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{"sheet":"Sheet1","index":0,"n_rows":372,"n_cols":13,"rows_kept":372,"merged":[[1,0,1,2],[331,0,331,2],[347,0,347,2]],"flags":["formulas_cached_only"]}
[]
["supplementary material 1"]
["Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["GO:0022403~cell cycle phase",49,10.2941176470588,{"v":1.80148971262769e-16,"d":"1.80E-16"},"PRC1, NEK2, DBF4, TTK, AURKA, CEP55, AURKB, CCNG2, RPA1, KIF2C, CDCA8, SAC3D1, OIP5, NCAPG, DNAJC2, HELLS, ASPM, CDCA3, TRIP13, CDC7, CDK1, CDC6, KIF11, DLGAP5, TPX2, NUSAP1, CDC20, BIRC5, NDC80, PBK, HMGA2, CDKN3, UBE2C, CDK4, RAD54L, NCAPD2, CDC25B, CCNB1, MAD2L1, CCNB2, EREG, ZWINT, CKS2, BUB1B, RRS1, RAD54B, ID4, RUVBL1, ACVR1",398,414,13528,4.02296506688029,{"v":5.44897460486026e-13,"d":"5.45E-13"},{"v":5.44897460486026e-13,"d":"5.45E-13"},{"v":3.88578058618804e-13,"d":"3.89E-13"}]
["GO:0007049~cell cycle",68,14.2857142857142,{"v":7.99858315769822e-16,"d":"8.00E-16"},"E2F3, PRC1, DBF4, JAG2, TTK, AURKA, AURKB, CCNE2, KIF2C, CDCA8, CDC45, MCM7, OIP5, FANCI, DNAJC2, ASPM, CDCA3, CDC7, CDK1, CDC6, KIF11, PDPN, TPX2, NUSAP1, MCM2, PBK, HMGA2, CDK4, UBE2C, AHR, NCAPD2, MCM6, MAD2L1, EREG, ZWINT, BUB1B, RUVBL1, ACVR1, CKS1B, NEK2, FOXM1, CEP55, CCNG2, MLF1, RPA1, SAC3D1, HJURP, NCAPG, HELLS, TRIP13, KAT2B, DLGAP5, GMNN, CDC20, BIRC5, NDC80, RACGAP1, CDKN3, RAD54L, PSMB9, CDC25B, CCNB1, SH3BP4, CCNB2, CKS2, RRS1, RAD54B, ID4",398,776,13528,2.97850075117857,{"v":1.90714111170109e-12,"d":"1.91E-12"},{"v":9.53570555850547e-13,"d":"9.54E-13"},{"v":1.36557432028894e-12,"d":"1.37E-12"}]
["GO:0000279~M phase",42,8.8235294117647,{"v":3.39087064498516e-15,"d":"3.39E-15"},"PRC1, NEK2, TTK, AURKA, CEP55, AURKB, CCNG2, RPA1, KIF2C, CDCA8, SAC3D1, OIP5, NCAPG, HELLS, ASPM, CDCA3, TRIP13, CDK1, CDC6, KIF11, DLGAP5, TPX2, NUSAP1, CDC20, BIRC5, NDC80, PBK, HMGA2, UBE2C, RAD54L, NCAPD2, CDC25B, CCNB1, MAD2L1, CCNB2, EREG, ZWINT, CKS2, BUB1B, RRS1, RAD54B, RUVBL1",398,329,13528,4.33914252111621,{"v":8.44591063753341e-12,"d":"8.45E-12"},{"v":2.81530354584447e-12,"d":"2.82E-12"},{"v":6.06181771445335e-12,"d":"6.06E-12"}]
["GO:0000278~mitotic cell cycle",44,9.24369747899159,{"v":8.57574534031353e-15,"d":"8.58E-15"},"PRC1, NEK2, DBF4, TTK, AURKA, CEP55, AURKB, CCNG2, KIF2C, CDCA8, SAC3D1, NCAPG, OIP5, DNAJC2, HELLS, ASPM, CDCA3, CDC7, CDK1, CDC6, KIF11, DLGAP5, TPX2, NUSAP1, CDC20, BIRC5, NDC80, PBK, HMGA2, CDKN3, UBE2C, CDK4, NCAPD2, PSMB9, CDC25B, CCNB1, MAD2L1, CCNB2, ZWINT, BUB1B, RRS1, ID4, RUVBL1, ACVR1",398,370,13528,4.04204807822898,{"v":2.0978552228712e-11,"d":"2.10E-11"},{"v":5.24469356832923e-12,"d":"5.24E-12"},{"v":1.50435219836708e-11,"d":"1.50E-11"}]
["GO:0007067~mitosis",34,7.14285714285714,{"v":9.01975036733882e-15,"d":"9.02E-15"},"NEK2, AURKA, CEP55, AURKB, CCNG2, KIF2C, CDCA8, SAC3D1, NCAPG, OIP5, HELLS, ASPM, CDCA3, CDK1, CDC6, KIF11, DLGAP5, TPX2, NUSAP1, BIRC5, NDC80, CDC20, PBK, HMGA2, UBE2C, NCAPD2, CDC25B, CCNB1, MAD2L1, CCNB2, ZWINT, BUB1B, RRS1, RUVBL1",398,220,13528,5.25299223389675,{"v":2.2068347149684e-11,"d":"2.21E-11"},{"v":4.41369163439731e-12,"d":"4.41E-12"},{"v":1.58317803311547e-11,"d":"1.58E-11"}]
["GO:0000280~nuclear division",34,7.14285714285714,{"v":9.01975036733882e-15,"d":"9.02E-15"},"NEK2, AURKA, CEP55, AURKB, CCNG2, KIF2C, CDCA8, SAC3D1, NCAPG, OIP5, HELLS, ASPM, CDCA3, CDK1, CDC6, KIF11, DLGAP5, TPX2, NUSAP1, BIRC5, NDC80, CDC20, PBK, HMGA2, UBE2C, NCAPD2, CDC25B, CCNB1, MAD2L1, CCNB2, ZWINT, BUB1B, RRS1, RUVBL1",398,220,13528,5.25299223389675,{"v":2.2068347149684e-11,"d":"2.21E-11"},{"v":4.41369163439731e-12,"d":"4.41E-12"},{"v":1.58317803311547e-11,"d":"1.58E-11"}]
["GO:0000087~M phase of mitotic cell cycle",34,7.14285714285714,{"v":1.53301844399361e-14,"d":"1.53E-14"},"NEK2, AURKA, CEP55, AURKB, CCNG2, KIF2C, CDCA8, SAC3D1, NCAPG, OIP5, HELLS, ASPM, CDCA3, CDK1, CDC6, KIF11, DLGAP5, TPX2, NUSAP1, BIRC5, NDC80, CDC20, PBK, HMGA2, UBE2C, NCAPD2, CDC25B, CCNB1, MAD2L1, CCNB2, ZWINT, BUB1B, RRS1, RUVBL1",398,224,13528,5.15918880114859,{"v":3.75979247735358e-11,"d":"3.76E-11"},{"v":6.2663207955893e-12,"d":"6.27E-12"},{"v":2.6967317268145e-11,"d":"2.70E-11"}]
["GO:0005578~proteinaceous extracellular matrix",40,8.40336134453781,{"v":2.24830737934308e-14,"d":"2.25E-14"},"ASPN, MMP9, LUM, TNC, COL3A1, MMP7, POSTN, MMP3, MMP2, MMP1, TIMP1, LAMB3, COL7A1, TGFBI, COL6A3, LOX, LAMB1, COL11A1, COL10A1, CRISP3, COL4A2, COL4A1, LGALS1, NID2, SPARC, MMP13, ECM1, COL5A2, COL5A1, MMP12, COL4A5, MMP11, MMP10, LAMA3, BGN, COL1A2, LAMC2, VCAN, MFAP2, COL1A1",372,320,12782,4.29502688172043,{"v":8.24873502835998e-12,"d":"8.25E-12"},{"v":8.24873502835998e-12,"d":"8.25E-12"},{"v":3.10307335382731e-11,"d":"3.10E-11"}]
["GO:0048285~organelle fission",34,7.14285714285714,{"v":2.93811714023346e-14,"d":"2.94E-14"},"NEK2, AURKA, CEP55, AURKB, CCNG2, KIF2C, CDCA8, SAC3D1, NCAPG, OIP5, HELLS, ASPM, CDCA3, CDK1, CDC6, KIF11, DLGAP5, TPX2, NUSAP1, BIRC5, NDC80, CDC20, PBK, HMGA2, UBE2C, NCAPD2, CDC25B, CCNB1, MAD2L1, CCNB2, ZWINT, BUB1B, RRS1, RUVBL1",398,229,13528,5.04654275745539,{"v":7.21989135143985e-11,"d":"7.22E-11"},{"v":1.03140829210701e-11,"d":"1.03E-11"},{"v":5.17919040987635e-11,"d":"5.18E-11"}]
["GO:0022402~cell cycle process",53,11.1344537815126,{"v":1.68206206398439e-13,"d":"1.68E-13"},"PRC1, DBF4, TTK, AURKA, AURKB, KIF2C, CDCA8, OIP5, DNAJC2, ASPM, CDCA3, CDC7, CDK1, CDC6, KIF11, TPX2, NUSAP1, PBK, HMGA2, UBE2C, CDK4, NCAPD2, MAD2L1, EREG, ZWINT, BUB1B, RUVBL1, ACVR1, NEK2, CEP55, CCNG2, MLF1, RPA1, SAC3D1, NCAPG, HELLS, TRIP13, KAT2B, DLGAP5, BIRC5, NDC80, CDC20, CDKN3, RACGAP1, RAD54L, PSMB9, CDC25B, CCNB1, CCNB2, CKS2, RRS1, RAD54B, ID4",398,565,13528,3.18843776404144,{"v":4.12759826318165e-10,"d":"4.13E-10"},{"v":5.1594950534195e-11,"d":"5.16E-11"},{"v":2.96096480667529e-10,"d":"2.96E-10"}]
["GO:0031012~extracellular matrix",40,8.40336134453781,{"v":2.62897695566903e-13,"d":"2.63E-13"},"ASPN, MMP9, LUM, TNC, COL3A1, MMP7, POSTN, MMP3, MMP2, MMP1, TIMP1, LAMB3, COL7A1, TGFBI, COL6A3, LOX, LAMB1, COL11A1, COL10A1, CRISP3, COL4A2, COL4A1, LGALS1, NID2, SPARC, MMP13, ECM1, COL5A2, COL5A1, MMP12, COL4A5, MMP11, MMP10, LAMA3, BGN, COL1A2, LAMC2, VCAN, MFAP2, COL1A1",372,345,12782,3.9837930497117,{"v":9.62216972766327e-11,"d":"9.62E-11"},{"v":4.81108486383163e-11,"d":"4.81E-11"},{"v":3.61954910488293e-10,"d":"3.62E-10"}]
["GO:0044421~extracellular region part",70,14.7058823529411,{"v":1.15551212129083e-12,"d":"1.16E-12"},"ASPN, SLURP1, MMP9, IL18, MMP7, POSTN, CXCL11, MMP3, MMP2, MMP1, CXCL10, ISG15, APOE, GPX3, TGFBI, LOX, COL11A1, KLK13, COL10A1, CRISP3, LY96, MMP13, MMP12, MMP11, PTHLH, MMP10, BGN, EREG, NUCB2, COL1A2, SERPINB2, MFAP2, VCAN, LAMC2, COL1A1, CXCL1, LUM, TNC, COL3A1, ENDOU, CXCL9, APOC1, CXCL6, GREM1, ADA, TIMP1, LAMB3, COL7A1, COL6A3, PRSS3, LAMB1, SPP1, COL4A2, COL4A1, LGALS1, IL1RN, GGH, SPARC, NID2, ECM1, COL5A2, COL5A1, CCL18, COL4A5, LAMA3, APOL1, SULF1, FJX1, HSPD1, IGFBP3",372,960,12782,2.50543234767025,{"v":4.22920365394929e-10,"d":"4.23E-10"},{"v":1.40973455131643e-10,"d":"1.41E-10"},{"v":1.59088298090637e-09,"d":"1.59E-09"}]
["GO:0051301~cell division",36,7.56302521008403,{"v":1.68785861436296e-12,"d":"1.69E-12"},"CKS1B, PRC1, NEK2, CEP55, AURKB, CCNG2, CCNE2, CDCA8, SAC3D1, NCAPG, OIP5, HELLS, ASPM, CDCA3, CDC7, CDK1, CDC6, KIF11, NUSAP1, BIRC5, NDC80, CDC20, HMGA2, RACGAP1, UBE2C, CDK4, MCM5, NCAPD2, CDC25B, CCNB1, MAD2L1, CCNB2, ZWINT, CKS2, BUB1B, RUVBL1",398,295,13528,4.14792607103313,{"v":4.14203804588453e-09,"d":"4.14E-09"},{"v":4.60226412535291e-10,"d":"4.60E-10"},{"v":2.9712898808043e-09,"d":"2.97E-09"}]
["GO:0008544~epidermis development",28,5.88235294117647,{"v":4.50136658953177e-12,"d":"4.50E-12"},"COL3A1, CRABP2, FST, SPINK5, LAMB3, SPRR2C, COL7A1, PPL, SPRR2B, TGM1, TGM3, IVL, KRT13, COL5A2, COL5A1, SCEL, PTHLH, LAMA3, EVPL, EREG, ATP2C1, FLG, COL1A2, SPRR3, LAMC2, COL1A1, KLF4, EMP1",398,184,13528,5.17238365741752,{"v":1.10464336566806e-08,"d":"1.10E-08"},{"v":1.10464337677029e-09,"d":"1.10E-09"},{"v":7.92416132711082e-09,"d":"7.92E-09"}]
["GO:0005581~collagen",14,2.94117647058823,{"v":6.97763470827901e-12,"d":"6.98E-12"},"COL4A2, COL4A1, COL7A1, LUM, COL6A3, COL3A1, COL1A2, COL1A1, LOX, COL11A1, COL5A2, COL5A1, COL4A5, COL10A1",372,35,12782,13.7440860215053,{"v":2.55381649161279e-09,"d":"2.55E-09"},{"v":6.38454067392046e-10,"d":"6.38E-10"},{"v":9.60657109416729e-09,"d":"9.61E-09"}]
["GO:0044420~extracellular matrix part",22,4.62184873949579,{"v":1.82871052336262e-11,"d":"1.83E-11"},"COL4A2, COL4A1, TNC, LUM, COL3A1, SPARC, NID2, COL5A2, COL5A1, COL4A5, LAMB3, LAMA3, COL7A1, COL6A3, COL1A2, LAMC2, MFAP2, COL1A1, LOX, LAMB1, COL11A1, COL10A1",372,117,12782,6.46089513831449,{"v":6.69309674350415e-09,"d":"6.69E-09"},{"v":1.33861932649637e-09,"d":"1.34E-09"},{"v":2.51771048453974e-08,"d":"2.52E-08"}]
["GO:0007398~ectoderm development",28,5.88235294117647,{"v":2.92548157125372e-11,"d":"2.93E-11"},"COL3A1, CRABP2, FST, SPINK5, LAMB3, SPRR2C, COL7A1, PPL, SPRR2B, TGM1, TGM3, IVL, KRT13, COL5A2, COL5A1, SCEL, PTHLH, LAMA3, EVPL, EREG, ATP2C1, FLG, COL1A2, SPRR3, LAMC2, COL1A1, KLF4, EMP1",398,199,13528,4.78250549228554,{"v":7.1791327660442e-08,"d":"7.18E-08"},{"v":6.52648457499793e-09,"d":"6.53E-09"},{"v":5.14995268652285e-08,"d":"5.15E-08"}]
["GO:0032963~collagen metabolic process",12,2.52100840336134,{"v":1.66135204941851e-10,"d":"1.66E-10"},"MMP10, MMP9, COL3A1, MMP7, COL1A1, MMP3, SERPINH1, MMP13, MMP2, COL5A1, MMP1, MMP11",398,28,13528,14.5671213208901,{"v":4.07695738724456e-07,"d":"4.08E-07"},{"v":3.39746512034722e-08,"d":"3.40E-08"},{"v":2.92460711204256e-07,"d":"2.92E-07"}]
["GO:0005819~spindle",23,4.83193277310924,{"v":2.42138634375403e-10,"d":"2.42E-10"},"KIF14, CDC6, TBL1XR1, CDK1, KIF4A, KIF11, PRC1, NEK2, DLGAP5, TPX2, TTK, NUSAP1, CBX3, AURKA, CDC20, BIRC5, AURKB, RACGAP1, CDCA8, MAD2L1, SAC3D1, BUB1B, ASPM",372,147,12782,5.37608806963645,{"v":8.86227392582483e-08,"d":"8.86E-08"},{"v":1.47704570796491e-08,"d":"1.48E-08"},{"v":3.33368010974055e-07,"d":"3.33E-07"}]
["GO:0006260~DNA replication",26,5.46218487394958,{"v":3.1361065013663e-10,"d":"3.14E-10"},"DBF4, MCM10, POT1, CCNE2, RPA1, CDC45, MCM7, POLE2, DNAJC2, TOP2A, CDC7, GINS1, CDC6, GINS2, DTL, GINS4, MCM2, RNASEH2A, MCM4, MCM5, MCM6, DNA2, RFC4, RFC2, RRM2, PCNA",398,190,13528,4.65125628140703,{"v":7.69600344563414e-07,"d":"7.70E-07"},{"v":5.92000475307941e-08,"d":"5.92E-08"},{"v":5.52073231574468e-07,"d":"5.52E-07"}]
["GO:0044259~multicellular organismal macromolecule metabolic process",12,2.52100840336134,{"v":6.05070785444849e-10,"d":"6.05E-10"},"MMP10, MMP9, COL3A1, MMP7, COL1A1, MMP3, SERPINH1, MMP13, MMP2, COL5A1, MMP1, MMP11",398,31,13528,13.1573999027395,{"v":1.48484257078695e-06,"d":"1.48E-06"},{"v":1.06060256688245e-07,"d":"1.06E-07"},{"v":1.0651530102379e-06,"d":"1.07E-06"}]
["GO:0044236~multicellular organismal metabolic process",12,2.52100840336134,{"v":5.21325307658255e-09,"d":"5.21E-09"},"MMP10, MMP9, COL3A1, MMP7, COL1A1, MMP3, SERPINH1, MMP13, MMP2, COL5A1, MMP1, MMP11",398,37,13528,11.023767486079,{"v":1.27932411874143e-05,"d":"1.28E-05"},{"v":8.52887837687887e-07,"d":"8.53E-07"},{"v":9.17729336968875e-06,"d":"9.18E-06"}]
["GO:0030855~epithelial cell differentiation",20,4.2016806722689,{"v":1.83292015519792e-08,"d":"1.83E-08"},"DHRS9, EHF, SPINK5, SCEL, PTHLH, LAMA3, EVPL, RHCG, EREG, SPRR2C, FLG, PPL, UPK1A, SPRR2B, TGM1, SPRR3, TGM3, KRT4, IVL, EMP1",398,137,13528,4.96203645967061,{"v":4.49788495621161e-05,"d":"4.50E-05"},{"v":2.81123736978194e-06,"d":"2.81E-06"},{"v":3.226631055675e-05,"d":"3.23E-05"}]
["GO:0006259~DNA metabolic process",40,8.40336134453781,{"v":3.4538128700216e-08,"d":"3.45E-08"},"DBF4, PRKDC, MCM10, POT1, FANCL, CCNE2, RPA1, CDC45, MCM7, POLE2, FANCI, DNAJC2, TOP2A, HELLS, TRIP13, CDC7, GINS1, GINS2, CDC6, NUDT1, RAD51AP1, DTL, GINS4, TOPBP1, MCM2, RNASEH2A, MCM4, RAD54L, MCM5, MCM6, DNA2, RFC4, RFC2, RRM2, PCNA, DNMT1, RAD54B, RUVBL1, HSPD1, PARP1",398,506,13528,2.6869525493078,{"v":8.47529775332978e-05,"d":"8.48E-05"},{"v":4.98566811679701e-06,"d":"4.99E-06"},{"v":6.08001297863758e-05,"d":"6.08E-05"}]
["GO:0060429~epithelium development",25,5.25210084033613,{"v":5.66352167061912e-08,"d":"5.66E-08"},"JAG2, EHF, GREM1, SPINK5, HOXD11, SPRR2C, UPK1A, PPL, SPRR2B, TGM1, TGM3, KRT4, IVL, DHRS9, SCEL, FZD6, PTHLH, EVPL, LAMA3, RHCG, EREG, FLG, SPRR3, TGIF1, EMP1",398,227,13528,3.74338653620525,{"v":0.000138973168146705,"d":"1.39E-04"},{"v":7.72123829173576e-06,"d":"7.72E-06"},{"v":9.96993186119787e-05,"d":"9.97E-05"}]
["GO:0005576~extracellular region",99,20.798319327731,{"v":5.98281465952886e-08,"d":"5.98E-08"},"ASPN, MMP9, IL18, NELL2, FST, MMP7, POSTN, CXCL11, MMP3, MMP2, MMP1, CXCL10, ISG15, APOE, SERPINE1, TGFBI, LOX, COL10A1, CRISP3, CLCA4, OLFML2B, PTHLH, TMPRSS11D, TMPRSS11E, CST4, COL1A2, LAMC2, MFAP2, COL1A1, APOC1, GREM1, ADA, CALU, TIMP1, LAMB3, CDA, LAMB1, SPP1, LGALS1, IL1RN, GGH, ECM1, ACPP, LCN2, APOL1, LAMA3, FJX1, HSPD1, PDZD2, PLAU, PXDN, SLURP1, SPINK5, GPX3, KLK12, KLK11, COL11A1, CEACAM1, KLK13, LY96, MMP13, MMP12, MMP11, INHBB, MMP10, BGN, EREG, NUCB2, SERPINB2, SLPI, VCAN, CXCL1, GALNT2, TNC, LUM, COL3A1, ENDOU, CXCL9, CXCL6, PCOLCE, COL7A1, PRSS3, COL6A3, NMU, TMPRSS2, COL4A2, COL4A1, SPARC, NID2, COL5A2, COL5A1, CCL18, COL4A5, TFRC, NTS, SULF1, IGFBP3, ADAMDEC1, F2R",372,2010,12782,1.69236880115551,{"v":2.18968625518289e-05,"d":"2.19E-05"},{"v":3.12815257752507e-06,"d":"3.13E-06"},{"v":8.23692675400167e-05,"d":"8.24E-05"}]
["GO:0030199~collagen fibril organization",10,2.10084033613445,{"v":8.77607161117368e-08,"d":"8.78E-08"},"P4HA1, LUM, COL3A1, COL1A2, COL1A1, LOX, SERPINH1, COL5A2, COL11A1, COL5A1",398,29,13528,11.720672327153,{"v":0.000215341617519349,"d":"2.15E-04"},{"v":1.13349255936867e-05,"d":"1.13E-05"},{"v":0.00015449188407457,"d":"1.54E-04"}]
["GO:0009913~epidermal cell differentiation",14,2.94117647058823,{"v":1.45109296597817e-07,"d":"1.45E-07"},"SPINK5, SCEL, LAMA3, EVPL, SPRR2C, EREG, FLG, PPL, SPRR2B, TGM1, SPRR3, TGM3, IVL, KLF4",398,72,13528,6.60915689558905,{"v":0.000356034844187891,"d":"3.56E-04"},{"v":1.78047534755698e-05,"d":"1.78E-05"},{"v":0.000255446843855367,"d":"2.55E-04"}]
["GO:0005583~fibrillar collagen",7,1.47058823529411,{"v":4.57779924587358e-07,"d":"4.58E-07"},"LUM, COL3A1, COL1A2, COL1A1, COL5A2, COL11A1, COL5A1",372,12,12782,20.043458781362,{"v":0.000167533455469048,"d":"1.68E-04"},{"v":2.09432170334977e-05,"d":"2.09E-05"},{"v":0.000630253542333036,"d":"6.30E-04"}]
["GO:0000793~condensed chromosome",17,3.57142857142857,{"v":9.87085783471445e-07,"d":"9.87E-07"},"CENPN, CENPM, NEK2, CBX3, TOPBP1, NDC80, AURKB, NCAPD2, RPA1, KIF2C, MAD2L1, NCAPG, HJURP, ZWINT, BUB1B, RRS1, NUP107",372,129,12782,4.52809035592231,{"v":0.000361208323604533,"d":"3.61E-04"},{"v":4.01407026786593e-05,"d":"4.01E-05"},0.00135897660865635]
["GO:0030574~collagen catabolic process",8,1.68067226890756,{"v":9.90547514941784e-07,"d":"9.91E-07"},"MMP10, MMP9, MMP7, MMP3, MMP13, MMP2, MMP1, MMP11",398,20,13528,13.5959798994974,0.00242785279188684,{"v":0.000115745910709952,"d":"1.16E-04"},0.00174372329257987]
["GO:0005694~chromosome",34,7.14285714285714,{"v":1.55234760491868e-06,"d":"1.55E-06"},"HMGB3, NEK2, CBX3, AURKB, POT1, CITED2, RPA1, KIF2C, CDCA8, MCM7, FANCI, NCAPG, OIP5, HJURP, H2AFZ, TOP2A, HELLS, CENPN, CENPM, BIRC5, NDC80, TOPBP1, MCM2, HMGA2, NCAPD2, RFC4, MAD2L1, RFC2, ZWINT, PCNA, BUB1B, RRS1, NUP107, KLF4",372,460,12782,2.53966806919121,{"v":0.000567998292247073,"d":"5.68E-04"},{"v":5.68143524422026e-05,"d":"5.68E-05"},0.00213719669192036]
["GO:0030198~extracellular matrix organization",15,3.15126050420168,{"v":2.01242528717108e-06,"d":"2.01E-06"},"COL4A2, LUM, MMP9, COL3A1, POSTN, SERPINH1, COL5A2, SPINK5, COL5A1, P4HA1, TGFBI, COL1A2, LOX, COL1A1, COL11A1",398,104,13528,4.90239659837649,0.00492632229869105,{"v":0.000224451926166713,"d":"2.24E-04"},0.00354256916066386]
["GO:0030216~keratinocyte differentiation",12,2.52100840336134,{"v":3.04747667487125e-06,"d":"3.05E-06"},"LAMA3, EVPL, EREG, SPRR2C, FLG, PPL, TGM1, SPRR2B, SPRR3, TGM3, IVL, SCEL",398,66,13528,6.17999086340794,0.0074506246110797,{"v":0.000325100150251667,"d":"3.25E-04"},0.0053645738741781]
["GO:0005615~extracellular space",43,9.03361344537815,{"v":3.50881424031792e-06,"d":"3.51E-06"},"CXCL1, SLURP1, MMP9, IL18, ENDOU, COL3A1, APOC1, CXCL9, MMP7, CXCL6, MMP3, CXCL11, GREM1, MMP2, ADA, CXCL10, ISG15, APOE, TGFBI, COL6A3, PRSS3, GPX3, LOX, SPP1, KLK13, LY96, LGALS1, IL1RN, GGH, MMP13, CCL18, PTHLH, MMP10, APOL1, EREG, SULF1, NUCB2, COL1A2, FJX1, SERPINB2, LAMC2, HSPD1, IGFBP3",372,685,12782,2.15691860921434,0.00128340399676896,{"v":0.000116741209305604,"d":"1.17E-04"},0.00483070447830913]
["GO:0006270~DNA replication initiation",7,1.47058823529411,{"v":3.83795567439899e-06,"d":"3.84E-06"},"CCNE2, CDC45, MCM7, MCM2, MCM4, MCM5, MCM6",398,16,13528,14.8706030150753,0.00937414744999998,{"v":0.000392354729517374,"d":"3.92E-04"},0.00675603583691897]
["GO:0005856~cytoskeleton",70,14.7058823529411,{"v":4.01750665079117e-06,"d":"4.02E-06"},"PRC1, CBX3, TTK, AURKA, AURKB, SYNPO2L, KIF2C, CDC45, CDCA8, RANBP9, HOMER3, STK39, MSN, TOP2A, ASPM, KIF14, TBL1XR1, CDC6, CDK1, KIF11, LYN, CRYAB, TPX2, KRT13, NUSAP1, RAI14, TOPBP1, SCEL, EPB41L3, ARPC1B, MAD2L1, EVPL, SCIN, BUB1B, RUVBL1, ABLIM1, KIF4A, LMNB1, NEK2, SLC38A6, IGF2BP2, CEP55, KRT24, RPA1, PFN2, SPRR2C, SAC3D1, PPL, SPRR2B, KRT8, TGM1, GYS2, KRT4, TRIP10, FGD6, IVL, DLGAP5, FSCN1, KIF18B, CDC20, BIRC5, COTL1, RACGAP1, CDC25B, CCNB1, KRT75, CCNB2, FLG, TMOD3, KIF20A",372,1381,12782,1.74164739591849,0.00146932986420134,{"v":0.000122526691982205,"d":"1.23E-04"},0.00553102074305478]
["GO:0007051~spindle organization",10,2.10084033613445,{"v":5.12172158114543e-06,"d":"5.12E-06"},"KIF11, PRC1, SAC3D1, ZWINT, CKS2, BUB1B, TTK, NDC80, AURKA, UBE2C",398,45,13528,7.55332216638749,0.0124900802560947,{"v":0.000502623120538725,"d":"5.03E-04"},0.00901578045907625]
["GO:0006261~DNA-dependent DNA replication",11,2.31092436974789,{"v":6.27168240098836e-06,"d":"6.27E-06"},"RPA1, CCNE2, DNA2, CDC45, MCM7, RFC4, POLE2, MCM2, MCM4, MCM5, MCM6",398,58,13528,6.44636977993415,0.0152729244609485,{"v":0.000591777018369654,"d":"5.92E-04"},0.0110399542284977]
["GO:0044243~multicellular organismal catabolic process",8,1.68067226890756,{"v":7.21642664637482e-06,"d":"7.22E-06"},"MMP10, MMP9, MMP7, MMP3, MMP13, MMP2, MMP1, MMP11",398,26,13528,10.4584460765365,0.017553289010931,{"v":0.000655680313903284,"d":"6.56E-04"},0.0127028745924961]
["GO:0000070~mitotic sister chromatid segregation",9,1.890756302521,{"v":7.54292532613821e-06,"d":"7.54E-06"},"MAD2L1, NEK2, NCAPG, ZWINT, DLGAP5, RRS1, NUSAP1, NDC80, NCAPD2",398,36,13528,8.49748743718593,0.0183401431285753,{"v":0.000660867550842825,"d":"6.61E-04"},0.0132775651248584]
["GO:0000819~sister chromatid segregation",9,1.890756302521,{"v":9.37954978916953e-06,"d":"9.38E-06"},"MAD2L1, NEK2, NCAPG, ZWINT, DLGAP5, RRS1, NUSAP1, NDC80, NCAPD2",398,37,13528,8.26782561455928,0.022754640774079,{"v":0.000793392791499703,"d":"7.93E-04"},0.0165102634523184]
["GO:0015630~microtubule cytoskeleton",36,7.56302521008403,{"v":1.04500919561445e-05,"d":"1.05E-05"},"KIF4A, PRC1, NEK2, TTK, CBX3, AURKA, CEP55, AURKB, KIF2C, CDC45, CDCA8, RANBP9, SAC3D1, TOP2A, ASPM, KIF14, CDK1, CDC6, TBL1XR1, KIF11, CRYAB, DLGAP5, TPX2, KIF18B, NUSAP1, BIRC5, TOPBP1, CDC20, RACGAP1, CDC25B, CCNB1, MAD2L1, CCNB2, BUB1B, RUVBL1, KIF20A",372,549,12782,2.25312885598448,0.00381744858658905,{"v":0.000294168542445794,"d":"2.94E-04"},0.0143863612331873]
["GO:0007010~cytoskeleton organization",31,6.5126050420168,{"v":1.36198737075401e-05,"d":"1.36E-05"},"ABLIM1, CXCL1, PRC1, NEK2, ABLIM3, TTK, AURKA, KIF2C, RANBP9, PFN2, SAC3D1, APOE, KRT8, KRT4, TRIP10, FGD6, KIF11, CRYAB, FSCN1, NUSAP1, NDC80, RACGAP1, UBE2C, LPIN1, THY1, EPB41L3, ATP2C1, ZWINT, SCIN, CKS2, BUB1B",398,436,13528,2.41671661057581,0.0328710072911178,0.00111349286257667,0.0239734094422239]
["GO:0000775~chromosome, centromeric region",15,3.15126050420168,{"v":1.4181561055123e-05,"d":"1.42E-05"},"CENPN, CENPM, CBX3, NDC80, BIRC5, AURKB, KIF2C, CDCA8, MAD2L1, OIP5, HJURP, ZWINT, BUB1B, NUP107, HELLS",372,124,12782,4.15647762747138,0.00517704084335168,{"v":0.00037068043465982,"d":"3.71E-04"},0.0195229095779403]
["GO:0005604~basement membrane",12,2.52100840336134,{"v":1.44491710353129e-05,"d":"1.44E-05"},"LAMB3, COL4A2, LAMA3, COL4A1, COL7A1, TNC, LAMC2, NID2, SPARC, LAMB1, COL5A1, COL4A5",372,78,12782,5.28618693134822,0.00527447565262062,{"v":0.00035250017759314,"d":"3.53E-04"},0.0198912783012428]
["GO:0000779~condensed chromosome, centromeric region",11,2.31092436974789,{"v":1.86297303855166e-05,"d":"1.86E-05"},"KIF2C, CENPN, CENPM, MAD2L1, HJURP, ZWINT, BUB1B, CBX3, NDC80, NUP107, AURKB",372,66,12782,5.72670250896057,0.00679535130358777,{"v":0.000426068259323009,"d":"4.26E-04"},0.025645710851152]
["GO:0044427~chromosomal part",28,5.88235294117647,{"v":2.23332726245327e-05,"d":"2.23E-05"},"CBX3, AURKB, POT1, CITED2, RPA1, KIF2C, CDCA8, MCM7, NCAPG, OIP5, HJURP, H2AFZ, HELLS, CENPN, CENPM, BIRC5, NDC80, MCM2, HMGA2, NCAPD2, RFC4, MAD2L1, RFC2, ZWINT, PCNA, BUB1B, NUP107, KLF4",372,386,12782,2.49245083291548,0.00814075219522347,{"v":0.000480712012573603,"d":"4.81E-04"},0.0307432850260247]
["GO:0007059~chromosome segregation",12,2.52100840336134,{"v":2.31909833578733e-05,"d":"2.32E-05"},"MAD2L1, NEK2, HJURP, NCAPG, ZWINT, DLGAP5, RRS1, NUSAP1, BIRC5, NDC80, TOP2A, NCAPD2",398,81,13528,5.03554811092499,0.0553221726713257,0.00183416531327851,0.0408170280159603]
["GO:0043062~extracellular structure organization",17,3.57142857142857,{"v":2.41988586645424e-05,"d":"2.42E-05"},"COL4A2, TNC, LUM, MMP9, COL3A1, POSTN, SERPINH1, COL5A2, SPINK5, COL5A1, P4HA1, TGFBI, COL1A2, LOX, COL1A1, COL11A1, F2R",398,163,13528,3.5449640842248,0.0576558370555913,0.00185405154675033,0.0425905712019503]
["GO:0001533~cornified envelope",7,1.47058823529411,{"v":2.88843148496489e-05,"d":"2.89E-05"},"EVPL, SPRR2C, FLG, TGM1, SPRR2B, IVL, SCEL",372,22,12782,10.9327956989247,0.0105161267157789,{"v":0.000587150443868145,"d":"5.87E-04"},0.0397595822412943]
["GO:0005201~extracellular matrix structural constituent",12,2.52100840336134,{"v":3.36879785234039e-05,"d":"3.37E-05"},"COL4A2, BGN, COL4A1, LUM, COL3A1, COL1A2, COL1A1, LAMB1, COL5A2, COL11A1, COL5A1, COL4A5",374,86,12983,4.84380052232309,0.0213958374079695,0.0213958374079695,0.050203401045934]
["GO:0051726~regulation of cell cycle",25,5.25210084033613,{"v":4.40029163574731e-05,"d":"4.40E-05"},"CDC7, CKS1B, CDK1, PTPRK, CDC6, NEK2, DLGAP5, GMNN, TTK, NUSAP1, BIRC5, CDKN3, CDK4, UBE2C, CCNG2, CITED2, CCNB1, CCNE2, CDC45, MAD2L1, EREG, ZWINT, CKS2, BUB1B, HPGD",398,331,13528,2.56721674839454,0.102359417136087,0.0032669407644863,0.0774334563158896]
["GO:0042127~regulation of cell proliferation",44,9.24369747899159,{"v":5.97274692244786e-05,"d":"5.97E-05"},"CXCL1, E2F3, MARCKSL1, IL18, FOXM1, JAG2, MMP7, TTK, SOX4, CXCR2, ADA, CXCL10, TIMP1, RPA1, APOE, SERPINE1, KRT4, CD24, LAMB1, GPNMB, CDC7, ODC1, PTPRK, CDC6, KAT2B, LYN, SPARC, CDKN3, CDK4, IRS1, MMP12, CDC25B, HOXC10, PTHLH, EREG, SCIN, TGIF1, ID4, IGFBP3, PRKRIR, PLAU, KLF4, ALOX12, F2R",398,787,13528,1.90032755901489,0.13633955147487,0.00430176744849963,0.105090778428906]
["GO:0043228~non-membrane-bounded organelle",107,22.4789915966386,{"v":7.24292388525319e-05,"d":"7.24E-05"},"PRC1, CBX3, TTK, CCT2, AURKA, AURKB, CITED2, CDCA8, HOMER3, OIP5, H2AFZ, STK39, PITX1, ASPM, NCF2, CRYAB, KRT13, RAI14, TOPBP1, SCEL, NCAPD2, ARPC1B, MAD2L1, RFC4, RFC2, ZWINT, KIF4A, HMGB3, LMNB1, NEK2, SLC38A6, IGF2BP2, KRT24, PFN2, VRK1, SAC3D1, PPL, GYS2, FGD6, IVL, HELLS, FSCN1, CDC20, NDC80, FXR1, FLG, PCNA, RRS1, TMOD3, PARP1, PRKRIR, KLF4, SYNPO2L, KIF2C, CDC45, RANBP9, MCM7, FANCI, RPL39L, ZNF146, MSN, TOP2A, KIF14, TBL1XR1, CDK1, CDC6, KIF11, LYN, TPX2, NUSAP1, MCM2, HMGA2, MCM4, EPB41L3, EVPL, SCIN, BUB1B, NUP107, RUVBL1, ABLIM1, POLR2H, CEP55, POT1, RPA1, SPRR2C, NCAPG, HJURP, SPRR2B, TGM1, KRT8, KRT4, TRIP10, RBM28, CENPN, CENPM, DLGAP5, KIF18B, BIRC5, COTL1, RACGAP1, CDC25B, CCNB1, KRT75, CCNB2, HPGD, CBS, KIF20A",372,2596,12782,1.4162338254055,0.0261617544711039,0.00139429346226072,0.0996719479248287]
["GO:0043232~intracellular non-membrane-bounded organelle",107,22.4789915966386,{"v":7.24292388525319e-05,"d":"7.24E-05"},"PRC1, CBX3, TTK, CCT2, AURKA, AURKB, CITED2, CDCA8, HOMER3, OIP5, H2AFZ, STK39, PITX1, ASPM, NCF2, CRYAB, KRT13, RAI14, TOPBP1, SCEL, NCAPD2, ARPC1B, MAD2L1, RFC4, RFC2, ZWINT, KIF4A, HMGB3, LMNB1, NEK2, SLC38A6, IGF2BP2, KRT24, PFN2, VRK1, SAC3D1, PPL, GYS2, FGD6, IVL, HELLS, FSCN1, CDC20, NDC80, FXR1, FLG, PCNA, RRS1, TMOD3, PARP1, PRKRIR, KLF4, SYNPO2L, KIF2C, CDC45, RANBP9, MCM7, FANCI, RPL39L, ZNF146, MSN, TOP2A, KIF14, TBL1XR1, CDK1, CDC6, KIF11, LYN, TPX2, NUSAP1, MCM2, HMGA2, MCM4, EPB41L3, EVPL, SCIN, BUB1B, NUP107, RUVBL1, ABLIM1, POLR2H, CEP55, POT1, RPA1, SPRR2C, NCAPG, HJURP, SPRR2B, TGM1, KRT8, KRT4, TRIP10, RBM28, CENPN, CENPM, DLGAP5, KIF18B, BIRC5, COTL1, RACGAP1, CDC25B, CCNB1, KRT75, CCNB2, HPGD, CBS, KIF20A",372,2596,12782,1.4162338254055,0.0261617544711039,0.00139429346226072,0.0996719479248287]
["GO:0007155~cell adhesion",40,8.40336134453781,{"v":9.10220483399776e-05,"d":"9.10E-05"},"SLURP1, LYPD3, TNFRSF12A, TNC, PPFIA1, NELL2, COL3A1, POSTN, CRNN, CDH3, ALCAM, LAMB3, ANXA9, COL7A1, FAT1, ITGAV, TGFBI, COL6A3, MSN, CD24, LAMB1, GPNMB, COL11A1, CEACAM1, SPP1, PTPRK, GMDS, PDPN, NID2, COL5A1, THY1, AMIGO2, LAMA3, DSG2, ITGA6, ATP2C1, TROAP, VCAN, LAMC2, PDZD2",398,700,13528,1.94228284278535,0.200187755276303,0.00636191315842038,0.160112149040037]
["GO:0022610~biological adhesion",40,8.40336134453781,{"v":9.11175624179097e-05,"d":"9.11E-05"},"SLURP1, LYPD3, TNFRSF12A, TNC, PPFIA1, NELL2, COL3A1, POSTN, CRNN, CDH3, ALCAM, LAMB3, ANXA9, COL7A1, FAT1, ITGAV, TGFBI, COL6A3, MSN, CD24, LAMB1, GPNMB, COL11A1, CEACAM1, SPP1, PTPRK, GMDS, PDPN, NID2, COL5A1, THY1, AMIGO2, LAMA3, DSG2, ITGA6, ATP2C1, TROAP, VCAN, LAMC2, PDZD2",398,701,13528,1.93951211119792,0.20037521960718,0.00619221223656352,0.160280035815152]
["GO:0050840~extracellular matrix binding",7,1.47058823529411,{"v":9.58327607247807e-05,"d":"9.58E-05"},"BGN, LYPD3, ITGA6, TGFBI, SPARC, COL11A1, SPP1",374,27,12983,8.9999009704892,0.0596729894120483,0.0302954003471203,0.142752772769527]
["GO:0051276~chromosome organization",31,6.5126050420168,{"v":9.89918918780382e-05,"d":"9.90E-05"},"NEK2, EZH2, PRKDC, CBX3, HAT1, POT1, RPA1, CDCA8, NCAPG, HJURP, H2AFZ, ACTL6A, TOP2A, HELLS, TBL1XR1, KAT2B, DLGAP5, SMYD3, NUSAP1, NDC80, MCM2, HMGA2, HLTF, RAD54L, NCAPD2, MAD2L1, ZWINT, DNMT1, RRS1, RUVBL1, PARP1",398,485,13528,2.17255348909496,0.215679959746388,0.00654438694189007,0.174119967423924]
["GO:0000226~microtubule cytoskeleton organization",15,3.15126050420168,{"v":0.000107547110239452,"d":"1.08E-04"},"KIF11, PRC1, NEK2, CRYAB, NUSAP1, TTK, AURKA, NDC80, UBE2C, KIF2C, RANBP9, SAC3D1, ZWINT, CKS2, BUB1B",398,147,13528,3.46836221925956,0.231976387983964,0.00692158737402803,0.189154579236872]
["GO:0031981~nuclear lumen",67,14.0756302521008,{"v":0.000126122299234438,"d":"1.26E-04"},"NCBP2, E2F3, DBF4, EZH2, CAD, CCT2, MCM10, CCNE2, CDCA8, CDC45, MCM7, OIP5, FANCI, ZNF146, MSN, TOP2A, PITX1, CDC7, TBL1XR1, CDK1, CDC6, NCF2, TPX2, NUSAP1, TOPBP1, MCM2, CDK4, UBE2C, MCM4, TTF2, MCM5, MCM6, RFC4, RFC2, RUVBL1, SNRPG, POLR2H, CKS1B, KIF4A, LMNB1, NEK2, PRKDC, POT1, RPA1, VRK1, POLE2, HJURP, LSG1, ACTL6A, RBM28, GTF3C3, KAT2B, GMNN, CDC20, BIRC5, FXR1, CDC25B, CCNB1, DNA2, PCNA, RRS1, PARP1, HPGD, PRKRIR, KLF4, KIF20A, CBS",372,1450,12782,1.58767890248424,0.0451143393289545,0.00230552182829013,0.173501032570022]
["GO:0005654~nucleoplasm",46,9.66386554621848,{"v":0.000148051570357429,"d":"1.48E-04"},"POLR2H, NCBP2, CKS1B, E2F3, DBF4, EZH2, PRKDC, MCM10, POT1, RPA1, CCNE2, CDC45, MCM7, POLE2, OIP5, FANCI, LSG1, ACTL6A, TOP2A, GTF3C3, CDC7, TBL1XR1, CDK1, CDC6, KAT2B, GMNN, CDC20, TOPBP1, MCM2, UBE2C, CDK4, MCM4, MCM5, TTF2, CDC25B, MCM6, CCNB1, DNA2, RFC4, RFC2, PCNA, RUVBL1, PARP1, KLF4, KIF20A, SNRPG",372,882,12782,1.79202935654548,0.0527487281164464,0.00257719172322978,0.203639685082723]
["GO:0005876~spindle microtubule",7,1.47058823529411,{"v":0.000154839860917861,"d":"1.55E-04"},"CDK1, TBL1XR1, KIF4A, KIF11, PRC1, NUSAP1, BIRC5",372,29,12782,8.29384501297738,0.0550996218985293,0.00257285620123737,0.212967510874972]
["GO:0048407~platelet-derived growth factor binding",5,1.05042016806722,{"v":0.000188492035318904,"d":"1.88E-04"},"COL4A1, COL3A1, COL1A2, COL1A1, COL5A1",374,11,12983,15.7790471560525,0.113986678552679,0.0395382279959815,0.280597517937963]
["GO:0009611~response to wounding",32,6.72268907563025,{"v":0.000203196996229135,"d":"2.03E-04"},"CXCL1, TNC, COL3A1, CXCL9, CXCR2, CXCL6, CXCL11, CDH3, CXCL10, SERPINE1, MGLL, CD24, LOX, SCNN1B, BLNK, SPP1, LYN, PDPN, LY96, IL1RN, CHST2, COL5A1, CCL18, CCNB1, TFRC, EREG, SERPINB2, SPRR3, VCAN, PLAU, ACVR1, F2R",398,530,13528,2.05222338105622,0.392677967459803,0.0127056720731503,0.35710065608373]
["GO:0031424~keratinization",8,1.68067226890756,{"v":0.000229935535029231,"d":"2.30E-04"},"EVPL, SPRR2C, PPL, TGM1, SPRR2B, SPRR3, TGM3, IVL",398,43,13528,6.32371158116162,0.431257038869322,0.014009113300694,0.40400161134142]
["GO:0032964~collagen biosynthetic process",4,0.840336134453781,{"v":0.000240051547307784,"d":"2.40E-04"},"COL3A1, COL1A1, SERPINH1, COL5A1",398,5,13528,27.1919597989949,0.445205339054237,0.0142669369334039,0.421740256862357]
["GO:0048015~phosphoinositide-mediated signaling",11,2.31092436974789,{"v":0.00024824817323003,"d":"2.48E-04"},"RFC4, ZWINT, CKS2, PCNA, BUB1B, CXCR2, NDC80, AURKA, UBE2C, TOP2A, F2R",398,88,13528,4.24874371859296,0.456255953792689,0.0144018732394817,0.436111031570152]
["GO:0000777~condensed chromosome kinetochore",9,1.890756302521,{"v":0.000251774129859146,"d":"2.52E-04"},"KIF2C, CENPN, CENPM, MAD2L1, HJURP, ZWINT, BUB1B, NDC80, NUP107",372,58,12782,5.3317575083426,0.0880416272689771,0.0039989798244534,0.346077224894858]
["GO:0044430~cytoskeletal part",47,9.87394957983193,{"v":0.000423587798637475,"d":"4.24E-04"},"KIF4A, PRC1, LMNB1, NEK2, TTK, CBX3, AURKA, IGF2BP2, CEP55, AURKB, KRT24, KIF2C, RANBP9, CDCA8, CDC45, SAC3D1, HOMER3, KRT8, GYS2, KRT4, TOP2A, ASPM, KIF14, CDK1, CDC6, TBL1XR1, KIF11, LYN, CRYAB, DLGAP5, TPX2, KRT13, KIF18B, NUSAP1, CDC20, BIRC5, TOPBP1, RACGAP1, CDC25B, CCNB1, ARPC1B, KRT75, MAD2L1, FLG, BUB1B, RUVBL1, KIF20A",372,952,12782,1.69635515496521,0.143641325768467,0.00644025453161623,0.5816064931771]
["GO:0001944~vasculature development",19,3.99159663865546,{"v":0.000443439134966991,"d":"4.43E-04"},"PDPN, TNFRSF12A, IL18, COL3A1, MMP2, COL5A1, THY1, CITED2, BGN, HEY1, EREG, APOE, ITGAV, COL1A2, COL1A1, LOX, PLAU, CEACAM1, ACVR1",398,251,13528,2.57294440329135,0.663258930498747,0.0249949036931638,0.777753164884098]
["GO:0030334~regulation of cell migration",15,3.15126050420168,{"v":0.000461125376309035,"d":"4.61E-04"},"PTPRK, PDPN, MMP9, JAG2, GREM1, IRS1, ADA, CXCL10, THY1, CITED2, LAMA3, APOE, LAMB1, IGFBP3, F2R",398,169,13528,3.01685944515476,0.677567884288325,0.0253961042861052,0.808654643693085]
["GO:0001501~skeletal system development",22,4.62184873949579,{"v":0.000487949976742092,"d":"4.88E-04"},"MINPP1, CYP24A1, MMP9, COL3A1, JAG2, EN1, POSTN, SPARC, MMP13, MMP2, COL5A2, HOXD11, HOXC10, PTHLH, COL1A2, COL1A1, GPNMB, IGFBP3, COL11A1, PITX1, SPP1, COL10A1",398,319,13528,2.3441344654306,0.698118728845248,0.0262649480276848,0.855505380280019]
["GO:0007017~microtubule-based process",19,3.99159663865546,{"v":0.000492074794822097,"d":"4.92E-04"},"KIF14, KIF4A, KIF11, PRC1, CRYAB, NEK2, TTK, NUSAP1, KIF18B, AURKA, NDC80, UBE2C, KIF2C, RANBP9, SAC3D1, ZWINT, CKS2, BUB1B, KIF20A",398,253,13528,2.55260492184241,0.701160532221326,0.0259158487193303,0.86270776501619]
["GO:0008283~cell proliferation",27,5.67226890756302,{"v":0.000500013900706641,"d":"5.00E-04"},"CXCL1, STIL, CKS1B, FST, EHF, HPRT1, KIF2C, MCM7, TGFBI, ASPM, HELLS, GINS1, BST2, PDPN, DLGAP5, FSCN1, TPX2, MXD1, RACGAP1, LAMP3, EREG, CKS2, PCNA, BUB1B, ID4, HSPD1, EMP1",398,436,13528,2.10488220921119,0.706929176776414,0.0257756255019251,0.876568925582821]
["GO:0004175~endopeptidase activity",24,5.04201680672268,{"v":0.000528964345257653,"d":"5.29E-04"},"TMPRSS2, CAPN5, MMP9, MMP7, MMP3, MMP13, MMP2, MMP1, MMP12, MMP11, PSMB9, MMP10, TMPRSS11D, TMPRSS11E, FAP, PRSS3, SERPINE1, KLK12, SERPINB2, KLK11, ADAMDEC1, PLAU, PRSS21, KLK13",374,375,12983,2.22168983957219,0.288005404503415,0.0814153703072989,0.785578747772053]
["GO:0008284~positive regulation of cell proliferation",26,5.46218487394958,{"v":0.000532227913961088,"d":"5.32E-04"},"CDC7, ODC1, E2F3, LYN, MARCKSL1, IL18, TTK, SOX4, CXCR2, CDK4, IRS1, MMP12, ADA, CXCL10, CDC25B, TIMP1, HOXC10, RPA1, PTHLH, EREG, TGIF1, ID4, CD24, LAMB1, ALOX12, F2R",398,414,13528,2.13463452528342,0.729216316386203,0.0268503399983316,0.932793735240455]
["GO:0043233~organelle lumen",77,16.1764705882352,{"v":0.000541345713127025,"d":"5.41E-04"},"NCBP2, E2F3, DBF4, EZH2, CAD, CCT2, MCM10, CCNE2, CDCA8, CDC45, MCM7, P4HA1, OIP5, FANCI, ZNF146, MSN, TOP2A, PITX1, CDC7, TBL1XR1, MINPP1, CDC6, CDK1, NCF2, TPX2, NUSAP1, TOPBP1, MCM2, CDK4, UBE2C, MCM4, TTF2, MCM5, MCM6, RFC4, RFC2, RUVBL1, SNRPG, POLR2H, CKS1B, KIF4A, LMNB1, NEK2, PRKDC, SERPINH1, POT1, TIMP1, CALU, RPA1, VRK1, POLE2, HJURP, LSG1, HSPE1, ACTL6A, RBM28, GTF3C3, CES2, KAT2B, GMNN, CDC20, BIRC5, SPARC, FXR1, CDC25B, CCNB1, DNA2, PCNA, RRS1, HSPD1, PARP1, PRKRIR, HPGD, RCN1, KLF4, CBS, KIF20A",372,1820,12782,1.45370140612076,0.179782868665327,0.00789610783755512,0.742735629573565]
["GO:0051270~regulation of cell motion",16,3.36134453781512,{"v":0.000575197262776969,"d":"5.75E-04"},"PTPRK, LYN, PDPN, MMP9, JAG2, GREM1, IRS1, ADA, THY1, CITED2, CXCL10, LAMA3, APOE, LAMB1, IGFBP3, F2R",398,193,13528,2.81781966828963,0.756329942922346,0.028403909849532,1.00774357709074]
["GO:0031974~membrane-enclosed lumen",78,16.3865546218487,{"v":0.000589335233608837,"d":"5.89E-04"},"NCBP2, E2F3, DBF4, EZH2, CAD, CCT2, MCM10, CCNE2, CDCA8, CDC45, MCM7, P4HA1, OIP5, FANCI, ZNF146, MSN, TOP2A, PITX1, CDC7, TBL1XR1, MINPP1, CDC6, CDK1, LYN, NCF2, TPX2, NUSAP1, TOPBP1, MCM2, CDK4, UBE2C, MCM4, TTF2, MCM5, MCM6, RFC4, RFC2, RUVBL1, SNRPG, POLR2H, CKS1B, KIF4A, LMNB1, NEK2, PRKDC, SERPINH1, POT1, TIMP1, CALU, RPA1, VRK1, POLE2, HJURP, LSG1, HSPE1, ACTL6A, RBM28, GTF3C3, CES2, KAT2B, GMNN, CDC20, BIRC5, SPARC, FXR1, CDC25B, CCNB1, DNA2, PCNA, RRS1, HSPD1, PARP1, PRKRIR, HPGD, RCN1, KLF4, CBS, KIF20A",372,1856,12782,1.44401765850945,0.194071523554761,0.00826413500818434,0.808330606512519]
["GO:0070013~intracellular organelle lumen",75,15.7563025210084,{"v":0.000743880745653788,"d":"7.44E-04"},"NCBP2, E2F3, DBF4, EZH2, CAD, CCT2, MCM10, CCNE2, CDCA8, CDC45, MCM7, P4HA1, OIP5, FANCI, ZNF146, MSN, TOP2A, PITX1, CDC7, TBL1XR1, MINPP1, CDC6, CDK1, NCF2, TPX2, NUSAP1, TOPBP1, MCM2, CDK4, UBE2C, MCM4, TTF2, MCM5, MCM6, RFC4, RFC2, RUVBL1, SNRPG, POLR2H, CKS1B, KIF4A, LMNB1, NEK2, PRKDC, SERPINH1, POT1, CALU, RPA1, VRK1, POLE2, HJURP, LSG1, HSPE1, ACTL6A, RBM28, GTF3C3, CES2, KAT2B, GMNN, CDC20, BIRC5, FXR1, CDC25B, CCNB1, DNA2, PCNA, RRS1, HSPD1, PARP1, PRKRIR, HPGD, RCN1, KLF4, CBS, KIF20A",372,1779,12782,1.44857567680284,0.23842122722402,0.0100367613075298,1.0192996644013]
["GO:0004222~metalloendopeptidase activity",11,2.31092436974789,{"v":0.000804468339722144,"d":"8.04E-04"},"MMP10, MMP9, FAP, MMP7, MMP3, MMP13, MMP2, ADAMDEC1, MMP12, MMP1, MMP11",374,104,12983,3.6716628959276,0.403500291979118,0.0981754638445511,1.19245301833144]
["GO:0018149~peptide cross-linking",6,1.26050420168067,{"v":0.000838902668243563,"d":"8.39E-04"},"BGN, EVPL, TGM1, COL3A1, TGM3, IVL",398,26,13528,7.84383455740239,0.872486258253807,0.0403538179652527,1.46654514805186]
["GO:0001568~blood vessel development",18,3.78151260504201,{"v":0.000920102599934492,"d":"9.20E-04"},"TNFRSF12A, IL18, COL3A1, MMP2, COL5A1, THY1, CITED2, BGN, EREG, HEY1, APOE, ITGAV, COL1A2, COL1A1, LOX, PLAU, CEACAM1, ACVR1",398,245,13528,2.49722079786688,0.895542102375889,0.0433269176159832,1.60741455993872]
["GO:0060348~bone development",12,2.52100840336134,{"v":0.000983227064726015,"d":"9.83E-04"},"PTHLH, MINPP1, CYP24A1, SPARC, COL1A1, GPNMB, COL5A2, IGFBP3, MMP13, MMP2, SPP1, HOXD11",398,123,13528,3.31609265841402,0.910545590929474,0.0453624891740933,1.71679455538631]
["GO:0006297~nucleotide-excision repair, DNA gap filling",5,1.05042016806722,0.00128344940726162,"RPA1, RFC4, POLE2, RFC2, PCNA",398,17,13528,9.99704404374815,0.957216712980945,0.0577308252061201,2.2354419554207]
["GO:0000075~cell cycle checkpoint",10,2.10084033613445,0.00138256681216136,"CCNE2, CDK1, CDC6, CDC45, MAD2L1, ZWINT, BUB1B, TTK, BIRC5, CCNG2",398,91,13528,3.73515931304876,0.966465030553173,0.0609376993301582,2.40610408414698]
["GO:0005198~structural molecule activity",33,6.93277310924369,0.00140806891025954,"LMNB1, LUM, NELL2, COL3A1, KRT24, LAMB3, PPL, RPL39L, KRT8, MSN, KRT4, LAMB1, COL11A1, IVL, COL4A2, COL4A1, CRYAB, KRT13, MAL, NUP155, COL5A2, COL5A1, COL4A5, EPB41L3, ARPC1B, KRT75, LAMA3, EVPL, BGN, FLG, COL1A2, SPRR3, COL1A1",374,634,12983,1.80687511597699,0.595303255629178,0.139954122545725,2.07843720960085]
["GO:0005178~integrin binding",8,1.68067226890756,0.00144004869876595,"LYN, ITGA6, TGFBI, COL3A1, GPNMB, COL5A1, ADAMDEC1, THY1",374,59,12983,4.70696999909362,0.60353898873465,0.123806414983385,2.12517079275519]
["GO:0040012~regulation of locomotion",15,3.15126050420168,0.00160539223227552,"PTPRK, PDPN, MMP9, JAG2, GREM1, IRS1, ADA, CXCL10, THY1, CITED2, LAMA3, APOE, LAMB1, IGFBP3, F2R",398,192,13528,2.6554648241206,0.980606130234918,0.0691780267489998,2.78874354912547]
["GO:0032508~DNA duplex unwinding",5,1.05042016806722,0.00161226742766903,"MCM7, MCM2, MCM4, POT1, MCM6",398,18,13528,9.44165270798436,0.980931111976409,0.0682668994031661,2.80052721377769]
["GO:0032392~DNA geometric change",5,1.05042016806722,0.00161226742766903,"MCM7, MCM2, MCM4, POT1, MCM6",398,18,13528,9.44165270798436,0.980931111976409,0.0682668994031661,2.80052721377769]
["GO:0000776~kinetochore",9,1.890756302521,0.0017147488231011,"KIF2C, CENPN, CENPM, MAD2L1, HJURP, ZWINT, BUB1B, NDC80, NUP107",372,77,12782,4.01612903225806,0.466414933821726,0.02218369729252,2.33513627713117]
["GO:0005509~calcium ion binding",43,9.03361344537815,0.00185145178722783,"GALNT2, PXDN, GALNT6, MMP9, ANO1, NELL2, JAG2, MMP7, CRNN, MMP3, CDH3, CALB1, MMP2, MMP1, CALU, EFHD2, ANXA9, LPCAT1, SLC24A3, ITGAV, FAT1, TGM1, PRSS3, TGM3, GALNT12, EHD3, COL10A1, NID2, SPARC, MMP13, MMP12, MMP11, PTHLH, MMP10, DSG2, ITGA6, FLG, ATP2C1, SULF1, NUCB2, SCIN, VCAN, RCN1",374,919,12983,1.6242631784141,0.695697727732961,0.138186784681538,2.72452101949342]
["GO:0001503~ossification",11,2.31092436974789,0.00203840054274693,"PTHLH, MINPP1, CYP24A1, SPARC, COL1A1, GPNMB, COL5A2, IGFBP3, MMP13, MMP2, SPP1",398,115,13528,3.25121258466244,0.993311329472545,0.0840999837268917,3.52826946014832]
["GO:0031589~cell-substrate adhesion",10,2.10084033613445,0.00232062212575213,"PTPRK, LYPD3, ITGA6, TNFRSF12A, ITGAV, PPFIA1, COL3A1, NID2, LAMB1, THY1",398,98,13528,3.46836221925956,0.996658798093084,0.0936234358690785,4.00741006250369]
["GO:0030155~regulation of cell adhesion",12,2.52100840336134,0.00234766190963997,"LAMA3, ITGA6, IL18, TGFBI, JAG2, COL1A1, CD24, ADAMDEC1, ADA, ALOX12, CITED2, SPP1",398,137,13528,2.97722187580236,0.996873795280516,0.0931349432084495,4.05319873395458]
["GO:0032133~chromosome passenger complex",3,0.630252100840336,0.00247224824279698,"CDCA8, BIRC5, AURKB",372,3,12782,34.3602150537634,0.595847582786867,0.030757180155284,3.35050373986324]
["GO:0000228~nuclear chromosome",13,2.73109243697479,0.00270796905344362,"NEK2, CBX3, TOPBP1, BIRC5, MCM2, HMGA2, POT1, NCAPD2, CITED2, RPA1, MCM7, RRS1, TOP2A",372,162,12782,2.75730120801805,0.629336656324058,0.0325408094321401,3.66446590982221]
["GO:0000922~spindle pole",6,1.26050420168067,0.00278923209370086,"MAD2L1, KIF11, NEK2, DLGAP5, TPX2, ASPM",372,34,12782,6.06356736242884,0.640228188510505,0.0324391338793668,3.77248267108998]
["GO:0004866~endopeptidase inhibitor activity",12,2.52100840336134,0.00309645624950828,"COL7A1, CST4, COL6A3, SERPINE1, SERPINB2, SERPINB1, SLPI, BIRC5, SERPINB13, SERPINH1, SPINK5, TIMP1",374,145,12983,2.87287479255024,0.863442436369013,0.198462264427356,4.51750521685495]
["GO:0051329~interphase of mitotic cell cycle",10,2.10084033613445,0.00325725470244697,"CDC7, CCNB1, CDC6, DBF4, BIRC5, ID4, CDKN3, CDK4, DNAJC2, ACVR1",398,103,13528,3.29999512123725,0.999666660640686,0.124919291125506,5.581538958942]
["GO:0051325~interphase",10,2.10084033613445,0.00394803564264784,"CDC7, CCNB1, CDC6, DBF4, BIRC5, ID4, CDKN3, CDK4, DNAJC2, ACVR1",398,106,13528,3.20659903290035,0.999939183850395,0.147124662640824,6.72684909209134]
["GO:0008233~peptidase activity",29,6.09243697478991,0.00442152098396216,"MMP9, ENDOU, MMP7, MMP3, SPINK5, MMP2, MMP1, USP18, FAP, PRSS3, SERPINE1, KLK12, KLK11, KLK13, TMPRSS2, CAPN5, GGH, MMP13, MMP12, MMP11, PSMB9, MMP10, TMPRSS11D, TMPRSS11E, SERPINB2, SLPI, ADAMDEC1, PRSS21, PLAU",374,574,12983,1.75383834243231,0.941860531904934,0.247602913063872,6.39188843888334]
["GO:0030414~peptidase inhibitor activity",12,2.52100840336134,0.00466198193644561,"COL7A1, CST4, COL6A3, SERPINE1, SERPINB2, SERPINB1, SLPI, BIRC5, SERPINB13, SERPINH1, SPINK5, TIMP1",374,153,12983,2.72265911712278,0.950212473632059,0.238698976638756,6.72833281464698]
["GO:0003697~single-stranded DNA binding",7,1.47058823529411,0.00477789664197397,"RPA1, MCM7, RAD51AP1, HSPD1, MCM4, POT1, MCM6",374,55,12983,4.4181332036947,0.953799328782117,0.226036124817821,6.89011323799696]
["GO:0004252~serine-type endopeptidase activity",12,2.52100840336134,0.00489532070833205,"TMPRSS2, TMPRSS11D, FAP, TMPRSS11E, PRSS3, SERPINE1, KLK12, SERPINB2, KLK11, PRSS21, PLAU, KLK13",374,154,12983,2.70497951246614,0.957169875864261,0.215216345977413,7.05373330496847]
["GO:0004867~serine-type endopeptidase inhibitor activity",9,1.890756302521,0.00491193806256565,"COL7A1, COL6A3, SERPINE1, SERPINB2, SERPINB1, SLPI, SERPINB13, SERPINH1, SPINK5",374,92,12983,3.3959253661939,0.957626601259237,0.202124305058624,7.07686644283315]
["GO:0007346~regulation of mitotic cell cycle",12,2.52100840336134,0.00520512891159864,"CDK1, CDC6, MAD2L1, EREG, NEK2, ZWINT, DLGAP5, BUB1B, NUSAP1, TTK, BIRC5, UBE2C",398,152,13528,2.68341708542713,0.999997257788155,0.186622880082758,8.77755626894026]
["GO:0070330~aromatase activity",5,1.05042016806722,0.00525753145397165,"CYP3A5, CYP2J2, CYP2C18, CYP4F12, CYP4B1",374,25,12983,6.9427807486631,0.966096579907602,0.201975482883157,7.55675373793051]
["GO:0008236~serine-type peptidase activity",13,2.73109243697479,0.00533987985003244,"TMPRSS2, ENDOU, TMPRSS11D, FAP, TMPRSS11E, SERPINE1, PRSS3, KLK12, SERPINB2, KLK11, PRSS21, PLAU, KLK13",374,178,12983,2.53528510484888,0.967851473930025,0.193326915204128,7.67076024077612]
["GO:0051184~cofactor transporter activity",4,0.840336134453781,0.00542895316325182,"SLC25A32, SLC33A1, PDPN, SLC6A8",374,13,12983,10.6812011517893,0.969647710173396,0.18582615874637,7.79392931528502]
["GO:0003678~DNA helicase activity",6,1.26050420168067,0.00548553473095516,"DNA2, MCM7, RAD54B, RUVBL1, MCM4, MCM6",374,40,12983,5.20708556149732,0.97073631664286,0.178143385253265,7.87208972178568]
["GO:0048730~epidermis morphogenesis",5,1.05042016806722,0.00566886341787987,"FST, COL1A2, TGM3, COL1A1, KLF4",398,25,13528,6.79798994974874,0.999999126686614,0.198639194891513,9.52325516793503]
["GO:0001556~oocyte maturation",4,0.840336134453781,0.00576154908008714,"CCNB1, EREG, TRIP13, CDC25B",398,13,13528,10.4584460765365,0.999999305260849,0.19873077047941,9.67160541214123]
["GO:0017171~serine hydrolase activity",13,2.73109243697479,0.0058287861128192,"TMPRSS2, ENDOU, TMPRSS11D, FAP, TMPRSS11E, SERPINE1, PRSS3, KLK12, SERPINB2, KLK11, PRSS21, PLAU, KLK13",374,180,12983,2.50711527035056,0.976553384978503,0.179242717490279,8.3449255807256]
["GO:0044432~endoplasmic reticulum part",20,4.2016806722689,0.00611557948835183,"SOAT1, TM7SF2, MINPP1, CYP3A5, CES2, TUSC3, CYP2C18, SLC33A1, PGAP1, DHRS9, CYP4F12, SERPINH1, SPINK5, TMEM38B, CYP4B1, CALU, P4HA1, FMO2, ERO1L, RCN1",372,347,12782,1.98041585324284,0.894090929971615,0.0677569354887164,8.09876061572754]
["GO:0030336~negative regulation of cell migration",7,1.47058823529411,0.00631555281197003,"PTPRK, APOE, GREM1, IGFBP3, ADA, CITED2, THY1",398,57,13528,4.17420435510887,0.999999823070416,0.212736698752573,10.5535563274959]
["GO:0000302~response to reactive oxygen species",8,1.68067226890756,0.00635808363527883,"PTPRK, PXDN, APOE, CRYAB, GPX3, SERPINE1, COL1A1, ADA",398,75,13528,3.62559463986599,0.999999840711729,0.211134823963887,10.6209268463186]
["GO:0006974~response to DNA damage stimulus",21,4.41176470588235,0.00708608099893789,"CDK1, NUDT1, RAD51AP1, LYN, DTL, PRKDC, TOPBP1, RAD54L, RPA1, FANCL, DNA2, RFC4, MCM7, POLE2, FANCI, RFC2, PCNA, RAD54B, PARP1, TOP2A, TRIP13",398,373,13528,1.91364328344133,0.99999997363283,0.229306768278991,11.7667089852233]
["GO:0004386~helicase activity",11,2.31092436974789,0.00714412357650596,"DNA2, MCM7, DDX60, RAD54B, RUVBL1, HLTF, RAD54L, MCM4, HELLS, TTF2, MCM6",374,140,12983,2.72752100840336,0.989978165792904,0.205585137449403,10.1359506643001]
["GO:0006268~DNA unwinding during replication",4,0.840336134453781,0.00717501618836808,"MCM7, MCM2, MCM4, MCM6",398,14,13528,9.71141421392677,0.999999978835922,0.228845908809389,11.9057290321503]
["GO:0001649~osteoblast differentiation",6,1.26050420168067,0.00739410654717413,"PTHLH, CYP24A1, COL1A1, GPNMB, IGFBP3, SPP1",398,42,13528,4.85570710696338,0.999999987686301,0.231988100033751,12.2473217596357]
["GO:0006954~inflammatory response",19,3.99159663865546,0.00757151908186577,"CXCL1, LYN, PDPN, LY96, IL1RN, CXCL9, CHST2, CXCR2, CXCL6, CXCL11, CCL18, CXCL10, TFRC, MGLL, CD24, F2R, SPP1, BLNK, ACVR1",398,325,13528,1.98710475454194,0.999999992058838,0.233902477657308,12.5230170584263]
["GO:0070482~response to oxygen levels",11,2.31092436974789,0.008659128032799,"TFRC, PDPN, IL18, JAG2, CD24, SCNN1B, MMP13, MMP2, ADA, PLAU, CITED2",398,141,13528,2.6516982073488,0.999999999461393,0.25962025392174,14.1953643807583]
["GO:0070011~peptidase activity, acting on L-amino acid peptides",27,5.67226890756302,0.00868709322054649,"TMPRSS2, CAPN5, MMP9, ENDOU, MMP7, GGH, MMP3, MMP13, MMP2, MMP1, MMP12, PSMB9, MMP11, MMP10, USP18, TMPRSS11D, FAP, TMPRSS11E, SERPINE1, PRSS3, KLK12, SERPINB2, KLK11, PLAU, PRSS21, ADAMDEC1, KLK13",374,549,12983,1.70724116770404,0.99630760328453,0.234125621770776,12.1953015870128]
["GO:0040013~negative regulation of locomotion",7,1.47058823529411,0.00876571441573609,"PTPRK, APOE, GREM1, IGFBP3, ADA, CITED2, THY1",398,61,13528,3.90048603674108,0.999999999586307,0.259242459065566,14.3576229659915]
["GO:0007052~mitotic spindle organization",4,0.840336134453781,0.00877598332390895,"KIF11, PRC1, TTK, NDC80",398,15,13528,9.06398659966499,0.999999999596692,0.256450144331746,14.3732402369042]
["GO:0006275~regulation of DNA replication",7,1.47058823529411,0.00947154452553884,"DNA2, CDC6, CDC45, EREG, GMNN, PCNA, POT1",398,62,13528,3.83757497163235,0.99999999992797,0.270644379745228,15.4248405634021]
["GO:0051340~regulation of ligase activity",8,1.68067226890756,0.00959906683538649,"CCNB1, CDK1, MAD2L1, BUB1B, CDC20, UBE2C, GCLM, PSMB9",398,81,13528,3.35703207394999,0.999999999947483,0.270647867081447,15.6163118943925]
["GO:0043588~skin development",5,1.05042016806722,0.00970834609498862,"COL3A1, COL1A2, COL1A1, COL5A2, COL5A1",398,29,13528,5.8603361635765,0.999999999959941,0.270217679294614,15.7800664000688]
["GO:0006281~DNA repair",17,3.57142857142857,0.00982541227701687,"RAD51AP1, NUDT1, PRKDC, TOPBP1, RAD54L, RPA1, FANCL, DNA2, RFC4, POLE2, FANCI, RFC2, PCNA, RAD54B, PARP1, TOP2A, TRIP13",398,284,13528,2.0346096680586,0.999999999970029,0.269981693411023,15.9551570259169]
["GO:0008009~chemokine activity",6,1.26050420168067,0.00993746365275723,"CXCL1, CXCL9, CXCL6, CXCL11, CCL18, CXCL10",374,46,12983,4.52790048825854,0.998357873162308,0.252815976310039,13.8317443371458]
["GO:0016712~oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen",5,1.05042016806722,0.0101784503883145,"CYP3A5, CYP2J2, CYP2C18, CYP4F12, CYP4B1",374,30,12983,5.78565062388591,0.998595464199481,0.24841225943363,14.143850880693]
["GO:0051271~negative regulation of cell motion",7,1.47058823529411,0.0102169972425245,"PTPRK, APOE, GREM1, IGFBP3, ADA, CITED2, THY1",398,63,13528,3.77666108319374,0.999999999988646,0.276095507148665,16.5383413852632]
["GO:0032403~protein complex binding",13,2.73109243697479,0.0111162564068595,"LAMB3, LYN, ITGA6, TGFBI, COL3A1, PCNA, FCGR2A, GPNMB, IRS1, COL5A1, ADAMDEC1, ACVR1, THY1",374,196,12983,2.30245279930153,0.99923573761207,0.258459110411091,15.3484116365673]
["GO:0005587~collagen type IV",3,0.630252100840336,0.0116643736759841,"COL4A2, COL4A1, COL4A5",372,6,12782,17.1801075268817,0.986353260299895,0.122017773180436,14.9163214449673]
["GO:0005663~DNA replication factor C complex",3,0.630252100840336,0.0116643736759841,"RFC4, RFC2, PCNA",372,6,12782,17.1801075268817,0.986353260299895,0.122017773180436,14.9163214449673]
["GO:0031145~anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process",7,1.47058823529411,0.0118312643894707,"CCNB1, CDK1, MAD2L1, BUB1B, CDC20, UBE2C, PSMB9",398,65,13528,3.66045612678778,0.999999999999793,0.309064922134443,18.9023991614956]
["GO:0009628~response to abiotic stimulus",20,4.2016806722689,0.0124143934232356,"PTPRK, LYN, CRYAB, IL18, COL3A1, PRKDC, TOPBP1, CRNN, SNAI2, RAD54L, MMP13, SPRR2C, HSPB8, RAD54B, COL1A1, ERO1L, SERPINB13, COL11A1, IVL, NMU",398,368,13528,1.84727987764911,0.999999999999951,0.318320066786312,19.7407408949604]
["GO:0042379~chemokine receptor binding",6,1.26050420168067,0.0128947937763186,"CXCL1, CXCL9, CXCL6, CXCL11, CCL18, CXCL10",374,49,12983,4.25068209101822,0.999759380912672,0.283438941066596,17.5896597911315]
["GO:0006800~oxygen and reactive oxygen species metabolic process",7,1.47058823529411,0.0136173193694425,"PXDN, NCF2, CRYAB, FMO2, GPX3, CD24, ALOX12",398,67,13528,3.55118877971949,0.999999999999997,0.339916573375827,21.4443859423251]
["GO:0030496~midbody",4,0.840336134453781,0.0143156085098506,"CDK1, NEK2, BIRC5, AURKB",372,18,12782,7.63560334528076,0.994894198982156,0.14377064271448,18.005387944635]
["GO:0007160~cell-matrix adhesion",8,1.68067226890756,0.015610535605632,"PTPRK, LYPD3, ITGA6, ITGAV, PPFIA1, COL3A1, NID2, THY1",398,89,13528,3.05527638190954,1,0.37553415895837,24.1924183592165]
["GO:0030935~sheet-forming collagen",3,0.630252100840336,0.0160188179699571,"COL4A2, COL4A1, COL4A5",372,7,12782,14.7258064516129,0.997288770942474,0.155378967828918,19.9346477554662]
["GO:0033554~cellular response to stress",27,5.67226890756302,0.0161604008868806,"PXDN, PRKDC, RPA1, FANCL, MCM7, POLE2, FANCI, GPX3, ERO1L, TOP2A, TRIP13, PTPRK, CDK1, RAD51AP1, NUDT1, LYN, CRYAB, DTL, TOPBP1, RAD54L, DNA2, RFC4, RFC2, PCNA, RAD54B, VCAN, PARP1",398,566,13528,1.62142869826162,1,0.382271070087299,24.9344032055325]
["GO:0000725~recombinational repair",4,0.840336134453781,0.0171398670402594,"RPA1, RAD51AP1, RAD54B, RAD54L",398,19,13528,7.15577889447236,1,0.39653658388721,26.2391499573013]
["GO:0000724~double-strand break repair via homologous recombination",4,0.840336134453781,0.0171398670402594,"RPA1, RAD51AP1, RAD54B, RAD54L",398,19,13528,7.15577889447236,1,0.39653658388721,26.2391499573013]
["GO:0001666~response to hypoxia",10,2.10084033613445,0.0172404525133727,"TFRC, IL18, JAG2, CD24, SCNN1B, MMP13, MMP2, ADA, PLAU, CITED2",398,134,13528,2.53656341408535,1,0.39473119627274,26.3719219098743]
["GO:0048729~tissue morphogenesis",12,2.52100840336134,0.0172481856567696,"FST, COL1A2, JAG2, TGIF1, TGM3, COL1A1, GREM1, COL11A1, KLF4, FZD6, HOXD11, ACVR1",398,180,13528,2.26599664991624,1,0.39132388420849,26.3821202551899]
["GO:0051439~regulation of ubiquitin-protein ligase activity during mitotic cell cycle",7,1.47058823529411,0.0177383012602109,"CCNB1, CDK1, MAD2L1, BUB1B, CDC20, UBE2C, PSMB9",398,71,13528,3.35112180621416,1,0.396393767352297,27.0257656134343]
["GO:0032844~regulation of homeostatic process",9,1.890756302521,0.0190005362545217,"LYN, CD24, GCLM, POT1, ADA, IFI6, F2R, SPP1, THY1",398,114,13528,2.68341708542713,1,0.414303956838675,28.6590488965398]
["GO:0010564~regulation of cell cycle process",9,1.890756302521,0.0190005362545217,"CDC7, MAD2L1, EREG, NEK2, DLGAP5, NUSAP1, TTK, BIRC5, UBE2C",398,114,13528,2.68341708542713,1,0.414303956838675,28.6590488965398]
["GO:0005518~collagen binding",5,1.05042016806722,0.019131249801706,"MMP9, LUM, NID2, SPARC, SERPINH1",374,36,12983,4.82137551990493,0.999995886639311,0.379340048971511,25.0187978055137]
["GO:0030193~regulation of blood coagulation",5,1.05042016806722,0.0205183162077917,"PDPN, APOE, SERPINE1, PLAU, F2R",398,36,13528,4.72082635399218,1,0.435399570396622,30.5773446009079]
["GO:0042476~odontogenesis",6,1.26050420168067,0.0206871339334836,"ITGA6, FST, COL1A2, JAG2, COL1A1, LAMB1",398,54,13528,3.77666108319374,1,0.434466309096722,30.7876776272644]
["GO:0043094~cellular metabolic compound salvage",3,0.630252100840336,0.0213940557201968,"CDA, HPRT1, ADA",398,8,13528,12.7462311557788,1,0.441887735603012,31.6619333999749]
["GO:0006323~DNA packaging",9,1.890756302521,0.0218482105530167,"HJURP, NCAPG, H2AFZ, HAT1, NUSAP1, MCM2, TOP2A, HELLS, NCAPD2",398,117,13528,2.61461151913413,1,0.445250081267933,32.2180837124676]
["GO:0031214~biomineral formation",5,1.05042016806722,0.0224879445349767,"MINPP1, COL1A1, GPNMB, MMP13, SPP1",398,37,13528,4.59323645253293,1,0.451279125773852,32.9942529050583]
["GO:0048599~oocyte development",4,0.840336134453781,0.0225332910047933,"CCNB1, EREG, TRIP13, CDC25B",398,21,13528,6.47427614261785,1,0.448432883260878,33.0489509739938]
["GO:0008094~DNA-dependent ATPase activity",6,1.26050420168067,0.0235380753985508,"DNA2, RFC4, RFC2, RAD54B, TOP2A, TTF2",374,57,12983,3.65409513087531,0.999999771592052,0.432420970438392,29.8863574899065]
["GO:0045121~membrane raft",10,2.10084033613445,0.0235620935335922,"EFHD2, MALL, LYN, ATP1B3, MAL, FADD, CD24, IRS1, F2R, THY1",372,143,12782,2.40281224152191,0.999837843296366,0.215269714122563,27.9836840194293]
["GO:0051783~regulation of nuclear division",6,1.26050420168067,0.0238373924471385,"MAD2L1, EREG, NEK2, DLGAP5, NUSAP1, TTK",398,56,13528,3.64178033022254,1,0.463782419122294,34.6040895076648]
["GO:0000082~G1/S transition of mitotic cell cycle",6,1.26050420168067,0.0238373924471385,"CDC7, DBF4, ID4, CDKN3, CDK4, ACVR1",398,56,13528,3.64178033022254,1,0.463782419122294,34.6040895076648]
["GO:0007088~regulation of mitosis",6,1.26050420168067,0.0238373924471385,"MAD2L1, EREG, NEK2, DLGAP5, NUSAP1, TTK",398,56,13528,3.64178033022254,1,0.463782419122294,34.6040895076648]
["GO:0043123~positive regulation of I-kappaB kinase/NF-kappaB cascade",8,1.68067226890756,0.0239071805027764,"BST2, SLC20A1, ATP2C1, LGALS1, FADD, ECM1, ECT2, F2R",398,97,13528,2.80329482463865,1,0.461275529886334,34.6863436173166]
["GO:0043566~structure-specific DNA binding",10,2.10084033613445,0.0240827141459469,"RPA1, HLF, MCM7, RAD51AP1, PCNA, HSPD1, MCM4, KLF4, POT1, MCM6",374,145,12983,2.3940623271252,0.999999840355954,0.428185117501446,30.467031223114]
["GO:0004857~enzyme inhibitor activity",15,3.15126050420168,0.0242153468335623,"ANP32E, APOC1, BIRC5, SERPINH1, SPINK5, POT1, TIMP1, COL7A1, CST4, COL6A3, SERPINE1, SERPINB2, SERPINB1, SLPI, SERPINB13",374,270,12983,1.92855020796197,0.999999853695618,0.41880854779528,30.6077583763989]
["GO:0051327~M phase of meiotic cell cycle",8,1.68067226890756,0.0251224701769621,"RPA1, EREG, NEK2, CKS2, RAD54B, RAD54L, TRIP13, CDC25B",398,98,13528,2.77468977540765,1,0.47465098949899,36.1031659393852]
["GO:0007126~meiosis",8,1.68067226890756,0.0251224701769621,"RPA1, EREG, NEK2, CKS2, RAD54B, RAD54L, TRIP13, CDC25B",398,98,13528,2.77468977540765,1,0.47465098949899,36.1031659393852]
["GO:0005125~cytokine activity",12,2.52100840336134,0.0252821780797557,"INHBB, CXCL1, SLURP1, IL18, IL1RN, CXCL9, CXCL6, CXCL11, GREM1, CCL18, SPP1, CXCL10",374,195,12983,2.13624023035787,0.999999927513321,0.421892495901273,31.7300718166594]
["GO:0042060~wound healing",12,2.52100840336134,0.025459159330442,"CCNB1, EREG, SERPINE1, COL3A1, SPRR3, SERPINB2, LOX, CDH3, SCNN1B, COL5A1, PLAU, F2R",398,191,13528,2.13549422505196,1,0.475743334563624,36.4905301402308]
["GO:0009994~oocyte differentiation",4,0.840336134453781,0.0255364804580276,"CCNB1, EREG, TRIP13, CDC25B",398,22,13528,6.17999086340794,1,0.473349270026614,36.5791755827046]
["GO:0048286~lung alveolus development",4,0.840336134453781,0.0255364804580276,"PTHLH, PDPN, HOPX, ADA",398,22,13528,6.17999086340794,1,0.473349270026614,36.5791755827046]
["GO:0022407~regulation of cell-cell adhesion",4,0.840336134453781,0.0255364804580276,"ITGA6, CD24, ADA, CITED2",398,22,13528,6.17999086340794,1,0.473349270026614,36.5791755827046]
["GO:0045596~negative regulation of cell differentiation",13,2.73109243697479,0.0258517387111509,"PTHLH, HMGB3, EREG, ITGAV, FST, EZH2, HOPX, ID4, CD24, KLF4, ASPM, SPP1, THY1",398,216,13528,2.04569142006327,1,0.474153527003206,36.9393995023922]
["GO:0043256~laminin complex",3,0.630252100840336,0.0264276181398636,"LAMA3, LAMC2, LAMB1",372,9,12782,11.4534050179211,0.999944693290908,0.232744622434135,30.8395083025797]
["GO:0051262~protein tetramerization",5,1.05042016806722,0.0267624535699938,"GPX3, CDA, TGM3, ADSL, HPRT1",398,39,13528,4.35768586522355,1,0.482687259484348,37.9692019451808]
["GO:0051438~regulation of ubiquitin-protein ligase activity",7,1.47058823529411,0.0268692813620197,"CCNB1, CDK1, MAD2L1, BUB1B, CDC20, UBE2C, PSMB9",398,78,13528,3.05038010565648,1,0.480706894316946,38.0889539750386]
["GO:0051321~meiotic cell cycle",8,1.68067226890756,0.0276786143744513,"RPA1, EREG, NEK2, CKS2, RAD54B, RAD54L, TRIP13, CDC25B",398,100,13528,2.71919597989949,1,0.487650367212884,38.9891437455347]
["GO:0009967~positive regulation of signal transduction",16,3.36134453781512,0.0278978080984281,"BST2, SLC20A1, LYN, LGALS1, SOX4, TTK, FADD, ECT2, ECM1, IRS1, ADA, CITED2, EREG, ATP2C1, CD24, F2R",398,295,13528,1.84352269823694,1,0.487081185250784,39.2308114547]
["GO:0009954~proximal/distal pattern formation",4,0.840336134453781,0.0287436181839763,"HOXC10, EN1, GREM1, HOXD11",398,23,13528,5.91129560847716,1,0.494204678348734,40.1549051699973]
["GO:0009112~nucleobase metabolic process",4,0.840336134453781,0.0287436181839763,"CDA, CAD, HPRT1, ADA",398,23,13528,5.91129560847716,1,0.494204678348734,40.1549051699973]
["GO:0043161~proteasomal ubiquitin-dependent protein catabolic process",8,1.68067226890756,0.0304058790276104,"CCNB1, CDK1, TBL1XR1, MAD2L1, BUB1B, CDC20, UBE2C, PSMB9",398,102,13528,2.66587841166617,1,0.510733775309917,41.9325303911351]
["GO:0010498~proteasomal protein catabolic process",8,1.68067226890756,0.0304058790276104,"CCNB1, CDK1, TBL1XR1, MAD2L1, BUB1B, CDC20, UBE2C, PSMB9",398,102,13528,2.66587841166617,1,0.510733775309917,41.9325303911351]
["GO:0005813~centrosome",13,2.73109243697479,0.0304487351973006,"NEK2, DLGAP5, AURKA, TOPBP1, BIRC5, CEP55, CDC25B, CCNB1, CDC45, SAC3D1, BUB1B, RUVBL1, TOP2A",372,224,12782,1.99411962365591,0.999987840814859,0.257570225055844,34.6702254459189]
["GO:0050818~regulation of coagulation",5,1.05042016806722,0.0314910211059989,"PDPN, APOE, SERPINE1, PLAU, F2R",398,41,13528,4.14511582301752,1,0.519942689197109,43.0659872020175]
["GO:0000910~cytokinesis",5,1.05042016806722,0.0314910211059989,"PRC1, NUSAP1, BIRC5, AURKB, RACGAP1",398,41,13528,4.14511582301752,1,0.519942689197109,43.0659872020175]
["GO:0005815~microtubule organizing center",14,2.94117647058823,0.0335194307697171,"NEK2, DLGAP5, AURKA, BIRC5, TOPBP1, CEP55, CDC25B, CCNB1, CDC45, MAD2L1, SAC3D1, BUB1B, RUVBL1, TOP2A",372,253,12782,1.90135577372604,0.999996192108888,0.273821823958149,37.4619760617518]
["GO:0010647~positive regulation of cell communication",17,3.57142857142857,0.0336851941118969,"BST2, SLC20A1, LYN, LGALS1, SOX4, TTK, FADD, ECT2, ECM1, IRS1, ADA, CITED2, EREG, ATP2C1, CD24, NMU, F2R",398,329,13528,1.75631959188037,1,0.540947569122726,45.2944022759888]
["GO:0001871~pattern binding",10,2.10084033613445,0.0337079315820425,"BGN, APOE, ZNF146, ENDOU, LAMC2, VCAN, POSTN, CXCL6, GPNMB, COL5A1",374,154,12983,2.25414959372178,0.999999999724829,0.508413357987734,40.017212163299]
["GO:0030247~polysaccharide binding",10,2.10084033613445,0.0337079315820425,"BGN, APOE, ZNF146, ENDOU, LAMC2, VCAN, POSTN, CXCL6, GPNMB, COL5A1",374,154,12983,2.25414959372178,0.999999999724829,0.508413357987734,40.017212163299]
["GO:0006310~DNA recombination",8,1.68067226890756,0.0348266378009281,"RPA1, RAD51AP1, PRKDC, RAD54B, RUVBL1, HSPD1, RAD54L, TRIP13",398,105,13528,2.58971045704714,1,0.549797386997955,46.4208728400305]
["GO:0002683~negative regulation of immune system process",7,1.47058823529411,0.0350164354980264,"HMGB3, COL3A1, CD24, GREM1, SPINK5, ADA, THY1",398,83,13528,2.86662226796633,1,0.548504515696116,46.6060460771434]
["GO:0006302~double-strand break repair",6,1.26050420168067,0.0350793666902172,"RPA1, RAD51AP1, PRKDC, RAD54B, RAD54L, TRIP13",398,62,13528,3.28934997568487,1,0.545913630173501,46.6673105694831]
["GO:0030261~chromosome condensation",4,0.840336134453781,0.035765291660338,"NCAPG, NUSAP1, TOP2A, NCAPD2",398,25,13528,5.43839195979899,1,0.549771505605724,47.3307835807003]
["GO:0045177~apical part of cell",11,2.31092436974789,0.0360565409246713,"EPCAM, RHCG, CLCA4, PDPN, STK39, MAL, MSN, SCNN1B, FZD6, SPP1, ACVR1",372,179,12782,2.11152159548266,0.999998544972405,0.285385571302434,39.6847033716598]
["GO:0007093~mitotic cell cycle checkpoint",5,1.05042016806722,0.0366795690135356,"CDK1, MAD2L1, ZWINT, BUB1B, TTK",398,43,13528,3.95231973822601,1,0.555826283163248,48.2030369016365]
["GO:0006029~proteoglycan metabolic process",5,1.05042016806722,0.0366795690135356,"BGN, CHST12, SULF1, CSGALNACT2, COL11A1",398,43,13528,3.95231973822601,1,0.555826283163248,48.2030369016365]
["GO:0042175~nuclear envelope-endoplasmic reticulum network",15,3.15126050420168,0.0378351126522808,"SOAT1, TM7SF2, CYP3A5, TUSC3, CYP2C18, SLC33A1, PGAP1, DHRS9, CYP4F12, SPINK5, TMEM38B, CYP4B1, FMO2, NUCB2, ERO1L",372,284,12782,1.81480009086778,0.999999259852192,0.291285722683555,41.1989567793396]
["GO:0043122~regulation of I-kappaB kinase/NF-kappaB cascade",8,1.68067226890756,0.0379991724142821,"BST2, SLC20A1, ATP2C1, LGALS1, FADD, ECM1, ECT2, F2R",398,107,13528,2.54130465411167,1,0.565660497000536,49.437991399064]
["GO:0008237~metallopeptidase activity",11,2.31092436974789,0.0386434590086872,"MMP10, MMP9, FAP, MMP7, MMP3, MMP13, MMP2, ADAMDEC1, MMP12, MMP1, MMP11",374,183,12983,2.08662809386049,0.999999999989723,0.54645540948269,44.4253354211445]
["GO:0022409~positive regulation of cell-cell adhesion",3,0.630252100840336,0.039657670632678,"ITGA6, CD24, CITED2",398,11,13528,9.26998629511192,1,0.578315483431015,50.9507343367185]
["GO:0002244~hemopoietic progenitor cell differentiation",3,0.630252100840336,0.039657670632678,"PRKDC, SOX4, MLF1",398,11,13528,9.26998629511192,1,0.578315483431015,50.9507343367185]
["GO:0032269~negative regulation of cellular protein metabolic process",11,2.31092436974789,0.0397184779076995,"MAD2L1, ITGAV, BUB1B, DNMT1, CDC20, IGF2BP2, UBE2C, IGFBP3, PAIP2B, PSMB9, TIMP1",398,180,13528,2.07716359575656,1,0.575733482152406,51.005377965244]
["GO:0001882~nucleoside binding",59,12.3949579831932,0.0398283712647046,"TTK, AURKA, CCT2, CAD, AURKB, HSPH1, KIF2C, MCM7, CHST12, DDX60, STK39, TOP2A, CDC7, KIF14, CDK1, CDC6, KIF11, LYN, TPX2, CCT6A, MCM2, PBK, UBE2C, HLTF, CDK4, MCM4, TTF2, MCM5, MCM6, RFC4, RFC2, ATP2C1, BUB1B, RUVBL1, MELK, ACVR1, ABCA8, KIF4A, NEK2, PRKDC, ADA, VRK1, FMO2, PTK6, TGM3, CDA, ACTL6A, HSPE1, ERO1L, EHD3, HELLS, TRIP13, KIF18B, ATAD2, RAD54L, DNA2, RAD54B, HSPD1, KIF20A",374,1612,12983,1.27054610474914,0.999999999995344,0.546470778718526,45.4376615018737]
["GO:0010605~negative regulation of macromolecule metabolic process",31,6.5126050420168,0.0406902642639906,"FST, CBX3, HAT1, IGF2BP2, POT1, TIMP1, CITED2, PAIP2B, CDC45, HEY1, ITGAV, HELLS, CDC6, PTPRK, TBL1XR1, GMNN, UPK3B, CDC20, SNAI2, UBE2C, PSMB9, INHBB, MAD2L1, EREG, HOPX, BUB1B, TGIF1, DNMT1, ID4, IGFBP3, KLF4",398,734,13528,1.4355428367998,1,0.581593439252187,51.8709070914097]
["GO:0048589~developmental growth",7,1.47058823529411,0.0425700459633423,"CCNB1, GINS1, EREG, SERPINE1, SPINK5, PLAU, HOXD11",398,87,13528,2.73482354300236,1,0.595340383694069,53.5043790447709]
["GO:0033273~response to vitamin",6,1.26050420168067,0.0441263950733428,"CYP24A1, TFRC, AQP3, KLF4, SPP1, MEST",398,66,13528,3.08999543170397,1,0.605704842201322,54.8170837988842]
["GO:0001775~cell activation",15,3.15126050420168,0.0441407798429579,"SLURP1, BST2, LYN, COL3A1, JAG2, SOX4, PRKDC, CXCR2, HPRT1, ADA, CD24, HSPD1, HELLS, F2R, BLNK",398,287,13528,1.77647820986465,1,0.602757282770589,54.8290519832153]
["GO:0040008~regulation of growth",17,3.57142857142857,0.0441633177491525,"TMEM97, TNFRSF12A, CRYAB, FOXM1, NELL2, GREM1, HMGA2, APOE, HOPX, CDA, ACTL6A, RUVBL1, PARP1, DNAJC2, IGFBP3, SPP1, ALOX12",398,341,13528,1.69451362383766,1,0.59990617421842,54.8477975966154]
["GO:0019932~second-messenger-mediated signaling",13,2.73109243697479,0.0448405486689693,"PTHLH, RFC4, APOE, ZWINT, CKS2, PCNA, BUB1B, CXCR2, NDC80, AURKA, UBE2C, TOP2A, F2R",398,235,13528,1.88029509248369,1,0.602596970756315,55.4076650280847]
["GO:0032101~regulation of response to external stimulus",10,2.10084033613445,0.0448626094440228,"PDPN, APOE, SERPINE1, HOPX, CD24, GREM1, ADA, PLAU, F2R, SPP1",398,159,13528,2.13773268860023,1,0.599788715204699,55.4257921000452]
["GO:0065005~protein-lipid complex assembly",3,0.630252100840336,0.0466832798785224,"SOAT1, APOE, APOC1",398,12,13528,8.49748743718593,1,0.611762313038574,56.8980912335183]
["GO:0042573~retinoic acid metabolic process",3,0.630252100840336,0.0466832798785224,"RBP1, CRABP2, DHRS9",398,12,13528,8.49748743718593,1,0.611762313038574,56.8980912335183]
["GO:0042354~L-fucose metabolic process",3,0.630252100840336,0.0466832798785224,"GMDS, FUT6, FUT3",398,12,13528,8.49748743718593,1,0.611762313038574,56.8980912335183]
["GO:0007143~female meiosis",3,0.630252100840336,0.0466832798785224,"EREG, TRIP13, CDC25B",398,12,13528,8.49748743718593,1,0.611762313038574,56.8980912335183]
["GO:0031577~spindle checkpoint",3,0.630252100840336,0.0466832798785224,"MAD2L1, TTK, BIRC5",398,12,13528,8.49748743718593,1,0.611762313038574,56.8980912335183]
["GO:0034377~plasma lipoprotein particle assembly",3,0.630252100840336,0.0466832798785224,"SOAT1, APOE, APOC1",398,12,13528,8.49748743718593,1,0.611762313038574,56.8980912335183]
["GO:0009986~cell surface",17,3.57142857142857,0.0473040822923076,"PTPRK, TNFRSF12A, CRYAB, CXCR2, GREM1, ADA, THY1, ALCAM, ANXA9, BGN, ITGA6, APOE, ITGAV, SULF1, CD24, HSPD1, SCNN1B",372,348,12782,1.67851625262637,0.999999980172161,0.344456079073836,48.6843039162331]
["GO:0012505~endomembrane system",32,6.72268907563025,0.0477355289921805,"TM7SF2, GALNT2, CYP3A5, TUSC3, LMNB1, CYP2C18, CBX3, SPINK5, MALL, CHST12, FMO2, ERO1L, SOAT1, LAPTM4B, SLC33A1, PGAP1, CHST2, DHRS9, CYP4F12, NUP155, CYP4B1, TMEM38B, SH3BP4, MAD2L1, ATP2C1, CSGALNACT2, NUCB2, PCNA, NUP107, HSPD1, PARP1, RAB11FIP1",372,782,12782,1.4060446057806,0.999999983201338,0.340533962177553,49.0033311413645]
["GO:0008156~negative regulation of DNA replication",4,0.840336134453781,0.0477870709810322,"CDC6, CDC45, GMNN, POT1",398,28,13528,4.85570710696338,1,0.617609283453785,57.7682180065226]
["GO:0051082~unfolded protein binding",8,1.68067226890756,0.0478487991782877,"PFDN2, CRYAB, HSPE1, CCT2, CCT6A, HSPD1, DNAJC2, SERPINH1",374,115,12983,2.41488026040455,0.999999999999978,0.603797094753587,51.850551507587]
["GO:0019899~enzyme binding",23,4.83193277310924,0.0479152340650311,"PTPRK, KAT2B, NCF2, LYN, NEK2, CBX3, AURKA, CAD, BIRC5, COTL1, GCLM, IRS1, ECT2, POT1, THY1, PPP1R3C, RANBP9, SERPINE1, CD24, LAMB1, TOP2A, FGD6, CBS",374,523,12983,1.52661526978251,0.999999999999979,0.593697145134064,51.9006045901082]
["GO:0005539~glycosaminoglycan binding",9,1.890756302521,0.0488934146137758,"BGN, APOE, ZNF146, LAMC2, VCAN, POSTN, CXCL6, GPNMB, COL5A1",374,140,12983,2.23160809778456,0.999999999999989,0.590971221485812,52.6319847296061]
["GO:0051248~negative regulation of protein metabolic process",11,2.31092436974789,0.0492421217750422,"MAD2L1, ITGAV, BUB1B, DNMT1, CDC20, IGF2BP2, UBE2C, IGFBP3, PAIP2B, PSMB9, TIMP1",398,187,13528,1.99940880874963,1,0.625987744222371,58.8899491064354]
["GO:0001883~purine nucleoside binding",58,12.1848739495798,0.0495077244658334,"TTK, AURKA, CCT2, CAD, AURKB, HSPH1, KIF2C, MCM7, CHST12, DDX60, STK39, TOP2A, CDC7, KIF14, CDK1, CDC6, KIF11, LYN, TPX2, CCT6A, MCM2, PBK, UBE2C, HLTF, CDK4, MCM4, TTF2, MCM5, MCM6, RFC4, RFC2, ATP2C1, BUB1B, RUVBL1, MELK, ACVR1, ABCA8, KIF4A, NEK2, PRKDC, ADA, VRK1, FMO2, PTK6, TGM3, ACTL6A, HSPE1, ERO1L, EHD3, HELLS, TRIP13, KIF18B, ATAD2, RAD54L, DNA2, RAD54B, HSPD1, KIF20A",374,1601,12983,1.25759301506077,0.999999999999993,0.585639576434836,53.0859828730126]
["GO:0030246~carbohydrate binding",17,3.57142857142857,0.0495866114738257,"GALNT2, GALNT6, LGALS1, ENDOU, POSTN, CXCL6, COL5A1, AIM1, BGN, APOE, UPK1A, ZNF146, LAMC2, VCAN, CD24, GPNMB, GALNT12",374,354,12983,1.66705187467899,0.999999999999993,0.576514767419147,53.1439883262843]
["GO:0005789~endoplasmic reticulum membrane",14,2.94117647058823,0.050348912861358,"SOAT1, TM7SF2, CYP3A5, TUSC3, CYP2C18, SLC33A1, PGAP1, DHRS9, CYP4F12, SPINK5, TMEM38B, CYP4B1, FMO2, ERO1L",372,269,12782,1.78826398049326,0.999999993856023,0.34931041878865,50.8967811999673]
["GO:0009890~negative regulation of biosynthetic process",25,5.25210084033613,0.051143449216187,"TBL1XR1, PTPRK, CDC6, GMNN, FST, APOC1, HAT1, CBX3, IGF2BP2, SNAI2, POT1, PAIP2B, CITED2, INHBB, CDC45, HEY1, EREG, APOE, ITGAV, HOPX, TGIF1, DNMT1, ID4, HELLS, KLF4",398,573,13528,1.48298210073052,1,0.637381300689126,60.3134108207325]
["GO:0006790~sulfur metabolic process",8,1.68067226890756,0.052558664707976,"BGN, CHST12, SULF1, GPX3, CSGALNACT2, CHST2, GCLM, CBS",398,115,13528,2.36451824339086,1,0.644807186605037,61.3426173225147]
["GO:0006979~response to oxidative stress",10,2.10084033613445,0.0527114810313182,"PTPRK, PXDN, NUDT1, APOE, CRYAB, GPX3, SERPINE1, COL1A1, GCLM, ADA",398,164,13528,2.07255791150876,1,0.643042692483617,61.452233398739]
["GO:0007076~mitotic chromosome condensation",3,0.630252100840336,0.0541235945705074,"NCAPG, NUSAP1, NCAPD2",398,13,13528,7.84383455740239,1,0.650193655722995,62.4513730436676]
["GO:0005584~collagen type I",2,0.42016806722689,0.0572101266481371,"COL1A2, COL1A1",372,2,12782,34.3602150537634,0.999999999567628,0.380690236206002,55.5621110669075]
["GO:0005607~laminin-2 complex",2,0.42016806722689,0.0572101266481371,"LAMC2, LAMB1",372,2,12782,34.3602150537634,0.999999999567628,0.380690236206002,55.5621110669075]
["GO:0002840~regulation of T cell mediated immune response to tumor cell",2,0.42016806722689,0.0578339673909117,"HSPD1, CD24",398,2,13528,33.9899497487437,1,0.672407516403572,64.9615161838623]
["GO:0045229~external encapsulating structure organization",2,0.42016806722689,0.0578339673909117,"TGM1, TGM3",398,2,13528,33.9899497487437,1,0.672407516403572,64.9615161838623]
["GO:0009217~purine deoxyribonucleoside triphosphate catabolic process",2,0.42016806722689,0.0578339673909117,"NUDT1, ADA",398,2,13528,33.9899497487437,1,0.672407516403572,64.9615161838623]
["GO:0002842~positive regulation of T cell mediated immune response to tumor cell",2,0.42016806722689,0.0578339673909117,"HSPD1, CD24",398,2,13528,33.9899497487437,1,0.672407516403572,64.9615161838623]
["GO:0043163~cell envelope organization",2,0.42016806722689,0.0578339673909117,"TGM1, TGM3",398,2,13528,33.9899497487437,1,0.672407516403572,64.9615161838623]
["GO:0060346~bone trabecula formation",2,0.42016806722689,0.0578339673909117,"COL1A1, MMP2",398,2,13528,33.9899497487437,1,0.672407516403572,64.9615161838623]
["GO:0009204~deoxyribonucleoside triphosphate catabolic process",2,0.42016806722689,0.0578339673909117,"NUDT1, ADA",398,2,13528,33.9899497487437,1,0.672407516403572,64.9615161838623]
["GO:0043066~negative regulation of apoptosis",17,3.57142857142857,0.0584306378817525,"CDK1, CRYAB, SOX4, BIRC5, GCLM, ADA, CITED2, AMIGO2, RNF7, APOE, SERPINB2, HSPD1, HELLS, IFI6, F2R, ALOX12, ACVR1",398,354,13528,1.63228572239729,1,0.67349425293016,65.3500926027619]
["GO:0016814~hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines",4,0.840336134453781,0.0584480771571159,"APOBEC3B, MTHFD2, CDA, ADA",374,31,12983,4.47921338623425,1,0.628946509999719,59.2503539959555]
["GO:0008376~acetylgalactosaminyltransferase activity",4,0.840336134453781,0.0584480771571159,"GALNT2, GALNT6, CSGALNACT2, GALNT12",374,31,12983,4.47921338623425,1,0.628946509999719,59.2503539959555]
["GO:0042803~protein homodimerization activity",16,3.36134453781512,0.0587133621917654,"LGALS1, BIRC5, HPRT1, INHBB, GPD1L, ANXA9, MAD2L1, APOE, FAP, UPK1A, CDA, GYS2, TOP2A, HPGD, CBS, ACVR1",374,334,12983,1.66294149668577,1,0.621351367417223,59.4211594101704]
["GO:0015837~amine transport",8,1.68067226890756,0.0588102718454899,"SLC25A32, RHCG, LYN, PDPN, SLC6A8, SLC38A6, SLC7A11, SLC7A7",398,118,13528,2.30440337279618,1,0.673175759157256,65.595206291379]
["GO:0020037~heme binding",8,1.68067226890756,0.0598087237361653,"CYP3A5, CYP24A1, PXDN, CYP2J2, CYP2C18, CYP4F12, CBS, CYP4B1",374,121,12983,2.29513413178945,1,0.61928046883504,60.1193670712208]
["GO:0001558~regulation of cell growth",11,2.31092436974789,0.0603235341623623,"TMEM97, TNFRSF12A, APOE, CRYAB, FOXM1, CDA, GREM1, DNAJC2, IGFBP3, ALOX12, SPP1",398,194,13528,1.92726519193907,1,0.680006741039354,66.5560985615959]
["GO:0046112~nucleobase biosynthetic process",3,0.630252100840336,0.0619483576329428,"CAD, HPRT1, ADA",398,14,13528,7.28356066044508,1,0.687288394021524,67.5596222353053]
["GO:0006952~defense response",26,5.46218487394958,0.0619817339177725,"CXCL1, CXCL9, RSAD2, CXCR2, CXCL6, CXCL11, CXCL10, MGLL, CD24, BLNK, SPP1, CRISP3, C5AR1, LYN, NCF2, LY96, PDPN, IL1RN, CHST2, COTL1, CCL18, INHBB, APOL1, TFRC, F2R, ACVR1",398,615,13528,1.43697348531274,1,0.684806431776689,67.5799352646554]
["GO:0051351~positive regulation of ligase activity",6,1.26050420168067,0.0630323503545497,"CCNB1, CDK1, CDC20, UBE2C, GCLM, PSMB9",398,73,13528,2.79369449989674,1,0.688455984585611,68.2132492803184]
["GO:0016337~cell-cell adhesion",14,2.94117647058823,0.0639829692138965,"AMIGO2, ANXA9, GMDS, DSG2, PDPN, ATP2C1, FAT1, CRNN, MSN, CD24, CDH3, COL11A1, CEACAM1, THY1",398,276,13528,1.72412788580584,1,0.691432503563053,68.7762120849592]
["GO:0016477~cell migration",14,2.94117647058823,0.0639829692138965,"PTPRK, TNFRSF12A, PRKDC, CXCR2, COL5A1, ITGA6, PRSS3, VCAN, CD24, MSN, SCNN1B, CEACAM1, PLAU, ACVR1",398,276,13528,1.72412788580584,1,0.691432503563053,68.7762120849592]
["GO:0043069~negative regulation of programmed cell death",17,3.57142857142857,0.064124126995431,"CDK1, CRYAB, SOX4, BIRC5, GCLM, ADA, CITED2, AMIGO2, RNF7, APOE, SERPINB2, HSPD1, HELLS, IFI6, F2R, ALOX12, ACVR1",398,359,13528,1.60955193796279,1,0.689638713271341,68.8590003624804]
["GO:0005657~replication fork",4,0.840336134453781,0.0647355891317857,"RPA1, RFC4, RFC2, PCNA",372,32,12782,4.29502688172043,0.999999999976986,0.412863620109391,60.2043953547079]
["GO:0060548~negative regulation of cell death",17,3.57142857142857,0.0660158119969505,"CDK1, CRYAB, SOX4, BIRC5, GCLM, ADA, CITED2, AMIGO2, RNF7, APOE, SERPINB2, HSPD1, HELLS, IFI6, F2R, ALOX12, ACVR1",398,360,13528,1.60508096035734,1,0.697939299489883,69.9486747247989]
["GO:0008285~negative regulation of cell proliferation",17,3.57142857142857,0.0670612034340239,"CXCL1, PTPRK, CDC6, KAT2B, CDKN3, PTHLH, EREG, APOE, SCIN, TGIF1, CD24, KRT4, GPNMB, IGFBP3, PRKRIR, KLF4, F2R",398,361,13528,1.60063475271092,1,0.701244031405543,70.5353233964041]
["GO:0051272~positive regulation of cell motion",7,1.47058823529411,0.068296132485196,"LYN, PDPN, MMP9, LAMB1, IRS1, F2R, CXCL10",398,98,13528,2.42785355348169,1,0.705510267756128,71.2144182829429]
["GO:0051303~establishment of chromosome localization",3,0.630252100840336,0.0701287229112421,"DLGAP5, RRS1, BIRC5",398,15,13528,6.79798994974874,1,0.712849673146836,72.1950170977989]
["GO:0050000~chromosome localization",3,0.630252100840336,0.0701287229112421,"DLGAP5, RRS1, BIRC5",398,15,13528,6.79798994974874,1,0.712849673146836,72.1950170977989]
["GO:0005524~ATP binding",53,11.1344537815126,0.070215200987722,"TTK, AURKA, CCT2, CAD, AURKB, KIF2C, HSPH1, MCM7, DDX60, STK39, TOP2A, CDC7, KIF14, CDK1, CDC6, KIF11, LYN, TPX2, MCM2, PBK, CCT6A, UBE2C, HLTF, CDK4, MCM4, MCM5, TTF2, MCM6, RFC4, RFC2, ATP2C1, BUB1B, RUVBL1, MELK, ACVR1, ABCA8, KIF4A, NEK2, PRKDC, VRK1, PTK6, ACTL6A, HSPE1, EHD3, HELLS, TRIP13, KIF18B, ATAD2, RAD54L, DNA2, RAD54B, HSPD1, KIF20A",374,1477,12983,1.24565802193346,1,0.671373155491253,66.2160843445248]
["GO:0003777~microtubule motor activity",6,1.26050420168067,0.0703869320396973,"KIF14, KIF2C, KIF4A, KIF11, KIF18B, KIF20A",374,77,12983,2.70497951246614,1,0.663686132542645,66.3089764147183]
["GO:0009314~response to radiation",11,2.31092436974789,0.0708964440218958,"PTPRK, SPRR2C, COL3A1, PRKDC, TOPBP1, RAD54B, SERPINB13, SNAI2, RAD54L, IVL, NMU",398,200,13528,1.8694472361809,1,0.714399201771075,72.596377891927]
["GO:0051259~protein oligomerization",10,2.10084033613445,0.0709748592065561,"CRYAB, UPK1A, RRM2, GPX3, CDA, TGM3, ADSL, FADD, HPRT1, IRS1",398,174,13528,1.95344538785883,1,0.712331414302866,72.6370639462931]
["GO:0035108~limb morphogenesis",7,1.47058823529411,0.0710004362000189,"HOXC10, CRABP2, EN1, GREM1, MMP13, PITX1, HOXD11",398,99,13528,2.4033297802142,1,0.710000210232488,72.6503223515494]
["GO:0035107~appendage morphogenesis",7,1.47058823529411,0.0710004362000189,"HOXC10, CRABP2, EN1, GREM1, MMP13, PITX1, HOXD11",398,99,13528,2.4033297802142,1,0.710000210232488,72.6503223515494]
["GO:0006775~fat-soluble vitamin metabolic process",4,0.840336134453781,0.0715939102076084,"CYP24A1, RBP1, CRABP2, DHRS9",398,33,13528,4.11999390893863,1,0.710651125741584,72.9562667425628]
["GO:0032526~response to retinoic acid",4,0.840336134453781,0.0715939102076084,"TFRC, AQP3, KLF4, MEST",398,33,13528,4.11999390893863,1,0.710651125741584,72.9562667425628]
["GO:0030554~adenyl nucleotide binding",56,11.7647058823529,0.0722724732489004,"TTK, AURKA, CCT2, CAD, AURKB, KIF2C, HSPH1, MCM7, CHST12, DDX60, STK39, TOP2A, CDC7, KIF14, CDK1, CDC6, KIF11, LYN, TPX2, CCT6A, MCM2, PBK, UBE2C, HLTF, CDK4, MCM4, TTF2, MCM5, MCM6, RFC4, RFC2, ATP2C1, BUB1B, RUVBL1, MELK, ACVR1, ABCA8, KIF4A, NEK2, PRKDC, VRK1, FMO2, PTK6, ACTL6A, HSPE1, ERO1L, EHD3, HELLS, TRIP13, KIF18B, ATAD2, RAD54L, DNA2, RAD54B, HSPD1, KIF20A",374,1577,12983,1.23270679113866,1,0.665316237385466,67.3133457510436]
["GO:0042113~B cell activation",6,1.26050420168067,0.0723342964056276,"BST2, PRKDC, HSPD1, CD24, ADA, BLNK",398,76,13528,2.68341708542713,1,0.712050830746798,73.3334217919186]
["GO:0050865~regulation of cell activation",10,2.10084033613445,0.0729931848961881,"HMGB3, PDPN, APOE, IL18, HSPD1, RORA, CD24, SPINK5, ADA, THY1",398,175,13528,1.94228284278535,1,0.71301286095551,73.66488445609]
["GO:0000079~regulation of cyclin-dependent protein kinase activity",5,1.05042016806722,0.0734490856441837,"CCNE2, CKS1B, CDC6, CKS2, CDKN3",398,54,13528,3.14721756932812,1,0.712934125766932,73.8919525881416]
["GO:0032868~response to insulin stimulus",7,1.47058823529411,0.0737656588707551,"KAT2B, LYN, GGH, PRKDC, PARP1, LPIN1, IRS1",398,100,13528,2.37929648241206,1,0.712154672515483,74.0485388594885]
["GO:0031396~regulation of protein ubiquitination",7,1.47058823529411,0.0737656588707551,"CCNB1, CDK1, MAD2L1, BUB1B, CDC20, UBE2C, PSMB9",398,100,13528,2.37929648241206,1,0.712154672515483,74.0485388594885]
["GO:0048585~negative regulation of response to stimulus",7,1.47058823529411,0.0737656588707551,"APOE, COL3A1, GREM1, SPINK5, IRS1, ADA, SPP1",398,100,13528,2.37929648241206,1,0.712154672515483,74.0485388594885]
["GO:0008201~heparin binding",7,1.47058823529411,0.0761385685983754,"APOE, ZNF146, LAMC2, POSTN, CXCL6, GPNMB, COL5A1",374,103,12983,2.35919734177872,1,0.676909486347296,69.2859607492905]
["GO:0021700~developmental maturation",7,1.47058823529411,0.0765916632880667,"CCNB1, EREG, SPINK5, MMP2, TRIP13, CDC25B, TIMP1",398,101,13528,2.35573909149708,1,0.723756629255629,75.4076483894998]
["GO:0006289~nucleotide-excision repair",5,1.05042016806722,0.0774665781009503,"RPA1, RFC4, POLE2, RFC2, PCNA",398,55,13528,3.08999543170397,1,0.725627555968315,75.814620968609]
["GO:0046906~tetrapyrrole binding",8,1.68067226890756,0.0783806812337963,"CYP3A5, CYP24A1, PXDN, CYP2J2, CYP2C18, CYP4F12, CBS, CYP4B1",374,129,12983,2.15280023214359,1,0.679916554994257,70.3784918665871]
["GO:0001829~trophectodermal cell differentiation",3,0.630252100840336,0.0786371987488449,"HOPX, ADA, CITED2",398,16,13528,6.37311557788944,1,0.728855696839973,76.3492146968978]
["GO:0033280~response to vitamin D",3,0.630252100840336,0.0786371987488449,"CYP24A1, AQP3, SPP1",398,16,13528,6.37311557788944,1,0.728855696839973,76.3492146968978]
["GO:0007405~neuroblast proliferation",3,0.630252100840336,0.0786371987488449,"ID4, RACGAP1, ASPM",398,16,13528,6.37311557788944,1,0.728855696839973,76.3492146968978]
["GO:0060350~endochondral bone morphogenesis",3,0.630252100840336,0.0786371987488449,"PTHLH, COL1A1, HOXD11",398,16,13528,6.37311557788944,1,0.728855696839973,76.3492146968978]
["GO:0030282~bone mineralization",3,0.630252100840336,0.0786371987488449,"MINPP1, GPNMB, MMP13",398,16,13528,6.37311557788944,1,0.728855696839973,76.3492146968978]
["GO:0010033~response to organic substance",29,6.09243697478991,0.0795872848714128,"PANX1, COL3A1, PRKDC, AURKA, MMP3, HPRT1, SERPINH1, HSPH1, APOE, GYS2, HSPE1, CD24, LOX, ERO1L, SPP1, KAT2B, LYN, CRYAB, LY96, IL1RN, GGH, MMP13, IRS1, LPIN1, TFRC, HSPD1, COL1A1, PARP1, F2R",398,721,13528,1.36714083594114,1,0.730993123996394,76.7748815779051]
["GO:0060284~regulation of cell development",11,2.31092436974789,0.0805645513858874,"LYN, TNFRSF12A, APOE, TGIF1, ID4, CD24, IGFBP3, ASPM, SPP1, HOXD11, THY1",398,205,13528,1.82385096212771,1,0.733215185769793,77.2051805159338]
["GO:0010035~response to inorganic substance",11,2.31092436974789,0.0805645513858874,"PTPRK, PXDN, TFRC, APOE, CRYAB, GPX3, SERPINE1, GGH, COL1A1, AQP3, ADA",398,205,13528,1.82385096212771,1,0.733215185769793,77.2051805159338]
["GO:0006338~chromatin remodeling",5,1.05042016806722,0.0815919000723696,"KAT2B, HJURP, CBX3, ACTL6A, HELLS",398,56,13528,3.03481694185211,1,0.735621043071054,77.6494174990713]
["GO:0042542~response to hydrogen peroxide",5,1.05042016806722,0.0815919000723696,"PXDN, CRYAB, GPX3, COL1A1, ADA",398,56,13528,3.03481694185211,1,0.735621043071054,77.6494174990713]
["GO:0019838~growth factor binding",7,1.47058823529411,0.0818268778304069,"COL4A1, COL3A1, COL1A2, COL1A1, IGFBP3, COL5A1, ACVR1",374,105,12983,2.31426024955436,1,0.688422938363635,71.9872815455847]
["GO:0060173~limb development",7,1.47058823529411,0.0824252818206442,"HOXC10, CRABP2, EN1, GREM1, MMP13, PITX1, HOXD11",398,103,13528,2.30999658486607,1,0.737118471351167,78.0037691046421]
["GO:0048736~appendage development",7,1.47058823529411,0.0824252818206442,"HOXC10, CRABP2, EN1, GREM1, MMP13, PITX1, HOXD11",398,103,13528,2.30999658486607,1,0.737118471351167,78.0037691046421]
["GO:0006916~anti-apoptosis",11,2.31092436974789,0.082673147655355,"CDK1, AMIGO2, RNF7, APOE, CRYAB, SERPINB2, BIRC5, HELLS, IFI6, ALOX12, CITED2",398,206,13528,1.81499731668049,1,0.736003314469579,78.1081342912623]
["GO:0005788~endoplasmic reticulum lumen",6,1.26050420168067,0.0827664197392247,"MINPP1, CES2, P4HA1, SERPINH1, RCN1, CALU",372,80,12782,2.57701612903225,0.999999999999981,0.489703536625384,69.5605343840181]
["GO:0010558~negative regulation of macromolecule biosynthetic process",23,4.83193277310924,0.0835807340426997,"CDC6, TBL1XR1, PTPRK, GMNN, FST, CBX3, HAT1, IGF2BP2, SNAI2, POT1, PAIP2B, CITED2, INHBB, CDC45, EREG, HEY1, ITGAV, HOPX, TGIF1, DNMT1, ID4, KLF4, HELLS",398,547,13528,1.42919349949013,1,0.737807684790304,78.48630596939]
["GO:0017060~3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity",2,0.42016806722689,0.0837433922888277,"FUT6, FUT3",374,3,12983,23.1426024955436,1,0.68955907048517,72.8463161227102]
["GO:0032559~adenyl ribonucleotide binding",53,11.1344537815126,0.0839633017068661,"TTK, AURKA, CCT2, CAD, AURKB, KIF2C, HSPH1, MCM7, DDX60, STK39, TOP2A, CDC7, KIF14, CDK1, CDC6, KIF11, LYN, TPX2, MCM2, PBK, CCT6A, UBE2C, HLTF, CDK4, MCM4, MCM5, TTF2, MCM6, RFC4, RFC2, ATP2C1, BUB1B, RUVBL1, MELK, ACVR1, ABCA8, KIF4A, NEK2, PRKDC, VRK1, PTK6, ACTL6A, HSPE1, EHD3, HELLS, TRIP13, KIF18B, ATAD2, RAD54L, DNA2, RAD54B, HSPD1, KIF20A",374,1497,12983,1.22901596419219,1,0.683057190016592,72.943298043673]
["GO:0016538~cyclin-dependent protein kinase regulator activity",3,0.630252100840336,0.0843121793548677,"CCNE2, CKS1B, CKS2",374,17,12983,6.12598301352626,1,0.677271662314787,73.0964933137043]
["GO:0005588~collagen type V",2,0.42016806722689,0.0845790658505261,"COL5A2, COL5A1",372,3,12782,22.9068100358422,0.999999999999991,0.490248041034613,70.3783565735515]
["GO:0010216~maintenance of DNA methylation",2,0.42016806722689,0.0854873693526034,"DNMT1, HELLS",398,3,13528,22.6599664991624,1,0.743879483000623,79.2607845314137]
["GO:0034447~very-low-density lipoprotein particle clearance",2,0.42016806722689,0.0854873693526034,"APOE, APOC1",398,3,13528,22.6599664991624,1,0.743879483000623,79.2607845314137]
["GO:0033632~regulation of cell-cell adhesion mediated by integrin",2,0.42016806722689,0.0854873693526034,"CD24, ADA",398,3,13528,22.6599664991624,1,0.743879483000623,79.2607845314137]
["GO:0046100~hypoxanthine metabolic process",2,0.42016806722689,0.0854873693526034,"HPRT1, ADA",398,3,13528,22.6599664991624,1,0.743879483000623,79.2607845314137]
["GO:0031055~chromatin remodeling at centromere",2,0.42016806722689,0.0854873693526034,"HJURP, HELLS",398,3,13528,22.6599664991624,1,0.743879483000623,79.2607845314137]
["GO:0001673~male germ cell nucleus",3,0.630252100840336,0.085805444507101,"RPA1, TOPBP1, TRIP13",372,17,12782,6.06356736242884,0.999999999999994,0.488338872149248,70.9200606755758]
["GO:0005605~basal lamina",3,0.630252100840336,0.085805444507101,"LAMA3, LAMC2, LAMB1",372,17,12782,6.06356736242884,0.999999999999994,0.488338872149248,70.9200606755758]
["GO:0045787~positive regulation of cell cycle",5,1.05042016806722,0.0858235767038275,"EREG, DLGAP5, NUSAP1, BIRC5, CITED2",398,57,13528,2.98157453936348,1,0.74315156841339,79.3945951762413]
["GO:0005829~cytosol",48,10.0840336134453,0.090285749827648,"BID, NCBP2, STIL, NEK2, SULT2B1, ADH1B, CAD, CCT2, HPRT1, CALB1, SPINK5, GCLM, ADA, CCNE2, ANXA9, RPL39L, GYS2, CDA, CDCA3, ODC1, CDK1, CDC6, LYN, PPAP2C, GGH, CDC20, BIRC5, FADD, CCT6A, UBE2C, CDK4, ECT2, PSMB9, THY1, CDC25B, CCNB1, PFDN2, MAD2L1, CCNB2, RRM2, NUCB2, BUB1B, ADSL, HSPD1, HPGD, ALOX12, SNRPG, CBS",372,1330,12782,1.24006791171477,0.999999999999999,0.499752895551731,72.821944158085]
["GO:0040007~growth",10,2.10084033613445,0.0904100492703773,"INHBB, CCNB1, GINS1, CCNB2, EREG, SERPINE1, SPINK5, EMP1, PLAU, HOXD11",398,183,13528,1.85737430321003,1,0.759888767186045,81.1405894708693]
["GO:0016324~apical plasma membrane",8,1.68067226890756,0.0924891916418816,"EPCAM, RHCG, CLCA4, PDPN, STK39, MAL, MSN, SCNN1B",372,133,12782,2.06677985285795,0.999999999999999,0.501661172072538,73.7143686294979]
["GO:0004653~polypeptide N-acetylgalactosaminyltransferase activity",3,0.630252100840336,0.0931100344394107,"GALNT2, GALNT6, GALNT12",374,18,12983,5.78565062388591,1,0.707795247712971,76.702432751825]
["GO:0048514~blood vessel morphogenesis",11,2.31092436974789,0.0931322176017925,"BGN, EREG, HEY1, TNFRSF12A, APOE, IL18, CEACAM1, PLAU, CITED2, THY1, ACVR1",398,211,13528,1.77198790159327,1,0.768413697369722,82.1098646117576]
["GO:0045987~positive regulation of smooth muscle contraction",3,0.630252100840336,0.0965349640188182,"ADA, NMU, F2R",398,18,13528,5.66499162479061,1,0.779056345233175,83.2554572150063]
["GO:0050654~chondroitin sulfate proteoglycan metabolic process",3,0.630252100840336,0.0965349640188182,"BGN, CHST12, CSGALNACT2",398,18,13528,5.66499162479061,1,0.779056345233175,83.2554572150063]
["GO:0006004~fucose metabolic process",3,0.630252100840336,0.0965349640188182,"GMDS, FUT6, FUT3",398,18,13528,5.66499162479061,1,0.779056345233175,83.2554572150063]
["GO:0045664~regulation of neuron differentiation",8,1.68067226890756,0.0966852124380032,"TNFRSF12A, APOE, TGIF1, ID4, CD24, ASPM, SPP1, THY1",398,133,13528,2.04450825556353,1,0.77758511138434,83.3044100885012]
["GO:0009266~response to temperature stimulus",6,1.26050420168067,0.096772257888343,"LYN, CRYAB, HSPB8, IL18, ERO1L, CRNN",398,83,13528,2.457104801114,1,0.775891638091798,83.3327088323079]
["GO:0045785~positive regulation of cell adhesion",5,1.05042016806722,0.0991405299934345,"ITGA6, CD24, ALOX12, CITED2, SPP1",398,60,13528,2.83249581239531,1,0.782394921466349,84.0855055758362]
["GO:0007179~transforming growth factor beta receptor signaling pathway",5,1.05042016806722,0.0991405299934345,"PTPRK, COL3A1, COL1A2, HPGD, ACVR1",398,60,13528,2.83249581239531,1,0.782394921466349,84.0855055758362]
["GO:0042330~taxis",9,1.890756302521,0.0991560657172046,"CXCL1, C5AR1, CXCL9, CXCR2, CXCL6, CXCL11, PLAU, CCL18, CXCL10",398,160,13528,1.91193467336683,1,0.780477323191253,84.090336285538]
["GO:0006935~chemotaxis",9,1.890756302521,0.0991560657172046,"CXCL1, C5AR1, CXCL9, CXCR2, CXCL6, CXCL11, PLAU, CCL18, CXCL10",398,160,13528,1.91193467336683,1,0.780477323191253,84.090336285538]
["GO:0055092~sterol homeostasis",4,0.840336134453781,0.0996722368180414,"SOAT1, MALL, APOE, CD24",398,38,13528,3.57788944723618,1,0.780335506137944,84.2500515105853]
["GO:0042632~cholesterol homeostasis",4,0.840336134453781,0.0996722368180414,"SOAT1, MALL, APOE, CD24",398,38,13528,3.57788944723618,1,0.780335506137944,84.2500515105853]
["GO:0048477~oogenesis",4,0.840336134453781,0.0996722368180414,"CCNB1, EREG, TRIP13, CDC25B",398,38,13528,3.57788944723618,1,0.780335506137944,84.2500515105853]
[]
[]
["supplementary material 2"]
["Category","Term","Count","%","PValue","Genes","List Total","Pop Hits","Pop Total","Fold Enrichment","Bonferroni","Benjamini","FDR"]
["KEGG_PATHWAY","hsa04110:Cell cycle",22,6.6066066066066,2.79249797120986e-12,"CDC7, CDK1, CDC6, E2F3, DBF4, PRKDC, TTK, CDC20, MCM2, CDK4, MCM4, MCM5, MCM6, CDC25B, CCNE2, CCNB1, CDC45, CCNB2, MCM7, MAD2L1, PCNA, BUB1B",131,125,5085,6.83175572519083,2.90424573279324e-10,2.90424573279324e-10,3.12241343891628e-09]
["KEGG_PATHWAY","hsa04512:ECM-receptor interaction",17,5.1051051051051,1.93226625195216e-10,"COL4A2, COL4A1, TNC, COL3A1, COL5A2, COL5A1, LAMB3, LAMA3, ITGA6, ITGAV, COL6A3, COL1A2, LAMC2, COL1A1, LAMB1, COL11A1, SPP1",131,84,5085,7.85577971646673,2.00955720952578e-08,1.00477861586512e-08,2.16051931900551e-07]
["KEGG_PATHWAY","hsa03030:DNA replication",12,3.6036036036036,6.9611952600188e-10,"RPA1, DNA2, MCM7, RFC4, POLE2, RFC2, PCNA, MCM2, RNASEH2A, MCM4, MCM5, MCM6",131,36,5085,12.9389312977099,7.23964249660369e-08,2.41321421734497e-08,7.78349973362679e-07]
["KEGG_PATHWAY","hsa05222:Small cell lung cancer",12,3.6036036036036,7.57740089984362e-06,"CCNE2, CKS1B, E2F3, LAMB3, COL4A2, LAMA3, COL4A1, ITGA6, ITGAV, LAMC2, LAMB1, CDK4",131,84,5085,5.54525627044711,0.00078774224732192,0.000196993764000841,0.00847216941715078]
["KEGG_PATHWAY","hsa04510:Focal adhesion",17,5.1051051051051,4.41187823784371e-05,"COL4A2, COL4A1, TNC, COL3A1, COL5A2, COL5A1, LAMB3, LAMA3, ITGA6, ITGAV, COL6A3, COL1A2, LAMC2, COL1A1, LAMB1, COL11A1, SPP1",131,201,5085,3.28301241882192,0.00457794371123809,0.000917269967790179,0.049319322231156]
["KEGG_PATHWAY","hsa04115:p53 signaling pathway",9,2.7027027027027,0.000299482074900512,"CCNE2, CCNB1, BID, CDK1, CCNB2, RRM2, SERPINE1, CDK4, IGFBP3",131,68,5085,5.13751683879658,0.0306706133757499,0.00517834599556965,0.334348938764872]
["KEGG_PATHWAY","hsa05200:Pathways in cancer",19,5.7057057057057,0.00154751455498063,"BID, CKS1B, E2F3, COL4A2, COL4A1, MMP9, FADD, BIRC5, CDK4, MMP2, MMP1, FZD6, CCNE2, LAMB3, LAMA3, ITGA6, ITGAV, LAMC2, LAMB1",131,328,5085,2.24853379258983,0.14876425873576,0.0227467543861941,1.71675094587869]
["KEGG_PATHWAY","hsa03430:Mismatch repair",4,1.2012012012012,0.0198986562352473,"RPA1, RFC4, RFC2, PCNA",131,23,5085,6.75074676402256,0.87635333647154,0.229943129116235,20.1272704917337]
["KEGG_PATHWAY","hsa05219:Bladder cancer",5,1.5015015015015,0.0215615557820012,"E2F3, MMP9, CDK4, MMP2, MMP1",131,42,5085,4.62104689203925,0.896370148968614,0.222662838003216,21.6295021988035]
["KEGG_PATHWAY","hsa03420:Nucleotide excision repair",5,1.5015015015015,0.0251529354882351,"RPA1, RFC4, POLE2, RFC2, PCNA",131,44,5085,4.41099930603747,0.929304010172539,0.232745440513929,24.7864837257327]
["KEGG_PATHWAY","hsa04114:Oocyte meiosis",7,2.1021021021021,0.0615946828546383,"CCNE2, CCNB1, CDK1, MAD2L1, CCNB2, CDC20, AURKA",131,110,5085,2.47015961138098,0.998655354419508,0.451768042164815,50.8763884159799]
["KEGG_PATHWAY","hsa04666:Fc gamma R-mediated phagocytosis",6,1.8018018018018,0.0949747058920106,"ARPC1B, LYN, MARCKSL1, PPAP2C, ASAP1, FCGR2A",131,95,5085,2.45158698272398,0.999968903279165,0.578892590609311,67.23487751568]
[]
[]
["supplementary material 3"]
["MCODE App Results"]
["Date: 2020-3-8 0:37:21"]
[]
["Parameters:"]
["   Network Scoring:"]
["      Include Loops: false  Degree Cutoff: 2"]
["   Cluster Finding:"]
["      Node Score Cutoff: 0.2  Haircut: true  Fluff: false  K-Core: 2  Max. Depth from Seed: 100"]
[]
["Cluster","Score (Density*#Nodes)","Nodes","Edges","Node IDs"]
[1,66.056,73,2378,"PCNA, RFC4, DTL, MELK, CDC7, STIL, MCM2, ASPM, MCM10, DLGAP5, GINS2, NDC80, TROAP, AURKA, MAD2L1, BIRC5, BUB1B, AURKB, CDK1, RRM2, KIF4A, CCNB1, CCNB2, KIF14, TPX2, CEP55, CDC6, CDC45, RAD54L, RAD51AP1, GINS1, MCM7, MCM4, ZWINT, MCM5, MCM6, HELLS, NEK2, CDC20, ATAD2, CDCA3, OIP5, HJURP, CENPM, NUSAP1, CENPN, FANCI, CCNE2, MYBL2, PBK, FOXM1, UBE2C, KIAA0101, KIF2C, NCAPG, NCAPD2, TOP2A, KIF11, KIF18B, KIF20A, PRC1, ECT2, GMNN, RACGAP1, EZH2, CKS2, TTK, POLE2, TRIP13, RNASEH2A, CDCA8, CDKN3, CKS1B"]
[2,21.758,34,359,"IGFBP3, MMP3, MMP1, PCOLCE, COL5A1, COL1A1, COL1A2, PLOD3, SERPINH1, COLGALT1, LOX, COL3A1, LAMB1, LUM, MMP13, COL4A5, POSTN, NID2, SERPINE1, SPP1, P4HA1, COL7A1, COL4A2, COL4A1, VCAN, COL6A3, BGN, COL5A2, MMP2, TIMP1, ITGAV, MMP9, COL10A1, SPARC"]
[3,8.621,30,125,"IFI44L, ACKR3, CXCL1, IFI6, RSAD2, NMU, IL18, RCN1, APOE, TNC, LCN2, USP18, ISG15, BST2, PSMB9, PLAU, MMP10, MMP7, LGALS1, C5AR1, CXCL6, APOL1, IFIT1, CXCL11, IFI44, CALU, CXCL10, CXCL9, DDX60, CXCR2"]
[4,8.5,9,34,"SPRR2B, SPRR3, DSG2, TGM1, IVL, EVPL, FLG, PPL, SCEL"]
[5,4,5,8,"DNA2, RFC2, GINS4, RAD54B, TOPBP1"]
[6,4,4,6,"PSCA, PRSS21, LYPD3, CEACAM7"]
[7,3.429,8,12,"IL1RN, THY1, SNAI2, CCL18, SERPINB2, FCGR2A, CXCL8, MMP12"]
[8,3.333,4,5,"CYP4B1, TMOD3, CYP4F12, CYP2J2"]
[9,3.091,12,17,"ACPP, RBM28, CEACAM6, RRS1, ALCAM, PUS7, TMPRSS2, LSG1, EPCAM, CD24, LPCAT1, TFRC"]
[10,3,3,3,"PARP1, PRKDC, OBFC1"]
[11,3,3,3,"CDA, POLR2H, CTPS1"]
[12,3,3,3,"KRT75, KRT4, KRT24"]
[13,3,3,3,"HSPD1, HSPH1, HSPE1"]
[14,3,3,3,"ACVR1, FST, INHBB"]

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