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{"sheet":"Table S4 Trans-target genes of ","index":0,"n_rows":120,"n_cols":31,"rows_kept":120,"flags":["formulas_cached_only"]}
["LncRNA","LncRNA_position","Gene_id","Correlation","Energy","Position","Gene","NR:Seq-id","NR:Score","NR:Evalue","NR:Description","NT:Seq-id","NT:Score","NT:Evalue","NT:Description","Uniprot:UniProtKB-AC","Uniprot:Score","Uniprot:Evalue","Uniprot:Description","COG:gene","COG:Score","COG:Eval","COG:num","Pfam:pfam_ID","Pfam:pfam_Name","Pfam:pfam_Description","GO:biological_process","GO:cellular_component","GO:molecular_function","KEGG:KO","KEGG:Description"]
["MYH15.1","chr1:171573069-171730662:-","ZBED2",0.915711089,-64,"chr1:174544422-174553037:-","ZBED2","gi|802997305|ref|XP_012045522.1|",804,{"v":1e-93,"d":"1.00E-93"},"PREDICTED: zinc finger BED domain-containing protein 2 [Ovis aries]","gi|594101890|ref|XM_006073962.1|",3819,0,"PREDICTED: Bubalus bubalis zinc finger, BED-type containing 2 (ZBED2), mRNA","Q9BTP6",248,{"v":5e-72,"d":"5.00E-72"},"Zinc finger BED domain-containing protein 2",".",".",".",".","pfam02892","zf-BED","BED zinc finger.",".",".","GO:0003677|DNA binding;GO:0046872|metal ion binding;",".","."]
["MYH15.1","chr1:171573069-171730662:-","UNC13A",0.953721794,-64,"chr5:5176675-5216143:+","UNC13A","gi|803248433|ref|XP_011984192.1|",7324,0,"PREDICTED: protein unc-13 homolog A isoform X5 [Ovis aries musimon]","gi|594696736|ref|XM_007195485.1|",4773,0,"PREDICTED: Balaenoptera acutorostrata scammoni unc-13 homolog A (C. elegans) (UNC13A), transcript variant X2, mRNA","Q62768",2575,0,"Protein unc-13 homolog A",".",".",".",".","pfam10540","Membr_traf_MHD","Munc13 (mammalian uncoordinated) homology domain. Munc13 proteins constitute a family of three highly homologous molecules (Munc13-1, Munc13-2 and Munc13-3) with homology to Caenorhabditis elegans unc-13p. Munc13 proteins contain a phorbol ester-binding C1 domain and two C2 domains, which are Ca2+/phospholipid binding domains. Sequence analyses have uncovered two regions called Munc13 homology domains 1 (MHD1) and 2 (MHD2) that are arranged between two flanking C2 domains. MHD1 and MHD2 domains are present in a wide variety of proteins from Arabidopsis thaliana, C. elegans, Drosophila melanogaster, mouse, rat and human, some of which may function in a Munc13-like manner to regulate membrane trafficking. The MHD1 and MHD2 domains are predicted to be alpha-helical.","GO:0035556|intracellular signal transduction;GO:0060291|long-term synaptic potentiation;GO:0007269|neurotransmitter secretion;GO:0016082|synaptic vesicle priming;","GO:0030054|cell junction;GO:0005737|cytoplasm;GO:0060076|excitatory synapse;GO:0043005|neuron projection;GO:0042734|presynaptic membrane;GO:0043234|protein complex;GO:0043195|terminal bouton;","GO:0019992|diacylglycerol binding;GO:0046872|metal ion binding;GO:0019904|protein domain specific binding;GO:0046982|protein heterodimerization activity;GO:0042803|protein homodimerization activity;GO:0047485|protein N-terminus binding;GO:0000149|SNARE binding;GO:0030507|spectrin binding;GO:0017075|syntaxin-1 binding;","K15293","UNC13, MUNC13; protein unc-13"]
["MYH15.1","chr1:171573069-171730662:-","TRIM71",0.90719739,-64,"chr19:7122589-7189146:+","TRIM71","gi|803186865|ref|XP_011955702.1|",2684,0,"PREDICTED: LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM71 isoform X1, partial [Ovis aries]","gi|466057913|ref|XM_004279694.1|",1743,0,"PREDICTED: Orcinus orca tripartite motif containing 71, E3 ubiquitin protein ligase (TRIM71), mRNA","Q2Q1W2",93.6,{"v":2e-17,"d":"2.00E-17"},"E3 ubiquitin-protein ligase TRIM71",".",".",".",".","pfam00630","Filamin","Filamin/ABP280 repeat.","GO:0061158|3'-UTR-mediated mRNA destabilization;GO:0008543|fibroblast growth factor receptor signaling pathway;GO:0000082|G1/S transition of mitotic cell cycle;GO:0010586|miRNA metabolic process;GO:0017148|negative regulation of translation;GO:0035278|negative regulation of translation involved in gene silencing by miRNA;GO:0001843|neural tube closure;GO:0021915|neural tube development;GO:2000637|positive regulation of gene silencing by miRNA;GO:0051865|protein autoubiquitination;GO:0060964|regulation of gene silencing by miRNA;GO:2000177|regulation of neural precursor cell proliferation;GO:0072089|stem cell proliferation;","GO:0000932|cytoplasmic mRNA processing body;","GO:0016874|ligase activity;GO:0035198|miRNA binding;GO:0030371|translation repressor activity;GO:0061630|ubiquitin protein ligase activity;GO:0004842|ubiquitin-protein transferase activity;GO:0008270|zinc ion binding;","K12035","TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]"]
["MYH15.1","chr1:171573069-171730662:-","TPH1",0.957033866,-64,"chr15:33936711-33974002:+","TPH1","gi|528915277|ref|XP_005194645.1|",2342,0,"PREDICTED: tryptophan 5-hydroxylase 1 isoform X1 [Bos taurus]","gi|548495002|ref|XM_005689574.1|",3113,0,"PREDICTED: Capra hircus tryptophan hydroxylase 1 (TPH1), transcript variant X1, mRNA","P17752",874,0,"Tryptophan 5-hydroxylase 1","RSc3355",132,{"v":4e-32,"d":"4.00E-32"},"COG3186","pfam00351","Biopterin_H","Biopterin-dependent aromatic amino acid hydroxylase. This family includes phenylalanine-4-hydroxylase, the phenylketonuria disease protein.","GO:0009072|aromatic amino acid family metabolic process;GO:0046849|bone remodeling;GO:0034641|cellular nitrogen compound metabolic process;GO:0007623|circadian rhythm;GO:0046219|indolalkylamine biosynthetic process;GO:0060749|mammary gland alveolus development;GO:0030279|negative regulation of ossification;GO:0045600|positive regulation of fat cell differentiation;GO:0035902|response to immobilization stress;GO:0042427|serotonin biosynthetic process;GO:0044281|small molecule metabolic process;","GO:0005829|cytosol;GO:0043005|neuron projection;","GO:0016597|amino acid binding;GO:0005506|iron ion binding;GO:0004510|tryptophan 5-monooxygenase activity;","K00502","TPH1_2; tryptophan 5-monooxygenase [EC:1.14.16.4]"]
["MYH15.1","chr1:171573069-171730662:-","TP63",0.918038562,-64,"chr1:195514420-195783654:-","TP63","gi|823430605|ref|XP_004413020.2|",3587,0,"PREDICTED: tumor protein 63 isoform X1 [Odobenus rosmarus divergens]","gi|548450342|ref|XM_005675125.1|",4804,0,"PREDICTED: Capra hircus tumor protein p63 (TP63), transcript variant X1, mRNA","O88898",1128,0,"Tumor protein 63",".",".",".",".","pfam00870","P53","P53 DNA-binding domain. This family contains one anomalous member, viz: Zea mays (Q6JAD8). This sequence is identical to human P53 and would appear to be a a human contaminant within the Zea mays sampling effort.","GO:0048646|anatomical structure formation involved in morphogenesis;GO:0006915|apoptotic process;GO:0007569|cell aging;GO:0030154|cell differentiation;GO:0006974|cellular response to DNA damage stimulus;GO:0034644|cellular response to UV;GO:0006338|chromatin remodeling;GO:0060197|cloacal septation;GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0007499|ectoderm and mesoderm interaction;GO:0030326|embryonic limb morphogenesis;GO:0010481|epidermal cell division;GO:0008544|epidermis development;GO:0002064|epithelial cell development;GO:0030855|epithelial cell differentiation;GO:0001736|establishment of planar polarity;GO:0061436|establishment of skin barrier;GO:0048807|female genitalia morphogenesis;GO:0001942|hair follicle development;GO:0031069|hair follicle morphogenesis;GO:0042771|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0030216|keratinocyte differentiation;GO:0043616|keratinocyte proliferation;GO:0031571|mitotic G1 DNA damage checkpoint;GO:0001738|morphogenesis of a polarized epithelium;GO:0010259|multicellular organismal aging;GO:0007275|multicellular organismal development;GO:0043066|negative regulation of apoptotic process;GO:2000773|negative regulation of cellular senescence;GO:0045617|negative regulation of keratinocyte differentiation;GO:2000381|negative regulation of mesoderm development;GO:0000122|negative regulation of transcription from RNA polymerase II promoter;GO:0045892|negative regulation of transcription, DNA-templated;GO:0051402|neuron apoptotic process;GO:0007219|Notch signaling pathway;GO:0042475|odontogenesis of dentin-containing tooth;GO:0009887|organ morphogenesis;GO:0007389|pattern specification process;GO:0030859|polarized epithelial cell differentiation;GO:2001235|positive regulation of apoptotic signaling pathway;GO:1902808|positive regulation of cell cycle G1/S phase transition;GO:2000271|positive regulation of fibroblast apoptotic process;GO:0010838|positive regulation of keratinocyte proliferation;GO:0002053|positive regulation of mesenchymal cell proliferation;GO:0045747|positive regulation of Notch signaling pathway;GO:0045669|positive regulation of osteoblast differentiation;GO:0045944|positive regulation of transcription from RNA polymerase II promoter;GO:0045893|positive regulation of transcription, DNA-templated;GO:0036342|post-anal tail morphogenesis;GO:0030850|prostate gland development;GO:0060513|prostatic bud formation;GO:0051289|protein homotetramerization;GO:0009954|proximal/distal pattern formation;GO:0043281|regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0010482|regulation of epidermal cell division;GO:0043523|regulation of neuron apoptotic process;GO:0001302|replicative cell aging;GO:0010332|response to gamma radiation;GO:0010165|response to X-ray;GO:0001501|skeletal system development;GO:0043589|skin morphogenesis;GO:0048745|smooth muscle tissue development;GO:0007283|spermatogenesis;GO:0060529|squamous basal epithelial stem cell differentiation involved in prostate gland acinus development;GO:0048485|sympathetic nervous system development;GO:0006366|transcription from RNA polymerase II promoter;GO:0060157|urinary bladder development;","GO:0000785|chromatin;GO:0005737|cytoplasm;GO:0005829|cytosol;GO:0030425|dendrite;GO:0000790|nuclear chromatin;GO:0005654|nucleoplasm;GO:0005634|nucleus;GO:0005791|rough endoplasmic reticulum;GO:0005667|transcription factor complex;","GO:0003682|chromatin binding;GO:0003684|damaged DNA binding;GO:0003677|DNA binding;GO:0003690|double-stranded DNA binding;GO:0042802|identical protein binding;GO:0046872|metal ion binding;GO:0002039|p53 binding;GO:0001077|transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding;GO:0043565|sequence-specific DNA binding;GO:0000989|transcription factor activity, transcription factor binding;GO:0044212|transcription regulatory region DNA binding;GO:0050699|WW domain binding;","K10149","TP63; tumor protein p63"]
["MYH15.1","chr1:171573069-171730662:-","TMC3",0.931160934,-64,"chr18:26143686-26199298:-","TMC3","gi|426248190|ref|XP_004017848.1|",5569,0,"PREDICTED: transmembrane channel-like protein 3 [Ovis aries]","gi|594104963|ref|XM_006075388.1|",3352,0,"PREDICTED: Bubalus bubalis transmembrane channel-like 3 (TMC3), mRNA","Q7Z5M5",1737,0,"Transmembrane channel-like protein 3",".",".",".",".","pfam07810","TMC","TMC domain. These sequences are similar to a region conserved amongst various protein products of the transmembrane channel-like (TMC) gene family, such as Transmembrane channel-like protein 3 and EVIN2 - this region is termed the TMC domain. Mutations in these genes are implicated in a number of human conditions, such as deafness and epidermodysplasia verruciformis. TMC proteins are thought to have important cellular roles, and may be modifiers of ion channels or transporters.","GO:0006811|ion transport;","GO:0016021|integral component of membrane;",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","TLR9",0.919911828,-64,"chr19:48652597-48657136:+","TLR9","gi|58531203|ref|NP_001011555.1|",3196,0,"toll-like receptor 9 precursor [Ovis aries]","gi|289488966|gb|GU451250.1|",1461,0,"Ovis aries voucher 1496 breed Tsigai toll-like receptor 9 (TLR9) gene, partial cds","Q5I2M4",281,{"v":5e-78,"d":"5.00E-78"},"Toll-like receptor 9","ECU09g0200",52,6e-06,"COG4886","pfam13855","LRR_8","Leucine rich repeat.","GO:0006954|inflammatory response;GO:0045087|innate immune response;GO:0002755|MyD88-dependent toll-like receptor signaling pathway;GO:0050729|positive regulation of inflammatory response;GO:0045356|positive regulation of interferon-alpha biosynthetic process;GO:0045359|positive regulation of interferon-beta biosynthetic process;GO:0045078|positive regulation of interferon-gamma biosynthetic process;GO:0050707|regulation of cytokine secretion;GO:0002237|response to molecule of bacterial origin;GO:0034162|toll-like receptor 9 signaling pathway;","GO:0032009|early phagosome;GO:0005783|endoplasmic reticulum;GO:0005789|endoplasmic reticulum membrane;GO:0005768|endosome;GO:0016021|integral component of membrane;GO:0005764|lysosome;","GO:0035197|siRNA binding;GO:0004888|transmembrane signaling receptor activity;","K10161","TLR9; toll-like receptor 9"]
["MYH15.1","chr1:171573069-171730662:-","TEKT5",0.916501836,-64,"chr24:9360539-9409219:-","TEKT5","gi|426254298|ref|XP_004020816.1|",2540,0,"PREDICTED: tektin-5 [Ovis aries]","gi|556779302|ref|XM_005984644.1|",1585,0,"PREDICTED: Pantholops hodgsonii tektin 5 (TEKT5), mRNA","Q2YDI7",962,0,"Tektin-5",".",".",".",".","pfam03148","Tektin","Tektin family. Tektins are cytoskeletal proteins. They have been demonstrated in such cellular sites as centrioles, basal bodies, and along ciliary and flagellar doublet microtubules. Tektins form unique protofilaments, organized as longitudinal polymers of tektin heterodimers with axial periodicity matching tubulin. Tektin polypeptides consist of several alpha-helical regions that are predicted to form coiled coils. Indeed, tektins share considerable structural similarities with intermediate filament proteins. Possible functional roles for tektins are: stabilisation of tubulin protofilaments; attachment of A and B-tubules in ciliary/flagellar microtubule doublets and C-tubules in centrioles; binding of axonemal components.",".","GO:0005929|cilium;GO:0005737|cytoplasm;GO:0005874|microtubule;",".","K18632","TEKT5; tektin-5"]
["MYH15.1","chr1:171573069-171730662:-","TDO2",0.95864403,-64,"chr17:43034811-43052325:-","TDO2","gi|426247133|ref|XP_004017341.1|",1985,0,"PREDICTED: tryptophan 2,3-dioxygenase isoform X1 [Ovis aries]","gi|594110875|ref|XM_006078212.1|",2004,0,"PREDICTED: Bubalus bubalis tryptophan 2,3-dioxygenase (TDO2), mRNA","Q2KIQ5",753,0,"Tryptophan 2,3-dioxygenase","RSp0694",136,{"v":8e-34,"d":"8.00E-34"},"COG3483","pfam03301","Trp_dioxygenase","Tryptophan 2,3-dioxygenase.","GO:0019442|tryptophan catabolic process to acetyl-CoA;GO:0019441|tryptophan catabolic process to kynurenine;",".","GO:0020037|heme binding;GO:0046872|metal ion binding;GO:0004833|tryptophan 2,3-dioxygenase activity;","K00453","E1.13.11.11, TDO2; tryptophan 2,3-dioxygenase [EC:1.13.11.11]"]
["MYH15","chr1:171569543-171575119:+","SV2A",0.909773066,-64,"chr1:98791186-98801671:-","SV2A","gi|291398069|ref|XP_002715673.1|",3269,0,"PREDICTED: synaptic vesicle glycoprotein 2A [Oryctolagus cuniculus]","gi|556750777|ref|XM_005970740.1|",4043,0,"PREDICTED: Pantholops hodgsonii synaptic vesicle glycoprotein 2A (SV2A), mRNA","Q7L0J3",1242,0,"Synaptic vesicle glycoprotein 2A",".",".",".",".","pfam00083","Sugar_tr","Sugar (and other) transporter.","GO:0006874|cellular calcium ion homeostasis;GO:0006836|neurotransmitter transport;","GO:0005911|cell-cell junction;GO:0005737|cytoplasm;GO:0005783|endoplasmic reticulum;GO:0016021|integral component of membrane;GO:0031594|neuromuscular junction;GO:0005886|plasma membrane;GO:0048786|presynaptic active zone;GO:0008021|synaptic vesicle;GO:0030672|synaptic vesicle membrane;GO:0043195|terminal bouton;","GO:0019901|protein kinase binding;GO:0004872|receptor activity;GO:0022857|transmembrane transporter activity;","K06258","SV2; MFS transporter, VNT family, synaptic vesicle glycoprotein 2"]
["MYH15.1","chr1:171573069-171730662:-","SPATC1",0.927145068,-64,"chr9:13664308-13693877:-","SPATC1","gi|803104040|ref|XP_012038840.1|",2080,0,"PREDICTED: speriolin isoform X2 [Ovis aries]","gi|594032748|ref|XM_006041070.1|",2090,0,"PREDICTED: Bubalus bubalis spermatogenesis and centriole associated 1 (SPATC1), mRNA","Q148B6",508,{"v":1e-162,"d":"1.00E-162"},"Speriolin",".",".",".",".","pfam15059","Speriolin_C","Speriolin C-terminus. This family represents the C-terminus of the sperm centrosome protein speriolin.",".","GO:0005813|centrosome;GO:0005737|cytoplasm;",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","SMYD1",0.93959096,-64,"chr3:58491015-58537526:+","SMYD1","gi|426223567|ref|XP_004005946.1|",2670,0,"PREDICTED: histone-lysine N-methyltransferase SMYD1 isoform X1 [Ovis aries]","gi|134085964|ref|NM_001083484.1|",4489,0,"Bos taurus SET and MYND domain containing 1 (SMYD1), mRNA","Q8NB12",961,0,"Histone-lysine N-methyltransferase SMYD1","SPBP8B7.07c",90.1,{"v":2e-17,"d":"2.00E-17"},"COG2940","pfam01753","zf-MYND","MYND finger.","GO:0006338|chromatin remodeling;GO:0007507|heart development;GO:0045892|negative regulation of transcription, DNA-templated;GO:0045663|positive regulation of myoblast differentiation;GO:0010831|positive regulation of myotube differentiation;GO:0035914|skeletal muscle cell differentiation;GO:0006351|transcription, DNA-templated;","GO:0005737|cytoplasm;GO:0005634|nucleus;","GO:0003677|DNA binding;GO:0018024|histone-lysine N-methyltransferase activity;GO:0046872|metal ion binding;GO:0003714|transcription corepressor activity;","K11426","SMYD; SET and MYND domain-containing protein"]
["NYAP1","chr24:35900853-35960797:-","SMARCD2",0.900521299,-64,"chr11:47450026-47459562:-","SMARCD2","gi|803252946|ref|XP_011986426.1|",2235,0,"PREDICTED: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 isoform X2 [Ovis aries musimon]","gi|594033944|ref|XM_006041628.1|",2484,0,"PREDICTED: Bubalus bubalis SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 (SMARCD2), mRNA","E1BJD1",858,0,"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2","SPAC23G3.10c",223,{"v":3e-63,"d":"3.00E-63"},"COG5531","pfam02201","SWIB","SWIB/MDM2 domain. This family includes the SWIB domain and the MDM2 domain. The p53-associated protein (MDM2) is an inhibitor of the p53 tumor suppressor gene binding the transactivation domain and down regulating the ability of p53 to activate transcription. This family contains the p53 binding domain of MDM2.","GO:0043044|ATP-dependent chromatin remodeling;GO:0006337|nucleosome disassembly;GO:0006355|regulation of transcription, DNA-templated;GO:0006351|transcription, DNA-templated;","GO:0000790|nuclear chromatin;GO:0016514|SWI/SNF complex;","GO:0000978|RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000980|RNA polymerase II distal enhancer sequence-specific DNA binding;","K11650","SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D"]
["MYH15.1","chr1:171573069-171730662:-","SLCO1A2",0.91574563,-64,"chr3:193316539-193433818:+","SLCO1A2","gi|426225390|ref|XP_004006849.1|",3366,0,"PREDICTED: solute carrier organic anion transporter family member 1A2 isoform X1 [Ovis aries]","gi|31341430|ref|NM_174654.2|",2440,0,"Bos taurus solute carrier organic anion transporter family, member 1A2 (SLCO1A2), mRNA","P46721",1058,0,"Solute carrier organic anion transporter family member 1A2",".",".",".",".","pfam03137","OATP","Organic Anion Transporter Polypeptide (OATP) family. This family consists of several eukaryotic Organic-Anion-Transporting Polypeptides (OATPs). Several have been identified mostly in human and rat. Different OATPs vary in tissue distribution and substrate specificity. Since the numbering of different OATPs in particular species was based originally on the order of discovery, similarly numbered OATPs in humans and rats did not necessarily correspond in function, tissue distribution and substrate specificity (in spite of the name, some OATPs also transport organic cations and neutral molecules). Thus, Tamai et al. initiated the current scheme of using digits for rat OATPs and letters for human ones. Prostaglandin transporter (PGT) proteins are also considered to be OATP family members. In addition, the methotrexate transporter OATK is closely related to OATPs. This family also includes several predicted proteins from Caenorhabditis elegans and Drosophila melanogaster. This similarity was not previously noted. Note: Members of this family are described (in the Swiss-Prot database) as belonging to the SLC21 family of transporters.","GO:0098779|mitophagy in response to mitochondrial depolarization;GO:0015721|bile acid and bile salt transport;GO:0008206|bile acid metabolic process;GO:0015711|organic anion transport;GO:0044281|small molecule metabolic process;GO:0043252|sodium-independent organic anion transport;GO:0055085|transmembrane transport;","GO:0016021|integral component of membrane;GO:0005886|plasma membrane;","GO:0008514|organic anion transmembrane transporter activity;","K03460","SLCO1A; solute carrier organic anion transporter family, member 1A"]
["MYH15.1","chr1:171573069-171730662:-","SLC7A13",0.903561161,-64,"chr9:88953277-88964729:+","SLC7A13","gi|803106845|ref|XP_012039569.1|",1273,{"v":2e-173,"d":"2.00E-173"},"PREDICTED: LOW QUALITY PROTEIN: solute carrier family 7 member 13 isoform X1 [Ovis aries]","gi|548493976|ref|XM_005709741.1|",659,0,"PREDICTED: Capra hircus solute carrier family 7 (anionic amino acid transporter), member 13 (SLC7A13), mRNA","Q8TCU3",259,{"v":3e-80,"d":"3.00E-80"},"Solute carrier family 7 member 13",".",".",".",".","pfam13520","AA_permease_2","Amino acid permease.","GO:0003333|amino acid transmembrane transport;GO:1902475|L-alpha-amino acid transmembrane transport;GO:0015807|L-amino acid transport;","GO:0005887|integral component of plasma membrane;","GO:0015297|antiporter activity;GO:0015179|L-amino acid transmembrane transporter activity;","K13870","SLC7A13, AGT1; solute carrier family 7 (L-type amino acid transporter), member 13"]
["MYH15.1","chr1:171573069-171730662:-","SLC39A12",0.977707642,-64,"chr13:31428867-31510994:+","SLC39A12","gi|426240835|ref|XP_004014299.1|",3279,0,"PREDICTED: zinc transporter ZIP12 isoform X1 [Ovis aries]","gi|594106111|ref|XM_006075928.1|",2512,0,"PREDICTED: Bubalus bubalis solute carrier family 39 (zinc transporter), member 12 (SLC39A12), transcript variant X2, mRNA","Q08E40",1144,0,"Zinc transporter ZIP12","RSc2227",94.4,{"v":6e-20,"d":"6.00E-20"},"COG0428","pfam02535","Zip","ZIP Zinc transporter. The ZIP family consists of zinc transport proteins and many putative metal transporters. The main contribution to this family is from the Arabidopsis thaliana ZIP protein family these proteins are responsible for zinc uptake in the plant. Also found within this family are C. elegans proteins of unknown function which are annotated as being similar to human growth arrest inducible gene product, although this protein in not found within this family.","GO:0031113|regulation of microtubule polymerization;GO:0010975|regulation of neuron projection development;GO:0007165|signal transduction;GO:0071578|zinc II ion transmembrane import;","GO:0016021|integral component of membrane;GO:0048471|perinuclear region of cytoplasm;GO:0005886|plasma membrane;GO:0031982|vesicle;","GO:0005385|zinc ion transmembrane transporter activity;","K14718","SLC39A12, ZIP12; solute carrier family 39 (zinc transporter), member 12"]
["MYH15.1","chr1:171573069-171730662:-","SLC17A1",0.907928474,-64,"chr20:30837703-30889327:+","SLC17A1","gi|741900553|ref|XP_010823743.1|",2202,0,"PREDICTED: sodium-dependent phosphate transport protein 1 isoform X2 [Bos taurus]","gi|548518331|ref|XM_005696767.1|",1723,0,"PREDICTED: Capra hircus solute carrier family 17 (organic anion transporter), member 1 (SLC17A1), mRNA","Q28722",55.8,5e-07,"Sodium-dependent phosphate transport protein 1",".",".",".",".","pfam07690","MFS_1","Major Facilitator Superfamily.","GO:0006814|sodium ion transport;","GO:0016021|integral component of membrane;","GO:0015114|phosphate ion transmembrane transporter activity;GO:0015293|symporter activity;","K12300","SLC17A1S; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 1/2/3/4"]
["MYH15.1","chr1:171573069-171730662:-","RTL1",0.922397882,-64,"chr18:64382318-64406185:-","RTL1","gi|426248579|ref|XP_004018040.1|",5924,0,"PREDICTED: retrotransposon-like protein 1 [Ovis aries]","gi|594112752|ref|XM_006079091.1|",4090,0,"PREDICTED: Bubalus bubalis retrotransposon-like 1 (RTL1), mRNA","Q52QI2",2117,0,"Retrotransposon-like protein 1","SPAC9.04",118,{"v":9e-26,"d":"9.00E-26"},"COG2801","pfam03732","Retrotrans_gag","Retrotransposon gag protein. Gag or Capsid-like proteins from LTR retrotransposons. There is a central motif QGXXEXXXXXFXXLXXH that is common to Retroviridae gag-proteins, but is poorly conserved.","GO:0007275|multicellular organismal development;","GO:0016021|integral component of membrane;",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","PROM2",0.967905108,-64,"chr3:104204224-104218895:-","PROM2","gi|803041461|ref|XP_012029249.1|",3237,0,"PREDICTED: prominin-2 isoform X1 [Ovis aries]","gi|548484794|ref|XM_005686245.1|",3627,0,"PREDICTED: Capra hircus prominin 2 (PROM2), mRNA","Q8N271",968,0,"Prominin-2",".",".",".",".","pfam05478","Prominin","Prominin. The prominins are an emerging family of proteins that among the multispan membrane proteins display a novel topology. Mouse prominin and human prominin (mouse)-like 1 (PROML1) are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain. The exact function of prominin is unknown although in humans defects in PROM1, the gene coding for prominin, cause retinal degeneration.","GO:2001287|negative regulation of caveolin-mediated endocytosis;GO:0048550|negative regulation of pinocytosis;GO:0031346|positive regulation of cell projection organization;GO:0001934|positive regulation of protein phosphorylation;GO:0043087|regulation of GTPase activity;","GO:0016324|apical plasma membrane;GO:0016323|basolateral plasma membrane;GO:0042995|cell projection;GO:0009986|cell surface;GO:0060170|ciliary membrane;GO:0005929|cilium;GO:0031410|cytoplasmic vesicle;GO:0070062|extracellular exosome;GO:0005887|integral component of plasma membrane;GO:0044393|microspike;GO:0005902|microvillus;GO:0031528|microvillus membrane;GO:0071914|prominosome;","GO:0015485|cholesterol binding;","K15602","PROM2; prominin 2"]
["MYH15.1","chr1:171573069-171730662:-","PIPOX",0.929459958,-64,"chr11:19994775-20008065:+","PIPOX","gi|803119265|ref|XP_012040801.1|",2080,0,"PREDICTED: peroxisomal sarcosine oxidase isoform X1 [Ovis aries]","gi|556723378|ref|XM_005957449.1|",2255,0,"PREDICTED: Pantholops hodgsonii pipecolic acid oxidase (PIPOX), mRNA","Q29RU9",683,0,"Peroxisomal sarcosine oxidase","STM1160",109,{"v":1e-32,"d":"1.00E-32"},"COG0665","pfam01266","DAO","FAD dependent oxidoreductase. This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.","GO:0033514|L-lysine catabolic process to acetyl-CoA via L-pipecolate;GO:0046653|tetrahydrofolate metabolic process;","GO:0005777|peroxisome;","GO:0050031|L-pipecolate oxidase activity;GO:0008115|sarcosine oxidase activity;","K00306","PIPOX; sarcosine oxidase / L-pipecolate oxidase [EC:1.5.3.1 1.5.3.7]"]
["MYH15.1","chr1:171573069-171730662:-","PEX5L",0.912071012,-64,"chr1:205083187-205364186:+","PEX5L","gi|829987615|ref|XP_004675052.2|",3182,0,"PREDICTED: PEX5-related protein isoform X2 [Condylura cristata]","gi|548451076|ref|XM_005675270.1|",2675,0,"PREDICTED: Capra hircus peroxisomal biogenesis factor 5-like (PEX5L), transcript variant X1, mRNA","Q8IYB4",1062,0,"PEX5-related protein",".",".",".",".","pfam13414","TPR_11","TPR repeat.","GO:0045185|maintenance of protein location;GO:0016560|protein import into peroxisome matrix, docking;GO:0043949|regulation of cAMP-mediated signaling;GO:0042391|regulation of membrane potential;","GO:0005829|cytosol;GO:0030425|dendrite;GO:0005778|peroxisomal membrane;GO:0043235|receptor complex;","GO:0005052|peroxisome matrix targeting signal-1 binding;GO:0000268|peroxisome targeting sequence binding;GO:0031267|small GTPase binding;",".","."]
["NYAP1","chr24:35900853-35960797:-","PELP1",0.925313193,-64,"chr11:26203266-26253240:+","PELP1","gi|803235979|ref|XP_011978126.1|",2960,0,"PREDICTED: proline-, glutamic acid- and leucine-rich protein 1 isoform X2 [Ovis aries musimon]","gi|555988533|ref|XM_005906044.1|",2349,0,"PREDICTED: Bos mutus proline, glutamate and leucine rich protein 1 (PELP1), transcript variant X1, mRNA","Q8IZL8",106,{"v":1e-21,"d":"1.00E-21"},"Proline-, glutamic acid- and leucine-rich protein 1",".",".",".",".","pfam08166","NUC202","NUC202 domain. This domain is found in a novel family of nucleolar proteins.","GO:0071391|cellular response to estrogen stimulus;GO:0045944|positive regulation of transcription from RNA polymerase II promoter;GO:0006351|transcription, DNA-templated;","GO:0005737|cytoplasm;GO:0016020|membrane;GO:0071339|MLL1 complex;GO:0005730|nucleolus;GO:0005654|nucleoplasm;GO:0005634|nucleus;GO:0035327|transcriptionally active chromatin;","GO:0003682|chromatin binding;GO:0044822|poly(A) RNA binding;GO:0008134|transcription factor binding;","K16913","PELP1, MNAR; proline-, glutamic acid- and leucine-rich protein 1"]
["NR0B1","chrx:27539342-27553262:-","PAFAH1B3",0.912283828,-64,"chr14:49926465-49929241:+","PAFAH1B3","gi|803147321|ref|XP_004015754.2|",1088,{"v":4e-147,"d":"4.00E-147"},"PREDICTED: platelet-activating factor acetylhydrolase IB subunit gamma isoform X1 [Ovis aries]","gi|548504704|ref|XM_005692565.1|",681,0,"PREDICTED: Capra hircus platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) (PAFAH1B3), transcript variant X1, mRNA","Q29460",420,{"v":9e-148,"d":"9.00E-148"},"Platelet-activating factor acetylhydrolase IB subunit gamma","all0976",53.5,1e-07,"COG2755","pfam13472","Lipase_GDSL_2","GDSL-like Lipase/Acylhydrolase family. This family of presumed lipases and related enzymes are similar to pfam00657.","GO:0007420|brain development;GO:0016042|lipid catabolic process;GO:0007283|spermatogenesis;","GO:0005737|cytoplasm;GO:0070062|extracellular exosome;GO:0016020|membrane;","GO:0003847|1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0047179|platelet-activating factor acetyltransferase activity;","K16795","PAFAH1B2_3; platelet-activating factor acetylhydrolase IB subunit beta/gamma [EC:3.1.1.47]"]
["MYH15.1","chr1:171573069-171730662:-","OC90",0.907283351,-64,"chr9:22006358-22031748:+","OC90","gi|803107563|ref|XP_012039657.1|",2802,0,"PREDICTED: otoconin-90 isoform X1 [Ovis aries]","gi|548492577|ref|XM_005688939.1|",1220,0,"PREDICTED: Capra hircus otoconin 90 (OC90), mRNA","Q02509",669,0,"Otoconin-90",".",".",".",".","pfam00068","Phospholip_A2_1","Phospholipase A2. Phospholipase A2 releases fatty acids from the second carbon group of glycerol. Perhaps the best known members are secreted snake venoms, but also found in secreted pancreatic and membrane-associated forms. Structure is all-alpha, with two core disulfide-linked helices and a calcium-binding loop. This alignment represents the major family of PLA2s. A second minor family, defined by the honeybee venom PLA2 PDB:1POC and related sequences from Gila monsters (Heloderma), is not recognized. This minor family conserves the core helix pair but is substantially different elsewhere. The PROSITE pattern PA2_HIS, specific to the first core helix, recognizes both families.","GO:0016042|lipid catabolic process;GO:0006644|phospholipid metabolic process;","GO:0005576|extracellular region;","GO:0005509|calcium ion binding;GO:0004623|phospholipase A2 activity;",".","."]
["MYH15.1","chr1:171573069-171730662:-","MYOM2",0.936715886,-64,"chr26:1172075-1236128:+","MYOM2","gi|426256494|ref|XP_004021875.1|",7565,0,"PREDICTED: myomesin-2 isoform X1 [Ovis aries]","gi|556721158|ref|XM_005956374.1|",4235,0,"PREDICTED: Pantholops hodgsonii myomesin 2 (MYOM2), mRNA","P54296",2580,0,"Myomesin-2",".",".",".",".","pfam07679","I-set","Immunoglobulin I-set domain.","GO:0006936|muscle contraction;","GO:0031430|M band;GO:0005739|mitochondrion;GO:0032982|myosin filament;","GO:0008307|structural constituent of muscle;",".","."]
["MYH15.1","chr1:171573069-171730662:-","MSGN1",0.935835827,-64,"chr3:25717492-25718067:+","MSGN1","gi|426223168|ref|XP_004005749.1|",667,{"v":1e-85,"d":"1.00E-85"},"PREDICTED: mesogenin-1 [Ovis aries]","gi|548486660|ref|XM_005686983.1|",552,0,"PREDICTED: Capra hircus mesogenin 1 (MSGN1), mRNA","A6NI15",209,{"v":7e-67,"d":"7.00E-67"},"Mesogenin-1",".",".",".",".","pfam00010","HLH","Helix-loop-helix DNA-binding domain.","GO:0030154|cell differentiation;GO:0007379|segment specification;GO:0001756|somitogenesis;","GO:0005634|nucleus;","GO:0003682|chromatin binding;GO:0003677|DNA binding;GO:0001228|transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding;","K09077","MSGN1; mesogenin 1"]
["MYH15.1","chr1:171573069-171730662:-","MOG",0.962790085,-64,"chr20:27895319-27908305:-","MOG","gi|426250670|ref|XP_004019057.1|",1090,{"v":2e-135,"d":"2.00E-135"},"PREDICTED: myelin-oligodendrocyte glycoprotein isoform X2 [Ovis aries]","gi|507833876|emb|FQ482095.2|",2511,0,"B.taurus DNA sequence from clone CH240-165A9, complete sequence","P55803",321,{"v":4e-99,"d":"4.00E-99"},"Myelin-oligodendrocyte glycoprotein",".",".",".",".","pfam07679","I-set","Immunoglobulin I-set domain.","GO:0007155|cell adhesion;","GO:0016021|integral component of membrane;",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","MMP20",0.942018992,-64,"chr15:5593138-5656126:+","MMP20","gi|426244423|ref|XP_004016022.1|",2511,0,"PREDICTED: matrix metalloproteinase-20 [Ovis aries]","gi|548494067|ref|XM_005689365.1|",2036,0,"PREDICTED: Capra hircus matrix metallopeptidase 20 (MMP20), mRNA","O18767",943,0,"Matrix metalloproteinase-20",".",".",".",".","pfam00413","Peptidase_M10","Matrixin. The members of this family are enzymes that cleave peptides. These proteases require zinc for catalysis.",".","GO:0005578|proteinaceous extracellular matrix;","GO:0005509|calcium ion binding;GO:0004222|metalloendopeptidase activity;GO:0008270|zinc ion binding;","K07999","MMP20; matrix metalloproteinase-20 (enamelysin) [EC:3.4.24.-]"]
["MYH15.1","chr1:171573069-171730662:-","MLNR",0.94682177,-64,"chr10:19161212-19163502:+","MLNR","gi|426236721|ref|XP_004012316.1|",1396,0,"PREDICTED: motilin receptor isoform X1 [Ovis aries]","gi|556768024|ref|XM_005979178.1|",546,0,"PREDICTED: Pantholops hodgsonii motilin receptor (MLNR), partial mRNA","O43193",243,{"v":2e-74,"d":"2.00E-74"},"Motilin receptor",".",".",".",".","pfam00001","7tm_1","7 transmembrane receptor (rhodopsin family). This family contains, amongst other G-protein-coupled receptors (GCPRs), members of the opsin family, which have been considered to be typical members of the rhodopsin superfamily. They share several motifs, mainly the seven transmembrane helices, GCPRs of the rhodopsin superfamily. All opsins bind a chromophore, such as 11-cis-retinal. The function of most opsins other than the photoisomerases is split into two steps: light absorption and G-protein activation. Photoisomerases, on the other hand, are not coupled to G-proteins - they are thought to generate and supply the chromophore that is used by visual opsins.","GO:0007586|digestion;GO:0007186|G-protein coupled receptor signaling pathway;","GO:0005887|integral component of plasma membrane;GO:0005886|plasma membrane;","GO:0004930|G-protein coupled receptor activity;GO:0016520|growth hormone-releasing hormone receptor activity;","K05266","MLNR; motilin receptor"]
["MYH15","chr1:171569543-171575119:+","LSS",0.932156379,-64,"chr1:263836789-263868476:-","LSS","gi|803006013|ref|XP_011960045.1|",3893,0,"PREDICTED: lanosterol synthase isoform X1 [Ovis aries]","gi|556776807|ref|XM_005983439.1|",3836,0,"PREDICTED: Pantholops hodgsonii lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (LSS), transcript variant X1, mRNA","P84466",1431,0,"Lanosterol synthase","YHR072w",520,{"v":5e-165,"d":"5.00E-165"},"COG1657","pfam13249","Prenyltrans_2","Prenyltransferase-like.","GO:0006694|steroid biosynthetic process;","GO:0005789|endoplasmic reticulum membrane;","GO:0000250|lanosterol synthase activity;","K01852","E5.4.99.7, LSS, ERG7; lanosterol synthase [EC:5.4.99.7]"]
["MYH15.1","chr1:171573069-171730662:-","LOC101121796",0.901665466,-64,"chr14:49302918-49328850:-","LOC101121796","gi|742162124|ref|XP_010847559.1|",785,{"v":1e-180,"d":"1.00E-180"},"PREDICTED: cytochrome P450 2B4-like [Bison bison bison]","gi|556735985|ref|XM_005963534.1|",817,0,"PREDICTED: Pantholops hodgsonii cytochrome P450 2B4-like (LOC102326876), mRNA","O55071",201,{"v":1e-125,"d":"1.00E-125"},"Cytochrome P450 2B19","alr1450",58.2,{"v":6e-10,"d":"6.00E-10"},"COG2124","pfam00067","p450","Cytochrome P450. Cytochrome P450s are haem-thiolate proteins involved in the oxidative degradation of various compounds. They are particularly well known for their role in the degradation of environmental toxins and mutagens. They can be divided into 4 classes, according to the method by which electrons from NAD(P)H are delivered to the catalytic site. Sequence conservation is relatively low within the family - there are only 3 absolutely conserved residues - but their general topography and structural fold are highly conserved. The conserved core is composed of a coil termed the 'meander', a four-helix bundle, helices J and K, and two sets of beta-sheets. These constitute the haem-binding loop (with an absolutely conserved cysteine that serves as the 5th ligand for the haem iron), the proton-transfer groove and the absolutely conserved EXXR motif in helix K. While prokaryotic P450s are soluble proteins, most eukaryotic P450s are associated with microsomal membranes. their general enzymatic function is to catalyse regiospecific and stereospecific oxidation of non-activated hydrocarbons at physiological temperatures.","GO:0019373|epoxygenase P450 pathway;GO:0042738|exogenous drug catabolic process;GO:0055114|oxidation-reduction process;GO:0006805|xenobiotic metabolic process;","GO:0005737|cytoplasm;GO:0005789|endoplasmic reticulum membrane;GO:0043231|intracellular membrane-bounded organelle;","GO:0008392|arachidonic acid epoxygenase activity;GO:0070330|aromatase activity;GO:0020037|heme binding;GO:0005506|iron ion binding;GO:0016712|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0019825|oxygen binding;GO:0008395|steroid hydroxylase activity;","K07412","CYP2B; cytochrome P450, family 2, subfamily B [EC:1.14.14.1]"]
["MYH15.1","chr1:171573069-171730662:-","LOC101121539",0.906108898,-64,"chr14:49109046-49120408:-","LOC101121539","gi|803152998|ref|XP_011950446.1|",2668,0,"PREDICTED: cytochrome P450 2F3 isoform X1 [Ovis aries]","gi|548504254|ref|XM_005692427.1|",1568,0,"PREDICTED: Capra hircus cytochrome P450 2F3-like (LOC102191547), transcript variant X2, mRNA","O18809",944,0,"Cytochrome P450 2F3","all3746",117,{"v":3e-27,"d":"3.00E-27"},"COG2124","pfam00067","p450","Cytochrome P450. Cytochrome P450s are haem-thiolate proteins involved in the oxidative degradation of various compounds. They are particularly well known for their role in the degradation of environmental toxins and mutagens. They can be divided into 4 classes, according to the method by which electrons from NAD(P)H are delivered to the catalytic site. Sequence conservation is relatively low within the family - there are only 3 absolutely conserved residues - but their general topography and structural fold are highly conserved. The conserved core is composed of a coil termed the 'meander', a four-helix bundle, helices J and K, and two sets of beta-sheets. These constitute the haem-binding loop (with an absolutely conserved cysteine that serves as the 5th ligand for the haem iron), the proton-transfer groove and the absolutely conserved EXXR motif in helix K. While prokaryotic P450s are soluble proteins, most eukaryotic P450s are associated with microsomal membranes. their general enzymatic function is to catalyse regiospecific and stereospecific oxidation of non-activated hydrocarbons at physiological temperatures.",".","GO:0005789|endoplasmic reticulum membrane;","GO:0070330|aromatase activity;GO:0020037|heme binding;GO:0005506|iron ion binding;GO:0019825|oxygen binding;","K07416","CYP2F; cytochrome P450, family 2, subfamily F [EC:1.14.14.1]"]
["MYH15.1","chr1:171573069-171730662:-","LOC101120991",0.947532513,-64,"chr2:80172918-80212927:+","LOC101120991","gi|560993608|ref|XP_006218920.1|",519,{"v":8e-101,"d":"8.00E-101"},"PREDICTED: lys-63-specific deubiquitinase BRCC36 isoform X2 [Vicugna pacos]","gi|466087081|ref|XM_004285932.1|",523,0,"PREDICTED: Orcinus orca BRCA1/BRCA2-containing complex, subunit 3 (BRCC3), transcript variant X2, mRNA","P46737",150,{"v":8e-100,"d":"8.00E-100"},"Lys-63-specific deubiquitinase BRCC36",".",".",".",".","pfam01398","JAB","JAB1/Mov34/MPN/PAD-1 ubiquitin protease. Members of this family are found in proteasome regulatory subunits, eukaryotic initiation factor 3 (eIF3) subunits and regulators of transcription factors. This family is also known as the MPN domain and PAD-1-like domain, JABP1 domain or JAMM domain. These are metalloenzymes that function as the ubiquitin isopeptidase/ deubiquitinase in the ubiquitin-based signaling and protein turnover pathways in eukaryotes. Versions of the domain in prokaryotic cognates of the ubiquitin-modification pathway are predicted to have a similar role.","GO:0006302|double-strand break repair;GO:0031572|G2 DNA damage checkpoint;GO:0070537|histone H2A K63-linked deubiquitination;GO:0045739|positive regulation of DNA repair;GO:0070536|protein K63-linked deubiquitination;GO:0010212|response to ionizing radiation;GO:0010165|response to X-ray;","GO:0070531|BRCA1-A complex;GO:0070552|BRISC complex;GO:0000152|nuclear ubiquitin ligase complex;GO:0005654|nucleoplasm;GO:0005634|nucleus;GO:0000151|ubiquitin ligase complex;","GO:0030234|enzyme regulator activity;GO:0046872|metal ion binding;GO:0008237|metallopeptidase activity;GO:0031593|polyubiquitin binding;GO:0004843|ubiquitin-specific protease activity;","K11864","BRCC3; BRCA1/BRCA2-containing complex subunit 3"]
["MYH15.1","chr1:171573069-171730662:-","LOC101120769",0.925538199,-64,"chr13:36172786-36193257:-","LOC101120769","gi|803134155|ref|XP_012043885.1|",4180,0,"PREDICTED: ankyrin repeat domain-containing protein 26-like isoform X1 [Ovis aries]","gi|556736353|ref|XM_005963714.1|",2295,0,"PREDICTED: Pantholops hodgsonii ankyrin repeat domain-containing protein 26-like (LOC102338170), mRNA","Q9UPS8",200,{"v":4e-51,"d":"4.00E-51"},"Ankyrin repeat domain-containing protein 26",".",".",".",".","pfam14915","CCDC144C","CCDC144C protein coiled-coil region. This family includes the human protein CCDC144C and the ankyrin repeat domain-containing protein 26-like 1 found in eukaryotes. Its function remains unknown, however, it is known to contain a coiled-coil domain which corresponds to this region. The ankyrin repeat which features in this protein is a common amino acid motif.","GO:0042593|glucose homeostasis;GO:0070373|negative regulation of ERK1 and ERK2 cascade;GO:0045599|negative regulation of fat cell differentiation;GO:0046627|negative regulation of insulin receptor signaling pathway;GO:0040015|negative regulation of multicellular organism growth;GO:0046621|negative regulation of organ growth;GO:0019217|regulation of fatty acid metabolic process;GO:0060259|regulation of feeding behavior;","GO:0005884|actin filament;GO:0005813|centrosome;",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","LOC101118712",0.909371255,-64,"chr11:41276667-41283493:-","LOC101118712","gi|803298816|ref|XP_012007908.1|",1695,0,"PREDICTED: keratin, type I cytoskeletal 42 isoform X3 [Ovis aries musimon]","gi|594063640|ref|XM_006055787.1|",926,0,"PREDICTED: Bubalus bubalis keratin, type I cytoskeletal 42-like (LOC102397719), mRNA","Q6IFX2",620,0,"Keratin, type I cytoskeletal 42",".",".",".",".","pfam00038","Filament","Intermediate filament protein.",".","GO:0005737|cytoplasm;GO:0005882|intermediate filament;","GO:0005198|structural molecule activity;","K07604","KRT1; type I keratin, acidic"]
["NR0B1","chrx:27539342-27553262:-","LOC101118534",0.905177685,-64,"chr8:54155350-54157351:+","LOC101118534","gi|440907352|gb|ELR57507.1|",2112,0,"Stress-induced-phosphoprotein 1, partial [Bos mutus]","gi|556744145|ref|XR_318930.1|",1705,0,"PREDICTED: Pantholops hodgsonii stress-induced-phosphoprotein 1 pseudogene (LOC102320520), misc_RNA","Q3ZBZ8",803,0,"Stress-induced-phosphoprotein 1",".",".",".",".","pfam13414","TPR_11","TPR repeat.",".","GO:0005737|cytoplasm;GO:0043209|myelin sheath;GO:0005634|nucleus;","GO:0044822|poly(A) RNA binding;","K09553","STIP1; stress-induced-phosphoprotein 1"]
["MYH15.1","chr1:171573069-171730662:-","LOC101117725",0.930734737,-64,"chr1:222228096-222229278:+","LOC101117725","gi|543354415|ref|XP_005521728.1|",547,{"v":5e-64,"d":"5.00E-64"},"PREDICTED: mortality factor 4-like protein 1 isoform X2 [Pseudopodoces humilis]","gi|593707204|ref|XM_007100187.1|",503,0,"PREDICTED: Physeter catodon mortality factor 4 like 1 (MORF4L1), transcript variant X2, mRNA","Q6AYU1",212,{"v":2e-64,"d":"2.00E-64"},"Mortality factor 4-like protein 1",".",".",".",".","pfam05712","MRG","MRG. This family consists of three different eukaryotic proteins (mortality factor 4 (MORF4/MRG15), male-specific lethal 3(MSL-3) and ESA1-associated factor 3(EAF3)). It is thought that the MRG family is involved in transcriptional regulation via histone acetylation. It contains 2 chromo domains and a leucine zipper motif.","GO:0008283|cell proliferation;GO:0006338|chromatin remodeling;GO:0006342|chromatin silencing;GO:0000724|double-strand break repair via homologous recombination;GO:0016575|histone deacetylation;GO:0043968|histone H2A acetylation;GO:0043967|histone H4 acetylation;GO:0040008|regulation of growth;GO:0006351|transcription, DNA-templated;","GO:0035267|NuA4 histone acetyltransferase complex;GO:0016580|Sin3 complex;","GO:0003682|chromatin binding;","K11339","MORF4L1, MRG15, EAF3; mortality factor 4-like protein 1"]
["MYH15.1","chr1:171573069-171730662:-","LOC101116757",0.916743955,-64,"chr14:41782212-41783467:-","LOC101116757","gi|348041212|ref|NP_001231703.1|",547,{"v":2e-169,"d":"2.00E-169"},"UDP-glucuronate decarboxylase 1 isoform b [Sus scrofa]","gi|329663220|ref|NM_001206064.1|",902,0,"Bos taurus UDP-glucuronate decarboxylase 1 (UXS1), mRNA","Q5R885",46.6,{"v":3e-168,"d":"3.00E-168"},"UDP-glucuronic acid decarboxylase 1","alr0657",160,{"v":1e-83,"d":"1.00E-83"},"COG0451","pfam11803","UXS1_N","UDP-glucuronate decarboxylase N-terminal. The N-terminus of the UDP-glucuronate decarboxylases may be involved in localisation to the perinuclear Golgi membrane.","GO:0051262|protein tetramerization;GO:0033320|UDP-D-xylose biosynthetic process;","GO:0070062|extracellular exosome;GO:0032580|Golgi cisterna membrane;GO:0016021|integral component of membrane;GO:0005739|mitochondrion;","GO:0070403|NAD+ binding;GO:0048040|UDP-glucuronate decarboxylase activity;","K08678","UXS1, uxs; UDP-glucuronate decarboxylase [EC:4.1.1.35]"]
["MYH15.1","chr1:171573069-171730662:-","LOC101116248",0.928794666,-64,"chr13:61936620-61982796:+","LOC101116248","gi|803139846|ref|XP_012044840.1|",2155,0,"PREDICTED: uncharacterized protein LOC101116248 isoform X1 [Ovis aries]","gi|548491806|ref|XM_005688659.1|",623,0,"PREDICTED: Capra hircus short palate, lung and nasal epithelium carcinoma-associated protein 2B-like (LOC102171351), mRNA","P79125",96.7,{"v":7e-21,"d":"7.00E-21"},"Short palate, lung and nasal epithelium carcinoma-associated protein 2B",".",".",".",".","pfam01273","LBP_BPI_CETP","LBP / BPI / CETP family, N-terminal domain. The N and C terminal domains of the LBP/BPI/CETP family are structurally similar.",".","GO:0005576|extracellular region;","GO:0008289|lipid binding;",".","."]
["MYH15.1","chr1:171573069-171730662:-","LOC101115564",0.925583652,-64,"chr14:51871309-51879465:-","LOC101115564","gi|426243934|ref|XP_004015795.1|",605,{"v":8e-73,"d":"8.00E-73"},"PREDICTED: uncharacterized protein LOC101115564 [Ovis aries]","gi|556732149|ref|XM_005961686.1|",391,0,"PREDICTED: Pantholops hodgsonii uncharacterized LOC102318508 (LOC102318508), mRNA",".",".",".",".",".",".",".",".","pfam05093","CIAPIN1","Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis. Anamorsin, subsequently named CIAPIN1 for cytokine-induced anti-apoptosis inhibitor 1, in humans is the homologue of yeast Dre2, a conserved soluble eukaryotic Fe-S cluster protein, that functions in cytosolic Fe-S protein biogenesis. It is found in both the cytoplasm and in the mitochondrial intermembrane space (IMS). CIAPIN1 is found to be up-regulated in hepatocellular cancer, is considered to be a downstream effector of the receptor tyrosine kinase-Ras signalling pathway, and is essential in mouse definitive haematopoiesis. Dre2 has been found to interact with the yeast reductase Tah18, forming a tight cytosolic complex implicated in the response to high levels of oxidative stress.",".",".",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","LOC101114215",0.954538101,-64,"chr17:71107188-71151374:-","LOC101114215","gi|803309418|ref|XP_012013095.1|",2815,0,"PREDICTED: sodium/glucose cotransporter 1-like isoform X2 [Ovis aries musimon]","gi|556733877|ref|XM_005962518.1|",1452,0,"PREDICTED: Pantholops hodgsonii sodium/glucose cotransporter 1-like (LOC102325212), mRNA","P53790",297,{"v":7e-89,"d":"7.00E-89"},"Sodium/glucose cotransporter 1","BH2222",109,{"v":5e-24,"d":"5.00E-24"},"COG4146","pfam00474","SSF","Sodium:solute symporter family. Membership of this family is supported by a significant blast score.","GO:0015758|glucose transport;GO:0050892|intestinal absorption;GO:0001656|metanephros development;","GO:0016324|apical plasma membrane;GO:0005903|brush border;GO:0070062|extracellular exosome;GO:0016021|integral component of membrane;","GO:0005355|glucose transmembrane transporter activity;GO:0005412|glucose:sodium symporter activity;","K14158","SLC5A1, SGLT1; solute carrier family 5 (sodium/glucose cotransporter), member 1"]
["MYH15.1","chr1:171573069-171730662:-","LOC101114176",0.913714645,-64,"chr2:160678931-160691293:-","LOC101114176","gi|594620650|ref|XP_007165030.1|",1088,{"v":8e-144,"d":"8.00E-144"},"PREDICTED: NADH dehydrogenase (ubiquinone) complex I, assembly factor 6, partial [Balaenoptera acutorostrata scammoni]","gi|556720403|ref|XR_318388.1|",942,0,"PREDICTED: Pantholops hodgsonii NADH dehydrogenase (ubiquinone) complex I, assembly factor 6-like (LOC102343561), misc_RNA","A7YVD7",418,{"v":1e-142,"d":"1.00E-142"},"NADH dehydrogenase (ubiquinone) complex I, assembly factor 6","AGc2873",66.2,{"v":2e-11,"d":"2.00E-11"},"COG1562","pfam00494","SQS_PSY","Squalene/phytoene synthase.","GO:0009058|biosynthetic process;GO:0032981|mitochondrial respiratory chain complex I assembly;","GO:0005743|mitochondrial inner membrane;","GO:0016740|transferase activity;","K18163","NDUFAF6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 6"]
["MYH15.1","chr1:171573069-171730662:-","LOC101113120",0.932204225,-64,"chr1:21221168-21226817:-","LOC101113120","gi|548460543|ref|XP_005678553.1|",499,{"v":2e-54,"d":"2.00E-54"},"PREDICTED: cytochrome P450 4A25-like, partial [Capra hircus]","gi|556731549|ref|XR_318653.1|",277,{"v":3e-141,"d":"3.00E-141"},"PREDICTED: Pantholops hodgsonii cytochrome P450 4A11-like (LOC102322956), misc_RNA","P14581",167,{"v":1e-44,"d":"1.00E-44"},"Cytochrome P450 4A7",".",".",".",".","pfam00067","p450","Cytochrome P450. Cytochrome P450s are haem-thiolate proteins involved in the oxidative degradation of various compounds. They are particularly well known for their role in the degradation of environmental toxins and mutagens. They can be divided into 4 classes, according to the method by which electrons from NAD(P)H are delivered to the catalytic site. Sequence conservation is relatively low within the family - there are only 3 absolutely conserved residues - but their general topography and structural fold are highly conserved. The conserved core is composed of a coil termed the 'meander', a four-helix bundle, helices J and K, and two sets of beta-sheets. These constitute the haem-binding loop (with an absolutely conserved cysteine that serves as the 5th ligand for the haem iron), the proton-transfer groove and the absolutely conserved EXXR motif in helix K. While prokaryotic P450s are soluble proteins, most eukaryotic P450s are associated with microsomal membranes. their general enzymatic function is to catalyse regiospecific and stereospecific oxidation of non-activated hydrocarbons at physiological temperatures.",".","GO:0005789|endoplasmic reticulum membrane;GO:0016021|integral component of membrane;","GO:0018685|alkane 1-monooxygenase activity;GO:0052869|arachidonic acid omega-hydroxylase activity;GO:0020037|heme binding;GO:0005506|iron ion binding;","K17687","CYP4A11; alkane 1-monooxygenase [EC:1.14.15.3]"]
["MYH15.1","chr1:171573069-171730662:-","LOC101113010",0.900150403,-64,"chr15:46261232-46262176:+","LOC101113010","gi|803163165|ref|XP_011951954.1|",1182,{"v":7e-160,"d":"7.00E-160"},"PREDICTED: olfactory receptor 56A1 [Ovis aries]","gi|548495450|ref|XM_005689792.1|",844,0,"PREDICTED: Capra hircus olfactory receptor 56A1-like (LOC102189055), mRNA","Q8NGH5",384,{"v":2e-131,"d":"2.00E-131"},"Olfactory receptor 56A1",".",".",".",".","pfam00001","7tm_1","7 transmembrane receptor (rhodopsin family). This family contains, amongst other G-protein-coupled receptors (GCPRs), members of the opsin family, which have been considered to be typical members of the rhodopsin superfamily. They share several motifs, mainly the seven transmembrane helices, GCPRs of the rhodopsin superfamily. All opsins bind a chromophore, such as 11-cis-retinal. The function of most opsins other than the photoisomerases is split into two steps: light absorption and G-protein activation. Photoisomerases, on the other hand, are not coupled to G-proteins - they are thought to generate and supply the chromophore that is used by visual opsins.","GO:0071880|adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0007267|cell-cell signaling;","GO:0005887|integral component of plasma membrane;GO:0005886|plasma membrane;","GO:0004930|G-protein coupled receptor activity;GO:0004984|olfactory receptor activity;","K04257","OLFR; olfactory receptor"]
["MYH15.1","chr1:171573069-171730662:-","LOC101111658",0.968642745,-64,"chr15:79512881-79513816:+","LOC101111658","gi|426246199|ref|XP_004016882.1|",1545,0,"PREDICTED: olfactory receptor 4D9-like [Ovis aries]","gi|594089449|ref|XM_006068084.1|",753,0,"PREDICTED: Bubalus bubalis olfactory receptor 4D9-like (LOC102396009), mRNA","Q8NGE8",490,{"v":2e-173,"d":"2.00E-173"},"Olfactory receptor 4D9",".",".",".",".","pfam13853","7tm_4","Olfactory receptor. The members of this family are transmembrane olfactory receptors.","GO:0050907|detection of chemical stimulus involved in sensory perception;GO:0007186|G-protein coupled receptor signaling pathway;","GO:0016021|integral component of membrane;GO:0005886|plasma membrane;","GO:0004930|G-protein coupled receptor activity;GO:0004984|olfactory receptor activity;GO:0004888|transmembrane signaling receptor activity;","K04257","OLFR; olfactory receptor"]
["MYH15.1","chr1:171573069-171730662:-","LOC101111417",0.919666971,-64,"chr1:263579446-263581507:-","LOC101111417","gi|441624216|ref|XP_004092981.1|",606,{"v":2e-96,"d":"2.00E-96"},"PREDICTED: LOW QUALITY PROTEIN: adiponectin receptor protein 1 [Nomascus leucogenys]","gi|594669492|ref|XM_007182679.1|",1077,0,"PREDICTED: Balaenoptera acutorostrata scammoni adiponectin receptor 1 (ADIPOR1), mRNA","Q96A54",74.7,{"v":5e-95,"d":"5.00E-95"},"Adiponectin receptor protein 1","SPBC12C2.09c",72,{"v":5e-18,"d":"5.00E-18"},"COG1272","pfam03006","HlyIII","Haemolysin-III related. Members of this family are integral membrane proteins. This family includes a protein with hemolytic activity from Bacillus cereus. It has been proposed that YOL002c encodes a Saccharomyces cerevisiae protein that plays a key role in metabolic pathways that regulate lipid and phosphate metabolizm. In eukaryotes, members are seven-transmembrane pass molecules found to encode functional receptors with a broad range of apparent ligand specificities, including progestin and adipoQ receptors, and hence have been named PAQR proteins. The mammalian members include progesterone binding proteins. Unlike the case with GPCR receptor proteins, the evolutionary ancestry of the members of this family can be traced back to the Archaea.","GO:0033211|adiponectin-activated signaling pathway;GO:0019395|fatty acid oxidation;GO:0007186|G-protein coupled receptor signaling pathway;GO:0042593|glucose homeostasis;GO:0009755|hormone-mediated signaling pathway;GO:0033210|leptin-mediated signaling pathway;GO:0030308|negative regulation of cell growth;GO:0046628|positive regulation of insulin receptor signaling pathway;GO:0046427|positive regulation of JAK-STAT cascade;GO:0010906|regulation of glucose metabolic process;GO:0019216|regulation of lipid metabolic process;","GO:0016021|integral component of membrane;GO:0031226|intrinsic component of plasma membrane;GO:0016020|membrane;GO:0005886|plasma membrane;","GO:0097003|adipokinetic hormone receptor activity;GO:0055100|adiponectin binding;GO:0046872|metal ion binding;GO:0019901|protein kinase binding;GO:0004872|receptor activity;","K07297","ADIPOR; adiponectin receptor"]
["MYH15.1","chr1:171573069-171730662:-","LOC101110500",0.94823127,-64,"chr4:104836217-104837189:+","LOC101110500","gi|426228137|ref|XP_004008171.1|",1646,0,"PREDICTED: olfactory receptor 9A4 [Ovis aries]","gi|555978362|ref|XM_005901064.1|",812,0,"PREDICTED: Bos mutus olfactory receptor 9A4-like (LOC102274211), mRNA","Q8NGU2",557,0,"Olfactory receptor 9A4",".",".",".",".","pfam13853","7tm_4","Olfactory receptor. The members of this family are transmembrane olfactory receptors.","GO:0007186|G-protein coupled receptor signaling pathway;","GO:0005887|integral component of plasma membrane;GO:0005886|plasma membrane;","GO:0004930|G-protein coupled receptor activity;GO:0004984|olfactory receptor activity;","K04257","OLFR; olfactory receptor"]
["MYH15.1","chr1:171573069-171730662:-","LOC101110483",0.927642143,-64,"chr2:54571896-54579893:-","LOC101110483","gi|803013707|ref|XP_011977380.1|",7004,0,"PREDICTED: putative spermatogenesis-associated protein 31D4 isoform X1 [Ovis aries]","gi|556719525|ref|XM_005955585.1|",3652,0,"PREDICTED: Pantholops hodgsonii SPATA31 subfamily D, member 1 (SPATA31D1), mRNA","Q6ZQQ2",342,{"v":4e-94,"d":"4.00E-94"},"Spermatogenesis-associated protein 31D1",".",".",".",".","pfam14650","FAM75","FAM75 family.","GO:0030154|cell differentiation;GO:0007283|spermatogenesis;","GO:0016021|integral component of membrane;",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","LOC101109309",0.903172897,-64,"chr21:39622291-39624149:+","LOC101109309","gi|426239353|ref|XP_004013586.1|",1190,{"v":9e-169,"d":"9.00E-169"},"PREDICTED: transmembrane protein 183A isoform X1 [Ovis aries]","gi|74354045|gb|BC102408.1|",1231,0,"Bos taurus transmembrane protein 183A, mRNA (cDNA clone MGC:127514 IMAGE:7949852), complete cds","Q5EA86",159,{"v":2e-169,"d":"2.00E-169"},"Transmembrane protein 183",".",".",".",".","pfam03348","Serinc","Serine incorporator (Serinc). This is a family of eukaryotic membrane proteins which incorporate serine into membranes and facilitate the synthesis of the serine-derived lipids phosphatidylserine and sphingolipid. Members of this family contain 11 transmembrane domains and form intracellular complexes with key enzymes involved in serine and sphingolipid biosynthesis.",".","GO:0016021|integral component of membrane;",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","LOC101107932",0.931720361,-64,"chrX:60923434-60927522:+","LOC101107932","gi|426257218|ref|XP_004022229.1|",1979,0,"PREDICTED: uncharacterized protein CXorf49 homolog [Ovis aries]","gi|556738989|ref|XM_005964999.1|",1654,0,"PREDICTED: Pantholops hodgsonii uncharacterized LOC102335835 (LOC102335835), mRNA",".",".",".",".",".",".",".",".","pfam15483","DUF4641","Domain of unknown function (DUF4641). This family of proteins is found in eukaryotes. Proteins in this family are typically between 201 and 519 amino acids in length.",".",".",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","LOC101107514",0.900338264,-64,"chr3:60334035-60335289:-","LOC101107514","gi|594030637|ref|XP_006040217.1|",641,{"v":2e-113,"d":"2.00E-113"},"PREDICTED: tubulin alpha-1A chain-like [Bubalus bubalis]","gi|548465455|ref|XM_005680002.1|",888,0,"PREDICTED: Capra hircus tubulin, alpha 1b (TUBA1B), mRNA","P34690",233,{"v":6e-97,"d":"6.00E-97"},"Tubulin alpha-2 chain","YML085c",207,{"v":1e-85,"d":"1.00E-85"},"COG5023","pfam03953","Tubulin_C","Tubulin C-terminal domain. This family includes the tubulin alpha, beta and gamma chains. Members of this family are involved in polymer formation. Tubulins are GTPases. FtsZ can polymerize into tubes, sheets, and rings in vitro and is ubiquitous in eubacteria and archaea. Tubulin is the major component of microtubules. (The FtsZ GTPases have been split into their won family).","GO:0051642|centrosome localization;GO:0009792|embryo development ending in birth or egg hatching;GO:0000132|establishment of mitotic spindle orientation;GO:0008104|protein localization;GO:0051258|protein polymerization;GO:0032465|regulation of cytokinesis;","GO:0005737|cytoplasm;GO:0005874|microtubule;","GO:0005525|GTP binding;GO:0003924|GTPase activity;GO:0005200|structural constituent of cytoskeleton;",".","."]
["MYH15.1","chr1:171573069-171730662:-","LOC101103117",0.923560385,-64,"chr24:36907472-36944152:-","LOC101103117","gi|724886829|ref|XP_010374064.1|",995,0,"PREDICTED: myosin-7-like [Rhinopithecus roxellana]","gi|466004718|ref|XM_004268916.1|",568,0,"PREDICTED: Orcinus orca myosin-7-like (LOC101289395), mRNA","Q91Z83",54.3,{"v":7e-130,"d":"7.00E-130"},"Myosin-7","SPCC645.05c",142,{"v":8e-45,"d":"8.00E-45"},"COG5022","pfam00063","Myosin_head","Myosin head (motor domain).","GO:0007512|adult heart development;GO:0046034|ATP metabolic process;GO:0060048|cardiac muscle contraction;GO:0006936|muscle contraction;GO:0030049|muscle filament sliding;GO:0002027|regulation of heart rate;GO:0031449|regulation of slow-twitch skeletal muscle fiber contraction;GO:0002026|regulation of the force of heart contraction;GO:0014728|regulation of the force of skeletal muscle contraction;GO:0000302|response to reactive oxygen species;GO:0003009|skeletal muscle contraction;GO:0006941|striated muscle contraction;GO:0014883|transition between fast and slow fiber;GO:0055010|ventricular cardiac muscle tissue morphogenesis;","GO:0005737|cytoplasm;GO:0005925|focal adhesion;GO:0005859|muscle myosin complex;GO:0030016|myofibril;GO:0016459|myosin complex;GO:0032982|myosin filament;GO:0005654|nucleoplasm;GO:0001725|stress fiber;GO:0030018|Z disc;","GO:0030898|actin-dependent ATPase activity;GO:0005524|ATP binding;GO:0016887|ATPase activity;GO:0000146|microfilament motor activity;","K17751","MYH6_7; myosin heavy chain 6/7"]
["MYH15.1","chr1:171573069-171730662:-","LOC101102987",0.911011179,-64,"chr8:57693776-57694810:-","LOC101102987","gi|426234799|ref|XP_004011379.1|",1740,0,"PREDICTED: trace amine-associated receptor 6 isoform X1 [Ovis aries]","gi|556744188|ref|XM_005967531.1|",954,0,"PREDICTED: Pantholops hodgsonii trace amine-associated receptor 6-like (LOC102327872), mRNA","Q5QD13",593,0,"Trace amine-associated receptor 6",".",".",".",".","pfam00001","7tm_1","7 transmembrane receptor (rhodopsin family). This family contains, amongst other G-protein-coupled receptors (GCPRs), members of the opsin family, which have been considered to be typical members of the rhodopsin superfamily. They share several motifs, mainly the seven transmembrane helices, GCPRs of the rhodopsin superfamily. All opsins bind a chromophore, such as 11-cis-retinal. The function of most opsins other than the photoisomerases is split into two steps: light absorption and G-protein activation. Photoisomerases, on the other hand, are not coupled to G-proteins - they are thought to generate and supply the chromophore that is used by visual opsins.","GO:0010579|positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway;GO:0007606|sensory perception of chemical stimulus;","GO:0005887|integral component of plasma membrane;","GO:0001594|trace-amine receptor activity;","K05051","TAAR; trace amine associated receptor"]
["MYH15.1","chr1:171573069-171730662:-","LOC101102818",0.950408087,-64,"chr8:20179821-20205266:-","LOC101102818","gi|426234469|ref|XP_004011218.1|",2119,0,"PREDICTED: leucine-rich repeat transmembrane protein FLRT1-like [Ovis aries]","gi|548479467|ref|XM_005684526.1|",2481,0,"PREDICTED: Capra hircus platelet glycoprotein V-like (LOC102170698), mRNA","O43155",102,{"v":2e-20,"d":"2.00E-20"},"Leucine-rich repeat transmembrane protein FLRT2","lin0372",52.8,9e-06,"COG4886","pfam13855","LRR_8","Leucine rich repeat.","GO:0007411|axon guidance;GO:0007155|cell adhesion;GO:0035556|intracellular signal transduction;GO:0051965|positive regulation of synapse assembly;GO:2001222|regulation of neuron migration;","GO:0070062|extracellular exosome;GO:0005615|extracellular space;GO:0005925|focal adhesion;GO:0005887|integral component of plasma membrane;GO:0005622|intracellular;GO:0005578|proteinaceous extracellular matrix;","GO:0045499|chemorepellent activity;GO:0030674|protein binding, bridging;GO:0005057|receptor signaling protein activity;","K16362","FLRT; leucine-rich repeat transmembrane protein FLRT"]
["MYH15.1","chr1:171573069-171730662:-","LOC101102610",0.919395324,-64,"chr1:17021991-17047088:+","LOC101102610","gi|803274317|ref|XP_011996829.1|",1503,0,"PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC101102610 isoform X5 [Ovis aries musimon]","gi|594620233|ref|XM_007164773.1|",1032,0,"PREDICTED: Balaenoptera acutorostrata scammoni uncharacterized LOC103012412 (LOC103012412), mRNA","O00370",100,{"v":2e-27,"d":"2.00E-27"},"LINE-1 retrotransposable element ORF2 protein",".",".",".",".","pfam01066","CDP-OH_P_transf","CDP-alcohol phosphatidyltransferase. All of these members have the ability to catalyse the displacement of CMP from a CDP-alcohol by a second alcohol with formation of a phosphodiester bond and concomitant breaking of a phosphoride anhydride bond.","GO:0006310|DNA recombination;GO:0090305|nucleic acid phosphodiester bond hydrolysis;GO:0032199|reverse transcription involved in RNA-mediated transposition;GO:0032197|transposition, RNA-mediated;",".","GO:0046872|metal ion binding;GO:0003964|RNA-directed DNA polymerase activity;GO:0009036|Type II site-specific deoxyribonuclease activity;",".","."]
["MYH15.1","chr1:171573069-171730662:-","LINGO3",0.983212455,-64,"chr5:18769687-18773977:+","LINGO3","gi|803300112|ref|XP_012008566.1|",1508,0,"PREDICTED: leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3 isoform X2 [Ovis aries musimon]","gi|594046906|ref|XM_006047823.1|",1801,0,"PREDICTED: Bubalus bubalis leucine rich repeat and Ig domain containing 3 (LINGO3), mRNA","P0C6S8",531,{"v":7e-171,"d":"7.00E-171"},"Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3",".",".",".",".","pfam13855","LRR_8","Leucine rich repeat.",".","GO:0016021|integral component of membrane;",".",".","."]
["NYAP1","chr24:35900853-35960797:-","LENG9",0.91281051,-64,"chr14:60036781-60039475:-","LENG9","gi|803153281|ref|XP_011950594.1|",1685,0,"PREDICTED: leukocyte receptor cluster member 9 isoform X1 [Ovis aries]","gi|594080956|ref|XM_006064045.1|",1068,0,"PREDICTED: Bubalus bubalis leukocyte receptor cluster (LRC) member 9 (LENG9), mRNA","Q8BTN6",239,{"v":2e-68,"d":"2.00E-68"},"Leukocyte receptor cluster member 9",".",".",".",".","pfam10469","AKAP7_NLS","AKAP7 2'5' RNA ligase-like domain. AKAP7_NLS is the N-terminal domain of the cyclic AMP-dependent protein kinase A, PKA, anchor protein AKAP7. This protein anchors PKA for its role in regulating PKA-mediated gene transcription in both somatic cells and oocytes. AKAP7_NLS carries the nuclear localisation signal (NLS) KKRKK, that indicates the cellular destiny of this anchor protein. Binding to the regulatory subunits RI and RII of PKA is mediated via the family AKAP7_RIRII_bdg. at the C-terminus. This family represents a region that contains two 2'5' RNA ligase like domains pfam02834. Presumably this domain carried out some as yet unknown enzymatic function.","GO:0098779|mitophagy in response to mitochondrial depolarization;GO:0002230|positive regulation of defense response to virus by host;",".","GO:0046872|metal ion binding;",".","."]
["MYH15.1","chr1:171573069-171730662:-","KREMEN2",0.936721647,-64,"chr24:2354851-2358775:+","KREMEN2","gi|803197621|ref|XP_011960135.1|",1725,0,"PREDICTED: kremen protein 2 isoform X1 [Ovis aries]","gi|157743214|gb|BC149793.1|",961,0,"Bos taurus cDNA clone IMAGE:8465796","Q8NCW0",67,{"v":2e-10,"d":"2.00E-10"},"Kremen protein 2",".",".",".",".","pfam01822","WSC","WSC domain. This domain may be involved in carbohydrate binding.","GO:0007154|cell communication;GO:0090090|negative regulation of canonical Wnt signaling pathway;GO:0016055|Wnt signaling pathway;","GO:0031901|early endosome membrane;GO:0016021|integral component of membrane;GO:0016020|membrane;GO:0005886|plasma membrane;",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","IQCF2",0.918730204,-64,"chr19:48994982-49002750:-","IQCF2","gi|803234449|ref|XP_011977346.1|",988,{"v":1e-128,"d":"1.00E-128"},"PREDICTED: IQ domain-containing protein F2 isoform X3 [Ovis aries musimon]","gi|548515469|ref|XM_005695901.1|",550,0,"PREDICTED: Capra hircus IQ motif containing F2 (IQCF2), transcript variant X1, mRNA",".",".",".",".",".",".",".",".","pfam14214","Helitron_like_N","Helitron helicase-like domain at N-terminus. This family is found in Helitrons, recently recognized eukaryotic transposons that are predicted to amplify by a rolling-circle mechanism. In many instances a protein-coding gene is disrupted by their insertion.",".",".",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","IGSF9B",0.917385216,-64,"chr21:32277060-32312561:+","IGSF9B","gi|803190775|ref|XP_011957290.1|",6081,0,"PREDICTED: LOW QUALITY PROTEIN: protein turtle homolog B isoform X1 [Ovis aries]","gi|602730089|ref|XM_007450398.1|",2975,0,"PREDICTED: Lipotes vexillifer immunoglobulin superfamily, member 9B (IGSF9B), mRNA","Q9UPX0",2139,0,"Protein turtle homolog B",".",".",".",".","pfam07679","I-set","Immunoglobulin I-set domain.","GO:0007156|homophilic cell adhesion via plasma membrane adhesion molecules;GO:0097151|positive regulation of inhibitory postsynaptic potential;","GO:0030425|dendrite;GO:0060077|inhibitory synapse;GO:0016021|integral component of membrane;GO:0043025|neuronal cell body;GO:0005886|plasma membrane;",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","HRH3",0.938820282,-64,"chr13:54212968-54231055:+","HRH3","gi|803139533|ref|XP_012044821.1|",1857,0,"PREDICTED: histamine H3 receptor isoform X1 [Ovis aries]","gi|556751382|ref|XM_005971033.1|",1100,0,"PREDICTED: Pantholops hodgsonii histamine receptor H3 (HRH3), mRNA","Q9JI35",624,0,"Histamine H3 receptor",".",".",".",".","pfam00001","7tm_1","7 transmembrane receptor (rhodopsin family). This family contains, amongst other G-protein-coupled receptors (GCPRs), members of the opsin family, which have been considered to be typical members of the rhodopsin superfamily. They share several motifs, mainly the seven transmembrane helices, GCPRs of the rhodopsin superfamily. All opsins bind a chromophore, such as 11-cis-retinal. The function of most opsins other than the photoisomerases is split into two steps: light absorption and G-protein activation. Photoisomerases, on the other hand, are not coupled to G-proteins - they are thought to generate and supply the chromophore that is used by visual opsins.","GO:0001505|regulation of neurotransmitter levels;","GO:0016021|integral component of membrane;GO:0005886|plasma membrane;","GO:0004969|histamine receptor activity;",".","."]
["MYH15.1","chr1:171573069-171730662:-","HCN3",0.901702649,-64,"chr1:103907639-103920644:+","HCN3","gi|803006609|ref|XP_011962697.1|",3109,0,"PREDICTED: LOW QUALITY PROTEIN: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 isoform X1 [Ovis aries]","gi|556759662|ref|XM_005975094.1|",1782,0,"PREDICTED: Pantholops hodgsonii hyperpolarization activated cyclic nucleotide-gated potassium channel 3 (HCN3), mRNA","Q9P1Z3",88.6,{"v":2e-16,"d":"2.00E-16"},"Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3","mll3241_2",62.4,{"v":5e-10,"d":"5.00E-10"},"COG0664","pfam08412","Ion_trans_N","Ion transport protein N-terminal. This metazoan domain is found to the N-terminus of pfam00520 in voltage- and cyclic nucleotide-gated K/Na ion channels.","GO:1903351|cellular response to dopamine;GO:0071805|potassium ion transmembrane transport;GO:0042391|regulation of membrane potential;GO:0072718|response to cisplatin;GO:0035725|sodium ion transmembrane transport;GO:0007268|synaptic transmission;","GO:0044316|cone cell pedicle;GO:0030425|dendrite;GO:0005887|integral component of plasma membrane;GO:0043025|neuronal cell body;GO:0005886|plasma membrane;GO:0045202|synapse;","GO:0030552|cAMP binding;GO:0005249|voltage-gated potassium channel activity;GO:0005248|voltage-gated sodium channel activity;","K04956","HCN3; hyperpolarization activated cyclic nucleotide-gated potassium channel 3"]
["MYH15.1","chr1:171573069-171730662:-","HAPLN2",0.901270567,-64,"chr1:105044647-105053350:+","HAPLN2","gi|803006621|ref|XP_011962737.1|",1431,0,"PREDICTED: hyaluronan and proteoglycan link protein 2 isoform X1, partial [Ovis aries]","gi|594055617|ref|XM_006051968.1|",1148,0,"PREDICTED: Bubalus bubalis hyaluronan and proteoglycan link protein 2 (HAPLN2), transcript variant X4, mRNA","Q9ESM3",57.8,5e-07,"Hyaluronan and proteoglycan link protein 2",".",".",".",".","pfam00193","Xlink","Extracellular link domain.","GO:0007155|cell adhesion;GO:0007417|central nervous system development;GO:0008065|establishment of blood-nerve barrier;GO:0085029|extracellular matrix assembly;GO:0001501|skeletal system development;","GO:0005578|proteinaceous extracellular matrix;","GO:0005540|hyaluronic acid binding;","K06851","HAPLN2; hyaluronan and proteoglycan link protein 2"]
["MYH15.1","chr1:171573069-171730662:-","GRIN3B",0.953990011,-64,"chr5:40835716-40844833:+","GRIN3B","gi|426230961|ref|XP_004009527.1|",4574,0,"PREDICTED: LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 3B isoform X1, partial [Ovis aries]","gi|594052463|ref|XM_006050483.1|",1730,0,"PREDICTED: Bubalus bubalis glutamate receptor, ionotropic, N-methyl-D-aspartate 3B (GRIN3B), mRNA","O60391",1311,0,"Glutamate receptor ionotropic, NMDA 3B",".",".",".",".","pfam00060","Lig_chan","Ligand-gated ion channel. This family includes the four transmembrane regions of the ionotropic glutamate receptors and NMDA receptors.","GO:0034220|ion transmembrane transport;GO:0035235|ionotropic glutamate receptor signaling pathway;GO:0051205|protein insertion into membrane;GO:0051924|regulation of calcium ion transport;GO:0035249|synaptic transmission, glutamatergic;","GO:0030054|cell junction;GO:0030425|dendrite;GO:0017146|NMDA selective glutamate receptor complex;GO:0043025|neuronal cell body;GO:0005886|plasma membrane;GO:0045211|postsynaptic membrane;","GO:0005262|calcium channel activity;GO:0005261|cation channel activity;GO:0005234|extracellular-glutamate-gated ion channel activity;GO:0016594|glycine binding;GO:0004972|NMDA glutamate receptor activity;GO:0042165|neurotransmitter binding;GO:0030594|neurotransmitter receptor activity;","K05214","GRIN3B; glutamate receptor ionotropic, NMDA 3B"]
["MYH15.1","chr1:171573069-171730662:-","GIMD1",0.948667663,-64,"chr6:18937347-18951586:+","GIMD1","gi|803081650|ref|XP_004009690.2|",1165,{"v":5e-145,"d":"5.00E-145"},"PREDICTED: GTPase IMAP family member GIMD1 [Ovis aries]","gi|593762704|ref|XM_007119937.1|",1326,0,"PREDICTED: Physeter catodon GIMAP family P-loop NTPase domain containing 1 (GIMD1), mRNA","G3MZQ6",434,{"v":2e-142,"d":"2.00E-142"},"GTPase IMAP family member GIMD1",".",".",".",".","pfam04548","AIG1","AIG1 family. Arabidopsis protein AIG1 appears to be involved in plant resistance to bacteria.",".",".","GO:0005525|GTP binding;",".","."]
["MYH15.1","chr1:171573069-171730662:-","GABRQ",0.903078646,-64,"chrX:78354300-78373253:-","GABRQ","gi|803203374|ref|XP_011962535.1|",3087,0,"PREDICTED: gamma-aminobutyric acid receptor subunit theta [Ovis aries]","gi|548530221|ref|XM_005700490.1|",1106,0,"PREDICTED: Capra hircus gamma-aminobutyric acid (GABA) A receptor, theta (GABRQ), mRNA","Q9UN88",732,0,"Gamma-aminobutyric acid receptor subunit theta",".",".",".",".","pfam02931","Neur_chan_LBD","Neurotransmitter-gated ion-channel ligand binding domain. This family is the extracellular ligand binding domain of these ion channels. This domain forms a pentameric arrangement in the known structure.","GO:1902476|chloride transmembrane transport;GO:0034220|ion transmembrane transport;GO:0050877|neurological system process;GO:0006836|neurotransmitter transport;GO:0042391|regulation of membrane potential;GO:0007165|signal transduction;GO:0007268|synaptic transmission;GO:0055085|transmembrane transport;","GO:0030054|cell junction;GO:0034707|chloride channel complex;GO:1902711|GABA-A receptor complex;GO:0005887|integral component of plasma membrane;GO:0043005|neuron projection;GO:0005886|plasma membrane;GO:0045211|postsynaptic membrane;GO:0043235|receptor complex;GO:0045202|synapse;","GO:0005254|chloride channel activity;GO:0005230|extracellular ligand-gated ion channel activity;GO:0004890|GABA-A receptor activity;GO:0005326|neurotransmitter transporter activity;GO:0004888|transmembrane signaling receptor activity;","K05192","GABRQ; gamma-aminobutyric acid receptor subunit theta"]
["MYH15.1","chr1:171573069-171730662:-","FSHB",0.952868699,-64,"chr15:59077783-59081578:+","FSHB","gi|57619324|ref|NP_001009798.1|",682,{"v":4e-84,"d":"4.00E-84"},"follitropin subunit beta precursor [Ovis aries]","gi|57619323|ref|NM_001009798.1|",1561,0,"Ovis aries follicle stimulating hormone, beta polypeptide (FSHB), mRNA","P01227",267,{"v":1e-85,"d":"1.00E-85"},"Follitropin subunit beta",".",".",".",".","pfam00007","Cys_knot","Cystine-knot domain. The family comprises glycoprotein hormones and the C-terminal domain of various extracellular proteins. It is believed to be involved in disulfide-linked dimerization.","GO:0035938|estradiol secretion;","GO:0005623|cell;GO:0005576|extracellular region;",".","K05250","FSH; follicle stimulating hormone"]
["MYH15.1","chr1:171573069-171730662:-","FSCN3",0.900864765,-64,"chr4:91879562-91887888:+","FSCN3","gi|803253891|ref|XP_011986907.1|",3221,0,"PREDICTED: fascin-3-like isoform X1 [Ovis aries musimon]","gi|548463848|ref|XM_005679430.1|",1727,0,"PREDICTED: Capra hircus fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus) (FSCN3), mRNA","Q9QXW4",734,0,"Fascin-3",".",".",".",".","pfam06268","Fascin","Fascin domain. This family consists of several eukaryotic fascin or singed proteins. The fascins are a structurally unique and evolutionarily conserved group of actin cross-linking proteins. Fascins function in the organisation of two major forms of actin-based structures: dynamic, cortical cell protrusions and cytoplasmic microfilament bundles. The cortical structures, which include filopodia, spikes, lamellipodial ribs, oocyte microvilli and the dendrites of dendritic cells, have roles in cell-matrix adhesion, cell interactions and cell migration, whereas the cytoplasmic actin bundles appear to participate in cell architecture.  Dictyostelium hisactophilin, another actin-binding protein, is a submembranous pH sensor that signals slight changes of the H+ concentration to actin by inducing actin polymerization and binding to microfilaments only at pH values below seven. Members of this family are histidine rich, typically contain the repeated motif of HHXH.","GO:0030036|actin cytoskeleton organization;GO:0007015|actin filament organization;GO:0007286|spermatid development;","GO:0015629|actin cytoskeleton;GO:0005737|cytoplasm;","GO:0003779|actin binding;GO:0051015|actin filament binding;","K17456","FSCN3; fascin 3"]
["MYH15.1","chr1:171573069-171730662:-","FCRL4",0.955556635,-64,"chr1:106391544-106426388:-","FCRL4","gi|802992185|ref|XP_012039201.1|",2879,0,"PREDICTED: Fc receptor-like protein 4 isoform X3 [Ovis aries]","gi|594052679|ref|XM_006050587.1|",1730,0,"PREDICTED: Bubalus bubalis Fc receptor-like 4 (FCRL4), mRNA","Q96PJ5",98.2,{"v":4e-20,"d":"4.00E-20"},"Fc receptor-like protein 4",".",".",".",".","pfam13895","Ig_2","Immunoglobulin domain. This domain contains immunoglobulin-like domains.","GO:0002376|immune system process;","GO:0070062|extracellular exosome;GO:0016021|integral component of membrane;GO:0005886|plasma membrane;",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","FAM196B",0.943148796,-64,"chr16:1814937-1938746:-","FAM196B","gi|426246249|ref|XP_004016907.1|",2521,0,"PREDICTED: protein FAM196B [Ovis aries]","gi|594105252|ref|XM_006075522.1|",2342,0,"PREDICTED: Bubalus bubalis family with sequence similarity 196, member B (FAM196B), transcript variant X2, mRNA",".",".",".",".",".",".",".",".","pfam15265","FAM196","FAM196 family. This protein family is a domain of unknown function. This family of proteins is found in eukaryotes and are typically between 441 and 534 amino acids in length.",".",".",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","FAM170A",0.965663132,-64,"chr5:31666156-31672615:-","FAM170A","gi|803073725|ref|XP_012033629.1|",1374,{"v":9e-177,"d":"9.00E-177"},"PREDICTED: protein FAM170A isoform X1 [Ovis aries]","gi|556729288|ref|XM_005960299.1|",1160,0,"PREDICTED: Pantholops hodgsonii family with sequence similarity 170, member A (FAM170A), mRNA","A1A519",390,{"v":8e-126,"d":"8.00E-126"},"Protein FAM170A",".",".",".",".","pfam15449","Retinal","Retinal protein. This family of proteins is found in the photoreceptor cells of the retina. Mutations of the gene encoding this protein have been associated with retinal disorders such as retinitis pigmentosa and late-onset progressive retinal atrophy. The function of this family of proteins is unknown, but it is likely to be important in the development and function of the retina.","GO:0045893|positive regulation of transcription, DNA-templated;GO:0006366|transcription from RNA polymerase II promoter;","GO:0005634|nucleus;","GO:0003677|DNA binding;GO:0046872|metal ion binding;",".","."]
["MYH15.1","chr1:171573069-171730662:-","EXOC3L2",0.961074416,-64,"chr14:51824489-51871479:-","EXOC3L2","gi|803247132|ref|XP_011983563.1|",2116,0,"PREDICTED: exocyst complex component 3-like protein 2 isoform X7 [Ovis aries musimon]","gi|594088253|ref|XM_006067519.1|",1229,0,"PREDICTED: Bubalus bubalis exocyst complex component 3-like 2 (EXOC3L2), mRNA","Q2M3D2",546,0,"Exocyst complex component 3-like protein 2",".",".",".",".","pfam06046","Sec6","Exocyst complex component Sec6. Sec6 is a component of the multiprotein exocyst complex. Sec6 interacts with Sec8, Sec10 and Exo70.These exocyst proteins localize to regions of active exocytosis-at the growing ends of interphase cells and in the medial region of cells undergoing cytokinesis-in an F-actin-dependent and exocytosis- independent manner.","GO:0051601|exocyst localization;GO:0006887|exocytosis;","GO:0000145|exocyst;","GO:0000149|SNARE binding;",".","."]
["MYH15.1","chr1:171573069-171730662:-","EPS8",0.916322853,-64,"chr3:198717803-198924833:+","EPS8","gi|594056467|ref|XP_006052438.1|",3982,0,"PREDICTED: epidermal growth factor receptor kinase substrate 8 isoform X1 [Bubalus bubalis]","gi|594056466|ref|XM_006052376.1|",3576,0,"PREDICTED: Bubalus bubalis epidermal growth factor receptor pathway substrate 8 (EPS8), transcript variant X1, mRNA","Q12929",1306,0,"Epidermal growth factor receptor kinase substrate 8",".",".",".",".","pfam08416","PTB","Phosphotyrosine-binding domain. The phosphotyrosine-binding domain (PTB, also phosphotyrosine-interaction or PI domain) in the protein tensin tends to be found at the C-terminus. Tensin is a multi-domain protein that binds to actin filaments and functions as a focal-adhesion molecule (focal adhesions are regions of plasma membrane through which cells attach to the extracellular matrix). Human tensin has actin-binding sites, an SH2 (pfam00017) domain and a region similar to the tumor suppressor PTEN. The PTB domain interacts with the cytoplasmic tails of beta integrin by binding to an NPXY motif.","GO:0051764|actin crosslink formation;GO:0031532|actin cytoskeleton reorganization;GO:0051017|actin filament bundle assembly;GO:0070358|actin polymerization-dependent cell motility;GO:0008344|adult locomotory behavior;GO:0051016|barbed-end actin filament capping;GO:0048149|behavioral response to ethanol;GO:0008283|cell proliferation;GO:0036336|dendritic cell migration;GO:0007173|epidermal growth factor receptor signaling pathway;GO:0010458|exit from mitosis;GO:0009967|positive regulation of signal transduction;GO:0016601|Rac protein signal transduction;GO:0030832|regulation of actin filament length;GO:0008360|regulation of cell shape;GO:0007165|signal transduction;","GO:0005903|brush border;GO:0005938|cell cortex;GO:0030054|cell junction;GO:0070062|extracellular exosome;GO:0030426|growth cone;GO:0017146|NMDA selective glutamate receptor complex;GO:0014069|postsynaptic density;GO:0032587|ruffle membrane;GO:0032420|stereocilium;GO:0031982|vesicle;","GO:0003779|actin binding;GO:0048365|Rac GTPase binding;GO:0005070|SH3/SH2 adaptor activity;","K17277","EPS8; epidermal growth factor receptor kinase substrate 8"]
["NYAP1","chr24:35900853-35960797:-","EFNB1",0.922664405,-64,"chrX:58286378-58297687:+","EFNB1","gi|122692477|ref|NP_001073768.1|",1566,0,"ephrin-B1 precursor [Bos taurus]","gi|555968413|ref|XM_005896180.1|",1398,0,"PREDICTED: Bos mutus ephrin-B1 (EFNB1), mRNA","P98172",594,0,"Ephrin-B1",".",".",".",".","pfam00812","Ephrin","Ephrin.","GO:0007411|axon guidance;GO:0007155|cell adhesion;GO:0007267|cell-cell signaling;GO:0009880|embryonic pattern specification;GO:0048013|ephrin receptor signaling pathway;GO:0001755|neural crest cell migration;GO:0042102|positive regulation of T cell proliferation;","GO:0005737|cytoplasm;GO:0070062|extracellular exosome;GO:0005887|integral component of plasma membrane;GO:0045121|membrane raft;GO:0005634|nucleus;GO:0005886|plasma membrane;GO:0045202|synapse;","GO:0046875|ephrin receptor binding;","K05463","EFNB; ephrin-B"]
["MYH15.1","chr1:171573069-171730662:-","DLX1",0.915120487,-64,"chr2:136608104-136611211:-","DLX1","gi|635058762|ref|XP_007963553.1|",981,{"v":8e-128,"d":"8.00E-128"},"PREDICTED: homeobox protein DLX-1 isoform X2 [Chlorocebus sabaeus]","gi|545555217|ref|XM_005640314.1|",1011,0,"PREDICTED: Canis lupus familiaris distal-less homeobox 1 (DLX1), transcript variant X7, mRNA","P56177",365,{"v":2e-123,"d":"2.00E-123"},"Homeobox protein DLX-1",".",".",".",".","pfam00046","Homeobox","Homeobox domain.","GO:0021893|cerebral cortex GABAergic interneuron fate commitment;GO:0048706|embryonic skeletal system development;GO:0021766|hippocampus development;GO:0043524|negative regulation of neuron apoptotic process;GO:0045746|negative regulation of Notch signaling pathway;GO:0048715|negative regulation of oligodendrocyte differentiation;GO:0000122|negative regulation of transcription from RNA polymerase II promoter;GO:0042475|odontogenesis of dentin-containing tooth;GO:0009954|proximal/distal pattern formation;GO:0021882|regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment;GO:0021544|subpallium development;","GO:0005634|nucleus;","GO:0003682|chromatin binding;GO:0000977|RNA polymerase II regulatory region sequence-specific DNA binding;","K09314","DLX1_4_6; homeobox protein DLX1/4/6"]
["MYH15.1","chr1:171573069-171730662:-","DESI2",0.913237311,-64,"chr12:30598688-30643719:-","DESI2","gi|594668996|ref|XP_007182510.1|",895,{"v":5e-108,"d":"5.00E-108"},"PREDICTED: desumoylating isopeptidase 2 isoform X1 [Balaenoptera acutorostrata scammoni]","gi|548498016|ref|XM_005690556.1|",3181,0,"PREDICTED: Capra hircus desumoylating isopeptidase 2 (DESI2), mRNA","Q5R456",312,{"v":3e-95,"d":"3.00E-95"},"Desumoylating isopeptidase 2",".",".",".",".","pfam05903","Peptidase_C97","PPPDE putative peptidase domain. The PPPDE superfamily (after Permuted Papain fold Peptidases of DsRNA viruses and Eukaryotes), consists of predicted thiol peptidases with a circularly permuted papain-like fold. The inference of the likely DUB function of the PPPDE superfamily proteins is based on the fusions of the catalytic domain to Ub-binding PUG (PUB)/UBA domains and a novel alpha-helical Ub-associated domain (the PUL domain, after PLAP, Ufd3p and Lub1p).",".","GO:0005737|cytoplasm;","GO:0008233|peptidase activity;",".","."]
["NYAP1","chr24:35900853-35960797:-","DDX49",0.935189601,-64,"chr5:4027012-4034929:-","DDX49","gi|803248168|ref|XP_011984054.1|",1451,0,"PREDICTED: probable ATP-dependent RNA helicase DDX49 isoform X2 [Ovis aries musimon]","gi|548471563|ref|XM_005682100.1|",1848,0,"PREDICTED: Capra hircus DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 (DDX49), mRNA","Q9Y6V7",543,0,"Probable ATP-dependent RNA helicase DDX49",".",".",".",".","pfam00270","DEAD","DEAD/DEAH box helicase. Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolizm, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.","GO:0010501|RNA secondary structure unwinding;",".","GO:0005524|ATP binding;GO:0004004|ATP-dependent RNA helicase activity;GO:0044822|poly(A) RNA binding;","K14778","DDX49, DBP8; ATP-dependent RNA helicase DDX49/DBP8 [EC:3.6.4.13]"]
["MYH15.1","chr1:171573069-171730662:-","DCST1",0.913156922,-64,"chr1:103712321-103728264:+","DCST1","gi|426216747|ref|XP_004002619.1|",1694,0,"PREDICTED: LOW QUALITY PROTEIN: DC-STAMP domain-containing protein 1 isoform X6 [Ovis aries]","gi|548457263|ref|XM_005677411.1|",1123,0,"PREDICTED: Capra hircus DC-STAMP domain containing 1 (DCST1), transcript variant X2, mRNA","Q5T197",516,0,"DC-STAMP domain-containing protein 1",".",".",".",".","pfam07782","DC_STAMP","DC-STAMP-like protein. This is a family of sequences which are similar to a region of the dendritic cell-specific transmembrane protein (DC-STAMP). This is thought to be a novel receptor protein that shares no identity with other multimembrane-spanning proteins. It is thought to have seven putative transmembrane regions, two of which are found in the region featured in this family. DC-STAMP is also described as having potential N-linked glycosylation sites and a potential phosphorylation site for PKC, but these are not conserved throughout the family.",".","GO:0016021|integral component of membrane;","GO:0008270|zinc ion binding;",".","."]
["MYH15.1","chr1:171573069-171730662:-","DBX1",0.917069659,-64,"chr21:24034511-24043046:+","DBX1","gi|426251581|ref|XP_004019500.1|",1347,{"v":2e-167,"d":"2.00E-167"},"PREDICTED: homeobox protein DBX1 [Ovis aries]","gi|149642748|ref|NM_001098998.1|",1631,0,"Bos taurus developing brain homeobox 1 (DBX1), mRNA","A5PKG8",510,{"v":7e-164,"d":"7.00E-164"},"Homeobox protein DBX1",".",".",".",".","pfam00046","Homeobox","Homeobox domain.","GO:0006357|regulation of transcription from RNA polymerase II promoter;GO:0021521|ventral spinal cord interneuron specification;","GO:0005634|nucleus;","GO:0043565|sequence-specific DNA binding;",".","."]
["MYH15.1","chr1:171573069-171730662:-","CSN1S2",0.924134549,-64,"chr6:85097149-85113820:+","CSN1S2","gi|284025656|gb|ADB65931.1|",987,{"v":3e-131,"d":"3.00E-131"},"alpha-s2-casein [Ovis aries]","gi|57164370|ref|NM_001009363.1|",1000,0,"Ovis aries alpha-S2-casein (CSN1S2), mRNA","P04654",383,{"v":4e-132,"d":"4.00E-132"},"Alpha-S2-casein",".",".",".",".","pfam00363","Casein","Casein.",".","GO:0005576|extracellular region;","GO:0005215|transporter activity;",".","."]
["MYH15.1","chr1:171573069-171730662:-","COL22A1",0.90896805,-64,"chr9:16903240-17128643:+","COL22A1","gi|803267556|ref|XP_011993524.1|",1572,0,"PREDICTED: collagen alpha-1(XXII) chain isoform X2 [Ovis aries musimon]","gi|556773900|ref|XM_005982034.1|",2841,0,"PREDICTED: Pantholops hodgsonii collagen, type XXII, alpha 1 (COL22A1), mRNA","Q8NFW1",108,{"v":4e-22,"d":"4.00E-22"},"Collagen alpha-1(XXII) chain",".",".",".",".","pfam01391","Collagen","Collagen triple helix repeat (20 copies). Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxyproline. Collagens are post translationally modified by proline hydroxylase to form the hydroxyproline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure.","GO:0030198|extracellular matrix organization;","GO:0005581|collagen trimer;GO:0005788|endoplasmic reticulum lumen;GO:0005576|extracellular region;GO:0005578|proteinaceous extracellular matrix;",".","K16630","COL22A; collagen, type XXII, alpha"]
["MYH15","chr1:171569543-171575119:+","CLIP2",0.931424675,-64,"chr24:32958213-33011871:-","CLIP2","gi|803236822|ref|XP_011978540.1|",2466,0,"PREDICTED: CAP-Gly domain-containing linker protein 2 isoform X2 [Ovis aries musimon]","gi|556753834|ref|XM_005972228.1|",3315,0,"PREDICTED: Pantholops hodgsonii CAP-GLY domain containing linker protein 2 (CLIP2), mRNA","Q9UDT6",60.1,2e-07,"CAP-Gly domain-containing linker protein 2","ECU06g0410",71.2,{"v":2e-12,"d":"2.00E-12"},"COG5244","pfam01302","CAP_GLY","CAP-Gly domain. Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.",".","GO:0005881|cytoplasmic microtubule;GO:0005875|microtubule associated complex;GO:0035371|microtubule plus-end;",".","K10422","CLIP2, CYLN2; CAP-Gly domain-containing linker protein 2"]
["MYH15.1","chr1:171573069-171730662:-","CHRNA4",0.94953194,-64,"chr13:53488296-53497940:+","CHRNA4","gi|803139421|ref|XP_012044814.1|",2163,0,"PREDICTED: neuronal acetylcholine receptor subunit alpha-4 isoform X1, partial [Ovis aries]","gi|300798277|ref|NM_001192900.1|",1174,0,"Bos taurus cholinergic receptor, nicotinic, alpha 4 (neuronal) (CHRNA4), mRNA","Q5IS77",727,0,"Neuronal acetylcholine receptor subunit alpha-4",".",".",".",".","pfam02931","Neur_chan_LBD","Neurotransmitter-gated ion-channel ligand binding domain. This family is the extracellular ligand binding domain of these ion channels. This domain forms a pentameric arrangement in the known structure.","GO:0035095|behavioral response to nicotine;GO:0098655|cation transmembrane transport;GO:0006812|cation transport;GO:0050890|cognition;GO:0006281|DNA repair;GO:0050877|neurological system process;GO:0001666|response to hypoxia;GO:0006979|response to oxidative stress;GO:0007165|signal transduction;GO:0007268|synaptic transmission;","GO:0005892|acetylcholine-gated channel complex;GO:0030054|cell junction;GO:0045211|postsynaptic membrane;","GO:0015464|acetylcholine receptor activity;GO:0004889|acetylcholine-activated cation-selective channel activity;","K04806","CHRNA4; nicotinic acetylcholine receptor alpha-4"]
["MYH15.1","chr1:171573069-171730662:-","C3H2orf78",0.910885911,-64,"chr3:95422182-95430429:+","C3H2orf78","gi|803040959|ref|XP_012029042.1|",4511,0,"PREDICTED: uncharacterized protein C2orf78 homolog [Ovis aries]","gi|548485231|ref|XM_005686456.1|",2731,0,"PREDICTED: Capra hircus chromosome 11 open reading frame, human C2orf78 (C11H2orf78), mRNA",".",".",".",".",".",".",".",".","pfam15442","DUF4629","Domain of unknown function (DUF4629). This domain family is found in eukaryotes, and is approximately 150 amino acids in length. There are two conserved sequence motifs: MHML and LGKK.",".",".",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","C3H12orf54",0.908885416,-64,"chr3:137584203-137607748:-","C3H12orf54","gi|803044306|ref|XP_004006451.2|",527,{"v":3e-64,"d":"3.00E-64"},"PREDICTED: uncharacterized protein C12orf54 homolog isoform X1 [Ovis aries]","gi|548465497|ref|XM_005680023.1|",702,0,"PREDICTED: Capra hircus chromosome 5 open reading frame, human C12orf54 (C5H12orf54), mRNA",".",".",".",".",".",".",".",".","pfam01226","Form_Nir_trans","Formate/nitrite transporter.",".",".",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","C14H16orf86",0.928875468,-64,"chr14:34462688-34464898:+","C14H16orf86","gi|803143523|ref|XP_012045362.1|",1353,0,"PREDICTED: uncharacterized protein C16orf86 homolog isoform X1 [Ovis aries]","gi|548503634|ref|XM_005692153.1|",1005,0,"PREDICTED: Capra hircus chromosome 18 open reading frame, human C16orf86 (C18H16orf86), transcript variant X2, mRNA",".",".",".",".",".",".",".",".","pfam13266","DUF4057","Protein of unknown function (DUF4057). This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 279 and 322 amino acids in length.",".",".",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","APOB",0.924696404,-64,"chr3:28578875-28618780:-","APOB","gi|803057156|ref|XP_012031328.1|",23903,0,"PREDICTED: apolipoprotein B-100 isoform X1 [Ovis aries]","gi|548487156|ref|XM_005687081.1|",13408,0,"PREDICTED: Capra hircus apolipoprotein B (APOB), mRNA","P04114",6810,0,"Apolipoprotein B-100",".",".",".",".","pfam01347","Vitellogenin_N","Lipoprotein amino terminal region. This family contains regions from: Vitellogenin, Microsomal triglyceride transfer protein and apolipoprotein B-100. These proteins are all involved in lipid transport. This family contains the LV1n chain from lipovitellin, that contains two structural domains.","GO:0048844|artery morphogenesis;GO:0007596|blood coagulation;GO:0071379|cellular response to prostaglandin stimulus;GO:0071356|cellular response to tumor necrosis factor;GO:0033344|cholesterol efflux;GO:0042632|cholesterol homeostasis;GO:0008203|cholesterol metabolic process;GO:0030301|cholesterol transport;GO:0009566|fertilization;GO:0001701|in utero embryonic development;GO:0050900|leukocyte migration;GO:0042158|lipoprotein biosynthetic process;GO:0042159|lipoprotein catabolic process;GO:0042157|lipoprotein metabolic process;GO:0042953|lipoprotein transport;GO:0034383|low-density lipoprotein particle clearance;GO:0034374|low-density lipoprotein particle remodeling;GO:0007399|nervous system development;GO:0007603|phototransduction, visible light;GO:0010886|positive regulation of cholesterol storage;GO:0010628|positive regulation of gene expression;GO:0010884|positive regulation of lipid storage;GO:0010744|positive regulation of macrophage derived foam cell differentiation;GO:0009791|post-embryonic development;GO:0006898|receptor-mediated endocytosis;GO:0045540|regulation of cholesterol biosynthetic process;GO:0009743|response to carbohydrate;GO:0032496|response to lipopolysaccharide;GO:0010269|response to selenium ion;GO:0009615|response to virus;GO:0001523|retinoid metabolic process;GO:0044281|small molecule metabolic process;GO:0030317|sperm motility;GO:0007283|spermatogenesis;GO:0019433|triglyceride catabolic process;GO:0006642|triglyceride mobilization;GO:0034379|very-low-density lipoprotein particle assembly;","GO:0015629|actin cytoskeleton;GO:0042627|chylomicron;GO:0034360|chylomicron remnant;GO:0030669|clathrin-coated endocytic vesicle membrane;GO:0005737|cytoplasm;GO:0005829|cytosol;GO:0005769|early endosome;GO:0071682|endocytic vesicle lumen;GO:0005788|endoplasmic reticulum lumen;GO:0005789|endoplasmic reticulum membrane;GO:0031904|endosome lumen;GO:0010008|endosome membrane;GO:0070062|extracellular exosome;GO:0005576|extracellular region;GO:0005615|extracellular space;GO:0005794|Golgi apparatus;GO:0034363|intermediate-density lipoprotein particle;GO:0043231|intracellular membrane-bounded organelle;GO:0034362|low-density lipoprotein particle;GO:0034359|mature chylomicron;GO:0043025|neuronal cell body;GO:0005886|plasma membrane;GO:0034361|very-low-density lipoprotein particle;","GO:0017127|cholesterol transporter activity;GO:0008201|heparin binding;GO:0035473|lipase binding;GO:0050750|low-density lipoprotein particle receptor binding;GO:0005543|phospholipid binding;","K14462","APOB; apolipoprotein B"]
["MYH15.1","chr1:171573069-171730662:-","ANXA10",0.916272979,-64,"chr2:111340962-111428246:-","ANXA10","gi|426220621|ref|XP_004004513.1|",1741,0,"PREDICTED: annexin A10 [Ovis aries]","gi|548476103|ref|XM_005683503.1|",1352,0,"PREDICTED: Capra hircus annexin A10 (ANXA10), mRNA","Q9UJ72",600,0,"Annexin A10",".",".",".",".","pfam00191","Annexin","Annexin. This family of annexins also includes giardin that has been shown to function as an annexin.",".","GO:0005739|mitochondrion;","GO:0005509|calcium ion binding;GO:0005544|calcium-dependent phospholipid binding;","K17097","ANXA10; annexin A10"]
["MYH15.1","chr1:171573069-171730662:-","AMZ1",0.94616388,-64,"chr24:40436042-40442797:-","AMZ1","gi|803197457|ref|XP_011960057.1|",1129,{"v":7e-149,"d":"7.00E-149"},"PREDICTED: archaemetzincin-1 isoform X4 [Ovis aries]","gi|555950356|ref|XM_005887319.1|",786,0,"PREDICTED: Bos mutus archaelysin family metallopeptidase 1 (AMZ1), mRNA","Q400G9",166,{"v":2e-43,"d":"2.00E-43"},"Archaemetzincin-1",".",".",".",".","pfam07998","Peptidase_M54","Peptidase family M54. This is a family of metallopeptidases. Two human proteins have been reported to degrade synthetic substrates and peptides.",".",".","GO:0008237|metallopeptidase activity;GO:0008270|zinc ion binding;","K06974","amzA, AMZ2, AMZ1; archaemetzincin [EC:3.4.-.-]"]
["MYH15.1","chr1:171573069-171730662:-","AMPD1",0.910747937,-64,"chr1:91064998-91087755:-","AMPD1","gi|426216307|ref|XP_004002406.1|",4115,0,"PREDICTED: AMP deaminase 1 isoform X1 [Ovis aries]","gi|548458523|ref|XM_005677842.1|",2347,0,"PREDICTED: Capra hircus adenosine monophosphate deaminase 1 (AMPD1), transcript variant X1, mRNA","P23109",1437,0,"AMP deaminase 1","SPBC106.04",555,0,"COG1816","pfam00962","A_deaminase","Adenosine/AMP deaminase.","GO:0032264|IMP salvage;GO:0055086|nucleobase-containing small molecule metabolic process;GO:0006144|purine nucleobase metabolic process;GO:0043101|purine-containing compound salvage;GO:0010033|response to organic substance;GO:0044281|small molecule metabolic process;","GO:0005829|cytosol;","GO:0003876|AMP deaminase activity;GO:0046872|metal ion binding;","K01490","AMPD; AMP deaminase [EC:3.5.4.6]"]
["MYH15.1","chr1:171573069-171730662:-","ALDH5A1",0.909269719,-64,"chr20:32027622-32053499:-","ALDH5A1","gi|803320425|ref|XP_012018422.1|",2400,0,"PREDICTED: succinate-semialdehyde dehydrogenase, mitochondrial isoform X2 [Ovis aries musimon]","gi|426251341|ref|XM_004019334.1|",4709,0,"PREDICTED: Ovis aries aldehyde dehydrogenase 5 family, member A1 (ALDH5A1), transcript variant X1, mRNA","P51650",809,0,"Succinate-semialdehyde dehydrogenase, mitochondrial","PA0265",548,{"v":1e-177,"d":"1.00E-177"},"COG1012","pfam00171","Aldedh","Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor. The family includes the following members: The prototypical members are the aldehyde dehydrogenases EC:1.2.1.3. Succinate-semialdehyde dehydrogenase EC:1.2.1.16. Lactaldehyde dehydrogenase EC:1.2.1.22. Benzaldehyde dehydrogenase EC:1.2.1.28. Methylmalonate-semialdehyde dehydrogenase EC:1.2.1.27. Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.9. Delta-1-pyrroline-5-carboxylate dehydrogenase EC: 1.5.1.12. Acetaldehyde dehydrogenase EC:1.2.1.10. Glutamate-5-semialdehyde dehydrogenase EC:1.2.1.41. This family also includes omega crystallin, an eye lens protein from squid and octopus that has little aldehyde dehydrogenase activity.","GO:0007417|central nervous system development;GO:0009450|gamma-aminobutyric acid catabolic process;GO:0055114|oxidation-reduction process;GO:0006105|succinate metabolic process;","GO:0005739|mitochondrion;","GO:0004029|aldehyde dehydrogenase (NAD) activity;GO:0031406|carboxylic acid binding;GO:0051287|NAD binding;GO:0004777|succinate-semialdehyde dehydrogenase (NAD+) activity;GO:0009013|succinate-semialdehyde dehydrogenase [NAD(P)+] activity;",".","."]
["NYAP1","chr24:35900853-35960797:-","AGFG2",0.92352495,-64,"chr24:35855415-35875942:-","AGFG2","gi|426254797|ref|XP_004021063.1|",1472,0,"PREDICTED: arf-GAP domain and FG repeat-containing protein 2 isoform X1 [Ovis aries]","gi|548520950|ref|XM_005697825.1|",2695,0,"PREDICTED: Capra hircus ArfGAP with FG repeats 2 (AGFG2), transcript variant X3, mRNA","O95081",501,{"v":1e-165,"d":"1.00E-165"},"Arf-GAP domain and FG repeat-containing protein 2","YNL204c",54.7,5e-07,"COG5347","pfam01412","ArfGap","Putative GTPase activating protein for Arf. Putative zinc fingers with GTPase activating proteins (GAPs) towards the small GTPase, Arf. The GAP of ARD1 stimulates GTPase hydrolysis for ARD1 but not ARFs.",".","GO:0016020|membrane;","GO:0005096|GTPase activator activity;GO:0046872|metal ion binding;",".","."]
["MYH15.1","chr1:171573069-171730662:-","ADCY1",0.912929707,-64,"chr4:76181792-76290252:-","ADCY1","gi|803216375|ref|XP_011968564.1|",4828,0,"PREDICTED: adenylate cyclase type 1 isoform X2 [Ovis aries musimon]","gi|594054142|ref|XM_006051280.1|",9006,0,"PREDICTED: Bubalus bubalis adenylate cyclase 1 (brain) (ADCY1), transcript variant X1, mRNA","P19754",63.9,3e-08,"Adenylate cyclase type 1","all0661",149,{"v":3e-36,"d":"3.00E-36"},"COG2114","pfam00211","Guanylate_cyc","Adenylate and Guanylate cyclase catalytic domain.","GO:0035556|intracellular signal transduction;GO:0042752|regulation of circadian rhythm;GO:0048511|rhythmic process;","GO:0005737|cytoplasm;GO:0016021|integral component of membrane;GO:0005886|plasma membrane;","GO:0004016|adenylate cyclase activity;GO:0005524|ATP binding;GO:0046872|metal ion binding;","K08041","ADCY1; adenylate cyclase 1 [EC:4.6.1.1]"]
["MYH15.1","chr1:171573069-171730662:-","ACTL7A",0.936625829,-64,"chr2:14399951-14401697:-","ACTL7A","gi|426219742|ref|XP_004004077.1|",2296,0,"PREDICTED: actin-like protein 7A [Ovis aries]","gi|594113434|ref|XM_006079406.1|",1493,0,"PREDICTED: Bubalus bubalis actin-like 7A (ACTL7A), mRNA","Q32KZ2",857,0,"Actin-like protein 7A","SPBC32H8.12c",322,{"v":4e-103,"d":"4.00E-103"},"COG5277","pfam00022","Actin","Actin.",".","GO:0005737|cytoplasm;GO:0005856|cytoskeleton;GO:0005794|Golgi apparatus;GO:0001673|male germ cell nucleus;GO:0031514|motile cilium;GO:0043234|protein complex;",".",".","."]
["MYH15.1","chr1:171573069-171730662:-","ABCG5",0.93020453,-64,"chr3:80200805-80232162:+","ABCG5","gi|426223755|ref|XP_004006039.1|",3370,0,"PREDICTED: ATP-binding cassette sub-family G member 5 [Ovis aries]","gi|548485477|ref|XM_005686547.1|",2237,0,"PREDICTED: Capra hircus ATP-binding cassette, sub-family G (WHITE), member 5 (ABCG5), mRNA","Q9H222",1081,0,"ATP-binding cassette sub-family G member 5",".",".",".",".","pfam00005","ABC_tran","ABC transporter. ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.","GO:0033344|cholesterol efflux;GO:0042632|cholesterol homeostasis;GO:0007588|excretion;GO:0030299|intestinal cholesterol absorption;GO:0045796|negative regulation of intestinal cholesterol absorption;GO:0010949|negative regulation of intestinal phytosterol absorption;GO:0042493|response to drug;GO:0010212|response to ionizing radiation;GO:0007584|response to nutrient;GO:0044281|small molecule metabolic process;GO:0015918|sterol transport;GO:0055085|transmembrane transport;","GO:0016324|apical plasma membrane;GO:0043190|ATP-binding cassette (ABC) transporter complex;GO:0005886|plasma membrane;GO:0043235|receptor complex;","GO:0005524|ATP binding;GO:0016887|ATPase activity;GO:0046982|protein heterodimerization activity;","K05683","ABCG5; ATP-binding cassette, subfamily G (WHITE), member 5 (sterolin 1)"]
["XLOC_017093","chr17:34053312-34054867:-","C2H2orf47",0.94395955,-64.9,"chr2:201229804-201240816:+","C2H2orf47","gi|426221312|ref|XP_004004854.1|",1339,0,"PREDICTED: uncharacterized protein C2orf47 homolog, mitochondrial [Ovis aries]","gi|556715852|ref|XM_005953791.1|",1165,0,"PREDICTED: Pantholops hodgsonii chromosome unknown open reading frame, human C2orf47 (LOC102328482), mRNA","A3KN05",487,{"v":7e-171,"d":"7.00E-171"},"Uncharacterized protein C2orf47 homolog, mitochondrial",".",".",".",".","pfam15258","FAM222A","Protein family of FAM222A. This protein family, FAM222A are a domain of unknown function. This family of proteins is found in eukaryotes and are typically between 411 and 562 amino acids in length. In humans, the gene encoding this protein domain lies in the position, chromosome 12 open reading frame 34.",".","GO:0005739|mitochondrion;",".",".","."]
["LOC101109655.1","chr1:10191483-10192228:+","STEAP2",0.941409187,-39.8,"chr4:74395870-74420792:+","STEAP2","gi|594104639|ref|XP_006081037.1|",2524,0,"PREDICTED: LOW QUALITY PROTEIN: STEAP family member 2, metalloreductase [Bubalus bubalis]","gi|548463589|ref|XM_005679305.1|",1806,0,"PREDICTED: Capra hircus STEAP family member 2, metalloreductase (STEAP2), transcript variant X1, mRNA","Q8NFT2",945,0,"Metalloreductase STEAP2","RSp1147",70.9,{"v":6e-13,"d":"6.00E-13"},"COG2085","pfam03807","F420_oxidored","NADP oxidoreductase coenzyme F420-dependent.","GO:0015677|copper ion import;GO:0006897|endocytosis;GO:0097461|ferric iron import into cell;GO:0006893|Golgi to plasma membrane transport;GO:0055072|iron ion homeostasis;GO:0055114|oxidation-reduction process;GO:0045055|regulated secretory pathway;GO:0009725|response to hormone;","GO:0005829|cytosol;GO:0005769|early endosome;GO:0010008|endosome membrane;GO:0030173|integral component of Golgi membrane;GO:0005887|integral component of plasma membrane;GO:0043231|intracellular membrane-bounded organelle;GO:0005886|plasma membrane;GO:0030140|trans-Golgi network transport vesicle;","GO:0008823|cupric reductase activity;GO:0052851|ferric-chelate reductase (NADPH) activity;GO:0046872|metal ion binding;GO:0005215|transporter activity;","K14738","STEAP2; metalloreductase STEAP2 [EC:1.16.1.-]"]
["LOC101109655.1","chr1:10191483-10192228:+","PHYHD1",0.912535025,-39.8,"chr3:7386479-7400984:-","PHYHD1","gi|426222940|ref|XP_004005637.1|",1550,0,"PREDICTED: phytanoyl-CoA dioxygenase domain-containing protein 1 isoform X2 [Ovis aries]","gi|556775248|ref|XM_005982684.1|",1184,0,"PREDICTED: Pantholops hodgsonii phytanoyl-CoA dioxygenase domain containing 1 (PHYHD1), transcript variant X1, mRNA","Q0IIB1",563,0,"Phytanoyl-CoA dioxygenase domain-containing protein 1","all4427",57,4e-08,"COG5285","pfam05721","PhyH","Phytanoyl-CoA dioxygenase (PhyH). This family is made up of several eukaryotic phytanoyl-CoA dioxygenase (PhyH) proteins, ectoine hydroxylases and a number of bacterial deoxygenases. PhyH is a peroxisomal enzyme catalyzing the first step of phytanic acid alpha-oxidation. PhyH deficiency causes Refsum's disease (RD) which is an inherited neurological syndrome biochemically characterized by the accumulation of phytanic acid in plasma and tissues.",".",".","GO:0051213|dioxygenase activity;GO:0046872|metal ion binding;",".","."]
["LOC101109655.1","chr1:10191483-10192228:+","PAFAH1B3",0.932699706,-41.4,"chr14:49926465-49929241:+","PAFAH1B3","gi|803147321|ref|XP_004015754.2|",1088,{"v":4e-147,"d":"4.00E-147"},"PREDICTED: platelet-activating factor acetylhydrolase IB subunit gamma isoform X1 [Ovis aries]","gi|548504704|ref|XM_005692565.1|",681,0,"PREDICTED: Capra hircus platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) (PAFAH1B3), transcript variant X1, mRNA","Q29460",420,{"v":9e-148,"d":"9.00E-148"},"Platelet-activating factor acetylhydrolase IB subunit gamma","all0976",53.5,1e-07,"COG2755","pfam13472","Lipase_GDSL_2","GDSL-like Lipase/Acylhydrolase family. This family of presumed lipases and related enzymes are similar to pfam00657.","GO:0007420|brain development;GO:0016042|lipid catabolic process;GO:0007283|spermatogenesis;","GO:0005737|cytoplasm;GO:0070062|extracellular exosome;GO:0016020|membrane;","GO:0003847|1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0047179|platelet-activating factor acetyltransferase activity;","K16795","PAFAH1B2_3; platelet-activating factor acetylhydrolase IB subunit beta/gamma [EC:3.1.1.47]"]
["LOC101109655.1","chr1:10191483-10192228:+","MUSTN1",0.941026672,-41.4,"chr19:48047363-48048805:+","MUSTN1","gi|426249403|ref|XP_004018439.1|",419,{"v":1e-48,"d":"1.00E-48"},"PREDICTED: musculoskeletal embryonic nuclear protein 1 [Ovis aries]","gi|556728361|ref|XM_005959852.1|",777,0,"PREDICTED: Pantholops hodgsonii transmembrane protein 110 (TMEM110), transcript variant X2, mRNA","Q32KU9",164,{"v":2e-49,"d":"2.00E-49"},"Musculoskeletal embryonic nuclear protein 1",".",".",".",".","pfam02959","Tax","HTLV Tax. Human T-cell leukaemia virus type I (HTLV-I) is the etiological agent for adult T-cell leukaemia (ATL), as well as for tropical spastic paraparesis (TSP) and HTLV-I associate myelopathy (HAM). A biological understanding of the involvement of HTLV-I and in ATL has focused significantly on the workings of the virally-encoded 40 kDa phospho-oncoprotein, Tax. Tax is a transcriptional activator. Its ability to modulate the expression and function of many cellular genes has been reasoned to be a major contributory mechanism explaining HTLV-I-mediated transformation of cells. In activating cellular gene expression, Tax impinges upon several cellular signal-transduction pathways, including those for CREB/ATF and NF-kappaB.",".","GO:0005634|nucleus;",".",".","."]
["LOC101109655.1","chr1:10191483-10192228:+","MED21",0.910096503,-41.4,"chr3:187331912-187342016:-","MED21","gi|562820790|ref|XP_006140333.1|",799,{"v":2e-104,"d":"2.00E-104"},"PREDICTED: mediator of RNA polymerase II transcription subunit 21 [Tupaia chinensis]","gi|548467251|ref|XM_005680730.1|",729,0,"PREDICTED: Capra hircus mediator complex subunit 21 (MED21), transcript variant X1, mRNA","Q2TBU8",291,{"v":4e-98,"d":"4.00E-98"},"Mediator of RNA polymerase II transcription subunit 21",".",".",".",".","pfam11221","Med21","Subunit 21 of Mediator complex. Med21 has been known as Srb7 in yeasts, hSrb7 in humans and Trap 19 in Drosophila. The heterodimer of the two subunits Med7 and Med21 appears to act as a hinge between the middle and the tail regions of Mediator.","GO:0001824|blastocyst development;GO:0045944|positive regulation of transcription from RNA polymerase II promoter;GO:0019827|stem cell population maintenance;GO:0006351|transcription, DNA-templated;","GO:0016592|mediator complex;","GO:0003713|transcription coactivator activity;","K15152","MED21, SRB7; mediator of RNA polymerase II transcription subunit 21"]
["LOC101109655.1","chr1:10191483-10192228:+","LAPTM4A",0.906021771,-41.4,"chr3:27683515-27700452:-","LAPTM4A","gi|625267463|ref|XP_007625238.1|",1038,{"v":8e-136,"d":"8.00E-136"},"PREDICTED: lysosomal-associated transmembrane protein 4A isoform X2 [Cricetulus griseus]","gi|548486646|ref|XM_005686976.1|",1369,0,"PREDICTED: Capra hircus lysosomal protein transmembrane 4 alpha (LAPTM4A), mRNA","Q6QRN8",397,{"v":7e-136,"d":"7.00E-136"},"Lysosomal-associated transmembrane protein 4A",".",".",".",".","pfam03821","Mtp","Golgi 4-transmembrane spanning transporter.","GO:0006810|transport;","GO:0005794|Golgi apparatus;GO:0016021|integral component of membrane;GO:0016020|membrane;",".","K12387","LAPTM; lysosomal-associated transmembrane protein"]
["LOC101109655.1","chr1:10191483-10192228:+","GNPDA1",0.954928123,-41.4,"chr5:50373117-50384377:-","GNPDA1","gi|426229770|ref|XP_004008956.1|",1470,0,"PREDICTED: glucosamine-6-phosphate isomerase 1 [Ovis aries]","gi|548474712|ref|XM_005683076.1|",2188,0,"PREDICTED: Capra hircus glucosamine-6-phosphate deaminase 1 (GNPDA1), transcript variant X1, mRNA","A4FV08",568,0,"Glucosamine-6-phosphate isomerase 1","PM0875",347,{"v":7e-112,"d":"7.00E-112"},"COG0363","pfam01182","Glucosamine_iso","Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase.","GO:0005975|carbohydrate metabolic process;GO:0006091|generation of precursor metabolites and energy;GO:0006043|glucosamine catabolic process;GO:0006044|N-acetylglucosamine metabolic process;","GO:0005737|cytoplasm;GO:0070062|extracellular exosome;","GO:0004342|glucosamine-6-phosphate deaminase activity;GO:0016787|hydrolase activity;","K02564","nagB, GNPDA; glucosamine-6-phosphate deaminase [EC:3.5.99.6]"]
["LOC101109655.1","chr1:10191483-10192228:+","COPS5",0.932107518,-41.4,"chr9:43872218-43889398:-","COPS5","gi|594092466|ref|XP_006069586.1|",1833,0,"PREDICTED: COP9 signalosome complex subunit 5 isoform X1 [Bubalus bubalis]","gi|548493258|ref|XM_005689038.1|",1299,0,"PREDICTED: Capra hircus COP9 signalosome subunit 5 (COPS5), mRNA","Q92905",547,0,"COP9 signalosome complex subunit 5","SPAC1687.13c",214,{"v":4e-65,"d":"4.00E-65"},"COG1310","pfam01398","JAB","JAB1/Mov34/MPN/PAD-1 ubiquitin protease. Members of this family are found in proteasome regulatory subunits, eukaryotic initiation factor 3 (eIF3) subunits and regulators of transcription factors. This family is also known as the MPN domain and PAD-1-like domain, JABP1 domain or JAMM domain. These are metalloenzymes that function as the ubiquitin isopeptidase/ deubiquitinase in the ubiquitin-based signaling and protein turnover pathways in eukaryotes. Versions of the domain in prokaryotic cognates of the ubiquitin-modification pathway are predicted to have a similar role.","GO:0010388|cullin deneddylation;GO:1990182|exosomal secretion;GO:0045944|positive regulation of transcription from RNA polymerase II promoter;GO:0000338|protein deneddylation;GO:0016579|protein deubiquitination;GO:0051726|regulation of cell cycle;GO:1903894|regulation of IRE1-mediated unfolded protein response;GO:0046328|regulation of JNK cascade;GO:0006366|transcription from RNA polymerase II promoter;GO:0006412|translation;GO:0006413|translational initiation;","GO:0030054|cell junction;GO:0008180|COP9 signalosome;GO:0005737|cytoplasm;GO:0005852|eukaryotic translation initiation factor 3 complex;GO:0005654|nucleoplasm;GO:0005634|nucleus;GO:0048471|perinuclear region of cytoplasm;GO:0008021|synaptic vesicle;","GO:0046872|metal ion binding;GO:0008237|metallopeptidase activity;GO:0003713|transcription coactivator activity;GO:0003743|translation initiation factor activity;GO:0004843|ubiquitin-specific protease activity;","K09613","COPS5, CSN5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]"]
["LOC101109655.1","chr1:10191483-10192228:+","COMMD9",0.946046465,-42.5,"chr15:64840220-64854206:-","COMMD9","gi|803162395|ref|XP_011951630.1|",1015,{"v":4e-134,"d":"4.00E-134"},"PREDICTED: COMM domain-containing protein 9 isoform X1 [Ovis aries]","gi|556774271|ref|XM_005982212.1|",1122,0,"PREDICTED: Pantholops hodgsonii COMM domain containing 9 (COMMD9), transcript variant X1, mRNA","Q2TBN5",389,{"v":2e-133,"d":"2.00E-133"},"COMM domain-containing protein 9",".",".",".",".","pfam07258","HCaRG","HCaRG protein. This family consists of several mammalian HCaRG(hypertension-related, calcium-regulated gene) proteins. HCaRG is negatively regulated by extracellular calcium concentration, and its basal mRNA levels are higher in hypertensive animals. HCaRG is a nuclear protein potentially involved in the control of cell proliferation.","GO:0006355|regulation of transcription, DNA-templated;GO:0006814|sodium ion transport;GO:0006351|transcription, DNA-templated;","GO:0016023|cytoplasmic membrane-bounded vesicle;GO:0005634|nucleus;",".",".","."]
["LOC101109655.1","chr1:10191483-10192228:+","CDKN2AIPNL",0.910414228,-42.5,"chr5:43267982-43274221:-","CDKN2AIPNL","gi|795414147|ref|XP_011945657.1|",265,{"v":4e-39,"d":"4.00E-39"},"PREDICTED: CDKN2AIP N-terminal-like protein isoform X1 [Cercocebus atys]","gi|548475251|ref|XM_005683309.1|",431,0,"PREDICTED: Capra hircus CDKN2A interacting protein N-terminal like (CDKN2AIPNL), partial mRNA",".",".",".",".",".",".",".",".","pfam11952","DUF3469","Protein of unknown function (DUF3469). This family of proteins are functionally uncharacterized. This protein is found in eukaryotes. Proteins in this family are typically between 108 to 439 amino acids in length.",".",".",".",".","."]
["LOC101109655.1","chr1:10191483-10192228:+","APOPT1",0.913323478,-43.2,"chr18:66780098-66805014:+","APOPT1","gi|803325635|ref|XP_012020978.1|",939,{"v":2e-122,"d":"2.00E-122"},"PREDICTED: apoptogenic protein 1, mitochondrial isoform X2 [Ovis aries musimon]","gi|594112621|ref|XM_006079033.1|",740,0,"PREDICTED: Bubalus bubalis apoptogenic 1, mitochondrial (APOPT1), transcript variant X2, mRNA","Q148E1",355,{"v":1e-119,"d":"1.00E-119"},"Apoptogenic protein 1, mitochondrial",".",".",".",".","pfam10231","DUF2315","Uncharacterized conserved protein (DUF2315). This is a family of small conserved proteins found from worms to humans. The function is not known.","GO:0097193|intrinsic apoptotic signaling pathway;GO:0043280|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0090200|positive regulation of release of cytochrome c from mitochondria;GO:0034393|positive regulation of smooth muscle cell apoptotic process;","GO:0005739|mitochondrion;",".",".","."]
["LOC101109655.1","chr1:10191483-10192228:+","ANAPC16",0.915576787,-43.2,"chr25:28060761-28071028:+","ANAPC16","gi|505844084|ref|XP_004615535.1|",450,{"v":4e-51,"d":"4.00E-51"},"PREDICTED: anaphase-promoting complex subunit 16 isoform X1 [Sorex araneus]","gi|556746156|ref|XM_005968490.1|",1224,0,"PREDICTED: Pantholops hodgsonii anaphase promoting complex subunit 16 (ANAPC16), transcript variant X2, mRNA","Q58DR0",176,{"v":3e-52,"d":"3.00E-52"},"Anaphase-promoting complex subunit 16",".",".",".",".","pfam03125","Sre","C. elegans Sre G protein-coupled chemoreceptor. Caenorhabditis elegans Sre proteins are candidate chemosensory receptors. There are four main recognized groups of such receptors: Odr-10, Sra, Sro, and Srg. Sre (this family), Sra pfam02117 and Srb pfam02175 comprise the Sra group. All of the above receptors are thought to be G protein-coupled seven transmembrane domain proteins. The existence of several different chemosensory receptors underlies the fact that in spite of having only 20-30 chemosensory neurones, C. elegans detects hundreds of different chemicals, with the ability to discern individual chemicals among combinations.","GO:0051301|cell division;GO:0007067|mitotic nuclear division;GO:0016567|protein ubiquitination;","GO:0005680|anaphase-promoting complex;GO:0005737|cytoplasm;",".",".","."]
["LOC101116211","chr2:36348838-36381116:-","TSPYL2",0.916190715,-60.7,"chrX:49826848-49833830:-","TSPYL2","gi|803324330|ref|XP_012020354.1|",1997,0,"PREDICTED: testis-specific Y-encoded-like protein 2 isoform X2 [Ovis aries musimon]","gi|528928888|ref|XM_869383.4|",2453,0,"PREDICTED: Bos taurus TSPY-like 2 (TSPYL2), mRNA","Q7TQI8",575,0,"Testis-specific Y-encoded-like protein 2",".",".",".",".","pfam00956","NAP","Nucleosome assembly protein (NAP). NAP proteins are involved in moving histones into the nucleus, nucleosome assembly and chromatin fluidity. They affect the transcription of many genes.","GO:0007049|cell cycle;GO:0016568|chromatin modification;GO:0030308|negative regulation of cell growth;GO:0008156|negative regulation of DNA replication;GO:0006334|nucleosome assembly;GO:0045859|regulation of protein kinase activity;GO:0006355|regulation of transcription, DNA-templated;GO:0006351|transcription, DNA-templated;","GO:0005813|centrosome;GO:0005737|cytoplasm;GO:0005730|nucleolus;GO:0005654|nucleoplasm;GO:0005634|nucleus;GO:0005886|plasma membrane;",".","K11285","TSPYL2, CINAP, DENTT; TSPY-like 2"]
["LOC101116211","chr2:36348838-36381116:-","TMEM64",0.967142917,-60.7,"chr9:86021697-86058270:+","TMEM64","gi|803107804|ref|XP_012039692.1|",1334,{"v":9e-166,"d":"9.00E-166"},"PREDICTED: transmembrane protein 64 isoform X1, partial [Ovis aries]","gi|594101658|ref|XM_006073852.1|",4203,0,"PREDICTED: Bubalus bubalis transmembrane protein 64 (TMEM64), mRNA","Q6YI46",375,{"v":3e-115,"d":"3.00E-115"},"Transmembrane protein 64","slr0305",61.6,2e-09,"COG0398","pfam09335","SNARE_assoc","SNARE associated Golgi protein. This is a family of SNARE associated Golgi proteins. The yeast member of this family localizes with the t-SNARE Tlg2.","GO:0051480|cytosolic calcium ion homeostasis;GO:0045780|positive regulation of bone resorption;GO:0045672|positive regulation of osteoclast differentiation;GO:0043462|regulation of ATPase activity;","GO:0005829|cytosol;GO:0005783|endoplasmic reticulum;GO:0016021|integral component of membrane;",".",".","."]
["LOC101116211","chr2:36348838-36381116:-","PSMC3IP",0.941676619,-60.7,"chr11:42083268-42088772:-","PSMC3IP","gi|296476450|tpg|DAA18565.1|",1330,{"v":1e-175,"d":"1.00E-175"},"TPA: PSMC3 interacting protein [Bos taurus]","gi|528996285|ref|XM_005220802.1|",1723,0,"PREDICTED: Bos taurus PSMC3 interacting protein (PSMC3IP), transcript variant X2, mRNA","O35047",397,{"v":2e-132,"d":"2.00E-132"},"Homologous-pairing protein 2 homolog",".",".",".",".","pfam07106","TBPIP","Tat binding protein 1(TBP-1)-interacting protein (TBPIP). This family consists of several eukaryotic TBP-1 interacting protein (TBPIP) sequences. TBP-1 has been demonstrated to interact with the human immunodeficiency virus type 1 (HIV-1) viral protein Tat, then modulate the essential replication process of HIV. In addition, TBP-1 has been shown to be a component of the 26S proteasome, a basic multiprotein complex that degrades ubiquitinated proteins in an ATP-dependent fashion. Human TBPIP interacts with human TBP-1 then modulates the inhibitory action of human TBP-1 on HIV-Tat-mediated transactivation.","GO:0006310|DNA recombination;GO:0051321|meiotic cell cycle;GO:1903506|regulation of nucleic acid-templated transcription;","GO:0005634|nucleus;","GO:0003677|DNA binding;GO:0030374|ligand-dependent nuclear receptor transcription coactivator activity;","K06695","PSMC3IP; 26S proteasome regulatory subunit, ATPase 3, interacting protein"]
["LOC101116211","chr2:36348838-36381116:-","LOC101119659",0.948116911,-60.7,"chr12:70149540-70150703:+","LOC101119659","gi|803129401|ref|XP_004013962.2|",1257,{"v":1e-171,"d":"1.00E-171"},"PREDICTED: nascent polypeptide-associated complex subunit alpha-like isoform X1 [Ovis aries]","gi|548466126|ref|XM_005680329.1|",905,0,"PREDICTED: Capra hircus nascent polypeptide-associated complex subunit alpha-like (LOC102185811), transcript variant X2, mRNA","Q60817",340,{"v":7e-116,"d":"7.00E-116"},"Nascent polypeptide-associated complex subunit alpha","SPBC25H2.05",107,{"v":7e-27,"d":"7.00E-27"},"COG1308","pfam01849","NAC","NAC domain.","GO:0003231|cardiac ventricle development;GO:0061384|heart trabecula morphogenesis;GO:0010664|negative regulation of striated muscle cell apoptotic process;GO:1901227|negative regulation of transcription from RNA polymerase II promoter involved in heart development;GO:2000138|positive regulation of cell proliferation involved in heart morphogenesis;GO:0048633|positive regulation of skeletal muscle tissue growth;GO:1901228|positive regulation of transcription from RNA polymerase II promoter involved in heart development;GO:0015031|protein transport;GO:0048742|regulation of skeletal muscle fiber development;GO:0043403|skeletal muscle tissue regeneration;GO:0006351|transcription, DNA-templated;","GO:0005737|cytoplasm;GO:0005634|nucleus;","GO:0003677|DNA binding;",".","."]
["LOC101116211","chr2:36348838-36381116:-","LOC101106071",0.915339221,-60.7,"chr3:179200771-179202277:+","LOC101106071","gi|803318530|ref|XP_012017495.1|",1154,{"v":2e-152,"d":"2.00E-152"},"PREDICTED: apolipoprotein L2-like isoform X1 [Ovis aries musimon]","gi|556764496|ref|XR_319266.1|",1218,0,"PREDICTED: Pantholops hodgsonii apolipoprotein L2-like (LOC102336975), misc_RNA","O95236",120,{"v":1e-28,"d":"1.00E-28"},"Apolipoprotein L3",".",".",".",".","pfam05461","ApoL","Apolipoprotein L. Apo L belongs to the high density lipoprotein family that plays a central role in cholesterol transport. The cholesterol content of membranes is important in cellular processes such as modulating gene transcription and signal transduction both in the adult brain and during neurodevelopment. There are six apo L genes located in close proximity to each other on chromosome 22q12 in humans. 22q12 is a confirmed high-susceptibility locus for schizophrenia and close to the region associated with velocardiofacial syndrome that includes symptoms of schizophrenia.","GO:0006954|inflammatory response;GO:0042157|lipoprotein metabolic process;GO:0043123|positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007165|signal transduction;","GO:0005737|cytoplasm;GO:0005576|extracellular region;GO:0016020|membrane;","GO:0008289|lipid binding;GO:0005319|lipid transporter activity;GO:0004871|signal transducer activity;","K14480","APOL; apolipoprotein L"]
["LOC101116211","chr2:36348838-36381116:-","DYNLL2",0.918621566,-60.7,"chr11:8409213-8427132:+","DYNLL2","gi|676281237|gb|KFO35006.1|",509,{"v":3e-57,"d":"3.00E-57"},"Dynein light chain 2, cytoplasmic [Fukomys damarensis]","gi|164519005|ref|NM_001113303.1|",2116,0,"Bos taurus dynein, light chain, LC8-type 2 (DYNLL2), mRNA","Q78P75",187,{"v":1e-54,"d":"1.00E-54"},"Dynein light chain 2, cytoplasmic",".",".",".",".","pfam01221","Dynein_light","Dynein light chain type 1.","GO:0007017|microtubule-based process;GO:0008039|synaptic target recognition;GO:0006810|transport;","GO:0005813|centrosome;GO:0005737|cytoplasm;GO:0030286|dynein complex;GO:0016020|membrane;GO:0005874|microtubule;GO:0016459|myosin complex;GO:0005634|nucleus;","GO:0008092|cytoskeletal protein binding;GO:0003774|motor activity;","K10418","DYNLL; dynein light chain LC8-type"]
["LOC101116211","chr2:36348838-36381116:-","DLEC1",0.968720853,-60.7,"chr19:11443178-11529959:+","DLEC1","gi|803186881|ref|XP_011955712.1|",8610,0,"PREDICTED: deleted in lung and esophageal cancer protein 1 isoform X1 [Ovis aries]","gi|556761260|ref|XM_005975879.1|",4540,0,"PREDICTED: Pantholops hodgsonii deleted in lung and esophageal cancer 1 (DLEC1), mRNA","Q9Y238",2432,0,"Deleted in lung and esophageal cancer protein 1",".",".",".",".","pfam15498","Dendrin","Nephrin and CD2AP-binding protein, Dendrin. Dendrin is a family of eukaryotic proteins found in the podocytes of the kidneys. Dendrin, originally identified in telencephalic dendrites, is a constituent of the slit diaphragm, SD, complex of podocytes, where it directly binds to nephrin and CD2AP. Kidney podocytes and their slit diaphragms (SDs) form the final barrier to urinary protein loss. SD proteins also participate in intracellular signalling pathways. Dendrin appears to prevent programmed cell death (apoptosis) through its binding to nephrin. The SD protein nephrin serves as a component of a signalling complex that directly links podocyte junctional integrity to actin cytoskeletal dynamics. Thus, dendrin is identified as an SD family with proapoptotic signalling properties that accumulates in the podocyte nucleus in response to glomerular injury.","GO:0008285|negative regulation of cell proliferation;","GO:0005737|cytoplasm;",".",".","."]
["LOC101116211","chr2:36348838-36381116:-","COL13A1",0.902677806,-60.7,"chr25:25869084-25959788:+","COL13A1","gi|803241662|ref|XP_011980929.1|",599,{"v":4e-62,"d":"4.00E-62"},"PREDICTED: collagen alpha-1(XIII) chain isoform X26 [Ovis aries musimon]","gi|594628437|ref|XM_007167748.1|",1623,0,"PREDICTED: Balaenoptera acutorostrata scammoni collagen, type XIII, alpha 1 (COL13A1), transcript variant X2, mRNA","Q5TAT6",175,{"v":7e-44,"d":"7.00E-44"},"Collagen alpha-1(XIII) chain",".",".",".",".","pfam01391","Collagen","Collagen triple helix repeat (20 copies). Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxyproline. Collagens are post translationally modified by proline hydroxylase to form the hydroxyproline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure.","GO:0030154|cell differentiation;GO:0007160|cell-matrix adhesion;GO:0001958|endochondral ossification;GO:0001763|morphogenesis of a branching structure;GO:0016337|single organismal cell-cell adhesion;","GO:0005911|cell-cell junction;GO:0005581|collagen trimer;GO:0016021|integral component of membrane;GO:0005886|plasma membrane;","GO:0008201|heparin binding;","K16617","COL13A; collagen, type XIII, alpha"]
["LOC101116211","chr2:36348838-36381116:-","CACYBP",0.914570724,-60.7,"chr12:54175444-54186100:+","CACYBP","gi|426239923|ref|XP_004013866.1|",1202,{"v":5e-163,"d":"5.00E-163"},"PREDICTED: calcyclin-binding protein isoform X1 [Ovis aries]","gi|548499328|ref|XM_005690906.1|",1130,0,"PREDICTED: Capra hircus calcyclin binding protein (CACYBP), transcript variant X1, mRNA","Q3T168",463,{"v":5e-163,"d":"5.00E-163"},"Calcyclin-binding protein",".",".",".",".","pfam09032","Siah-Interact_N","Siah interacting protein, N terminal. The N terminal domain of Siah interacting protein (SIP) adopts a helical hairpin structure with a hydrophobic core stabilized by a classic knobs-and-holes arrangement of side chains contributed by the two amphipathic helices. Little is known about this domain's function, except that it is crucial for interactions with Siah. It has also been hypothesised that SIP can dimerise through this N terminal domain.",".","GO:0030877|beta-catenin destruction complex;GO:0070062|extracellular exosome;GO:0005641|nuclear envelope lumen;GO:0005654|nucleoplasm;",".","K04507","CACYBP, SIP; calcyclin binding protein"]
["LOC101116211","chr2:36348838-36381116:-","C6H4orf36",0.910789729,-60.7,"chr6:101287236-101304031:-","C6H4orf36","gi|426232280|ref|XP_004010161.1|",533,{"v":2e-60,"d":"2.00E-60"},"PREDICTED: uncharacterized protein C4orf36 homolog [Ovis aries]","gi|594062789|ref|XR_327303.1|",483,0,"PREDICTED: Bubalus bubalis solute carrier family 10 member 6-like (LOC102397830), transcript variant X8, misc_RNA",".",".",".",".",".",".",".",".","pfam15022","DUF4522","Protein of unknown function (DUF4522). This family of proteins is functionally uncharacterized. This family of proteins is found in mammals. In human this protein is known as C4orf36.",".",".",".",".","."]
["LOC101116211","chr2:36348838-36381116:-","AKAP8L",0.923235784,-60.7,"chr5:7480182-7510868:+","AKAP8L","gi|426228852|ref|XP_004008510.1|",2411,0,"PREDICTED: A-kinase anchor protein 8-like isoform X1 [Ovis aries]","gi|594046628|ref|XM_006047689.1|",1934,0,"PREDICTED: Bubalus bubalis A kinase (PRKA) anchor protein 8-like (AKAP8L), transcript variant X1, mRNA","Q9ULX6",63.9,3e-09,"A-kinase anchor protein 8-like",".",".",".",".","pfam04988","AKAP95","A-kinase anchoring protein 95 (AKAP95). A-kinase (or PKA)-anchoring protein AKAP95 is implicated in mitotic chromosome condensation by acting as a targeting molecule for the condensin complex. The protein contains two zinc fingers which are thought to mediate the binding of AKAP95 to DNA.",".","GO:0005737|cytoplasm;GO:0016363|nuclear matrix;GO:0005654|nucleoplasm;GO:0005634|nucleus;","GO:0017151|DEAD/H-box RNA helicase binding;GO:0003677|DNA binding;GO:0046872|metal ion binding;GO:0044822|poly(A) RNA binding;","K15978","AKAP8L, HA95; A-kinase anchor protein 8-like protein"]