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\begin{document}

\title[Article Title]{Supplementary Information to: The Ethics of ChatGPT in Medicine and Healthcare: A Systematic Review
on Large Language Models (LLMs)}

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%% GivenName	-> \fnm{Joergen W.}
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\author[1]{\fnm{Joschka} \sur{Haltaufderheide}}

\author*[1]{\fnm{Robert} \sur{Ranisch}}\email{ranisch@uni-potsdam.de}



\affil*[1]{\orgdiv{Juniorprofessorship for Medical Ethics with a focus on Digitization}, \orgname{Faculty for Health Sciences Brandenburg, University of Potsdam}, \orgaddress{\street{Am M\"uhlenberg 9}, \city{Potsdam}, \postcode{14476}, \state{Brandenburg}, \country{Germany}}}

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\section*{Supplementary Note 1: Key concepts for the search}\label{secA1}

\begin{enumerate}
\item LLM are machines which use computational methods, partially under
human supervision, to extract statistical relationships from large
corpora of data such as text documents, databases and websites. This
allows them to predict a number of tokens or words given a certain
input and thereby to generate text that follows the learned statistical
conventions to an extent that most humans find to mimick human language
use.
\item Healthcare is the practice of restoring, maintaining or improving
a physical or mental well-being, including prevention, diagnosis,
treatment or cure of disease or injury. Healthcare is often performed
in structured settings involving the help of trained health professionals
such as medical doctors, nurses etc.
\item Ethical~issues can be defined as a state of affairs in which moral
implications of a given situation cannot be determined without much
reservation, disagreement with regard to the right course of action
exists, or conflicting moral obligations presenting themselves. This
may include a variety of different situations, such as occurrence
of unclear or undetermined benefits, chances, risks or harms, unclear,
undetermined or conflicting views about addressees of moral complaints
as well as situations in which applicable moral principles obviously
should have been considered but weren\textquoteright t. We determined
that that an ethical issue exists whenever it is understood as such.
\end{enumerate}

\section*{Supplementary Note 2: Overview on data extraction fields}\label{secA2}
\begin{enumerate}
\item Bibliographic data {[}author; title; journal/server; funding; coi{]}
\item Article type {[}orientation;type{]}
\item Aims of publication
\item Field of application {[}name of device; device description; anticipated
development; technical intentionality\slash capabilities; technical
limitations; medical domain; applications and outcomes; benchmarks
for comparison; 
\item Value dimension {[}value; normative background; ethical methods{]}
\item Findings {[}user-interactions; concerns; perception of hype/fears;
systemic perspectives{]}
\item Recommendations
\item Implications for practice
\item Future research directions
\end{enumerate}

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