{"text_format":"3","workbook":"xls","n_sheets":1,"sheets":["Additional file 3"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Additional file 3","index":0,"n_rows":57,"n_cols":16,"rows_kept":57,"merged":[[0,0,0,15],[56,0,56,14]],"flags":["formulas_cached_only"]}
["Additional file 3 Estimates of codon usage bias for ribosomal proteins in E. coli"]
["ID","Locus","Product Name","Length (bp)","CDC","P-value*","Scaled Nc","Scaled Nc'","GC","AG","GC1","AG1","GC2","AG2","GC3","AG3"]
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["b3065","rpsU","30S ribosomal subunit protein S21",213,{"v":0.434428,"d":"0.434"},{"v":0,"d":"0.0000"},{"v":0.376156,"d":"0.376"},{"v":0.418595,"d":"0.419"},{"v":0.525822,"d":"0.526"},{"v":0.535211,"d":"0.535"},{"v":0.661972,"d":"0.662"},{"v":0.577465,"d":"0.577"},{"v":0.464789,"d":"0.465"},{"v":0.549296,"d":"0.549"},{"v":0.450704,"d":"0.451"},{"v":0.478873,"d":"0.479"}]
["b3703","rpmH","50S ribosomal subunit protein L34",138,{"v":0.425221,"d":"0.425"},{"v":0.004,"d":"0.0040"},{"v":0.309205,"d":"0.309"},{"v":0.277124,"d":"0.277"},{"v":0.528986,"d":"0.529"},{"v":0.449275,"d":"0.449"},{"v":0.630435,"d":"0.630"},{"v":0.5,"d":"0.500"},{"v":0.565217,"d":"0.565"},{"v":0.521739,"d":"0.522"},{"v":0.391304,"d":"0.391"},{"v":0.326087,"d":"0.326"}]
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["b4200","rpsF","30S ribosomal subunit protein S6",393,{"v":0.286523,"d":"0.287"},{"v":0,"d":"0.0000"},{"v":0.547146,"d":"0.547"},{"v":0.602576,"d":"0.603"},{"v":0.529262,"d":"0.529"},{"v":0.529262,"d":"0.529"},{"v":0.664122,"d":"0.664"},{"v":0.671756,"d":"0.672"},{"v":0.366412,"d":"0.366"},{"v":0.534351,"d":"0.534"},{"v":0.557252,"d":"0.557"},{"v":0.381679,"d":"0.382"}]
["b3316","rpsS","30S ribosomal subunit protein S19",276,{"v":0.285778,"d":"0.286"},0.0104,{"v":0.304963,"d":"0.305"},{"v":0.345593,"d":"0.346"},{"v":0.492754,"d":"0.493"},{"v":0.521739,"d":"0.522"},{"v":0.565217,"d":"0.565"},{"v":0.619565,"d":"0.620"},{"v":0.402174,"d":"0.402"},{"v":0.5,"d":"0.500"},{"v":0.51087,"d":"0.511"},{"v":0.445652,"d":"0.446"}]
["b3315","rplV","50S ribosomal subunit protein L22",330,{"v":0.284739,"d":"0.285"},{"v":0,"d":"0.0000"},{"v":0.409456,"d":"0.409"},{"v":0.434849,"d":"0.435"},{"v":0.5,"d":"0.500"},{"v":0.515152,"d":"0.515"},{"v":0.6,"d":"0.600"},{"v":0.7,"d":"0.700"},{"v":0.381818,"d":"0.382"},{"v":0.472727,"d":"0.473"},{"v":0.518182,"d":"0.518"},{"v":0.372727,"d":"0.373"}]
["b3296","rpsD","30S ribosomal subunit protein S4",618,{"v":0.284332,"d":"0.284"},{"v":0,"d":"0.0000"},{"v":0.474398,"d":"0.474"},{"v":0.502407,"d":"0.502"},{"v":0.509709,"d":"0.510"},{"v":0.537217,"d":"0.537"},{"v":0.631068,"d":"0.631"},{"v":0.606796,"d":"0.607"},{"v":0.38835,"d":"0.388"},{"v":0.563107,"d":"0.563"},{"v":0.509709,"d":"0.510"},{"v":0.441748,"d":"0.442"}]
["b3298","rpsM","30S ribosomal subunit protein S13",354,{"v":0.280228,"d":"0.280"},{"v":0,"d":"0.0000"},{"v":0.378076,"d":"0.378"},{"v":0.401449,"d":"0.401"},{"v":0.522599,"d":"0.523"},{"v":0.514124,"d":"0.514"},{"v":0.618644,"d":"0.619"},{"v":0.661017,"d":"0.661"},{"v":0.457627,"d":"0.458"},{"v":0.525424,"d":"0.525"},{"v":0.491525,"d":"0.492"},{"v":0.355932,"d":"0.356"}]
["b3320","rplC","50S ribosomal subunit protein L3",627,{"v":0.278136,"d":"0.278"},{"v":0,"d":"0.0000"},{"v":0.660876,"d":"0.661"},{"v":0.681334,"d":"0.681"},{"v":0.516746,"d":"0.517"},{"v":0.535885,"d":"0.536"},{"v":0.631579,"d":"0.632"},{"v":0.732057,"d":"0.732"},{"v":0.430622,"d":"0.431"},{"v":0.497608,"d":"0.498"},{"v":0.488038,"d":"0.488"},{"v":0.37799,"d":"0.378"}]
["b3303","rpsE","30S ribosomal subunit protein S5",501,{"v":0.268686,"d":"0.269"},{"v":0,"d":"0.0000"},{"v":0.608159,"d":"0.608"},{"v":0.638359,"d":"0.638"},{"v":0.50499,"d":"0.505"},{"v":0.526946,"d":"0.527"},{"v":0.634731,"d":"0.635"},{"v":0.724551,"d":"0.725"},{"v":0.42515,"d":"0.425"},{"v":0.467066,"d":"0.467"},{"v":0.45509,"d":"0.455"},{"v":0.389222,"d":"0.389"}]
["b3341","rpsG","30S ribosomal subunit protein S7",537,{"v":0.268305,"d":"0.268"},{"v":0,"d":"0.0000"},{"v":0.481422,"d":"0.481"},{"v":0.486388,"d":"0.486"},{"v":0.502793,"d":"0.503"},{"v":0.506518,"d":"0.507"},{"v":0.636872,"d":"0.637"},{"v":0.597765,"d":"0.598"},{"v":0.446927,"d":"0.447"},{"v":0.486034,"d":"0.486"},{"v":0.424581,"d":"0.425"},{"v":0.435754,"d":"0.436"}]
["b3936","rpmE","50S ribosomal subunit protein L31",210,{"v":0.266914,"d":"0.267"},0.1136,{"v":0.260761,"d":"0.261"},{"v":0.22692,"d":"0.227"},{"v":0.5,"d":"0.500"},{"v":0.504762,"d":"0.505"},{"v":0.485714,"d":"0.486"},{"v":0.642857,"d":"0.643"},{"v":0.414286,"d":"0.414"},{"v":0.6,"d":"0.600"},{"v":0.6,"d":"0.600"},{"v":0.271429,"d":"0.271"}]
["b3297","rpsK","30S ribosomal subunit protein S11",387,{"v":0.266227,"d":"0.266"},{"v":0,"d":"0.0000"},{"v":0.613078,"d":"0.613"},{"v":0.614759,"d":"0.615"},{"v":0.51938,"d":"0.519"},{"v":0.496124,"d":"0.496"},{"v":0.596899,"d":"0.597"},{"v":0.658915,"d":"0.659"},{"v":0.542636,"d":"0.543"},{"v":0.472868,"d":"0.473"},{"v":0.418605,"d":"0.419"},{"v":0.356589,"d":"0.357"}]
["b3306","rpsH","30S ribosomal subunit protein S8",390,{"v":0.265022,"d":"0.265"},{"v":0,"d":"0.0000"},{"v":0.568541,"d":"0.569"},{"v":0.599041,"d":"0.599"},{"v":0.505128,"d":"0.505"},{"v":0.530769,"d":"0.531"},{"v":0.615385,"d":"0.615"},{"v":0.7,"d":"0.700"},{"v":0.4,"d":"0.400"},{"v":0.469231,"d":"0.469"},{"v":0.5,"d":"0.500"},{"v":0.423077,"d":"0.423"}]
["b3308","rplE","50S ribosomal subunit protein L5",537,{"v":0.264001,"d":"0.264"},{"v":0,"d":"0.0000"},{"v":0.51681,"d":"0.517"},{"v":0.51662,"d":"0.517"},{"v":0.500931,"d":"0.501"},{"v":0.504655,"d":"0.505"},{"v":0.575419,"d":"0.575"},{"v":0.648045,"d":"0.648"},{"v":0.379888,"d":"0.380"},{"v":0.486034,"d":"0.486"},{"v":0.547486,"d":"0.547"},{"v":0.379888,"d":"0.380"}]
["b3309","rplX","50S ribosomal subunit protein L24",312,{"v":0.25882,"d":"0.259"},0.0024,{"v":0.490698,"d":"0.491"},{"v":0.572639,"d":"0.573"},{"v":0.464744,"d":"0.465"},{"v":0.560897,"d":"0.561"},{"v":0.557692,"d":"0.558"},{"v":0.759615,"d":"0.760"},{"v":0.346154,"d":"0.346"},{"v":0.519231,"d":"0.519"},{"v":0.490385,"d":"0.490"},{"v":0.403846,"d":"0.404"}]
["b3305","rplF","50S ribosomal subunit protein L6",531,{"v":0.249631,"d":"0.250"},{"v":0,"d":"0.0000"},{"v":0.624602,"d":"0.625"},{"v":0.620373,"d":"0.620"},{"v":0.52354,"d":"0.524"},{"v":0.517891,"d":"0.518"},{"v":0.666667,"d":"0.667"},{"v":0.694915,"d":"0.695"},{"v":0.423729,"d":"0.424"},{"v":0.485876,"d":"0.486"},{"v":0.480226,"d":"0.480"},{"v":0.372881,"d":"0.373"}]
["b3310","rplN","50S ribosomal subunit protein L14",369,{"v":0.243523,"d":"0.244"},0.0006,{"v":0.353215,"d":"0.353"},{"v":0.373617,"d":"0.374"},{"v":0.514905,"d":"0.515"},{"v":0.525745,"d":"0.526"},{"v":0.593496,"d":"0.593"},{"v":0.682927,"d":"0.683"},{"v":0.398374,"d":"0.398"},{"v":0.495935,"d":"0.496"},{"v":0.552846,"d":"0.553"},{"v":0.398374,"d":"0.398"}]
["Note: The calculation of P-value is based on 10,000 bootstrap replicates."]