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<rdf:Description rdf:about="#metaid_0000308">            <bqmodel:isDescribedBy>              <rdf:Bag>                <rdf:li rdf:resource="urn:miriam:omim:611223"/>              </rdf:Bag>            </bqmodel:isDescribedBy>            <bqbiol:isVersionOf>              <rdf:Bag>                <rdf:li rdf:resource="urn:miriam:uniprot:Q9Y243"/>              </rdf:Bag>            </bqbiol:isVersionOf>          </rdf:Description>        </rdf:RDF>      </annotation>    </species>    <species metaid="metaid_0000309" id="RsD" name="RasGDP" compartment="membrane" initialAmount="95.7">      <annotation>        <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">          <rdf:Description rdf:about="#metaid_0000309">            <bqbiol:hasPart>              <rdf:Bag>                <rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A17552"/>                <rdf:li rdf:resource="urn:miriam:uniprot:P01112"/>              </rdf:Bag>            </bqbiol:hasPart>            <bqbiol:isVersionOf>              <rdf:Bag>                <rdf:li rdf:resource="urn:miriam:interpro:IPR013753"/>              </rdf:Bag>            </bqbiol:isVersionOf>          </rdf:Description>        </rdf:RDF>      </annotation>    </species>    <species metaid="metaid_0000310" id="RsT" name="RasGTP" compartment="membrane" initialAmount="0">      <annotation>        <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">          <rdf:Description rdf:about="#metaid_0000310">            <bqbiol:hasPart>              <rdf:Bag>                <rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A15996"/>                <rdf:li rdf:resource="urn:miriam:uniprot:P01112"/>              </rdf:Bag>            </bqbiol:hasPart>            <bqbiol:hasVersion>              <rdf:Bag>                <rdf:li rdf:resource="urn:miriam:interpro:IPR013753"/>              </rdf:Bag>            </bqbiol:hasVersion>          </rdf:Description>        </rdf:RDF>      </annotation>    </species>    <species metaid="metaid_0000311" id="SigRP" name="Sum RasGAP_p" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000312" id="Raf" name="Raf" compartment="membrane" initialAmount="743">      <annotation>        <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">          <rdf:Description rdf:about="#metaid_0000312">            <bqbiol:isVersionOf>              <rdf:Bag>                <rdf:li rdf:resource="null:P04049"/>              </rdf:Bag>            </bqbiol:isVersionOf>            <bqmodel:isDescribedBy>              <rdf:Bag>                <rdf:li rdf:resource="null:164760"/>              </rdf:Bag>            </bqmodel:isDescribedBy>          </rdf:Description>        </rdf:RDF>      </annotation>    </species>    <species metaid="metaid_0000313" id="Rafstar" name="Raf*" compartment="membrane" initialAmount="0">      <annotation>        <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">          <rdf:Description rdf:about="#metaid_0000313">            <bqbiol:isVersionOf>              <rdf:Bag>                <rdf:li rdf:resource="null:P04049"/>              </rdf:Bag>            </bqbiol:isVersionOf>            <bqmodel:isDescribedBy>              <rdf:Bag>                <rdf:li rdf:resource="null:164760"/>              </rdf:Bag>            </bqmodel:isDescribedBy>          </rdf:Description>        </rdf:RDF>      </annotation>    </species>    <species metaid="metaid_0000314" id="MEK" name="MEK" compartment="membrane" initialAmount="772">      <annotation>        <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">          <rdf:Description rdf:about="#metaid_0000314">            <bqmodel:isDescribedBy>              <rdf:Bag>       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rdf:about="#metaid_0000316">            <bqmodel:isDescribedBy>              <rdf:Bag>                <rdf:li rdf:resource="urn:miriam:omim:176948"/>              </rdf:Bag>            </bqmodel:isDescribedBy>            <bqbiol:isVersionOf>              <rdf:Bag>                <rdf:li rdf:resource="urn:miriam:uniprot:P28482"/>              </rdf:Bag>            </bqbiol:isVersionOf>          </rdf:Description>        </rdf:RDF>      </annotation>    </species>    <species metaid="metaid_0000317" id="ERKstar" name="ERK*" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000318" id="OP" name="SOS_p" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000319" id="AP" name="Gab1_p" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000320" id="A_SigG_O" name="Gab1_SumGrb2-SOS" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000321" id="SigA_G" name="Sum PIP3-Gab1-Grb2" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000322" id="SigA_G_O" name="Sum PIP3-Gab1-Grb2_SOS" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000323" id="SigO" name="Sum SOS" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000324" id="E13" name="ErbB1-ErbB3" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000325" id="E14" name="ErbB1-ErbB4" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000326" id="E13P" name="ErbB1-ErbB3_p" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000327" id="E14P" name="ErbB1-ErbB3_p" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000328" id="E13G" name="E13-Grb2" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000329" id="E13S" name="E13-Shc" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000330" id="E13I" name="E13-PI-3K" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000331" id="E13R" name="E13-RasGAP" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000332" id="E14G" name="E14-Grb2" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000333" id="E14S" name="E14-Shc" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000334" id="E14I" name="E14-PI-3K" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000335" id="E14R" name="E14-RasGAP" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000336" id="T" name="PTP-1B" compartment="membrane" initialAmount="500">      <annotation>        <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">          <rdf:Description rdf:about="#metaid_0000336">            <bqmodel:isDescribedBy>              <rdf:Bag>                <rdf:li rdf:resource="urn:miriam:omim:176885"/>              </rdf:Bag>            </bqmodel:isDescribedBy>            <bqbiol:isVersionOf>              <rdf:Bag>                <rdf:li rdf:resource="urn:miriam:uniprot:P18031"/>              </rdf:Bag>            </bqbiol:isVersionOf>          </rdf:Description>        </rdf:RDF>      </annotation>    </species>    <species metaid="metaid_0000337" id="E11T" name="E11-PTP-1B" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000338" id="E12T" name="E12-PTP-1B" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000339" id="E23T" name="E23-PTP-1B" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000340" id="E34T" name="E34-PTP-1B" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000341" id="E24T" name="E24-PTP-1B" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000342" id="E44T" name="E44-PTP-1B" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000343" id="E13T" name="E13-PTP-1B" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000344" id="E14T" name="E14-PTP-1B" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000345" id="SigT" name="Sig-PTP-1B" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000346" id="E1_PT" name="E1_p-PTP-1B" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000347" id="E2_PT" name="E2_p-PTP-1B" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000348" id="E4_PT" name="E4_p-PTP-1B" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000349" id="E_E1_PT" name="E_E1_p-PTP-1B" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000350" id="H_E4_PT" name="H_E4_p-PTP-1B" compartment="membrane" initialAmount="0"/> 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</rdf:RDF>      </annotation>    </species>    <species metaid="metaid_0000354" id="H" name="HRG" compartment="membrane" initialAmount="10">      <annotation>        <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">          <rdf:Description rdf:about="#metaid_0000354">            <bqbiol:isVersionOf>              <rdf:Bag>                <rdf:li rdf:resource="urn:miriam:uniprot:Q02297"/>                <rdf:li rdf:resource="urn:miriam:omim:142445"/>              </rdf:Bag>            </bqbiol:isVersionOf>          </rdf:Description>        </rdf:RDF>      </annotation>    </species>    <species metaid="metaid_0000355" id="fint" name="fint" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000356" id="pERK" name="p_ERK" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000357" id="ERK_MEKstar" name="ERK-MEK*" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000358" id="pERK_MEKstar" name="p_ERK-MEK*" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000359" id="pERK_ERKpase" name="p_ERK-ERKpase" compartment="membrane" initialAmount="0"/>    <species metaid="metaid_0000360" id="ERKpase" name="ERKpase" compartment="membrane" initialAmount="0">      <annotation>        <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">          <rdf:Description rdf:about="#metaid_0000360">            <bqmodel:isDescribedBy>              <rdf:Bag>                <rdf:li rdf:resource="urn:miriam:omim:602747"/>                <rdf:li rdf:resource="urn:miriam:omim:600714"/>                <rdf:li rdf:resource="urn:miriam:omim:602748"/>              </rdf:Bag>            </bqmodel:isDescribedBy>            <bqbiol:isVersionOf>              <rdf:Bag>                <rdf:li rdf:resource="urn:miriam:uniprot:P28562"/>                <rdf:li rdf:resource="urn:miriam:uniprot:Q13115"/>                <rdf:li rdf:resource="urn:miriam:uniprot:Q16828"/>              </rdf:Bag>            </bqbiol:isVersionOf>          </rdf:Description>        </rdf:RDF>      </annotation>    </species>    <species metaid="metaid_0000361" id="ERKstar_ERKpase" name="ERK*-ERKpase" compartment="membrane" initialAmount="35"/>    <species metaid="metaid_0000464" id="norm_Akt_star" name="normalized Akt*" compartment="membrane" boundaryCondition="true"/>    <species metaid="metaid_0000465" id="norm_Erk_star" name="normalized Erk*" compartment="membrane" boundaryCondition="true"/>  </listOfSpecies>  <listOfParameters>    <parameter metaid="metaid_0000003" id="ErbB1_Abund" name="ErbB1_Abund" value="274"/>    <parameter metaid="metaid_0000004" id="ErbB2_Abund" name="ErbB2_Abund" value="158"/>    <parameter metaid="metaid_0000005" id="ErbB3_Abund" name="ErbB3_Abund" value="294"/>    <parameter metaid="metaid_0000006" id="ErbB4_Abund" name="ErbB4_Abund" value="399"/>    <parameter metaid="metaid_0000007" id="Grb2_Abund" name="Grb2_Abund" value="82.4"/>    <parameter metaid="metaid_0000008" id="Shc_Abund" name="Shc_Abund" value="11.5"/>    <parameter metaid="metaid_0000009" id="PI3K_Abund" name="PI3K_Abund" value="46.4"/>    <parameter metaid="metaid_0000010" id="RasGAP_Abund" name="RasGAP_Abund" value="93.6"/>    <parameter metaid="metaid_0000011" id="SOS_Abund" name="SOS_Abund" value="82.3"/>    <parameter metaid="metaid_0000012" id="Gab1_Abund" name="Gab1_Abund" value="43.1"/>    <parameter metaid="metaid_0000013" id="PIP2_Abund" name="PIP2_Abund" value="197"/>    <parameter metaid="metaid_0000014" id="Akt_Abund" name="Akt_Abund" value="444.2921"/>    <parameter metaid="metaid_0000015" id="Ras_Abund" name="Ras_Abund" value="95.7"/>    <parameter metaid="metaid_0000016" id="Raf_Abund" name="Raf_Abund" value="743"/>    <parameter metaid="metaid_0000017" id="MEK_Abund" name="MEK_Abund" value="772"/>    <parameter metaid="metaid_0000018" id="ERK_Abund" name="ERK_Abund" value="749.9716"/>    <parameter metaid="metaid_0000019" id="VmaxPY" name="VmaxPY" value="223.8776"/>    <parameter metaid="metaid_0000020" id="KmPY" name="KmPY" value="486.1398"/>    <parameter metaid="metaid_0000021" id="kdeg" name="kdeg" value="0.0259"/>    <parameter metaid="metaid_0000022" id="kf47" name="kf47" value="24.6048"/>    <parameter metaid="metaid_0000023" id="Vmaxr47" name="Vmaxr47" value="590.5058"/>    <parameter metaid="metaid_0000024" id="Kmf47" name="Kmf47" value="698.6022"/>    <parameter metaid="metaid_0000025" id="Kmr47" name="Kmr47" value="483.8622"/>    <parameter metaid="metaid_0000026" id="kf48" name="kf48" value="16.833"/>    <parameter metaid="metaid_0000027" id="Kmf48" name="Kmf48" value="715.5688"/>    <parameter metaid="metaid_0000028" id="Kmr48" name="Kmr48" value="324.9294"/>    <parameter metaid="metaid_0000029" id="PTEN" name="PTEN" value="693.5786"/>    <parameter metaid="metaid_0000030" id="kf49" name="kf49" value="44.3501"/>    <parameter metaid="metaid_0000031" id="kr49" name="kr49" value="552.6746"/>    <parameter metaid="metaid_0000032" id="Kmf49" name="Kmf49" value="343.2483"/>    <parameter metaid="metaid_0000033" id="Kmr49" name="Kmr49" value="753.1667"/>    <parameter metaid="metaid_0000034" id="Kmr49b" name="Kmr49b" value="381.2208"/>    <parameter metaid="metaid_0000035" id="kr49b" name="kr49b" value="640.8212"/>    <parameter metaid="metaid_0000036" id="kf51" name="kf51" value="3.6515"/>    <parameter metaid="metaid_0000037" id="kr51" name="kr51" value="0"/>    <parameter metaid="metaid_0000038" id="Vmaxr51" name="Vmaxr51" value="16.737"/>    <parameter metaid="metaid_0000039" id="Kmf51" name="Kmf51" value="599.7076"/>    <parameter metaid="metaid_0000040" id="Kmr51" name="Kmr51" value="346.4779"/>    <parameter metaid="metaid_0000041" id="Kmrb51" name="Kmrb51" value="988.4496"/>    <parameter metaid="metaid_0000042" id="kf52" name="kf52" value="0.7745"/>    <parameter metaid="metaid_0000043" id="Vmaxr52" name="Vmaxr52" value="199.2773"/>    <parameter metaid="metaid_0000044" id="Kmf52" name="Kmf52" value="545.4408"/>    <parameter metaid="metaid_0000045" id="Kmr52" name="Kmr52" value="675.2994"/>    <parameter metaid="metaid_0000046" id="kf53" name="kf53" value="0.6094"/>    <parameter metaid="metaid_0000047" id="Vmaxr53" name="Vmaxr53" value="59.2314"/>    <parameter metaid="metaid_0000048" id="Kmf53" name="Kmf53" value="812.254"/>    <parameter metaid="metaid_0000049" id="Kmr53" name="Kmr53" value="944.7692"/>    <parameter metaid="metaid_0000050" id="kf54" name="kf54" value="0.0538"/>    <parameter metaid="metaid_0000051" id="Vmaxr54" name="Vmaxr54" value="588.2671"/>    <parameter metaid="metaid_0000052" id="Kmf54" name="Kmf54" value="457.9645"/>    <parameter metaid="metaid_0000053" id="Kmr54" name="Kmr54" value="336.183"/>    <parameter metaid="metaid_0000054" id="kf55" name="kf55" value="0.2256"/>    <parameter metaid="metaid_0000055" id="Vmaxr55" name="Vmaxr55" value="646.9003"/>    <parameter metaid="metaid_0000056" id="Kmf55" name="Kmf55" value="460.9446"/>    <parameter metaid="metaid_0000057" id="Kmr55" name="Kmr55" value="643.9247"/>    <parameter metaid="metaid_0000058" id="kf38" name="kf38" value="279.9929"/>    <parameter metaid="metaid_0000059" id="kf39" name="kf39" value="385.7428"/>    <parameter metaid="metaid_0000060" id="kf50" name="kf50" value="389.1061"/>    <parameter metaid="metaid_0000061" id="a98" name="a98" value="0.0849"/>    <parameter metaid="metaid_0000062" id="b98" name="b98" value="0.1833"/>    <parameter metaid="metaid_0000063" id="koff46" name="koff46" value="0.5194"/>    <parameter metaid="metaid_0000064" id="EGF_off" name="EGF_off" value="0.0175"/>    <parameter metaid="metaid_0000065" id="HRGoff_3" name="HRGoff_3" value="0.0009"/>    <parameter metaid="metaid_0000066" id="HRGoff_4" name="HRGoff_4" value="0.0973"/>    <parameter metaid="metaid_0000067" id="koff4" name="koff4" value="0.1717"/>    <parameter metaid="metaid_0000068" id="koff5" name="koff5" value="4.3985"/>    <parameter metaid="metaid_0000069" id="koff6" name="koff6" value="2.6619"/>    <parameter metaid="metaid_0000070" id="koff7" name="koff7" value="8.0557"/>    <parameter metaid="metaid_0000071" id="koff8" name="koff8" value="9.1034"/>    <parameter metaid="metaid_0000072" id="koff9" name="koff9" value="5.5425"/>    <parameter metaid="metaid_0000073" id="koff57" name="koff57" value="0.4526"/>    <parameter metaid="metaid_0000074" id="koff16" name="koff16" value="0.5737"/>    <parameter metaid="metaid_0000075" id="koff17" name="koff17" value="4.6874"/>    <parameter metaid="metaid_0000076" id="koff18" name="koff18" value="2.2768"/>    <parameter metaid="metaid_0000077" id="koff19" name="koff19" value="2.3361"/>    <parameter metaid="metaid_0000078" id="koff20" name="koff20" value="0.6761"/>    <parameter metaid="metaid_0000079" id="koff21" name="koff21" value="4.7291"/>    <parameter metaid="metaid_0000080" id="koff22" name="koff22" value="3.6962"/>    <parameter metaid="metaid_0000081" id="koff23" name="koff23" value="2.3619"/>    <parameter metaid="metaid_0000082" id="koff24" name="koff24" value="4.4226"/>    <parameter metaid="metaid_0000083" id="koff25" name="koff25" value="2.225"/>    <parameter metaid="metaid_0000084" id="koff26" name="koff26" value="0.0103"/>    <parameter metaid="metaid_0000085" id="koff27" name="koff27" value="1.8922"/>    <parameter metaid="metaid_0000086" id="koff28" name="koff28" value="4.6432"/>    <parameter metaid="metaid_0000087" id="koff29" name="koff29" value="2.0148"/>    <parameter metaid="metaid_0000088" id="koff30" name="koff30" value="4.9936"/>    <parameter metaid="metaid_0000089" id="koff31" name="koff31" value="1.2204"/>    <parameter metaid="metaid_0000090" id="koff32" name="koff32" value="3.8752"/>    <parameter metaid="metaid_0000091" id="koff33" name="koff33" value="1.2817"/>    <parameter metaid="metaid_0000092" id="koff34" name="koff34" value="3.2036"/>    <parameter metaid="metaid_0000093" id="koff35" name="koff35" value="1.8696"/>    <parameter metaid="metaid_0000094" id="koff36" name="koff36" value="1.2567"/>    <parameter metaid="metaid_0000095" id="koff37" name="koff37" value="0.4059"/>    <parameter metaid="metaid_0000096" id="koff65" name="koff65" value="0.1185"/>    <parameter metaid="metaid_0000097" id="koff66" name="koff66" value="2.2988"/>    <parameter metaid="metaid_0000098" id="koff67" name="koff67" value="1.6142"/>    <parameter metaid="metaid_0000099" id="koff40" name="koff40" value="3.1051"/>    <parameter metaid="metaid_0000100" id="koff41" name="koff41" value="7.0487"/>    <parameter metaid="metaid_0000101" id="koff42" name="koff42" value="3.5195"/>    <parameter metaid="metaid_0000102" id="koff43" name="koff43" value="0.5441"/>    <parameter metaid="metaid_0000103" id="koff44" name="koff44" value="0.4265"/>    <parameter metaid="metaid_0000104" id="koff45" name="koff45" value="3.9967"/>    <parameter metaid="metaid_0000105" id="koff58" name="koff58" value="6.3059"/>    <parameter metaid="metaid_0000106" id="koff59" name="koff59" value="9.172"/>    <parameter metaid="metaid_0000107" id="koff68" name="koff68" value="2.8871"/>    <parameter metaid="metaid_0000108" id="PTP1B_Abund" name="PTP1B_Abund" value="500"/>    <parameter metaid="metaid_0000109" id="kPTP10" name="kPTP10" value="29.8531"/>    <parameter metaid="metaid_0000110" id="kPTP11" name="kPTP11" value="78.204"/>    <parameter metaid="metaid_0000111" id="kPTP12" name="kPTP12" value="11.4211"/>    <parameter metaid="metaid_0000112" id="kPTP13" name="kPTP13" value="55.2104"/>    <parameter metaid="metaid_0000113" id="kPTP14" name="kPTP14" value="57.7506"/>    <parameter metaid="metaid_0000114" id="kPTP15" name="kPTP15" value="60.2628"/>    <parameter metaid="metaid_0000115" id="kPTP63" name="kPTP63" value="7.4766"/>    <parameter metaid="metaid_0000116" id="kPTP64" name="kPTP64" value="48.6335"/>    <parameter metaid="metaid_0000117" id="koff73" name="koff73" value="3.0048"/>    <parameter metaid="metaid_0000118" id="koff74" name="koff74" value="1.2496"/>    <parameter metaid="metaid_0000119" id="koff75" name="koff75" value="1.4323"/>    <parameter metaid="metaid_0000120" id="koff76" name="koff76" value="2.1542"/>    <parameter metaid="metaid_0000121" id="koff77" name="koff77" value="1.2237"/>    <parameter metaid="metaid_0000122" id="koff78" name="koff78" value="0.2007"/>    <parameter metaid="metaid_0000123" id="koff79" name="koff79" value="1.1852"/>    <parameter metaid="metaid_0000124" id="koff80" name="koff80" value="2.9373"/>    <parameter metaid="metaid_0000125" id="kPTP38" name="kPTP38" value="83.4465"/>    <parameter metaid="metaid_0000126" id="kPTP39" name="kPTP39" value="79.6132"/>    <parameter metaid="metaid_0000127" id="koff88" name="koff88" value="3.9255"/>    <parameter metaid="metaid_0000128" id="kPTP50" name="kPTP50" value="96.5716"/>    <parameter metaid="metaid_0000129" id="kf81" name="kf81" value="1.361"/>    <parameter metaid="metaid_0000130" id="Vmaxr81" name="Vmaxr81" value="242.6034"/>    <parameter metaid="metaid_0000131" id="Kmf81" name="Kmf81" value="485.2626"/>    <parameter metaid="metaid_0000132" id="Kmr81" name="Kmr81" value="323.4012"/>    <parameter metaid="metaid_0000133" id="kf82" name="kf82" value="6.9987"/>    <parameter metaid="metaid_0000134" id="Vmaxr82" name="Vmaxr82" value="398.1931"/>    <parameter metaid="metaid_0000135" id="Kmf82" name="Kmf82" value="781.4374"/>    <parameter metaid="metaid_0000136" id="Kmr82" name="Kmr82" value="595.8395"/>    <parameter metaid="metaid_0000137" id="kf83" name="kf83" value="1.7628"/>    <parameter metaid="metaid_0000138" id="Vmaxr83" name="Vmaxr83" value="534.0531"/>    <parameter metaid="metaid_0000139" id="Kmf83" name="Kmf83" value="609.4766"/>    <parameter metaid="metaid_0000140" id="Kmr83" name="Kmr83" value="653.5184"/>    <parameter metaid="metaid_0000141" id="kf84" name="kf84" value="4.6894"/>    <parameter metaid="metaid_0000142" id="Vmaxr84" name="Vmaxr84" value="634.1626"/>    <parameter metaid="metaid_0000143" id="Kmf84" name="Kmf84" value="622.3847"/>    <parameter metaid="metaid_0000144" id="Kmr84" name="Kmr84" value="258.4637"/>    <parameter metaid="metaid_0000145" id="kf85" name="kf85" value="6.7591"/>    <parameter metaid="metaid_0000146" id="Vmaxr85" name="Vmaxr85" value="369.2261"/>    <parameter metaid="metaid_0000147" id="Kmf85" name="Kmf85" value="179.6486"/>    <parameter metaid="metaid_0000148" id="Kmr85" name="Kmr85" value="290.7667"/>    <parameter metaid="metaid_0000149" id="kcon49" name="kcon49" value="9.9783"/>    <parameter metaid="metaid_0000150" id="kon1" name="kon1" value="0.00010086"/>    <parameter metaid="metaid_0000151" id="kon86" name="kon86" value="0.0038"/>    <parameter metaid="metaid_0000152" id="kon2" name="kon2" value="0.0059"/>    <parameter metaid="metaid_0000153" id="kon3" name="kon3" value="0.0334"/>    <parameter metaid="metaid_0000154" id="kon87" name="kon87" value="0.0008"/>    <parameter metaid="metaid_0000155" id="kon4" name="kon4" value="0.5005"/>    <parameter metaid="metaid_0000156" id="kon5" name="kon5" value="2.5427"/>    <parameter metaid="metaid_0000157" id="kon6" name="kon6" value="0.2283"/>    <parameter metaid="metaid_0000158" id="kon7" name="kon7" value="1.0606"/>    <parameter metaid="metaid_0000159" id="kon8" name="kon8" value="1.0259"/>    <parameter metaid="metaid_0000160" id="kon9" name="kon9" value="2.2868"/>    <parameter metaid="metaid_0000161" id="kon57" name="kon57" value="0.0039"/>    <parameter metaid="metaid_0000162" id="kf10" name="kf10" value="0.6496"/>    <parameter metaid="metaid_0000163" id="kf11" name="kf11" value="0.3721"/>    <parameter metaid="metaid_0000164" id="kf12" name="kf12" value="1.8012"/>    <parameter metaid="metaid_0000165" id="kf13" name="kf13" value="0.8875"/>    <parameter metaid="metaid_0000166" id="kf14" name="kf14" value="6.1726"/>    <parameter metaid="metaid_0000167" id="kf15" name="kf15" value="1.3565"/>    <parameter metaid="metaid_0000168" id="kf63" name="kf63" value="0.9297"/>    <parameter metaid="metaid_0000169" id="kf64" name="kf64" value="1.2083"/>    <parameter metaid="metaid_0000170" id="kon16" name="kon16" value="0.0097"/>    <parameter metaid="metaid_0000171" id="kon17" name="kon17" value="0.0049"/>    <parameter metaid="metaid_0000172" id="kon18" name="kon18" value="0.0117"/>    <parameter metaid="metaid_0000173" id="kon73" name="kon73" value="0.0116"/>    <parameter metaid="metaid_0000174" id="kon19" name="kon19" value="0.0896"/>    <parameter metaid="metaid_0000175" id="kon20" name="kon20" value="0.0478"/>    <parameter metaid="metaid_0000176" id="kon21" name="kon21" value="0.0114"/>    <parameter metaid="metaid_0000177" id="kon74" name="kon74" value="0.0133"/>    <parameter metaid="metaid_0000178" id="kon22" name="kon22" value="0.0007"/>    <parameter metaid="metaid_0000179" id="kon23" name="kon23" value="0.0138"/>    <parameter metaid="metaid_0000180" id="kon24" name="kon24" value="0.005"/>    <parameter metaid="metaid_0000181" id="kon25" name="kon25" value="0.0995"/>    <parameter metaid="metaid_0000182" id="kon75" name="kon75" value="0.0137"/>    <parameter metaid="metaid_0000183" id="kon26" name="kon26" value="0.0355"/>    <parameter metaid="metaid_0000184" id="kon27" name="kon27" value="0.0201"/>    <parameter metaid="metaid_0000185" id="kon28" name="kon28" value="0.0074"/>    <parameter metaid="metaid_0000186" id="kon29" name="kon29" value="0.0346"/>    <parameter metaid="metaid_0000187" id="kon76" name="kon76" value="0.0053"/>    <parameter metaid="metaid_0000188" id="kon30" name="kon30" value="0.002"/>    <parameter metaid="metaid_0000189" id="kon31" name="kon31" value="0.0032"/>    <parameter metaid="metaid_0000190" id="kon32" name="kon32" value="0.0009"/>    <parameter metaid="metaid_0000191" id="kon33" name="kon33" value="0.0335"/>    <parameter metaid="metaid_0000192" id="kon77" name="kon77" value="0.0101"/>    <parameter metaid="metaid_0000193" id="kon34" name="kon34" value="0.0001"/>    <parameter metaid="metaid_0000194" id="kon35" name="kon35" value="0.0602"/>    <parameter metaid="metaid_0000195" id="kon36" name="kon36" value="0.0043"/>    <parameter metaid="metaid_0000196" id="kon37" name="kon37" value="0.0791"/>    <parameter metaid="metaid_0000197" id="kon78" name="kon78" value="0.0076"/>    <parameter metaid="metaid_0000198" id="kon79" name="kon79" value="0.0078"/>    <parameter metaid="metaid_0000199" id="kon65" name="kon65" value="0.0123"/>    <parameter metaid="metaid_0000200" id="kon66" name="kon66" value="0.00019264"/>    <parameter metaid="metaid_0000201" id="kon67" name="kon67" value="6.6667e-05"/>    <parameter metaid="metaid_0000202" id="kon80" name="kon80" value="0.0002"/>    <parameter metaid="metaid_0000203" id="kon40" name="kon40" value="0.0191"/>    <parameter metaid="metaid_0000204" id="kon41" name="kon41" value="0.0051"/>    <parameter metaid="metaid_0000205" id="kon42" name="kon42" value="0.0023"/>    <parameter metaid="metaid_0000206" id="kon43" name="kon43" value="0.0127"/>    <parameter metaid="metaid_0000207" id="kon44" name="kon44" value="0.0122"/>    <parameter metaid="metaid_0000208" id="kon45" name="kon45" value="0.0028"/>    <parameter metaid="metaid_0000209" id="kon88" name="kon88" value="0.0108"/>    <parameter metaid="metaid_0000210" id="kon46" name="kon46" value="0.0148"/>    <parameter metaid="metaid_0000211" id="kon58" name="kon58" value="0.0215"/>    <parameter metaid="metaid_0000212" id="kon59" name="kon59" value="0.0077"/>    <parameter metaid="metaid_0000213" id="kon60" name="kon60" value="0.00011994"/>    <parameter metaid="metaid_0000214" id="VeVc" name="VeVc" value="33.3"/>    <parameter metaid="metaid_0000215" id="koff60" name="koff60" value="4.9981"/>    <parameter metaid="metaid_0000216" id="koff61" name="koff61" value="5.229"/>    <parameter metaid="metaid_0000217" id="kon61" name="kon61" value="0.8048"/>    <parameter metaid="metaid_0000218" id="kon62" name="kon62" value="1.782"/>    <parameter metaid="metaid_0000219" id="koff62" name="koff62" value="5.5142"/>    <parameter metaid="metaid_0000220" id="kon68" name="kon68" value="0.0045"/>    <parameter metaid="metaid_0000221" id="kon69" name="kon69" value="0.0084"/>    <parameter metaid="metaid_0000222" id="koff69" name="koff69" value="3.97"/>    <parameter metaid="metaid_0000223" id="kon70" name="kon70" value="0.0116"/>    <parameter metaid="metaid_0000224" id="koff70" name="koff70" value="2.6069"/>    <parameter metaid="metaid_0000225" id="kon71" name="kon71" value="0.0078"/>    <parameter metaid="metaid_0000226" id="koff71" name="koff71" value="2.2988"/>    <parameter metaid="metaid_0000227" id="kon72" name="kon72" value="0.0355"/>    <parameter metaid="metaid_0000228" id="koff72" name="koff72" value="0.907"/>    <parameter metaid="metaid_0000229" id="eps" name="eps" value="1e-16"/>    <parameter metaid="metaid_0000230" id="kon89" name="kon89" value="0.1997"/>    <parameter metaid="metaid_0000231" id="koff89" name="koff89" value="99.9637"/>    <parameter metaid="metaid_0000232" id="kcat90" name="kcat90" value="20.0037"/>    <parameter metaid="metaid_0000233" id="kon91" name="kon91" value="0.1966"/>    <parameter metaid="metaid_0000234" id="koff91" name="koff91" value="99.9983"/>    <parameter metaid="metaid_0000235" id="kcat92" name="kcat92" value="0.2004"/>    <parameter metaid="metaid_0000236" id="kon93" name="kon93" value="0.2003"/>    <parameter metaid="metaid_0000237" id="koff93" name="koff93" value="100.0037"/>    <parameter metaid="metaid_0000238" id="kcat94" name="kcat94" value="0.9966"/>    <parameter metaid="metaid_0000239" id="kon95" name="kon95" value="0.1993"/>    <parameter metaid="metaid_0000240" id="koff95" name="koff95" value="100.0023"/>    <parameter metaid="metaid_0000241" id="kcat96" name="kcat96" value="19.9851"/>    <parameter metaid="metaid_0000242" id="ERKPpase_Abund" name="ERKPpase_Abund" value="35.005"/>  </listOfParameters>  <listOfRules>    <assignmentRule metaid="metaid_0000466" variable="norm_Akt_star">      <math xmlns="http://www.w3.org/1998/Math/MathML">        <apply>          <divide/>          <ci> Aktstar </ci>          <cn> 18.8 </cn>        </apply>      </math>    </assignmentRule>    <assignmentRule metaid="metaid_0000467" variable="norm_Erk_star">      <math xmlns="http://www.w3.org/1998/Math/MathML">        <apply>          <divide/>          <apply>            <plus/>            <ci> ERKstar </ci>            <ci> ERKstar_ERKpase </ci>          </apply>          <cn> 589.5 </cn>        </apply>      </math>    </assignmentRule>  </listOfRules>  <listOfReactions>    <reaction metaid="metaid_0000362" id="EGF_Binding_to_ErbB1" name="EGF Binding to ErbB1" fast="false">      <listOfReactants>        <speciesReference species="E1"/>      </listOfReactants>      <listOfProducts>        <speciesReference species="E_E1"/>      </listOfProducts>      <listOfModifiers>        <modifierSpeciesReference species="E"/>      </listOfModifiers>      <kineticLaw>        <math xmlns="http://www.w3.org/1998/Math/MathML">          <apply>            <times/>            <ci> membrane </ci>            <apply>              <minus/>              <apply>                <times/>                <ci> kon1 </ci>                <ci> E </ci>                <ci> E1 </ci>              </apply>              <apply>                <times/>                <ci> EGF_off </ci>                <ci> E_E1 </ci>              </apply>            </apply>          </apply>        </math>      </kineticLaw>    </reaction>    <reaction metaid="metaid_0000363" id="HRG_Binding_to_ErbB3" name="HRG Binding to ErbB3" fast="false">      <listOfReactants>        <speciesReference species="E3"/>      </listOfReactants>      <listOfProducts>        <speciesReference species="H_E3"/>      </listOfProducts>      <listOfModifiers>        <modifierSpeciesReference species="H"/>      </listOfModifiers>      <kineticLaw>        <math xmlns="http://www.w3.org/1998/Math/MathML">          <apply>            <times/>            <ci> membrane </ci>            <apply>              <minus/>              <apply>                <times/>                <ci> kon2 </ci>                <ci> H </ci>                <ci> E3 </ci>              </apply>              <apply>                <times/>                <ci> HRGoff_3 </ci>                <ci> H_E3 </ci>              </apply>            </apply>          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