{"text_format":"3","workbook":"xls","n_sheets":4,"sheets":["standard procedure assignments","electron acceptor assignments ","additional manual assignments","model"],"not_rendered":{"external_links":1},"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"standard procedure assignments","index":0,"n_rows":927,"n_cols":23,"rows_kept":927,"merged":[[3,4,4,4],[3,6,3,8],[6,16,6,18]],"flags":["formulas_cached_only"]}
[]
[]
[]
[{"$nulls":4},"thermodynamic facts",null,"topology and thermodynamically heuristic rules",{"$nulls":3},"summarized"]
[null,null,"reaction","reaction equation with original reaction directions",null,null,"pair cycles","remaining energy producing cycles","bypasses"]
[null,null,"ALATA_L","[c]akg + ala-L <==> glu-L + pyr","<=>",{"$nulls":5},"<=>",{"$nulls":3},"Comparison to original direction assignments"]
[null,null,"ALAR","[c]ala-L <==> ala-D",{"$nulls":12},"systematically/originally assigned"]
[null,null,"ASNN","[c]asn-L + h2o --> asp-L + nh4","-->",{"$nulls":5},"-->",{"$nulls":5},"<=> - <=>","-->/-->","<=>/-->"]
[null,null,"ASNS2","[c]asp-L + atp + nh4 --> amp + asn-L + h + ppi","<=>",null,"-->",{"$nulls":3},"-->",{"$nulls":3},"\"subset\"",914,238,124,552]
[null,null,"ASNS1","[c]asp-L + atp + gln-L + h2o --> amp + asn-L + glu-L + h + ppi","<=>",{"$nulls":5},"<=>",{"$nulls":3},"additionally irreversible",6]
[null,null,"ASPT","[c]asp-L --> fum + nh4","<=>",{"$nulls":5},"<=>",{"$nulls":3},"irreversible in opposite directions",0]
[null,null,"ASPTA","[c]akg + asp-L <==> glu-L + oaa","<=>",{"$nulls":5},"<=>"]
[null,null,"VPAMT","[c]3mob + ala-L --> pyr + val-L"]
[null,null,"DAAD","[c]ala-D + fad + h2o --> fadh2 + nh4 + pyr",{"$nulls":10},"additionals:","reaction","reaction equation",{"$nulls":4},"assignment","note"]
[null,null,"FFSD","[c]h2o + suc6p --> fru + g6p",{"$nulls":10},42,"GALU","[c]g1p + h + utp <==> ppi + udpg",{"$nulls":4},"-->","irreversible according to EcoCyc"]
[null,null,"A5PISO","[c]ru5p-D <==> ara5p","<=>",{"$nulls":5},"<=>",{"$nulls":3},479,"DASYN_EC","[c]ctp + h + (0.02) pa_EC <==> (0.02) cdpdag1 + ppi",{"$nulls":4},"-->","de facto irreversible in original model"]
[null,null,"MME","[c]mmcoa-R <==> mmcoa-S","<=>",{"$nulls":5},"<=>",{"$nulls":3},658,"PRASCS","[c]5aizc + asp-L + atp <==> 25aics + adp + h + pi",{"$nulls":4},"-->","de facto irreversible in original model"]
[null,null,"MICITD","[c]2mcacn + h2o --> micit",{"$nulls":10},659,"PRAGSr","[c]atp + gly + pram <==> adp + gar + h + pi",{"$nulls":4},"-->","de facto irreversible in original model"]
[null,null,"ALCD19","[c]glyald + h + nadh <==> glyc + nad","<=>",{"$nulls":5},"<=>",{"$nulls":3},717,"ASPK","[c]asp-L + atp <==> 4pasp + adp",{"$nulls":4},"-->","de facto irreversible in original model"]
[null,null,"TGBPA","[c]tagdp-D <==> dhap + g3p",{"$nulls":10},421,"SULR","[c](3) h2o + h2s + (3) nadp <==> (5) h + (3) nadph + so3",{"$nulls":4},"<--","de facto irreversible in original model"]
[null,null,"LCAD","[c]h2o + lald-L + nad <==> (2) h + lac-L + nadh"]
[null,null,"ALDD2x","[c]acald + h2o + nad --> ac + (2) h + nadh","-->",{"$nulls":5},"-->"]
[null,null,"ARAI","[c]arab-L <==> rbl-L","<=>",{"$nulls":5},"<=>"]
[null,null,"RBK_L1","[c]atp + rbl-L --> adp + h + ru5p-L","<=>",{"$nulls":5},"<=>"]
[null,null,"RBP4E","[c]ru5p-L <==> xu5p-D"]
[null,null,"ACACCT","[c]acac + accoa --> aacoa + ac","<=>",{"$nulls":5},"<=>"]
[null,null,"BUTCT","[c]accoa + but --> ac + btcoa"]
[null,null,"AB6PGH","[c]arbt6p + h2o --> g6p + hqn"]
[null,null,"PMANM","[c]man1p <==> man6p","<=>",{"$nulls":5},"<=>"]
[null,null,"PPM2","[c]2dr1p <==> 2dr5p","<=>",{"$nulls":5},"<=>"]
[null,null,"PPM","[c]r1p <==> r5p","<=>",{"$nulls":5},"<=>"]
[null,null,"DRPA","[c]2dr5p --> acald + g3p","<=>",{"$nulls":5},"<=>"]
[null,null,"GALCTND","[c]galctn-D --> 2dh3dgal + h2o"]
[null,null,"DDPGALA","[c]2dh3dgal6p <==> g3p + pyr"]
[null,null,"DDGALK","[c]2dh3dgal + atp --> 2dh3dgal6p + adp + h"]
[null,null,"DHAPT","[c]dha + pep --> dhap + pyr","-->",{"$nulls":5},"-->"]
[null,null,"FAO4","[c]btcoa + fad + h2o + nad --> aacoa + fadh2 + h + nadh"]
[null,null,"ALDD19x","[c]h2o + nad + pacald --> (2) h + nadh + pac"]
[null,null,"FRUK","[c]atp + f1p --> adp + fdp + h",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"FCLPA","[c]fc1p <==> dhap + lald-L"]
[null,null,"FCI","[c]fuc-L <==> fcl-L"]
[null,null,"FCLK","[c]atp + fcl-L --> adp + fc1p + h"]
[null,null,"LCAR","[c]h + lald-L + nadh <==> 12ppd-S + nad"]
[null,null,"UDPG4E","[c]udpg <==> udpgal"]
[null,null,"GALKr","[c]atp + gal <==> adp + gal1p + h","<=>",{"$nulls":5},"<=>"]
[null,null,"UGLT","[c]gal1p + udpg <==> g1p + udpgal"]
[null,null,"GALU","[c]g1p + h + utp <==> ppi + udpg",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"GALCTD","[c]galct-D --> 5dh4dglc + h2o"]
[null,null,"GLTPD","[c]galt1p + nad <==> h + nadh + tag6p-D"]
[null,null,"GLYCTO2","[c]glyclt + q8 --> glx + q8h2","<=>",{"$nulls":5},"<=>"]
[null,null,"GLYCTO3","[c]glyclt + mqn8 --> glx + mql8","<=>",{"$nulls":5},"<=>"]
[null,null,"GLYCTO4","[c]2dmmq8 + glyclt --> 2dmmql8 + glx","<=>",{"$nulls":5},"<=>"]
[null,null,"GLYCDx","[c]glyc + nad --> dha + h + nadh","<=>",{"$nulls":5},"<=>"]
[null,null,"GLYK","[c]atp + glyc --> adp + glyc3p + h","<=>",null,null,"-->",null,null,"<=>"]
[null,null,"PGLYCP","[c]2pglyc + h2o --> glyclt + pi"]
[null,null,"G3PD2","[c]glyc3p + nadp <==> dhap + h + nadph","<=>",{"$nulls":5},"<=>"]
[null,null,"GLCRAL","[c]5dh4dglc --> 2h3oppan + pyr"]
[null,null,"DHPPD","[c]cechddd + nad --> dhpppn + h + nadh"]
[null,null,"DHCIND","[c]cenchddd + nad --> dhcinnm + h + nadh"]
[null,null,"PPPNDO","[c]h + nadh + o2 + pppn --> cechddd + nad"]
[null,null,"CINNDO","[c]cinnm + h + nadh + o2 --> cenchddd + nad"]
[null,null,"HPYRI","[c]hpyr <==> 2h3oppan"]
[null,null,"IDOND","[c]5dglcn + h + nadh <==> idon-L + nad"]
[null,null,"IDOND2","[c]5dglcn + h + nadph --> idon-L + nadp"]
[null,null,"GNK","[c]atp + glcn --> 6pgc + adp + h",{"$nulls":4},"-->",null,"-->"]
[null,null,"5DGLCNR","[c]5dglcn + h + nadph <==> glcn + nadp"]
[null,null,"DDGLK","[c]2ddglcn + atp --> 2ddg6p + adp + h"]
[null,null,"LACZ","[c]h2o + lcts --> gal + glc-D","-->",{"$nulls":5},"-->"]
[null,null,"MLTP1","[c]maltpt + pi <==> g1p + maltttr"]
[null,null,"MLTP2","[c]malthx + pi <==> g1p + maltpt"]
[null,null,"MLTP3","[c]malthp + pi <==> g1p + malthx"]
[null,null,"AMALT1","[c]malt + malttr --> glc-D + maltttr"]
[null,null,"AMALT2","[c]malt + maltttr --> glc-D + maltpt"]
[null,null,"AMALT3","[c]malt + maltpt --> glc-D + malthx"]
[null,null,"AMALT4","[c]malt + malthx --> glc-D + malthp"]
[null,null,"MLTG1","[c]h2o + malttr --> glc-D + malt"]
[null,null,"MLTG2","[c]h2o + maltttr --> glc-D + malttr"]
[null,null,"MLTG3","[c]h2o + maltpt --> glc-D + maltttr"]
[null,null,"MLTG4","[c]h2o + malthx --> glc-D + maltpt"]
[null,null,"MLTG5","[c]h2o + malthp --> glc-D + malthx"]
[null,null,"MAN6PI","[c]man6p <==> f6p","<=>",{"$nulls":5},"<=>"]
[null,null,"GALS3","[c]h2o + melib --> gal + glc-D"]
[null,null,"3HCINNMH","[c]3hcinnm + h + nadh + o2 --> dhcinnm + h2o + nad"]
[null,null,"3HPPPNH","[c]3hpppn + h + nadh + o2 --> dhpppn + h2o + nad"]
[null,null,"DHCINDO","[c]dhcinnm + o2 --> hkntd"]
[null,null,"HPPPNDO","[c]dhpppn + o2 --> hkndd"]
[null,null,"HKNDDH","[c]h2o + hkndd --> (2) h + op4en + succ"]
[null,null,"HKNTDH","[c]h2o + hkntd --> fum + (2) h + op4en"]
[null,null,"OP4ENH","[c]h2o + op4en --> 4h2opntn"]
[null,null,"HOPNTAL","[c]4h2opntn --> acald + pyr"]
[null,null,"ACALDi","[c]acald + coa + nad --> accoa + h + nadh","<=>",{"$nulls":5},"<=>"]
[null,null,"M1PD","[c]mnl1p + nad <==> f6p + h + nadh","<=>",{"$nulls":5},"<=>"]
[null,null,"AGDC","[c]acgam6p + h2o --> ac + gam6p"]
[null,null,"G6PDA","[c]gam6p + h2o --> f6p + nh4"]
[null,null,"ACNML","[c]acnam --> acmana + pyr"]
[null,null,"TRE6PS","[c]g6p + udpg --> h + tre6p + udp"]
[null,null,"TRE6PP","[c]h2o + tre6p --> pi + tre"]
[null,null,"PACCOAL","[c]atp + coa + pac --> amp + phaccoa + ppi"]
[null,null,"PFK_2","[c]atp + tag6p-D --> adp + h + tagdp-D"]
[null,null,"PGMT","[c]g1p <==> g6p","<=>",{"$nulls":5},"<=>"]
[null,null,"MCITL2","[c]micit <==> pyr + succ"]
[null,null,"MCITS","[c]h2o + oaa + ppcoa --> 2mcit + coa + h"]
[null,null,"MCITD","[c]2mcit --> 2mcacn + h2o"]
[null,null,"ACCOAL","[c]atp + coa + ppa --> adp + pi + ppcoa"]
[null,null,"PTA2","[c]pi + ppcoa --> coa + ppap"]
[null,null,"RBK","[c]atp + rib-D --> adp + h + r5p","<=>",{"$nulls":5},"<=>"]
[null,null,"RMI","[c]rmn <==> rml"]
[null,null,"RMK","[c]atp + rml --> adp + h + rml1p"]
[null,null,"RMPA","[c]rml1p <==> dhap + lald-L"]
[null,null,"MMM2","[c]succoa --> mmcoa-R","<=>",{"$nulls":5},"<=>"]
[null,null,"KG6PDC","[c]3dgulnp + h + h2o --> co2tot + xu5p-L"]
[null,null,"X5PL3E","[c]xu5p-L --> ru5p-L","<=>",{"$nulls":5},"<=>"]
[null,null,"SBTPD","[c]nad + sbt6p <==> f6p + h + nadh","<=>",{"$nulls":5},"<=>"]
[null,null,"TAUDO","[c]akg + o2 + taur + h2o --> aacald + co2tot + h + so3 + succ"]
[null,null,"PPAKr","[c]adp + ppap <==> atp + ppa"]
[null,null,"OBTFL","[c]2obut + coa --> for + ppcoa",{"$nulls":4},"-->",null,"-->"]
[null,null,"TREHe","[e]h2o + tre --> (2) glc-D"]
[null,null,"TRE6PH","[c]h2o + tre6p --> g6p + glc-D"]
[null,null,"TREH","[c]h2o + tre --> (2) glc-D","-->",{"$nulls":5},"-->"]
[null,null,"TARTD","[c]tartr-L --> h2o + oaa"]
[null,null,"PEAMNO","[c]h2o + o2 + peamn --> h2o2 + nh4 + pacald"]
[null,null,"ALTRH","[c]altrn --> 2ddglcn + h2o"]
[null,null,"TAGURr","[c]altrn + nad <==> h + nadh + tagur"]
[null,null,"GUI1","[c]glcur <==> fruur"]
[null,null,"GUI2","[c]galur <==> tagur"]
[null,null,"MNNH","[c]mana --> 2ddglcn + h2o"]
[null,null,"MANAO","[c]mana + nad <==> fruur + h + nadh"]
[null,null,"XYLI2i","[c]fru --> glc-D","<=>",{"$nulls":5},"<=>"]
[null,null,"XYLI1","[c]xyl-D <==> xylu-D","<=>",{"$nulls":5},"<=>"]
[null,null,"XYLK","[c]atp + xylu-D --> adp + h + xu5p-D"]
[null,null,"DKGLCNR1","[c]25dkglcn + h + nadph --> 2dhguln + nadp"]
[null,null,"HPYRRx","[c]h + hpyr + nadh --> glyc-R + nad","<=>",{"$nulls":5},"<=>"]
[null,null,"HPYRRy","[c]h + hpyr + nadph --> glyc-R + nadp","<=>",{"$nulls":5},"<=>"]
[null,null,"GLCRD","[c]glcr --> 5dh4dglc + h2o"]
[null,null,"MMCD","[c]h + mmcoa-S + h2o --> co2tot + ppcoa","-->",{"$nulls":5},"-->"]
[null,null,"PPCSCT","[c]ppcoa + succ --> ppa + succoa"]
[null,null,"DKGLCNR2y","[c]25dkglcn + h + nadph --> 5dglcn + nadp"]
[null,null,"2DGLCNRx","[c]2dhglcn + h + nadh --> glcn + nad"]
[null,null,"2DGLCNRy","[c]2dhglcn + h + nadph --> glcn + nadp"]
[null,null,"DKGLCNR2x","[c]25dkglcn + h + nadh --> 5dglcn + nad"]
[null,null,"2DGULRx","[c]2dhguln + h + nadh --> idon-L + nad"]
[null,null,"2DGULRy","[c]2dhguln + h + nadph --> idon-L + nadp"]
[null,null,"DOGULNR","[c]23doguln + h + nadh --> 3dhguln + nad"]
[null,null,"ICL","[c]icit --> glx + succ","<=>",{"$nulls":5},"<=>"]
[null,null,"MALS","[c]accoa + glx + h2o --> coa + h + mal-L","-->",{"$nulls":5},"-->"]
[null,null,"ME2","[c]mal-L + nadp + h2o --> co2tot + nadph + pyr","<=>",{"$nulls":5},"<=>"]
[null,null,"PPCK","[c]atp + oaa + h2o --> adp + co2tot + pep","<=>",{"$nulls":5},"<=>"]
[null,null,"PPA","[c]h2o + ppi --> h + (2) pi","-->",{"$nulls":5},"-->"]
[null,null,"PPC","[c]co2tot + pep --> h + oaa + pi","-->",{"$nulls":5},"-->"]
[null,null,"ME1","[c]mal-L + nad + h2o --> co2tot + nadh + pyr","<=>",{"$nulls":5},"<=>"]
[null,null,"MDRPD","[c]5mdru1p --> dkmpp + h2o"]
[null,null,"DKMPPD2","[c]dkmpp + (3) h2o --> 2kmb + for + (6) h + pi"]
[null,null,"PTRCTA","[c]akg + ptrc --> 4abutn + glu-L"]
[null,null,"SSALx","[c]h2o + nad + sucsal --> (2) h + nadh + succ"]
[null,null,"ABUTD","[c]4abutn + h2o + nad --> 4abut + (2) h + nadh"]
[null,null,"MTRK","[c]5mtr + atp --> 5mdr1p + adp + h"]
[null,null,"MTRI","[c]5mdr1p <==> 5mdru1p"]
[null,null,"DKMPPD","[c]dkmpp + h2o + o2 --> 2kmb + for + (2) h + pi"]
[null,null,"G5SADs","[c]glu5sa --> 1pyr5c + h + h2o"]
[null,null,"UNK3","[c]2kmb + glu-L --> akg + met-L"]
[null,null,"ACGS","[c]accoa + glu-L --> acglu + coa + h"]
[null,null,"ACGK","[c]acglu + atp --> acg5p + adp",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"AGPR","[c]acg5sa + nadp + pi <==> acg5p + h + nadph"]
[null,null,"ACOTA","[c]acorn + akg <==> acg5sa + glu-L"]
[null,null,"NACODA","[c]acg5sa + h2o --> ac + glu5sa"]
[null,null,"ACODA","[c]acorn + h2o --> ac + orn"]
[null,null,"ARGSS","[c]asp-L + atp + citr-L --> amp + argsuc + h + ppi"]
[null,null,"ARGSL","[c]argsuc <==> arg-L + fum"]
[null,null,"OCBT","[c]cbp + orn <==> citr-L + h + pi"]
[null,null,"AST","[c]arg-L + succoa --> coa + h + sucarg"]
[null,null,"SOTA","[c]akg + sucorn --> glu-L + sucgsa"]
[null,null,"SADH","[c](2) h + (3) h2o + sucarg --> co2tot + (2) nh4 + sucorn",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"SGSAD","[c]h2o + nad + sucgsa --> (2) h + nadh + sucglu"]
[null,null,"SGDS","[c]h2o + sucglu --> glu-L + succ"]
[null,null,"CBPS","[c](2) atp + gln-L + h2o + hco3 --> (2) adp + cbp + glu-L + (2) h + pi"]
[null,null,"SSALy","[c]h2o + nadp + sucsal --> (2) h + nadph + succ"]
[null,null,"ABTA","[c]4abut + akg --> glu-L + sucsal"]
[null,null,"GSPMDA","[c]gtspmd + h2o --> gthrd + spmd"]
[null,null,"GSPMDS","[c]atp + gthrd + spmd --> adp + gtspmd + h + pi",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"MTAN","[c]5mta + h2o --> 5mtr + ade"]
[null,null,"G5SD","[c]glu5p + h + nadph --> glu5sa + nadp + pi"]
[null,null,"GLU5K","[c]atp + glu-L --> adp + glu5p",{"$nulls":4},"-->",null,"-->"]
[null,null,"P5CR","[c]1pyr5c + (2) h + nadph --> nadp + pro-L"]
[null,null,"P5CD","[c]1pyr5c + (2) h2o + nad --> glu-L + h + nadh"]
[null,null,"PROD2","[c]fad + pro-L --> 1pyr5c + fadh2 + h"]
[null,null,"ARGDC","[c]arg-L + h + h2o --> agm + co2tot"]
[null,null,"AGMT","[c]agm + h2o --> ptrc + urea"]
[null,null,"ORNDC","[c]h + orn + h2o --> co2tot + ptrc",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"ADMDCr","[c]amet + h + h2o <==> ametam + co2tot"]
[null,null,"SPMS","[c]ametam + ptrc --> 5mta + h + spmd"]
[null,null,"SPMDAT1","[c]accoa + spmd --> N1aspmd + coa + h"]
[null,null,"SPMDAT2","[c]accoa + spmd --> coa + h + n8aspmd"]
[null,null,"ORNTA","[c]akg + orn --> glu-L + glu5sa"]
[null,null,"PPTGS","[c]uaagmda --> h + peptido_EC + udcpdp"]
[null,null,"UDCPDP","[c]h2o + udcpdp --> h + pi + udcpp"]
[null,null,"KDOPP","[c]h2o + kdo8p --> kdo + pi"]
[null,null,"PEPT_EC","[c]cmp + h + (0.02) pe_EC <==> (0.02) 12dgr_EC + cdpea"]
[null,null,"PAPA_EC","[c]h2o + (0.02) pa_EC --> (0.02) 12dgr_EC + pi"]
[null,null,"ECAP_EC","[c]unagamuf --> eca_EC + h + udcpdp"]
[null,null,"AACPS1","[c]ACP + atp + ttdca --> amp + myrsACP + ppi",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"AACPS2","[c]ACP + atp + ttdcea --> amp + ppi + tdeACP",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"AACPS3","[c]ACP + atp + hdca --> amp + palmACP + ppi",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"AACPS4","[c]ACP + atp + hdcea --> amp + hdeACP + ppi",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"AACPS5","[c]ACP + atp + ocdcea --> amp + octeACP + ppi",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"ALAALAr","[c](2) ala-D + atp <==> adp + alaala + h + pi"]
[null,null,"DAGK_EC","[c](0.02) 12dgr_EC + atp --> adp + h + (0.02) pa_EC",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"ETHAAL","[c]etha --> acald + nh4"]
[null,null,"GDMANE","[c]gdpddman --> gdpofuc"]
[null,null,"GOFUCR","[c]gdpofuc + h + nadph --> gdpfuc + nadp"]
[null,null,"UDPGALM","[c]udpgal --> udpgalfur"]
[null,null,"GF6PTA","[c]f6p + gln-L --> gam6p + glu-L"]
[null,null,"UAGDP","[c]acgam1p + h + utp --> ppi + uacgam"]
[null,null,"G1PACT","[c]accoa + gam1p --> acgam1p + coa + h"]
[null,null,"GPDDA1","[c]g3pc + h2o --> chol + glyc3p + h"]
[null,null,"GPDDA2","[c]g3pe + h2o --> etha + glyc3p + h"]
[null,null,"GPDDA3","[c]g3ps + h2o --> glyc3p + h + ser-L"]
[null,null,"GPDDA4","[c]g3pg + h2o --> glyc + glyc3p + h"]
[null,null,"GPDDA5","[c]g3pi + h2o --> glyc3p + h + inost"]
[null,null,"GMAND","[c]gdpmann --> gdpddman + h2o"]
[null,null,"S7PI","[c]s7p --> gmhep7p"]
[null,null,"GMHEPPA","[c]gmhep17bp + h2o --> gmhep1p + pi"]
[null,null,"KDOPS","[c]ara5p + h2o + pep --> kdo8p + pi"]
[null,null,"KDOCT2","[c]ctp + kdo --> ckdo + ppi"]
[null,null,"MOAT","[c]ckdo + lipidA --> cmp + h + kdolipid4"]
[null,null,"MOAT2","[c]ckdo + kdolipid4 --> cmp + h + kdo2lipid4"]
[null,null,"UAGAAT","[c]3hmrsACP + uacgam <==> ACP + u3aga"]
[null,null,"LPADSS","[c]lipidX + u23ga --> h + lipidAds + udp"]
[null,null,"UHGADA","[c]h2o + u3aga --> ac + u3hga"]
[null,null,"U23GAAT","[c]3hmrsACP + u3hga --> ACP + h + u23ga"]
[null,null,"TDSK","[c]atp + lipidAds --> adp + h + lipidA"]
[null,null,"EDTXS1","[c]ddcaACP + kdo2lipid4 --> ACP + kdo2lipid4L"]
[null,null,"EDTXS3","[c]hdeACP + kdo2lipid4 --> ACP + kdo2lipid4p"]
[null,null,"MAN1PT2","[c]gdp + h + man1p --> gdpmann + pi"]
[null,null,"PAPPT3","[c]udcpp + ugmda --> uagmda + ump"]
[null,null,"PGAMT","[c]gam1p <==> gam6p"]
[null,null,"EDTXS4","[c]kdo2lipid4p + myrsACP --> ACP + lipa_cold"]
[null,null,"EDTXS2","[c]kdo2lipid4L + myrsACP --> ACP + lipa"]
[null,null,"UAGCVT","[c]pep + uacgam --> pi + uaccg"]
[null,null,"UAPGR","[c]h + nadph + uaccg --> nadp + uamr"]
[null,null,"UAMAS","[c]ala-L + atp + uamr --> adp + h + pi + uama"]
[null,null,"UAMAGS","[c]atp + glu-D + uama --> adp + h + pi + uamag"]
[null,null,"UAAGDS","[c]26dap-M + atp + uamag --> adp + h + pi + ugmd"]
[null,null,"UGMDDS","[c]alaala + atp + ugmd --> adp + h + pi + ugmda"]
[null,null,"UAGPT3","[c]uacgam + uagmda --> h + uaagmda + udp"]
[null,null,"GLUR","[c]glu-D <==> glu-L"]
[null,null,"PLIPA3","[c]h2o + (0.02) pc_EC --> (0.02) agpc_EC + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[null,null,"PLIPA1","[c]h2o + (0.02) pg_EC --> (0.02) agpg_EC + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[null,null,"PLIPA2","[c]h2o + (0.02) pe_EC --> (0.02) agpe_EC + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[null,null,"LPLIPA1","[c](0.02) agpg_EC + h2o --> g3pg + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[null,null,"LPLIPA2","[c](0.02) agpe_EC + h2o --> g3pe + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[null,null,"LPLIPA3","[c](0.02) agpc_EC + h2o --> g3pc + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[null,null,"LPLIPA4","[c](0.02) agpe_EC + (0.02) pg_EC --> (0.02) apg_EC + g3pe"]
[null,null,"LPLIPA5","[c](0.02) agpc_EC + (0.02) pg_EC --> (0.02) apg_EC + g3pc"]
[null,null,"LPLIPA6","[c](0.02) agpg_EC + (0.02) pg_EC --> (0.02) apg_EC + g3pg"]
[null,null,"AGMHE","[c]adphep-D,D --> adphep-L,D"]
[null,null,"GMHEPAT","[c]atp + gmhep1p + h --> adphep-D,D + ppi"]
[null,null,"GMHEPK","[c]atp + gmhep7p --> adp + gmhep17bp + h"]
[null,null,"LPSSYN_EC","[c](3) adphep-L,D + (2) cdpea + (3) ckdo + lipa + (2) udpg --> (3) adp + (2) cdp + (3) cmp + (10) h + lps_EC + (2) udp"]
[null,null,"G1PTT","[c]dttp + g1p + h --> dtdpglu + ppi"]
[null,null,"TDPGDH","[c]dtdpglu --> dtdp4d6dg + h2o"]
[null,null,"TDPDRE","[c]dtdp4d6dg --> dtdp4d6dm"]
[null,null,"TDPDRR","[c]dtdp4d6dm + h + nadph --> dtdprmn + nadp"]
[null,null,"MI1PP","[c]h2o + mi1p-D --> inost + pi"]
[null,null,"UDPGD","[c]h2o + (2) nad + udpg --> (3) h + (2) nadh + udpglcur"]
[null,null,"USHD","[c]h2o + u23ga --> (2) h + lipidX + ump"]
[null,null,"ACGAMT","[c]uacgam + udcpp --> ump + unaga"]
[null,null,"UAG2Ei","[c]uacgam --> uacmam"]
[null,null,"UACMAMO","[c]h2o + (2) nad + uacmam --> (3) h + (2) nadh + uacmamu"]
[null,null,"TDPADGAT","[c]accoa + dtdp4addg --> coa + dtdp4aaddg + h"]
[null,null,"TDPAGTA","[c]dtdp4d6dg + glu-L --> akg + dtdp4addg"]
[null,null,"AADDGT","[c]dtdp4aaddg + unagamu --> dtdp + h + unagamuf"]
[null,null,"ACMAMUT","[c]uacmamu + unaga --> h + udp + unagamu"]
[null,null,"ACONT","[c]cit <==> icit","<=>",{"$nulls":5},"<=>"]
[null,null,"CITL","[c]cit --> ac + oaa","<=>",{"$nulls":5},"<=>"]
[null,null,"FRD2","[c]fum + mql8 --> mqn8 + succ","<=>",{"$nulls":5},"<=>"]
[null,null,"FRD3","[c]2dmmql8 + fum --> 2dmmq8 + succ","<=>",{"$nulls":5},"<=>"]
[null,null,"FUM","[c]fum + h2o <==> mal-L","<=>",{"$nulls":5},"<=>"]
[null,null,"CS","[c]accoa + h2o + oaa --> cit + coa + h","-->",{"$nulls":5},"-->"]
[null,null,"ICDHyr","[c]icit + nadp + h2o <==> akg + co2tot + nadph","<=>",null,null,"-->",null,null,"<=>"]
[null,null,"TEST_AKGDH","[c]akg + coa + nad + h2o --> co2tot + nadh + succoa","<=>",{"$nulls":5},"<=>"]
[null,null,"MDH","[c]mal-L + nad <==> h + nadh + oaa","<=>",{"$nulls":5},"<=>"]
[null,null,"MDH2","[c]mal-L + q8 --> oaa + q8h2","<=>",{"$nulls":5},"<=>"]
[null,null,"MDH3","[c]mal-L + mqn8 --> mql8 + oaa","<=>",{"$nulls":5},"<=>"]
[null,null,"SUCD1i","[c]fad + succ --> fadh2 + fum","<=>",{"$nulls":5},"<=>"]
[null,null,"SUCOAS","[c]atp + coa + succ <==> adp + pi + succoa","<=>",{"$nulls":5},"<=>"]
[null,null,"PMDPHT","[c]5aprbu + h2o --> 4r5au + pi"]
[null,null,"DNMPPA","[c]dhpmp + h2o --> dhnpt + pi"]
[null,null,"NADPPPS","[c]h2o + nadp --> nad + pi","-->",{"$nulls":5},"-->"]
[null,null,"NMNN","[c]h2o + nmn --> h + ncam + r5p"]
[null,null,"NADDPe","[e]h2o + nad --> amp + (2) h + nmn"]
[null,null,"PPCDC","[c]4ppcys + h +h2o --> co2tot + pan4p"]
[null,null,"DPCOAK","[c]atp + dpcoa --> adp + coa + h"]
[null,null,"HYPOE","[c]h2o + pyam5p --> pi + pydam"]
[null,null,"PYDXPP","[c]h2o + pydx5p --> pi + pydx"]
[null,null,"PDXPP","[c]h2o + pdx5p --> pi + pydxn"]
[null,null,"NMNDA","[c]h2o + nmn --> nh4 + nicrnt"]
[null,null,"TMKr","[c]atp + thm <==> adp + h + thmmp"]
[null,null,"PPNCL2","[c]4ppan + ctp + cys-L --> 4ppcys + cmp + h + ppi"]
[null,null,"ACPS1","[c]apoACP + coa --> ACP + h + pap"]
[null,null,"AMAOTr","[c]8aonn + amet <==> amob + dann"]
[null,null,"BTS2","[c]cys-L + dtbt <==> ala-L + btn + (2) h"]
[null,null,"DBTSr","[c]atp + co2tot + dann <==> adp + dtbt + (3) h + pi + h2o"]
[null,null,"AOXSr","[c]ala-L + h + pmcoa + h2o <==> 8aonn + co2tot + coa"]
[null,null,"BSORx","[c]btnso + h + nadh --> btn + h2o + nad"]
[null,null,"BSORy","[c]btnso + h + nadph --> btn + h2o + nadp"]
[null,null,"CBIAT","[c]atp + cbi + h2o <==> adocbi + pi + ppi"]
[null,null,"CBLAT","[c]atp + cbl1 + h2o <==> adocbl + pi + ppi"]
[null,null,"PNTK","[c]atp + pnto-R --> 4ppan + adp + h"]
[null,null,"PTPATi","[c]atp + h + pan4p --> dpcoa + ppi"]
[null,null,"ADOCBLS","[c]agdpcbi + rdmbzi --> adocbl + gmp + h"]
[null,null,"NNDMBRT","[c]dmbzid + nicrnt --> 5prdmbz + h + nac"]
[null,null,"ADOCBIK","[c]adocbi + atp --> adocbip + adp + h"]
[null,null,"ACBIPGT","[c]adocbip + gtp + h --> agdpcbi + ppi"]
[null,null,"HEMEOS","[c]frdp + h2o + pheme --> hemeO + ppi"]
[null,null,"SHCHD2","[c]nad + shcl --> h + nadh + srch"]
[null,null,"SHCHF","[c]fe2 + srch --> (3) h + sheme"]
[null,null,"DXPRIi","[c]dxyl5p + h + nadph --> 2me4p + nadp"]
[null,null,"DXPS","[c]g3p + h + pyr + h2o --> co2tot + dxyl5p"]
[null,null,"DHBD","[c]23ddhb + nad <==> 23dhb + h + nadh"]
[null,null,"ICHORT","[c]h2o + ichor --> 23ddhb + pyr"]
[null,null,"ENTCS","[c](3) 23dhba + (3) seramp --> (6) amp + enter + (6) h"]
[null,null,"DHBSr","[c]23dhb + atp <==> 23dhba + ppi"]
[null,null,"SERASr","[c]atp + h + ser-L <==> ppi + seramp"]
[null,null,"E4PD","[c]e4p + h2o + nad <==> 4per + (2) h + nadh"]
[null,null,"DHFR","[c]dhf + h + nadph <==> nadp + thf"]
[null,null,"DHNPA2","[c]dhnpt --> 6hmhpt + gcald"]
[null,null,"DHFS","[c]atp + dhpt + glu-L --> adp + dhf + pi"]
[null,null,"GTPCI","[c]gtp + h2o --> ahdt + for"]
[null,null,"HPPK2","[c]6hmhpt + atp --> 6hmhptpp + amp + h"]
[null,null,"DHPS2","[c]4abz + 6hmhptpp --> dhpt + h + ppi"]
[null,null,"MECDPDH","[c]2mecdp + h --> h2mb4p + h2o"]
[null,null,"GLUTRS","[c]atp + glu-L + trnaglu --> amp + glutrna + ppi"]
[null,null,"ALATA_D2","[c]ala-D + pydx5p --> pyam5p + pyr"]
[null,null,"ALATA_L2","[c]ala-L + pydx5p --> pyam5p + pyr"]
[null,null,"GTHOr","[c]gthox + h + nadph <==> (2) gthrd + nadp","<=>",{"$nulls":5},"<=>"]
[null,null,"GLUCYS","[c]atp + cys-L + glu-L --> adp + glucys + h + pi"]
[null,null,"GTHS","[c]atp + glucys + gly --> adp + gthrd + h + pi"]
[null,null,"GLUTRR","[c]glutrna + h + nadph --> glu1sa + nadp + trnaglu"]
[null,null,"PPBNGS","[c](2) 5aop --> h + (2) h2o + ppbng"]
[null,null,"HMBS","[c]h2o + (4) ppbng --> hmbil + (4) nh4"]
[null,null,"UPP3S","[c]hmbil --> h2o + uppg3"]
[null,null,"UPPDC1","[c](4) h + uppg3 + (4) h2o --> (4) co2tot + cpppg3"]
[null,null,"CPPPGO","[c]cpppg3 + (2) h + o2 --> (2) co2tot + pppg9"]
[null,null,"PPPGO","[c](1.5) o2 + pppg9 --> (3) h2o + ppp9"]
[null,null,"FCLT","[c]fe2 + ppp9 --> (2) h + pheme"]
[null,null,"G1SATi","[c]glu1sa --> 5aop"]
[null,null,"UPP3MT","[c](2) amet + uppg3 --> (2) ahcys + h + shcl"]
[null,null,"IPDDIi","[c]ipdp --> dmpp"]
[null,null,"DMATT","[c]dmpp + ipdp --> grdp + ppi"]
[null,null,"GRTT","[c]grdp + ipdp --> frdp + ppi"]
[null,null,"OCTDPS","[c]frdp + (5) ipdp --> octdp + (5) ppi"]
[null,null,"MEPCT","[c]2me4p + ctp + h --> 4c2me + ppi"]
[null,null,"CDPMEK","[c]4c2me + atp --> 2p4c2me + adp + h"]
[null,null,"MECDPS","[c]2p4c2me --> 2mecdp + cmp"]
[null,null,"NADDP","[c]h2o + nad --> amp + (2) h + nmn"]
[null,null,"DMPPS","[c]h + h2mb4p + nadh --> dmpp + h2o + nad"]
[null,null,"IPDPS","[c]h + h2mb4p + nadh --> h2o + ipdp + nad"]
[null,null,"DHNAOT","[c]dhna + octdp + h2o --> 2dmmq8 + co2tot + h + ppi"]
[null,null,"NPHS","[c]sbzcoa --> coa + dhna"]
[null,null,"SUCBZS","[c]2shchc --> h2o + sucbz"]
[null,null,"OXGDC2","[c]akg + h + thmpp + h2o --> co2tot + ssaltpp"]
[null,null,"SHCHCS2","[c]ichor + ssaltpp --> 2shchc + pyr + thmpp"]
[null,null,"SUCBZL","[c]atp + coa + sucbz --> amp + ppi + sbzcoa"]
[null,null,"ICHORSi","[c]chor --> ichor"]
[null,null,"AMMQT8_2","[c]2dmmq8 + amet --> ahcys + h + mqn8"]
[null,null,"QULNS","[c]dhap + iasp --> h + (2) h2o + pi + quln"]
[null,null,"ASPO3","[c]asp-L + q8 --> iasp + q8h2"]
[null,null,"ASPO4","[c]asp-L + mqn8 --> iasp + mql8"]
[null,null,"ASPO5","[c]asp-L + fum --> iasp + succ"]
[null,null,"ASPO6","[c]asp-L + o2 --> h2o2 + iasp"]
[null,null,"NNDPR","[c](2) h + prpp + quln + h2o --> co2tot + nicrnt + ppi",{"$nulls":4},"-->",null,"-->"]
[null,null,"NNAT","[c]atp + h + nicrnt --> dnad + ppi",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"NMNAT","[c]atp + h + nmn --> nad + ppi",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"NADS1","[c]atp + dnad + nh4 --> amp + h + nad + ppi",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"DNTPPA","[c]ahdt + h2o --> dhpmp + h + ppi"]
[null,null,"ADCS","[c]chor + gln-L --> 4adcho + glu-L"]
[null,null,"ADCL","[c]4adcho --> 4abz + h + pyr"]
[null,null,"MOHMT","[c]3mob + h2o + mlthf --> 2dhp + thf"]
[null,null,"PANTS","[c]ala-B + atp + pant-R --> amp + h + pnto-R + ppi"]
[null,null,"ASP1DC","[c]asp-L + h + h2o --> ala-B + co2tot"]
[null,null,"DPR","[c]2dhp + h + nadph --> nadp + pant-R"]
[null,null,"PDX5PS","[c]dxyl5p + nad + phthr --> co2tot + h + h2o + nadh + pdx5p + pi"]
[null,null,"PERD","[c]4per + nad <==> h + nadh + ohpb"]
[null,null,"PDX5PO","[c]o2 + pdx5p <==> h2o2 + pydx5p"]
[null,null,"PYAM5PO","[c]h2o + o2 + pyam5p --> h2o2 + nh4 + pydx5p"]
[null,null,"PYDXNK","[c]atp + pydxn --> adp + h + pdx5p",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"PYDAMK","[c]atp + pydam --> adp + h + pyam5p",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"PYDXK","[c]atp + pydx --> adp + h + pydx5p",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"RZ5PP","[c]5prdmbz + h2o --> pi + rdmbzi"]
[null,null,"NNAM","[c]h2o + ncam --> nac + nh4"]
[null,null,"NAMNPP","[c]atp + h2o + nac + prpp --> adp + nicrnt + pi + ppi",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"GTPCII2","[c]gtp + (3) h2o --> 25drapp + for + (2) h + ppi",{"$nulls":4},"-->",null,"-->"]
[null,null,"DB4PS","[c]ru5p-D --> db4p + for + h",{"$nulls":4},"-->",null,"-->"]
[null,null,"APRAUR","[c]5apru + h + nadph --> 5aprbu + nadp"]
[null,null,"DHPPDA2","[c]25drapp + h + h2o --> 5apru + nh4"]
[null,null,"RBFSa","[c]4r5au + db4p --> dmlz + (2) h2o + pi"]
[null,null,"RBFK","[c]atp + ribflv --> adp + fmn + h"]
[null,null,"FMNAT","[c]atp + fmn + h --> fad + ppi"]
[null,null,"RBFSb","[c](2) dmlz --> 4r5au + ribflv"]
[null,null,"OHPBAT","[c]glu-L + ohpb <==> akg + phthr"]
[null,null,"AMPMS","[c]air + h2o --> 4ampm + (2) for + (4) h"]
[null,null,"PMPK","[c]4ampm + atp --> 2mahmp + adp"]
[null,null,"HMPK1","[c]4ahmmp + atp --> 4ampm + adp + h"]
[null,null,"TMPPP","[c]2mahmp + 4mpetz + h --> ppi + thmmp"]
[null,null,"TMPKr","[c]atp + thmmp <==> adp + thmpp"]
[null,null,"HETZK","[c]4mhetz + atp --> 4mpetz + adp + h"]
[null,null,"THZPSN","[c]atp + cys-L + dxyl5p + tyr-L --> 4hba + 4mpetz + ala-L + amp + co2tot + h + ppi"]
[null,null,"4HTHRS","[c]h2o + phthr --> 4hthr + pi"]
[null,null,"HBZOPT","[c]4hbz + octdp --> 3ophb + ppi"]
[null,null,"OPHHX","[c]2oph + (0.5) o2 --> 2ohph"]
[null,null,"CHRPL","[c]chor --> 4hbz + pyr"]
[null,null,"OPHBDC","[c]3ophb + h + h2o --> 2oph + co2tot"]
[null,null,"OMBZLM","[c]2ombzl + amet --> 2ommbl + ahcys + h"]
[null,null,"OMMBLHX","[c]2ommbl + (0.5) o2 --> 2omhmbl"]
[null,null,"OHPHM","[c]2ohph + amet --> 2omph + ahcys + h"]
[null,null,"DMQMT","[c]2omhmbl + amet --> ahcys + h + q8h2"]
[null,null,"OMPHHX","[c]2omph + (0.5) o2 --> 2ombzl"]
[null,null,"UDCPDPS","[c]frdp + (8) ipdp --> (8) ppi + udcpdp"]
[null,null,"DXYLK","[c]atp + dxyl --> adp + dxyl5p + h"]
[null,null,"NADK","[c]atp + nad --> adp + h + nadp","<=>",{"$nulls":5},"<=>"]
[null,null,"BPNT","[c]h2o + pap --> amp + pi"]
[null,null,"ADSK","[c]aps + atp --> adp + h + paps"]
[null,null,"SADT2","[c]atp + gtp + h2o + so4 --> aps + gdp + pi + ppi","<=>",{"$nulls":5},"<=>"]
[null,null,"SERAT","[c]accoa + ser-L <==> acser + coa"]
[null,null,"PAPSR","[c]paps + trdrd --> (2) h + pap + so3 + trdox"]
[null,null,"SULR","[c](3) h2o + h2s + (3) nadp <==> (5) h + (3) nadph + so3","<--",{"$nulls":5},"<--"]
[null,null,"CYSS","[c]acser + h2s --> ac + cys-L + h"]
[null,null,"TRPAS1","[c]cys-L + h2o --> h2s + nh4 + pyr","-->",{"$nulls":5},"-->"]
[null,null,"GCALDD","[c]gcald + h2o + nad --> glyclt + (2) h + nadh"]
[null,null,"MTHFC","[c]h2o + methf <==> 10fthf"]
[null,null,"MTHFD","[c]mlthf + nadp <==> h + methf + nadph"]
[null,null,"GLYCL","[c]gly + nad + thf + h2o --> co2tot + mlthf + nadh + nh4",{"$nulls":4},"-->",null,"-->"]
[null,null,"MTHFR2","[c]h + mlthf + nadh --> 5mthf + nad"]
[null,null,"FTHFD","[c]10fthf + h2o --> for + h + thf",{"$nulls":4},"-->",null,"-->"]
[null,null,"GLUDC","[c]glu-L + h + h2o --> 4abut + co2tot",{"$nulls":4},"-->",null,"-->"]
[null,null,"GLUDy","[c]glu-L + h2o + nadp <==> akg + h + nadph + nh4","<=>",{"$nulls":5},"<=>"]
[null,null,"GLNS","[c]atp + glu-L + nh4 --> adp + gln-L + h + pi","<=>",{"$nulls":5},"<=>"]
[null,null,"GLUSy","[c]akg + gln-L + h + nadph --> (2) glu-L + nadp","<=>",null,null,"-->",null,null,"<=>"]
[null,null,"GLUN","[c]gln-L + h2o --> glu-L + nh4","-->",{"$nulls":5},"-->"]
[null,null,"SERD_D","[c]ser-D --> nh4 + pyr"]
[null,null,"GHMT2","[c]ser-L + thf --> gly + h2o + mlthf"]
[null,null,"GLYATi","[c]2aobut + coa --> accoa + gly"]
[null,null,"PGCD","[c]3pg + nad --> 3php + h + nadh","<=>",{"$nulls":5},"<=>"]
[null,null,"PSP_L","[c]h2o + pser-L --> pi + ser-L","<=>",{"$nulls":5},"<=>"]
[null,null,"PSERT","[c]3php + glu-L --> akg + pser-L","<=>",{"$nulls":5},"<=>"]
[null,null,"SERD_L","[c]ser-L --> nh4 + pyr","-->",{"$nulls":5},"-->"]
[null,null,"THRD","[c]nad + thr-L --> 2aobut + h + nadh"]
[null,null,"PDH","[c]coa + nad + pyr + h2o --> accoa + co2tot + nadh","<=>",{"$nulls":5},"<=>"]
[null,null,"G1PP","[c]g1p + h2o --> glc-D + pi","-->",{"$nulls":5},"-->"]
[null,null,"ENO","[c]2pg <==> h2o + pep","<=>",{"$nulls":5},"<=>"]
[null,null,"FBA","[c]fdp <==> dhap + g3p","<=>",{"$nulls":5},"<=>"]
[null,null,"FBP","[c]fdp + h2o --> f6p + pi","<=>",{"$nulls":5},"<=>"]
[null,null,"F6PA","[c]f6p <==> dha + g3p","<=>",{"$nulls":5},"<=>"]
[null,null,"GAPD","[c]g3p + nad + pi <==> 13dpg + h + nadh","<=>",{"$nulls":5},"<=>"]
[null,null,"GLCS1","[c]adpglc --> adp + glycogen + h"]
[null,null,"GLGC","[c]atp + g1p + h --> adpglc + ppi",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"GLCP","[c]glycogen + pi --> g1p"]
[null,null,"HEX1","[c]atp + glc-D --> adp + g6p + h","<=>",null,null,"-->",null,null,"<=>"]
[null,null,"PGM","[c]2pg <==> 3pg","<=>",{"$nulls":5},"<=>"]
[null,null,"PFK","[c]atp + f6p --> adp + fdp + h","<=>",null,"-->",{"$nulls":3},"-->"]
[null,null,"PGI","[c]g6p <==> f6p","<=>",{"$nulls":5},"<=>"]
[null,null,"PGK","[c]3pg + atp <==> 13dpg + adp","<=>",{"$nulls":5},"<=>"]
[null,null,"PPS","[c]atp + h2o + pyr --> amp + (2) h + pep + pi","<=>",{"$nulls":5},"<=>"]
[null,null,"PYK","[c]adp + h + pep --> atp + pyr","<=>",{"$nulls":5},"<=>"]
[null,null,"TPI","[c]dhap <==> g3p","<=>",{"$nulls":5},"<=>"]
[null,null,"TRSAR","[c]2h3oppan + h + nadh --> glyc-R + nad"]
[null,null,"GLXCL","[c](2) glx + h + h2o --> 2h3oppan + co2tot",{"$nulls":4},"-->",null,"-->"]
[null,null,"GLYCK","[c]atp + glyc-R --> 3pg + adp + h","<=>",{"$nulls":5},"<=>"]
[null,null,"GLYCLTDy","[c]glx + h + nadph --> glyclt + nadp","<=>",{"$nulls":5},"<=>"]
[null,null,"GLYCLTDx","[c]glx + h + nadh --> glyclt + nad","<=>",{"$nulls":5},"<=>"]
[null,null,"PRMICIi","[c]prfp --> prlp"]
[null,null,"IGPDH","[c]eig3p --> h2o + imacp"]
[null,null,"HISTP","[c]h2o + hisp --> histd + pi"]
[null,null,"HSTPT","[c]glu-L + imacp --> akg + hisp"]
[null,null,"HISTD","[c]h2o + histd + (2) nad --> (3) h + his-L + (2) nadh"]
[null,null,"IG3PS","[c]gln-L + prlp --> aicar + eig3p + glu-L + h"]
[null,null,"ATPPRT","[c]atp + prpp --> ppi + prbatp"]
[null,null,"PRATPP","[c]h2o + prbatp --> h + ppi + prbamp"]
[null,null,"PRAMPC","[c]h2o + prbamp --> prfp"]
[null,null,"PRPPS","[c]atp + r5p <==> amp + h + prpp","<=>",null,null,"-->",null,null,"<=>"]
[null,null,"ACCOACr","[c]accoa + atp + hco3 <==> adp + h + malcoa + pi"]
[null,null,"ACACT1r","[c](2) accoa <==> aacoa + coa","<=>",{"$nulls":5},"<=>"]
[null,null,"CDAPPA_EC","[c](0.02) cdpdag1 + h2o --> cmp + (2) h + (0.02) pa_EC"]
[null,null,"DASYN_EC","[c]ctp + h + (0.02) pa_EC <==> (0.02) cdpdag1 + ppi",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"CLPNS_EC","[c](0.04) pg_EC <==> (0.02) clpn_EC + glyc"]
[null,null,"C140SN","[c]actACP + (17) h + (5) malACP + (12) nadph --> (5) ACP + (5) co2tot + h2o + myrsACP + (12) nadp",{"$nulls":4},"-->",null,"-->"]
[null,null,"C120SN","[c]actACP + (14) h + (4) malACP + (10) nadph --> (4) ACP + (4) co2tot + ddcaACP + h2o + (10) nadp"]
[null,null,"MACPD","[c]h + malACP + h2o --> acACP + co2tot",{"$nulls":4},"-->",null,"-->"]
[null,null,"KAS14","[c]acACP + h + malACP + h2o --> ACP + actACP + co2tot",{"$nulls":4},"-->",null,"-->"]
[null,null,"MCOATA","[c]ACP + malcoa <==> coa + malACP"]
[null,null,"C160SN","[c]actACP + (20) h + (6) malACP + (14) nadph --> (6) ACP + (6) co2tot + h2o + (14) nadp + palmACP",{"$nulls":4},"-->",null,"-->"]
[null,null,"KAS16","[c]ddcaACP + (2) h + malACP + nadph + h2o --> 3hmrsACP + ACP + co2tot + nadp"]
[null,null,"C181SN","[c]actACP + (22) h + (7) malACP + (15) nadph --> (7) ACP + (7) co2tot + h2o + (15) nadp + octeACP"]
[null,null,"C141SN","[c]actACP + (16) h + (5) malACP + (11) nadph --> (5) ACP + (5) co2tot + h2o + (11) nadp + tdeACP"]
[null,null,"KAS15","[c]accoa + h + malACP + h2o --> actACP + co2tot + coa",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"ACOATA","[c]ACP + accoa <==> acACP + coa"]
[null,null,"C161SN","[c]actACP + (19) h + (6) malACP + (13) nadph --> (6) ACP + (6) co2tot + h2o + hdeACP + (13) nadp"]
[null,null,"FAO2","[c]atp + (8) coa + (7) fad + (7) h2o + hdca + (7) nad --> (8) accoa + amp + (7) fadh2 + (7) h + (7) nadh + ppi"]
[null,null,"FAO1","[c]atp + (7) coa + (6) fad + (6) h2o + (6) nad + ttdca --> (7) accoa + amp + (6) fadh2 + (6) h + (6) nadh + ppi"]
[null,null,"FAO3","[c]atp + (9) coa + (8) fad + (8) h2o + (8) nad + ocdca --> (9) accoa + amp + (8) fadh2 + (8) h + (8) nadh + ppi"]
[null,null,"PGPP_EC","[c]h2o + (0.02) pgp_EC --> (0.02) pg_EC + pi"]
[null,null,"PGSA_EC","[c](0.02) cdpdag1 + glyc3p <==> cmp + h + (0.02) pgp_EC"]
[null,null,"PASYN_EC","[c]glyc3p + (0.14) hdeACP + (0.04) myrsACP + octeACP + (0.72) palmACP + (0.1) tdeACP --> (2) ACP + (0.02) pa_EC"]
[null,null,"PSD_EC","[c]h + (0.02) ps_EC + h2o --> co2tot + (0.02) pe_EC",{"$nulls":4},"-->",null,"-->"]
[null,null,"PSSA_EC","[c](0.02) cdpdag1 + ser-L <==> cmp + h + (0.02) ps_EC"]
[null,null,"AHC","[c]ahcys + h2o <==> adn + hcys-L"]
[null,null,"DHPTDC","[c]dhptd --> h2o + hmfurn"]
[null,null,"RHCCE","[c]rhcys --> dhptd + hcys-L"]
[null,null,"HSST","[c]hom-L + succoa --> coa + suchms"]
[null,null,"SHSL1","[c]cys-L + suchms --> cyst-L + h + succ"]
[null,null,"CYSTL","[c]cyst-L + h2o --> hcys-L + nh4 + pyr"]
[null,null,"METS","[c]5mthf + hcys-L --> met-L + thf"]
[null,null,"METAT","[c]atp + h2o + met-L --> amet + pi + ppi"]
[null,null,"AHCYSNS","[c]ahcys + h2o --> ade + rhcys"]
[null,null,"LGTHL","[c]gthrd + mthgxl --> lgt-S"]
[null,null,"GLYOX","[c]h2o + lgt-S --> gthrd + h + lac-D"]
[null,null,"MGSA","[c]dhap --> mthgxl + pi"]
[null,null,"UGLYCH","[c](2) h + (2) h2o + urdglyc --> co2tot + glx + (2) nh4"]
[null,null,"ALLTN","[c]alltn + h2o --> alltt + h"]
[null,null,"ALLTAH","[c]alltt + h2o --> urdglyc + urea"]
[null,null,"CYNTAH","[c]cynt + (3) h + hco3  + (2) h2o --> (2) co2tot + nh4"]
[null,null,"CMPN","[c]cmp + h2o --> csn + r5p"]
[null,null,"ADA","[c]adn + h + h2o --> ins + nh4","-->",{"$nulls":5},"-->"]
[null,null,"DADA","[c]dad-2 + h + h2o --> din + nh4"]
[null,null,"ADNK1","[c]adn + atp --> adp + amp + h","<=>",null,"-->",{"$nulls":3},"-->"]
[null,null,"ADK1","[c]amp + atp <==> (2) adp","<=>",{"$nulls":5},"<=>"]
[null,null,"DADK","[c]atp + damp <==> adp + dadp","<=>",{"$nulls":5},"<=>"]
[null,null,"ADK4","[c]amp + itp <==> adp + idp","<=>",{"$nulls":5},"<=>"]
[null,null,"ADK3","[c]amp + gtp <==> adp + gdp","<=>",{"$nulls":5},"<=>"]
[null,null,"AMPN","[c]amp + h2o --> ade + r5p","<=>",{"$nulls":5},"<=>"]
[null,null,"AP4AH","[c]ap4a + h2o --> (2) adp + (2) h"]
[null,null,"GP4GH","[c]gp4g + h2o --> (2) gdp + (2) h"]
[null,null,"AP5AH","[c]ap5a + h2o --> adp + atp + (2) h"]
[null,null,"ADPT","[c]ade + prpp --> amp + ppi","<=>",{"$nulls":5},"<=>"]
[null,null,"CYTD","[c]cytd + h + h2o --> nh4 + uri"]
[null,null,"DCYTD","[c]dcyt + h + h2o --> duri + nh4"]
[null,null,"CYTK2","[c]atp + dcmp <==> adp + dcdp"]
[null,null,"CYTK1","[c]atp + cmp <==> adp + cdp"]
[null,null,"UMPK","[c]atp + ump <==> adp + udp"]
[null,null,"CSND","[c]csn + h + h2o --> nh4 + ura"]
[null,null,"ADNCYC","[c]atp --> camp + ppi","<=>",{"$nulls":5},"<=>"]
[null,null,"DCTPD","[c]dctp + h + h2o --> dutp + nh4"]
[null,null,"TMDPP","[c]pi + thymd <==> 2dr1p + thym"]
[null,null,"DURIPP","[c]duri + pi <==> 2dr1p + ura"]
[null,null,"NTPTP1","[c]dgtp + h2o --> dgsn + pppi"]
[null,null,"NTPTP2","[c]gtp + h2o --> gsn + pppi",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"DUTPDP","[c]dutp + h2o --> dump + h + ppi"]
[null,null,"GK1","[c]atp + gmp <==> adp + gdp"]
[null,null,"DGK1","[c]atp + dgmp <==> adp + dgdp"]
[null,null,"XPPT","[c]prpp + xan --> ppi + xmp","<=>",{"$nulls":5},"<=>"]
[null,null,"HXPRT","[c]hxan + prpp --> imp + ppi","<=>",{"$nulls":5},"<=>"]
[null,null,"GUAPRT","[c]gua + prpp --> gmp + ppi"]
[null,null,"INSK","[c]atp + ins --> adp + h + imp","<=>",{"$nulls":5},"<=>"]
[null,null,"GSNK","[c]atp + gsn --> adp + gmp + h",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"NTPP3","[c]dctp + h2o --> dcmp + h + ppi"]
[null,null,"NTPP4","[c]ctp + h2o --> cmp + h + ppi"]
[null,null,"NTPP5","[c]datp + h2o --> damp + h + ppi","-->",{"$nulls":5},"-->"]
[null,null,"NTPP6","[c]atp + h2o --> amp + h + ppi","-->",{"$nulls":5},"-->"]
[null,null,"NTPP7","[c]dttp + h2o --> dtmp + h + ppi"]
[null,null,"NTPP8","[c]h2o + utp --> h + ppi + ump"]
[null,null,"NTPP1","[c]dgtp + h2o --> dgmp + h + ppi"]
[null,null,"NTPP2","[c]gtp + h2o --> gmp + h + ppi"]
[null,null,"NDPK1","[c]atp + gdp <==> adp + gtp","<=>",{"$nulls":5},"<=>"]
[null,null,"NDPK2","[c]atp + udp <==> adp + utp"]
[null,null,"NDPK3","[c]atp + cdp <==> adp + ctp"]
[null,null,"NDPK5","[c]atp + dgdp <==> adp + dgtp"]
[null,null,"NDPK6","[c]atp + dudp <==> adp + dutp"]
[null,null,"NDPK7","[c]atp + dcdp <==> adp + dctp"]
[null,null,"NDPK8","[c]atp + dadp <==> adp + datp","<=>",{"$nulls":5},"<=>"]
[null,null,"NDPK4","[c]atp + dtdp <==> adp + dttp"]
[null,null,"RNDR1","[c]adp + trdrd --> dadp + h2o + trdox","-->",{"$nulls":5},"-->"]
[null,null,"RNDR2","[c]gdp + trdrd --> dgdp + h2o + trdox"]
[null,null,"RNDR4","[c]trdrd + udp --> dudp + h2o + trdox"]
[null,null,"RNDR3","[c]cdp + trdrd --> dcdp + h2o + trdox"]
[null,null,"RNTR1","[c]atp + trdrd --> datp + h2o + trdox","-->",{"$nulls":5},"-->"]
[null,null,"RNTR2","[c]gtp + trdrd --> dgtp + h2o + trdox",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"RNTR3","[c]ctp + trdrd --> dctp + h2o + trdox"]
[null,null,"RNTR4","[c]trdrd + utp --> dutp + h2o + trdox"]
[null,null,"URIDK2r","[c]atp + dump <==> adp + dudp"]
[null,null,"DURIK1","[c]atp + duri --> adp + dump + h",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"TMDK1","[c]atp + thymd --> adp + dtmp + h",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"TMDS","[c]dump + mlthf --> dhf + dtmp"]
[null,null,"DTMPK","[c]atp + dtmp <==> adp + dtdp"]
[null,null,"URIK2","[c]gtp + uri --> gdp + h + ump",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"CYTDK2","[c]cytd + gtp --> cmp + gdp + h",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"PYNP2r","[c]pi + uri <==> r1p + ura"]
[null,null,"UPPRT","[c]prpp + ura --> ppi + ump"]
[null,null,"NTD1","[c]dump + h2o --> duri + pi"]
[null,null,"NTD5","[c]dtmp + h2o --> pi + thymd"]
[null,null,"NTD6","[c]damp + h2o --> dad-2 + pi","<=>",{"$nulls":5},"<=>"]
[null,null,"NTD8","[c]dgmp + h2o --> dgsn + pi"]
[null,null,"NTD3","[c]dcmp + h2o --> dcyt + pi"]
[null,null,"NTD4","[c]cmp + h2o --> cytd + pi"]
[null,null,"NTD7","[c]amp + h2o --> adn + pi","<=>",{"$nulls":5},"<=>"]
[null,null,"NTD9","[c]gmp + h2o --> gsn + pi"]
[null,null,"NTD11","[c]h2o + imp --> ins + pi","<=>",{"$nulls":5},"<=>"]
[null,null,"NTD10","[c]h2o + xmp --> pi + xtsn","<=>",{"$nulls":5},"<=>"]
[null,null,"NTD2","[c]h2o + ump --> pi + uri"]
[null,null,"PUNP6","[c]din + pi <==> 2dr1p + hxan"]
[null,null,"PUNP5","[c]ins + pi <==> hxan + r1p","<=>",{"$nulls":5},"<=>"]
[null,null,"PUNP2","[c]dad-2 + pi <==> 2dr1p + ade","<=>",{"$nulls":5},"<=>"]
[null,null,"PUNP4","[c]dgsn + pi <==> 2dr1p + gua"]
[null,null,"PUNP1","[c]adn + pi <==> ade + r1p","<=>",{"$nulls":5},"<=>"]
[null,null,"PUNP3","[c]gsn + pi <==> gua + r1p","<=>",{"$nulls":5},"<=>"]
[null,null,"PUNP7","[c]pi + xtsn <==> r1p + xan","<=>",{"$nulls":5},"<=>"]
[null,null,"GUAD","[c]gua + h + h2o --> nh4 + xan","-->",{"$nulls":5},"-->"]
[null,null,"ADD","[c]ade + h + h2o --> hxan + nh4","-->",{"$nulls":5},"-->"]
[null,null,"L-LACD2","[c]lac-L + q8 --> pyr + q8h2"]
[null,null,"L-LACD3","[c]lac-L + mqn8 --> mql8 + pyr"]
[null,null,"CRNBTCT","[c]bbtcoa + crn <==> crncoa + gbbtn"]
[null,null,"CRNCBCT","[c]crn + ctbtcoa <==> crncoa + ctbt"]
[null,null,"CRNCDH","[c]crncoa <==> ctbtcoa + h2o"]
[null,null,"CYTBD","(2) h[c] + (0.5) o2[c] + q8h2[c] --> (2) h[e] + h2o[c] + q8[c]","-->",{"$nulls":5},"-->"]
[null,null,"CYTBO3","(2.5) h[c] + (0.5) o2[c] + q8h2[c] --> (2.5) h[e] + h2o[c] + q8[c]","-->",{"$nulls":5},"-->"]
[null,null,"LDH_D2","[c]lac-D + q8 --> pyr + q8h2","<=>",{"$nulls":5},"<=>"]
[null,null,"DMSOR1","[c]dmso + mql8 --> dms + h2o + mqn8"]
[null,null,"DMSOR2","[c]2dmmql8 + dmso --> 2dmmq8 + dms + h2o"]
[null,null,"TMAOR1","[c]h + mql8 + tmao --> h2o + mqn8 + tma"]
[null,null,"TMAOR2","[c]2dmmql8 + h + tmao --> 2dmmq8 + h2o + tma"]
[null,null,"FDH2","for[c] + (3) h[c] + q8[c] + h2o[c]--> co2tot[c] + (2) h[e] + q8h2[c]","-->",{"$nulls":5},"-->"]
[null,null,"FDH3","for[c] + (3) h[c] + mqn8[c] + h2o[c] --> co2tot[c] + (2) h[e] + mql8[c]","-->",{"$nulls":5},"-->"]
[null,null,"GLCDe","glc-D[e] + h2o[e] + q8[c] --> glcn[e] + h[e] + q8h2[c]"]
[null,null,"G3PD7","[c]2dmmq8 + glyc3p --> 2dmmql8 + dhap","<=>",{"$nulls":5},"<=>"]
[null,null,"G3PD6","[c]glyc3p + mqn8 --> dhap + mql8","<=>",{"$nulls":5},"<=>"]
[null,null,"G3PD5","[c]glyc3p + q8 --> dhap + q8h2","<=>",{"$nulls":5},"<=>"]
[null,null,"HYD3","2dmmq8[c] + (2) h[c] + h2[c] --> 2dmmql8[c] + (2) h[e]","-->",{"$nulls":5},"-->"]
[null,null,"HYD1","(2) h[c] + h2[c] + q8[c] --> (2) h[e] + q8h2[c]","-->",{"$nulls":5},"-->"]
[null,null,"HYD2","(2) h[c] + h2[c] + mqn8[c] --> (2) h[e] + mql8[c]","-->",{"$nulls":5},"-->"]
[null,null,"NO3R1","(2) h[c] + no3[c] + q8h2[c] --> (2) h[e] + h2o[c] + no2[c] + q8[c]","-->",{"$nulls":5},"-->"]
[null,null,"NO3R2","(2) h[c] + mql8[c] + no3[c] --> (2) h[e] + h2o[c] + mqn8[c] + no2[c]","-->",{"$nulls":5},"-->"]
[null,null,"NADH5","[c]h + nadh + q8 --> nad + q8h2","-->",{"$nulls":5},"-->"]
[null,null,"NADH9","[c]2dmmq8 + h + nadh --> 2dmmql8 + nad","-->",{"$nulls":5},"-->"]
[null,null,"NADH10","[c]h + mqn8 + nadh --> mql8 + nad","-->",{"$nulls":5},"-->"]
[null,null,"NTRIR2x","[c](5) h + (3) nadh + no2 --> (2) h2o + (3) nad + nh4","-->",{"$nulls":5},"-->"]
[null,null,"NADH6","(4.5) h[c] + nadh[c] + q8[c] --> (3.5) h[e] + nad[c] + q8h2[c]","<=>",{"$nulls":5},"<=>"]
[null,null,"NADH7","(3) h[c] + mqn8[c] + nadh[c] --> (2) h[e] + mql8[c] + nad[c]","-->",{"$nulls":5},"-->"]
[null,null,"NADH8","2dmmq8[c] + (3.8) h[c] + nadh[c] --> 2dmmql8[c] + (2.8) h[e] + nad[c]","<=>",{"$nulls":5},"<=>"]
[null,null,"THD2","(2) h[e] + nadh[c] + nadp[c] --> (2) h[c] + nad[c] + nadph[c]","<=>",{"$nulls":5},"<=>"]
[null,null,"POX","[c](2) h2o + pyr + q8 --> ac + co2tot + q8h2","-->",{"$nulls":5},"-->"]
[null,null,"SUCD4","[c]fadh2 + q8 <==> fad + q8h2","<=>",{"$nulls":5},"<=>"]
[null,null,"TEST_NADTRHD","[c]nad + nadph --> nadh + nadp","<=>",{"$nulls":5},"<=>"]
[null,null,"TMAOR1e","h[e] + mql8[c] + tmao[e] --> h2o[e] + mqn8[c] + tma[e]"]
[null,null,"TMAOR2e","2dmmql8[c] + h[e] + tmao[e] --> 2dmmq8[c] + h2o[e] + tma[e]"]
[null,null,"DMSOR1e","dmso[e] + mql8[c] --> dms[e] + h2o[e] + mqn8[c]"]
[null,null,"DMSOR2e","2dmmql8[c] + dmso[e] --> 2dmmq8[c] + dms[e] + h2o[e]"]
[null,null,"TRDR","[c]h + nadph + trdox --> nadp + trdrd","<=>",{"$nulls":5},"<=>"]
[null,null,"PGL","[c]6pgl + h2o --> 6pgc + h","-->",{"$nulls":5},"-->"]
[null,null,"EDA","[c]2ddg6p --> g3p + pyr","<=>",{"$nulls":5},"<=>"]
[null,null,"EDD","[c]6pgc --> 2ddg6p + h2o","-->",{"$nulls":5},"-->"]
[null,null,"GND","[c]6pgc + nadp + h2o --> co2tot + nadph + ru5p-D","<=>",{"$nulls":5},"<=>"]
[null,null,"RPE","[c]ru5p-D <==> xu5p-D"]
[null,null,"RPI","[c]r5p <==> ru5p-D","<=>",{"$nulls":5},"<=>"]
[null,null,"TALA","[c]g3p + s7p <==> e4p + f6p","<=>",{"$nulls":5},"<=>"]
[null,null,"TKT1","[c]r5p + xu5p-D <==> g3p + s7p"]
[null,null,"TKT2","[c]e4p + xu5p-D <==> f6p + g3p"]
[null,null,"G6PDH2r","[c]g6p + nadp <==> 6pgl + h + nadph","<=>",{"$nulls":5},"<=>"]
[null,null,"GMPS2","[c]atp + gln-L + h2o + xmp --> amp + glu-L + gmp + (2) h + ppi"]
[null,null,"IMPD","[c]h2o + imp + nad --> h + nadh + xmp"]
[null,null,"GMPR","[c]gmp + (2) h + nadph --> imp + nadp + nh4"]
[null,null,"ADSS","[c]asp-L + gtp + imp --> dcamp + gdp + (2) h + pi",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"ADSL2r","[c]25aics <==> aicar + fum"]
[null,null,"ADSL1r","[c]dcamp <==> amp + fum"]
[null,null,"PRASCS","[c]5aizc + asp-L + atp <==> 25aics + adp + h + pi",{"$nulls":4},"-->",null,"-->"]
[null,null,"PRAGSr","[c]atp + gly + pram <==> adp + gar + h + pi",{"$nulls":4},"-->",null,"-->"]
[null,null,"AIRC3","[c]5aizc <==> 5caiz"]
[null,null,"GLUPRT","[c]gln-L + h2o + prpp --> glu-L + ppi + pram"]
[null,null,"AICART","[c]10fthf + aicar <==> fprica + thf"]
[null,null,"IMPC","[c]h2o + imp <==> fprica"]
[null,null,"AIRC2","[c]air + atp + hco3 --> 5caiz + adp + h + pi",{"$nulls":4},"-->",null,"-->"]
[null,null,"PRFGS","[c]atp + fgam + gln-L + h2o --> adp + fpram + glu-L + h + pi",{"$nulls":4},"-->",null,"-->"]
[null,null,"PRAIS","[c]atp + fpram --> adp + air + (2) h + pi",{"$nulls":4},"-->",null,"-->"]
[null,null,"GARFT","[c]10fthf + gar <==> fgam + h + thf"]
[null,null,"GART","[c]atp + for + gar --> adp + fgam + h + pi"]
[null,null,"ASPCT","[c]asp-L + cbp --> cbasp + h + pi"]
[null,null,"DHORTS","[c]dhor-S + h2o <==> cbasp + h"]
[null,null,"DHORD2","[c]dhor-S + q8 --> orot + q8h2"]
[null,null,"DHORD5","[c]dhor-S + mqn8 --> mql8 + orot"]
[null,null,"ORPT","[c]orot5p + ppi <==> orot + prpp"]
[null,null,"OMPDC","[c]h + orot5p + h2o --> co2tot + ump",{"$nulls":4},"-->",null,"-->"]
[null,null,"CTPS2","[c]atp + gln-L + h2o + utp --> adp + ctp + glu-L + (2) h + pi",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"CBMK","[c]atp + co2tot + nh4 --> adp + cbp + (2) h + h2o","<=>",{"$nulls":5},"<=>"]
[null,null,"AMANAPE","[c]acmanap --> acgam6p"]
[null,null,"AMANK","[c]acmana + atp --> acmanap + adp + h"]
[null,null,"ALLTNt2r","alltn[e] + h[e] <==> alltn[c] + h[c]"]
[null,null,"ARGORNt7","arg-L[e] + orn[c] <==> arg-L[c] + orn[e]"]
[null,null,"ACACt2","acac[e] + h[e] <==> acac[c] + h[c]"]
[null,null,"BUTt2r","but[e] + h[e] <==> but[c] + h[c]"]
[null,null,"CYNTt2","cynt[e] + h[e] --> cynt[c] + h[c]"]
[null,null,"GALCTt2r","galct-D[e] + h[e] <==> galct-D[c] + h[c]"]
[null,null,"GLCRt2r","glcr[e] + h[e] <==> glcr[c] + h[c]"]
[null,null,"PPPNt2r","h[e] + pppn[e] <==> h[c] + pppn[c]"]
[null,null,"HPPPNt2r","3hpppn[e] + h[e] <==> 3hpppn[c] + h[c]"]
[null,null,"HCINNMt2r","3hcinnm[e] + h[e] <==> 3hcinnm[c] + h[c]"]
[null,null,"GLUABUTt7","4abut[c] + glu-L[e] <==> 4abut[e] + glu-L[c]"]
[null,null,"ALAt2r","ala-L[e] + h[e] <==> ala-L[c] + h[c]"]
[null,null,"URAt2r","h[e] + ura[e] <==> h[c] + ura[c]"]
[null,null,"GLYBt2r","glyb[e] + h[e] <==> glyb[c] + h[c]"]
[null,null,"CHLabc","atp[c] + chol[e] + h2o[c] --> adp[c] + chol[c] + h[c] + pi[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"GLYBabc","atp[c] + glyb[e] + h2o[c] --> adp[c] + glyb[c] + h[c] + pi[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"TARTRt7","succ[c] + tartr-L[e] <==> succ[e] + tartr-L[c]"]
[null,null,"SUCCabc","atp[c] + h2o[c] + succ[e] --> adp[c] + h[c] + pi[c] + succ[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"GUAt2","gua[e] + h[e] --> gua[c] + h[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"XANt2","h[e] + xan[e] --> h[c] + xan[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"ACKr","[c]ac + atp <==> actp + adp","<=>",{"$nulls":5},"<=>"]
[null,null,"ACS","[c]ac + atp + coa --> accoa + amp + ppi","<=>",{"$nulls":5},"<=>"]
[null,null,"ADHEr","[c]accoa + (2) h + (2) nadh <==> coa + etoh + (2) nad","<=>",{"$nulls":5},"<=>"]
[null,null,"LDH_D","[c]lac-D + nad <==> h + nadh + pyr","<=>",{"$nulls":5},"<=>"]
[null,null,"FHL","[c]for + h + h2o --> co2tot + h2","<=>",{"$nulls":5},"<=>"]
[null,null,"PTAr","[c]accoa + pi <==> actp + coa","<=>",{"$nulls":5},"<=>"]
[null,null,"PFL","[c]coa + pyr --> accoa + for","<=>",{"$nulls":5},"<=>"]
[null,null,"SDPTA","[c]akg + sl26da <==> glu-L + sl2a6o"]
[null,null,"ASAD","[c]aspsa + nadp + pi <==> 4pasp + h + nadph"]
[null,null,"DHDPS","[c]aspsa + pyr --> 23dhdp + h + (2) h2o"]
[null,null,"DHDPRy","[c]23dhdp + h + nadph --> nadp + thdp"]
[null,null,"THDPS","[c]h2o + succoa + thdp --> coa + sl2a6o"]
[null,null,"SDPDS","[c]h2o + sl26da --> 26dap-LL + succ"]
[null,null,"DAPE","[c]26dap-LL <==> 26dap-M"]
[null,null,"LYSDC","[c]h + lys-L + h2o --> 15dap + co2tot"]
[null,null,"THRAr","[c]thr-L <==> acald + gly","<=>",{"$nulls":5},"<=>"]
[null,null,"DAPDC","[c]26dap-M + h + h2o --> co2tot + lys-L"]
[null,null,"HSDy","[c]hom-L + nadp <==> aspsa + h + nadph"]
[null,null,"ASPK","[c]asp-L + atp <==> 4pasp + adp",{"$nulls":4},"-->",null,"-->"]
[null,null,"HSK","[c]atp + hom-L --> adp + h + phom",{"$nulls":4},"-->",null,"-->"]
[null,null,"THRS","[c]h2o + phom --> pi + thr-L"]
[null,null,"12PPDt","12ppd-S[e] <==> 12ppd-S[c]"]
[null,null,"NMNt7","h2o[c] + nmn[e] --> h[c] + ncam[c] + r5p[c]"]
[null,null,"ACALDt","acald[e] <==> acald[c]"]
[null,null,"GUAt","gua[e] <==> gua[c]"]
[null,null,"HYXNt","hxan[e] <==> hxan[c]"]
[null,null,"XANt","xan[e] <==> xan[c]"]
[null,null,"NACUP","nac[e] --> nac[c]"]
[null,null,"ASNabc","asn-L[e] + atp[c] + h2o[c] --> adp[c] + asn-L[c] + h[c] + pi[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"ASNt2r","asn-L[e] + h[e] <==> asn-L[c] + h[c]"]
[null,null,"DAPabc","26dap-M[e] + atp[c] + h2o[c] --> 26dap-M[c] + adp[c] + h[c] + pi[c]"]
[null,null,"CYSabc","atp[c] + cys-L[e] + h2o[c] --> adp[c] + cys-L[c] + h[c] + pi[c]"]
[null,null,"ACt2r","ac[e] + h[e] <==> ac[c] + h[c]"]
[null,null,"ETOHt2r","etoh[e] + h[e] <==> etoh[c] + h[c]"]
[null,null,"PYRt2r","h[e] + pyr[e] <==> h[c] + pyr[c]"]
[null,null,"O2t","o2[e] <==> o2[c]","<=>",{"$nulls":5},"<=>"]
[null,null,"CO2t","co2tot[e] + h2o[c] <==> co2tot[c] + h2o[e]","<=>",{"$nulls":5},"<=>"]
[null,null,"H2Ot","h2o[e] <==> h2o[c]"]
[null,null,"DHAt","dha[e] <==> dha[c]"]
[null,null,"NH3t","nh4[e] <==> nh4[c]","<=>",{"$nulls":5},"<=>"]
[null,null,"ARBt2r","arab-L[e] + h[e] <==> arab-L[c] + h[c]"]
[null,null,"ARBabc","arab-L[e] + atp[c] + h2o[c] --> adp[c] + arab-L[c] + h[c] + pi[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"HISt2r","h[e] + his-L[e] <==> h[c] + his-L[c]"]
[null,null,"PHEt2r","h[e] + phe-L[e] <==> h[c] + phe-L[c]"]
[null,null,"LEUt2r","h[e] + leu-L[e] <==> h[c] + leu-L[c]"]
[null,null,"VALt2r","h[e] + val-L[e] <==> h[c] + val-L[c]"]
[null,null,"ILEt2r","h[e] + ile-L[e] <==> h[c] + ile-L[c]"]
[null,null,"CBL1abc","atp[c] + cbl1[e] + h2o[c] --> adp[c] + cbl1[c] + h[c] + pi[c]"]
[null,null,"CADVt","15dap[c] + h[e] + lys-L[e] --> 15dap[e] + h[c] + lys-L[c]"]
[null,null,"CRNt7","crn[e] + gbbtn[c] --> crn[c] + gbbtn[e]"]
[null,null,"NAt3_1","h[e] + na1[c] <==> h[c] + na1[e]"]
[null,null,"CITt7","cit[e] + succ[c] --> cit[c] + succ[e]"]
[null,null,"CSNt2","csn[e] + h[e] --> csn[c] + h[c]"]
[null,null,"MALTpts","malt[e] + pep[c] --> malt6p[c] + pyr[c]"]
[null,null,"ACGApts","acgam[e] + pep[c] --> acgam6p[c] + pyr[c]"]
[null,null,"DALAt2r","ala-D[e] + h[e] <==> ala-D[c] + h[c]"]
[null,null,"DSERt2r","h[e] + ser-D[e] <==> h[c] + ser-D[c]"]
[null,null,"GLYt2r","gly[e] + h[e] <==> gly[c] + h[c]"]
[null,null,"SULabc","atp[c] + h2o[c] + so4[e] --> adp[c] + h[c] + pi[c] + so4[c]"]
[null,null,"ASPt2_2","asp-L[e] + (2) h[e] --> asp-L[c] + (2) h[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"FUMt2_2","fum[e] + (2) h[e] --> fum[c] + (2) h[c]"]
[null,null,"MALt2_2","(2) h[e] + mal-L[e] --> (2) h[c] + mal-L[c]"]
[null,null,"SUCCt2_2","(2) h[e] + succ[e] --> (2) h[c] + succ[c]"]
[null,null,"ASPt2_3","asp-L[e] + (3) h[e] --> asp-L[c] + (3) h[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"MALt2_3","(3) h[e] + mal-L[e] --> (3) h[c] + mal-L[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"SUCCt2_3","(3) h[e] + succ[e] --> (3) h[c] + succ[c]"]
[null,null,"SUCCt2b","h[c] + succ[c] --> h[e] + succ[e]"]
[null,null,"FUMt2_3","fum[e] + (3) h[e] --> fum[c] + (3) h[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"SUCFUMt","fum[e] + succ[c] <==> fum[c] + succ[e]"]
[null,null,"GALCTNt2r","galctn-D[e] + h[e] <==> galctn-D[c] + h[c]"]
[null,null,"GALURt2r","galur[e] + h[e] <==> galur[c] + h[c]"]
[null,null,"GLCURt2r","glcur[e] + h[e] <==> glcur[c] + h[c]"]
[null,null,"OCDCAt2","h[e] + ocdca[e] --> h[c] + ocdca[c]"]
[null,null,"HDCAt2","h[e] + hdca[e] --> h[c] + hdca[c]"]
[null,null,"TTDCAt2","h[e] + ttdca[e] --> h[c] + ttdca[c]"]
[null,null,"FE2abc","atp[c] + fe2[e] + h2o[c] --> adp[c] + fe2[c] + h[c] + pi[c]"]
[null,null,"FORt","for[e] <==> for[c]"]
[null,null,"FUCt","fuc-L[e] + h[e] <==> fuc-L[c] + h[c]"]
[null,null,"ABUTt2","4abut[e] + h[e] --> 4abut[c] + h[c]"]
[null,null,"GALt2","gal[e] + h[e] --> gal[c] + h[c]"]
[null,null,"GLCt2","glc-D[e] + h[e] --> glc-D[c] + h[c]"]
[null,null,"GALTpts","galt[e] + pep[c] --> galt1p[c] + pyr[c]"]
[null,null,"GLNabc","atp[c] + gln-L[e] + h2o[c] --> adp[c] + gln-L[c] + h[c] + pi[c]"]
[null,null,"GLYCt","glyc[c] <==> glyc[e]"]
[null,null,"GLYALDt","glyald[e] <==> glyald[c]"]
[null,null,"UREAt","urea[e] <==> urea[c]"]
[null,null,"GLYC3Pt6","glyc3p[e] + pi[c] --> glyc3p[c] + pi[e]"]
[null,null,"ASPabc","asp-L[e] + atp[c] + h2o[c] --> adp[c] + asp-L[c] + h[c] + pi[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"GLUabc","atp[c] + glu-L[e] + h2o[c] --> adp[c] + glu-L[c] + h[c] + pi[c]",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"ASPt2","asp-L[e] + h[e] --> asp-L[c] + h[c]"]
[null,null,"GLUt2r","glu-L[e] + h[e] <==> glu-L[c] + h[c]"]
[null,null,"GLUt4","glu-L[e] + na1[e] --> glu-L[c] + na1[c]"]
[null,null,"ORNabc","atp[c] + h2o[c] + orn[e] --> adp[c] + h[c] + orn[c] + pi[c]",{"$nulls":4},"-->",null,"-->"]
[null,null,"ARGabc","arg-L[e] + atp[c] + h2o[c] --> adp[c] + arg-L[c] + h[c] + pi[c]"]
[null,null,"HISabc","atp[c] + h2o[c] + his-L[e] --> adp[c] + h[c] + his-L[c] + pi[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"LYSabc","atp[c] + h2o[c] + lys-L[e] --> adp[c] + h[c] + lys-L[c] + pi[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"IDONt2r","h[e] + idon-L[e] <==> h[c] + idon-L[c]"]
[null,null,"GLCNt2r","glcn[e] + h[e] <==> glcn[c] + h[c]"]
[null,null,"DDGLCNt2r","2ddglcn[e] + h[e] <==> 2ddglcn[c] + h[c]"]
[null,null,"Kabc","atp[c] + h2o[c] + k[e] --> adp[c] + h[c] + k[c] + pi[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"AKGt2r","akg[e] + h[e] <==> akg[c] + h[c]"]
[null,null,"LCTSt","h[e] + lcts[e] <==> h[c] + lcts[c]"]
[null,null,"ILEabc","atp[c] + h2o[c] + ile-L[e] --> adp[c] + h[c] + ile-L[c] + pi[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"THRabc","atp[c] + h2o[c] + thr-L[e] --> adp[c] + h[c] + pi[c] + thr-L[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"ALAabc","ala-L[e] + atp[c] + h2o[c] --> adp[c] + ala-L[c] + h[c] + pi[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"VALabc","atp[c] + h2o[c] + val-L[e] --> adp[c] + h[c] + pi[c] + val-L[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"LEUabc","atp[c] + h2o[c] + leu-L[e] --> adp[c] + h[c] + leu-L[c] + pi[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"D-LACt2","h[e] + lac-D[e] <==> h[c] + lac-D[c]"]
[null,null,"GLYCLTt2r","glyclt[e] + h[e] <==> glyclt[c] + h[c]"]
[null,null,"L-LACt2r","h[e] + lac-L[e] <==> h[c] + lac-L[c]"]
[null,null,"LYSt2r","h[e] + lys-L[e] <==> h[c] + lys-L[c]"]
[null,null,"MALTPTabc","atp[c] + h2o[c] + maltpt[e] --> adp[c] + h[c] + maltpt[c] + pi[c]"]
[null,null,"MALTabc","atp[c] + h2o[c] + malt[e] --> adp[c] + h[c] + malt[c] + pi[c]"]
[null,null,"MALTTTRabc","atp[c] + h2o[c] + maltttr[e] --> adp[c] + h[c] + maltttr[c] + pi[c]"]
[null,null,"MALTHXabc","atp[c] + h2o[c] + malthx[e] --> adp[c] + h[c] + malthx[c] + pi[c]"]
[null,null,"MALTTRabc","atp[c] + h2o[c] + malttr[e] --> adp[c] + h[c] + malttr[c] + pi[c]"]
[null,null,"FRUpts2","fru[e] + pep[c] --> f6p[c] + pyr[c]"]
[null,null,"MANpts","man[e] + pep[c] --> man6p[c] + pyr[c]"]
[null,null,"GAMpts","gam[e] + pep[c] --> gam6p[c] + pyr[c]"]
[null,null,"MELIBt2","h[e] + melib[e] --> h[c] + melib[c]"]
[null,null,"METabc","atp[c] + h2o[c] + met-L[e] --> adp[c] + h[c] + met-L[c] + pi[c]"]
[null,null,"METDabc","atp[c] + h2o[c] + met-D[e] --> adp[c] + h[c] + met-D[c] + pi[c]"]
[null,null,"GALabc","atp[c] + gal[e] + h2o[c] --> adp[c] + gal[c] + h[c] + pi[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"INDOLEt2r","h[e] + indole[e] <==> h[c] + indole[c]"]
[null,null,"ACNAMt2","acnam[e] + h[e] --> acnam[c] + h[c]"]
[null,null,"NO3t7","no2[c] + no3[e] --> no2[e] + no3[c]"]
[null,null,"NO2t2r","h[e] + no2[e] <==> h[c] + no2[c]"]
[null,null,"NAt3_2","(2) h[e] + na1[c] --> (2) h[c] + na1[e]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"NAt3_1.5","(3) h[e] + (2) na1[c] --> (3) h[c] + (2) na1[e]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"GSNt2","gsn[e] + h[e] --> gsn[c] + h[c]"]
[null,null,"DGSNt2","dgsn[e] + h[e] --> dgsn[c] + h[c]"]
[null,null,"DINSt2","din[e] + h[e] --> din[c] + h[c]"]
[null,null,"DCYTt2","dcyt[e] + h[e] --> dcyt[c] + h[c]"]
[null,null,"DURIt2","duri[e] + h[e] --> duri[c] + h[c]"]
[null,null,"DADNt2","dad-2[e] + h[e] --> dad-2[c] + h[c]"]
[null,null,"PNTOt4","na1[e] + pnto-R[e] --> na1[c] + pnto-R[c]"]
[null,null,"PIt2r","h[e] + pi[e] <==> h[c] + pi[c]"]
[null,null,"NMNP","nmn[e] --> nmn[c]"]
[null,null,"PTRCabc","atp[c] + h2o[c] + ptrc[e] --> adp[c] + h[c] + pi[c] + ptrc[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"SPMDabc","atp[c] + h2o[c] + spmd[e] --> adp[c] + h[c] + pi[c] + spmd[c]"]
[null,null,"PTRCORNt7","orn[c] + ptrc[e] <==> orn[e] + ptrc[c]"]
[null,null,"PTRCt2r","h[e] + ptrc[e] <==> h[c] + ptrc[c]"]
[null,null,"PROt2r","h[e] + pro-L[e] <==> h[c] + pro-L[c]"]
[null,null,"PROabc","atp[c] + h2o[c] + pro-L[e] --> adp[c] + h[c] + pi[c] + pro-L[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"PIabc","atp[c] + h2o[c] + pi[e] --> adp[c] + h[c] + (2) pi[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"ACMANApts","acmana[e] + pep[c] --> acmanap[c] + pyr[c]"]
[null,null,"MNLpts","mnl[e] + pep[c] --> mnl1p[c] + pyr[c]"]
[null,null,"SUCpts","pep[c] + sucr[e] --> pyr[c] + suc6p[c]"]
[null,null,"GLCpts","glc-D[e] + pep[c] --> g6p[c] + pyr[c]"]
[null,null,"FRUpts","fru[e] + pep[c] --> f1p[c] + pyr[c]"]
[null,null,"TREpts","pep[c] + tre[e] --> pyr[c] + tre6p[c]"]
[null,null,"PROt4","na1[e] + pro-L[e] --> na1[c] + pro-L[c]"]
[null,null,"RMNt","h[e] + rmn[e] --> h[c] + rmn[c]"]
[null,null,"TSULabc","atp[c] + h2o[c] + tsul[e] --> adp[c] + h[c] + pi[c] + tsul[c]"]
[null,null,"SERt2r","h[e] + ser-L[e] <==> h[c] + ser-L[c]"]
[null,null,"THMabc","atp[c] + h2o[c] + thm[e] --> adp[c] + h[c] + pi[c] + thm[c]"]
[null,null,"SBTpts","pep[c] + sbt-D[e] --> pyr[c] + sbt6p[c]"]
[null,null,"SERt4","na1[e] + ser-L[e] --> na1[c] + ser-L[c]"]
[null,null,"THRt4","na1[e] + thr-L[e] --> na1[c] + thr-L[c]"]
[null,null,"TAURabc","atp[c] + h2o[c] + taur[e] --> adp[c] + h[c] + pi[c] + taur[c]"]
[null,null,"THRt2r","h[e] + thr-L[e] <==> h[c] + thr-L[c]"]
[null,null,"TRPt2r","h[e] + trp-L[e] <==> h[c] + trp-L[c]"]
[null,null,"Kt2r","h[e] + k[e] <==> h[c] + k[c]"]
[null,null,"TYRt2r","h[e] + tyr-L[e] <==> h[c] + tyr-L[c]"]
[null,null,"GLYC3Pabc","atp[c] + glyc3p[e] + h2o[c] --> adp[c] + glyc3p[c] + h[c] + pi[c]",{"$nulls":3},"-->",null,null,"-->"]
[null,null,"MAN6Pt6_2","man6p[e] + (2) pi[c] --> man6p[c] + (2) pi[e]"]
[null,null,"G6Pt6_2","g6p[e] + (2) pi[c] --> g6p[c] + (2) pi[e]"]
[null,null,"FUCPt6_2","fuc1p-L[e] + (2) pi[c] --> fuc1p-L[c] + (2) pi[e]"]
[null,null,"XTSNt2r","h[e] + xtsn[e] <==> h[c] + xtsn[c]"]
[null,null,"INSt2r","h[e] + ins[e] <==> h[c] + ins[c]"]
[null,null,"ADNt2r","adn[e] + h[e] <==> adn[c] + h[c]"]
[null,null,"CYTDt2r","cytd[e] + h[e] <==> cytd[c] + h[c]"]
[null,null,"THMDt2r","h[e] + thymd[e] <==> h[c] + thymd[c]"]
[null,null,"URIt2r","h[e] + uri[e] <==> h[c] + uri[c]"]
[null,null,"XYLt2","h[e] + xyl-D[e] --> h[c] + xyl-D[c]"]
[null,null,"XYLabc","atp[c] + h2o[c] + xyl-D[e] --> adp[c] + h[c] + pi[c] + xyl-D[c]",null,null,"-->",{"$nulls":3},"-->"]
[null,null,"CHLt2r","chol[e] + h[e] <==> chol[c] + h[c]"]
[null,null,"ADEt2r","ade[e] + h[e] <==> ade[c] + h[c]"]
[null,null,"RIBabc","atp[c] + h2o[c] + rib-D[e] --> adp[c] + h[c] + pi[c] + rib-D[c]"]
[null,null,"PSCVT","[c]pep + skm5p <==> 3psme + pi"]
[null,null,"DHQS","[c]2dda7p --> 3dhq + pi","-->",{"$nulls":5},"-->"]
[null,null,"CHORS","[c]3psme --> chor + pi"]
[null,null,"DHQD","[c]3dhq <==> 3dhsk + h2o","<=>",{"$nulls":5},"<=>"]
[null,null,"SHK3Dr","[c]3dhsk + h + nadph <==> nadp + skm","<=>",{"$nulls":5},"<=>"]
[null,null,"DDPA","[c]e4p + h2o + pep --> 2dda7p + pi","<=>",{"$nulls":5},"<=>"]
[null,null,"SHKK","[c]atp + skm --> adp + h + skm5p"]
[null,null,"PPNDH","[c]h + pphn --> co2tot + phpyr"]
[null,null,"CHORM","[c]chor --> pphn"]
[null,null,"TRPAS2","[c]h2o + trp-L <==> indole + nh4 + pyr","<=>",{"$nulls":5},"<=>"]
[null,null,"TRPS2","[c]indole + ser-L --> h2o + trp-L","-->",{"$nulls":5},"-->"]
[null,null,"TRPS3","[c]3ig3p --> g3p + indole"]
[null,null,"TRPS1","[c]3ig3p + ser-L --> g3p + h2o + trp-L"]
[null,null,"PRAIi","[c]pran --> 2cpr5p"]
[null,null,"IGPS","[c]2cpr5p + h --> 3ig3p + co2tot"]
[null,null,"ANS","[c]chor + gln-L --> anth + glu-L + h + pyr"]
[null,null,"ANPRT","[c]anth + prpp --> ppi + pran"]
[null,null,"PPND","[c]nad + pphn + h2o --> 34hpp + co2tot + nadh"]
[null,null,"TYRTA","[c]akg + tyr-L <==> 34hpp + glu-L"]
[null,null,"PHETA1","[c]akg + phe-L <==> glu-L + phpyr"]
[null,null,"BETALDHx","[c]betald + h2o + nad --> glyb + (2) h + nadh"]
[null,null,"BETALDHy","[c]betald + h2o + nadp --> glyb + (2) h + nadph"]
[null,null,"HCO3E","[c]co2tot <==> h + hco3"]
[null,null,"CYANST","[c]cyan + tsul --> h + so3 + tcynt"]
[null,null,"CAT","[c](2) h2o2 --> (2) h2o + o2","-->",{"$nulls":5},"-->"]
[null,null,"SELNPS","[c]atp + h2o + seln --> amp + pi + selnp"]
[null,null,"SPODM","[c](2) h + (2) o2- --> h2o2 + o2"]
[null,null,"ACONMT","[c]acon-T + amet --> aconm + ahcys"]
[null,null,"THRD_L","[c]thr-L --> 2obut + nh4"]
[null,null,"ACHBS","[c]2obut + h + pyr + h2o --> 2ahbut + co2tot"]
[null,null,"ACLS","[c]h + (2) pyr + h2o --> alac-S + co2tot"]
[null,null,"KARA2i","[c]2ahbut + h + nadph --> 23dhmp + nadp"]
[null,null,"KARA1i","[c]alac-S + h + nadph --> 23dhmb + nadp"]
[null,null,"DHAD2","[c]23dhmp --> 3mop + h2o"]
[null,null,"DHAD1","[c]23dhmb --> 3mob + h2o"]
[null,null,"ILETA","[c]akg + ile-L <==> 3mop + glu-L"]
[null,null,"VALTA","[c]akg + val-L <==> 3mob + glu-L"]
[null,null,"LEUTAi","[c]4mop + glu-L --> akg + leu-L","<=>",{"$nulls":5},"<=>"]
[null,null,"IPPS","[c]3mob + accoa + h2o --> 3c3hmp + coa + h"]
[null,null,"IPMD","[c]3c2hmp + nad --> 3c4mop + h + nadh"]
[null,null,"OMCDC","[c]3c4mop + h + h2o --> 4mop + co2tot"]
[null,null,"IPPMIa","[c]3c2hmp <==> 2ippm + h2o"]
[null,null,"IPPMIb","[c]2ippm + h2o <==> 3c3hmp"]
[]
[null,null,"number of assignments",null,43,null,42,21,24,null,130]

{"sheet":"electron acceptor assignments ","index":1,"n_rows":927,"n_cols":14,"rows_kept":927,"merged":[[3,5,4,5],[3,7,4,7],[3,9,3,11]],"flags":["formulas_cached_only"]}
[]
[]
[]
[{"$nulls":5},"consideration of final electron acceptors",null,"thermodynamic facts",null,"topology and thermodynamically heuristic rules",{"$nulls":3},"summarized"]
[{"$nulls":3},"reaction","reaction equation with original reaction directions",{"$nulls":4},"pair cycles","remaining energy producing cycles","bypasses"]
[{"$nulls":3},"ALATA_L","[c]akg + ala-L <==> glu-L + pyr",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"ALAR","[c]ala-L <==> ala-D"]
[{"$nulls":3},"ASNN","[c]asn-L + h2o --> asp-L + nh4",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"ASNS2","[c]asp-L + atp + nh4 --> amp + asn-L + h + ppi",null,null,0,null,1,{"$nulls":3},1]
[{"$nulls":3},"ASNS1","[c]asp-L + atp + gln-L + h2o --> amp + asn-L + glu-L + h + ppi",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"ASPT","[c]asp-L --> fum + nh4",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"ASPTA","[c]akg + asp-L <==> glu-L + oaa",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"VPAMT","[c]3mob + ala-L --> pyr + val-L"]
[{"$nulls":3},"DAAD","[c]ala-D + fad + h2o --> fadh2 + nh4 + pyr"]
[{"$nulls":3},"FFSD","[c]h2o + suc6p --> fru + g6p"]
[{"$nulls":3},"A5PISO","[c]ru5p-D <==> ara5p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"MME","[c]mmcoa-R <==> mmcoa-S",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"MICITD","[c]2mcacn + h2o --> micit"]
[{"$nulls":3},"ALCD19","[c]glyald + h + nadh <==> glyc + nad",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"TGBPA","[c]tagdp-D <==> dhap + g3p"]
[{"$nulls":3},"LCAD","[c]h2o + lald-L + nad <==> (2) h + lac-L + nadh"]
[{"$nulls":3},"ALDD2x","[c]acald + h2o + nad --> ac + (2) h + nadh",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"ARAI","[c]arab-L <==> rbl-L",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"RBK_L1","[c]atp + rbl-L --> adp + h + ru5p-L",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"RBP4E","[c]ru5p-L <==> xu5p-D"]
[{"$nulls":3},"ACACCT","[c]acac + accoa --> aacoa + ac",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"BUTCT","[c]accoa + but --> ac + btcoa"]
[{"$nulls":3},"AB6PGH","[c]arbt6p + h2o --> g6p + hqn"]
[{"$nulls":3},"PMANM","[c]man1p <==> man6p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PPM2","[c]2dr1p <==> 2dr5p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PPM","[c]r1p <==> r5p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"DRPA","[c]2dr5p --> acald + g3p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GALCTND","[c]galctn-D --> 2dh3dgal + h2o"]
[{"$nulls":3},"DDPGALA","[c]2dh3dgal6p <==> g3p + pyr"]
[{"$nulls":3},"DDGALK","[c]2dh3dgal + atp --> 2dh3dgal6p + adp + h"]
[{"$nulls":3},"DHAPT","[c]dha + pep --> dhap + pyr",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"FAO4","[c]btcoa + fad + h2o + nad --> aacoa + fadh2 + h + nadh"]
[{"$nulls":3},"ALDD19x","[c]h2o + nad + pacald --> (2) h + nadh + pac"]
[{"$nulls":3},"FRUK","[c]atp + f1p --> adp + fdp + h",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"FCLPA","[c]fc1p <==> dhap + lald-L"]
[{"$nulls":3},"FCI","[c]fuc-L <==> fcl-L"]
[{"$nulls":3},"FCLK","[c]atp + fcl-L --> adp + fc1p + h"]
[{"$nulls":3},"LCAR","[c]h + lald-L + nadh <==> 12ppd-S + nad"]
[{"$nulls":3},"UDPG4E","[c]udpg <==> udpgal"]
[{"$nulls":3},"GALKr","[c]atp + gal <==> adp + gal1p + h",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"UGLT","[c]gal1p + udpg <==> g1p + udpgal"]
[{"$nulls":3},"GALU","[c]g1p + h + utp <==> ppi + udpg",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"GALCTD","[c]galct-D --> 5dh4dglc + h2o"]
[{"$nulls":3},"GLTPD","[c]galt1p + nad <==> h + nadh + tag6p-D"]
[{"$nulls":3},"GLYCTO2","[c]glyclt + q8 --> glx + q8h2",1,null,0,{"$nulls":5},1]
[{"$nulls":3},"GLYCTO3","[c]glyclt + mqn8 --> glx + mql8",1,null,0,{"$nulls":5},1]
[{"$nulls":3},"GLYCTO4","[c]2dmmq8 + glyclt --> 2dmmql8 + glx",1,null,0,{"$nulls":5},1]
[{"$nulls":3},"GLYCDx","[c]glyc + nad --> dha + h + nadh",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GLYK","[c]atp + glyc --> adp + glyc3p + h",null,null,0,null,null,1,null,null,0]
[{"$nulls":3},"PGLYCP","[c]2pglyc + h2o --> glyclt + pi"]
[{"$nulls":3},"G3PD2","[c]glyc3p + nadp <==> dhap + h + nadph",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GLCRAL","[c]5dh4dglc --> 2h3oppan + pyr"]
[{"$nulls":3},"DHPPD","[c]cechddd + nad --> dhpppn + h + nadh"]
[{"$nulls":3},"DHCIND","[c]cenchddd + nad --> dhcinnm + h + nadh"]
[{"$nulls":3},"PPPNDO","[c]h + nadh + o2 + pppn --> cechddd + nad"]
[{"$nulls":3},"CINNDO","[c]cinnm + h + nadh + o2 --> cenchddd + nad"]
[{"$nulls":3},"HPYRI","[c]hpyr <==> 2h3oppan"]
[{"$nulls":3},"IDOND","[c]5dglcn + h + nadh <==> idon-L + nad"]
[{"$nulls":3},"IDOND2","[c]5dglcn + h + nadph --> idon-L + nadp"]
[{"$nulls":3},"GNK","[c]atp + glcn --> 6pgc + adp + h"]
[{"$nulls":3},"5DGLCNR","[c]5dglcn + h + nadph <==> glcn + nadp"]
[{"$nulls":3},"DDGLK","[c]2ddglcn + atp --> 2ddg6p + adp + h"]
[{"$nulls":3},"LACZ","[c]h2o + lcts --> gal + glc-D",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"MLTP1","[c]maltpt + pi <==> g1p + maltttr"]
[{"$nulls":3},"MLTP2","[c]malthx + pi <==> g1p + maltpt"]
[{"$nulls":3},"MLTP3","[c]malthp + pi <==> g1p + malthx"]
[{"$nulls":3},"AMALT1","[c]malt + malttr --> glc-D + maltttr"]
[{"$nulls":3},"AMALT2","[c]malt + maltttr --> glc-D + maltpt"]
[{"$nulls":3},"AMALT3","[c]malt + maltpt --> glc-D + malthx"]
[{"$nulls":3},"AMALT4","[c]malt + malthx --> glc-D + malthp"]
[{"$nulls":3},"MLTG1","[c]h2o + malttr --> glc-D + malt"]
[{"$nulls":3},"MLTG2","[c]h2o + maltttr --> glc-D + malttr"]
[{"$nulls":3},"MLTG3","[c]h2o + maltpt --> glc-D + maltttr"]
[{"$nulls":3},"MLTG4","[c]h2o + malthx --> glc-D + maltpt"]
[{"$nulls":3},"MLTG5","[c]h2o + malthp --> glc-D + malthx"]
[{"$nulls":3},"MAN6PI","[c]man6p <==> f6p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GALS3","[c]h2o + melib --> gal + glc-D"]
[{"$nulls":3},"3HCINNMH","[c]3hcinnm + h + nadh + o2 --> dhcinnm + h2o + nad"]
[{"$nulls":3},"3HPPPNH","[c]3hpppn + h + nadh + o2 --> dhpppn + h2o + nad"]
[{"$nulls":3},"DHCINDO","[c]dhcinnm + o2 --> hkntd"]
[{"$nulls":3},"HPPPNDO","[c]dhpppn + o2 --> hkndd"]
[{"$nulls":3},"HKNDDH","[c]h2o + hkndd --> (2) h + op4en + succ"]
[{"$nulls":3},"HKNTDH","[c]h2o + hkntd --> fum + (2) h + op4en"]
[{"$nulls":3},"OP4ENH","[c]h2o + op4en --> 4h2opntn"]
[{"$nulls":3},"HOPNTAL","[c]4h2opntn --> acald + pyr"]
[{"$nulls":3},"ACALDi","[c]acald + coa + nad --> accoa + h + nadh",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"M1PD","[c]mnl1p + nad <==> f6p + h + nadh",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"AGDC","[c]acgam6p + h2o --> ac + gam6p"]
[{"$nulls":3},"G6PDA","[c]gam6p + h2o --> f6p + nh4"]
[{"$nulls":3},"ACNML","[c]acnam --> acmana + pyr"]
[{"$nulls":3},"TRE6PS","[c]g6p + udpg --> h + tre6p + udp"]
[{"$nulls":3},"TRE6PP","[c]h2o + tre6p --> pi + tre"]
[{"$nulls":3},"PACCOAL","[c]atp + coa + pac --> amp + phaccoa + ppi"]
[{"$nulls":3},"PFK_2","[c]atp + tag6p-D --> adp + h + tagdp-D"]
[{"$nulls":3},"PGMT","[c]g1p <==> g6p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"MCITL2","[c]micit <==> pyr + succ"]
[{"$nulls":3},"MCITS","[c]h2o + oaa + ppcoa --> 2mcit + coa + h"]
[{"$nulls":3},"MCITD","[c]2mcit --> 2mcacn + h2o"]
[{"$nulls":3},"ACCOAL","[c]atp + coa + ppa --> adp + pi + ppcoa"]
[{"$nulls":3},"PTA2","[c]pi + ppcoa --> coa + ppap"]
[{"$nulls":3},"RBK","[c]atp + rib-D --> adp + h + r5p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"RMI","[c]rmn <==> rml"]
[{"$nulls":3},"RMK","[c]atp + rml --> adp + h + rml1p"]
[{"$nulls":3},"RMPA","[c]rml1p <==> dhap + lald-L"]
[{"$nulls":3},"MMM2","[c]succoa --> mmcoa-R",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"KG6PDC","[c]3dgulnp + h + h2o --> co2tot + xu5p-L"]
[{"$nulls":3},"X5PL3E","[c]xu5p-L --> ru5p-L",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"SBTPD","[c]nad + sbt6p <==> f6p + h + nadh",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"TAUDO","[c]akg + o2 + taur + h2o --> aacald + co2tot + h + so3 + succ"]
[{"$nulls":3},"PPAKr","[c]adp + ppap <==> atp + ppa"]
[{"$nulls":3},"OBTFL","[c]2obut + coa --> for + ppcoa",{"$nulls":6},1,null,1]
[{"$nulls":3},"TREHe","[e]h2o + tre --> (2) glc-D"]
[{"$nulls":3},"TRE6PH","[c]h2o + tre6p --> g6p + glc-D"]
[{"$nulls":3},"TREH","[c]h2o + tre --> (2) glc-D",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"TARTD","[c]tartr-L --> h2o + oaa"]
[{"$nulls":3},"PEAMNO","[c]h2o + o2 + peamn --> h2o2 + nh4 + pacald"]
[{"$nulls":3},"ALTRH","[c]altrn --> 2ddglcn + h2o"]
[{"$nulls":3},"TAGURr","[c]altrn + nad <==> h + nadh + tagur"]
[{"$nulls":3},"GUI1","[c]glcur <==> fruur"]
[{"$nulls":3},"GUI2","[c]galur <==> tagur"]
[{"$nulls":3},"MNNH","[c]mana --> 2ddglcn + h2o"]
[{"$nulls":3},"MANAO","[c]mana + nad <==> fruur + h + nadh"]
[{"$nulls":3},"XYLI2i","[c]fru --> glc-D",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"XYLI1","[c]xyl-D <==> xylu-D",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"XYLK","[c]atp + xylu-D --> adp + h + xu5p-D"]
[{"$nulls":3},"DKGLCNR1","[c]25dkglcn + h + nadph --> 2dhguln + nadp"]
[{"$nulls":3},"HPYRRx","[c]h + hpyr + nadh --> glyc-R + nad",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"HPYRRy","[c]h + hpyr + nadph --> glyc-R + nadp",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GLCRD","[c]glcr --> 5dh4dglc + h2o"]
[{"$nulls":3},"MMCD","[c]h + mmcoa-S + h2o --> co2tot + ppcoa",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"PPCSCT","[c]ppcoa + succ --> ppa + succoa"]
[{"$nulls":3},"DKGLCNR2y","[c]25dkglcn + h + nadph --> 5dglcn + nadp"]
[{"$nulls":3},"2DGLCNRx","[c]2dhglcn + h + nadh --> glcn + nad"]
[{"$nulls":3},"2DGLCNRy","[c]2dhglcn + h + nadph --> glcn + nadp"]
[{"$nulls":3},"DKGLCNR2x","[c]25dkglcn + h + nadh --> 5dglcn + nad"]
[{"$nulls":3},"2DGULRx","[c]2dhguln + h + nadh --> idon-L + nad"]
[{"$nulls":3},"2DGULRy","[c]2dhguln + h + nadph --> idon-L + nadp"]
[{"$nulls":3},"DOGULNR","[c]23doguln + h + nadh --> 3dhguln + nad"]
[{"$nulls":3},"ICL","[c]icit --> glx + succ",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"MALS","[c]accoa + glx + h2o --> coa + h + mal-L",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"ME2","[c]mal-L + nadp + h2o --> co2tot + nadph + pyr",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PPCK","[c]atp + oaa + h2o --> adp + co2tot + pep",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PPA","[c]h2o + ppi --> h + (2) pi",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"PPC","[c]co2tot + pep --> h + oaa + pi",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"ME1","[c]mal-L + nad + h2o --> co2tot + nadh + pyr",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"MDRPD","[c]5mdru1p --> dkmpp + h2o"]
[{"$nulls":3},"DKMPPD2","[c]dkmpp + (3) h2o --> 2kmb + for + (6) h + pi"]
[{"$nulls":3},"PTRCTA","[c]akg + ptrc --> 4abutn + glu-L"]
[{"$nulls":3},"SSALx","[c]h2o + nad + sucsal --> (2) h + nadh + succ"]
[{"$nulls":3},"ABUTD","[c]4abutn + h2o + nad --> 4abut + (2) h + nadh"]
[{"$nulls":3},"MTRK","[c]5mtr + atp --> 5mdr1p + adp + h"]
[{"$nulls":3},"MTRI","[c]5mdr1p <==> 5mdru1p"]
[{"$nulls":3},"DKMPPD","[c]dkmpp + h2o + o2 --> 2kmb + for + (2) h + pi"]
[{"$nulls":3},"G5SADs","[c]glu5sa --> 1pyr5c + h + h2o"]
[{"$nulls":3},"UNK3","[c]2kmb + glu-L --> akg + met-L"]
[{"$nulls":3},"ACGS","[c]accoa + glu-L --> acglu + coa + h"]
[{"$nulls":3},"ACGK","[c]acglu + atp --> acg5p + adp",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"AGPR","[c]acg5sa + nadp + pi <==> acg5p + h + nadph"]
[{"$nulls":3},"ACOTA","[c]acorn + akg <==> acg5sa + glu-L"]
[{"$nulls":3},"NACODA","[c]acg5sa + h2o --> ac + glu5sa"]
[{"$nulls":3},"ACODA","[c]acorn + h2o --> ac + orn"]
[{"$nulls":3},"ARGSS","[c]asp-L + atp + citr-L --> amp + argsuc + h + ppi"]
[{"$nulls":3},"ARGSL","[c]argsuc <==> arg-L + fum"]
[{"$nulls":3},"OCBT","[c]cbp + orn <==> citr-L + h + pi"]
[{"$nulls":3},"AST","[c]arg-L + succoa --> coa + h + sucarg"]
[{"$nulls":3},"SOTA","[c]akg + sucorn --> glu-L + sucgsa"]
[{"$nulls":3},"SADH","[c](2) h + (3) h2o + sucarg --> co2tot + (2) nh4 + sucorn",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"SGSAD","[c]h2o + nad + sucgsa --> (2) h + nadh + sucglu"]
[{"$nulls":3},"SGDS","[c]h2o + sucglu --> glu-L + succ"]
[{"$nulls":3},"CBPS","[c](2) atp + gln-L + h2o + hco3 --> (2) adp + cbp + glu-L + (2) h + pi"]
[{"$nulls":3},"SSALy","[c]h2o + nadp + sucsal --> (2) h + nadph + succ"]
[{"$nulls":3},"ABTA","[c]4abut + akg --> glu-L + sucsal"]
[{"$nulls":3},"GSPMDA","[c]gtspmd + h2o --> gthrd + spmd"]
[{"$nulls":3},"GSPMDS","[c]atp + gthrd + spmd --> adp + gtspmd + h + pi",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"MTAN","[c]5mta + h2o --> 5mtr + ade"]
[{"$nulls":3},"G5SD","[c]glu5p + h + nadph --> glu5sa + nadp + pi"]
[{"$nulls":3},"GLU5K","[c]atp + glu-L --> adp + glu5p",{"$nulls":6},1,null,1]
[{"$nulls":3},"P5CR","[c]1pyr5c + (2) h + nadph --> nadp + pro-L"]
[{"$nulls":3},"P5CD","[c]1pyr5c + (2) h2o + nad --> glu-L + h + nadh"]
[{"$nulls":3},"PROD2","[c]fad + pro-L --> 1pyr5c + fadh2 + h"]
[{"$nulls":3},"ARGDC","[c]arg-L + h + h2o --> agm + co2tot"]
[{"$nulls":3},"AGMT","[c]agm + h2o --> ptrc + urea"]
[{"$nulls":3},"ORNDC","[c]h + orn + h2o --> co2tot + ptrc",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"ADMDCr","[c]amet + h + h2o <==> ametam + co2tot"]
[{"$nulls":3},"SPMS","[c]ametam + ptrc --> 5mta + h + spmd"]
[{"$nulls":3},"SPMDAT1","[c]accoa + spmd --> N1aspmd + coa + h"]
[{"$nulls":3},"SPMDAT2","[c]accoa + spmd --> coa + h + n8aspmd"]
[{"$nulls":3},"ORNTA","[c]akg + orn --> glu-L + glu5sa"]
[{"$nulls":3},"PPTGS","[c]uaagmda --> h + peptido_EC + udcpdp"]
[{"$nulls":3},"UDCPDP","[c]h2o + udcpdp --> h + pi + udcpp"]
[{"$nulls":3},"KDOPP","[c]h2o + kdo8p --> kdo + pi"]
[{"$nulls":3},"PEPT_EC","[c]cmp + h + (0.02) pe_EC <==> (0.02) 12dgr_EC + cdpea"]
[{"$nulls":3},"PAPA_EC","[c]h2o + (0.02) pa_EC --> (0.02) 12dgr_EC + pi"]
[{"$nulls":3},"ECAP_EC","[c]unagamuf --> eca_EC + h + udcpdp"]
[{"$nulls":3},"AACPS1","[c]ACP + atp + ttdca --> amp + myrsACP + ppi",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"AACPS2","[c]ACP + atp + ttdcea --> amp + ppi + tdeACP",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"AACPS3","[c]ACP + atp + hdca --> amp + palmACP + ppi",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"AACPS4","[c]ACP + atp + hdcea --> amp + hdeACP + ppi",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"AACPS5","[c]ACP + atp + ocdcea --> amp + octeACP + ppi",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"ALAALAr","[c](2) ala-D + atp <==> adp + alaala + h + pi"]
[{"$nulls":3},"DAGK_EC","[c](0.02) 12dgr_EC + atp --> adp + h + (0.02) pa_EC",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"ETHAAL","[c]etha --> acald + nh4"]
[{"$nulls":3},"GDMANE","[c]gdpddman --> gdpofuc"]
[{"$nulls":3},"GOFUCR","[c]gdpofuc + h + nadph --> gdpfuc + nadp"]
[{"$nulls":3},"UDPGALM","[c]udpgal --> udpgalfur"]
[{"$nulls":3},"GF6PTA","[c]f6p + gln-L --> gam6p + glu-L"]
[{"$nulls":3},"UAGDP","[c]acgam1p + h + utp --> ppi + uacgam"]
[{"$nulls":3},"G1PACT","[c]accoa + gam1p --> acgam1p + coa + h"]
[{"$nulls":3},"GPDDA1","[c]g3pc + h2o --> chol + glyc3p + h"]
[{"$nulls":3},"GPDDA2","[c]g3pe + h2o --> etha + glyc3p + h"]
[{"$nulls":3},"GPDDA3","[c]g3ps + h2o --> glyc3p + h + ser-L"]
[{"$nulls":3},"GPDDA4","[c]g3pg + h2o --> glyc + glyc3p + h"]
[{"$nulls":3},"GPDDA5","[c]g3pi + h2o --> glyc3p + h + inost"]
[{"$nulls":3},"GMAND","[c]gdpmann --> gdpddman + h2o"]
[{"$nulls":3},"S7PI","[c]s7p --> gmhep7p"]
[{"$nulls":3},"GMHEPPA","[c]gmhep17bp + h2o --> gmhep1p + pi"]
[{"$nulls":3},"KDOPS","[c]ara5p + h2o + pep --> kdo8p + pi"]
[{"$nulls":3},"KDOCT2","[c]ctp + kdo --> ckdo + ppi"]
[{"$nulls":3},"MOAT","[c]ckdo + lipidA --> cmp + h + kdolipid4"]
[{"$nulls":3},"MOAT2","[c]ckdo + kdolipid4 --> cmp + h + kdo2lipid4"]
[{"$nulls":3},"UAGAAT","[c]3hmrsACP + uacgam <==> ACP + u3aga"]
[{"$nulls":3},"LPADSS","[c]lipidX + u23ga --> h + lipidAds + udp"]
[{"$nulls":3},"UHGADA","[c]h2o + u3aga --> ac + u3hga"]
[{"$nulls":3},"U23GAAT","[c]3hmrsACP + u3hga --> ACP + h + u23ga"]
[{"$nulls":3},"TDSK","[c]atp + lipidAds --> adp + h + lipidA"]
[{"$nulls":3},"EDTXS1","[c]ddcaACP + kdo2lipid4 --> ACP + kdo2lipid4L"]
[{"$nulls":3},"EDTXS3","[c]hdeACP + kdo2lipid4 --> ACP + kdo2lipid4p"]
[{"$nulls":3},"MAN1PT2","[c]gdp + h + man1p --> gdpmann + pi"]
[{"$nulls":3},"PAPPT3","[c]udcpp + ugmda --> uagmda + ump"]
[{"$nulls":3},"PGAMT","[c]gam1p <==> gam6p"]
[{"$nulls":3},"EDTXS4","[c]kdo2lipid4p + myrsACP --> ACP + lipa_cold"]
[{"$nulls":3},"EDTXS2","[c]kdo2lipid4L + myrsACP --> ACP + lipa"]
[{"$nulls":3},"UAGCVT","[c]pep + uacgam --> pi + uaccg"]
[{"$nulls":3},"UAPGR","[c]h + nadph + uaccg --> nadp + uamr"]
[{"$nulls":3},"UAMAS","[c]ala-L + atp + uamr --> adp + h + pi + uama"]
[{"$nulls":3},"UAMAGS","[c]atp + glu-D + uama --> adp + h + pi + uamag"]
[{"$nulls":3},"UAAGDS","[c]26dap-M + atp + uamag --> adp + h + pi + ugmd"]
[{"$nulls":3},"UGMDDS","[c]alaala + atp + ugmd --> adp + h + pi + ugmda"]
[{"$nulls":3},"UAGPT3","[c]uacgam + uagmda --> h + uaagmda + udp"]
[{"$nulls":3},"GLUR","[c]glu-D <==> glu-L"]
[{"$nulls":3},"PLIPA3","[c]h2o + (0.02) pc_EC --> (0.02) agpc_EC + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[{"$nulls":3},"PLIPA1","[c]h2o + (0.02) pg_EC --> (0.02) agpg_EC + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[{"$nulls":3},"PLIPA2","[c]h2o + (0.02) pe_EC --> (0.02) agpe_EC + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[{"$nulls":3},"LPLIPA1","[c](0.02) agpg_EC + h2o --> g3pg + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[{"$nulls":3},"LPLIPA2","[c](0.02) agpe_EC + h2o --> g3pe + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[{"$nulls":3},"LPLIPA3","[c](0.02) agpc_EC + h2o --> g3pc + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[{"$nulls":3},"LPLIPA4","[c](0.02) agpe_EC + (0.02) pg_EC --> (0.02) apg_EC + g3pe"]
[{"$nulls":3},"LPLIPA5","[c](0.02) agpc_EC + (0.02) pg_EC --> (0.02) apg_EC + g3pc"]
[{"$nulls":3},"LPLIPA6","[c](0.02) agpg_EC + (0.02) pg_EC --> (0.02) apg_EC + g3pg"]
[{"$nulls":3},"AGMHE","[c]adphep-D,D --> adphep-L,D"]
[{"$nulls":3},"GMHEPAT","[c]atp + gmhep1p + h --> adphep-D,D + ppi"]
[{"$nulls":3},"GMHEPK","[c]atp + gmhep7p --> adp + gmhep17bp + h"]
[{"$nulls":3},"LPSSYN_EC","[c](3) adphep-L,D + (2) cdpea + (3) ckdo + lipa + (2) udpg --> (3) adp + (2) cdp + (3) cmp + (10) h + lps_EC + (2) udp"]
[{"$nulls":3},"G1PTT","[c]dttp + g1p + h --> dtdpglu + ppi"]
[{"$nulls":3},"TDPGDH","[c]dtdpglu --> dtdp4d6dg + h2o"]
[{"$nulls":3},"TDPDRE","[c]dtdp4d6dg --> dtdp4d6dm"]
[{"$nulls":3},"TDPDRR","[c]dtdp4d6dm + h + nadph --> dtdprmn + nadp"]
[{"$nulls":3},"MI1PP","[c]h2o + mi1p-D --> inost + pi"]
[{"$nulls":3},"UDPGD","[c]h2o + (2) nad + udpg --> (3) h + (2) nadh + udpglcur"]
[{"$nulls":3},"USHD","[c]h2o + u23ga --> (2) h + lipidX + ump"]
[{"$nulls":3},"ACGAMT","[c]uacgam + udcpp --> ump + unaga"]
[{"$nulls":3},"UAG2Ei","[c]uacgam --> uacmam"]
[{"$nulls":3},"UACMAMO","[c]h2o + (2) nad + uacmam --> (3) h + (2) nadh + uacmamu"]
[{"$nulls":3},"TDPADGAT","[c]accoa + dtdp4addg --> coa + dtdp4aaddg + h"]
[{"$nulls":3},"TDPAGTA","[c]dtdp4d6dg + glu-L --> akg + dtdp4addg"]
[{"$nulls":3},"AADDGT","[c]dtdp4aaddg + unagamu --> dtdp + h + unagamuf"]
[{"$nulls":3},"ACMAMUT","[c]uacmamu + unaga --> h + udp + unagamu"]
[{"$nulls":3},"ACONT","[c]cit <==> icit",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"CITL","[c]cit --> ac + oaa",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"FRD2","[c]fum + mql8 --> mqn8 + succ",1,null,0,{"$nulls":5},1]
[{"$nulls":3},"FRD3","[c]2dmmql8 + fum --> 2dmmq8 + succ",1,null,0,{"$nulls":5},1]
[{"$nulls":3},"FUM","[c]fum + h2o <==> mal-L",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"CS","[c]accoa + h2o + oaa --> cit + coa + h",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"ICDHyr","[c]icit + nadp + h2o <==> akg + co2tot + nadph",null,null,0,null,null,1,null,null,0]
[{"$nulls":3},"TEST_AKGDH","[c]akg + coa + nad + h2o --> co2tot + nadh + succoa",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"MDH","[c]mal-L + nad <==> h + nadh + oaa",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"MDH2","[c]mal-L + q8 --> oaa + q8h2",1,null,0,{"$nulls":5},1]
[{"$nulls":3},"MDH3","[c]mal-L + mqn8 --> mql8 + oaa",1,null,0,{"$nulls":5},1]
[{"$nulls":3},"SUCD1i","[c]fad + succ --> fadh2 + fum",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"SUCOAS","[c]atp + coa + succ <==> adp + pi + succoa",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PMDPHT","[c]5aprbu + h2o --> 4r5au + pi"]
[{"$nulls":3},"DNMPPA","[c]dhpmp + h2o --> dhnpt + pi"]
[{"$nulls":3},"NADPPPS","[c]h2o + nadp --> nad + pi",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"NMNN","[c]h2o + nmn --> h + ncam + r5p"]
[{"$nulls":3},"NADDPe","[e]h2o + nad --> amp + (2) h + nmn"]
[{"$nulls":3},"PPCDC","[c]4ppcys + h +h2o --> co2tot + pan4p"]
[{"$nulls":3},"DPCOAK","[c]atp + dpcoa --> adp + coa + h"]
[{"$nulls":3},"HYPOE","[c]h2o + pyam5p --> pi + pydam"]
[{"$nulls":3},"PYDXPP","[c]h2o + pydx5p --> pi + pydx"]
[{"$nulls":3},"PDXPP","[c]h2o + pdx5p --> pi + pydxn"]
[{"$nulls":3},"NMNDA","[c]h2o + nmn --> nh4 + nicrnt"]
[{"$nulls":3},"TMKr","[c]atp + thm <==> adp + h + thmmp"]
[{"$nulls":3},"PPNCL2","[c]4ppan + ctp + cys-L --> 4ppcys + cmp + h + ppi"]
[{"$nulls":3},"ACPS1","[c]apoACP + coa --> ACP + h + pap"]
[{"$nulls":3},"AMAOTr","[c]8aonn + amet <==> amob + dann"]
[{"$nulls":3},"BTS2","[c]cys-L + dtbt <==> ala-L + btn + (2) h"]
[{"$nulls":3},"DBTSr","[c]atp + co2tot + dann <==> adp + dtbt + (3) h + pi + h2o"]
[{"$nulls":3},"AOXSr","[c]ala-L + h + pmcoa + h2o <==> 8aonn + co2tot + coa"]
[{"$nulls":3},"BSORx","[c]btnso + h + nadh --> btn + h2o + nad"]
[{"$nulls":3},"BSORy","[c]btnso + h + nadph --> btn + h2o + nadp"]
[{"$nulls":3},"CBIAT","[c]atp + cbi + h2o <==> adocbi + pi + ppi"]
[{"$nulls":3},"CBLAT","[c]atp + cbl1 + h2o <==> adocbl + pi + ppi"]
[{"$nulls":3},"PNTK","[c]atp + pnto-R --> 4ppan + adp + h"]
[{"$nulls":3},"PTPATi","[c]atp + h + pan4p --> dpcoa + ppi"]
[{"$nulls":3},"ADOCBLS","[c]agdpcbi + rdmbzi --> adocbl + gmp + h"]
[{"$nulls":3},"NNDMBRT","[c]dmbzid + nicrnt --> 5prdmbz + h + nac"]
[{"$nulls":3},"ADOCBIK","[c]adocbi + atp --> adocbip + adp + h"]
[{"$nulls":3},"ACBIPGT","[c]adocbip + gtp + h --> agdpcbi + ppi"]
[{"$nulls":3},"HEMEOS","[c]frdp + h2o + pheme --> hemeO + ppi"]
[{"$nulls":3},"SHCHD2","[c]nad + shcl --> h + nadh + srch"]
[{"$nulls":3},"SHCHF","[c]fe2 + srch --> (3) h + sheme"]
[{"$nulls":3},"DXPRIi","[c]dxyl5p + h + nadph --> 2me4p + nadp"]
[{"$nulls":3},"DXPS","[c]g3p + h + pyr + h2o --> co2tot + dxyl5p"]
[{"$nulls":3},"DHBD","[c]23ddhb + nad <==> 23dhb + h + nadh"]
[{"$nulls":3},"ICHORT","[c]h2o + ichor --> 23ddhb + pyr"]
[{"$nulls":3},"ENTCS","[c](3) 23dhba + (3) seramp --> (6) amp + enter + (6) h"]
[{"$nulls":3},"DHBSr","[c]23dhb + atp <==> 23dhba + ppi"]
[{"$nulls":3},"SERASr","[c]atp + h + ser-L <==> ppi + seramp"]
[{"$nulls":3},"E4PD","[c]e4p + h2o + nad <==> 4per + (2) h + nadh"]
[{"$nulls":3},"DHFR","[c]dhf + h + nadph <==> nadp + thf"]
[{"$nulls":3},"DHNPA2","[c]dhnpt --> 6hmhpt + gcald"]
[{"$nulls":3},"DHFS","[c]atp + dhpt + glu-L --> adp + dhf + pi"]
[{"$nulls":3},"GTPCI","[c]gtp + h2o --> ahdt + for"]
[{"$nulls":3},"HPPK2","[c]6hmhpt + atp --> 6hmhptpp + amp + h"]
[{"$nulls":3},"DHPS2","[c]4abz + 6hmhptpp --> dhpt + h + ppi"]
[{"$nulls":3},"MECDPDH","[c]2mecdp + h --> h2mb4p + h2o"]
[{"$nulls":3},"GLUTRS","[c]atp + glu-L + trnaglu --> amp + glutrna + ppi"]
[{"$nulls":3},"ALATA_D2","[c]ala-D + pydx5p --> pyam5p + pyr"]
[{"$nulls":3},"ALATA_L2","[c]ala-L + pydx5p --> pyam5p + pyr"]
[{"$nulls":3},"GTHOr","[c]gthox + h + nadph <==> (2) gthrd + nadp",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GLUCYS","[c]atp + cys-L + glu-L --> adp + glucys + h + pi"]
[{"$nulls":3},"GTHS","[c]atp + glucys + gly --> adp + gthrd + h + pi"]
[{"$nulls":3},"GLUTRR","[c]glutrna + h + nadph --> glu1sa + nadp + trnaglu"]
[{"$nulls":3},"PPBNGS","[c](2) 5aop --> h + (2) h2o + ppbng"]
[{"$nulls":3},"HMBS","[c]h2o + (4) ppbng --> hmbil + (4) nh4"]
[{"$nulls":3},"UPP3S","[c]hmbil --> h2o + uppg3"]
[{"$nulls":3},"UPPDC1","[c](4) h + uppg3 + (4) h2o --> (4) co2tot + cpppg3"]
[{"$nulls":3},"CPPPGO","[c]cpppg3 + (2) h + o2 --> (2) co2tot + pppg9"]
[{"$nulls":3},"PPPGO","[c](1.5) o2 + pppg9 --> (3) h2o + ppp9"]
[{"$nulls":3},"FCLT","[c]fe2 + ppp9 --> (2) h + pheme"]
[{"$nulls":3},"G1SATi","[c]glu1sa --> 5aop"]
[{"$nulls":3},"UPP3MT","[c](2) amet + uppg3 --> (2) ahcys + h + shcl"]
[{"$nulls":3},"IPDDIi","[c]ipdp --> dmpp"]
[{"$nulls":3},"DMATT","[c]dmpp + ipdp --> grdp + ppi"]
[{"$nulls":3},"GRTT","[c]grdp + ipdp --> frdp + ppi"]
[{"$nulls":3},"OCTDPS","[c]frdp + (5) ipdp --> octdp + (5) ppi"]
[{"$nulls":3},"MEPCT","[c]2me4p + ctp + h --> 4c2me + ppi"]
[{"$nulls":3},"CDPMEK","[c]4c2me + atp --> 2p4c2me + adp + h"]
[{"$nulls":3},"MECDPS","[c]2p4c2me --> 2mecdp + cmp"]
[{"$nulls":3},"NADDP","[c]h2o + nad --> amp + (2) h + nmn"]
[{"$nulls":3},"DMPPS","[c]h + h2mb4p + nadh --> dmpp + h2o + nad"]
[{"$nulls":3},"IPDPS","[c]h + h2mb4p + nadh --> h2o + ipdp + nad"]
[{"$nulls":3},"DHNAOT","[c]dhna + octdp + h2o --> 2dmmq8 + co2tot + h + ppi"]
[{"$nulls":3},"NPHS","[c]sbzcoa --> coa + dhna"]
[{"$nulls":3},"SUCBZS","[c]2shchc --> h2o + sucbz"]
[{"$nulls":3},"OXGDC2","[c]akg + h + thmpp + h2o --> co2tot + ssaltpp"]
[{"$nulls":3},"SHCHCS2","[c]ichor + ssaltpp --> 2shchc + pyr + thmpp"]
[{"$nulls":3},"SUCBZL","[c]atp + coa + sucbz --> amp + ppi + sbzcoa"]
[{"$nulls":3},"ICHORSi","[c]chor --> ichor"]
[{"$nulls":3},"AMMQT8_2","[c]2dmmq8 + amet --> ahcys + h + mqn8"]
[{"$nulls":3},"QULNS","[c]dhap + iasp --> h + (2) h2o + pi + quln"]
[{"$nulls":3},"ASPO3","[c]asp-L + q8 --> iasp + q8h2",1,{"$nulls":7},1]
[{"$nulls":3},"ASPO4","[c]asp-L + mqn8 --> iasp + mql8",1,{"$nulls":7},1]
[{"$nulls":3},"ASPO5","[c]asp-L + fum --> iasp + succ"]
[{"$nulls":3},"ASPO6","[c]asp-L + o2 --> h2o2 + iasp"]
[{"$nulls":3},"NNDPR","[c](2) h + prpp + quln + h2o --> co2tot + nicrnt + ppi"]
[{"$nulls":3},"NNAT","[c]atp + h + nicrnt --> dnad + ppi",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"NMNAT","[c]atp + h + nmn --> nad + ppi",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"NADS1","[c]atp + dnad + nh4 --> amp + h + nad + ppi",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"DNTPPA","[c]ahdt + h2o --> dhpmp + h + ppi"]
[{"$nulls":3},"ADCS","[c]chor + gln-L --> 4adcho + glu-L"]
[{"$nulls":3},"ADCL","[c]4adcho --> 4abz + h + pyr"]
[{"$nulls":3},"MOHMT","[c]3mob + h2o + mlthf --> 2dhp + thf"]
[{"$nulls":3},"PANTS","[c]ala-B + atp + pant-R --> amp + h + pnto-R + ppi"]
[{"$nulls":3},"ASP1DC","[c]asp-L + h + h2o --> ala-B + co2tot"]
[{"$nulls":3},"DPR","[c]2dhp + h + nadph --> nadp + pant-R"]
[{"$nulls":3},"PDX5PS","[c]dxyl5p + nad + phthr --> co2tot + h + h2o + nadh + pdx5p + pi"]
[{"$nulls":3},"PERD","[c]4per + nad <==> h + nadh + ohpb"]
[{"$nulls":3},"PDX5PO","[c]o2 + pdx5p <==> h2o2 + pydx5p"]
[{"$nulls":3},"PYAM5PO","[c]h2o + o2 + pyam5p --> h2o2 + nh4 + pydx5p"]
[{"$nulls":3},"PYDXNK","[c]atp + pydxn --> adp + h + pdx5p",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"PYDAMK","[c]atp + pydam --> adp + h + pyam5p",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"PYDXK","[c]atp + pydx --> adp + h + pydx5p",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"RZ5PP","[c]5prdmbz + h2o --> pi + rdmbzi"]
[{"$nulls":3},"NNAM","[c]h2o + ncam --> nac + nh4"]
[{"$nulls":3},"NAMNPP","[c]atp + h2o + nac + prpp --> adp + nicrnt + pi + ppi",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"GTPCII2","[c]gtp + (3) h2o --> 25drapp + for + (2) h + ppi",{"$nulls":6},1,null,1]
[{"$nulls":3},"DB4PS","[c]ru5p-D --> db4p + for + h",{"$nulls":6},1,null,1]
[{"$nulls":3},"APRAUR","[c]5apru + h + nadph --> 5aprbu + nadp"]
[{"$nulls":3},"DHPPDA2","[c]25drapp + h + h2o --> 5apru + nh4"]
[{"$nulls":3},"RBFSa","[c]4r5au + db4p --> dmlz + (2) h2o + pi"]
[{"$nulls":3},"RBFK","[c]atp + ribflv --> adp + fmn + h"]
[{"$nulls":3},"FMNAT","[c]atp + fmn + h --> fad + ppi"]
[{"$nulls":3},"RBFSb","[c](2) dmlz --> 4r5au + ribflv"]
[{"$nulls":3},"OHPBAT","[c]glu-L + ohpb <==> akg + phthr"]
[{"$nulls":3},"AMPMS","[c]air + h2o --> 4ampm + (2) for + (4) h"]
[{"$nulls":3},"PMPK","[c]4ampm + atp --> 2mahmp + adp"]
[{"$nulls":3},"HMPK1","[c]4ahmmp + atp --> 4ampm + adp + h"]
[{"$nulls":3},"TMPPP","[c]2mahmp + 4mpetz + h --> ppi + thmmp"]
[{"$nulls":3},"TMPKr","[c]atp + thmmp <==> adp + thmpp"]
[{"$nulls":3},"HETZK","[c]4mhetz + atp --> 4mpetz + adp + h"]
[{"$nulls":3},"THZPSN","[c]atp + cys-L + dxyl5p + tyr-L --> 4hba + 4mpetz + ala-L + amp + co2tot + h + ppi"]
[{"$nulls":3},"4HTHRS","[c]h2o + phthr --> 4hthr + pi"]
[{"$nulls":3},"HBZOPT","[c]4hbz + octdp --> 3ophb + ppi"]
[{"$nulls":3},"OPHHX","[c]2oph + (0.5) o2 --> 2ohph"]
[{"$nulls":3},"CHRPL","[c]chor --> 4hbz + pyr"]
[{"$nulls":3},"OPHBDC","[c]3ophb + h + h2o --> 2oph + co2tot"]
[{"$nulls":3},"OMBZLM","[c]2ombzl + amet --> 2ommbl + ahcys + h"]
[{"$nulls":3},"OMMBLHX","[c]2ommbl + (0.5) o2 --> 2omhmbl"]
[{"$nulls":3},"OHPHM","[c]2ohph + amet --> 2omph + ahcys + h"]
[{"$nulls":3},"DMQMT","[c]2omhmbl + amet --> ahcys + h + q8h2"]
[{"$nulls":3},"OMPHHX","[c]2omph + (0.5) o2 --> 2ombzl"]
[{"$nulls":3},"UDCPDPS","[c]frdp + (8) ipdp --> (8) ppi + udcpdp"]
[{"$nulls":3},"DXYLK","[c]atp + dxyl --> adp + dxyl5p + h"]
[{"$nulls":3},"NADK","[c]atp + nad --> adp + h + nadp",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"BPNT","[c]h2o + pap --> amp + pi"]
[{"$nulls":3},"ADSK","[c]aps + atp --> adp + h + paps"]
[{"$nulls":3},"SADT2","[c]atp + gtp + h2o + so4 --> aps + gdp + pi + ppi",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"SERAT","[c]accoa + ser-L <==> acser + coa"]
[{"$nulls":3},"PAPSR","[c]paps + trdrd --> (2) h + pap + so3 + trdox"]
[{"$nulls":3},"SULR","[c](3) h2o + h2s + (3) nadp <==> (5) h + (3) nadph + so3",null,null,-1,{"$nulls":5},-1]
[{"$nulls":3},"CYSS","[c]acser + h2s --> ac + cys-L + h"]
[{"$nulls":3},"TRPAS1","[c]cys-L + h2o --> h2s + nh4 + pyr",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"GCALDD","[c]gcald + h2o + nad --> glyclt + (2) h + nadh"]
[{"$nulls":3},"MTHFC","[c]h2o + methf <==> 10fthf"]
[{"$nulls":3},"MTHFD","[c]mlthf + nadp <==> h + methf + nadph"]
[{"$nulls":3},"GLYCL","[c]gly + nad + thf + h2o --> co2tot + mlthf + nadh + nh4",{"$nulls":6},1,null,1]
[{"$nulls":3},"MTHFR2","[c]h + mlthf + nadh --> 5mthf + nad"]
[{"$nulls":3},"FTHFD","[c]10fthf + h2o --> for + h + thf",{"$nulls":6},1,null,1]
[{"$nulls":3},"GLUDC","[c]glu-L + h + h2o --> 4abut + co2tot",{"$nulls":6},1,null,1]
[{"$nulls":3},"GLUDy","[c]glu-L + h2o + nadp <==> akg + h + nadph + nh4",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GLNS","[c]atp + glu-L + nh4 --> adp + gln-L + h + pi",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GLUSy","[c]akg + gln-L + h + nadph --> (2) glu-L + nadp",null,null,0,null,null,1,null,null,0]
[{"$nulls":3},"GLUN","[c]gln-L + h2o --> glu-L + nh4",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"SERD_D","[c]ser-D --> nh4 + pyr"]
[{"$nulls":3},"GHMT2","[c]ser-L + thf --> gly + h2o + mlthf"]
[{"$nulls":3},"GLYATi","[c]2aobut + coa --> accoa + gly"]
[{"$nulls":3},"PGCD","[c]3pg + nad --> 3php + h + nadh",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PSP_L","[c]h2o + pser-L --> pi + ser-L",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PSERT","[c]3php + glu-L --> akg + pser-L",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"SERD_L","[c]ser-L --> nh4 + pyr",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"THRD","[c]nad + thr-L --> 2aobut + h + nadh"]
[{"$nulls":3},"PDH","[c]coa + nad + pyr + h2o --> accoa + co2tot + nadh",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"G1PP","[c]g1p + h2o --> glc-D + pi",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"ENO","[c]2pg <==> h2o + pep",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"FBA","[c]fdp <==> dhap + g3p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"FBP","[c]fdp + h2o --> f6p + pi",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"F6PA","[c]f6p <==> dha + g3p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GAPD","[c]g3p + nad + pi <==> 13dpg + h + nadh",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GLCS1","[c]adpglc --> adp + glycogen + h"]
[{"$nulls":3},"GLGC","[c]atp + g1p + h --> adpglc + ppi",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"GLCP","[c]glycogen + pi --> g1p"]
[{"$nulls":3},"HEX1","[c]atp + glc-D --> adp + g6p + h",null,null,0,null,null,1,null,null,0]
[{"$nulls":3},"PGM","[c]2pg <==> 3pg",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PFK","[c]atp + f6p --> adp + fdp + h",null,null,0,null,1,{"$nulls":3},1]
[{"$nulls":3},"PGI","[c]g6p <==> f6p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PGK","[c]3pg + atp <==> 13dpg + adp",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PPS","[c]atp + h2o + pyr --> amp + (2) h + pep + pi",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PYK","[c]adp + h + pep --> atp + pyr",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"TPI","[c]dhap <==> g3p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"TRSAR","[c]2h3oppan + h + nadh --> glyc-R + nad"]
[{"$nulls":3},"GLXCL","[c](2) glx + h + h2o --> 2h3oppan + co2tot",{"$nulls":6},1,null,1]
[{"$nulls":3},"GLYCK","[c]atp + glyc-R --> 3pg + adp + h",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GLYCLTDy","[c]glx + h + nadph --> glyclt + nadp",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GLYCLTDx","[c]glx + h + nadh --> glyclt + nad",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PRMICIi","[c]prfp --> prlp"]
[{"$nulls":3},"IGPDH","[c]eig3p --> h2o + imacp"]
[{"$nulls":3},"HISTP","[c]h2o + hisp --> histd + pi"]
[{"$nulls":3},"HSTPT","[c]glu-L + imacp --> akg + hisp"]
[{"$nulls":3},"HISTD","[c]h2o + histd + (2) nad --> (3) h + his-L + (2) nadh"]
[{"$nulls":3},"IG3PS","[c]gln-L + prlp --> aicar + eig3p + glu-L + h"]
[{"$nulls":3},"ATPPRT","[c]atp + prpp --> ppi + prbatp"]
[{"$nulls":3},"PRATPP","[c]h2o + prbatp --> h + ppi + prbamp"]
[{"$nulls":3},"PRAMPC","[c]h2o + prbamp --> prfp"]
[{"$nulls":3},"PRPPS","[c]atp + r5p <==> amp + h + prpp",null,null,0,null,null,1,null,null,0]
[{"$nulls":3},"ACCOACr","[c]accoa + atp + hco3 <==> adp + h + malcoa + pi"]
[{"$nulls":3},"ACACT1r","[c](2) accoa <==> aacoa + coa",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"CDAPPA_EC","[c](0.02) cdpdag1 + h2o --> cmp + (2) h + (0.02) pa_EC"]
[{"$nulls":3},"DASYN_EC","[c]ctp + h + (0.02) pa_EC <==> (0.02) cdpdag1 + ppi",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"CLPNS_EC","[c](0.04) pg_EC <==> (0.02) clpn_EC + glyc"]
[{"$nulls":3},"C140SN","[c]actACP + (17) h + (5) malACP + (12) nadph --> (5) ACP + (5) co2tot + h2o + myrsACP + (12) nadp",{"$nulls":6},1,null,1]
[{"$nulls":3},"C120SN","[c]actACP + (14) h + (4) malACP + (10) nadph --> (4) ACP + (4) co2tot + ddcaACP + h2o + (10) nadp"]
[{"$nulls":3},"MACPD","[c]h + malACP + h2o --> acACP + co2tot",{"$nulls":6},1,null,1]
[{"$nulls":3},"KAS14","[c]acACP + h + malACP + h2o --> ACP + actACP + co2tot",{"$nulls":6},1,null,1]
[{"$nulls":3},"MCOATA","[c]ACP + malcoa <==> coa + malACP"]
[{"$nulls":3},"C160SN","[c]actACP + (20) h + (6) malACP + (14) nadph --> (6) ACP + (6) co2tot + h2o + (14) nadp + palmACP",{"$nulls":6},1,null,1]
[{"$nulls":3},"KAS16","[c]ddcaACP + (2) h + malACP + nadph + h2o --> 3hmrsACP + ACP + co2tot + nadp"]
[{"$nulls":3},"C181SN","[c]actACP + (22) h + (7) malACP + (15) nadph --> (7) ACP + (7) co2tot + h2o + (15) nadp + octeACP"]
[{"$nulls":3},"C141SN","[c]actACP + (16) h + (5) malACP + (11) nadph --> (5) ACP + (5) co2tot + h2o + (11) nadp + tdeACP"]
[{"$nulls":3},"KAS15","[c]accoa + h + malACP + h2o --> actACP + co2tot + coa",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"ACOATA","[c]ACP + accoa <==> acACP + coa"]
[{"$nulls":3},"C161SN","[c]actACP + (19) h + (6) malACP + (13) nadph --> (6) ACP + (6) co2tot + h2o + hdeACP + (13) nadp"]
[{"$nulls":3},"FAO2","[c]atp + (8) coa + (7) fad + (7) h2o + hdca + (7) nad --> (8) accoa + amp + (7) fadh2 + (7) h + (7) nadh + ppi"]
[{"$nulls":3},"FAO1","[c]atp + (7) coa + (6) fad + (6) h2o + (6) nad + ttdca --> (7) accoa + amp + (6) fadh2 + (6) h + (6) nadh + ppi"]
[{"$nulls":3},"FAO3","[c]atp + (9) coa + (8) fad + (8) h2o + (8) nad + ocdca --> (9) accoa + amp + (8) fadh2 + (8) h + (8) nadh + ppi"]
[{"$nulls":3},"PGPP_EC","[c]h2o + (0.02) pgp_EC --> (0.02) pg_EC + pi"]
[{"$nulls":3},"PGSA_EC","[c](0.02) cdpdag1 + glyc3p <==> cmp + h + (0.02) pgp_EC"]
[{"$nulls":3},"PASYN_EC","[c]glyc3p + (0.14) hdeACP + (0.04) myrsACP + octeACP + (0.72) palmACP + (0.1) tdeACP --> (2) ACP + (0.02) pa_EC"]
[{"$nulls":3},"PSD_EC","[c]h + (0.02) ps_EC + h2o --> co2tot + (0.02) pe_EC",{"$nulls":6},1,null,1]
[{"$nulls":3},"PSSA_EC","[c](0.02) cdpdag1 + ser-L <==> cmp + h + (0.02) ps_EC"]
[{"$nulls":3},"AHC","[c]ahcys + h2o <==> adn + hcys-L"]
[{"$nulls":3},"DHPTDC","[c]dhptd --> h2o + hmfurn"]
[{"$nulls":3},"RHCCE","[c]rhcys --> dhptd + hcys-L"]
[{"$nulls":3},"HSST","[c]hom-L + succoa --> coa + suchms"]
[{"$nulls":3},"SHSL1","[c]cys-L + suchms --> cyst-L + h + succ"]
[{"$nulls":3},"CYSTL","[c]cyst-L + h2o --> hcys-L + nh4 + pyr"]
[{"$nulls":3},"METS","[c]5mthf + hcys-L --> met-L + thf"]
[{"$nulls":3},"METAT","[c]atp + h2o + met-L --> amet + pi + ppi"]
[{"$nulls":3},"AHCYSNS","[c]ahcys + h2o --> ade + rhcys"]
[{"$nulls":3},"LGTHL","[c]gthrd + mthgxl --> lgt-S"]
[{"$nulls":3},"GLYOX","[c]h2o + lgt-S --> gthrd + h + lac-D"]
[{"$nulls":3},"MGSA","[c]dhap --> mthgxl + pi"]
[{"$nulls":3},"UGLYCH","[c](2) h + (2) h2o + urdglyc --> co2tot + glx + (2) nh4"]
[{"$nulls":3},"ALLTN","[c]alltn + h2o --> alltt + h"]
[{"$nulls":3},"ALLTAH","[c]alltt + h2o --> urdglyc + urea"]
[{"$nulls":3},"CYNTAH","[c]cynt + (3) h + hco3  + (2) h2o --> (2) co2tot + nh4"]
[{"$nulls":3},"CMPN","[c]cmp + h2o --> csn + r5p"]
[{"$nulls":3},"ADA","[c]adn + h + h2o --> ins + nh4",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"DADA","[c]dad-2 + h + h2o --> din + nh4"]
[{"$nulls":3},"ADNK1","[c]adn + atp --> adp + amp + h",null,null,0,null,1,{"$nulls":3},1]
[{"$nulls":3},"ADK1","[c]amp + atp <==> (2) adp",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"DADK","[c]atp + damp <==> adp + dadp",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"ADK4","[c]amp + itp <==> adp + idp",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"ADK3","[c]amp + gtp <==> adp + gdp",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"AMPN","[c]amp + h2o --> ade + r5p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"AP4AH","[c]ap4a + h2o --> (2) adp + (2) h"]
[{"$nulls":3},"GP4GH","[c]gp4g + h2o --> (2) gdp + (2) h"]
[{"$nulls":3},"AP5AH","[c]ap5a + h2o --> adp + atp + (2) h"]
[{"$nulls":3},"ADPT","[c]ade + prpp --> amp + ppi",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"CYTD","[c]cytd + h + h2o --> nh4 + uri"]
[{"$nulls":3},"DCYTD","[c]dcyt + h + h2o --> duri + nh4"]
[{"$nulls":3},"CYTK2","[c]atp + dcmp <==> adp + dcdp"]
[{"$nulls":3},"CYTK1","[c]atp + cmp <==> adp + cdp"]
[{"$nulls":3},"UMPK","[c]atp + ump <==> adp + udp"]
[{"$nulls":3},"CSND","[c]csn + h + h2o --> nh4 + ura"]
[{"$nulls":3},"ADNCYC","[c]atp --> camp + ppi",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"DCTPD","[c]dctp + h + h2o --> dutp + nh4"]
[{"$nulls":3},"TMDPP","[c]pi + thymd <==> 2dr1p + thym"]
[{"$nulls":3},"DURIPP","[c]duri + pi <==> 2dr1p + ura"]
[{"$nulls":3},"NTPTP1","[c]dgtp + h2o --> dgsn + pppi"]
[{"$nulls":3},"NTPTP2","[c]gtp + h2o --> gsn + pppi",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"DUTPDP","[c]dutp + h2o --> dump + h + ppi"]
[{"$nulls":3},"GK1","[c]atp + gmp <==> adp + gdp"]
[{"$nulls":3},"DGK1","[c]atp + dgmp <==> adp + dgdp"]
[{"$nulls":3},"XPPT","[c]prpp + xan --> ppi + xmp",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"HXPRT","[c]hxan + prpp --> imp + ppi",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GUAPRT","[c]gua + prpp --> gmp + ppi"]
[{"$nulls":3},"INSK","[c]atp + ins --> adp + h + imp",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GSNK","[c]atp + gsn --> adp + gmp + h",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"NTPP3","[c]dctp + h2o --> dcmp + h + ppi"]
[{"$nulls":3},"NTPP4","[c]ctp + h2o --> cmp + h + ppi"]
[{"$nulls":3},"NTPP5","[c]datp + h2o --> damp + h + ppi",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"NTPP6","[c]atp + h2o --> amp + h + ppi",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"NTPP7","[c]dttp + h2o --> dtmp + h + ppi"]
[{"$nulls":3},"NTPP8","[c]h2o + utp --> h + ppi + ump"]
[{"$nulls":3},"NTPP1","[c]dgtp + h2o --> dgmp + h + ppi"]
[{"$nulls":3},"NTPP2","[c]gtp + h2o --> gmp + h + ppi"]
[{"$nulls":3},"NDPK1","[c]atp + gdp <==> adp + gtp",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"NDPK2","[c]atp + udp <==> adp + utp"]
[{"$nulls":3},"NDPK3","[c]atp + cdp <==> adp + ctp"]
[{"$nulls":3},"NDPK5","[c]atp + dgdp <==> adp + dgtp"]
[{"$nulls":3},"NDPK6","[c]atp + dudp <==> adp + dutp"]
[{"$nulls":3},"NDPK7","[c]atp + dcdp <==> adp + dctp"]
[{"$nulls":3},"NDPK8","[c]atp + dadp <==> adp + datp",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"NDPK4","[c]atp + dtdp <==> adp + dttp"]
[{"$nulls":3},"RNDR1","[c]adp + trdrd --> dadp + h2o + trdox",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"RNDR2","[c]gdp + trdrd --> dgdp + h2o + trdox"]
[{"$nulls":3},"RNDR4","[c]trdrd + udp --> dudp + h2o + trdox"]
[{"$nulls":3},"RNDR3","[c]cdp + trdrd --> dcdp + h2o + trdox"]
[{"$nulls":3},"RNTR1","[c]atp + trdrd --> datp + h2o + trdox",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"RNTR2","[c]gtp + trdrd --> dgtp + h2o + trdox",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"RNTR3","[c]ctp + trdrd --> dctp + h2o + trdox"]
[{"$nulls":3},"RNTR4","[c]trdrd + utp --> dutp + h2o + trdox"]
[{"$nulls":3},"URIDK2r","[c]atp + dump <==> adp + dudp"]
[{"$nulls":3},"DURIK1","[c]atp + duri --> adp + dump + h",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"TMDK1","[c]atp + thymd --> adp + dtmp + h",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"TMDS","[c]dump + mlthf --> dhf + dtmp"]
[{"$nulls":3},"DTMPK","[c]atp + dtmp <==> adp + dtdp"]
[{"$nulls":3},"URIK2","[c]gtp + uri --> gdp + h + ump",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"CYTDK2","[c]cytd + gtp --> cmp + gdp + h",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"PYNP2r","[c]pi + uri <==> r1p + ura"]
[{"$nulls":3},"UPPRT","[c]prpp + ura --> ppi + ump"]
[{"$nulls":3},"NTD1","[c]dump + h2o --> duri + pi"]
[{"$nulls":3},"NTD5","[c]dtmp + h2o --> pi + thymd"]
[{"$nulls":3},"NTD6","[c]damp + h2o --> dad-2 + pi",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"NTD8","[c]dgmp + h2o --> dgsn + pi"]
[{"$nulls":3},"NTD3","[c]dcmp + h2o --> dcyt + pi"]
[{"$nulls":3},"NTD4","[c]cmp + h2o --> cytd + pi"]
[{"$nulls":3},"NTD7","[c]amp + h2o --> adn + pi",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"NTD9","[c]gmp + h2o --> gsn + pi"]
[{"$nulls":3},"NTD11","[c]h2o + imp --> ins + pi",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"NTD10","[c]h2o + xmp --> pi + xtsn",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"NTD2","[c]h2o + ump --> pi + uri"]
[{"$nulls":3},"PUNP6","[c]din + pi <==> 2dr1p + hxan"]
[{"$nulls":3},"PUNP5","[c]ins + pi <==> hxan + r1p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PUNP2","[c]dad-2 + pi <==> 2dr1p + ade",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PUNP4","[c]dgsn + pi <==> 2dr1p + gua"]
[{"$nulls":3},"PUNP1","[c]adn + pi <==> ade + r1p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PUNP3","[c]gsn + pi <==> gua + r1p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PUNP7","[c]pi + xtsn <==> r1p + xan",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GUAD","[c]gua + h + h2o --> nh4 + xan",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"ADD","[c]ade + h + h2o --> hxan + nh4",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"L-LACD2","[c]lac-L + q8 --> pyr + q8h2",1,{"$nulls":7},1]
[{"$nulls":3},"L-LACD3","[c]lac-L + mqn8 --> mql8 + pyr",1,{"$nulls":7},1]
[{"$nulls":3},"CRNBTCT","[c]bbtcoa + crn <==> crncoa + gbbtn"]
[{"$nulls":3},"CRNCBCT","[c]crn + ctbtcoa <==> crncoa + ctbt"]
[{"$nulls":3},"CRNCDH","[c]crncoa <==> ctbtcoa + h2o"]
[{"$nulls":3},"CYTBD","(2) h[c] + (0.5) o2[c] + q8h2[c] --> (2) h[e] + h2o[c] + q8[c]",1,null,1,{"$nulls":5},1]
[{"$nulls":3},"CYTBO3","(2.5) h[c] + (0.5) o2[c] + q8h2[c] --> (2.5) h[e] + h2o[c] + q8[c]",1,null,1,{"$nulls":5},1]
[{"$nulls":3},"LDH_D2","[c]lac-D + q8 --> pyr + q8h2",1,null,0,{"$nulls":5},1]
[{"$nulls":3},"DMSOR1","[c]dmso + mql8 --> dms + h2o + mqn8",1,{"$nulls":7},1]
[{"$nulls":3},"DMSOR2","[c]2dmmql8 + dmso --> 2dmmq8 + dms + h2o",1,{"$nulls":7},1]
[{"$nulls":3},"TMAOR1","[c]h + mql8 + tmao --> h2o + mqn8 + tma",1,{"$nulls":7},1]
[{"$nulls":3},"TMAOR2","[c]2dmmql8 + h + tmao --> 2dmmq8 + h2o + tma",1,{"$nulls":7},1]
[{"$nulls":3},"FDH2","for[c] + (3) h[c] + q8[c] + h2o[c]--> co2tot[c] + (2) h[e] + q8h2[c]",1,null,1,{"$nulls":5},1]
[{"$nulls":3},"FDH3","for[c] + (3) h[c] + mqn8[c] + h2o[c] --> co2tot[c] + (2) h[e] + mql8[c]",1,null,1,{"$nulls":5},1]
[{"$nulls":3},"GLCDe","glc-D[e] + h2o[e] + q8[c] --> glcn[e] + h[e] + q8h2[c]",1,{"$nulls":7},1]
[{"$nulls":3},"G3PD7","[c]2dmmq8 + glyc3p --> 2dmmql8 + dhap",1,null,0,{"$nulls":5},1]
[{"$nulls":3},"G3PD6","[c]glyc3p + mqn8 --> dhap + mql8",1,null,0,{"$nulls":5},1]
[{"$nulls":3},"G3PD5","[c]glyc3p + q8 --> dhap + q8h2",1,null,0,{"$nulls":5},1]
[{"$nulls":3},"HYD3","2dmmq8[c] + (2) h[c] + h2[c] --> 2dmmql8[c] + (2) h[e]",1,null,1,{"$nulls":5},1]
[{"$nulls":3},"HYD1","(2) h[c] + h2[c] + q8[c] --> (2) h[e] + q8h2[c]",1,null,1,{"$nulls":5},1]
[{"$nulls":3},"HYD2","(2) h[c] + h2[c] + mqn8[c] --> (2) h[e] + mql8[c]",1,null,1,{"$nulls":5},1]
[{"$nulls":3},"NO3R1","(2) h[c] + no3[c] + q8h2[c] --> (2) h[e] + h2o[c] + no2[c] + q8[c]",1,null,1,{"$nulls":5},1]
[{"$nulls":3},"NO3R2","(2) h[c] + mql8[c] + no3[c] --> (2) h[e] + h2o[c] + mqn8[c] + no2[c]",1,null,1,{"$nulls":5},1]
[{"$nulls":3},"NADH5","[c]h + nadh + q8 --> nad + q8h2",1,null,1,{"$nulls":5},1]
[{"$nulls":3},"NADH9","[c]2dmmq8 + h + nadh --> 2dmmql8 + nad",1,null,1,{"$nulls":5},1]
[{"$nulls":3},"NADH10","[c]h + mqn8 + nadh --> mql8 + nad",1,null,1,{"$nulls":5},1]
[{"$nulls":3},"NTRIR2x","[c](5) h + (3) nadh + no2 --> (2) h2o + (3) nad + nh4",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"NADH6","(4.5) h[c] + nadh[c] + q8[c] --> (3.5) h[e] + nad[c] + q8h2[c]",1,null,0,{"$nulls":5},1]
[{"$nulls":3},"NADH7","(3) h[c] + mqn8[c] + nadh[c] --> (2) h[e] + mql8[c] + nad[c]",1,null,1,{"$nulls":5},1]
[{"$nulls":3},"NADH8","2dmmq8[c] + (3.8) h[c] + nadh[c] --> 2dmmql8[c] + (2.8) h[e] + nad[c]",1,null,0,{"$nulls":5},1]
[{"$nulls":3},"THD2","(2) h[e] + nadh[c] + nadp[c] --> (2) h[c] + nad[c] + nadph[c]",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"POX","[c](2) h2o + pyr + q8 --> ac + co2tot + q8h2",1,null,1,{"$nulls":5},1]
[{"$nulls":3},"SUCD4","[c]fadh2 + q8 <==> fad + q8h2",1,null,0,{"$nulls":5},1]
[{"$nulls":3},"TEST_NADTRHD","[c]nad + nadph --> nadh + nadp",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"TMAOR1e","h[e] + mql8[c] + tmao[e] --> h2o[e] + mqn8[c] + tma[e]",1,{"$nulls":7},1]
[{"$nulls":3},"TMAOR2e","2dmmql8[c] + h[e] + tmao[e] --> 2dmmq8[c] + h2o[e] + tma[e]",1,{"$nulls":7},1]
[{"$nulls":3},"DMSOR1e","dmso[e] + mql8[c] --> dms[e] + h2o[e] + mqn8[c]",1,{"$nulls":7},1]
[{"$nulls":3},"DMSOR2e","2dmmql8[c] + dmso[e] --> 2dmmq8[c] + dms[e] + h2o[e]",1,{"$nulls":7},1]
[{"$nulls":3},"TRDR","[c]h + nadph + trdox --> nadp + trdrd",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PGL","[c]6pgl + h2o --> 6pgc + h",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"EDA","[c]2ddg6p --> g3p + pyr",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"EDD","[c]6pgc --> 2ddg6p + h2o",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"GND","[c]6pgc + nadp + h2o --> co2tot + nadph + ru5p-D",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"RPE","[c]ru5p-D <==> xu5p-D"]
[{"$nulls":3},"RPI","[c]r5p <==> ru5p-D",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"TALA","[c]g3p + s7p <==> e4p + f6p",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"TKT1","[c]r5p + xu5p-D <==> g3p + s7p"]
[{"$nulls":3},"TKT2","[c]e4p + xu5p-D <==> f6p + g3p"]
[{"$nulls":3},"G6PDH2r","[c]g6p + nadp <==> 6pgl + h + nadph",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"GMPS2","[c]atp + gln-L + h2o + xmp --> amp + glu-L + gmp + (2) h + ppi"]
[{"$nulls":3},"IMPD","[c]h2o + imp + nad --> h + nadh + xmp"]
[{"$nulls":3},"GMPR","[c]gmp + (2) h + nadph --> imp + nadp + nh4"]
[{"$nulls":3},"ADSS","[c]asp-L + gtp + imp --> dcamp + gdp + (2) h + pi",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"ADSL2r","[c]25aics <==> aicar + fum"]
[{"$nulls":3},"ADSL1r","[c]dcamp <==> amp + fum"]
[{"$nulls":3},"PRASCS","[c]5aizc + asp-L + atp <==> 25aics + adp + h + pi",{"$nulls":6},1,null,1]
[{"$nulls":3},"PRAGSr","[c]atp + gly + pram <==> adp + gar + h + pi",{"$nulls":6},1,null,1]
[{"$nulls":3},"AIRC3","[c]5aizc <==> 5caiz"]
[{"$nulls":3},"GLUPRT","[c]gln-L + h2o + prpp --> glu-L + ppi + pram"]
[{"$nulls":3},"AICART","[c]10fthf + aicar <==> fprica + thf"]
[{"$nulls":3},"IMPC","[c]h2o + imp <==> fprica"]
[{"$nulls":3},"AIRC2","[c]air + atp + hco3 --> 5caiz + adp + h + pi",{"$nulls":6},1,null,1]
[{"$nulls":3},"PRFGS","[c]atp + fgam + gln-L + h2o --> adp + fpram + glu-L + h + pi",{"$nulls":6},1,null,1]
[{"$nulls":3},"PRAIS","[c]atp + fpram --> adp + air + (2) h + pi",{"$nulls":6},1,null,1]
[{"$nulls":3},"GARFT","[c]10fthf + gar <==> fgam + h + thf"]
[{"$nulls":3},"GART","[c]atp + for + gar --> adp + fgam + h + pi"]
[{"$nulls":3},"ASPCT","[c]asp-L + cbp --> cbasp + h + pi"]
[{"$nulls":3},"DHORTS","[c]dhor-S + h2o <==> cbasp + h"]
[{"$nulls":3},"DHORD2","[c]dhor-S + q8 --> orot + q8h2",1,{"$nulls":7},1]
[{"$nulls":3},"DHORD5","[c]dhor-S + mqn8 --> mql8 + orot",1,{"$nulls":7},1]
[{"$nulls":3},"ORPT","[c]orot5p + ppi <==> orot + prpp"]
[{"$nulls":3},"OMPDC","[c]h + orot5p + h2o --> co2tot + ump"]
[{"$nulls":3},"CTPS2","[c]atp + gln-L + h2o + utp --> adp + ctp + glu-L + (2) h + pi",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"CBMK","[c]atp + co2tot + nh4 --> adp + cbp + (2) h + h2o",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"AMANAPE","[c]acmanap --> acgam6p"]
[{"$nulls":3},"AMANK","[c]acmana + atp --> acmanap + adp + h"]
[{"$nulls":3},"ALLTNt2r","alltn[e] + h[e] <==> alltn[c] + h[c]"]
[{"$nulls":3},"ARGORNt7","arg-L[e] + orn[c] <==> arg-L[c] + orn[e]"]
[{"$nulls":3},"ACACt2","acac[e] + h[e] <==> acac[c] + h[c]"]
[{"$nulls":3},"BUTt2r","but[e] + h[e] <==> but[c] + h[c]"]
[{"$nulls":3},"CYNTt2","cynt[e] + h[e] --> cynt[c] + h[c]"]
[{"$nulls":3},"GALCTt2r","galct-D[e] + h[e] <==> galct-D[c] + h[c]"]
[{"$nulls":3},"GLCRt2r","glcr[e] + h[e] <==> glcr[c] + h[c]"]
[{"$nulls":3},"PPPNt2r","h[e] + pppn[e] <==> h[c] + pppn[c]"]
[{"$nulls":3},"HPPPNt2r","3hpppn[e] + h[e] <==> 3hpppn[c] + h[c]"]
[{"$nulls":3},"HCINNMt2r","3hcinnm[e] + h[e] <==> 3hcinnm[c] + h[c]"]
[{"$nulls":3},"GLUABUTt7","4abut[c] + glu-L[e] <==> 4abut[e] + glu-L[c]"]
[{"$nulls":3},"ALAt2r","ala-L[e] + h[e] <==> ala-L[c] + h[c]"]
[{"$nulls":3},"URAt2r","h[e] + ura[e] <==> h[c] + ura[c]"]
[{"$nulls":3},"GLYBt2r","glyb[e] + h[e] <==> glyb[c] + h[c]"]
[{"$nulls":3},"CHLabc","atp[c] + chol[e] + h2o[c] --> adp[c] + chol[c] + h[c] + pi[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"GLYBabc","atp[c] + glyb[e] + h2o[c] --> adp[c] + glyb[c] + h[c] + pi[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"TARTRt7","succ[c] + tartr-L[e] <==> succ[e] + tartr-L[c]"]
[{"$nulls":3},"SUCCabc","atp[c] + h2o[c] + succ[e] --> adp[c] + h[c] + pi[c] + succ[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"GUAt2","gua[e] + h[e] --> gua[c] + h[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"XANt2","h[e] + xan[e] --> h[c] + xan[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"ACKr","[c]ac + atp <==> actp + adp",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"ACS","[c]ac + atp + coa --> accoa + amp + ppi",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"ADHEr","[c]accoa + (2) h + (2) nadh <==> coa + etoh + (2) nad",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"LDH_D","[c]lac-D + nad <==> h + nadh + pyr",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"FHL","[c]for + h + h2o --> co2tot + h2",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PTAr","[c]accoa + pi <==> actp + coa",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"PFL","[c]coa + pyr --> accoa + for",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"SDPTA","[c]akg + sl26da <==> glu-L + sl2a6o"]
[{"$nulls":3},"ASAD","[c]aspsa + nadp + pi <==> 4pasp + h + nadph"]
[{"$nulls":3},"DHDPS","[c]aspsa + pyr --> 23dhdp + h + (2) h2o"]
[{"$nulls":3},"DHDPRy","[c]23dhdp + h + nadph --> nadp + thdp"]
[{"$nulls":3},"THDPS","[c]h2o + succoa + thdp --> coa + sl2a6o"]
[{"$nulls":3},"SDPDS","[c]h2o + sl26da --> 26dap-LL + succ"]
[{"$nulls":3},"DAPE","[c]26dap-LL <==> 26dap-M"]
[{"$nulls":3},"LYSDC","[c]h + lys-L + h2o --> 15dap + co2tot"]
[{"$nulls":3},"THRAr","[c]thr-L <==> acald + gly",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"DAPDC","[c]26dap-M + h + h2o --> co2tot + lys-L"]
[{"$nulls":3},"HSDy","[c]hom-L + nadp <==> aspsa + h + nadph"]
[{"$nulls":3},"ASPK","[c]asp-L + atp <==> 4pasp + adp",{"$nulls":6},1,null,1]
[{"$nulls":3},"HSK","[c]atp + hom-L --> adp + h + phom",{"$nulls":6},1,null,1]
[{"$nulls":3},"THRS","[c]h2o + phom --> pi + thr-L"]
[{"$nulls":3},"12PPDt","12ppd-S[e] <==> 12ppd-S[c]"]
[{"$nulls":3},"NMNt7","h2o[c] + nmn[e] --> h[c] + ncam[c] + r5p[c]"]
[{"$nulls":3},"ACALDt","acald[e] <==> acald[c]"]
[{"$nulls":3},"GUAt","gua[e] <==> gua[c]"]
[{"$nulls":3},"HYXNt","hxan[e] <==> hxan[c]"]
[{"$nulls":3},"XANt","xan[e] <==> xan[c]"]
[{"$nulls":3},"NACUP","nac[e] --> nac[c]"]
[{"$nulls":3},"ASNabc","asn-L[e] + atp[c] + h2o[c] --> adp[c] + asn-L[c] + h[c] + pi[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"ASNt2r","asn-L[e] + h[e] <==> asn-L[c] + h[c]"]
[{"$nulls":3},"DAPabc","26dap-M[e] + atp[c] + h2o[c] --> 26dap-M[c] + adp[c] + h[c] + pi[c]"]
[{"$nulls":3},"CYSabc","atp[c] + cys-L[e] + h2o[c] --> adp[c] + cys-L[c] + h[c] + pi[c]"]
[{"$nulls":3},"ACt2r","ac[e] + h[e] <==> ac[c] + h[c]"]
[{"$nulls":3},"ETOHt2r","etoh[e] + h[e] <==> etoh[c] + h[c]"]
[{"$nulls":3},"PYRt2r","h[e] + pyr[e] <==> h[c] + pyr[c]"]
[{"$nulls":3},"O2t","o2[e] <==> o2[c]",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"CO2t","co2tot[e] + h2o[c] <==> co2tot[c] + h2o[e]",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"H2Ot","h2o[e] <==> h2o[c]"]
[{"$nulls":3},"DHAt","dha[e] <==> dha[c]"]
[{"$nulls":3},"NH3t","nh4[e] <==> nh4[c]",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"ARBt2r","arab-L[e] + h[e] <==> arab-L[c] + h[c]"]
[{"$nulls":3},"ARBabc","arab-L[e] + atp[c] + h2o[c] --> adp[c] + arab-L[c] + h[c] + pi[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"HISt2r","h[e] + his-L[e] <==> h[c] + his-L[c]"]
[{"$nulls":3},"PHEt2r","h[e] + phe-L[e] <==> h[c] + phe-L[c]"]
[{"$nulls":3},"LEUt2r","h[e] + leu-L[e] <==> h[c] + leu-L[c]"]
[{"$nulls":3},"VALt2r","h[e] + val-L[e] <==> h[c] + val-L[c]"]
[{"$nulls":3},"ILEt2r","h[e] + ile-L[e] <==> h[c] + ile-L[c]"]
[{"$nulls":3},"CBL1abc","atp[c] + cbl1[e] + h2o[c] --> adp[c] + cbl1[c] + h[c] + pi[c]"]
[{"$nulls":3},"CADVt","15dap[c] + h[e] + lys-L[e] --> 15dap[e] + h[c] + lys-L[c]"]
[{"$nulls":3},"CRNt7","crn[e] + gbbtn[c] --> crn[c] + gbbtn[e]"]
[{"$nulls":3},"NAt3_1","h[e] + na1[c] <==> h[c] + na1[e]"]
[{"$nulls":3},"CITt7","cit[e] + succ[c] --> cit[c] + succ[e]"]
[{"$nulls":3},"CSNt2","csn[e] + h[e] --> csn[c] + h[c]"]
[{"$nulls":3},"MALTpts","malt[e] + pep[c] --> malt6p[c] + pyr[c]"]
[{"$nulls":3},"ACGApts","acgam[e] + pep[c] --> acgam6p[c] + pyr[c]"]
[{"$nulls":3},"DALAt2r","ala-D[e] + h[e] <==> ala-D[c] + h[c]"]
[{"$nulls":3},"DSERt2r","h[e] + ser-D[e] <==> h[c] + ser-D[c]"]
[{"$nulls":3},"GLYt2r","gly[e] + h[e] <==> gly[c] + h[c]"]
[{"$nulls":3},"SULabc","atp[c] + h2o[c] + so4[e] --> adp[c] + h[c] + pi[c] + so4[c]"]
[{"$nulls":3},"ASPt2_2","asp-L[e] + (2) h[e] --> asp-L[c] + (2) h[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"FUMt2_2","fum[e] + (2) h[e] --> fum[c] + (2) h[c]"]
[{"$nulls":3},"MALt2_2","(2) h[e] + mal-L[e] --> (2) h[c] + mal-L[c]"]
[{"$nulls":3},"SUCCt2_2","(2) h[e] + succ[e] --> (2) h[c] + succ[c]"]
[{"$nulls":3},"ASPt2_3","asp-L[e] + (3) h[e] --> asp-L[c] + (3) h[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"MALt2_3","(3) h[e] + mal-L[e] --> (3) h[c] + mal-L[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"SUCCt2_3","(3) h[e] + succ[e] --> (3) h[c] + succ[c]"]
[{"$nulls":3},"SUCCt2b","h[c] + succ[c] --> h[e] + succ[e]"]
[{"$nulls":3},"FUMt2_3","fum[e] + (3) h[e] --> fum[c] + (3) h[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"SUCFUMt","fum[e] + succ[c] <==> fum[c] + succ[e]"]
[{"$nulls":3},"GALCTNt2r","galctn-D[e] + h[e] <==> galctn-D[c] + h[c]"]
[{"$nulls":3},"GALURt2r","galur[e] + h[e] <==> galur[c] + h[c]"]
[{"$nulls":3},"GLCURt2r","glcur[e] + h[e] <==> glcur[c] + h[c]"]
[{"$nulls":3},"OCDCAt2","h[e] + ocdca[e] --> h[c] + ocdca[c]"]
[{"$nulls":3},"HDCAt2","h[e] + hdca[e] --> h[c] + hdca[c]"]
[{"$nulls":3},"TTDCAt2","h[e] + ttdca[e] --> h[c] + ttdca[c]"]
[{"$nulls":3},"FE2abc","atp[c] + fe2[e] + h2o[c] --> adp[c] + fe2[c] + h[c] + pi[c]"]
[{"$nulls":3},"FORt","for[e] <==> for[c]"]
[{"$nulls":3},"FUCt","fuc-L[e] + h[e] <==> fuc-L[c] + h[c]"]
[{"$nulls":3},"ABUTt2","4abut[e] + h[e] --> 4abut[c] + h[c]"]
[{"$nulls":3},"GALt2","gal[e] + h[e] --> gal[c] + h[c]"]
[{"$nulls":3},"GLCt2","glc-D[e] + h[e] --> glc-D[c] + h[c]"]
[{"$nulls":3},"GALTpts","galt[e] + pep[c] --> galt1p[c] + pyr[c]"]
[{"$nulls":3},"GLNabc","atp[c] + gln-L[e] + h2o[c] --> adp[c] + gln-L[c] + h[c] + pi[c]"]
[{"$nulls":3},"GLYCt","glyc[c] <==> glyc[e]"]
[{"$nulls":3},"GLYALDt","glyald[e] <==> glyald[c]"]
[{"$nulls":3},"UREAt","urea[e] <==> urea[c]"]
[{"$nulls":3},"GLYC3Pt6","glyc3p[e] + pi[c] --> glyc3p[c] + pi[e]"]
[{"$nulls":3},"ASPabc","asp-L[e] + atp[c] + h2o[c] --> adp[c] + asp-L[c] + h[c] + pi[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"GLUabc","atp[c] + glu-L[e] + h2o[c] --> adp[c] + glu-L[c] + h[c] + pi[c]",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"ASPt2","asp-L[e] + h[e] --> asp-L[c] + h[c]"]
[{"$nulls":3},"GLUt2r","glu-L[e] + h[e] <==> glu-L[c] + h[c]"]
[{"$nulls":3},"GLUt4","glu-L[e] + na1[e] --> glu-L[c] + na1[c]"]
[{"$nulls":3},"ORNabc","atp[c] + h2o[c] + orn[e] --> adp[c] + h[c] + orn[c] + pi[c]",{"$nulls":6},1,null,1]
[{"$nulls":3},"ARGabc","arg-L[e] + atp[c] + h2o[c] --> adp[c] + arg-L[c] + h[c] + pi[c]"]
[{"$nulls":3},"HISabc","atp[c] + h2o[c] + his-L[e] --> adp[c] + h[c] + his-L[c] + pi[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"LYSabc","atp[c] + h2o[c] + lys-L[e] --> adp[c] + h[c] + lys-L[c] + pi[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"IDONt2r","h[e] + idon-L[e] <==> h[c] + idon-L[c]"]
[{"$nulls":3},"GLCNt2r","glcn[e] + h[e] <==> glcn[c] + h[c]"]
[{"$nulls":3},"DDGLCNt2r","2ddglcn[e] + h[e] <==> 2ddglcn[c] + h[c]"]
[{"$nulls":3},"Kabc","atp[c] + h2o[c] + k[e] --> adp[c] + h[c] + k[c] + pi[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"AKGt2r","akg[e] + h[e] <==> akg[c] + h[c]"]
[{"$nulls":3},"LCTSt","h[e] + lcts[e] <==> h[c] + lcts[c]"]
[{"$nulls":3},"ILEabc","atp[c] + h2o[c] + ile-L[e] --> adp[c] + h[c] + ile-L[c] + pi[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"THRabc","atp[c] + h2o[c] + thr-L[e] --> adp[c] + h[c] + pi[c] + thr-L[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"ALAabc","ala-L[e] + atp[c] + h2o[c] --> adp[c] + ala-L[c] + h[c] + pi[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"VALabc","atp[c] + h2o[c] + val-L[e] --> adp[c] + h[c] + pi[c] + val-L[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"LEUabc","atp[c] + h2o[c] + leu-L[e] --> adp[c] + h[c] + leu-L[c] + pi[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"D-LACt2","h[e] + lac-D[e] <==> h[c] + lac-D[c]"]
[{"$nulls":3},"GLYCLTt2r","glyclt[e] + h[e] <==> glyclt[c] + h[c]"]
[{"$nulls":3},"L-LACt2r","h[e] + lac-L[e] <==> h[c] + lac-L[c]"]
[{"$nulls":3},"LYSt2r","h[e] + lys-L[e] <==> h[c] + lys-L[c]"]
[{"$nulls":3},"MALTPTabc","atp[c] + h2o[c] + maltpt[e] --> adp[c] + h[c] + maltpt[c] + pi[c]"]
[{"$nulls":3},"MALTabc","atp[c] + h2o[c] + malt[e] --> adp[c] + h[c] + malt[c] + pi[c]"]
[{"$nulls":3},"MALTTTRabc","atp[c] + h2o[c] + maltttr[e] --> adp[c] + h[c] + maltttr[c] + pi[c]"]
[{"$nulls":3},"MALTHXabc","atp[c] + h2o[c] + malthx[e] --> adp[c] + h[c] + malthx[c] + pi[c]"]
[{"$nulls":3},"MALTTRabc","atp[c] + h2o[c] + malttr[e] --> adp[c] + h[c] + malttr[c] + pi[c]"]
[{"$nulls":3},"FRUpts2","fru[e] + pep[c] --> f6p[c] + pyr[c]"]
[{"$nulls":3},"MANpts","man[e] + pep[c] --> man6p[c] + pyr[c]"]
[{"$nulls":3},"GAMpts","gam[e] + pep[c] --> gam6p[c] + pyr[c]"]
[{"$nulls":3},"MELIBt2","h[e] + melib[e] --> h[c] + melib[c]"]
[{"$nulls":3},"METabc","atp[c] + h2o[c] + met-L[e] --> adp[c] + h[c] + met-L[c] + pi[c]"]
[{"$nulls":3},"METDabc","atp[c] + h2o[c] + met-D[e] --> adp[c] + h[c] + met-D[c] + pi[c]"]
[{"$nulls":3},"GALabc","atp[c] + gal[e] + h2o[c] --> adp[c] + gal[c] + h[c] + pi[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"INDOLEt2r","h[e] + indole[e] <==> h[c] + indole[c]"]
[{"$nulls":3},"ACNAMt2","acnam[e] + h[e] --> acnam[c] + h[c]"]
[{"$nulls":3},"NO3t7","no2[c] + no3[e] --> no2[e] + no3[c]"]
[{"$nulls":3},"NO2t2r","h[e] + no2[e] <==> h[c] + no2[c]"]
[{"$nulls":3},"NAt3_2","(2) h[e] + na1[c] --> (2) h[c] + na1[e]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"NAt3_1.5","(3) h[e] + (2) na1[c] --> (3) h[c] + (2) na1[e]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"GSNt2","gsn[e] + h[e] --> gsn[c] + h[c]"]
[{"$nulls":3},"DGSNt2","dgsn[e] + h[e] --> dgsn[c] + h[c]"]
[{"$nulls":3},"DINSt2","din[e] + h[e] --> din[c] + h[c]"]
[{"$nulls":3},"DCYTt2","dcyt[e] + h[e] --> dcyt[c] + h[c]"]
[{"$nulls":3},"DURIt2","duri[e] + h[e] --> duri[c] + h[c]"]
[{"$nulls":3},"DADNt2","dad-2[e] + h[e] --> dad-2[c] + h[c]"]
[{"$nulls":3},"PNTOt4","na1[e] + pnto-R[e] --> na1[c] + pnto-R[c]"]
[{"$nulls":3},"PIt2r","h[e] + pi[e] <==> h[c] + pi[c]"]
[{"$nulls":3},"NMNP","nmn[e] --> nmn[c]"]
[{"$nulls":3},"PTRCabc","atp[c] + h2o[c] + ptrc[e] --> adp[c] + h[c] + pi[c] + ptrc[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"SPMDabc","atp[c] + h2o[c] + spmd[e] --> adp[c] + h[c] + pi[c] + spmd[c]"]
[{"$nulls":3},"PTRCORNt7","orn[c] + ptrc[e] <==> orn[e] + ptrc[c]"]
[{"$nulls":3},"PTRCt2r","h[e] + ptrc[e] <==> h[c] + ptrc[c]"]
[{"$nulls":3},"PROt2r","h[e] + pro-L[e] <==> h[c] + pro-L[c]"]
[{"$nulls":3},"PROabc","atp[c] + h2o[c] + pro-L[e] --> adp[c] + h[c] + pi[c] + pro-L[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"PIabc","atp[c] + h2o[c] + pi[e] --> adp[c] + h[c] + (2) pi[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"ACMANApts","acmana[e] + pep[c] --> acmanap[c] + pyr[c]"]
[{"$nulls":3},"MNLpts","mnl[e] + pep[c] --> mnl1p[c] + pyr[c]"]
[{"$nulls":3},"SUCpts","pep[c] + sucr[e] --> pyr[c] + suc6p[c]"]
[{"$nulls":3},"GLCpts","glc-D[e] + pep[c] --> g6p[c] + pyr[c]"]
[{"$nulls":3},"FRUpts","fru[e] + pep[c] --> f1p[c] + pyr[c]"]
[{"$nulls":3},"TREpts","pep[c] + tre[e] --> pyr[c] + tre6p[c]"]
[{"$nulls":3},"PROt4","na1[e] + pro-L[e] --> na1[c] + pro-L[c]"]
[{"$nulls":3},"RMNt","h[e] + rmn[e] --> h[c] + rmn[c]"]
[{"$nulls":3},"TSULabc","atp[c] + h2o[c] + tsul[e] --> adp[c] + h[c] + pi[c] + tsul[c]"]
[{"$nulls":3},"SERt2r","h[e] + ser-L[e] <==> h[c] + ser-L[c]"]
[{"$nulls":3},"THMabc","atp[c] + h2o[c] + thm[e] --> adp[c] + h[c] + pi[c] + thm[c]"]
[{"$nulls":3},"SBTpts","pep[c] + sbt-D[e] --> pyr[c] + sbt6p[c]"]
[{"$nulls":3},"SERt4","na1[e] + ser-L[e] --> na1[c] + ser-L[c]"]
[{"$nulls":3},"THRt4","na1[e] + thr-L[e] --> na1[c] + thr-L[c]"]
[{"$nulls":3},"TAURabc","atp[c] + h2o[c] + taur[e] --> adp[c] + h[c] + pi[c] + taur[c]"]
[{"$nulls":3},"THRt2r","h[e] + thr-L[e] <==> h[c] + thr-L[c]"]
[{"$nulls":3},"TRPt2r","h[e] + trp-L[e] <==> h[c] + trp-L[c]"]
[{"$nulls":3},"Kt2r","h[e] + k[e] <==> h[c] + k[c]"]
[{"$nulls":3},"TYRt2r","h[e] + tyr-L[e] <==> h[c] + tyr-L[c]"]
[{"$nulls":3},"GLYC3Pabc","atp[c] + glyc3p[e] + h2o[c] --> adp[c] + glyc3p[c] + h[c] + pi[c]",{"$nulls":5},1,null,null,1]
[{"$nulls":3},"MAN6Pt6_2","man6p[e] + (2) pi[c] --> man6p[c] + (2) pi[e]"]
[{"$nulls":3},"G6Pt6_2","g6p[e] + (2) pi[c] --> g6p[c] + (2) pi[e]"]
[{"$nulls":3},"FUCPt6_2","fuc1p-L[e] + (2) pi[c] --> fuc1p-L[c] + (2) pi[e]"]
[{"$nulls":3},"XTSNt2r","h[e] + xtsn[e] <==> h[c] + xtsn[c]"]
[{"$nulls":3},"INSt2r","h[e] + ins[e] <==> h[c] + ins[c]"]
[{"$nulls":3},"ADNt2r","adn[e] + h[e] <==> adn[c] + h[c]"]
[{"$nulls":3},"CYTDt2r","cytd[e] + h[e] <==> cytd[c] + h[c]"]
[{"$nulls":3},"THMDt2r","h[e] + thymd[e] <==> h[c] + thymd[c]"]
[{"$nulls":3},"URIt2r","h[e] + uri[e] <==> h[c] + uri[c]"]
[{"$nulls":3},"XYLt2","h[e] + xyl-D[e] --> h[c] + xyl-D[c]"]
[{"$nulls":3},"XYLabc","atp[c] + h2o[c] + xyl-D[e] --> adp[c] + h[c] + pi[c] + xyl-D[c]",{"$nulls":4},1,{"$nulls":3},1]
[{"$nulls":3},"CHLt2r","chol[e] + h[e] <==> chol[c] + h[c]"]
[{"$nulls":3},"ADEt2r","ade[e] + h[e] <==> ade[c] + h[c]"]
[{"$nulls":3},"RIBabc","atp[c] + h2o[c] + rib-D[e] --> adp[c] + h[c] + pi[c] + rib-D[c]"]
[{"$nulls":3},"PSCVT","[c]pep + skm5p <==> 3psme + pi"]
[{"$nulls":3},"DHQS","[c]2dda7p --> 3dhq + pi",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"CHORS","[c]3psme --> chor + pi"]
[{"$nulls":3},"DHQD","[c]3dhq <==> 3dhsk + h2o",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"SHK3Dr","[c]3dhsk + h + nadph <==> nadp + skm",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"DDPA","[c]e4p + h2o + pep --> 2dda7p + pi",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"SHKK","[c]atp + skm --> adp + h + skm5p"]
[{"$nulls":3},"PPNDH","[c]h + pphn --> co2tot + phpyr"]
[{"$nulls":3},"CHORM","[c]chor --> pphn"]
[{"$nulls":3},"TRPAS2","[c]h2o + trp-L <==> indole + nh4 + pyr",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"TRPS2","[c]indole + ser-L --> h2o + trp-L",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"TRPS3","[c]3ig3p --> g3p + indole"]
[{"$nulls":3},"TRPS1","[c]3ig3p + ser-L --> g3p + h2o + trp-L"]
[{"$nulls":3},"PRAIi","[c]pran --> 2cpr5p"]
[{"$nulls":3},"IGPS","[c]2cpr5p + h --> 3ig3p + co2tot"]
[{"$nulls":3},"ANS","[c]chor + gln-L --> anth + glu-L + h + pyr"]
[{"$nulls":3},"ANPRT","[c]anth + prpp --> ppi + pran"]
[{"$nulls":3},"PPND","[c]nad + pphn + h2o --> 34hpp + co2tot + nadh"]
[{"$nulls":3},"TYRTA","[c]akg + tyr-L <==> 34hpp + glu-L"]
[{"$nulls":3},"PHETA1","[c]akg + phe-L <==> glu-L + phpyr"]
[{"$nulls":3},"BETALDHx","[c]betald + h2o + nad --> glyb + (2) h + nadh"]
[{"$nulls":3},"BETALDHy","[c]betald + h2o + nadp --> glyb + (2) h + nadph"]
[{"$nulls":3},"HCO3E","[c]co2tot <==> h + hco3"]
[{"$nulls":3},"CYANST","[c]cyan + tsul --> h + so3 + tcynt"]
[{"$nulls":3},"CAT","[c](2) h2o2 --> (2) h2o + o2",null,null,1,{"$nulls":5},1]
[{"$nulls":3},"SELNPS","[c]atp + h2o + seln --> amp + pi + selnp"]
[{"$nulls":3},"SPODM","[c](2) h + (2) o2- --> h2o2 + o2"]
[{"$nulls":3},"ACONMT","[c]acon-T + amet --> aconm + ahcys"]
[{"$nulls":3},"THRD_L","[c]thr-L --> 2obut + nh4"]
[{"$nulls":3},"ACHBS","[c]2obut + h + pyr + h2o --> 2ahbut + co2tot"]
[{"$nulls":3},"ACLS","[c]h + (2) pyr + h2o --> alac-S + co2tot"]
[{"$nulls":3},"KARA2i","[c]2ahbut + h + nadph --> 23dhmp + nadp"]
[{"$nulls":3},"KARA1i","[c]alac-S + h + nadph --> 23dhmb + nadp"]
[{"$nulls":3},"DHAD2","[c]23dhmp --> 3mop + h2o"]
[{"$nulls":3},"DHAD1","[c]23dhmb --> 3mob + h2o"]
[{"$nulls":3},"ILETA","[c]akg + ile-L <==> 3mop + glu-L"]
[{"$nulls":3},"VALTA","[c]akg + val-L <==> 3mob + glu-L"]
[{"$nulls":3},"LEUTAi","[c]4mop + glu-L --> akg + leu-L",null,null,0,{"$nulls":5},0]
[{"$nulls":3},"IPPS","[c]3mob + accoa + h2o --> 3c3hmp + coa + h"]
[{"$nulls":3},"IPMD","[c]3c2hmp + nad --> 3c4mop + h + nadh"]
[{"$nulls":3},"OMCDC","[c]3c4mop + h + h2o --> 4mop + co2tot"]
[{"$nulls":3},"IPPMIa","[c]3c2hmp <==> 2ippm + h2o"]
[{"$nulls":3},"IPPMIb","[c]2ippm + h2o <==> 3c3hmp"]
[]
[{"$nulls":3},"number of assignments",null,43,null,43,null,42,21,21,null,156]

{"sheet":"additional manual assignments","index":2,"n_rows":62,"n_cols":18,"rows_kept":62,"flags":["formulas_cached_only"]}
[{"$nulls":7},"A: standard assignment procedure",{"$nulls":7},"B: standard assignment with the consideration of the final electron acceptors"]
[]
[{"$nulls":7},"reaction","reaction equation with original reaction directions","note",{"$nulls":5},"reaction","equation","note"]
[{"$nulls":7},"GLYCTO2","[c]glyclt + q8 --> glx + q8h2","quinone pool reductions",{"$nulls":5},"THD2","(2) h[e] + nadh[c] + nadp[c] --> (2) h[c] + nad[c] + nadph[c]","transporters"]
[{"$nulls":7},"GLYCTO3","[c]glyclt + mqn8 --> glx + mql8","quinone pool reductions",{"$nulls":5},"FUMt2_2","fum[e] + (2) h[e] --> fum[c] + (2) h[c]","transporters"]
[{"$nulls":7},"FRD2","[c]fum + mql8 --> mqn8 + succ","quinone pool reductions",{"$nulls":5},"SUCCt2_2","(2) h[e] + succ[e] --> (2) h[c] + succ[c]","transporters"]
[{"$nulls":7},"MDH2","[c]mal-L + q8 --> oaa + q8h2","quinone pool reductions",{"$nulls":5},"SUCCt2_3","(3) h[e] + succ[e] --> (3) h[c] + succ[c]","transporters"]
[{"$nulls":7},"MDH3","[c]mal-L + mqn8 --> mql8 + oaa","quinone pool reductions",{"$nulls":5},"GLCt2","glc-D[e] + h[e] --> glc-D[c] + h[c]","transporters"]
[{"$nulls":7},"ASPO3","[c]asp-L + q8 --> iasp + q8h2","quinone pool reductions",{"$nulls":5},"ARGabc","arg-L[e] + atp[c] + h2o[c] --> adp[c] + arg-L[c] + h[c] + pi[c]","transporters"]
[{"$nulls":7},"L-LACD3","[c]lac-L + mqn8 --> mql8 + pyr","quinone pool reductions",{"$nulls":5},"GLCpts","glc-D[e] + pep[c] --> g6p[c] + pyr[c]","transporters"]
[{"$nulls":7},"LDH_D2","[c]lac-D + q8 --> pyr + q8h2","quinone pool reductions",{"$nulls":5},"TREpts","pep[c] + tre[e] --> pyr[c] + tre6p[c]","transporters"]
[{"$nulls":7},"G3PD7","[c]2dmmq8 + glyc3p --> 2dmmql8 + dhap","quinone pool reductions",{"$nulls":5},"GLYK","[c]atp + glyc --> adp + glyc3p + h","NTP production"]
[{"$nulls":7},"G3PD6","[c]glyc3p + mqn8 --> dhap + mql8","quinone pool reductions",{"$nulls":5},"PPCK","[c]atp + oaa --> adp + co2 + pep","NTP production"]
[{"$nulls":7},"G3PD5","[c]glyc3p + q8 --> dhap + q8h2","quinone pool reductions",{"$nulls":5},"CBPS","[c](2) atp + gln-L + h2o + hco3 --> (2) adp + cbp + glu-L + (2) h + pi","NTP production"]
[{"$nulls":7},"NADH8","2dmmq8[c] + (3.8) h[c] + nadh[c] --> 2dmmql8[c] + (2.8) h[e] + nad[c]","quinone pool reductions",{"$nulls":5},"GLNS","[c]atp + glu-L + nh4 --> adp + gln-L + h + pi","NTP production"]
[{"$nulls":7},"SUCD4","[c]fadh2 + q8 <==> fad + q8h2","quinone pool reductions",{"$nulls":5},"HEX1","[c]atp + glc-D --> adp + g6p + h","NTP production"]
[{"$nulls":7},"DHORD2","[c]dhor-S + q8 --> orot + q8h2","quinone pool reductions",{"$nulls":5},"PPS","[c]atp + h2o + pyr --> amp + (2) h + pep + pi","NTP production"]
[{"$nulls":7},"DHORD5","[c]dhor-S + mqn8 --> mql8 + orot","quinone pool reductions",{"$nulls":5},"INSK","[c]atp + ins --> adp + h + imp","NTP production"]
[{"$nulls":7},"THD2","(2) h[e] + nadh[c] + nadp[c] --> (2) h[c] + nad[c] + nadph[c]","transporters",{"$nulls":5},"NTPP4","[c]ctp + h2o --> cmp + h + ppi","NTP production"]
[{"$nulls":7},"DMSOR2e","2dmmql8[c] + dmso[e] --> 2dmmq8[c] + dms[e] + h2o[e]","transporters",{"$nulls":5},"NTPP8","[c]h2o + utp --> h + ppi + ump","NTP production"]
[{"$nulls":7},"FUMt2_2","fum[e] + (2) h[e] --> fum[c] + (2) h[c]","transporters",{"$nulls":5},"NTPP2","[c]gtp + h2o --> gmp + h + ppi","NTP production"]
[{"$nulls":7},"SUCCt2_2","(2) h[e] + succ[e] --> (2) h[c] + succ[c]","transporters",{"$nulls":5},"NTPP3","[c]dctp + h2o --> dcmp + h + ppi","NTP production"]
[{"$nulls":7},"SUCCt2_3","(3) h[e] + succ[e] --> (3) h[c] + succ[c]","transporters",{"$nulls":5},"NTPP1","[c]dgtp + h2o --> dgmp + h + ppi","NTP production"]
[{"$nulls":7},"GLCt2","glc-D[e] + h[e] --> glc-D[c] + h[c]","transporters",{"$nulls":5},"TRDR","[c]h + nadph + trdox --> nadp + trdrd","NADH/NADPH production"]
[{"$nulls":7},"ARGabc","arg-L[e] + atp[c] + h2o[c] --> adp[c] + arg-L[c] + h[c] + pi[c]","transporters",{"$nulls":5},"GMPR","[c]gmp + (2) h + nadph --> imp + nadp + nh4","NADH/NADPH production"]
[{"$nulls":7},"GLCpts","glc-D[e] + pep[c] --> g6p[c] + pyr[c]","transporters",{"$nulls":5},"P5CR","[c]1pyr5c + (2) h + nadph --> nadp + pro-L","NADH/NADPH production"]
[{"$nulls":7},"TREpts","pep[c] + tre[e] --> pyr[c] + tre6p[c]","transporters",{"$nulls":5},"GLYCLTDx","[c]glx + h + nadh --> glyclt + nad","NADH/NADPH production"]
[{"$nulls":7},"GLYK","[c]atp + glyc --> adp + glyc3p + h","NTP production",{"$nulls":5},"PYAM5PO","[c]h2o + o2 + pyam5p --> h2o2 + nh4 + pydx5p","O2 production"]
[{"$nulls":7},"PPCK","[c]atp + oaa --> adp + co2 + pep","NTP production",{"$nulls":5},"DKMPPD2","[c]dkmpp + (3) h2o --> 2kmb + for + (6) h + pi","CO2 (or formate) consumption"]
[{"$nulls":7},"CBPS","[c](2) atp + gln-L + h2o + hco3 --> (2) adp + cbp + glu-L + (2) h + pi","NTP production",{"$nulls":5},"TEST_AKGDH","[c]akg + coa + nad --> co2 + nadh + succoa","CO2 (or formate) consumption"]
[{"$nulls":7},"GLNS","[c]atp + glu-L + nh4 --> adp + gln-L + h + pi","NTP production",{"$nulls":5},"PDH","[c]coa + nad + pyr --> accoa + co2 + nadh","CO2 (or formate) consumption"]
[{"$nulls":7},"HEX1","[c]atp + glc-D --> adp + g6p + h","NTP production",{"$nulls":5},"PFL","[c]coa + pyr --> accoa + for","CO2 (or formate) consumption"]
[{"$nulls":7},"PPS","[c]atp + h2o + pyr --> amp + (2) h + pep + pi","NTP production",{"$nulls":5},"ADPT","[c]ade + prpp --> amp + ppi","NMP synthesis"]
[{"$nulls":7},"INSK","[c]atp + ins --> adp + h + imp","NTP production",{"$nulls":5},"DUTPDP","[c]dutp + h2o --> dump + h + ppi","NMP synthesis"]
[{"$nulls":7},"GMPS2","[c]atp + gln-L + h2o + xmp --> amp + glu-L + gmp + (2) h + ppi","NTP production",{"$nulls":5},"XPPT","[c]prpp + xan --> ppi + xmp","NMP synthesis"]
[{"$nulls":7},"GART","[c]atp + for + gar --> adp + fgam + h + pi","NTP production",{"$nulls":5},"HXPRT","[c]hxan + prpp --> imp + ppi","NMP synthesis"]
[{"$nulls":7},"NTPP3","[c]dctp + h2o --> dcmp + h + ppi","NTP production",{"$nulls":5},"GUAPRT","[c]gua + prpp --> gmp + ppi","NMP synthesis"]
[{"$nulls":7},"NTPP1","[c]dgtp + h2o --> dgmp + h + ppi","NTP production",{"$nulls":5},"NTPP7","[c]dttp + h2o --> dtmp + h + ppi","NMP synthesis"]
[{"$nulls":7},"NTPP4","[c]ctp + h2o --> cmp + h + ppi","NTP production",{"$nulls":5},"UPPRT","[c]prpp + ura --> ppi + ump","NMP synthesis"]
[{"$nulls":7},"NTPP8","[c]h2o + utp --> h + ppi + ump","NTP production",{"$nulls":5},"DAAD","[c]ala-D + fad + h2o --> fadh2 + nh4 + pyr","other"]
[{"$nulls":7},"NTPP2","[c]gtp + h2o --> gmp + h + ppi","NTP production",{"$nulls":5},"PSP_L","[c]h2o + pser-L --> pi + ser-L","other"]
[{"$nulls":7},"GLYCLTDx","[c]glx + h + nadh --> glyclt + nad","NADH/NADPH production",{"$nulls":5},"MGSA","[c]dhap --> mthgxl + pi","other"]
[{"$nulls":7},"P5CR","[c]1pyr5c + (2) h + nadph --> nadp + pro-L","NADH/NADPH production"]
[{"$nulls":7},"GLYCLTDy","[c]glx + h + nadph --> glyclt + nadp","NADH/NADPH production"]
[{"$nulls":7},"TRDR","[c]h + nadph + trdox --> nadp + trdrd","NADH/NADPH production"]
[{"$nulls":7},"GMPR","[c]gmp + (2) h + nadph --> imp + nadp + nh4","NADH/NADPH production"]
[{"$nulls":7},"ASPO6","[c]asp-L + o2 --> h2o2 + iasp","O2 production"]
[{"$nulls":7},"PYAM5PO","[c]h2o + o2 + pyam5p --> h2o2 + nh4 + pydx5p","O2 production"]
[{"$nulls":7},"DKMPPD2","[c]dkmpp + (3) h2o --> 2kmb + for + (6) h + pi","CO2 (or formate) consumption"]
[{"$nulls":7},"TEST_AKGDH","[c]akg + coa + nad --> co2 + nadh + succoa","CO2 (or formate) consumption"]
[{"$nulls":7},"PDH","[c]coa + nad + pyr --> accoa + co2 + nadh","CO2 (or formate) consumption"]
[{"$nulls":7},"PFL","[c]coa + pyr --> accoa + for","CO2 (or formate) consumption"]
[{"$nulls":7},"ADPT","[c]ade + prpp --> amp + ppi","NMP synthesis"]
[{"$nulls":7},"DUTPDP","[c]dutp + h2o --> dump + h + ppi","NMP synthesis"]
[{"$nulls":7},"XPPT","[c]prpp + xan --> ppi + xmp","NMP synthesis"]
[{"$nulls":7},"HXPRT","[c]hxan + prpp --> imp + ppi","NMP synthesis"]
[{"$nulls":7},"GUAPRT","[c]gua + prpp --> gmp + ppi","NMP synthesis"]
[{"$nulls":7},"NTPP7","[c]dttp + h2o --> dtmp + h + ppi","NMP synthesis"]
[{"$nulls":7},"UPPRT","[c]prpp + ura --> ppi + ump","NMP synthesis"]
[{"$nulls":7},"DAAD","[c]ala-D + fad + h2o --> fadh2 + nh4 + pyr","other"]
[{"$nulls":7},"PSP_L","[c]h2o + pser-L --> pi + ser-L","other"]
[{"$nulls":7},"MGSA","[c]dhap --> mthgxl + pi","other"]

{"sheet":"model","index":3,"n_rows":925,"n_cols":4,"rows_kept":925,"flags":["formulas_cached_only"]}
[]
[]
[]
[null,"reaction","reaction equation"]
[null,"ALATA_L","[c]akg + ala-L <==> glu-L + pyr"]
[null,"ALAR","[c]ala-L <==> ala-D"]
[null,"ASNN","[c]asn-L + h2o --> asp-L + nh4"]
[null,"ASNS2","[c]asp-L + atp + nh4 --> amp + asn-L + h + ppi"]
[null,"ASNS1","[c]asp-L + atp + gln-L + h2o --> amp + asn-L + glu-L + h + ppi"]
[null,"ASPT","[c]asp-L --> fum + nh4"]
[null,"ASPTA","[c]akg + asp-L <==> glu-L + oaa"]
[null,"VPAMT","[c]3mob + ala-L --> pyr + val-L"]
[null,"DAAD","[c]ala-D + fad + h2o --> fadh2 + nh4 + pyr"]
[null,"FFSD","[c]h2o + suc6p --> fru + g6p"]
[null,"A5PISO","[c]ru5p-D <==> ara5p"]
[null,"MME","[c]mmcoa-R <==> mmcoa-S"]
[null,"MICITD","[c]2mcacn + h2o --> micit"]
[null,"ALCD19","[c]glyald + h + nadh <==> glyc + nad"]
[null,"TGBPA","[c]tagdp-D <==> dhap + g3p"]
[null,"LCAD","[c]h2o + lald-L + nad <==> (2) h + lac-L + nadh"]
[null,"ALDD2x","[c]acald + h2o + nad --> ac + (2) h + nadh"]
[null,"ARAI","[c]arab-L <==> rbl-L"]
[null,"RBK_L1","[c]atp + rbl-L --> adp + h + ru5p-L"]
[null,"RBP4E","[c]ru5p-L <==> xu5p-D"]
[null,"ACACCT","[c]acac + accoa --> aacoa + ac"]
[null,"BUTCT","[c]accoa + but --> ac + btcoa"]
[null,"AB6PGH","[c]arbt6p + h2o --> g6p + hqn"]
[null,"PMANM","[c]man1p <==> man6p"]
[null,"PPM2","[c]2dr1p <==> 2dr5p"]
[null,"PPM","[c]r1p <==> r5p"]
[null,"DRPA","[c]2dr5p --> acald + g3p"]
[null,"GALCTND","[c]galctn-D --> 2dh3dgal + h2o"]
[null,"DDPGALA","[c]2dh3dgal6p <==> g3p + pyr"]
[null,"DDGALK","[c]2dh3dgal + atp --> 2dh3dgal6p + adp + h"]
[null,"DHAPT","[c]dha + pep --> dhap + pyr"]
[null,"FAO4","[c]btcoa + fad + h2o + nad --> aacoa + fadh2 + h + nadh"]
[null,"ALDD19x","[c]h2o + nad + pacald --> (2) h + nadh + pac"]
[null,"FRUK","[c]atp + f1p --> adp + fdp + h"]
[null,"FCLPA","[c]fc1p <==> dhap + lald-L"]
[null,"FCI","[c]fuc-L <==> fcl-L"]
[null,"FCLK","[c]atp + fcl-L --> adp + fc1p + h"]
[null,"LCAR","[c]h + lald-L + nadh <==> 12ppd-S + nad"]
[null,"UDPG4E","[c]udpg <==> udpgal"]
[null,"GALKr","[c]atp + gal <==> adp + gal1p + h"]
[null,"UGLT","[c]gal1p + udpg <==> g1p + udpgal"]
[null,"GALU","[c]g1p + h + utp <==> ppi + udpg"]
[null,"GALCTD","[c]galct-D --> 5dh4dglc + h2o"]
[null,"GLTPD","[c]galt1p + nad <==> h + nadh + tag6p-D"]
[null,"GLYCTO2","[c]glyclt + q8 --> glx + q8h2"]
[null,"GLYCTO3","[c]glyclt + mqn8 --> glx + mql8"]
[null,"GLYCTO4","[c]2dmmq8 + glyclt --> 2dmmql8 + glx"]
[null,"GLYCDx","[c]glyc + nad --> dha + h + nadh"]
[null,"GLYK","[c]atp + glyc --> adp + glyc3p + h"]
[null,"PGLYCP","[c]2pglyc + h2o --> glyclt + pi"]
[null,"G3PD2","[c]glyc3p + nadp <==> dhap + h + nadph"]
[null,"GLCRAL","[c]5dh4dglc --> 2h3oppan + pyr"]
[null,"DHPPD","[c]cechddd + nad --> dhpppn + h + nadh"]
[null,"DHCIND","[c]cenchddd + nad --> dhcinnm + h + nadh"]
[null,"PPPNDO","[c]h + nadh + o2 + pppn --> cechddd + nad"]
[null,"CINNDO","[c]cinnm + h + nadh + o2 --> cenchddd + nad"]
[null,"HPYRI","[c]hpyr <==> 2h3oppan"]
[null,"IDOND","[c]5dglcn + h + nadh <==> idon-L + nad"]
[null,"IDOND2","[c]5dglcn + h + nadph --> idon-L + nadp"]
[null,"GNK","[c]atp + glcn --> 6pgc + adp + h"]
[null,"5DGLCNR","[c]5dglcn + h + nadph <==> glcn + nadp"]
[null,"DDGLK","[c]2ddglcn + atp --> 2ddg6p + adp + h"]
[null,"LACZ","[c]h2o + lcts --> gal + glc-D"]
[null,"MLTP1","[c]maltpt + pi <==> g1p + maltttr"]
[null,"MLTP2","[c]malthx + pi <==> g1p + maltpt"]
[null,"MLTP3","[c]malthp + pi <==> g1p + malthx"]
[null,"AMALT1","[c]malt + malttr --> glc-D + maltttr"]
[null,"AMALT2","[c]malt + maltttr --> glc-D + maltpt"]
[null,"AMALT3","[c]malt + maltpt --> glc-D + malthx"]
[null,"AMALT4","[c]malt + malthx --> glc-D + malthp"]
[null,"MLTG1","[c]h2o + malttr --> glc-D + malt"]
[null,"MLTG2","[c]h2o + maltttr --> glc-D + malttr"]
[null,"MLTG3","[c]h2o + maltpt --> glc-D + maltttr"]
[null,"MLTG4","[c]h2o + malthx --> glc-D + maltpt"]
[null,"MLTG5","[c]h2o + malthp --> glc-D + malthx"]
[null,"MAN6PI","[c]man6p <==> f6p"]
[null,"GALS3","[c]h2o + melib --> gal + glc-D"]
[null,"3HCINNMH","[c]3hcinnm + h + nadh + o2 --> dhcinnm + h2o + nad"]
[null,"3HPPPNH","[c]3hpppn + h + nadh + o2 --> dhpppn + h2o + nad"]
[null,"DHCINDO","[c]dhcinnm + o2 --> hkntd"]
[null,"HPPPNDO","[c]dhpppn + o2 --> hkndd"]
[null,"HKNDDH","[c]h2o + hkndd --> (2) h + op4en + succ"]
[null,"HKNTDH","[c]h2o + hkntd --> fum + (2) h + op4en"]
[null,"OP4ENH","[c]h2o + op4en --> 4h2opntn"]
[null,"HOPNTAL","[c]4h2opntn --> acald + pyr"]
[null,"ACALDi","[c]acald + coa + nad --> accoa + h + nadh"]
[null,"M1PD","[c]mnl1p + nad <==> f6p + h + nadh"]
[null,"AGDC","[c]acgam6p + h2o --> ac + gam6p"]
[null,"G6PDA","[c]gam6p + h2o --> f6p + nh4"]
[null,"ACNML","[c]acnam --> acmana + pyr"]
[null,"TRE6PS","[c]g6p + udpg --> h + tre6p + udp"]
[null,"TRE6PP","[c]h2o + tre6p --> pi + tre"]
[null,"PACCOAL","[c]atp + coa + pac --> amp + phaccoa + ppi"]
[null,"PFK_2","[c]atp + tag6p-D --> adp + h + tagdp-D"]
[null,"PGMT","[c]g1p <==> g6p"]
[null,"MCITL2","[c]micit <==> pyr + succ"]
[null,"MCITS","[c]h2o + oaa + ppcoa --> 2mcit + coa + h"]
[null,"MCITD","[c]2mcit --> 2mcacn + h2o"]
[null,"ACCOAL","[c]atp + coa + ppa --> adp + pi + ppcoa"]
[null,"PTA2","[c]pi + ppcoa --> coa + ppap"]
[null,"RBK","[c]atp + rib-D --> adp + h + r5p"]
[null,"RMI","[c]rmn <==> rml"]
[null,"RMK","[c]atp + rml --> adp + h + rml1p"]
[null,"RMPA","[c]rml1p <==> dhap + lald-L"]
[null,"MMM2","[c]succoa --> mmcoa-R"]
[null,"KG6PDC","[c]3dgulnp + h + h2o --> co2tot + xu5p-L"]
[null,"X5PL3E","[c]xu5p-L --> ru5p-L"]
[null,"SBTPD","[c]nad + sbt6p <==> f6p + h + nadh"]
[null,"TAUDO","[c]akg + o2 + taur + h2o --> aacald + co2tot + h + so3 + succ"]
[null,"PPAKr","[c]adp + ppap <==> atp + ppa"]
[null,"OBTFL","[c]2obut + coa --> for + ppcoa"]
[null,"TREHe","[e]h2o + tre --> (2) glc-D"]
[null,"TRE6PH","[c]h2o + tre6p --> g6p + glc-D"]
[null,"TREH","[c]h2o + tre --> (2) glc-D"]
[null,"TARTD","[c]tartr-L --> h2o + oaa"]
[null,"PEAMNO","[c]h2o + o2 + peamn --> h2o2 + nh4 + pacald"]
[null,"ALTRH","[c]altrn --> 2ddglcn + h2o"]
[null,"TAGURr","[c]altrn + nad <==> h + nadh + tagur"]
[null,"GUI1","[c]glcur <==> fruur"]
[null,"GUI2","[c]galur <==> tagur"]
[null,"MNNH","[c]mana --> 2ddglcn + h2o"]
[null,"MANAO","[c]mana + nad <==> fruur + h + nadh"]
[null,"XYLI2i","[c]fru --> glc-D"]
[null,"XYLI1","[c]xyl-D <==> xylu-D"]
[null,"XYLK","[c]atp + xylu-D --> adp + h + xu5p-D"]
[null,"DKGLCNR1","[c]25dkglcn + h + nadph --> 2dhguln + nadp"]
[null,"HPYRRx","[c]h + hpyr + nadh --> glyc-R + nad"]
[null,"HPYRRy","[c]h + hpyr + nadph --> glyc-R + nadp"]
[null,"GLCRD","[c]glcr --> 5dh4dglc + h2o"]
[null,"MMCD","[c]h + mmcoa-S + h2o --> co2tot + ppcoa"]
[null,"PPCSCT","[c]ppcoa + succ --> ppa + succoa"]
[null,"DKGLCNR2y","[c]25dkglcn + h + nadph --> 5dglcn + nadp"]
[null,"2DGLCNRx","[c]2dhglcn + h + nadh --> glcn + nad"]
[null,"2DGLCNRy","[c]2dhglcn + h + nadph --> glcn + nadp"]
[null,"DKGLCNR2x","[c]25dkglcn + h + nadh --> 5dglcn + nad"]
[null,"2DGULRx","[c]2dhguln + h + nadh --> idon-L + nad"]
[null,"2DGULRy","[c]2dhguln + h + nadph --> idon-L + nadp"]
[null,"DOGULNR","[c]23doguln + h + nadh --> 3dhguln + nad"]
[null,"ICL","[c]icit --> glx + succ"]
[null,"MALS","[c]accoa + glx + h2o --> coa + h + mal-L"]
[null,"ME2","[c]mal-L + nadp + h2o --> co2tot + nadph + pyr"]
[null,"PPCK","[c]atp + oaa + h2o --> adp + co2tot + pep"]
[null,"PPA","[c]h2o + ppi --> h + (2) pi"]
[null,"PPC","[c]co2tot + pep --> h + oaa + pi"]
[null,"ME1","[c]mal-L + nad + h2o --> co2tot + nadh + pyr"]
[null,"MDRPD","[c]5mdru1p --> dkmpp + h2o"]
[null,"DKMPPD2","[c]dkmpp + (3) h2o --> 2kmb + for + (6) h + pi"]
[null,"PTRCTA","[c]akg + ptrc --> 4abutn + glu-L"]
[null,"SSALx","[c]h2o + nad + sucsal --> (2) h + nadh + succ"]
[null,"ABUTD","[c]4abutn + h2o + nad --> 4abut + (2) h + nadh"]
[null,"MTRK","[c]5mtr + atp --> 5mdr1p + adp + h"]
[null,"MTRI","[c]5mdr1p <==> 5mdru1p"]
[null,"DKMPPD","[c]dkmpp + h2o + o2 --> 2kmb + for + (2) h + pi"]
[null,"G5SADs","[c]glu5sa --> 1pyr5c + h + h2o"]
[null,"UNK3","[c]2kmb + glu-L --> akg + met-L"]
[null,"ACGS","[c]accoa + glu-L --> acglu + coa + h"]
[null,"ACGK","[c]acglu + atp --> acg5p + adp"]
[null,"AGPR","[c]acg5sa + nadp + pi <==> acg5p + h + nadph"]
[null,"ACOTA","[c]acorn + akg <==> acg5sa + glu-L"]
[null,"NACODA","[c]acg5sa + h2o --> ac + glu5sa"]
[null,"ACODA","[c]acorn + h2o --> ac + orn"]
[null,"ARGSS","[c]asp-L + atp + citr-L --> amp + argsuc + h + ppi"]
[null,"ARGSL","[c]argsuc <==> arg-L + fum"]
[null,"OCBT","[c]cbp + orn <==> citr-L + h + pi"]
[null,"AST","[c]arg-L + succoa --> coa + h + sucarg"]
[null,"SOTA","[c]akg + sucorn --> glu-L + sucgsa"]
[null,"SADH","[c](2) h + (3) h2o + sucarg --> co2tot + (2) nh4 + sucorn"]
[null,"SGSAD","[c]h2o + nad + sucgsa --> (2) h + nadh + sucglu"]
[null,"SGDS","[c]h2o + sucglu --> glu-L + succ"]
[null,"CBPS","[c](2) atp + gln-L + h2o + hco3 --> (2) adp + cbp + glu-L + (2) h + pi"]
[null,"SSALy","[c]h2o + nadp + sucsal --> (2) h + nadph + succ"]
[null,"ABTA","[c]4abut + akg --> glu-L + sucsal"]
[null,"GSPMDA","[c]gtspmd + h2o --> gthrd + spmd"]
[null,"GSPMDS","[c]atp + gthrd + spmd --> adp + gtspmd + h + pi"]
[null,"MTAN","[c]5mta + h2o --> 5mtr + ade"]
[null,"G5SD","[c]glu5p + h + nadph --> glu5sa + nadp + pi"]
[null,"GLU5K","[c]atp + glu-L --> adp + glu5p"]
[null,"P5CR","[c]1pyr5c + (2) h + nadph --> nadp + pro-L"]
[null,"P5CD","[c]1pyr5c + (2) h2o + nad --> glu-L + h + nadh"]
[null,"PROD2","[c]fad + pro-L --> 1pyr5c + fadh2 + h"]
[null,"ARGDC","[c]arg-L + h + h2o --> agm + co2tot"]
[null,"AGMT","[c]agm + h2o --> ptrc + urea"]
[null,"ORNDC","[c]h + orn + h2o --> co2tot + ptrc"]
[null,"ADMDCr","[c]amet + h + h2o <==> ametam + co2tot"]
[null,"SPMS","[c]ametam + ptrc --> 5mta + h + spmd"]
[null,"SPMDAT1","[c]accoa + spmd --> N1aspmd + coa + h"]
[null,"SPMDAT2","[c]accoa + spmd --> coa + h + n8aspmd"]
[null,"ORNTA","[c]akg + orn --> glu-L + glu5sa"]
[null,"PPTGS","[c]uaagmda --> h + peptido_EC + udcpdp"]
[null,"UDCPDP","[c]h2o + udcpdp --> h + pi + udcpp"]
[null,"KDOPP","[c]h2o + kdo8p --> kdo + pi"]
[null,"PEPT_EC","[c]cmp + h + (0.02) pe_EC <==> (0.02) 12dgr_EC + cdpea"]
[null,"PAPA_EC","[c]h2o + (0.02) pa_EC --> (0.02) 12dgr_EC + pi"]
[null,"ECAP_EC","[c]unagamuf --> eca_EC + h + udcpdp"]
[null,"AACPS1","[c]ACP + atp + ttdca --> amp + myrsACP + ppi"]
[null,"AACPS2","[c]ACP + atp + ttdcea --> amp + ppi + tdeACP"]
[null,"AACPS3","[c]ACP + atp + hdca --> amp + palmACP + ppi"]
[null,"AACPS4","[c]ACP + atp + hdcea --> amp + hdeACP + ppi"]
[null,"AACPS5","[c]ACP + atp + ocdcea --> amp + octeACP + ppi"]
[null,"ALAALAr","[c](2) ala-D + atp <==> adp + alaala + h + pi"]
[null,"DAGK_EC","[c](0.02) 12dgr_EC + atp --> adp + h + (0.02) pa_EC"]
[null,"ETHAAL","[c]etha --> acald + nh4"]
[null,"GDMANE","[c]gdpddman --> gdpofuc"]
[null,"GOFUCR","[c]gdpofuc + h + nadph --> gdpfuc + nadp"]
[null,"UDPGALM","[c]udpgal --> udpgalfur"]
[null,"GF6PTA","[c]f6p + gln-L --> gam6p + glu-L"]
[null,"UAGDP","[c]acgam1p + h + utp --> ppi + uacgam"]
[null,"G1PACT","[c]accoa + gam1p --> acgam1p + coa + h"]
[null,"GPDDA1","[c]g3pc + h2o --> chol + glyc3p + h"]
[null,"GPDDA2","[c]g3pe + h2o --> etha + glyc3p + h"]
[null,"GPDDA3","[c]g3ps + h2o --> glyc3p + h + ser-L"]
[null,"GPDDA4","[c]g3pg + h2o --> glyc + glyc3p + h"]
[null,"GPDDA5","[c]g3pi + h2o --> glyc3p + h + inost"]
[null,"GMAND","[c]gdpmann --> gdpddman + h2o"]
[null,"S7PI","[c]s7p --> gmhep7p"]
[null,"GMHEPPA","[c]gmhep17bp + h2o --> gmhep1p + pi"]
[null,"KDOPS","[c]ara5p + h2o + pep --> kdo8p + pi"]
[null,"KDOCT2","[c]ctp + kdo --> ckdo + ppi"]
[null,"MOAT","[c]ckdo + lipidA --> cmp + h + kdolipid4"]
[null,"MOAT2","[c]ckdo + kdolipid4 --> cmp + h + kdo2lipid4"]
[null,"UAGAAT","[c]3hmrsACP + uacgam <==> ACP + u3aga"]
[null,"LPADSS","[c]lipidX + u23ga --> h + lipidAds + udp"]
[null,"UHGADA","[c]h2o + u3aga --> ac + u3hga"]
[null,"U23GAAT","[c]3hmrsACP + u3hga --> ACP + h + u23ga"]
[null,"TDSK","[c]atp + lipidAds --> adp + h + lipidA"]
[null,"EDTXS1","[c]ddcaACP + kdo2lipid4 --> ACP + kdo2lipid4L"]
[null,"EDTXS3","[c]hdeACP + kdo2lipid4 --> ACP + kdo2lipid4p"]
[null,"MAN1PT2","[c]gdp + h + man1p --> gdpmann + pi"]
[null,"PAPPT3","[c]udcpp + ugmda --> uagmda + ump"]
[null,"PGAMT","[c]gam1p <==> gam6p"]
[null,"EDTXS4","[c]kdo2lipid4p + myrsACP --> ACP + lipa_cold"]
[null,"EDTXS2","[c]kdo2lipid4L + myrsACP --> ACP + lipa"]
[null,"UAGCVT","[c]pep + uacgam --> pi + uaccg"]
[null,"UAPGR","[c]h + nadph + uaccg --> nadp + uamr"]
[null,"UAMAS","[c]ala-L + atp + uamr --> adp + h + pi + uama"]
[null,"UAMAGS","[c]atp + glu-D + uama --> adp + h + pi + uamag"]
[null,"UAAGDS","[c]26dap-M + atp + uamag --> adp + h + pi + ugmd"]
[null,"UGMDDS","[c]alaala + atp + ugmd --> adp + h + pi + ugmda"]
[null,"UAGPT3","[c]uacgam + uagmda --> h + uaagmda + udp"]
[null,"GLUR","[c]glu-D <==> glu-L"]
[null,"PLIPA3","[c]h2o + (0.02) pc_EC --> (0.02) agpc_EC + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[null,"PLIPA1","[c]h2o + (0.02) pg_EC --> (0.02) agpg_EC + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[null,"PLIPA2","[c]h2o + (0.02) pe_EC --> (0.02) agpe_EC + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[null,"LPLIPA1","[c](0.02) agpg_EC + h2o --> g3pg + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[null,"LPLIPA2","[c](0.02) agpe_EC + h2o --> g3pe + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[null,"LPLIPA3","[c](0.02) agpc_EC + h2o --> g3pc + h + (0.36) hdca + (0.07) hdcea + (0.5) ocdcea + (0.02) ttdca + (0.05) ttdcea"]
[null,"LPLIPA4","[c](0.02) agpe_EC + (0.02) pg_EC --> (0.02) apg_EC + g3pe"]
[null,"LPLIPA5","[c](0.02) agpc_EC + (0.02) pg_EC --> (0.02) apg_EC + g3pc"]
[null,"LPLIPA6","[c](0.02) agpg_EC + (0.02) pg_EC --> (0.02) apg_EC + g3pg"]
[null,"AGMHE","[c]adphep-D,D --> adphep-L,D"]
[null,"GMHEPAT","[c]atp + gmhep1p + h --> adphep-D,D + ppi"]
[null,"GMHEPK","[c]atp + gmhep7p --> adp + gmhep17bp + h"]
[null,"LPSSYN_EC","[c](3) adphep-L,D + (2) cdpea + (3) ckdo + lipa + (2) udpg --> (3) adp + (2) cdp + (3) cmp + (10) h + lps_EC + (2) udp"]
[null,"G1PTT","[c]dttp + g1p + h --> dtdpglu + ppi"]
[null,"TDPGDH","[c]dtdpglu --> dtdp4d6dg + h2o"]
[null,"TDPDRE","[c]dtdp4d6dg --> dtdp4d6dm"]
[null,"TDPDRR","[c]dtdp4d6dm + h + nadph --> dtdprmn + nadp"]
[null,"MI1PP","[c]h2o + mi1p-D --> inost + pi"]
[null,"UDPGD","[c]h2o + (2) nad + udpg --> (3) h + (2) nadh + udpglcur"]
[null,"USHD","[c]h2o + u23ga --> (2) h + lipidX + ump"]
[null,"ACGAMT","[c]uacgam + udcpp --> ump + unaga"]
[null,"UAG2Ei","[c]uacgam --> uacmam"]
[null,"UACMAMO","[c]h2o + (2) nad + uacmam --> (3) h + (2) nadh + uacmamu"]
[null,"TDPADGAT","[c]accoa + dtdp4addg --> coa + dtdp4aaddg + h"]
[null,"TDPAGTA","[c]dtdp4d6dg + glu-L --> akg + dtdp4addg"]
[null,"AADDGT","[c]dtdp4aaddg + unagamu --> dtdp + h + unagamuf"]
[null,"ACMAMUT","[c]uacmamu + unaga --> h + udp + unagamu"]
[null,"ACONT","[c]cit <==> icit"]
[null,"CITL","[c]cit --> ac + oaa"]
[null,"FRD2","[c]fum + mql8 --> mqn8 + succ"]
[null,"FRD3","[c]2dmmql8 + fum --> 2dmmq8 + succ"]
[null,"FUM","[c]fum + h2o <==> mal-L"]
[null,"CS","[c]accoa + h2o + oaa --> cit + coa + h"]
[null,"ICDHyr","[c]icit + nadp + h2o <==> akg + co2tot + nadph"]
[null,"TEST_AKGDH","[c]akg + coa + nad + h2o --> co2tot + nadh + succoa"]
[null,"MDH","[c]mal-L + nad <==> h + nadh + oaa"]
[null,"MDH2","[c]mal-L + q8 --> oaa + q8h2"]
[null,"MDH3","[c]mal-L + mqn8 --> mql8 + oaa"]
[null,"SUCD1i","[c]fad + succ --> fadh2 + fum"]
[null,"SUCOAS","[c]atp + coa + succ <==> adp + pi + succoa"]
[null,"PMDPHT","[c]5aprbu + h2o --> 4r5au + pi"]
[null,"DNMPPA","[c]dhpmp + h2o --> dhnpt + pi"]
[null,"NADPPPS","[c]h2o + nadp --> nad + pi"]
[null,"NMNN","[c]h2o + nmn --> h + ncam + r5p"]
[null,"NADDPe","[e]h2o + nad --> amp + (2) h + nmn"]
[null,"PPCDC","[c]4ppcys + h +h2o --> co2tot + pan4p"]
[null,"DPCOAK","[c]atp + dpcoa --> adp + coa + h"]
[null,"HYPOE","[c]h2o + pyam5p --> pi + pydam"]
[null,"PYDXPP","[c]h2o + pydx5p --> pi + pydx"]
[null,"PDXPP","[c]h2o + pdx5p --> pi + pydxn"]
[null,"NMNDA","[c]h2o + nmn --> nh4 + nicrnt"]
[null,"TMKr","[c]atp + thm <==> adp + h + thmmp"]
[null,"PPNCL2","[c]4ppan + ctp + cys-L --> 4ppcys + cmp + h + ppi"]
[null,"ACPS1","[c]apoACP + coa --> ACP + h + pap"]
[null,"AMAOTr","[c]8aonn + amet <==> amob + dann"]
[null,"BTS2","[c]cys-L + dtbt <==> ala-L + btn + (2) h"]
[null,"DBTSr","[c]atp + co2tot + dann <==> adp + dtbt + (3) h + pi + h2o"]
[null,"AOXSr","[c]ala-L + h + pmcoa + h2o <==> 8aonn + co2tot + coa"]
[null,"BSORx","[c]btnso + h + nadh --> btn + h2o + nad"]
[null,"BSORy","[c]btnso + h + nadph --> btn + h2o + nadp"]
[null,"CBIAT","[c]atp + cbi + h2o <==> adocbi + pi + ppi"]
[null,"CBLAT","[c]atp + cbl1 + h2o <==> adocbl + pi + ppi"]
[null,"PNTK","[c]atp + pnto-R --> 4ppan + adp + h"]
[null,"PTPATi","[c]atp + h + pan4p --> dpcoa + ppi"]
[null,"ADOCBLS","[c]agdpcbi + rdmbzi --> adocbl + gmp + h"]
[null,"NNDMBRT","[c]dmbzid + nicrnt --> 5prdmbz + h + nac"]
[null,"ADOCBIK","[c]adocbi + atp --> adocbip + adp + h"]
[null,"ACBIPGT","[c]adocbip + gtp + h --> agdpcbi + ppi"]
[null,"HEMEOS","[c]frdp + h2o + pheme --> hemeO + ppi"]
[null,"SHCHD2","[c]nad + shcl --> h + nadh + srch"]
[null,"SHCHF","[c]fe2 + srch --> (3) h + sheme"]
[null,"DXPRIi","[c]dxyl5p + h + nadph --> 2me4p + nadp"]
[null,"DXPS","[c]g3p + h + pyr + h2o --> co2tot + dxyl5p"]
[null,"DHBD","[c]23ddhb + nad <==> 23dhb + h + nadh"]
[null,"ICHORT","[c]h2o + ichor --> 23ddhb + pyr"]
[null,"ENTCS","[c](3) 23dhba + (3) seramp --> (6) amp + enter + (6) h"]
[null,"DHBSr","[c]23dhb + atp <==> 23dhba + ppi"]
[null,"SERASr","[c]atp + h + ser-L <==> ppi + seramp"]
[null,"E4PD","[c]e4p + h2o + nad <==> 4per + (2) h + nadh"]
[null,"DHFR","[c]dhf + h + nadph <==> nadp + thf"]
[null,"DHNPA2","[c]dhnpt --> 6hmhpt + gcald"]
[null,"DHFS","[c]atp + dhpt + glu-L --> adp + dhf + pi"]
[null,"GTPCI","[c]gtp + h2o --> ahdt + for"]
[null,"HPPK2","[c]6hmhpt + atp --> 6hmhptpp + amp + h"]
[null,"DHPS2","[c]4abz + 6hmhptpp --> dhpt + h + ppi"]
[null,"MECDPDH","[c]2mecdp + h --> h2mb4p + h2o"]
[null,"GLUTRS","[c]atp + glu-L + trnaglu --> amp + glutrna + ppi"]
[null,"ALATA_D2","[c]ala-D + pydx5p --> pyam5p + pyr"]
[null,"ALATA_L2","[c]ala-L + pydx5p --> pyam5p + pyr"]
[null,"GTHOr","[c]gthox + h + nadph <==> (2) gthrd + nadp"]
[null,"GLUCYS","[c]atp + cys-L + glu-L --> adp + glucys + h + pi"]
[null,"GTHS","[c]atp + glucys + gly --> adp + gthrd + h + pi"]
[null,"GLUTRR","[c]glutrna + h + nadph --> glu1sa + nadp + trnaglu"]
[null,"PPBNGS","[c](2) 5aop --> h + (2) h2o + ppbng"]
[null,"HMBS","[c]h2o + (4) ppbng --> hmbil + (4) nh4"]
[null,"UPP3S","[c]hmbil --> h2o + uppg3"]
[null,"UPPDC1","[c](4) h + uppg3 + (4) h2o --> (4) co2tot + cpppg3"]
[null,"CPPPGO","[c]cpppg3 + (2) h + o2 --> (2) co2tot + pppg9"]
[null,"PPPGO","[c](1.5) o2 + pppg9 --> (3) h2o + ppp9"]
[null,"FCLT","[c]fe2 + ppp9 --> (2) h + pheme"]
[null,"G1SATi","[c]glu1sa --> 5aop"]
[null,"UPP3MT","[c](2) amet + uppg3 --> (2) ahcys + h + shcl"]
[null,"IPDDIi","[c]ipdp --> dmpp"]
[null,"DMATT","[c]dmpp + ipdp --> grdp + ppi"]
[null,"GRTT","[c]grdp + ipdp --> frdp + ppi"]
[null,"OCTDPS","[c]frdp + (5) ipdp --> octdp + (5) ppi"]
[null,"MEPCT","[c]2me4p + ctp + h --> 4c2me + ppi"]
[null,"CDPMEK","[c]4c2me + atp --> 2p4c2me + adp + h"]
[null,"MECDPS","[c]2p4c2me --> 2mecdp + cmp"]
[null,"NADDP","[c]h2o + nad --> amp + (2) h + nmn"]
[null,"DMPPS","[c]h + h2mb4p + nadh --> dmpp + h2o + nad"]
[null,"IPDPS","[c]h + h2mb4p + nadh --> h2o + ipdp + nad"]
[null,"DHNAOT","[c]dhna + octdp + h2o --> 2dmmq8 + co2tot + h + ppi"]
[null,"NPHS","[c]sbzcoa --> coa + dhna"]
[null,"SUCBZS","[c]2shchc --> h2o + sucbz"]
[null,"OXGDC2","[c]akg + h + thmpp + h2o --> co2tot + ssaltpp"]
[null,"SHCHCS2","[c]ichor + ssaltpp --> 2shchc + pyr + thmpp"]
[null,"SUCBZL","[c]atp + coa + sucbz --> amp + ppi + sbzcoa"]
[null,"ICHORSi","[c]chor --> ichor"]
[null,"AMMQT8_2","[c]2dmmq8 + amet --> ahcys + h + mqn8"]
[null,"QULNS","[c]dhap + iasp --> h + (2) h2o + pi + quln"]
[null,"ASPO3","[c]asp-L + q8 --> iasp + q8h2"]
[null,"ASPO4","[c]asp-L + mqn8 --> iasp + mql8"]
[null,"ASPO5","[c]asp-L + fum --> iasp + succ"]
[null,"ASPO6","[c]asp-L + o2 --> h2o2 + iasp"]
[null,"NNDPR","[c](2) h + prpp + quln + h2o --> co2tot + nicrnt + ppi"]
[null,"NNAT","[c]atp + h + nicrnt --> dnad + ppi"]
[null,"NMNAT","[c]atp + h + nmn --> nad + ppi"]
[null,"NADS1","[c]atp + dnad + nh4 --> amp + h + nad + ppi"]
[null,"DNTPPA","[c]ahdt + h2o --> dhpmp + h + ppi"]
[null,"ADCS","[c]chor + gln-L --> 4adcho + glu-L"]
[null,"ADCL","[c]4adcho --> 4abz + h + pyr"]
[null,"MOHMT","[c]3mob + h2o + mlthf --> 2dhp + thf"]
[null,"PANTS","[c]ala-B + atp + pant-R --> amp + h + pnto-R + ppi"]
[null,"ASP1DC","[c]asp-L + h + h2o --> ala-B + co2tot"]
[null,"DPR","[c]2dhp + h + nadph --> nadp + pant-R"]
[null,"PDX5PS","[c]dxyl5p + nad + phthr --> co2tot + h + h2o + nadh + pdx5p + pi"]
[null,"PERD","[c]4per + nad <==> h + nadh + ohpb"]
[null,"PDX5PO","[c]o2 + pdx5p <==> h2o2 + pydx5p"]
[null,"PYAM5PO","[c]h2o + o2 + pyam5p --> h2o2 + nh4 + pydx5p"]
[null,"PYDXNK","[c]atp + pydxn --> adp + h + pdx5p"]
[null,"PYDAMK","[c]atp + pydam --> adp + h + pyam5p"]
[null,"PYDXK","[c]atp + pydx --> adp + h + pydx5p"]
[null,"RZ5PP","[c]5prdmbz + h2o --> pi + rdmbzi"]
[null,"NNAM","[c]h2o + ncam --> nac + nh4"]
[null,"NAMNPP","[c]atp + h2o + nac + prpp --> adp + nicrnt + pi + ppi"]
[null,"GTPCII2","[c]gtp + (3) h2o --> 25drapp + for + (2) h + ppi"]
[null,"DB4PS","[c]ru5p-D --> db4p + for + h"]
[null,"APRAUR","[c]5apru + h + nadph --> 5aprbu + nadp"]
[null,"DHPPDA2","[c]25drapp + h + h2o --> 5apru + nh4"]
[null,"RBFSa","[c]4r5au + db4p --> dmlz + (2) h2o + pi"]
[null,"RBFK","[c]atp + ribflv --> adp + fmn + h"]
[null,"FMNAT","[c]atp + fmn + h --> fad + ppi"]
[null,"RBFSb","[c](2) dmlz --> 4r5au + ribflv"]
[null,"OHPBAT","[c]glu-L + ohpb <==> akg + phthr"]
[null,"AMPMS","[c]air + h2o --> 4ampm + (2) for + (4) h"]
[null,"PMPK","[c]4ampm + atp --> 2mahmp + adp"]
[null,"HMPK1","[c]4ahmmp + atp --> 4ampm + adp + h"]
[null,"TMPPP","[c]2mahmp + 4mpetz + h --> ppi + thmmp"]
[null,"TMPKr","[c]atp + thmmp <==> adp + thmpp"]
[null,"HETZK","[c]4mhetz + atp --> 4mpetz + adp + h"]
[null,"THZPSN","[c]atp + cys-L + dxyl5p + tyr-L --> 4hba + 4mpetz + ala-L + amp + co2tot + h + ppi"]
[null,"4HTHRS","[c]h2o + phthr --> 4hthr + pi"]
[null,"HBZOPT","[c]4hbz + octdp --> 3ophb + ppi"]
[null,"OPHHX","[c]2oph + (0.5) o2 --> 2ohph"]
[null,"CHRPL","[c]chor --> 4hbz + pyr"]
[null,"OPHBDC","[c]3ophb + h + h2o --> 2oph + co2tot"]
[null,"OMBZLM","[c]2ombzl + amet --> 2ommbl + ahcys + h"]
[null,"OMMBLHX","[c]2ommbl + (0.5) o2 --> 2omhmbl"]
[null,"OHPHM","[c]2ohph + amet --> 2omph + ahcys + h"]
[null,"DMQMT","[c]2omhmbl + amet --> ahcys + h + q8h2"]
[null,"OMPHHX","[c]2omph + (0.5) o2 --> 2ombzl"]
[null,"UDCPDPS","[c]frdp + (8) ipdp --> (8) ppi + udcpdp"]
[null,"DXYLK","[c]atp + dxyl --> adp + dxyl5p + h"]
[null,"NADK","[c]atp + nad --> adp + h + nadp"]
[null,"BPNT","[c]h2o + pap --> amp + pi"]
[null,"ADSK","[c]aps + atp --> adp + h + paps"]
[null,"SADT2","[c]atp + gtp + h2o + so4 --> aps + gdp + pi + ppi"]
[null,"SERAT","[c]accoa + ser-L <==> acser + coa"]
[null,"PAPSR","[c]paps + trdrd --> (2) h + pap + so3 + trdox"]
[null,"SULR","[c](3) h2o + h2s + (3) nadp <==> (5) h + (3) nadph + so3"]
[null,"CYSS","[c]acser + h2s --> ac + cys-L + h"]
[null,"TRPAS1","[c]cys-L + h2o --> h2s + nh4 + pyr"]
[null,"GCALDD","[c]gcald + h2o + nad --> glyclt + (2) h + nadh"]
[null,"MTHFC","[c]h2o + methf <==> 10fthf"]
[null,"MTHFD","[c]mlthf + nadp <==> h + methf + nadph"]
[null,"GLYCL","[c]gly + nad + thf + h2o --> co2tot + mlthf + nadh + nh4"]
[null,"MTHFR2","[c]h + mlthf + nadh --> 5mthf + nad"]
[null,"FTHFD","[c]10fthf + h2o --> for + h + thf"]
[null,"GLUDC","[c]glu-L + h + h2o --> 4abut + co2tot"]
[null,"GLUDy","[c]glu-L + h2o + nadp <==> akg + h + nadph + nh4"]
[null,"GLNS","[c]atp + glu-L + nh4 --> adp + gln-L + h + pi"]
[null,"GLUSy","[c]akg + gln-L + h + nadph --> (2) glu-L + nadp"]
[null,"GLUN","[c]gln-L + h2o --> glu-L + nh4"]
[null,"SERD_D","[c]ser-D --> nh4 + pyr"]
[null,"GHMT2","[c]ser-L + thf --> gly + h2o + mlthf"]
[null,"GLYATi","[c]2aobut + coa --> accoa + gly"]
[null,"PGCD","[c]3pg + nad --> 3php + h + nadh"]
[null,"PSP_L","[c]h2o + pser-L --> pi + ser-L"]
[null,"PSERT","[c]3php + glu-L --> akg + pser-L"]
[null,"SERD_L","[c]ser-L --> nh4 + pyr"]
[null,"THRD","[c]nad + thr-L --> 2aobut + h + nadh"]
[null,"PDH","[c]coa + nad + pyr + h2o --> accoa + co2tot + nadh"]
[null,"G1PP","[c]g1p + h2o --> glc-D + pi"]
[null,"ENO","[c]2pg <==> h2o + pep"]
[null,"FBA","[c]fdp <==> dhap + g3p"]
[null,"FBP","[c]fdp + h2o --> f6p + pi"]
[null,"F6PA","[c]f6p <==> dha + g3p"]
[null,"GAPD","[c]g3p + nad + pi <==> 13dpg + h + nadh"]
[null,"GLCS1","[c]adpglc --> adp + glycogen + h"]
[null,"GLGC","[c]atp + g1p + h --> adpglc + ppi"]
[null,"GLCP","[c]glycogen + pi --> g1p"]
[null,"HEX1","[c]atp + glc-D --> adp + g6p + h"]
[null,"PGM","[c]2pg <==> 3pg"]
[null,"PFK","[c]atp + f6p --> adp + fdp + h"]
[null,"PGI","[c]g6p <==> f6p"]
[null,"PGK","[c]3pg + atp <==> 13dpg + adp"]
[null,"PPS","[c]atp + h2o + pyr --> amp + (2) h + pep + pi"]
[null,"PYK","[c]adp + h + pep --> atp + pyr"]
[null,"TPI","[c]dhap <==> g3p"]
[null,"TRSAR","[c]2h3oppan + h + nadh --> glyc-R + nad"]
[null,"GLXCL","[c](2) glx + h + h2o --> 2h3oppan + co2tot"]
[null,"GLYCK","[c]atp + glyc-R --> 3pg + adp + h"]
[null,"GLYCLTDy","[c]glx + h + nadph --> glyclt + nadp"]
[null,"GLYCLTDx","[c]glx + h + nadh --> glyclt + nad"]
[null,"PRMICIi","[c]prfp --> prlp"]
[null,"IGPDH","[c]eig3p --> h2o + imacp"]
[null,"HISTP","[c]h2o + hisp --> histd + pi"]
[null,"HSTPT","[c]glu-L + imacp --> akg + hisp"]
[null,"HISTD","[c]h2o + histd + (2) nad --> (3) h + his-L + (2) nadh"]
[null,"IG3PS","[c]gln-L + prlp --> aicar + eig3p + glu-L + h"]
[null,"ATPPRT","[c]atp + prpp --> ppi + prbatp"]
[null,"PRATPP","[c]h2o + prbatp --> h + ppi + prbamp"]
[null,"PRAMPC","[c]h2o + prbamp --> prfp"]
[null,"PRPPS","[c]atp + r5p <==> amp + h + prpp"]
[null,"ACCOACr","[c]accoa + atp + hco3 <==> adp + h + malcoa + pi"]
[null,"ACACT1r","[c](2) accoa <==> aacoa + coa"]
[null,"CDAPPA_EC","[c](0.02) cdpdag1 + h2o --> cmp + (2) h + (0.02) pa_EC"]
[null,"DASYN_EC","[c]ctp + h + (0.02) pa_EC <==> (0.02) cdpdag1 + ppi"]
[null,"CLPNS_EC","[c](0.04) pg_EC <==> (0.02) clpn_EC + glyc"]
[null,"C140SN","[c]actACP + (17) h + (5) malACP + (12) nadph --> (5) ACP + (5) co2tot + h2o + myrsACP + (12) nadp"]
[null,"C120SN","[c]actACP + (14) h + (4) malACP + (10) nadph --> (4) ACP + (4) co2tot + ddcaACP + h2o + (10) nadp"]
[null,"MACPD","[c]h + malACP + h2o --> acACP + co2tot"]
[null,"KAS14","[c]acACP + h + malACP + h2o --> ACP + actACP + co2tot"]
[null,"MCOATA","[c]ACP + malcoa <==> coa + malACP"]
[null,"C160SN","[c]actACP + (20) h + (6) malACP + (14) nadph --> (6) ACP + (6) co2tot + h2o + (14) nadp + palmACP"]
[null,"KAS16","[c]ddcaACP + (2) h + malACP + nadph + h2o --> 3hmrsACP + ACP + co2tot + nadp"]
[null,"C181SN","[c]actACP + (22) h + (7) malACP + (15) nadph --> (7) ACP + (7) co2tot + h2o + (15) nadp + octeACP"]
[null,"C141SN","[c]actACP + (16) h + (5) malACP + (11) nadph --> (5) ACP + (5) co2tot + h2o + (11) nadp + tdeACP"]
[null,"KAS15","[c]accoa + h + malACP + h2o --> actACP + co2tot + coa"]
[null,"ACOATA","[c]ACP + accoa <==> acACP + coa"]
[null,"C161SN","[c]actACP + (19) h + (6) malACP + (13) nadph --> (6) ACP + (6) co2tot + h2o + hdeACP + (13) nadp"]
[null,"FAO2","[c]atp + (8) coa + (7) fad + (7) h2o + hdca + (7) nad --> (8) accoa + amp + (7) fadh2 + (7) h + (7) nadh + ppi"]
[null,"FAO1","[c]atp + (7) coa + (6) fad + (6) h2o + (6) nad + ttdca --> (7) accoa + amp + (6) fadh2 + (6) h + (6) nadh + ppi"]
[null,"FAO3","[c]atp + (9) coa + (8) fad + (8) h2o + (8) nad + ocdca --> (9) accoa + amp + (8) fadh2 + (8) h + (8) nadh + ppi"]
[null,"PGPP_EC","[c]h2o + (0.02) pgp_EC --> (0.02) pg_EC + pi"]
[null,"PGSA_EC","[c](0.02) cdpdag1 + glyc3p <==> cmp + h + (0.02) pgp_EC"]
[null,"PASYN_EC","[c]glyc3p + (0.14) hdeACP + (0.04) myrsACP + octeACP + (0.72) palmACP + (0.1) tdeACP --> (2) ACP + (0.02) pa_EC"]
[null,"PSD_EC","[c]h + (0.02) ps_EC + h2o --> co2tot + (0.02) pe_EC"]
[null,"PSSA_EC","[c](0.02) cdpdag1 + ser-L <==> cmp + h + (0.02) ps_EC"]
[null,"AHC","[c]ahcys + h2o <==> adn + hcys-L"]
[null,"DHPTDC","[c]dhptd --> h2o + hmfurn"]
[null,"RHCCE","[c]rhcys --> dhptd + hcys-L"]
[null,"HSST","[c]hom-L + succoa --> coa + suchms"]
[null,"SHSL1","[c]cys-L + suchms --> cyst-L + h + succ"]
[null,"CYSTL","[c]cyst-L + h2o --> hcys-L + nh4 + pyr"]
[null,"METS","[c]5mthf + hcys-L --> met-L + thf"]
[null,"METAT","[c]atp + h2o + met-L --> amet + pi + ppi"]
[null,"AHCYSNS","[c]ahcys + h2o --> ade + rhcys"]
[null,"LGTHL","[c]gthrd + mthgxl --> lgt-S"]
[null,"GLYOX","[c]h2o + lgt-S --> gthrd + h + lac-D"]
[null,"MGSA","[c]dhap --> mthgxl + pi"]
[null,"UGLYCH","[c](2) h + (2) h2o + urdglyc --> co2tot + glx + (2) nh4"]
[null,"ALLTN","[c]alltn + h2o --> alltt + h"]
[null,"ALLTAH","[c]alltt + h2o --> urdglyc + urea"]
[null,"CYNTAH","[c]cynt + (3) h + hco3  + (2) h2o --> (2) co2tot + nh4"]
[null,"CMPN","[c]cmp + h2o --> csn + r5p"]
[null,"ADA","[c]adn + h + h2o --> ins + nh4"]
[null,"DADA","[c]dad-2 + h + h2o --> din + nh4"]
[null,"ADNK1","[c]adn + atp --> adp + amp + h"]
[null,"ADK1","[c]amp + atp <==> (2) adp"]
[null,"DADK","[c]atp + damp <==> adp + dadp"]
[null,"ADK4","[c]amp + itp <==> adp + idp"]
[null,"ADK3","[c]amp + gtp <==> adp + gdp"]
[null,"AMPN","[c]amp + h2o --> ade + r5p"]
[null,"AP4AH","[c]ap4a + h2o --> (2) adp + (2) h"]
[null,"GP4GH","[c]gp4g + h2o --> (2) gdp + (2) h"]
[null,"AP5AH","[c]ap5a + h2o --> adp + atp + (2) h"]
[null,"ADPT","[c]ade + prpp --> amp + ppi"]
[null,"CYTD","[c]cytd + h + h2o --> nh4 + uri"]
[null,"DCYTD","[c]dcyt + h + h2o --> duri + nh4"]
[null,"CYTK2","[c]atp + dcmp <==> adp + dcdp"]
[null,"CYTK1","[c]atp + cmp <==> adp + cdp"]
[null,"UMPK","[c]atp + ump <==> adp + udp"]
[null,"CSND","[c]csn + h + h2o --> nh4 + ura"]
[null,"ADNCYC","[c]atp --> camp + ppi"]
[null,"DCTPD","[c]dctp + h + h2o --> dutp + nh4"]
[null,"TMDPP","[c]pi + thymd <==> 2dr1p + thym"]
[null,"DURIPP","[c]duri + pi <==> 2dr1p + ura"]
[null,"NTPTP1","[c]dgtp + h2o --> dgsn + pppi"]
[null,"NTPTP2","[c]gtp + h2o --> gsn + pppi"]
[null,"DUTPDP","[c]dutp + h2o --> dump + h + ppi"]
[null,"GK1","[c]atp + gmp <==> adp + gdp"]
[null,"DGK1","[c]atp + dgmp <==> adp + dgdp"]
[null,"XPPT","[c]prpp + xan --> ppi + xmp"]
[null,"HXPRT","[c]hxan + prpp --> imp + ppi"]
[null,"GUAPRT","[c]gua + prpp --> gmp + ppi"]
[null,"INSK","[c]atp + ins --> adp + h + imp"]
[null,"GSNK","[c]atp + gsn --> adp + gmp + h"]
[null,"NTPP3","[c]dctp + h2o --> dcmp + h + ppi"]
[null,"NTPP4","[c]ctp + h2o --> cmp + h + ppi"]
[null,"NTPP5","[c]datp + h2o --> damp + h + ppi"]
[null,"NTPP6","[c]atp + h2o --> amp + h + ppi"]
[null,"NTPP7","[c]dttp + h2o --> dtmp + h + ppi"]
[null,"NTPP8","[c]h2o + utp --> h + ppi + ump"]
[null,"NTPP1","[c]dgtp + h2o --> dgmp + h + ppi"]
[null,"NTPP2","[c]gtp + h2o --> gmp + h + ppi"]
[null,"NDPK1","[c]atp + gdp <==> adp + gtp"]
[null,"NDPK2","[c]atp + udp <==> adp + utp"]
[null,"NDPK3","[c]atp + cdp <==> adp + ctp"]
[null,"NDPK5","[c]atp + dgdp <==> adp + dgtp"]
[null,"NDPK6","[c]atp + dudp <==> adp + dutp"]
[null,"NDPK7","[c]atp + dcdp <==> adp + dctp"]
[null,"NDPK8","[c]atp + dadp <==> adp + datp"]
[null,"NDPK4","[c]atp + dtdp <==> adp + dttp"]
[null,"RNDR1","[c]adp + trdrd --> dadp + h2o + trdox"]
[null,"RNDR2","[c]gdp + trdrd --> dgdp + h2o + trdox"]
[null,"RNDR4","[c]trdrd + udp --> dudp + h2o + trdox"]
[null,"RNDR3","[c]cdp + trdrd --> dcdp + h2o + trdox"]
[null,"RNTR1","[c]atp + trdrd --> datp + h2o + trdox"]
[null,"RNTR2","[c]gtp + trdrd --> dgtp + h2o + trdox"]
[null,"RNTR3","[c]ctp + trdrd --> dctp + h2o + trdox"]
[null,"RNTR4","[c]trdrd + utp --> dutp + h2o + trdox"]
[null,"URIDK2r","[c]atp + dump <==> adp + dudp"]
[null,"DURIK1","[c]atp + duri --> adp + dump + h"]
[null,"TMDK1","[c]atp + thymd --> adp + dtmp + h"]
[null,"TMDS","[c]dump + mlthf --> dhf + dtmp"]
[null,"DTMPK","[c]atp + dtmp <==> adp + dtdp"]
[null,"URIK2","[c]gtp + uri --> gdp + h + ump"]
[null,"CYTDK2","[c]cytd + gtp --> cmp + gdp + h"]
[null,"PYNP2r","[c]pi + uri <==> r1p + ura"]
[null,"UPPRT","[c]prpp + ura --> ppi + ump"]
[null,"NTD1","[c]dump + h2o --> duri + pi"]
[null,"NTD5","[c]dtmp + h2o --> pi + thymd"]
[null,"NTD6","[c]damp + h2o --> dad-2 + pi"]
[null,"NTD8","[c]dgmp + h2o --> dgsn + pi"]
[null,"NTD3","[c]dcmp + h2o --> dcyt + pi"]
[null,"NTD4","[c]cmp + h2o --> cytd + pi"]
[null,"NTD7","[c]amp + h2o --> adn + pi"]
[null,"NTD9","[c]gmp + h2o --> gsn + pi"]
[null,"NTD11","[c]h2o + imp --> ins + pi"]
[null,"NTD10","[c]h2o + xmp --> pi + xtsn"]
[null,"NTD2","[c]h2o + ump --> pi + uri"]
[null,"PUNP6","[c]din + pi <==> 2dr1p + hxan"]
[null,"PUNP5","[c]ins + pi <==> hxan + r1p"]
[null,"PUNP2","[c]dad-2 + pi <==> 2dr1p + ade"]
[null,"PUNP4","[c]dgsn + pi <==> 2dr1p + gua"]
[null,"PUNP1","[c]adn + pi <==> ade + r1p"]
[null,"PUNP3","[c]gsn + pi <==> gua + r1p"]
[null,"PUNP7","[c]pi + xtsn <==> r1p + xan"]
[null,"GUAD","[c]gua + h + h2o --> nh4 + xan"]
[null,"ADD","[c]ade + h + h2o --> hxan + nh4"]
[null,"L-LACD2","[c]lac-L + q8 --> pyr + q8h2"]
[null,"L-LACD3","[c]lac-L + mqn8 --> mql8 + pyr"]
[null,"CRNBTCT","[c]bbtcoa + crn <==> crncoa + gbbtn"]
[null,"CRNCBCT","[c]crn + ctbtcoa <==> crncoa + ctbt"]
[null,"CRNCDH","[c]crncoa <==> ctbtcoa + h2o"]
[null,"CYTBD","(2) h[c] + (0.5) o2[c] + q8h2[c] --> (2) h[e] + h2o[c] + q8[c]"]
[null,"CYTBO3","(2.5) h[c] + (0.5) o2[c] + q8h2[c] --> (2.5) h[e] + h2o[c] + q8[c]"]
[null,"LDH_D2","[c]lac-D + q8 --> pyr + q8h2"]
[null,"DMSOR1","[c]dmso + mql8 --> dms + h2o + mqn8"]
[null,"DMSOR2","[c]2dmmql8 + dmso --> 2dmmq8 + dms + h2o"]
[null,"TMAOR1","[c]h + mql8 + tmao --> h2o + mqn8 + tma"]
[null,"TMAOR2","[c]2dmmql8 + h + tmao --> 2dmmq8 + h2o + tma"]
[null,"FDH2","for[c] + (3) h[c] + q8[c] + h2o[c]--> co2tot[c] + (2) h[e] + q8h2[c]"]
[null,"FDH3","for[c] + (3) h[c] + mqn8[c] + h2o[c] --> co2tot[c] + (2) h[e] + mql8[c]"]
[null,"GLCDe","glc-D[e] + h2o[e] + q8[c] --> glcn[e] + h[e] + q8h2[c]"]
[null,"G3PD7","[c]2dmmq8 + glyc3p --> 2dmmql8 + dhap"]
[null,"G3PD6","[c]glyc3p + mqn8 --> dhap + mql8"]
[null,"G3PD5","[c]glyc3p + q8 --> dhap + q8h2"]
[null,"HYD3","2dmmq8[c] + (2) h[c] + h2[c] --> 2dmmql8[c] + (2) h[e]"]
[null,"HYD1","(2) h[c] + h2[c] + q8[c] --> (2) h[e] + q8h2[c]"]
[null,"HYD2","(2) h[c] + h2[c] + mqn8[c] --> (2) h[e] + mql8[c]"]
[null,"NO3R1","(2) h[c] + no3[c] + q8h2[c] --> (2) h[e] + h2o[c] + no2[c] + q8[c]"]
[null,"NO3R2","(2) h[c] + mql8[c] + no3[c] --> (2) h[e] + h2o[c] + mqn8[c] + no2[c]"]
[null,"NADH5","[c]h + nadh + q8 --> nad + q8h2"]
[null,"NADH9","[c]2dmmq8 + h + nadh --> 2dmmql8 + nad"]
[null,"NADH10","[c]h + mqn8 + nadh --> mql8 + nad"]
[null,"NTRIR2x","[c](5) h + (3) nadh + no2 --> (2) h2o + (3) nad + nh4"]
[null,"NADH6","(4.5) h[c] + nadh[c] + q8[c] --> (3.5) h[e] + nad[c] + q8h2[c]"]
[null,"NADH7","(3) h[c] + mqn8[c] + nadh[c] --> (2) h[e] + mql8[c] + nad[c]"]
[null,"NADH8","2dmmq8[c] + (3.8) h[c] + nadh[c] --> 2dmmql8[c] + (2.8) h[e] + nad[c]"]
[null,"THD2","(2) h[e] + nadh[c] + nadp[c] --> (2) h[c] + nad[c] + nadph[c]"]
[null,"POX","[c](2) h2o + pyr + q8 --> ac + co2tot + q8h2"]
[null,"SUCD4","[c]fadh2 + q8 <==> fad + q8h2"]
[null,"TEST_NADTRHD","[c]nad + nadph --> nadh + nadp"]
[null,"TMAOR1e","h[e] + mql8[c] + tmao[e] --> h2o[e] + mqn8[c] + tma[e]"]
[null,"TMAOR2e","2dmmql8[c] + h[e] + tmao[e] --> 2dmmq8[c] + h2o[e] + tma[e]"]
[null,"DMSOR1e","dmso[e] + mql8[c] --> dms[e] + h2o[e] + mqn8[c]"]
[null,"DMSOR2e","2dmmql8[c] + dmso[e] --> 2dmmq8[c] + dms[e] + h2o[e]"]
[null,"TRDR","[c]h + nadph + trdox --> nadp + trdrd"]
[null,"PGL","[c]6pgl + h2o --> 6pgc + h"]
[null,"EDA","[c]2ddg6p --> g3p + pyr"]
[null,"EDD","[c]6pgc --> 2ddg6p + h2o"]
[null,"GND","[c]6pgc + nadp + h2o --> co2tot + nadph + ru5p-D"]
[null,"RPE","[c]ru5p-D <==> xu5p-D"]
[null,"RPI","[c]r5p <==> ru5p-D"]
[null,"TALA","[c]g3p + s7p <==> e4p + f6p"]
[null,"TKT1","[c]r5p + xu5p-D <==> g3p + s7p"]
[null,"TKT2","[c]e4p + xu5p-D <==> f6p + g3p"]
[null,"G6PDH2r","[c]g6p + nadp <==> 6pgl + h + nadph"]
[null,"GMPS2","[c]atp + gln-L + h2o + xmp --> amp + glu-L + gmp + (2) h + ppi"]
[null,"IMPD","[c]h2o + imp + nad --> h + nadh + xmp"]
[null,"GMPR","[c]gmp + (2) h + nadph --> imp + nadp + nh4"]
[null,"ADSS","[c]asp-L + gtp + imp --> dcamp + gdp + (2) h + pi"]
[null,"ADSL2r","[c]25aics <==> aicar + fum"]
[null,"ADSL1r","[c]dcamp <==> amp + fum"]
[null,"PRASCS","[c]5aizc + asp-L + atp <==> 25aics + adp + h + pi"]
[null,"PRAGSr","[c]atp + gly + pram <==> adp + gar + h + pi"]
[null,"AIRC3","[c]5aizc <==> 5caiz"]
[null,"GLUPRT","[c]gln-L + h2o + prpp --> glu-L + ppi + pram"]
[null,"AICART","[c]10fthf + aicar <==> fprica + thf"]
[null,"IMPC","[c]h2o + imp <==> fprica"]
[null,"AIRC2","[c]air + atp + hco3 --> 5caiz + adp + h + pi"]
[null,"PRFGS","[c]atp + fgam + gln-L + h2o --> adp + fpram + glu-L + h + pi"]
[null,"PRAIS","[c]atp + fpram --> adp + air + (2) h + pi"]
[null,"GARFT","[c]10fthf + gar <==> fgam + h + thf"]
[null,"GART","[c]atp + for + gar --> adp + fgam + h + pi"]
[null,"ASPCT","[c]asp-L + cbp --> cbasp + h + pi"]
[null,"DHORTS","[c]dhor-S + h2o <==> cbasp + h"]
[null,"DHORD2","[c]dhor-S + q8 --> orot + q8h2"]
[null,"DHORD5","[c]dhor-S + mqn8 --> mql8 + orot"]
[null,"ORPT","[c]orot5p + ppi <==> orot + prpp"]
[null,"OMPDC","[c]h + orot5p + h2o --> co2tot + ump"]
[null,"CTPS2","[c]atp + gln-L + h2o + utp --> adp + ctp + glu-L + (2) h + pi"]
[null,"CBMK","[c]atp + co2tot + nh4 --> adp + cbp + (2) h + h2o"]
[null,"AMANAPE","[c]acmanap --> acgam6p"]
[null,"AMANK","[c]acmana + atp --> acmanap + adp + h"]
[null,"ALLTNt2r","alltn[e] + h[e] <==> alltn[c] + h[c]"]
[null,"ARGORNt7","arg-L[e] + orn[c] <==> arg-L[c] + orn[e]"]
[null,"ACACt2","acac[e] + h[e] <==> acac[c] + h[c]"]
[null,"BUTt2r","but[e] + h[e] <==> but[c] + h[c]"]
[null,"CYNTt2","cynt[e] + h[e] --> cynt[c] + h[c]"]
[null,"GALCTt2r","galct-D[e] + h[e] <==> galct-D[c] + h[c]"]
[null,"GLCRt2r","glcr[e] + h[e] <==> glcr[c] + h[c]"]
[null,"PPPNt2r","h[e] + pppn[e] <==> h[c] + pppn[c]"]
[null,"HPPPNt2r","3hpppn[e] + h[e] <==> 3hpppn[c] + h[c]"]
[null,"HCINNMt2r","3hcinnm[e] + h[e] <==> 3hcinnm[c] + h[c]"]
[null,"GLUABUTt7","4abut[c] + glu-L[e] <==> 4abut[e] + glu-L[c]"]
[null,"ALAt2r","ala-L[e] + h[e] <==> ala-L[c] + h[c]"]
[null,"URAt2r","h[e] + ura[e] <==> h[c] + ura[c]"]
[null,"GLYBt2r","glyb[e] + h[e] <==> glyb[c] + h[c]"]
[null,"CHLabc","atp[c] + chol[e] + h2o[c] --> adp[c] + chol[c] + h[c] + pi[c]"]
[null,"GLYBabc","atp[c] + glyb[e] + h2o[c] --> adp[c] + glyb[c] + h[c] + pi[c]"]
[null,"TARTRt7","succ[c] + tartr-L[e] <==> succ[e] + tartr-L[c]"]
[null,"SUCCabc","atp[c] + h2o[c] + succ[e] --> adp[c] + h[c] + pi[c] + succ[c]"]
[null,"GUAt2","gua[e] + h[e] --> gua[c] + h[c]"]
[null,"XANt2","h[e] + xan[e] --> h[c] + xan[c]"]
[null,"ACKr","[c]ac + atp <==> actp + adp"]
[null,"ACS","[c]ac + atp + coa --> accoa + amp + ppi"]
[null,"ADHEr","[c]accoa + (2) h + (2) nadh <==> coa + etoh + (2) nad"]
[null,"LDH_D","[c]lac-D + nad <==> h + nadh + pyr"]
[null,"FHL","[c]for + h + h2o --> co2tot + h2"]
[null,"PTAr","[c]accoa + pi <==> actp + coa"]
[null,"PFL","[c]coa + pyr --> accoa + for"]
[null,"SDPTA","[c]akg + sl26da <==> glu-L + sl2a6o"]
[null,"ASAD","[c]aspsa + nadp + pi <==> 4pasp + h + nadph"]
[null,"DHDPS","[c]aspsa + pyr --> 23dhdp + h + (2) h2o"]
[null,"DHDPRy","[c]23dhdp + h + nadph --> nadp + thdp"]
[null,"THDPS","[c]h2o + succoa + thdp --> coa + sl2a6o"]
[null,"SDPDS","[c]h2o + sl26da --> 26dap-LL + succ"]
[null,"DAPE","[c]26dap-LL <==> 26dap-M"]
[null,"LYSDC","[c]h + lys-L + h2o --> 15dap + co2tot"]
[null,"THRAr","[c]thr-L <==> acald + gly"]
[null,"DAPDC","[c]26dap-M + h + h2o --> co2tot + lys-L"]
[null,"HSDy","[c]hom-L + nadp <==> aspsa + h + nadph"]
[null,"ASPK","[c]asp-L + atp <==> 4pasp + adp"]
[null,"HSK","[c]atp + hom-L --> adp + h + phom"]
[null,"THRS","[c]h2o + phom --> pi + thr-L"]
[null,"12PPDt","12ppd-S[e] <==> 12ppd-S[c]"]
[null,"NMNt7","h2o[c] + nmn[e] --> h[c] + ncam[c] + r5p[c]"]
[null,"ACALDt","acald[e] <==> acald[c]"]
[null,"GUAt","gua[e] <==> gua[c]"]
[null,"HYXNt","hxan[e] <==> hxan[c]"]
[null,"XANt","xan[e] <==> xan[c]"]
[null,"NACUP","nac[e] --> nac[c]"]
[null,"ASNabc","asn-L[e] + atp[c] + h2o[c] --> adp[c] + asn-L[c] + h[c] + pi[c]"]
[null,"ASNt2r","asn-L[e] + h[e] <==> asn-L[c] + h[c]"]
[null,"DAPabc","26dap-M[e] + atp[c] + h2o[c] --> 26dap-M[c] + adp[c] + h[c] + pi[c]"]
[null,"CYSabc","atp[c] + cys-L[e] + h2o[c] --> adp[c] + cys-L[c] + h[c] + pi[c]"]
[null,"ACt2r","ac[e] + h[e] <==> ac[c] + h[c]"]
[null,"ETOHt2r","etoh[e] + h[e] <==> etoh[c] + h[c]"]
[null,"PYRt2r","h[e] + pyr[e] <==> h[c] + pyr[c]"]
[null,"O2t","o2[e] <==> o2[c]"]
[null,"CO2t","co2tot[e] + h2o[c] <==> co2tot[c] + h2o[e]"]
[null,"H2Ot","h2o[e] <==> h2o[c]"]
[null,"DHAt","dha[e] <==> dha[c]"]
[null,"NH3t","nh4[e] <==> nh4[c]"]
[null,"ARBt2r","arab-L[e] + h[e] <==> arab-L[c] + h[c]"]
[null,"ARBabc","arab-L[e] + atp[c] + h2o[c] --> adp[c] + arab-L[c] + h[c] + pi[c]"]
[null,"HISt2r","h[e] + his-L[e] <==> h[c] + his-L[c]"]
[null,"PHEt2r","h[e] + phe-L[e] <==> h[c] + phe-L[c]"]
[null,"LEUt2r","h[e] + leu-L[e] <==> h[c] + leu-L[c]"]
[null,"VALt2r","h[e] + val-L[e] <==> h[c] + val-L[c]"]
[null,"ILEt2r","h[e] + ile-L[e] <==> h[c] + ile-L[c]"]
[null,"CBL1abc","atp[c] + cbl1[e] + h2o[c] --> adp[c] + cbl1[c] + h[c] + pi[c]"]
[null,"CADVt","15dap[c] + h[e] + lys-L[e] --> 15dap[e] + h[c] + lys-L[c]"]
[null,"CRNt7","crn[e] + gbbtn[c] --> crn[c] + gbbtn[e]"]
[null,"NAt3_1","h[e] + na1[c] <==> h[c] + na1[e]"]
[null,"CITt7","cit[e] + succ[c] --> cit[c] + succ[e]"]
[null,"CSNt2","csn[e] + h[e] --> csn[c] + h[c]"]
[null,"MALTpts","malt[e] + pep[c] --> malt6p[c] + pyr[c]"]
[null,"ACGApts","acgam[e] + pep[c] --> acgam6p[c] + pyr[c]"]
[null,"DALAt2r","ala-D[e] + h[e] <==> ala-D[c] + h[c]"]
[null,"DSERt2r","h[e] + ser-D[e] <==> h[c] + ser-D[c]"]
[null,"GLYt2r","gly[e] + h[e] <==> gly[c] + h[c]"]
[null,"SULabc","atp[c] + h2o[c] + so4[e] --> adp[c] + h[c] + pi[c] + so4[c]"]
[null,"ASPt2_2","asp-L[e] + (2) h[e] --> asp-L[c] + (2) h[c]"]
[null,"FUMt2_2","fum[e] + (2) h[e] --> fum[c] + (2) h[c]"]
[null,"MALt2_2","(2) h[e] + mal-L[e] --> (2) h[c] + mal-L[c]"]
[null,"SUCCt2_2","(2) h[e] + succ[e] --> (2) h[c] + succ[c]"]
[null,"ASPt2_3","asp-L[e] + (3) h[e] --> asp-L[c] + (3) h[c]"]
[null,"MALt2_3","(3) h[e] + mal-L[e] --> (3) h[c] + mal-L[c]"]
[null,"SUCCt2_3","(3) h[e] + succ[e] --> (3) h[c] + succ[c]"]
[null,"SUCCt2b","h[c] + succ[c] --> h[e] + succ[e]"]
[null,"FUMt2_3","fum[e] + (3) h[e] --> fum[c] + (3) h[c]"]
[null,"SUCFUMt","fum[e] + succ[c] <==> fum[c] + succ[e]"]
[null,"GALCTNt2r","galctn-D[e] + h[e] <==> galctn-D[c] + h[c]"]
[null,"GALURt2r","galur[e] + h[e] <==> galur[c] + h[c]"]
[null,"GLCURt2r","glcur[e] + h[e] <==> glcur[c] + h[c]"]
[null,"OCDCAt2","h[e] + ocdca[e] --> h[c] + ocdca[c]"]
[null,"HDCAt2","h[e] + hdca[e] --> h[c] + hdca[c]"]
[null,"TTDCAt2","h[e] + ttdca[e] --> h[c] + ttdca[c]"]
[null,"FE2abc","atp[c] + fe2[e] + h2o[c] --> adp[c] + fe2[c] + h[c] + pi[c]"]
[null,"FORt","for[e] <==> for[c]"]
[null,"FUCt","fuc-L[e] + h[e] <==> fuc-L[c] + h[c]"]
[null,"ABUTt2","4abut[e] + h[e] --> 4abut[c] + h[c]"]
[null,"GALt2","gal[e] + h[e] --> gal[c] + h[c]"]
[null,"GLCt2","glc-D[e] + h[e] --> glc-D[c] + h[c]"]
[null,"GALTpts","galt[e] + pep[c] --> galt1p[c] + pyr[c]"]
[null,"GLNabc","atp[c] + gln-L[e] + h2o[c] --> adp[c] + gln-L[c] + h[c] + pi[c]"]
[null,"GLYCt","glyc[c] <==> glyc[e]"]
[null,"GLYALDt","glyald[e] <==> glyald[c]"]
[null,"UREAt","urea[e] <==> urea[c]"]
[null,"GLYC3Pt6","glyc3p[e] + pi[c] --> glyc3p[c] + pi[e]"]
[null,"ASPabc","asp-L[e] + atp[c] + h2o[c] --> adp[c] + asp-L[c] + h[c] + pi[c]"]
[null,"GLUabc","atp[c] + glu-L[e] + h2o[c] --> adp[c] + glu-L[c] + h[c] + pi[c]"]
[null,"ASPt2","asp-L[e] + h[e] --> asp-L[c] + h[c]"]
[null,"GLUt2r","glu-L[e] + h[e] <==> glu-L[c] + h[c]"]
[null,"GLUt4","glu-L[e] + na1[e] --> glu-L[c] + na1[c]"]
[null,"ORNabc","atp[c] + h2o[c] + orn[e] --> adp[c] + h[c] + orn[c] + pi[c]"]
[null,"ARGabc","arg-L[e] + atp[c] + h2o[c] --> adp[c] + arg-L[c] + h[c] + pi[c]"]
[null,"HISabc","atp[c] + h2o[c] + his-L[e] --> adp[c] + h[c] + his-L[c] + pi[c]"]
[null,"LYSabc","atp[c] + h2o[c] + lys-L[e] --> adp[c] + h[c] + lys-L[c] + pi[c]"]
[null,"IDONt2r","h[e] + idon-L[e] <==> h[c] + idon-L[c]"]
[null,"GLCNt2r","glcn[e] + h[e] <==> glcn[c] + h[c]"]
[null,"DDGLCNt2r","2ddglcn[e] + h[e] <==> 2ddglcn[c] + h[c]"]
[null,"Kabc","atp[c] + h2o[c] + k[e] --> adp[c] + h[c] + k[c] + pi[c]"]
[null,"AKGt2r","akg[e] + h[e] <==> akg[c] + h[c]"]
[null,"LCTSt","h[e] + lcts[e] <==> h[c] + lcts[c]"]
[null,"ILEabc","atp[c] + h2o[c] + ile-L[e] --> adp[c] + h[c] + ile-L[c] + pi[c]"]
[null,"THRabc","atp[c] + h2o[c] + thr-L[e] --> adp[c] + h[c] + pi[c] + thr-L[c]"]
[null,"ALAabc","ala-L[e] + atp[c] + h2o[c] --> adp[c] + ala-L[c] + h[c] + pi[c]"]
[null,"VALabc","atp[c] + h2o[c] + val-L[e] --> adp[c] + h[c] + pi[c] + val-L[c]"]
[null,"LEUabc","atp[c] + h2o[c] + leu-L[e] --> adp[c] + h[c] + leu-L[c] + pi[c]"]
[null,"D-LACt2","h[e] + lac-D[e] <==> h[c] + lac-D[c]"]
[null,"GLYCLTt2r","glyclt[e] + h[e] <==> glyclt[c] + h[c]"]
[null,"L-LACt2r","h[e] + lac-L[e] <==> h[c] + lac-L[c]"]
[null,"LYSt2r","h[e] + lys-L[e] <==> h[c] + lys-L[c]"]
[null,"MALTPTabc","atp[c] + h2o[c] + maltpt[e] --> adp[c] + h[c] + maltpt[c] + pi[c]"]
[null,"MALTabc","atp[c] + h2o[c] + malt[e] --> adp[c] + h[c] + malt[c] + pi[c]"]
[null,"MALTTTRabc","atp[c] + h2o[c] + maltttr[e] --> adp[c] + h[c] + maltttr[c] + pi[c]"]
[null,"MALTHXabc","atp[c] + h2o[c] + malthx[e] --> adp[c] + h[c] + malthx[c] + pi[c]"]
[null,"MALTTRabc","atp[c] + h2o[c] + malttr[e] --> adp[c] + h[c] + malttr[c] + pi[c]"]
[null,"FRUpts2","fru[e] + pep[c] --> f6p[c] + pyr[c]"]
[null,"MANpts","man[e] + pep[c] --> man6p[c] + pyr[c]"]
[null,"GAMpts","gam[e] + pep[c] --> gam6p[c] + pyr[c]"]
[null,"MELIBt2","h[e] + melib[e] --> h[c] + melib[c]"]
[null,"METabc","atp[c] + h2o[c] + met-L[e] --> adp[c] + h[c] + met-L[c] + pi[c]"]
[null,"METDabc","atp[c] + h2o[c] + met-D[e] --> adp[c] + h[c] + met-D[c] + pi[c]"]
[null,"GALabc","atp[c] + gal[e] + h2o[c] --> adp[c] + gal[c] + h[c] + pi[c]"]
[null,"INDOLEt2r","h[e] + indole[e] <==> h[c] + indole[c]"]
[null,"ACNAMt2","acnam[e] + h[e] --> acnam[c] + h[c]"]
[null,"NO3t7","no2[c] + no3[e] --> no2[e] + no3[c]"]
[null,"NO2t2r","h[e] + no2[e] <==> h[c] + no2[c]"]
[null,"NAt3_2","(2) h[e] + na1[c] --> (2) h[c] + na1[e]"]
[null,"NAt3_1.5","(3) h[e] + (2) na1[c] --> (3) h[c] + (2) na1[e]"]
[null,"GSNt2","gsn[e] + h[e] --> gsn[c] + h[c]"]
[null,"DGSNt2","dgsn[e] + h[e] --> dgsn[c] + h[c]"]
[null,"DINSt2","din[e] + h[e] --> din[c] + h[c]"]
[null,"DCYTt2","dcyt[e] + h[e] --> dcyt[c] + h[c]"]
[null,"DURIt2","duri[e] + h[e] --> duri[c] + h[c]"]
[null,"DADNt2","dad-2[e] + h[e] --> dad-2[c] + h[c]"]
[null,"PNTOt4","na1[e] + pnto-R[e] --> na1[c] + pnto-R[c]"]
[null,"PIt2r","h[e] + pi[e] <==> h[c] + pi[c]"]
[null,"NMNP","nmn[e] --> nmn[c]"]
[null,"PTRCabc","atp[c] + h2o[c] + ptrc[e] --> adp[c] + h[c] + pi[c] + ptrc[c]"]
[null,"SPMDabc","atp[c] + h2o[c] + spmd[e] --> adp[c] + h[c] + pi[c] + spmd[c]"]
[null,"PTRCORNt7","orn[c] + ptrc[e] <==> orn[e] + ptrc[c]"]
[null,"PTRCt2r","h[e] + ptrc[e] <==> h[c] + ptrc[c]"]
[null,"PROt2r","h[e] + pro-L[e] <==> h[c] + pro-L[c]"]
[null,"PROabc","atp[c] + h2o[c] + pro-L[e] --> adp[c] + h[c] + pi[c] + pro-L[c]"]
[null,"PIabc","atp[c] + h2o[c] + pi[e] --> adp[c] + h[c] + (2) pi[c]"]
[null,"ACMANApts","acmana[e] + pep[c] --> acmanap[c] + pyr[c]"]
[null,"MNLpts","mnl[e] + pep[c] --> mnl1p[c] + pyr[c]"]
[null,"SUCpts","pep[c] + sucr[e] --> pyr[c] + suc6p[c]"]
[null,"GLCpts","glc-D[e] + pep[c] --> g6p[c] + pyr[c]"]
[null,"FRUpts","fru[e] + pep[c] --> f1p[c] + pyr[c]"]
[null,"TREpts","pep[c] + tre[e] --> pyr[c] + tre6p[c]"]
[null,"PROt4","na1[e] + pro-L[e] --> na1[c] + pro-L[c]"]
[null,"RMNt","h[e] + rmn[e] --> h[c] + rmn[c]"]
[null,"TSULabc","atp[c] + h2o[c] + tsul[e] --> adp[c] + h[c] + pi[c] + tsul[c]"]
[null,"SERt2r","h[e] + ser-L[e] <==> h[c] + ser-L[c]"]
[null,"THMabc","atp[c] + h2o[c] + thm[e] --> adp[c] + h[c] + pi[c] + thm[c]"]
[null,"SBTpts","pep[c] + sbt-D[e] --> pyr[c] + sbt6p[c]"]
[null,"SERt4","na1[e] + ser-L[e] --> na1[c] + ser-L[c]"]
[null,"THRt4","na1[e] + thr-L[e] --> na1[c] + thr-L[c]"]
[null,"TAURabc","atp[c] + h2o[c] + taur[e] --> adp[c] + h[c] + pi[c] + taur[c]"]
[null,"THRt2r","h[e] + thr-L[e] <==> h[c] + thr-L[c]"]
[null,"TRPt2r","h[e] + trp-L[e] <==> h[c] + trp-L[c]"]
[null,"Kt2r","h[e] + k[e] <==> h[c] + k[c]"]
[null,"TYRt2r","h[e] + tyr-L[e] <==> h[c] + tyr-L[c]"]
[null,"GLYC3Pabc","atp[c] + glyc3p[e] + h2o[c] --> adp[c] + glyc3p[c] + h[c] + pi[c]"]
[null,"MAN6Pt6_2","man6p[e] + (2) pi[c] --> man6p[c] + (2) pi[e]"]
[null,"G6Pt6_2","g6p[e] + (2) pi[c] --> g6p[c] + (2) pi[e]"]
[null,"FUCPt6_2","fuc1p-L[e] + (2) pi[c] --> fuc1p-L[c] + (2) pi[e]"]
[null,"XTSNt2r","h[e] + xtsn[e] <==> h[c] + xtsn[c]"]
[null,"INSt2r","h[e] + ins[e] <==> h[c] + ins[c]"]
[null,"ADNt2r","adn[e] + h[e] <==> adn[c] + h[c]"]
[null,"CYTDt2r","cytd[e] + h[e] <==> cytd[c] + h[c]"]
[null,"THMDt2r","h[e] + thymd[e] <==> h[c] + thymd[c]"]
[null,"URIt2r","h[e] + uri[e] <==> h[c] + uri[c]"]
[null,"XYLt2","h[e] + xyl-D[e] --> h[c] + xyl-D[c]"]
[null,"XYLabc","atp[c] + h2o[c] + xyl-D[e] --> adp[c] + h[c] + pi[c] + xyl-D[c]"]
[null,"CHLt2r","chol[e] + h[e] <==> chol[c] + h[c]"]
[null,"ADEt2r","ade[e] + h[e] <==> ade[c] + h[c]"]
[null,"RIBabc","atp[c] + h2o[c] + rib-D[e] --> adp[c] + h[c] + pi[c] + rib-D[c]"]
[null,"PSCVT","[c]pep + skm5p <==> 3psme + pi"]
[null,"DHQS","[c]2dda7p --> 3dhq + pi"]
[null,"CHORS","[c]3psme --> chor + pi"]
[null,"DHQD","[c]3dhq <==> 3dhsk + h2o"]
[null,"SHK3Dr","[c]3dhsk + h + nadph <==> nadp + skm"]
[null,"DDPA","[c]e4p + h2o + pep --> 2dda7p + pi"]
[null,"SHKK","[c]atp + skm --> adp + h + skm5p"]
[null,"PPNDH","[c]h + pphn --> co2tot + phpyr"]
[null,"CHORM","[c]chor --> pphn"]
[null,"TRPAS2","[c]h2o + trp-L <==> indole + nh4 + pyr"]
[null,"TRPS2","[c]indole + ser-L --> h2o + trp-L"]
[null,"TRPS3","[c]3ig3p --> g3p + indole"]
[null,"TRPS1","[c]3ig3p + ser-L --> g3p + h2o + trp-L"]
[null,"PRAIi","[c]pran --> 2cpr5p"]
[null,"IGPS","[c]2cpr5p + h --> 3ig3p + co2tot"]
[null,"ANS","[c]chor + gln-L --> anth + glu-L + h + pyr"]
[null,"ANPRT","[c]anth + prpp --> ppi + pran"]
[null,"PPND","[c]nad + pphn + h2o --> 34hpp + co2tot + nadh"]
[null,"TYRTA","[c]akg + tyr-L <==> 34hpp + glu-L"]
[null,"PHETA1","[c]akg + phe-L <==> glu-L + phpyr"]
[null,"BETALDHx","[c]betald + h2o + nad --> glyb + (2) h + nadh"]
[null,"BETALDHy","[c]betald + h2o + nadp --> glyb + (2) h + nadph"]
[null,"HCO3E","[c]co2tot <==> h + hco3"]
[null,"CYANST","[c]cyan + tsul --> h + so3 + tcynt"]
[null,"CAT","[c](2) h2o2 --> (2) h2o + o2"]
[null,"SELNPS","[c]atp + h2o + seln --> amp + pi + selnp"]
[null,"SPODM","[c](2) h + (2) o2- --> h2o2 + o2"]
[null,"ACONMT","[c]acon-T + amet --> aconm + ahcys"]
[null,"THRD_L","[c]thr-L --> 2obut + nh4"]
[null,"ACHBS","[c]2obut + h + pyr + h2o --> 2ahbut + co2tot"]
[null,"ACLS","[c]h + (2) pyr + h2o --> alac-S + co2tot"]
[null,"KARA2i","[c]2ahbut + h + nadph --> 23dhmp + nadp"]
[null,"KARA1i","[c]alac-S + h + nadph --> 23dhmb + nadp"]
[null,"DHAD2","[c]23dhmp --> 3mop + h2o"]
[null,"DHAD1","[c]23dhmb --> 3mob + h2o"]
[null,"ILETA","[c]akg + ile-L <==> 3mop + glu-L"]
[null,"VALTA","[c]akg + val-L <==> 3mob + glu-L"]
[null,"LEUTAi","[c]4mop + glu-L --> akg + leu-L"]
[null,"IPPS","[c]3mob + accoa + h2o --> 3c3hmp + coa + h"]
[null,"IPMD","[c]3c2hmp + nad --> 3c4mop + h + nadh"]
[null,"OMCDC","[c]3c4mop + h + h2o --> 4mop + co2tot"]
[null,"IPPMIa","[c]3c2hmp <==> 2ippm + h2o"]
[null,"IPPMIb","[c]2ippm + h2o <==> 3c3hmp"]
[null,"ATPS4r","adp[c] + (4) h[e] + pi[c] <==> atp[c] + (3) h[c] + h2o[c]","excluded in analysis"]