{"text_format":"3","workbook":"xls","n_sheets":2,"sheets":["Sheet1","Sheet2"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Sheet1","index":0,"n_rows":27,"n_cols":10,"rows_kept":27,"flags":["formulas_cached_only"]}
["Standard deviations (%) of AUC values shown in Table 1"]
["DE method","edgeR","edgeR","edgeR","DESeq","DESeq","DESeq","baySeq","baySeq","baySeq"]
["PG1",{"v":0.5,"d":"50%"},{"v":0.7,"d":"70%"},{"v":0.9,"d":"90%"},{"v":0.5,"d":"50%"},{"v":0.7,"d":"70%"},{"v":0.9,"d":"90%"},{"v":0.5,"d":"50%"},{"v":0.7,"d":"70%"},{"v":0.9,"d":"90%"}]
["(a) TMM"]
["PDEG = 5%",{"v":0.00940940762121266,"d":"0.00941"},{"v":0.0101177935062669,"d":"0.01012"},{"v":0.00923232440319552,"d":"0.00923"},{"v":0.00995745994259177,"d":"0.00996"},{"v":0.0105424595234446,"d":"0.01054"},{"v":0.0097559053857333,"d":"0.00976"},{"v":0.00873346076484454,"d":"0.00873"},{"v":0.00895796407192019,"d":"0.00896"},{"v":0.00887539928496381,"d":"0.00888"}]
["PDEG = 15%",{"v":0.00468970767950375,"d":"0.00469"},{"v":0.0060208677921272,"d":"0.00602"},{"v":0.00553385297808424,"d":"0.00553"},{"v":0.00520012689947761,"d":"0.00520"},{"v":0.00628194927507902,"d":"0.00628"},{"v":0.00588358870643568,"d":"0.00588"},{"v":0.00453453355836395,"d":"0.00453"},{"v":0.00467581101438664,"d":"0.00468"},{"v":0.00472574636948872,"d":"0.00473"}]
["PDEG = 25%",{"v":0.00446572044554474,"d":"0.00447"},{"v":0.00420313547976841,"d":"0.00420"},{"v":0.00432761358551342,"d":"0.00433"},{"v":0.00473003770787641,"d":"0.00473"},{"v":0.00462121555081546,"d":"0.00462"},{"v":0.0045376975860128,"d":"0.00454"},{"v":0.00422694789969453,"d":"0.00423"},{"v":0.00389154048507933,"d":"0.00389"},{"v":0.0040549287529859,"d":"0.00405"}]
["(b) DEGES/TbT"]
["PDEG = 5%",{"v":0.00941382078948071,"d":"0.00941"},{"v":0.010110304909043,"d":"0.01011"},{"v":0.00921001204322783,"d":"0.00921"},{"v":0.00991365645112494,"d":"0.00991"},{"v":0.0105278208523897,"d":"0.01053"},{"v":0.00970751863661955,"d":"0.00971"},{"v":0.00872575383695281,"d":"0.00873"},{"v":0.00893674485190346,"d":"0.00894"},{"v":0.00882213441635133,"d":"0.00882"}]
["PDEG = 15%",{"v":0.0046999188731833,"d":"0.00470"},{"v":0.00597683970811994,"d":"0.00598"},{"v":0.00550897423789753,"d":"0.00551"},{"v":0.0052007926028085,"d":"0.00520"},{"v":0.00626655223386501,"d":"0.00627"},{"v":0.00582192991415351,"d":"0.00582"},{"v":0.00454237253832476,"d":"0.00454"},{"v":0.00462356611377827,"d":"0.00462"},{"v":0.00468595839672839,"d":"0.00469"}]
["PDEG = 25%",{"v":0.00447015872845789,"d":"0.00447"},{"v":0.00418061240619314,"d":"0.00418"},{"v":0.00410938783632158,"d":"0.00411"},{"v":0.00470215692512341,"d":"0.00470"},{"v":0.00461605701244902,"d":"0.00462"},{"v":0.00435132559400442,"d":"0.00435"},{"v":0.00422489069446113,"d":"0.00422"},{"v":0.00383426408240433,"d":"0.00383"},{"v":0.00383939611140702,"d":"0.00384"}]
["(c) DEGES/edgeR"]
["PDEG = 5%",{"v":0.00941843606784595,"d":"0.00942"},{"v":0.0100790547031089,"d":"0.01008"},{"v":0.00925058275529737,"d":"0.00925"},{"v":0.00990751477619608,"d":"0.00991"},{"v":0.0104736676012363,"d":"0.01047"},{"v":0.00973179514965981,"d":"0.00973"},{"v":0.00872789534286361,"d":"0.00873"},{"v":0.0089174188636408,"d":"0.00892"},{"v":0.0088475976572202,"d":"0.00885"}]
["PDEG = 15%",{"v":0.00468558384833082,"d":"0.00469"},{"v":0.0059670779894393,"d":"0.00597"},{"v":0.00549868372484809,"d":"0.00550"},{"v":0.00521833907264017,"d":"0.00522"},{"v":0.00622249805798977,"d":"0.00622"},{"v":0.00582301360954774,"d":"0.00582"},{"v":0.004528875642401,"d":"0.00453"},{"v":0.00457489426979723,"d":"0.00457"},{"v":0.00467462846683288,"d":"0.00467"}]
["PDEG = 25%",{"v":0.00446298670999385,"d":"0.00446"},{"v":0.00416232233708759,"d":"0.00416"},{"v":0.0041243695032592,"d":"0.00412"},{"v":0.00471909044315084,"d":"0.00472"},{"v":0.00460381135758529,"d":"0.00460"},{"v":0.00434783163170144,"d":"0.00435"},{"v":0.00421910754547666,"d":"0.00422"},{"v":0.00384139820987056,"d":"0.00384"},{"v":0.00381104897972715,"d":"0.00381"}]
["(d) iDEGES/edgeR"]
["PDEG = 5%",{"v":0.00939121244005063,"d":"0.00939"},{"v":0.0101172856640478,"d":"0.01012"},{"v":0.00925866842824406,"d":"0.00926"},{"v":0.00991158166793386,"d":"0.00991"},{"v":0.0105017780826736,"d":"0.01050"},{"v":0.00971921185901623,"d":"0.00972"},{"v":0.00873021259118961,"d":"0.00873"},{"v":0.00892882843333644,"d":"0.00893"},{"v":0.00885819102685196,"d":"0.00886"}]
["PDEG = 15%",{"v":0.00471081640142251,"d":"0.00471"},{"v":0.0059807114772127,"d":"0.00598"},{"v":0.00551326797874068,"d":"0.00551"},{"v":0.00522361922563044,"d":"0.00522"},{"v":0.00623670784263811,"d":"0.00624"},{"v":0.00584778938731679,"d":"0.00585"},{"v":0.00452880056963883,"d":"0.00453"},{"v":0.004596235635002,"d":"0.00460"},{"v":0.00468605002437031,"d":"0.00469"}]
["PDEG = 25%",{"v":0.00447283733317637,"d":"0.00447"},{"v":0.00416405445753145,"d":"0.00416"},{"v":0.0040011591164772,"d":"0.00400"},{"v":0.0047197092313654,"d":"0.00472"},{"v":0.0045955840901193,"d":"0.00460"},{"v":0.00421992816532587,"d":"0.00422"},{"v":0.00422050796223287,"d":"0.00422"},{"v":0.00383796259994052,"d":"0.00384"},{"v":0.0036760245588302,"d":"0.00368"}]
["(e) iDEGES/TDT"]
["PDEG = 5%",{"v":0.00939183155650685,"d":"0.00939"},{"v":0.0101116176107124,"d":"0.01011"},{"v":0.00924139774716324,"d":"0.00924"},{"v":0.00991565546477209,"d":"0.00992"},{"v":0.0105078229130257,"d":"0.01051"},{"v":0.00972310797023806,"d":"0.00972"},{"v":0.0087269685643161,"d":"0.00873"},{"v":0.0089475124579504,"d":"0.00895"},{"v":0.00884857766772653,"d":"0.00885"}]
["PDEG = 15%",{"v":0.00468582111503043,"d":"0.00469"},{"v":0.00596338954972447,"d":"0.00596"},{"v":0.00544879178226734,"d":"0.00545"},{"v":0.00519045019444171,"d":"0.00519"},{"v":0.00618433072396972,"d":"0.00618"},{"v":0.00575209093842298,"d":"0.00575"},{"v":0.00452901000777977,"d":"0.00453"},{"v":0.00456465353230114,"d":"0.00456"},{"v":0.00467709542770007,"d":"0.00468"}]
["PDEG = 25%",{"v":0.00447409410343953,"d":"0.00447"},{"v":0.00417707569947054,"d":"0.00418"},{"v":0.00417292383920794,"d":"0.00417"},{"v":0.0047103728397393,"d":"0.00471"},{"v":0.00459564116637557,"d":"0.00460"},{"v":0.00439157124621498,"d":"0.00439"},{"v":0.0042346644548751,"d":"0.00423"},{"v":0.00383129638636184,"d":"0.00383"},{"v":0.00388661251287647,"d":"0.00389"}]
["(f) iDEGES/DESeq"]
["PDEG = 5%",{"v":0.00938827202183081,"d":"0.00939"},{"v":0.0101056129534497,"d":"0.01011"},{"v":0.00921472145101993,"d":"0.00921"},{"v":0.00997658583393821,"d":"0.00998"},{"v":0.0104817647719522,"d":"0.01048"},{"v":0.0097032964622913,"d":"0.00970"},{"v":0.00872393160245571,"d":"0.00872"},{"v":0.00890510062645202,"d":"0.00891"},{"v":0.00880766920669781,"d":"0.00881"}]
["PDEG = 15%",{"v":0.00468508782697611,"d":"0.00469"},{"v":0.00599112811037269,"d":"0.00599"},{"v":0.00547405448104963,"d":"0.00547"},{"v":0.0052021226995717,"d":"0.00520"},{"v":0.00623941818973746,"d":"0.00624"},{"v":0.00576189378175574,"d":"0.00576"},{"v":0.00452377413945197,"d":"0.00452"},{"v":0.00457404714970626,"d":"0.00457"},{"v":0.00464395698425369,"d":"0.00464"}]
["PDEG = 25%",{"v":0.00446524329557052,"d":"0.00447"},{"v":0.00415043818224429,"d":"0.00415"},{"v":0.0040980095883116,"d":"0.00410"},{"v":0.00471159211466017,"d":"0.00471"},{"v":0.00457662694986082,"d":"0.00458"},{"v":0.00432648296414002,"d":"0.00433"},{"v":0.0042302462699004,"d":"0.00423"},{"v":0.00382402956846157,"d":"0.00382"},{"v":0.00391277625235012,"d":"0.00391"}]

{"sheet":"Sheet2","index":1,"n_rows":27,"n_cols":7,"rows_kept":27,"merged":[[1,1,1,3],[1,4,1,6]],"flags":["formulas_cached_only"]}
[]
[null,"Estimated PDEG (%)",null,null,"Accuracy (%)"]
["PG1",{"v":0.5,"d":"50%"},{"v":0.7,"d":"70%"},{"v":0.9,"d":"90%"},{"v":0.5,"d":"50%"},{"v":0.7,"d":"70%"},{"v":0.9,"d":"90%"}]
["(a) TMM"]
["PDEG = 5%","-","-","-","-","-","-"]
["PDEG = 15%","-","-","-","-","-","-"]
["PDEG = 25%","-","-","-","-","-","-"]
["(b) DEGES/TbT"]
["PDEG = 5%",{"v":5.427068,"d":"5.427"},{"v":5.424958,"d":"5.425"},{"v":5.388769,"d":"5.389"},{"v":95.5898,"d":"95.590"},{"v":95.5797,"d":"95.580"},{"v":95.5816,"d":"95.582"}]
["PDEG = 15%",{"v":12.802831000000001,"d":"12.803"},{"v":12.716171000000001,"d":"12.716"},{"v":12.58522,"d":"12.585"},91.355,{"v":91.2693,"d":"91.269"},{"v":90.95,"d":"90.950"}]
["PDEG = 25%",{"v":20.38445,"d":"20.384"},{"v":20.275964,"d":"20.276"},{"v":19.972443000000002,"d":"19.972"},{"v":87.8868,"d":"87.887"},{"v":87.58160000000001,"d":"87.582"},{"v":86.56099999999999,"d":"86.561"}]
["(c) DEGES/edgeR"]
["PDEG = 5%",{"v":3.7289000000000003,"d":"3.729"},{"v":3.7034,"d":"3.703"},{"v":3.6805999999999996,"d":"3.681"},96.358,{"v":96.3528,"d":"96.353"},{"v":96.32220000000001,"d":"96.322"}]
["PDEG = 15%",{"v":10.4284,"d":"10.428"},10.323,{"v":10.0996,"d":"10.100"},{"v":92.8064,"d":"92.806"},92.726,{"v":92.4164,"d":"92.416"}]
["PDEG = 25%",17.183,{"v":16.9742,"d":"16.974"},{"v":16.3203,"d":"16.320"},{"v":89.27340000000001,"d":"89.273"},{"v":88.97,"d":"88.970"},{"v":88.10090000000001,"d":"88.101"}]
["(d) iDEGES/edgeR"]
["PDEG = 5%",{"v":3.7262000000000004,"d":"3.726"},{"v":3.7109000000000005,"d":"3.711"},{"v":3.7077,"d":"3.708"},96.358,{"v":96.3626,"d":"96.363"},{"v":96.35679999999999,"d":"96.357"}]
["PDEG = 15%",{"v":10.430200000000001,"d":"10.430"},{"v":10.3736,"d":"10.374"},{"v":10.3567,"d":"10.357"},{"v":92.8072,"d":"92.807"},{"v":92.7856,"d":"92.786"},{"v":92.7323,"d":"92.732"}]
["PDEG = 25%",{"v":17.183300000000003,"d":"17.183"},{"v":17.1435,"d":"17.144"},{"v":17.0336,"d":"17.034"},{"v":89.2691,"d":"89.269"},{"v":89.2219,"d":"89.222"},{"v":89.1216,"d":"89.122"}]
["(e) iDEGES/TDT"]
["PDEG = 5%",{"v":2.2772,"d":"2.277"},{"v":2.2685,"d":"2.269"},{"v":2.2563,"d":"2.256"},{"v":96.1466,"d":"96.147"},{"v":96.1432,"d":"96.143"},{"v":96.1418,"d":"96.142"}]
["PDEG = 15%",{"v":7.3091,"d":"7.309"},{"v":7.2818,"d":"7.282"},{"v":7.1368,"d":"7.137"},{"v":91.6483,"d":"91.648"},{"v":91.6108,"d":"91.611"},{"v":91.47,"d":"91.470"}]
["PDEG = 25%",{"v":12.643799999999999,"d":"12.644"},{"v":12.524199999999999,"d":"12.524"},{"v":12.2295,"d":"12.230"},{"v":86.85979999999999,"d":"86.860"},{"v":86.7582,"d":"86.758"},{"v":86.4689,"d":"86.469"}]
["(f) iDEGES/DESeq"]
["PDEG = 5%",{"v":2.2799,"d":"2.280"},{"v":2.2686,"d":"2.269"},{"v":2.2571999999999997,"d":"2.257"},{"v":96.14580000000001,"d":"96.146"},{"v":96.1434,"d":"96.143"},{"v":96.14439999999999,"d":"96.144"}]
["PDEG = 15%",{"v":7.3073,"d":"7.307"},{"v":7.2881,"d":"7.288"},{"v":7.148899999999999,"d":"7.149"},{"v":91.64670000000001,"d":"91.647"},{"v":91.61749999999999,"d":"91.618"},{"v":91.4791,"d":"91.479"}]
["PDEG = 25%",{"v":12.6389,"d":"12.639"},{"v":12.5371,"d":"12.537"},{"v":12.245000000000001,"d":"12.245"},{"v":86.8575,"d":"86.858"},{"v":86.7713,"d":"86.771"},86.489]