	GO:0005901:caveola;GO:0005829:cytosol;GO:0005769:early endosome;GO:0030139:endocytic vesicle;GO:0010008:endosome membrane;GO:0070062:extracellular exosome;GO:0019898:extrinsic component of membrane;GO:0045171:intercellular bridge;GO:0043231:intracellular membrane-bounded organelle;GO:0015630:microtubule cytoskeleton;GO:0005634:nucleus;GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;GO:0055038:recycling endosome membrane;GO:0016020:membrane;	GO:0005524:ATP binding;GO:0005509:calcium ion binding;GO:0005525:GTP binding;GO:0016787:hydrolase activity;GO:0042802:identical protein binding;GO:0003676:nucleic acid binding;GO:0019904:protein domain specific binding;	K12469	;ko04144 Endocytosis;
ENSMUSG00000096740	3281	330	5.22	236	4.09	97	1.36	61	1.11	176.050736587427	0.288575138751706	-1.79298108038254	0.278088726071593	-6.44751445235122	1.13699332943149e-10	9.27375303909703e-09	Down	19	8861096	8869991	+	Lbhd1	LBH domain containing 1 [Source:MGI Symbol%3BAcc:MGI:5516029]	GO:0045893:positive regulation of transcription, DNA-templated;	GO:0005634:nucleus;	-	-	-
ENSMUSG00000043263	3547	4383	64.15	3614	57.98	2130	27.63	1234	20.72	2769.65785435171	0.431047246316188	-1.21408208568814	0.188750827044114	-6.4321947866453	1.25774412619814e-10	1.02043642492711e-08	Down	1	173458483	173475494	+	Ifi209	interferon activated gene 209 [Source:MGI Symbol%3BAcc:MGI:2138243]	GO:0002218:activation of innate immune response;GO:0035458:cellular response to interferon-beta;	GO:0005829:cytosol;GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0001227:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003690:double-stranded DNA binding;GO:0042802:identical protein binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	-	-
ENSMUSG00000029772	18255	1440	4.10	1302	4.06	484	1.22	586	1.91	939.372332525285	0.412738969688104	-1.2766984347795	0.198784711550372	-6.42251823504039	1.34038187504495e-10	1.07126267224441e-08	Down	6	29768010	29912309	+	Ahcyl2	S-adenosylhomocysteine hydrolase-like 2 [Source:MGI Symbol%3BAcc:MGI:1921590]	GO:0006730:one-carbon metabolic process;GO:0033353:S-adenosylmethionine cycle;	GO:0005783:endoplasmic reticulum;GO:0005829:cytosol;GO:0043005:neuron projection;	GO:0004013:adenosylhomocysteinase activity;GO:0016787:hydrolase activity;	K01251	;ko00270 Cysteine and methionine metabolism;ko01100 Metabolic pathways;
ENSMUSG00000017861	4632	2744	30.75	2106	25.87	6401	63.59	4073	52.37	3780.6462780293	2.22377647948176	1.15301178439725	0.179529499824759	6.42240849288121	1.34134885268636e-10	1.07126267224441e-08	Ups	2	162896607	162926608	+	Mybl2	myeloblastosis oncogene-like 2 [Source:MGI Symbol%3BAcc:MGI:101785]	GO:0000278:mitotic cell cycle;GO:0090307:mitotic spindle assembly;GO:0043525:positive regulation of neuron apoptotic process;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0006355:regulation of transcription, DNA-templated;	GO:0031523:Myb complex;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K09421	-
ENSMUSG00000038564	6617	514	4.03	512	4.40	196	1.36	201	1.81	350.158737794187	0.40519516345924	-1.303311141121	0.203038532762497	-6.41903348782344	1.37142241549144e-10	1.08960576783139e-08	Down	5	31410621	31448460	-	Ift172	intraflagellar transport 172 [Source:MGI Symbol%3BAcc:MGI:2682064]	GO:0060348:bone development;GO:0007420:brain development;GO:0060271:cilium morphogenesis;GO:0031122:cytoplasmic microtubule organization;GO:0007368:determination of left/right symmetry;GO:0009953:dorsal/ventral pattern formation;GO:0048596:embryonic camera-type eye morphogenesis;GO:0008544:epidermis development;GO:0007507:heart development;GO:0001947:heart looping;GO:0061525:hindgut development;GO:0042073:intraciliary transport;GO:0070986:left/right axis specification;GO:0060173:limb development;GO:0050680:negative regulation of epithelial cell proliferation;GO:0045879:negative regulation of smoothened signaling pathway;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0001843:neural tube closure;GO:0021915:neural tube development;GO:0001841:neural tube formation;GO:0007219:Notch signaling pathway;GO:0045880:positive regulation of smoothened signaling pathway;GO:0016485:protein processing;GO:0008589:regulation of smoothened signaling pathway;GO:0060021:palate development;GO:0007224:smoothened signaling pathway;GO:0021522:spinal cord motor neuron differentiation;	GO:0005930:axoneme;GO:0036064:ciliary basal body;GO:0005929:cilium;GO:0030992:intraciliary transport particle B;GO:0031514:motile cilium;GO:0005634:nucleus;GO:0097598:sperm cytoplasmic droplet;GO:0097225:sperm midpiece;GO:0097228:sperm principal piece;	-	K19676	-
ENSMUSG00000020178	3062	125	2.12	169	3.14	616	9.26	336	6.54	307.006039861794	3.29151485443558	1.71875170857888	0.268196606125386	6.40855129902479	1.46908850409458e-10	1.16118572792713e-08	Ups	10	75152711	75170618	+	Adora2a	adenosine A2a receptor [Source:MGI Symbol%3BAcc:MGI:99402]	GO:0007189:adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0048143:astrocyte activation;GO:0042755:eating behavior;GO:0060079:regulation of excitatory postsynaptic membrane potential;GO:0001973:adenosine receptor signaling pathway;GO:0007186:G-protein coupled receptor signaling pathway;GO:0060080:regulation of inhibitory postsynaptic membrane potential;GO:0007626:locomotory behavior;GO:0051899:membrane depolarization;GO:0046636:negative regulation of alpha-beta T cell activation;GO:0008285:negative regulation of cell proliferation;GO:0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0050728:negative regulation of inflammatory response;GO:0040013:negative regulation of locomotion;GO:0043524:negative regulation of neuron apoptotic process;GO:0006469:negative regulation of protein kinase activity;GO:0043116:negative regulation of vascular permeability;GO:0048812:neuron projection morphogenesis;GO:0014057:positive regulation of acetylcholine secretion, neurotransmission;GO:2001235:positive regulation of apoptotic signaling pathway;GO:0045938:positive regulation of circadian sleep/wake cycle, sleep;GO:0014049:positive regulation of glutamate secretion;GO:1900273:positive regulation of long-term synaptic potentiation;GO:0050714:positive regulation of protein secretion;GO:0035815:positive regulation of renal sodium excretion;GO:0032230:positive regulation of synaptic transmission, GABAergic;GO:0051968:positive regulation of synaptic transmission, glutamatergic;GO:0035810:positive regulation of urine volume;GO:0060134:prepulse inhibition;GO:0007205:protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0051924:regulation of calcium ion transport;GO:0051881:regulation of mitochondrial membrane potential;GO:0014061:regulation of norepinephrine secretion;GO:2000300:regulation of synaptic vesicle exocytosis;GO:0006355:regulation of transcription, DNA-templated;GO:0043279:response to alkaloid;GO:0001975:response to amphetamine;GO:0031000:response to caffeine;GO:0042493:response to drug;GO:0007271:synaptic transmission, cholinergic;GO:0001963:synaptic transmission, dopaminergic;GO:0035249:synaptic transmission, glutamatergic;GO:0042311:vasodilation;	GO:0032279:asymmetric synapse;GO:0030673:axolemma;GO:0030424:axon;GO:0030425:dendrite;GO:0012505:endomembrane system;GO:0005887:integral component of plasma membrane;GO:0005882:intermediate filament;GO:0016020:membrane;GO:0043025:neuronal cell body;GO:0005886:plasma membrane;GO:0014069:postsynaptic density;GO:0045211:postsynaptic membrane;GO:0048786:presynaptic active zone;GO:0042734:presynaptic membrane;	GO:0051393:alpha-actinin binding;GO:0019899:enzyme binding;GO:0001609:G-protein coupled adenosine receptor activity;GO:0042802:identical protein binding;GO:0044877:macromolecular complex binding;GO:0031802:type 5 metabotropic glutamate receptor binding;	K04266	;ko04015 Rap1 signaling pathway;ko04020 Calcium signaling pathway;ko04024 cAMP signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04270 Vascular smooth muscle contraction;ko05012 Parkinson disease;ko05034 Alcoholism;
ENSMUSG00000025507	4528	551	6.32	471	5.92	1338	13.60	867	11.40	796.985618214147	2.22122535786335	1.15135577117324	0.180138476861815	6.39150386542043	1.64262128936909e-10	1.29168999236849e-08	Ups	7	141018026	141023938	-	Pidd1	p53 induced death domain protein 1 [Source:MGI Symbol%3BAcc:MGI:1889507]	GO:0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006915:apoptotic process;GO:0097190:apoptotic signaling pathway;GO:0006974:cellular response to DNA damage stimulus;GO:0006977:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0097191:extrinsic apoptotic signaling pathway;GO:0008625:extrinsic apoptotic signaling pathway via death domain receptors;GO:0043066:negative regulation of apoptotic process;GO:0016540:protein autoprocessing;GO:0043122:regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007165:signal transduction;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005794:Golgi apparatus;GO:0005634:nucleus;	GO:0004175:endopeptidase activity;	K10130	;ko04064 NF-kappa B signaling pathway;ko04115 p53 signaling pathway;ko04210 Apoptosis;
ENSMUSG00000025085	11949	8050	34.97	9310	44.34	4160	16.02	3930	19.59	6275.1404266166	0.486168979957919	-1.04047024983122	0.162957198462221	-6.38492966036375	1.71476269992472e-10	1.34153934901253e-08	Down	19	57021165	57303351	-	Ablim1	actin-binding LIM protein 1 [Source:MGI Symbol%3BAcc:MGI:1194500]	GO:0007411:axon guidance;GO:0060271:cilium morphogenesis;GO:0007010:cytoskeleton organization;GO:0030032:lamellipodium assembly;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0009887:organ morphogenesis;GO:0007601:visual perception;	GO:0015629:actin cytoskeleton;GO:0005737:cytoplasm;GO:0030027:lamellipodium;GO:0014069:postsynaptic density;GO:0001725:stress fiber;	GO:0003779:actin binding;GO:0051015:actin filament binding;GO:0046872:metal ion binding;	K07520	;ko04360 Axon guidance;
ENSMUSG00000031709	5887	463	4.08	420	4.06	177	1.38	166	1.68	301.03358864281	0.405820265760588	-1.3010871830154	0.203946308405354	-6.37955740993077	1.7760049910504e-10	1.38239901181558e-08	Down	8	83891981	83999563	+	Tbc1d9	TBC1 domain family%2C member 9 [Source:MGI Symbol%3BAcc:MGI:1918560]	GO:0090630:activation of GTPase activity;GO:0006886:intracellular protein transport;	-	GO:0005509:calcium ion binding;GO:0005096:GTPase activator activity;	-	-
ENSMUSG00000020717	6228	2023	16.86	2106	19.24	1163	8.59	760	7.27	1482.14495332163	0.478518181408913	-1.06335435360311	0.166908433269321	-6.37088451898229	1.8794111812092e-10	1.45549954811424e-08	Down	11	106545043	106641454	-	Pecam1	platelet/endothelial cell adhesion molecule 1 [Source:MGI Symbol%3BAcc:MGI:97537]	GO:0001525:angiogenesis;GO:0070830:bicellular tight junction assembly;GO:0007155:cell adhesion;GO:0007166:cell surface receptor signaling pathway;GO:0098609:cell-cell adhesion;GO:0098742:cell-cell adhesion via plasma-membrane adhesion molecules;GO:0050904:diapedesis;GO:0043542:endothelial cell migration;GO:0001886:endothelial cell morphogenesis;GO:0061028:establishment of endothelial barrier;GO:0007156:homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007159:leukocyte cell-cell adhesion;GO:0035696:monocyte extravasation;GO:0030837:negative regulation of actin filament polymerization;GO:0034260:negative regulation of GTPase activity;GO:0050732:negative regulation of peptidyl-tyrosine phosphorylation;GO:0072672:neutrophil extravasation;GO:0006909:phagocytosis;GO:0030335:positive regulation of cell migration;GO:0002693:positive regulation of cellular extravasation;GO:0002687:positive regulation of leukocyte migration;GO:0050731:positive regulation of peptidyl-tyrosine phosphorylation;GO:0001934:positive regulation of protein phosphorylation;GO:0042531:positive regulation of tyrosine phosphorylation of STAT protein;GO:0030334:regulation of cell migration;GO:0007266:Rho protein signal transduction;GO:0042060:wound healing;	GO:0071944:cell periphery;GO:0009986:cell surface;GO:0044291:cell-cell contact zone;GO:0005911:cell-cell junction;GO:0005737:cytoplasm;GO:0009897:external side of plasma membrane;GO:0005615:extracellular space;GO:0005887:integral component of plasma membrane;GO:0016020:membrane;GO:0045121:membrane raft;GO:0005886:plasma membrane;GO:0032991:macromolecular complex;GO:0001726:ruffle;GO:0030485:smooth muscle contractile fiber;	GO:0042803:protein homodimerization activity;GO:0019903:protein phosphatase binding;GO:0004888:transmembrane signaling receptor activity;	K06471	;ko04514 Cell adhesion molecules;ko04670 Leukocyte transendothelial migration;ko05144 Malaria;ko05418 Fluid shear stress and atherosclerosis;
ENSMUSG00000026875	8819	2622	15.43	2300	14.84	6018	31.40	3866	26.11	3654.49582685897	2.06503253831817	1.04616451409045	0.164582276822867	6.3564834214585	2.06424708707735e-10	1.5826582416622e-08	Ups	2	34831762	34851784	-	Traf1	TNF receptor-associated factor 1 [Source:MGI Symbol%3BAcc:MGI:101836]	GO:0006915:apoptotic process;GO:0046330:positive regulation of JNK cascade;GO:0051092:positive regulation of NF-kappaB transcription factor activity;GO:0070534:protein K63-linked ubiquitination;GO:2001236:regulation of extrinsic apoptotic signaling pathway;GO:0043122:regulation of I-kappaB kinase/NF-kappaB signaling;GO:0033209:tumor necrosis factor-mediated signaling pathway;	GO:0005737:cytoplasm;GO:0009898:cytoplasmic side of plasma membrane;	GO:0042802:identical protein binding;GO:0031996:thioesterase binding;GO:0005164:tumor necrosis factor receptor binding;GO:0031625:ubiquitin protein ligase binding;GO:0004842:ubiquitin-protein transferase activity;GO:0008270:zinc ion binding;	K03172	;ko04064 NF-kappa B signaling pathway;ko04210 Apoptosis;ko04668 TNF signaling pathway;ko05200 Pathways in cancer;ko05202 Transcriptional misregulation in cancer;ko05203 Viral carcinogenesis;ko05222 Small cell lung cancer;
ENSMUSG00000054469	4894	697	7.39	697	8.10	332	3.12	294	3.58	496.704177285653	0.467718873255404	-1.0962864497469	0.172803053510079	-6.34413818204291	2.23674000340292e-10	1.70637667722291e-08	Down	17	73414980	73550363	+	Lclat1	lysocardiolipin acyltransferase 1 [Source:MGI Symbol%3BAcc:MGI:2684937]	GO:0035965:cardiolipin acyl-chain remodeling;GO:0016024:CDP-diacylglycerol biosynthetic process;GO:0036149:phosphatidylinositol acyl-chain remodeling;	GO:0005829:cytosol;GO:0012505:endomembrane system;GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0016021:integral component of membrane;	GO:0003841:1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0016746:transferase activity, transferring acyl groups;	K13513	;ko00561 Glycerolipid metabolism;ko00564 Glycerophospholipid metabolism;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;
ENSMUSG00000030930	6754	803	6.17	776	6.54	402	2.74	337	2.97	569.510272925212	0.486648469227638	-1.03904807787454	0.163868261220788	-6.34075244427336	2.28645685158078e-10	1.73566977040295e-08	Down	7	131837509	131918957	-	Chst15	carbohydrate sulfotransferase 15 [Source:MGI Symbol%3BAcc:MGI:1924840]	GO:0019319:hexose biosynthetic process;	GO:0000139:Golgi membrane;GO:0016021:integral component of membrane;	GO:0050656:3'-phosphoadenosine 5'-phosphosulfate binding;GO:0050659:N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity;	K08106	;ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate;
ENSMUSG00000022718	7696	1879	12.68	1490	11.02	3319	19.84	3338	25.83	2509.4634620609	2.07823580544523	1.05535935782524	0.166540136656954	6.33696704596266	2.3433208629298e-10	1.7700730104515e-08	Ups	16	18071812	18107110	-	Dgcr8	DGCR8%2C microprocessor complex subunit [Source:MGI Symbol%3BAcc:MGI:2151114]	GO:0031053:primary miRNA processing;GO:0072091:regulation of stem cell proliferation;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0070877:microprocessor complex;GO:0016604:nuclear body;GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0014069:postsynaptic density;	GO:0003725:double-stranded RNA binding;GO:0020037:heme binding;GO:0042802:identical protein binding;GO:0046872:metal ion binding;GO:0070878:primary miRNA binding;GO:0042803:protein homodimerization activity;	K18419	-
ENSMUSG00000026417	4025	567	7.31	582	8.23	185	2.11	224	3.31	384.021216973952	0.375204510680775	-1.41425092295713	0.223367601432517	-6.33149531931739	2.42796537435589e-10	1.82502063972418e-08	Down	1	130754421	130779986	+	Pigr	polymeric immunoglobulin receptor [Source:MGI Symbol%3BAcc:MGI:103080]	GO:0001580:detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007173:epidermal growth factor receptor signaling pathway;GO:0038093:Fc receptor signaling pathway;GO:0002415:immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor;GO:0043113:receptor clustering;	GO:0005615:extracellular space;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;GO:0043235:receptor complex;GO:0055038:recycling endosome membrane;GO:0071751:secretory IgA immunoglobulin complex;GO:0030133:transport vesicle;	GO:0005154:epidermal growth factor receptor binding;GO:0001792:polymeric immunoglobulin receptor activity;GO:0004888:transmembrane signaling receptor activity;	K13073	;ko04672 Intestinal immune network for IgA production;
ENSMUSG00000041774	5594	186	1.73	170	1.73	521	4.29	352	3.75	304.276572863053	2.5284385894949	1.33824673883416	0.211563132392789	6.32551959171018	2.52381880273164e-10	1.88781646444327e-08	Ups	16	16962485	16978565	+	Ydjc	YdjC homolog (bacterial) [Source:MGI Symbol%3BAcc:MGI:1916351]	GO:0005975:carbohydrate metabolic process;	-	GO:0019213:deacetylase activity;GO:0000287:magnesium ion binding;	K04552	;ko04120 Ubiquitin mediated proteolysis;ko05012 Parkinson disease;ko05022 Pathways of neurodegeneration - multiple diseases;
ENSMUSG00000039193	4807	633	6.84	641	7.59	311	2.98	257	3.18	452.479820364725	0.463057794583247	-1.11073582633691	0.176157243871182	-6.30536560363732	2.87514395742593e-10	2.14016783704705e-08	Down	17	74732433	74766137	-	Nlrc4	NLR family%2C CARD domain containing 4 [Source:MGI Symbol%3BAcc:MGI:3036243]	GO:0097202:activation of cysteine-type endopeptidase activity;GO:0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0002218:activation of innate immune response;GO:0006915:apoptotic process;GO:0042742:defense response to bacterium;GO:0016045:detection of bacterium;GO:0006954:inflammatory response;GO:0045087:innate immune response;GO:0043065:positive regulation of apoptotic process;GO:0032731:positive regulation of interleukin-1 beta production;GO:0051092:positive regulation of NF-kappaB transcription factor activity;GO:0010954:positive regulation of protein processing;GO:0051260:protein homooligomerization;GO:0070269:pyroptosis;GO:0042981:regulation of apoptotic process;GO:0043281:regulation of cysteine-type endopeptidase activity involved in apoptotic process;	GO:0005829:cytosol;GO:0072557:IPAF inflammasome complex;	GO:0005524:ATP binding;GO:0089720:caspase binding;GO:0061133:endopeptidase activator activity;GO:0042802:identical protein binding;GO:0042803:protein homodimerization activity;	K12805	;ko04621 NOD-like receptor signaling pathway;ko05131 Shigellosis;ko05132 Salmonella infection;ko05134 Legionellosis;ko05135 Yersinia infection;
ENSMUSG00000046687	1240	175	7.33	124	5.69	36	1.34	20	0.96	86.0780975809932	0.193329083033459	-2.37086941237152	0.376414779874496	-6.29855558052746	3.00432001328234e-10	2.21481937902267e-08	Down	10	61906902	61908141	+	Gm5424	predicted gene 5424 [Source:MGI Symbol%3BAcc:MGI:3643173]	GO:0006526:arginine biosynthetic process;GO:0000053:argininosuccinate metabolic process;GO:0007623:circadian rhythm;GO:0000050:urea cycle;	GO:0005737:cytoplasm;GO:0005829:cytosol;	GO:0004055:argininosuccinate synthase activity;GO:0005524:ATP binding;	K01940	;ko00220 Arginine biosynthesis;ko00250 Alanine, aspartate and glutamate metabolism;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko01230 Biosynthesis of amino acids;ko05418 Fluid shear stress and atherosclerosis;
ENSMUSG00000004267	4705	42	0.46	55	0.67	208	2.03	156	1.97	114.974897577198	3.87428743424044	1.95393099177552	0.31130820547676	6.2765161900668	3.46243347179465e-10	2.54033276825355e-08	Ups	6	124737016	124746636	-	Eno2	enolase 2%2C gamma neuronal [Source:MGI Symbol%3BAcc:MGI:95394]	GO:0006096:glycolytic process;GO:0032889:regulation of vacuole fusion, non-autophagic;GO:0061621:canonical glycolysis;GO:0006094:gluconeogenesis;GO:0048609:multicellular organismal reproductive process;GO:1901215:negative regulation of neuron death;GO:1901214:regulation of neuron death;GO:0042493:response to drug;GO:0032355:response to estradiol;GO:0014070:response to organic cyclic compound;	GO:0005829:cytosol;GO:0000015:phosphopyruvate hydratase complex;GO:0009986:cell surface;GO:0005737:cytoplasm;GO:0030426:growth cone;GO:0016020:membrane;GO:0045121:membrane raft;GO:0043209:myelin sheath;GO:0043005:neuron projection;GO:0043025:neuronal cell body;GO:0043204:perikaryon;GO:0001917:photoreceptor inner segment;GO:0005886:plasma membrane;GO:0097060:synaptic membrane;	GO:0000287:magnesium ion binding;GO:0004634:phosphopyruvate hydratase activity;GO:0019899:enzyme binding;GO:0042802:identical protein binding;GO:0044877:macromolecular complex binding;	K01689	;ko00010 Glycolysis / Gluconeogenesis;ko00680 Methane metabolism;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko01120 Microbial metabolism in diverse environments;ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko03018 RNA degradation;ko04066 HIF-1 signaling pathway;
ENSMUSG00000062797	5210	490	4.88	580	6.34	244	2.16	172	1.97	364.406175900759	0.400573558349368	-1.31986090213727	0.210644297457803	-6.26582783425063	3.70849896052433e-10	2.69507692230711e-08	Down	7	89566737	89590412	-	Hikeshi	heat shock protein nuclear import factor [Source:MGI Symbol%3BAcc:MGI:96738]	GO:0034605:cellular response to heat;GO:0007030:Golgi organization;GO:0030324:lung development;GO:0006606:protein import into nucleus;GO:0015031:protein transport;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005634:nucleus;	GO:0030544:Hsp70 protein binding;GO:0061608:nuclear import signal receptor activity;	-	-
ENSMUSG00000048078	21021	110	0.27	85	0.23	5	0.01	13	0.04	51.935900464811	0.0982988555437258	-3.346681569862	0.535481783137519	-6.24985139597647	4.10843398370881e-10	2.95768669982117e-08	Down	7	95820453	96560300	+	Tenm4	teneurin transmembrane protein 4 [Source:MGI Symbol%3BAcc:MGI:2447063]	GO:0060912:cardiac cell fate specification;GO:0060038:cardiac muscle cell proliferation;GO:0032289:central nervous system myelin formation;GO:0001702:gastrulation with mouth forming second;GO:0007157:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0048666:neuron development;GO:2000543:positive regulation of gastrulation;GO:0031643:positive regulation of myelination;GO:0048714:positive regulation of oligodendrocyte differentiation;GO:0031641:regulation of myelination;GO:0007165:signal transduction;	GO:0005737:cytoplasm;GO:0005887:integral component of plasma membrane;GO:0043005:neuron projection;GO:0005634:nucleus;GO:0005886:plasma membrane;	GO:0050839:cell adhesion molecule binding;GO:0042802:identical protein binding;GO:0046982:protein heterodimerization activity;GO:0042803:protein homodimerization activity;	-	-
ENSMUSG00000051735	3624	1147	16.43	1155	18.14	642	8.15	422	6.94	824.114325261045	0.475510860758273	-1.07244980199677	0.172624547309411	-6.21261471043579	5.21101128071768e-10	3.73390873731425e-08	Down	7	28488394	28498388	+	Rinl	Ras and Rab interactor-like [Source:MGI Symbol%3BAcc:MGI:2444024]	GO:0006897:endocytosis;GO:0015031:protein transport;	GO:0015629:actin cytoskeleton;GO:0031410:cytoplasmic vesicle;GO:0001726:ruffle;	GO:0005085:guanyl-nucleotide exchange factor activity;	-	-
ENSMUSG00000072235	1803	859	24.73	680	21.46	389	9.93	252	8.32	532.046905423735	0.429756684451712	-1.21840801527632	0.196446240876248	-6.20224652730237	5.56627914108973e-10	3.96092336606264e-08	Down	15	98847718	98851584	-	Tuba1a	tubulin%2C alpha 1A [Source:MGI Symbol%3BAcc:MGI:98869]	GO:0000226:microtubule cytoskeleton organization;GO:0000278:mitotic cell cycle;GO:0050807:regulation of synapse organization;	GO:0005737:cytoplasm;GO:0005881:cytoplasmic microtubule;GO:0036464:cytoplasmic ribonucleoprotein granule;GO:0005874:microtubule;GO:0031594:neuromuscular junction;GO:0055037:recycling endosome;	GO:0005525:GTP binding;GO:0042802:identical protein binding;GO:0005200:structural constituent of cytoskeleton;	K07374	;ko04145 Phagosome;ko04210 Apoptosis;ko04530 Tight junction;ko04540 Gap junction;ko05010 Alzheimer disease;ko05012 Parkinson disease;ko05014 Amyotrophic lateral sclerosis;ko05016 Huntington disease;ko05020 Prion disease;ko05022 Pathways of neurodegeneration - multiple diseases;ko05130 Pathogenic Escherichia coli infection;ko05132 Salmonella infection;
ENSMUSG00000025815	6333	120	0.98	128	1.15	24	0.17	22	0.21	71.9047230276001	0.19301691864115	-2.37320078433748	0.383394434784291	-6.18997191670952	6.01749349157629e-10	4.25217719814888e-08	Down	2	5900926	5947603	-	Dhtkd1	dehydrogenase E1 and transketolase domain containing 1 [Source:MGI Symbol%3BAcc:MGI:2445096]	GO:0006091:generation of precursor metabolites and energy;GO:0006096:glycolytic process;GO:0002244:hematopoietic progenitor cell differentiation;GO:0006099:tricarboxylic acid cycle;	GO:0005739:mitochondrion;	GO:0004591:oxoglutarate dehydrogenase (succinyl-transferring) activity;GO:0030976:thiamine pyrophosphate binding;	K15791	;ko00310 Lysine degradation;ko00380 Tryptophan metabolism;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;
ENSMUSG00000015568	10478	408	2.02	274	1.49	108	0.47	104	0.59	218.461252058496	0.326305890061996	-1.61570306551294	0.261239984140006	-6.18474645384695	6.2202363627058e-10	4.3715506353381e-08	Down	8	69333143	69360100	+	Lpl	lipoprotein lipase [Source:MGI Symbol%3BAcc:MGI:96820]	GO:0071398:cellular response to fatty acid;GO:0031670:cellular response to nutrient;GO:0042632:cholesterol homeostasis;GO:0034371:chylomicron remodeling;GO:0006633:fatty acid biosynthetic process;GO:0006631:fatty acid metabolic process;GO:0016042:lipid catabolic process;GO:0055096:low-density lipoprotein particle mediated signaling;GO:1900077:negative regulation of cellular response to insulin stimulus;GO:2000343:positive regulation of chemokine (C-X-C motif) ligand 2 production;GO:0032722:positive regulation of chemokine production;GO:0010886:positive regulation of cholesterol storage;GO:0045600:positive regulation of fat cell differentiation;GO:0050729:positive regulation of inflammatory response;GO:0032731:positive regulation of interleukin-1 beta production;GO:0032755:positive regulation of interleukin-6 production;GO:0010744:positive regulation of macrophage derived foam cell differentiation;GO:0010890:positive regulation of sequestering of triglyceride;GO:0032760:positive regulation of tumor necrosis factor production;GO:0009617:response to bacterium;GO:0019432:triglyceride biosynthetic process;GO:0019433:triglyceride catabolic process;GO:0070328:triglyceride homeostasis;GO:0034372:very-low-density lipoprotein particle remodeling;GO:0006310:DNA recombination;	GO:0009986:cell surface;GO:0042627:chylomicron;GO:0005615:extracellular space;GO:0005886:plasma membrane;GO:0034361:very-low-density lipoprotein particle;	GO:0052740:1-acyl-2-lysophosphatidylserine acylhydrolase activity;GO:0034185:apolipoprotein binding;GO:0005509:calcium ion binding;GO:0043395:heparan sulfate proteoglycan binding;GO:0008201:heparin binding;GO:0016298:lipase activity;GO:0004465:lipoprotein lipase activity;GO:0071813:lipoprotein particle binding;GO:0052739:phosphatidylserine 1-acylhydrolase activity;GO:0008970:phosphatidylcholine 1-acylhydrolase activity;GO:0004620:phospholipase activity;GO:0042803:protein homodimerization activity;GO:0005102:receptor binding;GO:0017129:triglyceride binding;GO:0004806:triglyceride lipase activity;GO:0004519:endonuclease activity;GO:0046872:metal ion binding;GO:0003964:RNA-directed DNA polymerase activity;	K01059	;ko00561 Glycerolipid metabolism;ko03320 PPAR signaling pathway;ko04979 Cholesterol metabolism;ko05010 Alzheimer disease;
ENSMUSG00000031838	980	1664	88.15	1450	84.20	4110	192.98	2463	149.68	2386.33031102025	2.16397525490999	1.11368400201928	0.180086574408244	6.18415895620645	6.24344325772169e-10	4.3715506353381e-08	Ups	8	71215419	71219307	-	Ifi30	interferon gamma inducible protein 30 [Source:MGI Symbol%3BAcc:MGI:2137648]	GO:0042590:antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0019886:antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0048147:negative regulation of fibroblast proliferation;GO:0050821:protein stabilization;	GO:0030054:cell junction;GO:0005829:cytosol;GO:0005576:extracellular region;GO:0043231:intracellular membrane-bounded organelle;GO:0005764:lysosome;	GO:0015036:disulfide oxidoreductase activity;GO:0016491:oxidoreductase activity;GO:0016667:oxidoreductase activity, acting on a sulfur group of donors;GO:0016671:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;	K08059	;ko04612 Antigen processing and presentation;
ENSMUSG00000002668	5109	1895	19.26	2232	24.86	1102	9.93	881	10.27	1503.15580965563	0.497272412607413	-1.00789169853145	0.163001989819668	-6.18330917092787	6.27716037496428e-10	4.37518078135011e-08	Down	17	57372905	57385514	-	Dennd1c	DENN/MADD domain containing 1C [Source:MGI Symbol%3BAcc:MGI:1918035]	GO:0032456:endocytic recycling;GO:0006897:endocytosis;	GO:0005813:centrosome;GO:0030136:clathrin-coated vesicle;GO:0005829:cytosol;GO:0043231:intracellular membrane-bounded organelle;GO:0005654:nucleoplasm;	GO:0005085:guanyl-nucleotide exchange factor activity;GO:1901981:phosphatidylinositol phosphate binding;	-	-
ENSMUSG00000027405	4099	6908	87.49	4980	69.14	14729	165.35	10192	148.08	9101.79349492173	2.16893538443042	1.11698707377996	0.180834952988236	6.17683172042865	6.54007154882573e-10	4.53780349003139e-08	Ups	2	130116350	130121233	+	Nop56	NOP56 ribonucleoprotein [Source:MGI Symbol%3BAcc:MGI:1914384]	GO:0042254:ribosome biogenesis;	GO:0031428:box C/D snoRNP complex;GO:0005737:cytoplasm;GO:0001650:fibrillar center;GO:0005654:nucleoplasm;GO:0070761:pre-snoRNP complex;GO:0032040:small-subunit processome;GO:0005732:small nucleolar ribonucleoprotein complex;GO:0005730:nucleolus;	GO:1990226:histone methyltransferase binding;GO:0030515:snoRNA binding;	K14564	;ko03008 Ribosome biogenesis in eukaryotes;ko05017 Spinocerebellar ataxia;
ENSMUSG00000021792	2948	1245	21.92	1073	20.71	548	8.55	536	10.83	836.979324235901	0.490186238479689	-1.02859811242841	0.166633940691284	-6.17280074012084	6.70907456710233e-10	4.61436935431461e-08	Down	14	40715697	40735745	-	Prxl2a	peroxiredoxin like 2A [Source:MGI Symbol%3BAcc:MGI:1917814]	GO:0045670:regulation of osteoclast differentiation;	GO:0005737:cytoplasm;GO:0005576:extracellular region;GO:0005739:mitochondrion;	GO:0016209:antioxidant activity;	-	-
ENSMUSG00000041845	1714	1	0.03	3	0.10	83	2.23	60	2.08	36.8056124198154	36.8768119671679	5.20464203379017	0.844807576153391	6.16074261252264	7.24045933336922e-10	4.95648229544123e-08	Ups	19	4475487	4489460	-	Rhod	ras homolog family member D [Source:MGI Symbol%3BAcc:MGI:108446]	GO:0051017:actin filament bundle assembly;GO:0007015:actin filament organization;GO:0016477:cell migration;GO:0030865:cortical cytoskeleton organization;GO:0007163:establishment or maintenance of cell polarity;GO:0048041:focal adhesion assembly;GO:0030032:lamellipodium assembly;GO:0045785:positive regulation of cell adhesion;GO:0030335:positive regulation of cell migration;GO:0006605:protein targeting;GO:0032956:regulation of actin cytoskeleton organization;GO:2000249:regulation of actin cytoskeleton reorganization;GO:0008360:regulation of cell shape;GO:0051893:regulation of focal adhesion assembly;GO:0007264:small GTPase mediated signal transduction;	GO:0005938:cell cortex;GO:0042995:cell projection;GO:0031410:cytoplasmic vesicle;GO:0005856:cytoskeleton;GO:0005769:early endosome;GO:0043231:intracellular membrane-bounded organelle;GO:0005886:plasma membrane;	GO:0005525:GTP binding;GO:0003924:GTPase activity;GO:0019901:protein kinase binding;	K07530	;ko04360 Axon guidance;
ENSMUSG00000020077	2196	2373	56.10	2259	58.54	5961	124.91	3599	97.61	3497.91280683509	2.11391527964026	1.07991755832321	0.175323229903902	6.15958055823594	7.2937870204029e-10	4.97079689648258e-08	Ups	10	62329612	62363230	-	Srgn	serglycin [Source:MGI Symbol%3BAcc:MGI:97756]	GO:0006915:apoptotic process;GO:0031214:biomineral tissue development;GO:0033382:maintenance of granzyme B location in T cell secretory granule;GO:0033373:maintenance of protease location in mast cell secretory granule;GO:0033364:mast cell secretory granule organization;GO:0050804:regulation of synaptic transmission;GO:0030502:negative regulation of bone mineralization;GO:0001818:negative regulation of cytokine production;GO:0016485:protein processing;GO:0033363:secretory granule organization;GO:0033371:T cell secretory granule organization;	GO:0005615:extracellular space;GO:0005794:Golgi apparatus;GO:0042629:mast cell granule;GO:0030141:secretory granule;GO:0042588:zymogen granule;	GO:0005518:collagen binding;	K06849	-
ENSMUSG00000039264	2577	3971	80.00	5602	123.71	2320	41.43	1645	38.02	3327.02308808712	0.425125109427953	-1.23404062260195	0.200741034931802	-6.14742582661883	7.8750505642283e-10	5.34318696247242e-08	Down	6	48741398	48747785	-	Gimap3	GTPase%2C IMAP family member 3 [Source:MGI Symbol%3BAcc:MGI:1932723]	GO:0000002:mitochondrial genome maintenance;	GO:0005789:endoplasmic reticulum membrane;GO:0016021:integral component of membrane;GO:0005741:mitochondrial outer membrane;GO:0005739:mitochondrion;	GO:0005525:GTP binding;	-	-
ENSMUSG00000025577	4257	161	1.96	194	2.59	468	5.06	382	5.34	300.56328512901	2.48125343954286	1.31106910213791	0.213357460764843	6.14494143976964	7.9993021337497e-10	5.4035814501726e-08	Ups	11	118913788	118922096	+	Cbx2	chromobox 2 [Source:MGI Symbol%3BAcc:MGI:88289]	GO:0006325:chromatin organization;GO:0045137:development of primary sexual characteristics;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;	GO:0000791:euchromatin;GO:0000792:heterochromatin;GO:0016607:nuclear speck;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0031519:PcG protein complex;GO:0035102:PRC1 complex;	GO:0003682:chromatin binding;GO:0003677:DNA binding;GO:0035064:methylated histone binding;	K11451	-
ENSMUSG00000030122	1619	1189	38.13	1191	41.86	652	18.53	390	14.35	836.371702361321	0.44859474736736	-1.15651536699868	0.188232806431342	-6.14406908617448	8.04338308925215e-10	5.40952790748213e-08	Down	6	124890644	124897066	-	Ptms	parathymosin [Source:MGI Symbol%3BAcc:MGI:1916452]	-	-	-	-	-
ENSMUSG00000038670	3611	141	2.03	112	1.77	363	4.63	282	4.65	223.339480866084	2.64799047821108	1.40489793443276	0.228966729456133	6.13581692750659	8.47226793764643e-10	5.6730898059332e-08	Ups	7	44151123	44174080	-	Mybpc2	myosin binding protein C%2C fast-type [Source:MGI Symbol%3BAcc:MGI:1336170]	GO:0007155:cell adhesion;GO:0006936:muscle contraction;	GO:0005856:cytoskeleton;GO:0032982:myosin filament;	GO:0003779:actin binding;GO:0005200:structural constituent of cytoskeleton;	K12558	-
ENSMUSG00000003872	1463	7	0.25	8	0.31	108	3.40	56	2.28	44.0974973233652	11.1404044896947	3.47772971039139	0.567043086300692	6.1330960458042	8.61850787314061e-10	5.74592172724948e-08	Ups	7	45017315	45020007	-	Lin7b	lin-7 homolog B%2C crumbs cell polarity complex component [Source:MGI Symbol%3BAcc:MGI:1330858]	GO:0006887:exocytosis;GO:0045199:maintenance of epithelial cell apical/basal polarity;GO:0007269:neurotransmitter secretion;GO:1903361:protein localization to basolateral plasma membrane;GO:0015031:protein transport;GO:0007043:cell-cell junction assembly;	GO:0016323:basolateral plasma membrane;GO:0005923:bicellular tight junction;GO:0005911:cell-cell junction;GO:0097025:MPP7-DLG1-LIN7 complex;GO:0005886:plasma membrane;GO:0098793:presynapse;GO:0045202:synapse;GO:0030658:transport vesicle membrane;	GO:0097016:L27 domain binding;GO:0030165:PDZ domain binding;GO:0019904:protein domain specific binding;	-	-
ENSMUSG00000036880	1516	406	13.90	359	13.48	173	5.25	112	4.40	256.374267024609	0.384291995674844	-1.37972516772024	0.22501088882558	-6.13181510868905	8.68820424814147e-10	5.76731272471867e-08	Down	18	74912268	74939279	+	Acaa2	acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) [Source:MGI Symbol%3BAcc:MGI:1098623]	GO:0006084:acetyl-CoA metabolic process;GO:0071456:cellular response to hypoxia;GO:0006635:fatty acid beta-oxidation;GO:1902109:negative regulation of mitochondrial membrane permeability involved in apoptotic process;GO:1901029:negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;	GO:0005743:mitochondrial inner membrane;GO:0005759:mitochondrial matrix;GO:0005739:mitochondrion;	GO:0003985:acetyl-CoA C-acetyltransferase activity;GO:0003988:acetyl-CoA C-acyltransferase activity;GO:0003986:acetyl-CoA hydrolase activity;GO:0047617:acyl-CoA hydrolase activity;GO:0016290:palmitoyl-CoA hydrolase activity;	K07508	;ko00062 Fatty acid elongation;ko00071 Fatty acid degradation;ko00280 Valine, leucine and isoleucine degradation;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko01212 Fatty acid metabolism;
ENSMUSG00000086841	2076	827	20.68	772	21.16	2246	49.78	1292	37.06	1264.49625960082	2.26256432750513	1.17795881038517	0.192319971329587	6.12499472749222	9.06866094959454e-10	5.97908863993227e-08	Ups	11	62493650	62495725	+	2410006H16Rik	RIKEN cDNA 2410006H16 gene [Source:MGI Symbol%3BAcc:MGI:1916471]	-	-	-	-	-
ENSMUSG00000012429	4503	381	4.39	398	5.03	883	9.02	666	8.81	578.005063439299	2.05647812680619	1.04017572706997	0.1698328090007	6.12470424996437	9.08522011937015e-10	5.97908863993227e-08	Ups	13	17869777	17874333	+	Mplkip	M-phase specific PLK1 intereacting protein [Source:MGI Symbol%3BAcc:MGI:1913558]	GO:0007049:cell cycle;GO:0051301:cell division;	GO:0005813:centrosome;GO:0005737:cytoplasm;GO:0005794:Golgi apparatus;GO:0043231:intracellular membrane-bounded organelle;GO:0030496:midbody;GO:0005654:nucleoplasm;GO:0005634:nucleus;	-	-	-
ENSMUSG00000039747	6077	992	8.47	787	7.37	467	3.54	315	3.09	625.630028392257	0.454216592161301	-1.13854768740792	0.186071657179122	-6.11886681006925	9.42431320388232e-10	6.17574438753553e-08	Down	5	136176313	136199567	-	Orai2	ORAI calcium release-activated calcium modulator 2 [Source:MGI Symbol%3BAcc:MGI:2443195]	GO:0002115:store-operated calcium entry;	GO:0030426:growth cone;GO:0016021:integral component of membrane;GO:0016020:membrane;	GO:0015279:store-operated calcium channel activity;	K16057	;ko04020 Calcium signaling pathway;
ENSMUSG00000046618	5579	213	1.98	145	1.48	462	3.81	429	4.58	312.337916459357	2.60986943000212	1.38397763154595	0.22642408090161	6.11232527050576	9.81897909396236e-10	6.37984006045842e-08	Ups	2	38821990	38853765	+	Olfml2a	olfactomedin-like 2A [Source:MGI Symbol%3BAcc:MGI:2444741]	-	GO:0005576:extracellular region;	-	-	-
ENSMUSG00000040760	8719	2741	16.32	2562	16.72	1031	5.44	1228	8.39	1865.5865646275	0.450394225967084	-1.15073976263363	0.18869927995163	-6.09827320447963	1.07220382399371e-09	6.90805606601662e-08	Down	14	26640945	26693189	-	Appl1	adaptor protein%2C phosphotyrosine interaction%2C PH domain and leucine zipper containing 1 [Source:MGI Symbol%3BAcc:MGI:1920243]	GO:0033211:adiponectin-activated signaling pathway;GO:0007049:cell cycle;GO:0035729:cellular response to hepatocyte growth factor stimulus;GO:0008286:insulin receptor signaling pathway;GO:1900017:positive regulation of cytokine production involved in inflammatory response;GO:0046326:positive regulation of glucose import;GO:0048023:positive regulation of melanin biosynthetic process;GO:0006606:protein import into nucleus;GO:0010762:regulation of fibroblast migration;GO:2000045:regulation of G1/S transition of mitotic cell cycle;GO:0046324:regulation of glucose import;GO:0045088:regulation of innate immune response;GO:1903076:regulation of protein localization to plasma membrane;GO:0034143:regulation of toll-like receptor 4 signaling pathway;GO:0023052:signaling;GO:0007179:transforming growth factor beta receptor signaling pathway;	GO:0005737:cytoplasm;GO:0031410:cytoplasmic vesicle;GO:0005829:cytosol;GO:0005769:early endosome;GO:0031901:early endosome membrane;GO:0032009:early phagosome;GO:0005768:endosome;GO:0010008:endosome membrane;GO:0044354:macropinosome;GO:0016020:membrane;GO:0005634:nucleus;GO:0005886:plasma membrane;GO:0001726:ruffle;GO:0012506:vesicle membrane;	GO:0048487:beta-tubulin binding;GO:0042802:identical protein binding;GO:0035091:phosphatidylinositol binding;GO:0001786:phosphatidylserine binding;GO:0042803:protein homodimerization activity;GO:0043422:protein kinase B binding;GO:0044877:macromolecular complex binding;	K08733	;ko04211 Longevity regulating pathway;ko05200 Pathways in cancer;ko05210 Colorectal cancer;
ENSMUSG00000030852	15793	442	1.45	362	1.30	167	0.49	146	0.55	273.724761945835	0.406209689933335	-1.29970344005874	0.213407067153939	-6.09025491700896	1.12731039375136e-09	7.20257399074306e-08	Down	7	130179168	130366515	+	Tacc2	transforming%2C acidic coiled-coil containing protein 2 [Source:MGI Symbol%3BAcc:MGI:1928899]	GO:0030953:astral microtubule organization;GO:0008283:cell proliferation;GO:0021987:cerebral cortex development;GO:0022027:interkinetic nuclear migration;GO:0000226:microtubule cytoskeleton organization;GO:0007052:mitotic spindle organization;GO:0022008:neurogenesis;GO:0032886:regulation of microtubule-based process;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005815:microtubule organizing center;GO:0005654:nucleoplasm;GO:0005886:plasma membrane;	GO:0016922:ligand-dependent nuclear receptor binding;GO:0019904:protein domain specific binding;	K14282	-
ENSMUSG00000037940	13066	1505	5.98	1628	7.09	485	1.71	659	3.00	1056.67018223717	0.387401078314991	-1.36810012525821	0.224783251395438	-6.08630810687695	1.15543991774083e-09	7.35166626499496e-08	Down	8	82069185	82854543	+	Inpp4b	inositol polyphosphate-4-phosphatase%2C type II [Source:MGI Symbol%3BAcc:MGI:2158925]	GO:0006874:cellular calcium ion homeostasis;GO:0046855:inositol phosphate dephosphorylation;GO:0045671:negative regulation of osteoclast differentiation;GO:0046856:phosphatidylinositol dephosphorylation;GO:0046850:regulation of bone remodeling;GO:0046822:regulation of nucleocytoplasmic transport;GO:0051896:regulation of protein kinase B signaling;	GO:0005737:cytoplasm;	GO:0017161:inositol-1,3,4-trisphosphate 4-phosphatase activity;GO:0052828:inositol-3,4-bisphosphate 4-phosphatase activity;GO:0008289:lipid binding;GO:0034593:phosphatidylinositol bisphosphate phosphatase activity;GO:0034594:phosphatidylinositol trisphosphate phosphatase activity;GO:0016316:phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity;GO:0034597:phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity;	K01109	;ko00562 Inositol phosphate metabolism;ko01100 Metabolic pathways;ko04070 Phosphatidylinositol signaling system;
ENSMUSG00000068566	4479	184	2.13	220	2.80	57	0.59	53	0.70	126.196942773157	0.283244418014789	-1.81988057019809	0.299055145164605	-6.08543474213224	1.16175637270585e-09	7.36131083432706e-08	Down	7	3337605	3348958	+	Myadm	myeloid-associated differentiation marker [Source:MGI Symbol%3BAcc:MGI:1355332]	GO:0061028:establishment of endothelial barrier;GO:0031579:membrane raft organization;GO:0030837:negative regulation of actin filament polymerization;GO:0010629:negative regulation of gene expression;GO:0034115:negative regulation of heterotypic cell-cell adhesion;GO:0090038:negative regulation of protein kinase C signaling;GO:0001933:negative regulation of protein phosphorylation;GO:0030335:positive regulation of cell migration;GO:1900026:positive regulation of substrate adhesion-dependent cell spreading;GO:0072659:protein localization to plasma membrane;	GO:0005911:cell-cell junction;GO:0030864:cortical actin cytoskeleton;GO:0016021:integral component of membrane;GO:0045121:membrane raft;GO:0005886:plasma membrane;GO:0001726:ruffle;	-	-	-
ENSMUSG00000106149	3897	10	0.13	8	0.12	74	0.87	86	1.31	45.3647881636162	9.38054531854952	3.22967179326296	0.531304322601591	6.07876061961722	1.21115007447357e-09	7.61138329589249e-08	Ups	3	135356431	135360327	-	Gm43430	predicted gene 43430 [Source:MGI Symbol%3BAcc:MGI:5663567]	-	-	-	-	-
ENSMUSG00000024592	3233	434	6.97	438	7.71	182	2.59	171	3.15	301.230725711346	0.422411555573126	-1.24327879300347	0.204570507736813	-6.07750748999948	1.22064981189611e-09	7.63977314923061e-08	Down	18	57088905	57108440	-	C330018D20Rik	RIKEN cDNA C330018D20 gene [Source:MGI Symbol%3BAcc:MGI:1924672]	-	GO:0005739:mitochondrion;	-	-	-
ENSMUSG00000016756	10660	2594	12.63	2727	14.56	1018	4.39	1218	6.80	1866.31711353426	0.443683094203134	-1.17239851214609	0.192931161360102	-6.07677113370937	1.22626583061962e-09	7.64372367752894e-08	Down	13	24511387	24661360	+	Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase [Source:MGI Symbol%3BAcc:MGI:103227]	GO:0046381:CMP-N-acetylneuraminate metabolic process;GO:0006054:N-acetylneuraminate metabolic process;	GO:0005737:cytoplasm;GO:0005783:endoplasmic reticulum;	GO:0051537:2 iron, 2 sulfur cluster binding;GO:0030338:CMP-N-acetylneuraminate monooxygenase activity;GO:0046872:metal ion binding;	K08080	;ko00520 Amino sugar and nucleotide sugar metabolism;
ENSMUSG00000028633	3316	1806	28.27	1317	22.60	3246	45.04	2753	49.44	2269.01296691322	2.0062728240373	1.00451780491438	0.165353430389459	6.07497408761599	1.24007744119186e-09	7.66747882388547e-08	Ups	4	120397065	120427473	-	Ctps	cytidine 5'-triphosphate synthase [Source:MGI Symbol%3BAcc:MGI:1858304]	GO:0044210:'de novo' CTP biosynthetic process;GO:0042100:B cell proliferation;GO:0006241:CTP biosynthetic process;GO:0006541:glutamine metabolic process;GO:0019856:pyrimidine nucleobase biosynthetic process;GO:0042098:T cell proliferation;	GO:0097268:cytoophidium;GO:0005737:cytoplasm;GO:0005829:cytosol;	GO:0005524:ATP binding;GO:0003883:CTP synthase activity;GO:0042802:identical protein binding;	K01937	;ko00240 Pyrimidine metabolism;ko01100 Metabolic pathways;ko01240 Biosynthesis of cofactors;
ENSMUSG00000041954	1524	248	8.45	239	8.92	654	19.75	436	17.04	390.130847430627	2.30482465766308	1.2046570000507	0.198381668764656	6.07242094268199	1.25996132184639e-09	7.7591353048966e-08	Ups	4	156110621	156113352	+	Tnfrsf18	tumor necrosis factor receptor superfamily%2C member 18 [Source:MGI Symbol%3BAcc:MGI:894675]	GO:0006915:apoptotic process;GO:0043066:negative regulation of apoptotic process;GO:0045785:positive regulation of cell adhesion;GO:0002687:positive regulation of leukocyte migration;GO:0042531:positive regulation of tyrosine phosphorylation of STAT protein;	GO:0009897:external side of plasma membrane;GO:0005576:extracellular region;GO:0005887:integral component of plasma membrane;	GO:0005031:tumor necrosis factor-activated receptor activity;	K05154	;ko04060 Cytokine-cytokine receptor interaction;
ENSMUSG00000052749	7527	709	4.89	631	4.77	355	2.17	239	1.89	472.996946215781	0.457516968585994	-1.12810284320459	0.186228463681104	-6.0576284683116	1.381430061708e-09	8.43938189889661e-08	Down	7	104004589	104019091	-	Trim30b	tripartite motif-containing 30B [Source:MGI Symbol%3BAcc:MGI:4821256]	GO:0045087:innate immune response;GO:0032715:negative regulation of interleukin-6 production;GO:1900226:negative regulation of NLRP3 inflammasome complex assembly;GO:2000378:negative regulation of reactive oxygen species metabolic process;GO:0034122:negative regulation of toll-like receptor signaling pathway;GO:0032720:negative regulation of tumor necrosis factor production;GO:0010508:positive regulation of autophagy;GO:0043123:positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092:positive regulation of NF-kappaB transcription factor activity;GO:0045732:positive regulation of protein catabolic process;GO:0046598:positive regulation of viral entry into host cell;GO:0051865:protein autoubiquitination;GO:0000209:protein polyubiquitination;GO:0016567:protein ubiquitination;GO:0010468:regulation of gene expression;GO:0032880:regulation of protein localization;GO:0046596:regulation of viral entry into host cell;GO:0009617:response to bacterium;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005654:nucleoplasm;	GO:0003677:DNA binding;GO:0042803:protein homodimerization activity;GO:0019901:protein kinase binding;GO:0061630:ubiquitin protein ligase activity;GO:0008270:zinc ion binding;	K10648	;ko05170 Human immunodeficiency virus 1 infection;
ENSMUSG00000029146	3091	1397	23.46	1282	23.60	769	11.45	492	9.48	963.498879288046	0.484191015146994	-1.04635178656072	0.172850594876566	-6.05350411034414	1.41728454394878e-09	8.62406396702801e-08	Down	5	31350571	31356487	+	Snx17	sorting nexin 17 [Source:MGI Symbol%3BAcc:MGI:2387801]	GO:0035904:aorta development;GO:0003279:cardiac septum development;GO:0060976:coronary vasculature development;GO:0032456:endocytic recycling;GO:0006886:intracellular protein transport;GO:0001822:kidney development;GO:0006898:receptor-mediated endocytosis;GO:0007165:signal transduction;	GO:0005737:cytoplasm;GO:0031410:cytoplasmic vesicle;GO:0005829:cytosol;GO:0005769:early endosome;GO:0005768:endosome;GO:0010008:endosome membrane;GO:0005794:Golgi apparatus;GO:0043231:intracellular membrane-bounded organelle;GO:0032991:macromolecular complex;	GO:0050750:low-density lipoprotein particle receptor binding;GO:0035091:phosphatidylinositol binding;GO:0008022:protein C-terminus binding;	K17929	-
ENSMUSG00000021066	9175	77	0.44	65	0.40	220	1.10	207	1.34	142.718071044627	3.14595835552768	1.65349957327383	0.273327847715053	6.0495100923548	1.45286963646408e-09	8.77098543525203e-08	Ups	12	69939388	70013191	+	Atl1	atlastin GTPase 1 [Source:MGI Symbol%3BAcc:MGI:1921241]	GO:0007029:endoplasmic reticulum organization;GO:0007030:Golgi organization;GO:0051260:protein homooligomerization;GO:0007409:axonogenesis;	GO:0005783:endoplasmic reticulum;GO:0016021:integral component of membrane;GO:0016020:membrane;GO:0030424:axon;GO:0005789:endoplasmic reticulum membrane;GO:0071782:endoplasmic reticulum tubular network;GO:0005794:Golgi apparatus;GO:0000137:Golgi cis cisterna;GO:0000139:Golgi membrane;GO:0005737:cytoplasm;	GO:0005525:GTP binding;GO:0003924:GTPase activity;GO:0042802:identical protein binding;	K17339	-
ENSMUSG00000047221	3894	331	4.41	340	4.97	704	8.32	630	9.64	500.552398664998	2.07184924629383	1.05091903220557	0.174185245379043	6.03334128512825	1.60603725465889e-09	9.65763735801546e-08	Ups	5	21629956	21687122	+	Fam185a	family with sequence similarity 185%2C member A [Source:MGI Symbol%3BAcc:MGI:2140983]	-	-	-	-	-
ENSMUSG00000058748	2364	318	6.98	364	8.76	744	14.48	656	16.53	519.925458532071	2.13527942408115	1.09442487422914	0.181614456461279	6.02608897746244	1.6797473230761e-09	1.00614240047066e-07	Ups	8	4663167	4680231	+	Zfp958	zinc finger protein 958 [Source:MGI Symbol%3BAcc:MGI:2385298]	GO:0030154:cell differentiation;GO:0043433:negative regulation of sequence-specific DNA binding transcription factor activity;GO:0045668:negative regulation of osteoblast differentiation;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005634:nucleus;	GO:0003682:chromatin binding;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0042826:histone deacetylase binding;GO:0046872:metal ion binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000026879	3157	1398	22.99	1365	24.61	748	10.90	406	7.66	955.620090549593	0.426182585339943	-1.23045645192396	0.2044272249844	-6.01904395081356	1.75450231153152e-09	1.04683028968966e-07	Down	2	35146392	35197904	+	Gsn	gelsolin [Source:MGI Symbol%3BAcc:MGI:95851]	GO:0030036:actin cytoskeleton organization;GO:0051693:actin filament capping;GO:0030042:actin filament depolymerization;GO:0030041:actin filament polymerization;GO:0090527:actin filament reorganization;GO:0051014:actin filament severing;GO:0045010:actin nucleation;GO:0008154:actin polymerization or depolymerization;GO:0007568:aging;GO:1990000:amyloid fibril formation;GO:0006915:apoptotic process;GO:0051016:barbed-end actin filament capping;GO:0086003:cardiac muscle cell contraction;GO:0030031:cell projection assembly;GO:0071276:cellular response to cadmium ion;GO:0071346:cellular response to interferon-gamma;GO:0007417:central nervous system development;GO:0060271:cilium morphogenesis;GO:0097284:hepatocyte apoptotic process;GO:0046597:negative regulation of viral entry into host cell;GO:0014003:oligodendrocyte development;GO:0006911:phagocytosis, engulfment;GO:0048015:phosphatidylinositol-mediated signaling;GO:0051127:positive regulation of actin nucleation;GO:2001269:positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0010628:positive regulation of gene expression;GO:1902174:positive regulation of keratinocyte apoptotic process;GO:1903923:positive regulation of protein processing in phagocytic vesicle;GO:0031648:protein destabilization;GO:0030155:regulation of cell adhesion;GO:1903903:regulation of establishment of T cell polarity;GO:1903906:regulation of plasma membrane raft polarization;GO:0071801:regulation of podosome assembly;GO:1903909:regulation of receptor clustering;GO:0055119:relaxation of cardiac muscle;GO:0097017:renal protein absorption;GO:0045471:response to ethanol;GO:0051593:response to folic acid;GO:0035994:response to muscle stretch;GO:0042989:sequestering of actin monomers;GO:0014891:striated muscle atrophy;GO:0042246:tissue regeneration;GO:0016192:vesicle-mediated transport;GO:0042060:wound healing;	GO:0030478:actin cap;GO:0015629:actin cytoskeleton;GO:0030864:cortical actin cytoskeleton;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005576:extracellular region;GO:0005615:extracellular space;GO:0030027:lamellipodium;GO:0043209:myelin sheath;GO:0048471:perinuclear region of cytoplasm;GO:0045335:phagocytic vesicle;GO:0005886:plasma membrane;GO:0002102:podosome;GO:0032991:macromolecular complex;GO:0001726:ruffle;GO:0016528:sarcoplasm;	GO:0003779:actin binding;GO:0051015:actin filament binding;GO:0005509:calcium ion binding;GO:0045159:myosin II binding;GO:0036313:phosphatidylinositol 3-kinase catalytic subunit binding;GO:0005546:phosphatidylinositol-4,5-bisphosphate binding;	K05768	;ko04666 Fc gamma R-mediated phagocytosis;ko04810 Regulation of actin cytoskeleton;ko05203 Viral carcinogenesis;
ENSMUSG00000079057	3808	288	3.93	334	4.99	93	1.12	106	1.66	202.244035619555	0.335489283329971	-1.57566141231776	0.261896092181037	-6.01636091319978	1.78381625698198e-09	1.05203994171391e-07	Down	8	45757981	45786253	-	Cyp4v3	cytochrome P450%2C family 4%2C subfamily v%2C polypeptide 3 [Source:MGI Symbol%3BAcc:MGI:2142763]	GO:0010430:fatty acid omega-oxidation;	GO:0005789:endoplasmic reticulum membrane;GO:0016021:integral component of membrane;	GO:0020037:heme binding;GO:0005506:iron ion binding;GO:0004497:monooxygenase activity;	K07427	-
ENSMUSG00000022899	7361	91	0.64	147	1.14	383	2.39	328	2.65	237.717140657851	3.09245555951051	1.62875286293504	0.270869042589898	6.0130639048369	1.82049228065946e-09	1.06955665255295e-07	Ups	16	36570539	36605324	-	Slc15a2	solute carrier family 15 (H+/peptide transporter)%2C member 2 [Source:MGI Symbol%3BAcc:MGI:1890457]	GO:0042938:dipeptide transport;GO:0045087:innate immune response;GO:0006857:oligopeptide transport;GO:0015835:peptidoglycan transport;GO:0015031:protein transport;GO:0070424:regulation of nucleotide-binding oligomerization domain containing signaling pathway;GO:0070293:renal absorption;GO:0042908:xenobiotic transport;	GO:0016324:apical plasma membrane;GO:0005887:integral component of plasma membrane;GO:0016020:membrane;	GO:0071916:dipeptide transmembrane transporter activity;GO:0015334:high-affinity oligopeptide transporter activity;GO:0015333:peptide:proton symporter activity;	K14637	-
ENSMUSG00000046207	3622	478	6.85	360	5.66	167	2.12	151	2.48	283.112031234476	0.396894421856249	-1.33317280873223	0.221970042074991	-6.00609341814617	1.90046717602976e-09	1.10688356335584e-07	Down	11	68393845	68443524	+	Pik3r6	phosphoinositide-3-kinase regulatory subunit 5 [Source:MGI Symbol%3BAcc:MGI:2144613]	GO:0001525:angiogenesis;GO:0007186:G-protein coupled receptor signaling pathway;GO:0046854:phosphatidylinositol phosphorylation;GO:0045766:positive regulation of angiogenesis;GO:0043406:positive regulation of MAP kinase activity;GO:0045582:positive regulation of T cell differentiation;GO:0042269:regulation of natural killer cell mediated cytotoxicity;	GO:0005737:cytoplasm;GO:0016020:membrane;GO:0005942:phosphatidylinositol 3-kinase complex;GO:0005944:phosphatidylinositol 3-kinase complex, class IB;GO:0005886:plasma membrane;	GO:0046935:1-phosphatidylinositol-3-kinase regulator activity;	-	-
ENSMUSG00000021024	1234	4041	170.01	3301	152.23	8685	323.86	5674	273.84	5356.54484435355	2.01460486898466	1.01049690602078	0.168257739366477	6.00564889214304	1.90568188813057e-09	1.10688356335584e-07	Ups	12	55431007	55465239	+	Psma6	proteasome subunit alpha 6 [Source:MGI Symbol%3BAcc:MGI:1347006]	GO:0051092:positive regulation of NF-kappaB transcription factor activity;GO:0010499:proteasomal ubiquitin-independent protein catabolic process;GO:0043161:proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051603:proteolysis involved in cellular protein catabolic process;GO:0007519:skeletal muscle tissue development;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0030016:myofibril;GO:0016363:nuclear matrix;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0000932:cytoplasmic mRNA processing body;GO:0005844:polysome;GO:0000502:proteasome complex;GO:0005839:proteasome core complex;GO:0019773:proteasome core complex, alpha-subunit complex;GO:0030017:sarcomere;	GO:0004175:endopeptidase activity;GO:0051059:NF-kappaB binding;GO:0003723:RNA binding;	K02730	;ko03050 Proteasome;ko05010 Alzheimer disease;ko05012 Parkinson disease;ko05014 Amyotrophic lateral sclerosis;ko05016 Huntington disease;ko05017 Spinocerebellar ataxia;ko05020 Prion disease;ko05022 Pathways of neurodegeneration - multiple diseases;
ENSMUSG00000040441	4519	74	0.85	70	0.88	342	3.48	171	2.25	161.247443895736	3.62549575190773	1.85817828338051	0.309611177031591	6.00165117162715	1.95320971151778e-09	1.12723722702037e-07	Ups	10	127007262	127016514	-	Slc26a10	solute carrier family 26%2C member 10 [Source:MGI Symbol%3BAcc:MGI:2143920]	-	GO:0016323:basolateral plasma membrane;GO:0005887:integral component of plasma membrane;	GO:0015301:anion:anion antiporter activity;GO:0015106:bicarbonate transmembrane transporter activity;GO:0015108:chloride transmembrane transporter activity;GO:0019531:oxalate transmembrane transporter activity;GO:0008271:secondary active sulfate transmembrane transporter activity;GO:0015116:sulfate transmembrane transporter activity;	K14707	-
ENSMUSG00000053063	5528	241	2.26	196	2.02	74	0.62	59	0.64	139.232429765327	0.31658935277397	-1.65931535791665	0.276484957692893	-6.00146703011504	1.95542651876496e-09	1.12723722702037e-07	Down	6	129319654	129342266	+	Clec12a	C-type lectin domain family 12%2C member a [Source:MGI Symbol%3BAcc:MGI:3040968]	GO:0050776:regulation of immune response;	GO:0009986:cell surface;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0030246:carbohydrate binding;GO:0019903:protein phosphatase binding;GO:0030545:receptor regulator activity;	K17516	-
ENSMUSG00000024268	8583	19	0.11	16	0.11	102	0.55	94	0.65	58.1517413820063	5.85187131834914	2.54889804520765	0.425911602987058	5.98457057129084	2.16961506366205e-09	1.24137602187291e-07	Ups	18	25610689	25887214	-	Celf4	CUGBP%2C Elav-like family member 4 [Source:MGI Symbol%3BAcc:MGI:1932407]	GO:0006397:mRNA processing;GO:0048026:positive regulation of mRNA splicing, via spliceosome;GO:0008380:RNA splicing;GO:0000380:alternative mRNA splicing, via spliceosome;GO:0001701:in utero embryonic development;GO:0006376:mRNA splice site selection;GO:0090394:negative regulation of excitatory postsynaptic membrane potential;GO:0048025:negative regulation of mRNA splicing, via spliceosome;GO:0000381:regulation of alternative mRNA splicing, via spliceosome;GO:1902866:regulation of retina development in camera-type eye;	GO:0005737:cytoplasm;GO:0005634:nucleus;GO:0005654:nucleoplasm;	GO:0003723:RNA binding;GO:0042835:BRE binding;GO:0003729:mRNA binding;GO:0036002:pre-mRNA binding;	K13207	-
ENSMUSG00000029821	12742	203	0.83	173	0.77	537	1.94	353	1.65	312.990982678	2.43947372398813	1.2865699438189	0.215206213211451	5.97831226440838	2.25461242417586e-09	1.27614570795687e-07	Ups	6	50165868	50240842	-	Gsdme	gasdermin E [Source:MGI Symbol%3BAcc:MGI:1889850]	GO:0008219:cell death;GO:0071356:cellular response to tumor necrosis factor;GO:0098586:cellular response to virus;GO:0060113:inner ear receptor cell differentiation;GO:0070265:necrotic cell death;GO:0008285:negative regulation of cell proliferation;GO:0002839:positive regulation of immune response to tumor cell;GO:2001244:positive regulation of intrinsic apoptotic signaling pathway;GO:0043410:positive regulation of MAPK cascade;GO:0070269:pyroptosis;GO:0007605:sensory perception of sound;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0016021:integral component of membrane;GO:0016020:membrane;GO:0005886:plasma membrane;	GO:1901612:cardiolipin binding;GO:0005546:phosphatidylinositol-4,5-bisphosphate binding;GO:0022829:wide pore channel activity;	-	-
ENSMUSG00000015189	4037	1543	19.84	1506	21.23	708	8.07	739	10.90	1108.76122251134	0.498194694974523	-1.00521843576284	0.168158928800701	-5.97778805402722	2.26187744268336e-09	1.27614570795687e-07	Down	6	4600839	4643355	+	Casd1	CAS1 domain containing 1 [Source:MGI Symbol%3BAcc:MGI:2384865]	GO:0005975:carbohydrate metabolic process;	GO:0030173:integral component of Golgi membrane;	GO:0047186:N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity;	-	-
ENSMUSG00000067148	2278	1688	38.47	1457	36.40	3842	77.61	2403	62.82	2315.40172167475	2.04004759117751	1.02860280844918	0.172147842831894	5.97511296992338	2.29930792080616e-09	1.29148672738614e-07	Ups	17	46554846	46558980	-	Polr1c	polymerase (RNA) I polypeptide C [Source:MGI Symbol%3BAcc:MGI:103288]	-	GO:0005654:nucleoplasm;GO:0005736:DNA-directed RNA polymerase I complex;GO:0005666:DNA-directed RNA polymerase III complex;	GO:0003677:DNA binding;GO:0046983:protein dimerization activity;GO:0001054:RNA polymerase I activity;GO:0001056:RNA polymerase III activity;	K03027	;ko03020 RNA polymerase;ko04623 Cytosolic DNA-sensing pathway;
ENSMUSG00000038264	3298	1879	29.58	1626	28.06	4928	68.76	2751	49.68	2749.33524564494	2.23889423990596	1.16278638028212	0.194642996998106	5.97394408334885	2.31585207058515e-09	1.29603195804207e-07	Ups	9	57847395	57870148	+	Sema7a	sema domain%2C immunoglobulin domain (Ig)%2C and GPI membrane anchor%2C (semaphorin) 7A [Source:MGI Symbol%3BAcc:MGI:1306826]	GO:0048675:axon extension;GO:0007411:axon guidance;GO:0006954:inflammatory response;GO:0007229:integrin-mediated signaling pathway;GO:0050919:negative chemotaxis;GO:0048843:negative regulation of axon extension involved in axon guidance;GO:0001755:neural crest cell migration;GO:0031175:neuron projection development;GO:0021988:olfactory lobe development;GO:0045773:positive regulation of axon extension;GO:0030335:positive regulation of cell migration;GO:0070374:positive regulation of ERK1 and ERK2 cascade;GO:0060907:positive regulation of macrophage cytokine production;GO:0001934:positive regulation of protein phosphorylation;GO:0050727:regulation of inflammatory response;GO:0071526:semaphorin-plexin signaling pathway;	GO:0031225:anchored component of membrane;GO:0009897:external side of plasma membrane;GO:0005615:extracellular space;GO:0005887:integral component of plasma membrane;GO:0005886:plasma membrane;	GO:0045499:chemorepellent activity;GO:0005178:integrin binding;GO:0030215:semaphorin receptor binding;	K06529	;ko04360 Axon guidance;
ENSMUSG00000025212	3110	259	4.32	290	5.31	108	1.60	79	1.51	180.333952788493	0.351924892250262	-1.50666053290003	0.25244969427209	-5.96816144794436	2.3994189056808e-09	1.33482950983637e-07	Down	19	45035942	45044822	+	Sfxn3	sideroflexin 3 [Source:MGI Symbol%3BAcc:MGI:2137679]	GO:1990542:mitochondrial transmembrane transport;GO:0006730:one-carbon metabolic process;	GO:0031305:integral component of mitochondrial inner membrane;GO:0031966:mitochondrial membrane;GO:0005739:mitochondrion;GO:0016021:integral component of membrane;	GO:0022889:serine transmembrane transporter activity;GO:0022857:transmembrane transporter activity;	-	-
ENSMUSG00000020142	3926	283	3.74	351	5.09	115	1.35	102	1.55	209.246980676633	0.355470881415915	-1.49219670932513	0.250035223487285	-5.96794598982178	2.40258865732906e-09	1.33482950983637e-07	Down	11	20252180	20282713	-	Slc1a4	solute carrier family 1 (glutamate/neutral amino acid transporter)%2C member 4 [Source:MGI Symbol%3BAcc:MGI:2135601]	GO:0050890:cognition;GO:0034589:hydroxyproline transport;GO:1904273:L-alanine import across plasma membrane;GO:0015808:L-alanine transport;GO:1903812:L-serine import into cell;GO:0015825:L-serine transport;GO:0015824:proline transport;GO:0098718:serine import across plasma membrane;GO:0015826:threonine transport;	GO:0005813:centrosome;GO:0030425:dendrite;GO:0016021:integral component of membrane;GO:0005882:intermediate filament;GO:0042470:melanosome;GO:0016020:membrane;GO:0043025:neuronal cell body;GO:0005886:plasma membrane;	GO:0005254:chloride channel activity;GO:0015180:L-alanine transmembrane transporter activity;GO:0015183:L-aspartate transmembrane transporter activity;GO:0015184:L-cystine transmembrane transporter activity;GO:0034590:L-hydroxyproline transmembrane transporter activity;GO:0015193:L-proline transmembrane transporter activity;GO:0015194:L-serine transmembrane transporter activity;GO:0015195:L-threonine transmembrane transporter activity;GO:0015175:neutral amino acid transmembrane transporter activity;GO:0015293:symporter activity;	K05615	-
ENSMUSG00000098234	4219	484	5.96	448	6.04	1268	13.83	759	10.71	729.212103496944	2.22898720477657	1.15638833501024	0.19386773466595	5.96483131658186	2.44886893659386e-09	1.35563019038737e-07	Ups	1	9926809	10014398	-	Snhg6	small nucleolar RNA host gene 6 [Source:MGI Symbol%3BAcc:MGI:1921074]	-	-	-	-	-
ENSMUSG00000018446	2826	3600	66.13	2952	59.44	8029	130.73	5051	106.45	4840.78666522375	2.05270791314149	1.03752835601859	0.1744266725005	5.94822076890572	2.71072827613132e-09	1.49519091317258e-07	Ups	11	70868662	70873852	-	C1qbp	complement component 1%2C q subcomponent binding protein [Source:MGI Symbol%3BAcc:MGI:1194505]	GO:0006915:apoptotic process;GO:0006958:complement activation, classical pathway;GO:0045087:innate immune response;GO:0042256:mature ribosome assembly;GO:0006397:mRNA processing;GO:0050687:negative regulation of defense response to virus;GO:0032689:negative regulation of interferon-gamma production;GO:0032695:negative regulation of interleukin-12 production;GO:0039534:negative regulation of MDA-5 signaling pathway;GO:0048025:negative regulation of mRNA splicing, via spliceosome;GO:0039536:negative regulation of RIG-I signaling pathway;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0014065:phosphatidylinositol 3-kinase signaling;GO:0043065:positive regulation of apoptotic process;GO:0045785:positive regulation of cell adhesion;GO:2000510:positive regulation of dendritic cell chemotaxis;GO:0070131:positive regulation of mitochondrial translation;GO:0090023:positive regulation of neutrophil chemotaxis;GO:0051897:positive regulation of protein kinase B signaling;GO:1900026:positive regulation of substrate adhesion-dependent cell spreading;GO:1901165:positive regulation of trophoblast cell migration;GO:0030449:regulation of complement activation;GO:0008380:RNA splicing;GO:0006955:immune response;	GO:0009986:cell surface;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005615:extracellular space;GO:0016020:membrane;GO:0005759:mitochondrial matrix;GO:0005739:mitochondrion;GO:0005730:nucleolus;GO:0005634:nucleus;GO:0005886:plasma membrane;GO:0098793:presynapse;GO:0048786:presynaptic active zone;	GO:0031690:adrenergic receptor binding;GO:0001849:complement component C1q binding;GO:0005540:hyaluronic acid binding;GO:0030984:kininogen binding;GO:0097177:mitochondrial ribosome binding;GO:0003729:mRNA binding;GO:0005080:protein kinase C binding;GO:0003714:transcription corepressor activity;GO:0008494:translation activator activity;	K15414	-
ENSMUSG00000051890	3137	174	2.88	175	3.17	46	0.67	47	0.89	108.404792174176	0.278514293118433	-1.84417672753047	0.310122181961178	-5.94661341497118	2.73746886142299e-09	1.50452858498423e-07	Down	12	69287950	69331406	+	Klhdc1	kelch domain containing 1 [Source:MGI Symbol%3BAcc:MGI:2672853]	-	GO:0031466:Cul5-RING ubiquitin ligase complex;GO:0005737:cytoplasm;GO:0005829:cytosol;	-	-	-
ENSMUSG00000039001	810	2956	189.46	2831	198.89	7825	444.53	4463	328.15	4447.69686918582	2.16882947110096	1.11691662245754	0.187915888064131	5.94370510106289	2.78650712031246e-09	1.52601072081683e-07	Ups	2	179899170	179900238	+	Rps21	ribosomal protein S21 [Source:MGI Symbol%3BAcc:MGI:1913731]	GO:0002181:cytoplasmic translation;GO:0000447:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000461:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);	GO:0005829:cytosol;GO:0022626:cytosolic ribosome;GO:0022627:cytosolic small ribosomal subunit;GO:0042788:polysomal ribosome;GO:0005791:rough endoplasmic reticulum;GO:0045202:synapse;	GO:0047485:protein N-terminus binding;GO:0043022:ribosome binding;GO:0003735:structural constituent of ribosome;	K02971	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000024675	1751	4050	120.08	3782	122.91	2240	58.87	1242	42.24	2760.55848458185	0.453875932053849	-1.1396301072222	0.192528245194029	-5.91928787422171	3.23338576960466e-09	1.75368032726433e-07	Down	19	11382134	11404610	+	Ms4a4c	membrane-spanning 4-domains%2C subfamily A%2C member 4C [Source:MGI Symbol%3BAcc:MGI:1927656]	-	GO:0016021:integral component of membrane;	-	-	-
ENSMUSG00000005125	6596	514	4.05	493	4.25	257	1.79	183	1.65	354.411297248616	0.451651674894773	-1.1467175360363	0.193730844320532	-5.91912733389544	3.23654318909485e-09	1.75368032726433e-07	Down	15	66801167	66841489	-	Ndrg1	N-myc downstream regulated gene 1 [Source:MGI Symbol%3BAcc:MGI:1341799]	GO:0071456:cellular response to hypoxia;GO:0030330:DNA damage response, signal transduction by p53 class mediator;GO:0045576:mast cell activation;GO:0008285:negative regulation of cell proliferation;GO:0032287:peripheral nervous system myelin maintenance;GO:0007165:signal transduction;	GO:0005912:adherens junction;GO:0005813:centrosome;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005874:microtubule;GO:0015630:microtubule cytoskeleton;GO:0043209:myelin sheath;GO:0005634:nucleus;GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;GO:0055038:recycling endosome membrane;	GO:0045296:cadherin binding;GO:0043015:gamma-tubulin binding;GO:0008017:microtubule binding;GO:0031267:small GTPase binding;	K18266	-
ENSMUSG00000037855	5205	14	0.14	15	0.16	108	0.95	74	0.85	52.5195337552162	6.46932396936604	2.69361496152226	0.455793524316651	5.90972626379603	3.42676692893602e-09	1.85021282001074e-07	Ups	10	67721933	67748492	-	Zfp365	zinc finger protein 365 [Source:MGI Symbol%3BAcc:MGI:2143676]	GO:0021687:cerebellar molecular layer morphogenesis;GO:0060997:dendritic spine morphogenesis;GO:0033566:gamma-tubulin complex localization;GO:0000281:mitotic cytokinesis;GO:0010977:negative regulation of neuron projection development;GO:0048714:positive regulation of oligodendrocyte differentiation;GO:0010569:regulation of double-strand break repair via homologous recombination;GO:0000723:telomere maintenance;	GO:0034451:centriolar satellite;GO:0005813:centrosome;GO:0005737:cytoplasm;GO:0043231:intracellular membrane-bounded organelle;	GO:0042802:identical protein binding;GO:0046872:metal ion binding;GO:0042803:protein homodimerization activity;	K16737	-
ENSMUSG00000050965	8992	5169	29.84	4222	26.72	1808	9.25	2179	14.43	3296.54508375548	0.450161393035331	-1.15148576191761	0.195393469985646	-5.89316399366983	3.7887006113245e-09	2.01721997132118e-07	Down	11	107824213	108234754	-	Prkca	protein kinase C%2C alpha [Source:MGI Symbol%3BAcc:MGI:97595]	GO:0007568:aging;GO:0001525:angiogenesis;GO:0007155:cell adhesion;GO:0006874:cellular calcium ion homeostasis;GO:0097190:apoptotic signaling pathway;GO:0002159:desmosome assembly;GO:0035408:histone H3-T6 phosphorylation;GO:0035556:intracellular signal transduction;GO:0007077:mitotic nuclear envelope disassembly;GO:0034351:negative regulation of glial cell apoptotic process;GO:0018105:peptidyl-serine phosphorylation;GO:0018107:peptidyl-threonine phosphorylation;GO:0045766:positive regulation of angiogenesis;GO:0043536:positive regulation of blood vessel endothelial cell migration;GO:0045780:positive regulation of bone resorption;GO:0010613:positive regulation of cardiac muscle hypertrophy;GO:0045785:positive regulation of cell adhesion;GO:0030335:positive regulation of cell migration;GO:2000707:positive regulation of dense core granule biogenesis;GO:0010595:positive regulation of endothelial cell migration;GO:0001938:positive regulation of endothelial cell proliferation;GO:0070374:positive regulation of ERK1 and ERK2 cascade;GO:0031666:positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0045651:positive regulation of macrophage differentiation;GO:0045931:positive regulation of mitotic cell cycle;GO:0006468:protein phosphorylation;GO:0043488:regulation of mRNA stability;GO:0090330:regulation of platelet aggregation;GO:0070555:response to interleukin-1;	GO:0035866:alphav-beta3 integrin-PKCalpha complex;GO:0045177:apical part of cell;GO:0030424:axon;GO:0044305:calyx of Held;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005783:endoplasmic reticulum;GO:0070062:extracellular exosome;GO:0031966:mitochondrial membrane;GO:0005739:mitochondrion;GO:0005654:nucleoplasm;GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;	GO:0005524:ATP binding;GO:0004698:calcium-dependent protein kinase C activity;GO:0019899:enzyme binding;GO:0035403:histone kinase activity (H3-T6 specific);GO:0005178:integrin binding;GO:0004672:protein kinase activity;GO:0004697:protein kinase C activity;GO:0004674:protein serine/threonine kinase activity;GO:0008270:zinc ion binding;	K02677	;ko01521 EGFR tyrosine kinase inhibitor resistance;ko04010 MAPK signaling pathway;ko04011 MAPK signaling pathway - yeast;ko04012 ErbB signaling pathway;ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04020 Calcium signaling pathway;ko04066 HIF-1 signaling pathway;ko04070 Phosphatidylinositol signaling system;ko04071 Sphingolipid signaling pathway;ko04072 Phospholipase D signaling pathway;ko04139 Mitophagy - yeast;ko04150 mTOR signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04261 Adrenergic signaling in cardiomyocytes;ko04270 Vascular smooth muscle contraction;ko04310 Wnt signaling pathway;ko04360 Axon guidance;ko04370 VEGF signaling pathway;ko04510 Focal adhesion;ko04540 Gap junction;ko04613 Neutrophil extracellular trap formation;ko04650 Natural killer cell mediated cytotoxicity;ko04664 Fc epsilon RI signaling pathway;ko04666 Fc gamma R-mediated phagocytosis;ko04670 Leukocyte transendothelial migration;ko04713 Circadian entrainment;ko04720 Long-term potentiation;ko04723 Retrograde endocannabinoid signaling;ko04724 Glutamatergic synapse;ko04725 Cholinergic synapse;ko04726 Serotonergic synapse;ko04727 GABAergic synapse;ko04728 Dopaminergic synapse;ko04730 Long-term depression;ko04745 Phototransduction - fly;ko04750 Inflammatory mediator regulation of TRP channels;ko04911 Insulin secretion;ko04912 GnRH signaling pathway;ko04916 Melanogenesis;ko04918 Thyroid hormone synthesis;ko04919 Thyroid hormone signaling pathway;ko04921 Oxytocin signaling pathway;ko04925 Aldosterone synthesis and secretion;ko04926 Relaxin signaling pathway;ko04928 Parathyroid hormone synthesis, secretion and action;ko04929 GnRH secretion;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko04935 Growth hormone synthesis, secretion and action;ko04960 Aldosterone-regulated sodium reabsorption;ko04961 Endocrine and other factor-regulated calcium reabsorption;ko04970 Salivary secretion;ko04971 Gastric acid secretion;ko04972 Pancreatic secretion;ko05017 Spinocerebellar ataxia;ko05022 Pathways of neurodegeneration - multiple diseases;ko05031 Amphetamine addiction;ko05032 Morphine addiction;ko05110 Vibrio cholerae infection;ko05143 African trypanosomiasis;ko05146 Amoebiasis;ko05161 Hepatitis B;ko05163 Human cytomegalovirus infection;ko05164 Influenza A;ko05170 Human immunodeficiency virus 1 infection;ko05171 Coronavirus disease - COVID-19;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05206 MicroRNAs in cancer;ko05214 Glioma;ko05223 Non-small cell lung cancer;ko05225 Hepatocellular carcinoma;ko05231 Choline metabolism in cancer;
ENSMUSG00000030084	9054	112	0.64	100	0.63	307	1.56	235	1.55	187.517020015147	2.65081141184486	1.40643403539787	0.239023716624448	5.88407734286737	4.00280635890495e-09	2.11651836922236e-07	Ups	6	89293296	89339602	-	Plxna1	plexin A1 [Source:MGI Symbol%3BAcc:MGI:107685]	GO:0060666:dichotomous subdivision of terminal units involved in salivary gland branching;GO:0007162:negative regulation of cell adhesion;GO:1990138:neuron projection extension;GO:0097485:neuron projection guidance;GO:0050772:positive regulation of axonogenesis;GO:0030334:regulation of cell migration;GO:0008360:regulation of cell shape;GO:0043087:regulation of GTPase activity;GO:0014910:regulation of smooth muscle cell migration;GO:1902287:semaphorin-plexin signaling pathway involved in axon guidance;	GO:0005829:cytosol;GO:0005887:integral component of plasma membrane;GO:0016020:membrane;GO:0005654:nucleoplasm;GO:0005886:plasma membrane;GO:0002116:semaphorin receptor complex;	GO:0017154:semaphorin receptor activity;	K06820	;ko04360 Axon guidance;
ENSMUSG00000027589	4183	1111	13.79	1396	18.99	494	5.43	541	7.70	874.973619019894	0.432851020790045	-1.20805753310133	0.205352662455476	-5.88284329336739	4.03277720157274e-09	2.12503799343355e-07	Down	2	181479647	181499254	+	Pcmtd2	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 [Source:MGI Symbol%3BAcc:MGI:1923927]	-	GO:0005737:cytoplasm;	GO:0004719:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity;	-	-
ENSMUSG00000034271	2148	86	2.08	60	1.59	218	4.67	239	6.63	152.06482008971	3.30322297250318	1.72387435698867	0.293111774213014	5.88128662390707	4.07089503972386e-09	2.13777755270978e-07	Ups	12	85645801	85686652	+	Jdp2	Jun dimerization protein 2 [Source:MGI Symbol%3BAcc:MGI:1932093]	GO:0045599:negative regulation of fat cell differentiation;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0031065:positive regulation of histone deacetylation;GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005634:nucleus;	GO:0003682:chromatin binding;GO:0003677:DNA binding;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001227:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003690:double-stranded DNA binding;GO:0044877:macromolecular complex binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K09033	-
ENSMUSG00000120896	883	90	5.29	114	7.35	313	16.31	240	16.19	188.596662087513	2.80088033298256	1.48588034588988	0.253881194882974	5.85266012543699	4.83772099827914e-09	2.51463097585127e-07	Ups	7	126027591	126028473	-	-	novel transcript	-	-	-	-	-
ENSMUSG00000052751	3975	160	2.09	147	2.10	441	5.11	294	4.40	257.8306321795	2.46719088285884	1.30286933910803	0.223632786156482	5.82593170482784	5.67948400855317e-09	2.94220296578224e-07	Ups	6	48570817	48576016	+	Repin1	replication initiator 1 [Source:MGI Symbol%3BAcc:MGI:1889817]	GO:0006260:DNA replication;GO:0046326:positive regulation of glucose import;GO:2000191:regulation of fatty acid transport;GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005694:chromosome;GO:0005829:cytosol;GO:0022626:cytosolic ribosome;GO:0005811:lipid particle;GO:0031965:nuclear membrane;GO:0005654:nucleoplasm;	GO:0043035:chromatin insulator sequence binding;GO:0046872:metal ion binding;	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000030214	2633	338	6.66	324	7.00	144	2.52	118	2.67	226.610869338142	0.411217416422169	-1.28202672613916	0.220165143090408	-5.82302315499918	5.77925445784834e-09	2.98380767194096e-07	Down	6	136589068	136638926	-	Plbd1	phospholipase B domain containing 1 [Source:MGI Symbol%3BAcc:MGI:1914107]	GO:0009395:phospholipid catabolic process;	GO:0005576:extracellular region;GO:0005615:extracellular space;GO:0005764:lysosome;	GO:0004620:phospholipase activity;	-	-
ENSMUSG00000000791	4105	64	0.81	34	0.47	230	2.58	148	2.15	117.745613157344	3.98845289526727	1.99582923938957	0.342998609618702	5.81876772505945	5.92830466853304e-09	3.05049073111697e-07	Ups	8	71261093	71274068	+	Il12rb1	interleukin 12 receptor%2C beta 1 [Source:MGI Symbol%3BAcc:MGI:104579]	GO:0071346:cellular response to interferon-gamma;GO:0019221:cytokine-mediated signaling pathway;GO:0035722:interleukin-12-mediated signaling pathway;GO:0038155:interleukin-23-mediated signaling pathway;GO:0018108:peptidyl-tyrosine phosphorylation;GO:0042104:positive regulation of activated T cell proliferation;GO:0002230:positive regulation of defense response to virus by host;GO:0032729:positive regulation of interferon-gamma production;GO:0002827:positive regulation of T-helper 1 type immune response;	GO:0009897:external side of plasma membrane;GO:0042022:interleukin-12 receptor complex;GO:0072536:interleukin-23 receptor complex;GO:0005886:plasma membrane;GO:0043235:receptor complex;	GO:0004896:cytokine receptor activity;	K05063	;ko04060 Cytokine-cytokine receptor interaction;ko04630 JAK-STAT signaling pathway;ko04658 Th1 and Th2 cell differentiation;ko04659 Th17 cell differentiation;ko05200 Pathways in cancer;ko05321 Inflammatory bowel disease;
ENSMUSG00000052713	8513	1384	8.44	1457	9.74	612	3.31	677	4.74	1019.66378876325	0.477044439933152	-1.06780442554381	0.183599127338401	-5.81595588728309	6.0288364985591e-09	3.09184544712058e-07	Down	18	55021120	55125627	-	Zfp608	zinc finger protein 608 [Source:MGI Symbol%3BAcc:MGI:2442338]	GO:0033085:negative regulation of T cell differentiation in thymus;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005634:nucleus;	GO:0046872:metal ion binding;	-	-
ENSMUSG00000034266	1406	925	34.15	916	37.07	2232	73.05	1395	59.09	1349.08047083705	2.02069727080611	1.01485320166792	0.175068778130673	5.79688287371507	6.75588393032132e-09	3.41896779496855e-07	Ups	12	85733443	85755861	+	Batf	basic leucine zipper transcription factor%2C ATF-like [Source:MGI Symbol%3BAcc:MGI:1859147]	GO:0006974:cellular response to DNA damage stimulus;GO:0042832:defense response to protozoan;GO:0030330:DNA damage response, signal transduction by p53 class mediator;GO:0060218:hematopoietic stem cell differentiation;GO:0045190:isotype switching;GO:0002320:lymphoid progenitor cell differentiation;GO:0043011:myeloid dendritic cell differentiation;GO:0001819:positive regulation of cytokine production;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0072539:T-helper 17 cell differentiation;GO:0072540:T-helper 17 cell lineage commitment;GO:0045064:T-helper 2 cell differentiation;	GO:0005737:cytoplasm;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043565:sequence-specific DNA binding;	K09034	;ko05235 PD-L1 expression and PD-1 checkpoint pathway in cancer;
ENSMUSG00000022878	1381	47	1.77	68	2.80	234	7.80	160	6.90	126.490241140032	3.51915956580093	1.81523093027702	0.31318824930441	5.79597393678928	6.79258129341116e-09	3.42623163003838e-07	Ups	16	22965286	22976778	+	Adipoq	adiponectin%2C C1Q and collagen domain containing [Source:MGI Symbol%3BAcc:MGI:106675]	GO:0050873:brown fat cell differentiation;GO:0071320:cellular response to cAMP;GO:0035690:cellular response to drug;GO:0071872:cellular response to epinephrine stimulus;	GO:0071944:cell periphery;GO:0009986:cell surface;GO:0005581:collagen trimer;GO:0005783:endoplasmic reticulum;	GO:0005179:hormone activity;GO:0042802:identical protein binding;GO:0042803:protein homodimerization activity;GO:0033691:sialic acid binding;	K07296	;ko03320 PPAR signaling pathway;ko04152 AMPK signaling pathway;ko04211 Longevity regulating pathway;ko04920 Adipocytokine signaling pathway;ko04930 Type II diabetes mellitus;ko04932 Non-alcoholic fatty liver disease;
ENSMUSG00000015305	8568	265	1.61	234	1.55	74	0.40	85	0.59	161.633827610375	0.335148191984688	-1.57712894389145	0.272133790531464	-5.79541754374345	6.81514065279900e-09	3.42633989409901e-07	Down	10	8597983	8761814	-	Sash1	SAM and SH3 domain containing 1 [Source:MGI Symbol%3BAcc:MGI:1917347]	GO:0045766:positive regulation of angiogenesis;GO:0010595:positive regulation of endothelial cell migration;GO:0043507:positive regulation of JUN kinase activity;GO:0031666:positive regulation of lipopolysaccharide-mediated signaling pathway;GO:1901224:positive regulation of NIK/NF-kappaB signaling;GO:1900745:positive regulation of p38MAPK cascade;GO:0000209:protein polyubiquitination;GO:0010632:regulation of epithelial cell migration;GO:1902498:regulation of protein autoubiquitination;GO:1900044:regulation of protein K63-linked ubiquitination;	GO:0005737:cytoplasm;GO:0016020:membrane;GO:0032991:macromolecular complex;	GO:0001965:G-protein alpha-subunit binding;GO:0031435:mitogen-activated protein kinase kinase kinase binding;GO:0060090:binding, bridging;GO:0008022:protein C-terminus binding;GO:0019901:protein kinase binding;	-	-
ENSMUSG00000029075	1365	113	4.30	106	4.42	287	9.68	257	11.21	190.794540131595	2.59094929548087	1.37348078245198	0.23704669460239	5.79413598133392	6.86738009545521e-09	3.44132047005589e-07	Ups	4	156098300	156101069	+	Tnfrsf4	tumor necrosis factor receptor superfamily%2C member 4 [Source:MGI Symbol%3BAcc:MGI:104512]	GO:0006968:cellular defense response;GO:0006954:inflammatory response;GO:0070236:negative regulation of activation-induced cell death of T cells;GO:0001818:negative regulation of cytokine production;GO:0043433:negative regulation of sequence-specific DNA binding transcription factor activity;GO:2001237:negative regulation of extrinsic apoptotic signaling pathway;GO:0045892:negative regulation of transcription, DNA-templated;GO:0030890:positive regulation of B cell proliferation;GO:0002639:positive regulation of immunoglobulin production;GO:0042981:regulation of apoptotic process;GO:0045859:regulation of protein kinase activity;GO:0042098:T cell proliferation;	GO:0009986:cell surface;GO:0009897:external side of plasma membrane;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0005031:tumor necrosis factor-activated receptor activity;	K05142	;ko04060 Cytokine-cytokine receptor interaction;
ENSMUSG00000027858	4755	815	8.90	784	9.38	342	3.31	371	4.65	570.038235463586	0.468612495251181	-1.09353267163686	0.188830112249371	-5.79109263141637	6.99299936366529e-09	3.4928551219037e-07	Down	3	102641845	102708829	+	Tspan2	tetraspanin 2 [Source:MGI Symbol%3BAcc:MGI:1917997]	GO:0014002:astrocyte development;GO:0061564:axon development;GO:0007420:brain development;GO:0006954:inflammatory response;GO:0014005:microglia development;GO:0042552:myelination;GO:0048709:oligodendrocyte differentiation;	GO:0005887:integral component of plasma membrane;GO:0043209:myelin sheath;GO:0005654:nucleoplasm;GO:0005886:plasma membrane;	-	K17354	-
ENSMUSG00000057246	4073	178	2.27	120	1.68	39	0.44	29	0.42	88.9887923248491	0.237449508171269	-2.07430732693961	0.358662765943606	-5.78344763912784	7.31849746593113e-09	3.62005935943832e-07	Down	17	34617794	34679708	+	BC051142	cDNA sequence BC051142 [Source:MGI Symbol%3BAcc:MGI:3039565]	-	GO:0016021:integral component of membrane;GO:0005634:nucleus;	-	-	-
ENSMUSG00000028766	4033	266	3.42	169	2.38	676	7.71	430	6.35	380.287063657416	2.62463660196119	1.39211768607733	0.240748996084211	5.78244440774482	7.36229027656614e-09	3.63001154665161e-07	Ups	4	137469044	137523695	-	Alpl	alkaline phosphatase%2C liver/bone/kidney [Source:MGI Symbol%3BAcc:MGI:87983]	GO:0071407:cellular response to organic cyclic compound;GO:0071529:cementum mineralization;GO:0016311:dephosphorylation;GO:0003006:developmental process involved in reproduction;GO:0001958:endochondral ossification;GO:0046677:response to antibiotic;GO:0051384:response to glucocorticoid;GO:0032496:response to lipopolysaccharide;GO:0033280:response to vitamin D;	GO:0031225:anchored component of membrane;GO:0031012:extracellular matrix;GO:0065010:extracellular membrane-bounded organelle;GO:0005615:extracellular space;GO:0005886:plasma membrane;	GO:0004035:alkaline phosphatase activity;GO:0046872:metal ion binding;GO:0016462:pyrophosphatase activity;	K01077	;ko00730 Thiamine metabolism;ko00790 Folate biosynthesis;ko01100 Metabolic pathways;ko01240 Biosynthesis of cofactors;ko02020 Two-component system;
ENSMUSG00000031803	3055	41	0.70	44	0.82	189	2.85	122	2.38	98.1375011160866	3.7612006139351	1.91119325852141	0.330875075188164	5.77617778381927	7.64166302036952e-09	3.75568143443417e-07	Ups	8	72143400	72154433	-	B3gnt3	UDP-GlcNAc:betaGal beta-1%2C3-N-acetylglucosaminyltransferase 3 [Source:MGI Symbol%3BAcc:MGI:2152535]	GO:0030311:poly-N-acetyllactosamine biosynthetic process;GO:0006486:protein glycosylation;	GO:0005794:Golgi apparatus;GO:0000139:Golgi membrane;GO:0016021:integral component of membrane;	GO:0008376:acetylgalactosaminyltransferase activity;GO:0008375:acetylglucosaminyltransferase activity;GO:0047223:beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity;GO:0008457:beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity;GO:0008532:N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity;	K07970	;ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series;ko01100 Metabolic pathways;
ENSMUSG00000039013	2790	174	3.24	107	2.18	29	0.48	28	0.60	82.2236275981575	0.212907718503299	-2.23169984239831	0.386532499493933	-5.77364088484193	7.75766841661625e-09	3.80051397764836e-07	Down	7	43000765	43008955	+	Siglecf	sialic acid binding Ig-like lectin F [Source:MGI Symbol%3BAcc:MGI:2681107]	GO:0007155:cell adhesion;GO:0030100:regulation of endocytosis;	GO:0016021:integral component of membrane;GO:0005764:lysosome;GO:0005886:plasma membrane;	GO:0048029:monosaccharide binding;GO:0033691:sialic acid binding;	K06549	-
ENSMUSG00000028042	5591	407	3.78	455	4.63	194	1.60	90	0.96	279.255164518462	0.334381802913018	-1.58043175692274	0.273968029043218	-5.76867221493726	7.98985375701899e-09	3.90179673599137e-07	Down	3	89284951	89302083	-	Zbtb7b	zinc finger and BTB domain containing 7B [Source:MGI Symbol%3BAcc:MGI:102755]	GO:0007595:lactation;GO:0043377:negative regulation of CD8-positive, alpha-beta T cell differentiation;GO:0010629:negative regulation of gene expression;GO:0051141:negative regulation of NK T cell proliferation;GO:2000320:negative regulation of T-helper 17 cell differentiation;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0001865:NK T cell differentiation;GO:0090336:positive regulation of brown fat cell differentiation;GO:0043372:positive regulation of CD4-positive, alpha-beta T cell differentiation;GO:0010628:positive regulation of gene expression;GO:0031065:positive regulation of histone deacetylation;GO:0046628:positive regulation of insulin receptor signaling pathway;GO:0032740:positive regulation of interleukin-17 production;GO:2000640:positive regulation of SREBP signaling pathway;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0043370:regulation of CD4-positive, alpha-beta T cell differentiation;GO:0043376:regulation of CD8-positive, alpha-beta T cell differentiation;GO:0010468:regulation of gene expression;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0032868:response to insulin;GO:0007398:ectoderm development;GO:0006366:transcription from RNA polymerase II promoter;	GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0000987:core promoter proximal region sequence-specific DNA binding;GO:0003677:DNA binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0042826:histone deacetylase binding;GO:0042802:identical protein binding;GO:0046872:metal ion binding;GO:0042803:protein homodimerization activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K10494	-
ENSMUSG00000113211	3750	107	1.48	206	3.13	34	0.42	22	0.35	90.6037277085063	0.182959560786724	-2.45040328735907	0.425006181874545	-5.76557093017153	8.1381865368735e-09	3.96161753512439e-07	Down	13	52250777	52278197	+	4921525O09Rik	RIKEN cDNA 4921525O09 gene [Source:MGI Symbol%3BAcc:MGI:1921300]	-	-	-	-	-
ENSMUSG00000030123	7301	1440	10.24	992	7.73	2694	16.98	2088	17.03	1789.11173973934	2.04645923227443	1.03312992699046	0.179254596691165	5.76347801429282	8.23979912456416e-09	3.98577538725763e-07	Ups	6	115931772	115971966	-	Plxnd1	plexin D1 [Source:MGI Symbol%3BAcc:MGI:2154244]	GO:0001525:angiogenesis;GO:0035904:aorta development;GO:0001569:patterning of blood vessels;GO:0003279:cardiac septum development;GO:0060976:coronary vasculature development;GO:0060666:dichotomous subdivision of terminal units involved in salivary gland branching;GO:0043542:endothelial cell migration;GO:0001822:kidney development;GO:0007162:negative regulation of cell adhesion;GO:0003151:outflow tract morphogenesis;GO:0050772:positive regulation of axonogenesis;GO:0032092:positive regulation of protein binding;GO:0045765:regulation of angiogenesis;GO:0030334:regulation of cell migration;GO:0008360:regulation of cell shape;GO:0043087:regulation of GTPase activity;GO:0071526:semaphorin-plexin signaling pathway;GO:1902287:semaphorin-plexin signaling pathway involved in axon guidance;GO:0007416:synapse assembly;	GO:0005887:integral component of plasma membrane;GO:0030027:lamellipodium;GO:0031258:lamellipodium membrane;GO:0005886:plasma membrane;GO:0002116:semaphorin receptor complex;	GO:0019904:protein domain specific binding;GO:0017154:semaphorin receptor activity;	K06822	-
ENSMUSG00000033502	12456	1420	5.92	1290	5.89	605	2.24	661	3.16	980.400786457415	0.491842650333459	-1.02373125064748	0.178395584173876	-5.73854591406076	9.54928763023949e-09	4.53339865393475e-07	Down	3	116066202	116222394	-	Cdc14a	CDC14 cell division cycle 14A [Source:MGI Symbol%3BAcc:MGI:2442676]	GO:0051301:cell division;GO:0060271:cilium morphogenesis;GO:0000226:microtubule cytoskeleton organization;GO:0000278:mitotic cell cycle;GO:0032467:positive regulation of cytokinesis;GO:0051726:regulation of cell cycle;GO:0007096:regulation of exit from mitosis;GO:0007605:sensory perception of sound;	GO:0005813:centrosome;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:1902636:kinociliary basal body;GO:0060091:kinocilium;GO:0072686:mitotic spindle;GO:0016604:nuclear body;GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0000922:spindle pole;GO:0032426:stereocilium bundle tip;	GO:0004722:protein serine/threonine phosphatase activity;GO:0004725:protein tyrosine phosphatase activity;GO:0008138:protein tyrosine/serine/threonine phosphatase activity;	K06639	;ko04110 Cell cycle;ko04111 Cell cycle - yeast;ko04113 Meiosis - yeast;
ENSMUSG00000022620	3680	306	4.32	309	4.78	139	1.74	86	1.39	205.239167402173	0.376255644909436	-1.41021486830603	0.245927819659807	-5.73426329016693	9.79370953954423e-09	4.63508463207936e-07	Down	15	89356679	89361628	-	Arsa	arylsulfatase A [Source:MGI Symbol%3BAcc:MGI:88077]	GO:0006914:autophagy;GO:0007339:binding of sperm to zona pellucida;GO:0007417:central nervous system development;GO:0043627:response to estrogen;GO:0045471:response to ethanol;GO:0051597:response to methylmercury;GO:0007584:response to nutrient;GO:0009268:response to pH;	GO:0001669:acrosomal vesicle;GO:0005737:cytoplasm;GO:0005783:endoplasmic reticulum;GO:0005768:endosome;GO:0005615:extracellular space;GO:0031232:extrinsic component of external side of plasma membrane;GO:0016021:integral component of membrane;GO:0005764:lysosome;GO:0005886:plasma membrane;	GO:0004065:arylsulfatase activity;GO:0005509:calcium ion binding;GO:0004098:cerebroside-sulfatase activity;GO:0008484:sulfuric ester hydrolase activity;	K01134	;ko00600 Sphingolipid metabolism;ko04142 Lysosome;
ENSMUSG00000058099	7970	138	0.90	131	0.94	35	0.20	30	0.22	81.6597059931602	0.251410052056517	-1.99188576111077	0.34781191390259	-5.72690492042384	1.022794530601e-08	4.82570194838024e-07	Down	15	82877174	82917507	-	Nfam1	Nfat activating molecule with ITAM motif 1 [Source:MGI Symbol%3BAcc:MGI:1921289]	GO:0030183:B cell differentiation;GO:0050853:B cell receptor signaling pathway;GO:0035556:intracellular signal transduction;GO:0050861:positive regulation of B cell receptor signaling pathway;GO:0001819:positive regulation of cytokine production;GO:0051091:positive regulation of sequence-specific DNA binding transcription factor activity;GO:0045577:regulation of B cell differentiation;GO:0007165:signal transduction;	GO:0009986:cell surface;GO:0016021:integral component of membrane;GO:0045121:membrane raft;GO:0005886:plasma membrane;	GO:0004888:transmembrane signaling receptor activity;	-	-
ENSMUSG00000029304	1648	407	12.82	253	8.74	123	3.43	92	3.32	213.082119221129	0.3391808424087	-1.55987340889689	0.272780515345983	-5.71841946598869	1.07519454182709e-08	5.05737211790692e-07	Down	5	104582984	104588916	+	Spp1	secreted phosphoprotein 1 [Source:MGI Symbol%3BAcc:MGI:98389]	GO:0006710:androgen catabolic process;GO:0031214:biomineral tissue development;GO:0007155:cell adhesion;GO:0006874:cellular calcium ion homeostasis;GO:0030644:cellular chloride ion homeostasis;GO:0030643:cellular phosphate ion homeostasis;GO:0071498:cellular response to fluid shear stress;GO:0071394:cellular response to testosterone stimulus;GO:0006883:cellular sodium ion homeostasis;GO:0072044:collecting duct development;GO:0043066:negative regulation of apoptotic process;GO:0030593:neutrophil chemotaxis;GO:0001649:osteoblast differentiation;GO:0045780:positive regulation of bone resorption;GO:0010811:positive regulation of cell-substrate adhesion;GO:2000866:positive regulation of estradiol secretion;GO:0045893:positive regulation of transcription, DNA-templated;GO:0010033:response to organic substance;GO:0048545:response to steroid hormone;GO:0033280:response to vitamin D;GO:0034418:urate biosynthetic process;	GO:0045177:apical part of cell;GO:0042995:cell projection;GO:0005737:cytoplasm;GO:0005576:extracellular region;GO:0005615:extracellular space;GO:0005794:Golgi apparatus;GO:0048471:perinuclear region of cytoplasm;GO:0031982:vesicle;	GO:0005125:cytokine activity;GO:0050840:extracellular matrix binding;GO:0005178:integrin binding;	K06250	;ko04151 PI3K-Akt signaling pathway;ko04371 Apelin signaling pathway;ko04510 Focal adhesion;ko04512 ECM-receptor interaction;ko04620 Toll-like receptor signaling pathway;ko04929 GnRH secretion;ko05165 Human papillomavirus infection;
ENSMUSG00000040666	1570	88	2.91	62	2.25	5	0.15	9	0.34	39.8903130833861	0.0987377279623761	-3.34025474193215	0.584966754452307	-5.71016167416141	1.12868900648391e-08	5.29275756129183e-07	Down	16	96001650	96030135	+	Sh3bgr	SH3-binding domain glutamic acid-rich protein [Source:MGI Symbol%3BAcc:MGI:1354740]	GO:0065003:macromolecular complex assembly;	GO:0005829:cytosol;	GO:0017124:SH3 domain binding;	-	-
ENSMUSG00000084883	4337	63	0.75	43	0.56	230	2.44	140	1.92	117.523066419115	3.59355466219442	1.84541163131512	0.323667866134147	5.70155960601377	1.18716208886383e-08	5.54998276543838e-07	Ups	12	108169861	108241684	-	Ccdc85c	coiled-coil domain containing 85C [Source:MGI Symbol%3BAcc:MGI:3644008]	GO:0021987:cerebral cortex development;	GO:0005912:adherens junction;GO:0043296:apical junction complex;GO:0005923:bicellular tight junction;	-	-	-
ENSMUSG00000051285	6654	1540	12.02	1701	14.55	581	4.02	741	6.63	1128.09335424604	0.431462419823022	-1.21269318808109	0.213004546834679	-5.69327371693297	1.24626351396419e-08	5.80857286417229e-07	Down	1	7159144	7243852	+	Pcmtd1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 [Source:MGI Symbol%3BAcc:MGI:2441773]	-	GO:0005737:cytoplasm;GO:0016020:membrane;	GO:0004719:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity;	-	-
ENSMUSG00000017631	10974	605	2.86	538	2.79	301	1.26	239	1.30	412.847231205981	0.490747590811969	-1.0269469096863	0.180421072026693	-5.69194550365136	1.25599945455851e-08	5.83621079884855e-07	Down	11	76307560	76514384	-	Abr	active BCR-related gene [Source:MGI Symbol%3BAcc:MGI:107771]	GO:0030036:actin cytoskeleton organization;GO:0090630:activation of GTPase activity;GO:0007420:brain development;GO:0042472:inner ear morphogenesis;GO:0035556:intracellular signal transduction;GO:0050804:regulation of synaptic transmission;GO:0060313:negative regulation of blood vessel remodeling;GO:0030336:negative regulation of cell migration;GO:0002692:negative regulation of cellular extravasation;GO:0050728:negative regulation of inflammatory response;GO:0043314:negative regulation of neutrophil degranulation;GO:0050885:neuromuscular process controlling balance;GO:0050766:positive regulation of phagocytosis;GO:0043114:regulation of vascular permeability;GO:0032496:response to lipopolysaccharide;	GO:0030424:axon;GO:0005829:cytosol;GO:0043197:dendritic spine;GO:0016020:membrane;GO:0005886:plasma membrane;	GO:0005096:GTPase activator activity;GO:0005085:guanyl-nucleotide exchange factor activity;	K08878	;ko05200 Pathways in cancer;ko05220 Chronic myeloid leukemia;
ENSMUSG00000074604	3703	152	2.13	156	2.40	34	0.42	42	0.68	94.3206615978941	0.259270791872053	-1.94746840622336	0.342445020710823	-5.68695203154347	1.2932676324967e-08	5.98249397610867e-07	Down	3	51567781	51590098	+	Mgst2	microsomal glutathione S-transferase 2 [Source:MGI Symbol%3BAcc:MGI:2448481]	GO:0006750:glutathione biosynthetic process;GO:0019370:leukotriene biosynthetic process;GO:0006629:lipid metabolic process;GO:0046466:membrane lipid catabolic process;	GO:0005737:cytoplasm;GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0016021:integral component of membrane;GO:0043231:intracellular membrane-bounded organelle;GO:0016020:membrane;GO:0005635:nuclear envelope;GO:0005886:plasma membrane;	GO:0008047:enzyme activator activity;GO:0043295:glutathione binding;GO:0004602:glutathione peroxidase activity;GO:0004364:glutathione transferase activity;GO:0042802:identical protein binding;GO:0004464:leukotriene-C4 synthase activity;	K00799	;ko00480 Glutathione metabolism;ko00980 Metabolism of xenobiotics by cytochrome P450;ko00982 Drug metabolism - cytochrome P450;ko00983 Drug metabolism - other enzymes;ko01100 Metabolic pathways;ko01524 Platinum drug resistance;ko04212 Longevity regulating pathway - worm;ko05200 Pathways in cancer;ko05204 Chemical carcinogenesis;ko05225 Hepatocellular carcinoma;ko05418 Fluid shear stress and atherosclerosis;
ENSMUSG00000028634	17627	3855	11.35	3209	10.36	1492	3.89	1723	5.82	2533.91143156249	0.48140812732015	-1.05466759672784	0.185720160258822	-5.67879973427787	1.3564317678233e-08	6.24610352186262e-07	Down	4	119590981	119995242	+	Hivep3	human immunodeficiency virus type I enhancer binding protein 3 [Source:MGI Symbol%3BAcc:MGI:106589]	GO:0045893:positive regulation of transcription, DNA-templated;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0035914:skeletal muscle cell differentiation;	GO:0005829:cytosol;GO:0005634:nucleus;	GO:0003677:DNA binding;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046872:metal ion binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K09239	-
ENSMUSG00000019960	3132	552	9.15	574	10.43	301	4.42	219	4.16	403.74935414075	0.477185091166669	-1.0673791256931	0.18807469501764	-5.67529366772595	1.3845093236515e-08	6.33733312503643e-07	Down	10	99099093	99103351	+	Dusp6	dual specificity phosphatase 6 [Source:MGI Symbol%3BAcc:MGI:1914853]	GO:0030154:cell differentiation;GO:0000188:inactivation of MAPK activity;GO:0070373:negative regulation of ERK1 and ERK2 cascade;GO:0001933:negative regulation of protein phosphorylation;GO:0035970:peptidyl-threonine dephosphorylation;GO:0035335:peptidyl-tyrosine dephosphorylation;GO:0043065:positive regulation of apoptotic process;GO:0010942:positive regulation of cell death;GO:0006470:protein dephosphorylation;GO:0060420:regulation of heart growth;GO:0042493:response to drug;GO:0070848:response to growth factor;GO:0051409:response to nitrosative stress;GO:0014070:response to organic cyclic compound;GO:0010033:response to organic substance;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005654:nucleoplasm;	GO:0017017:MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0051019:mitogen-activated protein kinase binding;GO:0004721:phosphoprotein phosphatase activity;GO:0004725:protein tyrosine phosphatase activity;GO:0008138:protein tyrosine/serine/threonine phosphatase activity;GO:0008330:protein tyrosine/threonine phosphatase activity;	K04459	;ko04010 MAPK signaling pathway;ko04361 Axon regeneration;
ENSMUSG00000038059	6828	328	2.49	266	2.22	715	4.82	502	4.38	448.177864151764	2.11857710687924	1.08309563740509	0.191151417713234	5.66616586140082	1.46028178463436e-08	6.66427407309028e-07	Ups	18	60607263	60635059	-	Smim3	small integral membrane protein 3 [Source:MGI Symbol%3BAcc:MGI:1917088]	-	GO:0016021:integral component of membrane;	GO:0042802:identical protein binding;	-	-
ENSMUSG00000027071	2789	80	1.49	96	1.96	11	0.18	14	0.30	49.2635075922475	0.148646140208165	-2.75004609262287	0.485520035312708	-5.66412484059828	1.47776793116316e-08	6.72406334019461e-07	Down	2	84828927	84867806	-	P2rx3	purinergic receptor P2X%2C ligand-gated ion channel%2C 3 [Source:MGI Symbol%3BAcc:MGI:1097160]	GO:0061368:behavioral response to formalin induced pain;GO:0048266:behavioral response to pain;GO:0006812:cation transport;GO:0071318:cellular response to ATP;GO:0007268:synaptic transmission;GO:0098662:inorganic cation transmembrane transport;GO:0006811:ion transport;GO:0050804:regulation of synaptic transmission;GO:0007274:neuromuscular synaptic transmission;GO:0019228:neuronal action potential;GO:0030432:peristalsis;GO:1904058:positive regulation of sensory perception of pain;GO:0070207:protein homotrimerization;GO:0048167:regulation of synaptic plasticity;GO:0033198:response to ATP;GO:0009743:response to carbohydrate;GO:0009409:response to cold;GO:0009408:response to heat;GO:0001666:response to hypoxia;GO:0009612:response to mechanical stimulus;GO:0010033:response to organic substance;GO:0009266:response to temperature stimulus;GO:0050909:sensory perception of taste;GO:0014832:urinary bladder smooth muscle contraction;	GO:0030424:axon;GO:0043197:dendritic spine;GO:0005794:Golgi apparatus;GO:0005639:integral component of nuclear inner membrane;GO:0005887:integral component of plasma membrane;GO:0016020:membrane;GO:0045121:membrane raft;GO:0043005:neuron projection;GO:0043025:neuronal cell body;GO:0043235:receptor complex;GO:0005791:rough endoplasmic reticulum;GO:0043195:terminal bouton;	GO:0005524:ATP binding;GO:0004931:extracellular ATP-gated cation channel activity;GO:0042802:identical protein binding;GO:0001614:purinergic nucleotide receptor activity;	K05217	;ko04020 Calcium signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04742 Taste transduction;
ENSMUSG00000114552	393	2	0.26	8	1.16	49	5.74	100	15.15	41.6401818586649	15.9782222912983	3.99803500038765	0.709243591066434	5.63704071597759	1.72997221103412e-08	7.71145171046431e-07	Ups	13	41555767	41556829	+	Gm48570	predicted gene%2C 48570 [Source:MGI Symbol%3BAcc:MGI:6098132]	-	-	-	-	-
ENSMUSG00000021613	5902	92	0.81	109	1.05	22	0.17	14	0.14	57.8662335973417	0.184507357922993	-2.43824974457812	0.433277268417879	-5.62745826357667	1.82884393811038e-08	8.1285486802854e-07	Down	13	89687915	89759771	+	Hapln1	hyaluronan and proteoglycan link protein 1 [Source:MGI Symbol%3BAcc:MGI:1337006]	GO:0007155:cell adhesion;GO:0007417:central nervous system development;GO:0001501:skeletal system development;	GO:0031012:extracellular matrix;GO:0005576:extracellular region;GO:0045202:synapse;	GO:0005540:hyaluronic acid binding;	K06848	-
ENSMUSG00000090733	1043	4068	202.48	4118	224.68	10588	467.12	6104	348.54	6124.16720571099	2.08205140428232	1.0580056881319	0.188061305243079	5.62585528567066	1.84591052441636e-08	8.18069132410418e-07	Ups	3	90119829	90120958	-	Rps27	ribosomal protein S27 [Source:MGI Symbol%3BAcc:MGI:1888676]	GO:0006412:translation;	GO:0005840:ribosome;	GO:0046872:metal ion binding;GO:0003735:structural constituent of ribosome;	K02978	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000022667	3348	103	1.60	115	1.95	18	0.25	23	0.41	63.5508792700728	0.197294111470252	-2.34158019751541	0.416939070598941	-5.61612082588395	1.95292123972498e-08	8.6299983544504e-07	Down	16	44586099	44615341	+	Cd200r1	CD200 receptor 1 [Source:MGI Symbol%3BAcc:MGI:1889024]	GO:0034113:heterotypic cell-cell adhesion;GO:0032715:negative regulation of interleukin-6 production;GO:1901215:negative regulation of neuron death;GO:2000405:negative regulation of T cell migration;	GO:0009986:cell surface;GO:0009897:external side of plasma membrane;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;GO:0043235:receptor complex;	GO:0086080:protein binding involved in heterotypic cell-cell adhesion;GO:0038023:signaling receptor activity;	-	-
ENSMUSG00000018398	6087	6	0.05	16	0.15	96	0.73	70	0.68	47.0080662984526	7.75231322565415	2.95462686280262	0.526798798838154	5.60864388703808	2.03918124378547e-08	8.98528884833517e-07	Ups	11	53410084	53440392	+	Septin8	septin 8 [Source:MGI Symbol%3BAcc:MGI:894310]	GO:0034613:cellular protein localization;GO:0061640:cytoskeleton-dependent cytokinesis;GO:0033157:regulation of intracellular protein transport;GO:0031647:regulation of protein stability;GO:0035542:regulation of SNARE complex assembly;	GO:0030424:axon;GO:0032153:cell division site;GO:0015630:microtubule cytoskeleton;GO:0043209:myelin sheath;GO:0098793:presynapse;GO:0031105:septin complex;GO:0005940:septin ring;GO:0030672:synaptic vesicle membrane;	GO:0005525:GTP binding;GO:0003924:GTPase activity;GO:0060090:binding, bridging;GO:0000149:SNARE binding;	K16939	;ko05100 Bacterial invasion of epithelial cells;ko05131 Shigellosis;
ENSMUSG00000029299	3550	293	4.28	270	4.33	88	1.14	105	1.76	186.022202314491	0.361043733084983	-1.46975449410891	0.262821371773672	-5.59221833517628	2.24186655001618e-08	9.79395489400232e-07	Down	5	105082923	105130584	-	Abcg3	ATP binding cassette subfamily G member 3 [Source:MGI Symbol%3BAcc:MGI:1351624]	-	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0005524:ATP binding;GO:0042626:ATPase activity, coupled to transmembrane movement of substances;	K05682	;ko02010 ABC transporters;
ENSMUSG00000037907	3839	120	1.62	103	1.53	366	4.39	222	3.44	200.083071283903	2.70839434863619	1.43743781402421	0.25739931110168	5.58446643804878	2.34418779949433e-08	1.01829392967269e-06	Ups	11	77361311	77380504	-	Ankrd13b	ankyrin repeat domain 13b [Source:MGI Symbol%3BAcc:MGI:2144501]	GO:0002091:negative regulation of receptor internalization;	GO:0005737:cytoplasm;GO:0005769:early endosome;GO:0043231:intracellular membrane-bounded organelle;GO:0005770:late endosome;GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;	-	-	-
ENSMUSG00000086205	636	14	1.14	24	2.15	94	6.80	111	10.39	61.8754596577991	5.66708792990662	2.50260758731705	0.448813986054355	5.57604634676861	2.4604639988381e-08	1.06578403836676e-06	Ups	4	44970576	44978319	-	Gm12679	predicted gene 12679 [Source:MGI Symbol%3BAcc:MGI:3650924]	-	-	-	-	-
ENSMUSG00000022701	4230	299	3.67	333	4.48	136	1.48	113	1.59	216.424574386624	0.408809591190193	-1.29049905076396	0.231919207898736	-5.56443367695286	2.63005131600657e-08	1.13284288987766e-06	Down	16	43710163	43784677	+	Ccdc191	coiled-coil domain containing 191 [Source:MGI Symbol%3BAcc:MGI:1922661]	-	-	-	-	-
ENSMUSG00000024462	7764	313	2.09	435	3.19	135	0.80	131	1.00	249.977650830551	0.370105660410979	-1.43399089444404	0.258164086980204	-5.55457155647678	2.78293495816342e-08	1.19199789520888e-06	Down	17	37356858	37385959	+	Gabbr1	gamma-aminobutyric acid (GABA) B receptor%2C 1 [Source:MGI Symbol%3BAcc:MGI:1860139]	GO:0007193:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007214:gamma-aminobutyric acid signaling pathway;GO:0007194:negative regulation of adenylate cyclase activity;GO:0008285:negative regulation of cell proliferation;GO:0033602:negative regulation of dopamine secretion;GO:0032811:negative regulation of epinephrine secretion;GO:0014053:negative regulation of gamma-aminobutyric acid secretion;GO:0050805:negative regulation of synaptic transmission;GO:0001649:osteoblast differentiation;GO:0014049:positive regulation of glutamate secretion;GO:0060124:positive regulation of growth hormone secretion;GO:0014048:regulation of glutamate secretion;	GO:0030673:axolemma;GO:0005737:cytoplasm;GO:0043198:dendritic shaft;GO:0043197:dendritic spine;GO:0005789:endoplasmic reticulum membrane;GO:0005615:extracellular space;GO:0038037:G-protein coupled receptor dimeric complex;GO:0038039:G-protein coupled receptor heterodimeric complex;GO:1902710:GABA receptor complex;GO:0005887:integral component of plasma membrane;GO:0043231:intracellular membrane-bounded organelle;GO:0016020:membrane;GO:0045121:membrane raft;GO:0031966:mitochondrial membrane;GO:0043005:neuron projection;GO:0043025:neuronal cell body;GO:0045211:postsynaptic membrane;GO:0098793:presynapse;GO:0042734:presynaptic membrane;GO:0097060:synaptic membrane;GO:0008021:synaptic vesicle;GO:0030425:dendrite;GO:0005576:extracellular region;GO:0005886:plasma membrane;	GO:1990430:extracellular matrix protein binding;GO:0004965:G-protein coupled GABA receptor activity;GO:0046982:protein heterodimerization activity;GO:0004888:transmembrane signaling receptor activity;	K04615	;ko04024 cAMP signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04727 GABAergic synapse;ko04742 Taste transduction;ko04915 Estrogen signaling pathway;ko04929 GnRH secretion;ko05032 Morphine addiction;
ENSMUSG00000001751	2658	343	6.70	385	8.24	171	2.96	128	2.87	252.010402121651	0.424538878396999	-1.23603141601557	0.222676564581886	-5.55079255123425	2.84377383209745e-08	1.21466373095772e-06	Down	11	100960838	100968498	+	Naglu	alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) [Source:MGI Symbol%3BAcc:MGI:1351641]	GO:0021680:cerebellar Purkinje cell layer development;GO:0006027:glycosaminoglycan catabolic process;GO:0060119:inner ear receptor cell development;GO:0045475:locomotor rhythm;GO:0007040:lysosome organization;GO:0042474:middle ear morphogenesis;GO:0007399:nervous system development;GO:0046548:retinal rod cell development;	GO:0070062:extracellular exosome;GO:0043202:lysosomal lumen;GO:0005764:lysosome;	GO:0004561:alpha-N-acetylglucosaminidase activity;	K01205	;ko00531 Glycosaminoglycan degradation;ko01100 Metabolic pathways;ko04142 Lysosome;
ENSMUSG00000000247	4393	8	0.09	12	0.16	85	0.89	61	0.83	41.4415456196343	7.52421058868121	2.91154022778115	0.524941263946263	5.54641143257352	2.91592224408125e-08	1.24202088029839e-06	Ups	2	38229293	38259745	+	Lhx2	LIM homeobox protein 2 [Source:MGI Symbol%3BAcc:MGI:96785]	GO:0048646:anatomical structure formation involved in morphogenesis;GO:0048675:axon extension;GO:0007411:axon guidance;GO:0007420:brain development;GO:0021987:cerebral cortex development;GO:0009953:dorsal/ventral pattern formation;GO:0001942:hair follicle development;GO:0045199:maintenance of epithelial cell apical/basal polarity;GO:0007498:mesoderm development;GO:0045814:negative regulation of gene expression, epigenetic;GO:0050768:negative regulation of neurogenesis;GO:2000678:negative regulation of transcription regulatory region DNA binding;GO:0007399:nervous system development;GO:0001843:neural tube closure;GO:0022008:neurogenesis;GO:0030182:neuron differentiation;GO:0021772:olfactory bulb development;GO:2000179:positive regulation of neural precursor cell proliferation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-templated;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0060041:retina development in camera-type eye;GO:0021537:telencephalon development;GO:0021978:telencephalon regionalization;	GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0000785:chromatin;	GO:0003682:chromatin binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046872:metal ion binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000977:RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565:sequence-specific DNA binding;	K09373	-
ENSMUSG00000072294	6985	290	2.16	332	2.70	113	0.74	117	1.00	209.883050033483	0.386546937553395	-1.3712844867812	0.247477652007795	-5.5410437090215	3.00674149661238e-08	1.27715717753613e-06	Down	14	100108068	100522115	-	Klf12	Kruppel-like factor 12 [Source:MGI Symbol%3BAcc:MGI:1333796]	GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0006355:regulation of transcription, DNA-templated;	GO:0005829:cytosol;GO:0005654:nucleoplasm;GO:0000785:chromatin;	GO:0003677:DNA binding;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001227:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0046872:metal ion binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000977:RNA polymerase II regulatory region sequence-specific DNA binding;	K09205	-
ENSMUSG00000024887	11638	228	1.02	203	0.99	66	0.26	73	0.37	139.98237849976	0.338666642127888	-1.56206220314447	0.282101850892658	-5.53722777146486	3.07296804499353e-08	1.30130202818557e-06	Down	19	31959997	32085611	-	Asah2	N-acylsphingosine amidohydrolase 2 [Source:MGI Symbol%3BAcc:MGI:1859310]	GO:0006915:apoptotic process;GO:0071345:cellular response to cytokine stimulus;GO:0046513:ceramide biosynthetic process;GO:0046514:ceramide catabolic process;GO:0006672:ceramide metabolic process;GO:0044241:lipid digestion;GO:0042759:long-chain fatty acid biosynthetic process;GO:2001234:negative regulation of apoptotic signaling pathway;GO:0007346:regulation of mitotic cell cycle;GO:0010033:response to organic substance;GO:0046512:sphingosine biosynthetic process;GO:0006670:sphingosine metabolic process;	GO:0005901:caveola;GO:0070062:extracellular exosome;GO:0005576:extracellular region;GO:0005615:extracellular space;GO:0005794:Golgi apparatus;GO:0000139:Golgi membrane;GO:0005887:integral component of plasma membrane;GO:0016020:membrane;GO:0005739:mitochondrion;GO:0005886:plasma membrane;	GO:0005509:calcium ion binding;GO:0071633:dihydroceramidase activity;GO:0017040:ceramidase activity;GO:0070774:phytoceramidase activity;GO:0008270:zinc ion binding;	K12349	;ko00600 Sphingolipid metabolism;ko01100 Metabolic pathways;ko04071 Sphingolipid signaling pathway;
ENSMUSG00000071714	4740	900	9.86	642	7.71	1504	14.60	1682	21.13	1187.60159042642	2.1866098697662	1.12869584079713	0.203853622761551	5.53679559630576	3.08055716858851e-08	1.30130202818557e-06	Ups	15	78166707	78189921	-	Csf2rb2	colony stimulating factor 2 receptor%2C beta 2%2C low-affinity (granulocyte-macrophage) [Source:MGI Symbol%3BAcc:MGI:1339760]	-	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0004896:cytokine receptor activity;	K04738	;ko04060 Cytokine-cytokine receptor interaction;ko04210 Apoptosis;ko04630 JAK-STAT signaling pathway;ko05200 Pathways in cancer;
ENSMUSG00000014932	7508	46	0.32	73	0.55	205	1.26	182	1.44	126.978162398507	3.37421027124779	1.75454988110445	0.316965702080795	5.53545657964349	3.10418631779478e-08	1.307681126293e-06	Ups	5	32768515	32844401	+	Yes1	YES proto-oncogene 1%2C Src family tyrosine kinase [Source:MGI Symbol%3BAcc:MGI:99147]	GO:0030154:cell differentiation;GO:0036120:cellular response to platelet-derived growth factor stimulus;GO:0071300:cellular response to retinoic acid;GO:0071560:cellular response to transforming growth factor beta stimulus;GO:0045087:innate immune response;GO:0050731:positive regulation of peptidyl-tyrosine phosphorylation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0046777:protein autophosphorylation;GO:0010827:regulation of glucose transport;GO:0007169:transmembrane receptor protein tyrosine kinase signaling pathway;	GO:0005884:actin filament;GO:0005829:cytosol;GO:0031234:extrinsic component of cytoplasmic side of plasma membrane;GO:0005794:Golgi apparatus;GO:0005815:microtubule organizing center;GO:0005886:plasma membrane;	GO:0005524:ATP binding;GO:0019899:enzyme binding;GO:0005154:epidermal growth factor receptor binding;GO:0004715:non-membrane spanning protein tyrosine kinase activity;GO:0001784:phosphotyrosine binding;GO:0004713:protein tyrosine kinase activity;GO:0005102:receptor binding;GO:0004714:transmembrane receptor protein tyrosine kinase activity;GO:0044325:ion channel binding;	K05705;K09228	;ko04520 Adherens junction;;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000031910	6380	51	0.41	42	0.37	152	1.10	153	1.43	100.146315046096	3.44110040956236	1.7828699897977	0.322456009840748	5.52903321813791	3.22000374599026e-08	1.35275445043876e-06	Ups	8	107596874	107611198	+	Has3	hyaluronan synthase 3 [Source:MGI Symbol%3BAcc:MGI:109599]	GO:0085029:extracellular matrix assembly;GO:0045226:extracellular polysaccharide biosynthetic process;GO:0030213:hyaluronan biosynthetic process;GO:1900106:positive regulation of hyaluranon cable assembly;GO:0045893:positive regulation of transcription, DNA-templated;	GO:0005737:cytoplasm;GO:0036117:hyaluranon cable;GO:0005887:integral component of plasma membrane;GO:0005634:nucleus;	GO:0050501:hyaluronan synthase activity;GO:0042802:identical protein binding;	K00752	-
ENSMUSG00000042082	6037	593	5.10	525	4.95	308	2.35	217	2.14	402.24068310376	0.485603603326951	-1.04214896801651	0.188962069186641	-5.51512254550497	3.48537013483906e-08	1.45230069694625e-06	Down	13	93908138	94079524	+	Arsb	arylsulfatase B [Source:MGI Symbol%3BAcc:MGI:88075]	GO:0097065:anterior head development;GO:0006914:autophagy;GO:0007417:central nervous system development;GO:0061580:colon epithelial cell migration;GO:0010976:positive regulation of neuron projection development;GO:0010632:regulation of epithelial cell migration;GO:0043627:response to estrogen;GO:0051597:response to methylmercury;GO:0007584:response to nutrient;GO:0009268:response to pH;	GO:0009986:cell surface;GO:0005794:Golgi apparatus;GO:0005764:lysosome;GO:0005739:mitochondrion;GO:0005791:rough endoplasmic reticulum;	GO:0004065:arylsulfatase activity;GO:0046872:metal ion binding;GO:0003943:N-acetylgalactosamine-4-sulfatase activity;GO:0008484:sulfuric ester hydrolase activity;	K01135	;ko00531 Glycosaminoglycan degradation;ko01100 Metabolic pathways;ko04142 Lysosome;
ENSMUSG00000008305	8711	136	0.81	132	0.86	330	1.74	274	1.87	217.335064654304	2.34265397766838	1.22814387628059	0.222715168247534	5.51441505284269	3.49941875988829e-08	1.45420290688691e-06	Ups	4	72035379	72119156	-	Tle1	transducin-like enhancer of split 1 [Source:MGI Symbol%3BAcc:MGI:104636]	GO:2000811:negative regulation of anoikis;GO:0090090:negative regulation of canonical Wnt signaling pathway;GO:0043124:negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0045892:negative regulation of transcription, DNA-templated;GO:0010628:positive regulation of gene expression;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0006355:regulation of transcription, DNA-templated;GO:0016055:Wnt signaling pathway;GO:0009887:organ morphogenesis;GO:0007275:multicellular organismal development;GO:0030178:negative regulation of Wnt signaling pathway;GO:0007165:signal transduction;	GO:0005829:cytosol;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0005667:transcription factor complex;	GO:0003682:chromatin binding;GO:0042802:identical protein binding;GO:0003714:transcription corepressor activity;GO:0008134:transcription factor binding;	-	-
ENSMUSG00000061981	2740	426	8.07	403	8.37	213	3.58	155	3.37	293.267053753114	0.459345181986017	-1.12234939837126	0.203629639344564	-5.51171922704299	3.55345463738046e-08	1.47266684890789e-06	Down	11	77928757	77951260	+	Flot2	flotillin 2 [Source:MGI Symbol%3BAcc:MGI:103309]	GO:0007155:cell adhesion;GO:0001765:membrane raft assembly;GO:1902992:negative regulation of amyloid precursor protein catabolic process;GO:0010629:negative regulation of gene expression;GO:1903905:positive regulation of establishment of T cell polarity;GO:0051092:positive regulation of NF-kappaB transcription factor activity;GO:0072659:protein localization to plasma membrane;GO:0044860:protein localization to plasma membrane raft;GO:0050821:protein stabilization;GO:0045661:regulation of myoblast differentiation;	GO:0002080:acrosomal membrane;GO:0005912:adherens junction;GO:0016323:basolateral plasma membrane;GO:0005901:caveola;GO:0044291:cell-cell contact zone;GO:0030864:cortical actin cytoskeleton;GO:0031410:cytoplasmic vesicle;GO:0032839:dendrite cytoplasm;GO:0030139:endocytic vesicle;GO:0005768:endosome;GO:0016600:flotillin complex;GO:0043231:intracellular membrane-bounded organelle;GO:0030027:lamellipodium;GO:0016020:membrane;GO:0045121:membrane raft;GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;GO:0045202:synapse;GO:0001931:uropod;GO:0031982:vesicle;	GO:0035255:ionotropic glutamate receptor binding;GO:0002020:protease binding;	K07192	;ko04910 Insulin signaling pathway;
ENSMUSG00000108732	3881	299	4.00	277	4.06	112	1.33	110	1.69	196.095426256389	0.403100444848685	-1.31078871958565	0.238614007050741	-5.49334356263049	3.94394473033349e-08	1.61270529319823e-06	Down	7	34089157	34093037	+	2310043P16Rik	RIKEN cDNA 2310043P16 gene [Source:MGI Symbol%3BAcc:MGI:1917385]	-	-	-	-	-
ENSMUSG00000047747	17242	130	0.39	109	0.36	21	0.06	29	0.10	70.7856676403577	0.220857470482009	-2.17881246266746	0.397798070731342	-5.47718207547303	4.32152489914615e-08	1.74384902114492e-06	Down	8	83589985	83817897	+	Rnf150	ring finger protein 150 [Source:MGI Symbol%3BAcc:MGI:2443860]	GO:0006511:ubiquitin-dependent protein catabolic process;	GO:0005737:cytoplasm;GO:0016021:integral component of membrane;	GO:0046872:metal ion binding;GO:0061630:ubiquitin protein ligase activity;	K15701	-
ENSMUSG00000000782	3019	203	3.49	153	2.88	435	6.63	341	6.73	281.209300676367	2.26640112388091	1.18040322224385	0.215874821661814	5.46799859824806	4.55145481177754e-08	1.83181123579519e-06	Ups	11	52143198	52174158	-	Tcf7	transcription factor 7%2C T cell specific [Source:MGI Symbol%3BAcc:MGI:98507]	GO:0046632:alpha-beta T cell differentiation;GO:0060070:canonical Wnt signaling pathway;GO:0044336:canonical Wnt signaling pathway involved in negative regulation of apoptotic process;GO:0048557:embryonic digestive tract morphogenesis;GO:0030538:embryonic genitalia morphogenesis;GO:0048619:embryonic hindgut morphogenesis;GO:0042492:gamma-delta T cell differentiation;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0021915:neural tube development;GO:0042127:regulation of cell proliferation;GO:0045586:regulation of gamma-delta T cell differentiation;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0006355:regulation of transcription, DNA-templated;GO:0033153:T cell receptor V(D)J recombination;	GO:0000791:euchromatin;GO:0005634:nucleus;	GO:0008013:beta-catenin binding;GO:0003677:DNA binding;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001217:sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription;GO:0001227:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K02620	;ko04310 Wnt signaling pathway;ko04390 Hippo signaling pathway;ko04520 Adherens junction;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04916 Melanogenesis;ko04934 Cushing syndrome;ko05132 Salmonella infection;ko05165 Human papillomavirus infection;ko05167 Kaposi sarcoma-associated herpesvirus infection;ko05200 Pathways in cancer;ko05210 Colorectal cancer;ko05213 Endometrial cancer;ko05215 Prostate cancer;ko05216 Thyroid cancer;ko05217 Basal cell carcinoma;ko05221 Acute myeloid leukemia;ko05224 Breast cancer;ko05225 Hepatocellular carcinoma;ko05226 Gastric cancer;ko05412 Arrhythmogenic right ventricular cardiomyopathy;
ENSMUSG00000015027	2650	635	12.44	530	11.38	313	5.44	176	3.96	403.100106741296	0.430453043517885	-1.21607222678606	0.222853471896028	-5.45682423719841	4.84725735165694e-08	1.93562094349759e-06	Down	8	123304981	123338202	-	Galns	galactosamine (N-acetyl)-6-sulfate sulfatase [Source:MGI Symbol%3BAcc:MGI:1355303]	-	GO:0005764:lysosome;	GO:0004065:arylsulfatase activity;GO:0046872:metal ion binding;GO:0043890:N-acetylgalactosamine-6-sulfatase activity;GO:0008484:sulfuric ester hydrolase activity;	K01132	;ko00531 Glycosaminoglycan degradation;ko01100 Metabolic pathways;ko04142 Lysosome;
ENSMUSG00000035246	5357	76	0.74	87	0.92	16	0.14	8	0.09	45.5482763326911	0.151068962517373	-2.72672080911518	0.500005816507797	-5.45337817899696	4.9421807329183e-08	1.96330050151734e-06	Down	X	92698469	92793557	+	Pcyt1b	phosphate cytidylyltransferase 1%2C choline%2C beta isoform [Source:MGI Symbol%3BAcc:MGI:2147987]	GO:0006657:CDP-choline pathway;GO:0001541:ovarian follicle development;GO:0006656:phosphatidylcholine biosynthetic process;GO:0007283:spermatogenesis;GO:1904116:response to vasopressin;	GO:0005783:endoplasmic reticulum;	GO:0004105:choline-phosphate cytidylyltransferase activity;GO:0042802:identical protein binding;GO:0031210:phosphatidylcholine binding;	K00968	;ko00440 Phosphonate and phosphinate metabolism;ko00564 Glycerophospholipid metabolism;ko01100 Metabolic pathways;ko05231 Choline metabolism in cancer;
ENSMUSG00000043279	9281	2489	13.92	2083	12.77	985	4.88	1141	7.32	1651.74894132212	0.491746547592104	-1.02401317108561	0.188404299883066	-5.43519002337617	5.473806622565e-08	2.16887211241374e-06	Down	5	137134498	137145063	-	Trim56	tripartite motif-containing 56 [Source:MGI Symbol%3BAcc:MGI:2685298]	GO:0051607:defense response to virus;GO:0045087:innate immune response;GO:0046597:negative regulation of viral entry into host cell;GO:1902187:negative regulation of viral release from host cell;GO:0032728:positive regulation of interferon-beta production;GO:0045893:positive regulation of transcription, DNA-templated;GO:0070534:protein K63-linked ubiquitination;GO:0034340:response to type I interferon;	GO:0000785:chromatin;GO:0005737:cytoplasm;GO:0005654:nucleoplasm;	GO:0061630:ubiquitin protein ligase activity;GO:0004842:ubiquitin-protein transferase activity;GO:0008270:zinc ion binding;	K12026	-
ENSMUSG00000037355	8666	864	5.18	813	5.34	328	1.74	399	2.74	593.43073073302	0.458094544367487	-1.12628271356569	0.208043091306928	-5.41369918361805	6.17358485932645e-08	2.42111893178802e-06	Down	5	33535893	33577098	+	Uvssa	UV stimulated scaffold protein A [Source:MGI Symbol%3BAcc:MGI:1918351]	GO:0016567:protein ubiquitination;GO:0009411:response to UV;GO:0006283:transcription-coupled nucleotide-excision repair;	GO:0005694:chromosome;GO:0005654:nucleoplasm;	GO:0000993:RNA polymerase II core binding;	-	-
ENSMUSG00000117219	287	108	19.54	163	32.32	12	1.92	30	6.23	77.2847839504068	0.165407913964538	-2.59589983278293	0.479551807474706	-5.41317912334185	6.19154971555611e-08	2.42196998312085e-06	Down	17	24032188	24032474	-	Gm49911	predicted gene%2C 49911 [Source:MGI Symbol%3BAcc:MGI:6270612]	-	-	-	-	-
ENSMUSG00000064065	9003	387	2.23	332	2.10	140	0.72	149	0.99	247.897690385011	0.422194039031985	-1.24402188550524	0.229905550075676	-5.41101284895365	6.26692747482749e-08	2.44521796180674e-06	Down	10	6835796	7002478	-	Ipcef1	interaction protein for cytohesin exchange factors 1 [Source:MGI Symbol%3BAcc:MGI:2444159]	GO:2001114:positive regulation of cellular response to hepatocyte growth factor stimulus;GO:0009966:regulation of signal transduction;	GO:0005829:cytosol;GO:0005886:plasma membrane;GO:0005737:cytoplasm;GO:0016020:membrane;	GO:0019904:protein domain specific binding;	K04215	;ko04080 Neuroactive ligand-receptor interaction;ko04915 Estrogen signaling pathway;ko05032 Morphine addiction;
ENSMUSG00000030257	9852	229	1.21	201	1.16	90	0.42	57	0.34	140.768794273194	0.352668120943925	-1.50361692409834	0.278647907195671	-5.39611777181758	6.80982565208492e-08	2.63691582194621e-06	Down	6	112694932	112924227	-	Srgap3	SLIT-ROBO Rho GTPase activating protein 3 [Source:MGI Symbol%3BAcc:MGI:2152938]	GO:0030336:negative regulation of cell migration;GO:0007165:signal transduction;	GO:0005737:cytoplasm;	GO:0005096:GTPase activator activity;	K07526	;ko04360 Axon guidance;
ENSMUSG00000106037	346	956	143.44	944	155.26	2425	322.51	1389	239.09	1406.05923891437	2.05065606409071	1.03608554338322	0.192246041573155	5.38937257123684	7.07040922070233e-08	2.73092329950251e-06	Ups	3	119503165	119503510	+	Gm4332	predicted gene 4332 [Source:MGI Symbol%3BAcc:MGI:3782515]	GO:0002181:cytoplasmic translation;GO:1901798:positive regulation of signal transduction by p53 class mediator;GO:0006412:translation;	GO:0005829:cytosol;GO:0022626:cytosolic ribosome;GO:0022627:cytosolic small ribosomal subunit;GO:0070062:extracellular exosome;GO:0016020:membrane;GO:0005654:nucleoplasm;GO:0015935:small ribosomal subunit;GO:0045202:synapse;	GO:0097371:MDM2/MDM4 family protein binding;GO:0003723:RNA binding;GO:0003735:structural constituent of ribosome;	K02969	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000025264	3805	591	8.06	437	6.54	1170	14.15	819	12.82	745.928588498816	2.00244768863587	1.00176455457837	0.186013451229981	5.38544147186332	7.22670486251461e-08	2.78427870255776e-06	Ups	X	149870090	149879539	-	Tsr2	TSR2 20S rRNA accumulation [Source:MGI Symbol%3BAcc:MGI:1916749]	GO:0000462:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);	-	-	K14800	-
ENSMUSG00000120352	1737	36	1.08	29	0.95	127	3.36	109	3.74	75.3377808267119	3.7849868864206	1.92028830181504	0.359336478286093	5.34398375298309	9.09257215427396e-08	3.4769451724099e-06	Ups	4	63327198	63328934	-	-	novel transcript	-	-	-	-	-
ENSMUSG00000002565	2999	33	0.57	34	0.65	129	1.98	110	2.18	76.6168294204178	3.71022956489312	1.89150845420097	0.354340868907427	5.33810412564952	9.39235166534343e-08	3.56974313175568e-06	Ups	12	40109768	40184227	-	Scin	scinderin [Source:MGI Symbol%3BAcc:MGI:1306794]	GO:0051693:actin filament capping;GO:0051014:actin filament severing;GO:0008154:actin polymerization or depolymerization;GO:0051016:barbed-end actin filament capping;GO:0030031:cell projection assembly;GO:0007417:central nervous system development;GO:0008285:negative regulation of cell proliferation;GO:0051127:positive regulation of actin nucleation;GO:0043065:positive regulation of apoptotic process;GO:0045654:positive regulation of megakaryocyte differentiation;GO:0032330:regulation of chondrocyte differentiation;GO:0042989:sequestering of actin monomers;	GO:0015629:actin cytoskeleton;GO:0005903:brush border;GO:0030054:cell junction;GO:0042995:cell projection;GO:0005737:cytoplasm;GO:0005886:plasma membrane;GO:0002102:podosome;GO:0032991:macromolecular complex;	GO:0051015:actin filament binding;GO:0005509:calcium ion binding;GO:0005546:phosphatidylinositol-4,5-bisphosphate binding;	K05768	;ko04666 Fc gamma R-mediated phagocytosis;ko04810 Regulation of actin cytoskeleton;ko05203 Viral carcinogenesis;
ENSMUSG00000026853	5388	243	2.34	271	2.86	115	0.98	74	0.82	172.031392070024	0.378245362492455	-1.40260570061495	0.262867123785268	-5.33579734284579	9.51256016630074e-08	3.60161969358162e-06	Down	2	30290483	30305825	-	Crat	carnitine acetyltransferase [Source:MGI Symbol%3BAcc:MGI:109501]	GO:0019254:carnitine metabolic process, CoA-linked;GO:0033540:fatty acid beta-oxidation using acyl-CoA oxidase;GO:0006631:fatty acid metabolic process;GO:0051791:medium-chain fatty acid metabolic process;GO:0046459:short-chain fatty acid metabolic process;	GO:0005783:endoplasmic reticulum;GO:0005743:mitochondrial inner membrane;GO:0005739:mitochondrion;GO:0005777:peroxisome;	GO:0003997:acyl-CoA oxidase activity;GO:0004092:carnitine O-acetyltransferase activity;GO:0008458:carnitine O-octanoyltransferase activity;	K00624	;ko04146 Peroxisome;
ENSMUSG00000028329	1894	241	6.61	284	8.53	98	2.38	95	2.99	176.758705964088	0.383212297123849	-1.3837842375843	0.260080761074504	-5.32059438717149	1.03428770548306e-07	3.88719795977382e-06	Down	4	46155347	46196311	-	Xpa	xeroderma pigmentosum%2C complementation group A [Source:MGI Symbol%3BAcc:MGI:99135]	GO:0006284:base-excision repair;GO:0006281:DNA repair;GO:0008630:intrinsic apoptotic signaling pathway in response to DNA damage;GO:0035264:multicellular organism growth;GO:0006289:nucleotide-excision repair;GO:1901255:nucleotide-excision repair involved in interstrand cross-link repair;GO:0000715:nucleotide-excision repair, DNA damage recognition;GO:0033683:nucleotide-excision repair, DNA incision;GO:0060261:positive regulation of transcription initiation from RNA polymerase II promoter;GO:0034504:protein localization to nucleus;GO:0010506:regulation of autophagy;GO:0006979:response to oxidative stress;GO:0009636:response to toxic substance;GO:0009411:response to UV;GO:0009650:UV protection;GO:0070914:UV-damage excision repair;	GO:0005737:cytoplasm;GO:0045171:intercellular bridge;GO:0005654:nucleoplasm;GO:0000110:nucleotide-excision repair factor 1 complex;GO:0005634:nucleus;	GO:0003684:damaged DNA binding;GO:0046872:metal ion binding;GO:0019904:protein domain specific binding;GO:0042803:protein homodimerization activity;	K10847	;ko01524 Platinum drug resistance;ko03420 Nucleotide excision repair;
ENSMUSG00000111291	2420	133	2.85	127	2.99	39	0.74	31	0.76	80.6804669702229	0.27952368262979	-1.8389575743766	0.345780538612239	-5.31827957049607	1.04753026701906e-07	3.92697206719955e-06	Down	9	44201341	44203760	-	Gm48604	predicted gene%2C 48604 [Source:MGI Symbol%3BAcc:MGI:6098186]	-	-	-	-	-
ENSMUSG00000036879	7417	821	5.75	783	6.01	299	1.86	380	3.05	563.833890684879	0.448082367510598	-1.15816413877303	0.217787948215448	-5.31785228826026	1.04999253133678e-07	3.92697206719955e-06	Down	8	86567588	86788005	+	Phkb	phosphorylase kinase beta [Source:MGI Symbol%3BAcc:MGI:97578]	GO:0005977:glycogen metabolic process;GO:0006468:protein phosphorylation;GO:0006091:generation of precursor metabolites and energy;	GO:0005964:phosphorylase kinase complex;GO:0005886:plasma membrane;GO:0005829:cytosol;	GO:0005516:calmodulin binding;	K07190	;ko04020 Calcium signaling pathway;ko04910 Insulin signaling pathway;ko04922 Glucagon signaling pathway;
ENSMUSG00000026509	6345	440	3.60	449	4.03	212	1.54	197	1.85	319.542454414295	0.479868642737557	-1.05928855240019	0.199748350531043	-5.30311539286313	1.1384290823669e-07	4.22679698523342e-06	Down	1	182294825	182345173	-	Capn2	calpain 2 [Source:MGI Symbol%3BAcc:MGI:88264]	GO:0048266:behavioral response to pain;GO:0001824:blastocyst development;GO:0071230:cellular response to amino acid stimulus;GO:0035458:cellular response to interferon-beta;GO:0071222:cellular response to lipopolysaccharide;GO:0007565:female pregnancy;GO:0007520:myoblast fusion;GO:0010666:positive regulation of cardiac muscle cell apoptotic process;GO:1901741:positive regulation of myoblast fusion;GO:1901216:positive regulation of neuron death;GO:2001247:positive regulation of phosphatidylcholine biosynthetic process;GO:0016540:protein autoprocessing;GO:0006508:proteolysis;GO:0051603:proteolysis involved in cellular protein catabolic process;GO:0051493:regulation of cytoskeleton organization;GO:0032675:regulation of interleukin-6 production;GO:0042542:response to hydrogen peroxide;GO:0001666:response to hypoxia;	GO:0042995:cell projection;GO:0000785:chromatin;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0030425:dendrite;GO:0005783:endoplasmic reticulum;GO:0009897:external side of plasma membrane;GO:0005925:focal adhesion;GO:0005794:Golgi apparatus;GO:0005764:lysosome;GO:0016020:membrane;GO:0045121:membrane raft;GO:0043025:neuronal cell body;GO:0005634:nucleus;GO:0097038:perinuclear endoplasmic reticulum;GO:0005886:plasma membrane;GO:0031143:pseudopodium;GO:0005758:mitochondrial intermembrane space;	GO:0005509:calcium ion binding;GO:0004198:calcium-dependent cysteine-type endopeptidase activity;GO:0008092:cytoskeletal protein binding;GO:0019899:enzyme binding;GO:0008233:peptidase activity;GO:0044877:macromolecular complex binding;	K03853	;ko04141 Protein processing in endoplasmic reticulum;ko04210 Apoptosis;ko04217 Necroptosis;ko04218 Cellular senescence;ko04510 Focal adhesion;ko05010 Alzheimer disease;ko05022 Pathways of neurodegeneration - multiple diseases;ko05131 Shigellosis;
ENSMUSG00000034593	14803	5745	20.15	5897	22.67	2111	6.56	2848	11.46	4106.7991229727	0.452645973966988	-1.14354497239971	0.215815119529549	-5.29872501469085	1.16614103788309e-07	4.3192286654346e-06	Down	9	74978297	75130970	+	Myo5a	myosin VA [Source:MGI Symbol%3BAcc:MGI:105976]	GO:0007015:actin filament organization;GO:0030048:actin filament-based movement;GO:0032869:cellular response to insulin stimulus;GO:0032402:melanosome transport;GO:0006892:post-Golgi vesicle-mediated transport;GO:0072659:protein localization to plasma membrane;GO:0015031:protein transport;GO:0030050:vesicle transport along actin filament;GO:0016192:vesicle-mediated transport;	GO:0015629:actin cytoskeleton;GO:0042641:actomyosin;GO:0042642:actomyosin, myosin complex part;GO:0030424:axon;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0070062:extracellular exosome;GO:0032433:filopodium tip;GO:0030426:growth cone;GO:0032593:insulin-responsive compartment;GO:0042470:melanosome;GO:0016020:membrane;GO:0016459:myosin complex;GO:0043005:neuron projection;GO:0001726:ruffle;	GO:0003779:actin binding;GO:0051015:actin filament binding;GO:0005524:ATP binding;GO:0043008:ATP-dependent protein binding;GO:0005516:calmodulin binding;GO:0000146:microfilament motor activity;GO:0003723:RNA binding;GO:0031267:small GTPase binding;	K10357	;ko05130 Pathogenic Escherichia coli infection;
ENSMUSG00000036768	11020	3633	17.11	3473	17.93	1516	6.33	1829	9.88	2582.54070231759	0.497987954772456	-1.00581724777514	0.189925768112759	-5.29584404354223	1.18467916260689e-07	4.37731813961785e-06	Down	9	122780111	122847798	+	Kif15	kinesin family member 15 [Source:MGI Symbol%3BAcc:MGI:1098258]	GO:0007018:microtubule-based movement;	GO:0005737:cytoplasm;GO:0005871:kinesin complex;GO:0005874:microtubule;GO:0005819:spindle;	GO:0005524:ATP binding;GO:0008017:microtubule binding;GO:0003777:microtubule motor activity;	K10400	-
ENSMUSG00000035367	6568	852	6.73	824	7.14	1472	10.31	1711	15.51	1222.44374047063	2.0053114297032	1.00382630810067	0.189696582050162	5.2917469426794	1.2115345770334e-07	4.46578634717071e-06	Ups	13	58550062	58558962	+	Rmi1	RecQ mediated genome instability 1 [Source:MGI Symbol%3BAcc:MGI:1921636]	GO:0006260:DNA replication;GO:0000724:double-strand break repair via homologous recombination;GO:0042593:glucose homeostasis;GO:0035264:multicellular organism growth;GO:0002023:reduction of food intake in response to dietary excess;GO:0000712:resolution of meiotic recombination intermediates;GO:0002021:response to dietary excess;GO:0009749:response to glucose;	GO:0016604:nuclear body;GO:0005654:nucleoplasm;GO:0031422:RecQ helicase-Topo III complex;	GO:0000166:nucleotide binding;	K10990	;ko03460 Fanconi anemia pathway;
ENSMUSG00000078942	6827	243	1.85	224	1.87	77	0.52	87	0.76	155.196845498877	0.36901859456756	-1.43823458045937	0.272275304520097	-5.28228067908821	1.27585528867606e-07	4.68037440109059e-06	Down	13	100417629	100454182	-	Naip6	NLR family%2C apoptosis inhibitory protein 6 [Source:MGI Symbol%3BAcc:MGI:1298222]	GO:0071391:cellular response to estrogen stimulus;GO:0042742:defense response to bacterium;GO:0016045:detection of bacterium;GO:0006954:inflammatory response;GO:0045087:innate immune response;GO:0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0070269:pyroptosis;	GO:0005737:cytoplasm;GO:0072557:IPAF inflammasome complex;GO:0043005:neuron projection;GO:0043025:neuronal cell body;GO:0043204:perikaryon;	GO:0005524:ATP binding;GO:0043027:cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0046872:metal ion binding;	K12807	;ko04621 NOD-like receptor signaling pathway;ko05130 Pathogenic Escherichia coli infection;ko05131 Shigellosis;ko05132 Salmonella infection;ko05134 Legionellosis;
ENSMUSG00000068758	2967	262	4.58	258	4.95	111	1.72	43	0.86	163.696500708635	0.299732468622607	-1.7382527221349	0.329347357578728	-5.2778705586529	1.30693728666503e-07	4.78295378370443e-06	Down	14	8113752	8123488	-	Il3ra	interleukin 3 receptor%2C alpha chain [Source:MGI Symbol%3BAcc:MGI:96553]	GO:0019221:cytokine-mediated signaling pathway;GO:0038156:interleukin-3-mediated signaling pathway;	GO:0012505:endomembrane system;GO:0009897:external side of plasma membrane;GO:0016021:integral component of membrane;GO:0043235:receptor complex;	GO:0019955:cytokine binding;GO:0004896:cytokine receptor activity;	K04737	;ko04060 Cytokine-cytokine receptor interaction;ko04151 PI3K-Akt signaling pathway;ko04210 Apoptosis;ko04630 JAK-STAT signaling pathway;ko04640 Hematopoietic cell lineage;ko05200 Pathways in cancer;
ENSMUSG00000030714	1802	221	6.37	210	6.63	563	14.38	355	11.73	333.004109235873	2.18858147368538	1.12999609176494	0.214276391946146	5.27354451650905	1.33813776046056e-07	4.88547724259578e-06	Ups	7	126248481	126272097	+	Sgf29	SAGA complex associated factor 29 [Source:MGI Symbol%3BAcc:MGI:1922815]	GO:0016573:histone acetylation;GO:0043966:histone H3 acetylation;	GO:0005671:Ada2/Gcn5/Ada3 transcription activator complex;GO:0005634:nucleus;GO:0000124:SAGA complex;GO:0070461:SAGA-type complex;	GO:0019899:enzyme binding;GO:0035064:methylated histone binding;GO:0047485:protein N-terminus binding;	K11364	-
ENSMUSG00000036853	3467	211	3.16	216	3.55	73	0.97	76	1.31	141.663321257727	0.365121219316447	-1.45355258028317	0.275823047563236	-5.26987354075235	1.3651778023582e-07	4.96057735103332e-06	Down	3	145823205	145847561	+	Mcoln3	mucolipin 3 [Source:MGI Symbol%3BAcc:MGI:1890500]	GO:0042491:auditory receptor cell differentiation;GO:0007626:locomotory behavior;	GO:0000421:autophagosome membrane;GO:0005737:cytoplasm;GO:0031901:early endosome membrane;GO:0016021:integral component of membrane;GO:0031902:late endosome membrane;GO:0005765:lysosomal membrane;GO:0016020:membrane;GO:0005886:plasma membrane;GO:0060171:stereocilium membrane;	GO:0008289:lipid binding;GO:0072345:NAADP-sensitive calcium-release channel activity;	K04994	;ko04020 Calcium signaling pathway;
ENSMUSG00000037108	5697	363	3.31	347	3.47	666	5.38	832	8.70	557.494389168125	2.23455037214564	1.15998456691937	0.220458781659811	5.26168455702228	1.4274150892378e-07	5.16226013640858e-06	Ups	5	137786060	137820883	+	Zcwpw1	zinc finger%2C CW type with PWWP domain 1 [Source:MGI Symbol%3BAcc:MGI:2685899]	GO:0030154:cell differentiation;GO:0007129:synapsis;GO:0007127:meiosis I;GO:0045911:positive regulation of DNA recombination;GO:2000781:positive regulation of double-strand break repair;GO:0007283:spermatogenesis;	GO:0005634:nucleus;GO:0001741:XY body;	GO:0008327:methyl-CpG binding;GO:0035064:methylated histone binding;GO:0008270:zinc ion binding;	-	-
ENSMUSG00000024143	4151	1056	13.21	1444	19.80	563	6.24	559	8.02	894.862177429167	0.46803914136632	-1.09529890975003	0.208340852572935	-5.25724502047239	1.46229430978412e-07	5.27595786970111e-06	Down	17	87270510	87307497	+	Rhoq	ras homolog family member Q [Source:MGI Symbol%3BAcc:MGI:1931553]	GO:0030036:actin cytoskeleton organization;GO:0016477:cell migration;GO:0030031:cell projection assembly;GO:0032869:cellular response to insulin stimulus;GO:0030866:cortical actin cytoskeleton organization;GO:0006897:endocytosis;GO:0046039:GTP metabolic process;GO:0008286:insulin receptor signaling pathway;GO:0046325:negative regulation of glucose import;GO:1903077:negative regulation of protein localization to plasma membrane;GO:0051491:positive regulation of filopodium assembly;GO:0046326:positive regulation of glucose import;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0008360:regulation of cell shape;GO:0007264:small GTPase mediated signal transduction;GO:0032956:regulation of actin cytoskeleton organization;	GO:0005884:actin filament;GO:0005737:cytoplasm;GO:0045121:membrane raft;GO:0005886:plasma membrane;GO:0070062:extracellular exosome;GO:0030660:Golgi-associated vesicle membrane;	GO:0032427:GBD domain binding;GO:0005525:GTP binding;GO:0003924:GTPase activity;GO:0005522:profilin binding;	K07194	;ko04910 Insulin signaling pathway;
ENSMUSG00000032743	17086	321	0.98	352	1.17	165	0.44	121	0.42	235.252838111958	0.439090289531073	-1.18741046522881	0.225985722314863	-5.25436055457701	1.48539637018702e-07	5.33420794858263e-06	Down	7	125307060	125473965	+	Katnip	katanin interacting protein [Source:MGI Symbol%3BAcc:MGI:2442760]	-	GO:0042995:cell projection;GO:0005737:cytoplasm;GO:0005856:cytoskeleton;GO:0005576:extracellular region;GO:0005615:extracellular space;	-	-	-
ENSMUSG00000029919	6425	452	3.65	410	3.63	106	0.76	174	1.61	281.85962793459	0.347192562272166	-1.52619205288837	0.290945889018769	-5.24562164475166	1.55756251253812e-07	5.58029522599521e-06	Down	6	65094277	65121892	-	Hpgds	hematopoietic prostaglandin D synthase [Source:MGI Symbol%3BAcc:MGI:1859384]	GO:0006749:glutathione metabolic process;GO:2000255:negative regulation of male germ cell proliferation;GO:0001516:prostaglandin biosynthetic process;GO:0006693:prostaglandin metabolic process;	GO:0005829:cytosol;GO:0043231:intracellular membrane-bounded organelle;GO:0005654:nucleoplasm;	GO:0005509:calcium ion binding;GO:0004364:glutathione transferase activity;GO:0000287:magnesium ion binding;GO:0004667:prostaglandin-D synthase activity;GO:0042803:protein homodimerization activity;	K01830	;ko00590 Arachidonic acid metabolism;ko01100 Metabolic pathways;
ENSMUSG00000031441	11150	73	0.34	64	0.33	210	0.87	158	0.84	125.550521856087	2.78370066321301	1.47700408370236	0.28167435917886	5.24365827265264	1.5742364665367e-07	5.62688624192862e-06	Ups	8	12807014	12918728	+	Atp11a	ATPase%2C class VI%2C type 11A [Source:MGI Symbol%3BAcc:MGI:1354735]	GO:0001701:in utero embryonic development;GO:0045332:phospholipid translocation;GO:0010831:positive regulation of myotube differentiation;	GO:0005769:early endosome;GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0005887:integral component of plasma membrane;GO:0043231:intracellular membrane-bounded organelle;GO:1990531:Lem3p-Dnf1p complex;GO:0005886:plasma membrane;GO:0055037:recycling endosome;GO:0005802:trans-Golgi network;GO:0005765:lysosomal membrane;GO:0016020:membrane;GO:0035579:specific granule membrane;GO:0070821:tertiary granule membrane;	GO:0005524:ATP binding;GO:0000287:magnesium ion binding;GO:0090555:phosphatidylethanolamine-translocating ATPase activity;	K01530	-
ENSMUSG00000054342	5115	566	5.74	493	5.48	299	2.69	212	2.47	384.422194749645	0.499207656590291	-1.00228803320296	0.191467876790756	-5.23475817459604	1.6520101006893e-07	5.86387103795597e-06	Down	7	24069688	24086115	+	Kcnn4	potassium intermediate/small conductance calcium-activated channel%2C subfamily N%2C member 4 [Source:MGI Symbol%3BAcc:MGI:1277957]	GO:0006820:anion transport;GO:0006816:calcium ion transport;GO:0006884:cell volume homeostasis;GO:0002376:immune system process;GO:0006811:ion transport;GO:0045332:phospholipid translocation;GO:0050714:positive regulation of protein secretion;GO:0050862:positive regulation of T cell receptor signaling pathway;GO:0097623:potassium ion export across plasma membrane;GO:0071805:potassium ion transmembrane transport;GO:0006813:potassium ion transport;GO:0046541:saliva secretion;GO:0030322:stabilization of membrane potential;GO:0006952:defense response;GO:1901381:positive regulation of potassium ion transmembrane transport;	GO:0016324:apical plasma membrane;GO:0016323:basolateral plasma membrane;GO:0005887:integral component of plasma membrane;GO:0045121:membrane raft;GO:0043005:neuron projection;GO:0043025:neuronal cell body;GO:0005886:plasma membrane;GO:0031982:vesicle;GO:0008076:voltage-gated potassium channel complex;	GO:0015269:calcium-activated potassium channel activity;GO:0005516:calmodulin binding;GO:0022894:Intermediate conductance calcium-activated potassium channel activity;GO:0005267:potassium channel activity;GO:0019903:protein phosphatase binding;GO:0016286:small conductance calcium-activated potassium channel activity;	K04945	;ko04911 Insulin secretion;ko04929 GnRH secretion;ko04970 Salivary secretion;ko04974 Protein digestion and absorption;
ENSMUSG00000051811	1108	13	0.61	11	0.56	167	6.94	42	2.26	55.9127228760937	8.649317705867	3.11258633145623	0.594805434617023	5.23294870945544	1.66827042861972e-07	5.90791195206808e-06	Ups	7	4754791	4756093	-	Cox6b2	cytochrome c oxidase subunit 6B2 [Source:MGI Symbol%3BAcc:MGI:3044182]	GO:0006119:oxidative phosphorylation;	GO:0030061:mitochondrial crista;GO:0005739:mitochondrion;GO:0045277:respiratory chain complex IV;	-	K02267	;ko00190 Oxidative phosphorylation;ko01100 Metabolic pathways;ko04260 Cardiac muscle contraction;ko04714 Thermogenesis;ko04932 Non-alcoholic fatty liver disease;ko05010 Alzheimer disease;ko05012 Parkinson disease;ko05014 Amyotrophic lateral sclerosis;ko05016 Huntington disease;ko05020 Prion disease;ko05022 Pathways of neurodegeneration - multiple diseases;
ENSMUSG00000026073	1908	109	2.97	154	4.59	488	11.77	255	7.96	247.464779704196	2.86532613612798	1.51869935824783	0.29047261177422	5.22837368029827	1.710076103424e-07	6.02811654480544e-06	Ups	1	40113239	40164391	+	Il1r2	interleukin 1 receptor%2C type II [Source:MGI Symbol%3BAcc:MGI:96546]	GO:1900016:negative regulation of cytokine production involved in inflammatory response;GO:0032690:negative regulation of interleukin-1 alpha production;GO:2000660:negative regulation of interleukin-1-mediated signaling pathway;GO:0010955:negative regulation of protein processing;	GO:0005737:cytoplasm;GO:0005576:extracellular region;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0019966:interleukin-1 binding;GO:0004908:interleukin-1 receptor activity;GO:0004910:interleukin-1, Type II, blocking receptor activity;	K04387	;ko04060 Cytokine-cytokine receptor interaction;ko04640 Hematopoietic cell lineage;ko05146 Amoebiasis;ko05166 Human T-cell leukemia virus 1 infection;ko05202 Transcriptional misregulation in cancer;ko05215 Prostate cancer;ko05418 Fluid shear stress and atherosclerosis;
ENSMUSG00000063455	13450	38	0.15	34	0.14	143	0.49	104	0.46	79.3388185165349	3.54956442375521	1.82764199863331	0.349591754318237	5.22793222682703	1.71416318108691e-07	6.02866472907951e-06	Ups	6	38100109	38230944	-	D630045J12Rik	RIKEN cDNA D630045J12 gene [Source:MGI Symbol%3BAcc:MGI:2669829]	-	GO:0016021:integral component of membrane;GO:0032391:photoreceptor connecting cilium;	-	-	-
ENSMUSG00000068220	903	279	16.04	273	17.20	133	6.78	76	5.01	185.716251680079	0.388436959150382	-1.36424761749226	0.26164870604301	-5.21404305079193	1.84768557704876e-07	6.4711614684175e-06	Down	15	78810925	78814665	+	Lgals1	lectin%2C galactose binding%2C soluble 1 [Source:MGI Symbol%3BAcc:MGI:96777]	GO:0006915:apoptotic process;GO:0071333:cellular response to glucose stimulus;GO:0071407:cellular response to organic cyclic compound;GO:0007157:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0045445:myoblast differentiation;GO:0010812:negative regulation of cell-substrate adhesion;GO:0010977:negative regulation of neuron projection development;GO:0002317:plasma cell differentiation;GO:0034120:positive regulation of erythrocyte aggregation;GO:0046598:positive regulation of viral entry into host cell;GO:0048678:response to axon injury;GO:0042493:response to drug;GO:0035900:response to isolation stress;GO:0031295:T cell costimulation;	GO:0009986:cell surface;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005576:extracellular region;GO:0005615:extracellular space;GO:0005634:nucleus;	GO:0030246:carbohydrate binding;GO:0005534:galactose binding;GO:0042802:identical protein binding;GO:0030395:lactose binding;GO:0043236:laminin binding;	K06830	-
ENSMUSG00000024669	4928	287	3.02	221	2.55	114	1.06	71	0.86	168.863110903958	0.375867893005606	-1.41170241063149	0.27075387987825	-5.21396927448018	1.84842097506643e-07	6.4711614684175e-06	Down	19	10694480	10716366	-	Cd5	CD5 antigen [Source:MGI Symbol%3BAcc:MGI:88340]	GO:0097190:apoptotic signaling pathway;GO:0031295:T cell costimulation;	GO:0009897:external side of plasma membrane;GO:0005886:plasma membrane;GO:0044214:spanning component of plasma membrane;	GO:0005044:scavenger receptor activity;	K06455	;ko04640 Hematopoietic cell lineage;
ENSMUSG00000009687	4192	583	7.22	576	7.82	316	3.47	154	2.19	396.865074917486	0.412510208503213	-1.27749827231746	0.245711277610918	-5.19918452558928	2.0016474013421e-07	6.94417675388681e-06	Down	7	30732147	30741906	-	Fxyd5	FXYD domain-containing ion transport regulator 5 [Source:MGI Symbol%3BAcc:MGI:1201785]	GO:0006811:ion transport;GO:2000649:regulation of sodium ion transmembrane transporter activity;	GO:0016021:integral component of membrane;	GO:0003779:actin binding;GO:0045296:cadherin binding;GO:0017080:sodium channel regulator activity;	K13362	-
ENSMUSG00000045211	4440	204	2.39	181	2.32	78	0.81	57	0.76	127.12306720225	0.363370122097059	-1.46048829522311	0.281110429477718	-5.19542550568682	2.04252115590956e-07	7.06998180693391e-06	Down	14	70815077	70820128	+	Nudt18	nudix (nucleoside diphosphate linked moiety X)-type motif 18 [Source:MGI Symbol%3BAcc:MGI:2385853]	GO:0046057:dADP catabolic process;GO:0046067:dGDP catabolic process;GO:0046712:GDP catabolic process;	-	GO:0044717:8-hydroxy-dADP phosphatase activity;GO:0044715:8-oxo-dGDP phosphatase activity;GO:0044716:8-oxo-GDP phosphatase activity;GO:0000287:magnesium ion binding;	K17817	-
ENSMUSG00000034520	5003	7	0.07	11	0.13	73	0.67	55	0.65	36.5237046917903	7.34209519086182	2.87619181921736	0.553676624147889	5.19471419557189	2.05034583474928e-07	7.08108176352374e-06	Ups	11	102690405	102710526	-	Gjc1	gap junction protein%2C gamma 1 [Source:MGI Symbol%3BAcc:MGI:95718]	GO:0086053:AV node cell to bundle of His cell communication by electrical coupling;GO:0048738:cardiac muscle tissue development;GO:0048468:cell development;GO:0007267:cell-cell signaling;GO:0007268:synaptic transmission;GO:0016264:gap junction assembly;GO:0007507:heart development;GO:0001570:vasculogenesis;GO:0007601:visual perception;	GO:0005922:connexon complex;GO:0005921:gap junction;GO:0016021:integral component of membrane;GO:0045202:synapse;	GO:0005243:gap junction channel activity;GO:0086077:gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling;GO:0005216:ion channel activity;	K07616	-
ENSMUSG00000000958	3315	215	3.37	216	3.71	91	1.26	70	1.26	145.068700154984	0.387129848768169	-1.36911054724255	0.26409016252623	-5.18425424917737	2.16880906199874e-07	7.45661842078222e-06	Down	14	54606899	54655237	-	Slc7a7	solute carrier family 7 (cationic amino acid transporter%2C y+ system)%2C member 7 [Source:MGI Symbol%3BAcc:MGI:1337120]	GO:0000821:regulation of arginine metabolic process;	GO:0016323:basolateral plasma membrane;GO:0016021:integral component of membrane;	GO:0015174:basic amino acid transmembrane transporter activity;GO:0015179:L-amino acid transmembrane transporter activity;	K13867	;ko04974 Protein digestion and absorption;
ENSMUSG00000104435	4718	96	1.06	75	0.90	309	3.01	171	2.16	160.100405689596	2.87501160283732	1.52356777842991	0.29403419017152	5.18160074357736	2.19989715248362e-07	7.54658231234538e-06	Ups	1	189612132	189616849	+	Gm37422	predicted gene%2C 37422 [Source:MGI Symbol%3BAcc:MGI:5610650]	-	-	-	-	-
ENSMUSG00000097908	4803	530	5.73	699	8.28	297	2.85	255	3.16	438.886396083087	0.465615757798573	-1.10278821079674	0.21322129494251	-5.17203598774727	2.31556972154386e-07	7.92565761387356e-06	Down	5	136947964	136965968	+	4933404O12Rik	RIKEN cDNA 4933404O12 gene [Source:MGI Symbol%3BAcc:MGI:1914002]	-	-	-	-	-
ENSMUSG00000020834	1967	52	1.37	37	1.07	163	3.81	120	3.63	92.451563344971	3.29823311684012	1.72169337106877	0.332998560792316	5.17027270920415	2.3375262357415e-07	7.98299048972387e-06	Ups	11	77923106	77928692	+	Dhrs13	dehydrogenase/reductase (SDR family) member 13 [Source:MGI Symbol%3BAcc:MGI:1917701]	GO:0042574:retinal metabolic process;	GO:0005576:extracellular region;GO:0005743:mitochondrial inner membrane;	GO:0052650:NADP-retinol dehydrogenase activity;	K11169	-
ENSMUSG00000045868	9005	181	1.04	114	0.72	39	0.20	38	0.25	90.7108968599264	0.274062560070899	-1.86742284111023	0.361319082617496	-5.16834822999687	2.36171959758462e-07	8.04769073541391e-06	Down	7	105755763	105814533	-	Gvin1	GTPase%2C very large interferon inducible 1 [Source:MGI Symbol%3BAcc:MGI:1921808]	-	GO:0005829:cytosol;GO:0005634:nucleus;	GO:0005525:GTP binding;	-	-
ENSMUSG00000031258	3024	250	4.29	294	5.53	109	1.66	102	2.01	185.858902120021	0.403859948844712	-1.30807301512056	0.253117040080873	-5.16785837374925	2.36791628823095e-07	8.05091537998524e-06	Down	X	133049792	133062825	-	Xkrx	X-linked Kx blood group related%2C X-linked [Source:MGI Symbol%3BAcc:MGI:3584011]	-	GO:0016021:integral component of membrane;	-	-	-
ENSMUSG00000041189	2531	136	2.79	173	3.89	49	0.89	42	0.99	98.2369338996702	0.305378994493657	-1.71132726517584	0.332116947045608	-5.1527851270439	2.56645975541037e-07	8.66830261882435e-06	Down	11	69674862	69686769	-	Chrnb1	cholinergic receptor%2C nicotinic%2C beta polypeptide 1 (muscle) [Source:MGI Symbol%3BAcc:MGI:87890]	GO:0035095:behavioral response to nicotine;GO:0006812:cation transport;GO:0007268:synaptic transmission;GO:0034220:ion transmembrane transport;GO:0055001:muscle cell development;GO:0006936:muscle contraction;GO:0050877:neurological system process;GO:0007274:neuromuscular synaptic transmission;GO:0001941:postsynaptic membrane organization;GO:0042391:regulation of membrane potential;GO:0007165:signal transduction;GO:0003009:skeletal muscle contraction;GO:0007271:synaptic transmission, cholinergic;	GO:0005892:acetylcholine-gated channel complex;GO:0005887:integral component of plasma membrane;GO:0031594:neuromuscular junction;GO:0043005:neuron projection;GO:0005886:plasma membrane;GO:0045202:synapse;	GO:0042166:acetylcholine binding;GO:0015464:acetylcholine receptor activity;GO:0022848:acetylcholine-gated cation channel activity;GO:0015267:channel activity;GO:0015276:ligand-gated ion channel activity;GO:0030594:neurotransmitter receptor activity;	K04812	;ko04080 Neuroactive ligand-receptor interaction;
ENSMUSG00000000884	4219	80	0.98	86	1.16	274	2.99	168	2.37	150.19129031013	2.73046261180992	1.44914540214244	0.281789939604736	5.14264421283152	2.70898349052037e-07	9.07563661832435e-06	Ups	16	18317463	18385429	+	Gnb1l	guanine nucleotide binding protein (G protein)%2C beta polypeptide 1-like [Source:MGI Symbol%3BAcc:MGI:1338057]	GO:0035176:social behavior;	GO:0005737:cytoplasm;	-	-	-
ENSMUSG00000024251	11486	1118	5.05	910	4.51	366	1.47	485	2.51	710.283912128659	0.446217357655132	-1.16418146002356	0.226546513371369	-5.13881870305	2.76470975532544e-07	9.23617851593906e-06	Down	17	84497504	84773633	-	Thada	thyroid adenoma associated [Source:MGI Symbol%3BAcc:MGI:3039623]	GO:0055088:lipid homeostasis;GO:0032471:negative regulation of endoplasmic reticulum calcium ion concentration;GO:0030488:tRNA methylation;	GO:0005829:cytosol;GO:0005783:endoplasmic reticulum;	-	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000097715	5297	360	3.53	399	4.29	175	1.52	162	1.82	269.923073486454	0.462562227200264	-1.11228063448138	0.21690460914954	-5.1279714103011	2.92880905231501e-07	9.7419431688066e-06	Down	13	12629946	12665284	-	Gpr137b-ps	G protein-coupled receptor 137B%2C pseudogene [Source:MGI Symbol%3BAcc:MGI:3710533]	GO:0006914:autophagy;GO:0045779:negative regulation of bone resorption;GO:0045671:negative regulation of osteoclast differentiation;GO:1904263:positive regulation of TORC1 signaling;GO:0010506:regulation of autophagy;GO:0043087:regulation of GTPase activity;GO:0043030:regulation of macrophage activation;	GO:0016021:integral component of membrane;GO:0005765:lysosomal membrane;	-	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000028234	4080	10128	128.87	9521	132.80	25185	284.04	13930	203.34	14440.8137125188	2.03071279210617	1.02198621072999	0.199321639003146	5.12732192972716	2.93892731729026e-07	9.75443971500626e-06	Ups	4	3831334	3835665	-	Rps20	ribosomal protein S20 [Source:MGI Symbol%3BAcc:MGI:1914677]	GO:0002181:cytoplasmic translation;GO:1901798:positive regulation of signal transduction by p53 class mediator;GO:0006412:translation;	GO:0005829:cytosol;GO:0022626:cytosolic ribosome;GO:0022627:cytosolic small ribosomal subunit;GO:0070062:extracellular exosome;GO:0016020:membrane;GO:0005654:nucleoplasm;GO:0015935:small ribosomal subunit;GO:0045202:synapse;GO:0005737:cytoplasm;	GO:0097371:MDM2/MDM4 family protein binding;GO:0003723:RNA binding;GO:0003735:structural constituent of ribosome;	K02969	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000028064	5406	108	1.04	115	1.21	269	2.29	237	2.61	182.142622201684	2.36214086461799	1.24009500140997	0.241980846980457	5.124765108001	2.97908906843402e-07	9.84511891710501e-06	Ups	3	88343266	88368489	-	Sema4a	sema domain%2C immunoglobulin domain (Ig)%2C transmembrane domain (TM) and short cytoplasmic domain%2C (semaphorin) 4A [Source:MGI Symbol%3BAcc:MGI:107560]	GO:0001525:angiogenesis;GO:0007411:axon guidance;GO:0007409:axonogenesis;GO:0050919:negative chemotaxis;GO:0016525:negative regulation of angiogenesis;GO:0048843:negative regulation of axon extension involved in axon guidance;GO:0001755:neural crest cell migration;GO:0030335:positive regulation of cell migration;GO:0008360:regulation of cell shape;GO:0010594:regulation of endothelial cell migration;GO:0071526:semaphorin-plexin signaling pathway;GO:0002292:T cell differentiation involved in immune response;GO:0045063:T-helper 1 cell differentiation;	GO:0005615:extracellular space;GO:0005887:integral component of plasma membrane;	GO:0045499:chemorepellent activity;GO:0030215:semaphorin receptor binding;	K06521	;ko04360 Axon guidance;
ENSMUSG00000070461	3352	107	1.66	104	1.77	32	0.44	16	0.28	63.012549203657	0.23328746824701	-2.0998192842797	0.410417036023557	-5.11630634201836	3.1157686993572e-07	1.02526174326059e-05	Down	2	180625717	180629068	+	9230112E08Rik	RIKEN cDNA 9230112E08 gene [Source:MGI Symbol%3BAcc:MGI:2444774]	-	-	-	-	-
ENSMUSG00000048612	12603	172	0.71	203	0.92	51	0.19	64	0.30	120.815183987281	0.322341705698458	-1.63333723347792	0.319489932300476	-5.11232770847312	3.18213172130817e-07	1.04447695430942e-05	Down	19	37887484	38032025	-	Myof	myoferlin [Source:MGI Symbol%3BAcc:MGI:1919192]	GO:0034605:cellular response to heat;GO:0006071:glycerol metabolic process;GO:0061025:membrane fusion;GO:0055001:muscle cell development;GO:0007520:myoblast fusion;GO:0007009:plasma membrane organization;GO:0001778:plasma membrane repair;GO:0030947:regulation of vascular endothelial growth factor receptor signaling pathway;GO:0033292:T-tubule organization;	GO:0005901:caveola;GO:0031410:cytoplasmic vesicle;GO:0030659:cytoplasmic vesicle membrane;GO:0016021:integral component of membrane;GO:0043231:intracellular membrane-bounded organelle;GO:0031965:nuclear membrane;GO:0005886:plasma membrane;	GO:0046872:metal ion binding;GO:0005543:phospholipid binding;	K18261	-
ENSMUSG00000018750	8117	557	3.56	758	5.31	280	1.59	285	2.09	464.446132675496	0.448405671213554	-1.15712357013401	0.226354712953263	-5.11199239033707	3.187786713296e-07	1.04447695430942e-05	Down	11	69656738	69674849	+	Zbtb4	zinc finger and BTB domain containing 4 [Source:MGI Symbol%3BAcc:MGI:1922830]	GO:0006974:cellular response to DNA damage stimulus;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0045892:negative regulation of transcription, DNA-templated;GO:0006355:regulation of transcription, DNA-templated;	GO:0005694:chromosome;GO:0005829:cytosol;GO:0016604:nuclear body;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001227:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0046872:metal ion binding;GO:0008327:methyl-CpG binding;GO:0010428:methyl-CpNpG binding;GO:0042803:protein homodimerization activity;GO:0019901:protein kinase binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000977:RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565:sequence-specific DNA binding;	K10491	-
ENSMUSG00000053113	2891	25	0.45	55	1.08	209	3.33	120	2.47	101.147147037228	4.17426308854123	2.06152153115718	0.403960261685579	5.10327803669402	3.33819995518869e-07	1.09142767831265e-05	Ups	11	117856905	117860873	-	Socs3	suppressor of cytokine signaling 3 [Source:MGI Symbol%3BAcc:MGI:1201791]	GO:0060670:branching involved in labyrinthine layer morphogenesis;GO:0035556:intracellular signal transduction;GO:0043066:negative regulation of apoptotic process;GO:0050728:negative regulation of inflammatory response;GO:0046627:negative regulation of insulin receptor signaling pathway;GO:0046426:negative regulation of JAK-STAT cascade;GO:0009968:negative regulation of signal transduction;GO:0042532:negative regulation of tyrosine phosphorylation of STAT protein;GO:0046854:phosphatidylinositol phosphorylation;GO:0060674:placenta blood vessel development;GO:0045597:positive regulation of cell differentiation;GO:0016567:protein ubiquitination;GO:0007259:JAK-STAT cascade;GO:0045595:regulation of cell differentiation;GO:0040008:regulation of growth;GO:0001932:regulation of protein phosphorylation;GO:0007165:signal transduction;GO:0060708:spongiotrophoblast differentiation;GO:0060707:trophoblast giant cell differentiation;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005942:phosphatidylinositol 3-kinase complex;	GO:0046935:1-phosphatidylinositol-3-kinase regulator activity;GO:0001784:phosphotyrosine binding;	K04696	;ko04120 Ubiquitin mediated proteolysis;ko04380 Osteoclast differentiation;ko04630 JAK-STAT signaling pathway;ko04668 TNF signaling pathway;ko04910 Insulin signaling pathway;ko04917 Prolactin signaling pathway;ko04920 Adipocytokine signaling pathway;ko04930 Type II diabetes mellitus;ko04931 Insulin resistance;ko04932 Non-alcoholic fatty liver disease;ko04935 Growth hormone synthesis, secretion and action;ko05160 Hepatitis C;ko05164 Influenza A;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000087590	1162	157	7.01	129	6.32	362	14.34	259	13.27	224.706658715811	2.24701383027349	1.16800900427108	0.229435641481383	5.09079145999142	3.56572018619411e-07	1.15840579099789e-05	Ups	18	33927889	33929050	+	Epb41l4aos	erythrocyte membrane protein band 4.1 like 4a%2C opposite strand [Source:MGI Symbol%3BAcc:MGI:1916999]	-	-	-	-	-
ENSMUSG00000024754	8520	225	1.37	193	1.29	78	0.42	75	0.52	140.094995666495	0.382811780599518	-1.38529286707234	0.272308762828799	-5.087213693315	3.63362335738785e-07	1.17796999074388e-05	Down	19	21755706	21835724	+	Cemip2	cell migration inducing hyaluronidase 2 [Source:MGI Symbol%3BAcc:MGI:1890373]	GO:0001525:angiogenesis;GO:0030214:hyaluronan catabolic process;GO:1903670:regulation of sprouting angiogenesis;	GO:0005887:integral component of plasma membrane;GO:0043231:intracellular membrane-bounded organelle;GO:0005886:plasma membrane;	GO:0005509:calcium ion binding;GO:0004415:hyalurononglucosaminidase activity;	-	-
ENSMUSG00000049044	6677	77	0.60	78	0.66	16	0.11	12	0.11	44.6543803388265	0.187201214024161	-2.41733830387119	0.475366936317517	-5.08520496313305	3.67229275726418e-07	1.18799445442804e-05	Down	2	71811584	72087818	+	Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4 [Source:MGI Symbol%3BAcc:MGI:1917723]	GO:0017156:calcium ion-dependent exocytosis;GO:0019933:cAMP-mediated signaling;GO:0030073:insulin secretion;GO:0050805:negative regulation of synaptic transmission;GO:0050714:positive regulation of protein secretion;GO:0014911:positive regulation of smooth muscle cell migration;GO:0050773:regulation of dendrite development;GO:0017157:regulation of exocytosis;GO:0007165:signal transduction;GO:0007264:small GTPase mediated signal transduction;GO:0002250:adaptive immune response;GO:0007186:G-protein coupled receptor signaling pathway;	GO:0016324:apical plasma membrane;GO:0030424:axon;GO:0016323:basolateral plasma membrane;GO:0005903:brush border;GO:0005929:cilium;GO:0044316:cone cell pedicle;GO:0005829:cytosol;GO:0030425:dendrite;GO:0043197:dendritic spine;GO:0060076:excitatory synapse;GO:0030426:growth cone;GO:0043025:neuronal cell body;GO:0001917:photoreceptor inner segment;GO:0001750:photoreceptor outer segment;GO:0005886:plasma membrane;GO:0014069:postsynaptic density;GO:0032991:macromolecular complex;GO:0016020:membrane;	GO:0030552:cAMP binding;GO:0005085:guanyl-nucleotide exchange factor activity;GO:0044877:macromolecular complex binding;GO:0031267:small GTPase binding;	K04351	;ko04015 Rap1 signaling pathway;ko04024 cAMP signaling pathway;ko04072 Phospholipase D signaling pathway;ko04261 Adrenergic signaling in cardiomyocytes;ko04670 Leukocyte transendothelial migration;ko04911 Insulin secretion;
ENSMUSG00000002319	4669	577	6.42	525	6.40	1459	14.38	798	10.18	825.143685328021	2.09077337836441	1.06403669481691	0.209307336799434	5.08360916099423	3.7032958159533e-07	1.19550185351217e-05	Ups	14	55862857	55873414	-	Ipo4	importin 4 [Source:MGI Symbol%3BAcc:MGI:1923001]	GO:0006335:DNA replication-dependent nucleosome assembly;GO:0006336:DNA replication-independent nucleosome assembly;GO:0006606:protein import into nucleus;GO:0042254:ribosome biogenesis;	GO:0000785:chromatin;GO:0005737:cytoplasm;GO:0005634:nucleus;GO:0032991:macromolecular complex;	GO:0061608:nuclear import signal receptor activity;GO:0008139:nuclear localization sequence binding;GO:0031267:small GTPase binding;	-	-
ENSMUSG00000041975	5594	349	3.24	326	3.32	145	1.19	147	1.57	238.028478377303	0.453058501592646	-1.14223074327314	0.224748733470095	-5.08225664117091	3.72977005480396e-07	1.19915469126855e-05	Down	2	70794905	70885927	-	Mettl8	methyltransferase like 8 [Source:MGI Symbol%3BAcc:MGI:2385142]	GO:0045444:fat cell differentiation;GO:0016573:histone acetylation;GO:0080009:mRNA methylation;GO:0007519:skeletal muscle tissue development;GO:0030488:tRNA methylation;	GO:0005737:cytoplasm;GO:0005634:nucleus;	GO:0004402:histone acetyltransferase activity;GO:0008174:mRNA methyltransferase activity;GO:0052735:tRNA (cytosine-3-)-methyltransferase activity;GO:0016427:tRNA (cytosine) methyltransferase activity;	-	-
ENSMUSG00000025959	8131	397	2.53	405	2.83	171	0.97	182	1.33	284.810232101494	0.461456707603113	-1.1157327897162	0.219535976050371	-5.08223212335913	3.73025164820073e-07	1.19915469126855e-05	Down	1	64068606	64161441	-	Klf7	Kruppel-like factor 7 (ubiquitous) [Source:MGI Symbol%3BAcc:MGI:1935151]	GO:0007411:axon guidance;GO:0007409:axonogenesis;GO:0048813:dendrite morphogenesis;GO:0042593:glucose homeostasis;GO:1904178:negative regulation of adipose tissue development;GO:0061179:negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-templated;GO:0045604:regulation of epidermal cell differentiation;GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005829:cytosol;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0003677:DNA binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046872:metal ion binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K09207	-
ENSMUSG00000086938	2652	98	1.92	78	1.67	22	0.38	13	0.29	51.2653698448544	0.205436808798552	-2.28323339758642	0.449509187906541	-5.07939205474291	3.78644593584973e-07	1.21467284477656e-05	Down	19	5456768	5472875	+	4930481A15Rik	RIKEN cDNA 4930481A15 gene [Source:MGI Symbol%3BAcc:MGI:1922181]	-	-	-	-	-
ENSMUSG00000017692	4734	25	0.27	27	0.32	139	1.35	76	0.96	65.7912828377944	4.22205845089451	2.07794655173858	0.410618138516119	5.06053278417707	4.18086561208844e-07	1.32457424164802e-05	Ups	11	80191738	80246781	+	Rhbdl3	rhomboid like 3 [Source:MGI Symbol%3BAcc:MGI:2179276]	-	GO:0016021:integral component of membrane;	GO:0005509:calcium ion binding;GO:0004252:serine-type endopeptidase activity;	K02857	-
ENSMUSG00000024670	7968	81	0.53	62	0.44	10	0.06	12	0.09	40.2257016639962	0.161663122922769	-2.62893747262493	0.520387716865713	-5.05188225513657	4.37477367220442e-07	1.37799214501715e-05	Down	19	10766705	10807422	-	Cd6	CD6 antigen [Source:MGI Symbol%3BAcc:MGI:103566]	GO:0002438:acute inflammatory response to antigenic stimulus;GO:0007157:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0001771:immunological synapse formation;GO:0031663:lipopolysaccharide-mediated signaling pathway;GO:1900017:positive regulation of cytokine production involved in inflammatory response;GO:0001934:positive regulation of protein phosphorylation;GO:0042102:positive regulation of T cell proliferation;GO:0032496:response to lipopolysaccharide;	GO:0009897:external side of plasma membrane;GO:0001772:immunological synapse;GO:0031226:intrinsic component of plasma membrane;GO:0044214:spanning component of plasma membrane;GO:0042101:T cell receptor complex;	GO:0042802:identical protein binding;GO:0001530:lipopolysaccharide binding;GO:0070891:lipoteichoic acid binding;GO:0019901:protein kinase binding;GO:0005044:scavenger receptor activity;	K06456	;ko04514 Cell adhesion molecules;
ENSMUSG00000014554	4611	443	4.99	507	6.26	262	2.61	177	2.29	340.633891669718	0.475522578832818	-1.07241424991767	0.212283177812938	-5.05180985590234	4.37643259830018e-07	1.37799214501715e-05	Down	6	83457199	83483951	-	Dguok	deoxyguanosine kinase [Source:MGI Symbol%3BAcc:MGI:1351602]	GO:0006754:ATP biosynthetic process;GO:0046070:dGTP metabolic process;GO:0042775:mitochondrial ATP synthesis coupled electron transport;GO:0010977:negative regulation of neuron projection development;GO:0006139:nucleobase-containing compound metabolic process;GO:0006468:protein phosphorylation;GO:0046122:purine deoxyribonucleoside metabolic process;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005739:mitochondrion;	GO:0005524:ATP binding;GO:0004136:deoxyadenosine kinase activity;GO:0004138:deoxyguanosine kinase activity;GO:0019136:deoxynucleoside kinase activity;	K00904	;ko00230 Purine metabolism;ko01100 Metabolic pathways;
ENSMUSG00000106617	1749	103	3.06	102	3.32	30	0.79	20	0.68	62.2267834903754	0.251953852091531	-1.98876858122361	0.395884694276321	-5.0236056356235	5.07103119119362e-07	1.58047138792201e-05	Down	5	137611114	137613509	+	Gm36266	predicted gene%2C 36266 [Source:MGI Symbol%3BAcc:MGI:5595425]	-	-	-	-	-
ENSMUSG00000075511	6112	184	1.56	152	1.42	344	2.59	377	3.67	265.613538615038	2.26134837224596	1.17718326373738	0.234578547927985	5.01829035150634	5.21333437610479e-07	1.61824431828321e-05	Ups	15	83238048	83251483	-	1700001L05Rik	RIKEN cDNA 1700001L05 gene [Source:MGI Symbol%3BAcc:MGI:1916541]	-	-	-	-	-
ENSMUSG00000021701	4491	56	0.65	62	0.79	194	1.99	135	1.79	110.945254374896	2.87402353740941	1.52307187709267	0.303746003697415	5.01429437277445	5.32284421321634e-07	1.64889885182746e-05	Ups	13	110531580	110537378	+	Plk2	polo like kinase 2 [Source:MGI Symbol%3BAcc:MGI:1099790]	GO:0000082:G1/S transition of mitotic cell cycle;GO:0060292:long term synaptic depression;GO:0060291:long-term synaptic potentiation;GO:0007613:memory;GO:0000278:mitotic cell cycle;GO:0007052:mitotic spindle organization;GO:0016525:negative regulation of angiogenesis;GO:0043066:negative regulation of apoptotic process;GO:0071866:negative regulation of apoptotic process in bone marrow;GO:2000773:negative regulation of cellular senescence;GO:0061000:negative regulation of dendritic spine development;GO:0018105:peptidyl-serine phosphorylation;GO:0010508:positive regulation of autophagy;GO:0090050:positive regulation of cell migration involved in sprouting angiogenesis;GO:0032436:positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032092:positive regulation of protein binding;GO:0045732:positive regulation of protein catabolic process;GO:0006468:protein phosphorylation;GO:0032486:Rap protein signal transduction;GO:0007265:Ras protein signal transduction;GO:0046599:regulation of centriole replication;GO:0032465:regulation of cytokinesis;GO:0048167:regulation of synaptic plasticity;	GO:0005814:centriole;GO:0005813:centrosome;GO:0000785:chromatin;GO:0005737:cytoplasm;GO:0030425:dendrite;GO:0005634:nucleus;GO:0000922:spindle pole;	GO:0005524:ATP binding;GO:0043008:ATP-dependent protein binding;GO:0004674:protein serine/threonine kinase activity;GO:0044877:macromolecular complex binding;	K08861	;ko04068 FoxO signaling pathway;
ENSMUSG00000027030	4955	126	1.32	104	1.19	328	3.05	211	2.54	189.944726712325	2.4143318504285	1.27162398846379	0.253883921703162	5.00868262918422	5.48038571305041e-07	1.69427892185313e-05	Ups	2	68040789	68302612	-	Stk39	serine/threonine kinase 39 [Source:MGI Symbol%3BAcc:MGI:1858416]	GO:0000187:activation of MAPK activity;GO:0071476:cellular hypotonic response;GO:0038146:chemokine (C-X-C motif) ligand 12 signaling pathway;GO:0035556:intracellular signal transduction;GO:0050801:ion homeostasis;GO:0036438:maintenance of lens transparency;GO:0090188:negative regulation of pancreatic juice secretion;GO:1901380:negative regulation of potassium ion transmembrane transport;GO:1901017:negative regulation of potassium ion transmembrane transporter activity;GO:2000650:negative regulation of sodium ion transmembrane transporter activity;GO:0018105:peptidyl-serine phosphorylation;GO:0018107:peptidyl-threonine phosphorylation;GO:0032414:positive regulation of ion transmembrane transporter activity;GO:1900745:positive regulation of p38MAPK cascade;GO:0043268:positive regulation of potassium ion transport;GO:0010820:positive regulation of T cell chemotaxis;GO:0046777:protein autophosphorylation;GO:0006468:protein phosphorylation;GO:0008217:regulation of blood pressure;GO:0050727:regulation of inflammatory response;GO:0007165:signal transduction;	GO:0016324:apical plasma membrane;GO:0016323:basolateral plasma membrane;GO:0005737:cytoplasm;GO:0005856:cytoskeleton;GO:0005829:cytosol;GO:0019898:extrinsic component of membrane;GO:0043231:intracellular membrane-bounded organelle;GO:0016020:membrane;GO:0005654:nucleoplasm;	GO:0005524:ATP binding;GO:0016301:kinase activity;GO:0019901:protein kinase binding;GO:0004674:protein serine/threonine kinase activity;	K08835	-
ENSMUSG00000068854	2620	164	3.25	137	2.98	47	0.83	47	1.07	96.7920891481784	0.326996203254672	-1.6126542101654	0.322044826095124	-5.00754578087543	5.51284418357221e-07	1.70088436038021e-05	Down	3	96128435	96131054	+	H2bc21	H2B clustered histone 21 [Source:MGI Symbol%3BAcc:MGI:2448415]	-	GO:0000786:nucleosome;GO:0005634:nucleus;	GO:0003677:DNA binding;GO:0046982:protein heterodimerization activity;	K11252	;ko04613 Neutrophil extracellular trap formation;ko05034 Alcoholism;ko05203 Viral carcinogenesis;ko05322 Systemic lupus erythematosus;
ENSMUSG00000027298	6198	55	0.46	45	0.41	204	1.51	113	1.09	102.624265001334	3.24618082567883	1.69874336619643	0.33930936450475	5.00647357221009	5.54362689438182e-07	1.70352654906715e-05	Ups	2	119628214	119648585	+	Tyro3	TYRO3 protein tyrosine kinase 3 [Source:MGI Symbol%3BAcc:MGI:104294]	GO:0043277:apoptotic cell clearance;GO:0016477:cell migration;GO:0021885:forebrain cell migration;GO:0001779:natural killer cell differentiation;GO:0050728:negative regulation of inflammatory response;GO:0045824:negative regulation of innate immune response;GO:0051250:negative regulation of lymphocyte activation;GO:0043524:negative regulation of neuron apoptotic process;GO:0034122:negative regulation of toll-like receptor signaling pathway;GO:0007399:nervous system development;GO:0070050:neuron cellular homeostasis;GO:0007218:neuropeptide signaling pathway;GO:0042698:ovulation cycle;GO:0006909:phagocytosis;GO:0030168:platelet activation;GO:0070527:platelet aggregation;GO:0033674:positive regulation of kinase activity;GO:1903902:positive regulation of viral life cycle;GO:0046777:protein autophosphorylation;GO:0043491:protein kinase B signaling;GO:0006468:protein phosphorylation;GO:0032940:secretion by cell;GO:0007283:spermatogenesis;GO:0034446:substrate adhesion-dependent cell spreading;GO:0007169:transmembrane receptor protein tyrosine kinase signaling pathway;GO:0060068:vagina development;	GO:0009986:cell surface;GO:0005789:endoplasmic reticulum membrane;GO:0005887:integral component of plasma membrane;GO:0005635:nuclear envelope;GO:0005634:nucleus;GO:0043235:receptor complex;	GO:0005524:ATP binding;GO:0043548:phosphatidylinositol 3-kinase binding;GO:0004713:protein tyrosine kinase activity;GO:0004714:transmembrane receptor protein tyrosine kinase activity;GO:0001618:virus receptor activity;	K05116	-
ENSMUSG00000024799	4403	259	3.05	253	3.27	126	1.32	73	0.99	173.561539289627	0.398976381697043	-1.32562474948504	0.265340534308757	-4.99593758992928	5.85505951496322e-07	1.79204556092706e-05	Down	19	6112851	6118403	-	Tm7sf2	transmembrane 7 superfamily member 2 [Source:MGI Symbol%3BAcc:MGI:1920416]	GO:0006695:cholesterol biosynthetic process;GO:0016126:sterol biosynthetic process;GO:0032456:endocytic recycling;GO:0007030:Golgi organization;GO:0048193:Golgi vesicle transport;GO:0006869:lipid transport;GO:0007041:lysosomal transport;GO:0015031:protein transport;GO:0042147:retrograde transport, endosome to Golgi;	GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0030176:integral component of endoplasmic reticulum membrane;GO:0043231:intracellular membrane-bounded organelle;GO:0005637:nuclear inner membrane;GO:0031090:organelle membrane;GO:0043235:receptor complex;GO:0005829:cytosol;GO:1990745:EARP complex;GO:0000938:GARP complex;GO:0005794:Golgi apparatus;GO:0016020:membrane;GO:0055037:recycling endosome;	GO:0050613:delta14-sterol reductase activity;GO:0050661:NADP binding;GO:0016627:oxidoreductase activity, acting on the CH-CH group of donors;	K00222	;ko00100 Steroid biosynthesis;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;
ENSMUSG00000028100	2239	18	0.42	4	0.10	87	1.79	64	1.70	43.1004576103583	7.16497826541299	2.84096232815407	0.570022869693266	4.98394446819795	6.23009666413366e-07	1.90303390931923e-05	Ups	3	96613383	96615878	-	Nudt17	nudix (nucleoside diphosphate linked moiety X)-type motif 17 [Source:MGI Symbol%3BAcc:MGI:1925623]	GO:0019677:NAD catabolic process;GO:0006734:NADH metabolic process;GO:0006742:NADP catabolic process;	GO:0005829:cytosol;GO:0005777:peroxisome;	GO:0046872:metal ion binding;GO:0035529:NADH pyrophosphatase activity;	-	-
ENSMUSG00000001942	10497	394	1.95	363	1.97	204	0.89	155	0.88	273.668212349421	0.491649706691101	-1.0242973126765	0.205783859845974	-4.97753960608557	6.43976077504407e-07	1.96316683348958e-05	Down	9	37466994	37560951	+	Siae	sialic acid acetylesterase [Source:MGI Symbol%3BAcc:MGI:104803]	GO:0005975:carbohydrate metabolic process;GO:0002682:regulation of immune system process;	GO:0005764:lysosome;	GO:0001681:sialate O-acetylesterase activity;	K05970	-
ENSMUSG00000004328	6710	130	1.01	191	1.62	56	0.38	37	0.33	101.527310676336	0.297374794161666	-1.74964572684829	0.352019231903937	-4.97031289280738	6.68449409493692e-07	2.0216968925397e-05	Down	7	16765432	16796352	-	Hif3a	hypoxia inducible factor 3%2C alpha subunit [Source:MGI Symbol%3BAcc:MGI:1859778]	GO:0001525:angiogenesis;GO:0006915:apoptotic process;GO:0071456:cellular response to hypoxia;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0001666:response to hypoxia;GO:0006366:transcription from RNA polymerase II promoter;	GO:0000785:chromatin;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005739:mitochondrion;GO:0016607:nuclear speck;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0005886:plasma membrane;	GO:0003677:DNA binding;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046983:protein dimerization activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000977:RNA polymerase II regulatory region sequence-specific DNA binding;	K09096	-
ENSMUSG00000104814	2228	113	2.63	116	2.96	249	5.14	290	7.75	193.768116756502	2.48065547399446	1.31072138034353	0.264530456553623	4.95489781184359	7.23683121950857e-07	2.17587391999891e-05	Ups	5	129633211	129635438	+	Gm42979	predicted gene 42979 [Source:MGI Symbol%3BAcc:MGI:5663116]	-	-	-	-	-
ENSMUSG00000062661	4653	72	0.80	64	0.78	199	1.97	150	1.92	120.55384875188	2.65929763555013	1.41104525643651	0.285138849803762	4.94862505550407	7.47395637310021e-07	2.22968184873772e-05	Ups	2	31135835	31186001	+	Ncs1	neuronal calcium sensor 1 [Source:MGI Symbol%3BAcc:MGI:109166]	GO:0048015:phosphatidylinositol-mediated signaling;GO:0045921:positive regulation of exocytosis;GO:0010975:regulation of neuron projection development;GO:2000300:regulation of synaptic vesicle exocytosis;	GO:0044305:calyx of Held;GO:0005737:cytoplasm;GO:0030425:dendrite;GO:0031045:dense core granule;GO:0005794:Golgi apparatus;GO:0043231:intracellular membrane-bounded organelle;GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;GO:0014069:postsynaptic density;	GO:0005509:calcium ion binding;GO:0000287:magnesium ion binding;GO:0019901:protein kinase binding;GO:0005245:voltage-gated calcium channel activity;	-	-
ENSMUSG00000028496	12004	623	2.69	693	3.29	249	0.95	317	1.57	465.597575491877	0.454277553000041	-1.13835407493317	0.230388994786416	-4.94100890534503	7.7719358174676e-07	2.30108585019197e-05	Down	4	87688162	87951601	-	Mllt3	myeloid/lymphoid or mixed-lineage leukemia%3B translocated to%2C 3 [Source:MGI Symbol%3BAcc:MGI:1917372]	GO:0009952:anterior/posterior pattern specification;GO:0010467:gene expression;GO:0060218:hematopoietic stem cell differentiation;GO:0090090:negative regulation of canonical Wnt signaling pathway;GO:0045893:positive regulation of transcription, DNA-templated;GO:2000096:positive regulation of Wnt signaling pathway, planar cell polarity pathway;GO:1902275:regulation of chromatin organization;GO:2000035:regulation of stem cell division;GO:0007379:segment specification;	GO:0005694:chromosome;GO:0005829:cytosol;GO:0005654:nucleoplasm;GO:0008023:transcription elongation factor complex;	GO:0003682:chromatin binding;GO:0003677:DNA binding;GO:0042393:histone binding;GO:0070577:lysine-acetylated histone binding;	K15187	;ko05202 Transcriptional misregulation in cancer;
ENSMUSG00000024411	6233	12	0.10	5	0.05	62	0.46	57	0.54	34.2358193551899	7.3443363976384	2.87663214100796	0.582243725890001	4.94059791990171	7.78833674350876e-07	2.30108585019197e-05	Ups	18	15522553	15544039	-	Aqp4	aquaporin 4 [Source:MGI Symbol%3BAcc:MGI:107387]	GO:0015670:carbon dioxide transport;GO:0098609:cell-cell adhesion;GO:0071333:cellular response to glucose stimulus;GO:0071346:cellular response to interferon-gamma;GO:0009992:cellular water homeostasis;GO:0033326:cerebrospinal fluid secretion;GO:0060354:negative regulation of cell adhesion molecule production;GO:0032691:negative regulation of interleukin-1 beta production;GO:0032715:negative regulation of interleukin-6 production;GO:0051289:protein homotetramerization;GO:0010574:regulation of vascular endothelial growth factor production;GO:0070295:renal water absorption;GO:0007605:sensory perception of sound;GO:0030104:water homeostasis;GO:0006833:water transport;	GO:0097450:astrocyte end-foot;GO:0009925:basal plasma membrane;GO:0016323:basolateral plasma membrane;GO:0031253:cell projection membrane;GO:0005911:cell-cell junction;GO:0005737:cytoplasm;GO:0010008:endosome membrane;GO:0009897:external side of plasma membrane;GO:0005576:extracellular region;GO:0016021:integral component of membrane;GO:0005887:integral component of plasma membrane;GO:0005886:plasma membrane;GO:0032991:macromolecular complex;GO:0042383:sarcolemma;GO:0030315:T-tubule;	GO:0042802:identical protein binding;GO:0015250:water channel activity;	K09866	;ko04962 Vasopressin-regulated water reabsorption;ko04976 Bile secretion;
ENSMUSG00000026883	8366	49	0.30	41	0.28	193	1.06	103	0.73	94.8917735074771	3.36215715821104	1.74938716243028	0.354140623046748	4.93980935420492	7.81989891691996e-07	2.30596788446251e-05	Ups	2	35448278	35621006	+	Dab2ip	disabled 2 interacting protein [Source:MGI Symbol%3BAcc:MGI:1916851]	GO:0007257:activation of JUN kinase activity;GO:0000185:activation of MAPKKK activity;GO:0001525:angiogenesis;GO:0007049:cell cycle;	GO:1990597:AIP1-IRE1 complex;GO:0030424:axon;GO:0044300:cerebellar mossy fiber;GO:0044301:climbing fiber;	GO:0071889:14-3-3 protein binding;GO:0005123:death receptor binding;GO:0005096:GTPase activator activity;GO:0042802:identical protein binding;	K17633;K17631	;ko04014 Ras signaling pathway;;ko04014 Ras signaling pathway;
ENSMUSG00000048621	2795	717	13.32	573	11.67	285	4.69	316	6.73	465.813013986009	0.491256869502758	-1.02545051341277	0.207897093503958	-4.93249085944171	8.11875800261637e-07	2.38950163554932e-05	Down	X	108240362	108244045	+	Gm6377	predicted gene 6377 [Source:MGI Symbol%3BAcc:MGI:3647255]	-	-	-	-	-
ENSMUSG00000026603	2717	299	5.71	166	3.48	587	9.94	460	10.08	375.241697294321	2.34981638021236	1.23254802585113	0.250055206624243	4.92910362671743	8.26077517739301e-07	2.42200242007924e-05	Ups	1	189612689	189654560	-	Smyd2	SET and MYND domain containing 2 [Source:MGI Symbol%3BAcc:MGI:1915889]	GO:0007507:heart development;GO:0034968:histone lysine methylation;GO:0016571:histone methylation;GO:0008285:negative regulation of cell proliferation;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0018027:peptidyl-lysine dimethylation;GO:0018026:peptidyl-lysine monomethylation;GO:0043516:regulation of DNA damage response, signal transduction by p53 class mediator;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005634:nucleus;	GO:0046975:histone methyltransferase activity (H3-K36 specific);GO:0018024:histone-lysine N-methyltransferase activity;GO:0046872:metal ion binding;GO:0002039:p53 binding;GO:0016279:protein-lysine N-methyltransferase activity;GO:0000993:RNA polymerase II core binding;	K11426	;ko00310 Lysine degradation;ko01100 Metabolic pathways;
ENSMUSG00000063820	597	12	1.04	8	0.76	57	4.39	68	6.78	36.905709802216	6.6107889303954	2.72482245298121	0.552956229275496	4.92773624514796	8.31878093229771e-07	2.4343547102262e-05	Ups	5	77151902	77158453	+	Arl9	ADP-ribosylation factor-like 9 [Source:MGI Symbol%3BAcc:MGI:1915496]	-	-	GO:0005525:GTP binding;GO:0003924:GTPase activity;	K07957	-
ENSMUSG00000105814	109	101	48.10	84	43.85	286	120.74	175	95.62	159.356660170216	2.56177422415989	1.35714333280759	0.275572865255901	4.92480756966884	8.44434114511816e-07	2.45703087512793e-05	Ups	5	98623415	98623523	-	Mir703	microRNA 703 [Source:MGI Symbol%3BAcc:MGI:3629657]	-	-	-	-	-
ENSMUSG00000038712	6458	199	1.60	268	2.36	103	0.73	57	0.53	153.402305698791	0.349605788382207	-1.51619902331781	0.308222219830217	-4.91917495160798	8.6909763570336e-07	2.52400438368851e-05	Down	3	95188656	95203477	+	Mindy1	MINDY lysine 48 deubiquitinase 1 [Source:MGI Symbol%3BAcc:MGI:1922257]	GO:0071108:protein K48-linked deubiquitination;	GO:0071944:cell periphery;GO:0005829:cytosol;GO:0016604:nuclear body;GO:0005654:nucleoplasm;	GO:0016807:cysteine-type carboxypeptidase activity;GO:0036435:K48-linked polyubiquitin binding;GO:1990380:Lys48-specific deubiquitinase activity;GO:0004843:ubiquitin-specific protease activity;	K01514	;ko00230 Purine metabolism;ko01100 Metabolic pathways;
ENSMUSG00000036278	1228	135	5.71	105	4.87	38	1.42	29	1.41	74.8734468817543	0.290196129094924	-1.78489981935866	0.363177448322257	-4.91467690960499	8.89289921318034e-07	2.57776401767311e-05	Down	19	7034178	7175422	+	Macrod1	mono-ADP ribosylhydrolase 1 [Source:MGI Symbol%3BAcc:MGI:2147583]	GO:0006974:cellular response to DNA damage stimulus;GO:0051725:protein de-ADP-ribosylation;GO:0042278:purine nucleoside metabolic process;	GO:0005739:mitochondrion;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0019213:deacetylase activity;GO:0016798:hydrolase activity, acting on glycosyl bonds;	-	-
ENSMUSG00000112301	1779	32	0.93	32	1.02	119	3.08	96	3.21	69.6761493269334	3.48717666020996	1.80205945283069	0.36677023084524	4.91331984244674	8.95470159624222e-07	2.58590196378113e-05	Ups	10	115151551	115153329	+	Gm10752	predicted gene 10752 [Source:MGI Symbol%3BAcc:MGI:3642645]	-	-	-	-	-
ENSMUSG00000021476	5362	307	2.97	221	2.35	116	1.00	94	1.04	180.459430602359	0.414530682221934	-1.27044920558803	0.258878828592929	-4.90750523128229	9.22421958370654e-07	2.65872524617587e-05	Down	13	64309638	64334351	+	Habp4	hyaluronic acid binding protein 4 [Source:MGI Symbol%3BAcc:MGI:1891713]	GO:0071260:cellular response to mechanical stimulus;GO:0030212:hyaluronan metabolic process;GO:0006397:mRNA processing;GO:0043392:negative regulation of DNA binding;GO:0030578:PML body organization;GO:0033120:positive regulation of RNA splicing;GO:0045948:positive regulation of translational initiation;GO:0008380:RNA splicing;	GO:0015030:Cajal body;GO:0005737:cytoplasm;GO:0010494:cytoplasmic stress granule;GO:0005829:cytosol;GO:0097504:Gemini of coiled bodies;GO:0005794:Golgi apparatus;GO:0016607:nuclear speck;GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0030017:sarcomere;GO:0016528:sarcoplasm;	GO:0005540:hyaluronic acid binding;GO:0003723:RNA binding;GO:0032183:SUMO binding;	K19019	-
ENSMUSG00000087281	390	187	24.89	208	30.35	39	4.60	70	10.69	124.517855681391	0.29409705441683	-1.7656357601677	0.36049228817583	-4.897846134524	9.68928569139414e-07	2.77711227648295e-05	Down	5	44066557	44067227	-	Gm16015	predicted gene 16015 [Source:MGI Symbol%3BAcc:MGI:3801811]	-	-	-	-	-
ENSMUSG00000075289	4525	169	1.94	175	2.20	67	0.68	56	0.74	114.563549156501	0.371410466480087	-1.42891362337775	0.291933518068854	-4.89465421041763	9.84787296726748e-07	2.81205370726405e-05	Down	19	4214323	4225478	-	Carns1	carnosine synthase 1 [Source:MGI Symbol%3BAcc:MGI:2147595]	GO:0035499:carnosine biosynthetic process;	-	GO:0005524:ATP binding;GO:0047730:carnosine synthase activity;GO:0046872:metal ion binding;	K14755	;ko00330 Arginine and proline metabolism;ko00340 Histidine metabolism;ko00410 beta-Alanine metabolism;ko01100 Metabolic pathways;
ENSMUSG00000121042	3354	135	2.09	180	3.05	52	0.71	47	0.83	101.833106808432	0.326278885210571	-1.61582246690485	0.332188728869283	-4.86417005298419	1.14938065015925e-06	3.23387208982421e-05	Down	1	182082891	182093596	+	-	novel transcript	-	-	-	-	-
ENSMUSG00000061186	9128	26	0.15	21	0.13	84	0.42	103	0.67	59.4260140167077	4.20921244409893	2.07355032609934	0.426852027936944	4.85777316350398	1.18713297855201e-06	3.32771981114498e-05	Ups	2	10375321	10600064	+	Sfmbt2	Scm-like with four mbt domains 2 [Source:MGI Symbol%3BAcc:MGI:2447794]	GO:0010629:negative regulation of gene expression;GO:0045892:negative regulation of transcription, DNA-templated;	GO:0016235:aggresome;GO:0005829:cytosol;GO:0043231:intracellular membrane-bounded organelle;GO:0016604:nuclear body;GO:0016607:nuclear speck;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0003682:chromatin binding;GO:0042393:histone binding;GO:0003714:transcription corepressor activity;	-	-
ENSMUSG00000026357	2031	131	3.35	166	4.65	55	1.25	38	1.11	95.5730330396162	0.322545646790018	-1.63242474911891	0.336841243229597	-4.84627337634607	1.25802139451144e-06	3.48833635866879e-05	Down	1	144628421	144651173	-	Rgs18	regulator of G-protein signaling 18 [Source:MGI Symbol%3BAcc:MGI:1927498]	GO:0007186:G-protein coupled receptor signaling pathway;GO:0009968:negative regulation of signal transduction;GO:0008277:regulation of G-protein coupled receptor protein signaling pathway;	GO:0005737:cytoplasm;	GO:0005096:GTPase activator activity;	K16449	-
ENSMUSG00000041594	8280	415	2.60	324	2.23	174	0.97	162	1.17	263.947123044145	0.475848679391685	-1.07142522765435	0.22176330566406	-4.8313909483177	1.35582475034518e-06	3.71918009334401e-05	Down	14	123156383	123221447	-	Tmtc4	transmembrane and tetratricopeptide repeat containing 4 [Source:MGI Symbol%3BAcc:MGI:1921050]	GO:0030968:endoplasmic reticulum unfolded protein response;GO:0032470:positive regulation of endoplasmic reticulum calcium ion concentration;GO:0035269:protein O-linked mannosylation;GO:0007605:sensory perception of sound;	GO:0005783:endoplasmic reticulum;GO:0016021:integral component of membrane;	GO:0051117:ATPase binding;GO:0004169:dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0000030:mannosyltransferase activity;	-	-
ENSMUSG00000022074	5451	201	1.91	196	2.05	482	4.07	314	3.43	294.734579675782	2.06280864896052	1.0446099996057	0.216261342669712	4.83031311426333	1.36318510511976e-06	3.73269292891186e-05	Ups	14	70004921	70021860	+	Tnfrsf10b	tumor necrosis factor receptor superfamily%2C member 10b [Source:MGI Symbol%3BAcc:MGI:1341090]	GO:0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0097191:extrinsic apoptotic signaling pathway;GO:0008625:extrinsic apoptotic signaling pathway via death domain receptors;GO:0070059:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0043065:positive regulation of apoptotic process;GO:0034976:response to endoplasmic reticulum stress;GO:0036462:TRAIL-activated apoptotic signaling pathway;	GO:0009986:cell surface;GO:0005829:cytosol;GO:0005794:Golgi apparatus;GO:0016021:integral component of membrane;GO:0016020:membrane;GO:0045121:membrane raft;GO:0005886:plasma membrane;	GO:0042802:identical protein binding;GO:0002020:protease binding;GO:0045569:TRAIL binding;	K04722	;ko04060 Cytokine-cytokine receptor interaction;ko04061 Viral protein interaction with cytokine and cytokine receptor;ko04115 p53 signaling pathway;ko04210 Apoptosis;ko04217 Necroptosis;ko04650 Natural killer cell mediated cytotoxicity;ko05130 Pathogenic Escherichia coli infection;ko05132 Salmonella infection;ko05164 Influenza A;
ENSMUSG00000055897	12855	637	2.57	647	2.86	280	1.00	326	1.51	467.055185009268	0.49712032937537	-1.00833299243298	0.208855880956418	-4.82788891466927	1.37988024701086e-06	3.77167267516302e-05	Down	2	173421113	173501448	-	Ppp4r1l-ps	protein phosphatase 4%2C regulatory subunit 1-like%2C pseudogene [Source:MGI Symbol%3BAcc:MGI:1924560]	GO:0006470:protein dephosphorylation;GO:0006468:protein phosphorylation;GO:0007165:signal transduction;	GO:0030289:protein phosphatase 4 complex;	GO:0019888:protein phosphatase regulator activity;	K15424	-
ENSMUSG00000031700	5643	294	2.70	392	3.95	136	1.11	142	1.50	238.064560867928	0.423208017163907	-1.24056113706431	0.25822988488744	-4.80409592253453	1.55452295852011e-06	4.20406614566973e-05	Down	8	86219205	86254189	+	Gpt2	glutamic pyruvate transaminase (alanine aminotransferase) 2 [Source:MGI Symbol%3BAcc:MGI:1915391]	GO:0006103:2-oxoglutarate metabolic process;GO:0009058:biosynthetic process;GO:0042853:L-alanine catabolic process;GO:0042851:L-alanine metabolic process;GO:0045722:positive regulation of gluconeogenesis;	GO:0005615:extracellular space;GO:0005739:mitochondrion;	GO:0004021:L-alanine:2-oxoglutarate aminotransferase activity;GO:0030170:pyridoxal phosphate binding;	K00814	;ko00220 Arginine biosynthesis;ko00250 Alanine, aspartate and glutamate metabolism;ko00710 Carbon fixation in photosynthetic organisms;ko01100 Metabolic pathways;ko01120 Microbial metabolism in diverse environments;ko01200 Carbon metabolism;ko01210 2-Oxocarboxylic acid metabolism;ko01230 Biosynthesis of amino acids;
ENSMUSG00000029638	7756	288	1.93	312	2.29	61	0.36	118	0.91	192.748683348683	0.319814724911867	-1.64469172996445	0.342836665853349	-4.79730406276899	1.60815390021638e-06	4.33381931562706e-05	Down	6	8509600	8597548	+	Glcci1	glucocorticoid induced transcript 1 [Source:MGI Symbol%3BAcc:MGI:2179717]	-	GO:0005737:cytoplasm;	-	K10292	;ko04114 Oocyte meiosis;
ENSMUSG00000031286	2732	20	0.38	12	0.25	97	1.63	58	1.26	46.1922457215143	4.98673675563401	2.31809604672364	0.484144836752816	4.788021828904	1.68433331312432e-06	4.51530892018327e-05	Ups	3	85777156	85794823	-	Glt28d2	glycosyltransferase 28 domain containing 2 [Source:MGI Symbol%3BAcc:MGI:2443773]	GO:0006488:dolichol-linked oligosaccharide biosynthetic process;GO:1901215:negative regulation of neuron death;GO:1904262:negative regulation of TORC1 signaling;GO:0048167:regulation of synaptic plasticity;	GO:0005737:cytoplasm;GO:0005783:endoplasmic reticulum;	GO:0004577:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity;	K07432	;ko00510 N-Glycan biosynthesis;ko00513 Various types of N-glycan biosynthesis;ko01100 Metabolic pathways;
ENSMUSG00000001436	4644	685	7.66	390	4.78	1348	13.36	908	11.64	822.116415541332	2.17512219096525	1.12109644893745	0.234222046163251	4.7864685126867	1.69741555052663e-06	4.54243805441105e-05	Ups	10	76868075	76896836	+	Slc19a1	solute carrier family 19 (folate transporter)%2C member 1 [Source:MGI Symbol%3BAcc:MGI:103182]	GO:0051503:adenine nucleotide transport;GO:0007565:female pregnancy;GO:0015884:folic acid transport;GO:1903790:guanine nucleotide transmembrane transport;GO:0051958:methotrexate transport;GO:0015711:organic anion transport;GO:0055085:transmembrane transport;	GO:0016324:apical plasma membrane;GO:0016323:basolateral plasma membrane;GO:0031526:brush border membrane;GO:0005887:integral component of plasma membrane;GO:0005886:plasma membrane;	GO:0061507:cyclic-GMP-AMP binding;GO:0008518:reduced folate carrier activity;GO:0005542:folic acid binding;GO:0008517:folic acid transporter activity;GO:0015350:methotrexate transporter activity;GO:0008514:organic anion transmembrane transporter activity;	K14609	;ko01523 Antifolate resistance;ko04977 Vitamin digestion and absorption;
ENSMUSG00000024236	10701	628	3.05	525	2.79	244	1.05	287	1.60	415.325486910696	0.486459821080676	-1.0396074436763	0.217804976457704	-4.7731115265779	1.81401270092048e-06	4.7711956699682e-05	Down	18	4920540	5119299	+	Svil	supervillin [Source:MGI Symbol%3BAcc:MGI:2147319]	GO:0051014:actin filament severing;GO:0008154:actin polymerization or depolymerization;GO:0051016:barbed-end actin filament capping;GO:0032467:positive regulation of cytokinesis;GO:0007519:skeletal muscle tissue development;	GO:0015629:actin cytoskeleton;GO:0030054:cell junction;GO:0042995:cell projection;GO:0032154:cleavage furrow;GO:0043034:costamere;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0036449:microtubule minus-end;GO:0030496:midbody;GO:0005634:nucleus;GO:0005886:plasma membrane;GO:0002102:podosome;	GO:0051015:actin filament binding;GO:0005546:phosphatidylinositol-4,5-bisphosphate binding;	K10369	-
ENSMUSG00000020027	9531	185	1.01	146	0.87	429	2.07	272	1.70	254.57931575233	2.18136290266014	1.1252298040524	0.236317829425098	4.76151040651397	1.9214938814413e-06	5.01945267087238e-05	Ups	10	95221224	95253042	-	Socs2	suppressor of cytokine signaling 2 [Source:MGI Symbol%3BAcc:MGI:1201787]	GO:0032870:cellular response to hormone stimulus;GO:0060396:growth hormone receptor signaling pathway;GO:0035556:intracellular signal transduction;GO:0007595:lactation;GO:0060749:mammary gland alveolus development;GO:0040015:negative regulation of multicellular organism growth;GO:0046426:negative regulation of JAK-STAT cascade;GO:0046854:phosphatidylinositol phosphorylation;GO:0045666:positive regulation of neuron differentiation;GO:0016567:protein ubiquitination;GO:0001558:regulation of cell growth;GO:0040014:regulation of multicellular organism growth;GO:0032355:response to estradiol;	GO:0005737:cytoplasm;GO:0005942:phosphatidylinositol 3-kinase complex;	GO:0046935:1-phosphatidylinositol-3-kinase regulator activity;GO:0005131:growth hormone receptor binding;GO:0005159:insulin-like growth factor receptor binding;GO:0008269:JAK pathway signal transduction adaptor activity;	K04695	;ko04630 JAK-STAT signaling pathway;ko04910 Insulin signaling pathway;ko04917 Prolactin signaling pathway;ko04930 Type II diabetes mellitus;ko04935 Growth hormone synthesis, secretion and action;
ENSMUSG00000041912	6142	36	0.30	45	0.42	114	0.85	151	1.46	88.0661134957368	3.45994719177949	1.7907500185732	0.376502821757554	4.75627250338735	1.9720023624314e-06	5.13390224541989e-05	Ups	3	94320580	94341975	+	Tdrkh	tudor and KH domain containing protein [Source:MGI Symbol%3BAcc:MGI:1919884]	GO:0030154:cell differentiation;GO:0043046:DNA methylation involved in gamete generation;GO:0009566:fertilization;GO:0031047:gene silencing by RNA;GO:0007140:male meiosis;GO:0034587:piRNA metabolic process;GO:0007283:spermatogenesis;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005739:mitochondrion;GO:0071546:pi-body;GO:0071547:piP-body;	GO:0003723:RNA binding;	K18406	-
ENSMUSG00000044471	8616	16	0.10	20	0.13	65	0.35	107	0.74	53.5678794647074	5.09974334838563	2.35042464329427	0.496009444417073	4.73866913170689	2.15126431471388e-06	5.56281399693466e-05	Ups	6	31059500	31197423	-	Lncpint	long non-protein coding RNA%2C Trp53 induced transcript [Source:MGI Symbol%3BAcc:MGI:2673128]	-	-	-	-	-
ENSMUSG00000018909	11175	408	1.90	398	2.03	182	0.75	195	1.04	291.813992263925	0.49083559260625	-1.02668822605218	0.217200709996705	-4.72691008269609	2.27962149291578e-06	5.84543745357366e-05	Down	7	99184673	99255978	+	Arrb1	arrestin%2C beta 1 [Source:MGI Symbol%3BAcc:MGI:99473]	GO:0000187:activation of MAPK activity;GO:0006897:endocytosis;GO:0042699:follicle-stimulating hormone signaling pathway;GO:0002031:G-protein coupled receptor internalization;GO:0007188:adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0045746:negative regulation of Notch signaling pathway;GO:0001934:positive regulation of protein phosphorylation;GO:0002092:positive regulation of receptor internalization;GO:0015031:protein transport;GO:0007165:signal transduction;GO:0006511:ubiquitin-dependent protein catabolic process;	GO:0016323:basolateral plasma membrane;GO:0000785:chromatin;GO:0005905:coated pit;GO:0005737:cytoplasm;GO:0031410:cytoplasmic vesicle;GO:0005634:nucleus;GO:0031143:pseudopodium;	GO:0031691:alpha-1A adrenergic receptor binding;GO:0031692:alpha-1B adrenergic receptor binding;GO:0031701:angiotensin receptor binding;GO:0035612:AP-2 adaptor complex binding;	K04439	;ko04010 MAPK signaling pathway;ko04062 Chemokine signaling pathway;ko04144 Endocytosis;ko04340 Hedgehog signaling pathway;ko04728 Dopaminergic synapse;ko04740 Olfactory transduction;ko04926 Relaxin signaling pathway;ko04928 Parathyroid hormone synthesis, secretion and action;ko04929 GnRH secretion;ko05032 Morphine addiction;
ENSMUSG00000045763	2009	640	16.54	822	23.28	1987	45.51	1063	31.51	1109.43216179888	2.11716193933964	1.08213162368985	0.229120428819054	4.72298183652781	2.32411613656839e-06	5.94958210987308e-05	Ups	15	25363363	25413850	-	Basp1	brain abundant%2C membrane attached signal protein 1 [Source:MGI Symbol%3BAcc:MGI:1917600]	-	-	-	K17272	-
ENSMUSG00000039063	2685	55	1.06	70	1.48	12	0.21	8	0.18	35.4332060438601	0.164940041330929	-2.59998642068992	0.550699804553738	-4.72124086333539	2.3441014636302e-06	5.97083917662881e-05	Down	2	6193276	6217844	-	Echdc3	enoyl Coenzyme A hydratase domain containing 3 [Source:MGI Symbol%3BAcc:MGI:1915106]	GO:0006631:fatty acid metabolic process;GO:1900078:positive regulation of cellular response to insulin stimulus;	GO:0005739:mitochondrion;	GO:0004300:enoyl-CoA hydratase activity;	-	-
ENSMUSG00000033307	745	1333	92.89	1366	104.34	3553	219.45	1813	144.93	1977.86984184813	2.01904851993961	1.01367558062242	0.215022618966188	4.7142741796007	2.42573853766601e-06	6.12788710651905e-05	Ups	10	75695187	75696074	-	Mif	macrophage migration inhibitory factor (glycosylation-inhibiting factor) [Source:MGI Symbol%3BAcc:MGI:96982]	GO:0002035:brain renin-angiotensin system;GO:0019752:carboxylic acid metabolic process;GO:0007569:cell aging;GO:0007166:cell surface receptor signaling pathway;GO:0030330:DNA damage response, signal transduction by p53 class mediator;GO:0042756:drinking behavior;GO:0006954:inflammatory response;GO:0045087:innate immune response;GO:0043066:negative regulation of apoptotic process;GO:0090344:negative regulation of cell aging;GO:0030336:negative regulation of cell migration;GO:0032269:negative regulation of cellular protein metabolic process;GO:0043518:negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0010629:negative regulation of gene expression;GO:1902166:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0010760:negative regulation of macrophage chemotaxis;GO:0002906:negative regulation of mature B cell apoptotic process;GO:0033033:negative regulation of myeloid cell apoptotic process;GO:0002675:positive regulation of acute inflammatory response;GO:0002821:positive regulation of adaptive immune response;GO:0090238:positive regulation of arachidonic acid secretion;GO:0048680:positive regulation of axon regeneration;GO:0030890:positive regulation of B cell proliferation;GO:2000343:positive regulation of chemokine (C-X-C motif) ligand 2 production;GO:0001819:positive regulation of cytokine production;GO:0070374:positive regulation of ERK1 and ERK2 cascade;GO:0048146:positive regulation of fibroblast proliferation;GO:0046326:positive regulation of glucose import;GO:0045821:positive regulation of glycolytic process;GO:0050778:positive regulation of immune response;GO:0031666:positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0043406:positive regulation of MAP kinase activity;GO:0061081:positive regulation of myeloid leukocyte cytokine production involved in immune response;GO:0033138:positive regulation of peptidyl-serine phosphorylation;GO:0050731:positive regulation of peptidyl-tyrosine phosphorylation;GO:0042327:positive regulation of phosphorylation;GO:0043268:positive regulation of potassium ion transport;GO:0061078:positive regulation of prostaglandin secretion involved in immune response;GO:0010739:positive regulation of protein kinase A signaling;GO:0001934:positive regulation of protein phosphorylation;GO:0014911:positive regulation of smooth muscle cell migration;GO:0032760:positive regulation of tumor necrosis factor production;GO:0001516:prostaglandin biosynthetic process;GO:0070207:protein homotrimerization;GO:0051726:regulation of cell cycle;GO:0042127:regulation of cell proliferation;GO:0007283:spermatogenesis;	GO:0009986:cell surface;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005576:extracellular region;GO:0005615:extracellular space;GO:0043209:myelin sheath;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0005886:plasma membrane;	GO:0042056:chemoattractant activity;GO:0005125:cytokine activity;GO:0005126:cytokine receptor binding;GO:0004167:dopachrome isomerase activity;GO:0042802:identical protein binding;GO:0050178:phenylpyruvate tautomerase activity;GO:0002020:protease binding;GO:0044877:macromolecular complex binding;	K07253	;ko00350 Tyrosine metabolism;ko00360 Phenylalanine metabolism;ko01100 Metabolic pathways;
ENSMUSG00000032740	11385	1312	5.98	1317	6.58	497	2.01	686	3.59	943.82485290183	0.478262124546561	-1.06412655171802	0.226482639474699	-4.69849059595092	2.62091255007745e-06	6.52574178962198e-05	Down	11	29323658	29460808	+	Ccdc88a	coiled coil domain containing 88A [Source:MGI Symbol%3BAcc:MGI:1925177]	GO:0032147:activation of protein kinase activity;GO:0032148:activation of protein kinase B activity;GO:0016477:cell migration;GO:0031122:cytoplasmic microtubule organization;GO:0030705:cytoskeleton-dependent intracellular transport;GO:0006260:DNA replication;GO:0030032:lamellipodium assembly;GO:0072660:maintenance of protein location in plasma membrane;GO:0061024:membrane organization;GO:0007399:nervous system development;GO:0045724:positive regulation of cilium assembly;GO:0045742:positive regulation of epidermal growth factor receptor signaling pathway;GO:1903566:positive regulation of protein localization to cilium;GO:0051496:positive regulation of stress fiber assembly;GO:0032956:regulation of actin cytoskeleton organization;GO:0042127:regulation of cell proliferation;GO:0006275:regulation of DNA replication;GO:0010975:regulation of neuron projection development;GO:0001932:regulation of protein phosphorylation;GO:0007264:small GTPase mediated signal transduction;GO:0031929:TOR signaling;	GO:0031252:cell leading edge;GO:0005814:centriole;GO:0005813:centrosome;GO:0036064:ciliary basal body;GO:0030142:Golgi to ER transport vesicle;GO:0005737:cytoplasm;GO:0031410:cytoplasmic vesicle;GO:0005829:cytosol;GO:0005783:endoplasmic reticulum;GO:0005794:Golgi apparatus;GO:0030027:lamellipodium;GO:0016020:membrane;GO:0005886:plasma membrane;	GO:0003779:actin binding;GO:0051959:dynein light intermediate chain binding;GO:0005154:epidermal growth factor receptor binding;GO:0001965:G-protein alpha-subunit binding;GO:0031682:G-protein gamma-subunit binding;GO:0005092:GDP-dissociation inhibitor activity;GO:0005085:guanyl-nucleotide exchange factor activity;GO:0005158:insulin receptor binding;GO:0008017:microtubule binding;GO:0035091:phosphatidylinositol binding;GO:0042803:protein homodimerization activity;GO:0043422:protein kinase B binding;GO:0005080:protein kinase C binding;GO:0042169:SH2 domain binding;GO:0043184:vascular endothelial growth factor receptor 2 binding;	-	-
ENSMUSG00000039328	9012	195	1.12	248	1.57	100	0.51	72	0.48	150.964553184437	0.400230135001462	-1.32109829700804	0.281299954705829	-4.69640422939131	2.64781294569636e-06	6.58048034186516e-05	Down	8	31601848	31621510	+	Rnf122	ring finger protein 122 [Source:MGI Symbol%3BAcc:MGI:1916117]	GO:0010917:negative regulation of mitochondrial membrane potential;GO:0043065:positive regulation of apoptotic process;GO:0043161:proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051865:protein autoubiquitination;	GO:0005737:cytoplasm;GO:0012505:endomembrane system;GO:0005783:endoplasmic reticulum;GO:0005794:Golgi apparatus;GO:0016021:integral component of membrane;	GO:0046872:metal ion binding;GO:0061630:ubiquitin protein ligase activity;	K15699	-
ENSMUSG00000025932	7808	211	1.40	203	1.48	90	0.53	79	0.60	143.162948723223	0.425088349641802	-1.23416537518179	0.263006897282235	-4.69252094882288	2.69858891652447e-06	6.68500201066014e-05	Down	1	14239178	14380459	-	Eya1	EYA transcriptional coactivator and phosphatase 1 [Source:MGI Symbol%3BAcc:MGI:109344]	GO:0048856:anatomical structure development;GO:0009887:organ morphogenesis;GO:0035909:aorta morphogenesis;GO:0001658:branching involved in ureteric bud morphogenesis;GO:0030154:cell differentiation;GO:0045165:cell fate commitment;GO:0090103:cochlea morphogenesis;GO:0006302:double-strand break repair;GO:0048704:embryonic skeletal system morphogenesis;GO:0016576:histone dephosphorylation;GO:0042472:inner ear morphogenesis;GO:0007501:mesodermal cell fate specification;GO:0001656:metanephros development;GO:0042474:middle ear morphogenesis;GO:2001240:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0048665:neuron fate specification;GO:0071599:otic vesicle development;GO:0071600:otic vesicle morphogenesis;GO:0042473:outer ear morphogenesis;GO:0003151:outflow tract morphogenesis;GO:0007389:pattern specification process;GO:0060037:pharyngeal system development;GO:0045739:positive regulation of DNA repair;GO:0050679:positive regulation of epithelial cell proliferation;GO:0072513:positive regulation of secondary heart field cardioblast proliferation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-templated;GO:0006470:protein dephosphorylation;GO:0016925:protein sumoylation;GO:0045664:regulation of neuron differentiation;GO:0010212:response to ionizing radiation;GO:0048752:semicircular canal morphogenesis;GO:0014706:striated muscle tissue development;GO:0001657:ureteric bud development;	GO:0005737:cytoplasm;GO:0016604:nuclear body;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0032991:macromolecular complex;GO:0032993:protein-DNA complex;	GO:0046872:metal ion binding;GO:0004725:protein tyrosine phosphatase activity;GO:0003723:RNA binding;	K15616	;ko05202 Transcriptional misregulation in cancer;
ENSMUSG00000078771	2297	1408	31.82	1328	32.90	868	17.39	424	10.99	981.345715208194	0.479743297912258	-1.05966544299779	0.226075925208128	-4.687210467113	2.76954110471298e-06	6.84970053220465e-05	Down	11	79417386	79421435	-	Evi2a	ecotropic viral integration site 2a [Source:MGI Symbol%3BAcc:MGI:95458]	-	GO:0016021:integral component of membrane;	-	-	-
ENSMUSG00000020658	10382	112	0.56	87	0.48	33	0.15	16	0.09	60.1788334909295	0.252825963530334	-1.98378346866239	0.423684903194102	-4.68221419669882	2.83792708879433e-06	7.00112748687559e-05	Down	12	4012554	4088915	-	Efr3b	EFR3 homolog B [Source:MGI Symbol%3BAcc:MGI:2444851]	GO:0046854:phosphatidylinositol phosphorylation;GO:0072659:protein localization to plasma membrane;	GO:0015629:actin cytoskeleton;GO:0005829:cytosol;GO:0005886:plasma membrane;	-	K10899	-
ENSMUSG00000035413	1633	19	0.60	17	0.59	97	2.73	59	2.15	47.4833856894029	4.45174831453506	2.15437203031773	0.460132202873292	4.68207184123339	2.83989911101905e-06	7.00112748687559e-05	Ups	11	80701001	80712859	+	Tmem98	transmembrane protein 98 [Source:MGI Symbol%3BAcc:MGI:1923457]	GO:0031642:negative regulation of myelination;GO:0048715:negative regulation of oligodendrocyte differentiation;GO:1900181:negative regulation of protein localization to nucleus;GO:0010955:negative regulation of protein processing;GO:0045063:T-helper 1 cell differentiation;	GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0070062:extracellular exosome;GO:0005615:extracellular space;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	-	-	-
ENSMUSG00000086825	3681	219	3.09	345	5.33	110	1.38	99	1.60	190.668244262745	0.383983376540149	-1.38088423993627	0.295153050626212	-4.67853622724384	2.8893012706489e-06	7.10008744937983e-05	Down	1	130357518	130364928	-	Gm15675	predicted gene 15675 [Source:MGI Symbol%3BAcc:MGI:3783117]	-	-	-	-	-
ENSMUSG00000030730	3477	113	1.69	127	2.08	43	0.57	30	0.51	76.6034532748031	0.313966619684716	-1.67131691212474	0.35778777536394	-4.67125214220829	2.99369183858857e-06	7.28655089728843e-05	Down	7	126045030	126062280	-	Atp2a1	ATPase%2C Ca++ transporting%2C cardiac muscle%2C fast twitch 1 [Source:MGI Symbol%3BAcc:MGI:105058]	GO:0008637:apoptotic mitochondrial changes;GO:0070509:calcium ion import;GO:1990036:calcium ion import into sarcoplasmic reticulum;GO:0070588:calcium ion transmembrane transport;GO:0006816:calcium ion transport;GO:0006874:cellular calcium ion homeostasis;GO:0070059:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0051659:maintenance of mitochondrion location;GO:0032471:negative regulation of endoplasmic reticulum calcium ion concentration;GO:0045988:negative regulation of striated muscle contraction;GO:1901896:positive regulation of calcium-transporting ATPase activity;GO:1902082:positive regulation of calcium ion import into sarcoplasmic reticulum;GO:0032470:positive regulation of endoplasmic reticulum calcium ion concentration;GO:0031448:positive regulation of fast-twitch skeletal muscle fiber contraction;GO:0051561:positive regulation of mitochondrial calcium ion concentration;GO:0006937:regulation of muscle contraction;GO:0006942:regulation of striated muscle contraction;GO:0090076:relaxation of skeletal muscle;GO:0034976:response to endoplasmic reticulum stress;GO:0043434:response to peptide hormone;GO:0070296:sarcoplasmic reticulum calcium ion transport;	GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0005793:endoplasmic reticulum-Golgi intermediate compartment;GO:0031673:H zone;GO:0031674:I band;GO:0016021:integral component of membrane;GO:0043231:intracellular membrane-bounded organelle;GO:0016020:membrane;GO:0005739:mitochondrion;GO:0048471:perinuclear region of cytoplasm;GO:0016529:sarcoplasmic reticulum;GO:0033017:sarcoplasmic reticulum membrane;	GO:0005524:ATP binding;GO:0005509:calcium ion binding;GO:0030899:calcium-dependent ATPase activity;GO:0005338:nucleotide-sugar transmembrane transporter activity;GO:0005388:calcium-transporting ATPase activity;GO:0008553:hydrogen-exporting ATPase activity, phosphorylative mechanism;GO:0042803:protein homodimerization activity;	K05853	;ko04020 Calcium signaling pathway;ko04022 cGMP-PKG signaling pathway;ko04024 cAMP signaling pathway;ko04260 Cardiac muscle contraction;ko04261 Adrenergic signaling in cardiomyocytes;ko04919 Thyroid hormone signaling pathway;ko04972 Pancreatic secretion;ko05010 Alzheimer disease;ko05017 Spinocerebellar ataxia;ko05022 Pathways of neurodegeneration - multiple diseases;ko05410 Hypertrophic cardiomyopathy;ko05412 Arrhythmogenic right ventricular cardiomyopathy;ko05414 Dilated cardiomyopathy;
ENSMUSG00000024330	6874	232	1.75	281	2.33	121	0.81	96	0.83	179.452038994218	0.437760031788415	-1.19178785478806	0.255823802676963	-4.65862770515129	3.18324304582325e-06	7.6583162820902e-05	Down	17	34258411	34285659	+	Col11a2	collagen%2C type XI%2C alpha 2 [Source:MGI Symbol%3BAcc:MGI:88447]	GO:0051216:cartilage development;GO:0002062:chondrocyte differentiation;GO:0030199:collagen fibril organization;GO:0030198:extracellular matrix organization;GO:0001649:osteoblast differentiation;GO:0060021:palate development;GO:0007605:sensory perception of sound;GO:0001501:skeletal system development;GO:0048705:skeletal system morphogenesis;GO:0060023:soft palate development;GO:0001894:tissue homeostasis;	GO:0005581:collagen trimer;GO:0031012:extracellular matrix;GO:0005615:extracellular space;	GO:0005201:extracellular matrix structural constituent;GO:0046872:metal ion binding;	K19721	;ko04974 Protein digestion and absorption;
ENSMUSG00000111080	3440	242	3.65	276	4.57	109	1.46	109	1.89	181.433424284249	0.439430334026923	-1.18629363195435	0.254780416221016	-4.6561413532085	3.22190769643156e-06	7.73157004962154e-05	Down	10	30479191	30482630	-	Gm20300	predicted gene%2C 20300 [Source:MGI Symbol%3BAcc:MGI:5012485]	-	-	-	-	-
ENSMUSG00000097108	4479	60	0.70	45	0.57	4	0.04	8	0.11	28.5345649842499	0.12115976778768	-3.04501737667845	0.654257107102813	-4.65416018201533	3.25303845751671e-06	7.79407682930645e-05	Down	10	22088552	22093140	+	Gm26581	predicted gene%2C 26581 [Source:MGI Symbol%3BAcc:MGI:5477075]	-	-	-	-	-
ENSMUSG00000022468	2745	407	7.70	355	7.36	133	2.23	179	3.88	265.11975768617	0.434295451124304	-1.20325125302067	0.259067304682244	-4.64455078380694	3.4081720949646e-06	8.12766888090002e-05	Down	15	97608896	97629220	-	Endou	endonuclease%2C polyU-specific [Source:MGI Symbol%3BAcc:MGI:97746]	GO:0007565:female pregnancy;GO:0006955:immune response;GO:0006508:proteolysis;	GO:0005737:cytoplasm;GO:0005576:extracellular region;	GO:0004521:endoribonuclease activity;GO:0046872:metal ion binding;GO:0030247:polysaccharide binding;GO:0003723:RNA binding;GO:0005044:scavenger receptor activity;GO:0008236:serine-type peptidase activity;	K14648	-
ENSMUSG00000028982	1887	103	2.83	76	2.29	251	6.12	171	5.40	148.671899559567	2.43743110076461	1.28536143855862	0.27682092381234	4.64329582047774	3.42894844015757e-06	8.16451791636276e-05	Ups	4	149828493	149858734	-	Slc25a33	solute carrier family 25%2C member 33 [Source:MGI Symbol%3BAcc:MGI:1917806]	GO:0032869:cellular response to insulin stimulus;GO:1990314:cellular response to insulin-like growth factor stimulus;GO:0031930:mitochondria-nucleus signaling pathway;GO:0000002:mitochondrial genome maintenance;GO:0034551:mitochondrial respiratory chain complex III assembly;GO:0006390:transcription from mitochondrial promoter;GO:0007005:mitochondrion organization;GO:0030307:positive regulation of cell growth;GO:0008284:positive regulation of cell proliferation;GO:1990519:mitochondrial pyrimidine nucleotide import;GO:0006864:pyrimidine nucleotide transport;GO:0051881:regulation of mitochondrial membrane potential;GO:0002082:regulation of oxidative phosphorylation;GO:1903426:regulation of reactive oxygen species biosynthetic process;	GO:0016021:integral component of membrane;GO:0005743:mitochondrial inner membrane;GO:0031966:mitochondrial membrane;GO:0005739:mitochondrion;	GO:0015218:pyrimidine nucleotide transmembrane transporter activity;	K15116	-
ENSMUSG00000051550	4159	203	2.53	260	3.56	111	1.23	65	0.93	156.420496982085	0.388905049197054	-1.36251012932516	0.29353227976303	-4.64177272232249	3.45432701941429e-06	8.19948150397813e-05	Down	7	4986482	4999157	-	Zfp579	zinc finger protein 579 [Source:MGI Symbol%3BAcc:MGI:1915740]	-	GO:0005634:nucleus;	GO:0003677:DNA binding;GO:0046872:metal ion binding;	-	-
ENSMUSG00000112292	424	3	0.37	5	0.67	38	4.12	46	6.46	23.5274002875589	11.0572229672875	3.4669171916365	0.748233482032154	4.63346973222927	3.59587354846974e-06	8.49601309587597e-05	Ups	12	80026202	80026625	-	Gm8275	predicted gene 8275 [Source:MGI Symbol%3BAcc:MGI:3648021]	GO:0006915:apoptotic process;GO:0045445:myoblast differentiation;GO:0002317:plasma cell differentiation;GO:0046598:positive regulation of viral entry into host cell;GO:0031295:T cell costimulation;	GO:0005737:cytoplasm;GO:0005615:extracellular space;	GO:0030246:carbohydrate binding;	K06830	-
ENSMUSG00000044350	3644	416	5.93	341	5.33	181	2.29	178	2.91	274.500249419546	0.497071219516536	-1.00847552140526	0.217827733281405	-4.62969295145924	3.66208348139996e-06	8.63913663135184e-05	Down	14	77261640	77274344	-	Lacc1	laccase domain containing 1 [Source:MGI Symbol%3BAcc:MGI:2445077]	GO:0006954:inflammatory response;GO:0045087:innate immune response;GO:0070431:nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0002221:pattern recognition receptor signaling pathway;GO:0002720:positive regulation of cytokine production involved in immune response;GO:0030641:regulation of cellular pH;GO:0050727:regulation of inflammatory response;GO:1900542:regulation of purine nucleotide metabolic process;	GO:0005737:cytoplasm;GO:0005783:endoplasmic reticulum;GO:0005634:nucleus;GO:0005777:peroxisome;	GO:0004000:adenosine deaminase activity;GO:0005507:copper ion binding;GO:0047975:guanosine phosphorylase activity;GO:0004731:purine-nucleoside phosphorylase activity;GO:0017061:S-methyl-5-thioadenosine phosphorylase activity;	K05810	-
ENSMUSG00000027863	1741	229	6.83	207	6.77	108	2.85	51	1.74	144.728207266084	0.372069969105922	-1.42635414401082	0.3081116665516	-4.62934156299449	3.66830268190698e-06	8.64051510358857e-05	Down	3	101183215	101195255	-	Cd2	CD2 antigen [Source:MGI Symbol%3BAcc:MGI:88320]	GO:0098609:cell-cell adhesion;GO:0034113:heterotypic cell-cell adhesion;GO:0032729:positive regulation of interferon-gamma production;GO:0032757:positive regulation of interleukin-8 production;GO:0032760:positive regulation of tumor necrosis factor production;GO:0042110:T cell activation;	GO:0046658:anchored component of plasma membrane;GO:0009986:cell surface;GO:0005911:cell-cell junction;GO:0009898:cytoplasmic side of plasma membrane;GO:0009897:external side of plasma membrane;GO:0005576:extracellular region;GO:0016021:integral component of membrane;GO:0045121:membrane raft;GO:0032991:macromolecular complex;	GO:0042802:identical protein binding;GO:0019901:protein kinase binding;GO:0043621:protein self-association;GO:0030971:receptor tyrosine kinase binding;GO:0005102:receptor binding;	K06449	;ko04514 Cell adhesion molecules;ko04640 Hematopoietic cell lineage;
ENSMUSG00000014075	2385	232	5.05	177	4.22	515	9.94	319	7.97	306.283536627816	2.0988080421616	1.06957022318771	0.231300981548661	4.62414908932279	3.7613926272557e-06	8.79968431590397e-05	Ups	16	32238520	32247917	+	Dynlt2b	dynein light chain Tctex-type 2B [Source:MGI Symbol%3BAcc:MGI:1913311]	GO:0060271:cilium morphogenesis;GO:0035721:intraciliary retrograde transport;GO:1902017:regulation of cilium assembly;	GO:0005929:cilium;GO:0005737:cytoplasm;GO:0005868:cytoplasmic dynein complex;	GO:0045505:dynein intermediate chain binding;	-	-
ENSMUSG00000074146	3676	8	0.11	7	0.11	43	0.54	61	0.99	30.5415619830215	7.37236459161302	2.88212741951795	0.623767162927261	4.62051802469449	3.82783084960878e-06	8.92035839633754e-05	Ups	9	88995164	89059940	-	4930579C12Rik	RIKEN cDNA 4930579C12 gene [Source:MGI Symbol%3BAcc:MGI:2441687]	-	-	-	-	-
ENSMUSG00000036552	7247	365	2.61	391	3.07	181	1.15	180	1.48	275.508605457664	0.499057706810993	-1.00272144863043	0.217162505987182	-4.61737832722198	3.8861839726798e-06	8.98330227637349e-05	Down	17	15261470	15310306	+	Ermard	ER membrane associated RNA degradation [Source:MGI Symbol%3BAcc:MGI:1917317]	-	GO:0005789:endoplasmic reticulum membrane;GO:0016021:integral component of membrane;	-	-	-
ENSMUSG00000032489	4298	143	1.73	134	1.77	50	0.54	45	0.62	91.2215633430023	0.357466072006652	-1.48412177627061	0.321456776315033	-4.61686262546275	3.89584975465526e-06	8.98330227637349e-05	Down	9	110306026	110354247	+	Kif9	kinesin family member 9 [Source:MGI Symbol%3BAcc:MGI:1098237]	GO:0022617:extracellular matrix disassembly;GO:0007018:microtubule-based movement;GO:1903008:organelle disassembly;GO:0071801:regulation of podosome assembly;	GO:0005829:cytosol;GO:0005871:kinesin complex;GO:0005874:microtubule;GO:0002102:podosome;GO:0031982:vesicle;	GO:0005524:ATP binding;GO:0042802:identical protein binding;GO:0008017:microtubule binding;GO:0003777:microtubule motor activity;	K10397	-
ENSMUSG00000112148	5227	398	3.95	303	3.30	152	1.34	160	1.82	249.08233908479	0.468182443634344	-1.09485725902043	0.238065297625396	-4.59897880934845	4.24566961017576e-06	9.6739327681014e-05	Down	10	51367052	51372707	+	Lilrb4a	leukocyte immunoglobulin-like receptor%2C subfamily B%2C member 4A [Source:MGI Symbol%3BAcc:MGI:102701]	GO:0002250:adaptive immune response;GO:0007596:blood coagulation;GO:0035739:CD4-positive, alpha-beta T cell proliferation;GO:0035740:CD8-positive, alpha-beta T cell proliferation;GO:0071222:cellular response to lipopolysaccharide;GO:0006954:inflammatory response;GO:0002437:inflammatory response to antigenic stimulus;GO:0033007:negative regulation of mast cell activation involved in immune response;GO:0001780:neutrophil homeostasis;GO:0009991:response to extracellular stimulus;GO:0032496:response to lipopolysaccharide;GO:0009624:response to nematode;GO:0051707:response to other organism;GO:0009611:response to wounding;GO:0042092:type 2 immune response;	GO:0009986:cell surface;GO:0009897:external side of plasma membrane;GO:0016021:integral component of membrane;	GO:0005178:integrin binding;GO:0019903:protein phosphatase binding;GO:0030547:receptor inhibitor activity;GO:0030293:transmembrane receptor protein tyrosine kinase inhibitor activity;	K06512	;ko04380 Osteoclast differentiation;ko04662 B cell receptor signaling pathway;
ENSMUSG00000064339	1582	20606	676.20	11716	421.44	32556	946.95	31400	1182.09	24029.9577032331	2.08699060278976	1.06142410440808	0.230802123550216	4.59884895373222	4.2483164930783e-06	9.6739327681014e-05	Ups	MT	1094	2675	+	mt-Rnr2	mitochondrially encoded 16S rRNA [Source:MGI Symbol%3BAcc:MGI:102492]	-	-	-	-	-
ENSMUSG00000027550	7475	1170	8.13	1118	8.51	434	2.67	603	4.80	823.022858920326	0.482092013540239	-1.05261956501076	0.228901399244985	-4.59857199861055	4.2539670292954e-06	9.6739327681014e-05	Down	3	14598848	14637718	+	Lrrcc1	leucine rich repeat and coiled-coil domain containing 1 [Source:MGI Symbol%3BAcc:MGI:1918960]	GO:0007049:cell cycle;GO:0051301:cell division;	GO:0005814:centriole;GO:0005813:centrosome;GO:0005737:cytoplasm;	-	K16475	-
ENSMUSG00000015474	2614	93	1.85	105	2.29	34	0.60	18	0.41	60.9779663577716	0.269058513609529	-1.894008137294	0.412579609026921	-4.59064892169796	4.41870049283125e-06	9.96928147333024e-05	Down	17	34835636	34847484	-	Ppt2	palmitoyl-protein thioesterase 2 [Source:MGI Symbol%3BAcc:MGI:1860075]	-	GO:0043231:intracellular membrane-bounded organelle;GO:0005764:lysosome;	GO:0098599:palmitoyl hydrolase activity;GO:0008474:palmitoyl-(protein) hydrolase activity;GO:0016790:thiolester hydrolase activity;	K01074	;ko00062 Fatty acid elongation;ko01100 Metabolic pathways;ko01212 Fatty acid metabolism;ko04142 Lysosome;
ENSMUSG00000062785	5995	169	1.46	192	1.82	443	3.40	287	2.85	269.690179917977	2.07628520760393	1.05400463219966	0.229857634209691	4.58546715589237	4.52972480885874e-06	0.000101696632824363	Ups	7	44240088	44254178	+	Kcnc3	potassium voltage gated channel%2C Shaw-related subfamily%2C member 3 [Source:MGI Symbol%3BAcc:MGI:96669]	GO:0071805:potassium ion transmembrane transport;GO:0051260:protein homooligomerization;GO:0051262:protein tetramerization;GO:0034765:regulation of ion transmembrane transport;GO:0046928:regulation of neurotransmitter secretion;	GO:0030673:axolemma;GO:0030424:axon;GO:0043679:axon terminus;GO:0005938:cell cortex;GO:0005856:cytoskeleton;GO:0032590:dendrite membrane;GO:0032591:dendritic spine membrane;GO:0016021:integral component of membrane;GO:0031594:neuromuscular junction;GO:0032809:neuronal cell body membrane;GO:0043204:perikaryon;GO:0005886:plasma membrane;GO:0008076:voltage-gated potassium channel complex;GO:0045211:postsynaptic membrane;GO:0042734:presynaptic membrane;	GO:0005251:delayed rectifier potassium channel activity;GO:0005249:voltage-gated potassium channel activity;	K04889	;ko05017 Spinocerebellar ataxia;
ENSMUSG00000097343	2398	22	0.48	35	0.83	114	2.19	86	2.14	64.1261402654458	3.61771784621356	1.85507989338152	0.405115548674538	4.57913772860853	4.66896695902792e-06	0.000104364343075414	Ups	7	120272659	120276793	-	9030407P20Rik	RIKEN cDNA 9030407P20 gene [Source:MGI Symbol%3BAcc:MGI:1918818]	-	-	-	-	-
ENSMUSG00000021238	5784	291	2.61	279	2.74	138	1.10	127	1.31	205.427710020996	0.48502269359091	-1.04387584415435	0.229004775414925	-4.55831474371217	5.15657209054643e-06	0.000113444585992021	Down	12	84477491	84497778	-	Aldh6a1	aldehyde dehydrogenase family 6%2C subfamily A1 [Source:MGI Symbol%3BAcc:MGI:1915077]	GO:0006210:thymine catabolic process;GO:0019859:thymine metabolic process;GO:0006574:valine catabolic process;GO:0006573:valine metabolic process;GO:0019484:beta-alanine catabolic process;GO:0050873:brown fat cell differentiation;	GO:0005739:mitochondrion;GO:0005654:nucleoplasm;	GO:0000062:fatty-acyl-CoA binding;GO:0018478:malonate-semialdehyde dehydrogenase (acetylating) activity;GO:0004491:methylmalonate-semialdehyde dehydrogenase (acylating) activity;GO:0016790:thiolester hydrolase activity;	K00140	;ko00280 Valine, leucine and isoleucine degradation;ko00410 beta-Alanine metabolism;ko00562 Inositol phosphate metabolism;ko00640 Propanoate metabolism;ko01100 Metabolic pathways;ko01200 Carbon metabolism;
ENSMUSG00000045136	2294	116	2.63	120	2.98	45	0.90	29	0.75	75.7444972781928	0.323227678087745	-1.62937735307789	0.357808991449335	-4.55376301886087	5.26947151423102e-06	0.000115266870469641	Down	13	34310731	34314449	-	Tubb2b	tubulin%2C beta 2B class IIB [Source:MGI Symbol%3BAcc:MGI:1920960]	GO:0051301:cell division;GO:0009987:cellular process;GO:0030705:cytoskeleton-dependent intracellular transport;GO:0000226:microtubule cytoskeleton organization;GO:0007017:microtubule-based process;GO:0000278:mitotic cell cycle;GO:0042267:natural killer cell mediated cytotoxicity;GO:0050807:regulation of synapse organization;GO:0051225:spindle assembly;GO:1990403:embryonic brain development;GO:0050804:regulation of synaptic transmission;GO:0031115:negative regulation of microtubule polymerization;GO:0001764:neuron migration;GO:1902669:positive regulation of axon guidance;	GO:0035578:azurophil granule lumen;GO:0044297:cell body;GO:0005737:cytoplasm;GO:0036464:cytoplasmic ribonucleoprotein granule;GO:0005856:cytoskeleton;GO:0005829:cytosol;GO:0070062:extracellular exosome;GO:0005576:extracellular region;GO:0045121:membrane raft;GO:0005874:microtubule;GO:0005641:nuclear envelope lumen;GO:0005634:nucleus;GO:0032991:macromolecular complex;	GO:0005525:GTP binding;GO:0032794:GTPase activating protein binding;GO:0042288:MHC class I protein binding;GO:0019904:protein domain specific binding;GO:0044877:macromolecular complex binding;GO:0005200:structural constituent of cytoskeleton;GO:0005198:structural molecule activity;GO:0031625:ubiquitin protein ligase binding;GO:0005509:calcium ion binding;GO:0046982:protein heterodimerization activity;	K07375	;ko04145 Phagosome;ko04540 Gap junction;ko05010 Alzheimer disease;ko05012 Parkinson disease;ko05014 Amyotrophic lateral sclerosis;ko05016 Huntington disease;ko05020 Prion disease;ko05022 Pathways of neurodegeneration - multiple diseases;ko05130 Pathogenic Escherichia coli infection;ko05132 Salmonella infection;
ENSMUSG00000020319	5934	90	0.79	92	0.88	30	0.23	17	0.17	55.8275301240456	0.265468936295603	-1.91338504016381	0.420335718291255	-4.55204008819923	5.31282088037902e-06	0.000115884488449121	Down	11	21522235	21848989	+	Wdpcp	WD repeat containing planar cell polarity effector [Source:MGI Symbol%3BAcc:MGI:2144467]	GO:0002093:auditory receptor cell morphogenesis;GO:0043010:camera-type eye development;GO:0060271:cilium morphogenesis;GO:0044782:cilium organization;GO:0072359:circulatory system development;GO:0055123:digestive system development;GO:0042733:embryonic digit morphogenesis;GO:0048568:embryonic organ development;GO:0045184:establishment of protein localization;GO:0090521:glomerular visceral epithelial cell migration;GO:0001822:kidney development;GO:0007399:nervous system development;GO:0016476:regulation of embryonic cell shape;GO:2000114:regulation of establishment of cell polarity;GO:0010762:regulation of fibroblast migration;GO:0051893:regulation of focal adhesion assembly;GO:0032880:regulation of protein localization;GO:1900027:regulation of ruffle assembly;GO:0060541:respiratory system development;GO:0060021:palate development;GO:0032185:septin cytoskeleton organization;GO:0007224:smoothened signaling pathway;GO:0043587:tongue morphogenesis;	GO:0097541:axonemal basal plate;GO:0005930:axoneme;GO:0005886:plasma membrane;	-	-	-
ENSMUSG00000020396	3994	119	1.55	77	1.10	241	2.78	206	3.07	160.165952795589	2.38341121716958	1.25302788555663	0.275304061918185	4.5514326117317	5.32818639622198e-06	0.00011605455994271	Ups	11	4888754	4898064	-	Nefh	neurofilament%2C heavy polypeptide [Source:MGI Symbol%3BAcc:MGI:97309]	GO:0061564:axon development;GO:0031103:axon regeneration;GO:0007420:brain development;GO:0045110:intermediate filament bundle assembly;GO:0045104:intermediate filament cytoskeleton organization;GO:0000226:microtubule cytoskeleton organization;GO:0033693:neurofilament bundle assembly;GO:0060052:neurofilament cytoskeleton organization;GO:0001552:ovarian follicle atresia;GO:0048936:peripheral nervous system neuron axonogenesis;GO:1902513:regulation of organelle transport along microtubule;GO:1903935:response to sodium arsenite;	GO:0097440:apical dendrite;GO:0030424:axon;GO:0005737:cytoplasm;GO:0005856:cytoskeleton;GO:0005882:intermediate filament;GO:0005739:mitochondrion;GO:0043209:myelin sheath;GO:0097418:neurofibrillary tangle;GO:0005883:neurofilament;GO:0043025:neuronal cell body;GO:0005634:nucleus;GO:0043204:perikaryon;GO:0014069:postsynaptic density;	GO:0019901:protein kinase binding;GO:0044877:macromolecular complex binding;GO:0030674:protein binding, bridging;GO:0005200:structural constituent of cytoskeleton;GO:0015643:toxic substance binding;	K04574	;ko05014 Amyotrophic lateral sclerosis;ko05022 Pathways of neurodegeneration - multiple diseases;
ENSMUSG00000061578	13619	603	2.30	442	1.85	190	0.64	251	1.10	366.256304718435	0.448805979482719	-1.1558361976559	0.253990900180126	-4.55069924487926	5.34679287578564e-06	0.00011629464107418	Down	5	117552036	117913068	+	Ksr2	kinase suppressor of ras 2 [Source:MGI Symbol%3BAcc:MGI:3610315]	GO:0019722:calcium-mediated signaling;GO:0043410:positive regulation of MAPK cascade;GO:0007265:Ras protein signal transduction;GO:0007165:signal transduction;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005886:plasma membrane;	GO:0005524:ATP binding;GO:0005078:MAP-kinase scaffold activity;GO:0046872:metal ion binding;GO:0031434:mitogen-activated protein kinase kinase binding;GO:0004672:protein kinase activity;	K18529	;ko04013 MAPK signaling pathway - fly;ko04014 Ras signaling pathway;
ENSMUSG00000047712	4626	28	0.31	22	0.27	116	1.15	68	0.88	57.7324110453008	3.77905984010304	1.91802736335479	0.421565466561145	4.54977344088642	5.37037058600378e-06	0.000116642014965697	Ups	10	8080520	8394589	-	Ust	uronyl-2-sulfotransferase [Source:MGI Symbol%3BAcc:MGI:2442406]	GO:0030010:establishment of cell polarity;GO:0050770:regulation of axonogenesis;	GO:0000139:Golgi membrane;GO:0016021:integral component of membrane;	GO:0008146:sulfotransferase activity;	K03193	;ko00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate;
ENSMUSG00000033949	4933	458	4.82	452	5.21	194	1.81	230	2.78	329.610661402536	0.491044947421883	-1.02607300832138	0.225567660017418	-4.548848040726	5.39403746998785e-06	0.000116990340261377	Down	18	46298367	46345674	-	Trim36	tripartite motif-containing 36 [Source:MGI Symbol%3BAcc:MGI:106264]	GO:0007340:acrosome reaction;GO:0001578:microtubule bundle formation;GO:0000281:mitotic cytokinesis;GO:0051726:regulation of cell cycle;GO:0070507:regulation of microtubule cytoskeleton organization;GO:0007051:spindle organization;	GO:0001669:acrosomal vesicle;GO:0005737:cytoplasm;GO:0015630:microtubule cytoskeleton;	GO:0043014:alpha-tubulin binding;GO:0004842:ubiquitin-protein transferase activity;GO:0008270:zinc ion binding;	K12013	-
ENSMUSG00000025810	9785	154	0.82	98	0.57	42	0.20	33	0.20	79.6433882231138	0.310351293430202	-1.68802593633271	0.371304402914603	-4.54620500883461	5.46218349903655e-06	0.00011813416329228	Down	8	129085085	129229844	+	Nrp1	neuropilin 1 [Source:MGI Symbol%3BAcc:MGI:106206]	GO:0031532:actin cytoskeleton reorganization;GO:0001525:angiogenesis;GO:0060978:angiogenesis involved in coronary vascular morphogenesis;GO:0048844:artery morphogenesis;	GO:0030424:axon;GO:0009986:cell surface;GO:0005829:cytosol;GO:0005769:early endosome;	GO:0019838:growth factor binding;GO:0005096:GTPase activator activity;GO:0008201:heparin binding;GO:0046872:metal ion binding;	K06724	;ko04360 Axon guidance;ko05166 Human T-cell leukemia virus 1 infection;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000111722	791	8	0.53	6	0.43	49	2.85	46	3.46	27.4841953538587	7.10005219451917	2.82782963032115	0.622815859928654	4.54039438020266	5.61491012170088e-06	0.000120925606469328	Ups	9	65360897	65367681	+	Gm47270	predicted gene%2C 47270 [Source:MGI Symbol%3BAcc:MGI:6096107]	-	-	-	-	-
ENSMUSG00000049047	3540	199	2.92	169	2.72	70	0.91	72	1.21	125.297016906528	0.4045395746338	-1.30564725172486	0.287703206415792	-4.53817414129868	5.67433941373117e-06	0.000122034110196569	Down	X	133657344	133662204	+	Armcx3	armadillo repeat containing%2C X-linked 3 [Source:MGI Symbol%3BAcc:MGI:1918953]	GO:0019896:axon transport of mitochondrion;GO:0034613:cellular protein localization;GO:0007005:mitochondrion organization;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;	GO:1904115:axon cytoplasm;GO:0005829:cytosol;GO:0031307:integral component of mitochondrial outer membrane;GO:0005739:mitochondrion;GO:0005634:nucleus;	-	-	-
ENSMUSG00000028655	2250	157	3.62	85	2.15	390	7.98	223	5.90	210.112001498431	2.60753843006313	1.38268851543073	0.306887894938197	4.5055166340438	6.6211651924871e-06	0.000141012426474441	Ups	4	122840643	122854981	-	Mfsd2a	major facilitator superfamily domain containing 2A [Source:MGI Symbol%3BAcc:MGI:1923824]	GO:0007420:brain development;GO:0008643:carbohydrate transport;GO:0009267:cellular response to starvation;GO:0050890:cognition;GO:0097009:energy homeostasis;GO:0060856:establishment of blood-brain barrier;GO:0015908:fatty acid transport;GO:0021766:hippocampus development;GO:1990379:lipid transport across blood brain barrier;GO:0015909:long-chain fatty acid transport;GO:0051977:lysophospholipid transport;GO:0035633:maintenance of blood-brain barrier;GO:0031999:negative regulation of fatty acid beta-oxidation;GO:0071702:organic substance transport;GO:0008594:photoreceptor cell morphogenesis;GO:0035845:photoreceptor cell outer segment organization;GO:0030307:positive regulation of cell growth;GO:0010867:positive regulation of triglyceride biosynthetic process;GO:0050773:regulation of dendrite development;GO:0040014:regulation of multicellular organism growth;GO:0060042:retina morphogenesis in camera-type eye;GO:0003406:retinal pigment epithelium development;GO:0045056:transcytosis;GO:0034379:very-low-density lipoprotein particle assembly;GO:0006656:phosphatidylcholine biosynthetic process;	GO:0005789:endoplasmic reticulum membrane;GO:0005887:integral component of plasma membrane;GO:0005886:plasma membrane;GO:0016021:integral component of membrane;	GO:0015245:fatty acid transporter activity;GO:0005324:long-chain fatty acid transporter activity;GO:0051978:lysophospholipid transporter activity;GO:1901480:oleate transporter activity;GO:0015293:symporter activity;GO:0005548:phospholipid transporter activity;	-	-
ENSMUSG00000037151	3216	298	4.81	269	4.76	122	1.75	131	2.43	202.0223924953	0.468495179420775	-1.09389389153123	0.243074487963865	-4.50024147204557	6.78763118865835e-06	0.0001437590285178	Down	10	61311580	61418570	+	Lrrc20	leucine rich repeat containing 20 [Source:MGI Symbol%3BAcc:MGI:2387182]	-	-	-	-	-
ENSMUSG00000025433	1417	119	4.36	169	6.79	53	1.72	41	1.72	93.8691833126626	0.336889324560332	-1.56965338221246	0.349091339918984	-4.49639736859913	6.91145165281538e-06	0.000145777441051267	Down	17	40532668	40553179	-	Crisp3	cysteine-rich secretory protein 3 [Source:MGI Symbol%3BAcc:MGI:102552]	-	GO:0005615:extracellular space;GO:0030133:transport vesicle;	-	-	-
ENSMUSG00000006442	1599	1586	51.49	1042	37.08	3293	94.76	1850	68.90	1907.25474841965	2.00796563933704	1.00573458184735	0.223952873558573	4.49083133369267	7.09457170236079e-06	0.000149032131247081	Ups	4	148675960	148679450	+	Srm	spermidine synthase [Source:MGI Symbol%3BAcc:MGI:102690]	GO:0006596:polyamine biosynthetic process;GO:0008295:spermidine biosynthetic process;	-	GO:0042802:identical protein binding;GO:0042803:protein homodimerization activity;GO:0004766:spermidine synthase activity;	K00797	;ko00270 Cysteine and methionine metabolism;ko00330 Arginine and proline metabolism;ko00480 Glutathione metabolism;ko01100 Metabolic pathways;
ENSMUSG00000029009	7315	361	2.56	453	3.52	232	1.46	143	1.16	291.432279756677	0.47174948700017	-1.08390714590682	0.241870856121569	-4.48134662971561	7.4173527130912e-06	0.000154813858253089	Down	4	148123534	148144008	+	Mthfr	methylenetetrahydrofolate reductase [Source:MGI Symbol%3BAcc:MGI:106639]	GO:0070829:heterochromatin maintenance;GO:0050667:homocysteine metabolic process;GO:0009086:methionine biosynthetic process;GO:0006555:methionine metabolic process;GO:0001843:neural tube closure;GO:0031060:regulation of histone methylation;GO:0035999:tetrahydrofolate interconversion;GO:0046653:tetrahydrofolate metabolic process;	GO:0005829:cytosol;GO:0045202:synapse;	GO:0071949:FAD binding;GO:0050660:flavin adenine dinucleotide binding;GO:0004489:methylenetetrahydrofolate reductase (NAD(P)H) activity;GO:0072341:modified amino acid binding;GO:0050661:NADP binding;GO:0044877:macromolecular complex binding;	K00297	;ko00670 One carbon pool by folate;ko00720 Carbon fixation pathways in prokaryotes;ko01100 Metabolic pathways;ko01120 Microbial metabolism in diverse environments;ko01200 Carbon metabolism;ko01523 Antifolate resistance;
ENSMUSG00000036002	4129	170	2.14	254	3.50	91	1.01	66	0.95	142.822608870692	0.380948578145566	-1.39233182436329	0.310701530061734	-4.48125190785717	7.4206460033925e-06	0.000154813858253089	Down	4	43032414	43046220	-	Fam214b	family with sequence similarity 214%2C member B [Source:MGI Symbol%3BAcc:MGI:2441854]	-	GO:0005634:nucleus;	-	-	-
ENSMUSG00000073492	2574	204	4.11	196	4.33	55	0.98	83	1.92	132.837933288519	0.36628445606198	-1.44896361589417	0.323687869631241	-4.47642235572465	7.59042548694346e-06	0.0001566508538584	Down	1	171723231	171725804	+	Gm10521	predicted gene 10521 [Source:MGI Symbol%3BAcc:MGI:3642358]	-	-	-	-	-
ENSMUSG00000043415	2832	310	5.68	408	8.20	177	2.88	152	3.20	258.044910732404	0.475052795030819	-1.07384023850363	0.239976952720562	-4.47476404017037	7.64957429920124e-06	0.000157659371376279	Down	2	19662563	19665394	+	Otud1	OTU domain containing 1 [Source:MGI Symbol%3BAcc:MGI:1918448]	GO:0016579:protein deubiquitination;GO:0070536:protein K63-linked deubiquitination;	-	GO:0004843:ubiquitin-specific protease activity;	K13716	-
ENSMUSG00000025464	4907	227	2.40	240	2.78	118	1.11	89	1.08	165.396869371103	0.458722113215055	-1.12430763905516	0.251289573725144	-4.47415156302867	7.67153137695656e-06	0.000157899680717117	Down	7	139695712	139717137	+	Paox	polyamine oxidase (exo-N4-amino) [Source:MGI Symbol%3BAcc:MGI:1916983]	GO:0006598:polyamine catabolic process;GO:1901307:positive regulation of spermidine biosynthetic process;GO:0009446:putrescine biosynthetic process;GO:0009447:putrescine catabolic process;GO:0046203:spermidine catabolic process;GO:0046208:spermine catabolic process;	GO:0005782:peroxisomal matrix;	GO:0052899:N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity;GO:0052904:N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity;GO:0052903:N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity;GO:0016491:oxidoreductase activity;GO:0046592:polyamine oxidase activity;GO:0052902:spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity;GO:0052901:spermine:oxygen oxidoreductase (spermidine-forming) activity;	K00308	;ko04146 Peroxisome;
ENSMUSG00000031755	3311	211	3.31	159	2.73	60	0.83	73	1.31	123.612525890734	0.37971636928783	-1.39700590108881	0.312536847515545	-4.46989182937646	7.82591663889438e-06	0.000160861401797328	Down	8	94794582	94825556	-	Bbs2	Bardet-Biedl syndrome 2 (human) [Source:MGI Symbol%3BAcc:MGI:2135267]	GO:0030534:adult behavior;GO:0014824:artery smooth muscle contraction;GO:0048854:brain morphogenesis;GO:0051216:cartilage development;GO:0021987:cerebral cortex development;GO:0060271:cilium morphogenesis;GO:0045444:fat cell differentiation;GO:0043001:Golgi to plasma membrane protein transport;GO:0021766:hippocampus development;GO:0033210:leptin-mediated signaling pathway;GO:0038108:negative regulation of appetite by leptin-mediated signaling pathway;GO:0010629:negative regulation of gene expression;GO:0040015:negative regulation of multicellular organism growth;GO:0045494:photoreceptor cell maintenance;GO:0040018:positive regulation of multicellular organism growth;GO:0008104:protein localization;GO:1903441:protein localization to ciliary membrane;GO:0033365:protein localization to organelle;GO:0060296:regulation of cilium beat frequency involved in ciliary motility;GO:0044321:response to leptin;GO:0007288:sperm axoneme assembly;GO:0021756:striatum development;GO:0042311:vasodilation;GO:0007601:visual perception;	GO:0034464:BBSome;GO:0036064:ciliary basal body;GO:0060170:ciliary membrane;GO:0005737:cytoplasm;GO:0016020:membrane;GO:0005902:microvillus;GO:0031514:motile cilium;GO:0043005:neuron projection;GO:0032420:stereocilium;	GO:0061629:RNA polymerase II sequence-specific DNA binding transcription factor binding;	K16747	-
ENSMUSG00000021411	2914	625	11.13	868	16.95	438	6.92	286	5.85	544.527333157602	0.496538730271747	-1.0100218418029	0.226210714430784	-4.46496022235034	8.00836290035736e-06	0.000164171439457326	Down	13	34811817	34837469	-	Pxdc1	PX domain containing 1 [Source:MGI Symbol%3BAcc:MGI:1914145]	-	-	GO:0035091:phosphatidylinositol binding;	-	-
ENSMUSG00000022231	18686	39	0.11	55	0.17	5	0.01	6	0.02	25.7489212038068	0.121938939159856	-3.03576919483391	0.680341325251979	-4.46212670340075	8.11502168363196e-06	0.000166135837779456	Down	15	32244956	32696487	+	Sema5a	sema domain%2C seven thrombospondin repeats (type 1 and type 1-like)%2C transmembrane domain (TM) and short cytoplasmic domain%2C (semaphorin) 5A [Source:MGI Symbol%3BAcc:MGI:107556]	GO:0048675:axon extension;GO:0007411:axon guidance;GO:0007413:axonal fasciculation;GO:0002043:blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0001569:patterning of blood vessels;GO:0048754:branching morphogenesis of an epithelial tube;GO:0060326:cell chemotaxis;GO:0050908:detection of light stimulus involved in visual perception;GO:0021536:diencephalon development;GO:0048843:negative regulation of axon extension involved in axon guidance;GO:0007162:negative regulation of cell adhesion;GO:2000352:negative regulation of endothelial cell apoptotic process;GO:0001755:neural crest cell migration;GO:1990138:neuron projection extension;GO:0097485:neuron projection guidance;GO:0050918:positive chemotaxis;GO:0030836:positive regulation of actin filament depolymerization;GO:0045766:positive regulation of angiogenesis;GO:0048842:positive regulation of axon extension involved in axon guidance;GO:0090263:positive regulation of canonical Wnt signaling pathway;GO:0030335:positive regulation of cell migration;GO:2001028:positive regulation of endothelial cell chemotaxis;GO:0001938:positive regulation of endothelial cell proliferation;GO:0090091:positive regulation of extracellular matrix disassembly;GO:0051897:positive regulation of protein kinase B signaling;GO:0071526:semaphorin-plexin signaling pathway;GO:1990256:signal clustering;	GO:0016021:integral component of membrane;GO:0016020:membrane;	GO:0008046:axon guidance receptor activity;GO:0045499:chemorepellent activity;GO:0035373:chondroitin sulfate proteoglycan binding;GO:0043395:heparan sulfate proteoglycan binding;GO:0030215:semaphorin receptor binding;GO:0045545:syndecan binding;	K06841	;ko04360 Axon guidance;
ENSMUSG00000087179	7090	341	2.50	353	2.83	159	1.03	169	1.42	252.238007610936	0.495383018267496	-1.01338368104912	0.22749032068149	-4.45462329128263	8.40406239442625e-06	0.000170685950670374	Down	2	156644136	156681821	-	5730471H19Rik	RIKEN cDNA 5730471H19 gene [Source:MGI Symbol%3BAcc:MGI:3642639]	-	-	-	-	-
ENSMUSG00000046636	801	39	2.53	52	3.69	4	0.23	6	0.45	24.770377293576	0.115023949445642	-3.11999381502941	0.700612068449972	-4.45324018173432	8.45840459014703e-06	0.000171335767483903	Down	18	27731697	27732809	+	Gm7729	predicted gene 7729 [Source:MGI Symbol%3BAcc:MGI:3647361]	GO:0042149:cellular response to glucose starvation;GO:1903936:cellular response to sodium arsenite;GO:0051170:nuclear import;GO:0000398:mRNA splicing, via spliceosome;GO:0051028:mRNA transport;GO:0032211:negative regulation of telomere maintenance via telomerase;GO:0051168:nuclear export;GO:0032212:positive regulation of telomere maintenance via telomerase;GO:0000381:regulation of alternative mRNA splicing, via spliceosome;GO:0006405:RNA export from nucleus;	GO:0071013:catalytic step 2 spliceosome;GO:0005737:cytoplasm;GO:0070062:extracellular exosome;GO:0016020:membrane;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0005681:spliceosomal complex;	GO:0098505:G-rich strand telomeric DNA binding;GO:0042802:identical protein binding;GO:0035198:miRNA binding;GO:0036002:pre-mRNA binding;GO:0019904:protein domain specific binding;GO:0003723:RNA binding;GO:0003697:single-stranded DNA binding;GO:0003727:single-stranded RNA binding;	K12741	;ko03040 Spliceosome;ko05014 Amyotrophic lateral sclerosis;
ENSMUSG00000046408	1957	13	0.34	21	0.61	82	1.93	62	1.89	44.4567046393962	4.36879393686775	2.12723505971439	0.477741035630943	4.45269487245321	8.47992189273308e-06	0.000171545016231094	Ups	8	84728131	84731399	+	1700067K01Rik	RIKEN cDNA 1700067K01 gene [Source:MGI Symbol%3BAcc:MGI:1920703]	GO:0001701:in utero embryonic development;	-	-	-	-
ENSMUSG00000038543	1402	321	11.89	305	12.38	181	5.94	116	4.93	225.80413803456	0.488662783339778	-1.03308886207625	0.2322061985611	-4.44901500682554	8.62649893981685e-06	0.000174280282929053	Down	3	95791266	95799317	-	BC028528	cDNA sequence BC028528 [Source:MGI Symbol%3BAcc:MGI:2385885]	-	GO:0005576:extracellular region;	-	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000097233	3877	122	1.63	74	1.09	25	0.30	25	0.38	59.9664044843216	0.268093981168126	-1.89918926436349	0.428277040960424	-4.4344876860653	9.22914945222725e-06	0.000184510792308282	Down	19	4219565	4224283	+	Gm17552	predicted gene%2C 17552 [Source:MGI Symbol%3BAcc:MGI:4937186]	-	-	-	-	-
ENSMUSG00000107230	1395	17	0.63	23	0.94	83	2.74	69	2.95	48.0828760365262	3.93995955443689	1.9781808198053	0.44713808748727	4.42409375350209	9.68479586666915e-06	0.000191850103632552	Ups	6	85938605	85978908	+	Gm19265	predicted gene%2C 19265 [Source:MGI Symbol%3BAcc:MGI:5011450]	-	-	-	-	-
ENSMUSG00000053310	1453	437	15.61	239	9.36	158	5.00	107	4.39	228.893835947084	0.407124392129625	-1.29645843432754	0.293062026746682	-4.4238363076912	9.69634996186433e-06	0.000191850103632552	Down	9	37455788	37464200	-	Nrgn	neurogranin [Source:MGI Symbol%3BAcc:MGI:1927184]	GO:0008306:associative learning;GO:0035556:intracellular signal transduction;GO:1900273:positive regulation of long-term synaptic potentiation;GO:0021537:telencephalon development;	GO:0030424:axon;GO:0005737:cytoplasm;GO:0030425:dendrite;GO:0044327:dendritic spine head;GO:0031966:mitochondrial membrane;GO:0043025:neuronal cell body;GO:0005634:nucleus;GO:0098794:postsynapse;GO:0014069:postsynaptic density;GO:0045211:postsynaptic membrane;GO:0045202:synapse;GO:0012510:trans-Golgi network transport vesicle membrane;	GO:0005516:calmodulin binding;GO:0070300:phosphatidic acid binding;GO:0005547:phosphatidylinositol-3,4,5-trisphosphate binding;	-	-
ENSMUSG00000109096	2541	83	1.70	54	1.21	2	0.04	14	0.33	37.420524545575	0.12755843579489	-2.97076978334786	0.672393649594794	-4.41820023900901	9.95261936435715e-06	0.000195842451743366	Down	7	67982737	67985277	+	Gm44888	predicted gene 44888 [Source:MGI Symbol%3BAcc:MGI:5753464]	-	-	-	-	-
ENSMUSG00000063171	1334	41	1.60	55	2.35	146	5.04	115	5.13	89.0471686332728	2.81157665977107	1.49137938359001	0.337590303030694	4.41771985214402	9.97475901992753e-06	0.000195842451743366	Ups	6	148256098	148257431	+	Rps4l	ribosomal protein S4-like [Source:MGI Symbol%3BAcc:MGI:1913434]	GO:0006412:translation;	GO:0022627:cytosolic small ribosomal subunit;	GO:0003723:RNA binding;GO:0019843:rRNA binding;GO:0003735:structural constituent of ribosome;	K02987	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000035914	3658	156	2.21	73	1.14	35	0.44	8	0.13	65.28921936782	0.189747183066756	-2.39784962693193	0.543306451576639	-4.41343852990062	1.01741615276031e-05	0.000198739608744287	Down	9	58431581	58462720	-	Cd276	CD276 antigen [Source:MGI Symbol%3BAcc:MGI:2183926]	GO:0050728:negative regulation of inflammatory response;GO:0032689:negative regulation of interferon-gamma production;GO:0032703:negative regulation of interleukin-2 production;GO:0042130:negative regulation of T cell proliferation;GO:0030501:positive regulation of bone mineralization;GO:0032729:positive regulation of interferon-gamma production;GO:0032743:positive regulation of interleukin-2 production;GO:0045669:positive regulation of osteoblast differentiation;GO:0042102:positive regulation of T cell proliferation;GO:0001817:regulation of cytokine production;GO:0050776:regulation of immune response;GO:0042110:T cell activation;GO:0050852:T cell receptor signaling pathway;	GO:0009897:external side of plasma membrane;GO:0016021:integral component of membrane;	GO:0042802:identical protein binding;GO:0005102:receptor binding;	K06746	;ko04514 Cell adhesion molecules;
ENSMUSG00000070639	6726	298	2.30	229	1.94	98	0.67	118	1.04	182.895375299203	0.433141733541559	-1.20708891100007	0.274257753009592	-4.40129366537127	1.07607367316593e-05	0.000209663452405672	Down	5	105563641	105637940	+	Lrrc8b	leucine rich repeat containing 8 family%2C member B [Source:MGI Symbol%3BAcc:MGI:2141353]	GO:0098656:anion transmembrane transport;	GO:0005737:cytoplasm;GO:0005789:endoplasmic reticulum membrane;GO:0005887:integral component of plasma membrane;GO:0034702:ion channel complex;GO:0005886:plasma membrane;	GO:0005225:volume-sensitive anion channel activity;	-	-
ENSMUSG00000055003	4102	78	0.99	61	0.85	19	0.21	11	0.16	41.057747535889	0.222862932661131	-2.16577141239893	0.492403722460797	-4.39836523082206	1.09069321452066e-05	0.000212242255729186	Down	6	119292094	119307727	-	Lrtm2	leucine-rich repeats and transmembrane domains 2 [Source:MGI Symbol%3BAcc:MGI:2141485]	GO:0007411:axon guidance;GO:0050919:negative chemotaxis;GO:0051965:positive regulation of synapse assembly;	GO:0016021:integral component of membrane;	GO:0008201:heparin binding;GO:0048495:Roundabout binding;	-	-
ENSMUSG00000025602	3877	208	2.79	147	2.16	379	4.50	303	4.65	257.415455695347	2.000669260338	1.00048268852878	0.228202866820374	4.38418106866418	1.16422909353247e-05	0.000224557093336187	Ups	9	40103612	40124900	+	Zfp202	zinc finger protein 202 [Source:MGI Symbol%3BAcc:MGI:1933401]	GO:0006629:lipid metabolic process;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005694:chromosome;GO:0016604:nuclear body;GO:0005730:nucleolus;	GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001227:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0046872:metal ion binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K09229	-
ENSMUSG00000116632	1497	67	2.32	85	3.23	203	6.24	153	6.09	126.372265101825	2.41849546517167	1.27410983264403	0.290713589973837	4.38269787373439	1.17218618452967e-05	0.000225719639045825	Ups	16	21150643	21152139	-	Magef1	MAGE family member F1 [Source:MGI Symbol%3BAcc:MGI:1923472]	GO:2000042:negative regulation of double-strand break repair via homologous recombination;GO:2000060:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0097428:protein maturation by iron-sulfur cluster transfer;GO:0016567:protein ubiquitination;	-	-	-	-
ENSMUSG00000020668	7406	157	1.10	217	1.67	68	0.42	70	0.56	126.352869481701	0.384729298768193	-1.37808439372165	0.314654058538921	-4.37968097446671	1.1885318082461e-05	0.000227811834345571	Down	12	3415132	3456494	+	Kif3c	kinesin family member 3C [Source:MGI Symbol%3BAcc:MGI:107979]	GO:0007018:microtubule-based movement;GO:0072384:organelle transport along microtubule;GO:0010976:positive regulation of neuron projection development;	GO:0030424:axon;GO:0005829:cytosol;GO:0030425:dendrite;GO:0030426:growth cone;GO:0005871:kinesin complex;GO:0016020:membrane;GO:0005874:microtubule;GO:0015630:microtubule cytoskeleton;GO:0035371:microtubule plus-end;GO:0043025:neuronal cell body;GO:0071598:neuronal ribonucleoprotein granule;GO:0008021:synaptic vesicle;	GO:0005524:ATP binding;GO:0019894:kinesin binding;GO:0008017:microtubule binding;GO:0003777:microtubule motor activity;	K10394	;ko04340 Hedgehog signaling pathway;
ENSMUSG00000078945	4846	258	2.76	221	2.60	102	0.97	107	1.32	169.313485561322	0.457924776205945	-1.1268174701632	0.257652830032703	-4.37339450150879	1.22329374076924e-05	0.000233018462372119	Down	13	100280571	100338600	-	Naip2	NLR family%2C apoptosis inhibitory protein 2 [Source:MGI Symbol%3BAcc:MGI:1298226]	GO:0071391:cellular response to estrogen stimulus;GO:0042742:defense response to bacterium;GO:0016045:detection of bacterium;GO:0006954:inflammatory response;GO:0045087:innate immune response;GO:0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0070269:pyroptosis;	GO:0072557:IPAF inflammasome complex;	GO:0005524:ATP binding;GO:0043027:cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0046872:metal ion binding;	K12807	;ko04621 NOD-like receptor signaling pathway;ko05130 Pathogenic Escherichia coli infection;ko05131 Shigellosis;ko05132 Salmonella infection;ko05134 Legionellosis;
ENSMUSG00000019767	3792	75	1.03	85	1.28	10	0.12	22	0.35	47.3419426815082	0.213051991484091	-2.23072255784767	0.510222339893275	-4.3720597540168	1.23079826687954e-05	0.000234157079706339	Down	10	4432502	4512231	+	Ccdc170	coiled-coil domain containing 170 [Source:MGI Symbol%3BAcc:MGI:2685067]	GO:0000226:microtubule cytoskeleton organization;	GO:0036064:ciliary basal body;GO:0005794:Golgi apparatus;	GO:0008017:microtubule binding;	-	-
ENSMUSG00000037370	10257	264	1.34	215	1.19	125	0.56	90	0.52	169.771956963737	0.465197926432781	-1.10408342871211	0.253027615192929	-4.36348984228564	1.28003886854104e-05	0.000242023625280004	Down	10	24513812	24588057	-	Enpp1	ectonucleotide pyrophosphatase/phosphodiesterase 1 [Source:MGI Symbol%3BAcc:MGI:97370]	GO:0050427:3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0046034:ATP metabolic process;GO:0031214:biomineral tissue development;GO:0046849:bone remodeling;GO:0030643:cellular phosphate ion homeostasis;GO:0032869:cellular response to insulin stimulus;GO:0006091:generation of precursor metabolites and energy;GO:0006955:immune response;GO:0030505:inorganic diphosphate transport;GO:0030318:melanocyte differentiation;GO:0030502:negative regulation of bone mineralization;GO:0030308:negative regulation of cell growth;GO:0045599:negative regulation of fat cell differentiation;GO:0046325:negative regulation of glucose import;GO:0045719:negative regulation of glycogen biosynthetic process;GO:0046627:negative regulation of insulin receptor signaling pathway;GO:0030279:negative regulation of ossification;GO:0031953:negative regulation of protein autophosphorylation;GO:0090305:nucleic acid phosphodiester bond hydrolysis;GO:0009143:nucleoside triphosphate catabolic process;GO:0006796:phosphate-containing compound metabolic process;GO:0030500:regulation of bone mineralization;GO:0030730:sequestering of triglyceride;	GO:0097440:apical dendrite;GO:0097441:basilar dendrite;GO:0016323:basolateral plasma membrane;GO:0044297:cell body;GO:0042995:cell projection;GO:0009986:cell surface;GO:0005615:extracellular space;GO:0016021:integral component of membrane;GO:0005887:integral component of plasma membrane;GO:0043005:neuron projection;GO:0043025:neuronal cell body;GO:0005886:plasma membrane;GO:0045202:synapse;	GO:0005524:ATP binding;GO:0005509:calcium ion binding;GO:0036218:dTTP diphosphatase activity;GO:0004527:exonuclease activity;GO:0042802:identical protein binding;GO:0005158:insulin receptor binding;GO:0035529:NADH pyrophosphatase activity;GO:0003676:nucleic acid binding;GO:0047429:nucleoside-triphosphate diphosphatase activity;GO:0004551:nucleotide diphosphatase activity;GO:0004528:phosphodiesterase I activity;GO:0030247:polysaccharide binding;GO:0042803:protein homodimerization activity;GO:0005044:scavenger receptor activity;GO:0008270:zinc ion binding;	K01513	;ko00230 Purine metabolism;ko00240 Pyrimidine metabolism;ko00500 Starch and sucrose metabolism;ko00740 Riboflavin metabolism;ko00760 Nicotinate and nicotinamide metabolism;ko00770 Pantothenate and CoA biosynthesis;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;
ENSMUSG00000110206	3878	283	3.79	266	3.90	156	1.85	100	1.54	196.896968693182	0.480427668365409	-1.05760885503426	0.242731355448356	-4.3571167518952	1.31786978534818e-05	0.000248258173077752	Down	7	44779212	44785856	-	Flt3l	FMS-like tyrosine kinase 3 ligand [Source:MGI Symbol%3BAcc:MGI:95560]	GO:0035162:embryonic hemopoiesis;GO:0048873:homeostasis of number of cells within a tissue;GO:0030098:lymphocyte differentiation;GO:0071866:negative regulation of apoptotic process in bone marrow;GO:0045787:positive regulation of cell cycle;GO:0008284:positive regulation of cell proliferation;GO:0071864:positive regulation of cell proliferation in bone marrow;GO:0045663:positive regulation of myoblast differentiation;GO:1901741:positive regulation of myoblast fusion;GO:0032825:positive regulation of natural killer cell differentiation;GO:0090290:positive regulation of osteoclast proliferation;GO:0001934:positive regulation of protein phosphorylation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0030885:regulation of myeloid dendritic cell activation;	GO:0009986:cell surface;GO:0005576:extracellular region;GO:0005615:extracellular space;GO:0016021:integral component of membrane;GO:0031233:intrinsic component of external side of plasma membrane;	GO:0005125:cytokine activity;GO:0030971:receptor tyrosine kinase binding;	K05454	;ko04010 MAPK signaling pathway;ko04014 Ras signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04640 Hematopoietic cell lineage;ko05200 Pathways in cancer;
ENSMUSG00000021823	8191	495	3.14	412	2.86	186	1.04	232	1.69	327.074021832934	0.487883805301214	-1.03539049930408	0.238124898249211	-4.34809844294604	1.37322967472429e-05	0.000257421807239881	Down	14	20979466	21083744	+	Vcl	vinculin [Source:MGI Symbol%3BAcc:MGI:98927]	GO:0034333:adherens junction assembly;GO:0043297:apical junction assembly;GO:0048675:axon extension;GO:0007155:cell adhesion;GO:0090136:epithelial cell-cell adhesion;GO:0030032:lamellipodium assembly;GO:0002009:morphogenesis of an epithelium;GO:0034394:protein localization to cell surface;GO:0030334:regulation of cell migration;GO:1903140:regulation of establishment of endothelial barrier;GO:0051893:regulation of focal adhesion assembly;GO:0007160:cell-matrix adhesion;GO:0035633:maintenance of blood-brain barrier;GO:0030336:negative regulation of cell migration;GO:0070527:platelet aggregation;	GO:0015629:actin cytoskeleton;GO:0005912:adherens junction;GO:0005903:brush border;GO:0044291:cell-cell contact zone;GO:0005911:cell-cell junction;GO:0043034:costamere;GO:0005737:cytoplasm;GO:0005916:fascia adherens;GO:0005925:focal adhesion;GO:0090637:inner dense plaque of desmosome;GO:0014704:intercalated disc;GO:0045121:membrane raft;GO:0090636:outer dense plaque of desmosome;GO:0005886:plasma membrane;GO:0002102:podosome;GO:0032991:macromolecular complex;GO:0042383:sarcolemma;GO:1990357:terminal web;GO:0030018:Z disc;GO:0005915:zonula adherens;GO:0030055:cell-substrate junction;GO:0005856:cytoskeleton;GO:0005829:cytosol;GO:0070062:extracellular exosome;GO:0005576:extracellular region;GO:1903561:extracellular vesicle;GO:0034774:secretory granule lumen;GO:0035580:specific granule lumen;	GO:0051015:actin filament binding;GO:0045294:alpha-catenin binding;GO:0002162:dystroglycan binding;GO:0031267:small GTPase binding;GO:0005198:structural molecule activity;GO:0031625:ubiquitin protein ligase binding;GO:0003779:actin binding;GO:0008013:beta-catenin binding;GO:0045296:cadherin binding;	K05700	;ko04510 Focal adhesion;ko04520 Adherens junction;ko04670 Leukocyte transendothelial migration;ko04810 Regulation of actin cytoskeleton;ko05100 Bacterial invasion of epithelial cells;ko05131 Shigellosis;ko05146 Amoebiasis;
ENSMUSG00000100455	3666	98	1.39	104	1.61	211	2.65	218	3.54	158.406506990394	2.22552065689542	1.15414289169662	0.265589963766953	4.34558172051013	1.38907044353575e-05	0.000259439782961963	Ups	1	143653380	143657045	+	Gm29170	predicted gene 29170 [Source:MGI Symbol%3BAcc:MGI:5579876]	-	-	-	-	-
ENSMUSG00000029047	3298	174	2.74	196	3.38	468	6.53	278	5.02	275.101076529634	2.06245809824527	1.04436480926496	0.240371316303778	4.34479797891153	1.39403895975628e-05	0.000260051014706847	Ups	4	155151473	155156890	+	Pex10	peroxisomal biogenesis factor 10 [Source:MGI Symbol%3BAcc:MGI:2684988]	GO:0007031:peroxisome organization;GO:0016558:protein import into peroxisome matrix;	GO:0005779:integral component of peroxisomal membrane;GO:0005778:peroxisomal membrane;GO:0005777:peroxisome;	GO:0046872:metal ion binding;GO:0008022:protein C-terminus binding;	K13346	;ko04146 Peroxisome;
ENSMUSG00000052369	2434	288	6.14	298	6.97	131	2.48	140	3.43	211.481863390116	0.484728058679057	-1.04475249898197	0.240542563660787	-4.3433165552159	1.40347675651403e-05	0.000261493470041144	Down	15	97862081	97868156	+	Tmem106c	transmembrane protein 106C [Source:MGI Symbol%3BAcc:MGI:1196384]	-	GO:0005789:endoplasmic reticulum membrane;GO:0016021:integral component of membrane;	-	-	-
ENSMUSG00000111212	4233	3	0.04	5	0.07	28	0.30	53	0.75	23.1830567746175	10.8538300795146	3.4401323229644	0.792590784842231	4.3403637649524	1.42247037749808e-05	0.000264630989139584	Ups	9	13308563	13312795	+	5330432J10Rik	RIKEN cDNA 5330432J10 gene [Source:MGI Symbol%3BAcc:MGI:2443489]	-	-	-	-	-
ENSMUSG00000019734	4280	198	2.40	211	2.81	106	1.14	66	0.92	142.141970282149	0.43235308195651	-1.20971812154015	0.278726398611015	-4.34016342753528	1.42376787557165e-05	0.000264630989139584	Down	7	3668789	3680552	-	Tmc4	transmembrane channel-like gene family 4 [Source:MGI Symbol%3BAcc:MGI:2669035]	-	GO:0005887:integral component of plasma membrane;	GO:0008381:mechanically-gated ion channel activity;	-	-
ENSMUSG00000092216	993	304	15.89	246	14.10	107	4.96	128	7.68	193.412748817793	0.45115838915003	-1.14829408241487	0.26484025023697	-4.33579896328981	1.45231634348705e-05	0.00026856745265196	Down	7	19585928	19592275	+	Gm19345	predicted gene%2C 19345 [Source:MGI Symbol%3BAcc:MGI:5011530]	GO:0007605:sensory perception of sound;	GO:0005615:extracellular space;GO:0032426:stereocilium bundle tip;	GO:0042802:identical protein binding;	K06499	-
ENSMUSG00000039031	6602	155	1.22	178	1.53	62	0.43	65	0.59	113.373213006453	0.398660281612767	-1.32676821760495	0.306010956043019	-4.33568861311763	1.45304518457066e-05	0.00026856745265196	Down	10	26629417	26794644	+	Arhgap18	Rho GTPase activating protein 18 [Source:MGI Symbol%3BAcc:MGI:1921160]	GO:0032956:regulation of actin cytoskeleton organization;GO:0030833:regulation of actin filament polymerization;GO:2000145:regulation of cell motility;GO:0008360:regulation of cell shape;GO:0051056:regulation of small GTPase mediated signal transduction;GO:0007264:small GTPase mediated signal transduction;	GO:0005737:cytoplasm;GO:0005881:cytoplasmic microtubule;GO:0005829:cytosol;GO:0016607:nuclear speck;GO:0005886:plasma membrane;GO:0001726:ruffle;	GO:0005096:GTPase activator activity;	-	-
ENSMUSG00000025780	7900	143	0.94	115	0.83	56	0.33	29	0.22	83.3926935458948	0.338204894391664	-1.56403055677315	0.361591859344432	-4.32540312054798	1.52253172214336e-05	0.000277934540801742	Down	2	10158382	10261340	+	Itih5	inter-alpha (globulin) inhibitor H5 [Source:MGI Symbol%3BAcc:MGI:1925751]	GO:0030212:hyaluronan metabolic process;	GO:0005576:extracellular region;	GO:0004867:serine-type endopeptidase inhibitor activity;	-	-
ENSMUSG00000101751	881	86	5.07	72	4.65	15	0.78	22	1.49	47.8409288265283	0.247638582133375	-2.01369199068992	0.465903725491816	-4.32212038777805	1.54536822918043e-05	0.000281099364486984	Down	1	85428811	85442325	+	Gm2427	predicted gene 2427 [Source:MGI Symbol%3BAcc:MGI:3780593]	GO:0006952:defense response;GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0001650:fibrillar center;GO:0005739:mitochondrion;GO:0005634:nucleus;GO:0016605:PML body;	GO:0003677:DNA binding;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046872:metal ion binding;	-	-
ENSMUSG00000095332	2034	375	9.57	397	11.11	158	3.57	195	5.71	278.265632953233	0.482176009774972	-1.05236822212957	0.243602627334702	-4.3200199999635	1.56015060357505e-05	0.000283116560416802	Down	2	91776048	91779033	+	Gm9821	predicted gene 9821 [Source:MGI Symbol%3BAcc:MGI:3704208]	-	-	-	-	-
ENSMUSG00000034799	12623	178	0.73	214	0.96	81	0.30	79	0.37	136.056695176971	0.425474723129968	-1.23285466896495	0.285521878928197	-4.31789911719861	1.57521394372358e-05	0.000284838804399262	Down	8	72077061	72124401	-	Unc13a	unc-13 homolog A [Source:MGI Symbol%3BAcc:MGI:3051532]	GO:0030154:cell differentiation;GO:0035556:intracellular signal transduction;GO:0007528:neuromuscular junction development;GO:0007269:neurotransmitter secretion;GO:1903861:positive regulation of dendrite extension;GO:0051966:regulation of synaptic transmission, glutamatergic;GO:0035249:synaptic transmission, glutamatergic;GO:0016081:synaptic vesicle docking;GO:0016188:synaptic vesicle maturation;GO:0016082:synaptic vesicle priming;GO:0050435:beta-amyloid metabolic process;GO:0060384:innervation;GO:0060291:long-term synaptic potentiation;GO:1900451:positive regulation of glutamate receptor signaling pathway;GO:0001956:positive regulation of neurotransmitter secretion;GO:0031915:positive regulation of synaptic plasticity;GO:1902991:regulation of amyloid precursor protein catabolic process;GO:0048172:regulation of short-term neuronal synaptic plasticity;GO:0010807:regulation of synaptic vesicle priming;GO:0016079:synaptic vesicle exocytosis;	GO:0031594:neuromuscular junction;GO:0043005:neuron projection;GO:0005886:plasma membrane;GO:0048786:presynaptic active zone;GO:0042734:presynaptic membrane;GO:0030672:synaptic vesicle membrane;GO:0043195:terminal bouton;GO:0030424:axon;GO:0044305:calyx of Held;GO:0060076:excitatory synapse;GO:0005798:Golgi-associated vesicle;GO:0098793:presynapse;GO:0032991:macromolecular complex;GO:0045202:synapse;GO:0097060:synaptic membrane;	GO:0005509:calcium ion binding;GO:0005516:calmodulin binding;GO:0019992:diacylglycerol binding;GO:0005543:phospholipid binding;GO:0017075:syntaxin-1 binding;GO:0042802:identical protein binding;GO:0019904:protein domain specific binding;GO:0047485:protein N-terminus binding;GO:0044877:macromolecular complex binding;GO:0000149:SNARE binding;GO:0030507:spectrin binding;GO:0019905:syntaxin binding;	K15293	;ko04721 Synaptic vesicle cycle;
ENSMUSG00000025350	2809	65	1.20	74	1.50	19	0.31	13	0.28	41.7943268709651	0.237631968657433	-2.07319915975428	0.480195157612885	-4.31740955085934	1.57871067815295e-05	0.000285134859114221	Down	10	128749462	128758757	-	Rdh5	retinol dehydrogenase 5 [Source:MGI Symbol%3BAcc:MGI:1201412]	GO:0050896:response to stimulus;GO:0001523:retinoid metabolic process;GO:0042572:retinol metabolic process;GO:0008202:steroid metabolic process;GO:0007601:visual perception;GO:0009060:aerobic respiration;GO:0008089:anterograde axon cargo transport;GO:0048490:anterograde synaptic vesicle transport;GO:0016197:endosomal transport;GO:0032418:lysosome localization;GO:0031175:neuron projection development;GO:0018394:peptidyl-lysine acetylation;	GO:0044297:cell body;GO:0005788:endoplasmic reticulum lumen;GO:0005789:endoplasmic reticulum membrane;GO:0016021:integral component of membrane;GO:1904115:axon cytoplasm;GO:0031083:BLOC-1 complex;GO:0005829:cytosol;GO:0005769:early endosome;GO:0005765:lysosomal membrane;GO:0005758:mitochondrial intermembrane space;GO:0005759:mitochondrial matrix;GO:0005739:mitochondrion;	GO:0047044:androstan-3-alpha,17-beta-diol dehydrogenase activity;GO:0047023:androsterone dehydrogenase activity;GO:0004745:retinol dehydrogenase activity;GO:0042803:protein homodimerization activity;	K00061	;ko00830 Retinol metabolism;
ENSMUSG00000031312	1799	47	1.36	48	1.52	125	3.20	121	4.01	85.563887890889	2.70704678463079	1.43671982119587	0.333393635243612	4.30937987207241	1.63712954881705e-05	0.000292925840158233	Ups	X	100492694	100497147	+	Itgb1bp2	integrin beta 1 binding protein 2 [Source:MGI Symbol%3BAcc:MGI:1353420]	-	GO:0030018:Z disc;	GO:0005509:calcium ion binding;GO:0005178:integrin binding;GO:0017124:SH3 domain binding;GO:0008270:zinc ion binding;	K16735	-
ENSMUSG00000033060	11951	517	2.25	558	2.66	194	0.75	277	1.38	383.099657167237	0.465179435796935	-1.10414077393508	0.256544847741974	-4.30388987989187	1.67825104483069e-05	0.000298888519412704	Down	14	101967393	102172146	+	Lmo7	LIM domain only 7 [Source:MGI Symbol%3BAcc:MGI:1353586]	GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0016567:protein ubiquitination;GO:0030155:regulation of cell adhesion;GO:0023051:regulation of signaling;	GO:0016324:apical plasma membrane;GO:0009986:cell surface;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005925:focal adhesion;GO:0005635:nuclear envelope;GO:0005634:nucleus;GO:0000151:ubiquitin ligase complex;	GO:0046872:metal ion binding;GO:0004842:ubiquitin-protein transferase activity;	K06084	;ko04520 Adherens junction;
ENSMUSG00000021253	3383	70	1.07	61	1.03	15	0.20	14	0.25	39.0889721353016	0.231035383254213	-2.11381427642256	0.492033455869136	-4.29607834834866	1.7384616157673e-05	0.00030818000481128	Down	12	86103519	86125815	-	Tgfb3	transforming growth factor%2C beta 3 [Source:MGI Symbol%3BAcc:MGI:98727]	GO:0000187:activation of MAPK activity;GO:0007568:aging;GO:0009887:organ morphogenesis;GO:0030509:BMP signaling pathway;	GO:0009986:cell surface;GO:0005737:cytoplasm;GO:0031012:extracellular matrix;	GO:0005125:cytokine activity;GO:0008083:growth factor activity;GO:0042802:identical protein binding;GO:0044877:macromolecular complex binding;	K13377	;ko04010 MAPK signaling pathway;ko04060 Cytokine-cytokine receptor interaction;ko04068 FoxO signaling pathway;ko04110 Cell cycle;ko04218 Cellular senescence;ko04350 TGF-beta signaling pathway;ko04390 Hippo signaling pathway;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05140 Leishmaniasis;ko05142 Chagas disease;ko05144 Malaria;ko05145 Toxoplasmosis;ko05146 Amoebiasis;ko05152 Tuberculosis;ko05161 Hepatitis B;ko05166 Human T-cell leukemia virus 1 infection;ko05200 Pathways in cancer;ko05210 Colorectal cancer;ko05211 Renal cell carcinoma;ko05212 Pancreatic cancer;ko05220 Chronic myeloid leukemia;ko05225 Hepatocellular carcinoma;ko05226 Gastric cancer;ko05321 Inflammatory bowel disease;ko05323 Rheumatoid arthritis;ko05410 Hypertrophic cardiomyopathy;ko05414 Dilated cardiomyopathy;
ENSMUSG00000016128	8594	61	0.37	65	0.43	159	0.85	137	0.95	105.388081374901	2.44337849360396	1.28887736280698	0.300059362734947	4.29540791881735	1.74372404748587e-05	0.000308755941618341	Ups	5	150960975	151157301	-	Stard13	StAR-related lipid transfer (START) domain containing 13 [Source:MGI Symbol%3BAcc:MGI:2385331]	GO:0030036:actin cytoskeleton organization;GO:0007049:cell cycle;GO:0043542:endothelial cell migration;GO:0097498:endothelial tube lumen extension;GO:0090051:negative regulation of cell migration involved in sprouting angiogenesis;GO:1903671:negative regulation of sprouting angiogenesis;GO:0035023:regulation of Rho protein signal transduction;GO:0007165:signal transduction;	GO:0005811:lipid particle;GO:0031966:mitochondrial membrane;GO:0005737:cytoplasm;GO:0005925:focal adhesion;GO:0016020:membrane;	GO:0005096:GTPase activator activity;GO:0008289:lipid binding;	-	-
ENSMUSG00000048001	1363	31	1.18	24	1.00	116	3.92	68	2.97	58.9391383153534	3.43622481113987	1.78082442626299	0.414914275986758	4.29202977416911	1.77047200925286e-05	0.000312703364793985	Ups	4	155045380	155046828	+	Hes5	hes family bHLH transcription factor 5 [Source:MGI Symbol%3BAcc:MGI:104876]	GO:0009952:anterior/posterior pattern specification;GO:0048708:astrocyte differentiation;GO:0007420:brain development;GO:0043010:camera-type eye development;GO:0051216:cartilage development;GO:0007155:cell adhesion;GO:0048469:cell maturation;GO:0022010:central nervous system myelination;GO:0072049:comma-shaped body morphogenesis;GO:0090162:establishment of epithelial cell polarity;GO:0021861:forebrain radial glial cell differentiation;GO:0021781:glial cell fate commitment;GO:0060122:inner ear receptor stereocilium organization;GO:0072282:metanephric nephron tubule morphogenesis;GO:0048712:negative regulation of astrocyte differentiation;GO:2000978:negative regulation of forebrain neuron differentiation;GO:0045608:negative regulation of auditory receptor cell differentiation;GO:2000981:negative regulation of inner ear receptor cell differentiation;GO:0045665:negative regulation of neuron differentiation;GO:0048715:negative regulation of oligodendrocyte differentiation;GO:2000974:negative regulation of pro-B cell differentiation;GO:2000737:negative regulation of stem cell differentiation;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0045892:negative regulation of transcription, DNA-templated;GO:0021915:neural tube development;GO:0097150:neuronal stem cell maintenance;GO:0007219:Notch signaling pathway;GO:0014003:oligodendrocyte development;GO:0030513:positive regulation of BMP signaling pathway;GO:0008284:positive regulation of cell proliferation;GO:0045747:positive regulation of Notch signaling pathway;GO:0046427:positive regulation of JAK-STAT cascade;GO:0048661:positive regulation of smooth muscle cell proliferation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-templated;GO:0042531:positive regulation of tyrosine phosphorylation of STAT protein;GO:0065003:macromolecular complex assembly;GO:0045595:regulation of cell differentiation;GO:0050678:regulation of epithelial cell proliferation;GO:0031641:regulation of myelination;GO:0050767:regulation of neurogenesis;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0072050:S-shaped body morphogenesis;GO:0007224:smoothened signaling pathway;GO:0072086:specification of loop of Henle identity;GO:0021537:telencephalon development;	GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0003682:chromatin binding;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001227:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003690:double-stranded DNA binding;GO:0046983:protein dimerization activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K06055	;ko04330 Notch signaling pathway;ko05165 Human papillomavirus infection;ko05200 Pathways in cancer;ko05224 Breast cancer;
ENSMUSG00000060019	342	228	34.61	200	33.28	594	79.92	302	52.59	324.490638760135	2.13281866354087	1.09276131010819	0.254756521592684	4.289434096825	1.7912895561164e-05	0.000315719931649297	Ups	8	107299641	107299982	-	Gm10073	predicted pseudogene 10073 [Source:MGI Symbol%3BAcc:MGI:3641908]	GO:0002181:cytoplasmic translation;GO:0006417:regulation of translation;GO:0006414:translational elongation;	GO:0005829:cytosol;GO:0022625:cytosolic large ribosomal subunit;	GO:0030295:protein kinase activator activity;GO:0043021:ribonucleoprotein complex binding;GO:0003735:structural constituent of ribosome;	K02942	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000016239	3812	1	0.01	1	0.01	33	0.40	33	0.52	17.2798777871023	34.5704981483394	5.11146948734972	1.19243262523385	4.28658976547819	1.81436905720929e-05	0.00031942060991099	Ups	X	35592006	35625994	+	Lonrf3	LON peptidase N-terminal domain and ring finger 3 [Source:MGI Symbol%3BAcc:MGI:1921615]	-	-	GO:0046872:metal ion binding;	-	-
ENSMUSG00000107577	3662	92	1.30	87	1.35	204	2.56	173	2.81	138.579883224801	2.19165274936502	1.13201923239748	0.264275071129328	4.28348851656729	1.83985598677144e-05	0.000323165540677587	Ups	6	116237395	116241056	-	Gm44103	predicted gene%2C 44103 [Source:MGI Symbol%3BAcc:MGI:5690495]	-	-	-	-	-
ENSMUSG00000050675	2718	17	0.32	11	0.23	91	1.54	43	0.94	39.6695645899183	4.87952101652821	2.28673953692861	0.53479419645316	4.27592436884063	1.90345840271462e-05	0.00033130114809564	Ups	11	70529948	70532862	+	Gp1ba	glycoprotein 1b%2C alpha polypeptide [Source:MGI Symbol%3BAcc:MGI:1333744]	GO:0007596:blood coagulation;GO:0007155:cell adhesion;GO:0000902:cell morphogenesis;GO:0042730:fibrinolysis;GO:0007599:hemostasis;GO:0070527:platelet aggregation;	GO:0031362:anchored component of external side of plasma membrane;GO:0031012:extracellular matrix;GO:0005615:extracellular space;GO:0005887:integral component of plasma membrane;GO:0016020:membrane;GO:0005886:plasma membrane;	-	K06261	;ko04512 ECM-receptor interaction;ko04611 Platelet activation;ko04613 Neutrophil extracellular trap formation;ko04640 Hematopoietic cell lineage;
ENSMUSG00000030301	2870	251	4.54	239	4.74	105	1.68	114	2.37	174.798085700126	0.469074693480484	-1.09211042516631	0.255513575781978	-4.27417769026165	1.91843998629528e-05	0.000333530144556143	Down	6	147377326	147534110	+	Ccdc91	coiled-coil domain containing 91 [Source:MGI Symbol%3BAcc:MGI:1914265]	GO:0090160:Golgi to lysosome transport;GO:0015031:protein transport;	GO:0005829:cytosol;GO:0005794:Golgi apparatus;GO:0016020:membrane;GO:0005654:nucleoplasm;GO:0005802:trans-Golgi network;	-	-	-
ENSMUSG00000040721	18166	149	0.43	203	0.64	67	0.17	66	0.22	119.625671744353	0.393409972763381	-1.34589456514608	0.315622910864306	-4.26424862967158	2.00576004812253e-05	0.000344415728756002	Down	14	55297719	55329781	-	Zfhx2	zinc finger homeobox 2 [Source:MGI Symbol%3BAcc:MGI:2686934]	GO:0030534:adult behavior;GO:0007420:brain development;GO:0045664:regulation of neuron differentiation;GO:0051930:regulation of sensory perception of pain;GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005634:nucleus;	GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0008270:zinc ion binding;	K09379	-
ENSMUSG00000079657	2852	11	0.20	10	0.20	66	1.06	41	0.86	31.7013250293209	5.23844071205567	2.38913743928966	0.560512634569367	4.26241496077103	2.02229466778255e-05	0.000346866514941584	Ups	17	24746215	24753184	-	Rab26	RAB26%2C member RAS oncogene family [Source:MGI Symbol%3BAcc:MGI:2443284]	GO:0035272:exocrine system development;GO:0043001:Golgi to plasma membrane protein transport;GO:0045055:regulated secretory pathway;GO:0017157:regulation of exocytosis;	GO:0005768:endosome;GO:0005794:Golgi apparatus;GO:0000139:Golgi membrane;GO:0031226:intrinsic component of plasma membrane;GO:0030667:secretory granule membrane;	GO:0019002:GMP binding;GO:0005525:GTP binding;GO:0003924:GTPase activity;	K07913	-
ENSMUSG00000102608	681	85	6.48	131	10.95	31	2.09	31	2.71	68.5191209839387	0.298409756561417	-1.7446333893456	0.409599131177747	-4.25936789545706	2.05005815653146e-05	0.000349284353025038	Down	1	180336343	180347292	-	Gm37267	predicted gene%2C 37267 [Source:MGI Symbol%3BAcc:MGI:5610495]	-	-	-	-	-
ENSMUSG00000024777	3372	109	1.68	152	2.57	54	0.74	31	0.55	84.7064980221706	0.333008468653326	-1.58636922831514	0.372495124005665	-4.25876508464313	2.05559352876974e-05	0.000349838747726472	Down	19	6277795	6285902	-	Ppp2r5b	protein phosphatase 2%2C regulatory subunit B'%2C beta [Source:MGI Symbol%3BAcc:MGI:2388480]	GO:0071363:cellular response to growth factor stimulus;GO:0070317:negative regulation of G0 to G1 transition;GO:0051091:positive regulation of sequence-specific DNA binding transcription factor activity;GO:0010976:positive regulation of neuron projection development;GO:0051388:positive regulation of neurotrophin TRK receptor signaling pathway;GO:0031334:positive regulation of protein complex assembly;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0006470:protein dephosphorylation;GO:0051726:regulation of cell cycle;GO:0050730:regulation of peptidyl-tyrosine phosphorylation;GO:0031952:regulation of protein autophosphorylation;GO:0001932:regulation of protein phosphorylation;GO:0010469:regulation of receptor activity;GO:0007165:signal transduction;	GO:0005829:cytosol;GO:0005634:nucleus;GO:0000159:protein phosphatase type 2A complex;	GO:0072542:protein phosphatase activator activity;GO:0019888:protein phosphatase regulator activity;	K11584	;ko03015 mRNA surveillance pathway;ko04071 Sphingolipid signaling pathway;ko04113 Meiosis - yeast;ko04114 Oocyte meiosis;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04261 Adrenergic signaling in cardiomyocytes;ko04728 Dopaminergic synapse;ko05165 Human papillomavirus infection;
ENSMUSG00000120340	1904	13	0.35	12	0.36	64	1.55	49	1.53	34.4454565882386	4.68523307385773	2.22812081867098	0.523254400557468	4.25819795552063	2.06081423998944e-05	0.000350338420798204	Ups	2	91067469	91084494	+	A330069E16Rik	RIKEN cDNA A330069E16 gene [Source:NCBI gene (formerly Entrezgene)%3BAcc:606735]	-	-	-	-	-
ENSMUSG00000031778	3930	94	1.24	81	1.17	243	2.85	150	2.27	140.097249733637	2.30908614902245	1.20732199920512	0.283809699138475	4.25398428196794	2.10000048579296e-05	0.000355423923279793	Ups	8	95498637	95509055	+	Cx3cl1	chemokine (C-X3-C motif) ligand 1 [Source:MGI Symbol%3BAcc:MGI:1097153]	GO:0060055:angiogenesis involved in wound healing;GO:0035425:autocrine signaling;GO:0007155:cell adhesion;GO:0060326:cell chemotaxis;	GO:0044297:cell body;GO:0042995:cell projection;GO:0009986:cell surface;GO:0005737:cytoplasm;	GO:0048020:CCR chemokine receptor binding;GO:0042056:chemoattractant activity;GO:0008009:chemokine activity;GO:0031737:CX3C chemokine receptor binding;	K05508	;ko04060 Cytokine-cytokine receptor interaction;ko04061 Viral protein interaction with cytokine and cytokine receptor;ko04062 Chemokine signaling pathway;ko04668 TNF signaling pathway;ko05163 Human cytomegalovirus infection;
ENSMUSG00000115276	3745	189	2.62	204	3.10	34	0.42	78	1.24	125.075087590436	0.306902008938464	-1.70415000536816	0.400717439200292	-4.25274729437558	2.11163823435304e-05	0.000356214088950159	Down	15	34127090	34130834	+	9930017N22Rik	RIKEN cDNA 9930017N22 gene [Source:MGI Symbol%3BAcc:MGI:2443961]	-	-	-	-	-
ENSMUSG00000086213	2323	93	2.08	101	2.47	34	0.67	26	0.67	62.2125423808663	0.320251474608415	-1.64272288136853	0.386605384645506	-4.24909467537502	2.1463619685783e-05	0.000360880640637934	Down	19	12495279	12573930	-	A330040F15Rik	RIKEN cDNA A330040F15 gene [Source:MGI Symbol%3BAcc:MGI:3698434]	-	-	-	-	-
ENSMUSG00000032372	3180	2	0.03	1	0.02	33	0.48	29	0.54	16.3992925715101	21.5760603444955	4.43135955654676	1.04423019973251	4.24366155822913	2.199019250345e-05	0.000369231559196108	Ups	9	92157655	92179805	+	Plscr2	phospholipid scramblase 2 [Source:MGI Symbol%3BAcc:MGI:1270860]	GO:0071222:cellular response to lipopolysaccharide;GO:0070782:phosphatidylserine exposure on apoptotic cell surface;GO:0017121:phospholipid scrambling;GO:0006953:acute-phase response;GO:0006915:apoptotic process;GO:0051607:defense response to virus;GO:0050765:negative regulation of phagocytosis;GO:0045071:negative regulation of viral genome replication;GO:0006659:phosphatidylserine biosynthetic process;GO:0030168:platelet activation;GO:2000373:positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity;GO:0010628:positive regulation of gene expression;GO:0045089:positive regulation of innate immune response;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0060368:regulation of Fc receptor mediated stimulatory signaling pathway;GO:0033003:regulation of mast cell activation;GO:0035456:response to interferon-beta;GO:0010288:response to lead ion;	GO:0005737:cytoplasm;GO:0016021:integral component of membrane;GO:0005634:nucleus;GO:0005886:plasma membrane;GO:0005829:cytosol;GO:0070062:extracellular exosome;GO:0005794:Golgi apparatus;GO:0005887:integral component of plasma membrane;GO:0016020:membrane;GO:0045121:membrane raft;GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0048471:perinuclear region of cytoplasm;	GO:0046872:metal ion binding;GO:0017128:phospholipid scramblase activity;GO:0017124:SH3 domain binding;GO:0005509:calcium ion binding;GO:0042609:CD4 receptor binding;GO:0003677:DNA binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0019899:enzyme binding;GO:0005154:epidermal growth factor receptor binding;GO:0032791:lead ion binding;GO:0000287:magnesium ion binding;GO:0045340:mercury ion binding;GO:0004518:nuclease activity;GO:0001618:virus receptor activity;GO:0008270:zinc ion binding;	-	-
ENSMUSG00000001911	7351	90	0.64	124	0.96	255	1.60	203	1.64	167.436254312561	2.21250042923379	1.14567773508418	0.271115542026542	4.22579143386779	2.38102448455913e-05	0.000395136682318503	Ups	8	85426505	85526973	-	Nfix	nuclear factor I/X [Source:MGI Symbol%3BAcc:MGI:97311]	GO:0006260:DNA replication;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0006366:transcription from RNA polymerase II promoter;GO:0048708:astrocyte differentiation;GO:0021707:cerebellar granule cell differentiation;GO:0021680:cerebellar Purkinje cell layer development;GO:0021549:cerebellum development;	GO:0005634:nucleus;GO:0000785:chromatin;	GO:0003677:DNA binding;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000977:RNA polymerase II regulatory region sequence-specific DNA binding;	K09171	-
ENSMUSG00000019791	5519	214	2.01	202	2.08	70	0.58	94	1.01	143.211367569597	0.416987443499866	-1.26192415359924	0.299700513623527	-4.21061725367755	2.54673901110418e-05	0.00041856051442949	Down	10	30484137	30505628	-	Hint3	histidine triad nucleotide binding protein 3 [Source:MGI Symbol%3BAcc:MGI:1914097]	-	GO:0005737:cytoplasm;GO:0005634:nucleus;	GO:0043530:adenosine 5'-monophosphoramidase activity;GO:0042802:identical protein binding;GO:0000166:nucleotide binding;	-	-
ENSMUSG00000096959	2481	42	0.88	43	0.99	3	0.06	7	0.17	23.2810524542341	0.124568542030373	-3.00498831213429	0.714406974490813	-4.20626956263419	2.59620543941775e-05	0.00042577769206451	Down	16	10996040	11010156	+	4930509G22Rik	RIKEN cDNA 4930509G22 gene [Source:MGI Symbol%3BAcc:MGI:1914984]	-	-	-	-	-
ENSMUSG00000020644	2438	116	2.47	96	2.24	225	4.25	201	4.91	159.12780740559	2.09828970289147	1.06921387909294	0.25432663555464	4.20409713186814	2.62126362666534e-05	0.000428055979246926	Ups	12	25143798	25147139	-	Id2	inhibitor of DNA binding 2 [Source:MGI Symbol%3BAcc:MGI:96397]	GO:0060612:adipose tissue development;GO:0008344:adult locomotory behavior;GO:0003166:bundle of His development;GO:0048468:cell development;	GO:0000785:chromatin;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0000791:euchromatin;	GO:0046983:protein dimerization activity;GO:0061629:RNA polymerase II sequence-specific DNA binding transcription factor binding;GO:0044325:ion channel binding;	K17693	;ko04350 TGF-beta signaling pathway;ko04390 Hippo signaling pathway;ko04550 Signaling pathways regulating pluripotency of stem cells;ko05202 Transcriptional misregulation in cancer;
ENSMUSG00000037890	11278	141	0.65	140	0.71	52	0.21	54	0.29	95.2189322776719	0.394759984031766	-1.34095234056634	0.319595121216045	-4.19578476499914	2.71928390914861e-05	0.000442179209574599	Down	5	65357039	65417758	+	Wdr19	WD repeat domain 19 [Source:MGI Symbol%3BAcc:MGI:2443231]	GO:0000902:cell morphogenesis;GO:0060830:ciliary receptor clustering involved in smoothened signaling pathway;GO:0060271:cilium morphogenesis;GO:0055123:digestive system development;GO:0042471:ear morphogenesis;GO:0031076:embryonic camera-type eye development;GO:0048701:embryonic cranial skeleton morphogenesis;GO:0030326:embryonic limb morphogenesis;GO:0008406:gonad development;GO:0001701:in utero embryonic development;GO:0035721:intraciliary retrograde transport;GO:0061055:myotome development;GO:0050877:neurological system process;GO:1903441:protein localization to ciliary membrane;GO:0061512:protein localization to cilium;GO:0065003:macromolecular complex assembly;GO:0007224:smoothened signaling pathway;GO:0060831:smoothened signaling pathway involved in dorsal/ventral neural tube patterning;	GO:0005929:cilium;GO:0005737:cytoplasm;GO:0005856:cytoskeleton;GO:0030991:intraciliary transport particle A;GO:0031514:motile cilium;GO:0032391:photoreceptor connecting cilium;GO:0001750:photoreceptor outer segment;	-	K19671	-
ENSMUSG00000097035	688	3	0.23	2	0.17	26	1.74	39	3.38	18.0671514726465	13.8675905836127	3.79364524411857	0.90438788754778	4.19471036305553	2.73220483329627e-05	0.00044333998850545	Ups	5	107807327	107835876	-	Gm26692	predicted gene%2C 26692 [Source:MGI Symbol%3BAcc:MGI:5477186]	-	-	-	-	-
ENSMUSG00000026463	12248	36	0.15	18	0.08	88	0.33	93	0.45	59.1639975883139	3.53988632580062	1.82370303267074	0.435651650274517	4.18614971737527	2.8372623873054e-05	0.000458930184039462	Ups	1	133627195	133728779	-	Atp2b4	ATPase%2C Ca++ transporting%2C plasma membrane 4 [Source:MGI Symbol%3BAcc:MGI:88111]	GO:1901660:calcium ion export;GO:0070588:calcium ion transmembrane transport;GO:0006816:calcium ion transport;GO:0006874:cellular calcium ion homeostasis;GO:0071872:cellular response to epinephrine stimulus;GO:0030317:sperm motility;GO:0021766:hippocampus development;GO:0016525:negative regulation of angiogenesis;GO:1900082:negative regulation of arginine catabolic process;GO:0043537:negative regulation of blood vessel endothelial cell migration;GO:0070885:negative regulation of calcineurin-NFAT signaling cascade;GO:1903243:negative regulation of cardiac muscle hypertrophy in response to stress;GO:1902548:negative regulation of cellular response to vascular endothelial growth factor stimulus;GO:1903249:negative regulation of citrulline biosynthetic process;GO:0010629:negative regulation of gene expression;GO:0045019:negative regulation of nitric oxide biosynthetic process;GO:0010751:negative regulation of nitric oxide mediated signal transduction;GO:0051001:negative regulation of nitric-oxide synthase activity;GO:0098736:negative regulation of the force of heart contraction;GO:0003407:neural retina development;GO:2000481:positive regulation of cAMP-dependent protein kinase activity;GO:0033138:positive regulation of peptidyl-serine phosphorylation;GO:1903078:positive regulation of protein localization to plasma membrane;GO:1902806:regulation of cell cycle G1/S phase transition;GO:0051480:cytosolic calcium ion homeostasis;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0051599:response to hydrostatic pressure;GO:0007283:spermatogenesis;GO:0014832:urinary bladder smooth muscle contraction;	GO:0016323:basolateral plasma membrane;GO:0005887:integral component of plasma membrane;GO:0043231:intracellular membrane-bounded organelle;GO:0016020:membrane;GO:0043005:neuron projection;GO:0005886:plasma membrane;GO:0042383:sarcolemma;GO:0036126:sperm flagellum;GO:0097228:sperm principal piece;GO:0030315:T-tubule;GO:0030018:Z disc;	GO:0005524:ATP binding;GO:0019829:cation-transporting ATPase activity;GO:0015085:calcium ion transmembrane transporter activity;GO:0048306:calcium-dependent protein binding;GO:0005516:calmodulin binding;GO:0046872:metal ion binding;GO:0050998:nitric-oxide synthase binding;GO:0036487:nitric-oxide synthase inhibitor activity;GO:0005388:calcium-transporting ATPase activity;GO:0030165:PDZ domain binding;GO:0019901:protein kinase binding;GO:0030346:protein phosphatase 2B binding;	K05850	;ko04020 Calcium signaling pathway;ko04022 cGMP-PKG signaling pathway;ko04024 cAMP signaling pathway;ko04261 Adrenergic signaling in cardiomyocytes;ko04925 Aldosterone synthesis and secretion;ko04961 Endocrine and other factor-regulated calcium reabsorption;ko04970 Salivary secretion;ko04972 Pancreatic secretion;ko04978 Mineral absorption;
ENSMUSG00000051000	5290	122	1.20	69	0.74	356	3.10	160	1.80	172.466175426045	2.75198738127988	1.46047385484863	0.349090325249477	4.18365606037608	2.86858006133408e-05	0.000463290097540743	Ups	3	85567368	85724598	-	Fhip1a	FHF complex subunit HOOK interacting protein 1A [Source:MGI Symbol%3BAcc:MGI:2444746]	-	-	-	-	-
ENSMUSG00000114535	2354	6	0.13	7	0.17	38	0.74	46	1.16	24.7341275576115	6.81270154416229	2.76822700550536	0.66257284092169	4.17799649266417	2.94088189145911e-05	0.000473194993952088	Ups	13	59751123	59753476	+	Gm47246	predicted gene%2C 47246 [Source:MGI Symbol%3BAcc:MGI:6096070]	-	-	-	-	-
ENSMUSG00000026482	6907	256	1.92	239	1.97	139	0.93	98	0.85	179.32520455422	0.495045423768526	-1.01436718658609	0.242846475355185	-4.17698953671238	2.95392608028973e-05	0.000474298455656154	Down	1	152392511	152642102	-	Rgl1	ral guanine nucleotide dissociation stimulator%2C-like 1 [Source:MGI Symbol%3BAcc:MGI:107484]	GO:0007264:small GTPase mediated signal transduction;	-	GO:0005085:guanyl-nucleotide exchange factor activity;	K17635	;ko04014 Ras signaling pathway;
ENSMUSG00000111897	251	101	20.89	103	23.35	262	48.03	168	39.86	156.629371328391	2.16693664160382	1.11565697153022	0.267437752343129	4.17165101693946	3.0240053585944e-05	0.000483525528349181	Ups	10	79724546	79724796	+	Gm19810	predicted gene%2C 19810 [Source:MGI Symbol%3BAcc:MGI:5011995]	GO:0002181:cytoplasmic translation;GO:0000447:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000461:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);	GO:0005829:cytosol;GO:0022626:cytosolic ribosome;GO:0022627:cytosolic small ribosomal subunit;GO:0042788:polysomal ribosome;GO:0005791:rough endoplasmic reticulum;GO:0045202:synapse;	GO:0047485:protein N-terminus binding;GO:0043022:ribosome binding;GO:0003735:structural constituent of ribosome;	K02971	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000041625	5462	133	1.26	113	1.18	315	2.65	192	2.09	185.551268810514	2.1180795454443	1.08275677141857	0.259944713175265	4.16533484444646	3.10895920143456e-05	0.000494530916958481	Ups	14	123053635	123151169	-	Ggact	gamma-glutamylamine cyclotransferase [Source:MGI Symbol%3BAcc:MGI:2385008]	GO:0042219:cellular modified amino acid catabolic process;	GO:0005829:cytosol;	-	-	-
ENSMUSG00000120789	1087	128	6.11	162	8.48	33	1.40	56	3.07	93.835283096407	0.325808160333965	-1.61790535619917	0.388648225469264	-4.16290426708025	3.14225133452357e-05	0.000498791738753462	Down	X	162741746	162756067	+	-	novel transcript	-	-	-	-	-
ENSMUSG00000031788	5298	69	0.68	50	0.54	135	1.17	159	1.79	104.156232223479	2.61337493273502	1.38591411845588	0.33406131220033	4.14868189712665	3.34395089013296e-05	0.000525370317103471	Ups	8	95826456	95929440	-	Kifc3	kinesin family member C3 [Source:MGI Symbol%3BAcc:MGI:109202]	GO:0090136:epithelial cell-cell adhesion;GO:0007030:Golgi organization;GO:0007018:microtubule-based movement;GO:0007017:microtubule-based process;GO:0045218:zonula adherens maintenance;	GO:0005813:centrosome;GO:0030659:cytoplasmic vesicle membrane;GO:0005794:Golgi apparatus;GO:0005871:kinesin complex;GO:0005874:microtubule;GO:0005915:zonula adherens;	GO:0005524:ATP binding;GO:0008569:ATP-dependent microtubule motor activity, minus-end-directed;GO:0042802:identical protein binding;GO:0008017:microtubule binding;	K10406	-
ENSMUSG00000040631	3054	32	0.54	45	0.84	174	2.62	77	1.50	80.2572026506242	3.28969941158399	1.71795576717367	0.415144130220213	4.13821524168578	3.50017934971063e-05	0.000547260590970824	Ups	8	95590456	95602958	-	Dok4	docking protein 4 [Source:MGI Symbol%3BAcc:MGI:2148865]	GO:0007399:nervous system development;GO:0043410:positive regulation of MAPK cascade;GO:0007169:transmembrane receptor protein tyrosine kinase signaling pathway;	-	-	-	-
ENSMUSG00000074575	4508	22	0.25	39	0.49	105	1.07	88	1.16	63.614364607891	3.27245521804592	1.71037344972739	0.413655222481827	4.13478026329652	3.55294423081822e-05	0.000553667142635839	Ups	2	168102037	168123656	-	Kcng1	potassium voltage-gated channel%2C subfamily G%2C member 1 [Source:MGI Symbol%3BAcc:MGI:3616086]	GO:0071805:potassium ion transmembrane transport;GO:0006813:potassium ion transport;GO:0051260:protein homooligomerization;GO:1902259:regulation of delayed rectifier potassium channel activity;	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;GO:0008076:voltage-gated potassium channel complex;	GO:0005251:delayed rectifier potassium channel activity;GO:0005249:voltage-gated potassium channel activity;	K04900	-
ENSMUSG00000087547	641	22	1.78	33	2.93	108	7.75	71	6.60	58.0614543230823	3.33849854363796	1.73919941088036	0.421092142341737	4.13021102984371	3.62430394051167e-05	0.000560797947767971	Ups	2	157437497	157439246	-	Platr27	pluripotency associated transcript 27 [Source:MGI Symbol%3BAcc:MGI:1925566]	-	-	-	-	-
ENSMUSG00000011382	7408	185	1.30	206	1.58	86	0.53	84	0.68	138.255691472468	0.453663606669462	-1.14030516493953	0.276150754786268	-4.12928498356665	3.63893130882833e-05	0.000562493676306185	Down	7	45120411	45138229	-	Dhdh	dihydrodiol dehydrogenase (dimeric) [Source:MGI Symbol%3BAcc:MGI:1919005]	GO:0042843:D-xylose catabolic process;	-	GO:0047837:D-xylose 1-dehydrogenase (NADP+) activity;GO:0000166:nucleotide binding;GO:0047115:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;	K00078	;ko00040 Pentose and glucuronate interconversions;ko00980 Metabolism of xenobiotics by cytochrome P450;ko01100 Metabolic pathways;
ENSMUSG00000037104	6416	273	2.21	372	3.30	156	1.12	144	1.34	233.274463770178	0.483348964702595	-1.04886294337558	0.254078314819497	-4.12810886328776	3.6575895328762e-05	0.000564808438037499	Down	17	87415107	87445267	+	Socs5	suppressor of cytokine signaling 5 [Source:MGI Symbol%3BAcc:MGI:2385459]	GO:0071404:cellular response to low-density lipoprotein particle stimulus;GO:0019221:cytokine-mediated signaling pathway;GO:0007173:epidermal growth factor receptor signaling pathway;GO:0035556:intracellular signal transduction;GO:0007175:negative regulation of epidermal growth factor-activated receptor activity;GO:0050728:negative regulation of inflammatory response;GO:0032715:negative regulation of interleukin-6 production;GO:0071638:negative regulation of monocyte chemotactic protein-1 production;GO:0009968:negative regulation of signal transduction;GO:0045629:negative regulation of T-helper 2 cell differentiation;GO:0046854:phosphatidylinositol phosphorylation;GO:0032436:positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0045627:positive regulation of T-helper 1 cell differentiation;GO:0016567:protein ubiquitination;GO:0007259:JAK-STAT cascade;GO:0040008:regulation of growth;	GO:0005737:cytoplasm;GO:0005942:phosphatidylinositol 3-kinase complex;	GO:0046935:1-phosphatidylinositol-3-kinase regulator activity;GO:0005154:epidermal growth factor receptor binding;GO:0019210:kinase inhibitor activity;GO:0030971:receptor tyrosine kinase binding;	K04698	;ko04630 JAK-STAT signaling pathway;ko04917 Prolactin signaling pathway;
ENSMUSG00000003283	2092	126	3.13	117	3.18	55	1.21	31	0.88	80.2106800225452	0.363659320846903	-1.4593405408143	0.35378571327185	-4.12492784775891	3.70850997698572e-05	0.00057165318288048	Down	2	152950388	152993361	+	Hck	hemopoietic cell kinase [Source:MGI Symbol%3BAcc:MGI:96052]	GO:0030154:cell differentiation;GO:0050830:defense response to Gram-positive bacterium;GO:0006887:exocytosis;GO:0006954:inflammatory response;GO:0045087:innate immune response;GO:0043066:negative regulation of apoptotic process;GO:0018108:peptidyl-tyrosine phosphorylation;GO:0006909:phagocytosis;GO:2000251:positive regulation of actin cytoskeleton reorganization;GO:0008284:positive regulation of cell proliferation;GO:0046777:protein autophosphorylation;GO:0008360:regulation of cell shape;GO:0051090:regulation of sequence-specific DNA binding transcription factor activity;GO:0050764:regulation of phagocytosis;GO:0071801:regulation of podosome assembly;GO:0007169:transmembrane receptor protein tyrosine kinase signaling pathway;	GO:0005901:caveola;GO:0042995:cell projection;GO:0005856:cytoskeleton;GO:0005829:cytosol;GO:0031234:extrinsic component of cytoplasmic side of plasma membrane;GO:0005925:focal adhesion;GO:0005794:Golgi apparatus;GO:0043231:intracellular membrane-bounded organelle;GO:0005764:lysosome;GO:0005634:nucleus;GO:0005886:plasma membrane;GO:0030133:transport vesicle;	GO:0005524:ATP binding;GO:0004715:non-membrane spanning protein tyrosine kinase activity;GO:0001784:phosphotyrosine binding;GO:0004713:protein tyrosine kinase activity;GO:0005102:receptor binding;GO:0004714:transmembrane receptor protein tyrosine kinase activity;	K08893	;ko04062 Chemokine signaling pathway;ko04666 Fc gamma R-mediated phagocytosis;ko05167 Kaposi sarcoma-associated herpesvirus infection;
ENSMUSG00000024960	6960	200	1.49	204	1.67	85	0.56	91	0.78	143.018362451205	0.456503631930264	-1.13130175659038	0.274278694061681	-4.1246432226922	3.71309880102359e-05	0.00057165318288048	Down	19	6929693	6953838	-	Plcb3	phospholipase C%2C beta 3 [Source:MGI Symbol%3BAcc:MGI:104778]	GO:0007186:G-protein coupled receptor signaling pathway;GO:0032957:inositol trisphosphate metabolic process;GO:0031161:phosphatidylinositol catabolic process;GO:0046488:phosphatidylinositol metabolic process;GO:0048015:phosphatidylinositol-mediated signaling;GO:0006892:post-Golgi vesicle-mediated transport;GO:0003073:regulation of systemic arterial blood pressure;	GO:0005829:cytosol;GO:0005634:nucleus;GO:0032991:macromolecular complex;GO:0042383:sarcolemma;	GO:0005509:calcium ion binding;GO:0005516:calmodulin binding;GO:0004435:phosphatidylinositol phospholipase C activity;	K05858	;ko00562 Inositol phosphate metabolism;ko01100 Metabolic pathways;ko04015 Rap1 signaling pathway;ko04020 Calcium signaling pathway;ko04022 cGMP-PKG signaling pathway;ko04062 Chemokine signaling pathway;ko04070 Phosphatidylinositol signaling system;ko04071 Sphingolipid signaling pathway;ko04072 Phospholipase D signaling pathway;ko04261 Adrenergic signaling in cardiomyocytes;ko04270 Vascular smooth muscle contraction;ko04310 Wnt signaling pathway;ko04361 Axon regeneration;ko04371 Apelin signaling pathway;ko04540 Gap junction;ko04611 Platelet activation;ko04613 Neutrophil extracellular trap formation;ko04621 NOD-like receptor signaling pathway;ko04713 Circadian entrainment;ko04720 Long-term potentiation;ko04723 Retrograde endocannabinoid signaling;ko04724 Glutamatergic synapse;ko04725 Cholinergic synapse;ko04726 Serotonergic synapse;ko04728 Dopaminergic synapse;ko04730 Long-term depression;ko04742 Taste transduction;ko04745 Phototransduction - fly;ko04750 Inflammatory mediator regulation of TRP channels;ko04911 Insulin secretion;ko04912 GnRH signaling pathway;ko04915 Estrogen signaling pathway;ko04916 Melanogenesis;ko04918 Thyroid hormone synthesis;ko04919 Thyroid hormone signaling pathway;ko04921 Oxytocin signaling pathway;ko04922 Glucagon signaling pathway;ko04924 Renin secretion;ko04925 Aldosterone synthesis and secretion;ko04926 Relaxin signaling pathway;ko04927 Cortisol synthesis and secretion;ko04928 Parathyroid hormone synthesis, secretion and action;ko04929 GnRH secretion;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko04934 Cushing syndrome;ko04935 Growth hormone synthesis, secretion and action;ko04961 Endocrine and other factor-regulated calcium reabsorption;ko04970 Salivary secretion;ko04971 Gastric acid secretion;ko04972 Pancreatic secretion;ko04973 Carbohydrate digestion and absorption;ko05010 Alzheimer disease;ko05016 Huntington disease;ko05017 Spinocerebellar ataxia;ko05022 Pathways of neurodegeneration - multiple diseases;ko05131 Shigellosis;ko05142 Chagas disease;ko05143 African trypanosomiasis;ko05146 Amoebiasis;ko05163 Human cytomegalovirus infection;ko05200 Pathways in cancer;
ENSMUSG00000032842	6856	196	1.48	260	2.16	119	0.80	77	0.67	159.957317198139	0.441024808798666	-1.18106828145354	0.286498724216007	-4.12242073567863	3.74911634885851e-05	0.000576041584102168	Down	17	46614147	46639278	-	Abcc10	ATP-binding cassette%2C sub-family C (CFTR/MRP)%2C member 10 [Source:MGI Symbol%3BAcc:MGI:2386976]	GO:0006691:leukotriene metabolic process;GO:0071716:leukotriene transport;GO:0055085:transmembrane transport;	GO:0016323:basolateral plasma membrane;GO:0016021:integral component of membrane;GO:0016020:membrane;GO:0005886:plasma membrane;	GO:0015431:glutathione S-conjugate-exporting ATPase activity;GO:0008559:xenobiotic-transporting ATPase activity;GO:0005524:ATP binding;GO:0042626:ATPase activity, coupled to transmembrane movement of substances;	K05674	;ko02010 ABC transporters;
ENSMUSG00000089706	6412	1	0.01	3	0.03	30	0.22	30	0.28	16.2522649703467	15.6528792486992	3.96835615113513	0.965179480186167	4.11152146580002	3.93060322397147e-05	0.000597342614830313	Ups	1	97958839	97985405	-	B230216N24Rik	RIKEN cDNA B230216N24 gene [Source:MGI Symbol%3BAcc:MGI:1925853]	-	-	-	-	-
ENSMUSG00000030882	15081	59	0.20	64	0.24	14	0.04	14	0.06	37.0134597051899	0.237397201102836	-2.07462516908556	0.505655031538837	-4.10284688114731	4.08097344523896e-05	0.000618356193767729	Down	7	105300034	105371006	+	Dnhd1	dynein heavy chain domain 1 [Source:MGI Symbol%3BAcc:MGI:1924755]	GO:0003341:cilium movement;GO:0007018:microtubule-based movement;	GO:0030286:dynein complex;GO:0070062:extracellular exosome;GO:0036156:inner dynein arm;	GO:0005524:ATP binding;GO:0008569:ATP-dependent microtubule motor activity, minus-end-directed;GO:0045505:dynein intermediate chain binding;GO:0051959:dynein light intermediate chain binding;	-	-
ENSMUSG00000061414	7824	186	1.23	176	1.28	52	0.31	80	0.61	122.074183248713	0.387511972499842	-1.36768721056676	0.334234003996543	-4.09200498516873	4.2765945577287e-05	0.000642914715178549	Down	6	127538301	127651211	+	Cracr2a	calcium release activated channel regulator 2A [Source:MGI Symbol%3BAcc:MGI:2685919]	GO:0032237:activation of store-operated calcium channel activity;GO:0016197:endosomal transport;GO:0051928:positive regulation of calcium ion transport;GO:0046330:positive regulation of JNK cascade;GO:0034776:response to histamine;GO:0002115:store-operated calcium entry;GO:0045063:T-helper 1 cell differentiation;	GO:0005737:cytoplasm;GO:0000139:Golgi membrane;GO:0001772:immunological synapse;GO:0005815:microtubule organizing center;GO:0005886:plasma membrane;GO:0032588:trans-Golgi network membrane;GO:0031982:vesicle;GO:0033093:Weibel-Palade body;	GO:0005509:calcium ion binding;GO:0005525:GTP binding;GO:0003924:GTPase activity;	K17199	-
ENSMUSG00000026536	1785	683	19.86	456	14.54	160	4.12	61	2.04	328.693604425627	0.196086498816314	-2.35043789011354	0.574868336982848	-4.08865428638778	4.33882922038256e-05	0.000649722727200646	Down	1	173723911	173740612	-	Ifi211	interferon activated gene 211 [Source:MGI Symbol%3BAcc:MGI:3041120]	GO:0002218:activation of innate immune response;GO:0035458:cellular response to interferon-beta;GO:0032731:positive regulation of interleukin-1 beta production;GO:0009617:response to bacterium;	GO:0005829:cytosol;GO:0034399:nuclear periphery;GO:0016607:nuclear speck;GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0001227:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003690:double-stranded DNA binding;GO:0042802:identical protein binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K12971	;ko04623 Cytosolic DNA-sensing pathway;
ENSMUSG00000006800	5871	5	0.04	10	0.10	81	0.63	26	0.26	29.5466971261154	7.10676503892447	2.82919300227074	0.692475875859563	4.08561958748222	4.39593516271761e-05	0.000656990933578088	Ups	2	165915009	165997583	-	Sulf2	sulfatase 2 [Source:MGI Symbol%3BAcc:MGI:1919293]	GO:0060348:bone development;GO:0051216:cartilage development;GO:0002063:chondrocyte development;GO:0048706:embryonic skeletal system development;GO:0014846:esophagus smooth muscle contraction;GO:0035860:glial cell-derived neurotrophic factor receptor signaling pathway;GO:0032836:glomerular basement membrane development;GO:0003094:glomerular filtration;GO:0030201:heparan sulfate proteoglycan metabolic process;GO:0060384:innervation;GO:0001822:kidney development;GO:0097421:liver regeneration;GO:0040037:negative regulation of fibroblast growth factor receptor signaling pathway;GO:0090263:positive regulation of canonical Wnt signaling pathway;GO:0010575:positive regulation of vascular endothelial growth factor production;GO:0030177:positive regulation of Wnt signaling pathway;GO:2000345:regulation of hepatocyte proliferation;GO:0009611:response to wounding;GO:0006790:sulfur compound metabolic process;	GO:0009986:cell surface;GO:0005783:endoplasmic reticulum;GO:0005615:extracellular space;GO:0005795:Golgi stack;GO:0005886:plasma membrane;	GO:0004065:arylsulfatase activity;GO:0005509:calcium ion binding;GO:0005539:glycosaminoglycan binding;GO:0008449:N-acetylglucosamine-6-sulfatase activity;	K14607	-
ENSMUSG00000047090	3363	186	2.87	234	3.96	105	1.44	81	1.43	149.008807786357	0.457656075594808	-1.12766426168257	0.277042445781453	-4.07036639639017	4.69392546337789e-05	0.000697448188521672	Down	10	128635905	128640239	-	Tmem198b	transmembrane protein 198b [Source:MGI Symbol%3BAcc:MGI:1921077]	-	-	-	-	-
ENSMUSG00000000125	3076	2	0.03	3	0.06	29	0.43	31	0.60	16.5374213404615	12.5811473189512	3.65319158752473	0.900844963325516	4.05529445825926	5.00711856883644e-05	0.000734026349278565	Ups	11	103664976	103708783	+	Wnt3	wingless-type MMTV integration site family%2C member 3 [Source:MGI Symbol%3BAcc:MGI:98955]	GO:0048646:anatomical structure formation involved in morphogenesis;GO:0009887:organ morphogenesis;GO:0009948:anterior/posterior axis specification;GO:0009952:anterior/posterior pattern specification;GO:0007411:axon guidance;GO:0060070:canonical Wnt signaling pathway;GO:0044338:canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation;GO:0044339:canonical Wnt signaling pathway involved in osteoblast differentiation;GO:0045165:cell fate commitment;GO:0000902:cell morphogenesis;GO:0007267:cell-cell signaling;GO:0009950:dorsal/ventral axis specification;GO:0035115:embryonic forelimb morphogenesis;GO:0035116:embryonic hindlimb morphogenesis;GO:0007276:gamete generation;GO:0060323:head morphogenesis;GO:0060174:limb bud formation;GO:0060173:limb development;GO:0061180:mammary gland epithelium development;GO:0001707:mesoderm formation;GO:0048843:negative regulation of axon extension involved in axon guidance;GO:0030182:neuron differentiation;GO:0048697:positive regulation of collateral sprouting in absence of injury;GO:0010628:positive regulation of gene expression;GO:0030177:positive regulation of Wnt signaling pathway;GO:0050767:regulation of neurogenesis;GO:0007165:signal transduction;GO:0060064:Spemann organizer formation at the anterior end of the primitive streak;GO:0072089:stem cell proliferation;	GO:0005737:cytoplasm;GO:0005788:endoplasmic reticulum lumen;GO:0031012:extracellular matrix;GO:0005615:extracellular space;	GO:0005125:cytokine activity;GO:0005109:frizzled binding;GO:0019904:protein domain specific binding;GO:0048018:receptor agonist activity;GO:0005102:receptor binding;	K00312	;ko04150 mTOR signaling pathway;ko04310 Wnt signaling pathway;ko04390 Hippo signaling pathway;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04916 Melanogenesis;ko04934 Cushing syndrome;ko05010 Alzheimer disease;ko05022 Pathways of neurodegeneration - multiple diseases;ko05165 Human papillomavirus infection;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05206 MicroRNAs in cancer;ko05217 Basal cell carcinoma;ko05224 Breast cancer;ko05225 Hepatocellular carcinoma;ko05226 Gastric cancer;
ENSMUSG00000020432	2178	203	4.84	190	4.96	93	1.96	86	2.35	140.67479317705	0.475317315756622	-1.07303713507087	0.2648274940425	-4.05183434201384	5.08176418691232e-05	0.000742131162305843	Down	11	3867192	3882159	-	Tcn2	transcobalamin 2 [Source:MGI Symbol%3BAcc:MGI:98534]	GO:0015889:cobalamin transport;GO:0006824:cobalt ion transport;	GO:0005615:extracellular space;	GO:0031419:cobalamin binding;GO:0046872:metal ion binding;	K14619	;ko04977 Vitamin digestion and absorption;
ENSMUSG00000037465	4179	182	2.26	121	1.65	291	3.20	303	4.32	224.570707911054	2.06646920250964	1.04716786276026	0.25849251465	4.05105681368812	5.09868244944429e-05	0.000743893403232909	Ups	15	38291707	38300950	-	Klf10	Kruppel-like factor 10 [Source:MGI Symbol%3BAcc:MGI:1101353]	GO:0030282:bone mineralization;GO:1901653:cellular response to peptide;GO:0009267:cellular response to starvation;GO:0007623:circadian rhythm;GO:0045892:negative regulation of transcription, DNA-templated;GO:0045672:positive regulation of osteoclast differentiation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0042752:regulation of circadian rhythm;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0006355:regulation of transcription, DNA-templated;GO:0035019:somatic stem cell maintenance;	GO:0005634:nucleus;	GO:0001046:core promoter sequence-specific DNA binding;GO:0003677:DNA binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046872:metal ion binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K09209	-
ENSMUSG00000041298	10496	242	1.20	308	1.67	143	0.63	119	0.68	200.024608843194	0.49351043622294	-1.0188475013346	0.251843878171451	-4.04555198534936	5.21999798386463e-05	0.000758705678526827	Down	5	148808394	148866130	-	Katnal1	katanin p60 subunit A-like 1 [Source:MGI Symbol%3BAcc:MGI:2387638]	GO:0031122:cytoplasmic microtubule organization;GO:0051013:microtubule severing;GO:0007283:spermatogenesis;	GO:0005813:centrosome;GO:0005737:cytoplasm;GO:0005874:microtubule;GO:0015630:microtubule cytoskeleton;GO:0005634:nucleus;GO:0005819:spindle;GO:0000922:spindle pole;	GO:0005524:ATP binding;GO:0042802:identical protein binding;GO:0016853:isomerase activity;GO:0008017:microtubule binding;GO:0008568:microtubule-severing ATPase activity;	K07767	-
ENSMUSG00000053964	2315	96	2.15	138	3.39	44	0.87	35	0.90	76.9645917018059	0.348756414434583	-1.51970834321332	0.375716542263747	-4.04482681027792	5.23618183079018e-05	0.000760337236679324	Down	7	28533279	28541133	+	Lgals4	lectin%2C galactose binding%2C soluble 4 [Source:MGI Symbol%3BAcc:MGI:107536]	-	GO:0005615:extracellular space;	GO:0030246:carbohydrate binding;GO:0016936:galactoside binding;	K10091	-
ENSMUSG00000121029	1598	23	0.75	30	1.07	81	2.33	84	3.13	54.9720992439834	3.25701884671198	1.70355206790061	0.421342738840953	4.04315041143657	5.27377648683199e-05	0.000765071794220263	Ups	11	99046002	99053007	+	-	novel transcript	-	-	-	-	-
ENSMUSG00000034591	5349	78	0.76	126	1.34	20	0.17	33	0.37	63.6505228095884	0.274358115377397	-1.86586784424245	0.462184232671302	-4.03706511894234	5.41240491430548e-05	0.000780017076653761	Down	10	83066712	83173746	-	Slc41a2	solute carrier family 41%2C member 2 [Source:MGI Symbol%3BAcc:MGI:2442940]	GO:0030001:metal ion transport;	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0022890:inorganic cation transmembrane transporter activity;	K15122	-
ENSMUSG00000062232	14051	278	1.03	206	0.83	105	0.34	112	0.47	172.371964390609	0.471835589389611	-1.08364385329292	0.269140115161031	-4.02631860599658	5.66569089358001e-05	0.000809062216606068	Down	3	78969823	79193824	-	Rapgef2	Rap guanine nucleotide exchange factor (GEF) 2 [Source:MGI Symbol%3BAcc:MGI:2659071]	GO:0071880:adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0001568:blood vessel development;GO:0031547:brain-derived neurotrophic factor receptor signaling pathway;GO:0019933:cAMP-mediated signaling;GO:0071320:cellular response to cAMP;GO:0071321:cellular response to cGMP;GO:1990090:cellular response to nerve growth factor stimulus;GO:0061028:establishment of endothelial barrier;GO:0090557:establishment of endothelial intestinal barrier;GO:0021884:forebrain neuron development;GO:0007186:G-protein coupled receptor signaling pathway;GO:0030033:microvillus assembly;GO:0008285:negative regulation of cell proliferation;GO:0050774:negative regulation of dendrite morphogenesis;GO:0048022:negative regulation of melanin biosynthetic process;GO:0038180:nerve growth factor signaling pathway;GO:0001764:neuron migration;GO:0031175:neuron projection development;GO:0007218:neuropeptide signaling pathway;GO:2000481:positive regulation of cAMP-dependent protein kinase activity;GO:0043950:positive regulation of cAMP-mediated signaling;GO:2000670:positive regulation of dendritic cell apoptotic process;GO:0070374:positive regulation of ERK1 and ERK2 cascade;GO:0043547:positive regulation of GTPase activity;GO:2001224:positive regulation of neuron migration;GO:0010976:positive regulation of neuron projection development;GO:0032092:positive regulation of protein binding;GO:0045860:positive regulation of protein kinase activity;GO:2001214:positive regulation of vasculogenesis;GO:0072659:protein localization to plasma membrane;GO:0032486:Rap protein signal transduction;GO:1901888:regulation of cell junction assembly;GO:0048167:regulation of synaptic plasticity;GO:0021591:ventricular system development;	GO:0016324:apical plasma membrane;GO:0005923:bicellular tight junction;GO:0005911:cell-cell junction;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0030139:endocytic vesicle;GO:0005770:late endosome;GO:0016020:membrane;GO:0043005:neuron projection;GO:0043025:neuronal cell body;GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;GO:0032991:macromolecular complex;GO:0045202:synapse;	GO:0031697:beta-1 adrenergic receptor binding;GO:0030552:cAMP binding;GO:0005096:GTPase activator activity;GO:0005085:guanyl-nucleotide exchange factor activity;GO:0030165:PDZ domain binding;GO:0070300:phosphatidic acid binding;GO:0019901:protein kinase binding;GO:0050699:WW domain binding;	K08018	;ko04010 MAPK signaling pathway;ko04015 Rap1 signaling pathway;ko04530 Tight junction;
ENSMUSG00000118344	509	35	3.57	36	4.02	5	0.45	3	0.35	19.2261892435338	0.116358077886344	-3.10335672495169	0.770770774540321	-4.02630305592801	5.66606540028514e-05	0.000809062216606068	Down	19	4324015	4325671	+	Gm50152	predicted gene%2C 50152 [Source:MGI Symbol%3BAcc:MGI:6302910]	-	-	-	-	-
ENSMUSG00000016356	5142	50	0.50	29	0.32	7	0.06	2	0.02	21.1975234449468	0.116908233546121	-3.09655155613959	0.770716292440795	-4.01775800837564	5.87544887254047e-05	0.000834978063128226	Down	2	180628328	180660156	+	Col20a1	collagen%2C type XX%2C alpha 1 [Source:MGI Symbol%3BAcc:MGI:1920618]	-	GO:0005581:collagen trimer;GO:0005615:extracellular space;	-	-	-
ENSMUSG00000110070	528	0	0.00	5	0.54	42	3.66	25	2.82	17.8777507122012	13.6043709625662	3.76599834583977	0.938046533577437	4.01472444173675	5.95152862470852e-05	0.000843444916185587	Ups	7	45017601	45018128	+	Gm45619	predicted gene 45619 [Source:MGI Symbol%3BAcc:MGI:5791455]	-	-	-	-	-
ENSMUSG00000052062	13153	215	0.85	176	0.76	98	0.34	80	0.36	139.485395380158	0.473833862687028	-1.07754678996701	0.268432055127719	-4.01422545997467	5.96413173926924e-05	0.000844450564080836	Down	1	61677983	62681443	+	Pard3b	par-3 family cell polarity regulator beta [Source:MGI Symbol%3BAcc:MGI:1919301]	GO:0007155:cell adhesion;GO:0007049:cell cycle;GO:0051301:cell division;GO:0030010:establishment of cell polarity;GO:0051660:establishment of centrosome localization;GO:0045197:establishment or maintenance of epithelial cell apical/basal polarity;GO:0000226:microtubule cytoskeleton organization;GO:0008104:protein localization;	GO:0005912:adherens junction;GO:0043296:apical junction complex;GO:0016324:apical plasma membrane;GO:0005923:bicellular tight junction;GO:0005938:cell cortex;GO:0030054:cell junction;GO:0012505:endomembrane system;GO:0032991:macromolecular complex;	GO:0035091:phosphatidylinositol binding;	-	-
ENSMUSG00000107320	7004	139	1.03	176	1.43	24	0.16	61	0.52	99.251045772178	0.290721997333591	-1.78228785848913	0.444400547789278	-4.01054379288082	6.05790625286787e-05	0.000852219582398862	Down	6	28219166	28226169	-	Gm42549	predicted gene 42549 [Source:MGI Symbol%3BAcc:MGI:5662686]	-	-	-	-	-
ENSMUSG00000009739	6949	174	1.30	249	2.04	110	0.73	61	0.52	145.489023479017	0.412006503811798	-1.27926098334545	0.319351923874993	-4.00580327753469	6.18070742089646e-05	0.000866315974332965	Down	15	100473199	100497865	-	Pou6f1	POU domain%2C class 6%2C transcription factor 1 [Source:MGI Symbol%3BAcc:MGI:102935]	GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005634:nucleus;	GO:0003677:DNA binding;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001227:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043565:sequence-specific DNA binding;	K09368	-
ENSMUSG00000086359	1072	11	0.53	11	0.58	55	2.36	44	2.44	30.2603043151481	4.66997846837559	2.22341589819203	0.555365780115992	4.00351620102999	6.24079252400495e-05	0.000869256705771802	Ups	11	63855052	63858866	+	9630013K17Rik	RIKEN cDNA 9630013K17 gene [Source:MGI Symbol%3BAcc:MGI:1926133]	-	-	-	-	-
ENSMUSG00000007989	12804	2	0.01	2	0.01	22	0.08	36	0.17	16.0747145894315	15.4942522613341	3.95366122832748	0.987662851114552	4.00304742034782	6.25317622749373e-05	0.000869256705771802	Ups	14	65429898	65499912	-	Fzd3	frizzled class receptor 3 [Source:MGI Symbol%3BAcc:MGI:108476]	GO:0060070:canonical Wnt signaling pathway;GO:0033278:cell proliferation in midbrain;GO:0071679:commissural neuron axon guidance;GO:0001736:establishment of planar polarity;GO:0001942:hair follicle development;GO:0042472:inner ear morphogenesis;GO:0030901:midbrain development;GO:1900118:negative regulation of execution phase of apoptosis;GO:0045976:negative regulation of mitotic cell cycle, embryonic;GO:0001843:neural tube closure;GO:0001764:neuron migration;GO:0002052:positive regulation of neuroblast proliferation;GO:0036342:post-anal tail morphogenesis;GO:0042493:response to drug;GO:0051602:response to electrical stimulus;GO:0061549:sympathetic ganglion development;	GO:0045177:apical part of cell;GO:0016324:apical plasma membrane;GO:0030424:axon;GO:0009986:cell surface;GO:0005737:cytoplasm;GO:0030425:dendrite;GO:0032433:filopodium tip;GO:0016021:integral component of membrane;GO:0016328:lateral plasma membrane;GO:0043025:neuronal cell body;GO:0005886:plasma membrane;	GO:0004930:G-protein coupled receptor activity;GO:0030165:PDZ domain binding;GO:0042813:Wnt-activated receptor activity;GO:0017147:Wnt-protein binding;	K02329	;ko04150 mTOR signaling pathway;ko04310 Wnt signaling pathway;ko04360 Axon guidance;ko04390 Hippo signaling pathway;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04916 Melanogenesis;ko04934 Cushing syndrome;ko05010 Alzheimer disease;ko05022 Pathways of neurodegeneration - multiple diseases;ko05165 Human papillomavirus infection;ko05200 Pathways in cancer;ko05205 Proteoglycans in cancer;ko05206 MicroRNAs in cancer;ko05217 Basal cell carcinoma;ko05224 Breast cancer;ko05225 Hepatocellular carcinoma;ko05226 Gastric cancer;
ENSMUSG00000117666	1058	44	2.16	37	1.99	100	4.35	113	6.36	74.1327831789221	2.77151263403244	1.47067358421316	0.368102514244043	3.99528263813526	6.46171181723621e-05	0.000894258926042419	Ups	19	6144449	6148271	+	Gm550	predicted gene 550 [Source:MGI Symbol%3BAcc:MGI:2685396]	-	-	-	K17390	;ko05206 MicroRNAs in cancer;
ENSMUSG00000081344	171	63	19.13	77	25.62	201	54.09	124	43.19	114.878382687126	2.37839628829223	1.24998911690067	0.313018533277512	3.99333900076923	6.51493202415757e-05	0.000899189627888679	Ups	2	172351441	172351611	-	Gm14303	predicted gene 14303 [Source:MGI Symbol%3BAcc:MGI:3651379]	GO:0002181:cytoplasmic translation;GO:0006412:translation;	GO:0098556:cytoplasmic side of rough endoplasmic reticulum membrane;GO:0005829:cytosol;GO:0022627:cytosolic small ribosomal subunit;GO:0070062:extracellular exosome;GO:0005925:focal adhesion;GO:0005654:nucleoplasm;GO:0042788:polysomal ribosome;GO:0015935:small ribosomal subunit;	GO:0003735:structural constituent of ribosome;GO:0008270:zinc ion binding;	K02980	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000041831	5062	11	0.11	16	0.18	64	0.58	48	0.56	34.6929403133048	4.28148948197019	2.09811278130516	0.525563325553598	3.99212174688013	6.54847355933326e-05	0.000903006237039714	Ups	17	6926492	7005443	+	Sytl3	synaptotagmin-like 3 [Source:MGI Symbol%3BAcc:MGI:1933367]	GO:0006887:exocytosis;GO:0006886:intracellular protein transport;	GO:0070382:exocytic vesicle;GO:0019897:extrinsic component of plasma membrane;GO:0016020:membrane;GO:0005886:plasma membrane;	GO:0005544:calcium-dependent phospholipid binding;GO:0042043:neurexin family protein binding;GO:0005543:phospholipid binding;GO:0031267:small GTPase binding;GO:0008270:zinc ion binding;	K17598	-
ENSMUSG00000078606	9275	117	0.65	52	0.32	25	0.12	15	0.10	50.5053081455617	0.245826027443336	-2.02429042215675	0.507726999105721	-3.9869662746362	6.69235341948332e-05	0.000916254886913904	Down	7	105544346	105603174	-	Gvin2	GTPase%2C very large interferon inducible%2C family member 2 [Source:MGI Symbol%3BAcc:MGI:3782245]	-	GO:0005829:cytosol;GO:0005634:nucleus;	GO:0005525:GTP binding;	-	-
ENSMUSG00000049362	2867	11	0.20	19	0.38	82	1.32	45	0.93	38.7409532744454	4.30774728781138	2.10693361726484	0.528897443401724	3.98363358255926	6.78694927346078e-05	0.000928377164667686	Ups	16	58615570	58620631	-	Olfr173	olfactory receptor 173 [Source:MGI Symbol%3BAcc:MGI:3030007]	-	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0004930:G-protein coupled receptor activity;GO:0005549:odorant binding;GO:0004984:olfactory receptor activity;	K04257	;ko04740 Olfactory transduction;
ENSMUSG00000113136	1348	13	0.50	8	0.34	85	2.90	30	1.33	32.9700925873207	5.52454530415022	2.46585572885841	0.622231837891306	3.96292117937102	7.40382312398033e-05	0.000988939231560229	Ups	12	99609334	99613482	+	Gm19951	predicted gene%2C 19951 [Source:MGI Symbol%3BAcc:MGI:5012136]	-	-	-	-	-
ENSMUSG00000103165	1000	12	0.62	10	0.57	48	2.21	50	2.98	30.3125657636436	4.67799040846192	2.22588890365729	0.56181821983513	3.96193790993552	7.43438760717952e-05	0.000991294778856441	Ups	9	88614051	88615050	+	Gm37560	predicted gene%2C 37560 [Source:MGI Symbol%3BAcc:MGI:5610788]	-	-	-	-	-
ENSMUSG00000044807	5596	194	1.80	172	1.75	76	0.62	83	0.88	129.315549894561	0.45627493044774	-1.13202470630718	0.285823171764904	-3.96057709148331	7.4768849296942e-05	0.000994367333147709	Down	11	50701913	50718551	-	Zfp354c	zinc finger protein 354C [Source:MGI Symbol%3BAcc:MGI:1353621]	GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005634:nucleus;GO:0005654:nucleoplasm;	GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046872:metal ion binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000002059	2385	23	0.50	13	0.31	86	1.66	50	1.25	42.3885800435884	3.88840300449859	1.95917775146966	0.495601465742814	3.95313147133901	7.71350269263377e-05	0.00102140630646672	Ups	11	78079256	78083019	+	Rab34	RAB34%2C member RAS oncogene family [Source:MGI Symbol%3BAcc:MGI:104606]	GO:0019882:antigen processing and presentation;GO:0030030:cell projection organization;GO:0071333:cellular response to glucose stimulus;GO:0006897:endocytosis;GO:0043001:Golgi to plasma membrane protein transport;GO:0007041:lysosomal transport;GO:0032418:lysosome localization;GO:0090382:phagosome maturation;GO:0090385:phagosome-lysosome fusion;GO:1900426:positive regulation of defense response to bacterium;GO:0050714:positive regulation of protein secretion;GO:0045880:positive regulation of smoothened signaling pathway;GO:0072659:protein localization to plasma membrane;	GO:0005929:cilium;GO:0031410:cytoplasmic vesicle;GO:0005769:early endosome;GO:0005794:Golgi apparatus;GO:0031985:Golgi cisterna;GO:0005795:Golgi stack;GO:0005770:late endosome;GO:0048471:perinuclear region of cytoplasm;GO:0045335:phagocytic vesicle;GO:0030670:phagocytic vesicle membrane;GO:0001726:ruffle;GO:0031982:vesicle;GO:0005730:nucleolus;	GO:0005525:GTP binding;GO:0030742:GTP-dependent protein binding;GO:0003924:GTPase activity;GO:0019001:guanyl nucleotide binding;GO:0031267:small GTPase binding;	K07921	-
ENSMUSG00000001520	3757	77	1.06	70	1.06	15	0.18	23	0.36	45.4981671404876	0.27357194411693	-1.87000781115037	0.473754655862921	-3.94720724748181	7.90681096252927e-05	0.00104163605459373	Down	6	128376259	128393390	+	Nrip2	nuclear receptor interacting protein 2 [Source:MGI Symbol%3BAcc:MGI:1891884]	GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0007219:Notch signaling pathway;	GO:0005737:cytoplasm;GO:0005634:nucleus;	GO:0004190:aspartic-type endopeptidase activity;	K13215	-
ENSMUSG00000117822	1387	112	4.19	103	4.23	250	8.29	172	7.39	157.582504789079	2.02594160696765	1.01859259242521	0.258054432014361	3.9472005362362	7.90703252606691e-05	0.00104163605459373	Ups	19	17903987	17905373	+	Eef1a1-ps1	eukaryotic translation elongation factor 1 alpha 1%2C pseudogene 1 [Source:MGI Symbol%3BAcc:MGI:2388571]	GO:0071364:cellular response to epidermal growth factor stimulus;GO:1903427:negative regulation of reactive oxygen species biosynthetic process;GO:0010942:positive regulation of cell death;GO:0010976:positive regulation of neuron projection development;GO:1900022:regulation of D-erythro-sphingosine kinase activity;GO:0006412:translation;GO:0006414:translational elongation;	GO:0030864:cortical actin cytoskeleton;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0043209:myelin sheath;GO:0005730:nucleolus;GO:0005634:nucleus;GO:0005886:plasma membrane;GO:0032587:ruffle membrane;	GO:0005516:calmodulin binding;GO:0005525:GTP binding;GO:0003924:GTPase activity;GO:0042802:identical protein binding;GO:0019900:kinase binding;GO:0003729:mRNA binding;GO:0019901:protein kinase binding;GO:0003746:translation elongation factor activity;GO:0000049:tRNA binding;	K03231	;ko03013 RNA transport;ko05134 Legionellosis;ko05140 Leishmaniasis;
ENSMUSG00000113585	4932	217	2.28	302	3.48	131	1.22	108	1.30	186.802747302819	0.476370504333468	-1.06984400697753	0.271151828272819	-3.94555335950419	7.96158990669708e-05	0.00104702418206941	Down	12	110440945	110452649	-	Gm19605	predicted gene%2C 19605 [Source:MGI Symbol%3BAcc:MGI:5011790]	-	-	-	-	-
ENSMUSG00000051590	5345	64	0.62	103	1.10	18	0.15	25	0.28	51.9157291692636	0.270213158427421	-1.88783016435492	0.47925658669607	-3.93908026881668	8.17945635625052e-05	0.00107291517336822	Down	1	127742528	127782768	-	Map3k19	mitogen-activated protein kinase kinase kinase 19 [Source:MGI Symbol%3BAcc:MGI:1203481]	-	-	GO:0005524:ATP binding;	K17533	-
ENSMUSG00000097375	5598	107	0.99	70	0.71	197	1.62	175	1.86	136.824469407855	2.19962325995372	1.1372564475956	0.288905297106079	3.93643335372293	8.27015739783628e-05	0.00108269099602927	Ups	13	48686381	48699976	-	6720427I07Rik	RIKEN cDNA 6720427I07 gene [Source:MGI Symbol%3BAcc:MGI:1924398]	-	-	-	-	-
ENSMUSG00000029650	2458	203	4.29	172	3.98	101	1.89	70	1.70	133.555124399037	0.471819479570485	-1.08369311187676	0.275844341917262	-3.92863998711927	8.54276170578396e-05	0.00111295418858531	Down	5	147815247	147831625	-	Slc46a3	solute carrier family 46%2C member 3 [Source:MGI Symbol%3BAcc:MGI:1918956]	GO:0034486:vacuolar transmembrane transport;	-	GO:0022857:transmembrane transporter activity;	K14613	;ko01523 Antifolate resistance;ko04977 Vitamin digestion and absorption;ko04978 Mineral absorption;
ENSMUSG00000015452	2141	55	1.33	84	2.23	14	0.30	19	0.53	42.4571302597679	0.248885796164936	-2.00644419637688	0.511204398476203	-3.9249353142455	8.67530464907201e-05	0.00112830467759856	Down	17	34816836	34819910	+	Ager	advanced glycosylation end product-specific receptor [Source:MGI Symbol%3BAcc:MGI:893592]	GO:0048143:astrocyte activation;GO:0014002:astrocyte development;GO:0055074:calcium ion homeostasis;	GO:0016324:apical plasma membrane;GO:0030424:axon;GO:0009925:basal plasma membrane;GO:0030054:cell junction;	GO:0001540:beta-amyloid binding;GO:0070379:high mobility group box 1 binding;GO:0042802:identical protein binding;GO:0044877:macromolecular complex binding;	K19722	;ko04613 Neutrophil extracellular trap formation;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05010 Alzheimer disease;ko05022 Pathways of neurodegeneration - multiple diseases;
ENSMUSG00000024659	2911	104	1.85	116	2.27	39	0.62	40	0.82	73.6072441758712	0.375061507826651	-1.41480088658573	0.360683750279796	-3.92255233424909	8.76158539984835e-05	0.00113759653277963	Down	19	20350792	20368308	-	Anxa1	annexin A1 [Source:MGI Symbol%3BAcc:MGI:96819]	GO:0031532:actin cytoskeleton reorganization;GO:0002250:adaptive immune response;GO:0071385:cellular response to glucocorticoid stimulus;GO:0007187:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0071621:granulocyte chemotaxis;GO:0006954:inflammatory response;GO:0045087:innate immune response;GO:0002548:monocyte chemotaxis;GO:0045920:negative regulation of exocytosis;GO:0045629:negative regulation of T-helper 2 cell differentiation;GO:0006909:phagocytosis;GO:0032743:positive regulation of interleukin-2 production;GO:0042102:positive regulation of T cell proliferation;GO:0045627:positive regulation of T-helper 1 cell differentiation;GO:0090303:positive regulation of wound healing;GO:0008360:regulation of cell shape;GO:0046883:regulation of hormone secretion;GO:0050727:regulation of inflammatory response;GO:0032652:regulation of interleukin-1 production;GO:0002685:regulation of leukocyte migration;GO:0046632:alpha-beta T cell differentiation;GO:0050482:arachidonic acid secretion;	GO:0016324:apical plasma membrane;GO:0016323:basolateral plasma membrane;GO:0005737:cytoplasm;GO:0031901:early endosome membrane;GO:0070062:extracellular exosome;GO:0005615:extracellular space;GO:0031313:extrinsic component of endosome membrane;GO:0031232:extrinsic component of external side of plasma membrane;GO:0016328:lateral plasma membrane;GO:0031514:motile cilium;GO:0005634:nucleus;GO:0001891:phagocytic cup;GO:0005884:actin filament;GO:0009986:cell surface;	GO:0005509:calcium ion binding;GO:0005544:calcium-dependent phospholipid binding;GO:0019834:phospholipase A2 inhibitor activity;GO:0048306:calcium-dependent protein binding;	K17091	-
ENSMUSG00000027520	12659	0	0.00	0	0.00	13	0.05	22	0.10	9.1279888088558	101.816595980706	6.66982892788403	1.7055763140048	3.91060128656622	9.20666424117237e-05	0.0011853483583051	Ups	1	63312424	63353735	+	Zdbf2	zinc finger%2C DBF-type containing 2 [Source:MGI Symbol%3BAcc:MGI:1921134]	-	-	-	-	-
ENSMUSG00000043079	9533	120	0.65	62	0.37	13	0.06	28	0.17	54.5793512241801	0.243152381005429	-2.04006737603168	0.522024598608366	-3.90799089060203	9.30668143741424e-05	0.00119525843925972	Down	18	60727045	60793214	-	Synpo	synaptopodin [Source:MGI Symbol%3BAcc:MGI:1099446]	GO:0030865:cortical cytoskeleton organization;GO:0032233:positive regulation of actin filament bundle assembly;GO:0048169:regulation of long-term neuronal synaptic plasticity;GO:0051492:regulation of stress fiber assembly;GO:0008542:visual learning;	GO:0015629:actin cytoskeleton;GO:0005923:bicellular tight junction;GO:0071944:cell periphery;GO:0005829:cytosol;GO:0030425:dendrite;GO:0043197:dendritic spine;GO:0005634:nucleus;GO:0043204:perikaryon;GO:0014069:postsynaptic density;GO:0097444:spine apparatus;GO:0001725:stress fiber;GO:0030018:Z disc;	GO:0003779:actin binding;	K10283	-
ENSMUSG00000015944	7560	137	0.94	179	1.35	70	0.43	61	0.48	110.099406972883	0.430044586415163	-1.21744185073451	0.313912078949855	-3.8782892802573	0.00010519358689096	0.00132979263098597	Down	5	134128550	134173182	+	Castor2	cytosolic arginine sensor for mTORC1 subunit 2 [Source:MGI Symbol%3BAcc:MGI:1933384]	GO:1903577:cellular response to L-arginine;GO:1904262:negative regulation of TORC1 signaling;GO:1902531:regulation of intracellular signal transduction;	GO:0005829:cytosol;	GO:0042802:identical protein binding;	-	-
ENSMUSG00000001946	2867	4	0.07	3	0.06	35	0.56	26	0.54	16.9924539348114	9.03076420047844	3.1748480764759	0.819105957730594	3.87599192328194	0.000106191206438981	0.0013390920719863	Ups	9	37439374	37449615	+	Esam	endothelial cell-specific adhesion molecule [Source:MGI Symbol%3BAcc:MGI:1916774]	GO:0070830:bicellular tight junction assembly;GO:0016338:calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0098609:cell-cell adhesion;GO:0034613:cellular protein localization;GO:0007156:homophilic cell adhesion via plasma membrane adhesion molecules;GO:2000249:regulation of actin cytoskeleton reorganization;GO:0030833:regulation of actin filament polymerization;	GO:0005912:adherens junction;GO:0005923:bicellular tight junction;GO:0005911:cell-cell junction;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;GO:0032991:macromolecular complex;	GO:0098632:protein binding involved in cell-cell adhesion;	K06787	;ko04514 Cell adhesion molecules;ko04670 Leukocyte transendothelial migration;
ENSMUSG00000087132	3613	0	0.00	0	0.00	19	0.24	15	0.25	8.55308500415473	95.8536134323763	6.58276091366351	1.69896090222949	3.87458057747249	0.000106808498538896	0.00134576952883766	Ups	19	4489031	4499001	+	A930001C03Rik	RIKEN cDNA A930001C03 gene [Source:MGI Symbol%3BAcc:MGI:2441838]	-	-	-	-	-
ENSMUSG00000022657	2184	156	3.71	102	2.66	60	1.26	32	0.87	84.9709149435788	0.366998779275635	-1.44615283055434	0.373527326876223	-3.87161186478214	0.000108118018096368	0.00135558600939469	Down	16	45856020	45940614	-	Cd96	CD96 antigen [Source:MGI Symbol%3BAcc:MGI:1934368]	GO:0007160:cell-matrix adhesion;GO:0006954:inflammatory response;GO:0032689:negative regulation of interferon-gamma production;GO:0002728:negative regulation of natural killer cell cytokine production;GO:0032496:response to lipopolysaccharide;	GO:0005737:cytoplasm;GO:0016021:integral component of membrane;	-	K06517	-
ENSMUSG00000054161	3843	6	0.08	12	0.18	65	0.78	32	0.50	28.2793841907355	5.45721425590288	2.44816468652906	0.632665443084124	3.86960393252194	0.000109012302874171	0.00136234282988797	Ups	7	45370636	45378916	+	Fam83e	family with sequence similarity 83%2C member E [Source:MGI Symbol%3BAcc:MGI:1921063]	GO:0007165:signal transduction;	-	GO:0019901:protein kinase binding;	-	-
ENSMUSG00000102055	364	88	12.55	99	15.48	24	3.03	34	5.56	60.468867247892	0.327133685940254	-1.61204776916677	0.417294517422967	-3.86309357506561	0.000111960095360353	0.00139011830142158	Down	1	131191067	131194486	+	Gm28913	predicted gene 28913 [Source:MGI Symbol%3BAcc:MGI:5579619]	-	-	-	-	-
ENSMUSG00000009628	9622	42	0.23	22	0.13	84	0.40	108	0.67	64.8448650561297	3.19478895476629	1.67572063102563	0.434590830447424	3.85585823175427	0.00011532431126769	0.00142381883170592	Ups	8	34006766	34075610	+	Tex15	testis expressed gene 15 [Source:MGI Symbol%3BAcc:MGI:1934816]	GO:0030154:cell differentiation;GO:0006306:DNA methylation;GO:0006281:DNA repair;GO:0009566:fertilization;GO:0031047:gene silencing by RNA;GO:0048873:homeostasis of number of cells within a tissue;GO:0007129:synapsis;GO:0030539:male genitalia development;GO:0007140:male meiosis;GO:0010529:negative regulation of transposition;GO:0034502:protein localization to chromosome;GO:0010569:regulation of double-strand break repair via homologous recombination;GO:0032880:regulation of protein localization;GO:0007283:spermatogenesis;GO:0007130:synaptonemal complex assembly;	GO:0005737:cytoplasm;GO:0005634:nucleus;	-	-	-
ENSMUSG00000050334	15142	1	0.00	0	0.00	31	0.09	32	0.13	16.2915660849842	66.1549052154007	6.04777622746941	1.57108827876831	3.84941846311188	0.000118398587008563	0.00145358201216118	Ups	13	83863381	84100589	+	C130071C03Rik	RIKEN cDNA C130071C03 gene [Source:MGI Symbol%3BAcc:MGI:2443574]	-	-	-	-	-
ENSMUSG00000049858	2497	140	2.91	150	3.42	74	1.36	48	1.14	100.860044512796	0.433228508310056	-1.2067999132424	0.313755922839676	-3.84630161662018	0.000119914136118932	0.00147101069059817	Down	10	128505763	128509942	-	Suox	sulfite oxidase [Source:MGI Symbol%3BAcc:MGI:2446117]	GO:0007584:response to nutrient;GO:0006790:sulfur compound metabolic process;	GO:0005829:cytosol;GO:0005758:mitochondrial intermembrane space;GO:0005739:mitochondrion;	GO:0020037:heme binding;GO:0030151:molybdenum ion binding;GO:0043546:molybdopterin cofactor binding;GO:0008482:sulfite oxidase activity;	K00387	;ko00920 Sulfur metabolism;ko01100 Metabolic pathways;ko01120 Microbial metabolism in diverse environments;
ENSMUSG00000036863	5751	22	0.20	14	0.14	56	0.45	73	0.76	41.9274907145828	3.80764210901307	1.92889788205531	0.501629459137286	3.84526436181136	0.000120422538915379	0.00147606651616981	Ups	3	145693625	145727475	+	Syde2	synapse defective 1%2C Rho GTPase%2C homolog 2 (C. elegans) [Source:MGI Symbol%3BAcc:MGI:3036264]	GO:0090630:activation of GTPase activity;GO:0016477:cell migration;GO:0051056:regulation of small GTPase mediated signal transduction;GO:0007165:signal transduction;	GO:0005829:cytosol;	GO:0005096:GTPase activator activity;	-	-
ENSMUSG00000040133	3899	78	1.04	67	0.98	28	0.33	10	0.15	44.3444074792014	0.266581137953826	-1.90735338926602	0.497207899358405	-3.83612849218056	0.000124989032342427	0.00151989042183884	Down	2	118107591	118203900	-	Gpr176	G protein-coupled receptor 176 [Source:MGI Symbol%3BAcc:MGI:2685858]	GO:0007193:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0048512:circadian behavior;GO:0007186:G-protein coupled receptor signaling pathway;	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0004930:G-protein coupled receptor activity;	K08442	-
ENSMUSG00000114019	2175	54	1.29	49	1.28	12	0.25	11	0.30	30.7935560106874	0.232822439111879	-2.1026979849429	0.548346139363322	-3.83461801588377	0.000125759580025875	0.00152466841212944	Down	13	93547291	93549465	+	Gm47155	predicted gene%2C 47155 [Source:MGI Symbol%3BAcc:MGI:6095924]	-	-	-	-	-
ENSMUSG00000002781	7518	163	1.13	133	1.01	70	0.43	57	0.45	103.634701097262	0.446553314056463	-1.16309566571514	0.303433480258577	-3.8331157943546	0.000126530356027901	0.00153255646076764	Down	7	45546365	45566837	+	Tmem143	transmembrane protein 143 [Source:MGI Symbol%3BAcc:MGI:1917459]	GO:0002244:hematopoietic progenitor cell differentiation;	GO:0016021:integral component of membrane;GO:0005739:mitochondrion;	-	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000032135	3350	2	0.03	3	0.05	41	0.56	18	0.32	15.6667244140829	11.9394091448495	3.5776595374459	0.933873056474988	3.83099128156688	0.000127628028321254	0.00154341339611839	Ups	9	44045766	44054024	+	Mcam	melanoma cell adhesion molecule [Source:MGI Symbol%3BAcc:MGI:1933966]	GO:0001525:angiogenesis;GO:0007155:cell adhesion;GO:0003094:glomerular filtration;GO:0007157:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0030335:positive regulation of cell migration;GO:0061042:vascular wound healing;	GO:0009897:external side of plasma membrane;GO:0005615:extracellular space;GO:0016021:integral component of membrane;GO:0005634:nucleus;GO:0005886:plasma membrane;	-	K06534	-
ENSMUSG00000118138	4072	116	1.48	60	0.84	22	0.25	26	0.38	54.646851536274	0.288805408454742	-1.79183033507996	0.468192662814192	-3.82712177570171	0.000129650382595914	0.00155926193468686	Down	19	9842288	9846359	-	Gm50322	predicted gene%2C 50322 [Source:MGI Symbol%3BAcc:MGI:6303183]	-	-	-	-	-
ENSMUSG00000038037	2908	62	1.11	48	0.94	211	3.34	89	1.82	99.9340261109776	2.76382880922381	1.46666825836998	0.383310143489311	3.82632258311442	0.000130071817329555	0.00156188038130885	Ups	16	10600104	10603400	-	Socs1	suppressor of cytokine signaling 1 [Source:MGI Symbol%3BAcc:MGI:1354910]	GO:0071230:cellular response to amino acid stimulus;GO:0071345:cellular response to cytokine stimulus;GO:0071407:cellular response to organic cyclic compound;GO:0019221:cytokine-mediated signaling pathway;GO:0045444:fat cell differentiation;GO:0035556:intracellular signal transduction;GO:0043377:negative regulation of CD8-positive, alpha-beta T cell differentiation;GO:0046627:negative regulation of insulin receptor signaling pathway;GO:0046426:negative regulation of JAK-STAT cascade;GO:0042532:negative regulation of tyrosine phosphorylation of STAT protein;GO:0046854:phosphatidylinositol phosphorylation;GO:0043372:positive regulation of CD4-positive, alpha-beta T cell differentiation;GO:0045591:positive regulation of regulatory T cell differentiation;GO:0016567:protein ubiquitination;GO:0007259:JAK-STAT cascade;GO:0010533:regulation of activation of Janus kinase activity;GO:0001817:regulation of cytokine production;GO:0040008:regulation of growth;GO:0060334:regulation of interferon-gamma-mediated signaling pathway;GO:0001932:regulation of protein phosphorylation;GO:0046425:regulation of JAK-STAT cascade;GO:0042509:regulation of tyrosine phosphorylation of STAT protein;	GO:0036464:cytoplasmic ribonucleoprotein granule;GO:0031410:cytoplasmic vesicle;GO:0005829:cytosol;GO:0005654:nucleoplasm;GO:0005942:phosphatidylinositol 3-kinase complex;	GO:0046935:1-phosphatidylinositol-3-kinase regulator activity;GO:0005159:insulin-like growth factor receptor binding;GO:0019210:kinase inhibitor activity;GO:0019901:protein kinase binding;	K04694	;ko04120 Ubiquitin mediated proteolysis;ko04380 Osteoclast differentiation;ko04630 JAK-STAT signaling pathway;ko04910 Insulin signaling pathway;ko04917 Prolactin signaling pathway;ko04930 Type II diabetes mellitus;ko04935 Growth hormone synthesis, secretion and action;ko05145 Toxoplasmosis;ko05206 MicroRNAs in cancer;
ENSMUSG00000047220	2890	21	0.38	13	0.26	74	1.18	49	1.01	38.8800123746336	3.74028932310107	1.90314987141209	0.497671107064908	3.82411163596821	0.000131244442220008	0.00157349669820297	Ups	9	108280810	108305683	-	Iho1	interactor of HORMAD1 1 [Source:MGI Symbol%3BAcc:MGI:3612242]	GO:0006310:DNA recombination;GO:0007129:synapsis;GO:0042138:meiotic DNA double-strand break formation;GO:0048477:oogenesis;GO:0060629:regulation of homologous chromosome segregation;GO:0007283:spermatogenesis;	GO:0000794:condensed nuclear chromosome;	-	-	-
ENSMUSG00000121130	1519	12	0.41	12	0.45	54	1.64	44	1.73	30.5159273625128	4.24059829211986	2.0842678242653	0.546453574866727	3.81417181646882	0.000136640382942532	0.00162547993176166	Ups	4	115910732	115912250	+	-	novel transcript%2C antisense to Nsun4	-	-	-	-	-
ENSMUSG00000040229	2090	406	10.08	453	12.33	285	6.27	138	3.93	312.830341542909	0.49996819618788	-1.0000917693227	0.262635168800293	-3.80791260321716	0.000140144782301511	0.00166201089853934	Down	X	13498328	13507097	+	Gpr34	G protein-coupled receptor 34 [Source:MGI Symbol%3BAcc:MGI:1346334]	GO:0007186:G-protein coupled receptor signaling pathway;	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0045028:G-protein coupled purinergic nucleotide receptor activity;	K08383	-
ENSMUSG00000081998	260	10	2.00	14	3.06	52	9.20	47	10.77	30.9210754403052	4.29083689324257	2.10125906123953	0.552140043219948	3.80566323171472	0.000141424706032897	0.00167295231953608	Ups	4	146565124	146565383	+	Gm13245	predicted gene 13245 [Source:MGI Symbol%3BAcc:MGI:3649656]	GO:0002181:cytoplasmic translation;GO:0006417:regulation of translation;GO:0006414:translational elongation;	GO:0005829:cytosol;GO:0022625:cytosolic large ribosomal subunit;	GO:0030295:protein kinase activator activity;GO:0043021:ribonucleoprotein complex binding;GO:0003735:structural constituent of ribosome;	K02942	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000087543	5404	153	1.47	143	1.51	65	0.55	63	0.69	104.297504486065	0.451927931426182	-1.14583536929082	0.301690543102953	-3.7980486809618	0.000145839684968301	0.00171627454282726	Down	15	79626899	79641595	+	Gm16576	predicted gene 16576 [Source:MGI Symbol%3BAcc:MGI:4414996]	-	-	-	-	-
ENSMUSG00000026409	7254	270	1.93	301	2.36	96	0.61	147	1.21	201.895520925695	0.452287840748918	-1.14468688363401	0.301432046640437	-3.79749564252353	0.000146165345299349	0.00171787140998917	Down	1	130616919	130656990	-	Pfkfb2	6-phosphofructo-2-kinase/fructose-2%2C6-biphosphatase 2 [Source:MGI Symbol%3BAcc:MGI:107815]	GO:0006003:fructose 2,6-bisphosphate metabolic process;GO:0006000:fructose metabolic process;GO:0006007:glucose catabolic process;GO:0006096:glycolytic process;GO:0006089:lactate metabolic process;GO:0033133:positive regulation of glucokinase activity;GO:0032024:positive regulation of insulin secretion;GO:0006090:pyruvate metabolic process;GO:0009749:response to glucose;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005654:nucleoplasm;	GO:0003873:6-phosphofructo-2-kinase activity;GO:0005524:ATP binding;GO:0004331:fructose-2,6-bisphosphate 2-phosphatase activity;GO:0019900:kinase binding;GO:0019901:protein kinase binding;	K19029	;ko00051 Fructose and mannose metabolism;ko01100 Metabolic pathways;ko04152 AMPK signaling pathway;ko04919 Thyroid hormone signaling pathway;
ENSMUSG00000108298	1195	176	7.65	151	7.19	90	3.47	52	2.59	114.393924469803	0.446529627214384	-1.1631721936344	0.306735726441767	-3.7920988439383	0.000149379431390047	0.00174587210437117	Down	6	48731164	48732920	-	Gm44226	predicted gene%2C 44226 [Source:MGI Symbol%3BAcc:MGI:5690618]	-	-	-	-	-
ENSMUSG00000072919	1709	131	3.98	141	4.70	65	1.75	50	1.74	94.9810455231698	0.437815938222916	-1.19160361963616	0.314609895923577	-3.78755924424454	0.000152134416791711	0.00177401456052022	Down	12	87267814	87285506	-	Noxred1	NADP+ dependent oxidoreductase domain containing 1 [Source:MGI Symbol%3BAcc:MGI:1918525]	GO:0055129:L-proline biosynthetic process;	-	GO:0004735:pyrroline-5-carboxylate reductase activity;	-	-
ENSMUSG00000073987	1965	110	2.91	91	2.64	38	0.89	35	1.06	67.1575900235195	0.379367075736297	-1.39833361838651	0.369234990187249	-3.7871102564721	0.000152409481792787	0.00177587157584392	Down	4	20042052	20066750	+	Ggh	gamma-glutamyl hydrolase [Source:MGI Symbol%3BAcc:MGI:1329035]	GO:0070500:poly-gamma-glutamate metabolic process;GO:0042493:response to drug;GO:0045471:response to ethanol;GO:0032868:response to insulin;GO:0010043:response to zinc ion;GO:0046900:tetrahydrofolylpolyglutamate metabolic process;	GO:0005829:cytosol;GO:0005615:extracellular space;GO:0005764:lysosome;GO:0042470:melanosome;GO:0005773:vacuole;	GO:0034722:gamma-glutamyl-peptidase activity;	K01307	;ko00790 Folate biosynthesis;ko01240 Biosynthesis of cofactors;ko01523 Antifolate resistance;
ENSMUSG00000045287	3525	6	0.09	8	0.13	54	0.70	27	0.46	23.3575912110075	5.88266765138226	2.55647053170477	0.675181391076437	3.78634625523225	0.000152878610997793	0.00177863476558434	Ups	11	75084609	75158595	+	Rtn4rl1	reticulon 4 receptor-like 1 [Source:MGI Symbol%3BAcc:MGI:2661375]	GO:0007411:axon guidance;GO:0022038:corpus callosum development;GO:0050919:negative chemotaxis;GO:0048681:negative regulation of axon regeneration;GO:0010977:negative regulation of neuron projection development;	GO:0046658:anchored component of plasma membrane;GO:0042995:cell projection;GO:0009986:cell surface;GO:0009897:external side of plasma membrane;GO:0016021:integral component of membrane;GO:0045121:membrane raft;GO:0043204:perikaryon;	GO:0035374:chondroitin sulfate binding;GO:0008201:heparin binding;GO:0048495:Roundabout binding;GO:0038023:signaling receptor activity;	K16660	-
ENSMUSG00000109585	2305	0	0.00	1	0.02	26	0.52	34	0.88	15.7144481477496	63.4670522781942	5.98793593321647	1.5820928797668	3.78481946906878	0.00015382019792891	0.00178510328153723	Ups	8	58094552	58096856	-	Gm45358	predicted gene 45358 [Source:MGI Symbol%3BAcc:MGI:5791194]	-	-	-	-	-
ENSMUSG00000022768	4501	85	0.98	55	0.70	172	1.76	133	1.76	110.423999218458	2.26710351666187	1.18085026649341	0.312020109914298	3.78453256367917	0.000153997744013389	0.00178510328153723	Ups	16	16956928	16965093	-	Ccdc116	coiled-coil domain containing 116 [Source:MGI Symbol%3BAcc:MGI:1924122]	-	GO:0005813:centrosome;GO:0005737:cytoplasm;	-	-	-
ENSMUSG00000073627	6437	148	1.19	198	1.75	89	0.64	60	0.56	121.523123575377	0.442604520603141	-1.17590990850572	0.310719332374575	-3.78447616863489	0.000154032665718771	0.00178510328153723	Down	1	86287296	86301513	+	C130036L24Rik	RIKEN cDNA C130036L24 gene [Source:MGI Symbol%3BAcc:MGI:2441877]	-	-	-	-	-
ENSMUSG00000024897	6885	66	0.50	40	0.33	8	0.05	13	0.11	31.0166240146547	0.210697930008285	-2.2467519543508	0.594219149564524	-3.78101573467859	0.000156189801040532	0.00180347470568939	Down	19	23736251	23926960	+	Apba1	amyloid beta (A4) precursor protein binding%2C family  A%2C member 1 [Source:MGI Symbol%3BAcc:MGI:1860297]	GO:0007268:synaptic transmission;GO:0014051:gamma-aminobutyric acid secretion;GO:0014047:glutamate secretion;GO:0001701:in utero embryonic development;GO:0006886:intracellular protein transport;GO:0007626:locomotory behavior;GO:0035264:multicellular organism growth;GO:0065003:macromolecular complex assembly;GO:0010468:regulation of gene expression;GO:2000300:regulation of synaptic vesicle exocytosis;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0043197:dendritic spine;GO:0005794:Golgi apparatus;GO:0016020:membrane;GO:0005634:nucleus;GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;GO:0048787:presynaptic active zone membrane;GO:0032991:macromolecular complex;GO:0008021:synaptic vesicle;	GO:0001540:beta-amyloid binding;GO:0030165:PDZ domain binding;GO:0005546:phosphatidylinositol-4,5-bisphosphate binding;GO:0044877:macromolecular complex binding;	K04531	-
ENSMUSG00000032128	6848	1	0.01	0	0.00	43	0.29	20	0.17	15.6999798416291	64.062194663532	6.00140131816322	1.58757595687638	3.78022940708376	0.00015668392392982	0.00180781887851006	Ups	9	37326965	37344542	-	Robo3	roundabout guidance receptor 3 [Source:MGI Symbol%3BAcc:MGI:1343102]	GO:0007411:axon guidance;GO:0016199:axon midline choice point recognition;GO:0001764:neuron migration;	GO:0030424:axon;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	-	K06755	;ko04360 Axon guidance;
ENSMUSG00000029503	2574	4	0.08	2	0.04	39	0.70	20	0.46	15.9874597940392	10.0618378757397	3.33082194397139	0.882915233534369	3.77252743803942	0.000161602188428364	0.00185479637526986	Ups	5	110487678	110491078	-	P2rx2	purinergic receptor P2X%2C ligand-gated ion channel%2C 2 [Source:MGI Symbol%3BAcc:MGI:2665170]	GO:0048266:behavioral response to pain;GO:0007268:synaptic transmission;GO:0003029:detection of hypoxic conditions in blood by carotid body chemoreceptor signaling;GO:0007528:neuromuscular junction development;GO:0007274:neuromuscular synaptic transmission;GO:0019228:neuronal action potential;GO:0030432:peristalsis;GO:2000300:regulation of synaptic vesicle exocytosis;GO:0033198:response to ATP;GO:0009743:response to carbohydrate;GO:0001666:response to hypoxia;GO:0002931:response to ischemia;GO:0010033:response to organic substance;GO:0007605:sensory perception of sound;GO:0050909:sensory perception of taste;GO:0048741:skeletal muscle fiber development;GO:0014832:urinary bladder smooth muscle contraction;	GO:0016324:apical plasma membrane;GO:0009986:cell surface;GO:0043197:dendritic spine;GO:0016021:integral component of membrane;GO:0005639:integral component of nuclear inner membrane;GO:0005887:integral component of plasma membrane;GO:0016020:membrane;GO:0043025:neuronal cell body;GO:0005886:plasma membrane;GO:0014069:postsynaptic density;GO:0042734:presynaptic membrane;GO:0043235:receptor complex;GO:0043195:terminal bouton;	GO:0005524:ATP binding;GO:0046870:cadmium ion binding;GO:0050897:cobalt ion binding;GO:0005507:copper ion binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0004931:extracellular ATP-gated cation channel activity;GO:0042802:identical protein binding;GO:0015276:ligand-gated ion channel activity;GO:0045340:mercury ion binding;GO:0016151:nickel cation binding;GO:0035091:phosphatidylinositol binding;GO:0044877:macromolecular complex binding;GO:0001614:purinergic nucleotide receptor activity;GO:0008270:zinc ion binding;	K05216	;ko04020 Calcium signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04742 Taste transduction;
ENSMUSG00000027605	10163	139	0.71	107	0.60	56	0.25	42	0.25	84.0810834770058	0.413821052160346	-1.27292105414867	0.33747553830245	-3.77189132152109	0.000162014823706255	0.00185814159065947	Down	2	155359868	155427644	+	Acss2	acyl-CoA synthetase short-chain family member 2 [Source:MGI Symbol%3BAcc:MGI:1890410]	GO:0019413:acetate biosynthetic process;GO:0006085:acetyl-CoA biosynthetic process;GO:0008610:lipid biosynthetic process;GO:0019542:propionate biosynthetic process;GO:0007568:aging;GO:0006750:glutathione biosynthetic process;GO:0043200:response to amino acid;GO:0046686:response to cadmium ion;GO:0031667:response to nutrient levels;GO:0034612:response to tumor necrosis factor;GO:0009410:response to xenobiotic stimulus;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0043231:intracellular membrane-bounded organelle;GO:0005654:nucleoplasm;	GO:0003987:acetate-CoA ligase activity;GO:0005524:ATP binding;GO:0050218:propionate-CoA ligase activity;GO:0043295:glutathione binding;GO:0004363:glutathione synthase activity;GO:0016594:glycine binding;GO:0042802:identical protein binding;GO:0000287:magnesium ion binding;GO:0042277:peptide binding;GO:0042803:protein homodimerization activity;	K01895;K01920	;ko00010 Glycolysis / Gluconeogenesis;ko00620 Pyruvate metabolism;ko00630 Glyoxylate and dicarboxylate metabolism;ko00640 Propanoate metabolism;ko00680 Methane metabolism;ko00720 Carbon fixation pathways in prokaryotes;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko01120 Microbial metabolism in diverse environments;ko01200 Carbon metabolism;;ko00270 Cysteine and methionine metabolism;ko00480 Glutathione metabolism;ko01100 Metabolic pathways;ko01240 Biosynthesis of cofactors;
ENSMUSG00000015222	16456	204	0.64	105	0.36	57	0.16	55	0.20	102.770918037801	0.38171832890562	-1.38941963302245	0.368810234675995	-3.76730226655199	0.00016502115241616	0.00188838384414134	Down	1	66214432	66481742	+	Map2	microtubule-associated protein 2 [Source:MGI Symbol%3BAcc:MGI:97175]	GO:0007409:axonogenesis;GO:0071310:cellular response to organic substance;GO:0021954:central nervous system neuron development;GO:0016358:dendrite development;GO:0030010:establishment of cell polarity;GO:0001578:microtubule bundle formation;GO:0000226:microtubule cytoskeleton organization;GO:0030517:negative regulation of axon extension;GO:0007026:negative regulation of microtubule depolymerization;GO:2000575:negative regulation of microtubule motor activity;GO:0031115:negative regulation of microtubule polymerization;GO:0031175:neuron projection development;GO:1901953:positive regulation of anterograde dense core granule transport;GO:1903744:positive regulation of anterograde synaptic vesicle transport;GO:1903827:regulation of cellular protein localization;GO:1902513:regulation of organelle transport along microtubule;GO:0048813:dendrite morphogenesis;GO:0032355:response to estradiol;GO:0032570:response to progesterone;	GO:0015629:actin cytoskeleton;GO:0097440:apical dendrite;GO:0030424:axon;GO:0043203:axon hillock;GO:0043194:axon initial segment;GO:0097441:basilar dendrite;GO:0097442:CA3 pyramidal cell dendrite;GO:0044297:cell body;GO:0005737:cytoplasm;GO:0030425:dendrite;GO:0032839:dendrite cytoplasm;GO:0044307:dendritic branch;GO:1902737:dendritic filopodium;GO:0044294:dendritic growth cone;GO:0043198:dendritic shaft;GO:0005874:microtubule;GO:0005875:microtubule associated complex;GO:0015630:microtubule cytoskeleton;GO:0043005:neuron projection;GO:0043025:neuronal cell body;GO:0034399:nuclear periphery;GO:0014069:postsynaptic density;GO:0032991:macromolecular complex;GO:1990635:proximal dendrite;GO:0005791:rough endoplasmic reticulum;GO:0032587:ruffle membrane;GO:0005790:smooth endoplasmic reticulum;	GO:0003779:actin binding;GO:0005516:calmodulin binding;GO:0005519:cytoskeletal regulatory protein binding;GO:0002162:dystroglycan binding;GO:0008017:microtubule binding;GO:0019901:protein kinase binding;	K10430	-
ENSMUSG00000009876	788	5	0.33	5	0.36	38	2.22	28	2.12	18.9751230261391	6.82735590109557	2.77132695963594	0.735816083099911	3.76633104832481	0.000165664099076962	0.00189291601732201	Ups	2	152596093	152606957	+	Cox4i2	cytochrome c oxidase subunit 4I2 [Source:MGI Symbol%3BAcc:MGI:2135755]	GO:0071456:cellular response to hypoxia;GO:0006123:mitochondrial electron transport, cytochrome c to oxygen;	GO:0016021:integral component of membrane;GO:0031966:mitochondrial membrane;GO:0005751:mitochondrial respiratory chain complex IV;GO:0005739:mitochondrion;	GO:0004129:cytochrome-c oxidase activity;	K02263	;ko00190 Oxidative phosphorylation;ko01100 Metabolic pathways;ko04260 Cardiac muscle contraction;ko04714 Thermogenesis;ko04932 Non-alcoholic fatty liver disease;ko05010 Alzheimer disease;ko05012 Parkinson disease;ko05014 Amyotrophic lateral sclerosis;ko05016 Huntington disease;ko05020 Prion disease;ko05022 Pathways of neurodegeneration - multiple diseases;
ENSMUSG00000032741	8462	151	0.93	205	1.38	68	0.37	79	0.56	124.454792206621	0.432629466387004	-1.20879616430162	0.321055924865845	-3.76506418564529	0.000166506304814719	0.0018997080937715	Down	5	120672218	120726738	-	Tpcn1	two pore channel 1 [Source:MGI Symbol%3BAcc:MGI:2182472]	GO:0075509:endocytosis involved in viral entry into host cell;GO:0010508:positive regulation of autophagy;GO:0034765:regulation of ion transmembrane transport;GO:0035725:sodium ion transmembrane transport;	GO:0036019:endolysosome;GO:0010008:endosome membrane;GO:0016021:integral component of membrane;GO:0005765:lysosomal membrane;	GO:0042802:identical protein binding;GO:0097682:intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity;GO:0015280:ligand-gated sodium channel activity;GO:0072345:NAADP-sensitive calcium-release channel activity;GO:0080025:phosphatidylinositol-3,5-bisphosphate binding;GO:0042803:protein homodimerization activity;GO:0005245:voltage-gated calcium channel activity;GO:0005248:voltage-gated sodium channel activity;	K16896	;ko04020 Calcium signaling pathway;
ENSMUSG00000111167	3850	57	0.77	41	0.61	7	0.08	12	0.19	28.6345612139765	0.205883528648279	-2.28009968059463	0.605644316016588	-3.76475039936176	0.000166715530321123	0.00190023871985243	Down	9	42053289	42057818	+	Gm39321	predicted gene%2C 39321 [Source:MGI Symbol%3BAcc:MGI:5622206]	-	-	-	-	-
ENSMUSG00000050846	2486	100	2.09	96	2.20	240	4.44	151	3.62	144.845730431542	2.05068265901839	1.0361042535522	0.275349908472966	3.76286398386048	0.000167978571009975	0.00191081855183008	Ups	15	75812801	75821249	+	Zfp623	zinc finger protein 623 [Source:MGI Symbol%3BAcc:MGI:1926084]	GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005634:nucleus;	GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046872:metal ion binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000039853	4338	362	4.33	233	3.06	176	1.87	100	1.37	211.889896196025	0.477561465232543	-1.06624166565652	0.283848869500034	-3.75637101368268	0.00017239506077952	0.00195815249036531	Down	4	46493781	46536141	-	Trim14	tripartite motif-containing 14 [Source:MGI Symbol%3BAcc:MGI:1921985]	GO:0045087:innate immune response;GO:0032897:negative regulation of viral transcription;GO:0010508:positive regulation of autophagy;GO:0051091:positive regulation of sequence-specific DNA binding transcription factor activity;GO:0043123:positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092:positive regulation of NF-kappaB transcription factor activity;GO:0000209:protein polyubiquitination;GO:0016567:protein ubiquitination;GO:0010468:regulation of gene expression;GO:0032880:regulation of protein localization;GO:0046596:regulation of viral entry into host cell;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005741:mitochondrial outer membrane;GO:0005654:nucleoplasm;GO:0045335:phagocytic vesicle;	GO:0042803:protein homodimerization activity;GO:0019901:protein kinase binding;GO:0003713:transcription coactivator activity;GO:0061630:ubiquitin protein ligase activity;GO:0008270:zinc ion binding;	K12004	-
ENSMUSG00000049303	5539	0	0.00	1	0.01	29	0.24	29	0.31	15.0083302208638	60.6744948342944	5.92301828667593	1.58043126449827	3.74772280182414	0.000178447305670615	0.00201792845512774	Ups	19	4495936	4527475	-	Syt12	synaptotagmin XII [Source:MGI Symbol%3BAcc:MGI:2159601]	GO:0017156:calcium ion-dependent exocytosis;GO:0071277:cellular response to calcium ion;GO:0060291:long-term synaptic potentiation;GO:0017158:regulation of calcium ion-dependent exocytosis;GO:0014059:regulation of dopamine secretion;GO:0046928:regulation of neurotransmitter secretion;GO:0048792:calcium ion-independent exocytosis of neurotransmitter;GO:0016192:vesicle-mediated transport;	GO:0070382:exocytic vesicle;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;GO:0098793:presynapse;GO:0030672:synaptic vesicle membrane;	GO:0005509:calcium ion binding;GO:0005544:calcium-dependent phospholipid binding;GO:0030276:clathrin binding;GO:0001786:phosphatidylserine binding;GO:0000149:SNARE binding;GO:0019905:syntaxin binding;	-	-
ENSMUSG00000035713	5288	92	0.90	127	1.37	44	0.38	36	0.41	73.5549213558143	0.377901144531094	-1.40391920686151	0.374810981851364	-3.74567255187375	0.00017991113551422	0.00203298257330512	Down	7	96958587	96981227	-	Usp35	ubiquitin specific peptidase 35 [Source:MGI Symbol%3BAcc:MGI:2685339]	GO:0016579:protein deubiquitination;GO:0006511:ubiquitin-dependent protein catabolic process;	GO:0005829:cytosol;GO:0005634:nucleus;	GO:0004197:cysteine-type endopeptidase activity;GO:0004843:ubiquitin-specific protease activity;	K11854	-
ENSMUSG00000112824	1025	17	0.86	12	0.67	63	2.83	45	2.61	34.0426320927416	3.8578224347296	1.94778674151288	0.520368120010871	3.74309391104165	0.000181768255870693	0.00204943708494206	Ups	10	53939907	53941165	+	Gm47917	predicted gene%2C 47917 [Source:MGI Symbol%3BAcc:MGI:6097168]	-	-	-	-	-
ENSMUSG00000004933	4594	246	2.78	168	2.08	103	1.03	88	1.14	148.182304120772	0.482039996704892	-1.0527752375321	0.281399796299618	-3.74120824313308	0.000183137694090671	0.00206336032416337	Down	10	81088769	81099199	+	Matk	megakaryocyte-associated tyrosine kinase [Source:MGI Symbol%3BAcc:MGI:99259]	-	GO:0005737:cytoplasm;GO:0016020:membrane;	GO:0005524:ATP binding;GO:0004715:non-membrane spanning protein tyrosine kinase activity;GO:0004713:protein tyrosine kinase activity;GO:0004714:transmembrane receptor protein tyrosine kinase activity;	K08888	;ko04722 Neurotrophin signaling pathway;
ENSMUSG00000033900	6671	136	1.06	110	0.94	51	0.35	48	0.43	84.6478479594084	0.420846643761274	-1.24863348295247	0.334006734768158	-3.73834822168833	0.0001852332667492	0.00208543826162425	Down	3	82265351	82302575	+	Map9	microtubule-associated protein 9 [Source:MGI Symbol%3BAcc:MGI:2442208]	GO:0000281:mitotic cytokinesis;GO:0090307:mitotic spindle assembly;GO:0046602:regulation of mitotic centrosome separation;GO:1902412:regulation of mitotic cytokinesis;GO:0060236:regulation of mitotic spindle organization;	GO:0005818:aster;GO:0000235:astral microtubule;GO:0030424:axon;GO:0005737:cytoplasm;GO:0015630:microtubule cytoskeleton;GO:0072686:mitotic spindle;GO:1990023:mitotic spindle midzone;GO:0051233:spindle midzone;	GO:0008017:microtubule binding;	K10434	-
ENSMUSG00000118590	1120	41	1.90	25	1.27	6	0.25	1	0.05	17.5675738429016	0.108180896749694	-3.20848233322457	0.858576777395948	-3.73697777262955	0.000186245380602114	0.00209069302060967	Down	1	84936703	84942293	+	Gm15433	predicted pseudogene 15433 [Source:MGI Symbol%3BAcc:MGI:3705860]	GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005634:nucleus;	GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;	-	-
ENSMUSG00000041420	3173	84	1.37	69	1.24	30	0.44	18	0.34	48.9512164217693	0.323675248825906	-1.62738104679898	0.436656108481619	-3.72691693804045	0.000193836302437621	0.00216638911193767	Down	7	15909015	15920429	+	Meis3	Meis homeobox 3 [Source:MGI Symbol%3BAcc:MGI:108519]	GO:0009887:organ morphogenesis;GO:0007420:brain development;GO:0009880:embryonic pattern specification;GO:0001654:eye development;GO:2001234:negative regulation of apoptotic signaling pathway;GO:0008284:positive regulation of cell proliferation;GO:0051897:positive regulation of protein kinase B signaling;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005634:nucleus;	GO:0003682:chromatin binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043565:sequence-specific DNA binding;	K16671	-
ENSMUSG00000031202	3401	52	0.79	42	0.70	10	0.14	10	0.18	27.836065113925	0.222606684676777	-2.16743117873384	0.58191961200221	-3.72462301326529	0.000195607312465509	0.00217982741958293	Down	X	74615652	74621837	-	Rab39b	RAB39B%2C member RAS oncogene family [Source:MGI Symbol%3BAcc:MGI:1915040]	GO:0006914:autophagy;GO:0015031:protein transport;GO:0032482:Rab protein signal transduction;GO:0010506:regulation of autophagy;GO:0050808:synapse organization;GO:0016192:vesicle-mediated transport;	GO:0030659:cytoplasmic vesicle membrane;GO:0005794:Golgi apparatus;GO:0000139:Golgi membrane;GO:0043005:neuron projection;GO:0005886:plasma membrane;GO:0031982:vesicle;	GO:0005525:GTP binding;GO:0003924:GTPase activity;GO:0031489:myosin V binding;	K07925	;ko04140 Autophagy - animal;ko05014 Amyotrophic lateral sclerosis;ko05022 Pathways of neurodegeneration - multiple diseases;
ENSMUSG00000060716	6718	77	0.60	67	0.57	17	0.12	24	0.21	45.4881694015122	0.300879141632159	-1.73274399920611	0.465244116939164	-3.72437594827811	0.000195798961772527	0.00218028127906797	Down	12	79075937	79128429	+	Plekhh1	pleckstrin homology domain containing%2C family H (with MyTH4 domain) member 1 [Source:MGI Symbol%3BAcc:MGI:2144989]	-	GO:0005856:cytoskeleton;	-	K18441	;ko04072 Phospholipase D signaling pathway;ko04144 Endocytosis;ko05130 Pathogenic Escherichia coli infection;ko05131 Shigellosis;ko05132 Salmonella infection;
ENSMUSG00000073433	1566	0	0.00	0	0.00	22	0.65	10	0.38	7.84696707726889	88.2444303040659	6.46343331801587	1.73673916060124	3.72159128131728	0.000197971275572137	0.00219341874250228	Ups	17	26418157	26426760	-	Arhgdig	Rho GDP dissociation inhibitor (GDI) gamma [Source:MGI Symbol%3BAcc:MGI:108430]	GO:0001835:blastocyst hatching;GO:0032880:regulation of protein localization;GO:0007266:Rho protein signal transduction;	GO:0005829:cytosol;GO:0016020:membrane;GO:0005886:plasma membrane;	GO:0005092:GDP-dissociation inhibitor activity;GO:0005096:GTPase activator activity;GO:0030695:GTPase regulator activity;GO:0005094:Rho GDP-dissociation inhibitor activity;	K12462	;ko04722 Neurotrophin signaling pathway;ko04962 Vasopressin-regulated water reabsorption;
ENSMUSG00000059713	5111	230	2.34	307	3.42	126	1.13	131	1.53	196.3872683812	0.499744274424977	-1.00073805679392	0.2696224093592	-3.71162789907682	0.000205930567935744	0.00225875488463998	Down	4	135139619	135161164	-	Rcan3	regulator of calcineurin 3 [Source:MGI Symbol%3BAcc:MGI:1858220]	GO:0019722:calcium-mediated signaling;	GO:0005737:cytoplasm;GO:0005634:nucleus;	GO:0008597:calcium-dependent protein serine/threonine phosphatase regulator activity;GO:0003676:nucleic acid binding;GO:0019902:phosphatase binding;GO:0031013:troponin I binding;	K17905	-
ENSMUSG00000036256	1209	80	3.44	51	2.40	8	0.30	20	0.99	39.0177549898539	0.230351299275624	-2.11809235953168	0.571309094102194	-3.70743679979442	0.000209367644238452	0.00228990260823996	Down	5	77497087	77555888	-	Igfbp7	insulin-like growth factor binding protein 7 [Source:MGI Symbol%3BAcc:MGI:1352480]	GO:0007155:cell adhesion;GO:0048839:inner ear development;GO:0001558:regulation of cell growth;GO:0009966:regulation of signal transduction;GO:0050810:regulation of steroid biosynthetic process;	GO:0005615:extracellular space;	GO:0005520:insulin-like growth factor binding;	-	-
ENSMUSG00000047293	1638	26	0.82	9	0.31	64	1.80	66	2.40	41.5077538333437	3.92949344651617	1.97434334574059	0.532704504205358	3.7062636605368	0.000210339331400882	0.0022972530681632	Ups	16	58537796	58539433	-	Gpr15	G protein-coupled receptor 15 [Source:MGI Symbol%3BAcc:MGI:1918473]	GO:0007186:G-protein coupled receptor signaling pathway;GO:0072678:T cell migration;GO:0046718:viral entry into host cell;	GO:0005737:cytoplasm;GO:0005768:endosome;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0015026:coreceptor activity;GO:0004930:G-protein coupled receptor activity;GO:0001618:virus receptor activity;	K08403	-
ENSMUSG00000104682	2239	5	0.12	11	0.28	46	0.95	36	0.96	24.5439672872527	5.28536425094688	2.40200290111151	0.648140130311232	3.70599317767607	0.000210563966829441	0.00229806965648587	Ups	5	145229580	145231818	+	Gm42636	predicted gene 42636 [Source:MGI Symbol%3BAcc:MGI:5662773]	-	-	-	-	-
ENSMUSG00000032415	1790	84	2.44	61	1.94	187	4.81	123	4.09	112.34167647452	2.20788004390222	1.14266179133322	0.308629472495534	3.70237418381925	0.000213591289267605	0.00232779589881268	Ups	9	86189359	86347003	-	Ube2cbp	ubiquitin-conjugating enzyme E2C binding protein [Source:MGI Symbol%3BAcc:MGI:1917598]	GO:0043161:proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051865:protein autoubiquitination;GO:0006513:protein monoubiquitination;GO:0000209:protein polyubiquitination;	GO:0005829:cytosol;GO:0005634:nucleus;GO:0000151:ubiquitin ligase complex;	GO:0030332:cyclin binding;GO:0031624:ubiquitin conjugating enzyme binding;GO:0061630:ubiquitin protein ligase activity;GO:0044390:ubiquitin-like protein conjugating enzyme binding;	-	-
ENSMUSG00000018906	6239	2	0.02	2	0.02	35	0.26	17	0.16	13.7591653943223	13.2301669148865	3.72575935799752	1.00663663455385	3.7011958735724	0.000214585744576352	0.00233697287452684	Ups	11	53990921	54022491	+	P4ha2	procollagen-proline%2C 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase)%2C alpha II polypeptide [Source:MGI Symbol%3BAcc:MGI:894286]	GO:0018401:peptidyl-proline hydroxylation to 4-hydroxy-L-proline;	GO:0005829:cytosol;GO:0005783:endoplasmic reticulum;GO:0005788:endoplasmic reticulum lumen;GO:0043231:intracellular membrane-bounded organelle;GO:0005654:nucleoplasm;GO:0016222:procollagen-proline 4-dioxygenase complex;	GO:0005506:iron ion binding;GO:0031418:L-ascorbic acid binding;GO:0004656:procollagen-proline 4-dioxygenase activity;	K00472	;ko00330 Arginine and proline metabolism;ko01100 Metabolic pathways;
ENSMUSG00000031586	6556	298	2.36	219	1.90	158	1.11	92	0.84	186.931433702494	0.497715912156408	-1.00660558365669	0.272196449565124	-3.69808491354278	0.000217232225731097	0.00235969799863378	Down	8	34272671	34419891	-	Rbpms	RNA binding protein gene with multiple splicing [Source:MGI Symbol%3BAcc:MGI:1334446]	GO:0010862:positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0060391:positive regulation of SMAD protein import into nucleus;GO:0006979:response to oxidative stress;GO:0006396:RNA processing;	GO:0010494:cytoplasmic stress granule;GO:0005829:cytosol;GO:0005654:nucleoplasm;GO:0000932:cytoplasmic mRNA processing body;	GO:0003729:mRNA binding;GO:0008143:poly(A) binding;GO:0042803:protein homodimerization activity;GO:0003723:RNA binding;GO:0003713:transcription coactivator activity;	-	-
ENSMUSG00000014837	4045	162	2.08	161	2.27	78	0.89	71	1.05	116.13305386603	0.480786070163011	-1.05653299750272	0.285918265457261	-3.69522736091392	0.000219690108881047	0.00237904528925281	Down	8	106007041	106016496	-	4931428F04Rik	RIKEN cDNA 4931428F04 gene [Source:MGI Symbol%3BAcc:MGI:1921606]	-	-	-	-	-
ENSMUSG00000022696	5623	95	0.88	84	0.85	39	0.32	24	0.25	59.0322800702284	0.362942513838249	-1.46218703583475	0.396203157353001	-3.69049819189603	0.000223815279840768	0.00240503398814179	Down	16	44060543	44153559	-	Sidt1	SID1 transmembrane family%2C member 1 [Source:MGI Symbol%3BAcc:MGI:2443155]	GO:0050658:RNA transport;	GO:0016021:integral component of membrane;GO:0005764:lysosome;GO:0005886:plasma membrane;	GO:0015485:cholesterol binding;GO:0003725:double-stranded RNA binding;GO:0051033:RNA transmembrane transporter activity;	-	-
ENSMUSG00000021263	2583	96	1.93	103	2.27	47	0.84	15	0.35	63.336605919998	0.314075936171057	-1.67081468388287	0.453470696180241	-3.68450419830165	0.000229148249024599	0.00245545719814339	Down	12	108644970	108668570	-	Degs2	delta(4)-desaturase%2C sphingolipid 2 [Source:MGI Symbol%3BAcc:MGI:1917309]	GO:0046513:ceramide biosynthetic process;GO:0006667:sphinganine metabolic process;GO:0030148:sphingolipid biosynthetic process;	GO:0005789:endoplasmic reticulum membrane;GO:0016021:integral component of membrane;	GO:0042284:sphingolipid delta-4 desaturase activity;GO:0000170:sphingosine hydroxylase activity;	K04712	;ko00600 Sphingolipid metabolism;ko01100 Metabolic pathways;ko04071 Sphingolipid signaling pathway;
ENSMUSG00000097134	2513	66	1.36	56	1.27	11	0.20	19	0.45	37.3739613654021	0.261208479332458	-1.93672636457143	0.525783505197476	-3.68350536946576	0.000230048435785246	0.00246166274552056	Down	10	66748268	66756037	-	1110002J07Rik	RIKEN cDNA 1110002J07 gene [Source:MGI Symbol%3BAcc:MGI:1915738]	-	-	-	-	-
ENSMUSG00000033769	15133	146	0.50	157	0.59	75	0.23	62	0.24	108.159592525462	0.469302730440646	-1.09140924078217	0.296316791418004	-3.68325141332458	0.000230277840407217	0.00246239916653017	Down	6	84595469	85046495	-	Exoc6b	exocyst complex component 6B [Source:MGI Symbol%3BAcc:MGI:1923164]	GO:0006887:exocytosis;GO:0006893:Golgi to plasma membrane transport;GO:0006886:intracellular protein transport;GO:0090522:vesicle tethering involved in exocytosis;	GO:0000145:exocyst;GO:0016020:membrane;	-	-	-
ENSMUSG00000048603	4501	63	0.73	58	0.73	22	0.22	10	0.13	37.181477512748	0.270680650002123	-1.88533633679059	0.51214710638928	-3.68123984939117	0.000232102534029594	0.00247500713269109	Down	13	98452930	98463737	+	Gm9828	predicted gene 9828 [Source:MGI Symbol%3BAcc:MGI:3642913]	-	-	-	-	-
ENSMUSG00000034684	5197	7	0.07	8	0.09	44	0.39	32	0.37	22.690883848521	5.23364663773288	2.3878165206412	0.649037057393997	3.67901415402801	0.000234137275014296	0.00248805334377631	Ups	9	107558699	107587674	-	Sema3f	sema domain%2C immunoglobulin domain (Ig)%2C short basic domain%2C secreted%2C (semaphorin) 3F [Source:MGI Symbol%3BAcc:MGI:1096347]	GO:0048846:axon extension involved in axon guidance;GO:0007411:axon guidance;GO:0021785:branchiomotor neuron axon guidance;GO:0021612:facial nerve structural organization;GO:0040011:locomotion;GO:0050919:negative chemotaxis;GO:0048843:negative regulation of axon extension involved in axon guidance;GO:0021675:nerve development;GO:0001755:neural crest cell migration;GO:1901166:neural crest cell migration involved in autonomic nervous system development;GO:0030335:positive regulation of cell migration;GO:0071526:semaphorin-plexin signaling pathway;GO:1902287:semaphorin-plexin signaling pathway involved in axon guidance;GO:1902285:semaphorin-plexin signaling pathway involved in neuron projection guidance;GO:0061549:sympathetic ganglion development;GO:0097490:sympathetic neuron projection extension;GO:0097491:sympathetic neuron projection guidance;GO:0021637:trigeminal nerve structural organization;GO:0036486:ventral trunk neural crest cell migration;	GO:0005615:extracellular space;GO:0005887:integral component of plasma membrane;	GO:0045499:chemorepellent activity;GO:0030215:semaphorin receptor binding;	K06840	;ko04360 Axon guidance;
ENSMUSG00000057614	3135	0	0.00	0	0.00	19	0.28	11	0.21	7.43664227206058	83.5127612379825	6.38392476155261	1.74180466989101	3.66512093572011	0.000247221733225844	0.00260655231460237	Ups	5	18470133	18565353	-	Gnai1	guanine nucleotide binding protein (G protein)%2C alpha inhibiting 1 [Source:MGI Symbol%3BAcc:MGI:95771]	GO:0007188:adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0007049:cell cycle;GO:0051301:cell division;GO:0007186:G-protein coupled receptor signaling pathway;GO:0050805:negative regulation of synaptic transmission;GO:0043949:regulation of cAMP-mediated signaling;GO:0060236:regulation of mitotic spindle organization;	GO:0005813:centrosome;GO:0005737:cytoplasm;GO:0005834:heterotrimeric G-protein complex;GO:0016020:membrane;GO:0045121:membrane raft;GO:0030496:midbody;GO:0005634:nucleus;GO:0005886:plasma membrane;GO:0032991:macromolecular complex;	GO:0001664:G-protein coupled receptor binding;GO:0031821:G-protein coupled serotonin receptor binding;GO:0031683:G-protein beta/gamma-subunit complex binding;GO:0019003:GDP binding;GO:0005525:GTP binding;GO:0032794:GTPase activating protein binding;GO:0003924:GTPase activity;GO:0000287:magnesium ion binding;	K04630	;ko04015 Rap1 signaling pathway;ko04022 cGMP-PKG signaling pathway;ko04024 cAMP signaling pathway;ko04062 Chemokine signaling pathway;ko04071 Sphingolipid signaling pathway;ko04113 Meiosis - yeast;ko04261 Adrenergic signaling in cardiomyocytes;ko04360 Axon guidance;ko04371 Apelin signaling pathway;ko04540 Gap junction;ko04611 Platelet activation;ko04670 Leukocyte transendothelial migration;ko04713 Circadian entrainment;ko04723 Retrograde endocannabinoid signaling;ko04724 Glutamatergic synapse;ko04725 Cholinergic synapse;ko04726 Serotonergic synapse;ko04727 GABAergic synapse;ko04728 Dopaminergic synapse;ko04730 Long-term depression;ko04914 Progesterone-mediated oocyte maturation;ko04915 Estrogen signaling pathway;ko04916 Melanogenesis;ko04921 Oxytocin signaling pathway;ko04923 Regulation of lipolysis in adipocytes;ko04924 Renin secretion;ko04926 Relaxin signaling pathway;ko04928 Parathyroid hormone synthesis, secretion and action;ko04934 Cushing syndrome;ko04935 Growth hormone synthesis, secretion and action;ko04971 Gastric acid secretion;ko05012 Parkinson disease;ko05030 Cocaine addiction;ko05032 Morphine addiction;ko05034 Alcoholism;ko05133 Pertussis;ko05142 Chagas disease;ko05145 Toxoplasmosis;ko05163 Human cytomegalovirus infection;ko05170 Human immunodeficiency virus 1 infection;ko05200 Pathways in cancer;
ENSMUSG00000018916	800	5	0.32	1	0.07	32	1.84	24	1.79	15.4814998764876	9.72940890788928	3.2823521594195	0.895793182863291	3.66418524075821	0.000248127165770269	0.00261317442302288	Ups	11	54138097	54140493	-	Csf2	colony stimulating factor 2 (granulocyte-macrophage) [Source:MGI Symbol%3BAcc:MGI:1339752]	GO:0097011:cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:0097028:dendritic cell differentiation;GO:0001892:embryonic placenta development;GO:0042045:epithelial fluid transport;GO:0001821:histamine secretion;GO:0006955:immune response;GO:0042116:macrophage activation;GO:0030225:macrophage differentiation;GO:0030224:monocyte differentiation;GO:0030099:myeloid cell differentiation;GO:0043011:myeloid dendritic cell differentiation;GO:2001240:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0045892:negative regulation of transcription, DNA-templated;GO:0030223:neutrophil differentiation;GO:0008284:positive regulation of cell proliferation;GO:0010628:positive regulation of gene expression;GO:0032747:positive regulation of interleukin-23 production;GO:0010744:positive regulation of macrophage derived foam cell differentiation;GO:0071803:positive regulation of podosome assembly;GO:0042531:positive regulation of tyrosine phosphorylation of STAT protein;GO:0042127:regulation of cell proliferation;GO:0045187:regulation of circadian sleep/wake cycle, sleep;GO:0010468:regulation of gene expression;	GO:0005615:extracellular space;GO:0043231:intracellular membrane-bounded organelle;	GO:0005125:cytokine activity;GO:0005129:granulocyte macrophage colony-stimulating factor receptor binding;GO:0008083:growth factor activity;	K05427	;ko04060 Cytokine-cytokine receptor interaction;ko04630 JAK-STAT signaling pathway;ko04640 Hematopoietic cell lineage;ko04650 Natural killer cell mediated cytotoxicity;ko04657 IL-17 signaling pathway;ko04660 T cell receptor signaling pathway;ko04664 Fc epsilon RI signaling pathway;ko04668 TNF signaling pathway;ko05131 Shigellosis;ko05146 Amoebiasis;ko05166 Human T-cell leukemia virus 1 infection;ko05167 Kaposi sarcoma-associated herpesvirus infection;ko05171 Coronavirus disease - COVID-19;ko05202 Transcriptional misregulation in cancer;ko05221 Acute myeloid leukemia;ko05323 Rheumatoid arthritis;
ENSMUSG00000019312	3365	52	0.80	87	1.47	17	0.23	20	0.35	43.4668359623377	0.277767876154786	-1.84804833355213	0.505622280832356	-3.65499781874697	0.000257184164549105	0.00269530870989794	Down	11	98337220	98346199	+	Grb7	growth factor receptor bound protein 7 [Source:MGI Symbol%3BAcc:MGI:102683]	GO:0017148:negative regulation of translation;GO:0030335:positive regulation of cell migration;GO:0007165:signal transduction;GO:0034063:stress granule assembly;	GO:0042995:cell projection;GO:0010494:cytoplasmic stress granule;GO:0005829:cytosol;GO:0005925:focal adhesion;GO:0005886:plasma membrane;	GO:0042802:identical protein binding;GO:0035091:phosphatidylinositol binding;GO:0019901:protein kinase binding;GO:0003723:RNA binding;	-	-
ENSMUSG00000000811	2836	118	2.16	65	1.30	228	3.70	161	3.38	141.387632437409	2.20775329374269	1.14257896659998	0.312619918229863	3.65485018699246	0.000257332199771135	0.00269530870989794	Ups	6	89620970	89652511	+	Txnrd3	thioredoxin reductase 3 [Source:MGI Symbol%3BAcc:MGI:2386711]	GO:0001825:blastocyst formation;GO:0030154:cell differentiation;GO:0045454:cell redox homeostasis;GO:0006749:glutathione metabolic process;GO:0007283:spermatogenesis;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005783:endoplasmic reticulum;GO:0005739:mitochondrion;GO:0005654:nucleoplasm;	GO:0050660:flavin adenine dinucleotide binding;GO:0097573:glutathione oxidoreductase activity;GO:0004791:thioredoxin-disulfide reductase activity;	K00384	;ko00450 Selenocompound metabolism;
ENSMUSG00000089984	2512	28	0.58	44	1.00	8	0.15	2	0.05	19.9821303154158	0.14026308578567	-2.83379272214656	0.77642142540068	-3.64981262680142	0.000262431669179232	0.00273848781073914	Down	5	137610765	137627264	-	Fbxo24	F-box protein 24 [Source:MGI Symbol%3BAcc:MGI:1918426]	-	-	-	K10304	-
ENSMUSG00000071052	792	97	6.36	101	7.26	254	14.76	146	10.98	147.207856880034	2.06695152261217	1.04750455281408	0.287202272822481	3.64727111147041	0.000265040230482762	0.0027590813945843	Ups	17	58145425	58146216	-	Rpl7a-ps5	ribosomal protein L7A%2C pseudogene 5 [Source:MGI Symbol%3BAcc:MGI:3643553]	GO:0000470:maturation of LSU-rRNA;	GO:0005829:cytosol;GO:0022625:cytosolic large ribosomal subunit;GO:0022626:cytosolic ribosome;GO:0016020:membrane;GO:0005730:nucleolus;GO:0042788:polysomal ribosome;GO:0005840:ribosome;GO:0045202:synapse;	GO:0003723:RNA binding;GO:0003735:structural constituent of ribosome;	K02936	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000110615	1863	18	0.50	13	0.40	0	0.00	0	0.00	7.48994098058905	0.0124333148276685	-6.32964520731168	1.7362761120778	-3.64552916628969	0.000266842147131652	0.00276808603230729	Down	8	124675529	124685674	+	Gm45890	predicted gene 45890 [Source:MGI Symbol%3BAcc:MGI:5805005]	-	-	-	-	-
ENSMUSG00000020937	3393	43	0.66	49	0.82	13	0.18	7	0.12	27.3124924264826	0.22315577823945	-2.16387693167885	0.593597581401823	-3.64536008817405	0.000267017656339296	0.00276808603230729	Down	11	102961130	102992484	-	Plcd3	phospholipase C%2C delta 3 [Source:MGI Symbol%3BAcc:MGI:107451]	GO:0001525:angiogenesis;GO:0060716:labyrinthine layer blood vessel development;GO:0016042:lipid catabolic process;GO:0048015:phosphatidylinositol-mediated signaling;GO:0042127:regulation of cell proliferation;	GO:0032154:cleavage furrow;GO:0005829:cytosol;GO:0016020:membrane;	GO:0046872:metal ion binding;GO:0004435:phosphatidylinositol phospholipase C activity;	K05857	;ko00562 Inositol phosphate metabolism;ko01100 Metabolic pathways;ko04020 Calcium signaling pathway;ko04070 Phosphatidylinositol signaling system;ko04919 Thyroid hormone signaling pathway;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05131 Shigellosis;
ENSMUSG00000042745	1160	0	0.00	0	0.00	20	0.79	10	0.51	7.38734341844766	83.0319385613385	6.37559447641866	1.74910275839813	3.6450657034339	0.000267323496616152	0.00276808603230729	Ups	2	152578171	152579330	+	Id1	inhibitor of DNA binding 1%2C HLH protein [Source:MGI Symbol%3BAcc:MGI:96396]	GO:0001525:angiogenesis;GO:0043534:blood vessel endothelial cell migration;GO:0048514:blood vessel morphogenesis;GO:0007420:brain development;GO:0030154:cell differentiation;GO:0036164:cell-abiotic substrate adhesion;GO:1903351:cellular response to dopamine;GO:0071364:cellular response to epidermal growth factor stimulus;GO:1990090:cellular response to nerve growth factor stimulus;GO:1901653:cellular response to peptide;GO:0032922:circadian regulation of gene expression;GO:0043066:negative regulation of apoptotic process;GO:0050774:negative regulation of dendrite morphogenesis;GO:0043392:negative regulation of DNA binding;GO:0043433:negative regulation of sequence-specific DNA binding transcription factor activity;GO:0045602:negative regulation of endothelial cell differentiation;GO:0032091:negative regulation of protein binding;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0010621:negative regulation of transcription by transcription factor localization;GO:0045892:negative regulation of transcription, DNA-templated;GO:0030182:neuron differentiation;GO:0032233:positive regulation of actin filament bundle assembly;GO:0050679:positive regulation of epithelial cell proliferation;GO:0010628:positive regulation of gene expression;GO:1901342:regulation of vasculature development;GO:0007179:transforming growth factor beta receptor signaling pathway;GO:0030509:BMP signaling pathway;GO:0007623:circadian rhythm;GO:0032963:collagen metabolic process;GO:0001886:endothelial cell morphogenesis;GO:0007507:heart development;GO:0060425:lung morphogenesis;GO:0060426:lung vasculature development;GO:0010629:negative regulation of gene expression;GO:0045668:negative regulation of osteoblast differentiation;GO:0031648:protein destabilization;GO:0045765:regulation of angiogenesis;GO:0043408:regulation of MAPK cascade;GO:0046677:response to antibiotic;	GO:0005813:centrosome;GO:0005794:Golgi apparatus;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0005737:cytoplasm;	GO:0042802:identical protein binding;GO:0070628:proteasome binding;GO:0008022:protein C-terminus binding;GO:0046983:protein dimerization activity;GO:0047485:protein N-terminus binding;GO:0043621:protein self-association;	K04680	;ko04015 Rap1 signaling pathway;ko04350 TGF-beta signaling pathway;ko04390 Hippo signaling pathway;ko04550 Signaling pathways regulating pluripotency of stem cells;
ENSMUSG00000033475	1131	71	3.26	61	3.07	205	8.34	102	5.37	107.550817345892	2.37060807948547	1.24525716913822	0.341849492079425	3.64270592173032	0.000269786998786014	0.00278580056524225	Ups	17	47997571	47999311	-	Tomm6	translocase of outer mitochondrial membrane 6 [Source:MGI Symbol%3BAcc:MGI:1913369]	GO:0015031:protein transport;	GO:0005742:mitochondrial outer membrane translocase complex;GO:0005739:mitochondrion;	-	K17772	-
ENSMUSG00000061410	7780	5	0.03	1	0.01	27	0.16	28	0.21	15.4488834615287	9.68437103206854	3.27565835359037	0.899708230931207	3.64080069624353	0.000271791474558664	0.00280272392123911	Ups	8	122325442	122379640	-	Zcchc14	zinc finger%2C CCHC domain containing 14 [Source:MGI Symbol%3BAcc:MGI:2159407]	-	-	GO:0003676:nucleic acid binding;GO:0035091:phosphatidylinositol binding;GO:0008270:zinc ion binding;	-	-
ENSMUSG00000055538	4557	135	1.54	142	1.77	58	0.59	61	0.80	97.6355876568356	0.449592300697441	-1.15331076537997	0.3168935691985	-3.63942622217603	0.00027324620854153	0.00281205192065491	Down	14	25712066	25769463	-	Zcchc24	zinc finger%2C CCHC domain containing 24 [Source:MGI Symbol%3BAcc:MGI:1919168]	-	-	GO:0003676:nucleic acid binding;GO:0008270:zinc ion binding;GO:0003723:RNA binding;	-	-
ENSMUSG00000026797	4997	167	1.73	164	1.87	90	0.83	67	0.80	119.702372750193	0.491126609332407	-1.02583310474689	0.281885923414164	-3.63917819067424	0.000273509499425666	0.00281236140779227	Down	2	32677614	32737257	-	Stxbp1	syntaxin binding protein 1 [Source:MGI Symbol%3BAcc:MGI:107363]	GO:0007412:axon target recognition;GO:0071346:cellular response to interferon-gamma;GO:0003006:developmental process involved in reproduction;GO:0006887:exocytosis;GO:0006886:intracellular protein transport;GO:0060292:long term synaptic depression;GO:0043524:negative regulation of neuron apoptotic process;GO:0031333:negative regulation of protein complex assembly;GO:0032229:negative regulation of synaptic transmission, GABAergic;GO:0007274:neuromuscular synaptic transmission;GO:0007269:neurotransmitter secretion;GO:0070527:platelet aggregation;GO:0002576:platelet degranulation;GO:0045956:positive regulation of calcium ion-dependent exocytosis;GO:0045921:positive regulation of exocytosis;GO:1903296:positive regulation of glutamate secretion, neurotransmission;GO:0043306:positive regulation of mast cell degranulation;GO:0072659:protein localization to plasma membrane;GO:0050821:protein stabilization;GO:2000367:regulation of acrosomal vesicle exocytosis;GO:0010807:regulation of synaptic vesicle priming;GO:0031338:regulation of vesicle fusion;GO:0032355:response to estradiol;GO:0035493:SNARE complex assembly;GO:0031629:synaptic vesicle fusion to presynaptic membrane;GO:0016188:synaptic vesicle maturation;GO:0016082:synaptic vesicle priming;GO:0006904:vesicle docking involved in exocytosis;GO:0016192:vesicle-mediated transport;	GO:0030424:axon;GO:0005737:cytoplasm;GO:0005856:cytoskeleton;GO:0005829:cytosol;GO:0005739:mitochondrion;GO:0043209:myelin sheath;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0048471:perinuclear region of cytoplasm;GO:0045335:phagocytic vesicle;GO:0005886:plasma membrane;GO:0031091:platelet alpha granule;GO:0098794:postsynapse;GO:0098793:presynapse;GO:0048787:presynaptic active zone membrane;GO:0032991:macromolecular complex;GO:0030141:secretory granule;	GO:0042802:identical protein binding;GO:0043274:phospholipase binding;GO:0019904:protein domain specific binding;GO:0019901:protein kinase binding;GO:0047485:protein N-terminus binding;GO:0000149:SNARE binding;GO:0019905:syntaxin binding;GO:0017075:syntaxin-1 binding;	K15292	;ko04721 Synaptic vesicle cycle;
ENSMUSG00000053746	1135	46	2.10	35	1.75	132	5.35	75	3.94	70.8531160776244	2.62256543781219	1.39097877113593	0.382349579380515	3.63797646486128	0.000274788528019576	0.00282155469524057	Ups	2	32665798	32667609	+	Ptrh1	peptidyl-tRNA hydrolase 1 homolog [Source:MGI Symbol%3BAcc:MGI:1913779]	-	GO:0005739:mitochondrion;	GO:0004045:aminoacyl-tRNA hydrolase activity;	K01056	-
ENSMUSG00000049709	4504	133	1.53	141	1.78	67	0.68	54	0.71	97.028826947089	0.458063411536412	-1.12638076473848	0.309710102458447	-3.63688738532384	0.000275952504221918	0.00283040515032702	Down	7	108521059	108529385	-	Nlrp10	NLR family%2C pyrin domain containing 10 [Source:MGI Symbol%3BAcc:MGI:2444084]	GO:0002250:adaptive immune response;GO:0050832:defense response to fungus;GO:0050829:defense response to Gram-negative bacterium;GO:0006954:inflammatory response;GO:0045087:innate immune response;GO:1900426:positive regulation of defense response to bacterium;GO:0050729:positive regulation of inflammatory response;GO:0032730:positive regulation of interleukin-1 alpha production;GO:0032755:positive regulation of interleukin-6 production;GO:0032757:positive regulation of interleukin-8 production;GO:0002827:positive regulation of T-helper 1 type immune response;GO:2000318:positive regulation of T-helper 17 type immune response;	GO:0005737:cytoplasm;GO:0019897:extrinsic component of plasma membrane;	GO:0005524:ATP binding;GO:0016887:ATPase activity;GO:0003924:GTPase activity;	-	-
ENSMUSG00000030494	6304	5	0.04	8	0.07	50	0.36	25	0.24	21.644265010816	5.85859966426492	2.55055586962285	0.702669155132828	3.6298104890355	0.000283629379287589	0.00289920830602796	Ups	7	35033595	35091714	+	Rhpn2	rhophilin%2C Rho GTPase binding protein 2 [Source:MGI Symbol%3BAcc:MGI:1289234]	GO:0003094:glomerular filtration;GO:0051497:negative regulation of stress fiber assembly;GO:0007165:signal transduction;	GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;	-	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000033066	8057	100	0.64	75	0.53	29	0.17	31	0.23	57.6210278973361	0.360194349047365	-1.47315254736137	0.406775809985911	-3.6215342977558	0.000292860969388616	0.00297005959299275	Down	11	67345917	67575800	+	Gas7	growth arrest specific 7 [Source:MGI Symbol%3BAcc:MGI:1202388]	GO:0051017:actin filament bundle assembly;GO:0030041:actin filament polymerization;GO:0030182:neuron differentiation;GO:0048812:neuron projection morphogenesis;GO:0008360:regulation of cell shape;	GO:0005884:actin filament;GO:0005737:cytoplasm;GO:0005886:plasma membrane;GO:0001726:ruffle;	GO:0051015:actin filament binding;GO:0042802:identical protein binding;	K18618	-
ENSMUSG00000038648	7283	204	1.45	184	1.44	46	0.29	94	0.77	130.844916013801	0.388307900866594	-1.36472703295364	0.377339516810713	-3.61670848706321	0.000298373008222504	0.00301201560769182	Down	6	37304190	37419081	-	Creb3l2	cAMP responsive element binding protein 3-like 2 [Source:MGI Symbol%3BAcc:MGI:2442695]	GO:0051216:cartilage development;GO:0002062:chondrocyte differentiation;GO:0006888:ER to Golgi vesicle-mediated transport;GO:0030968:endoplasmic reticulum unfolded protein response;GO:0010628:positive regulation of gene expression;GO:0010976:positive regulation of neuron projection development;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-templated;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0034976:response to endoplasmic reticulum stress;GO:0009611:response to wounding;	GO:0000785:chromatin;GO:0005829:cytosol;GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0000139:Golgi membrane;GO:0016021:integral component of membrane;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0097038:perinuclear endoplasmic reticulum;	GO:0035497:cAMP response element binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000976:transcription regulatory region sequence-specific DNA binding;	K09048	;ko04022 cGMP-PKG signaling pathway;ko04024 cAMP signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04152 AMPK signaling pathway;ko04211 Longevity regulating pathway;ko04261 Adrenergic signaling in cardiomyocytes;ko04668 TNF signaling pathway;ko04714 Thermogenesis;ko04725 Cholinergic synapse;ko04728 Dopaminergic synapse;ko04911 Insulin secretion;ko04915 Estrogen signaling pathway;ko04916 Melanogenesis;ko04918 Thyroid hormone synthesis;ko04922 Glucagon signaling pathway;ko04925 Aldosterone synthesis and secretion;ko04926 Relaxin signaling pathway;ko04927 Cortisol synthesis and secretion;ko04928 Parathyroid hormone synthesis, secretion and action;ko04931 Insulin resistance;ko04934 Cushing syndrome;ko04935 Growth hormone synthesis, secretion and action;ko04962 Vasopressin-regulated water reabsorption;ko05016 Huntington disease;ko05020 Prion disease;ko05030 Cocaine addiction;ko05031 Amphetamine addiction;ko05034 Alcoholism;ko05161 Hepatitis B;ko05163 Human cytomegalovirus infection;ko05165 Human papillomavirus infection;ko05166 Human T-cell leukemia virus 1 infection;ko05203 Viral carcinogenesis;ko05215 Prostate cancer;
ENSMUSG00000104156	2006	168	4.35	127	3.60	77	1.77	53	1.57	103.808764591912	0.45649519049971	-1.1313284344123	0.312911914929356	-3.61548531850479	0.000299785465510413	0.00302229475880123	Down	5	123272002	123275758	+	Gm38102	predicted gene%2C 38102 [Source:MGI Symbol%3BAcc:MGI:5611330]	-	-	-	-	-
ENSMUSG00000106383	1742	73	2.18	110	3.59	28	0.74	32	1.09	60.0373814149657	0.342484682733179	-1.54588862838802	0.427942663884352	-3.61237324261219	0.000303407429306692	0.00305078657114021	Down	3	95546615	95548356	+	E330034L11Rik	RIKEN cDNA E330034L11 gene [Source:MGI Symbol%3BAcc:MGI:3026962]	-	-	-	-	-
ENSMUSG00000020604	3906	59	0.78	67	0.98	21	0.25	16	0.24	39.9290959579315	0.303910101722533	-1.71828346523021	0.475717261889605	-3.61198468688099	0.00030386251337947	0.00305336027533473	Down	11	109364200	109464156	+	Arsg	arylsulfatase G [Source:MGI Symbol%3BAcc:MGI:1921258]	GO:0006790:sulfur compound metabolic process;	GO:0005783:endoplasmic reticulum;GO:0005615:extracellular space;GO:0005764:lysosome;	GO:0004065:arylsulfatase activity;GO:0046872:metal ion binding;	K12381;K08183	-
ENSMUSG00000062609	6313	0	0.00	0	0.00	13	0.09	15	0.14	7.17421402769104	80.1958391837898	6.32545548188387	1.7516580951498	3.61112451076985	0.000304872243267183	0.00306150031320169	Ups	16	95058417	95101119	+	Kcnj15	potassium inwardly-rectifying channel%2C subfamily J%2C member 15 [Source:MGI Symbol%3BAcc:MGI:1310000]	GO:1990573:potassium ion import across plasma membrane;GO:0006813:potassium ion transport;GO:0034765:regulation of ion transmembrane transport;	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0005242:inward rectifier potassium channel activity;GO:0005267:potassium channel activity;	K05008	;ko04971 Gastric acid secretion;
ENSMUSG00000032086	6348	232	1.90	208	1.86	76	0.55	114	1.07	155.915351665206	0.459413381131768	-1.12213521681476	0.310764706871046	-3.61088370720425	0.000305155476340271	0.00306233905379693	Down	9	45749878	45775697	+	Bace1	beta-site APP cleaving enzyme 1 [Source:MGI Symbol%3BAcc:MGI:1346542]	GO:0042987:amyloid precursor protein catabolic process;GO:0034205:beta-amyloid formation;GO:0050435:beta-amyloid metabolic process;GO:0071280:cellular response to copper ion;GO:0071287:cellular response to manganese ion;GO:0050966:detection of mechanical stimulus involved in sensory perception of pain;GO:0006509:membrane protein ectodomain proteolysis;GO:0007613:memory;GO:0050804:regulation of synaptic transmission;GO:0043525:positive regulation of neuron apoptotic process;GO:0060134:prepulse inhibition;GO:0016485:protein processing;GO:0006508:proteolysis;GO:0048167:regulation of synaptic plasticity;GO:2000300:regulation of synaptic vesicle exocytosis;GO:0010288:response to lead ion;GO:0009314:response to radiation;	GO:0030424:axon;GO:0009986:cell surface;GO:0031410:cytoplasmic vesicle;GO:0030659:cytoplasmic vesicle membrane;GO:0030425:dendrite;GO:0005769:early endosome;GO:0005783:endoplasmic reticulum;GO:0005768:endosome;GO:0005794:Golgi apparatus;GO:0005887:integral component of plasma membrane;GO:0005770:late endosome;GO:0005764:lysosome;GO:0016020:membrane;GO:0045121:membrane raft;GO:0005771:multivesicular body;GO:0043025:neuronal cell body;GO:0005886:plasma membrane;GO:0098793:presynapse;GO:0055037:recycling endosome;GO:0008021:synaptic vesicle;GO:0005802:trans-Golgi network;GO:0016021:integral component of membrane;	GO:0001540:beta-amyloid binding;GO:0004190:aspartic-type endopeptidase activity;GO:0004175:endopeptidase activity;GO:0019899:enzyme binding;GO:0008233:peptidase activity;	K04521	;ko05010 Alzheimer disease;
ENSMUSG00000044948	7059	25	0.18	33	0.27	120	0.78	56	0.47	57.3401085801624	3.07316111719913	1.61972340535942	0.448606282102873	3.61056781854872	0.000305527398098429	0.00306406613632525	Ups	19	47725296	47907726	-	Cfap43	cilia and flagella associated protein 43 [Source:MGI Symbol%3BAcc:MGI:1289258]	GO:0007420:brain development;GO:0060271:cilium morphogenesis;GO:0003351:epithelial cilium movement;GO:0030317:sperm motility;GO:0044458:motile cilium assembly;GO:0003356:regulation of cilium beat frequency;GO:0007288:sperm axoneme assembly;	GO:0005930:axoneme;GO:0005576:extracellular region;	-	-	-
ENSMUSG00000117297	219	114	27.02	132	34.30	60	12.61	43	11.69	85.6224375719585	0.432209078809112	-1.21019871770309	0.335208314480235	-3.61028848457889	0.000305856634598294	0.00306536316008512	Down	17	57375260	57376360	-	Gm49888	predicted gene%2C 49888 [Source:MGI Symbol%3BAcc:MGI:6270574]	-	-	-	-	-
ENSMUSG00000001281	2770	157	2.94	164	3.37	93	1.54	45	0.97	111.892798046888	0.438212611931985	-1.19029708862884	0.329989494135854	-3.60707570932183	0.000309667327315925	0.00309344547039895	Down	15	102124430	102140379	-	Itgb7	integrin beta 7 [Source:MGI Symbol%3BAcc:MGI:96616]	GO:0033627:cell adhesion mediated by integrin;GO:0016477:cell migration;GO:0007160:cell-matrix adhesion;GO:0003366:cell-matrix adhesion involved in ameboidal cell migration;GO:0034113:heterotypic cell-cell adhesion;GO:0007229:integrin-mediated signaling pathway;GO:0050900:leukocyte migration;GO:0050901:leukocyte tethering or rolling;GO:0043113:receptor clustering;GO:0034446:substrate adhesion-dependent cell spreading;GO:0072678:T cell migration;	GO:0009986:cell surface;GO:0005925:focal adhesion;GO:0034669:integrin alpha4-beta7 complex;GO:0043235:receptor complex;	GO:0050839:cell adhesion molecule binding;GO:0005178:integrin binding;GO:0038023:signaling receptor activity;	K06590	;ko04151 PI3K-Akt signaling pathway;ko04510 Focal adhesion;ko04512 ECM-receptor interaction;ko04514 Cell adhesion molecules;ko04672 Intestinal immune network for IgA production;ko04810 Regulation of actin cytoskeleton;ko05165 Human papillomavirus infection;ko05202 Transcriptional misregulation in cancer;ko05410 Hypertrophic cardiomyopathy;ko05412 Arrhythmogenic right ventricular cardiomyopathy;ko05414 Dilated cardiomyopathy;
ENSMUSG00000032356	11063	0	0.00	0	0.00	19	0.08	10	0.05	7.15753158903704	80.4246684521708	6.32956617831875	1.75626539254235	3.60399185977021	0.000313366874452292	0.00312023873561782	Ups	9	89791961	89909030	+	Rasgrf1	RAS protein-specific guanine nucleotide-releasing factor 1 [Source:MGI Symbol%3BAcc:MGI:99694]	GO:0090630:activation of GTPase activity;GO:0008283:cell proliferation;GO:0031175:neuron projection development;GO:0048146:positive regulation of fibroblast proliferation;GO:0043547:positive regulation of GTPase activity;GO:0046579:positive regulation of Ras protein signal transduction;GO:0048168:regulation of neuronal synaptic plasticity;GO:2000310:regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:0035020:regulation of Rac protein signal transduction;GO:0046578:regulation of Ras protein signal transduction;GO:0035023:regulation of Rho protein signal transduction;GO:0048167:regulation of synaptic plasticity;GO:0034976:response to endoplasmic reticulum stress;GO:0007264:small GTPase mediated signal transduction;	GO:0097440:apical dendrite;GO:0016327:apicolateral plasma membrane;GO:0016323:basolateral plasma membrane;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0030426:growth cone;GO:0043025:neuronal cell body;	GO:0035254:glutamate receptor binding;GO:0005085:guanyl-nucleotide exchange factor activity;GO:0008022:protein C-terminus binding;GO:0019901:protein kinase binding;GO:0030971:receptor tyrosine kinase binding;GO:0031267:small GTPase binding;	K04349	;ko04010 MAPK signaling pathway;ko04014 Ras signaling pathway;ko04510 Focal adhesion;
ENSMUSG00000086236	2764	17	0.32	15	0.31	44	0.73	71	1.53	37.6818171733721	3.84113462303048	1.94153252793431	0.54089822835554	3.58945995041809	0.000331363732868327	0.00326760866868355	Ups	9	103300777	103338459	+	5830418P13Rik	RIKEN cDNA 5830418P13 gene [Source:MGI Symbol%3BAcc:MGI:3604110]	-	-	-	-	-
ENSMUSG00000022602	3057	29	0.49	20	0.37	77	1.16	63	1.23	47.1108990791243	2.9769234481104	1.57382212300306	0.438658552787937	3.58780676451076	0.00033347128020348	0.00328416737998725	Ups	15	74540932	74544419	-	Arc	activity regulated cytoskeletal-associated protein [Source:MGI Symbol%3BAcc:MGI:88067]	GO:0009952:anterior/posterior pattern specification;GO:0016477:cell migration;GO:0007010:cytoskeleton organization;GO:0006897:endocytosis;GO:0007492:endoderm development;GO:0007612:learning;GO:0007616:long-term memory;GO:0050804:regulation of synaptic transmission;GO:0051028:mRNA transport;GO:2000969:positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0051260:protein homooligomerization;GO:0022604:regulation of cell morphogenesis;GO:0061001:regulation of dendritic spine morphogenesis;GO:1900452:regulation of long term synaptic depression;GO:1900271:regulation of long-term synaptic potentiation;GO:0048168:regulation of neuronal synaptic plasticity;	GO:0001669:acrosomal vesicle;GO:0015629:actin cytoskeleton;GO:0005938:cell cortex;GO:0005737:cytoplasm;GO:0005856:cytoskeleton;GO:0030425:dendrite;GO:0043197:dendritic spine;GO:0031901:early endosome membrane;GO:1903561:extracellular vesicle;GO:0045121:membrane raft;GO:0071598:neuronal ribonucleoprotein granule;GO:0005886:plasma membrane;	GO:0003779:actin binding;GO:0003729:mRNA binding;	K15867	;ko05031 Amphetamine addiction;
ENSMUSG00000026525	1913	124	3.37	119	3.54	49	1.18	52	1.62	84.7205730771187	0.435493254539259	-1.19927772214388	0.334410010028606	-3.58624947273944	0.000335468044526812	0.00329959396714185	Down	1	175489987	175520342	-	Opn3	opsin 3 [Source:MGI Symbol%3BAcc:MGI:1338022]	GO:0071482:cellular response to light stimulus;GO:0071492:cellular response to UV-A;GO:0007186:G-protein coupled receptor signaling pathway;GO:0030216:keratinocyte differentiation;GO:0043066:negative regulation of apoptotic process;GO:0048022:negative regulation of melanin biosynthetic process;GO:0007602:phototransduction;GO:1901857:positive regulation of cellular respiration;GO:0046326:positive regulation of glucose import;GO:0048023:positive regulation of melanin biosynthetic process;GO:0018298:protein-chromophore linkage;GO:0009637:response to blue light;	GO:0005737:cytoplasm;GO:0005887:integral component of plasma membrane;GO:0001750:photoreceptor outer segment;GO:0005886:plasma membrane;	GO:0005502:11-cis retinal binding;GO:0005503:all-trans retinal binding;GO:0008020:G-protein coupled photoreceptor activity;	K04256	-
ENSMUSG00000047632	1772	37	1.08	56	1.80	96	2.49	146	4.91	85.5151556307374	2.76234458577072	1.46589329829769	0.409438428650545	3.58025333168917	0.000343261251561269	0.00336115455392114	Ups	19	36894950	36897015	-	Fgfbp3	fibroblast growth factor binding protein 3 [Source:MGI Symbol%3BAcc:MGI:1919764]	GO:0030534:adult behavior;GO:0007267:cell-cell signaling;GO:0070374:positive regulation of ERK1 and ERK2 cascade;GO:0045743:positive regulation of fibroblast growth factor receptor signaling pathway;GO:0031646:positive regulation of neurological system process;GO:0043117:positive regulation of vascular permeability;	GO:0005576:extracellular region;	GO:0017134:fibroblast growth factor binding;GO:0019838:growth factor binding;GO:0008201:heparin binding;	-	-
ENSMUSG00000018727	2246	46	1.06	60	1.52	16	0.33	11	0.29	32.5712941593218	0.262492059078199	-1.92965431592494	0.539539771301071	-3.57648206594979	0.000348249196120072	0.0033982053258793	Down	11	113588998	113600843	-	Cpsf4l	cleavage and polyadenylation specific factor 4-like [Source:MGI Symbol%3BAcc:MGI:1277182]	GO:0098789:pre-mRNA cleavage required for polyadenylation;	GO:0005847:mRNA cleavage and polyadenylation specificity factor complex;	GO:0046872:metal ion binding;GO:0003723:RNA binding;	K14404	;ko03015 mRNA surveillance pathway;ko05164 Influenza A;
ENSMUSG00000029338	6655	110	0.86	109	0.93	49	0.34	41	0.37	75.8525767300987	0.427122820669142	-1.22727711335156	0.343452839733283	-3.5733497335606	0.000352443531082345	0.00342482199341995	Down	5	98030642	98178902	-	Antxr2	anthrax toxin receptor 2 [Source:MGI Symbol%3BAcc:MGI:1919164]	GO:0022414:reproductive process;GO:1901998:toxin transport;	GO:0009986:cell surface;GO:0009897:external side of plasma membrane;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0046872:metal ion binding;GO:0004888:transmembrane signaling receptor activity;	-	-
ENSMUSG00000025227	2804	185	3.43	237	4.81	125	2.05	76	1.61	152.72236552377	0.487792484438119	-1.03566056460768	0.290072944279713	-3.57034527015041	0.000356510996454893	0.00345777332045498	Down	19	46329560	46363691	+	Mfsd13a	major facilitator superfamily domain containing 13a [Source:MGI Symbol%3BAcc:MGI:1922396]	-	GO:0016021:integral component of membrane;	-	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000099375	2134	96	2.34	105	2.80	27	0.58	42	1.17	66.775512493968	0.363623349523066	-1.45948325190222	0.409264388950048	-3.5661134740955	0.000362314540404556	0.00350740603697188	Down	1	101820683	101822816	-	Gm28187	predicted gene 28187 [Source:MGI Symbol%3BAcc:MGI:5578893]	-	-	-	-	-
ENSMUSG00000041773	4737	79	0.87	48	0.58	157	1.53	119	1.50	99.9070855940435	2.26111713856627	1.17703573373081	0.330772428924924	3.55844571918043	0.000373055865530862	0.00359549883221259	Ups	13	97377613	97389542	+	Enc1	ectodermal-neural cortex 1 [Source:MGI Symbol%3BAcc:MGI:109610]	GO:0017148:negative regulation of translation;GO:0007399:nervous system development;GO:0010976:positive regulation of neuron projection development;GO:0010499:proteasomal ubiquitin-independent protein catabolic process;GO:0016567:protein ubiquitination;	GO:0000785:chromatin;GO:0031463:Cul3-RING ubiquitin ligase complex;GO:0005737:cytoplasm;GO:0005856:cytoskeleton;GO:0043025:neuronal cell body;GO:0016363:nuclear matrix;GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0003779:actin binding;	K10462	-
ENSMUSG00000028439	3724	171	2.38	128	1.96	66	0.82	66	1.06	105.86642325748	0.463183846995664	-1.11034315301443	0.312078356427247	-3.55789861791739	0.00037383353640282	0.00359913336256719	Down	4	41517691	41569538	-	Fam219a	family with sequence similarity 219%2C member A [Source:MGI Symbol%3BAcc:MGI:1919151]	-	-	-	-	-
ENSMUSG00000020798	5508	87	0.82	73	0.75	32	0.27	24	0.26	52.7913861693312	0.363281273807048	-1.46084109434729	0.410787383865721	-3.55619756527092	0.000376261170186867	0.00361729704303788	Down	11	72385745	72441332	-	Spns3	spinster homolog 3 [Source:MGI Symbol%3BAcc:MGI:1924827]	GO:0006869:lipid transport;	GO:0016021:integral component of membrane;	GO:0022857:transmembrane transporter activity;	-	-
ENSMUSG00000102336	6339	237	1.94	276	2.48	65	0.47	131	1.23	176.282851234191	0.410274405867046	-1.28533893744072	0.361526049377921	-3.55531486500739	0.00037752670344994	0.00362313108817881	Down	1	34466083	34472421	-	Gm37233	predicted gene%2C 37233 [Source:MGI Symbol%3BAcc:MGI:5610461]	-	-	-	-	-
ENSMUSG00000107000	3672	82	1.16	110	1.70	18	0.23	38	0.62	61.5366448675182	0.311326600479502	-1.68349924554467	0.473542657048907	-3.55511635643586	0.000377811853977231	0.00362313108817881	Down	5	134295919	134299590	-	Gm43481	predicted gene 43481 [Source:MGI Symbol%3BAcc:MGI:5663618]	-	-	-	-	-
ENSMUSG00000025732	1307	32	1.27	28	1.22	99	3.49	62	2.83	54.5918400748273	2.76109713923629	1.46524164483625	0.412150226690955	3.55511546505819	0.000377813134863565	0.00362313108817881	Ups	17	26082672	26087738	-	Mcrip2	MAPK regulated corepressor interacting protein 2 [Source:MGI Symbol%3BAcc:MGI:1915491]	-	GO:0005737:cytoplasm;GO:0010494:cytoplasmic stress granule;GO:0005634:nucleus;	-	-	-
ENSMUSG00000032109	5750	126	1.14	92	0.91	45	0.36	41	0.42	74.4642345518394	0.412606436497822	-1.27716176801328	0.359315747112129	-3.55442748690533	0.0003788029528909	0.00362808524648911	Down	9	44164014	44179896	-	Nlrx1	NLR family member X1 [Source:MGI Symbol%3BAcc:MGI:2429611]	GO:0045087:innate immune response;GO:0035556:intracellular signal transduction;GO:0043124:negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050728:negative regulation of inflammatory response;GO:0045824:negative regulation of innate immune response;GO:0032688:negative regulation of interferon-beta production;GO:0032715:negative regulation of interleukin-6 production;GO:0039536:negative regulation of RIG-I signaling pathway;	GO:0030054:cell junction;GO:0005741:mitochondrial outer membrane;GO:0005739:mitochondrion;GO:0005886:plasma membrane;	GO:0005524:ATP binding;	K12653	;ko04621 NOD-like receptor signaling pathway;ko04622 RIG-I-like receptor signaling pathway;ko05164 Influenza A;
ENSMUSG00000031196	9905	150	0.79	152	0.87	60	0.28	72	0.43	107.199065179179	0.45983485844132	-1.12081225911787	0.315385629057465	-3.55378354577359	0.000379731608936073	0.00363244197843153	Down	X	74216321	74426221	-	F8	coagulation factor VIII [Source:MGI Symbol%3BAcc:MGI:88383]	GO:0006953:acute-phase response;GO:0007596:blood coagulation;GO:0007597:blood coagulation, intrinsic pathway;	GO:0005615:extracellular space;	GO:0005507:copper ion binding;GO:0016491:oxidoreductase activity;	K03899	;ko04610 Complement and coagulation cascades;
ENSMUSG00000050538	2245	56	1.29	33	0.84	8	0.16	10	0.27	26.0736752786509	0.213635478825522	-2.22677683702295	0.628398649499167	-3.54357355605028	0.000394743178033891	0.00375495774936209	Down	11	97731606	97734925	+	B230217C12Rik	RIKEN cDNA B230217C12 gene [Source:MGI Symbol%3BAcc:MGI:1915377]	-	-	-	-	-
ENSMUSG00000071669	6435	185	1.49	167	1.48	48	0.34	87	0.81	120.626656953273	0.410676447019881	-1.2839258861679	0.362916269871986	-3.53780194704631	0.000403472572108032	0.00381904223500281	Down	16	11140772	11573336	+	Snx29	sorting nexin 29 [Source:MGI Symbol%3BAcc:MGI:1921728]	-	-	GO:0035091:phosphatidylinositol binding;	K17935	-
ENSMUSG00000059159	213	95	23.15	103	27.52	293	63.30	136	38.03	153.406851084355	2.19538649502152	1.13447494676113	0.320862542844164	3.53570390829983	0.00040669024495358	0.0038423833740716	Ups	6	52323715	52323927	-	Gm8129	predicted pseudogene 8129 [Source:MGI Symbol%3BAcc:MGI:3646863]	GO:0034463:90S preribosome assembly;GO:0048318:axial mesoderm development;GO:0002181:cytoplasmic translation;GO:0042474:middle ear morphogenesis;GO:0001503:ossification;GO:0006417:regulation of translation;GO:0022618:ribonucleoprotein complex assembly;GO:0007605:sensory perception of sound;GO:0001501:skeletal system development;	GO:0005829:cytosol;GO:0022625:cytosolic large ribosomal subunit;GO:0022626:cytosolic ribosome;GO:0033291:eukaryotic 80S initiation complex;GO:0042788:polysomal ribosome;GO:0014069:postsynaptic density;GO:0045202:synapse;	GO:0003735:structural constituent of ribosome;	K02923	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000047821	4568	17	0.19	23	0.29	50	0.50	82	1.07	44.1275245452819	3.51677066478028	1.81425125717761	0.515953190965095	3.51630979117318	0.000437590076083864	0.00407903114083281	Ups	11	62711057	62741634	+	Trim16	tripartite motif-containing 16 [Source:MGI Symbol%3BAcc:MGI:2137356]	GO:0043966:histone H3 acetylation;GO:0043967:histone H4 acetylation;GO:0032731:positive regulation of interleukin-1 beta production;GO:0045618:positive regulation of keratinocyte differentiation;GO:0048386:positive regulation of retinoic acid receptor signaling pathway;GO:0045893:positive regulation of transcription, DNA-templated;GO:0060416:response to growth hormone;GO:0046683:response to organophosphorus;GO:0032526:response to retinoic acid;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005886:plasma membrane;GO:0016605:PML body;	GO:0003677:DNA binding;GO:0019966:interleukin-1 binding;GO:0032089:NACHT domain binding;GO:0016740:transferase activity;GO:0008270:zinc ion binding;	K12006	-
ENSMUSG00000044626	4402	40	0.47	54	0.70	142	1.48	84	1.14	78.9900552651254	2.45711980007463	1.29696819988978	0.370170063822013	3.50370904253725	0.00045882637628249	0.00424857708569789	Ups	16	21772567	21814413	-	Liph	lipase%2C member H [Source:MGI Symbol%3BAcc:MGI:2388029]	GO:0006633:fatty acid biosynthetic process;GO:0016042:lipid catabolic process;GO:0019433:triglyceride catabolic process;	GO:0005576:extracellular region;GO:0005615:extracellular space;GO:0005886:plasma membrane;	GO:0008201:heparin binding;GO:0016298:lipase activity;GO:0004465:lipoprotein lipase activity;GO:0004620:phospholipase activity;	K19404	-
ENSMUSG00000036617	16148	26	0.08	20	0.07	79	0.23	54	0.20	44.3509540412279	2.98855499912245	1.57944809328421	0.450967097613832	3.50235771443509	0.000461160020871469	0.00426503483717919	Ups	2	19914591	20815524	+	Etl4	enhancer trap locus 4 [Source:MGI Symbol%3BAcc:MGI:95454]	GO:0048706:embryonic skeletal system development;	GO:0005737:cytoplasm;	GO:0030234:enzyme regulator activity;	-	-
ENSMUSG00000020546	11834	189	0.83	169	0.81	79	0.31	90	0.45	130.030740500627	0.496625441162753	-1.00976992499728	0.288405317028806	-3.50121813078926	0.000463136601074078	0.00427815460293368	Down	11	90367318	90528910	-	Stxbp4	syntaxin binding protein 4 [Source:MGI Symbol%3BAcc:MGI:1342296]	GO:0006974:cellular response to DNA damage stimulus;GO:0071346:cellular response to interferon-gamma;GO:0008286:insulin receptor signaling pathway;GO:1902808:positive regulation of cell cycle G1/S phase transition;GO:0010838:positive regulation of keratinocyte proliferation;GO:0050821:protein stabilization;GO:0006605:protein targeting;GO:0010827:regulation of glucose transport;GO:0061178:regulation of insulin secretion involved in cellular response to glucose stimulus;	GO:0045335:phagocytic vesicle;	GO:0019905:syntaxin binding;	K15302	-
ENSMUSG00000039787	3383	58	0.89	64	1.08	137	1.86	115	2.02	93.2346361915708	2.14533686330004	1.10120419917237	0.314620254848653	3.5001058647737	0.000465073419586731	0.00429345426220399	Ups	2	29759176	29772852	+	Cercam	cerebral endothelial cell adhesion molecule [Source:MGI Symbol%3BAcc:MGI:2139134]	GO:0007155:cell adhesion;	GO:0005788:endoplasmic reticulum lumen;	GO:0042802:identical protein binding;	-	-
ENSMUSG00000112627	2456	169	3.57	178	4.12	105	1.97	57	1.38	124.324241437948	0.477636191258061	-1.06601593883249	0.304898392633628	-3.49629897889766	0.000471759796229849	0.0043421156755033	Down	10	116785662	116799191	+	4933412E12Rik	RIKEN cDNA 4933412E12 gene [Source:MGI Symbol%3BAcc:MGI:1918336]	-	-	-	-	-
ENSMUSG00000097403	3589	63	0.91	41	0.65	130	1.67	101	1.68	83.1574121195885	2.31152876891169	1.20884731823379	0.346098130719916	3.4927877701023	0.000478006246539509	0.00439026077715142	Ups	1	136339654	136343257	-	9230116N13Rik	RIKEN cDNA 9230116N13 gene [Source:MGI Symbol%3BAcc:MGI:2443255]	-	-	-	-	-
ENSMUSG00000032591	2262	45	1.03	62	1.56	14	0.28	14	0.37	33.212299753616	0.272244565808775	-1.87702484285602	0.537566737204368	-3.49170570451875	0.00047994674063153	0.00440161681868653	Down	9	107957635	107962202	+	Mst1	macrophage stimulating 1 (hepatocyte growth factor-like) [Source:MGI Symbol%3BAcc:MGI:96080]	GO:0071456:cellular response to hypoxia;GO:0007566:embryo implantation;GO:0030317:sperm motility;GO:0035978:histone H2A-S139 phosphorylation;GO:0060763:mammary duct terminal end bud growth;GO:0030879:mammary gland development;GO:1904036:negative regulation of epithelial cell apoptotic process;GO:0045721:negative regulation of gluconeogenesis;GO:0010628:positive regulation of gene expression;GO:0033601:positive regulation of mammary gland epithelial cell proliferation;GO:2000479:regulation of cAMP-dependent protein kinase activity;GO:0010758:regulation of macrophage chemotaxis;GO:0046425:regulation of JAK-STAT cascade;GO:0007283:spermatogenesis;	GO:0005737:cytoplasm;GO:0005615:extracellular space;GO:0005773:vacuole;	GO:0019899:enzyme binding;GO:0030971:receptor tyrosine kinase binding;GO:0004252:serine-type endopeptidase activity;	-	-
ENSMUSG00000103432	3496	9	0.13	4	0.07	34	0.45	34	0.58	20.4243925123722	5.50666059892008	2.46117769122997	0.705099892024797	3.4905376090221	0.000482049759761316	0.0044129856813015	Ups	1	160436525	160440020	-	6720464F23Rik	RIKEN cDNA 6720464F23 gene [Source:MGI Symbol%3BAcc:MGI:2444677]	-	-	-	-	-
ENSMUSG00000027313	1637	47	1.49	84	2.92	23	0.65	13	0.47	40.9639124943067	0.280311780974881	-1.83489571549423	0.525798777654798	-3.48972989948426	0.00048350896896988	0.0044237031803008	Down	2	119181710	119184862	+	Chac1	ChaC%2C cation transport regulator 1 [Source:MGI Symbol%3BAcc:MGI:1916315]	GO:0006751:glutathione catabolic process;GO:0070059:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0045746:negative regulation of Notch signaling pathway;GO:0010955:negative regulation of protein processing;GO:0022008:neurogenesis;GO:0007219:Notch signaling pathway;GO:0006986:response to unfolded protein;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005802:trans-Golgi network;	GO:0003839:gamma-glutamylcyclotransferase activity;GO:0005112:Notch binding;	K07232	;ko00480 Glutathione metabolism;ko01100 Metabolic pathways;
ENSMUSG00000038637	6068	63	0.54	105	0.98	33	0.25	22	0.22	54.7888717653971	0.335710622985369	-1.57470990552592	0.451664868997095	-3.48645647163683	0.000489465031322592	0.00446753380375037	Down	7	140774070	140789968	+	Lrrc56	leucine rich repeat containing 56 [Source:MGI Symbol%3BAcc:MGI:1917802]	GO:0030030:cell projection organization;	GO:0005929:cilium;	-	-	-
ENSMUSG00000032611	1236	14	0.59	19	0.87	77	2.87	39	1.88	36.6248025787569	3.5730769281834	1.83716697541603	0.527448829007449	3.48311888164242	0.000495608229676039	0.00451018195480853	Ups	9	108270004	108288133	+	1700102P08Rik	RIKEN cDNA 1700102P08 gene [Source:MGI Symbol%3BAcc:MGI:2148248]	-	-	-	-	-
ENSMUSG00000037366	3616	56	0.80	90	1.42	16	0.20	25	0.41	46.3247396948727	0.295889302538667	-1.75687055602161	0.50463581460845	-3.48146228460771	0.000498684004562548	0.00453129809625915	Down	4	134123631	134154724	+	Pafah2	platelet-activating factor acetylhydrolase 2 [Source:MGI Symbol%3BAcc:MGI:2140321]	GO:0016042:lipid catabolic process;GO:0043066:negative regulation of apoptotic process;	GO:0005737:cytoplasm;GO:0005789:endoplasmic reticulum membrane;	GO:0003847:1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0047179:platelet-activating factor acetyltransferase activity;	K01062	;ko00565 Ether lipid metabolism;ko01100 Metabolic pathways;
ENSMUSG00000109243	2317	69	1.55	68	1.67	15	0.30	25	0.64	43.6703736539724	0.309717311789866	-1.69097606952618	0.485718393938561	-3.48139187362148	0.000498815128895621	0.00453129809625915	Down	7	81523952	81526268	+	Gm45867	predicted gene 45867 [Source:MGI Symbol%3BAcc:MGI:5804982]	-	-	-	-	-
ENSMUSG00000090877	2803	7	0.13	2	0.04	38	0.62	23	0.49	17.302552563205	7.00496268030412	2.80837736456279	0.807000665869888	3.48001864600144	0.000501378886875283	0.00454650730416652	Ups	17	35175412	35178214	-	Hspa1b	heat shock protein 1B [Source:MGI Symbol%3BAcc:MGI:99517]	GO:0046034:ATP metabolic process;GO:0070370:cellular heat acclimation;GO:0034605:cellular response to heat;GO:0034620:cellular response to unfolded protein;	GO:0016235:aggresome;GO:0005814:centriole;GO:0005813:centrosome;GO:0005737:cytoplasm;	GO:0005524:ATP binding;GO:0055131:C3HC4-type RING finger domain binding;GO:0031249:denatured protein binding;	K03283	;ko03040 Spliceosome;ko04010 MAPK signaling pathway;ko04141 Protein processing in endoplasmic reticulum;ko04144 Endocytosis;ko04213 Longevity regulating pathway - multiple species;ko04612 Antigen processing and presentation;ko04915 Estrogen signaling pathway;ko05020 Prion disease;ko05134 Legionellosis;ko05145 Toxoplasmosis;ko05162 Measles;
ENSMUSG00000107325	3291	6	0.09	5	0.09	36	0.50	26	0.47	18.1931355177727	5.83267543156379	2.54415779534121	0.732288420554292	3.47425648682995	0.000512271106102666	0.00461796892473737	Ups	18	44954836	44958126	+	Gm43425	predicted gene 43425 [Source:MGI Symbol%3BAcc:MGI:5663562]	-	-	-	-	-
ENSMUSG00000062309	1423	4	0.15	1	0.04	24	0.78	24	1.00	13.4071477247008	10.1156877412044	3.33852250347318	0.961250518223223	3.47310346281436	0.000514476985668588	0.00463512931741606	Ups	9	57411309	57412731	+	Rpp25	ribonuclease P/MRP 25 subunit [Source:MGI Symbol%3BAcc:MGI:2143151]	GO:0006364:rRNA processing;GO:0001682:tRNA 5'-leader removal;	GO:0034451:centriolar satellite;GO:0030681:multimeric ribonuclease P complex;GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0000172:ribonuclease MRP complex;	GO:0004526:ribonuclease P activity;GO:0033204:ribonuclease P RNA binding;GO:0003723:RNA binding;	K14525	;ko03008 Ribosome biogenesis in eukaryotes;ko03013 RNA transport;
ENSMUSG00000018500	1845	2	0.06	2	0.06	36	0.90	13	0.42	12.8725344916388	12.3321563595395	3.62435318150657	1.04379013550065	3.47230066489194	0.000516018063652655	0.00464628361012907	Ups	11	62139810	62157279	+	Adora2b	adenosine A2b receptor [Source:MGI Symbol%3BAcc:MGI:99403]	GO:0007189:adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0031668:cellular response to extracellular stimulus;GO:0008285:negative regulation of cell proliferation;GO:0032966:negative regulation of collagen biosynthetic process;GO:0043950:positive regulation of cAMP-mediated signaling;GO:0033605:positive regulation of catecholamine secretion;GO:0008284:positive regulation of cell proliferation;GO:0010753:positive regulation of cGMP-mediated signaling;GO:0032722:positive regulation of chemokine production;GO:0002882:positive regulation of chronic inflammatory response to non-antigenic stimulus;GO:0010595:positive regulation of endothelial cell migration;GO:0001938:positive regulation of endothelial cell proliferation;GO:0031284:positive regulation of guanylate cyclase activity;GO:0032755:positive regulation of interleukin-6 production;GO:0043306:positive regulation of mast cell degranulation;GO:0010701:positive regulation of norepinephrine secretion;GO:0010893:positive regulation of steroid biosynthetic process;GO:0010575:positive regulation of vascular endothelial growth factor production;GO:0010906:regulation of glucose metabolic process;GO:2000300:regulation of synaptic vesicle exocytosis;GO:0060087:relaxation of vascular smooth muscle;GO:0042311:vasodilation;	GO:0009986:cell surface;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;GO:0045202:synapse;	GO:0001609:G-protein coupled adenosine receptor activity;GO:0004930:G-protein coupled receptor activity;	K04267	;ko04015 Rap1 signaling pathway;ko04020 Calcium signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04270 Vascular smooth muscle contraction;ko05034 Alcoholism;
ENSMUSG00000061411	9083	55	0.31	73	0.46	130	0.66	142	0.93	100.700565520287	2.226830328493	1.15499163735019	0.332810034863517	3.47042311336509	0.00051963908966852	0.00466519074998658	Ups	2	153249382	153371891	-	Nol4l	nucleolar protein 4-like [Source:MGI Symbol%3BAcc:MGI:1918765]	-	GO:0005829:cytosol;GO:0005654:nucleoplasm;GO:0005730:nucleolus;	-	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000097768	1854	5	0.14	7	0.21	35	0.87	29	0.93	19.0639529414776	5.530513792506	2.46741351508349	0.713024473582615	3.46048923494294	0.00053919479201586	0.0048209987992835	Ups	16	93589021	93591953	-	2310043M15Rik	RIKEN cDNA 2310043M15 gene [Source:MGI Symbol%3BAcc:MGI:1919180]	-	-	-	-	-
ENSMUSG00000053297	4306	11	0.13	8	0.11	61	0.65	26	0.36	25.8664509163679	4.64822960608699	2.21668133453022	0.640846156128774	3.45899138713847	0.000542202242554325	0.00484506362897904	Ups	6	48603698	48610623	+	AI854703	expressed sequence AI854703 [Source:MGI Symbol%3BAcc:MGI:2141510]	GO:0010729:positive regulation of hydrogen peroxide biosynthetic process;GO:1901030:positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005739:mitochondrion;GO:0005634:nucleus;	GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001227:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0046872:metal ion binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K09221	-
ENSMUSG00000031970	2645	54	1.06	34	0.73	13	0.23	6	0.14	25.8841540208793	0.222278808397302	-2.16955768353307	0.627517489652759	-3.45736608032011	0.000545483286554926	0.00486151411489529	Down	8	124231457	124242202	-	Dbndd1	dysbindin (dystrobrevin binding protein 1) domain containing 1 [Source:MGI Symbol%3BAcc:MGI:1919435]	GO:0006469:negative regulation of protein kinase activity;	GO:0005737:cytoplasm;	-	-	-
ENSMUSG00000051727	2568	53	1.07	37	0.82	11	0.20	10	0.23	27.0538476584705	0.243994292874973	-2.03508069192407	0.588865947283778	-3.45593203565454	0.000548393575583122	0.00487482150028498	Down	7	97100530	97108764	+	Kctd14	potassium channel tetramerisation domain containing 14 [Source:MGI Symbol%3BAcc:MGI:1289222]	GO:0051260:protein homooligomerization;	-	-	K13238	;ko00071 Fatty acid degradation;
ENSMUSG00000090628	1366	39	1.48	22	0.92	3	0.10	5	0.22	16.7741339729398	0.139127686315163	-2.84551855110342	0.824104408802928	-3.45286170139139	0.000554673298099377	0.00491923675711732	Down	13	34190949	34192314	-	Gm17083	predicted gene 17083 [Source:MGI Symbol%3BAcc:MGI:4937910]	-	-	-	K03462	;ko00760 Nicotinate and nicotinamide metabolism;ko01100 Metabolic pathways;ko04621 NOD-like receptor signaling pathway;
ENSMUSG00000006241	2183	0	0.00	0	0.00	12	0.25	13	0.35	6.38618083223336	71.4169243978692	6.15819409983508	1.78655939280701	3.44695738895051	0.000566937993380506	0.00502219941680917	Ups	9	21838767	21847168	+	Ccdc159	coiled-coil domain containing 159 [Source:MGI Symbol%3BAcc:MGI:1914369]	-	-	-	-	-
ENSMUSG00000050232	1731	11	0.33	7	0.23	49	1.30	30	1.03	23.9755743352613	4.52177373284042	2.17688880220085	0.631895182271544	3.44501566600863	0.00057102629550035	0.00505257773525814	Ups	X	100775141	100777875	-	Cxcr3	chemokine (C-X-C motif) receptor 3 [Source:MGI Symbol%3BAcc:MGI:1277207]	GO:0007189:adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0001525:angiogenesis;GO:0019722:calcium-mediated signaling;GO:0060326:cell chemotaxis;GO:0007166:cell surface receptor signaling pathway;GO:0007186:G-protein coupled receptor signaling pathway;GO:0006955:immune response;GO:0006954:inflammatory response;GO:0016525:negative regulation of angiogenesis;GO:0001937:negative regulation of endothelial cell proliferation;GO:1900118:negative regulation of execution phase of apoptosis;GO:0045766:positive regulation of angiogenesis;GO:0008284:positive regulation of cell proliferation;GO:0050921:positive regulation of chemotaxis;GO:0007204:positive regulation of cytosolic calcium ion concentration;GO:1900119:positive regulation of execution phase of apoptosis;GO:0051281:positive regulation of release of sequestered calcium ion into cytosol;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0030155:regulation of cell adhesion;GO:0002685:regulation of leukocyte migration;GO:0010818:T cell chemotaxis;	GO:0009986:cell surface;GO:0009897:external side of plasma membrane;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0019957:C-C chemokine binding;GO:0016493:C-C chemokine receptor activity;GO:0019958:C-X-C chemokine binding;GO:0016494:C-X-C chemokine receptor activity;GO:0019956:chemokine binding;GO:0038023:signaling receptor activity;	K04188	;ko04060 Cytokine-cytokine receptor interaction;ko04061 Viral protein interaction with cytokine and cytokine receptor;ko04062 Chemokine signaling pathway;
ENSMUSG00000039713	5430	37	0.35	31	0.32	129	1.09	58	0.64	62.2977718883814	2.79350552085616	1.48207667151941	0.430558590075779	3.44221833144372	0.000576964373265416	0.00510217514397456	Ups	4	152156955	152199857	+	Plekhg5	pleckstrin homology domain containing%2C family G (with RhoGef domain) member 5 [Source:MGI Symbol%3BAcc:MGI:2652860]	GO:0035767:endothelial cell chemotaxis;GO:0043542:endothelial cell migration;GO:0007266:Rho protein signal transduction;	GO:0030424:axon;GO:0005911:cell-cell junction;GO:0005737:cytoplasm;GO:0030139:endocytic vesicle;GO:0030027:lamellipodium;GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;GO:0098793:presynapse;	GO:0005085:guanyl-nucleotide exchange factor activity;	K19464	;ko05200 Pathways in cancer;
ENSMUSG00000103089	2222	32	0.75	42	1.08	2	0.04	9	0.24	21.0013094655778	0.159496114767116	-2.64840681368395	0.770229358902443	-3.43846515725895	0.000585021818666498	0.00516152161532341	Down	1	192941924	192944145	-	Gm38118	predicted gene%2C 38118 [Source:MGI Symbol%3BAcc:MGI:5611346]	-	-	-	-	-
ENSMUSG00000081944	301	49	8.45	56	10.59	15	2.29	14	2.77	32.888077487394	0.287409581493837	-1.79881993656036	0.523492134510758	-3.43619286322514	0.000589950841694017	0.00519604032540842	Down	11	62222247	62222547	+	Gm12276	predicted gene 12276 [Source:MGI Symbol%3BAcc:MGI:3649700]	GO:0006915:apoptotic process;	GO:0005758:mitochondrial intermembrane space;GO:0070469:respiratory chain;	GO:0009055:electron carrier activity;GO:0020037:heme binding;GO:0046872:metal ion binding;	-	-
ENSMUSG00000000394	1494	4	0.14	3	0.11	24	0.74	27	1.08	14.7436344943182	7.6781660842166	2.94076176704657	0.856895907016557	3.43187748122801	0.000599418289492352	0.00526129367548697	Ups	2	62304874	62313994	-	Gcg	glucagon [Source:MGI Symbol%3BAcc:MGI:95674]	GO:0007189:adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007188:adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0042593:glucose homeostasis;GO:0043066:negative regulation of apoptotic process;GO:0032099:negative regulation of appetite;GO:1900118:negative regulation of execution phase of apoptosis;GO:2001243:negative regulation of intrinsic apoptotic signaling pathway;GO:0090280:positive regulation of calcium ion import;GO:0070374:positive regulation of ERK1 and ERK2 cascade;GO:0045722:positive regulation of gluconeogenesis;GO:0051571:positive regulation of histone H3-K4 methylation;GO:0035774:positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0033138:positive regulation of peptidyl-serine phosphorylation;GO:0010800:positive regulation of peptidyl-threonine phosphorylation;GO:0032092:positive regulation of protein binding;GO:0045860:positive regulation of protein kinase activity;GO:0010737:protein kinase A signaling;GO:0050796:regulation of insulin secretion;GO:0014823:response to activity;	GO:0005737:cytoplasm;GO:0005615:extracellular space;GO:0034774:secretory granule lumen;	GO:0031769:glucagon receptor binding;GO:0005179:hormone activity;GO:0042802:identical protein binding;	K05259	;ko04024 cAMP signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04714 Thermogenesis;ko04911 Insulin secretion;ko04922 Glucagon signaling pathway;
ENSMUSG00000073716	780	33	2.20	17	1.24	55	3.24	103	7.86	53.4141641382198	3.41959315662473	1.77382469182622	0.518348440383602	3.42207008573906	0.000621462920303965	0.00542682939632176	Ups	4	146559789	146560568	+	Gm13241	predicted gene 13241 [Source:MGI Symbol%3BAcc:MGI:3649920]	-	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005886:plasma membrane;	-	-	-
ENSMUSG00000034336	3240	8	0.13	2	0.04	36	0.51	26	0.48	17.9161184699564	6.45906533400049	2.69132541328433	0.786618346529303	3.42138652773474	0.000623027172796782	0.00543429958342767	Ups	19	47003137	47013766	+	Ina	internexin neuronal intermediate filament protein%2C alpha [Source:MGI Symbol%3BAcc:MGI:96568]	GO:0030154:cell differentiation;GO:0045104:intermediate filament cytoskeleton organization;GO:0007399:nervous system development;GO:0060052:neurofilament cytoskeleton organization;	GO:0036464:cytoplasmic ribonucleoprotein granule;GO:0043209:myelin sheath;GO:0005883:neurofilament;GO:0098794:postsynapse;	GO:0044877:macromolecular complex binding;	K07608	-
ENSMUSG00000076535	362	64	9.18	60	9.43	184	23.39	93	15.30	98.3121928052699	2.27671781957747	1.18695549238646	0.347454479001575	3.41614675913006	0.000635140070487681	0.00552106156570582	Ups	6	68839249	68840015	-	Igkv1-88	immunoglobulin kappa chain variable 1-88 [Source:MGI Symbol%3BAcc:MGI:4439828]	GO:0002250:adaptive immune response;GO:0006955:immune response;	GO:0005615:extracellular space;GO:0019814:immunoglobulin complex;	GO:0003823:antigen binding;	-	-
ENSMUSG00000019122	3045	35	0.60	18	0.34	71	1.07	77	1.51	50.5555680434549	2.95163358240141	1.56151363546905	0.457118268352731	3.41599481704398	0.000635494565245257	0.00552106156570582	Ups	11	83463745	83469462	-	Ccl9	chemokine (C-C motif) ligand 9 [Source:MGI Symbol%3BAcc:MGI:104533]	GO:0071346:cellular response to interferon-gamma;GO:0071347:cellular response to interleukin-1;GO:0071356:cellular response to tumor necrosis factor;GO:0070098:chemokine-mediated signaling pathway;GO:0007186:G-protein coupled receptor signaling pathway;GO:0006954:inflammatory response;GO:0048247:lymphocyte chemotaxis;GO:0002548:monocyte chemotaxis;GO:0045662:negative regulation of myoblast differentiation;GO:0030593:neutrophil chemotaxis;GO:0070374:positive regulation of ERK1 and ERK2 cascade;GO:0043547:positive regulation of GTPase activity;	GO:0005615:extracellular space;	GO:0048020:CCR chemokine receptor binding;GO:0008009:chemokine activity;	K05510	;ko04060 Cytokine-cytokine receptor interaction;ko04061 Viral protein interaction with cytokine and cytokine receptor;ko04062 Chemokine signaling pathway;
ENSMUSG00000087368	3515	165	2.44	179	2.90	68	0.89	88	1.49	123.779782217751	0.478277795636624	-1.06407928008106	0.311650927232937	-3.41433054452534	0.000639389532183678	0.00555175486212034	Down	X	135642573	135704113	+	BC065397	cDNA sequence BC065397 [Source:MGI Symbol%3BAcc:MGI:3584520]	-	-	-	-	-
ENSMUSG00000040322	3431	116	1.76	99	1.64	49	0.66	42	0.73	75.0510589093998	0.441001673642904	-1.18114396393056	0.345965700227781	-3.41404932093819	0.000640049880567347	0.00555393390774275	Down	3	109030465	109075773	+	Slc25a24	solute carrier family 25 (mitochondrial carrier%2C phosphate carrier)%2C member 24 [Source:MGI Symbol%3BAcc:MGI:1917160]	GO:0015867:ATP transport;GO:0071277:cellular response to calcium ion;GO:0034599:cellular response to oxidative stress;GO:0006839:mitochondrial transport;GO:0010941:regulation of cell death;	GO:0016021:integral component of membrane;GO:0005743:mitochondrial inner membrane;GO:0005739:mitochondrion;	GO:0005347:ATP transmembrane transporter activity;GO:0005509:calcium ion binding;	K14684	-
ENSMUSG00000103621	1934	26	0.70	25	0.74	1	0.02	4	0.12	13.7179839973901	0.104387324046054	-3.25998156158298	0.955263997123239	-3.41264987626494	0.000643345395887483	0.00556780823987292	Down	9	108408031	108409964	+	Gm38366	predicted gene%2C 38366 [Source:MGI Symbol%3BAcc:MGI:5611594]	-	-	-	-	-
ENSMUSG00000028088	5675	94	0.86	101	1.01	39	0.32	39	0.41	67.2258979237273	0.417682490170677	-1.25952142989616	0.369113493592045	-3.41228768864305	0.000644200869081366	0.00557144733586783	Down	3	97536120	97562598	+	Fmo5	flavin containing monooxygenase 5 [Source:MGI Symbol%3BAcc:MGI:1310004]	GO:0017144:drug metabolic process;GO:0070995:NADPH oxidation;GO:0090181:regulation of cholesterol metabolic process;	GO:0005829:cytosol;GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0016021:integral component of membrane;	GO:0004031:aldehyde oxidase activity;GO:0050660:flavin adenine dinucleotide binding;GO:0004497:monooxygenase activity;GO:0004499:N,N-dimethylaniline monooxygenase activity;GO:0050661:NADP binding;	K00485	;ko00982 Drug metabolism - cytochrome P450;
ENSMUSG00000102975	3071	2	0.03	0	0.00	12	0.18	31	0.60	11.8818881596609	23.5433635856781	4.55724854447863	1.33569498725565	3.41189312527261	0.000645134016585517	0.00557496437278058	Ups	1	40127671	40130741	+	Gm37347	predicted gene%2C 37347 [Source:MGI Symbol%3BAcc:MGI:5610575]	-	-	-	-	-
ENSMUSG00000090223	1026	59	2.99	39	2.16	16	0.72	1	0.06	27.6052104778702	0.172659397923324	-2.53399923206372	0.74320264287548	-3.40956703579467	0.000650660849846619	0.00561580983802403	Down	16	96268806	96326993	+	Pcp4	Purkinje cell protein 4 [Source:MGI Symbol%3BAcc:MGI:97509]	GO:0043524:negative regulation of neuron apoptotic process;GO:0006469:negative regulation of protein kinase activity;GO:0033603:positive regulation of dopamine secretion;GO:0045666:positive regulation of neuron differentiation;GO:0010976:positive regulation of neuron projection development;	GO:0030424:axon;GO:0005737:cytoplasm;GO:0005883:neurofilament;GO:0043005:neuron projection;GO:0032991:macromolecular complex;GO:0005829:cytosol;GO:0005634:nucleus;	GO:0005509:calcium ion binding;GO:0005516:calmodulin binding;GO:0003723:RNA binding;	-	-
ENSMUSG00000084854	1551	2	0.07	2	0.07	27	0.80	17	0.65	11.9206707590374	11.3086687906384	3.4993572061622	1.02635172799686	3.40951070739846	0.000650795231653104	0.00561580983802403	Ups	4	44943697	44949133	+	Gm12678	predicted gene 12678 [Source:MGI Symbol%3BAcc:MGI:3650923]	-	-	-	-	-
ENSMUSG00000051397	1735	56	1.68	76	2.49	181	4.80	106	3.64	103.357573828703	2.22021561097456	1.15069978728678	0.337996514265355	3.40447235021892	0.000662920112138188	0.00570758955616338	Ups	6	67511046	67512780	-	Tacstd2	tumor-associated calcium signal transducer 2 [Source:MGI Symbol%3BAcc:MGI:1861606]	GO:0090191:negative regulation of branching involved in ureteric bud morphogenesis;GO:2000146:negative regulation of cell motility;GO:0010633:negative regulation of epithelial cell migration;GO:1900028:negative regulation of ruffle assembly;GO:0051497:negative regulation of stress fiber assembly;GO:1900025:negative regulation of substrate adhesion-dependent cell spreading;GO:2000738:positive regulation of stem cell differentiation;GO:0050678:regulation of epithelial cell proliferation;GO:0060675:ureteric bud morphogenesis;	GO:0009925:basal plasma membrane;GO:0005615:extracellular space;GO:0016021:integral component of membrane;GO:0016328:lateral plasma membrane;GO:0016020:membrane;GO:0005634:nucleus;GO:0005886:plasma membrane;	-	K17288	-
ENSMUSG00000027073	838	7	0.43	5	0.34	44	2.42	22	1.56	19.1510449374654	5.6168712119735	2.48976672405285	0.731466931458408	3.40379942957738	0.000664555313042232	0.00571845744679551	Ups	2	84810805	84813976	+	Prg2	proteoglycan 2%2C bone marrow [Source:MGI Symbol%3BAcc:MGI:103294]	GO:0042742:defense response to bacterium;GO:0002215:defense response to nematode;GO:0032693:negative regulation of interleukin-10 production;GO:0032753:positive regulation of interleukin-4 production;	-	GO:0030246:carbohydrate binding;	K10786	;ko05310 Asthma;
ENSMUSG00000090641	3968	127	1.66	165	2.37	59	0.68	68	1.02	103.672593421684	0.455702792809402	-1.13383488263227	0.333401258153148	-3.40081164934129	0.000671861029249204	0.00576837459266926	Down	13	67186660	67209234	-	Zfp712	zinc finger protein 712 [Source:MGI Symbol%3BAcc:MGI:1925501]	GO:0045892:negative regulation of transcription, DNA-templated;GO:0070895:negative regulation of transposon integration;GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005634:nucleus;	GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0008270:zinc ion binding;	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000020439	4380	59	0.70	70	0.91	18	0.19	22	0.30	41.6630566486611	0.325175847264936	-1.62070799099577	0.476677866077707	-3.4000068103258	0.000673841747920096	0.00578214290017166	Down	11	3467523	3490612	-	Smtn	smoothelin [Source:MGI Symbol%3BAcc:MGI:1354727]	GO:0030036:actin cytoskeleton organization;GO:0003085:negative regulation of systemic arterial blood pressure;GO:0060452:positive regulation of cardiac muscle contraction;	GO:0005737:cytoplasm;GO:0031941:filamentous actin;GO:0005815:microtubule organizing center;	GO:0003779:actin binding;	-	-
ENSMUSG00000026604	13413	58	0.22	95	0.40	187	0.64	136	0.60	118.323450174071	2.17016041186768	1.11780168638065	0.328789737411935	3.39974627912482	0.00067448408057525	0.00578441772457544	Ups	1	189460465	189608892	+	Ptpn14	protein tyrosine phosphatase%2C non-receptor type 14 [Source:MGI Symbol%3BAcc:MGI:102467]	GO:0001946:lymphangiogenesis;GO:0008285:negative regulation of cell proliferation;GO:0046825:regulation of protein export from nucleus;	GO:0005737:cytoplasm;GO:0005856:cytoskeleton;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0004725:protein tyrosine phosphatase activity;GO:0030971:receptor tyrosine kinase binding;GO:0003712:transcription cofactor activity;	K18025	-
ENSMUSG00000114446	816	9	0.57	25	1.74	50	2.82	75	5.47	40.7860443526484	3.88241488987876	1.95695429826468	0.577683296239542	3.38759024365698	0.000705095169827761	0.00601665516646571	Ups	14	70255680	70294816	-	Gm33524	predicted gene%2C 33524 [Source:MGI Symbol%3BAcc:MGI:5592683]	-	-	-	-	-
ENSMUSG00000064984	68	8	6.11	9	7.53	41	27.74	32	28.03	22.4868832370645	4.448232538768	2.15323220932003	0.636452468109874	3.38317834749649	0.000716520851059929	0.00609380517479365	Ups	3	86046098	86046165	-	Snord73a	small nucleolar RNA%2C C/D box U73A [Source:MGI Symbol%3BAcc:MGI:1321388]	-	-	-	-	-
ENSMUSG00000021552	5773	59	0.53	45	0.44	118	0.94	102	1.05	80.7336602247705	2.20742327070992	1.14236329115113	0.33793251753079	3.38044796487228	0.000723677764550603	0.00615126099868013	Ups	13	58381160	58423513	-	Gkap1	G kinase anchoring protein 1 [Source:MGI Symbol%3BAcc:MGI:1891694]	GO:0007199:G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger;GO:0046628:positive regulation of insulin receptor signaling pathway;GO:0007165:signal transduction;	GO:0005794:Golgi apparatus;	GO:0042802:identical protein binding;	-	-
ENSMUSG00000030498	4993	166	1.73	168	1.91	68	0.63	86	1.03	120.712067405199	0.486216035127504	-1.04033062147659	0.308350558945478	-3.37385677209211	0.000741229240251347	0.00628303436706144	Down	7	51511763	51644723	+	Gas2	growth arrest specific 2 [Source:MGI Symbol%3BAcc:MGI:95657]	GO:0051764:actin crosslink formation;GO:0001547:antral ovarian follicle growth;GO:0006915:apoptotic process;GO:0071711:basement membrane organization;GO:0007049:cell cycle;GO:0001544:initiation of primordial ovarian follicle growth;GO:0030728:ovulation;GO:0008360:regulation of cell shape;GO:0008593:regulation of Notch signaling pathway;	GO:0005884:actin filament;GO:0005737:cytoplasm;GO:0016020:membrane;	GO:0051015:actin filament binding;GO:0008093:cytoskeletal adaptor activity;GO:0008017:microtubule binding;	-	-
ENSMUSG00000022432	4047	5	0.06	6	0.08	24	0.27	37	0.54	18.5193309218757	5.90108342484518	2.56097985416198	0.759742558020896	3.37085217502261	0.000749360565786287	0.00633794534791336	Ups	15	84948890	85016165	-	Smc1b	structural maintenance of chromosomes 1B [Source:MGI Symbol%3BAcc:MGI:2154049]	GO:0051321:meiotic cell cycle;GO:0007064:mitotic sister chromatid cohesion;GO:0007062:sister chromatid cohesion;	GO:0000775:chromosome, centromeric region;GO:0008278:cohesin complex;GO:0000794:condensed nuclear chromosome;GO:0005829:cytosol;GO:0000800:lateral element;GO:0030893:meiotic cohesin complex;GO:0034991:nuclear meiotic cohesin complex;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0000795:synaptonemal complex;	GO:0005524:ATP binding;GO:0003677:DNA binding;	K06636	;ko04110 Cell cycle;ko04111 Cell cycle - yeast;ko04113 Meiosis - yeast;ko04114 Oocyte meiosis;
ENSMUSG00000034795	1985	96	2.51	89	2.55	41	0.95	34	1.02	63.7667548771539	0.421555041302945	-1.24620708262737	0.370761415622256	-3.36121028272546	0.000776017204031891	0.0065273058913396	Down	14	77274212	77349697	+	Ccdc122	coiled-coil domain containing 122 [Source:MGI Symbol%3BAcc:MGI:1918358]	-	-	-	-	-
ENSMUSG00000111422	2782	126	2.35	186	3.80	33	0.55	73	1.56	104.098306321365	0.36427570688397	-1.45689730822456	0.433562715235483	-3.36029196475823	0.000778601436771581	0.00654195859257832	Down	10	43621805	43641832	+	1700027J07Rik	RIKEN cDNA 1700027J07 gene [Source:MGI Symbol%3BAcc:MGI:1916693]	-	-	-	-	-
ENSMUSG00000089956	716	0	0.00	5	0.40	28	1.80	22	1.83	13.823053051382	10.2544520054794	3.35817849161967	0.999974934715468	3.35826266742897	0.00078434042677783	0.00657576604932272	Ups	8	3759804	3789044	+	Gm16553	predicted gene 16553 [Source:MGI Symbol%3BAcc:MGI:4414973]	-	-	-	-	-
ENSMUSG00000085957	2026	71	1.82	62	1.74	27	0.61	18	0.53	43.4485916970985	0.349858828143609	-1.51515519860896	0.45128435051575	-3.35742907299436	0.00078670924572272	0.00658482509493024	Down	5	134587000	134589025	-	Syna	syncytin a [Source:MGI Symbol%3BAcc:MGI:2684898]	GO:0060711:labyrinthine layer development;GO:0007520:myoblast fusion;GO:0000768:syncytium formation by plasma membrane fusion;	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	-	-	-
ENSMUSG00000091844	20036	51	0.13	49	0.14	4	0.01	16	0.05	29.6430422410144	0.216429041157255	-2.20803399719004	0.657953929403933	-3.35590973548921	0.000791043825018025	0.00660189541465663	Down	1	44095032	44118906	-	Gm8251	predicted gene 8251 [Source:MGI Symbol%3BAcc:MGI:3647616]	-	-	-	-	-
ENSMUSG00000029718	3823	32	0.43	45	0.67	11	0.13	5	0.08	22.7019052789994	0.211937011790979	-2.23829253896332	0.667762827051935	-3.35192743334489	0.00080251050966035	0.00668236641151665	Down	5	137603365	137612046	-	Pcolce	procollagen C-endopeptidase enhancer protein [Source:MGI Symbol%3BAcc:MGI:105099]	GO:0006508:proteolysis;	GO:0005615:extracellular space;	GO:0005518:collagen binding;GO:0008201:heparin binding;GO:0016504:peptidase activator activity;	K10304	-
ENSMUSG00000099760	2243	58	1.34	82	2.08	10	0.21	26	0.69	43.7000755522492	0.275474360391809	-1.860010047804	0.554955965558169	-3.35163537873357	0.000803357496769932	0.00668403898831803	Down	1	127887253	127895189	+	Gm28800	predicted gene 28800 [Source:MGI Symbol%3BAcc:MGI:5579506]	-	-	-	-	-
ENSMUSG00000109509	397	53	6.93	54	7.74	143	16.57	88	13.20	83.4024575411553	2.21656921425785	1.14832841258552	0.343006039855169	3.34783729484876	0.000814448120089229	0.0067581209207577	Ups	7	30184126	30184522	-	Rps12-ps4	ribosomal protein S12%2C pseudogene 4 [Source:MGI Symbol%3BAcc:MGI:3780139]	GO:0002181:cytoplasmic translation;GO:0090263:positive regulation of canonical Wnt signaling pathway;GO:0006412:translation;	GO:0005829:cytosol;GO:0022626:cytosolic ribosome;GO:0022627:cytosolic small ribosomal subunit;GO:0005794:Golgi apparatus;GO:0043231:intracellular membrane-bounded organelle;GO:0016020:membrane;GO:0005654:nucleoplasm;	GO:0003723:RNA binding;GO:0003735:structural constituent of ribosome;	K02951	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000082727	1264	0	0.00	4	0.18	33	1.20	15	0.71	12.7687600569969	12.0473430395935	3.59064309974404	1.07945332027443	3.32635328670922	0.000879903272510544	0.00720365017654922	Ups	2	11612244	11613507	-	Gm13260	predicted gene 13260 [Source:MGI Symbol%3BAcc:MGI:3650840]	GO:0090261:positive regulation of inclusion body assembly;GO:1901800:positive regulation of proteasomal protein catabolic process;GO:0045899:positive regulation of RNA polymerase II transcriptional preinitiation complex assembly;GO:0030433:ER-associated ubiquitin-dependent protein catabolic process;	GO:0005829:cytosol;GO:0031597:cytosolic proteasome complex;GO:0070062:extracellular exosome;GO:0016234:inclusion body;GO:0016020:membrane;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0022624:proteasome accessory complex;GO:0000502:proteasome complex;GO:0008540:proteasome regulatory particle, base subcomplex;	GO:0005524:ATP binding;GO:0042802:identical protein binding;GO:0036402:proteasome-activating ATPase activity;GO:0030674:protein binding, bridging;	K03064	;ko03050 Proteasome;ko05010 Alzheimer disease;ko05012 Parkinson disease;ko05014 Amyotrophic lateral sclerosis;ko05016 Huntington disease;ko05017 Spinocerebellar ataxia;ko05020 Prion disease;ko05022 Pathways of neurodegeneration - multiple diseases;ko05169 Epstein-Barr virus infection;
ENSMUSG00000019872	2065	74	1.86	96	2.65	39	0.87	25	0.72	57.353311229992	0.386807052223209	-1.3703139967771	0.412010238262649	-3.32592219687403	0.000881265238299694	0.00721050705171042	Down	10	57670431	57687926	+	Smpdl3a	sphingomyelin phosphodiesterase%2C acid-like 3A [Source:MGI Symbol%3BAcc:MGI:1931437]	GO:0009143:nucleoside triphosphate catabolic process;	GO:0005576:extracellular region;GO:0005615:extracellular space;	GO:0008081:phosphoric diester hydrolase activity;GO:0008270:zinc ion binding;	K01128	-
ENSMUSG00000029469	5840	30	0.27	62	0.60	14	0.11	6	0.06	27.4415515418987	0.219988120354829	-2.18450247644617	0.65705666587438	-3.32467896591405	0.000885203999270848	0.00722775193014866	Down	5	122688267	122752581	-	Ift81	intraflagellar transport 81 [Source:MGI Symbol%3BAcc:MGI:1098597]	GO:0030154:cell differentiation;GO:0060271:cilium morphogenesis;GO:0042073:intraciliary transport;GO:0035735:intraciliary transport involved in cilium morphogenesis;GO:0008589:regulation of smoothened signaling pathway;GO:0007283:spermatogenesis;	GO:0005813:centrosome;GO:0036064:ciliary basal body;GO:0005929:cilium;GO:0030992:intraciliary transport particle B;GO:0097225:sperm midpiece;GO:0097228:sperm principal piece;	GO:0015631:tubulin binding;	K19677	-
ENSMUSG00000105977	310	19	3.18	12	2.20	62	9.20	40	7.68	32.8889818812172	3.3983703590394	1.76484308796452	0.531195587658114	3.3223978680719	0.000892473365681659	0.0072677570841012	Ups	3	54964768	54965077	-	Gm43555	predicted gene 43555 [Source:MGI Symbol%3BAcc:MGI:5663692]	GO:0031053:primary miRNA processing;GO:0072091:regulation of stem cell proliferation;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0070877:microprocessor complex;GO:0016604:nuclear body;GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0014069:postsynaptic density;	GO:0003725:double-stranded RNA binding;GO:0020037:heme binding;GO:0042802:identical protein binding;GO:0046872:metal ion binding;GO:0070878:primary miRNA binding;GO:0042803:protein homodimerization activity;	K18419	-
ENSMUSG00000021098	5981	2	0.02	2	0.02	16	0.12	26	0.26	11.9047367827325	11.2126906259122	3.48706060736482	1.04988323391815	3.32137945888624	0.000895736649522887	0.00729045954553288	Ups	12	72927883	72987548	-	4930447C04Rik	RIKEN cDNA 4930447C04 gene [Source:MGI Symbol%3BAcc:MGI:1923051]	GO:0007129:synapsis;GO:0010705:meiotic DNA double-strand break processing involved in reciprocal meiotic recombination;GO:0048477:oogenesis;GO:0051090:regulation of sequence-specific DNA binding transcription factor activity;GO:0007283:spermatogenesis;	GO:0000801:central element;GO:0005694:chromosome;	-	-	-
ENSMUSG00000075420	978	42	2.23	58	3.37	5	0.24	16	0.97	29.9963326643682	0.225302926593548	-2.15006204116943	0.64758548626739	-3.32012079758327	0.000899785052915529	0.0073078940685417	Down	11	115802843	115804746	+	Smim6	small integral membrane protein 6 [Source:MGI Symbol%3BAcc:MGI:1915778]	-	-	-	-	-
ENSMUSG00000052605	1373	77	2.91	111	4.60	46	1.54	24	1.04	63.1341163064496	0.379388821443306	-1.39825092400802	0.421208988254585	-3.31961321576284	0.000901422450600915	0.00731731702356508	Down	7	4847958	4873257	-	Isoc2b	isochorismatase domain containing 2b [Source:MGI Symbol%3BAcc:MGI:1914691]	-	GO:0005737:cytoplasm;GO:0005739:mitochondrion;GO:0005634:nucleus;	-	-	-
ENSMUSG00000104802	1257	47	1.94	37	1.68	127	4.65	71	3.36	69.3226264355259	2.41690120545455	1.27315850193518	0.384110618567303	3.31456210891524	0.000917867864984244	0.0074218605543691	Ups	5	87145018	87146274	+	Gm5869	predicted gene 5869 [Source:MGI Symbol%3BAcc:MGI:3648808]	GO:0071364:cellular response to epidermal growth factor stimulus;GO:1903427:negative regulation of reactive oxygen species biosynthetic process;GO:0010942:positive regulation of cell death;GO:0010976:positive regulation of neuron projection development;GO:1900022:regulation of D-erythro-sphingosine kinase activity;GO:0006412:translation;GO:0006414:translational elongation;	GO:0030864:cortical actin cytoskeleton;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0043209:myelin sheath;GO:0005730:nucleolus;GO:0005634:nucleus;GO:0005886:plasma membrane;GO:0032587:ruffle membrane;	GO:0005516:calmodulin binding;GO:0005525:GTP binding;GO:0003924:GTPase activity;GO:0042802:identical protein binding;GO:0019900:kinase binding;GO:0003729:mRNA binding;GO:0019901:protein kinase binding;GO:0003746:translation elongation factor activity;GO:0000049:tRNA binding;	K03231	;ko03013 RNA transport;ko05134 Legionellosis;ko05140 Leishmaniasis;
ENSMUSG00000025856	3119	113	1.88	93	1.70	49	0.72	39	0.74	72.008690149183	0.444236076526277	-1.17060153560872	0.353540663249229	-3.31108032906387	0.000929365258568613	0.00749257985010048	Down	5	138961769	138983125	-	Pdgfa	platelet derived growth factor%2C alpha [Source:MGI Symbol%3BAcc:MGI:97527]	GO:0030036:actin cytoskeleton organization;GO:0001525:angiogenesis;GO:0009887:organ morphogenesis;GO:0060348:bone development;GO:0030031:cell projection assembly;GO:0048565:digestive tract development;GO:1990401:embryonic lung development;GO:0001942:hair follicle development;GO:0048286:lung alveolus development;GO:0050919:negative chemotaxis;GO:0010512:negative regulation of phosphatidylinositol biosynthetic process;GO:0010544:negative regulation of platelet activation;GO:0048008:platelet-derived growth factor receptor signaling pathway;GO:0051781:positive regulation of cell division;GO:0030335:positive regulation of cell migration;GO:0008284:positive regulation of cell proliferation;GO:0070374:positive regulation of ERK1 and ERK2 cascade;GO:0048146:positive regulation of fibroblast proliferation;GO:0043406:positive regulation of MAP kinase activity;GO:0043410:positive regulation of MAPK cascade;GO:0002053:positive regulation of mesenchymal cell proliferation;GO:0035793:positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway;GO:0014068:positive regulation of phosphatidylinositol 3-kinase signaling;GO:0031954:positive regulation of protein autophosphorylation;GO:0051897:positive regulation of protein kinase B signaling;GO:0060683:regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling;GO:0050730:regulation of peptidyl-tyrosine phosphorylation;GO:0014910:regulation of smooth muscle cell migration;GO:0009611:response to wounding;GO:0043588:skin development;	GO:0009986:cell surface;GO:0005615:extracellular space;GO:0016020:membrane;GO:0005902:microvillus;	GO:0005518:collagen binding;GO:0008083:growth factor activity;GO:0070851:growth factor receptor binding;GO:0042802:identical protein binding;GO:0048407:platelet-derived growth factor binding;GO:0005161:platelet-derived growth factor receptor binding;GO:0046982:protein heterodimerization activity;GO:0042803:protein homodimerization activity;	K04359	;ko01521 EGFR tyrosine kinase inhibitor resistance;ko04010 MAPK signaling pathway;ko04014 Ras signaling pathway;ko04015 Rap1 signaling pathway;ko04020 Calcium signaling pathway;ko04072 Phospholipase D signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04510 Focal adhesion;ko04540 Gap junction;ko04630 JAK-STAT signaling pathway;ko04810 Regulation of actin cytoskeleton;ko05200 Pathways in cancer;ko05202 Transcriptional misregulation in cancer;ko05206 MicroRNAs in cancer;ko05214 Glioma;ko05215 Prostate cancer;ko05218 Melanoma;ko05231 Choline metabolism in cancer;ko05418 Fluid shear stress and atherosclerosis;
ENSMUSG00000045326	6693	28	0.22	53	0.45	11	0.08	6	0.05	24.0342047782024	0.214087626985107	-2.22372667610483	0.673198632265472	-3.30322518425425	0.000955796019098941	0.00765723116998508	Down	3	108760994	108797324	-	Fndc7	fibronectin type III domain containing 7 [Source:MGI Symbol%3BAcc:MGI:2443535]	-	GO:0005576:extracellular region;	-	-	-
ENSMUSG00000022103	3539	5	0.07	4	0.06	35	0.46	20	0.34	15.8032247134455	6.26787045289798	2.64797536186329	0.801859806738829	3.3022921707881	0.00095898123858696	0.00767084940662099	Ups	14	71127560	71217278	+	Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2 [Source:MGI Symbol%3BAcc:MGI:1195462]	GO:0031953:negative regulation of protein autophosphorylation;GO:0007399:nervous system development;GO:0007169:transmembrane receptor protein tyrosine kinase signaling pathway;	GO:0031225:anchored component of membrane;GO:0009897:external side of plasma membrane;GO:0043235:receptor complex;	GO:0016167:glial cell-derived neurotrophic factor receptor activity;GO:0038023:signaling receptor activity;	-	-
ENSMUSG00000028278	5173	12	0.12	15	0.17	50	0.44	41	0.47	29.50808007662	3.49474170785112	1.80518583168869	0.547461307136164	3.29737610340325	0.000975927209765772	0.00777815072528098	Ups	4	32983037	33022180	+	Rragd	Ras-related GTP binding D [Source:MGI Symbol%3BAcc:MGI:1098604]	GO:0071230:cellular response to amino acid stimulus;GO:0071233:cellular response to leucine;GO:1990253:cellular response to leucine starvation;GO:0009267:cellular response to starvation;GO:0032008:positive regulation of TOR signaling;GO:1904263:positive regulation of TORC1 signaling;GO:0010506:regulation of autophagy;GO:0034613:cellular protein localization;	GO:0005813:centrosome;GO:0005737:cytoplasm;GO:1990131:Gtr1-Gtr2 GTPase complex;GO:0043231:intracellular membrane-bounded organelle;GO:0005764:lysosome;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0071986:Ragulator complex;GO:0005829:cytosol;	GO:0019003:GDP binding;GO:0005525:GTP binding;GO:0003924:GTPase activity;GO:0051020:GTPase binding;GO:0046982:protein heterodimerization activity;	K16186	;ko04140 Autophagy - animal;ko04150 mTOR signaling pathway;ko05131 Shigellosis;
ENSMUSG00000043153	8316	59	0.37	40	0.27	14	0.08	13	0.09	30.7444923756048	0.285499229356057	-1.80844124353986	0.548449498757465	-3.29737058313838	0.000975946393337721	0.00777815072528098	Down	12	36431449	36739502	+	Crppa	CDP-L-ribitol pyrophosphorylase A [Source:MGI Symbol%3BAcc:MGI:1923097]	GO:0007411:axon guidance;GO:0008299:isoprenoid biosynthetic process;GO:0006486:protein glycosylation;GO:0035269:protein O-linked mannosylation;	GO:0005829:cytosol;	GO:0070567:cytidylyltransferase activity;GO:0047349:D-ribitol-5-phosphate cytidylyltransferase activity;GO:0042803:protein homodimerization activity;	-	-
ENSMUSG00000036304	5836	76	0.68	53	0.52	114	0.90	164	1.67	103.125471917307	2.30083423677564	1.20215704857889	0.36460820878572	3.29712008564623	0.000976817269217577	0.00778104727593887	Ups	16	43785396	43800154	-	Zdhhc23	zinc finger%2C DHHC domain containing 23 [Source:MGI Symbol%3BAcc:MGI:2685625]	GO:0018230:peptidyl-L-cysteine S-palmitoylation;GO:0072659:protein localization to plasma membrane;GO:0018345:protein palmitoylation;GO:0006612:protein targeting to membrane;	GO:0005783:endoplasmic reticulum;GO:0005794:Golgi apparatus;GO:0000139:Golgi membrane;GO:0016021:integral component of membrane;	GO:0019706:protein-cysteine S-palmitoyltransferase activity;	K18932	-
ENSMUSG00000023979	2441	39	0.83	17	0.40	3	0.06	4	0.10	15.2471364885493	0.132405093886744	-2.91696946833303	0.884908349342861	-3.29635206911449	0.000979491831586505	0.00779425414922028	Down	17	47696318	47703892	+	Guca1b	guanylate cyclase activator 1B [Source:MGI Symbol%3BAcc:MGI:1194489]	GO:0007602:phototransduction;GO:0031282:regulation of guanylate cyclase activity;GO:0007601:visual perception;	GO:0001917:photoreceptor inner segment;GO:0001750:photoreceptor outer segment;GO:0005886:plasma membrane;	GO:0005509:calcium ion binding;GO:0008048:calcium sensitive guanylate cyclase activator activity;GO:0030249:guanylate cyclase regulator activity;	K08328	;ko04744 Phototransduction;
ENSMUSG00000040729	5752	2	0.02	3	0.03	29	0.23	16	0.17	12.3507610951085	9.18585538697927	3.199414071374	0.971977344370282	3.29165498548406	0.000995997191553165	0.0078825605327284	Ups	9	8076462	8134295	-	Cep126	centrosomal protein 126 [Source:MGI Symbol%3BAcc:MGI:2680221]	GO:0060271:cilium morphogenesis;GO:0031122:cytoplasmic microtubule organization;GO:0007052:mitotic spindle organization;	GO:0005813:centrosome;GO:0097546:ciliary base;GO:0005737:cytoplasm;GO:0030496:midbody;	-	-	-
ENSMUSG00000108232	967	130	6.98	132	7.77	78	3.71	33	2.03	90.7416639351451	0.430148174314775	-1.21709438036133	0.369951997631326	-3.28987108639489	0.00100233292775273	0.00792256346090736	Down	6	120928862	120929828	+	Gm43916	predicted gene%2C 43916 [Source:MGI Symbol%3BAcc:MGI:5690308]	-	-	-	-	-
ENSMUSG00000020034	3438	195	2.94	370	6.12	136	1.82	125	2.17	204.479083196821	0.478091228451363	-1.06464215811162	0.323671364393508	-3.2892689166573	0.00100448001629912	0.00793516406763236	Down	10	84412490	84450223	+	Tcp11l2	t-complex 11 (mouse) like 2 [Source:MGI Symbol%3BAcc:MGI:2444679]	GO:0007165:signal transduction;	-	-	-	-
ENSMUSG00000022665	4293	15	0.18	13	0.17	42	0.45	51	0.71	30.6691101005294	3.50851022032536	1.8108585650027	0.550930946622132	3.28690660073724	0.00101294423838121	0.00798585447369533	Ups	16	44913765	44948440	+	Ccdc80	coiled-coil domain containing 80 [Source:MGI Symbol%3BAcc:MGI:1915146]	GO:0030198:extracellular matrix organization;GO:0010811:positive regulation of cell-substrate adhesion;GO:0009617:response to bacterium;	GO:0005604:basement membrane;GO:0031012:extracellular matrix;GO:0005576:extracellular region;GO:0005614:interstitial matrix;	GO:0001968:fibronectin binding;GO:0005539:glycosaminoglycan binding;GO:0008201:heparin binding;	-	-
ENSMUSG00000038260	10826	84	0.40	92	0.48	39	0.17	32	0.18	60.6673517350826	0.418536668270572	-1.25657407112084	0.382714019574562	-3.28332385763576	0.0010259073384529	0.00806317946070569	Down	7	44952056	44983204	-	Trpm4	transient receptor potential cation channel%2C subfamily M%2C member 4 [Source:MGI Symbol%3BAcc:MGI:1915917]	GO:0002250:adaptive immune response;GO:0070588:calcium ion transmembrane transport;GO:0006816:calcium ion transport;GO:0019722:calcium-mediated signaling;GO:0098655:cation transmembrane transport;GO:0071318:cellular response to ATP;GO:0002407:dendritic cell chemotaxis;GO:0098662:inorganic cation transmembrane transport;GO:0086045:membrane depolarization during AV node cell action potential;GO:0086048:membrane depolarization during bundle of His cell action potential;GO:0086047:membrane depolarization during Purkinje myocyte cell action potential;GO:0030502:negative regulation of bone mineralization;GO:0045668:negative regulation of osteoblast differentiation;GO:1904179:positive regulation of adipose tissue development;GO:1903949:positive regulation of atrial cardiac muscle cell action potential;GO:0090263:positive regulation of canonical Wnt signaling pathway;GO:0008284:positive regulation of cell proliferation;GO:0007204:positive regulation of cytosolic calcium ion concentration;GO:0045600:positive regulation of fat cell differentiation;GO:0010460:positive regulation of heart rate;GO:0035774:positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:1904199:positive regulation of regulation of vascular smooth muscle cell membrane depolarization;GO:0045907:positive regulation of vasoconstriction;GO:0051289:protein homotetramerization;GO:0016925:protein sumoylation;GO:0086091:regulation of heart rate by cardiac conduction;GO:0042391:regulation of membrane potential;GO:0002724:regulation of T cell cytokine production;GO:0098911:regulation of ventricular cardiac muscle cell action potential;GO:0098719:sodium ion import across plasma membrane;GO:0042310:vasoconstriction;	GO:0005829:cytosol;GO:0005783:endoplasmic reticulum;GO:0005794:Golgi apparatus;GO:0016021:integral component of membrane;GO:0005887:integral component of plasma membrane;GO:0043025:neuronal cell body;GO:0005654:nucleoplasm;GO:0005886:plasma membrane;GO:0034706:sodium channel complex;GO:0089717:spanning component of membrane;GO:0044214:spanning component of plasma membrane;	GO:0005524:ATP binding;GO:0005227:calcium activated cation channel activity;GO:0005262:calcium channel activity;GO:0005509:calcium ion binding;GO:0005516:calmodulin binding;GO:0005261:cation channel activity;GO:0042802:identical protein binding;GO:0005244:voltage-gated ion channel activity;GO:0005272:sodium channel activity;	K04979	;ko04911 Insulin secretion;
ENSMUSG00000003452	27373	93	0.18	103	0.21	42	0.07	40	0.09	68.4577412990275	0.43606035170499	-1.19740027392199	0.365031804577945	-3.28026286724918	0.00103710407574984	0.00813866627305429	Down	6	149310384	149464827	+	Bicd1	BICD cargo adaptor 1 [Source:MGI Symbol%3BAcc:MGI:1101760]	GO:0009653:anatomical structure morphogenesis;GO:0008298:intracellular mRNA localization;GO:0072393:microtubule anchoring at microtubule organizing center;GO:0072385:minus-end-directed organelle transport along microtubule;GO:1900275:negative regulation of phospholipase C activity;GO:1900737:negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0048260:positive regulation of receptor-mediated endocytosis;GO:0033365:protein localization to organelle;GO:0070507:regulation of microtubule cytoskeleton organization;GO:1900276:regulation of proteinase activated receptor activity;GO:0006396:RNA processing;GO:0034063:stress granule assembly;GO:0016032:viral process;GO:0006310:DNA recombination;	GO:0005813:centrosome;GO:0031410:cytoplasmic vesicle;GO:0005856:cytoskeleton;GO:0005829:cytosol;GO:0005794:Golgi apparatus;GO:0016020:membrane;GO:0048471:perinuclear region of cytoplasm;GO:0005802:trans-Golgi network;	GO:0008093:cytoskeletal adaptor activity;GO:0034452:dynactin binding;GO:0070840:dynein complex binding;GO:0045505:dynein intermediate chain binding;GO:0019901:protein kinase binding;GO:0031871:proteinase activated receptor binding;GO:0031267:small GTPase binding;GO:0005200:structural constituent of cytoskeleton;GO:0004519:endonuclease activity;GO:0046872:metal ion binding;GO:0003964:RNA-directed DNA polymerase activity;	K18739	-
ENSMUSG00000039450	1144	86	3.90	70	3.48	228	9.17	106	5.52	119.736991144419	2.17733522679058	1.12256354477744	0.342464320608052	3.27789926490533	0.00104582710657856	0.00820292217507704	Ups	11	120616225	120618107	-	Dcxr	dicarbonyl L-xylulose reductase [Source:MGI Symbol%3BAcc:MGI:1915130]	GO:0042732:D-xylose metabolic process;GO:0006006:glucose metabolic process;GO:0006739:NADP metabolic process;GO:2000379:positive regulation of reactive oxygen species metabolic process;GO:0005997:xylulose metabolic process;	GO:0016324:apical plasma membrane;GO:0005903:brush border;GO:0005881:cytoplasmic microtubule;GO:0005902:microvillus;	GO:0004090:carbonyl reductase (NADPH) activity;GO:0042802:identical protein binding;GO:0044105:L-xylulose reductase (NAD+) activity;GO:0050038:L-xylulose reductase (NADP+) activity;GO:0016614:oxidoreductase activity, acting on CH-OH group of donors;GO:0016655:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;	K03331	;ko00040 Pentose and glucuronate interconversions;ko01100 Metabolic pathways;
ENSMUSG00000054206	1472	5	0.18	14	0.54	56	1.75	29	1.17	25.6370428810143	4.52588597020248	2.17820023632911	0.664860381935601	3.27617691700585	0.00105222625052554	0.00824046850130679	Ups	10	79524854	79531095	+	Gzmm	granzyme M (lymphocyte met-ase 1) [Source:MGI Symbol%3BAcc:MGI:99549]	GO:0006915:apoptotic process;GO:0008219:cell death;GO:0019835:cytolysis;GO:0045087:innate immune response;GO:0001913:T cell mediated cytotoxicity;	GO:0005576:extracellular region;	GO:0004175:endopeptidase activity;GO:0004252:serine-type endopeptidase activity;GO:0008236:serine-type peptidase activity;	K08649	-
ENSMUSG00000110866	3205	6	0.10	0	0.00	31	0.45	21	0.39	14.4006361542349	9.0436967120031	3.17691261090569	0.96978524817105	3.27589290195652	0.00105328494184741	0.00824454890162747	Ups	9	25766611	25770948	-	Gm48362	predicted gene%2C 48362 [Source:MGI Symbol%3BAcc:MGI:6097831]	-	-	-	-	-
ENSMUSG00000106767	2823	95	1.75	83	1.67	26	0.42	39	0.82	59.98180917297	0.387345248042398	-1.36830805411131	0.418066175091767	-3.27294609235239	0.0010643277461025	0.0083140100146387	Down	5	65774292	65777114	+	Gm42727	predicted gene 42727 [Source:MGI Symbol%3BAcc:MGI:5662864]	-	-	-	-	-
ENSMUSG00000020131	2958	38	0.67	18	0.35	110	1.71	53	1.07	53.5271455474098	2.97964058191324	1.57513831660559	0.48172655483093	3.26977680762982	0.00107632371947641	0.008386355647587	Ups	10	80157117	80165332	-	Pcsk4	proprotein convertase subtilisin/kexin type 4 [Source:MGI Symbol%3BAcc:MGI:97514]	GO:0007340:acrosome reaction;GO:0007339:binding of sperm to zona pellucida;GO:0009566:fertilization;GO:0016486:peptide hormone processing;GO:0016485:protein processing;GO:0022414:reproductive process;GO:0048240:sperm capacitation;	GO:0002080:acrosomal membrane;GO:0001669:acrosomal vesicle;GO:0005788:endoplasmic reticulum lumen;GO:0030173:integral component of Golgi membrane;GO:0016020:membrane;GO:0005802:trans-Golgi network;	GO:0004252:serine-type endopeptidase activity;	K08671	-
ENSMUSG00000118506	3097	49	0.82	68	1.25	23	0.34	13	0.25	37.4423897629362	0.314936991543618	-1.66686487287858	0.510464703503151	-3.2653871294909	0.00109314562004651	0.00848096132039661	Down	3	89970103	89975654	+	1700094D03Rik	RIKEN cDNA 1700094D03 gene [Source:MGI Symbol%3BAcc:MGI:1920795]	-	-	-	-	-
ENSMUSG00000004633	5812	51	0.46	37	0.36	15	0.12	7	0.07	26.6640478940385	0.256884724504848	-1.9608069910882	0.60063951590445	-3.2645321181301	0.00109645031121553	0.00849568927346079	Down	6	54016539	54278795	+	Chn2	chimerin 2 [Source:MGI Symbol%3BAcc:MGI:1917243]	GO:0035556:intracellular signal transduction;GO:0043547:positive regulation of GTPase activity;GO:0043087:regulation of GTPase activity;GO:0051056:regulation of small GTPase mediated signal transduction;GO:0001675:acrosome assembly;	GO:0005829:cytosol;GO:0016020:membrane;GO:0045202:synapse;	GO:0005096:GTPase activator activity;GO:0046872:metal ion binding;GO:0001565:phorbol ester receptor activity;	-	-
ENSMUSG00000019944	6075	137	1.17	101	0.95	51	0.39	53	0.52	84.0330626485674	0.459084882818528	-1.12316716848252	0.34454800058948	-3.25982785144862	0.00111479855001792	0.00860741236957445	Down	10	68987264	69127621	+	Rhobtb1	Rho-related BTB domain containing 1 [Source:MGI Symbol%3BAcc:MGI:1916538]	GO:0007015:actin filament organization;GO:0030865:cortical cytoskeleton organization;GO:0043652:engulfment of apoptotic cell;GO:0007163:establishment or maintenance of cell polarity;GO:0032956:regulation of actin cytoskeleton organization;GO:0008360:regulation of cell shape;GO:0007264:small GTPase mediated signal transduction;	GO:0005938:cell cortex;GO:0042995:cell projection;GO:0031410:cytoplasmic vesicle;GO:0005856:cytoskeleton;GO:0043231:intracellular membrane-bounded organelle;GO:0005886:plasma membrane;	GO:0005525:GTP binding;GO:0003924:GTPase activity;GO:0019901:protein kinase binding;	K07868	;ko04120 Ubiquitin mediated proteolysis;
ENSMUSG00000086350	5383	24	0.23	39	0.41	71	0.61	93	1.03	57.6680308560516	2.74375100161329	1.45614956130759	0.44707056272679	3.25709112321371	0.00112560292285462	0.0086646562344642	Ups	1	178105162	178146114	-	B230369F24Rik	RIKEN cDNA B230369F24 gene [Source:MGI Symbol%3BAcc:MGI:2443392]	-	-	-	-	-
ENSMUSG00000046856	2496	0	0.00	0	0.00	5	0.09	18	0.43	6.17305144147674	68.6816363124219	6.10185250626723	1.87407248382449	3.25593196577698	0.00113020829803095	0.00868832760574753	Ups	1	63221850	63253702	-	Gpr1	G protein-coupled receptor 1 [Source:MGI Symbol%3BAcc:MGI:2385324]	GO:0042593:glucose homeostasis;GO:0007218:neuropeptide signaling pathway;	GO:0005887:integral component of plasma membrane;GO:0043231:intracellular membrane-bounded organelle;GO:0043005:neuron projection;GO:0005654:nucleoplasm;GO:0005886:plasma membrane;	GO:0097004:adipokinetic hormone binding;GO:0097003:adipokinetic hormone receptor activity;GO:0004930:G-protein coupled receptor activity;GO:0042923:neuropeptide binding;GO:0042277:peptide binding;	K04310	-
ENSMUSG00000112784	530	8	0.78	12	1.29	46	3.99	32	3.60	24.3846744649377	4.01258532135863	2.00453206921744	0.615671762364134	3.25584538995289	0.00113055296512178	0.00868832760574753	Ups	12	76334668	76353757	-	Gm34868	predicted gene%2C 34868 [Source:MGI Symbol%3BAcc:MGI:5594027]	-	-	-	-	-
ENSMUSG00000120574	1128	27	1.24	17	0.86	0	0.00	3	0.16	11.4483001192707	0.0736037398965731	-3.76407711652015	1.15661654047151	-3.25438638028268	0.00113637606626417	0.00872131661666405	Down	12	118265359	118327310	+	-	novel transcript	-	-	-	-	-
ENSMUSG00000038319	4845	0	0.00	1	0.01	25	0.24	15	0.18	10.1815333408918	40.9563031815793	5.35601359483715	1.64615529761006	3.25365024953185	0.00113932457349995	0.00873957129066946	Ups	5	24524587	24556602	-	Kcnh2	potassium voltage-gated channel%2C subfamily H (eag-related)%2C member 2 [Source:MGI Symbol%3BAcc:MGI:1341722]	GO:0060048:cardiac muscle contraction;GO:0035690:cellular response to drug;GO:0086010:membrane depolarization during action potential;GO:0086009:membrane repolarization;GO:0086011:membrane repolarization during action potential;GO:0086013:membrane repolarization during cardiac muscle cell action potential;GO:0098915:membrane repolarization during ventricular cardiac muscle cell action potential;GO:1903765:negative regulation of potassium ion export across plasma membrane;GO:1901380:negative regulation of potassium ion transmembrane transport;GO:1901381:positive regulation of potassium ion transmembrane transport;GO:0045893:positive regulation of transcription, DNA-templated;GO:0097623:potassium ion export across plasma membrane;GO:0055075:potassium ion homeostasis;GO:1990573:potassium ion import across plasma membrane;GO:0071805:potassium ion transmembrane transport;GO:0006813:potassium ion transport;GO:0086091:regulation of heart rate by cardiac conduction;GO:0042391:regulation of membrane potential;GO:0060306:regulation of membrane repolarization;GO:1901379:regulation of potassium ion transmembrane transport;GO:0060307:regulation of ventricular cardiac muscle cell membrane repolarization;GO:0086005:ventricular cardiac muscle cell action potential;GO:0007420:brain development;GO:0021510:spinal cord development;	GO:0009986:cell surface;GO:0005887:integral component of plasma membrane;GO:1902937:inward rectifier potassium channel complex;GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;GO:0008076:voltage-gated potassium channel complex;	GO:0055131:C3HC4-type RING finger domain binding;GO:0005251:delayed rectifier potassium channel activity;GO:0042802:identical protein binding;GO:0005242:inward rectifier potassium channel activity;GO:0005216:ion channel activity;GO:0005267:potassium channel activity;GO:0042803:protein homodimerization activity;GO:0044877:macromolecular complex binding;GO:0097110:scaffold protein binding;GO:0000976:transcription regulatory region sequence-specific DNA binding;GO:0031625:ubiquitin protein ligase binding;GO:0005249:voltage-gated potassium channel activity;GO:1902282:voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;	K04905	-
ENSMUSG00000107352	6548	86	0.68	76	0.66	25	0.18	34	0.31	54.4866847580105	0.384869097276275	-1.37756025901038	0.42370592177403	-3.25121785705195	0.00114911767280131	0.00880148371365401	Down	5	31718156	31726416	-	Gm43660	predicted gene 43660 [Source:MGI Symbol%3BAcc:MGI:5663797]	-	-	-	-	-
ENSMUSG00000118607	2798	35	0.65	38	0.77	11	0.18	5	0.11	21.6624363065914	0.224267379226995	-2.15670830616163	0.664212600045231	-3.24701504610838	0.00116622224274005	0.0089146818894197	Down	1	85454323	85479899	+	Gm7592	predicted gene 7592 [Source:MGI Symbol%3BAcc:MGI:3644077]	GO:0006357:regulation of transcription from RNA polymerase II promoter;	GO:0005634:nucleus;	GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;	K15413	;ko05168 Herpes simplex virus 1 infection;ko05203 Viral carcinogenesis;
ENSMUSG00000046329	5294	120	1.18	130	1.40	74	0.64	35	0.39	87.5229080979836	0.444065333280757	-1.17115614564061	0.361479917906141	-3.23989269562881	0.0011957468876868	0.00911311271162493	Down	17	57350711	57366863	-	Slc25a23	solute carrier family 25 (mitochondrial carrier%3B phosphate carrier)%2C member 23 [Source:MGI Symbol%3BAcc:MGI:1914222]	GO:0036444:calcium ion transmembrane import into mitochondrion;GO:0071277:cellular response to calcium ion;GO:0006851:mitochondrial calcium ion transport;GO:0051561:positive regulation of mitochondrial calcium ion concentration;GO:1900069:regulation of cellular hyperosmotic salinity response;GO:0002082:regulation of oxidative phosphorylation;GO:0051282:regulation of sequestering of calcium ion;GO:0097274:urea homeostasis;GO:0051503:adenine nucleotide transport;GO:0043457:regulation of cellular respiration;	GO:0016021:integral component of membrane;GO:0005743:mitochondrial inner membrane;GO:0005739:mitochondrion;	GO:0005347:ATP transmembrane transporter activity;GO:0005509:calcium ion binding;	K14684	-
ENSMUSG00000111342	1540	97	3.27	41	1.52	16	0.48	22	0.85	42.9282751689848	0.293806669213392	-1.7670609504163	0.546045937962088	-3.23610309603473	0.00121173610825216	0.00921207807830374	Down	10	43700196	43709388	+	4933404K13Rik	RIKEN cDNA 4933404K13 gene [Source:MGI Symbol%3BAcc:MGI:1918268]	-	-	-	-	-
ENSMUSG00000029135	9680	17	0.09	14	0.08	48	0.23	48	0.30	31.9319414211998	3.24711827826015	1.69915993662631	0.5252741640345	3.23480584610423	0.00121725473117543	0.00924028913259602	Ups	5	32293145	32315186	+	Fosl2	fos-like antigen 2 [Source:MGI Symbol%3BAcc:MGI:102858]	GO:0003334:keratinocyte development;GO:0048146:positive regulation of fibroblast proliferation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-templated;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0032355:response to estradiol;GO:0001666:response to hypoxia;GO:0006366:transcription from RNA polymerase II promoter;	GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0003682:chromatin binding;GO:0003677:DNA binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003690:double-stranded DNA binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000977:RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565:sequence-specific DNA binding;GO:0000976:transcription regulatory region sequence-specific DNA binding;	K09030	;ko04380 Osteoclast differentiation;
ENSMUSG00000026988	3598	154	2.22	144	2.28	93	1.19	48	0.79	107.031010340985	0.484015720605661	-1.04687418856207	0.324219111968165	-3.22890955504458	0.00124263187777913	0.00937830059318544	Down	2	59682708	59712935	-	Wdsub1	WD repeat%2C SAM and U-box domain containing 1 [Source:MGI Symbol%3BAcc:MGI:1919387]	-	-	GO:0004842:ubiquitin-protein transferase activity;	-	-
ENSMUSG00000084917	2581	55	1.11	77	1.70	8	0.14	25	0.58	41.0058818595316	0.269190268383144	-1.89330183950508	0.586839225269045	-3.22627008894484	0.00125414946616972	0.00945018570724646	Down	9	80026177	80029219	-	Gm17477	predicted gene%2C 17477 [Source:MGI Symbol%3BAcc:MGI:4937111]	-	-	-	-	-
ENSMUSG00000029510	4274	16	0.19	17	0.23	45	0.48	56	0.78	33.9882659614745	3.23068063220501	1.69183814054232	0.525311588738412	3.22063738324419	0.00127905871713253	0.00960484151249278	Ups	5	138271917	138278267	-	Gpc2	glypican 2 (cerebroglycan) [Source:MGI Symbol%3BAcc:MGI:1919201]	GO:0016477:cell migration;GO:0030182:neuron differentiation;GO:0010976:positive regulation of neuron projection development;GO:0009966:regulation of signal transduction;GO:0007224:smoothened signaling pathway;	GO:0046658:anchored component of plasma membrane;GO:0009986:cell surface;GO:0005783:endoplasmic reticulum;GO:0005615:extracellular space;GO:0005796:Golgi lumen;GO:0045202:synapse;	-	K08108	-
ENSMUSG00000120263	496	20	2.09	19	2.18	0	0.00	2	0.24	10.0173415412804	0.0546497253596547	-4.19364194407443	1.30573569386289	-3.2117081303552	0.00131948354288018	0.00981905496348036	Down	17	84496038	84496533	+	-	novel transcript	-	-	-	-	-
ENSMUSG00000017314	4807	17	0.18	24	0.28	81	0.78	42	0.52	40.3368412963428	3.05065757596295	1.60912025229133	0.501026069951875	3.21164974997387	0.00131975168121384	0.00981905496348036	Ups	11	101947841	101979341	-	Mpp2	membrane protein%2C palmitoylated 2 (MAGUK p55 subfamily member 2) [Source:MGI Symbol%3BAcc:MGI:1858257]	GO:0060079:regulation of excitatory postsynaptic membrane potential;GO:0060291:long-term synaptic potentiation;GO:0051260:protein homooligomerization;	GO:0005737:cytoplasm;GO:0005856:cytoskeleton;GO:0032590:dendrite membrane;GO:0043198:dendritic shaft;GO:0043197:dendritic spine;GO:0014069:postsynaptic density;	GO:0030165:PDZ domain binding;GO:0044325:ion channel binding;	-	-
ENSMUSG00000086537	3149	32	0.53	8	0.14	76	1.11	57	1.08	42.9190673777975	3.48159134824464	1.79974687660781	0.560918924581808	3.20856865000518	0.00133397458680528	0.00989127964897107	Ups	2	174123024	174137229	-	Gnasas1	GNAS antisense RNA 1 [Source:MGI Symbol%3BAcc:MGI:1861674]	-	-	-	-	-
ENSMUSG00000057895	2130	13	0.32	13	0.35	56	1.21	33	0.92	28.3907683848505	3.51025201072716	1.81157460932613	0.565372497076494	3.20421424581788	0.00135431655172614	0.0100082361465873	Ups	9	122752137	122760093	+	Zfp105	zinc finger protein 105 [Source:MGI Symbol%3BAcc:MGI:1277119]	GO:0071300:cellular response to retinoic acid;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0006355:regulation of transcription, DNA-templated;GO:0007283:spermatogenesis;	GO:0005634:nucleus;GO:0048471:perinuclear region of cytoplasm;	GO:0003677:DNA binding;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046872:metal ion binding;GO:0000977:RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565:sequence-specific DNA binding;	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000025656	8776	44	0.26	32	0.21	7	0.04	10	0.07	22.7639958909437	0.23649775294197	-2.08010161886974	0.649518059288177	-3.20253084440696	0.00136225711000079	0.0100554699840577	Down	X	94092541	94240462	-	Arhgef9	CDC42 guanine nucleotide exchange factor (GEF) 9 [Source:MGI Symbol%3BAcc:MGI:2442233]	GO:0043113:receptor clustering;GO:0007264:small GTPase mediated signal transduction;GO:0051056:regulation of small GTPase mediated signal transduction;	GO:0005938:cell cortex;GO:0005829:cytosol;GO:0005886:plasma membrane;GO:0014069:postsynaptic density;GO:0005737:cytoplasm;	GO:0005085:guanyl-nucleotide exchange factor activity;	K05769	;ko04810 Regulation of actin cytoskeleton;
ENSMUSG00000034394	4350	2	0.02	0	0.00	26	0.28	12	0.16	9.79615079396229	19.4293572998745	4.28016627395682	1.33664275051235	3.2021767015279	0.00136393305016012	0.010059908317054	Ups	11	4207557	4222514	+	Lif	leukemia inhibitory factor [Source:MGI Symbol%3BAcc:MGI:96787]	GO:0031100:organ regeneration;GO:0048708:astrocyte differentiation;GO:0001974:blood vessel remodeling;GO:0046697:decidualization;GO:0007566:embryo implantation;GO:0006955:immune response;GO:0048861:leukemia inhibitory factor signaling pathway;GO:0048286:lung alveolus development;GO:0030324:lung development;GO:0060463:lung lobe morphogenesis;GO:0060426:lung vasculature development;GO:0060135:maternal process involved in female pregnancy;GO:0048644:muscle organ morphogenesis;GO:0016525:negative regulation of angiogenesis;GO:0008285:negative regulation of cell proliferation;GO:0070373:negative regulation of ERK1 and ERK2 cascade;GO:0046888:negative regulation of hormone secretion;GO:0045835:negative regulation of meiotic nuclear division;GO:0048666:neuron development;GO:0048711:positive regulation of astrocyte differentiation;GO:0033630:positive regulation of cell adhesion mediated by integrin;GO:0008284:positive regulation of cell proliferation;GO:0051461:positive regulation of corticotropin secretion;GO:0010628:positive regulation of gene expression;GO:1901676:positive regulation of histone H3-K27 acetylation;GO:0045651:positive regulation of macrophage differentiation;GO:0043410:positive regulation of MAPK cascade;GO:0072108:positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0010976:positive regulation of neuron projection development;GO:0033138:positive regulation of peptidyl-serine phosphorylation;GO:0033141:positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0050731:positive regulation of peptidyl-tyrosine phosphorylation;GO:1900182:positive regulation of protein localization to nucleus;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0042531:positive regulation of tyrosine phosphorylation of STAT protein;GO:0045595:regulation of cell differentiation;GO:0072307:regulation of metanephric nephron tubule epithelial cell differentiation;GO:1903025:regulation of RNA polymerase II regulatory region sequence-specific DNA binding;GO:0060041:retina development in camera-type eye;GO:0060708:spongiotrophoblast differentiation;GO:0048863:stem cell differentiation;GO:0019827:stem cell maintenance;GO:0060290:transdifferentiation;GO:0060707:trophoblast giant cell differentiation;GO:0007260:tyrosine phosphorylation of STAT protein;	GO:0005829:cytosol;GO:0005615:extracellular space;	GO:0005125:cytokine activity;GO:0008083:growth factor activity;GO:0005146:leukemia inhibitory factor receptor binding;GO:0005102:receptor binding;	K05419	;ko04060 Cytokine-cytokine receptor interaction;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04630 JAK-STAT signaling pathway;ko04668 TNF signaling pathway;
ENSMUSG00000030747	3083	34	0.57	52	0.96	125	1.87	76	1.47	70.9360688813982	2.38816134930756	1.25590031146964	0.392628219424562	3.19870108498644	0.00138048221949069	0.0101429393165646	Ups	7	98802865	98831926	-	Dgat2	diacylglycerol O-acyltransferase 2 [Source:MGI Symbol%3BAcc:MGI:1915050]	GO:0038183:bile acid signaling pathway;GO:0071400:cellular response to oleic acid;GO:0035356:cellular triglyceride homeostasis;GO:0042632:cholesterol homeostasis;GO:0006651:diacylglycerol biosynthetic process;GO:0046339:diacylglycerol metabolic process;GO:0060613:fat pad development;GO:0055089:fatty acid homeostasis;GO:0006071:glycerol metabolic process;GO:0006629:lipid metabolic process;GO:0019915:lipid storage;GO:0035336:long-chain fatty-acyl-CoA metabolic process;GO:0034383:low-density lipoprotein particle clearance;GO:0006640:monoacylglycerol biosynthetic process;GO:0046322:negative regulation of fatty acid oxidation;GO:0045722:positive regulation of gluconeogenesis;GO:0010867:positive regulation of triglyceride biosynthetic process;GO:0090181:regulation of cholesterol metabolic process;GO:0050746:regulation of lipoprotein metabolic process;GO:0097006:regulation of plasma lipoprotein particle levels;GO:0019432:triglyceride biosynthetic process;	GO:0005829:cytosol;GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0030176:integral component of endoplasmic reticulum membrane;GO:0016021:integral component of membrane;GO:0043231:intracellular membrane-bounded organelle;GO:0005811:lipid particle;GO:0016020:membrane;GO:1990578:perinuclear endoplasmic reticulum membrane;GO:0048471:perinuclear region of cytoplasm;GO:0005739:mitochondrion;	GO:0003846:2-acylglycerol O-acyltransferase activity;GO:0004144:diacylglycerol O-acyltransferase activity;GO:0008374:O-acyltransferase activity;GO:0042803:protein homodimerization activity;GO:0050252:retinol O-fatty-acyltransferase activity;	K11160	;ko00561 Glycerolipid metabolism;ko01100 Metabolic pathways;ko04975 Fat digestion and absorption;
ENSMUSG00000010721	5850	65	0.58	54	0.53	24	0.19	16	0.16	38.7891708616208	0.347781389981515	-1.52374735976934	0.476547210501156	-3.19747409321084	0.00138636863861506	0.0101795953033307	Down	5	29434800	29583388	-	Lmbr1	limb region 1 [Source:MGI Symbol%3BAcc:MGI:1861746]	GO:0042733:embryonic digit morphogenesis;GO:0035116:embryonic hindlimb morphogenesis;GO:0007165:signal transduction;	GO:0005887:integral component of plasma membrane;	GO:0004888:transmembrane signaling receptor activity;	-	-
ENSMUSG00000071451	555	92	8.61	74	7.59	208	17.25	116	12.45	120.345315926548	2.00031160119136	1.00022475523871	0.312825913260606	3.19738459264228	0.00138679891669869	0.0101795953033307	Ups	13	34346947	34362156	+	Psmg4	proteasome (prosome%2C macropain) assembly chaperone 4 [Source:MGI Symbol%3BAcc:MGI:1916916]	GO:0043248:proteasome assembly;	GO:0032991:macromolecular complex;	GO:0044877:macromolecular complex binding;	K11878	-
ENSMUSG00000067377	2060	40	1.01	47	1.30	150	3.35	65	1.88	73.7784054010493	2.49750802602535	1.32048931428931	0.41302103153419	3.19714787739568	0.00138793752975872	0.0101830785078087	Ups	X	132791817	132799178	-	Tspan6	tetraspanin 6 [Source:MGI Symbol%3BAcc:MGI:1926264]	GO:1901223:negative regulation of NIK/NF-kappaB signaling;GO:0039532:negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway;	GO:0005887:integral component of plasma membrane;	-	K17295	-
ENSMUSG00000075225	10197	46	0.23	19	0.11	7	0.03	4	0.02	18.3165411422521	0.176025056136656	-2.50614729221103	0.784444664050913	-3.19480443562348	0.00139925621509691	0.0102465113669036	Down	10	41414842	41592630	-	Ccdc162	coiled-coil domain containing 162 [Source:MGI Symbol%3BAcc:MGI:1923223]	-	-	-	-	-
ENSMUSG00000020732	5330	109	1.06	106	1.13	58	0.50	39	0.44	76.378072231425	0.465741234241482	-1.10239947856071	0.345199788077249	-3.19351145810672	0.00140553759561362	0.0102864191110327	Down	11	114982257	115053062	+	Rab37	RAB37%2C member RAS oncogene family [Source:MGI Symbol%3BAcc:MGI:1929945]	GO:0015031:protein transport;	GO:0005793:endoplasmic reticulum-Golgi intermediate compartment;GO:0005768:endosome;GO:0005794:Golgi apparatus;GO:0030141:secretory granule;	GO:0005525:GTP binding;GO:0003924:GTPase activity;	K07914	-
ENSMUSG00000117179	915	24	1.36	15	0.93	1	0.05	0	0.00	9.63405262955808	0.0267026042929838	-5.22687573560168	1.64028928409109	-3.18655726541431	0.00143976982380043	0.0105030592189133	Down	16	96435570	96450152	+	Gm49907	predicted gene%2C 49907 [Source:MGI Symbol%3BAcc:MGI:6270606]	-	-	-	-	-
ENSMUSG00000027257	4327	2	0.02	11	0.14	41	0.44	28	0.39	20.4544501265055	5.41263500919386	2.4363311059207	0.765050699246773	3.18453549329394	0.00144986529604738	0.0105573016432695	Ups	2	91086299	91095024	+	Pacsin3	protein kinase C and casein kinase substrate in neurons 3 [Source:MGI Symbol%3BAcc:MGI:1891410]	GO:0007010:cytoskeleton organization;GO:0006897:endocytosis;GO:0051926:negative regulation of calcium ion transport;GO:0045806:negative regulation of endocytosis;GO:0097320:membrane tubulation;GO:0051044:positive regulation of membrane protein ectodomain proteolysis;GO:0030100:regulation of endocytosis;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005768:endosome;GO:0005886:plasma membrane;	GO:0019855:calcium channel inhibitor activity;GO:0008092:cytoskeletal protein binding;GO:0042802:identical protein binding;GO:0008289:lipid binding;GO:0005543:phospholipid binding;	-	-
ENSMUSG00000019990	12444	19	0.08	18	0.08	1	0.00	1	0.00	9.48260781089213	0.0563004503783542	-4.15070972650973	1.30468652756043	-3.18138467657126	0.00146572865447899	0.0106468418700999	Down	10	20273750	20600824	-	Pde7b	phosphodiesterase 7B [Source:MGI Symbol%3BAcc:MGI:1352752]	GO:0006198:cAMP catabolic process;GO:0019933:cAMP-mediated signaling;GO:0007165:signal transduction;	-	GO:0004115:3',5'-cyclic-AMP phosphodiesterase activity;GO:0004114:3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0046872:metal ion binding;	K18436	;ko00230 Purine metabolism;ko01100 Metabolic pathways;ko05032 Morphine addiction;
ENSMUSG00000038349	6687	45	0.35	46	0.39	18	0.12	4	0.04	27.3472024766487	0.243140732722366	-2.04013649039805	0.642146994484804	-3.17705526603742	0.00148778681496637	0.0107764397830394	Down	1	55445080	55793444	+	Plcl1	phospholipase C-like 1 [Source:MGI Symbol%3BAcc:MGI:3036262]	GO:0007214:gamma-aminobutyric acid signaling pathway;GO:0006629:lipid metabolic process;GO:0048015:phosphatidylinositol-mediated signaling;GO:1900122:positive regulation of receptor binding;GO:0033135:regulation of peptidyl-serine phosphorylation;GO:0032228:regulation of synaptic transmission, GABAergic;	GO:0005737:cytoplasm;GO:0005886:plasma membrane;	GO:0050811:GABA receptor binding;GO:0070679:inositol 1,4,5 trisphosphate binding;GO:0004435:phosphatidylinositol phospholipase C activity;	K15375	;ko04727 GABAergic synapse;
ENSMUSG00000032609	8419	94	0.58	99	0.67	49	0.27	35	0.25	67.9084187651925	0.449781393402518	-1.15270411407653	0.363202909008631	-3.17371938793899	0.00150499115607962	0.0108856294279835	Down	9	108324835	108338780	-	Klhdc8b	kelch domain containing 8B [Source:MGI Symbol%3BAcc:MGI:1925517]	GO:1902410:mitotic cytokinetic process;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0045171:intercellular bridge;GO:0030496:midbody;	-	-	-
ENSMUSG00000106547	3645	25	0.36	19	0.30	3	0.04	2	0.03	11.8860646120219	0.117980849096139	-3.08337539764177	0.972708422845105	-3.16988660242409	0.00152498439533768	0.0110094683230264	Down	5	146125430	146131619	-	B230303O12Rik	RIKEN cDNA B230303O12 gene [Source:MGI Symbol%3BAcc:MGI:2442644]	-	-	-	-	-
ENSMUSG00000068740	12028	39	0.17	22	0.10	68	0.26	86	0.43	54.3198682095363	2.68389285723268	1.42432707935315	0.44949988176951	3.16869288985376	0.00153126103011559	0.0110443822369673	Ups	3	108298167	108323383	-	Celsr2	cadherin%2C EGF LAG seven-pass G-type receptor 2 [Source:MGI Symbol%3BAcc:MGI:1858235]	GO:0098609:cell-cell adhesion;GO:0033326:cerebrospinal fluid secretion;GO:0060271:cilium morphogenesis;GO:0003341:cilium movement;GO:0048813:dendrite morphogenesis;GO:0007156:homophilic cell adhesion via plasma membrane adhesion molecules;GO:0021999:neural plate anterior/posterior regionalization;GO:0001764:neuron migration;GO:0022407:regulation of cell-cell adhesion;GO:0032880:regulation of protein localization;GO:0006355:regulation of transcription, DNA-templated;GO:0021591:ventricular system development;GO:0016055:Wnt signaling pathway;	GO:0005737:cytoplasm;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0005509:calcium ion binding;GO:0004930:G-protein coupled receptor activity;	K04601	-
ENSMUSG00000031493	2800	23	0.43	32	0.65	4	0.07	5	0.11	15.7259991410535	0.170869398751734	-2.54903404908555	0.805881750708934	-3.16303731514352	0.00156132317576299	0.0112189923041938	Down	7	28869635	28873401	+	Ggn	gametogenetin [Source:MGI Symbol%3BAcc:MGI:2181461]	GO:0030154:cell differentiation;GO:0006302:double-strand break repair;GO:0007566:embryo implantation;GO:0007276:gamete generation;GO:0008104:protein localization;GO:0065003:macromolecular complex assembly;GO:0007283:spermatogenesis;	GO:0031410:cytoplasmic vesicle;GO:0016021:integral component of membrane;GO:0005635:nuclear envelope;GO:0005730:nucleolus;GO:0048471:perinuclear region of cytoplasm;	GO:0042802:identical protein binding;GO:0031625:ubiquitin protein ligase binding;	-	-
ENSMUSG00000105419	1968	20	0.53	30	0.87	5	0.12	2	0.06	13.9117516513409	0.142739829688419	-2.80854013865678	0.888919448277137	-3.15949903458651	0.00158040624036865	0.0113401728075868	Down	3	36151326	36153293	+	Gm43205	predicted gene 43205 [Source:MGI Symbol%3BAcc:MGI:5663342]	-	-	-	-	-
ENSMUSG00000040367	2951	1	0.02	2	0.04	18	0.28	18	0.36	9.89561746086346	12.5329878336308	3.64765848551769	1.15637042202727	3.15440313591114	0.00160826756701483	0.0114703138942351	Ups	5	3895173	3916596	+	Lrrd1	leucine rich repeats and death domain containing 1 [Source:MGI Symbol%3BAcc:MGI:3045299]	GO:0046579:positive regulation of Ras protein signal transduction;GO:0007165:signal transduction;	-	-	-	-
ENSMUSG00000037989	8481	0	0.00	1	0.01	19	0.10	17	0.12	9.36088373047521	37.4597963506641	5.22727115131067	1.65917723327058	3.15052005686375	0.00162980065851118	0.0115687072981344	Ups	13	49189779	49301490	-	Wnk2	WNK lysine deficient protein kinase 2 [Source:MGI Symbol%3BAcc:MGI:1922857]	GO:0035556:intracellular signal transduction;GO:0050801:ion homeostasis;GO:0008285:negative regulation of cell proliferation;GO:0070373:negative regulation of ERK1 and ERK2 cascade;GO:0010766:negative regulation of sodium ion transport;GO:0090263:positive regulation of canonical Wnt signaling pathway;GO:1903288:positive regulation of potassium ion import;GO:2000651:positive regulation of sodium ion transmembrane transporter activity;GO:0046777:protein autophosphorylation;GO:0006468:protein phosphorylation;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005886:plasma membrane;	GO:0005524:ATP binding;GO:0019869:chloride channel inhibitor activity;GO:0019870:potassium channel inhibitor activity;GO:0004674:protein serine/threonine kinase activity;	K08867	-
ENSMUSG00000120961	2001	27	0.70	30	0.85	4	0.09	6	0.18	16.449385169538	0.18445037430367	-2.43869537820215	0.775271276606547	-3.14560264489174	0.00165745022749309	0.0117229436293261	Down	16	55932346	55936675	-	-	novel transcript%2C antisense to Senp7	-	-	-	-	-
ENSMUSG00000047656	1144	43	1.95	61	3.03	150	6.03	82	4.27	82.7249426057828	2.27084010051195	1.18322612334112	0.376174296566612	3.14541991342993	0.00165848595668238	0.0117248610695102	Ups	19	6973499	6976414	+	Trpt1	tRNA phosphotransferase 1 [Source:MGI Symbol%3BAcc:MGI:1333115]	GO:0045859:regulation of protein kinase activity;GO:0008033:tRNA processing;GO:0006388:tRNA splicing, via endonucleolytic cleavage and ligation;	-	GO:0003950:NAD+ ADP-ribosyltransferase activity;GO:0000215:tRNA 2'-phosphotransferase activity;	K10669	-
ENSMUSG00000052584	1388	14	0.52	22	0.90	60	1.99	46	1.97	35.4205083407615	3.03853880346835	1.60337771584674	0.509906512945592	3.14445427767624	0.00166396911363767	0.0117527878344174	Ups	14	76770254	76794329	-	Serp2	stress-associated endoplasmic reticulum protein family member 2 [Source:MGI Symbol%3BAcc:MGI:1919911]	GO:0030968:endoplasmic reticulum unfolded protein response;GO:0006486:protein glycosylation;GO:0015031:protein transport;	GO:0005789:endoplasmic reticulum membrane;GO:0016021:integral component of membrane;	-	-	-
ENSMUSG00000055421	6783	1	0.01	4	0.03	19	0.13	23	0.20	12.0201374259386	8.8078033428443	3.13878225733659	0.998790879230405	3.14258201852534	0.00167464788572291	0.0118064600826093	Ups	14	93250846	94128115	-	Pcdh9	protocadherin 9 [Source:MGI Symbol%3BAcc:MGI:1306801]	GO:0007155:cell adhesion;GO:0030900:forebrain development;GO:0007156:homophilic cell adhesion via plasma membrane adhesion molecules;	GO:0044291:cell-cell contact zone;GO:0030426:growth cone;GO:0005887:integral component of plasma membrane;	GO:0005509:calcium ion binding;	K16498	-
ENSMUSG00000039238	3232	1	0.02	0	0.00	21	0.30	15	0.28	9.24856617947789	37.2576916446206	5.21946638763117	1.66312233415604	3.13835385433617	0.00169899635536285	0.0119506468408871	Ups	11	121401804	121410159	-	Zfp750	zinc finger protein 750 [Source:MGI Symbol%3BAcc:MGI:2442210]	GO:0030154:cell differentiation;GO:0008544:epidermis development;GO:0010719:negative regulation of epithelial to mesenchymal transition;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;	GO:0005634:nucleus;	GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001227:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0046872:metal ion binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	-	-
ENSMUSG00000115793	2859	35	0.64	30	0.60	8	0.13	6	0.12	19.2554926191959	0.223621818369607	-2.1608671387367	0.68915735453087	-3.13552068265696	0.00171549331316999	0.0120445853773574	Down	15	35860656	35863514	+	Gm48961	predicted gene%2C 48961 [Source:MGI Symbol%3BAcc:MGI:6118294]	-	-	-	-	-
ENSMUSG00000051236	4048	42	0.54	59	0.83	21	0.24	6	0.09	31.131792464976	0.268784188301794	-1.89547982332403	0.60488205480145	-3.1336354059077	0.00172655237428352	0.0121058751959188	Down	10	120617001	120735006	-	Msrb3	methionine sulfoxide reductase B3 [Source:MGI Symbol%3BAcc:MGI:2443538]	GO:0030091:protein repair;GO:0006979:response to oxidative stress;	GO:0005737:cytoplasm;GO:0005783:endoplasmic reticulum;GO:0005739:mitochondrion;	GO:0033745:L-methionine-(R)-S-oxide reductase activity;GO:0033743:peptide-methionine (R)-S-oxide reductase activity;GO:0008270:zinc ion binding;	K07305	-
ENSMUSG00000107017	2114	47	1.15	38	1.02	16	0.35	2	0.06	24.8044536025971	0.211716213049745	-2.23979634093709	0.714761216419323	-3.13362881125197	0.00172659117343644	0.0121058751959188	Down	6	3325742	3327855	-	Gm43196	predicted gene 43196 [Source:MGI Symbol%3BAcc:MGI:5663333]	-	-	-	-	-
ENSMUSG00000057457	6291	21	0.17	11	0.10	42	0.31	59	0.56	33.8179859431825	3.36991533806145	1.75271234722519	0.55994316067975	3.13016118474858	0.00174710410623729	0.012216185300977	Ups	X	155945071	156198308	-	Phex	phosphate regulating endopeptidase homolog%2C X-linked [Source:MGI Symbol%3BAcc:MGI:107489]	GO:0060348:bone development;GO:0030282:bone mineralization;GO:0071374:cellular response to parathyroid hormone stimulus;GO:0071305:cellular response to vitamin D;GO:0030324:lung development;GO:0042476:odontogenesis;GO:0019637:organophosphate metabolic process;GO:0016485:protein processing;GO:0006508:proteolysis;GO:0060416:response to growth hormone;GO:1990418:response to insulin-like growth factor stimulus;	GO:0005783:endoplasmic reticulum;GO:0005794:Golgi apparatus;GO:0016021:integral component of membrane;GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;	GO:0046872:metal ion binding;GO:0004222:metalloendopeptidase activity;	K08636	-
ENSMUSG00000004891	6416	4	0.03	5	0.04	36	0.26	17	0.16	15.209424337557	5.97905984451448	2.57991865093027	0.824368744401119	3.12956873784013	0.00175063108877789	0.0122352676004194	Ups	3	87878385	87887758	+	Nes	nestin [Source:MGI Symbol%3BAcc:MGI:101784]	GO:0007420:brain development;GO:0048858:cell projection morphogenesis;GO:0031076:embryonic camera-type eye development;GO:0000086:G2/M transition of mitotic cell cycle;GO:0043086:negative regulation of catalytic activity;GO:0043524:negative regulation of neuron apoptotic process;GO:0032091:negative regulation of protein binding;GO:0007399:nervous system development;GO:0030844:positive regulation of intermediate filament depolymerization;GO:2000179:positive regulation of neural precursor cell proliferation;GO:0072089:stem cell proliferation;	GO:0005737:cytoplasm;GO:0005882:intermediate filament;	GO:0031730:CCR5 chemokine receptor binding;GO:0019215:intermediate filament binding;	K07609	-
ENSMUSG00000021176	5309	116	1.13	134	1.44	66	0.57	54	0.61	91.0423958152317	0.49763310781165	-1.00684562291011	0.321845445244034	-3.12835131827539	0.00175789924429969	0.0122804678870576	Down	12	99659304	99850698	-	Efcab11	EF-hand calcium binding domain 11 [Source:MGI Symbol%3BAcc:MGI:1926017]	-	-	GO:0005509:calcium ion binding;	-	-
ENSMUSG00000097604	2169	6	0.14	3	0.08	33	0.70	19	0.52	15.0507705278293	5.94500147982591	2.57167716908569	0.822238070670145	3.12765518992536	0.00176206767944388	0.0122931480133647	Ups	9	57905324	57914734	+	Gm17322	predicted gene%2C 17322 [Source:MGI Symbol%3BAcc:MGI:4936956]	-	-	-	-	-
ENSMUSG00000063275	2118	11	0.27	2	0.05	36	0.78	29	0.82	19.4610230685328	5.24603470076361	2.39122735057926	0.76461166450878	3.1273749297501	0.00176374844910548	0.0122989171071321	Ups	2	13855093	14060946	-	Hacd1	3-hydroxyacyl-CoA dehydratase 1 [Source:MGI Symbol%3BAcc:MGI:1353592]	GO:0034622:cellular macromolecular complex assembly;GO:0071529:cementum mineralization;GO:0030497:fatty acid elongation;GO:0014902:myotube differentiation;GO:0010811:positive regulation of cell-substrate adhesion;GO:2000045:regulation of G1/S transition of mitotic cell cycle;GO:0010389:regulation of G2/M transition of mitotic cell cycle;GO:0030148:sphingolipid biosynthetic process;GO:0042761:very long-chain fatty acid biosynthetic process;	GO:0005783:endoplasmic reticulum;GO:0030176:integral component of endoplasmic reticulum membrane;	GO:0018812:3-hydroxyacyl-CoA dehydratase activity;GO:0019899:enzyme binding;GO:0046848:hydroxyapatite binding;	K10703	;ko00062 Fatty acid elongation;ko01040 Biosynthesis of unsaturated fatty acids;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko01212 Fatty acid metabolism;
ENSMUSG00000021061	12147	65	0.28	49	0.23	126	0.48	99	0.49	84.14827735109	2.05212572330069	1.03711912023648	0.331721147256699	3.12647875727355	0.00176913285021233	0.01232525357799	Ups	12	76627262	76757321	-	Sptb	spectrin beta%2C erythrocytic [Source:MGI Symbol%3BAcc:MGI:98387]	GO:0051693:actin filament capping;GO:0030097:hemopoiesis;GO:0007009:plasma membrane organization;GO:0006779:porphyrin-containing compound biosynthetic process;	GO:0009986:cell surface;GO:0030863:cortical cytoskeleton;GO:0005829:cytosol;GO:0016020:membrane;GO:0005886:plasma membrane;GO:0032991:macromolecular complex;GO:0008091:spectrin;GO:0014731:spectrin-associated cytoskeleton;	GO:0003779:actin binding;GO:0051015:actin filament binding;GO:0030506:ankyrin binding;GO:0005200:structural constituent of cytoskeleton;	K06115	-
ENSMUSG00000052821	5142	28	0.28	25	0.28	5	0.04	4	0.05	15.1089463480364	0.176506440718143	-2.50220726650371	0.800922245611398	-3.12415753241265	0.00178314961565962	0.0123990302100917	Down	X	105617952	105647285	-	Cysltr1	cysteinyl leukotriene receptor 1 [Source:MGI Symbol%3BAcc:MGI:1926218]	GO:0006816:calcium ion transport;GO:0007166:cell surface receptor signaling pathway;GO:0006935:chemotaxis;GO:0006954:inflammatory response;GO:0002437:inflammatory response to antigenic stimulus;GO:0007218:neuropeptide signaling pathway;GO:0045766:positive regulation of angiogenesis;GO:0045907:positive regulation of vasoconstriction;	GO:0005887:integral component of plasma membrane;	GO:0001631:cysteinyl leukotriene receptor activity;GO:0008528:G-protein coupled peptide receptor activity;GO:0004974:leukotriene receptor activity;	K04322	;ko04020 Calcium signaling pathway;ko04080 Neuroactive ligand-receptor interaction;
ENSMUSG00000042500	6947	149	1.11	189	1.55	41	0.27	89	0.76	116.576026845391	0.413185214161262	-1.27513946662314	0.408704594503034	-3.11995383407336	0.00180879386161003	0.0125445703636039	Down	4	126383334	126427265	-	Ago4	argonaute RISC catalytic subunit 4 [Source:MGI Symbol%3BAcc:MGI:1924100]	GO:0008584:male gonad development;GO:0007140:male meiosis;GO:0035280:miRNA loading onto RISC involved in gene silencing by miRNA;GO:0035278:negative regulation of translation involved in gene silencing by miRNA;GO:0010586:miRNA metabolic process;GO:0006402:mRNA catabolic process;GO:0043066:negative regulation of apoptotic process;GO:0031054:pre-miRNA processing;GO:0035196:production of miRNAs involved in gene silencing by miRNA;GO:0022604:regulation of cell morphogenesis;GO:0010501:RNA secondary structure unwinding;GO:0007130:synaptonemal complex assembly;	GO:0005737:cytoplasm;GO:0036464:cytoplasmic ribonucleoprotein granule;GO:0005829:cytosol;GO:0005634:nucleus;GO:0000932:cytoplasmic mRNA processing body;GO:0016442:RISC complex;GO:0070578:RISC-loading complex;GO:0016020:membrane;	GO:0003725:double-stranded RNA binding;GO:0035198:miRNA binding;GO:0003723:RNA binding;GO:0003727:single-stranded RNA binding;	K11593	;ko04361 Axon regeneration;
ENSMUSG00000068227	4287	121	1.47	120	1.59	68	0.73	48	0.67	87.5125599145938	0.497488685154435	-1.00726438140639	0.323039881658139	-3.11808057951291	0.00182033027435941	0.0126017807796963	Down	15	78363456	78379471	-	Il2rb	interleukin 2 receptor%2C beta chain [Source:MGI Symbol%3BAcc:MGI:96550]	GO:0019221:cytokine-mediated signaling pathway;GO:0035723:interleukin-15-mediated signaling pathway;GO:0038110:interleukin-2-mediated signaling pathway;GO:0030101:natural killer cell activation;GO:0043066:negative regulation of apoptotic process;GO:0050766:positive regulation of phagocytosis;	GO:0009986:cell surface;GO:0009897:external side of plasma membrane;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0042010:interleukin-15 receptor activity;GO:0019976:interleukin-2 binding;GO:0004911:interleukin-2 receptor activity;	K05069	;ko04060 Cytokine-cytokine receptor interaction;ko04061 Viral protein interaction with cytokine and cytokine receptor;ko04144 Endocytosis;ko04151 PI3K-Akt signaling pathway;ko04630 JAK-STAT signaling pathway;ko04658 Th1 and Th2 cell differentiation;ko04659 Th17 cell differentiation;ko05162 Measles;ko05166 Human T-cell leukemia virus 1 infection;ko05200 Pathways in cancer;ko05202 Transcriptional misregulation in cancer;
ENSMUSG00000048534	3108	182	3.04	102	1.87	75	1.11	52	1.00	100.132601474259	0.464817546271888	-1.10526356521194	0.354542305666827	-3.11743774310135	0.00182430473074752	0.0126179020032848	Down	9	44990481	45019832	+	Jaml	junction adhesion molecule like [Source:MGI Symbol%3BAcc:MGI:2685484]	GO:0046629:gamma-delta T cell activation;GO:0007157:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0035696:monocyte extravasation;GO:0030593:neutrophil chemotaxis;GO:0072672:neutrophil extravasation;GO:0060054:positive regulation of epithelial cell proliferation involved in wound healing;	GO:0005923:bicellular tight junction;GO:0016021:integral component of membrane;GO:0005654:nucleoplasm;GO:0005886:plasma membrane;	GO:0050839:cell adhesion molecule binding;GO:0005178:integrin binding;GO:0042803:protein homodimerization activity;	-	-
ENSMUSG00000120382	1059	37	1.81	43	2.31	93	4.04	80	4.50	63.1599093793979	2.24715966639764	1.16810263530394	0.375014076091679	3.11482344203629	0.00184055043068418	0.0127130632000501	Ups	7	98306100	98307158	+	-	novel transcript	-	-	-	-	-
ENSMUSG00000117661	3226	2	0.03	4	0.07	23	0.33	20	0.37	12.3379102110123	7.43442109558806	2.89422040669727	0.929915625252862	3.11234732281252	0.00185605991434738	0.0128028892157457	Ups	18	78520093	78523928	+	4931439C15Rik	RIKEN cDNA 4931439C15 gene [Source:MGI Symbol%3BAcc:MGI:1921617]	-	-	-	-	-
ENSMUSG00000097090	1650	56	1.76	82	2.83	22	0.61	26	0.94	45.9861024721727	0.363799190198289	-1.45878576327293	0.469965039487484	-3.10403038673641	0.00190903723111088	0.0130870550961663	Down	17	27420006	27422045	+	Gm26724	predicted gene%2C 26724 [Source:MGI Symbol%3BAcc:MGI:5477218]	-	-	-	-	-
ENSMUSG00000020689	5901	170	1.50	245	2.36	82	0.64	112	1.13	151.347197582619	0.492972598489836	-1.02042063717157	0.329350915470437	-3.09827782234649	0.00194648859596863	0.013306935412654	Down	11	104498826	104561302	+	Itgb3	integrin beta 3 [Source:MGI Symbol%3BAcc:MGI:96612]	GO:0032147:activation of protein kinase activity;GO:0038027:apolipoprotein A-I-mediated signaling pathway;GO:0043277:apoptotic cell clearance;GO:0033627:cell adhesion mediated by integrin;	GO:0071133:alpha9-beta1 integrin-ADAM8 complex;GO:0035868:alphav-beta3 integrin-HMGB1 complex;GO:0035867:alphav-beta3 integrin-IGF-1-IGF1R complex;GO:0035866:alphav-beta3 integrin-PKCalpha complex;	GO:0050839:cell adhesion molecule binding;GO:0019899:enzyme binding;GO:0050840:extracellular matrix binding;GO:0001968:fibronectin binding;	K06493	;ko04015 Rap1 signaling pathway;ko04145 Phagosome;ko04151 PI3K-Akt signaling pathway;ko04380 Osteoclast differentiation;ko04510 Focal adhesion;ko04512 ECM-receptor interaction;ko04611 Platelet activation;ko04613 Neutrophil extracellular trap formation;ko04640 Hematopoietic cell lineage;ko04810 Regulation of actin cytoskeleton;ko04919 Thyroid hormone signaling pathway;ko05163 Human cytomegalovirus infection;ko05165 Human papillomavirus infection;ko05168 Herpes simplex virus 1 infection;ko05205 Proteoglycans in cancer;ko05206 MicroRNAs in cancer;ko05410 Hypertrophic cardiomyopathy;ko05412 Arrhythmogenic right ventricular cardiomyopathy;ko05414 Dilated cardiomyopathy;ko05418 Fluid shear stress and atherosclerosis;
ENSMUSG00000121126	620	7	0.59	5	0.46	20	1.48	39	3.75	18.3804426430108	5.29959265493982	2.40588147339602	0.776842028832232	3.0970022013518	0.00195488422151826	0.0133464802550138	Ups	12	55444872	55445491	-	-	novel transcript%2C antisense to Psma6	-	-	-	-	-
ENSMUSG00000050199	5884	72	0.64	51	0.49	131	1.02	107	1.08	89.6803792983917	2.0162381721369	1.01166607012017	0.326916488217422	3.094570346196	0.00197098188473692	0.0134444111301405	Ups	2	109747992	109844602	+	Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4 [Source:MGI Symbol%3BAcc:MGI:1891468]	GO:0007411:axon guidance;GO:0030282:bone mineralization;GO:0046849:bone remodeling;GO:0061290:canonical Wnt signaling pathway involved in metanephric kidney development;GO:0072202:cell differentiation involved in metanephros development;GO:0032922:circadian regulation of gene expression;GO:0007623:circadian rhythm;GO:0048565:digestive tract development;GO:0050673:epithelial cell proliferation;GO:2001013:epithelial cell proliferation involved in renal tubule morphogenesis;GO:0007186:G-protein coupled receptor signaling pathway;GO:0001942:hair follicle development;GO:0045087:innate immune response;GO:0036335:intestinal stem cell homeostasis;GO:0030539:male genitalia development;GO:0072224:metanephric glomerulus development;GO:0072282:metanephric nephron tubule morphogenesis;GO:0050919:negative chemotaxis;GO:0001818:negative regulation of cytokine production;GO:0034122:negative regulation of toll-like receptor signaling pathway;GO:0045892:negative regulation of transcription, DNA-templated;GO:0001649:osteoblast differentiation;GO:0090190:positive regulation of branching involved in ureteric bud morphogenesis;GO:0090263:positive regulation of canonical Wnt signaling pathway;GO:0045893:positive regulation of transcription, DNA-templated;GO:0007283:spermatogenesis;GO:0035239:tube morphogenesis;	GO:0005887:integral component of plasma membrane;	GO:0008201:heparin binding;GO:0016500:protein-hormone receptor activity;GO:0048495:Roundabout binding;GO:0004888:transmembrane signaling receptor activity;	K04309	;ko04310 Wnt signaling pathway;
ENSMUSG00000120256	482	3	0.32	1	0.12	22	2.10	16	1.98	10.4787810851893	9.87089087615676	3.30318029791494	1.06789469689687	3.09317042917568	0.00198030373003141	0.0134959899539119	Ups	4	128915012	128926512	-	-	novel transcript	-	-	-	-	-
ENSMUSG00000111927	1357	51	1.95	51	2.14	19	0.64	14	0.61	33.0311530366733	0.335008800306032	-1.57772910083602	0.510628411332292	-3.08977931078988	0.00200305268855088	0.0135666121582329	Down	10	17398361	17402662	-	Gm47770	predicted gene%2C 47770 [Source:MGI Symbol%3BAcc:MGI:6096926]	-	-	-	-	-
ENSMUSG00000022856	1360	62	2.37	40	1.67	122	4.13	89	3.90	77.4841544112458	2.14771521841285	1.10280270830408	0.357604029301371	3.08386544317904	0.00204329987889331	0.0138087088333847	Ups	16	21753076	21766302	-	Tmem41a	transmembrane protein 41a [Source:MGI Symbol%3BAcc:MGI:1913914]	-	GO:0016021:integral component of membrane;	-	-	-
ENSMUSG00000034738	1888	56	1.54	48	1.45	19	0.46	15	0.47	33.7408192213863	0.339773577346013	-1.55735442986976	0.505081137774071	-3.08337475585235	0.00204667239602668	0.0138193194718948	Down	2	68966144	69019674	+	Nostrin	nitric oxide synthase trafficker [Source:MGI Symbol%3BAcc:MGI:3606242]	GO:0006897:endocytosis;GO:0045892:negative regulation of transcription, DNA-templated;GO:0007165:signal transduction;	GO:0031410:cytoplasmic vesicle;GO:0005856:cytoskeleton;GO:0005634:nucleus;GO:0005886:plasma membrane;	GO:0003677:DNA binding;	-	-
ENSMUSG00000044576	3865	0	0.00	4	0.06	32	0.38	12	0.18	11.7016161785157	10.9545308749557	3.45345579748417	1.12176862779438	3.07858119037821	0.00207988846998646	0.013988162192444	Ups	5	30310159	30323376	+	Garem2	GRB2 associated regulator of MAPK1 subtype 2 [Source:MGI Symbol%3BAcc:MGI:2685290]	-	-	-	-	-
ENSMUSG00000071648	1517	97	3.32	99	3.71	53	1.61	35	1.37	69.5352386323407	0.462975259112482	-1.11099299537469	0.361124558841019	-3.07648141943121	0.00209459356865977	0.0140321905513674	Down	19	8904755	8906720	-	Rom1	rod outer segment membrane protein 1 [Source:MGI Symbol%3BAcc:MGI:97998]	GO:0060219:camera-type eye photoreceptor cell differentiation;GO:0007155:cell adhesion;GO:0050908:detection of light stimulus involved in visual perception;GO:0035845:photoreceptor cell outer segment organization;GO:0051291:protein heterooligomerization;GO:0051260:protein homooligomerization;GO:1903546:protein localization to photoreceptor outer segment;GO:0010468:regulation of gene expression;GO:0060041:retina development in camera-type eye;GO:0060042:retina morphogenesis in camera-type eye;GO:0061298:retina vasculature development in camera-type eye;	GO:0005887:integral component of plasma membrane;GO:0001750:photoreceptor outer segment;GO:0042622:photoreceptor outer segment membrane;	GO:0042803:protein homodimerization activity;	K17344	-
ENSMUSG00000085337	2745	76	1.44	45	0.93	185	3.10	86	1.87	95.674859647438	2.28518110146968	1.19230850394369	0.387557280273458	3.07647040742573	0.0020946709385731	0.0140321905513674	Ups	16	91408356	91420749	+	Gm15964	predicted gene 15964 [Source:MGI Symbol%3BAcc:MGI:3802003]	-	-	-	-	-
ENSMUSG00000063698	2975	88	1.54	126	2.41	52	0.80	42	0.84	75.8750726629593	0.45401818366877	-1.13917801551342	0.370595142115787	-3.0739151328581	0.00211269523449254	0.0141405799763023	Down	19	60825715	60849917	-	Sfxn4	sideroflexin 4 [Source:MGI Symbol%3BAcc:MGI:2137680]	GO:0006865:amino acid transport;GO:1990542:mitochondrial transmembrane transport;	GO:0031305:integral component of mitochondrial inner membrane;GO:0005739:mitochondrion;	GO:0015075:ion transmembrane transporter activity;GO:0022857:transmembrane transporter activity;	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000038623	5921	534	4.68	681	6.55	126	0.98	221	2.22	386.549847612158	0.305924055723915	-1.70875454010279	0.556736234400377	-3.06923536590568	0.00214607442539119	0.0143202372667313	Down	7	81508749	81534182	+	Tm6sf1	transmembrane 6 superfamily member 1 [Source:MGI Symbol%3BAcc:MGI:1933209]	-	GO:0016021:integral component of membrane;GO:0005765:lysosomal membrane;	-	-	-
ENSMUSG00000024354	3238	98	1.57	90	1.58	54	0.77	18	0.33	63.0098301243926	0.38681273800479	-1.37029279036797	0.447023432687817	-3.06537127624118	0.00217399937238759	0.0144813668011257	Down	18	35747657	35760297	-	Slc23a1	solute carrier family 23 (nucleobase transporters)%2C member 1 [Source:MGI Symbol%3BAcc:MGI:1341903]	GO:0007420:brain development;GO:0070837:dehydroascorbic acid transport;GO:0015882:L-ascorbic acid transport;GO:0030324:lung development;GO:0009636:response to toxic substance;GO:0006814:sodium ion transport;GO:0070904:transepithelial L-ascorbic acid transport;	GO:0016324:apical plasma membrane;GO:0009925:basal plasma membrane;GO:0005903:brush border;GO:0005737:cytoplasm;GO:0016021:integral component of membrane;GO:0043229:intracellular organelle;GO:0005886:plasma membrane;	GO:0033300:dehydroascorbic acid transporter activity;GO:0008520:L-ascorbate:sodium symporter activity;GO:0015229:L-ascorbic acid transporter activity;GO:0015081:sodium ion transmembrane transporter activity;	K14611	;ko04977 Vitamin digestion and absorption;
ENSMUSG00000110386	1885	12	0.33	2181	65.84	12	0.29	3	0.09	550.753586956307	0.00658823432215766	-7.24589241669512	2.36427002184658	-3.06474825199358	0.00217853289176815	0.0145052641608219	Down	8	85852501	85858918	-	Gm42031	predicted gene%2C 42031 [Source:MGI Symbol%3BAcc:MGI:5624916]	-	-	-	-	-
ENSMUSG00000103632	427	58	7.05	51	6.80	155	16.70	78	10.88	83.7996481655368	2.18015032391783	1.12442761394433	0.366946767718619	3.06427992521946	0.00218194643803533	0.0145090922293295	Ups	1	160555304	160555730	-	Gm38329	predicted gene%2C 38329 [Source:MGI Symbol%3BAcc:MGI:5611557]	-	-	-	-	-
ENSMUSG00000029314	3502	79	1.17	63	1.02	26	0.34	28	0.48	48.1463241902122	0.399322375326151	-1.32437418177525	0.432607192573993	-3.06137809197133	0.00220320689338259	0.0146250971875016	Down	5	100993579	101046968	+	Gpat3	glycerol-3-phosphate acyltransferase 3 [Source:MGI Symbol%3BAcc:MGI:3603816]	GO:0016024:CDP-diacylglycerol biosynthetic process;GO:0006072:glycerol-3-phosphate metabolic process;GO:0008654:phospholipid biosynthetic process;GO:0032006:regulation of TOR signaling;GO:0019432:triglyceride biosynthetic process;	GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0016021:integral component of membrane;	GO:0003841:1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0004366:glycerol-3-phosphate O-acyltransferase activity;	K13506	;ko00561 Glycerolipid metabolism;ko00564 Glycerophospholipid metabolism;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;
ENSMUSG00000103409	1653	16	0.50	8	0.28	70	1.95	24	0.86	28.5558235975261	3.95677740211524	1.98432590536683	0.648384436175323	3.06041569577446	0.00221029976502593	0.0146658315001764	Ups	9	107469829	107474274	-	Lsmem2	leucine-rich single-pass membrane protein 2 [Source:MGI Symbol%3BAcc:MGI:3612240]	-	GO:0016021:integral component of membrane;	-	-	-
ENSMUSG00000025746	2428	29	0.62	46	1.08	77	1.46	99	2.43	63.64789503508	2.47167671464372	1.30549005688277	0.426630476797473	3.06000187019573	0.00221335609361137	0.0146734121657746	Ups	5	30218112	30224979	+	Il6	interleukin 6 [Source:MGI Symbol%3BAcc:MGI:96559]	GO:0006953:acute-phase response;GO:0007568:aging;GO:0046849:bone remodeling;GO:0060445:branching involved in salivary gland morphogenesis;	GO:0005737:cytoplasm;GO:0009897:external side of plasma membrane;GO:0005615:extracellular space;GO:0005896:interleukin-6 receptor complex;	GO:0005125:cytokine activity;GO:0008083:growth factor activity;GO:0005138:interleukin-6 receptor binding;GO:0005102:receptor binding;	K05405	;ko01521 EGFR tyrosine kinase inhibitor resistance;ko01523 Antifolate resistance;ko04060 Cytokine-cytokine receptor interaction;ko04061 Viral protein interaction with cytokine and cytokine receptor;ko04066 HIF-1 signaling pathway;ko04068 FoxO signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04218 Cellular senescence;ko04620 Toll-like receptor signaling pathway;ko04621 NOD-like receptor signaling pathway;ko04623 Cytosolic DNA-sensing pathway;ko04625 C-type lectin receptor signaling pathway;ko04630 JAK-STAT signaling pathway;ko04640 Hematopoietic cell lineage;ko04657 IL-17 signaling pathway;ko04659 Th17 cell differentiation;ko04668 TNF signaling pathway;ko04672 Intestinal immune network for IgA production;ko04931 Insulin resistance;ko04932 Non-alcoholic fatty liver disease;ko04933 AGE-RAGE signaling pathway in diabetic complications;ko05010 Alzheimer disease;ko05020 Prion disease;ko05022 Pathways of neurodegeneration - multiple diseases;ko05130 Pathogenic Escherichia coli infection;ko05132 Salmonella infection;ko05133 Pertussis;ko05134 Legionellosis;ko05135 Yersinia infection;ko05142 Chagas disease;ko05143 African trypanosomiasis;ko05144 Malaria;ko05146 Amoebiasis;ko05152 Tuberculosis;ko05161 Hepatitis B;ko05162 Measles;ko05163 Human cytomegalovirus infection;ko05164 Influenza A;ko05166 Human T-cell leukemia virus 1 infection;ko05167 Kaposi sarcoma-associated herpesvirus infection;ko05168 Herpes simplex virus 1 infection;ko05169 Epstein-Barr virus infection;ko05171 Coronavirus disease - COVID-19;ko05200 Pathways in cancer;ko05202 Transcriptional misregulation in cancer;ko05321 Inflammatory bowel disease;ko05323 Rheumatoid arthritis;ko05332 Graft-versus-host disease;ko05410 Hypertrophic cardiomyopathy;
ENSMUSG00000037410	8799	22	0.13	35	0.23	74	0.39	66	0.45	49.3514534285505	2.54879601670001	1.34981591731028	0.441561253569161	3.05691658042831	0.00223626501475208	0.0147861085951642	Ups	9	90084080	90152857	-	Tbc1d2b	TBC1 domain family%2C member 2B [Source:MGI Symbol%3BAcc:MGI:1914266]	GO:0090630:activation of GTPase activity;GO:0006886:intracellular protein transport;	GO:0005829:cytosol;	GO:0005096:GTPase activator activity;	-	-
ENSMUSG00000073633	2148	35	0.85	35	0.93	11	0.24	6	0.17	21.1928149087947	0.249705680064389	-2.00169945621025	0.654834092951203	-3.05680397181064	0.00223710525243125	0.0147861085951642	Down	1	84817562	84878208	+	Fbxo36	F-box protein 36 [Source:MGI Symbol%3BAcc:MGI:1289192]	-	-	-	K10312	-
ENSMUSG00000038141	6548	76	0.60	90	0.78	42	0.30	27	0.25	57.5752189556344	0.427556973594037	-1.22581141747385	0.401439898447708	-3.05353658720478	0.00226161141857706	0.0149352064997677	Down	17	6307135	6358589	+	Tmem181a	transmembrane protein 181A [Source:MGI Symbol%3BAcc:MGI:1924356]	-	GO:0016021:integral component of membrane;	GO:0015643:toxic substance binding;	-	-
ENSMUSG00000074361	3561	44	0.64	34	0.54	14	0.18	6	0.10	23.7553906852706	0.262743043587255	-1.92827552714149	0.631915421338196	-3.0514772420936	0.00227718310339441	0.0150315650914549	Down	7	15968510	15978079	-	C5ar2	complement component 5a receptor 2 [Source:MGI Symbol%3BAcc:MGI:2442013]	GO:0006935:chemotaxis;GO:0002430:complement receptor mediated signaling pathway;GO:0006954:inflammatory response;GO:0032715:negative regulation of interleukin-6 production;GO:0090024:negative regulation of neutrophil chemotaxis;GO:0032720:negative regulation of tumor necrosis factor production;GO:0007200:phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007204:positive regulation of cytosolic calcium ion concentration;GO:0050679:positive regulation of epithelial cell proliferation;GO:0070374:positive regulation of ERK1 and ERK2 cascade;GO:0032677:regulation of interleukin-8 production;	GO:0045177:apical part of cell;GO:0009925:basal plasma membrane;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0004878:complement component C5a receptor activity;GO:0004875:complement receptor activity;GO:0004930:G-protein coupled receptor activity;	K04171	-
ENSMUSG00000091438	581	0	0.00	1	0.10	10	0.79	24	2.46	9.24635204694444	36.7685253861933	5.20039941282955	1.70515222645176	3.04981533739719	0.00228982109951959	0.0150901656968388	Ups	6	134145842	134148970	-	Gm17088	predicted gene 17088 [Source:MGI Symbol%3BAcc:MGI:4937915]	-	-	-	-	-
ENSMUSG00000028347	2549	71	1.45	52	1.16	26	0.47	18	0.42	40.7230062649539	0.370988028110354	-1.43055546347121	0.469136532714025	-3.04933716245722	0.00229346927700236	0.0151000677945703	Down	4	48585174	48663131	+	Tmeff1	transmembrane protein with EGF-like and two follistatin-like domains 1 [Source:MGI Symbol%3BAcc:MGI:1926810]	GO:0009887:organ morphogenesis;GO:0007528:neuromuscular junction development;GO:0043113:receptor clustering;GO:0009888:tissue development;	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	-	-	-
ENSMUSG00000020826	4439	1	0.01	3	0.04	17	0.18	20	0.27	10.4736043577733	9.70236734946273	3.27833680365303	1.0753446651418	3.04863818078341	0.00229881165263767	0.0151222556334389	Ups	11	78811613	78851080	+	Nos2	nitric oxide synthase 2%2C inducible [Source:MGI Symbol%3BAcc:MGI:97361]	GO:0007568:aging;GO:0006527:arginine catabolic process;GO:0001974:blood vessel remodeling;GO:0071345:cellular response to cytokine stimulus;GO:0035690:cellular response to drug;GO:0071346:cellular response to interferon-gamma;GO:0071222:cellular response to lipopolysaccharide;GO:0071407:cellular response to organic cyclic compound;GO:0007623:circadian rhythm;GO:0042742:defense response to bacterium;GO:0006954:inflammatory response;GO:0045776:negative regulation of blood pressure;GO:0010629:negative regulation of gene expression;GO:0042177:negative regulation of protein catabolic process;GO:0006809:nitric oxide biosynthetic process;GO:0007263:nitric oxide mediated signal transduction;GO:0018119:peptidyl-cysteine S-nitrosylation;GO:0031284:positive regulation of guanylate cyclase activity;GO:0032755:positive regulation of interleukin-6 production;GO:0032757:positive regulation of interleukin-8 production;GO:0051712:positive regulation of killing of cells of other organism;GO:0032310:prostaglandin secretion;GO:0042127:regulation of cell proliferation;GO:1900015:regulation of cytokine production involved in inflammatory response;GO:0050796:regulation of insulin secretion;GO:0009617:response to bacterium;GO:0009725:response to hormone;GO:0001666:response to hypoxia;GO:0032496:response to lipopolysaccharide;GO:0006801:superoxide metabolic process;	GO:0030863:cortical cytoskeleton;GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005615:extracellular space;GO:0005634:nucleus;GO:0048471:perinuclear region of cytoplasm;GO:0005777:peroxisome;GO:0005886:plasma membrane;GO:0012506:vesicle membrane;	GO:0003779:actin binding;GO:0034618:arginine binding;GO:0008013:beta-catenin binding;GO:0045296:cadherin binding;GO:0005516:calmodulin binding;GO:0008603:cAMP-dependent protein kinase regulator activity;GO:0050660:flavin adenine dinucleotide binding;GO:0010181:FMN binding;GO:0020037:heme binding;GO:0051879:Hsp90 protein binding;GO:0042802:identical protein binding;GO:0046872:metal ion binding;GO:0050661:NADP binding;GO:0004517:nitric-oxide synthase activity;GO:0050998:nitric-oxide synthase binding;GO:0016491:oxidoreductase activity;GO:0016709:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0042803:protein homodimerization activity;GO:0019901:protein kinase binding;GO:0034617:tetrahydrobiopterin binding;	K13241	;ko00220 Arginine biosynthesis;ko00330 Arginine and proline metabolism;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko04020 Calcium signaling pathway;ko04066 HIF-1 signaling pathway;ko04146 Peroxisome;ko04371 Apelin signaling pathway;ko04926 Relaxin signaling pathway;ko05010 Alzheimer disease;ko05014 Amyotrophic lateral sclerosis;ko05022 Pathways of neurodegeneration - multiple diseases;ko05133 Pertussis;ko05140 Leishmaniasis;ko05142 Chagas disease;ko05145 Toxoplasmosis;ko05146 Amoebiasis;ko05152 Tuberculosis;ko05200 Pathways in cancer;ko05222 Small cell lung cancer;
ENSMUSG00000027358	3555	51	0.74	33	0.53	12	0.16	11	0.18	26.0927456968072	0.286676870934285	-1.8025025821277	0.593344038230959	-3.03787089106316	0.00238256009373417	0.0155729652503494	Down	2	133394079	133404805	+	Bmp2	bone morphogenetic protein 2 [Source:MGI Symbol%3BAcc:MGI:88177]	GO:0000187:activation of MAPK activity;GO:0009887:organ morphogenesis;GO:0003176:aortic valve development;	GO:0070724:BMP receptor complex;GO:0009986:cell surface;GO:0005737:cytoplasm;GO:0005576:extracellular region;	GO:0070700:BMP receptor binding;GO:0039706:co-receptor binding;GO:0005125:cytokine activity;GO:0008083:growth factor activity;	K04662	;ko04013 MAPK signaling pathway - fly;ko04060 Cytokine-cytokine receptor interaction;ko04341 Hedgehog signaling pathway - fly;ko04350 TGF-beta signaling pathway;ko04390 Hippo signaling pathway;ko04550 Signaling pathways regulating pluripotency of stem cells;ko04919 Thyroid hormone signaling pathway;ko05200 Pathways in cancer;ko05217 Basal cell carcinoma;ko05418 Fluid shear stress and atherosclerosis;
ENSMUSG00000021250	2352	5	0.11	6	0.15	23	0.45	30	0.76	16.3357443113003	5.09203845956712	2.34824331578625	0.773032085544761	3.03770485041566	0.00238387315821786	0.0155734452175073	Ups	12	85520664	85524047	+	Fos	FBJ osteosarcoma oncogene [Source:MGI Symbol%3BAcc:MGI:95574]	GO:0007568:aging;GO:0071276:cellular response to cadmium ion;GO:0071277:cellular response to calcium ion;GO:0031668:cellular response to extracellular stimulus;GO:0032870:cellular response to hormone stimulus;GO:0034614:cellular response to reactive oxygen species;GO:0001661:conditioned taste aversion;GO:0007565:female pregnancy;GO:0007399:nervous system development;GO:1901216:positive regulation of neuron death;GO:0045672:positive regulation of osteoclast differentiation;GO:1902895:positive regulation of pri-miRNA transcription from RNA polymerase II promoter;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-templated;GO:0010468:regulation of gene expression;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0006355:regulation of transcription, DNA-templated;GO:0051591:response to cAMP;GO:0009409:response to cold;GO:0051412:response to corticosterone;GO:0034097:response to cytokine;GO:0042493:response to drug;GO:0009629:response to gravity;GO:0035902:response to immobilization stress;GO:0009416:response to light stimulus;GO:0032496:response to lipopolysaccharide;GO:0035994:response to muscle stretch;GO:0032570:response to progesterone;GO:0009636:response to toxic substance;GO:0035914:skeletal muscle cell differentiation;GO:0030431:sleep;GO:0060395:SMAD protein signal transduction;GO:0006366:transcription from RNA polymerase II promoter;GO:0007179:transforming growth factor beta receptor signaling pathway;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005783:endoplasmic reticulum;GO:0016020:membrane;GO:0043005:neuron projection;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0032993:protein-DNA complex;GO:0035976:AP1 complex;GO:0005667:transcription factor complex;	GO:0003682:chromatin binding;GO:0003677:DNA binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003690:double-stranded DNA binding;GO:0042802:identical protein binding;GO:0044877:macromolecular complex binding;GO:0070412:R-SMAD binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000979:RNA polymerase II core promoter sequence-specific DNA binding;GO:0061629:RNA polymerase II sequence-specific DNA binding transcription factor binding;GO:0043565:sequence-specific DNA binding;GO:0000976:transcription regulatory region sequence-specific DNA binding;	K04379	;ko01522 Endocrine resistance;ko04010 MAPK signaling pathway;ko04024 cAMP signaling pathway;ko04210 Apoptosis;ko04380 Osteoclast differentiation;ko04620 Toll-like receptor signaling pathway;ko04657 IL-17 signaling pathway;ko04658 Th1 and Th2 cell differentiation;ko04659 Th17 cell differentiation;ko04660 T cell receptor signaling pathway;ko04662 B cell receptor signaling pathway;ko04668 TNF signaling pathway;ko04713 Circadian entrainment;ko04725 Cholinergic synapse;ko04728 Dopaminergic synapse;ko04915 Estrogen signaling pathway;ko04917 Prolactin signaling pathway;ko04921 Oxytocin signaling pathway;ko04926 Relaxin signaling pathway;ko04928 Parathyroid hormone synthesis, secretion and action;ko04932 Non-alcoholic fatty liver disease;ko04935 Growth hormone synthesis, secretion and action;ko05031 Amphetamine addiction;ko05130 Pathogenic Escherichia coli infection;ko05132 Salmonella infection;ko05133 Pertussis;ko05135 Yersinia infection;ko05140 Leishmaniasis;ko05142 Chagas disease;ko05161 Hepatitis B;ko05162 Measles;ko05166 Human T-cell leukemia virus 1 infection;ko05167 Kaposi sarcoma-associated herpesvirus infection;ko05170 Human immunodeficiency virus 1 infection;ko05171 Coronavirus disease - COVID-19;ko05200 Pathways in cancer;ko05210 Colorectal cancer;ko05224 Breast cancer;ko05231 Choline metabolism in cancer;ko05235 PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05323 Rheumatoid arthritis;ko05418 Fluid shear stress and atherosclerosis;
ENSMUSG00000116919	1420	75	2.74	83	3.33	23	0.75	36	1.51	53.7378913056289	0.395552176941017	-1.3380600829982	0.442433401241061	-3.02431977161949	0.00249192896146667	0.0162186921456409	Down	16	55703435	55704854	-	Gm17809	predicted gene%2C 17809 [Source:MGI Symbol%3BAcc:MGI:5009995]	GO:0071276:cellular response to cadmium ion;GO:0034614:cellular response to reactive oxygen species;GO:0071356:cellular response to tumor necrosis factor;GO:0098586:cellular response to virus;GO:0051607:defense response to virus;GO:0007249:I-kappaB kinase/NF-kappaB signaling;GO:0007252:I-kappaB phosphorylation;GO:0007595:lactation;GO:0060749:mammary gland alveolus development;GO:0033598:mammary gland epithelial cell proliferation;GO:0002011:morphogenesis of an epithelial sheet;GO:0032088:negative regulation of NF-kappaB transcription factor activity;GO:0038061:NIK/NF-kappaB signaling;GO:0042475:odontogenesis of dentin-containing tooth;GO:0030316:osteoclast differentiation;GO:0018105:peptidyl-serine phosphorylation;GO:0043123:positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032727:positive regulation of interferon-alpha production;GO:0051092:positive regulation of NF-kappaB transcription factor activity;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-templated;GO:0006468:protein phosphorylation;GO:0032496:response to lipopolysaccharide;GO:0035994:response to muscle stretch;GO:0010033:response to organic substance;GO:0007266:Rho protein signal transduction;GO:0051146:striated muscle cell differentiation;GO:0033209:tumor necrosis factor-mediated signaling pathway;	GO:0035631:CD40 receptor complex;GO:0005737:cytoplasm;GO:0009898:cytoplasmic side of plasma membrane;GO:0005829:cytosol;GO:0008385:IkappaB kinase complex;GO:0043231:intracellular membrane-bounded organelle;GO:0005654:nucleoplasm;	GO:0005524:ATP binding;GO:0008384:IkappaB kinase activity;GO:0046982:protein heterodimerization activity;GO:0042803:protein homodimerization activity;GO:0004672:protein kinase activity;GO:0004674:protein serine/threonine kinase activity;GO:0044877:macromolecular complex binding;GO:0097110:scaffold protein binding;GO:1990459:transferrin receptor binding;	K04467	;ko01523 Antifolate resistance;ko04010 MAPK signaling pathway;ko04014 Ras signaling pathway;ko04062 Chemokine signaling pathway;ko04064 NF-kappa B signaling pathway;ko04068 FoxO signaling pathway;ko04150 mTOR signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04210 Apoptosis;ko04380 Osteoclast differentiation;ko04620 Toll-like receptor signaling pathway;ko04621 NOD-like receptor signaling pathway;ko04622 RIG-I-like receptor signaling pathway;ko04623 Cytosolic DNA-sensing pathway;ko04625 C-type lectin receptor signaling pathway;ko04657 IL-17 signaling pathway;ko04658 Th1 and Th2 cell differentiation;ko04659 Th17 cell differentiation;ko04660 T cell receptor signaling pathway;ko04662 B cell receptor signaling pathway;ko04668 TNF signaling pathway;ko04920 Adipocytokine signaling pathway;ko05010 Alzheimer disease;ko05120 Epithelial cell signaling in Helicobacter pylori infection;ko05130 Pathogenic Escherichia coli infection;ko05131 Shigellosis;ko05132 Salmonella infection;ko05135 Yersinia infection;ko05142 Chagas disease;ko05145 Toxoplasmosis;ko05160 Hepatitis C;ko05161 Hepatitis B;ko05162 Measles;ko05163 Human cytomegalovirus infection;ko05164 Influenza A;ko05165 Human papillomavirus infection;ko05166 Human T-cell leukemia virus 1 infection;ko05167 Kaposi sarcoma-associated herpesvirus infection;ko05168 Herpes simplex virus 1 infection;ko05169 Epstein-Barr virus infection;ko05170 Human immunodeficiency virus 1 infection;ko05171 Coronavirus disease - COVID-19;ko05200 Pathways in cancer;ko05212 Pancreatic cancer;ko05215 Prostate cancer;ko05220 Chronic myeloid leukemia;ko05221 Acute myeloid leukemia;ko05222 Small cell lung cancer;ko05235 PD-L1 expression and PD-1 checkpoint pathway in cancer;ko05418 Fluid shear stress and atherosclerosis;
ENSMUSG00000117905	3709	100	1.40	147	2.26	61	0.76	53	0.85	89.0850114046783	0.478100350506927	-1.06461463152675	0.352485244353639	-3.02030978198523	0.00252516267164741	0.0164001882283106	Down	19	4218741	4241046	-	Gm50230	predicted gene%2C 50230 [Source:MGI Symbol%3BAcc:MGI:6303033]	-	-	-	-	-
ENSMUSG00000020475	840	58	3.58	39	2.64	16	0.88	14	0.99	30.9977918406742	0.323277463779627	-1.62915515663651	0.539906404888894	-3.0174769957985	0.00254888386156702	0.0165262516419741	Down	11	5751640	5753733	-	Pgam2	phosphoglycerate mutase 2 [Source:MGI Symbol%3BAcc:MGI:1933118]	GO:0006094:gluconeogenesis;GO:0006096:glycolytic process;GO:0007219:Notch signaling pathway;GO:0010035:response to inorganic substance;GO:0046689:response to mercury ion;GO:0007283:spermatogenesis;GO:0006941:striated muscle contraction;	GO:0005829:cytosol;GO:0005634:nucleus;	GO:0046538:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity;GO:0004082:bisphosphoglycerate mutase activity;GO:0016787:hydrolase activity;GO:0042802:identical protein binding;GO:0004619:phosphoglycerate mutase activity;	K01834	;ko00010 Glycolysis / Gluconeogenesis;ko00260 Glycine, serine and threonine metabolism;ko00680 Methane metabolism;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko01120 Microbial metabolism in diverse environments;ko01200 Carbon metabolism;ko01230 Biosynthesis of amino acids;ko04922 Glucagon signaling pathway;ko05230 Central carbon metabolism in cancer;
ENSMUSG00000103527	1101	40	1.89	37	1.91	1	0.04	12	0.65	22.2478030158863	0.185350308609066	-2.43167357763481	0.80751949042085	-3.01128778497656	0.00260142170942943	0.01678880492104	Down	3	51580222	51581322	+	Gm37261	predicted gene%2C 37261 [Source:MGI Symbol%3BAcc:MGI:5610489]	-	-	-	-	-
ENSMUSG00000041347	1435	13	0.47	10	0.40	42	1.35	34	1.41	24.7037813753052	3.43776254678852	1.78146989839321	0.591771941206797	3.01039940278389	0.00260904357668786	0.0168116932942566	Ups	12	105569344	105571687	+	Bdkrb1	bradykinin receptor%2C beta 1 [Source:MGI Symbol%3BAcc:MGI:88144]	GO:0016477:cell migration;GO:0007186:G-protein coupled receptor signaling pathway;GO:0006954:inflammatory response;GO:0045776:negative regulation of blood pressure;GO:0030308:negative regulation of cell growth;GO:0001933:negative regulation of protein phosphorylation;GO:0002687:positive regulation of leukocyte migration;GO:0051281:positive regulation of release of sequestered calcium ion into cytosol;GO:0007205:protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0032496:response to lipopolysaccharide;GO:0009612:response to mechanical stimulus;GO:0019233:sensory perception of pain;GO:0007204:positive regulation of cytosolic calcium ion concentration;	GO:0016021:integral component of membrane;GO:0016020:membrane;GO:0043005:neuron projection;GO:0005886:plasma membrane;GO:0005783:endoplasmic reticulum;GO:0005887:integral component of plasma membrane;	GO:0004947:bradykinin receptor activity;GO:0004930:G-protein coupled receptor activity;GO:0042277:peptide binding;	K03915	;ko04020 Calcium signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04610 Complement and coagulation cascades;ko04750 Inflammatory mediator regulation of TRP channels;ko04810 Regulation of actin cytoskeleton;ko05200 Pathways in cancer;
ENSMUSG00000107227	3532	28	0.41	14	0.23	46	0.60	74	1.25	41.3236282025118	3.07109167170163	1.61875157722275	0.537815288665894	3.00986530382621	0.00261363569529041	0.0168322090514839	Ups	5	34627008	34630539	+	Gm42559	predicted gene 42559 [Source:MGI Symbol%3BAcc:MGI:5662696]	-	-	-	-	-
ENSMUSG00000002083	2124	58	1.42	75	2.01	192	4.16	90	2.52	101.641870696574	2.14622683907618	1.10180256552375	0.366202612729334	3.00872393375879	0.00262347383526867	0.0168884751427413	Ups	7	16042318	16052130	+	Bbc3	BCL2 binding component 3 [Source:MGI Symbol%3BAcc:MGI:2181667]	GO:0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006915:apoptotic process;GO:0097190:apoptotic signaling pathway;GO:0006974:cellular response to DNA damage stimulus;GO:0071456:cellular response to hypoxia;GO:0071479:cellular response to ionizing radiation;GO:0008340:determination of adult lifespan;GO:0097194:execution phase of apoptosis;GO:0072332:intrinsic apoptotic signaling pathway by p53 class mediator;GO:0042771:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0070059:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0030308:negative regulation of cell growth;GO:0032471:negative regulation of endoplasmic reticulum calcium ion concentration;GO:0045926:negative regulation of growth;GO:0043065:positive regulation of apoptotic process;GO:2001056:positive regulation of cysteine-type endopeptidase activity;GO:2001244:positive regulation of intrinsic apoptotic signaling pathway;GO:0043525:positive regulation of neuron apoptotic process;GO:0032464:positive regulation of protein homooligomerization;GO:1900740:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0031334:positive regulation of protein complex assembly;GO:0090200:positive regulation of release of cytochrome c from mitochondria;GO:0070245:positive regulation of thymocyte apoptotic process;GO:0001836:release of cytochrome c from mitochondria;GO:0051209:release of sequestered calcium ion into cytosol;GO:0034976:response to endoplasmic reticulum stress;GO:1901998:toxin transport;	GO:0005783:endoplasmic reticulum;GO:0005740:mitochondrial envelope;GO:0005739:mitochondrion;	GO:0051117:ATPase binding;	K10132	;ko01524 Platinum drug resistance;ko04115 p53 signaling pathway;ko04210 Apoptosis;ko04215 Apoptosis - multiple species;ko04390 Hippo signaling pathway;ko05016 Huntington disease;ko05162 Measles;ko05200 Pathways in cancer;ko05210 Colorectal cancer;
ENSMUSG00000019539	1717	86	2.60	140	4.64	60	1.61	38	1.32	79.6194925769738	0.443645274382946	-1.17252149360143	0.389883224850983	-3.00736584409237	0.00263522410943015	0.0169262406735756	Down	7	44732337	44741645	-	Rcn3	reticulocalbin 3%2C EF-hand calcium binding domain [Source:MGI Symbol%3BAcc:MGI:1277122]	GO:0032964:collagen biosynthetic process;GO:0036503:ERAD pathway;GO:0060428:lung epithelium development;GO:0055091:phospholipid homeostasis;GO:0010952:positive regulation of peptidase activity;GO:0009306:protein secretion;GO:0015031:protein transport;GO:0051896:regulation of protein kinase B signaling;GO:0043129:surfactant homeostasis;	GO:0005783:endoplasmic reticulum;GO:0005788:endoplasmic reticulum lumen;GO:0043231:intracellular membrane-bounded organelle;	GO:0005509:calcium ion binding;	-	-
ENSMUSG00000100215	396	1	0.13	4	0.57	29	3.37	13	1.96	11.5271488898093	8.46204291861983	3.08100600291513	1.02457539446386	3.00710520627655	0.00263748465838209	0.0169289199462666	Ups	1	55374560	55374955	+	Gm8292	predicted gene 8292 [Source:MGI Symbol%3BAcc:MGI:3648460]	GO:0002181:cytoplasmic translation;GO:0034101:erythrocyte homeostasis;GO:0042274:ribosomal small subunit biogenesis;GO:0006364:rRNA processing;GO:0006412:translation;	GO:0005829:cytosol;GO:0022626:cytosolic ribosome;GO:0022627:cytosolic small ribosomal subunit;GO:0005783:endoplasmic reticulum;GO:0016020:membrane;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0015935:small ribosomal subunit;	GO:0003723:RNA binding;GO:0003735:structural constituent of ribosome;GO:0031369:translation initiation factor binding;	K02974	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000065601	65	2	1.60	0	0.00	17	12.03	15	13.74	8.56517637833737	16.7962759608508	4.07006949167855	1.35715079541779	2.99898103101033	0.00270884171270373	0.0173322778612118	Ups	11	43265224	43265288	-	Mir146	microRNA 146 [Source:MGI Symbol%3BAcc:MGI:2676831]	-	-	-	-	-
ENSMUSG00000044566	4523	89	1.02	89	1.12	32	0.33	42	0.55	62.2803312611331	0.438455927446976	-1.18949626122351	0.396708890416292	-2.99841090018248	0.00271391498415209	0.017350745040854	Down	13	38190028	38221045	-	Cage1	cancer antigen 1 [Source:MGI Symbol%3BAcc:MGI:1918463]	-	-	-	K13238	;ko00071 Fatty acid degradation;
ENSMUSG00000049897	2191	18	0.43	23	0.60	2	0.04	3	0.08	11.2826702912149	0.12771212065647	-2.9690326428211	0.990658573640037	-2.99702917011237	0.00272624625331807	0.0173894592547335	Down	2	26824059	26843508	+	Stkld1	serine/threonine kinase-like domain containing 1 [Source:MGI Symbol%3BAcc:MGI:2685557]	-	-	GO:0005524:ATP binding;GO:0004674:protein serine/threonine kinase activity;	K17546	-
ENSMUSG00000106455	421	51	6.29	54	7.30	21	2.30	15	2.12	34.5186194593383	0.354450840801048	-1.49634254260007	0.49959332594519	-2.99512116133479	0.00274335846103469	0.0174761119592496	Down	3	121173908	121174328	-	Gm5711	predicted gene 5711 [Source:MGI Symbol%3BAcc:MGI:3643596]	GO:0000187:activation of MAPK activity;GO:0032148:activation of protein kinase B activity;GO:0006915:apoptotic process;GO:0060352:cell adhesion molecule production;GO:0034599:cellular response to oxidative stress;GO:0042118:endothelial cell activation;GO:0030595:leukocyte chemotaxis;GO:0034389:lipid particle organization;GO:1902176:negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0032515:negative regulation of phosphoprotein phosphatase activity;GO:0006469:negative regulation of protein kinase activity;GO:0001933:negative regulation of protein phosphorylation;GO:0032873:negative regulation of stress-activated MAPK cascade;GO:1903901:negative regulation of viral life cycle;GO:0030182:neuron differentiation;GO:0030593:neutrophil chemotaxis;GO:0030168:platelet activation;GO:0070527:platelet aggregation;GO:0051092:positive regulation of NF-kappaB transcription factor activity;GO:0035307:positive regulation of protein dephosphorylation;GO:0001934:positive regulation of protein phosphorylation;GO:0050714:positive regulation of protein secretion;GO:0045070:positive regulation of viral genome replication;GO:0006457:protein folding;GO:0000413:protein peptidyl-prolyl isomerization;GO:2001233:regulation of apoptotic signaling pathway;GO:0045069:regulation of viral genome replication;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005576:extracellular region;GO:0043231:intracellular membrane-bounded organelle;GO:0005634:nucleus;GO:0032991:macromolecular complex;	GO:0016018:cyclosporin A binding;GO:0005178:integrin binding;GO:0003755:peptidyl-prolyl cis-trans isomerase activity;	K03767	;ko01503 Cationic antimicrobial peptide (CAMP) resistance;ko04217 Necroptosis;
ENSMUSG00000108101	233	11	2.45	11	2.69	43	8.49	31	7.92	23.8741234829148	3.47651697546988	1.79764263407665	0.601801378025238	2.98710288762626	0.00281634921632947	0.01785278994758	Ups	6	48022482	48022889	-	Gm45738	predicted gene 45738 [Source:MGI Symbol%3BAcc:MGI:5804853]	-	-	-	-	-
ENSMUSG00000022528	2037	7	0.18	8	0.22	33	0.75	27	0.79	18.7674003098865	4.15069045311615	2.05335134379258	0.687824325116572	2.98528456876628	0.00283314622637001	0.0179116002125453	Ups	16	29883202	29886614	+	Hes1	hes family bHLH transcription factor 1 [Source:MGI Symbol%3BAcc:MGI:104853]	GO:0009952:anterior/posterior pattern specification;GO:0033504:floor plate development;GO:0002088:lens development in camera-type eye;GO:0007517:muscle organ development;GO:0043066:negative regulation of apoptotic process;GO:0048642:negative regulation of skeletal muscle tissue development;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0045892:negative regulation of transcription, DNA-templated;GO:0014029:neural crest formation;GO:0007219:Notch signaling pathway;GO:0021501:prechordal plate formation;GO:0050767:regulation of neurogenesis;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0021984:adenohypophysis development;GO:0048844:artery morphogenesis;GO:0035910:ascending aorta morphogenesis;	GO:0005634:nucleus;GO:0005737:cytoplasm;GO:0005654:nucleoplasm;GO:0032991:macromolecular complex;	GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046982:protein heterodimerization activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043565:sequence-specific DNA binding;GO:0051087:chaperone binding;GO:0003677:DNA binding;GO:0001227:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;	K06054	;ko03460 Fanconi anemia pathway;ko04330 Notch signaling pathway;ko04950 Maturity onset diabetes of the young;ko05165 Human papillomavirus infection;ko05169 Epstein-Barr virus infection;ko05200 Pathways in cancer;ko05224 Breast cancer;
ENSMUSG00000070720	1476	1	0.04	0	0.00	25	0.78	9	0.36	8.49314939897913	34.2874170390703	5.09960732125828	1.70829307646689	2.98520633930412	0.00283387093164036	0.0179116002125453	Ups	4	131648511	131650451	+	Tmem200b	transmembrane protein 200B [Source:MGI Symbol%3BAcc:MGI:3646343]	-	GO:0016021:integral component of membrane;	-	-	-
ENSMUSG00000025418	2756	27	0.51	22	0.45	3	0.05	5	0.11	13.9438437749166	0.172576504329065	-2.53469203474662	0.849088735658602	-2.98519097981034	0.00283401323942052	0.0179116002125453	Down	4	106340653	106349480	-	Bsnd	barttin CLCNK type accessory beta subunit [Source:MGI Symbol%3BAcc:MGI:2153465]	GO:0030644:cellular chloride ion homeostasis;GO:0006873:cellular ion homeostasis;GO:0030007:cellular potassium ion homeostasis;GO:0006821:chloride transport;GO:0007605:sensory perception of sound;	GO:0016323:basolateral plasma membrane;GO:0016021:integral component of membrane;GO:0005887:integral component of plasma membrane;GO:0032991:macromolecular complex;	GO:0017081:chloride channel regulator activity;	K19331	-
ENSMUSG00000075576	1823	67	1.91	94	2.93	27	0.68	35	1.14	55.2365187712397	0.404412329772736	-1.30610111191247	0.437674167932226	-2.98418597122854	0.00284333897357176	0.0179349073717603	Down	11	98688533	98700913	-	Gm12359	predicted gene 12359 [Source:MGI Symbol%3BAcc:MGI:3702436]	-	-	-	-	-
ENSMUSG00000112264	2031	34	0.87	32	0.90	10	0.23	6	0.18	19.978413482062	0.250023300356385	-1.99986554503117	0.670197223861369	-2.9839955670196	0.00284510893725432	0.0179386926167178	Down	10	96331583	96359844	-	Gm48505	predicted gene%2C 48505 [Source:MGI Symbol%3BAcc:MGI:6098035]	-	-	-	-	-
ENSMUSG00000032607	2437	70	1.49	124	2.90	47	0.89	32	0.78	67.1903166680892	0.417311473808851	-1.26080350742872	0.423251240746479	-2.97885365960196	0.00289328924372443	0.0181659728849735	Down	9	108174052	108179501	+	Amt	aminomethyltransferase [Source:MGI Symbol%3BAcc:MGI:3646700]	GO:0019464:glycine decarboxylation via glycine cleavage system;	GO:0005739:mitochondrion;GO:0005654:nucleoplasm;	GO:0004047:aminomethyltransferase activity;GO:0008483:transaminase activity;	K00605	;ko00260 Glycine, serine and threonine metabolism;ko00630 Glyoxylate and dicarboxylate metabolism;ko00670 One carbon pool by folate;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko01200 Carbon metabolism;
ENSMUSG00000032875	10795	8	0.04	7	0.04	40	0.17	22	0.12	18.9668098568717	4.23184357168554	2.08128629982327	0.698708978649233	2.97875991782284	0.00289417448741051	0.0181659728849735	Ups	7	100518959	100581314	-	Arhgef17	Rho guanine nucleotide exchange factor (GEF) 17 [Source:MGI Symbol%3BAcc:MGI:2673002]	GO:0030036:actin cytoskeleton organization;	-	GO:0005085:guanyl-nucleotide exchange factor activity;	-	-
ENSMUSG00000037759	5193	11	0.11	11	0.12	38	0.34	35	0.40	23.8415070679558	3.46246667386969	1.79180018533531	0.601551150930329	2.97863312631718	0.00289537222713415	0.0181659728849735	Ups	14	45225652	45241277	+	Ptger2	prostaglandin E receptor 2 (subtype EP2) [Source:MGI Symbol%3BAcc:MGI:97794]	GO:0007189:adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0071380:cellular response to prostaglandin E stimulus;GO:0006954:inflammatory response;GO:0007204:positive regulation of cytosolic calcium ion concentration;GO:0042127:regulation of cell proliferation;GO:0032496:response to lipopolysaccharide;GO:0032570:response to progesterone;	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0004957:prostaglandin E receptor activity;	K04259	;ko04024 cAMP signaling pathway;ko04080 Neuroactive ligand-receptor interaction;ko04750 Inflammatory mediator regulation of TRP channels;ko04924 Renin secretion;ko05163 Human cytomegalovirus infection;ko05200 Pathways in cancer;
ENSMUSG00000112280	7840	37	0.25	45	0.33	7	0.04	14	0.11	25.4739416910785	0.271919019727762	-1.87875102882352	0.631063045168743	-2.9771209757991	0.00290969171836206	0.0182259856247401	Down	10	33863212	33871051	-	A830082N09Rik	RIKEN cDNA A830082N09 gene [Source:MGI Symbol%3BAcc:MGI:3041184]	-	-	-	-	-
ENSMUSG00000019066	4196	75	0.93	82	1.11	25	0.27	36	0.51	53.9479376041767	0.410499520778588	-1.2845475571005	0.432110738701511	-2.97272768772318	0.00295166195806455	0.0184105969993533	Down	9	21818787	21829488	-	Rab3d	RAB3D%2C member RAS oncogene family [Source:MGI Symbol%3BAcc:MGI:97844]	GO:0045453:bone resorption;GO:0018125:peptidyl-cysteine methylation;GO:1903307:positive regulation of regulated secretory pathway;GO:0072659:protein localization to plasma membrane;GO:0009306:protein secretion;GO:0017157:regulation of exocytosis;GO:0006904:vesicle docking involved in exocytosis;	GO:0005881:cytoplasmic microtubule;GO:0005768:endosome;GO:0005739:mitochondrion;GO:0005886:plasma membrane;GO:0008021:synaptic vesicle;GO:0030133:transport vesicle;GO:0042588:zymogen granule;	GO:0005525:GTP binding;GO:0030742:GTP-dependent protein binding;GO:0003924:GTPase activity;GO:0031489:myosin V binding;	K07884	;ko04972 Pancreatic secretion;
ENSMUSG00000074491	2462	9	0.19	6	0.14	23	0.43	39	0.94	19.7911705245199	4.43365396320384	2.14849617547112	0.723238508518928	2.97066064674969	0.00297159941682009	0.0185154430952943	Ups	8	3757064	3770651	-	Clec4g	C-type lectin domain family 4%2C member g [Source:MGI Symbol%3BAcc:MGI:1923113]	GO:0002710:negative regulation of T cell mediated immunity;GO:0042130:negative regulation of T cell proliferation;GO:1903902:positive regulation of viral life cycle;GO:0046718:viral entry into host cell;	GO:0005887:integral component of plasma membrane;GO:0005886:plasma membrane;	GO:0097367:carbohydrate derivative binding;GO:0070061:fructose binding;GO:0005537:mannose binding;GO:0030247:polysaccharide binding;GO:0001618:virus receptor activity;	K10061	-
ENSMUSG00000077734	94	25	13.81	15	9.08	61	29.86	46	29.14	36.4977113297796	2.78164827601167	1.47594001063024	0.497301984447364	2.96789487431948	0.00299846863065247	0.0186223240107027	Ups	15	79962699	79962792	-	Snord83b	small nucleolar RNA%2C C/D box 83B [Source:MGI Symbol%3BAcc:MGI:3819557]	-	-	-	-	-
ENSMUSG00000121028	685	20	1.52	13	1.08	1	0.07	1	0.09	8.47057852602707	0.0634201532396573	-3.97891482640067	1.34077840338995	-2.96761554059984	0.00300119461715479	0.0186317077973488	Down	8	85798084	85798768	-	-	novel transcript%2C antisense to Dhps	-	-	-	-	-
ENSMUSG00000024891	3018	88	1.51	53	1.00	182	2.77	101	1.99	103.99899348477	2.06242778364314	1.0443436039626	0.351975095669259	2.9670951633008	0.00300627895074361	0.0186406313913071	Ups	19	5073888	5082000	+	Slc29a2	solute carrier family 29 (nucleoside transporters)%2C member 2 [Source:MGI Symbol%3BAcc:MGI:1345278]	GO:0015853:adenine transport;GO:0032238:adenosine transport;GO:0015854:guanine transport;GO:0035344:hypoxanthine transport;GO:0098810:neurotransmitter uptake involved in synaptic transmission;GO:0006836:neurotransmitter transport;GO:0001504:neurotransmitter uptake;GO:1901642:nucleoside transmembrane transport;GO:0015858:nucleoside transport;GO:0015860:purine nucleoside transmembrane transport;GO:0072531:pyrimidine-containing compound transmembrane transport;GO:0035364:thymine transport;GO:0015862:uridine transport;	GO:0016323:basolateral plasma membrane;GO:0016021:integral component of membrane;GO:0005887:integral component of plasma membrane;GO:0031965:nuclear membrane;GO:0005886:plasma membrane;GO:0098793:presynapse;	GO:0005326:neurotransmitter transporter activity;GO:0005337:nucleoside transmembrane transporter activity;GO:0015211:purine nucleoside transmembrane transporter activity;GO:0015213:uridine transmembrane transporter activity;	K15014	;ko05034 Alcoholism;
ENSMUSG00000104043	1029	4	0.20	4	0.22	34	1.52	14	0.81	13.6628912693917	6.07056979817194	2.60183193763684	0.877295442645367	2.96574199655177	0.00301953683629357	0.0187077082213033	Ups	3	84081411	84082439	+	Gm6525	predicted pseudogene 6525 [Source:MGI Symbol%3BAcc:MGI:3648757]	GO:0006412:translation;	GO:0022625:cytosolic large ribosomal subunit;	GO:0003735:structural constituent of ribosome;	K02929	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000038764	7238	75	0.54	68	0.53	112	0.71	165	1.36	106.452761829109	2.06387035846808	1.04535235105705	0.353036528045704	2.96103170072452	0.00306610378466889	0.0189655649189644	Ups	4	57190841	57301837	-	Ptpn3	protein tyrosine phosphatase%2C non-receptor type 3 [Source:MGI Symbol%3BAcc:MGI:105307]	GO:0097421:liver regeneration;GO:0051045:negative regulation of membrane protein ectodomain proteolysis;GO:0045930:negative regulation of mitotic cell cycle;GO:0006470:protein dephosphorylation;GO:0098902:regulation of membrane depolarization during action potential;GO:2000649:regulation of sodium ion transmembrane transporter activity;	GO:0005737:cytoplasm;GO:0009898:cytoplasmic side of plasma membrane;GO:0005856:cytoskeleton;	GO:0051117:ATPase binding;GO:0008092:cytoskeletal protein binding;GO:0001784:phosphotyrosine binding;GO:0004725:protein tyrosine phosphatase activity;GO:0017080:sodium channel regulator activity;	K18027	-
ENSMUSG00000017697	2002	86	2.23	80	2.27	226	5.19	103	3.06	120.935809039262	2.0111513979385	1.00802169071019	0.340996269798459	2.95610767620997	0.00311548305193153	0.0192167405946573	Ups	2	163568504	163592159	-	Ada	adenosine deaminase [Source:MGI Symbol%3BAcc:MGI:87916]	GO:0006154:adenosine catabolic process;GO:0046085:adenosine metabolic process;GO:0007568:aging;GO:0000255:allantoin metabolic process;GO:0006196:AMP catabolic process;GO:0007155:cell adhesion;GO:0046059:dAMP catabolic process;GO:0046061:dATP catabolic process;GO:0006157:deoxyadenosine catabolic process;GO:0048566:embryonic digestive tract development;GO:0002314:germinal center B cell differentiation;GO:0001821:histamine secretion;GO:0046101:hypoxanthine biosynthetic process;GO:0043103:hypoxanthine salvage;GO:0001701:in utero embryonic development;GO:0046103:inosine biosynthetic process;GO:0001889:liver development;GO:0048286:lung alveolus development;GO:0030324:lung development;GO:0060169:negative regulation of adenosine receptor signaling pathway;GO:0043066:negative regulation of apoptotic process;GO:0042323:negative regulation of circadian sleep/wake cycle, non-REM sleep;GO:0050728:negative regulation of inflammatory response;GO:0002686:negative regulation of leukocyte migration;GO:0002906:negative regulation of mature B cell apoptotic process;GO:0070256:negative regulation of mucus secretion;GO:0060407:negative regulation of penile erection;GO:0070244:negative regulation of thymocyte apoptotic process;GO:0048541:Peyer's patch development;GO:0001890:placenta development;GO:0046638:positive regulation of alpha-beta T cell differentiation;GO:0030890:positive regulation of B cell proliferation;GO:0050850:positive regulation of calcium-mediated signaling;GO:0002636:positive regulation of germinal center formation;GO:0010460:positive regulation of heart rate;GO:0045987:positive regulation of smooth muscle contraction;GO:0050870:positive regulation of T cell activation;GO:0045582:positive regulation of T cell differentiation;GO:0033089:positive regulation of T cell differentiation in thymus;GO:0050862:positive regulation of T cell receptor signaling pathway;GO:0032261:purine nucleotide salvage;GO:0009168:purine ribonucleoside monophosphate biosynthetic process;GO:0033632:regulation of cell-cell adhesion mediated by integrin;GO:0045580:regulation of T cell differentiation;GO:0042493:response to drug;GO:0042542:response to hydrogen peroxide;GO:0001666:response to hypoxia;GO:0043278:response to morphine;GO:0033197:response to vitamin E;GO:0042110:T cell activation;GO:0001829:trophectodermal cell differentiation;GO:0046111:xanthine biosynthetic process;	GO:0030054:cell junction;GO:0009986:cell surface;GO:0005737:cytoplasm;GO:0060205:cytoplasmic membrane-bounded vesicle lumen;GO:0005829:cytosol;GO:0032839:dendrite cytoplasm;GO:0009897:external side of plasma membrane;GO:0005615:extracellular space;GO:0005764:lysosome;GO:0016020:membrane;GO:0043025:neuronal cell body;GO:0005886:plasma membrane;	GO:0046936:deoxyadenosine deaminase activity;GO:0004000:adenosine deaminase activity;GO:0001883:purine nucleoside binding;GO:0008270:zinc ion binding;	K01488	;ko00230 Purine metabolism;ko01100 Metabolic pathways;ko05340 Primary immunodeficiency;
ENSMUSG00000045092	3046	143	2.44	264	4.93	91	1.37	100	1.96	148.439992750674	0.489353138592722	-1.03105214213549	0.34916643692083	-2.95289590611273	0.00314808099038379	0.0193866160267249	Down	3	115504082	115508721	-	S1pr1	sphingosine-1-phosphate receptor 1 [Source:MGI Symbol%3BAcc:MGI:1096355]	GO:0031532:actin cytoskeleton reorganization;GO:0007189:adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007193:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0001525:angiogenesis;GO:0001955:blood vessel maturation;GO:0007420:brain development;GO:0003245:cardiac muscle tissue growth involved in heart morphogenesis;GO:0016477:cell migration;GO:0006935:chemotaxis;GO:0045446:endothelial cell differentiation;GO:0007186:G-protein coupled receptor signaling pathway;GO:0061384:heart trabecula morphogenesis;GO:0030032:lamellipodium assembly;GO:0030595:leukocyte chemotaxis;GO:0051497:negative regulation of stress fiber assembly;GO:0030182:neuron differentiation;GO:0030335:positive regulation of cell migration;GO:0008284:positive regulation of cell proliferation;GO:0051482:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0043547:positive regulation of GTPase activity;GO:0050927:positive regulation of positive chemotaxis;GO:0048661:positive regulation of smooth muscle cell proliferation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0030500:regulation of bone mineralization;GO:0045124:regulation of bone resorption;GO:0030155:regulation of cell adhesion;GO:0019222:regulation of metabolic process;GO:0003376:sphingosine-1-phosphate signaling pathway;GO:0072678:T cell migration;GO:0019226:transmission of nerve impulse;	GO:0005901:caveola;GO:0005737:cytoplasm;GO:0005768:endosome;GO:0009897:external side of plasma membrane;GO:0016021:integral component of membrane;GO:0043231:intracellular membrane-bounded organelle;GO:0031226:intrinsic component of plasma membrane;GO:0005654:nucleoplasm;GO:0005886:plasma membrane;	GO:0004930:G-protein coupled receptor activity;GO:0001664:G-protein coupled receptor binding;GO:0046625:sphingolipid binding;GO:0038036:sphingosine-1-phosphate receptor activity;	K04288	;ko04068 FoxO signaling pathway;ko04071 Sphingolipid signaling pathway;ko04080 Neuroactive ligand-receptor interaction;
ENSMUSG00000043993	2534	0	0.00	1	0.02	24	0.44	9	0.21	8.27705741333998	33.1742870358064	5.05199355517886	1.71099748518168	2.95265983669312	0.003150489205841	0.0193936577608855	Ups	11	120117214	120122464	-	2900052L18Rik	RIKEN cDNA 2900052L18 gene [Source:MGI Symbol%3BAcc:MGI:1924085]	-	-	-	-	-
ENSMUSG00000118106	2276	27	0.62	18	0.45	65	1.31	49	1.28	39.4747378103167	2.63207751718657	1.39620197844011	0.472992411520491	2.95184858030143	0.00315877788436121	0.0194290814596048	Ups	19	32463323	32465598	+	-	TEC	-	-	-	-	-
ENSMUSG00000120095	1763	38	1.12	51	1.65	82	2.14	109	3.68	70.9586654622529	2.26679483601716	1.18065382096182	0.400524989250442	2.94776568915547	0.00320079569373806	0.0196402565697397	Ups	8	85391725	85396050	+	-	novel transcript	-	-	-	-	-
ENSMUSG00000085175	1503	43	1.49	51	1.93	103	3.15	85	3.37	70.2653450698206	2.07440675996866	1.05269881269093	0.357592688965158	2.94384881228235	0.00324158309639588	0.0198428883034469	Ups	11	82670423	82671925	-	Gm11423	predicted gene 11423 [Source:MGI Symbol%3BAcc:MGI:3651335]	-	-	-	-	-
ENSMUSG00000092591	3696	12	0.17	30	0.46	3	0.04	2	0.03	11.5652678605042	0.121866050307682	-3.03663182187801	1.03248976414152	-2.94107692622294	0.0032707329673521	0.0199179584278701	Down	17	37557802	37574944	+	Gm20429	predicted gene 20429 [Source:MGI Symbol%3BAcc:MGI:5141894]	-	-	-	-	-
ENSMUSG00000023912	3935	54	0.71	47	0.68	22	0.26	12	0.18	32.8716302672703	0.346166094236859	-1.53046367021696	0.520512120300894	-2.94030361739173	0.00327890777912896	0.0199554901729677	Down	17	43952782	43978105	-	Slc25a27	solute carrier family 25%2C member 27 [Source:MGI Symbol%3BAcc:MGI:1921261]	GO:0035356:cellular triglyceride homeostasis;GO:0048839:inner ear development;GO:0043066:negative regulation of apoptotic process;GO:0051562:negative regulation of mitochondrial calcium ion concentration;GO:0010917:negative regulation of mitochondrial membrane potential;GO:0070997:neuron death;GO:0008284:positive regulation of cell proliferation;GO:0046324:regulation of glucose import;GO:0009409:response to cold;	GO:0045177:apical part of cell;GO:0016021:integral component of membrane;GO:0005743:mitochondrial inner membrane;GO:0031966:mitochondrial membrane;GO:0005739:mitochondrion;GO:0043025:neuronal cell body;	-	K15112	-
ENSMUSG00000032387	2506	1	0.02	0	0.00	19	0.35	12	0.29	7.95161047158605	31.9320454516146	4.99693306459414	1.70000346180007	2.93936640535019	0.00328884019297765	0.0199964613477872	Ups	9	65536930	65567810	+	Rbpms2	RNA binding protein with multiple splicing 2 [Source:MGI Symbol%3BAcc:MGI:1919223]	GO:0048557:embryonic digestive tract morphogenesis;GO:0030514:negative regulation of BMP signaling pathway;GO:0051151:negative regulation of smooth muscle cell differentiation;GO:0048661:positive regulation of smooth muscle cell proliferation;	GO:0005737:cytoplasm;	GO:0042802:identical protein binding;GO:0003729:mRNA binding;GO:0042803:protein homodimerization activity;	-	-
ENSMUSG00000056458	3405	51	0.78	23	0.38	141	1.91	55	0.96	65.5235681410781	2.69087660461127	1.4280762349036	0.486383252702325	2.93611308976876	0.00332353134031142	0.0201753877958572	Ups	12	110774232	110807373	-	Mok	MOK protein kinase [Source:MGI Symbol%3BAcc:MGI:1336881]	GO:0035556:intracellular signal transduction;	GO:0097546:ciliary base;GO:0005929:cilium;GO:0005737:cytoplasm;GO:0005634:nucleus;	GO:0005524:ATP binding;GO:0004693:cyclin-dependent protein serine/threonine kinase activity;GO:0046872:metal ion binding;GO:0004674:protein serine/threonine kinase activity;	K08830	-
ENSMUSG00000081665	3462	30	0.45	30	0.49	5	0.07	8	0.14	17.9449909145014	0.228737952724231	-2.12823233401616	0.725231574315869	-2.93455553975814	0.00334025768507517	0.0202368673816447	Down	7	3734629	3742888	-	Pira1	paired-Ig-like receptor A1 [Source:MGI Symbol%3BAcc:MGI:1195971]	GO:0001782:B cell homeostasis;GO:0019724:B cell mediated immunity;GO:0019221:cytokine-mediated signaling pathway;GO:0007611:learning or memory;GO:0043011:myeloid dendritic cell differentiation;GO:0051248:negative regulation of protein metabolic process;GO:1900454:positive regulation of long term synaptic depression;GO:0035307:positive regulation of protein dephosphorylation;GO:1900271:regulation of long-term synaptic potentiation;	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0001540:beta-amyloid binding;GO:0042803:protein homodimerization activity;GO:0044877:macromolecular complex binding;	K06512	;ko04380 Osteoclast differentiation;ko04662 B cell receptor signaling pathway;
ENSMUSG00000097080	3682	121	1.71	92	1.42	51	0.64	49	0.79	76.8967034099817	0.491723683957672	-1.0240802503951	0.349429018904016	-2.93072468224628	0.00338172345372439	0.0204481821347125	Down	18	38371429	38383689	-	1700086O06Rik	RIKEN cDNA 1700086O06 gene [Source:MGI Symbol%3BAcc:MGI:1920766]	-	-	-	-	-
ENSMUSG00000091312	63	1	0.82	0	0.00	5	3.65	28	26.47	9.20001578821405	36.7728582166458	5.20056941107293	1.77709454737666	2.92644497657708	0.00342860149652782	0.0206903484249341	Ups	2	11630417	11631075	-	Gm17490	predicted gene%2C 17490 [Source:MGI Symbol%3BAcc:MGI:4937124]	-	-	-	-	-
ENSMUSG00000086443	1638	14	0.44	6	0.21	52	1.46	24	0.87	23.4483409145843	3.88524066876631	1.95800396822926	0.669928010831901	2.92270801723585	0.00347001747453318	0.0208827503746043	Ups	4	122855102	122857268	+	4933421A08Rik	RIKEN cDNA 4933421A08 gene [Source:MGI Symbol%3BAcc:MGI:1918347]	-	-	-	-	-
ENSMUSG00000085274	847	24	1.47	21	1.41	0	0.00	5	0.35	12.2972583769055	0.121113798440244	-3.04556485489827	1.04321216021927	-2.9194108073454	0.00350693734556708	0.0210671397747577	Down	2	165699604	165700954	+	BC046401	cDNA sequence BC046401 [Source:MGI Symbol%3BAcc:MGI:2683561]	-	-	-	-	-
ENSMUSG00000027329	2747	72	1.36	76	1.57	32	0.54	30	0.65	51.6769196007636	0.436623575477623	-1.19553806417755	0.40982671286251	-2.91717944842368	0.00353212497656913	0.0211734184482842	Down	2	131012181	131029202	-	Spef1	sperm flagellar 1 [Source:MGI Symbol%3BAcc:MGI:3513546]	GO:1904158:axonemal central apparatus assembly;GO:0016477:cell migration;GO:0003341:cilium movement;GO:0046847:filopodium assembly;GO:0030032:lamellipodium assembly;GO:0001578:microtubule bundle formation;GO:0060548:negative regulation of cell death;GO:0007026:negative regulation of microtubule depolymerization;GO:0051493:regulation of cytoskeleton organization;GO:2000095:regulation of Wnt signaling pathway, planar cell polarity pathway;	GO:0016324:apical plasma membrane;GO:1990716:axonemal central apparatus;GO:0005930:axoneme;GO:0016323:basolateral plasma membrane;GO:0097542:ciliary tip;GO:0005737:cytoplasm;GO:0030175:filopodium;GO:0030027:lamellipodium;GO:0005874:microtubule;GO:0005902:microvillus;GO:0031514:motile cilium;	GO:0003779:actin binding;GO:0008017:microtubule binding;	K05866	;ko04010 MAPK signaling pathway;ko04110 Cell cycle;ko04914 Progesterone-mediated oocyte maturation;ko05206 MicroRNAs in cancer;
ENSMUSG00000087538	377	36	4.96	72	10.87	19	2.32	15	2.37	35.0135255379092	0.323937201642298	-1.6262139350503	0.557979333809747	-2.91446983160991	0.0035629324339503	0.0212982415296044	Down	1	86203231	86229097	-	Gm16341	predicted gene 16341 [Source:MGI Symbol%3BAcc:MGI:3840137]	-	-	-	-	-
ENSMUSG00000031129	5679	34	0.31	40	0.40	9	0.07	11	0.12	23.1407739499563	0.283192099221297	-1.8201470786658	0.624771860068839	-2.91329874950714	0.00357632274943356	0.0213548804672174	Down	9	94551962	95112498	+	Slc9a9	solute carrier family 9 (sodium/hydrogen exchanger)%2C member 9 [Source:MGI Symbol%3BAcc:MGI:2679732]	GO:0071805:potassium ion transmembrane transport;GO:0051453:regulation of intracellular pH;GO:0098719:sodium ion import across plasma membrane;	GO:0016021:integral component of membrane;GO:0031902:late endosome membrane;GO:0005886:plasma membrane;GO:0055037:recycling endosome;	GO:0015386:potassium:proton antiporter activity;GO:0015385:sodium:proton antiporter activity;	K14725	-
ENSMUSG00000085433	3156	113	1.86	123	2.22	48	0.70	62	1.17	85.6857448375158	0.491266482533749	-1.02542228269009	0.352226863198738	-2.91125518757356	0.00359979880497454	0.0214616309780247	Down	5	124242612	124250327	-	Gm16001	predicted gene 16001 [Source:MGI Symbol%3BAcc:MGI:3802119]	-	-	-	-	-
ENSMUSG00000004110	25228	964	1.98	1146	2.59	246	0.45	425	1.00	688.538051101197	0.340940827989824	-1.55240672095511	0.533604267683378	-2.90928467962752	0.0036225682826754	0.0215387600025376	Down	1	154266477	154760247	-	Cacna1e	calcium channel%2C voltage-dependent%2C R type%2C alpha 1E subunit [Source:MGI Symbol%3BAcc:MGI:106217]	GO:0001662:behavioral fear response;GO:0048266:behavioral response to pain;GO:0070509:calcium ion import;GO:0070588:calcium ion transmembrane transport;GO:0006816:calcium ion transport;GO:0007268:synaptic transmission;GO:0042596:fear response;GO:0030317:sperm motility;GO:0042593:glucose homeostasis;GO:0007626:locomotory behavior;GO:0050877:neurological system process;GO:0002027:regulation of heart rate;GO:0061178:regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0034765:regulation of ion transmembrane transport;GO:0090273:regulation of somatostatin secretion;GO:0048265:response to pain;GO:0019233:sensory perception of pain;GO:0019226:transmission of nerve impulse;GO:0008542:visual learning;	GO:0043204:perikaryon;GO:0005891:voltage-gated calcium channel complex;GO:0005886:plasma membrane;GO:0045202:synapse;	GO:0005509:calcium ion binding;GO:0047485:protein N-terminus binding;GO:0005245:voltage-gated calcium channel activity;GO:0022843:voltage-gated cation channel activity;	K04852	;ko04010 MAPK signaling pathway;ko04020 Calcium signaling pathway;ko04930 Type II diabetes mellitus;
ENSMUSG00000071414	948	9	0.49	8	0.48	33	1.60	29	1.82	19.7973367089375	3.8021119188367	1.9268009997335	0.662832603855494	2.90691946733744	0.00365007154453702	0.0216686786929658	Ups	12	13505024	13505971	-	Gm6736	predicted gene 6736 [Source:MGI Symbol%3BAcc:MGI:3643048]	GO:0071475:cellular hyperosmotic salinity response;GO:0070301:cellular response to hydrogen peroxide;GO:0097238:cellular response to methylglyoxal;GO:1901653:cellular response to peptide;GO:0044597:daunorubicin metabolic process;GO:0044598:doxorubicin metabolic process;GO:0002070:epithelial cell maturation;GO:0072061:inner medullary collecting duct development;GO:0060135:maternal process involved in female pregnancy;GO:0072205:metanephric collecting duct development;GO:0005996:monosaccharide metabolic process;GO:0043066:negative regulation of apoptotic process;GO:0042415:norepinephrine metabolic process;GO:1901360:organic cyclic compound metabolic process;GO:0046427:positive regulation of JAK-STAT cascade;GO:0048661:positive regulation of smooth muscle cell proliferation;GO:0035809:regulation of urine volume;GO:0003091:renal water homeostasis;GO:0010033:response to organic substance;GO:0097066:response to thyroid hormone;GO:0009414:response to water deprivation;GO:0001523:retinoid metabolic process;GO:0006061:sorbitol biosynthetic process;GO:0031098:stress-activated protein kinase signaling cascade;GO:0001894:tissue homeostasis;	GO:0005829:cytosol;GO:0005615:extracellular space;GO:0042629:mast cell granule;GO:0005654:nucleoplasm;GO:0033010:paranodal junction;GO:0048471:perinuclear region of cytoplasm;GO:0032838:cell projection cytoplasm;GO:0043220:Schmidt-Lanterman incisure;GO:0097454:Schwann cell microvillus;	GO:0004032:alditol:NADP+ 1-oxidoreductase activity;GO:0047655:allyl-alcohol dehydrogenase activity;GO:0018505:cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity;GO:0047834:D-threo-aldose 1-dehydrogenase activity;GO:0043795:glyceraldehyde oxidoreductase activity;GO:0047956:glycerol dehydrogenase [NADP+] activity;GO:0052650:NADP-retinol dehydrogenase activity;GO:0036130:prostaglandin H2 endoperoxidase reductase activity;GO:0001758:retinal dehydrogenase activity;	K00011	;ko00040 Pentose and glucuronate interconversions;ko00051 Fructose and mannose metabolism;ko00052 Galactose metabolism;ko00561 Glycerolipid metabolism;ko00790 Folate biosynthesis;ko01100 Metabolic pathways;
ENSMUSG00000045349	3740	25	0.35	27	0.41	67	0.82	55	0.88	43.3835067767359	2.43534314042464	1.28412506270236	0.442149168677851	2.90428016984008	0.00368098599465223	0.0218099842511582	Ups	4	137977714	137988643	+	Sh2d5	SH2 domain containing 5 [Source:MGI Symbol%3BAcc:MGI:2446215]	-	GO:0014069:postsynaptic density;	-	-	-
ENSMUSG00000030217	2517	21	0.43	18	0.41	65	1.19	39	0.92	35.2684858810697	2.74029420091619	1.45433079078351	0.501434857309534	2.90033843795138	0.00372759945167608	0.0220350848080189	Ups	6	136825449	136834731	-	Art4	ADP-ribosyltransferase 4 [Source:MGI Symbol%3BAcc:MGI:1202710]	GO:0018120:peptidyl-arginine ADP-ribosylation;	GO:0031225:anchored component of membrane;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0003950:NAD+ ADP-ribosyltransferase activity;	K06717	-
ENSMUSG00000022197	18419	75	0.21	61	0.19	15	0.04	31	0.10	45.0131413292115	0.362729292539502	-1.46303483870228	0.504830354712584	-2.89807224356632	0.00375464092264153	0.0221607636288627	Down	15	12359797	12740010	-	Pdzd2	PDZ domain containing 2 [Source:MGI Symbol%3BAcc:MGI:1922394]	GO:0007155:cell adhesion;GO:0035556:intracellular signal transduction;	GO:0045177:apical part of cell;GO:0005911:cell-cell junction;GO:0005737:cytoplasm;GO:0005783:endoplasmic reticulum;GO:0005576:extracellular region;GO:0043005:neuron projection;GO:0005634:nucleus;GO:0014069:postsynaptic density;	-	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000078532	1426	8	0.29	1	0.04	27	0.87	23	0.96	14.7609025959168	5.84634043473994	2.54753384029878	0.879476472388093	2.89664808585648	0.00377172585877472	0.0222530374445754	Ups	4	130297197	130339644	+	Nkain1	Na+/K+ transporting ATPase interacting 1 [Source:MGI Symbol%3BAcc:MGI:1914399]	GO:0002028:regulation of sodium ion transport;	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0051117:ATPase binding;	-	-
ENSMUSG00000042377	6659	41	0.32	58	0.50	102	0.70	96	0.86	74.3810772425788	2.08161979033656	1.05770658319673	0.365578470225887	2.89324090268003	0.00381288728602105	0.0224010780244624	Ups	11	61574917	61600777	+	Fam83g	family with sequence similarity 83%2C member G [Source:MGI Symbol%3BAcc:MGI:1916890]	GO:0030509:BMP signaling pathway;GO:0007165:signal transduction;	GO:0005829:cytosol;GO:0005634:nucleus;	GO:0019901:protein kinase binding;	K14390	-
ENSMUSG00000071324	7188	28	0.20	43	0.34	8	0.05	10	0.08	21.9654384193307	0.265010626558305	-1.91587788398288	0.662367306382211	-2.89247048506549	0.00382225092992931	0.0224474897585354	Down	10	41790986	41894438	-	Armc2	armadillo repeat containing 2 [Source:MGI Symbol%3BAcc:MGI:1916449]	GO:0044782:cilium organization;GO:0007288:sperm axoneme assembly;	-	-	-	-
ENSMUSG00000103898	2603	25	0.50	37	0.81	84	1.48	59	1.35	50.9025242115445	2.37220766994066	1.24623031312128	0.431338195682362	2.88921854265603	0.00386200565280973	0.022611681817558	Ups	12	112657420	112660022	-	Gm30238	predicted gene%2C 30238 [Source:MGI Symbol%3BAcc:MGI:5589397]	-	-	-	-	-
ENSMUSG00000035513	3990	42	0.55	40	0.57	16	0.18	9	0.13	26.078095521799	0.313611172042536	-1.6729511401432	0.580242499602695	-2.8831930465085	0.00393666105550118	0.0229785917872307	Down	2	29084553	29143017	-	Ntng2	netrin G2 [Source:MGI Symbol%3BAcc:MGI:2159341]	GO:0009887:organ morphogenesis;GO:0007409:axonogenesis;GO:0070831:basement membrane assembly;GO:0016477:cell migration;GO:0050804:regulation of synaptic transmission;GO:2001222:regulation of neuron migration;GO:0010975:regulation of neuron projection development;GO:0034446:substrate adhesion-dependent cell spreading;GO:0009888:tissue development;	GO:0046658:anchored component of plasma membrane;GO:0030424:axon;GO:0090543:Flemming body;GO:0045171:intercellular bridge;GO:0043256:laminin complex;GO:0005886:plasma membrane;GO:0005576:extracellular region;	-	K16359	;ko04360 Axon guidance;ko04514 Cell adhesion molecules;
ENSMUSG00000026814	4048	6	0.08	10	0.14	34	0.39	27	0.40	19.260509343342	3.94013872200214	1.97824642410333	0.686704801033962	2.88078140872863	0.00396690653091252	0.0231199333884502	Ups	2	32536607	32572681	+	Eng	endoglin [Source:MGI Symbol%3BAcc:MGI:95392]	GO:0001525:angiogenesis;GO:0048844:artery morphogenesis;GO:0055009:atrial cardiac muscle tissue morphogenesis;	GO:0009986:cell surface;GO:0072563:endothelial microparticle;GO:0009897:external side of plasma membrane;GO:0005615:extracellular space;	GO:0036122:BMP binding;GO:0015026:coreceptor activity;GO:0005534:galactose binding;GO:0005539:glycosaminoglycan binding;	K06526	-
ENSMUSG00000113895	1201	0	0.00	1	0.05	11	0.42	18	0.89	7.80149977821383	30.9070429582186	4.94986372535047	1.71982187593902	2.87812580744611	0.00400045565076145	0.0232671824956664	Ups	12	100431298	100454649	+	Gm48383	predicted gene%2C 48383 [Source:MGI Symbol%3BAcc:MGI:6097863]	-	-	-	-	-
ENSMUSG00000103261	4485	42	0.49	25	0.32	72	0.74	77	1.02	54.1834240102929	2.34626042462685	1.23036315508238	0.427658587837131	2.87697520890414	0.00401507137778916	0.0233385536417813	Ups	3	83966275	83970759	-	Gm36981	predicted gene%2C 36981 [Source:MGI Symbol%3BAcc:MGI:5610209]	-	-	-	-	-
ENSMUSG00000024177	1582	17	0.56	24	0.86	61	1.77	45	1.69	36.5779367572012	2.66616760249214	1.41476747498203	0.493006853498377	2.8696710095262	0.00410899074806209	0.0237583952227693	Ups	17	26310708	26314576	-	Nme4	NME/NM23 nucleoside diphosphate kinase 4 [Source:MGI Symbol%3BAcc:MGI:1931148]	GO:0006241:CTP biosynthetic process;GO:0006183:GTP biosynthetic process;GO:0006869:lipid transport;GO:0006228:UTP biosynthetic process;	GO:0016020:membrane;GO:0005758:mitochondrial intermembrane space;GO:0005759:mitochondrial matrix;GO:0005739:mitochondrion;	GO:0005524:ATP binding;GO:1901612:cardiolipin binding;GO:0051020:GTPase binding;GO:0046872:metal ion binding;GO:0004550:nucleoside diphosphate kinase activity;GO:0044877:macromolecular complex binding;	K00940	;ko00230 Purine metabolism;ko00240 Pyrimidine metabolism;ko00983 Drug metabolism - other enzymes;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko01240 Biosynthesis of cofactors;ko04016 MAPK signaling pathway - plant;
ENSMUSG00000101320	977	11	0.58	16	0.93	39	1.84	42	2.56	27.2729804798982	3.14014523538934	1.65083128699282	0.57609834047122	2.86553730677738	0.00416302217295713	0.0240255107264301	Ups	18	6490143	6496962	+	Gm28529	predicted gene 28529 [Source:MGI Symbol%3BAcc:MGI:5579235]	-	-	-	-	-
ENSMUSG00000073412	415	20	2.50	28	3.84	80	8.87	43	6.17	42.0920221405552	2.60954249901472	1.38379689788428	0.483897495028715	2.85969014533162	0.00424055115463376	0.0243994789512773	Ups	17	35404071	35407415	-	Lst1	leukocyte specific transcript 1 [Source:MGI Symbol%3BAcc:MGI:1096324]	GO:0000902:cell morphogenesis;GO:0016358:dendrite development;GO:0006955:immune response;GO:0050672:negative regulation of lymphocyte proliferation;GO:0008360:regulation of cell shape;	GO:0005737:cytoplasm;GO:0016021:integral component of membrane;	-	-	-
ENSMUSG00000114095	659	50	3.94	22	1.90	2	0.14	11	0.99	20.8134189231917	0.198322981486104	-2.3340762294489	0.817434288540266	-2.85536863595113	0.00429869017978749	0.0246692047967295	Down	13	64008896	64010105	+	Gm47424	predicted gene%2C 47424 [Source:MGI Symbol%3BAcc:MGI:6096366]	-	-	-	-	-
ENSMUSG00000071723	3781	2	0.03	2	0.03	18	0.22	15	0.24	9.29414292829479	8.57646103953647	3.10038246194947	1.08843440251779	2.84847892971557	0.00439287620811236	0.0251250890619899	Ups	X	93679675	93686850	+	Gspt2	G1 to S phase transition 2 [Source:MGI Symbol%3BAcc:MGI:1316727]	GO:0007049:cell cycle;GO:0002184:cytoplasmic translational termination;GO:0000184:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006412:translation;	GO:0005829:cytosol;GO:0018444:translation release factor complex;	GO:0005525:GTP binding;GO:0003924:GTPase activity;GO:0003747:translation release factor activity;	K03267	;ko03015 mRNA surveillance pathway;
ENSMUSG00000085516	927	113	6.33	76	4.67	28	1.39	47	3.02	65.1727120711006	0.424559324292958	-1.23596193714347	0.434113546410381	-2.84709368634877	0.00441203759025845	0.0251783343539349	Down	11	24110528	24122824	-	4930538E20Rik	RIKEN cDNA 4930538E20 gene [Source:MGI Symbol%3BAcc:MGI:1925450]	-	-	-	-	-
ENSMUSG00000034209	1413	9	0.33	5	0.20	32	1.04	24	1.01	17.423239383589	4.15824875455404	2.05597606561017	0.722298682503011	2.84643474426052	0.00442117896862008	0.0252211154407814	Ups	11	5008128	5010385	+	Rasl10a	RAS-like%2C family 10%2C member A [Source:MGI Symbol%3BAcc:MGI:1922918]	GO:0007165:signal transduction;	GO:0005730:nucleolus;GO:0005886:plasma membrane;	GO:0005525:GTP binding;	K07850	-
ENSMUSG00000016493	7603	115	0.79	149	1.12	48	0.29	72	0.56	95.4375780678634	0.481090601299293	-1.05561948002626	0.371261385162559	-2.84333227805002	0.00446444998408713	0.0254018092972141	Down	1	194719134	194774557	-	Cd46	CD46 antigen%2C complement regulatory protein [Source:MGI Symbol%3BAcc:MGI:1203290]	GO:0045959:negative regulation of complement activation, classical pathway;GO:0010629:negative regulation of gene expression;GO:0010628:positive regulation of gene expression;GO:0032733:positive regulation of interleukin-10 production;GO:0043382:positive regulation of memory T cell differentiation;GO:0045862:positive regulation of proteolysis;GO:0045591:positive regulation of regulatory T cell differentiation;GO:0042102:positive regulation of T cell proliferation;GO:0071636:positive regulation of transforming growth factor beta production;GO:0006508:proteolysis;GO:0008593:regulation of Notch signaling pathway;GO:0035581:sequestering of extracellular ligand from receptor;GO:0007338:single fertilization;GO:0002456:T cell mediated immunity;	GO:0001669:acrosomal vesicle;GO:0016323:basolateral plasma membrane;GO:0009986:cell surface;GO:0005737:cytoplasm;GO:0005576:extracellular region;GO:0005794:Golgi apparatus;GO:0002079:inner acrosomal membrane;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0045296:cadherin binding;	K04007	;ko04610 Complement and coagulation cascades;ko05162 Measles;
ENSMUSG00000020256	7503	28	0.19	44	0.33	5	0.03	12	0.10	22.0838016574193	0.251098915098013	-1.99367229959574	0.703997443709114	-2.8319311631187	0.004626780808907	0.0261990609024298	Down	10	83323314	83370004	-	Aldh1l2	aldehyde dehydrogenase 1 family%2C member L2 [Source:MGI Symbol%3BAcc:MGI:2444680]	GO:0009258:10-formyltetrahydrofolate catabolic process;GO:0009058:biosynthetic process;GO:0006730:one-carbon metabolic process;	GO:0005739:mitochondrion;GO:0005654:nucleoplasm;GO:0070062:extracellular exosome;GO:0005759:mitochondrial matrix;	GO:0004029:aldehyde dehydrogenase (NAD) activity;GO:0016155:formyltetrahydrofolate dehydrogenase activity;GO:0016742:hydroxymethyl-, formyl- and related transferase activity;	K00289	;ko00670 One carbon pool by folate;
ENSMUSG00000078635	747	2	0.14	2	0.15	25	1.54	10	0.80	9.5072723190514	8.84376676712224	3.14466097807668	1.11089134157992	2.83075478255533	0.0046438308944591	0.0262665079069111	Ups	11	103155686	103158571	-	1700028N14Rik	RIKEN cDNA 1700028N14 gene [Source:MGI Symbol%3BAcc:MGI:1920530]	-	-	-	-	-
ENSMUSG00000113601	1310	55	2.18	46	2.00	10	0.35	21	0.95	32.6121646177833	0.328536643194986	-1.60587380498681	0.567560792290417	-2.8294304800482	0.00466309297065311	0.0263468824845044	Down	13	62829006	62830315	-	Gm48735	predicted gene%2C 48735 [Source:MGI Symbol%3BAcc:MGI:6098399]	-	-	-	-	-
ENSMUSG00002076700	127	2	0.82	9	4.03	28	10.15	25	11.72	16.1304095745501	4.97397948579513	2.31440055745376	0.818636680928858	2.82714006270492	0.00469657807571838	0.0264964415794944	Ups	10	94657391	94657517	-	5S_rRNA	5S ribosomal RNA [Source:RFAM%3BAcc:RF00001]	-	-	-	-	-
ENSMUSG00000090516	475	42	4.59	38	4.55	100	9.69	65	8.15	60.5133327210619	2.1250432361005	1.08749219460244	0.384816707825378	2.82600046330609	0.00471331958757195	0.0265615738904183	Ups	9	59379042	59379516	-	Rps11-ps1	ribosomal protein S11%2C pseudogene 1 [Source:MGI Symbol%3BAcc:MGI:3644744]	GO:0006412:translation;	GO:0005840:ribosome;	GO:0019843:rRNA binding;GO:0003735:structural constituent of ribosome;	K02949	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000095200	388	81	10.84	64	9.39	35	4.15	27	4.14	50.6568123651614	0.444428605851361	-1.16997641544275	0.414675432891626	-2.82142688628606	0.0047810534448174	0.0268544591658718	Down	12	114502115	114502585	-	Ighv1-7	immunoglobulin heavy variable V1-7 [Source:MGI Symbol%3BAcc:MGI:3704122]	-	-	-	-	-
ENSMUSG00000026837	8559	0	0.00	1	0.01	20	0.11	9	0.06	7.35781009569752	29.3437494510649	4.8749813206652	1.73077570714254	2.81664533454404	0.00485280814601236	0.0271778524875652	Ups	2	27776437	27929526	+	Col5a1	collagen%2C type V%2C alpha 1 [Source:MGI Symbol%3BAcc:MGI:88457]	GO:0001568:blood vessel development;GO:0007155:cell adhesion;GO:0016477:cell migration;GO:0032964:collagen biosynthetic process;GO:0030199:collagen fibril organization;GO:0030198:extracellular matrix organization;GO:0048592:eye morphogenesis;GO:0003007:heart morphogenesis;GO:0045112:integrin biosynthetic process;GO:1903225:negative regulation of endodermal cell differentiation;GO:0051128:regulation of cellular component organization;GO:0043588:skin development;GO:0097435:fibril organization;GO:0035989:tendon development;GO:0035313:wound healing, spreading of epidermal cells;	GO:0005604:basement membrane;GO:0005581:collagen trimer;GO:0005588:collagen type V trimer;GO:0031012:extracellular matrix;GO:0005615:extracellular space;	GO:0005201:extracellular matrix structural constituent;GO:0008201:heparin binding;GO:0048407:platelet-derived growth factor binding;GO:0043394:proteoglycan binding;	K19721	;ko04974 Protein digestion and absorption;
ENSMUSG00000043740	5256	43	0.42	54	0.58	22	0.19	11	0.12	31.7451284246393	0.347406732076603	-1.52530238390346	0.541798145029951	-2.81525951665844	0.00487378586650633	0.0272654624140854	Down	17	48623169	48634052	+	B430306N03Rik	RIKEN cDNA B430306N03 gene [Source:MGI Symbol%3BAcc:MGI:2443478]	-	-	-	K14364	-
ENSMUSG00000035105	2662	5	0.10	29	0.62	53	0.92	64	1.43	38.4601417027072	3.58199320186395	1.84076259928745	0.654763981864265	2.8113375968641	0.00493359899940415	0.0275297696713476	Ups	12	54225767	54250646	-	Egln3	egl-9 family hypoxia-inducible factor 3 [Source:MGI Symbol%3BAcc:MGI:1932288]	GO:0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006915:apoptotic process;GO:0006974:cellular response to DNA damage stimulus;GO:0071456:cellular response to hypoxia;GO:0018401:peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0018126:protein hydroxylation;GO:0042127:regulation of cell proliferation;GO:0043523:regulation of neuron apoptotic process;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005634:nucleus;	GO:0016706:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0008198:ferrous iron binding;GO:0031418:L-ascorbic acid binding;GO:0031545:peptidyl-proline 4-dioxygenase activity;GO:0031543:peptidyl-proline dioxygenase activity;	K09592	;ko04066 HIF-1 signaling pathway;ko05200 Pathways in cancer;ko05211 Renal cell carcinoma;
ENSMUSG00000117286	13507	49	0.19	33	0.14	10	0.03	14	0.06	25.9987390540527	0.31006172590665	-1.68937264456592	0.601038624196019	-2.81075554308297	0.00494253224865332	0.0275595598184909	Down	5	37242714	37386891	+	Gm1043	predicted gene 1043 [Source:MGI Symbol%3BAcc:MGI:2685889]	GO:0050890:cognition;GO:0015031:protein transport;GO:0021756:striatum development;	GO:0005737:cytoplasm;GO:0019898:extrinsic component of membrane;GO:0005874:microtubule;GO:0015630:microtubule cytoskeleton;	GO:0050811:GABA receptor binding;GO:0019900:kinase binding;GO:0019894:kinesin binding;GO:0008017:microtubule binding;GO:0003723:RNA binding;	-	-
ENSMUSG00000023963	3053	55	0.94	101	1.88	28	0.42	32	0.62	53.5457498754703	0.401142529027963	-1.31781316646836	0.469004078585633	-2.80981174074747	0.00495704864195331	0.0276304557890629	Down	17	43978316	44062322	+	Cyp39a1	cytochrome P450%2C family 39%2C subfamily a%2C polypeptide 1 [Source:MGI Symbol%3BAcc:MGI:1927096]	GO:0006699:bile acid biosynthetic process;GO:0030573:bile acid catabolic process;GO:0006707:cholesterol catabolic process;GO:0042632:cholesterol homeostasis;GO:0007586:digestion;	GO:0005789:endoplasmic reticulum membrane;GO:0016021:integral component of membrane;GO:0043231:intracellular membrane-bounded organelle;	GO:0020037:heme binding;GO:0005506:iron ion binding;GO:0008396:oxysterol 7-alpha-hydroxylase activity;GO:0008387:steroid 7-alpha-hydroxylase activity;GO:0008395:steroid hydroxylase activity;	K07439	;ko00120 Primary bile acid biosynthesis;
ENSMUSG00000021676	6910	46	0.35	30	0.25	70	0.47	93	0.80	60.380888147223	2.28159657371519	1.19004372039382	0.424800174665508	2.80142003550463	0.00508782485688916	0.0282056060576784	Ups	13	95763682	96028991	-	Iqgap2	IQ motif containing GTPase activating protein 2 [Source:MGI Symbol%3BAcc:MGI:2449975]	GO:0034314:Arp2/3 complex-mediated actin nucleation;GO:0032956:regulation of actin cytoskeleton organization;GO:2000249:regulation of actin cytoskeleton reorganization;GO:0043087:regulation of GTPase activity;GO:0070493:thrombin receptor signaling pathway;	GO:0009986:cell surface;GO:0005737:cytoplasm;GO:0030175:filopodium;GO:0030027:lamellipodium;GO:0005874:microtubule;GO:0005902:microvillus;	GO:0051015:actin filament binding;GO:0071933:Arp2/3 complex binding;GO:0005516:calmodulin binding;GO:0005096:GTPase activator activity;GO:0005547:phosphatidylinositol-3,4,5-trisphosphate binding;GO:0031267:small GTPase binding;	K05767	;ko04810 Regulation of actin cytoskeleton;
ENSMUSG00000060579	1491	27	0.94	25	0.95	8	0.25	3	0.12	15.2834136367428	0.21606992999244	-2.21042978562066	0.789610732399954	-2.79939176979301	0.00511989769759368	0.0283629014793719	Down	14	11307738	12919681	+	Fhit	fragile histidine triad gene [Source:MGI Symbol%3BAcc:MGI:1277947]	GO:0015964:diadenosine triphosphate catabolic process;GO:0006260:DNA replication;GO:0072332:intrinsic apoptotic signaling pathway by p53 class mediator;GO:0032435:negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0006163:purine nucleotide metabolic process;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0001650:fibrillar center;GO:0005634:nucleus;GO:0005886:plasma membrane;	GO:0047710:bis(5'-adenosyl)-triphosphatase activity;GO:0042802:identical protein binding;GO:0016151:nickel cation binding;GO:0000166:nucleotide binding;GO:0031625:ubiquitin protein ligase binding;	K01522	;ko00230 Purine metabolism;ko01100 Metabolic pathways;ko05222 Small cell lung cancer;ko05223 Non-small cell lung cancer;
ENSMUSG00000120700	896	2	0.12	13	0.83	26	1.34	41	2.73	21.1348662851991	4.70735640762965	2.23491708779539	0.798868799997966	2.79760216921862	0.00514834816660697	0.0284896321857637	Ups	4	8939232	8943541	+	-	novel transcript	-	-	-	-	-
ENSMUSG00000032392	3886	57	0.76	67	0.98	20	0.24	27	0.41	42.2977866087759	0.39909759618698	-1.32518650553847	0.47383145990039	-2.79674656008923	0.00516200077083931	0.0285260152650551	Down	9	65102635	65146506	+	Parp16	poly (ADP-ribose) polymerase family%2C member 16 [Source:MGI Symbol%3BAcc:MGI:2446133]	GO:0030968:endoplasmic reticulum unfolded protein response;GO:0036498:IRE1-mediated unfolded protein response;GO:0060548:negative regulation of cell death;GO:0071902:positive regulation of protein serine/threonine kinase activity;GO:0006471:protein ADP-ribosylation;GO:0070213:protein auto-ADP-ribosylation;	GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0071782:endoplasmic reticulum tubular network;GO:0016021:integral component of membrane;GO:0005635:nuclear envelope;	GO:0019900:kinase binding;GO:0003950:NAD+ ADP-ribosyltransferase activity;GO:1990404:protein ADP-ribosylase activity;GO:0043539:protein serine/threonine kinase activator activity;	K00774	-
ENSMUSG00000119991	608	16	1.37	16	1.50	1	0.08	2	0.20	8.55499122386306	0.0987216940886819	-3.34048903807133	1.19447908432152	-2.79660739306186	0.00516422449300854	0.0285260152650551	Down	19	46488490	46489097	+	-	novel transcript	-	-	-	-	-
ENSMUSG00002076962	84	22	13.60	18	12.19	5	2.74	0	0.00	10.8303169950169	0.125191404006624	-2.99779258870918	1.07232419113784	-2.79560287223235	0.00518030122321738	0.0285839290956514	Down	1	173471077	173471160	-	-	-	-	-	-	-	-
ENSMUSG00000073902	7293	5143	36.61	4869	37.99	1093	6.90	2043	16.68	3249.61482950353	0.33822553676667	-1.5639425044009	0.559598918220388	-2.79475612528787	0.00519388799313253	0.028638287841314	Down	7	106195950	106203242	-	Gvin3	GTPase%2C very large interferon inducible%2C family member 3 [Source:MGI Symbol%3BAcc:MGI:3584360]	-	GO:0005829:cytosol;GO:0005634:nucleus;	GO:0005525:GTP binding;	-	-
ENSMUSG00000118264	1258	89	3.67	69	3.12	238	8.71	90	4.26	118.027333699381	2.09484662746077	1.06684462201455	0.381898643775519	2.79352817665841	0.00521364867442837	0.0287059564717001	Ups	18	64421206	64424891	+	Rps15-ps3	ribosomal protein S15%2C pseudogene 3 [Source:MGI Symbol%3BAcc:MGI:3645421]	GO:0002181:cytoplasmic translation;GO:0097421:liver regeneration;GO:0001649:osteoblast differentiation;GO:1901798:positive regulation of signal transduction by p53 class mediator;GO:0000028:ribosomal small subunit assembly;GO:0042274:ribosomal small subunit biogenesis;GO:0000056:ribosomal small subunit export from nucleus;GO:0006364:rRNA processing;GO:0006412:translation;	GO:0005829:cytosol;GO:0022626:cytosolic ribosome;GO:0022627:cytosolic small ribosomal subunit;GO:0005925:focal adhesion;GO:0016020:membrane;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0045202:synapse;	GO:0003677:DNA binding;GO:0097371:MDM2/MDM4 family protein binding;GO:0003723:RNA binding;GO:0003735:structural constituent of ribosome;	K02958	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000108214	1829	0	0.00	4	0.12	17	0.43	18	0.59	9.92910283549771	9.08107641601179	3.18286331601844	1.1404512769389	2.79088057541714	0.0052564863210829	0.0288589191720319	Ups	6	134050317	134052145	+	Gm43982	predicted gene%2C 43982 [Source:MGI Symbol%3BAcc:MGI:5690374]	-	-	-	-	-
ENSMUSG00000012350	5576	14	0.13	4	0.04	28	0.23	39	0.42	21.6203625335359	3.98976061898484	1.99630218901312	0.717164412426678	2.78360464409856	0.00537585179488761	0.0293461414819532	Ups	2	103093778	103133623	-	Ehf	ets homologous factor [Source:MGI Symbol%3BAcc:MGI:1270840]	GO:0030154:cell differentiation;GO:0030855:epithelial cell differentiation;GO:0050673:epithelial cell proliferation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-templated;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0006366:transcription from RNA polymerase II promoter;	GO:0005794:Golgi apparatus;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0003677:DNA binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K17102	-
ENSMUSG00000111740	6181	53	0.45	46	0.42	7	0.05	21	0.20	31.4510140965476	0.305672064293089	-1.70994338612804	0.614942165139134	-2.7806572439884	0.00542489803526748	0.0295297786555881	Down	10	92553370	92559550	-	Gm49783	predicted gene%2C 49783 [Source:MGI Symbol%3BAcc:MGI:6215303]	-	-	-	-	-
ENSMUSG00000116305	4545	0	0.00	1	0.01	19	0.19	9	0.12	7.12799826628691	28.3851636292737	4.82706515309206	1.73699699164878	2.77897151019826	0.00545313075812132	0.0296518819308625	Ups	15	85537757	85591728	+	Lncppara	long noncoding RNA near Ppara [Source:MGI Symbol%3BAcc:MGI:5568843]	-	-	-	-	-
ENSMUSG00000026712	6371	22	0.18	40	0.36	8	0.06	7	0.07	18.9642291904283	0.249984823090408	-2.00008758526739	0.7197663408817	-2.77880121876402	0.00545599016789432	0.0296569135889725	Down	2	14234203	14336868	+	Mrc1	mannose receptor%2C C type 1 [Source:MGI Symbol%3BAcc:MGI:97142]	GO:0071346:cellular response to interferon-gamma;GO:0071353:cellular response to interleukin-4;GO:0071222:cellular response to lipopolysaccharide;GO:0006898:receptor-mediated endocytosis;	GO:0009986:cell surface;GO:0010008:endosome membrane;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0038024:cargo receptor activity;GO:0005537:mannose binding;GO:0038023:signaling receptor activity;GO:0004888:transmembrane signaling receptor activity;	K06560	;ko04145 Phagosome;ko05152 Tuberculosis;
ENSMUSG00000033209	12315	65	0.27	85	0.39	38	0.14	27	0.13	52.8136521551037	0.446591927696884	-1.16297092070173	0.419290495612311	-2.7736639224397	0.00554289073805331	0.0300228493738288	Down	5	111027669	111437646	+	Ttc28	tetratricopeptide repeat domain 28 [Source:MGI Symbol%3BAcc:MGI:2140873]	GO:0007049:cell cycle;GO:0051301:cell division;GO:0007346:regulation of mitotic cell cycle;	GO:0005813:centrosome;GO:0005737:cytoplasm;GO:0030496:midbody;GO:0072686:mitotic spindle;GO:1990023:mitotic spindle midzone;GO:0097431:mitotic spindle pole;	GO:0019900:kinase binding;	-	-
ENSMUSG00000023805	8342	381	2.37	1676	11.43	134	0.74	150	1.07	580.814757200009	0.142967082769801	-2.80624508069086	1.01201621072082	-2.77292502922662	0.00555549179989186	0.0300698592515149	Down	17	5991555	6094565	+	Synj2	synaptojanin 2 [Source:MGI Symbol%3BAcc:MGI:1201671]	GO:0007420:brain development;GO:0046855:inositol phosphate dephosphorylation;GO:0048312:intracellular distribution of mitochondria;GO:0046856:phosphatidylinositol dephosphorylation;GO:0048488:synaptic vesicle endocytosis;	GO:0043679:axon terminus;GO:0005737:cytoplasm;GO:0005881:cytoplasmic microtubule;GO:0031315:extrinsic component of mitochondrial outer membrane;GO:0045121:membrane raft;GO:0048471:perinuclear region of cytoplasm;GO:0098793:presynapse;GO:0032587:ruffle membrane;	GO:0004445:inositol-polyphosphate 5-phosphatase activity;GO:0030165:PDZ domain binding;GO:0052744:phosphatidylinositol monophosphate phosphatase activity;GO:0004439:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0003723:RNA binding;GO:0017124:SH3 domain binding;	K01099	;ko00562 Inositol phosphate metabolism;ko01100 Metabolic pathways;ko04070 Phosphatidylinositol signaling system;
ENSMUSG00000038048	3931	3	0.04	6	0.09	22	0.26	22	0.33	13.4013319846975	5.09551950544227	2.34922924152702	0.847900042592007	2.77064408953853	0.00559455410956678	0.0302385945421562	Ups	17	58076565	58717350	+	Cntnap5c	contactin associated protein-like 5C [Source:MGI Symbol%3BAcc:MGI:3646013]	GO:0007155:cell adhesion;	GO:0016021:integral component of membrane;	GO:0004190:aspartic-type endopeptidase activity;	-	-
ENSMUSG00000117269	481	31	3.35	23	2.72	1	0.10	8	0.99	15.5145595914471	0.181795535819819	-2.45961132181125	0.887961795106932	-2.76995174270426	0.00560645984846584	0.0302815975048873	Down	17	46717930	46718410	-	Gm9706	predicted gene 9706 [Source:MGI Symbol%3BAcc:MGI:3780113]	GO:0042742:defense response to bacterium;GO:0051607:defense response to virus;GO:0007229:integrin-mediated signaling pathway;GO:0032020:ISG15-protein conjugation;GO:0019941:modification-dependent protein catabolic process;GO:0031397:negative regulation of protein ubiquitination;GO:0060339:negative regulation of type I interferon-mediated signaling pathway;GO:0045071:negative regulation of viral genome replication;GO:0030501:positive regulation of bone mineralization;GO:0045648:positive regulation of erythrocyte differentiation;GO:0032728:positive regulation of interferon-beta production;GO:0032729:positive regulation of interferon-gamma production;GO:0032733:positive regulation of interleukin-10 production;GO:0032461:positive regulation of protein oligomerization;GO:0070585:protein localization to mitochondrion;GO:0032649:regulation of interferon-gamma production;GO:0009617:response to bacterium;GO:0034340:response to type I interferon;GO:0009615:response to virus;	GO:0005737:cytoplasm;GO:0022627:cytosolic small ribosomal subunit;GO:0005576:extracellular region;GO:0005634:nucleus;	GO:0005178:integrin binding;GO:0031386:protein tag;GO:0031625:ubiquitin protein ligase binding;	K12159	;ko04622 RIG-I-like receptor signaling pathway;ko05165 Human papillomavirus infection;ko05169 Epstein-Barr virus infection;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000030703	2186	27	0.64	35	0.91	8	0.17	8	0.22	19.1747406545945	0.268615604075912	-1.89638498048293	0.684699105689521	-2.76966183353371	0.00561145197270236	0.030287224410214	Down	7	126365506	126374821	+	Gdpd3	glycerophosphodiester phosphodiesterase domain containing 3 [Source:MGI Symbol%3BAcc:MGI:1915866]	GO:0046475:glycerophospholipid catabolic process;GO:0070291:N-acylethanolamine metabolic process;GO:0034638:phosphatidylcholine catabolic process;GO:0006644:phospholipid metabolic process;	GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0016021:integral component of membrane;GO:0048471:perinuclear region of cytoplasm;	GO:0004622:lysophospholipase activity;GO:0046872:metal ion binding;GO:0008081:phosphoric diester hydrolase activity;	-	-
ENSMUSG00000020297	4157	19	0.24	28	0.38	4	0.04	5	0.07	13.7842596339521	0.199956105148617	-2.32224476406105	0.841245177486394	-2.76048508355177	0.00577155935646819	0.0309877770210376	Down	11	31950463	32009202	+	Nsg2	neuron specific gene family member 2 [Source:MGI Symbol%3BAcc:MGI:1202070]	GO:0048268:clathrin coat assembly;GO:0007212:dopamine receptor signaling pathway;GO:0016197:endosomal transport;	GO:0030659:cytoplasmic vesicle membrane;GO:0030425:dendrite;GO:0005769:early endosome;GO:0031901:early endosome membrane;GO:0005768:endosome;GO:0005794:Golgi apparatus;GO:1990674:Golgi cis cisterna membrane;GO:0016021:integral component of membrane;GO:0005770:late endosome;GO:0043202:lysosomal lumen;GO:0032585:multivesicular body membrane;GO:0032588:trans-Golgi network membrane;	GO:0032051:clathrin light chain binding;	-	-
ENSMUSG00000078490	9951	63	0.33	103	0.59	21	0.10	40	0.24	56.5559673863466	0.390667476061019	-1.35598694194732	0.491482424227899	-2.75897341411043	0.00579832519581611	0.0311096985838503	Down	4	155493647	155551280	+	Cfap74	cilia and flagella associated protein 74 [Source:MGI Symbol%3BAcc:MGI:1917130]	GO:0035082:axoneme assembly;	GO:0005930:axoneme;	-	-	-
ENSMUSG00000043155	1804	17	0.49	4	0.13	54	1.38	25	0.83	24.3954930853881	3.8618448221057	1.94929019461575	0.707116144246044	2.75667612806969	0.00583921558649801	0.0312311831260716	Ups	4	116677101	116678904	-	Hpdl	4-hydroxyphenylpyruvate dioxygenase-like [Source:MGI Symbol%3BAcc:MGI:2444646]	GO:0009072:aromatic amino acid family metabolic process;	GO:0005739:mitochondrion;	GO:0003868:4-hydroxyphenylpyruvate dioxygenase activity;GO:0046872:metal ion binding;	-	-
ENSMUSG00000044024	3340	40	0.62	37	0.63	17	0.23	2	0.04	23.1336854562208	0.245546451950542	-2.02593211857829	0.734950081820669	-2.75655744341101	0.00584133515100908	0.0312311831260716	Down	18	38088132	38092232	+	Rell2	RELT-like 2 [Source:MGI Symbol%3BAcc:MGI:1918044]	GO:0010811:positive regulation of cell-substrate adhesion;GO:1900745:positive regulation of p38MAPK cascade;	GO:0005604:basement membrane;GO:0031012:extracellular matrix;GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0005518:collagen binding;	-	-
ENSMUSG00000021876	1637	14	0.44	17	0.59	2	0.06	1	0.04	8.28355469751967	0.099525017745793	-3.32879696621856	1.2085242401664	-2.75443127707577	0.00587942360147927	0.0314019789289736	Down	14	51328534	51343608	+	Rnase4	ribonuclease%2C RNase A family 4 [Source:MGI Symbol%3BAcc:MGI:1926217]	GO:0009267:cellular response to starvation;GO:0090501:RNA phosphodiester bond hydrolysis;	GO:0005576:extracellular region;GO:0005615:extracellular space;	GO:0004519:endonuclease activity;GO:0003676:nucleic acid binding;GO:0004540:ribonuclease activity;	K16632	-
ENSMUSG00000094344	345	24	3.61	25	4.12	74	9.87	43	7.42	40.907849149279	2.44638262742083	1.29065006678895	0.468849880302268	2.75280024803859	0.00590879366473131	0.0315368750626488	Ups	4	32964888	32965232	+	Gm11942	predicted gene 11942 [Source:MGI Symbol%3BAcc:MGI:3650608]	GO:0002181:cytoplasmic translation;GO:0006417:regulation of translation;GO:0006414:translational elongation;	GO:0005829:cytosol;GO:0022625:cytosolic large ribosomal subunit;	GO:0030295:protein kinase activator activity;GO:0043021:ribonucleoprotein complex binding;GO:0003735:structural constituent of ribosome;	K02942	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000007379	6858	2	0.02	7	0.06	18	0.12	28	0.24	14.1704686089678	5.40438432817534	2.43413027433734	0.884762382806468	2.75116836072559	0.00593831145246616	0.0316723714129099	Ups	3	103009920	103077085	+	Dennd2c	DENN/MADD domain containing 2C [Source:MGI Symbol%3BAcc:MGI:3036254]	-	GO:0005654:nucleoplasm;	GO:0005085:guanyl-nucleotide exchange factor activity;	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000064307	1210	43	1.84	34	1.60	17	0.65	5	0.25	23.929857973977	0.289726520598881	-1.78723634474475	0.650138090091027	-2.74901035946766	0.00597754969732453	0.0318594880287711	Down	7	101562191	101583102	-	Lrrc51	leucine rich repeat containing 51 [Source:MGI Symbol%3BAcc:MGI:1916608]	-	GO:0005737:cytoplasm;	-	-	-
ENSMUSG00000071658	1643	36	1.14	30	1.04	8	0.22	10	0.36	20.607792867792	0.2870597960405	-1.80057680584183	0.65571188847048	-2.74598773867266	0.00603290182921421	0.0320764620836237	Down	19	8814297	8816558	-	Gng3	guanine nucleotide binding protein (G protein)%2C gamma 3 [Source:MGI Symbol%3BAcc:MGI:102704]	GO:0007186:G-protein coupled receptor signaling pathway;	GO:0044297:cell body;GO:0030425:dendrite;GO:0031680:G-protein beta/gamma-subunit complex;GO:0005834:heterotrimeric G-protein complex;GO:0014069:postsynaptic density;	GO:0031681:G-protein beta-subunit binding;	K04540	;ko04014 Ras signaling pathway;ko04062 Chemokine signaling pathway;ko04151 PI3K-Akt signaling pathway;ko04371 Apelin signaling pathway;ko04713 Circadian entrainment;ko04723 Retrograde endocannabinoid signaling;ko04724 Glutamatergic synapse;ko04725 Cholinergic synapse;ko04726 Serotonergic synapse;ko04727 GABAergic synapse;ko04728 Dopaminergic synapse;ko04926 Relaxin signaling pathway;ko05032 Morphine addiction;ko05034 Alcoholism;ko05163 Human cytomegalovirus infection;ko05167 Kaposi sarcoma-associated herpesvirus infection;ko05170 Human immunodeficiency virus 1 infection;ko05200 Pathways in cancer;
ENSMUSG00000086665	1056	1	0.05	2	0.11	15	0.65	14	0.79	8.08973924053747	10.06334243147	3.33103765534011	1.21362957371754	2.74469057732057	0.00605679754387807	0.032170049718679	Ups	4	150132690	150141932	+	Gm13067	predicted gene 13067 [Source:MGI Symbol%3BAcc:MGI:3651968]	-	-	-	-	-
ENSMUSG00000032666	11788	15	0.07	20	0.10	47	0.18	44	0.22	31.6114359883315	2.70790663231902	1.4371779961461	0.523904526069487	2.74320591755202	0.00608425188131134	0.0323046808684308	Ups	1	151728154	151965876	-	1700025G04Rik	RIKEN cDNA 1700025G04 gene [Source:MGI Symbol%3BAcc:MGI:1916649]	-	-	-	-	-
ENSMUSG00000027603	3264	15	0.24	17	0.30	45	0.63	40	0.73	29.286637516596	2.76478555052132	1.46716758273927	0.536344044869148	2.73549710633445	0.0062286133951601	0.0329229775254688	Ups	2	155332299	155360157	-	Ggt7	gamma-glutamyltransferase 7 [Source:MGI Symbol%3BAcc:MGI:1913385]	GO:0006750:glutathione biosynthetic process;GO:0006751:glutathione catabolic process;GO:1902883:negative regulation of response to oxidative stress;GO:0032355:response to estradiol;GO:0032496:response to lipopolysaccharide;GO:0034612:response to tumor necrosis factor;GO:0007283:spermatogenesis;	GO:0016021:integral component of membrane;GO:0005886:plasma membrane;	GO:0036374:glutathione hydrolase activity;GO:0000048:peptidyltransferase activity;	K00681	;ko00430 Taurine and hypotaurine metabolism;ko00460 Cyanoamino acid metabolism;ko00480 Glutathione metabolism;ko01100 Metabolic pathways;
ENSMUSG00000116226	2110	48	1.18	60	1.62	11	0.24	24	0.68	35.5223889245786	0.346004396954112	-1.53113772343118	0.560646111215348	-2.73102353303055	0.00631379630462685	0.0333043524372714	Down	15	82069717	82071826	+	Gm49502	predicted gene%2C 49502 [Source:MGI Symbol%3BAcc:MGI:6155188]	-	-	-	-	-
ENSMUSG00000028573	5844	61	0.54	75	0.73	31	0.24	27	0.28	47.7657656804876	0.442711639930585	-1.17556078910605	0.430833576236692	-2.72857282706355	0.00636090429444495	0.0334800215473872	Down	4	95445744	95815176	+	Fggy	FGGY carbohydrate kinase domain containing [Source:MGI Symbol%3BAcc:MGI:1922828]	GO:0046835:carbohydrate phosphorylation;GO:0070050:neuron cellular homeostasis;GO:0019321:pentose metabolic process;	-	GO:0019150:D-ribulokinase activity;	-	-
ENSMUSG00000048027	7669	34	0.23	44	0.33	92	0.55	67	0.52	58.8436634814489	2.10221451149283	1.0719098904594	0.393430587883603	2.72452097897515	0.00643948391737736	0.0338161117770769	Ups	17	16023450	16051301	-	Rgmb	repulsive guidance molecule family member B [Source:MGI Symbol%3BAcc:MGI:1916049]	GO:0030509:BMP signaling pathway;GO:0007155:cell adhesion;GO:0045893:positive regulation of transcription, DNA-templated;GO:0007165:signal transduction;	GO:0046658:anchored component of plasma membrane;GO:0005793:endoplasmic reticulum-Golgi intermediate compartment;GO:0045121:membrane raft;GO:0005886:plasma membrane;	GO:0015026:coreceptor activity;GO:0042802:identical protein binding;	K06847	;ko04350 TGF-beta signaling pathway;
ENSMUSG00000025420	4061	14	0.18	14	0.20	1	0.01	1	0.01	7.30501078728885	0.0743823899383949	-3.74889508666379	1.37634793529797	-2.72379896864682	0.00645357756889919	0.0338669262291239	Down	18	77064844	77135004	-	Katnal2	katanin p60 subunit A-like 2 [Source:MGI Symbol%3BAcc:MGI:1924234]	GO:0031122:cytoplasmic microtubule organization;	GO:0005737:cytoplasm;GO:0005874:microtubule;GO:0005634:nucleus;GO:0005819:spindle;GO:0000922:spindle pole;	GO:0005524:ATP binding;GO:0016853:isomerase activity;GO:0008017:microtubule binding;GO:0008568:microtubule-severing ATPase activity;	K07767	-
ENSMUSG00000097331	2552	75	1.53	74	1.65	30	0.54	35	0.82	52.821267186019	0.458289713177108	-1.12566819170826	0.413317734538345	-2.72349356836956	0.00645954733337282	0.0338851909716563	Down	10	127031118	127038512	+	F420014N23Rik	RIKEN cDNA F420014N23 gene [Source:MGI Symbol%3BAcc:MGI:3642477]	-	-	-	-	-
ENSMUSG00000120245	1103	61	2.87	34	1.75	18	0.75	14	0.76	30.9171012476343	0.351623419352731	-1.50789693265731	0.553682812747206	-2.72339487147088	0.00646147765756639	0.0338851909716563	Down	5	105799203	105800305	+	-	novel transcript	-	-	-	-	-
ENSMUSG00000030507	2091	2	0.05	0	0.00	13	0.29	14	0.40	7.36681837767138	14.3016415304669	3.8381088427265	1.40949739049598	2.72303366335139	0.00646854662916612	0.0338990751919457	Ups	7	49281247	49286597	-	Dbx1	developing brain homeobox 1 [Source:MGI Symbol%3BAcc:MGI:94867]	GO:0021515:cell differentiation in spinal cord;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0021521:ventral spinal cord interneuron specification;	GO:0005634:nucleus;	GO:0003677:DNA binding;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;	K09311	-
ENSMUSG00000033577	12078	84	0.36	68	0.32	30	0.11	36	0.18	53.7256313559196	0.457681327211203	-1.12758466178499	0.41564568136545	-2.71285066184431	0.00667071614523711	0.0347684437019258	Down	9	80072313	80219011	+	Myo6	myosin VI [Source:MGI Symbol%3BAcc:MGI:104785]	GO:0007015:actin filament organization;GO:0030048:actin filament-based movement;GO:0030330:DNA damage response, signal transduction by p53 class mediator;GO:0006897:endocytosis;GO:0042491:auditory receptor cell differentiation;GO:0042472:inner ear morphogenesis;GO:0006886:intracellular protein transport;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0051046:regulation of secretion;GO:0042493:response to drug;GO:0007605:sensory perception of sound;GO:0030050:vesicle transport along actin filament;GO:0071257:cellular response to electrical stimulus;GO:0007268:synaptic transmission;GO:0016358:dendrite development;GO:0014047:glutamate secretion;GO:0048839:inner ear development;GO:0007626:locomotory behavior;GO:0006605:protein targeting;GO:0048167:regulation of synaptic plasticity;GO:2000300:regulation of synaptic vesicle exocytosis;GO:0007416:synapse assembly;	GO:0015629:actin cytoskeleton;GO:0005884:actin filament;GO:0045177:apical part of cell;GO:0005938:cell cortex;GO:0005905:coated pit;GO:0030665:clathrin-coated vesicle membrane;GO:0005737:cytoplasm;GO:0031410:cytoplasmic vesicle;GO:0005829:cytosol;GO:0030139:endocytic vesicle;GO:0070062:extracellular exosome;GO:0031941:filamentous actin;GO:0030175:filopodium;GO:0005794:Golgi apparatus;GO:0005765:lysosomal membrane;GO:0016020:membrane;GO:0005902:microvillus;GO:0031965:nuclear membrane;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0048471:perinuclear region of cytoplasm;GO:0005886:plasma membrane;GO:0016591:DNA-directed RNA polymerase II, holoenzyme;GO:0001726:ruffle;GO:0032587:ruffle membrane;GO:0016461:unconventional myosin complex;GO:0031982:vesicle;GO:0030424:axon;GO:0005903:brush border;GO:0030136:clathrin-coated vesicle;GO:0043231:intracellular membrane-bounded organelle;GO:0016459:myosin complex;GO:0043025:neuronal cell body;GO:0014069:postsynaptic density;GO:0032991:macromolecular complex;GO:0045202:synapse;GO:0012506:vesicle membrane;	GO:0003779:actin binding;GO:0051015:actin filament binding;GO:0043531:ADP binding;GO:0005524:ATP binding;GO:0005516:calmodulin binding;GO:0042802:identical protein binding;GO:0000146:microfilament motor activity;GO:0060001:minus-end directed microfilament motor activity;GO:0003774:motor activity;	K10358	;ko05130 Pathogenic Escherichia coli infection;ko05132 Salmonella infection;
ENSMUSG00000063568	2536	21	0.43	24	0.54	5	0.09	4	0.09	13.2083663722495	0.207281734082143	-2.27033510487596	0.837204732671333	-2.71180395460956	0.00669181573869437	0.0348547223291914	Down	6	52745782	53045616	-	Jazf1	JAZF zinc finger 1 [Source:MGI Symbol%3BAcc:MGI:2141450]	GO:0006629:lipid metabolic process;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;	GO:0005829:cytosol;GO:0001650:fibrillar center;GO:0005654:nucleoplasm;GO:0005634:nucleus;GO:0017053:transcriptional repressor complex;	GO:0046872:metal ion binding;GO:0003714:transcription corepressor activity;	K19495	-
ENSMUSG00000042104	12796	29	0.12	46	0.20	8	0.03	13	0.06	23.7873600657234	0.294974129539483	-1.76133966523236	0.650076715359142	-2.70943355394492	0.0067398203653311	0.0350537146527186	Down	14	119222451	119336842	-	Uggt2	UDP-glucose glycoprotein glucosyltransferase 2 [Source:MGI Symbol%3BAcc:MGI:1913685]	GO:0071712:ER-associated misfolded protein catabolic process;GO:0018279:protein N-linked glycosylation via asparagine;	GO:0005783:endoplasmic reticulum;GO:0005788:endoplasmic reticulum lumen;GO:0044322:endoplasmic reticulum quality control compartment;GO:0005793:endoplasmic reticulum-Golgi intermediate compartment;GO:0032991:macromolecular complex;	GO:0003980:UDP-glucose:glycoprotein glucosyltransferase activity;GO:0051082:unfolded protein binding;	K11718	;ko04141 Protein processing in endoplasmic reticulum;
ENSMUSG00000072949	3919	3	0.04	1	0.01	23	0.27	10	0.15	9.03392881645871	8.40987383820001	3.07208415786824	1.13440400488383	2.70810411867582	0.00676687895035656	0.0351740073982263	Ups	12	84056264	84065145	+	Acot1	acyl-CoA thioesterase 1 [Source:MGI Symbol%3BAcc:MGI:1349396]	GO:0006637:acyl-CoA metabolic process;GO:0006631:fatty acid metabolic process;GO:0001676:long-chain fatty acid metabolic process;GO:0010667:negative regulation of cardiac muscle cell apoptotic process;	GO:0005737:cytoplasm;GO:0005829:cytosol;GO:0005739:mitochondrion;	GO:0047617:acyl-CoA hydrolase activity;GO:0052689:carboxylic ester hydrolase activity;GO:0016290:palmitoyl-CoA hydrolase activity;	K01068	;ko00062 Fatty acid elongation;ko01040 Biosynthesis of unsaturated fatty acids;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko04913 Ovarian steroidogenesis;
ENSMUSG00000061723	1583	66	2.16	52	1.87	27	0.78	21	0.79	40.6108625609254	0.422939155110987	-1.24147796566386	0.459110379849265	-2.70409474530169	0.00684907572446147	0.0355410244192529	Down	7	142052573	142069746	+	Tnnt3	troponin T3%2C skeletal%2C fast [Source:MGI Symbol%3BAcc:MGI:109550]	GO:0006936:muscle contraction;GO:1903612:positive regulation of calcium-dependent ATPase activity;GO:0043462:regulation of ATPase activity;GO:0006937:regulation of muscle contraction;GO:0006942:regulation of striated muscle contraction;GO:0045214:sarcomere organization;GO:0003009:skeletal muscle contraction;	GO:0005861:troponin complex;GO:0005829:cytosol;	GO:0048306:calcium-dependent protein binding;GO:0005523:tropomyosin binding;GO:0030172:troponin C binding;GO:0031013:troponin I binding;GO:0031014:troponin T binding;	K12046	-
ENSMUSG00000085642	2205	16	0.38	17	0.44	41	0.86	45	1.22	29.9988011305731	2.73652725117825	1.45234622341694	0.537345461942639	2.70281657942423	0.00687546754776165	0.0356534931174348	Ups	12	20924126	20971263	-	3110053B16Rik	RIKEN cDNA 3110053B16 gene [Source:MGI Symbol%3BAcc:MGI:1920435]	-	GO:0016020:membrane;	GO:0005509:calcium ion binding;	K12488	;ko04144 Endocytosis;ko04666 Fc gamma R-mediated phagocytosis;
ENSMUSG00000027956	3487	75	1.12	74	1.21	18	0.24	38	0.65	50.9008572821623	0.40288506178094	-1.31155978082327	0.485570309151364	-2.70107079470221	0.00691166247706079	0.0357327823409474	Down	3	79719871	79760080	-	Tmem144	transmembrane protein 144 [Source:MGI Symbol%3BAcc:MGI:1917902]	-	GO:0016021:integral component of membrane;	GO:0015144:carbohydrate transmembrane transporter activity;	-	-
ENSMUSG00000028541	5031	5	0.05	0	0.00	22	0.20	15	0.18	10.4218080748963	7.72900642232474	2.95028296502776	1.09296768443133	2.69933229230176	0.00694787643359146	0.0358837107553693	Ups	4	117726457	117740684	-	B4galt2	UDP-Gal:betaGlcNAc beta 1%2C4- galactosyltransferase%2C polypeptide 2 [Source:MGI Symbol%3BAcc:MGI:1858493]	GO:0007420:brain development;GO:0005975:carbohydrate metabolic process;GO:0021680:cerebellar Purkinje cell layer development;GO:0070085:glycosylation;GO:0007626:locomotory behavior;GO:0007613:memory;GO:0006486:protein glycosylation;GO:0008542:visual learning;	GO:0005794:Golgi apparatus;GO:0032580:Golgi cisterna membrane;GO:0016021:integral component of membrane;GO:0043231:intracellular membrane-bounded organelle;GO:0005654:nucleoplasm;	GO:0003831:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;GO:0008378:galactosyltransferase activity;GO:0004461:lactose synthase activity;GO:0046872:metal ion binding;GO:0003945:N-acetyllactosamine synthase activity;	K07967	;ko00052 Galactose metabolism;ko00510 N-Glycan biosynthesis;ko00513 Various types of N-glycan biosynthesis;ko00514 Other types of O-glycan biosynthesis;ko00515 Mannose type O-glycan biosynthesis;ko00533 Glycosaminoglycan biosynthesis - keratan sulfate;ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series;ko01100 Metabolic pathways;
ENSMUSG00000032890	7972	41	0.27	20	0.14	81	0.47	57	0.43	49.1857724966487	2.35120561504305	1.23340070948513	0.457306798929311	2.69709681197149	0.00699469315654782	0.036101186422923	Ups	4	120712013	120753776	+	Rims3	regulating synaptic membrane exocytosis 3 [Source:MGI Symbol%3BAcc:MGI:2443331]	GO:0048791:calcium ion-dependent exocytosis of neurotransmitter;GO:0017156:calcium ion-dependent exocytosis;GO:0050806:positive regulation of synaptic transmission;GO:0042391:regulation of membrane potential;GO:0050807:regulation of synapse organization;GO:0048167:regulation of synaptic plasticity;GO:2000300:regulation of synaptic vesicle exocytosis;	GO:0048788:presynaptic cytoskeletal matrix assembled at active zones;GO:0042734:presynaptic membrane;	GO:0031267:small GTPase binding;GO:0044325:ion channel binding;	K15298	-
ENSMUSG00000059498	1736	1	0.03	1	0.03	15	0.40	11	0.38	7.00282983119346	13.4460593883366	3.74911152165555	1.39116611198776	2.69494166753289	0.00704009546792251	0.0362744703982271	Ups	1	170878743	170892504	-	Fcgr3	Fc receptor%2C IgG%2C low affinity III [Source:MGI Symbol%3BAcc:MGI:95500]	GO:0001788:antibody-dependent cellular cytotoxicity;GO:0042590:antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0007166:cell surface receptor signaling pathway;GO:0045576:mast cell activation;GO:0030593:neutrophil chemotaxis;GO:0006911:phagocytosis, engulfment;GO:0006910:phagocytosis, recognition;GO:0050766:positive regulation of phagocytosis;GO:0032760:positive regulation of tumor necrosis factor production;GO:0001812:positive regulation of type I hypersensitivity;GO:0001798:positive regulation of type IIa hypersensitivity;GO:0001805:positive regulation of type III hypersensitivity;GO:0050776:regulation of immune response;GO:0001820:serotonin secretion;GO:0021675:nerve development;GO:0001813:regulation of antibody-dependent cellular cytotoxicity;GO:0032680:regulation of tumor necrosis factor production;	GO:0009986:cell surface;GO:0009897:external side of plasma membrane;GO:0005794:Golgi apparatus;GO:0005887:integral component of plasma membrane;GO:0005886:plasma membrane;	GO:0019864:IgG binding;GO:0019770:IgG receptor activity;GO:0034987:immunoglobulin receptor binding;GO:0004888:transmembrane signaling receptor activity;	K16824	;ko04145 Phagosome;ko04380 Osteoclast differentiation;ko05140 Leishmaniasis;ko05150 Staphylococcus aureus infection;ko05152 Tuberculosis;
ENSMUSG00000120693	1293	33	1.32	45	1.98	14	0.50	11	0.51	25.3018623818744	0.33129421164373	-1.59381509794546	0.591956459555957	-2.69245325769571	0.0070928477174887	0.0364482998994544	Down	9	123725016	123726308	+	-	novel transcript	-	-	-	-	-
ENSMUSG00000097797	4339	29	0.35	13	0.17	80	0.85	35	0.48	38.2381939207833	2.79476329553153	1.48272609815831	0.553566333832125	2.6784976027967	0.00739532615257602	0.0377999770745336	Ups	1	7419630	7468093	-	Gm26901	predicted gene%2C 26901 [Source:MGI Symbol%3BAcc:MGI:5477395]	-	-	-	-	-
ENSMUSG00000004562	10366	22	0.11	28	0.15	71	0.32	45	0.26	41.0536520749106	2.38042153892204	1.25121707700449	0.467328600752489	2.67738177160523	0.00742000344171865	0.0379008436959739	Ups	14	52222176	52243708	+	Arhgef40	Rho guanine nucleotide exchange factor (GEF) 40 [Source:MGI Symbol%3BAcc:MGI:2685515]	-	GO:0005829:cytosol;GO:0005886:plasma membrane;	GO:0005085:guanyl-nucleotide exchange factor activity;	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000030935	4936	37	0.39	23	0.27	11	0.10	4	0.05	18.1113802524707	0.255833525318318	-1.9667227624846	0.735000057680385	-2.67581307230295	0.00745482109320739	0.0380660095382092	Down	7	119360146	119386736	+	Acsm3	acyl-CoA synthetase medium-chain family member 3 [Source:MGI Symbol%3BAcc:MGI:99538]	GO:0006633:fatty acid biosynthetic process;GO:0006637:acyl-CoA metabolic process;	GO:0005759:mitochondrial matrix;GO:0005739:mitochondrion;	GO:0005524:ATP binding;GO:0047760:butyrate-CoA ligase activity;GO:0046872:metal ion binding;GO:0043759:branched-chain acyl-CoA synthetase (ADP-forming) activity;GO:0018729:propionate CoA-transferase activity;GO:0050218:propionate-CoA ligase activity;GO:0015645:fatty acid ligase activity;GO:0004321:fatty-acyl-CoA synthase activity;	K01896	;ko00650 Butanoate metabolism;ko01100 Metabolic pathways;
ENSMUSG00000115961	1072	9	0.44	12	0.64	50	2.15	21	1.17	22.4695617858232	3.41450419416475	1.77167610602639	0.662244733962363	2.67525888114812	0.00746715647889008	0.0381163040769975	Ups	16	3588318	3603593	+	Gm41409	predicted gene%2C 41409 [Source:MGI Symbol%3BAcc:MGI:5624294]	-	-	-	-	-
ENSMUSG00000051716	1801	21	0.61	25	0.79	3	0.08	6	0.20	13.5565414397487	0.207032521754607	-2.27207068325571	0.849501732812505	-2.67459217032248	0.00748202062310591	0.038166767875817	Down	10	128089965	128091765	+	Apon	apolipoprotein N [Source:MGI Symbol%3BAcc:MGI:88931]	-	-	-	-	-
ENSMUSG00000033174	5077	90	0.92	72	0.81	250	2.27	86	1.01	120.653222517537	2.08448251560706	1.05968927104159	0.396328302502292	2.67376633046655	0.00750046929467537	0.0382250752585021	Ups	6	88701394	88805342	+	Mgll	monoglyceride lipase [Source:MGI Symbol%3BAcc:MGI:1346042]	GO:0046464:acylglycerol catabolic process;GO:0019369:arachidonic acid metabolic process;GO:0006633:fatty acid biosynthetic process;GO:0060292:long term synaptic depression;GO:0052651:monoacylglycerol catabolic process;GO:0045907:positive regulation of vasoconstriction;GO:0030516:regulation of axon extension;GO:2000124:regulation of endocannabinoid signaling pathway;GO:0050727:regulation of inflammatory response;GO:0051930:regulation of sensory perception of pain;GO:0009966:regulation of signal transduction;GO:0019433:triglyceride catabolic process;	GO:0030424:axon;GO:0005829:cytosol;GO:0019898:extrinsic component of membrane;GO:0016020:membrane;GO:0005654:nucleoplasm;GO:0045202:synapse;GO:0043196:varicosity;GO:0005811:lipid particle;	GO:0047372:acylglycerol lipase activity;GO:0016787:hydrolase activity;GO:0016298:lipase activity;GO:0042803:protein homodimerization activity;	K01054	;ko00561 Glycerolipid metabolism;ko01100 Metabolic pathways;ko04714 Thermogenesis;ko04723 Retrograde endocannabinoid signaling;ko04923 Regulation of lipolysis in adipocytes;
ENSMUSG00000024253	1869	28	0.78	34	1.04	8	0.20	9	0.29	19.4401314938466	0.286550171085867	-1.80314033726684	0.674906709486365	-2.67168826731493	0.00754707233152323	0.0383964190881145	Down	17	84933924	84963016	+	Dync2li1	dynein cytoplasmic 2 light intermediate chain 1 [Source:MGI Symbol%3BAcc:MGI:1913996]	GO:0060271:cilium morphogenesis;GO:0007368:determination of left/right symmetry;GO:0035721:intraciliary retrograde transport;GO:0035735:intraciliary transport involved in cilium morphogenesis;GO:1902017:regulation of cilium assembly;	GO:0045177:apical part of cell;GO:0005930:axoneme;GO:0005813:centrosome;GO:0036064:ciliary basal body;GO:0035869:ciliary transition zone;GO:0005737:cytoplasm;GO:0005868:cytoplasmic dynein complex;GO:0005874:microtubule;GO:0031514:motile cilium;	GO:0045504:dynein heavy chain binding;	K10417	;ko04962 Vasopressin-regulated water reabsorption;ko05132 Salmonella infection;
ENSMUSG00000045659	12933	12	0.05	13	0.06	41	0.15	31	0.14	24.1495120611423	2.98018737346349	1.57540304017347	0.589716946012678	2.67145628224766	0.00755229094868768	0.0384102253423472	Ups	7	115722720	115907611	-	Plekha7	pleckstrin homology domain containing%2C family A member 7 [Source:MGI Symbol%3BAcc:MGI:2445094]	GO:0044331:cell-cell adhesion mediated by cadherin;GO:0090136:epithelial cell-cell adhesion;GO:0046931:pore complex assembly;GO:0045218:zonula adherens maintenance;	GO:0030054:cell junction;GO:0005911:cell-cell junction;GO:0005813:centrosome;GO:0005829:cytosol;GO:0005654:nucleoplasm;GO:0046930:pore complex;GO:0005915:zonula adherens;	GO:0070097:delta-catenin binding;	-	-
ENSMUSG00000032340	8716	4	0.02	2	0.01	18	0.10	17	0.12	10.3240793273457	6.11966829030413	2.61345345538479	0.979895614557987	2.66707332552322	0.00765149760184829	0.0388246407103712	Ups	9	58781970	58943724	-	Neo1	neogenin [Source:MGI Symbol%3BAcc:MGI:1097159]	GO:0007411:axon guidance;GO:0007155:cell adhesion;GO:0055072:iron ion homeostasis;GO:0007520:myoblast fusion;GO:0048681:negative regulation of axon regeneration;GO:1901215:negative regulation of neuron death;GO:0050709:negative regulation of protein secretion;GO:0001764:neuron migration;GO:0030513:positive regulation of BMP signaling pathway;GO:0048679:regulation of axon regeneration;GO:2001222:regulation of neuron migration;GO:0006355:regulation of transcription, DNA-templated;	GO:0009986:cell surface;GO:0005794:Golgi apparatus;GO:0005887:integral component of plasma membrane;GO:0016020:membrane;GO:0043025:neuronal cell body;GO:0005654:nucleoplasm;GO:0005886:plasma membrane;GO:0098797:plasma membrane protein complex;	GO:0070700:BMP receptor binding;GO:0045296:cadherin binding;GO:0039706:co-receptor binding;GO:0038023:signaling receptor activity;	K06766	;ko04350 TGF-beta signaling pathway;ko04360 Axon guidance;ko04514 Cell adhesion molecules;
ENSMUSG00000032374	5392	40	0.39	34	0.36	66	0.56	85	0.94	56.8119197074742	2.16142834717541	1.11198501070149	0.417151592663644	2.66566166894177	0.00768369773261748	0.0389493623246137	Ups	9	92424276	92490481	+	Plod2	procollagen lysine%2C 2-oxoglutarate 5-dioxygenase 2 [Source:MGI Symbol%3BAcc:MGI:1347007]	GO:0046947:hydroxylysine biosynthetic process;GO:0017185:peptidyl-lysine hydroxylation;	GO:0005783:endoplasmic reticulum;GO:0030867:rough endoplasmic reticulum membrane;	GO:0005506:iron ion binding;GO:0031418:L-ascorbic acid binding;GO:0008475:procollagen-lysine 5-dioxygenase activity;	K13645	;ko00310 Lysine degradation;ko01100 Metabolic pathways;
ENSMUSG00000032487	4580	23	0.26	4	0.05	40	0.40	49	0.64	29.291928965216	3.53227631105039	1.8205982017039	0.684050659613855	2.66149615692443	0.00777942289764335	0.0393695282879416	Ups	1	149975782	149983978	+	Ptgs2	prostaglandin-endoperoxide synthase 2 [Source:MGI Symbol%3BAcc:MGI:97798]	GO:0007568:aging;GO:0001525:angiogenesis;GO:0030282:bone mineralization;GO:0050873:brown fat cell differentiation;	GO:0005901:caveola;GO:0005737:cytoplasm;GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0043005:neuron projection;GO:0005637:nuclear inner membrane;	GO:0019899:enzyme binding;GO:0020037:heme binding;GO:0046872:metal ion binding;GO:0016702:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;	K11987	;ko00590 Arachidonic acid metabolism;ko01100 Metabolic pathways;ko04064 NF-kappa B signaling pathway;ko04370 VEGF signaling pathway;ko04625 C-type lectin receptor signaling pathway;ko04657 IL-17 signaling pathway;ko04668 TNF signaling pathway;ko04723 Retrograde endocannabinoid signaling;ko04726 Serotonergic synapse;ko04913 Ovarian steroidogenesis;ko04921 Oxytocin signaling pathway;ko04923 Regulation of lipolysis in adipocytes;ko05010 Alzheimer disease;ko05022 Pathways of neurodegeneration - multiple diseases;ko05140 Leishmaniasis;ko05163 Human cytomegalovirus infection;ko05165 Human papillomavirus infection;ko05167 Kaposi sarcoma-associated herpesvirus infection;ko05200 Pathways in cancer;ko05204 Chemical carcinogenesis;ko05206 MicroRNAs in cancer;ko05222 Small cell lung cancer;
ENSMUSG00000066677	5258	53	0.52	202	2.19	19	0.17	22	0.25	73.4219349351489	0.166772530607638	-2.5840464153357	0.972059827768083	-2.65832034358302	0.00785312079724769	0.0396770195403611	Down	1	173501241	173525961	+	Ifi208	interferon activated gene 208 [Source:MGI Symbol%3BAcc:MGI:2442822]	GO:0002218:activation of innate immune response;GO:0035458:cellular response to interferon-beta;	GO:0005829:cytosol;GO:0005730:nucleolus;GO:0005654:nucleoplasm;GO:0005634:nucleus;	GO:0001227:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003690:double-stranded DNA binding;GO:0042802:identical protein binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	-	-
ENSMUSG00000074738	2140	6	0.15	4	0.11	26	0.56	18	0.50	13.4125543992049	4.55343695203929	2.18695590835621	0.822752384848773	2.65809731898642	0.00785831973137257	0.0396902090780194	Ups	4	155778799	155780938	+	Fndc10	fibronectin type III domain containing 10 [Source:MGI Symbol%3BAcc:MGI:2444790]	-	GO:0016021:integral component of membrane;	-	-	-
ENSMUSG00000100838	664	61	4.77	46	3.94	29	2.01	8	0.72	34.7652955962906	0.349122127399369	-1.51819629692631	0.57164296965277	-2.6558470540598	0.00791094848194684	0.0399297182429799	Down	9	89081432	89097524	+	Gm29094	predicted gene 29094 [Source:MGI Symbol%3BAcc:MGI:5579800]	GO:0001782:B cell homeostasis;GO:0097192:extrinsic apoptotic signaling pathway in absence of ligand;GO:0008630:intrinsic apoptotic signaling pathway in response to DNA damage;GO:0043066:negative regulation of apoptotic process;GO:0002903:negative regulation of B cell apoptotic process;	GO:0005741:mitochondrial outer membrane;	GO:0051400:BH domain binding;GO:0046982:protein heterodimerization activity;GO:0042803:protein homodimerization activity;GO:0044877:macromolecular complex binding;	K02162	;ko04064 NF-kappa B signaling pathway;ko04210 Apoptosis;ko05202 Transcriptional misregulation in cancer;ko05221 Acute myeloid leukemia;
ENSMUSG00000005413	1751	77	2.28	112	3.64	56	1.47	33	1.12	68.193808108041	0.481401586528648	-1.05468719845667	0.397579044195567	-2.65277361534648	0.00798333945905537	0.0402288949277539	Down	8	75820249	75827217	+	Hmox1	heme oxygenase 1 [Source:MGI Symbol%3BAcc:MGI:96163]	GO:0001525:angiogenesis;GO:0008219:cell death;GO:0006879:cellular iron ion homeostasis;GO:0071243:cellular response to arsenic-containing substance;GO:0071276:cellular response to cadmium ion;GO:0072719:cellular response to cisplatin;GO:0034605:cellular response to heat;GO:0071456:cellular response to hypoxia;GO:0031670:cellular response to nutrient;GO:0034101:erythrocyte homeostasis;GO:0042167:heme catabolic process;GO:0042168:heme metabolic process;GO:0006788:heme oxidation;GO:0035556:intracellular signal transduction;GO:0008630:intrinsic apoptotic signaling pathway in response to DNA damage;GO:0055072:iron ion homeostasis;GO:0097421:liver regeneration;GO:0008285:negative regulation of cell proliferation;GO:0043392:negative regulation of DNA binding;GO:0043433:negative regulation of sequence-specific DNA binding transcription factor activity;GO:1904036:negative regulation of epithelial cell apoptotic process;GO:1902042:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0016242:negative regulation of macroautophagy;GO:0032764:negative regulation of mast cell cytokine production;GO:0043305:negative regulation of mast cell degranulation;GO:0010656:negative regulation of muscle cell apoptotic process;GO:0043524:negative regulation of neuron apoptotic process;GO:0048662:negative regulation of smooth muscle cell proliferation;GO:0045766:positive regulation of angiogenesis;GO:0043065:positive regulation of apoptotic process;GO:1903589:positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0090050:positive regulation of cell migration involved in sprouting angiogenesis;GO:0016239:positive regulation of macroautophagy;GO:0048661:positive regulation of smooth muscle cell proliferation;GO:0008217:regulation of blood pressure;GO:0051090:regulation of sequence-specific DNA binding transcription factor activity;GO:0034395:regulation of transcription from RNA polymerase II promoter in response to iron;GO:0043619:regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0042493:response to drug;GO:0043627:response to estrogen;GO:0042542:response to hydrogen peroxide;GO:0001666:response to hypoxia;GO:0035094:response to nicotine;GO:0006979:response to oxidative stress;GO:0007264:small GTPase mediated signal transduction;GO:0002246:wound healing involved in inflammatory response;	GO:0005901:caveola;GO:0005829:cytosol;GO:0005783:endoplasmic reticulum;GO:0005789:endoplasmic reticulum membrane;GO:0005730:nucleolus;GO:0005634:nucleus;GO:0048471:perinuclear region of cytoplasm;	GO:0019899:enzyme binding;GO:0020037:heme binding;GO:0004392:heme oxygenase (decyclizing) activity;GO:0042802:identical protein binding;GO:0046872:metal ion binding;GO:0004630:phospholipase D activity;GO:0042803:protein homodimerization activity;GO:0005198:structural molecule activity;	K00510	;ko00860 Porphyrin and chlorophyll metabolism;ko01100 Metabolic pathways;ko01110 Biosynthesis of secondary metabolites;ko04066 HIF-1 signaling pathway;ko04216 Ferroptosis;ko04978 Mineral absorption;ko05200 Pathways in cancer;ko05206 MicroRNAs in cancer;ko05225 Hepatocellular carcinoma;ko05418 Fluid shear stress and atherosclerosis;
ENSMUSG00000114934	1899	30	0.82	25	0.75	1	0.02	9	0.28	16.0569674785155	0.198769418956079	-2.33083228222328	0.878807150523664	-2.65226822612263	0.00799529989223416	0.0402671584432224	Down	13	120159896	120166085	-	Gm48342	predicted gene%2C 48342 [Source:MGI Symbol%3BAcc:MGI:6097804]	-	-	-	-	-
ENSMUSG00000021013	3782	53	0.73	59	0.89	29	0.35	16	0.25	38.3558266120176	0.411812129461721	-1.27994177133642	0.483044985783411	-2.64973617159195	0.00805546485975593	0.0404991797244254	Down	12	98886833	98949497	+	Ttc8	tetratricopeptide repeat domain 8 [Source:MGI Symbol%3BAcc:MGI:1923510]	GO:0007411:axon guidance;GO:0060219:camera-type eye photoreceptor cell differentiation;GO:0060271:cilium morphogenesis;GO:0048560:establishment of anatomical structure orientation;GO:0045198:establishment of epithelial cell apical/basal polarity;GO:0001736:establishment of planar polarity;GO:0045444:fat cell differentiation;GO:0060122:inner ear receptor stereocilium organization;GO:1903251:multi-ciliated epithelial cell differentiation;GO:0035264:multicellular organism growth;GO:0034260:negative regulation of GTPase activity;GO:0021772:olfactory bulb development;GO:0072659:protein localization to plasma membrane;GO:0015031:protein transport;GO:0032880:regulation of protein localization;GO:0051492:regulation of stress fiber assembly;GO:0061326:renal tubule development;GO:0007608:sensory perception of smell;	GO:0034464:BBSome;GO:0005814:centriole;GO:0005813:centrosome;GO:0036064:ciliary basal body;GO:0060170:ciliary membrane;GO:0005929:cilium;GO:0005737:cytoplasm;GO:0016020:membrane;GO:0032391:photoreceptor connecting cilium;	GO:0061629:RNA polymerase II sequence-specific DNA binding transcription factor binding;	K16781	-
ENSMUSG00000102863	2785	31	0.58	46	0.94	6	0.10	15	0.32	24.3576728059532	0.291049237233685	-1.78066485823478	0.672309512439507	-2.64857900310462	0.00808309541854491	0.0405981608738839	Down	17	71673047	71675831	-	Gm37639	predicted gene%2C 37639 [Source:MGI Symbol%3BAcc:MGI:5610867]	-	-	-	-	-
ENSMUSG00000054057	3378	20	0.31	24	0.40	6	0.08	3	0.05	12.9232100021346	0.209633133899123	-2.25406133252521	0.852574203718633	-2.64383008856447	0.00819737939717347	0.0410377458949585	Down	2	18030004	18042548	-	A930004D18Rik	RIKEN cDNA A930004D18 gene [Source:MGI Symbol%3BAcc:MGI:1925190]	-	-	-	-	-
ENSMUSG00000024910	1887	16	0.44	7	0.21	33	0.80	37	1.17	23.4316474283659	3.22310259074596	1.68845010983863	0.639361375241421	2.64083846041071	0.00827011410776109	0.0413613599896962	Ups	19	5515071	5518535	-	Ctsw	cathepsin W [Source:MGI Symbol%3BAcc:MGI:1338045]	GO:0051603:proteolysis involved in cellular protein catabolic process;	GO:0005783:endoplasmic reticulum;GO:0005615:extracellular space;GO:0005764:lysosome;	GO:0004197:cysteine-type endopeptidase activity;	K08569	;ko04142 Lysosome;ko04210 Apoptosis;
ENSMUSG00000079645	691	72	5.41	73	6.01	31	2.06	34	2.93	51.8148184226269	0.469847309153982	-1.08973610855827	0.412870572981683	-2.63941336552124	0.00830496470986215	0.0415221157029756	Down	12	84969316	84970286	-	Gm17193	predicted gene 17193 [Source:MGI Symbol%3BAcc:MGI:4938020]	-	-	-	-	-
ENSMUSG00000034009	10052	21	0.11	33	0.19	6	0.03	7	0.04	16.5217064931913	0.251033455872227	-1.99404844623124	0.755544679040374	-2.63921975966253	0.00830970945222594	0.0415322961996195	Down	3	79548918	79645187	-	Rxfp1	relaxin/insulin-like family peptide receptor 1 [Source:MGI Symbol%3BAcc:MGI:2682211]	GO:0007190:activation of adenylate cyclase activity;GO:0007189:adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007188:adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0030154:cell differentiation;GO:0030198:extracellular matrix organization;GO:0009755:hormone-mediated signaling pathway;GO:0060427:lung connective tissue development;GO:0060658:nipple morphogenesis;GO:0007567:parturition;	GO:0005887:integral component of plasma membrane;	GO:0008528:G-protein coupled peptide receptor activity;GO:0004930:G-protein coupled receptor activity;GO:0042562:hormone binding;GO:0046872:metal ion binding;	K04306	;ko04080 Neuroactive ligand-receptor interaction;ko04926 Relaxin signaling pathway;
ENSMUSG00000031391	7347	24	0.17	29	0.22	9	0.06	4	0.03	16.0830730407647	0.25041969298424	-1.99758007473522	0.757158345586629	-2.63825933687297	0.00833328262380847	0.0416094287702635	Down	X	72897384	72939711	-	L1cam	L1 cell adhesion molecule [Source:MGI Symbol%3BAcc:MGI:96721]	GO:0061564:axon development;GO:0007411:axon guidance;GO:0007413:axonal fasciculation;GO:0016477:cell migration;GO:0007166:cell surface receptor signaling pathway;GO:0033631:cell-cell adhesion mediated by integrin;GO:0007160:cell-matrix adhesion;GO:0007157:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007156:homophilic cell adhesion via plasma membrane adhesion molecules;GO:0034109:homotypic cell-cell adhesion;GO:0007159:leukocyte cell-cell adhesion;GO:0050804:regulation of synaptic transmission;GO:0031175:neuron projection development;GO:0045773:positive regulation of axon extension;GO:0050850:positive regulation of calcium-mediated signaling;GO:0022409:positive regulation of cell-cell adhesion;GO:0010811:positive regulation of cell-substrate adhesion;GO:0070372:regulation of ERK1 and ERK2 cascade;GO:0050808:synapse organization;GO:0071549:cellular response to dexamethasone stimulus;GO:0071361:cellular response to ethanol;GO:1990090:cellular response to nerve growth factor stimulus;GO:0097069:cellular response to thyroxine stimulus;GO:0071560:cellular response to transforming growth factor beta stimulus;GO:0071542:dopaminergic neuron differentiation;GO:0030182:neuron differentiation;GO:0014823:response to activity;GO:0097066:response to thyroid hormone;GO:0007155:cell adhesion;GO:0006935:chemotaxis;GO:0007399:nervous system development;	GO:0030424:axon;GO:0044295:axonal growth cone;GO:0009986:cell surface;GO:0030425:dendrite;GO:0044294:dendritic growth cone;GO:0005768:endosome;GO:0009897:external side of plasma membrane;GO:0016021:integral component of membrane;GO:0016020:membrane;GO:0045121:membrane raft;GO:0043025:neuronal cell body;GO:0005886:plasma membrane;GO:0042734:presynaptic membrane;GO:0043195:terminal bouton;GO:0005925:focal adhesion;	GO:0008046:axon guidance receptor activity;GO:0042802:identical protein binding;GO:0005178:integrin binding;GO:0030165:PDZ domain binding;GO:0019904:protein domain specific binding;GO:0043621:protein self-association;GO:0033691:sialic acid binding;	K06550	;ko04360 Axon guidance;ko04514 Cell adhesion molecules;
ENSMUSG00000097141	1893	77	2.11	44	1.32	23	0.56	24	0.76	41.1267610916877	0.409200998784749	-1.28911842844526	0.488687545174547	-2.63791954833802	0.00834163690554719	0.0416375847362177	Down	18	82710409	82712301	+	Gm10524	predicted gene 10524 [Source:MGI Symbol%3BAcc:MGI:3642791]	-	-	-	-	-
ENSMUSG00000040899	2320	2599	58.16	2581	63.31	741	14.70	1235	31.70	1772.14511138151	0.409535527040173	-1.28793948438506	0.488451510316121	-2.63678063673407	0.00836969366455827	0.0417504497893092	Down	17	8454875	8475973	+	Ccr6	chemokine (C-C motif) receptor 6 [Source:MGI Symbol%3BAcc:MGI:1333797]	GO:0019722:calcium-mediated signaling;GO:0060326:cell chemotaxis;GO:0006935:chemotaxis;GO:1904155:DN2 thymocyte differentiation;GO:1904156:DN3 thymocyte differentiation;GO:0006955:immune response;GO:0048290:isotype switching to IgA isotypes;GO:0002523:leukocyte migration involved in inflammatory response;GO:0072676:lymphocyte migration;GO:0007204:positive regulation of cytosolic calcium ion concentration;GO:2000510:positive regulation of dendritic cell chemotaxis;GO:0010634:positive regulation of epithelial cell migration;GO:0060474:positive regulation of sperm motility involved in capacitation;GO:2000404:regulation of T cell migration;GO:0072678:T cell migration;GO:0072679:thymocyte migration;	GO:0009986:cell surface;GO:0009897:external side of plasma membrane;GO:0016021:integral component of membrane;GO:0036126:sperm flagellum;GO:0097225:sperm midpiece;GO:0097524:sperm plasma membrane;GO:0097228:sperm principal piece;	GO:0019957:C-C chemokine binding;GO:0016493:C-C chemokine receptor activity;	K04181	;ko04060 Cytokine-cytokine receptor interaction;ko04061 Viral protein interaction with cytokine and cytokine receptor;ko04062 Chemokine signaling pathway;
ENSMUSG00000105881	3346	73	1.13	75	1.28	30	0.41	36	0.64	52.8782401963121	0.468748089085674	-1.09311528571893	0.415495097196317	-2.63087408995934	0.00851655819866753	0.0422684107593165	Down	5	123276764	123280109	+	4932422M17Rik	RIKEN cDNA 4932422M17 gene [Source:MGI Symbol%3BAcc:MGI:1921616]	-	-	-	-	-
ENSMUSG00000114141	706	61	4.49	60	4.84	18	1.17	29	2.45	41.5927728600957	0.412253118283032	-1.2783976886365	0.486490601909753	-2.62779524130182	0.00859402283947682	0.0424825100646478	Down	12	36376327	36381935	+	Gm34215	predicted gene%2C 34215 [Source:MGI Symbol%3BAcc:MGI:5593374]	-	-	-	-	-
ENSMUSG00000050390	5770	14	0.13	26	0.26	62	0.49	40	0.41	35.2037773425351	2.60871224850329	1.38333781784178	0.526905826427809	2.62539859773463	0.00865475837127636	0.0426825528809693	Ups	4	129113371	129155197	-	C77080	expressed sequence C77080 [Source:MGI Symbol%3BAcc:MGI:2140651]	GO:0030154:cell differentiation;	-	-	-	-
ENSMUSG00000085579	443	75	8.79	76	9.76	40	4.15	31	4.17	54.5020974685778	0.487390938996419	-1.03684866447946	0.395260216418185	-2.62320522382772	0.00871067857840996	0.0428334696552237	Down	11	24151418	24167601	+	Gm12066	predicted gene 12066 [Source:MGI Symbol%3BAcc:MGI:3649818]	-	-	-	-	-
ENSMUSG00000068130	2922	63	1.12	84	1.64	11	0.17	37	0.75	48.6785471979752	0.35402553821408	-1.49807465964723	0.571101146001949	-2.62313369555403	0.00871250762062362	0.0428334696552237	Down	2	150249061	150293406	-	Zfp442	zinc finger protein 442 [Source:MGI Symbol%3BAcc:MGI:3651999]	GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0030154:cell differentiation;GO:0043433:negative regulation of sequence-specific DNA binding transcription factor activity;GO:0045668:negative regulation of osteoblast differentiation;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;	GO:0005634:nucleus;	GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046872:metal ion binding;GO:0000977:RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003682:chromatin binding;GO:0042826:histone deacetylase binding;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;	K09228	;ko05168 Herpes simplex virus 1 infection;
ENSMUSG00000102805	4754	1	0.01	1	0.01	15	0.15	10	0.13	6.72371914816992	12.8799097570555	3.68705058014854	1.40571538156538	2.62289979074049	0.00871849117336923	0.042843922381042	Ups	3	84403733	85794825	-	Gm37240	predicted gene%2C 37240 [Source:MGI Symbol%3BAcc:MGI:5610468]	GO:0006886:intracellular protein transport;GO:0034315:regulation of Arp2/3 complex-mediated actin nucleation;GO:0050708:regulation of protein secretion;	GO:0005829:cytosol;GO:0000139:Golgi membrane;GO:0032588:trans-Golgi network membrane;	GO:0070273:phosphatidylinositol-4-phosphate binding;GO:0005543:phospholipid binding;GO:0019904:protein domain specific binding;	-	-
ENSMUSG00000035158	6196	40	0.34	37	0.34	14	0.10	12	0.12	25.2353567982243	0.351442399773599	-1.50863983907598	0.57576704681935	-2.62022609214959	0.00878714880556245	0.0430899071904364	Down	6	97784013	97998310	+	Mitf	melanogenesis associated transcription factor [Source:MGI Symbol%3BAcc:MGI:104554]	GO:0046849:bone remodeling;GO:0043010:camera-type eye development;GO:0044336:canonical Wnt signaling pathway involved in negative regulation of apoptotic process;GO:0030154:cell differentiation;GO:0045165:cell fate commitment;GO:0030318:melanocyte differentiation;GO:0043066:negative regulation of apoptotic process;GO:0030336:negative regulation of cell migration;GO:0000122:negative regulation of transcription from RNA polymerase II promoter;GO:0030316:osteoclast differentiation;GO:0043473:pigmentation;GO:2000144:positive regulation of DNA-templated transcription, initiation;GO:0010628:positive regulation of gene expression;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0045893:positive regulation of transcription, DNA-templated;GO:0065003:macromolecular complex assembly;GO:0042127:regulation of cell proliferation;GO:0010468:regulation of gene expression;GO:0045670:regulation of osteoclast differentiation;GO:2001141:regulation of RNA biosynthetic process;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0006355:regulation of transcription, DNA-templated;GO:0006351:transcription, DNA-templated;GO:0016055:Wnt signaling pathway;	GO:0005737:cytoplasm;GO:0005634:nucleus;GO:0032991:macromolecular complex;	GO:0003682:chromatin binding;GO:0003677:DNA binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003700:sequence-specific DNA binding transcription factor activity;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0070888:E-box binding;GO:0046983:protein dimerization activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043565:sequence-specific DNA binding;	K09455	;ko04137 Mitophagy - animal;ko04380 Osteoclast differentiation;ko04916 Melanogenesis;ko05200 Pathways in cancer;ko05202 Transcriptional misregulation in cancer;ko05218 Melanoma;
ENSMUSG00000099137	7007	72	0.53	97	0.79	28	0.18	44	0.37	59.906346411192	0.450918028873417	-1.14906290106565	0.438701374570326	-2.61923706573991	0.00881266805757372	0.0431736268354107	Down	7	100095944	100124053	-	Gm10603	predicted gene 10603 [Source:MGI Symbol%3BAcc:MGI:3642592]	-	-	-	-	-
ENSMUSG00000029869	3773	39	0.54	35	0.53	17	0.21	6	0.09	23.5151159512662	0.315999272061434	-1.66200685988552	0.634799006716236	-2.61816235107699	0.00884047332068498	0.0432767514289081	Down	6	41582416	41597443	+	Ephb6	Eph receptor B6 [Source:MGI Symbol%3BAcc:MGI:1096338]	GO:0050798:activated T cell proliferation;GO:0007411:axon guidance;GO:0021952:central nervous system projection neuron axonogenesis;GO:0033674:positive regulation of kinase activity;GO:0032092:positive regulation of protein binding;GO:2000525:positive regulation of T cell costimulation;GO:0002456:T cell mediated immunity;GO:0007169:transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001806:type IV hypersensitivity;	GO:0009986:cell surface;GO:0005576:extracellular region;GO:0005887:integral component of plasma membrane;GO:0043005:neuron projection;GO:0043235:receptor complex;	GO:0005524:ATP binding;GO:0004714:transmembrane receptor protein tyrosine kinase activity;GO:0005005:transmembrane-ephrin receptor activity;	K05114	;ko04360 Axon guidance;
ENSMUSG00000026490	21522	41	0.10	27	0.07	76	0.16	63	0.17	51.4584189696507	2.13241573906006	1.09248873556847	0.417302224695915	2.61797965818312	0.00884520777904982	0.0432777332750319	Ups	1	179788037	179993168	+	Cdc42bpa	CDC42 binding protein kinase alpha [Source:MGI Symbol%3BAcc:MGI:2441841]	GO:0031532:actin cytoskeleton reorganization;GO:0031032:actomyosin structure organization;GO:0016477:cell migration;GO:0007010:cytoskeleton organization;GO:0035556:intracellular signal transduction;GO:0000226:microtubule cytoskeleton organization;GO:0007097:nuclear migration;GO:0018107:peptidyl-threonine phosphorylation;GO:0006468:protein phosphorylation;GO:0051056:regulation of small GTPase mediated signal transduction;	GO:0042641:actomyosin;GO:0031252:cell leading edge;GO:0005911:cell-cell junction;GO:0005737:cytoplasm;GO:0005856:cytoskeleton;GO:0030027:lamellipodium;GO:0005829:cytosol;GO:0070062:extracellular exosome;	GO:0005524:ATP binding;GO:0042802:identical protein binding;GO:0000287:magnesium ion binding;GO:0004674:protein serine/threonine kinase activity;	K16307	-
ENSMUSG00000025089	5476	5	0.05	5	0.05	15	0.13	29	0.32	13.9685616327185	4.72684912588329	2.24087881671397	0.856343452506729	2.61679914776526	0.00887585516970411	0.043399988256455	Ups	19	58224036	58444341	-	Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1 [Source:MGI Symbol%3BAcc:MGI:1100842]	GO:0009653:anatomical structure morphogenesis;GO:0016477:cell migration;GO:0007399:nervous system development;GO:0030182:neuron differentiation;GO:0031175:neuron projection development;GO:0050731:positive regulation of peptidyl-tyrosine phosphorylation;GO:0007169:transmembrane receptor protein tyrosine kinase signaling pathway;	GO:0031225:anchored component of membrane;GO:0030424:axon;GO:0009897:external side of plasma membrane;GO:0005615:extracellular space;GO:0019898:extrinsic component of membrane;GO:0005794:Golgi apparatus;GO:0005771:multivesicular body;GO:0043025:neuronal cell body;GO:0098797:plasma membrane protein complex;GO:0043235:receptor complex;	GO:0005178:integrin binding;GO:0005030:neurotrophin receptor activity;GO:0038023:signaling receptor activity;	K15015	;ko04721 Synaptic vesicle cycle;ko04723 Retrograde endocannabinoid signaling;ko04727 GABAergic synapse;ko05032 Morphine addiction;ko05033 Nicotine addiction;
ENSMUSG00000083687	366	35	4.96	37	5.75	2	0.25	14	2.28	21.8565486288343	0.242998739777011	-2.04097926304055	0.780470306883666	-2.61506330867341	0.00892109181465856	0.0435794908843499	Down	X	133452631	133452996	+	Gm15154	predicted gene 15154 [Source:MGI Symbol%3BAcc:MGI:3705516]	-	-	-	K02975	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000097488	2664	58	1.13	77	1.64	31	0.54	28	0.63	47.8364585345522	0.453823929695755	-1.13979541196087	0.436631567397088	-2.61042832692007	0.00904289189925442	0.0440902080709594	Down	12	86337535	86352780	-	4732487G21Rik	RIKEN cDNA 4732487G21 gene [Source:MGI Symbol%3BAcc:MGI:2441820]	-	-	-	-	-
ENSMUSG00000030555	8474	56	0.34	60	0.40	29	0.16	20	0.14	40.429419253891	0.436057012713237	-1.19741132093708	0.459145217931009	-2.60791417219334	0.00910957921762729	0.0443150678605215	Down	7	67297158	67412660	+	Ttc23	tetratricopeptide repeat domain 23 [Source:MGI Symbol%3BAcc:MGI:1914259]	GO:0045880:positive regulation of smoothened signaling pathway;	GO:0005929:cilium;	-	K10376	-
ENSMUSG00000026204	4249	4	0.05	1	0.01	23	0.25	11	0.15	9.54889701598418	6.96887760036008	2.80092631595207	1.07415463425425	2.60756340533471	0.00911891803536998	0.0443340168530004	Ups	1	75223671	75241146	-	Ptprn	protein tyrosine phosphatase%2C receptor type%2C N [Source:MGI Symbol%3BAcc:MGI:102765]	GO:0019221:cytokine-mediated signaling pathway;GO:1990502:dense core granule maturation;GO:0030073:insulin secretion;GO:0035773:insulin secretion involved in cellular response to glucose stimulus;GO:0001553:luteinization;GO:0035335:peptidyl-tyrosine dephosphorylation;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0000302:response to reactive oxygen species;GO:0051591:response to cAMP;GO:0043627:response to estrogen;GO:0009749:response to glucose;GO:0032868:response to insulin;GO:0019932:second-messenger-mediated signaling;	GO:0043679:axon terminus;GO:0005768:endosome;GO:0016021:integral component of membrane;GO:0016020:membrane;GO:0043025:neuronal cell body;GO:0005634:nucleus;GO:0043204:perikaryon;GO:0005886:plasma membrane;GO:0030141:secretory granule;GO:0045202:synapse;GO:0030658:transport vesicle membrane;	GO:0051020:GTPase binding;GO:0030507:spectrin binding;GO:0044389:ubiquitin-like protein ligase binding;	K07817	;ko04940 Type I diabetes mellitus;
ENSMUSG00000040841	3007	18	0.31	20	0.38	68	1.04	31	0.61	33.5166180761543	2.64290166085846	1.40212274505846	0.538949703670187	2.60158366450554	0.00927944278300232	0.0449009074264934	Ups	7	18828519	18832474	+	Six5	sine oculis-related homeobox 5 [Source:MGI Symbol%3BAcc:MGI:106220]	GO:0002088:lens development in camera-type eye;GO:0008285:negative regulation of cell proliferation;GO:1902723:negative regulation of skeletal muscle satellite cell proliferation;GO:0045892:negative regulation of transcription, DNA-templated;GO:0045944:positive regulation of transcription from RNA polymerase II promoter;GO:0006357:regulation of transcription from RNA polymerase II promoter;GO:0007286:spermatid development;	GO:0005634:nucleus;GO:0005667:transcription factor complex;	GO:0003677:DNA binding;GO:0001228:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000981:sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000978:RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043565:sequence-specific DNA binding;	K19474	-
ENSMUSG00000100615	802	11	0.71	24	1.70	2	0.11	3	0.22	9.88124503597474	0.148961400922471	-2.74698954884366	1.06294356781977	-2.5843230365259	0.00975703606819135	0.0467107059224621	Down	19	11415395	11416196	+	Gm5511	predicted gene 5511 [Source:MGI Symbol%3BAcc:MGI:3779492]	GO:0002218:activation of innate immune response;GO:0048675:axon extension;GO:0034605:cellular response to heat;GO:0098586:cellular response to virus;	GO:0016324:apical plasma membrane;GO:0044295:axonal growth cone;GO:0016323:basolateral plasma membrane;GO:0031526:brush border membrane;	GO:0005524:ATP binding;GO:0002135:CTP binding;GO:0032564:dATP binding;	K04079	;ko04141 Protein processing in endoplasmic reticulum;ko04151 PI3K-Akt signaling pathway;ko04217 Necroptosis;ko04612 Antigen processing and presentation;ko04621 NOD-like receptor signaling pathway;ko04626 Plant-pathogen interaction;ko04657 IL-17 signaling pathway;ko04659 Th17 cell differentiation;ko04914 Progesterone-mediated oocyte maturation;ko04915 Estrogen signaling pathway;ko05132 Salmonella infection;ko05200 Pathways in cancer;ko05215 Prostate cancer;ko05418 Fluid shear stress and atherosclerosis;
ENSMUSG00000089994	2635	17	0.33	18	0.39	1	0.02	4	0.09	9.84822482695887	0.152723277389793	-2.71100812695386	1.05128964636697	-2.57874519769363	0.00991598984779636	0.0473092060753296	Down	10	99015046	99020472	-	Gm16239	predicted gene 16239 [Source:MGI Symbol%3BAcc:MGI:3801746]	-	-	-	-	-
ENSMUSG00000097204	3749	51	0.71	63	0.96	23	0.28	24	0.38	39.736435507832	0.430379589519906	-1.21631843427125	0.472348332105821	-2.57504547300648	0.0100226908730012	0.0476847477029478	Down	3	96074780	96079747	-	Gm17690	predicted gene%2C 17690 [Source:MGI Symbol%3BAcc:MGI:4937324]	-	-	-	-	-
ENSMUSG00000097902	1967	22	0.58	10	0.29	2	0.05	2	0.06	8.70248399064489	0.131506296862078	-2.92679621374092	1.13685757300213	-2.57446164167428	0.0100396218163166	0.0477504841598632	Down	12	86009372	86025795	-	Gm26531	predicted gene%2C 26531 [Source:MGI Symbol%3BAcc:MGI:5477025]	-	-	-	-	-
ENSMUSG00000034413	6331	32	0.26	56	0.50	20	0.15	10	0.09	28.91111612182	0.346552399471834	-1.52885458742329	0.593911078951308	-2.57421462843032	0.0100467927954092	0.0477697738681566	Down	17	26633803	26665323	+	Neurl1b	neuralized E3 ubiquitin protein ligase 1B [Source:MGI Symbol%3BAcc:MGI:3643092]	GO:0007219:Notch signaling pathway;GO:0070086:ubiquitin-dependent endocytosis;	GO:0015629:actin cytoskeleton;GO:0005829:cytosol;GO:0005769:early endosome;	GO:0046872:metal ion binding;GO:0061630:ubiquitin protein ligase activity;	K01931	-
ENSMUSG00000085196	2558	3	0.06	0	0.00	16	0.29	12	0.28	7.73389001635808	9.76547626605063	3.28769040662245	1.27799755261325	2.57253263114611	0.0100957438354999	0.0479727722260786	Ups	19	6318825	6326635	-	Gm14963	predicted gene 14963 [Source:MGI Symbol%3BAcc:MGI:3705162]	-	-	-	-	-
ENSMUSG00000030553	1006	48	2.48	54	3.05	22	1.01	19	1.12	35.1573014713372	0.417563445126335	-1.25993267570777	0.490132820716648	-2.57059438269317	0.0101524158249721	0.0481525345685502	Down	7	67886358	67913981	-	Pgpep1l	pyroglutamyl-peptidase I-like [Source:MGI Symbol%3BAcc:MGI:1925694]	GO:0006508:proteolysis;	-	GO:0008234:cysteine-type peptidase activity;	-	-
ENSMUSG00000067344	378	14	1.92	7	1.05	36	4.38	28	4.41	21.1373717363821	3.17676131903613	1.66755669950105	0.649732634934266	2.56652753739199	0.0102722468552714	0.0485053921630206	Ups	6	145212126	145212503	+	Rps25-ps1	ribosomal protein S25%2C pseudogene 1 [Source:MGI Symbol%3BAcc:MGI:3642902]	-	GO:0022627:cytosolic small ribosomal subunit;	GO:0003735:structural constituent of ribosome;	K02975	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000063506	3876	10	0.13	19	0.28	40	0.47	39	0.60	27.1783348245565	2.83343900620153	1.50255414672212	0.585675349712301	2.56550689295737	0.0103025174333689	0.0486217813065358	Ups	14	32935983	33091891	+	Arhgap22	Rho GTPase activating protein 22 [Source:MGI Symbol%3BAcc:MGI:2443418]	GO:0090630:activation of GTPase activity;GO:0001525:angiogenesis;GO:0030154:cell differentiation;GO:0007165:signal transduction;	GO:0005737:cytoplasm;GO:0005634:nucleus;	GO:0005096:GTPase activator activity;	-	-
ENSMUSG00000058443	768	24	1.62	19	1.41	52	3.12	46	3.57	35.1918567896757	2.37914616528881	1.25044390793775	0.48745540085566	2.56524782727358	0.0103102135032842	0.0486302103535405	Ups	9	50255501	50256268	-	Rpl10-ps3	ribosomal protein L10%2C pseudogene 3 [Source:MGI Symbol%3BAcc:MGI:3704336]	GO:1990403:embryonic brain development;GO:0006417:regulation of translation;GO:0006412:translation;	GO:0022625:cytosolic large ribosomal subunit;	GO:0003735:structural constituent of ribosome;GO:0045182:translation regulator activity;	K02866	;ko03010 Ribosome;ko05171 Coronavirus disease - COVID-19;
ENSMUSG00000029491	5026	5	0.05	8	0.09	11	0.10	45	0.53	18.2638173242728	4.72930356064982	2.24162774729129	0.874353359418026	2.5637549431769	0.010354662422683	0.0487948351534792	Ups	5	108536257	108580263	+	Pde6b	phosphodiesterase 6B%2C cGMP%2C rod receptor%2C beta polypeptide [Source:MGI Symbol%3BAcc:MGI:97525]	GO:0009583:detection of light stimulus;GO:0043153:entrainment of circadian clock by photoperiod;GO:0060041:retina development in camera-type eye;GO:0007165:signal transduction;GO:0007601:visual perception;GO:1990009:retinal cell apoptotic process;	GO:0042622:photoreceptor outer segment membrane;GO:0001750:photoreceptor outer segment;GO:0005886:plasma membrane;	GO:0047555:3',5'-cyclic-GMP phosphodiesterase activity;GO:0004114:3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0046872:metal ion binding;	K13756	;ko00230 Purine metabolism;ko01100 Metabolic pathways;ko04744 Phototransduction;
ENSMUSG00000053963	7375	64	0.45	75	0.58	27	0.17	34	0.27	49.5078656935158	0.461352266823814	-1.11605934959843	0.436437279552825	-2.55720444124742	0.0105517183157988	0.0496319167651714	Down	1	180259952	180311069	-	Stum	mechanosensory transduction mediator [Source:MGI Symbol%3BAcc:MGI:2138735]	-	GO:0016021:integral component of membrane;	-	-	-