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{"sheet":"F_Up_By_2Plus_GOTERM_MF_DIRECT","index":0,"n_rows":55,"n_cols":8,"rows_kept":55,"flags":["formulas_cached_only"]}
["Category","Term","Count","PValue","Fold_Enrichment","Bonferroni","Benjamini","FDR"]
["GOTERM_MF_DIRECT","GO:0005515~protein binding",1478,1.5944980750682598e-22,1.1731027386294792,2.6054098546615364e-19,2.6054098546615364e-19,2.676731563201859e-19]
["GOTERM_MF_DIRECT","GO:0003700~transcription factor activity",207,5.488287762099248e-10,1.5019322344676589,8.967857922925759e-07,4.48392996732494e-07,9.213352303305555e-07]
["GOTERM_MF_DIRECT","GO:0003677~DNA binding",324,2.5302238250841796e-09,1.3495622976376063,4.134377161402192e-06,1.378127619688918e-06,4.247562224168888e-06]
["GOTERM_MF_DIRECT","GO:0008134~transcription factor binding",78,1.112867039093989e-08,1.9150479082674483,1.818408225073842e-05,4.546051562526188e-06,1.868202994526058e-05]
["GOTERM_MF_DIRECT","GO:0001077~transcriptional activator activity",67,3.3740501642972335e-08,1.97954865267889,5.5130460829055934e-05,1.1026335323238713e-05,5.664117316284135e-05]
["GOTERM_MF_DIRECT","GO:0004674~protein serine/threonine kinase activity",94,4.7738194765189086e-08,1.7431846344485749,7.800116980216654e-05,1.3000617499869806e-05,8.01395037441921e-05]
["GOTERM_MF_DIRECT","GO:0046332~SMAD binding",21,4.2878488749897996e-07,3.4052909138065193,0.0007003892692128977,0.00010008565629093802,0.0007198115666406935]
["GOTERM_MF_DIRECT","GO:0046872~metal ion binding",373,5.359191198230594e-07,1.2570475952620948,0.0008753087700883455,0.00010945551887009408,0.0008996596342125684]
["GOTERM_MF_DIRECT","GO:0008270~zinc ion binding",226,1.047968645057411e-06,1.3480230192827303,0.001710916374346838,0.0001902465300922529,0.0017592417254408412]
["GOTERM_MF_DIRECT","GO:0043565~sequence-specific DNA binding",115,1.169442971751903e-06,1.5480017989311672,0.001909046381722068,0.00019106883734798521,0.001963160738083225]
["GOTERM_MF_DIRECT","GO:0003730~mRNA 3'-UTR binding",22,1.1935968365348037e-06,3.1306173026831554,0.0019484377206929748,0.00017728777309844457,0.0020037077961387872]
["GOTERM_MF_DIRECT","GO:0000978~RNA polymerase II core promoter proximal region sequence-specific DNA binding",84,2.9309816270750585e-06,1.6498874286611864,0.004777780916756291,0.00039902295225879847,0.004920212601178253]
["GOTERM_MF_DIRECT","GO:0004702~receptor signaling protein serine/threonine kinase activity",22,5.454874910651063e-06,2.8943442987070678,0.008873684305375051,0.000685402689921677,0.00915686721681963]
["GOTERM_MF_DIRECT","GO:0003682~chromatin binding",89,7.63544128186653e-06,1.5871450891654544,0.012398851593198425,0.0008907715048718234,0.012817070910098318]
["GOTERM_MF_DIRECT","GO:0004842~ubiquitin-protein transferase activity",77,1.1925421179992648e-05,1.6319175301220699,0.01929762456067585,0.0012982401827565935,0.020017676441330682]
["GOTERM_MF_DIRECT","GO:0044325~ion channel binding",35,1.2690634563799753e-05,2.1596977771929247,0.02052310305732341,0.0012951997824297568,0.021302013427759725]
["GOTERM_MF_DIRECT","GO:0003714~transcription corepressor activity",53,1.4947553656202784e-05,1.8204686822812706,0.0241286211493168,0.0014357028157802043,0.025089944452216798]
["GOTERM_MF_DIRECT","GO:0005524~ATP binding",270,2.3166355551748493e-05,1.2592905720431178,0.03714674641816396,0.0021008048499491228,0.0388829423909276]
["GOTERM_MF_DIRECT","GO:0044212~transcription regulatory region DNA binding",53,6.0308855738517705e-05,1.7350006690286286,0.0938474792911187,0.005173290201231141,0.10119409542695969]
["GOTERM_MF_DIRECT","GO:0004843~thiol-dependent ubiquitin-specific protease activity",26,8.700427953450609e-05,2.2661400247831476,0.13252724812728434,0.007083352836873781,0.1459564178047157]
["GOTERM_MF_DIRECT","GO:0019003~GDP binding",20,0.00010391834842799391,2.5824957547386296,0.15617605721731842,0.008053651535251838,0.17430780877337737]
["GOTERM_MF_DIRECT","GO:0061630~ubiquitin protein ligase activity",47,0.00012901616288063771,1.7525064774135404,0.19008502861202858,0.009537229847962571,0.2163628576855814]
["GOTERM_MF_DIRECT","GO:0019838~growth factor binding",13,0.00015593614256733936,3.357244481160219,0.22494363656346217,0.011017962484517474,0.2614526897261049]
["GOTERM_MF_DIRECT","GO:0008022~protein C-terminus binding",45,0.00027009522533704257,1.7240287593447448,0.3568615185824384,0.018223376120245053,0.45245150951521707]
["GOTERM_MF_DIRECT","GO:0016874~ligase activity",60,0.0005097391116796021,1.5494974528431777,0.5653117037101942,0.03277588055394054,0.85227977488046]
["GOTERM_MF_DIRECT","GO:0035198~miRNA binding",9,0.0007722043425180184,3.9221654275092934,0.7169889463730899,0.0473891684129264,1.2884507527970879]
["GOTERM_MF_DIRECT","GO:0031625~ubiquitin protein ligase binding",62,0.0008715595514096486,1.5063058862134027,0.7594312275426274,0.05140040419509163,1.4530902711573312]
["GOTERM_MF_DIRECT","GO:0005251~delayed rectifier potassium channel activity",14,0.0009535960358654104,2.7116205424755613,0.7896367183961315,0.05415416693527064,1.5888365998997345]
["GOTERM_MF_DIRECT","GO:0000900~translation repressor activity",7,0.0010770426011172483,4.88091697645601,0.8280989104340533,0.05891186589287178,1.7927731124994573]
["GOTERM_MF_DIRECT","GO:0000980~RNA polymerase II distal enhancer sequence-specific DNA binding",20,0.0014558266950534771,2.145458011629015,0.9075006884841254,0.07628509801415617,2.4160550719468876]
["GOTERM_MF_DIRECT","GO:0003707~steroid hormone receptor activity",18,0.0016137383668376924,2.2412373871481677,0.9285657887257892,0.08160558500957793,2.6747953785051792]
["GOTERM_MF_DIRECT","GO:0048407~platelet-derived growth factor binding",7,0.0020824115444291152,4.437197251323646,0.966833278143848,0.10097461511649465,3.4389286400010044]
["GOTERM_MF_DIRECT","GO:0035197~siRNA binding",6,0.0023119035176280504,5.229553903345725,0.9772234520583816,0.1082832877284936,3.8110353646478523]
["GOTERM_MF_DIRECT","GO:0005249~voltage-gated potassium channel activity",18,0.002454505289372338,2.1639533393154724,0.9819677202371088,0.11139782550618482,4.0415753571400925]
["GOTERM_MF_DIRECT","GO:0004672~protein kinase activity",72,0.0026482165874886845,1.3984322415632022,0.9868709205351242,0.11644158987525889,4.3539103101277075]
["GOTERM_MF_DIRECT","GO:0001103~RNA polymerase II repressing transcription factor binding",11,0.002938306805851486,2.8407453302124925,0.9918379576885612,0.12502748243305498,4.819856669526191]
["GOTERM_MF_DIRECT","GO:0001078~transcriptional repressor activity",28,0.00347377596068052,1.7588890005246882,0.996606968968786,0.14245063322430818,5.6743319170917905]
["GOTERM_MF_DIRECT","GO:0004386~helicase activity",23,0.0035588053085049824,1.8867410161090457,0.9970485534478488,0.14212903014116762,5.809351990663069]
["GOTERM_MF_DIRECT","GO:0005516~calmodulin binding",42,0.0038659190597035513,1.5494974528431782,0.9982164573490762,0.1498019790025661,6.29551276662772]
["GOTERM_MF_DIRECT","GO:0030165~PDZ domain binding",23,0.004148203538342703,1.864802167084522,0.9988775732367468,0.15617196455599713,6.74028657581589]
["GOTERM_MF_DIRECT","GO:0048027~mRNA 5'-UTR binding",6,0.0045887567714275835,4.648492358529533,0.9994553050740128,0.16748132634108184,7.430467030901666]
["GOTERM_MF_DIRECT","GO:0004675~transmembrane receptor protein serine/threonine kinase activity",6,0.0045887567714275835,4.648492358529533,0.9994553050740128,0.16748132634108184,7.430467030901666]
["GOTERM_MF_DIRECT","GO:0005201~extracellular matrix structural constituent",19,0.0052275033858174185,1.9773437644491296,0.9998091732545872,0.1844627704678703,8.42261517650732]
["GOTERM_MF_DIRECT","GO:0003723~RNA binding",101,0.005467596610579209,1.2874709183130244,0.9998713694419691,0.1880680500060976,8.792952927014719]
["GOTERM_MF_DIRECT","GO:0004535~poly(A)-specific ribonuclease activity",7,0.005981967866045593,3.754551520350777,0.9999447635826599,0.1997376266202514,9.581622026020419]
["GOTERM_MF_DIRECT","GO:0035064~methylated histone binding",16,0.0061696320229880745,2.1049776717869584,0.9999594269219336,0.20126026857622736,9.867761323155499]
["GOTERM_MF_DIRECT","GO:0031490~chromatin DNA binding",17,0.006241253834516005,2.0437337093535013,0.9999639342397098,0.1994008757799183,9.976741367104303]
["GOTERM_MF_DIRECT","GO:0016301~kinase activity",50,0.0065479860537499416,1.446626252654419,0.9999782216167528,0.20419061573217126,10.442066135725048]
["GOTERM_MF_DIRECT","GO:0018024~histone-lysine N-methyltransferase activity",13,0.0066931150534804635,2.3242461792647666,0.9999828465961084,0.20436179023141576,10.661443320951625]
["GOTERM_MF_DIRECT","GO:0008536~Ran GTPase binding",11,0.0069744169572450035,2.5566707971912432,0.9999892017230235,0.20815553198414738,11.0852213142289]
["GOTERM_MF_DIRECT","GO:0005154~epidermal growth factor receptor binding",11,0.008997913733028573,2.4741975456689453,0.9999996146588711,0.2557533177312885,14.07834910529595]
["GOTERM_MF_DIRECT","GO:0042800~histone methyltransferase activity (H3-K4 specific)",8,0.009204567156532216,3.0989949056863555,0.9999997259375946,0.2564154086828875,14.378636250138443]
["GOTERM_MF_DIRECT","GO:0001104~RNA polymerase II transcription cofactor activity",12,0.009788823678994498,2.3242461792647666,0.9999998954644226,0.26590024474055457,15.22228597585763]
["GOTERM_MF_DIRECT","GO:0046982~protein heterodimerization activity",86,0.009831574250495542,1.2895817510759349,0.9999999025849263,0.2625884636303226,15.283708636529102]