Sample Name	Protocol REF	Parameter Value[instrument]	Parameter Value[manufacturer]	Assay Name	Raw Data File	Comment[Data Repository]	Comment[Data Record Accession]	Comment[Data Record URI]	Protocol REF	Derived Data File	Comment[Data Repository]	Comment[Data Record Accession]	Comment[Data Record URI]	Protocol REF	Derived Data File	Comment[Data Repository]	Comment[Data Record Accession]	Comment[Data Record URI]	Protocol REF	Derived Data File	Comment[Data Repository]	Comment[Data Record Accession]	Comment[Data Record URI]	Factor Value[biological replicate]
K562 cells	ChIP-seq and ChIP-exo library preparation	NextSeq 550	Illumina	1-ChIPexo_Pol2	SRX3480267	NCBI Sequence Read Archvie	SRP116017	https://www.ncbi.nlm.nih.gov/sra/?term=SRP116017	Sequence read alignment and quality control	SRX3480267	NCBI Sequence Read Archvie	SRP116017	https://www.ncbi.nlm.nih.gov/sra/?term=SRP116017	Biological validation	GSE108323_ChIP_exoMerge.bw	Gene Expression Omnibus	GSE108323	https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE108323	RPKM analysis	TableS1_rpkm.xlsx	figshare	doi:10.6084/m9.figshare.c.3971301	https://doi.org/10.6084/m9.figshare.c.3971301	replicate 1
K562 cells	ChIP-seq and ChIP-exo library preparation	NextSeq 550	Illumina	2-ChIPexo_Pol2	SRX3480277	NCBI Sequence Read Archvie	SRP116017	https://www.ncbi.nlm.nih.gov/sra/?term=SRP116017	Sequence read alignment and quality control	SRX3480277	NCBI Sequence Read Archvie	SRP116017	https://www.ncbi.nlm.nih.gov/sra/?term=SRP116017	Biological validation	GSE108323_ChIP_exoMerge.bw	Gene Expression Omnibus	GSE108323	https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE108323	RPKM analysis	TableS1_rpkm.xlsx	figshare	doi:10.6084/m9.figshare.c.3971301	https://doi.org/10.6084/m9.figshare.c.3971301	replicate 2
K562 cells	ChIP-seq and ChIP-exo library preparation	NextSeq 550	Illumina	1-ChIPexo_H2AZ	SRX3480268	NCBI Sequence Read Archvie	SRP116017	https://www.ncbi.nlm.nih.gov/sra/?term=SRP116017	Sequence read alignment and quality control	SRX3480268	NCBI Sequence Read Archvie	SRP116017	https://www.ncbi.nlm.nih.gov/sra/?term=SRP116017	Biological validation	GSE108323_ChIP_exoMerge_H2AZ.bw	Gene Expression Omnibus	GSE108323	https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE108323	RPKM analysis	TableS1_rpkm.xlsx	figshare	doi:10.6084/m9.figshare.c.3971301	https://doi.org/10.6084/m9.figshare.c.3971301	replicate 1
K562 cells	ChIP-seq and ChIP-exo library preparation	NextSeq 550	Illumina	2-ChIPexo_H2AZ	SRX3480275	NCBI Sequence Read Archvie	SRP116017	https://www.ncbi.nlm.nih.gov/sra/?term=SRP116017	Sequence read alignment and quality control	SRX3480275	NCBI Sequence Read Archvie	SRP116017	https://www.ncbi.nlm.nih.gov/sra/?term=SRP116017	Biological validation	GSE108323_ChIP_exoMerge_H2AZ.bw	Gene Expression Omnibus	GSE108323	https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE108323	RPKM analysis	TableS1_rpkm.xlsx	figshare	doi:10.6084/m9.figshare.c.3971301	https://doi.org/10.6084/m9.figshare.c.3971301	replicate 2
K562 cells	ChIP-seq and ChIP-exo library preparation	NextSeq 550	Illumina	1-ChIPexo_H3K4me3	SRX3480269	NCBI Sequence Read Archvie	SRP116017	https://www.ncbi.nlm.nih.gov/sra/?term=SRP116017	Sequence read alignment and quality control	SRX3480269	NCBI Sequence Read Archvie	SRP116017	https://www.ncbi.nlm.nih.gov/sra/?term=SRP116017	Biological validation	GSE108323_ChIP_exoMerge_H3K4me3.bw	Gene Expression Omnibus	GSE108323	https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE108323	RPKM analysis	TableS1_rpkm.xlsx	figshare	doi:10.6084/m9.figshare.c.3971301	https://doi.org/10.6084/m9.figshare.c.3971301	replicate 1
K562 cells	ChIP-seq and ChIP-exo library preparation	NextSeq 550	Illumina	2-ChIPexo_H3K4me3	SRX3480276	NCBI Sequence Read Archvie	SRP116017	https://www.ncbi.nlm.nih.gov/sra/?term=SRP116017	Sequence read alignment and quality control	SRX3480276	NCBI Sequence Read Archvie	SRP116017	https://www.ncbi.nlm.nih.gov/sra/?term=SRP116017	Biological validation	GSE108323_ChIP_exoMerge_H3K4me3.bw	Gene Expression Omnibus	GSE108323	https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE108323	RPKM analysis	TableS1_rpkm.xlsx	figshare	doi:10.6084/m9.figshare.c.3971301	https://doi.org/10.6084/m9.figshare.c.3971301	replicate 2
