Lead SNP	CHR	BP	non_effect_allele	effect_allele	MAF	p	beta	se	GenomicLocus	chr	bp	rsID of reported SNP in GWAS catalog	DateAddedToCatalog	PMID	FirstAuth	Date	Journal	Link	Study	Trait	InitialN	ReplicationN	Region	ReportedGene	MappedGene	UpGene	DownGene	SNP_Gene_ID	UpGeneDist	DownGeneDist	Strongest	SNPs	marged	SNP_ID_cur	Context	intergenic	RiskAF	P	Pmlog	Ptext	OrBeta	95CI	Platform	CNV
rs10068046	5	89252602	G	A	0.183897	7.16015446342e-09	-0.00646198636847	0.00111661438354	73	5	89353210	rs166820	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		5q14.3	NR	MIR3660 - LINC01339	ENSG00000264342	ENSG00000248555	""	40673	95659	rs166820-A	rs166820	0	166820	regulatory_region_variant	1	NR	1E-11	11	""	6.761	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs10068046	5	89252602	G	A	0.183897	7.16015446342e-09	-0.00646198636847	0.00111661438354	73	5	89374758	rs554096341	2021-05-06	33888908	Pirastu N	2021-04-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33888908	Genetic analyses identify widespread sex-differential participation bias.	Biological sex	1,301,549 European ancestry cases, 1,160,583 European ancestry controls		5q14.3		MIR3660 - LINC01339	ENSG00000264342	ENSG00000248555	""	62221	74111	rs554096341-T	rs554096341	0	554096341	intergenic_variant	1	""	1E-8	8	""	0.0149632	[0.0098-0.0201] unit increase	Illumina [13288253] (imputed)	N
rs10068046	5	89252602	G	A	0.183897	7.16015446342e-09	-0.00646198636847	0.00111661438354	73	5	89286254	rs1560208	2019-09-04	31374203	Lam M	2019-08-01	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/31374203	Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy)	328,917 individuals with educational attainment measurements, 107,207 individuals with cognitive ability measurements, 77,096 European ancestry schizophrenia cases, 43,456 European ancestry controls		5q14.3	MIR3660	NA - MIR3660	""	ENSG00000264342	""		26184	rs1560208-?	rs1560208	0	1560208	intron_variant	1	NR	1E-8	8	""	0.014982785	[0.0098-0.0202] unit decrease	NR [7306098]	N
rs10068046	5	89252602	G	A	0.183897	7.16015446342e-09	-0.00646198636847	0.00111661438354	73	5	89399330	rs1698135	2020-02-05	31666681	Zhao B	2019-10-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/31666681	Large-scale GWAS reveals genetic architecture of brain white matter microstructure and genetic overlap with cognitive and mental health traits (n = 17,706).	White matter microstructure (fractional anisotropy)	17,706 European ancestry individuals		5q14.3	NR	MIR3660 - LINC01339	ENSG00000264342	ENSG00000248555	""	86793	49539	rs1698135-?	rs1698135	0	1698135	intergenic_variant	1	""	2E-8	7.69897000433602	(Sagittal stratum)		""	NR [8955960] (imputed)	N
rs10068046	5	89252602	G	A	0.183897	7.16015446342e-09	-0.00646198636847	0.00111661438354	73	5	89353210	rs166820	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		5q14.3	MIR3660	MIR3660 - LINC01339	ENSG00000264342	ENSG00000248555	""	40673	95659	rs166820-A	rs166820	0	166820	regulatory_region_variant	1	NR	2E-8	7.69897000433602	""	0.022414079	[0.015-0.03] unit increase	Affymetrix [NR]	N
rs10068046	5	89252602	G	A	0.183897	7.16015446342e-09	-0.00646198636847	0.00111661438354	73	5	89353210	rs166820	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		5q14.3	""	MIR3660 - LINC01339	ENSG00000264342	ENSG00000248555	""	40673	95659	rs166820-?	rs166820	0	166820	regulatory_region_variant	1	NR	1E-10	10	""		""	NR [6307410] (imputed)	N
rs4463453	8	118871476	T	C	0.363817	3.17544231056e-09	-0.00569128541822	0.000960998676128	113	8	118902809	rs7814022	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		8q24.11	EXT1	EXT1	""	""	ENSG00000182197			rs7814022-A	rs7814022	0	7814022	intron_variant	0	NR	9E-9	8.04575749056068	""	5.756	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4463453	8	118871476	T	C	0.363817	3.17544231056e-09	-0.00569128541822	0.000960998676128	113	8	118901928	rs13280053	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		8q24.11	Intergenic	EXT1	""	""	ENSG00000182197			rs13280053-T	rs13280053	0	13280053	intron_variant	0	0.4821	5E-8	7.30102999566398	(MTAG)	0.0098	[0.0063-0.0133] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs4463453	8	118871476	T	C	0.363817	3.17544231056e-09	-0.00569128541822	0.000960998676128	113	8	118907971	rs7841914	2021-12-15	34560273	Shadrin AA	2021-09-21	Neuroimage	www.ncbi.nlm.nih.gov/pubmed/34560273	Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.	Cortical surface area	35,657 White British ancestry individuals		8q24.11	NR	EXT1	""	""	ENSG00000182197			rs7841914-A	rs7841914	0	7841914	intron_variant	0	0.4273	5E-14	13.301029995664	""		""	NR [9056863] (imputed)	N
rs4463453	8	118871476	T	C	0.363817	3.17544231056e-09	-0.00569128541822	0.000960998676128	113	8	118903024	rs9692869	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		8q24.11	Intergenic	EXT1	""	""	ENSG00000182197			rs9692869-T	rs9692869	0	9692869	intron_variant	0	0.5729	5E-11	10.301029995664	(MTAG)	0.0152	[0.011-0.02] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs4463453	8	118871476	T	C	0.363817	3.17544231056e-09	-0.00569128541822	0.000960998676128	113	8	118907971	rs7841914	2022-03-07	34910505	van der Meer D	2021-12-15	Sci Adv	www.ncbi.nlm.nih.gov/pubmed/34910505	The genetic architecture of human cortical folding.	Vertex-wise cortical surface area	33,748 European ancestry individuals		8q24.11	""	EXT1	""	""	ENSG00000182197			rs7841914-A	rs7841914	0	7841914	intron_variant	0	0.42	3E-12	11.5228787452803	""	6.97	z score increase	Affymetrix [9061022] (imputed)	N
rs4463453	8	118871476	T	C	0.363817	3.17544231056e-09	-0.00569128541822	0.000960998676128	113	8	118907971	rs7841914	2022-03-07	34910505	van der Meer D	2021-12-15	Sci Adv	www.ncbi.nlm.nih.gov/pubmed/34910505	The genetic architecture of human cortical folding.	Vertex-wise sulcal depth	33,748 European ancestry individuals		8q24.11	""	EXT1	""	""	ENSG00000182197			rs7841914-A	rs7841914	0	7841914	intron_variant	0	0.42	3E-23	22.5228787452803	""	9.95	z score increase	Affymetrix [9061022] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	132945754	rs10215367	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		7q33	EXOC4	EXOC4	""	""	ENSG00000131558			rs10215367-T	rs10215367	0	10215367	intron_variant	0	NR	2E-10	9.69897000433602	""	0.019046552	[0.013-0.025] unit increase	Affymetrix [NR]	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	132956034	rs10262862	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		7q33	""	EXOC4	""	""	ENSG00000131558			rs10262862-T	rs10262862	0	10262862	intron_variant	0	0.6092	4E-9	8.39794000867204	""	0.00633621	[0.0042-0.0085] unit increase	Illumina [10675380] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133054712	rs6950324	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		7q33	EXOC4	EXOC4	""	""	ENSG00000131558			rs6950324-T	rs6950324	0	6950324	intron_variant	0	NR	2E-8	7.69897000433602	""	5.661	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	132945754	rs10215367	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		7q33	""	EXOC4	""	""	ENSG00000131558			rs10215367-?	rs10215367	0	10215367	intron_variant	0	NR	5E-12	11.301029995664	""		""	NR [6307410] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133055082	rs1149557	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		7q33	NR	EXOC4	""	""	ENSG00000131558			rs1149557-C	rs1149557	0	1149557	intron_variant	0	0.385686	2E-11	10.698970004336	""	0.043276563	[0.031-0.056] unit increase	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133047756	rs1149558	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken	430,445 European ancestry individuals		7q33	Intergenic	EXOC4	""	""	ENSG00000131558			rs1149558-T	rs1149558	0	1149558	intron_variant	0	0.6032	6E-9	8.22184874961636	""	0.0135	[0.009-0.018] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs4291171	7	39269010	G	T	0.351889	5.91744191075e-10	0.00594568028929	0.000960124436717	97	7	39168281	rs112503449	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		7p14.1	Intergenic	POU6F2	""	""	ENSG00000106536			rs112503449-A	rs112503449	0	112503449	intron_variant	0	0.0705	3E-8	7.52287874528034	(MTAG)	0.0194	[0.013-0.026] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs4291171	7	39269010	G	T	0.351889	5.91744191075e-10	0.00594568028929	0.000960124436717	97	7	39246987	rs113205706	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		7p14.1	""	POU6F2	""	""	ENSG00000106536			rs113205706-A	rs113205706	0	113205706	splice_region_variant	0	0.0944	2E-8	7.69897000433602	""	0.0135	[0.0088-0.0182] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs4291171	7	39269010	G	T	0.351889	5.91744191075e-10	0.00594568028929	0.000960124436717	97	7	39168281	rs112503449	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		7p14.1	Intergenic	POU6F2	""	""	ENSG00000106536			rs112503449-A	rs112503449	0	112503449	intron_variant	0	0.0703	1E-12	12	(MTAG)	0.0228	[0.017-0.029] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs4291171	7	39269010	G	T	0.351889	5.91744191075e-10	0.00594568028929	0.000960124436717	97	7	39191427	rs73695675	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		7p14.1	""	POU6F2	""	""	ENSG00000106536			rs73695675-T	rs73695675	0	73695675	intron_variant	0	0.0733	2E-11	10.698970004336	""	0.0134195	[0.0095-0.0174] unit decrease	Illumina [10675380] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39874314	rs2899319	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Reticulocyte count	408,112 British individuals		22q13.1	MGAT3	MGAT3	""	""	ENSG00000128268			rs2899319-C	rs2899319	0	2899319	intron_variant	0	0.617488	8E-12	11.0969100130081	""	0.0158838	[0.011-0.02] unit increase	Affymetrix [93095623] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39874314	rs2899319	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Reticulocyte fraction of red cells	408,112 British individuals		22q13.1	MGAT3	MGAT3	""	""	ENSG00000128268			rs2899319-C	rs2899319	0	2899319	intron_variant	0	0.617498	1E-11	11	""	0.01574192	[0.011-0.02] unit increase	Affymetrix [93095623] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39897163	rs7287617	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Serum alkaline phosphatase levels	344,292 European ancestry individuals, 118,886 East Asian ancestry individuals		22q13.1	""	MIEF1	""	""	ENSG00000100335			rs7287617-A	rs7287617	0	7287617	intron_variant	0	NR	1E-19	19	""	0.0223	[0.018-0.027] unit increase	Affymetrix, Illumina [20533886] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39874314	rs2899319	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	High light scatter reticulocyte count	408,112 British individuals		22q13.1	MGAT3	MGAT3	""	""	ENSG00000128268			rs2899319-C	rs2899319	0	2899319	intron_variant	0	0.617424	3E-14	13.5228787452803	""	0.017592318	[0.013-0.022] unit increase	Affymetrix [93095623] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39874314	rs2899319	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	High light scatter reticulocyte percentage of red cells	408,112 British individuals		22q13.1	MGAT3	MGAT3	""	""	ENSG00000128268			rs2899319-C	rs2899319	0	2899319	intron_variant	0	0.617445	2E-14	13.698970004336	""	0.01765451	[0.013-0.022] unit increase	Affymetrix [93095623] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39897163	rs7287617	2021-06-09	33972514	Pazoki R	2021-05-10	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/33972514	Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes.	Liver enzyme levels (alkaline phosphatase)	437,438 European ancestry individuals	315,572 European ancestry individuals	22q13.1	MIEF1	MIEF1	""	""	ENSG00000100335			rs7287617-G	rs7287617	0	7287617	intron_variant	0	0.352591	2E-28	27.698970004336	""	0.00267079	[0.0022-0.0032] unit decrease	Affymetrix [13995440] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39874314	rs2899319	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		22q13.1	NR	MGAT3	""	""	ENSG00000128268			rs2899319-A	rs2899319	0	2899319	intron_variant	0	NR	1E-8	8	""	5.662	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs1043254	14	69708241	A	G	0.244533	2.56911517068e-09	0.00660641290309	0.00110901692166	165	14	69716957	rs17106817	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		14q24.1	Intergenic	EXD2 - GALNT16	ENSG00000081177	ENSG00000100626	""	6220	9037	rs17106817-T	rs17106817	0	17106817	intron_variant	1	0.7253	8E-12	11.0969100130081	(MTAG)	0.0176	[0.013-0.023] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs1043254	14	69708241	A	G	0.244533	2.56911517068e-09	0.00660641290309	0.00110901692166	165	14	69716957	rs17106817	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		14q24.1	NR	EXD2 - GALNT16	ENSG00000081177	ENSG00000100626	""	6220	9037	rs17106817-T	rs17106817	0	17106817	intron_variant	1	NR	2E-8	7.69897000433602	""	5.591	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs1043254	14	69708241	A	G	0.244533	2.56911517068e-09	0.00660641290309	0.00110901692166	165	14	69702328	rs6573878	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		14q24.1	EXD2	EXD2	""	""	ENSG00000081177			rs6573878-T	rs6573878	0	6573878	intron_variant	0	NR	5E-9	8.30102999566398	""	0.021243362	[0.014-0.028] unit increase	Affymetrix [NR]	N
rs1043254	14	69708241	A	G	0.244533	2.56911517068e-09	0.00660641290309	0.00110901692166	165	14	69708241	rs1043254	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		14q24.1	NR	EXD2	""	""	ENSG00000081177			rs1043254-G	rs1043254	0	1043254	3_prime_UTR_variant	0	0.244533	8E-9	8.09691001300806	""	0.04210653	[0.028-0.056] unit increase	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs1043254	14	69708241	A	G	0.244533	2.56911517068e-09	0.00660641290309	0.00110901692166	165	14	69709373	rs3173	2021-06-29	32895543	de la Fuente J	2020-09-07	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/32895543	A general dimension of genetic sharing across diverse cognitive traits inferred from molecular data.	Verbal-numerical reasoning	171,304 British ancestry individuals		14q24.1	""	EXD2	""	""	ENSG00000081177			rs3173-?	rs3173	0	3173	3_prime_UTR_variant	0	NR	1E-8	8	""		""	NR [7857346] (imputed)	N
rs1043254	14	69708241	A	G	0.244533	2.56911517068e-09	0.00660641290309	0.00110901692166	165	14	69592739	rs1275406	2022-08-16	35627254	Mansachs SJ	2022-05-12	Genes (Basel)	www.ncbi.nlm.nih.gov/pubmed/35627254	Genetic Variants Associated with Neuropeptide Y Autoantibody Levels in Newly Diagnosed Individuals with Type 1 Diabetes.	Neuropeptide Y autoantibody levels in type 1 diabetes	546 European ancestry children		14q24.1	""	DCAF5	""	""	ENSG00000139990			rs1275406-G	rs1275406	0	1275406	intron_variant	0	NR	2E-6	5.69897000433602	""		""	Illumina [3119616] (imputed)	N
rs1043254	14	69708241	A	G	0.244533	2.56911517068e-09	0.00660641290309	0.00110901692166	165	14	69708241	rs1043254	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance	257,841 European ancestry individuals		14q24.1	Intergenic	EXD2	""	""	ENSG00000081177			rs1043254-A	rs1043254	0	1043254	3_prime_UTR_variant	0	0.23	7E-9	8.15490195998574	""	0.0197	[0.013-0.026] unit decrease	Affymetrix, Illumina [10100000] (imputed)	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122663012	rs9775606	2019-08-05	31168069	Ward J	2019-06-05	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/31168069	The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function.	Mood instability	157,039 European ancestry cases, 206,666 European ancestry controls		9q33.2	intergenic	NA - LINC01613	""	ENSG00000261432	""		34319	rs9775606-?	rs9775606	0	9775606	intergenic_variant	1	NR	1E-8	8	""	0.00666083	[0.0044-0.0089] unit decrease	Affymetrix [NR] (imputed)	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122655283	rs60393230	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Depressed affect	357,957 European ancestry individuals		9q33.2	NR	NA - LINC01613	""	ENSG00000261432	""		42048	rs60393230-A	rs60393230	0	60393230	intergenic_variant	1	NR	4E-9	8.39794000867204	""	0.01397	[0.0093-0.0186] unit decrease	Affymetrix [10847151] (imputed)	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122662720	rs9775587	2021-09-30	34045744	Levey DF	2021-05-27	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/34045744	Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions.	Major depressive disorder	340,591 European ancestry cases, 813,676 European ancestry controls	455,350 cases, 887,428 controls	9q33.2	""	NA - LINC01613	""	ENSG00000261432	""		34611	rs9775587-?	rs9775587	0	9775587	intergenic_variant	1	NR	1E-12	12	""	0.0197	unit increase	NR [NR]	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122660054	rs12553064	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		9q33.2	Intergenic	NA - LINC01613	""	ENSG00000261432	""		37277	rs12553064-A	rs12553064	0	12553064	intergenic_variant	1	0.6059	7E-9	8.15490195998574	(MTAG)	0.0078	[0.0053-0.0103] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122657003	rs10818399	2022-08-05	35835914	Watanabe K	2022-07-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35835914	Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.	Insomnia	593,724 European ancestry cases, 1,771,286 European ancestry controls		9q33.2	""	BRINP1 - LINC01613	ENSG00000078725	ENSG00000261432	""	525290	40328	rs10818399-C	rs10818399	0	10818399	intergenic_variant	1	NR	1E-11	11	""	0.006	[0.004-0.008] unit decrease	Illumina [10713943] (imputed)	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122655283	rs60393230	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Neuroticism	449,484 European ancestry individuals		9q33.2	NR	NA - LINC01613	""	ENSG00000261432	""		42048	rs60393230-A	rs60393230	0	60393230	intergenic_variant	1	NR	4E-8	7.39794000867204	""	5.502	z score decrease	Affymetrix [10847151] (imputed)	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122660715	rs952191	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		9q33.2	NR	NA - LINC01613	""	ENSG00000261432	""		36616	rs952191-?	rs952191	0	952191	intergenic_variant	1	NR	1E-6	6	""	4.84	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122674412	rs1333904	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		9q33.2	Intergenic	NA - LINC01613	""	ENSG00000261432	""		22919	rs1333904-T	rs1333904	0	1333904	intergenic_variant	1	0.594	6E-9	8.22184874961636	(MTAG)	0.0136	[0.0091-0.0181] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122663466	rs4836789	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Experiencing mood swings	373,733 European ancestry individuals		9q33.2	NR	NA - LINC01613	""	ENSG00000261432	""		33865	rs4836789-T	rs4836789	0	4836789	intergenic_variant	1	0.402872	1E-8	8	""	5.71	z score decrease	NR [10847151] (imputed)	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122664468	rs10818400	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Life satisfaction	80,852 European ancestry individuals		9q33.2	NR	NA - LINC01613	""	ENSG00000261432	""		32863	rs10818400-G	rs10818400	0	10818400	intergenic_variant	1	0.605687587251465	1E-12	12	""	0.008991932	[0.0065-0.0115] unit increase	NR [NR]	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122676273	rs7873013	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Angina pectoris	30,025 European ancestry cases, 440,906 European ancestry controls, 14,007 East Asian ancestry cases, 145,158 East Asian ancestry controls		9q33.2	""	BRINP1 - LINC01613	ENSG00000078725	ENSG00000261432	""	544560	21058	rs7873013-T	rs7873013	0	7873013	intergenic_variant	1	NR	2E-9	8.69897000433602	""	0.0506	[0.034-0.067] unit increase	Affymetrix, Illumina [25842036] (imputed)	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122674412	rs1333904	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		9q33.2	Intergenic	NA - LINC01613	""	ENSG00000261432	""		22919	rs1333904-T	rs1333904	0	1333904	intergenic_variant	1	0.6087	2E-9	8.69897000433602	(MTAG)	0.0111	[0.0076-0.0146] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122674412	rs1333904	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		9q33.2	Intergenic	NA - LINC01613	""	ENSG00000261432	""		22919	rs1333904-T	rs1333904	0	1333904	intergenic_variant	1	0.6079	2E-10	9.69897000433602	(MTAG)	0.0107	[0.0074-0.014] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122675981	rs12336873	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		9q33.2	""	BRINP1 - LINC01613	ENSG00000078725	ENSG00000261432	""	544268	21350	rs12336873-T	rs12336873	0	12336873	intergenic_variant	1	0.3941	6E-7	6.22184874961636	""	0.00535862	[0.0033-0.0075] unit increase	Illumina [10675380] (imputed)	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122664468	rs10818400	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Neuroticism	523,783 European ancestry individuals	59,206 European ancestry individuals	9q33.2	NR	NA - LINC01613	""	ENSG00000261432	""		32863	rs10818400-G	rs10818400	0	10818400	intergenic_variant	1	0.605687587251465	2E-13	12.698970004336	""	0.011010994	[0.0081-0.014] unit increase	NR [NR]	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122664468	rs10818400	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Positive affect	410,603 European ancestry individuals		9q33.2	NR	NA - LINC01613	""	ENSG00000261432	""		32863	rs10818400-G	rs10818400	0	10818400	intergenic_variant	1	0.605687587251465	1E-12	12	""	0.008432748	[0.0061-0.0108] unit increase	NR [NR]	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122668048	rs1360692	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Well-being spectrum (multivariate analysis)	2,083,151 European ancestry individuals	287,239 European ancestry individuals	9q33.2	NR	NA - LINC01613	""	ENSG00000261432	""		29283	rs1360692-T	rs1360692	0	1360692	intergenic_variant	1	0.604426454049253	3E-13	12.5228787452803	""	0.0068362597	[0.005-0.0087] unit increase	NR [NR]	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122664468	rs10818400	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Depressive symptoms	1,067,913 European ancestry individuals	228,033 European ancestry individuals	9q33.2	NR	NA - LINC01613	""	ENSG00000261432	""		32863	rs10818400-G	rs10818400	0	10818400	intergenic_variant	1	0.605687587251465	2E-13	12.698970004336	""	0.0070496965	[0.0052-0.0089] unit increase	NR [NR]	N
rs10465137	9	122659596	T	C	0.388668	9.96610467789e-09	0.00543960077763	0.000949103398304	124	9	122664468	rs10818400	2020-08-17	31926635	Coleman JRI	2019-11-01	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/31926635	The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls.	Bipolar disorder or major depressive disorder	164,933 European ancestry major depressive disorder cases, 20,352 European ancestry bipolar disorder cases, 439,741 European ancestry controls		9q33.2	NR	NA - LINC01613	""	ENSG00000261432	""		32863	rs10818400-G	rs10818400	0	10818400	intergenic_variant	1	NR	1E-8	8	""	1.0204082	""	NR [NR] (imputed)	N
rs10736180	10	107363588	A	G	0.445328	4.50712623916e-09	0.0055341615499	0.000943684811806	133	10	107363588	rs10736180	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		10q25.1	NR	RNU6-463P - PPIAP38	ENSG00000207068	ENSG00000233477	""	69065	81553	rs10736180-?	rs10736180	0	10736180	intergenic_variant	1	NR	6E-8	7.22184874961636	""	5.42	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs10736180	10	107363588	A	G	0.445328	4.50712623916e-09	0.0055341615499	0.000943684811806	133	10	107340162	rs11192507	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		10q25.1	""	RNU6-463P - PPIAP38	ENSG00000207068	ENSG00000233477	""	45639	104979	rs11192507-A	rs11192507	0	11192507	intergenic_variant	1	0.5887	6E-17	16.2218487496164	""	0.00889855	[0.0068-0.011] unit decrease	Illumina [10675380] (imputed)	N
rs10736180	10	107363588	A	G	0.445328	4.50712623916e-09	0.0055341615499	0.000943684811806	133	10	107340162	rs11192507	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		10q25.1	Intergenic	RNU6-463P - PPIAP38	ENSG00000207068	ENSG00000233477	""	45639	104979	rs11192507-A	rs11192507	0	11192507	intergenic_variant	1	0.5926	4E-8	7.39794000867204	(MTAG)	0.0092	[0.0059-0.0125] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs10763931	10	33677323	G	A	0.261431	4.17269122388e-10	0.00642003440278	0.00102762855422	128	10	33676655	rs7079083	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		10p11.22	NR	NRP1 - NA	ENSG00000099250	""	""	51465		rs7079083-?	rs7079083	0	7079083	intron_variant	1	NR	1E-7	7	""	5.296	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs10763931	10	33677323	G	A	0.261431	4.17269122388e-10	0.00642003440278	0.00102762855422	128	10	33676655	rs7079083	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		10p11.22	Intergenic	NRP1 - NA	ENSG00000099250	""	""	51465		rs7079083-A	rs7079083	0	7079083	intron_variant	1	0.7132	8E-12	11.0969100130081	(MTAG)	0.0135	[0.0096-0.0174] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs10763931	10	33677323	G	A	0.261431	4.17269122388e-10	0.00642003440278	0.00102762855422	128	10	33676655	rs7079083	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability	564,698 European ancestry individuals		10p11.22	Intergenic	NRP1 - NA	ENSG00000099250	""	""	51465		rs7079083-A	rs7079083	0	7079083	intron_variant	1	0.7132	4E-11	10.397940008672	""	0.0142	[0.0099-0.0185] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28678870	rs10767739	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Body mass index	163,835 East Asian ancestry individuals		11p14.1	""	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	130282	21860	rs10767739-G	rs10767739	0	10767739	intergenic_variant	1	0.592219	1E-10	10	""	0.0208134	[0.014-0.027] unit decrease	Illumina [13479178] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28645584	rs4267058	2021-01-26	32376654	Richardson TG	2020-05-06	BMJ	www.ncbi.nlm.nih.gov/pubmed/32376654	Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study.	Body size at age 10	453,169 European ancestry individuals		11p14.1	METTL15	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	96996	55146	rs4267058-T	rs4267058	0	4267058	intergenic_variant	1	0.626467	1E-9	9	""	0.00878598	[0.006-0.0116] unit increase	Affymetrix [12370749]	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28591168	rs11030380	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Alcohol consumption (drinks per week) (MTAG)	up to 1,039,210 European ancestry individuals		11p14.1	NR	METTL15 - NA	ENSG00000169519	""	""	42580		rs11030380-T	rs11030380	0	11030380	intergenic_variant	1	0.6	3E-6	5.52287874528034	""	0.00631481	[0.0037-0.009] unit increase	NR [~ 9732723] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28623873	rs7931440	2022-11-17	36324656	Baselmans B	2021-10-06	Biol Psychiatry Glob Open Sci	www.ncbi.nlm.nih.gov/pubmed/36324656	The Genetic and Neural Substrates of Externalizing Behavior.	Disruptive behavior (multivariate analysis)	523,150 European ancestry individuals		11p14.1	""	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	75285	76857	rs7931440-?	rs7931440	0	7931440	intergenic_variant	1	NR	5E-9	8.30102999566398	""		""	Affymetrix [NR]	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28642653	rs4636654	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		11p14.1	""	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	94065	58077	rs4636654-?	rs4636654	0	4636654	intergenic_variant	1	NR	3E-9	8.52287874528034	""		""	NR [6307410] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28676505	rs10835389	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		11p14.1	""	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	127917	24225	rs10835389-T	rs10835389	0	10835389	intergenic_variant	1	0.6491	4E-18	17.397940008672	""	0.00951453	[0.0074-0.0117] unit decrease	Illumina [10675380] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28642653	rs4636654	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		11p14.1	Intergenic	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	94065	58077	rs4636654-A	rs4636654	0	4636654	intergenic_variant	1	0.3982	4E-8	7.39794000867204	(MTAG)	0.0128	[0.0083-0.0173] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28602221	rs2585817	2021-05-19	33082346	Xu K	2020-10-20	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/33082346	Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals.	Smoking initiation	842,717 European ancestry individuals		11p14.1	MIR8068, LINC01616	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	53633	98509	rs2585817-G	rs2585817	0	2585817	intergenic_variant	1	""	5E-9	8.30102999566398	""	0.979	[NR]	Affymetrix [up to 79000000] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28676861	rs4923555	2019-03-18	30643258	Karlsson Linner R	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643258	Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.	Risk-taking tendency (4-domain principal component model)	315,894 European ancestry individuals		11p14.1	METTL15	NA - LINC02758	""	ENSG00000248990	""		23869	rs4923555-A	rs4923555	0	4923555	intergenic_variant	1	0.655	1E-9	9	""	0.016412318	[0.011-0.022] unit increase	Affymetrix [~ 11515000] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28644626	rs11030391	2020-10-30	33045005	Vogelezang S	2020-10-12	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/33045005	Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits.	Childhood body mass index	39,620 European ancestry individuals		11p14.1	METTL15	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	96038	56104	rs11030391-A	rs11030391	0	11030391	intergenic_variant	1	0.63	5E-7	6.30102999566398	""	0.04	[0.024-0.056] unit increase	Affymetrix, Illumina [8227808] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28602221	rs2585817	2019-03-18	30643258	Karlsson Linner R	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643258	Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.	Smoking status (ever vs never smokers)	518,633 European ancestry individuals		11p14.1	METTL15	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	53633	98509	rs2585817-A	rs2585817	0	2585817	intergenic_variant	1	0.6181	5E-13	12.301029995664	""	0.014932894	[0.011-0.019] unit increase	Affymetrix [11514654] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28668416	rs6484385	2020-05-28	32231278	Hysi PG	2020-03-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32231278	Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia.	Refractive error	542,934 European ancestry individuals		11p14.1	METTL15	NA - LINC02758	""	ENSG00000248990	""		32314	rs6484385-?	rs6484385	0	6484385	intergenic_variant	1	""	7E-16	15.1549019599857	""		""	Affymetrix, Illumina [NR] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28656234	rs7942417	2021-11-02	34446935	Karlsson Linner R	2021-08-26	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/34446935	Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.	Externalizing behaviour (multivariate analysis)	up to 53,293 European ancestry Attention-deficit/hyperactivity disorder individuals, up to 164,684 European ancestry problematic alcohol use individuals, up to 186,875 European ancestry lifetime cannabis use individuals, up to 357,187 European ancestry individuals measuring  reverse-coded age at first sexual intercourse, up to 336,121 European ancestry individuals measuring number of sexual partners, up to 426,379 European ancestry individuals measuring general risk tolerance, up to 1,251,809  European ancestry individuals measuring lifetime smoking initiation		11p14.1	""	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	107646	44496	rs7942417-C	rs7942417	0	7942417	intergenic_variant	1	0.654	5E-20	19.301029995664	""	0.011	[0.009-0.013] unit increase	NR [NR] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28680143	rs2356013	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Weight	165,419 East Asian ancestry individuals		11p14.1	""	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	131555	20587	rs2356013-C	rs2356013	0	2356013	regulatory_region_variant	1	0.591672	2E-11	10.698970004336	""	0.0184851	[0.013-0.024] unit decrease	Illumina [13479924] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28671629	rs10835387	2021-07-27	34211149	Mills MC	2021-07-01	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/34211149	Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour.	Age at first sexual intercourse	397,338 European ancestry individuals		11p14.1	MIR8068	NA - LINC02758	""	ENSG00000248990	""		29101	rs10835387-G	rs10835387	0	10835387	intergenic_variant	1	0.655432	7E-14	13.1549019599857	""	0.0161168	[0.012-0.02] unit decrease	NR [16516521] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28648185	rs7931459	2019-09-18	31151762	Gelernter J	2019-04-08	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/31151762	Genome-wide Association Study of Maximum Habitual Alcohol Intake in >140,000 U.S. European and African American Veterans Yields Novel Risk Loci.	Maximum habitual alcohol consumption	126,936 European ancestry individuals, 17,029 African American individuals		11p14.1	LOC105376602	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	99597	52545	rs7931459-?	rs7931459	0	7931459	intergenic_variant	1	NR	5E-8	7.30102999566398	""	5.465	NR z score decrease	Affymetrix [up to 6007810] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28642320	rs10767733	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Feeling tense	371,318 European ancestry individuals		11p14.1	NR	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	93732	58410	rs10767733-A	rs10767733	0	10767733	regulatory_region_variant	1	0.402825	4E-10	9.39794000867204	""	6.27	z score decrease	NR [10847151] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28591587	rs7127383	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Cigarettes smoked per day (MTAG)	up to 403,928 European ancestry individuals		11p14.1	NR	METTL15 - NA	ENSG00000169519	""	""	42999		rs7127383-T	rs7127383	0	7127383	intergenic_variant	1	0.602	2E-8	7.69897000433602	""	0.0126262	[0.0083-0.017] unit increase	NR [9732723] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28642653	rs4636654	2021-07-27	33479212	Yao X	2021-01-21	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/33479212	Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders.	Neuropsychiatric disorders	19,099 European ancestry attention deficit hyperactivity disorder cases, 18,381 European ancestry autism spectrum disorder cases, 20,352 European ancestry bipolar disorder cases, 170,756 European ancestry major depressive disorder cases, 33,640 European ancestry schizophrenia cases, 466,420 European ancestry controls		11p14.1	NR	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	94065	58077	rs4636654-A	rs4636654	0	4636654	intergenic_variant	1	NR	3E-9	8.52287874528034	""	5.928	NR z score decrease	NR [NR]	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28642381	rs10767734	2018-10-10	30054594	MacGregor S	2018-07-27	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30054594	Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma.	Intraocular pressure	133,492 European ancestry individuals		11p14.1	MIR8068	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	93793	58349	rs10767734-?	rs10767734	0	10767734	regulatory_region_variant	1	NR	4E-8	7.39794000867204	""	0.0725	[0.047-0.098] unit increase	Affymetrix, Illumina [up to 40000000] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28666538	rs7933262	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		11p14.1	Intergenic	NA - LINC02758	""	ENSG00000248990	""		34192	rs7933262-T	rs7933262	0	7933262	intergenic_variant	1	0.3515	9E-10	9.04575749056067	(MTAG)	0.0084	[0.0057-0.0111] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28642561	rs10767735	2022-09-27	35396580	Trubetskoy V	2022-04-08	Nature	www.ncbi.nlm.nih.gov/pubmed/35396580	Mapping genomic loci implicates genes and synaptic biology in schizophrenia.	Schizophrenia	53,386 European ancestry cases, 77,258 European ancestry controls, 14,004 East Asian ancestry cases, 16,757 East Asian ancestry controls, 6,152 African American cases, 3,918 African American controls, 1,234 Latino cases, 3,090 Latino controls	1,979 European ancestry cases, 142,626 European ancestry controls	11p14.1	""	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	93973	58169	rs10767735-G	rs10767735	0	10767735	intergenic_variant	1	0.551	5E-11	10.301029995664	""	1.05096	[1.04-1.07]	Affymetrix [7585078] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28607245	rs7952220	2020-10-07	32606422	Wu Y	2020-06-30	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/32606422	Multi-trait analysis for genome-wide association study of five psychiatric disorders.	Attention deficit hyperactivity disorder (MTAG)	61,421 individuals		11p14.1	NR	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	58657	93485	rs7952220-?	rs7952220	0	7952220	intergenic_variant	1	""	1E-8	8	""		""	NR [520857]	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28642653	rs4636654	2021-07-27	33479212	Yao X	2021-01-21	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/33479212	Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders.	Major depressive disorder (MTAG)	at least 170,756 European ancestry cases, at least 329,443 European ancestry controls		11p14.1	RP11-960D24.1, METTL15	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	94065	58077	rs4636654-A	rs4636654	0	4636654	intergenic_variant	1	0.3974	3E-10	9.52287874528034	""	0.026659915	[0.018-0.035] unit decrease	NR [NR]	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28652996	rs4275621	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Smoking initiation (ever regular vs never regular)	up to 1,232,091 European ancestry individuals		11p14.1	NR	NA - LINC02758	""	ENSG00000248990	""		47734	rs4275621-G	rs4275621	0	4275621	intergenic_variant	1	0.382	4E-16	15.397940008672	(Conditioned on chr11:27679916)	0.021367403	[0.016-0.027] unit decrease	NR [~ 10000000] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28642561	rs10767735	2018-07-19	29662059	Howard DM	2018-04-16	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29662059	Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.	Depression (broad)	113,769 British ancestry cases, 208,811 British ancestry controls		11p14.1	NR	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	93973	58169	rs10767735-C	rs10767735	0	10767735	intergenic_variant	1	0.3949	7E-7	6.15490195998574	""	0.006	[0.0036-0.0084] unit decrease	NR [7666894] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28642653	rs4636654	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		11p14.1	ENSG00000248990	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	94065	58077	rs4636654-A	rs4636654	0	4636654	intergenic_variant	1	NR	2E-8	7.69897000433602	""	5.64	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28630746	rs59617050	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Smoking cessation (MTAG)	up to 820,192 European ancestry individuals		11p14.1	NR	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	82158	69984	rs59617050-G	rs59617050	0	59617050	intergenic_variant	1	0.398	6E-13	12.2218487496164	""	0.0113382	[0.0083-0.0144] unit decrease	NR [9732723] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28687766	rs4923556	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		11p14.1	Intergenic	NA - LINC02758	""	ENSG00000248990	""		12964	rs4923556-T	rs4923556	0	4923556	intergenic_variant	1	0.6512	2E-8	7.69897000433602	(MTAG)	0.0098	[0.0065-0.0131] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28652996	rs4275621	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Smoking initiation (ever regular vs never regular) (MTAG)	up to 1,359,002 European ancestry individuals		11p14.1	NR	NA - LINC02758	""	ENSG00000248990	""		47734	rs4275621-G	rs4275621	0	4275621	intergenic_variant	1	0.382	2E-16	15.698970004336	""	0.00914483	[0.007-0.0113] unit decrease	NR [9732723] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28652996	rs4275621	2019-04-09	30478444	Demontis D	2018-11-26	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30478444	Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder.	Attention deficit hyperactivity disorder	19,099 European ancestry cases, 72 non-European ancestry cases, 1,012 Han Chinese ancestry cases, 34,194 European ancestry controls, 72 non-European ancestry controls, 925 Han Chinese ancestry controls	5,085 Icelandic ancestry cases, 5,857 cases, 131,122 Icelandic ancestry controls, 70,393 controls	11p14.1	intergenic	NA - LINC02758	""	ENSG00000248990	""		47734	rs4275621-A	rs4275621	0	4275621	intergenic_variant	1	NR	3E-9	8.52287874528034	""	1.081081	NR	Affymetrix, Illumina, Perlegen [8047421] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28656064	rs7942078	2019-03-18	30643258	Karlsson Linner R	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643258	Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.	Number of sexual partners	370,711 European ancestry individuals		11p14.1	METTL15	NA - LINC02758	""	ENSG00000248990	""		44666	rs7942078-A	rs7942078	0	7942078	intergenic_variant	1	0.6552	2E-8	7.69897000433602	""	0.01390723	[0.009-0.0188] unit increase	Affymetrix [11515109] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28656234	rs7942417	2022-11-17	36324656	Baselmans B	2021-10-06	Biol Psychiatry Glob Open Sci	www.ncbi.nlm.nih.gov/pubmed/36324656	The Genetic and Neural Substrates of Externalizing Behavior.	Risk-taking behavior (multivariate analysis)	1,506,537 European ancestry individuals		11p14.1	""	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	107646	44496	rs7942417-?	rs7942417	0	7942417	intergenic_variant	1	NR	3E-13	12.5228787452803	""		""	NR [NR]	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28642381	rs10767734	2018-05-11	29617998	Gao XR	2018-03-28	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/29617998	Genome-Wide Association Analyses Identify New Loci Influencing Intraocular Pressure.	Intraocular pressure	115,486 European ancestry individuals		11p14.1	MIR8068, LINC01616	METTL15 - LINC02758	ENSG00000169519	ENSG00000248990	""	93793	58349	rs10767734-C	rs10767734	0	10767734	regulatory_region_variant	1	0.6317	1E-8	8	""	0.079	[0.051-0.107] unit decrease	Affymetrix [~ 11900000] (imputed)	N
rs10767733	11	28642320	A	G	0.399602	1.40666537411e-08	-0.00538947682077	0.0009500934581	138	11	28652996	rs4275621	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Age of smoking initiation (MTAG)	up to 931,815 European ancestry  individuals		11p14.1	NR	NA - LINC02758	""	ENSG00000248990	""		47734	rs4275621-G	rs4275621	0	4275621	intergenic_variant	1	0.376	2E-8	7.69897000433602	""	0.00847247	[0.0055-0.0114] unit increase	NR [9732723] (imputed)	N
rs11137818	9	81356759	A	G	0.468191	7.32753283791e-19	0.00854387660689	0.000963254367502	121	9	81369470	rs11137826	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Body mass index	359,983 European ancestry individuals, 163,835 East Asian ancestry individuals		9q21.31	""	MTND2P8 - KRT18P24	ENSG00000237257	ENSG00000226234	""	11810	281859	rs11137826-T	rs11137826	0	11137826	intergenic_variant	1	NR	5E-9	8.30102999566398	""	0.0112	[0.0075-0.0149] unit decrease	Affymetrix, Illumina [20538802] (imputed)	N
rs11137818	9	81356759	A	G	0.468191	7.32753283791e-19	0.00854387660689	0.000963254367502	121	9	81351608	rs10867245	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		9q21.31	""	PSAT1 - MTND2P8	ENSG00000135069	ENSG00000237257	""	406599	5028	rs10867245-C	rs10867245	0	10867245	intergenic_variant	1	0.546	2E-8	7.69897000433602	""	0.00592589	[0.0039-0.008] unit increase	Illumina [10675380] (imputed)	N
rs11137818	9	81356759	A	G	0.468191	7.32753283791e-19	0.00854387660689	0.000963254367502	121	9	81334684	rs1634350	2019-11-05	30239722	Pulit SL	2018-09-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/30239722	Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry.	Body mass index	806,834 European ancestry individuals		9q21.31		NA - MTND2P8	""	ENSG00000237257	""		21952	rs1634350-A	rs1634350	0	1634350	intergenic_variant	1	0.4355	3E-11	10.5228787452803	""	0.0114	[0.0081-0.0147] unit increase	NR [~ 27400000] (imputed)	N
rs11137818	9	81356759	A	G	0.468191	7.32753283791e-19	0.00854387660689	0.000963254367502	121	9	81334684	rs1634350	2020-04-17	31669095	Zhu Z	2019-10-24	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/31669095	Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank.	Body mass index	457,822 European ancestry individuals		9q21.31	NR	NA - MTND2P8	""	ENSG00000237257	""		21952	rs1634350-?	rs1634350	0	1634350	intergenic_variant	1	NR	8E-12	11.0969100130081	""		""	Affymetrix [~ 8270000] (imputed)	N
rs11193768	10	109651419	T	C	0.250497	2.49306955701e-08	-0.00614338180627	0.00110219812725	134	10	109674913	rs10884570	2022-03-10	34732054	Yang Y	2021-11-04	Circ Genom Precis Med	www.ncbi.nlm.nih.gov/pubmed/34732054	Identification of Functional Genetic Determinants of Cardiac Troponin T and I in a Multiethnic Population and Causal Associations With Atrial Fibrillation.	High-sensitivity cardiac troponin T levels	3,806 African American individuals		10q25.1	""	LINC01435	""	""	ENSG00000229981			rs10884570-?	rs10884570	0	10884570	intron_variant	0	NR	4E-6	5.39794000867204	""	0.11	[0.063-0.157] unit increase	Affymetrix, Illumina [NR] (imputed)	N
rs11193768	10	109651419	T	C	0.250497	2.49306955701e-08	-0.00614338180627	0.00110219812725	134	10	109673106	rs10884569	2018-09-20	30019117	Liu J	2018-07-17	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30019117	The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.	Adolescent idiopathic scoliosis	196 cases, 303 controls		10q25.1	NR	LINC01435	""	""	ENSG00000229981			rs10884569-?	rs10884569	0	10884569	intron_variant	0	NR	4E-23	22.397940008672	""		""	Affymetrix [NR]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57396825	rs7102271	2018-11-16	30072576	Emilsson V	2018-08-02	Science	www.ncbi.nlm.nih.gov/pubmed/30072576	Co-regulatory networks of human serum proteins link genetics to disease.	Blood protein levels	3,200 European ancestry individuals		11q12.1	NR	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	10181	11846	rs7102271-G	rs7102271	0	7102271	intergenic_variant	1	0.74171875	8E-29	28.0969100130081	(C1R, 3285_23_2)	0.31410298	[0.26-0.37] unit increase	Illumina [> 1000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57404779	rs10750866	2022-08-05	35835914	Watanabe K	2022-07-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35835914	Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.	Insomnia	593,724 European ancestry cases, 1,771,286 European ancestry controls		11q12.1	""	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	18135	3892	rs10750866-A	rs10750866	0	10750866	upstream_gene_variant	1	NR	4E-13	12.397940008672	""	0.007	[0.005-0.009] unit decrease	Illumina [10713943] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57371918	rs28362950	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Mean platelet volume	484,042 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals		11q12.1	NR	SERPING1	""	""	ENSG00000149131			rs28362950-G	rs28362950	0	28362950	intron_variant	0	0.738953	3E-37	36.5228787452803	""		""	Affymetrix, Illumina [17210439] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57396825	rs7102271	2018-11-16	30072576	Emilsson V	2018-08-02	Science	www.ncbi.nlm.nih.gov/pubmed/30072576	Co-regulatory networks of human serum proteins link genetics to disease.	Blood protein levels	3,200 European ancestry individuals		11q12.1	NR	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	10181	11846	rs7102271-G	rs7102271	0	7102271	intergenic_variant	1	0.74171875	2E-10	9.69897000433602	(MASP1, 8091_16_3)	0.18068555	[0.13-0.24] unit increase	Illumina [> 1000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57411742	rs2081361	2021-11-01	34668383	Leskela J	2021-10-20	J Am Heart Assoc	www.ncbi.nlm.nih.gov/pubmed/34668383	Genetic Profile of Endotoxemia Reveals an Association With Thromboembolism and Stroke.	Serum lipopolysaccharide activity	11,296 European ancestry individuals		11q12.1	NR	MIR130A - YPEL4	ENSG00000208009	ENSG00000166793	""	2983	818	rs2081361-C	rs2081361	0	2081361	intron_variant	1	0.7023	4E-9	8.39794000867204	""	0.0864	[0.058-0.115] unit increase	Affymetrix, Illumina [9900000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57396825	rs7102271	2018-11-16	30072576	Emilsson V	2018-08-02	Science	www.ncbi.nlm.nih.gov/pubmed/30072576	Co-regulatory networks of human serum proteins link genetics to disease.	Blood protein levels	3,200 European ancestry individuals		11q12.1	NR	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	10181	11846	rs7102271-G	rs7102271	0	7102271	intergenic_variant	1	0.74171875	3E-19	18.5228787452803	(CDH12, 8329_166_3)	0.252777	[0.2-0.31] unit decrease	Illumina [> 1000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57396825	rs7102271	2018-11-16	30072576	Emilsson V	2018-08-02	Science	www.ncbi.nlm.nih.gov/pubmed/30072576	Co-regulatory networks of human serum proteins link genetics to disease.	Blood protein levels	3,200 European ancestry individuals		11q12.1	NR	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	10181	11846	rs7102271-G	rs7102271	0	7102271	intergenic_variant	1	0.74171875	4E-328	327.397940008672	(SERPING1, 13710_6_3)	1.0016209	[0.96-1.05] unit decrease	Illumina [> 1000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57372526	rs28362951	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Platelet count	408,112 British individuals		11q12.1	SERPING1	SERPING1	""	""	ENSG00000149131			rs28362951-G	rs28362951	0	28362951	intron_variant	0	0.267719	3E-16	15.5228787452803	""	0.020990534	[0.016-0.026] unit increase	Affymetrix [93095623] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57374332	rs11603020	2022-04-11	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	Plasma protease C1 inhibitor levels	997 European ancestry individuals	338 Greater Middle Eastern (Middle Eastern, North African or Persian), South Asian ancestry, Asian ancestry individuals	11q12.1	""	SERPING1	""	""	ENSG00000149131			rs11603020-C	rs11603020	0	11603020	intron_variant	0	NR	5E-96	95.301029995664	""	0.936	[0.86-1.01] unit decrease	Affymetrix [509946]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57376131	rs138770460	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Platelet count	542,827 European ancestry individuals		11q12.1	NR	SERPING1	""	""	ENSG00000149131			rs138770460-A	rs138770460	0	138770460	intron_variant	0	0.269909	2E-24	23.698970004336	""	0.021054	[0.017-0.025] SD unit increase	Affymetrix, Illumina [50241410] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57404779	rs10750866	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Worry too long after an embarrassing experience	367,725 European ancestry individuals		11q12.1	SMTNL1	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	18135	3892	rs10750866-A	rs10750866	0	10750866	upstream_gene_variant	1	0.272951	1E-11	11	""	6.78	z score decrease	NR [10847151] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57404779	rs10750866	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		11q12.1	Intergenic	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	18135	3892	rs10750866-A	rs10750866	0	10750866	upstream_gene_variant	1	0.7309	9E-15	14.0457574905607	(MTAG)	0.02	[0.015-0.025] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57371192	rs76525968	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Lung function (FEV1/FVC)	approximately 370,000 European ancestry individuals		11q12.1	""	SERPING1	""	""	ENSG00000149131			rs76525968-?	rs76525968	0	76525968	non_coding_transcript_exon_variant	0	NR	2E-11	10.698970004336	""		""	NR [~ 8900000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57404779	rs10750866	2022-08-05	35835914	Watanabe K	2022-07-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35835914	Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.	Insomnia	390,751 European ancestry female cases, 1,018,386 European ancestry female controls		11q12.1	""	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	18135	3892	rs10750866-A	rs10750866	0	10750866	upstream_gene_variant	1	NR	5E-10	9.30102999566398	""	0.008	[0.006-0.01] unit decrease	Illumina [10288913] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57399072	rs11229077	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Mean platelet volume	460,935 European ancestry individuals		11q12.1	NR	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	12428	9599	rs11229077-C	rs11229077	0	11229077	intergenic_variant	1	0.728865	9E-40	39.0457574905607	""	0.02862	[0.024-0.033] SD unit increase	Affymetrix, Illumina [49660172] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57376131	rs138770460	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Platelet count	721,201 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals		11q12.1	NR	SERPING1	""	""	ENSG00000149131			rs138770460-A	rs138770460	0	138770460	intron_variant	0	0.228782	4E-23	22.397940008672	""		""	Affymetrix, Illumina [24588908] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57381263	rs10896631	2022-10-24	36168886	Thareja G	2022-09-28	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/36168886	Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.	Plasma protease C1 inhibitor levels	2,935 Qatari ancestry individuals		11q12.1	""	SERPING1	""	""	ENSG00000149131			rs10896631-C	rs10896631	0	10896631	intron_variant	0	0.244974	1E-132	132	""	0.772698	[0.71-0.83] unit decrease	NR [10004359]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57371911	rs28362949	2022-09-27	34814699	Katz DH	2021-11-24	Circulation	www.ncbi.nlm.nih.gov/pubmed/34814699	Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease.	Plasma protease C1 inhibitor levels	1,852 African American or Afro-Caribbean individuals	1,688 African American or Afro-Caribbean, Hispanic or Latin American, Asian ancestry, European ancestry individuals	11q12.1	""	SERPING1	""	""	ENSG00000149131			rs28362949-?	rs28362949	0	28362949	intron_variant	0	NR	1E-96	96	""	0.8	[0.72-0.88] unit decrease	Illumina [NR]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57369730	rs11229063	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Serum alkaline phosphatase levels	344,292 European ancestry individuals, 118,886 East Asian ancestry individuals		11q12.1	""	SERPING1	""	""	ENSG00000149131			rs11229063-A	rs11229063	0	11229063	non_coding_transcript_exon_variant	0	NR	1E-8	8	""	0.0139	[0.0092-0.0186] unit decrease	Affymetrix, Illumina [20533886] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57404779	rs10750866	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		11q12.1	NR	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	18135	3892	rs10750866-?	rs10750866	0	10750866	upstream_gene_variant	1	NR	4E-6	5.39794000867204	""	4.614	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57384519	rs34052104	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Mean platelet volume	408,112 British individuals		11q12.1	SERPING1	SERPING1	""	""	ENSG00000149131			rs34052104-C	rs34052104	0	34052104	intron_variant	0	0.269858	7E-27	26.1549019599857	""	0.027522424	[0.022-0.033] unit decrease	Affymetrix [93095623] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57399511	rs11229080	2018-11-16	30072576	Emilsson V	2018-08-02	Science	www.ncbi.nlm.nih.gov/pubmed/30072576	Co-regulatory networks of human serum proteins link genetics to disease.	Blood protein levels	3,200 European ancestry individuals		11q12.1	NR	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	12867	9160	rs11229080-T	rs11229080	0	11229080	intergenic_variant	1	0.74171875	3E-19	18.5228787452803	(CDH12, 8329_166_3)	0.252777	[0.2-0.31] unit decrease	Illumina [> 1000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57370742	rs78364821	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Platelet count	350,474 European ancestry individuals, 148,623 East Asian ancestry individuals		11q12.1	""	SERPING1	""	""	ENSG00000149131			rs78364821-T	rs78364821	0	78364821	non_coding_transcript_exon_variant	0	NR	6E-19	18.2218487496164	""	0.0233	[0.018-0.028] unit increase	Affymetrix, Illumina [20538505] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57391023	rs11229075	2022-02-15	35078996	Gudjonsson A	2022-01-25	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/35078996	A genome-wide association study of serum proteins reveals shared loci with common diseases.	Serum levels of protein MASP1	5,365 Icelandic ancestry individuals		11q12.1	""	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	4379	17648	rs11229075-C	rs11229075	0	11229075	intergenic_variant	1	0.2529	6E-14	13.2218487496164	""	0.165079	[0.12-0.21] unit decrease	Illumina [7506463] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57369730	rs11229063	2022-02-15	35078996	Gudjonsson A	2022-01-25	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/35078996	A genome-wide association study of serum proteins reveals shared loci with common diseases.	Serum levels of protein C1R	5,362 Icelandic ancestry individuals		11q12.1	""	SERPING1	""	""	ENSG00000149131			rs11229063-A	rs11229063	0	11229063	non_coding_transcript_exon_variant	0	0.2456	6E-52	51.2218487496164	""	0.329636	[0.29-0.37] unit decrease	Illumina [7506463] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57399511	rs11229080	2018-11-16	30072576	Emilsson V	2018-08-02	Science	www.ncbi.nlm.nih.gov/pubmed/30072576	Co-regulatory networks of human serum proteins link genetics to disease.	Blood protein levels	3,200 European ancestry individuals		11q12.1	NR	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	12867	9160	rs11229080-T	rs11229080	0	11229080	intergenic_variant	1	0.74171875	2E-178	177.698970004336	(SERPING1, 4479_14_2)	0.74958706	[0.7-0.8] unit increase	Illumina [> 1000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57391023	rs11229075	2018-07-05	29875488	Sun BB	2018-06-06	Nature	www.ncbi.nlm.nih.gov/pubmed/29875488	Genomic atlas of the human plasma proteome.	Blood protein levels	3,301 European ancestry individuals		11q12.1	SERPING1	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	4379	17648	rs11229075-C	rs11229075	0	11229075	intergenic_variant	1	0.261	1E-119	119	(Plasma protease C1 inhibitor, SERPING1.4479.14.2)	0.6	[0.54-0.66] unit decrease	Affymetrix [10572788] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57396825	rs7102271	2018-11-16	30072576	Emilsson V	2018-08-02	Science	www.ncbi.nlm.nih.gov/pubmed/30072576	Co-regulatory networks of human serum proteins link genetics to disease.	Blood protein levels	3,200 European ancestry individuals		11q12.1	NR	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	10181	11846	rs7102271-G	rs7102271	0	7102271	intergenic_variant	1	0.74171875	2E-178	177.698970004336	(SERPING1, 4479_14_2)	0.74958706	[0.7-0.8] unit increase	Illumina [> 1000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57369730	rs11229063	2022-02-15	35078996	Gudjonsson A	2022-01-25	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/35078996	A genome-wide association study of serum proteins reveals shared loci with common diseases.	Serum levels of protein DVL2	5,357 Icelandic ancestry individuals		11q12.1	""	SERPING1	""	""	ENSG00000149131			rs11229063-A	rs11229063	0	11229063	non_coding_transcript_exon_variant	0	0.2456	3E-16	15.5228787452803	""	0.177457	[0.13-0.22] unit decrease	Illumina [7506463] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57391023	rs11229075	2022-02-15	35078996	Gudjonsson A	2022-01-25	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/35078996	A genome-wide association study of serum proteins reveals shared loci with common diseases.	Serum levels of protein CDH12	5,367 Icelandic ancestry individuals		11q12.1	""	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	4379	17648	rs11229075-C	rs11229075	0	11229075	intergenic_variant	1	0.2529	1E-35	35	""	0.272194	[0.23-0.32] unit increase	Illumina [7506463] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57401400	rs73480560	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Feeling hurt	372,047 European ancestry individuals		11q12.1	SMTNL1	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	14756	7271	rs73480560-T	rs73480560	0	73480560	intergenic_variant	1	0.260712	2E-8	7.69897000433602	""	5.6	z score increase	NR [10847151] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57399511	rs11229080	2018-11-16	30072576	Emilsson V	2018-08-02	Science	www.ncbi.nlm.nih.gov/pubmed/30072576	Co-regulatory networks of human serum proteins link genetics to disease.	Blood protein levels	3,200 European ancestry individuals		11q12.1	NR	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	12867	9160	rs11229080-T	rs11229080	0	11229080	intergenic_variant	1	0.74171875	8E-29	28.0969100130081	(C1R, 3285_23_2)	0.31410298	[0.26-0.37] unit increase	Illumina [> 1000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57399511	rs11229080	2018-11-16	30072576	Emilsson V	2018-08-02	Science	www.ncbi.nlm.nih.gov/pubmed/30072576	Co-regulatory networks of human serum proteins link genetics to disease.	Blood protein levels	3,200 European ancestry individuals		11q12.1	NR	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	12867	9160	rs11229080-T	rs11229080	0	11229080	intergenic_variant	1	0.74171875	2E-10	9.69897000433602	(MASP1, 8091_16_3)	0.18068555	[0.13-0.24] unit increase	Illumina [> 1000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57399511	rs11229080	2018-11-16	30072576	Emilsson V	2018-08-02	Science	www.ncbi.nlm.nih.gov/pubmed/30072576	Co-regulatory networks of human serum proteins link genetics to disease.	Blood protein levels	3,200 European ancestry individuals		11q12.1	NR	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	12867	9160	rs11229080-T	rs11229080	0	11229080	intergenic_variant	1	0.74171875	4E-328	327.397940008672	(SERPING1, 13710_6_3)	1.0016209	[0.96-1.05] unit decrease	Illumina [> 1000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57401400	rs73480560	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Neuroticism	449,484 European ancestry individuals		11q12.1	NR	SERPING1 - MIR130A	ENSG00000149131	ENSG00000208009	""	14756	7271	rs73480560-T	rs73480560	0	73480560	intergenic_variant	1	NR	2E-9	8.69897000433602	""	5.991	z score increase	Affymetrix [10847151] (imputed)	N
rs11635618	15	83508931	G	T	0.459245	1.25177498194e-08	-0.00529281810517	0.000929784622198	171	15	83508278	rs4778691	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		15q25.2	""	HOMER2	""	""	ENSG00000103942			rs4778691-A	rs4778691	0	4778691	3_prime_UTR_variant	0	0.483	5E-12	11.301029995664	""	0.00722358	[0.0052-0.0093] unit decrease	Illumina [10675380] (imputed)	N
rs11635618	15	83508931	G	T	0.459245	1.25177498194e-08	-0.00529281810517	0.000929784622198	171	15	83508931	rs11635618	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		15q25.2	NR	HOMER2	""	""	ENSG00000103942			rs11635618-?	rs11635618	0	11635618	3_prime_UTR_variant	0	NR	4E-6	5.39794000867204	""	4.617	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs11635618	15	83508931	G	T	0.459245	1.25177498194e-08	-0.00529281810517	0.000929784622198	171	15	83514599	rs7182990	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Lung function (FVC)	approximately 372,000 European ancestry individuals		15q25.2	""	HOMER2	""	""	ENSG00000103942			rs7182990-?	rs7182990	0	7182990	3_prime_UTR_variant	0	NR	9E-14	13.0457574905607	""		""	NR [~ 8900000] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133324567	rs12540206	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		7q33	""	EXOC4	""	""	ENSG00000131558			rs12540206-?	rs12540206	0	12540206	intron_variant	0	NR	3E-9	8.52287874528034	""		""	NR [6307410] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127082497	rs4731365	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		7q31.33	NR	ZNF800 - GCC1	ENSG00000048405	ENSG00000179562	""	10519	138185	rs4731365-A	rs4731365	0	4731365	intergenic_variant	1	NR	6E-12	11.2218487496164	""	6.883	z-score decrease	Affymetrix, Illumina [9295118] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127102681	rs61544985	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		7q31.33	AC000124.1	ZNF800 - NA	ENSG00000048405	""	""	30703		rs61544985-A	rs61544985	0	61544985	intergenic_variant	1	NR	1E-11	11	""	6.753	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127147628	rs12671806	2021-06-29	32895543	de la Fuente J	2020-09-07	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/32895543	A general dimension of genetic sharing across diverse cognitive traits inferred from molecular data.	Verbal-numerical reasoning	171,304 British ancestry individuals		7q32.1	""	ZNF800 - GCC1	ENSG00000048405	ENSG00000179562	""	75650	73054	rs12671806-?	rs12671806	0	12671806	intergenic_variant	1	NR	4E-13	12.397940008672	""		""	NR [7857346] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127201664	rs62481355	2016-12-01	26818947	Imamura M	2016-01-28	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/26818947	Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.	Type 2 diabetes	15,463 Japanese ancestry cases, 26,183 Japanese ancestry controls	20,490 East Asian ancestry cases, 22,922 East Asian ancestry controls, 38,947 European ancestry cases, 121,903 European ancestry controls, 10,587 South Asian ancestry cases, 14,378 South Asian ancestry controls, 3,848 Mexican/Latino cases, 4,366 Mexican/Latino controls	7q32.1	GCC1	CACNA2D1 - GCC1	ENSG00000153956	ENSG00000179562	""	45117833	19018	rs62481355-T	rs62481355	0	62481355	intergenic_variant	1	NR	3E-7	6.52287874528034	(Japanese)	1.0909	[1.05521-1.12779]	Illumina [7521072] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127174679	rs17150996	2020-05-28	32231278	Hysi PG	2020-03-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32231278	Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia.	Refractive error	542,934 European ancestry individuals		7q32.1	GCC1	NA - GCC1	""	ENSG00000179562	""		46003	rs17150996-?	rs17150996	0	17150996	intergenic_variant	1	""	4E-8	7.39794000867204	""		""	Affymetrix, Illumina [NR] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127082497	rs4731365	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		7q31.33	""	ZNF800 - GCC1	ENSG00000048405	ENSG00000179562	""	10519	138185	rs4731365-?	rs4731365	0	4731365	intergenic_variant	1	NR	2E-10	9.69897000433602	""		""	NR [6307410] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127130001	rs141322890	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		7q31.33	AC000124.1	ZNF800 - GCC1	ENSG00000048405	ENSG00000179562	""	58023	90681	rs141322890-A	rs141322890	0	141322890	intergenic_variant	1	NR	4E-11	10.397940008672	""	0.020602515	[0.014-0.027] unit decrease	Affymetrix [NR]	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127082497	rs4731365	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		7q31.33	NR	ZNF800 - GCC1	ENSG00000048405	ENSG00000179562	""	10519	138185	rs4731365-G	rs4731365	0	4731365	intergenic_variant	1	0.388668	4E-10	9.39794000867204	""	0.04025498	[0.028-0.053] unit increase	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs11635618	15	83508931	G	T	0.459245	1.25177498194e-08	-0.00529281810517	0.000929784622198	171	15	82558802	rs11854289	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		15q25.2	NR	SAXO2	""	""	ENSG00000188659			rs11854289-T	rs11854289	0	11854289	intron_variant	0	NR	4E-8	7.39794000867204	""	5.475	z-score decrease	Affymetrix, Illumina [9295118] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82558802	rs11854289	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		15q25.2	NR	SAXO2	""	""	ENSG00000188659			rs11854289-T	rs11854289	0	11854289	intron_variant	0	NR	4E-8	7.39794000867204	""	5.475	z-score decrease	Affymetrix, Illumina [9295118] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128332084	rs13219424	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		6q22.33	""	PTPRK	""	""	ENSG00000152894			rs13219424-T	rs13219424	0	13219424	intron_variant	0	0.3169	5E-12	11.301029995664	(conditional-joint)	0.0104	[0.0075-0.0133] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128332084	rs13219424	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	Reaction time	330,069 European ancestry individuals		6q22.33	PTPRK	PTPRK	""	""	ENSG00000152894			rs13219424-?	rs13219424	0	13219424	intron_variant	0	NR	1E-8	8	""	0.0098881	[0.0065-0.0133] unit decrease	Affymetrix [805426] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128324030	rs7744108	2022-10-11	35974141	Lahti J	2022-08-16	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35974141	Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.	Verbal short term memory	44,874 European ancestry individuals	8,763 European ancestry individuals	6q22.33	""	PTPRK	""	""	ENSG00000152894			rs7744108-G	rs7744108	0	7744108	intron_variant	0	0.3778	8E-6	5.09691001300806	""	4.458	z score increase	Affymetrix, Illumina [NR] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128332084	rs13219424	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Smoking initiation (ever regular vs never regular) (MTAG)	up to 1,359,002 European ancestry individuals		6q22.33	NR	PTPRK	""	""	ENSG00000152894			rs13219424-T	rs13219424	0	13219424	intron_variant	0	0.314	2E-9	8.69897000433602	""	0.00708586	[0.0048-0.0094] unit decrease	NR [9732723] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128333682	rs13197257	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		6q22.33	""	PTPRK	""	""	ENSG00000152894			rs13197257-T	rs13197257	0	13197257	intron_variant	0	0.279	3E-12	11.5228787452803	""	0.0109	[0.0078-0.014] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128312033	rs12055782	2022-10-11	35974141	Lahti J	2022-08-16	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35974141	Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.	Verbal short term memory	44,874 European ancestry individuals	8,763 European ancestry individuals	6q22.33	""	PTPRK	""	""	ENSG00000152894			rs12055782-G	rs12055782	0	12055782	splice_region_variant	0	0.2939	6E-6	5.22184874961636	""	4.519	z score increase	Affymetrix, Illumina [NR] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128333682	rs13197257	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		6q22.33	NR	PTPRK	""	""	ENSG00000152894			rs13197257-?	rs13197257	0	13197257	intron_variant	0	NR	6E-8	7.22184874961636	""	5.415	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128332084	rs13219424	2021-06-29	32895543	de la Fuente J	2020-09-07	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/32895543	A general dimension of genetic sharing across diverse cognitive traits inferred from molecular data.	Reaction time	330,024 British ancestry individuals		6q22.33	""	PTPRK	""	""	ENSG00000152894			rs13219424-?	rs13219424	0	13219424	intron_variant	0	NR	1E-8	8	""		""	NR [7857346] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128312985	rs6936878	2022-10-11	35974141	Lahti J	2022-08-16	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35974141	Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.	Verbal short term memory	44,874 European ancestry individuals	8,763 European ancestry individuals	6q22.33	""	PTPRK	""	""	ENSG00000152894			rs6936878-C	rs6936878	0	6936878	intron_variant	0	0.2614	7E-6	5.15490195998574	""	4.494	z score increase	Affymetrix, Illumina [NR] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128309768	rs13200150	2019-03-19	30531953	International League Against Epilepsy Consortium on Complex Epilepsies	2018-12-10	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/30531953	Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies.	Generalized epilepsy	3,708 European ancestry cases, 61 African American cases, 24,218 European ancestry controls, 2,584 African American controls		6q22.33	NR	PTPRK	""	""	ENSG00000152894			rs13200150-G	rs13200150	0	13200150	intron_variant	0	0.3	6E-9	8.22184874961636	""	5.82	NR unit decrease	Affymetrix, Illumina [~ 5000000] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128333682	rs13197257	2022-10-26	36150907	Hatoum AS	2022-07-14	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/36150907	Genome-wide Association Study Shows That Executive Functioning Is Influenced by GABAergic Processes and Is a Neurocognitive Genetic Correlate of Psychiatric Disorders.	Common executive function	427,037 European ancestry individuals		6q22.33	""	PTPRK	""	""	ENSG00000152894			rs13197257-?	rs13197257	0	13197257	intron_variant	0	NR	2E-9	8.69897000433602	""		""	Affymetrix [7391068] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128313088	rs3903663	2022-10-11	35974141	Lahti J	2022-08-16	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35974141	Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.	Verbal short term memory	44,874 European ancestry individuals	8,763 European ancestry individuals	6q22.33	""	PTPRK	""	""	ENSG00000152894			rs3903663-G	rs3903663	0	3903663	intron_variant	0	0.2927	6E-6	5.22184874961636	""	4.521	z score increase	Affymetrix, Illumina [NR] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128312033	rs12055782	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		6q22.33	""	PTPRK	""	""	ENSG00000152894			rs12055782-A	rs12055782	0	12055782	splice_region_variant	0	0.7179	4E-24	23.397940008672	""	0.0117761	[0.0095-0.0141] unit decrease	Illumina [10675380] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128327031	rs45582334	2021-11-02	34446935	Karlsson Linner R	2021-08-26	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/34446935	Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.	Externalizing behaviour (multivariate analysis)	up to 53,293 European ancestry Attention-deficit/hyperactivity disorder individuals, up to 164,684 European ancestry problematic alcohol use individuals, up to 186,875 European ancestry lifetime cannabis use individuals, up to 357,187 European ancestry individuals measuring  reverse-coded age at first sexual intercourse, up to 336,121 European ancestry individuals measuring number of sexual partners, up to 426,379 European ancestry individuals measuring general risk tolerance, up to 1,251,809  European ancestry individuals measuring lifetime smoking initiation		6q22.33	""	PTPRK	""	""	ENSG00000152894			rs45582334-A	rs45582334	0	45582334	intron_variant	0	0.691	8E-10	9.09691001300806	""	0.008	[0.006-0.01] unit increase	NR [NR] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128332084	rs13219424	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		6q22.33	Intergenic	PTPRK	""	""	ENSG00000152894			rs13219424-T	rs13219424	0	13219424	intron_variant	0	0.3169	7E-15	14.1549019599857	(MTAG)	0.011	[0.0083-0.0137] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128332084	rs13219424	2022-09-27	35396580	Trubetskoy V	2022-04-08	Nature	www.ncbi.nlm.nih.gov/pubmed/35396580	Mapping genomic loci implicates genes and synaptic biology in schizophrenia.	Schizophrenia	53,386 European ancestry cases, 77,258 European ancestry controls, 14,004 East Asian ancestry cases, 16,757 East Asian ancestry controls, 6,152 African American cases, 3,918 African American controls, 1,234 Latino cases, 3,090 Latino controls	1,979 European ancestry cases, 142,626 European ancestry controls	6q22.33	""	PTPRK	""	""	ENSG00000152894			rs13219424-C	rs13219424	0	13219424	intron_variant	0	0.688	3E-7	6.52287874528034	""	1.04227	[1.03-1.06]	Affymetrix [7585078] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128305888	rs9402011	2022-10-11	35974141	Lahti J	2022-08-16	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35974141	Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.	Verbal short term memory	44,874 European ancestry individuals	8,763 European ancestry individuals	6q22.33	""	PTPRK	""	""	ENSG00000152894			rs9402011-C	rs9402011	0	9402011	intron_variant	0	0.2866	7E-6	5.15490195998574	""	4.492	z score increase	Affymetrix, Illumina [NR] (imputed)	N
rs12055782	6	128312033	G	A	0.290258	2.44858835118e-12	-0.00709549833031	0.00101274404776	89	6	128333682	rs13197257	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		6q22.33	Intergenic	PTPRK	""	""	ENSG00000152894			rs13197257-T	rs13197257	0	13197257	intron_variant	0	0.2747	2E-10	9.69897000433602	(MTAG)	0.0117	[0.0082-0.0152] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs17560772	16	7235901	G	A	0.345924	2.53765854513e-10	0.00607490199419	0.000960508143623	172	16	7265070	rs11865256	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		16p13.3	RBFOX1	RBFOX1	""	""	ENSG00000078328			rs11865256-T	rs11865256	0	11865256	intron_variant	0	NR	1E-8	8	""	5.678	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs12149852	16	81365197	G	A	0.038767	1.24064971896e-76	-1.52349560471	0.0822291768711	180	16	81361484	rs7200201	2022-09-01	31882771	Al-Khelaifi F	2019-12-27	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/31882771	Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance.	4-hydroxyphenylpyruvate levels in elite athletes	490 individuals		16q23.2	""	GAN	""	""	ENSG00000261609			rs7200201-?	rs7200201	0	7200201	intron_variant	0	NR	8E-6	5.09691001300806	""	0.83607036	[0.48-1.2] unit increase	Illumina [275016]	N
rs12663818	6	155897444	C	T	0.131213	5.98757106529e-09	0.00664273647574	0.00114193177519	90	6	155896132	rs9397822	2020-01-29	31844048	Hill WD	2019-12-16	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/31844048	Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income.	Household income (MTAG)	505,541 British and unknown ancestry individuals		6q25.3	RNU7-152P	UBDP1 - RNU7-152P	ENSG00000226365	ENSG00000238789	""	126105192	79965	rs9397822-A	rs9397822	0	9397822	intergenic_variant	1	0.1679	4E-8	7.39794000867204	""	0.014694304	[0.0095-0.0199] unit decrease	Affymetrix [up to 18485882] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133154426	rs1424580	2022-03-15	34743297	Kulminski AM	2021-11-06	Geroscience	www.ncbi.nlm.nih.gov/pubmed/34743297	Pleiotropic predisposition to Alzheimer's disease and educational attainment: insights from the summary statistics analysis.	Alzheimer's disease or educational attainment (pleiotropy)	(see Lambert 2013 and Okbay 2016)		7q33	""	EXOC4	""	""	ENSG00000131558			rs1424580-T	rs1424580	0	1424580	intron_variant	0	0.8004	4E-8	7.39794000867204	""	40.211506	z score increase	NR [6814003]	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133081470	rs6949831	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		7q33	NR	EXOC4	""	""	ENSG00000131558			rs6949831-C	rs6949831	0	6949831	intron_variant	0	NR	9E-10	9.04575749056067	""	6.133	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	132954533	rs12707087	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		7q33	EXOC4	EXOC4	""	""	ENSG00000131558			rs12707087-T	rs12707087	0	12707087	intron_variant	0	NR	2E-9	8.69897000433602	""	0.022929119	[0.015-0.03] unit decrease	Affymetrix [NR]	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133069682	rs11765450	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		7q33	EXOC4	EXOC4	""	""	ENSG00000131558			rs11765450-T	rs11765450	0	11765450	intron_variant	0	NR	4E-10	9.39794000867204	""	0.023339247	[0.016-0.031] unit decrease	Affymetrix [NR]	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133149821	rs1038630	2020-01-29	31844048	Hill WD	2019-12-16	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/31844048	Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income.	Household income (MTAG)	505,541 British and unknown ancestry individuals		7q33	EXOC4	EXOC4	""	""	ENSG00000131558			rs1038630-G	rs1038630	0	1038630	intron_variant	0	0.1903	4E-10	9.39794000867204	""	0.015974015	[0.011-0.021] unit increase	Affymetrix [up to 18485882] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667131	rs3785237	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Neuroticism	449,484 European ancestry individuals		16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs3785237-C	rs3785237	0	3785237	intron_variant	0	NR	4E-14	13.397940008672	""	7.574	z score increase	Affymetrix [10847151] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7673255	rs7186834	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		16p13.3	RBFOX1	RBFOX1	""	""	ENSG00000078328			rs7186834-T	rs7186834	0	7186834	intron_variant	0	NR	5E-9	8.30102999566398	""	5.859	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7673255	rs7186834	2022-09-01	31882771	Al-Khelaifi F	2019-12-27	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/31882771	Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance.	2,3-dihydroxyisovalerate levels in elite athletes	490 individuals		16p13.3	""	RBFOX1	""	""	ENSG00000078328			rs7186834-?	rs7186834	0	7186834	intron_variant	0	NR	8E-6	5.09691001300806	""	0.29075575	[0.16-0.42] unit decrease	Illumina [275016]	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7654531	rs1857952	2022-08-30	32193382	Cole JB	2020-03-19	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/32193382	Comprehensive genomic analysis of dietary habits in UK Biobank identifies hundreds of genetic associations.	Principal component-derived dietary pattern 1	449,210 European ancestry individuals		16p13.3	""	RBFOX1	""	""	ENSG00000078328			rs1857952-A	rs1857952	0	1857952	intron_variant	0	0.454786	3E-11	10.5228787452803	""	0.0315839	[0.022-0.041] unit decrease	NR [NR] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7662489	rs11640647	2017-03-17	27089181	Okbay A	2016-04-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27089181	Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.	Neuroticism	170,911 European ancestry individuals		16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs11640647-T	rs11640647	0	11640647	intron_variant	0	0.602	8E-6	5.09691001300806	""	0.01627837	[0.0091-0.0234] unit increase	Affymetrix [up to 6544775] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7662707	rs12923795	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Worry	348,219 European ancestry individuals		16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs12923795-A	rs12923795	0	12923795	intron_variant	0	NR	6E-10	9.22184874961636	""	0.01476	[0.01-0.019] unit decrease	Affymetrix [10847151] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7670999	rs3785229	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		16p13.3	Intergenic	RBFOX1	""	""	ENSG00000078328			rs3785229-A	rs3785229	0	3785229	intron_variant	0	0.468	2E-9	8.69897000433602	(MTAG)	0.0099	[0.0066-0.0132] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667131	rs3785237	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Neurociticism	380,506 European ancestry individuals		16p13.3	RBFOX1	RBFOX1	""	""	ENSG00000078328			rs3785237-C	rs3785237	0	3785237	intron_variant	0	0.496839	7E-13	12.1549019599857	""	7.18	z score increase	NR [10847151] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7665170	rs34518736	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		16p13.3	Intergenic	RBFOX1	""	""	ENSG00000078328			rs34518736-C	rs34518736	0	34518736	intron_variant	0	0.4514	1E-12	12	(MTAG)	0.0164	[0.012-0.021] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7665170	rs34518736	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		16p13.3	Intergenic	RBFOX1	""	""	ENSG00000078328			rs34518736-C	rs34518736	0	34518736	intron_variant	0	0.4538	9E-14	13.0457574905607	(MTAG)	0.0098	[0.0073-0.0123] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667131	rs3785237	2020-07-07	31972866	Nagel M	2020-01-23	Acta Psychiatr Scand	www.ncbi.nlm.nih.gov/pubmed/31972866	Genome-wide association study of the sensitivity to environmental stress and adversity (SESA) neuroticism cluster.	Sensitivity to environmental stress and adversity	351,827 European ancestry individuals		16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs3785237-G	rs3785237	0	3785237	intron_variant	0	NR	1E-11	11	""	0.01594	NR unit decrease	NR [7259579]	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7654082	rs11644336	2022-07-04	33462482	Ruhlemann MC	2021-01-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33462482	Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome.	G_Bacteroidetes abundance	8,956 German ancestry individuals		16p13.3	""	RBFOX1	""	""	ENSG00000078328			rs11644336-?	rs11644336	0	11644336	intron_variant	0	NR	4E-6	5.39794000867204	""	0.14826569	[0.086-0.211] unit decrease	NR [6900000] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7668480	rs11077207	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		16p13.3	RBFOX1	RBFOX1	""	""	ENSG00000078328			rs11077207-C	rs11077207	0	11077207	intron_variant	0	NR	3E-10	9.52287874528034	""	0.018427402	[0.013-0.024] unit decrease	Affymetrix [NR]	N
rs12935101	16	10121193	A	C	0.260437	8.34786760973e-09	0.00615601640315	0.00106851549541	174	16	10113376	rs837705	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		16p13.2	NR	GRIN2A	""	""	ENSG00000183454			rs837705-A	rs837705	0	837705	intron_variant	0	NR	3E-8	7.52287874528034	""	5.539	z-score decrease	Affymetrix, Illumina [9295118] (imputed)	N
rs12935101	16	10121193	A	C	0.260437	8.34786760973e-09	0.00615601640315	0.00106851549541	174	16	10136889	rs11074547	2019-03-27	30804560	Shrine N	2019-02-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30804560	New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.	FEV1	321,047 European ancestry individuals	79,005 European ancestry individuals	16p13.2	GRIN2A	GRIN2A	""	""	ENSG00000183454			rs11074547-T	rs11074547	0	11074547	intron_variant	0	0.7378	3E-6	5.52287874528034	""	0.0122	[0.0071-0.0173] unit decrease	Affymetrix [19819130] (imputed)	N
rs12935101	16	10121193	A	C	0.260437	8.34786760973e-09	0.00615601640315	0.00106851549541	174	16	10136889	rs11074547	2019-03-27	30804560	Shrine N	2019-02-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30804560	New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.	Lung function (FVC)	321,047 European ancestry individuals	79,005 European ancestry individuals	16p13.2	GRIN2A	GRIN2A	""	""	ENSG00000183454			rs11074547-T	rs11074547	0	11074547	intron_variant	0	0.7378	2E-10	9.69897000433602	""	0.0169	[0.012-0.022] unit decrease	Affymetrix [19819130] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103284865	rs13114738	2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related diseases, mortality and associated endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	4q24	NR	SLC39A8	""	""	ENSG00000138821			rs13114738-?	rs13114738	0	13114738	intron_variant	0	NR	8E-8	7.09691001300806	""		""	Affymetrix [NR]	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103385336	rs531685993	2020-01-28	31676860	Zhao B	2019-11-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/31676860	Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits.	Brain region volumes	19,629 British ancestry individuals		4q24	NR	SLC39A8 - NFKB1	ENSG00000138821	ENSG00000109320	""	32921	37152	rs531685993-?	rs531685993	0	531685993	intergenic_variant	1	NR	4E-15	14.397940008672	(left accumbens area)		""	NR [9227495] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103284865	rs13114738	2017-05-15	27790247	He L	2016-11-03	Front Genet	www.ncbi.nlm.nih.gov/pubmed/27790247	Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.	Age-related disease endophenotypes	9,618 European ancestry individuals	19,796 European ancestry individuals	4q24	NR	SLC39A8	""	""	ENSG00000138821			rs13114738-?	rs13114738	0	13114738	intron_variant	0	NR	1E-10	10	""		""	Affymetrix [NR]	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103228830	rs13105581	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Red blood cell count	408,112 British individuals		4q24	SLC39A8	SLC39A8	""	""	ENSG00000138821			rs13105581-T	rs13105581	0	13105581	intron_variant	0	0.079124	2E-12	11.698970004336	""	0.02915161	[0.021-0.037] unit increase	Affymetrix [93095623] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103228830	rs13105581	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		4q24	SLC39A8	SLC39A8	""	""	ENSG00000138821			rs13105581-T	rs13105581	0	13105581	intron_variant	0	NR	3E-11	10.5228787452803	""	6.629	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103228830	rs13105581	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		4q24	NR	SLC39A8	""	""	ENSG00000138821			rs13105581-T	rs13105581	0	13105581	intron_variant	0	NR	2E-9	8.69897000433602	""	6.003	z-score decrease	Affymetrix, Illumina [9295118] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103385336	rs531685993	2020-01-28	31676860	Zhao B	2019-11-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/31676860	Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits.	Brain region volumes	19,629 British ancestry individuals		4q24	NR	SLC39A8 - NFKB1	ENSG00000138821	ENSG00000109320	""	32921	37152	rs531685993-?	rs531685993	0	531685993	intergenic_variant	1	NR	3E-13	12.5228787452803	(right accumbens area)		""	NR [9227495] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103284865	rs13114738	2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals		4q24	NR	SLC39A8	""	""	ENSG00000138821			rs13114738-C	rs13114738	0	13114738	intron_variant	0	0.917	3E-11	10.5228787452803	(EA)	0.045	unit increase	Affymetrix [at least 7091467] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103228830	rs13105581	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		4q24	SLC39A8	SLC39A8	""	""	ENSG00000138821			rs13105581-T	rs13105581	0	13105581	intron_variant	0	NR	2E-10	9.69897000433602	""	0.036114357	[0.025-0.047] unit decrease	Affymetrix [NR]	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103283117	rs34333163	2021-06-29	33462484	Sinnott-Armstrong N	2021-01-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33462484	Genetics of 35 blood and urine biomarkers in the UK Biobank.	Calcium levels	313,387 European ancestry individuals, 5,576 African ancestry individuals, 6,696 South Asian ancestry individuals		4q24	NR	SLC39A8	""	""	ENSG00000138821			rs34333163-G	rs34333163	0	34333163	intron_variant	0	NR	2E-21	20.698970004336	""	0.0468	[0.037-0.056] unit decrease	Affymetrix [9000000] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103283117	rs34333163	2021-06-29	33462484	Sinnott-Armstrong N	2021-01-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33462484	Genetics of 35 blood and urine biomarkers in the UK Biobank.	Low density lipoprotein cholesterol levels	341,875 European ancestry individuals, 6,003 African ancestry individuals, 7,319 South Asian ancestry individuals		4q24	NR	SLC39A8	""	""	ENSG00000138821			rs34333163-G	rs34333163	0	34333163	intron_variant	0	NR	2E-10	9.69897000433602	""	0.0299	[0.021-0.039] unit decrease	Affymetrix [9000000] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103283117	rs34333163	2021-06-29	33462484	Sinnott-Armstrong N	2021-01-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33462484	Genetics of 35 blood and urine biomarkers in the UK Biobank.	High density lipoprotein cholesterol levels	313,372 European ancestry individuals, 5,573 African ancestry individuals, 6,689 South Asian ancestry individuals		4q24	NR	SLC39A8	""	""	ENSG00000138821			rs34333163-G	rs34333163	0	34333163	intron_variant	0	NR	1E-47	47	""	0.0712	[0.062-0.081] unit decrease	Affymetrix [9000000] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103228830	rs13105581	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		4q24	""	SLC39A8	""	""	ENSG00000138821			rs13105581-?	rs13105581	0	13105581	intron_variant	0	NR	1E-8	8	""		""	NR [6307410] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103283117	rs34333163	2022-08-05	35835914	Watanabe K	2022-07-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35835914	Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.	Insomnia	390,751 European ancestry female cases, 1,018,386 European ancestry female controls		4q24	""	SLC39A8	""	""	ENSG00000138821			rs34333163-A	rs34333163	0	34333163	intron_variant	0	NR	2E-11	10.698970004336	""	0.015	[0.011-0.019] unit decrease	Illumina [10288913] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103283117	rs34333163	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Monocyte percentage of white cells	408,112 British individuals		4q24	SLC39A8	SLC39A8	""	""	ENSG00000138821			rs34333163-G	rs34333163	0	34333163	intron_variant	0	0.070832	2E-11	10.698970004336	""	0.02907804	[0.021-0.038] unit decrease	Affymetrix [93095623] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103283117	rs34333163	2021-06-29	33462484	Sinnott-Armstrong N	2021-01-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33462484	Genetics of 35 blood and urine biomarkers in the UK Biobank.	Serum albumin levels	313,032 European ancestry individuals, 5,573 African ancestry individuals, 6,687 South Asian ancestry individuals		4q24	NR	SLC39A8	""	""	ENSG00000138821			rs34333163-G	rs34333163	0	34333163	intron_variant	0	NR	2E-17	16.698970004336	""	0.0418	[0.032-0.051] unit decrease	Affymetrix [9000000] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103284865	rs13114738	2019-02-14	29507422	Hoffmann TJ	2018-03-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29507422	A large electronic-health-record-based genome-wide study of serum lipids.	High density lipoprotein cholesterol levels	76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals		4q24	NR	SLC39A8	""	""	ENSG00000138821			rs13114738-C	rs13114738	0	13114738	intron_variant	0	NR	3E-12	11.5228787452803	""	0.046	unit increase	Affymetrix [at least 7091467] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103283117	rs34333163	2021-06-29	33462484	Sinnott-Armstrong N	2021-01-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33462484	Genetics of 35 blood and urine biomarkers in the UK Biobank.	Total cholesterol levels	342,508 European ancestry individuals, 6,014 African ancestry individuals, 7,336 South Asian ancestry individuals		4q24	NR	SLC39A8	""	""	ENSG00000138821			rs34333163-G	rs34333163	0	34333163	intron_variant	0	NR	6E-24	23.2218487496164	""	0.0474	[0.038-0.057] unit decrease	Affymetrix [9000000] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103283117	rs34333163	2021-06-29	33462484	Sinnott-Armstrong N	2021-01-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33462484	Genetics of 35 blood and urine biomarkers in the UK Biobank.	Aspartate aminotransferase levels	341,246 European ancestry individuals, 5,982 African ancestry individuals, 7,313 South Asian ancestry individuals		4q24	NR	SLC39A8	""	""	ENSG00000138821			rs34333163-G	rs34333163	0	34333163	intron_variant	0	NR	2E-24	23.698970004336	""	0.0481	[0.039-0.057] unit increase	Affymetrix [9000000] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103283117	rs34333163	2022-08-05	35835914	Watanabe K	2022-07-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35835914	Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.	Insomnia	593,724 European ancestry cases, 1,771,286 European ancestry controls		4q24	""	SLC39A8	""	""	ENSG00000138821			rs34333163-A	rs34333163	0	34333163	intron_variant	0	NR	3E-14	13.5228787452803	""	0.013	[0.0091-0.0169] unit decrease	Illumina [10713943] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103283117	rs34333163	2020-01-28	31676860	Zhao B	2019-11-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/31676860	Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits.	Brain region volumes	19,629 British ancestry individuals		4q24	NR	SLC39A8	""	""	ENSG00000138821			rs34333163-?	rs34333163	0	34333163	intron_variant	0	NR	3E-9	8.52287874528034	(white matter)		""	NR [9227495] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103283117	rs34333163	2021-06-29	33462484	Sinnott-Armstrong N	2021-01-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33462484	Genetics of 35 blood and urine biomarkers in the UK Biobank.	Apolipoprotein A1 levels	311,601 European ancestry individuals, 5,550 African ancestry individuals, 6,682 South Asian ancestry individuals		4q24	NR	SLC39A8	""	""	ENSG00000138821			rs34333163-G	rs34333163	0	34333163	intron_variant	0	NR	2E-38	37.698970004336	""	0.0639	[0.054-0.074] unit decrease	Affymetrix [9000000] (imputed)	N
rs13234629	7	9864109	G	A	0.341948	1.57640468229e-23	-0.00941600323094	0.000941915907038	94	7	9881063	rs6954274	2017-03-17	27089181	Okbay A	2016-04-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27089181	Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.	Subjective well-being	298,420 Korculan (founder/genetic isolate), Split (founder/genetic isolate), Vis (founder/genetic isolate), Erasmus Rucphen (founder/genetic isolate) and other European ancestry individuals		7p21.3	NR	""	""	""	""			rs6954274-A	rs6954274	0	6954274	intergenic_variant	1	0.3765	7E-7	6.15490195998574	""	0.015094717	[0.0091-0.0211] unit decrease	Affymetrix, Illumina, Perlegen [at least 5170349] (imputed)	N
rs13259607	8	71352047	T	C	0.105368	2.42638854538e-08	-0.00888122059086	0.00159205221194	111	8	71352047	rs13259607	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		8q13.3	Intergenic	NCOA2 - RN7SL203P	ENSG00000140396	ENSG00000275128	""	36004	40380	rs13259607-T	rs13259607	0	13259607	intergenic_variant	1	0.0998	4E-9	8.39794000867204	(MTAG)	0.0161	[0.011-0.022] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs13259607	8	71352047	T	C	0.105368	2.42638854538e-08	-0.00888122059086	0.00159205221194	111	8	71352047	rs13259607	2021-06-29	32895543	de la Fuente J	2020-09-07	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/32895543	A general dimension of genetic sharing across diverse cognitive traits inferred from molecular data.	Verbal-numerical reasoning	171,304 British ancestry individuals		8q13.3	""	NCOA2 - RN7SL203P	ENSG00000140396	ENSG00000275128	""	36004	40380	rs13259607-?	rs13259607	0	13259607	intergenic_variant	1	NR	1E-9	9	""		""	NR [7857346] (imputed)	N
rs13259607	8	71352047	T	C	0.105368	2.42638854538e-08	-0.00888122059086	0.00159205221194	111	8	71352047	rs13259607	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		8q13.3	Intergenic	NCOA2 - RN7SL203P	ENSG00000140396	ENSG00000275128	""	36004	40380	rs13259607-T	rs13259607	0	13259607	intergenic_variant	1	0.0952	9E-10	9.04575749056067	(MTAG)	0.0239	[0.016-0.032] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs13259607	8	71352047	T	C	0.105368	2.42638854538e-08	-0.00888122059086	0.00159205221194	111	8	71352047	rs13259607	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		8q13.3	ENSG00000241204	NCOA2 - RN7SL203P	ENSG00000140396	ENSG00000275128	""	36004	40380	rs13259607-T	rs13259607	0	13259607	intergenic_variant	1	NR	1E-9	9	""	0.02984095	[0.02-0.039] unit increase	Affymetrix [NR]	N
rs13259607	8	71352047	T	C	0.105368	2.42638854538e-08	-0.00888122059086	0.00159205221194	111	8	71367006	rs1481045	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		8q13.3	ENSG00000253143	NCOA2 - RN7SL203P	ENSG00000140396	ENSG00000275128	""	50963	25421	rs1481045-T	rs1481045	0	1481045	intergenic_variant	1	NR	7E-10	9.15490195998574	""	0.02374729	[0.016-0.031] unit decrease	Affymetrix [NR]	N
rs1378893	15	51964788	G	A	0.217694	1.91481777939e-08	0.00575598482935	0.00102428293167	169	15	51964210	rs1456297	2018-11-16	30072576	Emilsson V	2018-08-02	Science	www.ncbi.nlm.nih.gov/pubmed/30072576	Co-regulatory networks of human serum proteins link genetics to disease.	Blood protein levels	3,200 European ancestry individuals		15q21.2	SCG3	DMXL2 - SCG3	ENSG00000104093	ENSG00000104112	""	49180	9479	rs1456297-A	rs1456297	0	1456297	regulatory_region_variant	1	0.7996875	4E-58	57.397940008672	(SCG3, 7957_2_3)	0.47128016	[0.41-0.53] unit increase	Illumina [> 1000000] (imputed)	N
rs1378893	15	51964788	G	A	0.217694	1.91481777939e-08	0.00575598482935	0.00102428293167	169	15	51934783	rs2252220	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		15q21.2	Intergenic	DMXL2 - SCG3	ENSG00000104093	ENSG00000104112	""	19753	38906	rs2252220-A	rs2252220	0	2252220	TF_binding_site_variant	1	0.7579	6E-9	8.22184874961636	(MTAG)	0.0155	[0.01-0.021] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs1378893	15	51964788	G	A	0.217694	1.91481777939e-08	0.00575598482935	0.00102428293167	169	15	51964210	rs1456297	2022-02-15	35078996	Gudjonsson A	2022-01-25	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/35078996	A genome-wide association study of serum proteins reveals shared loci with common diseases.	Serum levels of protein SCG3	5,366 Icelandic ancestry individuals		15q21.2	""	DMXL2 - SCG3	ENSG00000104093	ENSG00000104112	""	49180	9479	rs1456297-C	rs1456297	0	1456297	regulatory_region_variant	1	0.1976	2E-111	110.698970004336	""	0.499556	[0.46-0.54] unit decrease	Illumina [7506463] (imputed)	N
rs1378893	15	51964788	G	A	0.217694	1.91481777939e-08	0.00575598482935	0.00102428293167	169	15	51964788	rs1378893	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		15q21.2	""	DMXL2 - SCG3	ENSG00000104093	ENSG00000104112	""	49758	8901	rs1378893-A	rs1378893	0	1378893	regulatory_region_variant	1	0.2379	2E-13	12.698970004336	""	0.00907707	[0.0067-0.0115] unit increase	Illumina [10675380] (imputed)	N
rs1378893	15	51964788	G	A	0.217694	1.91481777939e-08	0.00575598482935	0.00102428293167	169	15	51726258	rs2470167	2022-10-26	36150907	Hatoum AS	2022-07-14	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/36150907	Genome-wide Association Study Shows That Executive Functioning Is Influenced by GABAergic Processes and Is a Neurocognitive Genetic Correlate of Psychiatric Disorders.	Common executive function	427,037 European ancestry individuals		15q21.2	""	GLDN - DMXL2	ENSG00000186417	ENSG00000104093	""	26056	13650	rs2470167-?	rs2470167	0	2470167	intron_variant	1	NR	5E-8	7.30102999566398	""		""	Affymetrix [7391068] (imputed)	N
rs1378893	15	51964788	G	A	0.217694	1.91481777939e-08	0.00575598482935	0.00102428293167	169	15	51985564	rs2606146	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		15q21.2	NR	SCG3	""	""	ENSG00000104112			rs2606146-T	rs2606146	0	2606146	non_coding_transcript_exon_variant	0	NR	3E-8	7.52287874528034	""	5.532	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs1378893	15	51964788	G	A	0.217694	1.91481777939e-08	0.00575598482935	0.00102428293167	169	15	51748146	rs2061425	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		15q21.2	Intergenic	DMXL2	""	""	ENSG00000104093			rs2061425-T	rs2061425	0	2061425	non_coding_transcript_exon_variant	0	0.7561	2E-8	7.69897000433602	(MTAG)	0.0085	[0.0056-0.0114] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs1378893	15	51964788	G	A	0.217694	1.91481777939e-08	0.00575598482935	0.00102428293167	169	15	51741056	rs3751585	2019-02-08	30593698	Hubel C	2018-12-28	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/30593698	Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.	Body fat percentage	70,700 European ancestry female individuals, 85,261 European ancestry male individuals		15q21.2	NR	DMXL2	""	""	ENSG00000104093			rs3751585-?	rs3751585	0	3751585	3_prime_UTR_variant	0	NR	1E-7	7	""	0.13945	[0.088-0.191] unit increase	Affymetrix [7794483] (imputed)	N
rs1378893	15	51964788	G	A	0.217694	1.91481777939e-08	0.00575598482935	0.00102428293167	169	15	51964210	rs1456297	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		15q21.2	SCG3	DMXL2 - SCG3	ENSG00000104093	ENSG00000104112	""	49180	9479	rs1456297-A	rs1456297	0	1456297	regulatory_region_variant	1	NR	1E-8	8	""	0.019475047	[0.013-0.026] unit decrease	Affymetrix [NR]	N
rs1378893	15	51964788	G	A	0.217694	1.91481777939e-08	0.00575598482935	0.00102428293167	169	15	51964865	rs1378892	2018-07-05	29875488	Sun BB	2018-06-06	Nature	www.ncbi.nlm.nih.gov/pubmed/29875488	Genomic atlas of the human plasma proteome.	Blood protein levels	3,301 European ancestry individuals		15q21.2	SCG3	DMXL2 - SCG3	ENSG00000104093	ENSG00000104112	""	49835	8824	rs1378892-C	rs1378892	0	1378892	regulatory_region_variant	1	0.764	1E-68	68	(Secretogranin-3, SCG3.7957.2.3)	0.49	[0.43-0.55] unit increase	Affymetrix [10572788] (imputed)	N
rs1378893	15	51964788	G	A	0.217694	1.91481777939e-08	0.00575598482935	0.00102428293167	169	15	51741056	rs3751585	2019-02-08	30593698	Hubel C	2018-12-28	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/30593698	Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.	Body fat percentage	70,700 European ancestry female individuals, 85,261 European ancestry male individuals		15q21.2	NR	DMXL2	""	""	ENSG00000104093			rs3751585-?	rs3751585	0	3751585	3_prime_UTR_variant	0	NR	4E-6	5.39794000867204	(male)	0.14907	[0.085-0.213] unit increase	Affymetrix [7794483] (imputed)	N
rs1420384	2	171583876	T	G	0.341948	1.13246342039e-95	0.0184238980572	0.000887735609485	38	2	171605495	rs6433243	2019-09-23	31501611	Karlsson T	2019-09-09	Nat Med	www.ncbi.nlm.nih.gov/pubmed/31501611	Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease.	Predicted visceral adipose tissue	325,153 British ancestry individuals		2q31.1	NR	SP5 - EIF2S2P4	ENSG00000204335	ENSG00000128692	""	30907	2820	rs6433243-T	rs6433243	0	6433243	intron_variant	1	0.3517	5E-10	9.30102999566398	""	0.016183173	[0.011-0.021] unit increase	Affymetrix [10549349] (imputed)	N
rs1420384	2	171583876	T	G	0.341948	1.13246342039e-95	0.0184238980572	0.000887735609485	38	2	171629063	rs12472667	2022-11-17	34887591	Graham SE	2021-12-09	Nature	www.ncbi.nlm.nih.gov/pubmed/34887591	The power of genetic diversity in genome-wide association studies of lipids.	Triglyceride levels	1,320,016 European ancestry individuals		2q31.1	""	EIF2S2P4 - Y_RNA	ENSG00000128692	ENSG00000200742	""	19765	10614	rs12472667-G	rs12472667	0	12472667	intron_variant	1	0.361042	3E-8	7.52287874528034	""	0.0100003	[0.0072-0.0128] unit increase	NR [52000000] (imputed)	N
rs1420384	2	171583876	T	G	0.341948	1.13246342039e-95	0.0184238980572	0.000887735609485	38	2	171602460	rs66624589	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability	564,698 European ancestry individuals		2q31.1	Intergenic	SP5 - EIF2S2P4	ENSG00000204335	ENSG00000128692	""	27872	5855	rs66624589-T	rs66624589	0	66624589	intron_variant	1	0.3399	2E-15	14.698970004336	""	0.0164	[0.012-0.021] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs1420384	2	171583876	T	G	0.341948	1.13246342039e-95	0.0184238980572	0.000887735609485	38	2	171631258	rs4668314	2021-10-18	33980691	Martin S	2021-05-12	Diabetes	www.ncbi.nlm.nih.gov/pubmed/33980691	Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease.	Metabolic biomarkers (multivariate analysis)	389,354 European ancestry individuals		2q31.1	""	EIF2S2P4 - Y_RNA	ENSG00000128692	ENSG00000200742	""	21960	8419	rs4668314-G	rs4668314	0	4668314	intron_variant	1	0.39	3E-8	7.52287874528034	""		""	NR [NR] (imputed)	N
rs1420384	2	171583876	T	G	0.341948	1.13246342039e-95	0.0184238980572	0.000887735609485	38	2	171605495	rs6433243	2019-02-06	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Body mass index	approximately 458,000 European ancestry individuals		2q31.1	""	SP5 - EIF2S2P4	ENSG00000204335	ENSG00000128692	""	30907	2820	rs6433243-?	rs6433243	0	6433243	intron_variant	1	NR	6E-8	7.22184874961636	""		""	NR [~ 8900000] (imputed)	N
rs1420384	2	171583876	T	G	0.341948	1.13246342039e-95	0.0184238980572	0.000887735609485	38	2	171629063	rs12472667	2020-07-21	32203549	Richardson TG	2020-03-23	PLoS Med	www.ncbi.nlm.nih.gov/pubmed/32203549	Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.	Triglyceride levels	441,016 European ancestry individuals		2q31.1	ERICH2	EIF2S2P4 - Y_RNA	ENSG00000128692	ENSG00000200742	""	19765	10614	rs12472667-C	rs12472667	0	12472667	intron_variant	1	0.630541	2E-11	10.698970004336	""	0.0138097	[0.0098-0.0179] unit decrease	Affymetrix [NR] (imputed)	N
rs1420384	2	171583876	T	G	0.341948	1.13246342039e-95	0.0184238980572	0.000887735609485	38	2	171629063	rs12472667	2020-07-09	32154731	Ripatti P	2020-03-10	Circ Genom Precis Med	www.ncbi.nlm.nih.gov/pubmed/32154731	Polygenic Hyperlipidemias and Coronary Artery Disease Risk.	Triglyceride levels	324,694 British ancestry individuals		2q31.1	intergenic	EIF2S2P4 - Y_RNA	ENSG00000128692	ENSG00000200742	""	19765	10614	rs12472667-?	rs12472667	0	12472667	intron_variant	1	NR	5E-8	7.30102999566398	""	0.0148	[0.01-0.02] unit increase	Affymetrix [5701386] (imputed)	N
rs1420384	2	171583876	T	G	0.341948	1.13246342039e-95	0.0184238980572	0.000887735609485	38	2	171624415	rs13009323	2021-07-27	34211149	Mills MC	2021-07-01	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/34211149	Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour.	Age at first sexual intercourse	397,338 European ancestry individuals		2q31.1	LOC101926913	EIF2S2P4 - Y_RNA	ENSG00000128692	ENSG00000200742	""	15117	15262	rs13009323-A	rs13009323	0	13009323	intron_variant	1	0.66957	4E-8	7.39794000867204	""	0.0117943	[0.0075-0.0161] unit increase	NR [16516521] (imputed)	N
rs1420384	2	171583876	T	G	0.341948	1.13246342039e-95	0.0184238980572	0.000887735609485	38	2	171635168	rs1420377	2022-11-17	34887591	Graham SE	2021-12-09	Nature	www.ncbi.nlm.nih.gov/pubmed/34887591	The power of genetic diversity in genome-wide association studies of lipids.	Triglyceride levels	40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals		2q31.1	""	EIF2S2P4 - Y_RNA	ENSG00000128692	ENSG00000200742	""	25870	4509	rs1420377-?	rs1420377	0	1420377	non_coding_transcript_exon_variant	1	NR	7E-9	8.15490195998574	""		""	NR [52000000] (imputed)	N
rs1420384	2	171583876	T	G	0.341948	1.13246342039e-95	0.0184238980572	0.000887735609485	38	2	171629063	rs12472667	2020-02-12	31589552	Lind L	2019-10-07	Metab Syndr Relat Disord	www.ncbi.nlm.nih.gov/pubmed/31589552	Genome-Wide Association Study of the Metabolic Syndrome in UK Biobank.	Metabolic syndrome	291,107 European ancestry individuals		2q31.1	ERICH2	EIF2S2P4 - Y_RNA	ENSG00000128692	ENSG00000200742	""	19765	10614	rs12472667-G	rs12472667	0	12472667	intron_variant	1	0.371305	3E-8	7.52287874528034	""	0.0374895	[0.024-0.051] unit increase	Affymetrix [9463307] (imputed)	N
rs1420384	2	171583876	T	G	0.341948	1.13246342039e-95	0.0184238980572	0.000887735609485	38	2	171631258	rs4668314	2021-10-18	33980691	Martin S	2021-05-12	Diabetes	www.ncbi.nlm.nih.gov/pubmed/33980691	Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease.	High density lipoprotein cholesterol levels	392,965 European ancestry individuals		2q31.1	""	EIF2S2P4 - Y_RNA	ENSG00000128692	ENSG00000200742	""	21960	8419	rs4668314-G	rs4668314	0	4668314	intron_variant	1	0.39	9E-7	6.04575749056068	""	0.009	mmol/L decrease	NR [NR] (imputed)	N
rs1420384	2	171583876	T	G	0.341948	1.13246342039e-95	0.0184238980572	0.000887735609485	38	2	171631258	rs4668314	2021-10-18	33980691	Martin S	2021-05-12	Diabetes	www.ncbi.nlm.nih.gov/pubmed/33980691	Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease.	Body fat percentage	442,278 European ancestry individuals		2q31.1	""	EIF2S2P4 - Y_RNA	ENSG00000128692	ENSG00000200742	""	21960	8419	rs4668314-G	rs4668314	0	4668314	intron_variant	1	0.39	4E-10	9.39794000867204	""	0.01	% increase	NR [NR] (imputed)	N
rs1420384	2	171583876	T	G	0.341948	1.13246342039e-95	0.0184238980572	0.000887735609485	38	2	171631258	rs4668314	2021-10-18	33980691	Martin S	2021-05-12	Diabetes	www.ncbi.nlm.nih.gov/pubmed/33980691	Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease.	Sex hormone-binding globulin levels	389,354 European ancestry individuals		2q31.1	""	EIF2S2P4 - Y_RNA	ENSG00000128692	ENSG00000200742	""	21960	8419	rs4668314-G	rs4668314	0	4668314	intron_variant	1	0.39	7E-7	6.15490195998574	""	0.009	nmol/L decrease	NR [NR] (imputed)	N
rs1420384	2	171583876	T	G	0.341948	1.13246342039e-95	0.0184238980572	0.000887735609485	38	2	171631258	rs4668314	2021-10-18	33980691	Martin S	2021-05-12	Diabetes	www.ncbi.nlm.nih.gov/pubmed/33980691	Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease.	Triglycerides	429,011 European ancestry individuals		2q31.1	""	EIF2S2P4 - Y_RNA	ENSG00000128692	ENSG00000200742	""	21960	8419	rs4668314-G	rs4668314	0	4668314	intron_variant	1	0.39	2E-11	10.698970004336	""	0.013	mmol/L increase	NR [NR] (imputed)	N
rs1526903	2	156910857	G	A	0.11829	7.55432691475e-09	0.00684331840383	0.0011843518696	34	2	156916826	rs17244416	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		2q24.1	NR	LINC01876	""	""	ENSG00000226383			rs17244416-C	rs17244416	0	17244416	intron_variant	0	NR	3E-9	8.52287874528034	""	5.909	z-score decrease	Affymetrix, Illumina [9295118] (imputed)	N
rs1526903	2	156910857	G	A	0.11829	7.55432691475e-09	0.00684331840383	0.0011843518696	34	2	156911600	rs72906064	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		2q24.1	NR	LINC01876	""	""	ENSG00000226383			rs72906064-G	rs72906064	0	72906064	intron_variant	0	0.11829	2E-8	7.69897000433602	""	0.054142527	[0.035-0.073] unit increase	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs1526903	2	156910857	G	A	0.11829	7.55432691475e-09	0.00684331840383	0.0011843518696	34	2	156910407	rs72906060	2019-09-04	31374203	Lam M	2019-08-01	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/31374203	Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy)	328,917 individuals with educational attainment measurements, 107,207 individuals with cognitive ability measurements, 77,096 European ancestry schizophrenia cases, 43,456 European ancestry controls		2q24.1	ENSG00000235548	LINC01876	""	""	ENSG00000226383			rs72906060-?	rs72906060	0	72906060	intron_variant	0	NR	3E-8	7.52287874528034	""	0.017926758	[0.012-0.024] unit increase	NR [7306098]	N
rs1526903	2	156910857	G	A	0.11829	7.55432691475e-09	0.00684331840383	0.0011843518696	34	2	156916826	rs17244416	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		2q24.1	""	LINC01876	""	""	ENSG00000226383			rs17244416-?	rs17244416	0	17244416	intron_variant	0	NR	2E-8	7.69897000433602	""		""	NR [6307410] (imputed)	N
rs1526903	2	156910857	G	A	0.11829	7.55432691475e-09	0.00684331840383	0.0011843518696	34	2	156911600	rs72906064	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		2q24.1	Intergenic	LINC01876	""	""	ENSG00000226383			rs72906064-T	rs72906064	0	72906064	intron_variant	0	0.1222	1E-10	10	(MTAG)	0.0224	[0.016-0.029] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs1526903	2	156910857	G	A	0.11829	7.55432691475e-09	0.00684331840383	0.0011843518696	34	2	156916525	rs17244395	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		2q24.1	NR	LINC01876	""	""	ENSG00000226383			rs17244395-?	rs17244395	0	17244395	intron_variant	0	NR	2E-7	6.69897000433602	""	5.179	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs1526903	2	156910857	G	A	0.11829	7.55432691475e-09	0.00684331840383	0.0011843518696	34	2	156911600	rs72906064	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		2q24.1	ENSG00000235548	LINC01876	""	""	ENSG00000226383			rs72906064-T	rs72906064	0	72906064	intron_variant	0	NR	2E-9	8.69897000433602	""	0.028425694	[0.019-0.038] unit decrease	Affymetrix [NR]	N
rs1526903	2	156910857	G	A	0.11829	7.55432691475e-09	0.00684331840383	0.0011843518696	34	2	156911600	rs72906064	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance	257,841 European ancestry individuals		2q24.1	Intergenic	LINC01876	""	""	ENSG00000226383			rs72906064-T	rs72906064	0	72906064	intron_variant	0	0.1222	2E-8	7.69897000433602	""	0.0244	[0.016-0.033] unit decrease	Affymetrix, Illumina [10100000] (imputed)	N
rs1526903	2	156910857	G	A	0.11829	7.55432691475e-09	0.00684331840383	0.0011843518696	34	2	156918668	rs17184889	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		2q24.1	""	LINC01876	""	""	ENSG00000226383			rs17184889-T	rs17184889	0	17184889	intron_variant	0	0.8847	3E-8	7.52287874528034	""	0.00907646	[0.0059-0.0123] unit increase	Illumina [10675380] (imputed)	N
rs1526903	2	156910857	G	A	0.11829	7.55432691475e-09	0.00684331840383	0.0011843518696	34	2	156911600	rs72906064	2021-06-29	32895543	de la Fuente J	2020-09-07	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/32895543	A general dimension of genetic sharing across diverse cognitive traits inferred from molecular data.	Verbal-numerical reasoning	171,304 British ancestry individuals		2q24.1	""	LINC01876	""	""	ENSG00000226383			rs72906064-?	rs72906064	0	72906064	intron_variant	0	NR	7E-10	9.15490195998574	""		""	NR [7857346] (imputed)	N
rs17049167	2	58068825	G	A	0.0934394	7.40479126415e-09	0.00741578726342	0.00128268056011	25	2	58068825	rs17049167	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		2p16.1	NR	ACTG1P22 - VRK2	ENSG00000271615	ENSG00000028116	""	75638	65939	rs17049167-?	rs17049167	0	17049167	intergenic_variant	1	NR	2E-7	6.69897000433602	""	5.161	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs17049167	2	58068825	G	A	0.0934394	7.40479126415e-09	0.00741578726342	0.00128268056011	25	2	58039682	rs72804575	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Smoking status	approximately 458,000 European ancestry individuals		2p16.1	""	ACTG1P22 - VRK2	ENSG00000271615	ENSG00000028116	""	46495	95082	rs72804575-?	rs72804575	0	72804575	intergenic_variant	1	NR	2E-10	9.69897000433602	""		""	NR [~ 8900000] (imputed)	N
rs17049167	2	58068825	G	A	0.0934394	7.40479126415e-09	0.00741578726342	0.00128268056011	25	2	58122650	rs7595529	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		2p16.1	Intergenic	ACTG1P22 - VRK2	ENSG00000271615	ENSG00000028116	""	129463	12114	rs7595529-A	rs7595529	0	7595529	intergenic_variant	1	0.9213	2E-12	11.698970004336	(MTAG)	0.0173	[0.012-0.022] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs17049167	2	58068825	G	A	0.0934394	7.40479126415e-09	0.00741578726342	0.00128268056011	25	2	58122650	rs7595529	2022-04-05	34855049	Pasman JA	2021-12-02	Behav Genet	www.ncbi.nlm.nih.gov/pubmed/34855049	Genetic Risk for Smoking: Disentangling Interplay Between Genes and Socioeconomic Status.	Educational attainment	451,800 European or unknown ancestry individuals		2p16.1	""	ACTG1P22 - VRK2	ENSG00000271615	ENSG00000028116	""	129463	12114	rs7595529-?	rs7595529	0	7595529	intergenic_variant	1	NR	1E-9	9	""		""	NR [1300000]	N
rs17049167	2	58068825	G	A	0.0934394	7.40479126415e-09	0.00741578726342	0.00128268056011	25	2	58172111	rs72808464	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		2p16.1	NR	VRK2	""	""	ENSG00000028116			rs72808464-?	rs72808464	0	72808464	intron_variant	0	NR	4E-6	5.39794000867204	""	4.639	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs17049167	2	58068825	G	A	0.0934394	7.40479126415e-09	0.00741578726342	0.00128268056011	25	2	58076075	rs7600039	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		2p16.1	""	ACTG1P22 - VRK2	ENSG00000271615	ENSG00000028116	""	82888	58689	rs7600039-T	rs7600039	0	7600039	intergenic_variant	1	0.0797	2E-15	14.698970004336	""	0.0154077	[0.012-0.019] unit decrease	Illumina [10675380] (imputed)	N
rs17049167	2	58068825	G	A	0.0934394	7.40479126415e-09	0.00741578726342	0.00128268056011	25	2	58122650	rs7595529	2019-02-06	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Educational attainment (years of education)	approximately 455,000 European ancestry individuals		2p16.1	""	ACTG1P22 - VRK2	ENSG00000271615	ENSG00000028116	""	129463	12114	rs7595529-?	rs7595529	0	7595529	intergenic_variant	1	NR	1E-10	10	""		""	NR [~ 8900000] (imputed)	N
rs17049167	2	58068825	G	A	0.0934394	7.40479126415e-09	0.00741578726342	0.00128268056011	25	2	58002882	rs6754296	2019-02-06	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Body mass index	approximately 458,000 European ancestry individuals		2p16.1	""	ACTG1P22 - NA	ENSG00000271615	""	""	9695		rs6754296-?	rs6754296	0	6754296	intergenic_variant	1	NR	4E-8	7.39794000867204	""		""	NR [~ 8900000] (imputed)	N
rs17049167	2	58068825	G	A	0.0934394	7.40479126415e-09	0.00741578726342	0.00128268056011	25	2	57948003	rs17049085	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance	257,841 European ancestry individuals		2p16.1	Intergenic	EIF2S2P7 - ACTG1P22	ENSG00000271115	ENSG00000271615	""	671532	34560	rs17049085-T	rs17049085	0	17049085	regulatory_region_variant	1	0.8812	3E-9	8.52287874528034	""	0.026	[0.017-0.035] unit increase	Affymetrix, Illumina [10100000] (imputed)	N
rs17049167	2	58068825	G	A	0.0934394	7.40479126415e-09	0.00741578726342	0.00128268056011	25	2	58072605	rs60589532	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		2p16.1	""	ACTG1P22 - VRK2	ENSG00000271615	ENSG00000028116	""	79418	62159	rs60589532-A	rs60589532	0	60589532	intergenic_variant	1	0.9345	3E-9	8.52287874528034	""	0.0168	[0.011-0.022] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs17049167	2	58068825	G	A	0.0934394	7.40479126415e-09	0.00741578726342	0.00128268056011	25	2	58135485	rs17049244	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		2p16.1	Intergenic	VRK2	""	""	ENSG00000028116			rs17049244-T	rs17049244	0	17049244	intron_variant	0	0.9231	6E-10	9.22184874961636	(MTAG)	0.0192	[0.013-0.025] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs17049167	2	58068825	G	A	0.0934394	7.40479126415e-09	0.00741578726342	0.00128268056011	25	2	57959287	rs55873931	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		2p16.1	NR	NA - ACTG1P22	""	ENSG00000271615	""		23276	rs55873931-?	rs55873931	0	55873931	intergenic_variant	1	NR	8E-8	7.09691001300806	""	5.374	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs17049167	2	58068825	G	A	0.0934394	7.40479126415e-09	0.00741578726342	0.00128268056011	25	2	57948003	rs17049085	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		2p16.1	NR	EIF2S2P7 - ACTG1P22	ENSG00000271115	ENSG00000271615	""	671532	34560	rs17049085-T	rs17049085	0	17049085	regulatory_region_variant	1	0.12326	4E-9	8.39794000867204	""	0.056083716	[0.037-0.075] unit increase	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs17049167	2	58068825	G	A	0.0934394	7.40479126415e-09	0.00741578726342	0.00128268056011	25	2	58168339	rs72808453	2021-11-02	34446935	Karlsson Linner R	2021-08-26	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/34446935	Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.	Externalizing behaviour (multivariate analysis)	up to 53,293 European ancestry Attention-deficit/hyperactivity disorder individuals, up to 164,684 European ancestry problematic alcohol use individuals, up to 186,875 European ancestry lifetime cannabis use individuals, up to 357,187 European ancestry individuals measuring  reverse-coded age at first sexual intercourse, up to 336,121 European ancestry individuals measuring number of sexual partners, up to 426,379 European ancestry individuals measuring general risk tolerance, up to 1,251,809  European ancestry individuals measuring lifetime smoking initiation		2p16.1	""	VRK2	""	""	ENSG00000028116			rs72808453-A	rs72808453	0	72808453	intron_variant	0	0.918	4E-8	7.39794000867204	""	0.011	[0.0071-0.0149] unit decrease	NR [NR] (imputed)	N
rs17049167	2	58068825	G	A	0.0934394	7.40479126415e-09	0.00741578726342	0.00128268056011	25	2	58122650	rs7595529	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		2p16.1	Intergenic	ACTG1P22 - VRK2	ENSG00000271615	ENSG00000028116	""	129463	12114	rs7595529-A	rs7595529	0	7595529	intergenic_variant	1	0.926	4E-11	10.397940008672	(MTAG)	0.029	[0.02-0.038] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs17049820	2	59139507	C	T	0.100398	2.4087311976e-08	-0.00680416465014	0.00121944033694	26	2	59139507	rs17049820	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		2p16.1	Intergenic	LINC01122	""	""	ENSG00000233723			rs17049820-T	rs17049820	0	17049820	intron_variant	0	0.884	5E-9	8.30102999566398	(MTAG)	0.012	[0.0081-0.0159] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs17049820	2	59139507	C	T	0.100398	2.4087311976e-08	-0.00680416465014	0.00121944033694	26	2	59139507	rs17049820	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		2p16.1	Intergenic	LINC01122	""	""	ENSG00000233723			rs17049820-T	rs17049820	0	17049820	intron_variant	0	0.8856	6E-9	8.22184874961636	(MTAG)	0.0209	[0.014-0.028] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs17049820	2	59139507	C	T	0.100398	2.4087311976e-08	-0.00680416465014	0.00121944033694	26	2	59145722	rs67593591	2020-04-17	31669095	Zhu Z	2019-10-24	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/31669095	Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank.	Body mass index	457,822 European ancestry individuals		2p16.1	NR	LINC01122	""	""	ENSG00000233723			rs67593591-?	rs67593591	0	67593591	intron_variant	0	NR	3E-10	9.52287874528034	""		""	Affymetrix [~ 8270000] (imputed)	N
rs17049820	2	59139507	C	T	0.100398	2.4087311976e-08	-0.00680416465014	0.00121944033694	26	2	59139507	rs17049820	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		2p16.1	LINC01122	LINC01122	""	""	ENSG00000233723			rs17049820-T	rs17049820	0	17049820	intron_variant	0	NR	5E-8	7.30102999566398	""	0.025509462	[0.016-0.035] unit decrease	Affymetrix [NR]	N
rs1720035	12	122347612	G	T	0.200795	1.7932611838e-08	-0.00609323956436	0.00108211764579	156	12	122382179	rs1667586	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		12q24.31	NR	CFAP251	""	""	ENSG00000158023			rs1667586-?	rs1667586	0	1667586	intron_variant	0	NR	6E-7	6.22184874961636	""	5.006	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs1720035	12	122347612	G	T	0.200795	1.7932611838e-08	-0.00609323956436	0.00108211764579	156	12	122347612	rs1720035	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		12q24.31	Intergenic	PSMD9	""	""	ENSG00000110801			rs1720035-T	rs1720035	0	1720035	intron_variant	0	0.1957	2E-8	7.69897000433602	(MTAG)	0.0162	[0.011-0.022] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs1720035	12	122347612	G	T	0.200795	1.7932611838e-08	-0.00609323956436	0.00108211764579	156	12	122346052	rs895960	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		12q24.31	""	RNU7-170P, PSMD9	""	""	ENSG00000239082, ENSG00000110801			rs895960-A	rs895960	0	895960	non_coding_transcript_exon_variant	0	0.2016	1E-15	15	""	0.0104081	[0.0079-0.013] unit decrease	Illumina [10675380] (imputed)	N
rs1720035	12	122347612	G	T	0.200795	1.7932611838e-08	-0.00609323956436	0.00108211764579	156	12	122346052	rs895960	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		12q24.31	Intergenic	RNU7-170P, PSMD9	""	""	ENSG00000239082, ENSG00000110801			rs895960-A	rs895960	0	895960	non_coding_transcript_exon_variant	0	0.202	5E-8	7.30102999566398	(MTAG)	0.0089	[0.0058-0.012] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs1720035	12	122347612	G	T	0.200795	1.7932611838e-08	-0.00609323956436	0.00108211764579	156	12	122429484	rs1169076	2022-08-04	35710981	Liu H	2022-06-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35710981	Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease.	Estimated glomerular filtration rate (creatinine)	1,205,871 European ancestry individuals, 168,300 East Asian ancestry individuals, 63,553 African ancestry individuals, 23,509 Hispanic or Latin American individuals, 22,103 African American individuals, 21,791 Central Asian or South Asian ancestry individuals, 1,502 Middle Eastern ancestry individuals, 939 other admixed ancestry individuals, 602 Native American ancestry individuals, 150 Asian ancestry individuals, 339 individuals		12q24.31	""	CFAP251	""	""	ENSG00000158023			rs1169076-A	rs1169076	0	1169076	intron_variant	0	0.7013	2E-8	7.69897000433602	""	5.583	z score decrease	Affymetrix, Illumina [12653804] (imputed)	N
rs17404136	1	20861033	G	A	0.114314	9.74628237156e-10	-0.00738820034644	0.00120850370448	2	1	20875459	rs4615814	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		1p36.12	Intergenic	RPS4XP4 - FAM43B	ENSG00000215520	ENSG00000183114	""	22215	3607	rs4615814-T	rs4615814	0	4615814	intergenic_variant	1	0.9083	1E-8	8	(MTAG)	0.0176	[0.012-0.024] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs17404136	1	20861033	G	A	0.114314	9.74628237156e-10	-0.00738820034644	0.00120850370448	2	1	20875459	rs4615814	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		1p36.12	Intergenic	RPS4XP4 - FAM43B	ENSG00000215520	ENSG00000183114	""	22215	3607	rs4615814-T	rs4615814	0	4615814	intergenic_variant	1	0.9041	2E-10	9.69897000433602	(MTAG)	0.0142	[0.0099-0.0185] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs17404136	1	20861033	G	A	0.114314	9.74628237156e-10	-0.00738820034644	0.00120850370448	2	1	20882523	rs6689263	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		1p36.12	""	FAM43B - CDA	ENSG00000183114	ENSG00000158825	""	1010	33056	rs6689263-A	rs6689263	0	6689263	downstream_gene_variant	1	0.8872	1E-10	10	""	0.0106131	[0.0074-0.0139] unit decrease	Illumina [10675380] (imputed)	N
rs17404136	1	20861033	G	A	0.114314	9.74628237156e-10	-0.00738820034644	0.00120850370448	2	1	20882523	rs6689263	2022-04-05	34855049	Pasman JA	2021-12-02	Behav Genet	www.ncbi.nlm.nih.gov/pubmed/34855049	Genetic Risk for Smoking: Disentangling Interplay Between Genes and Socioeconomic Status.	Educational attainment	451,800 European or unknown ancestry individuals		1p36.12	""	FAM43B - CDA	ENSG00000183114	ENSG00000158825	""	1010	33056	rs6689263-?	rs6689263	0	6689263	downstream_gene_variant	1	NR	3E-8	7.52287874528034	""		""	NR [1300000]	N
rs17404136	1	20861033	G	A	0.114314	9.74628237156e-10	-0.00738820034644	0.00120850370448	2	1	20875676	rs74701752	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		1p36.12	Intergenic	RPS4XP4 - FAM43B	ENSG00000215520	ENSG00000183114	""	22432	3390	rs74701752-T	rs74701752	0	74701752	intergenic_variant	1	0.0928	1E-10	10	(MTAG)	0.0182	[0.013-0.024] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs17404136	1	20861033	G	A	0.114314	9.74628237156e-10	-0.00738820034644	0.00120850370448	2	1	20807073	rs75810319	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		1p36.12	Intergenic	LINC01141 - CAMK2N1	ENSG00000236963	ENSG00000162545	""	49346	1811	rs75810319-T	rs75810319	0	75810319	regulatory_region_variant	1	0.1042	3E-10	9.52287874528034	(MTAG)	0.0236	[0.016-0.031] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs17404136	1	20861033	G	A	0.114314	9.74628237156e-10	-0.00738820034644	0.00120850370448	2	1	20871750	rs111235962	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		1p36.12	""	RPS4XP4 - FAM43B	ENSG00000215520	ENSG00000183114	""	18506	7316	rs111235962-T	rs111235962	0	111235962	intergenic_variant	1	0.0962	2E-8	7.69897000433602	""	0.0133	[0.0086-0.018] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs17404136	1	20861033	G	A	0.114314	9.74628237156e-10	-0.00738820034644	0.00120850370448	2	1	20864746	rs113923880	2021-12-14	34260948	Cipriani V	2021-07-12	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/34260948	Beyond factor H: The impact of genetic-risk variants for age-related macular degeneration on circulating factor-H-like 1 and factor-H-related protein concentrations.	Complement factor H-like 1 protein levels	252 European ancestry individuals		1p36.12	""	RPS4XP4 - FAM43B	ENSG00000215520	ENSG00000183114	""	11502	14320	rs113923880-G	rs113923880	0	113923880	intergenic_variant	1	NR	8E-6	5.09691001300806	""	0.22515	[0.13-0.32] unit decrease	Illumina [NR] (imputed)	N
rs17404136	1	20861033	G	A	0.114314	9.74628237156e-10	-0.00738820034644	0.00120850370448	2	1	20882523	rs6689263	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		1p36.12	FAM43B	FAM43B - CDA	ENSG00000183114	ENSG00000158825	""	1010	33056	rs6689263-A	rs6689263	0	6689263	downstream_gene_variant	1	NR	3E-10	9.52287874528034	""	0.028203934	[0.019-0.037] unit decrease	Affymetrix [NR]	N
rs17404136	1	20861033	G	A	0.114314	9.74628237156e-10	-0.00738820034644	0.00120850370448	2	1	20818659	rs10916805	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		1p36.12	CAMK2N1	CAMK2N1 - MUL1	ENSG00000162545	ENSG00000090432	""	5956	7282	rs10916805-C	rs10916805	0	10916805	regulatory_region_variant	1	NR	8E-10	9.09691001300806	""	6.145	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs17404136	1	20861033	G	A	0.114314	9.74628237156e-10	-0.00738820034644	0.00120850370448	2	1	20883608	rs79582714	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		1p36.12	FAM43B	FAM43B - CDA	ENSG00000183114	ENSG00000158825	""	2095	31971	rs79582714-T	rs79582714	0	79582714	intergenic_variant	1	NR	3E-10	9.52287874528034	""	6.32	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4463453	8	118871476	T	C	0.363817	3.17544231056e-09	-0.00569128541822	0.000960998676128	113	8	118881208	rs17450716	2020-04-17	31669095	Zhu Z	2019-10-24	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/31669095	Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank.	Body mass index	457,822 European ancestry individuals		8q24.11	NR	EXT1	""	""	ENSG00000182197			rs17450716-?	rs17450716	0	17450716	intron_variant	0	NR	2E-9	8.69897000433602	""		""	Affymetrix [~ 8270000] (imputed)	N
rs4463453	8	118871476	T	C	0.363817	3.17544231056e-09	-0.00569128541822	0.000960998676128	113	8	118881866	rs10103490	2017-11-30	29059683	Michailidou K	2017-10-23	Nature	www.ncbi.nlm.nih.gov/pubmed/29059683	Association analysis identifies 65 new breast cancer risk loci.	Breast cancer	76,192 European ancestry cases, 63,082 European ancestry controls	46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls	8q24.11	NR	EXT1	""	""	ENSG00000182197			rs10103490-C	rs10103490	0	10103490	intron_variant	0	0.3554	4E-6	5.39794000867204	(EA)	0.0319	[0.018-0.045] unit decrease	Illumina [~ 11800000] (imputed)	N
rs17560772	16	7235901	G	A	0.345924	2.53765854513e-10	0.00607490199419	0.000960508143623	172	16	7253286	rs12325273	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs12325273-G	rs12325273	0	12325273	intron_variant	0	0.335984	4E-8	7.39794000867204	""	0.03641445	[0.023-0.049] unit increase	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs17560772	16	7235901	G	A	0.345924	2.53765854513e-10	0.00607490199419	0.000960508143623	172	16	7229579	rs9934041	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		16p13.3	RBFOX1	RBFOX1	""	""	ENSG00000078328			rs9934041-T	rs9934041	0	9934041	intron_variant	0	NR	9E-10	9.04575749056067	""	6.125	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs17560772	16	7235901	G	A	0.345924	2.53765854513e-10	0.00607490199419	0.000960508143623	172	16	7253286	rs12325273	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance	257,841 European ancestry individuals		16p13.3	Intergenic	RBFOX1	""	""	ENSG00000078328			rs12325273-C	rs12325273	0	12325273	intron_variant	0	0.3369	4E-8	7.39794000867204	""	0.0166	[0.011-0.022] unit decrease	Affymetrix, Illumina [10100000] (imputed)	N
rs17672458	7	54741870	C	T	0.33996	4.28409517879e-08	-0.00536780487521	0.000979754977521	98	7	54711985	rs11772108	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		7p11.2	Intergenic	RNU6-1125P - RPL31P35	ENSG00000200471	ENSG00000232612	""	23161	12066	rs11772108-A	rs11772108	0	11772108	intergenic_variant	1	0.7257	4E-13	12.397940008672	(MTAG)	0.0134	[0.0097-0.0171] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs17672458	7	54741870	C	T	0.33996	4.28409517879e-08	-0.00536780487521	0.000979754977521	98	7	54711985	rs11772108	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		7p11.2	""	RNU6-1125P - RPL31P35	ENSG00000200471	ENSG00000232612	""	23161	12066	rs11772108-A	rs11772108	0	11772108	intergenic_variant	1	0.7214	2E-12	11.698970004336	""	0.00820087	[0.0059-0.0105] unit decrease	Illumina [10675380] (imputed)	N
rs17672458	7	54741870	C	T	0.33996	4.28409517879e-08	-0.00536780487521	0.000979754977521	98	7	54732205	rs76436554	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		7p11.2	Intergenic	RPL31P35 - SEC61G	ENSG00000232612	ENSG00000132432	""	7778	87738	rs76436554-C	rs76436554	0	76436554	TF_binding_site_variant	1	0.2969	1E-8	8	(MTAG)	0.0143	[0.0094-0.0192] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs17672458	7	54741870	C	T	0.33996	4.28409517879e-08	-0.00536780487521	0.000979754977521	98	7	54724043	rs1569266	2019-02-06	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Educational attainment (years of education)	approximately 455,000 European ancestry individuals		7p11.2	""	RNU6-1125P - RPL31P35	ENSG00000200471	ENSG00000232612	""	35219	8	rs1569266-?	rs1569266	0	1569266	intergenic_variant	1	NR	1E-9	9	""		""	NR [~ 8900000] (imputed)	N
rs17672458	7	54741870	C	T	0.33996	4.28409517879e-08	-0.00536780487521	0.000979754977521	98	7	54728834	rs41326245	2022-04-05	34855049	Pasman JA	2021-12-02	Behav Genet	www.ncbi.nlm.nih.gov/pubmed/34855049	Genetic Risk for Smoking: Disentangling Interplay Between Genes and Socioeconomic Status.	Educational attainment	451,800 European or unknown ancestry individuals		7p11.2	""	RPL31P35 - SEC61G	ENSG00000232612	ENSG00000132432	""	4407	91109	rs41326245-?	rs41326245	0	41326245	downstream_gene_variant	1	NR	5E-10	9.30102999566398	""		""	NR [1300000]	N
rs17672458	7	54741870	C	T	0.33996	4.28409517879e-08	-0.00536780487521	0.000979754977521	98	7	54710048	rs1545562	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability	564,698 European ancestry individuals		7p11.2	Intergenic	RNU6-1125P - RPL31P35	ENSG00000200471	ENSG00000232612	""	21224	14003	rs1545562-T	rs1545562	0	1545562	intergenic_variant	1	0.7031	2E-9	8.69897000433602	""	0.0128	[0.0087-0.0169] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs17672458	7	54741870	C	T	0.33996	4.28409517879e-08	-0.00536780487521	0.000979754977521	98	7	54710048	rs1545562	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		7p11.2	Intergenic	RNU6-1125P - RPL31P35	ENSG00000200471	ENSG00000232612	""	21224	14003	rs1545562-T	rs1545562	0	1545562	intergenic_variant	1	0.7031	1E-11	11	(MTAG)	0.0133	[0.0094-0.0172] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs17723514	18	63554245	G	A	0.329026	1.57799849688e-08	-0.00545208714401	0.000964482962776	191	18	63554245	rs17723514	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		18q22.1	NR	CDH7	""	""	ENSG00000081138			rs17723514-?	rs17723514	0	17723514	3_prime_UTR_variant	0	NR	2E-6	5.69897000433602	""	4.796	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs17723514	18	63554245	G	A	0.329026	1.57799849688e-08	-0.00545208714401	0.000964482962776	191	18	63501972	rs72944032	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		18q22.1	Intergenic	CDH7	""	""	ENSG00000081138			rs72944032-A	rs72944032	0	72944032	intron_variant	0	0.2504	1E-13	13	(MTAG)	0.0153	[0.011-0.019] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs17723514	18	63554245	G	A	0.329026	1.57799849688e-08	-0.00545208714401	0.000964482962776	191	18	63501972	rs72944032	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability	564,698 European ancestry individuals		18q22.1	Intergenic	CDH7	""	""	ENSG00000081138			rs72944032-G	rs72944032	0	72944032	intron_variant	0	0.7496	8E-11	10.0969100130081	""	0.0146	[0.01-0.019] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs17723514	18	63554245	G	A	0.329026	1.57799849688e-08	-0.00545208714401	0.000964482962776	191	18	63553042	rs17075438	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		18q22.1	Intergenic	CDH7	""	""	ENSG00000081138			rs17075438-A	rs17075438	0	17075438	3_prime_UTR_variant	0	0.2799	7E-15	14.1549019599857	(MTAG)	0.0143	[0.011-0.018] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs17723514	18	63554245	G	A	0.329026	1.57799849688e-08	-0.00545208714401	0.000964482962776	191	18	63516255	rs72944064	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		18q22.1	""	CDH7	""	""	ENSG00000081138			rs72944064-T	rs72944064	0	72944064	intron_variant	0	0.7437	9E-10	9.04575749056067	""	0.0098	[0.0067-0.0129] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs17723514	18	63554245	G	A	0.329026	1.57799849688e-08	-0.00545208714401	0.000964482962776	191	18	63501972	rs72944032	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		18q22.1	""	CDH7	""	""	ENSG00000081138			rs72944032-A	rs72944032	0	72944032	intron_variant	0	0.2527	1E-12	12	""	0.00855676	[0.0062-0.0109] unit increase	Illumina [10675380] (imputed)	N
rs17723514	18	63554245	G	A	0.329026	1.57799849688e-08	-0.00545208714401	0.000964482962776	191	18	63516255	rs72944064	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		18q22.1	Intergenic	CDH7	""	""	ENSG00000081138			rs72944064-T	rs72944064	0	72944064	intron_variant	0	0.7437	4E-12	11.397940008672	(MTAG)	0.0104	[0.0075-0.0133] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs17723514	18	63554245	G	A	0.329026	1.57799849688e-08	-0.00545208714401	0.000964482962776	191	18	63536017	rs2587410	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Irritable mood	366,726 European ancestry individuals		18q22.1	CDH7	CDH7	""	""	ENSG00000081138			rs2587410-T	rs2587410	0	2587410	intron_variant	0	0.253061	1E-8	8	""	5.72	z score decrease	NR [~ 10847151] (imputed)	N
rs17723514	18	63554245	G	A	0.329026	1.57799849688e-08	-0.00545208714401	0.000964482962776	191	18	63501972	rs72944032	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		18q22.1	Intergenic	CDH7	""	""	ENSG00000081138			rs72944032-A	rs72944032	0	72944032	intron_variant	0	0.2594	3E-10	9.52287874528034	(MTAG)	0.0164	[0.011-0.021] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57409538	rs1783827	2019-07-05	31152163	Wuttke M	2019-05-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/31152163	A catalog of genetic loci associated with kidney function from analyses of a million individuals.	Estimated glomerular filtration rate	567,460 European ancestry individuals, 165,726 East Asian ancestry individuals, 13,842 African American individuals, 13,359 South Asian ancestry individuals, 4,961 Hispanic individuals	216,518 European ancestry individuals, 64,204 non-Hispanic black individuals	11q12.1	MIR130A	MIR130A - YPEL4	ENSG00000208009	ENSG00000166793	""	779	3022	rs1783827-A	rs1783827	0	1783827	intron_variant	1	0.6021	4E-10	9.39794000867204	""	0.002	[0.0014-0.0026] unit decrease	Affymetrix, Illumina [8221591] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57409538	rs1783827	2022-05-26	34272381	Stanzick KJ	2021-07-16	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/34272381	Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals.	Estimated glomerular filtration rate (creatinine)	1,004,040 European ancestry individuals, 165,726 East Asian ancestry individuals, 13,842 African American individuals, 13,359 South Asian ancestry individuals, 4,961 Hispanic individuals, 2 individuals	417,288 European ancestry individuals	11q12.1	""	MIR130A - YPEL4	ENSG00000208009	ENSG00000166793	""	779	3022	rs1783827-A	rs1783827	0	1783827	intron_variant	1	0.587785800820339	3E-12	11.5228787452803	""	0.0017941176	[0.0013-0.0023] unit decrease	NR [13633840] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57470188	rs7479922	2020-11-30	32916098	Verweij N	2020-09-02	Cell Syst	www.ncbi.nlm.nih.gov/pubmed/32916098	The Genetic Makeup of the Electrocardiogram.	Electrocardiogram morphology (amplitude at temporal datapoints)	63,706 European and unknown ancestry individuals		11q12.1	ZDHHC5, MED19, TMX2, TMX2-CTNND1	ZDHHC5 - MED19	ENSG00000156599	ENSG00000156603	""	1534	998	rs7479922-A	rs7479922	0	7479922	intergenic_variant	1	0.447926	2E-9	8.69897000433602	(102 ms)	0.0333604	[0.022-0.044] unit decrease	Affymetrix [10000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57544484	rs17455626	2022-07-25	34077760	Alipanahi B	2021-06-01	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/34077760	Large-scale machine-learning-based phenotyping significantly improves genomic discovery for optic nerve head morphology.	Vertical cup-disc ratio	89,579 European ancestry individuals		11q12.1	""	CTNND1	""	""	ENSG00000198561			rs17455626-T	rs17455626	0	17455626	intron_variant	0	NR	3E-11	10.5228787452803	""	0.0313	[0.021-0.041] unit decrease	Affymetrix [8600000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57470188	rs7479922	2020-11-30	32916098	Verweij N	2020-09-02	Cell Syst	www.ncbi.nlm.nih.gov/pubmed/32916098	The Genetic Makeup of the Electrocardiogram.	Electrocardiogram morphology (amplitude at temporal datapoints)	63,706 European and unknown ancestry individuals		11q12.1	ZDHHC5, MED19, TMX2, TMX2-CTNND1	ZDHHC5 - MED19	ENSG00000156599	ENSG00000156603	""	1534	998	rs7479922-A	rs7479922	0	7479922	intergenic_variant	1	0.447926	2E-8	7.69897000433602	(104 ms)	0.031387	[0.02-0.042] unit decrease	Affymetrix [10000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57409538	rs1783827	2019-07-05	31152163	Wuttke M	2019-05-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/31152163	A catalog of genetic loci associated with kidney function from analyses of a million individuals.	Estimated glomerular filtration rate	567,460 European ancestry individuals	216,518 European ancestry individuals	11q12.1	MIR130A	MIR130A - YPEL4	ENSG00000208009	ENSG00000166793	""	779	3022	rs1783827-A	rs1783827	0	1783827	intron_variant	1	0.5692	2E-9	8.69897000433602	""	0.0021	[0.0013-0.0029] unit decrease	Affymetrix, Illumina [8834748] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57470188	rs7479922	2020-11-30	32916098	Verweij N	2020-09-02	Cell Syst	www.ncbi.nlm.nih.gov/pubmed/32916098	The Genetic Makeup of the Electrocardiogram.	Electrocardiogram morphology (amplitude at temporal datapoints)	63,706 European and unknown ancestry individuals		11q12.1	ZDHHC5, MED19, TMX2, TMX2-CTNND1	ZDHHC5 - MED19	ENSG00000156599	ENSG00000156603	""	1534	998	rs7479922-A	rs7479922	0	7479922	intergenic_variant	1	0.447926	6E-9	8.22184874961636	(140 ms)	0.0338989	[0.023-0.045] unit decrease	Affymetrix [10000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57470188	rs7479922	2020-11-30	32916098	Verweij N	2020-09-02	Cell Syst	www.ncbi.nlm.nih.gov/pubmed/32916098	The Genetic Makeup of the Electrocardiogram.	Electrocardiogram morphology (amplitude at temporal datapoints)	63,706 European and unknown ancestry individuals		11q12.1	ZDHHC5, MED19, TMX2, TMX2-CTNND1	ZDHHC5 - MED19	ENSG00000156599	ENSG00000156603	""	1534	998	rs7479922-A	rs7479922	0	7479922	intergenic_variant	1	0.447926	3E-8	7.52287874528034	(100 ms)	0.031274	[0.02-0.042] unit decrease	Affymetrix [10000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57470188	rs7479922	2020-11-30	32916098	Verweij N	2020-09-02	Cell Syst	www.ncbi.nlm.nih.gov/pubmed/32916098	The Genetic Makeup of the Electrocardiogram.	Electrocardiogram morphology (amplitude at temporal datapoints)	63,706 European and unknown ancestry individuals		11q12.1	ZDHHC5, MED19, TMX2, TMX2-CTNND1	ZDHHC5 - MED19	ENSG00000156599	ENSG00000156603	""	1534	998	rs7479922-A	rs7479922	0	7479922	intergenic_variant	1	0.447926	4E-8	7.39794000867204	(84 ms)	0.0305509	[0.019-0.042] unit decrease	Affymetrix [10000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57470188	rs7479922	2020-11-30	32916098	Verweij N	2020-09-02	Cell Syst	www.ncbi.nlm.nih.gov/pubmed/32916098	The Genetic Makeup of the Electrocardiogram.	Electrocardiogram morphology (amplitude at temporal datapoints)	63,706 European and unknown ancestry individuals		11q12.1	ZDHHC5, MED19, TMX2, TMX2-CTNND1	ZDHHC5 - MED19	ENSG00000156599	ENSG00000156603	""	1534	998	rs7479922-A	rs7479922	0	7479922	intergenic_variant	1	0.447926	6E-10	9.22184874961636	(122 ms)	0.034387	[0.023-0.045] unit decrease	Affymetrix [10000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57479732	rs141274831	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Reticulocyte count	408,112 British individuals		11q12.1	MED19, TMX2, TMX2-CTNND1	MED19	""	""	ENSG00000156603			rs141274831-C	rs141274831	0	141274831	5_prime_UTR_variant	0	0.282451	1E-10	10	""	0.01665921	[0.012-0.022] unit increase	Affymetrix [93095623] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57463500	rs1783978	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		11q12.1	""	ZDHHC5	""	""	ENSG00000156599			rs1783978-T	rs1783978	0	1783978	missense_variant	0	0.4434	2E-11	10.698970004336	(conditional-joint)	0.0095	[0.0068-0.0122] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57557668	rs12274865	2020-01-29	31844048	Hill WD	2019-12-16	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/31844048	Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income.	Household income (MTAG)	505,541 British and unknown ancestry individuals		11q12.1	TMX2-CTNND1, RP11-691N7.6, CTNND1	CTNND1	""	""	ENSG00000198561			rs12274865-T	rs12274865	0	12274865	intron_variant	0	0.4368	1E-9	9	""	0.012366145	[0.0084-0.0164] unit increase	Affymetrix [up to 18485882] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57535966	rs11229119	2022-09-14	35879402	Deak JD	2022-07-25	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35879402	Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci.	Opioid use disorder (MTAG)	15,251 European ancestry cases, 538,935 European ancestry controls, 5,435 African ancestry cases, 79,442 African ancestry controls		11q12.1	""	CTNND1	""	""	ENSG00000198561			rs11229119-?	rs11229119	0	11229119	intron_variant	0	NR	7E-11	10.1549019599857	""	6.5	Z score decrease	Affymetrix, Illumina [NR] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57470188	rs7479922	2022-03-07	34910505	van der Meer D	2021-12-15	Sci Adv	www.ncbi.nlm.nih.gov/pubmed/34910505	The genetic architecture of human cortical folding.	Vertex-wise sulcal depth	33,748 European ancestry individuals		11q12.1	""	ZDHHC5 - MED19	ENSG00000156599	ENSG00000156603	""	1534	998	rs7479922-A	rs7479922	0	7479922	intergenic_variant	1	0.44	8E-9	8.09691001300806	""	5.77	z score increase	Affymetrix [9061022] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57470188	rs7479922	2020-11-30	32916098	Verweij N	2020-09-02	Cell Syst	www.ncbi.nlm.nih.gov/pubmed/32916098	The Genetic Makeup of the Electrocardiogram.	Electrocardiogram morphology (amplitude at temporal datapoints)	63,706 European and unknown ancestry individuals		11q12.1	ZDHHC5, MED19, TMX2, TMX2-CTNND1	ZDHHC5 - MED19	ENSG00000156599	ENSG00000156603	""	1534	998	rs7479922-A	rs7479922	0	7479922	intergenic_variant	1	0.447926	2E-8	7.69897000433602	(144 ms)	0.0316374	[0.021-0.043] unit decrease	Affymetrix [10000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57491372	rs2911727	2021-02-26	33563987	Tyrrell J	2021-02-09	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/33563987	Genetic predictors of participation in optional components of UK Biobank.	Participation in an health questionnaire (not invited vs invited)	336,633 European ancestry cases, 114,464 European ancestry controls		11q12.1	NR	TMX2	""	""	ENSG00000213593			rs2911727-T	rs2911727	0	2911727	intron_variant	0	0.548943	5E-10	9.30102999566398	""	1.006	[1.004, 1.007]	Affymetrix [39302896] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57676139	rs140965698	2022-10-24	36168886	Thareja G	2022-09-28	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/36168886	Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.	Plasma protease C1 inhibitor levels	2,935 Qatari ancestry individuals		11q12.1	""	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	35079	8630	rs140965698-C	rs140965698	1	112181796	intergenic_variant	1	0.428109	1E-28	28	""	0.306579	[0.25-0.36] unit increase	NR [10004359]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57666611	rs592785	2019-05-21	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Height	approximately 458,000 European ancestry individuals		11q12.1	""	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	25551	18158	rs592785-?	rs592785	0	592785	intergenic_variant	1	NR	4E-17	16.397940008672	""		""	NR [~ 8900000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57470188	rs7479922	2020-11-30	32916098	Verweij N	2020-09-02	Cell Syst	www.ncbi.nlm.nih.gov/pubmed/32916098	The Genetic Makeup of the Electrocardiogram.	Electrocardiogram morphology (amplitude at temporal datapoints)	63,706 European and unknown ancestry individuals		11q12.1	ZDHHC5, MED19, TMX2, TMX2-CTNND1	ZDHHC5 - MED19	ENSG00000156599	ENSG00000156603	""	1534	998	rs7479922-A	rs7479922	0	7479922	intergenic_variant	1	0.447926	2E-8	7.69897000433602	(116 ms)	0.0312821	[0.02-0.042] unit decrease	Affymetrix [10000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57470188	rs7479922	2020-11-30	32916098	Verweij N	2020-09-02	Cell Syst	www.ncbi.nlm.nih.gov/pubmed/32916098	The Genetic Makeup of the Electrocardiogram.	Electrocardiogram morphology (amplitude at temporal datapoints)	63,706 European and unknown ancestry individuals		11q12.1	ZDHHC5, MED19, TMX2, TMX2-CTNND1	ZDHHC5 - MED19	ENSG00000156599	ENSG00000156603	""	1534	998	rs7479922-A	rs7479922	0	7479922	intergenic_variant	1	0.447926	1E-8	8	(138 ms)	0.033427	[0.022-0.044] unit decrease	Affymetrix [10000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57470188	rs7479922	2020-11-30	32916098	Verweij N	2020-09-02	Cell Syst	www.ncbi.nlm.nih.gov/pubmed/32916098	The Genetic Makeup of the Electrocardiogram.	Electrocardiogram morphology (amplitude at temporal datapoints)	63,706 European and unknown ancestry individuals		11q12.1	ZDHHC5, MED19, TMX2, TMX2-CTNND1	ZDHHC5 - MED19	ENSG00000156599	ENSG00000156603	""	1534	998	rs7479922-A	rs7479922	0	7479922	intergenic_variant	1	0.447926	3E-8	7.52287874528034	(114 ms)	0.0310807	[0.02-0.042] unit decrease	Affymetrix [10000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57431470	rs1783985	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Heel bone mineral density	approximately 446,000 European ancestry individuals		11q12.1	""	CLP1 - ZDHHC5	ENSG00000172409	ENSG00000156599	""	2133	3749	rs1783985-?	rs1783985	0	1783985	intergenic_variant	1	NR	1E-7	7	""		""	NR [~ 8900000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57470188	rs7479922	2020-11-30	32916098	Verweij N	2020-09-02	Cell Syst	www.ncbi.nlm.nih.gov/pubmed/32916098	The Genetic Makeup of the Electrocardiogram.	Electrocardiogram morphology (amplitude at temporal datapoints)	63,706 European and unknown ancestry individuals		11q12.1	ZDHHC5, MED19, TMX2, TMX2-CTNND1	ZDHHC5 - MED19	ENSG00000156599	ENSG00000156603	""	1534	998	rs7479922-A	rs7479922	0	7479922	intergenic_variant	1	0.447926	5E-8	7.30102999566398	(136 ms)	0.0299631	[0.019-0.041] unit decrease	Affymetrix [10000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57462752	rs1783976	2022-11-23	35164939	van der Meer D	2022-02-11	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35164939	Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology.	Brain morphology (MOSTest)	33,735 white British ancestry individuals		11q12.1	""	ZDHHC5	""	""	ENSG00000156599			rs1783976-?	rs1783976	0	1783976	intron_variant	0	NR	4E-7	6.39794000867204	""		""	NR [9061072] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57446272	rs1624389	2022-08-04	35710981	Liu H	2022-06-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35710981	Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease.	Estimated glomerular filtration rate (creatinine)	1,205,871 European ancestry individuals, 168,300 East Asian ancestry individuals, 63,553 African ancestry individuals, 23,509 Hispanic or Latin American individuals, 22,103 African American individuals, 21,791 Central Asian or South Asian ancestry individuals, 1,502 Middle Eastern ancestry individuals, 939 other admixed ancestry individuals, 602 Native American ancestry individuals, 150 Asian ancestry individuals, 339 individuals		11q12.1	""	ZDHHC5	""	""	ENSG00000156599			rs1624389-G	rs1624389	0	1624389	intron_variant	0	0.5874	6E-13	12.2218487496164	""	7.193	z score decrease	Affymetrix, Illumina [12653804] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57610017	rs644219	2020-04-17	31669095	Zhu Z	2019-10-24	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/31669095	Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank.	Waist circumference adjusted for body mass index	457,690 European ancestry individuals		11q12.1	NR	CTNND1 - OR5BA1P	ENSG00000198561	ENSG00000255303	""	22999	19403	rs644219-?	rs644219	0	644219	regulatory_region_variant	1	NR	3E-8	7.52287874528034	""		""	Affymetrix [~ 8270000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57470188	rs7479922	2020-11-30	32916098	Verweij N	2020-09-02	Cell Syst	www.ncbi.nlm.nih.gov/pubmed/32916098	The Genetic Makeup of the Electrocardiogram.	Electrocardiogram morphology (amplitude at temporal datapoints)	63,706 European and unknown ancestry individuals		11q12.1	ZDHHC5, MED19, TMX2, TMX2-CTNND1	ZDHHC5 - MED19	ENSG00000156599	ENSG00000156603	""	1534	998	rs7479922-A	rs7479922	0	7479922	intergenic_variant	1	0.447926	2E-8	7.69897000433602	(120 ms)	0.032162	[0.021-0.043] unit decrease	Affymetrix [10000000] (imputed)	N
rs1896596	5	91112153	T	C	0.38668	3.84788471875e-08	-0.00520150756496	0.000946125220838	74	5	91101678	rs2913445	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		5q14.3	Intergenic	NA - PCBP2P3	""	ENSG00000248826	""		37826	rs2913445-C	rs2913445	0	2913445	intergenic_variant	1	0.3293	3E-11	10.5228787452803	(MTAG)	0.0126	[0.0089-0.0163] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs1896596	5	91112153	T	C	0.38668	3.84788471875e-08	-0.00520150756496	0.000946125220838	74	5	91104306	rs2913436	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		5q14.3	Intergenic	NA - PCBP2P3	""	ENSG00000248826	""		35198	rs2913436-T	rs2913436	0	2913436	intergenic_variant	1	0.3578	2E-8	7.69897000433602	(MTAG)	0.0096	[0.0063-0.0129] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs1896596	5	91112153	T	C	0.38668	3.84788471875e-08	-0.00520150756496	0.000946125220838	74	5	91101678	rs2913445	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability	564,698 European ancestry individuals		5q14.3	Intergenic	NA - PCBP2P3	""	ENSG00000248826	""		37826	rs2913445-G	rs2913445	0	2913445	intergenic_variant	1	0.6707	6E-9	8.22184874961636	""	0.0121	[0.008-0.0162] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs1896596	5	91112153	T	C	0.38668	3.84788471875e-08	-0.00520150756496	0.000946125220838	74	5	91111787	rs2913411	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		5q14.3	NR	NA - PCBP2P3	""	ENSG00000248826	""		27717	rs2913411-?	rs2913411	0	2913411	intergenic_variant	1	NR	2E-6	5.69897000433602	""	4.748	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82524544	rs2134046	2018-01-12	29186694	Lam M	2017-11-28	Cell Rep	www.ncbi.nlm.nih.gov/pubmed/29186694	Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.	Cognitive ability	107,207 European ancestry individuals		15q25.2	EFTUD1	EFL1	""	""	ENSG00000140598			rs2134046-?	rs2134046	0	2134046	intron_variant	0	NR	2E-8	7.69897000433602	""	5.579	z score decrease	Affymetrix, Illumina [7357080] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82530630	rs1972460	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		15q25.2	EFTUD1	EFL1	""	""	ENSG00000140598			rs1972460-A	rs1972460	0	1972460	intron_variant	0	NR	2E-10	9.69897000433602	""	0.018744726	[0.013-0.025] unit decrease	Affymetrix [NR]	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82521770	rs8025964	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		15q25.2	""	EFL1	""	""	ENSG00000140598			rs8025964-?	rs8025964	0	8025964	intron_variant	0	NR	4E-9	8.39794000867204	""		""	NR [6307410] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82521770	rs8025964	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		15q25.2	NR	EFL1	""	""	ENSG00000140598			rs8025964-A	rs8025964	0	8025964	intron_variant	0	NR	6E-10	9.22184874961636	""	6.196	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs11635618	15	83508931	G	T	0.459245	1.25177498194e-08	-0.00529281810517	0.000929784622198	171	15	82524544	rs2134046	2018-01-12	29186694	Lam M	2017-11-28	Cell Rep	www.ncbi.nlm.nih.gov/pubmed/29186694	Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.	Cognitive ability	107,207 European ancestry individuals		15q25.2	EFTUD1	EFL1	""	""	ENSG00000140598			rs2134046-?	rs2134046	0	2134046	intron_variant	0	NR	2E-8	7.69897000433602	""	5.579	z score decrease	Affymetrix, Illumina [7357080] (imputed)	N
rs11635618	15	83508931	G	T	0.459245	1.25177498194e-08	-0.00529281810517	0.000929784622198	171	15	82530630	rs1972460	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		15q25.2	EFTUD1	EFL1	""	""	ENSG00000140598			rs1972460-A	rs1972460	0	1972460	intron_variant	0	NR	2E-10	9.69897000433602	""	0.018744726	[0.013-0.025] unit decrease	Affymetrix [NR]	N
rs11635618	15	83508931	G	T	0.459245	1.25177498194e-08	-0.00529281810517	0.000929784622198	171	15	82521770	rs8025964	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		15q25.2	""	EFL1	""	""	ENSG00000140598			rs8025964-?	rs8025964	0	8025964	intron_variant	0	NR	4E-9	8.39794000867204	""		""	NR [6307410] (imputed)	N
rs11635618	15	83508931	G	T	0.459245	1.25177498194e-08	-0.00529281810517	0.000929784622198	171	15	82521770	rs8025964	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		15q25.2	NR	EFL1	""	""	ENSG00000140598			rs8025964-A	rs8025964	0	8025964	intron_variant	0	NR	6E-10	9.22184874961636	""	6.196	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs1994871	5	111296973	C	A	0.447316	9.44379483092e-09	-0.00394254266378	0.00068680299345	77	5	111161200	rs10041953	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Hematocrit	350,475 European ancestry individuals, 153,015 East Asian ancestry individuals		5q22.1	""	NREP	""	""	ENSG00000134986			rs10041953-T	rs10041953	0	10041953	intron_variant	0	NR	3E-13	12.5228787452803	""	0.0126	[0.0093-0.0159] unit decrease	Affymetrix, Illumina [20538534] (imputed)	N
rs1994871	5	111296973	C	A	0.447316	9.44379483092e-09	-0.00394254266378	0.00068680299345	77	5	111260051	rs10050950	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		5q22.1	""	NREP, NREP-AS1	""	""	ENSG00000134986, ENSG00000250095			rs10050950-A	rs10050950	0	10050950	intron_variant	0	0.3352	5E-11	10.301029995664	""	0.00729904	[0.0051-0.0095] unit decrease	Illumina [10675380] (imputed)	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106638739	rs2478286	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		13q33.2	""	LINC00343 - RNA5SP38	ENSG00000226620	ENSG00000222682	""	188851	168982	rs2478286-?	rs2478286	0	2478286	intron_variant	1	NR	4E-16	15.397940008672	""		""	NR [6307410] (imputed)	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106635351	rs2252003	2018-01-12	29186694	Lam M	2017-11-28	Cell Rep	www.ncbi.nlm.nih.gov/pubmed/29186694	Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.	Cognitive ability (MTAG)	436,124 European ancestry individuals		13q33.2	SNORA25	""	""	""	""			rs2252003-?	rs2252003	0	2252003	intron_variant	1	NR	3E-11	10.5228787452803	""	6.673	z score decrease	Affymetrix, Illumina, Perlegen [7333576] (imputed)	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106635351	rs2252003	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		13q33.2	Intergenic	""	""	""	""			rs2252003-T	rs2252003	0	2252003	intron_variant	1	0.7436	5E-15	14.301029995664	(MTAG)	0.0205	[0.015-0.026] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106639856	rs2251499	2017-07-18	28530673	Sniekers S	2017-05-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28530673	Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence.	Intelligence	up to 58,799 European ancestry adults, up to 19,509 European ancestry children		13q33.2	LINC00343, LINC00460	LINC00343 - RNA5SP38	ENSG00000226620	ENSG00000222682	""	189968	167865	rs2251499-T	rs2251499	0	2251499	intron_variant	1	0.2567	3E-10	9.52287874528034	""	6.313	z score increase	Affymetrix, Illumina [12104294] (imputed)	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106639856	rs2251499	2018-01-12	29186694	Lam M	2017-11-28	Cell Rep	www.ncbi.nlm.nih.gov/pubmed/29186694	Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.	Cognitive ability	107,207 European ancestry individuals		13q33.2	SNORA25	LINC00343 - RNA5SP38	ENSG00000226620	ENSG00000222682	""	189968	167865	rs2251499-?	rs2251499	0	2251499	intron_variant	1	NR	1E-10	10	""	6.457	z score increase	Affymetrix, Illumina [7357080] (imputed)	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106637457	rs2251732	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		13q33.2	Intergenic	""	""	""	""			rs2251732-T	rs2251732	0	2251732	intron_variant	1	0.2561	2E-11	10.698970004336	(MTAG)	0.0127	[0.009-0.0164] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106635351	rs2252003	2018-01-12	29186694	Lam M	2017-11-28	Cell Rep	www.ncbi.nlm.nih.gov/pubmed/29186694	Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.	Cognitive ability	107,207 European ancestry individuals		13q33.2	SNORA25	""	""	""	""			rs2252003-?	rs2252003	0	2252003	intron_variant	1	NR	2E-10	9.69897000433602	""	6.367	z score decrease	Affymetrix, Illumina [7357080] (imputed)	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106640324	rs2478281	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance	257,841 European ancestry individuals		13q33.2	Intergenic	""	""	""	""			rs2478281-A	rs2478281	0	2478281	intron_variant	1	0.7431	3E-12	11.5228787452803	""	0.0227	[0.016-0.029] unit decrease	Affymetrix, Illumina [10100000] (imputed)	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106640324	rs2478281	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		13q33.2	NR	""	""	""	""			rs2478281-G	rs2478281	0	2478281	intron_variant	1	0.258449	5E-12	11.301029995664	""	0.049703777	[0.036-0.064] unit increase	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106640634	rs2265097	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		13q33.2	SNORA25	""	""	""	""			rs2265097-T	rs2265097	0	2265097	intron_variant	1	NR	3E-12	11.5228787452803	""	0.023376854	[0.017-0.03] unit increase	Affymetrix [NR]	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106638739	rs2478286	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		13q33.2	NR	LINC00343 - RNA5SP38	ENSG00000226620	ENSG00000222682	""	188851	168982	rs2478286-C	rs2478286	0	2478286	intron_variant	1	NR	2E-16	15.698970004336	""	8.246	z-score decrease	Affymetrix, Illumina [9295118] (imputed)	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106639856	rs2251499	2019-09-04	31374203	Lam M	2019-08-01	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/31374203	Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy)	328,917 individuals with educational attainment measurements, 107,207 individuals with cognitive ability measurements, 77,096 European ancestry schizophrenia cases, 43,456 European ancestry controls		13q33.2	SNORA25	LINC00343 - RNA5SP38	ENSG00000226620	ENSG00000222682	""	189968	167865	rs2251499-?	rs2251499	0	2251499	intron_variant	1	NR	6E-9	8.22184874961636	""	0.013049886	[0.0086-0.0175] unit increase	NR [7306098]	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106635505	rs2478295	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		13q33.2	SNORA25	""	""	""	""			rs2478295-C	rs2478295	0	2478295	intron_variant	1	NR	8E-13	12.0969100130081	""	7.17	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106635519	rs2476733	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		13q33.2	Intergenic	""	""	""	""			rs2476733-T	rs2476733	0	2476733	intron_variant	1	0.2579	8E-13	12.0969100130081	(MTAG)	0.0146	[0.011-0.019] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106639856	rs2251499	2019-02-06	29520040	Coleman JRI	2018-03-08	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29520040	Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals.	Extremely high intelligence	1,247 European ancestry cases, 86,493 European ancestry controls		13q33.2	NR	LINC00343 - RNA5SP38	ENSG00000226620	ENSG00000222682	""	189968	167865	rs2251499-T	rs2251499	0	2251499	intron_variant	1	0.25	8E-12	11.0969100130081	""	6.85	NR z-score increase	Illumina [up to 12595966] (imputed)	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106639856	rs2251499	2017-07-18	28530673	Sniekers S	2017-05-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28530673	Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence.	Intelligence	up to 58,799 European ancestry adults, up to 19,509 European ancestry children		13q33.2	LINC00343, LINC00460	LINC00343 - RNA5SP38	ENSG00000226620	ENSG00000222682	""	189968	167865	rs2251499-T	rs2251499	0	2251499	intron_variant	1	0.2567	4E-9	8.39794000867204	(Adults)	5.866	z score increase	Affymetrix, Illumina [12104294] (imputed)	N
rs2251829	13	106637090	C	T	0.257455	8.79916646062e-09	0.00582834895379	0.00101320515116	161	13	106635519	rs2476733	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability	564,698 European ancestry individuals		13q33.2	Intergenic	""	""	""	""			rs2476733-T	rs2476733	0	2476733	intron_variant	1	0.2579	9E-9	8.04575749056068	""	0.0128	[0.0085-0.0171] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103204845	rs233817	2016-02-10	25865494	Chan Y	2015-04-09	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/25865494	Genome-wide Analysis of Body Proportion Classifies Height-Associated Variants by Mechanism of Action and Implicates Genes Important for Skeletal Development.	Sitting height ratio	3,545 African American individuals, 12,965 European ancestry women, 8,625 European ancestry men		4q24	NR	SLC39A8	""	""	ENSG00000138821			rs233817-C	rs233817	0	233817	intron_variant	0	0.712	4E-6	5.39794000867204	(EA)	0.05	[0.028-0.072] unit decrease	Affymetrix, Illumina [up to 10250422] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103190128	rs151401	2021-02-19	33547301	Chen VL	2021-02-05	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/33547301	Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology.	Aspartate aminotransferase levels	389,565 European ancestry individuals	134,182 East Asian ancestry individuals	4q24	SLC39A8	SLC39A8	""	""	ENSG00000138821			rs151401-G	rs151401	0	151401	intron_variant	0	0.23	2E-12	11.698970004336	""	7.07	z-score increase	Affymetrix [4314223] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103211254	rs233811	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		4q24	SLC39A8	SLC39A8	""	""	ENSG00000138821			rs233811-A	rs233811	0	233811	intron_variant	0	NR	1E-9	9	""	6.074	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103138621	rs151412	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		4q24	NR	NA - SLC39A8	""	ENSG00000138821	""		33616	rs151412-T	rs151412	0	151412	regulatory_region_variant	1	NR	8E-9	8.09691001300806	""	5.764	z-score decrease	Affymetrix, Illumina [9295118] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103138628	rs151411	2022-08-05	35835914	Watanabe K	2022-07-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35835914	Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.	Insomnia	390,751 European ancestry female cases, 1,018,386 European ancestry female controls		4q24	""	BANK1 - SLC39A8	ENSG00000153064	ENSG00000138821	""	142659	33609	rs151411-A	rs151411	0	151411	regulatory_region_variant	1	NR	7E-11	10.1549019599857	""	0.009	[0.007-0.011] unit decrease	Illumina [10288913] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103213362	rs173048	2020-04-17	31669095	Zhu Z	2019-10-24	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/31669095	Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank.	Body mass index	457,822 European ancestry individuals		4q24	NR	SLC39A8	""	""	ENSG00000138821			rs173048-?	rs173048	0	173048	intron_variant	0	NR	2E-15	14.698970004336	""		""	Affymetrix [~ 8270000] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103191787	rs151404	2021-08-24	34021172	Christakoudi S	2021-05-21	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/34021172	GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer.	Waist circumference adjusted for body mass index	219,872 British ancestry women		4q24	SLC39A8	SLC39A8	""	""	ENSG00000138821			rs151404-A	rs151404	0	151404	intron_variant	0	NR	1E-8	8	""	0.0193588	[0.013-0.026] unit decrease	Affymetrix [321114] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103191787	rs289139 x rs151404	2020-07-28	32450446	Wang H	2020-04-29	Neurobiol Aging	www.ncbi.nlm.nih.gov/pubmed/32450446	Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease.	Total PHF-tau (SNP x SNP interaction)	1,285 individuals		4q24	NR x NR	No mapped genes x SLC39A8	""	""	""			rs289139-? x rs151404-?	rs289139 x rs151404	0		intron_variant x intron_variant		NR	1E-10	10	""		""	Affymetrix, Illumina [279409] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103138628	rs151411	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		4q24	SLC39A8	BANK1 - SLC39A8	ENSG00000153064	ENSG00000138821	""	142659	33609	rs151411-A	rs151411	0	151411	regulatory_region_variant	1	NR	2E-8	7.69897000433602	""	5.658	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs13129951	4	103374760	A	G	0.0924453	2.02999023638e-11	0.0113601499914	0.00169457109727	59	4	103138628	rs151411	2022-08-05	35835914	Watanabe K	2022-07-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35835914	Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.	Insomnia	593,724 European ancestry cases, 1,771,286 European ancestry controls		4q24	""	BANK1 - SLC39A8	ENSG00000153064	ENSG00000138821	""	142659	33609	rs151411-A	rs151411	0	151411	regulatory_region_variant	1	NR	6E-11	10.2218487496164	""	0.007	[0.005-0.009] unit decrease	Illumina [10713943] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82432715	rs2665103	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		15q25.2	EFTUD1	EFL1	""	""	ENSG00000140598			rs2665103-T	rs2665103	0	2665103	intron_variant	0	NR	4E-10	9.39794000867204	""	0.018218447	[0.013-0.024] unit increase	Affymetrix [NR]	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82432715	rs2665103	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		15q25.2	NR	EFL1	""	""	ENSG00000140598			rs2665103-T	rs2665103	0	2665103	intron_variant	0	NR	4E-9	8.39794000867204	""	5.904	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs287879	6	157143339	G	A	0.28827	6.02684310576e-09	-0.00575281706038	0.000989134454075	91	6	157140077	rs287883	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		6q25.3	NR	ARID1B	""	""	ENSG00000049618			rs287883-A	rs287883	0	287883	intron_variant	0	0.28827	4E-9	8.39794000867204	""	0.040757004	[0.027-0.054] unit decrease	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs287879	6	157143339	G	A	0.28827	6.02684310576e-09	-0.00575281706038	0.000989134454075	91	6	157140077	rs287883	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		6q25.3	NR	ARID1B	""	""	ENSG00000049618			rs287883-?	rs287883	0	287883	intron_variant	0	NR	3E-6	5.52287874528034	""	4.647	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs287879	6	157143339	G	A	0.28827	6.02684310576e-09	-0.00575281706038	0.000989134454075	91	6	157140077	rs287883	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance	257,841 European ancestry individuals		6q25.3	Intergenic	ARID1B	""	""	ENSG00000049618			rs287883-A	rs287883	0	287883	intron_variant	0	0.7071	3E-9	8.52287874528034	""	0.0186	[0.013-0.025] unit decrease	Affymetrix, Illumina [10100000] (imputed)	N
rs287879	6	157143339	G	A	0.28827	6.02684310576e-09	-0.00575281706038	0.000989134454075	91	6	157143339	rs287879	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		6q25.3	Intergenic	ARID1B	""	""	ENSG00000049618			rs287879-A	rs287879	0	287879	intron_variant	0	0.7009	2E-8	7.69897000433602	(MTAG)	0.0141	[0.0092-0.019] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs287879	6	157143339	G	A	0.28827	6.02684310576e-09	-0.00575281706038	0.000989134454075	91	6	157143339	rs287879	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		6q25.3	NR	ARID1B	""	""	ENSG00000049618			rs287879-A	rs287879	0	287879	intron_variant	0	NR	8E-10	9.09691001300806	""	6.136	z-score decrease	Affymetrix, Illumina [9295118] (imputed)	N
rs287879	6	157143339	G	A	0.28827	6.02684310576e-09	-0.00575281706038	0.000989134454075	91	6	157143339	rs287879	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		6q25.3	""	ARID1B	""	""	ENSG00000049618			rs287879-?	rs287879	0	287879	intron_variant	0	NR	2E-9	8.69897000433602	""		""	NR [6307410] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127169897	rs10282411	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		7q32.1	Intergenic	ZNF800 - GCC1	ENSG00000048405	ENSG00000179562	""	97919	50785	rs10282411-T	rs10282411	0	10282411	intergenic_variant	1	0.5585	5E-9	8.30102999566398	(MTAG)	0.0135	[0.009-0.018] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127166870	rs4141409	2022-07-14	35383335	Brouwer RM	2022-04-05	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/35383335	Genetic variants associated with longitudinal changes in brain structure across the lifespan.	Total brain volume change rate	15,100 European ancestry individuals		7q32.1	""	ZNF800 - GCC1	ENSG00000048405	ENSG00000179562	""	94892	53812	rs4141409-T	rs4141409	0	4141409	intergenic_variant	1	0.3694	3E-6	5.52287874528034	""	259.5189	[150-369.04] mm3/year decrease	Affymetrix, Illumina, Perlegen [6200000] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127169897	rs10282411	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance	257,841 European ancestry individuals		7q32.1	Intergenic	ZNF800 - GCC1	ENSG00000048405	ENSG00000179562	""	97919	50785	rs10282411-T	rs10282411	0	10282411	intergenic_variant	1	0.5585	7E-10	9.15490195998574	""	0.0177	[0.012-0.023] unit decrease	Affymetrix, Illumina [10100000] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127158357	rs10273635	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		7q32.1	AC000124.1	ZNF800 - GCC1	ENSG00000048405	ENSG00000179562	""	86379	62325	rs10273635-T	rs10273635	0	10273635	intergenic_variant	1	NR	9E-9	8.04575749056068	""	5.753	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127169897	rs10282411	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		7q32.1	""	ZNF800 - GCC1	ENSG00000048405	ENSG00000179562	""	97919	50785	rs10282411-?	rs10282411	0	10282411	intergenic_variant	1	NR	1E-10	10	""		""	NR [6307410] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127178162	rs4731367	2016-12-01	27015805	Pilling LC	2016-03-23	Aging (Albany NY)	www.ncbi.nlm.nih.gov/pubmed/27015805	Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants.	Parental longevity (mother's age at death)	52,776 middle-aged British individuals		7q32.1	NR	NA - GCC1	""	ENSG00000179562	""		42520	rs4731367-?	rs4731367	0	4731367	intergenic_variant	1	NR	9E-6	5.04575749056068	""	0.023252	[0.013-0.033] unit increase	Affymetrix [9658292] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127169897	rs10282411	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		7q32.1	AC000124.1	ZNF800 - GCC1	ENSG00000048405	ENSG00000179562	""	97919	50785	rs10282411-T	rs10282411	0	10282411	intergenic_variant	1	NR	1E-11	11	""	0.021024052	[0.015-0.027] unit decrease	Affymetrix [NR]	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127169897	rs10282411	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		7q32.1	NR	ZNF800 - GCC1	ENSG00000048405	ENSG00000179562	""	97919	50785	rs10282411-T	rs10282411	0	10282411	intergenic_variant	1	NR	1E-11	11	""	6.797	z-score decrease	Affymetrix, Illumina [9295118] (imputed)	N
rs4255041	7	32496383	G	A	0.333002	1.11393653422e-11	0.00660883315623	0.000973181700455	96	7	32493169	rs1580019	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		7p14.3	NR	PDE1C - SLC25A5P5	ENSG00000154678	ENSG00000226421	""	25426	17956	rs1580019-A	rs1580019	0	1580019	downstream_gene_variant	1	0.333996	3E-9	8.52287874528034	""	0.039441753	[0.026-0.052] unit increase	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs4255041	7	32496383	G	A	0.333002	1.11393653422e-11	0.00660883315623	0.000973181700455	96	7	32493169	rs1580019	2018-01-12	29186694	Lam M	2017-11-28	Cell Rep	www.ncbi.nlm.nih.gov/pubmed/29186694	Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.	Cognitive ability	107,207 European ancestry individuals		7p14.3	ENSG00000226468	PDE1C - SLC25A5P5	ENSG00000154678	ENSG00000226421	""	25426	17956	rs1580019-?	rs1580019	0	1580019	downstream_gene_variant	1	NR	4E-9	8.39794000867204	""	5.875	z score increase	Affymetrix, Illumina [7357080] (imputed)	N
rs4255041	7	32496383	G	A	0.333002	1.11393653422e-11	0.00660883315623	0.000973181700455	96	7	32493169	rs1580019	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		7p14.3	Intergenic	PDE1C - SLC25A5P5	ENSG00000154678	ENSG00000226421	""	25426	17956	rs1580019-A	rs1580019	0	1580019	downstream_gene_variant	1	0.6701	9E-13	12.0457574905607	(MTAG)	0.0174	[0.013-0.022] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs4255041	7	32496383	G	A	0.333002	1.11393653422e-11	0.00660883315623	0.000973181700455	96	7	32493169	rs1580019	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance	257,841 European ancestry individuals		7p14.3	Intergenic	PDE1C - SLC25A5P5	ENSG00000154678	ENSG00000226421	""	25426	17956	rs1580019-A	rs1580019	0	1580019	downstream_gene_variant	1	0.6701	2E-9	8.69897000433602	""	0.0181	[0.012-0.024] unit increase	Affymetrix, Illumina [10100000] (imputed)	N
rs4255041	7	32496383	G	A	0.333002	1.11393653422e-11	0.00660883315623	0.000973181700455	96	7	32496503	rs4460271	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		7p14.3	""	PDE1C - SLC25A5P5	ENSG00000154678	ENSG00000226421	""	28760	14622	rs4460271-T	rs4460271	0	4460271	downstream_gene_variant	1	0.6727	3E-12	11.5228787452803	""	0.00776893	[0.0056-0.01] unit increase	Illumina [10675380] (imputed)	N
rs4255041	7	32496383	G	A	0.333002	1.11393653422e-11	0.00660883315623	0.000973181700455	96	7	32486980	rs1376289	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		7p14.3	NR	PDE1C - SLC25A5P5	ENSG00000154678	ENSG00000226421	""	19237	24145	rs1376289-?	rs1376289	0	1376289	intergenic_variant	1	NR	7E-8	7.15490195998574	""	5.397	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4255041	7	32496383	G	A	0.333002	1.11393653422e-11	0.00660883315623	0.000973181700455	96	7	32493169	rs1580019	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		7p14.3	""	PDE1C - SLC25A5P5	ENSG00000154678	ENSG00000226421	""	25426	17956	rs1580019-?	rs1580019	0	1580019	downstream_gene_variant	1	NR	1E-8	8	""		""	NR [6307410] (imputed)	N
rs4255041	7	32496383	G	A	0.333002	1.11393653422e-11	0.00660883315623	0.000973181700455	96	7	32493169	rs1580019	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		7p14.3	NR	PDE1C - SLC25A5P5	ENSG00000154678	ENSG00000226421	""	25426	17956	rs1580019-A	rs1580019	0	1580019	downstream_gene_variant	1	NR	2E-8	7.69897000433602	""	5.652	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs4255041	7	32496383	G	A	0.333002	1.11393653422e-11	0.00660883315623	0.000973181700455	96	7	32493807	rs6949851	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		7p14.3	Intergenic	PDE1C - SLC25A5P5	ENSG00000154678	ENSG00000226421	""	26064	17318	rs6949851-T	rs6949851	0	6949851	downstream_gene_variant	1	0.6731	2E-10	9.69897000433602	(MTAG)	0.0112	[0.0077-0.0147] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs4255041	7	32496383	G	A	0.333002	1.11393653422e-11	0.00660883315623	0.000973181700455	96	7	32494790	rs11765387	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		7p14.3	""	PDE1C - SLC25A5P5	ENSG00000154678	ENSG00000226421	""	27047	16335	rs11765387-T	rs11765387	0	11765387	intergenic_variant	1	0.6734	9E-9	8.04575749056068	""	0.0086	[0.0057-0.0115] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs4255041	7	32496383	G	A	0.333002	1.11393653422e-11	0.00660883315623	0.000973181700455	96	7	32486980	rs1376289	2019-09-04	31374203	Lam M	2019-08-01	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/31374203	Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy)	328,917 individuals with educational attainment measurements, 107,207 individuals with cognitive ability measurements, 77,096 European ancestry schizophrenia cases, 43,456 European ancestry controls		7p14.3	ENSG00000226468	PDE1C - SLC25A5P5	ENSG00000154678	ENSG00000226421	""	19237	24145	rs1376289-?	rs1376289	0	1376289	intergenic_variant	1	NR	8E-11	10.0969100130081	""	0.013688673	[0.0096-0.0178] unit decrease	NR [7306098]	N
rs4255041	7	32496383	G	A	0.333002	1.11393653422e-11	0.00660883315623	0.000973181700455	96	7	32496435	rs4580942	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		7p14.3	Intergenic	PDE1C - SLC25A5P5	ENSG00000154678	ENSG00000226421	""	28692	14690	rs4580942-A	rs4580942	0	4580942	intergenic_variant	1	0.6766	5E-11	10.301029995664	(MTAG)	0.0092	[0.0065-0.0119] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs4255041	7	32496383	G	A	0.333002	1.11393653422e-11	0.00660883315623	0.000973181700455	96	7	32493807	rs6949851	2019-02-06	29520040	Coleman JRI	2018-03-08	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29520040	Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals.	Extremely high intelligence	1,247 European ancestry cases, 86,493 European ancestry controls		7p14.3	AVL9, LSM5	PDE1C - SLC25A5P5	ENSG00000154678	ENSG00000226421	""	26064	17318	rs6949851-T	rs6949851	0	6949851	downstream_gene_variant	1	0.675	5E-8	7.30102999566398	""	5.45	NR z-score increase	Illumina [up to 12595966] (imputed)	N
rs4291171	7	39269010	G	T	0.351889	5.91744191075e-10	0.00594568028929	0.000960124436717	97	7	39270465	rs28599716	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		7p14.1	NR	POU6F2	""	""	ENSG00000106536			rs28599716-?	rs28599716	0	28599716	intron_variant	0	NR	1E-7	7	""	5.259	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4463453	8	118871476	T	C	0.363817	3.17544231056e-09	-0.00569128541822	0.000960998676128	113	8	118846387	rs4546690	2019-05-21	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Height	approximately 458,000 European ancestry individuals		8q24.11	""	EXT1	""	""	ENSG00000182197			rs4546690-?	rs4546690	0	4546690	intron_variant	0	NR	6E-8	7.22184874961636	""		""	NR [~ 8900000] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127151323	rs1592365	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Feeling worry	372,869 European ancestry individuals		7q32.1	GCC1	ZNF800 - GCC1	ENSG00000048405	ENSG00000179562	""	79345	69359	rs1592365-A	rs1592365	0	1592365	intergenic_variant	1	0.466448	1E-8	8	""	5.664	unit increase	NR [10847151] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127179493	rs11764631	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		7q32.1	GCC1	NA - GCC1	""	ENSG00000179562	""		41189	rs11764631-A	rs11764631	0	11764631	intergenic_variant	1	NR	2E-8	7.69897000433602	""	5.58	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127164958	rs6467136	2012-01-18	22158537	Cho YS	2011-12-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22158537	Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.	Type 2 diabetes	5,999 East Asian ancestry cases, 9,001 East Asian ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 159 Filipino ancestry cases, 1,624 Filipino ancestry controls	18,127 East Asian ancestry cases, 17,746 East Asian ancestry controls	7q32.1	PAX4, GCC1	ZNF800 - GCC1	ENSG00000048405	ENSG00000179562	""	92980	55724	rs6467136-G	rs6467136	0	6467136	intergenic_variant	1	0.79	5E-11	10.301029995664	""	1.11	[1.07–1.14]	Affymetrix, Illumina [2626356] (imputed)	N
rs4551267	7	127175236	T	C	0.454274	1.29998556529e-11	0.00635900556812	0.000939480540473	103	7	127203576	rs6976685	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		7q32.1	NR	NA - GCC1	""	ENSG00000179562	""		17106	rs6976685-?	rs6976685	0	6976685	intergenic_variant	1	NR	5E-8	7.30102999566398	""	5.435	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4572926	4	137449726	G	T	0.327038	4.72701015783e-10	-0.00605184006857	0.000971729021636	61	4	137425467	rs7698266	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		4q28.3	""	""	""	""	""			rs7698266-A	rs7698266	0	7698266	intergenic_variant	1	0.6478	1E-10	10	(conditional-joint)	0.0095	[0.0066-0.0124] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs4572926	4	137449726	G	T	0.327038	4.72701015783e-10	-0.00605184006857	0.000971729021636	61	4	137474783	rs7696257	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Smoking initiation (ever regular vs never regular) (MTAG)	up to 1,359,002 European ancestry individuals		4q28.3	NR	TERF1P3 - LINC02511	ENSG00000249311	ENSG00000248869	""	197292	242291	rs7696257-A	rs7696257	0	7696257	non_coding_transcript_exon_variant	1	0.366	5E-12	11.301029995664	""	0.00778155	[0.0056-0.01] unit increase	NR [9732723] (imputed)	N
rs4572926	4	137449726	G	T	0.327038	4.72701015783e-10	-0.00605184006857	0.000971729021636	61	4	137479869	rs9683947	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		4q28.3	Intergenic	""	""	""	""			rs9683947-A	rs9683947	0	9683947	intergenic_variant	1	0.6945	2E-9	8.69897000433602	(MTAG)	0.015	[0.01-0.02] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs4572926	4	137449726	G	T	0.327038	4.72701015783e-10	-0.00605184006857	0.000971729021636	61	4	137526995	rs10014934	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		4q28.3	Intergenic	TERF1P3 - LINC02511	ENSG00000249311	ENSG00000248869	""	249504	190079	rs10014934-T	rs10014934	0	10014934	intergenic_variant	1	0.6285	1E-15	15	(MTAG)	0.0108	[0.0081-0.0135] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs4572926	4	137449726	G	T	0.327038	4.72701015783e-10	-0.00605184006857	0.000971729021636	61	4	137526995	rs10014934	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		4q28.3	""	TERF1P3 - LINC02511	ENSG00000249311	ENSG00000248869	""	249504	190079	rs10014934-T	rs10014934	0	10014934	intergenic_variant	1	0.6251	3E-17	16.5228787452803	""	0.00912604	[0.007-0.0112] unit increase	Illumina [10675380] (imputed)	N
rs4572926	4	137449726	G	T	0.327038	4.72701015783e-10	-0.00605184006857	0.000971729021636	61	4	137474783	rs7696257	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Smoking initiation (ever regular vs never regular)	up to 1,232,091 European ancestry individuals		4q28.3	NR	TERF1P3 - LINC02511	ENSG00000249311	ENSG00000248869	""	197292	242291	rs7696257-A	rs7696257	0	7696257	non_coding_transcript_exon_variant	1	0.366	7E-9	8.15490195998574	""	0.015331268	[0.01-0.021] unit increase	NR [~ 10000000] (imputed)	N
rs4572926	4	137449726	G	T	0.327038	4.72701015783e-10	-0.00605184006857	0.000971729021636	61	4	137474783	rs7696257	2021-11-02	34446935	Karlsson Linner R	2021-08-26	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/34446935	Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.	Externalizing behaviour (multivariate analysis)	up to 53,293 European ancestry Attention-deficit/hyperactivity disorder individuals, up to 164,684 European ancestry problematic alcohol use individuals, up to 186,875 European ancestry lifetime cannabis use individuals, up to 357,187 European ancestry individuals measuring  reverse-coded age at first sexual intercourse, up to 336,121 European ancestry individuals measuring number of sexual partners, up to 426,379 European ancestry individuals measuring general risk tolerance, up to 1,251,809  European ancestry individuals measuring lifetime smoking initiation		4q28.3	""	TERF1P3 - LINC02511	ENSG00000249311	ENSG00000248869	""	197292	242291	rs7696257-G	rs7696257	0	7696257	non_coding_transcript_exon_variant	1	0.645	2E-9	8.69897000433602	""	0.007	[0.005-0.009] unit decrease	NR [NR] (imputed)	N
rs4572926	4	137449726	G	T	0.327038	4.72701015783e-10	-0.00605184006857	0.000971729021636	61	4	137528075	rs10006237	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		4q28.3	Intergenic	""	""	""	""			rs10006237-T	rs10006237	0	10006237	intergenic_variant	1	0.3688	4E-9	8.39794000867204	(MTAG)	0.0101	[0.0068-0.0134] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs4572926	4	137449726	G	T	0.327038	4.72701015783e-10	-0.00605184006857	0.000971729021636	61	4	137528057	rs59222824	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		4q28.3	NR	""	""	""	""			rs59222824-?	rs59222824	0	59222824	intergenic_variant	1	NR	4E-7	6.39794000867204	""	5.087	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4669647	2	11064348	C	T	0.206759	1.40423432087e-08	0.00611730408069	0.00107834346467	20	2	11073506	rs17365719	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		2p25.1	""	KCNF1 - RPL6P4	ENSG00000162975	ENSG00000226080	""	19155	168762	rs17365719-T	rs17365719	0	17365719	regulatory_region_variant	1	0.1541	8E-10	9.09691001300806	""	0.00890498	[0.0061-0.0117] unit increase	Illumina [10675380] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82521707	rs62012045	2022-02-14	35079123	Chambers T	2022-01-25	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35079123	Genetic common variants associated with cerebellar volume and their overlap with mental disorders: a study on 33,265 individuals from the UK-Biobank.	Total cerebellar volume (excluding Crus I vermis)	33,265 European ancestry individuals		15q25.2	""	EFL1	""	""	ENSG00000140598			rs62012045-A	rs62012045	0	62012045	intron_variant	0	NR	1E-8	8	""	0.0315	[0.021-0.042] unit increase	Affymetrix [6193476] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	83235408	rs17158413	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		15q25.2	NR	CPEB1	""	""	ENSG00000214575			rs17158413-G	rs17158413	0	17158413	intron_variant	0	0.229622	1E-10	10	""	0.048090108	[0.033-0.063] unit decrease	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82546946	rs12439619	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance	257,841 European ancestry individuals		15q25.2	Intergenic	EFL1	""	""	ENSG00000140598			rs12439619-T	rs12439619	0	12439619	intron_variant	0	0.6854	8E-11	10.0969100130081	""	0.0199	[0.014-0.026] unit decrease	Affymetrix, Illumina [10100000] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	83226925	rs17507216	2019-09-04	31374203	Lam M	2019-08-01	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/31374203	Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy)	328,917 individuals with educational attainment measurements, 107,207 individuals with cognitive ability measurements, 77,096 European ancestry schizophrenia cases, 43,456 European ancestry controls		15q25.2	ENSG00000261086, CPEB1	CPEB1	""	""	ENSG00000214575			rs17507216-?	rs17507216	0	17507216	intron_variant	0	NR	4E-10	9.39794000867204	""	0.01446739	[0.0099-0.019] unit increase	NR [7306098]	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	83226925	rs17507216	2017-05-11	27992416	Lane JM	2016-12-19	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27992416	Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits.	Excessive daytime sleepiness	111,648 European ancestry individuals		15q25.2	CPEB1	CPEB1	""	""	ENSG00000214575			rs17507216-A	rs17507216	0	17507216	intron_variant	0	0.232	2E-7	6.69897000433602	""	0.026	[0.016-0.036] unit increase	Affymetrix [up to 73355677] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82426170	rs17354185	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		15q25.2	""	EFL1	""	""	ENSG00000140598			rs17354185-?	rs17354185	0	17354185	intron_variant	0	NR	3E-8	7.52287874528034	""		""	NR [6307410] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	83235408	rs17158413	2021-04-15	33568662	Dashti HS	2021-02-10	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/33568662	Genetic determinants of daytime napping and effects on cardiometabolic health.	Daytime nap	452,633 European ancestry individuals	541,333 European ancestry individuals	15q25.2	CPEB1	CPEB1	""	""	ENSG00000214575			rs17158413-A	rs17158413	0	17158413	intron_variant	0	""	2E-13	12.698970004336	""	0.0074	[0.0054-0.0094] unit increase	Affymetrix [13304133] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82546946	rs12439619	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		15q25.2	NR	EFL1	""	""	ENSG00000140598			rs12439619-T	rs12439619	0	12439619	intron_variant	0	0.307157	1E-10	10	""	0.043976955	[0.031-0.057] unit decrease	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	83221392	rs3850610	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		15q25.2	CPEB1, ENSG00000260836, ENSG00000261086	CPEB1	""	""	ENSG00000214575			rs3850610-A	rs3850610	0	3850610	intron_variant	0	NR	3E-9	8.52287874528034	""	5.931	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82546946	rs12439619	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		15q25.2	EFTUD1	EFL1	""	""	ENSG00000140598			rs12439619-T	rs12439619	0	12439619	intron_variant	0	NR	1E-8	8	""	0.018942412	[0.012-0.025] unit decrease	Affymetrix [NR]	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	83235408	rs17158413	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		15q25.2	""	CPEB1	""	""	ENSG00000214575			rs17158413-?	rs17158413	0	17158413	intron_variant	0	NR	2E-8	7.69897000433602	""		""	NR [6307410] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82436504	rs4778665	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		15q25.2	NR	EFL1	""	""	ENSG00000140598			rs4778665-A	rs4778665	0	4778665	intron_variant	0	NR	4E-9	8.39794000867204	""	5.889	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82540337	rs4778988	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		15q25.2	EFTUD1	EFL1	""	""	ENSG00000140598			rs4778988-T	rs4778988	0	4778988	intron_variant	0	NR	2E-8	7.69897000433602	""	5.629	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39781585	rs1007337	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	CD20 on IgD+ CD38dim B cell	3,657 Sardinian (founder/genetic isolate) ancestry individuals		22q13.1	""	SYNGR1 - TAB1	ENSG00000100321	ENSG00000100324	""	5	14198	rs1007337-T	rs1007337	0	1007337	downstream_gene_variant	1	0.60241	3E-8	7.52287874528034	""	0.1389	[0.09-0.188] unit decrease	Illumina [18238311] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39790191	rs2413590	2019-03-28	30586737	Sabater-Lleal M	2018-11-20	Circulation	www.ncbi.nlm.nih.gov/pubmed/30586737	Genome-Wide Association Trans-Ethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.	vWF levels	42,379 European ancestry individuals, 3,700 African American individuals, 275 Hispanic individuals		22q13.1	PFGFB, SYNGR1, TAB1	SYNGR1 - TAB1	ENSG00000100321	ENSG00000100324	""	8611	5592	rs2413590-?	rs2413590	0	2413590	regulatory_region_variant	1	NR	4E-12	11.397940008672	(EA)		""	Affymetrix, Illumina [10537485] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39790191	rs2413590	2019-03-28	30586737	Sabater-Lleal M	2018-11-20	Circulation	www.ncbi.nlm.nih.gov/pubmed/30586737	Genome-Wide Association Trans-Ethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.	vWF levels	42,379 European ancestry individuals, 3,700 African American individuals, 275 Hispanic individuals		22q13.1	PFGFB, SYNGR1, TAB1	SYNGR1 - TAB1	ENSG00000100321	ENSG00000100324	""	8611	5592	rs2413590-?	rs2413590	0	2413590	regulatory_region_variant	1	NR	2E-12	11.698970004336	""		""	Affymetrix, Illumina [10537485] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39829973	rs5750823	2019-03-28	30586737	Sabater-Lleal M	2018-11-20	Circulation	www.ncbi.nlm.nih.gov/pubmed/30586737	Genome-Wide Association Trans-Ethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.	Factor VIII levels	25,897 European ancestry individuals, 4,500 African American individuals, 773 Asian ancestry individuals, 1,440 Hispanic individuals		22q13.1	RPL3, TAB1, SYNGR1, PDGB	TAB1	""	""	ENSG00000100324			rs5750823-T	rs5750823	0	5750823	intron_variant	0	0.7	2E-6	5.69897000433602	""	0.013	NR unit decrease	Affymetrix, Illumina [13887196] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39829973	rs5750823	2019-02-08	30593698	Hubel C	2018-12-28	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/30593698	Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.	Fat-free mass	70,700 European ancestry female individuals, 85,261 European ancestry male individuals		22q13.1	NR	TAB1	""	""	ENSG00000100324			rs5750823-?	rs5750823	0	5750823	intron_variant	0	NR	6E-9	8.22184874961636	(female)	0.16096	[0.11-0.22] unit increase	Affymetrix [7794483] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39829973	rs5750823	2019-02-08	30593698	Hubel C	2018-12-28	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/30593698	Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.	Fat-free mass	70,700 European ancestry female individuals, 85,261 European ancestry male individuals		22q13.1	NR	TAB1	""	""	ENSG00000100324			rs5750823-?	rs5750823	0	5750823	intron_variant	0	NR	7E-8	7.15490195998574	""	0.13627	[0.087-0.186] unit increase	Affymetrix [7794483] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39829973	rs5750823	2019-03-28	30586737	Sabater-Lleal M	2018-11-20	Circulation	www.ncbi.nlm.nih.gov/pubmed/30586737	Genome-Wide Association Trans-Ethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.	vWF levels	42,379 European ancestry individuals, 3,700 African American individuals, 275 Hispanic individuals		22q13.1	PFGFB, SYNGR1, TAB1	TAB1	""	""	ENSG00000100324			rs5750823-T	rs5750823	0	5750823	intron_variant	0	0.73	3E-11	10.5228787452803	(EA)	0.0188	[0.013-0.024] unit decrease	Affymetrix, Illumina [10537485] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39829973	rs5750823	2019-03-28	30586737	Sabater-Lleal M	2018-11-20	Circulation	www.ncbi.nlm.nih.gov/pubmed/30586737	Genome-Wide Association Trans-Ethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.	vWF levels	42,379 European ancestry individuals, 3,700 African American individuals, 275 Hispanic individuals		22q13.1	RPL3, TAB1, SYNGR1, PDGB	TAB1	""	""	ENSG00000100324			rs5750823-T	rs5750823	0	5750823	intron_variant	0	0.72	6E-14	13.2218487496164	""	0.02	[0.015-0.025] unit decrease	Affymetrix, Illumina [10537485] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39829973	rs5750823	2019-05-21	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Height	approximately 458,000 European ancestry individuals		22q13.1	""	TAB1	""	""	ENSG00000100324			rs5750823-?	rs5750823	0	5750823	intron_variant	0	NR	9E-18	17.0457574905607	""		""	NR [~ 8900000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39829973	rs5750823	2022-07-20	35285134	Temprano-Sagrera G	2022-03-14	J Thromb Haemost	www.ncbi.nlm.nih.gov/pubmed/35285134	Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations.	Ischemic stroke or von Willebrand factor levels (pleiotropy)	60,341 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke cases, 454,450 European, African American, East Asian, South Asian, mixed Asian or Latin American ischemic stroke controls, 46,354 European, African American or Hispanic individuals with measurements		22q13.1	""	TAB1	""	""	ENSG00000100324			rs5750823-?	rs5750823	0	5750823	intron_variant	0	NR	1E-12	12	""		""	NR [NR]	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39829973	rs5750823	2022-07-20	35285134	Temprano-Sagrera G	2022-03-14	J Thromb Haemost	www.ncbi.nlm.nih.gov/pubmed/35285134	Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations.	Venous thromboembolism or von Willebrand factor levels (pleiotropy)	30,234 European or African American VTE cases, 172,122 European or African American VTE controls, 46,354 European, African American or Hispanic individuals with measurements		22q13.1	""	TAB1	""	""	ENSG00000100324			rs5750823-?	rs5750823	0	5750823	intron_variant	0	NR	3E-13	12.5228787452803	""		""	NR [NR]	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39829973	rs5750823	2022-07-20	35285134	Temprano-Sagrera G	2022-03-14	J Thromb Haemost	www.ncbi.nlm.nih.gov/pubmed/35285134	Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations.	Coronary artery disease or von Willebrand factor levels (pleiotropy)	172,122 European, South Asian or East Asian CAD cases, 566,864 European, South Asian or East Asian CAD controls, 46,354 European, African American or Hispanic individuals with measurements		22q13.1	""	TAB1	""	""	ENSG00000100324			rs5750823-?	rs5750823	0	5750823	intron_variant	0	NR	8E-13	12.0969100130081	""		""	NR [NR]	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39834102	rs73167342	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	1037	18915	rs73167342-G	rs73167342	0	73167342	intergenic_variant	1	0.6846	5E-31	30.301029995664	(IgG4 Bisecting_GlcNAc)	0.5006	[0.42-0.59] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39834102	rs73167342	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	1037	18915	rs73167342-G	rs73167342	0	73167342	intergenic_variant	1	0.6853	3E-38	37.5228787452803	(IgG4_G0FN/IgG4_G0F)	0.5559	[0.47-0.64] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39834102	rs73167342	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	1037	18915	rs73167342-C	rs73167342	0	73167342	intergenic_variant	1	0.297217	3E-12	11.5228787452803	""	0.04789623	[0.034-0.061] unit decrease	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39834102	rs73167342	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance	257,841 European ancestry individuals		22q13.1	Intergenic	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	1037	18915	rs73167342-C	rs73167342	0	73167342	intergenic_variant	1	0.261	2E-12	11.698970004336	""	0.0229	[0.016-0.029] unit decrease	Affymetrix, Illumina [10100000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39834102	rs73167342	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		22q13.1	Intergenic	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	1037	18915	rs73167342-C	rs73167342	0	73167342	intergenic_variant	1	0.261	1E-16	16	(MTAG)	0.0217	[0.017-0.027] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	7E-19	18.1549019599857	(IgG1 Bn total)	0.384	[0.3-0.47] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	2E-24	23.698970004336	(IgG1 FBG0n/G0n)	0.4425	[0.36-0.53] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	4E-14	13.397940008672	(IgG1 FBG1n/G1n)	0.3266	[0.24-0.41] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	2E-11	10.698970004336	(IgG1 FBG2n/G2n)	0.293	[0.21-0.38] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	3E-18	17.5228787452803	(IgG1 FBn)	0.3784	[0.29-0.46] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	7E-20	19.1549019599857	(IgG1 FBn/Fn)	0.3937	[0.31-0.48] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	7E-20	19.1549019599857	(IgG1 FBn/Fn total)	0.3934	[0.31-0.48] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	1E-18	18	(IgG1 Fn/Bn total)	0.3787	[0.29-0.46] unit increase	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	6E-16	15.2218487496164	(IgG1 FG0n/G0n)	0.3474	[0.26-0.43] unit increase	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	4E-11	10.397940008672	(IgG2_G2FN(10)/(IgG1_G2FN(10) + IgG2_G2FN(10) +IgG4_G2FN(10))	0.2751	[0.19-0.36] unit increase	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.6964	6E-12	11.2218487496164	(IgG2_G2FN(10)/IgG4_G2FN)	0.2832	[0.2-0.36] unit increase	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.6968	4E-8	7.39794000867204	(IgG2 BG0n total/G0n)	0.2415	[0.16-0.33] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.6968	3E-8	7.52287874528034	(IgG2 FBG0n/G0n)	0.2439	[0.16-0.33] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	3E-8	7.52287874528034	(IgG2_G0FN/IgG2_G0F)	0.2429	[0.16-0.33] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	2E-24	23.698970004336	(IgG1 BG0n total/G0n)	0.4406	[0.36-0.53] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	2E-14	13.698970004336	(IgG1 BG1n total/G1n)	0.3307	[0.25-0.42] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.6973	3E-18	17.5228787452803	(IgG1 Bisecting_GlcNAc)	0.3755	[0.29-0.46] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	7E-11	10.1549019599857	(IgG4_G0Fn)	0.2786	[0.19-0.36] unit increase	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	4E-27	26.397940008672	(IgG4_G1FN/IgG4_G1F)	0.4678	[0.38-0.55] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	3E-19	18.5228787452803	(IgG4_G2FN/IgG4_G2F)	0.3804	[0.3-0.46] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	4E-10	9.39794000867204	(IgG4_G2FNn)	0.2636	[0.18-0.35] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	3E-15	14.5228787452803	(IgG1_G1FN)	0.3418	[0.26-0.43] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	6E-15	14.2218487496164	(IgG1_G1FN/IgG1_G1F)	0.3351	[0.25-0.42] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	1E-14	14	(IgG1_G1FNn)	0.3356	[0.25-0.42] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	7E-8	7.15490195998574	(IgG4_G0F)	0.2285	[0.15-0.31] unit increase	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	6E-12	11.2218487496164	(IgG4_G2FN)	0.2906	[0.21-0.37] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-C	rs5750828	0	5750828	intergenic_variant	1	0.697	7E-26	25.1549019599857	(IgG1_G0FN/IgG1_G0F)	0.4527	[0.37-0.54] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2020-04-17	31669095	Zhu Z	2019-10-24	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/31669095	Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank.	Waist-to-hip ratio adjusted for BMI	457,690 European ancestry individuals		22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-?	rs5750828	0	5750828	intergenic_variant	1	NR	4E-9	8.39794000867204	""		""	Affymetrix [~ 8270000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835083	rs5750828	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Waist-hip ratio	approximately 458,000 European ancestry individuals		22q13.1	""	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2018	17934	rs5750828-?	rs5750828	0	5750828	intergenic_variant	1	NR	3E-8	7.52287874528034	""		""	NR [~ 8900000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835587	rs4821897	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2522	17430	rs4821897-G	rs4821897	0	4821897	regulatory_region_variant	1	0.707128727839644	3E-12	11.5228787452803	(IGP63)	0.2388	[0.17-0.31] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39835587	rs4821897	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	2522	17430	rs4821897-G	rs4821897	0	4821897	regulatory_region_variant	1	0.707166482866044	4E-18	17.397940008672	(IGP67)	0.2976	[0.23-0.36] unit decrease	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39837920	rs5757673	2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals		22q13.1	Intergenic	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	4855	15097	rs5757673-T	rs5757673	0	5757673	intergenic_variant	1	0.878	1E-6	6	(AA)	0.126	NR unit increase	Illumina [NR] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39837920	rs5757673	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		22q13.1	Intergenic	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	4855	15097	rs5757673-T	rs5757673	0	5757673	intergenic_variant	1	0.2759	4E-18	17.397940008672	(MTAG)	0.0174	[0.013-0.021] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39837920	rs5757673	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		22q13.1	Intergenic	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	4855	15097	rs5757673-T	rs5757673	0	5757673	intergenic_variant	1	0.2755	4E-14	13.397940008672	(MTAG)	0.0139	[0.01-0.017] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39837920	rs5757673	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability	564,698 European ancestry individuals		22q13.1	Intergenic	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	4855	15097	rs5757673-T	rs5757673	0	5757673	intergenic_variant	1	0.2759	4E-14	13.397940008672	""	0.0165	[0.012-0.021] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39838018	rs5750829	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	4953	14999	rs5750829-G	rs5750829	0	5750829	downstream_gene_variant	1	0.6816	4E-21	20.397940008672	(IgG2_G1FN(10)/(IgG1_G1FN(10) + IgG2_G1FN(10) +IgG4_G1FN(10))	0.4048	[0.32-0.49] unit increase	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39838018	rs5750829	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	4953	14999	rs5750829-G	rs5750829	0	5750829	downstream_gene_variant	1	0.681	5E-7	6.30102999566398	(IgG2_G0F(10)/IgG4_G0F)	0.2101	[0.13-0.29] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39838018	rs5750829	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	CD45 on B cell	3,112 Sardinian (founder/genetic isolate) ancestry individuals		22q13.1	""	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	4953	14999	rs5750829-G	rs5750829	0	5750829	downstream_gene_variant	1	0.59674	4E-9	8.39794000867204	""	0.1537	[0.1-0.2] unit decrease	Illumina [18030716] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39838018	rs5750829	2022-07-18	35332118	Landini A	2022-03-24	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/35332118	Genetic regulation of post-translational modification of two distinct proteins.	Immunoglobulin N-glycan 10 levels	2,020 Korculan or Shetland Isles (founder/genetic isolate) individuals		22q13.1	""	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	4953	14999	rs5750829-A	rs5750829	0	5750829	downstream_gene_variant	1	0.272	4E-12	11.397940008672	(adjusted)	0.25	[0.18-0.32] unit increase	NR [10700000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39838352	rs4821898	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	5287	14665	rs4821898-T	rs4821898	0	4821898	intergenic_variant	1	0.7209	1E-7	7	(IgG4_G2FN(10)/(IgG1_G2FN(10) + IgG2_G2FN(10) +IgG4_G2FN(10))	0.2197	[0.14-0.3] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39838892	rs5757675	2019-04-12	30846698	Dashti HS	2019-03-07	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/30846698	Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates.	Sleep duration (short sleep)	106,192  European ancestry cases, 305,742 European ancestry controls	47,180  adults, 10,554 children or adolescents	22q13.1	MGAT3, SYNGR1, TAB1	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	5827	14125	rs5757675-G	rs5757675	0	5757675	intergenic_variant	1	NR	3E-9	8.52287874528034	""	1.035	""	NR [14661600] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39840828	rs5750830	2020-04-17	32128391	Klaric L	2020-02-19	Sci Adv	www.ncbi.nlm.nih.gov/pubmed/32128391	Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases.	IgG N-glycosylation phenotypes (multivariate analysis)	8,090 European ancestry individuals	2,388 European ancestry individuals	22q13.1	MGAT3	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	7763	12189	rs5750830-A	rs5750830	0	5750830	intergenic_variant	1	0.74	8E-69	68.0969100130081	""	0.344	[NR] unit decrease	Illumina [up to 741151] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39840828	rs5750830	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	7763	12189	rs5750830-A	rs5750830	0	5750830	intergenic_variant	1	NR	2E-13	12.698970004336	""	7.321	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39840828	rs5750830	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		22q13.1	TAB1	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	7763	12189	rs5750830-A	rs5750830	0	5750830	intergenic_variant	1	NR	6E-10	9.22184874961636	""	0.021063557	[0.014-0.028] unit increase	Affymetrix [NR]	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39840828	rs5750830	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		22q13.1	Intergenic	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	7763	12189	rs5750830-A	rs5750830	0	5750830	intergenic_variant	1	0.7407	3E-8	7.52287874528034	(MTAG)	0.0083	[0.0054-0.0112] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39840828	rs5750830	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		22q13.1	""	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	7763	12189	rs5750830-?	rs5750830	0	5750830	intergenic_variant	1	NR	2E-13	12.698970004336	""		""	NR [6307410] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39843537	rs9306335	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	10472	9480	rs9306335-C	rs9306335	0	9306335	intergenic_variant	1	0.721	1E-27	27	(IgG2_G1FN(10)/IgG4_G1FN)	0.4683	[0.38-0.55] unit increase	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39843537	rs9306335	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	10472	9480	rs9306335-C	rs9306335	0	9306335	intergenic_variant	1	0.7218	3E-19	18.5228787452803	(IgG4_G1FN(10)/(IgG1_G1FN(10) + IgG2_G1FN(10) +IgG4_G1FN(10))	0.3854	[0.3-0.47] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39843537	rs9306335	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	10472	9480	rs9306335-C	rs9306335	0	9306335	intergenic_variant	1	0.7209	1E-8	8	(IgG1_G1FN(10)/IgG4_G1FN)	0.2451	[0.16-0.33] unit increase	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39845547	rs5757681	2022-07-20	35285134	Temprano-Sagrera G	2022-03-14	J Thromb Haemost	www.ncbi.nlm.nih.gov/pubmed/35285134	Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations.	Factor VIII levels or von Willebrand factor levels (pleiotropy)	32,610 European, African American, East Asian, South Asian or Hispanic individuals with factor VIII measurements, 46,354 European, African American or Hispanic individuals with vWF measurements		22q13.1	""	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	12482	7470	rs5757681-?	rs5757681	0	5757681	intergenic_variant	1	NR	4E-15	14.397940008672	""		""	NR [NR]	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39845898	rs1005522	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	12833	7119	rs1005522-A	rs1005522	0	1005522	intergenic_variant	1	0.7434	5E-12	11.301029995664	(IgG1_G2FN/IgG1_G2F)	0.3059	[0.22-0.39] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39845898	rs1005522	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	12833	7119	rs1005522-A	rs1005522	0	1005522	intergenic_variant	1	0.7434	1E-10	10	(IgG2_G0FN(10)/(IgG1_G0FN(10) + IgG2_G0FN(10) +IgG4_G0FN(10))	0.2747	[0.19-0.36] unit increase	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39845898	rs1005522	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	12833	7119	rs1005522-A	rs1005522	0	1005522	intergenic_variant	1	0.7434	3E-12	11.5228787452803	(IgG1 BG2n total/G2n)	0.3108	[0.22-0.4] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39845898	rs1005522	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	12833	7119	rs1005522-A	rs1005522	0	1005522	intergenic_variant	1	0.7434	8E-19	18.0969100130081	(IgG4_G0FN)	0.3874	[0.3-0.47] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39845898	rs1005522	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	12833	7119	rs1005522-A	rs1005522	0	1005522	intergenic_variant	1	0.7434	4E-9	8.39794000867204	(IgG1_G0FN)	0.254	[0.17-0.34] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39845898	rs1005522	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	12833	7119	rs1005522-A	rs1005522	0	1005522	intergenic_variant	1	0.7434	3E-10	9.52287874528034	(IgG1_G0FNn)	0.2729	[0.19-0.36] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39845898	rs1005522	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	12833	7119	rs1005522-A	rs1005522	0	1005522	intergenic_variant	1	0.7434	6E-21	20.2218487496164	(IgG4_G0FNn)	0.4111	[0.33-0.5] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39852921	rs6001600	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268	""	19856	96	rs6001600-T	rs6001600	0	6001600	regulatory_region_variant	1	0.7242	7E-7	6.15490195998574	(IgG2_G0FNn)	0.2175	[0.13-0.3] unit decrease	Affymetrix [up to 18185628] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39858196	rs2413592	2022-07-18	35332118	Landini A	2022-03-24	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/35332118	Genetic regulation of post-translational modification of two distinct proteins.	Immunoglobulin N-glycan 23 levels	2,020 Korculan or Shetland Isles (founder/genetic isolate) individuals		22q13.1	""	MGAT3	""	""	ENSG00000128268			rs2413592-A	rs2413592	0	2413592	intron_variant	0	0.277	6E-13	12.2218487496164	""	0.242	[0.18-0.31] unit decrease	NR [10700000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals		22q13.1	MGAT3	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.926	2E-6	5.69897000433602	(AA)	0.143	NR unit increase	Illumina [NR] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2017-11-03	28878392	Shen X	2017-09-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28878392	Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation.	IgG disialylation phenotypes (multivariate analysis)	1,960 Orcadian (founder/genetic isolate) individuals		22q13.1	SYNGR1, TAB1, MGAT3	MGAT3	""	""	ENSG00000128268			rs909674-A	rs909674	0	909674	intron_variant	0	0.78	4E-14	13.397940008672	""		""	Illumina [NR]	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2017-11-03	28878392	Shen X	2017-09-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28878392	Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation.	IgG sialylation phenotypes (multivariate analysis)	1,960 Orcadian (founder/genetic isolate) individuals		22q13.1	SYNGR1, TAB1, MGAT3	MGAT3	""	""	ENSG00000128268			rs909674-A	rs909674	0	909674	intron_variant	0	0.78	1E-13	13	""		""	Illumina [NR]	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2017-11-02	28878392	Shen X	2017-09-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28878392	Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation.	IgG galactosylation phenotypes (multivariate analysis)	1,960 Orcadian (founder/genetic isolate) individuals		22q13.1	SYNGR1, TAB1, MGAT3	MGAT3	""	""	ENSG00000128268			rs909674-A	rs909674	0	909674	intron_variant	0	0.78	2E-14	13.698970004336	""		""	Illumina [NR]	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2017-11-02	28878392	Shen X	2017-09-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28878392	Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation.	IgG monogalactosylation phenotypes (multivariate analysis)	1,960 Orcadian (founder/genetic isolate) individuals		22q13.1	SYNGR1, TAB1, MGAT3	MGAT3	""	""	ENSG00000128268			rs909674-A	rs909674	0	909674	intron_variant	0	0.78	1E-6	6	""		""	Illumina [NR]	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2017-11-02	28878392	Shen X	2017-09-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28878392	Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation.	IgG fucosylation phenotypes (multivariate analysis)	1,960 Orcadian (founder/genetic isolate) individuals		22q13.1	SYNGR1, TAB1, MGAT3	MGAT3	""	""	ENSG00000128268			rs909674-A	rs909674	0	909674	intron_variant	0	0.78	1E-20	20	""		""	Illumina [NR]	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2017-11-02	28878392	Shen X	2017-09-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28878392	Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation.	IgG digalactosylation phenotypes (multivariate analysis)	1,960 Orcadian (founder/genetic isolate) individuals		22q13.1	SYNGR1, TAB1, MGAT3	MGAT3	""	""	ENSG00000128268			rs909674-A	rs909674	0	909674	intron_variant	0	0.78	3E-13	12.5228787452803	""		""	Illumina [NR]	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2017-11-02	28878392	Shen X	2017-09-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28878392	Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation.	IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis)	1,960 Orcadian (founder/genetic isolate) individuals		22q13.1	SYNGR1, TAB1, MGAT3	MGAT3	""	""	ENSG00000128268			rs909674-A	rs909674	0	909674	intron_variant	0	0.78	4E-10	9.39794000867204	""		""	Illumina [NR]	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2017-11-02	28878392	Shen X	2017-09-06	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28878392	Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation.	IgG N-glycosylation phenotypes (multivariate analysis)	1,960 Orcadian (founder/genetic isolate) individuals		22q13.1	SYNGR1, TAB1, MGAT3	MGAT3	""	""	ENSG00000128268			rs909674-A	rs909674	0	909674	intron_variant	0	0.78	3E-19	18.5228787452803	""		""	Illumina [NR]	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.299323467231387	9E-6	5.04575749056068	(IGP69)	0.151	[0.084-0.218] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.298923976402493	6E-10	9.22184874961636	(IGP68)	0.2094	[0.14-0.28] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.299146275601069	2E-15	14.698970004336	(IGP72)	0.2695	[0.2-0.34] unit decrease	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.299100489968792	2E-6	5.69897000433602	(IGP30)	0.1606	[0.095-0.227] unit decrease	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	NR	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.299013119715176	4E-16	15.397940008672	(IGP70)	0.2754	[0.21-0.34] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.299013119715176	6E-16	15.2218487496164	(IGP71)	0.2737	[0.21-0.34] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.299146468388246	2E-10	9.69897000433602	(IGP62)	0.2148	[0.15-0.28] unit decrease	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.298923567230632	5E-10	9.30102999566398	(IGP22)	0.2099	[0.14-0.28] unit decrease	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.299013119715176	3E-8	7.52287874528034	(IGP64)	0.1872	[0.12-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.299013119715176	3E-13	12.5228787452803	(IGP45)	0.2468	[0.18-0.31] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.299056983073497	3E-9	8.52287874528034	(IGP49)	0.2003	[0.13-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.298878222915738	2E-10	9.69897000433602	(IGP34)	0.2136	[0.15-0.28] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.299013119715176	1E-16	16	(IGP66)	0.281	[0.21-0.35] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.298476014725569	9E-24	23.0457574905607	(IGP39)	0.3388	[0.27-0.4] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.298923567230632	1E-10	10	(IGP5)	0.2178	[0.15-0.28] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.299056983073497	3E-9	8.52287874528034	(IGP9)	0.2011	[0.13-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.299013119715176	1E-24	24	(IGP40)	0.3447	[0.28-0.41] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	1,848 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.29096	3E-8	7.52287874528034	(IgG1G0N)	0.083	[0.054-0.112] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	1,848 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.29096	2E-10	9.69897000433602	(IgG1G1N)	0.0721	[0.050-0.094] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	1,848 European ancestry individuals		22q13.1	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3	""	""	ENSG00000128268			rs909674-C	rs909674	0	909674	intron_variant	0	0.29096	9E-6	5.04575749056068	(IgG1G2N)	0.0651	[0.036-0.094] unit increase	Illumina [~ 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39859169	rs909674	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		22q13.1	MGAT3	MGAT3	""	""	ENSG00000128268			rs909674-A	rs909674	0	909674	intron_variant	0	NR	2E-8	7.69897000433602	""	5.624	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39860130	rs2008174	2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals		22q13.1	MGAT3	MGAT3	""	""	ENSG00000128268			rs2008174-C	rs2008174	0	2008174	intron_variant	0	0.925	3E-6	5.52287874528034	(AA)	0.142	NR unit increase	Illumina [NR] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39860130	rs2008174	2020-11-04	33097823	Pei YF	2020-10-23	Commun Biol	www.ncbi.nlm.nih.gov/pubmed/33097823	The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study.	Appendicular lean mass	450,243 European ancestry individuals		22q13.1	MGAT3	MGAT3	""	""	ENSG00000128268			rs2008174-T	rs2008174	0	2008174	intron_variant	0	0.7408	4E-14	13.397940008672	""	0.0168	[0.012-0.021] unit increase	Affymetrix [18391927] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39860589	rs3959642	2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals		22q13.1	MGAT3	MGAT3	""	""	ENSG00000128268			rs3959642-A	rs3959642	0	3959642	intron_variant	0	0.912	1E-7	7	(AA)	0.149	NR unit increase	Illumina [NR] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39860868	rs7286917	2016-10-14	26634245	Lutz SM	2015-12-03	BMC Genet	www.ncbi.nlm.nih.gov/pubmed/26634245	A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.	Post bronchodilator FEV1	10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals		22q13.1	MGAT3	MGAT3	""	""	ENSG00000128268			rs7286917-A	rs7286917	0	7286917	intron_variant	0	0.898	1E-6	6	(AA)	0.133	NR unit increase	Illumina [NR] (imputed)	N
rs4821897	22	39835587	G	A	0.291252	7.32320790917e-09	-0.0059327893674	0.00102584145699	205	22	39860868	rs7286917	2018-06-01	29535710	Wahl A	2018-02-26	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/29535710	Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.	IgG glycosylation patterns	1,823 European ancestry individuals	1,836 European ancestry individuals	22q13.1	NR	MGAT3	""	""	ENSG00000128268			rs7286917-G	rs7286917	0	7286917	intron_variant	0	0.7161	6E-14	13.2218487496164	(IgG1 FG0n/G0n)	0.3434	[0.25-0.43] unit increase	Affymetrix [up to 18185628] (imputed)	N
rs4840138	6	96359062	C	A	0.130219	1.96464206239e-35	-0.015295292314	0.00123122359801	85	6	96346575	rs117488988	2016-07-23	26198764	Goes FS	2015-07-21	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/26198764	Genome-wide association study of schizophrenia in Ashkenazi Jews.	Schizophrenia	592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls		6q16.1	NR	NA - KRT18P50	""	ENSG00000219941	""		92408	rs117488988-A	rs117488988	0	117488988	intergenic_variant	1	NR	5E-6	5.30102999566398	""	1.08	[NR]	Illumina [7158791] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153797015	rs112780312	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		1q21.3	GATAD2B	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs112780312-A	rs112780312	0	112780312	intron_variant	0	NR	1E-8	8	""	5.736	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153823918	rs72694234	2021-12-15	34560273	Shadrin AA	2021-09-21	Neuroimage	www.ncbi.nlm.nih.gov/pubmed/34560273	Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.	Cortical surface area	35,657 White British ancestry individuals		1q21.3	NR	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs72694234-G	rs72694234	0	72694234	intron_variant	0	0.2966	1E-17	17	""		""	NR [9056863] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153822673	rs4612664	2022-03-07	34910505	van der Meer D	2021-12-15	Sci Adv	www.ncbi.nlm.nih.gov/pubmed/34910505	The genetic architecture of human cortical folding.	Vertex-wise sulcal depth	33,748 European ancestry individuals		1q21.3	""	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs4612664-C	rs4612664	0	4612664	intron_variant	0	0.29	3E-25	24.5228787452803	""	10.37	z score increase	Affymetrix [9061022] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153858720	rs7537691	2019-02-01	30573740	Yap CX	2018-12-20	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/30573740	Dissection of genetic variation and evidence for pleiotropy in male pattern baldness.	Male-pattern baldness	205,327 European ancestry males		1q21.3	NR	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs7537691-T	rs7537691	0	7537691	intron_variant	0	0.300041	2E-11	10.698970004336	""	0.0223196	[0.016-0.029] unit decrease	NR [19129689] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153921483	rs199747428	2021-07-27	34211149	Mills MC	2021-07-01	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/34211149	Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour.	Age at first birth	542,901 European ancestry individuals		1q21.3	CRTC2	CRTC2	""	""	ENSG00000160741			rs199747428-A	rs199747428	0	199747428	intron_variant	0	0.3023	4E-14	13.397940008672	""	0.0804	[0.06-0.101] unit decrease	NR [9744772] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153948705	rs11264763	2022-05-10	35446358	He W	2022-04-21	JAMA Ophthalmol	www.ncbi.nlm.nih.gov/pubmed/35446358	Association of Novel Loci With Keratoconus Susceptibility in a Multitrait Genome-Wide Association Study of the UK Biobank Database and Canadian Longitudinal Study on Aging.	Central corneal thickness (MTAG)	17,803 European ancestry individuals		1q21.3	""	JTB	""	""	ENSG00000143543			rs11264763-T	rs11264763	0	11264763	intron_variant	0	0.291	2E-9	8.69897000433602	""	1.55568	[1.05-2.06] unit decrease	NR [NR] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153900490	rs12406003	2022-05-10	35446358	He W	2022-04-21	JAMA Ophthalmol	www.ncbi.nlm.nih.gov/pubmed/35446358	Association of Novel Loci With Keratoconus Susceptibility in a Multitrait Genome-Wide Association Study of the UK Biobank Database and Canadian Longitudinal Study on Aging.	Corneal resistance factor (MTAG)	123,734 European ancestry individuals		1q21.3	""	GATAD2B - DENND4B	ENSG00000143614	ENSG00000198837	""	4654	1487	rs12406003-A	rs12406003	0	12406003	intron_variant	1	0.3001	7E-10	9.15490195998574	""	0.02631	[0.018-0.035] unit decrease	NR [NR] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153926078	rs11264680	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		1q21.3	NR	CRTC2	""	""	ENSG00000160741			rs11264680-?	rs11264680	0	11264680	missense_variant	0	NR	3E-7	6.52287874528034	""	5.149	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153920286	rs8450	2022-09-21	36071172	Wang Z	2022-09-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/36071172	Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention.	Sedentary behavior at work	372,609 European ancestry individuals		1q21.3	""	CRTC2	""	""	ENSG00000160741			rs8450-A	rs8450	0	8450	3_prime_UTR_variant	0	0.305	2E-10	9.69897000433602	""	0.032	[0.022-0.042] unit decrease	Affymetrix, Illumina [21968520] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153797015	rs112780312	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		1q21.3	""	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs112780312-?	rs112780312	0	112780312	intron_variant	0	NR	2E-8	7.69897000433602	""		""	NR [6307410] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153943800	rs6666703	2020-10-23	32665545	van der Meer D	2020-07-14	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/32665545	Understanding the genetic determinants of the brain with MOSTest.	Cortical thickness (MOSTest)	26,502 European ancestry individuals		1q21.3	PRDM16	CREB3L4	""	""	ENSG00000143578			rs6666703-?	rs6666703	0	6666703	intron_variant	0	""	4E-8	7.39794000867204	""		""	NR [7428630] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153927052	rs10908557	2018-08-06	27798627	Barban N	2016-10-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27798627	Genome-wide analysis identifies 12 loci influencing human reproductive behavior.	Age at first birth	189,656 European ancestry women	""	1q21.3	CRTC2, CREB3L4, GATAD2B, SLC39A1, DENND4B	CRTC2	""	""	ENSG00000160741			rs10908557-C	rs10908557	0	10908557	intron_variant	0	0.695	5E-6	5.30102999566398	""	0.076	NR unit increase	Illumina [2400000] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153798128	rs4391701	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		1q21.3	Intergenic	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs4391701-T	rs4391701	0	4391701	intron_variant	0	0.312	8E-18	17.0969100130081	(MTAG)	0.0153	[0.012-0.019] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153797015	rs112780312	2019-02-06	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Balding type 1	approximately 208,000 European ancestry individuals		1q21.3	""	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs112780312-?	rs112780312	0	112780312	intron_variant	0	NR	5E-9	8.30102999566398	""		""	NR [~ 8900000] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153920564	rs10559	2022-09-27	35396580	Trubetskoy V	2022-04-08	Nature	www.ncbi.nlm.nih.gov/pubmed/35396580	Mapping genomic loci implicates genes and synaptic biology in schizophrenia.	Schizophrenia	53,386 European ancestry cases, 77,258 European ancestry controls, 14,004 East Asian ancestry cases, 16,757 East Asian ancestry controls, 6,152 African American cases, 3,918 African American controls, 1,234 Latino cases, 3,090 Latino controls	1,979 European ancestry cases, 142,626 European ancestry controls	1q21.3	""	CRTC2	""	""	ENSG00000160741			rs10559-A	rs10559	0	10559	3_prime_UTR_variant	0	0.7	1E-8	8	""	0.95609	[0.94-0.97]	Affymetrix [7585078] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153927052	rs10908557	2017-03-22	27798627	Barban N	2016-10-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27798627	Genome-wide analysis identifies 12 loci influencing human reproductive behavior.	Age at first birth	189,656 European ancestry women, 48,408 European ancestry men	""	1q21.3	CRTC2, CREB3L4, GATAD2B, SLC39A1, DENND4B	CRTC2	""	""	ENSG00000160741			rs10908557-C	rs10908557	0	10908557	intron_variant	0	0.695	6E-10	9.22184874961636	""	0.091	NR unit increase	Illumina [2400000] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153797015	rs112780312	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		1q21.3	NR	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs112780312-A	rs112780312	0	112780312	intron_variant	0	NR	4E-9	8.39794000867204	""	5.899	z-score decrease	Affymetrix, Illumina [9295118] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153798128	rs4391701	2022-11-23	35164939	van der Meer D	2022-02-11	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35164939	Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology.	Brain morphology (MOSTest)	33,735 white British ancestry individuals		1q21.3	""	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs4391701-?	rs4391701	0	4391701	intron_variant	0	NR	4E-16	15.397940008672	""		""	NR [9061072] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153797015	rs112780312	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance	257,841 European ancestry individuals		1q21.3	Intergenic	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs112780312-A	rs112780312	0	112780312	intron_variant	0	0.2761	4E-11	10.397940008672	""	0.0212	[0.015-0.027] unit decrease	Affymetrix, Illumina [10100000] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153798128	rs4391701	2020-10-23	32665545	van der Meer D	2020-07-14	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/32665545	Understanding the genetic determinants of the brain with MOSTest.	Brain morphology (MOSTest)	26,502 European ancestry individuals		1q21.3	INTS3, SLC27A3, GATAD2B, DENND4B, CRTC2, SLC39A1, CREB3L4, JTB, RAB13, RPS27, NUP210L, TPM3, C1orf189, C1orf43, UBAP2L, HAX1	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs4391701-?	rs4391701	0	4391701	intron_variant	0	""	2E-15	14.698970004336	""		""	NR [7428630] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153886873	rs12033835	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		1q21.3	Intergenic	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs12033835-T	rs12033835	0	12033835	intron_variant	0	0.6944	2E-12	11.698970004336	(MTAG)	0.01	[0.0073-0.0127] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153927052	rs10908557	2018-08-06	27798627	Barban N	2016-10-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27798627	Genome-wide analysis identifies 12 loci influencing human reproductive behavior.	Age at first birth	48,408 European ancestry men	""	1q21.3	CRTC2, CREB3L4, GATAD2B, SLC39A1, DENND4B	CRTC2	""	""	ENSG00000160741			rs10908557-C	rs10908557	0	10908557	intron_variant	0	0.695	3E-7	6.52287874528034	""	0.185	NR unit increase	Illumina [2400000] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153768982	rs11583896	2022-10-26	36150907	Hatoum AS	2022-07-14	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/36150907	Genome-wide Association Study Shows That Executive Functioning Is Influenced by GABAergic Processes and Is a Neurocognitive Genetic Correlate of Psychiatric Disorders.	Common executive function	427,037 European ancestry individuals		1q21.3	""	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs11583896-?	rs11583896	0	11583896	non_coding_transcript_exon_variant	0	NR	2E-8	7.69897000433602	""		""	Affymetrix [7391068] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153787279	rs113422987	2020-10-23	32665545	van der Meer D	2020-07-14	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/32665545	Understanding the genetic determinants of the brain with MOSTest.	Subcortical volume (MOSTest)	26,502 European ancestry individuals		1q21.3	LACTBL1, C1orf234, KDM1A, LUZP1, HTR1D	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs113422987-?	rs113422987	0	113422987	intron_variant	0	""	1E-10	10	""		""	NR [7428630] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153943800	rs6666703	2022-03-28	33821002	Naqvi S	2021-04-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33821002	Shared heritability of human face and brain shape.	Brain shape (segment 15)	19,670 European ancestry individuals		1q21.3	""	CREB3L4	""	""	ENSG00000143578			rs6666703-?	rs6666703	0	6666703	intron_variant	0	NR	4E-9	8.39794000867204	""		""	NR [9705931] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153822673	rs4612664	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken	430,445 European ancestry individuals		1q21.3	Intergenic	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs4612664-T	rs4612664	0	4612664	intron_variant	0	0.6852	2E-10	9.69897000433602	""	0.0156	[0.011-0.02] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153875689	rs11264567	2018-06-27	29527006	Warrier V	2018-03-12	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29527006	Genome-wide analyses of self-reported empathy: correlations with autism, schizophrenia, and anorexia nervosa.	Empathy quotient	22,318 European ancestry males, 24,543 European ancestry females		1q21.3	GATAD2B, DENND4B, CRTC2, SLC39A1, CREB3L4	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs11264567-G	rs11264567	0	11264567	intron_variant	0	0.30279	3E-7	6.52287874528034	(males)	0.72	[0.45-0.99] unit increase	Illumina [9955952] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153797015	rs112780312	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		1q21.3	NR	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs112780312-G	rs112780312	0	112780312	intron_variant	0	0.277336	5E-11	10.301029995664	""	0.04610209	[0.032-0.06] unit increase	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153923276	rs10127983	2021-02-03	33398198	Conti DV	2021-01-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33398198	Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.	Prostate cancer	85,554 European ancestry cases, 10,368 African ancestry cases, 8,611 East Asian ancestry cases, 2,714 Hispanic cases, 91,972 European ancestry controls, 10,986 African ancestry controls, 18,809 East Asian ancestry controls, 5,239 Hispanic controls		1q21.3	NR	CRTC2	""	""	ENSG00000160741			rs10127983-T	rs10127983	0	10127983	intron_variant	0	NR	1E-19	19	""	1.066	[1.05-1.08]	Affymetrix, Illumina [29235255] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153986119	rs6672856	2020-01-28	31676860	Zhao B	2019-11-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/31676860	Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits.	Brain region volumes	19,629 British ancestry individuals		1q21.3	NR	NUP210L	""	""	ENSG00000143552			rs6672856-?	rs6672856	0	6672856	intron_variant	0	NR	1E-8	8	(left inferior lateral ventricle)		""	NR [9227495] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153822673	rs4612664	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		1q21.3	Intergenic	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs4612664-T	rs4612664	0	4612664	intron_variant	0	0.6851	1E-16	16	(MTAG)	0.016	[0.012-0.02] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153828080	rs4595397	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability	564,698 European ancestry individuals		1q21.3	Intergenic	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs4595397-T	rs4595397	0	4595397	intron_variant	0	0.6867	1E-11	11	""	0.0143	[0.01-0.018] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153797015	rs112780312	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		1q21.3	""	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs112780312-A	rs112780312	0	112780312	intron_variant	0	0.2863	1E-16	16	""	0.0096029	[0.0073-0.0119] unit decrease	Illumina [10675380] (imputed)	N
rs4845578	1	153829993	A	G	0.28827	7.15314737173e-11	0.0097316017404	0.00149316998503	13	1	153797015	rs112780312	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		1q21.3	Intergenic	GATAD2B, GATAD2B	""	""	ENSG00000261992, ENSG00000143614			rs112780312-A	rs112780312	0	112780312	intron_variant	0	0.2761	5E-16	15.301029995664	(MTAG)	0.0209	[0.016-0.026] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs4926172	19	13108622	C	T	0.49006	1.70751654127e-08	0.00530403425341	0.000940549822898	194	19	13096285	rs4334415	2020-07-21	32193296	Grasby KL	2020-03-01	Science	www.ncbi.nlm.nih.gov/pubmed/32193296	The genetic architecture of the human cerebral cortex.	Cortical surface area	33,992 European ancestry individuals	14,727 European ancestry individuals, 2,943 individuals	19p13.13	NR	DAND5 - NFIX	ENSG00000179284	ENSG00000008441	""	10711	10004	rs4334415-A	rs4334415	0	4334415	TF_binding_site_variant	1	0.5692	8E-9	8.09691001300806	(Superior Parietal)	16.81981	[11.11-22.53] unit decrease	Affymetrix, Illumina [NR]	N
rs4926172	19	13108622	C	T	0.49006	1.70751654127e-08	0.00530403425341	0.000940549822898	194	19	13113641	rs10411958	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance	257,841 European ancestry individuals		19p13.13	Intergenic	NFIX	""	""	ENSG00000008441			rs10411958-T	rs10411958	0	10411958	intron_variant	0	0.4687	2E-8	7.69897000433602	""	0.016	[0.01-0.022] unit increase	Affymetrix, Illumina [10100000] (imputed)	N
rs4926172	19	13108622	C	T	0.49006	1.70751654127e-08	0.00530403425341	0.000940549822898	194	19	13113641	rs10411958	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		19p13.13	""	NFIX	""	""	ENSG00000008441			rs10411958-?	rs10411958	0	10411958	intron_variant	0	NR	4E-9	8.39794000867204	""		""	NR [6307410] (imputed)	N
rs4926172	19	13108622	C	T	0.49006	1.70751654127e-08	0.00530403425341	0.000940549822898	194	19	13113641	rs10411958	2020-12-14	32042192	Ruth KS	2020-02-10	Nat Med	www.ncbi.nlm.nih.gov/pubmed/32042192	Using human genetics to understand the disease impacts of testosterone in men and women.	Sex hormone-binding globulin levels	180,726 European ancestry men		19p13.13	NR	NFIX	""	""	ENSG00000008441			rs10411958-C	rs10411958	0	10411958	intron_variant	0	0.532552	2E-7	6.69897000433602	""	0.00656776	[0.0041-0.009] unit increase	Affymetrix [16582614] (imputed)	N
rs4926172	19	13108622	C	T	0.49006	1.70751654127e-08	0.00530403425341	0.000940549822898	194	19	13113641	rs10411958	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		19p13.13	NR	NFIX	""	""	ENSG00000008441			rs10411958-T	rs10411958	0	10411958	intron_variant	0	0.49006	3E-8	7.52287874528034	""	0.03487871	[0.023-0.047] unit increase	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs4926172	19	13108622	C	T	0.49006	1.70751654127e-08	0.00530403425341	0.000940549822898	194	19	13108622	rs4926172	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		19p13.13	NR	NFIX	""	""	ENSG00000008441			rs4926172-?	rs4926172	0	4926172	intron_variant	0	NR	4E-7	6.39794000867204	""	5.074	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4926172	19	13108622	C	T	0.49006	1.70751654127e-08	0.00530403425341	0.000940549822898	194	19	13114434	rs10413329	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		19p13.13	NFIX	NFIX	""	""	ENSG00000008441			rs10413329-A	rs10413329	0	10413329	intron_variant	0	NR	2E-9	8.69897000433602	""	0.017926283	[0.012-0.024] unit increase	Affymetrix [NR]	N
rs4926172	19	13108622	C	T	0.49006	1.70751654127e-08	0.00530403425341	0.000940549822898	194	19	13113641	rs10411958	2020-12-14	32042192	Ruth KS	2020-02-10	Nat Med	www.ncbi.nlm.nih.gov/pubmed/32042192	Using human genetics to understand the disease impacts of testosterone in men and women.	Sex hormone-binding globulin levels adjusted for BMI	180,094 European ancestry men		19p13.13	NR	NFIX	""	""	ENSG00000008441			rs10411958-C	rs10411958	0	10411958	intron_variant	0	0.532552	2E-9	8.69897000433602	""	0.00680942	[0.0045-0.0091] unit increase	Affymetrix [16582621] (imputed)	N
rs4926172	19	13108622	C	T	0.49006	1.70751654127e-08	0.00530403425341	0.000940549822898	194	19	13113641	rs10411958	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		19p13.13	NR	NFIX	""	""	ENSG00000008441			rs10411958-T	rs10411958	0	10411958	intron_variant	0	NR	3E-9	8.52287874528034	""	5.948	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs589104	11	105807772	G	T	0.479125	1.18154981161e-09	0.0056257838163	0.00092487847061	147	11	105814770	rs1939800	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		11q22.3	Intergenic	GRIA4	""	""	ENSG00000152578			rs1939800-T	rs1939800	0	1939800	intron_variant	0	0.3851	1E-10	10	(MTAG)	0.0086	[0.0061-0.0111] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs589104	11	105807772	G	T	0.479125	1.18154981161e-09	0.0056257838163	0.00092487847061	147	11	105827909	rs7116046	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		11q22.3	NR	GRIA4	""	""	ENSG00000152578			rs7116046-T	rs7116046	0	7116046	intron_variant	0	NR	3E-8	7.52287874528034	""	5.526	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs589104	11	105807772	G	T	0.479125	1.18154981161e-09	0.0056257838163	0.00092487847061	147	11	105814770	rs1939800	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		11q22.3	Intergenic	GRIA4	""	""	ENSG00000152578			rs1939800-T	rs1939800	0	1939800	intron_variant	0	0.3812	2E-11	10.698970004336	(MTAG)	0.0124	[0.0089-0.0159] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs589104	11	105807772	G	T	0.479125	1.18154981161e-09	0.0056257838163	0.00092487847061	147	11	105814770	rs1939800	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		11q22.3	Intergenic	GRIA4	""	""	ENSG00000152578			rs1939800-T	rs1939800	0	1939800	intron_variant	0	0.3815	3E-13	12.5228787452803	(MTAG)	0.0124	[0.0091-0.0157] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs589104	11	105807772	G	T	0.479125	1.18154981161e-09	0.0056257838163	0.00092487847061	147	11	105845562	rs592656	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken	430,445 European ancestry individuals		11q22.3	Intergenic	RNU6-277P, GRIA4	""	""	ENSG00000252081, ENSG00000152578			rs592656-G	rs592656	0	592656	non_coding_transcript_exon_variant	0	0.363	4E-8	7.39794000867204	""	0.0129	[0.0082-0.0176] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs589104	11	105807772	G	T	0.479125	1.18154981161e-09	0.0056257838163	0.00092487847061	147	11	105814770	rs1939800	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		11q22.3	""	GRIA4	""	""	ENSG00000152578			rs1939800-T	rs1939800	0	1939800	intron_variant	0	0.3833	2E-14	13.698970004336	""	0.00827494	[0.0062-0.0104] unit increase	Illumina [10675380] (imputed)	N
rs589104	11	105807772	G	T	0.479125	1.18154981161e-09	0.0056257838163	0.00092487847061	147	11	105812839	rs641574	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		11q22.3	Intergenic	GRIA4	""	""	ENSG00000152578			rs641574-A	rs641574	0	641574	intron_variant	0	0.6142	1E-11	11	(MTAG)	0.016	[0.011-0.021] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39976128	rs132570	2019-09-04	31374203	Lam M	2019-08-01	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/31374203	Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy)	328,917 individuals with educational attainment measurements, 107,207 individuals with cognitive ability measurements, 77,096 European ancestry schizophrenia cases, 43,456 European ancestry controls		22q13.1	CACNA1I	CACNA1I	""	""	ENSG00000100346			rs132570-?	rs132570	0	132570	intron_variant	0	NR	1E-11	11	""	0.013624602	[0.0097-0.0176] unit increase	NR [7306098]	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39976133	rs132571	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		22q13.1	Intergenic	CACNA1I	""	""	ENSG00000100346			rs132571-A	rs132571	0	132571	intron_variant	0	0.4744	3E-12	11.5228787452803	(MTAG)	0.0115	[0.0082-0.0148] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39976186	rs5750853	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		22q13.1	NR	CACNA1I	""	""	ENSG00000100346			rs5750853-T	rs5750853	0	5750853	intron_variant	0	NR	3E-10	9.52287874528034	""	6.321	z-score decrease	Affymetrix, Illumina [9295118] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39976186	rs5750853	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		22q13.1	CACNA1I	CACNA1I	""	""	ENSG00000100346			rs5750853-T	rs5750853	0	5750853	intron_variant	0	NR	3E-11	10.5228787452803	""	0.020491894	[0.014-0.027] unit decrease	Affymetrix [NR]	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39976186	rs5750853	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		22q13.1	""	CACNA1I	""	""	ENSG00000100346			rs5750853-?	rs5750853	0	5750853	intron_variant	0	NR	2E-9	8.69897000433602	""		""	NR [6307410] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39975307	rs5757736	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		22q13.1	NR	CACNA1I	""	""	ENSG00000100346			rs5757736-G	rs5757736	0	5757736	intron_variant	0	0.432406	3E-9	8.52287874528034	""	0.03772907	[0.025-0.05] unit increase	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39975691	rs8139773	2020-10-07	32606422	Wu Y	2020-06-30	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/32606422	Multi-trait analysis for genome-wide association study of five psychiatric disorders.	Schizophrenia (MTAG)	65,967 individuals		22q13.1	NR	CACNA1I	""	""	ENSG00000100346			rs8139773-?	rs8139773	0	8139773	intron_variant	0	""	1E-9	9	""		""	NR [8377093]	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	40000221	rs5750857	2021-04-27	33686288	Peyrot WJ	2021-03-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33686288	Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS.	Schizophrenia vs autism spectrum disorder (ordinary least squares (OLS))	40,675 schizophrenia cases, 18,381 autism spectrum disorder cases		22q13.1	""	CACNA1I	""	""	ENSG00000100346			rs5750857-?	rs5750857	0	5750857	intron_variant	0	NR	2E-10	9.69897000433602	""	0.0191	NR unit increase	NR [4484088] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39976128	rs132570	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		22q13.1	CACNA1I	CACNA1I	""	""	ENSG00000100346			rs132570-A	rs132570	0	132570	intron_variant	0	NR	2E-11	10.698970004336	""	0.02010179	[0.014-0.026] unit increase	Affymetrix [NR]	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	40011273	rs3788568	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		22q13.1	CACNA1I	CACNA1I	""	""	ENSG00000100346			rs3788568-T	rs3788568	0	3788568	intron_variant	0	NR	9E-10	9.04575749056067	""	0.018673336	[0.013-0.025] unit decrease	Affymetrix [NR]	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	40006035	rs3788567	2016-07-23	26198764	Goes FS	2015-07-21	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/26198764	Genome-wide association study of schizophrenia in Ashkenazi Jews.	Schizophrenia	592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls		22q13.1	NR	CACNA1I	""	""	ENSG00000100346			rs3788567-T	rs3788567	0	3788567	intron_variant	0	NR	2E-11	10.698970004336	""	1.08	[NR]	Illumina [7158791] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39975914	rs28631967	2021-06-29	32895543	de la Fuente J	2020-09-07	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/32895543	A general dimension of genetic sharing across diverse cognitive traits inferred from molecular data.	Verbal-numerical reasoning	171,304 British ancestry individuals		22q13.1	""	CACNA1I	""	""	ENSG00000100346			rs28631967-?	rs28631967	0	28631967	intron_variant	0	NR	1E-9	9	""		""	NR [7857346] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	40009336	rs1008677	2021-04-27	33686288	Peyrot WJ	2021-03-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33686288	Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS.	Schizophrenia vs Tourette's syndrome and other tic disorders (ordinary least squares (OLS))	40,675 schizophrenia cases, 4,819 Tourette's syndrome cases		22q13.1	""	CACNA1I	""	""	ENSG00000100346			rs1008677-?	rs1008677	0	1008677	intron_variant	0	NR	1E-11	11	""	0.025	NR unit increase	NR [4502103] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	40010636	rs5757748	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		22q13.1	Intergenic	CACNA1I	""	""	ENSG00000100346			rs5757748-A	rs5757748	0	5757748	intron_variant	0	0.3495	2E-10	9.69897000433602	(MTAG)	0.0152	[0.01-0.02] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	40006986	rs926231	2019-08-19	31268507	Periyasamy S	2019-07-03	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/31268507	Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study.	Schizophrenia	816 Indian ancestry cases, 900 Indian ancestry controls, 505 Indian ancestry cases and 871 Indian ancestry controls from 405 families, up to 36,989 European and unknown ancestry cases, up to 113,075 European and unknown ancestry controls		22q13.1	NR	CACNA1I	""	""	ENSG00000100346			rs926231-?	rs926231	0	926231	intron_variant	0	NR	2E-11	10.698970004336	""		""	Illumina [up to 5582932] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39942234	rs5757717	2016-07-23	26198764	Goes FS	2015-07-21	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/26198764	Genome-wide association study of schizophrenia in Ashkenazi Jews.	Schizophrenia	592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls		22q13.1	NR	RPS19BP1 - CACNA1I	ENSG00000187051	ENSG00000100346	""	13468	24524	rs5757717-C	rs5757717	0	5757717	regulatory_region_variant	1	NR	6E-10	9.22184874961636	""	1.0752687	[NR]	Illumina [7158791] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39942234	rs5757717	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		22q13.1	RPS19BP1	RPS19BP1 - CACNA1I	ENSG00000187051	ENSG00000100346	""	13468	24524	rs5757717-T	rs5757717	0	5757717	regulatory_region_variant	1	NR	5E-8	7.30102999566398	""	0.016741602	[0.011-0.023] unit increase	Affymetrix [NR]	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39967430	rs5757730	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		22q13.1	""	CACNA1I	""	""	ENSG00000100346			rs5757730-A	rs5757730	0	5757730	intron_variant	0	0.4875	2E-10	9.69897000433602	(conditional-joint)	0.009	[0.0063-0.0117] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39967430	rs5757730	2018-12-17	29483656	Pardinas AF	2018-02-26	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29483656	Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.	Schizophrenia	40,675 European ancestry cases, 64,643 European ancestry controls	1,651 European ancestry cases, 4,111 cases, 142,717 European ancestry controls, 11,507 controls	22q13.1	LOC100506472, MGAT3, TAB1, CACNA1I, RPS19BP1	CACNA1I	""	""	ENSG00000100346			rs5757730-?	rs5757730	0	5757730	intron_variant	0	NR	2E-12	11.698970004336	""	1.0741138	[1.05-1.09]	Illumina [8000000] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39972162	rs3788556	2019-02-06	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Educational attainment (years of education)	approximately 455,000 European ancestry individuals		22q13.1	""	CACNA1I	""	""	ENSG00000100346			rs3788556-?	rs3788556	0	3788556	intron_variant	0	NR	8E-11	10.0969100130081	""		""	NR [~ 8900000] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39972162	rs3788556	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		22q13.1	CACNA1I	CACNA1I	""	""	ENSG00000100346			rs3788556-T	rs3788556	0	3788556	intron_variant	0	NR	2E-9	8.69897000433602	""	0.017985191	[0.012-0.024] unit increase	Affymetrix [NR]	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39972162	rs3788556	2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals		22q13.1	NR	CACNA1I	""	""	ENSG00000100346			rs3788556-C	rs3788556	0	3788556	intron_variant	0	0.56038034270415	5E-8	7.30102999566398	(IGP39)	0.1799	[0.12-0.24] unit increase	Illumina [~ 2500000] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39942234	rs5757717	2020-02-11	31835028	Cross-Disorder Group of the Psychiatric Genomics Consortium	2019-12-01	Cell	www.ncbi.nlm.nih.gov/pubmed/31835028	Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy)	19,009 European ancestry ADHD cases, 3,495 European ancestry anorexia cases, 18,381 European ancestry autism cases, 20,352 European ancestry bipolar disorder cases, 130,664 European ancestry major depression cases, 2,688 European ancestry OCD cases, 33,640 European ancestry schizophrenia cases, 4,645 European ancestry Tourette's cases, 494,162 European ancestry controls		22q13.1	RPS19BP1, ATF4	RPS19BP1 - CACNA1I	ENSG00000187051	ENSG00000100346	""	13468	24524	rs5757717-?	rs5757717	0	5757717	regulatory_region_variant	1	""	9E-11	10.0457574905607	""		""	NR [6786993] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39955873	rs9611198	2012-09-29	22883433	Irish Schizophrenia Genomics Consortium and the Wellcome Trust Case Control Consortium 2	2012-08-07	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22883433	Genome-wide association study implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex locus in schizophrenia.	Schizophrenia	1,606 European ancestry cases, 1,794 European ancestry controls	13,195 European ancestry cases, 31,021 European ancestry controls	22q13.1	CACNA1I	RPS19BP1 - CACNA1I	ENSG00000187051	ENSG00000100346	""	27107	10885	rs9611198-C	rs9611198	0	9611198	TF_binding_site_variant	1	0.458	8E-6	5.09691001300806	""	1.22	[1.11-1.34]	Affymetrix [6212339]	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39966547	rs7288455	2021-07-27	33479212	Yao X	2021-01-21	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/33479212	Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders.	Schizophrenia (MTAG)	at least 33,640 European ancestry cases, at least 43,456 European ancestry controls		22q13.1	NR	RPS19BP1 - CACNA1I	ENSG00000187051	ENSG00000100346	""	37781	211	rs7288455-A	rs7288455	0	7288455	intergenic_variant	1	0.3698	8E-9	8.09691001300806	""	0.0661519	[0.044-0.089] unit decrease	NR [NR]	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39966547	rs7288455	2022-04-05	34855049	Pasman JA	2021-12-02	Behav Genet	www.ncbi.nlm.nih.gov/pubmed/34855049	Genetic Risk for Smoking: Disentangling Interplay Between Genes and Socioeconomic Status.	Educational attainment	451,800 European or unknown ancestry individuals		22q13.1	""	RPS19BP1 - CACNA1I	ENSG00000187051	ENSG00000100346	""	37781	211	rs7288455-?	rs7288455	0	7288455	intergenic_variant	1	NR	2E-11	10.698970004336	""		""	NR [1300000]	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39967430	rs5757730	2019-12-23	31740837	Lam M	2019-11-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/31740837	Comparative genetic architectures of schizophrenia in East Asian and European populations.	Schizophrenia	22,778 East Asian ancestry cases, 35,362 East Asian ancestry controls, 33,640 European ancestry cases, 43,456 European ancestry controls		22q13.1	NR	CACNA1I	""	""	ENSG00000100346			rs5757730-?	rs5757730	0	5757730	intron_variant	0	NR	8E-11	10.0969100130081	""	1.0732608	[1.05-1.09]	Affymetrix, Illumina [12447948] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39967430	rs5757730	2017-11-10	28991256	Li Z	2017-10-09	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28991256	Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.	Schizophrenia	7,699 Chinese ancestry cases, 35,476 European ancestry cases, 18,327 Chinese ancestry controls, 46,839 European ancestry controls	4,384 Chinese ancestry cases, 5,770 Chinese ancestry controls	22q13.1	CACNA1I	CACNA1I	""	""	ENSG00000100346			rs5757730-G	rs5757730	0	5757730	intron_variant	0	NR	2E-10	9.69897000433602	""	1.0718113	[1.05-1.09]	Affymetrix, Illumina [up to 5107227] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39967430	rs5757730	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		22q13.1	NR	CACNA1I	""	""	ENSG00000100346			rs5757730-?	rs5757730	0	5757730	intron_variant	0	NR	1E-7	7	""	5.336	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39967430	rs5757730	2019-02-21	30285260	Ikeda M	2018-10-03	Schizophr Bull	www.ncbi.nlm.nih.gov/pubmed/30285260	Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.	Schizophrenia	14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls		22q13.1	CACNA1I	CACNA1I	""	""	ENSG00000100346			rs5757730-G	rs5757730	0	5757730	intron_variant	0	NR	2E-10	9.69897000433602	""	1.0729614	[1.05-1.09]	Illumina [6627481] (imputed)	N
rs589104	11	105807772	G	T	0.479125	1.18154981161e-09	0.0056257838163	0.00092487847061	147	11	105746052	rs590414	2021-11-02	34446935	Karlsson Linner R	2021-08-26	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/34446935	Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.	Externalizing behaviour (multivariate analysis)	up to 53,293 European ancestry Attention-deficit/hyperactivity disorder individuals, up to 164,684 European ancestry problematic alcohol use individuals, up to 186,875 European ancestry lifetime cannabis use individuals, up to 357,187 European ancestry individuals measuring  reverse-coded age at first sexual intercourse, up to 336,121 European ancestry individuals measuring number of sexual partners, up to 426,379 European ancestry individuals measuring general risk tolerance, up to 1,251,809  European ancestry individuals measuring lifetime smoking initiation		11q22.3	""	GRIA4	""	""	ENSG00000152578			rs590414-A	rs590414	0	590414	intron_variant	0	0.5	3E-10	9.52287874528034	""	0.007	[0.005-0.009] unit increase	NR [NR] (imputed)	N
rs589104	11	105807772	G	T	0.479125	1.18154981161e-09	0.0056257838163	0.00092487847061	147	11	105746052	rs590414	2021-07-27	34211149	Mills MC	2021-07-01	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/34211149	Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour.	Age at first sexual intercourse	397,338 European ancestry individuals		11q22.3	GRIA4	GRIA4	""	""	ENSG00000152578			rs590414-A	rs590414	0	590414	intron_variant	0	0.497739	2E-10	9.69897000433602	""	0.0134661	[0.0094-0.0175] unit decrease	NR [16516521] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39992246	rs111672076	2021-06-29	32895543	de la Fuente J	2020-09-07	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/32895543	A general dimension of genetic sharing across diverse cognitive traits inferred from molecular data.	Cognitive traits (MTAG)	331,679 British ancestry individuals		22q13.1	""	CACNA1I	""	""	ENSG00000100346			rs111672076-?	rs111672076	0	111672076	intron_variant	0	NR	5E-8	7.30102999566398	""		""	NR [7857346] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	40002570	rs5995757	2020-01-29	31844048	Hill WD	2019-12-16	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/31844048	Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income.	Household income (MTAG)	505,541 British and unknown ancestry individuals		22q13.1	CACNA1I	CACNA1I	""	""	ENSG00000100346			rs5995757-C	rs5995757	0	5995757	intron_variant	0	0.426	7E-11	10.1549019599857	""	0.013329337	[0.0093-0.0173] unit increase	Affymetrix [up to 18485882] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	39982721	rs132575	2018-01-12	29186694	Lam M	2017-11-28	Cell Rep	www.ncbi.nlm.nih.gov/pubmed/29186694	Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.	Cognitive ability (MTAG)	436,124 European ancestry individuals		22q13.1	CACNA1I	CACNA1I	""	""	ENSG00000100346			rs132575-?	rs132575	0	132575	intron_variant	0	NR	2E-8	7.69897000433602	""	5.625	z score decrease	Affymetrix, Illumina, Perlegen [7333576] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	40019773	rs12170452	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		22q13.1	Intergenic	CACNA1I	""	""	ENSG00000100346			rs12170452-A	rs12170452	0	12170452	intron_variant	0	0.4507	7E-17	16.1549019599857	(MTAG)	0.011	[0.0085-0.0135] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	40019773	rs12170452	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		22q13.1	""	CACNA1I	""	""	ENSG00000100346			rs12170452-A	rs12170452	0	12170452	intron_variant	0	0.4445	9E-23	22.0457574905607	""	0.0103416	[0.0083-0.0124] unit increase	Illumina [10675380] (imputed)	N
rs5750853	22	39976186	T	C	0.432406	2.06430314349e-09	0.00584333960257	0.00097508203566	205	22	40019773	rs12170452	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		22q13.1	""	CACNA1I	""	""	ENSG00000100346			rs12170452-A	rs12170452	0	12170452	intron_variant	0	0.4507	8E-14	13.0969100130081	""	0.0105	[0.0078-0.0132] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44742064	rs1569723	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Graves' disease	1,678 European ancestry cases, 456,942 European ancestry controls, 2,809 East Asian ancestry cases, 172,656 East Asian ancestry controls		20q13.12	""	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	13249	4853	rs1569723-A	rs1569723	0	1569723	regulatory_region_variant	1	NR	2E-12	11.698970004336	""	0.1641	[0.12-0.21] unit increase	Affymetrix, Illumina [25841587] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44742064	rs1569723	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Graves' disease	2,809 East Asian ancestry cases, 172,656 East Asian ancestry controls		20q13.12	""	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	13249	4853	rs1569723-A	rs1569723	0	1569723	regulatory_region_variant	1	0.614881717	1E-8	8	""	0.16323031	[0.11-0.22] unit increase	Illumina [13429311] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44742064	rs1569723	2020-03-03	28369058	Folkersen L	2017-04-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28369058	Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.	Blood protein levels in cardiovascular risk	3,394 European ancestry individuals	2,639 individuals	20q13.12	CD40	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	13249	4853	rs1569723-C	rs1569723	0	1569723	regulatory_region_variant	1	0.28	2E-121	120.698970004336	""	0.39	unit decrease	Illumina [5270624] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44742064	rs1569723	2017-06-02	28067908	de Lange KM	2017-01-09	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28067908	Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.	Crohn's disease	12,194 European and unknown ancestry cases, 28,072 European and unknown ancestry controls		20q13.12	CD40, SLC12A5, NCOA5	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	13249	4853	rs1569723-?	rs1569723	0	1569723	regulatory_region_variant	1	""	2E-7	6.69897000433602	""		""	Illumina [9560910] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44742064	rs1569723	2017-06-02	28067908	de Lange KM	2017-01-09	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28067908	Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.	Inflammatory bowel disease	25,042 European and unknown ancestry cases, 34,915 European and unknown ancestry controls		20q13.12	CD40, SLC12A5, NCOA5	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	13249	4853	rs1569723-?	rs1569723	0	1569723	regulatory_region_variant	1	""	2E-6	5.69897000433602	""		""	Illumina [9725440] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44742064	rs1569723	2021-02-26	32514122	Ishigaki K	2020-06-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32514122	Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.	Graves' disease	2,176 Japanese ancestry cases, 210,277 Japanese ancestry controls		20q13.12	""	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	13249	4853	rs1569723-A	rs1569723	0	1569723	regulatory_region_variant	1	0.614705531	4E-9	8.39794000867204	""	1.2041003	[1.131835944-1.280978518]	Illumina [8919992] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44742064	rs1569723	2013-02-12	23128233	Jostins L	2012-11-01	Nature	www.ncbi.nlm.nih.gov/pubmed/23128233	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	Inflammatory bowel disease	12,924 European ancestry cases, 21,442 European ancestry controls	25,683 European ancestry cases, 17,015 European ancestry controls	20q13.12	CD40, MMP9, PLTP	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	13249	4853	rs1569723-C	rs1569723	0	1569723	regulatory_region_variant	1	0.259	1E-13	13	""	1.091	[1.056-1.126]	Affymetrix, Illumina [1230000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44742064	rs1569723	2012-04-25	22446961	Lee YC	2012-03-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22446961	Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis.	Kawasaki disease	622 Han Chinese ancestry cases, 1,107 Han Chinese ancestry controls	261 Han Chinese ancestry cases, 550 Han Chinese ancestry controls	20q13.12	CD40	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	13249	4853	rs1569723-A	rs1569723	0	1569723	regulatory_region_variant	1	0.5480	6E-9	8.22184874961636	""	1.415	[1.256-1.594]	Affymetrix [716935]	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44742064	rs1569723	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		20q13.12	Intergenic	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	13249	4853	rs1569723-A	rs1569723	0	1569723	regulatory_region_variant	1	0.743	3E-14	13.5228787452803	(MTAG)	0.0144	[0.011-0.018] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44742064	rs1569723	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken	430,445 European ancestry individuals		20q13.12	Intergenic	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	13249	4853	rs1569723-C	rs1569723	0	1569723	regulatory_region_variant	1	0.257	9E-9	8.04575749056068	""	0.0149	[0.0098-0.02] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44724305	rs6131010	2018-07-19	29662059	Howard DM	2018-04-16	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29662059	Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.	Depression (broad)	113,769 British ancestry cases, 208,811 British ancestry controls		20q13.12	NR	NCOA5 - RPL13P2	ENSG00000124160	ENSG00000213820	""	5704	3852	rs6131010-G	rs6131010	0	6131010	upstream_gene_variant	1	0.7402	7E-8	7.15490195998574	""	0.0073	[0.0048-0.0098] unit decrease	NR [7666894] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44724305	rs6131010	2022-09-28	34282934	Fan W	2021-07-20	mSystems	www.ncbi.nlm.nih.gov/pubmed/34282934	Association between Human Genetic Variants and the Vaginal Bacteriome of Pregnant Women.	Vaginal microbiome presence (c_Actinobacteria)	315 Chinese ancestry individuals		20q13.12	""	NCOA5 - RPL13P2	ENSG00000124160	ENSG00000213820	""	5704	3852	rs6131010-A	rs6131010	0	6131010	upstream_gene_variant	1	NR	2E-6	5.69897000433602	""	0.3838	[0.2579-0.5712]	Illumina [492582]	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44724305	rs6131010	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		20q13.12	""	NCOA5 - RPL13P2	ENSG00000124160	ENSG00000213820	""	5704	3852	rs6131010-A	rs6131010	0	6131010	upstream_gene_variant	1	0.2682	6E-10	9.22184874961636	""	0.00729982	[0.005-0.0096] unit decrease	Illumina [10675380] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44724305	rs6131010	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Hyperthyroidism	3,557 European ancestry cases, 456,942 European ancestry controls, 994 East Asian ancestry cases, 172,656 East Asian ancestry controls		20q13.12	""	NCOA5 - RPL13P2	ENSG00000124160	ENSG00000213820	""	5704	3852	rs6131010-G	rs6131010	0	6131010	upstream_gene_variant	1	NR	4E-8	7.39794000867204	""	0.1306	[0.084-0.177] unit increase	Affymetrix, Illumina [25841580] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44730245	rs6032660	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	Unswitched memory B cell %lymphocyte	3,656 Sardinian (founder/genetic isolate) ancestry individuals		20q13.12	""	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	1430	16672	rs6032660-A	rs6032660	0	6032660	downstream_gene_variant	1	0.6357900000000001	7E-9	8.15490195998574	""	0.1525	[0.1-0.2] unit decrease	Illumina [18238287] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44732089	rs2024568	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		20q13.12	""	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	3274	14828	rs2024568-T	rs2024568	0	2024568	intergenic_variant	1	0.2535	2E-9	8.69897000433602	""	0.0097	[0.0066-0.0128] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44732089	rs2024568	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		20q13.12	Intergenic	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	3274	14828	rs2024568-T	rs2024568	0	2024568	intergenic_variant	1	0.2535	6E-13	12.2218487496164	(MTAG)	0.0108	[0.0079-0.0137] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44732089	rs2024568	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		20q13.12	Intergenic	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	3274	14828	rs2024568-T	rs2024568	0	2024568	intergenic_variant	1	0.2464	4E-9	8.39794000867204	(MTAG)	0.0156	[0.01-0.021] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44734310	rs6032662	2020-02-10	31604244	International Multiple Sclerosis Genetics Consortium	2019-09-01	Science	www.ncbi.nlm.nih.gov/pubmed/31604244	Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility.	Multiple sclerosis	14,802 European and unknown ancestry cases, 26,703 European and unknown ancestry controls	32,627 European and unknown ancestry cases, 41,672 European and unknown ancestry controls	20q13.12	NCOA5	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	5495	12607	rs6032662-C	rs6032662	0	6032662	intergenic_variant	1	NR	5E-19	18.301029995664	""	1.0995	NR	Affymetrix, Illumina [8278136] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44734310	rs6032662	2018-05-08	23143596	Eyre S	2012-12-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23143596	High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.	Rheumatoid arthritis (ACPA-positive)	up to 9,585 European ancestry cases, up to 33,742 European ancestry controls		20q13.12	CD40	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	5495	12607	rs6032662-?	rs6032662	0	6032662	intergenic_variant	1	0.76	1E-9	9	""	1.1676786	""	Illumina [129464] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44735854	rs6065926	2022-09-27	35396580	Trubetskoy V	2022-04-08	Nature	www.ncbi.nlm.nih.gov/pubmed/35396580	Mapping genomic loci implicates genes and synaptic biology in schizophrenia.	Schizophrenia	53,386 European ancestry cases, 77,258 European ancestry controls, 14,004 East Asian ancestry cases, 16,757 East Asian ancestry controls, 6,152 African American cases, 3,918 African American controls, 1,234 Latino cases, 3,090 Latino controls	1,979 European ancestry cases, 142,626 European ancestry controls	20q13.12	""	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	7039	11063	rs6065926-A	rs6065926	0	6065926	regulatory_region_variant	1	0.197	2E-6	5.69897000433602	""	1.04571	[1.03-1.06]	Affymetrix [7585078] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44735854	rs6065926	2022-03-28	35264221	Caron B	2022-03-09	Genome Med	www.ncbi.nlm.nih.gov/pubmed/35264221	Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes.	CD40 plasma levels	400 French ancestry individuals		20q13.12	""	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	7039	11063	rs6065926-G	rs6065926	0	6065926	regulatory_region_variant	1	NR	1E-10	10	""	0.15	[0.11-0.19] ng/mL decrease	Illumina [5201092] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44735854	rs6065926	2022-08-18	35545683	Sorosina M	2022-05-12	J Neurol	www.ncbi.nlm.nih.gov/pubmed/35545683	A multi-step genomic approach prioritized TBKBP1 gene as relevant for multiple sclerosis susceptibility.	Multiple sclerosis	1,701 Italian ancestry cases, 2,345 Italian ancestry controls	4,991 European ancestry cases, 8,028 European ancestry controls	20q13.12	""	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	7039	11063	rs6065926-A	rs6065926	0	6065926	regulatory_region_variant	1	NR	9E-9	8.04575749056068	""	1.16	[1.11-1.23]	Illumina [196524] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44739419	rs6032664	2017-05-11	27182965	Pickrell JK	2016-05-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27182965	Detection and interpretation of shared genetic influences on 42 human traits.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls		20q13.12	NCOA5, CD40	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	10604	7498	rs6032664-?	rs6032664	0	6032664	regulatory_region_variant	1	NR	7E-12	11.1549019599857	""	1.0649627	[1.05-1.08]	Illumina [13757430] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44739419	rs6032664	2017-12-01	28928442	Tian C	2017-09-19	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28928442	Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.	Tonsillectomy	60,098 European ancestry cases, 113,323 European ancestry controls		20q13.12	NCOA5, CD40	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	10604	7498	rs6032664-A	rs6032664	0	6032664	regulatory_region_variant	1	0.26	7E-12	11.1549019599857	""	1.07	[1.06-1.08]	Illumina [at least 560000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44740196	rs6074022	2016-07-24	26192919	Liu JZ	2015-07-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/26192919	Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.	Crohn's disease	5,956 European ancestry cases, 14,927 European ancestry controls	14,594 European ancestry cases, 26,715 European ancestry controls, 151 Iranian ancestry cases, 342 Iranian ancestry controls, 184 Indian ancestry cases, 990 Indian ancestry controls, 1,690 East Asian ancestry cases, 3,719 East Asian ancestry controls	20q13.12	NR	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	11381	6721	rs6074022-G	rs6074022	0	6074022	TF_binding_site_variant	1	0.2503	3E-12	11.5228787452803	(EA)	1.1011126	[1.07-1.13]	Affymetrix, Illumina [~ 9000000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44740196	rs6074022	2016-07-24	26192919	Liu JZ	2015-07-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/26192919	Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.	Inflammatory bowel disease	12,882 European ancestry cases, 21,770 European ancestry controls	25,273 European ancestry cases, 26,715 European ancestry controls, 548 Iranian ancestry cases, 342 Iranian ancestry control, 1,423 Indian ancestry cases, 990 Indian ancestry controls, 2,824 East Asian ancestry cases, 3,719 East Asian ancestry controls	20q13.12	NR	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	11381	6721	rs6074022-G	rs6074022	0	6074022	TF_binding_site_variant	1	0.2503	8E-11	10.0969100130081	(EA)	1.0770855	[1.05-1.1]	Affymetrix, Illumina [~ 9000000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44740196	rs6074022	2009-06-30	19525955	Bahlo M	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525955	Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.	Multiple sclerosis	1,618 European ancestry cases, 3,413 European ancestry controls	2,256 European ancestry cases, 2,310 European ancestry controls	20q13.12	CD40	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	11381	6721	rs6074022-G	rs6074022	0	6074022	TF_binding_site_variant	1	0.25	1E-7	7	""	1.2	[NR]	Illumina [302098]	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44740196	rs6074022	2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls		20q13.12	CD40	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017	""	11381	6721	rs6074022-C	rs6074022	0	6074022	TF_binding_site_variant	1	0.27	5E-6	5.30102999566398	""	1.15	[NR]	Affymetrix, Illumina [2529394]	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44747947	rs4810485	2020-11-24	33067605	Folkersen L	2020-10-16	Nat Metab	www.ncbi.nlm.nih.gov/pubmed/33067605	Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.	Tumor necrosis factor receptor superfamily member 5 levels	21,758 European ancestry individuals	9,173 individuals	20q13.12	""	CD40	""	""	ENSG00000101017			rs4810485-T	rs4810485	0	4810485	intron_variant	0	0.26	1E-414	414	""	0.4676	unit decrease	Affymetrix, Illumina [20300000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44747947	rs4810485	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	CD27 on unswitched memory B cell	3,656 Sardinian (founder/genetic isolate) ancestry individuals		20q13.12	""	CD40	""	""	ENSG00000101017			rs4810485-G	rs4810485	0	4810485	intron_variant	0	0.63127	6E-78	77.2218487496164	""	0.4783	[0.43-0.53] unit decrease	Illumina [18238284] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44747947	rs4810485	2018-06-29	28714469	Langefeld CD	2017-07-17	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28714469	Transancestral mapping and genetic load in systemic lupus erythematosus.	Systemic lupus erythematosus	6,748 European ancestry cases, 11,516 European ancestry controls, 2,970 African American cases, 2,452 African American controls, 1,872 Hispanic cases, 2,016 Hispanic controls		20q13.12	NCOA5, CD40	CD40	""	""	ENSG00000101017			rs4810485-?	rs4810485	0	4810485	intron_variant	0	NR	1E-8	8	""	1.43	[1.17-1.76]	Illumina [at least 5000000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44747947	rs4810485	2020-02-25	28915241	Ahsan M	2017-09-15	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/28915241	The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases.	Blood protein levels	up to 961 individuals		20q13.12	NR	CD40	""	""	ENSG00000101017			rs4810485-?	rs4810485	0	4810485	intron_variant	0	NR	5E-19	18.301029995664	(CD40)	0.496525	[0.39-0.61] unit increase	Illumina [11901634] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44749251	rs4239702	2014-08-05	24390342	Okada Y	2013-12-25	Nature	www.ncbi.nlm.nih.gov/pubmed/24390342	Genetics of rheumatoid arthritis contributes to biology and drug discovery.	Rheumatoid arthritis	up to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls	up to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls	20q13.12	CD40	CD40	""	""	ENSG00000101017			rs4239702-C	rs4239702	0	4239702	intron_variant	0	0.69	4E-18	17.397940008672	""	1.13	[1.10-1.16]	Affymetrix, Illumina [up to 9739303] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44749251	rs4239702	2014-08-05	24390342	Okada Y	2013-12-25	Nature	www.ncbi.nlm.nih.gov/pubmed/24390342	Genetics of rheumatoid arthritis contributes to biology and drug discovery.	Rheumatoid arthritis	up to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls	up to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls	20q13.12	CD40	CD40	""	""	ENSG00000101017			rs4239702-C	rs4239702	0	4239702	intron_variant	0	0.72	1E-16	16	(EA)	1.14	[1.11-1.18]	Affymetrix, Illumina [up to 9739303] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44749251	rs4239702	2019-01-25	30423114	Laufer VA	2018-11-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/30423114	Genetic Influences on Susceptibility to Rheumatoid Arthritis in African-Americans.	Rheumatoid arthritis	916 African American cases, 1,392 African American controls,	4,873 East Asian ancestry cases, 17,641 East Asian ancestry controls, 19,234 European ancestry cases, 61,654 European ancestry controls	20q13.12	CD40	CD40	""	""	ENSG00000101017			rs4239702-T	rs4239702	0	4239702	intron_variant	0	0.28	4E-14	13.397940008672	(EA)	0.13357	[0.099-0.168] unit decrease	Illumina [8380626] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44749251	rs4239702	2019-01-25	30423114	Laufer VA	2018-11-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/30423114	Genetic Influences on Susceptibility to Rheumatoid Arthritis in African-Americans.	Rheumatoid arthritis	916 African American cases, 1,392 African American controls,	4,873 East Asian ancestry cases, 17,641 East Asian ancestry controls, 19,234 European ancestry cases, 61,654 European ancestry controls	20q13.12	CD40	CD40	""	""	ENSG00000101017			rs4239702-T	rs4239702	0	4239702	intron_variant	0	NR	3E-14	13.5228787452803	""	0.0917533	[0.026-0.157] unit decrease	Illumina [8380626] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44749251	rs4239702	2020-07-24	32641083	Hillary RF	2020-07-08	Genome Med	www.ncbi.nlm.nih.gov/pubmed/32641083	Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults.	CD40 levels	982 Scottish ancestry individuals	""	20q13.12	NR	CD40	""	""	ENSG00000101017			rs4239702-T	rs4239702	0	4239702	intron_variant	0	0.28559	7E-15	14.1549019599857	""	0.39537	[0.3-0.5] unit decrease	Illumina [7903493] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44749251	rs4239702	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	IgD- CD27- B cell Absolute Count	3,656 Sardinian (founder/genetic isolate) ancestry individuals		20q13.12	""	CD40	""	""	ENSG00000101017			rs4239702-C	rs4239702	0	4239702	intron_variant	0	0.60025	2E-27	26.698970004336	""	0.2841	[0.23-0.33] unit increase	Illumina [18238287] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2015-12-03	25802187	Jiang DK	2015-04-28	Hepatology	www.ncbi.nlm.nih.gov/pubmed/25802187	Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B.	Chronic hepatitis B infection	2,514 Chinese ancestry cases, 1,130 Chinese ancestry controls	6,600 Chinese ancestry cases, 8,127 Chinese ancestry controls	20q13.12	CD40	CD40	""	""	ENSG00000101017			rs1883832-T	rs1883832	0	1883832	5_prime_UTR_variant	0	0.37	3E-15	14.5228787452803	""	1.19	[1.14-1.25]	Illumina [3680900] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2018-08-08	24532676	Kim K	2014-02-14	Ann Rheum Dis	www.ncbi.nlm.nih.gov/pubmed/24532676	High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.	Rheumatoid arthritis (ACPA-positive)	2,234 Korean ancestry cases, 7,065 Korean ancestry controls, 10,288 European ancestry cases, 35,502 European ancestry controls		20q13.12	CD40	CD40	""	""	ENSG00000101017			rs1883832-G	rs1883832	0	1883832	5_prime_UTR_variant	0	0.75	2E-13	12.698970004336	""	1.1363636	[1.1-1.18]	Illumina [133816] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2018-04-26	26974007	Ellinghaus D	2016-03-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/26974007	Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.	Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy)	8,726 European ancestry ankylosing spondylitis cases, 19,085 European ancestry Crohn’s disease cases, 6,530 European ancestry psoriasis cases, 3,408 European ancestry primary sclerosing cholangitis cases, 14,513 European ancestry ulcerative colitis cases, 34,213 European ancestry controls		20q13.12	CD40	CD40	""	""	ENSG00000101017			rs1883832-?	rs1883832	0	1883832	5_prime_UTR_variant	0	NR	4E-12	11.397940008672	(subset analysis)		""	Illumina [130052]	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2021-01-21	33106546	Johnson TA	2020-10-26	J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/33106546	Association of an IGHV3-66 gene variant with Kawasaki disease.	Kawasaki disease	1,276 East Asian ancestry cases, 5,086 East Asian ancestry controls	2,152 East Asian ancestry cases, 2,751 East Asian ancestry controls	20q13.12	CD40	CD40	""	""	ENSG00000101017			rs1883832-C	rs1883832	0	1883832	5_prime_UTR_variant	0	NR	2E-13	12.698970004336	""	1.28	[1.20-1.36]	Affymetrix, Illumina [6265045] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2021-02-17	33310728	Ha E	2020-12-11	Ann Rheum Dis	www.ncbi.nlm.nih.gov/pubmed/33310728	Large-scale meta-analysis across East Asian and European populations updated genetic architecture and variant-driven biology of rheumatoid arthritis, identifying 11 novel susceptibility loci.	Rheumatoid arthritis	14,361 European ancestry cases, 43,923 European ancestry controls, 8,267 East Asian ancestry cases, 244,741 East Asian ancestry controls		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-T	rs1883832	0	1883832	5_prime_UTR_variant	0	NR	1E-16	16	""	0.9	[0.88-0.92]	NR [13810676] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	CD25 on IgD- CD27- B cell	3,651 Sardinian (founder/genetic isolate) ancestry individuals		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-C	rs1883832	0	1883832	5_prime_UTR_variant	0	0.63146	3E-19	18.5228787452803	""	0.2306	[0.18-0.28] unit increase	Illumina [18236953] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	CD27 on CD24+ CD27+ B cell	3,657 Sardinian (founder/genetic isolate) ancestry individuals		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-C	rs1883832	0	1883832	5_prime_UTR_variant	0	0.63166	8E-120	119.096910013008	""	0.5841	[0.54-0.63] unit decrease	Illumina [18238311] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	CD27 on IgD+ CD24+ B cell	3,656 Sardinian (founder/genetic isolate) ancestry individuals		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-C	rs1883832	0	1883832	5_prime_UTR_variant	0	0.63156	3E-83	82.5228787452804	""	0.4972	[0.45-0.55] unit decrease	Illumina [18238284] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	CD27 on IgD- CD38- B cell	3,657 Sardinian (founder/genetic isolate) ancestry individuals		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-C	rs1883832	0	1883832	5_prime_UTR_variant	0	0.63166	4E-75	74.397940008672	""	0.4707	[0.42-0.52] unit decrease	Illumina [18238311] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	CD27 on IgD- CD38+ B cell	3,642 Sardinian (founder/genetic isolate) ancestry individuals		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-C	rs1883832	0	1883832	5_prime_UTR_variant	0	0.6322	4E-8	7.39794000867204	""	0.1431	[0.092-0.194] unit decrease	Illumina [18233708] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	CD20 on IgD- CD27- B cell	3,657 Sardinian (founder/genetic isolate) ancestry individuals		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-C	rs1883832	0	1883832	5_prime_UTR_variant	0	0.63166	5E-13	12.301029995664	""	0.1869	[0.14-0.24] unit decrease	Illumina [18238311] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	CD27 on IgD- CD38dim B cell	3,657 Sardinian (founder/genetic isolate) ancestry individuals		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-C	rs1883832	0	1883832	5_prime_UTR_variant	0	0.63166	6E-147	146.221848749616	""	0.6404	[0.59-0.69] unit decrease	Illumina [18238311] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	CD27 on memory B cell	3,657 Sardinian (founder/genetic isolate) ancestry individuals		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-C	rs1883832	0	1883832	5_prime_UTR_variant	0	0.63166	2E-87	86.698970004336	""	0.5071	[0.46-0.56] unit decrease	Illumina [18238311] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	CD27 on switched memory B cell	3,657 Sardinian (founder/genetic isolate) ancestry individuals		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-C	rs1883832	0	1883832	5_prime_UTR_variant	0	0.63166	3E-118	117.52287874528	""	0.5853	[0.54-0.63] unit decrease	Illumina [18238311] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-08-05	35835914	Watanabe K	2022-07-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35835914	Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.	Insomnia	593,724 European ancestry cases, 1,771,286 European ancestry controls		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-T	rs1883832	0	1883832	5_prime_UTR_variant	0	NR	8E-10	9.09691001300806	""	0.006	[0.004-0.008] unit increase	Illumina [10713943] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2021-04-27	33686288	Peyrot WJ	2021-03-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33686288	Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS.	Crohn's disease vs rheumatoid arthritis (ordinary least squares (OLS))	5,956 Crohn's disease cases, 8,875 rheumatoid arthritis cases	14,594 Crohn's disease cases, 5,486 rheumatoid arthritis cases	20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-?	rs1883832	0	1883832	5_prime_UTR_variant	0	NR	9E-15	14.0457574905607	""	0.064	NR unit decrease	NR [5890016] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-11-09	36333501	Ishigaki K	2022-11-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/36333501	Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.	Rheumatoid arthritis	22,350 European ancestry cases, 74,823 European ancestry controls		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-C	rs1883832	0	1883832	5_prime_UTR_variant	0	0.7406	3E-12	11.5228787452803	""	1.1092676	[1.07755278805364-1.14191590134881]	Affymetrix, Illumina [20990826] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-11-09	36333501	Ishigaki K	2022-11-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/36333501	Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.	Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive)	17,221 European ancestry cases, 74,823 European ancestry controls, 8,340 East Asian ancestry cases, 162,608 East Asian ancestry controls, 841 African ancestry cases, 1,108 African ancestry controls, 689 South Asian ancestry cases, 1,258 South Asian ancestry controls, 357 Arab ancestry cases, 352 Arab ancestry controls		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-C	rs1883832	0	1883832	5_prime_UTR_variant	0	NR	1E-17	17	""	1.11572	[1.08807759083635-1.14406480491037]	Affymetrix, Illumina [20990826] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-11-09	36333501	Ishigaki K	2022-11-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/36333501	Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.	Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive)	17,221 European ancestry cases, 74,823 European ancestry controls		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-C	rs1883832	0	1883832	5_prime_UTR_variant	0	0.7406	3E-13	12.5228787452803	""	1.1256943	[1.09051338792266-1.16201017697981]	Affymetrix, Illumina [20990826] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-07-29	35470158	Saevarsdottir S	2022-04-25	Ann Rheum Dis	www.ncbi.nlm.nih.gov/pubmed/35470158	Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset.	Rheumatoid arthritis	26,612 European ancestry cases, 869,454 European ancestry controls, 4,701 cases, 125,923 controls		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-T	rs1883832	0	1883832	5_prime_UTR_variant	0	0.25	6E-6	5.22184874961636	""	0.95	""	Affymetrix, Illumina [64000000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-07-29	35470158	Saevarsdottir S	2022-04-25	Ann Rheum Dis	www.ncbi.nlm.nih.gov/pubmed/35470158	Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset.	Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive)	14,551 European ancestry cases, 846,260 European ancestry controls, 3,468 cases, 145,344 controls		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-T	rs1883832	0	1883832	5_prime_UTR_variant	0	0.25	1E-8	8	""	0.92	""	Affymetrix, Illumina [64000000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-11-09	36333501	Ishigaki K	2022-11-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/36333501	Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.	Rheumatoid arthritis	11,025 East Asian ancestry cases, 162,608 East Asian ancestry controls		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-C	rs1883832	0	1883832	5_prime_UTR_variant	0	0.5675	9E-10	9.04575749056067	""	1.1109328	[1.07410592673264-1.14902226975174]	Affymetrix, Illumina [20990826] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44746982	rs1883832	2022-11-09	36333501	Ishigaki K	2022-11-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/36333501	Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.	Rheumatoid arthritis	22,350 European ancestry cases, 74,823 European ancestry controls, 11,025 East Asian ancestry cases, 162,608 East Asian ancestry controls, 999 African ancestry cases, 1,108 African ancestry controls, 986 South Asian ancestry cases, 1,258 South Asian ancestry controls, 511 Arab ancestry cases, 352 Arab ancestry controls		20q13.12	""	CD40	""	""	ENSG00000101017			rs1883832-C	rs1883832	0	1883832	5_prime_UTR_variant	0	NR	4E-21	20.397940008672	""	1.1090457	[1.08539111443412-1.13321599506738]	Affymetrix, Illumina [20990826] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44747947	rs4810485	2010-06-13	20453842	Stahl EA	2010-05-09	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20453842	Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.	Rheumatoid arthritis	5,539 European ancestry cases, 20,169 European ancestry controls	6,768 European ancestry cases, 8,806 European ancestry controls	20q13.12	CD40	CD40	""	""	ENSG00000101017			rs4810485-T	rs4810485	0	4810485	intron_variant	0	0.25	3E-9	8.52287874528034	""	1.18	[1.11-1.25]	Affymetrix, Illumina [~ 2716259] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44747947	rs4810485	2018-04-25	24076602	Beecham AH	2013-11-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/24076602	Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.	Multiple sclerosis	14,498 European ancestry cases, 24,091 European ancestry controls	14,802 European ancestry cases, 26,703 European ancestry controls	20q13.12	CD40	CD40	""	""	ENSG00000101017			rs4810485-A	rs4810485	0	4810485	intron_variant	0	0.25	8E-16	15.0969100130081	""	1.11	""	Illumina [161311]	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44747947	rs4810485	2018-05-08	23143596	Eyre S	2012-12-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23143596	High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.	Rheumatoid arthritis	up to 13,838 European ancestry cases, up to 33,742 European ancestry controls		20q13.12	CD40	CD40	""	""	ENSG00000101017			rs4810485-?	rs4810485	0	4810485	intron_variant	0	NR	2E-7	6.69897000433602	""		""	Illumina [129464] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44747947	rs4810485	2018-05-08	23143596	Eyre S	2012-12-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23143596	High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.	Rheumatoid arthritis (ACPA-positive)	up to 9,585 European ancestry cases, up to 33,742 European ancestry controls		20q13.12	CD40	CD40	""	""	ENSG00000101017			rs4810485-?	rs4810485	0	4810485	intron_variant	0	NR	9E-11	10.0457574905607	""		""	Illumina [129464] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44747947	rs4810485	2008-09-25	18794853	Raychaudhuri S	2008-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18794853	Common variants at CD40 and other loci confer risk of rheumatoid arthritis.	Rheumatoid arthritis	3,393 European ancestry cases, 12,460 European ancestry controls	3,929 European ancestry cases, 5,807 European ancestry controls	20q13.12	CD40	CD40	""	""	ENSG00000101017			rs4810485-G	rs4810485	0	4810485	intron_variant	0	0.75	8E-9	8.09691001300806	""	1.15	[NR]	Affymetrix, Illumina [at least 315971] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44747947	rs4810485	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	IgD- CD27- B cell %B cell	3,657 Sardinian (founder/genetic isolate) ancestry individuals		20q13.12	""	CD40	""	""	ENSG00000101017			rs4810485-G	rs4810485	0	4810485	intron_variant	0	0.63138	7E-50	49.1549019599858	""	0.3898	[0.34-0.44] unit increase	Illumina [18238311] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44747947	rs4810485	2022-02-14	32929287	Orru V	2020-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32929287	Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.	IgD- CD27- B cell %lymphocyte	3,656 Sardinian (founder/genetic isolate) ancestry individuals		20q13.12	""	CD40	""	""	ENSG00000101017			rs4810485-G	rs4810485	0	4810485	intron_variant	0	0.63127	5E-33	32.301029995664	""	0.317	[0.27-0.37] unit increase	Illumina [18238287] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44680853	rs12624433	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Depressive symptoms	1,067,913 European ancestry individuals	228,033 European ancestry individuals	20q13.12	NR	SLC12A5	""	""	ENSG00000124140			rs12624433-A	rs12624433	0	12624433	intron_variant	0	0.257043985058978	2E-11	10.698970004336	""	0.008000939	[0.0057-0.0103] unit increase	NR [NR]	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44680853	rs12624433	2019-03-19	30718901	Howard DM	2019-02-04	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/30718901	Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.	Depression	118,811 European ancestry cases, 327,427 European ancestry controls, 127,552 cases, 233,763 controls	414,055 European ancestry cases, 892,299 European ancestry controls	20q13.12	NR	SLC12A5	""	""	ENSG00000124140			rs12624433-A	rs12624433	0	12624433	intron_variant	0	0.2584	2E-14	13.698970004336	""	1.019	[1.014-1.024]	NR [8098588] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44680853	rs12624433	2021-07-27	33479212	Yao X	2021-01-21	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/33479212	Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders.	Neuropsychiatric disorders	19,099 European ancestry attention deficit hyperactivity disorder cases, 18,381 European ancestry autism spectrum disorder cases, 20,352 European ancestry bipolar disorder cases, 170,756 European ancestry major depressive disorder cases, 33,640 European ancestry schizophrenia cases, 466,420 European ancestry controls		20q13.12	NR	SLC12A5	""	""	ENSG00000124140			rs12624433-A	rs12624433	0	12624433	intron_variant	0	NR	5E-10	9.30102999566398	""	6.219	NR z score increase	NR [NR]	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44680853	rs12624433	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Neuroticism	523,783 European ancestry individuals	59,206 European ancestry individuals	20q13.12	NR	SLC12A5	""	""	ENSG00000124140			rs12624433-A	rs12624433	0	12624433	intron_variant	0	0.257043985058978	2E-11	10.698970004336	""	0.012529465	[0.0089-0.0162] unit increase	NR [NR]	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44680853	rs12624433	2022-11-18	34924174	Mitchell BL	2021-11-02	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/34924174	The Australian Genetics of Depression Study: New Risk Loci and Dissecting Heterogeneity Between Subtypes.	Depression	13,318 European ancestry cases, 12,684 European ancestry controls, 246,363 cases, 561,190 controls		20q13.12	""	SLC12A5	""	""	ENSG00000124140			rs12624433-?	rs12624433	0	12624433	intron_variant	0	NR	2E-9	8.69897000433602	""	0.0232	unit increase	Illumina [7617771] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44680853	rs12624433	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		20q13.12	Intergenic	SLC12A5	""	""	ENSG00000124140			rs12624433-A	rs12624433	0	12624433	intron_variant	0	0.2657	4E-10	9.39794000867204	(MTAG)	0.0127	[0.0088-0.0166] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44680853	rs12624433	2022-09-28	34282934	Fan W	2021-07-20	mSystems	www.ncbi.nlm.nih.gov/pubmed/34282934	Association between Human Genetic Variants and the Vaginal Bacteriome of Pregnant Women.	Vaginal microbiome presence (c_Actinobacteria)	315 Chinese ancestry individuals		20q13.12	""	SLC12A5	""	""	ENSG00000124140			rs12624433-A	rs12624433	0	12624433	intron_variant	0	NR	2E-6	5.69897000433602	""	0.3744	[0.2504-0.5598]	Illumina [492582]	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44688665	rs9074	2022-09-28	34282934	Fan W	2021-07-20	mSystems	www.ncbi.nlm.nih.gov/pubmed/34282934	Association between Human Genetic Variants and the Vaginal Bacteriome of Pregnant Women.	Vaginal microbiome presence (c_Actinobacteria)	315 Chinese ancestry individuals		20q13.12	""	SLC12A5	""	""	ENSG00000124140			rs9074-A	rs9074	0	9074	3_prime_UTR_variant	0	NR	6E-6	5.22184874961636	""	0.4066	[0.275-0.6012]	Illumina [492582]	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44692598	rs13037326	2021-07-27	33479212	Yao X	2021-01-21	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/33479212	Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders.	Major depressive disorder (MTAG)	at least 170,756 European ancestry cases, at least 329,443 European ancestry controls		20q13.12	NR	NCOA5	""	""	ENSG00000124160			rs13037326-T	rs13037326	0	13037326	intron_variant	0	0.2597	2E-12	11.698970004336	""	0.03317893	[0.024-0.042] unit increase	NR [NR]	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44692598	rs13037326	2022-09-28	34282934	Fan W	2021-07-20	mSystems	www.ncbi.nlm.nih.gov/pubmed/34282934	Association between Human Genetic Variants and the Vaginal Bacteriome of Pregnant Women.	Vaginal microbiome presence (c_Actinobacteria)	315 Chinese ancestry individuals		20q13.12	""	NCOA5	""	""	ENSG00000124160			rs13037326-T	rs13037326	0	13037326	intron_variant	0	NR	6E-6	5.22184874961636	""	0.4066	[0.275-0.6012]	Illumina [492582]	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44702120	rs2425752	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Neuroticism	449,484 European ancestry individuals		20q13.12	NR	NCOA5	""	""	ENSG00000124160			rs2425752-T	rs2425752	0	2425752	intron_variant	0	NR	5E-13	12.301029995664	""	7.212	z score increase	Affymetrix [10847151] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44702120	rs2425752	2019-09-20	31407831	Din L	2019-08-13	Genet Epidemiol	www.ncbi.nlm.nih.gov/pubmed/31407831	Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes.	Diffuse large B-cell lymphoma or multiple sclerosis	3,617 European ancestry diffuse large B-cell lymphoma cases, 9,772 European ancestry multiple sclerosis cases, 24,813 European ancestry controls		20q13.12	NCOA5	NCOA5	""	""	ENSG00000124160			rs2425752-?	rs2425752	0	2425752	intron_variant	0	NR	5E-9	8.30102999566398	""	1.098901	""	Illumina [~ 460000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44702120	rs2425752	2019-09-20	31407831	Din L	2019-08-13	Genet Epidemiol	www.ncbi.nlm.nih.gov/pubmed/31407831	Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes.	Follicular lymphoma or multiple sclerosis	2,686 European ancestry follicular lymphoma cases, 9,772 European ancestry multiple sclerosis cases, 25,256 European ancestry controls		20q13.12	NCOA5	NCOA5	""	""	ENSG00000124160			rs2425752-?	rs2425752	0	2425752	intron_variant	0	NR	1E-7	7	""	1.0899183	""	Illumina [~ 460000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44702120	rs2425752	2019-09-20	31407831	Din L	2019-08-13	Genet Epidemiol	www.ncbi.nlm.nih.gov/pubmed/31407831	Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes.	Marginal zone lymphoma or multiple sclerosis	741 European ancestry marginal zone lymphoma cases, 9,772 European ancestry multiple sclerosis cases, 23,367 European ancestry controls		20q13.12	NCOA5	NCOA5	""	""	ENSG00000124160			rs2425752-?	rs2425752	0	2425752	intron_variant	0	NR	1E-7	7	""	1.0957704	""	Illumina [~ 460000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44702120	rs2425752	2012-10-24	21833088	Sawcer S	2011-08-11	Nature	www.ncbi.nlm.nih.gov/pubmed/21833088	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	Multiple sclerosis	9,772 European ancestry cases, 16,849 European ancestry controls	4,218 European ancestry cases, 7,296 European ancestry controls	20q13.12	NCOA5, CD40	NCOA5	""	""	ENSG00000124160			rs2425752-A	rs2425752	0	2425752	intron_variant	0	NR	5E-10	9.30102999566398	""	1.11	[1.1-1.13]	Illumina [465434]	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44702120	rs2425752	2019-02-08	30194254	Sud A	2018-09-07	Blood	www.ncbi.nlm.nih.gov/pubmed/30194254	Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma.	Hodgkin's lymphoma	5,325 European ancestry cases, 22,425 European ancestry controls		20q13.12	NCOA5, CD40	NCOA5	""	""	ENSG00000124160			rs2425752-T	rs2425752	0	2425752	intron_variant	0	0.23	2E-8	7.69897000433602	""	1.15	[1.10-1.21]	Illumina [> 10000000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44702120	rs2425752	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Neuroticism	approximately 372,000 European ancestry individuals		20q13.12	""	NCOA5	""	""	ENSG00000124160			rs2425752-?	rs2425752	0	2425752	intron_variant	0	NR	2E-9	8.69897000433602	""		""	NR [~ 8900000] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44702120	rs2425752	2022-09-28	34282934	Fan W	2021-07-20	mSystems	www.ncbi.nlm.nih.gov/pubmed/34282934	Association between Human Genetic Variants and the Vaginal Bacteriome of Pregnant Women.	Vaginal microbiome presence (c_Actinobacteria)	315 Chinese ancestry individuals		20q13.12	""	NCOA5	""	""	ENSG00000124160			rs2425752-T	rs2425752	0	2425752	intron_variant	0	NR	6E-6	5.22184874961636	""	0.4066	[0.275-0.6012]	Illumina [492582]	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44721656	rs4578918	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Depressed affect	357,957 European ancestry individuals		20q13.12	NR	NCOA5 - RPL13P2	ENSG00000124160	ENSG00000213820	""	3055	6501	rs4578918-T	rs4578918	0	4578918	intergenic_variant	1	NR	1E-11	11	""	0.01792	[0.013-0.023] unit increase	Affymetrix [10847151] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44721656	rs4578918	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Neurociticism	380,506 European ancestry individuals		20q13.12	PLTP	NCOA5 - RPL13P2	ENSG00000124160	ENSG00000213820	""	3055	6501	rs4578918-T	rs4578918	0	4578918	intergenic_variant	1	0.256817	1E-10	10	""	6.44	z score increase	NR [10847151] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44721656	rs4578918	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Experiencing mood swings	373,733 European ancestry individuals		20q13.12	PLTP	NCOA5 - RPL13P2	ENSG00000124160	ENSG00000213820	""	3055	6501	rs4578918-T	rs4578918	0	4578918	intergenic_variant	1	0.256817	1E-9	9	""	6.06	z score increase	NR [10847151] (imputed)	N
rs6065926	20	44735854	G	A	0.255467	3.00883311521e-09	-0.00611366034001	0.00103077747484	199	20	44724305	rs6131010	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Well-being spectrum (multivariate analysis)	2,083,151 European ancestry individuals	287,239 European ancestry individuals	20q13.12	NR	NCOA5 - RPL13P2	ENSG00000124160	ENSG00000213820	""	5704	3852	rs6131010-G	rs6131010	0	6131010	upstream_gene_variant	1	0.736760557817369	1E-11	11	""	0.007101281	[0.0051-0.0091] unit decrease	NR [NR]	N
rs6706856	2	16615530	C	T	0.207753	2.20539505832e-08	0.00590474637542	0.00105534907781	21	2	16626887	rs4832443	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Platelet count	350,474 European ancestry individuals, 148,623 East Asian ancestry individuals		2p24.3	""	GACAT3 - CYRIA	ENSG00000236289	ENSG00000197872	""	358418	103840	rs4832443-T	rs4832443	0	4832443	intergenic_variant	1	NR	5E-8	7.30102999566398	""	0.0142	[0.0091-0.0193] unit increase	Affymetrix, Illumina [20538505] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71544954	rs4852778	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	Reaction time	330,069 European ancestry individuals		2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs4852778-?	rs4852778	0	4852778	intron_variant	0	NR	4E-8	7.39794000867204	""	0.0096549	[0.0062-0.0131] unit decrease	Affymetrix [805426] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71539301	rs4852252	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs4852252-?	rs4852252	0	4852252	intron_variant	0	NR	6E-14	13.2218487496164	""		""	NR [6307410] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71539301	rs4852252	2022-11-18	34924174	Mitchell BL	2021-11-02	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/34924174	The Australian Genetics of Depression Study: New Risk Loci and Dissecting Heterogeneity Between Subtypes.	Depression	13,318 European ancestry cases, 12,684 European ancestry controls, 246,363 cases, 561,190 controls		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs4852252-?	rs4852252	0	4852252	intron_variant	0	NR	3E-8	7.52287874528034	""	0.0034	unit increase	Illumina [7617771] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71618599	rs12478953	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Mean corpuscular volume	408,112 British individuals		2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs12478953-C	rs12478953	0	12478953	intron_variant	0	0.661263	1E-15	15	""	0.018222	[0.014-0.022] unit increase	Affymetrix [93095623] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71539301	rs4852252	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		2p13.2		ZNF638	""	""	ENSG00000075292			rs4852252-T	rs4852252	0	4852252	intron_variant	0	NR	6E-10	9.22184874961636	""	6.191	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71534161	rs4852777	2022-04-26	35399580	Fernandez-Rhodes L	2022-03-11	HGG Adv	www.ncbi.nlm.nih.gov/pubmed/35399580	Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium.	Height	59,771 Hispanic or Latin American individuals	8,110 Hispanic or Latin American individuals	2p13.2	""	ZNF638	""	""	ENSG00000075292			rs4852777-C	rs4852777	0	4852777	intron_variant	0	0.5976	2E-9	8.69897000433602	""	0.0353	[0.024-0.047] unit decrease	Affymetrix, Illumina [8927938] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71572917	rs6746731	2017-07-18	28530673	Sniekers S	2017-05-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28530673	Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence.	Intelligence	up to 58,799 European ancestry adults, up to 19,509 European ancestry children		2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs6746731-T	rs6746731	0	6746731	intron_variant	0	0.4287	5E-8	7.30102999566398	""	5.456	z score decrease	Affymetrix, Illumina [12104294] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71618599	rs12478953	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Mean corpuscular hemoglobin	486,823 European ancestry individuals		2p13.2	NR	ZNF638	""	""	ENSG00000075292			rs12478953-C	rs12478953	0	12478953	intron_variant	0	0.661043	4E-11	10.397940008672	""	0.013357	[0.0094-0.0173] SD unit increase	Affymetrix, Illumina [50266654] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71539301	rs4852252	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		2p13.2	Intergenic	ZNF638	""	""	ENSG00000075292			rs4852252-T	rs4852252	0	4852252	intron_variant	0	0.4338	6E-10	9.22184874961636	(MTAG)	0.0143	[0.0098-0.0188] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71572917	rs6746731	2017-07-18	28530673	Sniekers S	2017-05-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28530673	Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence.	Intelligence	up to 58,799 European ancestry adults, up to 19,509 European ancestry children		2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs6746731-T	rs6746731	0	6746731	intron_variant	0	0.4287	4E-6	5.39794000867204	(Adults)	4.591	z score decrease	Affymetrix, Illumina [12104294] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71584485	rs7568069	2022-04-26	35399580	Fernandez-Rhodes L	2022-03-11	HGG Adv	www.ncbi.nlm.nih.gov/pubmed/35399580	Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium.	Height	59,771 Hispanic or Latin American individuals	8,110 Hispanic or Latin American individuals	2p13.2	""	ZNF638	""	""	ENSG00000075292			rs7568069-A	rs7568069	0	7568069	intron_variant	0	0.5846	2E-8	7.69897000433602	""	0.0327	[0.021-0.044] unit decrease	Affymetrix, Illumina [8927938] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71583924	rs6726122	2021-08-24	34021172	Christakoudi S	2021-05-21	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/34021172	GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer.	Hip circumference adjusted for BMI	219,872 British ancestry women		2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs6726122-A	rs6726122	0	6726122	intron_variant	0	NR	5E-12	11.301029995664	""	0.0196257	[0.014-0.025] unit increase	Affymetrix [321016] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71631345	rs4852256	2021-06-29	32895543	de la Fuente J	2020-09-07	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/32895543	A general dimension of genetic sharing across diverse cognitive traits inferred from molecular data.	Reaction time	330,024 British ancestry individuals		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs4852256-?	rs4852256	0	4852256	intron_variant	0	NR	4E-8	7.39794000867204	""		""	NR [7857346] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71676366	rs4241246	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	Reaction time	330,069 European ancestry individuals		2p13.2	NR	ZNF638 - DYSF	ENSG00000075292	ENSG00000135636	""	14167	4325	rs4241246-?	rs4241246	0	4241246	intergenic_variant	1	NR	5E-8	7.30102999566398	""	0.0095654	[0.0061-0.013] unit decrease	Affymetrix [805426] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71658017	rs6546692	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Aspartate aminotransferase levels	342,990 European ancestry individuals, 150,068 East Asian ancestry individuals		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs6546692-A	rs6546692	0	6546692	intron_variant	0	NR	7E-15	14.1549019599857	""	0.0162	[0.012-0.02] unit decrease	Affymetrix, Illumina [20538469] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71647809	rs4852785	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Mean reticulocyte volume	408,112 British individuals		2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs4852785-A	rs4852785	0	4852785	intron_variant	0	0.572886	1E-18	18	""	0.019943275	[0.016-0.024] unit increase	Affymetrix [93095623] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71658017	rs6546692	2021-08-24	34021172	Christakoudi S	2021-05-21	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/34021172	GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer.	Hip circumference adjusted for BMI	186,825 British ancestry men		2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs6546692-A	rs6546692	0	6546692	intron_variant	0	NR	4E-13	12.397940008672	""	0.0224138	[0.016-0.028] unit increase	Affymetrix [323123] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71534617	rs4470366	2021-01-13	33414549	Demange PA	2021-01-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33414549	Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.	Cognitive aspects of educational attainment	257,700 European ancestry individuals		2p13.2	NR	ZNF638	""	""	ENSG00000075292			rs4470366-T	rs4470366	0	4470366	intron_variant	0	0.436382	5E-10	9.30102999566398	""	0.039447937	[0.027-0.052] unit decrease	Affymetrix, Illumina, Perlegen [7305956] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71534161	rs4852777	2022-08-05	35831902	Chiou JS	2022-07-13	BMC Med	www.ncbi.nlm.nih.gov/pubmed/35831902	Your height affects your health: genetic determinants and health-related outcomes in Taiwan.	Height	67,452 Han Chinese ancestry individuals		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs4852777-G	rs4852777	0	4852777	intron_variant	0	NR	4E-16	15.397940008672	""	0.044	[0.034-0.055] unit increase	Affymetrix [NR] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71594534	rs10445946	2018-10-18	30048462	Kim SK	2018-07-26	PLoS One	www.ncbi.nlm.nih.gov/pubmed/30048462	Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.	Heel bone mineral density	394,929 European ancestry individuals		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs10445946-?	rs10445946	0	10445946	intron_variant	0	NR	2E-9	8.69897000433602	""	0.0121493	[0.0081-0.0162] unit decrease	Affymetrix [20259828] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71534617	rs4470366	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs4470366-A	rs4470366	0	4470366	intron_variant	0	0.5842	1E-9	9	""	0.00647627	[0.0044-0.0086] unit increase	Illumina [10675380] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71618599	rs12478953	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Mean corpuscular hemoglobin	630,125 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals		2p13.2	NR	ZNF638	""	""	ENSG00000075292			rs12478953-C	rs12478953	0	12478953	intron_variant	0	0.622374	1E-10	10	""		""	Affymetrix, Illumina [20825802] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71609073	rs6745907	2019-02-06	29520040	Coleman JRI	2018-03-08	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29520040	Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals.	Extremely high intelligence	1,247 European ancestry cases, 86,493 European ancestry controls		2p13.2	DYSF, PAIP2B, ZNF638	ZNF638	""	""	ENSG00000075292			rs6745907-A	rs6745907	0	6745907	intron_variant	0	0.433	6E-9	8.22184874961636	""	5.82	NR z-score decrease	Illumina [up to 12595966] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71534617	rs4470366	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance	257,841 European ancestry individuals		2p13.2	Intergenic	ZNF638	""	""	ENSG00000075292			rs4470366-A	rs4470366	0	4470366	intron_variant	0	0.5833	4E-10	9.39794000867204	""	0.0182	[0.013-0.024] unit increase	Affymetrix, Illumina [10100000] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71534617	rs4470366	2019-01-28	30598549	Morris JA	2018-12-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30598549	An atlas of genetic influences on osteoporosis in humans and mice.	Heel bone mineral density	426,824 British ancestry individuals		2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs4470366-T	rs4470366	0	4470366	intron_variant	0	0.416638	2E-11	10.698970004336	""	0.0124535	[0.0088-0.0161] unit decrease	NR [13737936] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71562503	rs17743415	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Mean corpuscular volume	696,882 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals		2p13.2	NR	ZNF638	""	""	ENSG00000075292			rs17743415-C	rs17743415	0	17743415	intron_variant	0	0.490464	2E-19	18.698970004336	""		""	Affymetrix, Illumina [24246363] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71539301	rs4852252	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		2p13.2	NR	ZNF638	""	""	ENSG00000075292			rs4852252-T	rs4852252	0	4852252	intron_variant	0	NR	4E-14	13.397940008672	""	7.566	z-score decrease	Affymetrix, Illumina [9295118] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71562503	rs17743415	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Mean corpuscular volume	544,127 European ancestry individuals		2p13.2	NR	ZNF638	""	""	ENSG00000075292			rs17743415-C	rs17743415	0	17743415	intron_variant	0	0.565582	3E-18	17.5228787452803	""	0.01593	[0.012-0.02] SD unit increase	Affymetrix, Illumina [50615308] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71584485	rs7568069	2015-09-24	25282103	Wood AR	2014-10-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/25282103	Defining the role of common variation in the genomic and biological architecture of adult human height.	Height	253,288 European ancestry individuals	80,067 European ancestry individuals	2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs7568069-A	rs7568069	0	7568069	intron_variant	0	0.578	3E-13	12.5228787452803	""	0.022	[0.016-0.028] unit decrease	Affymetrix, Illumina, Perlegen [2550858] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71630041	rs7578166	2018-10-18	30048462	Kim SK	2018-07-26	PLoS One	www.ncbi.nlm.nih.gov/pubmed/30048462	Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture.	Heel bone mineral density	394,929 European ancestry individuals		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs7578166-?	rs7578166	0	7578166	intron_variant	0	NR	3E-9	8.52287874528034	""	0.0123592	[0.0082-0.0165] unit decrease	Affymetrix [20259828] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71568206	rs1990774	2018-01-12	29186694	Lam M	2017-11-28	Cell Rep	www.ncbi.nlm.nih.gov/pubmed/29186694	Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.	Cognitive ability	107,207 European ancestry individuals		2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs1990774-?	rs1990774	0	1990774	intron_variant	0	NR	2E-8	7.69897000433602	""	5.629	z score decrease	Affymetrix, Illumina [7357080] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71534498	rs2419075	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs2419075-?	rs2419075	0	2419075	intron_variant	0	NR	3E-8	7.52287874528034	""		""	NR [6307410] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71534161	rs4852777	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Lymphocyte count	408,112 British individuals		2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs4852777-C	rs4852777	0	4852777	intron_variant	0	0.595185	1E-9	9	""	0.013558241	[0.0092-0.018] unit increase	Affymetrix [93095623] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71562503	rs17743415	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Heel bone mineral density	approximately 446,000 European ancestry individuals		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs17743415-?	rs17743415	0	17743415	intron_variant	0	NR	4E-14	13.397940008672	""		""	NR [~ 8900000] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71618599	rs12478953	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Mean corpuscular hemoglobin	approximately 443,000 European ancestry individuals		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs12478953-?	rs12478953	0	12478953	intron_variant	0	NR	2E-9	8.69897000433602	""		""	NR [~ 8900000] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71614443	rs6717013	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Mean corpuscular hemoglobin	350,472 European ancestry individuals, 128,028 East Asian ancestry individuals		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs6717013-A	rs6717013	0	6717013	intron_variant	0	NR	3E-8	7.52287874528034	""	0.0114	[0.0073-0.0155] unit decrease	Affymetrix, Illumina [20535878] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71584485	rs7568069	2019-07-02	31217584	Wojcik GL	2019-06-19	Nature	www.ncbi.nlm.nih.gov/pubmed/31217584	Genetic analyses of diverse populations improves discovery for complex traits.	Height	17,286 African American individuals, 22,192 Hispanic/Latino individuals, 4,680 Asian ancestry individuals, 3,939 Native Hawaiian ancestry individuals, 647 Native American ancestry individuals, 1,052 individuals		2p13.2	NR	ZNF638	""	""	ENSG00000075292			rs7568069-?	rs7568069	0	7568069	intron_variant	0	NR	9E-10	9.04575749056067	""	0.03647608	[0.025-0.048] unit decrease	Illumina [34656550] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71534498	rs2419075	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		2p13.2	NR	ZNF638	""	""	ENSG00000075292			rs2419075-T	rs2419075	0	2419075	intron_variant	0	NR	2E-8	7.69897000433602	""	5.618	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71630041	rs7578166	2018-09-20	28869591	Kemp JP	2017-09-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28869591	Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis.	Heel bone mineral density	76,067 European ancestry women, 66,420 European ancestry men		2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs7578166-A	rs7578166	0	7578166	intron_variant	0	0.389101	8E-7	6.09691001300806	(women)	0.0227096	[0.014-0.032] unit decrease	NR [17166351] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71534161	rs4852777	2019-05-21	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Height	approximately 458,000 European ancestry individuals		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs4852777-?	rs4852777	0	4852777	intron_variant	0	NR	1E-86	86	""		""	NR [~ 8900000] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71583924	rs6726122	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Lymphocyte count	349,856 European ancestry individuals, 95,717 East Asian ancestry individuals		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs6726122-T	rs6726122	0	6726122	intron_variant	0	NR	2E-11	10.698970004336	""	0.0161	[0.011-0.021] unit increase	Affymetrix, Illumina [20531022] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71613914	rs7557781	2019-09-04	31374203	Lam M	2019-08-01	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/31374203	Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy)	328,917 individuals with educational attainment measurements, 107,207 individuals with cognitive ability measurements, 77,096 European ancestry schizophrenia cases, 43,456 European ancestry controls		2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs7557781-?	rs7557781	0	7557781	intron_variant	0	NR	5E-12	11.301029995664	""	0.013778182	[0.0099-0.0177] unit decrease	NR [7306098]	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71678520	rs4852257	2020-11-04	33097823	Pei YF	2020-10-23	Commun Biol	www.ncbi.nlm.nih.gov/pubmed/33097823	The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study.	Appendicular lean mass	450,243 European ancestry individuals		2p13.2	DYSF	ZNF638 - DYSF	ENSG00000075292	ENSG00000135636	""	16321	2171	rs4852257-T	rs4852257	0	4852257	intergenic_variant	1	0.4237	6E-34	33.2218487496164	""	0.0231	[0.019-0.027] unit increase	Affymetrix [18391927] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71533300	rs6731420	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		2p13.2	NR	ZNF638	""	""	ENSG00000075292			rs6731420-T	rs6731420	0	6731420	intron_variant	0	NR	2E-8	7.69897000433602	""	0.016438717	[0.011-0.022] unit decrease	Affymetrix [NR]	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71562503	rs17743415	2021-02-19	33547301	Chen VL	2021-02-05	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/33547301	Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology.	Aspartate aminotransferase levels	389,565 European ancestry individuals	134,182 East Asian ancestry individuals	2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs17743415-C	rs17743415	0	17743415	intron_variant	0	0.57	2E-10	9.69897000433602	""	6.36	z-score increase	Affymetrix [4314223] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71630041	rs7578166	2018-09-20	28869591	Kemp JP	2017-09-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28869591	Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis.	Heel bone mineral density	76,067 European ancestry women, 66,420 European ancestry men		2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs7578166-A	rs7578166	0	7578166	intron_variant	0	0.388582	2E-10	9.69897000433602	""	0.0224212	[0.016-0.029] unit decrease	NR [17166351] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71534161	rs4852777	2019-07-17	28552196	Tachmazidou I	2017-06-01	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/28552196	Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.	Hip circumference adjusted for BMI	1,247 whole genome sequenced European ancestry individuals, 3,052 whole genome sequenced individuals, 29,518 European ancestry individuals, 400 Carlantino (founder/genetic isolate) individuals, 831 Friuli Venezia Giulia (founder/genetic isolate) individuals, 998 Mylopotamos (founder/genetic isolate) individuals, 871 Pomak (founder/genetic isolate) individuals	205,905 European ancestry individuals	2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs4852777-C	rs4852777	0	4852777	intron_variant	0	0.6008	2E-7	6.69897000433602	""	0.0486	[0.03-0.067] unit decrease	Affymetrix, Illumina, Perlegen [15844966] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71678520	rs4852257	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Serum total protein level	314,921 European ancestry individuals, 133,321 East Asian ancestry individuals		2p13.2	""	ZNF638 - DYSF	ENSG00000075292	ENSG00000135636	""	16321	2171	rs4852257-G	rs4852257	0	4852257	intergenic_variant	1	NR	8E-9	8.09691001300806	""	0.0127	[0.0084-0.017] unit increase	Affymetrix, Illumina [20536782] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71620111	rs4852780	2019-03-07	30578418	Giri A	2018-12-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30578418	Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.	Pulse pressure	365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals	299,024 European ancestry individuals, 17,277 individuals	2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs4852780-T	rs4852780	0	4852780	intron_variant	0	0.4262	2E-9	8.69897000433602	""	0.1526	[0.1-0.2] mmHg increase	Affymetrix [NR] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71584201	rs56408212	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Weight	360,116 European ancestry individuals, 165,419 East Asian ancestry individuals		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs56408212-T	rs56408212	0	56408212	intron_variant	0	NR	4E-11	10.397940008672	""	0.0114	[0.0081-0.0147] unit decrease	Affymetrix, Illumina [20539548] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71614443	rs6717013	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Mean corpuscular volume	350,473 European ancestry individuals, 129,832 East Asian ancestry individuals		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs6717013-A	rs6717013	0	6717013	intron_variant	0	NR	5E-12	11.301029995664	""	0.0141	[0.01-0.018] unit decrease	Affymetrix, Illumina [20535844] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71584201	rs56408212	2019-02-08	30593698	Hubel C	2018-12-28	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/30593698	Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.	Fat-free mass	70,700 European ancestry female individuals, 85,261 European ancestry male individuals		2p13.2	NR	ZNF638	""	""	ENSG00000075292			rs56408212-?	rs56408212	0	56408212	intron_variant	0	NR	3E-12	11.5228787452803	""	0.15542	[0.11-0.2] unit decrease	Affymetrix [7794483] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71618599	rs12478953	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Mean spheric corpuscular volume	408,112 British individuals		2p13.2	ZNF638	ZNF638	""	""	ENSG00000075292			rs12478953-C	rs12478953	0	12478953	intron_variant	0	0.661128	2E-21	20.698970004336	""	0.022361679	[0.018-0.027] unit increase	Affymetrix [93095623] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71584201	rs56408212	2019-02-08	30593698	Hubel C	2018-12-28	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/30593698	Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.	Fat-free mass	70,700 European ancestry female individuals, 85,261 European ancestry male individuals		2p13.2	NR	ZNF638	""	""	ENSG00000075292			rs56408212-?	rs56408212	0	56408212	intron_variant	0	NR	5E-8	7.30102999566398	(male)	0.19204	[0.12-0.26] unit decrease	Affymetrix [7794483] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71618599	rs12478953	2021-11-12	34104963	Thompson A	2021-06-08	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/34104963	Assessing the impact of alcohol consumption on the genetic contribution to mean corpuscular volume.	Mean corpuscular volume	362,595 British ancestry individuals		2p13.2	""	ZNF638	""	""	ENSG00000075292			rs12478953-T	rs12478953	0	12478953	intron_variant	0	0.339	2E-10	9.69897000433602	""	0.07	[-0.1--0.05] % decrease	Affymetrix [NR] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71678520	rs4852257	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Pulse pressure	360,863 European ancestry individuals, 145,445 East Asian ancestry individuals		2p13.2	""	ZNF638 - DYSF	ENSG00000075292	ENSG00000135636	""	16321	2171	rs4852257-G	rs4852257	0	4852257	intergenic_variant	1	NR	1E-8	8	""	0.0109	[0.0072-0.0146] unit decrease	Affymetrix, Illumina [20537391] (imputed)	N
rs6731420	2	71533300	C	T	0.445328	1.48223555786e-10	-0.00613352941775	0.000957288133051	29	2	71529331	rs7605066	2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals		2p13.2	PAIP2B, ZNF638	ZNF638	""	""	ENSG00000075292			rs7605066-C	rs7605066	0	7605066	intron_variant	0	""	6E-9	8.22184874961636	""	0.149	unit increase	Affymetrix [at least 2696785] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56715363	rs4681994	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		3p14.3	NR	TASOR	""	""	ENSG00000163946			rs4681994-?	rs4681994	0	4681994	intron_variant	0	NR	1E-6	6	""	4.864	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56586371	rs7653344	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		3p14.3	Intergenic	ERC2 - CCDC66	ENSG00000187672	ENSG00000180376	""	83876	4818	rs7653344-A	rs7653344	0	7653344	intergenic_variant	1	0.4629	5E-14	13.301029995664	(MTAG)	0.0124	[0.0091-0.0157] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56735180	rs6773931	2011-11-08	21998595	N'Diaye A	2011-10-06	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21998595	Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.	Height	20,427 African ancestry individuals	Up to 16,436 African American individuals	3p14.3	intergenic	TASOR - ARHGEF3	ENSG00000163946	ENSG00000163947	""	17887	26266	rs6773931-A	rs6773931	0	6773931	intergenic_variant	1	0.80	8E-8	7.09691001300806	""	0.053	[0.033-0.073] unit decrease	Affymetrix, Illumina [3310998] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56695060	rs7619465	2021-08-24	34021172	Christakoudi S	2021-05-21	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/34021172	GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer.	Waist circumference adjusted for body mass index	186,825 British ancestry men		3p14.3	FAM208A	TASOR	""	""	ENSG00000163946			rs7619465-A	rs7619465	0	7619465	intron_variant	0	NR	5E-13	12.301029995664	""	0.0223482	[0.016-0.028] unit decrease	Affymetrix [321114] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56570907	rs7625428	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		3p14.3	Intergenic	ERC2 - CCDC66	ENSG00000187672	ENSG00000180376	""	68412	20282	rs7625428-T	rs7625428	0	7625428	intergenic_variant	1	0.6036	5E-14	13.301029995664	(MTAG)	0.0101	[0.0076-0.0126] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56692321	rs4681725	2022-04-27	35213538	Richardson TG	2022-02-25	PLoS Biol	www.ncbi.nlm.nih.gov/pubmed/35213538	Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation.	Phospholipids to total lipids ratio in very small VLDL	115,082 European ancestry individuals		3p14.3	""	TASOR	""	""	ENSG00000163946			rs4681725-T	rs4681725	0	4681725	intron_variant	0	0.584518	2E-8	7.69897000433602	""	0.02315	[0.015-0.031] unit increase	NR [11722792] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56576175	rs2172122	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		3p14.3	""	ERC2 - CCDC66	ENSG00000187672	ENSG00000180376	""	73680	15014	rs2172122-C	rs2172122	0	2172122	intergenic_variant	1	0.361	2E-17	16.698970004336	""	0.00924516	[0.0071-0.0114] unit decrease	Illumina [10675380] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56686329	rs6762851	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Height	360,388 European ancestry individuals, 165,056 East Asian ancestry individuals		3p14.3	""	TASOR	""	""	ENSG00000163946			rs6762851-C	rs6762851	0	6762851	intron_variant	0	NR	3E-35	34.5228787452803	""	0.0174	[0.015-0.02] unit decrease	Affymetrix, Illumina [20538915] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56563340	rs6445797	2015-06-12	25317112	Oh S	2014-09-30	Genomics Inform	www.ncbi.nlm.nih.gov/pubmed/25317112	Epidemiological and genome-wide association study of gastritis or gastric ulcer in korean populations.	Gastritis	977 Korean ancestry female cases, 3,622 Korean ancestry female controls, 804 Korean ancestry male cases, 3,335 Korean ancestry male controls		3p14.3	intergenic	ERC2 - CCDC66	ENSG00000187672	ENSG00000180376	""	60845	27849	rs6445797-C	rs6445797	0	6445797	intergenic_variant	1	NR	2E-6	5.69897000433602	(Females)	1.402	[NR]	NR [349184]	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56692321	rs4681725	2022-04-27	35213538	Richardson TG	2022-02-25	PLoS Biol	www.ncbi.nlm.nih.gov/pubmed/35213538	Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation.	Total concentration of lipoprotein particles	115,082 European ancestry individuals		3p14.3	""	TASOR	""	""	ENSG00000163946			rs4681725-T	rs4681725	0	4681725	intron_variant	0	0.584518	3E-8	7.52287874528034	""	0.0218547	[0.014-0.03] unit decrease	NR [11722792] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56686329	rs6762851	2019-02-08	30593698	Hubel C	2018-12-28	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/30593698	Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.	Fat-free mass	70,700 European ancestry female individuals, 85,261 European ancestry male individuals		3p14.3	NR	TASOR	""	""	ENSG00000163946			rs6762851-?	rs6762851	0	6762851	intron_variant	0	NR	2E-7	6.69897000433602	(male)	0.19057	[0.12-0.26] unit decrease	Affymetrix [7794483] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56667682	rs9835332	2012-10-24	20881960	Lango Allen H	2010-09-29	Nature	www.ncbi.nlm.nih.gov/pubmed/20881960	Hundreds of variants clustered in genomic loci and biological pathways affect human height.	Height	133,653 European ancestry individuals	50,074 European ancestry individuals	3p14.3	C3orf63	TASOR	""	""	ENSG00000163946			rs9835332-C	rs9835332	0	9835332	missense_variant	0	0.46	5E-13	12.301029995664	""	0.026	[NR] unit decrease	Affymetrix, Illumina [2834208] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56686329	rs6762851	2022-10-24	36050321	Young WJ	2022-09-01	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/36050321	Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways.	JT interval	212,199 European ancestry individuals		3p14.3	""	TASOR	""	""	ENSG00000163946			rs6762851-T	rs6762851	0	6762851	intron_variant	0	0.6465	5E-14	13.301029995664	""	0.0244	[0.018-0.031] unit decrease	Affymetrix, Illumina [NR] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56692321	rs4681725	2021-07-01	33713608	Graff M	2021-03-05	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/33713608	Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.	Height	16,021 African ancestry men	2,915 African ancestry men, up to 253,288 European ancestry men	3p14.3	FAM208A	TASOR	""	""	ENSG00000163946			rs4681725-T	rs4681725	0	4681725	intron_variant	0	0.227	2E-9	8.69897000433602	(AA)	0.077	[0.052-0.102] unit increase	Affymetrix, Illumina [16055004] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56586371	rs7653344	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability	564,698 European ancestry individuals		3p14.3	Intergenic	ERC2 - CCDC66	ENSG00000187672	ENSG00000180376	""	83876	4818	rs7653344-A	rs7653344	0	7653344	intergenic_variant	1	0.4628	1E-9	9	""	0.0119	[0.008-0.0158] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56692321	rs4681725	2021-07-01	33713608	Graff M	2021-03-05	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/33713608	Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.	Height	41,389 African ancestry individuals	11,364 African ancestry individuals, 253,288 European ancestry individuals	3p14.3	FAM208A	TASOR	""	""	ENSG00000163946			rs4681725-T	rs4681725	0	4681725	intron_variant	0	""	2E-26	25.698970004336	""		""	Affymetrix, Illumina [17972582] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56667682	rs9835332	2015-09-24	25282103	Wood AR	2014-10-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/25282103	Defining the role of common variation in the genomic and biological architecture of adult human height.	Height	253,288 European ancestry individuals	80,067 European ancestry individuals	3p14.3	C3orf63	TASOR	""	""	ENSG00000163946			rs9835332-C	rs9835332	0	9835332	missense_variant	0	0.46	4E-22	21.397940008672	""	0.028	[0.022-0.034] unit decrease	Affymetrix, Illumina, Perlegen [2550858] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56570907	rs7625428	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		3p14.3	""	ERC2 - CCDC66	ENSG00000187672	ENSG00000180376	""	68412	20282	rs7625428-T	rs7625428	0	7625428	intergenic_variant	1	0.6036	1E-11	11	""	0.0098	[0.0071-0.0125] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56586371	rs7653344	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		3p14.3	Intergenic	ERC2 - CCDC66	ENSG00000187672	ENSG00000180376	""	83876	4818	rs7653344-A	rs7653344	0	7653344	intergenic_variant	1	0.4628	6E-13	12.2218487496164	(MTAG)	0.0129	[0.0094-0.0164] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56686329	rs6762851	2019-02-08	30593698	Hubel C	2018-12-28	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/30593698	Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.	Fat-free mass	70,700 European ancestry female individuals, 85,261 European ancestry male individuals		3p14.3	NR	TASOR	""	""	ENSG00000163946			rs6762851-?	rs6762851	0	6762851	intron_variant	0	NR	1E-10	10	""	0.1488	[0.1-0.19] unit decrease	Affymetrix [7794483] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56586371	rs7653344	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		3p14.3	Intergenic	ERC2 - CCDC66	ENSG00000187672	ENSG00000180376	""	83876	4818	rs7653344-A	rs7653344	0	7653344	intergenic_variant	1	0.4664	3E-12	11.5228787452803	(MTAG)	0.016	[0.011-0.021] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56664852	rs6445804	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Eczema	approximately 459,000 European ancestry individuals		3p14.3	""	TASOR	""	""	ENSG00000163946			rs6445804-?	rs6445804	0	6445804	intron_variant	0	NR	1E-8	8	""		""	NR [~ 8900000] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56620557	rs767602469	2021-08-24	34021172	Christakoudi S	2021-05-21	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/34021172	GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer.	Hip circumference adjusted for BMI	219,872 British ancestry women		3p14.3	CCDC66	CCDC66	""	""	ENSG00000180376			rs767602469-CA	rs767602469	0	767602469	intron_variant	0	NR	5E-9	8.30102999566398	""	0.016677	[0.011-0.022] unit decrease	Affymetrix [321016] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56686329	rs6762851	2020-11-04	33097823	Pei YF	2020-10-23	Commun Biol	www.ncbi.nlm.nih.gov/pubmed/33097823	The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study.	Appendicular lean mass	450,243 European ancestry individuals		3p14.3	TASOR	TASOR	""	""	ENSG00000163946			rs6762851-T	rs6762851	0	6762851	intron_variant	0	0.6427	1E-28	28	""	0.0218	[0.018-0.026] unit increase	Affymetrix [18391927] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56692321	rs4681725	2021-07-01	33713608	Graff M	2021-03-05	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/33713608	Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.	Height	41,389 African ancestry individuals	11,364 African ancestry individuals, 253,288 European ancestry individuals	3p14.3	FAM208A	TASOR	""	""	ENSG00000163946			rs4681725-T	rs4681725	0	4681725	intron_variant	0	0.224	4E-9	8.39794000867204	(AA)	0.046	[0.03-0.062] unit increase	Affymetrix, Illumina [17972582] (imputed)	N
rs6809499	3	56687093	G	A	0.459245	1.5926791496e-08	0.00522476604473	0.000924529754551	48	3	56686329	rs6762851	2019-05-21	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Height	approximately 458,000 European ancestry individuals		3p14.3	""	TASOR	""	""	ENSG00000163946			rs6762851-?	rs6762851	0	6762851	intron_variant	0	NR	8E-47	46.0969100130081	""		""	NR [~ 8900000] (imputed)	N
rs6814349	4	66474805	A	G	0.299205	3.64298614811e-08	0.0054072539206	0.000981826987543	57	4	66496914	rs74944857	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		4q13.2	Intergenic	EPHA5	""	""	ENSG00000145242			rs74944857-T	rs74944857	0	74944857	intron_variant	0	0.3223	9E-13	12.0457574905607	(MTAG)	0.01	[0.0073-0.0127] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs6814349	4	66474805	A	G	0.299205	3.64298614811e-08	0.0054072539206	0.000981826987543	57	4	66422737	rs62300402	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		4q13.2	NR	EPHA5	""	""	ENSG00000145242			rs62300402-?	rs62300402	0	62300402	intron_variant	0	NR	4E-6	5.39794000867204	""	4.59	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs6814349	4	66474805	A	G	0.299205	3.64298614811e-08	0.0054072539206	0.000981826987543	57	4	66520667	rs6838677	2019-04-15	30696823	Jones SE	2019-01-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/30696823	Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms.	Chronotype	449,734  European ancestry individuals	248,098 European ancestry individuals	4q13.2	EPHA5	EPHA5	""	""	ENSG00000145242			rs6838677-C	rs6838677	0	6838677	intron_variant	0	0.33109999999999995	3E-8	7.52287874528034	""	1.0215285	""	Affymetrix [11880941] (imputed)	N
rs6814349	4	66474805	A	G	0.299205	3.64298614811e-08	0.0054072539206	0.000981826987543	57	4	66446903	rs74498418	2022-11-17	36324656	Baselmans B	2021-10-06	Biol Psychiatry Glob Open Sci	www.ncbi.nlm.nih.gov/pubmed/36324656	The Genetic and Neural Substrates of Externalizing Behavior.	Risk-taking behavior (multivariate analysis)	1,506,537 European ancestry individuals		4q13.2	""	EPHA5	""	""	ENSG00000145242			rs74498418-?	rs74498418	0	74498418	intron_variant	0	NR	1E-8	8	""		""	NR [NR]	N
rs6814349	4	66474805	A	G	0.299205	3.64298614811e-08	0.0054072539206	0.000981826987543	57	4	66496914	rs74944857	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		4q13.2	Intergenic	EPHA5	""	""	ENSG00000145242			rs74944857-T	rs74944857	0	74944857	intron_variant	0	0.3299	5E-13	12.301029995664	(MTAG)	0.0176	[0.013-0.022] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs6814349	4	66474805	A	G	0.299205	3.64298614811e-08	0.0054072539206	0.000981826987543	57	4	66496914	rs74944857	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		4q13.2	""	EPHA5	""	""	ENSG00000145242			rs74944857-T	rs74944857	0	74944857	intron_variant	0	0.3223	4E-9	8.39794000867204	""	0.0089	[0.006-0.0118] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs7020815	9	126338776	T	C	0.204771	5.7611875815e-10	0.00757069758987	0.00122170501472	125	9	126351423	rs10986064	2022-03-07	34910505	van der Meer D	2021-12-15	Sci Adv	www.ncbi.nlm.nih.gov/pubmed/34910505	The genetic architecture of human cortical folding.	Vertex-wise cortical surface area	8,072 individuals		9q33.3	""	DENND1A	""	""	ENSG00000119522			rs10986064-T	rs10986064	0	10986064	intron_variant	0	0.21	4E-6	5.39794000867204	""		""	NR [13131314] (imputed)	N
rs7020815	9	126338776	T	C	0.204771	5.7611875815e-10	0.00757069758987	0.00122170501472	125	9	126335818	rs76282124	2022-11-23	35164939	van der Meer D	2022-02-11	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35164939	Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology.	Brain morphology (MOSTest)	33,735 white British ancestry individuals		9q33.3	""	DENND1A	""	""	ENSG00000119522			rs76282124-?	rs76282124	0	76282124	intron_variant	0	NR	4E-19	18.397940008672	""		""	NR [9061072] (imputed)	N
rs7020815	9	126338776	T	C	0.204771	5.7611875815e-10	0.00757069758987	0.00122170501472	125	9	126329270	rs12342546	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		9q33.3	Intergenic	DENND1A	""	""	ENSG00000119522			rs12342546-A	rs12342546	0	12342546	intron_variant	0	0.2441	4E-14	13.397940008672	(MTAG)	0.0117	[0.0088-0.0146] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs7020815	9	126338776	T	C	0.204771	5.7611875815e-10	0.00757069758987	0.00122170501472	125	9	126335211	rs28661002	2022-08-04	35505052	Fan CC	2022-05-03	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/35505052	Multivariate genome-wide association study on tissue-sensitive diffusion metrics highlights pathways that shape the human brain.	Whole brain restricted directional diffusion (multivariate analysis)	23,543 European ancestry individuals	11,555 European ancestry individuals, 3,030 non-European ancestry individuals	9q33.3	""	DENND1A	""	""	ENSG00000119522			rs28661002-?	rs28661002	0	28661002	intron_variant	0	NR	4E-13	12.397940008672	""		""	NR [NR] (imputed)	N
rs7020815	9	126338776	T	C	0.204771	5.7611875815e-10	0.00757069758987	0.00122170501472	125	9	126378489	rs111305259	2022-03-07	34910505	van der Meer D	2021-12-15	Sci Adv	www.ncbi.nlm.nih.gov/pubmed/34910505	The genetic architecture of human cortical folding.	Vertex-wise cortical thickness	33,748 European ancestry individuals		9q33.3	""	DENND1A	""	""	ENSG00000119522			rs111305259-A	rs111305259	0	111305259	intron_variant	0	0.22	4E-20	19.397940008672	""	9.18	z score increase	Affymetrix [9061022] (imputed)	N
rs7020815	9	126338776	T	C	0.204771	5.7611875815e-10	0.00757069758987	0.00122170501472	125	9	126351423	rs10986064	2022-03-07	34910505	van der Meer D	2021-12-15	Sci Adv	www.ncbi.nlm.nih.gov/pubmed/34910505	The genetic architecture of human cortical folding.	Vertex-wise sulcal depth	33,748 European ancestry individuals		9q33.3	""	DENND1A	""	""	ENSG00000119522			rs10986064-T	rs10986064	0	10986064	intron_variant	0	0.21	4E-35	34.397940008672	""	12.37	z score increase	Affymetrix [9061022] (imputed)	N
rs7020815	9	126338776	T	C	0.204771	5.7611875815e-10	0.00757069758987	0.00122170501472	125	9	126378489	rs111305259	2021-12-15	34560273	Shadrin AA	2021-09-21	Neuroimage	www.ncbi.nlm.nih.gov/pubmed/34560273	Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.	Cortical thickness	35,657 White British ancestry individuals		9q33.3	NR	DENND1A	""	""	ENSG00000119522			rs111305259-A	rs111305259	0	111305259	intron_variant	0	0.1834	1E-17	17	""		""	NR [9056863] (imputed)	N
rs7020815	9	126338776	T	C	0.204771	5.7611875815e-10	0.00757069758987	0.00122170501472	125	9	126335818	rs76282124	2020-10-23	32665545	van der Meer D	2020-07-14	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/32665545	Understanding the genetic determinants of the brain with MOSTest.	Cortical surface area (MOSTest)	26,502 European ancestry individuals		9q33.3	MITF	DENND1A	""	""	ENSG00000119522			rs76282124-?	rs76282124	0	76282124	intron_variant	0	""	9E-12	11.0457574905607	""		""	NR [7428630] (imputed)	N
rs7020815	9	126338776	T	C	0.204771	5.7611875815e-10	0.00757069758987	0.00122170501472	125	9	126351423	rs10986064	2022-03-07	34910505	van der Meer D	2021-12-15	Sci Adv	www.ncbi.nlm.nih.gov/pubmed/34910505	The genetic architecture of human cortical folding.	Vertex-wise cortical surface area	33,748 European ancestry individuals		9q33.3	""	DENND1A	""	""	ENSG00000119522			rs10986064-T	rs10986064	0	10986064	intron_variant	0	0.21	8E-26	25.0969100130081	""	10.51	z score increase	Affymetrix [9061022] (imputed)	N
rs7020815	9	126338776	T	C	0.204771	5.7611875815e-10	0.00757069758987	0.00122170501472	125	9	126335211	rs28661002	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		9q33.3	""	DENND1A	""	""	ENSG00000119522			rs28661002-T	rs28661002	0	28661002	intron_variant	0	0.757	1E-25	25	""	0.0127997	[0.01-0.015] unit increase	Illumina [10675380] (imputed)	N
rs7020815	9	126338776	T	C	0.204771	5.7611875815e-10	0.00757069758987	0.00122170501472	125	9	126329270	rs12342546	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		9q33.3	""	DENND1A	""	""	ENSG00000119522			rs12342546-A	rs12342546	0	12342546	intron_variant	0	0.2441	1E-14	14	""	0.0128	[0.0095-0.0161] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs7020815	9	126338776	T	C	0.204771	5.7611875815e-10	0.00757069758987	0.00122170501472	125	9	126425818	rs56250933	2021-12-15	34560273	Shadrin AA	2021-09-21	Neuroimage	www.ncbi.nlm.nih.gov/pubmed/34560273	Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.	Cortical surface area	35,657 White British ancestry individuals		9q33.3	NR	DENND1A	""	""	ENSG00000119522			rs56250933-G	rs56250933	0	56250933	intron_variant	0	0.1732	1E-17	17	""		""	NR [9056863] (imputed)	N
rs708973	20	3090848	G	T	0.311133	5.84615446081e-09	-0.00563553629014	0.000968122211083	197	20	3119133	rs306757	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		20p13	""	UBOX5-AS1, UBOX5	""	""	ENSG00000235958, ENSG00000185019			rs306757-A	rs306757	0	306757	intron_variant	0	0.3604	2E-8	7.69897000433602	""	0.00609278	[0.004-0.0082] unit increase	Illumina [10675380] (imputed)	N
rs708973	20	3090848	G	T	0.311133	5.84615446081e-09	-0.00563553629014	0.000968122211083	197	20	3119555	rs857252	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		20p13	NR	UBOX5-AS1, UBOX5	""	""	ENSG00000235958, ENSG00000185019			rs857252-?	rs857252	0	857252	intron_variant	0	NR	8E-6	5.09691001300806	""	4.461	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs7102360	11	38487147	C	A	0.498012	1.37881867938e-19	-0.00734683240045	0.000811450082735	139	11	38604075	rs1481294	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		11p12	""	DNAAF11P1 - LINC02759	ENSG00000254784	ENSG00000255175	""	369726	35739	rs1481294-A	rs1481294	0	1481294	intergenic_variant	1	0.4531	8E-11	10.0969100130081	""	0.00683569	[0.0048-0.0089] unit decrease	Illumina [10675380] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112877408	rs9919557	2018-10-17	30150663	Pasman JA	2018-08-27	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/30150663	GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia.	Cannabis use	184,765 European ancestry individuals		11q23.2	NCAM1	NCAM1	""	""	ENSG00000149294			rs9919557-T	rs9919557	0	9919557	intron_variant	0	0.614	1E-10	10	""	0.055	[0.037-0.073] unit decrease	Affymetrix, Illumina [11733371] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112827048	rs2186710	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Neuroticism	449,484 European ancestry individuals		11q23.2	NR	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	331758	4922	rs2186710-C	rs2186710	0	2186710	upstream_gene_variant	1	NR	1E-14	14	""	7.744	z score decrease	Affymetrix [10847151] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112846713	rs11214441	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Neuroticism	523,783 European ancestry individuals	59,206 European ancestry individuals	11q23.2	NR	NCAM1	""	""	ENSG00000149294			rs11214441-A	rs11214441	0	11214441	intron_variant	0	0.395866708999966	8E-15	14.0969100130081	""	0.011739225	[0.0088-0.0147] unit increase	NR [NR]	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112877304	rs9919670	2019-11-26	31689377	Wootton RE	2019-11-06	Psychol Med	www.ncbi.nlm.nih.gov/pubmed/31689377	Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study.	Lifetime smoking index	462,690 European ancestry individuals		11q23.2	""	NCAM1	""	""	ENSG00000149294			rs9919670-G	rs9919670	0	9919670	intron_variant	0	0.612	8E-27	26.0969100130081	""	0.022	[0.018-0.026] unit decrease	Affymetrix [up to 90000000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112826867	rs2212450	2022-10-26	36150907	Hatoum AS	2022-07-14	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/36150907	Genome-wide Association Study Shows That Executive Functioning Is Influenced by GABAergic Processes and Is a Neurocognitive Genetic Correlate of Psychiatric Disorders.	Common executive function	427,037 European ancestry individuals		11q23.2	""	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	331577	5103	rs2212450-?	rs2212450	0	2212450	downstream_gene_variant	1	NR	2E-9	8.69897000433602	""		""	Affymetrix [7391068] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112877408	rs9919557	2021-09-08	33859377	Thorp JG	2021-04-15	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/33859377	Symptom-level modelling unravels the shared genetic architecture of anxiety and depression.	Depression	at least 5,919 European ancestry cases, at least 130,691 European ancestry controls	634,037 European ancestry cases, 1,308,690 European ancestry controls	11q23.2	NCAM1	NCAM1	""	""	ENSG00000149294			rs9919557-T	rs9919557	0	9919557	intron_variant	0	0.4344	7E-7	6.15490195998574	""	0.011342609	[0.0062-0.0165] unit decrease	NR [9417325] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112877408	rs9919557	2022-05-27	35235886	Song W	2022-02-17	Psychiatry Res	www.ncbi.nlm.nih.gov/pubmed/35235886	Genome-wide identification of the shared genetic basis of cannabis and cigarette smoking and schizophrenia implicates NCAM1 and neuronal abnormality.	Cannabis smoking or cigarette smoking or schizophrenia	780,649 European ancestry individuals		11q23.2	""	NCAM1	""	""	ENSG00000149294			rs9919557-?	rs9919557	0	9919557	intron_variant	0	NR	1E-33	33	""		""	NR [NR]	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112869404	rs1940701	2022-09-14	35879402	Deak JD	2022-07-25	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35879402	Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci.	Opioid use disorder (MTAG)	15,251 European ancestry cases, 538,935 European ancestry controls, 5,435 African ancestry cases, 79,442 African ancestry controls		11q23.2	""	NCAM1	""	""	ENSG00000149294			rs1940701-?	rs1940701	0	1940701	intron_variant	0	NR	1E-9	9	""	6.1	Z score decrease	Affymetrix, Illumina [NR] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112827048	rs2186710	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		11q23.2	Intergenic	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	331758	4922	rs2186710-C	rs2186710	0	2186710	upstream_gene_variant	1	0.5927	8E-11	10.0969100130081	(MTAG)	0.0151	[0.011-0.02] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112846713	rs11214441	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Positive affect	410,603 European ancestry individuals		11q23.2	NR	NCAM1	""	""	ENSG00000149294			rs11214441-A	rs11214441	0	11214441	intron_variant	0	0.395866708999966	1E-14	14	""	0.008991173	[0.0067-0.0113] unit increase	NR [NR]	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112827048	rs2186710	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		11q23.2	NR	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	331758	4922	rs2186710-?	rs2186710	0	2186710	upstream_gene_variant	1	NR	2E-6	5.69897000433602	""	4.714	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112851068	rs2155290	2019-03-18	30643258	Karlsson Linner R	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643258	Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.	Number of sexual partners	370,711 European ancestry individuals		11q23.2	NCAM1	NCAM1	""	""	ENSG00000149294			rs2155290-C	rs2155290	0	2155290	intron_variant	0	0.6167	5E-11	10.301029995664	""	0.015957858	[0.011-0.021] unit decrease	Affymetrix [11515109] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112869054	rs10891487	2022-04-05	34855049	Pasman JA	2021-12-02	Behav Genet	www.ncbi.nlm.nih.gov/pubmed/34855049	Genetic Risk for Smoking: Disentangling Interplay Between Genes and Socioeconomic Status.	Lifetime smoking (without educational attainment)	272,943 European or unknown ancestry cases, 226,795 European or unknown ancestry controls		11q23.2	""	NCAM1	""	""	ENSG00000149294			rs10891487-?	rs10891487	0	10891487	intron_variant	0	NR	7E-35	34.1549019599857	""		""	NR [1300000]	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112834153	rs7111153	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		11q23.2	Intergenic	NCAM1	""	""	ENSG00000149294			rs7111153-T	rs7111153	0	7111153	non_coding_transcript_exon_variant	0	0.6012	1E-20	20	(MTAG)	0.017	[0.013-0.021] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112909396	rs7947502	2019-08-29	31046077	Zhong VW	2019-05-02	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/31046077	A genome-wide association study of bitter and sweet beverage consumption.	Coffee consumption	335,909 European ancestry individuals	39,924 European ancestry individuals	11q23.2	NCAM1	NCAM1	""	""	ENSG00000149294			rs7947502-C	rs7947502	0	7947502	intron_variant	0	0.4063	6E-7	6.22184874961636	""	0.0075	[0.0046-0.0104] unit increase	Affymetrix [~ 7740000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112851068	rs2155290	2019-03-18	30643258	Karlsson Linner R	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643258	Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.	Risk-taking tendency (4-domain principal component model)	315,894 European ancestry individuals		11q23.2	NCAM1	NCAM1	""	""	ENSG00000149294			rs2155290-C	rs2155290	0	2155290	intron_variant	0	0.617	4E-24	23.397940008672	""	0.026843483	[0.022-0.032] unit decrease	Affymetrix [~ 11515000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112830782	rs11214436	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Diastolic blood pressure	340,162 European ancestry individuals, 145,515 East Asian ancestry individuals		11q23.2	""	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	335492	1188	rs11214436-T	rs11214436	0	11214436	non_coding_transcript_exon_variant	1	NR	2E-8	7.69897000433602	""	0.0114	[0.0075-0.0153] unit decrease	Affymetrix, Illumina [20537302] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112830526	rs10891480	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Systolic blood pressure	340,159 European ancestry individuals, 145,505 East Asian ancestry individuals		11q23.2	""	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	335236	1444	rs10891480-G	rs10891480	0	10891480	non_coding_transcript_exon_variant	1	NR	2E-13	12.698970004336	""	0.0142	[0.01-0.018] unit decrease	Affymetrix, Illumina [20537302] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112827048	rs2186710	2020-07-07	31972866	Nagel M	2020-01-23	Acta Psychiatr Scand	www.ncbi.nlm.nih.gov/pubmed/31972866	Genome-wide association study of the sensitivity to environmental stress and adversity (SESA) neuroticism cluster.	Sensitivity to environmental stress and adversity	351,827 European ancestry individuals		11q23.2	NR	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	331758	4922	rs2186710-G	rs2186710	0	2186710	upstream_gene_variant	1	NR	2E-8	7.69897000433602	""	0.01344	NR unit increase	NR [7259579]	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112877408	rs9919557	2022-09-07	35898629	Yin B	2022-07-11	Front Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35898629	Shared Genetics and Causality Between Decaffeinated Coffee Consumption and Neuropsychiatric Diseases: A Large-Scale Genome-Wide Cross-Trait Analysis and Mendelian Randomization Analysis.	Decaffeinated coffee consumption and/or lifetime cannabis use	64,717 decaffeinated coffee drinking cases, 43,380 lifetime cannabis use cases, 383,656 controls		11q23.2	""	NCAM1	""	""	ENSG00000149294			rs9919557-?	rs9919557	0	9919557	intron_variant	0	NR	1E-10	10	""		""	NR [NR]	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112842976	rs7126748	2021-05-19	33082346	Xu K	2020-10-20	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/33082346	Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals.	Smoking status (current vs never)	40,456 European ancestry current smokers, 13,511 African American current smokers, 2,920 Hispanic current smokers, 59,056 European ancestry mostly never smokers, 17,751 African American mostly never smokers, 7,195 Hispanic mostly never smokers		11q23.2	NCAM1	NCAM1	""	""	ENSG00000149294			rs7126748-T	rs7126748	0	7126748	intron_variant	0	""	4E-8	7.39794000867204	""	0.954	[NR]	Affymetrix [~ 79000000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112910783	rs2155292	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		11q23.2	Intergenic	NCAM1	""	""	ENSG00000149294			rs2155292-A	rs2155292	0	2155292	intron_variant	0	0.5992	9E-17	16.0457574905607	(MTAG)	0.014	[0.011-0.017] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112826867	rs2212450	2021-05-05	33888516	Zheng T	2021-04-22	Gut	www.ncbi.nlm.nih.gov/pubmed/33888516	Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease.	Haemorrhoidal disease	218,920 European ancestry cases, 725,213 European ancestry controls		11q23.2	NCAM1	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	331577	5103	rs2212450-?	rs2212450	0	2212450	downstream_gene_variant	1	0.43420000000000003	5E-11	10.301029995664	""	1.03	[1.02-1.04]	Affymetrix, Illumina [8494288] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112866456	rs4144892	2019-04-18	30617275	Erzurumluoglu AM	2019-01-07	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/30617275	Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.	Smoking initiation	324,851 European ancestry individuals, 21,962 South Asian ancestry individuals	up to 275,596 European ancestry individuals	11q23.2	NCAM1	NCAM1	""	""	ENSG00000149294			rs4144892 -T	rs4144892	0	4144892	intron_variant	0	NR	7E-25	24.1549019599857	""	0.023	[0.018-0.028] unit increase (replication)	Affymetrix, Illumina [up to 1207583] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112826867	rs2212450	2020-10-07	32606422	Wu Y	2020-06-30	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/32606422	Multi-trait analysis for genome-wide association study of five psychiatric disorders.	Depressive symptoms (MTAG)	955,012 individuals		11q23.2	NR	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	331577	5103	rs2212450-?	rs2212450	0	2212450	downstream_gene_variant	1	""	5E-9	8.30102999566398	""		""	NR [520857]	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112827715	rs4937872	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Worry	348,219 European ancestry individuals		11q23.2	NR	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	332425	4255	rs4937872-G	rs4937872	0	4937872	upstream_gene_variant	1	NR	1E-9	9	""	0.01489	[0.01-0.02] unit increase	Affymetrix [10847151] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112911004	rs7938812	2019-03-18	30643258	Karlsson Linner R	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643258	Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.	Smoking status (ever vs never smokers)	518,633 European ancestry individuals		11q23.2	NCAM1	NCAM1	""	""	ENSG00000149294			rs7938812-T	rs7938812	0	7938812	intron_variant	0	0.6095	7E-48	47.1549019599858	""	0.029930087	[0.026-0.034] unit decrease	Affymetrix [11514654] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112834153	rs7111153	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability	564,698 European ancestry individuals		11q23.2	Intergenic	NCAM1	""	""	ENSG00000149294			rs7111153-T	rs7111153	0	7111153	non_coding_transcript_exon_variant	0	0.6012	4E-18	17.397940008672	""	0.0173	[0.013-0.021] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112827048	rs2186710	2022-09-07	35898629	Yin B	2022-07-11	Front Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35898629	Shared Genetics and Causality Between Decaffeinated Coffee Consumption and Neuropsychiatric Diseases: A Large-Scale Genome-Wide Cross-Trait Analysis and Mendelian Randomization Analysis.	Decaffeinated coffee consumption and/or neuroticism	64,717 decaffeinated coffee drinking cases, 380,060 individuals with neuroticism measurements, 264,954 controls		11q23.2	""	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	331758	4922	rs2186710-?	rs2186710	0	2186710	upstream_gene_variant	1	NR	2E-13	12.698970004336	""		""	NR [NR]	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112869054	rs10891487	2022-04-05	34855049	Pasman JA	2021-12-02	Behav Genet	www.ncbi.nlm.nih.gov/pubmed/34855049	Genetic Risk for Smoking: Disentangling Interplay Between Genes and Socioeconomic Status.	Lifetime smoking	272,943 European or unknown ancestry cases, 226,795 European or unknown ancestry controls		11q23.2	""	NCAM1	""	""	ENSG00000149294			rs10891487-?	rs10891487	0	10891487	intron_variant	0	NR	1E-46	46	""		""	NR [1300000]	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112846713	rs11214441	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Life satisfaction	80,852 European ancestry individuals		11q23.2	NR	NCAM1	""	""	ENSG00000149294			rs11214441-A	rs11214441	0	11214441	intron_variant	0	0.395866708999966	9E-14	13.0457574905607	""	0.009536479	[0.007-0.012] unit increase	NR [NR]	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112909396	rs7947502	2021-04-16	33608531	Wu Y	2021-02-19	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/33608531	GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression.	Irritable bowel syndrome	28,518 European ancestry cases, 426,803 European ancestry controls		11q23.2	NCAM1	NCAM1	""	""	ENSG00000149294			rs7947502-C	rs7947502	0	7947502	intron_variant	0	0.41	3E-8	7.52287874528034	""	1.05	""	NR [8546065] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112830526	rs10891480	2022-05-27	35181757	Wendt FR	2022-02-18	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35181757	Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorder.	Post-traumatic stress disorder (phenotype risk score)	497,803 European ancestry individuals		11q23.2	""	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	335236	1444	rs10891480-T	rs10891480	0	10891480	non_coding_transcript_exon_variant	1	NR	2E-10	9.69897000433602	""	0.013172812	[0.0091-0.0172] unit decrease	Affymetrix [NR] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112838338	rs2155281	2019-05-02	30867560	Hill WD	2019-03-13	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/30867560	Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.	General factor of neuroticism	270,059 British ancestry individuals		11q23.2	NCAM1	NCAM1	""	""	ENSG00000149294			rs2155281-G	rs2155281	0	2155281	intron_variant	0	NR	2E-8	7.69897000433602	""	0.0098168	[0.0064-0.0132] unit increase	Affymetrix [18485882] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112839532	rs7948789	2019-10-04	30679032	Brazel DM	2018-12-06	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/30679032	Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use.	Smoking initiation (ever regular vs never regular)	up to 433,216 European ancestry individuals		11q23.2	NCAM1	NCAM1	""	""	ENSG00000149294			rs7948789-G	rs7948789	0	7948789	intron_variant	0	0.386	6E-27	26.2218487496164	""	0.0252	[0.021-0.03] unit increase	Illumina [~ 250000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112830526	rs10891480	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Mean arterial pressure	360,863 European ancestry individuals, 145,502 East Asian ancestry individuals		11q23.2	""	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	335236	1444	rs10891480-G	rs10891480	0	10891480	non_coding_transcript_exon_variant	1	NR	1E-10	10	""	0.0126	[0.0087-0.0165] unit decrease	Affymetrix, Illumina [20537389] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112851068	rs2155290	2020-05-29	32231276	Cai N	2020-03-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32231276	Minimal phenotyping yields genome-wide association signals of low specificity for major depression.	Smoking status (ever vs never smokers)	336,066 British ancestry individuals		11q23.2	NR	NCAM1	""	""	ENSG00000149294			rs2155290-G	rs2155290	0	2155290	intron_variant	0	0.3826	9E-36	35.0457574905607	""	1.067	[1.06-1.08]	NR [8968716] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112846713	rs11214441	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Depressive symptoms	1,067,913 European ancestry individuals	228,033 European ancestry individuals	11q23.2	NR	NCAM1	""	""	ENSG00000149294			rs11214441-A	rs11214441	0	11214441	intron_variant	0	0.395866708999966	1E-14	14	""	0.0074607884	[0.0056-0.0094] unit increase	NR [NR]	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112846713	rs11214441	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Well-being spectrum (multivariate analysis)	2,083,151 European ancestry individuals	287,239 European ancestry individuals	11q23.2	NR	NCAM1	""	""	ENSG00000149294			rs11214441-A	rs11214441	0	11214441	intron_variant	0	0.395866708999966	4E-15	14.397940008672	""	0.0073846052	[0.0055-0.0092] unit increase	NR [NR]	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112912811	rs2155646	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Smoking initiation (ever regular vs never regular) (MTAG)	up to 1,359,002 European ancestry individuals		11q23.2	NR	NCAM1	""	""	ENSG00000149294			rs2155646-C	rs2155646	0	2155646	intron_variant	0	0.4	3E-61	60.5228787452803	""	0.0181277	[0.016-0.02] unit increase	NR [9732723] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112843616	rs2186709	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Age of smoking initiation (MTAG)	up to 931,815 European ancestry  individuals		11q23.2	NR	NCAM1	""	""	ENSG00000149294			rs2186709-G	rs2186709	0	2186709	intron_variant	0	0.6	2E-24	23.698970004336	""	0.0152334	[0.012-0.018] unit increase	NR [9732723] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112826867	rs2212450	2019-11-05	30239722	Pulit SL	2018-09-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/30239722	Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry.	Body mass index	434,794 European ancestry female individuals		11q23.2		LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	331577	5103	rs2212450-T	rs2212450	0	2212450	downstream_gene_variant	1	0.5703	2E-6	5.69897000433602	""	0.0081	[0.0048-0.0114] unit increase	NR [~ 27400000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112912048	rs7105462	2022-08-04	35585065	May-Wilson S	2022-05-18	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/35585065	Large-scale GWAS of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits.	F-cooking vegetables liking (derived food-liking factor)	158,645 European ancestry individuals		11q23.2	""	NCAM1	""	""	ENSG00000149294			rs7105462-A	rs7105462	0	7105462	intron_variant	0	0.5969	1E-9	9	""	0.06889	[0.047-0.091] unit decrease	Affymetrix [9605623] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112826867	rs2212450	2021-07-27	33479212	Yao X	2021-01-21	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/33479212	Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders.	Major depressive disorder (MTAG)	at least 170,756 European ancestry cases, at least 329,443 European ancestry controls		11q23.2	NR	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	331577	5103	rs2212450-T	rs2212450	0	2212450	downstream_gene_variant	1	0.5723	9E-9	8.04575749056068	""	0.02432692	[0.016-0.033] unit decrease	NR [NR]	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112861434	rs4466874	2019-09-13	26423011	Wain LV	2015-09-27	Lancet Respir Med	www.ncbi.nlm.nih.gov/pubmed/26423011	Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank.	Smoking status (heavy vs never)	24,457 European ancestry heavy smokers, 24,474 European ancestry never smokers		11q23.2	NCAM1	NCAM1	""	""	ENSG00000149294			rs4466874-C	rs4466874	0	4466874	intron_variant	0	0.385	3E-12	11.5228787452803	""	1.1	[1.07-1.13]	Affymetrix [28509962] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112912048	rs7105462	2021-02-18	33287642	Said MA	2020-12-08	J Am Heart Assoc	www.ncbi.nlm.nih.gov/pubmed/33287642	Associations of Observational and Genetically Determined Caffeine Intake With Coronary Artery Disease and Diabetes Mellitus.	Caffeine consumption from coffee or tea	362,316 European ancestry individuals		11q23.2	NCAM1, ARL6IP1	NCAM1	""	""	ENSG00000149294			rs7105462-G	rs7105462	0	7105462	intron_variant	0	0.40559	2E-9	8.69897000433602	""	0.014163	[0.0095-0.0188] unit increase	Affymetrix [19400838] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112912811	rs2155646	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Smoking status	approximately 458,000 European ancestry individuals		11q23.2	""	NCAM1	""	""	ENSG00000149294			rs2155646-?	rs2155646	0	2155646	intron_variant	0	NR	2E-43	42.698970004336	""		""	NR [~ 8900000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112912303	rs3802847	2022-08-05	35835914	Watanabe K	2022-07-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35835914	Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.	Insomnia	593,724 European ancestry cases, 1,771,286 European ancestry controls		11q23.2	""	NCAM1	""	""	ENSG00000149294			rs3802847-T	rs3802847	0	3802847	intron_variant	0	NR	6E-9	8.22184874961636	""	0.005	[0.003-0.007] unit decrease	Illumina [10713943] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112912518	rs3802850	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken	430,445 European ancestry individuals		11q23.2	Intergenic	NCAM1	""	""	ENSG00000149294			rs3802850-A	rs3802850	0	3802850	intron_variant	0	0.5988	3E-11	10.5228787452803	""	0.0154	[0.011-0.02] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112912811	rs2155646	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Smoking initiation (ever regular vs never regular)	up to 1,232,091 European ancestry individuals		11q23.2	NR	NCAM1	""	""	ENSG00000149294			rs2155646-C	rs2155646	0	2155646	intron_variant	0	0.4	9E-48	47.0457574905607	""	0.037777152	[0.033-0.043] unit increase	NR [~ 10000000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112827715	rs4937872	2022-09-07	35898629	Yin B	2022-07-11	Front Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35898629	Shared Genetics and Causality Between Decaffeinated Coffee Consumption and Neuropsychiatric Diseases: A Large-Scale Genome-Wide Cross-Trait Analysis and Mendelian Randomization Analysis.	Decaffeinated coffee consumption or major depression disorder	64,717 decaffeinated coffee drinking cases, 170,756 major depressive disorder cases, 594,397 controls		11q23.2	""	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	332425	4255	rs4937872-?	rs4937872	0	4937872	upstream_gene_variant	1	NR	8E-9	8.09691001300806	""		""	NR [NR]	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112877409	rs9919558	2021-11-02	34446935	Karlsson Linner R	2021-08-26	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/34446935	Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.	Externalizing behaviour (multivariate analysis)	up to 53,293 European ancestry Attention-deficit/hyperactivity disorder individuals, up to 164,684 European ancestry problematic alcohol use individuals, up to 186,875 European ancestry lifetime cannabis use individuals, up to 357,187 European ancestry individuals measuring  reverse-coded age at first sexual intercourse, up to 336,121 European ancestry individuals measuring number of sexual partners, up to 426,379 European ancestry individuals measuring general risk tolerance, up to 1,251,809  European ancestry individuals measuring lifetime smoking initiation		11q23.2	""	NCAM1	""	""	ENSG00000149294			rs9919558-T	rs9919558	0	9919558	intron_variant	0	0.613	7E-59	58.1549019599857	""	0.02	[0.018-0.022] unit decrease	NR [NR] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112885527	rs10891490	2021-09-08	34431594	Atkins JL	2021-08-25	Aging Cell	www.ncbi.nlm.nih.gov/pubmed/34431594	A genome-wide association study of the frailty index highlights brain pathways in ageing.	Frailty index	175,226 European ancestry individuals		11q23.2	NCAM1	NCAM1	""	""	ENSG00000149294			rs10891490-T	rs10891490	0	10891490	intron_variant	0	0.4085	2E-8	7.69897000433602	""	0.0188	[0.012-0.025] unit increase	Affymetrix, Illumina [7666890] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112905129	rs7128648	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Neuroticism	approximately 372,000 European ancestry individuals		11q23.2	""	NCAM1	""	""	ENSG00000149294			rs7128648-?	rs7128648	0	7128648	intron_variant	0	NR	7E-15	14.1549019599857	""		""	NR [~ 8900000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112830663	rs10789929	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Neurociticism	380,506 European ancestry individuals		11q23.2	NCAM1	NA - NCAM1	""	ENSG00000149294	""		1307	rs10789929-T	rs10789929	0	10789929	non_coding_transcript_exon_variant	1	0.393947	4E-12	11.397940008672	""	6.95	z score increase	NR [10847151] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112877409	rs9919558	2022-11-17	36324656	Baselmans B	2021-10-06	Biol Psychiatry Glob Open Sci	www.ncbi.nlm.nih.gov/pubmed/36324656	The Genetic and Neural Substrates of Externalizing Behavior.	Risk-taking behavior (multivariate analysis)	1,506,537 European ancestry individuals		11q23.2	""	NCAM1	""	""	ENSG00000149294			rs9919558-?	rs9919558	0	9919558	intron_variant	0	NR	3E-29	28.5228787452803	""		""	NR [NR]	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112851068	rs2155290	2022-08-04	35585065	May-Wilson S	2022-05-18	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/35585065	Large-scale GWAS of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits.	Avocado liking	153,095 European ancestry individuals		11q23.2	""	NCAM1	""	""	ENSG00000149294			rs2155290-G	rs2155290	0	2155290	intron_variant	0	0.3811	5E-8	7.30102999566398	""	0.020347	[0.013-0.028] unit increase	Affymetrix [11353280] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112851961	rs2298527	2021-02-18	33287642	Said MA	2020-12-08	J Am Heart Assoc	www.ncbi.nlm.nih.gov/pubmed/33287642	Associations of Observational and Genetically Determined Caffeine Intake With Coronary Artery Disease and Diabetes Mellitus.	Caffeine consumption from coffee	373,522 European ancestry individuals		11q23.2	NCAM1	NCAM1	""	""	ENSG00000149294			rs2298527-G	rs2298527	0	2298527	intron_variant	0	0.405568	2E-10	9.69897000433602	""	0.014947	[0.01-0.02] unit increase	Affymetrix [19400838] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112827715	rs4937872	2021-09-08	33859377	Thorp JG	2021-04-15	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/33859377	Symptom-level modelling unravels the shared genetic architecture of anxiety and depression.	Anxiety	at least 23,606 European ancestry cases, at least 113,351 European ancestry controls	624,615 European ancestry cases, 1,310,854 European ancestry controls	11q23.2	RP11, 629G13.1	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	332425	4255	rs4937872-A	rs4937872	0	4937872	upstream_gene_variant	1	0.4543	2E-14	13.698970004336	""	0.018045627	[0.013-0.023] unit decrease	NR [9417325] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112860579	rs7106434	2021-11-22	34741163	Eijsbouts C	2021-11-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34741163	Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders.	Irritable bowel syndrome	53,400 European ancestry cases, 433,201 European ancestry controls	205,252 European ancestry cases, 1,384,055 European ancestry controls	11q23.2	NR	NCAM1	""	""	ENSG00000149294			rs7106434-T	rs7106434	0	7106434	intron_variant	0	0.4095	9E-11	10.0457574905607	""	0.020919405	[0.014-0.027] unit increase	Illumina [9885498] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112843138	rs7110863	2021-05-19	33082346	Xu K	2020-10-20	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/33082346	Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals.	Smoking initiation	842,717 European ancestry individuals		11q23.2	NCAM1	NCAM1	""	""	ENSG00000149294			rs7110863-G	rs7110863	0	7110863	intron_variant	0	""	2E-35	34.698970004336	""	1.045	[NR]	Affymetrix [up to 79000000] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112843138	rs7110863	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Smoking cessation (MTAG)	up to 820,192 European ancestry individuals		11q23.2	NR	NCAM1	""	""	ENSG00000149294			rs7110863-G	rs7110863	0	7110863	intron_variant	0	0.404	3E-11	10.5228787452803	""	0.0103841	[0.0073-0.0134] unit increase	NR [9732723] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112827715	rs4937872	2022-05-27	35181757	Wendt FR	2022-02-18	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35181757	Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorder.	Post-traumatic stress disorder (mental health questionnaire or predicted)	497,803 European ancestry individuals		11q23.2	""	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	332425	4255	rs4937872-A	rs4937872	0	4937872	upstream_gene_variant	1	NR	4E-9	8.39794000867204	""	0.012073822	[0.008-0.0161] unit decrease	Affymetrix [NR] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112852195	rs1940728	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Alcohol consumption (drinks per week) (MTAG)	up to 1,039,210 European ancestry individuals		11q23.2	NR	NCAM1	""	""	ENSG00000149294			rs1940728-T	rs1940728	0	1940728	intron_variant	0	0.403	3E-14	13.5228787452803	""	0.0103804	[0.0077-0.0131] unit increase	NR [~ 9732723] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112851961	rs2298527	2018-02-01	29255261	Luciano M	2017-12-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29255261	Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.	Neuroticism	329,821 European ancestry individuals	122,867 European ancestry individuals	11q23.2	intergenic	NCAM1	""	""	ENSG00000149294			rs2298527-C	rs2298527	0	2298527	intron_variant	0	0.58222	3E-11	10.5228787452803	""	6.653	unit decrease	Illumina [18485882] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112827715	rs4937872	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Feeling tense	371,318 European ancestry individuals		11q23.2	NCAM1	LINC02763 - NCAM1	ENSG00000254968	ENSG00000149294	""	332425	4255	rs4937872-A	rs4937872	0	4937872	upstream_gene_variant	1	0.417009	5E-11	10.301029995664	""	6.57	z score decrease	NR [10847151] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112851961	rs2298527	2022-08-04	35585065	May-Wilson S	2022-05-18	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/35585065	Large-scale GWAS of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits.	Cabbage liking	159,516 European ancestry individuals		11q23.2	""	NCAM1	""	""	ENSG00000149294			rs2298527-C	rs2298527	0	2298527	intron_variant	0	0.5967	4E-8	7.39794000867204	""	0.01989	[0.013-0.027] unit decrease	Affymetrix [11353280] (imputed)	N
rs7106434	11	112860579	C	T	0.44831	4.92134468019e-08	-0.00513622609327	0.000941713337668	148	11	112852195	rs1940728	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Depressed affect	357,957 European ancestry individuals		11q23.2	NR	NCAM1	""	""	ENSG00000149294			rs1940728-?	rs1940728	0	1940728	intron_variant	0	NR	1E-8	8	""	0.01354	[0.0089-0.0182] unit increase	Affymetrix [10847151] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57650796	rs2509805	2019-03-19	30718901	Howard DM	2019-02-04	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/30718901	Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.	Depression	118,811 European ancestry cases, 327,427 European ancestry controls, 127,552 cases, 233,763 controls	414,055 European ancestry cases, 892,299 European ancestry controls	11q12.1	NR	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	9736	33973	rs2509805-T	rs2509805	0	2509805	intergenic_variant	1	0.3209	5E-16	15.301029995664	""	1.019	[1.015-1.024]	NR [8098588] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57421457	rs7117878	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Mean corpuscular hemoglobin	408,112 British individuals		11q12.1	CLP1	CLP1	""	""	ENSG00000172409			rs7117878-A	rs7117878	0	7117878	intron_variant	0	0.321894	1E-17	17	""	0.02038221	[0.016-0.025] unit decrease	Affymetrix [93095623] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57650796	rs2509805	2022-11-18	34924174	Mitchell BL	2021-11-02	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/34924174	The Australian Genetics of Depression Study: New Risk Loci and Dissecting Heterogeneity Between Subtypes.	Depression	13,318 European ancestry cases, 12,684 European ancestry controls, 246,363 cases, 561,190 controls		11q12.1	""	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	9736	33973	rs2509805-?	rs2509805	0	2509805	intergenic_variant	1	NR	7E-9	8.15490195998574	""	0.003	unit increase	Illumina [7617771] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57467035	rs11604333	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Well-being spectrum (multivariate analysis)	2,083,151 European ancestry individuals	287,239 European ancestry individuals	11q12.1	NR	ZDHHC5	""	""	ENSG00000156599			rs11604333-G	rs11604333	0	11604333	intron_variant	0	0.321224362296017	4E-13	12.397940008672	""	0.0071451203	[0.0052-0.0091] unit increase	NR [NR]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57650796	rs2509805	2021-09-30	34045744	Levey DF	2021-05-27	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/34045744	Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions.	Major depressive disorder	340,591 European ancestry cases, 813,676 European ancestry controls	455,350 cases, 887,428 controls	11q12.1	""	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	9736	33973	rs2509805-?	rs2509805	0	2509805	intergenic_variant	1	NR	5E-12	11.301029995664	""	0.0217	unit increase	NR [NR]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57448032	rs10896636	2018-02-01	29255261	Luciano M	2017-12-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29255261	Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.	Neuroticism	329,821 European ancestry individuals	122,867 European ancestry individuals	11q12.1	BTBD18, C11orf31, CLP1, CTNND1, MED19, SERPING1, TMX2, YPEL4, ZDHHC5	ZDHHC5	""	""	ENSG00000156599			rs10896636-C	rs10896636	0	10896636	intron_variant	0	0.66353	7E-11	10.1549019599857	""	6.523	unit decrease	Illumina [18485882] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57421457	rs7117878	2020-09-14	32451486	Zhou H	2020-05-25	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/32451486	Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits.	Alcohol use disorder	57,564 European ancestry cases, 256,395 European ancestry controls		11q12.1	NR	CLP1	""	""	ENSG00000172409			rs7117878-A	rs7117878	0	7117878	intron_variant	0	0.3163	8E-9	8.09691001300806	""	5.763	[NR] unit increase	Affymetrix [7003540] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57641883	rs7117205	2022-04-05	34855049	Pasman JA	2021-12-02	Behav Genet	www.ncbi.nlm.nih.gov/pubmed/34855049	Genetic Risk for Smoking: Disentangling Interplay Between Genes and Socioeconomic Status.	Educational attainment	451,800 European or unknown ancestry individuals		11q12.1	""	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	823	42886	rs7117205-?	rs7117205	0	7117205	intergenic_variant	1	NR	2E-10	9.69897000433602	""		""	NR [1300000]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57676251	rs9645687	2021-07-27	33479212	Yao X	2021-01-21	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/33479212	Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders.	Neuropsychiatric disorders	19,099 European ancestry attention deficit hyperactivity disorder cases, 18,381 European ancestry autism spectrum disorder cases, 20,352 European ancestry bipolar disorder cases, 170,756 European ancestry major depressive disorder cases, 33,640 European ancestry schizophrenia cases, 466,420 European ancestry controls		11q12.1	NR	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	35191	8518	rs9645687-T	rs9645687	0	9645687	intergenic_variant	1	NR	7E-9	8.15490195998574	""	5.795	NR z score decrease	NR [NR]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57667222	rs12790660	2022-08-05	35835914	Watanabe K	2022-07-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35835914	Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.	Insomnia	593,724 European ancestry cases, 1,771,286 European ancestry controls		11q12.1	""	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	26162	17547	rs12790660-T	rs12790660	0	12790660	regulatory_region_variant	1	NR	1E-16	16	""	0.008	[0.006-0.01] unit decrease	Illumina [10713943] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57433327	rs527528	2021-07-27	34054130	Bralten J	2021-05-30	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/34054130	Genetic underpinnings of sociability in the general population.	Sociability score	342,461 European ancestry individuals		11q12.1	ZDHHC5	CLP1 - ZDHHC5	ENSG00000172409	ENSG00000156599	""	3990	1892	rs527528-T	rs527528	0	527528	intergenic_variant	1	NR	4E-10	9.39794000867204	""	0.01405	unit decrease	Affymetrix [9327396] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57467035	rs11604333	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Neuroticism	523,783 European ancestry individuals	59,206 European ancestry individuals	11q12.1	NR	ZDHHC5	""	""	ENSG00000156599			rs11604333-G	rs11604333	0	11604333	intron_variant	0	0.321224362296017	5E-13	12.301029995664	""	0.011700453	[0.0085-0.0149] unit increase	NR [NR]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57433327	rs527528	2020-10-07	32606422	Wu Y	2020-06-30	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/32606422	Multi-trait analysis for genome-wide association study of five psychiatric disorders.	Depressive symptoms (MTAG)	955,012 individuals		11q12.1	NR	CLP1 - ZDHHC5	ENSG00000172409	ENSG00000156599	""	3990	1892	rs527528-?	rs527528	0	527528	intergenic_variant	1	""	3E-12	11.5228787452803	""		""	NR [520857]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57510294	rs9420	2019-02-21	30285260	Ikeda M	2018-10-03	Schizophr Bull	www.ncbi.nlm.nih.gov/pubmed/30285260	Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.	Schizophrenia	14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls		11q12.1	TMX2-CTNND1	SELENOH	""	""	ENSG00000211450			rs9420-A	rs9420	0	9420	non_coding_transcript_exon_variant	0	NR	4E-7	6.39794000867204	(EA)	1.0599	[1.04-1.08]	Illumina [6627481] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57681828	rs641325	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Worry too long after an embarrassing experience	367,725 European ancestry individuals		11q12.1	TIMM10	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	40768	2941	rs641325-T	rs641325	0	641325	intergenic_variant	1	0.337108	7E-10	9.15490195998574	""	6.16	z score increase	NR [10847151] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57650796	rs2509805	2021-10-21	34159505	Wang H	2021-06-16	Sci China Life Sci	www.ncbi.nlm.nih.gov/pubmed/34159505	Novel loci and potential mechanisms of major depressive disorder, bipolar disorder, and schizophrenia.	Major depressive disorder (MTAG)	119,754 European ancestry individuals		11q12.1	""	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	9736	33973	rs2509805-?	rs2509805	0	2509805	intergenic_variant	1	NR	5E-9	8.30102999566398	""		""	NR [2625067]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57435211	rs11606396	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Mean corpuscular volume	544,127 European ancestry individuals		11q12.1	NR	CLP1 - ZDHHC5	ENSG00000172409	ENSG00000156599	""	5874	8	rs11606396-T	rs11606396	0	11606396	regulatory_region_variant	1	0.326249	1E-24	24	""	0.020482	[0.017-0.024] SD unit decrease	Affymetrix, Illumina [50615308] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57667222	rs12790660	2022-08-05	35835914	Watanabe K	2022-07-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35835914	Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.	Insomnia	390,751 European ancestry female cases, 1,018,386 European ancestry female controls		11q12.1	""	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	26162	17547	rs12790660-T	rs12790660	0	12790660	regulatory_region_variant	1	NR	4E-12	11.397940008672	""	0.009	[0.007-0.011] unit decrease	Illumina [10288913] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57644334	rs6591434	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Red blood cell count	approximately 445,000 European ancestry individuals		11q12.1	""	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	3274	40435	rs6591434-?	rs6591434	0	6591434	intergenic_variant	1	NR	7E-9	8.15490195998574	""		""	NR [~ 8900000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57657413	rs685149	2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals		11q12.1	CTNND1, OR6Q1	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	16353	27356	rs685149-A	rs685149	0	685149	intergenic_variant	1	""	1E-6	6	(EA)	0.31	unit decrease	Affymetrix [at least 2696785] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57448032	rs10896636	2020-05-29	32231276	Cai N	2020-03-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32231276	Minimal phenotyping yields genome-wide association signals of low specificity for major depression.	Neuroticism	274,107 British ancestry individuals		11q12.1	NR	ZDHHC5	""	""	ENSG00000156599			rs10896636-G	rs10896636	0	10896636	intron_variant	0	0.3449	3E-11	10.5228787452803	""	0.01281	[0.009-0.0166] unit increase	NR [8968716] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57448032	rs10896636	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Neurociticism	380,506 European ancestry individuals		11q12.1	TMX2-CTNND1	ZDHHC5	""	""	ENSG00000156599			rs10896636-C	rs10896636	0	10896636	intron_variant	0	0.336471	9E-11	10.0457574905607	""	6.49	z score decrease	NR [10847151] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57665336	rs674094	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Feeling hurt	372,047 European ancestry individuals		11q12.1	TMX2-CTNND1	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	24276	19433	rs674094-A	rs674094	0	674094	intergenic_variant	1	0.293658	3E-8	7.52287874528034	""	5.53	z score increase	NR [10847151] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57667222	rs12790660	2019-06-25	30804565	Jansen PR	2019-02-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30804565	Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.	Insomnia	651,923 European ancestry males, 679,087 European ancestry females		11q12.1	NR	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	26162	17547	rs12790660-C	rs12790660	0	12790660	regulatory_region_variant	1	0.3156	4E-10	9.39794000867204	""	1.0405828	[1.03-1.05]	Affymetrix, Illumina [NR] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57433327	rs527528	2021-07-27	34054130	Bralten J	2021-05-30	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/34054130	Genetic underpinnings of sociability in the general population.	Worry too long after an embarrassing experience	342,461 European ancestry individuals		11q12.1	ZDHHC5	CLP1 - ZDHHC5	ENSG00000172409	ENSG00000156599	""	3990	1892	rs527528-?	rs527528	0	527528	intergenic_variant	1	NR	4E-11	10.397940008672	""		""	Affymetrix [up to 9327396] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57448032	rs10896636	2020-10-07	32606422	Wu Y	2020-06-30	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/32606422	Multi-trait analysis for genome-wide association study of five psychiatric disorders.	Depressive symptoms	688,809 individuals		11q12.1	NR	ZDHHC5	""	""	ENSG00000156599			rs10896636-?	rs10896636	0	10896636	intron_variant	0	""	3E-9	8.52287874528034	""		""	NR [11140414]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57654991	rs78587207	2021-11-12	34104963	Thompson A	2021-06-08	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/34104963	Assessing the impact of alcohol consumption on the genetic contribution to mean corpuscular volume.	Mean corpuscular volume	362,595 British ancestry individuals		11q12.1	""	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	13931	29778	rs78587207-T	rs78587207	0	78587207	intergenic_variant	1	0.681	8E-10	9.09691001300806	""	0.07	[0.05-0.1] % increase	Affymetrix [NR] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57448032	rs10896636	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Depression	688,809 European ancestry individuals		11q12.1	NR	ZDHHC5	""	""	ENSG00000156599			rs10896636-C	rs10896636	0	10896636	intron_variant	0	NR	3E-9	8.52287874528034	""	5.958	z score decrease	Affymetrix [10847151] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57448032	rs10896636	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Neuroticism	449,484 European ancestry individuals		11q12.1	NR	ZDHHC5	""	""	ENSG00000156599			rs10896636-C	rs10896636	0	10896636	intron_variant	0	NR	7E-13	12.1549019599857	""	7.175	z score decrease	Affymetrix [10847151] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57570680	rs3781885	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		11q12.1	NR	CTNND1	""	""	ENSG00000198561			rs3781885-?	rs3781885	0	3781885	intron_variant	0	NR	2E-6	5.69897000433602	""	4.709	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57510294	rs9420	2017-11-10	28991256	Li Z	2017-10-09	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28991256	Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.	Schizophrenia	7,699 Chinese ancestry cases, 35,476 European ancestry cases, 18,327 Chinese ancestry controls, 46,839 European ancestry controls	4,384 Chinese ancestry cases, 5,770 Chinese ancestry controls	11q12.1	C11orf31, MED19, YPEL4, ZDHHC5	SELENOH	""	""	ENSG00000211450			rs9420-A	rs9420	0	9420	non_coding_transcript_exon_variant	0	NR	9E-9	8.04575749056068	""	1.061	[1.04-1.08]	Affymetrix, Illumina [up to 5107227] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57510294	rs9420	2019-02-21	30285260	Ikeda M	2018-10-03	Schizophr Bull	www.ncbi.nlm.nih.gov/pubmed/30285260	Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.	Schizophrenia	14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls		11q12.1	TMX2-CTNND1	SELENOH	""	""	ENSG00000211450			rs9420-A	rs9420	0	9420	non_coding_transcript_exon_variant	0	NR	2E-8	7.69897000433602	""	1.061	[1.04-1.08]	Illumina [6627481] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57641883	rs7117205	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Neurociticism	380,506 European ancestry individuals		11q12.1	NR	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	823	42886	rs7117205-T	rs7117205	0	7117205	intergenic_variant	1	0.312314	6E-10	9.22184874961636	""	6.2	z score decrease	NR [10847151] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57467035	rs11604333	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Depressive symptoms	1,067,913 European ancestry individuals	228,033 European ancestry individuals	11q12.1	NR	ZDHHC5	""	""	ENSG00000156599			rs11604333-G	rs11604333	0	11604333	intron_variant	0	0.321224362296017	6E-13	12.2218487496164	""	0.0074086282	[0.0054-0.0094] unit increase	NR [NR]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57657413	rs685149	2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals		11q12.1	CTNND1, OR6Q1	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	16353	27356	rs685149-A	rs685149	0	685149	intergenic_variant	1	""	5E-7	6.30102999566398	""	0.299	unit decrease	Affymetrix [at least 2696785] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57435211	rs11606396	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Mean corpuscular hemoglobin	486,823 European ancestry individuals		11q12.1	NR	CLP1 - ZDHHC5	ENSG00000172409	ENSG00000156599	""	5874	8	rs11606396-T	rs11606396	0	11606396	regulatory_region_variant	1	0.327317	8E-23	22.0969100130081	""	0.020904	[0.017-0.025] SD unit decrease	Affymetrix, Illumina [50266654] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57497847	rs12790196	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		11q12.1	Intergenic	TMX2	""	""	ENSG00000213593			rs12790196-T	rs12790196	0	12790196	intron_variant	0	0.3241	1E-33	33	(MTAG)	0.0214	[0.018-0.025] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57560452	rs11570190	2020-02-11	31835028	Cross-Disorder Group of the Psychiatric Genomics Consortium	2019-12-01	Cell	www.ncbi.nlm.nih.gov/pubmed/31835028	Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy)	19,009 European ancestry ADHD cases, 3,495 European ancestry anorexia cases, 18,381 European ancestry autism cases, 20,352 European ancestry bipolar disorder cases, 130,664 European ancestry major depression cases, 2,688 European ancestry OCD cases, 33,640 European ancestry schizophrenia cases, 4,645 European ancestry Tourette's cases, 494,162 European ancestry controls		11q12.1	CTNND1, BTBD18	CTNND1	""	""	ENSG00000198561			rs11570190-?	rs11570190	0	11570190	intron_variant	0	""	1E-10	10	""		""	NR [6786993] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57650796	rs2509805	2022-05-27	35181757	Wendt FR	2022-02-18	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35181757	Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorder.	Post-traumatic stress disorder (mental health questionnaire or predicted)	497,803 European ancestry individuals		11q12.1	""	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	9736	33973	rs2509805-T	rs2509805	0	2509805	intergenic_variant	1	NR	5E-12	11.301029995664	""	0.014981963	[0.011-0.019] unit increase	Affymetrix [NR] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57510294	rs9420	2019-08-19	31268507	Periyasamy S	2019-07-03	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/31268507	Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study.	Schizophrenia	816 Indian ancestry cases, 900 Indian ancestry controls, 505 Indian ancestry cases and 871 Indian ancestry controls from 405 families, up to 36,989 European and unknown ancestry cases, up to 113,075 European and unknown ancestry controls		11q12.1	NR	SELENOH	""	""	ENSG00000211450			rs9420-?	rs9420	0	9420	non_coding_transcript_exon_variant	0	NR	7E-8	7.15490195998574	""		""	Illumina [up to 5582932] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57510294	rs9420	2016-07-23	26198764	Goes FS	2015-07-21	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/26198764	Genome-wide association study of schizophrenia in Ashkenazi Jews.	Schizophrenia	592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls		11q12.1	NR	SELENOH	""	""	ENSG00000211450			rs9420-A	rs9420	0	9420	non_coding_transcript_exon_variant	0	NR	2E-8	7.69897000433602	""	1.06	[NR]	Illumina [7158791] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57497847	rs12790196	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		11q12.1	Intergenic	TMX2	""	""	ENSG00000213593			rs12790196-T	rs12790196	0	12790196	intron_variant	0	0.3263	5E-18	17.301029995664	(MTAG)	0.0122	[0.0095-0.0149] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57676251	rs9645687	2021-07-27	33479212	Yao X	2021-01-21	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/33479212	Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders.	Major depressive disorder (MTAG)	at least 170,756 European ancestry cases, at least 329,443 European ancestry controls		11q12.1	NR	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	35191	8518	rs9645687-T	rs9645687	0	9645687	intergenic_variant	1	0.685999999999999	9E-10	9.04575749056067	""	0.027032098	[0.018-0.036] unit decrease	NR [NR]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57484660	rs7129727	2017-08-16	28540026	Anney RJL	2017-05-22	Mol Autism	www.ncbi.nlm.nih.gov/pubmed/28540026	Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.	Autism spectrum disorder or schizophrenia	schizophrenia cases and controls (see Ripke, 2014), up to 6,197 European ancestry ASD cases, up to 7,377 European ancestry controls, up to 1,190 ASD cases, up to 1,190 controls		11q12.1	BTBD18, C11orf31, CLP1, CTNND1, MED19, MIR130A, SERPING1, TMX2, TMX2-CTNND1, YPEL4, ZDHHC5	TMX2	""	""	ENSG00000213593			rs7129727-A	rs7129727	0	7129727	intron_variant	0	""	5E-8	7.30102999566398	""	1.06	[1.04-1.08]	Affymetrix, Illumina [NR]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57484660	rs7129727	2018-12-17	29483656	Pardinas AF	2018-02-26	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29483656	Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.	Schizophrenia	40,675 European ancestry cases, 64,643 European ancestry controls	1,651 European ancestry cases, 4,111 cases, 142,717 European ancestry controls, 11,507 controls	11q12.1	BTBD18, C11orf31, CLP1, CTNND1, MED19, MIR130A, SERPING1, TMX2, TMX2-CTNND1, YPEL4, ZDHHC5	TMX2	""	""	ENSG00000213593			rs7129727-?	rs7129727	0	7129727	intron_variant	0	NR	1E-9	9	""	1.0649627	[1.04-1.09]	Illumina [8000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57424040	rs10896633	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Positive affect	410,603 European ancestry individuals		11q12.1	NR	CLP1	""	""	ENSG00000172409			rs10896633-C	rs10896633	0	10896633	intron_variant	0	0.313202569570006	1E-9	9	""	0.00856035	[0.0058-0.0113] unit increase	NR [NR]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57424040	rs10896633	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Mean corpuscular volume	350,473 European ancestry individuals, 129,832 East Asian ancestry individuals		11q12.1	""	CLP1	""	""	ENSG00000172409			rs10896633-C	rs10896633	0	10896633	intron_variant	0	NR	2E-14	13.698970004336	""	0.018	[0.013-0.023] unit decrease	Affymetrix, Illumina [20535844] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57421457	rs7117878	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Mean corpuscular volume	408,112 British individuals		11q12.1	CLP1	CLP1	""	""	ENSG00000172409			rs7117878-A	rs7117878	0	7117878	intron_variant	0	0.321871	3E-14	13.5228787452803	""	0.0201941	[0.016-0.025] unit decrease	Affymetrix [93095623] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57421457	rs7117878	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Mean corpuscular hemoglobin	approximately 443,000 European ancestry individuals		11q12.1	""	CLP1	""	""	ENSG00000172409			rs7117878-?	rs7117878	0	7117878	intron_variant	0	NR	5E-28	27.301029995664	""		""	NR [~ 8900000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57497847	rs12790196	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		11q12.1	""	TMX2	""	""	ENSG00000213593			rs12790196-T	rs12790196	0	12790196	intron_variant	0	0.3263	3E-11	10.5228787452803	""	0.0101	[0.0072-0.013] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57480623	rs576859	2020-09-14	32451486	Zhou H	2020-05-25	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/32451486	Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits.	Problematic alcohol use	435,563 European ancestry individuals		11q12.1	TMX2	TMX2	""	""	ENSG00000213593			rs576859-A	rs576859	0	576859	intron_variant	0	0.3272	1E-8	8	""	5.67	[NR] z score increase	Affymetrix [14069427] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57639017	rs7936998	2022-08-30	32193382	Cole JB	2020-03-19	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/32193382	Comprehensive genomic analysis of dietary habits in UK Biobank identifies hundreds of genetic associations.	Principal component-derived dietary pattern 3	449,210 European ancestry individuals		11q12.1	""	OR5BA1P	""	""	ENSG00000255303			rs7936998-G	rs7936998	0	7936998	intron_variant	0	0.671954	3E-11	10.5228787452803	""	0.0270246	[0.019-0.035] unit increase	NR [NR] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57570680	rs3781885	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Pulse pressure	360,863 European ancestry individuals, 145,445 East Asian ancestry individuals		11q12.1	""	CTNND1	""	""	ENSG00000198561			rs3781885-T	rs3781885	0	3781885	intron_variant	0	NR	2E-12	11.698970004336	""	0.0152	[0.011-0.02] unit decrease	Affymetrix, Illumina [20537391] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57421457	rs7117878	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Mean corpuscular hemoglobin	350,472 European ancestry individuals, 128,028 East Asian ancestry individuals		11q12.1	""	CLP1	""	""	ENSG00000172409			rs7117878-A	rs7117878	0	7117878	intron_variant	0	NR	5E-16	15.301029995664	""	0.0191	[0.015-0.024] unit decrease	Affymetrix, Illumina [20535878] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57496820	rs11607056	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Life satisfaction	80,852 European ancestry individuals		11q12.1	NR	TMX2	""	""	ENSG00000213593			rs11607056-T	rs11607056	0	11607056	intron_variant	0	0.321125266629361	1E-10	10	""	0.009177176	[0.0064-0.012] unit increase	NR [NR]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57433327	rs527528	2020-07-07	31972866	Nagel M	2020-01-23	Acta Psychiatr Scand	www.ncbi.nlm.nih.gov/pubmed/31972866	Genome-wide association study of the sensitivity to environmental stress and adversity (SESA) neuroticism cluster.	Sensitivity to environmental stress and adversity	351,827 European ancestry individuals		11q12.1	NR	CLP1 - ZDHHC5	ENSG00000172409	ENSG00000156599	""	3990	1892	rs527528-T	rs527528	0	527528	intergenic_variant	1	NR	7E-14	13.1549019599857	""	0.01856	NR unit increase	NR [7259579]	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57657413	rs685149	2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Systolic blood pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals		11q12.1	CTNND1, OR6Q1	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	16353	27356	rs685149-A	rs685149	0	685149	intergenic_variant	1	""	2E-13	12.698970004336	""	0.311	unit decrease	Affymetrix [at least 2696785] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57448032	rs10896636	2019-05-02	30867560	Hill WD	2019-03-13	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/30867560	Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.	General factor of neuroticism	270,059 British ancestry individuals		11q12.1	ZDHHC5	ZDHHC5	""	""	ENSG00000156599			rs10896636-C	rs10896636	0	10896636	intron_variant	0	NR	3E-9	8.52287874528034	""	0.010268	[0.0069-0.0137] unit increase	Affymetrix [18485882] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57510294	rs9420	2019-12-23	31740837	Lam M	2019-11-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/31740837	Comparative genetic architectures of schizophrenia in East Asian and European populations.	Schizophrenia	22,778 East Asian ancestry cases, 35,362 East Asian ancestry controls, 33,640 European ancestry cases, 43,456 European ancestry controls		11q12.1	NR	SELENOH	""	""	ENSG00000211450			rs9420-?	rs9420	0	9420	non_coding_transcript_exon_variant	0	NR	7E-9	8.15490195998574	""	1.05834	[1.04-1.08]	Affymetrix, Illumina [12447948] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57570680	rs3781885	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Worry too long after an embarrassing experience	367,725 European ancestry individuals		11q12.1	NR	CTNND1	""	""	ENSG00000198561			rs3781885-T	rs3781885	0	3781885	intron_variant	0	0.305304	1E-11	11	""	6.77	z score increase	NR [10847151] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57657413	rs685149	2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals		11q12.1	CTNND1, OR6Q1	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	16353	27356	rs685149-A	rs685149	0	685149	intergenic_variant	1	""	1E-11	11	""	0.186	unit decrease	Affymetrix [at least 2696785] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57510294	rs9420	2015-04-16	25056061	Ripke S	2014-07-22	Nature	www.ncbi.nlm.nih.gov/pubmed/25056061	Biological insights from 108 schizophrenia-associated genetic loci.	Schizophrenia	32,405 European ancestry cases, 42,221 European ancestry controls, 1,235 European ancestry cases and 1,235 European ancestry controls from 1235 parent-offspring trios, 1,836 East Asian ancestry cases, 3,383 East Asian ancestry controls	1,513 European ancestry cases, 66,236 European ancestry controls	11q12.1	BTBD18, C11orf31, CLP1, CTNND1, MED19, SERPING1, TMX2, YPEL4, ZDHHC5	SELENOH	""	""	ENSG00000211450			rs9420-A	rs9420	0	9420	non_coding_transcript_exon_variant	0	0.311	2E-9	8.69897000433602	""	1.068	[1.045-1.092]	Affymetrix, Illumina [9005918] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57448032	rs10896636	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Neuroticism	approximately 372,000 European ancestry individuals		11q12.1	""	ZDHHC5	""	""	ENSG00000156599			rs10896636-?	rs10896636	0	10896636	intron_variant	0	NR	9E-13	12.0457574905607	""		""	NR [~ 8900000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57618068	rs7932091	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken	430,445 European ancestry individuals		11q12.1	Intergenic	CTNND1 - OR5BA1P	ENSG00000198561	ENSG00000255303	""	31050	11352	rs7932091-A	rs7932091	0	7932091	intergenic_variant	1	0.6796	9E-23	22.0457574905607	""	0.0238	[0.019-0.029] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57450720	rs488769	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Mean corpuscular volume	696,882 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals		11q12.1	NR	ZDHHC5	""	""	ENSG00000156599			rs488769-C	rs488769	0	488769	intron_variant	0	0.295653	5E-23	22.301029995664	""		""	Affymetrix, Illumina [24246363] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57448032	rs10896636	2021-09-08	33859377	Thorp JG	2021-04-15	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/33859377	Symptom-level modelling unravels the shared genetic architecture of anxiety and depression.	Anxiety	at least 23,606 European ancestry cases, at least 113,351 European ancestry controls	624,615 European ancestry cases, 1,310,854 European ancestry controls	11q12.1	ZDHHC5	ZDHHC5	""	""	ENSG00000156599			rs10896636-C	rs10896636	0	10896636	intron_variant	0	0.3221	7E-14	13.1549019599857	""	0.01800239	[0.013-0.023] unit decrease	NR [9417325] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57600285	rs12807250	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		11q12.1	Intergenic	CTNND1 - OR5BA1P	ENSG00000198561	ENSG00000255303	""	13267	29135	rs12807250-T	rs12807250	0	12807250	intergenic_variant	1	0.3238	7E-33	32.1549019599857	(MTAG)	0.0228	[0.019-0.027] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57657413	rs685149	2019-02-10	27841878	Hoffmann TJ	2016-11-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27841878	Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.	Pulse pressure	80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals		11q12.1	CTNND1, OR6Q1	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	16353	27356	rs685149-A	rs685149	0	685149	intergenic_variant	1	""	4E-6	5.39794000867204	""	0.181	unit decrease	Affymetrix [at least 2696785] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57448032	rs10896636	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		11q12.1	""	ZDHHC5	""	""	ENSG00000156599			rs10896636-C	rs10896636	0	10896636	intron_variant	0	0.6588	2E-17	16.698970004336	""	0.0093576	[0.0072-0.0115] unit increase	Illumina [10675380] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57600285	rs12807250	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability	564,698 European ancestry individuals		11q12.1	Intergenic	CTNND1 - OR5BA1P	ENSG00000198561	ENSG00000255303	""	13267	29135	rs12807250-C	rs12807250	0	12807250	intergenic_variant	1	0.6762	2E-28	27.698970004336	""	0.0231	[0.019-0.027] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57585662	rs708228	2022-09-27	35396580	Trubetskoy V	2022-04-08	Nature	www.ncbi.nlm.nih.gov/pubmed/35396580	Mapping genomic loci implicates genes and synaptic biology in schizophrenia.	Schizophrenia	53,386 European ancestry cases, 77,258 European ancestry controls, 14,004 East Asian ancestry cases, 16,757 East Asian ancestry controls, 6,152 African American cases, 3,918 African American controls, 1,234 Latino cases, 3,090 Latino controls	1,979 European ancestry cases, 142,626 European ancestry controls	11q12.1	""	CTNND1	""	""	ENSG00000198561			rs708228-C	rs708228	0	708228	3_prime_UTR_variant	0	0.734	3E-10	9.52287874528034	""	0.95009	[0.93-0.97]	Affymetrix [7585078] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57657141	rs673344	2018-02-01	29255261	Luciano M	2017-12-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29255261	Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.	Neuroticism	329,821 European ancestry individuals	122,867 European ancestry individuals	11q12.1	intergenic	OR5BA1P - OR5AZ1P	ENSG00000255303	ENSG00000180714	""	16081	27628	rs673344-A	rs673344	0	673344	intergenic_variant	1	0.6898	1E-10	10	""	6.423	unit decrease	Illumina [18485882] (imputed)	N
rs11607122	11	57389737	A	G	0.270378	6.13961472368e-10	0.00650017754766	0.00105065189429	140	11	57450720	rs488769	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Mean corpuscular hemoglobin	630,125 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals		11q12.1	NR	ZDHHC5	""	""	ENSG00000156599			rs488769-C	rs488769	0	488769	intron_variant	0	0.292869	3E-21	20.5228787452803	""		""	Affymetrix, Illumina [20825802] (imputed)	N
rs724877	16	13921340	G	A	0.185885	2.503788031e-08	-0.0062832247031	0.00112743876901	175	16	13918873	rs8048012	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		16p13.12	""	TMF1P1 - ERCC4	ENSG00000262235	ENSG00000175595	""	366318	95122	rs8048012-A	rs8048012	0	8048012	regulatory_region_variant	1	0.1729	3E-9	8.52287874528034	""	0.00821599	[0.0055-0.0109] unit increase	Illumina [10675380] (imputed)	N
rs7612999	3	35678337	A	G	0.238569	3.111004706e-08	0.00595295125384	0.00107549661829	45	3	35671945	rs9818103	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Waist-hip ratio	approximately 458,000 European ancestry individuals		3p22.3	""	RNU6-243P - ARPP21	ENSG00000212442	ENSG00000172995	""	373507	8492	rs9818103-?	rs9818103	0	9818103	intergenic_variant	1	NR	5E-8	7.30102999566398	""		""	NR [~ 8900000] (imputed)	N
rs7612999	3	35678337	A	G	0.238569	3.111004706e-08	0.00595295125384	0.00107549661829	45	3	35674248	rs9867068	2020-04-17	31669095	Zhu Z	2019-10-24	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/31669095	Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank.	Waist-to-hip ratio adjusted for BMI	457,690 European ancestry individuals		3p22.3	NR	NA - ARPP21	""	ENSG00000172995	""		6189	rs9867068-?	rs9867068	0	9867068	intergenic_variant	1	NR	6E-9	8.22184874961636	""		""	Affymetrix [~ 8270000] (imputed)	N
rs7612999	3	35678337	A	G	0.238569	3.111004706e-08	0.00595295125384	0.00107549661829	45	3	35635145	rs10490869	2019-11-04	30239722	Pulit SL	2018-09-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/30239722	Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry.	Waist-hip ratio	697,734 European ancestry individuals		3p22.3		NA - ARPP21	""	ENSG00000172995	""		45292	rs10490869-A	rs10490869	0	10490869	intergenic_variant	1	0.7964	9E-17	16.0457574905607	""	0.0183	[0.014-0.023] unit decrease	NR [~ 27400000] (imputed)	N
rs7612999	3	35678337	A	G	0.238569	3.111004706e-08	0.00595295125384	0.00107549661829	45	3	35671945	rs9818103	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		3p22.3	""	RNU6-243P - ARPP21	ENSG00000212442	ENSG00000172995	""	373507	8492	rs9818103-A	rs9818103	0	9818103	intergenic_variant	1	0.7522	4E-7	6.39794000867204	""	0.00611867	[0.0037-0.0085] unit increase	Illumina [10675380] (imputed)	N
rs7612999	3	35678337	A	G	0.238569	3.111004706e-08	0.00595295125384	0.00107549661829	45	3	35678337	rs7612999	2019-09-22	30575882	Lotta LA	2018-12-01	JAMA	www.ncbi.nlm.nih.gov/pubmed/30575882	Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.	Waist-hip ratio	663,598 European ancestry individuals		3p22.3	NR	NA - ARPP21	""	ENSG00000172995	""		2100	rs7612999-A	rs7612999	0	7612999	intergenic_variant	1	0.25	5E-8	7.30102999566398	""		""	Affymetrix [2446094] (imputed)	N
rs7612999	3	35678337	A	G	0.238569	3.111004706e-08	0.00595295125384	0.00107549661829	45	3	35678337	rs7612999	2019-11-04	30239722	Pulit SL	2018-09-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/30239722	Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry.	Waist-hip ratio	381,152 European female individuals		3p22.3	NR	NA - ARPP21	""	ENSG00000172995	""		2100	rs7612999-A	rs7612999	0	7612999	intergenic_variant	1	0.2469	5E-16	15.301029995664	""	0.0168	[0.013-0.021] unit increase	NR [~ 27400000] (imputed)	N
rs7612999	3	35678337	A	G	0.238569	3.111004706e-08	0.00595295125384	0.00107549661829	45	3	35674248	rs9867068	2021-08-24	34021172	Christakoudi S	2021-05-21	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/34021172	GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer.	Waist-hip index	219,872 British ancestry women		3p22.3	ARPP21	NA - ARPP21	""	ENSG00000172995	""		6189	rs9867068-G	rs9867068	0	9867068	intergenic_variant	1	NR	8E-11	10.0969100130081	""	0.0211929	[0.015-0.028] unit increase	Affymetrix [319769] (imputed)	N
rs7612999	3	35678337	A	G	0.238569	3.111004706e-08	0.00595295125384	0.00107549661829	45	3	35636709	rs11129657	2019-11-04	30239722	Pulit SL	2018-09-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/30239722	Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry.	Waist-to-hip ratio adjusted for BMI	379,501 European ancestry female individuals		3p22.3	NR	NA - ARPP21	""	ENSG00000172995	""		43728	rs11129657-T	rs11129657	0	11129657	intergenic_variant	1	0.7925	2E-11	10.698970004336	""	0.0147	[0.01-0.019] unit decrease	NR [~ 27400000] (imputed)	N
rs7612999	3	35678337	A	G	0.238569	3.111004706e-08	0.00595295125384	0.00107549661829	45	3	35678337	rs7612999	2019-09-22	30575882	Lotta LA	2018-12-01	JAMA	www.ncbi.nlm.nih.gov/pubmed/30575882	Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.	Waist-to-hip ratio adjusted for BMI	660,648 European ancestry individuals		3p22.3	NR	NA - ARPP21	""	ENSG00000172995	""		2100	rs7612999-A	rs7612999	0	7612999	intergenic_variant	1	0.25	4E-11	10.397940008672	""	0.014	[0.0099-0.0181] unit increase	Affymetrix [2446094] (imputed)	N
rs7612999	3	35678337	A	G	0.238569	3.111004706e-08	0.00595295125384	0.00107549661829	45	3	35674248	rs9867068	2021-08-24	34021172	Christakoudi S	2021-05-21	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/34021172	GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer.	Waist-to-hip ratio adjusted for BMI	219,872 British ancestry women		3p22.3	ARPP21	NA - ARPP21	""	ENSG00000172995	""		6189	rs9867068-G	rs9867068	0	9867068	intergenic_variant	1	NR	5E-11	10.301029995664	""	0.0214734	[0.015-0.028] unit increase	Affymetrix [319769] (imputed)	N
rs7683755	4	10301757	G	A	0.249503	6.46771942638e-15	0.00925590931037	0.0011874962952	54	4	10296114	rs6839820	2021-09-08	33832965	Sandoval-Plata G	2021-04-08	Ann Rheum Dis	www.ncbi.nlm.nih.gov/pubmed/33832965	Variants in urate transporters, ADH1B, GCKR and MEPE genes associate with transition from asymptomatic hyperuricaemia to gout: results of the first gout versus asymptomatic hyperuricaemia GWAS in Caucasians using data from the UK Biobank.	Gout	7,049 European ancestry cases, 64,424 European ancestry controls		4p16.1	Intergenic	RAF1P1 - NA	ENSG00000250040	""	""	37869		rs6839820-C	rs6839820	0	6839820	non_coding_transcript_exon_variant	1	0.33	8E-27	26.0969100130081	""	1.24	[1.19-1.29]	Affymetrix [710030]	N
rs7683755	4	10301757	G	A	0.249503	6.46771942638e-15	0.00925590931037	0.0011874962952	54	4	10117430	rs73212886	2022-03-07	34910505	van der Meer D	2021-12-15	Sci Adv	www.ncbi.nlm.nih.gov/pubmed/34910505	The genetic architecture of human cortical folding.	Vertex-wise cortical surface area	33,748 European ancestry individuals		4p16.1	""	WDR1, RNA5SP155	""	""	ENSG00000071127, ENSG00000223086			rs73212886-T	rs73212886	0	73212886	non_coding_transcript_exon_variant	0	0.23	6E-10	9.22184874961636	""	6.18	z score increase	Affymetrix [9061022] (imputed)	N
rs7683755	4	10301757	G	A	0.249503	6.46771942638e-15	0.00925590931037	0.0011874962952	54	4	10116852	rs12501855	2021-12-15	34560273	Shadrin AA	2021-09-21	Neuroimage	www.ncbi.nlm.nih.gov/pubmed/34560273	Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.	Cortical surface area	35,657 White British ancestry individuals		4p16.1	NR	WDR1	""	""	ENSG00000071127			rs12501855-C	rs12501855	0	12501855	intron_variant	0	0.2174	3E-13	12.5228787452803	""		""	NR [9056863] (imputed)	N
rs7683755	4	10301757	G	A	0.249503	6.46771942638e-15	0.00925590931037	0.0011874962952	54	4	10136121	rs73808713	2022-11-23	35164939	van der Meer D	2022-02-11	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35164939	Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology.	Brain morphology (MOSTest)	33,735 white British ancestry individuals		4p16.1	""	WDR1 - RAF1P1	ENSG00000071127	ENSG00000250040	""	17548	120429	rs73808713-?	rs73808713	0	73808713	intergenic_variant	1	NR	2E-11	10.698970004336	""		""	NR [9061072] (imputed)	N
rs802459	7	86308038	G	A	0.356859	5.78101143109e-09	-0.005562403109	0.000955251502473	101	7	86322686	rs802456	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		7q21.11	Intergenic	GRM3	""	""	ENSG00000198822			rs802456-T	rs802456	0	802456	intron_variant	0	0.3557	9E-17	16.0457574905607	(MTAG)	0.0155	[0.012-0.019] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs802459	7	86308038	G	A	0.356859	5.78101143109e-09	-0.005562403109	0.000955251502473	101	7	86230375	rs10241183	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		7q21.11	""	SOCS5P1 - GRM3	ENSG00000236610	ENSG00000198822	""	383326	42850	rs10241183-T	rs10241183	0	10241183	regulatory_region_variant	1	0.3563	2E-20	19.698970004336	""	0.0101267	[0.008-0.0123] unit decrease	Illumina [10675380] (imputed)	N
rs802459	7	86308038	G	A	0.356859	5.78101143109e-09	-0.005562403109	0.000955251502473	101	7	86237581	rs1405876	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		7q21.11	Intergenic	NA - GRM3	""	ENSG00000198822	""		35644	rs1405876-T	rs1405876	0	1405876	intergenic_variant	1	0.6491	4E-20	19.397940008672	(MTAG)	0.0159	[0.013-0.019] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs802459	7	86308038	G	A	0.356859	5.78101143109e-09	-0.005562403109	0.000955251502473	101	7	86237581	rs1405876	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		7q21.11	Intergenic	NA - GRM3	""	ENSG00000198822	""		35644	rs1405876-T	rs1405876	0	1405876	intergenic_variant	1	0.6403	5E-17	16.301029995664	(MTAG)	0.0114	[0.0087-0.0141] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs802459	7	86308038	G	A	0.356859	5.78101143109e-09	-0.005562403109	0.000955251502473	101	7	86239031	rs58882293	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken	430,445 European ancestry individuals		7q21.11	Intergenic	NA - GRM3	""	ENSG00000198822	""		34194	rs58882293-A	rs58882293	0	58882293	intergenic_variant	1	0.6493	2E-9	8.69897000433602	""	0.0142	[0.0095-0.0189] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs802459	7	86308038	G	A	0.356859	5.78101143109e-09	-0.005562403109	0.000955251502473	101	7	86258737	rs2526952	2019-02-06	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Body mass index	approximately 458,000 European ancestry individuals		7q21.11	""	NA - GRM3	""	ENSG00000198822	""		14488	rs2526952-?	rs2526952	0	2526952	regulatory_region_variant	1	NR	3E-8	7.52287874528034	""		""	NR [~ 8900000] (imputed)	N
rs802459	7	86308038	G	A	0.356859	5.78101143109e-09	-0.005562403109	0.000955251502473	101	7	86258736	rs2660971	2020-04-17	31669095	Zhu Z	2019-10-24	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/31669095	Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank.	Body mass index	457,822 European ancestry individuals		7q21.11	NR	NA - GRM3	""	ENSG00000198822	""		14489	rs2660971-?	rs2660971	0	2660971	regulatory_region_variant	1	NR	1E-8	8	""		""	Affymetrix [~ 8270000] (imputed)	N
rs802459	7	86308038	G	A	0.356859	5.78101143109e-09	-0.005562403109	0.000955251502473	101	7	86237581	rs1405876	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		7q21.11	""	NA - GRM3	""	ENSG00000198822	""		35644	rs1405876-T	rs1405876	0	1405876	intergenic_variant	1	0.6403	8E-14	13.0969100130081	""	0.0109	[0.008-0.0138] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs802459	7	86308038	G	A	0.356859	5.78101143109e-09	-0.005562403109	0.000955251502473	101	7	86322686	rs802456	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability	564,698 European ancestry individuals		7q21.11	Intergenic	GRM3	""	""	ENSG00000198822			rs802456-T	rs802456	0	802456	intron_variant	0	0.3557	2E-13	12.698970004336	""	0.0149	[0.011-0.019] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs802459	7	86308038	G	A	0.356859	5.78101143109e-09	-0.005562403109	0.000955251502473	101	7	86249396	rs146312	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		7q21.11	Intergenic	NA - GRM3	""	ENSG00000198822	""		23829	rs146312-T	rs146312	0	146312	intergenic_variant	1	0.3475	5E-12	11.301029995664	(MTAG)	0.0166	[0.012-0.021] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	83370070	rs28737193	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		15q25.2	Intergenic	AP3B2	""	""	ENSG00000103723			rs28737193-T	rs28737193	0	28737193	intron_variant	0	0.2084	4E-11	10.397940008672	(MTAG)	0.0106	[0.0075-0.0137] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	83403726	rs8028130	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		15q25.2	NR	ACTG1P17	""	""	ENSG00000259315			rs8028130-T	rs8028130	0	8028130	intron_variant	0	NR	3E-9	8.52287874528034	""	5.948	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	83398315	rs7163848	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		15q25.2	NR	ACTG1P17	""	""	ENSG00000259315			rs7163848-?	rs7163848	0	7163848	intron_variant	0	NR	5E-8	7.30102999566398	""	5.451	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	83403726	rs8028130	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		15q25.2	""	ACTG1P17	""	""	ENSG00000259315			rs8028130-?	rs8028130	0	8028130	intron_variant	0	NR	7E-9	8.15490195998574	""		""	NR [6307410] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	83370070	rs28737193	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		15q25.2	Intergenic	AP3B2	""	""	ENSG00000103723			rs28737193-T	rs28737193	0	28737193	intron_variant	0	0.207	4E-11	10.397940008672	(MTAG)	0.0187	[0.013-0.024] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	83370070	rs28737193	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		15q25.2	Intergenic	AP3B2	""	""	ENSG00000103723			rs28737193-T	rs28737193	0	28737193	intron_variant	0	0.2131	2E-9	8.69897000433602	(MTAG)	0.0121	[0.0082-0.016] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	83384069	rs28607761	2021-06-29	33462484	Sinnott-Armstrong N	2021-01-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33462484	Genetics of 35 blood and urine biomarkers in the UK Biobank.	Estimated glomerular filtration rate	342,376 European ancestry individuals, 6,016 African ancestry individuals, 7,339 South Asian ancestry individuals		15q25.2	NR	AP3B2 - ACTG1P17	ENSG00000103723	ENSG00000259315	""	5205	10556	rs28607761-G	rs28607761	0	28607761	intergenic_variant	1	NR	2E-14	13.698970004336	""	0.0229	[0.017-0.029] unit decrease	Affymetrix [9000000] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	83384069	rs28607761	2021-06-29	33462484	Sinnott-Armstrong N	2021-01-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/33462484	Genetics of 35 blood and urine biomarkers in the UK Biobank.	Creatinine levels	342,376 European ancestry individuals, 6,016 African ancestry individuals, 7,339 South Asian ancestry individuals		15q25.2	NR	AP3B2 - ACTG1P17	ENSG00000103723	ENSG00000259315	""	5205	10556	rs28607761-G	rs28607761	0	28607761	intergenic_variant	1	NR	3E-14	13.5228787452803	""	0.0227	[0.017-0.029] unit increase	Affymetrix [9000000] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82513121	rs28420834	2022-03-15	34743297	Kulminski AM	2021-11-06	Geroscience	www.ncbi.nlm.nih.gov/pubmed/34743297	Pleiotropic predisposition to Alzheimer's disease and educational attainment: insights from the summary statistics analysis.	Alzheimer's disease or educational attainment (pleiotropy)	(see Lambert 2013 and Okbay 2016)		15q25.2	""	EFL1	""	""	ENSG00000140598			rs28420834-A	rs28420834	0	28420834	intron_variant	0	0.4291	3E-9	8.52287874528034	""	45.66343	z score increase	NR [6814003]	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82438346	rs867371	2018-01-12	29186694	Lam M	2017-11-28	Cell Rep	www.ncbi.nlm.nih.gov/pubmed/29186694	Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.	Cognitive ability (MTAG)	436,124 European ancestry individuals		15q25.2	EFTUD1	EFL1	""	""	ENSG00000140598			rs867371-?	rs867371	0	867371	intron_variant	0	NR	1E-10	10	""	6.43	z score increase	Affymetrix, Illumina, Perlegen [7333576] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82438346	rs867371	2018-01-12	29186694	Lam M	2017-11-28	Cell Rep	www.ncbi.nlm.nih.gov/pubmed/29186694	Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.	Cognitive ability	107,207 European ancestry individuals		15q25.2	EFTUD1	EFL1	""	""	ENSG00000140598			rs867371-?	rs867371	0	867371	intron_variant	0	NR	3E-6	5.52287874528034	""	4.705	z score increase	Affymetrix, Illumina [7357080] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82558034	rs3858954	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		15q25.2	FAM154B	SAXO2	""	""	ENSG00000188659			rs3858954-C	rs3858954	0	3858954	missense_variant	0	NR	3E-8	7.52287874528034	""	5.557	z-score increase	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82513121	rs28420834	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		15q25.2	EFTUD1	EFL1	""	""	ENSG00000140598			rs28420834-A	rs28420834	0	28420834	intron_variant	0	NR	1E-10	10	""	0.028913617	[0.02-0.038] unit decrease	Affymetrix [NR]	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82513121	rs28420834	2017-02-24	27225129	Okbay A	2016-05-26	Nature	www.ncbi.nlm.nih.gov/pubmed/27225129	Genome-wide association study identifies 74 loci associated with educational attainment.	Educational attainment (years of education)	405,072 European ancestry individuals		15q25.2	NR	EFL1	""	""	ENSG00000140598			rs28420834-A	rs28420834	0	28420834	intron_variant	0	0.4536	3E-10	9.52287874528034	""	0.014275947	NR unit decrease	Affymetrix, Illumina, Perlegen [~ 9300000] (imputed)	N
rs4778665	15	82436504	A	G	0.23161	2.25685040717e-13	-0.00827294240122	0.00112823723487	171	15	82437968	rs1174546	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		15q25.2	""	EFL1	""	""	ENSG00000140598			rs1174546-?	rs1174546	0	1174546	intron_variant	0	NR	5E-10	9.30102999566398	""		""	NR [6307410] (imputed)	N
rs8091177	18	37406823	A	C	0.172962	1.75925288553e-08	0.00648942230125	0.00115180176654	187	18	37416318	rs7233920	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		18q12.3	Intergenic	MIR924HG - LINC01901	ENSG00000267374	ENSG00000267413	""	36032	4820	rs7233920-A	rs7233920	0	7233920	intergenic_variant	1	0.225	1E-16	16	(MTAG)	0.0164	[0.012-0.02] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs8091177	18	37406823	A	C	0.172962	1.75925288553e-08	0.00648942230125	0.00115180176654	187	18	37416318	rs7233920	2022-04-05	34855049	Pasman JA	2021-12-02	Behav Genet	www.ncbi.nlm.nih.gov/pubmed/34855049	Genetic Risk for Smoking: Disentangling Interplay Between Genes and Socioeconomic Status.	Educational attainment	451,800 European or unknown ancestry individuals		18q12.3	""	MIR924HG - LINC01901	ENSG00000267374	ENSG00000267413	""	36032	4820	rs7233920-?	rs7233920	0	7233920	intergenic_variant	1	NR	1E-11	11	""		""	NR [1300000]	N
rs8091177	18	37406823	A	C	0.172962	1.75925288553e-08	0.00648942230125	0.00115180176654	187	18	37412228	rs12957463	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		18q12.3	""	MIR924HG - LINC01901	ENSG00000267374	ENSG00000267413	""	31942	8910	rs12957463-A	rs12957463	0	12957463	intergenic_variant	1	0.7956	6E-22	21.2218487496164	""	0.0125225	[0.01-0.0151] unit increase	Illumina [10675380] (imputed)	N
rs8091177	18	37406823	A	C	0.172962	1.75925288553e-08	0.00648942230125	0.00115180176654	187	18	37416318	rs7233920	2019-02-06	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Educational attainment (years of education)	approximately 455,000 European ancestry individuals		18q12.3	""	MIR924HG - LINC01901	ENSG00000267374	ENSG00000267413	""	36032	4820	rs7233920-?	rs7233920	0	7233920	intergenic_variant	1	NR	7E-12	11.1549019599857	""		""	NR [~ 8900000] (imputed)	N
rs8091177	18	37406823	A	C	0.172962	1.75925288553e-08	0.00648942230125	0.00115180176654	187	18	37416318	rs7233920	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		18q12.3	Intergenic	MIR924HG - LINC01901	ENSG00000267374	ENSG00000267413	""	36032	4820	rs7233920-A	rs7233920	0	7233920	intergenic_variant	1	0.2293	2E-18	17.698970004336	(MTAG)	0.0136	[0.01-0.017] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs8091177	18	37406823	A	C	0.172962	1.75925288553e-08	0.00648942230125	0.00115180176654	187	18	37416318	rs7233920	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		18q12.3	""	MIR924HG - LINC01901	ENSG00000267374	ENSG00000267413	""	36032	4820	rs7233920-A	rs7233920	0	7233920	intergenic_variant	1	0.2293	1E-14	14	(conditional-joint)	0.0129	[0.0096-0.0162] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs8091177	18	37406823	A	C	0.172962	1.75925288553e-08	0.00648942230125	0.00115180176654	187	18	37412228	rs12957463	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		18q12.3	""	MIR924HG - LINC01901	ENSG00000267374	ENSG00000267413	""	31942	8910	rs12957463-A	rs12957463	0	12957463	intergenic_variant	1	0.7953	9E-17	16.0457574905607	""	0.0146	[0.011-0.018] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126223944	rs4897160	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Hematocrit	408,112 British individuals		6q22.32	NCOA7	NCOA7	""	""	ENSG00000111912			rs4897160-A	rs4897160	0	4897160	intron_variant	0	0.477014	6E-12	11.2218487496164	""	0.015122306	[0.011-0.019] unit increase	Affymetrix [93095623] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126154475	rs9375414	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	High light scatter reticulocyte count	408,112 British individuals		6q22.32	NCOA7	NCOA7	""	""	ENSG00000111912			rs9375414-A	rs9375414	0	9375414	intron_variant	0	0.40258	3E-18	17.5228787452803	""	0.019624408	[0.015-0.024] unit increase	Affymetrix [93095623] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126223944	rs4897160	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Serum uric acid levels	343,836 European ancestry individuals, 129,405 East Asian ancestry individuals		6q22.32	""	NCOA7	""	""	ENSG00000111912			rs4897160-A	rs4897160	0	4897160	intron_variant	0	NR	2E-16	15.698970004336	""	0.0145	[0.011-0.018] unit increase	Affymetrix, Illumina [20535231] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126223944	rs4897160	2019-10-29	31578528	Tin A	2019-10-02	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/31578528	Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.	Urate levels	174,111 European, East Asian, African American, South Asian and Hispanic ancestry men, 172,102 European, East Asian, African American, South Asian and Hispanic ancestry women		6q22.32	NR	NCOA7	""	""	ENSG00000111912			rs4897160-A	rs4897160	0	4897160	intron_variant	0	0.476	4E-6	5.39794000867204	(men)	0.0228	[0.013-0.032] mg/dL increase	Affymetrix, Illumina [8249849] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126214624	rs11154334	2019-03-07	30578418	Giri A	2018-12-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30578418	Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.	Systolic blood pressure	365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals	299,024 European ancestry individuals, 17,277 individuals	6q22.32	NCOA7	NCOA7	""	""	ENSG00000111912			rs11154334-A	rs11154334	0	11154334	intron_variant	0	0.6055	1E-15	15	""	0.2205	[0.17-0.27] mmHg decrease	Affymetrix [NR] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126221008	rs11154336	2022-08-24	35762941	Plotnikov D	2022-06-01	Invest Ophthalmol Vis Sci	www.ncbi.nlm.nih.gov/pubmed/35762941	High Blood Pressure and Intraocular Pressure: A Mendelian Randomization Study.	Systolic blood pressure	526,001 European ancestry individuals		6q22.32	""	NCOA7	""	""	ENSG00000111912			rs11154336-A	rs11154336	0	11154336	intron_variant	0	NR	5E-12	11.301029995664	""	0.2475	[0.18-0.32] unit increase	NR [NR] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126223944	rs4897160	2020-06-17	32327693	Oskarsson GR	2020-04-23	Commun Biol	www.ncbi.nlm.nih.gov/pubmed/32327693	Predicted loss and gain of function mutations in ACO1 are associated with erythropoiesis.	Hemoglobin levels	684,122 European ancestry individuals		6q22.32	NCOA7	NCOA7	""	""	ENSG00000111912			rs4897160-A	rs4897160	0	4897160	intron_variant	0	""	2E-11	10.698970004336	""	0.015	[NR] unit increase	Affymetrix, Illumina [43000000] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126179111	rs6920965	2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	High light scatter reticulocyte count	170,761 European ancestry individuals		6q22.32	NCOA7	NCOA7	""	""	ENSG00000111912			rs6920965-A	rs6920965	0	6920965	intron_variant	0	0.397	7E-9	8.15490195998574	""	0.02120631	[0.014-0.028] unit increase	Affymetrix [~ 2500000] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126223944	rs4897160	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Hemoglobin	408,112 British individuals		6q22.32	NCOA7	NCOA7	""	""	ENSG00000111912			rs4897160-A	rs4897160	0	4897160	intron_variant	0	0.477008	6E-11	10.2218487496164	""	0.014371591	[0.01-0.019] unit increase	Affymetrix [93095623] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126223944	rs4897160	2019-10-29	31578528	Tin A	2019-10-02	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/31578528	Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.	Urate levels	288,649 European ancestry individuals, 125,725 East Asian ancestry individuals, 33,671 African American individuals, 9,037 South Asian ancestry individuals, 608 Hispanic individuals		6q22.32	NCOA7	NCOA7	""	""	ENSG00000111912			rs4897160-A	rs4897160	0	4897160	intron_variant	0	0.47	2E-14	13.698970004336	""	0.0238	[0.018-0.03] mg/dL increase	Affymetrix, Illumina [8249849] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126154475	rs9375414	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Immature fraction of reticulocytes	408,112 British individuals		6q22.32	NCOA7	NCOA7	""	""	ENSG00000111912			rs9375414-A	rs9375414	0	9375414	intron_variant	0	0.402581	2E-11	10.698970004336	""	0.015244481	[0.011-0.02] unit increase	Affymetrix [93095623] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126166867	rs6922416	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	High light scatter reticulocyte percentage of red cells	408,112 British individuals		6q22.32	NCOA7	NCOA7	""	""	ENSG00000111912			rs6922416-T	rs6922416	0	6922416	intron_variant	0	0.395203	6E-17	16.2218487496164	""	0.018905142	[0.014-0.023] unit increase	Affymetrix [93095623] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126223944	rs4897160	2019-10-29	31578528	Tin A	2019-10-02	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/31578528	Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.	Urate levels	288,649 European ancestry individuals		6q22.32	NCOA7	NCOA7	""	""	ENSG00000111912			rs4897160-A	rs4897160	0	4897160	intron_variant	0	0.4828	2E-14	13.698970004336	""	0.029735	[0.022-0.037] mg/dL increase	Affymetrix, Illumina [8217339] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126221008	rs11154336	2022-08-04	35710981	Liu H	2022-06-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35710981	Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease.	Estimated glomerular filtration rate (creatinine)	1,205,871 European ancestry individuals, 168,300 East Asian ancestry individuals, 63,553 African ancestry individuals, 23,509 Hispanic or Latin American individuals, 22,103 African American individuals, 21,791 Central Asian or South Asian ancestry individuals, 1,502 Middle Eastern ancestry individuals, 939 other admixed ancestry individuals, 602 Native American ancestry individuals, 150 Asian ancestry individuals, 339 individuals		6q22.32	""	NCOA7	""	""	ENSG00000111912			rs11154336-A	rs11154336	0	11154336	intron_variant	0	0.473	1E-13	13	""	7.403	z score increase	Affymetrix, Illumina [12653804] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126166867	rs6922416	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Reticulocyte fraction of red cells	408,112 British individuals		6q22.32	NCOA7	NCOA7	""	""	ENSG00000111912			rs6922416-T	rs6922416	0	6922416	intron_variant	0	0.395228	1E-13	13	""	0.016865494	[0.012-0.021] unit increase	Affymetrix [93095623] (imputed)	N
rs9385388	6	126215296	T	C	0.403579	1.45116628601e-55	-0.010600695562	0.000675090768973	88	6	126154475	rs9375414	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Reticulocyte count	408,112 British individuals		6q22.32	NCOA7	NCOA7	""	""	ENSG00000111912			rs9375414-A	rs9375414	0	9375414	intron_variant	0	0.402587	1E-15	15	""	0.018157413	[0.014-0.023] unit increase	Affymetrix [93095623] (imputed)	N
rs951901	12	58398365	A	C	0.33499	6.68873540984e-09	-0.00567562754421	0.000978799731755	152	12	58460909	rs4760364	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		12q14.1	Intergenic	RN7SKP65 - LINC02403	ENSG00000262776	ENSG00000257541	""	88849	20766	rs4760364-A	rs4760364	0	4760364	intergenic_variant	1	0.6749	6E-18	17.2218487496164	(MTAG)	0.0152	[0.012-0.019] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs951901	12	58398365	A	C	0.33499	6.68873540984e-09	-0.00567562754421	0.000978799731755	152	12	58454271	rs12578279	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability (MTAG)	670,471 European ancestry individuals		12q14.1	Intergenic	RN7SKP65 - LINC02403	ENSG00000262776	ENSG00000257541	""	82211	27404	rs12578279-C	rs12578279	0	12578279	intergenic_variant	1	0.6713	5E-19	18.301029995664	(MTAG)	0.017	[0.013-0.021] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs951901	12	58398365	A	C	0.33499	6.68873540984e-09	-0.00567562754421	0.000978799731755	152	12	58454271	rs12578279	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Self-reported math ability	564,698 European ancestry individuals		12q14.1	Intergenic	RN7SKP65 - LINC02403	ENSG00000262776	ENSG00000257541	""	82211	27404	rs12578279-G	rs12578279	0	12578279	intergenic_variant	1	0.3287	1E-16	16	""	0.0171	[0.013-0.021] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs951901	12	58398365	A	C	0.33499	6.68873540984e-09	-0.00567562754421	0.000978799731755	152	12	58360500	rs7954291	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		12q14.1	""	ATP23 - RN7SKP65	ENSG00000166896	ENSG00000262776	""	7569	11248	rs7954291-?	rs7954291	0	7954291	upstream_gene_variant	1	NR	2E-9	8.69897000433602	""		""	NR [6307410] (imputed)	N
rs951901	12	58398365	A	C	0.33499	6.68873540984e-09	-0.00567562754421	0.000978799731755	152	12	58412978	rs7139165	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		12q14.1	""	RN7SKP65 - LINC02403	ENSG00000262776	ENSG00000257541	""	40918	68697	rs7139165-A	rs7139165	0	7139165	intergenic_variant	1	0.703	1E-11	11	(conditional-joint)	0.0108	[0.0077-0.0139] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs951901	12	58398365	A	C	0.33499	6.68873540984e-09	-0.00567562754421	0.000978799731755	152	12	58398365	rs951901	2022-08-30	32193382	Cole JB	2020-03-19	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/32193382	Comprehensive genomic analysis of dietary habits in UK Biobank identifies hundreds of genetic associations.	Added salt consumption	448,890 European ancestry individuals		12q14.1	""	RN7SKP65 - LINC02403	ENSG00000262776	ENSG00000257541	""	26305	83310	rs951901-C	rs951901	0	951901	intergenic_variant	1	0.342429	2E-8	7.69897000433602	""	0.0123009	[0.008-0.0166] unit increase	NR [NR] (imputed)	N
rs951901	12	58398365	A	C	0.33499	6.68873540984e-09	-0.00567562754421	0.000978799731755	152	12	58356391	rs10783860	2022-08-05	35835914	Watanabe K	2022-07-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35835914	Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.	Insomnia	593,724 European ancestry cases, 1,771,286 European ancestry controls		12q14.1	""	ATP23 - RN7SKP65	ENSG00000166896	ENSG00000262776	""	3460	15357	rs10783860-T	rs10783860	0	10783860	upstream_gene_variant	1	NR	2E-8	7.69897000433602	""	0.006	[0.004-0.008] unit increase	Illumina [10713943] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18459377	rs12459368	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Medication use (beta blocking agents)	31,700 European ancestry cases, 192,324 European ancestry controls, 20,367 East Asian ancestry cases, 158,359 East Asian ancestry controls		19p13.11	""	PGPEP1	""	""	ENSG00000130517			rs12459368-G	rs12459368	0	12459368	intron_variant	0	NR	7E-10	9.15490195998574	""	0.0443	[0.03-0.058] unit decrease	Affymetrix, Illumina [15248280] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18449238	rs9636202	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Mean arterial pressure	360,863 European ancestry individuals, 145,502 East Asian ancestry individuals		19p13.11	""	RN7SL513P - PGPEP1	ENSG00000239821	ENSG00000130517	""	4855	2170	rs9636202-A	rs9636202	0	9636202	regulatory_region_variant	1	NR	1E-11	11	""	0.0141	[0.01-0.0182] unit decrease	Affymetrix, Illumina [20537389] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18460956	rs113230003	2019-02-06	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Body mass index	approximately 458,000 European ancestry individuals		19p13.11	""	PGPEP1	""	""	ENSG00000130517			rs113230003-?	rs113230003	0	113230003	intron_variant	0	NR	4E-20	19.397940008672	""		""	NR [~ 8900000] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18449238	rs9636202	2021-07-27	34187846	Ong JS	2021-06-29	Gut	www.ncbi.nlm.nih.gov/pubmed/34187846	Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett's oesophagus and provides insights into clinical heterogeneity in reflux diagnosis.	Gastroesophageal reflux disease	129,080 European ancestry cases, 473,524 European ancestry controls	462,753 cases, 1,127,474 controls	19p13.11	PGPEP1	RN7SL513P - PGPEP1	ENSG00000239821	ENSG00000130517	""	4855	2170	rs9636202-G	rs9636202	0	9636202	regulatory_region_variant	1	0.73	2E-10	9.69897000433602	""	0.035	unit increase	NR [2324712] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18460956	rs113230003	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Cardiovascular disease	approximately 459,000 European ancestry individuals		19p13.11	""	PGPEP1	""	""	ENSG00000130517			rs113230003-?	rs113230003	0	113230003	intron_variant	0	NR	2E-8	7.69897000433602	""		""	NR [~ 8900000] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18467398	rs12984770	2019-11-05	30239722	Pulit SL	2018-09-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/30239722	Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry.	Body mass index	434,794 European ancestry female individuals		19p13.11		PGPEP1	""	""	ENSG00000130517			rs12984770-A	rs12984770	0	12984770	intron_variant	0	0.7311	6E-17	16.2218487496164	""	0.0182	[0.014-0.023] unit increase	NR [~ 27400000] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18469017	rs12986231	2019-11-04	30239722	Pulit SL	2018-09-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/30239722	Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry.	Waist-hip ratio	697,734 European ancestry individuals		19p13.11		PGPEP1	""	""	ENSG00000130517			rs12986231-T	rs12986231	0	12986231	intron_variant	0	0.7288	2E-11	10.698970004336	""	0.015	[0.011-0.019] unit increase	NR [~ 27400000] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18471610	rs35343344	2019-11-26	31689377	Wootton RE	2019-11-06	Psychol Med	www.ncbi.nlm.nih.gov/pubmed/31689377	Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study.	Lifetime smoking index	462,690 European ancestry individuals		19p13.11	""	PGPEP1	""	""	ENSG00000130517			rs35343344-C	rs35343344	0	35343344	intron_variant	0	0.733	9E-9	8.04575749056068	""	0.013	[0.0091-0.0169] unit increase	Affymetrix [up to 90000000] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18471610	rs35343344	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	Reaction time	330,069 European ancestry individuals		19p13.11	NR	PGPEP1	""	""	ENSG00000130517			rs35343344-?	rs35343344	0	35343344	intron_variant	0	NR	4E-6	5.39794000867204	""	0.0080797	[0.0047-0.0115] unit decrease	Affymetrix [805426] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18449238	rs9636202	2017-03-17	27089181	Okbay A	2016-04-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/27089181	Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.	Life satisfaction	166,205 European ancestry individuals		19p13.11	NR	RN7SL513P - PGPEP1	ENSG00000239821	ENSG00000130517	""	4855	2170	rs9636202-A	rs9636202	0	9636202	regulatory_region_variant	1	0.262	7E-6	5.15490195998574	""	0.0183	[0.01-0.026] unit increase	Affymetrix, Illumina, Perlegen [at least 5170349] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18449238	rs9636202	2019-06-25	30804565	Jansen PR	2019-02-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30804565	Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.	Morningness	434,835 European ancestry individuals		19p13.11	""	RN7SL513P - PGPEP1	ENSG00000239821	ENSG00000130517	""	4855	2170	rs9636202-A	rs9636202	0	9636202	regulatory_region_variant	1	0.2653	4E-8	7.39794000867204	""	0.013	[0.0091-0.0169] unit decrease	Affymetrix, Illumina [11597492] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18449238	rs9636202	2019-04-15	30696823	Jones SE	2019-01-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/30696823	Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms.	Chronotype	449,734  European ancestry individuals	248,098 European ancestry individuals	19p13.11	LSM4, PGPEP1	RN7SL513P - PGPEP1	ENSG00000239821	ENSG00000130517	""	4855	2170	rs9636202-G	rs9636202	0	9636202	regulatory_region_variant	1	0.7338	4E-11	10.397940008672	""	1.026341	""	Affymetrix [11880941] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18454825	rs17724992	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Systolic blood pressure	340,159 European ancestry individuals, 145,505 East Asian ancestry individuals		19p13.11	""	PGPEP1	""	""	ENSG00000130517			rs17724992-G	rs17724992	0	17724992	intron_variant	0	NR	7E-12	11.1549019599857	""	0.0139	[0.01-0.0178] unit decrease	Affymetrix, Illumina [20537302] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18455657	rs66978877	2019-05-02	30487518	Takeuchi F	2018-11-28	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/30487518	Interethnic analyses of blood pressure loci in populations of East Asian and European descent.	Mean arterial pressure	130,777 Japanese ancestry individuals	53,008 East Asian individuals, 105,253 European ancestry individuals	19p13.11	NR	PGPEP1	""	""	ENSG00000130517			rs66978877-T	rs66978877	0	66978877	intron_variant	0	0.5414	4E-6	5.39794000867204	(East Asian)	0.2075	[0.12-0.3] unit increase	Illumina [6200000] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18455657	rs66978877	2019-05-02	30487518	Takeuchi F	2018-11-28	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/30487518	Interethnic analyses of blood pressure loci in populations of East Asian and European descent.	Hypertension	22,566 Japanese ancestry cases, 28,226 Japanese ancestry controls	8,809 East Asian ancestry cases, 13,663 East Asian ancestry controls, 105,253 European ancestry individuals	19p13.11	NR	PGPEP1	""	""	ENSG00000130517			rs66978877-T	rs66978877	0	66978877	intron_variant	0	0.5458	5E-9	8.30102999566398	(East Asian)	0.0661	[0.044-0.088] unit increase	Illumina [6200000] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18455657	rs66978877	2019-05-02	30487518	Takeuchi F	2018-11-28	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/30487518	Interethnic analyses of blood pressure loci in populations of East Asian and European descent.	Systolic blood pressure	130,777 Japanese ancestry individuals	53,008 East Asian individuals, 105,253 European ancestry individuals	19p13.11	NR	PGPEP1	""	""	ENSG00000130517			rs66978877-T	rs66978877	0	66978877	intron_variant	0	0.5414	9E-6	5.04575749056068	(East Asian)	0.2847	[0.16-0.41] unit increase	Illumina [6200000] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18455657	rs66978877	2022-03-07	34910505	van der Meer D	2021-12-15	Sci Adv	www.ncbi.nlm.nih.gov/pubmed/34910505	The genetic architecture of human cortical folding.	Vertex-wise cortical thickness	33,748 European ancestry individuals		19p13.11	""	PGPEP1	""	""	ENSG00000130517			rs66978877-C	rs66978877	0	66978877	intron_variant	0	0.24	2E-13	12.698970004336	""	7.32	z score increase	Affymetrix [9061022] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18455657	rs66978877	2022-03-07	34910505	van der Meer D	2021-12-15	Sci Adv	www.ncbi.nlm.nih.gov/pubmed/34910505	The genetic architecture of human cortical folding.	Vertex-wise sulcal depth	33,748 European ancestry individuals		19p13.11	""	PGPEP1	""	""	ENSG00000130517			rs66978877-C	rs66978877	0	66978877	intron_variant	0	0.24	7E-35	34.1549019599857	""	12.32	z score increase	Affymetrix [9061022] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18459377	rs12459368	2019-09-23	31501611	Karlsson T	2019-09-09	Nat Med	www.ncbi.nlm.nih.gov/pubmed/31501611	Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease.	Predicted visceral adipose tissue	325,153 British ancestry individuals		19p13.11	NR	PGPEP1	""	""	ENSG00000130517			rs12459368-G	rs12459368	0	12459368	intron_variant	0	0.2672	1E-12	12	""	0.019853132	[0.014-0.025] unit decrease	Affymetrix [10549349] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18459377	rs12459368	2022-11-23	35164939	van der Meer D	2022-02-11	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35164939	Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology.	Brain morphology (MOSTest)	33,735 white British ancestry individuals		19p13.11	""	PGPEP1	""	""	ENSG00000130517			rs12459368-?	rs12459368	0	12459368	intron_variant	0	NR	1E-14	14	""		""	NR [9061072] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18459377	rs12459368	2019-06-21	31015401	Wu Y	2019-04-23	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/31015401	Genome-wide association study of medication-use and associated disease in the UK Biobank.	Medication use (beta blocking agents)	31,700 European ancestry cases, 192,324 European ancestry controls		19p13.11	PGPEP1	PGPEP1	""	""	ENSG00000130517			rs12459368-G	rs12459368	0	12459368	intron_variant	0	0.26695	5E-8	7.30102999566398	""	0.050655983	[0.032-0.069] unit decrease	Affymetrix [7288503] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18459377	rs12459368	2021-12-15	34560273	Shadrin AA	2021-09-21	Neuroimage	www.ncbi.nlm.nih.gov/pubmed/34560273	Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.	Cortical surface area	35,657 White British ancestry individuals		19p13.11	NR	PGPEP1	""	""	ENSG00000130517			rs12459368-G	rs12459368	0	12459368	intron_variant	0	0.2698	7E-17	16.1549019599857	""		""	NR [9056863] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18459377	rs12459368	2022-03-07	34910505	van der Meer D	2021-12-15	Sci Adv	www.ncbi.nlm.nih.gov/pubmed/34910505	The genetic architecture of human cortical folding.	Vertex-wise cortical surface area	33,748 European ancestry individuals		19p13.11	""	PGPEP1	""	""	ENSG00000130517			rs12459368-G	rs12459368	0	12459368	intron_variant	0	0.25	1E-17	17	""	8.57	z score increase	Affymetrix [9061022] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18454825	rs17724992	2017-10-27	28892062	Akiyama M	2017-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28892062	Genome-wide association study identifies 112 new loci for body mass index in the Japanese population.	Body mass index	up to 72,390 Japanese ancestry women, up to 85,894 Japanese ancestry men	up to 10,048 Japanese ancestry women, up to 5,098 Japanese ancestry men, up to 181,999 European ancestry women, up to 140,155 European ancestry controls	19p13.11	PGPEP1	PGPEP1	""	""	ENSG00000130517			rs17724992-G	rs17724992	0	17724992	intron_variant	0	0.27	4E-12	11.397940008672	""	0.017	[0.013-0.021] unit decrease	Illumina [6108953] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18454825	rs17724992	2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	Body mass index (joint analysis main effects and smoking interaction)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	19p13.11	PGPEP1	PGPEP1	""	""	ENSG00000130517			rs17724992-A	rs17724992	0	17724992	intron_variant	0	0.7369	3E-6	5.52287874528034	""		""	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18460956	rs113230003	2018-01-29	29212778	van der Harst P	2017-12-06	Circ Res	www.ncbi.nlm.nih.gov/pubmed/29212778	Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.	Coronary artery disease	34,541 cases, 261,984 controls	88,192 cases, 162,544 controls	19p13.11	PGPEP1	PGPEP1	""	""	ENSG00000130517			rs113230003-A	rs113230003	0	113230003	intron_variant	0	0.269	6E-6	5.22184874961636	""	0.033	[0.019-0.047] unit decrease	Affymetrix [7947838] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18460956	rs113230003	2018-07-09	29691431	Tikkanen E	2018-04-24	Sci Rep	www.ncbi.nlm.nih.gov/pubmed/29691431	Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank.	Hand grip strength	334,825 British ancestry individuals		19p13.11	PGPEP1	PGPEP1	""	""	ENSG00000130517			rs113230003-A	rs113230003	0	113230003	intron_variant	0	0.2596	2E-11	10.698970004336	""	0.002	[0.0014-0.0026] unit increase	Affymetrix [15275733] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18460956	rs113230003	2021-01-26	32376654	Richardson TG	2020-05-06	BMJ	www.ncbi.nlm.nih.gov/pubmed/32376654	Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study.	Adult body size	453,169 European ancestry individuals	""	19p13.11	PGPEP1	PGPEP1	""	""	ENSG00000130517			rs113230003-G	rs113230003	0	113230003	intron_variant	0	0.739445	1E-15	15	""	0.0126164	[0.0095-0.0157] unit increase	Affymetrix [12370749]	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18460956	rs113230003	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Smoking initiation (ever regular vs never regular) (MTAG)	up to 1,359,002 European ancestry individuals		19p13.11	NR	PGPEP1	""	""	ENSG00000130517			rs113230003-A	rs113230003	0	113230003	intron_variant	0	0.255	1E-12	12	""	0.00902709	[0.0065-0.0115] unit decrease	NR [9732723] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18460956	rs113230003	2020-04-17	31669095	Zhu Z	2019-10-24	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/31669095	Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank.	Body mass index	457,822 European ancestry individuals		19p13.11	NR	PGPEP1	""	""	ENSG00000130517			rs113230003-?	rs113230003	0	113230003	intron_variant	0	NR	3E-20	19.5228787452803	""		""	Affymetrix [~ 8270000] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18460956	rs113230003	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Smoking initiation (ever regular vs never regular)	up to 1,232,091 European ancestry individuals		19p13.11	NR	PGPEP1	""	""	ENSG00000130517			rs113230003-A	rs113230003	0	113230003	intron_variant	0	0.255	1E-10	10	""	0.018876148	[0.013-0.025] unit decrease	NR [~ 10000000] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18454825	rs17724992	2018-12-17	26961502	Wood AR	2016-03-10	Diabetologia	www.ncbi.nlm.nih.gov/pubmed/26961502	Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively.	Body mass index	29,925 British ancestry cases, 89,763 British ancestry controls		19p13.11	PGPEP1	PGPEP1	""	""	ENSG00000130517			rs17724992-A	rs17724992	0	17724992	intron_variant	0	NR	1E-6	6	(additive model)	0.023	[0.013-0.033] unit increase	NR [9288881] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18454825	rs17724992	2018-12-10	29227965	Pilling LC	2017-12-01	Aging (Albany NY)	www.ncbi.nlm.nih.gov/pubmed/29227965	Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.	Parental longevity (combined parental attained age, Martingale residuals)	389,166 British ancestry individuals		19p13.11	PGPEP1	PGPEP1	""	""	ENSG00000130517			rs17724992-A	rs17724992	0	17724992	intron_variant	0	0.733	9E-7	6.04575749056068	""	0.0124	[0.0075-0.0173] unit increase	Affymetrix [11535925] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18454825	rs17724992	2016-01-27	25673413	Locke AE	2015-02-12	Nature	www.ncbi.nlm.nih.gov/pubmed/25673413	Genetic studies of body mass index yield new insights for obesity biology.	Body mass index	up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals	up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals	19p13.11	PGPEP1	PGPEP1	""	""	ENSG00000130517			rs17724992-A	rs17724992	0	17724992	intron_variant	0	0.748	1E-6	6	(EA, men)	0.023	[0.014-0.032] kg/m2 increase	Affymetrix, Illumina [2550021]	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18454825	rs17724992	2016-01-27	25673413	Locke AE	2015-02-12	Nature	www.ncbi.nlm.nih.gov/pubmed/25673413	Genetic studies of body mass index yield new insights for obesity biology.	Body mass index	up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals	up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals	19p13.11	PGPEP1	PGPEP1	""	""	ENSG00000130517			rs17724992-A	rs17724992	0	17724992	intron_variant	0	0.743	8E-9	8.09691001300806	""	0.02	[0.013-0.026] kg/m2 increase	Affymetrix, Illumina [2550021]	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18454825	rs17724992	2016-01-27	25673413	Locke AE	2015-02-12	Nature	www.ncbi.nlm.nih.gov/pubmed/25673413	Genetic studies of body mass index yield new insights for obesity biology.	Body mass index	up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals	up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals	19p13.11	PGPEP1	PGPEP1	""	""	ENSG00000130517			rs17724992-A	rs17724992	0	17724992	intron_variant	0	0.746	3E-8	7.52287874528034	(EA)	0.019	[0.013-0.026] kg/m2 increase	Affymetrix, Illumina [2550021]	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18452195	rs12459965	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Systolic blood pressure	approximately 422,000 European ancestry individuals		19p13.11	""	PGPEP1	""	""	ENSG00000130517			rs12459965-?	rs12459965	0	12459965	intron_variant	0	NR	4E-12	11.397940008672	""		""	NR [~ 8900000] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18454825	rs17724992	2018-09-28	30108127	Hoffmann TJ	2018-08-14	Genetics	www.ncbi.nlm.nih.gov/pubmed/30108127	A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.	Body mass index	315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals	431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals	19p13.11	NR	PGPEP1	""	""	ENSG00000130517			rs17724992-A	rs17724992	0	17724992	intron_variant	0	NR	5E-7	6.30102999566398	""	0.015	[NR] unit increase	Affymetrix [at least 28613428] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18454825	rs17724992	2018-07-24	26426971	Winkler TW	2015-10-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	Body mass index	up to 309,889 European ancestry individuals		19p13.11	NR	PGPEP1	""	""	ENSG00000130517			rs17724992-A	rs17724992	0	17724992	intron_variant	0	0.743708279308239	5E-8	7.30102999566398	""	0.017328002	unit increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N
rs9636202	19	18449238	A	G	0.243539	8.95797957958e-09	-0.00609675202944	0.00106042199977	195	19	18454825	rs17724992	2017-08-10	28443625	Justice AE	2017-04-26	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28443625	Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.	BMI (adjusted for smoking behaviour)	98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men	21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men	19p13.11	PGPEP1	PGPEP1	""	""	ENSG00000130517			rs17724992-A	rs17724992	0	17724992	intron_variant	0	0.7369	5E-6	5.30102999566398	""	0.0174	[0.01-0.0248] kg/m2 increase	Affymetrix, Illumina, Perlegen [up to 2800000] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133343353	rs763646	2021-06-29	32895543	de la Fuente J	2020-09-07	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/32895543	A general dimension of genetic sharing across diverse cognitive traits inferred from molecular data.	Executive function (trail making test B)	78,547 British ancestry individuals		7q33	""	EXOC4	""	""	ENSG00000131558			rs763646-?	rs763646	0	763646	intron_variant	0	NR	1E-10	10	""		""	NR [7857346] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133431038	rs10247014	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		7q33	""	EXOC4	""	""	ENSG00000131558			rs10247014-?	rs10247014	0	10247014	intron_variant	0	NR	2E-14	13.698970004336	""		""	NR [6307410] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133611256	rs10263851	2020-10-23	32665545	van der Meer D	2020-07-14	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/32665545	Understanding the genetic determinants of the brain with MOSTest.	Brain morphology (MOSTest)	26,502 European ancestry individuals		7q33	EXOC4	EXOC4	""	""	ENSG00000131558			rs10263851-?	rs10263851	0	10263851	intron_variant	0	""	1E-9	9	""		""	NR [7428630] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133339343	rs17167210	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		7q33	EXOC4	EXOC4	""	""	ENSG00000131558			rs17167210-A	rs17167210	0	17167210	intron_variant	0	NR	2E-14	13.698970004336	""	0.02312524	[0.017-0.029] unit decrease	Affymetrix [NR]	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133341162	rs2483509	2019-08-05	31168069	Ward J	2019-06-05	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/31168069	The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function.	Mood instability	157,039 European ancestry cases, 206,666 European ancestry controls		7q33	EXOC4	EXOC4	""	""	ENSG00000131558			rs2483509-?	rs2483509	0	2483509	intron_variant	0	NR	2E-8	7.69897000433602	""	0.00646194	[0.0042-0.0087] unit decrease	Affymetrix [NR] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133337635	rs2345941	2020-06-17	32317632	van de Vegte YJ	2020-04-21	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/32317632	Genome-wide association studies and Mendelian randomization analyses for leisure sedentary behaviours.	Leisure sedentary behaviour (computer use)	408,815 European ancestry individuals		7q33	NR	EXOC4	""	""	ENSG00000131558			rs2345941-?	rs2345941	0	2345941	intron_variant	0	""	4E-11	10.397940008672	""	0.014647	[0.01-0.019] unit increase	Affymetrix [19400418] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133611256	rs10263851	2022-11-23	35164939	van der Meer D	2022-02-11	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35164939	Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology.	Brain morphology (MOSTest)	33,735 white British ancestry individuals		7q33	""	EXOC4	""	""	ENSG00000131558			rs10263851-?	rs10263851	0	10263851	intron_variant	0	NR	6E-9	8.22184874961636	""		""	NR [9061072] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133535714	rs6972284	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		7q33	NR	EXOC4	""	""	ENSG00000131558			rs6972284-?	rs6972284	0	6972284	intron_variant	0	NR	2E-7	6.69897000433602	""	5.191	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133618986	rs6954610	2022-08-04	35585065	May-Wilson S	2022-05-18	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/35585065	Large-scale GWAS of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits.	F-sharp flavour liking (derived food-liking factor)	152,547 European ancestry individuals		7q33	""	EXOC4	""	""	ENSG00000131558			rs6954610-G	rs6954610	0	6954610	intron_variant	0	0.5307	4E-9	8.39794000867204	""	0.05253	[0.035-0.07] unit decrease	Affymetrix [9605914] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133618986	rs6954610	2022-08-04	35585065	May-Wilson S	2022-05-18	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/35585065	Large-scale GWAS of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits.	F-strong flavour liking (derived food-liking factor)	153,924 European ancestry individuals		7q33	""	EXOC4	""	""	ENSG00000131558			rs6954610-G	rs6954610	0	6954610	intron_variant	0	0.5307	3E-8	7.52287874528034	""	0.05035	[0.033-0.068] unit decrease	Affymetrix [9535166] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133582973	rs7793739	2020-01-29	31844048	Hill WD	2019-12-16	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/31844048	Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income.	Household income (MTAG)	505,541 British and unknown ancestry individuals		7q33	EXOC4	EXOC4	""	""	ENSG00000131558			rs7793739-T	rs7793739	0	7793739	intron_variant	0	0.4749	5E-9	8.30102999566398	""	0.011861118	[0.0079-0.0158] unit increase	Affymetrix [up to 18485882] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133472662	rs2551023	2022-08-30	32193382	Cole JB	2020-03-19	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/32193382	Comprehensive genomic analysis of dietary habits in UK Biobank identifies hundreds of genetic associations.	Drink temperature	448,817 European ancestry individuals		7q33	""	EXOC4	""	""	ENSG00000131558			rs2551023-A	rs2551023	0	2551023	intron_variant	0	0.529038	3E-12	11.5228787452803	""	0.0148365	[0.011-0.019] unit decrease	NR [NR] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133606158	rs4422723	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		7q33	EXOC4	EXOC4	""	""	ENSG00000131558			rs4422723-A	rs4422723	0	4422723	intron_variant	0	NR	9E-13	12.0457574905607	""	0.020883946	[0.015-0.027] unit decrease	Affymetrix [NR]	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133429058	rs12707117	2022-10-26	36150907	Hatoum AS	2022-07-14	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/36150907	Genome-wide Association Study Shows That Executive Functioning Is Influenced by GABAergic Processes and Is a Neurocognitive Genetic Correlate of Psychiatric Disorders.	Common executive function	427,037 European ancestry individuals		7q33	""	EXOC4	""	""	ENSG00000131558			rs12707117-?	rs12707117	0	12707117	intron_variant	0	NR	2E-26	25.698970004336	""		""	Affymetrix [7391068] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133055603	rs6973256	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		7q33	NR	EXOC4	""	""	ENSG00000131558			rs6973256-T	rs6973256	0	6973256	intron_variant	0	NR	9E-13	12.0457574905607	""	7.145	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133579006	rs201376358	2022-08-04	35585065	May-Wilson S	2022-05-18	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/35585065	Large-scale GWAS of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits.	F-capsicum liking (derived food-liking factor)	157,390 European ancestry individuals		7q33	""	EXOC4	""	""	ENSG00000131558			rs201376358-C	rs201376358	0	201376358	intron_variant	0	0.5265	2E-9	8.69897000433602	""	0.06393	[0.043-0.085] unit decrease	Affymetrix [9610068] (imputed)	N
rs7806694	7	132883293	T	C	0.487078	4.08378836076e-08	-0.00538748317287	0.000981829243446	105	7	133055603	rs6973256	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		7q33	EXOC4	EXOC4	""	""	ENSG00000131558			rs6973256-T	rs6973256	0	6973256	intron_variant	0	NR	1E-10	10	""	0.01915792	[0.013-0.025] unit increase	Affymetrix [NR]	N
rs9853815	3	94092681	C	T	0.241551	4.4082420947e-08	0.00541425910765	0.000989147119433	51	3	94173895	rs17749394	2020-12-04	33208821	Ishida S	2020-11-18	Commun Biol	www.ncbi.nlm.nih.gov/pubmed/33208821	Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota.	Gut microbiota relative abundance (unclassified genus belonging to family Clostridiaceae)	1,068 Japanese ancestry individuals		3q11.2	intergenic	NA - ARMC10P1	""	ENSG00000178660	""		51715	rs17749394-A	rs17749394	0	17749394	intergenic_variant	1	0.06	2E-6	5.69897000433602	(female)	0.475	[0.28-0.67] unit decrease	Illumina [6380737] (imputed)	N
rs9853815	3	94092681	C	T	0.241551	4.4082420947e-08	0.00541425910765	0.000989147119433	51	3	94055820	rs6801125	2019-08-19	31289104	Kawamura Y	2019-07-08	Ann Rheum Dis	www.ncbi.nlm.nih.gov/pubmed/31289104	Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout.	Gout vs. Hyperuricemia	945 Japanese ancestry cases, 1,003 Japanese ancestry controls	1,915 Japanese ancestry cases, 2,146 Japanese ancestry controls	3q11.2	LOC389137	""	""	""	""			rs6801125-C	rs6801125	0	6801125	intergenic_variant	1	""	2E-6	5.69897000433602	""	1.26	[1.15-1.39]	Illumina [569200]	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16967221	rs1156336	2021-11-25	34033851	Cordell HJ	2021-05-22	J Hepatol	www.ncbi.nlm.nih.gov/pubmed/34033851	An international genome-wide meta-analysis of primary biliary cholangitis: novel risk loci and candidate drugs.	Primary biliary cholangitis	8,021 European ancestry cases, 16,489 European ancestry controls, 2,495 East Asian ancestry cases, 4,283 East Asian ancestry controls		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs1156336-A	rs1156336	0	1156336	intron_variant	0	NR	7E-12	11.1549019599857	""	0.136385	[0.097-0.175] unit decrease	NR [2787054] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16959652	rs983545	2022-04-11	28240269	Suhre K	2017-02-27	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/28240269	Connecting genetic risk to disease end points through the human blood plasma proteome.	C-C motif chemokine 17 levels	997 European ancestry individuals	338 Greater Middle Eastern (Middle Eastern, North African or Persian), South Asian ancestry, Asian ancestry individuals	3p24.3	""	PLCL2	""	""	ENSG00000154822			rs983545-A	rs983545	0	983545	intron_variant	0	NR	2E-12	11.698970004336	(EA)	0.3198	[0.23-0.41] unit increase	Affymetrix [509946]	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16961265	rs9876137	2022-11-17	36329257	Lee CJ	2022-11-03	Commun Biol	www.ncbi.nlm.nih.gov/pubmed/36329257	Phenome-wide analysis of Taiwan Biobank reveals novel glycemia-related loci and genetic risks for diabetes.	Red blood cell count	76,086 Taiwanese ancestry individuals		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs9876137-?	rs9876137	0	9876137	intron_variant	0	NR	1E-20	20	""	0.0198082	unit decrease	NR [5925277] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16955259	rs1372072	2016-09-12	26394269	Cordell HJ	2015-09-22	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/26394269	International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways.	Primary biliary cholangitis	2,764 European ancestry cases, 10,475 European ancestry controls	3,716 European ancestry cases,  4,261 European ancestry controls	3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs1372072-A	rs1372072	0	1372072	intron_variant	0	0.38	4E-8	7.39794000867204	""	1.2	NR	Illumina [1143634] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16972211	rs1459132 x rs2014490	2020-07-28	32450446	Wang H	2020-04-29	Neurobiol Aging	www.ncbi.nlm.nih.gov/pubmed/32450446	Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease.	Total PHF-tau (SNP x SNP interaction)	1,285 individuals		3p24.3	NR x NR	No mapped genes x PLCL2	""	""	""			rs1459132-? x rs2014490-?	rs1459132 x rs2014490	0		intergenic_variant x intron_variant		NR	3E-13	12.5228787452803	""		""	Affymetrix, Illumina [279409] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16972211	rs2014490	2020-06-04	32296059	Han Y	2020-04-15	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/32296059	Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma.	Asthma	84,492 European ancestry cases, 2,149 African American cases, 606 Hispanic cases, 1,239 Japanese ancestry cases, 437,036 European ancestry controls, 6,055 African American controls, 792 Hispanic controls, 3,976 Japanese ancestry controls	NR	3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs2014490-G	rs2014490	0	2014490	intron_variant	0	0.65	8E-10	9.09691001300806	""		""	NR [> 9500000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16955259	rs1372072	2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs1372072-A	rs1372072	0	1372072	intron_variant	0	0.37	2E-8	7.69897000433602	""	1.2	[1.12-1.27]	Illumina [507467]	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16972211	rs2014490	2020-06-04	32296059	Han Y	2020-04-15	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/32296059	Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma.	Asthma	64,538 European ancestry cases, 239,321 European ancestry controls	NR	3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs2014490-G	rs2014490	0	2014490	intron_variant	0	0.65256	9E-10	9.04575749056067	""	1.0392638	[1.02653101253782-1.05215464668184]	NR [9572556] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16961265	rs9876137	2021-11-25	34033851	Cordell HJ	2021-05-22	J Hepatol	www.ncbi.nlm.nih.gov/pubmed/34033851	An international genome-wide meta-analysis of primary biliary cholangitis: novel risk loci and candidate drugs.	Primary biliary cholangitis	8,021 European ancestry cases, 16,489 European ancestry controls		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs9876137-G	rs9876137	0	9876137	intron_variant	0	NR	8E-11	10.0969100130081	""	0.143579	[0.1-0.19] unit increase	NR [5054572] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16924440	rs2278609	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Neuroticism	449,484 European ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs2278609-T	rs2278609	0	2278609	intron_variant	0	NR	5E-9	8.30102999566398	""	5.838	z score decrease	Affymetrix [10847151] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16924440	rs2278609	2019-05-02	30867560	Hill WD	2019-03-13	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/30867560	Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.	General factor of neuroticism	270,059 British ancestry individuals		3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs2278609-T	rs2278609	0	2278609	intron_variant	0	NR	2E-8	7.69897000433602	""	0.0097604	[0.0064-0.0132] unit increase	Affymetrix [18485882] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16897913	rs6442652	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Red blood cell count	408,112 British individuals		3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs6442652-T	rs6442652	0	6442652	intron_variant	0	0.404599	4E-12	11.397940008672	""	0.017919688	[0.013-0.023] unit increase	Affymetrix [93095623] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16908186	rs6766037	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Basophil count	408,112 British individuals		3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs6766037-G	rs6766037	0	6766037	intron_variant	0	0.2181	2E-50	49.698970004336	""	0.04020344	[0.035-0.045] unit decrease	Affymetrix [93095623] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16911330	rs9852648	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Eosinophil counts	approximately 440,000 European ancestry individuals		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs9852648-?	rs9852648	0	9852648	intron_variant	0	NR	2E-25	24.698970004336	""		""	NR [~ 8900000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16911330	rs9852648	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Eosinophil counts	408,112 British individuals		3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs9852648-G	rs9852648	0	9852648	intron_variant	0	0.21842	2E-21	20.698970004336	""	0.025484255	[0.02-0.031] unit decrease	Affymetrix [93095623] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16908186	rs6766037	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Monocyte count	349,856 European ancestry individuals, 95,119 East Asian ancestry individuals		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs6766037-G	rs6766037	0	6766037	intron_variant	0	NR	1E-8	8	""	0.0154	[0.01-0.021] unit decrease	Affymetrix, Illumina [20531031] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16911330	rs9852648	2022-09-13	35935937	Hoglund J	2022-07-22	Front Immunol	www.ncbi.nlm.nih.gov/pubmed/35935937	Gene-Based Variant Analysis of Whole-Exome Sequencing in Relation to Eosinophil Count.	Eosinophil counts	365,954 British ancestry individuals		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs9852648-G	rs9852648	0	9852648	intron_variant	0	0.382	4E-11	10.397940008672	""	0.03	[0.022-0.038] unit decrease	Affymetrix [6661079] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16908186	rs6766037	2020-09-23	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Basophil percentage of white cells	408,112 British individuals		3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs6766037-G	rs6766037	0	6766037	intron_variant	0	0.218113	7E-49	48.1549019599857	""	0.039579988	[0.034-0.045] unit decrease	Affymetrix [93095623] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16908518	rs7613595	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Basophil count	577,663 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs7613595-C	rs7613595	0	7613595	intron_variant	0	0.19357	2E-45	44.698970004336	""		""	Affymetrix, Illumina [19905671] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16908518	rs7613595	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Basophil count	474,001 European ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs7613595-C	rs7613595	0	7613595	intron_variant	0	0.217603	2E-48	47.698970004336	""	0.036371	[0.032-0.041] SD unit decrease	Affymetrix, Illumina [50036608] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16924440	rs2278609	2021-12-13	34469753	Kachuri L	2021-08-26	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/34469753	Genetic determinants of blood-cell traits influence susceptibility to childhood acute lymphoblastic leukemia.	Basophil count	234,678 European ancestry individuals	100,513 European ancestry individuals	3p24.3	""	PLCL2	""	""	ENSG00000154822			rs2278609-T	rs2278609	0	2278609	intron_variant	0	0.782	1E-11	11	""		""	Affymetrix [10369434] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16924440	rs2278609	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Depressed affect	357,957 European ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs2278609-?	rs2278609	0	2278609	intron_variant	0	NR	9E-9	8.04575749056068	""	0.01622	[0.011-0.022] unit increase	Affymetrix [10847151] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16897913	rs6442652	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Mean corpuscular volume	408,112 British individuals		3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs6442652-T	rs6442652	0	6442652	intron_variant	0	0.404571	6E-11	10.2218487496164	""	0.0178238	[0.014-0.022] unit decrease	Affymetrix [93095623] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16908186	rs6766037	2021-12-14	34594039	Sakaue S	2021-09-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/34594039	A cross-population atlas of genetic associations for 220 human phenotypes.	Eosinophil counts	349,856 European ancestry individuals, 93,063 East Asian ancestry individuals		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs6766037-G	rs6766037	0	6766037	intron_variant	0	NR	3E-18	17.5228787452803	""	0.0182	[0.014-0.022] unit decrease	Affymetrix, Illumina [20529668] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16924440	rs2278609	2020-05-29	32231276	Cai N	2020-03-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/32231276	Minimal phenotyping yields genome-wide association signals of low specificity for major depression.	Neuroticism	274,107 British ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs2278609-C	rs2278609	0	2278609	intron_variant	0	0.216	6E-10	9.22184874961636	""	0.01191	[0.0081-0.0157] unit increase	NR [8968716] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16924440	rs2278609	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Neuroticism	approximately 372,000 European ancestry individuals		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs2278609-?	rs2278609	0	2278609	intron_variant	0	NR	2E-10	9.69897000433602	""		""	NR [~ 8900000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16908518	rs7613595	2017-08-30	27863252	Astle WJ	2016-11-17	Cell	www.ncbi.nlm.nih.gov/pubmed/27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Sum eosinophil basophil counts	171,771 European ancestry individuals		3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs7613595-C	rs7613595	0	7613595	intron_variant	0	0.2168	3E-10	9.52287874528034	""	0.02728228	[0.019-0.036] unit decrease	Affymetrix [~ 2500000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16911330	rs9852648	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Eosinophil percentage of white cells	408,112 British individuals		3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs9852648-G	rs9852648	0	9852648	intron_variant	0	0.218439	2E-19	18.698970004336	""	0.024108749	[0.019-0.029] unit decrease	Affymetrix [93095623] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16897913	rs6442652	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Mean reticulocyte volume	408,112 British individuals		3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs6442652-T	rs6442652	0	6442652	intron_variant	0	0.404653	7E-12	11.1549019599857	""	0.018085042	[0.013-0.023] unit decrease	Affymetrix [93095623] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16897913	rs6442652	2020-09-18	32888494	Vuckovic D	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Mean corpuscular hemoglobin	408,112 British individuals		3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs6442652-T	rs6442652	0	6442652	intron_variant	0	0.404573	9E-12	11.0457574905607	""	0.017588444	[0.013-0.023] unit decrease	Affymetrix [93095623] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16908518	rs7613595	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Eosinophil counts	583,850 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs7613595-C	rs7613595	0	7613595	intron_variant	0	0.192235	2E-19	18.698970004336	""		""	Affymetrix, Illumina [19872809] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16908518	rs7613595	2020-09-21	32888493	Chen MH	2020-09-01	Cell	www.ncbi.nlm.nih.gov/pubmed/32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Eosinophil counts	474,237 European ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs7613595-C	rs7613595	0	7613595	intron_variant	0	0.217648	3E-22	21.5228787452803	""	0.023265	[0.019-0.028] SD unit decrease	Affymetrix, Illumina [50000174] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16851202	rs748832	2018-01-12	29186694	Lam M	2017-11-28	Cell Rep	www.ncbi.nlm.nih.gov/pubmed/29186694	Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.	Cognitive ability (MTAG)	436,124 European ancestry individuals		3p24.3	ENSG00000229271, PLCL2	PLCL2	""	""	ENSG00000154822			rs748832-?	rs748832	0	748832	intron_variant	0	NR	6E-11	10.2218487496164	""	6.551	z score increase	Affymetrix, Illumina, Perlegen [7333576] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16859710	rs6779302	2019-11-26	31689377	Wootton RE	2019-11-06	Psychol Med	www.ncbi.nlm.nih.gov/pubmed/31689377	Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study.	Lifetime smoking index	462,690 European ancestry individuals		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs6779302-G	rs6779302	0	6779302	intron_variant	0	0.633	1E-9	9	""	0.013	[0.0091-0.0169] unit decrease	Affymetrix [up to 90000000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16846967	rs9881798	2016-07-23	26198764	Goes FS	2015-07-21	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/26198764	Genome-wide association study of schizophrenia in Ashkenazi Jews.	Schizophrenia	592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs9881798-C	rs9881798	0	9881798	intron_variant	0	NR	7E-6	5.15490195998574	""	1.0526316	[NR]	Illumina [7158791] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16870340	rs6773869	2019-05-02	30867560	Hill WD	2019-03-13	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/30867560	Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.	General factor of neuroticism	270,059 British ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs6773869-A	rs6773869	0	6773869	intron_variant	0	NR	3E-9	8.52287874528034	""	0.010319	[0.0069-0.0137] unit increase	Affymetrix [18485882] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16859710	rs6779302	2017-07-18	28530673	Sniekers S	2017-05-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28530673	Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence.	Intelligence	up to 58,799 European ancestry adults, up to 19,509 European ancestry children		3p24.3	DAZL, PLCL2	PLCL2	""	""	ENSG00000154822			rs6779302-T	rs6779302	0	6779302	intron_variant	0	0.368	5E-8	7.30102999566398	""	5.452	z score decrease	Affymetrix, Illumina [12104294] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16845406	rs9858071	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Depressed affect	357,957 European ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs9858071-C	rs9858071	0	9858071	intron_variant	0	NR	3E-10	9.52287874528034	""	0.01607	[0.011-0.021] unit increase	Affymetrix [10847151] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16845144	rs9857592	2019-08-05	31168069	Ward J	2019-06-05	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/31168069	The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function.	Mood instability	157,039 European ancestry cases, 206,666 European ancestry controls		3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs9857592-?	rs9857592	0	9857592	intron_variant	0	NR	1E-8	8	""	0.00724277	[0.0048-0.0097] unit decrease	Affymetrix [NR] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16856682	rs9813513	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken	430,445 European ancestry individuals		3p24.3	Intergenic	PLCL2	""	""	ENSG00000154822			rs9813513-T	rs9813513	0	9813513	intron_variant	0	0.6251	2E-8	7.69897000433602	""	0.0132	[0.0087-0.0177] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16846967	rs9881798	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Neuroticism	449,484 European ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs9881798-A	rs9881798	0	9881798	intron_variant	0	NR	9E-10	9.04575749056067	""	6.123	z score decrease	Affymetrix [10847151] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16875451	rs6804663	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Depressed affect	357,957 European ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs6804663-?	rs6804663	0	6804663	intron_variant	0	NR	3E-8	7.52287874528034	""	0.01349	[0.0087-0.0182] unit increase	Affymetrix [10847151] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16851755	rs6800583	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs6800583-?	rs6800583	0	6800583	intron_variant	0	NR	3E-9	8.52287874528034	""		""	NR [6307410] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16845144	rs9857592	2018-02-01	29255261	Luciano M	2017-12-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29255261	Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.	Neuroticism	329,821 European ancestry individuals	122,867 European ancestry individuals	3p24.3	intergenic	PLCL2	""	""	ENSG00000154822			rs9857592-A	rs9857592	0	9857592	intron_variant	0	0.29212	4E-11	10.397940008672	""	6.613	unit increase	Illumina [18485882] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16859710	rs6779302	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Smoking status	approximately 458,000 European ancestry individuals		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs6779302-?	rs6779302	0	6779302	intron_variant	0	NR	6E-8	7.22184874961636	""		""	NR [~ 8900000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16870340	rs6773869	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Neurociticism	380,506 European ancestry individuals		3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs6773869-A	rs6773869	0	6773869	intron_variant	0	0.358546	4E-12	11.397940008672	""	6.93	z score decrease	NR [10847151] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16872929	rs2084533	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Cigarettes smoked per day (MTAG)	up to 403,928 European ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs2084533-T	rs2084533	0	2084533	intron_variant	0	0.321	5E-13	12.301029995664	""	0.0168791	[0.012-0.021] unit increase	NR [9732723] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16850764	rs55855024	2021-11-02	34446935	Karlsson Linner R	2021-08-26	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/34446935	Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.	Externalizing behaviour (multivariate analysis)	up to 53,293 European ancestry Attention-deficit/hyperactivity disorder individuals, up to 164,684 European ancestry problematic alcohol use individuals, up to 186,875 European ancestry lifetime cannabis use individuals, up to 357,187 European ancestry individuals measuring  reverse-coded age at first sexual intercourse, up to 336,121 European ancestry individuals measuring number of sexual partners, up to 426,379 European ancestry individuals measuring general risk tolerance, up to 1,251,809  European ancestry individuals measuring lifetime smoking initiation		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs55855024-C	rs55855024	0	55855024	intron_variant	0	0.701	6E-13	12.2218487496164	""	0.009	[0.007-0.011] unit decrease	NR [NR] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16851202	rs748832	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Smoking initiation (ever regular vs never regular) (MTAG)	up to 1,359,002 European ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs748832-G	rs748832	0	748832	intron_variant	0	0.371	2E-15	14.698970004336	""	0.00887082	[0.0067-0.0111] unit increase	NR [9732723] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16843737	rs4684303	2020-01-09	23823483	Rhee EP	2013-07-02	Cell Metab	www.ncbi.nlm.nih.gov/pubmed/23823483	A genome-wide association study of the human metabolome in a community-based cohort.	Metabolite levels	2,076 European ancestry individuals		3p24.3	DAZL	NA - PLCL2	""	ENSG00000154822	""		421	rs4684303-?	rs4684303	0	4684303	intergenic_variant	1	NR	1E-6	6	(symmetric dimethylarginine)	0.23778309	[0.14-0.33] unit increase	Affymetrix [at least 2500000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16850764	rs55855024	2022-09-14	35879402	Deak JD	2022-07-25	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35879402	Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci.	Opioid use disorder (MTAG)	15,251 European ancestry cases, 538,935 European ancestry controls, 5,435 African ancestry cases, 79,442 African ancestry controls		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs55855024-?	rs55855024	0	55855024	intron_variant	0	NR	8E-9	8.09691001300806	""	5.73	Z score increase	Affymetrix, Illumina [NR] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16865845	rs9882532	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs9882532-T	rs9882532	0	9882532	intron_variant	0	0.6368	2E-17	16.698970004336	""	0.0124	[0.0095-0.0153] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16862873	rs9846711	2019-09-04	31374203	Lam M	2019-08-01	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/31374203	Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy)	328,917 individuals with educational attainment measurements, 107,207 individuals with cognitive ability measurements, 77,096 European ancestry schizophrenia cases, 43,456 European ancestry controls		3p24.3	intergenic	PLCL2	""	""	ENSG00000154822			rs9846711-?	rs9846711	0	9846711	intron_variant	0	NR	4E-12	11.397940008672	""	0.014301584	[0.01-0.018] unit decrease	NR [7306098]	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16845144	rs9857592	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Neuroticism	523,783 European ancestry individuals	59,206 European ancestry individuals	3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs9857592-A	rs9857592	0	9857592	intron_variant	0	0.288176654877006	6E-10	9.22184874961636	""	0.013563293	[0.0093-0.0179] unit increase	NR [NR]	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16851202	rs748832	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs748832-A	rs748832	0	748832	intron_variant	0	0.6314	2E-20	19.698970004336	""	0.0100718	[0.0079-0.0122] unit increase	Illumina [10675380] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16872541	rs6442647	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Positive affect	410,603 European ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs6442647-A	rs6442647	0	6442647	intron_variant	0	0.290903082649891	5E-8	7.30102999566398	""	0.0070368894	[0.0045-0.0096] unit increase	NR [NR]	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16851202	rs748832	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Smoking initiation (ever regular vs never regular)	up to 1,232,091 European ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs748832-G	rs748832	0	748832	intron_variant	0	0.371	7E-11	10.1549019599857	""	0.017214172	[0.012-0.022] unit increase	NR [~ 10000000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16865845	rs9882532	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		3p24.3	Intergenic	PLCL2	""	""	ENSG00000154822			rs9882532-T	rs9882532	0	9882532	intron_variant	0	0.6368	6E-21	20.2218487496164	(MTAG)	0.0128	[0.01-0.016] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16872929	rs2084533	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Smoking behaviour (cigarettes smoked per day)	up to 377,334 European ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs2084533-T	rs2084533	0	2084533	intron_variant	0	0.321	7E-10	9.15490195998574	""	0.016117558	[0.011-0.021] unit increase	NR [~ 10000000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16856682	rs9813513	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Highest math class taken (MTAG)	811,539 European ancestry individuals		3p24.3	Intergenic	PLCL2	""	""	ENSG00000154822			rs9813513-T	rs9813513	0	9813513	intron_variant	0	0.6251	1E-14	14	(MTAG)	0.0131	[0.0098-0.0164] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16851202	rs748832	2021-05-19	33082346	Xu K	2020-10-20	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/33082346	Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals.	Smoking initiation	842,717 European ancestry individuals		3p24.3	DAZL, PLCL2	PLCL2	""	""	ENSG00000154822			rs748832-G	rs748832	0	748832	intron_variant	0	""	1E-8	8	""	1.021	[NR]	Affymetrix [up to 79000000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16851202	rs748832	2018-01-12	29186694	Lam M	2017-11-28	Cell Rep	www.ncbi.nlm.nih.gov/pubmed/29186694	Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.	Cognitive ability	107,207 European ancestry individuals		3p24.3	ENSG00000229271	PLCL2	""	""	ENSG00000154822			rs748832-?	rs748832	0	748832	intron_variant	0	NR	1E-7	7	""	5.288	z score increase	Affymetrix, Illumina [7357080] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16866253	rs9867227	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Neuroticism	449,484 European ancestry individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs9867227-A	rs9867227	0	9867227	intron_variant	0	NR	5E-10	9.30102999566398	""	6.225	z score increase	Affymetrix [10847151] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16859710	rs6779302	2017-07-18	28530673	Sniekers S	2017-05-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/28530673	Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence.	Intelligence	up to 58,799 European ancestry adults, up to 19,509 European ancestry children		3p24.3	DAZL, PLCL2	PLCL2	""	""	ENSG00000154822			rs6779302-T	rs6779302	0	6779302	intron_variant	0	0.368	5E-8	7.30102999566398	(Adults)	5.452	z score decrease	Affymetrix, Illumina [12104294] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16870340	rs6773869	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Well-being spectrum (multivariate analysis)	2,083,151 European ancestry individuals	287,239 European ancestry individuals	3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs6773869-G	rs6773869	0	6773869	intron_variant	0	0.353408990639354	2E-9	8.69897000433602	""	0.0057391976	[0.0039-0.0076] unit increase	NR [NR]	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16872541	rs6442647	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Depressive symptoms	1,067,913 European ancestry individuals	228,033 European ancestry individuals	3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs6442647-A	rs6442647	0	6442647	intron_variant	0	0.290903082649891	4E-8	7.39794000867204	""	0.005835455	[0.0037-0.0079] unit increase	NR [NR]	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16851202	rs748832	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs748832-A	rs748832	0	748832	intron_variant	0	NR	2E-10	9.69897000433602	""	0.019265153	[0.013-0.025] unit increase	Affymetrix [NR]	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16866253	rs9867227	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Feeling fed-up	374,971 European ancestry individuals		3p24.3	DAZL	PLCL2	""	""	ENSG00000154822			rs9867227-A	rs9867227	0	9867227	intron_variant	0	0.28261	5E-8	7.30102999566398	""	5.47	z score increase	NR [10847151] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16868616	rs1866862	2022-09-27	35396580	Trubetskoy V	2022-04-08	Nature	www.ncbi.nlm.nih.gov/pubmed/35396580	Mapping genomic loci implicates genes and synaptic biology in schizophrenia.	Schizophrenia	53,386 European ancestry cases, 77,258 European ancestry controls, 14,004 East Asian ancestry cases, 16,757 East Asian ancestry controls, 6,152 African American cases, 3,918 African American controls, 1,234 Latino cases, 3,090 Latino controls	1,979 European ancestry cases, 142,626 European ancestry controls	3p24.3	""	PLCL2	""	""	ENSG00000154822			rs1866862-A	rs1866862	0	1866862	intron_variant	0	0.602	7E-11	10.1549019599857	""	0.95199	[0.94-0.97]	Affymetrix [7585078] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16851202	rs748832	2019-03-28	30643251	Liu M	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643251	Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.	Age of smoking initiation (MTAG)	up to 931,815 European ancestry  individuals		3p24.3	NR	PLCL2	""	""	ENSG00000154822			rs748832-G	rs748832	0	748832	intron_variant	0	0.378	4E-8	7.39794000867204	""	0.00823471	[0.0053-0.0112] unit decrease	NR [9732723] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16856682	rs9813513	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		3p24.3	Intergenic	PLCL2	""	""	ENSG00000154822			rs9813513-T	rs9813513	0	9813513	intron_variant	0	0.6311	9E-13	12.0457574905607	(MTAG)	0.017	[0.012-0.022] unit increase	Affymetrix, Illumina [7100000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16868616	rs1866862	2021-12-23	33693626	Jamieson SE	2021-03-09	Clin Infect Dis	www.ncbi.nlm.nih.gov/pubmed/33693626	Common and rare genetic variants that could contribute to severe otitis media in an Australian Aboriginal population.	Otitis media	21 Martu ancestry cases, 370 Martu ancestry controls		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs1866862-A	rs1866862	0	1866862	intron_variant	0	0.37	3E-6	5.52287874528034	""		""	Illumina [6724284] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16870340	rs6773869	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs6773869-A	rs6773869	0	6773869	intron_variant	0	0.6344	5E-17	16.301029995664	(conditional-joint)	0.0122	[0.0093-0.0151] unit increase	Affymetrix, Illumina [10000000] (imputed)	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16851202	rs748832	2022-04-05	34855049	Pasman JA	2021-12-02	Behav Genet	www.ncbi.nlm.nih.gov/pubmed/34855049	Genetic Risk for Smoking: Disentangling Interplay Between Genes and Socioeconomic Status.	Educational attainment	451,800 European or unknown ancestry individuals		3p24.3	""	PLCL2	""	""	ENSG00000154822			rs748832-?	rs748832	0	748832	intron_variant	0	NR	4E-8	7.39794000867204	""		""	NR [1300000]	N
rs9872237	3	16957332	T	G	0.352883	4.89434523908e-11	0.0064744178482	0.000984834920384	43	3	16870340	rs6773869	2021-09-08	33859377	Thorp JG	2021-04-15	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/33859377	Symptom-level modelling unravels the shared genetic architecture of anxiety and depression.	Anxiety	at least 23,606 European ancestry cases, at least 113,351 European ancestry controls	624,615 European ancestry cases, 1,310,854 European ancestry controls	3p24.3	PLCL2	PLCL2	""	""	ENSG00000154822			rs6773869-A	rs6773869	0	6773869	intron_variant	0	0.3519	2E-14	13.698970004336	""	0.018303616	[0.013-0.024] unit decrease	NR [9417325] (imputed)	N
rs17560772	16	7235901	G	A	0.345924	2.53765854513e-10	0.00607490199419	0.000960508143623	172	16	7251756	rs2346605	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Cognitive performance (MTAG)	402,382 European ancestry individuals		16p13.3	Intergenic	RBFOX1	""	""	ENSG00000078328			rs2346605-C	rs2346605	0	2346605	intron_variant	0	0.333	1E-8	8	(MTAG)	0.0138	[0.0091-0.0185] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs17560772	16	7235901	G	A	0.345924	2.53765854513e-10	0.00607490199419	0.000960508143623	172	16	7249472	rs12709186	2018-09-17	29844566	Davies G	2018-05-29	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29844566	Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.	General cognitive ability	up to 300,486 European ancestry individuals		16p13.3	RBFOX1	RBFOX1	""	""	ENSG00000078328			rs12709186-A	rs12709186	0	12709186	intron_variant	0	NR	4E-8	7.39794000867204	""	5.47	z-score decrease	Affymetrix, Illumina [at least 2500000] (imputed)	N
rs17560772	16	7235901	G	A	0.345924	2.53765854513e-10	0.00607490199419	0.000960508143623	172	16	7261347	rs12709190	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		16p13.3	""	RBFOX1	""	""	ENSG00000078328			rs12709190-T	rs12709190	0	12709190	intron_variant	0	0.679	1E-7	7	""	0.00595634	[0.0038-0.0082] unit increase	Illumina [10675380] (imputed)	N
rs17560772	16	7235901	G	A	0.345924	2.53765854513e-10	0.00607490199419	0.000960508143623	172	16	7249472	rs12709186	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		16p13.3	""	RBFOX1	""	""	ENSG00000078328			rs12709186-A	rs12709186	0	12709186	intron_variant	0	0.3236	1E-9	9	""	0.0091	[0.0062-0.012] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs17560772	16	7235901	G	A	0.345924	2.53765854513e-10	0.00607490199419	0.000960508143623	172	16	7249472	rs12709186	2018-11-12	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (MTAG)	1,311,438 European ancestry individuals		16p13.3	Intergenic	RBFOX1	""	""	ENSG00000078328			rs12709186-A	rs12709186	0	12709186	intron_variant	0	0.3236	3E-11	10.5228787452803	(MTAG)	0.0093	[0.0066-0.012] unit decrease	Affymetrix, Illumina [7100000] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667392	rs3785234	2018-07-19	29728651	Li X	2018-04-27	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/29728651	Common variants on 6q16.2, 12q24.31 and 16p13.3 are associated with major depressive disorder.	Major depressive disorder	84,847 European ancestry cases,  241,266 European ancestry controls, 5,303 Han Chinese ancestry cases, 5,337 Han Chinese ancestry controls	2,659 European ancestry cases, 17,237 European ancestry controls	16p13.3	RBFOX1	RBFOX1	""	""	ENSG00000078328			rs3785234-T	rs3785234	0	3785234	intron_variant	0	0.624	2E-8	7.69897000433602	""	1.035	[NR]	Affymetrix, Illumina [at least 1235109] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7666664	rs55997507	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Feeling worry	372,869 European ancestry individuals		16p13.3	RBFOX1	RBFOX1	""	""	ENSG00000078328			rs55997507-C	rs55997507	0	55997507	intron_variant	0	0.396351	1E-10	10	""	6.437	unit increase	NR [10847151] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7657432	rs4616299	2019-09-02	31263887	Adams MJ	2019-07-01	Int J Epidemiol	www.ncbi.nlm.nih.gov/pubmed/31263887	Factors associated with sharing e-mail information and mental health survey participation in large population cohorts.	Mental health study participation (completed survey)	122,647 British ancestry cases, 248,781 British ancestry controls		16p13.3	RBFOX1	RBFOX1	""	""	ENSG00000078328			rs4616299-G	rs4616299	0	4616299	intron_variant	0	0.4	1E-8	8	""	0.0063466	[0.0042-0.0085] unit decrease	NR [16367095] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7666842	rs11077203	2018-02-01	29255261	Luciano M	2017-12-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29255261	Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.	Neuroticism	329,821 European ancestry individuals	122,867 European ancestry individuals	16p13.3	intergenic	RBFOX1	""	""	ENSG00000078328			rs11077203-A	rs11077203	0	11077203	intron_variant	0	0.60965	8E-11	10.0969100130081	""	6.504	unit increase	Illumina [18485882] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7666402	rs7198928	2018-07-11	29700475	Wray NR	2018-04-26	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29700475	Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.	Depression	135,458 European ancestry cases, 344,901 European ancestry controls		16p13.3	RBFOX1	RBFOX1	""	""	ENSG00000078328			rs7198928-T	rs7198928	0	7198928	intron_variant	0	0.62	1E-8	8	""	1.03	[1.02-1.04]	NR [9622763] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7666407	rs9925434	2022-11-18	34924174	Mitchell BL	2021-11-02	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/34924174	The Australian Genetics of Depression Study: New Risk Loci and Dissecting Heterogeneity Between Subtypes.	Depression	13,318 European ancestry cases, 12,684 European ancestry controls, 246,363 cases, 561,190 controls		16p13.3	""	RBFOX1	""	""	ENSG00000078328			rs9925434-?	rs9925434	0	9925434	intron_variant	0	NR	9E-12	11.0457574905607	""	0.0112	unit decrease	Illumina [7617771] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667392	rs3785234	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Well-being spectrum (multivariate analysis)	2,083,151 European ancestry individuals	287,239 European ancestry individuals	16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs3785234-T	rs3785234	0	3785234	intron_variant	0	0.62081044399491	2E-14	13.698970004336	""	0.0072290096	[0.0054-0.0091] unit increase	NR [NR]	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7666402	rs7198928	2019-03-19	30718901	Howard DM	2019-02-04	Nat Neurosci	www.ncbi.nlm.nih.gov/pubmed/30718901	Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.	Depression	118,811 European ancestry cases, 327,427 European ancestry controls, 127,552 cases, 233,763 controls	414,055 European ancestry cases, 892,299 European ancestry controls	16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs7198928-T	rs7198928	0	7198928	intron_variant	0	0.6159	4E-23	22.397940008672	""	1.022	[1.018-1.027]	NR [8098588] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7666088	rs11646221	2022-04-05	34855049	Pasman JA	2021-12-02	Behav Genet	www.ncbi.nlm.nih.gov/pubmed/34855049	Genetic Risk for Smoking: Disentangling Interplay Between Genes and Socioeconomic Status.	Educational attainment	451,800 European or unknown ancestry individuals		16p13.3	""	RBFOX1	""	""	ENSG00000078328			rs11646221-?	rs11646221	0	11646221	intron_variant	0	NR	1E-11	11	""		""	NR [1300000]	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667538	rs3785232	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Neuroticism	449,484 European ancestry individuals		16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs3785232-T	rs3785232	0	3785232	intron_variant	0	NR	8E-15	14.0969100130081	""	7.763	z score increase	Affymetrix [10847151] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667538	rs3785232	2019-02-08	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Neuroticism	approximately 372,000 European ancestry individuals		16p13.3	""	RBFOX1	""	""	ENSG00000078328			rs3785232-?	rs3785232	0	3785232	intron_variant	0	NR	5E-12	11.301029995664	""		""	NR [~ 8900000] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7666088	rs11646221	2018-09-12	29942086	Savage JE	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942086	Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.	Intelligence	269,867 European ancestry individuals		16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs11646221-T	rs11646221	0	11646221	intron_variant	0	NR	2E-10	9.69897000433602	""	6.399	z-score increase	Affymetrix, Illumina [9295118] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667332	rs11077206	2020-10-07	32606422	Wu Y	2020-06-30	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/32606422	Multi-trait analysis for genome-wide association study of five psychiatric disorders.	Depressive symptoms (MTAG)	955,012 individuals		16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs11077206-?	rs11077206	0	11077206	intron_variant	0	""	4E-9	8.39794000867204	""		""	NR [520857]	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667228	rs3785235	2022-09-07	35898629	Yin B	2022-07-11	Front Psychiatry	www.ncbi.nlm.nih.gov/pubmed/35898629	Shared Genetics and Causality Between Decaffeinated Coffee Consumption and Neuropsychiatric Diseases: A Large-Scale Genome-Wide Cross-Trait Analysis and Mendelian Randomization Analysis.	Decaffeinated coffee consumption and/or neuroticism	64,717 decaffeinated coffee drinking cases, 380,060 individuals with neuroticism measurements, 264,954 controls		16p13.3	""	RBFOX1	""	""	ENSG00000078328			rs3785235-?	rs3785235	0	3785235	intron_variant	0	NR	1E-11	11	""		""	NR [NR]	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667332	rs11077206	2020-08-17	31926635	Coleman JRI	2019-11-01	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/31926635	The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls.	Bipolar disorder or major depressive disorder	164,933 European ancestry major depressive disorder cases, 20,352 European ancestry bipolar disorder cases, 439,741 European ancestry controls		16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs11077206-C	rs11077206	0	11077206	intron_variant	0	NR	5E-10	9.30102999566398	""	1.03	[1.02-1.04]	NR [NR] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7666664	rs55997507	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Worry	348,219 European ancestry individuals		16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs55997507-G	rs55997507	0	55997507	intron_variant	0	NR	3E-10	9.52287874528034	""	0.01558	[0.011-0.02] unit decrease	Affymetrix [10847151] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667228	rs3785235	2021-09-08	33859377	Thorp JG	2021-04-15	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/33859377	Symptom-level modelling unravels the shared genetic architecture of anxiety and depression.	Anxiety	at least 23,606 European ancestry cases, at least 113,351 European ancestry controls	624,615 European ancestry cases, 1,310,854 European ancestry controls	16p13.3	RBFOX1	RBFOX1	""	""	ENSG00000078328			rs3785235-A	rs3785235	0	3785235	intron_variant	0	0.3757	2E-9	8.69897000433602	""	0.014009373	[0.0088-0.0192] unit decrease	NR [9417325] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667392	rs3785234	2018-02-27	29292387	Turley P	2018-01-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29292387	Multi-trait analysis of genome-wide association summary statistics using MTAG.	Depressive symptoms	354,862 European ancestry individuals		16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs3785234-T	rs3785234	0	3785234	intron_variant	0	0.6131	5E-9	8.30102999566398	""	0.0143	[0.0096-0.019] unit increase	Illumina [NR] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667392	rs3785234	2018-02-27	29292387	Turley P	2018-01-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29292387	Multi-trait analysis of genome-wide association summary statistics using MTAG.	Depressive symptoms (MTAG)	354,862 European ancestry individuals		16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs3785234-T	rs3785234	0	3785234	intron_variant	0	0.6131	6E-9	8.22184874961636	""	0.0127	[0.0084-0.017] unit increase	Illumina [NR] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7670326	rs7184911	2022-07-01	35361970	Okbay A	2022-03-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/35361970	Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.	Educational attainment	3,037,499 European ancestry individuals		16p13.3	""	RBFOX1	""	""	ENSG00000078328			rs7184911-A	rs7184911	0	7184911	intron_variant	0	0.5722	8E-13	12.0969100130081	""	0.00758205	[0.0055-0.0097] unit increase	Illumina [10675380] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7670326	rs7184911	2022-09-05	35764056	Rao S	2022-06-28	Neuropsychobiology	www.ncbi.nlm.nih.gov/pubmed/35764056	Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.	Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)	20,183 European ancestry ADHD cases, 18,381 European ancestry ASD cases, up to 63,160 European ancestry controls, 269,867 European ancestry individuals with intelligence measurements		16p13.3	""	RBFOX1	""	""	ENSG00000078328			rs7184911-?	rs7184911	0	7184911	intron_variant	0	NR	4E-9	8.39794000867204	""		""	NR [6307410] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7664875	rs9929993	2021-09-24	33349686	Wendt FR	2020-12-21	Nat Hum Behav	www.ncbi.nlm.nih.gov/pubmed/33349686	Multivariate genome-wide analysis of education, socioeconomic status and brain phenome.	Neuroticism conditioned on educational attainment (multi-trait conditioning and joint analysis)	170,911 European ancestry individuals		16p13.3	""	RBFOX1	""	""	ENSG00000078328			rs9929993-?	rs9929993	0	9929993	non_coding_transcript_exon_variant	0	NR	2E-8	7.69897000433602	""		""	NR [NR]	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7665557	rs3785238	2018-02-23	29326435	Hill WD	2018-01-11	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/29326435	A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.	Intelligence (MTAG)	120,934 British ancestry individuals, 127,548 individuals		16p13.3	RBFOX1	RBFOX1	""	""	ENSG00000078328			rs3785238-A	rs3785238	0	3785238	intron_variant	0	NR	4E-9	8.39794000867204	""	0.017861888	[0.012-0.024] unit decrease	Affymetrix [NR]	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7663290	rs7195278	2019-02-06	30595370	Kichaev G	2018-12-27	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/30595370	Leveraging Polygenic Functional Enrichment to Improve GWAS Power.	Educational attainment (years of education)	approximately 455,000 European ancestry individuals		16p13.3	""	RBFOX1	""	""	ENSG00000078328			rs7195278-?	rs7195278	0	7195278	intron_variant	0	NR	2E-12	11.698970004336	""		""	NR [~ 8900000] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667797	rs2191130	2018-10-31	29942085	Nagel M	2018-06-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/29942085	Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.	Depression	688,809 European ancestry individuals		16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs2191130-T	rs2191130	0	2191130	intron_variant	0	NR	1E-9	9	""	6.099	z score increase	Affymetrix [10847151] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7664875	rs9929993	2018-10-19	30038396	Lee JJ	2018-07-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30038396	Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.	Educational attainment (years of education)	up to 1,131,881 European ancestry individuals		16p13.3	""	RBFOX1	""	""	ENSG00000078328			rs9929993-T	rs9929993	0	9929993	non_coding_transcript_exon_variant	0	0.361	3E-12	11.5228787452803	""	0.0102	[0.0073-0.0131] unit decrease	Affymetrix, Illumina [10000000] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667797	rs2191130	2019-01-22	29500382	Nagel M	2018-03-02	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/29500382	Item-level analyses reveal genetic heterogeneity in neuroticism.	Worry too long after an embarrassing experience	367,725 European ancestry individuals		16p13.3	RBFOX1	RBFOX1	""	""	ENSG00000078328			rs2191130-T	rs2191130	0	2191130	intron_variant	0	0.321718	3E-9	8.52287874528034	""	5.95	z score increase	NR [10847151] (imputed)	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667797	rs2191130	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Neuroticism	523,783 European ancestry individuals	59,206 European ancestry individuals	16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs2191130-T	rs2191130	0	2191130	intron_variant	0	0.682655420953353	3E-13	12.5228787452803	""	0.011671352	[0.0085-0.0148] unit increase	NR [NR]	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667797	rs2191130	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Depressive symptoms	1,067,913 European ancestry individuals	228,033 European ancestry individuals	16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs2191130-T	rs2191130	0	2191130	intron_variant	0	0.682655420953353	3E-13	12.5228787452803	""	0.007441718	[0.0054-0.0094] unit increase	NR [NR]	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667797	rs2191130	2020-10-07	32606422	Wu Y	2020-06-30	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/32606422	Multi-trait analysis for genome-wide association study of five psychiatric disorders.	Depressive symptoms	688,809 individuals		16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs2191130-?	rs2191130	0	2191130	intron_variant	0	""	1E-9	9	""		""	NR [11140414]	N
rs9929993	16	7664875	T	C	0.350895	8.03172702381e-10	0.00597864388511	0.000973039168534	173	16	7667797	rs2191130	2019-03-18	30643256	Baselmans BML	2019-01-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/30643256	Multivariate genome-wide analyses of the well-being spectrum.	Life satisfaction	80,852 European ancestry individuals		16p13.3	NR	RBFOX1	""	""	ENSG00000078328			rs2191130-T	rs2191130	0	2191130	intron_variant	0	0.682655420953353	2E-9	8.69897000433602	""	0.009343457	[0.0063-0.0124] unit increase	NR [NR]	N