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["Original Research Article"]
["Molecular dissection of transcriptional reprogramming of steviol glycosides synthesis in leaf tissue during developmental phase transitions in Stevia rebaudiana Bert"]
["Gopal Singh1,2, Gagandeep Singh1, Pradeep Singh1, Rajni Parmar1,2, Navgeet Paul1, Radhika Vashist1, Mohit Kumar Swarnkar1, Ashok Kumar3, Sanatsujat Singh3, Anil Kumar Singh1†, Sanjay Kumar1, Ram Kumar Sharma1,2* "]
["1Biotechnology Department, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, India, 2Academy of Scientific and Innovative Research, New Delhi, India, 3Agrotechnology of Medicinal, Aromatic and Commercially Important Plants, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, India, †Present address: ICAR-Indian Institute of Agricultural Biotechnology, PDU Campus, IINRG, Namkum, Ranchi, Jharkhand, India"]
[]
["Table S2 Summarization of all KEGG hits with their respective metabolic pathways and physiological processes"]
[]
["Pathway ID","Pathway name ","Pathway class","No. of transcripts ","No. of KO IDs","KO IDs"]
["ko01100","Metabolic Pathway ","Metabolism",1394,819,"K00001 K00002 K00008 K00011 K00012 K00013 K00014 K00016 K00018 K00020 K00021 K00025 K00026 K00028 K00029 K00030 K00031 K00033 K00036 K00049 K00051 K00052 K00053 K00058 K00059 K00074 K00083 K00088 K00099 K00106 K00121 K00122 K00128 K00129 K00130 K00131 K00133 K00134 K00139 K00140 K00145 K00147 K00161 K00162 K00164 K00166 K00167 K00207 K00208 K00213 K00215 K00218 K00222 K00225 K00227 K00228 K00231 K00232 K00234 K00235 K00236 K00249 K00253 K00254 K00261 K00262 K00264 K00275 K00276 K00278 K00281 K00286 K00288 K00294 K00297 K00318 K00338 K00365 K00382 K00392 K00411 K00412 K00413 K00416 K00417 K00419 K00423 K00430 K00451 K00454 K00457 K00461 K00472 K00475 K00487 K00505 K00511 K00512 K00514 K00517 K00547 K00549 K00550 K00558 K00559 K00588 K00591 K00600 K00601 K00602 K00603 K00605 K00606 K00609 K00611 K00615 K00616 K00620 K00626 K00627 K00630 K00640 K00645 K00648 K00652 K00654 K00655 K00658 K00660 K00677 K00688 K00695 K00696 K00699 K00700 K00703 K00705 K00721 K00726 K00729 K00736 K00737 K00748 K00759 K00760 K00761 K00763 K00764 K00765 K00766 K00767 K00771 K00780 K00787 K00789 K00791 K00793 K00794 K00797 K00800 K00801 K00811 K00814 K00815 K00817 K00818 K00819 K00820 K00826 K00827 K00830 K00831 K00833 K00844 K00847 K00850 K00851 K00854 K00855 K00856 K00857 K00858 K00859 K00860 K00861 K00863 K00864 K00868 K00869 K00872 K00873 K00876 K00878 K00888 K00889 K00891 K00894 K00899 K00901 K00902 K00913 K00914 K00915 K00919 K00927 K00928 K00930 K00931 K00938 K00939 K00940 K00942 K00943 K00948 K00949 K00956 K00963 K00966 K00967 K00968 K00972 K00973 K00975 K00979 K00981 K00991 K00993 K00995 K00999 K01000 K01001 K01006 K01007 K01011 K01012 K01047 K01051 K01057 K01061 K01068 K01074 K01079 K01081 K01082 K01087 K01091 K01092 K01094 K01099 K01100 K01113 K01114 K01115 K01116 K01176 K01177 K01184 K01187 K01188 K01190 K01193 K01194 K01205 K01213 K01228 K01229 K01230 K01231 K01244 K01251 K01254 K01255 K01256 K01427 K01431 K01438 K01464 K01465 K01466 K01476 K01488 K01489 K01490 K01493 K01495 K01519 K01520 K01555 K01557 K01568 K01578 K01580 K01582 K01583 K01586 K01590 K01592 K01595 K01597 K01599 K01602 K01609 K01610 K01611 K01613 K01620 K01623 K01625 K01626 K01627 K01633 K01634 K01640 K01641 K01647 K01648 K01649 K01652 K01653 K01657 K01658 K01661 K01662 K01663 K01679 K01681 K01687 K01689 K01693 K01695 K01696 K01698 K01703 K01704 K01711 K01714 K01719 K01723 K01733 K01735 K01736 K01738 K01739 K01745 K01749 K01754 K01755 K01756 K01760 K01762 K01770 K01772 K01778 K01783 K01784 K01785 K01792 K01800 K01803 K01805 K01807 K01809 K01810 K01814 K01817 K01823 K01824 K01834 K01835 K01845 K01850 K01852 K01853 K01858 K01885 K01886 K01895 K01897 K01899 K01900 K01904 K01915 K01918 K01919 K01920 K01922 K01923 K01930 K01933 K01934 K01937 K01938 K01939 K01940 K01945 K01950 K01951 K01952 K01953 K01955 K01956 K01961 K01962 K01963 K01968 K01969 K01988 K02109 K02110 K02111 K02112 K02113 K02115 K02126 K02132 K02133 K02134 K02135 K02136 K02137 K02140 K02144 K02145 K02146 K02147 K02148 K02149 K02150 K02151 K02152 K02153 K02154 K02155 K02160 K02201 K02230 K02256 K02257 K02258 K02259 K02260 K02261 K02262 K02265 K02266 K02267 K02291 K02293 K02301 K02321 K02324 K02325 K02326 K02327 K02328 K02335 K02350 K02367 K02372 K02377 K02433 K02434 K02492 K02495 K02527 K02551 K02552 K02634 K02635 K02636 K02641 K02684 K02685 K02689 K02694 K02695 K02698 K02699 K02703 K02704 K02705 K02707 K02709 K02712 K02714 K02716 K02717 K02721 K02723 K02999 K03000 K03002 K03005 K03006 K03007 K03008 K03009 K03010 K03011 K03012 K03013 K03014 K03016 K03017 K03018 K03019 K03020 K03021 K03023 K03025 K03026 K03027 K03040 K03042 K03043 K03046 K03103 K03146 K03147 K03183 K03403 K03404 K03405 K03428 K03434 K03504 K03505 K03517 K03526 K03527 K03541 K03542 K03635 K03639 K03644 K03661 K03715 K03787 K03801 K03841 K03842 K03843 K03844 K03845 K03846 K03847 K03848 K03849 K03850 K03857 K03858 K03859 K03860 K03878 K03879 K03881 K03882 K03883 K03884 K03934 K03935 K03936 K03938 K03939 K03940 K03941 K03942 K03943 K03945 K03946 K03949 K03950 K03953 K03955 K03963 K04035 K04040 K04103 K04120 K04121 K04122 K04123 K04487 K04518 K04628 K04708 K04710 K04713 K04718 K05275 K05277 K05280 K05282 K05283 K05284 K05285 K05286 K05287 K05288 K05289 K05290 K05291 K05292 K05293 K05298 K05305 K05309 K05349 K05350 K05359 K05546 K05573 K05575 K05577 K05579 K05580 K05582 K05605 K05607 K05848 K05857 K05858 K05894 K05917 K05928 K05933 K06001 K06119 K06123 K06125 K06126 K06127 K06210 K06443 K06444 K06928 K07127 K07151 K07385 K07422 K07432 K07441 K07512 K07513 K07541 K07542 K07748 K07964 K08081 K08099 K08232 K08246 K08248 K08678 K08679 K08680 K08726 K08730 K08738 K08744 K08901 K08902 K08903 K08912 K08914 K08915 K08916 K08917 K08963 K08967 K09458 K09480 K09587 K09591 K09658 K09659 K09680 K09699 K09753 K09754 K09755 K09828 K09833 K09834 K09835 K09837 K09838 K09839 K09840 K09841 K09842 K09880 K09903 K10046 K10047 K10206 K10251 K10525 K10526 K10527 K10532 K10536 K10572 K10703 K10712 K10717 K10757 K10760 K10775 K10781 K10807 K10808 K10960 K11147 K11153 K11155 K11188 K11262 K11352 K11353 K11517 K11717 K11755 K11808 K11816 K12251 K12309 K12349 K12373 K12446 K12447 K12448 K12449 K12502 K12524 K12640 K12657 K12666 K12667 K12668 K12669 K12670 K13034 K13035 K13065 K13066 K13082 K13248 K13421 K13427 K13483 K13484 K13506 K13508 K13510 K13513 K13519 K13523 K13600 K13606 K13767 K13789 K13800 K13811 K13832 K13941 K13998 K14066 K14085 K14153 K14156 K14157 K14184 K14190 K14260 K14272 K14423 K14424 K14454 K14455 K14652 K14674 K14677 K14682 K14759 K14760 K15227 K15398 K15422 K15633 K15634 K15728 K15746 K15747 K15849 K15893 K15918 K15919 K15920 K15922 K16054 K16055 K16148 K16190 K16860 K16871 K16903 K17108 K17398 K17497 K17744 K17761 K18010 K18121 K18151 K18368 K18532 K18592 K18649"]
["ko01110","Biosynthesis of secondary metabolism","Metabolism",648,352,"K00001 K00002 K00012 K00013 K00014 K00016 K00018 K00021 K00025 K00026 K00030 K00031 K00033 K00036 K00052 K00053 K00083 K00088 K00099 K00106 K00121 K00128 K00133 K00134 K00145 K00147 K00161 K00162 K00164 K00166 K00167 K00213 K00215 K00218 K00222 K00225 K00227 K00228 K00231 K00234 K00235 K00236 K00249 K00264 K00276 K00286 K00318 K00326 K00382 K00430 K00475 K00487 K00505 K00511 K00514 K00517 K00547 K00549 K00559 K00588 K00591 K00600 K00601 K00602 K00606 K00611 K00615 K00616 K00620 K00626 K00627 K00658 K00660 K00688 K00700 K00703 K00760 K00764 K00765 K00766 K00787 K00789 K00791 K00800 K00801 K00806 K00811 K00815 K00817 K00818 K00819 K00820 K00826 K00830 K00844 K00850 K00851 K00869 K00873 K00891 K00919 K00927 K00928 K00930 K00931 K00938 K00939 K00940 K00948 K00963 K00966 K00972 K00973 K00975 K00991 K01057 K01061 K01068 K01081 K01091 K01092 K01183 K01188 K01209 K01438 K01476 K01490 K01568 K01580 K01582 K01586 K01590 K01592 K01597 K01599 K01609 K01610 K01620 K01623 K01626 K01640 K01641 K01647 K01648 K01649 K01652 K01653 K01657 K01658 K01661 K01662 K01663 K01679 K01681 K01687 K01689 K01693 K01695 K01696 K01698 K01703 K01704 K01714 K01719 K01735 K01736 K01739 K01749 K01754 K01755 K01756 K01760 K01762 K01770 K01772 K01778 K01783 K01784 K01785 K01792 K01803 K01807 K01809 K01810 K01814 K01817 K01823 K01824 K01834 K01835 K01836 K01845 K01850 K01852 K01853 K01858 K01885 K01895 K01899 K01900 K01904 K01918 K01923 K01933 K01940 K01945 K01952 K01953 K01961 K01962 K01963 K02160 K02257 K02259 K02291 K02293 K02301 K02437 K02492 K02495 K02551 K02552 K03183 K03403 K03404 K03405 K03428 K03526 K03527 K03781 K03787 K03841 K04035 K04040 K04120 K04121 K04122 K04123 K04124 K04518 K05277 K05280 K05282 K05349 K05350 K05356 K05359 K05917 K05928 K05933 K06001 K06125 K06126 K06127 K06443 K06444 K07385 K07513 K08081 K08099 K08242 K08246 K08248 K08680 K09587 K09588 K09591 K09699 K09753 K09754 K09755 K09828 K09832 K09833 K09834 K09835 K09837 K09838 K09839 K09840 K09841 K09842 K10046 K10047 K10206 K10251 K10703 K10717 K10757 K10760 K10775 K10960 K11188 K11517 K11755 K11778 K11808 K11820 K11821 K12373 K12446 K12447 K12448 K12449 K12450 K12451 K12502 K12524 K12640 K13065 K13066 K13071 K13082 K13427 K13545 K13600 K13606 K13648 K13789 K13832 K14066 K14085 K14157 K14184 K14190 K14260 K14272 K14454 K14455 K14677 K14682 K14759 K14760 K14985 K15086 K15095 K15397 K15404 K15633 K15634 K15746 K15747 K15813 K15891 K15893 K15918 K15919 K16148 K17497 K17744 K18368 K18649"]
["ko01120","Microbial metabolism in diverse environment","Metabolism",276,141,"K00001 K00002 K00016 K00018 K00025 K00026 K00028 K00029 K00030 K00031 K00033 K00036 K00051 K00058 K00074 K00106 K00121 K00122 K00128 K00129 K00131 K00133 K00134 K00139 K00161 K00162 K00164 K00215 K00224 K00234 K00235 K00236 K00264 K00275 K00284 K00297 K00365 K00366 K00382 K00387 K00392 K00451 K00485 K00517 K00600 K00615 K00616 K00626 K00627 K00640 K00658 K00814 K00830 K00831 K00844 K00850 K00851 K00855 K00860 K00863 K00872 K00873 K00927 K00928 K00948 K00956 K01006 K01007 K01011 K01057 K01061 K01070 K01079 K01082 K01100 K01113 K01426 K01427 K01466 K01512 K01555 K01557 K01586 K01595 K01602 K01610 K01620 K01623 K01625 K01647 K01648 K01679 K01681 K01689 K01714 K01733 K01738 K01778 K01783 K01785 K01792 K01800 K01803 K01807 K01810 K01834 K01835 K01895 K01899 K01900 K01915 K01938 K01961 K01962 K01963 K02083 K02160 K02613 K03841 K05275 K05298 K05907 K07127 K07513 K08726 K08738 K10534 K12524 K13034 K13483 K13811 K14085 K14272 K14454 K14455 K14977 K15422 K15633 K15634 K15889 K18151"]
["ko03010","Ribosome ","Translation",252,115,"K02863 K02864 K02866 K02867 K02868 K02870 K02871 K02872 K02873 K02874 K02875 K02876 K02877 K02878 K02879 K02880 K02881 K02882 K02883 K02884 K02885 K02886 K02888 K02890 K02891 K02892 K02893 K02894 K02895 K02896 K02897 K02898 K02899 K02900 K02902 K02904 K02905 K02906 K02907 K02911 K02912 K02913 K02914 K02915 K02916 K02917 K02918 K02920 K02921 K02922 K02923 K02924 K02925 K02926 K02929 K02930 K02931 K02932 K02933 K02934 K02935 K02936 K02937 K02938 K02939 K02940 K02941 K02942 K02943 K02945 K02946 K02947 K02949 K02950 K02951 K02952 K02953 K02954 K02955 K02957 K02958 K02959 K02960 K02961 K02962 K02963 K02964 K02966 K02967 K02968 K02969 K02971 K02973 K02974 K02975 K02976 K02978 K02979 K02980 K02981 K02982 K02983 K02984 K02985 K02986 K02987 K02988 K02989 K02990 K02991 K02993 K02995 K02996 K02997 K02998"]
["ko01230","Biosynthesis of amino acids","Metabolism",199,104,"K00013 K00014 K00030 K00031 K00052 K00053 K00058 K00133 K00134 K00145 K00147 K00215 K00264 K00286 K00549 K00600 K00611 K00615 K00616 K00620 K00640 K00765 K00766 K00789 K00800 K00811 K00814 K00815 K00817 K00818 K00826 K00831 K00850 K00872 K00873 K00891 K00927 K00928 K00930 K00931 K00948 K01079 K01438 K01476 K01586 K01609 K01620 K01623 K01626 K01647 K01649 K01652 K01653 K01657 K01658 K01663 K01681 K01687 K01689 K01693 K01695 K01696 K01703 K01704 K01714 K01733 K01735 K01736 K01738 K01739 K01754 K01755 K01760 K01778 K01783 K01803 K01807 K01814 K01817 K01834 K01850 K01915 K01940 K04518 K05359 K06001 K10206 K11755 K12524 K12657 K13034 K13832 K14085 K14260 K14272 K14454 K14455 K14677 K14682 K15227 K15633 K15634 K15849 K18649"]
["ko03040","Spliceosome ","Transcription",137,98,"K03283 K06063 K09567 K10599 K11086 K11087 K11088 K11091 K11092 K11093 K11094 K11095 K11096 K11097 K11098 K11099 K11984 K12621 K12622 K12623 K12624 K12625 K12626 K12662 K12733 K12741 K12811 K12813 K12815 K12816 K12817 K12818 K12819 K12820 K12821 K12822 K12823 K12824 K12825 K12826 K12827 K12828 K12829 K12830 K12831 K12832 K12833 K12834 K12835 K12836 K12837 K12839 K12840 K12842 K12843 K12844 K12845 K12847 K12848 K12849 K12850 K12852 K12854 K12855 K12856 K12857 K12858 K12859 K12860 K12861 K12862 K12863 K12864 K12865 K12867 K12868 K12869 K12870 K12871 K12872 K12873 K12874 K12875 K12876 K12877 K12878 K12879 K12880 K12881 K12882 K12883 K12885 K12890 K12891 K12893 K12896 K12897 K12900"]
["ko00230","Purine metabolism","Nucleotide metabolism",145,92,"K00088 K00106 K00365 K00601 K00602 K00759 K00760 K00764 K00856 K00860 K00873 K00939 K00940 K00942 K00948 K00956 K00962 K01081 K01139 K01427 K01466 K01488 K01490 K01510 K01517 K01519 K01522 K01524 K01756 K01768 K01835 K01923 K01933 K01939 K01945 K01951 K01952 K02083 K02321 K02324 K02325 K02326 K02327 K02328 K02335 K02428 K02684 K02685 K02999 K03000 K03002 K03005 K03006 K03007 K03008 K03009 K03010 K03011 K03012 K03013 K03014 K03016 K03017 K03018 K03019 K03020 K03021 K03023 K03025 K03026 K03027 K03040 K03042 K03043 K03046 K03504 K03505 K03787 K06928 K07127 K10807 K10808 K11808 K13483 K13484 K13811 K14641 K14721 K14977 K18151 K18447 K18532"]
["ko03013","RNA transport","Translation",140,90,"K00784 K01164 K02516 K03113 K03231 K03236 K03237 K03238 K03239 K03240 K03241 K03242 K03243 K03245 K03246 K03247 K03248 K03250 K03251 K03252 K03253 K03254 K03257 K03259 K03260 K03262 K03537 K03538 K03539 K03680 K03754 K05019 K05749 K07562 K07936 K09291 K10577 K12160 K12875 K12876 K12877 K12878 K12879 K12880 K12881 K12882 K12883 K13114 K13126 K13130 K13137 K13151 K13171 K13174 K13175 K13176 K14004 K14288 K14289 K14290 K14291 K14292 K14293 K14294 K14297 K14298 K14299 K14300 K14301 K14303 K14304 K14306 K14307 K14308 K14309 K14310 K14311 K14312 K14313 K14315 K14318 K14319 K14320 K14321 K14324 K14325 K14326 K14327 K14328 K18213"]
["ko01200","Carbon metabolism","Metabolism",191,86,"K00018 K00025 K00026 K00028 K00029 K00030 K00031 K00033 K00036 K00051 K00058 K00121 K00122 K00131 K00134 K00140 K00161 K00162 K00164 K00234 K00235 K00236 K00249 K00281 K00297 K00382 K00600 K00605 K00615 K00616 K00626 K00627 K00640 K00658 K00814 K00830 K00831 K00844 K00850 K00851 K00855 K00863 K00873 K00927 K00948 K01006 K01007 K01057 K01070 K01079 K01100 K01455 K01595 K01602 K01610 K01623 K01625 K01647 K01679 K01681 K01689 K01738 K01754 K01783 K01803 K01807 K01810 K01834 K01895 K01899 K01900 K01938 K01961 K01962 K01963 K02160 K03841 K05298 K05605 K13034 K14272 K14454 K14455 K15633 K15634 K18121"]
["ko00190","Oxidative phosphorylation","Energy metabolism",133,81,"K00234 K00235 K00236 K00338 K00411 K00412 K00413 K00416 K00417 K00419 K01507 K01535 K02109 K02110 K02111 K02112 K02113 K02115 K02126 K02132 K02133 K02134 K02135 K02136 K02137 K02140 K02144 K02145 K02146 K02147 K02148 K02149 K02150 K02151 K02152 K02153 K02154 K02155 K02256 K02257 K02258 K02259 K02260 K02261 K02262 K02265 K02266 K02267 K02301 K03661 K03878 K03879 K03881 K03882 K03883 K03884 K03885 K03934 K03935 K03936 K03938 K03939 K03940 K03941 K03942 K03943 K03945 K03946 K03949 K03950 K03953 K03955 K03963 K05573 K05575 K05577 K05579 K05580 K05582 K11352 K11353"]
["ko04141","Protein processing","Folding, sorting and degradation",149,77,"K01228 K01230 K01456 K03094 K03237 K03283 K03347 K03868 K04079 K04426 K04523 K05546 K06689 K07151 K07342 K07765 K07953 K08054 K08057 K08288 K08653 K08852 K09481 K09485 K09486 K09487 K09490 K09503 K09517 K09518 K09523 K09540 K09561 K09562 K09580 K09584 K10084 K10085 K10088 K10575 K10578 K10597 K10601 K10636 K10661 K10666 K10839 K10956 K10976 K11718 K11863 K12275 K12666 K12667 K12668 K12669 K12670 K13249 K13250 K13525 K13719 K13989 K13993 K14001 K14003 K14004 K14005 K14006 K14007 K14009 K14011 K14012 K14015 K14016 K14018 K14026 K16196"]
["ko00240","Pyrimidine metabolism","Nucleotide metabolism",105,71,"K00207 K00254 K00384 K00609 K00761 K00857 K00876 K00940 K00943 K00962 K01081 K01240 K01431 K01464 K01465 K01489 K01493 K01510 K01519 K01520 K01937 K01955 K01956 K02321 K02324 K02325 K02326 K02327 K02328 K02335 K02684 K02685 K02999 K03000 K03002 K03005 K03006 K03007 K03008 K03009 K03010 K03011 K03012 K03013 K03014 K03016 K03017 K03018 K03019 K03020 K03021 K03023 K03025 K03026 K03027 K03040 K03042 K03043 K03046 K03504 K03505 K03787 K09903 K10807 K10808 K13421 K13800 K13998 K14641 K14721 K16329"]
["ko05016","Huntington's disease","Neurodegenerative diseases",108,65,"K00234 K00235 K00236 K00411 K00412 K00413 K00416 K00417 K00419 K02126 K02132 K02133 K02134 K02135 K02136 K02137 K02256 K02261 K02262 K02265 K02266 K02267 K03006 K03007 K03008 K03009 K03010 K03011 K03012 K03013 K03014 K03016 K03017 K03120 K03129 K03934 K03935 K03936 K03938 K03939 K03940 K03941 K03942 K03943 K03945 K03946 K03949 K03950 K03953 K03955 K03963 K04498 K04564 K04565 K04646 K05858 K05863 K06067 K08738 K11352 K11353 K11644 K11824 K11826 K15040"]
["ko05169","Epstein-Barr virus infection","Infectious diseases Viral",111,62,"K01116 K01510 K02206 K03006 K03007 K03008 K03009 K03010 K03011 K03012 K03013 K03014 K03016 K03017 K03018 K03019 K03020 K03021 K03023 K03025 K03026 K03027 K03028 K03029 K03030 K03031 K03032 K03035 K03036 K03037 K03038 K03039 K03061 K03062 K03063 K03064 K03065 K03066 K03083 K03097 K03115 K03120 K03124 K03136 K03137 K03283 K03875 K04498 K04730 K06063 K06065 K06067 K06627 K06630 K07936 K10591 K11838 K14290 K14721 K15979 K16196 K16197"]
["ko04120","Ubiquitin mediated proteolysis","Folding, sorting and degradation",101,58,"K03094 K03178 K03347 K03348 K03349 K03350 K03351 K03352 K03353 K03354 K03355 K03357 K03358 K03363 K03364 K03868 K03869 K03872 K03875 K03876 K04506 K04649 K04706 K06688 K06689 K09561 K10140 K10143 K10144 K10570 K10571 K10573 K10575 K10576 K10577 K10578 K10579 K10580 K10581 K10583 K10586 K10588 K10589 K10590 K10591 K10592 K10597 K10598 K10599 K10601 K10604 K10606 K10609 K10610 K10684 K10685 K10686 K10688                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      "]
["ko04110","Cell cycle","Cell growth and death",91,56,"K02178 K02180 K02202 K02206 K02209 K02210 K02212 K02213 K02214 K02365 K02537 K02540 K02541 K02542 K02603 K02604 K02605 K02606 K02607 K02608 K03083 K03094 K03347 K03348 K03349 K03350 K03351 K03352 K03353 K03354 K03355 K03357 K03358 K03363 K03364 K03868 K03875 K04498 K04681 K04728 K04802 K05868 K06067 K06620 K06627 K06628 K06630 K06632 K06634 K06636 K06638 K06669 K06670 K06671 K08866 K16197"]
["ko03008","Ribosome biogenesis in eukeryotes","Translation",74,55,"K01164 K03097 K03115 K03264 K03537 K03538 K03539 K03685 K06943 K07178 K07179 K07562 K07936 K11108 K11131 K11883 K12618 K12619 K12845 K13288 K14290 K14521 K14536 K14537 K14538 K14539 K14544 K14545 K14546 K14548 K14549 K14550 K14552 K14553 K14554 K14555 K14556 K14557 K14558 K14559 K14560 K14561 K14563 K14564 K14565 K14566 K14567 K14568 K14569 K14570 K14571 K14572 K14573 K14574 K18532"]
["ko05012","Parkinson's disease","Neurodegenerative diseases",79,53,"K00234 K00235 K00236 K00411 K00412 K00413 K00416 K00417 K00419 K02126 K02132 K02133 K02134 K02135 K02136 K02137 K02256 K02261 K02262 K02265 K02266 K02267 K03178 K03878 K03879 K03881 K03882 K03883 K03884 K03934 K03935 K03936 K03938 K03939 K03940 K03941 K03942 K03943 K03945 K03946 K03949 K03950 K03953 K03955 K03963 K04551 K05863 K08738 K10575 K10578 K11352 K11353 K15040"]
["ko04111","Cell cycle-yeast","Cell growth and death",72,53,"K02178 K02180 K02209 K02210 K02212 K02213 K02214 K02219 K02365 K02516 K02537 K02540 K02541 K02542 K02603 K02604 K02605 K02606 K02607 K02608 K02830 K03094 K03347 K03348 K03349 K03350 K03351 K03352 K03353 K03354 K03355 K03357 K03358 K03363 K03364 K03456 K03868 K04354 K04382 K06628 K06636 K06662 K06669 K06670 K06671 K06672 K06674 K06675 K06676 K06677 K06678 K06685 K08866"]
["ko05010","Alzheimer's disease","Neurodegenerative diseases",84,52,"K00134 K00234 K00235 K00236 K00411 K00412 K00413 K00416 K00417 K00419 K02126 K02132 K02133 K02134 K02135 K02136 K02137 K02183 K02256 K02261 K02262 K02265 K02266 K02267 K03083 K03934 K03935 K03936 K03938 K03939 K03940 K03941 K03942 K03943 K03945 K03946 K03949 K03950 K03953 K03955 K03963 K04371 K04505 K04532 K05858 K06170 K06171 K06268 K08738 K08852 K11352 K11353"]
["ko03018","RNA degradation","Folding, sorting and degradation",91,50,"K00850 K00962 K01148 K01689 K03514 K03654 K03678 K03679 K03681 K04043 K04077 K07573 K10643 K11927 K12580 K12581 K12585 K12586 K12587 K12589 K12590 K12591 K12592 K12593 K12598 K12599 K12600 K12602 K12603 K12604 K12605 K12606 K12607 K12608 K12611 K12613 K12614 K12616 K12617 K12618 K12619 K12620 K12621 K12622 K12623 K12624 K12625 K12626 K13126 K14442"]
["ko03015","mRNA survillance pathway","Translation",92,48,"K00565 K03265 K03267 K03456 K04354 K04382 K06100 K06269 K06965 K08873 K11583 K11584 K12875 K12876 K12877 K12881 K12882 K12883 K13114 K13126 K13171 K13917 K14294 K14324 K14325 K14326 K14327 K14328 K14376 K14396 K14397 K14398 K14399 K14400 K14401 K14402 K14403 K14404 K14405 K14406 K14407 K14408 K14409 K14411 K14416 K14962 K15542 K15544"]
["ko04932","Non-alcoholic fatty liver disease (NAFLD)","Lipid metabolism",73,44,"K00234 K00235 K00236 K00411 K00412 K00413 K00416 K00417 K00419 K02256 K02261 K02262 K02265 K02266 K02267 K03083 K03237 K03934 K03935 K03936 K03938 K03939 K03940 K03941 K03942 K03943 K03945 K03946 K03949 K03950 K03953 K03955 K03963 K04392 K04426 K07198 K07199 K07200 K07297 K08738 K08822 K08852 K11352 K11353"]
["ko04113","Meiosis- yeast","Cell growth and death",55,43,"K01768 K02178 K02209 K02210 K02212 K02213 K02214 K02365 K02537 K02540 K02541 K02542 K02603 K02604 K02605 K02606 K02607 K02608 K02830 K03348 K03349 K03350 K03351 K03352 K03353 K03354 K03355 K03357 K03358 K03363 K03456 K04382 K06269 K06628 K06636 K06662 K06669 K06671 K08139 K10872 K10878 K11584 K12767"]
["ko04144","Endocytosis ","Transport and catabolism",85,40,"K00889 K01115 K01528 K03283 K04646 K07897 K07904 K07937 K10591 K11824 K11826 K11866 K11981 K12182 K12183 K12184 K12185 K12188 K12190 K12191 K12192 K12193 K12194 K12195 K12196 K12197 K12198 K12199 K12200 K12471 K12478 K12479 K12483 K12486 K12489 K12492 K12493 K15053 K18442 K18443"]
["ko05166","HTLV-I infection","Infectious diseases Viral",68,40,"K00787 K02180 K02324 K02325 K02326 K02327 K02328 K02537 K03083 K03120 K03348 K03349 K03350 K03351 K03352 K03353 K03354 K03355 K03357 K03358 K03363 K03504 K03505 K04498 K04728 K04802 K05863 K06062 K06268 K06620 K07936 K08054 K08057 K08874 K11126 K14290 K15040 K15304 K15305 K15306"]
["ko05203","Viral carcinogenesis","Cancers Overview",90,39,"K00873 K02146 K02206 K03062 K03120 K03122 K03124 K03136 K03137 K03141 K03142 K03143 K03144 K03363 K03875 K04371 K04392 K04498 K04681 K06062 K06063 K06067 K06627 K06630 K06638 K10610 K10691 K11252 K11254 K11407 K11418 K11594 K11643 K11838 K15305 K15306 K15979 K16175 K16197"]
["ko00564","Glycerophospholipid metabolism","Lipid metabolism",72,39,"K00006 K00057 K00111 K00550 K00630 K00655 K00894 K00901 K00967 K00968 K00981 K00993 K00995 K00999 K01047 K01094 K01114 K01115 K01126 K01517 K01613 K05929 K06123 K06130 K08730 K08744 K13506 K13508 K13510 K13511 K13513 K13519 K13523 K14156 K14674 K15728 K16860 K17830 K18693"]
["ko00500","Starch and sucrose metabolism","Carbohydrate metabolism",122,38,"K00012 K00688 K00695 K00696 K00699 K00700 K00703 K00705 K00706 K00844 K00847 K00963 K00975 K01051 K01087 K01176 K01177 K01184 K01187 K01188 K01193 K01194 K01210 K01212 K01213 K01810 K01835 K01838 K05349 K05350 K08678 K08679 K13648 K15920 K15922 K16055 K16148 K18447"]
["ko00330","Arginine and proline metabolism","Amino acid metabolism",59,38,"K00128 K00145 K00147 K00261 K00262 K00286 K00294 K00318 K00472 K00611 K00620 K00797 K00811 K00818 K00819 K00930 K00931 K01259 K01426 K01427 K01438 K01476 K01583 K01611 K01755 K01915 K01940 K10536 K12251 K12259 K12657 K13427 K14085 K14454 K14455 K14677 K14682 K17839"]
["ko04075","Plant hormone signal transduction","Signal transduction",95,37,"K12126 K13415 K13422 K13449 K13463 K13464 K13946 K14431 K14432 K14484 K14485 K14486 K14487 K14488 K14489 K14490 K14491 K14492 K14493 K14494 K14495 K14496 K14497 K14498 K14499 K14500 K14503 K14505 K14506 K14508 K14509 K14510 K14512 K14513 K14514 K14515 K14516"]
["ko04146","Peroxisome ","Transport and catabolism",66,37,"K00031 K00106 K00232 K00308 K00830 K00869 K01578 K01640 K01897 K03426 K03781 K04564 K04565 K06664 K07513 K08726 K11147 K11187 K11517 K12261 K12663 K13237 K13335 K13336 K13337 K13338 K13339 K13341 K13342 K13343 K13344 K13345 K13346 K13347 K13348 K13354 K13356"]
["ko03420","Nucleotide excision repair","Replication and repair",51,37,"K02202 K02324 K02325 K02326 K02327 K02328 K02335 K03141 K03142 K03143 K03144 K03504 K03505 K03868 K04802 K06634 K07466 K10140 K10570 K10609 K10610 K10739 K10740 K10747 K10754 K10755 K10756 K10838 K10839 K10841 K10842 K10843 K10844 K10845 K10846 K10848 K10849"]
["ko00520","Amino sugar and nucleotide sugar metabolism","Carbohydrate metabolism",85,35,"K00012 K00326 K00820 K00844 K00847 K00963 K00966 K00972 K00975 K01183 K01209 K01711 K01784 K01809 K01810 K01835 K01836 K02377 K05305 K06118 K08678 K08679 K10046 K12373 K12446 K12447 K12448 K12449 K12450 K12451 K13648 K15920 K16190 K17497 K18677"]
["ko00195","Photosynthesis","Energy metabolism",53,34,"K02109 K02110 K02111 K02112 K02113 K02115 K02634 K02635 K02636 K02638 K02639 K02641 K02689 K02694 K02695 K02698 K02699 K02703 K02704 K02705 K02707 K02709 K02712 K02714 K02716 K02717 K02721 K02723 K03541 K03542 K08901 K08902 K08903 K14332"]
["ko00270","Cysteine and methionine metabolism","Amino acid metabolism",60,33,"K00016 K00025 K00026 K00133 K00547 K00549 K00558 K00640 K00789 K00797 K00811 K00815 K00899 K00928 K01011 K01244 K01251 K01611 K01738 K01739 K01760 K01761 K01762 K05933 K08963 K08967 K09880 K12524 K13034 K14454 K14455 K16054 K17398"]
["ko00260","Glycine, serine and threonine metabolism","Amino acid metabolism",57,33,"K00018 K00049 K00058 K00130 K00133 K00276 K00281 K00382 K00600 K00605 K00827 K00830 K00831 K00872 K00928 K01079 K01620 K01695 K01696 K01733 K01754 K01834 K02437 K06001 K12235 K12524 K14085 K14272 K15633 K15634 K15893 K15918 K15919"]
["ko00010","Glycolysis/ gluconeogenesis","Carbohydrate metabolism",89,32,"K00001 K00002 K00016 K00121 K00128 K00129 K00131 K00134 K00161 K00162 K00382 K00627 K00844 K00850 K00873 K00927 K01568 K01610 K01623 K01689 K01785 K01792 K01803 K01810 K01834 K01835 K01895 K03103 K03841 K14085 K15633 K15634"]
["ko04114","Oocyte meiosis","Cell growth and death",54,32,"K02178 K02183 K02206 K02365 K02537 K03094 K03347 K03348 K03349 K03350 K03351 K03352 K03353 K03354 K03355 K03357 K03358 K03363 K03456 K03868 K04368 K04371 K04373 K04382 K04515 K06268 K06269 K06630 K06636 K06669 K11584 K16197"]
["ko03050","Proteasome ","Folding, sorting and degradation",53,32,"K02725 K02726 K02727 K02728 K02729 K02730 K02731 K02732 K02734 K02736 K02737 K02738 K02739 K03028 K03029 K03030 K03031 K03032 K03035 K03036 K03037 K03038 K03039 K03061 K03062 K03063 K03064 K03065 K03066 K06699 K06700 K11599"]
["ko00620","Pyruvate metabolism","Carbohydrate metabolism",68,31,"K00016 K00025 K00026 K00028 K00029 K00049 K00051 K00102 K00128 K00161 K00162 K00382 K00626 K00627 K00873 K01006 K01007 K01069 K01512 K01595 K01610 K01649 K01679 K01759 K01895 K01961 K01962 K01963 K02160 K11262 K14085"]
["ko04145","Phagosome","Transport and catabolism",66,31,"K00914 K00921 K01365 K02144 K02145 K02146 K02147 K02148 K02149 K02150 K02151 K02152 K02153 K02154 K02155 K03661 K04392 K07342 K07374 K07375 K07897 K08008 K08054 K08057 K08488 K08492 K08517 K09481 K10956 K12182 K12478"]
["ko00860","Porphyrin and chlorophyll metabolism","Metabolism of cofactors and vitamins",53,31,"K00218 K00228 K00231 K00510 K00699 K01599 K01698 K01719 K01749 K01772 K01845 K01885 K02230 K02257 K02259 K02301 K02492 K02495 K03403 K03404 K03405 K03428 K04035 K04040 K08099 K10960 K13071 K13545 K13600 K13606 K18010"]
["ko03030","DNA replication ","Replication and repair",40,31,"K02209 K02210 K02212 K02321 K02324 K02325 K02326 K02327 K02328 K02335 K02540 K02541 K02542 K02684 K02685 K03111 K03504 K03505 K04799 K04802 K07466 K10739 K10740 K10742 K10743 K10744 K10745 K10747 K10754 K10755 K10756"]
["ko00510","N-Glycan biosynthesis","Glycan biosynthesis and metabolism",38,31,"K00721 K00726 K00729 K00736 K00737 K00902 K01001 K01228 K01230 K01231 K03842 K03843 K03844 K03845 K03846 K03847 K03848 K03849 K03850 K05546 K07151 K07252 K07432 K07441 K09658 K09659 K12666 K12667 K12668 K12669 K12670"]
["ko00900","Terpenoid backbone biosynthesis","Metabolism of terpenoids and polyketides",48,30,"K00021 K00099 K00587 K00626 K00787 K00806 K00869 K00919 K00938 K00991 K01597 K01641 K01662 K01770 K01823 K03526 K03527 K05356 K05906 K05954 K05955 K06013 K08658 K10960 K11778 K13789 K14066 K15889 K15891 K15892"]
["ko01210","2-Oxocarboxylic acid metabolism","Metabolism",43,30,"K00030 K00031 K00052 K00053 K00133 K00145 K00620 K00811 K00814 K00818 K00826 K00928 K00930 K01438 K01647 K01649 K01652 K01653 K01681 K01687 K01703 K01704 K11820 K11821 K14260 K14272 K14454 K14455 K14677 K14682"]
["ko01212","Fatty acid metabolism","Lipid metabolism",66,29,"K00059 K00208 K00232 K00249 K00507 K00626 K00645 K00648 K01074 K01897 K01961 K01962 K01963 K02160 K02372 K03921 K07512 K07513 K09458 K10224 K10251 K10255 K10256 K10257 K10527 K10703 K10781 K11262 K13767"]
["ko05200","Pathways in cancer","Cancers Overview",58,29,"K01110 K01116 K01679 K02206 K02219 K03083 K03868 K03872 K03875 K04079 K04368 K04371 K04392 K04482 K04498 K04536 K05858 K06067 K06228 K06620 K07203 K08734 K08735 K08736 K08737 K08738 K08775 K09291 K09487"]
["ko04142","Lysosome","Transport and catabolism",45,29,"K01074 K01205 K01365 K01366 K01369 K01373 K01444 K02144 K02146 K02154 K02155 K03661 K04646 K10532 K12309 K12373 K12382 K12385 K12386 K12391 K12392 K12393 K12396 K12397 K12398 K12399 K12400 K12402 K12403"]
["ko00250","Alanine, aspartate and glutamate metabolism","Amino acid metabolism",35,29,"K00139 K00261 K00262 K00264 K00278 K00294 K00609 K00764 K00811 K00814 K00820 K00827 K00830 K01580 K01755 K01756 K01915 K01939 K01940 K01953 K01955 K01956 K13566 K14260 K14272 K14454 K14455 K16871 K17761"]
["ko05168","Herpes simplex infection","Infectious diseases Viral",51,28,"K02206 K03006 K03094 K03097 K03115 K03120 K03127 K03129 K03130 K03131 K03133 K03134 K03237 K03347 K03875 K04498 K06269 K08738 K11674 K11838 K12881 K12890 K12891 K12893 K12896 K14840 K15414 K16196"]
["ko03020","RNA polymerase","Transcription",39,28,"K02999 K03000 K03002 K03005 K03006 K03007 K03008 K03009 K03010 K03011 K03012 K03013 K03014 K03016 K03017 K03018 K03019 K03020 K03021 K03023 K03025 K03026 K03027 K03040 K03042 K03043 K03046 K14721"]
["ko03460","Fanconi anemia pathway","Replication and repair",38,28,"K02350 K03165 K03509 K03511 K03515 K04482 K07466 K08734 K08775 K08991 K10606 K10739 K10740 K10848 K10849 K10858 K10882 K10891 K10896 K10901 K10990 K11137 K13960 K15078 K15360 K15361 K15362 K15363"]
["ko03022","Basal transcription factors","Transcription",36,28,"K02202 K03120 K03122 K03124 K03125 K03126 K03127 K03128 K03129 K03130 K03131 K03132 K03133 K03134 K03136 K03137 K03138 K03139 K03141 K03142 K03143 K03144 K06634 K10842 K10843 K10844 K10845 K14649"]
["ko04626","Plant-pathogen interaction","Environmental adaptation",69,25,"K00864 K02183 K04079 K04368 K05391 K09487 K12795 K13412 K13413 K13414 K13420 K13422 K13424 K13425 K13427 K13429 K13430 K13447 K13448 K13449 K13456 K13458 K13462 K13463 K13464"]
["ko04152","AMPK signaling pathway","Signal transduction",54,25,"K00021 K00507 K00850 K01103 K01578 K03234 K03456 K03841 K04354 K04382 K04688 K06276 K06627 K07198 K07199 K07200 K07203 K07204 K07297 K07359 K07877 K08272 K11262 K11583 K11584"]
["ko00561","Glycerolipid metabolism","Lipid metabolism",52,25,"K00002 K00011 K00128 K00630 K00655 K00679 K00863 K00864 K00901 K03715 K06118 K06119 K07407 K09480 K11155 K13506 K13508 K13513 K13519 K13523 K14085 K14674 K15728 K15918 K18693"]
["ko00970","Aminoacyl-tRNA biosynthesis","Translation",49,25,"K00604 K01866 K01867 K01868 K01869 K01870 K01872 K01873 K01874 K01875 K01876 K01880 K01881 K01883 K01885 K01886 K01887 K01889 K01890 K01892 K01893 K02433 K02434 K04567 K14164"]
["ko03060","Protein export","Folding, sorting and degradation",42,25,"K03070 K03100 K03104 K03105 K03106 K03107 K03108 K03109 K03116 K03118 K03217 K07342 K09481 K09490 K09540 K09647 K09648 K10956 K12272 K12275 K12946 K12947 K12948 K13280 K13431"]
["ko00400","Phenylalanine, tyrosine and tryptophan biosynthesis","Amino acid metabolism",41,25,"K00014 K00766 K00800 K00811 K00815 K00817 K00891 K01609 K01626 K01657 K01658 K01695 K01696 K01735 K01736 K01817 K01850 K04518 K05359 K06001 K13832 K14454 K14455 K15227 K15849"]
["ko03410","Base excision repair","Replication and repair",39,25,"K01142 K01246 K01247 K02324 K02325 K02326 K02327 K02328 K02335 K03504 K03505 K03512 K03575 K03648 K03660 K04799 K04802 K10563 K10747 K10772 K10773 K10798 K10801 K10802 K10803"]
["ko03440","Homologous recombination","Replication and repair",35,25,"K02327 K02328 K02335 K03111 K03165 K03504 K03505 K03553 K03655 K04482 K07466 K08775 K08991 K10739 K10740 K10865 K10866 K10867 K10869 K10871 K10875 K10879 K10880 K10882 K10901"]
["ko00710","Carbon fixation in photosynthetic organisms","Energy metabolism",50,24,"K00025 K00026 K00028 K00029 K00051 K00134 K00615 K00814 K00855 K00927 K01006 K01100 K01595 K01602 K01610 K01623 K01783 K01803 K01807 K03841 K05298 K14272 K14454 K14455"]
["ko00630","Glyoxylate and dicarboxylate metabolism","Carbohydrate metabolism",42,24,"K00018 K00025 K00026 K00049 K00122 K00284 K00600 K00626 K00830 K01091 K01433 K01455 K01602 K01625 K01647 K01681 K01915 K02437 K03781 K11517 K14272 K15893 K15918 K15919"]
["ko00562","Inositol phosphate metabolism","Carbohydrate metabolism",44,23,"K00140 K00469 K00888 K00889 K00913 K00914 K00915 K00921 K00999 K01092 K01099 K01110 K01114 K01116 K01803 K01858 K03103 K05857 K05858 K10047 K10572 K15422 K18649"]
["ko04151","PI3K-Akt signaling pathway","Signal transduction",48,23,"K01110 K02206 K02991 K03083 K03259 K03456 K04079 K04354 K04368 K04371 K04382 K04392 K04536 K04688 K06276 K06630 K07198 K07203 K07204 K09487 K11583 K11584 K16197"]
["ko00513","Various type of N-glycane biosynthesis","Glycan biosynthesis and metabolism",27,22,"K00726 K00736 K00753 K01230 K01231 K03714 K03842 K03843 K03844 K03845 K03846 K03847 K07151 K07432 K07441 K12666 K12667 K12668 K12669 K12670 K14412 K14413"]
["ko04721","Synaptic vesicle cycle","Nervous system",53,21,"K01528 K02144 K02145 K02146 K02147 K02148 K02149 K02150 K02151 K02152 K02153 K02154 K02155 K03661 K04646 K06027 K08486 K11824 K11826 K15015 K15292"]
["ko04914","Progesterone-mediated oocyte maturation","Endocrine system",36,21,"K02178 K02206 K02537 K03348 K03349 K03350 K03351 K03352 K03353 K03354 K03355 K03357 K03358 K03364 K04079 K04368 K04371 K04373 K05868 K06627 K06638"]
["ko03430","Mismatch repair","Replication and repair",32,21,"K02327 K02328 K03111 K03504 K03505 K04802 K07456 K07466 K08734 K08735 K08736 K08737 K08739 K10739 K10740 K10746 K10747 K10754 K10755 K10756 K10858"]
["ko05152","Tuberculosis","Infectious diseases Bacterial",53,20,"K00914 K02144 K02146 K02154 K02155 K02183 K03661 K04043 K04077 K04371 K04498 K04515 K04718 K04730 K04733 K06268 K07897 K08064 K08738 K12478"]
["ko00680","Methane metabolism","Energy metabolism",49,20,"K00018 K00058 K00121 K00122 K00600 K00830 K00831 K00850 K00863 K01007 K01070 K01079 K01595 K01623 K01689 K01834 K01895 K03841 K15633 K15634"]
["ko04070","Phosphatidylinositol signaling system","Signal transduction",45,20,"K00888 K00889 K00901 K00913 K00914 K00915 K00921 K00981 K00999 K01092 K01099 K01110 K01116 K02183 K05857 K05858 K10047 K10572 K15422 K18649"]
["ko00020","Citrate cycle (TCA cycle)","Carbohydrate metabolism",44,20,"K00025 K00026 K00030 K00031 K00161 K00162 K00164 K00234 K00235 K00236 K00382 K00627 K00658 K01610 K01647 K01648 K01679 K01681 K01899 K01900"]
["ko00280","Valine, leucine and isoleucine degradation","Amino acid metabolism",35,20,"K00020 K00128 K00140 K00166 K00167 K00249 K00253 K00382 K00626 K00826 K01640 K01641 K01968 K01969 K05605 K05607 K07513 K09699 K14085 K18660"]
["ko00130","Ubiquinone and other terpenoid-quinone biosynthesis","Metabolism of cofactors and vitamins",30,20,"K00457 K00487 K00591 K00815 K01661 K01904 K02551 K02552 K03183 K05928 K06125 K06126 K06127 K08680 K09833 K09834 K12501 K12502 K14759 K14760"]
["ko04712","Circadian rhythm-plants","Environmental adaptation",27,20,"K00660 K03097 K03115 K10143 K12115 K12118 K12119 K12120 K12121 K12124 K12125 K12126 K12127 K12129 K12130 K12133 K16166 K16222 K16223 K16241"]
["ko00563","Glycosylphosphatidylinositol(GPI)-anchor biosynthesis","Glycan biosynthesis and metabolism",24,20,"K03434 K03857 K03858 K03859 K03860 K05283 K05284 K05285 K05286 K05287 K05288 K05289 K05290 K05291 K05292 K05293 K05310 K07541 K07542 K09658"]
["ko04910","Insulin signaling pathway","Endocrine system",41,19,"K01116 K02144 K02145 K02146 K02147 K02148 K02149 K02150 K02151 K02152 K02153 K02154 K02155 K03661 K07342 K07937 K09481 K10949 K10956"]
["ko05110","Vibrio cholerae infection","Infectious diseases Bacterial",41,19,"K01116 K02144 K02145 K02146 K02147 K02148 K02149 K02150 K02151 K02152 K02153 K02154 K02155 K03661 K07342 K07937 K09481 K10949 K10956"]
["ko00940","Phenylpropanoid biosynthesis","Biosynthesis of other secondary metabolites",61,18,"K00083 K00430 K00487 K00588 K01188 K01904 K05349 K05350 K09753 K09754 K09755 K10775 K11188 K12355 K12356 K13065 K13066 K18368"]
["ko00360","Phenylalanine metabolsim","Amino acid metabolism",55,18,"K00074 K00129 K00276 K00430 K00457 K00487 K00588 K00811 K00815 K00817 K01426 K01904 K02613 K10775 K11188 K14454 K14455 K15849"]
["ko00051","Fructose and mannose metabolism","Carbohydrate metabolism",41,18,"K00008 K00011 K00844 K00847 K00850 K00895 K00966 K01103 K01623 K01711 K01803 K01805 K01809 K02377 K03841 K05305 K17497 K18447"]
["ko04066","HIF-1 signaling pathway","Signal transduction",41,18,"K00134 K00161 K00162 K00844 K01103 K01116 K01689 K02991 K03259 K03868 K03872 K04368 K04371 K04498 K04515 K04688 K07203 K08008"]
["ko04919","Thyroid hormone signaling pathway","Signal transduction",36,18,"K01114 K01116 K03083 K04368 K04371 K04498 K04650 K05857 K05858 K06062 K06067 K06276 K07203 K11644 K15133 K15156 K15164 K15170"]
["ko00100","Steroid biosynthesis","Lipid metabolism",22,18,"K00213 K00222 K00227 K00511 K00559 K00801 K01824 K01852 K01853 K05917 K07748 K08242 K08246 K09828 K09832 K14423 K14424 K14674"]
["ko04810","Regulation of actin cytoskeleton","Cell motility",42,17,"K00889 K00921 K04368 K04371 K04392 K05745 K05749 K05752 K05754 K05755 K05756 K05757 K05758 K05759 K05765 K05766 K06269"]
["ko00030","Pentose Phosphate pathway ","Carbohydrate metabolism",38,17,"K00033 K00036 K00131 K00615 K00616 K00850 K00851 K00852 K00948 K01057 K01623 K01625 K01783 K01807 K01810 K01835 K03841"]
["ko05164","Influenza A","Infectious diseases Viral",37,17,"K00787 K03083 K03237 K03283 K04368 K04371 K04498 K04733 K08738 K09523 K14290 K14297 K14298 K14396 K14404 K15044 K16196"]
["ko04068","FoxO signalling pathway","Signal transduction",34,17,"K01110 K02206 K03781 K03875 K04368 K04371 K04498 K04564 K04728 K05868 K06276 K07198 K07199 K07200 K08341 K11434 K11838"]
["ko00350","Tyrosine metabolism ","Amino acid metabolism",23,17,"K00001 K00121 K00129 K00276 K00451 K00457 K00505 K00811 K00815 K00817 K01555 K01557 K01592 K01800 K14454 K14455 K15849"]
["ko00906","Carotenoid biosynthesis ","Biosynthesis of other secondary metabolites",22,17,"K00514 K02291 K02293 K06443 K06444 K09835 K09837 K09838 K09839 K09840 K09841 K09842 K09843 K15746 K15747 K17911 K17912"]
["ko00040","Pentose and glucoronate interconversion","Carbohydrate metabolism",55,16,"K00002 K00008 K00011 K00012 K00128 K00699 K00854 K00963 K01051 K01184 K01213 K01728 K01783 K01805 K12447 K16190"]
["ko00480","Glutathione metabolism","Metabolism of other amino acids",47,16,"K00031 K00033 K00036 K00383 K00432 K00434 K00797 K00799 K01255 K01256 K01469 K01919 K01920 K10807 K10808 K18592"]
["ko00053","Ascorbate and aldarate metabolism","Carbohydrate metabolism",40,16,"K00012 K00128 K00225 K00423 K00434 K00469 K00699 K08232 K10046 K10047 K12447 K14085 K14190 K16190 K17744 K18649"]
["ko04310","Wnt signalling pathway","Signal transduction",38,16,"K03083 K03094 K03097 K03115 K03347 K03868 K04392 K04498 K04499 K04505 K04506 K04507 K04508 K04515 K05858 K06268"]
["ko05120","Epithelial cell signalling in Helicobacter pylori infection","Infectious diseases Bacterial",31,16,"K01116 K02144 K02145 K02146 K02147 K02148 K02149 K02150 K02151 K02152 K02153 K02154 K02155 K03661 K04392 K05728"]
["ko04130","SNARE interections un vesicular trtansport","Folding, sorting and degradation",28,16,"K08486 K08488 K08489 K08490 K08492 K08493 K08495 K08496 K08497 K08503 K08504 K08505 K08506 K08515 K08516 K08517"]
["ko00410","beta-Alanine metabolism","Metabolism of other amino acids",26,16,"K00128 K00129 K00140 K00207 K00249 K00276 K00797 K01431 K01464 K01578 K01580 K01918 K05605 K12259 K14085 K17839"]
["ko00052","Galactose metabolism","Carbohydrate metabolism",22,16,"K00011 K00844 K00850 K00963 K01187 K01190 K01193 K01229 K01784 K01785 K01835 K06617 K07407 K12309 K12447 K15922"]
["ko04722","Neurotrophin signalling pathway","Nervous system",36,15,"K01116 K02183 K03083 K04368 K04371 K04373 K04392 K04426 K04505 K04515 K04730 K04733 K06276 K06630 K12462"]
["ko05206","MicroRNAs in cancer ","Cancers Overview",34,15,"K00558 K01110 K01116 K04368 K04498 K04728 K05658 K06620 K07203 K07204 K07996 K10577 K11430 K11592 K17398"]
["ko00061","Fatty acid biosynthesis ","Lipid metabolism",32,15,"K00059 K00208 K00645 K00648 K01897 K01961 K01962 K01963 K02160 K02372 K03921 K09458 K10781 K10782 K11262"]
["ko00920","Sulfur metabolism","Energy metabolism",30,15,"K00387 K00392 K00640 K00860 K00956 K01011 K01082 K01738 K01739 K05907 K08738 K13034 K13811 K15422 K17725"]
["ko00720","Carbon fixation in prokaryotes","Energy metabolism",23,15,"K00031 K00297 K00626 K01006 K01007 K01595 K01648 K01679 K01681 K01895 K01938 K01961 K01962 K01963 K02160"]
["ko00770","Pantothenate and CoA biosynthesis ","Metabolism of cofactors and vitamins",21,15,"K00053 K00207 K00606 K00826 K00859 K01431 K01464 K01652 K01653 K01687 K01918 K01922 K02201 K06133 K09680"]
["ko00600","Sphingolipid metabolism","Lipid metabolism",19,15,"K00654 K01190 K01634 K04628 K04708 K04710 K04711 K04713 K04715 K04718 K05848 K07407 K12309 K12349 K17108"]
["ko05034","Alcoholism","Substance dependence",59,14,"K02183 K04368 K04371 K04536 K06067 K06269 K07359 K11251 K11252 K11253 K11254 K11303 K11407 K11418"]
["ko04666","Fc gamma R-mediated phagocytosis","Immune system",39,14,"K00889 K01115 K01116 K04368 K04371 K04392 K04688 K04718 K05754 K05755 K05756 K05757 K05758 K05765"]
["ko04921","Oxytocin signalling pathway","Signal transduction",27,14,"K02183 K03234 K04368 K04371 K04454 K04515 K05858 K06268 K06269 K07198 K07199 K07200 K07359 K08794"]
["ko05323","Rheumatoid arthritis","Immune diseases",27,14,"K01365 K02144 K02145 K02146 K02147 K02148 K02149 K02150 K02151 K02152 K02153 K02154 K02155 K03661"]
["ko05205","Proteoglycans in cancer","Cancers Overview",23,14,"K01116 K01365 K02991 K03685 K04368 K04371 K04392 K04515 K04688 K06269 K06276 K07203 K07964 K12823"]
["ko00340","Histidine metabolism","Amino acid metabolism",19,14,"K00013 K00128 K00129 K00603 K00765 K00817 K01590 K01663 K01693 K01745 K01814 K11755 K14085 K18649"]
["ko00640","Propanoate metabolism","Carbohydrate metabolism",19,14,"K00016 K00140 K00249 K00626 K01578 K01895 K01899 K01900 K01961 K01962 K01963 K02160 K05605 K11262"]
["ko04140","Regulation of autophagy ","Transport and catabolism",19,14,"K00914 K07198 K08269 K08331 K08332 K08333 K08334 K08337 K08339 K08341 K08342 K08343 K17888 K17890"]
["ko04623","Cytosolic DNA-sensing pathway","Immune system",17,14,"K03007 K03009 K03013 K03014 K03016 K03018 K03019 K03020 K03021 K03023 K03025 K03026 K03027 K14721"]
["ko00983","Drug metabolism","Xenobiotics biodegradation and metabolism",28,13,"K00088 K00106 K00207 K00699 K00760 K00857 K00876 K01431 K01464 K01489 K01519 K01951 K13421"]
["ko05161","Hepatitis B","Infectious diseases Viral",28,13,"K01110 K02206 K04368 K04371 K04498 K04802 K06620 K06627 K08738 K10140 K10610 K11594 K16197"]
["ko04010","MAPK signalling pathway","Signal transduction",26,13,"K03283 K04368 K04371 K04373 K04392 K04422 K04424 K04426 K04428 K04454 K04459 K04460 K06268"]
["ko00910","Nitrogen metabolism","Energy metabolism",20,13,"K00261 K00262 K00264 K00284 K00366 K01455 K01672 K01673 K01674 K01725 K01915 K02575 K10534"]
["ko05230","Central carbon metabolism in cancer","Cancers Overview",40,12,"K00036 K00161 K00162 K00844 K00850 K00873 K01110 K01834 K04368 K04371 K07203 K11416"]
["ko01040","Biosynthesis of unsaturated fatty acids","Lipid metabolism",32,12,"K00059 K00232 K00507 K01068 K03921 K07513 K10224 K10251 K10255 K10256 K10257 K10703"]
["ko05162","Measles ","Infectious diseases Viral",31,12,"K02206 K03083 K03097 K03115 K03237 K03247 K03283 K04730 K04733 K10144 K14753 K16196"]
["ko05134","Legionellosis ","Infectious diseases Bacterial",30,12,"K03231 K03233 K03283 K03596 K04077 K07874 K07937 K07953 K08517 K08738 K13525 K14416"]
["ko04728","Dopaminergic synapse ","Nervous system",22,12,"K02183 K03083 K03456 K04354 K04382 K04515 K04536 K05858 K06269 K08822 K11583 K11584"]
["ko05202","Transcriptional misregulation in cancer ","Cancers Overview",22,12,"K04454 K04650 K04728 K06067 K11253 K11644 K12823 K13098 K13105 K15188 K15613 K15627"]
["ko04260","Cardiac muscle contraction","Circulatory system",21,12,"K00411 K00412 K00413 K00416 K00417 K00419 K02256 K02261 K02262 K02265 K02266 K02267"]
["ko00670","One carbon pool by folate","Metabolism of cofactors and vitamins",19,12,"K00288 K00297 K00600 K00601 K00602 K00603 K00604 K00605 K01433 K01934 K01938 K13998"]
["ko04150","mTOR signalling pathway","Signal transduction",19,12,"K01110 K02991 K03259 K04371 K04373 K04688 K06276 K07198 K07203 K07204 K08269 K08272"]
["ko00760","Nicotinate and nicotinamide metabolism","Metabolism of cofactors and vitamins",19,12,"K00278 K00763 K00767 K00858 K01081 K01240 K01950 K03426 K03517 K03787 K06210 K18551"]
["ko00790","Folate biosynthesis ","Metabolism of cofactors and vitamins",17,12,"K01113 K01307 K01495 K01633 K01930 K02619 K03635 K03639 K13941 K13950 K13998 K18482"]
["ko04115","p53 signalling pathway","Cell growth and death",32,11,"K01110 K02206 K04506 K04728 K05868 K08738 K10134 K10140 K10143 K10144 K10808"]
["ko00071","Fatty acid degradation","Energy metabolism",29,11,"K00001 K00121 K00128 K00232 K00249 K00626 K01897 K07513 K10527 K13767 K14085"]
["ko04966","Collecting duct acid secretion","Excretory system",24,11,"K02145 K02146 K02147 K02148 K02149 K02150 K02151 K02152 K02153 K02154 K02155"]
["ko00592","alpha-Linolenic acid metabolism","Lipid metabolism",23,11,"K00232 K00454 K01047 K01723 K05894 K07513 K08241 K10525 K10526 K10527 K14674"]
["ko05215","Prostate cancer","Cancers Specific types",22,11,"K01110 K02206 K03083 K04079 K04368 K04371 K04498 K06276 K06620 K07203 K09487"]
["ko04261","Adrenergic signaling in cardiomyocytes","Signal transduction",19,11,"K02183 K03456 K04354 K04371 K04382 K04515 K05850 K05858 K06269 K11583 K11584"]
["ko02020","Two-component system","Signal transduction",16,11,"K00411 K00412 K00413 K00626 K01113 K01915 K02259 K08738 K10255 K11692 K15859"]
["ko00650","Butanoate metabolism","Carbohydrate metabolism",15,11,"K00074 K00139 K00626 K01580 K01640 K01641 K01652 K01653 K16871 K17761 K18121"]
["ko00290","Valine, leucine and isoleucine biosynthesis ","Amino acid metabolism",15,11,"K00052 K00053 K00826 K01649 K01652 K01653 K01687 K01703 K01704 K01754 K14260"]
["ko00380","Tryptophan metabolism","Amino acid metabolism",14,11,"K00128 K00164 K00626 K01426 K03781 K04103 K11816 K11820 K11821 K14085 K16903"]
["ko00450","Selenocompound metabolism","Metabolism of other amino acids",14,11,"K00384 K00549 K00956 K01739 K01760 K01761 K01874 K08247 K11717 K12528 K13811"]
["ko04024","cAMP signalling pathway","Signal transduction",26,10,"K00232 K01115 K02183 K04368 K04371 K04392 K04498 K04515 K05850 K06269"]
["ko04022","cGMP-PKG signalling pathway","Signal transduction",26,10,"K02183 K04368 K04371 K04454 K05850 K05858 K05863 K06268 K06269 K15040"]
["ko04020","Calcium signalling pathway","Signal transduction",25,10,"K01116 K02183 K04515 K04718 K05850 K05857 K05858 K05863 K06268 K15040"]
["ko00310","Lysine  degradation","Amino acid metabolism",21,10,"K00128 K00164 K00626 K00658 K01582 K09188 K11420 K11423 K14085 K14157"]
["ko04014","Ras signalling pathway","Signal transduction",21,10,"K01047 K01115 K01116 K02183 K04368 K04371 K04392 K04536 K10632 K17637"]
["ko05160","Hepatitis C","Infectious diseases Viral",20,10,"K03083 K03237 K03250 K03456 K04354 K04371 K04382 K04706 K06276 K16196"]
["ko05131","Shigellosis ","Infectious diseases Bacterial",19,10,"K04371 K04392 K05754 K05755 K05756 K05757 K05758 K05759 K08339 K12836"]
["ko04530","Tight junction","Cell communication",16,10,"K01110 K03097 K03115 K03456 K04354 K04382 K04424 K06100 K06110 K06111"]
["ko00196","Photosynthesis-antenna proteins","Energy metabolism",13,10,"K08907 K08908 K08909 K08910 K08912 K08914 K08915 K08916 K08917 K14172"]
["ko04612","Antigen processing and presentation","Immune system",26,9,"K01365 K01369 K03283 K04079 K08054 K08057 K08059 K08064 K09489"]
["ko04390","Hippo signalling pathway","Signal transduction",21,9,"K03083 K03456 K04354 K04382 K06269 K06630 K06685 K16175 K16197 "]
["ko04720","Long-term potantiation","Nervous system",21,9,"K02183 K04368 K04371 K04373 K04498 K04515 K05858 K06268 K06269"]
["ko05142","Chagas disease","Infectious diseases Parasitic",19,9,"K01354 K03456 K04354 K04371 K04382 K04730 K04733 K05858 K08057"]
["ko05210","Colorectal cancer","Cancers Specific types",19,9,"K03083 K04368 K04371 K04392 K08734 K08735 K08736 K08737 K08738"]
["ko00565","Ether lipid metabolism","Lipid metabolism",18,9,"K00993 K01047 K01114 K01115 K06123 K13510 K13519 K14674 K16860"]
["ko04350","TGF-beta signalling pathway","Signal transduction",18,9,"K03094 K03347 K03456 K03868 K04371 K04382 K04498 K04681 K04688"]
["ko00460","Cyanoamino acid metabolism","Metabolism of other amino acids",16,9,"K00600 K01188 K01455 K05349 K05350 K08248 K13034 K13035 K18592"]
["ko00300","Lysine biosynthesis ","Amino acid metabolism",15,9,"K00133 K00215 K00928 K01586 K01714 K01778 K10206 K12524 K14085"]
["ko00511","Other glycan degradation","Glycan biosynthesis and metabolism",15,9,"K01190 K01191 K01206 K01227 K01444 K12309 K12373 K15923 K17108"]
["ko00960","Tropane, piperidine and pyridine alkaloid biosynthesis ","Biosynthesis of other secondary metabolites",15,9,"K00276 K00811 K00815 K00817 K01582 K08081 K14454 K14455 K15849"]
["ko05132","Salmonella infection","Infectious diseases Bacterial",14,9,"K04371 K04392 K05754 K05755 K05756 K05757 K05758 K05759 K07897"]
["ko00941","Flavonoid biosynthesis ","Biosynthesis of other secondary metabolites",13,9,"K00475 K00487 K00588 K00660 K05277 K05280 K09754 K13065 K13082"]
["ko00590","Arachidonic acid metabolism","Lipid metabolism",11,9,"K00432 K00461 K01047 K01254 K05309 K07422 K08726 K14674 K18592"]
["ko04122","Sulfur relay system","Folding, sorting and degradation",10,9,"K00566 K01011 K03635 K03639 K04487 K11996 K12161 K14168 K14169"]
["ko05322","Systemic lupus eryrgematous","Immune diseases",45,8,"K11086 K11087 K11088 K11090 K11251 K11252 K11253 K11254"]
["ko05145","Toxoplasmosis ","Infectious diseases Parasitic",32,8,"K00461 K03283 K04371 K04730 K04733 K06276 K08738 K13412"]
["ko03320","PPAR signalling pathway","Endocrine system",26,8,"K00232 K00249 K00507 K00864 K01897 K06276 K07513 K08770"]
["ko04915","Estrogen signaling pathway","Endocrine system",17,8,"K02183 K03283 K04079 K04368 K04371 K05858 K09487 K09571"]
["ko05130","Pathogenic Escherichia coli infection","Infectious diseases Bacterial",17,8,"K05754 K05755 K05756 K05757 K05758 K07374 K07375 K11294"]
["ko04727","GABAergic synapse","Nervous system",16,8,"K01580 K01915 K04536 K06027 K08341 K14207 K15015 K15376"]
["ko04916","Melanogenesis ","Endocrine system",16,8,"K00505 K02183 K03083 K04368 K04371 K04498 K04515 K05858"]
["ko05214","Glioma ","Cancers Specific types",15,8,"K01110 K01116 K02183 K04368 K04371 K04515 K06620 K07203 "]
["ko04391","Hippo signalling pathway","Signal transduction",15,8,"K03456 K04354 K04382 K06630 K06685 K16175 K16197 K16675"]
["ko00950","Isoquinoline alkaloid biosynthesis ","Biosynthesis of other secondary metabolites",13,8,"K00276 K00505 K00811 K00815 K01592 K14454 K14455 K15849"]
["ko04330","Notch signalling pathway","Signal transduction",13,8,"K04498 K04505 K06062 K06063 K06065 K06067 K06170 K06171"]
["ko05100","Bacterial invasion of epithelial cells","Infectious diseases Bacterial",12,8,"K01528 K04392 K04646 K05754 K05755 K05756 K05757 K05758"]
["ko00750","Vitamin B6 metabolism","Metabolism of cofactors and vitamins",11,8,"K00275 K00831 K00868 K01733 K05275 K06215 K08681 K13248"]
["ko00730","Thiamine metabolism","Metabolism of cofactors and vitamins",10,8,"K00878 K00949 K01662 K03146 K03147 K04487 K06928 K14153"]
["ko00904","Diterpenoid biosynthesis ","Metabolism",9,8,"K04120 K04121 K04122 K04123 K04124 K04125 K05282 K17982"]
["ko03450","Non-homologous end-joining","Replication and repair",8,8,"K03512 K04799 K10777 K10865 K10866 K10884 K10885 K10886"]
["ko04920","Adipocytokine signalling pathway","Endocrine system",21,7,"K01897 K07198 K07199 K07200 K07203 K07297 K07359"]
["ko05014","Amyotrophic lateral sclerosis (ALS)","Neurodegenerative diseases",21,7,"K03781 K04392 K04426 K04565 K06268 K08738 K11518"]
["ko04510","Focal adhesion","Cell communication",19,7,"K01110 K03083 K04368 K04371 K04392 K06269 K06276"]
["ko04724","Glutamatergic synapse","Nervous system",19,7,"K01115 K01915 K04371 K04536 K05858 K06268 K14207"]
["ko00780","Biotin metabolism","Metabolism of cofactors and vitamins",16,7,"K00059 K00208 K00652 K00833 K01012 K02372 K09458"]
["ko04062","Chemokine signalling pathway","Immune system",16,7,"K03083 K04368 K04371 K04392 K04536 K05858 K08822"]
["ko04064","NF-kappa B signalling pathway","Signal transduction",15,7,"K01116 K03097 K03115 K04728 K04730 K04733 K10577"]
["ko04015","Rap1 signalling pathway","Signal transduction",15,7,"K01116 K02183 K04368 K04371 K04392 K05759 K05858"]
["ko05211","Renal cell carcinoma","Cancers Specific types",15,7,"K01679 K03868 K03872 K04368 K04371 K04392 K04498"]
["ko05222","Small cell lung cancer ","Cancers Specific types",15,7,"K01110 K01522 K02206 K02219 K03875 K06620 K08738"]
["ko04912","GnRH signalling pathway","Endocrine system",14,7,"K01115 K02183 K04368 K04371 K04428 K04515 K05858"]
["ko04012","ErbB signalling pathway","Signal transduction",13,7,"K01116 K03083 K04368 K04371 K04515 K04688 K07203"]
["ko04710","Circadian rhythm","Environmental adaptation",12,7,"K02295 K03094 K03347 K03868 K07198 K07199 K07200"]
["ko04270","Vascular smooth muscle contraction","Circulatory system",12,7,"K01047 K02183 K04368 K04371 K05858 K06269 K12315"]
["ko00073","Cutin, suberine and wax biosynthesis ","Lipid metabolism",11,7,"K13356 K15398 K15400 K15402 K15403 K15404 K17991"]
["ko00982","Drug metabolism-cytochorem P450","Xenobiotics biodegradation and metabolism",34,6,"K00001 K00121 K00129 K00485 K00699 K00799"]
["ko00830","Retinol metabolism","Metabolism of cofactors and vitamins",23,6,"K00001 K00121 K00699 K11147 K11153 K11155"]
["ko04660","T cell receptor signalling pathway","Immune system",17,6,"K01116 K03083 K04368 K04371 K06268 K06276"]
["ko04370","VEGF signalling pathway","Signal transduction",17,6,"K01116 K04368 K04371 K04392 K04718 K06268"]
["ko05213","Endometrial cancer","Cancers Specific types",14,6,"K01110 K03083 K04368 K04371 K06276 K08734"]
["ko05212","Pancreatic cancer","Cancers Specific types",14,6,"K04368 K04371 K04392 K04482 K06620 K08775"]
["ko04918","Thyroid hormone synthesis","Endocrine system",14,6,"K00383 K00432 K05858 K08054 K09487 K09490"]
["ko02010","ABC transporters","Membrane transport",13,6,"K05657 K05658 K05663 K06148 K11710 K15497"]
["ko04961","Endocrine and other factor-regulated calcium reabsorption","Excretory system",13,6,"K01528 K04646 K05858 K07904 K11824 K11826"]
["ko00062","Fatty acid elongation","Lipid metabolism",13,6,"K01068 K01074 K07512 K10251 K10703 K15397"]
["ko05223","Non-small cell lung cancer","Cancers Specific types",12,6,"K01116 K01522 K04368 K04371 K06276 K06620"]
["ko04550","Signaling pathways regulating pluripotency of stem cells","Signal transduction",12,6,"K03083 K04368 K04371 K11138 K14439 K15613"]
["ko04360","Axon guidance","Development",26,5,"K03083 K04371 K04392 K05765 K06268   "]
["ko05133","Pertussis ","Infectious diseases Bacterial",25,5,"K02183 K04371 K04730 K04733 K05765"]
["ko00945","Stilbenoid, diarylheptanoid and gingerol biosynthesis ","Biosynthesis of other secondary metabolites",20,5,"K00487 K00517 K00588 K09754 K13065"]
["ko04210","Apoptosis ","Cell growth and death",17,5,"K04728 K04730 K04733 K06268 K08738"]
["ko04662","B cell receptor signalling pathway","Immune system",17,5,"K03083 K04368 K04371 K04392 K06268  "]
["ko04620","Toll-like receptor signalling pathway","Immune system",16,5,"K04368 K04371 K04392 K04730 K04733"]
["ko04962","Vasopressin-regulated water reabsorption","Excretory system",15,5,"K06027 K07904 K09866 K10418 K12462"]
["ko04725","Cholinergic synapse","Nervous system",14,5,"K04368 K04371 K04515 K04536 K05858"]
["ko04540","Gap junction","Cell communication",14,5,"K04368 K04371 K05858 K07374 K07375"]
["ko04380","Osteoclast differentiation","Development",14,5,"K04368 K04371 K04392 K06268 K08008"]
["ko00740","Riboflavin metabolism","Metabolism of cofactors and vitamins",14,5,"K00505 K00793 K00794 K00861 K14652"]
["ko04726","Serotonergic synapse","Nervous system",14,5,"K00461 K04368 K04371 K04536 K05858"]
["ko04520","Adherens junction","Cell communication",13,5,"K03097 K03115 K04371 K04392 K04498"]
["ko04713","Circadian entrainment","Environmental adaptation",13,5,"K02183 K04371 K04515 K04536 K05858"]
["ko04650","Natural killer cell mediated cytotoxicity ","Immune system",12,5,"K01116 K04368 K04371 K04392 K06268  "]
["ko05020","Prion diseases","Neurodegenerative diseases",12,5,"K04368 K04371 K04565 K09490 K09553"]
["ko00521","Streptomycin biosynthesis","Biosynthesis of other secondary metabolites",12,5,"K00844 K00973 K01092 K01835 K01858"]
["ko00980","Metabolism of xenobiotics by cytochrome P450","Xenobiotics biodegradation and metabolism",11,5,"K00001 K00121 K00129 K00699 K00799"]
["ko03070","Bacterial secretion system","Membrane transport",10,5,"K03070 K03106 K03116 K03118 K03217"]
["ko04664","Fc epsilon RI signaling pathway","Immune system",10,5,"K01116 K04368 K04371 K04392 K06276"]
["ko00531","Glycosaminoglycan  degradation","Glycan biosynthesis and metabolism",9,5,"K01205 K07964 K10532 K12309 K12373  "]
["ko00540","Lipopolysaccharide biosynthesis ","Glycan biosynthesis and metabolism",9,5,"K00677 K00748 K00979 K01627 K02527  "]
["ko04730","Long-term depression","Nervous system",9,5,"K03456 K04368 K04371 K04382 K05858  "]
["ko04750","Inflammatory mediator regulation of TRP channels","Immune system",8,5,"K01116 K02183 K04515 K05858 K06269  "]
["ko04978","Mineral absorption","Digestive system",8,5,"K00510 K00522 K07213 K14685 K14686"]
["ko04972","Pancreatic secretion","Digestive system",8,5,"K01047 K04392 K05850 K05858 K07904"]
["ko00905","Brassinosteroid biosynthesis ","Biosynthesis of other secondary metabolites",6,5,"K09587 K09588 K09591 K12640 K15639  "]
["ko00660","C5-Branched dibasic acid metabolism","Carbohydrate metabolism",6,5,"K00052 K01652 K01653 K01703 K01704  "]
["ko00909","Sesquiterpenoid and triterpene biosynthesis ","Metabolism of terpenoids and polyketides",5,5,"K00511 K00801 K14184 K15813 K15891"]
["ko04975","Fat digestion and absorption","Digestive system",18,4,"K01047 K11155 K14455 K14457"]
["ko01220","Degradation of aromatic compounds","Metabolism",13,4,"K00001 K00002 K00121 K00487"]
["ko05218","Melanoma ","Cancers Specific types",12,4,"K01110 K04368 K04371 K06620"]
["ko04917","Prolactin signalling pathway","Endocrine system",12,4,"K00512 K03083 K04368 K04371"]
["ko04930","Type II diabetes mellitus","Endocrine and metabolic diseases",11,4,"K00844 K00873 K04371 K07203  "]
["ko05031","Amphetamine addiction","Substance dependence",10,4,"K02183 K04515 K06268 K06269"]
["ko04112","Cell cycle-Caulobacter","Cell growth and death",10,4,"K01338 K01358 K03531 K03544"]
["ko05204","Chemical carcinogenesis","Cancers Overview",10,4,"K00121 K00129 K00699 K00799"]
["ko00625","Chloroalkane and chloroalkene degradation","Xenobiotics biodegradation and metabolism",10,4,"K00001 K00121 K00128 K08726"]
["ko04621","NOD-like receptor signalling pathway","Immune system",10,4,"K04079 K04371 K09487 K12795"]
["ko04723","Retrograde endocannabinoid signaling","Nervous system",10,4,"K04371 K04536 K05858 K15015  "]
["ko04973","Carbohydrate digestion and absorption","Digestive system",9,4,"K00844 K01176 K01229 K04626  "]
["ko00603","Glycosphingolipid biosynthesis -globo series","Glycan biosynthesis and metabolism",9,4,"K00780 K01988 K07407 K12373"]
["ko05140","Leishmaniasis ","Infectious diseases Parasitic",9,4,"K01404 K04371 K04730 K04733  "]
["ko04668","TNF signalling pathway","Signal transduction",9,4,"K04368 K04371 K04426 K17065  "]
["ko05221","Acute myeloid leukemia","Cancers Specific types",8,4,"K04368 K04371 K04688 K07203  "]
["ko05146","Amoebiasis","Infectious diseases Parasitic",7,4,"K01476 K05858 K07897 K13963  "]
["ko05220","Chronic myeloid leukemia","Cancers Specific types",7,4,"K04368 K04371 K06067 K06620  "]
["ko04622","RIG-I-like receptor signalling pathway","Immune system",7,4,"K00863 K08339 K11594 K12655  "]
["ko00627","Aminobenzoate  degradation","Xenobiotics biodegradation and metabolism",6,4,"K00517 K01113 K01426 K01512  "]
["ko00643","Styrene  degradation","Xenobiotics biodegradation and metabolism",6,4,"K00451 K01426 K01555 K01800"]
["ko00591","Linoleic acid metabolism","Lipid metabolism",5,4,"K00454 K01047 K14674 K15718  "]
["ko00253","Tetracycline biosynthesis ","Metabolism of terpenoids and polyketides",4,4,"K01961 K01962 K01963 K02160"]
["ko00908","Zeatin biosynthesis ","Metabolism of terpenoids and polyketides",4,4,"K00279 K00791 K10717 K10760  "]
["ko00362","Benzoate degradation","Xenobiotics biodegradation and metabolism",10,3,"K00074 K00626 K07513  "]
["ko04976","Bile secretion","Digestive system",9,3,"K00021 K05658 K09866"]
["ko04340","Hedgehog signalling pathway","Signal transduction",9,3,"K02218 K03083 K06228"]
["ko00072","Synthesis and degradation of ketone bodies","Lipid metabolism",8,3,"K00626 K01640 K01641"]
["ko00440","Phosphonate and phosphinate metabolism","Metabolism of other amino acids",7,3,"K00967 K00968 K00993"]
["ko05416","Viral myocarditis","Cardiovascular diseases",7,3,"K03260 K04392 K08738"]
["ko05219","Bladder cancer","Cancers Specific types",6,3,"K04368 K04371 K06620  "]
["ko04971","Gastric acid secretion","Digestive system",6,3,"K02183 K04515 K05858  "]
["ko04670","Leukocyte transendothelial migration","Immune system",6,3,"K01116 K04392 K08008"]
["ko04745","Phototransduction-fly","Sensory system",6,3,"K02183 K04515 K05858"]
["ko05216","Thyroid cancer","Cancers Specific types",6,3,"K04368 K04371 K09291  "]
["ko05143","African trypanosomiasis","Infectious diseases Parasitic",5,3,"K01354 K01404 K05858  "]
["ko00604","Glycosphingolipid biosynthesis -ganglio series","Glycan biosynthesis and metabolism",5,3,"K00780 K12309 K12373  "]
["ko00430","Taurine and hypotaurine metabolism","Metabolism of other amino acids",5,3,"K01580 K10712 K18592"]
["ko05410","Hypertrophic cardiomyopathy","Cardiovascular diseases",4,3,"K07198 K07199 K07200"]
["ko00902","Monoterpenoid biosynthesis ","Metabolism",4,3,"K07385 K15086 K15095"]
["ko04611","Platelet activation","Immune system",4,3,"K04371 K05858 K06269  "]
["ko04974","Protein degradation and absorption","Digestive system",4,3,"K01278 K01285 K14207  "]
["ko04970","Salivary secretion ","Digestive system",4,3,"K02183 K05850 K05858"]
["ko00140","Steroid hormone biosynthesis ","Lipid metabolism",4,3,"K00512 K00699 K10251"]
["ko05217","Basal cell carcinoma","Cancers Specific types",8,2,"K03083 K06228"]
["ko05032","Morphine addiction","Substance dependence",7,2,"K04536 K15015"]
["ko04744","Phototransduction ","Sensory system",7,2,"K02183 K04536"]
["ko00626","Naphthalene degradation","Xenobiotics biodegradation and metabolism",6,2,"K00001 K00121  "]
["ko04742","Taste transduction","Sensory system",6,2,"K04536 K04626"]
["ko04940","Type I diabetes mellitus","Endocrine and metabolic diseases",6,2,"K01580 K04077"]
["ko04960","Aldosterone-regulated sodium absorption","Digestive system",5,2,"K04371 K06276"]
["ko00361","Chlorocyclohexane and chlorobengene degradation","Xenobiotics biodegradation and metabolism",5,2,"K00224 K01061"]
["ko04320","Dorso-ventral axis formation","Development",5,2,"K04368 K04371"]
["ko04013","MAPK signalling pathway-fly","Signal transduction",5,2,"K04368 K04371  "]
["ko00401","Novobiocin biosynthesis ","Biosynthesis of other secondary metabolites",5,2,"K00815 K00817"]
["ko04740","Olfactory transduction","Sensory system",5,2,"K02183 K04515 "]
["ko00514","Other type of O-glycan biosynthesis ","Glycan biosynthesis and metabolism",5,2,"K03691 K09667"]
["ko00965","Betalain biosynthesis ","Biosynthesis of other secondary metabolites",4,2,"K00505 K15777"]
["ko05340","Primary immunodeficiency ","Immune diseases",4,2,"K01488 K03648"]
["ko04911","Insulin secretion","Endocrine system",4,2,"K04515 K05858"]
["ko00785","Lipoic acid metabolism","Metabolism of cofactors and vitamins",4,2,"K03644 K03801"]
["ko04011","MAPK signalling pathway-yeast","Signal transduction",4,2,"K01759 K09291"]
["ko04913","Ovarian steriodogenesis","Endocrine system",4,2,"K00461 K00512"]
["ko00232","Caffeine metabolism","Biosynthesis of other secondary metabolites",3,2,"K00106 K00365"]
["ko00966","Glucosinolate biosynthesis ","Biosynthesis of other secondary metabolites",3,2,"K11820 K11821"]
["ko04630","Jak-STAT signalling pathway","Signal transduction",3,2,"K04498 K04706  "]
["ko00903","Limonene and pinene degradation","Metabolism of terpenoids and polyketides",3,2,"K00128 K00517"]
["ko00624","Polycyclic aromatic hydrocarbon degradation","Xenobiotics biodegradation and metabolism",3,2,"K00224 K00517"]
["ko00332","Carbapenem biosynthesis ","Biosynthesis of other secondary metabolites",2,2,"K00147 K00931"]
["ko00944","Flavone and flavonol biosynthesis ","Biosynthesis of other secondary metabolites",2,2,"K05280 K10757  "]
["ko00534","Glycosaminoglycan biosynthesis ","Glycan biosynthesis and metabolism",2,2,"K00771 K02367  "]
["ko00523","Polyketide sugar unit biosynthesis ","Metabolism of terpenoids and polyketides",2,2,"K00973 K12451"]
["ko04964","Proximal tubule bicarbonate reclamation","Excretory system",2,2,"K00025 K00261"]
["ko00363","Bisphenol degradation","Xenobiotics biodegradation and metabolism",12,1,"K00517"]
["ko05033","Nicotine addiction","Substance dependence",7,1,"K15015"]
["ko00524","Butirosin and neomycin biosynthesis ","Biosynthesis of other secondary metabolites",4,1,"K00844"]
["ko04711","Circadian rhythm-fly","Environmental adaptation",4,1,"K03083"]
["ko00471","D-Glutamine and D-glutamate metabolism","Metabolism of other amino acids",2,1,"K00261"]
["ko00364","Fluorobenzoate degradation","Xenobiotics biodegradation and metabolism",2,1,"K01061"]
["ko00281","Geraniol degradation","Metabolism of terpenoids and polyketides",2,1,"K01640"]
["ko00981","Insect hormone biosynthesis ","Metabolism of terpenoids and polyketides",2,1,"K14985"]
["ko00623","Toluene degradation","Xenobiotics biodegradation and metabolism",2,1,"K01061"]
["ko00254","Aflatoxin biosynthesis ","Biosynthesis of other secondary metabolites",1,1,"K11262"]
["ko00942","Anthocyanin biosynthesis ","Biosynthesis of other secondary metabolites",1,1,"K17193"]
["ko01051","Biosynthesis of ansamycins","Metabolism of terpenoids and polyketides",1,1,"K00615"]
["ko01053","Biosynthesis of siderophore group nonribosomal peptides","Biosynthesis of other secondary metabolites",1,1,"K02552"]
["ko00930","Caprolactam degradation","Xenobiotics biodegradation and metabolism",1,1,"K00002"]
["ko00351","DDT degradation","Xenobiotics biodegradation and metabolism",1,1,"K00224"]
["ko00532","Glycosaminoglycan biosynthesis ","Glycan biosynthesis and metabolism",1,1,"K00771"]
["ko00533","Glycosaminoglycan biosynthesis - keratan sulfate ","Glycan biosynthesis and metabolism",1,1,"K00780"]
["ko00512","Mucin type O-glycan biosynthesis ","Glycan biosynthesis and metabolism",1,1,"K00780"]
["ko00550","Peptidoglycan biosynthesis ","Carbohydrate metabolism",1,1,"K01000"]
["ko04977","Vitamin degradation and absorption","Digestive system",1,1,"K14617"]
[{"$nulls":3},11582]