{"text_format":"3","workbook":"xls","n_sheets":9,"sheets":["Supplementary Figure 2","Supplementary Figure 5","Supplementary Figure 7","Supplementary Figure 10","Supplementary Figure 12","Supplementary Figure 14","Supplementary Figure 15","Supplementary Figure 16","Supplementary Figure 17"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Supplementary Figure 2","index":0,"n_rows":23,"n_cols":13,"rows_kept":23,"merged":[[15,3,15,7],[15,8,15,12]],"flags":["formulas_cached_only"]}
["Supplementary Fig. 2d",null,"Week(s)","AlloNKT","AlloBCAR-NKT","Allo15BCAR-NKT","Allo15CAR19-NKT","Allo15ECAR-NKT"]
[null,null,0,1,1,1,1,1]
[null,null,2,285.75,325.15,326.75,240.63,220.65]
[null,null,3,2071.6875,3101.931,3675.9375,3027.1254,2747.0925]
[null,null,4,24860.25,36757.8824,39957.4406,46284.7474,32553.0461]
[null,null,6,3377264.96,4770437.97,4509197.17,6010074.45,4181438.77]
[]
[]
["Supplementary Fig. 2e",null,"αCD3/\nαCD28 Ab","αGC/PBMCs","aAPC"]
[null,null,90.63,120.56,92.5]
[null,null,84.63,94.56,192.98]
[null,null,130.53,153.55,94.11]
[null,null,127.54,74.62,179.05]
[null,null,64.85]
[]
["Supplementary Fig. 2e",null,"Week(s)","Non-transduced HSPC",{"$nulls":4},"Transduced HSPC"]
[null,null,0,0.0001,0.0001,0.0001,0.0001,0.0001,0.0001,0.0001,0.0001,0.0001,0.0001]
[null,null,1,0.00055,0.00025,0.00033,0.0006,0.00053,0.00353,0.00732,0.00281,0.00385,0.00642]
[null,null,2,0.00583,0.00722,0.00946,0.00723,0.00574,0.01425,0.01294,0.01035,0.00952,0.01942]
[null,null,3,0.02535,0.02752,0.03224,0.03513,0.03721,0.12942,0.18422,0.18942,0.10245,0.14221]
[null,null,4,0.07335,0.09052,0.10237,0.08375,0.09246,1.25352,1.62744,1.87295,1.92415,1.48325]
[null,null,5,0.27413,0.31954,0.36295,0.42942,0.37242,82.78397,97.30135,189.36784,132.52395,120.43526]
[null,null,6,0.76742,0.95593,2.63294,0.92841,1.04923,189.3912,216.43673,558.32352,495.34637,401.39124]

{"sheet":"Supplementary Figure 5","index":1,"n_rows":34,"n_cols":15,"rows_kept":34,"flags":["formulas_cached_only"]}
["Supplementary Fig. 5b",null,null,"AlloBCAR-NKT",null,null,"Allo15BCAR-NKT",null,null,"AlloBCAR-NKT + αGC",null,null,"Allo15BCAR-NKT + αGC"]
[null,null,0,0.89959569,0.94204852,1.15835579,0.99941246,0.9905993,1.00998825,1.02812732,1.03478905,0.93708365,1.09055877,1.09055877,0.81888247]
[null,null,3,1.49942,1.49355,2.29841,1.39935,2.42452,2.99122,5.38824,4.59966,6.39467,10.28844,6.38866,7.35632]
[null,null,5,0.68426,1.30141,1.33024,4.58825,5.28943,2.38455,16.58282,13.50377,15.93412,28.58246,20.59247,22.38357]
[null,null,7,0.114216,0.562953,0.152252,4.041552,4.999997,6.206294,45.244549,40.678013,33.630425,45.0340355,60.34514,89.287002]
[]
[]
["Supplementary Fig. 5c","AlloBCAR-NKT, - αGC","AlloBCAR-NKT, + αGC","Allo15BCAR-NKT, - αGC","Allo15BCAR-NKT, + αGC"]
[null,0.114216,45.244549,4.041552,45.0340355]
[null,0.562953,40.678013,4.999997,60.34514]
[null,0.152252,33.630425,6.206294,89.287002]
[]
["Supplementary Fig. 5d"]
["IFN-g","AlloBCAR-NKT, - αGC","AlloBCAR-NKT, + αGC","Allo15BCAR-NKT, - αGC","Allo15BCAR-NKT, + αGC"]
[null,1.241042,3084.391013,2.572301,2790.204921]
[null,0.486201,2789.294021,4.859739,3183.622942]
[null,0.114216,2567.091342,4.041552,2898.913194]
["TNF-a","AlloBCAR-NKT, - αGC","AlloBCAR-NKT, + αGC","Allo15BCAR-NKT, - αGC","Allo15BCAR-NKT, + αGC"]
[null,1.402855,318.372897,0.194255,269.79623]
[null,2.101955,298.91232,3.288253,308.129736]
[null,0.292415,286.779312,4.102884,279.891322]
["IL-4","AlloBCAR-NKT, - αGC","AlloBCAR-NKT, + αGC","Allo15BCAR-NKT, - αGC","Allo15BCAR-NKT, + αGC"]
[null,0.824194,0.430802,0.572943,0.127922]
[null,0.486201,0.213879,0.859739,1.288362]
[null,0.114216,0.25672,0.041552,0.289891]
["IL-17A","AlloBCAR-NKT, - αGC","AlloBCAR-NKT, + αGC","Allo15BCAR-NKT, - αGC","Allo15BCAR-NKT, + αGC"]
[null,2.792142,3.040828,2.572481,2.017922]
[null,2.011049,2.138789,2.859739,2.883624]
[null,2.114162,2.567128,2.041552,2.898913]
[]
["Supplementary Fig. 5e","AlloBCAR-NKT, - αGC","AlloBCAR-NKT, + αGC","Allo15BCAR-NKT, - αGC","Allo15BCAR-NKT, + αGC"]
[null,1.948253,24.482042,2.188942,746.378275]
[null,0.588325,55.932002,3.382045,518.362126]
[null,0.018842,25.249219,4.928412,898.913013]

{"sheet":"Supplementary Figure 7","index":2,"n_rows":30,"n_cols":9,"rows_kept":30,"flags":["formulas_cached_only"]}
["Supplementary Fig. 7f"]
[null,"Tumor only","NKT","NKT + IgG 1","NKT + NKG2D","NKT + DNAM-1","NKT + NKG2D + DNAM-1"]
["Allo15BCAR-NKT",1.22453,0.4422822,0.3398319,0.665471353,0.775673,0.8793527]
[null,0.98885232,0.433969713,0.43392774,0.557416801,0.791719,0.7956843]
[null,1.1004948,0.3508496,0.3922971,0.6279142,0.636048,0.9850236]
["AlloBCAR-NKT",1.00893753779,0.138863815,0.2434891266,0.43663829412,0.401927942834,0.7530027830838]
[null,1.02239946,0.23787568271,0.31334997255,0.4038864171,0.485739248128,0.763773849198]
[null,0.9739991836,0.3428247059,0.3348307,0.49938501961,0.4849357751515,0.7838937517469]
["AlloNKT",0.9547228,0.36572235,0.26177779,0.6008076,0.6860199300000001,0.9958411]
[null,0.9762551,0.2716772,0.26915597,0.6855607,0.68228827,1.0803282]
[null,1.040883,0.3616683,0.37005619,0.58241904,0.7542711,0.9105024]
[null,1.02814,0.36781172,0.3695635,0.58160398,0.58319762,0.8796028]
[]
["Supplementary Fig. 7g"]
["CD69","PBMC-T","PBMC-T","BCAR-T","BCAR-T","AlloNKT","AlloNKT","Allo15BCAR-NKT","Allo15BCAR-NKT"]
[null,"MM-FG","No MM-FG","MM-FG","No MM-FG","MM-FG","No MM-FG","MM-FG","No MM-FG"]
[null,674,1211,456,1022,1283,3756,1424,4013]
[null,575,867,754,757,1433,4221,1253,4232]
[null,633,635,788,855,1321,3822,1421,4132]
[]
["Perforin","PBMC-T","PBMC-T","BCAR-T","BCAR-T","AlloNKT","AlloNKT","Allo15BCAR-NKT","Allo15BCAR-NKT"]
[null,"MM-FG","No MM-FG","MM-FG","No MM-FG","MM-FG","No MM-FG","MM-FG","No MM-FG"]
[null,432,543,524,643,493,1849,394,2064]
[null,443,454,643,543,455,1628,203,2194]
[null,452,633,455,754,644,1671,320,2201]
["IFN-g","PBMC-T","PBMC-T","BCAR-T","BCAR-T","AlloNKT","AlloNKT","Allo15BCAR-NKT","Allo15BCAR-NKT"]
[null,"MM-FG","No MM-FG","MM-FG","No MM-FG","MM-FG","No MM-FG","MM-FG","No MM-FG"]
[null,58.6833,59.5344,15.4939,305.3855,39.2445,687.5334,19.5883,1029.3812]
[null,35.4933,23.8483,12.3355,334.2845,23.4233,789.534,40.5433,1120.3924]
[null,14.4933,20.4923,20.42445,384.49113,13.5244,895.523,24.3243,920.3134]

{"sheet":"Supplementary Figure 10","index":3,"n_rows":6,"n_cols":15,"rows_kept":6,"merged":[[0,3,0,6],[0,7,0,10],[0,11,0,14]],"flags":["formulas_cached_only"]}
["Supplementary 10c",null,null,"BCAR-T",{"$nulls":3},"AlloBCAR-NKT",{"$nulls":3},"Allo15BCAR-NKT"]
[null,null,"0:1",1.0406291,1.01572739,0.9017038,1.04193971,1.0406291,1.01572739,0.9017038,1.04193971,1.0406291,1.01572739,0.9017038,1.04193971]
[null,null,"1:1",0.83748362,0.7706422,0.98951507,0.92529489,0.30275229,0.34469201,0.21494102,0.25557012,0.20052425,0.28964613,0.30275229,0.27653997]
[null,null,"2:1",0.73918742,0.75622543,0.60943644,0.82961992,0.13368283,0.06946265,0.03145478,0.13892529,0.04325033,0.08650066,0.11140236,0.04325033]
[null,null,"5:1",0.21494102,0.58322412,0.44823067,0.31847969,0.0406291,0.06815203,0.01703801,0.01965924,0.01703801,0.02228047,0.02883355,0.01310616]
[null,null,"10:1",0.20052425,0.32110092,0.14023591,0.14809961,0.01703801,0.00131062,0.00262123,0.00524246,0,0.00655308,0.00262123,0.00262123]

{"sheet":"Supplementary Figure 12","index":4,"n_rows":10,"n_cols":8,"rows_kept":10,"flags":["formulas_cached_only"]}
["Supplementary Fig. 12e",null,"LT-HSC-NKT","LT-HSC+NKT","ST-HSC-NKT","ST-HSC+NKT","MPP-NKT","MPP+NKT"]
[null,null,1.05233105,0.94230702,0.96079315,1.15908067,0.97727273,1.14242424]
[null,null,1.0506598,1.09536576,1.03830554,0.96439838,1.02424242,1.03939394]
[null,null,0.94230702,1.09536576,0.96079315,1.03830554,1.03939394,0.96060606]
[null,null,0.95470213,1.07851398,1.04010816,1.00405588,0.95909091,1.03939394]
["Supplementary Fig. 12j",null,"LT-HSC-NKT","LT-HSC+NKT","ST-HSC-NKT","ST-HSC+NKT","MPP-NKT","MPP+NKT"]
[null,null,0.95767196,0.99823633,0.9797023,1.04104646,0.93153639,1.02641509]
[null,null,0.99647266,1.03527337,1.01939558,1.01759134,0.86684636,1.05229111]
[null,null,1.01410935,1.05291005,1.03924222,0.96346414,1.05013477,0.95525606]
[null,null,1.03174603,0.98236332,0.9616599,1.0428507,1.15148248,0.93369272]

{"sheet":"Supplementary Figure 14","index":5,"n_rows":21,"n_cols":19,"rows_kept":21,"flags":["formulas_cached_only"]}
["Supplementary Fig. 14b","NA","PBMC-T+PBMC 1","PBMC-T+PBMC 2","PBMC-T+PBMC 3","PBMC-T+PBMC 4","PBMC-T+PBMC 5","NA","PBMC-NKT+PBMC 1","PBMC-NKT+PBMC 2","PBMC-NKT+PBMC 3","PBMC-NKT+PBMC 4","PBMC-NKT+PBMC 5","NA","AlloNKT+PBMC 1","AlloNKT+PBMC 2","AlloNKT+PBMC 3","AlloNKT+PBMC 4","AlloNKT+PBMC 5"]
[null,12.53367,324.32353,164.34566,430.52456,166.43466,243.42246,4.34643,13.43235,22.54346,15.43466,4.6545,13.35235,2.43235,2.45356,12.43435,18.56654,17.45644,15.24523]
[null,2.43222,336.43486,225.43487,463.34666,186.46743,226.24634,12.34233,3.23533,17.54577,7.54577,2.43564,11.24423,4.34663,16.35574,16.4355,22.64346,2.4325,4.4534]
[null,11.53222,404.52453,253.57578,367.54577,193.5242,264.34663,5.34654,25.4346,13.52466,5.63575,8.56856,3.4135,13.23522,21.52355,16.43333,19.57553,25.3245,6.3463]
[]
["Supplementary Fig. 14e","PBMC1","PBMC-T","PBMC-NKT","AlloNKT"]
[null,2.40445,503.53565,468.35463,104.32352]
[null,3.24245,553.634346,502.45346,143.23542]
[null,1.2134524,406.54744,299.46356,153.25243]
[]
["Supplementary Fig. 14g","PBMC-T D0","PBMC-T D1","PBMC-NKT D0","PBMC-NKT D1","AlloNKT D0","AlloNKT D1"]
[null,0.96644295,0.34451902,0.96967859,0.46027896,1.05128205,0.9566075]
[null,0.99552573,0.36689038,1.02607641,0.48029109,1.04930966,0.93688363]
[null,1.03803132,0.25727069,1.004245,0.4784718,0.89940828,0.98422091]
[]
["Supplementary Fig. 14h","PBMC-T","PBMC-NKT","AlloNKT"]
[null,34.32,18.23,1.53]
[null,22.53,13.24,1.22]
[null,21.42,16.43,3.33]
[null,26.43,22.43,0.66]
[null,15.63,24.32,1.23]

{"sheet":"Supplementary Figure 15","index":6,"n_rows":77,"n_cols":29,"rows_kept":77,"merged":[[0,5,0,7]],"flags":["formulas_cached_only"]}
["Supplementary Figure 15b",null,"Vehicle",null,null,"aGC"]
[null,0,1,1,1,1,1,1]
[null,3,1.24,1.27,1.16,6.76,6.88,7.23]
[null,5,0.48,0.39,1.02,19.3,23.13,22.64]
[null,7,0.11,0.16,0.23,52.46,58.34,62.25]
["Supplementary Figure 15c"]
["IFN-r","Vehicle","αGC"]
[null,1.24,3084.25]
[null,0.49,3289.63]
[null,0.11,2567.03]
[]
["TNF-a",1.28,318.37]
[null,0.23,298.91]
[null,0.12,286.78]
[]
["IL-2",0.79,64.12]
[null,0.01,72.16]
[null,0.11,73.53]
[]
["IL-4",0.82,0.64]
[null,0.47,0.52]
[null,0.17,0.26]
[]
["IL-17A",2.79,4.04]
[null,2.01,2.13]
[null,2.11,3.57]
[]
["Supplementary Figure 15c",null,"PBMC-T",{"$nulls":3},"CAR19-T",{"$nulls":3},"Allo15CAR19-NKT",{"$nulls":4},"Raji-CD1d-FG+aGC",null,"PBMC-T",{"$nulls":3},"CAR19-T",{"$nulls":3},"Allo15CAR19-NKT"]
["Raji-FG","0:1",1.03239741,1.02051836,0.96868251,0.97840173,1.03239741,1.02051836,0.96868251,0.97840173,1.03239741,1.02051836,0.96868251,0.97840173,null,null,"0:1",0.98991173,0.93947037,0.99117276,1.07944515,0.98991173,0.93947037,0.99117276,1.07944515,0.98991173,0.93947037,0.99117276,1.07944515]
[null,"0.2:1",1.12203024,1.03347732,0.96544276,1.19114471,0.5237581,0.38444924,0.45464363,0.27213823,0.42332613,0.23866091,0.1112311,0.15010799,null,null,"0.2:1",0.99495586,1.06431274,1.02143758,1.03404792,0.37074401,0.34678436,0.22068096,0.40857503,0.01261034,0.02900378,0.00252207,0.01765448]
[null,"0.5:1",1.12203024,1.05615551,0.96652268,0.97840173,0.21382289,0.08423326,0.11231102,0.1187905,0.03131749,0.04859611,0.09611231,0.1112311,null,null,"0.5:1",1.06431274,1.07944515,1.00630517,1.06431274,0.15510719,0.21941992,0.10718789,0.20428752,0.05296343,0.00126103,0.0037831,0.00882724]
[null,"1:1",1.19006479,1.12203024,0.96436285,1.03131749,0.01403888,0.04427646,0.0161987,0.00971922,0.01079914,0.00647948,0.03671706,0.00863931,null,null,"1:1",1.07944515,1.11601513,0.95081967,0.98865069,0.08070618,0.09205549,0.02900378,0.01891551,0.02648172,0.02900378,0.00252207,0]
[null,"2:1",1.17926566,0.98272138,1.07019438,1.19006479,0.04859611,0.02483801,0.00323974,0.00215983,0,0.00107991,0.02483801,0.01295896,null,null,"2:1",1.16393443,1.15132409,1.12988651,1.0075662,0.01639344,0.00504414,0.04413619,0.0037831,0.00126103,0.00504414,0.00630517,0]
[]
["Raji-CD1d-FG",null,"PBMC-T",{"$nulls":3},"CAR19-T",{"$nulls":3},"Allo15CAR19-NKT",{"$nulls":4},"Naml6-FG",null,"PBMC-T",{"$nulls":3},"CAR19-T",{"$nulls":3},"Allo15CAR19-NKT"]
[null,"0:1",1.06105006,0.96214896,0.97069597,1.00610501,1.06105006,0.96214896,0.97069597,1.00610501,1.06105006,0.96214896,0.97069597,1.00610501,null,null,"0:1",1.03191011,0.95820225,1.0894382,0.92044944,1.03191011,0.95820225,1.0894382,0.92044944,1.03191011,0.95820225,1.0894382,0.92044944]
[null,"0.2:1",1.06105006,1.08424908,1.10622711,1.12576313,0.58119658,0.72405372,0.67521368,0.58119658,0.28083028,0.26862027,0.21367521,0.33821734,null,null,"0.2:1",1.05348315,1.11460674,1.11640449,1.10022472,0.76044944,0.5788764,0.45662921,0.63460674,0.4188764,0.31280899,0.28044944,0.36494382]
[null,"0.5:1",1.25885226,1.10744811,1.21733822,1.09279609,0.25641026,0.22588523,0.16361416,0.0952381,0.23565324,0.06837607,0.04273504,0.03418803,null,null,"0.5:1",1.12,1.16134831,1.0211236,1.12,0.37932584,0.27325843,0.11325843,0.33078652,0.0611236,0.11505618,0.00719101,0.02876404]
[null,"1:1",1.15384615,1.0964591,1.13919414,1.26251526,0.01465201,0.02930403,0.03052503,0.11477411,0.01587302,0.002442,0.00732601,0.00976801,null,null,"1:1",1.13977528,1.21168539,1.01573034,1.04988764,0.11505618,0.21573034,0.13123596,0.04853933,0.11505618,0.00179775,0.00719101,0.04134831]
[null,"2:1",0.98778999,1.17216117,1.26007326,1.19413919,0.01587302,0.004884,0.00610501,0.02319902,0,0,0.01465201,0.002442,null,null,"2:1",0.83775281,1.15775281,1.17393258,0.95640449,0.02157303,0.00719101,0.00179775,0.00719101,0.00539326,0.00539326,0.02516854,0]
[]
[]
[]
["Supplementary Figure 15j",null,"Vehicle",{"$nulls":5},"CAR19-T",{"$nulls":5},"Allo15CAR19-NKT"]
[null,3,0.001,0.00111,0.000985,0.00131,0.0018,null,0.0013,0.0011,0.00133,0.00114,0.00184,null,0.001222,0.00123,0.00131,0.00115,0.00101,0.00131]
[null,9,0.00205,0.000519,0.00261,0.0028,0.000861,null,0.000689,0.000599,0.00108,0.000737,0.00258,null,0.000752,0.000802,0.000763,0.000681,0.00068,0.000764]
[null,14,0.012,0.0372,0.0716,0.0782,0.055,null,0.00342,0.00123,0.00121,0.000123,0.00231,null,0.00128,0.0011,0.00125,0.00122,0.0011,0.00145]
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[]
[]
["Supplementary Figure 15k"]
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{"sheet":"Supplementary Figure 16","index":7,"n_rows":26,"n_cols":14,"rows_kept":26,"flags":["formulas_cached_only"]}
[]
["Supplementary Fig. 16 d"]
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{"sheet":"Supplementary Figure 17","index":8,"n_rows":26,"n_cols":12,"rows_kept":26,"flags":["formulas_cached_only"]}
[]
["Supplementary Fig. 17c","0","5","10","25","50"]
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["Supplementary Fig. 17f"]
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[]
["Supplementary Fig. 17g"]
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