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{"sheet":"Supplementary Table S4","index":0,"n_rows":381,"n_cols":3,"rows_kept":381,"merged":[[0,0,0,2]],"flags":["formulas_cached_only"]}
["Table S4. Drug simialrity network (similarity ≥0.4)"]
["Drug name","Drug name","simialrity"]
["halcinonide","flumethasone",0.877561931]
["halcinonide","hydrocortisone 17-butyrate",1]
["halcinonide","amcinonide",0.675116518]
["halcinonide","prednicarbate",0.787635938]
["halcinonide","clocortolone",0.946320447]
["halcinonide","alclometasone",0.961963167]
["halcinonide","fluocinonide",0.622676121]
["halcinonide","desonide",0.820589321]
["halcinonide","desoximetasone",0.66174655]
["halcinonide","Halobetasol",0.912303752]
["halcinonide","mometasone",0.407741464]
["halcinonide","flurandrenolone",0.807024789]
["dicloxacillin","penicillin",0.446376287]
["dicloxacillin","oxacillin",0.868744486]
["dyphylline","choline theophyllinate",0.654830714]
["olmesartan medoxomil","chlorthalidone",0.648491057]
["olmesartan medoxomil","thiazide",0.779120349]
["olmesartan medoxomil","polythiazide",0.639298915]
["olmesartan medoxomil","hydroflumethiazide",0.639298915]
["1,25-dihydroxyvitamin D3","doxercalciferol",0.451496027]
["pizotifen","primaquine",0.426561704]
["pizotifen","griseofulvin",0.494913398]
["tetracycline","penicillin V",0.425072828]
["tetracycline","demeclocycline",0.415536935]
["tetracycline","minocycline",0.401912472]
["tetracycline","ampicillin",0.452634564]
["tetracycline","oxytetracycline",0.670033175]
["rimexolone","medrysone",0.40138298]
["rimexolone","epitopic",0.583457156]
["rimexolone","loteprednol",0.537020065]
["trifluoperazine","thioridazine",0.417264377]
["trifluoperazine","prochlorperazine",0.957396482]
["trifluoperazine","thiothixene",0.511559793]
["trifluoperazine","perphenazine",0.577405703]
["trifluoperazine","chlorpromazine",0.764049174]
["trifluoperazine","fluphenazine",0.437461782]
["atenolol","acebutolol",0.418258005]
["mepenzolate methylbromide","orphenadrine",0.428958479]
["mepenzolate methylbromide","methylscopolamine",0.991902701]
["mepenzolate methylbromide","dicyclomine",0.485699536]
["mepenzolate methylbromide","propantheline",0.921155442]
["mepenzolate methylbromide","glycopyrrolate",0.47482054]
["fluoxetine","duloxetine",0.490001866]
["fluoxetine","pregabalin",0.401575965]
["fluoxetine","paroxetine",0.408536679]
["fluoxetine","venlafaxine",0.402421322]
["vardenafil","sildenafil",0.41281516]
["vardenafil","tadalafil",0.526303467]
["fosamprenavir","amprenavir",0.587802429]
["ceftizoxime","cefprozil",0.479868691]
["ceftizoxime","cefotetan",0.535349279]
["ceftizoxime","cephalexin",0.461603007]
["ceftizoxime","ceftazidime",0.48856112]
["ceftizoxime","cefadroxil",0.454460534]
["ceftizoxime","cefixime",0.429197538]
["lidocaine","mepivacaine",0.487772386]
["lidocaine","bupivacaine",0.44965194]
["amitriptyline","desipramine",0.490617642]
["amitriptyline","amoxapine",0.618879174]
["amitriptyline","nortriptyline",0.627199642]
["amitriptyline","cyclobenzaprine",0.527515884]
["amitriptyline","protriptyline",0.691004191]
["amitriptyline","imipramine",0.640496596]
["sodium iothalamate","ioxaglate",0.869675248]
["mefenamic acid","oxaprozin",0.642179585]
["mefenamic acid","etodolac",0.598358834]
["mefenamic acid","ketorolac",0.42198869]
["mefenamic acid","piroxicam",0.74186108]
["moexipril","benazepril",0.481455554]
["cefditoren","cefotetan",0.414991909]
["cefditoren","cefaclor",0.476602538]
["cefditoren","cefadroxil",0.427893909]
["cefditoren","cefixime",0.408400073]
["methimazole","propylthiouracil",0.474075998]
["ursodeoxycholic acid","anagrelide",0.437705442]
["flurazepam","nitrazepam",0.469010163]
["acebutolol","nadolol",0.426074646]
["acebutolol","metoprolol",0.46497433]
["acebutolol","propranolol",0.477360121]
["vecuronium","pancuronium",0.5804918]
["thioridazine","prochlorperazine",0.468417672]
["thioridazine","thiothixene",0.433951922]
["thioridazine","perphenazine",0.498805262]
["thioridazine","chlorpromazine",0.407444884]
["acetazolamide","methazolamide",0.759312569]
["selenium","monobenzyl ether of hydroquinone",0.589661894]
["penciclovir","docosanol",0.429376931]
["flumethasone","hydrocortisone 17-butyrate",0.877561931]
["flumethasone","amcinonide",0.769309258]
["flumethasone","prednicarbate",0.75309776]
["flumethasone","clocortolone",0.830454799]
["flumethasone","alclometasone",0.844182254]
["flumethasone","fluocinonide",0.731669692]
["flumethasone","desonide",0.720117949]
["flumethasone","desoximetasone",0.58072358]
["flumethasone","Halobetasol",0.800603043]
["flumethasone","flurandrenolone",0.944285642]
["orphenadrine","methylscopolamine",0.432460239]
["cefprozil","cefotetan",0.500549056]
["cefprozil","cefoxitin",0.408361347]
["cefprozil","cephalexin",0.473757124]
["cefprozil","cefadroxil",0.593268116]
["cefprozil","cephem",0.467253534]
["cefprozil","cefixime",0.55392481]
["prednisone","fludrocortisone",0.611584763]
["prednisone","adrenocorticotrophin",0.400280543]
["prednisone","methylprednisolone",0.588036575]
["prednisone","prednisolone",0.554720543]
["prednisone","cortisol",0.564726565]
["prednisone","triamcinolone",0.42311985]
["prednisone","cortisone",0.585636851]
["prednisone","dexamethasone",0.532677627]
["chlorpropamide","glibenclamide",0.403543793]
["chlorpropamide","tolazamide",0.610499035]
["chlorpropamide","glipizide",0.478618565]
["cefotetan","cefoxitin",0.673833436]
["cefotetan","cefotaxime",0.482126692]
["cefotetan","cephalexin",0.463099109]
["cefotetan","ceftazidime",0.425165426]
["cefotetan","cefadroxil",0.714147089]
["cefotetan","cefixime",0.67371007]
["cefotetan","cefazolin",0.429561401]
["phenoxybenzamine","chloride",0.413793103]
["rabeprazole","pregabalin",0.4053979]
["cefaclor","cefadroxil",0.433653614]
["cefaclor","cefixime",0.402339899]
["theophylline","aminophylline",0.883951496]
["methyltestosterone","fluoxymesterone",0.882759432]
["glibenclamide","tolazamide",0.666038548]
["glibenclamide","glimepiride",0.543543794]
["timolol","dorzolamide",0.495277842]
["loxapine","thiothixene",0.407535858]
["loxapine","molindone",0.426811868]
["chlorthalidone","thiazide",0.827069508]
["chlorthalidone","polythiazide",0.977824294]
["chlorthalidone","hydroflumethiazide",0.977824294]
["chlorthalidone","metolazone",0.427316922]
["medrysone","prednisolone",0.464415752]
["medrysone","fluorometholone",0.974888075]
["insulin lispro","insulin aspart",0.552968892]
["insulin lispro","insulin glargine",0.555903984]
["estradiol","conjugated estrogens",0.425177727]
["phentermine","diethylpropion",0.654459232]
["methylscopolamine","dicyclomine",0.481365097]
["methylscopolamine","propantheline",0.928675204]
["methylscopolamine","glycopyrrolate",0.470975776]
["desipramine","amoxapine",0.478482812]
["desipramine","nortriptyline",0.625302264]
["desipramine","protriptyline",0.64054957]
["desipramine","imipramine",0.639369718]
["primaquine","trimethoprim",0.438192068]
["primaquine","paromomycin",0.447213595]
["primaquine","carbenicillin indanyl sodium",0.406578556]
["primaquine","carbenicillin",0.406578556]
["hydrocortisone 17-butyrate","amcinonide",0.675116518]
["hydrocortisone 17-butyrate","prednicarbate",0.787635938]
["hydrocortisone 17-butyrate","clocortolone",0.946320447]
["hydrocortisone 17-butyrate","alclometasone",0.961963167]
["hydrocortisone 17-butyrate","fluocinonide",0.622676121]
["hydrocortisone 17-butyrate","desonide",0.820589321]
["hydrocortisone 17-butyrate","desoximetasone",0.66174655]
["hydrocortisone 17-butyrate","Halobetasol",0.912303752]
["hydrocortisone 17-butyrate","mometasone",0.407741464]
["hydrocortisone 17-butyrate","flurandrenolone",0.807024789]
["fludrocortisone","adrenocorticotrophin",0.521447885]
["fludrocortisone","methylprednisolone",0.637225619]
["fludrocortisone","prednisolone",0.612609233]
["fludrocortisone","cortisol",0.592995575]
["fludrocortisone","triamcinolone",0.450053103]
["fludrocortisone","cortisone",0.783096055]
["fludrocortisone","dexamethasone",0.564702507]
["cefoxitin","cefotaxime",0.47862862]
["cefoxitin","cephalexin",0.415589543]
["cefoxitin","cefadroxil",0.59603362]
["cefoxitin","cefixime",0.597480953]
["zopiclone","tiagabine",0.417289417]
["cefotaxime","cefadroxil",0.421747972]
["cefotaxime","cefixime",0.481305895]
["fluvoxamine","nefazodone",0.420235408]
["fluvoxamine","tiagabine",0.444370657]
["fosphenytoin","phenytoin",0.818694932]
["rapamycin","mycophenolic acid",0.436525553]
["sertaconazole","naftifine",0.57989137]
["sertaconazole","docosanol",0.465240202]
["pregabalin","paroxetine",0.400891669]
["irbesartan","hydrochlorothiazide",0.603324208]
["enflurane","isoflurane",0.504918576]
["enflurane","succinylcholine",0.406139414]
["adrenocorticotrophin","cortisone",0.511117832]
["insulin aspart","insulin glargine",0.569686701]
["amcinonide","prednicarbate",0.646825397]
["amcinonide","clocortolone",0.638876565]
["amcinonide","alclometasone",0.649437224]
["amcinonide","fluocinonide",0.562880268]
["amcinonide","desonide",0.644947546]
["amcinonide","desoximetasone",0.766820046]
["amcinonide","Halobetasol",0.717031104]
["amcinonide","mometasone",0.402638116]
["amcinonide","flurandrenolone",0.726447687]
["amcinonide","clobetasol",0.475304148]
["losartan","thiazide",0.414503483]
["clemastine","chlorpheniramine",0.982141421]
["clemastine","cyproheptadine",0.846568988]
["clemastine","carbinoxamine maleate",1]
["clemastine","diphenhydramine",0.931266147]
["cytokinin","pramlintide",0.632455532]
["fluvastatin","lovastatin",0.788782404]
["fluvastatin","pravastatin",0.616399653]
["fluvastatin","simvastatin",0.71117]
["fluvastatin","cerivastatin",0.764907847]
["sildenafil","tadalafil",0.401278398]
["oxymetholone","fluoxymesterone",0.454090783]
["oxymetholone","19-nortestosterone",0.775494734]
["quetiapine","olanzapine",0.421522974]
["prednicarbate","clocortolone",0.745355992]
["prednicarbate","alclometasone",0.757676761]
["prednicarbate","fluocinonide",0.660849935]
["prednicarbate","desonide",0.75726213]
["prednicarbate","desoximetasone",0.587339702]
["prednicarbate","Halobetasol",0.809724227]
["prednicarbate","flurandrenolone",0.699205899]
["prednicarbate","clobetasol",0.461283376]
["neostigmine","lactulose",0.413184338]
["exemestane","anastrozole",0.402566347]
["clocortolone","alclometasone",0.901760524]
["clocortolone","fluocinonide",0.579929658]
["clocortolone","desonide",0.776540453]
["clocortolone","desoximetasone",0.626224291]
["clocortolone","Halobetasol",0.863331695]
["clocortolone","flurandrenolone",0.852802865]
["isoflurane","succinylcholine",0.456009914]
["morphine","hydromorphone",0.431699784]
["morphine","oxycodone",0.490907482]
["troglitazone","rosiglitazone",0.434461127]
["lovastatin","pravastatin",0.663180417]
["lovastatin","simvastatin",0.821918075]
["lovastatin","cerivastatin",0.823094256]
["epitopic","loteprednol",0.470392293]
["pergolide","tiagabine",0.430145803]
["pergolide","glatiramer acetate",0.402583735]
["levobunolol","carteolol",0.670677832]
["fluticasone","mometasone",0.404880386]
["tazarotene","monobenzyl ether of hydroquinone",0.413023287]
["diflunisal","sulindac",0.543069575]
["secobarbital","phenobarbital",0.558035401]
["secobarbital","pentobarbital",1]
["secobarbital","mephobarbital",0.971422654]
["butoconazole","clotrimazole",0.488032944]
["mupirocin","malathion",0.50847518]
["mupirocin","butenafine",0.472192165]
["mupirocin","docosanol",0.40824829]
["alclometasone","fluocinonide",0.592441559]
["alclometasone","desonide",0.789376702]
["alclometasone","desoximetasone",0.636575807]
["alclometasone","Halobetasol",0.877602607]
["alclometasone","flurandrenolone",0.769023959]
["tropicamide","naphazoline",0.648885685]
["valganciclovir","ganciclovir",0.475703594]
["hydromorphone","oxycodone",0.540699282]
["zaleplon","nefazodone",0.401629045]
["zaleplon","mirtazapine",0.419327542]
["procaine","chloroprocaine",0.584567148]
["procaine","mepivacaine",0.567580524]
["procaine","tetracaine",0.45126086]
["betahistine","hydroquinone",0.43465076]
["betahistine","pinaverium bromide",0.429166254]
["pravastatin","simvastatin",0.671653082]
["pravastatin","cerivastatin",0.611560922]
["doxycycline","oxytetracycline",0.408448559]
["fluocinonide","desonide",0.541272643]
["fluocinonide","desoximetasone",0.433005662]
["fluocinonide","Halobetasol",0.592140514]
["fluocinonide","flurandrenolone",0.684783241]
["oxaprozin","etodolac",0.409866541]
["oxaprozin","piroxicam",0.548348718]
["dicyclomine","propantheline",0.470154166]
["cephalexin","cefadroxil",0.60930842]
["cephalexin","cefazolin",0.505412097]
["nadolol","propranolol",0.409403398]
["methylprednisolone","prednisolone",0.675244751]
["methylprednisolone","cortisol",0.756228221]
["methylprednisolone","triamcinolone",0.599380257]
["methylprednisolone","cortisone",0.713506068]
["methylprednisolone","dexamethasone",0.765746415]
["desonide","desoximetasone",0.636227447]
["desonide","Halobetasol",0.871535581]
["desonide","flurandrenolone",0.662235924]
["desoximetasone","Halobetasol",0.702831062]
["desoximetasone","flurandrenolone",0.53404587]
["desoximetasone","clobetasol",0.418477541]
["benzoyl","malathion",0.495918299]
["etodolac","piroxicam",0.484182026]
["hydroquinone","pinaverium bromide",0.481070235]
["thiazide","polythiazide",0.807726019]
["thiazide","hydroflumethiazide",0.807726019]
["thiazide","hydrochlorothiazide",0.430781465]
["thiazide","metolazone",0.437812443]
["melphalan","chlorambucil",0.429132563]
["chlorpheniramine","cyproheptadine",0.828488144]
["chlorpheniramine","carbinoxamine maleate",0.982141421]
["chlorpheniramine","diphenhydramine",0.90949762]
["amoxapine","nortriptyline",0.600850746]
["amoxapine","cyclobenzaprine",0.437466275]
["amoxapine","protriptyline",0.614130435]
["amoxapine","imipramine",0.615397028]
["sulfisoxazole","sulfasalazine",0.421388617]
["sulfisoxazole","sulfadiazine",0.64368464]
["gamma-aminobutyric acid","ascorbic acid",0.866025404]
["brimonidine","bimatoprost",0.419038244]
["prochlorperazine","thiothixene",0.539331536]
["prochlorperazine","perphenazine",0.600538502]
["prochlorperazine","chlorpromazine",0.785812199]
["prochlorperazine","fluphenazine",0.463167298]
["nortriptyline","cyclobenzaprine",0.52724973]
["nortriptyline","protriptyline",0.92459681]
["nortriptyline","imipramine",0.903500655]
["cyclobenzaprine","protriptyline",0.538243846]
["cyclobenzaprine","imipramine",0.5424913]
["simvastatin","cerivastatin",0.723900386]
["monobenzyl ether of hydroquinone","malathion",0.589661894]
["monobenzyl ether of hydroquinone","docosanol",0.400596372]
["sulfasalazine","sulfadiazine",0.550160382]
["iodine","iodixanol",0.443733058]
["polythiazide","hydroflumethiazide",1]
["polythiazide","metolazone",0.4144817]
["prednisolone","fluorometholone",0.451134337]
["prednisolone","cortisol",0.614362711]
["prednisolone","triamcinolone",0.522517092]
["prednisolone","cortisone",0.639542902]
["prednisolone","dexamethasone",0.640629256]
["polymyxin B sulfate","bacitracin A",0.5]
["tolazamide","glimepiride",0.466210518]
["tolazamide","glipizide",0.571110699]
["brinzolamide","lodoxamide",0.43971349]
["thiothixene","perphenazine",0.528822329]
["thiothixene","chlorpromazine",0.487230064]
["thiothixene","fluphenazine",0.428330116]
["perphenazine","chlorpromazine",0.580718862]
["perphenazine","fluphenazine",0.523478901]
["hydroflumethiazide","metolazone",0.4144817]
["Halobetasol","mometasone",0.43860808]
["Halobetasol","flurandrenolone",0.736251743]
["nitroglycerin","isosorbide dinitrate",0.494495245]
["chlorpromazine","fluphenazine",0.428401315]
["nefazodone","tiagabine",0.448535573]
["cortisol","triamcinolone",0.53584103]
["cortisol","cortisone",0.594828575]
["cortisol","dexamethasone",0.689558416]
["cefadroxil","cefixime",0.750228]
["cefadroxil","cefazolin",0.487617869]
["cyproheptadine","carbinoxamine maleate",0.846568988]
["cyproheptadine","diphenhydramine",0.776665451]
["propantheline","glycopyrrolate",0.437383525]
["cephem","cefixime",0.501966559]
["protriptyline","imipramine",0.900512165]
["prilocaine","mepivacaine",0.409457369]
["cefixime","cefazolin",0.420075]
["malathion","butenafine",0.468191092]
["malathion","cocaine",0.400066132]
["malathion","docosanol",0.622752369]
["penicillin V","ampicillin",0.517932397]
["phenobarbital","pentobarbital",0.558035401]
["phenobarbital","mephobarbital",0.54208823]
["demeclocycline","minocycline",0.531429695]
["demeclocycline","oxytetracycline",0.609229432]
["triamcinolone","cortisone",0.470496031]
["triamcinolone","dexamethasone",0.59689097]
["cortisone","dexamethasone",0.590547056]
["lamotrigine","tiagabine",0.408463949]
["lamivudine","zidovudine",0.428914855]
["minocycline","oxytetracycline",0.403528498]
["mepivacaine","bupivacaine",0.424040506]
["carbenicillin indanyl sodium","carbenicillin",1]
["penicillin","oxacillin",0.484456681]
["tiagabine","glatiramer acetate",0.411577541]
["ciclopirox","docosanol",0.419136822]
["pentobarbital","mephobarbital",0.971422654]
["methylene blue solution","ephedrine",0.430032953]
["carbinoxamine maleate","diphenhydramine",0.931266147]