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{"sheet":"TableS1","index":0,"n_rows":95,"n_cols":5,"rows_kept":95,"flags":["formulas_cached_only"]}
["1. Estrogen-responsive protein Efp controls cell cycle and breast tumors growth "]
["CCNB2","Cyclin B2","NM_004701","Hs.194698",9133]
["CDK6","Cyclin-dependent kinase 6","NM_001259","Hs.119882",1021]
["ESR1","Estrogen receptor 1","NM_000125","Hs.208124",2099]
["ESR1","Estrogen receptor 1","X74439","Hs.652547",2099]
["SFN","Stratifin","NM_006142","Hs.523718",2810]
["SMURF1","SMAD specific E3 ubiquitin protein ligase 1","NM_020429 NM_181349","Hs.189329",57154]
["TP53","Tumor protein p53 (Li-Fraumeni syndrome)","NM_000546","Hs.654481",7157]
["TRIM25","Tripartite motif-containing 25","NM_005082","Hs.528952",7706]
[]
[]
["2. ER-associated degradation (ERAD) Pathway "]
["CANX","Calnexin","NM_001746 NM_001024649","Hs.567968",821]
["CUL1","Cullin 1","NM_003592","Hs.146806",8454]
["EDEM1","ER degradation enhancer, mannosidase alpha-like 1","NM_014674","Hs.224616",9695]
["FBXO2","F-box protein 2","NM_012168","Hs.132753",26232]
["GANAB","Glucosidase, alpha; neutral AB","NM_198335 NM_198334","Hs.595071",23193]
["GCS1","Glucosidase I","NM_006302","Hs.516119",7841]
["LEMD3","LEM domain containing 3","NM_014319","Hs.505905",23592]
["MAN2A2","Mannosidase, alpha, class 2A, member 2","NM_006122","Hs.116459",4122]
["RBX1","Ring-box 1","NM_014248","Hs.474949",9978]
["SAE1","SUMO1 activating enzyme subunit 1","NM_005500","Hs.515500",10055]
["SEC61A1","Sec61 alpha 1 subunit (S. cerevisiae)","NM_013336","Hs.518236",29927]
["SKP1A","S-phase kinase-associated protein 1A (p19A)","NM_006930 NM_170679","Hs.171626",6500]
["SKP1A","S-phase kinase-associated protein 1A (p19A)","BM547085","Hs.643015",6500]
["UBE2I","Ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)","NM_194259 NM_003345 NM_194261 NM_194260","Hs.302903",7329]
["UGCGL1","UDP-glucose ceramide glucosyltransferase-like 1","NM_001025777 NM_020120","Hs.34180",56886]
[]
["3. BRCA1-dependent Ub-ligase activity "]
["BARD1","BRCA1 associated RING domain 1","NM_000465","Hs.591642",580]
["BRCA1","Breast cancer 1, early onset","NM_007295 NM_007294 NM_007296 NM_007302 NM_007297 NM_007299 NM_007300 NM_007304 NM_007303 NM_007305 NM_007298","Hs.194143",672]
["FANCA","Fanconi anemia, complementation group A","NM_000135 NM_001018112","Hs.567267",2175]
["FANCC","Fanconi anemia, complementation group C","NM_000136","Hs.494529",2176]
["FANCC","Fanconi anemia, complementation group C","BC006303","Hs.656658",2176]
["FANCC","Fanconi anemia, complementation group C","BC034271","Hs.672362",2176]
["FANCD2","Fanconi anemia, complementation group D2","NM_033084 NM_001018115","Hs.208388",2177]
["FANCE","Fanconi anemia, complementation group E","NM_021922","Hs.302003",2178]
["FANCF","Fanconi anemia, complementation group F","NM_022725","Hs.694767",2188]
["FANCG","Fanconi anemia, complementation group G","NM_004629","Hs.591084",2189]
[]
["4. Cell Cycle: G1/S Check Point "]
["APBA2BP","Amyloid beta (A4) precursor protein-binding, family A, member 2 binding protein","NM_031232 NM_031231","Hs.516986",63941]
["ATR","Ataxia telangiectasia and Rad3 related","NM_001184","Hs.271791",545]
["CCNA1","Cyclin A1","NM_003914","Hs.417050",8900]
["CCND1","Cyclin D1","NM_053056","Hs.523852",595]
["CCNE1","Cyclin E1","NM_001238 NM_057182","Hs.244723",898]
["CDC2","Cell division cycle 2, G1 to S and G2 to M","NM_001786 NM_033379","Hs.334562",983]
["CDC25A","Cell division cycle 25 homolog A (S. pombe)","NM_001789 NM_201567","Hs.437705",993]
["CDK2","Cyclin-dependent kinase 2","NM_001798 NM_052827","Hs.19192",1017]
["CDK4","Cyclin-dependent kinase 4","NM_000075","Hs.95577",1019]
["CDK6","Cyclin-dependent kinase 6","NM_001259","Hs.119882",1021]
["CDKN1A","Cyclin-dependent kinase inhibitor 1A (p21, Cip1)","NM_078467 NM_000389","Hs.370771",1026]
["CDKN1B","Cyclin-dependent kinase inhibitor 1B (p27, Kip1)","NM_004064","Hs.238990",1027]
["CDKN2A","Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)","NM_058197 NM_000077 NM_058195","Hs.512599",1029]
["CDKN2B","Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)","NM_078487 NM_004936","Hs.72901",1030]
["DHFR","Dihydrofolate reductase","NM_000791","Hs.648635",1719]
["DHFR","Dihydrofolate reductase","BM011996","Hs.654551",1719]
["ELAC1","ElaC homolog 1 (E. coli)","NM_018696","Hs.657360",55520]
["GSK3B","Glycogen synthase kinase 3 beta","NM_002093","Hs.445733",2932]
["HDAC9","Histone deacetylase 9","NM_178423 NM_178425 NM_014707 NM_058176 NM_058177","Hs.196054",9734]
["MTTP","Microsomal triglyceride transfer protein","NM_000253","Hs.195799",4547]
["RB1","Retinoblastoma 1 (including osteosarcoma)","NM_000321","Hs.408528",5925]
["SKP2","S-phase kinase-associated protein 2 (p45)","NM_005983 NM_032637","Hs.23348",6502]
["SMAD3","SMAD family member 3","BU686912","Hs.618504",4088]
["SMAD3","SMAD family member 3","NM_005902","Hs.696294",4088]
["TFDP1","Transcription factor Dp-1","NM_007111","Hs.79353",7027]
["TGFB1","Transforming growth factor, beta 1","NM_000660","Hs.645227",7040]
["TP53","Tumor protein p53 (Li-Fraumeni syndrome)","NM_000546","Hs.654481",7157]
["-","Transcribed locus","AA032275","Hs.36915",4088]
[]
["5. Cell Cycle: G2/M Checkpoint "]
["ATR","Ataxia telangiectasia and Rad3 related","NM_001184","Hs.271791",545]
["BRCA1","Breast cancer 1, early onset","NM_007295 NM_007294 NM_007296 NM_007302 NM_007297 NM_007299 NM_007300 NM_007304 NM_007303 NM_007305 NM_007298","Hs.194143",672]
["CCNB1","Cyclin B1","NM_031966","Hs.23960",891]
["CDC2","Cell division cycle 2, G1 to S and G2 to M","NM_001786 NM_033379","Hs.334562",983]
["CDC34","Cell division cycle 34 homolog (S. cerevisiae)","NM_004359","Hs.514997",997]
["CDKN1A","Cyclin-dependent kinase inhibitor 1A (p21, Cip1)","NM_078467 NM_000389","Hs.370771",1026]
["CDKN2D","Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)","NM_001800 NM_079421","Hs.435051",1032]
["CHEK1","CHK1 checkpoint homolog (S. pombe)","NM_001274","Hs.24529",1111]
["CHEK2","CHK2 checkpoint homolog (S. pombe)","NM_001005735 NM_007194 NM_145862","Hs.291363",11200]
["CHEK2","CHK2 checkpoint homolog (S. pombe)","BP420084","Hs.505297",11200]
["EP300","E1A binding protein p300","NM_001429","Hs.517517",2033]
["EP300","E1A binding protein p300","AI470276","Hs.655211",2033]
["GADD45A","Growth arrest and DNA-damage-inducible, alpha","NM_001924","Hs.80409",1647]
["MDM2","Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse)","NM_002392 NM_006878 NM_006881 NM_006882 NM_006879","Hs.567303",4193]
["MYT1","Myelin transcription factor 1","NM_004535","Hs.279562",4661]
["PLK1","Polo-like kinase 1 (Drosophila)","NM_005030","Hs.592049",5347]
["PRKDC","Protein kinase, DNA-activated, catalytic polypeptide","NM_006904 NM_001081640","Hs.695981",5591]
["RASGRF1","Ras protein-specific guanine nucleotide-releasing factor 1","NM_002891 NM_153815","Hs.591111",5923]
["RPS6KA1","Ribosomal protein S6 kinase, 90kDa, polypeptide 1","NM_002953 NM_001006665","Hs.149957",6195]
["TP53","Tumor protein p53 (Li-Fraumeni syndrome)","NM_000546","Hs.654481",7157]
["WEE1","WEE1 homolog (S. pombe)","NM_003390","Hs.249441",7465]
["YWHAH","Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide","NM_003405","Hs.226755",7533]
["YWHAQ","Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide","NM_006826","Hs.74405",10971]
["-","Transcribed locus","BG261310","Hs.491682",5591]