URL’s of the tools and applications used in this study.


ProtParam:	http://ca.expasy.org/tools/protparam.html
ProtScale:	http://ca.expasy.org/tools/protscale.html
SAPS:		http://www.isrec.isb-sib.ch/software/SAPS_form.html
BLAST:		http://www.ncbi.nlm.nih.gov/BLAST/

ProtFun:	http://www.cbs.dtu.dk/services/ProtFun-2.2/
PSORT:		http://psort.nibb.ac.jp/form.html
ProtCompB:	http://www.softberry.com/berry.phtml?topic=pcompb&group=programs&subgroup=proloc
PRED-CLASS	http://athina.biol.uoa.gr/PRED-CLASS/input.html
SVMProt:	http://jing.cz3.nus.edu.sg/cgi-bin/svmprot.cgi

SignalP:	http://www.cbs.dtu.dk/services/SignalP/
PrediSi:	http://www.predisi.de/index.html
sigcleave:	http://bioweb.pasteur.fr/seqanal/interfaces/sigcleave.html
Phobius:	http://phobius.cgb.ki.se/index.html
SIG-Pred:	http://www.bioinformatics.leeds.ac.uk/prot_analysis/Signal.html
SOSUIsignal:	http://bp.nuap.nagoya-u.ac.jp/sosui/sosuisignal/sosuisignal_submit.html
iPSORT:		http://hc.ims.u-tokyo.ac.jp/iPSORT/index.html#predict

TopPred:	http://bioweb.pasteur.fr/seqanal/interfaces/toppred.html
TMpred:		http://www.ch.embnet.org/software/TMPRED_form.html
PHDhtm:		http://npsa-pbil.ibcp.fr/cgi-bin/npsa_automat.pl?page=/NPSA/npsa_htm.html
TMHMM:		http://www.cbs.dtu.dk/services/TMHMM/
SPLIT:		http://split.pmfst.hr/split/4/
HMMTOP:		http://www.enzim.hu/hmmtop/index.html
MEMSAT:		http://saier-144-37.ucsd.edu/memsat.html
DAS:		http://www.sbc.su.se/~miklos/DAS/maindas.html
TSEG:		http://www.genome.jp/SIT/tsegdir/tseg_exe.html

NPS-consensus secondary structure server:
		http://npsa-pbil.ibcp.fr/cgi-bin/npsa_automat.pl?page=/NPSA/npsa_seccons.html

SMART:		http://smart.embl-heidelberg.de/smart/set_mode.cgi?NORMAL=1
PPSearch:	http://www.ebi.ac.uk/ppsearch/
PSITE:		http://www.softberry.com/berry.phtml?topic=psite&group=programs&subgroup=proloc

SWISS-MODEL:	http://swissmodel.expasy.org//SWISS-MODEL.html
ModWeb:		http://alto.compbio.ucsf.edu/modweb-cgi/main.cgi
GenThreader:	http://bioinf.cs.ucl.ac.uk/psipred/
123D+:		http://123d.ncifcrf.gov/run123D+.html
Phyre:		http://www.sbg.bio.ic.ac.uk/~phyre/

WHATIF:		http://swift.cmbi.kun.nl/WIWWWI/

ProFunc:	http://www.ebi.ac.uk/thornton-srv/databases/ProFunc/
Q-SiteFinder:	http://www.bioinformatics.leeds.ac.uk/qsitefinder/
PINUP:		http://sparks.informatics.iupui.edu/PINUP/
SuMo:		http://sumo-pbil.ibcp.fr/cgi-bin/sumo-welcome

SCRATCH:	http://www.ics.uci.edu/%7Ebaldig/scratch/
ProSAL:		http://xray.bmc.uu.se/sbnet/prosal.html
MetaPP:		http://www.predictprotein.org/newwebsite/meta/submit3.php