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["SEM",{"v":0.06370283574576005,"d":"0.1"},{"v":0.20293868805900728,"d":"0.2"},{"v":0.12470765814495903,"d":"0.1"},{"v":0.2068181064768427,"d":"0.2"},null,null,{"v":0.02949964689054208,"d":"0.0"},{"v":0.08668273088299264,"d":"0.1"},{"v":0.13180364183132423,"d":"0.1"},{"v":0.2345826933087775,"d":"0.2"},null,{"v":0.1262620731301017,"d":"0.1"},{"v":0.037521105172067325,"d":"0.0"},{"v":0.13096472807592124,"d":"0.1"},{"v":0.009386751893552417,"d":"0.0"},{"v":0.1197315515828825,"d":"0.1"},{"v":0.1396821789317131,"d":"0.1"},{"v":0.03754464009682339,"d":"0.0"},{"v":0.07832131113418486,"d":"0.1"},{"v":0.11637057665540342,"d":"0.1"},{"v":0.06375539192883992,"d":"0.1"},{"v":0.10143854187525451,"d":"0.1"},{"v":0.050115699469660394,"d":"0.1"},{"v":0.07407034944339502,"d":"0.1"},{"v":0.08787980427834367,"d":"0.1"}]
["EC50 (mM)",{"v":0.45498806015004806,"d":"0.5"},{"v":0.9832561390928742,"d":"1.0"},{"v":1.6672472125510625,"d":"1.7"},{"v":0.3042636003732326,"d":"0.3"},null,null,{"v":7.198632453509675,"d":"7.2"},{"v":0.7460191916152404,"d":"0.7"},{"v":0.6714288529259511,"d":"0.7"},{"v":13.905928754654413,"d":"13.9"},null,{"v":14.565766155244562,"d":"14.6"},{"v":3.9084089579240198,"d":"3.9"},{"v":0.4545691935849226,"d":"0.5"},{"v":1.0455223794228148,"d":"1.0"},{"v":2.63430870304148,"d":"2.6"},{"v":0.3950632813983231,"d":"0.4"},{"v":0.9484184633008941,"d":"0.9"},{"v":3.4766955896893332,"d":"3.5"},{"v":0.6709137099554111,"d":"0.7"},{"v":10.150793665726901,"d":"10.2"},{"v":1.699547602980046,"d":"1.7"},{"v":1.1762509846847213,"d":"1.2"},{"v":2.1355020860474356,"d":"2.1"},{"v":6.103795855585299,"d":"6.1"}]
["Fold shift",1,{"v":2.161059212781565,"d":"2"},{"v":3.664375746478336,"d":"4"},{"v":0.6687287580093665,"d":"1"},null,null,{"v":15.821585408495505,"d":"16"},{"v":1.639645645578512,"d":"2"},{"v":1.4757065332758934,"d":"1"},{"v":30.56328280365962,"d":"31"},null,{"v":32.013512948979354,"d":"32"},{"v":8.590135215053966,"d":"9"},{"v":0.9990793899844596,"d":"1"},{"v":2.297911683831918,"d":"2"},{"v":5.789841390942711,"d":"6"},{"v":0.8682937333960749,"d":"1"},{"v":2.0844908830972844,"d":"2"},{"v":7.6412897264661686,"d":"8"},{"v":1.4745743212121964,"d":"1"},{"v":22.31002207481956,"d":"22"},{"v":3.735367478477482,"d":"4"},{"v":2.5852348395621894,"d":"3"},{"v":4.69353434317195,"d":"5"},{"v":13.415287982661262,"d":"13"}]
[]
[]
["Emax",{"$nulls":8},"Basal activity",{"$nulls":9},"pEC50"]
[]
["Dunnett's multiple comparisons test","Mean Diff.","95.00% CI of diff.","Significant?","Summary","Adjusted P Value","A-?",null,null,"Dunnett's multiple comparisons test","Mean Diff.","95.00% CI of diff.","Significant?","Summary","Adjusted P Value","A-?",{"$nulls":3},"Dunnett's multiple comparisons test","Mean Diff.","95.00% CI of diff.","Significant?","Summary","Adjusted P Value","A-?"]
[]
["WT vs. K510A",35.95,"16.17 to 55.73","Yes","****",0.0001,null,"K510A",null,"WT vs. K510A",15.48,"0.8045 to 30.16","Yes","*",0.032,null,"K510A",null,null,"WT vs. K510A",0.3347,"-0.1272 to 0.7966","No","ns",0.3096,"B","K510A"]
["WT vs. K513A",29,"9.214 to 48.78","Yes","***",0.0006,null,"K513A",null,"WT vs. K513A",15.92,"1.24 to 30.59","Yes","*",0.0249,null,"K513A",null,null,"WT vs. K513A",0.564,"0.1021 to 1.026","Yes","**",0.0075,"C","K513A"]
["WT vs. M514A",6.833,"-12.95 to 26.61","No","ns",0.9868,null,"M514A",null,"WT vs. M514A",3.708,"-10.97 to 18.38","No","ns",0.9988,null,"M514A",null,null,"WT vs. M514A",-0.1748,"-0.5871 to 0.2376","No","ns",0.9202,"D","M514A"]
["WT vs. S515A",92.26,"72.48 to 112","Yes","****",0.0001,null,"S515A",null,"WT vs. S515A",24.36,"9.682 to 39.03","Yes","****",0.0001,null,"S515A",null,null,"WT vs. V578A",1.199,"0.7869 to 1.612","Yes","****",0.0001,"G","V578A"]
["WT vs. R577A",91.26,"72.9 to 109.6","Yes","****",0.0001,null,"R577A",null,"WT vs. R577A",24.86,"11.24 to 38.49","Yes","****",0.0001,null,"R577A",null,null,"WT vs. A580W",0.2148,"-0.1976 to 0.6271","No","ns",0.7421,"H","A580W"]
["WT vs. V578A",42.93,"23.15 to 62.71","Yes","****",0.0001,null,"V578A",null,"WT vs. V578A",11.28,"-4.999 to 27.56","No","ns",0.3765,null,"V578A",null,null,"WT vs. A580R",0.169,"-0.2105 to 0.5485","No","ns",0.8891,"I","A580R"]
["WT vs. A580W",24.74,"6.375 to 43.1","Yes","**",0.002,null,"A580W",null,"WT vs. A580W",9.562,"-4.061 to 23.18","No","ns",0.3594,null,"A580W",null,null,"WT vs. I581A",1.631,"1.219 to 2.044","Yes","****",0.0001,"J","I581A"]
["WT vs. A580R",22.56,"4.203 to 40.92","Yes","**",0.0067,null,"A580R",null,"WT vs. A580R",-1.474,"-15.1 to 12.15","No","ns",0.9996,null,"A580R",null,null,"WT vs. P582A",1.505,"1.043 to 1.967","Yes","****",0.0001,"L","P582A"]
["WT vs. I581A",72.6,"52.82 to 92.38","Yes","****",0.0001,null,"I581A",null,"WT vs. I581A",24.98,"10.3 to 39.65","Yes","****",0.0001,null,"I581A",null,null,"WT vs. N584A",0.934,"0.5217 to 1.346","Yes","****",0.0001,"M","N584A"]
["WT vs. I581W",89.6,"71.24 to 108","Yes","****",0.0001,null,"I581W",null,"WT vs. I581W",23.39,"10.52 to 36.26","Yes","****",0.0001,null,"I581W",null,null,"WT vs. V585A",-0.0004,"-0.3799 to 0.3791","No","ns",0.9999,"N","V585A"]
["WT vs. F582A",20.82,"-1.122 to 42.77","No","ns",0.0742,null,"F582A",null,"WT vs. P582A",0.8956,"-15.39 to 17.18","No","ns",0.9998,null,"P582A",null,null,"WT vs. K586A",0.3613,"-0.1006 to 0.8232","No","ns",0.2232,"O","K586A"]
["WT vs. N584A",51.1,"32.74 to 69.46","Yes","****",0.0001,null,"N584A",null,"WT vs. N584A",21.11,"7.489 to 34.73","Yes","***",0.0002,null,"N584A",null,null,"WT vs. M587A",0.7627,"0.4068 to 1.119","Yes","****",0.0001,"P","M587A"]
["WT vs. V585A",33.75,"16.4 to 51.09","Yes","****",0.0001,null,"V585A",null,"WT vs. V585A",2.539,"-10.33 to 15.41","No","ns",0.9991,null,"V585A",null,null,"WT vs. K588A",-0.06133,"-0.5232 to 0.4006","No","ns",0.9994,"Q","K588A"]
["WT vs. K586A",48.29,"26.34 to 70.24","Yes","****",0.0001,null,"K586A",null,"WT vs. K586A",17.62,"1.337 to 33.9","Yes","*",0.0254,null,"K586A",null,null,"WT vs. K589A",0.319,"-0.06049 to 0.6985","No","ns",0.1555,"R","K589A"]
["WT vs. M587A",52.79,"35.44 to 70.14","Yes","****",0.0001,null,"M587A",null,"WT vs. M587A",19.59,"6.716 to 32.46","Yes","***",0.0003,null,"M587A",null,null,"WT vs. K590A",0.8832,"0.5273 to 1.239","Yes","****",0.0001,"S","K590A"]
["WT vs. K588A",21.16,"-0.7889 to 43.1","No","ns",0.0661,null,"K588A",null,"WT vs. K588A",15.03,"-1.256 to 31.31","No","ns",0.0899,null,"K588A",null,null,"WT vs. I591A",0.1687,"-0.2932 to 0.6306","No","ns",0.9759,"T","I591A"]
["WT vs. K589A",21.55,"1.771 to 41.33","Yes","*",0.0238,null,"K589A",null,"WT vs. K589A",14.74,"0.06204 to 29.41","Yes","*",0.0484,null,"K589A",null,null,"WT vs. I592A",1.353,"0.9966 to 1.708","Yes","****",0.0001,"U","I592A"]
["WT vs. K590A",46.17,"27.81 to 64.53","Yes","****",0.0001,null,"K590A",null,"WT vs. K590A",20.44,"6.817 to 34.06","Yes","***",0.0004,null,"K590A",null,null,"WT vs. I592W",0.5723,"0.1104 to 1.034","Yes","**",0.0064,"V","I592W"]
["WT vs. I591A",61.25,"39.3 to 83.19","Yes","****",0.0001,null,"I591A",null,"WT vs. I591A",24.47,"9.79 to 39.14","Yes","****",0.0001,null,"I591A",null,null,"WT vs. K593A",0.4125,"0.0001766 to 0.8248","Yes","*",0.0498,"W","K593A"]
["WT vs. I592A",71.35,"54 to 88.7","Yes","****",0.0001,null,"I592A",null,"WT vs. I592A",25.01,"12.14 to 37.88","Yes","****",0.0001,null,"I592A",null,null,"WT vs. D594A",0.6715,"0.2592 to 1.084","Yes","***",0.0001,"X","D594A"]
["WT vs. I592W",41.26,"21.48 to 61.04","Yes","****",0.0001,null,"I592W",null,"WT vs. I592W",20.66,"5.98 to 35.33","Yes","**",0.0011,null,"I592W",null,null,"WT vs. L686A",1.128,"0.7481 to 1.507","Yes","****",0.0001,"Y","L686A"]
["WT vs. K593A",59.47,"39.68 to 79.25","Yes","****",0.0001,null,"K593A",null,"WT vs. K593A",22.88,"6.594 to 39.16","Yes","**",0.0011,null,"K593A"]
["WT vs. D594A",52.29,"32.51 to 72.07","Yes","****",0.0001,null,"D594A",null,"WT vs. D594A",21.94,"7.267 to 36.62","Yes","***",0.0004,null,"D594A"]
["WT vs. L686A",39.44,"19.66 to 59.22","Yes","****",0.0001,null,"L686A",null,"WT vs. L686A",23.33,"8.655 to 38.01","Yes","***",0.0002,null,"L686A"]

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["N",4,{"$nulls":3},4,{"$nulls":3},4,{"$nulls":3},4,{"$nulls":3},3]
[null,"WT-Gi",{"$nulls":3},"C351Y",{"$nulls":3},"C351L",{"$nulls":3},"C351W",{"$nulls":3},"C351A"]
[1e-09,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1]
[0.001,0.657439828,0.578991419,0.63321758,0.554631267,0.854379995,0.813004955,0.804296467,0.834197112,0.796347757,0.755614097,0.77032151,0.797353232,0.805121508,0.741072612,0.740562904,0.766762249,0.569952325,0.587629522,0.554579723]
[0.0001,0.667802814,0.593697385,0.648586145,0.567552452,0.864170839,0.876788751,0.859494575,0.885769817,0.835684569,0.829670311,0.830580906,0.853728355,0.873751573,0.816047721,0.804126724,0.814883201,0.591358056,0.621494658,0.582784116]
[1e-05,0.718398895,0.658874602,0.702366259,0.62325999,0.926380606,null,0.909218293,0.936069844,0.910432886,0.949416589,0.915584911,0.938735912,0.939346222,0.900007269,0.871232914,0.904731402,0.6512833,0.691001239,0.677517557]
[3e-06,null,0.741606313,0.779842234,0.705232385,0.977657175,null,0.928594259,0.962248521,0.968329211,1.013597807,0.947699357,0.968027096,0.978965812,0.964547646,0.884057362,0.936586247,0.744437538,0.790599571,0.782062489]
[1e-06,0.819509865,0.832054431,0.853195276,0.778660784,0.940758262,null,0.948083012,0.964941039,0.949208888,1.03077574,0.965239345,0.996788074,0.982890926,1.035359035,0.907563182,0.954341383,0.834097355,0.857332713,0.863608459]
[3e-07,0.94075794,0.941618567,0.942538141,0.883954055,0.946128418,null,0.935745994,0.971226875,0.938934851,1.03042261,0.958346691,1.000600405,0.972940244,1.005553947,0.922680942,0.968067328,0.906333389,0.932240423,0.920004087]
[1e-07,null,0.987329389,0.956942679,0.921422673,0.864542238,null,0.899878801,0.938078646,0.92478839,1.005756918,0.935912853,0.966088162,0.91796602,1.015021273,0.920128965,0.949636688,0.938511823,0.966279497,0.944279665]

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["N",4,{"$nulls":3},4,{"$nulls":3},4,{"$nulls":3},4,{"$nulls":3},4]
[null,"WT-Gi",{"$nulls":3},"G352N",{"$nulls":3},"G352M",{"$nulls":3},"G352E",{"$nulls":3},"G352W"]
[1e-09,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1]
[0.001,0.634484004,0.57155995,0.57963666,0.532432615,0.597106905,0.603389227,0.617716732,0.591679861,0.645025545,0.636929198,0.652235155,0.641930576,0.647733567,0.635221378,0.636833474,0.609784999,0.730391874,0.723409011,0.699240539,0.695559576]
[0.0001,0.653432939,0.574649539,0.59111073,0.546910823,0.632873208,0.629777432,0.625014409,0.634377333,0.687706523,0.685769134,0.686637457,0.684221106,0.676107352,0.669616043,0.664563177,0.648382622,0.803449523,0.782858431,0.774528652,0.754015812]
[1e-05,0.695525843,0.621637752,0.635758588,0.607253003,0.703059713,0.733216418,0.719396941,0.725782949,0.770574381,0.789027278,0.79062502,0.773947873,0.772385325,0.774242464,0.775918107,0.750980829,0.873598798,0.874175141,0.892613944,0.863115326]
[3e-06,null,0.71825997,0.763885865,0.675872232,0.891366712,0.835863478,0.813880762,0.810856413,0.937619723,0.900313157,0.876270604,0.870847626,0.936666861,0.89663883,0.863208128,0.845398571,0.916742532,0.930029944,0.956189269,0.925245579]
[1e-06,0.802000293,0.790408048,0.795928161,0.756020541,0.870953041,0.916403018,0.878866459,0.870757008,0.92055055,0.954166824,0.92594643,0.926177553,0.924160871,0.955993811,0.935352646,0.899202934,0.939853265,0.949242745,0.985123084,0.949873855]
[3e-07,0.924944627,0.85865661,0.863255572,0.833072214,0.962472013,0.947679213,0.911154271,0.940644442,0.963045184,0.974910226,0.945270316,0.953838956,0.954400355,0.984885606,0.965593437,0.949041321,0.947642183,0.973515106,0.988708344,0.974443128]
[1e-07,0.918355701,0.909595807,0.878085544,0.877222804,0.92408948,0.970617312,0.909730472,0.925169457,0.906383907,0.961602867,0.913909557,0.936128103,0.905320489,0.975352151,0.934981617,0.934514291,0.959596524,0.974753326,0.974217273,0.942464188]