{"text_format":"3","workbook":"xls","n_sheets":5,"sheets":["Sheet1-Supp Table 2","Sheet-2 Molecular function","Sheet3- Cellular Function","Sheet4- Molecular Function","Sheet-5 Unkwn function"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Sheet1-Supp Table 2","index":0,"n_rows":10,"n_cols":1,"rows_kept":10,"flags":["formulas_cached_only"]}
["Agrawal et al., 2011, Supplementary Table 3  "]
[]
["In this Spreadsheet we describe Functional classification of potential direct targets of Ubx identified by ChIP-chip. "]
["Targets were categorised in different functional groups manually based on experimental data available in Flybase (gene function summary). "]
[]
["Sheet 2 contains genes classified based on their molecular function"]
["Sheet 3 contains genes classified based on their Cellular function"]
["Sheet 4 contains genes classified based on their Developmental function"]
["Sheet 5 contains genes  which were of unknown or unclassified function"]
["Please note a given gene may be represented in more than one category. "]

{"sheet":"Sheet-2 Molecular function","index":1,"n_rows":200,"n_cols":8,"rows_kept":200,"merged":[[1,3,1,6]],"flags":["formulas_cached_only"]}
[]
[{"$nulls":3}," Classification based on molecular function"]
[]
["Category","Flybase ID","NAME","SYMBOL","Summary of gene function from Flybase","GO_BIOLOGICAL_PROCESS","GO_CELLULAR_COMPONENT","GO_MOLECULAR_FUNCTION"]
["Wnt Signaling"]
[null,"FBgn0000117","armadillo","arm","The gene armadillo is referred to in FlyBase by the symbol Dmel\\arm (CG11579, FBgn0000117). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1785434..1794673. It has the cytological map location 2B14. There is experimental evidence that it has the molecular function</span>: transcription activator activity; protein binding; transcription coactivator activity. There is experimental evidence for 22 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; cell adhesion; positive regulation of cellular biosynthetic process; regulation of developmental process; sensory organ development; positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; stem cell differentiation; reproductive process in a multicellular organism; delamination; cell junction organization. 177 alleles are reported. The phenotypes of these alleles are annotated with 100 unique terms, many of which group under: organ system; adult segment; abdominal ventral denticle belt; embryonic nervous system; female germline cyst; adult mesothoracic segment; embryonic/larval tracheal system; embryonic neuron; external compound sense organ; peripheral nervous system. It has 5 annotated transcripts and 5 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from sequence or structural similarity with MGD:Catnb; MGI:MGI:88276 <newline> cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | non-traceable author statement <newline> neuroblast fate determination ; GO:0007400 | non-traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> oocyte localization during germarium-derived egg chamber formation ; GO:0030720 | traceable author statement <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> heart development ; GO:0007507 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> positive regulation of JNK cascade ; GO:0046330 | traceable author statement <newline> protein localization ; GO:0008104 | traceable author statement <newline> germ-line stem cell division ; GO:0042078 | non-traceable author statement <newline> zonula adherens assembly ; GO:0045186 | traceable author statement <newline> establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement <newline> somatic stem cell maintenance ; GO:0035019 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype <newline> zonula adherens assembly ; GO:0045186 | inferred from mutant phenotype <newline> cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype <newline> cell morphogenesis ; GO:0000902 | inferred from mutant phenotype <newline> ventral furrow formation ; GO:0007370 | inferred from mutant phenotype <newline> neuroblast development ; GO:0014019 | inferred from mutant phenotype <newline> photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> compound eye retinal cell programmed cell death ; GO:0046667 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from direct assay <newline> imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype <newline> delamination ; GO:0060232 | inferred from mutant phenotype <newline> wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | inferred from mutant phenotype <newline> positive regulation of transcription ; GO:0045941 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | inferred from mutant phenotype","zonula adherens ; GO:0005915 | inferred from direct assay <newline> catenin complex ; GO:0016342 | inferred from sequence or structural similarity <newline> adherens junction ; GO:0005912 | non-traceable author statement <newline> catenin complex ; GO:0016342 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | non-traceable author statement <newline> membrane ; GO:0016020 | non-traceable author statement <newline> apicolateral plasma membrane ; GO:0016327 | traceable author statement <newline> adherens junction ; GO:0005912 | inferred from direct assay <newline> adherens junction ; GO:0005912 | traceable author statement <newline> cytoplasm ; GO:0005737 | traceable author statement <newline> spot adherens junction ; GO:0005914 | non-traceable author statement <newline> zonula adherens ; GO:0005915 | non-traceable author statement <newline> zonula adherens ; GO:0005915 | traceable author statement <newline> apical plasma membrane ; GO:0016324 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from physical interaction with pygo <newline> cytoplasm ; GO:0005737 | inferred from direct assay","cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity <newline> protein binding ; GO:0005515 | inferred from physical interaction with Apc2 AND inferred from physical interaction with Mer <newline> alpha-catenin binding ; GO:0045294 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P22265 <newline> transcription activator activity ; GO:0016563 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with Apc2 <newline> transcription coactivator activity ; GO:0003713 | inferred from direct assay"]
[null,"FBgn0003371","shaggy","sgg","The gene shaggy is referred to in FlyBase by the symbol Dmel\\sgg (CG2621, FBgn0003371). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2527983..2571879. It has the cytological map location 3A8-3B1. There is experimental evidence that it has the molecular function</span>: protein kinase activity; kinase activity. There is experimental evidence for 16 unique biological process</span> terms, many of which group under: anatomical structure development; regulation of biological process; reproductive process in a multicellular organism; organ development; learning; regulation of circadian rhythm; multicellular organism reproduction; learning or memory; regionalization; biopolymer modification; circadian rhythm; regulation of developmental process; embryonic pattern specification; olfactory learning; entrainment of circadian clock; regulation of metabolic process. 149 alleles are reported. The phenotypes of these alleles are annotated with 44 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; abdominal ventral denticle belt; nervous system; external compound sense organ; cuticle; larval abdominal segment; embryonic/larval hemocoel. It has 15 annotated transcripts and 15 annotated polypeptides.","synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> circadian rhythm ; GO:0007623 | inferred from mutant phenotype <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype <newline> heart development ; GO:0007507 | non-traceable author statement <newline> protein localization ; GO:0008104 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> negative regulation of Wnt receptor signaling pathway ; GO:0030178 | traceable author statement <newline> blastoderm segmentation ; GO:0007350 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> bristle morphogenesis ; GO:0008407 | non-traceable author statement <newline> circadian rhythm ; GO:0007623 | non-traceable author statement <newline> locomotor rhythm ; GO:0045475 | non-traceable author statement <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from direct assay <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay <newline> regulation of proteolysis ; GO:0030162 | inferred from direct assay <newline> circadian rhythm ; GO:0007623 | traceable author statement <newline> Notch signaling pathway ; GO:0007219 | traceable author statement <newline> regulation of protein import into nucleus ; GO:0042306 | traceable author statement <newline> rhythmic behavior ; GO:0007622 | traceable author statement <newline> regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype <newline> entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype <newline> wing and notum subfield formation ; GO:0035309 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> olfactory learning ; GO:0008355 | inferred from mutant phenotype <newline> habituation ; GO:0046959 | inferred from mutant phenotype <newline> regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype","-","protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity <newline> protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement <newline> kinase activity ; GO:0016301 | inferred from direct assay <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> glycogen synthase kinase 3 activity ; GO:0004696 | non-traceable author statement <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017442 <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR002290, InterPro:IPR008271"]
[null,"FBgn0003415","skuld","skd","The gene skuld is referred to in FlyBase by the symbol Dmel\\skd (CG9936, FBgn0003415). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20987228..21020524. It has the cytological map location 78A2. There is experimental evidence that it has the molecular function</span>: protein binding; RNA polymerase II transcription mediator activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of Wnt receptor signaling pathway; sex comb development; wing disc dorsal/ventral pattern formation; regulation of transcription from RNA polymerase II promoter; embryonic development; cell fate commitment. 44 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; eye disc; mitotic cell cycle; antennal disc; photoreceptor cell; crystal cell; larval mouth. It has 3 annotated transcripts and 3 annotated polypeptides.","cell fate commitment ; GO:0045165 | inferred from genetic interaction with Scr <newline> embryonic development ; GO:0009790 | inferred from mutant phenotype <newline> sex comb development ; GO:0045498 | inferred from genetic interaction with Scr AND inferred from mutant phenotype <newline> transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC_gene:THRAP1; HGNC:22474; OMIM:603808 <newline> transcription from RNA polymerase II promoter ; GO:0006366 | non-traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> positive regulation of Wnt receptor signaling pathway ; GO:0030177 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay <newline> mediator complex ; GO:0016592 | inferred from sequence or structural similarity with HGNC_gene:THRAP1; HGNC:22474; OMIM:603808 <newline> mediator complex ; GO:0016592 | non-traceable author statement <newline> mediator complex ; GO:0016592 | inferred from direct assay","RNA polymerase II transcription mediator activity ; GO:0016455 | inferred from sequence or structural similarity with HGNC_gene:THRAP1; HGNC:22474; OMIM:603808 <newline> RNA polymerase II transcription mediator activity ; GO:0016455 | non-traceable author statement <newline> serine-type endopeptidase activity ; GO:0004252 | NOT non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VW47 <newline> RNA polymerase II transcription mediator activity ; GO:0016455 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VT57"]
[null,"FBgn0016797","frizzled 2","fz2","The gene frizzled 2 is referred to in FlyBase by the symbol Dmel\\fz2 (CG9739, FBgn0016797). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19135998..19228191. It has the cytological map location 75F9-76A3. There is experimental evidence that it has the molecular function</span>: Wnt receptor activity; protein binding; PDZ domain binding; Wnt-protein binding. There is experimental evidence that it is involved in the biological process</span>: female gonad development; cellular component movement; imaginal disc-derived wing margin morphogenesis; receptor-mediated endocytosis; bristle morphogenesis; Wnt receptor signaling pathway; axon extension; salivary gland morphogenesis; Wnt receptor signaling pathway, calcium modulating pathway; synapse organization. 112 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; adult segment; nervous system; adult mesothoracic segment; external compound sense organ; peripheral nervous system; cell component; cuticle; t-bar; embryonic neuron; postsynaptic membrane; neuromuscular junction. It has 4 annotated transcripts and 4 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from direct assay <newline> establishment or maintenance of cell polarity ; GO:0007163 | inferred from sequence or structural similarity <newline> Wnt receptor signaling pathway, calcium modulating pathway ; GO:0007223 | inferred from direct assay <newline> cellular component movement ; GO:0006928 | inferred from mutant phenotype <newline> female gonad development ; GO:0008585 | inferred from mutant phenotype <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> receptor-mediated endocytosis ; GO:0006898 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from sequence or structural similarity <newline> Wnt receptor signaling pathway ; GO:0016055 | non-traceable author statement <newline> axon extension ; GO:0048675 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> synapse organization ; GO:0050808 | inferred from physical interaction with Grip <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype","integral to membrane ; GO:0016021 | non-traceable author statement <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> early endosome ; GO:0005769 | colocalizes_with inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> late endosome ; GO:0005770 | colocalizes_with inferred from direct assay","Wnt receptor activity ; GO:0042813 | inferred from direct assay <newline> Wnt-protein binding ; GO:0017147 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from direct assay <newline> transmembrane receptor activity ; GO:0004888 | inferred from sequence or structural similarity <newline> Wnt receptor activity ; GO:0042813 | non-traceable author statement <newline> PDZ domain binding ; GO:0030165 | inferred from physical interaction with Grip <newline> non-G-protein coupled 7TM receptor activity ; GO:0004926 | inferred from electronic annotation with InterPro:IPR000539"]
[null,"FBgn0020245","tout-velu","ttv","The gene tout-velu is referred to in FlyBase by the symbol Dmel\\ttv (CG10117, FBgn0020245). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10414076..10472826. It has the cytological map location 51A7-51B4. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: decapentaplegic receptor signaling pathway; smoothened signaling pathway; glycosaminoglycan biosynthetic process; regulation of smoothened signaling pathway; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; germ cell migration; Wnt receptor signaling pathway; heparin biosynthetic process; heparan sulfate proteoglycan biosynthetic process. 64 alleles are reported. The phenotypes of these alleles are annotated with: dorsal mesothoracic disc; cuticle; macrochaeta; germline cell; denticle belt. It has one annotated transcript and one annotated polypeptide.","germ cell migration ; GO:0008354 | inferred from mutant phenotype <newline> regulation of smoothened signaling pathway ; GO:0008589 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | non-traceable author statement <newline> heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | inferred from genetic interaction with Ext2 <newline> decapentaplegic receptor signaling pathway ; GO:0008101 | inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | traceable author statement <newline> glycosaminoglycan biosynthetic process ; GO:0006024 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | non-traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | non-traceable author statement <newline> Wnt receptor signaling pathway ; GO:0016055 | inferred from mutant phenotype <newline> heparin biosynthetic process ; GO:0030210 | inferred from mutant phenotype <newline> N-acetylglucosamine metabolic process ; GO:0006044 | inferred from sequence or structural similarity with UniProtKB:O77783 <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from direct assay","integral to membrane ; GO:0016021 | non-traceable author statement <newline> Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> intrinsic to endoplasmic reticulum membrane ; GO:0031227 | inferred from electronic annotation with InterPro:IPR015338","acetylglucosaminyltransferase activity ; GO:0008375 | inferred from sequence or structural similarity with EMBL:AF089748 <newline> acetylglucosaminyltransferase activity ; GO:0008375 | non-traceable author statement <newline> glucuronosyltransferase activity ; GO:0015020 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with Ext2 <newline> N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity ; GO:0050509 | inferred from sequence or structural similarity with UniProtKB:O77783 <newline> glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity ; GO:0050508 | inferred from sequence or structural similarity with UniProtKB:O77783"]
[null,"FBgn0027343","frizzled 3","fz3","The gene frizzled 3 is referred to in FlyBase by the symbol Dmel\\fz3 (CG16785, FBgn0027343). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:664061..677344. It has the cytological map location 1C4. Based on sequence similarity, it is predicted to have molecular function</span>: transmembrane receptor activity; Wnt-protein binding. There is experimental evidence that it is involved in the biological process</span>: establishment or maintenance of cell polarity. 10 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from sequence or structural similarity <newline> establishment or maintenance of cell polarity ; GO:0007163 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from sequence or structural similarity <newline> Wnt receptor signaling pathway ; GO:0016055 | non-traceable author statement <newline> cell surface receptor linked signaling pathway ; GO:0007166 | inferred from electronic annotation with InterPro:IPR000539, InterPro:IPR017981","integral to membrane ; GO:0016021 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000539, InterPro:IPR017981","Wnt-protein binding ; GO:0017147 | inferred from sequence or structural similarity <newline> transmembrane receptor activity ; GO:0004888 | inferred from sequence or structural similarity <newline> Wnt receptor activity ; GO:0042813 | non-traceable author statement <newline> non-G-protein coupled 7TM receptor activity ; GO:0004926 | inferred from electronic annotation with InterPro:IPR000539"]
[null,"FBgn0041604","dally-like","dlp","The gene dally-like is referred to in FlyBase by the symbol Dmel\\dlp (CG32146, FBgn0041604). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14625720..14664716. It has the cytological map location 70E5-70E7. It is reported to have molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; detection of light stimulus involved in visual perception; axon guidance; compound eye development; imaginal disc-derived wing margin morphogenesis; wing disc dorsal/ventral pattern formation; positive regulation of smoothened signaling pathway; Wnt receptor signaling pathway; regulation of imaginal disc growth; segment polarity determination. 39 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; peripheral nervous system; adult mesothoracic segment; external compound sense organ; organ system; nervous system; cuticle; lamina plexus; dorsal thoracic disc; compound cell cluster organ. It has 2 annotated transcripts and 2 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from genetic interaction with dally AND inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> decapentaplegic receptor signaling pathway ; GO:0008101 | non-traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | traceable author statement <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from expression pattern AND inferred from genetic interaction with wg <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> detection of light stimulus involved in visual perception ; GO:0050908 | inferred from mutant phenotype <newline> positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype <newline> regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype","extracellular region ; GO:0005576 | inferred from sequence or structural similarity <newline> proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR001863 <newline> membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001863","protein binding ; GO:0005515 | non-traceable author statement <newline> heparan sulfate proteoglycan binding ; GO:0043395 | inferred from electronic annotation with InterPro:IPR001863"]
[null,"FBgn0046763","-","CG17278","This gene is referred to in FlyBase by the symbol Dmel\\CG17278 (CG17278, FBgn0046763). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16846756..16849885. It has the cytological map location 93B4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: negative regulation of Wnt receptor signaling pathway. 8 alleles are reported. The phenotypes of these alleles are annotated with: adult abdomen; wing blade; wing. It has one annotated transcript and one annotated polypeptide.","negative regulation of Wnt receptor signaling pathway ; GO:0030178 | inferred from genetic interaction with dsh inferred from genetic interaction with sgg","-","-"]
[null,"FBgn0085432","pangolin","pan","The gene pangolin is referred to in FlyBase by the symbol Dmel\\pan (CG34403, FBgn0085432). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:89956..129430. It has the cytological map location 102A3-102A4. There is experimental evidence that it has the molecular function</span>: specific transcriptional repressor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of Wnt receptor signaling pathway; spiracle morphogenesis, open tracheal system; embryonic pattern specification; regulation of hemocyte differentiation; imaginal disc-derived wing morphogenesis; positive regulation of transcription; salivary gland morphogenesis. 44 alleles are reported. The phenotypes of these alleles are annotated with 39 unique terms, many of which group under: organ system; adult segment; late extended germ band embryo; thoracic segment; muscle founder cell; peripheral nervous system; embryonic/larval tracheal system; adult mesothoracic segment; dorsal thoracic disc; spiracle. It has 10 annotated transcripts and 10 annotated polypeptides.","embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from sequence or structural similarity with MGD:Tcf7l2; MGI:MGI:1202879 <newline> segment polarity determination ; GO:0007367 | non-traceable author statement <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> mesodermal cell fate determination ; GO:0007500 | traceable author statement <newline> regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype <newline> spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | non-traceable author statement <newline> regulation of Wnt receptor signaling pathway ; GO:0030111 | inferred from mutant phenotype <newline> negative regulation of Wnt receptor signaling pathway ; GO:0030178 | non-traceable author statement <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> positive regulation of transcription ; GO:0045941 | inferred from mutant phenotype","transcription factor complex ; GO:0005667 | inferred from sequence or structural similarity with MGD:Tcf7l2; MGI:MGI:1202879 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000910"]
[null,"FBgn0250823","gilgamesh","gish","The gene gilgamesh is referred to in FlyBase by the symbol Dmel\\gish (CG6963, FBgn0250823). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12098176..12128094. It has the cytological map location 89B9-89B12. Based on sequence similarity, it is predicted to have molecular function</span>: protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: glial cell migration; protein amino acid phosphorylation; Wnt receptor signaling pathway; spermatogenesis. 49 alleles are reported. The phenotypes of these alleles are annotated with: spermatogonium; eye; photoreceptor cell; ommatidium. It has 9 annotated transcripts and 9 annotated polypeptides.","spermatogenesis ; GO:0007283 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> glial cell migration ; GO:0008347 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay","plasma membrane ; GO:0005886 | inferred from direct assay","protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity <newline> protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with UniProtKB:Q62763 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0261885","osa","osa","The gene osa is referred to in FlyBase by the symbol Dmel\\osa (CG7467, FBgn0261885). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:13513540..13544059. It has the cytological map location 90C1-90C2. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; organ development; regulation of biological process; regulation of metabolic process; regionalization; appendage development; positive regulation of cellular biosynthetic process; segment specification; regulation of epidermal growth factor receptor signaling pathway. 62 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: adult segment; adult mesothoracic segment; peripheral nervous system; organ system; nervous system; thoracic segment; dorsal thoracic disc; external compound sense organ; Malpighian tubule; larval thorax; wing cell. It has 4 annotated transcripts and 4 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from mutant phenotype <newline> photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype <newline> segment specification ; GO:0007379 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from direct assay <newline> positive regulation of transcription, DNA-dependent ; GO:0045893 | inferred from direct assay <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> brahma complex ; GO:0035060 | inferred from direct assay <newline> brahma complex ; GO:0035060 | traceable author statement","DNA binding ; GO:0003677 | non-traceable author statement <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> transcription coactivator activity ; GO:0003713 | contributes_to inferred by curator from GO:0035060"]
[null,"FBgn0037734","trabid","trbd","The gene trabid is referred to in FlyBase by the symbol Dmel\\trbd (CG9448, FBgn0037734). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of Wnt receptor signaling pathway. 5 alleles are reported. The phenotype of these alleles is annotated with: embryonic heart. It has one annotated transcript and one annotated polypeptide. Protein features are: Ovarian tumour, otubain; Zinc finger, RanBP2-type. Gene sequence location is 3R:5531512..5536754.","positive regulation of Wnt receptor signaling pathway ; GO:0030177 | inferred from genetic interaction with wg inferred from genetic interaction with arm","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001876","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001876"]
[null,"FBgn0035142","homeodomain interacting protein kinase","hipk","The gene homeodomain interacting protein kinase is referred to in FlyBase by the symbol Dmel\\hipk (CG17090, FBgn0035142). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: beta-catenin binding; transcription factor binding; protein serine/threonine kinase activity; protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of Wnt receptor signaling pathway; compound eye development; imaginal disc-derived wing margin morphogenesis; protein stabilization; protein amino acid phosphorylation; imaginal disc-derived wing vein morphogenesis; positive regulation of Notch signaling pathway. 33 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; eye disc; eye; intersegmental nerve; eye photoreceptor cell. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain. Gene sequence location is 3L:543070..576065.","protein phosphorylation ; GO:0006468 | non-traceable author statement <newline> positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with Dl inferred from genetic interaction with N inferred from genetic interaction with gro inferred from genetic interaction with H <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> positive regulation of Wnt receptor signaling pathway ; GO:0030177 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> protein stabilization ; GO:0050821 | inferred from mutant phenotype <newline> protein phosphorylation ; GO:0006468 | inferred from direct assay","-","protein kinase activity ; GO:0004672 | non-traceable author statement <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with SGD_LOCUS:YAK1; SGD:S0003677 <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay <newline> beta-catenin binding ; GO:0008013 | inferred from physical interaction with arm <newline> transcription factor binding ; GO:0008134 | inferred from physical interaction with pan <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017442"]
[]
["Notch Signaling"]
[null,"FBgn0004647","Notch","N","The gene Notch is referred to in FlyBase by the symbol Dmel\\N (CG3936, FBgn0004647). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3028905..3066295. It has the cytological map location 3C7-3C9. There is experimental evidence that it has the molecular function</span>: protein binding; specific transcriptional repressor activity; transcription activator activity. There is experimental evidence for 54 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; organ development; regulation of developmental process; sensory organ development; organ morphogenesis; regulation of neurogenesis; cellular component movement; ovarian follicle cell development; regulation of biological process. 653 alleles are reported. The phenotypes of these alleles are annotated with 219 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; adult mesothoracic segment; organ system; external compound sense organ; embryonic nervous system; multi-cell-component structure; primordium; embryonic neuron. It has one annotated transcript and one annotated polypeptide.","stem cell differentiation ; GO:0048863 | inferred from mutant phenotype <newline> regulation of neurogenesis ; GO:0050767 | inferred from mutant phenotype <newline> ectoderm development ; GO:0007398 | traceable author statement <newline> mesoderm development ; GO:0007498 | inferred from mutant phenotype <newline> ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> leg joint morphogenesis ; GO:0035111 | inferred from mutant phenotype <newline> leg segmentation ; GO:0035286 | inferred from mutant phenotype <newline> R8 cell development ; GO:0045463 | traceable author statement <newline> cell adhesion ; GO:0007155 | traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> glial cell fate determination ; GO:0007403 | inferred from mutant phenotype <newline> peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype <newline> germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> muscle cell fate determination ; GO:0007521 | inferred from mutant phenotype <newline> regulation of cardioblast cell fate specification ; GO:0042686 | inferred from mutant phenotype <newline> regulation of growth ; GO:0040008 | inferred from genetic interaction with scrib AND inferred from mutant phenotype <newline> foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype <newline> oocyte localization during germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> anesthesia-resistant memory ; GO:0007615 | NOT inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from mutant phenotype <newline> lateral inhibition ; GO:0046331 | traceable author statement <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype <newline> cell fate specification ; GO:0001708 | traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> anterior/posterior pattern formation ; GO:0009952 | traceable author statement <newline> leg disc morphogenesis ; GO:0007478 | traceable author statement <newline> cell fate commitment ; GO:0045165 | non-traceable author statement <newline> negative regulation of fusion cell fate specification ; GO:0035157 | traceable author statement <newline> negative regulation of terminal cell fate specification, open tracheal system ; GO:0035155 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> imaginal disc growth ; GO:0007446 | traceable author statement <newline> imaginal disc pattern formation ; GO:0007447 | traceable author statement <newline> skeletal muscle tissue development ; GO:0007519 | inferred from mutant phenotype <newline> ovarian follicle cell stalk formation ; GO:0030713 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> germarium-derived egg chamber formation ; GO:0007293 | traceable author statement <newline> germarium-derived female germ-line cyst encapsulation ; GO:0030708 | traceable author statement <newline> morphogenesis of follicular epithelium ; GO:0016333 | non-traceable author statement <newline> oocyte anterior/posterior axis specification ; GO:0007314 | traceable author statement <newline> dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | traceable author statement <newline> establishment of ommatidial planar polarity ; GO:0042067 | non-traceable author statement <newline> cell fate specification ; GO:0001708 | non-traceable author statement <newline> compound eye retinal cell programmed cell death ; GO:0046667 | traceable author statement <newline> second mitotic wave during compound eye morphogenesis ; GO:0016330 | non-traceable author statement <newline> R8 cell differentiation ; GO:0045465 | non-traceable author statement <newline> regulation of R8 cell spacing in compound eye ; GO:0045468 | non-traceable author statement <newline> dorsal/ventral pattern formation, imaginal disc ; GO:0007450 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> lateral inhibition ; GO:0046331 | non-traceable author statement <newline> negative regulation of JNK cascade ; GO:0046329 | non-traceable author statement <newline> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | NOT non-traceable author statement <newline> establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement <newline> crystal cell differentiation ; GO:0042688 | inferred from mutant phenotype <newline> embryonic hemopoiesis ; GO:0035162 | inferred from mutant phenotype <newline> hemocyte proliferation ; GO:0035172 | inferred from mutant phenotype <newline> larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype <newline> R3/R4 cell fate commitment ; GO:0007464 | non-traceable author statement <newline> retinal cell programmed cell death ; GO:0046666 | traceable author statement <newline> wing disc proximal/distal pattern formation ; GO:0007473 | traceable author statement <newline> regulation of crystal cell differentiation ; GO:0042689 | traceable author statement <newline> asymmetric cell division ; GO:0008356 | traceable author statement <newline> ventral cord development ; GO:0007419 | non-traceable author statement <newline> R7 cell differentiation ; GO:0045466 | traceable author statement <newline> regulation of mitotic cell cycle ; GO:0007346 | traceable author statement <newline> lymph gland crystal cell differentiation ; GO:0035170 | traceable author statement <newline> embryonic crystal cell differentiation ; GO:0035165 | traceable author statement <newline> long-term memory ; GO:0007616 | traceable author statement <newline> lymph gland development ; GO:0048542 | inferred from mutant phenotype <newline> negative regulation of compound eye photoreceptor development ; GO:0045316 | inferred from mutant phenotype <newline> positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> compound eye cone cell fate commitment ; GO:0042676 | traceable author statement <newline> compound eye development ; GO:0048749 | non-traceable author statement <newline> compound eye development ; GO:0048749 | traceable author statement <newline> R8 cell fate commitment ; GO:0007460 | traceable author statement <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> heterophilic cell-cell adhesion ; GO:0007157 | inferred from mutant phenotype inferred from direct assay <newline> positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype <newline> lamellocyte differentiation ; GO:0035171 | inferred from mutant phenotype <newline> response to symbiont ; GO:0009608 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype <newline> negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype <newline> epithelial cell type specification, open tracheal system ; GO:0035153 | inferred from mutant phenotype <newline> glial cell migration ; GO:0008347 | inferred from mutant phenotype <newline> glial cell differentiation ; GO:0010001 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from direct assay <newline> positive regulation of S phase of mitotic cell cycle ; GO:0045750 | inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from genetic interaction with klg <newline> R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype <newline> R1/R6 cell differentiation ; GO:0048052 | inferred from mutant phenotype <newline> eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype <newline> regulation of cell differentiation ; GO:0045595 | inferred from mutant phenotype","intracellular ; GO:0005622 | inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> integral to membrane ; GO:0016021 | traceable author statement <newline> integral to plasma membrane ; GO:0005887 | non-traceable author statement <newline> intracellular ; GO:0005622 | non-traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | traceable author statement <newline> subapical complex ; GO:0035003 | inferred from direct assay <newline> adherens junction ; GO:0005912 | inferred from direct assay <newline> cytoplasmic vesicle ; GO:0031410 | colocalizes_with inferred from direct assay <newline> protein complex ; GO:0043234 | inferred from physical interaction with Su(H) <newline> integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR010660, InterPro:IPR011656","transmembrane receptor activity ; GO:0004888 | traceable author statement <newline> receptor activity ; GO:0004872 | non-traceable author statement <newline> transcription activator activity ; GO:0016563 | non-traceable author statement <newline> receptor activity ; GO:0004872 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with dx <newline> transmembrane receptor activity ; GO:0004888 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> protein binding ; GO:0005515 | inferred from physical interaction with shg <newline> transcription activator activity ; GO:0016563 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VVI3 <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9Y0H4 <newline> protein binding ; GO:0005515 | inferred from physical interaction with Su(H) <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097"]
[null,"FBgn0000472","diminutive","dm","The gene diminutive is referred to in FlyBase by the symbol Dmel\\dm (CG10798, FBgn0000472). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3267216..3280049. It has the cytological map location 3D2. There is experimental evidence that it has the molecular function</span>: transcription factor activity; protein binding; DNA binding. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: regulation of biological process; regulation of metabolic process; multicellular organismal development; regulation of growth; embryonic development; cell proliferation; embryonic development ending in birth or egg hatching; cell cycle; regulation of apoptosis; positive regulation of cellular biosynthetic process; anatomical structure development; cellular process; embryonic pattern specification; negative regulation of Notch signaling pathway. 55 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; peripheral nervous system; nervous system; external compound sense organ; female germline cyst; cell cycle; nucleus; thoracic segment; imaginal precursor; intracellular membrane-bounded organelle. It has one annotated transcript and one annotated polypeptide.","regulation of transcription, DNA-dependent ; GO:0006355 | inferred from direct assay <newline> cell proliferation ; GO:0008283 | inferred from expression pattern <newline> embryonic development ending in birth or egg hatching ; GO:0009792 | inferred from expression pattern <newline> positive regulation of cell growth ; GO:0030307 | traceable author statement <newline> positive regulation of growth ; GO:0045927 | traceable author statement <newline> regulation of cell size ; GO:0008361 | traceable author statement <newline> positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement <newline> DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype <newline> cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype <newline> regulation of organ growth ; GO:0046620 | inferred from mutant phenotype <newline> regulation of cell growth ; GO:0001558 | inferred from mutant phenotype <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | traceable author statement <newline> regulation of cell cycle ; GO:0051726 | traceable author statement <newline> positive regulation of transcription ; GO:0045941 | inferred from mutant phenotype <newline> neurogenesis ; GO:0022008 | inferred from genetic interaction with Egfr <newline> embryonic pattern specification ; GO:0009880 | inferred from genetic interaction with Egfr <newline> negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with N <newline> regulation of apoptosis ; GO:0042981 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:L00039 <newline> protein complex ; GO:0043234 | inferred from physical interaction with gro","DNA binding ; GO:0003677 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:L00039 <newline> protein binding ; GO:0005515 | inferred from physical interaction with lid <newline> protein binding ; GO:0005515 | inferred from physical interaction with gro"]
[null,"FBgn0002732","E(spl) region transcript malpha","malpha","The gene E(spl) region transcript m? is referred to in FlyBase by the symbol Dmel\\m? (CG8337, FBgn0002732). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21836615..21837290. It has the cytological map location 96F10. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: sensory organ development; Notch signaling pathway; cell fate specification. 12 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: peripheral nervous system; nervous system; organ system; adult segment; adult mesothoracic segment; eo support cell; sensillum; tormogen cell; integumentary plate; central nervous system; wing margin bristle. It has one annotated transcript and one annotated polypeptide.","Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype <newline> cell fate specification ; GO:0001708 | inferred from mutant phenotype <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement","-","-"]
[null,"FBgn0002733","E(spl) region transcript mbeta","HLHmbeta","The gene E(spl) region transcript m? is referred to in FlyBase by the symbol Dmel\\HLHm? (CG14548, FBgn0002733). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21830648..21831745. It has the cytological map location 96F9. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: negative regulation of transcription from RNA polymerase II promoter. 7 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; wing margin bristle; macrochaeta; anterior crossvein; scutellar bristle; microchaeta; wing vein. It has one annotated transcript and one annotated polypeptide.","negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> negative regulation of transcription ; GO:0016481 | non-traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> compound eye development ; GO:0048749 | traceable author statement","nucleus ; GO:0005634 | inferred by curator from GO:0003677 <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR011598","transcription factor activity ; GO:0003700 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> transcription repressor activity ; GO:0016564 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from direct assay"]
[null,"FBgn0002735","E(spl) region transcript mgamma","HLHmgamma","The gene E(spl) region transcript m? is referred to in FlyBase by the symbol Dmel\\HLHm? (CG8333, FBgn0002735). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21825580..21826421. It has the cytological map location 96F9. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding; transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of transcription; wing disc dorsal/ventral pattern formation. 10 alleles are reported. The phenotypes of these alleles are annotated with: adult thorax; wing margin bristle; macrochaeta; scutellar bristle; microchaeta; wing vein. It has one annotated transcript and one annotated polypeptide.","negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> negative regulation of transcription ; GO:0016481 | non-traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> compound eye development ; GO:0048749 | traceable author statement <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> negative regulation of transcription ; GO:0016481 | inferred from direct assay","nucleus ; GO:0005634 | inferred by curator from GO:0003677 <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR011598","transcription factor activity ; GO:0003700 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> transcription repressor activity ; GO:0016564 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | inferred from direct assay <newline> sequence-specific DNA binding ; GO:0043565 | inferred from direct assay"]
[null,"FBgn0003371","shaggy","sgg","The gene shaggy is referred to in FlyBase by the symbol Dmel\\sgg (CG2621, FBgn0003371). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2527983..2571879. It has the cytological map location 3A8-3B1. There is experimental evidence that it has the molecular function</span>: protein kinase activity; kinase activity. There is experimental evidence for 16 unique biological process</span> terms, many of which group under: anatomical structure development; regulation of biological process; reproductive process in a multicellular organism; organ development; learning; regulation of circadian rhythm; multicellular organism reproduction; learning or memory; regionalization; biopolymer modification; circadian rhythm; regulation of developmental process; embryonic pattern specification; olfactory learning; entrainment of circadian clock; regulation of metabolic process. 149 alleles are reported. The phenotypes of these alleles are annotated with 44 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; abdominal ventral denticle belt; nervous system; external compound sense organ; cuticle; larval abdominal segment; embryonic/larval hemocoel. It has 15 annotated transcripts and 15 annotated polypeptides.","synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> circadian rhythm ; GO:0007623 | inferred from mutant phenotype <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype <newline> heart development ; GO:0007507 | non-traceable author statement <newline> protein localization ; GO:0008104 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> negative regulation of Wnt receptor signaling pathway ; GO:0030178 | traceable author statement <newline> blastoderm segmentation ; GO:0007350 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> bristle morphogenesis ; GO:0008407 | non-traceable author statement <newline> circadian rhythm ; GO:0007623 | non-traceable author statement <newline> locomotor rhythm ; GO:0045475 | non-traceable author statement <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from direct assay <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay <newline> regulation of proteolysis ; GO:0030162 | inferred from direct assay <newline> circadian rhythm ; GO:0007623 | traceable author statement <newline> Notch signaling pathway ; GO:0007219 | traceable author statement <newline> regulation of protein import into nucleus ; GO:0042306 | traceable author statement <newline> rhythmic behavior ; GO:0007622 | traceable author statement <newline> regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype <newline> entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype <newline> wing and notum subfield formation ; GO:0035309 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> olfactory learning ; GO:0008355 | inferred from mutant phenotype <newline> habituation ; GO:0046959 | inferred from mutant phenotype <newline> regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype","-","protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity <newline> protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement <newline> kinase activity ; GO:0016301 | inferred from direct assay <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> glycogen synthase kinase 3 activity ; GO:0004696 | non-traceable author statement <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017442 <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR002290, InterPro:IPR008271"]
[null,"FBgn0011224","hephaestus","heph","The gene hephaestus is referred to in FlyBase by the symbol Dmel\\heph (CG31000, FBgn0011224). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27676704..27819000. It has the cytological map location 100D3-100E1. There is experimental evidence that it has the molecular function</span>: mRNA 3'-UTR binding; translation repressor activity, nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: spermatid development; imaginal disc-derived wing margin morphogenesis; oocyte microtubule cytoskeleton polarization; imaginal disc-derived wing vein morphogenesis; Notch signaling pathway; negative regulation of oskar mRNA translation. 106 alleles are reported. The phenotypes of these alleles are annotated with: macrochaeta; testis; wing; individualization stage spermatid; spermatozoon. It has 22 annotated transcripts and 22 annotated polypeptides.","spermatid development ; GO:0007286 | inferred from mutant phenotype <newline> nuclear mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with NCBI_NP:002810 <newline> Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> negative regulation of oskar mRNA translation ; GO:0007319 | inferred from mutant phenotype <newline> oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay <newline> ribonucleoprotein complex ; GO:0030529 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR006536","poly-pyrimidine tract binding ; GO:0008187 | non-traceable author statement <newline> mRNA binding ; GO:0003729 | inferred from sequence or structural similarity <newline> poly-pyrimidine tract binding ; GO:0008187 | inferred from sequence or structural similarity with NCBI_NP:002810 <newline> mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay <newline> translation repressor activity, nucleic acid binding ; GO:0000900 | inferred from mutant phenotype <newline> nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR012677"]
[null,"FBgn0011591","fringe","fng","The gene fringe is referred to in FlyBase by the symbol Dmel\\fng (CG10580, FBgn0011591). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20918983..20942609. It has the cytological map location 78A1. There is experimental evidence that it has the molecular function</span>: UDP-glycosyltransferase activity; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity; acetylglucosaminyltransferase activity. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; organ morphogenesis; regulation of biological process; leg morphogenesis; sensory organ development; leg segmentation; biopolymer modification; hexose metabolic process; regionalization; appendage development; compound eye development. 66 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; female germline cyst; late extended germ band embryo; nervous system; ectoderm derivative; external compound sense organ; primordium. It has one annotated transcript and one annotated polypeptide.","imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> dorsal/ventral pattern formation, imaginal disc ; GO:0007450 | inferred from direct assay <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from direct assay <newline> leg joint morphogenesis ; GO:0035111 | inferred from mutant phenotype <newline> leg segmentation ; GO:0035286 | inferred from mutant phenotype <newline> Notch signaling pathway ; GO:0007219 | inferred from direct assay <newline> fucose metabolic process ; GO:0006004 | inferred from direct assay <newline> germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype <newline> regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype <newline> positive regulation of Notch signaling pathway ; GO:0045747 | non-traceable author statement <newline> Notch signaling pathway ; GO:0007219 | traceable author statement <newline> dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | traceable author statement <newline> regulation of Notch signaling pathway ; GO:0008593 | traceable author statement <newline> negative regulation of Notch signaling pathway ; GO:0045746 | non-traceable author statement <newline> regulation of Notch signaling pathway ; GO:0008593 | non-traceable author statement <newline> cell fate specification ; GO:0001708 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from direct assay <newline> oogenesis ; GO:0048477 | traceable author statement <newline> regulation of Notch signaling pathway ; GO:0008593 | inferred from direct assay <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> protein amino acid O-linked glycosylation ; GO:0006493 | inferred from mutant phenotype <newline> fucose metabolic process ; GO:0006004 | inferred from mutant phenotype","Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> Golgi apparatus ; GO:0005794 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | non-traceable author statement <newline> Golgi stack ; GO:0005795 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> Golgi apparatus ; GO:0005794 | traceable author statement <newline> integral to Golgi membrane ; GO:0030173 | inferred from electronic annotation with InterPro:IPR017374","UDP-glycosyltransferase activity ; GO:0008194 | inferred from direct assay <newline> acetylglucosaminyltransferase activity ; GO:0008375 | inferred from direct assay <newline> acetylglucosaminyltransferase activity ; GO:0008375 | non-traceable author statement <newline> acetylglucosaminyltransferase activity ; GO:0008375 | traceable author statement <newline> O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity ; GO:0033829 | inferred from direct assay"]
[null,"FBgn0259176","bunched","bun","The gene bunched is referred to in FlyBase by the symbol Dmel\\bun (CG42281, FBgn0259176). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12456577..12546630. It has the cytological map location 33E5-33E9. Based on sequence similarity, it is predicted to have molecular function</span>: protein homodimerization activity. There is experimental evidence for 13 unique biological process</span> terms, many of which group under: regulation of biological process; anatomical structure development; reproductive process in a multicellular organism; regulation of developmental process; programmed cell death; ovarian follicle cell development; positive regulation of biological process; positive regulation of cell proliferation; regionalization; regulation of anatomical structure size; gland morphogenesis; regulation of apoptosis; negative regulation of Notch signaling pathway. 140 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: external compound sense organ; peripheral nervous system; adult segment; organ system; nervous system; female germline cyst; egg; chorion; thoracic segment; adult mesothoracic segment. It has 8 annotated transcripts and 8 annotated polypeptides.","decapentaplegic receptor signaling pathway ; GO:0008101 | inferred from genetic interaction with dpp <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype <newline> negative regulation of cell fate specification ; GO:0009996 | inferred from mutant phenotype <newline> ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype <newline> negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype <newline> cell fate determination ; GO:0001709 | non-traceable author statement <newline> dorsal appendage formation ; GO:0046843 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> compound eye development ; GO:0048749 | non-traceable author statement <newline> oogenesis ; GO:0048477 | non-traceable author statement <newline> positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype <newline> positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000580","cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | non-traceable author statement","protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000580"]
[null,"FBgn0035142","homeodomain interacting protein kinase","hipk","The gene homeodomain interacting protein kinase is referred to in FlyBase by the symbol Dmel\\hipk (CG17090, FBgn0035142). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: beta-catenin binding; transcription factor binding; protein serine/threonine kinase activity; protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of Wnt receptor signaling pathway; compound eye development; imaginal disc-derived wing margin morphogenesis; protein stabilization; protein amino acid phosphorylation; imaginal disc-derived wing vein morphogenesis; positive regulation of Notch signaling pathway. 33 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; eye disc; eye; intersegmental nerve; eye photoreceptor cell. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain. Gene sequence location is 3L:543070..576065.","protein phosphorylation ; GO:0006468 | non-traceable author statement <newline> positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with Dl inferred from genetic interaction with N inferred from genetic interaction with gro inferred from genetic interaction with H <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> positive regulation of Wnt receptor signaling pathway ; GO:0030177 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> protein stabilization ; GO:0050821 | inferred from mutant phenotype <newline> protein phosphorylation ; GO:0006468 | inferred from direct assay","-","protein kinase activity ; GO:0004672 | non-traceable author statement <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with SGD_LOCUS:YAK1; SGD:S0003677 <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay <newline> beta-catenin binding ; GO:0008013 | inferred from physical interaction with arm <newline> transcription factor binding ; GO:0008134 | inferred from physical interaction with pan <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0037351","Ribosomal protein L13A","RpL13A","The gene Ribosomal protein L13A is referred to in FlyBase by the symbol Dmel\\RpL13A (CG1475, FBgn0037351). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of ribosome. There is experimental evidence that it is involved in the biological process</span>: Notch signaling pathway; bristle morphogenesis. 4 alleles are reported. The phenotype of these alleles is annotated with: macrochaeta. It has one annotated transcript and one annotated polypeptide. Protein features are: Ribosomal protein L13; Ribosomal protein L13, eukaryotic/archaeal. Gene sequence location is 3R:1450186..1451679.","translation ; GO:0006412 | inferred from sequence or structural similarity with SGD_LOCUS:RPL16A; SGD:S0001395 <newline> translation ; GO:0006412 | inferred from sequence or structural similarity with UniProtKB:P41123 <newline> Notch signaling pathway ; GO:0007219 | inferred from genetic interaction with mam inferred from genetic interaction with N <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype","cytosolic large ribosomal subunit ; GO:0022625 | inferred from sequence or structural similarity with SGD_LOCUS:RPL16A; SGD:S0001395 <newline> cytosolic large ribosomal subunit ; GO:0022625 | inferred from sequence or structural similarity with UniProtKB:P41123","structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with SGD_LOCUS:RPL16A; SGD:S0001395 <newline> structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:P41123"]
[]
["Dpp Signaling"]
[null,"FBgn0003396","schnurri","shn","The gene schnurri is referred to in FlyBase by the symbol Dmel\\shn (CG7734, FBgn0003396). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7061325..7104918. It has the cytological map location 47D6-47D7. There is experimental evidence that it has the molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: olfactory learning; ectoderm development; learning or memory; cell proliferation; imaginal disc-derived wing vein morphogenesis; wing disc anterior/posterior pattern formation; wing disc dorsal/ventral pattern formation; imaginal disc-derived wing morphogenesis; midgut development. 108 alleles are reported. The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; peripheral nervous system; adult segment; embryonic nervous system; adult mesothoracic segment; nervous system; external compound sense organ; primordium; embryonic peripheral nervous system; embryonic head; midgut constriction; podocyte; organ system subdivision; multi-cell-component structure; spiracle. It has 4 annotated transcripts and 4 annotated polypeptides.","ectoderm development ; GO:0007398 | inferred from mutant phenotype <newline> midgut development ; GO:0007494 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from mutant phenotype <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from genetic interaction with dpp AND inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> learning or memory ; GO:0007611 | inferred from mutant phenotype <newline> olfactory learning ; GO:0008355 | inferred from mutant phenotype <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement <newline> negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement <newline> compound eye morphogenesis ; GO:0001745 | non-traceable author statement <newline> negative regulation of cell proliferation ; GO:0008285 | non-traceable author statement <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap","nucleus ; GO:0005634 | non-traceable author statement <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:X51435; protein_id:CAA35798.1 <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from mutant phenotype <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003604, InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0003463","short gastrulation","sog","The gene short gastrulation is referred to in FlyBase by the symbol Dmel\\sog (CG9224, FBgn0003463). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15498603..15520573. It has the cytological map location 13E1. It is reported to have molecular function</span>: growth factor activity. There is experimental evidence that it is involved in the biological process</span>: torso signaling pathway; terminal region determination; ring gland development; imaginal disc-derived wing vein morphogenesis; maternal specification of dorsal/ventral axis, oocyte, soma encoded. 104 alleles are reported. The phenotypes of these alleles are annotated with 33 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; embryonic nervous system; peripheral nervous system; primordium; embryonic/larval tracheal system; thoracic segment; embryonic peripheral nervous system; extended germ band embryo. It has one annotated transcript and one annotated polypeptide.","amnioserosa formation ; GO:0007378 | traceable author statement <newline> terminal region determination ; GO:0007362 | inferred from genetic interaction with tor <newline> torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor <newline> ring gland development ; GO:0035271 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> ectoderm development ; GO:0007398 | non-traceable author statement <newline> negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | non-traceable author statement <newline> BMP signaling pathway ; GO:0030509 | non-traceable author statement <newline> zygotic determination of anterior/posterior axis, embryo ; GO:0007354 | non-traceable author statement <newline> regulation of BMP signaling pathway ; GO:0030510 | traceable author statement <newline> ectoderm development ; GO:0007398 | traceable author statement <newline> negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | traceable author statement <newline> positive regulation of transforming growth factor beta receptor signaling pathway ; GO:0030511 | traceable author statement <newline> maternal specification of dorsal/ventral axis, oocyte, soma encoded ; GO:0007313 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | non-traceable author statement","growth factor activity ; GO:0008083 | non-traceable author statement"]
[null,"FBgn0003716","thickveins","tkv","The gene thickveins is referred to in FlyBase by the symbol Dmel\\tkv (CG14026, FBgn0003716). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:5218996..5271353. It has the cytological map location 25D1-25D2. There is experimental evidence that it has the molecular function</span>: transforming growth factor beta receptor activity, type I; specific transcriptional repressor activity; transforming growth factor beta binding. There is experimental evidence for 19 unique biological process</span> terms, many of which group under: anatomical structure development; regulation of biological process; regulation of developmental process; organ development; organ morphogenesis; reproductive process in a multicellular organism; synaptic transmission; regionalization; positive regulation of developmental process; enzyme linked receptor protein signaling pathway. 103 alleles are reported. The phenotypes of these alleles are annotated with 87 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; embryonic/larval tracheal system; primordium; peripheral nervous system; germarium; embryonic nervous system; egg; external compound sense organ; late extended germ band embryo. It has 4 annotated transcripts and 4 annotated polypeptides.","neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype <newline> decapentaplegic receptor signaling pathway ; GO:0008101 | inferred from mutant phenotype inferred from genetic interaction with dpp <newline> dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype inferred from genetic interaction with dpp <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | inferred from genetic interaction with dpp AND inferred from physical interaction with dpp <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from genetic interaction with dpp AND inferred from mutant phenotype <newline> anterior/posterior pattern formation, imaginal disc ; GO:0007448 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | inferred from mutant phenotype <newline> BMP signaling pathway ; GO:0030509 | traceable author statement <newline> germ-line stem cell division ; GO:0042078 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | non-traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> morphogenesis of a branching structure ; GO:0001763 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | non-traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> transforming growth factor beta receptor complex assembly ; GO:0007181 | non-traceable author statement <newline> negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement <newline> compound eye morphogenesis ; GO:0001745 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> genital disc development ; GO:0035215 | inferred from mutant phenotype <newline> regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype <newline> chorion-containing eggshell formation ; GO:0007304 | inferred from genetic interaction with sax <newline> positive regulation of muscle organ development ; GO:0048636 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> regulation of cell-cell adhesion ; GO:0022407 | inferred from mutant phenotype <newline> regulation of cell differentiation ; GO:0045595 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR003605, InterPro:IPR008271, InterPro:IPR017441, InterPro:IPR017442","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with babo <newline> plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> multivesicular body ; GO:0005771 | inferred from direct assay","transforming growth factor beta binding ; GO:0050431 | inferred from physical interaction with dpp <newline> transforming growth factor beta receptor activity, type I ; GO:0005025 | inferred from physical interaction with dpp <newline> transforming growth factor beta receptor activity, type I ; GO:0005025 | inferred from sequence or structural similarity <newline> transforming growth factor beta receptor activity, type I ; GO:0005025 | non-traceable author statement <newline> protein kinase activity ; GO:0004672 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR003605, InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0020245","tout-velu","ttv","The gene tout-velu is referred to in FlyBase by the symbol Dmel\\ttv (CG10117, FBgn0020245). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10414076..10472826. It has the cytological map location 51A7-51B4. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: decapentaplegic receptor signaling pathway; smoothened signaling pathway; glycosaminoglycan biosynthetic process; regulation of smoothened signaling pathway; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; germ cell migration; Wnt receptor signaling pathway; heparin biosynthetic process; heparan sulfate proteoglycan biosynthetic process. 64 alleles are reported. The phenotypes of these alleles are annotated with: dorsal mesothoracic disc; cuticle; macrochaeta; germline cell; denticle belt. It has one annotated transcript and one annotated polypeptide.","germ cell migration ; GO:0008354 | inferred from mutant phenotype <newline> regulation of smoothened signaling pathway ; GO:0008589 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | non-traceable author statement <newline> heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | inferred from genetic interaction with Ext2 <newline> decapentaplegic receptor signaling pathway ; GO:0008101 | inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | traceable author statement <newline> glycosaminoglycan biosynthetic process ; GO:0006024 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | non-traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | non-traceable author statement <newline> Wnt receptor signaling pathway ; GO:0016055 | inferred from mutant phenotype <newline> heparin biosynthetic process ; GO:0030210 | inferred from mutant phenotype <newline> N-acetylglucosamine metabolic process ; GO:0006044 | inferred from sequence or structural similarity with UniProtKB:O77783 <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from direct assay","integral to membrane ; GO:0016021 | non-traceable author statement <newline> Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> intrinsic to endoplasmic reticulum membrane ; GO:0031227 | inferred from electronic annotation with InterPro:IPR015338","acetylglucosaminyltransferase activity ; GO:0008375 | inferred from sequence or structural similarity with EMBL:AF089748 <newline> acetylglucosaminyltransferase activity ; GO:0008375 | non-traceable author statement <newline> glucuronosyltransferase activity ; GO:0015020 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with Ext2 <newline> N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity ; GO:0050509 | inferred from sequence or structural similarity with UniProtKB:O77783 <newline> glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity ; GO:0050508 | inferred from sequence or structural similarity with UniProtKB:O77783"]
[null,"FBgn0024250","brinker","brk","The gene brinker is referred to in FlyBase by the symbol Dmel\\brk (CG9653, FBgn0024250). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7201974..7205165. It has the cytological map location 7B1. There is experimental evidence that it has the molecular function</span>: specific transcriptional repressor activity. There is experimental evidence that it is involved in the biological process</span>: wing disc morphogenesis; cell competition in a multicellular organism; negative regulation of transforming growth factor beta receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; imaginal disc-derived wing morphogenesis. 65 alleles are reported. The phenotypes of these alleles are annotated with 36 unique terms, many of which group under: organ system; primordium; adult segment; embryonic nervous system; adult mesothoracic segment; ventral nerve cord primordium; portion of tissue; somatic stem cell; peripheral nervous system; thoracic segment. It has one annotated transcript and one annotated polypeptide.","negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype <newline> negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | inferred from mutant phenotype <newline> wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | traceable author statement <newline> regulation of BMP signaling pathway ; GO:0030510 | traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | non-traceable author statement <newline> negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | non-traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with dsx <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype"]
[null,"FBgn0041604","dally-like","dlp","The gene dally-like is referred to in FlyBase by the symbol Dmel\\dlp (CG32146, FBgn0041604). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14625720..14664716. It has the cytological map location 70E5-70E7. It is reported to have molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; detection of light stimulus involved in visual perception; axon guidance; compound eye development; imaginal disc-derived wing margin morphogenesis; wing disc dorsal/ventral pattern formation; positive regulation of smoothened signaling pathway; Wnt receptor signaling pathway; regulation of imaginal disc growth; segment polarity determination. 39 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; peripheral nervous system; adult mesothoracic segment; external compound sense organ; organ system; nervous system; cuticle; lamina plexus; dorsal thoracic disc; compound cell cluster organ. It has 2 annotated transcripts and 2 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from genetic interaction with dally AND inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> decapentaplegic receptor signaling pathway ; GO:0008101 | non-traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | traceable author statement <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from expression pattern AND inferred from genetic interaction with wg <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> detection of light stimulus involved in visual perception ; GO:0050908 | inferred from mutant phenotype <newline> positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype <newline> regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype","extracellular region ; GO:0005576 | inferred from sequence or structural similarity <newline> proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR001863 <newline> membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001863","protein binding ; GO:0005515 | non-traceable author statement <newline> heparan sulfate proteoglycan binding ; GO:0043395 | inferred from electronic annotation with InterPro:IPR001863"]
[null,"FBgn0085450","Sno oncogene","Snoo","The gene Sno oncogene is referred to in FlyBase by the symbol Dmel\\Snoo (CG34421, FBgn0085450). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:7892316..7984158. It has the cytological map location 28D3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; nucleotide binding. There is experimental evidence that it is involved in the biological process</span>: neuron development; negative regulation of transforming growth factor beta receptor signaling pathway. 33 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: adult segment; adult mesothoracic segment; multi-cell-component structure; thoracic segment; nervous system; egg; organ system; external compound sense organ; chorion; peripheral nervous system. It has 5 annotated transcripts and 5 annotated polypeptides.","negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | inferred from genetic interaction with babo inferred from genetic interaction with tkv <newline> neuron development ; GO:0048666 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGD:Ski; MGI:MGI:98310","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR014890 <newline> nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR009061"]
[null,"FBgn0259176","bunched","bun","The gene bunched is referred to in FlyBase by the symbol Dmel\\bun (CG42281, FBgn0259176). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12456577..12546630. It has the cytological map location 33E5-33E9. Based on sequence similarity, it is predicted to have molecular function</span>: protein homodimerization activity. There is experimental evidence for 13 unique biological process</span> terms, many of which group under: regulation of biological process; anatomical structure development; reproductive process in a multicellular organism; regulation of developmental process; programmed cell death; ovarian follicle cell development; positive regulation of biological process; positive regulation of cell proliferation; regionalization; regulation of anatomical structure size; gland morphogenesis; regulation of apoptosis; negative regulation of Notch signaling pathway. 140 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: external compound sense organ; peripheral nervous system; adult segment; organ system; nervous system; female germline cyst; egg; chorion; thoracic segment; adult mesothoracic segment. It has 8 annotated transcripts and 8 annotated polypeptides.","decapentaplegic receptor signaling pathway ; GO:0008101 | inferred from genetic interaction with dpp <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype <newline> negative regulation of cell fate specification ; GO:0009996 | inferred from mutant phenotype <newline> ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype <newline> negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype <newline> cell fate determination ; GO:0001709 | non-traceable author statement <newline> dorsal appendage formation ; GO:0046843 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> compound eye development ; GO:0048749 | non-traceable author statement <newline> oogenesis ; GO:0048477 | non-traceable author statement <newline> positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype <newline> positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000580","cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | non-traceable author statement","protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000580"]
[null,"FBgn0259878","Follistatin","Fs","The gene Follistatin is referred to in FlyBase by the symbol Dmel\\Fs (CG33466, FBgn0259878). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11111061..11129084. It has the cytological map location 51E7-51E10. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: negative regulation of decapentaplegic receptor signaling pathway; positive regulation of activin receptor signaling pathway; negative regulation of activin receptor signaling pathway. 6 alleles are reported. The phenotypes of these alleles are annotated with: pupa; air bubble; ISNb; wing; larval optic lobe; anterior pupal spiracle. It has one annotated transcript and one annotated polypeptide.","negative regulation of activin receptor signaling pathway ; GO:0032926 | inferred from direct assay <newline> negative regulation of decapentaplegic receptor signaling pathway ; GO:0090099 | inferred from direct assay <newline> positive regulation of activin receptor signaling pathway ; GO:0032927 | inferred from direct assay","extracellular region ; GO:0005576 | inferred from direct assay","-"]
[]
["EGFR Signaling"]
[null,"FBgn0000472","diminutive","dm","The gene diminutive is referred to in FlyBase by the symbol Dmel\\dm (CG10798, FBgn0000472). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3267216..3280049. It has the cytological map location 3D2. There is experimental evidence that it has the molecular function</span>: transcription factor activity; protein binding; DNA binding. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: regulation of biological process; regulation of metabolic process; multicellular organismal development; regulation of growth; embryonic development; cell proliferation; embryonic development ending in birth or egg hatching; cell cycle; regulation of apoptosis; positive regulation of cellular biosynthetic process; anatomical structure development; cellular process; embryonic pattern specification; negative regulation of Notch signaling pathway. 55 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; peripheral nervous system; nervous system; external compound sense organ; female germline cyst; cell cycle; nucleus; thoracic segment; imaginal precursor; intracellular membrane-bounded organelle. It has one annotated transcript and one annotated polypeptide.","regulation of transcription, DNA-dependent ; GO:0006355 | inferred from direct assay <newline> cell proliferation ; GO:0008283 | inferred from expression pattern <newline> embryonic development ending in birth or egg hatching ; GO:0009792 | inferred from expression pattern <newline> positive regulation of cell growth ; GO:0030307 | traceable author statement <newline> positive regulation of growth ; GO:0045927 | traceable author statement <newline> regulation of cell size ; GO:0008361 | traceable author statement <newline> positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement <newline> DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype <newline> cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype <newline> regulation of organ growth ; GO:0046620 | inferred from mutant phenotype <newline> regulation of cell growth ; GO:0001558 | inferred from mutant phenotype <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | traceable author statement <newline> regulation of cell cycle ; GO:0051726 | traceable author statement <newline> positive regulation of transcription ; GO:0045941 | inferred from mutant phenotype <newline> neurogenesis ; GO:0022008 | inferred from genetic interaction with Egfr <newline> embryonic pattern specification ; GO:0009880 | inferred from genetic interaction with Egfr <newline> negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with N <newline> regulation of apoptosis ; GO:0042981 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:L00039 <newline> protein complex ; GO:0043234 | inferred from physical interaction with gro","DNA binding ; GO:0003677 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:L00039 <newline> protein binding ; GO:0005515 | inferred from physical interaction with lid <newline> protein binding ; GO:0005515 | inferred from physical interaction with gro"]
[null,"FBgn0000547","echinoid","ed","The gene echinoid is referred to in FlyBase by the symbol Dmel\\ed (CG12676, FBgn0000547). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:4031379..4115059. It has the cytological map location 24D4-24D6. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; organ development; cell adhesion; regulation of developmental process; regulation of biological process; cell-cell adhesion; homophilic cell adhesion; regulation of neurogenesis; actin filament-based process; behavioral interaction between organisms; regulation of epidermal growth factor receptor signaling pathway. 60 alleles are reported. The phenotypes of these alleles are annotated with 29 unique terms, many of which group under: peripheral nervous system; external compound sense organ; nervous system; adult segment; adult mesothoracic segment; embryonic nervous system; organ system; histaminergic neuron; embryonic segment; primordium. It has one annotated transcript and one annotated polypeptide.","epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype <newline> cell adhesion ; GO:0007155 | inferred from sequence or structural similarity <newline> negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with Egfr AND inferred from genetic interaction with Gap1 AND inferred from genetic interaction with Ras85D AND inferred from genetic interaction with argos AND inferred from genetic interaction with rho AND inferred from genetic interaction with rl AND inferred from genetic interaction with sty AND inferred from mutant phenotype <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype AND inferred from physical interaction with Nrg <newline> negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> homophilic cell adhesion ; GO:0007156 | inferred from direct assay AND inferred from mutant phenotype <newline> negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype <newline> contractile actin filament bundle assembly ; GO:0030038 | inferred from mutant phenotype <newline> muscle organ morphogenesis ; GO:0048644 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype <newline> mushroom body development ; GO:0016319 | inferred from mutant phenotype","integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> cell-cell adherens junction ; GO:0005913 | inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with Grip"]
[null,"FBgn0003310","Star","S","The gene Star is referred to in FlyBase by the symbol Dmel\\S (CG4385, FBgn0003310). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:1050877..1077811. It has the cytological map location 21E4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: epidermal growth factor ligand processing; stomatogastric nervous system development; determination of genital disc primordium; protein targeting to Golgi; compound eye retinal cell programmed cell death; regulation of epidermal growth factor receptor signaling pathway; ommatidial rotation; imaginal disc-derived wing morphogenesis; behavioral response to ethanol. 151 alleles are reported. The phenotypes of these alleles are annotated with 58 unique terms, many of which group under: organ system; embryonic nervous system; peripheral nervous system; nervous system; adult segment; external compound sense organ; adult mesothoracic segment; embryonic neuron; multi-cell-component structure; female germline cyst; commissure. It has 2 annotated transcripts and 2 annotated polypeptides.","epidermal growth factor ligand processing ; GO:0007174 | inferred from genetic interaction with spi <newline> protein targeting to Golgi ; GO:0000042 | inferred from genetic interaction with spi <newline> regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from genetic interaction with rho, spi <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | traceable author statement <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | non-traceable author statement <newline> compound eye photoreceptor development ; GO:0042051 | non-traceable author statement <newline> protein targeting to Golgi ; GO:0000042 | non-traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> embryonic development ; GO:0009790 | traceable author statement <newline> mesoderm development ; GO:0007498 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> photoreceptor cell development ; GO:0042461 | traceable author statement <newline> regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | traceable author statement <newline> protein targeting to Golgi ; GO:0000042 | traceable author statement <newline> determination of genital disc primordium ; GO:0035225 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | traceable author statement <newline> behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype <newline> stomatogastric nervous system development ; GO:0007421 | inferred from mutant phenotype <newline> compound eye retinal cell programmed cell death ; GO:0046667 | inferred from mutant phenotype <newline> ommatidial rotation ; GO:0016318 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> membrane ; GO:0016020 | non-traceable author statement <newline> Golgi apparatus ; GO:0005794 | non-traceable author statement <newline> endoplasmic reticulum ; GO:0005783 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | traceable author statement","-"]
[null,"FBgn0005672","spitz","spi","The gene spitz is referred to in FlyBase by the symbol Dmel\\spi (CG10334, FBgn0005672). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:19567899..19577324. It has the cytological map location 37F2. It is reported to have molecular function</span>: gurken receptor binding; epidermal growth factor receptor binding. There is experimental evidence that it is involved in the biological process</span>: oenocyte development; border follicle cell migration; stomatogastric nervous system development; spiracle morphogenesis, open tracheal system; negative regulation of apoptosis; determination of genital disc primordium; imaginal disc-derived wing morphogenesis; behavioral response to ethanol; peripheral nervous system development. 80 alleles are reported. The phenotypes of these alleles are annotated with 110 unique terms, many of which group under: peripheral nervous system; nervous system; organ system; external compound sense organ; embryonic nervous system; multi-cell-component structure; hypodermal muscle of larval abdomen; adult segment; cuticle; commissure. It has 7 annotated transcripts and 7 annotated polypeptides.","oenocyte development ; GO:0007438 | inferred from genetic interaction with abd-A AND inferred from mutant phenotype <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | traceable author statement <newline> positive regulation of epidermal growth factor receptor signaling pathway ; GO:0045742 | non-traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | non-traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | non-traceable author statement <newline> G2/M transition of mitotic cell cycle ; GO:0000086 | non-traceable author statement <newline> second mitotic wave during compound eye morphogenesis ; GO:0016330 | non-traceable author statement <newline> R8 cell-mediated photoreceptor organization ; GO:0045470 | non-traceable author statement <newline> anti-apoptosis ; GO:0006916 | non-traceable author statement <newline> negative regulation of compound eye retinal cell programmed cell death ; GO:0046673 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> determination of genital disc primordium ; GO:0035225 | inferred from mutant phenotype <newline> spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype <newline> stomatogastric nervous system development ; GO:0007421 | inferred from mutant phenotype","extracellular region ; GO:0005576 | traceable author statement <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> Golgi apparatus ; GO:0005794 | inferred from genetic interaction with S <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> integral to membrane ; GO:0016021 | non-traceable author statement <newline> endoplasmic reticulum ; GO:0005783 | non-traceable author statement <newline> extracellular region ; GO:0005576 | non-traceable author statement","epidermal growth factor receptor binding ; GO:0005154 | traceable author statement <newline> epidermal growth factor receptor binding ; GO:0005154 | non-traceable author statement <newline> gurken receptor binding ; GO:0008317 | non-traceable author statement"]
[null,"FBgn0015296","SHC-adaptor protein","Shc","The gene SHC-adaptor protein is referred to in FlyBase by the symbol Dmel\\Shc (CG3715, FBgn0015296). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9420100..9421779. It has the cytological map location 67B5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: torso signaling pathway; epidermal growth factor receptor signaling pathway; tracheal outgrowth, open tracheal system. 8 alleles are reported. The phenotypes of these alleles are annotated with: eye; ommatidium. It has one annotated transcript and one annotated polypeptide.","epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from genetic interaction with Egfr <newline> torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor <newline> tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype <newline> intracellular signaling pathway ; GO:0023034 | inferred from electronic annotation with InterPro:IPR006019","-","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000980"]
[null,"FBgn0261885","osa","osa","The gene osa is referred to in FlyBase by the symbol Dmel\\osa (CG7467, FBgn0261885). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:13513540..13544059. It has the cytological map location 90C1-90C2. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; organ development; regulation of biological process; regulation of metabolic process; regionalization; appendage development; positive regulation of cellular biosynthetic process; segment specification; regulation of epidermal growth factor receptor signaling pathway. 62 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: adult segment; adult mesothoracic segment; peripheral nervous system; organ system; nervous system; thoracic segment; dorsal thoracic disc; external compound sense organ; Malpighian tubule; larval thorax; wing cell. It has 4 annotated transcripts and 4 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from mutant phenotype <newline> photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype <newline> segment specification ; GO:0007379 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from direct assay <newline> positive regulation of transcription, DNA-dependent ; GO:0045893 | inferred from direct assay <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> brahma complex ; GO:0035060 | inferred from direct assay <newline> brahma complex ; GO:0035060 | traceable author statement","DNA binding ; GO:0003677 | non-traceable author statement <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> transcription coactivator activity ; GO:0003713 | contributes_to inferred by curator from GO:0035060"]
[null,"FBgn0085403","Rapgap1","Rapgap1","The gene Rapgap1 is referred to in FlyBase by the symbol Dmel\\Rapgap1 (CG34374, FBgn0085403). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: Ras GTPase activator activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: Ras protein signal transduction. 34 alleles are reported. The phenotype of these alleles is annotated with: pigment cell. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: GoLoco motif; Rap/ran-GAP. Gene sequence location is 2L:7497805..7576604.","Ras protein signal transduction ; GO:0007265 | inferred from sequence or structural similarity with HGNC_gene:RAP1GAP; HGNC:9858; OMIM:600278 <newline> regulation of small GTPase mediated signal transduction ; GO:0051056 | inferred from electronic annotation with InterPro:IPR000331","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR000331","Ras GTPase activator activity ; GO:0005099 | inferred from sequence or structural similarity with NCBI_gi:450641"]
[]
["Jnk Signaling"]
[null,"FBgn0001297","kayak","kay","The gene kayak is referred to in FlyBase by the symbol Dmel\\kay (CG33956, FBgn0001297). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25592497..25619838. It has the cytological map location 99B10-99C1. There is experimental evidence that it has the molecular function</span>: protein binding; sequence-specific DNA binding; RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; sensory organ development; response to stress; organ development; organ morphogenesis; cell cycle; cellular component movement; response to external stimulus; regulation of cyclin-dependent protein kinase activity; ovarian follicle cell development; immune response; embryonic development via the syncytial blastoderm; wound healing. 47 alleles are reported. The phenotypes of these alleles are annotated with 44 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; nervous system; embryonic nervous system; external compound sense organ; peripheral nervous system; multi-cell-component structure; imaginal precursor; thoracic segment. It has 4 annotated transcripts and 4 annotated polypeptides.","regulation of cyclin-dependent protein kinase activity during G2/M ; GO:0031660 | inferred from mutant phenotype <newline> second mitotic wave during compound eye morphogenesis ; GO:0016330 | inferred from mutant phenotype <newline> wing disc development ; GO:0035220 | inferred from mutant phenotype <newline> central nervous system development ; GO:0007417 | inferred from mutant phenotype <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> midgut development ; GO:0007494 | inferred from mutant phenotype <newline> JNK cascade ; GO:0007254 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> imaginal disc fusion, thorax closure ; GO:0046529 | traceable author statement <newline> ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype <newline> response to wounding ; GO:0009611 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | non-traceable author statement <newline> R3/R4 cell fate commitment ; GO:0007464 | traceable author statement <newline> establishment of planar polarity ; GO:0001736 | non-traceable author statement <newline> wound healing ; GO:0042060 | inferred from mutant phenotype <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Pvr <newline> R3/R4 cell fate commitment ; GO:0007464 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR004827, InterPro:IPR011616","nucleus ; GO:0005634 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","sequence-specific DNA binding ; GO:0043565 | inferred from direct assay <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | traceable author statement <newline> transcription factor binding ; GO:0008134 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with Cka <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> transcription factor binding ; GO:0008134 | non-traceable author statement <newline> protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity <newline> protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011616 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR004827, InterPro:IPR011616"]
[null,"FBgn0003502","Btk family kinase at 29A","Btk29A","The gene Btk family kinase at 29A is referred to in FlyBase by the symbol Dmel\\Btk29A (CG8049, FBgn0003502). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:8259504..8301072. It has the cytological map location 29A1-29A3. There is experimental evidence that it has the molecular function</span>: protein tyrosine kinase activity. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; ovarian nurse cell to oocyte transport; organelle organization; regulation of cellular component organization; gland morphogenesis; learning; determination of adult lifespan; cell cycle; actin filament-based process; multicellular organism reproduction. 48 alleles are reported. The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; cephalopharyngeal skeleton; female germline cyst; cuticle; integumentary specialisation; region of integument; embryonic foregut; adult; taenidial fold; mouthpart; actin cytoskeleton; egg; spiracle. It has 6 annotated transcripts and 6 annotated polypeptides.","protein amino acid phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with UniProtKB:Q06187 <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype <newline> female germline ring canal formation ; GO:0007301 | inferred from expression pattern <newline> determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> imaginal disc-derived male genitalia development ; GO:0007485 | inferred from direct assay AND inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> cellularization ; GO:0007349 | inferred from mutant phenotype <newline> actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype <newline> karyosome formation ; GO:0030717 | inferred from mutant phenotype <newline> ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype <newline> ovarian fusome organization ; GO:0030723 | inferred from mutant phenotype <newline> DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype <newline> regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> courtship behavior ; GO:0007619 | non-traceable author statement <newline> JNK cascade ; GO:0007254 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> sensitization ; GO:0046960 | inferred from mutant phenotype <newline> intracellular signaling pathway ; GO:0023034 | inferred from electronic annotation with InterPro:IPR001562","cytoplasm ; GO:0005737 | inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> germline ring canal ; GO:0045172 | inferred from direct assay <newline> germline ring canal ; GO:0045172 | traceable author statement","protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity with UniProtKB:Q06187 <newline> protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay <newline> protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement <newline> protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity with UniProtKB:P42680 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR017441 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000980, InterPro:IPR020685"]
[null,"FBgn0020249","steamer duck","stck","The gene steamer duck is referred to in FlyBase by the symbol Dmel\\stck (CG7954, FBgn0020249). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4182689..4185745. It has the cytological map location 84F15. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. There is experimental evidence that it is involved in the biological process</span>: dorsal closure; apposition of dorsal and ventral imaginal disc-derived wing surfaces; embryonic pattern specification; negative regulation of JNK cascade; head involution. 14 alleles are reported. The phenotypes of these alleles are annotated with: larva; embryonic somatic muscle; embryonic/larval somatic muscle. It has 3 annotated transcripts and 3 annotated polypeptides.","apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with msn <newline> embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype <newline> head involution ; GO:0008258 | inferred from mutant phenotype","cell leading edge ; GO:0031252 | inferred from direct assay","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781"]
[null,"FBgn0243512","puckered","puc","The gene puckered is referred to in FlyBase by the symbol Dmel\\puc (CG7850, FBgn0243512). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3931057..3948023. It has the cytological map location 84E12-84E11. There is experimental evidence that it has the molecular function</span>: JUN kinase phosphatase activity; phosphoprotein phosphatase activity. There is experimental evidence for 20 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; organ development; organ morphogenesis; regulation of biological process; actin filament-based process; ovarian follicle cell development; regulation of developmental process; response to stress; organelle organization. 54 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; egg; cuticle; peripheral nervous system; external compound sense organ; adult segment; nervous system; chorion; adult mesothoracic segment; cuticular specialization. It has one annotated transcript and one annotated polypeptide.","imaginal disc eversion ; GO:0007561 | inferred from mutant phenotype <newline> imaginal disc fusion ; GO:0046528 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> epidermis development ; GO:0008544 | inferred from mutant phenotype <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> JNK cascade ; GO:0007254 | non-traceable author statement <newline> suture of dorsal opening ; GO:0007396 | non-traceable author statement <newline> JNK cascade ; GO:0007254 | inferred from mutant phenotype <newline> actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype <newline> protein amino acid dephosphorylation ; GO:0006470 | inferred from direct assay AND inferred from sequence or structural similarity <newline> protein amino acid dephosphorylation ; GO:0006470 | non-traceable author statement <newline> JNK cascade ; GO:0007254 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> wound healing ; GO:0042060 | inferred from expression pattern <newline> negative regulation of JNK cascade ; GO:0046329 | traceable author statement <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> response to oxidative stress ; GO:0006979 | inferred from mutant phenotype <newline> wound healing ; GO:0042060 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> negative regulation of JNK cascade ; GO:0046329 | non-traceable author statement <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> micropyle formation ; GO:0046844 | inferred from mutant phenotype <newline> wound healing ; GO:0042060 | inferred from direct assay <newline> dorsal closure ; GO:0007391 | non-traceable author statement <newline> ommatidial rotation ; GO:0016318 | non-traceable author statement <newline> establishment of planar polarity ; GO:0001736 | non-traceable author statement <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Pvr <newline> regulation of G2/M transition of mitotic cell cycle ; GO:0010389 | inferred from mutant phenotype","Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay","MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | non-traceable author statement <newline> JUN kinase phosphatase activity ; GO:0008579 | inferred from mutant phenotype <newline> phosphoprotein phosphatase activity ; GO:0004721 | inferred from direct assay <newline> protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity <newline> protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from sequence or structural similarity <newline> JUN kinase phosphatase activity ; GO:0008579 | non-traceable author statement <newline> JUN kinase phosphatase activity ; GO:0008579 | traceable author statement <newline> protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement <newline> MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | traceable author statement <newline> protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130"]
[null,"FBgn0038167","lkb1","lkb1","The gene lkb1 is referred to in FlyBase by the symbol Dmel\\lkb1 (CG9374, FBgn0038167). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function</span>: protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: border follicle cell delamination; dorsal closure; regulation of JNK cascade; oocyte microtubule cytoskeleton organization; pole plasm oskar mRNA localization; mitotic spindle organization; asymmetric neuroblast division; positive regulation of apoptosis. 23 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; organelle; adult segment; thoracic segment; spindle; anatomical structure; peripheral nervous system; intracellular organelle part; spindle microtubule; adult. It has 9 annotated transcripts and 9 annotated polypeptides. Protein features are: Calcium/calmodulin-dependent protein kinase-like; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase STK; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain. Gene sequence location is 3R:9502271..9505152.","protein phosphorylation ; GO:0006468 | non-traceable author statement <newline> oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype <newline> establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement <newline> pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype <newline> asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype <newline> border follicle cell delamination ; GO:0030709 | inferred from mutant phenotype <newline> positive regulation of apoptosis ; GO:0043065 | inferred from direct assay <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> regulation of JNK cascade ; GO:0046328 | inferred from direct assay <newline> protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR008271, InterPro:IPR015735, InterPro:IPR017441, InterPro:IPR017442","nucleus ; GO:0005634 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay","protein kinase activity ; GO:0004672 | non-traceable author statement <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR002290, InterPro:IPR008271, InterPro:IPR015735 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR015735, InterPro:IPR017441, InterPro:IPR017442"]
[]
["Hh Signaling"]
[null,"FBgn0004644","hedgehog","hh","The gene hedgehog is referred to in FlyBase by the symbol Dmel\\hh (CG4637, FBgn0004644). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:18953425..18967881. It has the cytological map location 94E1. There is experimental evidence that it has the molecular function</span>: cell surface binding; protein binding. There is experimental evidence for 24 unique biological process</span> terms, many of which group under: anatomical structure development; cellular component movement; organ morphogenesis; regulation of biological process; sensory organ development; reproductive process in a multicellular organism; organ development; regulation of protein transport; cell projection organization; open tracheal system development; central nervous system development. 170 alleles are reported. The phenotypes of these alleles are annotated with 190 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; primordium; nervous system; late extended germ band embryo; ventral nerve cord primordium; embryonic nervous system; abdominal ventral denticle belt. It has 2 annotated transcripts and 2 annotated polypeptides.","pole cell migration ; GO:0007280 | inferred from genetic interaction with Hmgcr inferred from genetic interaction with disp <newline> progression of morphogenetic furrow during compound eye morphogenesis ; GO:0007458 | inferred from expression pattern AND inferred from genetic interaction with dpp AND inferred from genetic interaction with h AND inferred from genetic interaction with sca AND inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo <newline> germ cell migration ; GO:0008354 | inferred from mutant phenotype <newline> gonadal mesoderm development ; GO:0007506 | inferred from mutant phenotype <newline> positive regulation of hh target transcription factor activity ; GO:0007228 | inferred from genetic interaction with Su(fu) AND inferred from genetic interaction with fu <newline> Bolwig's organ morphogenesis ; GO:0001746 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | traceable author statement <newline> hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype <newline> regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype <newline> epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype <newline> glial cell migration ; GO:0008347 | inferred from mutant phenotype <newline> labial disc development ; GO:0035217 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> morphogenesis of larval imaginal disc epithelium ; GO:0016335 | inferred from mutant phenotype <newline> protein autoprocessing ; GO:0016540 | inferred from direct assay AND inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | traceable author statement <newline> positive regulation of smoothened signaling pathway ; GO:0045880 | traceable author statement <newline> protein autoprocessing ; GO:0016540 | traceable author statement <newline> protein splicing ; GO:0030908 | traceable author statement <newline> cytoneme assembly ; GO:0035231 | inferred from mutant phenotype <newline> foregut morphogenesis ; GO:0007440 | traceable author statement <newline> hindgut morphogenesis ; GO:0007442 | traceable author statement <newline> anterior/posterior lineage restriction, imaginal disc ; GO:0048099 | traceable author statement <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | traceable author statement <newline> imaginal disc-derived wing vein specification ; GO:0007474 | traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> ovarian follicle cell stalk formation ; GO:0030713 | traceable author statement <newline> epidermis development ; GO:0008544 | traceable author statement <newline> growth ; GO:0040007 | non-traceable author statement <newline> germ-line stem cell division ; GO:0042078 | traceable author statement <newline> ectoderm development ; GO:0007398 | non-traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> mesoderm development ; GO:0007498 | non-traceable author statement <newline> imaginal disc pattern formation ; GO:0007447 | non-traceable author statement <newline> regulation of organ growth ; GO:0046620 | traceable author statement <newline> analia development ; GO:0007487 | traceable author statement <newline> genital disc development ; GO:0035215 | traceable author statement <newline> leg disc morphogenesis ; GO:0007478 | traceable author statement <newline> regulation of cell proliferation ; GO:0042127 | non-traceable author statement <newline> compartment pattern formation ; GO:0007386 | traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | non-traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | traceable author statement <newline> segment polarity determination ; GO:0007367 | non-traceable author statement <newline> anterior/posterior axis specification, embryo ; GO:0008595 | non-traceable author statement <newline> R8 cell fate specification ; GO:0045464 | non-traceable author statement <newline> heart development ; GO:0007507 | non-traceable author statement <newline> progression of morphogenetic furrow during compound eye morphogenesis ; GO:0007458 | traceable author statement <newline> somatic stem cell division ; GO:0048103 | traceable author statement <newline> protein autoprocessing ; GO:0016540 | non-traceable author statement <newline> wing disc proximal/distal pattern formation ; GO:0007473 | traceable author statement <newline> germ cell attraction ; GO:0035232 | traceable author statement <newline> developmental pigmentation ; GO:0048066 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> regulation of protein import into nucleus ; GO:0042306 | inferred from mutant phenotype <newline> imaginal disc growth ; GO:0007446 | traceable author statement <newline> anterior head segmentation ; GO:0035288 | traceable author statement <newline> posterior head segmentation ; GO:0035289 | traceable author statement <newline> segment polarity determination ; GO:0007367 | traceable author statement <newline> trunk segmentation ; GO:0035290 | traceable author statement <newline> genital disc development ; GO:0035215 | inferred from mutant phenotype <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | traceable author statement <newline> genital disc anterior/posterior pattern formation ; GO:0035224 | inferred from expression pattern <newline> eye morphogenesis ; GO:0048592 | inferred from mutant phenotype <newline> ventral midline development ; GO:0007418 | inferred from mutant phenotype <newline> anterior commissure morphogenesis ; GO:0021960 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from expression pattern <newline> positive regulation of transcription factor import into nucleus ; GO:0042993 | inferred from mutant phenotype <newline> cell-cell signaling ; GO:0007267 | inferred from electronic annotation with InterPro:IPR000320 <newline> proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001767 <newline> intein-mediated protein splicing ; GO:0016539 | inferred from electronic annotation with InterPro:IPR006141","extracellular region ; GO:0005576 | traceable author statement <newline> cytoplasmic membrane-bounded vesicle ; GO:0016023 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | non-traceable author statement <newline> extracellular region ; GO:0005576 | non-traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> endocytic vesicle ; GO:0030139 | inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with iHog <newline> cell surface binding ; GO:0043498 | inferred from direct assay <newline> patched binding ; GO:0005113 | traceable author statement <newline> cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity <newline> signal transducer activity ; GO:0004871 | traceable author statement <newline> morphogen activity ; GO:0016015 | traceable author statement <newline> endopeptidase activity ; GO:0004175 | non-traceable author statement <newline> patched binding ; GO:0005113 | non-traceable author statement <newline> peptidase activity ; GO:0008233 | inferred from electronic annotation with InterPro:IPR001767"]
[null,"FBgn0003371","shaggy","sgg","The gene shaggy is referred to in FlyBase by the symbol Dmel\\sgg (CG2621, FBgn0003371). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2527983..2571879. It has the cytological map location 3A8-3B1. There is experimental evidence that it has the molecular function</span>: protein kinase activity; kinase activity. There is experimental evidence for 16 unique biological process</span> terms, many of which group under: anatomical structure development; regulation of biological process; reproductive process in a multicellular organism; organ development; learning; regulation of circadian rhythm; multicellular organism reproduction; learning or memory; regionalization; biopolymer modification; circadian rhythm; regulation of developmental process; embryonic pattern specification; olfactory learning; entrainment of circadian clock; regulation of metabolic process. 149 alleles are reported. The phenotypes of these alleles are annotated with 44 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; abdominal ventral denticle belt; nervous system; external compound sense organ; cuticle; larval abdominal segment; embryonic/larval hemocoel. It has 15 annotated transcripts and 15 annotated polypeptides.","synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> circadian rhythm ; GO:0007623 | inferred from mutant phenotype <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype <newline> heart development ; GO:0007507 | non-traceable author statement <newline> protein localization ; GO:0008104 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> negative regulation of Wnt receptor signaling pathway ; GO:0030178 | traceable author statement <newline> blastoderm segmentation ; GO:0007350 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> bristle morphogenesis ; GO:0008407 | non-traceable author statement <newline> circadian rhythm ; GO:0007623 | non-traceable author statement <newline> locomotor rhythm ; GO:0045475 | non-traceable author statement <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from direct assay <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay <newline> regulation of proteolysis ; GO:0030162 | inferred from direct assay <newline> circadian rhythm ; GO:0007623 | traceable author statement <newline> Notch signaling pathway ; GO:0007219 | traceable author statement <newline> regulation of protein import into nucleus ; GO:0042306 | traceable author statement <newline> rhythmic behavior ; GO:0007622 | traceable author statement <newline> regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype <newline> entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype <newline> wing and notum subfield formation ; GO:0035309 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> olfactory learning ; GO:0008355 | inferred from mutant phenotype <newline> habituation ; GO:0046959 | inferred from mutant phenotype <newline> regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype","-","protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity <newline> protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement <newline> kinase activity ; GO:0016301 | inferred from direct assay <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> glycogen synthase kinase 3 activity ; GO:0004696 | non-traceable author statement <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017442 <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR002290, InterPro:IPR008271"]
[null,"FBgn0020245","tout-velu","ttv","The gene tout-velu is referred to in FlyBase by the symbol Dmel\\ttv (CG10117, FBgn0020245). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10414076..10472826. It has the cytological map location 51A7-51B4. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: decapentaplegic receptor signaling pathway; smoothened signaling pathway; glycosaminoglycan biosynthetic process; regulation of smoothened signaling pathway; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; germ cell migration; Wnt receptor signaling pathway; heparin biosynthetic process; heparan sulfate proteoglycan biosynthetic process. 64 alleles are reported. The phenotypes of these alleles are annotated with: dorsal mesothoracic disc; cuticle; macrochaeta; germline cell; denticle belt. It has one annotated transcript and one annotated polypeptide.","germ cell migration ; GO:0008354 | inferred from mutant phenotype <newline> regulation of smoothened signaling pathway ; GO:0008589 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | non-traceable author statement <newline> heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | inferred from genetic interaction with Ext2 <newline> decapentaplegic receptor signaling pathway ; GO:0008101 | inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | traceable author statement <newline> glycosaminoglycan biosynthetic process ; GO:0006024 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | non-traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | non-traceable author statement <newline> Wnt receptor signaling pathway ; GO:0016055 | inferred from mutant phenotype <newline> heparin biosynthetic process ; GO:0030210 | inferred from mutant phenotype <newline> N-acetylglucosamine metabolic process ; GO:0006044 | inferred from sequence or structural similarity with UniProtKB:O77783 <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from direct assay","integral to membrane ; GO:0016021 | non-traceable author statement <newline> Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> intrinsic to endoplasmic reticulum membrane ; GO:0031227 | inferred from electronic annotation with InterPro:IPR015338","acetylglucosaminyltransferase activity ; GO:0008375 | inferred from sequence or structural similarity with EMBL:AF089748 <newline> acetylglucosaminyltransferase activity ; GO:0008375 | non-traceable author statement <newline> glucuronosyltransferase activity ; GO:0015020 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with Ext2 <newline> N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity ; GO:0050509 | inferred from sequence or structural similarity with UniProtKB:O77783 <newline> glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity ; GO:0050508 | inferred from sequence or structural similarity with UniProtKB:O77783"]
[null,"FBgn0041604","dally-like","dlp","The gene dally-like is referred to in FlyBase by the symbol Dmel\\dlp (CG32146, FBgn0041604). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14625720..14664716. It has the cytological map location 70E5-70E7. It is reported to have molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; detection of light stimulus involved in visual perception; axon guidance; compound eye development; imaginal disc-derived wing margin morphogenesis; wing disc dorsal/ventral pattern formation; positive regulation of smoothened signaling pathway; Wnt receptor signaling pathway; regulation of imaginal disc growth; segment polarity determination. 39 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; peripheral nervous system; adult mesothoracic segment; external compound sense organ; organ system; nervous system; cuticle; lamina plexus; dorsal thoracic disc; compound cell cluster organ. It has 2 annotated transcripts and 2 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from genetic interaction with dally AND inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> decapentaplegic receptor signaling pathway ; GO:0008101 | non-traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | traceable author statement <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from expression pattern AND inferred from genetic interaction with wg <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> detection of light stimulus involved in visual perception ; GO:0050908 | inferred from mutant phenotype <newline> positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype <newline> regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype","extracellular region ; GO:0005576 | inferred from sequence or structural similarity <newline> proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR001863 <newline> membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001863","protein binding ; GO:0005515 | non-traceable author statement <newline> heparan sulfate proteoglycan binding ; GO:0043395 | inferred from electronic annotation with InterPro:IPR001863"]
[null,"FBgn0000352","costa","cos","The gene costa is referred to in FlyBase by the symbol Dmel\\cos (CG1708, FBgn0000352). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: smoothened binding; microtubule binding; protein binding; protein kinase binding; transcription factor binding. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; regulation of protein stability; negative regulation of transcription factor activity; imaginal disc-derived wing morphogenesis; cytoplasmic sequestering of transcription factor; negative regulation of transcription factor import into nucleus; positive regulation of hh target transcription factor activity. 88 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; thoracic segment; imaginal precursor; adult; dorsal thoracic disc; abdominal segment 10; vulva; epiproct. It has one annotated transcript and one annotated polypeptide. Protein features are: Kinesin, motor domain. Gene sequence location is 2R:3269669..3274617.","ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> positive regulation of hh target transcription factor activity ; GO:0007228 | inferred from mutant phenotype <newline> negative regulation of transcription factor import into nucleus ; GO:0042992 | inferred from mutant phenotype <newline> microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity <newline> regulation of proteolysis ; GO:0030162 | non-traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | inferred from physical interaction with smo <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | traceable author statement <newline> positive regulation of smoothened signaling pathway ; GO:0045880 | traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> regulation of protein stability ; GO:0031647 | inferred from direct assay <newline> negative regulation of transcription factor activity ; GO:0043433 | inferred from mutant phenotype <newline> cytoplasmic sequestering of transcription factor ; GO:0042994 | inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype <newline> microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR001752","cytoplasm ; GO:0005737 | inferred from direct assay <newline> kinesin complex ; GO:0005871 | inferred from sequence or structural similarity with Khc <newline> microtubule associated complex ; GO:0005875 | inferred from physical interaction with ci <newline> kinesin complex ; GO:0005871 | inferred from sequence or structural similarity with SGD_LOCUS:KIP3; SGD:S000003184 <newline> Hedgehog signaling complex ; GO:0035301 | inferred from physical interaction with ci AND inferred from physical interaction with fu <newline> kinesin complex ; GO:0005871 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> vesicle membrane ; GO:0012506 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | traceable author statement","microtubule binding ; GO:0008017 | inferred from direct assay <newline> motor activity ; GO:0003774 | inferred from sequence or structural similarity with Khc <newline> microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity <newline> smoothened binding ; GO:0005119 | inferred from physical interaction with smo <newline> protein binding ; GO:0005515 | inferred from physical interaction with fu <newline> protein kinase binding ; GO:0019901 | inferred from physical interaction with fu <newline> transcription factor binding ; GO:0008134 | inferred from physical interaction with ci <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752 <newline> microtubule motor activity ; GO:0003777 | inferred from electronic annotation with InterPro:IPR001752"]
[]
["JAK-STAT Signaling"]
[null,"FBgn0011236","ken and barbie","ken","The gene ken and barbie is referred to in FlyBase by the symbol Dmel\\ken (CG5575, FBgn0011236). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19757798..19764965. It has the cytological map location 60A6-60A7. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity; protein binding; nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: imaginal disc-derived female genitalia development; female analia development; male analia development; insemination; imaginal disc-derived male genitalia development; regulation of JAK-STAT cascade; phagocytosis, engulfment. 28 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; region of integument; adult; adult segment; antennal segment; embryonic/larval tracheal system; larval abdominal segment; female genitalia; spiracle; vulva; imaginal precursor; integumentary specialisation. It has one annotated transcript and one annotated polypeptide.","copulation ; GO:0007620 | non-traceable author statement <newline> insemination ; GO:0007320 | inferred from mutant phenotype <newline> female analia development ; GO:0045497 | inferred from mutant phenotype <newline> imaginal disc-derived female genitalia development ; GO:0007486 | inferred from mutant phenotype <newline> male analia development ; GO:0045496 | inferred from mutant phenotype <newline> imaginal disc-derived male genitalia development ; GO:0007485 | inferred from mutant phenotype <newline> regulation of JAK-STAT cascade ; GO:0046425 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with InterPro:IPR007087","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity <newline> nucleic acid binding ; GO:0003676 | inferred from sequence or structural similarity with InterPro:IPR007087 <newline> protein binding ; GO:0005515 | inferred from sequence or structural similarity with InterPro:IPR000210 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0036666","tumor suppressor protein 101","TSG101","The gene tumor suppressor protein 101 is referred to in FlyBase by the symbol Dmel\\TSG101 (CG9712, FBgn0036666). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:16835399..16837686. It has the cytological map location 73D1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: negative regulation of growth; negative regulation of growth or development of symbiont in host; regulation of JAK-STAT cascade; negative regulation of imaginal disc growth; maintenance of apical/basal cell polarity. 7 alleles are reported. The phenotypes of these alleles are annotated with: yolk granule; oocyte; vesicle. It has one annotated transcript and one annotated polypeptide.","negative regulation of growth ; GO:0045926 | inferred from mutant phenotype <newline> regulation of JAK-STAT cascade ; GO:0046425 | inferred from mutant phenotype <newline> maintenance of apical/basal cell polarity ; GO:0035090 | inferred from mutant phenotype <newline> negative regulation of imaginal disc growth ; GO:0045571 | inferred from mutant phenotype <newline> negative regulation of growth or development of symbiont in host (obsolete GO:0033667) ; GO:0033667 | inferred from mutant phenotype <newline> regulation of protein metabolic process ; GO:0051246 | inferred from electronic annotation with InterPro:IPR000608 <newline> post-translational protein modification ; GO:0043687 | inferred from electronic annotation with InterPro:IPR000608 <newline> protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR008883","-","protein binding ; GO:0005515 | inferred from physical interaction with Vps28 <newline> small conjugating protein ligase activity ; GO:0019787 | inferred from electronic annotation with InterPro:IPR000608"]
[null,"FBgn0053542","unpaired 3","upd3","The gene unpaired 3 is referred to in FlyBase by the symbol Dmel\\upd3 (CG33542, FBgn0053542). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:18171266..18178632. It has the cytological map location 17A4. Based on sequence similarity, it is predicted to have molecular function</span>: receptor binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: JAK-STAT cascade. 10 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: embryonic segment; embryonic abdomen; embryonic tagma; thoracic segment; embryonic thoracic segment; anatomical structure; abdominal segment 7; embryonic abdominal segment 4; spiracle; embryonic thorax. It has one annotated transcript and one annotated polypeptide.","JAK-STAT cascade ; GO:0007259 | inferred from sequence or structural similarity with os <newline> immune response ; GO:0006955 | non-traceable author statement <newline> JAK-STAT cascade ; GO:0007259 | traceable author statement <newline> antimicrobial humoral response ; GO:0019730 | traceable author statement","extracellular region ; GO:0005576 | inferred from sequence or structural similarity with os <newline> extracellular region ; GO:0005576 | traceable author statement","receptor binding ; GO:0005102 | inferred from sequence or structural similarity with os <newline> cytokine activity ; GO:0005125 | non-traceable author statement <newline> cytokine activity ; GO:0005125 | traceable author statement"]
[null,"FBgn0043903","domeless","dome","The gene domeless is referred to in FlyBase by the symbol Dmel\\dome (CG14226, FBgn0043903). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: transmembrane receptor activity. There is experimental evidence that it is involved in the biological process</span>: blastoderm segmentation; morphogenesis of an epithelium; hindgut morphogenesis; border follicle cell migration; JAK-STAT cascade; open tracheal system development; compound eye morphogenesis. 45 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; anatomical structure; integumentary specialisation; spiracle; multi-tissue structure; region of integument; ovariole; portion of tissue; embryonic hindgut; non-connected developing functional system; external compound sense organ; adult segment. It has one annotated transcript and one annotated polypeptide. Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin-like fold. Gene sequence location is X:19570090..19577549.","JAK-STAT cascade ; GO:0007259 | non-traceable author statement <newline> JAK-STAT cascade ; GO:0007259 | inferred from genetic interaction with Stat92E AND inferred from genetic interaction with os <newline> blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> JAK-STAT cascade ; GO:0007259 | inferred from genetic interaction with hop AND inferred from genetic interaction with os <newline> morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> protein dephosphorylation ; GO:0006470 | non-traceable author statement <newline> blastoderm segmentation ; GO:0007350 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | non-traceable author statement <newline> JAK-STAT cascade ; GO:0007259 | traceable author statement <newline> hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype <newline> epithelial cell fate determination, open tracheal system ; GO:0007425 | traceable author statement <newline> immune response ; GO:0006955 | traceable author statement <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC_gene:CNTFR; HGNC:2170; OMIM:118946 AND inferred from sequence or structural similarity with HGNC_gene:LIFR; HGNC:6597; OMIM:151443 <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> apicolateral plasma membrane ; GO:0016327 | inferred from direct assay <newline> apical plasma membrane ; GO:0016324 | traceable author statement","transmembrane receptor activity ; GO:0004888 | inferred from genetic interaction with os AND inferred from sequence or structural similarity with HGNC_gene:CNTFR; HGNC:2170; OMIM:118946 AND inferred from sequence or structural similarity with HGNC_gene:LIFR; HGNC:6597; OMIM:151443 AND inferred from sequence or structural similarity with MGD:Cntfr; MGI:MGI:99605 AND inferred from sequence or structural similarity with MGD:Lifr; MGI:MGI:96788 <newline> protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement <newline> transmembrane receptor activity ; GO:0004888 | traceable author statement <newline> cytokine binding ; GO:0019955 | non-traceable author statement"]
[]
["Toll Signaling"]
[null,"FBgn0025574","Pellino","Pli","The gene Pellino is referred to in FlyBase by the symbol Dmel\\Pli (CG5212, FBgn0025574). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19685884..19715797. It has the cytological map location 95C5-95C8. There is experimental evidence that it has the molecular function</span>: kinase regulator activity. There is experimental evidence that it is involved in the biological process</span>: Toll signaling pathway. 15 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","Toll signaling pathway ; GO:0008063 | inferred from mutant phenotype <newline> defense response ; GO:0006952 | non-traceable author statement <newline> signal transduction ; GO:0007165 | non-traceable author statement <newline> immune response ; GO:0006955 | traceable author statement <newline> Toll signaling pathway ; GO:0008063 | traceable author statement","cellular_component ; GO:0005575 | no biological data available","kinase regulator activity ; GO:0019207 | inferred from mutant phenotype"]
[]
["Hippo Signaling"]
[null,"FBgn0262127","kibra ortholog","kibra","The gene kibra ortholog is referred to in FlyBase by the symbol Dmel\\kibra (CG33967, FBgn0262127). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: regulation of hippo signaling pathway; compound eye morphogenesis. 46 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; eye. It has one annotated transcript and one annotated polypeptide. Protein features are: C2 calcium-dependent membrane targeting; C2 calcium/lipid-binding domain, CaLB; WW/Rsp5/WWP. Gene sequence location is 3R:10524252..10549978.","regulation of hippo signaling cascade ; GO:0035330 | inferred from genetic interaction with hpo inferred from genetic interaction with Mer inferred from genetic interaction with ex <newline> regulation of hippo signaling cascade ; GO:0035330 | inferred from genetic interaction with hpo inferred from genetic interaction with yki <newline> regulation of hippo signaling cascade ; GO:0035330 | inferred from genetic interaction with ex inferred from genetic interaction with Mer inferred from genetic interaction with sav inferred from genetic interaction with hpo <newline> compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with crb","apical part of cell ; GO:0045177 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with Mer inferred from physical interaction with ex inferred from physical interaction with wts <newline> protein binding ; GO:0005515 | inferred from physical interaction with Mer <newline> protein binding ; GO:0005515 | inferred from physical interaction with sav"]
[]
["Transcription factors Upstream of Hox genes"]
[null,"FBgn0003862","trithorax","trx","The gene trithorax is referred to in FlyBase by the symbol Dmel\\trx (CG8651, FBgn0003862). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:10089080..10112623. It has the cytological map location 88B1. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding. There is experimental evidence that it is involved in the biological process</span>: histone methylation; axon guidance; histone H3-K4 methylation; germ cell migration. 135 alleles are reported. The phenotypes of these alleles are annotated with 38 unique terms, many of which group under: adult segment; organ system; peripheral nervous system; nervous system; adult; midgut constriction; antennal segment; integumentary plate; thoracic segment; appendage segment. It has 5 annotated transcripts and 5 annotated polypeptides.","germ cell migration ; GO:0008354 | inferred from mutant phenotype <newline> germ cell migration ; GO:0008354 | traceable author statement <newline> chromatin-mediated maintenance of transcription ; GO:0048096 | non-traceable author statement <newline> histone methylation ; GO:0016571 | inferred from direct assay <newline> histone methylation ; GO:0016571 | traceable author statement <newline> histone H3-K4 methylation ; GO:0051568 | inferred from direct assay <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR016569","nucleus ; GO:0005634 | non-traceable author statement <newline> histone methyltransferase complex ; GO:0035097 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","DNA binding ; GO:0003677 | non-traceable author statement <newline> histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR001841, InterPro:IPR001965 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR001841, InterPro:IPR001965, InterPro:IPR011011, InterPro:IPR016569 <newline> histone methyltransferase activity (H3-K4 specific) ; GO:0042800 | inferred from electronic annotation with InterPro:IPR016569 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001628"]
[null,"FBgn0004399","pipsqueak","psq","The gene pipsqueak is referred to in FlyBase by the symbol Dmel\\psq (CG2368, FBgn0004399). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6445409..6503753. It has the cytological map location 47A13-47B1. It is reported to have molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: olfactory behavior; imaginal disc-derived wing morphogenesis. 79 alleles are reported. The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: embryonic abdomen; embryonic segment; organ system; embryonic tagma; peripheral nervous system; female germline cyst; external compound sense organ; adult segment; nervous system; adult mesothoracic segment. It has 12 annotated transcripts and 12 annotated polypeptides.","pole plasm assembly ; GO:0007315 | non-traceable author statement <newline> gene silencing ; GO:0016458 | traceable author statement <newline> olfactory behavior ; GO:0042048 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype","nucleus ; GO:0005634 | traceable author statement","DNA binding ; GO:0003677 | non-traceable author statement <newline> DNA binding ; GO:0003677 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR011526 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000210, InterPro:IPR011333, InterPro:IPR013069"]
[null,"FBgn0004861","polyhomeotic proximal","ph-p","The gene polyhomeotic proximal is referred to in FlyBase by the symbol Dmel\\ph-p (CG18412, FBgn0004861). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2020243..2030888. It has the cytological map location 2D2-2D3. There is experimental evidence that it has the molecular function</span>: chaperone binding; protein binding; chromatin binding. There is experimental evidence that it is involved in the biological process</span>: central nervous system neuron development; gene silencing; germarium-derived female germ-line cyst encapsulation; ovarian follicle cell stalk formation; response to ecdysone; syncytial blastoderm mitotic cell cycle. 44 alleles are reported. The phenotypes of these alleles are annotated with 20 unique terms, many of which group under: adult segment; organ system; germarium; female germline cyst; peripheral nervous system; metatarsus; adult mesothoracic segment; nervous system; germarium region 3; adult external prothorax; larval abdominal segment; external compound sense organ. It has 2 annotated transcripts and 2 annotated polypeptides.","gene silencing ; GO:0016458 | inferred from genetic interaction with Pc AND inferred from genetic interaction with Scm AND inferred from genetic interaction with esc <newline> germarium-derived female germ-line cyst encapsulation ; GO:0030708 | inferred from mutant phenotype <newline> ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype <newline> chromatin silencing ; GO:0006342 | non-traceable author statement <newline> syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype <newline> response to ecdysone ; GO:0035075 | inferred from mutant phenotype <newline> central nervous system neuron development ; GO:0021954 | inferred from mutant phenotype","nucleus ; GO:0005634 | non-traceable author statement <newline> PRC1 complex ; GO:0035102 | traceable author statement <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> nucleolus ; GO:0005730 | inferred from direct assay","DNA binding ; GO:0003677 | non-traceable author statement <newline> chromatin binding ; GO:0003682 | inferred from direct assay <newline> chaperone binding ; GO:0051087 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P41046 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR012313"]
[null,"FBgn0005630","longitudinals lacking","lola","The gene longitudinals lacking is referred to in FlyBase by the symbol Dmel\\lola (CG12052, FBgn0005630). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6369712..6430767. It has the cytological map location 47A11-47A13. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence for 12 unique biological process</span> terms, many of which group under: anatomical structure development; cell projection organization; cellular component movement; behavior; sensory organ development; organ morphogenesis; immune response; programmed cell death; neuromuscular process; behavioral interaction between organisms; locomotory behavior; regulation of metabolic process. 163 alleles are reported. The phenotypes of these alleles are annotated with 40 unique terms, many of which group under: peripheral nervous system; nervous system; abdominal lateral monoscolopidial chordotonal organ lch1; embryonic neuron; embryonic nervous system; organ system; multi-cell-component structure; adult segment; abdominal longitudinal muscle; ventral longitudinal muscle. It has 26 annotated transcripts and 26 annotated polypeptides.","axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> axonogenesis ; GO:0007409 | inferred from mutant phenotype <newline> positive regulation of transcription, DNA-dependent ; GO:0045893 | inferred from sequence or structural similarity with UniProtKB:Q08605 <newline> axon midline choice point recognition ; GO:0016199 | inferred from genetic interaction with robo AND inferred from genetic interaction with sli AND inferred from mutant phenotype <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> axon guidance ; GO:0007411 | non-traceable author statement <newline> axon guidance ; GO:0007411 | inferred from genetic interaction with SoxN <newline> brain morphogenesis ; GO:0048854 | inferred from mutant phenotype <newline> startle response ; GO:0001964 | inferred from mutant phenotype <newline> locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype <newline> nurse cell apoptosis ; GO:0045476 | inferred from mutant phenotype <newline> R7 cell development ; GO:0045467 | inferred from mutant phenotype <newline> R3/R4 cell fate commitment ; GO:0007464 | inferred from mutant phenotype <newline> regulation of gene-specific transcription ; GO:0032583 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from sequence or structural similarity with ttk AND inferred from sequence or structural similarity with HGNC_gene:ZBTB25; HGNC:13112; OMIM:194541 <newline> transcription activator activity ; GO:0016563 | inferred from sequence or structural similarity with UniProtKB:Q08605 <newline> protein binding ; GO:0005515 | inferred from physical interaction with JIL-1 <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0001235","homothorax","hth","The gene homothorax is referred to in FlyBase by the symbol Dmel\\hth (CG17117, FBgn0001235). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:6335569..6464386. It has the cytological map location 86C1-86C3. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of gene-specific transcription from RNA polymerase II promoter; compound eye development; specification of segmental identity, antennal segment; specification of segmental identity, head; segmentation; compound eye photoreceptor fate commitment; brain development; imaginal disc-derived wing morphogenesis; haltere morphogenesis; imaginal disc-derived leg morphogenesis. 64 alleles are reported. The phenotypes of these alleles are annotated with 63 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; thoracic segment; external compound sense organ; appendage segment; adult mesothoracic segment; embryonic segment; embryonic nervous system; organ system; antennal segment. It has 8 annotated transcripts and 8 annotated polypeptides.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> brain development ; GO:0007420 | inferred from mutant phenotype <newline> proximal/distal pattern formation ; GO:0009954 | traceable author statement <newline> specification of organ identity ; GO:0010092 | traceable author statement <newline> compound eye photoreceptor fate commitment ; GO:0001752 | inferred from mutant phenotype <newline> leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype <newline> specification of segmental identity, antennal segment ; GO:0007383 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype <newline> haltere morphogenesis ; GO:0048735 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> transcription factor activity ; GO:0003700 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356"]
[null,"FBgn0013263","Trithorax-like","Trl","The gene Trithorax-like is referred to in FlyBase by the symbol Dmel\\Trl (CG33261, FBgn0013263). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14741029..14754149. It has the cytological map location 70F4. There is experimental evidence that it has the molecular function</span>: protein binding; specific RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: cellular process; dosage compensation; nuclear division; syncytial blastoderm mitotic cell cycle; imaginal disc-derived wing morphogenesis; protein oligomerization. 68 alleles are reported. The phenotypes of these alleles are annotated with: eye; abdominal segment 6; egg; sex comb; micropyle; wing; imaginal disc; egg chamber; chromatin; denticle belt. It has 9 annotated transcripts and 9 annotated polypeptides.","nuclear division ; GO:0000280 | inferred from mutant phenotype <newline> syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | non-traceable author statement <newline> chromatin organization ; GO:0006325 | non-traceable author statement <newline> dosage compensation ; GO:0007549 | inferred from mutant phenotype <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> positive regulation of transcription, DNA-dependent ; GO:0045893 | traceable author statement <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> protein oligomerization ; GO:0051259 | inferred from direct assay","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> centromeric heterochromatin ; GO:0005721 | inferred from direct assay AND traceable author statement <newline> chromatin ; GO:0000785 | non-traceable author statement","DNA binding ; GO:0003677 | non-traceable author statement <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from mutant phenotype <newline> protein binding ; GO:0005515 | inferred from physical interaction with Ssrp <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P17789 <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P41046 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0259240","Tenascin accessory","Ten-a","The gene Tenascin accessory is referred to in FlyBase by the symbol Dmel\\Ten-a (CG42338, FBgn0259240). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:12087914..12226216. It has the cytological map location 11A6-11A8. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: periodic partitioning by pair rule gene. 27 alleles are reported. The phenotypes of these alleles are annotated with: interommatidial bristle; ommatidium. It has 7 annotated transcripts and 7 annotated polypeptides.","cell adhesion ; GO:0007155 | inferred from sequence or structural similarity with MGD:Tnc; MGI:MGI:101922 <newline> cell-matrix adhesion ; GO:0007160 | inferred from sequence or structural similarity with EMBL:AB025413; protein_id:BAA77399.1 AND inferred from sequence or structural similarity with EMBL:AF059485 <newline> periodic partitioning by pair rule gene ; GO:0007366 | inferred from mutant phenotype","proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> extracellular region ; GO:0005576 | inferred from sequence or structural similarity with MGD:Tnc; MGI:MGI:101922","-"]
[null,"FBgn0261885","osa","osa","The gene osa is referred to in FlyBase by the symbol Dmel\\osa (CG7467, FBgn0261885). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:13513540..13544059. It has the cytological map location 90C1-90C2. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; organ development; regulation of biological process; regulation of metabolic process; regionalization; appendage development; positive regulation of cellular biosynthetic process; segment specification; regulation of epidermal growth factor receptor signaling pathway. 62 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: adult segment; adult mesothoracic segment; peripheral nervous system; organ system; nervous system; thoracic segment; dorsal thoracic disc; external compound sense organ; Malpighian tubule; larval thorax; wing cell. It has 4 annotated transcripts and 4 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from mutant phenotype <newline> photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype <newline> segment specification ; GO:0007379 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from direct assay <newline> positive regulation of transcription, DNA-dependent ; GO:0045893 | inferred from direct assay <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> brahma complex ; GO:0035060 | inferred from direct assay <newline> brahma complex ; GO:0035060 | traceable author statement","DNA binding ; GO:0003677 | non-traceable author statement <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> transcription coactivator activity ; GO:0003713 | contributes_to inferred by curator from GO:0035060"]
[]
["Hox genes"]
[null,"FBgn0000439","Deformed","Dfd","The gene Deformed is referred to in FlyBase by the symbol Dmel\\Dfd (CG2189, FBgn0000439). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2617558..2628153. It has the cytological map location 84A5. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding. There is experimental evidence that it is involved in the biological process</span>: embryonic morphogenesis; embryonic development; brain development; induction of apoptosis. 43 alleles are reported. The phenotypes of these alleles are annotated with 36 unique terms, many of which group under: embryonic segment; organ system; nervous system; peripheral nervous system; thoracic segment; cephalopharyngeal skeleton; external compound sense organ; cuticle; multi-cell-component structure; adult brain; antennal segment; mouthpart. It has one annotated transcript and one annotated polypeptide.","brain development ; GO:0007420 | inferred from mutant phenotype <newline> embryonic development ; GO:0009790 | inferred from mutant phenotype <newline> embryonic morphogenesis ; GO:0048598 | inferred from mutant phenotype <newline> induction of apoptosis ; GO:0006917 | inferred from genetic interaction with th AND inferred from mutant phenotype <newline> specification of segmental identity, head ; GO:0007380 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR001827, InterPro:IPR017970, InterPro:IPR017995","nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR017970, InterPro:IPR017995","RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> transcription factor activity ; GO:0003700 | traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR001827, InterPro:IPR017995"]
[null,"FBgn0003339","Sex combs reduced","Scr","The gene Sex combs reduced is referred to in FlyBase by the symbol Dmel\\Scr (CG1030, FBgn0003339). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2648842..2675886. It has the cytological map location 84A5. Based on sequence similarity, it is predicted to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: sex comb development. 99 alleles are reported. The phenotypes of these alleles are annotated with 44 unique terms, many of which group under: adult segment; embryonic segment; peripheral nervous system; thoracic segment; embryonic abdomen; mouthpart; appendage segment; nervous system; adult mesothoracic segment; external compound sense organ; antennal segment. It has 3 annotated transcripts and 3 annotated polypeptides.","segment specification ; GO:0007379 | non-traceable author statement <newline> sex comb development ; GO:0045498 | non-traceable author statement <newline> specification of segmental identity, labial segment ; GO:0007381 | traceable author statement <newline> sex comb development ; GO:0045498 | inferred from mutant phenotype <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with UniProtKB:P10628 <newline> midgut development ; GO:0007494 | traceable author statement <newline> sex differentiation ; GO:0007548 | traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | non-traceable author statement","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P10628 <newline> nucleus ; GO:0005634 | non-traceable author statement","specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from sequence or structural similarity with UniProtKB:P10628 <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR001827, InterPro:IPR017995"]
[null,"FBgn0260642","Antennapedia","Antp","The gene Antennapedia is referred to in FlyBase by the symbol Dmel\\Antp (CG1028, FBgn0260642). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2721975..2824950. It has the cytological map location 84A6-84B2. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: heart development; specification of segmental identity, antennal segment; lymph gland development. 148 alleles are reported. The phenotypes of these alleles are annotated with 61 unique terms, many of which group under: adult segment; peripheral nervous system; adult external prothorax; adult mesothoracic segment; antennal segment; organ system; nervous system; humeral trabecule; primordium; imaginal precursor. It has 11 annotated transcripts and 11 annotated polypeptides.","specification of segmental identity, antennal segment ; GO:0007383 | inferred from mutant phenotype <newline> midgut development ; GO:0007494 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> segment specification ; GO:0007379 | non-traceable author statement <newline> heart development ; GO:0007507 | inferred from expression pattern <newline> lymph gland development ; GO:0048542 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR001827, InterPro:IPR017970, InterPro:IPR017995","nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR017970, InterPro:IPR017995","specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR001827, InterPro:IPR017995"]
[]
["Chromatin modulators"]
[null,"FBgn0010313","corto","corto","The gene corto is referred to in FlyBase by the symbol Dmel\\corto (CG2530, FBgn0010313). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:909343..912408. It has the cytological map location 82E7. There is experimental evidence that it has the molecular function</span>: protein binding; identical protein binding; protein homodimerization activity. It is reported to be involved in the biological process</span>: chromatin silencing. 25 alleles are reported. The phenotypes of these alleles are annotated with 24 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; nervous system; adult external prothorax; embryonic/larval hemocoel; metatarsus; hemocyte; cell part; podocyte; endocrine system; imaginal precursor; external compound sense organ; antennal segment. It has one annotated transcript and one annotated polypeptide.","chromatin silencing ; GO:0006342 | inferred by curator from GO:0035102 inferred by curator from GO:0035098","centrosome ; GO:0005813 | non-traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> polytene chromosome ; GO:0005700 | inferred from direct assay <newline> ESC/E(Z) complex ; GO:0035098 | inferred from physical interaction with UniProtKB:Q24338 inferred from physical interaction with UniProtKB:P42124 <newline> PRC1 complex ; GO:0035102 | inferred from physical interaction with UniProtKB:Q9VHA0 inferred from physical interaction with UniProtKB:P39769","RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> protein binding ; GO:0005515 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P39769 inferred from physical interaction with UniProtKB:P42124 inferred from physical interaction with UniProtKB:Q08605 inferred from physical interaction with UniProtKB:Q24338 inferred from physical interaction with UniProtKB:Q9VHA0 <newline> identical protein binding ; GO:0042802 | inferred from physical interaction with UniProtKB:P41046 <newline> protein homodimerization activity ; GO:0042803 | inferred from physical interaction with UniProtKB:P41046"]
[null,"FBgn0026143","CDC45L","CDC45L","The gene CDC45L is referred to in FlyBase by the symbol Dmel\\CDC45L (CG3658, FBgn0026143). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:922324..924606. It has the cytological map location 1E1. There is experimental evidence that it has the molecular function</span>: 3'-5' DNA helicase activity; chromatin binding. There is experimental evidence that it is involved in the biological process</span>: DNA amplification; DNA replication; positive regulation of S phase of mitotic cell cycle; chromosome condensation. 4 alleles are reported. The phenotype of these alleles is annotated with: nuclear chromosome. It has one annotated transcript and one annotated polypeptide.","DNA amplification ; GO:0006277 | inferred from expression pattern <newline> DNA replication ; GO:0006260 | inferred from physical interaction with Mcm5 AND inferred from physical interaction with dpa <newline> DNA replication initiation ; GO:0006270 | inferred from sequence or structural similarity with HGNC_gene:CDC45L; HGNC:1739; OMIM:603465 AND inferred from sequence or structural similarity with SGD_LOCUS:CDC45; SGD:S0004093 <newline> chromosome condensation ; GO:0030261 | inferred from mutant phenotype <newline> DNA replication ; GO:0006260 | inferred from sequence or structural similarity with EMBL:AF062494 <newline> positive regulation of S phase of mitotic cell cycle ; GO:0045750 | inferred from mutant phenotype <newline> DNA replication initiation ; GO:0006270 | inferred from electronic annotation with InterPro:IPR003874","cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> pre-replicative complex ; GO:0005656 | inferred from physical interaction with Mcm5 AND inferred from physical interaction with dpa AND inferred from sequence or structural similarity with HGNC_gene:CDC45L; HGNC:1739; OMIM:603465 AND inferred from sequence or structural similarity with SGD_LOCUS:CDC45; SGD:S0004093 <newline> pre-replicative complex ; GO:0005656 | inferred from sequence or structural similarity with EMBL:AF062494","chromatin binding ; GO:0003682 | inferred from direct assay <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity with EMBL:AF062494 <newline> 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay"]
[null,"FBgn0026160","tonalli","tna","The gene tonalli is referred to in FlyBase by the symbol Dmel\\tna (CG7958, FBgn0026160). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:10828628..10867746. It has the cytological map location 67F1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. There is experimental evidence that it is involved in the biological process</span>: chromatin-mediated maintenance of transcription. 15 alleles are reported. The phenotypes of these alleles are annotated with: haltere; sex comb; wing. It has 4 annotated transcripts and 4 annotated polypeptides.","chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from genetic interaction with Antp AND inferred from genetic interaction with Pc AND inferred from genetic interaction with Scr AND inferred from genetic interaction with brm AND inferred from genetic interaction with kis AND inferred from genetic interaction with osa","-","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR004181"]
[null,"FBgn0031876","ATAC component 1","Atac1","The gene ATAC component 1 is referred to in FlyBase by the symbol Dmel\\Atac1 (CG9200, FBgn0031876). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:6959099..6960285. It has the cytological map location 27C7. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: regulation of histone acetylation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","regulation of histone acetylation ; GO:0035065 | inferred from direct assay","H4/H2A histone acetyltransferase complex ; GO:0043189 | inferred from direct assay","DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001005"]
[null,"FBgn0037770","Arginine methyltransferase 4","Art4","The gene Arginine methyltransferase 4 is referred to in FlyBase by the symbol Dmel\\Art4 (CG5358, FBgn0037770). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5808908..5811777. It has the cytological map location 85F4. There is experimental evidence that it has the molecular function</span>: protein-arginine omega-N asymmetric methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; histone methyltransferase activity. There is experimental evidence that it is involved in the biological process</span>: histone methylation; induction of programmed cell death by ecdysone; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine. 9 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","histone methylation ; GO:0016571 | inferred from direct assay <newline> induction of programmed cell death by ecdysone ; GO:0035078 | inferred from mutant phenotype <newline> peptidyl-arginine methylation, to asymmetrical-dimethyl arginine ; GO:0019919 | inferred from direct assay","histone methyltransferase complex ; GO:0035097 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay","histone methyltransferase activity ; GO:0042054 | inferred from direct assay <newline> histone-arginine N-methyltransferase activity ; GO:0008469 | inferred from sequence or structural similarity with MGD:Carm1; MGI:MGI:1913208 <newline> protein-arginine omega-N asymmetric methyltransferase activity ; GO:0035242 | inferred from direct assay <newline> protein-arginine omega-N monomethyltransferase activity ; GO:0035241 | inferred from direct assay <newline> protein-arginine N-methyltransferase activity ; GO:0016274 | inferred from sequence or structural similarity with UniProtKB:Q63009"]
[null,"FBgn0040071","taranis","tara","The gene taranis is referred to in FlyBase by the symbol Dmel\\tara (CG6889, FBgn0040071). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12051371..12086024. It has the cytological map location 89B8-89B9. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: wing disc dorsal/ventral pattern formation; chromatin-mediated maintenance of transcription. 93 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; trichogen cell; macrochaeta; haltere; tormogen cell; scutellar bristle; wing; arista. It has 2 annotated transcripts and 2 annotated polypeptides.","chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from genetic interaction with Pc AND inferred from genetic interaction with brm AND inferred from genetic interaction with osa AND inferred from genetic interaction with pb AND inferred from genetic interaction with ph-p AND inferred from genetic interaction with trx <newline> chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from genetic interaction with brm AND inferred from genetic interaction with osa AND inferred from genetic interaction with tna <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap","-","-"]
[null,"FBgn0086899","Tousled-like kinase","tlk","The gene Tousled-like kinase is referred to in FlyBase by the symbol Dmel\\tlk (CG34412, FBgn0086899). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3614054..3682010. It has the cytological map location 3F1-3E7. There is experimental evidence that it has the molecular function</span>: protein binding; protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; protein amino acid autophosphorylation; mitotic cell cycle, embryonic; chromatin organization; chromosome segregation; protein amino acid phosphorylation; cell adhesion; histone phosphorylation; antimicrobial humoral response; regulation of cell cycle. 83 alleles are reported. The phenotypes of these alleles are annotated with: larval salivary gland; eye; macrochaeta; head. It has 8 annotated transcripts and 8 annotated polypeptides.","protein amino acid phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with EMBL:AF045253 <newline> cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> chromatin organization ; GO:0006325 | inferred from genetic interaction with asf1 <newline> histone phosphorylation ; GO:0016572 | inferred from mutant phenotype <newline> mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype <newline> protein amino acid autophosphorylation ; GO:0046777 | inferred from direct assay <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype <newline> chromosome segregation ; GO:0007059 | inferred from genetic interaction with mars","nucleus ; GO:0005634 | inferred from direct assay","protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with EMBL:AF045253 <newline> protein kinase activity ; GO:0004672 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with asf1 <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC_gene:TLK1; HGNC:11841; OMIM:608438 AND inferred from sequence or structural similarity with HGNC_gene:TLK2; HGNC:11842; OMIM:608439 AND inferred from sequence or structural similarity with TAIR:gene:1944622 <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with EMBL:AF045252; protein_id:AAC02225.1 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0086902","kismet","kis","The gene kismet is referred to in FlyBase by the symbol Dmel\\kis (CG3696, FBgn0086902). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:210732..250795. It has the cytological map location 21B4-21B5. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent helicase activity. There is experimental evidence that it is involved in the biological process</span>: blastoderm segmentation; segment specification; border follicle cell migration; axon guidance; antimicrobial humoral response. 128 alleles are reported. The phenotypes of these alleles are annotated with: leg; imaginal disc. It has 3 annotated transcripts and 3 annotated polypeptides.","blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype <newline> segment specification ; GO:0007379 | inferred from mutant phenotype <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> chromatin assembly or disassembly ; GO:0006333 | inferred from electronic annotation with InterPro:IPR000953","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with InterPro:IPR000953 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay <newline> chromatin ; GO:0000785 | inferred from electronic annotation with InterPro:IPR000953","ATP-dependent helicase activity ; GO:0008026 | inferred from sequence or structural similarity with InterPro:IPR001410 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330, InterPro:IPR001650 <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000330 <newline> chromatin binding ; GO:0003682 | inferred from electronic annotation with InterPro:IPR000953"]
[null,"FBgn0003277","RNA polymerase II 215kD subunit","RpII215","The gene RNA polymerase II 215kD subunit is referred to in FlyBase by the symbol Dmel\\RpII215 (CG1554, FBgn0003277). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: DNA-directed RNA polymerase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transcription from RNA polymerase II promoter. 173 alleles are reported. The phenotypes of these alleles are annotated with: haltere; capitellum. It has one annotated transcript and one annotated polypeptide. Protein features are: RNA polymerase II, heptapeptide repeat, eukaryotic; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 5; RNA polymerase Rpb1, domain 6; RNA polymerase Rpb1, domain 7; RNA polymerase, N-terminal; RNA polymerase, alpha subunit. Gene sequence location is X:11456806..11464355.","transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC_gene:POLR2A; HGNC:9187; OMIM:180660 AND inferred from sequence or structural similarity with SGD_LOCUS:RPO21; SGD:S0002299 AND inferred from sequence or structural similarity with WB:ama-1; WP:CE28300 <newline> transcription from RNA polymerase II promoter ; GO:0006366 | non-traceable author statement","DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC_gene:POLR2A; HGNC:9187; OMIM:180660 AND inferred from sequence or structural similarity with SGD_LOCUS:RPO21; SGD:S0002299 AND inferred from sequence or structural similarity with WB:ama-1; WP:CE28300 <newline> DNA-directed RNA polymerase II, core complex ; GO:0005665 | non-traceable author statement <newline> polytene chromosome puff ; GO:0005703 | inferred from direct assay","DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity with HGNC_gene:POLR2A; HGNC:9187; OMIM:180660 AND inferred from sequence or structural similarity with SGD_LOCUS:RPO21; SGD:S0002299 AND inferred from sequence or structural similarity with WB:ama-1; WP:CE28300 <newline> DNA-directed RNA polymerase activity ; GO:0003899 | non-traceable author statement <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000684, InterPro:IPR000722, InterPro:IPR006592, InterPro:IPR007066, InterPro:IPR007073, InterPro:IPR007075, InterPro:IPR007080, InterPro:IPR007081, InterPro:IPR007083"]
[]
["Other Transcription factors"]
[null,"FBgn0010575","scribbler","sbb","The gene scribbler is referred to in FlyBase by the symbol Dmel\\sbb (CG5580, FBgn0010575). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: transcription corepressor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of gene-specific transcription from RNA polymerase II promoter; axon guidance; wing disc dorsal/ventral pattern formation; imaginal disc-derived wing morphogenesis; axon target recognition; regulation of imaginal disc growth; negative regulation of smoothened signaling pathway; larval locomotory behavior. 93 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: peripheral nervous system; adult segment; organ system; nervous system; integumentary plate; thoracic segment; multi-cell-component structure; adult mesothoracic segment; synaptic neuropil subdomain; dorsal thoracic disc. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Zinc finger, C2H2-like; Zinc finger, C2H2-type. Gene sequence location is 2R:14166570..14244766.","axon target recognition ; GO:0007412 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | non-traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement <newline> photoreceptor cell development ; GO:0042461 | non-traceable author statement <newline> larval locomotory behavior ; GO:0008345 | traceable author statement <newline> regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> negative regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010553 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","sequence-specific DNA binding transcription factor activity ; GO:0003700 | non-traceable author statement <newline> transcription corepressor activity ; GO:0003714 | inferred from direct assay <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0000448","Hormone receptor-like in 46","Hr46","The gene Hormone receptor-like in 46 is referred to in FlyBase by the symbol Dmel\\Hr46 (CG33183, FBgn0000448). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6092959..6124853. It has the cytological map location 46F5-46F7. There is experimental evidence that it has the molecular function</span>: protein binding; ligand-dependent nuclear receptor activity. There is experimental evidence that it is involved in the biological process</span>: mushroom body development. 56 alleles are reported. The phenotypes of these alleles are annotated with: taenidial fold; mushroom body; embryonic peripheral nervous system; adult head; puparium. It has 4 annotated transcripts and 4 annotated polypeptides.","regulation of development, heterochronic ; GO:0040034 | traceable author statement <newline> metamorphosis ; GO:0007552 | traceable author statement <newline> mushroom body development ; GO:0016319 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000324, InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR001723, InterPro:IPR008946, InterPro:IPR013088","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q8R1B8 <newline> nucleus ; GO:0005634 | non-traceable author statement","ligand-dependent nuclear receptor activity ; GO:0004879 | inferred from direct assay <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | inferred from sequence or structural similarity with UniProtKB:Q8R1B8 <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with MGD:Rora; MGI:MGI:104661 <newline> protein binding ; GO:0005515 | inferred from physical interaction with rig <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | non-traceable author statement <newline> steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR000536, InterPro:IPR008946 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628"]
[null,"FBgn0000472","diminutive","dm","The gene diminutive is referred to in FlyBase by the symbol Dmel\\dm (CG10798, FBgn0000472). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3267216..3280049. It has the cytological map location 3D2. There is experimental evidence that it has the molecular function</span>: transcription factor activity; protein binding; DNA binding. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: regulation of biological process; regulation of metabolic process; multicellular organismal development; regulation of growth; embryonic development; cell proliferation; embryonic development ending in birth or egg hatching; cell cycle; regulation of apoptosis; positive regulation of cellular biosynthetic process; anatomical structure development; cellular process; embryonic pattern specification; negative regulation of Notch signaling pathway. 55 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; peripheral nervous system; nervous system; external compound sense organ; female germline cyst; cell cycle; nucleus; thoracic segment; imaginal precursor; intracellular membrane-bounded organelle. It has one annotated transcript and one annotated polypeptide.","regulation of transcription, DNA-dependent ; GO:0006355 | inferred from direct assay <newline> cell proliferation ; GO:0008283 | inferred from expression pattern <newline> embryonic development ending in birth or egg hatching ; GO:0009792 | inferred from expression pattern <newline> positive regulation of cell growth ; GO:0030307 | traceable author statement <newline> positive regulation of growth ; GO:0045927 | traceable author statement <newline> regulation of cell size ; GO:0008361 | traceable author statement <newline> positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement <newline> DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype <newline> cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype <newline> regulation of organ growth ; GO:0046620 | inferred from mutant phenotype <newline> regulation of cell growth ; GO:0001558 | inferred from mutant phenotype <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | traceable author statement <newline> regulation of cell cycle ; GO:0051726 | traceable author statement <newline> positive regulation of transcription ; GO:0045941 | inferred from mutant phenotype <newline> neurogenesis ; GO:0022008 | inferred from genetic interaction with Egfr <newline> embryonic pattern specification ; GO:0009880 | inferred from genetic interaction with Egfr <newline> negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with N <newline> regulation of apoptosis ; GO:0042981 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:L00039 <newline> protein complex ; GO:0043234 | inferred from physical interaction with gro","DNA binding ; GO:0003677 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:L00039 <newline> protein binding ; GO:0005515 | inferred from physical interaction with lid <newline> protein binding ; GO:0005515 | inferred from physical interaction with gro"]
[null,"FBgn0000504","doublesex","dsx","The gene doublesex is referred to in FlyBase by the symbol Dmel\\dsx (CG11094, FBgn0000504). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3750045..3793130. It has the cytological map location 84E5-84E6. There is experimental evidence that it has the molecular function</span>: protein binding; protein homodimerization activity. There is experimental evidence that it is involved in the biological process</span>: imaginal disc-derived female genitalia development; imaginal disc-derived male genitalia development; genital disc development. 116 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; adult segment; region of integument; adult; peripheral nervous system; imaginal precursor; nervous system; hub cell; larval abdominal segment 8; male accessory gland; female genitalia; external compound sense organ; female germline cyst. It has 3 annotated transcripts and 3 annotated polypeptides.","imaginal disc-derived female genitalia development ; GO:0007486 | inferred from genetic interaction with tra2 <newline> genital disc development ; GO:0035215 | inferred from mutant phenotype <newline> imaginal disc-derived male genitalia development ; GO:0007485 | inferred from genetic interaction with tra2 <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | non-traceable author statement <newline> positive regulation of transcription, DNA-dependent ; GO:0045893 | non-traceable author statement <newline> female somatic sex determination ; GO:0019101 | traceable author statement <newline> spermatogenesis ; GO:0007283 | non-traceable author statement <newline> sex determination ; GO:0007530 | non-traceable author statement <newline> somatic sex determination ; GO:0018993 | non-traceable author statement <newline> transcription from RNA polymerase II promoter ; GO:0006366 | non-traceable author statement <newline> sex differentiation ; GO:0007548 | non-traceable author statement <newline> courtship behavior ; GO:0007619 | non-traceable author statement <newline> male courtship behavior, veined wing generated song production ; GO:0045433 | non-traceable author statement <newline> female somatic sex determination ; GO:0019101 | non-traceable author statement <newline> male courtship behavior, veined wing generated song production ; GO:0045433 | traceable author statement <newline> male somatic sex determination ; GO:0019102 | non-traceable author statement <newline> female analia development ; GO:0045497 | non-traceable author statement <newline> imaginal disc-derived female genitalia development ; GO:0007486 | non-traceable author statement <newline> genital disc development ; GO:0035215 | traceable author statement <newline> genital disc sexually dimorphic development ; GO:0035263 | traceable author statement <newline> male analia development ; GO:0045496 | non-traceable author statement <newline> imaginal disc-derived male genitalia development ; GO:0007485 | non-traceable author statement <newline> sex comb development ; GO:0045498 | traceable author statement <newline> female sex differentiation ; GO:0046660 | traceable author statement <newline> sex-specific pigmentation ; GO:0048071 | traceable author statement <newline> central nervous system development ; GO:0007417 | traceable author statement <newline> sex differentiation ; GO:0007548 | traceable author statement <newline> sex-specific pigmentation ; GO:0048071 | non-traceable author statement <newline> genital disc morphogenesis ; GO:0007483 | traceable author statement <newline> negative regulation of developmental pigmentation ; GO:0048086 | traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | traceable author statement <newline> regulation of imaginal disc growth ; GO:0045570 | traceable author statement <newline> somatic sex determination ; GO:0018993 | traceable author statement <newline> behavior ; GO:0007610 | traceable author statement <newline> sex determination ; GO:0007530 | traceable author statement <newline> male sex differentiation ; GO:0046661 | traceable author statement <newline> nuclear mRNA splicing, via spliceosome ; GO:0000398 | traceable author statement <newline> regulation of transcription ; GO:0045449 | traceable author statement <newline> male courtship behavior ; GO:0008049 | traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001275","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:AF130728; protein_id:AAD40474.1","specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from sequence or structural similarity with EMBL:AF130728; protein_id:AAD40474.1 <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | non-traceable author statement <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | traceable author statement <newline> DNA binding ; GO:0003677 | traceable author statement <newline> mRNA binding ; GO:0003729 | non-traceable author statement <newline> transcription regulator activity ; GO:0030528 | traceable author statement <newline> protein homodimerization activity ; GO:0042803 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with ix <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001275"]
[null,"FBgn0000567","Ecdysone-induced protein 74EF","Eip74EF","The gene Ecdysone-induced protein 74EF is referred to in FlyBase by the symbol Dmel\\Eip74EF (CG32180, FBgn0000567). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:17553258..17612407. It has the cytological map location 74D4-74E2. Based on sequence similarity, it is predicted to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: cellular process; autophagy; salivary gland cell autophagic cell death. 43 alleles are reported. The phenotypes of these alleles are annotated with: larva; salivary gland; adult epidermis; cuticle; air bubble; procephalic segment; anterior pupal spiracle. It has 4 annotated transcripts and 4 annotated polypeptides.","salivary gland cell autophagic cell death ; GO:0035071 | non-traceable author statement <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype <newline> autophagy ; GO:0006914 | inferred from mutant phenotype <newline> cell death ; GO:0008219 | traceable author statement <newline> regulation of transcription ; GO:0045449 | non-traceable author statement <newline> regulation of development, heterochronic ; GO:0040034 | traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from sequence or structural similarity with UniProtKB:Q15725 <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | non-traceable author statement","nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGD:Elf1; MGI:MGI:107180 <newline> nucleus ; GO:0005634 | non-traceable author statement","transcription factor activity ; GO:0003700 | traceable author statement <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from sequence or structural similarity with UniProtKB:Q15725 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR000418 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000418"]
[null,"FBgn0000568","Ecdysone-induced protein 75B","Eip75B","The gene Ecdysone-induced protein 75B is referred to in FlyBase by the symbol Dmel\\Eip75B (CG8127, FBgn0000568). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:17945063..18052698. It has the cytological map location 75A10-75B6. There is experimental evidence that it has the molecular function</span>: heme binding. There is experimental evidence that it is involved in the biological process</span>: molting cycle, chitin-based cuticle; antimicrobial humoral response; ecdysis, chitin-based cuticle; regulation of ecdysteroid metabolic process. 136 alleles are reported. The phenotypes of these alleles are annotated with: eye; midgut chamber 3; midgut constriction 1; larval anterior spiracle; wing; mouth hooks. It has 4 annotated transcripts and 4 annotated polypeptides.","ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | non-traceable author statement <newline> ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype <newline> molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype <newline> regulation of ecdysteroid metabolic process ; GO:0007553 | inferred from mutant phenotype <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> molting cycle, chitin-based cuticle ; GO:0007591 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> oogenesis ; GO:0048477 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000324, InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR001723, InterPro:IPR003079, InterPro:IPR008946, InterPro:IPR013088","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:U09504 <newline> nucleus ; GO:0005634 | non-traceable author statement","ligand-dependent nuclear receptor activity ; GO:0004879 | inferred from sequence or structural similarity with EMBL:U09504 <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from sequence or structural similarity with EMBL:U09504 <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | non-traceable author statement <newline> heme binding ; GO:0020037 | inferred from direct assay <newline> steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR000536, InterPro:IPR008946 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR008946, InterPro:IPR013088"]
[null,"FBgn0000625","eyegone","eyg","The gene eyegone is referred to in FlyBase by the symbol Dmel\\eyg (CG10488, FBgn0000625). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:12456132..12461121. It has the cytological map location 69C2. There is experimental evidence that it has the molecular function</span>: transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: notum development; eye development; antennal development; eye-antennal disc development; compound eye development; compound eye morphogenesis. 54 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: adult segment; adult mesothoracic segment; peripheral nervous system; nervous system; organ system; imaginal precursor; external compound sense organ; integumentary plate; salivary gland imaginal ring; dorsal thoracic disc. It has 2 annotated transcripts and 2 annotated polypeptides.","eye development ; GO:0001654 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> antennal development ; GO:0007469 | inferred from mutant phenotype <newline> notum development ; GO:0007477 | inferred from mutant phenotype <newline> eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970","transcription factor complex ; GO:0005667 | inferred from sequence or structural similarity with MGD:Pax3; MGI:MGI:97487","transcription repressor activity ; GO:0016564 | inferred from mutant phenotype <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with MGD:Pax3; MGI:MGI:97487 <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970"]
[null,"FBgn0001138","grain","grn","The gene grain is referred to in FlyBase by the symbol Dmel\\grn (CG9656, FBgn0001138). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3973072..4007164. It has the cytological map location 84F1. Based on sequence similarity, it is predicted to have molecular function</span>: general RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: tissue development; organ morphogenesis. 13 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; embryonic abdomen; cephalopharyngeal skeleton; embryonic segment; cuticle; embryonic neuron; spiracle; pharyngeal sclerite; embryonic nervous system; integumentary specialisation. It has 2 annotated transcripts and 2 annotated polypeptides.","organ morphogenesis ; GO:0009887 | inferred from mutant phenotype <newline> tissue development ; GO:0009888 | inferred from mutant phenotype <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with UniProtKB:P23770 <newline> organ morphogenesis ; GO:0009887 | non-traceable author statement <newline> tissue development ; GO:0009888 | non-traceable author statement","nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGD:Gata3; MGI:MGI:95663","general RNA polymerase II transcription factor activity ; GO:0016251 | non-traceable author statement <newline> general RNA polymerase II transcription factor activity ; GO:0016251 | inferred from sequence or structural similarity with UniProtKB:P23770 <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR000679 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000679, InterPro:IPR013088 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000679, InterPro:IPR013088"]
[null,"FBgn0001269","invected","inv","The gene invected is referred to in FlyBase by the symbol Dmel\\inv (CG17835, FBgn0001269). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7361970..7394688. It has the cytological map location 47F15-47F17. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: neuroblast fate determination; compartment specification. 37 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; thoracic segment; adult; cuticle; multi-cell-component structure; embryonic hindgut; embryonic nervous system; nervous system; region of integument; developing anatomical structure. It has 4 annotated transcripts and 4 annotated polypeptides.","compartment pattern formation ; GO:0007386 | inferred from mutant phenotype AND inferred from sequence or structural similarity with en <newline> neuroblast fate determination ; GO:0007400 | inferred from genetic interaction with en, gsb AND inferred from genetic interaction with en, gsb, ptc <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with EMBL:AF213356 <newline> compartment pattern formation ; GO:0007386 | traceable author statement <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | traceable author statement","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q05925 <newline> nucleus ; GO:0005634 | non-traceable author statement","RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity with EMBL:AF213356 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000047, InterPro:IPR001356"]
[null,"FBgn0001297","kayak","kay","The gene kayak is referred to in FlyBase by the symbol Dmel\\kay (CG33956, FBgn0001297). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25592497..25619838. It has the cytological map location 99B10-99C1. There is experimental evidence that it has the molecular function</span>: protein binding; sequence-specific DNA binding; RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; sensory organ development; response to stress; organ development; organ morphogenesis; cell cycle; cellular component movement; response to external stimulus; regulation of cyclin-dependent protein kinase activity; ovarian follicle cell development; immune response; embryonic development via the syncytial blastoderm; wound healing. 47 alleles are reported. The phenotypes of these alleles are annotated with 44 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; nervous system; embryonic nervous system; external compound sense organ; peripheral nervous system; multi-cell-component structure; imaginal precursor; thoracic segment. It has 4 annotated transcripts and 4 annotated polypeptides.","regulation of cyclin-dependent protein kinase activity during G2/M ; GO:0031660 | inferred from mutant phenotype <newline> second mitotic wave during compound eye morphogenesis ; GO:0016330 | inferred from mutant phenotype <newline> wing disc development ; GO:0035220 | inferred from mutant phenotype <newline> central nervous system development ; GO:0007417 | inferred from mutant phenotype <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> midgut development ; GO:0007494 | inferred from mutant phenotype <newline> JNK cascade ; GO:0007254 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> imaginal disc fusion, thorax closure ; GO:0046529 | traceable author statement <newline> ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype <newline> response to wounding ; GO:0009611 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | non-traceable author statement <newline> R3/R4 cell fate commitment ; GO:0007464 | traceable author statement <newline> establishment of planar polarity ; GO:0001736 | non-traceable author statement <newline> wound healing ; GO:0042060 | inferred from mutant phenotype <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Pvr <newline> R3/R4 cell fate commitment ; GO:0007464 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR004827, InterPro:IPR011616","nucleus ; GO:0005634 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","sequence-specific DNA binding ; GO:0043565 | inferred from direct assay <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | traceable author statement <newline> transcription factor binding ; GO:0008134 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with Cka <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> transcription factor binding ; GO:0008134 | non-traceable author statement <newline> protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity <newline> protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011616 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR004827, InterPro:IPR011616"]
[null,"FBgn0001323","knirps-like","knrl","The gene knirps-like is referred to in FlyBase by the symbol Dmel\\knrl (CG4761, FBgn0001323). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20590241..20613636. It has the cytological map location 77D4-77E1. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity; ligand-dependent nuclear receptor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of mitosis. 6 alleles are reported. The phenotypes of these alleles are annotated with: dorsal closure embryo; metathoracic femur; embryonic dorsal epidermis. It has one annotated transcript and one annotated polypeptide.","regulation of mitosis ; GO:0007088 | inferred from mutant phenotype <newline> epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> regulation of tube size, open tracheal system ; GO:0035151 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000324, InterPro:IPR001628, InterPro:IPR013088","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q60674 <newline> nucleus ; GO:0005634 | non-traceable author statement","ligand-dependent nuclear receptor activity ; GO:0004879 | inferred from sequence or structural similarity with UniProtKB:Q60674 <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with UniProtKB:Q60674 <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628"]
[null,"FBgn0002643","mastermind","mam","The gene mastermind is referred to in FlyBase by the symbol Dmel\\mam (CG8118, FBgn0002643). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9878686..9947861. It has the cytological map location 50C23-50D3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: transcription coactivator activity. There is experimental evidence that it is involved in the biological process</span>: germ-line stem cell maintenance; heart morphogenesis; apposition of dorsal and ventral imaginal disc-derived wing surfaces; mesodermal cell fate determination; imaginal disc-derived wing margin morphogenesis; somatic stem cell maintenance; bristle morphogenesis; imaginal disc-derived wing morphogenesis; asymmetric cell division. 194 alleles are reported. The phenotypes of these alleles are annotated with 73 unique terms, many of which group under: synaptic neuropil subdomain; adult segment; antennal segment; embryonic nervous system; adult mesothoracic segment; embryonic neuron; peripheral nervous system; embryonic glial cell; germarium; external compound sense organ. It has 3 annotated transcripts and 3 annotated polypeptides.","ectoderm development ; GO:0007398 | traceable author statement <newline> mesodermal cell fate determination ; GO:0007500 | inferred from mutant phenotype <newline> apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> asymmetric cell division ; GO:0008356 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | traceable author statement <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> heart morphogenesis ; GO:0003007 | inferred from mutant phenotype <newline> somatic stem cell maintenance ; GO:0035019 | inferred from mutant phenotype <newline> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from electronic annotation with InterPro:IPR019082 <newline> Notch signaling pathway ; GO:0007219 | inferred from electronic annotation with InterPro:IPR019082","nucleus ; GO:0005634 | inferred from direct assay AND inferred from sequence or structural similarity <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nuclear speck ; GO:0016607 | inferred from electronic annotation with InterPro:IPR019082","transcription coactivator activity ; GO:0003713 | inferred from electronic annotation with InterPro:IPR019082"]
[null,"FBgn0002733","E(spl) region transcript mbeta","HLHmbeta","The gene E(spl) region transcript m? is referred to in FlyBase by the symbol Dmel\\HLHm? (CG14548, FBgn0002733). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21830648..21831745. It has the cytological map location 96F9. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: negative regulation of transcription from RNA polymerase II promoter. 7 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; wing margin bristle; macrochaeta; anterior crossvein; scutellar bristle; microchaeta; wing vein. It has one annotated transcript and one annotated polypeptide.","negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> negative regulation of transcription ; GO:0016481 | non-traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> compound eye development ; GO:0048749 | traceable author statement","nucleus ; GO:0005634 | inferred by curator from GO:0003677 <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR011598","transcription factor activity ; GO:0003700 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> transcription repressor activity ; GO:0016564 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from direct assay"]
[null,"FBgn0002735","E(spl) region transcript mgamma","HLHmgamma","The gene E(spl) region transcript m? is referred to in FlyBase by the symbol Dmel\\HLHm? (CG8333, FBgn0002735). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21825580..21826421. It has the cytological map location 96F9. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding; transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of transcription; wing disc dorsal/ventral pattern formation. 10 alleles are reported. The phenotypes of these alleles are annotated with: adult thorax; wing margin bristle; macrochaeta; scutellar bristle; microchaeta; wing vein. It has one annotated transcript and one annotated polypeptide.","negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> negative regulation of transcription ; GO:0016481 | non-traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> compound eye development ; GO:0048749 | traceable author statement <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> negative regulation of transcription ; GO:0016481 | inferred from direct assay","nucleus ; GO:0005634 | inferred by curator from GO:0003677 <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR011598","transcription factor activity ; GO:0003700 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> transcription repressor activity ; GO:0016564 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | inferred from direct assay <newline> sequence-specific DNA binding ; GO:0043565 | inferred from direct assay"]
[null,"FBgn0003028","ovo","ovo","The gene ovo is referred to in FlyBase by the symbol Dmel\\ovo (CG6824, FBgn0003028). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:4942330..4964962. It has the cytological map location 4E2. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding; transcription repressor activity; transcription activator activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: pheromone metabolic process; cuticle pigmentation; non-sensory hair organization; positive regulation of transcription from RNA polymerase II promoter; cuticle pattern formation; germ-line sex determination; negative regulation of transcription from RNA polymerase II promoter; adult feeding behavior; epidermal cell differentiation. 186 alleles are reported. The phenotypes of these alleles are annotated with 28 unique terms, many of which group under: organ system; female germline cyst; adult segment; cuticle; peripheral nervous system; external compound sense organ; egg; antennal segment; nervous system; cell part. It has 5 annotated transcripts and 5 annotated polypeptides.","cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype <newline> cuticle pigmentation ; GO:0048067 | inferred from mutant phenotype <newline> epidermal cell differentiation ; GO:0009913 | inferred from mutant phenotype <newline> non-sensory hair organization ; GO:0035316 | inferred from mutant phenotype <newline> non-sensory hair organization ; GO:0035316 | traceable author statement <newline> regulation of transcription ; GO:0045449 | traceable author statement <newline> pheromone metabolic process ; GO:0042810 | inferred from mutant phenotype <newline> female germ-line sex determination ; GO:0019099 | non-traceable author statement <newline> cuticle development ; GO:0042335 | traceable author statement <newline> oogenesis ; GO:0048477 | traceable author statement <newline> germ-line sex determination ; GO:0018992 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:P19339 <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype <newline> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype <newline> adult feeding behavior ; GO:0008343 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q60821 <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred by curator from GO:0003677","sequence-specific DNA binding ; GO:0043565 | inferred from direct assay <newline> DNA binding ; GO:0003677 | traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity with UniProtKB:Q60821 <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> transcription repressor activity ; GO:0016564 | inferred from mutant phenotype <newline> transcription activator activity ; GO:0016563 | inferred from mutant phenotype <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0003165","pumilio","pum","The gene pumilio is referred to in FlyBase by the symbol Dmel\\pum (CG9755, FBgn0003165). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4895479..5063417. It has the cytological map location 85C4-85D1. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: regulation of synaptic transmission; synaptic transmission; dendrite morphogenesis; pole cell migration; long-term memory; head involution; regulation of synaptic growth at neuromuscular junction. 130 alleles are reported. The phenotypes of these alleles are annotated with 41 unique terms, many of which group under: organ system; embryonic abdomen; embryonic segment; female germline cyst; anatomical structure; nervous system; peripheral nervous system; germarium; embryonic tagma; embryonic neuron; multi-cell-component structure; cephalopharyngeal skeleton. It has 5 annotated transcripts and 5 annotated polypeptides.","regulation of synaptic transmission ; GO:0050804 | inferred from mutant phenotype <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from mutant phenotype <newline> cell fate determination ; GO:0001709 | traceable author statement <newline> germ cell development ; GO:0007281 | traceable author statement <newline> germ-line stem cell division ; GO:0042078 | traceable author statement <newline> synaptic transmission ; GO:0007268 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> pole cell migration ; GO:0007280 | inferred from mutant phenotype <newline> germ-line stem cell division ; GO:0042078 | non-traceable author statement <newline> cell migration ; GO:0016477 | traceable author statement <newline> anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement <newline> nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ; GO:0000288 | traceable author statement <newline> mitosis ; GO:0007067 | traceable author statement <newline> negative regulation of cell cycle ; GO:0045786 | traceable author statement <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | traceable author statement <newline> pole cell migration ; GO:0007280 | traceable author statement <newline> long-term memory ; GO:0007616 | traceable author statement <newline> negative regulation of translation ; GO:0017148 | traceable author statement <newline> positive regulation of translation ; GO:0045727 | traceable author statement <newline> oogenesis ; GO:0048477 | traceable author statement <newline> regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from direct assay","cytoplasm ; GO:0005737 | non-traceable author statement","mRNA 3'-UTR binding ; GO:0003730 | traceable author statement <newline> protein binding ; GO:0005515 | traceable author statement <newline> mRNA binding ; GO:0003729 | inferred from sequence or structural similarity with EMBL:AF315592; protein_id:AAG31807.1 AND inferred from sequence or structural similarity with MGD:Pum2; MGI:MGI:1931751 AND traceable author statement <newline> translation repressor activity, nucleic acid binding ; GO:0000900 | traceable author statement"]
[null,"FBgn0003396","schnurri","shn","The gene schnurri is referred to in FlyBase by the symbol Dmel\\shn (CG7734, FBgn0003396). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7061325..7104918. It has the cytological map location 47D6-47D7. There is experimental evidence that it has the molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: olfactory learning; ectoderm development; learning or memory; cell proliferation; imaginal disc-derived wing vein morphogenesis; wing disc anterior/posterior pattern formation; wing disc dorsal/ventral pattern formation; imaginal disc-derived wing morphogenesis; midgut development. 108 alleles are reported. The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; peripheral nervous system; adult segment; embryonic nervous system; adult mesothoracic segment; nervous system; external compound sense organ; primordium; embryonic peripheral nervous system; embryonic head; midgut constriction; podocyte; organ system subdivision; multi-cell-component structure; spiracle. It has 4 annotated transcripts and 4 annotated polypeptides.","ectoderm development ; GO:0007398 | inferred from mutant phenotype <newline> midgut development ; GO:0007494 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from mutant phenotype <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from genetic interaction with dpp AND inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> learning or memory ; GO:0007611 | inferred from mutant phenotype <newline> olfactory learning ; GO:0008355 | inferred from mutant phenotype <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement <newline> negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement <newline> compound eye morphogenesis ; GO:0001745 | non-traceable author statement <newline> negative regulation of cell proliferation ; GO:0008285 | non-traceable author statement <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap","nucleus ; GO:0005634 | non-traceable author statement <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:X51435; protein_id:CAA35798.1 <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from mutant phenotype <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003604, InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0003749","trachealess","trh","The gene trachealess is referred to in FlyBase by the symbol Dmel\\trh (CG6883, FBgn0003749). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:366524..377316. It has the cytological map location 61C1. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding; transcription activator activity; RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: epithelial cell fate determination, open tracheal system; Malpighian tubule morphogenesis; spiracle morphogenesis, open tracheal system; dendrite morphogenesis; salivary gland development; open tracheal system development; salivary gland morphogenesis. 27 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; embryonic/larval tracheal system; portion of tissue; tracheal system; anatomical structure; Malpighian tubule; integumentary system; embryonic/larval dorsal branch; Malpighian tubule segment; embryonic tracheal system; primordium; spiracle; embryonic trachea. It has 2 annotated transcripts and 2 annotated polypeptides.","regulation of transcription, DNA-dependent ; GO:0006355 | inferred from sequence or structural similarity with UniProtKB:P05709 <newline> salivary gland development ; GO:0007431 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> epithelial cell fate determination, open tracheal system ; GO:0007425 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> salivary gland development ; GO:0007431 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | non-traceable author statement <newline> epithelial cell fate determination, open tracheal system ; GO:0007425 | traceable author statement <newline> salivary gland morphogenesis ; GO:0007435 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:U22431; protein_id:AAC50152 AND inferred from sequence or structural similarity with sim <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | traceable author statement","RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity with EMBL:U22431; protein_id:AAC50152 AND inferred from sequence or structural similarity with sim <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from mutant phenotype AND inferred from sequence or structural similarity with sim <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> protein heterodimerization activity ; GO:0046982 | traceable author statement <newline> transcription factor activity ; GO:0003700 | traceable author statement <newline> transcription activator activity ; GO:0016563 | inferred from direct assay <newline> sequence-specific DNA binding ; GO:0043565 | inferred from direct assay"]
[null,"FBgn0003870","tramtrack","ttk","The gene tramtrack is referred to in FlyBase by the symbol Dmel\\ttk (CG1856, FBgn0003870). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27539591..27561114. It has the cytological map location 100D1. There is experimental evidence that it has the molecular function</span>: protein binding; specific transcriptional repressor activity; chromatin binding; protein homodimerization activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; inter-male aggressive behavior; startle response; brain morphogenesis; dendrite morphogenesis; neuron development; ovarian follicle cell development; negative regulation of transcription, DNA-dependent; dorsal appendage formation; locomotion involved in locomotory behavior. 153 alleles are reported. The phenotypes of these alleles are annotated with 70 unique terms, many of which group under: peripheral nervous system; nervous system; external compound sense organ; adult segment; embryonic nervous system; multi-cell-component structure; adult mesothoracic segment; embryonic glial cell; imaginal precursor; larval abdominal segment 5. It has 8 annotated transcripts and 8 annotated polypeptides.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> R7 cell development ; GO:0045467 | traceable author statement <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> cell fate determination ; GO:0001709 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> brain morphogenesis ; GO:0048854 | inferred from mutant phenotype <newline> startle response ; GO:0001964 | inferred from mutant phenotype <newline> locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | inferred from direct assay <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype","polytene chromosome ; GO:0005700 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with CoRest <newline> chromatin binding ; GO:0003682 | inferred from direct assay <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> protein homodimerization activity ; GO:0042803 | inferred from physical interaction with UniProtKB:P17789 <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q08605 <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR017956 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0003964","ultraspiracle","usp","The gene ultraspiracle is referred to in FlyBase by the symbol Dmel\\usp (CG4380, FBgn0003964). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1932831..1935343. It has the cytological map location 2C7. There is experimental evidence that it has the molecular function</span>: ecdysteroid hormone receptor activity; protein binding; lipid binding; protein heterodimerization activity; protein homodimerization activity. There is experimental evidence that it is involved in the biological process</span>: border follicle cell migration; dendrite morphogenesis; neuron development; neuron remodeling; muscle organ development. 22 alleles are reported. The phenotypes of these alleles are annotated with: dendrite; terminal filament; embryonic/larval anterior spiracle; midgut imaginal island; dorsal multidendritic neuron ddaC; imaginal disc. It has one annotated transcript and one annotated polypeptide.","neuron remodeling ; GO:0016322 | inferred from mutant phenotype <newline> ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | non-traceable author statement <newline> metamorphosis ; GO:0007552 | non-traceable author statement <newline> negative regulation of cell differentiation ; GO:0045596 | traceable author statement <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | traceable author statement <newline> regulation of development, heterochronic ; GO:0040034 | traceable author statement <newline> positive regulation of transcription ; GO:0045941 | traceable author statement <newline> dendrite morphogenesis ; GO:0048813 | non-traceable author statement <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000324, InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR001723, InterPro:IPR008946, InterPro:IPR013088","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P51128 <newline> ecdysone receptor holocomplex ; GO:0008230 | traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> polytene chromosome ; GO:0005700 | non-traceable author statement <newline> dendrite ; GO:0030425 | inferred from mutant phenotype","ecdysteroid hormone receptor activity ; GO:0004884 | inferred from direct assay <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | inferred from sequence or structural similarity with UniProtKB:P51128 <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with UniProtKB:P51128 <newline> protein binding ; GO:0005515 | inferred from physical interaction with rig <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> ecdysteroid hormone receptor activity ; GO:0004884 | non-traceable author statement <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | non-traceable author statement <newline> juvenile hormone binding ; GO:0005500 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with egg <newline> lipid binding ; GO:0008289 | inferred from direct assay <newline> protein homodimerization activity ; GO:0042803 | inferred from direct assay <newline> protein heterodimerization activity ; GO:0046982 | inferred from direct assay <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628"]
[null,"FBgn0004101","blistered","bs","The gene blistered is referred to in FlyBase by the symbol Dmel\\bs (CG3411, FBgn0004101). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20231236..20263998. It has the cytological map location 60C6-60C7. It is reported to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: apposition of dorsal and ventral imaginal disc-derived wing surfaces; terminal branching, open tracheal system; imaginal disc-derived wing morphogenesis; sleep; open tracheal system development. 61 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; thoracic segment; tracheal system; embryonic/larval tracheal system; appendage segment; cuticle; wing cell; embryonic tracheal system; organ system subdivision; cephalopharyngeal skeleton; peripheral nervous system. It has 2 annotated transcripts and 2 annotated polypeptides.","open tracheal system development ; GO:0007424 | inferred from expression pattern <newline> terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype <newline> terminal branching, open tracheal system ; GO:0007430 | traceable author statement <newline> apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype <newline> cell fate commitment ; GO:0045165 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> terminal cell fate specification, open tracheal system ; GO:0035154 | traceable author statement <newline> open tracheal system development ; GO:0007424 | non-traceable author statement <newline> terminal branching, open tracheal system ; GO:0007430 | non-traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> sleep ; GO:0030431 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR002100","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR002100 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR002100"]
[null,"FBgn0004656","female sterile (1) homeotic","fs(1)h","The gene female sterile (1) homeotic is referred to in FlyBase by the symbol Dmel\\fs(1)h (CG2252, FBgn0004656). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7933976..7955469. It has the cytological map location 7D3-7D5. It is reported to have molecular function</span>: protein kinase activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: terminal region determination; negative regulation of gene-specific transcription. 51 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; embryonic head; cephalopharyngeal skeleton; egg; metathoracic segment; mouth hooks; hypostomal sclerite. It has 6 annotated transcripts and 6 annotated polypeptides.","regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> terminal region determination ; GO:0007362 | inferred from mutant phenotype <newline> negative regulation of gene-specific transcription ; GO:0032582 | inferred from mutant phenotype","-","DNA binding ; GO:0003677 | non-traceable author statement <newline> protein kinase activity ; GO:0004672 | non-traceable author statement"]
[null,"FBgn0004914","Hepatocyte nuclear factor 4","Hnf4","The gene Hepatocyte nuclear factor 4 is referred to in FlyBase by the symbol Dmel\\Hnf4 (CG9310, FBgn0004914). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:8687281..8709038. It has the cytological map location 29E4. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity; ligand-dependent nuclear receptor activity. There is experimental evidence that it is involved in the biological process</span>: lipid catabolic process; lipid oxidation. 24 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides.","lipid biosynthetic process ; GO:0008610 | non-traceable author statement <newline> endoderm development ; GO:0007492 | non-traceable author statement <newline> mesoderm development ; GO:0007498 | non-traceable author statement <newline> lipid catabolic process ; GO:0016042 | inferred from direct assay <newline> lipid oxidation ; GO:0034440 | inferred from direct assay <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000003, InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR001723, InterPro:IPR008946, InterPro:IPR013088","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P79926 <newline> nucleus ; GO:0005634 | non-traceable author statement","ligand-dependent nuclear receptor activity ; GO:0004879 | inferred from sequence or structural similarity with UniProtKB:P79926 <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with UniProtKB:P79926 <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | non-traceable author statement <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR000536, InterPro:IPR008946 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000003, InterPro:IPR001628, InterPro:IPR013088 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 <newline> steroid binding ; GO:0005496 | inferred from electronic annotation with InterPro:IPR000003"]
[null,"FBgn0005511","midline","mid","The gene midline is referred to in FlyBase by the symbol Dmel\\mid (CG6634, FBgn0005511). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:5461641..5467609. It has the cytological map location 25E2. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence for 12 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; regulation of biological process; regulation of developmental process; stem cell differentiation; neuroblast fate commitment; embryonic pattern specification; regulation of metabolic process; regionalization; neuroblast development; regulation of cell fate specification; cellular component movement; embryonic heart tube development; leg disc development; central nervous system development. 15 alleles are reported. The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: organ system; embryonic nervous system; primordium; adult segment; nervous system; cuticle; organ system subdivision; embryonic/larval dorsal vessel; peripheral nervous system; embryonic neuron. It has one annotated transcript and one annotated polypeptide.","segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> heart development ; GO:0007507 | inferred from mutant phenotype <newline> cardioblast cell fate commitment ; GO:0042684 | inferred from mutant phenotype <newline> embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype <newline> regulation of cardioblast differentiation ; GO:0051890 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with EMBL:AC006379; protein_id:AAD21787.1 <newline> neuroblast fate specification ; GO:0014018 | inferred from mutant phenotype <newline> neuroblast development ; GO:0014019 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> central nervous system development ; GO:0007417 | inferred from mutant phenotype inferred from genetic interaction with HGTX <newline> negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype inferred from genetic interaction with HGTX <newline> leg disc pattern formation ; GO:0035223 | inferred from genetic interaction with H15 <newline> regulation of cell fate specification ; GO:0042659 | inferred from genetic interaction with H15 <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001699, InterPro:IPR018186","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:AC006379; protein_id:AAD21787.1","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:AC006379; protein_id:AAD21787.1"]
[null,"FBgn0005612","Sox box protein 14","Sox14","The gene Sox box protein 14 is referred to in FlyBase by the symbol Dmel\\Sox14 (CG3090, FBgn0005612). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19866744..19872700. It has the cytological map location 60A16. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis; neuron remodeling. 7 alleles are reported. The phenotypes of these alleles are annotated with: dendrite; dorsal multidendritic neuron ddaC. It has 2 annotated transcripts and 2 annotated polypeptides.","regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with UniProtKB:Q06945 <newline> dendrite morphogenesis ; GO:0048813 | inferred from genetic interaction with Mical <newline> neuron remodeling ; GO:0016322 | inferred from genetic interaction with Mical","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q06945 <newline> nucleus ; GO:0005634 | non-traceable author statement","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with UniProtKB:Q06945"]
[null,"FBgn0005771","no ocelli","noc","The gene no ocelli is referred to in FlyBase by the symbol Dmel\\noc (CG4491, FBgn0005771). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:14490862..14494019. It has the cytological map location 35B2. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior; eye-antennal disc development; cell proliferation; open tracheal system development. 55 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: peripheral nervous system; nervous system; organ system; adult segment; embryonic/larval tracheal system; integumentary plate; adult mesothoracic segment; embryonic dorsal branch; adult brain; adult external prothorax; embryonic ganglionic branch; postalar bristle. It has one annotated transcript and one annotated polypeptide.","regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from genetic interaction with elB <newline> eye-antennal disc development ; GO:0035214 | inferred from genetic interaction with elB <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0010762","simjang","simj","The gene simjang is referred to in FlyBase by the symbol Dmel\\simj (CG32067, FBgn0010762). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:10657843..10682480. It has the cytological map location 67E6. Based on sequence similarity, it is predicted to have molecular function</span>: transcription repressor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: negative regulation of transcription, DNA-dependent. 51 alleles are reported. The phenotypes of these alleles are annotated with: leg; embryonic heart; scutellar bristle; wing; cardioblast; pupal abdomen. It has 3 annotated transcripts and 3 annotated polypeptides.","negative regulation of transcription, DNA-dependent ; GO:0045892 | inferred from sequence or structural similarity with EMBL:AF411837; protein_id:AAL39081.1","nucleus ; GO:0005634 | inferred from direct assay","transcription repressor activity ; GO:0016564 | inferred from sequence or structural similarity with EMBL:AF411837; protein_id:AAL39081.1"]
[null,"FBgn0001235","homothorax","hth","The gene homothorax is referred to in FlyBase by the symbol Dmel\\hth (CG17117, FBgn0001235). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:6335569..6464386. It has the cytological map location 86C1-86C3. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of gene-specific transcription from RNA polymerase II promoter; compound eye development; specification of segmental identity, antennal segment; specification of segmental identity, head; segmentation; compound eye photoreceptor fate commitment; brain development; imaginal disc-derived wing morphogenesis; haltere morphogenesis; imaginal disc-derived leg morphogenesis. 64 alleles are reported. The phenotypes of these alleles are annotated with 63 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; thoracic segment; external compound sense organ; appendage segment; adult mesothoracic segment; embryonic segment; embryonic nervous system; organ system; antennal segment. It has 8 annotated transcripts and 8 annotated polypeptides.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> brain development ; GO:0007420 | inferred from mutant phenotype <newline> proximal/distal pattern formation ; GO:0009954 | traceable author statement <newline> specification of organ identity ; GO:0010092 | traceable author statement <newline> compound eye photoreceptor fate commitment ; GO:0001752 | inferred from mutant phenotype <newline> leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype <newline> specification of segmental identity, antennal segment ; GO:0007383 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype <newline> haltere morphogenesis ; GO:0048735 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> transcription factor activity ; GO:0003700 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356"]
[null,"FBgn0011224","hephaestus","heph","The gene hephaestus is referred to in FlyBase by the symbol Dmel\\heph (CG31000, FBgn0011224). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27676704..27819000. It has the cytological map location 100D3-100E1. There is experimental evidence that it has the molecular function</span>: mRNA 3'-UTR binding; translation repressor activity, nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: spermatid development; imaginal disc-derived wing margin morphogenesis; oocyte microtubule cytoskeleton polarization; imaginal disc-derived wing vein morphogenesis; Notch signaling pathway; negative regulation of oskar mRNA translation. 106 alleles are reported. The phenotypes of these alleles are annotated with: macrochaeta; testis; wing; individualization stage spermatid; spermatozoon. It has 22 annotated transcripts and 22 annotated polypeptides.","spermatid development ; GO:0007286 | inferred from mutant phenotype <newline> nuclear mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with NCBI_NP:002810 <newline> Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> negative regulation of oskar mRNA translation ; GO:0007319 | inferred from mutant phenotype <newline> oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay <newline> ribonucleoprotein complex ; GO:0030529 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR006536","poly-pyrimidine tract binding ; GO:0008187 | non-traceable author statement <newline> mRNA binding ; GO:0003729 | inferred from sequence or structural similarity <newline> poly-pyrimidine tract binding ; GO:0008187 | inferred from sequence or structural similarity with NCBI_NP:002810 <newline> mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay <newline> translation repressor activity, nucleic acid binding ; GO:0000900 | inferred from mutant phenotype <newline> nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR012677"]
[null,"FBgn0011236","ken and barbie","ken","The gene ken and barbie is referred to in FlyBase by the symbol Dmel\\ken (CG5575, FBgn0011236). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19757798..19764965. It has the cytological map location 60A6-60A7. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity; protein binding; nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: imaginal disc-derived female genitalia development; female analia development; male analia development; insemination; imaginal disc-derived male genitalia development; regulation of JAK-STAT cascade; phagocytosis, engulfment. 28 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; region of integument; adult; adult segment; antennal segment; embryonic/larval tracheal system; larval abdominal segment; female genitalia; spiracle; vulva; imaginal precursor; integumentary specialisation. It has one annotated transcript and one annotated polypeptide.","copulation ; GO:0007620 | non-traceable author statement <newline> insemination ; GO:0007320 | inferred from mutant phenotype <newline> female analia development ; GO:0045497 | inferred from mutant phenotype <newline> imaginal disc-derived female genitalia development ; GO:0007486 | inferred from mutant phenotype <newline> male analia development ; GO:0045496 | inferred from mutant phenotype <newline> imaginal disc-derived male genitalia development ; GO:0007485 | inferred from mutant phenotype <newline> regulation of JAK-STAT cascade ; GO:0046425 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with InterPro:IPR007087","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity <newline> nucleic acid binding ; GO:0003676 | inferred from sequence or structural similarity with InterPro:IPR007087 <newline> protein binding ; GO:0005515 | inferred from sequence or structural similarity with InterPro:IPR000210 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0011766","E2F transcription factor","E2f","The gene E2F transcription factor is referred to in FlyBase by the symbol Dmel\\E2f (CG6376, FBgn0011766). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17446026..17486127. It has the cytological map location 93E9-93F1. There is experimental evidence that it has the molecular function</span>: protein binding; RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of gene expression; cellular process; dendrite morphogenesis; neuron development; positive regulation of nurse cell apoptosis; muscle tissue development; antimicrobial humoral response; regulation of cell cycle; DNA endoreduplication. 70 alleles are reported. The phenotypes of these alleles are annotated with 31 unique terms, many of which group under: organ system; peripheral nervous system; nervous system; external compound sense organ; female germline cyst; egg; imaginal precursor; adult segment; cell part; primordium; adult mesothoracic segment. It has 3 annotated transcripts and 3 annotated polypeptides.","positive regulation of cell proliferation ; GO:0008284 | non-traceable author statement <newline> positive regulation of nurse cell apoptosis ; GO:0045850 | inferred from mutant phenotype <newline> DNA endoreduplication ; GO:0042023 | inferred from genetic interaction with CycE AND inferred from mutant phenotype <newline> eggshell chorion gene amplification ; GO:0007307 | traceable author statement <newline> G1/S transition of mitotic cell cycle ; GO:0000082 | traceable author statement <newline> imaginal disc development ; GO:0007444 | traceable author statement <newline> nurse cell apoptosis ; GO:0045476 | traceable author statement <newline> positive regulation of transcription ; GO:0045941 | traceable author statement <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> regulation of transcription involved in G1/S-phase of mitotic cell cycle ; GO:0000083 | non-traceable author statement <newline> growth ; GO:0040007 | non-traceable author statement <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | non-traceable author statement <newline> positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> muscle tissue development ; GO:0060537 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003316","nucleus ; GO:0005634 | inferred from direct assay <newline> Rb-E2F complex ; GO:0035189 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","DNA binding ; GO:0003677 | inferred from direct assay <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with Rbf <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription activator activity ; GO:0016563 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with dom inferred from physical interaction with l(3)mbt <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR003316"]
[null,"FBgn0011837","Tis11 homolog","Tis11","The gene Tis11 homolog is referred to in FlyBase by the symbol Dmel\\Tis11 (CG4070, FBgn0011837). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:12553395..12573736. It has the cytological map location 11B9-11B10. It is reported to have molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: RNA interference. 20 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","RNA interference ; GO:0016246 | inferred from mutant phenotype","nucleus ; GO:0005634 | non-traceable author statement","DNA binding ; GO:0003677 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000571 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000571"]
[null,"FBgn0015919","caupolican","caup","The gene caupolican is referred to in FlyBase by the symbol Dmel\\caup (CG10605, FBgn0015919). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:12603226..12614908. It has the cytological map location 69D1. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity, enhancer binding; transcription activator activity. There is experimental evidence that it is involved in the biological process</span>: imaginal disc-derived wing vein specification; compound eye morphogenesis; phagocytosis, engulfment. 13 alleles are reported. The phenotypes of these alleles are annotated with: mesothoracic segment; eye; macrochaeta; notopleural suture; vertical bristle; wing; microchaeta; ommatidium; scutellum. It has one annotated transcript and one annotated polypeptide.","equator specification ; GO:0045317 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from genetic interaction with ara <newline> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with ara","nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC_gene:PBX1; HGNC:8632; OMIM:176310","specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> transcription regulator activity ; GO:0030528 | non-traceable author statement <newline> RNA polymerase II transcription factor activity, enhancer binding ; GO:0003705 | inferred from sequence or structural similarity with ara <newline> transcription activator activity ; GO:0016563 | inferred from sequence or structural similarity with ara"]
[null,"FBgn0022720","Zinc finger protein 30C","zf30C","The gene Zinc finger protein 30C is referred to in FlyBase by the symbol Dmel\\zf30C (CG3998, FBgn0022720). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:9758338..9762377. It has the cytological map location 30C7. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: neuron development. 6 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; wing margin; posterior crossvein; wing; wing vein L2. It has one annotated transcript and one annotated polypeptide.","neuron development ; GO:0048666 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:U27186","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:U27186 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0023001","melted","melt","The gene melted is referred to in FlyBase by the symbol Dmel\\melt (CG8624, FBgn0023001). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:7127618..7136174. It has the cytological map location 65E4-65E5. There is experimental evidence that it has the molecular function</span>: specific transcriptional repressor activity; phosphoinositide binding; phosphatidylinositol-5-phosphate binding. There is experimental evidence that it is involved in the biological process</span>: insulin receptor signaling pathway; ectoderm development; sequestering of triglyceride; R8 cell fate specification; peripheral nervous system development. 17 alleles are reported. The phenotypes of these alleles are annotated with: photoreceptor cell R8 of yellow ommatidium; embryonic peripheral nervous system; embryonic nervous system; wing. It has 2 annotated transcripts and 2 annotated polypeptides.","sequestering of triglyceride ; GO:0030730 | inferred from mutant phenotype <newline> insulin receptor signaling pathway ; GO:0008286 | inferred from mutant phenotype <newline> ectoderm development ; GO:0007398 | inferred from expression pattern <newline> peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype <newline> R8 cell fate specification ; GO:0045464 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from direct assay","phosphoinositide binding ; GO:0035091 | inferred from direct assay <newline> phosphatidylinositol-5-phosphate binding ; GO:0010314 | inferred from direct assay <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype"]
[null,"FBgn0023215","Mnt","Mnt","The gene Mnt is referred to in FlyBase by the symbol Dmel\\Mnt (CG13316, FBgn0023215). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3565834..3594813. It has the cytological map location 3E4-3E5. There is experimental evidence that it has the molecular function</span>: protein binding; sequence-specific DNA binding; transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription; regulation of cell cycle; negative regulation of cell growth; phagocytosis, engulfment. 32 alleles are reported. The phenotypes of these alleles are annotated with: eye; adult head; ommatidium; wing hair. It has 7 annotated transcripts and 7 annotated polypeptides.","regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with dm <newline> regulation of transcription ; GO:0045449 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> negative regulation of cell growth ; GO:0030308 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity <newline> nucleus ; GO:0005634 | inferred by curator from GO:0003700 <newline> nucleus ; GO:0005634 | inferred from direct assay","RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with dm <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q99583 <newline> protein binding ; GO:0005515 | inferred from physical interaction with Max <newline> sequence-specific DNA binding ; GO:0043565 | inferred from direct assay <newline> transcription repressor activity ; GO:0016564 | inferred from direct assay"]
[null,"FBgn0024308","Smrter","Smr","The gene Smrter is referred to in FlyBase by the symbol Dmel\\Smr (CG4013, FBgn0024308). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:12580031..12636476. It has the cytological map location 11B10-11B14. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: regulation of mitotic cell cycle; phagocytosis, engulfment. 25 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","negative regulation of transcription, DNA-dependent ; GO:0045892 | traceable author statement <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype","polytene chromosome ; GO:0005700 | non-traceable author statement","transcription corepressor activity ; GO:0003714 | non-traceable author statement <newline> protein binding ; GO:0005515 | traceable author statement <newline> transcription corepressor activity ; GO:0003714 | traceable author statement <newline> transcription corepressor activity ; GO:0003714 | inferred from sequence or structural similarity with EMBL:AF125672; protein_id:AAD22973.1 <newline> protein binding ; GO:0005515 | inferred from physical interaction with Su(H) <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001005"]
[null,"FBgn0025463","Brahma associated protein 60kD","Bap60","The gene Brahma associated protein 60kD is referred to in FlyBase by the symbol Dmel\\Bap60 (CG4303, FBgn0025463). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:13051478..13053611. It has the cytological map location 11E1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis; neuron development; muscle organ development; positive regulation of transcription, DNA-dependent. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","positive regulation of transcription, DNA-dependent ; GO:0045893 | inferred from direct assay <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype","brahma complex ; GO:0035060 | inferred from direct assay <newline> chromatin remodeling complex ; GO:0016585 | inferred from sequence or structural similarity with EMBL:U66620","transcription coactivator activity ; GO:0003713 | contributes_to inferred by curator from GO:0035060 <newline> protein binding ; GO:0005515 | inferred from physical interaction with mor <newline> general RNA polymerase II transcription factor activity ; GO:0016251 | inferred from sequence or structural similarity with EMBL:U66620 <newline> protein binding ; GO:0005515 | inferred from physical interaction with Myo10A"]
[null,"FBgn0027339","jim","jim","The gene jim is referred to in FlyBase by the symbol Dmel\\jim (CG11352, FBgn0027339). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:22789077..22826488. It has the cytological map location 80A2-80A4. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. The biological processes in which it is involved are not known. 32 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","-","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:AB007407; protein_id:BAA25190","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:AB007407; protein_id:BAA25190 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0040283","SMC1","SMC1","The gene SMC1 is referred to in FlyBase by the symbol Dmel\\SMC1 (CG6057, FBgn0040283). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19884024..19888538. It has the cytological map location 95D11. Based on sequence similarity, it is predicted to have molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis; negative regulation of gene expression; neuron remodeling; mushroom body development. 6 alleles are reported. The phenotype of these alleles is annotated with: condensed chromosome. It has one annotated transcript and one annotated polypeptide.","sister chromatid cohesion ; GO:0007062 | inferred from sequence or structural similarity with SGD_LOCUS:SMC1; SGD:S0001886 <newline> sister chromatid cohesion ; GO:0007062 | non-traceable author statement <newline> negative regulation of gene expression ; GO:0010629 | inferred from genetic interaction with ct <newline> mushroom body development ; GO:0016319 | inferred from mutant phenotype <newline> neuron remodeling ; GO:0016322 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype","cohesin complex ; GO:0008278 | non-traceable author statement <newline> cohesin complex ; GO:0008278 | inferred from sequence or structural similarity with SGD_LOCUS:SMC1; SGD:S0001886 <newline> cohesin complex ; GO:0008278 | inferred from sequence or structural similarity <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> cohesin complex ; GO:0008278 | inferred from direct assay <newline> chromosome ; GO:0005694 | colocalizes_with inferred from direct assay <newline> transcriptionally active chromatin ; GO:0035327 | inferred from direct assay","DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:SMC1; SGD:S0001886 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003395, InterPro:IPR010935 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR010935"]
[null,"FBgn0085432","pangolin","pan","The gene pangolin is referred to in FlyBase by the symbol Dmel\\pan (CG34403, FBgn0085432). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:89956..129430. It has the cytological map location 102A3-102A4. There is experimental evidence that it has the molecular function</span>: specific transcriptional repressor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of Wnt receptor signaling pathway; spiracle morphogenesis, open tracheal system; embryonic pattern specification; regulation of hemocyte differentiation; imaginal disc-derived wing morphogenesis; positive regulation of transcription; salivary gland morphogenesis. 44 alleles are reported. The phenotypes of these alleles are annotated with 39 unique terms, many of which group under: organ system; adult segment; late extended germ band embryo; thoracic segment; muscle founder cell; peripheral nervous system; embryonic/larval tracheal system; adult mesothoracic segment; dorsal thoracic disc; spiracle. It has 10 annotated transcripts and 10 annotated polypeptides.","embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from sequence or structural similarity with MGD:Tcf7l2; MGI:MGI:1202879 <newline> segment polarity determination ; GO:0007367 | non-traceable author statement <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> mesodermal cell fate determination ; GO:0007500 | traceable author statement <newline> regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype <newline> spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | non-traceable author statement <newline> regulation of Wnt receptor signaling pathway ; GO:0030111 | inferred from mutant phenotype <newline> negative regulation of Wnt receptor signaling pathway ; GO:0030178 | non-traceable author statement <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> positive regulation of transcription ; GO:0045941 | inferred from mutant phenotype","transcription factor complex ; GO:0005667 | inferred from sequence or structural similarity with MGD:Tcf7l2; MGI:MGI:1202879 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000910"]
[null,"FBgn0259211","grainy head","grh","The gene grainy head is referred to in FlyBase by the symbol Dmel\\grh (CG42311, FBgn0259211). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13690294..13729118. It has the cytological map location 54E10-54F1. There is experimental evidence that it has the molecular function</span>: specific RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; nervous system development; tracheal outgrowth, open tracheal system; regulation of cell proliferation; open tracheal system development; regulation of tube length, open tracheal system; plasma membrane organization; chitin-based embryonic cuticle biosynthetic process. 70 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; embryonic/larval tracheal system; somatic stem cell; cephalopharyngeal skeleton; portion of tissue; cuticle; adult segment; larval abdominal segment; adult mesothoracic segment; developing anatomical structure. It has 7 annotated transcripts and 7 annotated polypeptides.","plasma membrane organization ; GO:0007009 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype <newline> tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from expression pattern <newline> ganglion mother cell fate determination ; GO:0007402 | traceable author statement <newline> ventral cord development ; GO:0007419 | non-traceable author statement <newline> nervous system development ; GO:0007399 | inferred from mutant phenotype <newline> regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype <newline> cellular membrane organization ; GO:0016044 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> primary branching, open tracheal system ; GO:0007428 | traceable author statement <newline> regulation of tube architecture, open tracheal system ; GO:0035152 | traceable author statement","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","DNA binding ; GO:0003677 | inferred from direct assay <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from direct assay <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement"]
[null,"FBgn0259986","nab","nab","The gene nab is referred to in FlyBase by the symbol Dmel\\nab (CG33545, FBgn0259986). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4153618..4160932. It has the cytological map location 64A8. There is experimental evidence that it has the molecular function</span>: transcription cofactor activity. There is experimental evidence that it is involved in the biological process</span>: locomotory behavior; neuron development; wing disc pattern formation. 18 alleles are reported. The phenotypes of these alleles are annotated with: tarsal segment 2; eye; tarsal segment 4; tarsal segment 3; ommatidium; wing hinge; EL neuron; pigment cell. It has 2 annotated transcripts and 2 annotated polypeptides.","locomotory behavior ; GO:0007626 | inferred from mutant phenotype <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:Q62722 <newline> wing disc pattern formation ; GO:0035222 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q62722","transcription cofactor activity ; GO:0003712 | inferred from mutant phenotype inferred from physical interaction with rn inferred from physical interaction with sqz inferred from genetic interaction with rn inferred from genetic interaction with sqz <newline> transcription factor binding ; GO:0008134 | inferred from sequence or structural similarity with EMBL:U47543 <newline> transcription repressor activity ; GO:0016564 | inferred from sequence or structural similarity with UniProtKB:Q62722"]
[null,"FBgn0261648","spalt major","salm","The gene spalt major is referred to in FlyBase by the symbol Dmel\\salm (CG6464, FBgn0261648). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:11434311..11445603. It has the cytological map location 32F1-32F2. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity; transcription regulator activity. There is experimental evidence that it is involved in the biological process</span>: oenocyte development; notum cell fate specification; R8 cell differentiation; sensory organ development; compound eye photoreceptor cell differentiation; spiracle morphogenesis, open tracheal system; R7 cell differentiation; open tracheal system development; antennal joint development. 28 alleles are reported. The phenotypes of these alleles are annotated with 52 unique terms, many of which group under: adult segment; adult mesothoracic segment; peripheral nervous system; organ system; nervous system; embryonic/larval tracheal system; embryonic nervous system; antennal segment; appendage segment; embryonic segment. It has one annotated transcript and one annotated polypeptide.","spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> negative regulation of transcription ; GO:0016481 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> oenocyte development ; GO:0007438 | inferred from mutant phenotype <newline> antennal joint development ; GO:0048098 | inferred from mutant phenotype <newline> R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype <newline> R8 cell differentiation ; GO:0045465 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | non-traceable author statement <newline> epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement <newline> R8 cell differentiation ; GO:0045465 | non-traceable author statement <newline> segment specification ; GO:0007379 | non-traceable author statement <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype <newline> notum cell fate specification ; GO:0035310 | inferred from mutant phenotype","nucleus ; GO:0005634 | non-traceable author statement <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> transcription regulator activity ; GO:0030528 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087"]
[null,"FBgn0024321","NK7.1","NK7.1","The gene NK7.1 is referred to in FlyBase by the symbol Dmel\\NK7.1 (CG8524, FBgn0024321). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: regulation of transcription, DNA-dependent. 11 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Homeobox; Homeobox, conserved site; Homeobox, eukaryotic; Homeodomain-like; Homeodomain-related. Gene sequence location is 3R:10155862..10198673.","regulation of transcription, DNA-dependent ; GO:0006355 | inferred from sequence or structural similarity with InterPro:IPR001356","nucleus ; GO:0005634 | inferred from sequence or structural similarity with InterPro:IPR001356","sequence-specific DNA binding transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with InterPro:IPR001356 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970 <newline> transcription regulator activity ; GO:0030528 | inferred from electronic annotation with InterPro:IPR017970"]
[null,"FBgn0000412","D1 chromosomal protein","D1","The gene D1 chromosomal protein is referred to in FlyBase by the symbol Dmel\\D1 (CG9745, FBgn0000412). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: satellite DNA binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: AT hook, DNA-binding motif; AT hook-like. Gene sequence location is 3R:5063805..5066376.","-","nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from direct assay","AT DNA binding ; GO:0003680 | non-traceable author statement <newline> double-stranded DNA binding ; GO:0003690 | non-traceable author statement <newline> satellite DNA binding ; GO:0003696 | non-traceable author statement <newline> satellite DNA binding ; GO:0003696 | inferred from direct assay"]
[null,"FBgn0038499","Brf","Brf","The gene Brf is referred to in FlyBase by the symbol Dmel\\Brf (CG31256, FBgn0038499). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: transcription factor binding. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription from RNA polymerase III promoter. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Brf1-like TBP-binding; Cyclin; Cyclin-like; Cyclin-related; Transcription factor TFIIB, cyclin-related; Transcription factor TFIIB-related; Zinc finger, TFIIB-type. Gene sequence location is 3R:13200555..13217054.","regulation of transcription from RNA polymerase III promoter ; GO:0006359 | inferred from direct assay AND inferred from physical interaction with Trf <newline> regulation of transcription from RNA polymerase III promoter ; GO:0006359 | inferred from sequence or structural similarity with UniProtKB:P46070 <newline> translational initiation ; GO:0006413 | inferred from electronic annotation with InterPro:IPR013150 <newline> transcription initiation, DNA-dependent ; GO:0006352 | inferred from electronic annotation with InterPro:IPR000812 <newline> positive regulation of transcription ; GO:0045941 | inferred from electronic annotation with InterPro:IPR011665","transcription factor complex ; GO:0005667 | inferred from physical interaction with Trf <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> transcription factor TFIIIB complex ; GO:0000126 | inferred from sequence or structural similarity with UniProtKB:P43072","transcription factor binding ; GO:0008134 | inferred from physical interaction with Trf <newline> RNA polymerase III transcription factor activity ; GO:0003709 | non-traceable author statement <newline> RNA polymerase III transcription factor activity ; GO:0003709 | inferred from sequence or structural similarity with UniProtKB:P43072 <newline> translation initiation factor activity ; GO:0003743 | inferred from electronic annotation with InterPro:IPR013150 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000812, InterPro:IPR011665, InterPro:IPR013137 <newline> transcription activator activity ; GO:0016563 | inferred from electronic annotation with InterPro:IPR011665"]
[null,"FBgn0259789","vielfaltig","vfl","The gene vielfaltig is referred to in FlyBase by the symbol Dmel\\vfl (CG12701, FBgn0259789). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding. There is experimental evidence that it is involved in the biological process</span>: mitotic cell cycle. 9 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; peripheral nervous system; anatomical structure; adult segment; embryonic nervous system; thoracic segment; integumentary plate; developing anatomical structure; cell part; embryonic neuron. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Zinc finger, C2H2-like; Zinc finger, C2H2-type; Zinc finger, C2H2-type/integrase, DNA-binding; Zinc finger, double-stranded RNA binding. Gene sequence location is X:19670020..19676961.","mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype","chromatin ; GO:0000785 | colocalizes_with inferred from direct assay <newline> nucleoplasm ; GO:0005654 | inferred from direct assay","sequence-specific DNA binding ; GO:0043565 | inferred from direct assay <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0037751","matotopetli","topi","The gene matotopetli is referred to in FlyBase by the symbol Dmel\\topi (CG8484, FBgn0037751). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: male meiosis; positive regulation of transcription, meiotic; spermatogenesis. 5 alleles are reported. The phenotypes of these alleles are annotated with: secondary spermatocyte; spermatid. It has one annotated transcript and one annotated polypeptide. Protein features are: Zinc finger, C2H2-like; Zinc finger, C2H2-type; Zinc finger, C2H2-type/integrase, DNA-binding. Gene sequence location is 3R:5600843..5603665.","male meiosis ; GO:0007140 | inferred from mutant phenotype <newline> spermatogenesis ; GO:0007283 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> positive regulation of transcription during meiosis ; GO:0051039 | inferred from mutant phenotype","nucleus ; GO:0005634 | non-traceable author statement <newline> nuclear chromatin ; GO:0000790 | inferred from direct assay","DNA binding ; GO:0003677 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087"]
[null,"FBgn0023180","Origin recognition complex subunit 6","Orc6","The gene Origin recognition complex subunit 6 is referred to in FlyBase by the symbol Dmel\\Orc6 (CG1584, FBgn0023180). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of GTPase activity; DNA-dependent DNA replication initiation; mitosis; DNA replication; M phase of mitotic cell cycle. 14 alleles are reported. The phenotypes of these alleles are annotated with: embryonic salivary gland; imaginal disc; embryonic/larval brain; larval optic lobe. It has one annotated transcript and one annotated polypeptide. Protein features are: Origin recognition complex, subunit 6; Origin recognition complex, subunit 6, metazoa/plant. Gene sequence location is 2R:5732964..5733964.","DNA-dependent DNA replication initiation ; GO:0006270 | inferred from sequence or structural similarity with EMBL:AF139659; protein_id:AAD32667.1 <newline> DNA-dependent DNA replication initiation ; GO:0006270 | inferred from direct assay <newline> DNA-dependent DNA replication ; GO:0006261 | non-traceable author statement <newline> chromatin silencing ; GO:0006342 | non-traceable author statement <newline> DNA replication ; GO:0006260 | inferred from direct assay <newline> mitosis ; GO:0007067 | inferred from mutant phenotype <newline> M phase of mitotic cell cycle ; GO:0000087 | inferred from mutant phenotype <newline> positive regulation of GTPase activity ; GO:0043547 | inferred from direct assay","nuclear origin of replication recognition complex ; GO:0005664 | inferred from sequence or structural similarity with EMBL:AF139659; protein_id:AAD32667.1 <newline> nuclear origin of replication recognition complex ; GO:0005664 | inferred from direct assay <newline> nuclear origin of replication recognition complex ; GO:0005664 | non-traceable author statement <newline> origin recognition complex ; GO:0000808 | inferred from direct assay <newline> plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay <newline> septin complex ; GO:0031105 | colocalizes_with inferred from direct assay","DNA binding ; GO:0003677 | non-traceable author statement <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR008721"]
[null,"FBgn0022764","Sin3A","Sin3A","The gene Sin3A is referred to in FlyBase by the symbol Dmel\\Sin3A (CG8815, FBgn0022764). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of transcription; dendrite morphogenesis; neuron development; regulation of mitotic cell cycle; muscle organ development; negative regulation of transcription, DNA-dependent. 59 alleles are reported. The phenotypes of these alleles are annotated with: embryonic heart; mitochondrion; crystal cell. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Histone deacetylase interacting; Paired amphipathic helix. Gene sequence location is 2R:8462745..8480397.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> negative regulation of transcription ; GO:0016481 | inferred from expression pattern <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with SGD_LOCUS:SIN3; SGD:S0005364 <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | traceable author statement <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype <newline> negative regulation of transcription ; GO:0016481 | inferred from direct assay","nucleus ; GO:0005634 | non-traceable author statement <newline> chromatin ; GO:0000785 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> Sin3 complex ; GO:0016580 | non-traceable author statement <newline> euchromatin ; GO:0000791 | traceable author statement <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD_LOCUS:SIN3; SGD:S0005364 <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> polytene chromosome ; GO:0005700 | inferred from direct assay","RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | inferred from mutant phenotype <newline> sequence-specific DNA binding transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with SGD_LOCUS:SIN3; SGD:S0005364 <newline> transcription cofactor activity ; GO:0003712 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | inferred from direct assay"]
[]
["Transcriptional/Translational Regulation"]
[null,"FBgn0034261","Hermansky-Pudlak Syndrome 4 ortholog","HPS4","The gene Hermansky-Pudlak Syndrome 4 ortholog is referred to in FlyBase by the symbol Dmel\\HPS4 (CG4966, FBgn0034261). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: odorant binding; thymidylate synthase (FAD) activity; FAD binding. There is experimental evidence that it is involved in the biological process</span>: miRNA loading onto RISC involved in gene silencing by miRNA; negative regulation of gene silencing by RNA; siRNA loading onto RISC involved in chromatin silencing by small RNA. 11 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Pheromone/general odorant binding protein, PBP/GOBP; Thymidylate synthase complementing protein ThyX. Gene sequence location is 2R:13571102..13578327.","negative regulation of gene silencing by RNA ; GO:0060967 | inferred from mutant phenotype <newline> miRNA loading onto RISC involved in gene silencing by miRNA ; GO:0035280 | inferred from mutant phenotype <newline> siRNA loading onto RISC involved in chromatin silencing by small RNA ; GO:0070923 | inferred from mutant phenotype <newline> transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR006170 <newline> dTMP biosynthetic process ; GO:0006231 | inferred from electronic annotation with InterPro:IPR003669","lysosomal membrane ; GO:0005765 | inferred from direct assay <newline> late endosome membrane ; GO:0031902 | inferred from direct assay","thymidylate synthase (FAD) activity ; GO:0050797 | inferred from electronic annotation with InterPro:IPR003669 <newline> flavin adenine dinucleotide binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR003669 <newline> odorant binding ; GO:0005549 | inferred from electronic annotation with InterPro:IPR006170"]
[null,"FBgn0035141","Cyclophilin-like","Cypl","The gene Cyclophilin-like is referred to in FlyBase by the symbol Dmel\\Cypl (CG13892, FBgn0035141). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: peptidyl-prolyl cis-trans isomerase activity. It is reported to be involved in the biological process</span>: regulation of post-mating oviposition; nuclear mRNA splicing, via spliceosome. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Cyclophilin-like; Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; Peptidyl-prolyl cis-trans isomerase, cyclophilin-type, conserved site. Gene sequence location is 3L:542122..542916.","regulation of post-mating oviposition ; GO:0048042 | non-traceable author statement <newline> nuclear mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011|GO:0071013 <newline> protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892","precatalytic spliceosome ; GO:0071011 | inferred from direct assay <newline> catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay","peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from sequence or structural similarity with UniProtKB:Q9DCY1"]
[null,"FBgn0036774","mitochondrial ribosomal protein S26","mRpS26","The gene mitochondrial ribosomal protein S26 is referred to in FlyBase by the symbol Dmel\\mRpS26 (CG7354, FBgn0036774). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of ribosome. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translation. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 3L:18099681..18100602.","translation ; GO:0006412 | inferred from sequence or structural similarity with protein_id:CAC20860","mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with protein_id:CAC20860","structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with protein_id:CAC20860"]
[null,"FBgn0005533","Ribosomal protein S17","RpS17","The gene Ribosomal protein S17 is referred to in FlyBase by the symbol Dmel\\RpS17 (CG3922, FBgn0005533). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of ribosome. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translation. 12 alleles are reported. The phenotype of these alleles is annotated with: macrochaeta. It has one annotated transcript and one annotated polypeptide. Protein features are: Ribosomal protein S17e; Ribosomal protein S17e, conserved site. Gene sequence location is 3L:9421789..9422917.","translation ; GO:0006412 | inferred from sequence or structural similarity with MGD:Rps17; MGI:MGI:1309526","ribosome ; GO:0005840 | non-traceable author statement <newline> lipid particle ; GO:0005811 | inferred from direct assay <newline> cytosolic small ribosomal subunit ; GO:0022627 | inferred from sequence or structural similarity with MGD:Rps17; MGI:MGI:1309526","structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with MGD:Rps17; MGI:MGI:1309526 <newline> structural constituent of ribosome ; GO:0003735 | non-traceable author statement"]
[null,"FBgn0019936","Ribosomal protein S20","RpS20","The gene Ribosomal protein S20 is referred to in FlyBase by the symbol Dmel\\RpS20 (CG15693, FBgn0019936). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of ribosome. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translation. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Ribosomal protein S10; Ribosomal protein S10, conserved site; Ribosomal protein S10, eukaryotic/archaeal. Gene sequence location is 3R:16647901..16649078.","translation ; GO:0006412 | non-traceable author statement <newline> translation ; GO:0006412 | inferred from sequence or structural similarity with SGD_LOCUS:RPS20; SGD:S0001007","ribosome ; GO:0005840 | non-traceable author statement <newline> lipid particle ; GO:0005811 | inferred from direct assay <newline> cytosolic small ribosomal subunit ; GO:0022627 | non-traceable author statement <newline> cytosolic small ribosomal subunit ; GO:0022627 | inferred from sequence or structural similarity with SGD_LOCUS:RPS20; SGD:S0001007","structural constituent of ribosome ; GO:0003735 | non-traceable author statement <newline> structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with SGD_LOCUS:RPS20; SGD:S0001007 <newline> RNA binding ; GO:0003723 | inferred from electronic annotation with InterPro:IPR018268"]
[null,"FBgn0022764","Sin3A","Sin3A","The gene Sin3A is referred to in FlyBase by the symbol Dmel\\Sin3A (CG8815, FBgn0022764). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of transcription; dendrite morphogenesis; neuron development; regulation of mitotic cell cycle; muscle organ development; negative regulation of transcription, DNA-dependent. 59 alleles are reported. The phenotypes of these alleles are annotated with: embryonic heart; mitochondrion; crystal cell. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Histone deacetylase interacting; Paired amphipathic helix. Gene sequence location is 2R:8462745..8480397.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> negative regulation of transcription ; GO:0016481 | inferred from expression pattern <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with SGD_LOCUS:SIN3; SGD:S0005364 <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | traceable author statement <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype <newline> negative regulation of transcription ; GO:0016481 | inferred from direct assay","nucleus ; GO:0005634 | non-traceable author statement <newline> chromatin ; GO:0000785 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> Sin3 complex ; GO:0016580 | non-traceable author statement <newline> euchromatin ; GO:0000791 | traceable author statement <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD_LOCUS:SIN3; SGD:S0005364 <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> polytene chromosome ; GO:0005700 | inferred from direct assay","RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | inferred from mutant phenotype <newline> sequence-specific DNA binding transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with SGD_LOCUS:SIN3; SGD:S0005364 <newline> transcription cofactor activity ; GO:0003712 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | inferred from direct assay"]
[null,"FBgn0011725","twin","twin","The gene twin is referred to in FlyBase by the symbol Dmel\\twin (CG31137, FBgn0011725). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: transcription regulator activity. There is experimental evidence that it is involved in the biological process</span>: oogenesis; nuclear-transcribed mRNA poly(A) tail shortening. 25 alleles are reported. The phenotypes of these alleles are annotated with: nurse cell ring canal; oocyte; egg chamber; nurse cell. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Endonuclease/exonuclease/phosphatase; Leucine-rich repeat; Leucine-rich repeat, typical subtype. Gene sequence location is 3R:20023310..20047687.","nuclear-transcribed mRNA poly(A) tail shortening ; GO:0000289 | inferred from mutant phenotype <newline> nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ; GO:0000288 | inferred from sequence or structural similarity with SGD_LOCUS:CCR4; SGD:S0000019 <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with SGD_LOCUS:CCR4; SGD:S0000019 <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay <newline> CCR4-NOT complex ; GO:0030014 | inferred from sequence or structural similarity with SGD_LOCUS:CCR4; SGD:S0000019 <newline> cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD_LOCUS:CCR4; SGD:S0000019","transcription regulator activity ; GO:0030528 | inferred from sequence or structural similarity with SGD_LOCUS:CCR4; SGD:S0000019"]
[null,"FBgn0035235","-","CG7879","This gene is referred to in FlyBase by the symbol Dmel\\CG7879 (FBgn0035235). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: regulation of alternative nuclear mRNA splicing, via spliceosome. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Nucleotide-binding, alpha-beta plait; RNA recognition motif domain. Gene sequence location is 3L:1559800..1568608.","regulation of alternative nuclear mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred by curator from GO:0000381","mRNA binding ; GO:0003729 | inferred from sequence or structural similarity <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 <newline> nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR012677"]
[null,"FBgn0001942","Eukaryotic initiation factor 4a","eIF-4a","The gene Eukaryotic initiation factor 4a is referred to in FlyBase by the symbol Dmel\\eIF-4a (CG9075, FBgn0001942). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: translation initiation factor activity; RNA helicase activity. There is experimental evidence that it is involved in the biological process</span>: germ-line stem cell maintenance; mitotic spindle elongation; response to DNA damage stimulus; mitosis; mitotic spindle organization; dorsal/ventral axis specification; oogenesis; female germ-line stem cell division; regulation of alternative nuclear mRNA splicing, via spliceosome. 66 alleles are reported. The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: anatomical structure; developing anatomical structure; organ system; cuticle; peripheral nervous system; nervous system; parasegment 9; dorsal thoracic disc; multi-cell-component structure; parasegment 14; parasegment 2; cephalopharyngeal skeleton; external compound sense organ; late extended germ band embryo. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: DEAD-like helicase, N-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Helicase, superfamily 1/2, ATP-binding domain; RNA helicase, ATP-dependent, DEAD-box, conserved site; RNA helicase, DEAD-box type, Q motif. Gene sequence location is 2L:5981759..5985572.","dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype <newline> translational initiation ; GO:0006413 | inferred from sequence or structural similarity with SGD_LOCUS:TIF1; SGD:S0001767 <newline> translational initiation ; GO:0006413 | non-traceable author statement <newline> imaginal disc growth ; GO:0007446 | traceable author statement <newline> instar larval development ; GO:0002168 | traceable author statement <newline> translational initiation ; GO:0006413 | inferred from sequence or structural similarity <newline> DNA unwinding involved in replication ; GO:0006268 | non-traceable author statement <newline> regulation of alternative nuclear mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype <newline> mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from genetic interaction with bam <newline> female germ-line stem cell division ; GO:0048132 | inferred from genetic interaction with bam inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype <newline> mitosis ; GO:0007067 | inferred from mutant phenotype","eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity with SGD_LOCUS:TIF1; SGD:S0001767 <newline> cytosol ; GO:0005829 | non-traceable author statement <newline> cytosol ; GO:0005829 | inferred from sequence or structural similarity <newline> eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity <newline> nucleus ; GO:0005634 | inferred by curator from GO:0000381 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity <newline> translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD_LOCUS:TIF1; SGD:S0001767 <newline> translation initiation factor activity ; GO:0003743 | non-traceable author statement <newline> RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity with SGD_LOCUS:TIF2; SGD:S0003674 <newline> translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity <newline> RNA cap binding ; GO:0000339 | non-traceable author statement <newline> mRNA binding ; GO:0003729 | non-traceable author statement <newline> single-stranded DNA-dependent ATP-dependent DNA helicase activity ; GO:0017116 | non-traceable author statement <newline> ATP-dependent helicase activity ; GO:0008026 | inferred from electronic annotation with InterPro:IPR000629, InterPro:IPR011545 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000629, InterPro:IPR001650, InterPro:IPR011545"]
[null,"FBgn0003277","RNA polymerase II 215kD subunit","RpII215","The gene RNA polymerase II 215kD subunit is referred to in FlyBase by the symbol Dmel\\RpII215 (CG1554, FBgn0003277). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: DNA-directed RNA polymerase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transcription from RNA polymerase II promoter. 173 alleles are reported. The phenotypes of these alleles are annotated with: haltere; capitellum. It has one annotated transcript and one annotated polypeptide. Protein features are: RNA polymerase II, heptapeptide repeat, eukaryotic; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 5; RNA polymerase Rpb1, domain 6; RNA polymerase Rpb1, domain 7; RNA polymerase, N-terminal; RNA polymerase, alpha subunit. Gene sequence location is X:11456806..11464355.","transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC_gene:POLR2A; HGNC:9187; OMIM:180660 AND inferred from sequence or structural similarity with SGD_LOCUS:RPO21; SGD:S0002299 AND inferred from sequence or structural similarity with WB:ama-1; WP:CE28300 <newline> transcription from RNA polymerase II promoter ; GO:0006366 | non-traceable author statement","DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC_gene:POLR2A; HGNC:9187; OMIM:180660 AND inferred from sequence or structural similarity with SGD_LOCUS:RPO21; SGD:S0002299 AND inferred from sequence or structural similarity with WB:ama-1; WP:CE28300 <newline> DNA-directed RNA polymerase II, core complex ; GO:0005665 | non-traceable author statement <newline> polytene chromosome puff ; GO:0005703 | inferred from direct assay","DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity with HGNC_gene:POLR2A; HGNC:9187; OMIM:180660 AND inferred from sequence or structural similarity with SGD_LOCUS:RPO21; SGD:S0002299 AND inferred from sequence or structural similarity with WB:ama-1; WP:CE28300 <newline> DNA-directed RNA polymerase activity ; GO:0003899 | non-traceable author statement <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000684, InterPro:IPR000722, InterPro:IPR006592, InterPro:IPR007066, InterPro:IPR007073, InterPro:IPR007075, InterPro:IPR007080, InterPro:IPR007081, InterPro:IPR007083"]
[null,"FBgn0030719","eIF5","eIF5","The gene eIF5 is referred to in FlyBase by the symbol Dmel\\eIF5 (CG9177, FBgn0030719). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: translation initiation factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translational initiation. 4 alleles are reported. No phenotypic data is available. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Armadillo-type fold; MIF4-like, type 1/2/3; Translation initiation factor IF2/IF5; Translation initiation factor IF2/IF5, N-terminal; eIF4-gamma/eIF5/eIF2-epsilon. Gene sequence location is X:15881194..15886023.","translational initiation ; GO:0006413 | inferred from sequence or structural similarity <newline> translational initiation ; GO:0006413 | inferred from sequence or structural similarity with UniProtKB:Q07205 <newline> translational initiation ; GO:0006413 | inferred from sequence or structural similarity with UniProtKB:P55010 <newline> RNA metabolic process ; GO:0016070 | inferred from electronic annotation with InterPro:IPR016021","cytosol ; GO:0005829 | inferred from sequence or structural similarity <newline> cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:Q07205 <newline> cytosol ; GO:0005829 | inferred from sequence or structural similarity with UniProtKB:P55010","translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity <newline> translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with UniProtKB:Q07205 <newline> translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with UniProtKB:P55010"]
[null,"FBgn0038872","Negative elongation factor A","Nelf-A","The gene Negative elongation factor A is referred to in FlyBase by the symbol Dmel\\Nelf-A (CG5874, FBgn0038872). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: negative regulation of transcription from RNA polymerase II promoter, mitotic. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 3R:17049426..17055234.","negative regulation of transcription from RNA polymerase II promoter during mitosis ; GO:0007070 | inferred from sequence or structural similarity with UniProtKB:P92204","transcriptional repressor complex ; GO:0017053 | inferred from sequence or structural similarity with UniProtKB:P92204","mRNA binding ; GO:0003729 | inferred from sequence or structural similarity with UniProtKB:P92204"]
[null,"FBgn0000352","costa","cos","The gene costa is referred to in FlyBase by the symbol Dmel\\cos (CG1708, FBgn0000352). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: smoothened binding; microtubule binding; protein binding; protein kinase binding; transcription factor binding. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; regulation of protein stability; negative regulation of transcription factor activity; imaginal disc-derived wing morphogenesis; cytoplasmic sequestering of transcription factor; negative regulation of transcription factor import into nucleus; positive regulation of hh target transcription factor activity. 88 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; thoracic segment; imaginal precursor; adult; dorsal thoracic disc; abdominal segment 10; vulva; epiproct. It has one annotated transcript and one annotated polypeptide. Protein features are: Kinesin, motor domain. Gene sequence location is 2R:3269669..3274617.","ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> positive regulation of hh target transcription factor activity ; GO:0007228 | inferred from mutant phenotype <newline> negative regulation of transcription factor import into nucleus ; GO:0042992 | inferred from mutant phenotype <newline> microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity <newline> regulation of proteolysis ; GO:0030162 | non-traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | inferred from physical interaction with smo <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | traceable author statement <newline> positive regulation of smoothened signaling pathway ; GO:0045880 | traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> regulation of protein stability ; GO:0031647 | inferred from direct assay <newline> negative regulation of transcription factor activity ; GO:0043433 | inferred from mutant phenotype <newline> cytoplasmic sequestering of transcription factor ; GO:0042994 | inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype <newline> microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR001752","cytoplasm ; GO:0005737 | inferred from direct assay <newline> kinesin complex ; GO:0005871 | inferred from sequence or structural similarity with Khc <newline> microtubule associated complex ; GO:0005875 | inferred from physical interaction with ci <newline> kinesin complex ; GO:0005871 | inferred from sequence or structural similarity with SGD_LOCUS:KIP3; SGD:S000003184 <newline> Hedgehog signaling complex ; GO:0035301 | inferred from physical interaction with ci AND inferred from physical interaction with fu <newline> kinesin complex ; GO:0005871 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> vesicle membrane ; GO:0012506 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | traceable author statement","microtubule binding ; GO:0008017 | inferred from direct assay <newline> motor activity ; GO:0003774 | inferred from sequence or structural similarity with Khc <newline> microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity <newline> smoothened binding ; GO:0005119 | inferred from physical interaction with smo <newline> protein binding ; GO:0005515 | inferred from physical interaction with fu <newline> protein kinase binding ; GO:0019901 | inferred from physical interaction with fu <newline> transcription factor binding ; GO:0008134 | inferred from physical interaction with ci <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752 <newline> microtubule motor activity ; GO:0003777 | inferred from electronic annotation with InterPro:IPR001752"]
[null,"FBgn0010774","Aly","Aly","The gene Aly is referred to in FlyBase by the symbol Dmel\\Aly (CG1101, FBgn0010774). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2903618..2906126. It has the cytological map location 84B2. Based on sequence similarity, it is predicted to have molecular function</span>: transcription coactivator activity; mRNA binding. It is reported to be involved in the biological process</span>: nuclear mRNA splicing, via spliceosome. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","nuclear mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011|GO:0071013","nucleoplasm ; GO:0005654 | inferred from direct assay <newline> nuclear membrane ; GO:0031965 | inferred from direct assay <newline> precatalytic spliceosome ; GO:0071011 | inferred from direct assay <newline> catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay","transcription coactivator activity ; GO:0003713 | inferred from sequence or structural similarity <newline> mRNA binding ; GO:0003729 | inferred from sequence or structural similarity <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 <newline> nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR012677"]
[null,"FBgn0026533","Dek","Dek","The gene Dek is referred to in FlyBase by the symbol Dmel\\Dek (CG5935, FBgn0026533). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12743726..12747861. It has the cytological map location 53D14. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: nucleic acid binding. It is reported to be involved in the biological process</span>: mRNA processing. 40 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides.","mRNA processing ; GO:0006397 | non-traceable author statement","nucleus ; GO:0005634 | non-traceable author statement","nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR003034"]
[null,"FBgn0034707","Mediator complex subunit 16","MED16","The gene Mediator complex subunit 16 is referred to in FlyBase by the symbol Dmel\\MED16 (CG5465, FBgn0034707). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18070651..18073397. It has the cytological map location 58C5-58C7. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription mediator activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transcription initiation from RNA polymerase II promoter; transcription from RNA polymerase II promoter. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity <newline> transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with NCBI_gi:4885647","nucleus ; GO:0005634 | inferred from sequence or structural similarity with NCBI_gi:4885647 <newline> mediator complex ; GO:0016592 | inferred from sequence or structural similarity <newline> mediator complex ; GO:0016592 | inferred from sequence or structural similarity with NCBI_gi:4885647","transcription cofactor activity ; GO:0003712 | non-traceable author statement <newline> RNA polymerase II transcription mediator activity ; GO:0016455 | inferred from sequence or structural similarity <newline> RNA polymerase II transcription mediator activity ; GO:0016455 | inferred from sequence or structural similarity with NCBI_gi:4885647"]
[]
["Hormonal regulation "]
[null,"FBgn0000567","Ecdysone-induced protein 74EF","Eip74EF","The gene Ecdysone-induced protein 74EF is referred to in FlyBase by the symbol Dmel\\Eip74EF (CG32180, FBgn0000567). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:17553258..17612407. It has the cytological map location 74D4-74E2. Based on sequence similarity, it is predicted to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: cellular process; autophagy; salivary gland cell autophagic cell death. 43 alleles are reported. The phenotypes of these alleles are annotated with: larva; salivary gland; adult epidermis; cuticle; air bubble; procephalic segment; anterior pupal spiracle. It has 4 annotated transcripts and 4 annotated polypeptides.","salivary gland cell autophagic cell death ; GO:0035071 | non-traceable author statement <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from mutant phenotype <newline> autophagy ; GO:0006914 | inferred from mutant phenotype <newline> cell death ; GO:0008219 | traceable author statement <newline> regulation of transcription ; GO:0045449 | non-traceable author statement <newline> regulation of development, heterochronic ; GO:0040034 | traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from sequence or structural similarity with UniProtKB:Q15725 <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | non-traceable author statement","nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGD:Elf1; MGI:MGI:107180 <newline> nucleus ; GO:0005634 | non-traceable author statement","transcription factor activity ; GO:0003700 | traceable author statement <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from sequence or structural similarity with UniProtKB:Q15725 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR000418 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000418"]
[null,"FBgn0000568","Ecdysone-induced protein 75B","Eip75B","The gene Ecdysone-induced protein 75B is referred to in FlyBase by the symbol Dmel\\Eip75B (CG8127, FBgn0000568). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:17945063..18052698. It has the cytological map location 75A10-75B6. There is experimental evidence that it has the molecular function</span>: heme binding. There is experimental evidence that it is involved in the biological process</span>: molting cycle, chitin-based cuticle; antimicrobial humoral response; ecdysis, chitin-based cuticle; regulation of ecdysteroid metabolic process. 136 alleles are reported. The phenotypes of these alleles are annotated with: eye; midgut chamber 3; midgut constriction 1; larval anterior spiracle; wing; mouth hooks. It has 4 annotated transcripts and 4 annotated polypeptides.","ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | non-traceable author statement <newline> ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype <newline> molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype <newline> regulation of ecdysteroid metabolic process ; GO:0007553 | inferred from mutant phenotype <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> molting cycle, chitin-based cuticle ; GO:0007591 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> oogenesis ; GO:0048477 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000324, InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR001723, InterPro:IPR003079, InterPro:IPR008946, InterPro:IPR013088","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:U09504 <newline> nucleus ; GO:0005634 | non-traceable author statement","ligand-dependent nuclear receptor activity ; GO:0004879 | inferred from sequence or structural similarity with EMBL:U09504 <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from sequence or structural similarity with EMBL:U09504 <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | non-traceable author statement <newline> heme binding ; GO:0020037 | inferred from direct assay <newline> steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR000536, InterPro:IPR008946 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR008946, InterPro:IPR013088"]
[null,"FBgn0003964","ultraspiracle","usp","The gene ultraspiracle is referred to in FlyBase by the symbol Dmel\\usp (CG4380, FBgn0003964). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1932831..1935343. It has the cytological map location 2C7. There is experimental evidence that it has the molecular function</span>: ecdysteroid hormone receptor activity; protein binding; lipid binding; protein heterodimerization activity; protein homodimerization activity. There is experimental evidence that it is involved in the biological process</span>: border follicle cell migration; dendrite morphogenesis; neuron development; neuron remodeling; muscle organ development. 22 alleles are reported. The phenotypes of these alleles are annotated with: dendrite; terminal filament; embryonic/larval anterior spiracle; midgut imaginal island; dorsal multidendritic neuron ddaC; imaginal disc. It has one annotated transcript and one annotated polypeptide.","neuron remodeling ; GO:0016322 | inferred from mutant phenotype <newline> ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | non-traceable author statement <newline> metamorphosis ; GO:0007552 | non-traceable author statement <newline> negative regulation of cell differentiation ; GO:0045596 | traceable author statement <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | traceable author statement <newline> regulation of development, heterochronic ; GO:0040034 | traceable author statement <newline> positive regulation of transcription ; GO:0045941 | traceable author statement <newline> dendrite morphogenesis ; GO:0048813 | non-traceable author statement <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000324, InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR001723, InterPro:IPR008946, InterPro:IPR013088","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P51128 <newline> ecdysone receptor holocomplex ; GO:0008230 | traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> polytene chromosome ; GO:0005700 | non-traceable author statement <newline> dendrite ; GO:0030425 | inferred from mutant phenotype","ecdysteroid hormone receptor activity ; GO:0004884 | inferred from direct assay <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | inferred from sequence or structural similarity with UniProtKB:P51128 <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with UniProtKB:P51128 <newline> protein binding ; GO:0005515 | inferred from physical interaction with rig <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> ecdysteroid hormone receptor activity ; GO:0004884 | non-traceable author statement <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | non-traceable author statement <newline> juvenile hormone binding ; GO:0005500 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with egg <newline> lipid binding ; GO:0008289 | inferred from direct assay <newline> protein homodimerization activity ; GO:0042803 | inferred from direct assay <newline> protein heterodimerization activity ; GO:0046982 | inferred from direct assay <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628"]
[null,"FBgn0004865","Ecdysone-induced protein 78C","Eip78C","The gene Ecdysone-induced protein 78C is referred to in FlyBase by the symbol Dmel\\Eip78C (CG18023, FBgn0004865). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:21220019..21257721. It has the cytological map location 78C2-78C3. Based on sequence similarity, it is predicted to have molecular function</span>: specific RNA polymerase II transcription factor activity; ligand-dependent nuclear receptor activity. It is reported to be involved in the biological process</span>: instar larval or pupal development. 39 alleles are reported. The phenotypes of these alleles are annotated with: eye; ommatidium; dorsal appendage. It has 3 annotated transcripts and 3 annotated polypeptides.","instar larval or pupal development ; GO:0002165 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000324, InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR001723, InterPro:IPR008946, InterPro:IPR013088","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q63503 <newline> nucleus ; GO:0005634 | non-traceable author statement","ligand-dependent nuclear receptor activity ; GO:0004879 | inferred from sequence or structural similarity with UniProtKB:Q63503 <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from sequence or structural similarity with UniProtKB:Q63503 <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | non-traceable author statement <newline> steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR000536, InterPro:IPR008946 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR008946, InterPro:IPR013088"]
[null,"FBgn0037770","Arginine methyltransferase 4","Art4","The gene Arginine methyltransferase 4 is referred to in FlyBase by the symbol Dmel\\Art4 (CG5358, FBgn0037770). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5808908..5811777. It has the cytological map location 85F4. There is experimental evidence that it has the molecular function</span>: protein-arginine omega-N asymmetric methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; histone methyltransferase activity. There is experimental evidence that it is involved in the biological process</span>: histone methylation; induction of programmed cell death by ecdysone; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine. 9 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","histone methylation ; GO:0016571 | inferred from direct assay <newline> induction of programmed cell death by ecdysone ; GO:0035078 | inferred from mutant phenotype <newline> peptidyl-arginine methylation, to asymmetrical-dimethyl arginine ; GO:0019919 | inferred from direct assay","histone methyltransferase complex ; GO:0035097 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay","histone methyltransferase activity ; GO:0042054 | inferred from direct assay <newline> histone-arginine N-methyltransferase activity ; GO:0008469 | inferred from sequence or structural similarity with MGD:Carm1; MGI:MGI:1913208 <newline> protein-arginine omega-N asymmetric methyltransferase activity ; GO:0035242 | inferred from direct assay <newline> protein-arginine omega-N monomethyltransferase activity ; GO:0035241 | inferred from direct assay <newline> protein-arginine N-methyltransferase activity ; GO:0016274 | inferred from sequence or structural similarity with UniProtKB:Q63009"]
[null,"FBgn0041092","taiman","tai","The gene taiman is referred to in FlyBase by the symbol Dmel\\tai (CG13109, FBgn0041092). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:9166802..9247187. It has the cytological map location 30A2-30A6. There is experimental evidence that it has the molecular function</span>: steroid hormone receptor binding; ligand-dependent nuclear receptor transcription coactivator activity. There is experimental evidence that it is involved in the biological process</span>: border follicle cell migration; axon extension involved in development. 57 alleles are reported. The phenotypes of these alleles are annotated with: border follicle cell; imaginal disc. It has 2 annotated transcripts and 2 annotated polypeptides.","border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with tgo <newline> axon extension involved in development ; GO:0048676 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000014","nucleus ; GO:0005634 | inferred from direct assay <newline> ecdysone receptor holocomplex ; GO:0008230 | colocalizes_with inferred from direct assay","transcription coactivator activity ; GO:0003713 | inferred from sequence or structural similarity <newline> transcription coactivator activity ; GO:0003713 | non-traceable author statement <newline> steroid hormone receptor binding ; GO:0035258 | inferred from physical interaction with EcR <newline> ligand-dependent nuclear receptor transcription coactivator activity ; GO:0030374 | inferred from direct assay <newline> signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR000014"]
[null,"FBgn0001257","Ecdysone-inducible gene L2","ImpL2","The gene Ecdysone-inducible gene L2 is referred to in FlyBase by the symbol Dmel\\ImpL2 (CG15009, FBgn0001257). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. It is reported to be involved in the biological process</span>: cell adhesion. 15 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Immunoglobulin I-set; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold. Gene sequence location is 3L:4224699..4236147.","cell adhesion ; GO:0007155 | traceable author statement","extracellular region ; GO:0005576 | non-traceable author statement","-"]
[]
["Metabolic/ Enzymatic function"]
[null,"FBgn0030049","-","Trf4-1","This gene is referred to in FlyBase by the symbol Dmel\\Trf4-1 (CG11265, FBgn0030049). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: polynucleotide adenylyltransferase activity. There is experimental evidence that it is involved in the biological process</span>: ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process. 12 alleles are reported. The phenotypes of these alleles are annotated with: eye; wing. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Nucleotidyl transferase domain; PAP/25A-associated. Gene sequence location is X:8454668..8461653.","sister chromatid cohesion ; GO:0007062 | non-traceable author statement <newline> ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process ; GO:0043630 | inferred from mutant phenotype","-","DNA-directed DNA polymerase activity ; GO:0003887 | non-traceable author statement <newline> DNA topoisomerase activity ; GO:0003916 | inferred from sequence or structural similarity with EMBL:AF089896; protein_id:AAD45198.1 <newline> polynucleotide adenylyltransferase activity ; GO:0004652 | inferred from direct assay"]
[null,"FBgn0003071","Phosphofructokinase","Pfk","The gene Phosphofructokinase is referred to in FlyBase by the symbol Dmel\\Pfk (CG4001, FBgn0003071). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: 6-phosphofructokinase activity. There is experimental evidence that it is involved in the biological process</span>: glycolysis. 10 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: 6-phosphofructokinase, eukaryotic type; Phosphofructokinase; Phosphofructokinase domain; Phosphofructokinase, conserved site. Gene sequence location is 2R:5997245..6004962.","glycolysis ; GO:0006096 | non-traceable author statement <newline> glycolysis ; GO:0006096 | inferred from mutant phenotype","6-phosphofructokinase complex ; GO:0005945 | inferred by curator from GO:0003872 <newline> 6-phosphofructokinase complex ; GO:0005945 | inferred from electronic annotation with InterPro:IPR000023, InterPro:IPR015912","6-phosphofructokinase activity ; GO:0003872 | inferred from sequence or structural similarity with UniProtKB:Q27778 <newline> 6-phosphofructokinase activity ; GO:0003872 | inferred from mutant phenotype"]
[null,"FBgn0040070","thioredoxin-2","Trx-2","The gene thioredoxin-2 is referred to in FlyBase by the symbol Dmel\\Trx-2 (CG31884, FBgn0040070). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: disulfide oxidoreductase activity. There is experimental evidence that it is involved in the biological process</span>: cell redox homeostasis; determination of adult lifespan; response to DNA damage stimulus; response to oxidative stress. 17 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Thioredoxin; Thioredoxin domain; Thioredoxin fold; Thioredoxin, conserved site; Thioredoxin-like; Thioredoxin-like fold. Gene sequence location is 2L:9613165..9616048.","cell redox homeostasis ; GO:0045454 | inferred from direct assay <newline> determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> response to oxidative stress ; GO:0006979 | inferred from mutant phenotype <newline> response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype <newline> glycerol ether metabolic process ; GO:0006662 | inferred from electronic annotation with InterPro:IPR005746","nucleus ; GO:0005634 | inferred from direct assay","disulfide oxidoreductase activity ; GO:0015036 | non-traceable author statement <newline> disulfide oxidoreductase activity ; GO:0015036 | inferred from direct assay <newline> disulfide oxidoreductase activity ; GO:0015036 | inferred from sequence or structural similarity with SGD_LOCUS:TRX1; SGD:S0004033 <newline> electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR005746 <newline> protein disulfide oxidoreductase activity ; GO:0015035 | inferred from electronic annotation with InterPro:IPR005746"]
[null,"FBgn0041630","Hexosaminidase 1","Hexo1","The gene Hexosaminidase 1 is referred to in FlyBase by the symbol Dmel\\Hexo1 (CG1318, FBgn0041630). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: beta-N-acetylglucosaminidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: carbohydrate metabolic process. 5 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Acetylhexosaminidase, subunit a/b; Glycoside hydrolase, catalytic core; Glycoside hydrolase, family 20; Glycoside hydrolase, family 20, catalytic core; Glycoside hydrolase, subgroup, catalytic core. Gene sequence location is 3L:4288642..4291211.","carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR001540, InterPro:IPR013781, InterPro:IPR015882","plasma membrane ; GO:0005886 | inferred from direct assay","beta-N-acetylhexosaminidase activity ; GO:0004563 | inferred from sequence or structural similarity with UniProtKB:P49010 <newline> beta-N-acetylglucosaminidase activity ; GO:0016231 | inferred from direct assay <newline> cation binding ; GO:0043169 | inferred from electronic annotation with InterPro:IPR013781"]
[null,"FBgn0001229","Heat shock gene 67Bc","Hsp67Bc","The gene Heat shock gene 67Bc is referred to in FlyBase by the symbol Dmel\\Hsp67Bc (CG4190, FBgn0001229). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: protein amino acid lipidation; regulation of translational initiation by eIF2 alpha phosphorylation; regulation of autophagy. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Alpha crystallin/Heat shock protein; HSP20-like chaperone; Heat shock protein Hsp20. Gene sequence location is 3L:9364611..9365583.","response to heat ; GO:0009408 | inferred from sequence or structural similarity with EMBL:U96099 <newline> response to heat ; GO:0009408 | non-traceable author statement <newline> protein lipidation ; GO:0006497 | inferred from mutant phenotype <newline> regulation of autophagy ; GO:0010506 | inferred from mutant phenotype <newline> regulation of translational initiation by eIF2 alpha phosphorylation ; GO:0010998 | inferred from mutant phenotype","-","-"]
[null,"FBgn0001228","Heat shock gene 67Bb","Hsp67Bb","The gene Heat shock gene 67Bb is referred to in FlyBase by the symbol Dmel\\Hsp67Bb (CG4456, FBgn0001228). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. It is reported to be involved in the biological process</span>: response to heat. 3 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Rhodanese-like. Gene sequence location is 3L:9365822..9368064.","response to heat ; GO:0009408 | non-traceable author statement","-","-"]
[null,"FBgn0039580","Glutamine:fructose-6-phosphate aminotransferase 2","Gfat2","The gene Glutamine:fructose-6-phosphate aminotransferase 2 is referred to in FlyBase by the symbol Dmel\\Gfat2 (CG1345, FBgn0039580). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: glutamine-fructose-6-phosphate transaminase (isomerizing) activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: carbohydrate biosynthetic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Glucosamine-fructose-6-phosphate aminotransferase, isomerising; Glutamine amidotransferase, class-II; Glutamine amidotransferase, type II; Sugar isomerase (SIS). Gene sequence location is 3R:24162741..24165490.","carbohydrate biosynthetic process ; GO:0016051 | inferred from electronic annotation with InterPro:IPR005855","cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR005855","glutamine-fructose-6-phosphate transaminase (isomerizing) activity ; GO:0004360 | inferred from sequence or structural similarity with SGD_LOCUS:GFA1; SGD:S0001587 <newline> sugar binding ; GO:0005529 | inferred from electronic annotation with InterPro:IPR001347"]
[null,"FBgn0033466","Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase 1","Pal1","The gene Peptidyl-Î±-hydroxyglycine-Î±-amidating lyase 1 is referred to in FlyBase by the symbol Dmel\\Pal1 (CG12130, FBgn0033466). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: peptidylamidoglycolate lyase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction; peptide metabolic process. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: NHL repeat; NHL repeat, subgroup; Peptidyl-glycine alpha-amidating monooxygenase; Six-bladed beta-propeller, TolB-like. Gene sequence location is 2R:5847054..5851358.","oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000720 <newline> peptide metabolic process ; GO:0006518 | inferred from electronic annotation with InterPro:IPR000720","neuronal cell body ; GO:0043025 | inferred from direct assay <newline> membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR000720","peptidylglycine monooxygenase activity ; GO:0004504 | inferred from sequence or structural similarity with MGD:Pam; MGI:MGI:97475 <newline> peptidylamidoglycolate lyase activity ; GO:0004598 | inferred from direct assay <newline> copper ion binding ; GO:0005507 | inferred from electronic annotation with InterPro:IPR000720"]
[null,"FBgn0024806","DISCO Interacting Protein 2","DIP2","The gene DISCO Interacting Protein 2 is referred to in FlyBase by the symbol Dmel\\DIP2 (CG7020, FBgn0024806). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: protein binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: AMP-dependent synthetase/ligase; DMAP1-binding. Gene sequence location is 3L:250229..257974.","metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873","nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR010506","protein binding ; GO:0005515 | inferred from physical interaction with disco <newline> catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000873 <newline> transcription factor binding ; GO:0008134 | inferred from electronic annotation with InterPro:IPR010506"]
[null,"FBgn0004509","Furin 1","Fur1","The gene Furin 1 is referred to in FlyBase by the symbol Dmel\\Fur1 (CG10772, FBgn0004509). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21173090..21298778. It has the cytological map location 96D2-96E1. There is experimental evidence that it has the molecular function</span>: serine-type endopeptidase activity. It is reported to be involved in the biological process</span>: proteolysis. 27 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides.","proteolysis ; GO:0006508 | non-traceable author statement <newline> proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR000209, InterPro:IPR002884","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | inferred from direct assay AND inferred from sequence or structural similarity with HGNC_gene:FURIN; HGNC:8568; OMIM:136950 AND inferred from sequence or structural similarity with SGD_LOCUS:KEX2; SGD:S0005182 <newline> plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with Fur2 <newline> integral to Golgi membrane ; GO:0030173 | non-traceable author statement <newline> Golgi stack ; GO:0005795 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | non-traceable author statement","serine-type endopeptidase activity ; GO:0004252 | inferred from direct assay <newline> serine-type endopeptidase activity ; GO:0004252 | non-traceable author statement"]
[null,"FBgn0010548","Aldehyde dehydrogenase type III","Aldh-III","The gene Aldehyde dehydrogenase type III is referred to in FlyBase by the symbol Dmel\\Aldh-III (CG11140, FBgn0010548). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3354384..3364667. It has the cytological map location 43C4. Based on sequence similarity, it is predicted to have molecular function</span>: oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction; cellular aldehyde metabolic process. 12 alleles are reported. The phenotype of these alleles is annotated with: crystal cell. It has 8 annotated transcripts and 8 annotated polypeptides.","oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR012394, InterPro:IPR015590, InterPro:IPR016160, InterPro:IPR016161, InterPro:IPR016162 <newline> cellular aldehyde metabolic process ; GO:0006081 | inferred from electronic annotation with InterPro:IPR012394","lipid particle ; GO:0005811 | inferred from direct assay","oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor ; GO:0016620 | inferred from sequence or structural similarity with MGD:Aldh3a1; MGI:MGI:1353451 <newline> aldehyde dehydrogenase [NAD(P)+] activity ; GO:0004030 | inferred from electronic annotation with InterPro:IPR012394"]
[null,"FBgn0024289","Sorbitol dehydrogenase 1","Sodh-1","The gene Sorbitol dehydrogenase 1 is referred to in FlyBase by the symbol Dmel\\Sodh-1 (CG1982, FBgn0024289). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2878057..2880264. It has the cytological map location 84B2. It is reported to have molecular function</span>: L-iditol 2-dehydrogenase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002085, InterPro:IPR002328, InterPro:IPR013149","-","L-iditol 2-dehydrogenase activity ; GO:0003939 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002085, InterPro:IPR002328, InterPro:IPR013149 <newline> oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002085, InterPro:IPR002328, InterPro:IPR013149, InterPro:IPR013154"]
[null,"FBgn0028685","Rpt4","Rpt4","The gene Rpt4 is referred to in FlyBase by the symbol Dmel\\Rpt4 (CG3455, FBgn0028685). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: proteolysis. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: 26S proteasome subunit P45; ATPase, AAA+ type, core; ATPase, AAA-type, conserved site; ATPase, AAA-type, core. Gene sequence location is X:6183503..6185276.","proteolysis ; GO:0006508 | inferred from direct assay AND inferred from sequence or structural similarity with HGNC_gene:PSMC6; HGNC:9553; OMIM:602708 AND inferred from sequence or structural similarity with SGD_LOCUS:RPT4; SGD:S0005785 <newline> protein catabolic process ; GO:0030163 | inferred from electronic annotation with InterPro:IPR005937","proteasome regulatory particle, base subcomplex ; GO:0008540 | non-traceable author statement <newline> proteasome regulatory particle ; GO:0005838 | inferred from direct assay AND inferred from sequence or structural similarity with HGNC_gene:PSMC6; HGNC:9553; OMIM:602708 <newline> proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD_LOCUS:RPT4; SGD:S0005785 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR005937","ATPase activity ; GO:0016887 | inferred from sequence or structural similarity with SGD_LOCUS:RPT4; SGD:S0005785 <newline> endopeptidase activity ; GO:0004175 | inferred from direct assay <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960"]
[null,"FBgn0032135","GlcAT-S","GlcAT-S","The gene GlcAT-S is referred to in FlyBase by the symbol Dmel\\GlcAT-S (CG3881, FBgn0032135). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:9616469..9623109. It has the cytological map location 30C1. There is experimental evidence that it has the molecular function</span>: asioloorosomucoid beta-1,3-glucuronosyltransferase activity; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity; galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity; N-acetyllactosamine beta-1,3-glucuronosyltransferase activity. It is reported to be involved in the biological process</span>: glycosphingolipid biosynthetic process; glycoprotein biosynthetic process; proteoglycan biosynthetic process. 13 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","glycoprotein biosynthetic process ; GO:0009101 | non-traceable author statement <newline> glycosphingolipid biosynthetic process ; GO:0006688 | non-traceable author statement <newline> proteoglycan biosynthetic process ; GO:0030166 | non-traceable author statement","membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR005027","galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity ; GO:0015018 | non-traceable author statement <newline> N-acetyllactosamine beta-1,3-glucuronosyltransferase activity ; GO:0046987 | inferred from direct assay <newline> asioloorosomucoid beta-1,3-glucuronosyltransferase activity ; GO:0046988 | inferred from direct assay <newline> galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity ; GO:0046989 | inferred from direct assay <newline> galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity ; GO:0015018 | inferred from direct assay <newline> glucuronosyltransferase activity ; GO:0015020 | inferred from sequence or structural similarity with EMBL:AB010441; protein_id:BAA75219.1"]
[null,"FBgn0086768","Protein-L-isoaspartate (D-aspartate) O-methyltransferase","Pcmt","The gene Protein-L-isoaspartate (D-aspartate) O-methyltransferase is referred to in FlyBase by the symbol Dmel\\Pcmt (CG2152, FBgn0086768). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1378545..1380033. It has the cytological map location 101F-83B1. There is experimental evidence that it has the molecular function</span>: protein-L-isoaspartate (D-aspartate) O-methyltransferase activity. It is reported to be involved in the biological process</span>: protein repair; protein modification process. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","protein repair ; GO:0030091 | non-traceable author statement <newline> protein modification process ; GO:0006464 | non-traceable author statement <newline> protein modification process ; GO:0006464 | inferred from electronic annotation with InterPro:IPR000682","cytoplasm ; GO:0005737 | non-traceable author statement","protein-L-isoaspartate (D-aspartate) O-methyltransferase activity ; GO:0004719 | non-traceable author statement <newline> protein-L-isoaspartate (D-aspartate) O-methyltransferase activity ; GO:0004719 | inferred from sequence or structural similarity with MGD:Pcmt1; MGI:MGI:97502 <newline> protein-L-isoaspartate (D-aspartate) O-methyltransferase activity ; GO:0004719 | inferred from direct assay"]

{"sheet":"Sheet3- Cellular Function","index":2,"n_rows":163,"n_cols":9,"rows_kept":163,"merged":[[1,3,1,5]],"flags":["formulas_cached_only"]}
[]
[{"$nulls":3},"Classification based on cellular Function"]
[]
["Category","Flybase ID","NAME","SYMBOL","Summary of gene function from Flybase","GO_BIOLOGICAL_PROCESS","GO_CELLULAR_COMPONENT","GO_MOLECULAR_FUNCTION"]
[]
["Cell Cycle/DNA repair/Replication"]
[null,"FBgn0001323","knirps-like","knrl","The gene knirps-like is referred to in FlyBase by the symbol Dmel\\knrl (CG4761, FBgn0001323). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20590241..20613636. It has the cytological map location 77D4-77E1. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity; ligand-dependent nuclear receptor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of mitosis. 6 alleles are reported. The phenotypes of these alleles are annotated with: dorsal closure embryo; metathoracic femur; embryonic dorsal epidermis. It has one annotated transcript and one annotated polypeptide.","regulation of mitosis ; GO:0007088 | inferred from mutant phenotype <newline> epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> regulation of tube size, open tracheal system ; GO:0035151 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000324, InterPro:IPR001628, InterPro:IPR013088","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q60674 <newline> nucleus ; GO:0005634 | non-traceable author statement","ligand-dependent nuclear receptor activity ; GO:0004879 | inferred from sequence or structural similarity with UniProtKB:Q60674 <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with UniProtKB:Q60674 <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628"]
[null,"FBgn0002899","mutagen-sensitive 301","mus301","The gene mutagen-sensitive 301 is referred to in FlyBase by the symbol Dmel\\mus301 (CG7972, FBgn0002899). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:8130914..8135114. It has the cytological map location 66B8. Based on sequence similarity, it is predicted to have molecular function</span>: helicase activity. There is experimental evidence that it is involved in the biological process</span>: female meiosis chromosome segregation; germarium-derived oocyte fate determination; polarity specification of dorsal/ventral axis; intracellular mRNA localization; oogenesis; polarity specification of anterior/posterior axis; karyosome formation. 21 alleles are reported. The phenotypes of these alleles are annotated with: germline cyst; oocyte; karyosome; egg chamber; oocyte nucleus; dorsal appendage; nurse cell; synaptonemal complex. It has one annotated transcript and one annotated polypeptide.","intracellular mRNA localization ; GO:0008298 | inferred from mutant phenotype <newline> karyosome formation ; GO:0030717 | inferred from mutant phenotype <newline> germarium-derived oocyte fate determination ; GO:0007294 | inferred from genetic interaction with spn-A <newline> polarity specification of anterior/posterior axis ; GO:0009949 | inferred from mutant phenotype <newline> polarity specification of dorsal/ventral axis ; GO:0009951 | inferred from mutant phenotype <newline> oocyte differentiation ; GO:0009994 | non-traceable author statement <newline> intracellular mRNA localization ; GO:0008298 | traceable author statement <newline> female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype <newline> germarium-derived oocyte fate determination ; GO:0007294 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from genetic interaction with fs(1)K10 <newline> oogenesis ; GO:0048477 | traceable author statement <newline> regulation of translation ; GO:0006417 | traceable author statement","small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with EMBL:Z70200; protein_id:CAA94089 <newline> U5 snRNP ; GO:0005682 | inferred from sequence or structural similarity with EMBL:Z70200; protein_id:CAA94089","helicase activity ; GO:0004386 | inferred from sequence or structural similarity <newline> ATP-dependent helicase activity ; GO:0008026 | inferred from electronic annotation with InterPro:IPR011545 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001650, InterPro:IPR011545 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001650, InterPro:IPR011545"]
[null,"FBgn0002901","mutagen-sensitive 304","mus304","The gene mutagen-sensitive 304 is referred to in FlyBase by the symbol Dmel\\mus304 (CG7347, FBgn0002901). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:18102929..18105947. It has the cytological map location 75B9-75B10. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent DNA helicase activity. There is experimental evidence that it is involved in the biological process</span>: female meiosis chromosome segregation; reciprocal meiotic recombination; female meiosis; DNA repair; telomere maintenance; regulation of syncytial blastoderm mitotic cell cycle; DNA damage checkpoint. 15 alleles are reported. The phenotypes of these alleles are annotated with: cycle 13 embryo; dorsal mesothoracic disc; mitotic cell cycle; macrochaeta; cycle 12 embryo; cycle 14 embryo. It has one annotated transcript and one annotated polypeptide.","telomere maintenance ; GO:0000723 | inferred from genetic interaction with tefu <newline> DNA damage checkpoint ; GO:0000077 | inferred from mutant phenotype <newline> DNA repair ; GO:0006281 | inferred from mutant phenotype <newline> female meiosis ; GO:0007143 | inferred from mutant phenotype <newline> female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype <newline> reciprocal meiotic recombination ; GO:0007131 | inferred from mutant phenotype <newline> regulation of syncytial blastoderm mitotic cell cycle ; GO:0007348 | inferred from mutant phenotype <newline> response to DNA damage stimulus ; GO:0006974 | non-traceable author statement <newline> imaginal disc development ; GO:0007444 | traceable author statement <newline> mitotic cell cycle checkpoint ; GO:0007093 | traceable author statement <newline> response to radiation ; GO:0009314 | traceable author statement <newline> cell cycle checkpoint ; GO:0000075 | traceable author statement","cytoplasm ; GO:0005737 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | traceable author statement","ATP-dependent DNA helicase activity ; GO:0004003 | inferred from sequence or structural similarity"]
[null,"FBgn0003162","Punch","Pu","The gene Punch is referred to in FlyBase by the symbol Dmel\\Pu (CG9441, FBgn0003162). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:17062822..17070121. It has the cytological map location 57C7-57C8. There is experimental evidence that it has the molecular function</span>: GTP cyclohydrolase activity; GTP cyclohydrolase I activity. There is experimental evidence that it is involved in the biological process</span>: preblastoderm mitotic cell cycle; cuticle pigmentation; pteridine biosynthetic process; embryonic pattern specification; compound eye pigmentation; larval chitin-based cuticle development. 80 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; cuticle; adult segment; extended germ band embryo; peripheral nervous system; anatomical structure; adult mesothoracic segment; nervous system; integumentary system; blastoderm embryo; acellular anatomical structure; thoracic segment; cephalopharyngeal skeleton; external compound sense organ. It has 3 annotated transcripts and 3 annotated polypeptides.","tetrahydrobiopterin biosynthetic process ; GO:0006729 | non-traceable author statement <newline> compound eye pigmentation ; GO:0048072 | inferred from mutant phenotype <newline> pteridine biosynthetic process ; GO:0006728 | inferred from mutant phenotype <newline> preblastoderm mitotic cell cycle ; GO:0035185 | inferred from mutant phenotype <newline> larval chitin-based cuticle development ; GO:0008363 | inferred from mutant phenotype <newline> cuticle pigmentation ; GO:0048067 | inferred from mutant phenotype <newline> embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype <newline> tetrahydrofolate biosynthetic process ; GO:0046654 | inferred from electronic annotation with InterPro:IPR001474, InterPro:IPR018234","cytoplasm ; GO:0005737 | inferred from direct assay","GTP cyclohydrolase I activity ; GO:0003934 | inferred from sequence or structural similarity with UniProtKB:P22288 <newline> GTP cyclohydrolase I activity ; GO:0003934 | non-traceable author statement <newline> GTP cyclohydrolase activity ; GO:0003933 | inferred from direct assay <newline> GTP cyclohydrolase I activity ; GO:0003934 | inferred from direct assay"]
[null,"FBgn0003326","scabrous","sca","The gene scabrous is referred to in FlyBase by the symbol Dmel\\sca (CG17579, FBgn0003326). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8668049..8689515. It has the cytological map location 49C3-49D3. It is reported to have molecular function</span>: signal transducer activity. There is experimental evidence that it is involved in the biological process</span>: female meiosis chromosome segregation; compound eye development; imaginal disc-derived wing margin morphogenesis; nervous system development; ommatidial rotation; bristle morphogenesis. 71 alleles are reported. The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: peripheral nervous system; nervous system; adult segment; external compound sense organ; organ system; adult mesothoracic segment; plasma membrane part; plasma membrane; eo support cell; acrostichal bristle; imaginal precursor; adult cuticle; antennal segment. It has 2 annotated transcripts and 2 annotated polypeptides.","bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | inferred from genetic interaction with N <newline> female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype <newline> ommatidial rotation ; GO:0016318 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> lateral inhibition ; GO:0046331 | non-traceable author statement <newline> regulation of R8 cell spacing in compound eye ; GO:0045468 | traceable author statement <newline> regulation of R8 cell spacing in compound eye ; GO:0045468 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from genetic interaction with hh AND inferred from mutant phenotype <newline> R8 cell fate commitment ; GO:0007460 | traceable author statement <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002181, InterPro:IPR014716","fibrinogen complex ; GO:0005577 | inferred from sequence or structural similarity with NCBI_gi:4758348 <newline> extracellular region ; GO:0005576 | non-traceable author statement","signal transducer activity ; GO:0004871 | traceable author statement <newline> receptor binding ; GO:0005102 | inferred from electronic annotation with InterPro:IPR002181, InterPro:IPR014716"]
[null,"FBgn0003525","string","stg","The gene string is referred to in FlyBase by the symbol Dmel\\stg (CG1395, FBgn0003525). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25077540..25081502. It has the cytological map location 99A5. There is experimental evidence that it has the molecular function</span>: protein tyrosine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: protein amino acid dephosphorylation; cellular process; regulation of mitotic cell cycle; gastrulation; centriole replication; cell cycle; G2/M transition of mitotic cell cycle. 128 alleles are reported. The phenotypes of these alleles are annotated with 49 unique terms, many of which group under: peripheral nervous system; nervous system; organ system; adult segment; embryonic nervous system; imaginal precursor; external compound sense organ; adult mesothoracic segment; nuclear part; embryonic neuron; cell cycle. It has one annotated transcript and one annotated polypeptide.","G2/M transition of mitotic cell cycle ; GO:0000086 | inferred from sequence or structural similarity <newline> G2/M transition of mitotic cell cycle ; GO:0000086 | inferred from mutant phenotype <newline> protein amino acid dephosphorylation ; GO:0006470 | inferred from direct assay <newline> centriole replication ; GO:0007099 | inferred from mutant phenotype <newline> protein amino acid dephosphorylation ; GO:0006470 | non-traceable author statement <newline> cell cycle ; GO:0007049 | inferred from mutant phenotype <newline> gastrulation ; GO:0007369 | non-traceable author statement <newline> mesoderm development ; GO:0007498 | traceable author statement <newline> regulation of mitosis ; GO:0007088 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> gastrulation ; GO:0007369 | inferred from mutant phenotype <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> G2/M transition of mitotic cell cycle ; GO:0000086 | non-traceable author statement <newline> G2/M transition of mitotic cell cycle ; GO:0000086 | traceable author statement <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype <newline> M phase of mitotic cell cycle ; GO:0000087 | inferred from electronic annotation with InterPro:IPR000751","chromosome ; GO:0005694 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay","protein tyrosine phosphatase activity ; GO:0004725 | inferred from direct assay <newline> protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement <newline> non-membrane spanning protein tyrosine phosphatase activity ; GO:0004726 | non-traceable author statement"]
[null,"FBgn0004924","Topoisomerase 1","Top1","The gene Topoisomerase 1 is referred to in FlyBase by the symbol Dmel\\Top1 (CG6146, FBgn0004924). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15213525..15222062. It has the cytological map location 13B6. There is experimental evidence that it has the molecular function</span>: DNA topoisomerase activity; DNA topoisomerase type I activity. There is experimental evidence that it is involved in the biological process</span>: instar larval development; cell proliferation; chromosome segregation; DNA topological change; multicellular organismal development; oogenesis; embryonic development; chromosome condensation. 32 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; anatomical structure; female germline cyst; nervous system; germarium; adult brain; egg; cell cycle; imaginal precursor; peripheral nervous system; adult segment. It has 3 annotated transcripts and 3 annotated polypeptides.","embryonic development ; GO:0009790 | inferred from mutant phenotype <newline> instar larval development ; GO:0002168 | inferred from mutant phenotype <newline> multicellular organismal development ; GO:0007275 | inferred from mutant phenotype <newline> DNA topological change ; GO:0006265 | inferred from direct assay <newline> chromosome condensation ; GO:0030261 | inferred from mutant phenotype <newline> chromosome segregation ; GO:0007059 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> DNA unwinding involved in replication ; GO:0006268 | inferred from electronic annotation with InterPro:IPR013030, InterPro:IPR014711, InterPro:IPR014727","cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> polytene chromosome puff ; GO:0005703 | inferred from direct assay <newline> DNA-directed RNA polymerase II, core complex ; GO:0005665 | colocalizes_with inferred from direct assay <newline> nucleolus ; GO:0005730 | inferred from direct assay <newline> nuclear euchromatin ; GO:0005719 | inferred from direct assay <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","DNA topoisomerase type I activity ; GO:0003917 | inferred from sequence or structural similarity with UniProtKB:Q7YR26 <newline> DNA topoisomerase type I activity ; GO:0003917 | non-traceable author statement <newline> DNA topoisomerase type I activity ; GO:0003917 | inferred from direct assay <newline> DNA topoisomerase activity ; GO:0003916 | inferred from direct assay <newline> DNA topoisomerase (ATP-hydrolyzing) activity ; GO:0003918 | inferred from electronic annotation with InterPro:IPR013500"]
[null,"FBgn0011766","E2F transcription factor","E2f","The gene E2F transcription factor is referred to in FlyBase by the symbol Dmel\\E2f (CG6376, FBgn0011766). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17446026..17486127. It has the cytological map location 93E9-93F1. There is experimental evidence that it has the molecular function</span>: protein binding; RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of gene expression; cellular process; dendrite morphogenesis; neuron development; positive regulation of nurse cell apoptosis; muscle tissue development; antimicrobial humoral response; regulation of cell cycle; DNA endoreduplication. 70 alleles are reported. The phenotypes of these alleles are annotated with 31 unique terms, many of which group under: organ system; peripheral nervous system; nervous system; external compound sense organ; female germline cyst; egg; imaginal precursor; adult segment; cell part; primordium; adult mesothoracic segment. It has 3 annotated transcripts and 3 annotated polypeptides.","positive regulation of cell proliferation ; GO:0008284 | non-traceable author statement <newline> positive regulation of nurse cell apoptosis ; GO:0045850 | inferred from mutant phenotype <newline> DNA endoreduplication ; GO:0042023 | inferred from genetic interaction with CycE AND inferred from mutant phenotype <newline> eggshell chorion gene amplification ; GO:0007307 | traceable author statement <newline> G1/S transition of mitotic cell cycle ; GO:0000082 | traceable author statement <newline> imaginal disc development ; GO:0007444 | traceable author statement <newline> nurse cell apoptosis ; GO:0045476 | traceable author statement <newline> positive regulation of transcription ; GO:0045941 | traceable author statement <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> regulation of transcription involved in G1/S-phase of mitotic cell cycle ; GO:0000083 | non-traceable author statement <newline> growth ; GO:0040007 | non-traceable author statement <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | non-traceable author statement <newline> positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> muscle tissue development ; GO:0060537 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003316","nucleus ; GO:0005634 | inferred from direct assay <newline> Rb-E2F complex ; GO:0035189 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","DNA binding ; GO:0003677 | inferred from direct assay <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with Rbf <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription activator activity ; GO:0016563 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with dom inferred from physical interaction with l(3)mbt <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR003316"]
[null,"FBgn0013263","Trithorax-like","Trl","The gene Trithorax-like is referred to in FlyBase by the symbol Dmel\\Trl (CG33261, FBgn0013263). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14741029..14754149. It has the cytological map location 70F4. There is experimental evidence that it has the molecular function</span>: protein binding; specific RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: cellular process; dosage compensation; nuclear division; syncytial blastoderm mitotic cell cycle; imaginal disc-derived wing morphogenesis; protein oligomerization. 68 alleles are reported. The phenotypes of these alleles are annotated with: eye; abdominal segment 6; egg; sex comb; micropyle; wing; imaginal disc; egg chamber; chromatin; denticle belt. It has 9 annotated transcripts and 9 annotated polypeptides.","nuclear division ; GO:0000280 | inferred from mutant phenotype <newline> syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | non-traceable author statement <newline> chromatin organization ; GO:0006325 | non-traceable author statement <newline> dosage compensation ; GO:0007549 | inferred from mutant phenotype <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> positive regulation of transcription, DNA-dependent ; GO:0045893 | traceable author statement <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> protein oligomerization ; GO:0051259 | inferred from direct assay","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> centromeric heterochromatin ; GO:0005721 | inferred from direct assay AND traceable author statement <newline> chromatin ; GO:0000785 | non-traceable author statement","DNA binding ; GO:0003677 | non-traceable author statement <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from mutant phenotype <newline> protein binding ; GO:0005515 | inferred from physical interaction with Ssrp <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P17789 <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P41046 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0015218","Eukaryotic initiation factor 4E","eIF-4E","The gene Eukaryotic initiation factor 4E is referred to in FlyBase by the symbol Dmel\\eIF-4E (CG4035, FBgn0015218). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9392716..9395565. It has the cytological map location 67B4. There is experimental evidence that it has the molecular function</span>: translation initiation factor activity; RNA cap binding. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: cell cycle; cell cycle process; organelle organization; programmed cell death; cellular macromolecule metabolic process; nuclear division; biopolymer biosynthetic process; gland morphogenesis; chromatin organization; cell death; chromosome organization; regulation of biological process. 38 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: nervous system; organ system; peripheral nervous system; external compound sense organ; thoracic segment; cell component; cell cycle; dorsal thoracic disc; multi-cell-component structure; eipithelial furrow; neuromuscular junction; adult segment. It has 7 annotated transcripts and 7 annotated polypeptides.","translation ; GO:0006412 | inferred from sequence or structural similarity with HGNC_gene:EIF4E; HGNC:3287; OMIM:133440 AND inferred from sequence or structural similarity with MGD:Eif4e; MGI:MGI:95305 <newline> RNA metabolic process ; GO:0016070 | inferred from direct assay <newline> translational initiation ; GO:0006413 | inferred from direct assay <newline> translation ; GO:0006412 | non-traceable author statement <newline> positive regulation of cell growth ; GO:0030307 | traceable author statement <newline> regulation of cell growth ; GO:0001558 | inferred from mutant phenotype <newline> RNA metabolic process ; GO:0016070 | non-traceable author statement <newline> translational initiation ; GO:0006413 | non-traceable author statement <newline> chromatin organization ; GO:0006325 | inferred from mutant phenotype <newline> female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype <newline> mitosis ; GO:0007067 | inferred from mutant phenotype <newline> mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype","cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC_gene:EIF4E; HGNC:3287; OMIM:133440 AND inferred from sequence or structural similarity with MGD:Eif4e; MGI:MGI:95305 <newline> eukaryotic translation initiation factor 4F complex ; GO:0016281 | non-traceable author statement <newline> cytosol ; GO:0005829 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> cytosol ; GO:0005829 | inferred from sequence or structural similarity <newline> eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity <newline> postsynaptic density ; GO:0014069 | inferred from direct assay <newline> cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with HGNC_gene:EIF4E; HGNC:3287; OMIM:133440 AND inferred from sequence or structural similarity with MGD:Eif4e; MGI:MGI:95305 <newline> RNA cap binding ; GO:0000339 | inferred from direct assay <newline> translation initiation factor activity ; GO:0003743 | inferred from direct assay <newline> translation initiation factor activity ; GO:0003743 | non-traceable author statement <newline> RNA cap binding ; GO:0000339 | inferred from sequence or structural similarity <newline> translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity <newline> RNA cap binding ; GO:0000339 | non-traceable author statement"]
[null,"FBgn0015790","Rab-protein 11","Rab11","The gene Rab-protein 11 is referred to in FlyBase by the symbol Dmel\\Rab11 (CG5771, FBgn0015790). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16937129..16941877. It has the cytological map location 93B12-93B13. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. There is experimental evidence for 18 unique biological process</span> terms, many of which group under: anatomical structure development; sensory organ development; reproductive process in a multicellular organism; cell division; organ morphogenesis; cell cycle; organelle organization; transport; regulation of cellular component organization; contractile ring contraction involved in cytokinesis during cell cycle; immune response; synaptic transmission; regulation of developmental process; vesicle fusion; actin filament-based process. 44 alleles are reported. The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: peripheral nervous system; nervous system; external compound sense organ; adult segment; cytoplasmic part; organ system; adult mesothoracic segment; intracellular membrane-bounded organelle; spindle; acroblast; rhabdomere; contractile ring; egg; cell division site; imaginal precursor; syncytial blastoderm embryo; garland cell; late extended germ band embryo. It has 2 annotated transcripts and 2 annotated polypeptides.","regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype <newline> endocytosis ; GO:0006897 | inferred from mutant phenotype <newline> oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype <newline> actin cytoskeleton reorganization ; GO:0031532 | inferred from mutant phenotype <newline> rhabdomere development ; GO:0042052 | inferred from mutant phenotype <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> cellularization ; GO:0007349 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from genetic interaction with bchs <newline> bristle development ; GO:0022416 | inferred from mutant phenotype <newline> regulation of synapse organization ; GO:0050807 | inferred from mutant phenotype <newline> endocytosis ; GO:0006897 | inferred from direct assay <newline> sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype <newline> spermatocyte division ; GO:0048137 | inferred from mutant phenotype <newline> contractile ring contraction involved in cell cycle cytokinesis ; GO:0000916 | inferred from mutant phenotype <newline> Golgi vesicle fusion to target membrane ; GO:0048210 | inferred from mutant phenotype <newline> small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579 <newline> protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR003579","trans-Golgi network transport vesicle ; GO:0030140 | inferred from direct assay <newline> terminal button ; GO:0043195 | inferred from direct assay <newline> centrosome ; GO:0005813 | colocalizes_with inferred from direct assay <newline> endosome ; GO:0005768 | inferred from direct assay <newline> lipid particle ; GO:0005811 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> vesicle ; GO:0031982 | inferred from direct assay <newline> cell pole ; GO:0060187 | inferred from direct assay <newline> cleavage furrow ; GO:0032154 | inferred from direct assay <newline> Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> spindle envelope ; GO:0070732 | inferred from direct assay <newline> nuclear envelope ; GO:0005635 | inferred from direct assay <newline> perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay","GTPase activity ; GO:0003924 | inferred from sequence or structural similarity <newline> GTP binding ; GO:0005525 | non-traceable author statement <newline> GTPase activity ; GO:0003924 | non-traceable author statement <newline> GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225"]
[null,"FBgn0023215","Mnt","Mnt","The gene Mnt is referred to in FlyBase by the symbol Dmel\\Mnt (CG13316, FBgn0023215). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3565834..3594813. It has the cytological map location 3E4-3E5. There is experimental evidence that it has the molecular function</span>: protein binding; sequence-specific DNA binding; transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription; regulation of cell cycle; negative regulation of cell growth; phagocytosis, engulfment. 32 alleles are reported. The phenotypes of these alleles are annotated with: eye; adult head; ommatidium; wing hair. It has 7 annotated transcripts and 7 annotated polypeptides.","regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with dm <newline> regulation of transcription ; GO:0045449 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> negative regulation of cell growth ; GO:0030308 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity <newline> nucleus ; GO:0005634 | inferred by curator from GO:0003700 <newline> nucleus ; GO:0005634 | inferred from direct assay","RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with dm <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q99583 <newline> protein binding ; GO:0005515 | inferred from physical interaction with Max <newline> sequence-specific DNA binding ; GO:0043565 | inferred from direct assay <newline> transcription repressor activity ; GO:0016564 | inferred from direct assay"]
[null,"FBgn0024308","Smrter","Smr","The gene Smrter is referred to in FlyBase by the symbol Dmel\\Smr (CG4013, FBgn0024308). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:12580031..12636476. It has the cytological map location 11B10-11B14. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: regulation of mitotic cell cycle; phagocytosis, engulfment. 25 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","negative regulation of transcription, DNA-dependent ; GO:0045892 | traceable author statement <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype","polytene chromosome ; GO:0005700 | non-traceable author statement","transcription corepressor activity ; GO:0003714 | non-traceable author statement <newline> protein binding ; GO:0005515 | traceable author statement <newline> transcription corepressor activity ; GO:0003714 | traceable author statement <newline> transcription corepressor activity ; GO:0003714 | inferred from sequence or structural similarity with EMBL:AF125672; protein_id:AAD22973.1 <newline> protein binding ; GO:0005515 | inferred from physical interaction with Su(H) <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001005"]
[null,"FBgn0026143","CDC45L","CDC45L","The gene CDC45L is referred to in FlyBase by the symbol Dmel\\CDC45L (CG3658, FBgn0026143). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:922324..924606. It has the cytological map location 1E1. There is experimental evidence that it has the molecular function</span>: 3'-5' DNA helicase activity; chromatin binding. There is experimental evidence that it is involved in the biological process</span>: DNA amplification; DNA replication; positive regulation of S phase of mitotic cell cycle; chromosome condensation. 4 alleles are reported. The phenotype of these alleles is annotated with: nuclear chromosome. It has one annotated transcript and one annotated polypeptide.","DNA amplification ; GO:0006277 | inferred from expression pattern <newline> DNA replication ; GO:0006260 | inferred from physical interaction with Mcm5 AND inferred from physical interaction with dpa <newline> DNA replication initiation ; GO:0006270 | inferred from sequence or structural similarity with HGNC_gene:CDC45L; HGNC:1739; OMIM:603465 AND inferred from sequence or structural similarity with SGD_LOCUS:CDC45; SGD:S0004093 <newline> chromosome condensation ; GO:0030261 | inferred from mutant phenotype <newline> DNA replication ; GO:0006260 | inferred from sequence or structural similarity with EMBL:AF062494 <newline> positive regulation of S phase of mitotic cell cycle ; GO:0045750 | inferred from mutant phenotype <newline> DNA replication initiation ; GO:0006270 | inferred from electronic annotation with InterPro:IPR003874","cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> pre-replicative complex ; GO:0005656 | inferred from physical interaction with Mcm5 AND inferred from physical interaction with dpa AND inferred from sequence or structural similarity with HGNC_gene:CDC45L; HGNC:1739; OMIM:603465 AND inferred from sequence or structural similarity with SGD_LOCUS:CDC45; SGD:S0004093 <newline> pre-replicative complex ; GO:0005656 | inferred from sequence or structural similarity with EMBL:AF062494","chromatin binding ; GO:0003682 | inferred from direct assay <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity with EMBL:AF062494 <newline> 3'-5' DNA helicase activity ; GO:0043138 | contributes_to inferred from direct assay"]
[null,"FBgn0034878","pita","pita","The gene pita is referred to in FlyBase by the symbol Dmel\\pita (CG3941, FBgn0034878). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19436488..19442241. It has the cytological map location 59E3. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: DNA replication; DNA endoreduplication. 26 alleles are reported. The phenotypes of these alleles are annotated with: larval salivary gland; condensed nuclear chromosome; mitotic anaphase; spindle; imaginal disc; G2 phase of mitotic cell cycle; mitotic metaphase; larval tracheal system. It has 2 annotated transcripts and 2 annotated polypeptides.","mitosis ; GO:0007067 | non-traceable author statement <newline> DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype <newline> DNA replication ; GO:0006260 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay","DNA binding ; GO:0003677 | inferred from direct assay <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR012934, InterPro:IPR015880"]
[null,"FBgn0040232","CENP-meta","cmet","The gene CENP-meta is referred to in FlyBase by the symbol Dmel\\cmet (CG6392, FBgn0040232). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:11260823..11269179. It has the cytological map location 32E2. Based on sequence similarity, it is predicted to have molecular function</span>: plus-end-directed microtubule motor activity; microtubule motor activity. There is experimental evidence that it is involved in the biological process</span>: mitotic metaphase plate congression; mitotic spindle organization; cell cycle. 6 alleles are reported. The phenotypes of these alleles are annotated with: spindle microtubule; mitotic cell cycle; condensed nuclear chromosome; spindle pole; spermatocyte; astral microtubule. It has one annotated transcript and one annotated polypeptide.","mitotic metaphase plate congression ; GO:0007080 | non-traceable author statement <newline> mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype <newline> microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity <newline> cell cycle ; GO:0007049 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype <newline> microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821","chromosome, centromeric region ; GO:0000775 | non-traceable author statement <newline> kinetochore ; GO:0000776 | non-traceable author statement <newline> kinetochore ; GO:0000776 | inferred from direct assay <newline> kinesin complex ; GO:0005871 | inferred from sequence or structural similarity <newline> outer kinetochore of condensed chromosome ; GO:0000940 | non-traceable author statement <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","microtubule motor activity ; GO:0003777 | non-traceable author statement <newline> plus-end-directed microtubule motor activity ; GO:0008574 | inferred from sequence or structural similarity with HGNC_gene:CENPE; HGNC:1856; OMIM:117143 <newline> microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity <newline> microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity with EMBL:AF027728 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821"]
[null,"FBgn0086899","Tousled-like kinase","tlk","The gene Tousled-like kinase is referred to in FlyBase by the symbol Dmel\\tlk (CG34412, FBgn0086899). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3614054..3682010. It has the cytological map location 3F1-3E7. There is experimental evidence that it has the molecular function</span>: protein binding; protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; protein amino acid autophosphorylation; mitotic cell cycle, embryonic; chromatin organization; chromosome segregation; protein amino acid phosphorylation; cell adhesion; histone phosphorylation; antimicrobial humoral response; regulation of cell cycle. 83 alleles are reported. The phenotypes of these alleles are annotated with: larval salivary gland; eye; macrochaeta; head. It has 8 annotated transcripts and 8 annotated polypeptides.","protein amino acid phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with EMBL:AF045253 <newline> cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> chromatin organization ; GO:0006325 | inferred from genetic interaction with asf1 <newline> histone phosphorylation ; GO:0016572 | inferred from mutant phenotype <newline> mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype <newline> protein amino acid autophosphorylation ; GO:0046777 | inferred from direct assay <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype <newline> chromosome segregation ; GO:0007059 | inferred from genetic interaction with mars","nucleus ; GO:0005634 | inferred from direct assay","protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with EMBL:AF045253 <newline> protein kinase activity ; GO:0004672 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with asf1 <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC_gene:TLK1; HGNC:11841; OMIM:608438 AND inferred from sequence or structural similarity with HGNC_gene:TLK2; HGNC:11842; OMIM:608439 AND inferred from sequence or structural similarity with TAIR:gene:1944622 <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with EMBL:AF045252; protein_id:AAC02225.1 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0243512","puckered","puc","The gene puckered is referred to in FlyBase by the symbol Dmel\\puc (CG7850, FBgn0243512). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3931057..3948023. It has the cytological map location 84E12-84E11. There is experimental evidence that it has the molecular function</span>: JUN kinase phosphatase activity; phosphoprotein phosphatase activity. There is experimental evidence for 20 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; organ development; organ morphogenesis; regulation of biological process; actin filament-based process; ovarian follicle cell development; regulation of developmental process; response to stress; organelle organization. 54 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; egg; cuticle; peripheral nervous system; external compound sense organ; adult segment; nervous system; chorion; adult mesothoracic segment; cuticular specialization. It has one annotated transcript and one annotated polypeptide.","imaginal disc eversion ; GO:0007561 | inferred from mutant phenotype <newline> imaginal disc fusion ; GO:0046528 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> epidermis development ; GO:0008544 | inferred from mutant phenotype <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> JNK cascade ; GO:0007254 | non-traceable author statement <newline> suture of dorsal opening ; GO:0007396 | non-traceable author statement <newline> JNK cascade ; GO:0007254 | inferred from mutant phenotype <newline> actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype <newline> protein amino acid dephosphorylation ; GO:0006470 | inferred from direct assay AND inferred from sequence or structural similarity <newline> protein amino acid dephosphorylation ; GO:0006470 | non-traceable author statement <newline> JNK cascade ; GO:0007254 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> wound healing ; GO:0042060 | inferred from expression pattern <newline> negative regulation of JNK cascade ; GO:0046329 | traceable author statement <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> response to oxidative stress ; GO:0006979 | inferred from mutant phenotype <newline> wound healing ; GO:0042060 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> negative regulation of JNK cascade ; GO:0046329 | non-traceable author statement <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> micropyle formation ; GO:0046844 | inferred from mutant phenotype <newline> wound healing ; GO:0042060 | inferred from direct assay <newline> dorsal closure ; GO:0007391 | non-traceable author statement <newline> ommatidial rotation ; GO:0016318 | non-traceable author statement <newline> establishment of planar polarity ; GO:0001736 | non-traceable author statement <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Pvr <newline> regulation of G2/M transition of mitotic cell cycle ; GO:0010389 | inferred from mutant phenotype","Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay","MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | non-traceable author statement <newline> JUN kinase phosphatase activity ; GO:0008579 | inferred from mutant phenotype <newline> phosphoprotein phosphatase activity ; GO:0004721 | inferred from direct assay <newline> protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity <newline> protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from sequence or structural similarity <newline> JUN kinase phosphatase activity ; GO:0008579 | non-traceable author statement <newline> JUN kinase phosphatase activity ; GO:0008579 | traceable author statement <newline> protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement <newline> MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | traceable author statement <newline> protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130"]
[null,"FBgn0261618","La related protein","larp","The gene La related protein is referred to in FlyBase by the symbol Dmel\\larp (CG42551, FBgn0261618). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:24143896..24162162. It has the cytological map location 98C3-98C4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: mitochondrion inheritance; mitotic chromosome condensation; centrosome separation; spindle assembly involved in male meiosis; syncytial blastoderm mitotic cell cycle; male meiosis; spindle assembly; autophagic cell death; salivary gland cell autophagic cell death. 35 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; peripheral nervous system; nervous system; cytoplasmic part; intracellular membrane-bounded organelle; nucleus; intracellular organelle part; nuclear part; spermatocyte; spindle; cell cycle; external compound sense organ. It has 4 annotated transcripts and 4 annotated polypeptides.","centrosome separation ; GO:0051299 | inferred from mutant phenotype <newline> mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> spindle assembly ; GO:0051225 | inferred from mutant phenotype <newline> mitochondrion inheritance ; GO:0000001 | inferred from mutant phenotype <newline> male meiosis ; GO:0007140 | inferred from mutant phenotype <newline> spindle assembly involved in male meiosis ; GO:0007053 | inferred from mutant phenotype <newline> syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay <newline> cytosol ; GO:0005829 | inferred from direct assay <newline> mitochondrion ; GO:0005739 | colocalizes_with inferred from direct assay","molecular_function ; GO:0003674 | no biological data available"]
[null,"FBgn0259789","vielfaltig","vfl","The gene vielfaltig is referred to in FlyBase by the symbol Dmel\\vfl (CG12701, FBgn0259789). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding. There is experimental evidence that it is involved in the biological process</span>: mitotic cell cycle. 9 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; peripheral nervous system; anatomical structure; adult segment; embryonic nervous system; thoracic segment; integumentary plate; developing anatomical structure; cell part; embryonic neuron. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Zinc finger, C2H2-like; Zinc finger, C2H2-type; Zinc finger, C2H2-type/integrase, DNA-binding; Zinc finger, double-stranded RNA binding. Gene sequence location is X:19670020..19676961.","mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype","chromatin ; GO:0000785 | colocalizes_with inferred from direct assay <newline> nucleoplasm ; GO:0005654 | inferred from direct assay","sequence-specific DNA binding ; GO:0043565 | inferred from direct assay <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0037751","matotopetli","topi","The gene matotopetli is referred to in FlyBase by the symbol Dmel\\topi (CG8484, FBgn0037751). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: male meiosis; positive regulation of transcription, meiotic; spermatogenesis. 5 alleles are reported. The phenotypes of these alleles are annotated with: secondary spermatocyte; spermatid. It has one annotated transcript and one annotated polypeptide. Protein features are: Zinc finger, C2H2-like; Zinc finger, C2H2-type; Zinc finger, C2H2-type/integrase, DNA-binding. Gene sequence location is 3R:5600843..5603665.","male meiosis ; GO:0007140 | inferred from mutant phenotype <newline> spermatogenesis ; GO:0007283 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> positive regulation of transcription during meiosis ; GO:0051039 | inferred from mutant phenotype","nucleus ; GO:0005634 | non-traceable author statement <newline> nuclear chromatin ; GO:0000790 | inferred from direct assay","DNA binding ; GO:0003677 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087"]
[null,"FBgn0004066","Proteasome 28kD subunit 1","Pros28.1","The gene Proteasome 28kD subunit 1 is referred to in FlyBase by the symbol Dmel\\Pros28.1 (CG3422, FBgn0004066). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: response to DNA damage stimulus. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Proteasome, alpha-subunit, conserved site; Proteasome, subunit alpha/beta. Gene sequence location is X:16170305..16171621.","ubiquitin-dependent protein catabolic process ; GO:0006511 | non-traceable author statement <newline> proteolysis ; GO:0006508 | non-traceable author statement <newline> response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype <newline> ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR000426","proteasome core complex ; GO:0005839 | inferred from sequence or structural similarity with EMBL:AF019662 <newline> proteasome complex ; GO:0000502 | non-traceable author statement <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay <newline> proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from electronic annotation with InterPro:IPR000426","endopeptidase activity ; GO:0004175 | inferred from sequence or structural similarity with EMBL:AF019662 <newline> endopeptidase activity ; GO:0004175 | non-traceable author statement <newline> threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353"]
[null,"FBgn0035233","peroxin 10","pex10","The gene peroxin 10 is referred to in FlyBase by the symbol Dmel\\pex10 (CG7864, FBgn0035233). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. There is experimental evidence that it is involved in the biological process</span>: male meiosis cytokinesis; spermatid development; primary spermatocyte growth; spermatocyte division. 10 alleles are reported. The phenotypes of these alleles are annotated with: spermatid; testis. It has one annotated transcript and one annotated polypeptide. Protein features are: Pex, N-terminal; Zinc finger, C3HC4 RING-type; Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Gene sequence location is 3L:1558235..1559863.","peroxisome organization ; GO:0007031 | inferred from sequence or structural similarity with NCBI_gi:4505715 <newline> spermatid development ; GO:0007286 | inferred from mutant phenotype <newline> primary spermatocyte growth ; GO:0007285 | inferred from mutant phenotype <newline> male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype <newline> spermatocyte division ; GO:0048137 | inferred from mutant phenotype","peroxisomal membrane ; GO:0005778 | inferred from electronic annotation with InterPro:IPR006845","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841"]
[null,"FBgn0023180","Origin recognition complex subunit 6","Orc6","The gene Origin recognition complex subunit 6 is referred to in FlyBase by the symbol Dmel\\Orc6 (CG1584, FBgn0023180). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of GTPase activity; DNA-dependent DNA replication initiation; mitosis; DNA replication; M phase of mitotic cell cycle. 14 alleles are reported. The phenotypes of these alleles are annotated with: embryonic salivary gland; imaginal disc; embryonic/larval brain; larval optic lobe. It has one annotated transcript and one annotated polypeptide. Protein features are: Origin recognition complex, subunit 6; Origin recognition complex, subunit 6, metazoa/plant. Gene sequence location is 2R:5732964..5733964.","DNA-dependent DNA replication initiation ; GO:0006270 | inferred from sequence or structural similarity with EMBL:AF139659; protein_id:AAD32667.1 <newline> DNA-dependent DNA replication initiation ; GO:0006270 | inferred from direct assay <newline> DNA-dependent DNA replication ; GO:0006261 | non-traceable author statement <newline> chromatin silencing ; GO:0006342 | non-traceable author statement <newline> DNA replication ; GO:0006260 | inferred from direct assay <newline> mitosis ; GO:0007067 | inferred from mutant phenotype <newline> M phase of mitotic cell cycle ; GO:0000087 | inferred from mutant phenotype <newline> positive regulation of GTPase activity ; GO:0043547 | inferred from direct assay","nuclear origin of replication recognition complex ; GO:0005664 | inferred from sequence or structural similarity with EMBL:AF139659; protein_id:AAD32667.1 <newline> nuclear origin of replication recognition complex ; GO:0005664 | inferred from direct assay <newline> nuclear origin of replication recognition complex ; GO:0005664 | non-traceable author statement <newline> origin recognition complex ; GO:0000808 | inferred from direct assay <newline> plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay <newline> septin complex ; GO:0031105 | colocalizes_with inferred from direct assay","DNA binding ; GO:0003677 | non-traceable author statement <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR008721"]
[null,"FBgn0016792","dalmatian","dmt","The gene dalmatian is referred to in FlyBase by the symbol Dmel\\dmt (CG8374, FBgn0016792). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: mitotic sister chromatid cohesion; nervous system development; mitotic spindle organization. 11 alleles are reported. The phenotype of these alleles is annotated with: peripheral nervous system. It has one annotated transcript and one annotated polypeptide. Protein features are: HMG-I/HMG-Y, DNA-binding, conserved site. Gene sequence location is 3R:5536862..5540397.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | inferred from mutant phenotype <newline> mitotic sister chromatid cohesion ; GO:0007064 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000637","chromatin ; GO:0000785 | colocalizes_with inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from sequence model","-"]
[null,"FBgn0040233","CENP-ana","cana","The gene CENP-ana is referred to in FlyBase by the symbol Dmel\\cana (CG33694, FBgn0040233). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: plus-end-directed microtubule motor activity; microtubule motor activity. There is experimental evidence that it is involved in the biological process</span>: mitotic anaphase. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Kinesin, motor domain; Kinesin, motor region, conserved site. Gene sequence location is 2L:11269727..11279847.","mitotic anaphase ; GO:0000090 | inferred from mutant phenotype <newline> microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity <newline> microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821","kinesin complex ; GO:0005871 | inferred from sequence or structural similarity <newline> kinesin complex ; GO:0005871 | inferred from sequence or structural similarity with MGD:Kif5b; MGI:MGI:1098268","microtubule motor activity ; GO:0003777 | non-traceable author statement <newline> plus-end-directed microtubule motor activity ; GO:0008574 | inferred from sequence or structural similarity with HGNC_gene:CENPE; HGNC:1856; OMIM:117143 <newline> microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity <newline> microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity with MGD:Kif5b; MGI:MGI:1098268 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821"]
[null,"FBgn0017545","Ribosomal protein S3A","RpS3A","The gene Ribosomal protein S3A is referred to in FlyBase by the symbol Dmel\\RpS3A (CG2168, FBgn0017545). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of ribosome. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle elongation; mitotic spindle organization. 6 alleles are reported. The phenotypes of these alleles are annotated with: adult; macrochaeta. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Ribosomal protein S3Ae; Ribosomal protein S3Ae, conserved site. Gene sequence location is 4:86745..87863.","translation ; GO:0006412 | non-traceable author statement <newline> translation ; GO:0006412 | inferred from sequence or structural similarity with HGNC_gene:RPS3A; HGNC:10421; OMIM:180478 <newline> oogenesis ; GO:0048477 | non-traceable author statement <newline> mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype","lipid particle ; GO:0005811 | inferred from direct assay <newline> cytosolic ribosome ; GO:0022626 | non-traceable author statement <newline> cytosolic small ribosomal subunit ; GO:0022627 | non-traceable author statement <newline> cytosolic small ribosomal subunit ; GO:0022627 | inferred from sequence or structural similarity with HGNC_gene:RPS3A; HGNC:10421; OMIM:180478","structural constituent of ribosome ; GO:0003735 | non-traceable author statement <newline> structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with HGNC_gene:RPS3A; HGNC:10421; OMIM:180478"]
[null,"FBgn0032154","-","CG5924","This gene is referred to in FlyBase by the symbol Dmel\\CG5924 (FBgn0032154). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: DNA helicase activity; ATP binding. There is experimental evidence that it is involved in the biological process</span>: mitochondrial genome maintenance; protein homooligomerization. 15 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: DNA helicase, DnaB-like, C-terminal. Gene sequence location is 2L:9891255..9893419.","mitochondrial genome maintenance ; GO:0000002 | inferred from mutant phenotype <newline> protein homooligomerization ; GO:0051260 | inferred from direct assay <newline> DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR007694","mitochondrion ; GO:0005739 | inferred from direct assay","DNA helicase activity ; GO:0003678 | inferred from electronic annotation with InterPro:IPR007694 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR007694"]
[null,"FBgn0022764","Sin3A","Sin3A","The gene Sin3A is referred to in FlyBase by the symbol Dmel\\Sin3A (CG8815, FBgn0022764). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of transcription; dendrite morphogenesis; neuron development; regulation of mitotic cell cycle; muscle organ development; negative regulation of transcription, DNA-dependent. 59 alleles are reported. The phenotypes of these alleles are annotated with: embryonic heart; mitochondrion; crystal cell. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Histone deacetylase interacting; Paired amphipathic helix. Gene sequence location is 2R:8462745..8480397.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> negative regulation of transcription ; GO:0016481 | inferred from expression pattern <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with SGD_LOCUS:SIN3; SGD:S0005364 <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | traceable author statement <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype <newline> negative regulation of transcription ; GO:0016481 | inferred from direct assay","nucleus ; GO:0005634 | non-traceable author statement <newline> chromatin ; GO:0000785 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> Sin3 complex ; GO:0016580 | non-traceable author statement <newline> euchromatin ; GO:0000791 | traceable author statement <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD_LOCUS:SIN3; SGD:S0005364 <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> polytene chromosome ; GO:0005700 | inferred from direct assay","RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | inferred from mutant phenotype <newline> sequence-specific DNA binding transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with SGD_LOCUS:SIN3; SGD:S0005364 <newline> transcription cofactor activity ; GO:0003712 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | inferred from direct assay"]
[null,"FBgn0035120","wee Augmin","wac","The gene wee Augmin is referred to in FlyBase by the symbol Dmel\\wac (CG13879, FBgn0035120). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: protein binding; microtubule binding. There is experimental evidence that it is involved in the biological process</span>: female meiosis; mitotic spindle organization; cytoplasmic microtubule organization; spindle assembly; cell division. 7 alleles are reported. The phenotypes of these alleles are annotated with: eye; macrochaeta; adult cuticle; spindle. It has 2 annotated transcripts and 2 annotated polypeptides. Gene sequence location is 3L:258350..259097.","cell division ; GO:0051301 | inferred from mutant phenotype <newline> spindle assembly ; GO:0051225 | inferred from mutant phenotype <newline> female meiosis ; GO:0007143 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype <newline> cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype","protein complex ; GO:0043234 | inferred from direct assay inferred from genetic interaction with dgt2 <newline> spindle ; GO:0005819 | inferred from direct assay <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with dgt2 <newline> microtubule binding ; GO:0008017 | inferred from direct assay"]
[null,"FBgn0040070","thioredoxin-2","Trx-2","The gene thioredoxin-2 is referred to in FlyBase by the symbol Dmel\\Trx-2 (CG31884, FBgn0040070). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: disulfide oxidoreductase activity. There is experimental evidence that it is involved in the biological process</span>: cell redox homeostasis; determination of adult lifespan; response to DNA damage stimulus; response to oxidative stress. 17 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Thioredoxin; Thioredoxin domain; Thioredoxin fold; Thioredoxin, conserved site; Thioredoxin-like; Thioredoxin-like fold. Gene sequence location is 2L:9613165..9616048.","cell redox homeostasis ; GO:0045454 | inferred from direct assay <newline> determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> response to oxidative stress ; GO:0006979 | inferred from mutant phenotype <newline> response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype <newline> glycerol ether metabolic process ; GO:0006662 | inferred from electronic annotation with InterPro:IPR005746","nucleus ; GO:0005634 | inferred from direct assay","disulfide oxidoreductase activity ; GO:0015036 | non-traceable author statement <newline> disulfide oxidoreductase activity ; GO:0015036 | inferred from direct assay <newline> disulfide oxidoreductase activity ; GO:0015036 | inferred from sequence or structural similarity with SGD_LOCUS:TRX1; SGD:S0004033 <newline> electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR005746 <newline> protein disulfide oxidoreductase activity ; GO:0015035 | inferred from electronic annotation with InterPro:IPR005746"]
[null,"FBgn0027259","kinetochore Mis12-Ndc80 network component 1","Kmn1","The gene kinetochore Mis12-Ndc80 network component 1 is referred to in FlyBase by the symbol Dmel\\Kmn1 (CG1558, FBgn0027259). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: mitotic metaphase plate congression; chromosome segregation. 12 alleles are reported. The phenotypes of these alleles are annotated with: metaphase; condensed nuclear chromosome; nucleus. It has one annotated transcript and one annotated polypeptide. Gene sequence location is X:11465400..11466475.","mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype <newline> chromosome segregation ; GO:0007059 | inferred from mutant phenotype","kinetochore ; GO:0000776 | inferred from direct assay <newline> NMS complex ; GO:0031617 | inferred from sequence or structural similarity with HGNC_gene:NSL1; HGNC:24548; OMIM:609174 <newline> Ndc80 complex ; GO:0031262 | inferred from direct assay","-"]
[null,"FBgn0001942","Eukaryotic initiation factor 4a","eIF-4a","The gene Eukaryotic initiation factor 4a is referred to in FlyBase by the symbol Dmel\\eIF-4a (CG9075, FBgn0001942). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: translation initiation factor activity; RNA helicase activity. There is experimental evidence that it is involved in the biological process</span>: germ-line stem cell maintenance; mitotic spindle elongation; response to DNA damage stimulus; mitosis; mitotic spindle organization; dorsal/ventral axis specification; oogenesis; female germ-line stem cell division; regulation of alternative nuclear mRNA splicing, via spliceosome. 66 alleles are reported. The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: anatomical structure; developing anatomical structure; organ system; cuticle; peripheral nervous system; nervous system; parasegment 9; dorsal thoracic disc; multi-cell-component structure; parasegment 14; parasegment 2; cephalopharyngeal skeleton; external compound sense organ; late extended germ band embryo. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: DEAD-like helicase, N-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Helicase, superfamily 1/2, ATP-binding domain; RNA helicase, ATP-dependent, DEAD-box, conserved site; RNA helicase, DEAD-box type, Q motif. Gene sequence location is 2L:5981759..5985572.","dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype <newline> translational initiation ; GO:0006413 | inferred from sequence or structural similarity with SGD_LOCUS:TIF1; SGD:S0001767 <newline> translational initiation ; GO:0006413 | non-traceable author statement <newline> imaginal disc growth ; GO:0007446 | traceable author statement <newline> instar larval development ; GO:0002168 | traceable author statement <newline> translational initiation ; GO:0006413 | inferred from sequence or structural similarity <newline> DNA unwinding involved in replication ; GO:0006268 | non-traceable author statement <newline> regulation of alternative nuclear mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype <newline> mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from genetic interaction with bam <newline> female germ-line stem cell division ; GO:0048132 | inferred from genetic interaction with bam inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype <newline> mitosis ; GO:0007067 | inferred from mutant phenotype","eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity with SGD_LOCUS:TIF1; SGD:S0001767 <newline> cytosol ; GO:0005829 | non-traceable author statement <newline> cytosol ; GO:0005829 | inferred from sequence or structural similarity <newline> eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity <newline> nucleus ; GO:0005634 | inferred by curator from GO:0000381 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity <newline> translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD_LOCUS:TIF1; SGD:S0001767 <newline> translation initiation factor activity ; GO:0003743 | non-traceable author statement <newline> RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity with SGD_LOCUS:TIF2; SGD:S0003674 <newline> translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity <newline> RNA cap binding ; GO:0000339 | non-traceable author statement <newline> mRNA binding ; GO:0003729 | non-traceable author statement <newline> single-stranded DNA-dependent ATP-dependent DNA helicase activity ; GO:0017116 | non-traceable author statement <newline> ATP-dependent helicase activity ; GO:0008026 | inferred from electronic annotation with InterPro:IPR000629, InterPro:IPR011545 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000629, InterPro:IPR001650, InterPro:IPR011545"]
[null,"FBgn0261618","La related protein","larp","The gene La related protein is referred to in FlyBase by the symbol Dmel\\larp (CG42551, FBgn0261618). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: mitochondrion inheritance; mitotic chromosome condensation; centrosome separation; spindle assembly involved in male meiosis; syncytial blastoderm mitotic cell cycle; male meiosis; spindle assembly; autophagic cell death; salivary gland cell autophagic cell death. 35 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; organelle; peripheral nervous system; cytoplasmic part; anatomical structure; nucleus; nuclear part; cell cycle; external compound sense organ; male organism; sense organ. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Protein of unknown function DM15; RNA-binding protein Lupus La; Winged helix-turn-helix transcription repressor DNA-binding. Gene sequence location is 3R:24143905..24162162.","centrosome separation ; GO:0051299 | inferred from mutant phenotype <newline> mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> spindle assembly ; GO:0051225 | inferred from mutant phenotype <newline> mitochondrion inheritance ; GO:0000001 | inferred from mutant phenotype <newline> male meiosis ; GO:0007140 | inferred from mutant phenotype <newline> spindle assembly involved in male meiosis ; GO:0007053 | inferred from mutant phenotype <newline> syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay <newline> cytosol ; GO:0005829 | inferred from direct assay <newline> mitochondrion ; GO:0005739 | colocalizes_with inferred from direct assay","molecular_function ; GO:0003674 | no biological data available"]
[null,"FBgn0260634","eukaryotic translation initiation factor 4G2","eIF4G2","The gene eukaryotic translation initiation factor 4G2 is referred to in FlyBase by the symbol Dmel\\eIF4G2 (CG10192, FBgn0260634). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: RNA 7-methylguanosine cap binding. There is experimental evidence that it is involved in the biological process</span>: spermatid differentiation; G1/S transition of mitotic cell cycle; meiotic G2/MI transition; male meiosis; autophagic cell death; salivary gland cell autophagic cell death; spermatogenesis. 10 alleles are reported. The phenotypes of these alleles are annotated with: spermatid; testis; spermatocyte; spermatozoon. It has one annotated transcript and one annotated polypeptide. Protein features are: Armadillo-type fold; Initiation factor eIF-4 gamma, MA3; MIF4-like, type 1/2/3; MIF4G-like, type 3. Gene sequence location is 3R:19635550..19644364.","male meiosis ; GO:0007140 | inferred from mutant phenotype <newline> meiotic G2/MI transition ; GO:0008315 | inferred from mutant phenotype <newline> spermatid differentiation ; GO:0048515 | inferred from mutant phenotype <newline> G1/S transition of mitotic cell cycle ; GO:0000082 | inferred from genetic interaction with eIF4G <newline> translational initiation ; GO:0006413 | inferred from sequence or structural similarity with UniProtKB:P41110 <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> spermatogenesis ; GO:0007283 | inferred from mutant phenotype <newline> RNA metabolic process ; GO:0016070 | inferred from electronic annotation with InterPro:IPR003890, InterPro:IPR016021","eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity with UniProtKB:P41110","RNA 7-methylguanosine cap binding ; GO:0000340 | inferred from direct assay <newline> translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with UniProtKB:P41110"]
[null,"FBgn0004655","wings apart-like","wapl","The gene wings apart-like is referred to in FlyBase by the symbol Dmel\\wapl (CG3707, FBgn0004655). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. There is experimental evidence that it is involved in the biological process</span>: female meiosis chromosome segregation; sister chromatid cohesion. 37 alleles are reported. The phenotypes of these alleles are annotated with: eye; wing; tergite; wing vein. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Armadillo-like helical; Armadillo-type fold; Wings apart-like protein; Wings apart-like, metazoan/plants. Gene sequence location is X:2044135..2053016.","sister chromatid cohesion ; GO:0007062 | inferred from mutant phenotype <newline> female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype","cellular_component ; GO:0005575 | no biological data available","binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR011989, InterPro:IPR016024"]
[null,"FBgn0010621","T-complex Chaperonin 5","Cct5","The gene T-complex Chaperonin 5 is referred to in FlyBase by the symbol Dmel\\Cct5 (CG8439, FBgn0010621). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled; unfolded protein binding. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle organization. 10 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Chaperone, tailless complex polypeptide 1; Chaperonin Cpn60/TCP-1; Chaperonin TCP-1, conserved site; T-complex protein 1, epsilon subunit. Gene sequence location is 2R:8062281..8065039.","protein folding ; GO:0006457 | inferred from sequence or structural similarity <newline> protein folding ; GO:0006457 | inferred from sequence or structural similarity with UniProtKB:P48643 <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype","chaperonin-containing T-complex ; GO:0005832 | inferred from sequence or structural similarity <newline> chaperonin-containing T-complex ; GO:0005832 | inferred from sequence or structural similarity with UniProtKB:P48643 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity <newline> ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity with UniProtKB:P48643 <newline> unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with UniProtKB:P48643 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR002194, InterPro:IPR002423, InterPro:IPR012718"]
[null,"FBgn0026015","Topoisomerase 3beta","Top3beta","The gene Topoisomerase 3? is referred to in FlyBase by the symbol Dmel\\Top3? (CG3458, FBgn0026015). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6178171..6181997. It has the cytological map location 5E5. There is experimental evidence that it has the molecular function</span>: DNA topoisomerase activity; endodeoxyribonuclease activity. There is experimental evidence that it is involved in the biological process</span>: DNA catabolic process, endonucleolytic. 13 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","DNA catabolic process, endonucleolytic ; GO:0000737 | inferred from direct assay <newline> DNA topological change ; GO:0006265 | inferred from electronic annotation with InterPro:IPR000380, InterPro:IPR003601, InterPro:IPR003602, InterPro:IPR013497, InterPro:IPR013824, InterPro:IPR013826 <newline> DNA unwinding involved in replication ; GO:0006268 | inferred from electronic annotation with InterPro:IPR013824, InterPro:IPR013826","chromosome ; GO:0005694 | inferred from electronic annotation with InterPro:IPR000380, InterPro:IPR003601, InterPro:IPR003602, InterPro:IPR013497, InterPro:IPR013824, InterPro:IPR013826","DNA topoisomerase activity ; GO:0003916 | non-traceable author statement <newline> DNA topoisomerase activity ; GO:0003916 | inferred from direct assay <newline> endodeoxyribonuclease activity ; GO:0004520 | inferred from direct assay <newline> DNA topoisomerase type I activity ; GO:0003917 | inferred from sequence or structural similarity with SGD_LOCUS:TOP3; SGD:S0004224 <newline> DNA topoisomerase type I activity ; GO:0003917 | non-traceable author statement"]
[null,"FBgn0023175","Proteasome alpha7 subunit","Prosalpha7","The gene Proteasome ?7 subunit is referred to in FlyBase by the symbol Dmel\\Pros?7 (CG1519, FBgn0023175). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:5734141..5735339. It has the cytological map location 46B4. It is reported to have molecular function</span>: endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: response to DNA damage stimulus. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype <newline> ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR000426","proteasome core complex ; GO:0005839 | non-traceable author statement <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay <newline> proteasome core complex, alpha-subunit complex ; GO:0019773 | inferred from electronic annotation with InterPro:IPR000426","endopeptidase activity ; GO:0004175 | non-traceable author statement <newline> threonine-type endopeptidase activity ; GO:0004298 | inferred from electronic annotation with InterPro:IPR001353"]
[null,"FBgn0028686","Rpt3","Rpt3","The gene Rpt3 is referred to in FlyBase by the symbol Dmel\\Rpt3 (CG16916, FBgn0028686). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11019221..11020840. It has the cytological map location 10A6. There is experimental evidence that it has the molecular function</span>: endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: response to DNA damage stimulus; proteolysis. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","proteolysis ; GO:0006508 | inferred from direct assay AND inferred from sequence or structural similarity with HGNC_gene:PSMC4; HGNC:9551; OMIM:602707 AND inferred from sequence or structural similarity with SGD_LOCUS:RPT3; SGD:S0002802 <newline> response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype <newline> protein catabolic process ; GO:0030163 | inferred from electronic annotation with InterPro:IPR005937","proteasome regulatory particle, base subcomplex ; GO:0008540 | non-traceable author statement <newline> proteasome regulatory particle ; GO:0005838 | inferred from direct assay AND inferred from sequence or structural similarity with HGNC_gene:PSMC4; HGNC:9551; OMIM:602707 <newline> proteasome regulatory particle, base subcomplex ; GO:0008540 | inferred from sequence or structural similarity with SGD_LOCUS:RPT3; SGD:S0002802 <newline> male germ cell nucleus ; GO:0001673 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR005937","ATPase activity ; GO:0016887 | inferred from sequence or structural similarity with SGD_LOCUS:RPT3; SGD:S0002802 <newline> endopeptidase activity ; GO:0004175 | inferred from direct assay <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001270, InterPro:IPR003959, InterPro:IPR003960"]
[]
["Cell proliferation/ Apoptosis"]
[null,"FBgn0000472","diminutive","dm","The gene diminutive is referred to in FlyBase by the symbol Dmel\\dm (CG10798, FBgn0000472). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3267216..3280049. It has the cytological map location 3D2. There is experimental evidence that it has the molecular function</span>: transcription factor activity; protein binding; DNA binding. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: regulation of biological process; regulation of metabolic process; multicellular organismal development; regulation of growth; embryonic development; cell proliferation; embryonic development ending in birth or egg hatching; cell cycle; regulation of apoptosis; positive regulation of cellular biosynthetic process; anatomical structure development; cellular process; embryonic pattern specification; negative regulation of Notch signaling pathway. 55 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; peripheral nervous system; nervous system; external compound sense organ; female germline cyst; cell cycle; nucleus; thoracic segment; imaginal precursor; intracellular membrane-bounded organelle. It has one annotated transcript and one annotated polypeptide.","regulation of transcription, DNA-dependent ; GO:0006355 | inferred from direct assay <newline> cell proliferation ; GO:0008283 | inferred from expression pattern <newline> embryonic development ending in birth or egg hatching ; GO:0009792 | inferred from expression pattern <newline> positive regulation of cell growth ; GO:0030307 | traceable author statement <newline> positive regulation of growth ; GO:0045927 | traceable author statement <newline> regulation of cell size ; GO:0008361 | traceable author statement <newline> positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement <newline> DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype <newline> cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype <newline> regulation of organ growth ; GO:0046620 | inferred from mutant phenotype <newline> regulation of cell growth ; GO:0001558 | inferred from mutant phenotype <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | traceable author statement <newline> regulation of cell cycle ; GO:0051726 | traceable author statement <newline> positive regulation of transcription ; GO:0045941 | inferred from mutant phenotype <newline> neurogenesis ; GO:0022008 | inferred from genetic interaction with Egfr <newline> embryonic pattern specification ; GO:0009880 | inferred from genetic interaction with Egfr <newline> negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with N <newline> regulation of apoptosis ; GO:0042981 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:L00039 <newline> protein complex ; GO:0043234 | inferred from physical interaction with gro","DNA binding ; GO:0003677 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:L00039 <newline> protein binding ; GO:0005515 | inferred from physical interaction with lid <newline> protein binding ; GO:0005515 | inferred from physical interaction with gro"]
[null,"FBgn0000497","dachsous","ds","The gene dachsous is referred to in FlyBase by the symbol Dmel\\ds (CG17941, FBgn0000497). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:640021..714968. It has the cytological map location 21E2. There is experimental evidence that it has the molecular function</span>: cell adhesion molecule binding. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; establishment of planar polarity; sensory organ development; organ development; cell morphogenesis; epithelial cell differentiation; cell proliferation; biopolymer modification; cell adhesion. 60 alleles are reported. The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; thoracic segment; peripheral nervous system; external compound sense organ; nervous system; appendage segment; wing hair; dorsal thoracic disc; adult cuticle. It has one annotated transcript and one annotated polypeptide.","establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from mutant phenotype <newline> cell morphogenesis involved in differentiation ; GO:0000904 | inferred from mutant phenotype <newline> peptide cross-linking ; GO:0018149 | inferred from physical interaction with ft <newline> calcium-dependent cell-cell adhesion ; GO:0016339 | inferred from sequence or structural similarity <newline> establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype <newline> equator specification ; GO:0045317 | inferred from mutant phenotype <newline> establishment of epithelial cell apical/basal polarity ; GO:0045198 | inferred from mutant phenotype <newline> wing disc pattern formation ; GO:0035222 | inferred from mutant phenotype <newline> establishment of cell polarity ; GO:0030010 | inferred from mutant phenotype <newline> eye morphogenesis ; GO:0048592 | inferred from mutant phenotype <newline> imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> homophilic cell adhesion ; GO:0007156 | inferred from sequence or structural similarity <newline> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | traceable author statement <newline> ommatidial rotation ; GO:0016318 | traceable author statement <newline> establishment of tissue polarity ; GO:0007164 | non-traceable author statement <newline> establishment of planar polarity ; GO:0001736 | traceable author statement <newline> establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement <newline> calcium-dependent cell-cell adhesion ; GO:0016339 | inferred from sequence or structural similarity with UniProtKB:P33450 <newline> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype <newline> cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype <newline> homophilic cell adhesion ; GO:0007156 | inferred from electronic annotation with InterPro:IPR000233, InterPro:IPR002126","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> integral to plasma membrane ; GO:0005887 | inferred from sequence or structural similarity <newline> integral to membrane ; GO:0016021 | traceable author statement <newline> integral to plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with UniProtKB:P33450","cell adhesion molecule binding ; GO:0050839 | inferred from direct assay <newline> cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity <newline> receptor activity ; GO:0004872 | inferred from sequence or structural similarity <newline> signal transducer activity ; GO:0004871 | non-traceable author statement <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR000233, InterPro:IPR002126, InterPro:IPR015919"]
[null,"FBgn0000575","extra macrochaetae","emc","The gene extra macrochaetae is referred to in FlyBase by the symbol Dmel\\emc (CG1007, FBgn0000575). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:749406..753505. It has the cytological map location 61C9. There is experimental evidence that it has the molecular function</span>: transcription repressor activity; protein heterodimerization activity. There is experimental evidence for 19 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; sensory organ development; organ development; behavior; reproductive process in a multicellular organism; cell proliferation; negative regulation of molecular function; compound eye cone cell differentiation; embryonic development via the syncytial blastoderm; locomotory behavior; negative regulation of cellular biosynthetic process; reproductive developmental process; neuromuscular process; behavioral interaction between organisms. 94 alleles are reported. The phenotypes of these alleles are annotated with 42 unique terms, many of which group under: peripheral nervous system; organ system; nervous system; adult segment; external compound sense organ; adult mesothoracic segment; primordium; female germline cyst; midgut constriction; germ layer; Malpighian tubule. It has one annotated transcript and one annotated polypeptide.","negative regulation of transcription ; GO:0016481 | traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> sensory organ development ; GO:0007423 | traceable author statement <newline> sex determination ; GO:0007530 | inferred from genetic interaction with dpn, Sxl <newline> spermatid development ; GO:0007286 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from genetic interaction with Egfr AND inferred from genetic interaction with vn AND inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from genetic interaction with Egfr AND inferred from genetic interaction with vn AND inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from genetic interaction with bs AND inferred from genetic interaction with net AND inferred from genetic interaction with px AND inferred from mutant phenotype <newline> negative regulation of transcription ; GO:0016481 | non-traceable author statement <newline> sensory organ development ; GO:0007423 | non-traceable author statement <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | non-traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> sex determination, primary response to X:A ratio ; GO:0007541 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype <newline> bristle morphogenesis ; GO:0008407 | traceable author statement <newline> R8 cell fate commitment ; GO:0007460 | non-traceable author statement <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> midgut development ; GO:0007494 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> brain morphogenesis ; GO:0048854 | inferred from mutant phenotype <newline> startle response ; GO:0001964 | inferred from mutant phenotype <newline> locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype <newline> R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype <newline> compound eye cone cell differentiation ; GO:0042675 | inferred from mutant phenotype <newline> progression of morphogenetic furrow during compound eye morphogenesis ; GO:0007458 | inferred from mutant phenotype <newline> R3/R4 cell differentiation ; GO:0048056 | inferred from mutant phenotype <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype <newline> negative regulation of DNA binding ; GO:0043392 | inferred from direct assay <newline> negative regulation of transcription ; GO:0016481 | inferred from direct assay","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P41137 <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from direct assay","transcription corepressor activity ; GO:0003714 | inferred from sequence or structural similarity with UniProtKB:P41137 <newline> protein binding ; GO:0005515 | non-traceable author statement <newline> transcription corepressor activity ; GO:0003714 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | inferred from direct assay <newline> protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da inferred from physical interaction with ac inferred from physical interaction with sc inferred from physical interaction with l(1)sc <newline> protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da"]
[null,"FBgn0001235","homothorax","hth","The gene homothorax is referred to in FlyBase by the symbol Dmel\\hth (CG17117, FBgn0001235). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:6335569..6464386. It has the cytological map location 86C1-86C3. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of gene-specific transcription from RNA polymerase II promoter; compound eye development; specification of segmental identity, antennal segment; specification of segmental identity, head; segmentation; compound eye photoreceptor fate commitment; brain development; imaginal disc-derived wing morphogenesis; haltere morphogenesis; imaginal disc-derived leg morphogenesis. 64 alleles are reported. The phenotypes of these alleles are annotated with 63 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; thoracic segment; external compound sense organ; appendage segment; adult mesothoracic segment; embryonic segment; embryonic nervous system; organ system; antennal segment. It has 8 annotated transcripts and 8 annotated polypeptides.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> brain development ; GO:0007420 | inferred from mutant phenotype <newline> proximal/distal pattern formation ; GO:0009954 | traceable author statement <newline> specification of organ identity ; GO:0010092 | traceable author statement <newline> compound eye photoreceptor fate commitment ; GO:0001752 | inferred from mutant phenotype <newline> leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype <newline> specification of segmental identity, antennal segment ; GO:0007383 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype <newline> haltere morphogenesis ; GO:0048735 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> transcription factor activity ; GO:0003700 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356"]
[null,"FBgn0003396","schnurri","shn","The gene schnurri is referred to in FlyBase by the symbol Dmel\\shn (CG7734, FBgn0003396). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7061325..7104918. It has the cytological map location 47D6-47D7. There is experimental evidence that it has the molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: olfactory learning; ectoderm development; learning or memory; cell proliferation; imaginal disc-derived wing vein morphogenesis; wing disc anterior/posterior pattern formation; wing disc dorsal/ventral pattern formation; imaginal disc-derived wing morphogenesis; midgut development. 108 alleles are reported. The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; peripheral nervous system; adult segment; embryonic nervous system; adult mesothoracic segment; nervous system; external compound sense organ; primordium; embryonic peripheral nervous system; embryonic head; midgut constriction; podocyte; organ system subdivision; multi-cell-component structure; spiracle. It has 4 annotated transcripts and 4 annotated polypeptides.","ectoderm development ; GO:0007398 | inferred from mutant phenotype <newline> midgut development ; GO:0007494 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from mutant phenotype <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from genetic interaction with dpp AND inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> learning or memory ; GO:0007611 | inferred from mutant phenotype <newline> olfactory learning ; GO:0008355 | inferred from mutant phenotype <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement <newline> negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement <newline> compound eye morphogenesis ; GO:0001745 | non-traceable author statement <newline> negative regulation of cell proliferation ; GO:0008285 | non-traceable author statement <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap","nucleus ; GO:0005634 | non-traceable author statement <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:X51435; protein_id:CAA35798.1 <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from mutant phenotype <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003604, InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0003997","Wrinkled","W","The gene Wrinkled is referred to in FlyBase by the symbol Dmel\\W (CG5123, FBgn0003997). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:18160842..18178737. It has the cytological map location 75C1. Its molecular function is unknown. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: anatomical structure development; positive regulation of programmed cell death; programmed cell death; regulation of biological process; gland morphogenesis; cell death; regulation of apoptosis; response to light stimulus; response to radiation; entrainment of circadian clock. 63 alleles are reported. The phenotypes of these alleles are annotated with 35 unique terms, many of which group under: nervous system; peripheral nervous system; organ system; external compound sense organ; adult segment; embryonic nervous system; cephalopharyngeal skeleton; antennal segment; multi-cell-component structure; larval head segment; imaginal precursor. It has one annotated transcript and one annotated polypeptide.","response to red light ; GO:0010114 | inferred from mutant phenotype <newline> entrainment of circadian clock by photoperiod ; GO:0043153 | inferred from mutant phenotype <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> instar larval or pupal development ; GO:0002165 | inferred from mutant phenotype <newline> programmed cell death ; GO:0012501 | inferred from mutant phenotype <newline> programmed cell death ; GO:0012501 | inferred from genetic interaction with rpr AND inferred from mutant phenotype <newline> induction of apoptosis ; GO:0006917 | traceable author statement <newline> induction of apoptosis ; GO:0006917 | inferred from genetic interaction with Dcp-1 AND inferred from genetic interaction with th <newline> salivary gland cell autophagic cell death ; GO:0035071 | non-traceable author statement <newline> ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | inferred from expression pattern <newline> nurse cell apoptosis ; GO:0045476 | NOT traceable author statement <newline> ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | non-traceable author statement <newline> embryonic development via the syncytial blastoderm ; GO:0001700 | traceable author statement <newline> compound eye retinal cell programmed cell death ; GO:0046667 | traceable author statement <newline> programmed cell death ; GO:0012501 | traceable author statement <newline> regulation of retinal cell programmed cell death ; GO:0046668 | non-traceable author statement <newline> larval midgut cell programmed cell death ; GO:0035096 | non-traceable author statement <newline> apoptosis ; GO:0006915 | non-traceable author statement <newline> protein ubiquitination ; GO:0016567 | traceable author statement <newline> regulation of proteolysis ; GO:0030162 | traceable author statement <newline> regulation of organ growth ; GO:0046620 | inferred from mutant phenotype <newline> apoptosis ; GO:0006915 | traceable author statement <newline> induction of apoptosis ; GO:0006917 | inferred from mutant phenotype <newline> larval midgut cell programmed cell death ; GO:0035096 | inferred from genetic interaction with rpr <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from genetic interaction with rpr AND inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> cell death ; GO:0008219 | inferred from mutant phenotype <newline> head involution ; GO:0008258 | non-traceable author statement <newline> induction of apoptosis ; GO:0006917 | non-traceable author statement <newline> antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype <newline> positive regulation of apoptosis ; GO:0043065 | inferred from mutant phenotype","-","-"]
[null,"FBgn0004924","Topoisomerase 1","Top1","The gene Topoisomerase 1 is referred to in FlyBase by the symbol Dmel\\Top1 (CG6146, FBgn0004924). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15213525..15222062. It has the cytological map location 13B6. There is experimental evidence that it has the molecular function</span>: DNA topoisomerase activity; DNA topoisomerase type I activity. There is experimental evidence that it is involved in the biological process</span>: instar larval development; cell proliferation; chromosome segregation; DNA topological change; multicellular organismal development; oogenesis; embryonic development; chromosome condensation. 32 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; anatomical structure; female germline cyst; nervous system; germarium; adult brain; egg; cell cycle; imaginal precursor; peripheral nervous system; adult segment. It has 3 annotated transcripts and 3 annotated polypeptides.","embryonic development ; GO:0009790 | inferred from mutant phenotype <newline> instar larval development ; GO:0002168 | inferred from mutant phenotype <newline> multicellular organismal development ; GO:0007275 | inferred from mutant phenotype <newline> DNA topological change ; GO:0006265 | inferred from direct assay <newline> chromosome condensation ; GO:0030261 | inferred from mutant phenotype <newline> chromosome segregation ; GO:0007059 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> DNA unwinding involved in replication ; GO:0006268 | inferred from electronic annotation with InterPro:IPR013030, InterPro:IPR014711, InterPro:IPR014727","cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> polytene chromosome puff ; GO:0005703 | inferred from direct assay <newline> DNA-directed RNA polymerase II, core complex ; GO:0005665 | colocalizes_with inferred from direct assay <newline> nucleolus ; GO:0005730 | inferred from direct assay <newline> nuclear euchromatin ; GO:0005719 | inferred from direct assay <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","DNA topoisomerase type I activity ; GO:0003917 | inferred from sequence or structural similarity with UniProtKB:Q7YR26 <newline> DNA topoisomerase type I activity ; GO:0003917 | non-traceable author statement <newline> DNA topoisomerase type I activity ; GO:0003917 | inferred from direct assay <newline> DNA topoisomerase activity ; GO:0003916 | inferred from direct assay <newline> DNA topoisomerase (ATP-hydrolyzing) activity ; GO:0003918 | inferred from electronic annotation with InterPro:IPR013500"]
[null,"FBgn0005771","no ocelli","noc","The gene no ocelli is referred to in FlyBase by the symbol Dmel\\noc (CG4491, FBgn0005771). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:14490862..14494019. It has the cytological map location 35B2. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior; eye-antennal disc development; cell proliferation; open tracheal system development. 55 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: peripheral nervous system; nervous system; organ system; adult segment; embryonic/larval tracheal system; integumentary plate; adult mesothoracic segment; embryonic dorsal branch; adult brain; adult external prothorax; embryonic ganglionic branch; postalar bristle. It has one annotated transcript and one annotated polypeptide.","regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from genetic interaction with elB <newline> eye-antennal disc development ; GO:0035214 | inferred from genetic interaction with elB <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0010300","brain tumor","brat","The gene brain tumor is referred to in FlyBase by the symbol Dmel\\brat (CG10719, FBgn0010300). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:19133806..19172572. It has the cytological map location 37C1-37C6. There is experimental evidence that it has the molecular function</span>: protein binding; translation repressor activity. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; cell division; cellular macromolecule metabolic process; stem cell differentiation; regulation of biological process; transport; ncRNA metabolic process; neuroblast fate commitment; regionalization; biopolymer biosynthetic process; reproductive process in a multicellular organism; regulation of neurogenesis; neuron differentiation; regulation of metabolic process. 100 alleles are reported. The phenotypes of these alleles are annotated with: eye; neuron; 1st posterior cell; embryonic abdomen; adult thorax; embryonic epidermis; imaginal disc; embryonic/larval brain; ganglion mother cell; embryonic abdominal segment. It has 3 annotated transcripts and 3 annotated polypeptides.","rRNA metabolic process ; GO:0016072 | inferred from mutant phenotype <newline> rRNA transcription ; GO:0009303 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype <newline> brain development ; GO:0007420 | inferred from mutant phenotype <newline> asymmetric cell division ; GO:0008356 | inferred from mutant phenotype <newline> negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype <newline> ganglion mother cell fate determination ; GO:0007402 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | non-traceable author statement <newline> regulation of translation ; GO:0006417 | inferred from mutant phenotype <newline> regulation of translation ; GO:0006417 | traceable author statement <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> asymmetric neuroblast division resulting in ganglion mother cell formation ; GO:0055060 | inferred from mutant phenotype <newline> neuron differentiation ; GO:0030182 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay <newline> basal cortex ; GO:0045180 | colocalizes_with inferred from direct assay <newline> apical cortex ; GO:0045179 | colocalizes_with inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with nos <newline> translation repressor activity ; GO:0030371 | inferred from mutant phenotype <newline> translation regulator activity ; GO:0045182 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with 4EHP <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000315"]
[null,"FBgn0010379","Akt1","Akt1","The gene Akt1 is referred to in FlyBase by the symbol Dmel\\Akt1 (CG4006, FBgn0010379). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11924938..11930239. It has the cytological map location 89B3. There is experimental evidence that it has the molecular function</span>: protein serine/threonine kinase activity; protein kinase activity. There is experimental evidence for 13 unique biological process</span> terms, many of which group under: regulation of biological process; regulation of developmental process; anatomical structure development; regulation of anatomical structure size; positive regulation of biological process; GO:0023034; biopolymer modification; lipid storage; regulation of apoptosis; regulation of neurogenesis; response to hormone stimulus. 30 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; organ system; external compound sense organ; adult mesothoracic segment; peripheral nervous system; thoracic segment; nervous system; wing hair; dorsal thoracic disc; synapse; embryonic trachea. It has 3 annotated transcripts and 3 annotated polypeptides.","anti-apoptosis ; GO:0006916 | inferred from mutant phenotype <newline> positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype <newline> positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement <newline> positive regulation of cell growth ; GO:0030307 | traceable author statement <newline> regulation of organ growth ; GO:0046620 | non-traceable author statement <newline> positive regulation of cell size ; GO:0045793 | traceable author statement <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> positive regulation of cell size ; GO:0045793 | non-traceable author statement <newline> positive regulation of organ growth ; GO:0046622 | non-traceable author statement <newline> insulin receptor signaling pathway ; GO:0008286 | non-traceable author statement <newline> positive regulation of cell growth ; GO:0030307 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> positive regulation of organ growth ; GO:0046622 | traceable author statement <newline> insulin receptor signaling pathway ; GO:0008286 | traceable author statement <newline> regulation of multicellular organism growth ; GO:0040014 | non-traceable author statement <newline> regulation of cell size ; GO:0008361 | non-traceable author statement <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from genetic interaction with Pi3K21B <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> regulation of protein import into nucleus ; GO:0042306 | traceable author statement <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> lipid storage ; GO:0019915 | inferred from genetic interaction with Pten <newline> positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype <newline> insulin receptor signaling pathway ; GO:0008286 | inferred from genetic interaction with UniProtKB:P91634 <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay <newline> regulation of dendrite development ; GO:0050773 | inferred from mutant phenotype <newline> regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype <newline> positive regulation of organ growth ; GO:0046622 | inferred from mutant phenotype <newline> intracellular signaling pathway ; GO:0023034 | inferred from genetic interaction with UniProtKB:P91634","plasma membrane ; GO:0005886 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> cell surface ; GO:0009986 | inferred from direct assay","protein kinase activity ; GO:0004672 | inferred from direct assay <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from mutant phenotype <newline> protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement <newline> phosphoinositide binding ; GO:0035091 | non-traceable author statement <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR015744, InterPro:IPR017441, InterPro:IPR017442, InterPro:IPR017892"]
[null,"FBgn0011766","E2F transcription factor","E2f","The gene E2F transcription factor is referred to in FlyBase by the symbol Dmel\\E2f (CG6376, FBgn0011766). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17446026..17486127. It has the cytological map location 93E9-93F1. There is experimental evidence that it has the molecular function</span>: protein binding; RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of gene expression; cellular process; dendrite morphogenesis; neuron development; positive regulation of nurse cell apoptosis; muscle tissue development; antimicrobial humoral response; regulation of cell cycle; DNA endoreduplication. 70 alleles are reported. The phenotypes of these alleles are annotated with 31 unique terms, many of which group under: organ system; peripheral nervous system; nervous system; external compound sense organ; female germline cyst; egg; imaginal precursor; adult segment; cell part; primordium; adult mesothoracic segment. It has 3 annotated transcripts and 3 annotated polypeptides.","positive regulation of cell proliferation ; GO:0008284 | non-traceable author statement <newline> positive regulation of nurse cell apoptosis ; GO:0045850 | inferred from mutant phenotype <newline> DNA endoreduplication ; GO:0042023 | inferred from genetic interaction with CycE AND inferred from mutant phenotype <newline> eggshell chorion gene amplification ; GO:0007307 | traceable author statement <newline> G1/S transition of mitotic cell cycle ; GO:0000082 | traceable author statement <newline> imaginal disc development ; GO:0007444 | traceable author statement <newline> nurse cell apoptosis ; GO:0045476 | traceable author statement <newline> positive regulation of transcription ; GO:0045941 | traceable author statement <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> regulation of transcription involved in G1/S-phase of mitotic cell cycle ; GO:0000083 | non-traceable author statement <newline> growth ; GO:0040007 | non-traceable author statement <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | non-traceable author statement <newline> positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> muscle tissue development ; GO:0060537 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003316","nucleus ; GO:0005634 | inferred from direct assay <newline> Rb-E2F complex ; GO:0035189 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","DNA binding ; GO:0003677 | inferred from direct assay <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with Rbf <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription activator activity ; GO:0016563 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with dom inferred from physical interaction with l(3)mbt <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR003316"]
[null,"FBgn0013263","Trithorax-like","Trl","The gene Trithorax-like is referred to in FlyBase by the symbol Dmel\\Trl (CG33261, FBgn0013263). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14741029..14754149. It has the cytological map location 70F4. There is experimental evidence that it has the molecular function</span>: protein binding; specific RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: cellular process; dosage compensation; nuclear division; syncytial blastoderm mitotic cell cycle; imaginal disc-derived wing morphogenesis; protein oligomerization. 68 alleles are reported. The phenotypes of these alleles are annotated with: eye; abdominal segment 6; egg; sex comb; micropyle; wing; imaginal disc; egg chamber; chromatin; denticle belt. It has 9 annotated transcripts and 9 annotated polypeptides.","nuclear division ; GO:0000280 | inferred from mutant phenotype <newline> syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | non-traceable author statement <newline> chromatin organization ; GO:0006325 | non-traceable author statement <newline> dosage compensation ; GO:0007549 | inferred from mutant phenotype <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> positive regulation of transcription, DNA-dependent ; GO:0045893 | traceable author statement <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> protein oligomerization ; GO:0051259 | inferred from direct assay","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> centromeric heterochromatin ; GO:0005721 | inferred from direct assay AND traceable author statement <newline> chromatin ; GO:0000785 | non-traceable author statement","DNA binding ; GO:0003677 | non-traceable author statement <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from mutant phenotype <newline> protein binding ; GO:0005515 | inferred from physical interaction with Ssrp <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P17789 <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P41046 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0036666","tumor suppressor protein 101","TSG101","The gene tumor suppressor protein 101 is referred to in FlyBase by the symbol Dmel\\TSG101 (CG9712, FBgn0036666). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:16835399..16837686. It has the cytological map location 73D1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: negative regulation of growth; negative regulation of growth or development of symbiont in host; regulation of JAK-STAT cascade; negative regulation of imaginal disc growth; maintenance of apical/basal cell polarity. 7 alleles are reported. The phenotypes of these alleles are annotated with: yolk granule; oocyte; vesicle. It has one annotated transcript and one annotated polypeptide.","negative regulation of growth ; GO:0045926 | inferred from mutant phenotype <newline> regulation of JAK-STAT cascade ; GO:0046425 | inferred from mutant phenotype <newline> maintenance of apical/basal cell polarity ; GO:0035090 | inferred from mutant phenotype <newline> negative regulation of imaginal disc growth ; GO:0045571 | inferred from mutant phenotype <newline> negative regulation of growth or development of symbiont in host (obsolete GO:0033667) ; GO:0033667 | inferred from mutant phenotype <newline> regulation of protein metabolic process ; GO:0051246 | inferred from electronic annotation with InterPro:IPR000608 <newline> post-translational protein modification ; GO:0043687 | inferred from electronic annotation with InterPro:IPR000608 <newline> protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR008883","-","protein binding ; GO:0005515 | inferred from physical interaction with Vps28 <newline> small conjugating protein ligase activity ; GO:0019787 | inferred from electronic annotation with InterPro:IPR000608"]
[null,"FBgn0041094","scylla","scyl","The gene scylla is referred to in FlyBase by the symbol Dmel\\scyl (CG7590, FBgn0041094). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:11245410..11248343. It has the cytological map location 68B4-68C1. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: negative regulation of growth; response to DNA damage stimulus; head involution; cell death. 17 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","negative regulation of growth ; GO:0045926 | inferred from genetic interaction with chrb <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> cell death ; GO:0008219 | inferred from mutant phenotype <newline> response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype <newline> negative regulation of signal transduction ; GO:0009968 | inferred from electronic annotation with InterPro:IPR012918","cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR012918","molecular_function ; GO:0003674 | no biological data available"]
[null,"FBgn0259211","grainy head","grh","The gene grainy head is referred to in FlyBase by the symbol Dmel\\grh (CG42311, FBgn0259211). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13690294..13729118. It has the cytological map location 54E10-54F1. There is experimental evidence that it has the molecular function</span>: specific RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; nervous system development; tracheal outgrowth, open tracheal system; regulation of cell proliferation; open tracheal system development; regulation of tube length, open tracheal system; plasma membrane organization; chitin-based embryonic cuticle biosynthetic process. 70 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; embryonic/larval tracheal system; somatic stem cell; cephalopharyngeal skeleton; portion of tissue; cuticle; adult segment; larval abdominal segment; adult mesothoracic segment; developing anatomical structure. It has 7 annotated transcripts and 7 annotated polypeptides.","plasma membrane organization ; GO:0007009 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype <newline> tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from expression pattern <newline> ganglion mother cell fate determination ; GO:0007402 | traceable author statement <newline> ventral cord development ; GO:0007419 | non-traceable author statement <newline> nervous system development ; GO:0007399 | inferred from mutant phenotype <newline> regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype <newline> cellular membrane organization ; GO:0016044 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> primary branching, open tracheal system ; GO:0007428 | traceable author statement <newline> regulation of tube architecture, open tracheal system ; GO:0035152 | traceable author statement","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","DNA binding ; GO:0003677 | inferred from direct assay <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from direct assay <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement"]
[null,"FBgn0260635","thread","th","The gene thread is referred to in FlyBase by the symbol Dmel\\th (CG12284, FBgn0260635). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:16031505..16043755. It has the cytological map location 72C1-72D1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: apoptosis; spermatid nucleus differentiation; anti-apoptosis; border follicle cell migration; sensory organ development; cellular process; negative regulation of apoptosis; antennal morphogenesis; positive regulation of protein ubiquitination. 167 alleles are reported. The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: organ system; anatomical structure; embryonic segment; embryonic nervous system; female germline cyst; antennal segment; embryonic head; nervous system; peripheral nervous system; adult segment. It has 3 annotated transcripts and 3 annotated polypeptides.","anti-apoptosis ; GO:0006916 | inferred from direct assay <newline> anti-apoptosis ; GO:0006916 | inferred from genetic interaction with W AND inferred from genetic interaction with rpr <newline> apoptosis ; GO:0006915 | inferred from physical interaction with W AND inferred from physical interaction with rpr <newline> negative regulation of caspase activity ; GO:0043154 | traceable author statement <newline> anti-apoptosis ; GO:0006916 | non-traceable author statement <newline> anti-apoptosis ; GO:0006916 | traceable author statement <newline> apoptosis ; GO:0006915 | traceable author statement <newline> negative regulation of apoptosis ; GO:0043066 | traceable author statement <newline> protein monoubiquitination ; GO:0006513 | traceable author statement <newline> multicellular organismal development ; GO:0007275 | traceable author statement <newline> protein ubiquitination during ubiquitin-dependent protein catabolic process ; GO:0042787 | traceable author statement <newline> apoptosis ; GO:0006915 | non-traceable author statement <newline> spermatid nucleus differentiation ; GO:0007289 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Rac1 AND inferred from mutant phenotype <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype AND inferred from sequence or structural similarity <newline> negative regulation of apoptosis ; GO:0043066 | inferred from sequence or structural similarity with UniProtKB:P98170 <newline> germ cell migration ; GO:0008354 | traceable author statement <newline> antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> positive regulation of protein ubiquitination ; GO:0031398 | inferred from direct assay","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001370","ubiquitin-protein ligase activity ; GO:0004842 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with ik2 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841"]
[null,"FBgn0262127","kibra ortholog","kibra","The gene kibra ortholog is referred to in FlyBase by the symbol Dmel\\kibra (CG33967, FBgn0262127). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: regulation of hippo signaling pathway; compound eye morphogenesis. 46 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; eye. It has one annotated transcript and one annotated polypeptide. Protein features are: C2 calcium-dependent membrane targeting; C2 calcium/lipid-binding domain, CaLB; WW/Rsp5/WWP. Gene sequence location is 3R:10524252..10549978.","regulation of hippo signaling cascade ; GO:0035330 | inferred from genetic interaction with hpo inferred from genetic interaction with Mer inferred from genetic interaction with ex <newline> regulation of hippo signaling cascade ; GO:0035330 | inferred from genetic interaction with hpo inferred from genetic interaction with yki <newline> regulation of hippo signaling cascade ; GO:0035330 | inferred from genetic interaction with ex inferred from genetic interaction with Mer inferred from genetic interaction with sav inferred from genetic interaction with hpo <newline> compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with crb","apical part of cell ; GO:0045177 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with Mer inferred from physical interaction with ex inferred from physical interaction with wts <newline> protein binding ; GO:0005515 | inferred from physical interaction with Mer <newline> protein binding ; GO:0005515 | inferred from physical interaction with sav"]
[null,"FBgn0010709","Autophagy-specific gene 6","Atg6","The gene Autophagy-specific gene 6 is referred to in FlyBase by the symbol Dmel\\Atg6 (CG5429, FBgn0010709). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: autophagic cell death; salivary gland cell autophagic cell death. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Autophagy-related protein 6. Gene sequence location is 3R:19874893..19876735.","autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> autophagy ; GO:0006914 | inferred from electronic annotation with InterPro:IPR007243","-","-"]
[null,"FBgn0030457","-","CG12096","This gene is referred to in FlyBase by the symbol Dmel\\CG12096 (FBgn0030457). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. There is experimental evidence that it is involved in the biological process</span>: response to DNA damage stimulus. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: 26S proteasome non-ATPase regulatory subunit 5; Armadillo-type fold. Gene sequence location is X:13053739..13055732.","response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype","-","binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR016024"]
[null,"FBgn0003209","raw","raw","The gene raw is referred to in FlyBase by the symbol Dmel\\raw (CG12437, FBgn0003209). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence for 13 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; digestive tract development; gland morphogenesis; biological regulation; organ development; programmed cell death; multicellular organismal process; embryonic hindgut morphogenesis; embryonic development via the syncytial blastoderm. 31 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; anatomical structure; cuticle; nervous system; integumentary system; embryonic nervous system; Malpighian tubule; cuticular specialization; extended germ band embryo; embryonic head; midgut constriction; axon. It has 3 annotated transcripts and 3 annotated polypeptides. Gene sequence location is 2L:8709880..8740660.","autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype <newline> central nervous system development ; GO:0007417 | inferred from mutant phenotype <newline> regulation of Malpighian tubule diameter ; GO:0035297 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> ectodermal digestive tract morphogenesis ; GO:0048567 | inferred from mutant phenotype <newline> germ-band shortening ; GO:0007390 | inferred from mutant phenotype <newline> morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> regulation of JNK cascade ; GO:0046328 | non-traceable author statement <newline> hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype <newline> protein localization ; GO:0008104 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> dorsal closure, elongation of leading edge cells ; GO:0007394 | traceable author statement","-","-"]
[null,"FBgn0010488","NAT1","NAT1","The gene NAT1 is referred to in FlyBase by the symbol Dmel\\NAT1 (CG3845, FBgn0010488). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: translation initiation factor activity. There is experimental evidence that it is involved in the biological process</span>: autophagic cell death; salivary gland cell autophagic cell death. 9 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Armadillo-type fold; Initiation factor eIF-4 gamma, MA3; MIF4-like, type 1/2/3; MIF4G-like, type 3; eIF4-gamma/eIF5/eIF2-epsilon. Gene sequence location is 2R:8803502..8810745.","autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> RNA metabolic process ; GO:0016070 | inferred from electronic annotation with InterPro:IPR003890, InterPro:IPR016021","mRNA cap binding complex ; GO:0005845 | inferred from sequence or structural similarity with NCBI_gi:4503539","translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with NCBI_gi:4503539"]
[null,"FBgn0010501","Death caspase-1","Dcp-1","The gene Death caspase-1 is referred to in FlyBase by the symbol Dmel\\Dcp-1 (CG5370, FBgn0010501). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: cysteine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: apoptosis; ovarian nurse cell to oocyte transport; cleavage of lamin; actin cytoskeleton organization; embryonic development; autophagic cell death; developmental programmed cell death; salivary gland cell autophagic cell death. 38 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; eye; embryonic/larval digestive system; gonad; trachea; imaginal disc; outer photoreceptor cell; egg chamber; melanotic mass; pigment cell. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase C14, ICE, catalytic subunit p20; Peptidase C14, ICE, catalytic subunit p20, active site; Peptidase C14, caspase catalytic; Peptidase C14, caspase non-catalytic subunit p10; Peptidase C14, caspase precursor p45; Peptidase C14, caspase precursor p45, core. Gene sequence location is 2R:19438838..19441079.","apoptosis ; GO:0006915 | inferred from direct assay <newline> embryo development ; GO:0009790 | inferred from mutant phenotype <newline> actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype <newline> cleavage of lamin ; GO:0006922 | inferred from mutant phenotype <newline> ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype <newline> actin filament organization ; GO:0007015 | traceable author statement <newline> cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | traceable author statement <newline> nurse cell apoptosis ; GO:0045476 | traceable author statement <newline> apoptosis ; GO:0006915 | non-traceable author statement <newline> apoptosis ; GO:0006915 | traceable author statement <newline> proteolysis ; GO:0006508 | traceable author statement <newline> multicellular organismal development ; GO:0007275 | traceable author statement <newline> ovarian nurse cell to oocyte transport ; GO:0007300 | traceable author statement <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> apoptosis ; GO:0006915 | inferred from mutant phenotype <newline> developmental programmed cell death ; GO:0010623 | inferred from mutant phenotype","caspase complex ; GO:0008303 | non-traceable author statement","cysteine-type endopeptidase activity ; GO:0004197 | inferred from direct assay <newline> cysteine-type endopeptidase activity ; GO:0004197 | inferred from direct assay AND inferred from sequence or structural similarity <newline> cysteine-type endopeptidase activity ; GO:0004197 | traceable author statement <newline> cysteine-type endopeptidase activity ; GO:0004197 | non-traceable author statement <newline> cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity"]
[null,"FBgn0010488","NAT1","NAT1","The gene NAT1 is referred to in FlyBase by the symbol Dmel\\NAT1 (CG3845, FBgn0010488). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8803502..8810745. It has the cytological map location 49E1. Based on sequence similarity, it is predicted to have molecular function</span>: translation initiation factor activity. There is experimental evidence that it is involved in the biological process</span>: autophagic cell death; salivary gland cell autophagic cell death. 8 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> RNA metabolic process ; GO:0016070 | inferred from electronic annotation with InterPro:IPR003890, InterPro:IPR016021","mRNA cap binding complex ; GO:0005845 | inferred from sequence or structural similarity with NCBI_gi:4503539","translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with NCBI_gi:4503539 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR003890, InterPro:IPR016021"]
[null,"FBgn0259236","comm3","comm3","The gene comm3 is referred to in FlyBase by the symbol Dmel\\comm3 (CG42334, FBgn0259236). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: autophagic cell death; salivary gland cell autophagic cell death. 13 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Gene sequence location is 3L:15606284..15640837.","autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern","-","-"]
[]
["Cell shape"]
[null,"FBgn0000472","diminutive","dm","The gene diminutive is referred to in FlyBase by the symbol Dmel\\dm (CG10798, FBgn0000472). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3267216..3280049. It has the cytological map location 3D2. There is experimental evidence that it has the molecular function</span>: transcription factor activity; protein binding; DNA binding. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: regulation of biological process; regulation of metabolic process; multicellular organismal development; regulation of growth; embryonic development; cell proliferation; embryonic development ending in birth or egg hatching; cell cycle; regulation of apoptosis; positive regulation of cellular biosynthetic process; anatomical structure development; cellular process; embryonic pattern specification; negative regulation of Notch signaling pathway. 55 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; peripheral nervous system; nervous system; external compound sense organ; female germline cyst; cell cycle; nucleus; thoracic segment; imaginal precursor; intracellular membrane-bounded organelle. It has one annotated transcript and one annotated polypeptide.","regulation of transcription, DNA-dependent ; GO:0006355 | inferred from direct assay <newline> cell proliferation ; GO:0008283 | inferred from expression pattern <newline> embryonic development ending in birth or egg hatching ; GO:0009792 | inferred from expression pattern <newline> positive regulation of cell growth ; GO:0030307 | traceable author statement <newline> positive regulation of growth ; GO:0045927 | traceable author statement <newline> regulation of cell size ; GO:0008361 | traceable author statement <newline> positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement <newline> DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype <newline> cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype <newline> regulation of organ growth ; GO:0046620 | inferred from mutant phenotype <newline> regulation of cell growth ; GO:0001558 | inferred from mutant phenotype <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | traceable author statement <newline> regulation of cell cycle ; GO:0051726 | traceable author statement <newline> positive regulation of transcription ; GO:0045941 | inferred from mutant phenotype <newline> neurogenesis ; GO:0022008 | inferred from genetic interaction with Egfr <newline> embryonic pattern specification ; GO:0009880 | inferred from genetic interaction with Egfr <newline> negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with N <newline> regulation of apoptosis ; GO:0042981 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:L00039 <newline> protein complex ; GO:0043234 | inferred from physical interaction with gro","DNA binding ; GO:0003677 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:L00039 <newline> protein binding ; GO:0005515 | inferred from physical interaction with lid <newline> protein binding ; GO:0005515 | inferred from physical interaction with gro"]
[null,"FBgn0003870","tramtrack","ttk","The gene tramtrack is referred to in FlyBase by the symbol Dmel\\ttk (CG1856, FBgn0003870). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27539591..27561114. It has the cytological map location 100D1. There is experimental evidence that it has the molecular function</span>: protein binding; specific transcriptional repressor activity; chromatin binding; protein homodimerization activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; inter-male aggressive behavior; startle response; brain morphogenesis; dendrite morphogenesis; neuron development; ovarian follicle cell development; negative regulation of transcription, DNA-dependent; dorsal appendage formation; locomotion involved in locomotory behavior. 153 alleles are reported. The phenotypes of these alleles are annotated with 70 unique terms, many of which group under: peripheral nervous system; nervous system; external compound sense organ; adult segment; embryonic nervous system; multi-cell-component structure; adult mesothoracic segment; embryonic glial cell; imaginal precursor; larval abdominal segment 5. It has 8 annotated transcripts and 8 annotated polypeptides.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> R7 cell development ; GO:0045467 | traceable author statement <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> cell fate determination ; GO:0001709 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> brain morphogenesis ; GO:0048854 | inferred from mutant phenotype <newline> startle response ; GO:0001964 | inferred from mutant phenotype <newline> locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | inferred from direct assay <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype","polytene chromosome ; GO:0005700 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with CoRest <newline> chromatin binding ; GO:0003682 | inferred from direct assay <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> protein homodimerization activity ; GO:0042803 | inferred from physical interaction with UniProtKB:P17789 <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q08605 <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR017956 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0004449","Tenascin major","Ten-m","The gene Tenascin major is referred to in FlyBase by the symbol Dmel\\Ten-m (CG5723, FBgn0004449). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:22286132..22400987. It has the cytological map location 79D4-79E3. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; R7 cell development; bristle development; compound eye photoreceptor development; periodic partitioning by pair rule gene; compound eye corneal lens development; cell adhesion; compound eye morphogenesis. 47 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; abdominal ventral denticle belt; cuticle; larval abdominal segment; external compound sense organ; nervous system; peripheral nervous system; thoracic segment; metathoracic ventral denticle belt; embryonic head; embryonic nervous system; abdominal 5 ventral denticle belt. It has 2 annotated transcripts and 2 annotated polypeptides.","cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> cell adhesion ; GO:0007155 | inferred from sequence or structural similarity with EMBL:AB025410 <newline> periodic partitioning by pair rule gene ; GO:0007366 | inferred from mutant phenotype <newline> compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype <newline> R7 cell development ; GO:0045467 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> bristle development ; GO:0022416 | inferred from mutant phenotype <newline> compound eye corneal lens development ; GO:0048058 | inferred from mutant phenotype","proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity <newline> integral to plasma membrane ; GO:0005887 | inferred from direct assay <newline> proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with EMBL:AB025410","-"]
[null,"FBgn0004657","myospheroid","mys","The gene myospheroid is referred to in FlyBase by the symbol Dmel\\mys (CG1560, FBgn0004657). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7955680..7964270. It has the cytological map location 7D5. It is reported to have molecular function</span>: cell adhesion molecule binding; receptor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; central nervous system development; germ-line stem cell maintenance; determination of adult lifespan; axon guidance; hemocyte migration; cell adhesion; muscle organ development; maintenance of epithelial integrity, open tracheal system; substrate-bound cell migration, cell extension. 141 alleles are reported. The phenotypes of these alleles are annotated with 55 unique terms, many of which group under: organ system; hypodermal muscle of larval abdomen; adult segment; primordium; nervous system; larval abdominal segment 5; adult mesothoracic segment; larval abdominal segment; extended germ band embryo; abdominal 7 longitudinal muscle; external compound sense organ. It has one annotated transcript and one annotated polypeptide.","central nervous system development ; GO:0007417 | inferred from mutant phenotype <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> cell migration ; GO:0016477 | traceable author statement <newline> midgut development ; GO:0007494 | traceable author statement <newline> muscle attachment ; GO:0016203 | traceable author statement <newline> calcium-dependent cell-cell adhesion ; GO:0016339 | traceable author statement <newline> calcium-dependent cell-matrix adhesion ; GO:0016340 | inferred from sequence or structural similarity <newline> cell-matrix adhesion ; GO:0007160 | traceable author statement <newline> heterophilic cell-cell adhesion ; GO:0007157 | traceable author statement <newline> apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | non-traceable author statement <newline> cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement <newline> tracheal outgrowth, open tracheal system ; GO:0007426 | traceable author statement <newline> maintenance of epithelial integrity, open tracheal system ; GO:0035160 | inferred from mutant phenotype <newline> hemocyte migration ; GO:0035099 | inferred from genetic interaction with Gef26 inferred from genetic interaction with R <newline> substrate-bound cell migration, cell extension ; GO:0006930 | inferred from genetic interaction with Gef26 <newline> determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> integrin-mediated signaling pathway ; GO:0007229 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812 <newline> cell-matrix adhesion ; GO:0007160 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812","focal adhesion ; GO:0005925 | inferred from sequence or structural similarity <newline> integrin complex ; GO:0008305 | inferred from sequence or structural similarity <newline> integrin complex ; GO:0008305 | non-traceable author statement <newline> cell leading edge ; GO:0031252 | inferred from direct assay <newline> integrin complex ; GO:0008305 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812","cell adhesion molecule binding ; GO:0050839 | traceable author statement <newline> receptor activity ; GO:0004872 | traceable author statement <newline> receptor activity ; GO:0004872 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812 <newline> binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812"]
[null,"FBgn0086899","Tousled-like kinase","tlk","The gene Tousled-like kinase is referred to in FlyBase by the symbol Dmel\\tlk (CG34412, FBgn0086899). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3614054..3682010. It has the cytological map location 3F1-3E7. There is experimental evidence that it has the molecular function</span>: protein binding; protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; protein amino acid autophosphorylation; mitotic cell cycle, embryonic; chromatin organization; chromosome segregation; protein amino acid phosphorylation; cell adhesion; histone phosphorylation; antimicrobial humoral response; regulation of cell cycle. 83 alleles are reported. The phenotypes of these alleles are annotated with: larval salivary gland; eye; macrochaeta; head. It has 8 annotated transcripts and 8 annotated polypeptides.","protein amino acid phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with EMBL:AF045253 <newline> cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> chromatin organization ; GO:0006325 | inferred from genetic interaction with asf1 <newline> histone phosphorylation ; GO:0016572 | inferred from mutant phenotype <newline> mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype <newline> protein amino acid autophosphorylation ; GO:0046777 | inferred from direct assay <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype <newline> chromosome segregation ; GO:0007059 | inferred from genetic interaction with mars","nucleus ; GO:0005634 | inferred from direct assay","protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with EMBL:AF045253 <newline> protein kinase activity ; GO:0004672 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with asf1 <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC_gene:TLK1; HGNC:11841; OMIM:608438 AND inferred from sequence or structural similarity with HGNC_gene:TLK2; HGNC:11842; OMIM:608439 AND inferred from sequence or structural similarity with TAIR:gene:1944622 <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with EMBL:AF045252; protein_id:AAC02225.1 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0259211","grainy head","grh","The gene grainy head is referred to in FlyBase by the symbol Dmel\\grh (CG42311, FBgn0259211). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13690294..13729118. It has the cytological map location 54E10-54F1. There is experimental evidence that it has the molecular function</span>: specific RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; nervous system development; tracheal outgrowth, open tracheal system; regulation of cell proliferation; open tracheal system development; regulation of tube length, open tracheal system; plasma membrane organization; chitin-based embryonic cuticle biosynthetic process. 70 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; embryonic/larval tracheal system; somatic stem cell; cephalopharyngeal skeleton; portion of tissue; cuticle; adult segment; larval abdominal segment; adult mesothoracic segment; developing anatomical structure. It has 7 annotated transcripts and 7 annotated polypeptides.","plasma membrane organization ; GO:0007009 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype <newline> tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from expression pattern <newline> ganglion mother cell fate determination ; GO:0007402 | traceable author statement <newline> ventral cord development ; GO:0007419 | non-traceable author statement <newline> nervous system development ; GO:0007399 | inferred from mutant phenotype <newline> regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype <newline> cellular membrane organization ; GO:0016044 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> primary branching, open tracheal system ; GO:0007428 | traceable author statement <newline> regulation of tube architecture, open tracheal system ; GO:0035152 | traceable author statement","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","DNA binding ; GO:0003677 | inferred from direct assay <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from direct assay <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement"]
[null,"FBgn0030749","Annexin B11","Anxb11","The gene Annexin B11 is referred to in FlyBase by the symbol Dmel\\Anxb11 (CG9968, FBgn0030749). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; cell adhesion. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Annexin; Annexin repeat; Annexin repeat, conserved site. Gene sequence location is X:16311269..16316249.","cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype","cellular_component ; GO:0005575 | no biological data available","calcium-dependent phospholipid binding ; GO:0005544 | non-traceable author statement <newline> actin binding ; GO:0003779 | inferred from sequence or structural similarity <newline> calcium-dependent phospholipid binding ; GO:0005544 | inferred from electronic annotation with InterPro:IPR001464, InterPro:IPR018252, InterPro:IPR018502 <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001464, InterPro:IPR018252, InterPro:IPR018502"]
[null,"FBgn0066365","dusky-like","dyl","The gene dusky-like is referred to in FlyBase by the symbol Dmel\\dyl (CG15013, FBgn0066365). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of chitin-based cuticle. There is experimental evidence that it is involved in the biological process</span>: regulation of embryonic cell shape; cell-matrix adhesion; actin filament organization. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Endoglin/CD105 antigen. Gene sequence location is 3L:4293995..4307711.","regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype <newline> cell-matrix adhesion ; GO:0007160 | inferred from mutant phenotype <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype","filamentous actin ; GO:0031941 | inferred from direct assay <newline> apical cortex ; GO:0045179 | inferred from direct assay","structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with dy"]
[null,"FBgn0035411","Girdin","Girdin","The gene Girdin is referred to in FlyBase by the symbol Dmel\\Girdin (CG12734, FBgn0035411). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: microtubule binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of cell size; actin filament organization. 8 alleles are reported. The phenotype of these alleles is annotated with: wing vein. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: HOOK. Gene sequence location is 3L:3178934..3185287.","microtubule cytoskeleton organization ; GO:0000226 | inferred from electronic annotation with InterPro:IPR008636 <newline> positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR008636","microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR008636"]
[]
["Cell Adhesion"]
[null,"FBgn0000117","armadillo","arm","The gene armadillo is referred to in FlyBase by the symbol Dmel\\arm (CG11579, FBgn0000117). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1785434..1794673. It has the cytological map location 2B14. There is experimental evidence that it has the molecular function</span>: transcription activator activity; protein binding; transcription coactivator activity. There is experimental evidence for 22 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; cell adhesion; positive regulation of cellular biosynthetic process; regulation of developmental process; sensory organ development; positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; stem cell differentiation; reproductive process in a multicellular organism; delamination; cell junction organization. 177 alleles are reported. The phenotypes of these alleles are annotated with 100 unique terms, many of which group under: organ system; adult segment; abdominal ventral denticle belt; embryonic nervous system; female germline cyst; adult mesothoracic segment; embryonic/larval tracheal system; embryonic neuron; external compound sense organ; peripheral nervous system. It has 5 annotated transcripts and 5 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from sequence or structural similarity with MGD:Catnb; MGI:MGI:88276 <newline> cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | non-traceable author statement <newline> neuroblast fate determination ; GO:0007400 | non-traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> oocyte localization during germarium-derived egg chamber formation ; GO:0030720 | traceable author statement <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> heart development ; GO:0007507 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> positive regulation of JNK cascade ; GO:0046330 | traceable author statement <newline> protein localization ; GO:0008104 | traceable author statement <newline> germ-line stem cell division ; GO:0042078 | non-traceable author statement <newline> zonula adherens assembly ; GO:0045186 | traceable author statement <newline> establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement <newline> somatic stem cell maintenance ; GO:0035019 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype <newline> zonula adherens assembly ; GO:0045186 | inferred from mutant phenotype <newline> cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype <newline> cell morphogenesis ; GO:0000902 | inferred from mutant phenotype <newline> ventral furrow formation ; GO:0007370 | inferred from mutant phenotype <newline> neuroblast development ; GO:0014019 | inferred from mutant phenotype <newline> photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> compound eye retinal cell programmed cell death ; GO:0046667 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from direct assay <newline> imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype <newline> delamination ; GO:0060232 | inferred from mutant phenotype <newline> wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | inferred from mutant phenotype <newline> positive regulation of transcription ; GO:0045941 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | inferred from mutant phenotype","zonula adherens ; GO:0005915 | inferred from direct assay <newline> catenin complex ; GO:0016342 | inferred from sequence or structural similarity <newline> adherens junction ; GO:0005912 | non-traceable author statement <newline> catenin complex ; GO:0016342 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | non-traceable author statement <newline> membrane ; GO:0016020 | non-traceable author statement <newline> apicolateral plasma membrane ; GO:0016327 | traceable author statement <newline> adherens junction ; GO:0005912 | inferred from direct assay <newline> adherens junction ; GO:0005912 | traceable author statement <newline> cytoplasm ; GO:0005737 | traceable author statement <newline> spot adherens junction ; GO:0005914 | non-traceable author statement <newline> zonula adherens ; GO:0005915 | non-traceable author statement <newline> zonula adherens ; GO:0005915 | traceable author statement <newline> apical plasma membrane ; GO:0016324 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from physical interaction with pygo <newline> cytoplasm ; GO:0005737 | inferred from direct assay","cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity <newline> protein binding ; GO:0005515 | inferred from physical interaction with Apc2 AND inferred from physical interaction with Mer <newline> alpha-catenin binding ; GO:0045294 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P22265 <newline> transcription activator activity ; GO:0016563 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with Apc2 <newline> transcription coactivator activity ; GO:0003713 | inferred from direct assay"]
[null,"FBgn0000497","dachsous","ds","The gene dachsous is referred to in FlyBase by the symbol Dmel\\ds (CG17941, FBgn0000497). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:640021..714968. It has the cytological map location 21E2. There is experimental evidence that it has the molecular function</span>: cell adhesion molecule binding. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; establishment of planar polarity; sensory organ development; organ development; cell morphogenesis; epithelial cell differentiation; cell proliferation; biopolymer modification; cell adhesion. 60 alleles are reported. The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; thoracic segment; peripheral nervous system; external compound sense organ; nervous system; appendage segment; wing hair; dorsal thoracic disc; adult cuticle. It has one annotated transcript and one annotated polypeptide.","establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from mutant phenotype <newline> cell morphogenesis involved in differentiation ; GO:0000904 | inferred from mutant phenotype <newline> peptide cross-linking ; GO:0018149 | inferred from physical interaction with ft <newline> calcium-dependent cell-cell adhesion ; GO:0016339 | inferred from sequence or structural similarity <newline> establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype <newline> equator specification ; GO:0045317 | inferred from mutant phenotype <newline> establishment of epithelial cell apical/basal polarity ; GO:0045198 | inferred from mutant phenotype <newline> wing disc pattern formation ; GO:0035222 | inferred from mutant phenotype <newline> establishment of cell polarity ; GO:0030010 | inferred from mutant phenotype <newline> eye morphogenesis ; GO:0048592 | inferred from mutant phenotype <newline> imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> homophilic cell adhesion ; GO:0007156 | inferred from sequence or structural similarity <newline> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | traceable author statement <newline> ommatidial rotation ; GO:0016318 | traceable author statement <newline> establishment of tissue polarity ; GO:0007164 | non-traceable author statement <newline> establishment of planar polarity ; GO:0001736 | traceable author statement <newline> establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement <newline> calcium-dependent cell-cell adhesion ; GO:0016339 | inferred from sequence or structural similarity with UniProtKB:P33450 <newline> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype <newline> cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype <newline> homophilic cell adhesion ; GO:0007156 | inferred from electronic annotation with InterPro:IPR000233, InterPro:IPR002126","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> integral to plasma membrane ; GO:0005887 | inferred from sequence or structural similarity <newline> integral to membrane ; GO:0016021 | traceable author statement <newline> integral to plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with UniProtKB:P33450","cell adhesion molecule binding ; GO:0050839 | inferred from direct assay <newline> cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity <newline> receptor activity ; GO:0004872 | inferred from sequence or structural similarity <newline> signal transducer activity ; GO:0004871 | non-traceable author statement <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR000233, InterPro:IPR002126, InterPro:IPR015919"]
[null,"FBgn0000547","echinoid","ed","The gene echinoid is referred to in FlyBase by the symbol Dmel\\ed (CG12676, FBgn0000547). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:4031379..4115059. It has the cytological map location 24D4-24D6. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; organ development; cell adhesion; regulation of developmental process; regulation of biological process; cell-cell adhesion; homophilic cell adhesion; regulation of neurogenesis; actin filament-based process; behavioral interaction between organisms; regulation of epidermal growth factor receptor signaling pathway. 60 alleles are reported. The phenotypes of these alleles are annotated with 29 unique terms, many of which group under: peripheral nervous system; external compound sense organ; nervous system; adult segment; adult mesothoracic segment; embryonic nervous system; organ system; histaminergic neuron; embryonic segment; primordium. It has one annotated transcript and one annotated polypeptide.","epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype <newline> cell adhesion ; GO:0007155 | inferred from sequence or structural similarity <newline> negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with Egfr AND inferred from genetic interaction with Gap1 AND inferred from genetic interaction with Ras85D AND inferred from genetic interaction with argos AND inferred from genetic interaction with rho AND inferred from genetic interaction with rl AND inferred from genetic interaction with sty AND inferred from mutant phenotype <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype AND inferred from physical interaction with Nrg <newline> negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> homophilic cell adhesion ; GO:0007156 | inferred from direct assay AND inferred from mutant phenotype <newline> negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype <newline> contractile actin filament bundle assembly ; GO:0030038 | inferred from mutant phenotype <newline> muscle organ morphogenesis ; GO:0048644 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype <newline> mushroom body development ; GO:0016319 | inferred from mutant phenotype","integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> cell-cell adherens junction ; GO:0005913 | inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with Grip"]
[null,"FBgn0002543","leak","lea","The gene leak is referred to in FlyBase by the symbol Dmel\\lea (CG5481, FBgn0002543). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:1380086..1420449. It has the cytological map location 22A1. It is reported to have molecular function</span>: axon guidance receptor activity; receptor activity. There is experimental evidence that it is involved in the biological process</span>: salivary gland boundary specification; axon guidance; cardioblast cell fate specification; positive regulation of cell-cell adhesion; mushroom body development; embryonic heart tube development; neuron migration; ventral cord development; central complex development. 35 alleles are reported. The phenotypes of these alleles are annotated with 41 unique terms, many of which group under: organ system; nervous system; multi-cell-component structure; embryonic nervous system; adult segment; peripheral nervous system; embryonic neuron; abdominal transverse muscle; cephalopharyngeal skeleton; commissure. It has one annotated transcript and one annotated polypeptide.","axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> ventral cord development ; GO:0007419 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | traceable author statement <newline> tracheal outgrowth, open tracheal system ; GO:0007426 | traceable author statement <newline> neuron migration ; GO:0001764 | inferred from mutant phenotype <newline> salivary gland boundary specification ; GO:0007432 | inferred from mutant phenotype <newline> embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from genetic interaction with robo AND inferred from mutant phenotype <newline> positive regulation of cell-cell adhesion ; GO:0022409 | inferred from mutant phenotype <newline> cardioblast cell fate specification ; GO:0042685 | inferred from mutant phenotype <newline> mushroom body development ; GO:0016319 | inferred from mutant phenotype <newline> central complex development ; GO:0048036 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | non-traceable author statement","axon guidance receptor activity ; GO:0008046 | non-traceable author statement <newline> receptor activity ; GO:0004872 | traceable author statement"]
[null,"FBgn0004101","blistered","bs","The gene blistered is referred to in FlyBase by the symbol Dmel\\bs (CG3411, FBgn0004101). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20231236..20263998. It has the cytological map location 60C6-60C7. It is reported to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: apposition of dorsal and ventral imaginal disc-derived wing surfaces; terminal branching, open tracheal system; imaginal disc-derived wing morphogenesis; sleep; open tracheal system development. 61 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; thoracic segment; tracheal system; embryonic/larval tracheal system; appendage segment; cuticle; wing cell; embryonic tracheal system; organ system subdivision; cephalopharyngeal skeleton; peripheral nervous system. It has 2 annotated transcripts and 2 annotated polypeptides.","open tracheal system development ; GO:0007424 | inferred from expression pattern <newline> terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype <newline> terminal branching, open tracheal system ; GO:0007430 | traceable author statement <newline> apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype <newline> cell fate commitment ; GO:0045165 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> terminal cell fate specification, open tracheal system ; GO:0035154 | traceable author statement <newline> open tracheal system development ; GO:0007424 | non-traceable author statement <newline> terminal branching, open tracheal system ; GO:0007430 | non-traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> sleep ; GO:0030431 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR002100","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR002100 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR002100"]
[null,"FBgn0004449","Tenascin major","Ten-m","The gene Tenascin major is referred to in FlyBase by the symbol Dmel\\Ten-m (CG5723, FBgn0004449). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:22286132..22400987. It has the cytological map location 79D4-79E3. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; R7 cell development; bristle development; compound eye photoreceptor development; periodic partitioning by pair rule gene; compound eye corneal lens development; cell adhesion; compound eye morphogenesis. 47 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; abdominal ventral denticle belt; cuticle; larval abdominal segment; external compound sense organ; nervous system; peripheral nervous system; thoracic segment; metathoracic ventral denticle belt; embryonic head; embryonic nervous system; abdominal 5 ventral denticle belt. It has 2 annotated transcripts and 2 annotated polypeptides.","cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> cell adhesion ; GO:0007155 | inferred from sequence or structural similarity with EMBL:AB025410 <newline> periodic partitioning by pair rule gene ; GO:0007366 | inferred from mutant phenotype <newline> compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype <newline> R7 cell development ; GO:0045467 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> bristle development ; GO:0022416 | inferred from mutant phenotype <newline> compound eye corneal lens development ; GO:0048058 | inferred from mutant phenotype","proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity <newline> integral to plasma membrane ; GO:0005887 | inferred from direct assay <newline> proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with EMBL:AB025410","-"]
[null,"FBgn0004657","myospheroid","mys","The gene myospheroid is referred to in FlyBase by the symbol Dmel\\mys (CG1560, FBgn0004657). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7955680..7964270. It has the cytological map location 7D5. It is reported to have molecular function</span>: cell adhesion molecule binding; receptor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; central nervous system development; germ-line stem cell maintenance; determination of adult lifespan; axon guidance; hemocyte migration; cell adhesion; muscle organ development; maintenance of epithelial integrity, open tracheal system; substrate-bound cell migration, cell extension. 141 alleles are reported. The phenotypes of these alleles are annotated with 55 unique terms, many of which group under: organ system; hypodermal muscle of larval abdomen; adult segment; primordium; nervous system; larval abdominal segment 5; adult mesothoracic segment; larval abdominal segment; extended germ band embryo; abdominal 7 longitudinal muscle; external compound sense organ. It has one annotated transcript and one annotated polypeptide.","central nervous system development ; GO:0007417 | inferred from mutant phenotype <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> cell migration ; GO:0016477 | traceable author statement <newline> midgut development ; GO:0007494 | traceable author statement <newline> muscle attachment ; GO:0016203 | traceable author statement <newline> calcium-dependent cell-cell adhesion ; GO:0016339 | traceable author statement <newline> calcium-dependent cell-matrix adhesion ; GO:0016340 | inferred from sequence or structural similarity <newline> cell-matrix adhesion ; GO:0007160 | traceable author statement <newline> heterophilic cell-cell adhesion ; GO:0007157 | traceable author statement <newline> apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | non-traceable author statement <newline> cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement <newline> tracheal outgrowth, open tracheal system ; GO:0007426 | traceable author statement <newline> maintenance of epithelial integrity, open tracheal system ; GO:0035160 | inferred from mutant phenotype <newline> hemocyte migration ; GO:0035099 | inferred from genetic interaction with Gef26 inferred from genetic interaction with R <newline> substrate-bound cell migration, cell extension ; GO:0006930 | inferred from genetic interaction with Gef26 <newline> determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> integrin-mediated signaling pathway ; GO:0007229 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812 <newline> cell-matrix adhesion ; GO:0007160 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812","focal adhesion ; GO:0005925 | inferred from sequence or structural similarity <newline> integrin complex ; GO:0008305 | inferred from sequence or structural similarity <newline> integrin complex ; GO:0008305 | non-traceable author statement <newline> cell leading edge ; GO:0031252 | inferred from direct assay <newline> integrin complex ; GO:0008305 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812","cell adhesion molecule binding ; GO:0050839 | traceable author statement <newline> receptor activity ; GO:0004872 | traceable author statement <newline> receptor activity ; GO:0004872 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812 <newline> binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812"]
[null,"FBgn0005775","Connectin","Con","The gene Connectin is referred to in FlyBase by the symbol Dmel\\Con (CG7503, FBgn0005775). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4938048..4976172. It has the cytological map location 64C2-64C4. Its molecular function is unknown. It is reported to be involved in the biological process</span>: homophilic cell adhesion; axonal fasciculation; cell adhesion; synaptic target attraction. 14 alleles are reported. The phenotypes of these alleles are annotated with 37 unique terms, many of which group under: hypodermal muscle of larval abdomen; abdominal oblique muscle; organ system; larval abdominal segment 5; abdominal ventral oblique muscle 4; hypodermal muscle of larval abdominal 2; abdominal 7 longitudinal muscle; embryonic neuron; abdominal segment 7; abdominal 6 longitudinal muscle. It has one annotated transcript and one annotated polypeptide.","cell adhesion ; GO:0007155 | non-traceable author statement <newline> axonal fasciculation ; GO:0007413 | traceable author statement <newline> homophilic cell adhesion ; GO:0007156 | traceable author statement <newline> synaptic target attraction ; GO:0016200 | traceable author statement <newline> homophilic cell adhesion ; GO:0007156 | non-traceable author statement","plasma membrane ; GO:0005886 | traceable author statement","-"]
[null,"FBgn0015229","gliolectin","glec","The gene gliolectin is referred to in FlyBase by the symbol Dmel\\glec (CG6575, FBgn0015229). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17676627..17681984. It has the cytological map location 93F14. There is experimental evidence that it has the molecular function</span>: carbohydrate binding. There is experimental evidence that it is involved in the biological process</span>: heterophilic cell adhesion; nervous system development. 19 alleles are reported. The phenotypes of these alleles are annotated with: ventral nerve cord commissure; trichogen cell; macrochaeta; pCC neuron; scutellar bristle. It has one annotated transcript and one annotated polypeptide.","heterophilic cell-cell adhesion ; GO:0007157 | inferred from mutant phenotype <newline> cell adhesion ; GO:0007155 | non-traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> nervous system development ; GO:0007399 | inferred from expression pattern AND inferred from mutant phenotype","integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> membrane fraction ; GO:0005624 | inferred from direct assay","carbohydrate binding ; GO:0030246 | inferred from direct assay <newline> carbohydrate binding ; GO:0030246 | non-traceable author statement"]
[null,"FBgn0027108","innexin 2","inx2","The gene innexin 2 is referred to in FlyBase by the symbol Dmel\\inx2 (CG4590, FBgn0027108). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6892696..6898182. It has the cytological map location 6E4. It is reported to have molecular function</span>: gap junction channel activity. There is experimental evidence that it is involved in the biological process</span>: morphogenesis of embryonic epithelium; olfactory behavior; foregut morphogenesis. 41 alleles are reported. The phenotypes of these alleles are annotated with: embryonic hindgut; embryonic salivary gland; embryonic head; embryonic segment; proventriculus primordium; embryonic Malpighian tubule; embryonic/larval proventriculus; embryonic epidermis; embryonic tracheal system; embryonic foregut. It has 3 annotated transcripts and 3 annotated polypeptides.","foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype <newline> morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype <newline> olfactory behavior ; GO:0042048 | inferred from mutant phenotype","gap junction ; GO:0005921 | non-traceable author statement <newline> gap junction ; GO:0005921 | inferred from sequence or structural similarity with EMBL:AF115854; protein_id:AAD29306.1 <newline> integral to membrane ; GO:0016021 | non-traceable author statement <newline> gap junction ; GO:0005921 | inferred from direct assay","gap junction channel activity ; GO:0005243 | non-traceable author statement"]
[null,"FBgn0031850","Thrombospondin","Tsp","The gene Thrombospondin is referred to in FlyBase by the symbol Dmel\\Tsp (CG11326, FBgn0031850). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:6686786..6709085. It has the cytological map location 26F7-27A1. There is experimental evidence that it has the molecular function</span>: heparin binding. There is experimental evidence that it is involved in the biological process</span>: muscle organ development; cell adhesion mediated by integrin; muscle attachment. 17 alleles are reported. The phenotypes of these alleles are annotated with: tendon cell; dorsal oblique muscle; lateral longitudinal muscle; dorsal acute muscle; embryonic/larval muscle system; ventral longitudinal muscle. It has 6 annotated transcripts and 6 annotated polypeptides.","cell adhesion mediated by integrin ; GO:0033627 | inferred from mutant phenotype <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> muscle attachment ; GO:0016203 | inferred from mutant phenotype","muscle tendon junction ; GO:0005927 | inferred from direct assay <newline> extracellular matrix ; GO:0031012 | inferred from direct assay <newline> protein complex ; GO:0043234 | inferred from direct assay","heparin binding ; GO:0008201 | inferred from direct assay <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR003367, InterPro:IPR008859, InterPro:IPR018097"]
[null,"FBgn0086899","Tousled-like kinase","tlk","The gene Tousled-like kinase is referred to in FlyBase by the symbol Dmel\\tlk (CG34412, FBgn0086899). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3614054..3682010. It has the cytological map location 3F1-3E7. There is experimental evidence that it has the molecular function</span>: protein binding; protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; protein amino acid autophosphorylation; mitotic cell cycle, embryonic; chromatin organization; chromosome segregation; protein amino acid phosphorylation; cell adhesion; histone phosphorylation; antimicrobial humoral response; regulation of cell cycle. 83 alleles are reported. The phenotypes of these alleles are annotated with: larval salivary gland; eye; macrochaeta; head. It has 8 annotated transcripts and 8 annotated polypeptides.","protein amino acid phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with EMBL:AF045253 <newline> cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> chromatin organization ; GO:0006325 | inferred from genetic interaction with asf1 <newline> histone phosphorylation ; GO:0016572 | inferred from mutant phenotype <newline> mitotic cell cycle, embryonic ; GO:0045448 | inferred from mutant phenotype <newline> protein amino acid autophosphorylation ; GO:0046777 | inferred from direct assay <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype <newline> chromosome segregation ; GO:0007059 | inferred from genetic interaction with mars","nucleus ; GO:0005634 | inferred from direct assay","protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with EMBL:AF045253 <newline> protein kinase activity ; GO:0004672 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with asf1 <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with HGNC_gene:TLK1; HGNC:11841; OMIM:608438 AND inferred from sequence or structural similarity with HGNC_gene:TLK2; HGNC:11842; OMIM:608439 AND inferred from sequence or structural similarity with TAIR:gene:1944622 <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with EMBL:AF045252; protein_id:AAC02225.1 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0030749","Annexin B11","Anxb11","The gene Annexin B11 is referred to in FlyBase by the symbol Dmel\\Anxb11 (CG9968, FBgn0030749). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; cell adhesion. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Annexin; Annexin repeat; Annexin repeat, conserved site. Gene sequence location is X:16311269..16316249.","cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype","cellular_component ; GO:0005575 | no biological data available","calcium-dependent phospholipid binding ; GO:0005544 | non-traceable author statement <newline> actin binding ; GO:0003779 | inferred from sequence or structural similarity <newline> calcium-dependent phospholipid binding ; GO:0005544 | inferred from electronic annotation with InterPro:IPR001464, InterPro:IPR018252, InterPro:IPR018502 <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001464, InterPro:IPR018252, InterPro:IPR018502"]
[null,"FBgn0066365","dusky-like","dyl","The gene dusky-like is referred to in FlyBase by the symbol Dmel\\dyl (CG15013, FBgn0066365). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of chitin-based cuticle. There is experimental evidence that it is involved in the biological process</span>: regulation of embryonic cell shape; cell-matrix adhesion; actin filament organization. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Endoglin/CD105 antigen. Gene sequence location is 3L:4293995..4307711.","regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype <newline> cell-matrix adhesion ; GO:0007160 | inferred from mutant phenotype <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype","filamentous actin ; GO:0031941 | inferred from direct assay <newline> apical cortex ; GO:0045179 | inferred from direct assay","structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with dy"]
[null,"FBgn0262614","polychaetoid","pyd","The gene polychaetoid is referred to in FlyBase by the symbol Dmel\\pyd (CG43140, FBgn0262614). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: guanylate kinase activity. There is experimental evidence that it is involved in the biological process</span>: bristle development; wing disc development; cell-cell adhesion; fusion cell fate specification; branch fusion, open tracheal system. 66 alleles are reported. The phenotypes of these alleles are annotated with 27 unique terms, many of which group under: peripheral nervous system; organ system; adult segment; external compound sense organ; late extended germ band embryo; non-connected developing functional system; acellular anatomical structure; tracheal branch primordium; integumentary plate; appendage segment. It has 12 annotated transcripts and 12 annotated polypeptides. Protein features are: Guanylate kinase; Guanylate kinase/L-type calcium channel; PDZ/DHR/GLGF; Src homology-3 domain; Variant SH3; ZU5. Gene sequence location is 3R:4653200..4757599.","bristle development ; GO:0022416 | inferred from mutant phenotype <newline> wing disc development ; GO:0035220 | inferred from mutant phenotype <newline> JNK cascade ; GO:0007254 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> dorsal closure ; GO:0007391 | non-traceable author statement <newline> regulation of JNK cascade ; GO:0046328 | non-traceable author statement <newline> establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement <newline> branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype <newline> fusion cell fate specification ; GO:0035156 | inferred from mutant phenotype <newline> cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype","adherens junction ; GO:0005912 | inferred from direct assay <newline> adherens junction ; GO:0005912 | traceable author statement <newline> adherens junction ; GO:0005912 | non-traceable author statement <newline> cell-cell adherens junction ; GO:0005913 | inferred from direct assay","guanylate kinase activity ; GO:0004385 | inferred from sequence or structural similarity with HGNC_gene:TJP1; HGNC:11827; OMIM:601009 AND inferred from sequence or structural similarity with SGD_LOCUS:GUK1; SGD:S0002862 <newline> guanylate kinase activity ; GO:0004385 | non-traceable author statement"]
[null,"FBgn0001257","Ecdysone-inducible gene L2","ImpL2","The gene Ecdysone-inducible gene L2 is referred to in FlyBase by the symbol Dmel\\ImpL2 (CG15009, FBgn0001257). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. It is reported to be involved in the biological process</span>: cell adhesion. 15 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Immunoglobulin I-set; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold. Gene sequence location is 3L:4224699..4236147.","cell adhesion ; GO:0007155 | traceable author statement","extracellular region ; GO:0005576 | non-traceable author statement","-"]
[null,"FBgn0262114","Ran-binding protein M","RanBPM","The gene Ran-binding protein M is referred to in FlyBase by the symbol Dmel\\RanBPM (CG42236, FBgn0262114). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: Ran GTPase binding. There is experimental evidence that it is involved in the biological process</span>: larval feeding behavior; ovarian follicle cell-cell adhesion; germ-line stem-cell niche homeostasis; cytoskeleton organization; dorsal appendage formation. 14 alleles are reported. The phenotypes of these alleles are annotated with: terminal filament; ovary; germline stem cell; germarium cap cell; egg chamber. It has 4 annotated transcripts and 4 annotated polypeptides. Gene sequence location is 2R:6317217..6324086.","germ-line stem-cell niche homeostasis ; GO:0060250 | inferred from mutant phenotype <newline> cytoskeleton organization ; GO:0007010 | inferred from direct assay <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> ovarian follicle cell-cell adhesion ; GO:0007299 | inferred from mutant phenotype <newline> larval feeding behavior ; GO:0030536 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay","Ran GTPase binding ; GO:0008536 | inferred from sequence or structural similarity with HGNC_gene:RANBP9; HGNC:13727"]
[null,"FBgn0261284","boudin","bou","The gene boudin is referred to in FlyBase by the symbol Dmel\\bou (CG14430, FBgn0261284). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: regulation of tube architecture, open tracheal system; septate junction assembly. 16 alleles are reported. The phenotypes of these alleles are annotated with: septate junction; embryonic/larval tracheal system; embryonic tracheal system; chordotonal organ; imaginal disc; dorsal trunk primordium. It has one annotated transcript and one annotated polypeptide. Gene sequence location is X:6880523..6881236.","regulation of tube architecture, open tracheal system ; GO:0035152 | inferred from mutant phenotype <newline> septate junction assembly ; GO:0019991 | inferred from mutant phenotype","anchored to plasma membrane ; GO:0046658 | inferred from direct assay <newline> extracellular region ; GO:0005576 | inferred from direct assay","-"]
[]
["Cytoskeletal Proteins "]
[null,"FBgn0000117","armadillo","arm","The gene armadillo is referred to in FlyBase by the symbol Dmel\\arm (CG11579, FBgn0000117). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1785434..1794673. It has the cytological map location 2B14. There is experimental evidence that it has the molecular function</span>: transcription activator activity; protein binding; transcription coactivator activity. There is experimental evidence for 22 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; cell adhesion; positive regulation of cellular biosynthetic process; regulation of developmental process; sensory organ development; positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; stem cell differentiation; reproductive process in a multicellular organism; delamination; cell junction organization. 177 alleles are reported. The phenotypes of these alleles are annotated with 100 unique terms, many of which group under: organ system; adult segment; abdominal ventral denticle belt; embryonic nervous system; female germline cyst; adult mesothoracic segment; embryonic/larval tracheal system; embryonic neuron; external compound sense organ; peripheral nervous system. It has 5 annotated transcripts and 5 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from sequence or structural similarity with MGD:Catnb; MGI:MGI:88276 <newline> cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | non-traceable author statement <newline> neuroblast fate determination ; GO:0007400 | non-traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> oocyte localization during germarium-derived egg chamber formation ; GO:0030720 | traceable author statement <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> heart development ; GO:0007507 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> positive regulation of JNK cascade ; GO:0046330 | traceable author statement <newline> protein localization ; GO:0008104 | traceable author statement <newline> germ-line stem cell division ; GO:0042078 | non-traceable author statement <newline> zonula adherens assembly ; GO:0045186 | traceable author statement <newline> establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement <newline> somatic stem cell maintenance ; GO:0035019 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype <newline> zonula adherens assembly ; GO:0045186 | inferred from mutant phenotype <newline> cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype <newline> cell morphogenesis ; GO:0000902 | inferred from mutant phenotype <newline> ventral furrow formation ; GO:0007370 | inferred from mutant phenotype <newline> neuroblast development ; GO:0014019 | inferred from mutant phenotype <newline> photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> compound eye retinal cell programmed cell death ; GO:0046667 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from direct assay <newline> imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype <newline> delamination ; GO:0060232 | inferred from mutant phenotype <newline> wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | inferred from mutant phenotype <newline> positive regulation of transcription ; GO:0045941 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | inferred from mutant phenotype","zonula adherens ; GO:0005915 | inferred from direct assay <newline> catenin complex ; GO:0016342 | inferred from sequence or structural similarity <newline> adherens junction ; GO:0005912 | non-traceable author statement <newline> catenin complex ; GO:0016342 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | non-traceable author statement <newline> membrane ; GO:0016020 | non-traceable author statement <newline> apicolateral plasma membrane ; GO:0016327 | traceable author statement <newline> adherens junction ; GO:0005912 | inferred from direct assay <newline> adherens junction ; GO:0005912 | traceable author statement <newline> cytoplasm ; GO:0005737 | traceable author statement <newline> spot adherens junction ; GO:0005914 | non-traceable author statement <newline> zonula adherens ; GO:0005915 | non-traceable author statement <newline> zonula adherens ; GO:0005915 | traceable author statement <newline> apical plasma membrane ; GO:0016324 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from physical interaction with pygo <newline> cytoplasm ; GO:0005737 | inferred from direct assay","cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity <newline> protein binding ; GO:0005515 | inferred from physical interaction with Apc2 AND inferred from physical interaction with Mer <newline> alpha-catenin binding ; GO:0045294 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P22265 <newline> transcription activator activity ; GO:0016563 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with Apc2 <newline> transcription coactivator activity ; GO:0003713 | inferred from direct assay"]
[null,"FBgn0000308","chickadee","chic","The gene chickadee is referred to in FlyBase by the symbol Dmel\\chic (CG9553, FBgn0000308). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:5972900..5981025. It has the cytological map location 26A5-26B2. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; central nervous system development; multicellular organism reproduction; organelle organization; organ development; post-embryonic morphogenesis; cell morphogenesis; gamete generation; cell division; actin filament-based process; ovarian nurse cell to oocyte transport; cellular localization. 65 alleles are reported. The phenotypes of these alleles are annotated with 32 unique terms, many of which group under: organ system; female germline cyst; peripheral nervous system; adult segment; nervous system; multi-cell-component structure; egg; spermatocyte; male germline cyst; embryonic nervous system; adult mesothoracic segment; portion of tissue. It has 4 annotated transcripts and 4 annotated polypeptides.","ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype <newline> spermatogenesis ; GO:0007283 | inferred from mutant phenotype <newline> brain development ; GO:0007420 | inferred from genetic interaction with cib <newline> larval central nervous system remodeling ; GO:0035193 | inferred from genetic interaction with cib <newline> cytokinesis, actomyosin contractile ring assembly ; GO:0000915 | traceable author statement <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype <newline> cell morphogenesis ; GO:0000902 | inferred from mutant phenotype <newline> cytokinesis ; GO:0000910 | inferred from mutant phenotype <newline> brain development ; GO:0007420 | inferred from mutant phenotype <newline> actin polymerization or depolymerization ; GO:0008154 | non-traceable author statement <newline> actin filament organization ; GO:0007015 | traceable author statement <newline> pole plasm oskar mRNA localization ; GO:0045451 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> actin filament polymerization ; GO:0030041 | traceable author statement <newline> karyosome formation ; GO:0030717 | inferred from mutant phenotype <newline> histoblast morphogenesis ; GO:0007488 | inferred from mutant phenotype <newline> maintenance of protein location in cell ; GO:0032507 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype","actin cytoskeleton ; GO:0015629 | inferred from electronic annotation with InterPro:IPR002097","actin binding ; GO:0003779 | inferred from sequence or structural similarity <newline> actin binding ; GO:0003779 | non-traceable author statement <newline> phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8T4F7 <newline> protein binding ; GO:0005515 | inferred from physical interaction with dia <newline> actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR002097, InterPro:IPR005455"]
[null,"FBgn0000723","Fps oncogene analog","Fps85D","The gene Fps oncogene analog is referred to in FlyBase by the symbol Dmel\\Fps85D (CG8874, FBgn0000723). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5193321..5220265. It has the cytological map location 85D13-85D15. Based on sequence similarity, it is predicted to have molecular function</span>: protein tyrosine kinase activity. There is experimental evidence that it is involved in the biological process</span>: dorsal closure, elongation of leading edge cells; dorsal closure; actin filament bundle formation; axon guidance; photoreceptor cell morphogenesis; dorsal closure, amnioserosa morphology change. 18 alleles are reported. The phenotypes of these alleles are annotated with: dorsal closure embryo; amnioserosa; ventral midline. It has 4 annotated transcripts and 4 annotated polypeptides.","protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> photoreceptor cell morphogenesis ; GO:0008594 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from genetic interaction with Src42A <newline> dorsal closure, elongation of leading edge cells ; GO:0007394 | inferred from mutant phenotype <newline> dorsal closure, amnioserosa morphology change ; GO:0046664 | inferred from mutant phenotype <newline> actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR017441","plasma membrane ; GO:0005886 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | non-traceable author statement <newline> membrane ; GO:0016020 | non-traceable author statement <newline> adherens junction ; GO:0005912 | inferred from direct assay","protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity <newline> protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement <newline> protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity with UniProtKB:P00541 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR017441 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000980, InterPro:IPR020685"]
[null,"FBgn0001104","G protein alphai subunit 65A","G-ialpha65A","The gene G protein ?i subunit 65A is referred to in FlyBase by the symbol Dmel\\G-i?65A (CG10060, FBgn0001104). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:6965844..6973153. It has the cytological map location 65D5. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: asymmetric protein localization involved in cell fate determination; asymmetric neuroblast division; establishment of spindle orientation; establishment of glial blood-brain barrier; cortical actin cytoskeleton organization; septate junction assembly; regulation of protein localization; asymmetric cell division; ventral cord development. 28 alleles are reported. The phenotypes of these alleles are annotated with: RP2 neuron; neuroblast; embryonic neuroblast; chaeta; medial triple row; RP2sib neuron; EL neuron. It has one annotated transcript and one annotated polypeptide.","G-protein coupled receptor protein signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with UniProtKB:P41776 <newline> establishment of mitotic spindle localization ; GO:0040001 | traceable author statement <newline> asymmetric protein localization involved in cell fate determination ; GO:0045167 | inferred from mutant phenotype <newline> asymmetric cell division ; GO:0008356 | inferred from mutant phenotype <newline> G-protein coupled receptor protein signaling pathway ; GO:0007186 | non-traceable author statement <newline> establishment of spindle orientation ; GO:0051294 | inferred from mutant phenotype <newline> asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype <newline> regulation of protein localization ; GO:0032880 | inferred from mutant phenotype <newline> septate junction assembly ; GO:0019991 | inferred from mutant phenotype <newline> establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype <newline> ventral cord development ; GO:0007419 | inferred from mutant phenotype <newline> cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR011025","heterotrimeric G-protein complex ; GO:0005834 | inferred from sequence or structural similarity with UniProtKB:P41776 <newline> cell cortex ; GO:0005938 | traceable author statement <newline> heterotrimeric G-protein complex ; GO:0005834 | non-traceable author statement <newline> apical cortex ; GO:0045179 | inferred from direct assay","GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with UniProtKB:P41776 <newline> protein binding ; GO:0005515 | non-traceable author statement <newline> GTPase activity ; GO:0003924 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with raps <newline> protein binding ; GO:0005515 | inferred from physical interaction with loco <newline> GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001408 <newline> signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR001019, InterPro:IPR001408, InterPro:IPR011025"]
[null,"FBgn0001404","egghead","egh","The gene egghead is referred to in FlyBase by the symbol Dmel\\egh (CG9659, FBgn0001404). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2482534..2492638. It has the cytological map location 3A6. There is experimental evidence that it has the molecular function</span>: beta-1,4-mannosyltransferase activity. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: reproductive process in a multicellular organism; anatomical structure development; multicellular organism reproduction; ovarian follicle cell development; cellular component movement; organ morphogenesis; gamete generation; transport; regulation of response to stimulus; cell fate commitment; establishment or maintenance of polarity of follicular epithelium. 60 alleles are reported. The phenotypes of these alleles are annotated with 28 unique terms, many of which group under: organ system; adult segment; nervous system; multi-cell-component structure; female germline cyst; adult; peripheral nervous system; larval head segment; adult brain; egg; lamina plexus; embryonic nervous system; external compound sense organ. It has 2 annotated transcripts and 2 annotated polypeptides.","border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype <newline> ovarian follicle cell-cell adhesion ; GO:0007299 | inferred from mutant phenotype <newline> maintenance of polarity of follicular epithelium ; GO:0042248 | inferred from mutant phenotype <newline> morphogenesis of follicular epithelium ; GO:0016333 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> cell fate commitment ; GO:0045165 | inferred from mutant phenotype <newline> germ cell development ; GO:0007281 | inferred from mutant phenotype <newline> oocyte localization during germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype <newline> oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype <newline> optic lobe placode formation ; GO:0001744 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype <newline> regulation of oviposition ; GO:0046662 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | traceable author statement <newline> dsRNA transport ; GO:0033227 | inferred from mutant phenotype","integral to plasma membrane ; GO:0005887 | non-traceable author statement","beta-1,4-mannosyltransferase activity ; GO:0019187 | inferred from direct assay"]
[null,"FBgn0003502","Btk family kinase at 29A","Btk29A","The gene Btk family kinase at 29A is referred to in FlyBase by the symbol Dmel\\Btk29A (CG8049, FBgn0003502). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:8259504..8301072. It has the cytological map location 29A1-29A3. There is experimental evidence that it has the molecular function</span>: protein tyrosine kinase activity. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; ovarian nurse cell to oocyte transport; organelle organization; regulation of cellular component organization; gland morphogenesis; learning; determination of adult lifespan; cell cycle; actin filament-based process; multicellular organism reproduction. 48 alleles are reported. The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; cephalopharyngeal skeleton; female germline cyst; cuticle; integumentary specialisation; region of integument; embryonic foregut; adult; taenidial fold; mouthpart; actin cytoskeleton; egg; spiracle. It has 6 annotated transcripts and 6 annotated polypeptides.","protein amino acid phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with UniProtKB:Q06187 <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype <newline> female germline ring canal formation ; GO:0007301 | inferred from expression pattern <newline> determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> imaginal disc-derived male genitalia development ; GO:0007485 | inferred from direct assay AND inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> cellularization ; GO:0007349 | inferred from mutant phenotype <newline> actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype <newline> karyosome formation ; GO:0030717 | inferred from mutant phenotype <newline> ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype <newline> ovarian fusome organization ; GO:0030723 | inferred from mutant phenotype <newline> DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype <newline> regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> courtship behavior ; GO:0007619 | non-traceable author statement <newline> JNK cascade ; GO:0007254 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> sensitization ; GO:0046960 | inferred from mutant phenotype <newline> intracellular signaling pathway ; GO:0023034 | inferred from electronic annotation with InterPro:IPR001562","cytoplasm ; GO:0005737 | inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> germline ring canal ; GO:0045172 | inferred from direct assay <newline> germline ring canal ; GO:0045172 | traceable author statement","protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity with UniProtKB:Q06187 <newline> protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay <newline> protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement <newline> protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity with UniProtKB:P42680 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR017441 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000980, InterPro:IPR020685"]
[null,"FBgn0005634","zipper","zip","The gene zipper is referred to in FlyBase by the symbol Dmel\\zip (CG15792, FBgn0005634). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20878471..20899488. It has the cytological map location 60E12. There is experimental evidence that it has the molecular function</span>: myosin light chain binding. There is experimental evidence for 16 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; protein complex biogenesis; actin filament-based process; muscle cell differentiation; organ development; cell division; gland morphogenesis; epithelial cell differentiation; embryonic development via the syncytial blastoderm; establishment of protein localization; system process. 34 alleles are reported. The phenotypes of these alleles are annotated with 36 unique terms, many of which group under: organ system; cuticle; nervous system; peripheral nervous system; cytoplasmic part; external compound sense organ; adult segment; extended germ band embryo; acute muscle; cell projection; primordium. It has 8 annotated transcripts and 8 annotated polypeptides.","dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> muscle attachment ; GO:0016203 | NOT inferred from genetic interaction with l(2)gl <newline> muscle contraction ; GO:0006936 | inferred from mutant phenotype <newline> myofibril assembly ; GO:0030239 | inferred from mutant phenotype <newline> sarcomere organization ; GO:0045214 | inferred from mutant phenotype <newline> dorsal closure, leading edge cell differentiation ; GO:0046663 | inferred from mutant phenotype <newline> dorsal closure, spreading of leading edge cells ; GO:0007395 | inferred from mutant phenotype <newline> establishment of planar polarity ; GO:0001736 | non-traceable author statement <newline> cytokinesis ; GO:0000910 | inferred from mutant phenotype <newline> dorsal closure, amnioserosa morphology change ; GO:0046664 | inferred from mutant phenotype <newline> Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> ovarian follicle cell migration ; GO:0007297 | traceable author statement <newline> ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | non-traceable author statement <newline> establishment of neuroblast polarity ; GO:0045200 | traceable author statement <newline> cytokinesis ; GO:0000910 | non-traceable author statement <newline> anatomical structure morphogenesis ; GO:0009653 | non-traceable author statement <newline> imaginal disc-derived wing hair organization ; GO:0035317 | inferred from genetic interaction with fz inferred from genetic interaction with dsh <newline> cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype <newline> myosin II filament assembly ; GO:0031036 | inferred from direct assay <newline> protein oligomerization ; GO:0051259 | inferred from direct assay <newline> establishment of protein localization ; GO:0045184 | inferred from mutant phenotype","unconventional myosin complex ; GO:0016461 | inferred from sequence or structural similarity <newline> myosin complex ; GO:0016459 | inferred from sequence or structural similarity <newline> Z disc ; GO:0030018 | inferred from direct assay <newline> apical cortex ; GO:0045179 | traceable author statement <newline> cell cortex ; GO:0005938 | inferred from mutant phenotype <newline> cytoskeleton ; GO:0005856 | non-traceable author statement <newline> unconventional myosin complex ; GO:0016461 | non-traceable author statement <newline> myosin II complex ; GO:0016460 | inferred from direct assay <newline> cleavage furrow ; GO:0032154 | inferred from direct assay <newline> cell cortex ; GO:0005938 | inferred from direct assay","ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity <newline> motor activity ; GO:0003774 | inferred from sequence or structural similarity with SGD_LOCUS:MYO1; SGD:S0001065 <newline> myosin light chain binding ; GO:0032027 | inferred from physical interaction with sqh inferred from physical interaction with Mlc-c <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR004009"]
[null,"FBgn0010434","coracle","cora","The gene coracle is referred to in FlyBase by the symbol Dmel\\cora (CG11949, FBgn0010434). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15116570..15131256. It has the cytological map location 56C4. Based on sequence similarity, it is predicted to have molecular function</span>: cytoskeletal protein binding. There is experimental evidence that it is involved in the biological process</span>: embryonic morphogenesis; maintenance of imaginal disc-derived wing hair orientation; regulation of tube size, open tracheal system; establishment of glial blood-brain barrier. 42 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: peripheral nervous system; organ system; nervous system; external compound sense organ; plasma membrane part; integumentary plate; plasma membrane; embryonic head; embryonic dorsal trunk; wing hair; embryonic tracheal system. It has 4 annotated transcripts and 4 annotated polypeptides.","embryonic morphogenesis ; GO:0048598 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | traceable author statement <newline> salivary gland morphogenesis ; GO:0007435 | traceable author statement <newline> septate junction assembly ; GO:0019991 | traceable author statement <newline> protein targeting to membrane ; GO:0006612 | traceable author statement <newline> regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype <newline> maintenance of imaginal disc-derived wing hair orientation ; GO:0035321 | inferred from mutant phenotype <newline> cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity with EMBL:AB019257; protein_id:BAA76625.1 <newline> embryonic development ; GO:0009790 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | non-traceable author statement <newline> cell-cell junction organization ; GO:0045216 | traceable author statement <newline> establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement <newline> establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype","septate junction ; GO:0005918 | inferred from direct assay <newline> fusome ; GO:0045169 | NOT inferred from direct assay <newline> spectrosome ; GO:0045170 | NOT inferred from direct assay <newline> septate junction ; GO:0005918 | traceable author statement <newline> septate junction ; GO:0005918 | non-traceable author statement <newline> cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity with EMBL:AB019257; protein_id:BAA76625.1 <newline> apicolateral plasma membrane ; GO:0016327 | non-traceable author statement","cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity <newline> actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR008379 <newline> structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR008379"]
[null,"FBgn0011224","hephaestus","heph","The gene hephaestus is referred to in FlyBase by the symbol Dmel\\heph (CG31000, FBgn0011224). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27676704..27819000. It has the cytological map location 100D3-100E1. There is experimental evidence that it has the molecular function</span>: mRNA 3'-UTR binding; translation repressor activity, nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: spermatid development; imaginal disc-derived wing margin morphogenesis; oocyte microtubule cytoskeleton polarization; imaginal disc-derived wing vein morphogenesis; Notch signaling pathway; negative regulation of oskar mRNA translation. 106 alleles are reported. The phenotypes of these alleles are annotated with: macrochaeta; testis; wing; individualization stage spermatid; spermatozoon. It has 22 annotated transcripts and 22 annotated polypeptides.","spermatid development ; GO:0007286 | inferred from mutant phenotype <newline> nuclear mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with NCBI_NP:002810 <newline> Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> negative regulation of oskar mRNA translation ; GO:0007319 | inferred from mutant phenotype <newline> oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay <newline> ribonucleoprotein complex ; GO:0030529 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR006536","poly-pyrimidine tract binding ; GO:0008187 | non-traceable author statement <newline> mRNA binding ; GO:0003729 | inferred from sequence or structural similarity <newline> poly-pyrimidine tract binding ; GO:0008187 | inferred from sequence or structural similarity with NCBI_NP:002810 <newline> mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay <newline> translation repressor activity, nucleic acid binding ; GO:0000900 | inferred from mutant phenotype <newline> nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR012677"]
[null,"FBgn0011661","Moesin","Moe","The gene Moesin is referred to in FlyBase by the symbol Dmel\\Moe (CG10701, FBgn0011661). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8767636..8792343. It has the cytological map location 8B4-8B6. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: determination of left/right symmetry; olfactory behavior; oocyte anterior/posterior axis specification; actin cytoskeleton organization; establishment or maintenance of epithelial cell apical/basal polarity; establishment or maintenance of polarity of larval imaginal disc epithelium; rhabdomere membrane biogenesis; rhabdomere development; regulation of actin cytoskeleton organization; regulation of membrane potential in photoreceptor cell. 84 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; thoracic segment; imaginal precursor; embryonic hindgut; embryonic dorsal trunk; dorsal thoracic disc; external compound sense organ; neuron; embryonic foregut; peripheral nervous system. It has 10 annotated transcripts and 10 annotated polypeptides.","establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from mutant phenotype <newline> establishment or maintenance of polarity of larval imaginal disc epithelium ; GO:0016336 | inferred from mutant phenotype <newline> actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype <newline> anterior/posterior pattern formation ; GO:0009952 | traceable author statement <newline> cytoskeleton organization ; GO:0007010 | traceable author statement <newline> establishment or maintenance of apical/basal cell polarity ; GO:0035088 | traceable author statement <newline> eye photoreceptor cell development ; GO:0042462 | traceable author statement <newline> morphogenesis of an epithelium ; GO:0002009 | traceable author statement <newline> pole plasm assembly ; GO:0007315 | traceable author statement <newline> pole plasm protein localization ; GO:0007318 | traceable author statement <newline> protein localization ; GO:0008104 | traceable author statement <newline> rhabdomere development ; GO:0042052 | inferred from mutant phenotype <newline> rhabdomere membrane biogenesis ; GO:0045313 | inferred from mutant phenotype <newline> actin filament-based process ; GO:0030029 | non-traceable author statement <newline> olfactory behavior ; GO:0042048 | inferred from mutant phenotype <newline> oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype <newline> regulation of membrane potential in photoreceptor cell ; GO:0016057 | inferred from direct assay <newline> determination of left/right symmetry ; GO:0007368 | inferred from mutant phenotype <newline> regulation of actin cytoskeleton organization ; GO:0032956 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from direct assay <newline> fusome ; GO:0045169 | NOT inferred from direct assay <newline> subapical complex ; GO:0035003 | traceable author statement <newline> cytoplasm ; GO:0005737 | non-traceable author statement <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> adherens junction ; GO:0005912 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> cell cortex ; GO:0005938 | inferred from direct assay <newline> spindle ; GO:0005819 | colocalizes_with inferred from direct assay <newline> actin filament ; GO:0005884 | colocalizes_with inferred from direct assay <newline> extrinsic to membrane ; GO:0019898 | inferred from electronic annotation with InterPro:IPR000798, InterPro:IPR008954, InterPro:IPR011174, InterPro:IPR011259","protein binding ; GO:0005515 | inferred from physical interaction with Mer <newline> cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity <newline> actin binding ; GO:0003779 | non-traceable author statement <newline> cytoskeletal protein binding ; GO:0008092 | inferred from electronic annotation with InterPro:IPR000798, InterPro:IPR008954, InterPro:IPR011174, InterPro:IPR011259"]
[null,"FBgn0019968","Kinesin-73","Khc-73","The gene Kinesin-73 is referred to in FlyBase by the symbol Dmel\\Khc-73 (CG8183, FBgn0019968). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11403283..11419743. It has the cytological map location 52A6-52A10. Based on sequence similarity, it is predicted to have molecular function</span>: microtubule motor activity; microtubule binding. There is experimental evidence that it is involved in the biological process</span>: establishment of spindle orientation. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity with UniProtKB:Q9NQT8 <newline> microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity <newline> establishment of spindle orientation ; GO:0051294 | inferred from mutant phenotype","kinesin complex ; GO:0005871 | inferred from sequence or structural similarity with UniProtKB:Q9NQT8 <newline> kinesin complex ; GO:0005871 | inferred from sequence or structural similarity <newline> astral microtubule ; GO:0000235 | colocalizes_with inferred from direct assay","microtubule binding ; GO:0008017 | inferred from sequence or structural similarity with UniProtKB:Q9NQT8 <newline> microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity with UniProtKB:Q9NQT8 <newline> microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821"]
[null,"FBgn0020278","locomotion defects","loco","The gene locomotion defects is referred to in FlyBase by the symbol Dmel\\loco (CG5248, FBgn0020278). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:18445690..18465082. It has the cytological map location 94B6-94B8. There is experimental evidence that it has the molecular function</span>: G-protein alpha-subunit binding; GTPase activator activity. There is experimental evidence that it is involved in the biological process</span>: regulation of G-protein coupled receptor protein signaling pathway; glial cell differentiation; asymmetric neuroblast division; asymmetric protein localization; dorsal/ventral axis specification, ovarian follicular epithelium; establishment of glial blood-brain barrier; cytoplasmic transport, nurse cell to oocyte; cortical actin cytoskeleton organization; septate junction assembly; ventral cord development. 34 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; yolk; embryonic head; embryonic glial cell; neuroblast; embryonic midgut; egg; longitudinal connective; embryonic foregut; dorsal appendage. It has 4 annotated transcripts and 4 annotated polypeptides.","glial cell differentiation ; GO:0010001 | inferred from mutant phenotype <newline> regulation of G-protein coupled receptor protein signaling pathway ; GO:0008277 | non-traceable author statement <newline> cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | inferred from mutant phenotype <newline> dorsal/ventral axis specification, ovarian follicular epithelium ; GO:0008069 | inferred from mutant phenotype <newline> asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype <newline> regulation of G-protein coupled receptor protein signaling pathway ; GO:0008277 | inferred from genetic interaction with raps <newline> asymmetric protein localization ; GO:0008105 | inferred from mutant phenotype <newline> septate junction assembly ; GO:0019991 | inferred from mutant phenotype <newline> establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype <newline> ventral cord development ; GO:0007419 | inferred from mutant phenotype <newline> cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR003109, InterPro:IPR003116","plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> apical cortex ; GO:0045179 | inferred from direct assay","GTPase activator activity ; GO:0005096 | inferred from direct assay <newline> G-protein alpha-subunit binding ; GO:0001965 | inferred from physical interaction with G-iÎ±65A <newline> receptor signaling protein activity ; GO:0005057 | inferred from electronic annotation with InterPro:IPR003116"]
[null,"FBgn0028421","Kinesin associated protein 3","Kap3","The gene Kinesin associated protein 3 is referred to in FlyBase by the symbol Dmel\\Kap3 (CG11759, FBgn0028421). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11228220..11234117. It has the cytological map location 10B3. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: anterograde axon cargo transport; sensory cilium assembly. 12 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides.","microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity with NCBI_gi:861365 <newline> sperm axoneme assembly ; GO:0007288 | NOT inferred from mutant phenotype <newline> sensory cilium assembly ; GO:0035058 | inferred from mutant phenotype <newline> anterograde axon cargo transport ; GO:0008089 | inferred from mutant phenotype","kinesin complex ; GO:0005871 | inferred from sequence or structural similarity with NCBI_gi:861365 <newline> kinesin II complex ; GO:0016939 | inferred from direct assay <newline> kinesin II complex ; GO:0016939 | inferred from sequence or structural similarity with UniProtKB:P70188","microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity with NCBI_gi:861365 <newline> protein binding ; GO:0005515 | inferred from physical interaction with Apc2 <newline> kinesin binding ; GO:0019894 | inferred from electronic annotation with InterPro:IPR008658"]
[null,"FBgn0028968","gamma-coatomer protein","gammaCop","The gene ?-coatomer protein is referred to in FlyBase by the symbol Dmel\\?Cop (CG1528, FBgn0028968). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27397865..27401429. It has the cytological map location 100C6. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; structural molecule activity. There is experimental evidence that it is involved in the biological process</span>: cytokinesis; regulation of lipid storage; protein secretion; open tracheal system development; branch fusion, open tracheal system; lumen formation, open tracheal system; chitin-based embryonic cuticle biosynthetic process; phagocytosis, engulfment. 33 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; embryonic/larval lateral trunk; embryonic/larval dorsal trunk; embryonic nervous system; embryonic/larval dorsal branch; denticle belt. It has 3 annotated transcripts and 3 annotated polypeptides.","retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | non-traceable author statement <newline> cytokinesis ; GO:0000910 | inferred from mutant phenotype <newline> retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity with UniProtKB:P53620 <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> regulation of lipid storage ; GO:0010883 | inferred from direct assay <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype <newline> branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype <newline> protein secretion ; GO:0009306 | inferred from mutant phenotype <newline> intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR009028, InterPro:IPR013040, InterPro:IPR013041, InterPro:IPR014863, InterPro:IPR015873","COPI vesicle coat ; GO:0030126 | non-traceable author statement <newline> COPI vesicle coat ; GO:0030126 | inferred from sequence or structural similarity with UniProtKB:P53620 <newline> Golgi apparatus ; GO:0005794 | inferred from direct assay","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR009028, InterPro:IPR013040, InterPro:IPR013041, InterPro:IPR014863, InterPro:IPR015873 <newline> structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR013040, InterPro:IPR014863"]
[null,"FBgn0034743","Ribosomal protein S16","RpS16","The gene Ribosomal protein S16 is referred to in FlyBase by the symbol Dmel\\RpS16 (CG4046, FBgn0034743). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18493626..18495506. It has the cytological map location 58F1. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of ribosome. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle elongation; mitotic spindle organization. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","translation ; GO:0006412 | inferred from sequence or structural similarity with HGNC_gene:RPS16; HGNC:10396; OMIM:603675 <newline> mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype","lipid particle ; GO:0005811 | inferred from direct assay <newline> cytosolic small ribosomal subunit ; GO:0022627 | inferred from sequence or structural similarity with HGNC_gene:RPS16; HGNC:10396; OMIM:603675","structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with HGNC_gene:RPS16; HGNC:10396; OMIM:603675"]
[null,"FBgn0035162","-","CG13900","This gene is referred to in FlyBase by the symbol Dmel\\CG13900 (CG13900, FBgn0035162). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:826710..833402. It has the cytological map location 61D2. Based on sequence similarity, it is predicted to have molecular function</span>: damaged DNA binding. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle organization. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","nuclear mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with SGD_LOCUS:RSE1; SGD:S0004513 AND inferred from sequence or structural similarity with protein_id:CAB56791 <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype <newline> nuclear mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011|GO:0071013","small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with SGD_LOCUS:RSE1; SGD:S0004513 AND inferred from sequence or structural similarity with protein_id:CAB56791 <newline> U2 snRNP ; GO:0005686 | inferred from sequence or structural similarity with SGD_LOCUS:RSE1; SGD:S0004513 AND inferred from sequence or structural similarity with protein_id:CAB56791 <newline> precatalytic spliceosome ; GO:0071011 | inferred from direct assay <newline> catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay","damaged DNA binding ; GO:0003684 | inferred from sequence or structural similarity with EMBL:AF159853; protein_id:AAD42230.1"]
[null,"FBgn0040232","CENP-meta","cmet","The gene CENP-meta is referred to in FlyBase by the symbol Dmel\\cmet (CG6392, FBgn0040232). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:11260823..11269179. It has the cytological map location 32E2. Based on sequence similarity, it is predicted to have molecular function</span>: plus-end-directed microtubule motor activity; microtubule motor activity. There is experimental evidence that it is involved in the biological process</span>: mitotic metaphase plate congression; mitotic spindle organization; cell cycle. 6 alleles are reported. The phenotypes of these alleles are annotated with: spindle microtubule; mitotic cell cycle; condensed nuclear chromosome; spindle pole; spermatocyte; astral microtubule. It has one annotated transcript and one annotated polypeptide.","mitotic metaphase plate congression ; GO:0007080 | non-traceable author statement <newline> mitotic metaphase plate congression ; GO:0007080 | inferred from mutant phenotype <newline> microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity <newline> cell cycle ; GO:0007049 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype <newline> microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821","chromosome, centromeric region ; GO:0000775 | non-traceable author statement <newline> kinetochore ; GO:0000776 | non-traceable author statement <newline> kinetochore ; GO:0000776 | inferred from direct assay <newline> kinesin complex ; GO:0005871 | inferred from sequence or structural similarity <newline> outer kinetochore of condensed chromosome ; GO:0000940 | non-traceable author statement <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","microtubule motor activity ; GO:0003777 | non-traceable author statement <newline> plus-end-directed microtubule motor activity ; GO:0008574 | inferred from sequence or structural similarity with HGNC_gene:CENPE; HGNC:1856; OMIM:117143 <newline> microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity <newline> microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity with EMBL:AF027728 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752, InterPro:IPR019821"]
[null,"FBgn0082582","tropomodulin","tmod","The gene tropomodulin is referred to in FlyBase by the symbol Dmel\\tmod (CG1539, FBgn0082582). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26358336..26404627. It has the cytological map location 99F7-99F8. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: cytoskeleton organization. 24 alleles are reported. The phenotypes of these alleles are annotated with: striated muscle thin filament; indirect flight muscle. It has 12 annotated transcripts and 12 annotated polypeptides.","cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity with MGD:Tmod1; MGI:MGI:98775","cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR004934","actin binding ; GO:0003779 | inferred from sequence or structural similarity <newline> tropomyosin binding ; GO:0005523 | non-traceable author statement <newline> tropomyosin binding ; GO:0005523 | inferred from electronic annotation with InterPro:IPR004934"]
[null,"FBgn0243512","puckered","puc","The gene puckered is referred to in FlyBase by the symbol Dmel\\puc (CG7850, FBgn0243512). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3931057..3948023. It has the cytological map location 84E12-84E11. There is experimental evidence that it has the molecular function</span>: JUN kinase phosphatase activity; phosphoprotein phosphatase activity. There is experimental evidence for 20 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; organ development; organ morphogenesis; regulation of biological process; actin filament-based process; ovarian follicle cell development; regulation of developmental process; response to stress; organelle organization. 54 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; egg; cuticle; peripheral nervous system; external compound sense organ; adult segment; nervous system; chorion; adult mesothoracic segment; cuticular specialization. It has one annotated transcript and one annotated polypeptide.","imaginal disc eversion ; GO:0007561 | inferred from mutant phenotype <newline> imaginal disc fusion ; GO:0046528 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> epidermis development ; GO:0008544 | inferred from mutant phenotype <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> JNK cascade ; GO:0007254 | non-traceable author statement <newline> suture of dorsal opening ; GO:0007396 | non-traceable author statement <newline> JNK cascade ; GO:0007254 | inferred from mutant phenotype <newline> actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype <newline> protein amino acid dephosphorylation ; GO:0006470 | inferred from direct assay AND inferred from sequence or structural similarity <newline> protein amino acid dephosphorylation ; GO:0006470 | non-traceable author statement <newline> JNK cascade ; GO:0007254 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> wound healing ; GO:0042060 | inferred from expression pattern <newline> negative regulation of JNK cascade ; GO:0046329 | traceable author statement <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> response to oxidative stress ; GO:0006979 | inferred from mutant phenotype <newline> wound healing ; GO:0042060 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> negative regulation of JNK cascade ; GO:0046329 | non-traceable author statement <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> micropyle formation ; GO:0046844 | inferred from mutant phenotype <newline> wound healing ; GO:0042060 | inferred from direct assay <newline> dorsal closure ; GO:0007391 | non-traceable author statement <newline> ommatidial rotation ; GO:0016318 | non-traceable author statement <newline> establishment of planar polarity ; GO:0001736 | non-traceable author statement <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Pvr <newline> regulation of G2/M transition of mitotic cell cycle ; GO:0010389 | inferred from mutant phenotype","Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay","MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | non-traceable author statement <newline> JUN kinase phosphatase activity ; GO:0008579 | inferred from mutant phenotype <newline> phosphoprotein phosphatase activity ; GO:0004721 | inferred from direct assay <newline> protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity <newline> protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from sequence or structural similarity <newline> JUN kinase phosphatase activity ; GO:0008579 | non-traceable author statement <newline> JUN kinase phosphatase activity ; GO:0008579 | traceable author statement <newline> protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement <newline> MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | traceable author statement <newline> protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130"]
[null,"FBgn0260003","Dystrophin","Dys","The gene Dystrophin is referred to in FlyBase by the symbol Dmel\\Dys (CG34157, FBgn0260003). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:15286810..15421117. It has the cytological map location 92A5-92A10. There is experimental evidence that it has the molecular function</span>: WW domain binding. There is experimental evidence that it is involved in the biological process</span>: neuromuscular synaptic transmission; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived wing vein specification; regulation of short-term neuronal synaptic plasticity; muscle homeostasis; establishment of cell polarity. 40 alleles are reported. The phenotypes of these alleles are annotated with: posterior crossvein; presynaptic active zone; terminal button. It has 8 annotated transcripts and 8 annotated polypeptides.","imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> muscle organ development ; GO:0007517 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> neuromuscular synaptic transmission ; GO:0007274 | inferred from direct assay <newline> regulation of short-term neuronal synaptic plasticity ; GO:0048172 | inferred from direct assay <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype <newline> establishment of cell polarity ; GO:0030010 | inferred from mutant phenotype <newline> muscle cell homeostasis ; GO:0046716 | inferred from mutant phenotype","cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity <newline> dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from sequence or structural similarity with HGNC_gene:DMD; HGNC:2928; OMIM:300377 AND inferred from sequence or structural similarity with HGNC_gene:DRP2; HGNC:3032; OMIM:300052 AND inferred from sequence or structural similarity with HGNC_gene:UTRN; HGNC:12635; OMIM:128240 <newline> dystrophin-associated glycoprotein complex ; GO:0016010 | non-traceable author statement <newline> dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from sequence or structural similarity <newline> cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from physical interaction with Dg","structural molecule activity ; GO:0005198 | inferred from sequence or structural similarity <newline> structural constituent of muscle ; GO:0008307 | inferred from sequence or structural similarity with HGNC_gene:DMD; HGNC:2928; OMIM:300377 AND inferred from sequence or structural similarity with HGNC_gene:DRP2; HGNC:3032; OMIM:300052 AND inferred from sequence or structural similarity with HGNC_gene:UTRN; HGNC:12635; OMIM:128240 <newline> cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity <newline> actin binding ; GO:0003779 | inferred from sequence or structural similarity <newline> actin binding ; GO:0003779 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> structural constituent of muscle ; GO:0008307 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> WW domain binding ; GO:0050699 | inferred from physical interaction with Dg <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433 <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR011992"]
[null,"FBgn0035411","Girdin","Girdin","The gene Girdin is referred to in FlyBase by the symbol Dmel\\Girdin (CG12734, FBgn0035411). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: microtubule binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of cell size; actin filament organization. 8 alleles are reported. The phenotype of these alleles is annotated with: wing vein. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: HOOK. Gene sequence location is 3L:3178934..3185287.","microtubule cytoskeleton organization ; GO:0000226 | inferred from electronic annotation with InterPro:IPR008636 <newline> positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR008636","microtubule binding ; GO:0008017 | inferred from electronic annotation with InterPro:IPR008636"]
[null,"FBgn0035120","wee Augmin","wac","The gene wee Augmin is referred to in FlyBase by the symbol Dmel\\wac (CG13879, FBgn0035120). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: protein binding; microtubule binding. There is experimental evidence that it is involved in the biological process</span>: female meiosis; mitotic spindle organization; cytoplasmic microtubule organization; spindle assembly; cell division. 7 alleles are reported. The phenotypes of these alleles are annotated with: eye; macrochaeta; adult cuticle; spindle. It has 2 annotated transcripts and 2 annotated polypeptides. Gene sequence location is 3L:258350..259097.","cell division ; GO:0051301 | inferred from mutant phenotype <newline> spindle assembly ; GO:0051225 | inferred from mutant phenotype <newline> female meiosis ; GO:0007143 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype <newline> cytoplasmic microtubule organization ; GO:0031122 | inferred from mutant phenotype","protein complex ; GO:0043234 | inferred from direct assay inferred from genetic interaction with dgt2 <newline> spindle ; GO:0005819 | inferred from direct assay <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with dgt2 <newline> microtubule binding ; GO:0008017 | inferred from direct assay"]
[null,"FBgn0013812","Dynein heavy chain at 93AB","Dhc93AB","The gene Dynein heavy chain at 93AB is referred to in FlyBase by the symbol Dmel\\Dhc93AB (CG3723, FBgn0013812). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled; motor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: microtubule-based movement. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: ATPase, AAA+ type, core; ATPase, AAA-5; Dynein heavy chain; Dynein heavy chain, N-terminal domain-1; Dynein heavy chain, N-terminal domain-2. Gene sequence location is 3R:16850741..16868141.","microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity <newline> microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR004273","microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity <newline> axonemal dynein complex ; GO:0005858 | inferred from sequence or structural similarity with EMBL:Z83813; protein_id:CAB06067 <newline> microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity with SGD_LOCUS:DYN1; SGD:S0001762","ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity <newline> motor activity ; GO:0003774 | inferred from sequence or structural similarity with SGD_LOCUS:DYN1; SGD:S0001762 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR011704 <newline> ATPase activity ; GO:0016887 | inferred from electronic annotation with InterPro:IPR011704 <newline> microtubule motor activity ; GO:0003777 | inferred from electronic annotation with InterPro:IPR004273"]
[null,"FBgn0038167","lkb1","lkb1","The gene lkb1 is referred to in FlyBase by the symbol Dmel\\lkb1 (CG9374, FBgn0038167). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function</span>: protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: border follicle cell delamination; dorsal closure; regulation of JNK cascade; oocyte microtubule cytoskeleton organization; pole plasm oskar mRNA localization; mitotic spindle organization; asymmetric neuroblast division; positive regulation of apoptosis. 23 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; organelle; adult segment; thoracic segment; spindle; anatomical structure; peripheral nervous system; intracellular organelle part; spindle microtubule; adult. It has 9 annotated transcripts and 9 annotated polypeptides. Protein features are: Calcium/calmodulin-dependent protein kinase-like; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase STK; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain. Gene sequence location is 3R:9502271..9505152.","protein phosphorylation ; GO:0006468 | non-traceable author statement <newline> oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype <newline> establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement <newline> pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype <newline> asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype <newline> border follicle cell delamination ; GO:0030709 | inferred from mutant phenotype <newline> positive regulation of apoptosis ; GO:0043065 | inferred from direct assay <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> regulation of JNK cascade ; GO:0046328 | inferred from direct assay <newline> protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR008271, InterPro:IPR015735, InterPro:IPR017441, InterPro:IPR017442","nucleus ; GO:0005634 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay","protein kinase activity ; GO:0004672 | non-traceable author statement <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR002290, InterPro:IPR008271, InterPro:IPR015735 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR015735, InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0010501","Death caspase-1","Dcp-1","The gene Death caspase-1 is referred to in FlyBase by the symbol Dmel\\Dcp-1 (CG5370, FBgn0010501). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: cysteine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: apoptosis; ovarian nurse cell to oocyte transport; cleavage of lamin; actin cytoskeleton organization; embryonic development; autophagic cell death; developmental programmed cell death; salivary gland cell autophagic cell death. 38 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; eye; embryonic/larval digestive system; gonad; trachea; imaginal disc; outer photoreceptor cell; egg chamber; melanotic mass; pigment cell. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase C14, ICE, catalytic subunit p20; Peptidase C14, ICE, catalytic subunit p20, active site; Peptidase C14, caspase catalytic; Peptidase C14, caspase non-catalytic subunit p10; Peptidase C14, caspase precursor p45; Peptidase C14, caspase precursor p45, core. Gene sequence location is 2R:19438838..19441079.","apoptosis ; GO:0006915 | inferred from direct assay <newline> embryo development ; GO:0009790 | inferred from mutant phenotype <newline> actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype <newline> cleavage of lamin ; GO:0006922 | inferred from mutant phenotype <newline> ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype <newline> actin filament organization ; GO:0007015 | traceable author statement <newline> cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | traceable author statement <newline> nurse cell apoptosis ; GO:0045476 | traceable author statement <newline> apoptosis ; GO:0006915 | non-traceable author statement <newline> apoptosis ; GO:0006915 | traceable author statement <newline> proteolysis ; GO:0006508 | traceable author statement <newline> multicellular organismal development ; GO:0007275 | traceable author statement <newline> ovarian nurse cell to oocyte transport ; GO:0007300 | traceable author statement <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> apoptosis ; GO:0006915 | inferred from mutant phenotype <newline> developmental programmed cell death ; GO:0010623 | inferred from mutant phenotype","caspase complex ; GO:0008303 | non-traceable author statement","cysteine-type endopeptidase activity ; GO:0004197 | inferred from direct assay <newline> cysteine-type endopeptidase activity ; GO:0004197 | inferred from direct assay AND inferred from sequence or structural similarity <newline> cysteine-type endopeptidase activity ; GO:0004197 | traceable author statement <newline> cysteine-type endopeptidase activity ; GO:0004197 | non-traceable author statement <newline> cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity"]
[null,"FBgn0262114","Ran-binding protein M","RanBPM","The gene Ran-binding protein M is referred to in FlyBase by the symbol Dmel\\RanBPM (CG42236, FBgn0262114). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: Ran GTPase binding. There is experimental evidence that it is involved in the biological process</span>: larval feeding behavior; ovarian follicle cell-cell adhesion; germ-line stem-cell niche homeostasis; cytoskeleton organization; dorsal appendage formation. 14 alleles are reported. The phenotypes of these alleles are annotated with: terminal filament; ovary; germline stem cell; germarium cap cell; egg chamber. It has 4 annotated transcripts and 4 annotated polypeptides. Gene sequence location is 2R:6317217..6324086.","germ-line stem-cell niche homeostasis ; GO:0060250 | inferred from mutant phenotype <newline> cytoskeleton organization ; GO:0007010 | inferred from direct assay <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> ovarian follicle cell-cell adhesion ; GO:0007299 | inferred from mutant phenotype <newline> larval feeding behavior ; GO:0030536 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay","Ran GTPase binding ; GO:0008536 | inferred from sequence or structural similarity with HGNC_gene:RANBP9; HGNC:13727"]
[]
["Cellular Transport/ Phagocytosis"]
[null,"FBgn0040890","kish","ksh","The gene kish is referred to in FlyBase by the symbol Dmel\\ksh (CG14199, FBgn0040890). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: intracellular transport. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Protein of unknown function DUF1242. Gene sequence location is X:19388452..19389011.","intracellular transport ; GO:0046907 | inferred from mutant phenotype","Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay","molecular_function ; GO:0003674 | no biological data available"]
[null,"FBgn0262736","Vacuolar H[+] ATPase subunit 16-1","Vha16-1","The gene Vacuolar H<sup>+</sup> ATPase subunit 16-1 is referred to in FlyBase by the symbol Dmel\\Vha16-1 (CG3161, FBgn0262736). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: hydrogen-exporting ATPase activity, phosphorylative mechanism. There is experimental evidence that it is involved in the biological process</span>: dsRNA transport. 46 alleles are reported. The phenotypes of these alleles are annotated with: macrochaeta; Malpighian tubule. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: ATPase, F0 complex, subunit C; ATPase, F0/V0 complex, subunit C; ATPase, V0 complex, proteolipid subunit C; ATPase, V0 complex, proteolipid subunit C, eukaryotic. Gene sequence location is 2R:2512747..2520633.","proton transport ; GO:0015992 | non-traceable author statement <newline> dsRNA transport ; GO:0033227 | inferred from mutant phenotype <newline> ATP synthesis coupled proton transport ; GO:0015986 | inferred from electronic annotation with InterPro:IPR000245, InterPro:IPR000454, InterPro:IPR002379, InterPro:IPR011555","vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with UniProtKB:P31403 <newline> vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | inferred from sequence or structural similarity with SGD_LOCUS:CUP5; SGD:S0000753 <newline> vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220 | non-traceable author statement <newline> fusome ; GO:0045169 | inferred from direct assay <newline> proton-transporting ATP synthase complex, coupling factor F(o) ; GO:0045263 | inferred from electronic annotation with InterPro:IPR000454","hydrogen-exporting ATPase activity, phosphorylative mechanism ; GO:0008553 | inferred from sequence or structural similarity with UniProtKB:P31403 <newline> hydrogen-exporting ATPase activity, phosphorylative mechanism ; GO:0008553 | inferred from sequence or structural similarity with SGD_LOCUS:CUP5; SGD:S0000753 <newline> hydrogen-exporting ATPase activity, phosphorylative mechanism ; GO:0008553 | non-traceable author statement"]
[null,"FBgn0035141","Cyclophilin-like","Cypl","The gene Cyclophilin-like is referred to in FlyBase by the symbol Dmel\\Cypl (CG13892, FBgn0035141). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: peptidyl-prolyl cis-trans isomerase activity. It is reported to be involved in the biological process</span>: regulation of post-mating oviposition; nuclear mRNA splicing, via spliceosome. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Cyclophilin-like; Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; Peptidyl-prolyl cis-trans isomerase, cyclophilin-type, conserved site. Gene sequence location is 3L:542122..542916.","regulation of post-mating oviposition ; GO:0048042 | non-traceable author statement <newline> nuclear mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011|GO:0071013 <newline> protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002130, InterPro:IPR020892","precatalytic spliceosome ; GO:0071011 | inferred from direct assay <newline> catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay","peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from sequence or structural similarity with UniProtKB:Q9DCY1"]
[null,"FBgn0028471","-","CG5720","This gene is referred to in FlyBase by the symbol Dmel\\CG5720 (FBgn0028471). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding; nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 2 alleles are reported. The phenotypes of these alleles are annotated with: eye; scutellar bristle. It has one annotated transcript and one annotated polypeptide. Protein features are: Zinc finger, CCCH-type. Gene sequence location is 3R:20140382..20144142.","phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype","-","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000571 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000571"]
[null,"FBgn0027054","COP9 complex homolog subunit 4","CSN4","The gene COP9 complex homolog subunit 4 is referred to in FlyBase by the symbol Dmel\\CSN4 (CG8725, FBgn0027054). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: protein binding; promoter binding; NEDD8 activating enzyme activity. There is experimental evidence that it is involved in the biological process</span>: protein deneddylation; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; compound eye photoreceptor cell differentiation; protein stabilization. 8 alleles are reported. The phenotypes of these alleles are annotated with: cephalopharyngeal skeleton; photoreceptor cell. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Proteasome component (PCI) domain; Tetratricopeptide-like helical; Winged helix-turn-helix transcription repressor DNA-binding. Gene sequence location is 2R:3859680..3861604.","protein deneddylation ; GO:0000338 | inferred from mutant phenotype <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype <newline> negative regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032435 | inferred from mutant phenotype <newline> protein stabilization ; GO:0050821 | inferred from mutant phenotype","signalosome ; GO:0008180 | inferred from sequence or structural similarity <newline> signalosome ; GO:0008180 | inferred from mutant phenotype <newline> signalosome ; GO:0008180 | non-traceable author statement <newline> signalosome ; GO:0008180 | traceable author statement <newline> signalosome ; GO:0008180 | inferred from physical interaction with CSN7","NEDD8 activating enzyme activity ; GO:0019781 | inferred from mutant phenotype <newline> protein binding ; GO:0005515 | inferred from physical interaction with CSN7 <newline> promoter binding ; GO:0010843 | inferred from direct assay"]
[null,"FBgn0031437","p16-ARC","p16-ARC","The gene p16-ARC is referred to in FlyBase by the symbol Dmel\\p16-ARC (CG9881, FBgn0031437). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: ARP2/3 complex 16kDa subunit (p16-Arc). Gene sequence location is 2L:2580291..2581114.","phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> regulation of actin filament polymerization ; GO:0030833 | inferred from electronic annotation with InterPro:IPR006789","lamellipodium ; GO:0030027 | inferred from direct assay <newline> cytoskeleton ; GO:0005856 | inferred from electronic annotation with InterPro:IPR006789","actin binding ; GO:0003779 | inferred from sequence or structural similarity"]
[null,"FBgn0011785","BRWD3","BRWD3","The gene BRWD3 is referred to in FlyBase by the symbol Dmel\\BRWD3 (CG31132, FBgn0011785). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:20144741..20154341. It has the cytological map location 95F12-95F13. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 16 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype","-","-"]
[null,"FBgn0066101","LpR1","LpR1","The gene LpR1 is referred to in FlyBase by the symbol Dmel\\LpR1 (CG31094, FBgn0066101). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21567070..21586044. It has the cytological map location 96F1-96F2. There is experimental evidence that it has the molecular function</span>: receptor activity. There is experimental evidence that it is involved in the biological process</span>: receptor-mediated endocytosis. 9 alleles are reported. No phenotypic data is available. It has 7 annotated transcripts and 7 annotated polypeptides.","cholesterol metabolic process ; GO:0008203 | inferred from sequence or structural similarity with UniProtKB:Q99088 <newline> lipoprotein transport ; GO:0042953 | inferred from sequence or structural similarity with UniProtKB:Q99088 <newline> receptor-mediated endocytosis ; GO:0006898 | inferred from mutant phenotype inferred from expression pattern","membrane ; GO:0016020 | inferred from sequence or structural similarity with InterPro:IPR000033","lipoprotein binding ; GO:0008034 | inferred from sequence or structural similarity with UniProtKB:Q99088 <newline> low-density lipoprotein receptor activity ; GO:0005041 | inferred from sequence or structural similarity with UniProtKB:Q99088 <newline> receptor activity ; GO:0004872 | inferred from mutant phenotype inferred from expression pattern <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097"]
[]
["Chitin Binding/Cuticle formation"]
[null,"FBgn0010434","coracle","cora","The gene coracle is referred to in FlyBase by the symbol Dmel\\cora (CG11949, FBgn0010434). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15116570..15131256. It has the cytological map location 56C4. Based on sequence similarity, it is predicted to have molecular function</span>: cytoskeletal protein binding. There is experimental evidence that it is involved in the biological process</span>: embryonic morphogenesis; maintenance of imaginal disc-derived wing hair orientation; regulation of tube size, open tracheal system; establishment of glial blood-brain barrier. 42 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: peripheral nervous system; organ system; nervous system; external compound sense organ; plasma membrane part; integumentary plate; plasma membrane; embryonic head; embryonic dorsal trunk; wing hair; embryonic tracheal system. It has 4 annotated transcripts and 4 annotated polypeptides.","embryonic morphogenesis ; GO:0048598 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | traceable author statement <newline> salivary gland morphogenesis ; GO:0007435 | traceable author statement <newline> septate junction assembly ; GO:0019991 | traceable author statement <newline> protein targeting to membrane ; GO:0006612 | traceable author statement <newline> regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype <newline> maintenance of imaginal disc-derived wing hair orientation ; GO:0035321 | inferred from mutant phenotype <newline> cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity with EMBL:AB019257; protein_id:BAA76625.1 <newline> embryonic development ; GO:0009790 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | non-traceable author statement <newline> cell-cell junction organization ; GO:0045216 | traceable author statement <newline> establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement <newline> establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype","septate junction ; GO:0005918 | inferred from direct assay <newline> fusome ; GO:0045169 | NOT inferred from direct assay <newline> spectrosome ; GO:0045170 | NOT inferred from direct assay <newline> septate junction ; GO:0005918 | traceable author statement <newline> septate junction ; GO:0005918 | non-traceable author statement <newline> cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity with EMBL:AB019257; protein_id:BAA76625.1 <newline> apicolateral plasma membrane ; GO:0016327 | non-traceable author statement","cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity <newline> actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR008379 <newline> structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR008379"]
[null,"FBgn0000568","Ecdysone-induced protein 75B","Eip75B","The gene Ecdysone-induced protein 75B is referred to in FlyBase by the symbol Dmel\\Eip75B (CG8127, FBgn0000568). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:17945063..18052698. It has the cytological map location 75A10-75B6. There is experimental evidence that it has the molecular function</span>: heme binding. There is experimental evidence that it is involved in the biological process</span>: molting cycle, chitin-based cuticle; antimicrobial humoral response; ecdysis, chitin-based cuticle; regulation of ecdysteroid metabolic process. 136 alleles are reported. The phenotypes of these alleles are annotated with: eye; midgut chamber 3; midgut constriction 1; larval anterior spiracle; wing; mouth hooks. It has 4 annotated transcripts and 4 annotated polypeptides.","ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | non-traceable author statement <newline> ecdysis, chitin-based cuticle ; GO:0018990 | inferred from mutant phenotype <newline> molting cycle, chitin-based cuticle ; GO:0007591 | inferred from mutant phenotype <newline> regulation of ecdysteroid metabolic process ; GO:0007553 | inferred from mutant phenotype <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> molting cycle, chitin-based cuticle ; GO:0007591 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> oogenesis ; GO:0048477 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000324, InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR001723, InterPro:IPR003079, InterPro:IPR008946, InterPro:IPR013088","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:U09504 <newline> nucleus ; GO:0005634 | non-traceable author statement","ligand-dependent nuclear receptor activity ; GO:0004879 | inferred from sequence or structural similarity with EMBL:U09504 <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from sequence or structural similarity with EMBL:U09504 <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | non-traceable author statement <newline> heme binding ; GO:0020037 | inferred from direct assay <newline> steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR000536, InterPro:IPR008946 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR008946, InterPro:IPR013088"]
[null,"FBgn0026077","Gasp","Gasp","The gene Gasp is referred to in FlyBase by the symbol Dmel\\Gasp (CG10287, FBgn0026077). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1914951..1926609. It has the cytological map location 83D4. Based on sequence similarity, it is predicted to have molecular function</span>: chitin binding; structural constituent of peritrophic membrane. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: chitin metabolic process. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557","extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557","chitin binding ; GO:0008061 | non-traceable author statement <newline> structural constituent of peritrophic membrane ; GO:0016490 | inferred from sequence or structural similarity with EMBL:AF000606 <newline> chitin binding ; GO:0008061 | inferred from reviewed computational analysis <newline> chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557"]
[null,"FBgn0028968","gamma-coatomer protein","gammaCop","The gene ?-coatomer protein is referred to in FlyBase by the symbol Dmel\\?Cop (CG1528, FBgn0028968). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27397865..27401429. It has the cytological map location 100C6. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; structural molecule activity. There is experimental evidence that it is involved in the biological process</span>: cytokinesis; regulation of lipid storage; protein secretion; open tracheal system development; branch fusion, open tracheal system; lumen formation, open tracheal system; chitin-based embryonic cuticle biosynthetic process; phagocytosis, engulfment. 33 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; embryonic/larval lateral trunk; embryonic/larval dorsal trunk; embryonic nervous system; embryonic/larval dorsal branch; denticle belt. It has 3 annotated transcripts and 3 annotated polypeptides.","retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | non-traceable author statement <newline> cytokinesis ; GO:0000910 | inferred from mutant phenotype <newline> retrograde vesicle-mediated transport, Golgi to ER ; GO:0006890 | inferred from sequence or structural similarity with UniProtKB:P53620 <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> regulation of lipid storage ; GO:0010883 | inferred from direct assay <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> lumen formation, open tracheal system ; GO:0035149 | inferred from mutant phenotype <newline> branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype <newline> protein secretion ; GO:0009306 | inferred from mutant phenotype <newline> intracellular protein transport ; GO:0006886 | inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR009028, InterPro:IPR013040, InterPro:IPR013041, InterPro:IPR014863, InterPro:IPR015873","COPI vesicle coat ; GO:0030126 | non-traceable author statement <newline> COPI vesicle coat ; GO:0030126 | inferred from sequence or structural similarity with UniProtKB:P53620 <newline> Golgi apparatus ; GO:0005794 | inferred from direct assay","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR009028, InterPro:IPR013040, InterPro:IPR013041, InterPro:IPR014863, InterPro:IPR015873 <newline> structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR013040, InterPro:IPR014863"]
[null,"FBgn0053196","dumpy","dp","The gene dumpy is referred to in FlyBase by the symbol Dmel\\dp (CG33196, FBgn0053196). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:4479471..4591963. It has the cytological map location 24F4-25A1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: 4 iron, 4 sulfur cluster binding; serine-type endopeptidase inhibitor activity; endonuclease activity; calcium ion binding. There is experimental evidence that it is involved in the biological process</span>: apposition of dorsal and ventral imaginal disc-derived wing surfaces; chitin-based cuticle attachment to epithelium; open tracheal system development; chitin-based embryonic cuticle biosynthetic process. 270 alleles are reported. The phenotypes of these alleles are annotated with 20 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; embryonic/larval tracheal system; portion of tissue; peripheral nervous system; nervous system; lateral trunk posterior branch; adult trachea; embryonic tracheal system; tracheal system. It has one annotated transcript and one annotated polypeptide.","chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype <newline> chitin-based cuticle attachment to epithelium ; GO:0040005 | inferred from mutant phenotype <newline> apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype","proteinaceous extracellular matrix ; GO:0005578 | non-traceable author statement","endonuclease activity ; GO:0004519 | inferred from electronic annotation with InterPro:IPR003651 <newline> 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR003651 <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 <newline> serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR000737"]
[null,"FBgn0086687","desat1","desat1","The gene desat1 is referred to in FlyBase by the symbol Dmel\\desat1 (CG5887, FBgn0086687). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8265322..8273338. It has the cytological map location 87B10-87B11. Based on sequence similarity, it is predicted to have molecular function</span>: stearoyl-CoA 9-desaturase activity. There is experimental evidence that it is involved in the biological process</span>: cuticle hydrocarbon biosynthetic process; pheromone biosynthetic process. 57 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides.","cuticle hydrocarbon biosynthetic process ; GO:0006723 | inferred from mutant phenotype <newline> pheromone biosynthetic process ; GO:0042811 | inferred from mutant phenotype <newline> fatty acid biosynthetic process ; GO:0006633 | non-traceable author statement <newline> oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR005804, InterPro:IPR015876 <newline> lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR005804","lipid particle ; GO:0005811 | inferred from direct assay","stearoyl-CoA 9-desaturase activity ; GO:0004768 | inferred from sequence or structural similarity with EMBL:AF097514; protein_id:AAD29870.1 <newline> stearoyl-CoA 9-desaturase activity ; GO:0004768 | non-traceable author statement"]
[null,"FBgn0260653","serpentine","serp","The gene serpentine is referred to in FlyBase by the symbol Dmel\\serp (CG32209, FBgn0260653). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19694077..19701109. It has the cytological map location 76C2. There is experimental evidence that it has the molecular function</span>: chitin binding; chitin deacetylase activity. There is experimental evidence that it is involved in the biological process</span>: open tracheal system development; regulation of tube length, open tracheal system. 16 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; embryonic/larval trachea; cuticle; embryonic/larval dorsal trunk; embryonic/larval tracheal system. It has one annotated transcript and one annotated polypeptide.","regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557","cytoplasm ; GO:0005737 | inferred from direct assay <newline> extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557","chitin binding ; GO:0008061 | inferred from mutant phenotype <newline> chitin deacetylase activity ; GO:0004099 | inferred from mutant phenotype"]
[null,"FBgn0066365","dusky-like","dyl","The gene dusky-like is referred to in FlyBase by the symbol Dmel\\dyl (CG15013, FBgn0066365). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of chitin-based cuticle. There is experimental evidence that it is involved in the biological process</span>: regulation of embryonic cell shape; cell-matrix adhesion; actin filament organization. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Endoglin/CD105 antigen. Gene sequence location is 3L:4293995..4307711.","regulation of embryonic cell shape ; GO:0016476 | inferred from mutant phenotype <newline> cell-matrix adhesion ; GO:0007160 | inferred from mutant phenotype <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype","filamentous actin ; GO:0031941 | inferred from direct assay <newline> apical cortex ; GO:0045179 | inferred from direct assay","structural constituent of chitin-based cuticle ; GO:0005214 | inferred from sequence or structural similarity with dy"]
[]
[]
["Mechanosensation/Ion channel"]
[null,"FBgn0000536","easily shocked","eas","The gene easily shocked is referred to in FlyBase by the symbol Dmel\\eas (CG3525, FBgn0000536). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16172360..16179654. It has the cytological map location 14B7. There is experimental evidence that it has the molecular function</span>: ethanolamine kinase activity. There is experimental evidence that it is involved in the biological process</span>: response to mechanical stimulus; asymmetric neuroblast division; brain development; mushroom body development; mechanosensory behavior. 26 alleles are reported. The phenotypes of these alleles are annotated with: mushroom body beta'-lobe; calyx of mushroom body; mushroom body beta-lobe; mushroom body alpha-lobe; mushroom body alpha'-lobe. It has 5 annotated transcripts and 5 annotated polypeptides.","brain development ; GO:0007420 | inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | traceable author statement <newline> mushroom body development ; GO:0016319 | traceable author statement <newline> associative learning ; GO:0008306 | traceable author statement <newline> habituation ; GO:0046959 | traceable author statement <newline> mushroom body development ; GO:0016319 | inferred from mutant phenotype <newline> phosphorylation ; GO:0016310 | non-traceable author statement <newline> mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype <newline> response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype <newline> phosphatidylethanolamine biosynthetic process ; GO:0006646 | non-traceable author statement <newline> asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype <newline> response to mechanical stimulus ; GO:0009612 | inferred from genetic interaction with kcc","-","ethanolamine kinase activity ; GO:0004305 | inferred from direct assay <newline> ethanolamine kinase activity ; GO:0004305 | non-traceable author statement <newline> choline kinase activity ; GO:0004103 | non-traceable author statement <newline> choline kinase activity ; GO:0004103 | traceable author statement"]
[null,"FBgn0005564","Shaker cognate l","Shal","The gene Shaker cognate l is referred to in FlyBase by the symbol Dmel\\Shal (CG9262, FBgn0005564). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19561538..19577680. It has the cytological map location 76B7-76B8. There is experimental evidence that it has the molecular function</span>: A-type (transient outward) potassium channel activity. It is reported to be involved in the biological process</span>: potassium ion transport. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","potassium ion transport ; GO:0006813 | non-traceable author statement <newline> potassium ion transport ; GO:0006813 | traceable author statement <newline> transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821 <newline> potassium ion transport ; GO:0006813 | inferred from electronic annotation with InterPro:IPR003091, InterPro:IPR003131, InterPro:IPR003968, InterPro:IPR003975","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> integral to membrane ; GO:0016021 | non-traceable author statement <newline> voltage-gated potassium channel complex ; GO:0008076 | traceable author statement <newline> voltage-gated potassium channel complex ; GO:0008076 | inferred from electronic annotation with InterPro:IPR003091, InterPro:IPR003131, InterPro:IPR003968, InterPro:IPR003975","voltage-gated potassium channel activity ; GO:0005249 | non-traceable author statement <newline> voltage-gated potassium channel activity ; GO:0005249 | traceable author statement <newline> A-type (transient outward) potassium channel activity ; GO:0005250 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000210, InterPro:IPR011333"]
[null,"FBgn0011286","Ryanodine receptor 44F","Rya-r44F","The gene Ryanodine receptor 44F is referred to in FlyBase by the symbol Dmel\\Rya-r44F (CG10844, FBgn0011286). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4747896..4775602. It has the cytological map location 44F1-44F2. Based on sequence similarity, it is predicted to have molecular function</span>: ryanodine-sensitive calcium-release channel activity. There is experimental evidence that it is involved in the biological process</span>: muscle contraction. 10 alleles are reported. The phenotypes of these alleles are annotated with: larva; larval head; embryonic/larval dorsal vessel; embryonic muscle system; embryonic/larval visceral muscle; embryonic/larval muscle system. It has 4 annotated transcripts and 4 annotated polypeptides.","calcium ion transport ; GO:0006816 | traceable author statement <newline> muscle contraction ; GO:0006936 | inferred from mutant phenotype <newline> cellular calcium ion homeostasis ; GO:0006874 | inferred from electronic annotation with InterPro:IPR009460 <newline> calcium ion transport ; GO:0006816 | inferred from electronic annotation with InterPro:IPR000699 <newline> transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005821","integral to membrane ; GO:0016021 | non-traceable author statement <newline> endoplasmic reticulum membrane ; GO:0005789 | non-traceable author statement <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay <newline> integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR009460","ryanodine-sensitive calcium-release channel activity ; GO:0005219 | traceable author statement <newline> ryanodine-sensitive calcium-release channel activity ; GO:0005219 | inferred from sequence or structural similarity with EMBL:U50465 <newline> ryanodine-sensitive calcium-release channel activity ; GO:0005219 | non-traceable author statement <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR011992"]
[null,"FBgn0015541","slamdance","sda","The gene slamdance is referred to in FlyBase by the symbol Dmel\\sda (CG5518, FBgn0015541). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:22741455..22771035. It has the cytological map location 97D7-97D9. Based on sequence similarity, it is predicted to have molecular function</span>: aminopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: response to mechanical stimulus; mechanosensory behavior. 17 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype <newline> response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype <newline> response to mechanical stimulus ; GO:0009612 | inferred from genetic interaction with kcc <newline> proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001930","-","aminopeptidase activity ; GO:0004177 | inferred from sequence or structural similarity with UniProtKB:P15541 <newline> metallopeptidase activity ; GO:0008237 | inferred from electronic annotation with InterPro:IPR014782 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR014782"]
[null,"FBgn0030844","pickpocket 23","ppk23","The gene pickpocket 23 is referred to in FlyBase by the symbol Dmel\\ppk23 (CG8527, FBgn0030844). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:17460819..17463168. It has the cytological map location 16B4. It is reported to have molecular function</span>: sodium channel activity. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype <newline> sodium ion transport ; GO:0006814 | inferred from electronic annotation with InterPro:IPR001873","membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001873","sodium channel activity ; GO:0005272 | non-traceable author statement <newline> sodium channel activity ; GO:0005272 | inferred from electronic annotation with InterPro:IPR001873"]
[null,"FBgn0029174","FK506-binding protein FKBP59","FKBP59","The gene FK506-binding protein FKBP59 is referred to in FlyBase by the symbol Dmel\\FKBP59 (CG4535, FBgn0029174). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: regulation of calcium ion transport; detection of light stimulus involved in visual perception. 6 alleles are reported. The phenotypes of these alleles are annotated with: plasmatocyte; fascicle; embryonic peripheral nervous system; crystal cell. It has one annotated transcript and one annotated polypeptide. Protein features are: Elongated TPR repeat-containing domain; Peptidyl-prolyl cis-trans isomerase, FKBP-type; Tetratricopeptide TPR-1; Tetratricopeptide repeat; Tetratricopeptide repeat-containing; Tetratricopeptide-like helical. Gene sequence location is 2L:9888034..9890119.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> regulation of calcium ion transport ; GO:0051924 | inferred from direct assay <newline> detection of light stimulus involved in visual perception ; GO:0050908 | inferred from physical interaction with inaD inferred from physical interaction with trpl <newline> protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR001179","inaD signaling complex ; GO:0016027 | inferred from physical interaction with inaD","FK506 binding ; GO:0005528 | inferred from sequence or structural similarity <newline> peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from sequence or structural similarity <newline> FK506 binding ; GO:0005528 | inferred from sequence or structural similarity with HGNC_gene:FKBP4; HGNC:3720 <newline> protein binding ; GO:0005515 | inferred from physical interaction with inaD inferred from physical interaction with trpl"]
[null,"FBgn0024944","Octopamine receptor in mushroom bodies","Oamb","The gene Octopamine receptor in mushroom bodies is referred to in FlyBase by the symbol Dmel\\Oamb (CG3856, FBgn0024944). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: octopamine receptor activity. There is experimental evidence that it is involved in the biological process</span>: ovulation; elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger. 24 alleles are reported. The phenotype of these alleles is annotated with: ovariole. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: 7TM GPCR, rhodopsin-like; GPCR, rhodopsin-like superfamily. Gene sequence location is 3R:16514740..16540263.",null,"ovulation ; GO:0030728 | inferred from mutant phenotype <newline> G-protein signaling, coupled to cAMP nucleotide second messenger ; GO:0007188 | NOT inferred from direct assay <newline> elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger ; GO:0051482 | inferred from direct assay <newline> octopamine or tyramine signaling pathway ; GO:0007211 | inferred from sequence or structural similarity","plasma membrane ; GO:0005886 | non-traceable author statement <newline> integral to plasma membrane ; GO:0005887 | inferred by curator from GO:0004989 <newline> integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276","octopamine receptor activity ; GO:0004989 | non-traceable author statement <newline> G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity <newline> octopamine receptor activity ; GO:0004989 | inferred from direct assay"]
[null,"FBgn0014019","Rhodopsin 5","Rh5","The gene Rhodopsin 5 is referred to in FlyBase by the symbol Dmel\\Rh5 (CG5279, FBgn0014019). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12008376..12009846. It has the cytological map location 33B8. There is experimental evidence that it has the molecular function</span>: G-protein coupled photoreceptor activity. There is experimental evidence that it is involved in the biological process</span>: phototransduction; absorption of visible light. 17 alleles are reported. The phenotype of these alleles is annotated with: eye photoreceptor cell. It has one annotated transcript and one annotated polypeptide.","phototransduction ; GO:0007602 | inferred from genetic interaction with ninaE AND inferred from sequence or structural similarity with Rh3 AND inferred from sequence or structural similarity with Rh4 AND inferred from sequence or structural similarity with ninaE <newline> phototransduction ; GO:0007602 | inferred from sequence or structural similarity with EMBL:X80072; protein_id:CAA56378.1 AND inferred from sequence or structural similarity with Rh3 AND inferred from sequence or structural similarity with Rh4 <newline> phototransduction ; GO:0007602 | inferred from genetic interaction with ninaE <newline> UV-A, blue light phototransduction ; GO:0009588 | non-traceable author statement <newline> phototransduction ; GO:0007602 | non-traceable author statement <newline> G-protein coupled receptor protein signaling pathway ; GO:0007186 | inferred from sequence or structural similarity <newline> absorption of visible light ; GO:0016038 | inferred from mutant phenotype <newline> visual perception ; GO:0007601 | inferred from electronic annotation with InterPro:IPR000856, InterPro:IPR001760 <newline> G-protein coupled receptor protein signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR000856, InterPro:IPR001760","integral to membrane ; GO:0016021 | inferred from sequence or structural similarity with Rh3 AND inferred from sequence or structural similarity with Rh4 AND inferred from sequence or structural similarity with ninaE <newline> integral to membrane ; GO:0016021 | inferred from sequence or structural similarity with EMBL:X80072; protein_id:CAA56378.1 AND inferred from sequence or structural similarity with Rh3 AND inferred from sequence or structural similarity with Rh4 <newline> rhabdomere ; GO:0016028 | inferred from direct assay <newline> integral to membrane ; GO:0016021 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | inferred from sequence or structural similarity","G-protein coupled photoreceptor activity ; GO:0008020 | inferred from genetic interaction with ninaE <newline> G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity with Rh3 AND inferred from sequence or structural similarity with Rh4 AND inferred from sequence or structural similarity with ninaE <newline> G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity with EMBL:X80072; protein_id:CAA56378.1 AND inferred from sequence or structural similarity with Rh3 AND inferred from sequence or structural similarity with Rh4 <newline> G-protein coupled photoreceptor activity ; GO:0008020 | non-traceable author statement <newline> G-protein coupled photoreceptor activity ; GO:0008020 | inferred from sequence or structural similarity"]
[null,"FBgn0040238","Bestrophin 1","Best1","The gene Bestrophin 1 is referred to in FlyBase by the symbol Dmel\\Best1 (CG6264, FBgn0040238). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5987186..5996207. It has the cytological map location 85F15-85F16. It is reported to have molecular function</span>: chloride channel activity. The biological processes in which it is involved are not known. 15 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","-","chloride channel activity ; GO:0005254 | non-traceable author statement"]

{"sheet":"Sheet4- Molecular Function","index":3,"n_rows":267,"n_cols":9,"rows_kept":267,"merged":[[1,2,1,4]],"flags":["formulas_cached_only"]}
[]
[null,null,"Classification based on developmental function"]
[]
["Category","Flybase ID","NAME","SYMBOL","Summary of gene function from Flybase","GO_BIOLOGICAL_PROCESS","GO_CELLULAR_COMPONENT","GO_MOLECULAR_FUNCTION"]
["Wing development"]
[null,"FBgn0000117","armadillo","arm","The gene armadillo is referred to in FlyBase by the symbol Dmel\\arm (CG11579, FBgn0000117). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1785434..1794673. It has the cytological map location 2B14. There is experimental evidence that it has the molecular function</span>: transcription activator activity; protein binding; transcription coactivator activity. There is experimental evidence for 22 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; cell adhesion; positive regulation of cellular biosynthetic process; regulation of developmental process; sensory organ development; positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; stem cell differentiation; reproductive process in a multicellular organism; delamination; cell junction organization. 177 alleles are reported. The phenotypes of these alleles are annotated with 100 unique terms, many of which group under: organ system; adult segment; abdominal ventral denticle belt; embryonic nervous system; female germline cyst; adult mesothoracic segment; embryonic/larval tracheal system; embryonic neuron; external compound sense organ; peripheral nervous system. It has 5 annotated transcripts and 5 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from sequence or structural similarity with MGD:Catnb; MGI:MGI:88276 <newline> cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | non-traceable author statement <newline> neuroblast fate determination ; GO:0007400 | non-traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> oocyte localization during germarium-derived egg chamber formation ; GO:0030720 | traceable author statement <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> heart development ; GO:0007507 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> positive regulation of JNK cascade ; GO:0046330 | traceable author statement <newline> protein localization ; GO:0008104 | traceable author statement <newline> germ-line stem cell division ; GO:0042078 | non-traceable author statement <newline> zonula adherens assembly ; GO:0045186 | traceable author statement <newline> establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement <newline> somatic stem cell maintenance ; GO:0035019 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype <newline> zonula adherens assembly ; GO:0045186 | inferred from mutant phenotype <newline> cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype <newline> cell morphogenesis ; GO:0000902 | inferred from mutant phenotype <newline> ventral furrow formation ; GO:0007370 | inferred from mutant phenotype <newline> neuroblast development ; GO:0014019 | inferred from mutant phenotype <newline> photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> compound eye retinal cell programmed cell death ; GO:0046667 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from direct assay <newline> imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype <newline> delamination ; GO:0060232 | inferred from mutant phenotype <newline> wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | inferred from mutant phenotype <newline> positive regulation of transcription ; GO:0045941 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | inferred from mutant phenotype","zonula adherens ; GO:0005915 | inferred from direct assay <newline> catenin complex ; GO:0016342 | inferred from sequence or structural similarity <newline> adherens junction ; GO:0005912 | non-traceable author statement <newline> catenin complex ; GO:0016342 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | non-traceable author statement <newline> membrane ; GO:0016020 | non-traceable author statement <newline> apicolateral plasma membrane ; GO:0016327 | traceable author statement <newline> adherens junction ; GO:0005912 | inferred from direct assay <newline> adherens junction ; GO:0005912 | traceable author statement <newline> cytoplasm ; GO:0005737 | traceable author statement <newline> spot adherens junction ; GO:0005914 | non-traceable author statement <newline> zonula adherens ; GO:0005915 | non-traceable author statement <newline> zonula adherens ; GO:0005915 | traceable author statement <newline> apical plasma membrane ; GO:0016324 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from physical interaction with pygo <newline> cytoplasm ; GO:0005737 | inferred from direct assay","cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity <newline> protein binding ; GO:0005515 | inferred from physical interaction with Apc2 AND inferred from physical interaction with Mer <newline> alpha-catenin binding ; GO:0045294 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P22265 <newline> transcription activator activity ; GO:0016563 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with Apc2 <newline> transcription coactivator activity ; GO:0003713 | inferred from direct assay"]
[null,"FBgn0000242","Beadex","Bx","The gene Beadex is referred to in FlyBase by the symbol Dmel\\Bx (CG6500, FBgn0000242). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:18428698..18465749. It has the cytological map location 17C3-17C4. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior; leg disc development; locomotor rhythm; imaginal disc-derived wing morphogenesis; leg segmentation; response to cocaine; phagocytosis, engulfment. 87 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: adult segment; adult mesothoracic segment; organ system; peripheral nervous system; thoracic segment; appendage segment; nervous system; wing hair; dorsal thoracic disc; unguis; metatarsus. It has 3 annotated transcripts and 3 annotated polypeptides.","imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from genetic interaction with ap AND inferred from mutant phenotype <newline> leg disc development ; GO:0035218 | inferred from mutant phenotype <newline> leg segmentation ; GO:0035286 | inferred from mutant phenotype <newline> locomotor rhythm ; GO:0045475 | inferred from mutant phenotype <newline> response to cocaine ; GO:0042220 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype","nucleus ; GO:0005634 | non-traceable author statement","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781"]
[null,"FBgn0000308","chickadee","chic","The gene chickadee is referred to in FlyBase by the symbol Dmel\\chic (CG9553, FBgn0000308). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:5972900..5981025. It has the cytological map location 26A5-26B2. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; central nervous system development; multicellular organism reproduction; organelle organization; organ development; post-embryonic morphogenesis; cell morphogenesis; gamete generation; cell division; actin filament-based process; ovarian nurse cell to oocyte transport; cellular localization. 65 alleles are reported. The phenotypes of these alleles are annotated with 32 unique terms, many of which group under: organ system; female germline cyst; peripheral nervous system; adult segment; nervous system; multi-cell-component structure; egg; spermatocyte; male germline cyst; embryonic nervous system; adult mesothoracic segment; portion of tissue. It has 4 annotated transcripts and 4 annotated polypeptides.","ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype <newline> spermatogenesis ; GO:0007283 | inferred from mutant phenotype <newline> brain development ; GO:0007420 | inferred from genetic interaction with cib <newline> larval central nervous system remodeling ; GO:0035193 | inferred from genetic interaction with cib <newline> cytokinesis, actomyosin contractile ring assembly ; GO:0000915 | traceable author statement <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype <newline> cell morphogenesis ; GO:0000902 | inferred from mutant phenotype <newline> cytokinesis ; GO:0000910 | inferred from mutant phenotype <newline> brain development ; GO:0007420 | inferred from mutant phenotype <newline> actin polymerization or depolymerization ; GO:0008154 | non-traceable author statement <newline> actin filament organization ; GO:0007015 | traceable author statement <newline> pole plasm oskar mRNA localization ; GO:0045451 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> actin filament polymerization ; GO:0030041 | traceable author statement <newline> karyosome formation ; GO:0030717 | inferred from mutant phenotype <newline> histoblast morphogenesis ; GO:0007488 | inferred from mutant phenotype <newline> maintenance of protein location in cell ; GO:0032507 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype","actin cytoskeleton ; GO:0015629 | inferred from electronic annotation with InterPro:IPR002097","actin binding ; GO:0003779 | inferred from sequence or structural similarity <newline> actin binding ; GO:0003779 | non-traceable author statement <newline> phosphatidylinositol-4,5-bisphosphate binding ; GO:0005546 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q8T4F7 <newline> protein binding ; GO:0005515 | inferred from physical interaction with dia <newline> actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR002097, InterPro:IPR005455"]
[null,"FBgn0000497","dachsous","ds","The gene dachsous is referred to in FlyBase by the symbol Dmel\\ds (CG17941, FBgn0000497). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:640021..714968. It has the cytological map location 21E2. There is experimental evidence that it has the molecular function</span>: cell adhesion molecule binding. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; establishment of planar polarity; sensory organ development; organ development; cell morphogenesis; epithelial cell differentiation; cell proliferation; biopolymer modification; cell adhesion. 60 alleles are reported. The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; thoracic segment; peripheral nervous system; external compound sense organ; nervous system; appendage segment; wing hair; dorsal thoracic disc; adult cuticle. It has one annotated transcript and one annotated polypeptide.","establishment of planar polarity ; GO:0001736 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from mutant phenotype <newline> cell morphogenesis involved in differentiation ; GO:0000904 | inferred from mutant phenotype <newline> peptide cross-linking ; GO:0018149 | inferred from physical interaction with ft <newline> calcium-dependent cell-cell adhesion ; GO:0016339 | inferred from sequence or structural similarity <newline> establishment of ommatidial planar polarity ; GO:0042067 | inferred from mutant phenotype <newline> equator specification ; GO:0045317 | inferred from mutant phenotype <newline> establishment of epithelial cell apical/basal polarity ; GO:0045198 | inferred from mutant phenotype <newline> wing disc pattern formation ; GO:0035222 | inferred from mutant phenotype <newline> establishment of cell polarity ; GO:0030010 | inferred from mutant phenotype <newline> eye morphogenesis ; GO:0048592 | inferred from mutant phenotype <newline> imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> homophilic cell adhesion ; GO:0007156 | inferred from sequence or structural similarity <newline> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | traceable author statement <newline> ommatidial rotation ; GO:0016318 | traceable author statement <newline> establishment of tissue polarity ; GO:0007164 | non-traceable author statement <newline> establishment of planar polarity ; GO:0001736 | traceable author statement <newline> establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement <newline> calcium-dependent cell-cell adhesion ; GO:0016339 | inferred from sequence or structural similarity with UniProtKB:P33450 <newline> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | inferred from mutant phenotype <newline> cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype <newline> homophilic cell adhesion ; GO:0007156 | inferred from electronic annotation with InterPro:IPR000233, InterPro:IPR002126","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> integral to plasma membrane ; GO:0005887 | inferred from sequence or structural similarity <newline> integral to membrane ; GO:0016021 | traceable author statement <newline> integral to plasma membrane ; GO:0005887 | inferred from sequence or structural similarity with UniProtKB:P33450","cell adhesion molecule binding ; GO:0050839 | inferred from direct assay <newline> cell adhesion molecule binding ; GO:0050839 | inferred from sequence or structural similarity <newline> receptor activity ; GO:0004872 | inferred from sequence or structural similarity <newline> signal transducer activity ; GO:0004871 | non-traceable author statement <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR000233, InterPro:IPR002126, InterPro:IPR015919"]
[null,"FBgn0000658","four-jointed","fj","The gene four-jointed is referred to in FlyBase by the symbol Dmel\\fj (CG10917, FBgn0000658). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14120268..14123816. It has the cytological map location 55C1. There is experimental evidence that it has the molecular function</span>: protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: cell-cell signaling; imaginal disc-derived wing vein specification; establishment of epithelial cell apical/basal polarity; imaginal disc growth; imaginal disc-derived leg joint morphogenesis. 46 alleles are reported. The phenotypes of these alleles are annotated with 27 unique terms, many of which group under: adult segment; adult mesothoracic segment; appendage segment; organ system; thoracic segment; external compound sense organ; peripheral nervous system; metatarsus; antennal segment; nervous system. It has one annotated transcript and one annotated polypeptide.","cell-cell signaling ; GO:0007267 | inferred from direct assay AND inferred from sequence or structural similarity <newline> imaginal disc growth ; GO:0007446 | inferred from mutant phenotype <newline> cell-cell signaling ; GO:0007267 | inferred from expression pattern AND inferred from mutant phenotype <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype <newline> imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype <newline> establishment of epithelial cell apical/basal polarity ; GO:0045198 | inferred from mutant phenotype <newline> establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement <newline> establishment of planar polarity ; GO:0001736 | traceable author statement <newline> cell-cell signaling ; GO:0007267 | non-traceable author statement <newline> imaginal disc development ; GO:0007444 | non-traceable author statement <newline> proximal/distal pattern formation, imaginal disc ; GO:0007449 | non-traceable author statement","plasma membrane ; GO:0005886 | inferred from direct assay AND inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | non-traceable author statement","protein kinase activity ; GO:0004672 | inferred from direct assay"]
[null,"FBgn0001235","homothorax","hth","The gene homothorax is referred to in FlyBase by the symbol Dmel\\hth (CG17117, FBgn0001235). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:6335569..6464386. It has the cytological map location 86C1-86C3. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of gene-specific transcription from RNA polymerase II promoter; compound eye development; specification of segmental identity, antennal segment; specification of segmental identity, head; segmentation; compound eye photoreceptor fate commitment; brain development; imaginal disc-derived wing morphogenesis; haltere morphogenesis; imaginal disc-derived leg morphogenesis. 64 alleles are reported. The phenotypes of these alleles are annotated with 63 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; thoracic segment; external compound sense organ; appendage segment; adult mesothoracic segment; embryonic segment; embryonic nervous system; organ system; antennal segment. It has 8 annotated transcripts and 8 annotated polypeptides.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> brain development ; GO:0007420 | inferred from mutant phenotype <newline> proximal/distal pattern formation ; GO:0009954 | traceable author statement <newline> specification of organ identity ; GO:0010092 | traceable author statement <newline> compound eye photoreceptor fate commitment ; GO:0001752 | inferred from mutant phenotype <newline> leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype <newline> specification of segmental identity, antennal segment ; GO:0007383 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype <newline> haltere morphogenesis ; GO:0048735 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> transcription factor activity ; GO:0003700 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356"]
[null,"FBgn0001269","invected","inv","The gene invected is referred to in FlyBase by the symbol Dmel\\inv (CG17835, FBgn0001269). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7361970..7394688. It has the cytological map location 47F15-47F17. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: neuroblast fate determination; compartment specification. 37 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; thoracic segment; adult; cuticle; multi-cell-component structure; embryonic hindgut; embryonic nervous system; nervous system; region of integument; developing anatomical structure. It has 4 annotated transcripts and 4 annotated polypeptides.","compartment pattern formation ; GO:0007386 | inferred from mutant phenotype AND inferred from sequence or structural similarity with en <newline> neuroblast fate determination ; GO:0007400 | inferred from genetic interaction with en, gsb AND inferred from genetic interaction with en, gsb, ptc <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with EMBL:AF213356 <newline> compartment pattern formation ; GO:0007386 | traceable author statement <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | traceable author statement","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q05925 <newline> nucleus ; GO:0005634 | non-traceable author statement","RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity with EMBL:AF213356 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000047, InterPro:IPR001356"]
[null,"FBgn0002643","mastermind","mam","The gene mastermind is referred to in FlyBase by the symbol Dmel\\mam (CG8118, FBgn0002643). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9878686..9947861. It has the cytological map location 50C23-50D3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: transcription coactivator activity. There is experimental evidence that it is involved in the biological process</span>: germ-line stem cell maintenance; heart morphogenesis; apposition of dorsal and ventral imaginal disc-derived wing surfaces; mesodermal cell fate determination; imaginal disc-derived wing margin morphogenesis; somatic stem cell maintenance; bristle morphogenesis; imaginal disc-derived wing morphogenesis; asymmetric cell division. 194 alleles are reported. The phenotypes of these alleles are annotated with 73 unique terms, many of which group under: synaptic neuropil subdomain; adult segment; antennal segment; embryonic nervous system; adult mesothoracic segment; embryonic neuron; peripheral nervous system; embryonic glial cell; germarium; external compound sense organ. It has 3 annotated transcripts and 3 annotated polypeptides.","ectoderm development ; GO:0007398 | traceable author statement <newline> mesodermal cell fate determination ; GO:0007500 | inferred from mutant phenotype <newline> apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> asymmetric cell division ; GO:0008356 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | traceable author statement <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> heart morphogenesis ; GO:0003007 | inferred from mutant phenotype <newline> somatic stem cell maintenance ; GO:0035019 | inferred from mutant phenotype <newline> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from electronic annotation with InterPro:IPR019082 <newline> Notch signaling pathway ; GO:0007219 | inferred from electronic annotation with InterPro:IPR019082","nucleus ; GO:0005634 | inferred from direct assay AND inferred from sequence or structural similarity <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nuclear speck ; GO:0016607 | inferred from electronic annotation with InterPro:IPR019082","transcription coactivator activity ; GO:0003713 | inferred from electronic annotation with InterPro:IPR019082"]
[null,"FBgn0002733","E(spl) region transcript mbeta","HLHmbeta","The gene E(spl) region transcript m? is referred to in FlyBase by the symbol Dmel\\HLHm? (CG14548, FBgn0002733). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21830648..21831745. It has the cytological map location 96F9. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: negative regulation of transcription from RNA polymerase II promoter. 7 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; wing margin bristle; macrochaeta; anterior crossvein; scutellar bristle; microchaeta; wing vein. It has one annotated transcript and one annotated polypeptide.","negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> negative regulation of transcription ; GO:0016481 | non-traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> compound eye development ; GO:0048749 | traceable author statement","nucleus ; GO:0005634 | inferred by curator from GO:0003677 <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR011598","transcription factor activity ; GO:0003700 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> transcription repressor activity ; GO:0016564 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from direct assay"]
[null,"FBgn0002735","E(spl) region transcript mgamma","HLHmgamma","The gene E(spl) region transcript m? is referred to in FlyBase by the symbol Dmel\\HLHm? (CG8333, FBgn0002735). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21825580..21826421. It has the cytological map location 96F9. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding; transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of transcription; wing disc dorsal/ventral pattern formation. 10 alleles are reported. The phenotypes of these alleles are annotated with: adult thorax; wing margin bristle; macrochaeta; scutellar bristle; microchaeta; wing vein. It has one annotated transcript and one annotated polypeptide.","negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> negative regulation of transcription ; GO:0016481 | non-traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> compound eye development ; GO:0048749 | traceable author statement <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> negative regulation of transcription ; GO:0016481 | inferred from direct assay","nucleus ; GO:0005634 | inferred by curator from GO:0003677 <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR011598","transcription factor activity ; GO:0003700 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> transcription repressor activity ; GO:0016564 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | inferred from direct assay <newline> sequence-specific DNA binding ; GO:0043565 | inferred from direct assay"]
[null,"FBgn0003016","outspread","osp","The gene outspread is referred to in FlyBase by the symbol Dmel\\osp (CG3479, FBgn0003016). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:14599776..14689325. It has the cytological map location 35B3-35B4. Its molecular function is unknown. The biological processes in which it is involved are not known. 53 alleles are reported. The phenotypes of these alleles are annotated with: wing; thorax; crystal cell. It has 4 annotated transcripts and 4 annotated polypeptides.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
[null,"FBgn0003310","Star","S","The gene Star is referred to in FlyBase by the symbol Dmel\\S (CG4385, FBgn0003310). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:1050877..1077811. It has the cytological map location 21E4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: epidermal growth factor ligand processing; stomatogastric nervous system development; determination of genital disc primordium; protein targeting to Golgi; compound eye retinal cell programmed cell death; regulation of epidermal growth factor receptor signaling pathway; ommatidial rotation; imaginal disc-derived wing morphogenesis; behavioral response to ethanol. 151 alleles are reported. The phenotypes of these alleles are annotated with 58 unique terms, many of which group under: organ system; embryonic nervous system; peripheral nervous system; nervous system; adult segment; external compound sense organ; adult mesothoracic segment; embryonic neuron; multi-cell-component structure; female germline cyst; commissure. It has 2 annotated transcripts and 2 annotated polypeptides.","epidermal growth factor ligand processing ; GO:0007174 | inferred from genetic interaction with spi <newline> protein targeting to Golgi ; GO:0000042 | inferred from genetic interaction with spi <newline> regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from genetic interaction with rho, spi <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | traceable author statement <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | non-traceable author statement <newline> compound eye photoreceptor development ; GO:0042051 | non-traceable author statement <newline> protein targeting to Golgi ; GO:0000042 | non-traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> embryonic development ; GO:0009790 | traceable author statement <newline> mesoderm development ; GO:0007498 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> photoreceptor cell development ; GO:0042461 | traceable author statement <newline> regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | traceable author statement <newline> protein targeting to Golgi ; GO:0000042 | traceable author statement <newline> determination of genital disc primordium ; GO:0035225 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | traceable author statement <newline> behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype <newline> stomatogastric nervous system development ; GO:0007421 | inferred from mutant phenotype <newline> compound eye retinal cell programmed cell death ; GO:0046667 | inferred from mutant phenotype <newline> ommatidial rotation ; GO:0016318 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> membrane ; GO:0016020 | non-traceable author statement <newline> Golgi apparatus ; GO:0005794 | non-traceable author statement <newline> endoplasmic reticulum ; GO:0005783 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | traceable author statement","-"]
[null,"FBgn0003326","scabrous","sca","The gene scabrous is referred to in FlyBase by the symbol Dmel\\sca (CG17579, FBgn0003326). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8668049..8689515. It has the cytological map location 49C3-49D3. It is reported to have molecular function</span>: signal transducer activity. There is experimental evidence that it is involved in the biological process</span>: female meiosis chromosome segregation; compound eye development; imaginal disc-derived wing margin morphogenesis; nervous system development; ommatidial rotation; bristle morphogenesis. 71 alleles are reported. The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: peripheral nervous system; nervous system; adult segment; external compound sense organ; organ system; adult mesothoracic segment; plasma membrane part; plasma membrane; eo support cell; acrostichal bristle; imaginal precursor; adult cuticle; antennal segment. It has 2 annotated transcripts and 2 annotated polypeptides.","bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | inferred from genetic interaction with N <newline> female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype <newline> ommatidial rotation ; GO:0016318 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> lateral inhibition ; GO:0046331 | non-traceable author statement <newline> regulation of R8 cell spacing in compound eye ; GO:0045468 | traceable author statement <newline> regulation of R8 cell spacing in compound eye ; GO:0045468 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from genetic interaction with hh AND inferred from mutant phenotype <newline> R8 cell fate commitment ; GO:0007460 | traceable author statement <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002181, InterPro:IPR014716","fibrinogen complex ; GO:0005577 | inferred from sequence or structural similarity with NCBI_gi:4758348 <newline> extracellular region ; GO:0005576 | non-traceable author statement","signal transducer activity ; GO:0004871 | traceable author statement <newline> receptor binding ; GO:0005102 | inferred from electronic annotation with InterPro:IPR002181, InterPro:IPR014716"]
[null,"FBgn0003371","shaggy","sgg","The gene shaggy is referred to in FlyBase by the symbol Dmel\\sgg (CG2621, FBgn0003371). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2527983..2571879. It has the cytological map location 3A8-3B1. There is experimental evidence that it has the molecular function</span>: protein kinase activity; kinase activity. There is experimental evidence for 16 unique biological process</span> terms, many of which group under: anatomical structure development; regulation of biological process; reproductive process in a multicellular organism; organ development; learning; regulation of circadian rhythm; multicellular organism reproduction; learning or memory; regionalization; biopolymer modification; circadian rhythm; regulation of developmental process; embryonic pattern specification; olfactory learning; entrainment of circadian clock; regulation of metabolic process. 149 alleles are reported. The phenotypes of these alleles are annotated with 44 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; abdominal ventral denticle belt; nervous system; external compound sense organ; cuticle; larval abdominal segment; embryonic/larval hemocoel. It has 15 annotated transcripts and 15 annotated polypeptides.","synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> circadian rhythm ; GO:0007623 | inferred from mutant phenotype <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype <newline> heart development ; GO:0007507 | non-traceable author statement <newline> protein localization ; GO:0008104 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> negative regulation of Wnt receptor signaling pathway ; GO:0030178 | traceable author statement <newline> blastoderm segmentation ; GO:0007350 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> bristle morphogenesis ; GO:0008407 | non-traceable author statement <newline> circadian rhythm ; GO:0007623 | non-traceable author statement <newline> locomotor rhythm ; GO:0045475 | non-traceable author statement <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from direct assay <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay <newline> regulation of proteolysis ; GO:0030162 | inferred from direct assay <newline> circadian rhythm ; GO:0007623 | traceable author statement <newline> Notch signaling pathway ; GO:0007219 | traceable author statement <newline> regulation of protein import into nucleus ; GO:0042306 | traceable author statement <newline> rhythmic behavior ; GO:0007622 | traceable author statement <newline> regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype <newline> entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype <newline> wing and notum subfield formation ; GO:0035309 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> olfactory learning ; GO:0008355 | inferred from mutant phenotype <newline> habituation ; GO:0046959 | inferred from mutant phenotype <newline> regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype","-","protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity <newline> protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement <newline> kinase activity ; GO:0016301 | inferred from direct assay <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> glycogen synthase kinase 3 activity ; GO:0004696 | non-traceable author statement <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017442 <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR002290, InterPro:IPR008271"]
[null,"FBgn0003396","schnurri","shn","The gene schnurri is referred to in FlyBase by the symbol Dmel\\shn (CG7734, FBgn0003396). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7061325..7104918. It has the cytological map location 47D6-47D7. There is experimental evidence that it has the molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: olfactory learning; ectoderm development; learning or memory; cell proliferation; imaginal disc-derived wing vein morphogenesis; wing disc anterior/posterior pattern formation; wing disc dorsal/ventral pattern formation; imaginal disc-derived wing morphogenesis; midgut development. 108 alleles are reported. The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; peripheral nervous system; adult segment; embryonic nervous system; adult mesothoracic segment; nervous system; external compound sense organ; primordium; embryonic peripheral nervous system; embryonic head; midgut constriction; podocyte; organ system subdivision; multi-cell-component structure; spiracle. It has 4 annotated transcripts and 4 annotated polypeptides.","ectoderm development ; GO:0007398 | inferred from mutant phenotype <newline> midgut development ; GO:0007494 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from mutant phenotype <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from genetic interaction with dpp AND inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> learning or memory ; GO:0007611 | inferred from mutant phenotype <newline> olfactory learning ; GO:0008355 | inferred from mutant phenotype <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement <newline> negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement <newline> compound eye morphogenesis ; GO:0001745 | non-traceable author statement <newline> negative regulation of cell proliferation ; GO:0008285 | non-traceable author statement <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap","nucleus ; GO:0005634 | non-traceable author statement <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:X51435; protein_id:CAA35798.1 <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from mutant phenotype <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003604, InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0003415","skuld","skd","The gene skuld is referred to in FlyBase by the symbol Dmel\\skd (CG9936, FBgn0003415). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20987228..21020524. It has the cytological map location 78A2. There is experimental evidence that it has the molecular function</span>: protein binding; RNA polymerase II transcription mediator activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of Wnt receptor signaling pathway; sex comb development; wing disc dorsal/ventral pattern formation; regulation of transcription from RNA polymerase II promoter; embryonic development; cell fate commitment. 44 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; eye disc; mitotic cell cycle; antennal disc; photoreceptor cell; crystal cell; larval mouth. It has 3 annotated transcripts and 3 annotated polypeptides.","cell fate commitment ; GO:0045165 | inferred from genetic interaction with Scr <newline> embryonic development ; GO:0009790 | inferred from mutant phenotype <newline> sex comb development ; GO:0045498 | inferred from genetic interaction with Scr AND inferred from mutant phenotype <newline> transcription initiation from RNA polymerase II promoter ; GO:0006367 | inferred from sequence or structural similarity with HGNC_gene:THRAP1; HGNC:22474; OMIM:603808 <newline> transcription from RNA polymerase II promoter ; GO:0006366 | non-traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from direct assay <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> positive regulation of Wnt receptor signaling pathway ; GO:0030177 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay <newline> mediator complex ; GO:0016592 | inferred from sequence or structural similarity with HGNC_gene:THRAP1; HGNC:22474; OMIM:603808 <newline> mediator complex ; GO:0016592 | non-traceable author statement <newline> mediator complex ; GO:0016592 | inferred from direct assay","RNA polymerase II transcription mediator activity ; GO:0016455 | inferred from sequence or structural similarity with HGNC_gene:THRAP1; HGNC:22474; OMIM:603808 <newline> RNA polymerase II transcription mediator activity ; GO:0016455 | non-traceable author statement <newline> serine-type endopeptidase activity ; GO:0004252 | NOT non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VW47 <newline> RNA polymerase II transcription mediator activity ; GO:0016455 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VT57"]
[null,"FBgn0003463","short gastrulation","sog","The gene short gastrulation is referred to in FlyBase by the symbol Dmel\\sog (CG9224, FBgn0003463). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15498603..15520573. It has the cytological map location 13E1. It is reported to have molecular function</span>: growth factor activity. There is experimental evidence that it is involved in the biological process</span>: torso signaling pathway; terminal region determination; ring gland development; imaginal disc-derived wing vein morphogenesis; maternal specification of dorsal/ventral axis, oocyte, soma encoded. 104 alleles are reported. The phenotypes of these alleles are annotated with 33 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; embryonic nervous system; peripheral nervous system; primordium; embryonic/larval tracheal system; thoracic segment; embryonic peripheral nervous system; extended germ band embryo. It has one annotated transcript and one annotated polypeptide.","amnioserosa formation ; GO:0007378 | traceable author statement <newline> terminal region determination ; GO:0007362 | inferred from genetic interaction with tor <newline> torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor <newline> ring gland development ; GO:0035271 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> ectoderm development ; GO:0007398 | non-traceable author statement <newline> negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | non-traceable author statement <newline> BMP signaling pathway ; GO:0030509 | non-traceable author statement <newline> zygotic determination of anterior/posterior axis, embryo ; GO:0007354 | non-traceable author statement <newline> regulation of BMP signaling pathway ; GO:0030510 | traceable author statement <newline> ectoderm development ; GO:0007398 | traceable author statement <newline> negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | traceable author statement <newline> positive regulation of transforming growth factor beta receptor signaling pathway ; GO:0030511 | traceable author statement <newline> maternal specification of dorsal/ventral axis, oocyte, soma encoded ; GO:0007313 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | non-traceable author statement","growth factor activity ; GO:0008083 | non-traceable author statement"]
[null,"FBgn0003716","thickveins","tkv","The gene thickveins is referred to in FlyBase by the symbol Dmel\\tkv (CG14026, FBgn0003716). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:5218996..5271353. It has the cytological map location 25D1-25D2. There is experimental evidence that it has the molecular function</span>: transforming growth factor beta receptor activity, type I; specific transcriptional repressor activity; transforming growth factor beta binding. There is experimental evidence for 19 unique biological process</span> terms, many of which group under: anatomical structure development; regulation of biological process; regulation of developmental process; organ development; organ morphogenesis; reproductive process in a multicellular organism; synaptic transmission; regionalization; positive regulation of developmental process; enzyme linked receptor protein signaling pathway. 103 alleles are reported. The phenotypes of these alleles are annotated with 87 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; embryonic/larval tracheal system; primordium; peripheral nervous system; germarium; embryonic nervous system; egg; external compound sense organ; late extended germ band embryo. It has 4 annotated transcripts and 4 annotated polypeptides.","neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype <newline> decapentaplegic receptor signaling pathway ; GO:0008101 | inferred from mutant phenotype inferred from genetic interaction with dpp <newline> dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype inferred from genetic interaction with dpp <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | inferred from genetic interaction with dpp AND inferred from physical interaction with dpp <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from genetic interaction with dpp AND inferred from mutant phenotype <newline> anterior/posterior pattern formation, imaginal disc ; GO:0007448 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | inferred from mutant phenotype <newline> BMP signaling pathway ; GO:0030509 | traceable author statement <newline> germ-line stem cell division ; GO:0042078 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | non-traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> morphogenesis of a branching structure ; GO:0001763 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | non-traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> transforming growth factor beta receptor complex assembly ; GO:0007181 | non-traceable author statement <newline> negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement <newline> compound eye morphogenesis ; GO:0001745 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> genital disc development ; GO:0035215 | inferred from mutant phenotype <newline> regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype <newline> chorion-containing eggshell formation ; GO:0007304 | inferred from genetic interaction with sax <newline> positive regulation of muscle organ development ; GO:0048636 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> regulation of cell-cell adhesion ; GO:0022407 | inferred from mutant phenotype <newline> regulation of cell differentiation ; GO:0045595 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR003605, InterPro:IPR008271, InterPro:IPR017441, InterPro:IPR017442","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with babo <newline> plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> multivesicular body ; GO:0005771 | inferred from direct assay","transforming growth factor beta binding ; GO:0050431 | inferred from physical interaction with dpp <newline> transforming growth factor beta receptor activity, type I ; GO:0005025 | inferred from physical interaction with dpp <newline> transforming growth factor beta receptor activity, type I ; GO:0005025 | inferred from sequence or structural similarity <newline> transforming growth factor beta receptor activity, type I ; GO:0005025 | non-traceable author statement <newline> protein kinase activity ; GO:0004672 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR003605, InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0004101","blistered","bs","The gene blistered is referred to in FlyBase by the symbol Dmel\\bs (CG3411, FBgn0004101). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20231236..20263998. It has the cytological map location 60C6-60C7. It is reported to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: apposition of dorsal and ventral imaginal disc-derived wing surfaces; terminal branching, open tracheal system; imaginal disc-derived wing morphogenesis; sleep; open tracheal system development. 61 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; thoracic segment; tracheal system; embryonic/larval tracheal system; appendage segment; cuticle; wing cell; embryonic tracheal system; organ system subdivision; cephalopharyngeal skeleton; peripheral nervous system. It has 2 annotated transcripts and 2 annotated polypeptides.","open tracheal system development ; GO:0007424 | inferred from expression pattern <newline> terminal branching, open tracheal system ; GO:0007430 | inferred from mutant phenotype <newline> terminal branching, open tracheal system ; GO:0007430 | traceable author statement <newline> apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype <newline> cell fate commitment ; GO:0045165 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> terminal cell fate specification, open tracheal system ; GO:0035154 | traceable author statement <newline> open tracheal system development ; GO:0007424 | non-traceable author statement <newline> terminal branching, open tracheal system ; GO:0007430 | non-traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> sleep ; GO:0030431 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR002100","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR002100 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR002100"]
[null,"FBgn0004399","pipsqueak","psq","The gene pipsqueak is referred to in FlyBase by the symbol Dmel\\psq (CG2368, FBgn0004399). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6445409..6503753. It has the cytological map location 47A13-47B1. It is reported to have molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: olfactory behavior; imaginal disc-derived wing morphogenesis. 79 alleles are reported. The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: embryonic abdomen; embryonic segment; organ system; embryonic tagma; peripheral nervous system; female germline cyst; external compound sense organ; adult segment; nervous system; adult mesothoracic segment. It has 12 annotated transcripts and 12 annotated polypeptides.","pole plasm assembly ; GO:0007315 | non-traceable author statement <newline> gene silencing ; GO:0016458 | traceable author statement <newline> olfactory behavior ; GO:0042048 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype","nucleus ; GO:0005634 | traceable author statement","DNA binding ; GO:0003677 | non-traceable author statement <newline> DNA binding ; GO:0003677 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR011526 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000210, InterPro:IPR011333, InterPro:IPR013069"]
[null,"FBgn0004644","hedgehog","hh","The gene hedgehog is referred to in FlyBase by the symbol Dmel\\hh (CG4637, FBgn0004644). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:18953425..18967881. It has the cytological map location 94E1. There is experimental evidence that it has the molecular function</span>: cell surface binding; protein binding. There is experimental evidence for 24 unique biological process</span> terms, many of which group under: anatomical structure development; cellular component movement; organ morphogenesis; regulation of biological process; sensory organ development; reproductive process in a multicellular organism; organ development; regulation of protein transport; cell projection organization; open tracheal system development; central nervous system development. 170 alleles are reported. The phenotypes of these alleles are annotated with 190 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; primordium; nervous system; late extended germ band embryo; ventral nerve cord primordium; embryonic nervous system; abdominal ventral denticle belt. It has 2 annotated transcripts and 2 annotated polypeptides.","pole cell migration ; GO:0007280 | inferred from genetic interaction with Hmgcr inferred from genetic interaction with disp <newline> progression of morphogenetic furrow during compound eye morphogenesis ; GO:0007458 | inferred from expression pattern AND inferred from genetic interaction with dpp AND inferred from genetic interaction with h AND inferred from genetic interaction with sca AND inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo <newline> germ cell migration ; GO:0008354 | inferred from mutant phenotype <newline> gonadal mesoderm development ; GO:0007506 | inferred from mutant phenotype <newline> positive regulation of hh target transcription factor activity ; GO:0007228 | inferred from genetic interaction with Su(fu) AND inferred from genetic interaction with fu <newline> Bolwig's organ morphogenesis ; GO:0001746 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | traceable author statement <newline> hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype <newline> regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype <newline> epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype <newline> glial cell migration ; GO:0008347 | inferred from mutant phenotype <newline> labial disc development ; GO:0035217 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> morphogenesis of larval imaginal disc epithelium ; GO:0016335 | inferred from mutant phenotype <newline> protein autoprocessing ; GO:0016540 | inferred from direct assay AND inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | traceable author statement <newline> positive regulation of smoothened signaling pathway ; GO:0045880 | traceable author statement <newline> protein autoprocessing ; GO:0016540 | traceable author statement <newline> protein splicing ; GO:0030908 | traceable author statement <newline> cytoneme assembly ; GO:0035231 | inferred from mutant phenotype <newline> foregut morphogenesis ; GO:0007440 | traceable author statement <newline> hindgut morphogenesis ; GO:0007442 | traceable author statement <newline> anterior/posterior lineage restriction, imaginal disc ; GO:0048099 | traceable author statement <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | traceable author statement <newline> imaginal disc-derived wing vein specification ; GO:0007474 | traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> ovarian follicle cell stalk formation ; GO:0030713 | traceable author statement <newline> epidermis development ; GO:0008544 | traceable author statement <newline> growth ; GO:0040007 | non-traceable author statement <newline> germ-line stem cell division ; GO:0042078 | traceable author statement <newline> ectoderm development ; GO:0007398 | non-traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> mesoderm development ; GO:0007498 | non-traceable author statement <newline> imaginal disc pattern formation ; GO:0007447 | non-traceable author statement <newline> regulation of organ growth ; GO:0046620 | traceable author statement <newline> analia development ; GO:0007487 | traceable author statement <newline> genital disc development ; GO:0035215 | traceable author statement <newline> leg disc morphogenesis ; GO:0007478 | traceable author statement <newline> regulation of cell proliferation ; GO:0042127 | non-traceable author statement <newline> compartment pattern formation ; GO:0007386 | traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | non-traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | traceable author statement <newline> segment polarity determination ; GO:0007367 | non-traceable author statement <newline> anterior/posterior axis specification, embryo ; GO:0008595 | non-traceable author statement <newline> R8 cell fate specification ; GO:0045464 | non-traceable author statement <newline> heart development ; GO:0007507 | non-traceable author statement <newline> progression of morphogenetic furrow during compound eye morphogenesis ; GO:0007458 | traceable author statement <newline> somatic stem cell division ; GO:0048103 | traceable author statement <newline> protein autoprocessing ; GO:0016540 | non-traceable author statement <newline> wing disc proximal/distal pattern formation ; GO:0007473 | traceable author statement <newline> germ cell attraction ; GO:0035232 | traceable author statement <newline> developmental pigmentation ; GO:0048066 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> regulation of protein import into nucleus ; GO:0042306 | inferred from mutant phenotype <newline> imaginal disc growth ; GO:0007446 | traceable author statement <newline> anterior head segmentation ; GO:0035288 | traceable author statement <newline> posterior head segmentation ; GO:0035289 | traceable author statement <newline> segment polarity determination ; GO:0007367 | traceable author statement <newline> trunk segmentation ; GO:0035290 | traceable author statement <newline> genital disc development ; GO:0035215 | inferred from mutant phenotype <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | traceable author statement <newline> genital disc anterior/posterior pattern formation ; GO:0035224 | inferred from expression pattern <newline> eye morphogenesis ; GO:0048592 | inferred from mutant phenotype <newline> ventral midline development ; GO:0007418 | inferred from mutant phenotype <newline> anterior commissure morphogenesis ; GO:0021960 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from expression pattern <newline> positive regulation of transcription factor import into nucleus ; GO:0042993 | inferred from mutant phenotype <newline> cell-cell signaling ; GO:0007267 | inferred from electronic annotation with InterPro:IPR000320 <newline> proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001767 <newline> intein-mediated protein splicing ; GO:0016539 | inferred from electronic annotation with InterPro:IPR006141","extracellular region ; GO:0005576 | traceable author statement <newline> cytoplasmic membrane-bounded vesicle ; GO:0016023 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | non-traceable author statement <newline> extracellular region ; GO:0005576 | non-traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> endocytic vesicle ; GO:0030139 | inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with iHog <newline> cell surface binding ; GO:0043498 | inferred from direct assay <newline> patched binding ; GO:0005113 | traceable author statement <newline> cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity <newline> signal transducer activity ; GO:0004871 | traceable author statement <newline> morphogen activity ; GO:0016015 | traceable author statement <newline> endopeptidase activity ; GO:0004175 | non-traceable author statement <newline> patched binding ; GO:0005113 | non-traceable author statement <newline> peptidase activity ; GO:0008233 | inferred from electronic annotation with InterPro:IPR001767"]
[null,"FBgn0004647","Notch","N","The gene Notch is referred to in FlyBase by the symbol Dmel\\N (CG3936, FBgn0004647). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3028905..3066295. It has the cytological map location 3C7-3C9. There is experimental evidence that it has the molecular function</span>: protein binding; specific transcriptional repressor activity; transcription activator activity. There is experimental evidence for 54 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; organ development; regulation of developmental process; sensory organ development; organ morphogenesis; regulation of neurogenesis; cellular component movement; ovarian follicle cell development; regulation of biological process. 653 alleles are reported. The phenotypes of these alleles are annotated with 219 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; adult mesothoracic segment; organ system; external compound sense organ; embryonic nervous system; multi-cell-component structure; primordium; embryonic neuron. It has one annotated transcript and one annotated polypeptide.","stem cell differentiation ; GO:0048863 | inferred from mutant phenotype <newline> regulation of neurogenesis ; GO:0050767 | inferred from mutant phenotype <newline> ectoderm development ; GO:0007398 | traceable author statement <newline> mesoderm development ; GO:0007498 | inferred from mutant phenotype <newline> ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> leg joint morphogenesis ; GO:0035111 | inferred from mutant phenotype <newline> leg segmentation ; GO:0035286 | inferred from mutant phenotype <newline> R8 cell development ; GO:0045463 | traceable author statement <newline> cell adhesion ; GO:0007155 | traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> glial cell fate determination ; GO:0007403 | inferred from mutant phenotype <newline> peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype <newline> germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> muscle cell fate determination ; GO:0007521 | inferred from mutant phenotype <newline> regulation of cardioblast cell fate specification ; GO:0042686 | inferred from mutant phenotype <newline> regulation of growth ; GO:0040008 | inferred from genetic interaction with scrib AND inferred from mutant phenotype <newline> foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype <newline> oocyte localization during germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> anesthesia-resistant memory ; GO:0007615 | NOT inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from mutant phenotype <newline> lateral inhibition ; GO:0046331 | traceable author statement <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype <newline> cell fate specification ; GO:0001708 | traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> anterior/posterior pattern formation ; GO:0009952 | traceable author statement <newline> leg disc morphogenesis ; GO:0007478 | traceable author statement <newline> cell fate commitment ; GO:0045165 | non-traceable author statement <newline> negative regulation of fusion cell fate specification ; GO:0035157 | traceable author statement <newline> negative regulation of terminal cell fate specification, open tracheal system ; GO:0035155 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> imaginal disc growth ; GO:0007446 | traceable author statement <newline> imaginal disc pattern formation ; GO:0007447 | traceable author statement <newline> skeletal muscle tissue development ; GO:0007519 | inferred from mutant phenotype <newline> ovarian follicle cell stalk formation ; GO:0030713 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> germarium-derived egg chamber formation ; GO:0007293 | traceable author statement <newline> germarium-derived female germ-line cyst encapsulation ; GO:0030708 | traceable author statement <newline> morphogenesis of follicular epithelium ; GO:0016333 | non-traceable author statement <newline> oocyte anterior/posterior axis specification ; GO:0007314 | traceable author statement <newline> dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | traceable author statement <newline> establishment of ommatidial planar polarity ; GO:0042067 | non-traceable author statement <newline> cell fate specification ; GO:0001708 | non-traceable author statement <newline> compound eye retinal cell programmed cell death ; GO:0046667 | traceable author statement <newline> second mitotic wave during compound eye morphogenesis ; GO:0016330 | non-traceable author statement <newline> R8 cell differentiation ; GO:0045465 | non-traceable author statement <newline> regulation of R8 cell spacing in compound eye ; GO:0045468 | non-traceable author statement <newline> dorsal/ventral pattern formation, imaginal disc ; GO:0007450 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> lateral inhibition ; GO:0046331 | non-traceable author statement <newline> negative regulation of JNK cascade ; GO:0046329 | non-traceable author statement <newline> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | NOT non-traceable author statement <newline> establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement <newline> crystal cell differentiation ; GO:0042688 | inferred from mutant phenotype <newline> embryonic hemopoiesis ; GO:0035162 | inferred from mutant phenotype <newline> hemocyte proliferation ; GO:0035172 | inferred from mutant phenotype <newline> larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype <newline> R3/R4 cell fate commitment ; GO:0007464 | non-traceable author statement <newline> retinal cell programmed cell death ; GO:0046666 | traceable author statement <newline> wing disc proximal/distal pattern formation ; GO:0007473 | traceable author statement <newline> regulation of crystal cell differentiation ; GO:0042689 | traceable author statement <newline> asymmetric cell division ; GO:0008356 | traceable author statement <newline> ventral cord development ; GO:0007419 | non-traceable author statement <newline> R7 cell differentiation ; GO:0045466 | traceable author statement <newline> regulation of mitotic cell cycle ; GO:0007346 | traceable author statement <newline> lymph gland crystal cell differentiation ; GO:0035170 | traceable author statement <newline> embryonic crystal cell differentiation ; GO:0035165 | traceable author statement <newline> long-term memory ; GO:0007616 | traceable author statement <newline> lymph gland development ; GO:0048542 | inferred from mutant phenotype <newline> negative regulation of compound eye photoreceptor development ; GO:0045316 | inferred from mutant phenotype <newline> positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> compound eye cone cell fate commitment ; GO:0042676 | traceable author statement <newline> compound eye development ; GO:0048749 | non-traceable author statement <newline> compound eye development ; GO:0048749 | traceable author statement <newline> R8 cell fate commitment ; GO:0007460 | traceable author statement <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> heterophilic cell-cell adhesion ; GO:0007157 | inferred from mutant phenotype inferred from direct assay <newline> positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype <newline> lamellocyte differentiation ; GO:0035171 | inferred from mutant phenotype <newline> response to symbiont ; GO:0009608 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype <newline> negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype <newline> epithelial cell type specification, open tracheal system ; GO:0035153 | inferred from mutant phenotype <newline> glial cell migration ; GO:0008347 | inferred from mutant phenotype <newline> glial cell differentiation ; GO:0010001 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from direct assay <newline> positive regulation of S phase of mitotic cell cycle ; GO:0045750 | inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from genetic interaction with klg <newline> R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype <newline> R1/R6 cell differentiation ; GO:0048052 | inferred from mutant phenotype <newline> eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype <newline> regulation of cell differentiation ; GO:0045595 | inferred from mutant phenotype","intracellular ; GO:0005622 | inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> integral to membrane ; GO:0016021 | traceable author statement <newline> integral to plasma membrane ; GO:0005887 | non-traceable author statement <newline> intracellular ; GO:0005622 | non-traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | traceable author statement <newline> subapical complex ; GO:0035003 | inferred from direct assay <newline> adherens junction ; GO:0005912 | inferred from direct assay <newline> cytoplasmic vesicle ; GO:0031410 | colocalizes_with inferred from direct assay <newline> protein complex ; GO:0043234 | inferred from physical interaction with Su(H) <newline> integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR010660, InterPro:IPR011656","transmembrane receptor activity ; GO:0004888 | traceable author statement <newline> receptor activity ; GO:0004872 | non-traceable author statement <newline> transcription activator activity ; GO:0016563 | non-traceable author statement <newline> receptor activity ; GO:0004872 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with dx <newline> transmembrane receptor activity ; GO:0004888 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> protein binding ; GO:0005515 | inferred from physical interaction with shg <newline> transcription activator activity ; GO:0016563 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VVI3 <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9Y0H4 <newline> protein binding ; GO:0005515 | inferred from physical interaction with Su(H) <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097"]
[null,"FBgn0004657","myospheroid","mys","The gene myospheroid is referred to in FlyBase by the symbol Dmel\\mys (CG1560, FBgn0004657). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7955680..7964270. It has the cytological map location 7D5. It is reported to have molecular function</span>: cell adhesion molecule binding; receptor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; central nervous system development; germ-line stem cell maintenance; determination of adult lifespan; axon guidance; hemocyte migration; cell adhesion; muscle organ development; maintenance of epithelial integrity, open tracheal system; substrate-bound cell migration, cell extension. 141 alleles are reported. The phenotypes of these alleles are annotated with 55 unique terms, many of which group under: organ system; hypodermal muscle of larval abdomen; adult segment; primordium; nervous system; larval abdominal segment 5; adult mesothoracic segment; larval abdominal segment; extended germ band embryo; abdominal 7 longitudinal muscle; external compound sense organ. It has one annotated transcript and one annotated polypeptide.","central nervous system development ; GO:0007417 | inferred from mutant phenotype <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> cell migration ; GO:0016477 | traceable author statement <newline> midgut development ; GO:0007494 | traceable author statement <newline> muscle attachment ; GO:0016203 | traceable author statement <newline> calcium-dependent cell-cell adhesion ; GO:0016339 | traceable author statement <newline> calcium-dependent cell-matrix adhesion ; GO:0016340 | inferred from sequence or structural similarity <newline> cell-matrix adhesion ; GO:0007160 | traceable author statement <newline> heterophilic cell-cell adhesion ; GO:0007157 | traceable author statement <newline> apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | non-traceable author statement <newline> cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement <newline> tracheal outgrowth, open tracheal system ; GO:0007426 | traceable author statement <newline> maintenance of epithelial integrity, open tracheal system ; GO:0035160 | inferred from mutant phenotype <newline> hemocyte migration ; GO:0035099 | inferred from genetic interaction with Gef26 inferred from genetic interaction with R <newline> substrate-bound cell migration, cell extension ; GO:0006930 | inferred from genetic interaction with Gef26 <newline> determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> integrin-mediated signaling pathway ; GO:0007229 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812 <newline> cell-matrix adhesion ; GO:0007160 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812","focal adhesion ; GO:0005925 | inferred from sequence or structural similarity <newline> integrin complex ; GO:0008305 | inferred from sequence or structural similarity <newline> integrin complex ; GO:0008305 | non-traceable author statement <newline> cell leading edge ; GO:0031252 | inferred from direct assay <newline> integrin complex ; GO:0008305 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812","cell adhesion molecule binding ; GO:0050839 | traceable author statement <newline> receptor activity ; GO:0004872 | traceable author statement <newline> receptor activity ; GO:0004872 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812 <newline> binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812"]
[null,"FBgn0004885","tolkin","tok","The gene tolkin is referred to in FlyBase by the symbol Dmel\\tok (CG6863, FBgn0004885). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:20545419..20574855. It has the cytological map location 96A18-96A19. Based on sequence similarity, it is predicted to have molecular function</span>: metalloendopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: motor axon guidance; axon guidance; defasciculation of motor neuron axon; imaginal disc-derived wing vein morphogenesis; protein maturation by peptide bond cleavage. 35 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; nervous system; adult segment; multi-cell-component structure; adult mesothoracic segment; peripheral nervous system; embryonic nervous system; thoracic segment; abdominal segmental nerve; abdominal longitudinal muscle. It has 2 annotated transcripts and 2 annotated polypeptides.","imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> protein maturation by peptide bond cleavage ; GO:0051605 | inferred from direct assay <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> motor axon guidance ; GO:0008045 | inferred from mutant phenotype <newline> defasciculation of motor neuron axon ; GO:0007415 | inferred from mutant phenotype <newline> proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026","-","metalloendopeptidase activity ; GO:0004222 | inferred from sequence or structural similarity with UniProtKB:P13497 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097"]
[null,"FBgn0005672","spitz","spi","The gene spitz is referred to in FlyBase by the symbol Dmel\\spi (CG10334, FBgn0005672). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:19567899..19577324. It has the cytological map location 37F2. It is reported to have molecular function</span>: gurken receptor binding; epidermal growth factor receptor binding. There is experimental evidence that it is involved in the biological process</span>: oenocyte development; border follicle cell migration; stomatogastric nervous system development; spiracle morphogenesis, open tracheal system; negative regulation of apoptosis; determination of genital disc primordium; imaginal disc-derived wing morphogenesis; behavioral response to ethanol; peripheral nervous system development. 80 alleles are reported. The phenotypes of these alleles are annotated with 110 unique terms, many of which group under: peripheral nervous system; nervous system; organ system; external compound sense organ; embryonic nervous system; multi-cell-component structure; hypodermal muscle of larval abdomen; adult segment; cuticle; commissure. It has 7 annotated transcripts and 7 annotated polypeptides.","oenocyte development ; GO:0007438 | inferred from genetic interaction with abd-A AND inferred from mutant phenotype <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | traceable author statement <newline> positive regulation of epidermal growth factor receptor signaling pathway ; GO:0045742 | non-traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | non-traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | non-traceable author statement <newline> G2/M transition of mitotic cell cycle ; GO:0000086 | non-traceable author statement <newline> second mitotic wave during compound eye morphogenesis ; GO:0016330 | non-traceable author statement <newline> R8 cell-mediated photoreceptor organization ; GO:0045470 | non-traceable author statement <newline> anti-apoptosis ; GO:0006916 | non-traceable author statement <newline> negative regulation of compound eye retinal cell programmed cell death ; GO:0046673 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> determination of genital disc primordium ; GO:0035225 | inferred from mutant phenotype <newline> spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype <newline> stomatogastric nervous system development ; GO:0007421 | inferred from mutant phenotype","extracellular region ; GO:0005576 | traceable author statement <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> Golgi apparatus ; GO:0005794 | inferred from genetic interaction with S <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> integral to membrane ; GO:0016021 | non-traceable author statement <newline> endoplasmic reticulum ; GO:0005783 | non-traceable author statement <newline> extracellular region ; GO:0005576 | non-traceable author statement","epidermal growth factor receptor binding ; GO:0005154 | traceable author statement <newline> epidermal growth factor receptor binding ; GO:0005154 | non-traceable author statement <newline> gurken receptor binding ; GO:0008317 | non-traceable author statement"]
[null,"FBgn0010379","Akt1","Akt1","The gene Akt1 is referred to in FlyBase by the symbol Dmel\\Akt1 (CG4006, FBgn0010379). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11924938..11930239. It has the cytological map location 89B3. There is experimental evidence that it has the molecular function</span>: protein serine/threonine kinase activity; protein kinase activity. There is experimental evidence for 13 unique biological process</span> terms, many of which group under: regulation of biological process; regulation of developmental process; anatomical structure development; regulation of anatomical structure size; positive regulation of biological process; GO:0023034; biopolymer modification; lipid storage; regulation of apoptosis; regulation of neurogenesis; response to hormone stimulus. 30 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; organ system; external compound sense organ; adult mesothoracic segment; peripheral nervous system; thoracic segment; nervous system; wing hair; dorsal thoracic disc; synapse; embryonic trachea. It has 3 annotated transcripts and 3 annotated polypeptides.","anti-apoptosis ; GO:0006916 | inferred from mutant phenotype <newline> positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype <newline> positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement <newline> positive regulation of cell growth ; GO:0030307 | traceable author statement <newline> regulation of organ growth ; GO:0046620 | non-traceable author statement <newline> positive regulation of cell size ; GO:0045793 | traceable author statement <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> positive regulation of cell size ; GO:0045793 | non-traceable author statement <newline> positive regulation of organ growth ; GO:0046622 | non-traceable author statement <newline> insulin receptor signaling pathway ; GO:0008286 | non-traceable author statement <newline> positive regulation of cell growth ; GO:0030307 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> positive regulation of organ growth ; GO:0046622 | traceable author statement <newline> insulin receptor signaling pathway ; GO:0008286 | traceable author statement <newline> regulation of multicellular organism growth ; GO:0040014 | non-traceable author statement <newline> regulation of cell size ; GO:0008361 | non-traceable author statement <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from genetic interaction with Pi3K21B <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> regulation of protein import into nucleus ; GO:0042306 | traceable author statement <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> lipid storage ; GO:0019915 | inferred from genetic interaction with Pten <newline> positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype <newline> insulin receptor signaling pathway ; GO:0008286 | inferred from genetic interaction with UniProtKB:P91634 <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay <newline> regulation of dendrite development ; GO:0050773 | inferred from mutant phenotype <newline> regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype <newline> positive regulation of organ growth ; GO:0046622 | inferred from mutant phenotype <newline> intracellular signaling pathway ; GO:0023034 | inferred from genetic interaction with UniProtKB:P91634","plasma membrane ; GO:0005886 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> cell surface ; GO:0009986 | inferred from direct assay","protein kinase activity ; GO:0004672 | inferred from direct assay <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from mutant phenotype <newline> protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement <newline> phosphoinositide binding ; GO:0035091 | non-traceable author statement <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR015744, InterPro:IPR017441, InterPro:IPR017442, InterPro:IPR017892"]
[null,"FBgn0010434","coracle","cora","The gene coracle is referred to in FlyBase by the symbol Dmel\\cora (CG11949, FBgn0010434). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15116570..15131256. It has the cytological map location 56C4. Based on sequence similarity, it is predicted to have molecular function</span>: cytoskeletal protein binding. There is experimental evidence that it is involved in the biological process</span>: embryonic morphogenesis; maintenance of imaginal disc-derived wing hair orientation; regulation of tube size, open tracheal system; establishment of glial blood-brain barrier. 42 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: peripheral nervous system; organ system; nervous system; external compound sense organ; plasma membrane part; integumentary plate; plasma membrane; embryonic head; embryonic dorsal trunk; wing hair; embryonic tracheal system. It has 4 annotated transcripts and 4 annotated polypeptides.","embryonic morphogenesis ; GO:0048598 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | traceable author statement <newline> salivary gland morphogenesis ; GO:0007435 | traceable author statement <newline> septate junction assembly ; GO:0019991 | traceable author statement <newline> protein targeting to membrane ; GO:0006612 | traceable author statement <newline> regulation of tube size, open tracheal system ; GO:0035151 | inferred from mutant phenotype <newline> maintenance of imaginal disc-derived wing hair orientation ; GO:0035321 | inferred from mutant phenotype <newline> cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity with EMBL:AB019257; protein_id:BAA76625.1 <newline> embryonic development ; GO:0009790 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | non-traceable author statement <newline> cell-cell junction organization ; GO:0045216 | traceable author statement <newline> establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement <newline> establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype","septate junction ; GO:0005918 | inferred from direct assay <newline> fusome ; GO:0045169 | NOT inferred from direct assay <newline> spectrosome ; GO:0045170 | NOT inferred from direct assay <newline> septate junction ; GO:0005918 | traceable author statement <newline> septate junction ; GO:0005918 | non-traceable author statement <newline> cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity with EMBL:AB019257; protein_id:BAA76625.1 <newline> apicolateral plasma membrane ; GO:0016327 | non-traceable author statement","cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity <newline> actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR008379 <newline> structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR008379"]
[null,"FBgn0010762","simjang","simj","The gene simjang is referred to in FlyBase by the symbol Dmel\\simj (CG32067, FBgn0010762). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:10657843..10682480. It has the cytological map location 67E6. Based on sequence similarity, it is predicted to have molecular function</span>: transcription repressor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: negative regulation of transcription, DNA-dependent. 51 alleles are reported. The phenotypes of these alleles are annotated with: leg; embryonic heart; scutellar bristle; wing; cardioblast; pupal abdomen. It has 3 annotated transcripts and 3 annotated polypeptides.","negative regulation of transcription, DNA-dependent ; GO:0045892 | inferred from sequence or structural similarity with EMBL:AF411837; protein_id:AAL39081.1","nucleus ; GO:0005634 | inferred from direct assay","transcription repressor activity ; GO:0016564 | inferred from sequence or structural similarity with EMBL:AF411837; protein_id:AAL39081.1"]
[null,"FBgn0011224","hephaestus","heph","The gene hephaestus is referred to in FlyBase by the symbol Dmel\\heph (CG31000, FBgn0011224). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27676704..27819000. It has the cytological map location 100D3-100E1. There is experimental evidence that it has the molecular function</span>: mRNA 3'-UTR binding; translation repressor activity, nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: spermatid development; imaginal disc-derived wing margin morphogenesis; oocyte microtubule cytoskeleton polarization; imaginal disc-derived wing vein morphogenesis; Notch signaling pathway; negative regulation of oskar mRNA translation. 106 alleles are reported. The phenotypes of these alleles are annotated with: macrochaeta; testis; wing; individualization stage spermatid; spermatozoon. It has 22 annotated transcripts and 22 annotated polypeptides.","spermatid development ; GO:0007286 | inferred from mutant phenotype <newline> nuclear mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with NCBI_NP:002810 <newline> Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> negative regulation of oskar mRNA translation ; GO:0007319 | inferred from mutant phenotype <newline> oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay <newline> ribonucleoprotein complex ; GO:0030529 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR006536","poly-pyrimidine tract binding ; GO:0008187 | non-traceable author statement <newline> mRNA binding ; GO:0003729 | inferred from sequence or structural similarity <newline> poly-pyrimidine tract binding ; GO:0008187 | inferred from sequence or structural similarity with NCBI_NP:002810 <newline> mRNA 3'-UTR binding ; GO:0003730 | inferred from direct assay <newline> translation repressor activity, nucleic acid binding ; GO:0000900 | inferred from mutant phenotype <newline> nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR012677"]
[null,"FBgn0011591","fringe","fng","The gene fringe is referred to in FlyBase by the symbol Dmel\\fng (CG10580, FBgn0011591). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20918983..20942609. It has the cytological map location 78A1. There is experimental evidence that it has the molecular function</span>: UDP-glycosyltransferase activity; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity; acetylglucosaminyltransferase activity. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; organ morphogenesis; regulation of biological process; leg morphogenesis; sensory organ development; leg segmentation; biopolymer modification; hexose metabolic process; regionalization; appendage development; compound eye development. 66 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; female germline cyst; late extended germ band embryo; nervous system; ectoderm derivative; external compound sense organ; primordium. It has one annotated transcript and one annotated polypeptide.","imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> dorsal/ventral pattern formation, imaginal disc ; GO:0007450 | inferred from direct assay <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from direct assay <newline> leg joint morphogenesis ; GO:0035111 | inferred from mutant phenotype <newline> leg segmentation ; GO:0035286 | inferred from mutant phenotype <newline> Notch signaling pathway ; GO:0007219 | inferred from direct assay <newline> fucose metabolic process ; GO:0006004 | inferred from direct assay <newline> germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype <newline> regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype <newline> positive regulation of Notch signaling pathway ; GO:0045747 | non-traceable author statement <newline> Notch signaling pathway ; GO:0007219 | traceable author statement <newline> dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | traceable author statement <newline> regulation of Notch signaling pathway ; GO:0008593 | traceable author statement <newline> negative regulation of Notch signaling pathway ; GO:0045746 | non-traceable author statement <newline> regulation of Notch signaling pathway ; GO:0008593 | non-traceable author statement <newline> cell fate specification ; GO:0001708 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from direct assay <newline> oogenesis ; GO:0048477 | traceable author statement <newline> regulation of Notch signaling pathway ; GO:0008593 | inferred from direct assay <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> protein amino acid O-linked glycosylation ; GO:0006493 | inferred from mutant phenotype <newline> fucose metabolic process ; GO:0006004 | inferred from mutant phenotype","Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> Golgi apparatus ; GO:0005794 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | non-traceable author statement <newline> Golgi stack ; GO:0005795 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> Golgi apparatus ; GO:0005794 | traceable author statement <newline> integral to Golgi membrane ; GO:0030173 | inferred from electronic annotation with InterPro:IPR017374","UDP-glycosyltransferase activity ; GO:0008194 | inferred from direct assay <newline> acetylglucosaminyltransferase activity ; GO:0008375 | inferred from direct assay <newline> acetylglucosaminyltransferase activity ; GO:0008375 | non-traceable author statement <newline> acetylglucosaminyltransferase activity ; GO:0008375 | traceable author statement <newline> O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity ; GO:0033829 | inferred from direct assay"]
[null,"FBgn0011766","E2F transcription factor","E2f","The gene E2F transcription factor is referred to in FlyBase by the symbol Dmel\\E2f (CG6376, FBgn0011766). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17446026..17486127. It has the cytological map location 93E9-93F1. There is experimental evidence that it has the molecular function</span>: protein binding; RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of gene expression; cellular process; dendrite morphogenesis; neuron development; positive regulation of nurse cell apoptosis; muscle tissue development; antimicrobial humoral response; regulation of cell cycle; DNA endoreduplication. 70 alleles are reported. The phenotypes of these alleles are annotated with 31 unique terms, many of which group under: organ system; peripheral nervous system; nervous system; external compound sense organ; female germline cyst; egg; imaginal precursor; adult segment; cell part; primordium; adult mesothoracic segment. It has 3 annotated transcripts and 3 annotated polypeptides.","positive regulation of cell proliferation ; GO:0008284 | non-traceable author statement <newline> positive regulation of nurse cell apoptosis ; GO:0045850 | inferred from mutant phenotype <newline> DNA endoreduplication ; GO:0042023 | inferred from genetic interaction with CycE AND inferred from mutant phenotype <newline> eggshell chorion gene amplification ; GO:0007307 | traceable author statement <newline> G1/S transition of mitotic cell cycle ; GO:0000082 | traceable author statement <newline> imaginal disc development ; GO:0007444 | traceable author statement <newline> nurse cell apoptosis ; GO:0045476 | traceable author statement <newline> positive regulation of transcription ; GO:0045941 | traceable author statement <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> regulation of transcription involved in G1/S-phase of mitotic cell cycle ; GO:0000083 | non-traceable author statement <newline> growth ; GO:0040007 | non-traceable author statement <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | non-traceable author statement <newline> positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> muscle tissue development ; GO:0060537 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003316","nucleus ; GO:0005634 | inferred from direct assay <newline> Rb-E2F complex ; GO:0035189 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","DNA binding ; GO:0003677 | inferred from direct assay <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with Rbf <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription activator activity ; GO:0016563 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with dom inferred from physical interaction with l(3)mbt <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR003316"]
[null,"FBgn0013263","Trithorax-like","Trl","The gene Trithorax-like is referred to in FlyBase by the symbol Dmel\\Trl (CG33261, FBgn0013263). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14741029..14754149. It has the cytological map location 70F4. There is experimental evidence that it has the molecular function</span>: protein binding; specific RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: cellular process; dosage compensation; nuclear division; syncytial blastoderm mitotic cell cycle; imaginal disc-derived wing morphogenesis; protein oligomerization. 68 alleles are reported. The phenotypes of these alleles are annotated with: eye; abdominal segment 6; egg; sex comb; micropyle; wing; imaginal disc; egg chamber; chromatin; denticle belt. It has 9 annotated transcripts and 9 annotated polypeptides.","nuclear division ; GO:0000280 | inferred from mutant phenotype <newline> syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | non-traceable author statement <newline> chromatin organization ; GO:0006325 | non-traceable author statement <newline> dosage compensation ; GO:0007549 | inferred from mutant phenotype <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> positive regulation of transcription, DNA-dependent ; GO:0045893 | traceable author statement <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> protein oligomerization ; GO:0051259 | inferred from direct assay","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> centromeric heterochromatin ; GO:0005721 | inferred from direct assay AND traceable author statement <newline> chromatin ; GO:0000785 | non-traceable author statement","DNA binding ; GO:0003677 | non-traceable author statement <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from mutant phenotype <newline> protein binding ; GO:0005515 | inferred from physical interaction with Ssrp <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P17789 <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P41046 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0014184","Ornithine decarboxylase antizyme","Oda","The gene Ornithine decarboxylase antizyme is referred to in FlyBase by the symbol Dmel\\Oda (CG16747, FBgn0014184). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8054077..8061767. It has the cytological map location 48E4. Based on sequence similarity, it is predicted to have molecular function</span>: ornithine decarboxylase inhibitor activity. It is reported to be involved in the biological process</span>: cell differentiation. 25 alleles are reported. The phenotypes of these alleles are annotated with: larval salivary gland; lymph gland; dorsal mesothoracic disc; dorsal metathoracic disc; imaginal disc; embryonic/larval brain; ventral thoracic disc; salivary gland imaginal ring. It has 3 annotated transcripts and 3 annotated polypeptides.","cell differentiation ; GO:0030154 | non-traceable author statement","-","ornithine decarboxylase inhibitor activity ; GO:0008073 | inferred from sequence or structural similarity with HGNC_gene:OAZ1; HGNC:8095; OMIM:601579 <newline> ornithine decarboxylase inhibitor activity ; GO:0008073 | non-traceable author statement"]
[null,"FBgn0015218","Eukaryotic initiation factor 4E","eIF-4E","The gene Eukaryotic initiation factor 4E is referred to in FlyBase by the symbol Dmel\\eIF-4E (CG4035, FBgn0015218). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9392716..9395565. It has the cytological map location 67B4. There is experimental evidence that it has the molecular function</span>: translation initiation factor activity; RNA cap binding. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: cell cycle; cell cycle process; organelle organization; programmed cell death; cellular macromolecule metabolic process; nuclear division; biopolymer biosynthetic process; gland morphogenesis; chromatin organization; cell death; chromosome organization; regulation of biological process. 38 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: nervous system; organ system; peripheral nervous system; external compound sense organ; thoracic segment; cell component; cell cycle; dorsal thoracic disc; multi-cell-component structure; eipithelial furrow; neuromuscular junction; adult segment. It has 7 annotated transcripts and 7 annotated polypeptides.","translation ; GO:0006412 | inferred from sequence or structural similarity with HGNC_gene:EIF4E; HGNC:3287; OMIM:133440 AND inferred from sequence or structural similarity with MGD:Eif4e; MGI:MGI:95305 <newline> RNA metabolic process ; GO:0016070 | inferred from direct assay <newline> translational initiation ; GO:0006413 | inferred from direct assay <newline> translation ; GO:0006412 | non-traceable author statement <newline> positive regulation of cell growth ; GO:0030307 | traceable author statement <newline> regulation of cell growth ; GO:0001558 | inferred from mutant phenotype <newline> RNA metabolic process ; GO:0016070 | non-traceable author statement <newline> translational initiation ; GO:0006413 | non-traceable author statement <newline> chromatin organization ; GO:0006325 | inferred from mutant phenotype <newline> female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype <newline> mitosis ; GO:0007067 | inferred from mutant phenotype <newline> mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype","cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC_gene:EIF4E; HGNC:3287; OMIM:133440 AND inferred from sequence or structural similarity with MGD:Eif4e; MGI:MGI:95305 <newline> eukaryotic translation initiation factor 4F complex ; GO:0016281 | non-traceable author statement <newline> cytosol ; GO:0005829 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> cytosol ; GO:0005829 | inferred from sequence or structural similarity <newline> eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity <newline> postsynaptic density ; GO:0014069 | inferred from direct assay <newline> cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with HGNC_gene:EIF4E; HGNC:3287; OMIM:133440 AND inferred from sequence or structural similarity with MGD:Eif4e; MGI:MGI:95305 <newline> RNA cap binding ; GO:0000339 | inferred from direct assay <newline> translation initiation factor activity ; GO:0003743 | inferred from direct assay <newline> translation initiation factor activity ; GO:0003743 | non-traceable author statement <newline> RNA cap binding ; GO:0000339 | inferred from sequence or structural similarity <newline> translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity <newline> RNA cap binding ; GO:0000339 | non-traceable author statement"]
[null,"FBgn0015919","caupolican","caup","The gene caupolican is referred to in FlyBase by the symbol Dmel\\caup (CG10605, FBgn0015919). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:12603226..12614908. It has the cytological map location 69D1. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity, enhancer binding; transcription activator activity. There is experimental evidence that it is involved in the biological process</span>: imaginal disc-derived wing vein specification; compound eye morphogenesis; phagocytosis, engulfment. 13 alleles are reported. The phenotypes of these alleles are annotated with: mesothoracic segment; eye; macrochaeta; notopleural suture; vertical bristle; wing; microchaeta; ommatidium; scutellum. It has one annotated transcript and one annotated polypeptide.","equator specification ; GO:0045317 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from genetic interaction with ara <newline> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with ara","nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC_gene:PBX1; HGNC:8632; OMIM:176310","specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> transcription regulator activity ; GO:0030528 | non-traceable author statement <newline> RNA polymerase II transcription factor activity, enhancer binding ; GO:0003705 | inferred from sequence or structural similarity with ara <newline> transcription activator activity ; GO:0016563 | inferred from sequence or structural similarity with ara"]
[null,"FBgn0016797","frizzled 2","fz2","The gene frizzled 2 is referred to in FlyBase by the symbol Dmel\\fz2 (CG9739, FBgn0016797). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19135998..19228191. It has the cytological map location 75F9-76A3. There is experimental evidence that it has the molecular function</span>: Wnt receptor activity; protein binding; PDZ domain binding; Wnt-protein binding. There is experimental evidence that it is involved in the biological process</span>: female gonad development; cellular component movement; imaginal disc-derived wing margin morphogenesis; receptor-mediated endocytosis; bristle morphogenesis; Wnt receptor signaling pathway; axon extension; salivary gland morphogenesis; Wnt receptor signaling pathway, calcium modulating pathway; synapse organization. 112 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; adult segment; nervous system; adult mesothoracic segment; external compound sense organ; peripheral nervous system; cell component; cuticle; t-bar; embryonic neuron; postsynaptic membrane; neuromuscular junction. It has 4 annotated transcripts and 4 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from direct assay <newline> establishment or maintenance of cell polarity ; GO:0007163 | inferred from sequence or structural similarity <newline> Wnt receptor signaling pathway, calcium modulating pathway ; GO:0007223 | inferred from direct assay <newline> cellular component movement ; GO:0006928 | inferred from mutant phenotype <newline> female gonad development ; GO:0008585 | inferred from mutant phenotype <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> receptor-mediated endocytosis ; GO:0006898 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from sequence or structural similarity <newline> Wnt receptor signaling pathway ; GO:0016055 | non-traceable author statement <newline> axon extension ; GO:0048675 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> synapse organization ; GO:0050808 | inferred from physical interaction with Grip <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype","integral to membrane ; GO:0016021 | non-traceable author statement <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> early endosome ; GO:0005769 | colocalizes_with inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> late endosome ; GO:0005770 | colocalizes_with inferred from direct assay","Wnt receptor activity ; GO:0042813 | inferred from direct assay <newline> Wnt-protein binding ; GO:0017147 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from direct assay <newline> transmembrane receptor activity ; GO:0004888 | inferred from sequence or structural similarity <newline> Wnt receptor activity ; GO:0042813 | non-traceable author statement <newline> PDZ domain binding ; GO:0030165 | inferred from physical interaction with Grip <newline> non-G-protein coupled 7TM receptor activity ; GO:0004926 | inferred from electronic annotation with InterPro:IPR000539"]
[null,"FBgn0020245","tout-velu","ttv","The gene tout-velu is referred to in FlyBase by the symbol Dmel\\ttv (CG10117, FBgn0020245). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10414076..10472826. It has the cytological map location 51A7-51B4. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: decapentaplegic receptor signaling pathway; smoothened signaling pathway; glycosaminoglycan biosynthetic process; regulation of smoothened signaling pathway; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; germ cell migration; Wnt receptor signaling pathway; heparin biosynthetic process; heparan sulfate proteoglycan biosynthetic process. 64 alleles are reported. The phenotypes of these alleles are annotated with: dorsal mesothoracic disc; cuticle; macrochaeta; germline cell; denticle belt. It has one annotated transcript and one annotated polypeptide.","germ cell migration ; GO:0008354 | inferred from mutant phenotype <newline> regulation of smoothened signaling pathway ; GO:0008589 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | non-traceable author statement <newline> heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | inferred from genetic interaction with Ext2 <newline> decapentaplegic receptor signaling pathway ; GO:0008101 | inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | traceable author statement <newline> glycosaminoglycan biosynthetic process ; GO:0006024 | inferred from mutant phenotype <newline> heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process ; GO:0015014 | non-traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | non-traceable author statement <newline> Wnt receptor signaling pathway ; GO:0016055 | inferred from mutant phenotype <newline> heparin biosynthetic process ; GO:0030210 | inferred from mutant phenotype <newline> N-acetylglucosamine metabolic process ; GO:0006044 | inferred from sequence or structural similarity with UniProtKB:O77783 <newline> heparan sulfate proteoglycan biosynthetic process ; GO:0015012 | inferred from direct assay","integral to membrane ; GO:0016021 | non-traceable author statement <newline> Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> intrinsic to endoplasmic reticulum membrane ; GO:0031227 | inferred from electronic annotation with InterPro:IPR015338","acetylglucosaminyltransferase activity ; GO:0008375 | inferred from sequence or structural similarity with EMBL:AF089748 <newline> acetylglucosaminyltransferase activity ; GO:0008375 | non-traceable author statement <newline> glucuronosyltransferase activity ; GO:0015020 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with Ext2 <newline> N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity ; GO:0050509 | inferred from sequence or structural similarity with UniProtKB:O77783 <newline> glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity ; GO:0050508 | inferred from sequence or structural similarity with UniProtKB:O77783"]
[null,"FBgn0020249","steamer duck","stck","The gene steamer duck is referred to in FlyBase by the symbol Dmel\\stck (CG7954, FBgn0020249). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4182689..4185745. It has the cytological map location 84F15. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. There is experimental evidence that it is involved in the biological process</span>: dorsal closure; apposition of dorsal and ventral imaginal disc-derived wing surfaces; embryonic pattern specification; negative regulation of JNK cascade; head involution. 14 alleles are reported. The phenotypes of these alleles are annotated with: larva; embryonic somatic muscle; embryonic/larval somatic muscle. It has 3 annotated transcripts and 3 annotated polypeptides.","apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> negative regulation of JNK cascade ; GO:0046329 | inferred from genetic interaction with msn <newline> embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype <newline> head involution ; GO:0008258 | inferred from mutant phenotype","cell leading edge ; GO:0031252 | inferred from direct assay","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781"]
[null,"FBgn0022720","Zinc finger protein 30C","zf30C","The gene Zinc finger protein 30C is referred to in FlyBase by the symbol Dmel\\zf30C (CG3998, FBgn0022720). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:9758338..9762377. It has the cytological map location 30C7. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: neuron development. 6 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; wing margin; posterior crossvein; wing; wing vein L2. It has one annotated transcript and one annotated polypeptide.","neuron development ; GO:0048666 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:U27186","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:U27186 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0023001","melted","melt","The gene melted is referred to in FlyBase by the symbol Dmel\\melt (CG8624, FBgn0023001). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:7127618..7136174. It has the cytological map location 65E4-65E5. There is experimental evidence that it has the molecular function</span>: specific transcriptional repressor activity; phosphoinositide binding; phosphatidylinositol-5-phosphate binding. There is experimental evidence that it is involved in the biological process</span>: insulin receptor signaling pathway; ectoderm development; sequestering of triglyceride; R8 cell fate specification; peripheral nervous system development. 17 alleles are reported. The phenotypes of these alleles are annotated with: photoreceptor cell R8 of yellow ommatidium; embryonic peripheral nervous system; embryonic nervous system; wing. It has 2 annotated transcripts and 2 annotated polypeptides.","sequestering of triglyceride ; GO:0030730 | inferred from mutant phenotype <newline> insulin receptor signaling pathway ; GO:0008286 | inferred from mutant phenotype <newline> ectoderm development ; GO:0007398 | inferred from expression pattern <newline> peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype <newline> R8 cell fate specification ; GO:0045464 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from direct assay","phosphoinositide binding ; GO:0035091 | inferred from direct assay <newline> phosphatidylinositol-5-phosphate binding ; GO:0010314 | inferred from direct assay <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype"]
[null,"FBgn0023215","Mnt","Mnt","The gene Mnt is referred to in FlyBase by the symbol Dmel\\Mnt (CG13316, FBgn0023215). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3565834..3594813. It has the cytological map location 3E4-3E5. There is experimental evidence that it has the molecular function</span>: protein binding; sequence-specific DNA binding; transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription; regulation of cell cycle; negative regulation of cell growth; phagocytosis, engulfment. 32 alleles are reported. The phenotypes of these alleles are annotated with: eye; adult head; ommatidium; wing hair. It has 7 annotated transcripts and 7 annotated polypeptides.","regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with dm <newline> regulation of transcription ; GO:0045449 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> negative regulation of cell growth ; GO:0030308 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity <newline> nucleus ; GO:0005634 | inferred by curator from GO:0003700 <newline> nucleus ; GO:0005634 | inferred from direct assay","RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with dm <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q99583 <newline> protein binding ; GO:0005515 | inferred from physical interaction with Max <newline> sequence-specific DNA binding ; GO:0043565 | inferred from direct assay <newline> transcription repressor activity ; GO:0016564 | inferred from direct assay"]
[null,"FBgn0024250","brinker","brk","The gene brinker is referred to in FlyBase by the symbol Dmel\\brk (CG9653, FBgn0024250). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7201974..7205165. It has the cytological map location 7B1. There is experimental evidence that it has the molecular function</span>: specific transcriptional repressor activity. There is experimental evidence that it is involved in the biological process</span>: wing disc morphogenesis; cell competition in a multicellular organism; negative regulation of transforming growth factor beta receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; imaginal disc-derived wing morphogenesis. 65 alleles are reported. The phenotypes of these alleles are annotated with 36 unique terms, many of which group under: organ system; primordium; adult segment; embryonic nervous system; adult mesothoracic segment; ventral nerve cord primordium; portion of tissue; somatic stem cell; peripheral nervous system; thoracic segment. It has one annotated transcript and one annotated polypeptide.","negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype <newline> negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | inferred from mutant phenotype <newline> wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | traceable author statement <newline> regulation of BMP signaling pathway ; GO:0030510 | traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | non-traceable author statement <newline> negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | non-traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with dsx <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype"]
[null,"FBgn0024555","falafel","flfl","The gene falafel is referred to in FlyBase by the symbol Dmel\\flfl (CG9351, FBgn0024555). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:9509680..9519629. It has the cytological map location 87F10-87F11. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: Rac protein signal transduction; dorsal closure; neuroblast proliferation; phagocytosis, engulfment. 20 alleles are reported. The phenotypes of these alleles are annotated with: neuroblast; wing; cell; wing vein. It has 2 annotated transcripts and 2 annotated polypeptides.","Rac protein signal transduction ; GO:0016601 | inferred from genetic interaction with Rac1 <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> asymmetric neuroblast division ; GO:0055059 | inferred from electronic annotation <newline> neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype","-","-"]
[null,"FBgn0026160","tonalli","tna","The gene tonalli is referred to in FlyBase by the symbol Dmel\\tna (CG7958, FBgn0026160). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:10828628..10867746. It has the cytological map location 67F1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. There is experimental evidence that it is involved in the biological process</span>: chromatin-mediated maintenance of transcription. 15 alleles are reported. The phenotypes of these alleles are annotated with: haltere; sex comb; wing. It has 4 annotated transcripts and 4 annotated polypeptides.","chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from genetic interaction with Antp AND inferred from genetic interaction with Pc AND inferred from genetic interaction with Scr AND inferred from genetic interaction with brm AND inferred from genetic interaction with kis AND inferred from genetic interaction with osa","-","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR004181"]
[null,"FBgn0039350","jing interacting gene regulatory 1","jigr1","The gene jing interacting gene regulatory 1 is referred to in FlyBase by the symbol Dmel\\jigr1 (CG17383, FBgn0039350). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21463549..21475972. It has the cytological map location 96E6. Its molecular function is unknown. The biological processes in which it is involved are not known. 24 alleles are reported. The phenotypes of these alleles are annotated with: wing; larval central nervous system. It has 6 annotated transcripts and 6 annotated polypeptides.","-","-","-"]
[null,"FBgn0040071","taranis","tara","The gene taranis is referred to in FlyBase by the symbol Dmel\\tara (CG6889, FBgn0040071). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12051371..12086024. It has the cytological map location 89B8-89B9. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: wing disc dorsal/ventral pattern formation; chromatin-mediated maintenance of transcription. 93 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; trichogen cell; macrochaeta; haltere; tormogen cell; scutellar bristle; wing; arista. It has 2 annotated transcripts and 2 annotated polypeptides.","chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from genetic interaction with Pc AND inferred from genetic interaction with brm AND inferred from genetic interaction with osa AND inferred from genetic interaction with pb AND inferred from genetic interaction with ph-p AND inferred from genetic interaction with trx <newline> chromatin-mediated maintenance of transcription ; GO:0048096 | inferred from genetic interaction with brm AND inferred from genetic interaction with osa AND inferred from genetic interaction with tna <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap","-","-"]
[null,"FBgn0041604","dally-like","dlp","The gene dally-like is referred to in FlyBase by the symbol Dmel\\dlp (CG32146, FBgn0041604). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14625720..14664716. It has the cytological map location 70E5-70E7. It is reported to have molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; detection of light stimulus involved in visual perception; axon guidance; compound eye development; imaginal disc-derived wing margin morphogenesis; wing disc dorsal/ventral pattern formation; positive regulation of smoothened signaling pathway; Wnt receptor signaling pathway; regulation of imaginal disc growth; segment polarity determination. 39 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; peripheral nervous system; adult mesothoracic segment; external compound sense organ; organ system; nervous system; cuticle; lamina plexus; dorsal thoracic disc; compound cell cluster organ. It has 2 annotated transcripts and 2 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from genetic interaction with dally AND inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> decapentaplegic receptor signaling pathway ; GO:0008101 | non-traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | traceable author statement <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from expression pattern AND inferred from genetic interaction with wg <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> detection of light stimulus involved in visual perception ; GO:0050908 | inferred from mutant phenotype <newline> positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype <newline> regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype","extracellular region ; GO:0005576 | inferred from sequence or structural similarity <newline> proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR001863 <newline> membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001863","protein binding ; GO:0005515 | non-traceable author statement <newline> heparan sulfate proteoglycan binding ; GO:0043395 | inferred from electronic annotation with InterPro:IPR001863"]
[null,"FBgn0053196","dumpy","dp","The gene dumpy is referred to in FlyBase by the symbol Dmel\\dp (CG33196, FBgn0053196). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:4479471..4591963. It has the cytological map location 24F4-25A1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: 4 iron, 4 sulfur cluster binding; serine-type endopeptidase inhibitor activity; endonuclease activity; calcium ion binding. There is experimental evidence that it is involved in the biological process</span>: apposition of dorsal and ventral imaginal disc-derived wing surfaces; chitin-based cuticle attachment to epithelium; open tracheal system development; chitin-based embryonic cuticle biosynthetic process. 270 alleles are reported. The phenotypes of these alleles are annotated with 20 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; embryonic/larval tracheal system; portion of tissue; peripheral nervous system; nervous system; lateral trunk posterior branch; adult trachea; embryonic tracheal system; tracheal system. It has one annotated transcript and one annotated polypeptide.","chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype <newline> chitin-based cuticle attachment to epithelium ; GO:0040005 | inferred from mutant phenotype <newline> apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype","proteinaceous extracellular matrix ; GO:0005578 | non-traceable author statement","endonuclease activity ; GO:0004519 | inferred from electronic annotation with InterPro:IPR003651 <newline> 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR003651 <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097 <newline> serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from electronic annotation with InterPro:IPR000737"]
[null,"FBgn0085424","nubbin","nub","The gene nubbin is referred to in FlyBase by the symbol Dmel\\nub (CG34395, FBgn0085424). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12587871..12628143. It has the cytological map location 33F1. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: regulation of transcription from RNA polymerase II promoter. 25 alleles are reported. The phenotypes of these alleles are annotated with 53 unique terms, many of which group under: adult segment; synaptic neuropil subdomain; antennal segment; adult mesothoracic segment; multi-cell-component structure; embryonic neuron; antennal ORN; embryonic nervous system; larval abdominal segment; larval thorax; integumentary specialisation. It has 2 annotated transcripts and 2 annotated polypeptides.","pattern specification process ; GO:0007389 | non-traceable author statement <newline> neuroblast fate determination ; GO:0007400 | non-traceable author statement <newline> ventral cord development ; GO:0007419 | non-traceable author statement <newline> ganglion mother cell fate determination ; GO:0007402 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with NCBI_gi:4505957","nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with NCBI_gi:4505957","transcription factor activity ; GO:0003700 | non-traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity with NCBI_gi:4505957 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000327, InterPro:IPR001356"]
[null,"FBgn0085432","pangolin","pan","The gene pangolin is referred to in FlyBase by the symbol Dmel\\pan (CG34403, FBgn0085432). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:89956..129430. It has the cytological map location 102A3-102A4. There is experimental evidence that it has the molecular function</span>: specific transcriptional repressor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of Wnt receptor signaling pathway; spiracle morphogenesis, open tracheal system; embryonic pattern specification; regulation of hemocyte differentiation; imaginal disc-derived wing morphogenesis; positive regulation of transcription; salivary gland morphogenesis. 44 alleles are reported. The phenotypes of these alleles are annotated with 39 unique terms, many of which group under: organ system; adult segment; late extended germ band embryo; thoracic segment; muscle founder cell; peripheral nervous system; embryonic/larval tracheal system; adult mesothoracic segment; dorsal thoracic disc; spiracle. It has 10 annotated transcripts and 10 annotated polypeptides.","embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from sequence or structural similarity with MGD:Tcf7l2; MGI:MGI:1202879 <newline> segment polarity determination ; GO:0007367 | non-traceable author statement <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> mesodermal cell fate determination ; GO:0007500 | traceable author statement <newline> regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype <newline> spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | non-traceable author statement <newline> regulation of Wnt receptor signaling pathway ; GO:0030111 | inferred from mutant phenotype <newline> negative regulation of Wnt receptor signaling pathway ; GO:0030178 | non-traceable author statement <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> positive regulation of transcription ; GO:0045941 | inferred from mutant phenotype","transcription factor complex ; GO:0005667 | inferred from sequence or structural similarity with MGD:Tcf7l2; MGI:MGI:1202879 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000910"]
[null,"FBgn0259878","Follistatin","Fs","The gene Follistatin is referred to in FlyBase by the symbol Dmel\\Fs (CG33466, FBgn0259878). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11111061..11129084. It has the cytological map location 51E7-51E10. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: negative regulation of decapentaplegic receptor signaling pathway; positive regulation of activin receptor signaling pathway; negative regulation of activin receptor signaling pathway. 6 alleles are reported. The phenotypes of these alleles are annotated with: pupa; air bubble; ISNb; wing; larval optic lobe; anterior pupal spiracle. It has one annotated transcript and one annotated polypeptide.","negative regulation of activin receptor signaling pathway ; GO:0032926 | inferred from direct assay <newline> negative regulation of decapentaplegic receptor signaling pathway ; GO:0090099 | inferred from direct assay <newline> positive regulation of activin receptor signaling pathway ; GO:0032927 | inferred from direct assay","extracellular region ; GO:0005576 | inferred from direct assay","-"]
[null,"FBgn0259986","nab","nab","The gene nab is referred to in FlyBase by the symbol Dmel\\nab (CG33545, FBgn0259986). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4153618..4160932. It has the cytological map location 64A8. There is experimental evidence that it has the molecular function</span>: transcription cofactor activity. There is experimental evidence that it is involved in the biological process</span>: locomotory behavior; neuron development; wing disc pattern formation. 18 alleles are reported. The phenotypes of these alleles are annotated with: tarsal segment 2; eye; tarsal segment 4; tarsal segment 3; ommatidium; wing hinge; EL neuron; pigment cell. It has 2 annotated transcripts and 2 annotated polypeptides.","locomotory behavior ; GO:0007626 | inferred from mutant phenotype <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:Q62722 <newline> wing disc pattern formation ; GO:0035222 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q62722","transcription cofactor activity ; GO:0003712 | inferred from mutant phenotype inferred from physical interaction with rn inferred from physical interaction with sqz inferred from genetic interaction with rn inferred from genetic interaction with sqz <newline> transcription factor binding ; GO:0008134 | inferred from sequence or structural similarity with EMBL:U47543 <newline> transcription repressor activity ; GO:0016564 | inferred from sequence or structural similarity with UniProtKB:Q62722"]
[null,"FBgn0260003","Dystrophin","Dys","The gene Dystrophin is referred to in FlyBase by the symbol Dmel\\Dys (CG34157, FBgn0260003). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:15286810..15421117. It has the cytological map location 92A5-92A10. There is experimental evidence that it has the molecular function</span>: WW domain binding. There is experimental evidence that it is involved in the biological process</span>: neuromuscular synaptic transmission; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived wing vein specification; regulation of short-term neuronal synaptic plasticity; muscle homeostasis; establishment of cell polarity. 40 alleles are reported. The phenotypes of these alleles are annotated with: posterior crossvein; presynaptic active zone; terminal button. It has 8 annotated transcripts and 8 annotated polypeptides.","imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> muscle organ development ; GO:0007517 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> neuromuscular synaptic transmission ; GO:0007274 | inferred from direct assay <newline> regulation of short-term neuronal synaptic plasticity ; GO:0048172 | inferred from direct assay <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype <newline> establishment of cell polarity ; GO:0030010 | inferred from mutant phenotype <newline> muscle cell homeostasis ; GO:0046716 | inferred from mutant phenotype","cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity <newline> dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from sequence or structural similarity with HGNC_gene:DMD; HGNC:2928; OMIM:300377 AND inferred from sequence or structural similarity with HGNC_gene:DRP2; HGNC:3032; OMIM:300052 AND inferred from sequence or structural similarity with HGNC_gene:UTRN; HGNC:12635; OMIM:128240 <newline> dystrophin-associated glycoprotein complex ; GO:0016010 | non-traceable author statement <newline> dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from sequence or structural similarity <newline> cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from physical interaction with Dg","structural molecule activity ; GO:0005198 | inferred from sequence or structural similarity <newline> structural constituent of muscle ; GO:0008307 | inferred from sequence or structural similarity with HGNC_gene:DMD; HGNC:2928; OMIM:300377 AND inferred from sequence or structural similarity with HGNC_gene:DRP2; HGNC:3032; OMIM:300052 AND inferred from sequence or structural similarity with HGNC_gene:UTRN; HGNC:12635; OMIM:128240 <newline> cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity <newline> actin binding ; GO:0003779 | inferred from sequence or structural similarity <newline> actin binding ; GO:0003779 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> structural constituent of muscle ; GO:0008307 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> WW domain binding ; GO:0050699 | inferred from physical interaction with Dg <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433 <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR011992"]
[null,"FBgn0261648","spalt major","salm","The gene spalt major is referred to in FlyBase by the symbol Dmel\\salm (CG6464, FBgn0261648). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:11434311..11445603. It has the cytological map location 32F1-32F2. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity; transcription regulator activity. There is experimental evidence that it is involved in the biological process</span>: oenocyte development; notum cell fate specification; R8 cell differentiation; sensory organ development; compound eye photoreceptor cell differentiation; spiracle morphogenesis, open tracheal system; R7 cell differentiation; open tracheal system development; antennal joint development. 28 alleles are reported. The phenotypes of these alleles are annotated with 52 unique terms, many of which group under: adult segment; adult mesothoracic segment; peripheral nervous system; organ system; nervous system; embryonic/larval tracheal system; embryonic nervous system; antennal segment; appendage segment; embryonic segment. It has one annotated transcript and one annotated polypeptide.","spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> negative regulation of transcription ; GO:0016481 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> oenocyte development ; GO:0007438 | inferred from mutant phenotype <newline> antennal joint development ; GO:0048098 | inferred from mutant phenotype <newline> R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype <newline> R8 cell differentiation ; GO:0045465 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | non-traceable author statement <newline> epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement <newline> R8 cell differentiation ; GO:0045465 | non-traceable author statement <newline> segment specification ; GO:0007379 | non-traceable author statement <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype <newline> notum cell fate specification ; GO:0035310 | inferred from mutant phenotype","nucleus ; GO:0005634 | non-traceable author statement <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> transcription regulator activity ; GO:0030528 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087"]
[null,"FBgn0261885","osa","osa","The gene osa is referred to in FlyBase by the symbol Dmel\\osa (CG7467, FBgn0261885). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:13513540..13544059. It has the cytological map location 90C1-90C2. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; organ development; regulation of biological process; regulation of metabolic process; regionalization; appendage development; positive regulation of cellular biosynthetic process; segment specification; regulation of epidermal growth factor receptor signaling pathway. 62 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: adult segment; adult mesothoracic segment; peripheral nervous system; organ system; nervous system; thoracic segment; dorsal thoracic disc; external compound sense organ; Malpighian tubule; larval thorax; wing cell. It has 4 annotated transcripts and 4 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from mutant phenotype <newline> photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype <newline> segment specification ; GO:0007379 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from direct assay <newline> positive regulation of transcription, DNA-dependent ; GO:0045893 | inferred from direct assay <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> brahma complex ; GO:0035060 | inferred from direct assay <newline> brahma complex ; GO:0035060 | traceable author statement","DNA binding ; GO:0003677 | non-traceable author statement <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> transcription coactivator activity ; GO:0003713 | contributes_to inferred by curator from GO:0035060"]
[null,"FBgn0036666","tumor suppressor protein 101","TSG101","The gene tumor suppressor protein 101 is referred to in FlyBase by the symbol Dmel\\TSG101 (CG9712, FBgn0036666). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:16835399..16837686. It has the cytological map location 73D1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: negative regulation of growth; negative regulation of growth or development of symbiont in host; regulation of JAK-STAT cascade; negative regulation of imaginal disc growth; maintenance of apical/basal cell polarity. 7 alleles are reported. The phenotypes of these alleles are annotated with: yolk granule; oocyte; vesicle. It has one annotated transcript and one annotated polypeptide.","negative regulation of growth ; GO:0045926 | inferred from mutant phenotype <newline> regulation of JAK-STAT cascade ; GO:0046425 | inferred from mutant phenotype <newline> maintenance of apical/basal cell polarity ; GO:0035090 | inferred from mutant phenotype <newline> negative regulation of imaginal disc growth ; GO:0045571 | inferred from mutant phenotype <newline> negative regulation of growth or development of symbiont in host (obsolete GO:0033667) ; GO:0033667 | inferred from mutant phenotype <newline> regulation of protein metabolic process ; GO:0051246 | inferred from electronic annotation with InterPro:IPR000608 <newline> post-translational protein modification ; GO:0043687 | inferred from electronic annotation with InterPro:IPR000608 <newline> protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR008883","-","protein binding ; GO:0005515 | inferred from physical interaction with Vps28 <newline> small conjugating protein ligase activity ; GO:0019787 | inferred from electronic annotation with InterPro:IPR000608"]
[null,"FBgn0035142","homeodomain interacting protein kinase","hipk","The gene homeodomain interacting protein kinase is referred to in FlyBase by the symbol Dmel\\hipk (CG17090, FBgn0035142). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: beta-catenin binding; transcription factor binding; protein serine/threonine kinase activity; protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of Wnt receptor signaling pathway; compound eye development; imaginal disc-derived wing margin morphogenesis; protein stabilization; protein amino acid phosphorylation; imaginal disc-derived wing vein morphogenesis; positive regulation of Notch signaling pathway. 33 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; eye disc; eye; intersegmental nerve; eye photoreceptor cell. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain. Gene sequence location is 3L:543070..576065.","protein phosphorylation ; GO:0006468 | non-traceable author statement <newline> positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with Dl inferred from genetic interaction with N inferred from genetic interaction with gro inferred from genetic interaction with H <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> positive regulation of Wnt receptor signaling pathway ; GO:0030177 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> protein stabilization ; GO:0050821 | inferred from mutant phenotype <newline> protein phosphorylation ; GO:0006468 | inferred from direct assay","-","protein kinase activity ; GO:0004672 | non-traceable author statement <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with SGD_LOCUS:YAK1; SGD:S0003677 <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay <newline> beta-catenin binding ; GO:0008013 | inferred from physical interaction with arm <newline> transcription factor binding ; GO:0008134 | inferred from physical interaction with pan <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0262614","polychaetoid","pyd","The gene polychaetoid is referred to in FlyBase by the symbol Dmel\\pyd (CG43140, FBgn0262614). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: guanylate kinase activity. There is experimental evidence that it is involved in the biological process</span>: bristle development; wing disc development; cell-cell adhesion; fusion cell fate specification; branch fusion, open tracheal system. 66 alleles are reported. The phenotypes of these alleles are annotated with 27 unique terms, many of which group under: peripheral nervous system; organ system; adult segment; external compound sense organ; late extended germ band embryo; non-connected developing functional system; acellular anatomical structure; tracheal branch primordium; integumentary plate; appendage segment. It has 12 annotated transcripts and 12 annotated polypeptides. Protein features are: Guanylate kinase; Guanylate kinase/L-type calcium channel; PDZ/DHR/GLGF; Src homology-3 domain; Variant SH3; ZU5. Gene sequence location is 3R:4653200..4757599.","bristle development ; GO:0022416 | inferred from mutant phenotype <newline> wing disc development ; GO:0035220 | inferred from mutant phenotype <newline> JNK cascade ; GO:0007254 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> dorsal closure ; GO:0007391 | non-traceable author statement <newline> regulation of JNK cascade ; GO:0046328 | non-traceable author statement <newline> establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement <newline> branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype <newline> fusion cell fate specification ; GO:0035156 | inferred from mutant phenotype <newline> cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype","adherens junction ; GO:0005912 | inferred from direct assay <newline> adherens junction ; GO:0005912 | traceable author statement <newline> adherens junction ; GO:0005912 | non-traceable author statement <newline> cell-cell adherens junction ; GO:0005913 | inferred from direct assay","guanylate kinase activity ; GO:0004385 | inferred from sequence or structural similarity with HGNC_gene:TJP1; HGNC:11827; OMIM:601009 AND inferred from sequence or structural similarity with SGD_LOCUS:GUK1; SGD:S0002862 <newline> guanylate kinase activity ; GO:0004385 | non-traceable author statement"]
[null,"FBgn0262582","capicua","cic","The gene capicua is referred to in FlyBase by the symbol Dmel\\cic (CG43122, FBgn0262582). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: wing disc dorsal/ventral pattern formation; eye morphogenesis; imaginal disc-derived wing vein specification; dorsal appendage formation; negative regulation of cell growth. 42 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; anatomical structure; adult segment; thoracic segment; acellular anatomical structure; abdominal segment; adult; egg; larval integumentary system; cell part; external compound sense organ. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Armadillo-like helical; High mobility group, HMG1/HMG2; High mobility group, superfamily. Gene sequence location is 3R:16078492..16128194.","negative regulation of transcription ; GO:0016481 | traceable author statement <newline> embryonic development via the syncytial blastoderm ; GO:0001700 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> eye morphogenesis ; GO:0048592 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> negative regulation of cell growth ; GO:0030308 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:AB014474; protein_id:BAA28604.1 <newline> nucleus ; GO:0005634 | non-traceable author statement","sequence-specific DNA binding transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:AB014474; protein_id:BAA28604.1 <newline> transcription cofactor activity ; GO:0003712 | non-traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription regulator activity ; GO:0030528 | non-traceable author statement <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000910"]
[null,"FBgn0003559","suppressor of forked","su(f)","The gene suppressor of forked is referred to in FlyBase by the symbol Dmel\\su(f) (CG17170, FBgn0003559). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mRNA cleavage. 50 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; adult segment; peripheral nervous system; nervous system; thoracic segment; adult mesothoracic segment; integumentary plate; female germline cyst; external compound sense organ; prothoracic leg; adult. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: RNA-processing protein, HAT helix; Suppressor of forked. Gene sequence location is XHet:69195..80010.","mRNA cleavage ; GO:0006379 | inferred from sequence or structural similarity with NCBI_NP:001317 <newline> mRNA cleavage ; GO:0006379 | inferred from sequence or structural similarity <newline> mRNA cleavage ; GO:0006379 | inferred from sequence or structural similarity with NCBI_gi:4557495 <newline> RNA metabolic process ; GO:0016070 | non-traceable author statement","mRNA cleavage stimulating factor complex ; GO:0005848 | inferred from sequence or structural similarity with NCBI_NP:001317 <newline> mRNA cleavage stimulating factor complex ; GO:0005848 | inferred from sequence or structural similarity <newline> mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from sequence or structural similarity with NCBI_gi:4557495 <newline> nucleus ; GO:0005634 | non-traceable author statement","-"]
[null,"FBgn0087007","big bang","bbg","The gene big bang is referred to in FlyBase by the symbol Dmel\\bbg (CG42230, FBgn0087007). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: imaginal disc development. 39 alleles are reported. The phenotype of these alleles is annotated with: imaginal disc. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: PDZ/DHR/GLGF. Gene sequence location is 3L:14405921..14506348.","imaginal disc development ; GO:0007444 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay","-"]
[null,"FBgn0010575","scribbler","sbb","The gene scribbler is referred to in FlyBase by the symbol Dmel\\sbb (CG5580, FBgn0010575). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: transcription corepressor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of gene-specific transcription from RNA polymerase II promoter; axon guidance; wing disc dorsal/ventral pattern formation; imaginal disc-derived wing morphogenesis; axon target recognition; regulation of imaginal disc growth; negative regulation of smoothened signaling pathway; larval locomotory behavior. 93 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: peripheral nervous system; adult segment; organ system; nervous system; integumentary plate; thoracic segment; multi-cell-component structure; adult mesothoracic segment; synaptic neuropil subdomain; dorsal thoracic disc. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Zinc finger, C2H2-like; Zinc finger, C2H2-type. Gene sequence location is 2R:14166570..14244766.","axon target recognition ; GO:0007412 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | non-traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement <newline> photoreceptor cell development ; GO:0042461 | non-traceable author statement <newline> larval locomotory behavior ; GO:0008345 | traceable author statement <newline> regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> negative regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010553 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","sequence-specific DNA binding transcription factor activity ; GO:0003700 | non-traceable author statement <newline> transcription corepressor activity ; GO:0003714 | inferred from direct assay <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0040066","will die slowly","wds","The gene will die slowly is referred to in FlyBase by the symbol Dmel\\wds (CG17437, FBgn0040066). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 53 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; wing vein L3; female reproductive system; posterior vertical bristle; ovary; macrochaeta; wing; wing vein; wing vein L2; posterior scutellar bristle. It has one annotated transcript and one annotated polypeptide. Protein features are: G-protein beta WD-40 repeat; WD40 repeat; WD40 repeat 2; WD40 repeat, conserved site; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Gene sequence location is X:2480010..2481926.","-","microtubule associated complex ; GO:0005875 | inferred from direct assay","-"]
[null,"FBgn0003741","transformer","tra","The gene transformer is referred to in FlyBase by the symbol Dmel\\tra (CG16724, FBgn0003741). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: male courtship behavior, veined wing generated song production; inter-male aggressive behavior; male courtship behavior, veined wing extension; male courtship behavior. 59 alleles are reported. The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; cytoplasmic part; adult segment; larval abdominal segment; nervous system; imaginal precursor; hub cell; spermatocyte; spermatozoon; female germline cyst; primordium; female genitalia. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Fruit fly transformer. Gene sequence location is 3L:16583032..16584413.","female somatic sex determination ; GO:0019101 | traceable author statement <newline> nuclear mRNA splicing, via spliceosome ; GO:0000398 | non-traceable author statement <newline> sex determination, primary response to X:A ratio ; GO:0007541 | non-traceable author statement <newline> somatic sex determination ; GO:0018993 | non-traceable author statement <newline> spliceosome assembly ; GO:0000245 | non-traceable author statement <newline> sex determination ; GO:0007530 | non-traceable author statement <newline> RNA splicing ; GO:0008380 | traceable author statement <newline> sex differentiation ; GO:0007548 | traceable author statement <newline> female sex determination ; GO:0030237 | non-traceable author statement <newline> nuclear mRNA splicing, via spliceosome ; GO:0000398 | traceable author statement <newline> sex determination ; GO:0007530 | traceable author statement <newline> male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype <newline> male courtship behavior, veined wing extension ; GO:0048065 | inferred from mutant phenotype <newline> male courtship behavior ; GO:0008049 | inferred from mutant phenotype <newline> negative regulation of translation ; GO:0017148 | non-traceable author statement <newline> male courtship behavior ; GO:0008049 | inferred from direct assay <newline> inter-male aggressive behavior ; GO:0002121 | inferred from direct assay <newline> female sex differentiation ; GO:0046660 | inferred from electronic annotation with InterPro:IPR010519 <newline> mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR010519","spliceosomal complex ; GO:0005681 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR010519","-"]
[null,"FBgn0004603","Src oncogene at 42A","Src42A","The gene Src oncogene at 42A is referred to in FlyBase by the symbol Dmel\\Src42A (CG7873, FBgn0004603). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: protein tyrosine kinase activity. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; macromolecule modification; localization; protein modification process; organ morphogenesis; post-embryonic organ morphogenesis; organ development; gland morphogenesis; biological regulation; cellular macromolecule metabolic process; signaling pathway; catabolic process; actin filament-based process. 55 alleles are reported. The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: organ system; adult segment; nervous system; cuticle; adult mesothoracic segment; external compound sense organ; peripheral nervous system; embryonic/larval tracheal system; embryonic nervous system; taenidial fold; female germline cyst; rhabdomere; egg; embryonic segment; cephalopharyngeal skeleton; late extended germ band embryo. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; SH2 motif; Serine-threonine/tyrosine-protein kinase; Src homology-3 domain; Tyrosine-protein kinase; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, non-receptor FRK. Gene sequence location is 2R:1868785..1900039.","cell communication ; GO:0007154 | inferred from direct assay <newline> negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with Ras85D <newline> transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from genetic interaction with phl <newline> dorsal closure ; GO:0007391 | inferred from genetic interaction with Src64B AND inferred from genetic interaction with bsk AND inferred from genetic interaction with hep AND inferred from mutant phenotype <newline> protein phosphorylation ; GO:0006468 | non-traceable author statement <newline> peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from mutant phenotype <newline> protein phosphorylation ; GO:0006468 | inferred from direct assay AND inferred from mutant phenotype <newline> dorsal closure, spreading of leading edge cells ; GO:0007395 | inferred from mutant phenotype <newline> imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype <newline> JNK cascade ; GO:0007254 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from genetic interaction with Fps85D inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype <newline> apoptotic cell clearance ; GO:0043277 | inferred from mutant phenotype <newline> tricarboxylic acid cycle ; GO:0006099 | inferred from direct assay","adherens junction ; GO:0005912 | inferred from direct assay <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR020702","non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from sequence or structural similarity <newline> protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity <newline> protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement <newline> protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441, InterPro:IPR020702 <newline> non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from electronic annotation with InterPro:IPR020702"]
[null,"FBgn0001942","Eukaryotic initiation factor 4a","eIF-4a","The gene Eukaryotic initiation factor 4a is referred to in FlyBase by the symbol Dmel\\eIF-4a (CG9075, FBgn0001942). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: translation initiation factor activity; RNA helicase activity. There is experimental evidence that it is involved in the biological process</span>: germ-line stem cell maintenance; mitotic spindle elongation; response to DNA damage stimulus; mitosis; mitotic spindle organization; dorsal/ventral axis specification; oogenesis; female germ-line stem cell division; regulation of alternative nuclear mRNA splicing, via spliceosome. 66 alleles are reported. The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: anatomical structure; developing anatomical structure; organ system; cuticle; peripheral nervous system; nervous system; parasegment 9; dorsal thoracic disc; multi-cell-component structure; parasegment 14; parasegment 2; cephalopharyngeal skeleton; external compound sense organ; late extended germ band embryo. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: DEAD-like helicase, N-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Helicase, superfamily 1/2, ATP-binding domain; RNA helicase, ATP-dependent, DEAD-box, conserved site; RNA helicase, DEAD-box type, Q motif. Gene sequence location is 2L:5981759..5985572.","dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype <newline> translational initiation ; GO:0006413 | inferred from sequence or structural similarity with SGD_LOCUS:TIF1; SGD:S0001767 <newline> translational initiation ; GO:0006413 | non-traceable author statement <newline> imaginal disc growth ; GO:0007446 | traceable author statement <newline> instar larval development ; GO:0002168 | traceable author statement <newline> translational initiation ; GO:0006413 | inferred from sequence or structural similarity <newline> DNA unwinding involved in replication ; GO:0006268 | non-traceable author statement <newline> regulation of alternative nuclear mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype <newline> mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from genetic interaction with bam <newline> female germ-line stem cell division ; GO:0048132 | inferred from genetic interaction with bam inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype <newline> mitosis ; GO:0007067 | inferred from mutant phenotype","eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity with SGD_LOCUS:TIF1; SGD:S0001767 <newline> cytosol ; GO:0005829 | non-traceable author statement <newline> cytosol ; GO:0005829 | inferred from sequence or structural similarity <newline> eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity <newline> nucleus ; GO:0005634 | inferred by curator from GO:0000381 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity <newline> translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD_LOCUS:TIF1; SGD:S0001767 <newline> translation initiation factor activity ; GO:0003743 | non-traceable author statement <newline> RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity with SGD_LOCUS:TIF2; SGD:S0003674 <newline> translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity <newline> RNA cap binding ; GO:0000339 | non-traceable author statement <newline> mRNA binding ; GO:0003729 | non-traceable author statement <newline> single-stranded DNA-dependent ATP-dependent DNA helicase activity ; GO:0017116 | non-traceable author statement <newline> ATP-dependent helicase activity ; GO:0008026 | inferred from electronic annotation with InterPro:IPR000629, InterPro:IPR011545 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000629, InterPro:IPR001650, InterPro:IPR011545"]
[null,"FBgn0003277","RNA polymerase II 215kD subunit","RpII215","The gene RNA polymerase II 215kD subunit is referred to in FlyBase by the symbol Dmel\\RpII215 (CG1554, FBgn0003277). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: DNA-directed RNA polymerase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transcription from RNA polymerase II promoter. 173 alleles are reported. The phenotypes of these alleles are annotated with: haltere; capitellum. It has one annotated transcript and one annotated polypeptide. Protein features are: RNA polymerase II, heptapeptide repeat, eukaryotic; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 5; RNA polymerase Rpb1, domain 6; RNA polymerase Rpb1, domain 7; RNA polymerase, N-terminal; RNA polymerase, alpha subunit. Gene sequence location is X:11456806..11464355.","transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with HGNC_gene:POLR2A; HGNC:9187; OMIM:180660 AND inferred from sequence or structural similarity with SGD_LOCUS:RPO21; SGD:S0002299 AND inferred from sequence or structural similarity with WB:ama-1; WP:CE28300 <newline> transcription from RNA polymerase II promoter ; GO:0006366 | non-traceable author statement","DNA-directed RNA polymerase II, core complex ; GO:0005665 | inferred from sequence or structural similarity with HGNC_gene:POLR2A; HGNC:9187; OMIM:180660 AND inferred from sequence or structural similarity with SGD_LOCUS:RPO21; SGD:S0002299 AND inferred from sequence or structural similarity with WB:ama-1; WP:CE28300 <newline> DNA-directed RNA polymerase II, core complex ; GO:0005665 | non-traceable author statement <newline> polytene chromosome puff ; GO:0005703 | inferred from direct assay","DNA-directed RNA polymerase activity ; GO:0003899 | inferred from sequence or structural similarity with HGNC_gene:POLR2A; HGNC:9187; OMIM:180660 AND inferred from sequence or structural similarity with SGD_LOCUS:RPO21; SGD:S0002299 AND inferred from sequence or structural similarity with WB:ama-1; WP:CE28300 <newline> DNA-directed RNA polymerase activity ; GO:0003899 | non-traceable author statement <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000684, InterPro:IPR000722, InterPro:IPR006592, InterPro:IPR007066, InterPro:IPR007073, InterPro:IPR007075, InterPro:IPR007080, InterPro:IPR007081, InterPro:IPR007083"]
[null,"FBgn0261618","La related protein","larp","The gene La related protein is referred to in FlyBase by the symbol Dmel\\larp (CG42551, FBgn0261618). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: mitochondrion inheritance; mitotic chromosome condensation; centrosome separation; spindle assembly involved in male meiosis; syncytial blastoderm mitotic cell cycle; male meiosis; spindle assembly; autophagic cell death; salivary gland cell autophagic cell death. 35 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; organelle; peripheral nervous system; cytoplasmic part; anatomical structure; nucleus; nuclear part; cell cycle; external compound sense organ; male organism; sense organ. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Protein of unknown function DM15; RNA-binding protein Lupus La; Winged helix-turn-helix transcription repressor DNA-binding. Gene sequence location is 3R:24143905..24162162.","centrosome separation ; GO:0051299 | inferred from mutant phenotype <newline> mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> spindle assembly ; GO:0051225 | inferred from mutant phenotype <newline> mitochondrion inheritance ; GO:0000001 | inferred from mutant phenotype <newline> male meiosis ; GO:0007140 | inferred from mutant phenotype <newline> spindle assembly involved in male meiosis ; GO:0007053 | inferred from mutant phenotype <newline> syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay <newline> cytosol ; GO:0005829 | inferred from direct assay <newline> mitochondrion ; GO:0005739 | colocalizes_with inferred from direct assay","molecular_function ; GO:0003674 | no biological data available"]
[null,"FBgn0004655","wings apart-like","wapl","The gene wings apart-like is referred to in FlyBase by the symbol Dmel\\wapl (CG3707, FBgn0004655). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. There is experimental evidence that it is involved in the biological process</span>: female meiosis chromosome segregation; sister chromatid cohesion. 37 alleles are reported. The phenotypes of these alleles are annotated with: eye; wing; tergite; wing vein. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Armadillo-like helical; Armadillo-type fold; Wings apart-like protein; Wings apart-like, metazoan/plants. Gene sequence location is X:2044135..2053016.","sister chromatid cohesion ; GO:0007062 | inferred from mutant phenotype <newline> female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype","cellular_component ; GO:0005575 | no biological data available","binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR011989, InterPro:IPR016024"]
[null,"FBgn0000352","costa","cos","The gene costa is referred to in FlyBase by the symbol Dmel\\cos (CG1708, FBgn0000352). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: smoothened binding; microtubule binding; protein binding; protein kinase binding; transcription factor binding. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; regulation of protein stability; negative regulation of transcription factor activity; imaginal disc-derived wing morphogenesis; cytoplasmic sequestering of transcription factor; negative regulation of transcription factor import into nucleus; positive regulation of hh target transcription factor activity. 88 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; thoracic segment; imaginal precursor; adult; dorsal thoracic disc; abdominal segment 10; vulva; epiproct. It has one annotated transcript and one annotated polypeptide. Protein features are: Kinesin, motor domain. Gene sequence location is 2R:3269669..3274617.","ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> positive regulation of hh target transcription factor activity ; GO:0007228 | inferred from mutant phenotype <newline> negative regulation of transcription factor import into nucleus ; GO:0042992 | inferred from mutant phenotype <newline> microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity <newline> regulation of proteolysis ; GO:0030162 | non-traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | inferred from physical interaction with smo <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | traceable author statement <newline> positive regulation of smoothened signaling pathway ; GO:0045880 | traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> regulation of protein stability ; GO:0031647 | inferred from direct assay <newline> negative regulation of transcription factor activity ; GO:0043433 | inferred from mutant phenotype <newline> cytoplasmic sequestering of transcription factor ; GO:0042994 | inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype <newline> microtubule-based movement ; GO:0007018 | inferred from electronic annotation with InterPro:IPR001752","cytoplasm ; GO:0005737 | inferred from direct assay <newline> kinesin complex ; GO:0005871 | inferred from sequence or structural similarity with Khc <newline> microtubule associated complex ; GO:0005875 | inferred from physical interaction with ci <newline> kinesin complex ; GO:0005871 | inferred from sequence or structural similarity with SGD_LOCUS:KIP3; SGD:S000003184 <newline> Hedgehog signaling complex ; GO:0035301 | inferred from physical interaction with ci AND inferred from physical interaction with fu <newline> kinesin complex ; GO:0005871 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> vesicle membrane ; GO:0012506 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | traceable author statement","microtubule binding ; GO:0008017 | inferred from direct assay <newline> motor activity ; GO:0003774 | inferred from sequence or structural similarity with Khc <newline> microtubule motor activity ; GO:0003777 | inferred from sequence or structural similarity <newline> smoothened binding ; GO:0005119 | inferred from physical interaction with smo <newline> protein binding ; GO:0005515 | inferred from physical interaction with fu <newline> protein kinase binding ; GO:0019901 | inferred from physical interaction with fu <newline> transcription factor binding ; GO:0008134 | inferred from physical interaction with ci <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001752 <newline> microtubule motor activity ; GO:0003777 | inferred from electronic annotation with InterPro:IPR001752"]
[]
["Notum development"]
[null,"FBgn0000625","eyegone","eyg","The gene eyegone is referred to in FlyBase by the symbol Dmel\\eyg (CG10488, FBgn0000625). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:12456132..12461121. It has the cytological map location 69C2. There is experimental evidence that it has the molecular function</span>: transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: notum development; eye development; antennal development; eye-antennal disc development; compound eye development; compound eye morphogenesis. 54 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: adult segment; adult mesothoracic segment; peripheral nervous system; nervous system; organ system; imaginal precursor; external compound sense organ; integumentary plate; salivary gland imaginal ring; dorsal thoracic disc. It has 2 annotated transcripts and 2 annotated polypeptides.","eye development ; GO:0001654 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> antennal development ; GO:0007469 | inferred from mutant phenotype <newline> notum development ; GO:0007477 | inferred from mutant phenotype <newline> eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970","transcription factor complex ; GO:0005667 | inferred from sequence or structural similarity with MGD:Pax3; MGI:MGI:97487","transcription repressor activity ; GO:0016564 | inferred from mutant phenotype <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with MGD:Pax3; MGI:MGI:97487 <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970"]
[null,"FBgn0001235","homothorax","hth","The gene homothorax is referred to in FlyBase by the symbol Dmel\\hth (CG17117, FBgn0001235). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:6335569..6464386. It has the cytological map location 86C1-86C3. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of gene-specific transcription from RNA polymerase II promoter; compound eye development; specification of segmental identity, antennal segment; specification of segmental identity, head; segmentation; compound eye photoreceptor fate commitment; brain development; imaginal disc-derived wing morphogenesis; haltere morphogenesis; imaginal disc-derived leg morphogenesis. 64 alleles are reported. The phenotypes of these alleles are annotated with 63 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; thoracic segment; external compound sense organ; appendage segment; adult mesothoracic segment; embryonic segment; embryonic nervous system; organ system; antennal segment. It has 8 annotated transcripts and 8 annotated polypeptides.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> brain development ; GO:0007420 | inferred from mutant phenotype <newline> proximal/distal pattern formation ; GO:0009954 | traceable author statement <newline> specification of organ identity ; GO:0010092 | traceable author statement <newline> compound eye photoreceptor fate commitment ; GO:0001752 | inferred from mutant phenotype <newline> leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype <newline> specification of segmental identity, antennal segment ; GO:0007383 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype <newline> haltere morphogenesis ; GO:0048735 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> transcription factor activity ; GO:0003700 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356"]
[null,"FBgn0000117","armadillo","arm","The gene armadillo is referred to in FlyBase by the symbol Dmel\\arm (CG11579, FBgn0000117). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1785434..1794673. It has the cytological map location 2B14. There is experimental evidence that it has the molecular function</span>: transcription activator activity; protein binding; transcription coactivator activity. There is experimental evidence for 22 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; cell adhesion; positive regulation of cellular biosynthetic process; regulation of developmental process; sensory organ development; positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; stem cell differentiation; reproductive process in a multicellular organism; delamination; cell junction organization. 177 alleles are reported. The phenotypes of these alleles are annotated with 100 unique terms, many of which group under: organ system; adult segment; abdominal ventral denticle belt; embryonic nervous system; female germline cyst; adult mesothoracic segment; embryonic/larval tracheal system; embryonic neuron; external compound sense organ; peripheral nervous system. It has 5 annotated transcripts and 5 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from sequence or structural similarity with MGD:Catnb; MGI:MGI:88276 <newline> cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | non-traceable author statement <newline> neuroblast fate determination ; GO:0007400 | non-traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> oocyte localization during germarium-derived egg chamber formation ; GO:0030720 | traceable author statement <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> heart development ; GO:0007507 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> positive regulation of JNK cascade ; GO:0046330 | traceable author statement <newline> protein localization ; GO:0008104 | traceable author statement <newline> germ-line stem cell division ; GO:0042078 | non-traceable author statement <newline> zonula adherens assembly ; GO:0045186 | traceable author statement <newline> establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement <newline> somatic stem cell maintenance ; GO:0035019 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype <newline> zonula adherens assembly ; GO:0045186 | inferred from mutant phenotype <newline> cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype <newline> cell morphogenesis ; GO:0000902 | inferred from mutant phenotype <newline> ventral furrow formation ; GO:0007370 | inferred from mutant phenotype <newline> neuroblast development ; GO:0014019 | inferred from mutant phenotype <newline> photoreceptor cell differentiation ; GO:0046530 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> compound eye retinal cell programmed cell death ; GO:0046667 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from direct assay <newline> imaginal disc-derived wing expansion ; GO:0048526 | inferred from mutant phenotype <newline> delamination ; GO:0060232 | inferred from mutant phenotype <newline> wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | inferred from mutant phenotype <newline> positive regulation of transcription ; GO:0045941 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | inferred from mutant phenotype","zonula adherens ; GO:0005915 | inferred from direct assay <newline> catenin complex ; GO:0016342 | inferred from sequence or structural similarity <newline> adherens junction ; GO:0005912 | non-traceable author statement <newline> catenin complex ; GO:0016342 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | non-traceable author statement <newline> membrane ; GO:0016020 | non-traceable author statement <newline> apicolateral plasma membrane ; GO:0016327 | traceable author statement <newline> adherens junction ; GO:0005912 | inferred from direct assay <newline> adherens junction ; GO:0005912 | traceable author statement <newline> cytoplasm ; GO:0005737 | traceable author statement <newline> spot adherens junction ; GO:0005914 | non-traceable author statement <newline> zonula adherens ; GO:0005915 | non-traceable author statement <newline> zonula adherens ; GO:0005915 | traceable author statement <newline> apical plasma membrane ; GO:0016324 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from physical interaction with pygo <newline> cytoplasm ; GO:0005737 | inferred from direct assay","cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity <newline> protein binding ; GO:0005515 | inferred from physical interaction with Apc2 AND inferred from physical interaction with Mer <newline> alpha-catenin binding ; GO:0045294 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P22265 <newline> transcription activator activity ; GO:0016563 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with Apc2 <newline> transcription coactivator activity ; GO:0003713 | inferred from direct assay"]
[null,"FBgn0003016","outspread","osp","The gene outspread is referred to in FlyBase by the symbol Dmel\\osp (CG3479, FBgn0003016). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:14599776..14689325. It has the cytological map location 35B3-35B4. Its molecular function is unknown. The biological processes in which it is involved are not known. 53 alleles are reported. The phenotypes of these alleles are annotated with: wing; thorax; crystal cell. It has 4 annotated transcripts and 4 annotated polypeptides.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
[null,"FBgn0003371","shaggy","sgg","The gene shaggy is referred to in FlyBase by the symbol Dmel\\sgg (CG2621, FBgn0003371). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2527983..2571879. It has the cytological map location 3A8-3B1. There is experimental evidence that it has the molecular function</span>: protein kinase activity; kinase activity. There is experimental evidence for 16 unique biological process</span> terms, many of which group under: anatomical structure development; regulation of biological process; reproductive process in a multicellular organism; organ development; learning; regulation of circadian rhythm; multicellular organism reproduction; learning or memory; regionalization; biopolymer modification; circadian rhythm; regulation of developmental process; embryonic pattern specification; olfactory learning; entrainment of circadian clock; regulation of metabolic process. 149 alleles are reported. The phenotypes of these alleles are annotated with 44 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; abdominal ventral denticle belt; nervous system; external compound sense organ; cuticle; larval abdominal segment; embryonic/larval hemocoel. It has 15 annotated transcripts and 15 annotated polypeptides.","synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> circadian rhythm ; GO:0007623 | inferred from mutant phenotype <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype <newline> heart development ; GO:0007507 | non-traceable author statement <newline> protein localization ; GO:0008104 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> negative regulation of Wnt receptor signaling pathway ; GO:0030178 | traceable author statement <newline> blastoderm segmentation ; GO:0007350 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> bristle morphogenesis ; GO:0008407 | non-traceable author statement <newline> circadian rhythm ; GO:0007623 | non-traceable author statement <newline> locomotor rhythm ; GO:0045475 | non-traceable author statement <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from direct assay <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay <newline> regulation of proteolysis ; GO:0030162 | inferred from direct assay <newline> circadian rhythm ; GO:0007623 | traceable author statement <newline> Notch signaling pathway ; GO:0007219 | traceable author statement <newline> regulation of protein import into nucleus ; GO:0042306 | traceable author statement <newline> rhythmic behavior ; GO:0007622 | traceable author statement <newline> regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype <newline> entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype <newline> wing and notum subfield formation ; GO:0035309 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> olfactory learning ; GO:0008355 | inferred from mutant phenotype <newline> habituation ; GO:0046959 | inferred from mutant phenotype <newline> regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype","-","protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity <newline> protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement <newline> kinase activity ; GO:0016301 | inferred from direct assay <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> glycogen synthase kinase 3 activity ; GO:0004696 | non-traceable author statement <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017442 <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR002290, InterPro:IPR008271"]
[null,"FBgn0004644","hedgehog","hh","The gene hedgehog is referred to in FlyBase by the symbol Dmel\\hh (CG4637, FBgn0004644). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:18953425..18967881. It has the cytological map location 94E1. There is experimental evidence that it has the molecular function</span>: cell surface binding; protein binding. There is experimental evidence for 24 unique biological process</span> terms, many of which group under: anatomical structure development; cellular component movement; organ morphogenesis; regulation of biological process; sensory organ development; reproductive process in a multicellular organism; organ development; regulation of protein transport; cell projection organization; open tracheal system development; central nervous system development. 170 alleles are reported. The phenotypes of these alleles are annotated with 190 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; primordium; nervous system; late extended germ band embryo; ventral nerve cord primordium; embryonic nervous system; abdominal ventral denticle belt. It has 2 annotated transcripts and 2 annotated polypeptides.","pole cell migration ; GO:0007280 | inferred from genetic interaction with Hmgcr inferred from genetic interaction with disp <newline> progression of morphogenetic furrow during compound eye morphogenesis ; GO:0007458 | inferred from expression pattern AND inferred from genetic interaction with dpp AND inferred from genetic interaction with h AND inferred from genetic interaction with sca AND inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo <newline> germ cell migration ; GO:0008354 | inferred from mutant phenotype <newline> gonadal mesoderm development ; GO:0007506 | inferred from mutant phenotype <newline> positive regulation of hh target transcription factor activity ; GO:0007228 | inferred from genetic interaction with Su(fu) AND inferred from genetic interaction with fu <newline> Bolwig's organ morphogenesis ; GO:0001746 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | traceable author statement <newline> hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype <newline> regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype <newline> epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype <newline> glial cell migration ; GO:0008347 | inferred from mutant phenotype <newline> labial disc development ; GO:0035217 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> morphogenesis of larval imaginal disc epithelium ; GO:0016335 | inferred from mutant phenotype <newline> protein autoprocessing ; GO:0016540 | inferred from direct assay AND inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | traceable author statement <newline> positive regulation of smoothened signaling pathway ; GO:0045880 | traceable author statement <newline> protein autoprocessing ; GO:0016540 | traceable author statement <newline> protein splicing ; GO:0030908 | traceable author statement <newline> cytoneme assembly ; GO:0035231 | inferred from mutant phenotype <newline> foregut morphogenesis ; GO:0007440 | traceable author statement <newline> hindgut morphogenesis ; GO:0007442 | traceable author statement <newline> anterior/posterior lineage restriction, imaginal disc ; GO:0048099 | traceable author statement <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | traceable author statement <newline> imaginal disc-derived wing vein specification ; GO:0007474 | traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> ovarian follicle cell stalk formation ; GO:0030713 | traceable author statement <newline> epidermis development ; GO:0008544 | traceable author statement <newline> growth ; GO:0040007 | non-traceable author statement <newline> germ-line stem cell division ; GO:0042078 | traceable author statement <newline> ectoderm development ; GO:0007398 | non-traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> mesoderm development ; GO:0007498 | non-traceable author statement <newline> imaginal disc pattern formation ; GO:0007447 | non-traceable author statement <newline> regulation of organ growth ; GO:0046620 | traceable author statement <newline> analia development ; GO:0007487 | traceable author statement <newline> genital disc development ; GO:0035215 | traceable author statement <newline> leg disc morphogenesis ; GO:0007478 | traceable author statement <newline> regulation of cell proliferation ; GO:0042127 | non-traceable author statement <newline> compartment pattern formation ; GO:0007386 | traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | non-traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | traceable author statement <newline> segment polarity determination ; GO:0007367 | non-traceable author statement <newline> anterior/posterior axis specification, embryo ; GO:0008595 | non-traceable author statement <newline> R8 cell fate specification ; GO:0045464 | non-traceable author statement <newline> heart development ; GO:0007507 | non-traceable author statement <newline> progression of morphogenetic furrow during compound eye morphogenesis ; GO:0007458 | traceable author statement <newline> somatic stem cell division ; GO:0048103 | traceable author statement <newline> protein autoprocessing ; GO:0016540 | non-traceable author statement <newline> wing disc proximal/distal pattern formation ; GO:0007473 | traceable author statement <newline> germ cell attraction ; GO:0035232 | traceable author statement <newline> developmental pigmentation ; GO:0048066 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> regulation of protein import into nucleus ; GO:0042306 | inferred from mutant phenotype <newline> imaginal disc growth ; GO:0007446 | traceable author statement <newline> anterior head segmentation ; GO:0035288 | traceable author statement <newline> posterior head segmentation ; GO:0035289 | traceable author statement <newline> segment polarity determination ; GO:0007367 | traceable author statement <newline> trunk segmentation ; GO:0035290 | traceable author statement <newline> genital disc development ; GO:0035215 | inferred from mutant phenotype <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | traceable author statement <newline> genital disc anterior/posterior pattern formation ; GO:0035224 | inferred from expression pattern <newline> eye morphogenesis ; GO:0048592 | inferred from mutant phenotype <newline> ventral midline development ; GO:0007418 | inferred from mutant phenotype <newline> anterior commissure morphogenesis ; GO:0021960 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from expression pattern <newline> positive regulation of transcription factor import into nucleus ; GO:0042993 | inferred from mutant phenotype <newline> cell-cell signaling ; GO:0007267 | inferred from electronic annotation with InterPro:IPR000320 <newline> proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001767 <newline> intein-mediated protein splicing ; GO:0016539 | inferred from electronic annotation with InterPro:IPR006141","extracellular region ; GO:0005576 | traceable author statement <newline> cytoplasmic membrane-bounded vesicle ; GO:0016023 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | non-traceable author statement <newline> extracellular region ; GO:0005576 | non-traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> endocytic vesicle ; GO:0030139 | inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with iHog <newline> cell surface binding ; GO:0043498 | inferred from direct assay <newline> patched binding ; GO:0005113 | traceable author statement <newline> cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity <newline> signal transducer activity ; GO:0004871 | traceable author statement <newline> morphogen activity ; GO:0016015 | traceable author statement <newline> endopeptidase activity ; GO:0004175 | non-traceable author statement <newline> patched binding ; GO:0005113 | non-traceable author statement <newline> peptidase activity ; GO:0008233 | inferred from electronic annotation with InterPro:IPR001767"]
[null,"FBgn0004647","Notch","N","The gene Notch is referred to in FlyBase by the symbol Dmel\\N (CG3936, FBgn0004647). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3028905..3066295. It has the cytological map location 3C7-3C9. There is experimental evidence that it has the molecular function</span>: protein binding; specific transcriptional repressor activity; transcription activator activity. There is experimental evidence for 54 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; organ development; regulation of developmental process; sensory organ development; organ morphogenesis; regulation of neurogenesis; cellular component movement; ovarian follicle cell development; regulation of biological process. 653 alleles are reported. The phenotypes of these alleles are annotated with 219 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; adult mesothoracic segment; organ system; external compound sense organ; embryonic nervous system; multi-cell-component structure; primordium; embryonic neuron. It has one annotated transcript and one annotated polypeptide.","stem cell differentiation ; GO:0048863 | inferred from mutant phenotype <newline> regulation of neurogenesis ; GO:0050767 | inferred from mutant phenotype <newline> ectoderm development ; GO:0007398 | traceable author statement <newline> mesoderm development ; GO:0007498 | inferred from mutant phenotype <newline> ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> leg joint morphogenesis ; GO:0035111 | inferred from mutant phenotype <newline> leg segmentation ; GO:0035286 | inferred from mutant phenotype <newline> R8 cell development ; GO:0045463 | traceable author statement <newline> cell adhesion ; GO:0007155 | traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> glial cell fate determination ; GO:0007403 | inferred from mutant phenotype <newline> peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype <newline> germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> muscle cell fate determination ; GO:0007521 | inferred from mutant phenotype <newline> regulation of cardioblast cell fate specification ; GO:0042686 | inferred from mutant phenotype <newline> regulation of growth ; GO:0040008 | inferred from genetic interaction with scrib AND inferred from mutant phenotype <newline> foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype <newline> oocyte localization during germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> anesthesia-resistant memory ; GO:0007615 | NOT inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from mutant phenotype <newline> lateral inhibition ; GO:0046331 | traceable author statement <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype <newline> cell fate specification ; GO:0001708 | traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> anterior/posterior pattern formation ; GO:0009952 | traceable author statement <newline> leg disc morphogenesis ; GO:0007478 | traceable author statement <newline> cell fate commitment ; GO:0045165 | non-traceable author statement <newline> negative regulation of fusion cell fate specification ; GO:0035157 | traceable author statement <newline> negative regulation of terminal cell fate specification, open tracheal system ; GO:0035155 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> imaginal disc growth ; GO:0007446 | traceable author statement <newline> imaginal disc pattern formation ; GO:0007447 | traceable author statement <newline> skeletal muscle tissue development ; GO:0007519 | inferred from mutant phenotype <newline> ovarian follicle cell stalk formation ; GO:0030713 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> germarium-derived egg chamber formation ; GO:0007293 | traceable author statement <newline> germarium-derived female germ-line cyst encapsulation ; GO:0030708 | traceable author statement <newline> morphogenesis of follicular epithelium ; GO:0016333 | non-traceable author statement <newline> oocyte anterior/posterior axis specification ; GO:0007314 | traceable author statement <newline> dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | traceable author statement <newline> establishment of ommatidial planar polarity ; GO:0042067 | non-traceable author statement <newline> cell fate specification ; GO:0001708 | non-traceable author statement <newline> compound eye retinal cell programmed cell death ; GO:0046667 | traceable author statement <newline> second mitotic wave during compound eye morphogenesis ; GO:0016330 | non-traceable author statement <newline> R8 cell differentiation ; GO:0045465 | non-traceable author statement <newline> regulation of R8 cell spacing in compound eye ; GO:0045468 | non-traceable author statement <newline> dorsal/ventral pattern formation, imaginal disc ; GO:0007450 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> lateral inhibition ; GO:0046331 | non-traceable author statement <newline> negative regulation of JNK cascade ; GO:0046329 | non-traceable author statement <newline> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | NOT non-traceable author statement <newline> establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement <newline> crystal cell differentiation ; GO:0042688 | inferred from mutant phenotype <newline> embryonic hemopoiesis ; GO:0035162 | inferred from mutant phenotype <newline> hemocyte proliferation ; GO:0035172 | inferred from mutant phenotype <newline> larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype <newline> R3/R4 cell fate commitment ; GO:0007464 | non-traceable author statement <newline> retinal cell programmed cell death ; GO:0046666 | traceable author statement <newline> wing disc proximal/distal pattern formation ; GO:0007473 | traceable author statement <newline> regulation of crystal cell differentiation ; GO:0042689 | traceable author statement <newline> asymmetric cell division ; GO:0008356 | traceable author statement <newline> ventral cord development ; GO:0007419 | non-traceable author statement <newline> R7 cell differentiation ; GO:0045466 | traceable author statement <newline> regulation of mitotic cell cycle ; GO:0007346 | traceable author statement <newline> lymph gland crystal cell differentiation ; GO:0035170 | traceable author statement <newline> embryonic crystal cell differentiation ; GO:0035165 | traceable author statement <newline> long-term memory ; GO:0007616 | traceable author statement <newline> lymph gland development ; GO:0048542 | inferred from mutant phenotype <newline> negative regulation of compound eye photoreceptor development ; GO:0045316 | inferred from mutant phenotype <newline> positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> compound eye cone cell fate commitment ; GO:0042676 | traceable author statement <newline> compound eye development ; GO:0048749 | non-traceable author statement <newline> compound eye development ; GO:0048749 | traceable author statement <newline> R8 cell fate commitment ; GO:0007460 | traceable author statement <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> heterophilic cell-cell adhesion ; GO:0007157 | inferred from mutant phenotype inferred from direct assay <newline> positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype <newline> lamellocyte differentiation ; GO:0035171 | inferred from mutant phenotype <newline> response to symbiont ; GO:0009608 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype <newline> negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype <newline> epithelial cell type specification, open tracheal system ; GO:0035153 | inferred from mutant phenotype <newline> glial cell migration ; GO:0008347 | inferred from mutant phenotype <newline> glial cell differentiation ; GO:0010001 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from direct assay <newline> positive regulation of S phase of mitotic cell cycle ; GO:0045750 | inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from genetic interaction with klg <newline> R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype <newline> R1/R6 cell differentiation ; GO:0048052 | inferred from mutant phenotype <newline> eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype <newline> regulation of cell differentiation ; GO:0045595 | inferred from mutant phenotype","intracellular ; GO:0005622 | inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> integral to membrane ; GO:0016021 | traceable author statement <newline> integral to plasma membrane ; GO:0005887 | non-traceable author statement <newline> intracellular ; GO:0005622 | non-traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | traceable author statement <newline> subapical complex ; GO:0035003 | inferred from direct assay <newline> adherens junction ; GO:0005912 | inferred from direct assay <newline> cytoplasmic vesicle ; GO:0031410 | colocalizes_with inferred from direct assay <newline> protein complex ; GO:0043234 | inferred from physical interaction with Su(H) <newline> integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR010660, InterPro:IPR011656","transmembrane receptor activity ; GO:0004888 | traceable author statement <newline> receptor activity ; GO:0004872 | non-traceable author statement <newline> transcription activator activity ; GO:0016563 | non-traceable author statement <newline> receptor activity ; GO:0004872 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with dx <newline> transmembrane receptor activity ; GO:0004888 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> protein binding ; GO:0005515 | inferred from physical interaction with shg <newline> transcription activator activity ; GO:0016563 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VVI3 <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9Y0H4 <newline> protein binding ; GO:0005515 | inferred from physical interaction with Su(H) <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097"]
[null,"FBgn0036285","twin of eyg","toe","The gene twin of eyg is referred to in FlyBase by the symbol Dmel\\toe (CG10704, FBgn0036285). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:12415608..12425768. It has the cytological map location 69C1. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: regulation of transcription. 6 alleles are reported. The phenotypes of these alleles are annotated with: scutum; scutellum. It has one annotated transcript and one annotated polypeptide.","regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970","nucleus ; GO:0005634 | inferred from sequence or structural similarity <newline> transcription factor complex ; GO:0005667 | inferred from sequence or structural similarity with MGD:Pax3; MGI:MGI:97487","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with MGD:Pax3; MGI:MGI:97487 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970"]
[null,"FBgn0243512","puckered","puc","The gene puckered is referred to in FlyBase by the symbol Dmel\\puc (CG7850, FBgn0243512). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3931057..3948023. It has the cytological map location 84E12-84E11. There is experimental evidence that it has the molecular function</span>: JUN kinase phosphatase activity; phosphoprotein phosphatase activity. There is experimental evidence for 20 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; organ development; organ morphogenesis; regulation of biological process; actin filament-based process; ovarian follicle cell development; regulation of developmental process; response to stress; organelle organization. 54 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; egg; cuticle; peripheral nervous system; external compound sense organ; adult segment; nervous system; chorion; adult mesothoracic segment; cuticular specialization. It has one annotated transcript and one annotated polypeptide.","imaginal disc eversion ; GO:0007561 | inferred from mutant phenotype <newline> imaginal disc fusion ; GO:0046528 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> epidermis development ; GO:0008544 | inferred from mutant phenotype <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> JNK cascade ; GO:0007254 | non-traceable author statement <newline> suture of dorsal opening ; GO:0007396 | non-traceable author statement <newline> JNK cascade ; GO:0007254 | inferred from mutant phenotype <newline> actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype <newline> protein amino acid dephosphorylation ; GO:0006470 | inferred from direct assay AND inferred from sequence or structural similarity <newline> protein amino acid dephosphorylation ; GO:0006470 | non-traceable author statement <newline> JNK cascade ; GO:0007254 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> wound healing ; GO:0042060 | inferred from expression pattern <newline> negative regulation of JNK cascade ; GO:0046329 | traceable author statement <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> response to oxidative stress ; GO:0006979 | inferred from mutant phenotype <newline> wound healing ; GO:0042060 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> negative regulation of JNK cascade ; GO:0046329 | non-traceable author statement <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> micropyle formation ; GO:0046844 | inferred from mutant phenotype <newline> wound healing ; GO:0042060 | inferred from direct assay <newline> dorsal closure ; GO:0007391 | non-traceable author statement <newline> ommatidial rotation ; GO:0016318 | non-traceable author statement <newline> establishment of planar polarity ; GO:0001736 | non-traceable author statement <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Pvr <newline> regulation of G2/M transition of mitotic cell cycle ; GO:0010389 | inferred from mutant phenotype","Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay","MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | non-traceable author statement <newline> JUN kinase phosphatase activity ; GO:0008579 | inferred from mutant phenotype <newline> phosphoprotein phosphatase activity ; GO:0004721 | inferred from direct assay <newline> protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity <newline> protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from sequence or structural similarity <newline> JUN kinase phosphatase activity ; GO:0008579 | non-traceable author statement <newline> JUN kinase phosphatase activity ; GO:0008579 | traceable author statement <newline> protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement <newline> MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | traceable author statement <newline> protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130"]
[null,"FBgn0261648","spalt major","salm","The gene spalt major is referred to in FlyBase by the symbol Dmel\\salm (CG6464, FBgn0261648). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:11434311..11445603. It has the cytological map location 32F1-32F2. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity; transcription regulator activity. There is experimental evidence that it is involved in the biological process</span>: oenocyte development; notum cell fate specification; R8 cell differentiation; sensory organ development; compound eye photoreceptor cell differentiation; spiracle morphogenesis, open tracheal system; R7 cell differentiation; open tracheal system development; antennal joint development. 28 alleles are reported. The phenotypes of these alleles are annotated with 52 unique terms, many of which group under: adult segment; adult mesothoracic segment; peripheral nervous system; organ system; nervous system; embryonic/larval tracheal system; embryonic nervous system; antennal segment; appendage segment; embryonic segment. It has one annotated transcript and one annotated polypeptide.","spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> negative regulation of transcription ; GO:0016481 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> oenocyte development ; GO:0007438 | inferred from mutant phenotype <newline> antennal joint development ; GO:0048098 | inferred from mutant phenotype <newline> R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype <newline> R8 cell differentiation ; GO:0045465 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | non-traceable author statement <newline> epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement <newline> R8 cell differentiation ; GO:0045465 | non-traceable author statement <newline> segment specification ; GO:0007379 | non-traceable author statement <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype <newline> notum cell fate specification ; GO:0035310 | inferred from mutant phenotype","nucleus ; GO:0005634 | non-traceable author statement <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> transcription regulator activity ; GO:0030528 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087"]
[]
["Leg discs development"]
[null,"FBgn0000242","Beadex","Bx","The gene Beadex is referred to in FlyBase by the symbol Dmel\\Bx (CG6500, FBgn0000242). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:18428698..18465749. It has the cytological map location 17C3-17C4. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior; leg disc development; locomotor rhythm; imaginal disc-derived wing morphogenesis; leg segmentation; response to cocaine; phagocytosis, engulfment. 87 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: adult segment; adult mesothoracic segment; organ system; peripheral nervous system; thoracic segment; appendage segment; nervous system; wing hair; dorsal thoracic disc; unguis; metatarsus. It has 3 annotated transcripts and 3 annotated polypeptides.","imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from genetic interaction with ap AND inferred from mutant phenotype <newline> leg disc development ; GO:0035218 | inferred from mutant phenotype <newline> leg segmentation ; GO:0035286 | inferred from mutant phenotype <newline> locomotor rhythm ; GO:0045475 | inferred from mutant phenotype <newline> response to cocaine ; GO:0042220 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype","nucleus ; GO:0005634 | non-traceable author statement","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781"]
[null,"FBgn0000658","four-jointed","fj","The gene four-jointed is referred to in FlyBase by the symbol Dmel\\fj (CG10917, FBgn0000658). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14120268..14123816. It has the cytological map location 55C1. There is experimental evidence that it has the molecular function</span>: protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: cell-cell signaling; imaginal disc-derived wing vein specification; establishment of epithelial cell apical/basal polarity; imaginal disc growth; imaginal disc-derived leg joint morphogenesis. 46 alleles are reported. The phenotypes of these alleles are annotated with 27 unique terms, many of which group under: adult segment; adult mesothoracic segment; appendage segment; organ system; thoracic segment; external compound sense organ; peripheral nervous system; metatarsus; antennal segment; nervous system. It has one annotated transcript and one annotated polypeptide.","cell-cell signaling ; GO:0007267 | inferred from direct assay AND inferred from sequence or structural similarity <newline> imaginal disc growth ; GO:0007446 | inferred from mutant phenotype <newline> cell-cell signaling ; GO:0007267 | inferred from expression pattern AND inferred from mutant phenotype <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype <newline> imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype <newline> establishment of epithelial cell apical/basal polarity ; GO:0045198 | inferred from mutant phenotype <newline> establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement <newline> establishment of planar polarity ; GO:0001736 | traceable author statement <newline> cell-cell signaling ; GO:0007267 | non-traceable author statement <newline> imaginal disc development ; GO:0007444 | non-traceable author statement <newline> proximal/distal pattern formation, imaginal disc ; GO:0007449 | non-traceable author statement","plasma membrane ; GO:0005886 | inferred from direct assay AND inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | non-traceable author statement","protein kinase activity ; GO:0004672 | inferred from direct assay"]
[null,"FBgn0001235","homothorax","hth","The gene homothorax is referred to in FlyBase by the symbol Dmel\\hth (CG17117, FBgn0001235). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:6335569..6464386. It has the cytological map location 86C1-86C3. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of gene-specific transcription from RNA polymerase II promoter; compound eye development; specification of segmental identity, antennal segment; specification of segmental identity, head; segmentation; compound eye photoreceptor fate commitment; brain development; imaginal disc-derived wing morphogenesis; haltere morphogenesis; imaginal disc-derived leg morphogenesis. 64 alleles are reported. The phenotypes of these alleles are annotated with 63 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; thoracic segment; external compound sense organ; appendage segment; adult mesothoracic segment; embryonic segment; embryonic nervous system; organ system; antennal segment. It has 8 annotated transcripts and 8 annotated polypeptides.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> brain development ; GO:0007420 | inferred from mutant phenotype <newline> proximal/distal pattern formation ; GO:0009954 | traceable author statement <newline> specification of organ identity ; GO:0010092 | traceable author statement <newline> compound eye photoreceptor fate commitment ; GO:0001752 | inferred from mutant phenotype <newline> leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype <newline> specification of segmental identity, antennal segment ; GO:0007383 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype <newline> haltere morphogenesis ; GO:0048735 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> transcription factor activity ; GO:0003700 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356"]
[null,"FBgn0004644","hedgehog","hh","The gene hedgehog is referred to in FlyBase by the symbol Dmel\\hh (CG4637, FBgn0004644). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:18953425..18967881. It has the cytological map location 94E1. There is experimental evidence that it has the molecular function</span>: cell surface binding; protein binding. There is experimental evidence for 24 unique biological process</span> terms, many of which group under: anatomical structure development; cellular component movement; organ morphogenesis; regulation of biological process; sensory organ development; reproductive process in a multicellular organism; organ development; regulation of protein transport; cell projection organization; open tracheal system development; central nervous system development. 170 alleles are reported. The phenotypes of these alleles are annotated with 190 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; primordium; nervous system; late extended germ band embryo; ventral nerve cord primordium; embryonic nervous system; abdominal ventral denticle belt. It has 2 annotated transcripts and 2 annotated polypeptides.","pole cell migration ; GO:0007280 | inferred from genetic interaction with Hmgcr inferred from genetic interaction with disp <newline> progression of morphogenetic furrow during compound eye morphogenesis ; GO:0007458 | inferred from expression pattern AND inferred from genetic interaction with dpp AND inferred from genetic interaction with h AND inferred from genetic interaction with sca AND inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo <newline> germ cell migration ; GO:0008354 | inferred from mutant phenotype <newline> gonadal mesoderm development ; GO:0007506 | inferred from mutant phenotype <newline> positive regulation of hh target transcription factor activity ; GO:0007228 | inferred from genetic interaction with Su(fu) AND inferred from genetic interaction with fu <newline> Bolwig's organ morphogenesis ; GO:0001746 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | traceable author statement <newline> hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype <newline> regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype <newline> epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype <newline> glial cell migration ; GO:0008347 | inferred from mutant phenotype <newline> labial disc development ; GO:0035217 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> morphogenesis of larval imaginal disc epithelium ; GO:0016335 | inferred from mutant phenotype <newline> protein autoprocessing ; GO:0016540 | inferred from direct assay AND inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | traceable author statement <newline> positive regulation of smoothened signaling pathway ; GO:0045880 | traceable author statement <newline> protein autoprocessing ; GO:0016540 | traceable author statement <newline> protein splicing ; GO:0030908 | traceable author statement <newline> cytoneme assembly ; GO:0035231 | inferred from mutant phenotype <newline> foregut morphogenesis ; GO:0007440 | traceable author statement <newline> hindgut morphogenesis ; GO:0007442 | traceable author statement <newline> anterior/posterior lineage restriction, imaginal disc ; GO:0048099 | traceable author statement <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | traceable author statement <newline> imaginal disc-derived wing vein specification ; GO:0007474 | traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> ovarian follicle cell stalk formation ; GO:0030713 | traceable author statement <newline> epidermis development ; GO:0008544 | traceable author statement <newline> growth ; GO:0040007 | non-traceable author statement <newline> germ-line stem cell division ; GO:0042078 | traceable author statement <newline> ectoderm development ; GO:0007398 | non-traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> mesoderm development ; GO:0007498 | non-traceable author statement <newline> imaginal disc pattern formation ; GO:0007447 | non-traceable author statement <newline> regulation of organ growth ; GO:0046620 | traceable author statement <newline> analia development ; GO:0007487 | traceable author statement <newline> genital disc development ; GO:0035215 | traceable author statement <newline> leg disc morphogenesis ; GO:0007478 | traceable author statement <newline> regulation of cell proliferation ; GO:0042127 | non-traceable author statement <newline> compartment pattern formation ; GO:0007386 | traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | non-traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | traceable author statement <newline> segment polarity determination ; GO:0007367 | non-traceable author statement <newline> anterior/posterior axis specification, embryo ; GO:0008595 | non-traceable author statement <newline> R8 cell fate specification ; GO:0045464 | non-traceable author statement <newline> heart development ; GO:0007507 | non-traceable author statement <newline> progression of morphogenetic furrow during compound eye morphogenesis ; GO:0007458 | traceable author statement <newline> somatic stem cell division ; GO:0048103 | traceable author statement <newline> protein autoprocessing ; GO:0016540 | non-traceable author statement <newline> wing disc proximal/distal pattern formation ; GO:0007473 | traceable author statement <newline> germ cell attraction ; GO:0035232 | traceable author statement <newline> developmental pigmentation ; GO:0048066 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> regulation of protein import into nucleus ; GO:0042306 | inferred from mutant phenotype <newline> imaginal disc growth ; GO:0007446 | traceable author statement <newline> anterior head segmentation ; GO:0035288 | traceable author statement <newline> posterior head segmentation ; GO:0035289 | traceable author statement <newline> segment polarity determination ; GO:0007367 | traceable author statement <newline> trunk segmentation ; GO:0035290 | traceable author statement <newline> genital disc development ; GO:0035215 | inferred from mutant phenotype <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | traceable author statement <newline> genital disc anterior/posterior pattern formation ; GO:0035224 | inferred from expression pattern <newline> eye morphogenesis ; GO:0048592 | inferred from mutant phenotype <newline> ventral midline development ; GO:0007418 | inferred from mutant phenotype <newline> anterior commissure morphogenesis ; GO:0021960 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from expression pattern <newline> positive regulation of transcription factor import into nucleus ; GO:0042993 | inferred from mutant phenotype <newline> cell-cell signaling ; GO:0007267 | inferred from electronic annotation with InterPro:IPR000320 <newline> proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001767 <newline> intein-mediated protein splicing ; GO:0016539 | inferred from electronic annotation with InterPro:IPR006141","extracellular region ; GO:0005576 | traceable author statement <newline> cytoplasmic membrane-bounded vesicle ; GO:0016023 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | non-traceable author statement <newline> extracellular region ; GO:0005576 | non-traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> endocytic vesicle ; GO:0030139 | inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with iHog <newline> cell surface binding ; GO:0043498 | inferred from direct assay <newline> patched binding ; GO:0005113 | traceable author statement <newline> cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity <newline> signal transducer activity ; GO:0004871 | traceable author statement <newline> morphogen activity ; GO:0016015 | traceable author statement <newline> endopeptidase activity ; GO:0004175 | non-traceable author statement <newline> patched binding ; GO:0005113 | non-traceable author statement <newline> peptidase activity ; GO:0008233 | inferred from electronic annotation with InterPro:IPR001767"]
[null,"FBgn0004647","Notch","N","The gene Notch is referred to in FlyBase by the symbol Dmel\\N (CG3936, FBgn0004647). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3028905..3066295. It has the cytological map location 3C7-3C9. There is experimental evidence that it has the molecular function</span>: protein binding; specific transcriptional repressor activity; transcription activator activity. There is experimental evidence for 54 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; organ development; regulation of developmental process; sensory organ development; organ morphogenesis; regulation of neurogenesis; cellular component movement; ovarian follicle cell development; regulation of biological process. 653 alleles are reported. The phenotypes of these alleles are annotated with 219 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; adult mesothoracic segment; organ system; external compound sense organ; embryonic nervous system; multi-cell-component structure; primordium; embryonic neuron. It has one annotated transcript and one annotated polypeptide.","stem cell differentiation ; GO:0048863 | inferred from mutant phenotype <newline> regulation of neurogenesis ; GO:0050767 | inferred from mutant phenotype <newline> ectoderm development ; GO:0007398 | traceable author statement <newline> mesoderm development ; GO:0007498 | inferred from mutant phenotype <newline> ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> leg joint morphogenesis ; GO:0035111 | inferred from mutant phenotype <newline> leg segmentation ; GO:0035286 | inferred from mutant phenotype <newline> R8 cell development ; GO:0045463 | traceable author statement <newline> cell adhesion ; GO:0007155 | traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> glial cell fate determination ; GO:0007403 | inferred from mutant phenotype <newline> peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype <newline> germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> muscle cell fate determination ; GO:0007521 | inferred from mutant phenotype <newline> regulation of cardioblast cell fate specification ; GO:0042686 | inferred from mutant phenotype <newline> regulation of growth ; GO:0040008 | inferred from genetic interaction with scrib AND inferred from mutant phenotype <newline> foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype <newline> oocyte localization during germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> anesthesia-resistant memory ; GO:0007615 | NOT inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from mutant phenotype <newline> lateral inhibition ; GO:0046331 | traceable author statement <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype <newline> cell fate specification ; GO:0001708 | traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> anterior/posterior pattern formation ; GO:0009952 | traceable author statement <newline> leg disc morphogenesis ; GO:0007478 | traceable author statement <newline> cell fate commitment ; GO:0045165 | non-traceable author statement <newline> negative regulation of fusion cell fate specification ; GO:0035157 | traceable author statement <newline> negative regulation of terminal cell fate specification, open tracheal system ; GO:0035155 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> imaginal disc growth ; GO:0007446 | traceable author statement <newline> imaginal disc pattern formation ; GO:0007447 | traceable author statement <newline> skeletal muscle tissue development ; GO:0007519 | inferred from mutant phenotype <newline> ovarian follicle cell stalk formation ; GO:0030713 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> germarium-derived egg chamber formation ; GO:0007293 | traceable author statement <newline> germarium-derived female germ-line cyst encapsulation ; GO:0030708 | traceable author statement <newline> morphogenesis of follicular epithelium ; GO:0016333 | non-traceable author statement <newline> oocyte anterior/posterior axis specification ; GO:0007314 | traceable author statement <newline> dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | traceable author statement <newline> establishment of ommatidial planar polarity ; GO:0042067 | non-traceable author statement <newline> cell fate specification ; GO:0001708 | non-traceable author statement <newline> compound eye retinal cell programmed cell death ; GO:0046667 | traceable author statement <newline> second mitotic wave during compound eye morphogenesis ; GO:0016330 | non-traceable author statement <newline> R8 cell differentiation ; GO:0045465 | non-traceable author statement <newline> regulation of R8 cell spacing in compound eye ; GO:0045468 | non-traceable author statement <newline> dorsal/ventral pattern formation, imaginal disc ; GO:0007450 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> lateral inhibition ; GO:0046331 | non-traceable author statement <newline> negative regulation of JNK cascade ; GO:0046329 | non-traceable author statement <newline> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | NOT non-traceable author statement <newline> establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement <newline> crystal cell differentiation ; GO:0042688 | inferred from mutant phenotype <newline> embryonic hemopoiesis ; GO:0035162 | inferred from mutant phenotype <newline> hemocyte proliferation ; GO:0035172 | inferred from mutant phenotype <newline> larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype <newline> R3/R4 cell fate commitment ; GO:0007464 | non-traceable author statement <newline> retinal cell programmed cell death ; GO:0046666 | traceable author statement <newline> wing disc proximal/distal pattern formation ; GO:0007473 | traceable author statement <newline> regulation of crystal cell differentiation ; GO:0042689 | traceable author statement <newline> asymmetric cell division ; GO:0008356 | traceable author statement <newline> ventral cord development ; GO:0007419 | non-traceable author statement <newline> R7 cell differentiation ; GO:0045466 | traceable author statement <newline> regulation of mitotic cell cycle ; GO:0007346 | traceable author statement <newline> lymph gland crystal cell differentiation ; GO:0035170 | traceable author statement <newline> embryonic crystal cell differentiation ; GO:0035165 | traceable author statement <newline> long-term memory ; GO:0007616 | traceable author statement <newline> lymph gland development ; GO:0048542 | inferred from mutant phenotype <newline> negative regulation of compound eye photoreceptor development ; GO:0045316 | inferred from mutant phenotype <newline> positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> compound eye cone cell fate commitment ; GO:0042676 | traceable author statement <newline> compound eye development ; GO:0048749 | non-traceable author statement <newline> compound eye development ; GO:0048749 | traceable author statement <newline> R8 cell fate commitment ; GO:0007460 | traceable author statement <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> heterophilic cell-cell adhesion ; GO:0007157 | inferred from mutant phenotype inferred from direct assay <newline> positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype <newline> lamellocyte differentiation ; GO:0035171 | inferred from mutant phenotype <newline> response to symbiont ; GO:0009608 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype <newline> negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype <newline> epithelial cell type specification, open tracheal system ; GO:0035153 | inferred from mutant phenotype <newline> glial cell migration ; GO:0008347 | inferred from mutant phenotype <newline> glial cell differentiation ; GO:0010001 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from direct assay <newline> positive regulation of S phase of mitotic cell cycle ; GO:0045750 | inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from genetic interaction with klg <newline> R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype <newline> R1/R6 cell differentiation ; GO:0048052 | inferred from mutant phenotype <newline> eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype <newline> regulation of cell differentiation ; GO:0045595 | inferred from mutant phenotype","intracellular ; GO:0005622 | inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> integral to membrane ; GO:0016021 | traceable author statement <newline> integral to plasma membrane ; GO:0005887 | non-traceable author statement <newline> intracellular ; GO:0005622 | non-traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | traceable author statement <newline> subapical complex ; GO:0035003 | inferred from direct assay <newline> adherens junction ; GO:0005912 | inferred from direct assay <newline> cytoplasmic vesicle ; GO:0031410 | colocalizes_with inferred from direct assay <newline> protein complex ; GO:0043234 | inferred from physical interaction with Su(H) <newline> integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR010660, InterPro:IPR011656","transmembrane receptor activity ; GO:0004888 | traceable author statement <newline> receptor activity ; GO:0004872 | non-traceable author statement <newline> transcription activator activity ; GO:0016563 | non-traceable author statement <newline> receptor activity ; GO:0004872 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with dx <newline> transmembrane receptor activity ; GO:0004888 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> protein binding ; GO:0005515 | inferred from physical interaction with shg <newline> transcription activator activity ; GO:0016563 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VVI3 <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9Y0H4 <newline> protein binding ; GO:0005515 | inferred from physical interaction with Su(H) <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097"]
[null,"FBgn0004854","BarH2","B-H2","The gene BarH2 is referred to in FlyBase by the symbol Dmel\\B-H2 (CG5488, FBgn0004854). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:17208614..17218195. It has the cytological map location 16A1. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity; DNA binding; transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: sensory organ boundary specification; compound eye photoreceptor cell differentiation; leg disc proximal/distal pattern formation; eye-antennal disc morphogenesis; eye pigment granule organization; bristle morphogenesis. 8 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; thoracic segment; metatarsus; organ system; peripheral nervous system; appendage segment; adult mesothoracic segment; nervous system; eipithelial furrow; external compound sense organ. It has one annotated transcript and one annotated polypeptide.","sensory organ boundary specification ; GO:0008052 | inferred from mutant phenotype <newline> eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype <newline> leg disc proximal/distal pattern formation ; GO:0007479 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970","nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR017970","specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001356"]
[null,"FBgn0005511","midline","mid","The gene midline is referred to in FlyBase by the symbol Dmel\\mid (CG6634, FBgn0005511). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:5461641..5467609. It has the cytological map location 25E2. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence for 12 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; regulation of biological process; regulation of developmental process; stem cell differentiation; neuroblast fate commitment; embryonic pattern specification; regulation of metabolic process; regionalization; neuroblast development; regulation of cell fate specification; cellular component movement; embryonic heart tube development; leg disc development; central nervous system development. 15 alleles are reported. The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: organ system; embryonic nervous system; primordium; adult segment; nervous system; cuticle; organ system subdivision; embryonic/larval dorsal vessel; peripheral nervous system; embryonic neuron. It has one annotated transcript and one annotated polypeptide.","segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> heart development ; GO:0007507 | inferred from mutant phenotype <newline> cardioblast cell fate commitment ; GO:0042684 | inferred from mutant phenotype <newline> embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype <newline> regulation of cardioblast differentiation ; GO:0051890 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with EMBL:AC006379; protein_id:AAD21787.1 <newline> neuroblast fate specification ; GO:0014018 | inferred from mutant phenotype <newline> neuroblast development ; GO:0014019 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> central nervous system development ; GO:0007417 | inferred from mutant phenotype inferred from genetic interaction with HGTX <newline> negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype inferred from genetic interaction with HGTX <newline> leg disc pattern formation ; GO:0035223 | inferred from genetic interaction with H15 <newline> regulation of cell fate specification ; GO:0042659 | inferred from genetic interaction with H15 <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001699, InterPro:IPR018186","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:AC006379; protein_id:AAD21787.1","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:AC006379; protein_id:AAD21787.1"]
[null,"FBgn0010762","simjang","simj","The gene simjang is referred to in FlyBase by the symbol Dmel\\simj (CG32067, FBgn0010762). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:10657843..10682480. It has the cytological map location 67E6. Based on sequence similarity, it is predicted to have molecular function</span>: transcription repressor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: negative regulation of transcription, DNA-dependent. 51 alleles are reported. The phenotypes of these alleles are annotated with: leg; embryonic heart; scutellar bristle; wing; cardioblast; pupal abdomen. It has 3 annotated transcripts and 3 annotated polypeptides.","negative regulation of transcription, DNA-dependent ; GO:0045892 | inferred from sequence or structural similarity with EMBL:AF411837; protein_id:AAL39081.1","nucleus ; GO:0005634 | inferred from direct assay","transcription repressor activity ; GO:0016564 | inferred from sequence or structural similarity with EMBL:AF411837; protein_id:AAL39081.1"]
[null,"FBgn0011591","fringe","fng","The gene fringe is referred to in FlyBase by the symbol Dmel\\fng (CG10580, FBgn0011591). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20918983..20942609. It has the cytological map location 78A1. There is experimental evidence that it has the molecular function</span>: UDP-glycosyltransferase activity; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity; acetylglucosaminyltransferase activity. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; organ morphogenesis; regulation of biological process; leg morphogenesis; sensory organ development; leg segmentation; biopolymer modification; hexose metabolic process; regionalization; appendage development; compound eye development. 66 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; female germline cyst; late extended germ band embryo; nervous system; ectoderm derivative; external compound sense organ; primordium. It has one annotated transcript and one annotated polypeptide.","imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> dorsal/ventral pattern formation, imaginal disc ; GO:0007450 | inferred from direct assay <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from direct assay <newline> leg joint morphogenesis ; GO:0035111 | inferred from mutant phenotype <newline> leg segmentation ; GO:0035286 | inferred from mutant phenotype <newline> Notch signaling pathway ; GO:0007219 | inferred from direct assay <newline> fucose metabolic process ; GO:0006004 | inferred from direct assay <newline> germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype <newline> regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype <newline> positive regulation of Notch signaling pathway ; GO:0045747 | non-traceable author statement <newline> Notch signaling pathway ; GO:0007219 | traceable author statement <newline> dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | traceable author statement <newline> regulation of Notch signaling pathway ; GO:0008593 | traceable author statement <newline> negative regulation of Notch signaling pathway ; GO:0045746 | non-traceable author statement <newline> regulation of Notch signaling pathway ; GO:0008593 | non-traceable author statement <newline> cell fate specification ; GO:0001708 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from direct assay <newline> oogenesis ; GO:0048477 | traceable author statement <newline> regulation of Notch signaling pathway ; GO:0008593 | inferred from direct assay <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> protein amino acid O-linked glycosylation ; GO:0006493 | inferred from mutant phenotype <newline> fucose metabolic process ; GO:0006004 | inferred from mutant phenotype","Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> Golgi apparatus ; GO:0005794 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | non-traceable author statement <newline> Golgi stack ; GO:0005795 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> Golgi apparatus ; GO:0005794 | traceable author statement <newline> integral to Golgi membrane ; GO:0030173 | inferred from electronic annotation with InterPro:IPR017374","UDP-glycosyltransferase activity ; GO:0008194 | inferred from direct assay <newline> acetylglucosaminyltransferase activity ; GO:0008375 | inferred from direct assay <newline> acetylglucosaminyltransferase activity ; GO:0008375 | non-traceable author statement <newline> acetylglucosaminyltransferase activity ; GO:0008375 | traceable author statement <newline> O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity ; GO:0033829 | inferred from direct assay"]
[null,"FBgn0086902","kismet","kis","The gene kismet is referred to in FlyBase by the symbol Dmel\\kis (CG3696, FBgn0086902). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:210732..250795. It has the cytological map location 21B4-21B5. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent helicase activity. There is experimental evidence that it is involved in the biological process</span>: blastoderm segmentation; segment specification; border follicle cell migration; axon guidance; antimicrobial humoral response. 128 alleles are reported. The phenotypes of these alleles are annotated with: leg; imaginal disc. It has 3 annotated transcripts and 3 annotated polypeptides.","blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype <newline> segment specification ; GO:0007379 | inferred from mutant phenotype <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> chromatin assembly or disassembly ; GO:0006333 | inferred from electronic annotation with InterPro:IPR000953","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with InterPro:IPR000953 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay <newline> chromatin ; GO:0000785 | inferred from electronic annotation with InterPro:IPR000953","ATP-dependent helicase activity ; GO:0008026 | inferred from sequence or structural similarity with InterPro:IPR001410 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330, InterPro:IPR001650 <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000330 <newline> chromatin binding ; GO:0003682 | inferred from electronic annotation with InterPro:IPR000953"]
[null,"FBgn0087007","big bang","bbg","The gene big bang is referred to in FlyBase by the symbol Dmel\\bbg (CG42230, FBgn0087007). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: imaginal disc development. 39 alleles are reported. The phenotype of these alleles is annotated with: imaginal disc. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: PDZ/DHR/GLGF. Gene sequence location is 3L:14405921..14506348.","imaginal disc development ; GO:0007444 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay","-"]
[]
["Eye disc/omatidia development"]
[null,"FBgn0000575","extra macrochaetae","emc","The gene extra macrochaetae is referred to in FlyBase by the symbol Dmel\\emc (CG1007, FBgn0000575). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:749406..753505. It has the cytological map location 61C9. There is experimental evidence that it has the molecular function</span>: transcription repressor activity; protein heterodimerization activity. There is experimental evidence for 19 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; sensory organ development; organ development; behavior; reproductive process in a multicellular organism; cell proliferation; negative regulation of molecular function; compound eye cone cell differentiation; embryonic development via the syncytial blastoderm; locomotory behavior; negative regulation of cellular biosynthetic process; reproductive developmental process; neuromuscular process; behavioral interaction between organisms. 94 alleles are reported. The phenotypes of these alleles are annotated with 42 unique terms, many of which group under: peripheral nervous system; organ system; nervous system; adult segment; external compound sense organ; adult mesothoracic segment; primordium; female germline cyst; midgut constriction; germ layer; Malpighian tubule. It has one annotated transcript and one annotated polypeptide.","negative regulation of transcription ; GO:0016481 | traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> sensory organ development ; GO:0007423 | traceable author statement <newline> sex determination ; GO:0007530 | inferred from genetic interaction with dpn, Sxl <newline> spermatid development ; GO:0007286 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from genetic interaction with Egfr AND inferred from genetic interaction with vn AND inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from genetic interaction with Egfr AND inferred from genetic interaction with vn AND inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from genetic interaction with bs AND inferred from genetic interaction with net AND inferred from genetic interaction with px AND inferred from mutant phenotype <newline> negative regulation of transcription ; GO:0016481 | non-traceable author statement <newline> sensory organ development ; GO:0007423 | non-traceable author statement <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | non-traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> sex determination, primary response to X:A ratio ; GO:0007541 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype <newline> bristle morphogenesis ; GO:0008407 | traceable author statement <newline> R8 cell fate commitment ; GO:0007460 | non-traceable author statement <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> midgut development ; GO:0007494 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> brain morphogenesis ; GO:0048854 | inferred from mutant phenotype <newline> startle response ; GO:0001964 | inferred from mutant phenotype <newline> locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype <newline> R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype <newline> compound eye cone cell differentiation ; GO:0042675 | inferred from mutant phenotype <newline> progression of morphogenetic furrow during compound eye morphogenesis ; GO:0007458 | inferred from mutant phenotype <newline> R3/R4 cell differentiation ; GO:0048056 | inferred from mutant phenotype <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype <newline> negative regulation of DNA binding ; GO:0043392 | inferred from direct assay <newline> negative regulation of transcription ; GO:0016481 | inferred from direct assay","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P41137 <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from direct assay","transcription corepressor activity ; GO:0003714 | inferred from sequence or structural similarity with UniProtKB:P41137 <newline> protein binding ; GO:0005515 | non-traceable author statement <newline> transcription corepressor activity ; GO:0003714 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | inferred from direct assay <newline> protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da inferred from physical interaction with ac inferred from physical interaction with sc inferred from physical interaction with l(1)sc <newline> protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da"]
[null,"FBgn0000625","eyegone","eyg","The gene eyegone is referred to in FlyBase by the symbol Dmel\\eyg (CG10488, FBgn0000625). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:12456132..12461121. It has the cytological map location 69C2. There is experimental evidence that it has the molecular function</span>: transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: notum development; eye development; antennal development; eye-antennal disc development; compound eye development; compound eye morphogenesis. 54 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: adult segment; adult mesothoracic segment; peripheral nervous system; nervous system; organ system; imaginal precursor; external compound sense organ; integumentary plate; salivary gland imaginal ring; dorsal thoracic disc. It has 2 annotated transcripts and 2 annotated polypeptides.","eye development ; GO:0001654 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> antennal development ; GO:0007469 | inferred from mutant phenotype <newline> notum development ; GO:0007477 | inferred from mutant phenotype <newline> eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970","transcription factor complex ; GO:0005667 | inferred from sequence or structural similarity with MGD:Pax3; MGI:MGI:97487","transcription repressor activity ; GO:0016564 | inferred from mutant phenotype <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with MGD:Pax3; MGI:MGI:97487 <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970"]
[null,"FBgn0001235","homothorax","hth","The gene homothorax is referred to in FlyBase by the symbol Dmel\\hth (CG17117, FBgn0001235). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:6335569..6464386. It has the cytological map location 86C1-86C3. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of gene-specific transcription from RNA polymerase II promoter; compound eye development; specification of segmental identity, antennal segment; specification of segmental identity, head; segmentation; compound eye photoreceptor fate commitment; brain development; imaginal disc-derived wing morphogenesis; haltere morphogenesis; imaginal disc-derived leg morphogenesis. 64 alleles are reported. The phenotypes of these alleles are annotated with 63 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; thoracic segment; external compound sense organ; appendage segment; adult mesothoracic segment; embryonic segment; embryonic nervous system; organ system; antennal segment. It has 8 annotated transcripts and 8 annotated polypeptides.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> brain development ; GO:0007420 | inferred from mutant phenotype <newline> proximal/distal pattern formation ; GO:0009954 | traceable author statement <newline> specification of organ identity ; GO:0010092 | traceable author statement <newline> compound eye photoreceptor fate commitment ; GO:0001752 | inferred from mutant phenotype <newline> leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype <newline> specification of segmental identity, antennal segment ; GO:0007383 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype <newline> haltere morphogenesis ; GO:0048735 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> transcription factor activity ; GO:0003700 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356"]
[null,"FBgn0003174","pawn","pwn","The gene pawn is referred to in FlyBase by the symbol Dmel\\pwn (CG11101, FBgn0003174). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3182813..3187907. It has the cytological map location 43A3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: calcium ion binding. There is experimental evidence that it is involved in the biological process</span>: phototransduction; bristle morphogenesis. 14 alleles are reported. The phenotypes of these alleles are annotated with: cornea; eye; retina; macrochaeta; chaeta. It has one annotated transcript and one annotated polypeptide.","bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> phototransduction ; GO:0007602 | inferred from mutant phenotype","-","calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097"]
[null,"FBgn0003310","Star","S","The gene Star is referred to in FlyBase by the symbol Dmel\\S (CG4385, FBgn0003310). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:1050877..1077811. It has the cytological map location 21E4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: epidermal growth factor ligand processing; stomatogastric nervous system development; determination of genital disc primordium; protein targeting to Golgi; compound eye retinal cell programmed cell death; regulation of epidermal growth factor receptor signaling pathway; ommatidial rotation; imaginal disc-derived wing morphogenesis; behavioral response to ethanol. 151 alleles are reported. The phenotypes of these alleles are annotated with 58 unique terms, many of which group under: organ system; embryonic nervous system; peripheral nervous system; nervous system; adult segment; external compound sense organ; adult mesothoracic segment; embryonic neuron; multi-cell-component structure; female germline cyst; commissure. It has 2 annotated transcripts and 2 annotated polypeptides.","epidermal growth factor ligand processing ; GO:0007174 | inferred from genetic interaction with spi <newline> protein targeting to Golgi ; GO:0000042 | inferred from genetic interaction with spi <newline> regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from genetic interaction with rho, spi <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | traceable author statement <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | non-traceable author statement <newline> compound eye photoreceptor development ; GO:0042051 | non-traceable author statement <newline> protein targeting to Golgi ; GO:0000042 | non-traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> embryonic development ; GO:0009790 | traceable author statement <newline> mesoderm development ; GO:0007498 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> photoreceptor cell development ; GO:0042461 | traceable author statement <newline> regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | traceable author statement <newline> protein targeting to Golgi ; GO:0000042 | traceable author statement <newline> determination of genital disc primordium ; GO:0035225 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | traceable author statement <newline> behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype <newline> stomatogastric nervous system development ; GO:0007421 | inferred from mutant phenotype <newline> compound eye retinal cell programmed cell death ; GO:0046667 | inferred from mutant phenotype <newline> ommatidial rotation ; GO:0016318 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> membrane ; GO:0016020 | non-traceable author statement <newline> Golgi apparatus ; GO:0005794 | non-traceable author statement <newline> endoplasmic reticulum ; GO:0005783 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | traceable author statement","-"]
[null,"FBgn0003326","scabrous","sca","The gene scabrous is referred to in FlyBase by the symbol Dmel\\sca (CG17579, FBgn0003326). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8668049..8689515. It has the cytological map location 49C3-49D3. It is reported to have molecular function</span>: signal transducer activity. There is experimental evidence that it is involved in the biological process</span>: female meiosis chromosome segregation; compound eye development; imaginal disc-derived wing margin morphogenesis; nervous system development; ommatidial rotation; bristle morphogenesis. 71 alleles are reported. The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: peripheral nervous system; nervous system; adult segment; external compound sense organ; organ system; adult mesothoracic segment; plasma membrane part; plasma membrane; eo support cell; acrostichal bristle; imaginal precursor; adult cuticle; antennal segment. It has 2 annotated transcripts and 2 annotated polypeptides.","bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | inferred from genetic interaction with N <newline> female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype <newline> ommatidial rotation ; GO:0016318 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> lateral inhibition ; GO:0046331 | non-traceable author statement <newline> regulation of R8 cell spacing in compound eye ; GO:0045468 | traceable author statement <newline> regulation of R8 cell spacing in compound eye ; GO:0045468 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from genetic interaction with hh AND inferred from mutant phenotype <newline> R8 cell fate commitment ; GO:0007460 | traceable author statement <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002181, InterPro:IPR014716","fibrinogen complex ; GO:0005577 | inferred from sequence or structural similarity with NCBI_gi:4758348 <newline> extracellular region ; GO:0005576 | non-traceable author statement","signal transducer activity ; GO:0004871 | traceable author statement <newline> receptor binding ; GO:0005102 | inferred from electronic annotation with InterPro:IPR002181, InterPro:IPR014716"]
[null,"FBgn0004644","hedgehog","hh","The gene hedgehog is referred to in FlyBase by the symbol Dmel\\hh (CG4637, FBgn0004644). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:18953425..18967881. It has the cytological map location 94E1. There is experimental evidence that it has the molecular function</span>: cell surface binding; protein binding. There is experimental evidence for 24 unique biological process</span> terms, many of which group under: anatomical structure development; cellular component movement; organ morphogenesis; regulation of biological process; sensory organ development; reproductive process in a multicellular organism; organ development; regulation of protein transport; cell projection organization; open tracheal system development; central nervous system development. 170 alleles are reported. The phenotypes of these alleles are annotated with 190 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; primordium; nervous system; late extended germ band embryo; ventral nerve cord primordium; embryonic nervous system; abdominal ventral denticle belt. It has 2 annotated transcripts and 2 annotated polypeptides.","pole cell migration ; GO:0007280 | inferred from genetic interaction with Hmgcr inferred from genetic interaction with disp <newline> progression of morphogenetic furrow during compound eye morphogenesis ; GO:0007458 | inferred from expression pattern AND inferred from genetic interaction with dpp AND inferred from genetic interaction with h AND inferred from genetic interaction with sca AND inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from genetic interaction with smo <newline> germ cell migration ; GO:0008354 | inferred from mutant phenotype <newline> gonadal mesoderm development ; GO:0007506 | inferred from mutant phenotype <newline> positive regulation of hh target transcription factor activity ; GO:0007228 | inferred from genetic interaction with Su(fu) AND inferred from genetic interaction with fu <newline> Bolwig's organ morphogenesis ; GO:0001746 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | traceable author statement <newline> hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype <newline> regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype <newline> epithelial cell migration, open tracheal system ; GO:0007427 | inferred from mutant phenotype <newline> glial cell migration ; GO:0008347 | inferred from mutant phenotype <newline> labial disc development ; GO:0035217 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> morphogenesis of larval imaginal disc epithelium ; GO:0016335 | inferred from mutant phenotype <newline> protein autoprocessing ; GO:0016540 | inferred from direct assay AND inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | traceable author statement <newline> positive regulation of smoothened signaling pathway ; GO:0045880 | traceable author statement <newline> protein autoprocessing ; GO:0016540 | traceable author statement <newline> protein splicing ; GO:0030908 | traceable author statement <newline> cytoneme assembly ; GO:0035231 | inferred from mutant phenotype <newline> foregut morphogenesis ; GO:0007440 | traceable author statement <newline> hindgut morphogenesis ; GO:0007442 | traceable author statement <newline> anterior/posterior lineage restriction, imaginal disc ; GO:0048099 | traceable author statement <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | traceable author statement <newline> imaginal disc-derived wing vein specification ; GO:0007474 | traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> ovarian follicle cell stalk formation ; GO:0030713 | traceable author statement <newline> epidermis development ; GO:0008544 | traceable author statement <newline> growth ; GO:0040007 | non-traceable author statement <newline> germ-line stem cell division ; GO:0042078 | traceable author statement <newline> ectoderm development ; GO:0007398 | non-traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> mesoderm development ; GO:0007498 | non-traceable author statement <newline> imaginal disc pattern formation ; GO:0007447 | non-traceable author statement <newline> regulation of organ growth ; GO:0046620 | traceable author statement <newline> analia development ; GO:0007487 | traceable author statement <newline> genital disc development ; GO:0035215 | traceable author statement <newline> leg disc morphogenesis ; GO:0007478 | traceable author statement <newline> regulation of cell proliferation ; GO:0042127 | non-traceable author statement <newline> compartment pattern formation ; GO:0007386 | traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | non-traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | traceable author statement <newline> segment polarity determination ; GO:0007367 | non-traceable author statement <newline> anterior/posterior axis specification, embryo ; GO:0008595 | non-traceable author statement <newline> R8 cell fate specification ; GO:0045464 | non-traceable author statement <newline> heart development ; GO:0007507 | non-traceable author statement <newline> progression of morphogenetic furrow during compound eye morphogenesis ; GO:0007458 | traceable author statement <newline> somatic stem cell division ; GO:0048103 | traceable author statement <newline> protein autoprocessing ; GO:0016540 | non-traceable author statement <newline> wing disc proximal/distal pattern formation ; GO:0007473 | traceable author statement <newline> germ cell attraction ; GO:0035232 | traceable author statement <newline> developmental pigmentation ; GO:0048066 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> regulation of protein import into nucleus ; GO:0042306 | inferred from mutant phenotype <newline> imaginal disc growth ; GO:0007446 | traceable author statement <newline> anterior head segmentation ; GO:0035288 | traceable author statement <newline> posterior head segmentation ; GO:0035289 | traceable author statement <newline> segment polarity determination ; GO:0007367 | traceable author statement <newline> trunk segmentation ; GO:0035290 | traceable author statement <newline> genital disc development ; GO:0035215 | inferred from mutant phenotype <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | traceable author statement <newline> genital disc anterior/posterior pattern formation ; GO:0035224 | inferred from expression pattern <newline> eye morphogenesis ; GO:0048592 | inferred from mutant phenotype <newline> ventral midline development ; GO:0007418 | inferred from mutant phenotype <newline> anterior commissure morphogenesis ; GO:0021960 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from expression pattern <newline> positive regulation of transcription factor import into nucleus ; GO:0042993 | inferred from mutant phenotype <newline> cell-cell signaling ; GO:0007267 | inferred from electronic annotation with InterPro:IPR000320 <newline> proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001767 <newline> intein-mediated protein splicing ; GO:0016539 | inferred from electronic annotation with InterPro:IPR006141","extracellular region ; GO:0005576 | traceable author statement <newline> cytoplasmic membrane-bounded vesicle ; GO:0016023 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | non-traceable author statement <newline> extracellular region ; GO:0005576 | non-traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> endocytic vesicle ; GO:0030139 | inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with iHog <newline> cell surface binding ; GO:0043498 | inferred from direct assay <newline> patched binding ; GO:0005113 | traceable author statement <newline> cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity <newline> signal transducer activity ; GO:0004871 | traceable author statement <newline> morphogen activity ; GO:0016015 | traceable author statement <newline> endopeptidase activity ; GO:0004175 | non-traceable author statement <newline> patched binding ; GO:0005113 | non-traceable author statement <newline> peptidase activity ; GO:0008233 | inferred from electronic annotation with InterPro:IPR001767"]
[null,"FBgn0004647","Notch","N","The gene Notch is referred to in FlyBase by the symbol Dmel\\N (CG3936, FBgn0004647). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3028905..3066295. It has the cytological map location 3C7-3C9. There is experimental evidence that it has the molecular function</span>: protein binding; specific transcriptional repressor activity; transcription activator activity. There is experimental evidence for 54 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; organ development; regulation of developmental process; sensory organ development; organ morphogenesis; regulation of neurogenesis; cellular component movement; ovarian follicle cell development; regulation of biological process. 653 alleles are reported. The phenotypes of these alleles are annotated with 219 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; adult mesothoracic segment; organ system; external compound sense organ; embryonic nervous system; multi-cell-component structure; primordium; embryonic neuron. It has one annotated transcript and one annotated polypeptide.","stem cell differentiation ; GO:0048863 | inferred from mutant phenotype <newline> regulation of neurogenesis ; GO:0050767 | inferred from mutant phenotype <newline> ectoderm development ; GO:0007398 | traceable author statement <newline> mesoderm development ; GO:0007498 | inferred from mutant phenotype <newline> ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> leg joint morphogenesis ; GO:0035111 | inferred from mutant phenotype <newline> leg segmentation ; GO:0035286 | inferred from mutant phenotype <newline> R8 cell development ; GO:0045463 | traceable author statement <newline> cell adhesion ; GO:0007155 | traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> glial cell fate determination ; GO:0007403 | inferred from mutant phenotype <newline> peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype <newline> germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> muscle cell fate determination ; GO:0007521 | inferred from mutant phenotype <newline> regulation of cardioblast cell fate specification ; GO:0042686 | inferred from mutant phenotype <newline> regulation of growth ; GO:0040008 | inferred from genetic interaction with scrib AND inferred from mutant phenotype <newline> foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype <newline> oocyte localization during germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> anesthesia-resistant memory ; GO:0007615 | NOT inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from mutant phenotype <newline> lateral inhibition ; GO:0046331 | traceable author statement <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype <newline> cell fate specification ; GO:0001708 | traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> anterior/posterior pattern formation ; GO:0009952 | traceable author statement <newline> leg disc morphogenesis ; GO:0007478 | traceable author statement <newline> cell fate commitment ; GO:0045165 | non-traceable author statement <newline> negative regulation of fusion cell fate specification ; GO:0035157 | traceable author statement <newline> negative regulation of terminal cell fate specification, open tracheal system ; GO:0035155 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> imaginal disc growth ; GO:0007446 | traceable author statement <newline> imaginal disc pattern formation ; GO:0007447 | traceable author statement <newline> skeletal muscle tissue development ; GO:0007519 | inferred from mutant phenotype <newline> ovarian follicle cell stalk formation ; GO:0030713 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> germarium-derived egg chamber formation ; GO:0007293 | traceable author statement <newline> germarium-derived female germ-line cyst encapsulation ; GO:0030708 | traceable author statement <newline> morphogenesis of follicular epithelium ; GO:0016333 | non-traceable author statement <newline> oocyte anterior/posterior axis specification ; GO:0007314 | traceable author statement <newline> dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | traceable author statement <newline> establishment of ommatidial planar polarity ; GO:0042067 | non-traceable author statement <newline> cell fate specification ; GO:0001708 | non-traceable author statement <newline> compound eye retinal cell programmed cell death ; GO:0046667 | traceable author statement <newline> second mitotic wave during compound eye morphogenesis ; GO:0016330 | non-traceable author statement <newline> R8 cell differentiation ; GO:0045465 | non-traceable author statement <newline> regulation of R8 cell spacing in compound eye ; GO:0045468 | non-traceable author statement <newline> dorsal/ventral pattern formation, imaginal disc ; GO:0007450 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> lateral inhibition ; GO:0046331 | non-traceable author statement <newline> negative regulation of JNK cascade ; GO:0046329 | non-traceable author statement <newline> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | NOT non-traceable author statement <newline> establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement <newline> crystal cell differentiation ; GO:0042688 | inferred from mutant phenotype <newline> embryonic hemopoiesis ; GO:0035162 | inferred from mutant phenotype <newline> hemocyte proliferation ; GO:0035172 | inferred from mutant phenotype <newline> larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype <newline> R3/R4 cell fate commitment ; GO:0007464 | non-traceable author statement <newline> retinal cell programmed cell death ; GO:0046666 | traceable author statement <newline> wing disc proximal/distal pattern formation ; GO:0007473 | traceable author statement <newline> regulation of crystal cell differentiation ; GO:0042689 | traceable author statement <newline> asymmetric cell division ; GO:0008356 | traceable author statement <newline> ventral cord development ; GO:0007419 | non-traceable author statement <newline> R7 cell differentiation ; GO:0045466 | traceable author statement <newline> regulation of mitotic cell cycle ; GO:0007346 | traceable author statement <newline> lymph gland crystal cell differentiation ; GO:0035170 | traceable author statement <newline> embryonic crystal cell differentiation ; GO:0035165 | traceable author statement <newline> long-term memory ; GO:0007616 | traceable author statement <newline> lymph gland development ; GO:0048542 | inferred from mutant phenotype <newline> negative regulation of compound eye photoreceptor development ; GO:0045316 | inferred from mutant phenotype <newline> positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> compound eye cone cell fate commitment ; GO:0042676 | traceable author statement <newline> compound eye development ; GO:0048749 | non-traceable author statement <newline> compound eye development ; GO:0048749 | traceable author statement <newline> R8 cell fate commitment ; GO:0007460 | traceable author statement <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> heterophilic cell-cell adhesion ; GO:0007157 | inferred from mutant phenotype inferred from direct assay <newline> positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype <newline> lamellocyte differentiation ; GO:0035171 | inferred from mutant phenotype <newline> response to symbiont ; GO:0009608 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype <newline> negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype <newline> epithelial cell type specification, open tracheal system ; GO:0035153 | inferred from mutant phenotype <newline> glial cell migration ; GO:0008347 | inferred from mutant phenotype <newline> glial cell differentiation ; GO:0010001 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from direct assay <newline> positive regulation of S phase of mitotic cell cycle ; GO:0045750 | inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from genetic interaction with klg <newline> R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype <newline> R1/R6 cell differentiation ; GO:0048052 | inferred from mutant phenotype <newline> eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype <newline> regulation of cell differentiation ; GO:0045595 | inferred from mutant phenotype","intracellular ; GO:0005622 | inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> integral to membrane ; GO:0016021 | traceable author statement <newline> integral to plasma membrane ; GO:0005887 | non-traceable author statement <newline> intracellular ; GO:0005622 | non-traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | traceable author statement <newline> subapical complex ; GO:0035003 | inferred from direct assay <newline> adherens junction ; GO:0005912 | inferred from direct assay <newline> cytoplasmic vesicle ; GO:0031410 | colocalizes_with inferred from direct assay <newline> protein complex ; GO:0043234 | inferred from physical interaction with Su(H) <newline> integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR010660, InterPro:IPR011656","transmembrane receptor activity ; GO:0004888 | traceable author statement <newline> receptor activity ; GO:0004872 | non-traceable author statement <newline> transcription activator activity ; GO:0016563 | non-traceable author statement <newline> receptor activity ; GO:0004872 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with dx <newline> transmembrane receptor activity ; GO:0004888 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> protein binding ; GO:0005515 | inferred from physical interaction with shg <newline> transcription activator activity ; GO:0016563 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VVI3 <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9Y0H4 <newline> protein binding ; GO:0005515 | inferred from physical interaction with Su(H) <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097"]
[null,"FBgn0004854","BarH2","B-H2","The gene BarH2 is referred to in FlyBase by the symbol Dmel\\B-H2 (CG5488, FBgn0004854). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:17208614..17218195. It has the cytological map location 16A1. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity; DNA binding; transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: sensory organ boundary specification; compound eye photoreceptor cell differentiation; leg disc proximal/distal pattern formation; eye-antennal disc morphogenesis; eye pigment granule organization; bristle morphogenesis. 8 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; thoracic segment; metatarsus; organ system; peripheral nervous system; appendage segment; adult mesothoracic segment; nervous system; eipithelial furrow; external compound sense organ. It has one annotated transcript and one annotated polypeptide.","sensory organ boundary specification ; GO:0008052 | inferred from mutant phenotype <newline> eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype <newline> leg disc proximal/distal pattern formation ; GO:0007479 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970","nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR017970","specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001356"]
[null,"FBgn0005771","no ocelli","noc","The gene no ocelli is referred to in FlyBase by the symbol Dmel\\noc (CG4491, FBgn0005771). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:14490862..14494019. It has the cytological map location 35B2. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior; eye-antennal disc development; cell proliferation; open tracheal system development. 55 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: peripheral nervous system; nervous system; organ system; adult segment; embryonic/larval tracheal system; integumentary plate; adult mesothoracic segment; embryonic dorsal branch; adult brain; adult external prothorax; embryonic ganglionic branch; postalar bristle. It has one annotated transcript and one annotated polypeptide.","regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from genetic interaction with elB <newline> eye-antennal disc development ; GO:0035214 | inferred from genetic interaction with elB <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0010300","brain tumor","brat","The gene brain tumor is referred to in FlyBase by the symbol Dmel\\brat (CG10719, FBgn0010300). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:19133806..19172572. It has the cytological map location 37C1-37C6. There is experimental evidence that it has the molecular function</span>: protein binding; translation repressor activity. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; cell division; cellular macromolecule metabolic process; stem cell differentiation; regulation of biological process; transport; ncRNA metabolic process; neuroblast fate commitment; regionalization; biopolymer biosynthetic process; reproductive process in a multicellular organism; regulation of neurogenesis; neuron differentiation; regulation of metabolic process. 100 alleles are reported. The phenotypes of these alleles are annotated with: eye; neuron; 1st posterior cell; embryonic abdomen; adult thorax; embryonic epidermis; imaginal disc; embryonic/larval brain; ganglion mother cell; embryonic abdominal segment. It has 3 annotated transcripts and 3 annotated polypeptides.","rRNA metabolic process ; GO:0016072 | inferred from mutant phenotype <newline> rRNA transcription ; GO:0009303 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype <newline> brain development ; GO:0007420 | inferred from mutant phenotype <newline> asymmetric cell division ; GO:0008356 | inferred from mutant phenotype <newline> negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype <newline> ganglion mother cell fate determination ; GO:0007402 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | non-traceable author statement <newline> regulation of translation ; GO:0006417 | inferred from mutant phenotype <newline> regulation of translation ; GO:0006417 | traceable author statement <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> asymmetric neuroblast division resulting in ganglion mother cell formation ; GO:0055060 | inferred from mutant phenotype <newline> neuron differentiation ; GO:0030182 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay <newline> basal cortex ; GO:0045180 | colocalizes_with inferred from direct assay <newline> apical cortex ; GO:0045179 | colocalizes_with inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with nos <newline> translation repressor activity ; GO:0030371 | inferred from mutant phenotype <newline> translation regulator activity ; GO:0045182 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with 4EHP <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000315"]
[null,"FBgn0011591","fringe","fng","The gene fringe is referred to in FlyBase by the symbol Dmel\\fng (CG10580, FBgn0011591). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20918983..20942609. It has the cytological map location 78A1. There is experimental evidence that it has the molecular function</span>: UDP-glycosyltransferase activity; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity; acetylglucosaminyltransferase activity. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; organ morphogenesis; regulation of biological process; leg morphogenesis; sensory organ development; leg segmentation; biopolymer modification; hexose metabolic process; regionalization; appendage development; compound eye development. 66 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; female germline cyst; late extended germ band embryo; nervous system; ectoderm derivative; external compound sense organ; primordium. It has one annotated transcript and one annotated polypeptide.","imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> dorsal/ventral pattern formation, imaginal disc ; GO:0007450 | inferred from direct assay <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from direct assay <newline> leg joint morphogenesis ; GO:0035111 | inferred from mutant phenotype <newline> leg segmentation ; GO:0035286 | inferred from mutant phenotype <newline> Notch signaling pathway ; GO:0007219 | inferred from direct assay <newline> fucose metabolic process ; GO:0006004 | inferred from direct assay <newline> germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype <newline> regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype <newline> positive regulation of Notch signaling pathway ; GO:0045747 | non-traceable author statement <newline> Notch signaling pathway ; GO:0007219 | traceable author statement <newline> dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | traceable author statement <newline> regulation of Notch signaling pathway ; GO:0008593 | traceable author statement <newline> negative regulation of Notch signaling pathway ; GO:0045746 | non-traceable author statement <newline> regulation of Notch signaling pathway ; GO:0008593 | non-traceable author statement <newline> cell fate specification ; GO:0001708 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from direct assay <newline> oogenesis ; GO:0048477 | traceable author statement <newline> regulation of Notch signaling pathway ; GO:0008593 | inferred from direct assay <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> protein amino acid O-linked glycosylation ; GO:0006493 | inferred from mutant phenotype <newline> fucose metabolic process ; GO:0006004 | inferred from mutant phenotype","Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> Golgi apparatus ; GO:0005794 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | non-traceable author statement <newline> Golgi stack ; GO:0005795 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> Golgi apparatus ; GO:0005794 | traceable author statement <newline> integral to Golgi membrane ; GO:0030173 | inferred from electronic annotation with InterPro:IPR017374","UDP-glycosyltransferase activity ; GO:0008194 | inferred from direct assay <newline> acetylglucosaminyltransferase activity ; GO:0008375 | inferred from direct assay <newline> acetylglucosaminyltransferase activity ; GO:0008375 | non-traceable author statement <newline> acetylglucosaminyltransferase activity ; GO:0008375 | traceable author statement <newline> O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity ; GO:0033829 | inferred from direct assay"]
[null,"FBgn0013263","Trithorax-like","Trl","The gene Trithorax-like is referred to in FlyBase by the symbol Dmel\\Trl (CG33261, FBgn0013263). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14741029..14754149. It has the cytological map location 70F4. There is experimental evidence that it has the molecular function</span>: protein binding; specific RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: cellular process; dosage compensation; nuclear division; syncytial blastoderm mitotic cell cycle; imaginal disc-derived wing morphogenesis; protein oligomerization. 68 alleles are reported. The phenotypes of these alleles are annotated with: eye; abdominal segment 6; egg; sex comb; micropyle; wing; imaginal disc; egg chamber; chromatin; denticle belt. It has 9 annotated transcripts and 9 annotated polypeptides.","nuclear division ; GO:0000280 | inferred from mutant phenotype <newline> syncytial blastoderm mitotic cell cycle ; GO:0035186 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | non-traceable author statement <newline> chromatin organization ; GO:0006325 | non-traceable author statement <newline> dosage compensation ; GO:0007549 | inferred from mutant phenotype <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> positive regulation of transcription, DNA-dependent ; GO:0045893 | traceable author statement <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> protein oligomerization ; GO:0051259 | inferred from direct assay","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> centromeric heterochromatin ; GO:0005721 | inferred from direct assay AND traceable author statement <newline> chromatin ; GO:0000785 | non-traceable author statement","DNA binding ; GO:0003677 | non-traceable author statement <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from mutant phenotype <newline> protein binding ; GO:0005515 | inferred from physical interaction with Ssrp <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P17789 <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P41046 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0015296","SHC-adaptor protein","Shc","The gene SHC-adaptor protein is referred to in FlyBase by the symbol Dmel\\Shc (CG3715, FBgn0015296). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9420100..9421779. It has the cytological map location 67B5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: torso signaling pathway; epidermal growth factor receptor signaling pathway; tracheal outgrowth, open tracheal system. 8 alleles are reported. The phenotypes of these alleles are annotated with: eye; ommatidium. It has one annotated transcript and one annotated polypeptide.","epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from genetic interaction with Egfr <newline> torso signaling pathway ; GO:0008293 | inferred from genetic interaction with tor <newline> tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype <newline> intracellular signaling pathway ; GO:0023034 | inferred from electronic annotation with InterPro:IPR006019","-","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000980"]
[null,"FBgn0015790","Rab-protein 11","Rab11","The gene Rab-protein 11 is referred to in FlyBase by the symbol Dmel\\Rab11 (CG5771, FBgn0015790). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16937129..16941877. It has the cytological map location 93B12-93B13. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. There is experimental evidence for 18 unique biological process</span> terms, many of which group under: anatomical structure development; sensory organ development; reproductive process in a multicellular organism; cell division; organ morphogenesis; cell cycle; organelle organization; transport; regulation of cellular component organization; contractile ring contraction involved in cytokinesis during cell cycle; immune response; synaptic transmission; regulation of developmental process; vesicle fusion; actin filament-based process. 44 alleles are reported. The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: peripheral nervous system; nervous system; external compound sense organ; adult segment; cytoplasmic part; organ system; adult mesothoracic segment; intracellular membrane-bounded organelle; spindle; acroblast; rhabdomere; contractile ring; egg; cell division site; imaginal precursor; syncytial blastoderm embryo; garland cell; late extended germ band embryo. It has 2 annotated transcripts and 2 annotated polypeptides.","regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype <newline> endocytosis ; GO:0006897 | inferred from mutant phenotype <newline> oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype <newline> actin cytoskeleton reorganization ; GO:0031532 | inferred from mutant phenotype <newline> rhabdomere development ; GO:0042052 | inferred from mutant phenotype <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> cellularization ; GO:0007349 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from genetic interaction with bchs <newline> bristle development ; GO:0022416 | inferred from mutant phenotype <newline> regulation of synapse organization ; GO:0050807 | inferred from mutant phenotype <newline> endocytosis ; GO:0006897 | inferred from direct assay <newline> sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype <newline> spermatocyte division ; GO:0048137 | inferred from mutant phenotype <newline> contractile ring contraction involved in cell cycle cytokinesis ; GO:0000916 | inferred from mutant phenotype <newline> Golgi vesicle fusion to target membrane ; GO:0048210 | inferred from mutant phenotype <newline> small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579 <newline> protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR003579","trans-Golgi network transport vesicle ; GO:0030140 | inferred from direct assay <newline> terminal button ; GO:0043195 | inferred from direct assay <newline> centrosome ; GO:0005813 | colocalizes_with inferred from direct assay <newline> endosome ; GO:0005768 | inferred from direct assay <newline> lipid particle ; GO:0005811 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> vesicle ; GO:0031982 | inferred from direct assay <newline> cell pole ; GO:0060187 | inferred from direct assay <newline> cleavage furrow ; GO:0032154 | inferred from direct assay <newline> Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> spindle envelope ; GO:0070732 | inferred from direct assay <newline> nuclear envelope ; GO:0005635 | inferred from direct assay <newline> perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay","GTPase activity ; GO:0003924 | inferred from sequence or structural similarity <newline> GTP binding ; GO:0005525 | non-traceable author statement <newline> GTPase activity ; GO:0003924 | non-traceable author statement <newline> GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225"]
[null,"FBgn0015919","caupolican","caup","The gene caupolican is referred to in FlyBase by the symbol Dmel\\caup (CG10605, FBgn0015919). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:12603226..12614908. It has the cytological map location 69D1. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity, enhancer binding; transcription activator activity. There is experimental evidence that it is involved in the biological process</span>: imaginal disc-derived wing vein specification; compound eye morphogenesis; phagocytosis, engulfment. 13 alleles are reported. The phenotypes of these alleles are annotated with: mesothoracic segment; eye; macrochaeta; notopleural suture; vertical bristle; wing; microchaeta; ommatidium; scutellum. It has one annotated transcript and one annotated polypeptide.","equator specification ; GO:0045317 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from genetic interaction with ara <newline> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from sequence or structural similarity with ara","nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with HGNC_gene:PBX1; HGNC:8632; OMIM:176310","specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> transcription regulator activity ; GO:0030528 | non-traceable author statement <newline> RNA polymerase II transcription factor activity, enhancer binding ; GO:0003705 | inferred from sequence or structural similarity with ara <newline> transcription activator activity ; GO:0016563 | inferred from sequence or structural similarity with ara"]
[null,"FBgn0016797","frizzled 2","fz2","The gene frizzled 2 is referred to in FlyBase by the symbol Dmel\\fz2 (CG9739, FBgn0016797). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19135998..19228191. It has the cytological map location 75F9-76A3. There is experimental evidence that it has the molecular function</span>: Wnt receptor activity; protein binding; PDZ domain binding; Wnt-protein binding. There is experimental evidence that it is involved in the biological process</span>: female gonad development; cellular component movement; imaginal disc-derived wing margin morphogenesis; receptor-mediated endocytosis; bristle morphogenesis; Wnt receptor signaling pathway; axon extension; salivary gland morphogenesis; Wnt receptor signaling pathway, calcium modulating pathway; synapse organization. 112 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; adult segment; nervous system; adult mesothoracic segment; external compound sense organ; peripheral nervous system; cell component; cuticle; t-bar; embryonic neuron; postsynaptic membrane; neuromuscular junction. It has 4 annotated transcripts and 4 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from direct assay <newline> establishment or maintenance of cell polarity ; GO:0007163 | inferred from sequence or structural similarity <newline> Wnt receptor signaling pathway, calcium modulating pathway ; GO:0007223 | inferred from direct assay <newline> cellular component movement ; GO:0006928 | inferred from mutant phenotype <newline> female gonad development ; GO:0008585 | inferred from mutant phenotype <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> receptor-mediated endocytosis ; GO:0006898 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from sequence or structural similarity <newline> Wnt receptor signaling pathway ; GO:0016055 | non-traceable author statement <newline> axon extension ; GO:0048675 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> synapse organization ; GO:0050808 | inferred from physical interaction with Grip <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype","integral to membrane ; GO:0016021 | non-traceable author statement <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> early endosome ; GO:0005769 | colocalizes_with inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> late endosome ; GO:0005770 | colocalizes_with inferred from direct assay","Wnt receptor activity ; GO:0042813 | inferred from direct assay <newline> Wnt-protein binding ; GO:0017147 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from direct assay <newline> transmembrane receptor activity ; GO:0004888 | inferred from sequence or structural similarity <newline> Wnt receptor activity ; GO:0042813 | non-traceable author statement <newline> PDZ domain binding ; GO:0030165 | inferred from physical interaction with Grip <newline> non-G-protein coupled 7TM receptor activity ; GO:0004926 | inferred from electronic annotation with InterPro:IPR000539"]
[null,"FBgn0023215","Mnt","Mnt","The gene Mnt is referred to in FlyBase by the symbol Dmel\\Mnt (CG13316, FBgn0023215). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3565834..3594813. It has the cytological map location 3E4-3E5. There is experimental evidence that it has the molecular function</span>: protein binding; sequence-specific DNA binding; transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription; regulation of cell cycle; negative regulation of cell growth; phagocytosis, engulfment. 32 alleles are reported. The phenotypes of these alleles are annotated with: eye; adult head; ommatidium; wing hair. It has 7 annotated transcripts and 7 annotated polypeptides.","regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with dm <newline> regulation of transcription ; GO:0045449 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> negative regulation of cell growth ; GO:0030308 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity <newline> nucleus ; GO:0005634 | inferred by curator from GO:0003700 <newline> nucleus ; GO:0005634 | inferred from direct assay","RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with dm <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity with UniProtKB:Q99583 <newline> protein binding ; GO:0005515 | inferred from physical interaction with Max <newline> sequence-specific DNA binding ; GO:0043565 | inferred from direct assay <newline> transcription repressor activity ; GO:0016564 | inferred from direct assay"]
[null,"FBgn0026576","-","CG5991","This gene is referred to in FlyBase by the symbol Dmel\\CG5991 (CG5991, FBgn0026576). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19876511..19879314. It has the cytological map location 95D10. Based on sequence similarity, it is predicted to have molecular function</span>: phosphatidylserine decarboxylase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: phospholipid biosynthetic process. 5 alleles are reported. The phenotypes of these alleles are annotated with: eye; tarsal segment. It has 3 annotated transcripts and 3 annotated polypeptides.","phospholipid biosynthetic process ; GO:0008654 | inferred from electronic annotation with InterPro:IPR003817, InterPro:IPR005221",null,"phosphatidylserine decarboxylase activity ; GO:0004609 | inferred from sequence or structural similarity with UniProtKB:P27465"]
[null,"FBgn0029504","Checkpoint suppressor homologue","CHES-1-like","The gene Checkpoint suppressor homologue is referred to in FlyBase by the symbol Dmel\\CHES-1-like (CG12690, FBgn0029504). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7577491..7598851. It has the cytological map location 7B6. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 29 alleles are reported. The phenotypes of these alleles are annotated with: eye; embryonic heart. It has 2 annotated transcripts and 2 annotated polypeptides.","regulation of transcription, DNA-dependent ; GO:0006355 | inferred from sequence or structural similarity with EMBL:Y11741 <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:Y11741","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:Y11741 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001766, InterPro:IPR018122"]
[null,"FBgn0036899","teyrha-meyrha","tey","The gene teyrha-meyrha is referred to in FlyBase by the symbol Dmel\\tey (CG8780, FBgn0036899). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19643902..19656763. It has the cytological map location 76B11-76C1. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotypes of these alleles are annotated with: eye; costal cell; distal costal vein; medial costal vein. It has 2 annotated transcripts and 2 annotated polypeptides.","-","-","-"]
[null,"FBgn0037645","-","CG11966","This gene is referred to in FlyBase by the symbol Dmel\\CG11966 (CG11966, FBgn0037645). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4777711..4788683. It has the cytological map location 85B8-85B9. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding; nucleic acid binding. The biological processes in which it is involved are not known. 14 alleles are reported. The phenotypes of these alleles are annotated with: ventral nerve cord commissure; eye; ventral nerve cord; ventral midline. It has one annotated transcript and one annotated polypeptide.","-","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087"]
[null,"FBgn0041604","dally-like","dlp","The gene dally-like is referred to in FlyBase by the symbol Dmel\\dlp (CG32146, FBgn0041604). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14625720..14664716. It has the cytological map location 70E5-70E7. It is reported to have molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; detection of light stimulus involved in visual perception; axon guidance; compound eye development; imaginal disc-derived wing margin morphogenesis; wing disc dorsal/ventral pattern formation; positive regulation of smoothened signaling pathway; Wnt receptor signaling pathway; regulation of imaginal disc growth; segment polarity determination. 39 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; peripheral nervous system; adult mesothoracic segment; external compound sense organ; organ system; nervous system; cuticle; lamina plexus; dorsal thoracic disc; compound cell cluster organ. It has 2 annotated transcripts and 2 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from genetic interaction with dally AND inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> decapentaplegic receptor signaling pathway ; GO:0008101 | non-traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | traceable author statement <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from expression pattern AND inferred from genetic interaction with wg <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> detection of light stimulus involved in visual perception ; GO:0050908 | inferred from mutant phenotype <newline> positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype <newline> regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype","extracellular region ; GO:0005576 | inferred from sequence or structural similarity <newline> proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR001863 <newline> membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001863","protein binding ; GO:0005515 | non-traceable author statement <newline> heparan sulfate proteoglycan binding ; GO:0043395 | inferred from electronic annotation with InterPro:IPR001863"]
[null,"FBgn0243512","puckered","puc","The gene puckered is referred to in FlyBase by the symbol Dmel\\puc (CG7850, FBgn0243512). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3931057..3948023. It has the cytological map location 84E12-84E11. There is experimental evidence that it has the molecular function</span>: JUN kinase phosphatase activity; phosphoprotein phosphatase activity. There is experimental evidence for 20 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; organ development; organ morphogenesis; regulation of biological process; actin filament-based process; ovarian follicle cell development; regulation of developmental process; response to stress; organelle organization. 54 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; egg; cuticle; peripheral nervous system; external compound sense organ; adult segment; nervous system; chorion; adult mesothoracic segment; cuticular specialization. It has one annotated transcript and one annotated polypeptide.","imaginal disc eversion ; GO:0007561 | inferred from mutant phenotype <newline> imaginal disc fusion ; GO:0046528 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> epidermis development ; GO:0008544 | inferred from mutant phenotype <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> JNK cascade ; GO:0007254 | non-traceable author statement <newline> suture of dorsal opening ; GO:0007396 | non-traceable author statement <newline> JNK cascade ; GO:0007254 | inferred from mutant phenotype <newline> actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype <newline> protein amino acid dephosphorylation ; GO:0006470 | inferred from direct assay AND inferred from sequence or structural similarity <newline> protein amino acid dephosphorylation ; GO:0006470 | non-traceable author statement <newline> JNK cascade ; GO:0007254 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> wound healing ; GO:0042060 | inferred from expression pattern <newline> negative regulation of JNK cascade ; GO:0046329 | traceable author statement <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> response to oxidative stress ; GO:0006979 | inferred from mutant phenotype <newline> wound healing ; GO:0042060 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> negative regulation of JNK cascade ; GO:0046329 | non-traceable author statement <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> micropyle formation ; GO:0046844 | inferred from mutant phenotype <newline> wound healing ; GO:0042060 | inferred from direct assay <newline> dorsal closure ; GO:0007391 | non-traceable author statement <newline> ommatidial rotation ; GO:0016318 | non-traceable author statement <newline> establishment of planar polarity ; GO:0001736 | non-traceable author statement <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Pvr <newline> regulation of G2/M transition of mitotic cell cycle ; GO:0010389 | inferred from mutant phenotype","Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay","MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | non-traceable author statement <newline> JUN kinase phosphatase activity ; GO:0008579 | inferred from mutant phenotype <newline> phosphoprotein phosphatase activity ; GO:0004721 | inferred from direct assay <newline> protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity <newline> protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from sequence or structural similarity <newline> JUN kinase phosphatase activity ; GO:0008579 | non-traceable author statement <newline> JUN kinase phosphatase activity ; GO:0008579 | traceable author statement <newline> protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement <newline> MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | traceable author statement <newline> protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130"]
[null,"FBgn0259176","bunched","bun","The gene bunched is referred to in FlyBase by the symbol Dmel\\bun (CG42281, FBgn0259176). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12456577..12546630. It has the cytological map location 33E5-33E9. Based on sequence similarity, it is predicted to have molecular function</span>: protein homodimerization activity. There is experimental evidence for 13 unique biological process</span> terms, many of which group under: regulation of biological process; anatomical structure development; reproductive process in a multicellular organism; regulation of developmental process; programmed cell death; ovarian follicle cell development; positive regulation of biological process; positive regulation of cell proliferation; regionalization; regulation of anatomical structure size; gland morphogenesis; regulation of apoptosis; negative regulation of Notch signaling pathway. 140 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: external compound sense organ; peripheral nervous system; adult segment; organ system; nervous system; female germline cyst; egg; chorion; thoracic segment; adult mesothoracic segment. It has 8 annotated transcripts and 8 annotated polypeptides.","decapentaplegic receptor signaling pathway ; GO:0008101 | inferred from genetic interaction with dpp <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype <newline> negative regulation of cell fate specification ; GO:0009996 | inferred from mutant phenotype <newline> ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype <newline> negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype <newline> cell fate determination ; GO:0001709 | non-traceable author statement <newline> dorsal appendage formation ; GO:0046843 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> compound eye development ; GO:0048749 | non-traceable author statement <newline> oogenesis ; GO:0048477 | non-traceable author statement <newline> positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype <newline> positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000580","cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | non-traceable author statement","protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000580"]
[null,"FBgn0259220","Darkener of apricot","Doa","The gene Darkener of apricot is referred to in FlyBase by the symbol Dmel\\Doa (CG42320, FBgn0259220). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:24713799..24748494. It has the cytological map location 98F1-98F2. There is experimental evidence that it has the molecular function</span>: protein serine/threonine kinase activity; protein kinase activity. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; regulation of biological process; programmed cell death; sensory organ development; biopolymer modification; reproductive developmental process; neuromuscular process; embryonic pattern specification; gland morphogenesis; locomotory behavior; organ morphogenesis; regulation of metabolic process. 56 alleles are reported. The phenotypes of these alleles are annotated with: female genitalia; eye; macrochaeta; female terminalia sensillum; ommatidium; pigment cell. It has 13 annotated transcripts and 13 annotated polypeptides.","central nervous system development ; GO:0007417 | non-traceable author statement <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | non-traceable author statement <newline> photoreceptor cell maintenance ; GO:0045494 | non-traceable author statement <newline> sex differentiation ; GO:0007548 | inferred from genetic interaction with tra2 AND inferred from genetic interaction with tra AND inferred from mutant phenotype <newline> MAPKKK cascade ; GO:0000165 | inferred from genetic interaction with rl AND inferred from genetic interaction with sev AND inferred from genetic interaction with sina AND inferred from genetic interaction with svp NOT <newline> compound eye photoreceptor development ; GO:0042051 | inferred from expression pattern AND inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> blastoderm segmentation ; GO:0007350 | non-traceable author statement <newline> bristle morphogenesis ; GO:0008407 | non-traceable author statement <newline> compound eye photoreceptor development ; GO:0042051 | non-traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> karyosome formation ; GO:0030717 | inferred from mutant phenotype <newline> regulation of alternative nuclear mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | non-traceable author statement <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> protein amino acid autophosphorylation ; GO:0046777 | inferred from direct assay <newline> brain morphogenesis ; GO:0048854 | inferred from mutant phenotype <newline> startle response ; GO:0001964 | inferred from mutant phenotype <newline> locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype","nucleus ; GO:0005634 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred by curator from GO:0000381 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay <newline> protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with NCBI_NP:003984 <newline> protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement <newline> protein serine/threonine/tyrosine kinase activity ; GO:0004712 | non-traceable author statement <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0261648","spalt major","salm","The gene spalt major is referred to in FlyBase by the symbol Dmel\\salm (CG6464, FBgn0261648). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:11434311..11445603. It has the cytological map location 32F1-32F2. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity; transcription regulator activity. There is experimental evidence that it is involved in the biological process</span>: oenocyte development; notum cell fate specification; R8 cell differentiation; sensory organ development; compound eye photoreceptor cell differentiation; spiracle morphogenesis, open tracheal system; R7 cell differentiation; open tracheal system development; antennal joint development. 28 alleles are reported. The phenotypes of these alleles are annotated with 52 unique terms, many of which group under: adult segment; adult mesothoracic segment; peripheral nervous system; organ system; nervous system; embryonic/larval tracheal system; embryonic nervous system; antennal segment; appendage segment; embryonic segment. It has one annotated transcript and one annotated polypeptide.","spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> negative regulation of transcription ; GO:0016481 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> oenocyte development ; GO:0007438 | inferred from mutant phenotype <newline> antennal joint development ; GO:0048098 | inferred from mutant phenotype <newline> R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype <newline> R8 cell differentiation ; GO:0045465 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | non-traceable author statement <newline> epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement <newline> R8 cell differentiation ; GO:0045465 | non-traceable author statement <newline> segment specification ; GO:0007379 | non-traceable author statement <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype <newline> notum cell fate specification ; GO:0035310 | inferred from mutant phenotype","nucleus ; GO:0005634 | non-traceable author statement <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> transcription regulator activity ; GO:0030528 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087"]
[null,"FBgn0262127","kibra ortholog","kibra","The gene kibra ortholog is referred to in FlyBase by the symbol Dmel\\kibra (CG33967, FBgn0262127). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: regulation of hippo signaling pathway; compound eye morphogenesis. 46 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; eye. It has one annotated transcript and one annotated polypeptide. Protein features are: C2 calcium-dependent membrane targeting; C2 calcium/lipid-binding domain, CaLB; WW/Rsp5/WWP. Gene sequence location is 3R:10524252..10549978.","regulation of hippo signaling cascade ; GO:0035330 | inferred from genetic interaction with hpo inferred from genetic interaction with Mer inferred from genetic interaction with ex <newline> regulation of hippo signaling cascade ; GO:0035330 | inferred from genetic interaction with hpo inferred from genetic interaction with yki <newline> regulation of hippo signaling cascade ; GO:0035330 | inferred from genetic interaction with ex inferred from genetic interaction with Mer inferred from genetic interaction with sav inferred from genetic interaction with hpo <newline> compound eye morphogenesis ; GO:0001745 | inferred from genetic interaction with crb","apical part of cell ; GO:0045177 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with Mer inferred from physical interaction with ex inferred from physical interaction with wts <newline> protein binding ; GO:0005515 | inferred from physical interaction with Mer <newline> protein binding ; GO:0005515 | inferred from physical interaction with sav"]
[null,"FBgn0035142","homeodomain interacting protein kinase","hipk","The gene homeodomain interacting protein kinase is referred to in FlyBase by the symbol Dmel\\hipk (CG17090, FBgn0035142). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: beta-catenin binding; transcription factor binding; protein serine/threonine kinase activity; protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of Wnt receptor signaling pathway; compound eye development; imaginal disc-derived wing margin morphogenesis; protein stabilization; protein amino acid phosphorylation; imaginal disc-derived wing vein morphogenesis; positive regulation of Notch signaling pathway. 33 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; eye disc; eye; intersegmental nerve; eye photoreceptor cell. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain. Gene sequence location is 3L:543070..576065.","protein phosphorylation ; GO:0006468 | non-traceable author statement <newline> positive regulation of Notch signaling pathway ; GO:0045747 | inferred from genetic interaction with Dl inferred from genetic interaction with N inferred from genetic interaction with gro inferred from genetic interaction with H <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> positive regulation of Wnt receptor signaling pathway ; GO:0030177 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> protein stabilization ; GO:0050821 | inferred from mutant phenotype <newline> protein phosphorylation ; GO:0006468 | inferred from direct assay","-","protein kinase activity ; GO:0004672 | non-traceable author statement <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with SGD_LOCUS:YAK1; SGD:S0003677 <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay <newline> beta-catenin binding ; GO:0008013 | inferred from physical interaction with arm <newline> transcription factor binding ; GO:0008134 | inferred from physical interaction with pan <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0262582","capicua","cic","The gene capicua is referred to in FlyBase by the symbol Dmel\\cic (CG43122, FBgn0262582). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: wing disc dorsal/ventral pattern formation; eye morphogenesis; imaginal disc-derived wing vein specification; dorsal appendage formation; negative regulation of cell growth. 42 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; anatomical structure; adult segment; thoracic segment; acellular anatomical structure; abdominal segment; adult; egg; larval integumentary system; cell part; external compound sense organ. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Armadillo-like helical; High mobility group, HMG1/HMG2; High mobility group, superfamily. Gene sequence location is 3R:16078492..16128194.","negative regulation of transcription ; GO:0016481 | traceable author statement <newline> embryonic development via the syncytial blastoderm ; GO:0001700 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> eye morphogenesis ; GO:0048592 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> negative regulation of cell growth ; GO:0030308 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:AB014474; protein_id:BAA28604.1 <newline> nucleus ; GO:0005634 | non-traceable author statement","sequence-specific DNA binding transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:AB014474; protein_id:BAA28604.1 <newline> transcription cofactor activity ; GO:0003712 | non-traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription regulator activity ; GO:0030528 | non-traceable author statement <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000910"]
[null,"FBgn0087007","big bang","bbg","The gene big bang is referred to in FlyBase by the symbol Dmel\\bbg (CG42230, FBgn0087007). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: imaginal disc development. 39 alleles are reported. The phenotype of these alleles is annotated with: imaginal disc. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: PDZ/DHR/GLGF. Gene sequence location is 3L:14405921..14506348.","imaginal disc development ; GO:0007444 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay","-"]
[null,"FBgn0010501","Death caspase-1","Dcp-1","The gene Death caspase-1 is referred to in FlyBase by the symbol Dmel\\Dcp-1 (CG5370, FBgn0010501). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: cysteine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: apoptosis; ovarian nurse cell to oocyte transport; cleavage of lamin; actin cytoskeleton organization; embryonic development; autophagic cell death; developmental programmed cell death; salivary gland cell autophagic cell death. 38 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; eye; embryonic/larval digestive system; gonad; trachea; imaginal disc; outer photoreceptor cell; egg chamber; melanotic mass; pigment cell. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase C14, ICE, catalytic subunit p20; Peptidase C14, ICE, catalytic subunit p20, active site; Peptidase C14, caspase catalytic; Peptidase C14, caspase non-catalytic subunit p10; Peptidase C14, caspase precursor p45; Peptidase C14, caspase precursor p45, core. Gene sequence location is 2R:19438838..19441079.","apoptosis ; GO:0006915 | inferred from direct assay <newline> embryo development ; GO:0009790 | inferred from mutant phenotype <newline> actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype <newline> cleavage of lamin ; GO:0006922 | inferred from mutant phenotype <newline> ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype <newline> actin filament organization ; GO:0007015 | traceable author statement <newline> cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | traceable author statement <newline> nurse cell apoptosis ; GO:0045476 | traceable author statement <newline> apoptosis ; GO:0006915 | non-traceable author statement <newline> apoptosis ; GO:0006915 | traceable author statement <newline> proteolysis ; GO:0006508 | traceable author statement <newline> multicellular organismal development ; GO:0007275 | traceable author statement <newline> ovarian nurse cell to oocyte transport ; GO:0007300 | traceable author statement <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> apoptosis ; GO:0006915 | inferred from mutant phenotype <newline> developmental programmed cell death ; GO:0010623 | inferred from mutant phenotype","caspase complex ; GO:0008303 | non-traceable author statement","cysteine-type endopeptidase activity ; GO:0004197 | inferred from direct assay <newline> cysteine-type endopeptidase activity ; GO:0004197 | inferred from direct assay AND inferred from sequence or structural similarity <newline> cysteine-type endopeptidase activity ; GO:0004197 | traceable author statement <newline> cysteine-type endopeptidase activity ; GO:0004197 | non-traceable author statement <newline> cysteine-type endopeptidase activity ; GO:0004197 | inferred from sequence or structural similarity"]
[null,"FBgn0004655","wings apart-like","wapl","The gene wings apart-like is referred to in FlyBase by the symbol Dmel\\wapl (CG3707, FBgn0004655). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. There is experimental evidence that it is involved in the biological process</span>: female meiosis chromosome segregation; sister chromatid cohesion. 37 alleles are reported. The phenotypes of these alleles are annotated with: eye; wing; tergite; wing vein. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Armadillo-like helical; Armadillo-type fold; Wings apart-like protein; Wings apart-like, metazoan/plants. Gene sequence location is X:2044135..2053016.","sister chromatid cohesion ; GO:0007062 | inferred from mutant phenotype <newline> female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype","cellular_component ; GO:0005575 | no biological data available","binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR011989, InterPro:IPR016024"]
[]
["Genital discs/ ovarian development"]
[null,"FBgn0000504","doublesex","dsx","The gene doublesex is referred to in FlyBase by the symbol Dmel\\dsx (CG11094, FBgn0000504). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3750045..3793130. It has the cytological map location 84E5-84E6. There is experimental evidence that it has the molecular function</span>: protein binding; protein homodimerization activity. There is experimental evidence that it is involved in the biological process</span>: imaginal disc-derived female genitalia development; imaginal disc-derived male genitalia development; genital disc development. 116 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; adult segment; region of integument; adult; peripheral nervous system; imaginal precursor; nervous system; hub cell; larval abdominal segment 8; male accessory gland; female genitalia; external compound sense organ; female germline cyst. It has 3 annotated transcripts and 3 annotated polypeptides.","imaginal disc-derived female genitalia development ; GO:0007486 | inferred from genetic interaction with tra2 <newline> genital disc development ; GO:0035215 | inferred from mutant phenotype <newline> imaginal disc-derived male genitalia development ; GO:0007485 | inferred from genetic interaction with tra2 <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | non-traceable author statement <newline> positive regulation of transcription, DNA-dependent ; GO:0045893 | non-traceable author statement <newline> female somatic sex determination ; GO:0019101 | traceable author statement <newline> spermatogenesis ; GO:0007283 | non-traceable author statement <newline> sex determination ; GO:0007530 | non-traceable author statement <newline> somatic sex determination ; GO:0018993 | non-traceable author statement <newline> transcription from RNA polymerase II promoter ; GO:0006366 | non-traceable author statement <newline> sex differentiation ; GO:0007548 | non-traceable author statement <newline> courtship behavior ; GO:0007619 | non-traceable author statement <newline> male courtship behavior, veined wing generated song production ; GO:0045433 | non-traceable author statement <newline> female somatic sex determination ; GO:0019101 | non-traceable author statement <newline> male courtship behavior, veined wing generated song production ; GO:0045433 | traceable author statement <newline> male somatic sex determination ; GO:0019102 | non-traceable author statement <newline> female analia development ; GO:0045497 | non-traceable author statement <newline> imaginal disc-derived female genitalia development ; GO:0007486 | non-traceable author statement <newline> genital disc development ; GO:0035215 | traceable author statement <newline> genital disc sexually dimorphic development ; GO:0035263 | traceable author statement <newline> male analia development ; GO:0045496 | non-traceable author statement <newline> imaginal disc-derived male genitalia development ; GO:0007485 | non-traceable author statement <newline> sex comb development ; GO:0045498 | traceable author statement <newline> female sex differentiation ; GO:0046660 | traceable author statement <newline> sex-specific pigmentation ; GO:0048071 | traceable author statement <newline> central nervous system development ; GO:0007417 | traceable author statement <newline> sex differentiation ; GO:0007548 | traceable author statement <newline> sex-specific pigmentation ; GO:0048071 | non-traceable author statement <newline> genital disc morphogenesis ; GO:0007483 | traceable author statement <newline> negative regulation of developmental pigmentation ; GO:0048086 | traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | traceable author statement <newline> regulation of imaginal disc growth ; GO:0045570 | traceable author statement <newline> somatic sex determination ; GO:0018993 | traceable author statement <newline> behavior ; GO:0007610 | traceable author statement <newline> sex determination ; GO:0007530 | traceable author statement <newline> male sex differentiation ; GO:0046661 | traceable author statement <newline> nuclear mRNA splicing, via spliceosome ; GO:0000398 | traceable author statement <newline> regulation of transcription ; GO:0045449 | traceable author statement <newline> male courtship behavior ; GO:0008049 | traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001275","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:AF130728; protein_id:AAD40474.1","specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from sequence or structural similarity with EMBL:AF130728; protein_id:AAD40474.1 <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | non-traceable author statement <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | traceable author statement <newline> DNA binding ; GO:0003677 | traceable author statement <newline> mRNA binding ; GO:0003729 | non-traceable author statement <newline> transcription regulator activity ; GO:0030528 | traceable author statement <newline> protein homodimerization activity ; GO:0042803 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with ix <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001275"]
[null,"FBgn0001404","egghead","egh","The gene egghead is referred to in FlyBase by the symbol Dmel\\egh (CG9659, FBgn0001404). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2482534..2492638. It has the cytological map location 3A6. There is experimental evidence that it has the molecular function</span>: beta-1,4-mannosyltransferase activity. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: reproductive process in a multicellular organism; anatomical structure development; multicellular organism reproduction; ovarian follicle cell development; cellular component movement; organ morphogenesis; gamete generation; transport; regulation of response to stimulus; cell fate commitment; establishment or maintenance of polarity of follicular epithelium. 60 alleles are reported. The phenotypes of these alleles are annotated with 28 unique terms, many of which group under: organ system; adult segment; nervous system; multi-cell-component structure; female germline cyst; adult; peripheral nervous system; larval head segment; adult brain; egg; lamina plexus; embryonic nervous system; external compound sense organ. It has 2 annotated transcripts and 2 annotated polypeptides.","border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype <newline> ovarian follicle cell-cell adhesion ; GO:0007299 | inferred from mutant phenotype <newline> maintenance of polarity of follicular epithelium ; GO:0042248 | inferred from mutant phenotype <newline> morphogenesis of follicular epithelium ; GO:0016333 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> cell fate commitment ; GO:0045165 | inferred from mutant phenotype <newline> germ cell development ; GO:0007281 | inferred from mutant phenotype <newline> oocyte localization during germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype <newline> oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype <newline> optic lobe placode formation ; GO:0001744 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype <newline> regulation of oviposition ; GO:0046662 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | traceable author statement <newline> dsRNA transport ; GO:0033227 | inferred from mutant phenotype","integral to plasma membrane ; GO:0005887 | non-traceable author statement","beta-1,4-mannosyltransferase activity ; GO:0019187 | inferred from direct assay"]
[null,"FBgn0003401","shutdown","shu","The gene shutdown is referred to in FlyBase by the symbol Dmel\\shu (CG4735, FBgn0003401). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19728984..19730802. It has the cytological map location 60A3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. There is experimental evidence that it is involved in the biological process</span>: oogenesis. 9 alleles are reported. The phenotypes of these alleles are annotated with: ovariole; nurse follicle cell; egg; oocyte; egg chamber; dorsal appendage. It has one annotated transcript and one annotated polypeptide.","oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR001179","cytoplasm ; GO:0005737 | inferred from direct assay","binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR011990"]
[null,"FBgn0003502","Btk family kinase at 29A","Btk29A","The gene Btk family kinase at 29A is referred to in FlyBase by the symbol Dmel\\Btk29A (CG8049, FBgn0003502). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:8259504..8301072. It has the cytological map location 29A1-29A3. There is experimental evidence that it has the molecular function</span>: protein tyrosine kinase activity. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; ovarian nurse cell to oocyte transport; organelle organization; regulation of cellular component organization; gland morphogenesis; learning; determination of adult lifespan; cell cycle; actin filament-based process; multicellular organism reproduction. 48 alleles are reported. The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; cephalopharyngeal skeleton; female germline cyst; cuticle; integumentary specialisation; region of integument; embryonic foregut; adult; taenidial fold; mouthpart; actin cytoskeleton; egg; spiracle. It has 6 annotated transcripts and 6 annotated polypeptides.","protein amino acid phosphorylation ; GO:0006468 | inferred from sequence or structural similarity with UniProtKB:Q06187 <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> female germline ring canal formation ; GO:0007301 | inferred from mutant phenotype <newline> female germline ring canal formation ; GO:0007301 | inferred from expression pattern <newline> determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> imaginal disc-derived male genitalia development ; GO:0007485 | inferred from direct assay AND inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> cellularization ; GO:0007349 | inferred from mutant phenotype <newline> actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype <newline> karyosome formation ; GO:0030717 | inferred from mutant phenotype <newline> ovarian nurse cell to oocyte transport ; GO:0007300 | inferred from mutant phenotype <newline> ovarian fusome organization ; GO:0030723 | inferred from mutant phenotype <newline> DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype <newline> regulation of actin filament polymerization ; GO:0030833 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> courtship behavior ; GO:0007619 | non-traceable author statement <newline> JNK cascade ; GO:0007254 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> sensitization ; GO:0046960 | inferred from mutant phenotype <newline> intracellular signaling pathway ; GO:0023034 | inferred from electronic annotation with InterPro:IPR001562","cytoplasm ; GO:0005737 | inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> germline ring canal ; GO:0045172 | inferred from direct assay <newline> germline ring canal ; GO:0045172 | traceable author statement","protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity with UniProtKB:Q06187 <newline> protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay <newline> protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement <newline> protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity with UniProtKB:P42680 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR017441 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000980, InterPro:IPR020685"]
[null,"FBgn0011236","ken and barbie","ken","The gene ken and barbie is referred to in FlyBase by the symbol Dmel\\ken (CG5575, FBgn0011236). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19757798..19764965. It has the cytological map location 60A6-60A7. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity; protein binding; nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: imaginal disc-derived female genitalia development; female analia development; male analia development; insemination; imaginal disc-derived male genitalia development; regulation of JAK-STAT cascade; phagocytosis, engulfment. 28 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; region of integument; adult; adult segment; antennal segment; embryonic/larval tracheal system; larval abdominal segment; female genitalia; spiracle; vulva; imaginal precursor; integumentary specialisation. It has one annotated transcript and one annotated polypeptide.","copulation ; GO:0007620 | non-traceable author statement <newline> insemination ; GO:0007320 | inferred from mutant phenotype <newline> female analia development ; GO:0045497 | inferred from mutant phenotype <newline> imaginal disc-derived female genitalia development ; GO:0007486 | inferred from mutant phenotype <newline> male analia development ; GO:0045496 | inferred from mutant phenotype <newline> imaginal disc-derived male genitalia development ; GO:0007485 | inferred from mutant phenotype <newline> regulation of JAK-STAT cascade ; GO:0046425 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with InterPro:IPR007087","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity <newline> nucleic acid binding ; GO:0003676 | inferred from sequence or structural similarity with InterPro:IPR007087 <newline> protein binding ; GO:0005515 | inferred from sequence or structural similarity with InterPro:IPR000210 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0085443","sprint","spri","The gene sprint is referred to in FlyBase by the symbol Dmel\\spri (CG34414, FBgn0085443). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:10384098..10479056. It has the cytological map location 9D2-9D3. Based on sequence similarity, it is predicted to have molecular function</span>: Ras GTPase binding. There is experimental evidence that it is involved in the biological process</span>: border follicle cell migration. 48 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides.","border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Cbl inferred from genetic interaction with Egfr inferred from genetic interaction with Pvr <newline> endocytosis ; GO:0006897 | inferred from sequence or structural similarity with UniProtKB:Q8TB24 <newline> signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000159","cellular_component ; GO:0005575 | no biological data available","Ras GTPase binding ; GO:0017016 | inferred from sequence or structural similarity <newline> Ras GTPase binding ; GO:0017016 | inferred from sequence or structural similarity with EMBL:U80076 <newline> Ras GTPase binding ; GO:0017016 | inferred from sequence or structural similarity with UniProtKB:Q8TB24"]
[null,"FBgn0086676","spinster","spin","The gene spinster is referred to in FlyBase by the symbol Dmel\\spin (CG8428, FBgn0086676). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12012488..12025743. It has the cytological map location 52E6-52E. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: endosome to lysosome transport; regulation of programmed cell death; endocytosis; locomotion; larval central nervous system remodeling; synaptic vesicle endocytosis; regulation of nurse cell apoptosis; oogenesis; regulation of synaptic growth at neuromuscular junction; regulation of female receptivity. 63 alleles are reported. The phenotypes of these alleles are annotated with: embryonic head; retina; medulla; adult central nervous system; neuromuscular junction; embryonic peripheral nervous system; embryonic central nervous system; egg chamber; endosome; adult brain. It has 5 annotated transcripts and 5 annotated polypeptides.","regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype <newline> larval central nervous system remodeling ; GO:0035193 | inferred from mutant phenotype <newline> regulation of female receptivity ; GO:0045924 | inferred from mutant phenotype <newline> regulation of nurse cell apoptosis ; GO:0045477 | inferred from mutant phenotype <newline> regulation of programmed cell death ; GO:0043067 | inferred from mutant phenotype <newline> courtship behavior ; GO:0007619 | non-traceable author statement <newline> programmed cell death ; GO:0012501 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> locomotion ; GO:0040011 | inferred from mutant phenotype <newline> synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype <newline> endosome to lysosome transport ; GO:0008333 | inferred from mutant phenotype <newline> endocytosis ; GO:0006897 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701","plasma membrane ; GO:0005886 | non-traceable author statement","-"]
[null,"FBgn0243512","puckered","puc","The gene puckered is referred to in FlyBase by the symbol Dmel\\puc (CG7850, FBgn0243512). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3931057..3948023. It has the cytological map location 84E12-84E11. There is experimental evidence that it has the molecular function</span>: JUN kinase phosphatase activity; phosphoprotein phosphatase activity. There is experimental evidence for 20 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; organ development; organ morphogenesis; regulation of biological process; actin filament-based process; ovarian follicle cell development; regulation of developmental process; response to stress; organelle organization. 54 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; egg; cuticle; peripheral nervous system; external compound sense organ; adult segment; nervous system; chorion; adult mesothoracic segment; cuticular specialization. It has one annotated transcript and one annotated polypeptide.","imaginal disc eversion ; GO:0007561 | inferred from mutant phenotype <newline> imaginal disc fusion ; GO:0046528 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> epidermis development ; GO:0008544 | inferred from mutant phenotype <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> JNK cascade ; GO:0007254 | non-traceable author statement <newline> suture of dorsal opening ; GO:0007396 | non-traceable author statement <newline> JNK cascade ; GO:0007254 | inferred from mutant phenotype <newline> actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype <newline> protein amino acid dephosphorylation ; GO:0006470 | inferred from direct assay AND inferred from sequence or structural similarity <newline> protein amino acid dephosphorylation ; GO:0006470 | non-traceable author statement <newline> JNK cascade ; GO:0007254 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> wound healing ; GO:0042060 | inferred from expression pattern <newline> negative regulation of JNK cascade ; GO:0046329 | traceable author statement <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> response to oxidative stress ; GO:0006979 | inferred from mutant phenotype <newline> wound healing ; GO:0042060 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> negative regulation of JNK cascade ; GO:0046329 | non-traceable author statement <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> micropyle formation ; GO:0046844 | inferred from mutant phenotype <newline> wound healing ; GO:0042060 | inferred from direct assay <newline> dorsal closure ; GO:0007391 | non-traceable author statement <newline> ommatidial rotation ; GO:0016318 | non-traceable author statement <newline> establishment of planar polarity ; GO:0001736 | non-traceable author statement <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Pvr <newline> regulation of G2/M transition of mitotic cell cycle ; GO:0010389 | inferred from mutant phenotype","Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay","MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | non-traceable author statement <newline> JUN kinase phosphatase activity ; GO:0008579 | inferred from mutant phenotype <newline> phosphoprotein phosphatase activity ; GO:0004721 | inferred from direct assay <newline> protein tyrosine phosphatase activity ; GO:0004725 | inferred from sequence or structural similarity <newline> protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | inferred from sequence or structural similarity <newline> JUN kinase phosphatase activity ; GO:0008579 | non-traceable author statement <newline> JUN kinase phosphatase activity ; GO:0008579 | traceable author statement <newline> protein tyrosine/serine/threonine phosphatase activity ; GO:0008138 | non-traceable author statement <newline> MAP kinase tyrosine/serine/threonine phosphatase activity ; GO:0017017 | traceable author statement <newline> protein tyrosine phosphatase activity ; GO:0004725 | inferred from electronic annotation with InterPro:IPR016130"]
[null,"FBgn0259176","bunched","bun","The gene bunched is referred to in FlyBase by the symbol Dmel\\bun (CG42281, FBgn0259176). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12456577..12546630. It has the cytological map location 33E5-33E9. Based on sequence similarity, it is predicted to have molecular function</span>: protein homodimerization activity. There is experimental evidence for 13 unique biological process</span> terms, many of which group under: regulation of biological process; anatomical structure development; reproductive process in a multicellular organism; regulation of developmental process; programmed cell death; ovarian follicle cell development; positive regulation of biological process; positive regulation of cell proliferation; regionalization; regulation of anatomical structure size; gland morphogenesis; regulation of apoptosis; negative regulation of Notch signaling pathway. 140 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: external compound sense organ; peripheral nervous system; adult segment; organ system; nervous system; female germline cyst; egg; chorion; thoracic segment; adult mesothoracic segment. It has 8 annotated transcripts and 8 annotated polypeptides.","decapentaplegic receptor signaling pathway ; GO:0008101 | inferred from genetic interaction with dpp <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype <newline> negative regulation of cell fate specification ; GO:0009996 | inferred from mutant phenotype <newline> ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype <newline> negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype <newline> cell fate determination ; GO:0001709 | non-traceable author statement <newline> dorsal appendage formation ; GO:0046843 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> compound eye development ; GO:0048749 | non-traceable author statement <newline> oogenesis ; GO:0048477 | non-traceable author statement <newline> positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype <newline> positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000580","cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | non-traceable author statement","protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000580"]
[null,"FBgn0259750","abrupt","ab","The gene abrupt is referred to in FlyBase by the symbol Dmel\\ab (CG4807, FBgn0259750). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:11210681..11261080. It has the cytological map location 32E1-32E2. Based on sequence similarity, it is predicted to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: border follicle cell migration; lysosome organization; dendrite morphogenesis; neuron development; muscle organ development; negative regulation of autophagy. 44 alleles are reported. The phenotypes of these alleles are annotated with 53 unique terms, many of which group under: hypodermal muscle of larval abdomen; adult segment; abdominal oblique muscle; adult mesothoracic segment; peripheral nervous system; sensory cluster; organ system; multidendritic neuron; larval abdominal segment 5; multi-cell-component structure. It has 4 annotated transcripts and 4 annotated polypeptides.","axon choice point recognition ; GO:0016198 | traceable author statement <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype <newline> lysosome organization ; GO:0007040 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:AF032676","specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from sequence or structural similarity with EMBL:AF032676 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000210, InterPro:IPR011333, InterPro:IPR013069 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0260635","thread","th","The gene thread is referred to in FlyBase by the symbol Dmel\\th (CG12284, FBgn0260635). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:16031505..16043755. It has the cytological map location 72C1-72D1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: apoptosis; spermatid nucleus differentiation; anti-apoptosis; border follicle cell migration; sensory organ development; cellular process; negative regulation of apoptosis; antennal morphogenesis; positive regulation of protein ubiquitination. 167 alleles are reported. The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: organ system; anatomical structure; embryonic segment; embryonic nervous system; female germline cyst; antennal segment; embryonic head; nervous system; peripheral nervous system; adult segment. It has 3 annotated transcripts and 3 annotated polypeptides.","anti-apoptosis ; GO:0006916 | inferred from direct assay <newline> anti-apoptosis ; GO:0006916 | inferred from genetic interaction with W AND inferred from genetic interaction with rpr <newline> apoptosis ; GO:0006915 | inferred from physical interaction with W AND inferred from physical interaction with rpr <newline> negative regulation of caspase activity ; GO:0043154 | traceable author statement <newline> anti-apoptosis ; GO:0006916 | non-traceable author statement <newline> anti-apoptosis ; GO:0006916 | traceable author statement <newline> apoptosis ; GO:0006915 | traceable author statement <newline> negative regulation of apoptosis ; GO:0043066 | traceable author statement <newline> protein monoubiquitination ; GO:0006513 | traceable author statement <newline> multicellular organismal development ; GO:0007275 | traceable author statement <newline> protein ubiquitination during ubiquitin-dependent protein catabolic process ; GO:0042787 | traceable author statement <newline> apoptosis ; GO:0006915 | non-traceable author statement <newline> spermatid nucleus differentiation ; GO:0007289 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Rac1 AND inferred from mutant phenotype <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype AND inferred from sequence or structural similarity <newline> negative regulation of apoptosis ; GO:0043066 | inferred from sequence or structural similarity with UniProtKB:P98170 <newline> germ cell migration ; GO:0008354 | traceable author statement <newline> antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> positive regulation of protein ubiquitination ; GO:0031398 | inferred from direct assay","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001370","ubiquitin-protein ligase activity ; GO:0004842 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with ik2 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841"]
[null,"FBgn0029857","wuho","wuho","The gene wuho is referred to in FlyBase by the symbol Dmel\\wuho (CG15897, FBgn0029857). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: oogenesis; spermatogenesis. 8 alleles are reported. The phenotypes of these alleles are annotated with: ovariole; egg chamber; spermatid cyst; spermatozoon. It has one annotated transcript and one annotated polypeptide. Protein features are: WD40 repeat; WD40 repeat 2; WD40 repeat, subgroup; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Gene sequence location is X:6182156..6183595.","spermatogenesis ; GO:0007283 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay","-"]
[null,"FBgn0011725","twin","twin","The gene twin is referred to in FlyBase by the symbol Dmel\\twin (CG31137, FBgn0011725). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: transcription regulator activity. There is experimental evidence that it is involved in the biological process</span>: oogenesis; nuclear-transcribed mRNA poly(A) tail shortening. 25 alleles are reported. The phenotypes of these alleles are annotated with: nurse cell ring canal; oocyte; egg chamber; nurse cell. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Endonuclease/exonuclease/phosphatase; Leucine-rich repeat; Leucine-rich repeat, typical subtype. Gene sequence location is 3R:20023310..20047687.","nuclear-transcribed mRNA poly(A) tail shortening ; GO:0000289 | inferred from mutant phenotype <newline> nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ; GO:0000288 | inferred from sequence or structural similarity with SGD_LOCUS:CCR4; SGD:S0000019 <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with SGD_LOCUS:CCR4; SGD:S0000019 <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay <newline> CCR4-NOT complex ; GO:0030014 | inferred from sequence or structural similarity with SGD_LOCUS:CCR4; SGD:S0000019 <newline> cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with SGD_LOCUS:CCR4; SGD:S0000019","transcription regulator activity ; GO:0030528 | inferred from sequence or structural similarity with SGD_LOCUS:CCR4; SGD:S0000019"]
[null,"FBgn0028468","tetracycline resistance","rtet","The gene tetracycline resistance is referred to in FlyBase by the symbol Dmel\\rtet (CG5760, FBgn0028468). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: sugar transmembrane transporter activity. There is experimental evidence that it is involved in the biological process</span>: oogenesis. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Major facilitator superfamily; Major facilitator superfamily MFS-1; Major facilitator superfamily, general substrate transporter; Sugar transporter, conserved site. Gene sequence location is 3R:16934170..16936554.","oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005829, InterPro:IPR011701","membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR005829","sugar transmembrane transporter activity ; GO:0051119 | inferred from sequence or structural similarity with EMBL:L11669"]
[null,"FBgn0024944","Octopamine receptor in mushroom bodies","Oamb","The gene Octopamine receptor in mushroom bodies is referred to in FlyBase by the symbol Dmel\\Oamb (CG3856, FBgn0024944). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: octopamine receptor activity. There is experimental evidence that it is involved in the biological process</span>: ovulation; elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger. 24 alleles are reported. The phenotype of these alleles is annotated with: ovariole. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: 7TM GPCR, rhodopsin-like; GPCR, rhodopsin-like superfamily. Gene sequence location is 3R:16514740..16540263.","ovulation ; GO:0030728 | inferred from mutant phenotype <newline> G-protein signaling, coupled to cAMP nucleotide second messenger ; GO:0007188 | NOT inferred from direct assay <newline> elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger ; GO:0051482 | inferred from direct assay <newline> octopamine or tyramine signaling pathway ; GO:0007211 | inferred from sequence or structural similarity","plasma membrane ; GO:0005886 | non-traceable author statement <newline> integral to plasma membrane ; GO:0005887 | inferred by curator from GO:0004989 <newline> integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276","octopamine receptor activity ; GO:0004989 | non-traceable author statement <newline> G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity <newline> octopamine receptor activity ; GO:0004989 | inferred from direct assay"]
[]
["Nervous system development/ behavior"]
[null,"FBgn0000448","Hormone receptor-like in 46","Hr46","The gene Hormone receptor-like in 46 is referred to in FlyBase by the symbol Dmel\\Hr46 (CG33183, FBgn0000448). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6092959..6124853. It has the cytological map location 46F5-46F7. There is experimental evidence that it has the molecular function</span>: protein binding; ligand-dependent nuclear receptor activity. There is experimental evidence that it is involved in the biological process</span>: mushroom body development. 56 alleles are reported. The phenotypes of these alleles are annotated with: taenidial fold; mushroom body; embryonic peripheral nervous system; adult head; puparium. It has 4 annotated transcripts and 4 annotated polypeptides.","regulation of development, heterochronic ; GO:0040034 | traceable author statement <newline> metamorphosis ; GO:0007552 | traceable author statement <newline> mushroom body development ; GO:0016319 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000324, InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR001723, InterPro:IPR008946, InterPro:IPR013088","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q8R1B8 <newline> nucleus ; GO:0005634 | non-traceable author statement","ligand-dependent nuclear receptor activity ; GO:0004879 | inferred from direct assay <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | inferred from sequence or structural similarity with UniProtKB:Q8R1B8 <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with MGD:Rora; MGI:MGI:104661 <newline> protein binding ; GO:0005515 | inferred from physical interaction with rig <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | non-traceable author statement <newline> steroid hormone receptor activity ; GO:0003707 | inferred from electronic annotation with InterPro:IPR000536, InterPro:IPR008946 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628"]
[null,"FBgn0000472","diminutive","dm","The gene diminutive is referred to in FlyBase by the symbol Dmel\\dm (CG10798, FBgn0000472). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3267216..3280049. It has the cytological map location 3D2. There is experimental evidence that it has the molecular function</span>: transcription factor activity; protein binding; DNA binding. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: regulation of biological process; regulation of metabolic process; multicellular organismal development; regulation of growth; embryonic development; cell proliferation; embryonic development ending in birth or egg hatching; cell cycle; regulation of apoptosis; positive regulation of cellular biosynthetic process; anatomical structure development; cellular process; embryonic pattern specification; negative regulation of Notch signaling pathway. 55 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; peripheral nervous system; nervous system; external compound sense organ; female germline cyst; cell cycle; nucleus; thoracic segment; imaginal precursor; intracellular membrane-bounded organelle. It has one annotated transcript and one annotated polypeptide.","regulation of transcription, DNA-dependent ; GO:0006355 | inferred from direct assay <newline> cell proliferation ; GO:0008283 | inferred from expression pattern <newline> embryonic development ending in birth or egg hatching ; GO:0009792 | inferred from expression pattern <newline> positive regulation of cell growth ; GO:0030307 | traceable author statement <newline> positive regulation of growth ; GO:0045927 | traceable author statement <newline> regulation of cell size ; GO:0008361 | traceable author statement <newline> positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement <newline> DNA endoreduplication ; GO:0042023 | inferred from mutant phenotype <newline> cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype <newline> regulation of organ growth ; GO:0046620 | inferred from mutant phenotype <newline> regulation of cell growth ; GO:0001558 | inferred from mutant phenotype <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | traceable author statement <newline> regulation of cell cycle ; GO:0051726 | traceable author statement <newline> positive regulation of transcription ; GO:0045941 | inferred from mutant phenotype <newline> neurogenesis ; GO:0022008 | inferred from genetic interaction with Egfr <newline> embryonic pattern specification ; GO:0009880 | inferred from genetic interaction with Egfr <newline> negative regulation of Notch signaling pathway ; GO:0045746 | inferred from genetic interaction with N <newline> regulation of apoptosis ; GO:0042981 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:L00039 <newline> protein complex ; GO:0043234 | inferred from physical interaction with gro","DNA binding ; GO:0003677 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:L00039 <newline> protein binding ; GO:0005515 | inferred from physical interaction with lid <newline> protein binding ; GO:0005515 | inferred from physical interaction with gro"]
[null,"FBgn0000504","doublesex","dsx","The gene doublesex is referred to in FlyBase by the symbol Dmel\\dsx (CG11094, FBgn0000504). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3750045..3793130. It has the cytological map location 84E5-84E6. There is experimental evidence that it has the molecular function</span>: protein binding; protein homodimerization activity. There is experimental evidence that it is involved in the biological process</span>: imaginal disc-derived female genitalia development; imaginal disc-derived male genitalia development; genital disc development. 116 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; adult segment; region of integument; adult; peripheral nervous system; imaginal precursor; nervous system; hub cell; larval abdominal segment 8; male accessory gland; female genitalia; external compound sense organ; female germline cyst. It has 3 annotated transcripts and 3 annotated polypeptides.","imaginal disc-derived female genitalia development ; GO:0007486 | inferred from genetic interaction with tra2 <newline> genital disc development ; GO:0035215 | inferred from mutant phenotype <newline> imaginal disc-derived male genitalia development ; GO:0007485 | inferred from genetic interaction with tra2 <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | non-traceable author statement <newline> positive regulation of transcription, DNA-dependent ; GO:0045893 | non-traceable author statement <newline> female somatic sex determination ; GO:0019101 | traceable author statement <newline> spermatogenesis ; GO:0007283 | non-traceable author statement <newline> sex determination ; GO:0007530 | non-traceable author statement <newline> somatic sex determination ; GO:0018993 | non-traceable author statement <newline> transcription from RNA polymerase II promoter ; GO:0006366 | non-traceable author statement <newline> sex differentiation ; GO:0007548 | non-traceable author statement <newline> courtship behavior ; GO:0007619 | non-traceable author statement <newline> male courtship behavior, veined wing generated song production ; GO:0045433 | non-traceable author statement <newline> female somatic sex determination ; GO:0019101 | non-traceable author statement <newline> male courtship behavior, veined wing generated song production ; GO:0045433 | traceable author statement <newline> male somatic sex determination ; GO:0019102 | non-traceable author statement <newline> female analia development ; GO:0045497 | non-traceable author statement <newline> imaginal disc-derived female genitalia development ; GO:0007486 | non-traceable author statement <newline> genital disc development ; GO:0035215 | traceable author statement <newline> genital disc sexually dimorphic development ; GO:0035263 | traceable author statement <newline> male analia development ; GO:0045496 | non-traceable author statement <newline> imaginal disc-derived male genitalia development ; GO:0007485 | non-traceable author statement <newline> sex comb development ; GO:0045498 | traceable author statement <newline> female sex differentiation ; GO:0046660 | traceable author statement <newline> sex-specific pigmentation ; GO:0048071 | traceable author statement <newline> central nervous system development ; GO:0007417 | traceable author statement <newline> sex differentiation ; GO:0007548 | traceable author statement <newline> sex-specific pigmentation ; GO:0048071 | non-traceable author statement <newline> genital disc morphogenesis ; GO:0007483 | traceable author statement <newline> negative regulation of developmental pigmentation ; GO:0048086 | traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | traceable author statement <newline> regulation of imaginal disc growth ; GO:0045570 | traceable author statement <newline> somatic sex determination ; GO:0018993 | traceable author statement <newline> behavior ; GO:0007610 | traceable author statement <newline> sex determination ; GO:0007530 | traceable author statement <newline> male sex differentiation ; GO:0046661 | traceable author statement <newline> nuclear mRNA splicing, via spliceosome ; GO:0000398 | traceable author statement <newline> regulation of transcription ; GO:0045449 | traceable author statement <newline> male courtship behavior ; GO:0008049 | traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001275","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:AF130728; protein_id:AAD40474.1","specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from sequence or structural similarity with EMBL:AF130728; protein_id:AAD40474.1 <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | non-traceable author statement <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | traceable author statement <newline> DNA binding ; GO:0003677 | traceable author statement <newline> mRNA binding ; GO:0003729 | non-traceable author statement <newline> transcription regulator activity ; GO:0030528 | traceable author statement <newline> protein homodimerization activity ; GO:0042803 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with ix <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001275"]
[null,"FBgn0000536","easily shocked","eas","The gene easily shocked is referred to in FlyBase by the symbol Dmel\\eas (CG3525, FBgn0000536). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16172360..16179654. It has the cytological map location 14B7. There is experimental evidence that it has the molecular function</span>: ethanolamine kinase activity. There is experimental evidence that it is involved in the biological process</span>: response to mechanical stimulus; asymmetric neuroblast division; brain development; mushroom body development; mechanosensory behavior. 26 alleles are reported. The phenotypes of these alleles are annotated with: mushroom body beta'-lobe; calyx of mushroom body; mushroom body beta-lobe; mushroom body alpha-lobe; mushroom body alpha'-lobe. It has 5 annotated transcripts and 5 annotated polypeptides.","brain development ; GO:0007420 | inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | traceable author statement <newline> mushroom body development ; GO:0016319 | traceable author statement <newline> associative learning ; GO:0008306 | traceable author statement <newline> habituation ; GO:0046959 | traceable author statement <newline> mushroom body development ; GO:0016319 | inferred from mutant phenotype <newline> phosphorylation ; GO:0016310 | non-traceable author statement <newline> mechanosensory behavior ; GO:0007638 | inferred from mutant phenotype <newline> response to mechanical stimulus ; GO:0009612 | inferred from mutant phenotype <newline> phosphatidylethanolamine biosynthetic process ; GO:0006646 | non-traceable author statement <newline> asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype <newline> response to mechanical stimulus ; GO:0009612 | inferred from genetic interaction with kcc","-","ethanolamine kinase activity ; GO:0004305 | inferred from direct assay <newline> ethanolamine kinase activity ; GO:0004305 | non-traceable author statement <newline> choline kinase activity ; GO:0004103 | non-traceable author statement <newline> choline kinase activity ; GO:0004103 | traceable author statement"]
[null,"FBgn0000547","echinoid","ed","The gene echinoid is referred to in FlyBase by the symbol Dmel\\ed (CG12676, FBgn0000547). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:4031379..4115059. It has the cytological map location 24D4-24D6. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; organ development; cell adhesion; regulation of developmental process; regulation of biological process; cell-cell adhesion; homophilic cell adhesion; regulation of neurogenesis; actin filament-based process; behavioral interaction between organisms; regulation of epidermal growth factor receptor signaling pathway. 60 alleles are reported. The phenotypes of these alleles are annotated with 29 unique terms, many of which group under: peripheral nervous system; external compound sense organ; nervous system; adult segment; adult mesothoracic segment; embryonic nervous system; organ system; histaminergic neuron; embryonic segment; primordium. It has one annotated transcript and one annotated polypeptide.","epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype <newline> cell adhesion ; GO:0007155 | inferred from sequence or structural similarity <newline> negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with Egfr AND inferred from genetic interaction with Gap1 AND inferred from genetic interaction with Ras85D AND inferred from genetic interaction with argos AND inferred from genetic interaction with rho AND inferred from genetic interaction with rl AND inferred from genetic interaction with sty AND inferred from mutant phenotype <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | inferred from mutant phenotype AND inferred from physical interaction with Nrg <newline> negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> homophilic cell adhesion ; GO:0007156 | inferred from direct assay AND inferred from mutant phenotype <newline> negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype <newline> contractile actin filament bundle assembly ; GO:0030038 | inferred from mutant phenotype <newline> muscle organ morphogenesis ; GO:0048644 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> cell-cell adhesion ; GO:0016337 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype <newline> mushroom body development ; GO:0016319 | inferred from mutant phenotype","integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> cell-cell adherens junction ; GO:0005913 | inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with Grip"]
[null,"FBgn0000575","extra macrochaetae","emc","The gene extra macrochaetae is referred to in FlyBase by the symbol Dmel\\emc (CG1007, FBgn0000575). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:749406..753505. It has the cytological map location 61C9. There is experimental evidence that it has the molecular function</span>: transcription repressor activity; protein heterodimerization activity. There is experimental evidence for 19 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; sensory organ development; organ development; behavior; reproductive process in a multicellular organism; cell proliferation; negative regulation of molecular function; compound eye cone cell differentiation; embryonic development via the syncytial blastoderm; locomotory behavior; negative regulation of cellular biosynthetic process; reproductive developmental process; neuromuscular process; behavioral interaction between organisms. 94 alleles are reported. The phenotypes of these alleles are annotated with 42 unique terms, many of which group under: peripheral nervous system; organ system; nervous system; adult segment; external compound sense organ; adult mesothoracic segment; primordium; female germline cyst; midgut constriction; germ layer; Malpighian tubule. It has one annotated transcript and one annotated polypeptide.","negative regulation of transcription ; GO:0016481 | traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> sensory organ development ; GO:0007423 | traceable author statement <newline> sex determination ; GO:0007530 | inferred from genetic interaction with dpn, Sxl <newline> spermatid development ; GO:0007286 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from genetic interaction with Egfr AND inferred from genetic interaction with vn AND inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from genetic interaction with Egfr AND inferred from genetic interaction with vn AND inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from genetic interaction with bs AND inferred from genetic interaction with net AND inferred from genetic interaction with px AND inferred from mutant phenotype <newline> negative regulation of transcription ; GO:0016481 | non-traceable author statement <newline> sensory organ development ; GO:0007423 | non-traceable author statement <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | non-traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> sex determination, primary response to X:A ratio ; GO:0007541 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype <newline> bristle morphogenesis ; GO:0008407 | traceable author statement <newline> R8 cell fate commitment ; GO:0007460 | non-traceable author statement <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> midgut development ; GO:0007494 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> brain morphogenesis ; GO:0048854 | inferred from mutant phenotype <newline> startle response ; GO:0001964 | inferred from mutant phenotype <newline> locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype <newline> R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype <newline> compound eye cone cell differentiation ; GO:0042675 | inferred from mutant phenotype <newline> progression of morphogenetic furrow during compound eye morphogenesis ; GO:0007458 | inferred from mutant phenotype <newline> R3/R4 cell differentiation ; GO:0048056 | inferred from mutant phenotype <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype <newline> negative regulation of DNA binding ; GO:0043392 | inferred from direct assay <newline> negative regulation of transcription ; GO:0016481 | inferred from direct assay","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P41137 <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from direct assay","transcription corepressor activity ; GO:0003714 | inferred from sequence or structural similarity with UniProtKB:P41137 <newline> protein binding ; GO:0005515 | non-traceable author statement <newline> transcription corepressor activity ; GO:0003714 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | inferred from direct assay <newline> protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da inferred from physical interaction with ac inferred from physical interaction with sc inferred from physical interaction with l(1)sc <newline> protein heterodimerization activity ; GO:0046982 | inferred from physical interaction with da"]
[null,"FBgn0000658","four-jointed","fj","The gene four-jointed is referred to in FlyBase by the symbol Dmel\\fj (CG10917, FBgn0000658). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14120268..14123816. It has the cytological map location 55C1. There is experimental evidence that it has the molecular function</span>: protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: cell-cell signaling; imaginal disc-derived wing vein specification; establishment of epithelial cell apical/basal polarity; imaginal disc growth; imaginal disc-derived leg joint morphogenesis. 46 alleles are reported. The phenotypes of these alleles are annotated with 27 unique terms, many of which group under: adult segment; adult mesothoracic segment; appendage segment; organ system; thoracic segment; external compound sense organ; peripheral nervous system; metatarsus; antennal segment; nervous system. It has one annotated transcript and one annotated polypeptide.","cell-cell signaling ; GO:0007267 | inferred from direct assay AND inferred from sequence or structural similarity <newline> imaginal disc growth ; GO:0007446 | inferred from mutant phenotype <newline> cell-cell signaling ; GO:0007267 | inferred from expression pattern AND inferred from mutant phenotype <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype <newline> imaginal disc-derived leg joint morphogenesis ; GO:0016348 | inferred from mutant phenotype <newline> establishment of epithelial cell apical/basal polarity ; GO:0045198 | inferred from mutant phenotype <newline> establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement <newline> establishment of planar polarity ; GO:0001736 | traceable author statement <newline> cell-cell signaling ; GO:0007267 | non-traceable author statement <newline> imaginal disc development ; GO:0007444 | non-traceable author statement <newline> proximal/distal pattern formation, imaginal disc ; GO:0007449 | non-traceable author statement","plasma membrane ; GO:0005886 | inferred from direct assay AND inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | non-traceable author statement","protein kinase activity ; GO:0004672 | inferred from direct assay"]
[null,"FBgn0000721","foraging","for","The gene foraging is referred to in FlyBase by the symbol Dmel\\for (CG10033, FBgn0000721). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:3622071..3656951. It has the cytological map location 24A2-24A4. There is experimental evidence that it has the molecular function</span>: cGMP-dependent protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: larval feeding behavior; habituation; regulation of heart contraction; protein amino acid phosphorylation; short-term memory; long-term memory; larval locomotory behavior. 73 alleles are reported. The phenotypes of these alleles are annotated with: adult Malpighian tubule; embryonic/larval tracheal system; crystal cell. It has 11 annotated transcripts and 11 annotated polypeptides.","larval feeding behavior ; GO:0030536 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay <newline> larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> larval feeding behavior ; GO:0030536 | traceable author statement <newline> feeding behavior ; GO:0007631 | traceable author statement <newline> regulation of heart contraction ; GO:0008016 | inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from mutant phenotype <newline> short-term memory ; GO:0007614 | inferred from mutant phenotype <newline> habituation ; GO:0046959 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from direct assay","cyclic nucleotide-dependent protein kinase activity ; GO:0004690 | inferred from sequence or structural similarity <newline> cGMP-dependent protein kinase activity ; GO:0004692 | inferred from direct assay <newline> protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement <newline> cGMP-dependent protein kinase activity ; GO:0004692 | non-traceable author statement <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR002374, InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0000723","Fps oncogene analog","Fps85D","The gene Fps oncogene analog is referred to in FlyBase by the symbol Dmel\\Fps85D (CG8874, FBgn0000723). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5193321..5220265. It has the cytological map location 85D13-85D15. Based on sequence similarity, it is predicted to have molecular function</span>: protein tyrosine kinase activity. There is experimental evidence that it is involved in the biological process</span>: dorsal closure, elongation of leading edge cells; dorsal closure; actin filament bundle formation; axon guidance; photoreceptor cell morphogenesis; dorsal closure, amnioserosa morphology change. 18 alleles are reported. The phenotypes of these alleles are annotated with: dorsal closure embryo; amnioserosa; ventral midline. It has 4 annotated transcripts and 4 annotated polypeptides.","protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> photoreceptor cell morphogenesis ; GO:0008594 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from genetic interaction with Src42A <newline> dorsal closure, elongation of leading edge cells ; GO:0007394 | inferred from mutant phenotype <newline> dorsal closure, amnioserosa morphology change ; GO:0046664 | inferred from mutant phenotype <newline> actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR017441","plasma membrane ; GO:0005886 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | non-traceable author statement <newline> membrane ; GO:0016020 | non-traceable author statement <newline> adherens junction ; GO:0005912 | inferred from direct assay","protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity <newline> protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement <newline> protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity with UniProtKB:P00541 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR017441 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000980, InterPro:IPR020685"]
[null,"FBgn0001104","G protein alphai subunit 65A","G-ialpha65A","The gene G protein ?i subunit 65A is referred to in FlyBase by the symbol Dmel\\G-i?65A (CG10060, FBgn0001104). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:6965844..6973153. It has the cytological map location 65D5. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: asymmetric protein localization involved in cell fate determination; asymmetric neuroblast division; establishment of spindle orientation; establishment of glial blood-brain barrier; cortical actin cytoskeleton organization; septate junction assembly; regulation of protein localization; asymmetric cell division; ventral cord development. 28 alleles are reported. The phenotypes of these alleles are annotated with: RP2 neuron; neuroblast; embryonic neuroblast; chaeta; medial triple row; RP2sib neuron; EL neuron. It has one annotated transcript and one annotated polypeptide.","G-protein coupled receptor protein signaling pathway ; GO:0007186 | inferred from sequence or structural similarity with UniProtKB:P41776 <newline> establishment of mitotic spindle localization ; GO:0040001 | traceable author statement <newline> asymmetric protein localization involved in cell fate determination ; GO:0045167 | inferred from mutant phenotype <newline> asymmetric cell division ; GO:0008356 | inferred from mutant phenotype <newline> G-protein coupled receptor protein signaling pathway ; GO:0007186 | non-traceable author statement <newline> establishment of spindle orientation ; GO:0051294 | inferred from mutant phenotype <newline> asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype <newline> regulation of protein localization ; GO:0032880 | inferred from mutant phenotype <newline> septate junction assembly ; GO:0019991 | inferred from mutant phenotype <newline> establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype <newline> ventral cord development ; GO:0007419 | inferred from mutant phenotype <newline> cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR011025","heterotrimeric G-protein complex ; GO:0005834 | inferred from sequence or structural similarity with UniProtKB:P41776 <newline> cell cortex ; GO:0005938 | traceable author statement <newline> heterotrimeric G-protein complex ; GO:0005834 | non-traceable author statement <newline> apical cortex ; GO:0045179 | inferred from direct assay","GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with UniProtKB:P41776 <newline> protein binding ; GO:0005515 | non-traceable author statement <newline> GTPase activity ; GO:0003924 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with raps <newline> protein binding ; GO:0005515 | inferred from physical interaction with loco <newline> GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001408 <newline> signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR001019, InterPro:IPR001408, InterPro:IPR011025"]
[null,"FBgn0001138","grain","grn","The gene grain is referred to in FlyBase by the symbol Dmel\\grn (CG9656, FBgn0001138). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3973072..4007164. It has the cytological map location 84F1. Based on sequence similarity, it is predicted to have molecular function</span>: general RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: tissue development; organ morphogenesis. 13 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; embryonic abdomen; cephalopharyngeal skeleton; embryonic segment; cuticle; embryonic neuron; spiracle; pharyngeal sclerite; embryonic nervous system; integumentary specialisation. It has 2 annotated transcripts and 2 annotated polypeptides.","organ morphogenesis ; GO:0009887 | inferred from mutant phenotype <newline> tissue development ; GO:0009888 | inferred from mutant phenotype <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with UniProtKB:P23770 <newline> organ morphogenesis ; GO:0009887 | non-traceable author statement <newline> tissue development ; GO:0009888 | non-traceable author statement","nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGD:Gata3; MGI:MGI:95663","general RNA polymerase II transcription factor activity ; GO:0016251 | non-traceable author statement <newline> general RNA polymerase II transcription factor activity ; GO:0016251 | inferred from sequence or structural similarity with UniProtKB:P23770 <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR000679 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000679, InterPro:IPR013088 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000679, InterPro:IPR013088"]
[null,"FBgn0001235","homothorax","hth","The gene homothorax is referred to in FlyBase by the symbol Dmel\\hth (CG17117, FBgn0001235). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:6335569..6464386. It has the cytological map location 86C1-86C3. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of gene-specific transcription from RNA polymerase II promoter; compound eye development; specification of segmental identity, antennal segment; specification of segmental identity, head; segmentation; compound eye photoreceptor fate commitment; brain development; imaginal disc-derived wing morphogenesis; haltere morphogenesis; imaginal disc-derived leg morphogenesis. 64 alleles are reported. The phenotypes of these alleles are annotated with 63 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; thoracic segment; external compound sense organ; appendage segment; adult mesothoracic segment; embryonic segment; embryonic nervous system; organ system; antennal segment. It has 8 annotated transcripts and 8 annotated polypeptides.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> brain development ; GO:0007420 | inferred from mutant phenotype <newline> proximal/distal pattern formation ; GO:0009954 | traceable author statement <newline> specification of organ identity ; GO:0010092 | traceable author statement <newline> compound eye photoreceptor fate commitment ; GO:0001752 | inferred from mutant phenotype <newline> leg disc proximal/distal pattern formation ; GO:0007479 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> specification of segmental identity, head ; GO:0007380 | inferred from mutant phenotype <newline> specification of segmental identity, antennal segment ; GO:0007383 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> imaginal disc-derived leg morphogenesis ; GO:0007480 | inferred from mutant phenotype <newline> haltere morphogenesis ; GO:0048735 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with MGD:Meis1; MGI:MGI:104717 <newline> transcription factor activity ; GO:0003700 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356"]
[null,"FBgn0001269","invected","inv","The gene invected is referred to in FlyBase by the symbol Dmel\\inv (CG17835, FBgn0001269). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7361970..7394688. It has the cytological map location 47F15-47F17. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: neuroblast fate determination; compartment specification. 37 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; thoracic segment; adult; cuticle; multi-cell-component structure; embryonic hindgut; embryonic nervous system; nervous system; region of integument; developing anatomical structure. It has 4 annotated transcripts and 4 annotated polypeptides.","compartment pattern formation ; GO:0007386 | inferred from mutant phenotype AND inferred from sequence or structural similarity with en <newline> neuroblast fate determination ; GO:0007400 | inferred from genetic interaction with en, gsb AND inferred from genetic interaction with en, gsb, ptc <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with EMBL:AF213356 <newline> compartment pattern formation ; GO:0007386 | traceable author statement <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | traceable author statement","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q05925 <newline> nucleus ; GO:0005634 | non-traceable author statement","RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity with EMBL:AF213356 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000047, InterPro:IPR001356"]
[null,"FBgn0001297","kayak","kay","The gene kayak is referred to in FlyBase by the symbol Dmel\\kay (CG33956, FBgn0001297). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25592497..25619838. It has the cytological map location 99B10-99C1. There is experimental evidence that it has the molecular function</span>: protein binding; sequence-specific DNA binding; RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; sensory organ development; response to stress; organ development; organ morphogenesis; cell cycle; cellular component movement; response to external stimulus; regulation of cyclin-dependent protein kinase activity; ovarian follicle cell development; immune response; embryonic development via the syncytial blastoderm; wound healing. 47 alleles are reported. The phenotypes of these alleles are annotated with 44 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; nervous system; embryonic nervous system; external compound sense organ; peripheral nervous system; multi-cell-component structure; imaginal precursor; thoracic segment. It has 4 annotated transcripts and 4 annotated polypeptides.","regulation of cyclin-dependent protein kinase activity during G2/M ; GO:0031660 | inferred from mutant phenotype <newline> second mitotic wave during compound eye morphogenesis ; GO:0016330 | inferred from mutant phenotype <newline> wing disc development ; GO:0035220 | inferred from mutant phenotype <newline> central nervous system development ; GO:0007417 | inferred from mutant phenotype <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> midgut development ; GO:0007494 | inferred from mutant phenotype <newline> JNK cascade ; GO:0007254 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> imaginal disc fusion, thorax closure ; GO:0046529 | traceable author statement <newline> ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype <newline> response to wounding ; GO:0009611 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | non-traceable author statement <newline> R3/R4 cell fate commitment ; GO:0007464 | traceable author statement <newline> establishment of planar polarity ; GO:0001736 | non-traceable author statement <newline> wound healing ; GO:0042060 | inferred from mutant phenotype <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Pvr <newline> R3/R4 cell fate commitment ; GO:0007464 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR004827, InterPro:IPR011616","nucleus ; GO:0005634 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","sequence-specific DNA binding ; GO:0043565 | inferred from direct assay <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from direct assay <newline> transcription factor activity ; GO:0003700 | traceable author statement <newline> transcription factor binding ; GO:0008134 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with Cka <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> transcription factor binding ; GO:0008134 | non-traceable author statement <newline> protein heterodimerization activity ; GO:0046982 | inferred from sequence or structural similarity <newline> protein dimerization activity ; GO:0046983 | inferred from electronic annotation with InterPro:IPR011616 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR004827, InterPro:IPR011616"]
[null,"FBgn0001404","egghead","egh","The gene egghead is referred to in FlyBase by the symbol Dmel\\egh (CG9659, FBgn0001404). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2482534..2492638. It has the cytological map location 3A6. There is experimental evidence that it has the molecular function</span>: beta-1,4-mannosyltransferase activity. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: reproductive process in a multicellular organism; anatomical structure development; multicellular organism reproduction; ovarian follicle cell development; cellular component movement; organ morphogenesis; gamete generation; transport; regulation of response to stimulus; cell fate commitment; establishment or maintenance of polarity of follicular epithelium. 60 alleles are reported. The phenotypes of these alleles are annotated with 28 unique terms, many of which group under: organ system; adult segment; nervous system; multi-cell-component structure; female germline cyst; adult; peripheral nervous system; larval head segment; adult brain; egg; lamina plexus; embryonic nervous system; external compound sense organ. It has 2 annotated transcripts and 2 annotated polypeptides.","border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype <newline> ovarian follicle cell-cell adhesion ; GO:0007299 | inferred from mutant phenotype <newline> maintenance of polarity of follicular epithelium ; GO:0042248 | inferred from mutant phenotype <newline> morphogenesis of follicular epithelium ; GO:0016333 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> cell fate commitment ; GO:0045165 | inferred from mutant phenotype <newline> germ cell development ; GO:0007281 | inferred from mutant phenotype <newline> oocyte localization during germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype <newline> oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype <newline> optic lobe placode formation ; GO:0001744 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> negative regulation of female receptivity, post-mating ; GO:0045434 | inferred from mutant phenotype <newline> regulation of oviposition ; GO:0046662 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | traceable author statement <newline> dsRNA transport ; GO:0033227 | inferred from mutant phenotype","integral to plasma membrane ; GO:0005887 | non-traceable author statement","beta-1,4-mannosyltransferase activity ; GO:0019187 | inferred from direct assay"]
[null,"FBgn0002543","leak","lea","The gene leak is referred to in FlyBase by the symbol Dmel\\lea (CG5481, FBgn0002543). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:1380086..1420449. It has the cytological map location 22A1. It is reported to have molecular function</span>: axon guidance receptor activity; receptor activity. There is experimental evidence that it is involved in the biological process</span>: salivary gland boundary specification; axon guidance; cardioblast cell fate specification; positive regulation of cell-cell adhesion; mushroom body development; embryonic heart tube development; neuron migration; ventral cord development; central complex development. 35 alleles are reported. The phenotypes of these alleles are annotated with 41 unique terms, many of which group under: organ system; nervous system; multi-cell-component structure; embryonic nervous system; adult segment; peripheral nervous system; embryonic neuron; abdominal transverse muscle; cephalopharyngeal skeleton; commissure. It has one annotated transcript and one annotated polypeptide.","axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> ventral cord development ; GO:0007419 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | traceable author statement <newline> tracheal outgrowth, open tracheal system ; GO:0007426 | traceable author statement <newline> neuron migration ; GO:0001764 | inferred from mutant phenotype <newline> salivary gland boundary specification ; GO:0007432 | inferred from mutant phenotype <newline> embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from genetic interaction with robo AND inferred from mutant phenotype <newline> positive regulation of cell-cell adhesion ; GO:0022409 | inferred from mutant phenotype <newline> cardioblast cell fate specification ; GO:0042685 | inferred from mutant phenotype <newline> mushroom body development ; GO:0016319 | inferred from mutant phenotype <newline> central complex development ; GO:0048036 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | non-traceable author statement","axon guidance receptor activity ; GO:0008046 | non-traceable author statement <newline> receptor activity ; GO:0004872 | traceable author statement"]
[null,"FBgn0002643","mastermind","mam","The gene mastermind is referred to in FlyBase by the symbol Dmel\\mam (CG8118, FBgn0002643). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9878686..9947861. It has the cytological map location 50C23-50D3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: transcription coactivator activity. There is experimental evidence that it is involved in the biological process</span>: germ-line stem cell maintenance; heart morphogenesis; apposition of dorsal and ventral imaginal disc-derived wing surfaces; mesodermal cell fate determination; imaginal disc-derived wing margin morphogenesis; somatic stem cell maintenance; bristle morphogenesis; imaginal disc-derived wing morphogenesis; asymmetric cell division. 194 alleles are reported. The phenotypes of these alleles are annotated with 73 unique terms, many of which group under: synaptic neuropil subdomain; adult segment; antennal segment; embryonic nervous system; adult mesothoracic segment; embryonic neuron; peripheral nervous system; embryonic glial cell; germarium; external compound sense organ. It has 3 annotated transcripts and 3 annotated polypeptides.","ectoderm development ; GO:0007398 | traceable author statement <newline> mesodermal cell fate determination ; GO:0007500 | inferred from mutant phenotype <newline> apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> asymmetric cell division ; GO:0008356 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | traceable author statement <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> heart morphogenesis ; GO:0003007 | inferred from mutant phenotype <newline> somatic stem cell maintenance ; GO:0035019 | inferred from mutant phenotype <newline> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from electronic annotation with InterPro:IPR019082 <newline> Notch signaling pathway ; GO:0007219 | inferred from electronic annotation with InterPro:IPR019082","nucleus ; GO:0005634 | inferred from direct assay AND inferred from sequence or structural similarity <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nuclear speck ; GO:0016607 | inferred from electronic annotation with InterPro:IPR019082","transcription coactivator activity ; GO:0003713 | inferred from electronic annotation with InterPro:IPR019082"]
[null,"FBgn0002732","E(spl) region transcript malpha","malpha","The gene E(spl) region transcript m? is referred to in FlyBase by the symbol Dmel\\m? (CG8337, FBgn0002732). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21836615..21837290. It has the cytological map location 96F10. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: sensory organ development; Notch signaling pathway; cell fate specification. 12 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: peripheral nervous system; nervous system; organ system; adult segment; adult mesothoracic segment; eo support cell; sensillum; tormogen cell; integumentary plate; central nervous system; wing margin bristle. It has one annotated transcript and one annotated polypeptide.","Notch signaling pathway ; GO:0007219 | inferred from mutant phenotype <newline> cell fate specification ; GO:0001708 | inferred from mutant phenotype <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement","-","-"]
[null,"FBgn0002733","E(spl) region transcript mbeta","HLHmbeta","The gene E(spl) region transcript m? is referred to in FlyBase by the symbol Dmel\\HLHm? (CG14548, FBgn0002733). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21830648..21831745. It has the cytological map location 96F9. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: negative regulation of transcription from RNA polymerase II promoter. 7 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; wing margin bristle; macrochaeta; anterior crossvein; scutellar bristle; microchaeta; wing vein. It has one annotated transcript and one annotated polypeptide.","negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> negative regulation of transcription ; GO:0016481 | non-traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> compound eye development ; GO:0048749 | traceable author statement","nucleus ; GO:0005634 | inferred by curator from GO:0003677 <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR011598","transcription factor activity ; GO:0003700 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> transcription repressor activity ; GO:0016564 | inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853 <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from direct assay"]
[null,"FBgn0003028","ovo","ovo","The gene ovo is referred to in FlyBase by the symbol Dmel\\ovo (CG6824, FBgn0003028). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:4942330..4964962. It has the cytological map location 4E2. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding; transcription repressor activity; transcription activator activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: pheromone metabolic process; cuticle pigmentation; non-sensory hair organization; positive regulation of transcription from RNA polymerase II promoter; cuticle pattern formation; germ-line sex determination; negative regulation of transcription from RNA polymerase II promoter; adult feeding behavior; epidermal cell differentiation. 186 alleles are reported. The phenotypes of these alleles are annotated with 28 unique terms, many of which group under: organ system; female germline cyst; adult segment; cuticle; peripheral nervous system; external compound sense organ; egg; antennal segment; nervous system; cell part. It has 5 annotated transcripts and 5 annotated polypeptides.","cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype <newline> cuticle pigmentation ; GO:0048067 | inferred from mutant phenotype <newline> epidermal cell differentiation ; GO:0009913 | inferred from mutant phenotype <newline> non-sensory hair organization ; GO:0035316 | inferred from mutant phenotype <newline> non-sensory hair organization ; GO:0035316 | traceable author statement <newline> regulation of transcription ; GO:0045449 | traceable author statement <newline> pheromone metabolic process ; GO:0042810 | inferred from mutant phenotype <newline> female germ-line sex determination ; GO:0019099 | non-traceable author statement <newline> cuticle development ; GO:0042335 | traceable author statement <newline> oogenesis ; GO:0048477 | traceable author statement <newline> germ-line sex determination ; GO:0018992 | inferred from mutant phenotype inferred from genetic interaction with UniProtKB:P19339 <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype <newline> positive regulation of transcription from RNA polymerase II promoter ; GO:0045944 | inferred from mutant phenotype <newline> adult feeding behavior ; GO:0008343 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q60821 <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred by curator from GO:0003677","sequence-specific DNA binding ; GO:0043565 | inferred from direct assay <newline> DNA binding ; GO:0003677 | traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity with UniProtKB:Q60821 <newline> DNA binding ; GO:0003677 | inferred from direct assay <newline> transcription repressor activity ; GO:0016564 | inferred from mutant phenotype <newline> transcription activator activity ; GO:0016563 | inferred from mutant phenotype <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0003162","Punch","Pu","The gene Punch is referred to in FlyBase by the symbol Dmel\\Pu (CG9441, FBgn0003162). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:17062822..17070121. It has the cytological map location 57C7-57C8. There is experimental evidence that it has the molecular function</span>: GTP cyclohydrolase activity; GTP cyclohydrolase I activity. There is experimental evidence that it is involved in the biological process</span>: preblastoderm mitotic cell cycle; cuticle pigmentation; pteridine biosynthetic process; embryonic pattern specification; compound eye pigmentation; larval chitin-based cuticle development. 80 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; cuticle; adult segment; extended germ band embryo; peripheral nervous system; anatomical structure; adult mesothoracic segment; nervous system; integumentary system; blastoderm embryo; acellular anatomical structure; thoracic segment; cephalopharyngeal skeleton; external compound sense organ. It has 3 annotated transcripts and 3 annotated polypeptides.","tetrahydrobiopterin biosynthetic process ; GO:0006729 | non-traceable author statement <newline> compound eye pigmentation ; GO:0048072 | inferred from mutant phenotype <newline> pteridine biosynthetic process ; GO:0006728 | inferred from mutant phenotype <newline> preblastoderm mitotic cell cycle ; GO:0035185 | inferred from mutant phenotype <newline> larval chitin-based cuticle development ; GO:0008363 | inferred from mutant phenotype <newline> cuticle pigmentation ; GO:0048067 | inferred from mutant phenotype <newline> embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype <newline> tetrahydrofolate biosynthetic process ; GO:0046654 | inferred from electronic annotation with InterPro:IPR001474, InterPro:IPR018234","cytoplasm ; GO:0005737 | inferred from direct assay","GTP cyclohydrolase I activity ; GO:0003934 | inferred from sequence or structural similarity with UniProtKB:P22288 <newline> GTP cyclohydrolase I activity ; GO:0003934 | non-traceable author statement <newline> GTP cyclohydrolase activity ; GO:0003933 | inferred from direct assay <newline> GTP cyclohydrolase I activity ; GO:0003934 | inferred from direct assay"]
[null,"FBgn0003165","pumilio","pum","The gene pumilio is referred to in FlyBase by the symbol Dmel\\pum (CG9755, FBgn0003165). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4895479..5063417. It has the cytological map location 85C4-85D1. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: regulation of synaptic transmission; synaptic transmission; dendrite morphogenesis; pole cell migration; long-term memory; head involution; regulation of synaptic growth at neuromuscular junction. 130 alleles are reported. The phenotypes of these alleles are annotated with 41 unique terms, many of which group under: organ system; embryonic abdomen; embryonic segment; female germline cyst; anatomical structure; nervous system; peripheral nervous system; germarium; embryonic tagma; embryonic neuron; multi-cell-component structure; cephalopharyngeal skeleton. It has 5 annotated transcripts and 5 annotated polypeptides.","regulation of synaptic transmission ; GO:0050804 | inferred from mutant phenotype <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from mutant phenotype <newline> cell fate determination ; GO:0001709 | traceable author statement <newline> germ cell development ; GO:0007281 | traceable author statement <newline> germ-line stem cell division ; GO:0042078 | traceable author statement <newline> synaptic transmission ; GO:0007268 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> pole cell migration ; GO:0007280 | inferred from mutant phenotype <newline> germ-line stem cell division ; GO:0042078 | non-traceable author statement <newline> cell migration ; GO:0016477 | traceable author statement <newline> anterior/posterior axis specification, embryo ; GO:0008595 | traceable author statement <newline> nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay ; GO:0000288 | traceable author statement <newline> mitosis ; GO:0007067 | traceable author statement <newline> negative regulation of cell cycle ; GO:0045786 | traceable author statement <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | traceable author statement <newline> pole cell migration ; GO:0007280 | traceable author statement <newline> long-term memory ; GO:0007616 | traceable author statement <newline> negative regulation of translation ; GO:0017148 | traceable author statement <newline> positive regulation of translation ; GO:0045727 | traceable author statement <newline> oogenesis ; GO:0048477 | traceable author statement <newline> regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from direct assay","cytoplasm ; GO:0005737 | non-traceable author statement","mRNA 3'-UTR binding ; GO:0003730 | traceable author statement <newline> protein binding ; GO:0005515 | traceable author statement <newline> mRNA binding ; GO:0003729 | inferred from sequence or structural similarity with EMBL:AF315592; protein_id:AAG31807.1 AND inferred from sequence or structural similarity with MGD:Pum2; MGI:MGI:1931751 AND traceable author statement <newline> translation repressor activity, nucleic acid binding ; GO:0000900 | traceable author statement"]
[null,"FBgn0003310","Star","S","The gene Star is referred to in FlyBase by the symbol Dmel\\S (CG4385, FBgn0003310). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:1050877..1077811. It has the cytological map location 21E4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: epidermal growth factor ligand processing; stomatogastric nervous system development; determination of genital disc primordium; protein targeting to Golgi; compound eye retinal cell programmed cell death; regulation of epidermal growth factor receptor signaling pathway; ommatidial rotation; imaginal disc-derived wing morphogenesis; behavioral response to ethanol. 151 alleles are reported. The phenotypes of these alleles are annotated with 58 unique terms, many of which group under: organ system; embryonic nervous system; peripheral nervous system; nervous system; adult segment; external compound sense organ; adult mesothoracic segment; embryonic neuron; multi-cell-component structure; female germline cyst; commissure. It has 2 annotated transcripts and 2 annotated polypeptides.","epidermal growth factor ligand processing ; GO:0007174 | inferred from genetic interaction with spi <newline> protein targeting to Golgi ; GO:0000042 | inferred from genetic interaction with spi <newline> regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | inferred from genetic interaction with rho, spi <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | traceable author statement <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | non-traceable author statement <newline> compound eye photoreceptor development ; GO:0042051 | non-traceable author statement <newline> protein targeting to Golgi ; GO:0000042 | non-traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> embryonic development ; GO:0009790 | traceable author statement <newline> mesoderm development ; GO:0007498 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> photoreceptor cell development ; GO:0042461 | traceable author statement <newline> regulation of epidermal growth factor receptor signaling pathway ; GO:0042058 | traceable author statement <newline> protein targeting to Golgi ; GO:0000042 | traceable author statement <newline> determination of genital disc primordium ; GO:0035225 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | traceable author statement <newline> behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype <newline> stomatogastric nervous system development ; GO:0007421 | inferred from mutant phenotype <newline> compound eye retinal cell programmed cell death ; GO:0046667 | inferred from mutant phenotype <newline> ommatidial rotation ; GO:0016318 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> membrane ; GO:0016020 | non-traceable author statement <newline> Golgi apparatus ; GO:0005794 | non-traceable author statement <newline> endoplasmic reticulum ; GO:0005783 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | traceable author statement","-"]
[null,"FBgn0003326","scabrous","sca","The gene scabrous is referred to in FlyBase by the symbol Dmel\\sca (CG17579, FBgn0003326). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8668049..8689515. It has the cytological map location 49C3-49D3. It is reported to have molecular function</span>: signal transducer activity. There is experimental evidence that it is involved in the biological process</span>: female meiosis chromosome segregation; compound eye development; imaginal disc-derived wing margin morphogenesis; nervous system development; ommatidial rotation; bristle morphogenesis. 71 alleles are reported. The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: peripheral nervous system; nervous system; adult segment; external compound sense organ; organ system; adult mesothoracic segment; plasma membrane part; plasma membrane; eo support cell; acrostichal bristle; imaginal precursor; adult cuticle; antennal segment. It has 2 annotated transcripts and 2 annotated polypeptides.","bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | inferred from genetic interaction with N <newline> female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype <newline> ommatidial rotation ; GO:0016318 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> lateral inhibition ; GO:0046331 | non-traceable author statement <newline> regulation of R8 cell spacing in compound eye ; GO:0045468 | traceable author statement <newline> regulation of R8 cell spacing in compound eye ; GO:0045468 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from genetic interaction with hh AND inferred from mutant phenotype <newline> R8 cell fate commitment ; GO:0007460 | traceable author statement <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002181, InterPro:IPR014716","fibrinogen complex ; GO:0005577 | inferred from sequence or structural similarity with NCBI_gi:4758348 <newline> extracellular region ; GO:0005576 | non-traceable author statement","signal transducer activity ; GO:0004871 | traceable author statement <newline> receptor binding ; GO:0005102 | inferred from electronic annotation with InterPro:IPR002181, InterPro:IPR014716"]
[null,"FBgn0003371","shaggy","sgg","The gene shaggy is referred to in FlyBase by the symbol Dmel\\sgg (CG2621, FBgn0003371). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2527983..2571879. It has the cytological map location 3A8-3B1. There is experimental evidence that it has the molecular function</span>: protein kinase activity; kinase activity. There is experimental evidence for 16 unique biological process</span> terms, many of which group under: anatomical structure development; regulation of biological process; reproductive process in a multicellular organism; organ development; learning; regulation of circadian rhythm; multicellular organism reproduction; learning or memory; regionalization; biopolymer modification; circadian rhythm; regulation of developmental process; embryonic pattern specification; olfactory learning; entrainment of circadian clock; regulation of metabolic process. 149 alleles are reported. The phenotypes of these alleles are annotated with 44 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; abdominal ventral denticle belt; nervous system; external compound sense organ; cuticle; larval abdominal segment; embryonic/larval hemocoel. It has 15 annotated transcripts and 15 annotated polypeptides.","synaptic growth at neuromuscular junction ; GO:0051124 | inferred from mutant phenotype <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> circadian rhythm ; GO:0007623 | inferred from mutant phenotype <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype <newline> heart development ; GO:0007507 | non-traceable author statement <newline> protein localization ; GO:0008104 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> negative regulation of Wnt receptor signaling pathway ; GO:0030178 | traceable author statement <newline> blastoderm segmentation ; GO:0007350 | non-traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> bristle morphogenesis ; GO:0008407 | non-traceable author statement <newline> circadian rhythm ; GO:0007623 | non-traceable author statement <newline> locomotor rhythm ; GO:0045475 | non-traceable author statement <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from direct assay <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay <newline> regulation of proteolysis ; GO:0030162 | inferred from direct assay <newline> circadian rhythm ; GO:0007623 | traceable author statement <newline> Notch signaling pathway ; GO:0007219 | traceable author statement <newline> regulation of protein import into nucleus ; GO:0042306 | traceable author statement <newline> rhythmic behavior ; GO:0007622 | traceable author statement <newline> regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype <newline> entrainment of circadian clock ; GO:0009649 | inferred from mutant phenotype <newline> wing and notum subfield formation ; GO:0035309 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> olfactory learning ; GO:0008355 | inferred from mutant phenotype <newline> habituation ; GO:0046959 | inferred from mutant phenotype <newline> regulation of circadian rhythm ; GO:0042752 | inferred from mutant phenotype","-","protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity <newline> protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement <newline> kinase activity ; GO:0016301 | inferred from direct assay <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> glycogen synthase kinase 3 activity ; GO:0004696 | non-traceable author statement <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017442 <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR002290, InterPro:IPR008271"]
[null,"FBgn0003396","schnurri","shn","The gene schnurri is referred to in FlyBase by the symbol Dmel\\shn (CG7734, FBgn0003396). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7061325..7104918. It has the cytological map location 47D6-47D7. There is experimental evidence that it has the molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: olfactory learning; ectoderm development; learning or memory; cell proliferation; imaginal disc-derived wing vein morphogenesis; wing disc anterior/posterior pattern formation; wing disc dorsal/ventral pattern formation; imaginal disc-derived wing morphogenesis; midgut development. 108 alleles are reported. The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; peripheral nervous system; adult segment; embryonic nervous system; adult mesothoracic segment; nervous system; external compound sense organ; primordium; embryonic peripheral nervous system; embryonic head; midgut constriction; podocyte; organ system subdivision; multi-cell-component structure; spiracle. It has 4 annotated transcripts and 4 annotated polypeptides.","ectoderm development ; GO:0007398 | inferred from mutant phenotype <newline> midgut development ; GO:0007494 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from mutant phenotype <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from genetic interaction with dpp AND inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> learning or memory ; GO:0007611 | inferred from mutant phenotype <newline> olfactory learning ; GO:0008355 | inferred from mutant phenotype <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement <newline> negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement <newline> compound eye morphogenesis ; GO:0001745 | non-traceable author statement <newline> negative regulation of cell proliferation ; GO:0008285 | non-traceable author statement <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap","nucleus ; GO:0005634 | non-traceable author statement <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:X51435; protein_id:CAA35798.1 <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from mutant phenotype <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR003604, InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0003716","thickveins","tkv","The gene thickveins is referred to in FlyBase by the symbol Dmel\\tkv (CG14026, FBgn0003716). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:5218996..5271353. It has the cytological map location 25D1-25D2. There is experimental evidence that it has the molecular function</span>: transforming growth factor beta receptor activity, type I; specific transcriptional repressor activity; transforming growth factor beta binding. There is experimental evidence for 19 unique biological process</span> terms, many of which group under: anatomical structure development; regulation of biological process; regulation of developmental process; organ development; organ morphogenesis; reproductive process in a multicellular organism; synaptic transmission; regionalization; positive regulation of developmental process; enzyme linked receptor protein signaling pathway. 103 alleles are reported. The phenotypes of these alleles are annotated with 87 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; embryonic/larval tracheal system; primordium; peripheral nervous system; germarium; embryonic nervous system; egg; external compound sense organ; late extended germ band embryo. It has 4 annotated transcripts and 4 annotated polypeptides.","neuromuscular synaptic transmission ; GO:0007274 | inferred from mutant phenotype <newline> decapentaplegic receptor signaling pathway ; GO:0008101 | inferred from mutant phenotype inferred from genetic interaction with dpp <newline> dorsal/ventral pattern formation ; GO:0009953 | inferred from mutant phenotype inferred from genetic interaction with dpp <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | inferred from genetic interaction with dpp AND inferred from physical interaction with dpp <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from genetic interaction with dpp AND inferred from mutant phenotype <newline> anterior/posterior pattern formation, imaginal disc ; GO:0007448 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> positive regulation of synaptic growth at neuromuscular junction ; GO:0045887 | inferred from mutant phenotype <newline> wing disc anterior/posterior pattern formation ; GO:0048100 | inferred from mutant phenotype <newline> BMP signaling pathway ; GO:0030509 | traceable author statement <newline> germ-line stem cell division ; GO:0042078 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | non-traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> morphogenesis of a branching structure ; GO:0001763 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | non-traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> transforming growth factor beta receptor complex assembly ; GO:0007181 | non-traceable author statement <newline> negative regulation of salivary gland boundary specification ; GO:0045705 | traceable author statement <newline> compound eye morphogenesis ; GO:0001745 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> genital disc development ; GO:0035215 | inferred from mutant phenotype <newline> regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype <newline> chorion-containing eggshell formation ; GO:0007304 | inferred from genetic interaction with sax <newline> positive regulation of muscle organ development ; GO:0048636 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> regulation of cell-cell adhesion ; GO:0022407 | inferred from mutant phenotype <newline> regulation of cell differentiation ; GO:0045595 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR003605, InterPro:IPR008271, InterPro:IPR017441, InterPro:IPR017442","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with babo <newline> plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> multivesicular body ; GO:0005771 | inferred from direct assay","transforming growth factor beta binding ; GO:0050431 | inferred from physical interaction with dpp <newline> transforming growth factor beta receptor activity, type I ; GO:0005025 | inferred from physical interaction with dpp <newline> transforming growth factor beta receptor activity, type I ; GO:0005025 | inferred from sequence or structural similarity <newline> transforming growth factor beta receptor activity, type I ; GO:0005025 | non-traceable author statement <newline> protein kinase activity ; GO:0004672 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR003605, InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0003870","tramtrack","ttk","The gene tramtrack is referred to in FlyBase by the symbol Dmel\\ttk (CG1856, FBgn0003870). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27539591..27561114. It has the cytological map location 100D1. There is experimental evidence that it has the molecular function</span>: protein binding; specific transcriptional repressor activity; chromatin binding; protein homodimerization activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; inter-male aggressive behavior; startle response; brain morphogenesis; dendrite morphogenesis; neuron development; ovarian follicle cell development; negative regulation of transcription, DNA-dependent; dorsal appendage formation; locomotion involved in locomotory behavior. 153 alleles are reported. The phenotypes of these alleles are annotated with 70 unique terms, many of which group under: peripheral nervous system; nervous system; external compound sense organ; adult segment; embryonic nervous system; multi-cell-component structure; adult mesothoracic segment; embryonic glial cell; imaginal precursor; larval abdominal segment 5. It has 8 annotated transcripts and 8 annotated polypeptides.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> R7 cell development ; GO:0045467 | traceable author statement <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> cell fate determination ; GO:0001709 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> brain morphogenesis ; GO:0048854 | inferred from mutant phenotype <newline> startle response ; GO:0001964 | inferred from mutant phenotype <newline> locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | inferred from direct assay <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype","polytene chromosome ; GO:0005700 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | non-traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with CoRest <newline> chromatin binding ; GO:0003682 | inferred from direct assay <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> protein homodimerization activity ; GO:0042803 | inferred from physical interaction with UniProtKB:P17789 <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q08605 <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR017956 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0003964","ultraspiracle","usp","The gene ultraspiracle is referred to in FlyBase by the symbol Dmel\\usp (CG4380, FBgn0003964). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1932831..1935343. It has the cytological map location 2C7. There is experimental evidence that it has the molecular function</span>: ecdysteroid hormone receptor activity; protein binding; lipid binding; protein heterodimerization activity; protein homodimerization activity. There is experimental evidence that it is involved in the biological process</span>: border follicle cell migration; dendrite morphogenesis; neuron development; neuron remodeling; muscle organ development. 22 alleles are reported. The phenotypes of these alleles are annotated with: dendrite; terminal filament; embryonic/larval anterior spiracle; midgut imaginal island; dorsal multidendritic neuron ddaC; imaginal disc. It has one annotated transcript and one annotated polypeptide.","neuron remodeling ; GO:0016322 | inferred from mutant phenotype <newline> ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | non-traceable author statement <newline> metamorphosis ; GO:0007552 | non-traceable author statement <newline> negative regulation of cell differentiation ; GO:0045596 | traceable author statement <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | traceable author statement <newline> regulation of development, heterochronic ; GO:0040034 | traceable author statement <newline> positive regulation of transcription ; GO:0045941 | traceable author statement <newline> dendrite morphogenesis ; GO:0048813 | non-traceable author statement <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000324, InterPro:IPR000536, InterPro:IPR001628, InterPro:IPR001723, InterPro:IPR008946, InterPro:IPR013088","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P51128 <newline> ecdysone receptor holocomplex ; GO:0008230 | traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> polytene chromosome ; GO:0005700 | non-traceable author statement <newline> dendrite ; GO:0030425 | inferred from mutant phenotype","ecdysteroid hormone receptor activity ; GO:0004884 | inferred from direct assay <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | inferred from sequence or structural similarity with UniProtKB:P51128 <newline> transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with UniProtKB:P51128 <newline> protein binding ; GO:0005515 | inferred from physical interaction with rig <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> ecdysteroid hormone receptor activity ; GO:0004884 | non-traceable author statement <newline> ligand-dependent nuclear receptor activity ; GO:0004879 | non-traceable author statement <newline> juvenile hormone binding ; GO:0005500 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with egg <newline> lipid binding ; GO:0008289 | inferred from direct assay <newline> protein homodimerization activity ; GO:0042803 | inferred from direct assay <newline> protein heterodimerization activity ; GO:0046982 | inferred from direct assay <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001628, InterPro:IPR013088 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001628"]
[null,"FBgn0003997","Wrinkled","W","The gene Wrinkled is referred to in FlyBase by the symbol Dmel\\W (CG5123, FBgn0003997). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:18160842..18178737. It has the cytological map location 75C1. Its molecular function is unknown. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: anatomical structure development; positive regulation of programmed cell death; programmed cell death; regulation of biological process; gland morphogenesis; cell death; regulation of apoptosis; response to light stimulus; response to radiation; entrainment of circadian clock. 63 alleles are reported. The phenotypes of these alleles are annotated with 35 unique terms, many of which group under: nervous system; peripheral nervous system; organ system; external compound sense organ; adult segment; embryonic nervous system; cephalopharyngeal skeleton; antennal segment; multi-cell-component structure; larval head segment; imaginal precursor. It has one annotated transcript and one annotated polypeptide.","response to red light ; GO:0010114 | inferred from mutant phenotype <newline> entrainment of circadian clock by photoperiod ; GO:0043153 | inferred from mutant phenotype <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> instar larval or pupal development ; GO:0002165 | inferred from mutant phenotype <newline> programmed cell death ; GO:0012501 | inferred from mutant phenotype <newline> programmed cell death ; GO:0012501 | inferred from genetic interaction with rpr AND inferred from mutant phenotype <newline> induction of apoptosis ; GO:0006917 | traceable author statement <newline> induction of apoptosis ; GO:0006917 | inferred from genetic interaction with Dcp-1 AND inferred from genetic interaction with th <newline> salivary gland cell autophagic cell death ; GO:0035071 | non-traceable author statement <newline> ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | inferred from expression pattern <newline> nurse cell apoptosis ; GO:0045476 | NOT traceable author statement <newline> ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | non-traceable author statement <newline> embryonic development via the syncytial blastoderm ; GO:0001700 | traceable author statement <newline> compound eye retinal cell programmed cell death ; GO:0046667 | traceable author statement <newline> programmed cell death ; GO:0012501 | traceable author statement <newline> regulation of retinal cell programmed cell death ; GO:0046668 | non-traceable author statement <newline> larval midgut cell programmed cell death ; GO:0035096 | non-traceable author statement <newline> apoptosis ; GO:0006915 | non-traceable author statement <newline> protein ubiquitination ; GO:0016567 | traceable author statement <newline> regulation of proteolysis ; GO:0030162 | traceable author statement <newline> regulation of organ growth ; GO:0046620 | inferred from mutant phenotype <newline> apoptosis ; GO:0006915 | traceable author statement <newline> induction of apoptosis ; GO:0006917 | inferred from mutant phenotype <newline> larval midgut cell programmed cell death ; GO:0035096 | inferred from genetic interaction with rpr <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from genetic interaction with rpr AND inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> cell death ; GO:0008219 | inferred from mutant phenotype <newline> head involution ; GO:0008258 | non-traceable author statement <newline> induction of apoptosis ; GO:0006917 | non-traceable author statement <newline> antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype <newline> positive regulation of apoptosis ; GO:0043065 | inferred from mutant phenotype","-","-"]
[null,"FBgn0004399","pipsqueak","psq","The gene pipsqueak is referred to in FlyBase by the symbol Dmel\\psq (CG2368, FBgn0004399). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6445409..6503753. It has the cytological map location 47A13-47B1. It is reported to have molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: olfactory behavior; imaginal disc-derived wing morphogenesis. 79 alleles are reported. The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: embryonic abdomen; embryonic segment; organ system; embryonic tagma; peripheral nervous system; female germline cyst; external compound sense organ; adult segment; nervous system; adult mesothoracic segment. It has 12 annotated transcripts and 12 annotated polypeptides.","pole plasm assembly ; GO:0007315 | non-traceable author statement <newline> gene silencing ; GO:0016458 | traceable author statement <newline> olfactory behavior ; GO:0042048 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype","nucleus ; GO:0005634 | traceable author statement","DNA binding ; GO:0003677 | non-traceable author statement <newline> DNA binding ; GO:0003677 | traceable author statement <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR011526 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000210, InterPro:IPR011333, InterPro:IPR013069"]
[null,"FBgn0004449","Tenascin major","Ten-m","The gene Tenascin major is referred to in FlyBase by the symbol Dmel\\Ten-m (CG5723, FBgn0004449). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:22286132..22400987. It has the cytological map location 79D4-79E3. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; R7 cell development; bristle development; compound eye photoreceptor development; periodic partitioning by pair rule gene; compound eye corneal lens development; cell adhesion; compound eye morphogenesis. 47 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; abdominal ventral denticle belt; cuticle; larval abdominal segment; external compound sense organ; nervous system; peripheral nervous system; thoracic segment; metathoracic ventral denticle belt; embryonic head; embryonic nervous system; abdominal 5 ventral denticle belt. It has 2 annotated transcripts and 2 annotated polypeptides.","cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> cell adhesion ; GO:0007155 | inferred from sequence or structural similarity with EMBL:AB025410 <newline> periodic partitioning by pair rule gene ; GO:0007366 | inferred from mutant phenotype <newline> compound eye photoreceptor development ; GO:0042051 | inferred from mutant phenotype <newline> R7 cell development ; GO:0045467 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> bristle development ; GO:0022416 | inferred from mutant phenotype <newline> compound eye corneal lens development ; GO:0048058 | inferred from mutant phenotype","proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity <newline> integral to plasma membrane ; GO:0005887 | inferred from direct assay <newline> proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity with EMBL:AB025410","-"]
[null,"FBgn0004647","Notch","N","The gene Notch is referred to in FlyBase by the symbol Dmel\\N (CG3936, FBgn0004647). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3028905..3066295. It has the cytological map location 3C7-3C9. There is experimental evidence that it has the molecular function</span>: protein binding; specific transcriptional repressor activity; transcription activator activity. There is experimental evidence for 54 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; organ development; regulation of developmental process; sensory organ development; organ morphogenesis; regulation of neurogenesis; cellular component movement; ovarian follicle cell development; regulation of biological process. 653 alleles are reported. The phenotypes of these alleles are annotated with 219 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; adult mesothoracic segment; organ system; external compound sense organ; embryonic nervous system; multi-cell-component structure; primordium; embryonic neuron. It has one annotated transcript and one annotated polypeptide.","stem cell differentiation ; GO:0048863 | inferred from mutant phenotype <newline> regulation of neurogenesis ; GO:0050767 | inferred from mutant phenotype <newline> ectoderm development ; GO:0007398 | traceable author statement <newline> mesoderm development ; GO:0007498 | inferred from mutant phenotype <newline> ovarian follicle cell stalk formation ; GO:0030713 | inferred from mutant phenotype <newline> Notch signaling pathway ; GO:0007219 | non-traceable author statement <newline> leg joint morphogenesis ; GO:0035111 | inferred from mutant phenotype <newline> leg segmentation ; GO:0035286 | inferred from mutant phenotype <newline> R8 cell development ; GO:0045463 | traceable author statement <newline> cell adhesion ; GO:0007155 | traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> glial cell fate determination ; GO:0007403 | inferred from mutant phenotype <newline> peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype <newline> germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> muscle cell fate determination ; GO:0007521 | inferred from mutant phenotype <newline> regulation of cardioblast cell fate specification ; GO:0042686 | inferred from mutant phenotype <newline> regulation of growth ; GO:0040008 | inferred from genetic interaction with scrib AND inferred from mutant phenotype <newline> foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype <newline> oocyte localization during germarium-derived egg chamber formation ; GO:0030720 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> anesthesia-resistant memory ; GO:0007615 | NOT inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from mutant phenotype <newline> lateral inhibition ; GO:0046331 | traceable author statement <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype <newline> ovarian follicle cell development ; GO:0030707 | inferred from mutant phenotype <newline> sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype <newline> cell fate specification ; GO:0001708 | traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> anterior/posterior pattern formation ; GO:0009952 | traceable author statement <newline> leg disc morphogenesis ; GO:0007478 | traceable author statement <newline> cell fate commitment ; GO:0045165 | non-traceable author statement <newline> negative regulation of fusion cell fate specification ; GO:0035157 | traceable author statement <newline> negative regulation of terminal cell fate specification, open tracheal system ; GO:0035155 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> imaginal disc growth ; GO:0007446 | traceable author statement <newline> imaginal disc pattern formation ; GO:0007447 | traceable author statement <newline> skeletal muscle tissue development ; GO:0007519 | inferred from mutant phenotype <newline> ovarian follicle cell stalk formation ; GO:0030713 | traceable author statement <newline> peripheral nervous system development ; GO:0007422 | traceable author statement <newline> germarium-derived egg chamber formation ; GO:0007293 | traceable author statement <newline> germarium-derived female germ-line cyst encapsulation ; GO:0030708 | traceable author statement <newline> morphogenesis of follicular epithelium ; GO:0016333 | non-traceable author statement <newline> oocyte anterior/posterior axis specification ; GO:0007314 | traceable author statement <newline> dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | traceable author statement <newline> establishment of ommatidial planar polarity ; GO:0042067 | non-traceable author statement <newline> cell fate specification ; GO:0001708 | non-traceable author statement <newline> compound eye retinal cell programmed cell death ; GO:0046667 | traceable author statement <newline> second mitotic wave during compound eye morphogenesis ; GO:0016330 | non-traceable author statement <newline> R8 cell differentiation ; GO:0045465 | non-traceable author statement <newline> regulation of R8 cell spacing in compound eye ; GO:0045468 | non-traceable author statement <newline> dorsal/ventral pattern formation, imaginal disc ; GO:0007450 | traceable author statement <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | non-traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> lateral inhibition ; GO:0046331 | non-traceable author statement <newline> negative regulation of JNK cascade ; GO:0046329 | non-traceable author statement <newline> establishment of imaginal disc-derived wing hair orientation ; GO:0001737 | NOT non-traceable author statement <newline> establishment of ommatidial planar polarity ; GO:0042067 | traceable author statement <newline> crystal cell differentiation ; GO:0042688 | inferred from mutant phenotype <newline> embryonic hemopoiesis ; GO:0035162 | inferred from mutant phenotype <newline> hemocyte proliferation ; GO:0035172 | inferred from mutant phenotype <newline> larval lymph gland hemopoiesis ; GO:0035167 | inferred from mutant phenotype <newline> R3/R4 cell fate commitment ; GO:0007464 | non-traceable author statement <newline> retinal cell programmed cell death ; GO:0046666 | traceable author statement <newline> wing disc proximal/distal pattern formation ; GO:0007473 | traceable author statement <newline> regulation of crystal cell differentiation ; GO:0042689 | traceable author statement <newline> asymmetric cell division ; GO:0008356 | traceable author statement <newline> ventral cord development ; GO:0007419 | non-traceable author statement <newline> R7 cell differentiation ; GO:0045466 | traceable author statement <newline> regulation of mitotic cell cycle ; GO:0007346 | traceable author statement <newline> lymph gland crystal cell differentiation ; GO:0035170 | traceable author statement <newline> embryonic crystal cell differentiation ; GO:0035165 | traceable author statement <newline> long-term memory ; GO:0007616 | traceable author statement <newline> lymph gland development ; GO:0048542 | inferred from mutant phenotype <newline> negative regulation of compound eye photoreceptor development ; GO:0045316 | inferred from mutant phenotype <newline> positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype <newline> actin filament organization ; GO:0007015 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> compound eye cone cell fate commitment ; GO:0042676 | traceable author statement <newline> compound eye development ; GO:0048749 | non-traceable author statement <newline> compound eye development ; GO:0048749 | traceable author statement <newline> R8 cell fate commitment ; GO:0007460 | traceable author statement <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> heterophilic cell-cell adhesion ; GO:0007157 | inferred from mutant phenotype inferred from direct assay <newline> positive regulation of Notch signaling pathway ; GO:0045747 | inferred from mutant phenotype <newline> lamellocyte differentiation ; GO:0035171 | inferred from mutant phenotype <newline> response to symbiont ; GO:0009608 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype <newline> negative regulation of neurogenesis ; GO:0050768 | inferred from mutant phenotype <newline> epithelial cell type specification, open tracheal system ; GO:0035153 | inferred from mutant phenotype <newline> glial cell migration ; GO:0008347 | inferred from mutant phenotype <newline> glial cell differentiation ; GO:0010001 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> positive regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010552 | inferred from direct assay <newline> positive regulation of S phase of mitotic cell cycle ; GO:0045750 | inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from genetic interaction with klg <newline> R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype <newline> R1/R6 cell differentiation ; GO:0048052 | inferred from mutant phenotype <newline> eye-antennal disc development ; GO:0035214 | inferred from mutant phenotype <newline> regulation of cell differentiation ; GO:0045595 | inferred from mutant phenotype","intracellular ; GO:0005622 | inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> integral to membrane ; GO:0016021 | traceable author statement <newline> integral to plasma membrane ; GO:0005887 | non-traceable author statement <newline> intracellular ; GO:0005622 | non-traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | traceable author statement <newline> subapical complex ; GO:0035003 | inferred from direct assay <newline> adherens junction ; GO:0005912 | inferred from direct assay <newline> cytoplasmic vesicle ; GO:0031410 | colocalizes_with inferred from direct assay <newline> protein complex ; GO:0043234 | inferred from physical interaction with Su(H) <newline> integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR010660, InterPro:IPR011656","transmembrane receptor activity ; GO:0004888 | traceable author statement <newline> receptor activity ; GO:0004872 | non-traceable author statement <newline> transcription activator activity ; GO:0016563 | non-traceable author statement <newline> receptor activity ; GO:0004872 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with dx <newline> transmembrane receptor activity ; GO:0004888 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> protein binding ; GO:0005515 | inferred from physical interaction with shg <newline> transcription activator activity ; GO:0016563 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9VVI3 <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:Q9Y0H4 <newline> protein binding ; GO:0005515 | inferred from physical interaction with Su(H) <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097"]
[null,"FBgn0004657","myospheroid","mys","The gene myospheroid is referred to in FlyBase by the symbol Dmel\\mys (CG1560, FBgn0004657). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7955680..7964270. It has the cytological map location 7D5. It is reported to have molecular function</span>: cell adhesion molecule binding; receptor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; central nervous system development; germ-line stem cell maintenance; determination of adult lifespan; axon guidance; hemocyte migration; cell adhesion; muscle organ development; maintenance of epithelial integrity, open tracheal system; substrate-bound cell migration, cell extension. 141 alleles are reported. The phenotypes of these alleles are annotated with 55 unique terms, many of which group under: organ system; hypodermal muscle of larval abdomen; adult segment; primordium; nervous system; larval abdominal segment 5; adult mesothoracic segment; larval abdominal segment; extended germ band embryo; abdominal 7 longitudinal muscle; external compound sense organ. It has one annotated transcript and one annotated polypeptide.","central nervous system development ; GO:0007417 | inferred from mutant phenotype <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> cell migration ; GO:0016477 | traceable author statement <newline> midgut development ; GO:0007494 | traceable author statement <newline> muscle attachment ; GO:0016203 | traceable author statement <newline> calcium-dependent cell-cell adhesion ; GO:0016339 | traceable author statement <newline> calcium-dependent cell-matrix adhesion ; GO:0016340 | inferred from sequence or structural similarity <newline> cell-matrix adhesion ; GO:0007160 | traceable author statement <newline> heterophilic cell-cell adhesion ; GO:0007157 | traceable author statement <newline> apposition of dorsal and ventral imaginal disc-derived wing surfaces ; GO:0007475 | non-traceable author statement <newline> cell adhesion ; GO:0007155 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement <newline> tracheal outgrowth, open tracheal system ; GO:0007426 | traceable author statement <newline> maintenance of epithelial integrity, open tracheal system ; GO:0035160 | inferred from mutant phenotype <newline> hemocyte migration ; GO:0035099 | inferred from genetic interaction with Gef26 inferred from genetic interaction with R <newline> substrate-bound cell migration, cell extension ; GO:0006930 | inferred from genetic interaction with Gef26 <newline> determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> integrin-mediated signaling pathway ; GO:0007229 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812 <newline> cell-matrix adhesion ; GO:0007160 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812","focal adhesion ; GO:0005925 | inferred from sequence or structural similarity <newline> integrin complex ; GO:0008305 | inferred from sequence or structural similarity <newline> integrin complex ; GO:0008305 | non-traceable author statement <newline> cell leading edge ; GO:0031252 | inferred from direct assay <newline> integrin complex ; GO:0008305 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812","cell adhesion molecule binding ; GO:0050839 | traceable author statement <newline> receptor activity ; GO:0004872 | traceable author statement <newline> receptor activity ; GO:0004872 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812 <newline> binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR001169, InterPro:IPR002369, InterPro:IPR012012, InterPro:IPR012896, InterPro:IPR014836, InterPro:IPR015812"]
[null,"FBgn0004854","BarH2","B-H2","The gene BarH2 is referred to in FlyBase by the symbol Dmel\\B-H2 (CG5488, FBgn0004854). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:17208614..17218195. It has the cytological map location 16A1. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity; DNA binding; transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: sensory organ boundary specification; compound eye photoreceptor cell differentiation; leg disc proximal/distal pattern formation; eye-antennal disc morphogenesis; eye pigment granule organization; bristle morphogenesis. 8 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; thoracic segment; metatarsus; organ system; peripheral nervous system; appendage segment; adult mesothoracic segment; nervous system; eipithelial furrow; external compound sense organ. It has one annotated transcript and one annotated polypeptide.","sensory organ boundary specification ; GO:0008052 | inferred from mutant phenotype <newline> eye pigment granule organization ; GO:0008057 | inferred from mutant phenotype <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> eye-antennal disc morphogenesis ; GO:0007455 | inferred from mutant phenotype <newline> leg disc proximal/distal pattern formation ; GO:0007479 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970","nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR017970","specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> DNA binding ; GO:0003677 | non-traceable author statement <newline> transcription factor activity ; GO:0003700 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR001356"]
[null,"FBgn0004885","tolkin","tok","The gene tolkin is referred to in FlyBase by the symbol Dmel\\tok (CG6863, FBgn0004885). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:20545419..20574855. It has the cytological map location 96A18-96A19. Based on sequence similarity, it is predicted to have molecular function</span>: metalloendopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: motor axon guidance; axon guidance; defasciculation of motor neuron axon; imaginal disc-derived wing vein morphogenesis; protein maturation by peptide bond cleavage. 35 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; nervous system; adult segment; multi-cell-component structure; adult mesothoracic segment; peripheral nervous system; embryonic nervous system; thoracic segment; abdominal segmental nerve; abdominal longitudinal muscle. It has 2 annotated transcripts and 2 annotated polypeptides.","imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> protein maturation by peptide bond cleavage ; GO:0051605 | inferred from direct assay <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> motor axon guidance ; GO:0008045 | inferred from mutant phenotype <newline> defasciculation of motor neuron axon ; GO:0007415 | inferred from mutant phenotype <newline> proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001506, InterPro:IPR006026","-","metalloendopeptidase activity ; GO:0004222 | inferred from sequence or structural similarity with UniProtKB:P13497 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006026 <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR001881, InterPro:IPR018097"]
[null,"FBgn0005511","midline","mid","The gene midline is referred to in FlyBase by the symbol Dmel\\mid (CG6634, FBgn0005511). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:5461641..5467609. It has the cytological map location 25E2. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence for 12 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; regulation of biological process; regulation of developmental process; stem cell differentiation; neuroblast fate commitment; embryonic pattern specification; regulation of metabolic process; regionalization; neuroblast development; regulation of cell fate specification; cellular component movement; embryonic heart tube development; leg disc development; central nervous system development. 15 alleles are reported. The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: organ system; embryonic nervous system; primordium; adult segment; nervous system; cuticle; organ system subdivision; embryonic/larval dorsal vessel; peripheral nervous system; embryonic neuron. It has one annotated transcript and one annotated polypeptide.","segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> heart development ; GO:0007507 | inferred from mutant phenotype <newline> cardioblast cell fate commitment ; GO:0042684 | inferred from mutant phenotype <newline> embryonic heart tube development ; GO:0035050 | inferred from mutant phenotype <newline> regulation of cardioblast differentiation ; GO:0051890 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with EMBL:AC006379; protein_id:AAD21787.1 <newline> neuroblast fate specification ; GO:0014018 | inferred from mutant phenotype <newline> neuroblast development ; GO:0014019 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> central nervous system development ; GO:0007417 | inferred from mutant phenotype inferred from genetic interaction with HGTX <newline> negative regulation of gene expression ; GO:0010629 | inferred from mutant phenotype inferred from genetic interaction with HGTX <newline> leg disc pattern formation ; GO:0035223 | inferred from genetic interaction with H15 <newline> regulation of cell fate specification ; GO:0042659 | inferred from genetic interaction with H15 <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001699, InterPro:IPR018186","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:AC006379; protein_id:AAD21787.1","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:AC006379; protein_id:AAD21787.1"]
[null,"FBgn0005612","Sox box protein 14","Sox14","The gene Sox box protein 14 is referred to in FlyBase by the symbol Dmel\\Sox14 (CG3090, FBgn0005612). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19866744..19872700. It has the cytological map location 60A16. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis; neuron remodeling. 7 alleles are reported. The phenotypes of these alleles are annotated with: dendrite; dorsal multidendritic neuron ddaC. It has 2 annotated transcripts and 2 annotated polypeptides.","regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with UniProtKB:Q06945 <newline> dendrite morphogenesis ; GO:0048813 | inferred from genetic interaction with Mical <newline> neuron remodeling ; GO:0016322 | inferred from genetic interaction with Mical","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q06945 <newline> nucleus ; GO:0005634 | non-traceable author statement","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with UniProtKB:Q06945"]
[null,"FBgn0005630","longitudinals lacking","lola","The gene longitudinals lacking is referred to in FlyBase by the symbol Dmel\\lola (CG12052, FBgn0005630). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6369712..6430767. It has the cytological map location 47A11-47A13. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence for 12 unique biological process</span> terms, many of which group under: anatomical structure development; cell projection organization; cellular component movement; behavior; sensory organ development; organ morphogenesis; immune response; programmed cell death; neuromuscular process; behavioral interaction between organisms; locomotory behavior; regulation of metabolic process. 163 alleles are reported. The phenotypes of these alleles are annotated with 40 unique terms, many of which group under: peripheral nervous system; nervous system; abdominal lateral monoscolopidial chordotonal organ lch1; embryonic neuron; embryonic nervous system; organ system; multi-cell-component structure; adult segment; abdominal longitudinal muscle; ventral longitudinal muscle. It has 26 annotated transcripts and 26 annotated polypeptides.","axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> axonogenesis ; GO:0007409 | inferred from mutant phenotype <newline> positive regulation of transcription, DNA-dependent ; GO:0045893 | inferred from sequence or structural similarity with UniProtKB:Q08605 <newline> axon midline choice point recognition ; GO:0016199 | inferred from genetic interaction with robo AND inferred from genetic interaction with sli AND inferred from mutant phenotype <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> axon guidance ; GO:0007411 | non-traceable author statement <newline> axon guidance ; GO:0007411 | inferred from genetic interaction with SoxN <newline> brain morphogenesis ; GO:0048854 | inferred from mutant phenotype <newline> startle response ; GO:0001964 | inferred from mutant phenotype <newline> locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype <newline> nurse cell apoptosis ; GO:0045476 | inferred from mutant phenotype <newline> R7 cell development ; GO:0045467 | inferred from mutant phenotype <newline> R3/R4 cell fate commitment ; GO:0007464 | inferred from mutant phenotype <newline> regulation of gene-specific transcription ; GO:0032583 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from sequence or structural similarity with ttk AND inferred from sequence or structural similarity with HGNC_gene:ZBTB25; HGNC:13112; OMIM:194541 <newline> transcription activator activity ; GO:0016563 | inferred from sequence or structural similarity with UniProtKB:Q08605 <newline> protein binding ; GO:0005515 | inferred from physical interaction with JIL-1 <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0005634","zipper","zip","The gene zipper is referred to in FlyBase by the symbol Dmel\\zip (CG15792, FBgn0005634). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20878471..20899488. It has the cytological map location 60E12. There is experimental evidence that it has the molecular function</span>: myosin light chain binding. There is experimental evidence for 16 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; protein complex biogenesis; actin filament-based process; muscle cell differentiation; organ development; cell division; gland morphogenesis; epithelial cell differentiation; embryonic development via the syncytial blastoderm; establishment of protein localization; system process. 34 alleles are reported. The phenotypes of these alleles are annotated with 36 unique terms, many of which group under: organ system; cuticle; nervous system; peripheral nervous system; cytoplasmic part; external compound sense organ; adult segment; extended germ band embryo; acute muscle; cell projection; primordium. It has 8 annotated transcripts and 8 annotated polypeptides.","dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> muscle attachment ; GO:0016203 | NOT inferred from genetic interaction with l(2)gl <newline> muscle contraction ; GO:0006936 | inferred from mutant phenotype <newline> myofibril assembly ; GO:0030239 | inferred from mutant phenotype <newline> sarcomere organization ; GO:0045214 | inferred from mutant phenotype <newline> dorsal closure, leading edge cell differentiation ; GO:0046663 | inferred from mutant phenotype <newline> dorsal closure, spreading of leading edge cells ; GO:0007395 | inferred from mutant phenotype <newline> establishment of planar polarity ; GO:0001736 | non-traceable author statement <newline> cytokinesis ; GO:0000910 | inferred from mutant phenotype <newline> dorsal closure, amnioserosa morphology change ; GO:0046664 | inferred from mutant phenotype <newline> Malpighian tubule morphogenesis ; GO:0007443 | inferred from mutant phenotype <newline> head involution ; GO:0008258 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> ovarian follicle cell migration ; GO:0007297 | traceable author statement <newline> ecdysone-mediated induction of salivary gland cell autophagic cell death ; GO:0035072 | non-traceable author statement <newline> establishment of neuroblast polarity ; GO:0045200 | traceable author statement <newline> cytokinesis ; GO:0000910 | non-traceable author statement <newline> anatomical structure morphogenesis ; GO:0009653 | non-traceable author statement <newline> imaginal disc-derived wing hair organization ; GO:0035317 | inferred from genetic interaction with fz inferred from genetic interaction with dsh <newline> cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype <newline> myosin II filament assembly ; GO:0031036 | inferred from direct assay <newline> protein oligomerization ; GO:0051259 | inferred from direct assay <newline> establishment of protein localization ; GO:0045184 | inferred from mutant phenotype","unconventional myosin complex ; GO:0016461 | inferred from sequence or structural similarity <newline> myosin complex ; GO:0016459 | inferred from sequence or structural similarity <newline> Z disc ; GO:0030018 | inferred from direct assay <newline> apical cortex ; GO:0045179 | traceable author statement <newline> cell cortex ; GO:0005938 | inferred from mutant phenotype <newline> cytoskeleton ; GO:0005856 | non-traceable author statement <newline> unconventional myosin complex ; GO:0016461 | non-traceable author statement <newline> myosin II complex ; GO:0016460 | inferred from direct assay <newline> cleavage furrow ; GO:0032154 | inferred from direct assay <newline> cell cortex ; GO:0005938 | inferred from direct assay","ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity <newline> motor activity ; GO:0003774 | inferred from sequence or structural similarity with SGD_LOCUS:MYO1; SGD:S0001065 <newline> myosin light chain binding ; GO:0032027 | inferred from physical interaction with sqh inferred from physical interaction with Mlc-c <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001609, InterPro:IPR004009"]
[null,"FBgn0005672","spitz","spi","The gene spitz is referred to in FlyBase by the symbol Dmel\\spi (CG10334, FBgn0005672). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:19567899..19577324. It has the cytological map location 37F2. It is reported to have molecular function</span>: gurken receptor binding; epidermal growth factor receptor binding. There is experimental evidence that it is involved in the biological process</span>: oenocyte development; border follicle cell migration; stomatogastric nervous system development; spiracle morphogenesis, open tracheal system; negative regulation of apoptosis; determination of genital disc primordium; imaginal disc-derived wing morphogenesis; behavioral response to ethanol; peripheral nervous system development. 80 alleles are reported. The phenotypes of these alleles are annotated with 110 unique terms, many of which group under: peripheral nervous system; nervous system; organ system; external compound sense organ; embryonic nervous system; multi-cell-component structure; hypodermal muscle of larval abdomen; adult segment; cuticle; commissure. It has 7 annotated transcripts and 7 annotated polypeptides.","oenocyte development ; GO:0007438 | inferred from genetic interaction with abd-A AND inferred from mutant phenotype <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | traceable author statement <newline> positive regulation of epidermal growth factor receptor signaling pathway ; GO:0045742 | non-traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> epidermal growth factor receptor signaling pathway ; GO:0007173 | non-traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | non-traceable author statement <newline> G2/M transition of mitotic cell cycle ; GO:0000086 | non-traceable author statement <newline> second mitotic wave during compound eye morphogenesis ; GO:0016330 | non-traceable author statement <newline> R8 cell-mediated photoreceptor organization ; GO:0045470 | non-traceable author statement <newline> anti-apoptosis ; GO:0006916 | non-traceable author statement <newline> negative regulation of compound eye retinal cell programmed cell death ; GO:0046673 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> determination of genital disc primordium ; GO:0035225 | inferred from mutant phenotype <newline> spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype <newline> stomatogastric nervous system development ; GO:0007421 | inferred from mutant phenotype","extracellular region ; GO:0005576 | traceable author statement <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> Golgi apparatus ; GO:0005794 | inferred from genetic interaction with S <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> integral to membrane ; GO:0016021 | non-traceable author statement <newline> endoplasmic reticulum ; GO:0005783 | non-traceable author statement <newline> extracellular region ; GO:0005576 | non-traceable author statement","epidermal growth factor receptor binding ; GO:0005154 | traceable author statement <newline> epidermal growth factor receptor binding ; GO:0005154 | non-traceable author statement <newline> gurken receptor binding ; GO:0008317 | non-traceable author statement"]
[null,"FBgn0005771","no ocelli","noc","The gene no ocelli is referred to in FlyBase by the symbol Dmel\\noc (CG4491, FBgn0005771). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:14490862..14494019. It has the cytological map location 35B2. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior; eye-antennal disc development; cell proliferation; open tracheal system development. 55 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: peripheral nervous system; nervous system; organ system; adult segment; embryonic/larval tracheal system; integumentary plate; adult mesothoracic segment; embryonic dorsal branch; adult brain; adult external prothorax; embryonic ganglionic branch; postalar bristle. It has one annotated transcript and one annotated polypeptide.","regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> cell proliferation ; GO:0008283 | inferred from genetic interaction with elB <newline> eye-antennal disc development ; GO:0035214 | inferred from genetic interaction with elB <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0005775","Connectin","Con","The gene Connectin is referred to in FlyBase by the symbol Dmel\\Con (CG7503, FBgn0005775). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4938048..4976172. It has the cytological map location 64C2-64C4. Its molecular function is unknown. It is reported to be involved in the biological process</span>: homophilic cell adhesion; axonal fasciculation; cell adhesion; synaptic target attraction. 14 alleles are reported. The phenotypes of these alleles are annotated with 37 unique terms, many of which group under: hypodermal muscle of larval abdomen; abdominal oblique muscle; organ system; larval abdominal segment 5; abdominal ventral oblique muscle 4; hypodermal muscle of larval abdominal 2; abdominal 7 longitudinal muscle; embryonic neuron; abdominal segment 7; abdominal 6 longitudinal muscle. It has one annotated transcript and one annotated polypeptide.","cell adhesion ; GO:0007155 | non-traceable author statement <newline> axonal fasciculation ; GO:0007413 | traceable author statement <newline> homophilic cell adhesion ; GO:0007156 | traceable author statement <newline> synaptic target attraction ; GO:0016200 | traceable author statement <newline> homophilic cell adhesion ; GO:0007156 | non-traceable author statement","plasma membrane ; GO:0005886 | traceable author statement","-"]
[null,"FBgn0010113","headcase","hdc","The gene headcase is referred to in FlyBase by the symbol Dmel\\hdc (CG15532, FBgn0010113). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26103656..26187891. It has the cytological map location 99E4-99F1. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: RNA interference; axon extension involved in development. 46 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; adult segment; anatomical structure; thoracic segment; portion of tissue; tracheal system; adult; integumentary system; region of integument; nervous system; antennal segment. It has 3 annotated transcripts and 3 annotated polypeptides.","negative regulation of terminal cell fate specification, open tracheal system ; GO:0035155 | traceable author statement <newline> terminal branching, open tracheal system ; GO:0007430 | non-traceable author statement <newline> cell differentiation ; GO:0030154 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | non-traceable author statement <newline> terminal branching, open tracheal system ; GO:0007430 | traceable author statement <newline> branch fusion, open tracheal system ; GO:0035147 | traceable author statement <newline> RNA interference ; GO:0016246 | inferred from mutant phenotype <newline> axon extension involved in development ; GO:0048676 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | traceable author statement","molecular_function ; GO:0003674 | no biological data available"]
[null,"FBgn0010300","brain tumor","brat","The gene brain tumor is referred to in FlyBase by the symbol Dmel\\brat (CG10719, FBgn0010300). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:19133806..19172572. It has the cytological map location 37C1-37C6. There is experimental evidence that it has the molecular function</span>: protein binding; translation repressor activity. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; cell division; cellular macromolecule metabolic process; stem cell differentiation; regulation of biological process; transport; ncRNA metabolic process; neuroblast fate commitment; regionalization; biopolymer biosynthetic process; reproductive process in a multicellular organism; regulation of neurogenesis; neuron differentiation; regulation of metabolic process. 100 alleles are reported. The phenotypes of these alleles are annotated with: eye; neuron; 1st posterior cell; embryonic abdomen; adult thorax; embryonic epidermis; imaginal disc; embryonic/larval brain; ganglion mother cell; embryonic abdominal segment. It has 3 annotated transcripts and 3 annotated polypeptides.","rRNA metabolic process ; GO:0016072 | inferred from mutant phenotype <newline> rRNA transcription ; GO:0009303 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> negative regulation of cell proliferation ; GO:0008285 | inferred from mutant phenotype <newline> brain development ; GO:0007420 | inferred from mutant phenotype <newline> asymmetric cell division ; GO:0008356 | inferred from mutant phenotype <newline> negative regulation of neuroblast proliferation ; GO:0007406 | inferred from mutant phenotype <newline> ganglion mother cell fate determination ; GO:0007402 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | non-traceable author statement <newline> regulation of translation ; GO:0006417 | inferred from mutant phenotype <newline> regulation of translation ; GO:0006417 | traceable author statement <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> asymmetric neuroblast division resulting in ganglion mother cell formation ; GO:0055060 | inferred from mutant phenotype <newline> neuron differentiation ; GO:0030182 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay <newline> basal cortex ; GO:0045180 | colocalizes_with inferred from direct assay <newline> apical cortex ; GO:0045179 | colocalizes_with inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with nos <newline> translation repressor activity ; GO:0030371 | inferred from mutant phenotype <newline> translation regulator activity ; GO:0045182 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with 4EHP <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000315"]
[null,"FBgn0010313","corto","corto","The gene corto is referred to in FlyBase by the symbol Dmel\\corto (CG2530, FBgn0010313). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:909343..912408. It has the cytological map location 82E7. There is experimental evidence that it has the molecular function</span>: protein binding; identical protein binding; protein homodimerization activity. It is reported to be involved in the biological process</span>: chromatin silencing. 25 alleles are reported. The phenotypes of these alleles are annotated with 24 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; nervous system; adult external prothorax; embryonic/larval hemocoel; metatarsus; hemocyte; cell part; podocyte; endocrine system; imaginal precursor; external compound sense organ; antennal segment. It has one annotated transcript and one annotated polypeptide.","chromatin silencing ; GO:0006342 | inferred by curator from GO:0035102 inferred by curator from GO:0035098","centrosome ; GO:0005813 | non-traceable author statement <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> polytene chromosome ; GO:0005700 | inferred from direct assay <newline> ESC/E(Z) complex ; GO:0035098 | inferred from physical interaction with UniProtKB:Q24338 inferred from physical interaction with UniProtKB:P42124 <newline> PRC1 complex ; GO:0035102 | inferred from physical interaction with UniProtKB:Q9VHA0 inferred from physical interaction with UniProtKB:P39769","RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> protein binding ; GO:0005515 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with UniProtKB:P39769 inferred from physical interaction with UniProtKB:P42124 inferred from physical interaction with UniProtKB:Q08605 inferred from physical interaction with UniProtKB:Q24338 inferred from physical interaction with UniProtKB:Q9VHA0 <newline> identical protein binding ; GO:0042802 | inferred from physical interaction with UniProtKB:P41046 <newline> protein homodimerization activity ; GO:0042803 | inferred from physical interaction with UniProtKB:P41046"]
[null,"FBgn0010379","Akt1","Akt1","The gene Akt1 is referred to in FlyBase by the symbol Dmel\\Akt1 (CG4006, FBgn0010379). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11924938..11930239. It has the cytological map location 89B3. There is experimental evidence that it has the molecular function</span>: protein serine/threonine kinase activity; protein kinase activity. There is experimental evidence for 13 unique biological process</span> terms, many of which group under: regulation of biological process; regulation of developmental process; anatomical structure development; regulation of anatomical structure size; positive regulation of biological process; GO:0023034; biopolymer modification; lipid storage; regulation of apoptosis; regulation of neurogenesis; response to hormone stimulus. 30 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; organ system; external compound sense organ; adult mesothoracic segment; peripheral nervous system; thoracic segment; nervous system; wing hair; dorsal thoracic disc; synapse; embryonic trachea. It has 3 annotated transcripts and 3 annotated polypeptides.","anti-apoptosis ; GO:0006916 | inferred from mutant phenotype <newline> positive regulation of cell size ; GO:0045793 | inferred from mutant phenotype <newline> positive regulation of multicellular organism growth ; GO:0040018 | traceable author statement <newline> positive regulation of cell growth ; GO:0030307 | traceable author statement <newline> regulation of organ growth ; GO:0046620 | non-traceable author statement <newline> positive regulation of cell size ; GO:0045793 | traceable author statement <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> positive regulation of cell size ; GO:0045793 | non-traceable author statement <newline> positive regulation of organ growth ; GO:0046622 | non-traceable author statement <newline> insulin receptor signaling pathway ; GO:0008286 | non-traceable author statement <newline> positive regulation of cell growth ; GO:0030307 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> positive regulation of organ growth ; GO:0046622 | traceable author statement <newline> insulin receptor signaling pathway ; GO:0008286 | traceable author statement <newline> regulation of multicellular organism growth ; GO:0040014 | non-traceable author statement <newline> regulation of cell size ; GO:0008361 | non-traceable author statement <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from genetic interaction with Pi3K21B <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> regulation of protein import into nucleus ; GO:0042306 | traceable author statement <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> lipid storage ; GO:0019915 | inferred from genetic interaction with Pten <newline> positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype <newline> insulin receptor signaling pathway ; GO:0008286 | inferred from genetic interaction with UniProtKB:P91634 <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay <newline> regulation of dendrite development ; GO:0050773 | inferred from mutant phenotype <newline> regulation of multicellular organism growth ; GO:0040014 | inferred from mutant phenotype <newline> positive regulation of organ growth ; GO:0046622 | inferred from mutant phenotype <newline> intracellular signaling pathway ; GO:0023034 | inferred from genetic interaction with UniProtKB:P91634","plasma membrane ; GO:0005886 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> cell surface ; GO:0009986 | inferred from direct assay","protein kinase activity ; GO:0004672 | inferred from direct assay <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from mutant phenotype <newline> protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement <newline> phosphoinositide binding ; GO:0035091 | non-traceable author statement <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR000961, InterPro:IPR002290, InterPro:IPR015744, InterPro:IPR017441, InterPro:IPR017442, InterPro:IPR017892"]
[null,"FBgn0011591","fringe","fng","The gene fringe is referred to in FlyBase by the symbol Dmel\\fng (CG10580, FBgn0011591). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20918983..20942609. It has the cytological map location 78A1. There is experimental evidence that it has the molecular function</span>: UDP-glycosyltransferase activity; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity; acetylglucosaminyltransferase activity. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: anatomical structure development; organ development; organ morphogenesis; regulation of biological process; leg morphogenesis; sensory organ development; leg segmentation; biopolymer modification; hexose metabolic process; regionalization; appendage development; compound eye development. 66 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; peripheral nervous system; female germline cyst; late extended germ band embryo; nervous system; ectoderm derivative; external compound sense organ; primordium. It has one annotated transcript and one annotated polypeptide.","imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> dorsal/ventral pattern formation, imaginal disc ; GO:0007450 | inferred from direct assay <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from direct assay <newline> leg joint morphogenesis ; GO:0035111 | inferred from mutant phenotype <newline> leg segmentation ; GO:0035286 | inferred from mutant phenotype <newline> Notch signaling pathway ; GO:0007219 | inferred from direct assay <newline> fucose metabolic process ; GO:0006004 | inferred from direct assay <newline> germarium-derived egg chamber formation ; GO:0007293 | inferred from mutant phenotype <newline> regulation of Notch signaling pathway ; GO:0008593 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> cuticle pattern formation ; GO:0035017 | inferred from mutant phenotype <newline> positive regulation of Notch signaling pathway ; GO:0045747 | non-traceable author statement <newline> Notch signaling pathway ; GO:0007219 | traceable author statement <newline> dorsal/ventral lineage restriction, imaginal disc ; GO:0007451 | traceable author statement <newline> regulation of Notch signaling pathway ; GO:0008593 | traceable author statement <newline> negative regulation of Notch signaling pathway ; GO:0045746 | non-traceable author statement <newline> regulation of Notch signaling pathway ; GO:0008593 | non-traceable author statement <newline> cell fate specification ; GO:0001708 | non-traceable author statement <newline> compound eye development ; GO:0048749 | inferred from direct assay <newline> oogenesis ; GO:0048477 | traceable author statement <newline> regulation of Notch signaling pathway ; GO:0008593 | inferred from direct assay <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> protein amino acid O-linked glycosylation ; GO:0006493 | inferred from mutant phenotype <newline> fucose metabolic process ; GO:0006004 | inferred from mutant phenotype","Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> Golgi apparatus ; GO:0005794 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | non-traceable author statement <newline> Golgi stack ; GO:0005795 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> Golgi apparatus ; GO:0005794 | traceable author statement <newline> integral to Golgi membrane ; GO:0030173 | inferred from electronic annotation with InterPro:IPR017374","UDP-glycosyltransferase activity ; GO:0008194 | inferred from direct assay <newline> acetylglucosaminyltransferase activity ; GO:0008375 | inferred from direct assay <newline> acetylglucosaminyltransferase activity ; GO:0008375 | non-traceable author statement <newline> acetylglucosaminyltransferase activity ; GO:0008375 | traceable author statement <newline> O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity ; GO:0033829 | inferred from direct assay"]
[null,"FBgn0011661","Moesin","Moe","The gene Moesin is referred to in FlyBase by the symbol Dmel\\Moe (CG10701, FBgn0011661). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8767636..8792343. It has the cytological map location 8B4-8B6. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: determination of left/right symmetry; olfactory behavior; oocyte anterior/posterior axis specification; actin cytoskeleton organization; establishment or maintenance of epithelial cell apical/basal polarity; establishment or maintenance of polarity of larval imaginal disc epithelium; rhabdomere membrane biogenesis; rhabdomere development; regulation of actin cytoskeleton organization; regulation of membrane potential in photoreceptor cell. 84 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; thoracic segment; imaginal precursor; embryonic hindgut; embryonic dorsal trunk; dorsal thoracic disc; external compound sense organ; neuron; embryonic foregut; peripheral nervous system. It has 10 annotated transcripts and 10 annotated polypeptides.","establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from mutant phenotype <newline> establishment or maintenance of polarity of larval imaginal disc epithelium ; GO:0016336 | inferred from mutant phenotype <newline> actin cytoskeleton organization ; GO:0030036 | inferred from mutant phenotype <newline> anterior/posterior pattern formation ; GO:0009952 | traceable author statement <newline> cytoskeleton organization ; GO:0007010 | traceable author statement <newline> establishment or maintenance of apical/basal cell polarity ; GO:0035088 | traceable author statement <newline> eye photoreceptor cell development ; GO:0042462 | traceable author statement <newline> morphogenesis of an epithelium ; GO:0002009 | traceable author statement <newline> pole plasm assembly ; GO:0007315 | traceable author statement <newline> pole plasm protein localization ; GO:0007318 | traceable author statement <newline> protein localization ; GO:0008104 | traceable author statement <newline> rhabdomere development ; GO:0042052 | inferred from mutant phenotype <newline> rhabdomere membrane biogenesis ; GO:0045313 | inferred from mutant phenotype <newline> actin filament-based process ; GO:0030029 | non-traceable author statement <newline> olfactory behavior ; GO:0042048 | inferred from mutant phenotype <newline> oocyte anterior/posterior axis specification ; GO:0007314 | inferred from mutant phenotype <newline> regulation of membrane potential in photoreceptor cell ; GO:0016057 | inferred from direct assay <newline> determination of left/right symmetry ; GO:0007368 | inferred from mutant phenotype <newline> regulation of actin cytoskeleton organization ; GO:0032956 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from direct assay <newline> fusome ; GO:0045169 | NOT inferred from direct assay <newline> subapical complex ; GO:0035003 | traceable author statement <newline> cytoplasm ; GO:0005737 | non-traceable author statement <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> adherens junction ; GO:0005912 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> cell cortex ; GO:0005938 | inferred from direct assay <newline> spindle ; GO:0005819 | colocalizes_with inferred from direct assay <newline> actin filament ; GO:0005884 | colocalizes_with inferred from direct assay <newline> extrinsic to membrane ; GO:0019898 | inferred from electronic annotation with InterPro:IPR000798, InterPro:IPR008954, InterPro:IPR011174, InterPro:IPR011259","protein binding ; GO:0005515 | inferred from physical interaction with Mer <newline> cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity <newline> actin binding ; GO:0003779 | non-traceable author statement <newline> cytoskeletal protein binding ; GO:0008092 | inferred from electronic annotation with InterPro:IPR000798, InterPro:IPR008954, InterPro:IPR011174, InterPro:IPR011259"]
[null,"FBgn0011766","E2F transcription factor","E2f","The gene E2F transcription factor is referred to in FlyBase by the symbol Dmel\\E2f (CG6376, FBgn0011766). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17446026..17486127. It has the cytological map location 93E9-93F1. There is experimental evidence that it has the molecular function</span>: protein binding; RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of gene expression; cellular process; dendrite morphogenesis; neuron development; positive regulation of nurse cell apoptosis; muscle tissue development; antimicrobial humoral response; regulation of cell cycle; DNA endoreduplication. 70 alleles are reported. The phenotypes of these alleles are annotated with 31 unique terms, many of which group under: organ system; peripheral nervous system; nervous system; external compound sense organ; female germline cyst; egg; imaginal precursor; adult segment; cell part; primordium; adult mesothoracic segment. It has 3 annotated transcripts and 3 annotated polypeptides.","positive regulation of cell proliferation ; GO:0008284 | non-traceable author statement <newline> positive regulation of nurse cell apoptosis ; GO:0045850 | inferred from mutant phenotype <newline> DNA endoreduplication ; GO:0042023 | inferred from genetic interaction with CycE AND inferred from mutant phenotype <newline> eggshell chorion gene amplification ; GO:0007307 | traceable author statement <newline> G1/S transition of mitotic cell cycle ; GO:0000082 | traceable author statement <newline> imaginal disc development ; GO:0007444 | traceable author statement <newline> nurse cell apoptosis ; GO:0045476 | traceable author statement <newline> positive regulation of transcription ; GO:0045941 | traceable author statement <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> regulation of transcription involved in G1/S-phase of mitotic cell cycle ; GO:0000083 | non-traceable author statement <newline> growth ; GO:0040007 | non-traceable author statement <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | inferred from mutant phenotype <newline> regulation of cell cycle ; GO:0051726 | non-traceable author statement <newline> positive regulation of gene expression ; GO:0010628 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> muscle tissue development ; GO:0060537 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR003316","nucleus ; GO:0005634 | inferred from direct assay <newline> Rb-E2F complex ; GO:0035189 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","DNA binding ; GO:0003677 | inferred from direct assay <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from physical interaction with Rbf <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription activator activity ; GO:0016563 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with dom inferred from physical interaction with l(3)mbt <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR003316"]
[null,"FBgn0014184","Ornithine decarboxylase antizyme","Oda","The gene Ornithine decarboxylase antizyme is referred to in FlyBase by the symbol Dmel\\Oda (CG16747, FBgn0014184). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8054077..8061767. It has the cytological map location 48E4. Based on sequence similarity, it is predicted to have molecular function</span>: ornithine decarboxylase inhibitor activity. It is reported to be involved in the biological process</span>: cell differentiation. 25 alleles are reported. The phenotypes of these alleles are annotated with: larval salivary gland; lymph gland; dorsal mesothoracic disc; dorsal metathoracic disc; imaginal disc; embryonic/larval brain; ventral thoracic disc; salivary gland imaginal ring. It has 3 annotated transcripts and 3 annotated polypeptides.","cell differentiation ; GO:0030154 | non-traceable author statement","-","ornithine decarboxylase inhibitor activity ; GO:0008073 | inferred from sequence or structural similarity with HGNC_gene:OAZ1; HGNC:8095; OMIM:601579 <newline> ornithine decarboxylase inhibitor activity ; GO:0008073 | non-traceable author statement"]
[null,"FBgn0015218","Eukaryotic initiation factor 4E","eIF-4E","The gene Eukaryotic initiation factor 4E is referred to in FlyBase by the symbol Dmel\\eIF-4E (CG4035, FBgn0015218). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9392716..9395565. It has the cytological map location 67B4. There is experimental evidence that it has the molecular function</span>: translation initiation factor activity; RNA cap binding. There is experimental evidence for 11 unique biological process</span> terms, many of which group under: cell cycle; cell cycle process; organelle organization; programmed cell death; cellular macromolecule metabolic process; nuclear division; biopolymer biosynthetic process; gland morphogenesis; chromatin organization; cell death; chromosome organization; regulation of biological process. 38 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: nervous system; organ system; peripheral nervous system; external compound sense organ; thoracic segment; cell component; cell cycle; dorsal thoracic disc; multi-cell-component structure; eipithelial furrow; neuromuscular junction; adult segment. It has 7 annotated transcripts and 7 annotated polypeptides.","translation ; GO:0006412 | inferred from sequence or structural similarity with HGNC_gene:EIF4E; HGNC:3287; OMIM:133440 AND inferred from sequence or structural similarity with MGD:Eif4e; MGI:MGI:95305 <newline> RNA metabolic process ; GO:0016070 | inferred from direct assay <newline> translational initiation ; GO:0006413 | inferred from direct assay <newline> translation ; GO:0006412 | non-traceable author statement <newline> positive regulation of cell growth ; GO:0030307 | traceable author statement <newline> regulation of cell growth ; GO:0001558 | inferred from mutant phenotype <newline> RNA metabolic process ; GO:0016070 | non-traceable author statement <newline> translational initiation ; GO:0006413 | non-traceable author statement <newline> chromatin organization ; GO:0006325 | inferred from mutant phenotype <newline> female meiosis chromosome segregation ; GO:0016321 | inferred from mutant phenotype <newline> mitosis ; GO:0007067 | inferred from mutant phenotype <newline> mitotic chromosome condensation ; GO:0007076 | inferred from mutant phenotype <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype","cytosol ; GO:0005829 | inferred from sequence or structural similarity with HGNC_gene:EIF4E; HGNC:3287; OMIM:133440 AND inferred from sequence or structural similarity with MGD:Eif4e; MGI:MGI:95305 <newline> eukaryotic translation initiation factor 4F complex ; GO:0016281 | non-traceable author statement <newline> cytosol ; GO:0005829 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> cytosol ; GO:0005829 | inferred from sequence or structural similarity <newline> eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity <newline> postsynaptic density ; GO:0014069 | inferred from direct assay <newline> cytoplasmic mRNA processing body ; GO:0000932 | inferred from direct assay <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with HGNC_gene:EIF4E; HGNC:3287; OMIM:133440 AND inferred from sequence or structural similarity with MGD:Eif4e; MGI:MGI:95305 <newline> RNA cap binding ; GO:0000339 | inferred from direct assay <newline> translation initiation factor activity ; GO:0003743 | inferred from direct assay <newline> translation initiation factor activity ; GO:0003743 | non-traceable author statement <newline> RNA cap binding ; GO:0000339 | inferred from sequence or structural similarity <newline> translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity <newline> RNA cap binding ; GO:0000339 | non-traceable author statement"]
[null,"FBgn0015229","gliolectin","glec","The gene gliolectin is referred to in FlyBase by the symbol Dmel\\glec (CG6575, FBgn0015229). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17676627..17681984. It has the cytological map location 93F14. There is experimental evidence that it has the molecular function</span>: carbohydrate binding. There is experimental evidence that it is involved in the biological process</span>: heterophilic cell adhesion; nervous system development. 19 alleles are reported. The phenotypes of these alleles are annotated with: ventral nerve cord commissure; trichogen cell; macrochaeta; pCC neuron; scutellar bristle. It has one annotated transcript and one annotated polypeptide.","heterophilic cell-cell adhesion ; GO:0007157 | inferred from mutant phenotype <newline> cell adhesion ; GO:0007155 | non-traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> nervous system development ; GO:0007399 | inferred from expression pattern AND inferred from mutant phenotype","integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> membrane fraction ; GO:0005624 | inferred from direct assay","carbohydrate binding ; GO:0030246 | inferred from direct assay <newline> carbohydrate binding ; GO:0030246 | non-traceable author statement"]
[null,"FBgn0015790","Rab-protein 11","Rab11","The gene Rab-protein 11 is referred to in FlyBase by the symbol Dmel\\Rab11 (CG5771, FBgn0015790). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16937129..16941877. It has the cytological map location 93B12-93B13. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. There is experimental evidence for 18 unique biological process</span> terms, many of which group under: anatomical structure development; sensory organ development; reproductive process in a multicellular organism; cell division; organ morphogenesis; cell cycle; organelle organization; transport; regulation of cellular component organization; contractile ring contraction involved in cytokinesis during cell cycle; immune response; synaptic transmission; regulation of developmental process; vesicle fusion; actin filament-based process. 44 alleles are reported. The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: peripheral nervous system; nervous system; external compound sense organ; adult segment; cytoplasmic part; organ system; adult mesothoracic segment; intracellular membrane-bounded organelle; spindle; acroblast; rhabdomere; contractile ring; egg; cell division site; imaginal precursor; syncytial blastoderm embryo; garland cell; late extended germ band embryo. It has 2 annotated transcripts and 2 annotated polypeptides.","regulation of pole plasm oskar mRNA localization ; GO:0007317 | inferred from mutant phenotype <newline> endocytosis ; GO:0006897 | inferred from mutant phenotype <newline> oocyte microtubule cytoskeleton polarization ; GO:0008103 | inferred from mutant phenotype <newline> actin cytoskeleton reorganization ; GO:0031532 | inferred from mutant phenotype <newline> rhabdomere development ; GO:0042052 | inferred from mutant phenotype <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> cellularization ; GO:0007349 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from genetic interaction with bchs <newline> bristle development ; GO:0022416 | inferred from mutant phenotype <newline> regulation of synapse organization ; GO:0050807 | inferred from mutant phenotype <newline> endocytosis ; GO:0006897 | inferred from direct assay <newline> sensory organ precursor cell fate determination ; GO:0016360 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype <newline> male meiosis cytokinesis ; GO:0007112 | inferred from mutant phenotype <newline> spermatocyte division ; GO:0048137 | inferred from mutant phenotype <newline> contractile ring contraction involved in cell cycle cytokinesis ; GO:0000916 | inferred from mutant phenotype <newline> Golgi vesicle fusion to target membrane ; GO:0048210 | inferred from mutant phenotype <newline> small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579 <newline> protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR003579","trans-Golgi network transport vesicle ; GO:0030140 | inferred from direct assay <newline> terminal button ; GO:0043195 | inferred from direct assay <newline> centrosome ; GO:0005813 | colocalizes_with inferred from direct assay <newline> endosome ; GO:0005768 | inferred from direct assay <newline> lipid particle ; GO:0005811 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> vesicle ; GO:0031982 | inferred from direct assay <newline> cell pole ; GO:0060187 | inferred from direct assay <newline> cleavage furrow ; GO:0032154 | inferred from direct assay <newline> Golgi apparatus ; GO:0005794 | inferred from direct assay <newline> spindle envelope ; GO:0070732 | inferred from direct assay <newline> nuclear envelope ; GO:0005635 | inferred from direct assay <newline> perinuclear region of cytoplasm ; GO:0048471 | inferred from direct assay","GTPase activity ; GO:0003924 | inferred from sequence or structural similarity <newline> GTP binding ; GO:0005525 | non-traceable author statement <newline> GTPase activity ; GO:0003924 | non-traceable author statement <newline> GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225"]
[null,"FBgn0016059","Sema-1b","Sema-1b","The gene Sema-1b is referred to in FlyBase by the symbol Dmel\\Sema-1b (CG6446, FBgn0016059). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13560344..13571000. It has the cytological map location 54D4-54D5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: receptor activity. There is experimental evidence that it is involved in the biological process</span>: embryonic development via the syncytial blastoderm. 9 alleles are reported. The phenotype of these alleles is annotated with: intersegmental nerve. It has 3 annotated transcripts and 3 annotated polypeptides.","axon guidance ; GO:0007411 | inferred from sequence or structural similarity with EMBL:AF036585 <newline> embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from expression pattern","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with EMBL:AF036585","receptor activity ; GO:0004872 | inferred from electronic annotation with InterPro:IPR016201"]
[null,"FBgn0016797","frizzled 2","fz2","The gene frizzled 2 is referred to in FlyBase by the symbol Dmel\\fz2 (CG9739, FBgn0016797). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19135998..19228191. It has the cytological map location 75F9-76A3. There is experimental evidence that it has the molecular function</span>: Wnt receptor activity; protein binding; PDZ domain binding; Wnt-protein binding. There is experimental evidence that it is involved in the biological process</span>: female gonad development; cellular component movement; imaginal disc-derived wing margin morphogenesis; receptor-mediated endocytosis; bristle morphogenesis; Wnt receptor signaling pathway; axon extension; salivary gland morphogenesis; Wnt receptor signaling pathway, calcium modulating pathway; synapse organization. 112 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; adult segment; nervous system; adult mesothoracic segment; external compound sense organ; peripheral nervous system; cell component; cuticle; t-bar; embryonic neuron; postsynaptic membrane; neuromuscular junction. It has 4 annotated transcripts and 4 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from direct assay <newline> establishment or maintenance of cell polarity ; GO:0007163 | inferred from sequence or structural similarity <newline> Wnt receptor signaling pathway, calcium modulating pathway ; GO:0007223 | inferred from direct assay <newline> cellular component movement ; GO:0006928 | inferred from mutant phenotype <newline> female gonad development ; GO:0008585 | inferred from mutant phenotype <newline> bristle morphogenesis ; GO:0008407 | inferred from mutant phenotype <newline> receptor-mediated endocytosis ; GO:0006898 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from sequence or structural similarity <newline> Wnt receptor signaling pathway ; GO:0016055 | non-traceable author statement <newline> axon extension ; GO:0048675 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> synapse organization ; GO:0050808 | inferred from physical interaction with Grip <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype","integral to membrane ; GO:0016021 | non-traceable author statement <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> early endosome ; GO:0005769 | colocalizes_with inferred from direct assay <newline> plasma membrane ; GO:0005886 | inferred from direct assay <newline> late endosome ; GO:0005770 | colocalizes_with inferred from direct assay","Wnt receptor activity ; GO:0042813 | inferred from direct assay <newline> Wnt-protein binding ; GO:0017147 | inferred from direct assay <newline> protein binding ; GO:0005515 | inferred from direct assay <newline> transmembrane receptor activity ; GO:0004888 | inferred from sequence or structural similarity <newline> Wnt receptor activity ; GO:0042813 | non-traceable author statement <newline> PDZ domain binding ; GO:0030165 | inferred from physical interaction with Grip <newline> non-G-protein coupled 7TM receptor activity ; GO:0004926 | inferred from electronic annotation with InterPro:IPR000539"]
[null,"FBgn0017590","klingon","klg","The gene klingon is referred to in FlyBase by the symbol Dmel\\klg (CG6669, FBgn0017590). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:18725024..18787456. It has the cytological map location 94D3-94D4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: olfactory learning; learning or memory; homophilic cell adhesion; long-term memory; R7 cell differentiation; R7 cell fate commitment. 25 alleles are reported. The phenotypes of these alleles are annotated with: photoreceptor cell R7; photoreceptor cell; ommatidium. It has one annotated transcript and one annotated polypeptide.","R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype <newline> R7 cell fate commitment ; GO:0007465 | inferred from genetic interaction with sev, Sos <newline> homophilic cell adhesion ; GO:0007156 | inferred from direct assay <newline> learning or memory ; GO:0007611 | inferred from mutant phenotype <newline> olfactory learning ; GO:0008355 | inferred from mutant phenotype <newline> long-term memory ; GO:0007616 | inferred from mutant phenotype <newline> anesthesia-resistant memory ; GO:0007615 | NOT inferred from mutant phenotype","extrinsic to plasma membrane ; GO:0019897 | inferred from sequence or structural similarity","-"]
[null,"FBgn0020278","locomotion defects","loco","The gene locomotion defects is referred to in FlyBase by the symbol Dmel\\loco (CG5248, FBgn0020278). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:18445690..18465082. It has the cytological map location 94B6-94B8. There is experimental evidence that it has the molecular function</span>: G-protein alpha-subunit binding; GTPase activator activity. There is experimental evidence that it is involved in the biological process</span>: regulation of G-protein coupled receptor protein signaling pathway; glial cell differentiation; asymmetric neuroblast division; asymmetric protein localization; dorsal/ventral axis specification, ovarian follicular epithelium; establishment of glial blood-brain barrier; cytoplasmic transport, nurse cell to oocyte; cortical actin cytoskeleton organization; septate junction assembly; ventral cord development. 34 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; yolk; embryonic head; embryonic glial cell; neuroblast; embryonic midgut; egg; longitudinal connective; embryonic foregut; dorsal appendage. It has 4 annotated transcripts and 4 annotated polypeptides.","glial cell differentiation ; GO:0010001 | inferred from mutant phenotype <newline> regulation of G-protein coupled receptor protein signaling pathway ; GO:0008277 | non-traceable author statement <newline> cytoplasmic transport, nurse cell to oocyte ; GO:0007303 | inferred from mutant phenotype <newline> dorsal/ventral axis specification, ovarian follicular epithelium ; GO:0008069 | inferred from mutant phenotype <newline> asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype <newline> regulation of G-protein coupled receptor protein signaling pathway ; GO:0008277 | inferred from genetic interaction with raps <newline> asymmetric protein localization ; GO:0008105 | inferred from mutant phenotype <newline> septate junction assembly ; GO:0019991 | inferred from mutant phenotype <newline> establishment of glial blood-brain barrier ; GO:0060857 | inferred from mutant phenotype <newline> ventral cord development ; GO:0007419 | inferred from mutant phenotype <newline> cortical actin cytoskeleton organization ; GO:0030866 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR003109, InterPro:IPR003116","plasma membrane ; GO:0005886 | colocalizes_with inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> apical cortex ; GO:0045179 | inferred from direct assay","GTPase activator activity ; GO:0005096 | inferred from direct assay <newline> G-protein alpha-subunit binding ; GO:0001965 | inferred from physical interaction with G-iÎ±65A <newline> receptor signaling protein activity ; GO:0005057 | inferred from electronic annotation with InterPro:IPR003116"]
[null,"FBgn0020513","ade5","ade5","The gene ade5 is referred to in FlyBase by the symbol Dmel\\ade5 (CG3989, FBgn0020513). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:12651793..12654651. It has the cytological map location 11B16. Based on sequence similarity, it is predicted to have molecular function</span>: phosphoribosylaminoimidazolesuccinocarboxamide synthase activity; phosphoribosylaminoimidazole carboxylase activity. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior. 13 alleles are reported. The phenotype of these alleles is annotated with: pigment cell. It has one annotated transcript and one annotated polypeptide.","inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype <newline> 'de novo' IMP biosynthetic process ; GO:0006189 | inferred from electronic annotation with InterPro:IPR000031","-","phosphoribosylaminoimidazole carboxylase activity ; GO:0004638 | inferred from sequence or structural similarity <newline> phosphoribosylaminoimidazolesuccinocarboxamide synthase activity ; GO:0004639 | inferred from sequence or structural similarity <newline> phosphoribosylaminoimidazole carboxylase activity ; GO:0004638 | inferred from sequence or structural similarity with UniProtKB:P51583 <newline> phosphoribosylaminoimidazolesuccinocarboxamide synthase activity ; GO:0004639 | inferred from sequence or structural similarity with UniProtKB:P51583 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR013816"]
[null,"FBgn0022720","Zinc finger protein 30C","zf30C","The gene Zinc finger protein 30C is referred to in FlyBase by the symbol Dmel\\zf30C (CG3998, FBgn0022720). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:9758338..9762377. It has the cytological map location 30C7. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: neuron development. 6 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; wing margin; posterior crossvein; wing; wing vein L2. It has one annotated transcript and one annotated polypeptide.","neuron development ; GO:0048666 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:U27186","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with EMBL:U27186 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0023001","melted","melt","The gene melted is referred to in FlyBase by the symbol Dmel\\melt (CG8624, FBgn0023001). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:7127618..7136174. It has the cytological map location 65E4-65E5. There is experimental evidence that it has the molecular function</span>: specific transcriptional repressor activity; phosphoinositide binding; phosphatidylinositol-5-phosphate binding. There is experimental evidence that it is involved in the biological process</span>: insulin receptor signaling pathway; ectoderm development; sequestering of triglyceride; R8 cell fate specification; peripheral nervous system development. 17 alleles are reported. The phenotypes of these alleles are annotated with: photoreceptor cell R8 of yellow ommatidium; embryonic peripheral nervous system; embryonic nervous system; wing. It has 2 annotated transcripts and 2 annotated polypeptides.","sequestering of triglyceride ; GO:0030730 | inferred from mutant phenotype <newline> insulin receptor signaling pathway ; GO:0008286 | inferred from mutant phenotype <newline> ectoderm development ; GO:0007398 | inferred from expression pattern <newline> peripheral nervous system development ; GO:0007422 | inferred from mutant phenotype <newline> R8 cell fate specification ; GO:0045464 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from direct assay","phosphoinositide binding ; GO:0035091 | inferred from direct assay <newline> phosphatidylinositol-5-phosphate binding ; GO:0010314 | inferred from direct assay <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype"]
[null,"FBgn0023095","capricious","caps","The gene capricious is referred to in FlyBase by the symbol Dmel\\caps (CG11282, FBgn0023095). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:13221789..13272742. It has the cytological map location 70A3-70A4. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: axon guidance; open tracheal system development; branch fusion, open tracheal system. 59 alleles are reported. The phenotypes of these alleles are annotated with: embryonic dorsal trunk; leg; macrochaeta; motor neuron; abdominal RP5 neuron; embryonic lateral trunk; ventral thoracic disc; transverse nerve; axon. It has 3 annotated transcripts and 3 annotated polypeptides.","axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> cell adhesion ; GO:0007155 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> cell migration ; GO:0016477 | traceable author statement <newline> branch fusion, open tracheal system ; GO:0035147 | inferred from mutant phenotype","membrane ; GO:0016020 | non-traceable author statement <newline> cell projection ; GO:0042995 | inferred from direct assay","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR001611"]
[null,"FBgn0024250","brinker","brk","The gene brinker is referred to in FlyBase by the symbol Dmel\\brk (CG9653, FBgn0024250). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7201974..7205165. It has the cytological map location 7B1. There is experimental evidence that it has the molecular function</span>: specific transcriptional repressor activity. There is experimental evidence that it is involved in the biological process</span>: wing disc morphogenesis; cell competition in a multicellular organism; negative regulation of transforming growth factor beta receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; imaginal disc-derived wing morphogenesis. 65 alleles are reported. The phenotypes of these alleles are annotated with 36 unique terms, many of which group under: organ system; primordium; adult segment; embryonic nervous system; adult mesothoracic segment; ventral nerve cord primordium; portion of tissue; somatic stem cell; peripheral nervous system; thoracic segment. It has one annotated transcript and one annotated polypeptide.","negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | inferred from mutant phenotype <newline> negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | inferred from mutant phenotype <newline> wing disc morphogenesis ; GO:0007472 | inferred from mutant phenotype <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | traceable author statement <newline> transforming growth factor beta receptor signaling pathway ; GO:0007179 | traceable author statement <newline> regulation of BMP signaling pathway ; GO:0030510 | traceable author statement <newline> salivary gland boundary specification ; GO:0007432 | non-traceable author statement <newline> negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | non-traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> cell competition in a multicellular organism ; GO:0035212 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with dsx <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | traceable author statement <newline> specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype"]
[null,"FBgn0024555","falafel","flfl","The gene falafel is referred to in FlyBase by the symbol Dmel\\flfl (CG9351, FBgn0024555). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:9509680..9519629. It has the cytological map location 87F10-87F11. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: Rac protein signal transduction; dorsal closure; neuroblast proliferation; phagocytosis, engulfment. 20 alleles are reported. The phenotypes of these alleles are annotated with: neuroblast; wing; cell; wing vein. It has 2 annotated transcripts and 2 annotated polypeptides.","Rac protein signal transduction ; GO:0016601 | inferred from genetic interaction with Rac1 <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype <newline> asymmetric neuroblast division ; GO:0055059 | inferred from electronic annotation <newline> neuroblast proliferation ; GO:0007405 | inferred from mutant phenotype","-","-"]
[null,"FBgn0025463","Brahma associated protein 60kD","Bap60","The gene Brahma associated protein 60kD is referred to in FlyBase by the symbol Dmel\\Bap60 (CG4303, FBgn0025463). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:13051478..13053611. It has the cytological map location 11E1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis; neuron development; muscle organ development; positive regulation of transcription, DNA-dependent. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","positive regulation of transcription, DNA-dependent ; GO:0045893 | inferred from direct assay <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype","brahma complex ; GO:0035060 | inferred from direct assay <newline> chromatin remodeling complex ; GO:0016585 | inferred from sequence or structural similarity with EMBL:U66620","transcription coactivator activity ; GO:0003713 | contributes_to inferred by curator from GO:0035060 <newline> protein binding ; GO:0005515 | inferred from physical interaction with mor <newline> general RNA polymerase II transcription factor activity ; GO:0016251 | inferred from sequence or structural similarity with EMBL:U66620 <newline> protein binding ; GO:0005515 | inferred from physical interaction with Myo10A"]
[null,"FBgn0026479","Dynamin related protein 1","Drp1","The gene Dynamin related protein 1 is referred to in FlyBase by the symbol Dmel\\Drp1 (CG3210, FBgn0026479). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:2581437..2585448. It has the cytological map location 23A1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: GTP binding; GTPase activity. There is experimental evidence that it is involved in the biological process</span>: lysosome organization; sperm mitochondrion organization; mitochondrion localization; intracellular distribution of mitochondria; cytokinesis; vesicle organization; mitochondrion organization; negative regulation of autophagy. 20 alleles are reported. The phenotypes of these alleles are annotated with: larval neuromuscular junction; ventral furrow. It has one annotated transcript and one annotated polypeptide.","synaptic vesicle budding from presynaptic membrane ; GO:0016185 | non-traceable author statement <newline> intracellular distribution of mitochondria ; GO:0048312 | inferred from mutant phenotype <newline> mitochondrion organization ; GO:0007005 | inferred from mutant phenotype <newline> vesicle organization ; GO:0016050 | inferred from mutant phenotype <newline> cytokinesis ; GO:0000910 | inferred from mutant phenotype <newline> sperm mitochondrion organization ; GO:0030382 | inferred from mutant phenotype <newline> mitochondrion localization ; GO:0051646 | inferred from mutant phenotype <newline> negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype <newline> lysosome organization ; GO:0007040 | inferred from mutant phenotype","microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity <newline> microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity with EMBL:AF019043 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000375, InterPro:IPR001401, InterPro:IPR003130 <newline> GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR001401, InterPro:IPR003130"]
[null,"FBgn0026575","hangover","hang","The gene hangover is referred to in FlyBase by the symbol Dmel\\hang (CG32575, FBgn0026575). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16316877..16331531. It has the cytological map location 14C4. Based on sequence similarity, it is predicted to have molecular function</span>: nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: behavioral response to ethanol. 8 alleles are reported. The phenotype of these alleles is annotated with: wing. It has 3 annotated transcripts and 3 annotated polypeptides.","response to ethanol ; GO:0045471 | non-traceable author statement <newline> response to heat ; GO:0009408 | non-traceable author statement <newline> response to stress ; GO:0006950 | non-traceable author statement <newline> behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay","nucleic acid binding ; GO:0003676 | inferred from sequence or structural similarity with UniProtKB:Q9UL36 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR012934, InterPro:IPR015880"]
[null,"FBgn0027108","innexin 2","inx2","The gene innexin 2 is referred to in FlyBase by the symbol Dmel\\inx2 (CG4590, FBgn0027108). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6892696..6898182. It has the cytological map location 6E4. It is reported to have molecular function</span>: gap junction channel activity. There is experimental evidence that it is involved in the biological process</span>: morphogenesis of embryonic epithelium; olfactory behavior; foregut morphogenesis. 41 alleles are reported. The phenotypes of these alleles are annotated with: embryonic hindgut; embryonic salivary gland; embryonic head; embryonic segment; proventriculus primordium; embryonic Malpighian tubule; embryonic/larval proventriculus; embryonic epidermis; embryonic tracheal system; embryonic foregut. It has 3 annotated transcripts and 3 annotated polypeptides.","foregut morphogenesis ; GO:0007440 | inferred from mutant phenotype <newline> morphogenesis of embryonic epithelium ; GO:0016331 | inferred from mutant phenotype <newline> olfactory behavior ; GO:0042048 | inferred from mutant phenotype","gap junction ; GO:0005921 | non-traceable author statement <newline> gap junction ; GO:0005921 | inferred from sequence or structural similarity with EMBL:AF115854; protein_id:AAD29306.1 <newline> integral to membrane ; GO:0016021 | non-traceable author statement <newline> gap junction ; GO:0005921 | inferred from direct assay","gap junction channel activity ; GO:0005243 | non-traceable author statement"]
[null,"FBgn0033422","Odorant receptor 45b","Or45b","The gene Odorant receptor 45b is referred to in FlyBase by the symbol Dmel\\Or45b (CG12931, FBgn0033422). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:5447103..5448573. It has the cytological map location 45F1. Based on sequence similarity, it is predicted to have molecular function</span>: olfactory receptor activity. There is experimental evidence that it is involved in the biological process</span>: detection of chemical stimulus involved in sensory perception of smell. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","sensory perception of smell ; GO:0007608 | inferred from sequence or structural similarity <newline> detection of chemical stimulus involved in sensory perception of smell ; GO:0050911 | inferred from mutant phenotype","integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR004117","olfactory receptor activity ; GO:0004984 | inferred from sequence or structural similarity <newline> olfactory receptor activity ; GO:0004984 | inferred from electronic annotation with InterPro:IPR004117 <newline> odorant binding ; GO:0005549 | inferred from electronic annotation with InterPro:IPR004117"]
[null,"FBgn0037645","-","CG11966","This gene is referred to in FlyBase by the symbol Dmel\\CG11966 (CG11966, FBgn0037645). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4777711..4788683. It has the cytological map location 85B8-85B9. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding; nucleic acid binding. The biological processes in which it is involved are not known. 14 alleles are reported. The phenotypes of these alleles are annotated with: ventral nerve cord commissure; eye; ventral nerve cord; ventral midline. It has one annotated transcript and one annotated polypeptide.","-","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087"]
[null,"FBgn0039350","jing interacting gene regulatory 1","jigr1","The gene jing interacting gene regulatory 1 is referred to in FlyBase by the symbol Dmel\\jigr1 (CG17383, FBgn0039350). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21463549..21475972. It has the cytological map location 96E6. Its molecular function is unknown. The biological processes in which it is involved are not known. 24 alleles are reported. The phenotypes of these alleles are annotated with: wing; larval central nervous system. It has 6 annotated transcripts and 6 annotated polypeptides.","-","-","-"]
[null,"FBgn0040283","SMC1","SMC1","The gene SMC1 is referred to in FlyBase by the symbol Dmel\\SMC1 (CG6057, FBgn0040283). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19884024..19888538. It has the cytological map location 95D11. Based on sequence similarity, it is predicted to have molecular function</span>: DNA binding. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis; negative regulation of gene expression; neuron remodeling; mushroom body development. 6 alleles are reported. The phenotype of these alleles is annotated with: condensed chromosome. It has one annotated transcript and one annotated polypeptide.","sister chromatid cohesion ; GO:0007062 | inferred from sequence or structural similarity with SGD_LOCUS:SMC1; SGD:S0001886 <newline> sister chromatid cohesion ; GO:0007062 | non-traceable author statement <newline> negative regulation of gene expression ; GO:0010629 | inferred from genetic interaction with ct <newline> mushroom body development ; GO:0016319 | inferred from mutant phenotype <newline> neuron remodeling ; GO:0016322 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype","cohesin complex ; GO:0008278 | non-traceable author statement <newline> cohesin complex ; GO:0008278 | inferred from sequence or structural similarity with SGD_LOCUS:SMC1; SGD:S0001886 <newline> cohesin complex ; GO:0008278 | inferred from sequence or structural similarity <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> cohesin complex ; GO:0008278 | inferred from direct assay <newline> chromosome ; GO:0005694 | colocalizes_with inferred from direct assay <newline> transcriptionally active chromatin ; GO:0035327 | inferred from direct assay","DNA binding ; GO:0003677 | inferred from sequence or structural similarity with SGD_LOCUS:SMC1; SGD:S0001886 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003395, InterPro:IPR010935 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR010935"]
[null,"FBgn0041092","taiman","tai","The gene taiman is referred to in FlyBase by the symbol Dmel\\tai (CG13109, FBgn0041092). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:9166802..9247187. It has the cytological map location 30A2-30A6. There is experimental evidence that it has the molecular function</span>: steroid hormone receptor binding; ligand-dependent nuclear receptor transcription coactivator activity. There is experimental evidence that it is involved in the biological process</span>: border follicle cell migration; axon extension involved in development. 57 alleles are reported. The phenotypes of these alleles are annotated with: border follicle cell; imaginal disc. It has 2 annotated transcripts and 2 annotated polypeptides.","border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with tgo <newline> axon extension involved in development ; GO:0048676 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR000014","nucleus ; GO:0005634 | inferred from direct assay <newline> ecdysone receptor holocomplex ; GO:0008230 | colocalizes_with inferred from direct assay","transcription coactivator activity ; GO:0003713 | inferred from sequence or structural similarity <newline> transcription coactivator activity ; GO:0003713 | non-traceable author statement <newline> steroid hormone receptor binding ; GO:0035258 | inferred from physical interaction with EcR <newline> ligand-dependent nuclear receptor transcription coactivator activity ; GO:0030374 | inferred from direct assay <newline> signal transducer activity ; GO:0004871 | inferred from electronic annotation with InterPro:IPR000014"]
[null,"FBgn0041604","dally-like","dlp","The gene dally-like is referred to in FlyBase by the symbol Dmel\\dlp (CG32146, FBgn0041604). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14625720..14664716. It has the cytological map location 70E5-70E7. It is reported to have molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; detection of light stimulus involved in visual perception; axon guidance; compound eye development; imaginal disc-derived wing margin morphogenesis; wing disc dorsal/ventral pattern formation; positive regulation of smoothened signaling pathway; Wnt receptor signaling pathway; regulation of imaginal disc growth; segment polarity determination. 39 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; peripheral nervous system; adult mesothoracic segment; external compound sense organ; organ system; nervous system; cuticle; lamina plexus; dorsal thoracic disc; compound cell cluster organ. It has 2 annotated transcripts and 2 annotated polypeptides.","Wnt receptor signaling pathway ; GO:0016055 | inferred from genetic interaction with dally AND inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> decapentaplegic receptor signaling pathway ; GO:0008101 | non-traceable author statement <newline> smoothened signaling pathway ; GO:0007224 | traceable author statement <newline> segment polarity determination ; GO:0007367 | inferred from mutant phenotype <newline> smoothened signaling pathway ; GO:0007224 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from expression pattern AND inferred from genetic interaction with wg <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> imaginal disc-derived wing margin morphogenesis ; GO:0008587 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> detection of light stimulus involved in visual perception ; GO:0050908 | inferred from mutant phenotype <newline> positive regulation of smoothened signaling pathway ; GO:0045880 | inferred from mutant phenotype <newline> regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype","extracellular region ; GO:0005576 | inferred from sequence or structural similarity <newline> proteinaceous extracellular matrix ; GO:0005578 | inferred from electronic annotation with InterPro:IPR001863 <newline> membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001863","protein binding ; GO:0005515 | non-traceable author statement <newline> heparan sulfate proteoglycan binding ; GO:0043395 | inferred from electronic annotation with InterPro:IPR001863"]
[null,"FBgn0052541","-","CG32541","This gene is referred to in FlyBase by the symbol Dmel\\CG32541 (CG32541, FBgn0052541). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:18824392..18920905. It has the cytological map location 17F3-18A2. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior. 25 alleles are reported. The phenotype of these alleles is annotated with: macrochaeta. It has one annotated transcript and one annotated polypeptide.","inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype","-","-"]
[null,"FBgn0085424","nubbin","nub","The gene nubbin is referred to in FlyBase by the symbol Dmel\\nub (CG34395, FBgn0085424). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12587871..12628143. It has the cytological map location 33F1. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: regulation of transcription from RNA polymerase II promoter. 25 alleles are reported. The phenotypes of these alleles are annotated with 53 unique terms, many of which group under: adult segment; synaptic neuropil subdomain; antennal segment; adult mesothoracic segment; multi-cell-component structure; embryonic neuron; antennal ORN; embryonic nervous system; larval abdominal segment; larval thorax; integumentary specialisation. It has 2 annotated transcripts and 2 annotated polypeptides.","pattern specification process ; GO:0007389 | non-traceable author statement <newline> neuroblast fate determination ; GO:0007400 | non-traceable author statement <newline> ventral cord development ; GO:0007419 | non-traceable author statement <newline> ganglion mother cell fate determination ; GO:0007402 | traceable author statement <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | inferred from sequence or structural similarity with NCBI_gi:4505957","nucleus ; GO:0005634 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with NCBI_gi:4505957","transcription factor activity ; GO:0003700 | non-traceable author statement <newline> RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity with NCBI_gi:4505957 <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR017970 <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000327, InterPro:IPR001356"]
[null,"FBgn0085432","pangolin","pan","The gene pangolin is referred to in FlyBase by the symbol Dmel\\pan (CG34403, FBgn0085432). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:89956..129430. It has the cytological map location 102A3-102A4. There is experimental evidence that it has the molecular function</span>: specific transcriptional repressor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of Wnt receptor signaling pathway; spiracle morphogenesis, open tracheal system; embryonic pattern specification; regulation of hemocyte differentiation; imaginal disc-derived wing morphogenesis; positive regulation of transcription; salivary gland morphogenesis. 44 alleles are reported. The phenotypes of these alleles are annotated with 39 unique terms, many of which group under: organ system; adult segment; late extended germ band embryo; thoracic segment; muscle founder cell; peripheral nervous system; embryonic/larval tracheal system; adult mesothoracic segment; dorsal thoracic disc; spiracle. It has 10 annotated transcripts and 10 annotated polypeptides.","embryonic pattern specification ; GO:0009880 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from sequence or structural similarity with MGD:Tcf7l2; MGI:MGI:1202879 <newline> segment polarity determination ; GO:0007367 | non-traceable author statement <newline> Wnt receptor signaling pathway ; GO:0016055 | traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> mesodermal cell fate determination ; GO:0007500 | traceable author statement <newline> regulation of hemocyte differentiation ; GO:0045610 | inferred from mutant phenotype <newline> spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | non-traceable author statement <newline> regulation of Wnt receptor signaling pathway ; GO:0030111 | inferred from mutant phenotype <newline> negative regulation of Wnt receptor signaling pathway ; GO:0030178 | non-traceable author statement <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> positive regulation of transcription ; GO:0045941 | inferred from mutant phenotype","transcription factor complex ; GO:0005667 | inferred from sequence or structural similarity with MGD:Tcf7l2; MGI:MGI:1202879 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","specific transcriptional repressor activity ; GO:0016566 | inferred from mutant phenotype <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000910"]
[null,"FBgn0085450","Sno oncogene","Snoo","The gene Sno oncogene is referred to in FlyBase by the symbol Dmel\\Snoo (CG34421, FBgn0085450). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:7892316..7984158. It has the cytological map location 28D3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; nucleotide binding. There is experimental evidence that it is involved in the biological process</span>: neuron development; negative regulation of transforming growth factor beta receptor signaling pathway. 33 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: adult segment; adult mesothoracic segment; multi-cell-component structure; thoracic segment; nervous system; egg; organ system; external compound sense organ; chorion; peripheral nervous system. It has 5 annotated transcripts and 5 annotated polypeptides.","negative regulation of transforming growth factor beta receptor signaling pathway ; GO:0030512 | inferred from genetic interaction with babo inferred from genetic interaction with tkv <newline> neuron development ; GO:0048666 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGD:Ski; MGI:MGI:98310","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR014890 <newline> nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR009061"]
[null,"FBgn0086676","spinster","spin","The gene spinster is referred to in FlyBase by the symbol Dmel\\spin (CG8428, FBgn0086676). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12012488..12025743. It has the cytological map location 52E6-52E. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: endosome to lysosome transport; regulation of programmed cell death; endocytosis; locomotion; larval central nervous system remodeling; synaptic vesicle endocytosis; regulation of nurse cell apoptosis; oogenesis; regulation of synaptic growth at neuromuscular junction; regulation of female receptivity. 63 alleles are reported. The phenotypes of these alleles are annotated with: embryonic head; retina; medulla; adult central nervous system; neuromuscular junction; embryonic peripheral nervous system; embryonic central nervous system; egg chamber; endosome; adult brain. It has 5 annotated transcripts and 5 annotated polypeptides.","regulation of synaptic growth at neuromuscular junction ; GO:0008582 | inferred from mutant phenotype <newline> larval central nervous system remodeling ; GO:0035193 | inferred from mutant phenotype <newline> regulation of female receptivity ; GO:0045924 | inferred from mutant phenotype <newline> regulation of nurse cell apoptosis ; GO:0045477 | inferred from mutant phenotype <newline> regulation of programmed cell death ; GO:0043067 | inferred from mutant phenotype <newline> courtship behavior ; GO:0007619 | non-traceable author statement <newline> programmed cell death ; GO:0012501 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> locomotion ; GO:0040011 | inferred from mutant phenotype <newline> synaptic vesicle endocytosis ; GO:0048488 | inferred from mutant phenotype <newline> endosome to lysosome transport ; GO:0008333 | inferred from mutant phenotype <newline> endocytosis ; GO:0006897 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701","plasma membrane ; GO:0005886 | non-traceable author statement","-"]
[null,"FBgn0086902","kismet","kis","The gene kismet is referred to in FlyBase by the symbol Dmel\\kis (CG3696, FBgn0086902). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:210732..250795. It has the cytological map location 21B4-21B5. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent helicase activity. There is experimental evidence that it is involved in the biological process</span>: blastoderm segmentation; segment specification; border follicle cell migration; axon guidance; antimicrobial humoral response. 128 alleles are reported. The phenotypes of these alleles are annotated with: leg; imaginal disc. It has 3 annotated transcripts and 3 annotated polypeptides.","blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype <newline> segment specification ; GO:0007379 | inferred from mutant phenotype <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> chromatin assembly or disassembly ; GO:0006333 | inferred from electronic annotation with InterPro:IPR000953","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with InterPro:IPR000953 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay <newline> chromatin ; GO:0000785 | inferred from electronic annotation with InterPro:IPR000953","ATP-dependent helicase activity ; GO:0008026 | inferred from sequence or structural similarity with InterPro:IPR001410 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330, InterPro:IPR001650 <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000330 <newline> chromatin binding ; GO:0003682 | inferred from electronic annotation with InterPro:IPR000953"]
[null,"FBgn0250823","gilgamesh","gish","The gene gilgamesh is referred to in FlyBase by the symbol Dmel\\gish (CG6963, FBgn0250823). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12098176..12128094. It has the cytological map location 89B9-89B12. Based on sequence similarity, it is predicted to have molecular function</span>: protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: glial cell migration; protein amino acid phosphorylation; Wnt receptor signaling pathway; spermatogenesis. 49 alleles are reported. The phenotypes of these alleles are annotated with: spermatogonium; eye; photoreceptor cell; ommatidium. It has 9 annotated transcripts and 9 annotated polypeptides.","spermatogenesis ; GO:0007283 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> glial cell migration ; GO:0008347 | inferred from mutant phenotype <newline> Wnt receptor signaling pathway ; GO:0016055 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from direct assay","plasma membrane ; GO:0005886 | inferred from direct assay","protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity <newline> protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with UniProtKB:Q62763 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0259176","bunched","bun","The gene bunched is referred to in FlyBase by the symbol Dmel\\bun (CG42281, FBgn0259176). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12456577..12546630. It has the cytological map location 33E5-33E9. Based on sequence similarity, it is predicted to have molecular function</span>: protein homodimerization activity. There is experimental evidence for 13 unique biological process</span> terms, many of which group under: regulation of biological process; anatomical structure development; reproductive process in a multicellular organism; regulation of developmental process; programmed cell death; ovarian follicle cell development; positive regulation of biological process; positive regulation of cell proliferation; regionalization; regulation of anatomical structure size; gland morphogenesis; regulation of apoptosis; negative regulation of Notch signaling pathway. 140 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: external compound sense organ; peripheral nervous system; adult segment; organ system; nervous system; female germline cyst; egg; chorion; thoracic segment; adult mesothoracic segment. It has 8 annotated transcripts and 8 annotated polypeptides.","decapentaplegic receptor signaling pathway ; GO:0008101 | inferred from genetic interaction with dpp <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype <newline> segmentation ; GO:0035282 | inferred from mutant phenotype <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> chorion-containing eggshell formation ; GO:0007304 | inferred from mutant phenotype <newline> negative regulation of cell fate specification ; GO:0009996 | inferred from mutant phenotype <newline> ovarian follicle cell migration ; GO:0007297 | inferred from mutant phenotype <newline> negative regulation of Notch signaling pathway ; GO:0045746 | inferred from mutant phenotype <newline> cell fate determination ; GO:0001709 | non-traceable author statement <newline> dorsal appendage formation ; GO:0046843 | non-traceable author statement <newline> peripheral nervous system development ; GO:0007422 | non-traceable author statement <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> compound eye development ; GO:0048749 | non-traceable author statement <newline> oogenesis ; GO:0048477 | non-traceable author statement <newline> positive regulation of cell proliferation ; GO:0008284 | inferred from mutant phenotype <newline> positive regulation of cell growth ; GO:0030307 | inferred from mutant phenotype <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000580","cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | non-traceable author statement","protein homodimerization activity ; GO:0042803 | inferred from sequence or structural similarity <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR000580"]
[null,"FBgn0259211","grainy head","grh","The gene grainy head is referred to in FlyBase by the symbol Dmel\\grh (CG42311, FBgn0259211). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13690294..13729118. It has the cytological map location 54E10-54F1. There is experimental evidence that it has the molecular function</span>: specific RNA polymerase II transcription factor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; nervous system development; tracheal outgrowth, open tracheal system; regulation of cell proliferation; open tracheal system development; regulation of tube length, open tracheal system; plasma membrane organization; chitin-based embryonic cuticle biosynthetic process. 70 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; embryonic/larval tracheal system; somatic stem cell; cephalopharyngeal skeleton; portion of tissue; cuticle; adult segment; larval abdominal segment; adult mesothoracic segment; developing anatomical structure. It has 7 annotated transcripts and 7 annotated polypeptides.","plasma membrane organization ; GO:0007009 | inferred from mutant phenotype <newline> regulation of cell shape ; GO:0008360 | inferred from mutant phenotype <newline> regulation of tube length, open tracheal system ; GO:0035159 | inferred from mutant phenotype <newline> tracheal outgrowth, open tracheal system ; GO:0007426 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from expression pattern <newline> ganglion mother cell fate determination ; GO:0007402 | traceable author statement <newline> ventral cord development ; GO:0007419 | non-traceable author statement <newline> nervous system development ; GO:0007399 | inferred from mutant phenotype <newline> regulation of cell proliferation ; GO:0042127 | inferred from mutant phenotype <newline> regulation of transcription from RNA polymerase II promoter ; GO:0006357 | non-traceable author statement <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | inferred from mutant phenotype <newline> cellular membrane organization ; GO:0016044 | traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> primary branching, open tracheal system ; GO:0007428 | traceable author statement <newline> regulation of tube architecture, open tracheal system ; GO:0035152 | traceable author statement","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","DNA binding ; GO:0003677 | inferred from direct assay <newline> specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from direct assay <newline> RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement"]
[null,"FBgn0259220","Darkener of apricot","Doa","The gene Darkener of apricot is referred to in FlyBase by the symbol Dmel\\Doa (CG42320, FBgn0259220). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:24713799..24748494. It has the cytological map location 98F1-98F2. There is experimental evidence that it has the molecular function</span>: protein serine/threonine kinase activity; protein kinase activity. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; regulation of biological process; programmed cell death; sensory organ development; biopolymer modification; reproductive developmental process; neuromuscular process; embryonic pattern specification; gland morphogenesis; locomotory behavior; organ morphogenesis; regulation of metabolic process. 56 alleles are reported. The phenotypes of these alleles are annotated with: female genitalia; eye; macrochaeta; female terminalia sensillum; ommatidium; pigment cell. It has 13 annotated transcripts and 13 annotated polypeptides.","central nervous system development ; GO:0007417 | non-traceable author statement <newline> chitin-based embryonic cuticle biosynthetic process ; GO:0008362 | non-traceable author statement <newline> photoreceptor cell maintenance ; GO:0045494 | non-traceable author statement <newline> sex differentiation ; GO:0007548 | inferred from genetic interaction with tra2 AND inferred from genetic interaction with tra AND inferred from mutant phenotype <newline> MAPKKK cascade ; GO:0000165 | inferred from genetic interaction with rl AND inferred from genetic interaction with sev AND inferred from genetic interaction with sina AND inferred from genetic interaction with svp NOT <newline> compound eye photoreceptor development ; GO:0042051 | inferred from expression pattern AND inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> blastoderm segmentation ; GO:0007350 | non-traceable author statement <newline> bristle morphogenesis ; GO:0008407 | non-traceable author statement <newline> compound eye photoreceptor development ; GO:0042051 | non-traceable author statement <newline> nervous system development ; GO:0007399 | non-traceable author statement <newline> autophagic cell death ; GO:0048102 | inferred from expression pattern <newline> salivary gland cell autophagic cell death ; GO:0035071 | inferred from expression pattern <newline> karyosome formation ; GO:0030717 | inferred from mutant phenotype <newline> regulation of alternative nuclear mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | non-traceable author statement <newline> oogenesis ; GO:0048477 | inferred from mutant phenotype <newline> blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | inferred from mutant phenotype <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> protein amino acid autophosphorylation ; GO:0046777 | inferred from direct assay <newline> brain morphogenesis ; GO:0048854 | inferred from mutant phenotype <newline> startle response ; GO:0001964 | inferred from mutant phenotype <newline> locomotion involved in locomotory behavior ; GO:0031987 | inferred from mutant phenotype","nucleus ; GO:0005634 | non-traceable author statement <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> endoplasmic reticulum ; GO:0005783 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred by curator from GO:0000381 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","protein serine/threonine kinase activity ; GO:0004674 | inferred from direct assay <newline> protein kinase activity ; GO:0004672 | inferred from sequence or structural similarity with NCBI_NP:003984 <newline> protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement <newline> protein serine/threonine/tyrosine kinase activity ; GO:0004712 | non-traceable author statement <newline> protein kinase activity ; GO:0004672 | inferred from direct assay <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0259750","abrupt","ab","The gene abrupt is referred to in FlyBase by the symbol Dmel\\ab (CG4807, FBgn0259750). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:11210681..11261080. It has the cytological map location 32E1-32E2. Based on sequence similarity, it is predicted to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: border follicle cell migration; lysosome organization; dendrite morphogenesis; neuron development; muscle organ development; negative regulation of autophagy. 44 alleles are reported. The phenotypes of these alleles are annotated with 53 unique terms, many of which group under: hypodermal muscle of larval abdomen; adult segment; abdominal oblique muscle; adult mesothoracic segment; peripheral nervous system; sensory cluster; organ system; multidendritic neuron; larval abdominal segment 5; multi-cell-component structure. It has 4 annotated transcripts and 4 annotated polypeptides.","axon choice point recognition ; GO:0016198 | traceable author statement <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> negative regulation of autophagy ; GO:0010507 | inferred from mutant phenotype <newline> lysosome organization ; GO:0007040 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with EMBL:AF032676","specific RNA polymerase II transcription factor activity ; GO:0003704 | inferred from sequence or structural similarity with EMBL:AF032676 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000210, InterPro:IPR011333, InterPro:IPR013069 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0259986","nab","nab","The gene nab is referred to in FlyBase by the symbol Dmel\\nab (CG33545, FBgn0259986). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4153618..4160932. It has the cytological map location 64A8. There is experimental evidence that it has the molecular function</span>: transcription cofactor activity. There is experimental evidence that it is involved in the biological process</span>: locomotory behavior; neuron development; wing disc pattern formation. 18 alleles are reported. The phenotypes of these alleles are annotated with: tarsal segment 2; eye; tarsal segment 4; tarsal segment 3; ommatidium; wing hinge; EL neuron; pigment cell. It has 2 annotated transcripts and 2 annotated polypeptides.","locomotory behavior ; GO:0007626 | inferred from mutant phenotype <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | inferred from sequence or structural similarity with UniProtKB:Q62722 <newline> wing disc pattern formation ; GO:0035222 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q62722","transcription cofactor activity ; GO:0003712 | inferred from mutant phenotype inferred from physical interaction with rn inferred from physical interaction with sqz inferred from genetic interaction with rn inferred from genetic interaction with sqz <newline> transcription factor binding ; GO:0008134 | inferred from sequence or structural similarity with EMBL:U47543 <newline> transcription repressor activity ; GO:0016564 | inferred from sequence or structural similarity with UniProtKB:Q62722"]
[null,"FBgn0260003","Dystrophin","Dys","The gene Dystrophin is referred to in FlyBase by the symbol Dmel\\Dys (CG34157, FBgn0260003). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:15286810..15421117. It has the cytological map location 92A5-92A10. There is experimental evidence that it has the molecular function</span>: WW domain binding. There is experimental evidence that it is involved in the biological process</span>: neuromuscular synaptic transmission; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived wing vein specification; regulation of short-term neuronal synaptic plasticity; muscle homeostasis; establishment of cell polarity. 40 alleles are reported. The phenotypes of these alleles are annotated with: posterior crossvein; presynaptic active zone; terminal button. It has 8 annotated transcripts and 8 annotated polypeptides.","imaginal disc-derived wing vein morphogenesis ; GO:0008586 | inferred from mutant phenotype <newline> muscle organ development ; GO:0007517 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> neuromuscular synaptic transmission ; GO:0007274 | inferred from direct assay <newline> regulation of short-term neuronal synaptic plasticity ; GO:0048172 | inferred from direct assay <newline> imaginal disc-derived wing vein specification ; GO:0007474 | inferred from mutant phenotype <newline> establishment of cell polarity ; GO:0030010 | inferred from mutant phenotype <newline> muscle cell homeostasis ; GO:0046716 | inferred from mutant phenotype","cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity <newline> dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from sequence or structural similarity with HGNC_gene:DMD; HGNC:2928; OMIM:300377 AND inferred from sequence or structural similarity with HGNC_gene:DRP2; HGNC:3032; OMIM:300052 AND inferred from sequence or structural similarity with HGNC_gene:UTRN; HGNC:12635; OMIM:128240 <newline> dystrophin-associated glycoprotein complex ; GO:0016010 | non-traceable author statement <newline> dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from sequence or structural similarity <newline> cytoskeleton ; GO:0005856 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> dystrophin-associated glycoprotein complex ; GO:0016010 | inferred from physical interaction with Dg","structural molecule activity ; GO:0005198 | inferred from sequence or structural similarity <newline> structural constituent of muscle ; GO:0008307 | inferred from sequence or structural similarity with HGNC_gene:DMD; HGNC:2928; OMIM:300377 AND inferred from sequence or structural similarity with HGNC_gene:DRP2; HGNC:3032; OMIM:300052 AND inferred from sequence or structural similarity with HGNC_gene:UTRN; HGNC:12635; OMIM:128240 <newline> cytoskeletal protein binding ; GO:0008092 | inferred from sequence or structural similarity <newline> actin binding ; GO:0003779 | inferred from sequence or structural similarity <newline> actin binding ; GO:0003779 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> structural constituent of muscle ; GO:0008307 | inferred from sequence or structural similarity with UniProtKB:P11532 <newline> WW domain binding ; GO:0050699 | inferred from physical interaction with Dg <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000433 <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR011992"]
[null,"FBgn0260635","thread","th","The gene thread is referred to in FlyBase by the symbol Dmel\\th (CG12284, FBgn0260635). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:16031505..16043755. It has the cytological map location 72C1-72D1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: apoptosis; spermatid nucleus differentiation; anti-apoptosis; border follicle cell migration; sensory organ development; cellular process; negative regulation of apoptosis; antennal morphogenesis; positive regulation of protein ubiquitination. 167 alleles are reported. The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: organ system; anatomical structure; embryonic segment; embryonic nervous system; female germline cyst; antennal segment; embryonic head; nervous system; peripheral nervous system; adult segment. It has 3 annotated transcripts and 3 annotated polypeptides.","anti-apoptosis ; GO:0006916 | inferred from direct assay <newline> anti-apoptosis ; GO:0006916 | inferred from genetic interaction with W AND inferred from genetic interaction with rpr <newline> apoptosis ; GO:0006915 | inferred from physical interaction with W AND inferred from physical interaction with rpr <newline> negative regulation of caspase activity ; GO:0043154 | traceable author statement <newline> anti-apoptosis ; GO:0006916 | non-traceable author statement <newline> anti-apoptosis ; GO:0006916 | traceable author statement <newline> apoptosis ; GO:0006915 | traceable author statement <newline> negative regulation of apoptosis ; GO:0043066 | traceable author statement <newline> protein monoubiquitination ; GO:0006513 | traceable author statement <newline> multicellular organismal development ; GO:0007275 | traceable author statement <newline> protein ubiquitination during ubiquitin-dependent protein catabolic process ; GO:0042787 | traceable author statement <newline> apoptosis ; GO:0006915 | non-traceable author statement <newline> spermatid nucleus differentiation ; GO:0007289 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from genetic interaction with Rac1 AND inferred from mutant phenotype <newline> negative regulation of apoptosis ; GO:0043066 | inferred from mutant phenotype AND inferred from sequence or structural similarity <newline> negative regulation of apoptosis ; GO:0043066 | inferred from sequence or structural similarity with UniProtKB:P98170 <newline> germ cell migration ; GO:0008354 | traceable author statement <newline> antennal morphogenesis ; GO:0048800 | inferred from mutant phenotype <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> cellular process ; GO:0009987 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> positive regulation of protein ubiquitination ; GO:0031398 | inferred from direct assay","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001370","ubiquitin-protein ligase activity ; GO:0004842 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from physical interaction with ik2 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841"]
[null,"FBgn0261648","spalt major","salm","The gene spalt major is referred to in FlyBase by the symbol Dmel\\salm (CG6464, FBgn0261648). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:11434311..11445603. It has the cytological map location 32F1-32F2. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity; transcription regulator activity. There is experimental evidence that it is involved in the biological process</span>: oenocyte development; notum cell fate specification; R8 cell differentiation; sensory organ development; compound eye photoreceptor cell differentiation; spiracle morphogenesis, open tracheal system; R7 cell differentiation; open tracheal system development; antennal joint development. 28 alleles are reported. The phenotypes of these alleles are annotated with 52 unique terms, many of which group under: adult segment; adult mesothoracic segment; peripheral nervous system; organ system; nervous system; embryonic/larval tracheal system; embryonic nervous system; antennal segment; appendage segment; embryonic segment. It has one annotated transcript and one annotated polypeptide.","spiracle morphogenesis, open tracheal system ; GO:0035277 | inferred from mutant phenotype <newline> imaginal disc-derived wing vein morphogenesis ; GO:0008586 | traceable author statement <newline> branched duct epithelial cell fate determination, open tracheal system ; GO:0046845 | traceable author statement <newline> negative regulation of transcription ; GO:0016481 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | traceable author statement <newline> sensory organ development ; GO:0007423 | inferred from mutant phenotype <newline> oenocyte development ; GO:0007438 | inferred from mutant phenotype <newline> antennal joint development ; GO:0048098 | inferred from mutant phenotype <newline> R7 cell differentiation ; GO:0045466 | inferred from mutant phenotype <newline> R8 cell differentiation ; GO:0045465 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | non-traceable author statement <newline> epithelial cell migration, open tracheal system ; GO:0007427 | traceable author statement <newline> R8 cell differentiation ; GO:0045465 | non-traceable author statement <newline> segment specification ; GO:0007379 | non-traceable author statement <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype <newline> notum cell fate specification ; GO:0035310 | inferred from mutant phenotype","nucleus ; GO:0005634 | non-traceable author statement <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","specific RNA polymerase II transcription factor activity ; GO:0003704 | non-traceable author statement <newline> transcription regulator activity ; GO:0030528 | non-traceable author statement <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087"]
[null,"FBgn0261873","stardust","sdt","The gene stardust is referred to in FlyBase by the symbol Dmel\\sdt (CG32717, FBgn0261873). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8072582..8133487. It has the cytological map location 7D17-7D22. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: establishment or maintenance of neuroblast polarity; zonula adherens assembly; establishment or maintenance of polarity of embryonic epithelium; establishment or maintenance of epithelial cell apical/basal polarity. 53 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; salivary gland; zonula adherens; amnioserosa; embryonic epidermis; eye photoreceptor cell stalk; trachea; spot adherens junction; macrophage; embryo. It has 7 annotated transcripts and 7 annotated polypeptides.","establishment or maintenance of neuroblast polarity ; GO:0045196 | inferred from mutant phenotype NOT <newline> establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | inferred from expression pattern AND inferred from mutant phenotype AND inferred from physical interaction with crb <newline> establishment or maintenance of polarity of embryonic epithelium ; GO:0016332 | inferred from mutant phenotype <newline> establishment or maintenance of neuroblast polarity ; GO:0045196 | inferred from expression pattern AND inferred from mutant phenotype NOT <newline> zonula adherens assembly ; GO:0045186 | inferred from mutant phenotype <newline> morphogenesis of an epithelium ; GO:0002009 | traceable author statement <newline> zonula adherens assembly ; GO:0045186 | traceable author statement <newline> cell-cell junction assembly ; GO:0007043 | non-traceable author statement <newline> establishment or maintenance of epithelial cell apical/basal polarity ; GO:0045197 | traceable author statement <newline> morphogenesis of an epithelium ; GO:0002009 | non-traceable author statement <newline> establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement <newline> morphogenesis of a polarized epithelium ; GO:0001738 | traceable author statement","adherens junction ; GO:0005912 | inferred from direct assay <newline> apical cortex ; GO:0045179 | inferred from direct assay <newline> apical plasma membrane ; GO:0016324 | inferred from direct assay <newline> apicolateral plasma membrane ; GO:0016327 | inferred from direct assay <newline> membrane ; GO:0016020 | non-traceable author statement <newline> membrane ; GO:0016020 | inferred from sequence or structural similarity with EMBL:AF079366 <newline> plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with EMBL:AF079366 <newline> apical plasma membrane ; GO:0016324 | traceable author statement <newline> cell-cell adherens junction ; GO:0005913 | non-traceable author statement <newline> subapical complex ; GO:0035003 | traceable author statement <newline> apical plasma membrane ; GO:0016324 | non-traceable author statement <newline> septate junction ; GO:0005918 | traceable author statement <newline> cytoplasm ; GO:0005737 | non-traceable author statement","guanylate kinase activity ; GO:0004385 | inferred from sequence or structural similarity with MGD:Mpp5; MGI:MGI:1927339 <newline> guanylate kinase activity ; GO:0004385 | non-traceable author statement <newline> guanylate kinase activity ; GO:0004385 | inferred from sequence or structural similarity with EMBL:AF079366 <newline> guanylate kinase activity ; GO:0004385 | traceable author statement <newline> protein binding ; GO:0005515 | traceable author statement <newline> protein binding ; GO:0005515 | inferred from sequence or structural similarity <newline> protein binding ; GO:0005515 | inferred from physical interaction with par-6"]
[null,"FBgn0259789","vielfaltig","vfl","The gene vielfaltig is referred to in FlyBase by the symbol Dmel\\vfl (CG12701, FBgn0259789). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding. There is experimental evidence that it is involved in the biological process</span>: mitotic cell cycle. 9 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; peripheral nervous system; anatomical structure; adult segment; embryonic nervous system; thoracic segment; integumentary plate; developing anatomical structure; cell part; embryonic neuron. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Zinc finger, C2H2-like; Zinc finger, C2H2-type; Zinc finger, C2H2-type/integrase, DNA-binding; Zinc finger, double-stranded RNA binding. Gene sequence location is X:19670020..19676961.","mitotic cell cycle ; GO:0000278 | inferred from mutant phenotype","chromatin ; GO:0000785 | colocalizes_with inferred from direct assay <newline> nucleoplasm ; GO:0005654 | inferred from direct assay","sequence-specific DNA binding ; GO:0043565 | inferred from direct assay <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0261570","-","CG42684","This gene is referred to in FlyBase by the symbol Dmel\\CG42684 (FBgn0261570). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: Ras GTPase activator activity. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior. 28 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: C2 calcium-dependent membrane targeting; C2 calcium/lipid-binding domain, CaLB; Pleckstrin homology domain; Protein of unknown function DUF3498; Ras GTPase-activating protein; Ras GTPase-activating protein, conserved site; Rho GTPase activation protein. Gene sequence location is X:17604819..17645718.","Ras protein signal transduction ; GO:0007265 | inferred from sequence or structural similarity with UniProtKB:Q9UJF2 <newline> negative regulation of Ras protein signal transduction ; GO:0046580 | inferred from sequence or structural similarity with UniProtKB:Q9UAI0 <newline> inter-male aggressive behavior ; GO:0002121 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from sequence or structural similarity with UniProtKB:Q9UAI0","Ras GTPase activator activity ; GO:0005099 | inferred from sequence or structural similarity with UniProtKB:Q9UJF2 <newline> Ras GTPase activator activity ; GO:0005099 | inferred from sequence or structural similarity with UniProtKB:Q9UAI0"]
[null,"FBgn0003559","suppressor of forked","su(f)","The gene suppressor of forked is referred to in FlyBase by the symbol Dmel\\su(f) (CG17170, FBgn0003559). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mRNA cleavage. 50 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; adult segment; peripheral nervous system; nervous system; thoracic segment; adult mesothoracic segment; integumentary plate; female germline cyst; external compound sense organ; prothoracic leg; adult. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: RNA-processing protein, HAT helix; Suppressor of forked. Gene sequence location is XHet:69195..80010.","mRNA cleavage ; GO:0006379 | inferred from sequence or structural similarity with NCBI_NP:001317 <newline> mRNA cleavage ; GO:0006379 | inferred from sequence or structural similarity <newline> mRNA cleavage ; GO:0006379 | inferred from sequence or structural similarity with NCBI_gi:4557495 <newline> RNA metabolic process ; GO:0016070 | non-traceable author statement","mRNA cleavage stimulating factor complex ; GO:0005848 | inferred from sequence or structural similarity with NCBI_NP:001317 <newline> mRNA cleavage stimulating factor complex ; GO:0005848 | inferred from sequence or structural similarity <newline> mRNA cleavage and polyadenylation specificity factor complex ; GO:0005847 | inferred from sequence or structural similarity with NCBI_gi:4557495 <newline> nucleus ; GO:0005634 | non-traceable author statement","-"]
[null,"FBgn0016792","dalmatian","dmt","The gene dalmatian is referred to in FlyBase by the symbol Dmel\\dmt (CG8374, FBgn0016792). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: mitotic sister chromatid cohesion; nervous system development; mitotic spindle organization. 11 alleles are reported. The phenotype of these alleles is annotated with: peripheral nervous system. It has one annotated transcript and one annotated polypeptide. Protein features are: HMG-I/HMG-Y, DNA-binding, conserved site. Gene sequence location is 3R:5536862..5540397.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype <newline> nervous system development ; GO:0007399 | inferred from mutant phenotype <newline> mitotic sister chromatid cohesion ; GO:0007064 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR000637","chromatin ; GO:0000785 | colocalizes_with inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from sequence model","-"]
[null,"FBgn0035989","-","CG3967","This gene is referred to in FlyBase by the symbol Dmel\\CG3967 (FBgn0035989). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: behavioral response to ethanol. 11 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Acyl-CoA N-acyltransferase; Touch receptor neuron protein Mec-17. Gene sequence location is 3L:9406696..9419777.","behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
[null,"FBgn0261599","Ribosomal protein S29","RpS29","The gene Ribosomal protein S29 is referred to in FlyBase by the symbol Dmel\\RpS29 (CG8495, FBgn0261599). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of ribosome. There is experimental evidence that it is involved in the biological process</span>: neuron development. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Ribosomal protein S14; Ribosomal protein S14, conserved site. Gene sequence location is 3R:5603767..5604800.","translation ; GO:0006412 | inferred from sequence or structural similarity with NCBI_gi:4506717 <newline> neuron development ; GO:0048666 | inferred from mutant phenotype","cytosolic small ribosomal subunit ; GO:0022627 | inferred from sequence or structural similarity with NCBI_gi:4506717","structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with NCBI_gi:4506717"]
[null,"FBgn0029174","FK506-binding protein FKBP59","FKBP59","The gene FK506-binding protein FKBP59 is referred to in FlyBase by the symbol Dmel\\FKBP59 (CG4535, FBgn0029174). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: regulation of calcium ion transport; detection of light stimulus involved in visual perception. 6 alleles are reported. The phenotypes of these alleles are annotated with: plasmatocyte; fascicle; embryonic peripheral nervous system; crystal cell. It has one annotated transcript and one annotated polypeptide. Protein features are: Elongated TPR repeat-containing domain; Peptidyl-prolyl cis-trans isomerase, FKBP-type; Tetratricopeptide TPR-1; Tetratricopeptide repeat; Tetratricopeptide repeat-containing; Tetratricopeptide-like helical. Gene sequence location is 2L:9888034..9890119.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> regulation of calcium ion transport ; GO:0051924 | inferred from direct assay <newline> detection of light stimulus involved in visual perception ; GO:0050908 | inferred from physical interaction with inaD inferred from physical interaction with trpl <newline> protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR001179","inaD signaling complex ; GO:0016027 | inferred from physical interaction with inaD","FK506 binding ; GO:0005528 | inferred from sequence or structural similarity <newline> peptidyl-prolyl cis-trans isomerase activity ; GO:0003755 | inferred from sequence or structural similarity <newline> FK506 binding ; GO:0005528 | inferred from sequence or structural similarity with HGNC_gene:FKBP4; HGNC:3720 <newline> protein binding ; GO:0005515 | inferred from physical interaction with inaD inferred from physical interaction with trpl"]
[null,"FBgn0000667","alpha actinin","Actn","The gene Î± actinin is referred to in FlyBase by the symbol Dmel\\Actn (CG4376, FBgn0000667). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: calcium ion binding; actin filament binding; actin binding. There is experimental evidence that it is involved in the biological process</span>: flight behavior; sarcomere organization; actin cytoskeleton reorganization. 41 alleles are reported. The phenotypes of these alleles are annotated with: Z disc; eye; myofibril; ovariole; somatic muscle; sarcomere; third instar larva; indirect flight muscle; muscle cell. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Actinin-type, actin-binding, conserved site; Calcium-binding EF-hand; Calponin homology domain; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand, Ca insensitive; EF-hand-like domain; Spectrin repeat; Spectrin/alpha-actinin. Gene sequence location is X:1919149..1936344.","actin filament bundle assembly ; GO:0051017 | inferred from sequence or structural similarity with EMBL:AF093775 <newline> cytoskeletal anchoring at plasma membrane ; GO:0007016 | inferred from sequence or structural similarity <newline> flight behavior ; GO:0007629 | inferred from mutant phenotype <newline> actin filament bundle assembly ; GO:0051017 | non-traceable author statement <newline> actin cytoskeleton reorganization ; GO:0031532 | inferred from mutant phenotype <newline> sarcomere organization ; GO:0045214 | inferred from mutant phenotype","focal adhesion ; GO:0005925 | inferred from sequence or structural similarity <newline> Z disc ; GO:0030018 | inferred from direct assay","actin filament binding ; GO:0051015 | inferred from sequence or structural similarity with EMBL:AF093775 <newline> calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with EMBL:AF093775 <newline> actin binding ; GO:0003779 | inferred from sequence or structural similarity"]
[null,"FBgn0031057","Ubiquilin","Ubqn","The gene Ubiquilin is referred to in FlyBase by the symbol Dmel\\Ubqn (CG14224, FBgn0031057). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: amyloid precursor protein metabolic process. 8 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; organ system; thoracic segment; adult; external compound sense organ; pigment cell; peripheral nervous system; region of integument; neuropil; histaminergic neuron. It has one annotated transcript and one annotated polypeptide. Protein features are: Heat shock chaperonin-binding; UBA-like; Ubiquilin; Ubiquitin; Ubiquitin supergroup; Ubiquitin-associated/translation elongation factor EF1B, N-terminal; Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote. Gene sequence location is X:19577781..19581273.","amyloid precursor protein metabolic process ; GO:0042982 | inferred from mutant phenotype","-","-"]
[null,"FBgn0022764","Sin3A","Sin3A","The gene Sin3A is referred to in FlyBase by the symbol Dmel\\Sin3A (CG8815, FBgn0022764). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: transcription repressor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of transcription; dendrite morphogenesis; neuron development; regulation of mitotic cell cycle; muscle organ development; negative regulation of transcription, DNA-dependent. 59 alleles are reported. The phenotypes of these alleles are annotated with: embryonic heart; mitochondrion; crystal cell. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Histone deacetylase interacting; Paired amphipathic helix. Gene sequence location is 2R:8462745..8480397.","peripheral nervous system development ; GO:0007422 | traceable author statement <newline> negative regulation of transcription ; GO:0016481 | inferred from expression pattern <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | inferred from mutant phenotype <newline> regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with SGD_LOCUS:SIN3; SGD:S0005364 <newline> negative regulation of transcription, DNA-dependent ; GO:0045892 | traceable author statement <newline> muscle organ development ; GO:0007517 | inferred from mutant phenotype <newline> dendrite morphogenesis ; GO:0048813 | inferred from mutant phenotype <newline> neuron development ; GO:0048666 | inferred from mutant phenotype <newline> regulation of mitotic cell cycle ; GO:0007346 | inferred from mutant phenotype <newline> negative regulation of transcription ; GO:0016481 | inferred from direct assay","nucleus ; GO:0005634 | non-traceable author statement <newline> chromatin ; GO:0000785 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from direct assay <newline> Sin3 complex ; GO:0016580 | non-traceable author statement <newline> euchromatin ; GO:0000791 | traceable author statement <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with SGD_LOCUS:SIN3; SGD:S0005364 <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> polytene chromosome ; GO:0005700 | inferred from direct assay","RNA polymerase II transcription factor activity ; GO:0003702 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | inferred from mutant phenotype <newline> sequence-specific DNA binding transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with SGD_LOCUS:SIN3; SGD:S0005364 <newline> transcription cofactor activity ; GO:0003712 | non-traceable author statement <newline> transcription repressor activity ; GO:0016564 | inferred from direct assay"]
[null,"FBgn0000479","dunce","dnc","The gene dunce is referred to in FlyBase by the symbol Dmel\\dnc (CG32498, FBgn0000479). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: 3',5'-cyclic-AMP phosphodiesterase activity. There is experimental evidence that it is involved in the biological process</span>: synaptic transmission; conditioned taste aversion; short-term memory; learning; axon extension. 72 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; nervous system; anatomical structure; embryonic neuron; synapse; peripheral nervous system; embryonic nervous system; female germline cyst; egg; synaptic neuropil subdomain; postsynaptic membrane; adult brain. It has 12 annotated transcripts and 12 annotated polypeptides. Protein features are: 3'5'-cyclic nucleotide phosphodiesterase; 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain; 3'5'-cyclic nucleotide phosphodiesterase, conserved site; Metal-dependent phosphohydrolase, HD domain; Twin-arginine translocation pathway, signal sequence. Gene sequence location is X:3070475..3233360.","cyclic nucleotide metabolic process ; GO:0009187 | non-traceable author statement <newline> cAMP-mediated signaling ; GO:0019933 | non-traceable author statement <newline> courtship behavior ; GO:0007619 | traceable author statement <newline> learning ; GO:0007612 | non-traceable author statement <newline> olfactory learning ; GO:0008355 | traceable author statement <newline> behavioral response to ethanol ; GO:0048149 | non-traceable author statement <newline> learning or memory ; GO:0007611 | non-traceable author statement <newline> locomotor rhythm ; GO:0045475 | non-traceable author statement <newline> reproduction ; GO:0000003 | non-traceable author statement <newline> synaptic transmission ; GO:0007268 | inferred from mutant phenotype <newline> circadian rhythm ; GO:0007623 | traceable author statement <newline> associative learning ; GO:0008306 | traceable author statement <newline> mating behavior ; GO:0007617 | traceable author statement <newline> memory ; GO:0007613 | traceable author statement <newline> nonassociative learning ; GO:0046958 | traceable author statement <newline> oogenesis ; GO:0048477 | traceable author statement <newline> axon extension ; GO:0048675 | inferred from mutant phenotype <newline> short-term memory ; GO:0007614 | inferred from mutant phenotype <newline> conditioned taste aversion ; GO:0001661 | inferred from mutant phenotype <newline> learning ; GO:0007612 | inferred from mutant phenotype <newline> signal transduction ; GO:0007165 | inferred from electronic annotation with InterPro:IPR002073","-","3',5'-cyclic-AMP phosphodiesterase activity ; GO:0004115 | inferred from sequence or structural similarity with EMBL:U50157 <newline> 3',5'-cyclic-nucleotide phosphodiesterase activity ; GO:0004114 | non-traceable author statement"]
[null,"FBgn0011656","Myocyte enhancer factor 2","Mef2","The gene Myocyte enhancer factor 2 is referred to in FlyBase by the symbol Dmel\\Mef2 (CG1429, FBgn0011656). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: myoblast fusion; muscle fiber development; skeletal muscle tissue development; regulation of gene expression; anterior midgut development; locomotor rhythm; mesoderm development. 63 alleles are reported. The phenotypes of these alleles are annotated with 45 unique terms, many of which group under: organ system; adult segment; abdominal transverse muscle; adult mesothoracic segment; lateral transverse muscle; peripheral nervous system; embryonic/larval hypodermal muscle; primordium; egg; indirect flight muscle. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Holliday junction regulator protein family C-terminal repeat; Transcription factor, MADS-box. Gene sequence location is 2R:5801001..5846313.","mesoderm development ; GO:0007498 | inferred from mutant phenotype <newline> skeletal muscle tissue development ; GO:0007519 | inferred from mutant phenotype <newline> transcription from RNA polymerase II promoter ; GO:0006366 | inferred from sequence or structural similarity with UniProtKB:Q02078 <newline> ovarian follicle cell development ; GO:0030707 | traceable author statement <newline> mesoderm development ; GO:0007498 | inferred from expression pattern <newline> regulation of striated muscle tissue development ; GO:0016202 | traceable author statement <newline> regulation of transcription, DNA-dependent ; GO:0006355 | non-traceable author statement <newline> heart development ; GO:0007507 | traceable author statement <newline> anterior midgut development ; GO:0007496 | inferred from mutant phenotype <newline> muscle fiber development ; GO:0048747 | inferred from mutant phenotype <newline> myoblast fusion ; GO:0007520 | inferred from mutant phenotype <newline> regulation of gene expression ; GO:0010468 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR002100 <newline> locomotor rhythm ; GO:0045475 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:Q02078 <newline> nucleus ; GO:0005634 | non-traceable author statement","RNA polymerase II transcription factor activity ; GO:0003702 | inferred from sequence or structural similarity with UniProtKB:Q02078 <newline> sequence-specific DNA binding transcription factor activity ; GO:0003700 | non-traceable author statement <newline> sequence-specific DNA binding ; GO:0043565 | inferred from electronic annotation with InterPro:IPR002100 <newline> sequence-specific DNA binding transcription factor activity ; GO:0003700 | inferred from electronic annotation with InterPro:IPR002100"]
[null,"FBgn0010575","scribbler","sbb","The gene scribbler is referred to in FlyBase by the symbol Dmel\\sbb (CG5580, FBgn0010575). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: transcription corepressor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of gene-specific transcription from RNA polymerase II promoter; axon guidance; wing disc dorsal/ventral pattern formation; imaginal disc-derived wing morphogenesis; axon target recognition; regulation of imaginal disc growth; negative regulation of smoothened signaling pathway; larval locomotory behavior. 93 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: peripheral nervous system; adult segment; organ system; nervous system; integumentary plate; thoracic segment; multi-cell-component structure; adult mesothoracic segment; synaptic neuropil subdomain; dorsal thoracic disc. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Zinc finger, C2H2-like; Zinc finger, C2H2-type. Gene sequence location is 2R:14166570..14244766.","axon target recognition ; GO:0007412 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | inferred from mutant phenotype <newline> larval locomotory behavior ; GO:0008345 | inferred from mutant phenotype <newline> axon guidance ; GO:0007411 | non-traceable author statement <newline> negative regulation of transcription from RNA polymerase II promoter ; GO:0000122 | non-traceable author statement <newline> photoreceptor cell development ; GO:0042461 | non-traceable author statement <newline> larval locomotory behavior ; GO:0008345 | traceable author statement <newline> regulation of imaginal disc growth ; GO:0045570 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> negative regulation of gene-specific transcription from RNA polymerase II promoter ; GO:0010553 | inferred from mutant phenotype <newline> wing disc dorsal/ventral pattern formation ; GO:0048190 | inferred from genetic interaction with Bx, ap <newline> negative regulation of smoothened signaling pathway ; GO:0045879 | inferred from mutant phenotype","nucleus ; GO:0005634 | inferred from direct assay <newline> nucleus ; GO:0005634 | non-traceable author statement","sequence-specific DNA binding transcription factor activity ; GO:0003700 | non-traceable author statement <newline> transcription corepressor activity ; GO:0003714 | inferred from direct assay <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
[null,"FBgn0086782","amnesiac","amn","The gene amnesiac is referred to in FlyBase by the symbol Dmel\\amn (CG11937, FBgn0086782).The gene has a gene model, but the supporting evidence is inconclusive. It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: neuropeptide hormone activity. There is experimental evidence that it is involved in the biological process</span>: olfactory learning; perineurial glial growth; learning or memory; memory; response to heat; GO:0072375; antimicrobial humoral response; behavioral response to ethanol; behavioral response to pain. 85 alleles are reported. The phenotypes of these alleles are annotated with: mushroom body calyx; eye; central nervous system; surface associated glial cell; embryonic/larval heart; bouton; Kenyon cell; intersegmental nerve; wing vein. It has one annotated transcript and one annotated polypeptide. Gene sequence location is X:19780141..19784093.","learning or memory ; GO:0007611 | inferred from mutant phenotype <newline> memory ; GO:0007613 | traceable author statement <newline> neuropeptide signaling pathway ; GO:0007218 | traceable author statement <newline> learning or memory ; GO:0007611 | non-traceable author statement <newline> cAMP-mediated signaling ; GO:0019933 | non-traceable author statement <newline> courtship behavior ; GO:0007619 | traceable author statement <newline> learning ; GO:0007612 | traceable author statement NOT <newline> olfactory learning ; GO:0008355 | traceable author statement <newline> behavioral response to ethanol ; GO:0048149 | non-traceable author statement <newline> regulation of heart contraction ; GO:0008016 | non-traceable author statement <newline> behavioral response to ethanol ; GO:0048149 | inferred from mutant phenotype <newline> anesthesia-resistant memory ; GO:0007615 | traceable author statement <newline> cAMP biosynthetic process ; GO:0006171 | traceable author statement <newline> long-term memory ; GO:0007616 | traceable author statement <newline> antimicrobial humoral response ; GO:0019730 | inferred from mutant phenotype <newline> male courtship behavior ; GO:0008049 | traceable author statement <newline> memory ; GO:0007613 | inferred from mutant phenotype <newline> activation of adenylate cyclase activity ; GO:0007190 | traceable author statement <newline> cAMP-mediated signaling ; GO:0019933 | traceable author statement <newline> perineurial glial growth ; GO:0042066 | inferred from mutant phenotype <newline> olfactory learning ; GO:0008355 | inferred from direct assay <newline> response to heat ; GO:0009408 | inferred from mutant phenotype <newline> behavioral response to pain ; GO:0048266 | inferred from mutant phenotype <newline> medium-term memory ; GO:0072375 | inferred from mutant phenotype","-","neuropeptide hormone activity ; GO:0005184 | inferred from sequence or structural similarity <newline> neuropeptide hormone activity ; GO:0005184 | traceable author statement <newline> neuropeptide hormone activity ; GO:0005184 | non-traceable author statement <newline> G-protein-coupled receptor binding ; GO:0001664 | non-traceable author statement"]
[null,"FBgn0003741","transformer","tra","The gene transformer is referred to in FlyBase by the symbol Dmel\\tra (CG16724, FBgn0003741). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: male courtship behavior, veined wing generated song production; inter-male aggressive behavior; male courtship behavior, veined wing extension; male courtship behavior. 59 alleles are reported. The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; cytoplasmic part; adult segment; larval abdominal segment; nervous system; imaginal precursor; hub cell; spermatocyte; spermatozoon; female germline cyst; primordium; female genitalia. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Fruit fly transformer. Gene sequence location is 3L:16583032..16584413.","female somatic sex determination ; GO:0019101 | traceable author statement <newline> nuclear mRNA splicing, via spliceosome ; GO:0000398 | non-traceable author statement <newline> sex determination, primary response to X:A ratio ; GO:0007541 | non-traceable author statement <newline> somatic sex determination ; GO:0018993 | non-traceable author statement <newline> spliceosome assembly ; GO:0000245 | non-traceable author statement <newline> sex determination ; GO:0007530 | non-traceable author statement <newline> RNA splicing ; GO:0008380 | traceable author statement <newline> sex differentiation ; GO:0007548 | traceable author statement <newline> female sex determination ; GO:0030237 | non-traceable author statement <newline> nuclear mRNA splicing, via spliceosome ; GO:0000398 | traceable author statement <newline> sex determination ; GO:0007530 | traceable author statement <newline> male courtship behavior, veined wing generated song production ; GO:0045433 | inferred from mutant phenotype <newline> male courtship behavior, veined wing extension ; GO:0048065 | inferred from mutant phenotype <newline> male courtship behavior ; GO:0008049 | inferred from mutant phenotype <newline> negative regulation of translation ; GO:0017148 | non-traceable author statement <newline> male courtship behavior ; GO:0008049 | inferred from direct assay <newline> inter-male aggressive behavior ; GO:0002121 | inferred from direct assay <newline> female sex differentiation ; GO:0046660 | inferred from electronic annotation with InterPro:IPR010519 <newline> mRNA processing ; GO:0006397 | inferred from electronic annotation with InterPro:IPR010519","spliceosomal complex ; GO:0005681 | non-traceable author statement <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR010519","-"]
[null,"FBgn0027054","COP9 complex homolog subunit 4","CSN4","The gene COP9 complex homolog subunit 4 is referred to in FlyBase by the symbol Dmel\\CSN4 (CG8725, FBgn0027054). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: protein binding; promoter binding; NEDD8 activating enzyme activity. There is experimental evidence that it is involved in the biological process</span>: protein deneddylation; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; compound eye photoreceptor cell differentiation; protein stabilization. 8 alleles are reported. The phenotypes of these alleles are annotated with: cephalopharyngeal skeleton; photoreceptor cell. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Proteasome component (PCI) domain; Tetratricopeptide-like helical; Winged helix-turn-helix transcription repressor DNA-binding. Gene sequence location is 2R:3859680..3861604.","protein deneddylation ; GO:0000338 | inferred from mutant phenotype <newline> compound eye photoreceptor cell differentiation ; GO:0001751 | inferred from mutant phenotype <newline> negative regulation of proteasomal ubiquitin-dependent protein catabolic process ; GO:0032435 | inferred from mutant phenotype <newline> protein stabilization ; GO:0050821 | inferred from mutant phenotype","signalosome ; GO:0008180 | inferred from sequence or structural similarity <newline> signalosome ; GO:0008180 | inferred from mutant phenotype <newline> signalosome ; GO:0008180 | non-traceable author statement <newline> signalosome ; GO:0008180 | traceable author statement <newline> signalosome ; GO:0008180 | inferred from physical interaction with CSN7","NEDD8 activating enzyme activity ; GO:0019781 | inferred from mutant phenotype <newline> protein binding ; GO:0005515 | inferred from physical interaction with CSN7 <newline> promoter binding ; GO:0010843 | inferred from direct assay"]
[null,"FBgn0038167","lkb1","lkb1","The gene lkb1 is referred to in FlyBase by the symbol Dmel\\lkb1 (CG9374, FBgn0038167). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function</span>: protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: border follicle cell delamination; dorsal closure; regulation of JNK cascade; oocyte microtubule cytoskeleton organization; pole plasm oskar mRNA localization; mitotic spindle organization; asymmetric neuroblast division; positive regulation of apoptosis. 23 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; organelle; adult segment; thoracic segment; spindle; anatomical structure; peripheral nervous system; intracellular organelle part; spindle microtubule; adult. It has 9 annotated transcripts and 9 annotated polypeptides. Protein features are: Calcium/calmodulin-dependent protein kinase-like; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase STK; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain. Gene sequence location is 3R:9502271..9505152.","protein phosphorylation ; GO:0006468 | non-traceable author statement <newline> oocyte microtubule cytoskeleton organization ; GO:0016325 | inferred from mutant phenotype <newline> establishment or maintenance of cell polarity ; GO:0007163 | non-traceable author statement <newline> pole plasm oskar mRNA localization ; GO:0045451 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype <newline> asymmetric neuroblast division ; GO:0055059 | inferred from mutant phenotype <newline> border follicle cell delamination ; GO:0030709 | inferred from mutant phenotype <newline> positive regulation of apoptosis ; GO:0043065 | inferred from direct assay <newline> dorsal closure ; GO:0007391 | inferred from mutant phenotype <newline> regulation of JNK cascade ; GO:0046328 | inferred from direct assay <newline> protein phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR008271, InterPro:IPR015735, InterPro:IPR017441, InterPro:IPR017442","nucleus ; GO:0005634 | inferred from direct assay <newline> cytoplasm ; GO:0005737 | inferred from direct assay","protein kinase activity ; GO:0004672 | non-traceable author statement <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from electronic annotation with InterPro:IPR002290, InterPro:IPR008271, InterPro:IPR015735 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR015735, InterPro:IPR017441, InterPro:IPR017442"]
[null,"FBgn0004603","Src oncogene at 42A","Src42A","The gene Src oncogene at 42A is referred to in FlyBase by the symbol Dmel\\Src42A (CG7873, FBgn0004603). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: protein tyrosine kinase activity. There is experimental evidence for 15 unique biological process</span> terms, many of which group under: anatomical structure development; macromolecule modification; localization; protein modification process; organ morphogenesis; post-embryonic organ morphogenesis; organ development; gland morphogenesis; biological regulation; cellular macromolecule metabolic process; signaling pathway; catabolic process; actin filament-based process. 55 alleles are reported. The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: organ system; adult segment; nervous system; cuticle; adult mesothoracic segment; external compound sense organ; peripheral nervous system; embryonic/larval tracheal system; embryonic nervous system; taenidial fold; female germline cyst; rhabdomere; egg; embryonic segment; cephalopharyngeal skeleton; late extended germ band embryo. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; SH2 motif; Serine-threonine/tyrosine-protein kinase; Src homology-3 domain; Tyrosine-protein kinase; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, non-receptor FRK. Gene sequence location is 2R:1868785..1900039.","cell communication ; GO:0007154 | inferred from direct assay <newline> negative regulation of epidermal growth factor receptor signaling pathway ; GO:0042059 | inferred from genetic interaction with Ras85D <newline> transmembrane receptor protein tyrosine kinase signaling pathway ; GO:0007169 | inferred from genetic interaction with phl <newline> dorsal closure ; GO:0007391 | inferred from genetic interaction with Src64B AND inferred from genetic interaction with bsk AND inferred from genetic interaction with hep AND inferred from mutant phenotype <newline> protein phosphorylation ; GO:0006468 | non-traceable author statement <newline> peptidyl-tyrosine phosphorylation ; GO:0018108 | inferred from mutant phenotype <newline> protein phosphorylation ; GO:0006468 | inferred from direct assay AND inferred from mutant phenotype <newline> dorsal closure, spreading of leading edge cells ; GO:0007395 | inferred from mutant phenotype <newline> imaginal disc fusion, thorax closure ; GO:0046529 | inferred from mutant phenotype <newline> JNK cascade ; GO:0007254 | traceable author statement <newline> dorsal closure ; GO:0007391 | traceable author statement <newline> compound eye development ; GO:0048749 | inferred from mutant phenotype <newline> dorsal closure ; GO:0007391 | inferred from genetic interaction with Fps85D inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> imaginal disc-derived wing morphogenesis ; GO:0007476 | inferred from mutant phenotype <newline> salivary gland morphogenesis ; GO:0007435 | inferred from mutant phenotype <newline> actin filament bundle assembly ; GO:0051017 | inferred from mutant phenotype <newline> apoptotic cell clearance ; GO:0043277 | inferred from mutant phenotype <newline> tricarboxylic acid cycle ; GO:0006099 | inferred from direct assay","adherens junction ; GO:0005912 | inferred from direct assay <newline> intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR020702","non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from sequence or structural similarity <newline> protein tyrosine kinase activity ; GO:0004713 | inferred from sequence or structural similarity <newline> protein tyrosine kinase activity ; GO:0004713 | non-traceable author statement <newline> protein tyrosine kinase activity ; GO:0004713 | inferred from direct assay <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441, InterPro:IPR020702 <newline> non-membrane spanning protein tyrosine kinase activity ; GO:0004715 | inferred from electronic annotation with InterPro:IPR020702"]
[null,"FBgn0001942","Eukaryotic initiation factor 4a","eIF-4a","The gene Eukaryotic initiation factor 4a is referred to in FlyBase by the symbol Dmel\\eIF-4a (CG9075, FBgn0001942). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: translation initiation factor activity; RNA helicase activity. There is experimental evidence that it is involved in the biological process</span>: germ-line stem cell maintenance; mitotic spindle elongation; response to DNA damage stimulus; mitosis; mitotic spindle organization; dorsal/ventral axis specification; oogenesis; female germ-line stem cell division; regulation of alternative nuclear mRNA splicing, via spliceosome. 66 alleles are reported. The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: anatomical structure; developing anatomical structure; organ system; cuticle; peripheral nervous system; nervous system; parasegment 9; dorsal thoracic disc; multi-cell-component structure; parasegment 14; parasegment 2; cephalopharyngeal skeleton; external compound sense organ; late extended germ band embryo. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: DEAD-like helicase, N-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Helicase, superfamily 1/2, ATP-binding domain; RNA helicase, ATP-dependent, DEAD-box, conserved site; RNA helicase, DEAD-box type, Q motif. Gene sequence location is 2L:5981759..5985572.","dorsal/ventral axis specification ; GO:0009950 | inferred from mutant phenotype <newline> translational initiation ; GO:0006413 | inferred from sequence or structural similarity with SGD_LOCUS:TIF1; SGD:S0001767 <newline> translational initiation ; GO:0006413 | non-traceable author statement <newline> imaginal disc growth ; GO:0007446 | traceable author statement <newline> instar larval development ; GO:0002168 | traceable author statement <newline> translational initiation ; GO:0006413 | inferred from sequence or structural similarity <newline> DNA unwinding involved in replication ; GO:0006268 | non-traceable author statement <newline> regulation of alternative nuclear mRNA splicing, via spliceosome ; GO:0000381 | inferred from mutant phenotype <newline> mitotic spindle elongation ; GO:0000022 | inferred from mutant phenotype <newline> mitotic spindle organization ; GO:0007052 | inferred from mutant phenotype <newline> oogenesis ; GO:0048477 | inferred from genetic interaction with bam <newline> female germ-line stem cell division ; GO:0048132 | inferred from genetic interaction with bam inferred from mutant phenotype <newline> germ-line stem cell maintenance ; GO:0030718 | inferred from mutant phenotype <newline> response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype <newline> mitosis ; GO:0007067 | inferred from mutant phenotype","eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity with SGD_LOCUS:TIF1; SGD:S0001767 <newline> cytosol ; GO:0005829 | non-traceable author statement <newline> cytosol ; GO:0005829 | inferred from sequence or structural similarity <newline> eukaryotic translation initiation factor 4F complex ; GO:0016281 | inferred from sequence or structural similarity <newline> nucleus ; GO:0005634 | inferred by curator from GO:0000381 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity <newline> translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity with SGD_LOCUS:TIF1; SGD:S0001767 <newline> translation initiation factor activity ; GO:0003743 | non-traceable author statement <newline> RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity with SGD_LOCUS:TIF2; SGD:S0003674 <newline> translation initiation factor activity ; GO:0003743 | inferred from sequence or structural similarity <newline> RNA cap binding ; GO:0000339 | non-traceable author statement <newline> mRNA binding ; GO:0003729 | non-traceable author statement <newline> single-stranded DNA-dependent ATP-dependent DNA helicase activity ; GO:0017116 | non-traceable author statement <newline> ATP-dependent helicase activity ; GO:0008026 | inferred from electronic annotation with InterPro:IPR000629, InterPro:IPR011545 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000629, InterPro:IPR001650, InterPro:IPR011545"]
[null,"FBgn0262114","Ran-binding protein M","RanBPM","The gene Ran-binding protein M is referred to in FlyBase by the symbol Dmel\\RanBPM (CG42236, FBgn0262114). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: Ran GTPase binding. There is experimental evidence that it is involved in the biological process</span>: larval feeding behavior; ovarian follicle cell-cell adhesion; germ-line stem-cell niche homeostasis; cytoskeleton organization; dorsal appendage formation. 14 alleles are reported. The phenotypes of these alleles are annotated with: terminal filament; ovary; germline stem cell; germarium cap cell; egg chamber. It has 4 annotated transcripts and 4 annotated polypeptides. Gene sequence location is 2R:6317217..6324086.","germ-line stem-cell niche homeostasis ; GO:0060250 | inferred from mutant phenotype <newline> cytoskeleton organization ; GO:0007010 | inferred from direct assay <newline> dorsal appendage formation ; GO:0046843 | inferred from mutant phenotype <newline> ovarian follicle cell-cell adhesion ; GO:0007299 | inferred from mutant phenotype <newline> larval feeding behavior ; GO:0030536 | inferred from mutant phenotype","cytoplasm ; GO:0005737 | inferred from direct assay","Ran GTPase binding ; GO:0008536 | inferred from sequence or structural similarity with HGNC_gene:RANBP9; HGNC:13727"]
[null,"FBgn0043903","domeless","dome","The gene domeless is referred to in FlyBase by the symbol Dmel\\dome (CG14226, FBgn0043903). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: transmembrane receptor activity. There is experimental evidence that it is involved in the biological process</span>: blastoderm segmentation; morphogenesis of an epithelium; hindgut morphogenesis; border follicle cell migration; JAK-STAT cascade; open tracheal system development; compound eye morphogenesis. 45 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; anatomical structure; integumentary specialisation; spiracle; multi-tissue structure; region of integument; ovariole; portion of tissue; embryonic hindgut; non-connected developing functional system; external compound sense organ; adult segment. It has one annotated transcript and one annotated polypeptide. Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin-like fold. Gene sequence location is X:19570090..19577549.","JAK-STAT cascade ; GO:0007259 | non-traceable author statement <newline> JAK-STAT cascade ; GO:0007259 | inferred from genetic interaction with Stat92E AND inferred from genetic interaction with os <newline> blastoderm segmentation ; GO:0007350 | inferred from mutant phenotype <newline> open tracheal system development ; GO:0007424 | inferred from mutant phenotype <newline> JAK-STAT cascade ; GO:0007259 | inferred from genetic interaction with hop AND inferred from genetic interaction with os <newline> morphogenesis of an epithelium ; GO:0002009 | inferred from mutant phenotype <newline> border follicle cell migration ; GO:0007298 | inferred from mutant phenotype <newline> protein dephosphorylation ; GO:0006470 | non-traceable author statement <newline> blastoderm segmentation ; GO:0007350 | non-traceable author statement <newline> open tracheal system development ; GO:0007424 | non-traceable author statement <newline> JAK-STAT cascade ; GO:0007259 | traceable author statement <newline> hindgut morphogenesis ; GO:0007442 | inferred from mutant phenotype <newline> epithelial cell fate determination, open tracheal system ; GO:0007425 | traceable author statement <newline> immune response ; GO:0006955 | traceable author statement <newline> compound eye morphogenesis ; GO:0001745 | inferred from mutant phenotype","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with HGNC_gene:CNTFR; HGNC:2170; OMIM:118946 AND inferred from sequence or structural similarity with HGNC_gene:LIFR; HGNC:6597; OMIM:151443 <newline> plasma membrane ; GO:0005886 | non-traceable author statement <newline> apicolateral plasma membrane ; GO:0016327 | inferred from direct assay <newline> apical plasma membrane ; GO:0016324 | traceable author statement","transmembrane receptor activity ; GO:0004888 | inferred from genetic interaction with os AND inferred from sequence or structural similarity with HGNC_gene:CNTFR; HGNC:2170; OMIM:118946 AND inferred from sequence or structural similarity with HGNC_gene:LIFR; HGNC:6597; OMIM:151443 AND inferred from sequence or structural similarity with MGD:Cntfr; MGI:MGI:99605 AND inferred from sequence or structural similarity with MGD:Lifr; MGI:MGI:96788 <newline> protein tyrosine phosphatase activity ; GO:0004725 | non-traceable author statement <newline> transmembrane receptor activity ; GO:0004888 | traceable author statement <newline> cytokine binding ; GO:0019955 | non-traceable author statement"]
[null,"FBgn0024944","Octopamine receptor in mushroom bodies","Oamb","The gene Octopamine receptor in mushroom bodies is referred to in FlyBase by the symbol Dmel\\Oamb (CG3856, FBgn0024944). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: octopamine receptor activity. There is experimental evidence that it is involved in the biological process</span>: ovulation; elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger. 24 alleles are reported. The phenotype of these alleles is annotated with: ovariole. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: 7TM GPCR, rhodopsin-like; GPCR, rhodopsin-like superfamily. Gene sequence location is 3R:16514740..16540263.","ovulation ; GO:0030728 | inferred from mutant phenotype <newline> G-protein signaling, coupled to cAMP nucleotide second messenger ; GO:0007188 | NOT inferred from direct assay <newline> elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger ; GO:0051482 | inferred from direct assay <newline> octopamine or tyramine signaling pathway ; GO:0007211 | inferred from sequence or structural similarity","plasma membrane ; GO:0005886 | non-traceable author statement <newline> integral to plasma membrane ; GO:0005887 | inferred by curator from GO:0004989 <newline> integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276","octopamine receptor activity ; GO:0004989 | non-traceable author statement <newline> G-protein coupled amine receptor activity ; GO:0008227 | inferred from sequence or structural similarity <newline> octopamine receptor activity ; GO:0004989 | inferred from direct assay"]
[null,"FBgn0260660","multiplexin","mp","The gene multiplexin is referred to in FlyBase by the symbol Dmel\\mp (CG42543, FBgn0260660). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding; structural molecule activity. There is experimental evidence that it is involved in the biological process</span>: motor axon guidance. 16 alleles are reported. The phenotypes of these alleles are annotated with: intersegmental nerve; ISNb; embryonic nervous system. It has 11 annotated transcripts and 11 annotated polypeptides. Protein features are: C-type lectin fold; C-type lectin-like; Collagen triple helix repeat; Collagenase NC10/endostatin. Gene sequence location is 3L:6992568..7045670.",null,"motor axon guidance ; GO:0008045 | inferred from mutant phenotype <newline> cell adhesion ; GO:0007155 | inferred from electronic annotation with InterPro:IPR010515","collagen ; GO:0005581 | inferred from sequence or structural similarity <newline> extracellular matrix ; GO:0031012 | inferred from electronic annotation with InterPro:IPR010515","binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR016186, InterPro:IPR016187 <newline> structural molecule activity ; GO:0005198 | inferred from electronic annotation with InterPro:IPR010515"]

{"sheet":"Sheet-5 Unkwn function","index":4,"n_rows":321,"n_cols":8,"rows_kept":321,"merged":[[0,1,0,5]],"flags":["formulas_cached_only"]}
[null,"Unknown/ Uncategorized Function"]
[]
["Flybase ID","NAME","SYMBOL","Summary of gene function from Flybase","GO_BIOLOGICAL_PROCESS","GO_CELLULAR_COMPONENT","GO_MOLECULAR_FUNCTION"]
["FBgn0064640","-","Dere\\GG25244","This gene is referred to in FlyBase by the symbol Dere\\GG25244 (GG25244, FBgn0064640). It is a protein_coding_gene from Drosophila erecta. Its sequence location is scaffold_4929:8520890..8521341. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: unfolded protein binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: protein folding. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002777","prefoldin complex ; GO:0016272 | inferred from electronic annotation with InterPro:IPR002777","unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR002777"]
["FBgn0106188","-","Dere\\GG13925","This gene is referred to in FlyBase by the symbol Dere\\GG13925 (GG13925, FBgn0106188). It is a protein_coding_gene from Drosophila erecta. Its sequence location is scaffold_4784:11320454..11321479. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0064528","-","Dlit\\CG9895","This gene is referred to in FlyBase by the symbol Dlit\\CG9895 (FBgn0064528). It is a gene from Drosophila littoralis. It has not been localized to the genome sequence. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: nucleic acid binding; zinc ion binding. The biological processes in which it is involved are not known. No alleles are reported..","-","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087"]
["FBgn0064534","-","Dlit\\CG30421","This gene is referred to in FlyBase by the symbol Dlit\\CG30421 (FBgn0064534). It is a gene from Drosophila littoralis. It has not been localized to the genome sequence. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: ubiquitin thiolesterase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: ubiquitin-dependent protein catabolic process. No alleles are reported..","ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR001394, InterPro:IPR018200","-","ubiquitin thiolesterase activity ; GO:0004221 | inferred from electronic annotation with InterPro:IPR001394, InterPro:IPR018200"]
["FBgn0260198","-","Dmau\\CG4766","This gene is referred to in FlyBase by the symbol Dmau\\CG4766 (FBgn0260198). It is a gene from Drosophila mauritiana. It has not been localized to the genome sequence. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported..","-","-","-"]
["FBgn0000036","nicotinic Acetylcholine Receptor alpha 96Aa","nAcRalpha-96Aa","The gene nicotinic Acetylcholine Receptor alpha 96Aa is referred to in FlyBase by the symbol Dmel\\nAcR?-96Aa (CG5610, FBgn0000036). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:20226948..20282651. It has the cytological map location 96A1-96A2. Based on sequence similarity, it is predicted to have molecular function</span>: nicotinic acetylcholine-activated cation-selective channel activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: ion transport. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","ion transport ; GO:0006811 | inferred from electronic annotation with InterPro:IPR002394, InterPro:IPR006029, InterPro:IPR006201, InterPro:IPR018000","integral to plasma membrane ; GO:0005887 | non-traceable author statement <newline> nicotinic acetylcholine-gated receptor-channel complex ; GO:0005892 | inferred from sequence or structural similarity <newline> integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002394, InterPro:IPR006201, InterPro:IPR018000 <newline> postsynaptic membrane ; GO:0045211 | inferred from electronic annotation with InterPro:IPR002394, InterPro:IPR018000","nicotinic acetylcholine-activated cation-selective channel activity ; GO:0004889 | inferred from sequence or structural similarity <newline> nicotinic acetylcholine-activated cation-selective channel activity ; GO:0004889 | inferred from electronic annotation with InterPro:IPR002394"]
["FBgn0001223","Heat shock protein 22","Hsp22","The gene Heat shock protein 22 is referred to in FlyBase by the symbol Dmel\\Hsp22 (CG4460, FBgn0001223). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9366031..9368064. It has the cytological map location 67B2. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: determination of adult lifespan; response to oxidative stress; response to heat. 11 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> response to heat ; GO:0009408 | inferred from sequence or structural similarity with EMBL:U96099 <newline> protein refolding ; GO:0042026 | non-traceable author statement <newline> response to heat ; GO:0009408 | non-traceable author statement <newline> response to oxidative stress ; GO:0006979 | inferred from mutant phenotype <newline> response to heat ; GO:0009408 | inferred from mutant phenotype","-","-"]
["FBgn0002283","lethal (3) 73Ah","l(3)73Ah","The gene lethal (3) 73Ah is referred to in FlyBase by the symbol Dmel\\l(3)73Ah (CG4195, FBgn0002283). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:16581017..16583234. It has the cytological map location 73A10. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; zinc ion binding. The biological processes in which it is involved are not known. 7 alleles are reported. The phenotype of these alleles is annotated with: adult abdomen. It has one annotated transcript and one annotated polypeptide.","-","-","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR001841 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841"]
["FBgn0004876","center divider","cdi","The gene center divider is referred to in FlyBase by the symbol Dmel\\cdi (CG6027, FBgn0004876). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:14870604..14920076. It has the cytological map location 91E4-91F1. Based on sequence similarity, it is predicted to have molecular function</span>: protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: embryonic development via the syncytial blastoderm. 46 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; embryonic head; embryonic segment; macrochaeta; intersegmental nerve; nervous system; segment; head. It has one annotated transcript and one annotated polypeptide.","embryonic development via the syncytial blastoderm ; GO:0001700 | inferred from mutant phenotype <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from sequence or structural similarity <newline> protein amino acid phosphorylation ; GO:0006468 | non-traceable author statement <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR017441","-","protein serine/threonine kinase activity ; GO:0004674 | non-traceable author statement <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity <newline> protein kinase activity ; GO:0004672 | non-traceable author statement <newline> protein serine/threonine kinase activity ; GO:0004674 | inferred from sequence or structural similarity with UniProtKB:Q63572 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR001245, InterPro:IPR008266, InterPro:IPR017441 <newline> protein tyrosine kinase activity ; GO:0004713 | inferred from electronic annotation with InterPro:IPR008266"]
["FBgn0005670","Cytochrome P450-4d1","Cyp4d1","The gene Cytochrome P450-4d1 is referred to in FlyBase by the symbol Dmel\\Cyp4d1 (CG3656, FBgn0005670). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2053175..2056160. It has the cytological map location 2D5-2D6. Based on sequence similarity, it is predicted to have molecular function</span>: electron carrier activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction. 9 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002401","lipid particle ; GO:0005811 | inferred from direct assay <newline> microsome ; GO:0005792 | non-traceable author statement <newline> membrane ; GO:0016020 | non-traceable author statement","electron carrier activity ; GO:0009055 | non-traceable author statement <newline> electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity <newline> electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR001128 <newline> heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 <newline> monooxygenase activity ; GO:0004497 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401"]
["FBgn0010438","mitochondrial single stranded DNA-binding protein","mtSSB","The gene mitochondrial single stranded DNA-binding protein is referred to in FlyBase by the symbol Dmel\\mtSSB (CG4337, FBgn0010438). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12029912..12030973. It has the cytological map location 89B7. Based on sequence similarity, it is predicted to have molecular function</span>: single-stranded DNA binding. There is experimental evidence that it is involved in the biological process</span>: mitochondrial genome maintenance. 10 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","mitochondrial genome maintenance ; GO:0000002 | inferred from mutant phenotype <newline> mitochondrial genome maintenance ; GO:0000002 | non-traceable author statement <newline> DNA replication ; GO:0006260 | inferred from electronic annotation with InterPro:IPR011344","mitochondrial chromosome ; GO:0000262 | inferred from direct assay <newline> mitochondrion ; GO:0005739 | non-traceable author statement <newline> mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q04837","single-stranded DNA binding ; GO:0003697 | non-traceable author statement <newline> single-stranded DNA binding ; GO:0003697 | inferred from sequence or structural similarity with UniProtKB:P28042 <newline> single-stranded DNA binding ; GO:0003697 | inferred from sequence or structural similarity with UniProtKB:Q04837"]
["FBgn0011335","lethal (3) j2D3","l(3)j2D3","The gene lethal (3) j2D3 is referred to in FlyBase by the symbol Dmel\\l(3)j2D3 (CG6801, FBgn0011335). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:12109236..12111156. It has the cytological map location 68F3. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0011770","GIP-like","Gip","The gene GIP-like is referred to in FlyBase by the symbol Dmel\\Gip (CG2227, FBgn0011770). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:10222910..10223882. It has the cytological map location 9B7. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0013576","l(3)82Fd","l(3)82Fd","The gene l(3)82Fd is referred to in FlyBase by the symbol Dmel\\l(3)82Fd (CG32464, FBgn0013576). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1098665..1176165. It has the cytological map location 82F8-82F10. Its molecular function is unknown. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: cell wall macromolecule catabolic process. 22 alleles are reported. The phenotype of these alleles is annotated with: pigment cell. It has 19 annotated transcripts and 19 annotated polypeptides.","cell wall macromolecule catabolic process ; GO:0016998 | inferred from electronic annotation with InterPro:IPR002482, InterPro:IPR018392","-","-"]
["FBgn0016754","six-banded","sba","The gene six-banded is referred to in FlyBase by the symbol Dmel\\sba (CG13598, FBgn0016754). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19719889..19748695. It has the cytological map location 95C9-95C12. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: DNA binding. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR001739","DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001739, InterPro:IPR016177"]
["FBgn0020280","labial associated factor","laf","The gene labial associated factor is referred to in FlyBase by the symbol Dmel\\laf (CG14660, FBgn0020280). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:701727..704255. It has the cytological map location 82E1. Its molecular function is unknown. It is reported to be involved in the biological process</span>: embryonic development via the syncytial blastoderm. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","embryonic development via the syncytial blastoderm ; GO:0001700 | non-traceable author statement","nucleus ; GO:0005634 | non-traceable author statement","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0020304","drongo","drongo","The gene drongo is referred to in FlyBase by the symbol Dmel\\drongo (CG3365, FBgn0020304). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:833584..851096. It has the cytological map location 21E2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: ARF GTPase activator activity; zinc ion binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: regulation of ARF GTPase activity. 8 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides.","regulation of ARF GTPase activity ; GO:0032312 | inferred from electronic annotation with InterPro:IPR001164","-","ARF GTPase activator activity ; GO:0008060 | inferred from electronic annotation with InterPro:IPR001164 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001164"]
["FBgn0020367","Vha68-2","Vha68-2","The gene Vha68-2 is referred to in FlyBase by the symbol Dmel\\Vha68-2 (CG3762, FBgn0020367). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12974322..12978615. It has the cytological map location 34A3. Based on sequence similarity, it is predicted to have molecular function</span>: hydrogen-exporting ATPase activity, phosphorylative mechanism. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: ATP synthesis coupled proton transport. 16 alleles are reported. The phenotype of these alleles is annotated with: larval Malpighian tubule. It has 3 annotated transcripts and 3 annotated polypeptides.","ATP synthesis coupled proton transport ; GO:0015986 | inferred from electronic annotation with InterPro:IPR000793, InterPro:IPR005725","vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | non-traceable author statement <newline> vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221 | inferred from sequence or structural similarity with SGD_LOCUS:TFP1; SGD:S0002344","hydrogen-exporting ATPase activity, phosphorylative mechanism ; GO:0008553 | non-traceable author statement <newline> hydrogen-exporting ATPase activity, phosphorylative mechanism ; GO:0008553 | inferred from sequence or structural similarity with SGD_LOCUS:TFP1; SGD:S0002344 <newline> proton-transporting ATPase activity, rotational mechanism ; GO:0046961 | inferred from electronic annotation with InterPro:IPR004100, InterPro:IPR005725, InterPro:IPR018118 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000194, InterPro:IPR020003 <newline> hydrogen ion transporting ATP synthase activity, rotational mechanism ; GO:0046933 | inferred from electronic annotation with InterPro:IPR004100, InterPro:IPR005725, InterPro:IPR018118"]
["FBgn0023526","-","CG2865","This gene is referred to in FlyBase by the symbol Dmel\\CG2865 (CG2865, FBgn0023526). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2175545..2186779. It has the cytological map location 2F4-2F5. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0026263","bip1","bip1","The gene bip1 is referred to in FlyBase by the symbol Dmel\\bip1 (CG7574, FBgn0026263). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:8047433..8051811. It has the cytological map location 66B3. It is reported to have molecular function</span>: protein binding. The biological processes in which it is involved are not known. 12 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","biological_process ; GO:0008150 | no biological data available","nucleus ; GO:0005634 | non-traceable author statement","protein binding ; GO:0005515 | non-traceable author statement"]
["FBgn0027546","-","CG4766","This gene is referred to in FlyBase by the symbol Dmel\\CG4766 (CG4766, FBgn0027546). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:5891537..5894830. It has the cytological map location 5D1-5D2. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0027579","-","CG5508","This gene is referred to in FlyBase by the symbol Dmel\\CG5508 (CG5508, FBgn0027579). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:23750915..23758844. It has the cytological map location 98B6. Based on sequence similarity, it is predicted to have molecular function</span>: glycerol-3-phosphate O-acyltransferase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: plasma membrane organization; phospholipid biosynthetic process. 8 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","phospholipid biosynthetic process ; GO:0008654 | inferred from sequence or structural similarity with UniProtKB:Q9HCL2 <newline> plasma membrane organization ; GO:0007009 | inferred from sequence or structural similarity with UniProtKB:Q9HCL2","mitochondrial outer membrane ; GO:0005741 | inferred from sequence or structural similarity with UniProtKB:Q9HCL2","glycerol-3-phosphate O-acyltransferase activity ; GO:0004366 | inferred from sequence or structural similarity with UniProtKB:P97564 <newline> glycerol-3-phosphate O-acyltransferase activity ; GO:0004366 | inferred from sequence or structural similarity with UniProtKB:Q9HCL2"]
["FBgn0027621","6-phosphofructo-2-kinase","Pfrx","The gene 6-phosphofructo-2-kinase is referred to in FlyBase by the symbol Dmel\\Pfrx (CG3400, FBgn0027621). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:19389538..19403390. It has the cytological map location 18C8. Based on sequence similarity, it is predicted to have molecular function</span>: fructose-2,6-bisphosphate 2-phosphatase activity; 6-phosphofructo-2-kinase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: fructose metabolic process. 33 alleles are reported. No phenotypic data is available. It has 8 annotated transcripts and 8 annotated polypeptides.","fructose metabolic process ; GO:0006000 | inferred from sequence or structural similarity with UniProtKB:P07953 <newline> fructose 2,6-bisphosphate metabolic process ; GO:0006003 | inferred from electronic annotation with InterPro:IPR003094","-","6-phosphofructo-2-kinase activity ; GO:0003873 | inferred from sequence or structural similarity with UniProtKB:P07953 <newline> fructose-2,6-bisphosphate 2-phosphatase activity ; GO:0004331 | inferred from sequence or structural similarity with UniProtKB:P07953 <newline> 6-phosphofructo-2-kinase activity ; GO:0003873 | non-traceable author statement <newline> fructose-2,6-bisphosphate 2-phosphatase activity ; GO:0004331 | non-traceable author statement <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003094, InterPro:IPR013079"]
["FBgn0028579","phtf","phtf","The gene phtf is referred to in FlyBase by the symbol Dmel\\phtf (CG3268, FBgn0028579). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:2629372..2633649. It has the cytological map location 42C7. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0028642","espinas","esn","The gene espinas is referred to in FlyBase by the symbol Dmel\\esn (CG12833, FBgn0028642). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:2973819..3015375. It has the cytological map location 42F1-42F2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781, InterPro:IPR010442"]
["FBgn0028878","-","CG15269","This gene is referred to in FlyBase by the symbol Dmel\\CG15269 (CG15269, FBgn0028878). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:15109585..15112914. It has the cytological map location 35C2. Based on sequence similarity, it is predicted to have molecular function</span>: nucleic acid binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","nucleic acid binding ; GO:0003676 | inferred from sequence or structural similarity with EMBL:X89264 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
["FBgn0029003","mab-21","mab-21","The gene mab-21 is referred to in FlyBase by the symbol Dmel\\mab-21 (CG4746, FBgn0029003). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:5902216..5907211. It has the cytological map location 5D2. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0029823","-","CG3011","This gene is referred to in FlyBase by the symbol Dmel\\CG3011 (CG3011, FBgn0029823). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:5807099..5810826. It has the cytological map location 5C7. Based on sequence similarity, it is predicted to have molecular function</span>: glycine hydroxymethyltransferase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: L-serine biosynthetic process. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","L-serine biosynthetic process ; GO:0006564 | inferred from sequence or structural similarity with UniProtKB:P34897 <newline> glycine metabolic process ; GO:0006544 | inferred from electronic annotation with InterPro:IPR001085, InterPro:IPR019798","mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P34897","glycine hydroxymethyltransferase activity ; GO:0004372 | inferred from sequence or structural similarity with UniProtKB:P35623 <newline> glycine hydroxymethyltransferase activity ; GO:0004372 | inferred from sequence or structural similarity with UniProtKB:P34897 <newline> pyridoxal phosphate binding ; GO:0030170 | inferred from electronic annotation with InterPro:IPR015421, InterPro:IPR019798"]
["FBgn0029824","-","CG3726","This gene is referred to in FlyBase by the symbol Dmel\\CG3726 (CG3726, FBgn0029824). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:5811210..5835703. It has the cytological map location 5C7-5C10. It is reported to have molecular function</span>: DNA binding. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","DNA binding ; GO:0003677 | non-traceable author statement <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR011526, InterPro:IPR017956 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000210, InterPro:IPR011333, InterPro:IPR013069"]
["FBgn0029831","-","CG5966","This gene is referred to in FlyBase by the symbol Dmel\\CG5966 (CG5966, FBgn0029831). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:5882845..5886677. It has the cytological map location 5D1. Based on sequence similarity, it is predicted to have molecular function</span>: triglyceride lipase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: lipid metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","lipid metabolic process ; GO:0006629 | inferred from electronic annotation with InterPro:IPR000734, InterPro:IPR002331","-","triglyceride lipase activity ; GO:0004806 | inferred from sequence or structural similarity with UniProtKB:P27657"]
["FBgn0030073","-","CG10962","This gene is referred to in FlyBase by the symbol Dmel\\CG10962 (CG10962, FBgn0030073). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8866940..8943020. It has the cytological map location 8C1-8C4. Based on sequence similarity, it is predicted to have molecular function</span>: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction. 36 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002347","-","oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ; GO:0016616 | inferred from sequence or structural similarity with EMBL:AJ000671; protein_id:CAA04227 <newline> binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR016040"]
["FBgn0030311","-","CG11699","This gene is referred to in FlyBase by the symbol Dmel\\CG11699 (CG11699, FBgn0030311). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11464657..11465445. It has the cytological map location 10C6. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0030569","-","CG9411","This gene is referred to in FlyBase by the symbol Dmel\\CG9411 (CG9411, FBgn0030569). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:14366436..14374112. It has the cytological map location 12E10. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0030616","Ribosomal protein L37a","RpL37a","The gene Ribosomal protein L37a is referred to in FlyBase by the symbol Dmel\\RpL37a (CG9091, FBgn0030616). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15032358..15033423. It has the cytological map location 13B1. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of ribosome. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","translation ; GO:0006412 | inferred from sequence or structural similarity with NCBI_gi:4506641","ribosome ; GO:0005840 | non-traceable author statement <newline> cytosolic large ribosomal subunit ; GO:0022625 | inferred from sequence or structural similarity with NCBI_gi:4506641","structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with NCBI_gi:4506641 <newline> structural constituent of ribosome ; GO:0003735 | non-traceable author statement"]
["FBgn0030646","-","CG9203","This gene is referred to in FlyBase by the symbol Dmel\\CG9203 (CG9203, FBgn0030646). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15366927..15369410. It has the cytological map location 13C4-13C5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: DNA binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: DNA repair. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","DNA repair ; GO:0006281 | inferred from electronic annotation with InterPro:IPR006642","-","DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006642"]
["FBgn0030718","-","CG9172","This gene is referred to in FlyBase by the symbol Dmel\\CG9172 (CG9172, FBgn0030718). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15879882..15880839. It has the cytological map location 14A5. Based on sequence similarity, it is predicted to have molecular function</span>: NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, NADH to ubiquinone. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O75251","mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:P42026 <newline> mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O75251","NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from sequence or structural similarity with UniProtKB:P42026 <newline> NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O75251 <newline> 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR006137, InterPro:IPR006138, InterPro:IPR014406 <newline> quinone binding ; GO:0048038 | inferred from electronic annotation with InterPro:IPR006137, InterPro:IPR006138"]
["FBgn0030757","-","CG9902","This gene is referred to in FlyBase by the symbol Dmel\\CG9902 (CG9902, FBgn0030757). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16437585..16441519. It has the cytological map location 14E1. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0030912","-","CG6023","This gene is referred to in FlyBase by the symbol Dmel\\CG6023 (CG6023, FBgn0030912). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:18208156..18215198. It has the cytological map location 17A5. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","-","-"]
["FBgn0031011","-","CG8034","This gene is referred to in FlyBase by the symbol Dmel\\CG8034 (CG8034, FBgn0031011). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:19176553..19191753. It has the cytological map location 18B9-18C1. Its molecular function is unknown. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR011701","-","-"]
["FBgn0031020","Nat1","Nat1","The gene Nat1 is referred to in FlyBase by the symbol Dmel\\Nat1 (CG12202, FBgn0031020). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:19374186..19378676. It has the cytological map location 18C7. Based on sequence similarity, it is predicted to have molecular function</span>: peptide alpha-N-acetyltransferase activity. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","peptide alpha-N-acetyltransferase activity ; GO:0004596 | inferred from sequence or structural similarity with EMBL:AL023781 <newline> binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR011990"]
["FBgn0031126","Cyp6v1","Cyp6v1","The gene Cyp6v1 is referred to in FlyBase by the symbol Dmel\\Cyp6v1 (CG1829, FBgn0031126). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:20528811..20532419. It has the cytological map location 19E1. Based on sequence similarity, it is predicted to have molecular function</span>: electron carrier activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002401","microsome ; GO:0005792 | non-traceable author statement <newline> membrane ; GO:0016020 | non-traceable author statement","electron carrier activity ; GO:0009055 | non-traceable author statement <newline> electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity <newline> electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR001128 <newline> heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401 <newline> monooxygenase activity ; GO:0004497 | inferred from electronic annotation with InterPro:IPR001128, InterPro:IPR002401"]
["FBgn0031129","-","CG1324","This gene is referred to in FlyBase by the symbol Dmel\\CG1324 (CG1324, FBgn0031129). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:20605771..20606987. It has the cytological map location 19E2. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0031429","-","CG15393","This gene is referred to in FlyBase by the symbol Dmel\\CG15393 (CG15393, FBgn0031429). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:2489754..2490119. It has the cytological map location 22F3. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0031488","-","CG17265","This gene is referred to in FlyBase by the symbol Dmel\\CG17265 (CG17265, FBgn0031488). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:3013501..3016069. It has the cytological map location 23C4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: RNA interference. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","RNA interference ; GO:0016246 | inferred from mutant phenotype","-","-"]
["FBgn0031897","-","CG13784","This gene is referred to in FlyBase by the symbol Dmel\\CG13784 (CG13784, FBgn0031897). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:7205250..7220029. It has the cytological map location 27E4-27E5. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","-","-"]
["FBgn0032153","-","CG4537","This gene is referred to in FlyBase by the symbol Dmel\\CG4537 (CG4537, FBgn0032153). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:9890885..9891336. It has the cytological map location 30E1. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0032299","-","CG17127","This gene is referred to in FlyBase by the symbol Dmel\\CG17127 (CG17127, FBgn0032299). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:10770867..10771370. It has the cytological map location 32A5. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","-","-"]
["FBgn0032629","beat-IIIc","beat-IIIc","The gene beat-IIIc is referred to in FlyBase by the symbol Dmel\\beat-IIIc (CG15138, FBgn0032629). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:17189810..17260732. It has the cytological map location 36C2-36C4. Its molecular function is unknown. The biological processes in which it is involved are not known. 11 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","extracellular region ; GO:0005576 | non-traceable author statement","-"]
["FBgn0032685","-","CG10211","This gene is referred to in FlyBase by the symbol Dmel\\CG10211 (CG10211, FBgn0032685). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:18517493..18531782. It has the cytological map location 36F6. Based on sequence similarity, it is predicted to have molecular function</span>: peroxidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction; response to oxidative stress. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002007, InterPro:IPR010255, InterPro:IPR019791 <newline> response to oxidative stress ; GO:0006979 | inferred from electronic annotation with InterPro:IPR002007, InterPro:IPR010255, InterPro:IPR019791","-","peroxidase activity ; GO:0004601 | inferred from sequence or structural similarity with MGD:Mpo; MGI:MGI:97137 <newline> heme binding ; GO:0020037 | inferred from electronic annotation with InterPro:IPR002007, InterPro:IPR010255, InterPro:IPR019791"]
["FBgn0032694","Misexpression suppressor of ras 3","MESR3","The gene Misexpression suppressor of ras 3 is referred to in FlyBase by the symbol Dmel\\MESR3 (CG15162, FBgn0032694). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:18617257..18661787. It has the cytological map location 36F7-36F9. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0032724","-","CG10428","This gene is referred to in FlyBase by the symbol Dmel\\CG10428 (CG10428, FBgn0032724). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:18948897..18950973. It has the cytological map location 37B6-37B7. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: methyltransferase activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR007848"]
["FBgn0033160","-","CG11107","This gene is referred to in FlyBase by the symbol Dmel\\CG11107 (CG11107, FBgn0033160). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3274719..3278529. It has the cytological map location 43B2. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent helicase activity; ATP-dependent RNA helicase activity; RNA helicase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nuclear mRNA splicing, via spliceosome. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","nuclear mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with NCBI_NP:011395 AND inferred from sequence or structural similarity with SGD_LOCUS:PRP43; SGD:S0003088 <newline> nuclear mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011|GO:0071013","spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with SGD_LOCUS:PRP43; SGD:S0003088 <newline> precatalytic spliceosome ; GO:0071011 | inferred from direct assay <newline> catalytic step 2 spliceosome ; GO:0071013 | inferred from direct assay","RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity <newline> ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD_LOCUS:PRP43; SGD:S0003088 <newline> ATP-dependent helicase activity ; GO:0008026 | inferred from sequence or structural similarity with EMBL:AB001636 <newline> RNA helicase activity ; GO:0003724 | inferred from sequence or structural similarity with NCBI_NP:011395 AND inferred from sequence or structural similarity with SGD_LOCUS:PRP43; SGD:S0003088 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001650, InterPro:IPR011545 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001650, InterPro:IPR011545"]
["FBgn0033244","-","CG8726","This gene is referred to in FlyBase by the symbol Dmel\\CG8726 (CG8726, FBgn0033244). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3855634..3859554. It has the cytological map location 43F9. It is reported to have molecular function</span>: protein kinase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: cell communication; protein amino acid phosphorylation. 2 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","cell communication ; GO:0007154 | inferred from electronic annotation with InterPro:IPR001683 <newline> protein amino acid phosphorylation ; GO:0006468 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017442","-","protein kinase activity ; GO:0004672 | non-traceable author statement <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017442 <newline> protein kinase activity ; GO:0004672 | inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017442 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR001683 <newline> phosphoinositide binding ; GO:0035091 | inferred from electronic annotation with InterPro:IPR001683"]
["FBgn0033355","-","CG13748","This gene is referred to in FlyBase by the symbol Dmel\\CG13748 (CG13748, FBgn0033355). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4827920..4828641. It has the cytological map location 44F9. Based on sequence similarity, it is predicted to have molecular function</span>: serine-type endopeptidase inhibitor activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","serine-type endopeptidase inhibitor activity ; GO:0004867 | inferred from sequence or structural similarity with EMBL:AF099016; protein_id:AAD22172.1"]
["FBgn0033467","-","CG15863","This gene is referred to in FlyBase by the symbol Dmel\\CG15863 (CG15863, FBgn0033467). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:5846624..5848459. It has the cytological map location 46C7. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: unfolded protein binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: protein folding. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR002777","prefoldin complex ; GO:0016272 | inferred from electronic annotation with InterPro:IPR002777","unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR002777"]
["FBgn0033486","-","CG11866","This gene is referred to in FlyBase by the symbol Dmel\\CG11866 (CG11866, FBgn0033486). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6005198..6008956. It has the cytological map location 46F1. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0033521","-","CG12896","This gene is referred to in FlyBase by the symbol Dmel\\CG12896 (CG12896, FBgn0033521). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6314385..6315418. It has the cytological map location 47A7. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: antioxidant activity; peroxiredoxin activity. There is experimental evidence that it is involved in the biological process</span>: mesoderm development. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","mesoderm development ; GO:0007498 | inferred from expression pattern <newline> cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR017936","-","peroxiredoxin activity ; GO:0051920 | inferred from electronic annotation with InterPro:IPR019479 <newline> antioxidant activity ; GO:0016209 | inferred from electronic annotation with InterPro:IPR000866"]
["FBgn0034091","mrj","mrj","The gene mrj is referred to in FlyBase by the symbol Dmel\\mrj (CG8448, FBgn0034091). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12090827..12109301. It has the cytological map location 52F8-52F11. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: heat shock protein binding. The biological processes in which it is involved are not known. 21 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides.","-","-","heat shock protein binding ; GO:0031072 | inferred from electronic annotation with InterPro:IPR001623, InterPro:IPR018253"]
["FBgn0034127","-","CG7848","This gene is referred to in FlyBase by the symbol Dmel\\CG7848 (CG7848, FBgn0034127). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12321353..12323459. It has the cytological map location 53C4. Based on sequence similarity, it is predicted to have molecular function</span>: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: malate metabolic process. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","malate metabolic process ; GO:0006108 | inferred from electronic annotation with InterPro:IPR001891","-","malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity ; GO:0004473 | inferred from sequence or structural similarity with NCBI_gi:4505143 <newline> NAD or NADH binding ; GO:0051287 | inferred from electronic annotation with InterPro:IPR012302"]
["FBgn0034145","-","CG5065","This gene is referred to in FlyBase by the symbol Dmel\\CG5065 (CG5065, FBgn0034145). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12495175..12511214. It has the cytological map location 53C11-53C12. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding; catalytic activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 7 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR016040","-","catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR016040 <newline> binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR016040"]
["FBgn0034187","-","CG6967","This gene is referred to in FlyBase by the symbol Dmel\\CG6967 (CG6967, FBgn0034187). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12950282..12954051. It has the cytological map location 53F4. Its molecular function is unknown. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ; GO:0000184 | inferred from sequence or structural similarity with EMBL:AF074017","-","-"]
["FBgn0034321","-","CG14502","This gene is referred to in FlyBase by the symbol Dmel\\CG14502 (CG14502, FBgn0034321). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14176593..14182217. It has the cytological map location 55C2. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","-","-","-"]
["FBgn0034408","serrano","sano","The gene serrano is referred to in FlyBase by the symbol Dmel\\sano (CG12758, FBgn0034408). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:14765899..14847000. It has the cytological map location 55F8-56A1. Its molecular function is unknown. The biological processes in which it is involved are not known. 16 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0034436","-","CG11961","This gene is referred to in FlyBase by the symbol Dmel\\CG11961 (CG11961, FBgn0034436). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15245236..15249878. It has the cytological map location 56D1-56D2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: peptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR007484","-","peptidase activity ; GO:0008233 | inferred from electronic annotation with InterPro:IPR007484"]
["FBgn0034478","-","CG10822","This gene is referred to in FlyBase by the symbol Dmel\\CG10822 (CG10822, FBgn0034478). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15838938..15839456. It has the cytological map location 56E5. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled. Based on sequence similarity, it is predicted to be involved in the biological process</span>: microtubule-based movement. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","microtubule-based movement ; GO:0007018 | inferred from sequence or structural similarity","dynein complex ; GO:0030286 | inferred from sequence or structural similarity","ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity"]
["FBgn0034481","-","CG11041","This gene is referred to in FlyBase by the symbol Dmel\\CG11041 (CG11041, FBgn0034481). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:16033638..16034329. It has the cytological map location 56F8. Based on sequence similarity, it is predicted to have molecular function</span>: calcium ion binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with UniProtKB:P02593"]
["FBgn0034500","-","CG11200","This gene is referred to in FlyBase by the symbol Dmel\\CG11200 (CG11200, FBgn0034500). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:16192022..16196170. It has the cytological map location 56F16. Based on sequence similarity, it is predicted to have molecular function</span>: carbonyl reductase (NADPH) activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002347","-","carbonyl reductase (NADPH) activity ; GO:0004090 | inferred from sequence or structural similarity with MGD:Cbr1; MGI:MGI:88284 <newline> binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR016040"]
["FBgn0034706","-","CG11275","This gene is referred to in FlyBase by the symbol Dmel\\CG11275 (CG11275, FBgn0034706). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18067198..18070155. It has the cytological map location 58C5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000210, InterPro:IPR011333, InterPro:IPR013069"]
["FBgn0034718","windpipe","wdp","The gene windpipe is referred to in FlyBase by the symbol Dmel\\wdp (CG3413, FBgn0034718). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18185718..18199425. It has the cytological map location 58D3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides.","-","plasma membrane ; GO:0005886 | non-traceable author statement","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR001611"]
["FBgn0034837","Ribosomal protein L22-like","RpL22-like","The gene Ribosomal protein L22-like is referred to in FlyBase by the symbol Dmel\\RpL22-like (CG9871, FBgn0034837). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19134115..19135360. It has the cytological map location 59D3. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of ribosome. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translation. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","translation ; GO:0006412 | inferred from sequence or structural similarity with HGNC_gene:RPL22; HGNC:10315; OMIM:180474","cytosolic large ribosomal subunit ; GO:0022625 | inferred from sequence or structural similarity with HGNC_gene:RPL22; HGNC:10315; OMIM:180474","structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with HGNC_gene:RPL22; HGNC:10315; OMIM:180474"]
["FBgn0034909","-","CG4797","This gene is referred to in FlyBase by the symbol Dmel\\CG4797 (CG4797, FBgn0034909). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19699704..19705849. It has the cytological map location 60A2. Based on sequence similarity, it is predicted to have molecular function</span>: glucose transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR005828, InterPro:IPR005829","integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828","glucose transmembrane transporter activity ; GO:0005355 | inferred from sequence or structural similarity with MGD:Slc2a3; MGI:MGI:95757"]
["FBgn0034976","-","CG4049","This gene is referred to in FlyBase by the symbol Dmel\\CG4049 (CG4049, FBgn0034976). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19995429..20001793. It has the cytological map location 60B10. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: DNA binding; ATP binding; helicase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: DNA repair. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","DNA repair ; GO:0006281 | inferred from sequence or structural similarity with SGD_LOCUS:RAD54; SGD:S0003131","-","ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000330, InterPro:IPR001650 <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR000330 <newline> helicase activity ; GO:0004386 | inferred from electronic annotation with InterPro:IPR001650"]
["FBgn0035146","-","CG13893","This gene is referred to in FlyBase by the symbol Dmel\\CG13893 (CG13893, FBgn0035146). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:599094..604001. It has the cytological map location 61C6. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transport. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR001071","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR001071","transporter activity ; GO:0005215 | inferred from electronic annotation with InterPro:IPR001071"]
["FBgn0035161","-","CG13898","This gene is referred to in FlyBase by the symbol Dmel\\CG13898 (CG13898, FBgn0035161). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:803427..804051. It has the cytological map location 61D1. Based on sequence similarity, it is predicted to have molecular function</span>: calcium ion binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with EMBL:L31642"]
["FBgn0035232","-","CG12099","This gene is referred to in FlyBase by the symbol Dmel\\CG12099 (CG12099, FBgn0035232). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:1555363..1558454. It has the cytological map location 62A5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; zinc ion binding. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","-","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR001841 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841"]
["FBgn0035376","-","CG2083","This gene is referred to in FlyBase by the symbol Dmel\\CG2083 (CG2083, FBgn0035376). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:2788122..2800130. It has the cytological map location 62F4. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087"]
["FBgn0035426","-","CG12078","This gene is referred to in FlyBase by the symbol Dmel\\CG12078 (CG12078, FBgn0035426). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:3243274..3244263. It has the cytological map location 63C1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: phosphatase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","phosphatase activity ; GO:0016791 | inferred from electronic annotation with InterPro:IPR011948"]
["FBgn0035445","-","CG12014","This gene is referred to in FlyBase by the symbol Dmel\\CG12014 (CG12014, FBgn0035445). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:3378268..3380083. It has the cytological map location 63D2. Based on sequence similarity, it is predicted to have molecular function</span>: iduronate-2-sulfatase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000917, InterPro:IPR017849, InterPro:IPR017850","-","iduronate-2-sulfatase activity ; GO:0004423 | inferred from sequence or structural similarity with UniProtKB:P22304"]
["FBgn0035455","-","CG10862","This gene is referred to in FlyBase by the symbol Dmel\\CG10862 (CG10862, FBgn0035455). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:3653465..3654771. It has the cytological map location 63E6. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquitin-protein ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: post-translational protein modification; regulation of protein metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","regulation of protein metabolic process ; GO:0051246 | inferred from electronic annotation with InterPro:IPR000608 <newline> post-translational protein modification ; GO:0043687 | inferred from electronic annotation with InterPro:IPR000608","-","ubiquitin-protein ligase activity ; GO:0004842 | inferred from sequence or structural similarity with HGNC_gene:UBE2D1; HGNC:12474; OMIM:602961"]
["FBgn0035528","-","CG15012","This gene is referred to in FlyBase by the symbol Dmel\\CG15012 (CG15012, FBgn0035528). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4291208..4292389. It has the cytological map location 64A12. Based on sequence similarity, it is predicted to have molecular function</span>: beta-N-acetylhexosaminidase activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","-","beta-N-acetylhexosaminidase activity ; GO:0004563 | inferred from sequence or structural similarity with UniProtKB:P49010"]
["FBgn0035533","Cip4","Cip4","The gene Cip4 is referred to in FlyBase by the symbol Dmel\\Cip4 (CG15015, FBgn0035533). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4323530..4364120. It has the cytological map location 64B1-64B2. Based on sequence similarity, it is predicted to have molecular function</span>: protein binding; Rho GTPase binding. There is experimental evidence that it is involved in the biological process</span>: mesoderm development. 13 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","mesoderm development ; GO:0007498 | inferred from expression pattern <newline> actin cytoskeleton organization ; GO:0030036 | inferred from sequence or structural similarity with UniProtKB:Q15642 <newline> signal transduction ; GO:0007165 | inferred from sequence or structural similarity with UniProtKB:Q15642","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR011072","protein binding ; GO:0005515 | inferred from sequence or structural similarity with UniProtKB:Q15642 <newline> Rho GTPase binding ; GO:0017048 | inferred from sequence or structural similarity with EMBL:AJ000414; protein_id:CAA04062"]
["FBgn0035542","-","CG11347","This gene is referred to in FlyBase by the symbol Dmel\\CG11347 (CG11347, FBgn0035542). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4406948..4420266. It has the cytological map location 64B4-64B5. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides.","-","-","-"]
["FBgn0035641","-","CG5568","This gene is referred to in FlyBase by the symbol Dmel\\CG5568 (CG5568, FBgn0035641). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:5864602..5866618. It has the cytological map location 64F3. Based on sequence similarity, it is predicted to have molecular function</span>: 4-coumarate-CoA ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR000873","-","4-coumarate-CoA ligase activity ; GO:0016207 | inferred from sequence or structural similarity with UniProtKB:O48869"]
["FBgn0035951","-","CG5068","This gene is referred to in FlyBase by the symbol Dmel\\CG5068 (CG5068, FBgn0035951). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:8979812..8981980. It has the cytological map location 66F1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: catalytic activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","catalytic activity ; GO:0003824 | inferred from electronic annotation with InterPro:IPR000639"]
["FBgn0035954","Dorsocross3","Doc3","The gene Dorsocross3 is referred to in FlyBase by the symbol Dmel\\Doc3 (CG5093, FBgn0035954). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:8998298..9000351. It has the cytological map location 66F1. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: cardiac cell differentiation. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","cardiac cell differentiation ; GO:0035051 | inferred from mutant phenotype <newline> regulation of transcription, DNA-dependent ; GO:0006355 | inferred from electronic annotation with InterPro:IPR001699, InterPro:IPR002070, InterPro:IPR018186","nucleus ; GO:0005634 | inferred from sequence or structural similarity with MGD:Tbx2; MGI:MGI:98494","transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with UniProtKB:O73718"]
["FBgn0035955","-","CG5194","This gene is referred to in FlyBase by the symbol Dmel\\CG5194 (CG5194, FBgn0035955). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9001724..9002951. It has the cytological map location 66F1. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0036112","-","CG14147","This gene is referred to in FlyBase by the symbol Dmel\\CG14147 (CG14147, FBgn0036112). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:10965754..10966582. It has the cytological map location 68A1. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0036115","-","CG6327","This gene is referred to in FlyBase by the symbol Dmel\\CG6327 (CG6327, FBgn0036115). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:11029458..11044469. It has the cytological map location 68A2-68A3. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides.","-","-","-"]
["FBgn0036154","-","CG6168","This gene is referred to in FlyBase by the symbol Dmel\\CG6168 (CG6168, FBgn0036154). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:11313762..11314819. It has the cytological map location 68C2. Based on sequence similarity, it is predicted to have molecular function</span>: metalloendopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: defense response to Gram-negative bacterium. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","proteolysis ; GO:0006508 | inferred from sequence or structural similarity <newline> defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype <newline> proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR007484","-","metalloendopeptidase activity ; GO:0004222 | inferred from sequence or structural similarity <newline> peptidase activity ; GO:0008233 | inferred from electronic annotation with InterPro:IPR007484"]
["FBgn0036156","-","CG11726","This gene is referred to in FlyBase by the symbol Dmel\\CG11726 (CG11726, FBgn0036156). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:11387790..11388773. It has the cytological map location 68C6. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","mRNA binding ; GO:0003729 | inferred from sequence or structural similarity <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 <newline> nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR012677"]
["FBgn0036222","-","CG5718","This gene is referred to in FlyBase by the symbol Dmel\\CG5718 (CG5718, FBgn0036222). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:11915703..11917857. It has the cytological map location 68E3. Based on sequence similarity, it is predicted to have molecular function</span>: succinate dehydrogenase (ubiquinone) activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: electron transport chain; tricarboxylic acid cycle. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","tricarboxylic acid cycle ; GO:0006099 | inferred from electronic annotation with InterPro:IPR011281 <newline> electron transport chain ; GO:0022900 | inferred from electronic annotation with InterPro:IPR014006","mitochondrial respiratory chain complex II ; GO:0005749 | inferred from sequence or structural similarity with EMBL:AF095938","succinate dehydrogenase (ubiquinone) activity ; GO:0008177 | inferred from sequence or structural similarity with EMBL:AF095938 <newline> electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR003953 <newline> FAD binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR011281, InterPro:IPR014006"]
["FBgn0036316","-","CG10960","This gene is referred to in FlyBase by the symbol Dmel\\CG10960 (CG10960, FBgn0036316). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:12817982..12836205. It has the cytological map location 69E5-69E6. Based on sequence similarity, it is predicted to have molecular function</span>: glucose transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport. 7 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR003663, InterPro:IPR005828, InterPro:IPR005829","integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828","glucose transmembrane transporter activity ; GO:0005355 | inferred from sequence or structural similarity with MGD:Slc2a2; MGI:MGI:1095438"]
["FBgn0036373","-","CG10741","This gene is referred to in FlyBase by the symbol Dmel\\CG10741 (CG10741, FBgn0036373). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:13479904..13495504. It has the cytological map location 70B2-70B3. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","-","-"]
["FBgn0036406","-","CG13484","This gene is referred to in FlyBase by the symbol Dmel\\CG13484 (CG13484, FBgn0036406). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14045528..14046179. It has the cytological map location 70D1. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0036428","-","CG9238","This gene is referred to in FlyBase by the symbol Dmel\\CG9238 (CG9238, FBgn0036428). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14534633..14544071. It has the cytological map location 70E1-70E2. Based on sequence similarity, it is predicted to have molecular function</span>: protein phosphatase type 1 regulator activity; protein phosphatase 1 binding. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","-","protein phosphatase 1 binding ; GO:0008157 | inferred from sequence or structural similarity with EMBL:U89924 <newline> protein phosphatase type 1 regulator activity ; GO:0008599 | inferred from sequence or structural similarity with NCBI_gi:4885559"]
["FBgn0036476","-","CG6945","This gene is referred to in FlyBase by the symbol Dmel\\CG6945 (CG6945, FBgn0036476). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:15083917..15087819. It has the cytological map location 71B4. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0036522","-","CG7372","This gene is referred to in FlyBase by the symbol Dmel\\CG7372 (CG7372, FBgn0036522). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:15613059..15617236. It has the cytological map location 71E3-71E4. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding; nucleic acid binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087"]
["FBgn0036577","-","CG13073","This gene is referred to in FlyBase by the symbol Dmel\\CG13073 (CG13073, FBgn0036577). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:16206151..16210403. It has the cytological map location 72D10. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0036663","-","CG9674","This gene is referred to in FlyBase by the symbol Dmel\\CG9674 (CG9674, FBgn0036663). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:16780915..16800828. It has the cytological map location 73C4-73D1. Based on sequence similarity, it is predicted to have molecular function</span>: glutamate synthase (NADPH) activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction; glutamate biosynthetic process. 13 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides.","oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001327, InterPro:IPR002489, InterPro:IPR006005, InterPro:IPR006982, InterPro:IPR009051 <newline> glutamate biosynthetic process ; GO:0006537 | inferred from electronic annotation with InterPro:IPR002932, InterPro:IPR006005, InterPro:IPR012220","-","glutamate synthase (NADPH) activity ; GO:0004355 | inferred from sequence or structural similarity with UniProtKB:Q03460 <newline> iron-sulfur cluster binding ; GO:0051536 | inferred from electronic annotation with InterPro:IPR009051, InterPro:IPR012285 <newline> FAD binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR001327, InterPro:IPR012220 <newline> FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR012220 <newline> iron ion binding ; GO:0005506 | inferred from electronic annotation with InterPro:IPR012220"]
["FBgn0036773","-","CG13698","This gene is referred to in FlyBase by the symbol Dmel\\CG13698 (CG13698, FBgn0036773). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:18082209..18099230. It has the cytological map location 75B7-75B9. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0036782","-","CG7320","This gene is referred to in FlyBase by the symbol Dmel\\CG7320 (CG7320, FBgn0036782). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:18194736..18196666. It has the cytological map location 75C2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: oxygen transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transport. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR000896, InterPro:IPR013788","-","oxygen transporter activity ; GO:0005344 | inferred from electronic annotation with InterPro:IPR000896, InterPro:IPR013788"]
["FBgn0036783","Chemosensory protein A 75a","CheA75a","The gene Chemosensory protein A 75a is referred to in FlyBase by the symbol Dmel\\CheA75a (CG7313, FBgn0036783). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:18245188..18245946. It has the cytological map location 75C2. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0036834","-","CG6836","This gene is referred to in FlyBase by the symbol Dmel\\CG6836 (CG6836, FBgn0036834). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:18943732..18948509. It has the cytological map location 75F1. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0036900","-","CG8765","This gene is referred to in FlyBase by the symbol Dmel\\CG8765 (CG8765, FBgn0036900). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19677038..19680458. It has the cytological map location 76C1. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0037153","olf413","olf413","The gene olf413 is referred to in FlyBase by the symbol Dmel\\olf413 (CG12673, FBgn0037153). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:22129216..22235892. It has the cytological map location 79C2-79D2. Based on sequence similarity, it is predicted to have molecular function</span>: dopamine beta-monooxygenase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction; histidine catabolic process; catecholamine metabolic process. 18 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000945 <newline> catecholamine metabolic process ; GO:0006584 | inferred from electronic annotation with InterPro:IPR000945 <newline> histidine catabolic process ; GO:0006548 | inferred from electronic annotation with InterPro:IPR013050","cellular_component ; GO:0005575 | no biological data available","dopamine beta-monooxygenase activity ; GO:0004500 | inferred from sequence or structural similarity with UniProtKB:P15101 <newline> copper ion binding ; GO:0005507 | inferred from electronic annotation with InterPro:IPR000323"]
["FBgn0037162","-","CG11449","This gene is referred to in FlyBase by the symbol Dmel\\CG11449 (CG11449, FBgn0037162). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:22447473..22449089. It has the cytological map location 79E4. Its molecular function is unknown. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: regulation of transcription. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","regulation of transcription ; GO:0045449 | inferred from electronic annotation with InterPro:IPR010985","-","-"]
["FBgn0037364","Rab23","Rab23","The gene Rab23 is referred to in FlyBase by the symbol Dmel\\Rab23 (CG2108, FBgn0037364). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1505776..1511148. It has the cytological map location 83B9. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: protein transport; small GTPase mediated signal transduction. 10 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579 <newline> protein transport ; GO:0015031 | inferred from electronic annotation with InterPro:IPR003579","-","GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with UniProtKB:Q9ULC3 <newline> GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225"]
["FBgn0037391","-","CG2017","This gene is referred to in FlyBase by the symbol Dmel\\CG2017 (CG2017, FBgn0037391). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1683799..1688133. It has the cytological map location 83C5-83C6. Based on sequence similarity, it is predicted to have molecular function</span>: GTP binding. The biological processes in which it is involved are not known. 9 alleles are reported. The phenotype of these alleles is annotated with: intersegmental nerve. It has 5 annotated transcripts and 5 annotated polypeptides.","-","-","GTP binding ; GO:0005525 | inferred from sequence or structural similarity with EMBL:U87965 <newline> GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR000795"]
["FBgn0037504","-","CG1142","This gene is referred to in FlyBase by the symbol Dmel\\CG1142 (CG1142, FBgn0037504). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3298176..3299496. It has the cytological map location 84D8. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0037546","-","CG7918","This gene is referred to in FlyBase by the symbol Dmel\\CG7918 (CG7918, FBgn0037546). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3885006..3912767. It has the cytological map location 84E10. Based on sequence similarity, it is predicted to have molecular function</span>: muscarinic acetylcholine receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: muscarinic acetylcholine receptor signaling pathway. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","muscarinic acetylcholine receptor signaling pathway ; GO:0007213 | inferred from sequence or structural similarity with mAcR-60C","integral to membrane ; GO:0016021 | inferred from sequence or structural similarity with mAcR-60C","muscarinic acetylcholine receptor activity ; GO:0004981 | inferred from sequence or structural similarity with mAcR-60C"]
["FBgn0037640","-","CG9731","This gene is referred to in FlyBase by the symbol Dmel\\CG9731 (CG9731, FBgn0037640). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4687716..4688504. It has the cytological map location 85B3. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0037659","-","CG11033","This gene is referred to in FlyBase by the symbol Dmel\\CG11033 (CG11033, FBgn0037659). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4878240..4888967. It has the cytological map location 85C3-85C4. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: DNA binding; zinc ion binding. The biological processes in which it is involved are not known. 30 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002857 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR002857"]
["FBgn0037719","bocksbeutel","bocksbeutel","The gene bocksbeutel is referred to in FlyBase by the symbol Dmel\\bocksbeutel (CG9424, FBgn0037719). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5415190..5416709. It has the cytological map location 85D27. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","nuclear envelope ; GO:0005635 | inferred from electronic annotation with InterPro:IPR003887","-"]
["FBgn0037753","-","CG12947","This gene is referred to in FlyBase by the symbol Dmel\\CG12947 (CG12947, FBgn0037753). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5605786..5608779. It has the cytological map location 85E8. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","-","-"]
["FBgn0037944","-","CG6923","This gene is referred to in FlyBase by the symbol Dmel\\CG6923 (CG6923, FBgn0037944). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7570204..7575186. It has the cytological map location 86E17. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; zinc ion binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","-","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR001841 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841"]
["FBgn0038166","-","CG9588","This gene is referred to in FlyBase by the symbol Dmel\\CG9588 (CG9588, FBgn0038166). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:9500814..9502398. It has the cytological map location 87F7. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: response to DNA damage stimulus. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","proteolysis ; GO:0006508 | inferred from sequence or structural similarity with NCBI_gi:4506235 <newline> response to DNA damage stimulus ; GO:0006974 | inferred from mutant phenotype","proteasome regulatory particle ; GO:0005838 | inferred from sequence or structural similarity with NCBI_gi:4506235","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR001478"]
["FBgn0038188","Arginine methyltransferase 9","Art9","The gene Arginine methyltransferase 9 is referred to in FlyBase by the symbol Dmel\\Art9 (CG9929, FBgn0038188). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:9767271..9769124. It has the cytological map location 88A2. Based on sequence similarity, it is predicted to have molecular function</span>: protein-arginine N-methyltransferase activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","protein-arginine N-methyltransferase activity ; GO:0016274 | inferred from sequence or structural similarity with SGD_LOCUS:HMT1; SGD:S0000238"]
["FBgn0038351","-","CG5302","This gene is referred to in FlyBase by the symbol Dmel\\CG5302 (CG5302, FBgn0038351). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11458605..11464977. It has the cytological map location 89A1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: serine-type endopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254","-","serine-type endopeptidase activity ; GO:0004252 | NOT non-traceable author statement <newline> serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254"]
["FBgn0038826","-","CG17838","This gene is referred to in FlyBase by the symbol Dmel\\CG17838 (CG17838, FBgn0038826). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16582451..16631963. It has the cytological map location 92F12-93A1. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. It is reported to be involved in the biological process</span>: nuclear mRNA splicing, via spliceosome. 22 alleles are reported. No phenotypic data is available. It has 8 annotated transcripts and 8 annotated polypeptides.","nuclear mRNA splicing, via spliceosome ; GO:0000398 | inferred by curator from GO:0071011","heterogeneous nuclear ribonucleoprotein complex ; GO:0030530 | inferred from sequence or structural similarity with NCBI_gi:5031755 <newline> precatalytic spliceosome ; GO:0071011 | inferred from direct assay","mRNA binding ; GO:0003729 | inferred from sequence or structural similarity <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR000504 <newline> nucleotide binding ; GO:0000166 | inferred from electronic annotation with InterPro:IPR012677"]
["FBgn0038829","-","CG17271","This gene is referred to in FlyBase by the symbol Dmel\\CG17271 (CG17271, FBgn0038829). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16644849..16647587. It has the cytological map location 93A1. Based on sequence similarity, it is predicted to have molecular function</span>: calcium ion binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","-","calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with InterPro:IPR002048"]
["FBgn0038919","-","CG17843","This gene is referred to in FlyBase by the symbol Dmel\\CG17843 (CG17843, FBgn0038919). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17739471..17741268. It has the cytological map location 93F14. Based on sequence similarity, it is predicted to have molecular function</span>: flavin-linked sulfhydryl oxidase activity; oxidoreductase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction; cell redox homeostasis. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006863, InterPro:IPR017905 <newline> cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766, InterPro:IPR017936","-","oxidoreductase activity ; GO:0016491 | inferred from sequence or structural similarity <newline> flavin-linked sulfhydryl oxidase activity ; GO:0016971 | inferred from sequence or structural similarity with HGNC_gene:QSOX1; HGNC:9756; OMIM:603120"]
["FBgn0039155","kal-1","kal-1","The gene kal-1 is referred to in FlyBase by the symbol Dmel\\kal-1 (CG6173, FBgn0039155). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19967117..19973212. It has the cytological map location 95E1-95E5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: peptidase inhibitor activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","proteinaceous extracellular matrix ; GO:0005578 | inferred from sequence or structural similarity <newline> extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR008197","peptidase inhibitor activity ; GO:0030414 | inferred from electronic annotation with InterPro:IPR008197"]
["FBgn0039167","-","CG17786","This gene is referred to in FlyBase by the symbol Dmel\\CG17786 (CG17786, FBgn0039167). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:20040345..20044438. It has the cytological map location 95F2. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0039381","-","CG17370","This gene is referred to in FlyBase by the symbol Dmel\\CG17370 (CG17370, FBgn0039381). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21707707..21713286. It has the cytological map location 96F5-96F6. There is experimental evidence that it has the molecular function</span>: aspartic endopeptidase activity, intramembrane cleaving. There is experimental evidence that it is involved in the biological process</span>: membrane protein proteolysis. 9 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides.","membrane protein proteolysis ; GO:0033619 | inferred from direct assay","integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR006639, InterPro:IPR007369","aspartic endopeptidase activity, intramembrane cleaving ; GO:0042500 | inferred from direct assay"]
["FBgn0039419","-","CG12290","This gene is referred to in FlyBase by the symbol Dmel\\CG12290 (CG12290, FBgn0039419). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:22055974..22059051. It has the cytological map location 97A6. Based on sequence similarity, it is predicted to have molecular function</span>: G-protein coupled receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: G-protein coupled receptor protein signaling pathway. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","G-protein coupled receptor protein signaling pathway ; GO:0007186 | inferred from sequence or structural similarity <newline> G-protein coupled receptor protein signaling pathway ; GO:0007186 | inferred from electronic annotation with InterPro:IPR000276","integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000276","G-protein coupled receptor activity ; GO:0004930 | inferred from sequence or structural similarity"]
["FBgn0039518","-","CG13978","This gene is referred to in FlyBase by the symbol Dmel\\CG13978 (CG13978, FBgn0039518). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:23289911..23292725. It has the cytological map location 98A1-98A2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: transferase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: GPI anchor biosynthetic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","GPI anchor biosynthetic process ; GO:0006506 | inferred from electronic annotation with InterPro:IPR007070, InterPro:IPR017852","endoplasmic reticulum membrane ; GO:0005789 | inferred from electronic annotation with InterPro:IPR007070, InterPro:IPR017852","transferase activity ; GO:0016740 | inferred from electronic annotation with InterPro:IPR007070, InterPro:IPR017852"]
["FBgn0039633","-","CG11873","This gene is referred to in FlyBase by the symbol Dmel\\CG11873 (CG11873, FBgn0039633). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:24890065..24932424. It has the cytological map location 98F6-98F10. Its molecular function is unknown. The biological processes in which it is involved are not known. 19 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0039669","-","CG2014","This gene is referred to in FlyBase by the symbol Dmel\\CG2014 (CG2014, FBgn0039669). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25341535..25342249. It has the cytological map location 99B2. Based on sequence similarity, it is predicted to have molecular function</span>: NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, NADH to ubiquinone. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:O75251","mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:P42026 <newline> mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:O75251","NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from sequence or structural similarity with UniProtKB:P42026 <newline> NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:P42026 <newline> NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:O75251 <newline> 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR006137, InterPro:IPR006138, InterPro:IPR014406 <newline> quinone binding ; GO:0048038 | inferred from electronic annotation with InterPro:IPR006137, InterPro:IPR006138"]
["FBgn0039864","-","CG11550","This gene is referred to in FlyBase by the symbol Dmel\\CG11550 (CG11550, FBgn0039864). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27503949..27505602. It has the cytological map location 100D1. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0039945","-","CG17159","This gene is referred to in FlyBase by the symbol Dmel\\CG17159 (CG17159, FBgn0039945). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is XHet:63778..75553. It has the cytological map location 20E. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0039958","-","CG12567","This gene is referred to in FlyBase by the symbol Dmel\\CG12567 (CG12567, FBgn0039958). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2LHet:19633..32995. Based on sequence similarity, it is predicted to have molecular function</span>: thiamin diphosphokinase activity. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides.","-","-","thiamin diphosphokinase activity ; GO:0004788 | inferred from sequence or structural similarity with UniProtKB:P41888 <newline> hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR000086, InterPro:IPR015797"]
["FBgn0040396","-","CG3939","This gene is referred to in FlyBase by the symbol Dmel\\CG3939 (CG3939, FBgn0040396). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3069152..3070257. It has the cytological map location 3C9. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0040496","-","CG17104","This gene is referred to in FlyBase by the symbol Dmel\\CG17104 (CG17104, FBgn0040496). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:10677370..10679525. It has the cytological map location 32A3. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0040752","Prosap","Prosap","The gene Prosap is referred to in FlyBase by the symbol Dmel\\Prosap (CG30483, FBgn0040752). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9948984..10028403. It has the cytological map location 50D3-50E1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding. The biological processes in which it is involved are not known. 17 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR001478"]
["FBgn0042094","Adenylate kinase-3","Adk3","The gene Adenylate kinase-3 is referred to in FlyBase by the symbol Dmel\\Adk3 (CG6612, FBgn0042094). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:6713288..6715310. It has the cytological map location 86C7. Based on sequence similarity, it is predicted to have molecular function</span>: nucleoside triphosphate adenylate kinase activity; adenylate kinase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: ADP biosynthetic process. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","ADP biosynthetic process ; GO:0006172 | inferred from sequence or structural similarity with UniProtKB:Q9UIJ7","mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:Q9UIJ7","adenylate kinase activity ; GO:0004017 | non-traceable author statement <newline> adenylate kinase activity ; GO:0004017 | inferred from sequence or structural similarity with EMBL:AB020203; protein_id:BAA77360.1 <newline> nucleoside triphosphate adenylate kinase activity ; GO:0046899 | inferred from sequence or structural similarity with UniProtKB:P54819 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000850, InterPro:IPR006259"]
["FBgn0044823","Spec2","Spec2","The gene Spec2 is referred to in FlyBase by the symbol Dmel\\Spec2 (CG14672, FBgn0044823). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1442368..1449844. It has the cytological map location 83B6. Its molecular function is unknown. The biological processes in which it is involved are not known. 19 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0050421","-","CG30421","This gene is referred to in FlyBase by the symbol Dmel\\CG30421 (CG30421, FBgn0050421). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20631335..20644501. It has the cytological map location 60D16-60E1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: ubiquitin thiolesterase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: ubiquitin-dependent protein catabolic process. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR001394, InterPro:IPR018200","-","ubiquitin thiolesterase activity ; GO:0004221 | inferred from electronic annotation with InterPro:IPR001394, InterPro:IPR018200"]
["FBgn0050447","-","CG30447","This gene is referred to in FlyBase by the symbol Dmel\\CG30447 (CG30447, FBgn0050447). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15834726..15835588. It has the cytological map location 56E5. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0051028","-","CG31028","This gene is referred to in FlyBase by the symbol Dmel\\CG31028 (CG31028, FBgn0051028). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25992353..25996925. It has the cytological map location 99E1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: metal ion binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction; superoxide metabolic process. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR001424 <newline> superoxide metabolic process ; GO:0006801 | inferred from electronic annotation with InterPro:IPR001424","-","metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001424"]
["FBgn0051320","-","CG31320","This gene is referred to in FlyBase by the symbol Dmel\\CG31320 (CG31320, FBgn0051320). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:10184078..10187461. It has the cytological map location 88B6. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR011989, InterPro:IPR016024"]
["FBgn0051473","-","CG31473","This gene is referred to in FlyBase by the symbol Dmel\\CG31473 (CG31473, FBgn0051473). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3637536..3638731. It has the cytological map location 84E1. Based on sequence similarity, it is predicted to have molecular function</span>: pyridoxamine-phosphate oxidase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: pyridoxine biosynthetic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","pyridoxine biosynthetic process ; GO:0008615 | inferred from sequence or structural similarity with EMBL:U91561 <newline> oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000659","-","pyridoxamine-phosphate oxidase activity ; GO:0004733 | inferred from sequence or structural similarity with EMBL:U91561 <newline> FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR011576, InterPro:IPR012349"]
["FBgn0051612","-","CG31612","This gene is referred to in FlyBase by the symbol Dmel\\CG31612 (CG31612, FBgn0051612). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:21762314..21795445. It has the cytological map location 40A2-40A3. Based on sequence similarity, it is predicted to have molecular function</span>: nucleic acid binding. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","nucleus ; GO:0005634 | inferred from sequence or structural similarity with InterPro:IPR007087 <newline> lipid particle ; GO:0005811 | inferred from direct assay","nucleic acid binding ; GO:0003676 | inferred from sequence or structural similarity with InterPro:IPR007087 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
["FBgn0051721","Trim9","Trim9","The gene Trim9 is referred to in FlyBase by the symbol Dmel\\Trim9 (CG31721, FBgn0051721). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:10544881..10627374. It has the cytological map location 31F5-32A2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; zinc ion binding. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR000315, InterPro:IPR003649","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR001841 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR000315, InterPro:IPR001841"]
["FBgn0051840","-","CG31840","This gene is referred to in FlyBase by the symbol Dmel\\CG31840 (FBgn0051840).The gene previously had a gene model which is not supported by current evidence. It is a protein_coding_gene from Drosophila melanogaster. It has not been localized to the genome sequence. It has the cytological map location 34F1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: metallopeptidase activity; zinc ion binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis. 2 alleles are reported. No phenotypic data is available..","proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR006025","cellular_component ; GO:0005575 | no biological data available","metallopeptidase activity ; GO:0008237 | inferred from electronic annotation with InterPro:IPR006025 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR006025"]
["FBgn0052118","-","CG32118","This gene is referred to in FlyBase by the symbol Dmel\\CG32118 (FBgn0052118).The gene previously had a gene model which is not supported by current evidence. It is a protein_coding_gene from Drosophila melanogaster. It has not been localized to the genome sequence. It has the cytological map location 70A1. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available..","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0052252","-","CG32252","This gene is referred to in FlyBase by the symbol Dmel\\CG32252 (CG32252, FBgn0052252). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4221689..4222734. It has the cytological map location 64A10. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0052264","-","CG32264","This gene is referred to in FlyBase by the symbol Dmel\\CG32264 (CG32264, FBgn0052264). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:3717217..3803454. It has the cytological map location 63E8-63F1. Its molecular function is unknown. The biological processes in which it is involved are not known. 17 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides.","-","-","-"]
["FBgn0052392","-","CG32392","This gene is referred to in FlyBase by the symbol Dmel\\CG32392 (CG32392, FBgn0052392). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:6749723..6756346. It has the cytological map location 65C4. Based on sequence similarity, it is predicted to have molecular function</span>: microtubule binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: microtubule-based process. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","microtubule-based process ; GO:0007017 | inferred from sequence or structural similarity","microtubule associated complex ; GO:0005875 | inferred from sequence or structural similarity","microtubule binding ; GO:0008017 | inferred from sequence or structural similarity"]
["FBgn0052529","-","CG32529","This gene is referred to in FlyBase by the symbol Dmel\\CG32529 (CG32529, FBgn0052529). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:19762443..19800720. It has the cytological map location 18F4-19A2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: DNA binding. The biological processes in which it is involved are not known. 28 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","-","-","DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001025"]
["FBgn0052556","-","CG32556","This gene is referred to in FlyBase by the symbol Dmel\\CG32556 (CG32556, FBgn0052556). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:17566483..17592559. It has the cytological map location 16B12-16C1. Its molecular function is unknown. The biological processes in which it is involved are not known. 11 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","-","-"]
["FBgn0052676","-","CG32676","This gene is referred to in FlyBase by the symbol Dmel\\CG32676 (CG32676, FBgn0052676). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:10607151..10638938. It has the cytological map location 9E1-9E2. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: cellular process. 34 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","cellular process ; GO:0009987 | inferred from mutant phenotype","-","-"]
["FBgn0053111","-","CG33111","This gene is referred to in FlyBase by the symbol Dmel\\CG33111 (CG33111, FBgn0053111). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19627422..19644954. It has the cytological map location 95B7-95C1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: transition metal ion binding; oxidoreductase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction. 6 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR009078","-","oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR009078 <newline> transition metal ion binding ; GO:0046914 | inferred from electronic annotation with InterPro:IPR009078"]
["FBgn0053291","-","CG33291","This gene is referred to in FlyBase by the symbol Dmel\\CG33291 (CG33291, FBgn0053291). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:21638060..21659405. It has the cytological map location 78E2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; DNA binding. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR009072 <newline> protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR000210, InterPro:IPR011333, InterPro:IPR013069"]
["FBgn0053647","-","CG33647","This gene is referred to in FlyBase by the symbol Dmel\\CG33647 (CG33647, FBgn0053647). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19229460..19230157. It has the cytological map location 76A3. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0053648","-","CG33648","This gene is referred to in FlyBase by the symbol Dmel\\CG33648 (CG33648, FBgn0053648). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:14524926..14525625. It has the cytological map location 35B2. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0053796","-","CG33796","This gene is referred to in FlyBase by the symbol Dmel\\CG33796 (CG33796, FBgn0053796). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:16162555..16163206. It has the cytological map location 72D9. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0054006","-","CG34006","This gene is referred to in FlyBase by the symbol Dmel\\CG34006 (CG34006, FBgn0054006). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:23042671..23043696. It has the cytological map location 97E8-97E9. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0054046","-","CG34046","This gene is referred to in FlyBase by the symbol Dmel\\CG34046 (CG34046, FBgn0054046). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27534987..27535336. It has the cytological map location 100D1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0054050","-","CG34050","This gene is referred to in FlyBase by the symbol Dmel\\CG34050 (CG34050, FBgn0054050). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:10937556..10938200. It has the cytological map location 67F1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0063261","-","CG31275","This gene is referred to in FlyBase by the symbol Dmel\\CG31275 (CG31275, FBgn0063261). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12576454..12577111. It has the cytological map location 89E1. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled. It is reported to be involved in the biological process</span>: microtubule-based movement. One allele is reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","microtubule-based movement ; GO:0007018 | non-traceable author statement","dynein complex ; GO:0030286 | inferred from sequence or structural similarity <newline> cytoskeleton ; GO:0005856 | non-traceable author statement","ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity"]
["FBgn0067783","alternative testis transcripts open reading frame A","att-ORFA","The gene alternative testis transcripts open reading frame A is referred to in FlyBase by the symbol Dmel\\att-ORFA (CG4241, FBgn0067783). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16378111..16383403. It has the cytological map location 92F1. Based on sequence similarity, it is predicted to have molecular function</span>: transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.","transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001993, InterPro:IPR002067","mitochondrial envelope ; GO:0005740 | inferred from sequence or structural similarity with UniProtKB:P38702 <newline> mitochondrial envelope ; GO:0005740 | inferred from sequence or structural similarity <newline> mitochondrial inner membrane ; GO:0005743 | inferred from electronic annotation with InterPro:IPR002067, InterPro:IPR002167","transmembrane transporter activity ; GO:0022857 | inferred from sequence or structural similarity with UniProtKB:P38702 <newline> transmembrane transporter activity ; GO:0022857 | inferred from sequence or structural similarity <newline> binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR001993, InterPro:IPR002067, InterPro:IPR002167"]
["FBgn0083940","-","CG34104","This gene is referred to in FlyBase by the symbol Dmel\\CG34104 (CG34104, FBgn0083940). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:9980566..10042911. It has the cytological map location 9B1-9B2. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: small GTPase mediated signal transduction. 12 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","small GTPase mediated signal transduction ; GO:0007264 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003578","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR003578","GTPase activity ; GO:0003924 | inferred from sequence or structural similarity with SGD_LOCUS:CDC42; SGD:S0004219 <newline> GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003578, InterPro:IPR005225"]
["FBgn0083951","-","CG34115","This gene is referred to in FlyBase by the symbol Dmel\\CG34115 (CG34115, FBgn0083951). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:16863005..16864439. It has the cytological map location 57B5. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0083978","-","CG17672","This gene is referred to in FlyBase by the symbol Dmel\\CG17672 (CG17672, FBgn0083978). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:13022064..13029537. It has the cytological map location 69F6. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: structural constituent of ribosome. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: translation. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","translation ; GO:0006412 | inferred from electronic annotation with InterPro:IPR000530","ribosome ; GO:0005840 | inferred from electronic annotation with InterPro:IPR000530","structural constituent of ribosome ; GO:0003735 | inferred from electronic annotation with InterPro:IPR000530"]
["FBgn0085201","-","CG34172","This gene is referred to in FlyBase by the symbol Dmel\\CG34172 (CG34172, FBgn0085201). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:2192525..2193010. It has the cytological map location 22D1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0085318","-","CG34289","This gene is referred to in FlyBase by the symbol Dmel\\CG34289 (CG34289, FBgn0085318). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19332631..19334851. It has the cytological map location 94F6. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has 2 annotated transcripts and 2 annotated polypeptides.","-","-","-"]
["FBgn0085397","Fish-lips","Fili","The gene Fish-lips is referred to in FlyBase by the symbol Dmel\\Fili (CG34368, FBgn0085397). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:17759537..17833769. It has the cytological map location 58A3-58A4. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding. The biological processes in which it is involved are not known. 12 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.","-","-","protein binding ; GO:0005515 | inferred from electronic annotation with InterPro:IPR001611"]
["FBgn0085489","-","CG34460","This gene is referred to in FlyBase by the symbol Dmel\\CG34460 (CG34460, FBgn0085489). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12714402..12715310. It has the cytological map location 53D11. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0250818","-","CG34360","This gene is referred to in FlyBase by the symbol Dmel\\CG34360 (CG34360, FBgn0250818). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5700403..5814598. It has the cytological map location 85F1-85F4. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. The biological processes in which it is involved are not known. 21 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides.","biological_process ; GO:0008150 | no biological data available","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
["FBgn0259699","-","CG42353","This gene is referred to in FlyBase by the symbol Dmel\\CG42353 (CG42353, FBgn0259699). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15987103..15998945. It has the cytological map location 14A9. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.","-","-","-"]
["FBgn0260966","sickie","sick","The gene sickie is referred to in FlyBase by the symbol Dmel\\sick (CG42589, FBgn0260966). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:19856184..19957767. It has the cytological map location 38A8. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: nucleoside-triphosphatase activity; ATP binding. There is experimental evidence that it is involved in the biological process</span>: defense response to Gram-negative bacterium. 31 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides.","defense response to Gram-negative bacterium ; GO:0050829 | inferred from mutant phenotype","cellular_component ; GO:0005575 | no biological data available","ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR003959 <newline> nucleoside-triphosphatase activity ; GO:0017111 | inferred from electronic annotation with InterPro:IPR003593"]
["FBgn0084061","-","Dmir\\CG33291","This gene is referred to in FlyBase by the symbol Dmir\\CG33291 (FBgn0084061). It is a gene from Drosophila miranda. It has not been localized to the genome sequence. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: DNA binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: nucleosome assembly. No alleles are reported..","nucleosome assembly ; GO:0006334 | inferred from electronic annotation with InterPro:IPR002119","nucleosome ; GO:0000786 | inferred from electronic annotation with InterPro:IPR002119 <newline> nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR002119","DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR002119, InterPro:IPR009072"]
["FBgn0084101","-","Dmir\\CG9674","This gene is referred to in FlyBase by the symbol Dmir\\CG9674 (FBgn0084101). It is a gene from Drosophila miranda. It has not been localized to the genome sequence. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: iron-sulfur cluster binding; oxidoreductase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction. No alleles are reported..","oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR002489, InterPro:IPR009051","-","iron-sulfur cluster binding ; GO:0051536 | inferred from electronic annotation with InterPro:IPR009051, InterPro:IPR012285 <newline> oxidoreductase activity ; GO:0016491 | inferred from electronic annotation with InterPro:IPR002489, InterPro:IPR009051, InterPro:IPR012285"]
["FBgn0084143","-","Dmir\\CG8034","This gene is referred to in FlyBase by the symbol Dmir\\CG8034 (FBgn0084143). It is a gene from Drosophila miranda. It has not been localized to the genome sequence. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported..","-","-","-"]
["FBgn0084474","-","Dmir\\CG12734","This gene is referred to in FlyBase by the symbol Dmir\\CG12734 (FBgn0084474). It is a gene from Drosophila miranda. It has not been localized to the genome sequence. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported..","-","-","-"]
["FBgn0084634","-","Dmir\\CG13900","This gene is referred to in FlyBase by the symbol Dmir\\CG13900 (FBgn0084634). It is a gene from Drosophila miranda. It has not been localized to the genome sequence. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: nucleic acid binding. The biological processes in which it is involved are not known. No alleles are reported..","-","nucleus ; GO:0005634 | inferred from electronic annotation with InterPro:IPR004871","nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR004871"]
["FBgn0084903","-","Dmir\\CG9203","This gene is referred to in FlyBase by the symbol Dmir\\CG9203 (FBgn0084903). It is a gene from Drosophila miranda. It has not been localized to the genome sequence. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported..","-","-","-"]
["FBgn0064422","-","Dpse\\GA22108","This gene is referred to in FlyBase by the symbol Dpse\\GA22108 (GA22108, FBgn0064422). It is a protein_coding_gene from Drosophila pseudoobscura pseudoobscura. Its sequence location is 3:2434694..2435382. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding; nucleic acid binding. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","-","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087"]
["FBgn0064435","-","Dpse\\GA15834","This gene is referred to in FlyBase by the symbol Dpse\\GA15834 (GA15834, FBgn0064435). It is a protein_coding_gene from Drosophila pseudoobscura pseudoobscura. Its sequence location is 3:10881536..10893897. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: ubiquitin thiolesterase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: ubiquitin-dependent protein catabolic process. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR001394, InterPro:IPR018200","-","ubiquitin thiolesterase activity ; GO:0004221 | inferred from electronic annotation with InterPro:IPR001394, InterPro:IPR018200"]
["FBgn0075210","-","Dpse\\GA15185","This gene is referred to in FlyBase by the symbol Dpse\\GA15185 (GA15185, FBgn0075210). It is a protein_coding_gene from Drosophila pseudoobscura pseudoobscura. Its sequence location is 2:2205034..2205669. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: 4 iron, 4 sulfur cluster binding; quinone binding; NADH dehydrogenase (ubiquinone) activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006137, InterPro:IPR006138, InterPro:IPR014406","-","NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from electronic annotation with InterPro:IPR006137, InterPro:IPR006138 <newline> 4 iron, 4 sulfur cluster binding ; GO:0051539 | inferred from electronic annotation with InterPro:IPR006137, InterPro:IPR006138, InterPro:IPR014406 <newline> quinone binding ; GO:0048038 | inferred from electronic annotation with InterPro:IPR006137, InterPro:IPR006138"]
["FBgn0079079","-","Dpse\\GA19081","This gene is referred to in FlyBase by the symbol Dpse\\GA19081 (GA19081, FBgn0079079). It is a protein_coding_gene from Drosophila pseudoobscura pseudoobscura. Its sequence location is XR_group6:1901720..1903666. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: oxidoreductase activity, acting on the CH-CH group of donors; electron carrier activity; FAD binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: electron transport chain; tricarboxylic acid cycle. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","tricarboxylic acid cycle ; GO:0006099 | inferred from electronic annotation with InterPro:IPR011281 <newline> electron transport chain ; GO:0022900 | inferred from electronic annotation with InterPro:IPR014006","-","oxidoreductase activity, acting on the CH-CH group of donors ; GO:0016627 | inferred from electronic annotation with InterPro:IPR011281, InterPro:IPR014006 <newline> electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR003953 <newline> FAD binding ; GO:0050660 | inferred from electronic annotation with InterPro:IPR011281, InterPro:IPR014006"]
["FBgn0081578","-","Dpse\\GA21592","This gene is referred to in FlyBase by the symbol Dpse\\GA21592 (GA21592, FBgn0081578). It is a protein_coding_gene from Drosophila pseudoobscura pseudoobscura. Its sequence location is Unknown_group_529:2376..3038. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0246094","-","Dpse\\GA24708","This gene is referred to in FlyBase by the symbol Dpse\\GA24708 (GA24708, FBgn0246094). It is a protein_coding_gene from Drosophila pseudoobscura pseudoobscura. Its sequence location is 3:4313452..4314093. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0261212","-","Dsec\\CG3011","This gene is referred to in FlyBase by the symbol Dsec\\CG3011 (FBgn0261212). It is a gene from Drosophila sechellia. It has not been localized to the genome sequence. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported..","-","-","-"]
["FBgn0045604","-","Dsim\\GD12810","This gene is referred to in FlyBase by the symbol Dsim\\GD12810 (GD12810, FBgn0045604). It is a protein_coding_gene from Drosophila simulans. Its sequence location is 3L:10703560..10704591. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: peptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR007484","-","peptidase activity ; GO:0008233 | inferred from electronic annotation with InterPro:IPR007484"]
["FBgn0045627","-","Dsim\\GD20911","This gene is referred to in FlyBase by the symbol Dsim\\GD20911 (GD20911, FBgn0045627). It is a protein_coding_gene from Drosophila simulans. Its sequence location is 3R:17550637..17552295. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: thiol oxidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction; cell redox homeostasis. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","oxidation reduction ; GO:0055114 | inferred from electronic annotation with InterPro:IPR006863, InterPro:IPR017905 <newline> cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766, InterPro:IPR017936","-","thiol oxidase activity ; GO:0016972 | inferred from electronic annotation with InterPro:IPR006863, InterPro:IPR017905"]
["FBgn0045658","-","Dsim\\CG10741","This gene is referred to in FlyBase by the symbol Dsim\\CG10741 (FBgn0045658). It is a gene from Drosophila simulans. It has not been localized to the genome sequence. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported..","-","-","-"]
["FBgn0083450","-","Dsim\\CG32541","This gene is referred to in FlyBase by the symbol Dsim\\CG32541 (FBgn0083450). It is a gene from Drosophila simulans. It has not been localized to the genome sequence. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported..","-","-","-"]
["FBgn0260199","-","Dsim\\CG4766","This gene is referred to in FlyBase by the symbol Dsim\\CG4766 (FBgn0260199). It is a gene from Drosophila simulans. It has not been localized to the genome sequence. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported..","-","-","-"]
["FBgn0064290","-","Dwil\\GK21665","This gene is referred to in FlyBase by the symbol Dwil\\GK21665 (GK21665, FBgn0064290). It is a protein_coding_gene from Drosophila willistoni. Its sequence location is scf2_1100000004513:50141..68879. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: ubiquitin thiolesterase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: ubiquitin-dependent protein catabolic process. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","ubiquitin-dependent protein catabolic process ; GO:0006511 | inferred from electronic annotation with InterPro:IPR001394, InterPro:IPR018200","-","ubiquitin thiolesterase activity ; GO:0004221 | inferred from electronic annotation with InterPro:IPR001394, InterPro:IPR018200"]
["FBgn0068321","-","Dyak\\GE16296","This gene is referred to in FlyBase by the symbol Dyak\\GE16296 (GE16296, FBgn0068321). It is a protein_coding_gene from Drosophila yakuba. Its sequence location is X:5297982..5298682. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0068347","-","Dyak\\GE16954","This gene is referred to in FlyBase by the symbol Dyak\\GE16954 (GE16954, FBgn0068347). It is a protein_coding_gene from Drosophila yakuba. Its sequence location is X:6140060..6153444. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0068415","-","Dyak\\GE20625","This gene is referred to in FlyBase by the symbol Dyak\\GE20625 (GE20625, FBgn0068415). It is a protein_coding_gene from Drosophila yakuba. Its sequence location is 3L:4873300..4873946. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0068446","-","Dyak\\GE15338","This gene is referred to in FlyBase by the symbol Dyak\\GE15338 (GE15338, FBgn0068446). It is a protein_coding_gene from Drosophila yakuba. Its sequence location is X:19833734..19834594. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0068494","-","Dyak\\GE20094","This gene is referred to in FlyBase by the symbol Dyak\\GE20094 (GE20094, FBgn0068494). It is a protein_coding_gene from Drosophila yakuba. Its sequence location is 3L:12893560..12900285. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: substrate-specific transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR003663, InterPro:IPR005828, InterPro:IPR005829","integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR005828","substrate-specific transmembrane transporter activity ; GO:0022891 | inferred from electronic annotation with InterPro:IPR003663"]
["FBgn0068498","-","Dyak\\GE14096","This gene is referred to in FlyBase by the symbol Dyak\\GE14096 (GE14096, FBgn0068498). It is a protein_coding_gene from Drosophila yakuba. Its sequence location is 2R:16946155..16946766. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0237542","-","Dyak\\GE20221","This gene is referred to in FlyBase by the symbol Dyak\\GE20221 (GE20221, FBgn0237542). It is a protein_coding_gene from Drosophila yakuba. Its sequence location is 3L:11349624..11350658. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide.","-","-","-"]
["FBgn0086200","-","CG42490","This gene is referred to in FlyBase by the symbol Dmel\\CG42490 (FBgn0086200). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 2L:18665232..18666863.","-","-","-"]
["FBgn0011283","Pheromone-binding protein-related protein 5","Pbprp5","The gene Pheromone-binding protein-related protein 5 is referred to in FlyBase by the symbol Dmel\\Pbprp5 (CG6641, FBgn0011283). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: pheromone binding; odorant binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: sensory perception of chemical stimulus. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Insect pheromone/odorant binding protein PhBP; Pheromone/general odorant binding protein, PBP/GOBP; Pheromone/general odorant binding protein, PBP/GOBP, domain. Gene sequence location is 2L:7496785..7497360.","sensory perception of chemical stimulus ; GO:0007606 | inferred from sequence alignment with UniProtKB:P34174 <newline> transport ; GO:0006810 | inferred from electronic annotation with InterPro:IPR006170","extracellular region ; GO:0005576 | non-traceable author statement","pheromone binding ; GO:0005550 | inferred from sequence or structural similarity <newline> phenylalkylamine binding ; GO:0008145 | non-traceable author statement <newline> pheromone binding ; GO:0005550 | non-traceable author statement <newline> odorant binding ; GO:0005549 | inferred from sequence alignment with UniProtKB:P34174 <newline> odorant binding ; GO:0005549 | inferred from electronic annotation with InterPro:IPR006170"]
["FBgn0037720","-","CG8312","This gene is referred to in FlyBase by the symbol Dmel\\CG8312 (FBgn0037720). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Pleckstrin homology-type. Gene sequence location is 3R:5417033..5450798.","-","-","-"]
["FBgn0034186","-","CG8950","This gene is referred to in FlyBase by the symbol Dmel\\CG8950 (FBgn0034186). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Tetratricopeptide TPR-1; Tetratricopeptide repeat; Tetratricopeptide repeat-containing; Tetratricopeptide-like helical. Gene sequence location is 2R:12947368..12950139.","-","-","binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR011990"]
["FBgn0027088","Glycyl-tRNA synthetase","Aats-gly","The gene Glycyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\\Aats-gly (CG6778, FBgn0027088). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: glycine-tRNA ligase activity. It is reported to be involved in the biological process</span>: glycyl-tRNA aminoacylation. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Aminoacyl-tRNA synthetase, class II; Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; Glycyl-tRNA synthetase, alpha2 dimer; S15/NS1, RNA-binding; WHEP-TRS. Gene sequence location is 3L:15088256..15090790.","glycyl-tRNA aminoacylation ; GO:0006426 | non-traceable author statement <newline> glycyl-tRNA aminoacylation ; GO:0006426 | inferred from electronic annotation with InterPro:IPR002315","cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR002314, InterPro:IPR002315, InterPro:IPR006195","glycine-tRNA ligase activity ; GO:0004820 | inferred from sequence or structural similarity with UniProtKB:P41250 AND non-traceable author statement <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000738, InterPro:IPR002314, InterPro:IPR002315, InterPro:IPR004154, InterPro:IPR006195"]
["FBgn0259700","-","CG42354","This gene is referred to in FlyBase by the symbol Dmel\\CG42354 (FBgn0259700). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Gene sequence location is X:15987090..15998945.","-","-","-"]
["FBgn0034501","-","CG13868","This gene is referred to in FlyBase by the symbol Dmel\\CG13868 (FBgn0034501). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Gene sequence location is 2R:16196217..16204415.","-","-","-"]
["FBgn0034322","-","CG18536","This gene is referred to in FlyBase by the symbol Dmel\\CG18536 (FBgn0034322). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Protein of unknown function DUF1091. Gene sequence location is 2R:14176597..14183163.","-","-","-"]
["FBgn0031590","-","CG3702","This gene is referred to in FlyBase by the symbol Dmel\\CG3702 (FBgn0031590). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Cleft lip and palate transmembrane 1. Gene sequence location is 2L:4224650..4227097.","-","-","-"]
["FBgn0039219","-","CG13630","This gene is referred to in FlyBase by the symbol Dmel\\CG13630 (FBgn0039219). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: aminopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis; cellular process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase M24, methionine aminopeptidase; Peptidase M24, structural domain; Peptidase M24A, methionine aminopeptidase, subfamily 1. Gene sequence location is 3R:20543657..20545084.","proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001714, InterPro:IPR002467 <newline> cellular process ; GO:0009987 | inferred from electronic annotation with InterPro:IPR000994","-","aminopeptidase activity ; GO:0004177 | inferred from sequence or structural similarity with SGD_LOCUS:MAP1; SGD:S0004234 <newline> metalloexopeptidase activity ; GO:0008235 | inferred from electronic annotation with InterPro:IPR001714, InterPro:IPR002467"]
["FBgn0014903","-","CG14630","This gene is referred to in FlyBase by the symbol Dmel\\CG14630 (FBgn0014903). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: gamma-butyrobetaine dioxygenase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: RNAse P, Rpr2/Rpp21 subunit; Taurine catabolism dioxygenase TauD/TfdA. Gene sequence location is X:925538..927198.","oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR003819","-","gamma-butyrobetaine dioxygenase activity ; GO:0008336 | inferred from sequence or structural similarity <newline> gamma-butyrobetaine dioxygenase activity ; GO:0008336 | inferred from sequence or structural similarity with NCBI_gi:4502369"]
["FBgn0053346","-","CG33346","This gene is referred to in FlyBase by the symbol Dmel\\CG33346 (FBgn0053346). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: metal ion binding; hydrolase activity; nucleic acid binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: DNA/RNA non-specific endonuclease; DNA/RNA non-specific endonuclease, active site; Extracellular Endonuclease, subunit A. Gene sequence location is 3R:24494955..24496174.","-","-","hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR018524, InterPro:IPR020821 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR018524, InterPro:IPR020821 <newline> metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR018524, InterPro:IPR020821"]
["FBgn0053465","-","CG33465","This gene is referred to in FlyBase by the symbol Dmel\\CG33465 (FBgn0053465). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 2R:11706619..11708600.","-","-","-"]
["FBgn0036405","-","CG6833","This gene is referred to in FlyBase by the symbol Dmel\\CG6833 (FBgn0036405). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: exonuclease activity; nucleic acid binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Exonuclease; Exonuclease, RNase T/DNA polymerase III; Ribonuclease H-like. Gene sequence location is 3L:14044311..14045569.","-","intracellular ; GO:0005622 | inferred from electronic annotation with InterPro:IPR006055","exonuclease activity ; GO:0004527 | inferred from electronic annotation with InterPro:IPR006055 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR012337"]
["FBgn0035501","-","CG1299","This gene is referred to in FlyBase by the symbol Dmel\\CG1299 (FBgn0035501). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function</span>: serine-type endopeptidase activity. It is reported to be involved in the biological process</span>: proteolysis. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Disulphide knot CLIP; Peptidase S1/S6, chymotrypsin/Hap; Peptidase S1/S6, chymotrypsin/Hap, active site; Peptidase S1A, chymotrypsin-type; Peptidase cysteine/serine, trypsin-like; Proteinase, regulatory CLIP domain. Gene sequence location is 3L:4148697..4152477.","proteolysis ; GO:0006508 | non-traceable author statement <newline> proteolysis ; GO:0006508 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR018114","-","serine-type endopeptidase activity ; GO:0004252 | non-traceable author statement <newline> serine-type endopeptidase activity ; GO:0004252 | inferred from electronic annotation with InterPro:IPR001254, InterPro:IPR001314, InterPro:IPR006604, InterPro:IPR018114"]
["FBgn0050413","-","CG30413","This gene is referred to in FlyBase by the symbol Dmel\\CG30413 (FBgn0050413). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 2R:19217066..19217593.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0051163","Shal K[+] channel interacting protein","SKIP","The gene Shal K<sup>+</sup> channel interacting protein is referred to in FlyBase by the symbol Dmel\\SKIP (CG31163, FBgn0051163). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: SH3/SH2 adaptor activity. The biological processes in which it is involved are not known. 33 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Src homology-3 domain; Sterile alpha motif domain; Sterile alpha motif homology; Sterile alpha motif, type 2; Sterile alpha motif-type; Variant SH3. Gene sequence location is 3R:17959557..18121848.","-","-","SH3/SH2 adaptor activity ; GO:0005070 | inferred from sequence or structural similarity with UniProtKB:P87378"]
["FBgn0034196","-","CG15605","This gene is referred to in FlyBase by the symbol Dmel\\CG15605 (FBgn0034196). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: RWD domain; Ubiquitin-conjugating enzyme/RWD-like. Gene sequence location is 2R:13013912..13014528.","-","-","-"]
["FBgn0035514","-","CG1332","This gene is referred to in FlyBase by the symbol Dmel\\CG1332 (FBgn0035514). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: sphingomyelin phosphodiesterase activator activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Beige/BEACH; WD40 repeat; WD40 repeat 2; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Gene sequence location is 3L:4216636..4224004.","-","-","sphingomyelin phosphodiesterase activator activity ; GO:0016230 | inferred from sequence or structural similarity with UniProtKB:O35242"]
["FBgn0043457","-","CG5180","This gene is referred to in FlyBase by the symbol Dmel\\CG5180 (FBgn0043457). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotypes of these alleles are annotated with: dorsocentral bristle; scutellar bristle. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: MADF domain. Gene sequence location is 3R:16383652..16385484.","-","-","-"]
["FBgn0036446","-","CG9384","This gene is referred to in FlyBase by the symbol Dmel\\CG9384 (FBgn0036446). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: carbohydrate metabolic process. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Glycosyl transferase, family 54. Gene sequence location is 3L:14755145..14760812.","carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR006759","membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR006759","alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity ; GO:0008454 | inferred from sequence or structural similarity with EMBL:AB000628; protein_id:BAA31162"]
["FBgn0036302","sosondowah","sowah","The gene sosondowah is referred to in FlyBase by the symbol Dmel\\sowah (CG10632, FBgn0036302). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain. Gene sequence location is 3L:12530612..12565622.","-","-","-"]
["FBgn0030266","-","CG11122","This gene is referred to in FlyBase by the symbol Dmel\\CG11122 (FBgn0030266). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Zinc finger, C2H2-like; Zinc finger, C2H2-type. Gene sequence location is X:11006428..11017631.","-","microtubule associated complex ; GO:0005875 | inferred from direct assay","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880"]
["FBgn0259734","-","CG42388","This gene is referred to in FlyBase by the symbol Dmel\\CG42388 (FBgn0259734). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Src homology-3 domain. Gene sequence location is X:8924238..8947352.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0027529","-","CG8920","This gene is referred to in FlyBase by the symbol Dmel\\CG8920 (FBgn0027529). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: nucleic acid binding. The biological processes in which it is involved are not known. 18 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Maternal tudor protein; Tudor domain. Gene sequence location is 2R:16193796..16213478.","-","-","nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002999"]
["FBgn0052102","-","CG32102","This gene is referred to in FlyBase by the symbol Dmel\\CG32102 (FBgn0052102). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 3L:12462172..12462884.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0052831","-","CG33695","This gene is referred to in FlyBase by the symbol Dmel\\CG33695 (FBgn0052831). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: DNA binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: SANT domain, DNA binding. Gene sequence location is 2L:11269727..11279847.","-","-","DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR001005"]
["FBgn0260486","-","CG42533","This gene is referred to in FlyBase by the symbol Dmel\\CG42533 (FBgn0260486). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: GTP binding; GTPase binding; guanyl-nucleotide exchange factor activity. The biological processes in which it is involved are not known. 12 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Dedicator of cytokinesis; Pleckstrin homology domain; Pleckstrin homology-type. Gene sequence location is 2L:7472505..7495618.","-","-","GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR010703 <newline> guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from electronic annotation with InterPro:IPR010703 <newline> GTPase binding ; GO:0051020 | inferred from electronic annotation with InterPro:IPR010703"]
["FBgn0243517","-","CG4567","This gene is referred to in FlyBase by the symbol Dmel\\CG4567 (FBgn0243517). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: translation elongation factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translational elongation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Elongation factor G/III/V; Protein synthesis factor, GTP-binding; Ribosomal protein S5 domain 2-type fold; Ribosomal protein S5 domain 2-type fold, subgroup; Small GTP-binding protein; Translation elongation factor EFG/EF2; Translation elongation factor EFG/EF2, C-terminal; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation/initiation factor/Ribosomal, beta-barrel. Gene sequence location is 2L:7220272..7223079.","translational elongation ; GO:0006414 | inferred from sequence or structural similarity with UniProtKB:Q07803 <newline> translational elongation ; GO:0006414 | non-traceable author statement","mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:Q07803 <newline> mitochondrion ; GO:0005739 | non-traceable author statement","translation elongation factor activity ; GO:0003746 | inferred from sequence or structural similarity with UniProtKB:Q07803 <newline> translation elongation factor activity ; GO:0003746 | non-traceable author statement <newline> GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR000640, InterPro:IPR000795, InterPro:IPR004161, InterPro:IPR004540, InterPro:IPR005225, InterPro:IPR005517 <newline> GTPase activity ; GO:0003924 | inferred from electronic annotation with InterPro:IPR000795"]
["FBgn0051048","-","CG31048","This gene is referred to in FlyBase by the symbol Dmel\\CG31048 (FBgn0051048). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: GTP binding; GTPase binding; guanyl-nucleotide exchange factor activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Dedicator of cytokinesis; Src homology-3 domain. Gene sequence location is 3R:24671689..24695340.","-","-","GTP binding ; GO:0005525 | inferred from electronic annotation with InterPro:IPR010703 <newline> guanyl-nucleotide exchange factor activity ; GO:0005085 | inferred from electronic annotation with InterPro:IPR010703 <newline> GTPase binding ; GO:0051020 | inferred from electronic annotation with InterPro:IPR010703"]
["FBgn0031436","-","CG3214","This gene is referred to in FlyBase by the symbol Dmel\\CG3214 (FBgn0031436). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, NADH to ubiquinone. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: NADH:ubiquinone oxidoreductase, 17.2kDa subunit. Gene sequence location is 2L:2579217..2580056.","mitochondrial electron transport, NADH to ubiquinone ; GO:0006120 | inferred from sequence or structural similarity with UniProtKB:Q9UI09","mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with EMBL:AJ011400; protein_id:CAA09608 <newline> mitochondrial respiratory chain complex I ; GO:0005747 | inferred from sequence or structural similarity with UniProtKB:Q9UI09","NADH dehydrogenase (ubiquinone) activity ; GO:0008137 | inferred from sequence or structural similarity with EMBL:AJ011400; protein_id:CAA09608 <newline> NADH dehydrogenase activity ; GO:0003954 | inferred from sequence or structural similarity with UniProtKB:Q9UI09 <newline> electron carrier activity ; GO:0009055 | inferred from electronic annotation with InterPro:IPR007763"]
["FBgn0039125","-","CG5857","This gene is referred to in FlyBase by the symbol Dmel\\CG5857 (FBgn0039125). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Nucleoporin protein Ndc1-Nup. Gene sequence location is 3R:19750125..19752158.","-","-","-"]
["FBgn0051053","-","CG31053","This gene is referred to in FlyBase by the symbol Dmel\\CG31053 (FBgn0051053). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Gene sequence location is 3R:23753077..23753896.","-","-","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841"]
["FBgn0030191","-","CG15306","This gene is referred to in FlyBase by the symbol Dmel\\CG15306 (FBgn0030191). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Calponin homology domain. Gene sequence location is X:10224189..10225814.","-","-","-"]
["FBgn0027865","Tetraspanin 96F","Tsp96F","The gene Tetraspanin 96F is referred to in FlyBase by the symbol Dmel\\Tsp96F (CG6120, FBgn0027865). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Tetraspanin; Tetraspanin, EC2 domain; Tetraspanin, subgroup. Gene sequence location is 3R:21699256..21707162.","-","integral to membrane ; GO:0016021 | inferred from sequence or structural similarity <newline> integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR000301, InterPro:IPR008952, InterPro:IPR018499","-"]
["FBgn0034948","-","Gadd34","This gene is referred to in FlyBase by the symbol Dmel\\Gadd34 (CG3825, FBgn0034948). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Protein phosphatase 1, regulatory subunit 15A/B, C-terminal. Gene sequence location is 2R:19863124..19864801.","-","-","-"]
["FBgn0033454","-","CG1671","This gene is referred to in FlyBase by the symbol Dmel\\CG1671 (FBgn0033454). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: rRNA processing. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: G-protein beta WD-40 repeat; Small-subunit processome, Utp13; WD40 repeat; WD40 repeat 2; WD40 repeat, conserved site; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Gene sequence location is 2R:5735568..5738323.","rRNA processing ; GO:0006364 | inferred from electronic annotation with InterPro:IPR013934","small-subunit processome ; GO:0032040 | inferred from electronic annotation with InterPro:IPR013934","-"]
["FBgn0035842","-","CG7504","This gene is referred to in FlyBase by the symbol Dmel\\CG7504 (FBgn0035842). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent RNA helicase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Forkhead-associated (FHA) domain; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMAD/FHA domain. Gene sequence location is 3L:8124542..8130313.","-","microtubule associated complex ; GO:0005875 | inferred from direct assay","ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with SGD_LOCUS:SEN1; SGD:S0004422 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR006935 <newline> DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR006935"]
["FBgn0030717","-","CG8931","This gene is referred to in FlyBase by the symbol Dmel\\CG8931 (FBgn0030717). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Mitochondrial substrate carrier; Mitochondrial substrate/solute carrier. Gene sequence location is X:15877807..15879438.","transmembrane transport ; GO:0055085 | inferred from electronic annotation with InterPro:IPR001993","membrane ; GO:0016020 | inferred from electronic annotation with InterPro:IPR001993","binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR001993"]
["FBgn0037856","-","CG4674","This gene is referred to in FlyBase by the symbol Dmel\\CG4674 (FBgn0037856). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 17 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Arrestin-like, C-terminal; Arrestin-like, N-terminal; Immunoglobulin E-set. Gene sequence location is 3R:6711269..6722140.","-","-","-"]
["FBgn0085377","-","CG34348","This gene is referred to in FlyBase by the symbol Dmel\\CG34348 (FBgn0085377). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: acyltransferase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Phospholipid/glycerol acyltransferase. Gene sequence location is X:11234485..11238769.","metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR002123","-","acyltransferase activity ; GO:0008415 | inferred from electronic annotation with InterPro:IPR002123"]
["FBgn0085212","-","CG34183","This gene is referred to in FlyBase by the symbol Dmel\\CG34183 (FBgn0085212). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 2L:9890061..9890787.","-","-","-"]
["FBgn0029003","mab-21","mab-21","The gene mab-21 is referred to in FlyBase by the symbol Dmel\\mab-21 (CG4746, FBgn0029003). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Mab-21 protein; Mab-21 protein-related. Gene sequence location is X:5902216..5907211.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0030189","-","CG2909","This gene is referred to in FlyBase by the symbol Dmel\\CG2909 (FBgn0030189). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is X:10220504..10222979.","-","-","-"]
["FBgn0052533","-","CG32533","This gene is referred to in FlyBase by the symbol Dmel\\CG32533 (FBgn0052533). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: helicase activity; ATP-dependent RNA helicase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nuclear mRNA splicing, via spliceosome. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: DEAD-like helicase, N-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Domain of unknown function DUF1605; Helicase, C-terminal; Helicase, superfamily 1/2, ATP-binding domain; Helicase-associated domain. Gene sequence location is X:19368178..19373345.","nuclear mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with UniProtKB:P20095","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:P20095","helicase activity ; GO:0004386 | inferred from sequence or structural similarity with SGD_LOCUS:SGS1; SGD:S0004802 <newline> ATP-dependent RNA helicase activity ; GO:0004004 | inferred from sequence or structural similarity with UniProtKB:P20095 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001650, InterPro:IPR011545 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001650, InterPro:IPR011545"]
["FBgn0039804","-","CG15544","This gene is referred to in FlyBase by the symbol Dmel\\CG15544 (FBgn0039804). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 3R:26653572..26667756.","-","-","-"]
["FBgn0083949","-","CG34113","This gene is referred to in FlyBase by the symbol Dmel\\CG34113 (FBgn0083949). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: CD80-like, immunoglobulin C2-set; Immunoglobulin; Immunoglobulin subtype; Immunoglobulin-like. Gene sequence location is 3R:1688587..1765245.","-","-","-"]
["FBgn0036775","-","CG5147","This gene is referred to in FlyBase by the symbol Dmel\\CG5147 (FBgn0036775). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: DNA-directed RNA polymerase activity; DNA binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transcription from RNA polymerase III promoter. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: RNA polymerase III Rpc4. Gene sequence location is 3L:18100946..18102673.","transcription from RNA polymerase III promoter ; GO:0006383 | inferred from electronic annotation with InterPro:IPR007811","DNA-directed RNA polymerase III complex ; GO:0005666 | inferred from electronic annotation with InterPro:IPR007811","DNA binding ; GO:0003677 | inferred from electronic annotation with InterPro:IPR007811 <newline> DNA-directed RNA polymerase activity ; GO:0003899 | inferred from electronic annotation with InterPro:IPR007811"]
["FBgn0028343","lethal (1) G0222","l(1)G0222","The gene lethal (1) G0222 is referred to in FlyBase by the symbol Dmel\\l(1)G0222 (CG8465, FBgn0028343). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain. Gene sequence location is X:17465887..17473262.","-","-","-"]
["FBgn0034879","Rrp4","Rrp4","The gene Rrp4 is referred to in FlyBase by the symbol Dmel\\Rrp4 (CG3931, FBgn0034879). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: 3'-5'-exoribonuclease activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mRNA processing. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: RNA-binding domain, S1. Gene sequence location is 2R:19442541..19443724.","mRNA processing ; GO:0006397 | inferred from sequence or structural similarity with SGD_LOCUS:RRP4; SGD:S0001111","nuclear exosome (RNase complex) ; GO:0000176 | inferred from physical interaction with Spt6 AND inferred from sequence or structural similarity with SGD_LOCUS:RRP4; SGD:S0001111 <newline> cytoplasmic exosome (RNase complex) ; GO:0000177 | inferred from sequence or structural similarity with SGD_LOCUS:RRP4; SGD:S0001111 <newline> nuclear exosome (RNase complex) ; GO:0000176 | inferred from sequence or structural similarity with SGD_LOCUS:RRP4; SGD:S0001111 <newline> cytoplasm ; GO:0005737 | inferred from direct assay <newline> nuclear lamina ; GO:0005652 | inferred from direct assay","3'-5'-exoribonuclease activity ; GO:0000175 | inferred from sequence or structural similarity with SGD_LOCUS:RRP4; SGD:S0001111"]
["FBgn0052138","-","CG32138","This gene is referred to in FlyBase by the symbol Dmel\\CG32138 (FBgn0052138). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: actin cytoskeleton organization. 7 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Actin-binding FH2; Actin-binding FH2/DRF autoregulatory; Armadillo-type fold; Diaphanous FH3; Diaphanous GTPase-binding; Diaphanous autoregulatory; GTPase-binding/formin homology 3. Gene sequence location is 3L:14046869..14063469.","actin cytoskeleton organization ; GO:0030036 | inferred from electronic annotation with InterPro:IPR003104, InterPro:IPR010473","cellular_component ; GO:0005575 | no biological data available","actin binding ; GO:0003779 | inferred from sequence or structural similarity <newline> actin binding ; GO:0003779 | inferred from electronic annotation with InterPro:IPR003104, InterPro:IPR010472, InterPro:IPR010473 <newline> Rho GTPase binding ; GO:0017048 | inferred from electronic annotation with InterPro:IPR010473"]
["FBgn0016715","Rhythmically expressed gene 2","Reg-2","The gene Rhythmically expressed gene 2 is referred to in FlyBase by the symbol Dmel\\Reg-2 (CG3200, FBgn0016715). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: phosphoglycolate phosphatase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: HAD-like domain; HAD-superfamily hydrolase, subfamily IA, REG-2-like; HAD-superfamily hydrolase, subfamily IA, variant 1; Haloacid dehalogenase-like hydrolase. Gene sequence location is 3L:605165..606569.","metabolic process ; GO:0008152 | inferred from electronic annotation with InterPro:IPR005834, InterPro:IPR006439","-","phosphoglycolate phosphatase activity ; GO:0008967 | inferred from electronic annotation with InterPro:IPR006439"]
["FBgn0030617","-","CG9095","This gene is referred to in FlyBase by the symbol Dmel\\CG9095 (FBgn0030617). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: cell adhesion. 9 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: C-type lectin; C-type lectin fold; C-type lectin, conserved site; C-type lectin-like; Coagulation factor 5/8 type, C-terminal; Complement control module; Galactose-binding domain-like; Sushi/SCR/CCP. Gene sequence location is X:15033962..15057255.","cell adhesion ; GO:0007155 | inferred from electronic annotation with InterPro:IPR000421","-","binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR001304, InterPro:IPR016186, InterPro:IPR016187, InterPro:IPR018378"]
["FBgn0010482","lethal (2) 01289","l(2)01289","The gene lethal (2) 01289 is referred to in FlyBase by the symbol Dmel\\l(2)01289 (CG9432, FBgn0010482). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: protein disulfide isomerase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: cell redox homeostasis. 22 alleles are reported. No phenotypic data is available. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Thioredoxin domain; Thioredoxin fold; Thioredoxin-like; Thioredoxin-like fold. Gene sequence location is 2R:2608606..2628149.","cell redox homeostasis ; GO:0045454 | inferred from electronic annotation with InterPro:IPR013766, InterPro:IPR017936","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity","protein disulfide isomerase activity ; GO:0003756 | inferred from sequence or structural similarity with UniProtKB:Q14554"]
["FBgn0053260","-","CG33260","This gene is referred to in FlyBase by the symbol Dmel\\CG33260 (FBgn0053260). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 3L:14753679..14754944.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0035529","-","CG1319","This gene is referred to in FlyBase by the symbol Dmel\\CG1319 (FBgn0035529). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: electron carrier activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Adrenodoxin; Adrenodoxin, iron-sulphur binding site; Beta-grasp fold, ferredoxin-type; Ferredoxin. Gene sequence location is 3L:4292497..4293432.","-","mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P10109","electron carrier activity ; GO:0009055 | inferred from sequence or structural similarity with UniProtKB:P10109 <newline> 2 iron, 2 sulfur cluster binding ; GO:0051537 | inferred from electronic annotation with InterPro:IPR001055, InterPro:IPR018298"]
["FBgn0030048","-","CG12112","This gene is referred to in FlyBase by the symbol Dmel\\CG12112 (FBgn0030048). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is X:8452910..8454225.","-","-","-"]
["FBgn0039335","Vacuolar protein sorting 33B","Vps33B","The gene Vacuolar protein sorting 33B is referred to in FlyBase by the symbol Dmel\\Vps33B (CG5127, FBgn0039335). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. Based on sequence similarity, it is predicted to be involved in the biological process</span>: vesicle-mediated transport. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Sec1-like protein. Gene sequence location is 3R:21299238..21301478.","vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with EMBL:U35245 <newline> vesicle docking involved in exocytosis ; GO:0006904 | inferred from electronic annotation with InterPro:IPR001619","-","-"]
["FBgn0028746","-","CG18508","This gene is referred to in FlyBase by the symbol Dmel\\CG18508 (FBgn0028746). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is X:3066487..3067172.","-","-","-"]
["FBgn0031877","-","CG10399","This gene is referred to in FlyBase by the symbol Dmel\\CG10399 (FBgn0031877). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: hydroxymethylglutaryl-CoA lyase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: leucine metabolic process. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Aldolase-type TIM barrel; Pyruvate carboxyltransferase. Gene sequence location is 2L:6960426..6961552.","leucine metabolic process ; GO:0006551 | inferred from sequence or structural similarity with UniProtKB:P35914","mitochondrial matrix ; GO:0005759 | inferred from sequence or structural similarity with UniProtKB:P35914 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","hydroxymethylglutaryl-CoA lyase activity ; GO:0004419 | inferred from sequence or structural similarity with UniProtKB:P35914"]
["FBgn0032298","-","CG6724","This gene is referred to in FlyBase by the symbol Dmel\\CG6724 (FBgn0032298). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: G-protein beta WD-40 repeat; NLE; WD40 repeat; WD40 repeat 2; WD40 repeat, conserved site; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Gene sequence location is 2L:10768234..10769964.","-","-","-"]
["FBgn0039593","-","CG9989","This gene is referred to in FlyBase by the symbol Dmel\\CG9989 (FBgn0039593). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: metal ion binding; hydrolase activity; nucleic acid binding. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: DNA/RNA non-specific endonuclease; Extracellular Endonuclease, subunit A. Gene sequence location is 3R:24496458..24497743.","-","-","hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821 <newline> metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR001604, InterPro:IPR020821"]
["FBgn0036643","Syntaxin 8","Syx8","The gene Syntaxin 8 is referred to in FlyBase by the symbol Dmel\\Syx8 (CG4109, FBgn0036643). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: SNAP receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: synaptic vesicle docking involved in exocytosis; neurotransmitter secretion; vesicle-mediated transport. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Syntaxin 8; Target SNARE coiled-coil domain. Gene sequence location is 3L:16579208..16580199.","neurotransmitter secretion ; GO:0007269 | inferred from sequence or structural similarity with EMBL:AF115323; protein_id:AAD20831 <newline> vesicle-mediated transport ; GO:0016192 | inferred from sequence or structural similarity with EMBL:AF115323; protein_id:AAD20831 <newline> synaptic vesicle docking involved in exocytosis ; GO:0016081 | inferred from sequence or structural similarity","plasma membrane ; GO:0005886 | inferred from sequence or structural similarity with EMBL:AF115323; protein_id:AAD20831 <newline> plasma membrane ; GO:0005886 | inferred from sequence or structural similarity","SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity with EMBL:AF115323; protein_id:AAD20831 <newline> SNAP receptor activity ; GO:0005484 | inferred from sequence or structural similarity"]
["FBgn0037035","-","CG10589","This gene is referred to in FlyBase by the symbol Dmel\\CG10589 (FBgn0037035). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 3L:20920926..20922444.","-","-","-"]
["FBgn0034197","Chitin deacetylase-like 9","Cda9","The gene Chitin deacetylase-like 9 is referred to in FlyBase by the symbol Dmel\\Cda9 (CG15918, FBgn0034197). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: carbohydrate metabolic process. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Glycoside hydrolase/deacetylase, beta/alpha-barrel; Polysaccharide deacetylase. Gene sequence location is 2R:13016338..13017839.","carbohydrate metabolic process ; GO:0005975 | inferred from electronic annotation with InterPro:IPR002509, InterPro:IPR011330","-","hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ; GO:0016810 | inferred from electronic annotation with InterPro:IPR002509"]
["FBgn0037521","-","CG2993","This gene is referred to in FlyBase by the symbol Dmel\\CG2993 (FBgn0037521). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Arrestin-like, C-terminal; Arrestin-like, N-terminal; Immunoglobulin E-set. Gene sequence location is 3R:3631717..3635710.","phagocytosis, engulfment ; GO:0006911 | inferred from mutant phenotype","-","-"]
["FBgn0035338","-","CG13800","This gene is referred to in FlyBase by the symbol Dmel\\CG13800 (FBgn0035338). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Gene sequence location is 3L:2379062..2408752.","-","-","-"]
["FBgn0034565","-","CG15650","This gene is referred to in FlyBase by the symbol Dmel\\CG15650 (FBgn0034565). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 2R:16865233..16865742.","-","-","-"]
["FBgn0035982","-","CG4461","This gene is referred to in FlyBase by the symbol Dmel\\CG4461 (FBgn0035982). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. Based on sequence similarity, it is predicted to be involved in the biological process</span>: response to heat. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: HSP20-like chaperone; Heat shock protein Hsp20. Gene sequence location is 3L:9368530..9369393.","response to heat ; GO:0009408 | inferred from sequence or structural similarity with EMBL:U96099","-","-"]
["FBgn0083919","Z band alternatively spliced PDZ-motif protein 52","Zasp52","The gene Z band alternatively spliced PDZ-motif protein 52 is referred to in FlyBase by the symbol Dmel\\Zasp52 (CG30084, FBgn0083919). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: protein binding. The biological processes in which it is involved are not known. 19 alleles are reported. The phenotypes of these alleles are annotated with: Z disc; myofibril; embryonic somatic muscle; embryonic/larval somatic muscle. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: PDZ/DHR/GLGF; ZASP; Zinc finger, LIM-type. Gene sequence location is 2R:11650070..11704314.","-","muscle tendon junction ; GO:0005927 | inferred from direct assay <newline> Z disc ; GO:0030018 | inferred from direct assay","protein binding ; GO:0005515 | inferred from physical interaction with egg <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001781"]
["FBgn0034422","-","CG7137","This gene is referred to in FlyBase by the symbol Dmel\\CG7137 (FBgn0034422). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: methyltransferase activity. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Methyltransferase-related. Gene sequence location is 2R:15114835..15116118.","-","-","methyltransferase activity ; GO:0008168 | inferred from electronic annotation with InterPro:IPR007823"]
["FBgn0031022","-","CG12204","This gene is referred to in FlyBase by the symbol Dmel\\CG12204 (FBgn0031022). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is X:19387323..19388434.","-","-","-"]
["FBgn0031878","septin interacting protein 2","sip2","The gene septin interacting protein 2 is referred to in FlyBase by the symbol Dmel\\sip2 (CG9188, FBgn0031878). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function</span>: protein binding. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Gene sequence location is 2L:6961516..6964073.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","protein binding ; GO:0005515 | inferred from physical interaction with Sep1 AND inferred from physical interaction with Sep2"]
["FBgn0050055","-","CR30055","This gene is referred to in FlyBase by the symbol Dmel\\CR30055 (FBgn0050055). It is a non_protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts. Gene sequence location is 2R:8476808..8478387.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0036665","-","CG13024","This gene is referred to in FlyBase by the symbol Dmel\\CG13024 (FBgn0036665). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Gene sequence location is 3L:16802758..16822174.","-","-","-"]
["FBgn0034563","-","CG15649","This gene is referred to in FlyBase by the symbol Dmel\\CG15649 (FBgn0034563). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Gene sequence location is 2R:16860421..16861502.","-","-","-"]
["FBgn0052803","-","CG32803","This gene is referred to in FlyBase by the symbol Dmel\\CG32803 (FBgn0052803). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Gene sequence location is X:1794726..1795971.","-","-","-"]
["FBgn0259699","-","CG42353","This gene is referred to in FlyBase by the symbol Dmel\\CG42353 (FBgn0259699). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Gene sequence location is X:15987103..15998945.","-","-","-"]
["FBgn0250867","-","CG42238","This gene is referred to in FlyBase by the symbol Dmel\\CG42238 (FBgn0250867). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 11 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Gene sequence location is 2L:20965520..21051954.","-","-","-"]
["FBgn0050279","-","CG30279","This gene is referred to in FlyBase by the symbol Dmel\\CG30279 (FBgn0050279). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 2R:18066686..18067033.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0259244","-","CG42342","This gene is referred to in FlyBase by the symbol Dmel\\CG42342 (FBgn0259244). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 21 alleles are reported. No phenotypic data is available. It has 10 annotated transcripts and 10 annotated polypeptides. Protein features are: Collagen triple helix repeat. Gene sequence location is 3R:12328523..12397082.","-","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0037855","-","CG6621","This gene is referred to in FlyBase by the symbol Dmel\\CG6621 (FBgn0037855). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Tetratricopeptide repeat; Tetratricopeptide repeat-containing; Tetratricopeptide-like helical. Gene sequence location is 3R:6715490..6719252.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","binding ; GO:0005488 | inferred from electronic annotation with InterPro:IPR011990"]
["FBgn0038830","-","CG17272","This gene is referred to in FlyBase by the symbol Dmel\\CG17272 (FBgn0038830). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: calcium ion binding. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: EF-HAND 2; EF-hand-like domain. Gene sequence location is 3R:16649028..16649951.","-","-","calcium ion binding ; GO:0005509 | inferred from sequence or structural similarity with UniProtKB:Q40302"]
["FBgn0037548","-","CG7900","This gene is referred to in FlyBase by the symbol Dmel\\CG7900 (FBgn0037548). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: fatty acid amide hydrolase activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Amidase. Gene sequence location is 3R:3919846..3930805.","-","-","fatty acid amide hydrolase activity ; GO:0017064 | inferred from sequence or structural similarity with EMBL:U82536 <newline> carbon-nitrogen ligase activity, with glutamine as amido-N-donor ; GO:0016884 | inferred from electronic annotation with InterPro:IPR000120"]
["FBgn0052163","-","CG32163","This gene is referred to in FlyBase by the symbol Dmel\\CG32163 (FBgn0052163). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Acyl-CoA N-acyltransferase. Gene sequence location is 3L:16580433..16581243.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0027106","innexin 7","inx7","The gene innexin 7 is referred to in FlyBase by the symbol Dmel\\inx7 (CG2977, FBgn0027106). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: gap junction channel activity. The biological processes in which it is involved are not known. 32 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Innexin. Gene sequence location is X:6885645..6903902.","-","gap junction ; GO:0005921 | non-traceable author statement <newline> gap junction ; GO:0005921 | inferred from sequence or structural similarity with EMBL:AF115854 <newline> integral to membrane ; GO:0016021 | non-traceable author statement <newline> gap junction ; GO:0005921 | inferred from direct assay","gap junction channel activity ; GO:0005243 | inferred from sequence or structural similarity with EMBL:AF115854 <newline> gap junction channel activity ; GO:0005243 | non-traceable author statement"]
["FBgn0034705","-","CG11170","This gene is referred to in FlyBase by the symbol Dmel\\CG11170 (FBgn0034705). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: ATPase activity; ATP binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: ABC transporter, conserved site. Gene sequence location is 2R:18064924..18070337.","-","-","ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR017871 <newline> ATPase activity ; GO:0016887 | inferred from electronic annotation with InterPro:IPR017871"]
["FBgn0039944","-","CG17162","This gene is referred to in FlyBase by the symbol Dmel\\CG17162 (FBgn0039944). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Gene sequence location is XHet:64549..75553.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0040522","-","CG10928","This gene is referred to in FlyBase by the symbol Dmel\\CG10928 (FBgn0040522).The gene previously had a gene model which is not supported by current evidence. It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available.. Gene has not been localized to the genome sequence.","-","-","-"]
["FBgn0043455","-","CG5986","This gene is referred to in FlyBase by the symbol Dmel\\CG5986 (FBgn0043455). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotypes of these alleles are annotated with: eye; dorsocentral bristle; scutellar bristle. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 3R:19873512..19874891.","-","-","-"]
["FBgn0031875","-","CG3430","This gene is referred to in FlyBase by the symbol Dmel\\CG3430 (FBgn0031875). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Protein of unknown function DUF2044, membrane. Gene sequence location is 2L:6957010..6959104.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0002773","Myosin light chain 2","Mlc2","The gene Myosin light chain 2 is referred to in FlyBase by the symbol Dmel\\Mlc2 (CG2184, FBgn0002773). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled. The biological processes in which it is involved are not known. 14 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Calcium-binding EF-hand; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand-like domain. Gene sequence location is 3R:25997160..26000273.","-","myosin complex ; GO:0016459 | inferred from sequence or structural similarity <newline> muscle myosin complex ; GO:0005859 | non-traceable author statement","ATPase activity, coupled ; GO:0042623 | inferred from sequence or structural similarity <newline> microfilament motor activity ; GO:0000146 | non-traceable author statement <newline> calcium ion binding ; GO:0005509 | non-traceable author statement <newline> calcium ion binding ; GO:0005509 | inferred from electronic annotation with InterPro:IPR002048, InterPro:IPR011992"]
["FBgn0051869","-","CG31869","This gene is referred to in FlyBase by the symbol Dmel\\CG31869 (FBgn0051869). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: von Willebrand factor, type C. Gene sequence location is 2L:10772038..10801107.","-","-","-"]
["FBgn0053082","-","CG33082","This gene is referred to in FlyBase by the symbol Dmel\\CG33082 (FBgn0053082). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: RNAse P, Rpr2/Rpp21 subunit. Gene sequence location is X:924791..925645.","-","-","-"]
["FBgn0030645","-","CG6308","This gene is referred to in FlyBase by the symbol Dmel\\CG6308 (FBgn0030645). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Oligosaccharide biosynthesis protein Alg14-like. Gene sequence location is X:15366197..15366892.","-","-","-"]
["FBgn0037718","P58IPK","P58IPK","The gene P58IPK is referred to in FlyBase by the symbol Dmel\\P58IPK (CG8286, FBgn0037718). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: protein kinase inhibitor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: protein folding. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Heat shock protein DnaJ; Heat shock protein DnaJ, N-terminal; Molecular chaperone, heat shock protein, Hsp40, DnaJ; Tetratricopeptide TPR-1; Tetratricopeptide repeat; Tetratricopeptide repeat-containing; Tetratricopeptide-like helical. Gene sequence location is 3R:5412661..5415303.","protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR003095","-","protein kinase inhibitor activity ; GO:0004860 | inferred from sequence or structural similarity with EMBL:U28423 <newline> unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR003095 <newline> heat shock protein binding ; GO:0031072 | inferred from electronic annotation with InterPro:IPR001623, InterPro:IPR003095"]
["FBgn0035410","-","CG14964","This gene is referred to in FlyBase by the symbol Dmel\\CG14964 (FBgn0035410). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: myosin binding. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin-like; Immunoglobulin-like fold. Gene sequence location is 3L:3173263..3177906.","-","-","myosin binding ; GO:0017022 | inferred from sequence or structural similarity with EMBL:AF059576"]
["FBgn0037796","-","CG12814","This gene is referred to in FlyBase by the symbol Dmel\\CG12814 (FBgn0037796). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Endoglin/CD105 antigen. Gene sequence location is 3R:5996878..6015315.","-","-","-"]
["FBgn0038256","-","CG7530","This gene is referred to in FlyBase by the symbol Dmel\\CG7530 (FBgn0038256). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Hly-III-related. Gene sequence location is 3R:10550472..10557231.","-","integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR004254","-"]
["FBgn0260763","-","CG42561","This gene is referred to in FlyBase by the symbol Dmel\\CG42561 (FBgn0260763). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 2R:13572223..13573053.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0038168","oocyte maintenance defects","omd","The gene oocyte maintenance defects is referred to in FlyBase by the symbol Dmel\\omd (CG9591, FBgn0038168). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 15 alleles are reported. The phenotypes of these alleles are annotated with: wing; wing vein. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 3R:9505151..9512932.","-","-","-"]
["FBgn0034742","-","CG4294","This gene is referred to in FlyBase by the symbol Dmel\\CG4294 (FBgn0034742). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: magnesium ion binding; inorganic diphosphatase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: phosphate metabolic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Inorganic pyrophosphatase. Gene sequence location is 2R:18487910..18493140.","phosphate metabolic process ; GO:0006796 | inferred from electronic annotation with InterPro:IPR008162","cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR008162","inorganic diphosphatase activity ; GO:0004427 | inferred from electronic annotation with InterPro:IPR008162 <newline> magnesium ion binding ; GO:0000287 | inferred from electronic annotation with InterPro:IPR008162"]
["FBgn0052446","-","Atox1","This gene is referred to in FlyBase by the symbol Dmel\\Atox1 (CG32446, FBgn0052446). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: metal ion binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metal ion transport. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Heavy metal transport/detoxification protein. Gene sequence location is 3L:21634142..21635699.","metal ion transport ; GO:0030001 | inferred from electronic annotation with InterPro:IPR006121","-","metal ion binding ; GO:0046872 | inferred from electronic annotation with InterPro:IPR006121"]
["FBgn0021768","nudC","nudC","The gene nudC is referred to in FlyBase by the symbol Dmel\\nudC (CG9710, FBgn0021768). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nuclear migration. 10 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: CS domain; CS-like domain; HSP20-like chaperone. Gene sequence location is 3L:16798094..16812632.","nuclear migration ; GO:0007097 | non-traceable author statement <newline> nuclear migration ; GO:0007097 | inferred from sequence or structural similarity with UniProtKB:P17624 <newline> oogenesis ; GO:0048477 | non-traceable author statement","cytoplasm ; GO:0005737 | inferred from direct assay <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","-"]
["FBgn0051141","-","CG31141","This gene is referred to in FlyBase by the symbol Dmel\\CG31141 (FBgn0051141). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. Based on sequence similarity, it is predicted to be involved in the biological process</span>: fatty acid elongation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: GNS1/SUR4 membrane protein. Gene sequence location is 3R:19749022..19750041.","fatty acid elongation ; GO:0030497 | inferred from sequence or structural similarity with HGNC_gene:ELOVL4; HGNC:14415; OMIM:605512 AND inferred from sequence or structural similarity with UniProtKB:Q95K73","integral to membrane ; GO:0016021 | inferred from electronic annotation with InterPro:IPR002076","-"]
["FBgn0001230","Heat shock protein 68","Hsp68","The gene Heat shock protein 68 is referred to in FlyBase by the symbol Dmel\\Hsp68 (CG5436, FBgn0001230). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: unfolded protein binding. There is experimental evidence that it is involved in the biological process</span>: determination of adult lifespan. 10 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Heat shock protein 70; Heat shock protein 70, conserved site; Heat shock protein Hsp70. Gene sequence location is 3R:19880802..19883029.","determination of adult lifespan ; GO:0008340 | inferred from mutant phenotype <newline> response to heat ; GO:0009408 | inferred from sequence or structural similarity with MGD:Hspa1b; MGI:MGI:99517 <newline> response to heat ; GO:0009408 | non-traceable author statement <newline> protein folding ; GO:0006457 | inferred from sequence or structural similarity with UniProtKB:P38646","lipid particle ; GO:0005811 | inferred from direct assay <newline> mitochondrion ; GO:0005739 | inferred from sequence or structural similarity with UniProtKB:P38646 <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay","unfolded protein binding ; GO:0051082 | inferred from sequence or structural similarity with UniProtKB:P38646 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001023"]
["FBgn0035121","Tudor-SN","Tudor-SN","The gene Tudor-SN is referred to in FlyBase by the symbol Dmel\\Tudor-SN (CG7008, FBgn0035121). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: transcription coactivator activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: gene silencing by RNA. 14 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Maternal tudor protein; RNA-induced silencing complex, nuclease component Tudor-SN; Staphylococcal nuclease (SNase-like); Staphylococcal nuclease (SNase-like), OB-fold; Tudor domain; Tudor subgroup. Gene sequence location is 3L:259286..264378.","gene silencing by RNA ; GO:0031047 | inferred from electronic annotation with InterPro:IPR016685","lipid particle ; GO:0005811 | inferred from direct assay <newline> RNA-induced silencing complex ; GO:0016442 | traceable author statement <newline> microtubule associated complex ; GO:0005875 | inferred from direct assay <newline> RNA-induced silencing complex ; GO:0016442 | inferred from electronic annotation with InterPro:IPR016685","transcription coactivator activity ; GO:0003713 | inferred from sequence or structural similarity with EMBL:U22055 <newline> hydrolase activity, acting on ester bonds ; GO:0016788 | inferred from electronic annotation with InterPro:IPR006021, InterPro:IPR016071 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR002999, InterPro:IPR006021, InterPro:IPR016071"]
["FBgn0035950","-","CG5288","This gene is referred to in FlyBase by the symbol Dmel\\CG5288 (FBgn0035950). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: galactokinase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: galactose metabolic process; carbohydrate phosphorylation. 5 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: GHMP kinase; GHMP kinase, ATP-binding, conserved site; GHMP kinase, C-terminal; Galactokinase; Galactokinase galactose-binding domain; Galactokinase, conserved site; Mevalonate/galactokinase; Ribosomal protein S5 domain 2-type fold; Ribosomal protein S5 domain 2-type fold, subgroup. Gene sequence location is 3L:8976254..8979189.","galactose metabolic process ; GO:0006012 | inferred from electronic annotation with InterPro:IPR000705 <newline> carbohydrate phosphorylation ; GO:0046835 | inferred from electronic annotation with InterPro:IPR000705","cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR006206","galactokinase activity ; GO:0004335 | inferred from sequence or structural similarity with NCBI_gi:4503897 <newline> ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR000705, InterPro:IPR006203, InterPro:IPR006204, InterPro:IPR006206"]
["FBgn0037350","-","CG2911","This gene is referred to in FlyBase by the symbol Dmel\\CG2911 (FBgn0037350). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: heat shock protein binding; unfolded protein binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: protein folding. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Heat shock protein DnaJ; Heat shock protein DnaJ, N-terminal; Heat shock protein DnaJ, conserved site; Molecular chaperone, heat shock protein, Hsp40, DnaJ; Zinc finger, DPH-type. Gene sequence location is 3R:1447834..1449810.","protein folding ; GO:0006457 | inferred from electronic annotation with InterPro:IPR003095","-","heat shock protein binding ; GO:0031072 | inferred from electronic annotation with InterPro:IPR001623, InterPro:IPR003095, InterPro:IPR018253 <newline> unfolded protein binding ; GO:0051082 | inferred from electronic annotation with InterPro:IPR003095"]
["FBgn0026878","-","CG4325","This gene is referred to in FlyBase by the symbol Dmel\\CG4325 (FBgn0026878). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding. There is experimental evidence that it is involved in the biological process</span>: regulation of antimicrobial peptide biosynthetic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Zinc finger, C3HC4 RING-type; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type. Gene sequence location is X:1937077..1937851.","regulation of antimicrobial peptide biosynthetic process ; GO:0002805 | inferred from mutant phenotype","-","zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR001841"]
["FBgn0011742","Actin-related protein 14D","Arp14D","The gene Actin-related protein 14D is referred to in FlyBase by the symbol Dmel\\Arp14D (CG9901, FBgn0011742). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of cytoskeleton; actin binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: cytoskeleton organization. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Actin-like; Actin/actin-like conserved site. Gene sequence location is X:16442247..16448001.","cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity <newline> cytoskeleton organization ; GO:0007010 | inferred from sequence or structural similarity with SGD_LOCUS:ARP2; SGD:S0002187 <newline> regulation of actin polymerization or depolymerization ; GO:0008064 | non-traceable author statement","actin filament ; GO:0005884 | inferred from sequence or structural similarity with SGD_LOCUS:ARP2; SGD:S0002187 <newline> Arp2/3 protein complex ; GO:0005885 | non-traceable author statement <newline> Arp2/3 protein complex ; GO:0005885 | inferred from sequence or structural similarity <newline> Arp2/3 protein complex ; GO:0005885 | inferred from sequence or structural similarity with SGD_LOCUS:ARP2; SGD:S0002187 <newline> actin cytoskeleton ; GO:0015629 | non-traceable author statement","structural constituent of cytoskeleton ; GO:0005200 | inferred from sequence or structural similarity <newline> actin binding ; GO:0003779 | inferred from sequence or structural similarity with SGD_LOCUS:ARP2; SGD:S0002187"]
["FBgn0044030","mitochondrial ribosomal protein S14","mRpS14","The gene mitochondrial ribosomal protein S14 is referred to in FlyBase by the symbol Dmel\\mRpS14 (CG32531, FBgn0044030). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of ribosome. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translation. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Ribosomal protein S14. Gene sequence location is X:19373415..19373950.","translation ; GO:0006412 | inferred from sequence or structural similarity with protein_id:CAB16601","mitochondrial small ribosomal subunit ; GO:0005763 | inferred from sequence or structural similarity with protein_id:CAB16601 <newline> mitochondrial ribosome ; GO:0005761 | inferred from sequence or structural similarity with UniProtKB:O60783","structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with protein_id:CAB16601 <newline> structural constituent of ribosome ; GO:0003735 | inferred from sequence or structural similarity with UniProtKB:O60783"]
["FBgn0037469","Dephospho-CoA kinase","Dpck","The gene Dephospho-CoA kinase is referred to in FlyBase by the symbol Dmel\\Dpck (CG1939, FBgn0037469). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: ATP binding; dephospho-CoA kinase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: coenzyme A biosynthetic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Dephospho-CoA kinase. Gene sequence location is 3R:2907911..2908973.","coenzyme A biosynthetic process ; GO:0015937 | inferred from electronic annotation with InterPro:IPR001977","-","ATP binding ; GO:0005524 | inferred from electronic annotation with InterPro:IPR001977 <newline> dephospho-CoA kinase activity ; GO:0004140 | inferred from electronic annotation with InterPro:IPR001977"]
["FBgn0034564","-","CG9344","This gene is referred to in FlyBase by the symbol Dmel\\CG9344 (FBgn0034564). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nuclear mRNA splicing, via spliceosome. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Like-Sm ribonucleoprotein (LSM) domain; Like-Sm ribonucleoprotein (LSM) domain, eukaryotic/archaea-type; Like-Sm ribonucleoprotein (LSM)-related domain. Gene sequence location is 2R:16864561..16865105.","nuclear mRNA splicing, via spliceosome ; GO:0000398 | inferred from sequence or structural similarity with NCBI_NP:009011 AND inferred from sequence or structural similarity with SGD_LOCUS:LSM6; SGD:S0002786","small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with NCBI_gi:4507131 <newline> small nuclear ribonucleoprotein complex ; GO:0030532 | inferred from sequence or structural similarity with NCBI_NP:009011 AND inferred from sequence or structural similarity with SGD_LOCUS:LSM6; SGD:S0002786 <newline> U6 snRNP ; GO:0005688 | non-traceable author statement <newline> spliceosomal complex ; GO:0005681 | inferred from sequence or structural similarity with NCBI_NP:009011 AND inferred from sequence or structural similarity with SGD_LOCUS:LSM6; SGD:S0002786","-"]
["FBgn0037338","Snm1","Snm1","The gene Snm1 is referred to in FlyBase by the symbol Dmel\\Snm1 (CG10018, FBgn0037338). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: hydrolase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: DNA repair. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Beta-lactamase-like; DNA repair metallo-beta-lactamase. Gene sequence location is 3R:1380812..1383508.","DNA repair ; GO:0006281 | inferred from sequence or structural similarity with SGD_LOCUS:PSO2; SGD:S0004745","-","hydrolase activity ; GO:0016787 | inferred from electronic annotation with InterPro:IPR001279"]
["FBgn0030863","-","CG8188","This gene is referred to in FlyBase by the symbol Dmel\\CG8188 (FBgn0030863). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquitin-protein ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: post-translational protein modification. 11 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Ubiquitin-conjugating enzyme, E2; Ubiquitin-conjugating enzyme, active site; Ubiquitin-conjugating enzyme/RWD-like. Gene sequence location is X:17593805..17596994.","post-translational protein modification ; GO:0043687 | inferred from electronic annotation with InterPro:IPR000608","-","ubiquitin-protein ligase activity ; GO:0004842 | inferred from sequence or structural similarity with NCBI_gi:345829"]
["FBgn0051472","-","CG31472","This gene is referred to in FlyBase by the symbol Dmel\\CG31472 (FBgn0051472). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: pyridoxamine-phosphate oxidase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: pyridoxine biosynthetic process. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: FMN-binding split barrel; FMN-binding split barrel-related; Pyridoxamine 5'-phosphate oxidase; Pyridoxamine 5'-phosphate oxidase, conserved site; Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal. Gene sequence location is 3R:3636285..3637634.","pyridoxine biosynthetic process ; GO:0008615 | inferred from sequence or structural similarity with EMBL:U91561 <newline> oxidation-reduction process ; GO:0055114 | inferred from electronic annotation with InterPro:IPR000659, InterPro:IPR019576, InterPro:IPR019740","-","pyridoxamine-phosphate oxidase activity ; GO:0004733 | inferred from sequence or structural similarity with EMBL:U91561 <newline> FMN binding ; GO:0010181 | inferred from electronic annotation with InterPro:IPR011576, InterPro:IPR012349"]
["FBgn0031489","-","CG17224","This gene is referred to in FlyBase by the symbol Dmel\\CG17224 (FBgn0031489). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: uridine phosphorylase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: nucleotide catabolic process; nucleoside metabolic process. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Nucleoside phosphorylase; Nucleoside phosphorylase domain; Uridine phosphorylase, eukaryotic. Gene sequence location is 2L:3016591..3018304.","nucleoside metabolic process ; GO:0009116 | inferred from electronic annotation with InterPro:IPR000845 <newline> nucleotide catabolic process ; GO:0009166 | inferred from electronic annotation with InterPro:IPR010059","cytoplasm ; GO:0005737 | inferred from electronic annotation with InterPro:IPR010059","uridine phosphorylase activity ; GO:0004850 | inferred from sequence or structural similarity with NCBI_NP:853628"]
["FBgn0025390","Mucin related 2B","Mur2B","The gene Mucin related 2B is referred to in FlyBase by the symbol Dmel\\Mur2B (CG14796, FBgn0025390). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: chitin binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: chitin metabolic process. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Chitin binding domain. Gene sequence location is X:1417933..1512188.","chitin metabolic process ; GO:0006030 | inferred from electronic annotation with InterPro:IPR002557","chorion ; GO:0042600 | inferred from direct assay <newline> extracellular region ; GO:0005576 | inferred from electronic annotation with InterPro:IPR002557","chitin binding ; GO:0008061 | inferred from electronic annotation with InterPro:IPR002557"]
["FBgn0034082","-","CG10734","This gene is referred to in FlyBase by the symbol Dmel\\CG10734 (FBgn0034082). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Gene sequence location is 2R:12044772..12046299.","biological_process ; GO:0008150 | no biological data available","cellular_component ; GO:0005575 | no biological data available","molecular_function ; GO:0003674 | no biological data available"]
["FBgn0261705","-","CG42741","This gene is referred to in FlyBase by the symbol Dmel\\CG42741 (FBgn0261705). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: regulation of transcription. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Zinc finger, C2H2-like; Zinc finger, C2H2-type; Zinc finger, C2H2-type/integrase, DNA-binding. Gene sequence location is 2R:18899290..18929143.",null,"regulation of transcription ; GO:0045449 | inferred from sequence or structural similarity with UniProtKB:O35739","nucleus ; GO:0005634 | inferred from sequence or structural similarity with UniProtKB:O35739","sequence-specific DNA binding transcription factor activity ; GO:0003700 | inferred from sequence or structural similarity with UniProtKB:O35739 <newline> zinc ion binding ; GO:0008270 | inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 <newline> nucleic acid binding ; GO:0003676 | inferred from electronic annotation with InterPro:IPR013087"]