SEQUENCES USED IN ANALYSES PRESENTED IN FIGURES 1 (ANIMALS), 2 (FUNGI) and 4 (BIKONTS) ANIMALS: pp. 1 - 34 FUNGI: pp. 35 - 62 BIKONTS: p. 63 - 90 ANIMALS – FIGURE 1 >Homo_sapiens_BC092409_cullin3| . EYLSLFIDDKLKKG----VKGLTEQ-EVETILDKAMVLFRFMQEKDVFER-YYKQHLAR- RLLTNKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFR-DM SISNTTMDEFRQHL---------------------------------------------- --QATGVSLGGVDLTVRVLTTGYWPTQSATP-----------------------KCNIPP APRHAFEIFRRFYLA-------------------------------------KHSGRQLT L-QHHMGSADLNATFYGPVKKEDGSEVGVGGAQ----------------VTGSNTRKHIL QVSTFQMTILMLFNNREK-----YTFEEIQQETDIPERELVRALQSLACGKPTQR-VLTK EPKS-------------KEIENGHIFTVNDQFT-------SKLHRVKIQ--TVAAKQGES DPERK--ETRQKVDD--DRKHEIEAAIVRIMKSR--KKMQHNVLVAEVTQQLKA------ --------RFLPSPVVIKKRIEGLIEREYLARTPED-RKVYTYVA >Xenopus_laevis_BC073186| . EYLSLFIDDKLKKG----VKGLTEQ-EVESILDKAMVLFRFMQEKDVFER-YYKQHLAR- RLLTNKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFR-DM SISNTTMDEFRQHL---------------------------------------------- --QTTGVSLGGVDLTVRVLTTGYWPTQSATP-----------------------KCNIPP SPRHAFEIFRRFYLA-------------------------------------KHSGRQLT L-QHHMGSADLNATFYGAVKKEDGSEVGVGGAQ----------------VTGSNTRKHIL QVSTFQMTILMLFNNREK-----YTFEEIQQETDIPERELVRALQSLACGKPTQR-VLTK EPKS-------------KEIESGHMFTVNDQFT-------SKLHRVKIQ--TVAAKQGES DPERK--ETRQKVDD--DRKHEIEAAIVRIMKSR--KKMQHNVLVAEVTQQLKA------ --------RFLPSPVVIKKRIEGLIEREYLARTPED-RKVYTYVA >Danio_rerio_BC163249.1| . EYLSLFIDDKLKKG----VKGLTEQ-EVESILDKAMVLFRFMQEKDVFER-YYKQHLAR- RLLTNKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFR-DM SISNTTMDEFRQHL---------------------------------------------- --TSTGVSLGGVDLIVRVLTTGYWPTQSATP-----------------------KCNIPP SPRHAFEVFRRFYLA-------------------------------------KHSGRQLT L-QHHMGSADLNATFYGPIKKEDGSDM-VGGAQ----------------VTGSNTRKHIL QVSTFQMTILMLFNNREK-----STFEEIQQETDIPERELVRALQSLACGKPTQR-VLTK EPKS-------------KEIENGHVFTVNDQFT-------SRLHRVKIQ--TVAAKQGES DPERK--ETRQKVDD--DRKHEIEAAIVRIMKSR--KKMQHNVLVAEVTQQLRA------ --------RFLPSPVVIKKRIEGLIEREYLARTPED-RKVYTYVA >Danio_rerio_BC060901| . EYLSLFIDDKLKKG----VKGLTEQ-EVESILDKAMVLFRFMQEKDVFER-YYKQHLAR- RLLTNKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFR-DM SISNTTMDEFRHHL---------------------------------------------- --QTSQVSLCGVDLTVRVLTTGYWPTQSATP-----------------------KCNIPP SPRHAFEVFRRFYLA-------------------------------------KHSGRQLT L-QHHMGSADLNATFYGPIKKEDGSDVGVGGAL----------------LTGSNTRKHIL QVSTFQMTILMLFNNREK-----FTFEEIQQETDIPERELVRALQSLACGKPTQR-VLTK EPKS-------------KEIESGHVFTVNDQFT-------SKLHRVKIQ--TVAAKQGES DPERK--ETRQKVDD--DRKHEIEAAIVRIMKSR--KKMQHNVLVAEVTQQLRA------ --------RFLPSPVVIKKRIEGLIEREYLARTPED-RKVYTYVA >Gasterosteus_aculeatus_BT028614.1| . EYLSLFIDDKLKKG----VKGLTEQ-EVESILDKAMVLFRFMQEKDVFER-YYKQHLGR- RLLSNKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFR-DM SISNTTMDEFRQHI---------------------------------------------- --QTTSASLSGVDLTVRVLTTGYWPTQSATP-----------------------KCTIPP SPRHAFEVFRRFYLA-------------------------------------KHSGRQLT L-QHHMGGADLNATFYGTIKKEDGSEVGVGGAQ----------------VTGSNTRKHIL QVSTFQMTILMLFNNREK-----CTFEEIQQETDIPERELVRALQSLACGKPTQR-VLTK EPKS-------------KEIESGHVFTVNDQFT-------SKLHRVKIQ--TVAAKQGES DPERK--ETRQKVDD--DRKHEIEAAIVRIMKSR--KKMQHNVLVAEVTQQLRA------ --------RFLPSPVVIKKRIEGLIEREYLARTPED-RKVYTYVA >Canis_familiaris_XM_854981.1| . EYLSLFIDDKLKKG----VKGLTEQ-EVETILDKAMVLFRFMQEKDVFER-YYKQHLAR- RLLTNKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFR-DM SISNTTMDEFSS------------------------------------------------ ---TSLELSSGVDLTVRVLTTGYWPTQSATP-----------------------KCNIPP APRHAFEIFRRFYLA-------------------------------------KHSGRQLT L-QHHMGSADLNATFYGPV------------------------------------KKHIL QVSTFQMTILMLFNNREK-----YTFEEIQQETDIPERELVRALQSLACGKPTQR-VLTK EPKS-------------KEIENGHIFTVNDQFT-------SKLHRVKIQ--TVAAKQGES DPERK--ETRQKVDD--DRKHEIEAAIVRIMKSR--KKMQHNVLVAEVTQQLKA------ --------RFLPSPVVIKKRIEGLIEREYLARTPED-RKVYTYVA >Branchiostoma_floridae_XM_002202899.1| . EYLSLFIDDKLKKG----VKGLTEQ-EIENILDKTMVLFRYLQEKDVFER-YYKQHLAR- RLLMNKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFK-DM SISNSLMDDFKQHL---------------------------------------------- --QNTGTTLSGIDLSVRVLTTGFWPTQSSSP-----------------------KCNIPV QARNAFETFKRFYLV-------------------------------------KHSGRQLT L-QHHMGSADLNATFYGPRKE----------------------------GGGSNARKHIL QVSTFQMCVLMLFNNRDK-----LTYEEIQSETDIPDRDLTRALQSLALGKAQQR-VLVK EPKV-------------KEIEPSHQFYINDQFT-------SKLHRVKIQ--TVAAK-GES DPERK--ETRNRVDE--DRKHEIEAAIVRIMKSR--KRMQHNVLVAEVTQQLKA------ --------RFLPSPVVIKKRMEGLIEREYLARAPED-RKVYTYVA >Tribolium_castaneum_XM_962327.1| . EYLSLFIDDKLKKG----VKGMSEQ-EIELVLDKSMVLFRFLQEKDVFER-YYKQHLAK- RLLLNKS----------------VSDDWEKNMISKLK--TECGC--QFTSKLEGMFK-DM TVSNTIMDEFKDHI---------------------------------------------- --TKTESSLCGVDLFMRVLTTGFWPTQSATP-----------------------KCHIPA VPLAAFECFSRFYLA-------------------------------------KHSGRQLT L-QPQLGNADLNAIFFGPKKEDPDKDGACSSTSSI--------------SPRTGPRKHII QVSTYQMVVLMLFNNHEK-----LTYEEILNESDIPERDLIRALQSLAMGKATQR-ILIK NPRT-------------KEIESNHEFYVNDSFT-------SKLHRVKIQ--TVAAK-GES EPERR--ETRNKVDE--DRKHEIEAAIVRIMKSR--KRMPHNILVTEVTEQLKS------ --------RFLPSPVIIKKRIEGLIEREYLARTPED-RKVYTYVA >Nasonia_vitripennis_XM_001606564.1| . EYLSLFIDDKLKKG----LKGMTEQ-EIEGILDKTMVLFRFLQEKDVFER-YYKQHLAK- RLLLNKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFK-DI TVSNTIMEEFKEHT---------------------------------------------- --LANGMTLSGVDLSVRVLTTGFWPTQAATP-----------------------KCSMPS APRNAFDAFRRFYLG-------------------------------------KHSGRQLT L-QPQLGSADLNATFYGPRREENMPECSSTSPGFGNNGNGQRS------SGTITTRKHII QVSTYQMCVLMLFNNREK-----LTYEEIQNETDIPERDLIRALQSLAMGKATQR-VLLK YPRT-------------KEIEPSHSFCVNDNFS-------SKLHRVKIQ--TVAAK-GEC EPERK--ETRSKVDE--DRKHEIEAAIVRIMKAR--KRMAHNILVTEVTDQLRA------ --------RFLPSPVIIKKRLENLIEREYLARTPED-RKVYTYVA >Apis_mellifera_XM_625076.2| . EYLSLFIDDKLKKG----VKGMTEQ-EIEGILDKTMVLFRFLQEKDVFER-YYKQHLAK- RLLLNKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFK-DI TVSNTIMDEFKDHV---------------------------------------------- --LTSNTNLHGVDISVRVLTTGFWPTQSATP-----------------------KCSMPA APRDAFDAFRRFYLA-------------------------------------KHSGRQLT L-QPQLGSADLNAVFHGPRREESSCGGLDTPSSSS--------------SSCGNTRKHII QVSTYQMCVLMLFNKREK-----LTYEEIQGETDIPERDLVRALQSLAMGKATQR-VLLK HPRT-------------KEIEPSHYFCVNDSFT-------SKLHRVKIQ--TVAAK-GES EPERR--ETRNKVDE--DRKHEIEAAIVRIMKDR--KRMPHNILVTEVTEQLRG------ --------RFLPSPVIIKKRIEGLIEREYLARTPED-RKVYTYVA >Strongylocentrotus_purpuratus_XM_001178186.1| . EYLSLFIDDKLKKG----VKGLSEQ-EVEAILDKSMVLFRFLQEKDVFER-YYKQHLAK- RLLLNKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFK-DM TLSNTFMDEFKTHV---------------------------------------------- --QSASINMFGVDLNVRVLTTGFWPTQSATP-----------------------QCNVPT QARNAFEAFKKFYLT-------------------------------------KHTGRQIS L-QPQLGSADLHATFHGGKKVGFIGFY----------------------PMGSDERRHII QVSTYQMCVLMLFNVKEQ-----WTYEEMCSETDIPSKDLIRALQSLALGKPTQR-ILVK EPKG-------------KEIENPHMFSVNDAFT-------SKLFRVKIQ--TVAAK-GES EPERK--ETRTRVDE--DRKHEIEAAIVRIMKSR--KKMQHNVLVAEVTEQLKS------ --------RFLPSPVVIKKRIESLIEREYLARAPED-R------- >Strongylocentrotus_purpuratus_XM_789962.2| . EYLSLFIDDKLKKG----VKGLSEQ-EVEAILDKSMVLFRFLQEKDVFER-YYKQHLAK- RLLLNKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFK-DM TLSNTFMDEFKTHV---------------------------------------------- --QSASINMFGVDLNVRVLTTGFWPTQSATP-----------------------QCNVPT QARNAFEAFKKFYLT-------------------------------------KHTGRQIS L-QPQLGSADLHATFHGGKKVAKGGAQ----------------------GPVSQERRHII QVSTYQMCVLMLFNVKEQ-----WTYEEMCSETDIPSKDLIRALQSLALGKPTQR-ILVK EPKG-------------KEIENPHMFSVNDAFT-------SKLFRVKIQ--TVAAK-GES EPERK--ETRTRVDE--DRKHEIEAAIVRIMKSR--KKMQHNVLVAEVTEQLKS------ --------RFLPSPVVIKKRIESLIEREYLARAPED-R------- >Strongylocentrotus_purpuratus_XM_001178067.1| . EYLSLFIDDKLKKG----VKGLSEQ-EVEAILDKSMVLFRFLQEKDVFER-YYKQHLAK- RLLLNKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFK-DM TLSNTFMDEFKTHV---------------------------------------------- --QSASINMFGVDLNVRVLTTGFWPTQSATP-----------------------QCNVPT QARNAFEAFKKFYLT-------------------------------------KHTGRQIS L-QPQLGSADLHATFHGGKKVD---------------------------GGKHEERRHII QVSTYQMCVLMLFNVKEQ-----WTYEEMCSETDIPSKDLIRALQSLALGKPTQR-ILVK EPKG-------------KEIENPHMFSVNDAFT-------SKLFRVKIQ--TVAAK-GES EPERK--ETRTRVDE--DRKHEIEAAIVRIMKSR--KKMQHNVLVAEVTEQLKS------ --------RFLPSPVVIKKRIESLIEREYLARAPED-R------- >Nematostella_vectensis_XM_001627280.1| . EFLSLFIDDKLKKG----VKGYSEQ-EVEVVLDKCMVLFRFLQEKDVFER-YYKQHLAK- RLLLQKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFK-DM TVSHTTNEEFRQHL---------------------------------------------- --SNSQINLLGVDLIVRVLTTGFWPTQSGNH-----------------------KCNVPP QAQHAFDCFKRFYLG-------------------------------------NHSGRQLT L-QPQLGTAELNATFPPVKKE----------------------------GASLGQRKHIF QMSSYQMCILMLFNSQER-----WTYEDILQQTLIPERDLNRALQSLACGKATQR-VLSK EPKG-------------KDITATDVFSVNDLFT-------SKLHRVKIQ--TVLAK-GES EPERK--ETRTKVDE--DRKHEIEAAIVRIMKAR--KKRPHNLLVAEVTEQLKA------ --------RFLPSPQVIKKRIEGLIEREYLARTPED-RKVYLYVA >Aedes_aegypti_XM_001652545.1| . EYLSLFIDDKLKKG----CKGMSEQ-EIETILDKTMVLFRYLLEKDVFER-YYKAHLAK- RLLLNKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFK-DM SVSNTVMEEFKNHI---------------------------------------------- --SNDPSALDGVELSVRILTTGFWPTQSATP-----------------------NCNIPL APRRAFETFKRFYLA-------------------------------------KHSGRQLT L-QPQLGTVYMNAEFYGVKAEKEPVEGGCSSTAAVAGSSAPS-------VSLGAPRKHVL QLSTYQMCVLMLFNNRER-----LTYDEIQQETDIPGKDLIRALQSLSMGKQQQR-LLVR TPKS-------------KDIEPTNVFYVNDAFV-------SKFHKVKIQ--TVAAK-GES EPERK--ETRSKVDE--DRKHEIEAAIVRIMKAR--KKMAHNLLVSDVTTQLKS------ --------RFMPSPVIIKKRIEGLIEREYLARTPED-RKVYVYLA >Culex_quinquefasciatus_XM_001861301.1| . EYLSLFIDDKLKKG----CKGMSEQ-EIETILDKTMVLFRYLLEKDVFER-YYKAHLAK- RLLLNKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFK-DM SVSNTVMEEFKNHI---------------------------------------------- --SNDPSALDGVELSVRILTTGFWPTQSATP-----------------------NCNIPL APRRAFETFKRFYLA-------------------------------------KHSGRQLT L-QPQLGTVYMNAEFYGVKAEKE------------------------------------S AEGTAAMCVLMLFNNRER-----LSYDEIQQETDIPGKDLIRALQSLSMGKQQQR-LLVR TPKT-------------KDIEPTNVFYVNDAFV-------SKFHKVKIQ--TVAAK-GES EPERK--ETRSKVDE--DRKHEIEAAIVRIMKAR--KKMAHNLLVSDVTTQLKS------ --------RFMPSPVIIKKRIEGLIEREYLARTPED-RKVYVYLA >Anopheles_gambiae_AAAB01008964.1| . EYLSLFIDDKLKKG----CKGMSEQ-EIETILDKTMVLFRYLQEKDVFER-YYKAHLAK- RLLLNKS----------------VSDDSEKNMISKLK--TECGC--QFTSKLEGMFK-DM SVSNTVMEEFKNHI---------------------------------------------- --NNDNSALEGVELTVRILTTGFWPTQSVTP-----------------------NCNIPA APRKAFETFKRFYLA-------------------------------------KHSGRQLT L-QPQLGTVYMNAEFYGVKAEKEKTEGNCSSTAPSAGSSSAPTGGA---ASLDAPKRHVL QLSTYQMCVLMLFNNRER-----MTYEDIQQETDIPSKDLIRALQSLSMGKQQQR-LLVR TPKTS------------KEIVSTDEFYVNDAFV-------SKFHRVKIQ--TVAAK-GES EPERK--ETRSKVDE--DRKHEIEAAIVRIMKAR--KRMPHNLLVSDVTSQLKS------ --------RFLPSPVIIKKRIEGLIEREYLARTPED-RKIYVYLA >Drosophila_grimshawi_XM_001993299.1| . EYLSLFIDDKLKKG----GKGMSEQ-EIETILDKTMVLFRFLLEKDVFER-YYKTHLAK- RLLLNKS----------------VSDDFEKNMISKLKASTECGC--QFTSKLEGMFK-DM SVSNTIMDEFKNYV---------------------------------------------- --NNNSFSLSGVELTVRILTTGFWPTQTATP-----------------------NCNIPS APREAFEVFKKFYLD-------------------------------------KHSGRQLT L-QPQMGTAYINAVFYGRKAN-DSDKDKDGPSSSSSGC-----------AVPTTTRKHIL QVSTYQMCVLLLYNNRDV-----LTYDDIHQETDIPERELVRALQSLSMGKPAQR-LLVR NSKTKT-----------KDIEPSDEFYVNDAFV-------SKFHRVKIQ--TVAAK-GES EPERK--ETRGKVDE--DRKHEIEAAIVRIMKAR--KRMAHNLLVSDVTSQLKS------ --------RFLPSPVFIKKRIEGLIEREYLARTPED-RKVYIYLA >Drosophila_mojavensis_XM_002003366.1| . EYLSLFIDDKLKKG----GKGMSEQ-EIETILDKTMVLFRFLLEKDVFER-YYKTHLAK- RLLLNKS----------------VSDDFEKNMISKLK--TECGC--QFTSKLEGMFK-DM SVSNTIMDEFKSYV---------------------------------------------- --NNNSLSLSGVELTVRILTTGFWPTQTATP-----------------------NCNIPS APREAFEVFKKFYLD-------------------------------------KHSGRQLT L-QPQMGTAYINAVFYGRKAN-DSDKDKDGPSSSSSGC-----------PVPTTTRKHIL QVSTYQMCVLLLFNNRDL-----LTYDDIHQETDIPERELVRALQSLSMGKPAQR-LLVR NSKTKT-----------KDIEPSDEFYVNDAFV-------SKFHRVKIQ--TVAAK-GES EPERK--ETRGKVDE--DRKHEIEAAIVRIMKAR--KRMAHNLLVSDVTSQLKS------ --------RFLPSPVFIKKRIEGLIEREYLARTPED-RKVYIYLA >Drosophila_persimilis_XM_002021570.1| . EYLSLFIDDKLKKG----GKGMSEQ-EIESILDKTMVLFRFLLEKDVFER-YYKTHLAK- RLLLNKS----------------VSDDFEKNMISKLK--TECGC--QFTSKLEGMFK-DM SVSNTIMDEFKNYV---------------------------------------------- --VNNNLSLVGVELTVRILTTGFWPTQTATP-----------------------NCNIPV APREAFEIFKSFYLN-------------------------------------KHSGRQLT L-QPQMGTSYINAVFYGRKAA-DSDKDKDAPSSSSNGC-----------TVPTTTRKHIL QVSTYQMCVLLLFNNRDV-----LTYDDIQQETDIPGRELVRALQSLSMGKPAQR-LLVR NSKTKT-----------KEIEPTDEFYVNDAFV-------SKFHRVKIQ--TVAAK-GES EPERK--ETRGKVDE--DRKHEIEAAIVRIMKAR--KRMAHNLLVSDVTTQLKS------ --------RFLPSPVFIKKRIEGLIEREYLQRSPED-RKVYIYLA >Drosophila_willistoni_XM_002066343.1| . EYLSLFIDDKLKKG----GKGMSEQ-EIETILDKTMVLFRFLLEKDVFER-YYKTHLAK- RLLLNKS----------------VSDDFEKNMISKLK--TECGC--QFTSKLEGMFK-DM SVSNTIMDEFKGFV---------------------------------------------- --NNNNLSLGGVELTVRILTTGFWPTQTATP-----------------------NCNIPS APREAFEIFKNFYLN-------------------------------------KHSGRQLT L-QPQMGTAYINAVFYGRKTANESEKDKDAPSSSSSGGT----------TGPTTTRKHIL QVSTYQMCVLLLFNNRDI-----LTYDDIHQETDIPERELVRALQSLSMGKPAQR-LLVR NSKTKT-----------KDIEPTDEFYVNDAFV-------SKFHRVKIQ--TVAAK-GES EPERK--ETRGKVDE--DRKHEIEAAIVRIMKAR--KRMAHNLLVSDVTSQLKS------ --------RFLPSPVFIKKRIEGLIEREYLQRSAED-RKVYNYLA >Drosophila_ananassae_XM_001962223.1| . EYLSLFIDDKLKKG----GKGMSEQ-EIESILDKTMVLFRFLLEKDVFER-YYKTHLAK- RLLLNKS----------------VSDDFEKNMISKLK--TECGC--QFTSKLEGMFK-DM SVSNTIMDEFKNFV---------------------------------------------- --NNNNLSLGGVELTVRILTTGFWPTQTATP-----------------------NCNIPA APREAFDIFKNFYLN-------------------------------------KHSGRQLT L-QPQMGTAYINAVFYGRKAA-DTEKDKDAPSSSSSGC-----------AVPTTTRKHIL QVSTYQMCVLLLFNNRDV-----LTYDDIHQETDIPERELVRALQSLSMGKPAQR-LLVR NSKTKT-----------KDIEPTDEFYVNDAFV-------SKFHRVKIQ--TVAAK-GES EPERK--ETRGKVDE--DRKHEIEAAIVRIMKAR--KRMAHNLLVSDVTSQLKS------ --------RFLPSPVFIKKRIEGLIEREYLQRSPED-RKVYNYLA >Drosophila_melanogaster_NM_165110.1| . EYLSLFIDDKLKKG----GKGMSEQ-EIESILDKTMVLFRFLLEKDVFER-YYKTHLAK- RLLLNKS----------------VSDDFEKNMISKLK--TECGC--QFTSKLEGMFK-DM SVSNTIMDEFKNFV---------------------------------------------- --NNNNLSLGGVELTVRILTTGFWPTQTATP-----------------------NCNIPA APREAFDIFKNFYLN-------------------------------------KHSGRQLT L-QPQMGTAYINAVFYGRKAV-ESEKDKDAPSSSSSGC-----------GVPTTTRKHIL QVSTYQMCVLLLFNNRDV-----LTYDDIHQETDIPERELVRALQSLSMGKPAQR-LLVR NSKTKT-----------KDIEPTDEFYVNDAFN-------SKFHRVKIQ--TVAAK-GES EPERK--ETRGKVDE--DRKHEIEAAIVRIMKAR--KRLAHNLLVSDVTSQLKS------ --------RFLPSPVFIKKRIEGLIEREYLQRSPED-RKVYNYLA >Ciona_intestinalis_AK114786.1| . EYLSLFIDDKLKKG----IKMLSEQ-EVEVVLDKTMSLFRFLQEKDVFER-YYKQHLGR- RLLTNKS----------------ISDDSEKNMITKLK--NECGC--QFTSKLEGMFK-DM HVSSTTNDDFKKHV---------------------------------------------- --QSTSTSLQGVDLTVQVLTTGCWPTQASTP-----------------------TCNLPA APRHAFDVFRRFYLG-------------------------------------KHSGRQLT L-QHHRGAADMNASFFAAAKPGASNEGESA-------------------SVKPTTRRHIL QVSTFQMVVLMLFNDREK-----WLFEEIQQETEIPVKDLSRALQSLACGKTNQR-VLQK DPKG-------------KEIEKGNVFTVNDNFS-------SKLHRVKIQ--TVAQKQGES DPERK--ETRTKVQE--DRRHEIEAAIVRIMKSR--KEMQHNLLIAEVTSQLKH------ --------RFLPSPVIIKRRIESLIEREYLSRSNTD-RKVYIYVA >Acyrthosiphon_pisum_XM_001947463.1| . EYMSLFIDDKLKKG----VRGIDEN-DLEPVLDKAMVLFRFLQDKDVFET-YYKQHLAK- RLLLNKS----------------VSDDNEKNMISKLK--TECGC--QFTSKLEGMFK-DM SLSNTIMESFKLYL---------------------------------------------- -SNSPASNCNNIDLSVRVLTTGFWPLPTTTP-----------------------KCNVPS IARLAYEEFRTFYLG-------------------------------------KHNGRQLR L-QPQLGSADLTAIFNDNRRENSATSVISSNGSGSTVVSTSSNSGTSVNNANSSARKHIF QVSTYQMAILMLFNSYEK-----MTMEMIMNETDINEKDLTRALQSLAMGKPSQR-VLLK SPKT-------------KEIEPHHEFSINESYT-------SKLYRVKIQ--SITTK-GEN EPERR--KTKDKVEE--DRKHEIEAALVRIMKAR--KTLTHNTLIMEVTEQLRS------ --------RFMPSPVLIKKRIECLIEREYLARTPED-RNTYNYVA >Acyrthosiphon_pisum_XM_001952349.1| . EYLSLFVDEKLKKG----VRGLTEN-DVEVVLDKAMVIFRFLQEKDVFER-YYKQHLAK- RLLLNKS----------------VSNDNEKNMISKLK--TECGC--QFTSKLEGMFK-DM SVSNTIMEEFKEYA---------------------------------------------- -AKSNNPFLHAVDLTVRVLTTGFWPTH-ALS-----------------------KCNVPL VPRSAFAEYRNFYLG-------------------------------------KHNGRQLT L-QPQLGSADLNAVFYGSRRPDNELLTTVSISANS--------------LSSSSVRRHII QVSTYQMCILLMFNTHEK-----LTFEDIRSETDIPDKDLIRALQSLALGKPSQR-ILLK TPKC-------------KEIELTHEFCVNELFT-------SKLHRVKIQ--TVAAK-GET EPERK--ETRSKVDE--DRKHEIEAAIVRVMKSR--KKLIHNTLVLEVVEQLKV------ --------RFLPSPVIIKKRIEGLIEREYLARSTED-RKTYLYVA >Trichoplax_adhaerens_XM_002107564.1| . EYLSLYIDDKLKKG----TKGLSDQ-EIELLLEKTMVLFRYLQDKDVFEK-YYKQHLAK- RLLLGKS----------------SSNEMENSMIFKLK--SECGC--QFTSKLEGMFK-DM SVSETVMEKFKKHL---------------------------------------------- ---DSSQTTINFDLNIRVLTAGFWPSQLSSN-----------------------QCNIPT EISTCYDAFQSFYLG-------------------------------------GHNGRKLV L-QAQLGFADLHATFFGSKKPD---------------------------SVKLETRNHIL QVSTFQMVILLLFNSKEK-----LSFEELKIATNIPDRDLIRALQSLACGKTSQR-ILTK NPKS-------------KEIGPADEFIVNDNFT-------SKLVRVKIQ--T-------- ------------------------AAIIRIMKAR--KQLHHSALVVETTELLTA------ --------RFMPHPMVIKKRIESLIEREYLRRTD-D-RKMYSYVA >Tetraodon_nigroviridis_CAAE01014992.1| . EYLSLFIHDKLTKG----TKQLTEQ-EVESYLDKALMLFKILQEKDMFEK-YYKQHLSY- RLLSNMS----------------VSEHTEKSMILRLK--VECGF--QFTAKLEGMFK-DM SISTTTMEEFLSHI---------------------------------------------- --QTVPISLSGLNLTVKVLTSGVWPTQPQAP-----------------------KCSIPS IPSTAFEVFRRFYLA-------------------------------------KHNGRQLM L-QYHMGWADVNATFYGSLQKVDDPESNA--------------------GGAQVTRKHIL QVSTFQMTILMLFNNRET-----FTFQEIQQETDIPDNDLLRALLPLYWGKPSQR-VLVK EPDC-------------KQIKKEDIFTVNDEFS-------SKKYKVKMQ--TGFCDQATS CPEGE--KTRYRVDQ--ERKLQIEAAIVRIMKSK--NRLHHRALVTEATQQLQG------ --------SFQPSSAVVKTCIETLIEKEFIARTPED-ERAYVYIA >Caenorhabditis_elegans_U58085.1| . EFVALYMDDMLRSG----LKCVSDA-EMDNKLDNVMILFRYLQEKDVFEK-YFKQYLAK- RLLLDKS----------------CSDDVEKALLAKLK--TECGC--QFTQKLENMFR-DK ELWLTLATSFRDWR---------------------------------------------- ---EAQPTKMSIDISLRVLTAGVWPTVQCNP------------------------VVLPQ ELSVAYEMFTQYYTE-------------------------------------KHTGRKLT I-NTLLGNADVKATFYPPPKASMSNEENGPGPSGSGES-----------MKERKPEHKIL QVNTHQMIILLQLNHHNR--ISCQHEQQLMDELKIPERELKRNLQSLALGKASQR-ILVR KNKGK------------DAIDMSDEFAVNDNFQ-------SKLTRVKVQ--MVTGK-VES EPEIR--ETRQKVED--DRKLEVEAAIVRIMKAR--KKLNHNNLVAEVTQQLRH------ --------RFMPSPIIIKQRIETLIEREYLARDEHD-HRAYQYIA >Brugia_malayi_XM_001892856.1| . ---------------------MNES-EQESLQDKSMVLFRFLQEKDVFER-YYKSHLAK- RLLLQKS----------------MSDDAEKAMVSKLK--TECGC--QFTSKLEGMFK-DI ELSNILMGDFRDYK---------------------------------------------- --ERAEIAHDSVDITVRVLTSGYWPTQAAPD------------------------CVLPP VAAQAFESFRTFYLS-------------------------------------KHNGRKIS L-NPMLGHADVKAVFYGTNANAEELSQQESDLAGPSV------------APRGKEEYKIL TVSTYQMCVLLRFNNKSK-----ITFEELAAETQIPDKELKRSLLSLAMGKPTQR-ILCR KGHG-------------REIENSDEFWVNDAFT-------SKLTRIKIQ--MVSGR-AEA EPERK--ETRSRIDE--DRKHEVEAAVVRVMKAR--KKLLHNVLVAEVTQQLKH------ --------RFMPNPQLIKKRIESLIERDYLARDKND-HRCYEYVA >Caenorhabditis_elegans_NM_063124.3_CUL4 . ELISKHFHTLLHSS----NKNVSDDTTLDQMVDEAIVLFRYLRGKDVFEA-YYKRGLAK- RLFLERS----------------ASVDAEKMVLCKLK--TECGS--AFTYKLEGMFK-DM DASENYGRLFNQYL---------------------------------------------- ----EHMNKEKANFTARVITPEYWPTYDTYE------------------------INIPK EMRDTLTDYQDFYRV-------------------------------------QHGNRNVK W-HHGLASAVISASFRPG-------------------------------------CKKEL IATMYQTVILLLFNKCET-----WTVAEIVEHTKILEIEVVKNVLALLGGRDKPK-VLQR VEGGGSEKKEGT-----VENLKNEKFVVNSKFT-------EKRCRVRIA----QVNIKTA VEETK--EVKEEVNS--DRQYKIDAAVVRIMKAR--KQLNHQTLMTELLQQL-------- --------RFPVSTADIKKRLESLIEREYISRDPEE-ASSYNYVA >Tribolium_castaneum_XM_001811585.1| . --LAKYLDVKLRS------KDITDE-ELEVVLTKVIKLFKHVQGKDIFEA-FYKKLLAK- RLLLGKS----------------ANQDAENSMISKLR--DECGS--AFTSNIEGMFQ-DI NLSKSINNSFKQKV---------------------------------------------- ---RNQENGFTSEFSVNVLTSSYWPNYPNYA------------------------VNLPC ELVTYQQSFQKFYLS-------------------------------------NHSGRKLL W-QPSLTHCLLKASFECG--------------------------------------VKEL QVSLFQTVVLLLFNASPE-----IAFKEIQEATSLDGGELKRTLLSLVYGKAR---ILLK TPKT-------------KEIEDDDVFVFNNKFT-------DKLFRVKIN----QIQLQDS PEDEK--ETEKNVLV--DRQFQIDAAIVRIMKSK--KTIKHYMLVRELYKVL-------- --------DIPVNQTDLKKRIELLIEREYMERDKDN-KSTYIYIA >Trichoplax_adhaerens_XM_002112143.1| . ELIAKYIDMKLRAG----NKEATDE-ELDKILDKIMVMFRFIQGKDVFEA-FYKKDLAK- RLLVGRS----------------ASVDAEMSMLLKLK--QECGA--GFTSKLEGMFK-DI EHSKELMPHYKQYL---------------------------------------------- ---NNQKIGHNLDMTVNVLMTSNWPTYHPMD------------------------VILPE YMISYQKHFQQFYLS-------------------------------------KHSGRKLQ W-ISTLGHCVVAANFPLG--------------------------------------KKDI VVSLLQTLVLLQFNKEDE-----ISFLDLKQRTGIDDADMRRTLQSLACGKVR---VLHK KPKG-------------KEVEDNDVFAYVSDFK-------HKQFHIKIN----QVQMKET LEENI--NTTERVFQ--DRQYQIDAAIVRIMKTR--KTLSHALLVTAVYEQL-------- --------KFPIKPSDLKKRIESLIERDYMERDEDD-AYQYHYVA >Ciona_intestinalis_XM_002130043.1| . ELIAKYVDQRMKSG----NKEATEV-ELDRTLDQIMMLFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--QECGG--MFTGKLEGMFN-DI SHSKELMAQYRQHV---------------------------------------------- -TTKKEGKVPNIDMSVNILTMGYWPTYPPME------------------------VQLPS YLVKLQDSFKDFYLS-------------------------------------KHSGRKLS F-RASLGHCVLKSKFKNG--------------------------------------NKEL QVSQFQALVLLLYNEATC-----FSFLQIKSDTQIEDSELRRTLQSLACGKAR---ILTK SPKG-------------KDVNDGDNFNLNTEFK-------HKLIRIKIN----QIQLKES VEENT--DTTERVFQ--DRQYQIDAAIVRTMKTR--KTLSHQLLLTELYDQL-------- --------KFPLKATDIKKRIESLIERDYMERDKDN-TTQYHYMA >Drosophila_melanogaster_BT050475.1| . ELIAKYVDMKLRSG----NKGTTDE-ELEKTLDKIMVLFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDSEKSMLSKLK--QECGG--GFTSKLEGMFK-DM ELSRDINIAFRGHA---------------------------------------------- --LSNNRDVHNLDLCVSILTMGYWPTYAPTE------------------------VTMPP QFINPQQIFNKFYLE-------------------------------------KHSGRKLQ W-QPTLGNCMLRAQFDAG--------------------------------------PKEL LVSLFQALVLLLFNDKPV-----LSYEEILAATLIEDGELRRTLQSLACGRAR---VITK TPKG-------------REILDGDQFDFNNEFT-------NKLFRIKIN----QIQMKET NEEQK--ATEERVFQ--DRQYQIDAAIVRIMKMR--KTLSHNLLITELFNQL-------- --------TFPVKPADLKKRIESLIDRDYMERDKDN-QNQYNYVA >Drosophila_erecta_AAPQ01007360.1| . --LAKYVDMKLRSG----NKGTTDE-ELEKTLDKIMVLFRFIHGKDVFEA-FYKKVLAK- RLLVGKS----------------ASVDSEKSMLSKLK--QECGG--GFTSKLEGMFK-DM ELSRDINIAFRGHA---------------------------------------------- --LSNNRDVHNLDLCVSILTMGYWPTYAPTE------------------------VTMPP QFINPQQIFNKFYLE-------------------------------------KHSGRKLQ W-QPTLGNCMLRAQFDAVTKTAHNVSYAVAILTFVLQG------------------PKEL LVSLFQALVLLLFNDKPV-----LSYEEILAATLIEDGELRRTLQSLACGRAR---VITK TPKG-------------REILDGDQFDFNNEFT-------NKLFRIKIN----QIQMKET NEEQK--ATEERVFQ--DRQYQIDAAIVRIMKMR--KTLSHNLLITELFNQL-------- --------TFPVKPADLKKRIESLIDRDYMERDKDN-QNQYNYVA >Drosophila_pseudoobscura_XM_001360883.2| . ELIAKYVDMKLRSG----NKGTTDE-ELEKTLDKIMVLFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDSEKSMLSKLK--QECGG--GFTSKLEGMFK-DM ELSRDINTAFRGHA---------------------------------------------- --LSNNRDVHNLDLCVSILTMGYWPTYAPTE------------------------VTMPP QLINPQQIFNKFYLE-------------------------------------KHSGRKLQ W-QPTLGNCMLRAQFEAG--------------------------------------PKEL LVSLFQALVLLLFNDKPV-----LSYEEILAATMIEGGELRRTLQSLACGRAR---VITK TPKG-------------REIEDGDQFDFNNEFT-------NKLFRIKIN----QIQMKET NEEQK--ATEERVFQ--DRQYQIDAAIVRIMKMR--KTLSHNLLITELFNQL-------- --------TFPVKPADLKKRIESLIDRDYMERDKDN-QNQYNYVA >Drosophila_willistoni_XM_002074561.1| . ELIAKYVDMKLRSG----NKGTTDE-ELEKTLDKIMVLFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDSEKSMLSKLK--QECGG--GFTSKLEGMFK-DM ELSRDINTAFRGHA---------------------------------------------- --LSNNRDVHNLDLCVSILTMGNWPTYPPTE------------------------VTMPP QFINPQQIFNKFYLE-------------------------------------KHSGRKLQ W-QPTLGNCMLRAQFDAG--------------------------------------PKEL MVSLFQALVLLLFNDKPT-----LGYEEILAATSIEDGELRRTLQSLACGRAR---VITK TPKG-------------RDIEDGDQFDFNNEFT-------NKLFRIKIN----QIQMKET NEEQK--ATEERVFQ--DRQYQIDAAIVRIMKMR--KTLSHNLLITELFNQL-------- --------TFPVKPADLKKRIESLIDRDYMERDKDN-QNQYNYVA >Drosophila_ananassae_XM_001960988.1| . ELIAKYVDMKLRSG----NKGTTDE-ELEKTLDKIMVLFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDSEKSMLSKLK--QECGG--GFTSKLEGMFK-DM ELSRDINIAFRGHA---------------------------------------------- --LSNNRDVHNLDLSVSILTMGYWPTYAPTE------------------------VTMPP QFINPQQIFNKFYLE-------------------------------------KHSGRKLQ W-QPTLGNCMLRAQFDAG--------------------------------------PKEL MVSLFQALVLLLFNDKTA-----LSYEEILAATSIEDGELRRTLQSLACGRAR---VITK TPKG-------------RDIEDGDQFDFNDEFT-------NKLFRIKIN----QIQMKET NEEQK--ATEERVFQ--DRQYQIDAAIVRIMKMR--KTLSHNLLITELFNQL-------- --------TFPVKPADLKKRIESLIDRDYMERDKDN-QNQYNYVA >Drosophila_grimshawi_XM_001987369.1| . ELIAKYVDMKLRSG----NKGTTDE-ELEKTLDKIMVLFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDSEKSMLSKLK--QECGG--GFTSKLEGMFK-DM ELSRDVNLAFRGHA---------------------------------------------- --LSNDRDVTNLDLTVSILTMGYWPTYTPTE------------------------VTMPP QFINPQQIFNKFYLE-------------------------------------KHSGRKLQ W-QPTLGNCVLRASFDAG--------------------------------------PKEL LVSLFQGLVLLLFNDKPM-----LSYEEILAATSIEDGELRRTLQSLACGRAR---VITK TPKG-------------RDIEDKDQFDFNNEFI-------NKLFRIKIN----QIQMKET NEEQK--ATEERVFQ--DRQYQIDAAIVRIMKMR--KTLSHNLLITELFNQL-------- --------TFPVKPADLKKRIESLIDRDYMERDKDN-QNQYNYVA >Drosophila_mojavensis_XM_002005046.1| . ELIAKYVDMKLRSG----NKGTTDE-ELEKTLDKIMVLFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDSEKSMLSKLK--QECGG--GFTSKLEGMFK-DM ELSRDVNLAFRGHT---------------------------------------------- --LSNDRDVTNLDLTVSILTMGYWPTYAPTE------------------------VTMPP QFINPQQIFNKFYLE-------------------------------------KHSGRKLQ W-QPTLGNCVLRAHFDAG--------------------------------------PKEL MVSLFQALVLLLFNDKPT-----LSYEEILAATNIEDGELRRTLQSLACGRAR---VITK TPKG-------------RDIEDRDQFDFNNEFV-------NKLFRIKIN----QIQMKET NEEQK--ATEERVFQ--DRQYQIDAAIVRIMKMR--KTLSHNLLITELFNQL-------- --------TFPVKPADLKKRIESLIDRDYMERDKDN-QNQYNYVA >Apis_mellifera_XM_392800.3 . ELIAKFVDCKLRAG----NKEATEE-ELERLLDKIMVLFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--QECGG--GFTSKLEGMFK-DM ELSKDINIAFKQYA---------------------------------------------- GNLQSELSASNLDLTVSILTMGYWPTYPVME------------------------VTLPP EMVQYQDVFNKFYLG-------------------------------------KHSGRKLQ W-QPTLGHCVLKAWFNQG--------------------------------------NKEL QVSLFQALVLILFNDADN-----LSLEDIKAATNIEDGELRRTLQSLACGKAR---VLQK NPRG-------------RDVADNDRFVFNADFT-------NKLFRIKIN----QIQMKET NEEQK--ATEERVYQ--DRQYQIDAAIVRIMKMR--KTLSHNLLISELYNQL-------- --------KFPVKPADLKKRIESLIDRDYMERDKDN-ANEYNYVA >Nasonia_vitripennis_XM_001603471.1| . ELIAKFVDCKLRAG----NKEATEE-ELERLLDKIMVLFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--QECGG--GFTSKLEGMFK-DM ELSKDINIAFKQYS---------------------------------------------- GNLQNELIASNLDLTVSILTMGYWPTYPVME------------------------VTLPP EMVQYQDIFNKFYLG-------------------------------------KHSGRKLQ W-QPTLGHCVLKAWFNQG--------------------------------------NKEL QVSLFQALVLILFNEADN-----MSFEEVKAATNIEDGELRRTLQSLACGKAR---VLQK NPKG-------------RDVADNDRFVFNAEFT-------NKLFRIKIN----QIQMKET NEEQK--ATEERVYQ--DRQYQIDAAIVRIMKMR--KTLTHNLLISELYNQL-------- --------KFPVKPADLKKRIESLIDRDYMERDWDN-ANQYNYVA >Tribolium_castaneum_XM_001814147.1| . ELIAKFVDSKLRAG----NKEATEE-ELERLLDKIMVLFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--QECGG--GFTSKLEGMFK-DM ELSKDINVAFKQHL---------------------------------------------- --NISTLDLIPLDMTVNILTMGYWPTYTPMD------------------------VTLPP QMVKFQDIFKEFYLS-------------------------------------KHNGRKLQ W-QPTLGHCVLKARFKAG--------------------------------------QKEL VVSLFQTLVILLFNESDE-----HSFEYIKAATNIEDGELRRTLQSLACGKAR---VLNK IPKG-------------REIEDNDKFKFNNDFV-------NKLFRIKIN----QIQMKET TEEQK--ATEERVFQ--DRQYQIDAAIVRIMKMR--KTLSHNLLISELLAQL-------- --------KFPVKPSDLKKRIESLIDRDYMERDKDN-SNQYNYVA >Anopheles_gambiae_XM_308149.4| . ELIAKYVDMKLRAG----NKEATEE-ELEQILDKIMVQFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--QECGG--GFTSKLEGMFK-DM ELSRDINFAFKQSM---------------------------------------------- -QNSEHKELQNIDLTVNILTMGFWPTYPVME------------------------VTLPQ ELLQYQSIFNKFYLA-------------------------------------KHSGRKLQ W-QPTLGHCVLKAQFDAG--------------------------------------PKDL QVSLFQALVLLLFNYNAA-----ITFEEIRAAVNIENGELKRTLQSLACGKAR---VLTK IPKG-------------REVENTDKFQFNNEFT-------NKLFRIKIN----QIQMKET TEEQK--ATEERVYQ--DRQYQIDAAIVRIMKMR--KTLSHNLLITELYKQL-------- --------TFPVKPADLKKRIESLIDRDYMERDKDN-QNQYNYVA >Aedes_aegypti_XM_001656813.1| . ELIAKYVDMKLRAG----NKEATEE-ELEQILDKIMVQFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--QECGG--GFTSKLEGMFK-DM ELSRDINIAFKQHM---------------------------------------------- -GNSENKDLQSIDLTVNILTMGFWPTYPVVE------------------------VTLPP ELLQYQSVFNKFYLA-------------------------------------KHSGRKLQ W-QPTLGHCVLKARFDAG--------------------------------------PKDL QVSLFQSLVLLLFNYNPT-----ISFEDIKAQINIEDGEMRRTLQSLACGKAR---VLTK IPKG-------------REVEDNDKFQFNNEFT-------NKLFRIKIN----QIQMKET TEEQK--ATEERVYQ--DRQYQIDAAIVRIMKMR--KTLSHNLLISELYKQL-------- --------TFPVKPADLKKRIESLIDRDYMERDKDN-QNQYNYVA >Culex_quinquefasciatus_XM_001870775.1| . ELIAKYVDMKLRAG----NKEATEE-ELEQILDKIMVQFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--QECGG--GFTSKLEGMFK-DM ELSRDINIAFRQYM---------------------------------------------- -ANSEGKELQNIDLTVNILTMGFWPTYPVME------------------------VTLPQ ELLQYQSIFNKFYLA-------------------------------------KHSGRKLQ W-QPTLGHCVLKARFDAG--------------------------------------PKDL QVSLFQALVLLLFNYSPT-----ITFEEIKAAINIEDGELRRTLQSLACGKAR---VVSK IPKG-------------REVEDNDKFQFNNEFT-------NKLFRIKIN----QIQMKET TEEQK--ATEERVYQ--DRQYQIDAAIVRIMKMR--KTLSHNLLISELYKQL-------- --------TFPVKPADLKKRIESLIDRDYMERDKDN-QNQYNYVA >Acyrthosiphon_pisum_XM_001950884.1| . ELIAKFVDSKLKVG----NKESTEE-ELEKLLDKIMVLFRFIHGKDVFEA-FYKKDLAK- RLLLGKS----------------ASVDAEKSMLSKLK--QECGG--GFTSKLEGMFK-DM EISKDINVAYKQYL---------------------------------------------- -AHVKDIQLSVIDMTVNILTMGHWPTYVVTE------------------------VAMPN EIIEYQDCFNKFYLA-------------------------------------KHNGRKLQ W-QPTLGHCVLRSQFKQG--------------------------------------NKEL QVSLFQAMVLLLFNEYQT-----LPFKEIKTATNMEDTELRRTLQSLACGKAR---VLIK VPKG-------------REIGDIDQFSINNDFC-------NKLYRIKIN----QVQMKET NEEQK--ATEERVYQ--DRQYQMDAAIVRIMKMR--KSLMHNLLISELFNQL-------- --------KFPAKPADLKKRIESLIDRDYMERDKDN-PNQYNYIA >Felis_catus_NM_001040124.1| . ELLAKYVDSKLRTA----NKEATDE-ELEDLLAKVVILFRFIRERDVFEA-FYKKDLAK- RLLLDKS----------------ASVDAEKSMLCKLK--QECGT--AFTNKLQGMVK-DM ELSKDIMIQYMKNQ---------------------------------------------- ------NIPGNIDLTVNILTMSFWPAYISKE------------------------IHLPP DMERLQKNFKNFYLS-------------------------------------KHSGRKLQ W-QSTLGRCVLRAEFKKG--------------------------------------KKEL QVTLFQTLVLLMFNEGNR-----FSLEEIKVATGVEDRELRRTLQSLACGRAR---VLIK SPKG-------------RDVEDGDVFFCNEEFR-------HKLFKIKIN----QIQMKET IEERT--ITTQRVFQ--DRRYQIDAAIVRIMKMR--KTLSHSVLLSELYNQL-------- --------KFTLQPSDLKTRVESLIDRDYMERDKEN-PNEYKYIA >Strongylocentrotus_purpuratus_XR_025998.1| . ELVAKYVDNKLRAG----NKEATEE-ELERLLDKIMVLFRFIHGDDTIFCIFFKQRLEQ- RLGIPPD-----------SARFTNVHARAASLAKILR-KRACMI--SFKSKIEGSNM-YM KKSTDFLFSKAYHV---------------------------------------------- ----GRYIYAVGTATANTVVKSFFFTFRVLA------------------------VSLPL QMVNLQEQFKRFYLD-------------------------------------KHSGRKLQ W-QPSLGHCLVKGQFREE--------------------------------------VREL QVSLYQTLVLLLFNEGDN-----YSLEEIAQATNIEDSELRRTLQSLACGKAR---VIVK LPKG-------------REIEDGDKFLFANEFK-------HKLFRIKIN----QVQMKET VEEQV--TTQERVFQ--DRQYQIDAAIVRIMKMR--KSLSHNLLVSELYNQL-------- --------RFPVKPSDLKKRIESLIDRDYMERDKDN-PNQYHYVA >Branchiostoma_floridae_XM_002208325.1| . ELIAKYVDSKLRAG----NKEATEE-ELERMLDKIMVLFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--QECGG--AFTSKLEGMFK-DM ELSRDIMVHFKQHI---------------------------------------------- ---QHQKDSISIDLTVNILTMGYWPTYIPME------------------------VHLPP EMVRYQEIFKSFYLA-------------------------------------KHSGRKLQ W-QPTLGHCVLRADFRAG--------------------------------------KKEL QVSLFQSLVLIMFNDGDD-----FTTEYIKQYTGIEDGELRRTLQSLACGKAR---VIIK TPKG-------------KDVEDGDQFTFNNDFK-------HKLYRIKIN----QIQMKET QEENV--NTTERVFQ--DRQYQIDAAIVRIMKTR--KTLTHTLLVSELYNQL-------- --------KFPVKPADLKKRIESLIDRDYMERDKEN-SNQYHYVA >Nematostella_vectensis_XM_001627710.1| . ELIAKFVDSKLRAG----NKEATEE-ELERLLDRIMVIFRFIHGKDVYEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--QECGA--AFTSKLEGMFK-DM ELSKDVMVQFRQYL---------------------------------------------- ---QHQSLPWNMDMVVSILTMGYWPTYLPMD------------------------VHLPT EMVHYQETFKKFYLA-------------------------------------KHSGRKLQ W-QNTLGHCVVKADFSEV--------------------------------------KKEL QVSLFQTLVLLMFNEGNE-----YSLEDIKQATGVEDGELRRTLQSLACGKAR---VIKK RPQS-------------KDIEDGDIFTFNKEFK-------HKLIRIKIN----QVQMKET PEENV--NTTERVFQ--DRQYQIDAAIVRIMKTR--KTLSHTLLVSELYTQL-------- --------KFPVKPTDLKKRIESLIERDYMERDKEI-ANQYHYVA >Ornithorhynchus_anatinus_XM_001510135.1| . ELIAKYVDSKLRAG----NKEATDE-ELEKMLDKIMIIFRFIYGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMIQFKQYM---------------------------------------------- ---QNQNVPGNIELTVNILTMGYWPTYVPME------------------------VHLPP EMVKLQEIFKTFYLG-------------------------------------KHSGRKLQ W-QSTLGHCVLKAEFKEG--------------------------------------KKEL QVSLFQTLVLLMFNEGEE-----FSLEEIKQATGIEDGELRRTLQSLACGKAR---VLTK NPKG-------------KDVEDGDKFTCNDDFR-------HKLFRIKIN----QIQMKET VEEQA--STTERVFQ--DRQYQIDAAIVRIMKMR--KTLSHNLLVSEVYNQL-------- --------KFPVKPADLKKRIESLIDRDYMERDKEN-PNQYNYIA >Felis_catus_NM_001048152.1| . ELIAKYVDSKLRAG----NKEATDE-ELEKMLDKIMIIFRFIYGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMIQFKQVK---------------------------------------------- -YMQNQNVPGNIELTVNILTMGYWPTYVPME------------------------VHLPP EMVKLQEIFKTFYLG-------------------------------------KHSGRKLQ W-QSTLGHCVLKAEFKEG--------------------------------------KKEL QVSLFQTLVLLMFNEGEE-----FSLEEIKQATGIEDGELRRTLQSLACGKAR---VLAK NPKG-------------KDIEDGDKFICNDDFK-------HKLFRIKIN----QIQMKET VEEQA--STTERVFQ--DRQYQIDAAIVRIMKMR--KTLSHNLLVSEVYNQL-------- --------KFPVKPADLKKRIESLIDRDYMERDKEN-PNQYNYIA >Monodelphis_domestica_XM_001372861.1| . ELIAKYVDSKLRAG----NKEATDE-ELEKMLDKIMIIFRFIYGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMVQFKQYI---------------------------------------------- ---QNQNFPGSIELTVNILTMGYWPTYVPME------------------------VHLPA EMVRLQEIFKTFYLG-------------------------------------KHSGRKLQ W-QSTLGHCVLKAEFKEG--------------------------------------KKEL QVSLFQTLVLLMFNENEE-----FSLEDIRHATGIEDGELRRTLQSLACGKAR---VLAK NPKG-------------KDVEDGDKFICNDDFR-------HKLFRIKIN----QIQMKET VEEQA--STTERVFQ--DRQYQIDAAIVRIMKMR--KALGHNLLVSEVYNQL-------- --------KFPVKPADLKKRIESLIDRDYMERDKEN-PNQYNYIA >Danio_rerio_XM_680523.2 . ELIAKYVDSKLRAG----NKEATDE-ELEKMLDKIMIIFRFIYGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMVQFKQHM---------------------------------------------- ---QCQNIPGNIELTVNILTMGYWPTYVPME------------------------VHLPA EMVRLQEIFKTFYLG-------------------------------------KHSGRKLQ W-QSTLGHCVLKAEFKEG--------------------------------------KKEL QVSLFQTLVLLMFNEGEE-----FSLEDIKLATGIEDSELRRTLQSLACGKAR---VLTK IPKS-------------KDVEDGDKFSCNDDFK-------HKLFRIKIN----QIQMKET VEEQA--STTERVFQ--DRQYQIDAAIVRIMKMR--KTLSHNLLVSEVYNQL-------- --------KFPVKPADLKKRIESLIDRDYMERDKEN-PNQYNYVA >Tetraodon_nigroviridis_CAAE01014998.1 . ELIAKHVDSKLRAG----NKEATDE-ELEKMLDKIMIIFRFIYGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMVQFKQYM---------------------------------------------- ---QCQNIPGNIELTVNILTMGYWPTYVPME------------------------VHLPP EMVRLQEIFKTFYLG-------------------------------------KHSGRKLQ W-QSTLGHCVLKAEFKEG--------------------------------------KKEL QVSLFQTLVLLMFNEGEE-----FTLEEIKLATGIEDSELRRTLQSLACGKAR---VLTK LPKS-------------KDVEDGDKFSCNDDFK-------HKLFRIKIN----QIQMKET VEEQA--STTERVFQ--DRQYQIDAAIVRIMKMR--KTLSHNLLMSEVYNQL-------- --------KFPVKPADLKKRIESLIDRDYMERDKEN-SNQYNYVA >Xenopus_laevis_NM_001096619.1| . ELIAKHVDSKLRTG----NKEATDE-ELEKMLDKIMIIFRFIYGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMVHFKQYM---------------------------------------------- ---QNQNVPGNIELTVNILTMGYWPTYVPME------------------------VLLPP EMVKLQEIFKTFYLG-------------------------------------KHSGRKLQ W-QSTLGQCVLKAEFNEG--------------------------------------RKEL QVSLFQTLVLLMFNEGDE-----FSLEEIRQATGIEDSELRRTLQSLACGRAR---VLVK NPKS-------------KDVDDGDKFTFNDDFR-------HQLFRIRIN----QIQMKET VEEQA--STTERVFQ--DRQYQIDAAIVRIMKMR--KTLTHNLLVSEVYNQL-------- --------KFPVKPADLKKRIESLIDRDYMERDKEN-PNQYNYVA >Xenopus_tropicalis_NM_001127419.1| . ELIAKYVDSKLRTG----NKEATDE-ELEKMLDKIMIIFRFIYGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMVHFKQYM---------------------------------------------- ---QNQNVPGNIELTVNILTMGYWPTYVPME------------------------VHLPP EMVKLQEIFKTFYLG-------------------------------------KHSGRKLQ W-QSTLGQCVLKAEFNEG--------------------------------------KKEL QVSLFQTLVLLMFNEGDE-----FSLEEIRQATGIEDSELRRTLQSLACGRAR---VLVK SPKS-------------KDVDDGDKFTFNDDFR-------HQLFRIRIN----QIQMKET VEEQA--STTERVFQ--DRQYQIDAAIVRIMKMR--KTLSHNLLVSEVYNQL-------- --------KFPVKPADLKKRIESLIDRDYMERDKEN-PNQYNYVA >Otolemur_garnettii_AAQR01582435.1| . -------------------KGTTDE-ELEKMLDKIMIIFRFIHGKDVFEA-FYKKALAK- CLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMIQFKQYM---------------------------------------------- ---QSQDVPGNIELTVNILTMGYWPTYVPME------------------------VHLPP EMVKLQEIFKTFYLG-------------------------------------KHSGRKLQ W-QSTLGHCVLKAEFKEG--------------------------------------KKEL QVSLFQTRVLLMFNEGEE-----FSLEEIKQTTGIEDGELRRTLQSLACGKAR---VLEK NPKG-------------KDIEDGDKFICNDDFK-------HRLFRVKIN----QIQMKET IEEQA--STTERVFQ--DRQYQIDAAIVRIMKMR--KTLSYNLLVSEVYEQL-------- --------KFPVKPADVKKRIESLIDQDYMEREKEN-PNQYNYIA >Macropus_eugenii_ABQO010245849.1| . ELLAKYVDSKLRAG----NREATDE-ELEKILDKIMIIFRFIYGKDVFEA-FYKKDLVK- RLLFGKS----------------ASADAEKSMLSKLK--HECGA--VFTSKLEGMFK-DI ELSKDIMVQFKQYV---------------------------------------------- ---QNQNFPVSIELTVNVLTMGHWPTYMPME------------------------VHLPA ELVRLQEIFKAFYLG-------------------------------------KHSGRKLQ W-QSTLGHCVLKAEFKEG--------------------------------------KKEL QVSLFQMLVLLMFNDGEE-----FSIEDIRQATGIEDGELRRTLQSLACGKVR---VLTK YPKG-------------KDVEDGDKFTCNDDFR-------HKLFRIKIN----QIQMKET VEEQA--STTERVFQ--DRQHQIDAAIVRIMKIR--KALDHNLLVSEAYNQL-------- --------RFPVKPADLKKRIESLIDRDYMERDKEN-PTQYNYIA >Monodelphis_domestica_AAFR03062909.1| . ELLAKYVDSKLRAG----NRETTDE-ELEKMLDKIMIIFRFIYGKDVFEA-FYKKDLVK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--EFTRNLEGMFK-DM EVSKDIMVQFKQYT---------------------------------------------- ---QNQNFPGSIELTVNTLTMGYWPTYVPME------------------------VHLPA EMVRLQEVFVTFYLS-------------------------------------KHSGRKLQ W-QSSLGHCVLKAEFKEE--------------------------------------KKEL QVSLFQTLVLLMFNEGEE-----FSLEDIRQATGIEDGELRRTLQSLACGKAR---VLIK DSKG-------------KDVEDGDKFTCNDDFR-------HKLFRIKIN----QIQMKET VEEQI--STTEKVFQ--DRQYQIDAAIVRIMKIR--KALDHNLLVSEVYNQL-------- --------KFPVKPTDLKKRIESLIDMDYIERDKEN-PNRYNYIA >Xenopus_tropicalis_CR761985.2| . ELIAKYVDSKLRSG----NKEATDE-ELERLLDKIMIIFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDSEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDVMVQFKQHM---------------------------------------------- ---QNHSDPGNIDLTVNILTMGYWPTYTPVD------------------------VHLPA EMVKLQEIFKAFYLG-------------------------------------KHSGRRLQ W-QSTLGHAVLKADFKEE--------------------------------------KKEL QVSLFQTLVLLLFNKGDE-----FGFEEIKITTGIEDNELRRTLQSLACGKAR---VLNK SPKS-------------KDVEDGDRFCFNADFK-------HKLYRIKIN----QIQMKET VEEQV--NTTERVFQ--DRQYQIDAAIVRIMKMR--KTLTHNLLVSELYNQL-------- --------KFPVKPGDLKKRIESLIDRDYMERDKDN-AKQYHYLA >Tetraodon_nigroviridis_CAAE01014581.1 . ELIAKYVDSKLRAG----NKEATEE-ELERILDKIMIIFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMIQFKQYM---------------------------------------------- ---QNQSEPSNIELTVNILTMGYWPSYTPME------------------------VHLPT EMVKLQEVFKMFYLG-------------------------------------KHSGRKLQ W-QSTLGHAVLKAEFKEG--------------------------------------KKEL QVSLFQTLVLLMFNEGEE-----FSVEEIGTATGIENGELRRTLQSLACGKAR---VLNK NPRG-------------KDVEDGDRFNFNNEFK-------HKLFRIKIN----QIQMKET VEEQV--STTERVFQ--DRQYQIDAAVVRIMKMR--KTLSHNLLVSELYNQL-------- --------KFPVKPGDLKKRIESLIDRDYMERDKET-PNQYHYVA >Gasterosteus_aculeatus_DW620218.1| . ---------KLRAG----NKEATEE-ELERILDKIMIIFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMIQFKQYI---------------------------------------------- ---QNQSGPSNIELTVNILTMGYWPSYIPME------------------------VHLPP EMVKLQEVFKLFYLG-------------------------------------KHSGRKLQ W-QPTLGHAVLKAEFKEG--------------------------------------KKEL QVSLFQTLVLLMFNEGEE-----FSMDDIRAATGIEEEELRRTLQSLACGKAR---VLNK NPRG-------------KDVEDGDRFNFNNDFK-------HKLFRIKIN----QIQMKDT VEEQV--STTERVFX--DRQYQIDAAVVRIXEMX--KTLSHYLLVSELYYQL-------- --------XFPV-PGDLKKRIESLIDRDYMVRXQET-P-QYHY-- >Danio_rerio_BC054607.1 . ELIAKYVDSKLRAG----NKEATEE-ELERILDKIMIIFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMIQFKQYM---------------------------------------------- ---QNQTEPSNIELTVNILTMGYWPSYTPMD------------------------VHLPA EMVKLQEVFKLFYLG-------------------------------------KHSGRKLQ W-QPTLGHAVLKTEFKEG--------------------------------------KKEL QVSLFQTLVLLMFNESDE-----CSVEEIRVATGIEEGELKRTLQSLACGKAR---VLNK TPRG-------------KEVE-DDRFHFNSDFR-------HKLFRIKIN----QIQMKET VEEQV--STTERVFQ--DRQYQIDAAVVRIMKMR--KTLSHNLLVSELYNQL-------- --------KFPVKPADLKKRIESLIDRDYMERDKEN-SNQYHYVA >Monodelphis_domestica_XM_001364831.1| . ELIAKHVDSKLRAG----NKEATDE-ELERILDKIMIIFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMIQFKQYM---------------------------------------------- ---QNQSDPGNIDLTVNILTMGYWPTYTPME------------------------VHLTP EMVKLQEVFKTFYLG-------------------------------------KHSGRKLQ W-QTTLGHAVLKAEFKEG--------------------------------------KKEF QVSLFQTLVLLMFNEGDE-----FSFEEIKMATGVEDSELRRTLQSLACGKAR---VLIK SPKG-------------KDVDDGDKFIFNGDFK-------HKLFRIKIN----QIQMKET VEEQV--STTERVFQ--DRQYQIDAAIVRIMKMR--KTLGHNLLVSELYNQL-------- --------KFPVKPGDLKKRIESLIDRDYMERDKDN-PNQYHYVA >Gallus_gallus_XM_416943.1 . ELIAKYVDSKLRAG----NKEATDE-ELERILDKIMIIFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDVMVQFKQYM---------------------------------------------- ---QNQSDPGNIDLTVNILTMGYWPTYTPME------------------------VHLNS EMIKLQEVFKTFYLG-------------------------------------KHSGRKLQ W-QTTLGHAVLKAEFKEG--------------------------------------KKEF QVSLFQTLVLLMFNEGDE-----FSFEEIKMATGIEDSELRRTLQSLACGKAR---VLIK NPKG-------------KDVEDGDKFIFNGDFK-------HKLFRIKIN----QIQMKET VEEQV--STTERVFQ--DRQYQIDAAIVRIMKMR--KTLGHNLLVSELYNQL-------- --------KFPVKPGDLKKRIESLIDRDYMERDKDN-PNQYHYVA >Ornithorhynchus_anatinus_XM_001514976.1| . ELIAKHVDSKLRAG----NKEATDE-ELERILDKIMIIFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMVQFKQYV---------------------------------------------- ---QNQSDPGSIDLTVNILTMGYWPSYTPVE------------------------VHLPS EMVKLQEVFKTFYLG-------------------------------------KHSGRKLQ W-QTTLGHAVLKAEFKEG--------------------------------------KKEF QVSLFQTLVLLMFNEGDE-----FSFEEIKMATGVEDNELRRTLQSLACGKAR---VLNK NPKS-------------KDIDDGDKFIFNGEFK-------HKLFRIKIN----QIQMKET VEEQV--STTERVFQ--DRQYQIDAAIVRIMKMR--KTLGHNLLVSELYNQL-------- --------KFPVKPGDLKKRIESLIDRDYMERDKDN-PNQYHYVA >Mus_musculus_NM_146207.2 . ELIAKHVDSKLRAG----NKEATDE-ELERILDKIMILFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMVHFKQHM---------------------------------------------- ---QNQSAPGPIDLTVNILTMGYWPTYTPME------------------------VHLPP EMVRLQEVFKTFYLG-------------------------------------KHSGRKLQ W-QTTLGHAVLKADFKEG--------------------------------------KKEF QVSLFQTLVLLMFNEGDG-----FSFEEIKMATGIEDSELRRTLQSLACGKAR---VLIK SPKG-------------KEVEDGDKFIFNADFK-------HKLFRIKIN----QIQMKET VEEQV--STTERVFQ--DRQYQIDAAIVRIMKMR--KTLGHNLLVSELYNQL-------- --------KFPVKPGDLKKRIESLIDRDYMERDKDS-PNQYHYVA >Homo_sapiens_AF077188.1_CUL4A . ELIAKHVDSKLRAG----NKEATDE-ELERTLDKIMILFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMVHFKQHM---------------------------------------------- ---QNQSDSGPIDLTVNILTMGYWPTYTPME------------------------VHLTP EMIKLQEVFKAFYLG-------------------------------------KHSGRKLQ W-QTTLGHAVLKAEFKEG--------------------------------------KKEF QVSLFQTLVLLMFNEGDG-----FSFEEIKMATGIEDSELRRTLQSLACGKAR---VLIK SPKG-------------KEVEDGDKFIFNGEFK-------HKLFRIKIN----QIQMKET VEEQV--STTERVFQ--DRQYQIDAAIVRIMKMR--KTLGHNLLVSELYNQL-------- --------KFPVKPGDLKKRIESLIDRDYMERDKDN-PNQYHYVA >Bos_taurus_AC150564.4 . ELIAKHVDSKLRAG----NKEATDE-ELERMLDKVMILFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMVHFKQYM---------------------------------------------- ---QNQSDPGSIDLTVNILTMGYWPTYTPME------------------------VHLTP EMIKLQEVFKTFYLG-------------------------------------KHSGRKLQ W-QTTLGHAVLKAEFKEG--------------------------------------KKEF QVSLFQTLVLLMFNEGDG-----FSFEDIRMATGIEDSELRRTLQSLACGKAR---VLLK SPKG-------------KEVEDGDKFLFNAEFK-------HKLFRIKIN----QIQMKET VEEQV--STTERVFQ--DRQYQIDAAIVRIMKMR--KTLGHNLLVSELYNQL-------- --------KFPVKPGDLKKRIESLIDRDYMERDKDS-PNQYHYVA >Canis_familiaris_XM_534193.2 . ELIAKHVDSKLRAG----NKEATDE-ELERILDKVMIIFRFIHGKDVFEA-FYKKDLAK- RLLVGKS----------------ASVDAEKSMLSKLK--HECGA--AFTSKLEGMFK-DM ELSKDIMVQFKQYM---------------------------------------------- ---QNQSDPGSIDLTVNILTMGYWPTYTPME------------------------VHLTP EMIKLQEVFKTFYLG-------------------------------------KHSGRKLQ W-QTTLGHAVLKAEFKEG--------------------------------------KKEF QVSLFQTLVLLMFNEGDG-----FSFEEIKMATGIEDSELRRTLQSLACGKAR---VLVK SPKG-------------KEVEDGDTFMFNGEFK-------HKLFRIKIN----QIQMKET VEEQV--STTERVFQ--DRQYQIDAAIVRIMKMR--KTLGHNLLVSELYNQL-------- --------KFPVKPGDLKKRIESLIDRDYMERDKDN-PNQYHYVA >Drosophila_melanogaster_NM_140363.2 . -LLVTYANELMTKR------QESEE-AIIDELKRIVKCVEFLSDEYKFID-MYLKALRI- RQINETS----------------TSDGVESIMYSLLN--KKMAN--FVTRCIYVQLR-DV DKLRTLKKEFQDHL---------------------------------------------- --------NSKGIKLGFDFRPKCFKNDGSFENFN---------------------LTLPD ELQQAWKEFRIFYEAR------------------------------------KLQSKAII QLNNELSSGEITCHLNQS--------------------------------------VYIL EVSTLQMAVLMLFNRHER-----FTEQELVTALGVELETLQEALKQIKF-------LVYI EVN------------------KVNYIEINMDFT-------NRKRRLFCN----EPLPRKM RKIEE--KSEIELKI--RRDKQVDAAIVRIMKGQ--KQLEYSELISLVYEELKD------ --------RVKPQVSFIKKRLDYLVEREYLERDNYY--NIYRYL- >Drosophila_simulans_XM_002084690.1| . -LLVTYANELMTKR------QESEE-AIIDELKQIVKCVEFLSYKDTFID-MYLKALRI- RQINETS----------------TSDGAESTMFSLLN--KRFGD--LETRCLLEQLR-DV EQSRIQKSQFEDHM---------------------------------------------- --------NSKGIKLGFDFRPKCFTNKGGFENFN---------------------LTLPD ELQQAWEEFRLFYKN-------------------------------------SHESRIVQ L-NNELSSGEITCHLNQS--------------------------------------VFIL EVSTLQMAVLMLFNRHER-----FTEQELVTALGVDLETLQGALKQIKF-------LVYS ----------------------GPFIKVNMDFT-------NRKRRLILN-----KRLLTK RRKIE--EKGDDLKL--RRDKQVDAAIVRIMKGK--KELEYSQLISHVYEELKD------ --------RVKPQVSSIKERIDDLVKREYLERCDNN---TYRYL- >Drosophila_erecta_XM_001972573.1| . -LIVMYADELMRKK------QESEK-AIIEELKRIVVLVEFLNDKDTFIR-FYWNMLRI- RQIKETS----------------ASDGNESTMISLLS--KKFGD--LLIWDLRQQLK-EL ELSRIIKSQFQDHL---------------------------------------------- --------NFKGVKLGFDFRPKCFQKKNEPNFK----------------------FTFPD ELQQASMEFSMFLKYH------------------------------------SRNERKIF EFNNNLSSGEISCHLNQS--------------------------------------IHII ELSTFQMAILLLFNRHER-----ITEQDMALALGVEVETLKGFLNQKQ--------LL-- -------------------IYNGAFVEVNMNFT-------NKKRRLDFI-----SYKTKI RKLDD--NCITELKI--RRANQTDAAIARIMKKN--RELEHSELISHVFEELKN------ --------LFTPQVGYIRERLEALL-------------------- >Drosophila_yakuba_XM_002094621.1| . --IVLYANKLMTKN------QDSEI-AFINELKRIAEIVEFLDEKDKFI--YWYCNELRI RQIKETS----------------TSDDYESTMISLLN--KRFGD--TFTEPLRNQLN-EL EKSRIYQSQFQDHL---------------------------------------------- --------KSRGIQLGFDFRPKCFVNKGGIENVK---------------------LTLPD ELQPAWGEYCLFLKHPNG----------------------------------HDGPKKIE L-NNILSSGVIYCNLNQS--------------------------------------VHIL EVSNLQMAILLLFNRHER-----ITEEEMSISLGVEMETLKAALEHLKMQK-----FL-- -------------------IYSGTLVEVNMNFT-------NRKRRCNFD-----IPMIKT RKI------ELVLDM--NRSYKVDAAIVRILKKN--KELKQSELIIAVVEELKK------ --------QFTPEIRYIKERLEALLKKAVPDIERCGPEDTYRYV- >Drosophila_pseudoobscura_XM_001353463.2| . --------------------------NEMKKIVDVVL-YLSEENRKSFTN-DYFALLKK- RFIEDTS----------------ASDKNESLLISMLA--KRLGS--DFQVKQNIEWN-ET NASKGIQAKCQEFL---------------------------------------------- --------VGIGLKVQIDFRVK-FIKVRQLEGSING-------------------IRLPV ELEHFENEFRLFWSK-------------------------------------EFNRYGLN F-HPFKSWGELTMNSSSQK-------------------------------------CYTL RVNTLQMALLLQFNHQNT-----FAVQELAENVGTSPETLIKVMRPLIDHK-----LLIA SENS-------------APLTPTSSITVCMDYN---------RKRILIN----CLKSIAP MGQKP--TTERNIH-----MQALDTAIVRIMERE--KQLELDRLIYEVTLEPK------- --------LHSRPIFKIKARIEHFLKNKYL--------------- >Aedes_aegypti_XM_001658270.1| . ELLANYCDMLLRRTP--FSKRLTTE-EIESRLKDVLLVLKYVSNKDVFMR-YHKAHLTR- RLILDSS----------------ADSEKEEDMVEWLR---EVGMPADYVNKLARMFQ-DI KVSEDLNTQFRSQT---------------------------------------------- --------TRHDAINIKILNAGAWARGSERV-----------------------SVSLPL ELEDYIPEVEEFYKK-------------------------------------KHSGRKLL W-YHHMSNGTITFANNSG--------------------------------------RFDL DVTTFQMAVLFAWNQRPNDK---VSYENLRLATELPDPELRRTLWSLVAFPKLKRQLLSY DPVVAN----------PKDFAENTLFWVNQEFALIKNGKPQRRGKVNLVG----RLQLST ERSQQ--EDNQSIVQ--LRILRTQEAIIKIMKMR--KRLSNAALQAELVDILKN------ --------MFLPSKKMIKEQLEWLIEHKYMRRDDDD-INTFIYMA >Anopheles_gambiae_XM_312548.3 . ELLANYCDMLLRRTP--FSKRLTTE-EIESRLKDVLLVLKYVSNKDVFMR-YHKAHLTR- RLILDSS----------------ADSEKEEDMVEWLR---EVGMPADYVNKLARMFQ-DI KVSEDLNTQFRSQT---------------------------------------------- --------TRHDAINIKILNAGAWARGSERV-----------------------SVSLPL ELEDYIPEVEEFYKK-------------------------------------KHSGRKLQ W-YHHMSNGTITFANNTG--------------------------------------RFDL DVTTFQMAVLFAWNQRPNEK---VSYENLRLATELPDPELRRTLWSLVAFPKLKRQLLVY EPAISN----------PKDFTENTLFWVNQEFAIIKNGKPQRRGKVNLVG----RLQLST ERSQQ--EDNQSIVQ--LRILRTQEAIIKIMKMR--KRLSNAALQAELVDILKN------ --------MFLPSKKMIKEQLEWLIEHKYMRRDDDD-INTFIYMA >Tribolium_castaneum_XM_963713.2| . ELLANYCDMLLRRTP--LSKRLTSE-EIESRLKDVLLVLKYVSNKDVFMR-YHKAHLTR- RLILDAS----------------ADSEKEEDMVEWLR---EVGMPADYVNKLARMFQ-DI KVSEDLNGQFRTST---------------------------------------------- --------ARHDAINIKILNAGAWARGSERV-----------------------TVSLPV ELEDYIPEVEEFYKK-------------------------------------KHSGRKLQ W-YHHMSNGTITFATNGG--------------------------------------KFDL DVTTFQMAVLFAWNQRPHDR---ITYENLRLATELPDGELRRTLWSLVAFPKLKRQLLLF SPNVSA----------PKDFTEHTVFWVNQDFALIKNGKPQKRGKVNLIG----RLQLST ERSQM--EDNQSIVQ--LRILRTQEAIIKILKMR--KRISNASLQTELVDILKN------ --------MFLPSKKLIKEQLEWLIEHKYMRRDDDD-INTFIYMA >Drosophila_melanogaster_AY071504.1 . ELLANYCDMLLRRTP--LSKRLTSE-QIDARLRDVLLVLKYVNNKDVFMR-YHKVHLTR- RLILGTS----------------ADSEKEEDIVEWLR---EVGMPADYVNRLARMFQ-DI KVSEDLNTQFRTSI---------------------------------------------- --------SRHDAINIKILNAGAWARCSERV-----------------------SVSLPI ELEDYIPDVEEFYKK-------------------------------------KHSGRKLQ W-YHHMSNGTITFVNNFG--------------------------------------RYDL DVTTFQMAVLFAWNQRQHDK---ISYENLRLATELPDPELRRTLWSLVAFPKIKKQILLM EPAAISS---------PKDFAENTMFYINQEFAIVKNGKSQRRGKLNLIG----RLQLST ERSQQ--EDNQSIVQ--LRILRTQEAIIKIMKVR--KRMNNAALQGELIDILKN------ --------MFLPSKKMIKEQLEWLIENKYMRRDDDD-INMFIYVA >Drosophila_pseudoobscura_XM_001358625.2| . -------------------KRLTSE-QIDARLRDVLLVLKYVNNKDVFMR-YHKVHLTR- RLILGTS----------------ADSEKEEDIVEWLR---EVGMPADYVNRLARMFQ-DI KVSEDLNTQFRTSI---------------------------------------------- --------SRHDAINIKILNAGAWARCSERV-----------------------SVSLPI ELEDYIPDVEEFYKK-------------------------------------KHSGRKLQ W-YHHMSNGTITFVNNFG--------------------------------------RYDL DVTTFQMAVLFAWNQRQHDK---ISYENLRLATELPDPELRRTLWSLVAFPKIKKQILLM EPSAIGS---------PKDFTENTLFYINQEFAIVKNGKSQRRGKLNLIG----RLQLST ERSQQ--EDNQSIVQ--LRILRTQEAIIKIMKVR--KRMNNAALQGELIDILKN------ --------MFLPSKKMIKEQLEWLIEHKYMRRDDDD-INMFIYVA >Drosophila_ananassae_XM_001955329.1| . -------------------KRLTSE-QIDARLRDVLLVLKYVNNKDVFMR-YHKVHLTR- RLILGTS----------------ADSEKEEDIVEWLR---EVGMPADYVNRLARMFQ-DI KVSEDLNTQFRSST---------------------------------------------- --------SRHDAINIKILNAGAWARCSERV-----------------------SVSLPI ELEDYIPDVEEFYKK-------------------------------------KHSGRKLQ W-YHHMSNGTITFVNNFG--------------------------------------RYDL DVTTFQMAVLFAWNQRQHDK---ISYENLRLATELPDPELRRTLWSLVAFPKIKKQILLM EPTAIAS---------PKDFTENTMFYINQEFAIVKNGKSQRRGKLNLIG----RLQLST ERSQQ--EDNQSIVQ--LRILRTQEAIIKIMKVR--KRMNNAALQGELIDILKN------ --------MFLPSKKMIKEQLEWLIEHKYMRRDDDD-INMFIYVA >Acyrthosiphon_pisum_XM_001950058.1| . ELLANYCDMLLRKTP--LSKRLTAD-EIESKLKDVLLVLKYVQNKDVFMR-FHKAHLTR- RLILDTS----------------ADSEKEENMVEWLR---EVGMPADYVNKLARMFQ-DI KVSEDLNQQFKETY---------------------------------------------- ---RNLKGSIADSINIKILNAGAWSRGSERV-----------------------TVSLPM ELEDYIPEVEDFYRK-------------------------------------KHSGRKLQ W-YHHMSNGTITFLNEIG--------------------------------------RFDI DVTTFQMAVLFAWNQRPKDK---ISYENLRLATELPDPELRRTLWSLVNFPKLKKQVVLV VPEVPS----------PKEFNENTIFWINEQFSIVKNGKLQKRGKINLIG----RLQLST ERSKE--EDNECIVQ--LRILRVQEAIIKILKMR--KQISNWNLQTELVDILKN------ --------MFLPSKKMIKEQVEWLIEHKYMKRDEDD-INLFVYIA >Apis_mellifera_XM_623955.2 . ELLANYCDMLLRKTP--LSKKLTSD-EIESKLKDVLLVLKYVQNKDVFMR-YHKAHLTR- RLILDTS----------------ADSEKEENMVEWLR---EVGMPADYVNKLARMFQ-DI KVSQDLNQQFKEQC---------------------------------------------- ------RAAIADSINIKILNAGAWARGSERV-----------------------TVSLPL QLEDYIPEVEEFYKK-------------------------------------KHSGRKLQ W-YHHMSNGTITFSNQVG--------------------------------------RFDV DVTTFQMAVLFAWNQRPFEK---ISYENLRLATELPDPELRRTLWSLCAFPKLKRQLLLV EPHAHS----------PKDFANDTRFWVNQEFAIVKNGKLQKRGKINLIG----RLQLST ERSKE--EDNQSIVQ--LRILRVQEAIIKILKMR--KKISNAQLQTELVDILKN------ --------MFLPSKKMIKEQIEWLIEHKYIRRHDDD-INTFVYMA >Branchiostoma_floridae_XM_002210983.1| . ELLANYCDMLLRKTP--LSKKLTSD-EIDARLKDVLLVLKYVQNKDVFMR-YHKAHLTR- RLILDSS----------------ADSEKEENMVEWLR---EVGMPADYVNKLARMFQ-DI KVSEDLNSQFKEAIRDKG---------------HGSIADCVNIKVLNAGAWARSSERVFF TLHIFVSFASTDCVNIKVLNAGAWARSSERV-----------------------FVSLPM ELEDYIPEVEEYYRK-------------------------------------THSGRKLQ W-HHLMSNGIITFKNKVG--------------------------------------QYDL EVTTFQMAVLFSWNQRPLER---IPLENLRLATELPDTELRRTLWSLVAFPKIKRQVLVY EPEAQS----------PKDFQEGTVFWVNQEFGLIKNGKLQKRGKINLIG----RLQLST ERTRE--EDNEGIIQ--LRILRTQEAIVKIMKMR--KRISNAQLQTELVEILKN------ --------MFIPSKKMIKEQIEWLIEHKYMRRDEDN-INMFIYMA >Danio_rerio_XM_001922844.1| . ELLANYCDMLLRKTP--LSKKLTSE-EIEAKLKEVLLVLKYVQNKDVFMR-YHKAHLTR- RLILDIS----------------ADSEIEENMVEWLR---EVGMPADYVNKLARMFQ-DI KVSEDLNQSFKEMH---------------------------------------------- --KHNKLALPADSVNIKILNAGAWSRSSEKV-----------------------FVSLPT ELEDLIPEVEDFYKK-------------------------------------NHSGRKLH W-HHLMSNGIITFKNEVG--------------------------------------QYDL EVTTFQLAVLFAWNQRPRER---ISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLSY EPVVGS----------PKDFAEGTVFSINQEFSLIKNSKVQKRGKINLIG----RLQLTT ERMRE--EENEGIVQ--LRILRTQEAIIQIMKMR--KRISNAQLQTELVEILKN------ --------MFLPQKKMIKEQIEWLIEHKYIKRDETD-INTFIYMA >Xenopus_laevis_NM_001110722.1| . ELLANYCDMLLRKTP--LSKKLTSE-EIEAKLKEVLLVLKYVQNKDVFMR-YHKAHLTR- RLILDIS----------------ADSEIEENMVEWLR---EVGMPADYVNKLARMFQ-DI KVSEDLNQAFKEMH---------------------------------------------- --KNNKLALPADSANIKILNAGAWSRSSEKV-----------------------FVSLPT ELEDLIPEVEEFYKK-------------------------------------NHSGRKLH W-HHLMSNGIITFKNEVG--------------------------------------QYDL EVTTFQLAVLFAWNQRPREK---ISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLSY EPTVNS----------PKDFTEGTLFSVNQEFGLIKNGKVQKRGKINLIG----RLQLTT ERMRE--EENEGIVQ--LRILRTQEAIIQIMKMR--KKITNAQLQTELVEILKN------ --------MFLPQKKMIKEQIEWLIEHKYIRRDECD-INTFLYMA >Xenopus_tropicalis_NM_001079368.1| . ELLANYCDMLLRKTP--LSKKLTSE-EIEAKLKEVLLVLKYVQNKDVFMR-YHKAHLTR- RLILDIS----------------ADSEIEENMVEWLR---EVGMPADYVNKLARMFQ-DI KVSEDLNQAFKEMH---------------------------------------------- --KNNKLALPADSVNIKILNAGAWSRSSEKV-----------------------FVSLPT ELEDLIPEVEEFYKK-------------------------------------NHSGRKLH W-HHLMSNGIITFKNEVG--------------------------------------QYDL EVTTFQLAVLFAWNQRPREK---ISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLSY EPTVNS----------PKDFTEGTLFSVNQEFSLIKNGKVQKRGKINLIG----RLQLTT ERMRE--EENEGIVQ--LRILRTQEAIIQIMKMR--KKITNAQLQTELVEILKN------ --------MFLPQKKMIKEQIEWLIEHKYIKRDESD-INTFIYMA >Mus_musculus_NM_027807.2| . ELLANYCDMLLRKTP--LSKKLTSE-EIEAKLKEVLLVLKYVQNKDVFMR-YHKAHLTR- RLILDIS----------------ADSEIEENMVEWLR---EVGMPADYVNKLARMFQ-DI KVSEDLNQAFKEMH---------------------------------------------- --KNNKLALPADSVNIKILNAGAWSRSSEKV-----------------------FVSLPT ELEDLIPEVEEFYKK-------------------------------------NHSGRKLH W-HHLMSNGIITFKNEVG--------------------------------------QYDL EVTTFQLAVLFAWNQRPREK---ISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLY DPQVNS----------PKDFTEGTLFSVNQDFSLIKNAKVQKRGKINLIG----RLQLTT ERMRE--EENEGIVQ--LRILRTQEAIIQIMKMR--KKISNAQLQTELVEILKN------ --------MFLPQKKMIKEQMEWLIEHRYIRRDEAD-INTFIYMA >Pongo_abelii_NM_001132119.1| . ELLAIYCDMLLRKTP--LSKKLTSE-EIEAKLKEVLLVLKYVQNKDVFMR-YHKAHLTR- RLILDIS----------------ADSEIEENMVEWLR---EVGMPADYVNKLARMFQ-DI KVSEDLNQAFKEMH---------------------------------------------- --KNNKLALPADSVNIKILNAGAWSRSSEKV-----------------------FVSLPT ELEDLIPEVEEFYKK-------------------------------------NHSGRKLH W-HHLMSNGIITFKNEVG--------------------------------------QYDL EVTTFQLAVLFAWNQRPREK---ISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLY EPQVNS----------PKDFTEGTLFSVNQEFSLIKNAKVQKRGKINLIG----RLQLTT ERMRE--EENEGIVQ--LRILRTQEAIIQIMKMR--KKISNAQLQTELVEILKN------ --------MFLPQKKMIKEQIEWLIEHKYIRRDESD-INTFIYMA >Oryctolagus_cuniculus_NM_001082355.1| . ELLANYCDMLLRKTP--LSKKLTSE-EIEAKLKEVLLVLKYVQNKDVFMR-YHKAHLTR- RLILDIS----------------ADSEIEENMVEWLR---EVGMPADYVNKLARMFQ-DI KVSEDLNQAFKEMH---------------------------------------------- --KNNKLALPADSVNIKILNAGAWSRSSEKV-----------------------FVSLPT ELEDLIPEVEEFYKK-------------------------------------NHSGRKLH W-HHLMSNGIITFKNEVG--------------------------------------QYDL EVTTFQLAVLFAWNQRPREK---ISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLY EPQVNS----------PKDFTEGTLFSVNQEFSLIKNAKVQKRGKINLIG----RLQLTT ERMRE--EENEGIVQ--LRILRTRKLYIQIMKMR--KKISNAQLQTELVEILKN------ --------MFLPQKKMIKEQIEWLIEHKYIRRDESD-INTFIYMA >Strongylocentrotus_purpuratus_XM_001177403.1| . ELLANYCDMLLRKTP--LSKRLTSE-EIESKLRNVLLVLKYVQNKDVFMR-YHKAHLTR- RLILDTS----------------ADSEKEENMVEWLR---EVGMPADYVNKLARMFQ-DI KVSEDLNQSFKELH---------------------------------------------- -------RNNYDNMNIKILNAGAWSRSSERV-----------------------PCSLPV ELEDFIPEVEEFYRN-------------------------------------KHNGRKLQ W-HHHVHTATITMKNEVG--------------------------------------MFDL EVTTFQMAVLYAWNQRPLDK---ISLENLRLATELPDHELRRTLWSLVAFAKLKRQMVLM QPEAKS----------PKEFVDGTVFWVNQDFAVIKNGKPQKRGKINLIG----RLQLST ERSTE--EDKEGIVQ--LRILRTQEAIVKIMKMR--KKLNNAQLQTELVEILKN------ --------MFLPQKKMIKEQIEWLIEHKYMKRDEGD-INTFIYLA >Nematostella_vectensis_XM_001630774.1| . ELLANYCDMLLRKTT--YSKKLTSD-EIESKLKDVLLVLKYVVNKDVFMR-YHKAHLTR- RLILDTS----------------ADSEMEENMVEWLR---DVGMPADYINKLARMFQ-DI KVSEDLNQEFKRTC---------------------------------------------- ----RDKGDIADSINIKILNAGAWSRASERI-----------------------PVSLPT ELEDCIPEVEEFYRK-------------------------------------NHSGRKLQ W-HHLMSNGVITFSNKTG--------------------------------------KFDL EVTTFQMSVLFAWNERPLDH---ISYENLRLATELPDSELRKTLWSMVSIPKLKRQILTC EPAVRS----------PKDFTDSSMFWVNQDFALIKNGKVQKRGKVNLIG----RLQLST DKAKQ--EENEGIVA--LRILRIQEAIVKIMKMR--KRITNAALQTELVEILKN------ --------MFIPQKKMIKEQTEWLIEHKYLKRDEED-INTFIYLV >Ciona_intestinalis_XR_053037.1| . ELLANFCDMLLRKTP--LSKKLSSE-EVDAKLKDVLLVLKYVSNKDVFMR-YHKAHLTR- RLILGTS----------------ADSEKEENMVEGLR---EVGMPADFVNKLARMFQ-DI KVSEDLNTQFKEAR---------------------------------------------- ------EDRSSELANIKILNAGAWSRRSDRI-----------------------PVSLPA ILEDLIPDVEEFYKS-------------------------------------KHHGRMLN W-NHLMSNGVMTFKTEVG--------------------------------------SYDI EVTTFQMSVLHIWNSRPTES---ISFESLRLATQLPDTELRKTLWSLVANPKLKRQVLLC EPKLSS----------PKEFQESSMLAVNHQFAVMKAGKPQKRGRVNLIG----RLQLST DKSRE--EDNEGITQ--LRILRTQEAIVKILKMR--KRINNAQLQTELVEILKN------ --------LFLPQKKLIKQQIEWLIENKYMKRDDDD-INTFIYI- >Brugia_malayi_XM_001901874.1| . ELLANFTDLILRKTS--LSKRLSSE-EIDAKLNDVLLILKYVQNKDVFMR-FYKTHLTR- RLILELS----------------ADQEKEEQMITRMR---EVGMPADFVTKLFRMLQ-DI EVNKDLNSIFKSSI-----------------------------------------ASNNN CIAEAFKFVNVDSISIKILNAGAWSRGAADR----------------------TQVQMPR ELEDFIPEVEDFYRK-------------------------------------QHSGRKLQ W-HHHWSHGTVIFTNKMG--------------------------------------KFDL DVTTLQLSVLYCWNDRPHEQ---LSFECLRTATQLSAPELMRTLYSLVAFPKMRHQVLCT NCSTLN----------SRDFNDSTLFWINQQFTVIKNGREQNRGRINLIG----RLQLSM KTNVQ--EEHDDIIA--LRILRVQEAIVKVMKVR--KRCQSAQLQTELIQLLKH------ --------MFLPPKKMIKEQIEWLIENGFIARDSND-LNVFLYV- >Caenorhabditis_elegans_cul5_NM_073215.3| . ELLANYCDLLLRKTQ--LSKKLTSE-EIDEKLNQVLLVLKYVENKDVFMR-FHRAHLSR- RLILEMS----------------ADQEKEEMMVTKLR---ECGMPSDAVNKLSRMLQ-DI ELNKDMNSSFKKAL---------------------------------------------- -TGTNNNKSIADSINMKVLNGGAWGRGGSER----------------------IRFSLPR ELEDFVPEMEAFYKK-------------------------------------QHNGRKLC W-MHHWSSGTMVFGTANG-------------------------------------GRFDL ECTTFQMAVLFCFNDRAHDK---ISLETLRLATELPDAELNRTLLSLVAYPKMRYQILLC DVPSTTVT--------ARDFTDSTKFLINHDFNVVKNGKSQQRGKVNLIG----RLQLSL EANAE--KEHESIVA--LRELRVQEGIVKILKTR--KTYTLAQLTMELVEILKP------ --------LFIPNRKIIKEQIDWLIENKYMERRADD-INTFVYIS >Caenorhabditis_briggsae_XM_001674006.1| . ELLANYCDLLLRKTQ--LSKKLTSE-EIDEKLGQVLLVLKYVENKDVFMR-FHRAHLSR- RLILEMS----------------ADQEKEEMMVTKLR---ECGMPSDAVNKLSRMLQ-DI ELNKDMNTLFKKVL---------------------------------------------- -TGTNNNKSIADSINLKVLNGGAWGRGGSER----------------------IRFSLPR ELEDFVPEMEAFYKK-------------------------------------HHNGRKLN W-MHHWSSGTMVFGTASG-------------------------------------GRFDL EITTFQMAVLFCFNERAHEK---ISLETLRLATELPDAELNRTLLSLVSYPKMRSQILLC DVASQNIT--------ARDFTDSTKFSINHNFHLVKNGKSQQRGKVNLIG----RLQLSL EANAE--KEHESIVA--LREYRVQEGIVKILKTR--KTITLAQMTMELVEILKP------ --------LFIPNRRIIKEQIDWLIENRFMERRPDD-INTFVYLA >Trichoplax_adhaerens_XM_002112880.1| . -------------------KKLTSG-EIERRLKDALLLLKYVQNKDVFMR-YYKVHLMK- RLLLDIT----------------ADQEMEENMIEWLR-NIEMPV--EFINKLAKMFH-DI HISHDVNNLFKEAR---------------------------------------------- ------SKEASDTINAKILSAAAWSRGSENT-----------------------NVSLPS ELAEYIKEIEGFYHQ-------------------------------------KYTTRKLQ W-HHLYSSGTITFATNYG--------------------------------------KYDL EVTTFQMSVLFAWNLRPSDE---ISLDSLRIATGLNESELRKTLFSLTNNSKMKYQILLV NPSVQS----------FREYTHQSIFRINRDFNIVKSGKIQKRGKVTLIG----RLQLAP EKGNE--EENKEIAS--LRMLRTQEAIIKIMKMR--KRLRFGQLQTELVNVLKN------ --------MFFPQKAVVKDQLEKLIEENYIKRDEQD-LNTFIYLA >Drosophila_pseudoobscura_XM_001357383.2| . EYVARYCDTLLKKS-----K-TCEA-EIDQKLTNNITIFKYIEDKDVYQK-FYSRLLAK- RLIHEQS----------------QSMDAEEGMINRLK--QACGY--EFTNKLHRMFT-DI SVSTDLNNKFNTHL---------------------------------------------- ---KDTNVELGINLSIKVLQAGAWPLGSTQV----------------------IPFAVPQ EFEKSIKMFEDYYHK-------------------------------------LFSGRKLT W-LHHMCHGELKLSHLKK--------------------------------------SYIV TMQTYQMAIILLFETCDS-----LSCREIQNTLQLNDETFQKHMQPMIESK-----LLNA SSEN---------------LAGETRIDLNMDYT-------NKRTKFKIS----SALQKET PQEVE--HTINSVDE--DRKLFLQAAIVRIMKAR--KVLKHNALIQEVLSLSKV------ --------SFTPNIAMIKKCVESLIDKQYIERTANS-GDEYSYMA >Drosophila_melanogaster_NM_165390.1_Cul-2 . EYVAKYCDTLLKKS-----K-TCEA-EIDQKLTNNITIFKYIEDKDVYQK-FYSRLLAK- RLIHEQS----------------QSMDAEEGMINRLK--QACGY--EFTNKLHRMFT-DI SVSVDLNNKFNTHL---------------------------------------------- ---KDSNVDLGINLAIKVLQAGAWPLGSTQV----------------------IPFAVPQ EFEKSIKMFEDYYHK-------------------------------------LFSGRKLT W-LHHMCHGELKLSHLKK--------------------------------------SYIV TMQTYQMAIILLFETCDS-----LSCREIQNTLQLNDETFQKHMQPIIESK-----LLNA SSEN---------------LAGETRIELNLDYT-------NKRTKFKIS----SALQKET PQEVE--HTINSVDE--DRKLFLQAAIVRIMKAR--KVLKHNALIQEVLSLSKV------ --------SFTPNIAMIKKCVESLIDKQYIERTANS-GDEYSYMA >Drosophila_grimshawi_XM_001988000.1| . EYVAKYCDTLLKKS-----K-TCEA-EIDQKLTNNITIFKYIEDKDVYQK-FYSRLLAK- RLIHEQS----------------QSMDAEEGMINRLK--QACGY--EFTNKLHRMFT-DI SVSTDLNNKFNNHL---------------------------------------------- ---KDNDIDLGINLSIKVLQAGAWPLGSTQV----------------------IPFAVPQ EFEKSIKMFEDYYHN-------------------------------------LFSGRKLT W-LHHMCHGELKLSHLKK--------------------------------------SYIV TMQTYQMAIILLFETCDT-----LSCREIQNTLQLNDETYQKHMQPMIESK-----LLNA SSEN---------------LSGDTRIELNMDYT-------NKRTKFKISS----ALQKET PQEVE--HTINSVDE--DRKLFLQAAIVRIMKAR--KVLKHNALIQEVLSLSKV------ --------SFTPNIAMIKKCVESLIDKQYIERTANS-GDEYSYMA >Anopheles_gambiae_XM_313365.3 . ELVAKYCDSLLKKS-----K-TTEG-EIDQKLTRSIIIFKYIEDKDVYQK-FYSRMLAK- RLIHEQS----------------QSMDAEELMINKLK--QACGY--EFTNKLHRMFT-DI SVSTDLNAKFSKYL---------------------------------------------- ---NDNKHETGINFSVKVLQAGAWPLGPTQV---------------------VASFAIPQ EFEKSIRLFEEFYHI-------------------------------------NFSGRKLT W-LHHLCHGEMKLSFEKR--------------------------------------NYIV TMQTYQMAILLMFENTDK-----YTCKELQTSLQLQQEIFQRHLQSLVEAK-----ILLL NEEK---------------MNDDTEVSINVNYS-------NKRTKFKIT----TNLQKET PQEVE--HTMNAVDE--DRKMYLQAAIVRIMKSR--KVLRHNTLIQEILSQSKV------ --------SFAPNVSMIKKCIESLIDKQYIERTPNS-GDEYSYVA >Aedes_aegypti_XM_001652290.1| . ELVAKYCDSLLKKS-----K-TTEI-EIESKLTKSITIFKYIEDKDFYQK-FYSRMLAK- RLIHDQS----------------QSMDAEEMMINKLK--QACGY--EFTNKLHRMFT-DI SVSADLNTKFAHYL---------------------------------------------- ---KQQNKELGINLSIKILQAGAWPLGPTQI---------------------TSGFAVPQ EFEKPIRLFESFYHV-------------------------------------NFSGRKLT W-LNHLCHGELKISFADR--------------------------------------NYMV TMQTYQMAILLLFESTDS-----LHYKEIQDSLQLNKDMLQKHILSLVESK-----LLLS DTEG---------------VDENSKLSLNKNYI-------NKRTKFKIT----AALQKET PQEIE--NTINSVDE--DRKMYLQATIVRIMKSR--KVLRHNALIQEILAQSKV------ --------SFAPSIGMIKKCIESLIDKQYIERTPNS-GDEYSYVA >Tribolium_castaneum_XM_969486.1| . EFLAKYCDALLRKS----SKGISDS-EVDEKLAESITIFKYIDDKDVFQK-FYSRMLAK- RLIHQQT----------------QSMDAEEAMINRLK--QACGY--EFTSKLHRMFT-DM SVSADLNNKFNAFL---------------------------------------------- ---KQDNIDLGINFSIYVLQAGAWPLGQTVT----------------------TPFTYPR QLEKSVQMFENFYHN-------------------------------------RFNGRKLT W-LHNLCQAELKLGHLKK--------------------------------------SYLV TMQTFQMATLLLFEHTDS-----LTFREIRESLQLTAEQYHRYAASLIDCK-----LLIA DSTD---------------LKPETVLRLNMEYN-------NKRTKFRIN----AAVQKES PQEIE--QTMNSVEE--DRKMYLQAAIVRIMKSR--KILKHNALIQEVYAQSKV------ --------SFAPSVQLIKKCIESLIDKQYIERTPHS-SEEYSYVA >Apis_mellifera_XM_001121309.1| . ------------KS----AKAASEG-EVEEKLAQCITVFKYVDDKDVFQK-FYARMLAK- RLIHQQS----------------QSMDAEESMIDRLK--QACGY--EFTNKLHRMFT-DM SVSADLNAKFTTSL---------------------------------------------- -REGDRENQLGIGFVVYVLQAGAWPLGLPPS---------------------SGPFDIPQ QLEKSIQAFETFYHA-------------------------------------QFNGRKLT W-LHHLCQGELKFNYLKK--------------------------------------PYLV TVQTYQMALLLLFEHCDS-----IQCREAAASLRLSHDQLVKHATSLVDCK-----ILKK STDG--------------ELEEDTILSLNFDYY-------NKRTKFRIT-GTLQRDVPHE CHDVE--TTHRSVDD--DRKLYLQAAIVRIMKSR--KVLRHNQLVQEVLSQSKV------ --------TFAPSISMIKKCIEALIDKQYIERTPNN-ADEYSYVA >Nasonia_vitripennis_XM_001599066.1| . ELLAKYCDSLLKKS----AKVASES-EIEEKLARSITVFKYVDDKDVFQK-FYARMLAK- RLIHQQS----------------QSMDAEEAMIDRLK--QACGY--EFTNKLHRMFT-DM SVSADLNTKFTASL---------------------------------------------- REREGEKHQFGIGFVVYVLQAGAWPLGLPPS---------------------PGPFHVPQ QLEKSVQAFESFYHA-------------------------------------QFSGRKLT W-LHHLCQGELKLNYLKK--------------------------------------PYLV TVQTYQMALLLLFEHCDS-----ISCKEAAVSLRLSHDQLVKHAVSLVDCK-----ILKK STEE--------------DLEEDTILTLNFEYY-------NKRTKFRIT----GALQRDA PHDTE--ATHRSVDD--DRKLYLQAAIVRIMKSR--KVLRHNQLVQEVLGQSKV------ --------TFAPSIGMIKKCIENLIDKQYIERTSNS-ADEYSYVA >Acyrthosiphon_pisum_XM_001947531.1| . EYLSKYCDKLLKKS----CKGLSEA-EIEHKLLQSITIFKYINDKDIFQN-IYQVHLAK- RLILQQS----------------QSTVGEEGMINNLK--QLCGY--EFANKLHCMFT-DI RISEGLNTQFQKEI---------------------------------------------- --LKTTKDKLTLSFSANILQTGAWPMILSTK-----------------------SFAIPE QLITCSKNFEDFYKE-------------------------------------KFVGRKLT W-LHHHSQGELKLNYLPK--------------------------------------MYIV TLHIFQMSILLLFENNDT-----LKYSEINEILQLSDDHFQKQINSLVNCK-----LLSL DGDN---------------------VKLNMNFS-------NKRTKLCIT----SAVLKDT PQEIE--QSTNSVEI--DREAFLHATIIRIMKMR--KTLRHNKLVIEIISQTKS------ ---------FLPSNGFINRSIKILIDKGYLECSPNLP-VEYNYVA >Acyrthosiphon_pisum_XM_001946570.1| . EYLSKYCDNLLKKS----SKGMCEG-EIDQKLLQSITIFKYVDDKDIFQR-FYQRHLAK- RLIHQQS----------------QSMDGEEGMINKLK--QACGY--EFTNKLHRMFT-DI RVSEGLNAKFHSEF---------------------------------------------- ---LKPTDKLNVSFSMYVLQTGAWPLGSSIV----------------------SSFVIPQ QLIPCIQYFEAFYKE-------------------------------------KFNGRKLT W-LHHHCQGELKLNYLQK--------------------------------------VYIV TMQTFQMSIMLLFEDRDT-----INYTEIHEILQLTSDQFQKHINSLIECK-----LLL- --------------------IDGDNVSLNMAYT-------NKRTKLRITS----ALQKET PQEVE--QTVNSVED--DRKTYLQAAIVRIMKSR--KILRHNQLVNEILSQSQT------ ---------FAPSIALIKKSIETLIDKGYLERTPNS-SDGYSYVA >Branchiostoma_floridae_XM_002228533.1| . EWLAKYCDMLLKRS----TKGMSES-EVDDKLSASITVFKYLDDKDVYQK-FYSKMLAK- RLIQGNS----------------VSMDAEEAMINRLK--QACGY--EFTNKLHRMYT-DI NVSAEHNKKFNEWM---------------------------------------------- ---RENKEELGIHFNIYVLQAGAWPLGLTNP----------------------SPLNIPQ ELEKSVKMFDMFYKE-------------------------------------RFNGRKLT W-LHQLCNGEVRTCFLKK--------------------------------------SYII TLSMYQMAVLLLFNGSDK-----LTMAEIQSSTQMAEGELGKNVQSLVDAK-----LLIN LDGK-------------EQLTPNVVLTVNVEYT-------NKRTKFKIP----ALYQKET VQEVE--QAHKAVDE--DRKLYLQAAIVRIMKAR--KALKHNTLIQEVISQSRA------ --------RFNPSISMIKRCIEQLINKEYIARSNDA-ADEYTYIA >Danio_rerio_BC085675.1 . ELLAKYCDNLLKKS----AKGMTEN-EVEDKLTSFITVFKYIDDKDVFQK-IYARMLAK- RLIHGLS----------------LSMDSEEAMINKLK--QACGY--EFTSKLHRMYT-DM SVSTDLNNKFNNFI---------------------------------------------- -KTQETVVDLGISFQIYVLQAGAWPLTHVPS----------------------STFAIPQ ELEKSVQMFELFYNQ-------------------------------------HFSGRKLT W-LHYLCTGEVKMNYLSK--------------------------------------PYVA VVTTYQMAVLLAFNNSET-----VSYKELQDSTQMNEKELQKTIKSLLDVK-----MISH DLQK-------------EEIEPESTFSLIMSFT-------SKRTKFKIT----TSMQKDT PQELE--QTRSAVDE--DRKMYLQAAIVRIMKAR--KVLRHNALIQEVINQSKA------ --------RFNPSISMIKKCIEVLIDKQYIERSQSS-ADEYSYVA >Xenopus_laevis_NM_001086568.1| . ELLAKYCDNMLKKS----AKGMTEN-EVEDKLTSFITVFKYIDDKDVFQK-FYARMLAK- RLIHGLS----------------MSMDSEETMINKLK--QACGY--EFTSKLHRMYT-DM SVSADLNNKFNNFI---------------------------------------------- -KSQDTVIDLGISFQIYVLQAGAWPLTQAPS----------------------STFAIPQ ELEKSVQMFELFYNQ-------------------------------------HFSGRKLT W-LHYLCTGEVKMNYLCK--------------------------------------PYVA MVTTYQMAVLLAFNNSEI-----ITYKELQDSTQMNEKELTKTIKSLLDVK-----MINH DSDK-------------EDIEGESTFSLNMNFS-------SKRTKFKIT----TPMQKDT PQEVE--QTRSAVDE--DRKMYLQAAIVRIMKAR--KVLRHNALIQEVISQSRA------ --------RFNPSISMIKKCIEVLIDKQYIERSQAS-ADEYSYVA >Monodelphis_domestica_XM_001366362.1| . ELLAKYCDNLLKKS----AKGMTEN-EVEDKLTSFITVFKYIDDKDVFQK-FYARMLAK- RLIHGLS----------------MSMDSEEAMINKLK--QACGY--EFTSKLHRMYT-DM NVSADLNNKFNNFI---------------------------------------------- -KNQDTVIDLGISFQIYVLQAGAWPLTQSPS----------------------STFAIPQ ELEKSVQMFELFYSQ-------------------------------------HFSGRKLT W-LHYLCTGEVKMNYLSK--------------------------------------PYVA MVTTYQMAVLLAFNNSET-----VSFKELHDITQMNEKELAKTIKSLLDVK-----MINH DSEK-------------EDIDAESTFSLNMNFS-------SKRTKFKIT----TSMQKDT PQEME--QTRSAVDE--DRKMYLQAAIVRIMKAR--KVLRHNALIQEVISQSRA------ --------RFNPSISMIKKCIEVLIDKQYIERSQAS-ADEYSYVA >Ornithorhynchus_anatinus_XM_001508513.1| . ELLAKYCDNLLKKS----AKGMTEN-EVEDKLTSFITVFKYIDDKDVFQK-FYARMLAK- RLIHGLS----------------MSMDSEEAMINKLK--QACGY--EFTSKLHRMYT-DM SVSADLNNKFNNFI---------------------------------------------- -KNQDTTIDLGISFQIYVLQAGAWPLTQAPS----------------------STFAIPQ ELEKSVQMFELFYSQ-------------------------------------HFSGRKLT W-LHYLCTGEVKMNYLCK--------------------------------------PYVA MVTTYQMAVLLAFNNSET-----ISYKELQDSTQMNEKELTKTIKSLLDVK-----MINH DSEK-------------EDIDAESTFSLNMNFS-------SKRTKFKIT----TSMQKDT PQEME--QTRSAVDE--DRKMYLQAAIVRIMKAR--KVLRHNALIQEVISQSRA------ --------RFNPSISMIKKCIEVLIDKQYIERSQAS-ADEYSYVA >Gallus_gallus_AJ851765.1 . ELLAKYCDNLLKKS----AKGMTEN-EVEDKLTSFITVFKYIDDKDVFQK-FYARMLAK- RLIHGLS----------------MSMDSEEAMINKLK--QACGY--EFTSKLHRMYT-DM SVSADLNNKFNNFI---------------------------------------------- -KNQDTIIDLGISFQIYVLQAGAWPLTQAPS----------------------STFAIPQ ELEKSVQMFELFYSQ-------------------------------------HFSGRKLT W-LHYLCTGEVKMNYLCK--------------------------------------PYVA MVTTYQMAVLLAFNNSET-----VSYKGLQDSTQMNEKELTKTIKSLLDVK-----MINH DSDK-------------EDVEAESTFSLNMNFS-------SKRTKFKIT----TSMQKDT PQEME--QTRSAVDE--DRKMYLQAAIVRIMKAR--KVLRHNALIQEVISQSRA------ --------RFNPSISMIKKCIEVLIDKQYIERSQAS-ADEYSYVA >Homo_sapiens_CUL2_U58088.1 . ELLAKYCDNLLKKS----AKGMTEN-EVEDRLTSFITVFKYIDDKDVFQK-FYARMLAK- RLIHGLS----------------MSMDSEEAMINKLK--QACGY--EFTSKLHRMYT-DM SVSADLNNKFNNFI---------------------------------------------- -KNQDTVIDLGISFQIYVLQAGAWPLTQAPS----------------------STFAIPQ ELEKSVQMFELFYSQ-------------------------------------HFSGRKLT W-LHYLCTGEVKMNYLGK--------------------------------------PYVA MVTTYQMAVLLAFNNSET-----VSYKELQDSTQMNEKELTKTIKSLLDVK-----MINH DSEK-------------EDIDAESSFSLNMNFS-------SKRTKFKIT----TSMQKDT PQEME--QTRSAVDE--DRKMYLHAAIVRIMKAR--KVLRHNALIQEVISQSRA------ --------RFNPSISMIKKCIEVLIDKQYIERSQAS-ADEYSYVA >Mus_musculus_AK144693.1| . ELLAKYCDNLLKKS----AKGMTEN-EVEDKLTSFITVFKYIDDKDVFQK-FYARMLAK- RLIHGLS----------------MSMDSEEAMINKLK--QACGY--EFTSKLHRMYT-DM SVSADLNNKFNNFI---------------------------------------------- -RNQDTVIDLGISFQIYVLQAGAWPLTQAPS----------------------STFAIPQ ELEKSVQMFELFYSQ-------------------------------------HFSGRKLT W-LHYLCTGEVKMNYLGK--------------------------------------PYVA MVTTYQMAVLLAFNNSET-----VSYKELQDSTQMNEKELTKTIKSLLDVK-----MINH DSEK-------------EDIDAESSFSLNMSFS-------SKRTKFKIT----TSMQKDT PQELE--QTRSAVDE--DRKMYLQAAIVRIMKAR--KVLRHNALIQEVISQSRA------ --------RFNPSISMIKKCIEVLIDKQYIERSQAS-ADEYSYVA >Nematostella_vectensis_XM_001641104.1| . ELLAKYCDLILKKS----NKNLSDS-ELDEKLGEVIIVFKYIDDKDIFQK-FYSKMLAK- RLIHNLS----------------ISMDAEEAMISRLK--HACGY--EYTNRLHWMFT-DM SISSDLNSSFSDFL---------------------------------------------- ---ATAQVNMGINFSLLVLQSGAWPLGQTSV----------------------SPFSIPQ ELIRPVQMFEQFYNG-------------------------------------KFNGRKLA W-LQHLSNGEVKLNYCKR--------------------------------------TYFL TVSTFQMAVMLLFNDKLQ-----FTFSELSTLTQLLNKELTRIIQSLVDVK-----LLNK TEDD---------------DSKEATYSLNMNFS-------SKRTKLKIT----SAVQRDS PQVVILLSTRGTADSDNWHLHLAEKPMVRSYHLQ-QTNDTLFSFCLQVISQSRA------ --------RFIPSVPMIKKCIEALIDKQYLDRQEGS-KDEYSYVA >Trichoplax_adhaerens_XM_002110716.1| . EILARYADILLKKG----SKNWSDA-ELDDKQSHVINLFKYVDDKDLFQK-FYSKFLAK- RLIMNGS----------------ISLDAEEEMIKKLK--IICGY--EYTSRLHQMFT-DI RLNEGVNSEFSSYL---------------------------------------------- ---NKKNIKLTVNFSASVLQSGAWPLNQTSS-----------------------PYSIPP DLERSLTTFEEYYCTS------------------------------------LHRGRKLV W-LPYLSTAELRMTYLKK--------------------------------------GYYV TTTTYQMAVLLLYNNALS-----YTGRDIATWTQLTEKELIRTLSSLEAAK-----ILIK ENSR-----------------EGNSYKLNLEFG-------NKRTKFKIA----SSSIRES PQEIT--KVHSRIEE--ERKLFLQATIVRIMKSR--KVLNHNSLLEEVIKMSVN------ --------RFSPSIVLIKKCIELLIEKDYMKRNEGR-QDEYNYIA >Ciona_intestinalis_XM_002127350.1| . ELVCKYCDAILRRC----TKGPSND-ADE-KLQSSILVFRYIDEKDVFQK-FYSRALAR- RLIHSPC----------------A-MDMEEMMINRLK--GVCGY--DFTSKLHCMFT-DV RLSTELGKKYQETV---------------------------------------------- ---AKTEDSSQPSINVNVLQAGAWPLTANQV-----------------------EFVLPE TLHRCLKQFEEFYNH-------------------------------------KFNGRNLS W-LHHLSQAEVRINFTSK--------------------------------------PYLV SMSTYQLAIILLFNESIE-----LTVSDISQNTKLKDKDLERNIAALTDAN-----ILLK TTQEK--------------LEDMSVIRVNNKFS-------NKRTKFRVA---FTQTQKEQ STEVQ--QTHTAVAD--DRKLYLQAAIVRIMKAR--KVLHHNTLMEEVINKSRI------ --------RFTPSVSAIKRSIEALIEKSYIERSPDS-PDQYRYLA >Caenorhabditis_elegans_Z92822.2 . ERLARYTDGLLKKS----TKGLSET-DLEAKLDSAIVIFRYIEDKDIFQK-FYSKMLAN- RLIASTS----------------ISMDAEELMINKLK--QACGY--EFTSKLSRMFT-DI GLSQELSNNFDKHI---------------------------------------------A DIKTVQPDVKFVPTQTMILQAGSWPLNAPQL----------STNSNNQTAQDVANFHLPR ILQPVIQEFEKFYTG-------------------------------------KHNGRKLT W-LFNMSQGDVRLTYLDK--------------------------------------QYVA QMYVYQMAALLCFERRDA-----ILVKDIGEEIGVSGDYLLKTIRTILDVT-----LLTC DD---------------QNLTADSLVRLNMSMT-------SKRMKFRLQA-PQVNKAVEK EQEAV--ANT--VSW--DRKYYMECAIVRIMKTR--KVLKHNALVTEIMDQTKG------ --------RFSPDVPFIKKSIEDLIEKMYIQRTDQN--DEYQYLA >Brugia_malayi_XM_001900501.1| . ERLARYTDTLLRKS----GKGLSDG-ELDTKLTQAIIIFRYIEDKDIFQK-FYSKMLAN- RLITNAS----------------LSKDAEESMINKLK--QACGF--EFTSKLSRMFT-DV GLSHELTDKFVSHC---------------------------------------------- ---AVSNVTLNVQMAVLILQAGAWPLSAPNS-----TPTSGVDGKDSTTAVQVTGFIVPP VLLPSIEHFERYYQA-------------------------------------SHNGRKLT W-LFNLASVEVKLHYLDK--------------------------------------MYQV TMSVHQLAILLCFETRDS-----VTLSYIEKATGLSDELLSRNARALVDSG-----ILIM VKKE---------------MNEANEVALNLLLT-------SKRLRFKVL---VPQLQRHA EKEAE--HVNITAQQ--DRKYYMECTIVRIMKTR--KVLKHAALVNEVIEQTKS------ --------RFTPDVNFIKKNIESLIEKLYIQRTDQN--DEYQYLA >Caenorhabditis_briggsae_XM_001665917.1| . ELLARYCDQLLRKS----SKNPDEA-ELEDLLTKVMIVFKYIEDKDVFSK-FYTKMFSK- RLITDLS----------------ASDESEASFISKLK--SMCGY--EYTARLSKMVN-DT QVSKDLTAEFKEKK---------------------------------------------- ---SHLLGEKPIEFNVLVLSSGSWPTFPNST------------------------LTLPH QLSSTIDVFGQYYNE-------------------------------------KFNGRRLT W-VYSQSRGEVTSSAFSK--------------------------------------KYVF TVTTAQMCTLLLFNEQAS-----FTVQQISEATGLE----GKTCAGIAGS------LIKN LVLKSD------APLEGEEIPMTAAVSLNNSYT-------NKKVRVDLS---KMSLKQEA VRDTE--VVQKNAEE--DRKSLISACIVRIMKTR--KRVPHTQLMSEVITQLTG------ --------RFKPKVDVIKRCIGSLIEKEYMLRVEGQ-KDVYDYMA >Caenorhabditis_briggsae_XM_001680486.1| . -----FCDGMMRKG----TRIDGDL-EMEETQRKTANLLAYLNDKDIFIK-IFTKYFAR- RLINGQS----------------ASEEAETNFIAKLT--EAFGC--EYTFRLTKMVQ-DT QVSKDLSSEFKDQR---------------------------------------------- ---SKASRATKIEFGIQVLSTGTWPSFQLIN------------------------LNLPR DLTTTAERFSEFYIR-------------------------------------KFSGRKLS W-VHTQSRGEITSTAFKKK-------------------------------------KYVF GVTTPQMVIMLLFNEQLQ-----YSLDTIREASGMDQKSTQLVLGSLANSG-----ILKI GDSE-------------------GEVHLNLDYS-------NKKVRVDLS----RITVTQE TRETE--AVQKVVDE--NRTFIISAAIVRIMKMR--KQSTHQNLMTELIDQLKT------ --------RFKPKVELIKKCIGMMIEKEYIRRNKDD-RDIYEYMA >Caenorhabditis_elegans_cul-1_NM_066908.3| . ELLARYCDQLLRKS----SKMPDEA-ELEELQTKIMVVFKYIDDKDVFSK-FYTKMFSK- RLISELS----------------ASDEAEANFITKLK--SMCGY--EYTARLSKMVN-DT QVSKDLTADFKEKK---------------------------------------------- ---ADMLGQKSVEFNVLVLSSGSWPTFPTTP------------------------ITLPQ QLSKTIEIFGQFYNE-------------------------------------KFNGRRLT W-VYSQSRGEITSTAFPK--------------------------------------KYVF TATTAQMCTMLLFNEQDS-----YTVEQIAAATKMDEKSAPAIVGSLIKN------LVLK ADTELQ---------KEDEVPMTATVSLNKAYM-------NKKVRVDLS---KFTMKQDA VRDTE--NVQKNVEE--DRKSVISACIVRIMKTR--KRVQHQQLMTEVITQLSG------ --------RFKPKVEMIKRCIGSLIEKEYMLRTEGQ-KDLYEYLA >Caenorhabditis_briggsae_XM_001680487.1| . ELIARYCDLLMKKN----SKMPDEM-EMDVLQKNVITIFKYLEDKDIFMK-FYTKHFSK- RLLNEQS----------------ASDEAESSFISKLT--ECCGF--EYTSRLAKMVQ-DT QVSKDLSSGFKDQQ---------------------------------------------- --LESSRSKKSIEFGIQVLSTGTWPSMMLVN------------------------LNLPR DLSTTVEGFTAFYNT-------------------------------------KFTGRKLS W-IYNQSRGEITSTAFKGK-------------------------------------KYVF GATTTQMCTLLLFNEQLE-----YSAEKIQEATGLDTKTTQMVLGSLVKNQ-----VLKI KGAE--------DVKDADKVSMNADLVLNMGYS-------NKKVRVDLS---KMTMAVQT AKDQE--SVQKSMEE--DRKNIIQAAIVRIMKTR--KQCSHQKLMVELIEQLST------ --------RFKPKVELIKKCIGSLIEKEYLKRNEDQ-RDLYDYLA >Caenorhabditis_elegans_cul-6_NM_070011.2 . DYLARYCDQLLKKN----SKVQD-----ETALDKALTVLKYISEKDVFQL-YYQNWFSE- RIINNSS----------------ASDDAEEKFITNLT--ATEGL--EYTRNLVKMVE-DA KISKDLTTEFKDIK---------------------------------------------- -------TEKSIDFNVILQTTGAWPSLDQIK------------------------IILPR ELSTILKEFDTFYNA-------------------------------------SHNGRRLN W-AYSQCRGEVNSKAFEK--------------------------------------KYVF IVTASQLCTLYLFNEQDS-----FTIEQISKAIEMTAKSTSAIVGSLNPVIDP---VLVV DKGNEK-----------DGYPPDAVVSLNTKYA-------NKKVRVDLT---TAIKKATA DRETD--AVQNTVES--DRKYEIKACIVRIMKTR--KSLTHTLLINEIISQLKS------ --------RFTPNVQMIKICIEILIEQLYIRRSENE-HNVYEYLA >Oikopleura_dioica_AY449460.1 . ELVAKYCDSLLKRS----NKTIDEP-GTEEKFNQIMIVFKYIEDKDVFET-HYSRMFAN- RLIKGTS----------------GSDDAEESILQKLN--DICGF--EYTAKLNRMWQ-DI NTSKGTTEKFKKAL---------------------------------------------- ---QEEGIELGIDFSVKLLSTGSWPLTKAFS------------------------MELPG VLSNSLRVFKEHYDK-------------------------------------KNPRRTLT W-LCSQSKGEITANYQSK--------------------------------------NYVL VASTIQMAVLLLFNNENQ-----LTVAEISRRLAVDSTLMQQVVLVLLKHQ-----LLCL GPYPSLPE----TEGCDKLPGKEDLLSYNKDFF-------NKRTKITIN----VTYKIES HAEDP--VTTKNIEA--DRKLLIQAAIVRIMKTR--KQVNHSTLMSETINHLAS------ --------RFKPSVQKIKACVETLIEKEYIERVDG--KDVYIYVA >Aedes_aegypti_XM_001658738.1| . --LAKFCDALLKQC----LNTPEVV-KLDDALYTLMVLFKYIDDKDAFQK-LCSKMLVK- RLCNYMS----------------ANNHIKASIMSKLM--MAVSF--EYTSTLRCMFH-DI LVSHELNGQYKQQH---------------------------------------------- ---VQDLSDTNIDLNVQLLSSTFYQPNSNVK------------------------LMLPL ELEQCVTRYNDIYGH-------------------------------------RNPTRKLT W-LHNMSRGELTTNCFRM--------------------------------------QYTL QVNTFQMTILLQFNDQTS-----WTIHQLSENTGIDLDALIQSLRVLIESK-----LLKS QNNE-------------NSLLPSSSVELNTGFH-------NAESILNIN---YQIGSEMS AQQQE--ACQKQAEE--KNRFVIQAAIVRIMKQH--RTMNHSDLVAEVLKQLSK------ --------GLKPKVRAIKKAIDVLIEKEYLERQEGT-VDAYSYMG >Brugia_malayi_XM_001895703.1| . ELLARYCDLLLKKS----AKNPEEN-ELEELLNQIMIVFKYIEDKDVFQK-FYTKMLAK- RLVNELS----------------ASDEAESNMISKLK--QMCGF--EYTSKLQRMFT-DT SLSKDITERYKQYL---------------------------------------------- ---AAKNTNLGLDFSIMVLGSGVWPFSQSPI------------------------FDIPV QLTKCMESFNEFYQT-------------------------------------QHTGRKLT W-LLAQCRGELSAYGFQR--------------------------------------KYTF TATTAQMAVLMLYNENTE-----MTLQHICDSTKLRHEVVAQIAQALVKVE-----LLSI AGPKIDID---------VNTPLETVLRLNSHFS-------NKKLKVDLS---KTMARAEI RQETV--EVHKSVED--DRRLVVQAAIVRIMKMR--KKMKHTQLITEVLAQLAS------ --------RFKPKVPMIKKCIDILIEKEYLQRVENE-KDLYEYLA >Trichoplax_adhaerens_XM_002110125.1| . ELLARYCDSLLKKS----AKNPEED-ELDSALDDVMIVFKYIEDKDVFQK-FYARMLAK- RLVNQNS----------------ASDNAESAMISKLK--EACGY--EYTSKLQRMFQ-DM ELSKGLNEDFRKLP---------------------------------------------- ------NETNSVDFSVQVLSSGAWPFSPSPE------------------------FTVPS ELERSLQKFSGFYST-------------------------------------RHSGRKLN W-LFQLSKGELVTNCFKN--------------------------------------RYSL QVSTFQMAILLMYNRGDI-----FTVNELQQHTQLKMEILQQVLAILLKCK-----LLVC DDLDNS-----------GELKYNNRLELFLGYK-------NKKLRVNIN----VPLKTEQ KVERE--STHRNVEE--DRKLLIQAAIVRIMKMR--KVLQHQKLIAEVLTQLSS------ --------RFKPNVPVIKRCIDILIEKDYLQRVEGN-KDEYEYLA >Drosophila_willistoni_XM_002063514.1| . ELLAKYCDLLLKKS----SKNPEDK-ELEDNLNQVMVVFKYIEDKDVFQK-YYSKMLAK- RLVNHTS----------------ASDDAEAMMISKLK--QTCGY--EYTVKLQRMFQ-DI GVSKDLNSNFKEYL---------------------------------------------- ---ATKNVVPEIDFGIEVLSSGSWPFMLSNN------------------------FLLPS ELERSVRQFNEFYAA-------------------------------------RHSGRKLN W-LYQMCKGELIMNVIRNN----------------------------------ASTVYTL QASTFQMSVLLQFNDQLS-----FTVQQLLDNTQTQLENLIQVLQILLKAK-----VLTS SDNE-------------NSLTPESTVELFLDYK-------NKKRRININ----QPLKTEM KVEQE--TVHKHIEE--DRKLLIQAAIVRIMKMR--KRLNHTNLISEVLNQLST------ --------RFKPKVPVIKKCIDILIEKEYLERMEGH-KDTYSYLA >Drosophila_pseudoobscura_XM_001361440.2| . ELLAKYCDILLKKS----SKNPEDK-ELEDNLNQVMVVFKYIEDKDVFQK-YYSKMLAK- RLVNHTS----------------ASDDAEAMMISKLK--QTCGY--EYTVKLQRMFQ-DI GVSKDLNSNFKEHL---------------------------------------------- ---LTNNVVSEIDFGIEVLSSGSWPFQLSNN------------------------FLLPS ELERSVRQFNEFYAA-------------------------------------RHSGRKLN W-LYQMCKGELIMNVNRNN----------------------------------TSTVYTL QASTFQMSVLLQFNDQLS-----FTVQQLLENTQTQLESLIQVLQILLKAK-----VLTS TDNE-------------NSLTPESTVELFLDYK-------NKKRRININ----QPLKTEL KVEQE--TVHKHIEE--DRKLLIQAAIVRIMKMR--KRLNHTNLISEVLNQLST------ --------RFKPKVPVIKKCIDILIEKEYLERMEGH-KDTYSYLA >Drosophila_ananassae_XM_001960948.1| . ELLAKYCDLLLKKS----SKNPEDK-ELEDNLNQVMVVFKYIEDKDVFQK-YYSKMLAK- RLVNHTS----------------ASDDAEAMMISKLK--QTCGY--EYTVKLQRMFQ-DI GVSKDLNSNFKEYL---------------------------------------------- ---AGKNITTEIDFGIEVLSSGSWPFQLSNN------------------------FLLPS ELERSVRQFNEFYAG-------------------------------------RHSGRKLN W-LYQMCKGELIMNVNRNN----------------------------------TSTVYTL QASTFQMSVLLQFNDQLT-----FTVQQLLENTQTQQENLIQVLQILLKAK-----VLTS NDNE-------------NSLTPESTVELFLDYK-------NKKRRININ----QPLKTEL KVEQE--TVHKHIEE--DRKLLIQAAIVRIMKMR--KRLNHTNLISEVLNQLST------ --------RFKPKVPVIKKCIDILIEKEYLERMEGH-KDTYSYLA >Drosophila_yakuba_XM_002089504.1| . ELLAKYCDLLLKKS----SKNPEDK-ELEDNLNQVMVVFKYIEDKDVFQK-YYSKMLAK- RLVNHTS----------------ASDDAEAMMISKLK--QTCGY--EYTVKLQRMFQ-DI GVSKDLNSNFKQYL---------------------------------------------- ---AEKTVTMEIDFGIEVLSSGSWPFQLSNT------------------------FLLPS ELERSVRQFNEFYAA-------------------------------------RHSGRKLN W-LYQMCKGELIMNVNRNN-----------------------------------SSTYTL QASTFQMSVLLQFNDQLS-----FTVQQLQDNTQTQQENLIQVLQILLKAK-----VLTS SDNE-------------NSLTPESTVELFLDYK-------NKKRRININ----QPLKTEL KVEQE--TVHKHIEE--DRKLLIQAAIVRIMKMR--KRLNHTQLISEVLNQLST------ --------RFKPKVPVIKKCIDILIEKEYLERMEGH-KDTYSYLA >Drosophila_simulans_XM_002080465.1| . ELLAKYCDLLLKKS----SKNPEDK-ELEDNLNQVMVVFKYIEDKDVFQK-YYSKMLAK- RLVNHTS----------------ASDDAEAMMISKLK--QTCGY--EYTVKLQRMFQ-DI GVSKDLNSYFKQYL---------------------------------------------- ---AEKNLTMEIDFGIEVLSSGSWPFQLSNN------------------------FLLPS ELERSVRQFNEFYAA-------------------------------------RHSGRKLN W-LYQMCKGELIMNVNRNN-----------------------------------SSTYTL QASTFQMSVLLQFNDQLS-----FTVQQLQDNTQTQQENLIQVLQILLKAK-----VLTS SDNE-------------NSLTPESTVELFLDYK-------NKKRRININ----QPLKTEL KVEQE--TVHKHIEE--DRKLLIQAAIVRIMKMR--KRLNHTNLISEVLNQLST------ --------RFKPKVPVIKKCIDILIEKEYLERMEGH-KDTYSYLA >Drosophila_mojavensis_XM_002004166.1| . ELLAKYCDLLLKKS----SKNPEDK-ELEDNLNQVMVVFKYIEDKDVFQK-YYSNMLAK- RLVSHSS----------------ASDDAEAMMISKLK--QTCGY--EYTVKLQRMFQ-DI GLSKDLNAYFKEYL---------------------------------------------- ---KTQNITSEIDFGIEVLSTNAWPFTQNNN------------------------FLLPS ELERSVQQFTIFYSA-------------------------------------RHSGRKLN W-LYHKCKGELIMNVSRSN------------------------------------SVYTL QVSTFQMSVLLQFNDQLS-----FTVQQLCDNTQSQLENLIQVLQILLKAK-----LLTS ASSE-------------NGLTPDSTVELYLDYK-------SKKRRININ----HPLKTEL KVEQE--TVTKHIEE--DRKLLIQAAIVRIMKMR--KRLNHTNLISEVLNQLST------ --------RFKPNVPVIKKCIDILIEKEYLERMEGA-KDTYSYLA >Drosophila_grimshawi_AAPT01021501.1| . ELLAKYCDLLLKKS----SKNPEDK-ELEDNLNQVMVVFKYIEDKDVFQK-YYSNMLAK- RLVSHTS----------------ASDDAEAMMISKLK--QTCGY--EYTVKLQRMFQ-DI GVSKDLNSYFKEYL---------------------------------------------- ---KTQNITSEIDFGIEVLSTNAWPFTQNNN------------------------FLLPS ELERSVQQFTIFYSA-------------------------------------RHSGRKLN W-LYHKCKGELIMNVNRSN------------------------------------AVYTL QVSTFQMSVLLQFNDQLS-----FTVQQLRDNTQSQLENLIQVLQILLKAK-----VLTS SDSE-------------NALTPDSTVELFLDYK-------SKKRRININ----HPLKTEL KVEQE--TVTKHIEE--DRKLLIQAAIVRIMKMR--KRLNHTNLISEVLNQLST------ --------RFKPNVPVIKKCIDILIEKEYLERMEGH-KDTYSYLA >Anopheles_gambiae_XM_317457.3 . ELLAKYCDLLLKKS----SKNPEEA-ELEDTLNQVMVVFKYIEDKDVFQK-FYSKMLAK- RLCQHMS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNDQYRKHH--------------------------------------------EK LRDTRSTTQNEIDFSILVLSSGSWPFGQGFT------------------------FSLPF ELEQSVHRFNNFYAK-------------------------------------QHSGRKLN W-LYNMCRGELITNCFRM--------------------------------------RYTL QASTFQMAVLLQFNEETA-----WSIKQLGENTGINNENLIQVLPILLKTK-----LLNC YEGE-------------GKLHPDSTIELNKDFK-------NRKLRININ----FPLKSEL KVEQE--ATHKNIEE--DRKILIQAAIVRIMKMR--KMLNHTQLVNEVLNQLST------ --------RFKPKIQVIKKCIDILIEKEYLERQEGQ-KDTYSYLA >Culex_quinquefasciatus_XM_001844424.1| . ELLAKYCDLLLKKS----SKNPEEA-ELEDTLNQVMVVFKYIEDKDVFQK-FYSKMLAK- RLCHHMS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNEQYRQHV--------------------------------------------KG LREASKQTGNDIDFSILVLSSGSWPFNQSFT------------------------FSLPF ELEQSVHRFNNFYAK-------------------------------------QHSGRKLN W-LYNMCRGELITNCFRL--------------------------------------RYTL QASTFQMAVLLQFNEQKS-----WTIQQLGENTSINQESLIQVLQILLKSK-----LLTS SDDE-------------ANLTTSSSVELNTGFK-------NKKLRININ----FPLKTEL KVEQE--ATHKHIEE--DRKILIQAAIVRIMKMR--KVLNHTCLVGEVLNQLST------ --------RFKPKVQVIKKCIDILIEKEYLERQEGQ-KDTYSYLA >Aedes_aegypti_XM_001663670.1| . ELLAKYCDLLLKKS----SKNPEEA-ELEDTLNQVMVVFKYIEDKDVFQK-FYSKMLAK- RLCHHMS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNEQYKTYV-------------------------------------------KGL REATRQQTGNEIDFSILVLSSGSWPFNQSFT------------------------FSLPF ELEQSVHRFNSFYAK-------------------------------------QHSGRKLN W-LYNMCRGELITNYFRM--------------------------------------RYTL QASTFQMAVLLQFNEQES-----WTIQQLSENTGINHENLIQVLQILLKTK-----LLQS YDDE-------------ANLQPASSVELNQGFK-------NKKLRININ----FPLKTEL KVEQE--ATHKHIEE--DRKILIQAAIVRIMKMR--KALNHTHLVGEVLNQLST------ --------RFKPKVQVIKKCIDILIEKEYLERQEGQ-KDTYSYLA >Ciona_intestinalis_XM_002123456.1| . -------DTLLKSA-----KVSEDA-ELEATLKEVLTVFRYIEDKDVFQT-FYSKMLAR- RLVQHTS----------------ASDDAEAQMISRLK--QTCGF--EYTSKLQRMFQ-DV DVSKNLNERFRTHI---------------------------------------------- ----AASTPLDLDFSIQVLSSGSWPFQQSVT------------------------FRLPV ELERSYQRFTTFYSQ-------------------------------------AHNGRKLS W-LYQMSKGEIVTNCFKN--------------------------------------RYTF QASTFQMAILLQYNSATS-----YTVQQLAENTQLKMEILLQVLIHLLKCK-----ILQC KDEPDA-----------NNLKPHNEIELFLGYR-------SKKLRVNIN----KPVKTEQ KQEQE--VTHKHIEE--DRKMLIQAAIVRIMKMR--KQQKHQQLLSEVLSQLSS------ --------RFKPRVPIIKKCIDTLIEKEYLERVEGE-KDMYQYLA >Nasonia_vitripennis_XM_001606779.1| . ELLAKYCDVLLKKS----SKNPEEA-ELEDTLNQVMVVFKYIEDKDVYQK-FYSKMLAK- RLVQHMS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNEHFRRHL---------------------------------------------- ---TNSAEPLDIDFSIQVLSSGSWPFQQSFT------------------------FSLPT ELERSVHRFTSFYSS-------------------------------------QHSGRKLN W-LYNMSKGELHTNCFKN--------------------------------------RYTL QASTFQMAVLLQYNTSTS-----WTIQQLHESTQIKMDFLLQVIQILLKAK-----LLVT SDDE-------------SELGPTSTVDLFTGYK-------NKKLRVNIN----IPMKTEL KIEQE--TTHKHIEE--DRKLLIQAAIVRIMKMR--KVLKHQQLVAEVLNQLSI------ --------RFKPRVHVIKKCIDILIEKEYLERTEGQ-KDTYSYLA >Apis_mellifera_XM_394044.3 . ELLAKYCDLLLKKS----SKNPEEA-ELEDTLNQVMVVFKYIEDKDVFQK-FYSKMLAK- RLVQHMS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNEQFRRHL---------------------------------------------- ---TNSAEPLDIDFNIQVLSSGSWPFQQSFT------------------------FSLPT ELERSVHRFTTFYSS-------------------------------------QHSGRKLN W-LYNMSKGELHTNCFKN--------------------------------------RYTL QASTFQMAVLLQYNGSTV-----WTIQQLHDATQIKMDFLLQVIQILLKAK-----LLTA ATDDE------------AELTPLSTVELFTGYK-------NKKLRVNIN----IPMKTEL KIEQE--TTQKNIEE--DRKLLIQAAIVRIMKMR--KVLKHQQLVAEVLNQLSS------ --------RFKPRVHVIKKCIDILIEKEYLERTEGQ-KDTYSYLA >Tribolium_castaneum_XM_966883.1| . ELLAKYCDLLLKKS----SKNPEEA-ELEDTLNQVMVVFKYIEDKDVFQK-FYSKMLAK- RLVQHMS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNEQFKSHL---------------------------------------------- ---LKSNETLDIDFSIQVLSSGSWPFQQSFT------------------------FGLPT ELERSVHRFTNFYSG-------------------------------------QHSGRKLN W-LYNMSKGELHTNCFKN--------------------------------------RYTL QASTFQMAVLLQFNVSES-----WTIAQLEENTQIKTDFLIQVIQILLKAK-----LITC DDDE-------------NELAPHSVVNLFLGYK-------NKKLRVNIN----IPMKTEL KMEQE--TTHKHIEE--DRKLLIQAAIVRIMKMR--KILKHQQLVAEVLNQLSS------ --------RFKPRVHIIKKCIDILIEKEYLERTEGQ-KDTYSYLA >Acyrthosiphon_pisum_XM_001952398.1| . EMLAKFCDLLLKKS----SKNPEEA-ELEDTLNQVMIMFKYIEDKDVFQK-FYSKMLAK- RLVQHMS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNEAFRKHV---------------------------------------------- ---ANSNMPHDIDFSIQVLSSGSWPFQYLLT------------------------FSLPS ELERSVQRFTQFYSA-------------------------------------QHSGRKLN W-LYNMSKGELVTNCFKN--------------------------------------RYTL QASTFQMAVLLQFNVQES-----WTVNQLSESTQLKTDYLIQVVQILLKAK-----LLTC NEDE-------------ANVEGNSLVKLFLGYK-------NKKLRVNIN----VPMKQEI KLEQE--STHKHIEE--DRKMLIQAAIVRIMKMR--KVMKHQQLTAEVLTQLSS------ --------RFKPRVNVIKKCIDILIEKEYLERTEGQ-KDSYSYLA >Pediculus_humanus_AAZO01006645.1| . ELLARYCDMLLKKS----SKNPEES-EVEETLNQLMVVFKYIEDKDVFQK-FYSKMLGK- RLVQRMS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNEQFRIYL---------------------------------------------- ---ENSEDTTDIDFGIQVLSSGSWPFQQSYS------------------------FFLPA ELERSVHMFTTFYSS-------------------------------------QHSGRKLN W-LFHMSKGELVTNCFKT--------------------------------------RYTL QASTFQMAVLLQYNTSSS-----WTVQQLEELTQLKSDILIQVLQILLKTK-----LLET DNSE-------------SDLQSTSLLKLSENFK-------NKKLRVNIN----IPMKAEL KTEQE--VTQKHIEE--DRKLLVQAAVVRIMKMR--KVLKHQQLVAEVLNQLNS------ --------RFKPKVNTIKKCIDILIEKEYLERTEGQ-KDTYSYLA >Nematostella_vectensis_XM_001629583.1| . ELLARYCDSLLKKS----SKNPEEA-ELEDILNSVMVVFKYIEDKDVFQK-FYANMLAK- RLVQHNS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNDKFKAHL---------------------------------------------- ----ANTGSLDLDFTIQVLSSGSWPFQQSWT------------------------FSLPA EMEKSHQRFTTFYSS-------------------------------------QHSGRKLH W-LYHKSKGELVTNCFKN--------------------------------------RYTL QASTYQMGVLLMFNTADS-----YTVEQIQEQTQLKMELLIQVLGILLKTK-----LLLC DTCED-----------VSGLEPSSVLKLFFGYK-------NKKLRVNIN----VPMKTEQ RNEQE--QTHKYIEE--DRKLLIQAAIVRIMKMR--KMLKHQPLLAEVLSQLSS------ --------RFKPRVPTIKKCIDILIEKEYLERVEGE-KDTYAYLA >Branchiostoma_floridae_XM_002221807.1| . ELLARYCDSLLKKS----SKNPEEA-ELEDTLNQVMIVFKYIEDKDVFQK-FYAKMLAK- RLVQHNS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNEQFKKHL---------------------------------------------- ---EKSGEPLDVDFSIQVLSSGSWPFQQGAS------------------------FTLPS ELERSFQRFTTFYSS-------------------------------------QHSGRKLM W-LYHMSKGELVTNCFKN--------------------------------------RYTL QASTFQMSVLLQFNQADS-----YTVQQLHEHTQLKMDILQQVLAILLKAK-----LLVS EDQE-------------EELKSESVVSLFLGYK-------NKKLRVNIN----VPMKTEQ KQEQE--TTHKHIEE--DRKLLIQAAIVRIMKMR--KVLKHQQLLGEVLTQLSS------ --------RFKPRVPVIKKCIDILIEKEYLERVDGE-KDTYSYLA >Strongylocentrotus_purpuratus_XM_789267.2| . ELLAKYCDSLLKKS----SKNPEEA-ELEDTLNQVMVVFKYIDDKDVFQK-FYSKMLAK- RLVHHNS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GLSKDLNEQFKNHL---------------------------------------------- ----ASSESLDIDFSIQVLCSGSWPFQQGCT------------------------FNLPS ELERSFQRFTTFYGS-------------------------------------QHSGRKLM W-IFQMSKGELVTSCFKN--------------------------------------RYTL QASTFQMAVLLQFNVSDS-----YTIQQLHDSTQIKMDILTQVIQILLKCK-----LLVG DDGD-------------DELKPTTEVKLYQGYK-------NKKLRVNIN----VPMKTEQ KQEQE--TTHKHIEE--DRKLLIQAAIVRIMKMR--KALRHQQLLSEVLTQLSG------ --------RFKPKVPVIKKCIDILIEKEYLERVDGE-KDVYSYLA >Bos_taurus_XM_589507.2 . ELLAQYCDSLLKKS----SKNPEEA-ELEDTLNHVMTVFKYMDDKDVVQK-FYTKMLAK- RLVHQNS----------------ASDDAEASMVSKLK--QACGF--EYTSKLQRMFQ-DI GVSKALNAQFKKHL---------------------------------------------- ----MDSEPLDLDFSIHVLSYGWWPFEESCT------------------------VLLPS ELEPCYRRFTAFYAS-------------------------------------CYSDRKLS W-AYQLSEGELVTNYFKN--------------------------------------NYTL RVSTFQMAILLQYNTEDA-----YTIQQLMDSTQIKMDIVAQVLQILLKFK-----LLVL EDKSAN--------VDEVELKPDTLIKLHFGYK-------SKKLRVNIS----LPMKIEQ KREQE--TMYKNIEE--DRKLLIQAAIVRIMKMR--KVVKHQQLLGEVATQLSS------ --------VFKPQISVIKKCIDILIEKEYLERVGDE-KDTYSYLA >Tursiops_truncatus_ABRN01250400.1| . ELLAGYCDSLLKKR----SKNPEEA-ELEDTLNQAIAVFKYIEDRDVFQK-FYAKMLAK- RFVHQNS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GASKYLNEWFKKHP---------------------------------------------- ----TNSEPLGLDFSIQVLSSRSWPSQQSGT------------------------FALPS ELERSYQRLTAFYAS-------------------------------------RHSGRKLT W-LYQLSEGELVTNCFKN--------------------------------------RYTL QASTFRMAILLRYNTEDA-----HAVQQLMDSTQIKTDIFAQVLQILLKLK-----LLVL EDENTP--------VDEMELKQDTLIKLYLGYR-------NKKLRVNIN----VPMKMEQ KQEQE--TTHRNTEA--DRKLLIQAALVRIMKMR--KVLKHQQLLGEVLTQLSS------ --------IFKPRIPVIKKCIDILIAKEYLER------------- >Otolemur_garnettii_AAQR01731211.1| . ELLARYCDSLLKKS----SKNPEEA-ELEDTLNQVMIVFKYIDDKDVFHK-FYAKMLAK- RLVHHNS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNEQFKKHL---------------------------------------------- ----TNSEPLDLDFSIQVLSSGSWPFQQSCT------------------------FSLPS ELERSYQRFTAFYAS-------------------------------------RHSGRKLT W-LYQLSKGELVTNCFKN--------------------------------------RYTL QASTLQMAILFQYNTQDA-----YTVQQLTDSTQIKMDILVQVLHILLKSK-----LLVM ENENVN----------ELELKPDTLIKLYLAYK-------NKKLRVNIN----VPMKTEQ KQEQE--TTHKIIEE--DRKLLIQAAIVRIMKMR--KVLKHQQLLGEVLTQLSS------ --------RFKPRVPMIKKCIDILIEKEYLERVDGE-KDTYSYLA >Danio_rerio_Cul1b_BC165368.1| . ELLARYCDSLLKKS----SKNPEEA-ELEDTLNQVMVVFKYIEDKDVFQK-FYAKMLAK- RLVHQNS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNEQFKKHL---------------------------------------------- ----SNSEPLDLDFSIQVLSSGSWPFQQSCT------------------------FALPS ELERSYQRFTAFYGS-------------------------------------RHSGRKLT W-LYHLSKGELVTNCFKN--------------------------------------RYTL QASTFQMAILLQFNTENC-----YSVQQLADSTQIKTDILVQVLQILLKSK-----LLVL EDENAN--------IDEMDFKPDTLIKLFLGYK-------NKKLRVNIN----VPMKTEQ KQEQE--TTHKNIEE--DRKLLIQAAIVRIMKMR--KVLKHQQLLAEVLNQLSS------ --------RFKPRVPVIKKCIDILIEKEYLERVDGE-KDTYSYLA >Danio_rerio_Cul1a_BC066480.1 . ELLARYCDSLLKKS----SKNPEEA-ELEDTLNQVMVVFKYIEDKDVFQK-FYAKMLAK- RLVHQNS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNEQFKKHL---------------------------------------------- ----TNSEPLDLDFSIQVLSSGSWPFQQSCT------------------------FALPS ELERSYQRFTAFYAS-------------------------------------RHSGRKLT W-LYHLSKGELVTNCFKN--------------------------------------RYTL QASTFQMAILLQYNTEDV-----YTVQQLTDSTQIKIDILVQVLQILLKSK-----LLVL EDENAN--------VDEVEFKPDTLIKLFLGYK-------NKKLRVNIN----VPMKTEQ KQEQE--TTHKNIEE--DRKLLIQAAIVRIMKMR--KVLKHQQLLAEVLNQLSS------ --------RFKPRVPVIKKCIDILIEKEYLERVDGE-KDTYSYLA >Xenopus_laevis_BC097675.1| . ELLARYCDSLLKKS----SKNPEEA-ELEDTLNQVMVVFKYIEDKDVFQK-FYAKMLAK- RLVHQNS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNEQFKKHL---------------------------------------------- ----TNSEPLDLDFSIQVLSSGSWPFQQFCT------------------------FALPS ELERSYQRFTAFYAS-------------------------------------RHSGRKLT W-LYQLSKGELVTNCFKN--------------------------------------RYTL QASTFQMAILLQFNTEDA-----YTVQQLTDSSQIKMDILVQVLQILLKSK-----LLVL EDENAN--------VDDVDLKPDILIKLYLGYK-------NKKLRVNIN----VPMKTEQ KQEQE--TTHKNIEE--DRKLLIQAAIVRIMKMR--KVLKHQQLLGEVLTQLSS------ --------RFKPRVPVIKKCIDILIEKEYLERVDGE-KDTYSYLA >Myotis_lucifugus_AAPE01530379.1| . ELLARYCDSLLKKS----SKNPEEA-ELEDTLNQVMVVFKYIEDKDVFQK-FYAKTLAK- RLVHQNS----------------ASDDAEASMISKLK--QACGY--EYTSKLQRMFQ-DI GVSKDLNEQFKKHL---------------------------------------------- ----TNSEPLDLDFSIQVPSSGSWPFQQSCT------------------------FALPS ELERSYQRFTAFYAS-------------------------------------RHSGRKLT W-LYQLSKGELVTNCFKN--------------------------------------RYTL QASTFQMAILLQYNTEDV-----YSVQQLTDSTQIKMDILAQVLQILLKSK-----LLVL EDENAN--------VDEVELKPDTLIKLYLGYK-------NKKLRVNIN----VPMKTEQ KQEQE--TTHKNIEE--DRKLLIQAGIVRIMKMR--KVLKHQQLLGEVLTQLSS------ --------RFKPRVPVIKKCIDILIEKEYLERVDGE-KDTYSYLA >Mus_musculus_CUL1_BC029260.1 . ELLARYCDSLLKKS----SKNPEEA-ELEDTLNQVMVVFKYIEDKDVFQK-FYAKMLAK- RLVHQNS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNEQFKKHL---------------------------------------------- ----TNSEPLDLDFSIQVLSSGSWPFQQSCT------------------------FALPS ELERSYQRFTAFYAS-------------------------------------RHSGRKLT W-LYQLSKGELVTNCFKN--------------------------------------RYTL QASTFQMAILLQYNTEDA-----YTVQQLTDSTQIKMDILAQVLQILLKSK-----LLVL EDENAN--------VDEVELKPDTLIKLYLGYK-------NKKLRVNIN----VPMKTEQ KQEQE--TTHKNIEE--DRKLLIQAAIVRIMKMR--KVLKHQQLLGEVLTQLSS------ --------RFKPRVPVIKKCIDILIEKEYLERVDGE-KDTYSYLA >Choloepus_hoffmanni_ABVD01464848.1| . ELLARYCDSLLKKS----SKNPEEA-ELEDTLNQVMVVFKYIEDKDVFQK-FYAKMLAE- RLVHRNS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNEQFKKHL---------------------------------------------- ----TNSEPLDLDFSIQVLSSGSWPFQQSCT------------------------FALPS ELERSYQRFTAFYAS-------------------------------------RHSGRKLT W-LYQLSKGQLVTNCFKN--------------------------------------RYTL QASTFQMAILLQYNTEDA-----YMVQQLTDSTQIKMDILAQVLQILLKSK-----LLVL EDENTN--------VDEVELKPDTLIKLFLGYK-------NKKLRVNIN----VPMKTEQ KQEQE--TTHKNIEE--DRKLLIQAAIMRIMKMR--KVLKHQQLLGEVLTQLSS------ --------RFKPRVPVIKKCIDILIEKEYLERVDGE-KDTYSYLA >Monodelphis_domestica_XM_001363127.1| . ELLARYCDSLLKKS----SKNPEEA-ELEDTLNQVMVVFKYIEDKDVFQK-FYAKMLAK- RLVHQNS----------------ASDDAEASMISKLK--QACGF--EYTSKLQRMFQ-DI GVSKDLNEQFKKHL---------------------------------------------- ----TNSEPLDLDFSIQVLSSGSWPFQQSCT------------------------FALPS ELERSYQRFTAFYAS-------------------------------------RHSGRKLT W-LYQLSKGELVTNCFKN--------------------------------------RYTL QASTFQMAILLQYNTEDA-----YTVQQLTDSTQIKMDILAQVLQILLKSK-----LLVL EDENAN--------VDEVELKPDTLIKLFLGYK-------NKKLRVNIN----VPMKTEQ KQEQE--TTHKNIEE--DRKLLIQAAIVPIMKMR--KVLKHPQLLGEILTQLSS------ --------RFKPRVPVIQKCIDILIEKEYLERVDGE-KDTYSYLA >Fugu_rubripes_CAAB01001844.1 . ERFAQYIDQIIQSSG-MACGNMAALDRLQQFLEP-MLLLSGLELANTFEH-FYRYYLGD- RLLAQAN-VWLETTVVDQIGSCFPSRFPQQ-MLKNLS--ESADL--RQEFHLYRLQQLDR RLQEQDQMMEDWVE---------------------------------------------- -------SEEEAEVQVLVVSPRYWAVSALCF-------------------LDEPAKYFPA ELCSYLNQFTQFYSHSQYMYSLS-----------------------------HSKPRRLQ W--TWLGHAELQ--FG----------------------------------------RSTL HVSTLQMFILLQFNKHQE-----VRVDSLLEETGLSSAMLLHALQLLVDKGGP---LTCS RP---------------DDPTQGVLKLSQQVVPD---SADGVPACVSLLP-----KQTYL NVNED---AAGTLER---KRNYIYCLIVHILKRE--KEMHIDNLVFKVMESCQKQDGVPS ----VGGGRFSCATSDVLSCIMHVICRGCARRNEEN-PHIVEFLP >Danio_rerio_XM_001339319.2| . ERFAQYIDKMIQESG-VDSGSVDTLNQLQQFLEP-MLFLSGLELANTFEH-FYRYYLGD- RLLGQGK-VWLENAVVEQIGTCFPNRFPQQ-MLTNLS--ESEEL--QQEFHLYRLQQLDR NLEDFEEMM--------------------------------------------------- -DEDVPEPEEESDVKVLVLSPRCWVVSAPCY-------------------LQDPSKHFPA QLCNYLAEFTDFYTNSQRMYSLT-----------------------------HSKPRRLQ W--TWLGHAELQ--YG----------------------------------------SCTL YVSTLQMFILLQFNQHED-----VSVEMLQQATGLSPAMLSHALKPLTAEKG----LLTH TGSS-------------QDPIKGILRLNKNTLSQ----SSDRHGYHYLHP-----KQTYL NVDED---AALTLER---KRNYIYCLIVQIMKNE--KEMHIDNLVFQVLDRCQKQESNRT ----RTSVRFSCSTTDVLSCIMHVINKGYLRRNDES-PHIVEF-- >Xenopus_tropicalis_BC124567.1| . EQFARYIDCRIQEIS-TDYYNLQALGHLQQFLEF-VLFLSDLELANSFEH-FYRHYLAD- RLLSLGP-SWLESSVVDHIGICFPNRFPQQ-MLKNLQ--EASDL--QREQHLFCLQEMDT GLLSDEEGEDMEEEK--------------------------------------------- -SIGVGHLGEEPKVHISVLSPRCWAIPSLCY-------------------MKDPTKYFPE SLCRPLNCFKDFYTKSQSLQGSD-----------------------------LTQSRRLQ W--TWLGNAEVQ--YG----------------------------------------SLTL QVSTLQMFILLQFNQREE-----VSFESITQATGLSQVLIGHALSPLTAKGA----ILTQ EEG--------------------YLRVNGEARSE-----PGAGRVLRLLP-----RQTYL NVEED---EGRTLER---KRNVIFCLITQIMKEE--KELHIDNLVFRVIEACQKMESGRS ----LKFLSFGCSHTDVLSCIMHLISQGYVRRSDDR-PHILEY-- >Gallus_gallus_XM_419326.2| . ERFARYLDRKVRELH-GAA-GGAG--QLQQILEP-FVVFGGLEFAHTFEH-FYRLYLGD- RLLAQGP-SWLEGAAVEQMGLCFPRRFPQE-MLSDLA--ASEEL--RRHFGLFRLQERDR RLLERGLGTESPEA---------------------------------------------- EVPGEAPAADALEVEVLVLSPRCWPVSPLCY-------------------VEEPRRFFPA ALSSPLDEFADFWRHSECGGGGVGALSRRCGGTGSAHVADAALAGQSRPGWVCSRPRRLQ W--TWLGHAELR--FG----------------------------------------DCVL HVSTLQMYILLRFNSAEE-----VAVEALLQATGLPAELVHQALAPLTHGDG----ILVQ SCTQ---------------GAPGALRLNRAALAH------ASGRHLRLLP-----QQRYL RAERA---ESSALER---KRNVLCCLITRILKAE--KQLHIDNLVFKVIDACEKGELGLG ----QQFLSFCCHSVDVLSCVLHLLNQGYLRRQDER-PQVLEY-- >Pan_troglodytes_XM_001136655.1| . EQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQA-VLIFSGLEIATTFEH-YYQHYMAD- RLLGVVS-SWLEGAVLEQIGPCFPNRLPQQ-MLQSLS--TSKEL--QRQFHVYQLQQLDQ ELLKLEDTEKKIQVGLGASGKEHKSEKEEEAG-------------AAAVVDVAEGEEEEE ENEDLYYEGAMPEVSVLVLSRHSWPVASICH-------------------TLNPRTCLPS YLRGTLNRYSNFYNKSQSHPALE-----------------------------RGSQRRLQ W--TWLGWAELQ--FG----------------------------------------NQTL HVSTVQMWLLLYLNDLKA-----VSVESLLALSGLSADMLNQAIGPLTSSRGP---LDLH EQKD---------------IPGGVLKIRDGSKEP-----RSRWDIVRLIP-----PQTYL QAEGE---EGRNLEK---RRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPR GLVSSLGKGSACSSTDVLSCILHLLGKGTLRRHDDR-PQVLSYAV >Pongo_abelii_CR858277.1 . EQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQA-VLIFSGLEIATTFEH-YYQHYMAD- RLLGVVS-SWLEGAVLEQIGPCFPNRLPQQ-MLQSLS--TSKEL--QRQFHVYQLQQLDQ ELLKLEDTEKKIQVGHGASGKEHKSEKEEEAG-------------AAAAVDVAEGEEEEE ENEDLYYEGAMPEVSVLVLSRHCWPVASICH-------------------TLNPRTCLPS YLRGTLNRYSNFYNKSQSHPALE-----------------------------RGSQRRLQ W--TWLGWAELQ--FG----------------------------------------NQTL HVSTVQMWLLLYLNDLKA-----VSVESLLALSGLSADMLNQAIGPLTSSRGP---LDLH EQKD---------------IPGGVLKIRDGSKEP-----RSRWDIVRLIP-----PQTYL QAEGE---EGRNLEK---RRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPR GLVSSLGKGSACSSTDVLSCILHLLGKGTLRRHDDR-PQVLSYAV >Homo_sapiens_NM_014780.3_CUL7 . EQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQA-VLIFSGLEIATTFEH-YYQHYMAD- RLLGVVS-SWLEGAVLEQIGPCFPNRLPQQ-MLQSLS--TSKEL--QRQFHVYQLQQLDQ ELLKLEDTEKKIQVGLGASGKEHKSEKEEEAG-------------AAAVVDVAEGEEEEE ENEDLYYEGAMPEVSVLVLSRHSWPVASICH-------------------TLNPRTCLPS YLRGTLNRYSNFYNKSQSHPALE-----------------------------RGSQRRLQ W--TWLGWAELQ--FG----------------------------------------NQTL HVSTVQMWLLLYLNDLKA-----VSVESLLAFSGLSADMLNQAIGPLTSSRGP---LDLH EQKD---------------IPGGVLKIRDGSKEP-----RSRWDIVRLIP-----PQTYL QAEGE---DGQNLEK---RRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPR GLVSSLGKGSACSSTDVLSCILHLLGKGTLRRHDDR-PQVLSYAV >Macaca_mulatta_XM_001088003.1| . EQFARHIDQQIQGSRIGGAQEMERLAQLQQCLQA-VLIFSGLEIATTFEH-YYQHYMAD- RLLGVVS-SWLEGAVLEQIGPCFPNRLPQQ-MLQSLS--TSKEL--QRQFHVYQLQRLDQ ELLKLEDTEKKIQVGHRDSGKEYKSEKEEGAG-------------AAAAVDVTEGEEEEE ENEDLYYEGAMPEVSVLVLSRHCWPVASICH-------------------TLNPRTCLPS YLRGTLNRYSNFYNKSQSHPALE-----------------------------QGSQRRLQ W--TWLGWAELQ--FG----------------------------------------NQTL HVSTVQMWLLLYLNDLKA-----VSVESLLALSGLSEDMLNEAIGPLTSSRGP---LDLH EQKD---------------IPGGVLKIRDGSKEP-----RSRWDIVRLIP-----PQTYL QAEGE---EGRNLEK---RRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPR GLVSSLGRGSACSSTDVLSCILHLLGKGTLRRHDDR-PQVLSYAV >Canis_familiaris_XM_538928.2 . EQFARHIDQRIQGSRIGGARGMEMLAQLQRCLET-VLIFSGLEIATTFEH-YYQHYMAD- RLLGVGS-SWLEGAVLEQIGPCFPNRLPQQ-MLQSLS--TSEEL--QRQFHVYQLQRLDQ ELLKLEDTEKKIQGGHETSDKEHKGEKAEEAE-------------GAVVTNVVEEEEEEE ENEDLYYEGAMPEVSVLVLSPRCWPIASICH-------------------TLNPRTCLPS YLRGTLNRYSNFYSKSQSYPALE-----------------------------QGPKRRLQ W--TWLGRAELQ--FG----------------------------------------DQTL HVSTVQMWLLLYLNDLQA-----VSVESLLALSGLSPDMLNQAITPLTSLRGP---LDLR EEND---------------VPGGVLKIRDASEEP-----RPRRGNVWLIP-----PQVYL KAEDE---EGRNLEK---RRNLLNCLIVRILKAHGDKGLHIDQLVCRVLDAWQKGPCPPR GLVSSLGRGSACNSTDVLSCILHLLGKGTVRRHDDQ-PQMLSYAV >Equus_caballus_XM_001497361.2| . EQFARHIDQRIQGSRIGGARGMEMLAQLQRCLET-VLVFSGLEIATTFEY-YYQHYMAD- RLLGVGS-SWLEGAVLEQIGLCFPNRLPQQ-MLRSLS--TSEEL--QRQFHVYQLQRLDQ ELLKLEDTEKKMQGGHGASGKEYERENEEEAE----------EAGAAAAAADKAEVEEEE ENEDLYYEGAMPEVSVLVLSPRCWPIASICH-------------------TLNPKICLPS YLRGTLNRYSNFYNKSQSYPVVE-----------------------------RGPQRRLQ W--TWLGRAELQ--FG----------------------------------------DQTL HVSTVQMWLLLYLNDLKE-----VSVESLLALSGLSQDMLNQAIGPLTSLRGP---LDLH EQKD---------------VPGGVLKIRDASEEP-----RPRRGNVWLIP-----PQTYL KAEDE---EGRNLEK---RRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPR GLVSSLGRGSACSSTDVLSCILHLLGKGTVRRHDDR-PQTLSYAV >Bos_taurus_XR_042848.1| . EQFAQHIDQRIQGSWIGGARGMEMLAQLQLCLET-ILIFSGLEIATTFKH-YYQHYMAD- RLLGVGS-SWREGAVLEQIGPCFPNRLPQQ-MLQSLS--TSEEL--QHQLHVYQLQRLDQ ELLKLEDTEKKIQVSRDASGRGHERGTGEEAE----------LEAAALAAAATASVAGEE EGEDLYYEGAMPEVSVLVLSPRCWPTASICH-------------------TLNPRTCLPA YLRG-TLNYSNFYNKCQSCPALE------------------------------GPQRRLQ W--TWLGRAELQ--FG----------------------------------------DQML HVSTMQMWLLLHFNKLKA-----VFVESLLALSGLPPDMLNQAVGPLTSSRGP---LDLD ETKD---------------TPAGLLKIRDGSEEP-----RPRRGNVWLIP-----AQTYL KVEDE---EGRNLEK---RRNLLNCLIVRILKAHGDEGLHVSQVVCLVLEAWQKGPCPPR GLVSNFGRGSTCGSADVLSCILYLLGKGTVRRQDDR-PQMLSYAV >Bos_taurus_XM_580700.4| . EQFARHIDQRIQGSRIGGARGMEMLAQLQRCLET-VLIFSGLEIATTFEH-YYQHYMAD- RLLGVGS-SWLEGAVLEQIGPCFPTRLPQQ-MLRSLS--TSEEL--QRQFHVYQLQRLDQ ELLKLEDTEKKIQVGAGEGTKRGTGEEAELEAG------AVAAAAAAGVAGEEEEEEEED ESEDLYYEGAMPEVSVLVLSPRCWPTASICH-------------------TLNPRTCLPA YLRGTLNRYSNFYNKRQTYPALE-----------------------------RAPQRRLQ W--TWLGRAELQ--FG----------------------------------------DQTL HVSTVQMWLLLHFNELKA-----VSVESLLSLSGLPPDVLNQAVGPLTSSRGP---LDLD ETKD---------------TPAGLLKIRDSSEEP-----RPRRGNVWLIP-----AQTYL KAEDE---EGRNLEK---RRNLLNCLIVRILKAHGDEGLHIDQLVCLVLEAWQKGPCPPR GLVSSLGRGSTCGSADVLSCILHLLGKGTVRRQDDR-PQMLSYAV >Mus_musculus_NM_025611.5| . EQFARHIDQRIQGSRMGGARGMEMLAQLQRCLES-VLIFSPLEIATTFEH-YYQHYMAD- RLLSVGS-SWLEGAVLEQIGPCFPSRLPQQ-MLQSLN--VSEEL--QRQFHVYQLQQLDQ ELLKLEDTEKKIQVAHEDSGREDKSKKEEAIGE-AAAVAMAEEEDQGKKEEGEEEGEGED EEEERYYKGTMPEVCVLVVTPRFWPVASVCQ-------------------MLNPATCLPA YLRGTINHYTNFYSKSQSRSSLE-----------------------------KEPQRRLQ W--TWQGRAEVQ--FG----------------------------------------GQIL HVSTVQMWLLLHLNNQKE-----VSVESLQAISELPPDVLHRAIGPLTSSRGP---LDLQ EQKN---------------VPGGVLKIRDDSEEP-----RPRRGNVWLIP-----PQTYL QAEAE---EGRNMEK---RRNLLNCLVVRILKAHGDEGLHVDRLVYLVLEAWEKGPCPAR GLVSSLGRGATCRSSDVLSCILHLLVKGTLRRHDDR-PQVLYYAV >Rattus_norvegicus_NW_047813.2 . EQFARHIDQRIQGSRMGGARGMEMLAQLQRCLES-VLILSPLEIATTFEH-YYQHYMAD- RLLSVGS-SWLEGAVLEQIGPCFPGRLPQQ-MLQTLN--ISEEL--QRRFHVYQLQQLDQ ELLKLEDTEKKIQEEEEGKKEE-------------------------GEEEEGEGEEELE EEEERYYEGTMPEVCVLVLSPRFWPVASVCH-------------------MLNPTTCLPS YLRGTINHYSNFYSKSQSHSGLE-----------------------------KESPRQLQ W--TWQGRAEVQ--FG----------------------------------------DQIL HVSTVQMWLLLHLNHLKA-----VSVESLQALSELPPEVLNKAIGPLTSSRGP---LDLQ EQKN---------------IPGGVLKIRDDSEEP-----RPRRGNVWLIP-----PQTYL KAEDE---EGRNLEK---RRNLLNCLVVRILKAHGDEGLHIDQLVHLVLEAWEKGPCPPR GLVSSLGRGAACRSSDVLSCILHLLGKGTLRRHDDR-PQMLFYAV >Sus_scrofa_XM_001929214.1| . EQFARHIDQCIRGSRNGGPQGM--LAQLQQCLES-VLIFSGLEIATTFEH-YYQHYMVD- RVFAVGFSSWLEEVALDQIGPCFPNRLPQQ-IFRSLS--TSEER--QRQFHVYQLQRLDQ QLLKLEGTERKIQVGCEASGRGHTRGNGEEAELEVGVVAEAVAAIAEEAEKEEDDNEDED DNEDLYYEGAMPEMSVLVLN--GSPTGSICH-------------------PLNPRTCLPA YLRDTLNRYSNFYIKSHSYPALE-----------------------------RGPHRRLQ W--TWLGRAVLQ--FG----------------------------------------DQTL QVTTVQMWLLLHLNELQA-----VSVERLLALSGLSPDVLNWAIRPLASSRGP---LELH EPKD---------------APGGVLRIRDDSDEP-----TPRKGNVWLIP-----VPTYV KAEDE---EVRNLEK---RRNLLNCLIVRILKAHGDEGLHIDQLVCLVLKAWHKGPCPPR GLVSSLGSGSTCRSTDVLSCILHLLGKGTVRRQDDR-PQMLSYAV >Ornithorhynchus_anatinus_XM_001513758.1| . EQFAHYIDELIQAGRVGSA---ESLEQLQQSLEP-FLVLSGLELATSFEH-FYRYYLGE- RLLGPGP-CWLEEAVLDQIGLCFPNRLPQQ-MLSGLR--AAAEL--QRHFRLFRLQQFDR RLLERGQEEGDGDDGEDWGPE--------------------------------EQPEEEE EEETAEEEQSSPEMRVLVLSPRCWPVSPLCY-------------------MHEPSKYLPQ ALSGYLGRFSDFYSHGQSQPGPE-----------------------------SGPRRRLQ W--TWLGWAELV--FG---------------------------------------AQQRL LVSTLQMWILLHFNEAQE-----VTVETLLQSSGLALELLTQALGPLTSSPGP---LTLH EAEG--------------LPAEGVLRLREEATDG----TEPPGPPLRLLP-----PKAYL SMEED---QGRALEK---KRNLLSCLLVRILKTRGEGGLHVDHLVCLVLEAWKETAPPG- --------GGFCSNADVLSCILHLLGQGYMRRREEQ-PQVLVYAA >Monodelphis_domestica_XM_001364848.1| . EQFARHIDQQIQKSRVGGPRGEEVLGQLQRSLEP-MMVLSGLELATTFEH-FYQYYLAD- RLLSLGP-SWLERAVLEQIGLCFPNRLPQQ-MLSSLS--TSQEL--QHQFHLFQLEQIDQ QLLEQEEDEEHSLEARP------------------------------------QEEEEGR GERELPREEPAPEVSVLVLSPRCWPVSPLCY-------------------LYEPNKYLPP ALSTNLSRFSNFYSQSQNRPVLE-----------------------------LGPRRRLQ W--SWLGRAELL--FG----------------------------------------TQTL HVSTLQMWLLLHFNEMEE-----VALDTLLQSSDISSELLNQALQPLTSGLGP---LSLH EGQG--------------FPSGGVLRLREVEKE-------PGGEALWLLP-----PQTYL SVEED---ECRTLER---KRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPSSPK GLGSNMSGEAGCSSADVLSCILHLLGQGYVRRQEDR-PQVLAYAA >Rattus_norvegicus_XM_236927.4 . EQFARHIDQQIQGGLLGGAAGVEMLGRLQRHLEP-IMVLSGLELATTFEH-FYQYYMAD- RLLSLGS-SWLEGAVLEQIGLCFPNRLPQL-MLQSLR--TSEEL--QRGFLLFQLQQLDR QLLEQGEQEEWKLERLE------------------------------------EEDRGQE TGRELLTEDPGPAISVLVLSPRCWPVSPLCY-------------------LHQPRKHLPT EFCDALDGFSSFYSHSQHYPVLD-----------------------------MGPHRRLQ W--TWLGRAELQ--FG----------------------------------------DQTL HVSTVQMWLLLNFNQTEE-----VSVEILLRNSGLSPELLHQALLPLTSDSGP---LTLE EAQD--------------FPQGGVLRLREPRSQ-------THEEVLWLIP-----PQTYL SVEKD---EGRTLEQ---KRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPG RLGRSAAVGVACSSTDVLSCILHLLGQGYVERRDDR-PQVLMYAT >Mus_musculus_XM_355017.4 . EQFARHIDQQIHGGLLGGAAGVGMLGRLQRHLEP-IMVLSGLELATTFEH-FYQHYMAD- RLLSLGS-SWLEGAVLEQIGPCFPNRLPQL-MLQSLH--TSEEL--QHRFHLFQLQQLDR QLLEQGDQEEWRPEKVE------------------------------------EDDEGQE TGRELFT-DPGPAISVLVLSPRCWPVSPLCY-------------------LHHPRKHLQA ELCDALERFSSFYSHSQNCPVLD-----------------------------IGPHRRLQ W--TWLGRAELQ--FG----------------------------------------DQTL HVSTVQMWLLLNFNQSEE-----VSVETLLRNSDLSPELLHQALLPLTSDNGP---LTLE ETQD--------------YPQGGVLRLREPRSQ-------THEEVLWLIP-----PQTYL SVEKD---EGRTLEQ---KRNLLSCLLVRILKAHREKGLHIDQLVCLVLEAWQKGPDPPG RLGNAAAVGVACSSTDVLSCILHLLGQGYVERRDDR-PQVLMYAT >Equus_caballus_XM_001501854.2| . EQFARHIDQQIQGGLMGGAPGVEVLGRLQRHLEP-IMVLSGLELATTFEH-FYQHYMAD- RLLSLGS-RWLEGAVLEQIGLCFPNRLPQQ-MLRSLS--TSEEL--QRQFHLFQLQWFDK LLLDKEDDEEQGLE---------------------------------------EDEEEEE AEKELFIEDPSPAVSVLVLSPRCWPVSPLCY-------------------MYHPRKCLPT ELCDALDCFSNFYSQSQNHPVLD-----------------------------MGPHRRLK W--TWLGRAELH--FG----------------------------------------DQTL HVSTVQMWLLLNFNQMEE-----VSVETLLKSS-LTPELLLQALLPLTSENGP---LTLH EGPD--------------FPHRGVLRLREPRLQ-------PRGEALWLIP-----PQTYL NVEKD---EGRTLEQ---KRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPG SLGCAVAGGVPCTSTDVLSCILHLLGQGYVERRDDR-PQILMYAT >Canis_familiaris_XM_538930.2 . EQFARHIDQQIQGGLVGGATGVEMLGRLQQHLEP-IMVLSGLELATTFEH-FYQHYMAD- RLLSLGS-SWLEGAVLEQIGLCFPNRLPQQ-MLRSLS--TSEEL--QHQFHLFQLQRLDK LLLEQENEEEQGLEEEE------------------------------------EEAEEEE AEKELFIEDSSPTVSILVLSPRCWPVSPLCY-------------------LYHPRKCLPT EFCDALDRFSNFYSQSQNHPVLD-----------------------------MGPHRRLQ W--TWLGRAELR--FG----------------------------------------DQTL HVSTVQMWLLLYFNKTEE-----VSVETLLKNSDLTPELLLQALLPLTSENGP---LTLR EGQD------------LPHRVPGVLRLRTPGPQ-------HRGEALWLIP-----PQTYL NVEKD---EGRTLEQ---KRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPG SLGRTVVGGVACTSTDVLSCILHLLGQGYVERRDDR-PQILMYAT >Bos_taurus_XR_027909.2| . EQFARHIDQQIQSGLMGGTPGVEVLGRLQWHLEP-IMVLSGLELATTFEH-FYQHYMAD- RLLSLGS-SWLEGAVLEQIGLCFPNRLPQQ-MLRSLS--TSEEL--QRQFHVYQLQQLDK LFLEQEDEEEQGLEEEEVRA---------------------------------REREEEE AEKELFIEDPSPTVSVLVLSPRCWPVSPLCY-------------------LYHPRKCLPT EFCDALDRFSSFYNQSQNHPALD-----------------------------VGPHRRLQ W--TWLGRAELQ--FA----------------------------------------DQTL HVSTVQMWLLLHFNQTEE-----VSVEALLKNSGLSPELLLQALLPLTSDSGP---LTLQ EGQD--------------FPPRGVLRLREPGLQ-------PRGEALWLLP-----PQTYL NVEKD---EGRTLEQ---KRNLLSCLLVRILKAHG-KGLHIDQLVCLVLEAWHKGPNPPG SLGRAIAGGVACTSTDVLSCILHLLGQGYVERRDDW-PQILTYAT >Sus_scrofa_XM_001929351.1| . EQFARHIDQQIQGGLIGGAPGVEMLGRLQRHLEP-IMVLSGLELATTFEH-FYQHYMAD- RLLSLGS-SWLEGAVLEQIGLCFPNRLPQQ-MLRSLS--TSEEL--QRQFHLFQLQQLDK LLLEQEDEGEQGLEEEE------------------------------------DQEEEKE AEKELFIEDPSPTVSIMVLSPRCWPVSPLCY-------------------LYHPRKCLPT EFCDALDRFSNFYSQSQNHPVLD-----------------------------VGPHRRLQ W--TWLGRAELQ--FG----------------------------------------DQTL HVSTVQMWLLLNFNQTEE-----VSVEALLKKSDLSPELLLQALLPLTTDSGP---LTLQ EAQD--------------FPHGGVVQLREPGLQ-------AQGEPLWLLP-----AQMYL NVEKD---EGRTLEQ---KRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWRKGPNPPG SLGRAVAGGVACSSSDVLSCILHLLGQGYVERRDDR-PQVLMYAA >Homo_sapiens_NM_015089.2_PARC . EQFARYIDQQIQGGLIGGAPGVEMLGQLQRHLEP-IMVLSGLELATTFEH-FYQHYMAD- RLLSFGS-SWLEGAVLEQIGLCFPNRLPQL-MLQSLS--TSEEL--QRQFHLFQLQRLDK LFLEQEDEEEKRLEEEE------------------------------------EEEEEEE AEKELFIEDPSPAISILVLSPRCWPVSPLCY-------------------LYHPRKCLPT EFCDALDRFSSFYSQSQNHPVLD-----------------------------MGPHRRLQ W--TWLGRAELQ--FG----------------------------------------KQIL HVSTVQMWLLLKFNQTEE-----VSVETLLKDSDLSPELLLQALVPLTSGNGP---LTLH EGQD--------------FPHGGVLRLHEPGPQ-------RSGEALWLIP-----PQAYL NVEKD---EGRTLEQ---KRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPG TLGHTVAGGVACTSTDVLSCILHLLGQGYVKRRDDR-PQILMYAA >Pan_troglodytes_XM_001137123.1| . EQFARYIDQQIQGGLIGGAPGVDMLGQLQRHLEP-IMVLSGLELATTFEH-FYQHYMAD- RLLSFGS-SWLEGAVLEQIGLCFPNRLPQL-MLQSLS--TSEEL--QRQFHLFQLQRLDK LFLEQEDEEEKRLEEEE------------------------------------EEEEEEE AEKELFIEDPSPAISILVLSPRCWPVSPLCY-------------------LYHPRKCLPT EFCDALDRFSSFYSQSQNHPVLD-----------------------------MGPHRRLQ W--TWLGRAELQ--FG----------------------------------------NQTL HVSTVQMWLLLKFNQTEE-----VSVETLLKDSDLSPELLLQALVPLTSGNGP---LTLH EGQD--------------FPHGGVLRLHEPGPQ-------RSGEALWLIP-----PQAYL NVEKD---EGRTLEQ---KRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPG TLGHTVAGGVACTSTDVLSCILHLLGQGYVKRRDDR-PQILMYAA >Macaca_mulatta_XR_011383.1| . EQFARYIDQQIQGGLIGGAPGVEMLGQLQRHLEP-IMVLSGLELATTFEH-FYQHYMAD- RLLSFGS-SWLEGAVLEEIGLCFPNRLPQL-MLQSLS--TSEEL--QRQFHLFQLQRLDK LFLEQEDEEEKRLEEEE------------------------------------EEEEEEE AEKELFIEDPSPAISILVLSPRCWPVSPLCY-------------------LYHPRKCLPT EFCDALDCFSSFYSQSQNHPVLD-----------------------------MGPHRRLQ W--TWLGRAELQ--FG----------------------------------------NQTL HVSTVQMWLLLNFNHTEE-----VSVETLLKDSALSPELLLQALVPLTSGNGP---LTLH EGQD--------------FPHRGVLRLHEPGRQ-------RSGEALWLIP-----PQAYL NVEKD---EGRTLEQ---KRNLLSCLLVRILKAHGEKGLHIDQLVCLVLEAWQKGPNPPG TLGHTVAGGVACTSTDVLSCILHLLGQGYVKRRDDR-PQILMYAA FUNGI – FIGURE 2 >Yarrowia_lipolytica_CR382127.1 . EQLAKFSDSLLRKG------------------AKGGDSL-----------KNTADVKTLT FLLSCI-PEKDVFEVYYKRYLSK--------RLLVGRA------------LGLESESELL TILR----DEFGP--ELTESMETMLK-DVRTNSPATMAQYRDS----------------- ----EIYTKYGNFDLNVNMLSQ-NAWPQFPAST--------------------------- -------SPIRLPSQMYSQLDNFSKFLSQDP----KNTKKKVTW-QHALSSCTIRAHLNE D------------TKEFDVSLHQALVMMQFVDEKKRP---------------HMTFADLL AATGIS-----ERELTMSLHSLMTPKVK--ILIKEEGD-----------ETRYKFNWNFS ---SKLRRVKVPS----------------------------VARGADDIMLPHK-AIQDT LER-DRNMEIQAVIIRIMKAR-RTVGHAELVMEVLDKTKS-RGILEVADVKKNISKLITD DFISRQGRD------VYDYVA >Yarrowia_lipolytica_CR382128.1| . EYLSLYIDNLMKKA------------------LKGKSDE-----------EVAAILDSTV ACFNFI-TDKDRFENYYKAHLGK--------RLLNSKS------------LSDDAERQLI SRFK----MAAGG--AFTSKFEGMFK-DIATSADEMEFFRKSR---------------AS ITADSEPSSAKKVELTVALLSG-TYWPTSIAQG--------------------------- -----ANYTLIHCADAENAKEQFEQYYSK------AHSGRKLEW-VPNLGNADIRIKFKK K------------FHDVNVPNPVMPILMLFQDVGDQS----------------ISFHRIQ METGIP-----IPDLKRHLQSVSVAPKTR-LLKKVPMS------KDVNETDEFFFNENFE ---APMTKIRVL----------------------------AINATRAETDVERD-ATMVQ IDK-SRQNEIDAAIVRVMKSR-KTLNHNNLVGEVTKQLAS-RFKPPIPTIKHCIESLLER EYLRRDDND----TTLFHYEA >Yarrowia_lipolytica_CR382130.1 . ELLASYCNTLLKKT------------------TKTTEDF-----------DLEAKLENAI VIFRFL-EEKDAFQKHYTRNLAR--------RLVYNSS------------ASDDAERSMV NKLK----NECGM--EYTGKLNKMFQ-DISVSGELQEEFKERV-------------QQKR QDAAASGGEANLVDFSPTIIAE-GCWPLPSVKD--------------------------- --------GFRLPNDLTKTYEAFTQYYQA------KHQGRKLKW-LWNFTKGDVKIHTKG SK----------IGYSVTASIYQIAILLAYNDADV------------------LSVADLQ EITGLS-----NTYLHGSLHLILKSKF---LLVEGVSGDPKD--VELTPETRIVFNQDFK ---SKKIRININ------------------------------GVIKTEAKAEAE-ETKKA IEE-DRKWFLQATIVRVMKAR-KTLKHTALVQETIVQSKK-RFHPKIGEIKKVIDDLIER EYLTRIEQD------KYEYAA >Ajellomyces_capsulatus_ABRJ01000388.1| . ELLARYTDSLLKKG------------------VKSPEES-----------ELEEMLVQIM TVFKYI-EDKDVFQKFYSRMLAK--------RLVHVSS------------VSDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DIQISKDLNASYRDWQ----------------- EKVLDDEDRKKLLDPHFQILGT-GFWPLTPPTT--------------------------- --------QFIPPQEIVKTTERFKNFYFD------KHSGRKLTW-LWNLCKGEIRANYIK N---------TKVPYTFQVSTYQMGILLLFNESDT------------------LSFSDIE KGTALA-----PEVLEPNLGILVKAK----VVIPSPED------GKPCPGTSYALNYNFK ---AKKIKINLN------------------------------ISVKSEQKHETD-DTHKT IDE-DRKLLLQSAIVRIMKSR-KKLKHVQLVQEVIQQVKA-RFPPKVPDIKKNIEALMEK EYIERLDGD------DLAY-- >Ajellomyces_capsulatus_XM_001538245.1| . EYLSLFFDENLKKG------------------IRGKTEE-----------EIDTLLENGI TLLRYI-RDKDCFESYYKKHLSR--------RLLMKRS------------ASTEAERQMI EKMK----MEVGN--TFTQKLEAMFK-DMELSSGLTSKYANYV----------------- --SQQGDPNLKRIDLEISVLTS-TMWPMEMVTS--------------------------S NKNGTPSAHCNYPKHIEQLKQSFEQFYLG------QHNGRKLSW-QSGMGTADIRATFPR PNGK-------VARHDLNVSTYAMVILLLFNDLPADKS---------------LTFEEIQ ARTNIP-----TSELSRNLQSLAVVRKTQ-VLMKEPMS------KDVKPTDRFFFNEKFQ ---SPYTKIKIG--------------------------VVSSAGNKVENKDERQ-ETERK MSE-ERGGSIEAAIVRIMKQR-KTLSHSQLMAEVISQLAS-RFNPEVNMVKKRIESLIDR EYIDRIPDSD---PPAYVYHA >Ajellomyces_capsulatus_XM_001542335.1| . EMIAKYVDMLLRGGVKAIQ-------------GLAEESKSGSTALVDEDAEINQKLDQVL DLFRFV-HGKAVFEAFYKNDLAR--------RLLMGRS------------ASDEAEKSML ARLR----SECGS--NFTHNLESMFK-DMDLARDEMASYNALL----------------- ----GPNRDRSNMDLNVNVISA-AAWPSYPDVQ--------------------------- ---------LKIPKVISSAMDSFEQFYNN------KYNGRKLHW-KHSLAHCQLKAKFPN G------------NKEIVVSSFQAVVLLLFNDVEDDT---------------TLSYPEIK EATGLS-----DIELKRTLQSLACAKYR--VLTKRPKG------RDVNDDDTFSFNSNFS ---DPKMRIKIN------------------------------QIQLKETKQENK-TTHER VAA-DRHYETQAAIVRIMKAR-KVITHAELLVEVINKTKS-RGVLEPAGIKTNIEKLIEK DYIEREEGN------KYRYL- >Arthroderma_gypseum_ABQE01000301.1| . EYLSLFFDENLRKG------------------IKGKTEE-----------EVDTLIENGI TLLRYI-RDKDLFETYYKKHLSR--------RLLMKRS------------ASMDAERQMI AKMK----MEVGN--TFTQRLESMFK-DMAVSTDLTTNYRDYI----------------- --AQQGDPDIKRIELEMSVLTS-TMWPMEIMSS--------------------------Y SRDGQVQLPCIFPKNVESLKQSFERFYLD------KHSGRKLWW-LPGMGTADIRATFTR PNGK-------VERHDLNVSTYAMVILLLFNDMPSGES---------------LTFEEIQ EKTRIP-----TNELIRNLQSLAVAPKTR-VLRKEPMS------KGVQPSDKFSFNEQFT ---SKFTRLKIG--------------------------VVSAGGNKVENKEERT-DTEKK TSE-ERGNTIEAAIVRIMKTT-ENIGSFAVITEAISQLAA-RFTPDVNMVKKRIESLIDR EYLERITDSD---PPAYSYVA >Ashbya_gossypii_AE016819.3 . EFMALSLDILVKRF--------------------------------------MEYVKVLV ESKAGF-SKRFVESSFYEKTMSEME------TILLAMK----QMRLFSTFINFYYERYWF RRLV----L------YAREYKKCLDR-DISLIEDRIEPYAENG---SVVASAMLEAVKNI KKYSTSSTANAIDAISI-VLPR-SSVPNIFLEH--------------------------- -----NITVKTLPDDLCPITPSLERQSSV------MPPSTVVEE-QCSLHHLEIETPFLL KD---------NRNLTLDVTMVQACILDMFNNQDS------------------VSLDDVS NKYGIQ-----VAELKTAMDSFVSIN----MMKCEGGQ--------YTIDPAFDPNIGVT --ASGKRRVPYT----------------------------------SARHPKTS--EKRD SAW--RVEIIRAALVRTLKYEQTWLTFDSLKNAVSAQIDG----FSVGEFKAALDKC--K DYYAERDGK-------YIFVF >Ashbya_gossypii_AE016819.3| . DYLVMSIDSVLRSN--------------------TTLEE-----------EQQELLERCI SFFILM-RDKDLFELSYRQQLSK--------RLLQRKS-------------PFHLEQWMV GKMT----QEVGI--HYTSNLEGMLR-DVKLSQGYSAKFSAPA----------------- --------AAAGAAYQMDVLTP-TFWPFQQVET--------------------------- -----LAQDITLSDELAAARSSYEGLYVS------QHSGRRLKW-EYNLGSVRIGHQFGQ S------------YHELTMWTYGATIFLLFRDYAE------------------LTTEKIQ DLTAIP-----DAELQRQLISLAVAPRTR-ILTKTPPS------RTIAPSDHFAVNTAFT AP-TTKVRVATV----------------------------------VVKSEQAA-ALPDV LAA-SRVQAISAAVVRQLKTE-RTMAHTELQDAAVRALQR-HFAVSTSMFKRAIQSLLEK EYIQRDAHS----PDRYHYLA >Ashbya_gossypii_NM_209555.1| . EMLAKYSDQLLKKN-------------------KNGTDG-----------DKDMSVDDIM TIFKFL-TDKDAFEYHYRKNLAK--------RLIHGTS------------TSEENEEMVI QRLQ----SENSM--EYTGRITKMFQ-DVRLSKQLGQEFDSQI----------------- -KSEPDYSKERYPEFQPFVLAE-TMWPFPYQEV--------------------------- --------EFKLPQELVAEHQKLVDLYVK------KHSGRVLKW-LWPLSRSELRADIGR PGR---------PPFHFTVTLFQMAILLMFNENDT------------------LSFEQIQ EGTNLT-----TQHIILSMLPFIKMK----LLHQSPPG----LESMGLLGTQYKLNLPYK ---LAKSKVNFAAGVKGDV-SLSGS-------------------GK-ADNMDSD-NINKE LNK-ERQLFLEACIVRIMKAK-RVVSHATLVNECIAESHQ-RFNAKVSLIKKAIDNLISK EYLQRSRDG-----ESYEYLA >Aspergillus_clavatus_NZ_AAKD03000005.1| . EFLSLFFDENLKKG------------------IKGKTES-----------EVDALLDNGI TLLRYI-KDKDLFETYYKKHLSR--------RLLMKRS------------ASMDAERQMI SKMK----MEVGN--QFTQRLEAMFK-DMTISEDLSASYKDHI----------------- --RKTGDPDQKRVDLEINVLTS-TMWPMEIMSN--------------------------P RD-GDVQLPCLFPKEVEGVRQSFEQFYLS------KHNGRKLSW-QPNMGTADIRATFQR SNGK-------VQRHELNVSTYAMVILLLFNDVPTGES---------------LTFEGIQ ERTRIP-----EHDLIRNLQSLAVAPKTR-VLKKEPMS------KDVKPTDKFFFNNDFQ ---SQFMKVRIG--------------------------VVSGGANKVENQDQRK-ETEGK MNE-ERGASVEAAVVRIMKQR-KTLVHSSLMSEVLSQLSS-RFVPDVNMVKKRIESLIDR EYLERVAEE----PPTYGYIA >Aspergillus_clavatus_XM_001268961.1| . ELLARYTDSLLKKG------------------SKAAEES-----------ELEEMLVQIM TVFKYI-EDKDVFQKFYSKMLAK--------RLVHVSS------------VSDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DIQISKDLNASYKDWQ----------------- EKVLDDDDRKKQVDAHFQILGT-GFWPLNPPTT--------------------------- --------GFSAPPEIVKTYERFQSFYYD------KHNGRKLTW-LWQLCKGEVKANYIK N---------TKVPYTFQVSTFQMGILVLFNEQDT------------------LSYSDIQ NATSLA-----PEILDPNLAILLKAK----VLLPSPEG------AKPGPGASFSLNYNFK ---NKKIKVNLN------------------------------IQIKSEQKVETD-DTHKT IEE-DRKLLLQSAIVRIMKSR-KKMKHVQLVQEVIQQVKS-RFPPKVQDIKKNIEALMEK DYIERLDGD------EIAY-- >Aspergillus_clavatus_XM_001274555.1| . ------------------------------------------------DAEINRQLDQVL DLFRFV-NGKAVFEAFYKNDLAR--------RLLMGRS------------ASDDAEKSML ARLK----TECGS--TFTHNLESMFK-DMEVARDEMAAYSSIQ----------------- ----RERKKRLPVDLNVSVLSA-SAWPSYPDVQ--------------------------- ---------VRIPAVIATAIDDFENFYHN------KYNGRKLTW-KHQLAHCQLRAWFGG K------------SKELVVSSFQAIVLLLFNDVEESK---------------RLTYSEIQ DATKLS-----DPELQRTLQSLACAKYR--VLTKTPKG------RDVNKTDEFAYNAEFN ---DPKMRIKIN------------------------------QIQLKETKEENK-KTHER VAA-DRHLETQAAIVRIMKSR-KRSTHAELVAEVIKATRS-RGVLEVADIKSNIEKLIEK DYIERD-DN------VYQYVA >Aspergillus_fumigatus_BX649606.1 . ELLARYTDSLLKKG------------------SKAAEES-----------ELEEMLVQIM TVFKYI-EDKDVFQKFYSKMLAK--------RLVHVSS------------VSDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DIQISKDLNSNYKDWQ----------------- EKVLDEDDRKKQVDAHFQILGT-GFWPLNPPTT--------------------------- --------GFSAPPEIVKTYERFQSFYYD------KHNGRKLTW-LWQLCKGEVKANYIK N---------TKVPYTFQVSTFQMGILLLFNENDT------------------LTYSDIQ KATSLA-----PEILDPNLAILLKAK----VLLPSPEG------AKPEPGTSFSLNYNFK ---NKKIKVNLN------------------------------IQIKSEQKVESD-DTHKT IEE-DRKLLLQSAIVRIMKSR-KKMKHVQLVQEVIQQVKS-RFPPKVQDIKKNIEALMEK DYIERLDGD------EIAYIA >Aspergillus_fumigatus_XM_745618.1| . EFLSLFFDENLKKG------------------IKGKTES-----------EVDSLLDNGI TLLRYI-KDKDLFETYYKKHLSR--------RLLMKRS------------ASMDAERQMI SKMK----MEVGN--QFTQRLEAMFK-DMTISEDLSASYKEHI----------------- --RKSGDPDQKRVDLEINVLTS-TMWPMEIMSN--------------------------P KD-GEVQLPCILPKEVESVKQSFEQFYLN------KHNGRKLSW-QPSMGTADIRATFQR SSGK-------VQRHELNVSTYAMIILLLFNDVPTGES---------------LTFEEIQ ERTRIP-----QHDLIRNLQSLAVAPKTR-VLKKEPMS------KDVKPTDKFFFNNEFQ ---SQFMKVRIG--------------------------VVSGGANKVENQDQRK-ETENK MNE-ERGASIEAAIVRIMKQR-KTLVHSSLMSEVLGQLSA-RFVPDVNMVKKRIESLIDR EYLERVAED----PPTYGYIA >Aspergillus_fumigatus_XM_748292.1| . EMIAKYVDRLLKGGWKLAS-------------GRNMADVP----LADEDAEINRQLDQVL DLFRFV-NGKAVFEAFYKNDLAR--------RLLMGRS------------ASDDAEKSML ARLK----TECGS--TFTHNLESMFK-DMDVARDEMAAYASIQ----------------- ----RERRKPLPIDLNVSVLSA-SAWPSYPDVQ--------------------------- ---------VRIPPVVAEAIDDFEKFYYN------KYNGRKLSW-KHQLAHCQLRANFSH G------------QKELVVSSFQAIVLLLFNDVPEGG---------------SLSYAQLQ EGTKLS-----DQELQRTLQSLACAKYR--VLTKKPKG------RDVNPTDEFSFNASFT ---DPKFRIKIN------------------------------QIQLKETKEENK-KTHER VAA-DRHLETQAAIVRIMKSR-KQISHAELVAEVIKATRS-RGVLDVAEIKNNIEKLIEK DYMERDTETS---PNMYKYVA >Aspergillus_nidulans_NW_101305.1| . EFLSLFFDENLKKG------------------VKGKTDN-----------EVDALLENGI TLLRYI-KDKDRFEAYYKKHLSR--------RLLMKRS------------MSMDAERQMI SKMK----MEVGN--QFTQRLEAMFR-DMTISEDLTASYKQFV----------------- --REQGDPDKKRFELDINVLTS-TMWPMEIMSS--------------------------S RD-GQVELPCIIPKEVETVKQSFEKFYLD------KHSGRKLSW-QPSMGTADIKATFHR SNGK-------VQRHELNVSTYAMFILLLFNDIPIGES---------------LTFEEIQ ARTRIP-----DNDLIRNLQSLAVAPKTR-VLKKVPMS------RDVKPTDKFYFNNDFQ ---SPFMKVRIG--------------------------VVSGGANKVESQDQRK-ETEEK MNN-ERGGSIEAAIVRIMKQR-KTLIHSNLISEVLSQLSA-RFVPDVNMVKRRIESLIDR EYLERVSED----PPTYGYVA >Aspergillus_nidulans_XM_652549.1| . EMIAKYVDRLLRGGWRLAP-------------TREAENMP----LADEDAEINRQLDQVL DLFRFV-HGKAVFEAFYKNDLAR--------RLLMGRS------------ASDDAEKSML ARLK----TECGS--SFTHNLESMFK-DMEVARDEMSAYNSIK----------------- ----RERQTPLPVDLHVSVLSA-SAWPTYPDVQ--------------------------- ---------VRIPPEIATAISDFEKFYDT------KYNGRKLAW-KHQLAHCQLRARFPN G------------NKELVVSSFQAIVLLLFNELPEGG---------------TLNYRQIQ EATTLS-----DQELTRTLQSLACAKYR--VLSKKPKG------RDVSPTDEFSYNASFT ---DPKFRIKIN------------------------------QIQLKETKEENK-TTHER VAA-DRHYETQAAIVRIMKSR-KTITHAELVAEVIKATRS-RGVLEPADIKKNIEKLIEK DYMEREDGN------RYQYVA >Aspergillus_nidulans_XM_653531.1 . ELLAKYTDSLLKRG------------------SKAAEES-----------ELEEMLVQIM TVFKYI-EDKDVFQKFYSKMLAK--------RLVHVSS------------VSDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DIQISKDLNSSYKDWL----------------E KSFLDDDDRKKLVDSHFQILGT-GFWPLTAPST--------------------------- --------SFLAPPEIVKTSERFQKFYCD------KHNGRKLTW-LWQLCKGELKANYIK N---------TKVPYTFLVSTYQMGILLLFNESDT------------------LTYSDIQ KATTLT-----PEILDPNLSIFLKAK----VLNISPEG------SKPGPDSTFSLNYNFK ---NKKIKVNLN------------------------------IQIRSEQKVETD-DTHKT IEE-DRKLLLQSAIVRIMKSR-KKMKHVQLVQEVIHQVKS-RFPPQVPDIKKNIEALMEK DYIERLDGD------EIAYIA >Aspergillus_niger_NW_001594334.1| . EMIAKYVDRLLKGGWKLAP-------------ARKAEDMP----LADEDAEIDRQLDQVL DLFRFV-HGKAVFEAFYKNDLAR--------RLLMGRS------------ASDDAEKSML ARLK----TECGS--SFTHNLESMFK-DMDVARDEMSAYSSIQ----------------- ----RERRDRLPVDLNVSVLSA-SAWPTYPDVQ--------------------------- ---------VRIPPEIATAVDDFEKFYNT------KYNGRKLNW-KHQLAHCQLRARFPK G------------DKELVVSSFQAIVLLLFNDIPEGG---------------SLGYAQIQ EATMLA-----DQELKRTLQSLACAKYR--VLSKKPKG------RDVNTTDEFSYNAAFT ---DPKMRIKIN------------------------------QIQLKETKEENK-TTHER VAA-DRHYETQAAIVRIMKSR-KTITHAELVAEVIKATRS-RGVLEPADIKKNIERLIEK DYMEREEGN------RYQYVA >Aspergillus_niger_XM_001392667.1| . ELLARYTDSLLKRG------------------SKAAEES-----------ELEEMLVQIM TVFKYI-EDKDVFQKFYSKMLAK--------RLVHVSS------------VSDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DIQISKDLNASYRDWQ----------------- EKILDDDDRRKLVDSHFQILGT-GFWPLSAPST--------------------------- --------DFLAPPEIVKTAERFQSFYFD------KHNGRKLTW-LWQLCKGEIKTNYIK N---------TKVPYTFQVSTFQMGILLLFNEHDT------------------LSYEDIQ KATSLA-----PEILDPNLSIFLKAK----VLTINPEG------SKPEPGTSFSLNYNFK ---NKKIKVNLN------------------------------IQIKSEQKVESD-DTHKT IEE-DRKLLLQSAIVRIMKSR-KKMKHVQLVQEVIQQVKS-RFPPKVPDIKKNIEALMEK DYIERLDGD------EIAY-- >Aspergillus_niger_XM_001394154.1| . EYLSLFFDENLKKG------------------IKGKTDS-----------EIDTLLDNGI TLLRYI-KDKDMFEAYYKKHLSR--------RLLMKRS------------VSMDAERQMI SKMK----MEVGN--QFTQRLESMFK-DMTISEDLTSSYKEHM----------------- --RQSSDPDQRRIELDINVLTS-TMWPMEIMSN--------------------------A RN-DEVQLPPILPKEVDSVKQSFEQFYLG------KHNGRKLSW-QASMGTADIRATFQR ANGK-------VQRHELNVSTYAMIILLLFNDVPAGES---------------LTYTDIQ ARTRIP-----DHDLIRNLQSLAVAPKTR-VLKKDPMS------KDVKPTDKFVFNNEFQ ---SPFMKVRIG--------------------------VVSGSANKVENQDQRK-ETEKK MSE-ERGASIEAAIVRIMKQR-KTLIHSQLMTEVLSQLSA-RFVPDVNMIKKRIESLIDR EYLERVEED----PPTYGYVA >Aspergillus_oryzae_XM_001727536.1| . ELLAKYTDSLLKKG------------------SKAAEES-----------ELEEMLVQIM TVFKYI-EDKDVFQKFYSKMLAK--------RLVHVSS------------VSDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DIQISKDLNASYKDWQ----------------- DKVLDDDDRRKLVDAHFQILGT-GFWPLQAPST--------------------------- --------DFLAPPEIVKTAERFQNFYFD------KHNGRKLTW-LWQLCKGEIKTNYIK N---------TKVPYTFQVSTFQMGILLLFNETDT------------------LTYEDIQ KATTLA-----PEILEPNLGIFLKAK----VLTINPEG------SKPEPGTSFTLNYNFR ---HKKVKVNLN------------------------------IQIKSEQKVESD-DTHKT IEE-DRKLLLQSAIVRIMKSR-KKMKHVQLVQEVIQQVKS-RFPPRVPDIKKNIEALMEK DYIERLDGD------EIAY-- >Aspergillus_oryzae_XM_001819284.1| . EYLSLFFDENLKKG------------------IKGKTET-----------EVDALLDNGI TLLRYV-KDKDLFEAYYKKHLSR--------RLLMKRS------------VSMDAERQMI SKMK----MEVGN--QFTQRLESMFK-DMTVSEDLTASYKEHI----------------- --RGAGDPDQKPVDLEINVLTS-TMWPMEAMSS--------------------------I KG-DEVQLPCIFPKEIDHLRQSFEQFYLS------KHNGRKLSW-QASMGTADIRATFHR SNGK-------VQRHELNVSTYAMVILLLFNDVPQGEP---------------LTYEEIQ ARTRIP-----DHDLIRNLQSLAVAPKTR-VLKKDPMS------KDVKPADRFVFNNDFQ ---SPFMKVRIG--------------------------VVSGSANKVENQDQRK-ETEKR MND-ERGASIEAAVVRIMKQR-KTLVHSKLMSEVLSQLSA-RFVPDVNMIKRRIESLIDR EYLERVGED----PPTYGYVA >Aspergillus_oryzae_XM_001824058.1| . EMIAKYVDRLLKGGWKLPP-------------GRKAEDVP----LADEDAEINRQLDQVL DLFRFV-HGKAVFEAFYKNDLAR--------RLLMGRS------------ASDDAEKSML ARLK----TECGS--SFTHNLESMFK-DMDVARDEMAAYNSIQ----------------- ----RERKHRLPVDLNVSVLSA-AAWPSYPDVQ--------------------------- ---------VRIPPEIATAVSDFEKFYYS------KYNGRKLNW-KHQLAHCQLRARFPK G------------DKELVVSSFQAIVLLLFNDISEKG---------------TLSYLQIQ EATKLS-----DQELKRTLQSLACAKYR--VLAKKPKG------REVNTTDEFSYNEGFS ---DVKMRIKIN------------------------------QIQLKETKEENK-TTHER VAA-DRHYETQAAIVRIMKSR-KTITHPELVAEVIKATRS-RGVLEPADIKKNIEKLIEK DYMEREEGN------RYQYVA >Aspergillus_terreus_XM_001210577.1| . ELLAKYTDSLLKKG------------------SKAAEES-----------ELEEMLVQIM TVFKYI-EDKDVFQKFYSKMLAK--------RLVHVSS------------VSDDAETSMI SKLK----EASGF--EYTNKLQRMFQ-DIQISKDLNASYKDWQ----------------- EKVLDDDDRKKLVDTNFQILGT-GFWPLQAPST--------------------------- --------DFLAPPEIVKTAERFQNFYFD------KHNGRKLTW-LWQLCKGEIKANYIK N---------TKVPYTFQVSTFQMGILLLFNETDT------------------LEYSDIQ KATSLA-----PEILEPNLGILLKAK----VLTISPEG------SKPGPGTSFSLNYNFK ---NKKIKVNLN------------------------------IQIKSEQKVESD-ETHKT IEE-DRKLLLQSAIVRIMKSR-KKMKHVQLVQEVIQQVKS-RFPPKVPDIKKNIELLMEK DYIERLDGD------EIAY-- >Aspergillus_terreus_XM_001211178.1| . EMIAKYVDRLLKGGWKLPP-------------GRNADDVP----LADEDAEINRQLDQVL DLFRFV-HGKAVFEAFYKNDLAR--------RLLMGRS------------ASDDAEKSML SRLK----TECGS--SFTHNLESMFK-DMDVARDEMVAYNSLQ----------------- ----RERRHRLPVDLNVSVLSS-ASWPTYPDVQ--------------------------- ---------VRIPPEIATAVDDFEKFYYN------KYQGRKLNW-KHQLAHCQLRARFPK G------------DKELVVSSFQAIVLLLFNEVPEGG---------------SLSYAQIQ EATSLS-----DKELKRTLQSLACAKYR--VLSKKPKG------RDVNPTDEFSYNAGFS ---DAKMRIKIN------------------------------QIQLKETKEENK-TTHER VAA-DRHYETQAAIVRIMKSR-KTITHPELVAEVIKATRS-RGVLEPADIKKNIEKLIEK DYMEREEGN------RYQYVA >Aspergillus_terreus_XM_001215013.1| . EHLSLFFDENLKKG------------------IKGKTDD-----------EVDALLENGI TLLRYI-KDKDLFEAYYKKHLSR--------RLLMKRS------------VSMDAERQMI SKMK----MEVGN--QFTQRLESMFK-DMTISEDLTTSYKKHI----------------- --QQSGDPDQKRVDLDINVLTS-TMWPMEIMSN--------------------------T RD-DQVQLSCIFPKEIDSVRQSFEKFYLD------KHSGRKLSW-QASMGTADIRATFHR SNGK-------VQRHELNVSTYAMVILMLFNDVESGES---------------LTFEEIL ERTRIP-----DHDLKRNLQSLAVAPKTR-VLKKDPMS------KDVNPGDKFFFNNEFQ ---SPFMKVRIG--------------------------VVSGGASKVENQDQRK-ETEKR MND-ERGASIEAAVVRIMKQR-KKLVHSQLMTEVLSQLSS-RFSPDVNMIKKRIESLIDR EYLERVHDD----PPTYGYLA >Blumeria_graminis_ABSB01005395.1| . ---------------------------------------------GDDDAELDRQLEQAL ELFRFI-EGKDIFEAFYKKDFAR--------RLLMARS------------ACQDAERNML AKLK----LECGC--TFTQNLEQMFK-DMETSRDEMTAYRKSL----------------- -----KKPKKETIDLQVNILYE-AAWPSYPDVV--------------------------- ---------VNLPPEVAVHVEKFDHFYTQ------KHSGRRLTW-KNSLAHCVIKAQFNK G------------AKELLVSAFQAIVLVLFNNVKPSD---------------PLSYSTIQ QVTGLV-----DLELQRTLQSLACAKFR--VLTKHPKG------REVNNTDTFTVNTNFT ---DAKYKVKIN------------------------------QIQLKETKEDNV-ETHEK VFR-DRQYETQAAIVRIMKSH-KTMTHSNLISEVIEQTKG-RGAVEISEIKSNIDS---- --------------------- >Botryotinia_fuckeliana_NZ_AAID01001478.1| . EYVSLFIDDNLKRG------------------IKGKTEV-----------EIDEVLDKAT TLLRYI-QDKDMFERYYKKHLAK--------RLLLNKS------------ESTDVEKQMI SRMK----LEIGN--SFTTKLEGMFK-DVTMSEELTQNYRNHI----------------- --NNLGDKDHKQIELSAIVLST-NCWPTEIIGG------------------------IPS SDEG-PRQYCNWPPEMQKLQDSFKAFYLK------DRNGRMLTW-LGNLGNADIRCYFPA IPGETGPKSR-ERKYELNVNTYGMIILMLFNDLPDGAT---------------LSYEEIQ ERLNIS-----DKELPRALMQLSGPPKSR-VLLKKPGKPN----ELPTIGDVFTFNSSFV ---SKSHKIKVQ--------------------------AMGGQTSKVEGAEERR-LTEER NDE-HRGNVMDTVIVRIMKAR-KEFPHQQLVTEVISQLAQ-RFQPNINMMKRRIESLIER EYLERIEDAK---VPTY---- >Botryotinia_fuckeliana_XM_001554582.1| . ---------------------------------------------GDEDAELDRQLEQGL ELFRFI-EGKDVFEAFYKKDLAR--------RLLMARS------------ASQDAERNML AKLR----GECGN--SFTHNLEQMFK-DQDISRDEMISYKQSL----------------- -----SNTSKTTLDLQVSVLSS-AAWPTYPDIE--------------------------- ---------VNLPAEVARHIEKYDRHYKH------KHSGRRLTW-KHSLAHSVVKATFKK S------------VKELLVSGFQAIVLVLFNDLEDGG---------------HLSYKDIS KATGLV-----DVELKRTLQSLACAKIR--PLAKYPKG------RDINDTDTFTINLNFS ---DPKYRIKIN------------------------------QIQLKETKEENK-ETHER VIQ-DRSFETQAAIVRIMKSR-KTMTHQNLVAEVINQTKG-RGAVEPAEIKKHIEKLIEK DYIEREDGG------HYT--- >Candida_albicans_AAFO01000007.1| . YQLCKYCDNFFKGK----------------------SSS----------LLFPEFEKNVL IIFKSI-NNKQDFINFYKKDLSK--------RLLLLNQK-----------FKFENEQKFI NSLI----KVVGE-NDDVLSLTVMFK-DLTDSKDIYKSLITVP----------------- --TANYTLLNNSFEFNPLILEK-KQWPNIPNNE--------------------------- -----DLHEFKLPVVLQDILTEMTNQYQTLDV---KYKNRQLDWTNYKLHQITMSAQFDQ G------------EKEITGNLLQIVLLLLFTAEDDNG----------------YTIEQLS SMTGINN----TQFLTKIVNSITNDKYA--ILRYDGNR--------------YYYNSSFK ---DKSTRIKLPMIKELS---------------RSEQQQQQQQEKQVKGMNDID-LVEST VQA-NRDDEIKSCVVKIMKQE-RQLTIIELLNKSISVLQN-RRPVTMTNLKTIIENLIEL EYLKRDDHN----KNIIIYIP >Candida_albicans_XM_713561.1| . ELLSVYMDYFIKQLTK--GSSS-------NKDISLKSGD-----------QTEDLISNSI QFLRFI-KDKDAFEANYANHFAK--------RFLNSKT----GNS---PSSNKDIEEIIL AKLS----EEMGT--SSLDKVIKMNR-DVRLSKDTTNDWKRYL----------------- ---NKQSKSTDLVEMELKICNV-TDWPKSMTKDYKWFSRTE------------------- ----NEETPFKWPRQLRNTIKQFDEFWSNGK----KNDNKSLYW-SPKFGSMDLRITYPS R------------TYEINLSTFAAIIMLLFAPQLTNADGST---VLAFDEMKELTYEEIL ELTGIP-----EPELKRHLQSIAVAPKLR-LLVKVPMS------KDVNKNDVFKLNAKFK SP-SVKVKVLTVSASSSSSASSS----------SSSSKNTNKSVAKTEQEEELE-EVNAN IME-GRKIEVNAAIVRILKSR-QSIKHNDLIEELLKQLSN-RFQPLIILIKQRIEDLIDK EYLKRDTDD----RNLYHYIA >Candida_albicans_XM_716539.1| . ELLARYADGFLKSN------------------SK----------------DNEMNADNLM IVFKFI-AERDSFEEHYRRLLAK--------RLVNGTS------------KSEEMEESVI HRLQ----EENSI--EYTSKMTKMFT-DIKASDDLKIKFKDGM----------------- ---------NVLFDFSPMVLAR-STWPFHSSQD--------------------------- ------YNDLKLAPELKVTIDSFKAMYLQ------QGKGKQIEW-LWNHGRAELKAHLTK GKG--------GKPFNFIVSQIQLMVLLAYNYSKT------------------YTLDDLV KIVGIK-----KELLQNHVTPFVKYK----LLKEE--------------GDQLVIVDHYP ---SKKNKVSFIGAITK------------------------------TKEEDVE-EITKE VQQ-SRTIFLEASIVRIMKLK-KLMAPNNLLNEVVVQAGN-RFNAKNIDVKRAIDSLIDK EYLKRNGDD-------YEYIS >Candida_glabrata_CR380952.1| . EFVTIYLDSCLKLS------------------IEKQKYK-----------QVKQDLDAAV KLFKLL-QEKDIFSQYYQQQLSK--------RLLQQKS-------------SLDLERWLI TQIK----SEMGS--LFTSKLEGMLR-DVNSSIELYKTFQNTT----------------- ------KEAVAGFMFKPQILTP-TSWPFQAPDR--------------------------- -----VDPNFKLPETLQGIQDSFETFYTN------KYNQRILKW-SHHLSSIEVGYQFAK T------------YHEIHLPIYAASIFFLFENHDS------------------LTKDEIQ DMTGLP-----DVELDKLLLSMTTAPRSK-ILVKSPPS------KIINSTDTFAINEDFT AP-TTKVKLQMI--------------------------IGVVQPNNGTGEPNKA-SIMDN VER-ERQEVTNAAIVRLMKSE-RHLQFSELQEKTAVQLAQ-RFTLSLATFKACIETLIEK EYIQRDVDD----HEFLHYIT >Candida_glabrata_CR380956.2 . EMLAKYSDQLLKKS------------------TKPEVAN-----------DM--SDDDII TIFKFI-TDKDAFESHYRRLFAK--------RLIHGTS------------TSSDDEESII KRLQ----TENSM--EYTGKITKMFQ-DVRLSKMLESDFDVMI----------------- -KSQSDYSREKFPELQPFVLAE-NMWPFSYQEV--------------------------- --------DFRLPEELVASHKKLESMYIG------KHNGRILKW-LWPLCRGELKADIGK PGR---------VPFVFTVTLFQMSILLLFNDKDV------------------LTFEEIQ EGTNLN-----IQNIASSMVPFIKFK----LVQQLPPG----LDNLVKGDTQFKLNRPYK ---AVKTQINFAAGVKNDILGTISKS--------SNSVSNGVSGISDEKLSESE-KIEKE LNA-ERQMFLEACIVRIMKTK-RNLPHSTLVNECIAQSHQ-RFKAKISMIKRAIDSLIQK GYLQRGEDG-----ESYTYLA >Candida_parapsilosis_CABE01000008.1| . DLLSIYMDYHIKQLSK--GST--------GKELSTQSGD-----------QTEILMNKSV QLLRFI-KDKDAFEAYYANHFAK--------RFLNAKGSTI------GALKSGDIEEMLL SKLC----EELGS--SSLDKVIKMNK-DIKISRDTTRDWKNHL----------------- ---SKVEQLLSLIELDLKICNV-SVWPNSLTKDYKSSKPDG------------------- -----EEFAFKWPRQLRETIREFEEFWLSGK----KNDNKSLYW-SPKFGSIDLKITYPS K------------TYEINLSVYSAIIMLLFAPGLSLDGEP----NLAFEETKEYSYRDIV ELTGIP-----SLELKRHLQSIAVAPKLR-LLIKIPMS------KDIKEDDVFRLNDKFK SP-TVKVKVPTVSLASS---------------------TASGKNKKSKEQEETD-AVNAN ISE-GRRIEINAAIVRILKSR-RTVKHNELIEGLVKQLSN-RFQPLVVLIKQQIEDLIDK EYLERDAND----RNVYHYIA >Candida_tropicalis_AAFN01000066.1| . -----YMDYYIKQLTKS-GSS-----------GILKSGD-----------QTEELINTSI QFLKYI-KNKDAFEVHYANHFAK--------RFLNSKN-----------SSSKDIEEIIL GSLS----EELGV--SSLDKVIKMNR-DIRLSRDTTNDWKKYT----------------- ------RGRDDIIELELKICNV-TNWPKAMTKNYK------------------------- -----EDVLLKWPNALQHSLIAFEEYYAG------KNANKKLSW-S-TFGSMLIKASLPT G------------NFMIDVGVVAGNILLQFNDHEK------------------LKFGEIK ELVYGEDNKVEDSELKRHIKSLLISK----LL--------------VYKNDYFLLSENKV K--SRLLKVKTVASS-----------------------------KKSEMDEQES-ELEQE VRK-GMKIKTEASIVRIMKSY-KTISHQQLIEQLIQQV---SFSPTMLLIKECIEDLIEK EYLKRDGLD----RSLYNYIA >Chaetomium_globosum_NZ_AAFU01000778.1| . ELLAKYTDVLLRKS------------------STGVEDA-----------ELETRLVQIM TVFKYI-EDKDVFQKFYSRMLAR--------RLVHSNS------------SSDDAETSMI NKLK----EACGF--EYTNKLQRMFL-DMQISKDLNSGFREHV----------------- -----QTLGTKGLDSSYSILGT-GFWPLTAPGT--------------------------- --------NFDPPEEVSADCERFSRYYKN------KHEGRKLTW-LWQLCKGEVKANYVK N---------AKMPYTFQVSIYQMAILLLFNEKDK------------------NTYEELA SATQLN-----NEALDPALGILLKAK----VLNLEPGSGGG---SKVGPGSSFTLNYEFK ---NKKYRVNLN------------------------------VGMKSETKQEEA-ETNKT IEE-DRKLLLQSAIVRIMKAR-KHMKHQQLVSEAINQIRA-RFVPKVSDIKKCIEILLDK EYLERLEED------EIGY-- >Chaetomium_globosum_XM_001229747.1| . ---------------------------------------------GDEDSELDRQLDYAL ELFRFI-EGKDVFEAFYKKDLAR--------RLLLGRS------------ASQDAERSML AKLK----VECGS--GFTHNLEQMFK-DQALAKEEMTSYKQWF----------------- ---RGTGKNDGGVDLTVNILSA-AAWPTFPEVK--------------------------- ---------VLLPKEVLEQVNTFDSYYKS------KHTGRRLTW-MHNMAHCVVGARFNR G------------SKDLLVSAPQATVLMLFNEVEDDDPKSKTAG--------VLSYEQIA QSTGLQ-----GGELDRTLQSLACGKVR--VLTKSPKG------RDVSPTDTFTVNKAFT ---DPKFRIKIN------------------------------QIQMKETKEENR-ETHQR VAA-DRQFETQAAIVRIMKSR-KKMTHSQLVAEVIDQTKS-RGSVDPADIKANIEKLIEK DYLEREGGS-------YTYLA >Clavispora_lusitaniae_AAFT01000005.1| . LQLSKYCDNFFKQS------------------RKTKDVN-----------SFAQFEKEVV TVFKLI-TYKADFMLIYERDLSK--------RMLLGRS------------FNLALERKLL EAIL----GVVGE-GDEGSNLRAMFR-DVETSRSLYNPTPIDC----------------- ---------LPGVEFNAMVLEK-KFWPEIPGSG--------------------------- -------CDIALPNILSQALGEFSCKYEEQGE---KHKFHKLDWTNFLLHQIVLLVEFDS G------------QKELSINLLQASVLMLFEDVDE------------------IHYNELK MRTKME-----ERQLKKVLSSFTTERCP--ILILRG------------DVVIFNRSAELK ---NARTRVPMT----------------------------------REREIDATDDFSKV IEK-NRDPEVRAALVRTMKQS-KSILYAELLANVLHTMEQRGTSLLVHTVKEGIEYLISN EYIRRDADG-----VTLVYVP >Clavispora_lusitaniae_AAFT01000026.1| . ELLARYADGFLKAT------------------SKE-TD------------VANMTADNLV LVLKYV-ENKDVFENNYRRLLAK--------RLINANT------------KSDELEEGIL QRLQ----EGNSL--EFTSKITKMFQ-DMKSSQDLKGRVREIV----------------- -------GNSVVSDFTPLVLAQ-SMWPFTHLDD--------------------------- -------YNLKLAPELVRAIEVVEDEYTK------KHNGRELQW-LWNHGKSEVKANLAR RGK---------PPFIFTVTNVQLMILLAFNKATT------------------LTFSELH ETVGVA-----QHVFEAHLSPFTKFK----LLEQNPPD----AASFNAPNTTFTIVSEYK ---SKKLKVNFVSTIKN------------------------------EQKQEEV-DTTRE IDE-SRKNYLTASIVRIMKAR-KTMKHNDLVNEVLLQAHL-RFKAKLIDLKRAIEYLLDK EYIARCDGD------SYEYLA >Clavispora_lusitaniae_AAFT01000031.1| . ELLSVFMDSSIKQLSKANSSK-------RLATDANASVD-----------ETEEFLHNAV AFLKFI-KDKDAFEAHYAAHFAK--------RFLNSKISVSA---SSGGGYGGDLEELAI SKLS----EELGS--ASLEKITRMKK-DVNQSTELTREWKNYT----------------- -----SALELDLVELELKICHV-SDWPNSMTKDYKSFASVN------------------- -----GTVGFIWPSQFRETMKTFEEFWQTGK----KNDNKTLFW-CPKFGLMDLRITYPS K------------TYEINLSTYAGVIMMLFAPQSTDGDGNP---VLAFDEKRELTYEEIF ELTNIP-----EVDLKRQLQSIAVAPRLR-LLVKIPMS------KDVNPTDKFRLNDKFK AP-GNKVKVLTVSSSSS---------------------AKPESGKKSIKQEESD-EVKTN IEE-RRKHLVNAAIVRIMKSR-QTINHNDLIAELIKQLQN-QFQPLTLLIKQRIEDLIEK EYLERDNDT----PSIYHYVA >Coccidioides_immitis_ABBC01001139.1| . EYLSLFFDENLKKG------------------IKGKSEE-----------EVDILLENGI TLLRYI-RDKDLFETYYKKHLSR--------RLLMKRS------------VSMDAERQMI SKMK----MEVGN--TFTQRLESMFK-DMAISEDLSSSYKDHI----------------- --SQSNGPDPKRIELEMSILTS-TMWPMEIMGK--------------------------- --DSASHAPCNFPKNIDLLKQSFESFYLG------KHSGRKLTW-QAGMGSADIRATWVR PNGK-------TERHDLNVSTYAMIILLLFNDLPASES---------------LTFEEIQ ARTNIP-----THDLIRNLQSLAVAPKTR-VLKKDPMS------KEVKPTDRFYFNEKFQ ---SKFTKIKIG--------------------------VVSSSGNKVETKDERS-ETEKK MND-ERGGSVEAAIVRIMKQR-KRLAHSQLVNEVISQLAS-RFVPNVDMIKKKIESLIDR EYLERLPDVE---PASYGYIA >Coccidioides_immitis_NZ_AATX01000097.1| . ELLARYTDSLLKKG------------------LKTPEES-----------EYEELLAQIM TVFKYI-EDKDVFQKFYSRMLAK--------RLVHVSS------------VSDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DIQISKDLNASYKDWA----------------- ASTFDEEDRKKMVDPHFQILGT-GFWPLNPPTT--------------------------- --------QFIPPAEILKTTERFKSFYCD------KHSGRKLTW-LWQLCKGEIKANYIK N---------TKVPYTFQVSTYQMGILLLYNEHDT------------------LDYGEIE KATSLS-----PEILDPNLGILVKAK----VLLPSPED------GKPRAGTSYSLNYNFK ---AKKIKVNLN------------------------------IQVKSEQKTESE-DTHKT VEE-DRKLLLQSAIVRIMKSR-KKMKHVQLVQEVIQQVKA-RFPPKVPDIKKNIEALMEK EYIERLDGD------ELAY-- >Coccidioides_immitis_XM_001239676.1| . ------------------------------------------------DAELNKALDQVL DLFRFV-HGKAVFEAFYKNDLAR--------RLLMGRS------------ASDDAEKSML ARLA----SECGS--NFTHNLESMFK-DIDLARDEMASYNALL----------------- ----REKREKTNLDLYVNVLSS-AAWPSYPDVP--------------------------- ---------VKVPRIISSALSDFEHFYNN------KYNGRKLNW-KHSLAHCQLKARFPS G------------NKEIVVSSFQAIVLLLFNDVADGQ---------------TLSYHDIR DETGLS-----DIELKRTLQSLACAKYR--VLIKHPKG------RDINATDTFSFNTRFS ---DPKMRIKIN------------------------------QIQLKETKEENK-ETHER VAA-DRNYETQAAIVRIMKSR-KTISPQELIVEVIKATRN-RGDLDPADIKKNIDKLIEK EYMERDTES-----NKYKYIA >Coccidioides_posadasii_ABIT01003019.1| . EYLSLFFDENLKKG------------------IKGKSEE-----------EVDILLENGI TLLRYI-RDKDLFETYYKKHLSR--------RLLMKRS------------VSMDAERQMI SKMK----MEVGN--TFTQRLESMFK-DMAISEDLSSSYKDHI----------------- --SQSNGPDPKRIELEMSILTS-TMWPMEIMGK--------------------------- --DSASHAPCNFPKNIDLLKQSFESFYLG------KHSGRKLTW-QAGMGSADIRAMWVR PNGR-------TERHDLNVSTYAMIILLLFNDLPASES---------------LTFEEIQ ARTNIP-----THDLIRNLQSLAVAPKTR-VLKKDPMS------KEVKPTDRFYFNEKFQ ---SKYTKIKIG--------------------------VVSSSGNKVETKDERS-ETEKK MND-ERGGSVEAAIVRIMKQR-KRLAHSQLMNEVISQLAS-RFVPNVDMIKKKIESLIDR EYLERLPDVE---PPSYGYIA >Coprinopsis_cinerea_XM_001828254.1| . EMIAKYLDKQLRKG------------------QKGMKDA-----------EFQAELSRVL PLYRFT-EDKDVFRTFYHRMLSK--------RLLLGKS------------ASTDIEKWML KQLK----DKYDP--EF-GTAEDMFK-DLNLSRDLVEGFHRKN----------------- -------DNPESLKLNVMVLQQ-SVWPFSRPQT--------------------------- --------DVDLPVEMQDQLIKFTEYYKD------QHQGRTLHW-DPALGTVSLRASFKA G------------VKELSVSLYQAIILLLFNDQDD------------------IPFKDIA EQTRIE-----DAELRRTLQSLACGKKR--VLRKVPPG------RDVEDGDVFKFNADFT ---DPHHRVHIN------------------------------TIQAKVSAEESK-RTNIS IES-DRIHTIDAAIVRIMKAK-KELNYEQLKVATIDAVKN-HFVPSVDLIKKSIDSLVDR DYLTRNEED----MSKFVYVA >Coprinopsis_cinerea_XM_001835639.1| . ----------LRKN------------------NKVAEEG-----------DLEGALNRVM ILFKYI-EDKDIFQQFYTTKLSK--------RLIHGVS------------ASEESESSMI SKLK----EACGF--EYTNKLQRMQSPDMSLSKDLTDQFKTRM----------------- ----EQNHDDMDINFSIMVLGT-NFWPLTAPQH--------------------------- --------EFIIPEEMLTTYDRFQKYYQT------KHSGRKLTW-LWNYCKNELRTNYTN Q------------KYILMTSTFQTAILTQYNRNDT------------------LSLDELV TATSIP-----KDHLVQVLALLVKAK----VLIN-------------EETDQYDLNPGFK ---SKKIRVNLN------------------------------LPIKAETKAESK-DVMKT VEE-DRKYVIQATIVRIMKAR-KTMKNQALLDEVISQISQ-RFTPKVPDIKKAIDTLLEK DYIERVEGT----RDTFAYLA >Coprinopsis_cinerea_XM_001836445.1| . EYTSLFIDDHLKRG------------------LKGKSDD-----------EVDVVLGKTI TVFRYI-TDKDVFERYYKSHLAK--------RLLHGRS------------VNDDAERGML AKLK----LESGF--QFTSKLEGMFN-DIKLSNDAMVEYREYI----QSRTVWSPSIIAV TGLIYFAKKAPAIELSVTVMTT-TFWPISPPAV--------------------------- --------PCAVPDILAEACKSFEGFYFS------RHSGRRLTW-SMALGNADVRTRFKT R------------THDLNVSTYALIILLLFENLAESDF---------------LTYEEIK EGTGIE-----EHELKRNLQSLACAKFR--ILKKHPPG------RDIHEEDSFSFNHDFS ---EKMQRIKIS----------------------------TISSK-PETTRERQ-ETNER IDE-ERKFQIEACIVRVMKDR-KHLAHNALVNEVTKQLSS-RFHPDPLAIKRRIEGLIEK EYLERCE-D----RKSYNYLA >Coprinopsis_cinerea_XM_001839027.1| . ELIAKHADMLLRKN------------------NKMAEEG-----------DLEGALNRVM ILFKYL-EDKDVFQTFYTTKLSK--------RLIHGVS------------ASDEAEASMI SKLK----EACGF--EYTNKLQRMFT-DMSLSKDLTDAFKERQ----------------- -----QHAEDTDITFTVMVLGT-NFWPLNPPTH--------------------------- --------EFIIPQEITPTYERFQRFYQN------KHSGRKLTW-LWNYSKNELRTNYTN Q------------KYILMTSSYQMAVLMQYNRNDT------------------LSLDELV AATSIS-----KEILTQVLAVLVKAK----VLIN-------------EEPEQYDLNPGFK ---SKKIRVNLN------------------------------LPIRAEVKAESS-DVLKA VDE-DRKYVIQATIVRIMKAR-KTMKNQALIQEVISQITQ-RFAPKIPDIKKAIETLLEK EYIERVEGS----KDTFAYVA >Cryptococcus_neoformans_XM_568555.1 . ELLASYCDLLLRKS------------------NKDSDAE-----------SLEASLSKAM IIFNFI-DDKDVFHKFYQKKLAQ--------RLVGSLS------------ASDDAESSMI TKLK----ELSGF--EYTNKLSKMFT-DVNLSKDLMERFNERE----------------- ----REKGIASDIDFQPLVLGS-NSWPLHPQQT--------------------------- --------DFAIPREIQALYDRFNAFHGE------VHQGRTLNW-LWHISKNELRTTYLN Q------------KYILMTSAYQMAILTQFNVSDT------------------LSYKDIE AGTKLS-----PTVLKPQLGLLVKLK----ILLNTN--------------EEYSLNTGFK ---SKKIRVNLN------------------------------QTIKSEARAEQK-EVIAA VDE-DRKFVYQATIVRLMKGR-KTMQHQALIQEVTAQISS-KFTPKIPEIKKAIEYLIDK EYLERAPDS----NNTYNYLA >Cryptococcus_neoformans_XM_572097.1 . EWIAKHLDAAMRKG------------------QGSGTEE-----------QFNNHLDEIV TLIGFT-KDKDVFKAFYSSQLAK--------RLLLNKS------------ASNDQEKTMV AKLQ----KELGE--EFTS-GDVMMK-DLQLSETLVRSYQLAQ----------------- --SRGPAQYGETSNFTANVLTE-SAWPAYPLLK--------------------------- -----DGWNFHLTPSLQSSIDDFTSWYTT------QHKNRVLSW-RFQLATVTLTARFPS G------------RYEVGVSLFQAVVLLLYNEIES------------------LTFAEIK ERTGIE-----NNELVRTLQSLALGRKGTRVLLKKPSG------KEVNPTDIFAWNKGFT ---SERIKFKIN------------------------------QIQQDMSAEESR-KTNEQ VAL-DRVSILEATIVRIMKSR-KKLTLQLLIDGVVSDVSK-RFPPDVKEIKKRVESLIER EFMARDEED----RSILHYVA >Cryptococcus_neoformans_XM_769423.1| . EFLSLYIDETLKKGKGAKGVGIAGA-------GKGVTEE-----------EMEEAKEKTI RIFRFL-TDKDKFERYYKNHLAR--------RLLSGKS------------VGGDAEQEMV GRLK----KEVGF--QFTHRLEGMFT-DMRLSDEAANIFGNDP----------------- ------RYNDIPFTLHVSVLTS-SNWPPSTLLS--------------------------- -------LPLTFPAPLLPALEHYQTFYDS------RHSGRRLTW-QGLLGSADLKVRTRK G------------QWEVNLSTIGMVVLLAFSDLKPGDV---------------LSYHELK AQTSLP-----DAELARTLQSLACGKHR--LLVKHPKG------REVEQGDTFEFNEAFS ---SPLARIKILQISSSASSAASTS-------------ASSARGVGVENAQERE-ETERQ IEE-ERKHQVEACIVRIMKDR-KTMRHNDLVSEVAHQLAK-RFMASVPMIKKRIEGLIDR EYLERTE-D----MGSYRYLA >Debaryomyces_hansenii_CR382135.2 . FQLCKYCDSFFKNINKKS--------------NKDESIN----------LSFNEFQQHVL IIFKAL-NNKNDFISHYKKELSK--------RLLLGKS------------PSYSLERKLV ESFL----KLIGE-GEETVGLQIMFK-DLELSKEKYSLMTLDD----------------- ----------STVDFTALVLEQ-KHWPEMPKLD--------------------------- -------SDIILLPQLTTILDSFTALYHNSDE---KLKNRTLDWSHYPLHQLTIKANFDN G------------EKELDVNLLQAIVILLFNDKNS------------------YTYDEIF ALSNIS-----DKLLKKVLGSLSSDKYR--ILLKD--------------NATYSFNSKFT ---DKATKIKITLSKDR----------------------------EISTGLFDS-DATKA LER-NRSVEFRSALVRVMKSA-KRISYLDLLTQTLPLVEK-NGPCTIADLKSNLEYLIEN EFVKRELDG-----QSLSYIP >Debaryomyces_hansenii_CR382135.2| . ELLSIYMDFRIKQLTKNPGSSSKNIPTENDNDMNGSSID-----------QTDDLINKSV AFLRFI-KDKDAFEAHYANHFAK--------RFLNFKNSQA-GNSASNGKLGVDLEELII SKLG----EEMGT--TSLDKVIKMDK-DIKLSRDLTKDWRSYV----------------- ----NQNHKKSLIELDLKVCNV-SDWPKSMTKDYKKFSRDD------------------- ---TNNEIGFIWSRQLRSTIKEFEEFWFTNK----RNDNKSLFW-CPKFGSMDLRITYPT K------------TYDISMSTYAGIIMLLFAPQSTDADGNE---VLAFDEMRELAYDEIR ELTGIP-----EADLKRQLQSIAVAPRLR-LLVKIPMT------KEVNNSDVFKLNEKFK SP-STKVKVLTVSASSSASSG------------TKVSSTNDTTLAKTVQEEEFE-ELQSS ILE-GRKIEVNAAIVRIMKSR-RTINHNDLISELVKQLHN-RFQTLTILIKQRIEDLIEK EYLKRDDND----KSIYHYVA >Debaryomyces_hansenii_CR382136.2 . DLLARYADGFLKAT------------------SRE-SD------------IIGMTPDNLM IIFKFI-DDKDAFEEHYRRLLAK--------RLINNNT------------KSDELEESII QKLQ----EENSL--EYTSKMTKMFQ-DMKSSEDLKVNVREEL----------------- -----GQTDNQVKDFTPLILAQ-SMWPFKHLDD--------------------------- -------YKLKLAPELMPSFNKVQEIYNK------KHTGRQLQW-LWNHGKSEVKANLSR KGK---------PPFLFTVSNVQLMILLAFNKSNT------------------FSFKELF DTVGVA-----KHTFEAHLLPFTKYK----LIDQSPPG----AELFNKDDTKFTIVEEYK ---SKKLRVNFVSSIKT------------------------------EQKQEEE-NTNKE IDE-SRRNYLSACIVRIMKAR-KQMKHNELVNDVATQSLS-RFRAKIIDIKRVIDYLIEK EYLRRIDND------TYEYLA >Fusarium_oxysporum_AAXH01000595.1| . ---------------------------------------------GDEDAELDRQLDQAL ELFRFI-EGKDAFEAFYKKDLAR--------RLLMGRS------------ASQDAERNML TKLR----GECGA--NFTHNLEQMFK-DQELAKDEMESFKQWC----------------- ---QGSAERKNPLDLSVMILSA-AAWPTYPDVR--------------------------- ---------LNLPDEVATQIERFDKYYKN------KHTGRALTW-KHSLAHCSLKGIFAK G------------PKELLVSAYQAVVLMMFNSVPADG---------------FLAYEQIA TGTGLS-----GGDLDRTLQSLACGKAR--VLTKHPKG------RDVKPTDTFTFNKTFT ---DPKYRVKIN------------------------------QIQLKETKEENK-ATHER IAQ-DRRFETQAAIVRIMKSR-KSMGHSDLVAEVINLTKK-RGSVEPAAIKKEIE----- --------------------- >Gibberella_zeae_XM_380535.1| . EYVSLFIDDNLKRG------------------IKGKTEA-----------EVDVVLEKAI VLIRYL-QDRDLFQTYYQRHLAR--------RLLHGKS------------ESHDVEKQII SRMK----QELGQ--QFTSKFEGMFR-DLVTSTELTTGYRDHI----------------- --RSVGD-GTKTIDLNINVLTT-NYWPPEVMGR------------------------TAQ IGDG-SRVTCTYPPELDRLQTSFEQFYLT------NRNGRKLTW-IGTTGSSDIKCTFPA IAGKSGPLSR-ERRYEINVPTFAMVVMLLFNDLEDDQS---------------LTFEEIQ AKTNIS-----NQDLMRTLTAIAVAPKSR-VLLKDPAN------KSVKPGDKFTFNASFQ ---SKTIRIKAP---------------------------IINAVSKVEDTTERK-TTEEK NNQ-TRAHIVDAAIVRIMKSR-KELSHSQLTSEVLSQLSG-RFKPEVSLIKKRIEDLIAR EYLERPDEDG--APSLYRYVA >Gibberella_zeae_XM_385696.1 . EMIAKYIDMLLRGGLKSLPKELLSD-----LKDRETAQKEGQASTGDEDAELDRQLDQAL ELFRFI-EGKDAFEAFYKKDLAR--------RLLMGRS------------ASQDAERNML TKLR----GECGA--NFTQNLEQMFK-DQELGKDEMESYKQWC----------------- ---QGSADRKAPLDLSVMILSA-AAWPTYPDVR--------------------------- ---------LNLPDEVATQIERFDKYYKN------KHTGRVLTW-KHSLAHCSVNARFAK A------------PKELLVSAYQAVVLMMFNSIPDGG---------------FLAYEQIA TGTGLQ-----GGDLNRTLQSLACGKAR--VLTKHPKG------RDVKPTDTFTFNKTFT ---DPKYRVKIN------------------------------QIQLKETKEENK-ATHER IVQ-DRRFETQAAIVRIMKSR-KSMGHSELVAEVINLTKK-RGSIDTSAIKKEIESLIEK DYIEREGNA-------YVYLA >Gibberella_zeae_XM_389792.1| . ELLAKYADVLLRKS------------------STSIEES-----------ELEHTLNQIM TVFKYI-EDKDVFQKFYSRMLAR--------RLVNSNS------------SSDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DMQISGDLNKEFRVHL----------------- ----EGVESTKVVDSTFSILGT-GFWPLTAPST--------------------------- --------DFNPPPEIAAEIERFTRFYKH------KHDGRKLTW-MWNLCKGEIKASYCK A---------SKTPYTFQVSIYQMAILLLFNEKDS------------------YSYDDIL STTQLS-----KEVSDQAIAVLLKAK----VLIMSGAAG-----EKPGSGKTFKLNYDFK ---SKKIRINLN------------------------------IGGVKEAKQEEV-ETNKT IEE-DRKLVLQSAIVRIMKAR-KKMKHTQLVSETINQIRS-RFVPKVGDIKKCIEILLDK EYLERLEDD------ELGYLA >Kluyveromyces_lactis2_CR382126.1 . ESFDSNRKAIMKNMI-------------TLTFNADIKNIE----------KVDRWLCKVS EEGQFS-GIKDLVRSCCIFMNDIFPPDSKQDELLWNIY------------KRKYFLRSVL KSLG-------GS--EQLIKTNERF--DQQLLCCGLLKSVHIL----------------- ----ELQQLNDELIESLRMKRAPKITPVILKQS-----------------------NISD SLDSSEISGLILPEPLNGMVNKQWEYYKVLD----RNDHKTMSL-QCQLNLLELKSPFRH GIS--------SEIVILHVNLLQASIFHLFNNSAR------------------LSLEQIK NTLTET--KHNIPQIDSNMEMFLQMN----MFKKDSED-------CFYLNTKYKP--KKE A--LNDGKLTLYH------------------------------LPKISPKIMEN--DKAD NRW--FTEIVCACIIRTLKQR-RKCTKTKLFEYVASAFPG----ISRGEFKDALGRC--G EYYTSENGN-------VQYLL >Kluyveromyces_lactis_CR382123.1| . EFLSLYFDNYLKSE-----------------------PS-----------AMDSNIRKCV QFFKLF-KDKDAFEIIYRQQLSR--------RLLQQRS-------------NVLREQELI FLLQ----EDVGT--SYTSKLRGMLR-DLHSSNTFMQKNGKLS----------------- ----------KTRDISVNVLTN-MFWPLQGSDM--------------------------- ------NRDVIVPDSFAAIRNEYENRYAK------THSGRLLEW-NYHLSTVEIAYQFRN S------------YHELSMPMFSGIIFMLFKEHES------------------LTFDEIV ELTNLP-----QQEVRKNLISMSVAPKTK-ILQKSPPG------KSISNTDMFSINQGFT AP-QRKVKVLMV---------------------------LMNTRPNATNDSTRS-SVEKK LLD-SRLSVINAAVTRIMKQD-RKLYHSELQDKVALSIP--LFEMSPSLFKMSLEYLLNN EYIQRDFDN----TTMYHYLP >Kluyveromyces_lactis_CR382126.1 . EMLAKYSDQLLKKS------------------TKNNE-------------QVDLTVDDIM TVFKFL-ADKDAFEMHYRKNLAK--------RLIHGSS------------KSEADEEIII QRLQ----SENSL--EYTSKITKMLQ-DVKLSKNLHDEFSTFI------------SQDGN NTTSAATFRSKVPELEPLILAD-NVWPFSYQPT--------------------------- --------EFALPPVLEHSKNKLETMYTD------KHSGRILKW-LWPMSRGEIKAHIGK PGK---------PPFQFTVTIFQMAILTLFNDIST------------------LTFEQIQ ERTNLK-----ATQIASNMYPFVKMK----LLIQSPEG----VESMIKLDTKYTLNKPYR ---LSKTSVNFAAAVKNDLTFTATVN---------------GSALDETEASEQK-KAEKE LNQ-QRLMFLRACIVRIMKAK-RKLPHSSLMNECIAESQQ-RFNAKVSMIKKAVDNLIEQ EYLKRTDDG-----ECYEYLA >Kluyveromyces_waltii_AADM01000138.1| . EYLAIYMDTLLRLP--------------------ASAEN-----------ISKESLEECT AIFKAL-REKDIFERVYKQQLSK--------RLLQQRS-------------SLKVEKQVI SKMK----EEVGS--TFTSKLEGMFR-DMMISQSYNAKFQQSY----------------- ---------GAPFPYEANVLTS-TCWPFQGVNA--------------------------- -----DEEEVVLPTDLERLKLDFENFYIK------NHSGRSLRW-AYHLGSMEIGFQFAR S------------YHEISMPVYAGVIFMLFENYEE------------------LTMQEIS NLTRMP-----EHELVRHLLTLSVAPKTR-LLKKRPLT------KTILPTDRFNINQSFQ AP-TTKVKVLAV---------------------------LPKADSGFPGSTSLD-DSFQS VIK-DRKGSVEAAIVRSLKSL-KSSDYDSLFENVQSCLSD-KFSVSKAIFKESLERMCER EYVQHDPDD----ASFYHYL- >Kluyveromyces_waltii_AADM01000292.1| . EMLAKYSDQLLKRS------------------NKAGES------------TSELSADDIM TVFKFL-TDKDAFETHYRRLFAR--------RLIHGTS------------TSEEDEELVI QRLQ----SENSM--EYTGKITKMLQ-DIRLSKQLEKEFESAI----------------- -KIAPDYSRPKYPDFQPFVLAE-TMWPFSYQDV--------------------------- --------EFNLPQELVPTHRGLEKLYTN------KHNGRVLKW-LWPLCRGEMVADIGK PGK---------PPFIFTVTLFQMAILLLFNERST------------------VTLEEIQ DHTNLS-----TSNIASSIIPFIRWK----LVQQSPPG----LDALSRPDTQFKLSTPYK ---AMKTKINFAAGVKSDI-SGVSAT-----------------AGKNGEPSEGQ-KIEKE LST-ERQIFLEACIVRIMKAR-RKLPHATLVNECIAQSHQ-RFNAKVSLIKRAIDNLISK EYLQRCDDG-----ESYEYLA >Laccaria_bicolor_XM_001875865.1| . ----------LRKN------------------NKLAEEG-----------DLEGALNRVM ILFKYI-EDKDVFQTFYTTKLSK--------RLIHGVS------------ASDESEASMI SKLK----EACGF--EYTNKLQRMFT-DMSLSKDLTDQFKSRM----------------- ----EQTHDDMDISFTIMVLGT-NFWPLHPPPH--------------------------- --------EFLIPAEILPTYDRFQKYYQM------KHSGRKLTW-LWNYSKNELRTNYLN Q------------KYILMTSTFQMAVLLQYNKNDT------------------LSLSELS AATSIP-----KDYLGQVLAILVKAK----ILINEETD-----QYDLNPGGSIQLAICFK ---SKKIRVNLN------------------------------LPIKAETKTEST-DVLKT VDE-DRKYVIQATIVRIMKAR-KTMKNQPLIQEVISQISQ-RFAPKIPDIKKAIDTLLEK EYIERVEGT----RDTFAYMA >Laccaria_bicolor_XM_001876910.1| . ----------LRKN------------------NKMAEED-----------DLEGALNRVM ILFKYL-EDKDVFQTFYTTKLSK--------RLIHGVS------------ASDESEASMI SKLK----EACGF--EYTNKLQRMFT-DMSLSKDLTDSFKERM----------------- ----SQNHDDMDITFSIMVLGT-NFWPLNPPPH--------------------------- --------DFVIPTEIVPTYDRFQKYYQT------KHSGRKLTW-LWNYSKNELRTNYTN Q------------KYILMTSSYQMAVLLQYNRTDT------------------LSLDELV TATSIT-----KDILTQVLAVLVKAK----VLIN-------------EEKDQYDLNPNFK ---SKKIRVNLN------------------------------LPIKAEVKAESS-DVLKA VDE-DRKYVIQATIVRIMKAR-KTMKNQALIQEVISQISQ-RFAPKIPDIKKAIETLLEK EYIERVDGS----KDTFAYVA >Laccaria_bicolor_XM_001880703.1| . EFISLFIDDNLKRG------------------LKGKTEN-----------EVDVVLDKTI TVFRYI-SENDVFERYYKGHLAK--------RLLLGRS------------VSDDAERGML AKLK----IECGY--QFTQKLEGMFH-DMKLSADAMVTYQEHL----------------- -----SKTTAPEIDINVTVMTS-TFWPMSHSAS--------------------------- --------PCNVSAEMGKACKSFEQFYLS------RHSGRRLTW-QYSLGNADVRVRFKA R------------THDVNVSTFALVILLLFEDLPNEEF---------------LTYGDIK EATAIE-----DLELKRHLQSLACAKFK--ILKKHPPG------RDVFDDDSFSFNTGFT ---SSNQKIKIS----------------------------TISSK-VESSEERQ-ETRDR IDE-ERKHQMEACIVRIMKDR-KHLSHNDLVNEVTKLLLS-RFQPEPLAIKRRIENLIER EYLERCT-D----RKSYNYMA >Laccaria_bicolor_XM_001884536.1| . EMIAKFLDKAMRKG------------------QGSSTDA-----------EFQALLDSVL ALYRYT-DDKDVFRTFYHRSLAK--------RLLLEKS------------ASIDFEASML KKLKEVLGAEYDP--EF-GMGEDMFK-DLSLSKEAMAEYHAKL----------------- ------PSNSFGQRLSVMVLQR-SAWPFTVTKK--------------------------- --------SVDLPISMQKELVNYANDYKL------RHSGHVLSW-DHALGTATLKARFDA G------------YKDLSVSLYQAVVLLLFNDAVE------------------IPFTDIM AQTRMD-----DDELRRTLQSLACGKKK--VLLKIPPG------KDVNDGDVFKFNADFK ---DERLRVHIN------------------------------SIQAKVTPEESK-RTNET IEG-DRKHYIDAAIVRIMKAK-KEMMHEQLMIATIDAVKS-HFVPIVDTIKKRVESLVES EYLRRSEKD----KEKFFYVA >Laccaria_bicolor_XM_001891143.1| . ELIAKYLDMLLRKN------------------NKMAEED-----------DLEGALNHVM ILFQYL-EDKDVFQTFYTTKLSK--------RLIHGVS------------ASDESEANMI SKLK----EACGF--EYTDKLQRMFT-DMSLSKDLTDSFKDCM----------------- ----SQNHGDMVITFSIMVLGT-NLWPLYPPPH--------------------------- --------DFVIPTEIVPTYDRFQKYYQT------KHSGRKLTW-LWNYSKNELRTNYTN Q------------KYILMTSSYQMAVLLQYNWADT------------------LSLDELV TATSIT-----KDILTQVLVVLVKVK----MLIN-------------EEKDQYDLNHNFK ---SKKIRVNLI------------------------------QPIKAEVKTESS-DVLKA VNE-HRKYVIQATIVRIMKAR-KTIKSQALIQEVISQISQ-RFAPKIPDIKKAIEILLEK EYIERVDGS----RDTFAYVA >Lodderomyces_elongisporus_XM_001527352.1| . ELLAKYADGFLKTS------------------AKD-SD------------IVDMNADNLM IVFKFI-NDKDTFEEHYRRSLAK--------RLISGTC------------KSDELEEGVI HRLQ----EENSI--EYTSKMTKMFS-DMKASEELKLKVKEKL---------------NQ ADSSNESNNGLIKDFNPLVLAQ-SMWPFRHVPD--------------------------- -------YDLNVAPELQSPFGHLKEVYTE------QHSGRQLQW-LWNHGRAELKANLSR KGK---------PPFSFTVSNVQLMILFAFNKQNS------------------YTFRQLH EIVGTK-----KETFEAHLLPFTKFK----LIDQSTPS--------ITDDTVFTIVEEYK ---SKKLKVNFISAIKT-----------------------------NEVRQEED-EASKE IDE-ARKTYLQACIVRIMKLR-KQMKNNELINEVLPQTSS-RFKAKIIDVKRVIDLLIEK EYLKRLDNE------TYEYIS >Lodderomyces_elongisporus_XM_001527455.1| . --------------------------------ISSHSGD-----------EIENLINNSI QILRFV-KDKDAFEAYYANHFAK--------RFLNSKSTLGS-----AFSKGNDVEEMIL SKLC----EEMGT--TSLDKVIKMSK-DIKISNDTTNGWKRYL----------------- --AKANIPVSNLIDLDLKICNV-AVWPKSLTKDYKSFEKTERAIEDGTVAGSGNRNGNGT ENGGDTGTKFVWPRQLRNTIQEFEEYWSSGK----KNDNRSLHW-SPKFGSIDMRITYPS R------------TYDINLPVFAAIIMLLFAPQSLLTDKNGPC-KLAFEERKVLSYTEIV ELTGIP-----LQELKRHLQSIAVAPRLR-LLVKSPMS------KEVNDSDTFRLNEKFK SP-TPKVKVLTVSLASSSSSSSTSSSSKMS--SSLATVTAGKSNKKTEQEEETA-EVNAQ IIE-GRKIELNAAIVRILKSR-RTVSHNELIEGLIRQLSN-RFQPTVVMMKQRIEDLIEK EYLKRDDND----RNLYHYIA >Magnaporthe_grisea_XM_364064.1 . ERVAKYIDMLLRGGLKALPPSLMGD-----YKDRTETERADVASAGDEDAELNRQLDNGL ELFRFI-QGKDVFEAFYKRDLAR--------RLLMARS------------ASQDAERTML AKLK----VECGS--QFTHNLEQMFK-DQEVGKEELAAYKEWR----------------- -RSSDRANKLSKIDLNVNVLSA-SAWPSYPDDP--------------------------- --------AVALPAGVLENLQHFEQYYKN------KHEGRKLTW-KHSLSQCVIKATFPR G------------TKELVMSAHQAAVLAIFNSVEIDE---------------PLSYEEIE KASGLS-----GDLLQRTLQSLACGKAR--VLAKAPKG------REVGKEDTFTVNKGFT ---DPKIRIKIN------------------------------QIQLKETKAENK-ETHER VAA-DRQFETQAAIVRIMKSR-KTLPHAQLVAEVIEQTRR-RGALEPAEIKANIEKLIDK EYIEREGGN-------YVYMA >Magnaporthe_grisea_XM_367220.1 . ELLAKYTDVLLRKS------------------GSAVEEE-----------ELENTLSQIM TVFKYI-EDKDVFQKFYSRMLAR--------RLVHTNS------------SSDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DMQISKDLNTGFREHA----------------- -----EKSEMKVLDSQYAILGT-GFWPLQVPNT--------------------------- --------AFNPPAVISEDCERFTRFYKN------KHDGRKLTW-LWQLCKGEVRATYCK Q---------SKVPYTFQVSMYQMAILLMFNDGDR------------------HTHEEIA STTSMN-----SETMDPVLGLLLKAK----VLLADS--------DKPGPGTTYSLNYDFK ---NKKVRVNLN------------------------------IGLKTEQKQEEV-ETNKT IEE-DRKLLLQSAIVRIMKAR-KRMKHNQLVSETIGQIKG-RFVPKIPDIKKCIEILLDK EYLERLEDD------DLGYLA >Magnaporthe_grisea_XM_367827.1| . EFVSLYIDENLKRG------------------IRGKSDL-----------EVTAILDRSI VMIRYL-KDKDLFERYYQKHLGR--------RLLHSRA------------SSEEAEKQLI TMMQ----LELGK--HFTSKFEGMFK-DITISEELSTKYGEHI----------------- RSLGDVDVHHKPIDLAISVLTS-NSWPPDVMGR----------------------PAQVG RGDGPPAVDCNYPPEIKRLQDSFFKFYLK------DRSGRVLTW-IGSAGSADIKCVFPP VKGM-SGPLSRERRYELNVSTYGMVVLMLFNSLEDGET---------------LSFEDIQ AETSIP-----PKDLSRALASLSINPKAR-VLLKDPAT------KTIRPGDKFSFNAGFV ---SKAIKIKAP---------------------------VINSQSKVEGDEERQ-RTEDK NDE-TRRHMIDAAIVRIMKSR-KELAHNALLAEVIGQLVS-RFQPDVAMIKTRIEDLIAR EYLERLD-D-----SGYKYMA >Malassezia_globosa_XM_001730219.1| . EYISLFIDEHLRKG------------------TRAADDT-----------TLEQMLDKTI TIFRYI-HEKDVFERYYKMHLTR--------RLLHNRS------------VSDDAERSMI AKLK----VECGH--GYVQKLQGMLN-DMKLSEEVLAAFHRAQ----------------- ----EREQRQLPLQMNVHVLTA-TYWPISSPTE--------------------------- --------PCTLPPALLEACESFEKFYGT------RHRGRVLTW-QPTLGTAEVRVRFKT R------------THELVVSTYALMVLLLFEHSDT------------------LSYRDIR AATRMP-----DVDLQRTLQSLACAKYK--VLQKEPKG------RDVHETDLFSFHADFT ---CPLARVKIA----------------------------QIAAK-VESPQERK-ETTAK VEE-ERKNQVEACIVRIMKSR-KTLAHNDLVHEVVHQLLP-RFQPSPALIKKRIESLLDR EYIERTE-A----RHVYQYVA >Malassezia_globosa_XM_001730281.1| . ELLAKFIDALLKKH------------------SRGGDEES----------SLDESLDAAM IVFKYI-EDRDYFQKFYAKFLSR--------RLVSFAS------------ASTDAEESMI ARLK----EACGF--EYTSKIQRMFT-EAGLSKELNDRFQESG----------------- ------MLQNKELSFYSFVLTS-GVWPLQAPQT--------------------------- --------DFLVPAELQSTYDEFTRFYHK------QHTHRQLAW-LWHLSTNELHTNYLS R------------KYIFTTSTYQTAVLLLFNSETV------------------LTFDEIA AATRLD-----KSTLHAALVPLVKLK----VLHLLD--------------DSYSLNMDFK ---AKKVRINLH------------------------------IPVRAEQKVESA-EVART VHE-DRKVLLQATIVRIMKAR-KTYKHNLLLNEVILQLQS-RFHPKVPDIKKAIDTLIEK EYLQRVEGE----KDTYSYVA >Malassezia_globosa_XM_001732227.1| . ELLANYIDAELQKG------------------RGLVDSS-----------MPEACMDDVL FLFRCL-HHKDLFEEYYQRAFAR--------RLLLRCS------------ASDDAERAVI LRLK----HECGP--DYTRKLETMLK-DMHLSDNLRSAFAEAG----------------- -------GASTPFEFEVDVLTQ-AHWPPFHDAP--------------------------- ---------LILSSSMQSALLRYETFYHT------CHSGRSLHW-CHALGSLLVRADLGE A-----------GVKDLVVSTLQAAVLLVFNVRDV------------------QTFSELE QATHMP-----LHELQRTLQSLACGPARTRILRKIPPG------GEVRESDSFMVNEQLS ---NARRRIKLN------------------------------QLQQRDSPEERR-TSTEH VLM-DRDVLLQASAMRVLKAH-KLISHADLTTAVIEQVKS-RFPVETAELKRAFERLIEK DCMERVDGD----RQVYRYVA >Malassezia_restricta_AAXK01002082.1| . ---------------------------------------------------LEPVLDKTI TIFRYV-HEKDVFERYYKMHLTR--------RLLHNRS------------ASDDAERSMI AKLK----VECGH--GYVQKLQGMLN-DMKLSEEVLRAFHHTL----------------- ----EREGTSLPLQLNVNVLTA-TYWPIASPKE--------------------------- --------PSIFPPALTEACNAFEKFYDT------RHRGRVLTW-QPSLGTADVRVQFKS R------------THELVVSTYALMVLLLFEHADV------------------LTYGHIR DATRMP-----DADLQRTLQSLACAKYK--ILRKEPKG------RDVSENDSFVFNADFT ---CPLARVKIA----------------------------QIAAK-IETPQERQ-ETNVK IEE-ERKNQVEACIVRIMKSR-KTLAHNELVNEVVQQLMQ-RFQPSPALIKKRIESLLDR --------------------- >Microsporum_canis_ABVF01000165.1| . EMIAKHVDQLLKGGVRAMQ-------------NRPVEDITGNASLTDEDAEINKQLDQVL DLFRFV-HGKAVFEAFYKNDLAR--------RLLMGRS------------ASDEAEKSML SRLK----SECGS--NFTHNLETMFK-DMDLARDEMASYNALL----------------- ----REKNERPKVDLNVNVISA-TAWPSYVDVP--------------------------- ---------VNIPESISRAITNFEEFYNN------KYSGRRLHW-KHTLAHCQLKARFPL G------------DKELVVSSFQAIVLLLFNDVAGSE---------------TLSYPVIK QASGLA-----DVELKRTLQSLACAKYR--VLLKKPKG------KEVNEDDVFAYNSKFE ---DQKMRIKIN------------------------------QIQLKETKQENK-TTHER VAA-DRQYETQAAIVRIMKSR-KVITHSDLVAEVIKATKN-RGQLELGDIKKNID----- --------------------- >Microsporum_canis_ABVF01000294.1| . EYLSLFFDENLRKG------------------IKGKTEE-----------EVDTLIDNGI TLLRYI-RDKDLFEVYYKKHLSR--------RLLMKRS------------VSMDAERQMI AKMK----MEVGN--TFTQRLESMFK-DMAVSTDLTSNYRDYI----------------- --SRQGDPDPKRVELEMSVLTS-TMWPMDIMSS--------------------------Y NRNGQVQPPCVFPKNIESLKQSFERFYLD------KHSGRKLSW-LPGMGTADIRATFRR PNGK-------VERHDLNVSTYAMVILLLFNELPVGES---------------LTFEEIQ EQTNIP-----TNELIRNLQSLAVAPKTR-VLRKEPMS------KGVQPTDRFFFNDQFT ---SKFTRLKIG--------------------------VVSSGGNKVENKEERT-ETEKK TSD-ERGGTIEAAIVRIMKQR-KKLAHSQLITEVISQLAA-RFTPDVNMVKKRIESLIDR EYLERVTDSD---PPAYTYVA >Neosartorya_fischeri_XM_001259429.1| . EMIAKYVDRLLKGGWKLAP-------------GRNMADVP----LADEDAEINRQLDQVL DLFRFV-NGKAVFEAFYKNDLAR--------RLLMGRS------------ASDDAEKSML ARLK----TECGS--TFTHNLESMFK-DMDVARDEMAAYASIQ----------------- ----RERRKPLPIDLNVSVLSA-SAWPSYPDVQ--------------------------- ---------VRIPPVVAEAIDDFETFYYN------KYNGRKLNW-KHQLAHCQLRANFSR G------------QKELVVSSFQAIVLLLFNDVPEGG---------------SLSYAQIQ EGTKLS-----DQELQRTLQSLACAKYQ--VLTKKPKG------RDVNPTDEFSFNAGFT ---DPKFRIKIN------------------------------QIQLKETKEENK-KTHER VAA-DRHLETQAAIVRIMKSR-KQISHAELVAEVIKATRS-RGVLDVAEIKNNIEKLIEK DYMERDTETS---PNMYKYVA >Neurospora_crassa_XM_322357.1 . EMIAKHIDMLLRGGLKTLPKALLSD-----VKDRQDAERSGIASTADEDAELDRQLDHSL ELFRFI-QGKDIFEAFYKKDLAR--------RLLMGRS------------ASRDAERNML AKLK----NECGS--SFTHNLEIMFK-DQELAKDEIASYKTWL----------------A GRGEDSPVANSELDLSVNVLSA-AAWPTYPDVR--------------------------- ---------VLLPQNVLDHITTFDTYYKS------KHTGRRLTW-KHNLAHCVVKARFDR G------------PKELLVSAFQAIVLVLFNEAEEKSPDG------------ILSYEQLA SATGMP-----DPELQRTLQSLACGKTR--VLNKHPKG------RDVNKTDTFSINKSFT ---DPKFRVKIN------------------------------QIQLKETKEENK-ETHER VAQ-DRQFETQAAIVRIMKSR-KKMAHAQLVAEVINQTKQ-RGAVDAADIKANIEKLIEK DYIEREGGN-------YVYLA >Neurospora_crassa_XM_324560.1 . ELLAKYTDVLLRKS------------------STGVEEA-----------ELENTLTQIM TVFKYI-QDKDVFQKFYSRMLAR--------RLVHSNS------------NSDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DMQISKDLNTGFKEHV----------------- ---ASLNMDGKPLDSTYSILGT-GFWPLVPPNT--------------------------- --------SFVAPAEISADCDRFTRFYKN------KHEGRKLTW-LWQLCKGDIKANYMK G---------AKMPYIFSVSAYQMAILLLFNEKDQ------------------YTFEELA SITQLN-----ADVLEGALGILVKAK----VLTAEGGEG-----GKIGPGATFSLNYDFK ---NKKYRINLN------------------------------VGMKSETKQEEA-ETNKT IEE-DRKLLLQSAIVRIMKAR-KKMKHQQLVSETINQIKA-RFMPKIGDIKKCIEILLDK EYLERLEDD------ELGYLA >Neurospora_crassa_XM_331696.1| . EYVSLFIDDNLKRG------------------IKTKTEA-----------EVDAVLDKAI VLLRYL-TDRDMFERYYQKHLAK--------RLLHGKS------------EI-HTEKEMV SRMK----SEMGN--HFTSKFEGMFK-DMELSKDLTDNYRDHI----------------- --ASLGDADYKMVDLNINVLTT-NNWPPEVMGG------------------------GTS KGEG-AKLDCFYPPEIKRLQESFYKYYLK------DRSGRVLTW-VSSAGNADIKCVFPK VPGKETGPLSKERRYELNVSTYGMIVLMLFNDLVDGES---------------LSFDEIQ AKTNIP-----APELMRTLASLSSVPKCR-VLLKEPAT------KNVKNTDKFSYNAQFV ---SKAIRIKAP---------------------------VISSISKVEGDEERK-ETERK NDQ-TRAHVIDAAVVRIMKQR-KLLAHTKLVNEVISQLMG-RFKPDVPLIKKRIEDLLAR EYLERVEGD----SSTYRYLA >Paracoccidioides_brasiliensis_ABKH01000102.1| . EYLSLFFDENLKKG------------------VRGKTEE-----------EIDALLESGI TLLRYI-RDKDLFETYYKKHLSR--------RLLMKRS------------ASTDAERQMI EKMK----MEVGN--TFTQKLEAMFK-DMELSSGLTSKYANYI----------------- --SQQE-SDSKRIDLEINVLTS-TMWPMEMMTN--------------------------S NKDGTLATQCTYPKNIELLKQSFEQFYLG------QHNGRKLQW-QSGMGTADIRATFPR PNGK-------VARHDLNVSTYAMVILLLFNDLGADES---------------LSFEEIQ ARTNIP-----TNELSRNLQSLAVAPKTR-VLKKEPMS------KDVKSTDRFFFNEGFH ---SVYTKVKIG--------------------------VVSSAGNKVENKDERN-ETEKK MND-ERGGGIEAAIVRIMKQR-KKLSHTQLMTEVISQLAS-RFTPEVNMVKKRIESLIDR EYIDRIPDSE---PPAYVYHA >Penicillium_chrysogenum_AM920428.1| . ELLAKYTDSLLKKG------------------SKSAEES-----------ELEEMLVQIM TVFKYI-EDKDVFQKFYSKNLAK--------RLVHVSS------------VSDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DMQISKDLNNNYKVWQ----------------- DKVLDDDDRKRMTDAHFQILGT-GFWPLNAPTT--------------------------- --------PFLAPPEIVRTAELFQKFYFD------KHNGRKLTW-LWQLCKGEIKANYVK N---------TKVPYTFQVSTYQMGILLLFNEADT------------------LTYGEIE KATTLA-----TEILDPNLSILLKAK----VLIASPEG------AKPEPSTSFTLNYNFK ---SKKVKVNLN------------------------------IQIKSEQKVEAD-DTHKT IEE-DRKLLLQSAIVRIMKSR-KKMKHVQLVQEVIQQVKS-RFPPKIPDIKKNIEALMEK DYIERMDGD------EISY-- >Penicillium_marneffei_XM_002145022.1| . EMIAKYVDNLLKGGLKVI--------------GKQAEDAE----LADEDTEINKQLDKVL DLFRFV-HGKAVFEAFYKNDLAR--------RLLMGRS------------ASDDAEKSML ARLK----TECGS--SFTHNLEAMFR-DMDLARDEMSSYNAYK----------------- ----TQRRDKFSLDLSVNVLSA-AAWPTYPDVP--------------------------- ---------VRIPPDIARAINDFEQYYHT------KHNGRKLSW-KHQLAHCQLRSRFDK G------------NKEIVVSSFQAIVLLLFNDVTDGE---------------TLSYSQIK EATGLS-----DPELKRTLQSLACAKYR--VLTKKPKG------KDVNDTDEFAYNGAFQ ---DPKMRIKIN------------------------------QIQLKETKEENK-TTHER VAA-DRHYETQAAIVRIMKSR-KTITHAELIVEVIKATRS-RGVLEQAEIKKNIEKLIEK DYMEREEGN------RYSYLA >Penicillium_marneffei_XM_002146208.1| . ELLARYTDSLLKKG------------------SRATEES-----------ELEEMLTQIM TVFKYI-EDKDVFQKFYSKALAK--------RLVHVSS------------VSDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DIQISKDLNASYRDWQ----------------- EKVHDEEDRKKMVDPHFQILGT-GFWPLNAPST--------------------------- --------EFIPPTEIVKTAERFQHFYFD------KHSGRKLTW-LWQLCKGEMKANYIK N---------TKVPYTFQVSTFQMGILLLYNEHDS------------------LDYDEIQ KATKLA-----NEVLEPNISLLLKAK----VLIASPEG------SKPASGVSFTLNHNFK ---HKKVKVNLN------------------------------LAIKSEQKTEAD-DTHKT IEE-DRKLLLQSAIVRIMKSR-KKMKHVQLVQEVIQQVKA-RFPPKIPDIKKNIEALMEK DYIERLDND------ELAY-- >Penicillium_marneffei_XM_002146704.1| . EYLSLFFDENLKKG------------------IKGKTDA-----------EVDSLLDNGI TLLRYI-RDKDLFETYYKKHLSR--------RLLMKRS------------VSMDVERQMI SKMK----MEVGN--QFTQRLEAMFK-DMAVSEDLTNNYKAHM----------------- --SRTA-ADSKRFELEISVLTS-TMWPMEIMSS--------------------------S KDD-DAQLPCIFPKDVDTVRQSFEKFYLD------KHSGRKLSW-QASMGTADIRATFPR AEGK-------YARHDLNVSTYAMIILLLFNDLPLDDS---------------LTYEEIQ ARTRIP-----DHDLIRNLQSLAVAPKTR-VLKKDPMS------KDVKRTDRFFYNASFK ---SQFTKVRIG--------------------------VVSSGGNKVENQNERS-ETEKK MNE-ERGGTIEAAVVRIMKQR-KKLAHSQLLTEVLSQLAA-RFVPDVNMIKKRIESLIDR EYLERIPDSD---PPAYSYVA >Phaeosphaeria_nodorum_XM_001793342.1| . EYISLFIDENMKKG------------------IKGKTEM-----------EIDTVLEKAI ILLRYV-QDKDLFERYYKKHLCR--------RLLMNKS------------ISNEVEKQMI SKMK----IELGN--NFTLKLEAMFK-DMTISEELTAGFKKHV----------------- --EGLGDREPKRIELAINVLTS-MTWPLETMGG------------------------VVA EEDQ-SRPRCNFPAVVDKVKRGFEKYYSQ------KHSGRQLTW-LPNMGSADIKAVFPK VVQKDGSFK--ERRHDLNVSTYGMIILLLFNDLPADQH---------------LTFEEIQ AQTNIP-----RSDLIRNLQSLAVAPKTR-ILVKEPMS------KDVKPTDRFSFNEGFN ---GKFVKIKVG--------------------------VVS-NGNKVESDRERR-ETEKK NDD-SRQFCIEAAVVRIMKQR-KELSHQQLVSETLGQLAG-QFKPEVNMIKKRIESLIER EYLERIDGAK---IDSYRYLA >Phaeosphaeria_nodorum_XM_001803466.1| . ELLAKYTDTLLKRSS-----------------AKMSEED-----------DMEKLLTQIM TVFKYI-EDKDVFQKFYSRMLAK--------RLVQTTS------------ASDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DIQISKDLNSAFKEWQ----------------- SNNLDEADMKTNVDASYHILGT-GFWPLNPPTT--------------------------- --------PFTPPQLIVQTYDRFARFYNH------KHQGRKLTW-LWQLCKGEVKANYCK VLN-------SKASPTFQVSTYQMGIMLLFNDSDT------------------VTYDEIA EATKLN-----KETLDPSLGVFLKAK----VLIAQPEN------AKTESGTTYKLNTAFK ---TKKAKINLN------------------------------IGIKSEQKAEAE-DTHKT IEE-DRKLLMQSAIVRIMKSR-KKMKHQQLVSETIQQIKN-RFMPRVPDIKKCIDILLEK EYLERLEGD------ELGY-- >Phaeosphaeria_nodorum_XM_001806139.1| . ------------------------------------------------DTEVDNQLDQVL DLFRFV-HGKAVFEAFYKKDLAR--------RLLMGRS------------ASADAERSML SRLK----TECGA--GFTANLEQMFR-DIELSREEMASYKSIS----------------- ----EERNERLAVDLNVSILSA-SSWPTYPTVT--------------------------- ---------VIIPPQIKQAIDKFEAHYKA------KHSGRKLEF-KHALAHCQLKAKFPK G------------SKELVVSSFQAIVLLLFNGLKTEE---------------HMEYNYLK EATGLP-----PAELNRTLQSLACAKIR--PLTKHPKG------REINPTDTFTLNANFT ---DPKYRIKIN------------------------------TVQLKETKEENK-ETHER VAA-DRNYETQAAIVRILKAR-KRISHAELVAETIKATRS-RGTLEVSGIKKNIDRLIEK EFLEREEDN----AGWYAYIA >Pichia_guilliermondii_NZ_AAFM01000045.1| . -HLNKFCDSYLRDSSKK---------------AKKSAAP----------LTFDEFLNCVL LIFKLI-NNKDSFMVLYKRELSK--------RLLLSRS------------PNLESERSVV SSFL----KLIGD-SDMGREIDTMFS-DISLSKLDHNLTI-------------------- ----------EGVEFSALILTK-LCWPEIPGSV--------------------------- -------SDVQLLPQFRTILDEFAAKYYLSND---KFKDRVLDWSLYTLHQMEIVAQFES G------------PKELNLNLLQAMIVMLFNERDS------------------YTIEELM KETNIE-----EKLIRRVLVSLSEKYP-----------------ILVASGPTYRYNSSFK ---DKNTKLKIP------------------------------FIREKEIATMDQ-NSLRA IER-NRNQEIRAAIVKTMKQC-KNATVPQLFDAVFKLVAP-KGPISLDDFNTNLDFLVQS QYVLREATQ-------IVYVP >Pichia_guilliermondii_XM_001482055.1| . ELLSIYMDHNIKQLSKSSGQA-------KLSELNGDSAD-----------QTEQFVTKFR YFLRAI-KDKDAFEVHYANHFAR--------RFLNAKELSQGRNALSTNKLGVDLEDYVL SKLG----EETGS--SSLEKVIKMNK-DIRLSRELTQDWKNYS----------------- ----SNNRPGTSIDLELKICNV-SEWPKSMTKDYKRFSTAG------------------- ---DADSLGFVWPTQMRTIMGSFEHFWHSGK----KNDNKSLYW-SPKFGSVDMRITYPS K------------TYEINMSVYAAVIMLAFAPGLDG--------SNPFDDDRQLTYSDIK ELTGIP-----DNDLKRQLQSIAVAPRLR-LLVKIPMS------KDVKNDDTFRLNSNFK SP-SVKVKVLTVSAASSVAPAKS--------------KSASEGKEKSAKDEEME-DIQSS IVE-GRKFELNAAIVRILKSR-QQIHHNDLIAEIVKQLLN-RFQPLTIMMKQRIEDLIDK EYLRRDSEE----RNLYHYVA >Pichia_guilliermondii_XM_001487142.1| . --LARYADSYLKGS------------------SKE-SD------------TTELNPDILM IIFKFI-EDKDAFEEHYRRLLAK--------RLINSNT------------KSDELEESII QRLQ----EENSL--EYTSKMTKMFQ-DMKASEDLKNLLRAEI----------------- -----VQFDNSVKDFTPLILAQ-SMWPFTHMED--------------------------- -------YKLNLAPELMPSFDKLLALYKE------KHSGRQLKW-LWNHGKSEVKANLSR KGK---------PPFLFTVTNVQLMILLAFNKSNT------------------YTFDQLL EIVGVA-----KHTFEAHLIPFVKYK----LLEQSPSG----TAEFSKGNTTFTMVEEYK ---SKKLRVNFVSSIKS------------------------------EQKQDEV-DANKE IDE-SRKNFLSACIVRIMKAR-KQIKHNELVNEVATQALT-RFRARIIDIKKVIDYLIEK EYLRRLEND------MYEYLA >Pichia_stipitis_AAVQ01000001.1| . ELLSIYMDYHIKQKSK-------------PSPSKDVNSD-----------LTEVFISKSI EFLRFI-KDKDAFEANYANHFAK--------RFLNSKGTTQNGNA--NNKLGVDLEELIL SRLG----EEMGT--TSLAKVIKMNK-DIKLSKDTTSDWRKYT----------------- ----IKNQVPDLVELELKICNV-TDWPKSMTKDYKSFSKSD------------------- ----TGEIQFIWPKKLRTTMGEFEEFWFSGK----KNDNKSLYW-SPKFGSMDMRITYPS R------------TYEINLSTYAGIIMLLFAPQSSNADGSM---VLAFDEKKELTYNEIQ ELTGIP-----EADLKRHLQSIAVAPRLR-LLVKLPMT------KEVNDDDVFRLNESFK SP-SIKVKVLTVSAAS--------------------SVAPTRSKPKTEQEEEAE-EVQSN IAE-GRKIEVNAAIVRIMKSR-HTIRHNELIEELIKQLQN-RFQPLILLIKQRIEDLIEK EYLKRDEEE----RNLYHYVA >Pichia_stipitis_NZ_AAVQ01000001.1| . YQLCKYCDSYFKGP------------------SKKLSLP----------ETFEEFKKNVL IIFKAI-ENKRDFTEIYQKDLSK--------RLLVSRN------------TNFDHEKELA DSLL----EVIGE-SDESVGLQVMFK-DLNQSKDVYSLLIEST----------------- -----------GIEFNPLVLEK-KYWPDIPK----------------------------- -----MDTDITLPSELQLLLDQFTAKYTSSGE---RFKSQKLDWSNYTLHQLSINAEFES G------------TKELVVNLLQAVVILVFNDVNS------------------YTFVELQ QLTGMEP-----KLLKRVLGSVSSEKYA--ILSRDG--------------DIYLFNSKFT ---DKSSRIKIPLSKDK------------------------DSMKISASVSEL--DTNRI ILR-NRTDELKGAIVKVMKEF-KQLSVTELLNKAIEGVEK-RGPVTLTELKKNIDDLVDS EYLRRVDRE------TLAYIP >Pichia_stipitis_XM_001382953.1| . -------------T------------------SKE-VD------------TVDMNPENLM IVFKYL-NDKDAFEEYYRRLLAK--------RLINGNS------------KSEELEESII QRLQ----EENSI--EYTSKMTKMFS-DMKASEDLKANIKDHV----------------- -------SESIVKDFNPLILAQ-SMWPFTHMED--------------------------- -------YDLNVAPELQAPFEKVVEIYGA------KHNGRQLKW-LWNHGRAELRANLSK KGK---------APFVFTVSNLQMMILIAFNKKST------------------YTFLELH EIVGAA-----RHTFESHLLPFTKYK----LLDQSPPG----PENTGNADTTFTIVEEYK ---SKKLKVNFTSVIKN-----------------------------NEAKQEED-DANKE IDE-TRRNYLSACIVRIMKSR-KTVKHNELINEVLPQTLS-RFHAKIIDIKRVIDQLIEK QYIQRIDNN------TYEYLS >Podospora_anserina_NW_001914859.1| . EFVSLFIDDSLKRG------------------LKGKSDE-----------DAEVVLQKAI ILVRYL-SDRDLFERYYQKHLGR--------RLLHNKS------------EI-HIEKELV RRMR----AELGN--HFTAKFEGMFK-DMELSKDLSTNYKDHI----------------- --RNLGDDDRKSTELAIHVLTT-NFWPTDVMGR-----------------------GVLQ DGDA-SRSDCIFPPSIKRLQESFYKFYCQ------DRSGRVLTW-VPSTGSADIKCFFPK VPGKESGPLSKDRRYELNVSTYGMIVLMLFNDLANDES---------------LSFEEIQ LKTNIP-----IPDLTKTLTSLSVPPKFR-VLAKEPLT------KSVKPTDKFSFNAQFV ---SKQIKIRVP---------------------------VISSTSRVEGTEERK-ETERK NDQ-TRAHVVDAAIVRIMKQR-KELSHTQLTTEVISQLSG-RFKPEISLIKKRIEDLLAR EYLERMEGD----TAAYRYLA >Podospora_anserina_XM_001906682.1| . ELLAKYTDILLRKS------------------STGVEDG-----------ALEETLAQIM TVFKYI-EDKDVFQKFYSRMLAR--------RLVHSNS------------SSDDAETSMI SKLK----EACGF--EYTSKLQRMFQ-DMQISKDLNTGFKGHV----------------- ----QASIEGKNLDSTYSVLGT-GFWPLTAPGT--------------------------- --------NFNPPEEIAQDCERFTRFYKH------KHDGRKLTW-LWQLCKGDIKANYVR N---------AKMPYTFSVSVYQMAILLLFNEKLQ------------------NTYEEIA QTTQLN-----SESLDPALLVCLKAK----VLTCDSG-------AKVGPGNTYSLNLDFK ---NKKYRVNLN------------------------------VGMKSETKQEEA-ETNKT IEE-DRKLLLQSAIVRIMKAR-KKMKHQQLVSETINQIRS-RFVPKVADIKKCIEILLDK EYLERLEDD------ELGY-- >Podospora_anserina_XM_001907867.1| . ---------------------------------------------GDEDSELDTQLGHAL ELFKFI-DGKDTFEAFYKKDLGR--------RLLLGRS------------ASQDAERSMI TKLK----GECGA--NFTHNLEQMFK-DQELSRDEMTSYKTWL----------------- --AGTGKATKGGVDLTVKVLSH-SAWPTYNDVK--------------------------- ---------VTLPKEVLEQTTSFETYYQA------KHTGRKLTW-KHNMSHCIIKARFDR G------------PKELSLSAQQGSVLMLFNDVPDDT---------------PLSYSQIS QSTSLT-----GAELDRTLQSLACGKSR--VLSKAPKG------RDVSPTDTFTVNRAFA ---DPKFRVKIN------------------------------QIQLKETREENK-ETHEK VAR-DRQLETQAAIVRIMKSR-KTMGHAQLVAEVINQTKA-RGAVDPGEIKANIEKLIDK DYIEREEGN-------YVYLA >Pyrenophora_tritici-repentis_XM_001935529.1| . ELLAKYTDTLLKRSN-----------------AKMSEED-----------DMEKLLTQIM TVFKYI-EDKDVFQKFYSRMLAK--------RLVQTTS------------ASDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DMQISKDLNTAFKEWQ----------------- SNNLDESDLKTNVDASYHILGT-GFWPLNPPTT--------------------------- --------PFTPPQLIVQTYDRFSRFYNH------KHQGRKLTW-LWQLCKGEVKANYCK VAN-------LKTSPTFQVSTYQMAIMLLFNDSDT------------------VTYDEIA EATKLN-----KETLDPSLGVFIKAK----VLLLQPEN------AKHESGTTYKLNTGFK ---TKKVKMNLN------------------------------IGIKSEQKAEAE-DTHKT IEE-DRKLLIQSAIVRIMKSR-KKMKHQQLVSETIQQIKN-RFMPRVPDIKKCIDILLEK EYLERLEAD------ELGY-- >Pyrenophora_tritici-repentis_XM_001935799.1| . ------------------------------------------------DTEVNGQLDQVL DLFRFL-HGKAVFEAFYKKDLAR--------RLLMGRS------------ASADAERSML SRLK----IECGA--GFTANLEQMFR-DIELSREEMSSYKNIS----------------- ----EERNEKLGLDLNVNVLSA-SAWPTYPTVP--------------------------- ---------VILPPQIQTAISKFEAHYKI------KHSGRKLEF-KHALAHCQLKAKFPK G------------LKELVVSSFQAIVLLLFNGREDDE---------------HIDYDYLK QATGLP----ATAELNRTLQSLACAKVR--PLTKHPKG------REINETDTFTLNTSFT ---DPKYRIKVN------------------------------TVQLKETAAENK-ETHER VAA-DRNYETQAAIVRILKAR-KRISHAELVSETIKATKN-RGTLEVSGIKRNIDRLIEK EFLEREDDG------LYAYIA >Pyrenophora_tritici-repentis_XM_001941882.1| . EYISLFIDENMKKG------------------IKGKTET-----------EIDAVLEKAI VLLRYV-QDKDLLQRYYKKHLCR--------RLLMNKS------------ISNEVEKQMI SKMK----IELGN--NFTLKLEAMFK-DMTLSEEFTAGYKKHV----------------- --EGLGEKDPNRIELSINVLTS-GTWPLETMGG-------------------------VA AGKEDKRPECIYPAAVEKLKSGFKNFYDK------RHTGRQLRW-LANMGSADIKAVFPK VPQKDGSFK--ERRHDLNVSTYGMIILLLFNDVGEGEH---------------LTFEEIQ ARTKIP-----PTDLIRNLQSLAVAPKTR-ILIKEPMS------KDVKPSDRFFFNEGFQ ---GKFIKIKVG--------------------------VVS-GGNKVESDRERR-ETEKK NDD-SRCFCIEAAIVRIMKQR-KQLSHQQLMSETITQLAG-QFKPEVAMVKKRIESLLER EYIERIERTETEQTDSYRYLA >Rhizopus_oryzae_AACW02000083.1| . ELLARFCDQLLKKS------------------AKNPEED-----------ELEDVLNNVM TVFKYV-EDKDVFQKFYSKMLAK--------RLVNGTS------------ASDDAEGSMI SKLK----EACGF--EYTSKLQRMLT-DMSLSKELNEEFKSVAQNSSETPNSSGKRKKMY KACMKYLPSCILADFNILVLSA-GSWPLSAPST--------------------------- --------SFNLPDDVVQMYDKFQQFYQT------KHIGRKLNW-LFQLSKAELKTHYLK S---------SKVSYTFMVSAYQMGILLQYNNADS------------------YTYEELQ KSTGLA-----SEALNPALGILVKAK----VLLLRDGT------NVGDAGSRYVLNQDFK ---SKKVRINLN------------------------------MQMKMEQKAETD-ETHKN IEE-DRMFVMQAAIVRIMKTR-KVMKHVVLIDEVITQLQS-RFKPRVPAIKKCIDVLLEK EYIERVENQ----KDMYSYVA >Rhizopus_oryzae_AACW02000087.1| . -------------------------------------EY-----------EIEDTLDKTI MIFRYL-KNKDMFVRFYKQHLGK--------RLLLNKS------------VSDDAERGIL SKLK----RECGC--QFTNKLEGMFK-DMKLSVDMNSQFKDYL----------------- ----STTNQKFPFEFYVTTLTS-TFWPFPSTPQ--------------------------- --------VCVLPPMLLKARDSFENFYLN------RHSGRRLTW-QPQMGTADVRGHFSK S------------SHSLNVSTYAMTVLLLFNQHDT------------------LSFKEIK AMTRIA-----DADLKRVFYSLACAKYK--ILLKSSTEN-----REVRDSDSFSFNSNFT ---CHLARIKIQ----------------------------AGVSK-VETDKN----TRDK VDE-ERKYQIEAAIVRVMKDR-KKVEHNLLIVEVTRQLSF-KFIPDPLMIKKRIEALIDR EYLKRSTKD----RCIYQYLA >Saccharomyces_bayanus_AACG02000074.1| . EYISTYVDYCMKQTN-----------------DNGAEVV-----------KIKEDLLDST KLIELL-SEKDIFESTYKKQLSR--------RLLQQKS-------------VLEIEKWMV QMIK----NVLGT--FFTLKLEIMLR-DISLSSRILQAFKASS----------------- ------TSSIEYMNFVPEVLTR-TSWPFQSTNP--------------------------- -----IDDSITLPPRMSQILMGFNEYYSL------KYKERILKW-AHHLSVIEIGCQFNN G------------YYEISFSVYAGAIFLLFENYEE------------------LTLEEIH ELTHIP-----EEDVKSLVMSMSTVPKCR-ILKRSSNT----------GDTKFSVNYFFS AP-NRKVKVPII----------------------------TGPASSHKSDNSTS-QSLVD TYENENIMEVNATIVRIMKTE-GKLSHQQLLQRTTKHMER-RFHLTSSTFKRSLQLLLEK EYIQRDADD----TSCYHYL- >Saccharomyces_bayanus_AACG02000171.1| . EMLAKYSDMLLKKA------------------TKPEVAS-----------DM--SDEDII TIFKYL-TDKDAFETHYRRLFAK--------RLIHGTS------------TSAEDEESII QRLQ----AANSM--EYTGKITKMFQ-DIRLSKILEEDFAITL----------------- -KNEPDYSKSRYPDLQPFVLAE-NMWPFSYQEV--------------------------- --------EFKLPKELVPSHEKLKDSYSQ------KHNGRVLKW-LWPLCRGEIRADIGK PGR---------VPFNFTVTLFQMAILLLYNDADT------------------LTLENIQ DGTSLS-----IQHIAAAMIPFIKFK----LVQQVPPG----LDALVKPETQFKISRPYK ---ALKTNINFASGVKNDILQTLSGG----------GHDNHGNKLGNKRLTEDE-RIEKE LNT-ERQIFLEACIVRIMKAK-RNLPHTTLVNECIAQSHQ-RFNAKVSMIKRAIDSLIQK GYLQRGDDG-----ESYAYLA >Saccharomyces_bayanus_AACG02000201.1| . -----------------------------NFFERSIFRKT----------ILQSDQDS-E FVKDILPVYKDCLMELFKQ------------RIITNVS----------------QEDEML YRDQ----YQPYLS-QFFQPVELMA--DLKIKYASFLSFYENI---------------EV AVKFGKKYNEDDHSSFFPLIFDRERIPKIFQQS--------------------------- --NDELEKNFILPQEMDSTWNEFLSSFHQDNKLEDSDASKKELYPMWNLHHCDVESPYII PQGG---------HLVFELTLFQTCVLTLFNDSNR------------------LTFQSIS ERTKLG-----YKDLMLILKSFLNYK----IVTRDSEN-------SYKINENFQPDLRKV K--NGKLRVVLPR------------------------NASMQSSNTTNGKSSSA-HHEGS NSQ-WTQELLKACITRSVKGEKEGLGYDRLFETVKQQIKG----FSVGEFKDALAKLLRD KFITKDEST-----ETYKY-- >Saccharomyces_castellii_AACF01000022.1| . EMLAKYSDQLLKKS------------------SKSELVN-----------DM--SVDDIM TIFKFL-TDKDAFESHYRRLFAK--------RLIHGTS------------TSDEDEEAII QRLQ----SENSM--EYTGKITKMFQ-DVRLSKILEDDFDVIL----------------- -KKAQANKNYKLPALQPFILAE-NMWPFSYQEV--------------------------- --------DFKLPIELQESHMKLEQVYTE------KHNGRILKW-LWPLCRGELIADIGK PGR---------VPFQFTVTLFQMAILLLFNDSDV------------------LTLETIQ EGTSLS-----IQNIAAAMVPFIKFK----LIQQTPPG----LEALMKPDTEFKLARPYK ---ALKTNINFAGGVKNDILNGLISA-----------DGNSQRASGGADLTESE-KVEKE LGA-ERQIFLEACIVRIMKAK-RKLPHTMLVNECIAQSHQ-RFNAKVSMIKRAIDSLIQK GYLQRCDDG-----ESYTYLA >Saccharomyces_castellii_AACF01000051.1| . EFICFYLDSRLKWT------------------QQKKEIQ-----------SAKEDLERCV KLFKLL-SDKDLFEAFYRQQLSR--------RLLHQRS-------------SIDIERWLI KRIK----EEMGV--FFTSKLEGMLR-DIATSNDLSNNFKNAY----------------- ------ADDIGNIEYIPQILTI-TSWPFSNSPA--------------------------- -----LEEDIIFPSQLQQLKLDFEALYSK------KYNQRSLKW-DYQLSLVEIGYQFEK S------------YHELSMSVYGALILLLFEDRSS------------------LTTEMIE DLTHIP-----KQELHNQLLHMASSPKGN-ILNKLPAS------SAISPLDIFSINESFS VP-TRKYKVLTG--------------------------PSMNIPSSSSSRTEPH-NVIDN VEK-DRIAECNAAIVRIMKQN-KEMGFEELYKDAEASTAK-RFALTDRIFKKSVKSLLDK EYLRKEISD----SHILHYI- >Saccharomyces_cerevisiae_CUL8 . -----------------------------NFFERSIFRKT----------ILQSDQNS-S FIKDILPVYKDSLMELFKQ------------RIITNVS----------------QEDEMR YRDQ----YQPYLS-QFFQPVEVMA--DLRIKYASFLSFYENI---------------EA AVKFGKTYNENNSKSFFPLIFDRERIPKVFQQS--------------------------- ---NEVKKNFVLPQEMDDTWNQFLRNYHEQNKVEDSDASKKELYPMWNLHHCEVESPYII QDG---------TNLIFELTLFQTCVLTLFNESDH------------------LTLQVIS EQTKLA-----YKDLALVLKSFCNYK----ILTRDIDN-------TYSINESFKPDMKKV K--NGKLRVVLPR------------------------TASLQSSNTGGERTSSA-HHEGS NSQ-WTQELLKACITRSVKSERNGLDYDHLFETVKQQIKG----FSVGEFKDALAKLLRD KFITRDEST-----ATYKY-- >Saccharomyces_cerevisiae_NC_001139.8_CUL3| . EYLSTYVDHCMKRTK-----------------EKDAEIV-----------KIKQDLLDST KLIGLL-TEKDIFEKIYKKQLSR--------RLLQQRS-------------LVEIEKWMV QMIK----KVLGT--FFTSKLEIMLR-DISLSSEMYQAFQHST----------------- ------INSIEYLSFAPQVLTR-TSWPFQSTNP--------------------------- -----IDEGISLPPRMSQILAGFEGYYSL------KYKERVLKW-AHHLSVIEIGCQFNS G------------YYEISFSVYAGVIFLLFEDYEE------------------LTLGEIY ELTHIP-----IDDVKSLVMSMSTIPRCK-ILKKSSSS----------GNMKFSVNYFFS SP-NRKVKVPVI----------------------------ACPLPSQKSDNLAT-ASSVD TYDNEIVMELSAIIVRIMKTE-GKLSHQQLLERTTKRTQS-RLSLTPSILKRSIQLLIEK EYIQRNADD----PSYYHYLS >Saccharomyces_cerevisiae_YDL132w_Z74180.1 . EMLAKYSDILLKKA------------------TKPEVAS-----------DM--SDEDII TIFKYL-TDKDAFETHYRRLFAK--------RLIHGTS------------TSAEDEENII QRLQ----AANSM--EYTGKITKMFQ-DIRLSKILEDDFAVAL----------------- -KNEPDYSKAKYPDLQPFVLAE-NMWPFSYQEV--------------------------- --------EFKLPKELVPSHEKLKESYSQ------KHNGRILKW-LWPLCRGELKADIGK PGR---------MPFNFTVTLFQMAILLLYNDADV------------------LTLENIQ EGTSLT-----IQHIAAAMVPFIKFK----LIQQVPPG----LDALVKPETQFKLSRPYK ---ALKTNINFASGVKNDILQSLSGG----------GHDNHGNKLGNKRLTEDE-RIEKE LNT-ERQIFLEACIVRIMKAK-RNLPHTTLVNECIAQSHQ-RFNAKVSMVKRAIDSLIQK GYLQRGDDG-----ESYAYLA >Saccharomyces_kluyveri_AACE03000002.1| . EMLAKYSDQLLKKS------------------NKATET------------TSNMSIDDIM TAFKFL-TDKDAFESHYRRLFAK--------RLIHGTS------------TSDEDEEAVI QRLQ----SENSM--EYTGKITKMFQ-DIRLSKQLERDFENTV----------------- -KADPAYSKSKYADFQPFVLAE-TMWPFSYQEV--------------------------- --------DFKLPQELVPTHEGLEKLYTS------KHNGRVLKW-LWPLCRGELKANIGK PGK---------PPFQFTVTLFQMAILLLFNDVST------------------LTMEQIQ EATELS-----TPSIASSMVPFIKSK----LMQQSPPG----LEALMKPETEFKLANPYK ---ALKTKINLASGVKGDVLSGIGNN-----------------AGK-GELTESQ-KIEKE LNA-ERQIFLEACIVRIMKAK-RKLPHATLVNECIAQSHQ-RFNAKVSLIKRAIDSLISK EYLQRCDDG-----ESYEYLA >Saccharomyces_kluyveri_AACE03000008.1| . EYLTQYIDSSLRGK--------------------QKVDA-----------ALENSLGYCI SLFRLI-KDKDVFEKFYKQQLSK--------RLLQQRS-------------SLEIERMVI TKMK----QEVGV--SFTSKLEGMFR-DITISQDYNDKFAPLN----------------- ---------QHRLEYNPKVLTP-TCWPFQNTNV--------------------------- ------SQDIVLPSNLERLKLDFENFYMK------SHSGRTLRW-AYHLGSMEIGFQFGK T------------YHDLNMSVYAAIIFLLFEDHTE------------------LTMQEIN DLTHIP-----EQELVRQLLSISVAPKTR-ILKKRPMS------KNINVTDRFSINYSFT AP-STKVKVLTV------------------------LTKPEIASSIGGDDSEKK-QVMDE ISE-SRKQSANAAMVRIMKGD-KTLDHQHLIEKTTEILKD-KFRVTNTLAKQSLEYLLEK EYIQRDSDN----PMLYHYLS >Saccharomyces_kudriavzevii_AACI02000061.1| . EYISTYVDYCMKRAN-----------------EDGLEIV-----------EIKQDLLEST EIIEML-SEKDIFEKKYKKQLSR--------RLLQRKS-------------NIEIERWMV RMIK----NALGT--FFTSKLEIMLR-DVCLSFEILQAFRDSR----------------- ------TNSIEYLNFVPQVLTR-TSWPFQSTNP--------------------------- -----IDDSISLPPRMSQILASFEEYYSS------KYEERMLKW-AHHLSVIEIGCQFNN G------------YYEISFSVYAGAIFLLFEDYEE------------------LTLEEIH ELTHIP-----KEDVKFLVTSMSTMPKCK-ILKKSSDS----------GNIKFSVNYFFS SS-NRKVKVPVI----------------------------AGPISSHKSDNFAR-QTLVD TDENEKCMEINATIVRIMKEE-GRFSHQQLLEETMRQTRS-RFDLTPSVFRRSIQLLLEK EYIQRDADD----ASYY---- >Saccharomyces_kudriavzevii_AACI02000082.1| . EMLAKYSDMLLKKA------------------TKPEVAS-----------DM--SDEDII TIFKYL-TDKDAFETHYRRLFAK--------RLIHGTS------------TSAEDEENII QRLQ----AANSM--EYTGKITKMFQ-DIRLSKILEEDFAVNL----------------- -RNEPDYSKSKYPDLQPFVLAE-NMWPFSYQEV--------------------------- --------EFKLPKELASSHEKLKESYSQ------KHNGRVLKW-LWPLCRGELKADIGK PGR---------APFNFTVTLFQMAILLLYNDADV------------------LTLESIQ ESTNLN-----IQHIAAAMIPFIKFK----LIQQVPPG----LDALVKSETQFKISRPYK ---ALKTNINFASGVKNDILQSLSGG----------GHDNHGSKLGNKRLTEDE-RIEKE LNT-ERQIFLEACIVRIMKAK-RNLPHTTLVNECIAQSHQ-RFNAKVSMIKRAIDSLIQK GYLQRGDDG-----ESYAYLA >Saccharomyces_mikatae_AABZ01000006.1| . EYFSTYVDYCMKRAK-----------------DNDVEMV-----------TIKQDLLDST RLIKLL-SKKDTFEKTYRKQLSR--------RLLQQRS-------------VVEIEKWTV QMIK----KVLGA--FFTSKLEIMLR-DVSLSSEILQGFKDSM----------------- ------TNSIEYLSFVPQVLTR-ISWPFQSFNP--------------------------- -----IDEIVSLPPRMSQVLAGFEGHYSS------RYKERVLKW-AHHLSVIEIGCQFNT G------------YYEISFSVYAGAIFLLFEDYEE------------------LTLKEIY ELTHIP-----EEYVKSLVISMSTVPRCK-ILKKSSNS----------GSTKFSVNYFFS SS-NRKVKVPVI----------------------------AGPVLSHKSENLAN-HNLVD TYENEIIMVLSATIVRVMKTE-GRLSHQRLLEIVTKQTLP-LFDVTPSIFKRGIQLLLEK EYIQRDADD----TSYYHYLS >Saccharomyces_mikatae_AABZ01000126.1| . -----------------------------NFFERSIFRKT----------ILQSDQNS-P FIKDILPVYKDGLIELFKE------------RIVTNVS----------------REDEIQ YRDQ----YQPYKS-QFFQATEVMA--DLRIKYASFLSFYENI---------------EA AVKFGKEYNENNNNLFFPLIFDRERIPKGFQQP--------------------------- --NNELKNNFILPQEMDDAWNKFLCNYHK-NKVENSDTSMKELCPMWNLHHCEVESTYVI PDG---------CSLTFELTLFQTCVLILFNECDH------------------LTLQVIA ERTNLA-----HKDLLPILKSFLNYK----ILIKDNNN-------TYCINENFKPDLKKV K--NGKLRVVLPR------------------------NTSMQSSNTGDSRSSSA-HHEGS NYQ-WTQELLRACITRSIKSERDGLSYDHLFETVKRQIKG----FSVGEFKDALAELLRD KFITKDEST-----DTYKY-- >Saccharomyces_mikatae_AACH01000135.1| . EMLAKYSDILLKKA------------------TKPEVTS-----------DM--SDEDII TIFKYL-TDKDAFETHYRRLFAK--------RLIHGTS------------TSAEDEENII QRLQ----AANSM--EYTGKITKMFQ-DIRLSKILEEDFAVTL----------------- -KNEPDYSKSRYPDLQPFVLAE-NMWPFSYQEV--------------------------- --------EFKLPKELVPSHEKLKESYSQ------KHNGRILKW-LWPLCRGELKADIGK PGR---------VPFNFTVTLFQMAILLLYNDADI------------------LSLENIQ EGTNLS-----IQHIAAAMIPFIKFK----LIQQVPPG----LDALVKSETHFKISRPYK ---ALKTNINFASGVKNDILQSLSGG----------GHDNHSSKLGNKRLTEDE-RIEKE LNT-ERQIFLEACIVRIMKAK-RNLPHTTLVNECIAQSHQ-RFNAKVSMVKRAIDSLIQK GYLQRGDDG-----ESYAYLA >Saccharomyces_paradoxus_AABY01000070.1| . -----------------------------NFFERSIFRKT----------ILQSDQNS-P FIKDILPIYKDSLMELFKE------------RIITNVS----------------QEDEMR YRDQ----YQPYLS-QFFQPVEVIA--DLRIKYASFLSFYENI---------------EA AVKFGKKYNENNNNSFFPLIFDRERIPKVFQQS--------------------------- ---NEVKKNFILPQEMDDTWNKFLCKYHQENKVQDSDASKKELYPMWNLHHCEVESPFIT PDG---------TNLIFELTLFQTCVLVLFNESDH------------------LTLQIIS ERTKLA-----YKDLTLILKSFLNYK----ILTRDIDN-------LYSMNESFKPDMRKV K--NGKLRVVLPR------------------------NASLQNSNASSARSSSA-HHEGS NSQ-WTQELLKACITRSVKSESNGLDYEHLFETVKQQIKG----FSVGEFKDALAKLLRD KFITKDEST-----GTYKY-- >Saccharomyces_paradoxus_AABY01000121.1| . EMLAKYSDILLKKA------------------TKPEVAS-----------DM--SDEDII TIFKYL-TDKDAFETHYRRLFAK--------RLIHGTS------------TSAEDEENII QRLQ----AANSM--EYTGKITKMFQ-DIRLSKILEEDFAVAL----------------- -KNEPDYSKSKYPDLQPFVLAE-NMWPFSYQEV--------------------------- --------EFKLPKELTPSHEKLKESYSQ------KHNGRILKW-LWPLCRGELKADIGK PGR---------MPFNFTVTLFQMAILLLYNDADV------------------LTLENIQ EGTNLS-----IQHIAAAMVPFIKFK----LIQQVPPG----LDALVKPETQFKLSRPYK ---ALKTNINFASGVKNDILQSLSGG----------GHDNHGNKVGNKRLTEDE-RIEKE LNT-ERQIFLEACIVRIMKAK-RNLPHTTLVNECIAQSHQ-RFNAKVSMVKRAIDSLIQK GYLQRGDDG-----ESYAYLA >Saccharomyces_paradoxus_AABY01000163.1| . EYFSTYVDYCMKRAK-----------------ENDAEVV-----------KIKQELLDST KLIGLL-TEKDIFEKTYKKQLSR--------RLLQQRS-------------LVEIEKWMV QMIK----KVLGT--FFTSKMEIMLR-DISLSSEIFQAFKNST----------------- ------ANSIEYLSFVPQVLTR-TSWPFQSTNP--------------------------- -----IDETISLPPRMSQILAAFEGYYSS------KYKERVLKW-AHHLSVIEIGCQFNS G------------YYEISFSVYAGVIFLLFEDYEE------------------LTLGEIY ELTHIP-----EGDVNSLVLSMSTIPRCK-ILKKSSNS----------GIIKFSVNYFFS SP-NRKVKVPVI----------------------------AGPILSHKSDNLAT-PSSVD TYDNEIIMELNATIVRIMKTE-GKLNHQQLLERATKQSRP-RFSLTPSLFKRSIQLLVEK EYIQRDADD----ASYYHYLS >Schizosaccharomyces_japonicus_XM_002172756.1| . ELLAKYIDHLMRST------------------KSVVGNN-----------TFDNVCAELL DIFRYL-PNKDVFEAFYKRDVAK--------RLLLNKS------------ANTDNERKLL EMLK----EKCGS--TFTHSLEGMFK-DVDFSKDFSKSFKESK----------------- ------FGRSLHYDLFVNVLSL-AYWPTYPDTT--------------------------- ---------ITLPPELETDLDIFKNFYLS------QQTARRLAW-RPALCYCLLKAEFPS G------------SKELSVSLFQACVLLLFNDVGDEG----------------LSYVDIQ KRTQLN-----DNDLTRTLQSLCCAHVRP-LLMQPKS-------RRITKEHRFFYNQHFT ---NPHFRIKIN------------------------------QIQLRESKEEKA-SVQEE VVR-DRQFELQACVVRLMKAN-KTMTYNQLVRQTMDYLQI-RGKPDLSEVKKGIEKLIEK EYIERTDDT------NLAYV- >Schizosaccharomyces_japonicus_XM_002173761.1| . ELLARYTDAVLRRN------------------SKTGDTE-----------DIEQVLSSVM IVFRYV-EDKDVFQKFYAKFLAK--------RLVNGTS------------TSEDSESSML SKLK----EACGF--EYTNKLQRMIQ-DIGLSSDLTDAFHAQQ----------------- ------PSKLSPIDFNILVLST-SSWPLSSSST--------------------------- --------TFRLPNELAELHDAFQNFYQN------KHSGRKLNW-LMHLSKGEMKAKFGD S---------SSTTYILQVSTYQMGVLLLYNAADS------------------YTFAELQ QNTELS-----ATYLSGILRIFLRAK----ILVQQGNN------KLDDPSTVFALNRQFR ---SRRIRLPLN------------------------------LPIKTEQKQESA-ETQKT IKE-DRKLLLQSAIVRIMKAR-KTLKHVVLVKETIDQIKS-RFKPEVADIKRCIDILIEK EYLERQGRD------EYVY-- >Schizosaccharomyces_japonicus_XM_002175411.1| . EYISLFIDDYLKKG------------------LRGQSEA-----------EVEQMLQKSV TLFRFV-SEKDVFEKYYKIHLAK--------RLLNNRL------------SSEDVELELI SRLK----LEAGN--VFTSKMEGMLT-DMRLSQDANKEYKDYL----------------- ----TENNISSAFDLNVSVLAS-SFWPVEMQPE--------------------------- ------KLKCNFPQELEEAKDVFTSFYLS------KHSGRQLAW-YPTMGTADVRVAFKN R------------KHDLNVSTVALMILLHFEDVEATEP---------------ILYETLR DRIQIE-----ESDLKRNLQSLACAKYK--ILLKEPKG------RNINPGDKFYFNDAFT ---SNLARIKIA----------------------------TVASARVENDHERK-ETLEK IDE-SRKHQVEACIVRVMKDR-KTLDHNQLIAEVSRQLST-RFMPNPMMIKRRIEALIER EYLQRNADN----SRVYEYLA >Schizosaccharomyces_octosporus_2_ABHY02000001.1| . -----YIDYLLRHG------------------EQVTNGT-----------PLQQIFETLL DIFRYV-ASKDVFEAFYKRDIAK--------RLLLNKS------------ASSQNERMLL EMLK----KTCGS--QFTHALEGMFK-DINLSKEFSSSFQQSK----------------- ------LSKNLHRDLYVNVLSQ-AYWPAYPEGH--------------------------- ---------VRLPEDMQEDLQQFEKFYLA------KQTSKRIRW-LPSLGHCLVKARFPL G------------NKELSISLFQACVLLEFNKCAPGE---------------GLTYRDLQ KTTELT-----DADLTRTLQSLSCVRVRP-LVMVPKG-------KVPKPDTMFYVNEKFT ---DKLYRIKIN------------------------------QIYLKDERQESE-EVQEQ VLQ-DRQFELQAAVVRIMKQN-ERVSHDELVQKTIEVCKN-RGIPEISDIKSTIEKLLNK EYLERQDGE-------YVYV- >Schizosaccharomyces_octosporus_ABHY02000001.1| . ELLAKYSDSVLRKN------------------SKTVEVD-----------DIENILTSII IIFRYV-EDKDVFQNFYTKLLAK--------RLVNGMS------------NSQDAEAGML SKLK----EVCGF--EYTSKLQRMFQ-DISLSQELTESFHQLP----------------- ------EMQKSPIDFYAMVLGT-SFWPLTASSS--------------------------- --------NFHIPSELKSLYERFEGYYNT------CHNGRKLSW-LFHLSKGEIKARINP N---------SSTTYVFQVSTFQMAVLLLYNQRTS------------------YKYDELL ELTGLN-----QDILTGILNIFLRAK----VLLLEEGK------NLGELDSVYTLNMNFK ---MKKIRVQLN------------------------------LPIKSEQKQEVV-ETQKT IEE-DRKLLLQSAIVRIMKAR-RTLKHVVLVKETIDQIKS-RFAPQVSDIKRCIDMLIEK EYLERQGRD------EYVY-- >Schizosaccharomyces_pombe_NM_001018350.1_cul3| . EYISLFIDDNLKKD------------------ARKAIEG-----------SIEATLQNSV TLFRFI-SEKDVFEKYYKTHLAK--------RLLNNRS------------ISSDAELGMI SRLK----QEAGN--VFTQKLEGMFN-DMNLSQELLQEYKHNS----------------- ----ALQSAKPALDLNVSILAS-TFWPIDLSPH--------------------------- ------KIKCNFPKVLLAQIDQFTDFYLS------KHTGRKLLW-YPSMGSADVRVNFKD R------------KYDLNVSTIASVILLLFQDLKENQC---------------LIFEEIL EKTNIE-----VGDLKRNLQSLACAKYK--ILLKDPKG------REVNAGDKFYFNENFV ---SNLARIKIS----------------------------TVAQTRVEDDSERK-RTLEK VDE-SRKHQADACIVRVMKDR-KVCEHNQLMAEVTRQLNP-RFHPSPMMIKRRIEALIER EYLQRQADN----GRIYEYLA >Schizosaccharomyces_pombe_NM_001019682.1 . ELLAKYADSILRKS------------------NKNVDID-----------DVEDCLSSII IIFRYV-EDKDVFQNFYTKLLAK--------RLVNGTS------------NSQDAESSML SKLK----EVCGF--EYTSKLQRMFQ-DISLSQEITEAFWQLP----------------- ------QSRAGNIDFSALVLGT-SFWPLSPNNV--------------------------- --------NFHLPEELVPLYEGFQNYYYS------CHNGRKLSW-LFHLSKGEIKARINP Q---------TNVTYVFQVSTYQMGVLLLYNHRDS------------------YTYEELA KITGLS-----TDFLTGILNIFLKAK----VLLLGDND------KLGDPNSTYKINENFR ---MKKIRVQLN------------------------------LPIRSEQKQESL-ETHKT IEE-DRKLLLQSAIVRIMKAR-RTLKHVVLVKETIDQIKS-RFTPKVSDIKQCIDMLIEK EYLERQGRD------EYIYLA >Schizosaccharomyces_pombe_Z99260.2 . RLIAKYIDYLLRVG------------------EQASGGK-----------PLKEVFSEIL DLFRYI-ASKDIFEAYYKLDIAK--------RLLLNKS------------ASAQNELMLL DMLK----KTCGS--QFTHSLEGMFR-DVNISKEFTSSFRHSK----------------- ------AAHNLHRDLYVNVLSQ-AYWPSYPESH--------------------------- ---------IRLPDDMQQDLDCFEKFYLS------KQVGKKISW-YASLGHCIVKARFPL G------------NKELSISLFQACVLLQFNNCLGGE---------------GISYQDLK KSTELS-----DIDLTRTLQSLSCARIRP-LVMVPKS-------KKPSPDTMFYVNEKFT ---DKLYRVKIN------------------------------QIYLKEERQENS-DVQEQ VVR-DRQFELQASIVRVMKQK-EKMKHDDLVQYVINNVKD-RGIPLVSDVKTAIEKLLEK EYLEREDND------IYTYVT >Sclerotinia_sclerotiorum_NZ_AAGT01000331.1| . ELLAKYADSLLKKS------------------ASGAEES-----------DIENSLTQIM TVFKYI-EDKDVFQKFYSRMLAR--------RLVHTSS------------SSDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DIQISKDLNSGFKEFE----------------- -SGIFTGGEDKPIDASYSILGT-GMWPLNPPNT--------------------------- --------DFTPPMEISKAYERFQNFYNQ------KHSGRKLTW-LWQLCKGEIKANYCK N---------QKTPYTFQVSTYQMAILLLFNESDK------------------NSYEDLA KATQLQ-----ADVLDPILGIFLKSK----VLTMTPAD------DKPGPGKTFHLNYDFK ---SKKIRVNLN------------------------------IGIKSEQKQEVD-ETHKT IEE-DRKLLMQSAIVRIMKAR-KRMKHSQLVGETINQIRS-RFSPKIPDIKKCIDILLEK EYLERLDDD------ELGY-- >Sclerotinia_sclerotiorum_XM_001585695.1| . EFVSLFIDDNLKRG------------------IKGKTEL-----------EIDEVLDKAT TLLRYI-QDKDMFERYYKKHLAK--------RLLLNKS------------ESTDVEKQMI SRMK----LEIGN--SFTTKLEGMFK-DITMSEELSSNYRNHI----------------- --NNLGDKDKNQIELSAIVLST-NCWPTEIIGG------------------------IPS QEEG-PRQSCNWPPQLQKLQDSFKAFYLK------DRNGRMLTW-LGNLGNADIRCNFPA IPGETGAKGR-ERKYELNVNTHGMIILMLFNDLQDGQE---------------LLYEEIQ QRLNIT-----DKDLPRALMQLSGPLKSR-VLLKKPGKPN----ELPKMGDTFTLNSSFV ---SKTVKIKVQ--------------------------PIGGQSSKVEGADERR-QTEER NDE-HRGSVMDTVIVRIMKAR-KECPHQQLVAEVISQLSQ-RFQPNINMMKRRIESLIER EYLERIEDAN---IPTY---- >Sclerotinia_sclerotiorum_XM_001595088.1| . ---------------------------------------------GDEDAELDRQLEQGL ELFRFI-EGKDVFEAFYKRDLAR--------RLLMARS------------ASQDAERNML AKLR----GECGN--SFTHNLESMFK-DQEISRDEMISYKQSL----------------- -----SNTSKTTLDLQVSVLSS-AAWPTYPDIE--------------------------- ---------VNLPAEVAKHIEKYDRHYKH------KHSGRRLTW-KHSLAHSIVRATFNK G------------VKELLVSGFQAVVLVLFNELEDGG---------------HLSYTDIS KATGLV-----DGELKRTLQSLACAKVR--PLTKYPKG------KEISETDTFTINLNFS ---DPKFRIKIN------------------------------QIQLKETKEENK-ETHEK VIQ-DRSFETQAAIVRIMKSR-KTMTHQNLVAEVINQTKG-RGAVEPAEIKKHIEKLIEK DYIEREDGG------IYTYLA >Talaromyces_stipitatus_ABAS01000003.1| . ELLARYTDSLLKKG------------------SKATEES-----------ELEEMLTQIM TVFKYI-EDKDVFQKFYSKSLAK--------RLVHIIS------------VSEDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DIQISKDLNASYKDWQ----------------- EKVHDEEDRKKMVDPHYQVLGT-GFWPLNAPTT--------------------------- --------EFIPPTEIVKTAERFQHFYFD------KHSGRKLTW-LWQLCRGEIKANYIK N---------AKVPYTFQVSTYQMGILLLYNEHDS------------------LDYDEIQ KATKLA-----NEILEPNITLLLKAK----VLLANSEG------SKPAPGVSFSLNYNFK ---HKKVKVNLN------------------------------LTIKSEQKTEAD-DTHKT IEE-DRKLLLQSAIVRIMKSR-KKMKHVQLVQEVIQQVKA-RFPPKIPDIKKNIEALMEK DYIERLDND------ELAY-- >Trichoderma_atroviride_ABDG01000023.1| . EYVSLFIDDSLKRG------------------IRGKTED-----------EVDAILEKAV VLIRYL-ADKDLFQTYYQRHLAR--------RLLHGKS------------ESHDVEKQII LRMK----QEMGQ--QFTSKFEGMFR-DLVTSAELTSTYRDHI----------------- --RNLGD-ESHTVELNVNVLTT-NYWPQEVMGR------------------------SVQ LDDA-PRMQCTYPQEVKRLQASFEQFYLT------NRNGRKLTW-IGTTGSADIKCTFPA IEGKSGPLAR-ERRYEINVPTFGMIVLMLFNDLKDGES---------------LSFEEIQ AKTSIS-----TVDLTRALMAISVAPRSR-VLAKDPPT------KTIKPGDKFSFNASFQ ---SKTIRIKAP---------------------------IINAISKVEDKEERK-STEEK NNQ-TRAHIVDAAIVRIMKAR-KELSHSQLVSEVLSQLVG-RFKPEVTLIKKRIEDLIVR EYLERPDEDG--APSMYRYMA >Trichoderma_atroviride_ABDG01000112.1| . ------------------------------------------------DAELDRQLDQAL ELFRFI-EGKDAFEAFYKKDLAR--------RLLMGRS------------ASQDAERNML TKLR----GECGS--NFTHNLEQMFK-DQELAKDEMEAYKEWC----------------- ---EGNPDRIGKVDLQVMILSA-AAWPTYPDVR--------------------------- ---------LNLPDEVAKRTEQFERHYKN------KHTGRVLTW-KHSLAHCSVKATFPK G------------AKELLVSAFQAAVLLLFNDVAADG---------------FLAYEQIS AATGLQ-----GGDLDRTLQSLACGKAR--VLTKHPKG------RDVNPTDTFTFNKAFT ---DPKYRVKIN------------------------------QIQLKETKEENK-ATHEK IAQ-DRRFETQAAIVRIMKSR-KTMGHAELVAEVINLTKS-RGSVEPAAIKKEIESLIEK DYLEREENS-------YTYLA >Trichoderma_reesei_AAIL01000778.1| . ------------------------------------------------DAELDRQLDQAL ELFRFI-EGKDAFEAFYKKDLAR--------RLLMGRS------------ASQDAERNML TKLR----GECGS--NFTHNLEQMFK-DQELAKDEMEAYKEWC----------------- ---QGHPDRVGKVDLQVMILSA-AAWPTYPDVR--------------------------- ---------LNLPDDVATRIEQFDRHYKS------KHTGRVLTW-KHSLAHCSIKATFPK G------------AKELLVSAFQAAVLLLFNDVPADG---------------FLSYEQIS AATGLQ-----GGDLDRTLQSLACGKAR--VLTKHPKG------RDVDPKDTFTFNKAFT ---DPKYRVKIN------------------------------QIQLKETKEENK-ATHEK IAQ-DRRFETQAAIVRIMKSR-KTMGHAELVAEVINLTKK-RGSVEPAAIKKEIE----- --------------------- >Trichoderma_virens_ABDF01000147.1| . EYVSLFIDDSLKRG------------------IRGKTEA-----------EVDAILEKAI VLIRYL-LDKDIFQTYYQRHLAR--------RLLHGKS------------ESHDVEKQII SRMK----QEMGQ--QFTSKFEGMFR-DLVTSSELTSTYRDHI----------------- --RKL-DPEGHTIDLNVNVLTT-NYWPSEVMGR------------------------SAQ LGEA-PRMGCTYPPEVKRLQASFEQFYLT------NRNGRKLTW-IGTTGSADIKCVFPA IEGKSGPLAR-ERRYEINVPTYGMVVLLLFNDLKEGES---------------LSFEEIQ AKTNMS-----TADLTRALMAIAVAPKSR-VLAKDPAT------KSIKPTDRFSFNASFQ ---SKTIRIKAP---------------------------IISAVSKVEDKEERK-TTEEK NNQ-TRAHIVDAAIVRIMKAR-KELNHSQLVSEVLSQLVG-RFKPEVSLIKRRIEDLIVR EYLERPDEDG--APSMYRYVA >Trichoderma_virens_ABDF01000220.1| . ------------------------------------------------DAELDRQLDQAL ELFRFI-EGKDAFEAFYKKDLAR--------RLLMGRS------------ASQDAERNML TKLR----GECGS--NFTHNLEQMFK-DQELAKDEMEGYKEWC----------------- ---QGSPDRIGKVDLQVMILSA-AAWPTYPDVR--------------------------- ---------LNLPEEVATRIDQFDKHYKN------KHTGRVLTW-KHSLAHCAIKATFPK G------------AKELLVSAFQAAVLLLFNDVAADGF---------------LAYEQIS AATGLQ-----GGDLDRTLQSLACGKAR--VLTKHPKG------RDVNPTDTFTFNKAFT ---DPKYRVKIN------------------------------QIQLKETKEENK-ATHEK IAQ-DRRFETQAAIVRIMKSR-KTMGHAELVAEVINLTKQ-RGSVEPAAIKKEIESLIEK DYLEREENS-------YTYLA >Ustilago_maydis_AACP01000133.1| . EFISLFIDENLKKG------------------LKGKTEV-----------EVEEMLRKTI SVFRFL-HEKDTFERYYKQHLAK--------RLLQGRS------------VSDDAERGMM AKLK----IESGH--GYVAKLQGMLN-DMKTSEETVEEFNRSV----------------- ----KNSARGMRFGVSVNVLTS-TNWPISAQPP--------------------------- --------SCTMPEMLMEARRRFEEFYQS------KHNGRVLTW-HANLGNADIRVAFNS R------------THEINVSTFALVVLLLFEEGSGNEV---------------LSYDEIA RATNMG-----DVDLQRTLQSLACGKFR--ILNKIPKG------REVEKEDKFCFNSGFT ---CPLARFKIQ----------------------------QVAAR-VETSKERL-VTNAK LDE-QRSFLIEASIVRIMKNR-KHLAHSDLVQQIITQLSP-RFHPSLPAIKKRIESLIER EYLERTDSA----RNMYTYLA >Ustilago_maydis_XM_398702.1 . ELLAKHADALLKKS------------------NKATAEN-----------SLEEALADVM VVFKYI-EDKDVFQKFYSKMLAK--------RLVNFAS------------ASDDAEASMI SRLK----EVCGV--EYTKKLQTMFT-DMGLSKELNDHFKDTM----------------- --ANHYDKTELDVDFYSLVLGR-SSWPLQAPTT--------------------------- --------EFSIPTELLPTYERFQRYYSV------KHQGRKLIW-LWQLSKNEVKTNYLS Q------------KLQFQTSTFQTAVLLQFNTNDS------------------LTKTQLQ QATGLN-----DATIKPVLGMLSKAK----VLVTSSSD-----------PEAYELNANFK ---SKKLRVNLN------------------------------LPVKAEQKAESN-DVLKT IDE-DRRLLLQATIVRVMKSR-KQLKHQALIQETVAQVSG-RFNPRVSDIKKAIDQLIDK EYLERLEGS----KDTYSYLA >Ustilago_maydis_XM_403178.1 . ELIAKYLDAKLRSG------------------NKTMSDL-----------ELENSLDEAL ILFRYT-QAKDMFEEFYKRHFAK--------RLLLNRS------------ASSDAERSML LKLK----AECGP--EFTAKLETMIK-DVEVSKDLMDEYVRFA----------------A KQRKDEPSPKDDFDLSVSVLTQ-AHWPTYPNID--------------------------- ---------VALPVELAAAAERFAAFYQN------RNSGRRLHW-QHSLGTLTMTAKFEK A-----------GVKELHVSTFQAIILMLFNTLEPGQ---------------KLSYADIR THTGLN-----DQELKRTLQSLACGLIPTRVLRKHPQG------KEVNDDDHFTFNDNFK ---NDRHRIRIN------------------------------QIQMKETAEEQK-STEQR VFL-DRELILQAATVRVLKAK-KTIKHSELITEVVDQIKN-RFTVDVAEIKKEFEILIEK EYMERVEGQ----RGMYRYLA >Vanderwaltozyma_polyspora_XM_001645144.1| . ELVTIYLDSYLKNL------------------EDNNAIS-----------EAKNHLDQYV RIFITL-PEKDVFESQYRKFLSR--------RLLQQRS-------------IFNLEKWLV QRFK----EELGT--FFTSKMEGMLR-DINNSKDLLRSFKNSN----------------- --SNTNSLINLNLNYNPEILTA-ISWPFNNNNQ--------------------------- -----DNNEIILPVKLKEVQEDFEKFYKK------KYSQRTLTW-SPTLSMIEVSYQFDK T------------QHDLILPFYSAIIFLLFEEYDQ------------------LSLEKIS ELTNIP-----NQELIRHLLSLSIAPRAK-LLTKEPPT------RNISPNDKFSINKSFT AS-TRYIKIQTV-----------------------------NLVPNSSNNASNN-NNNDE LLQRERLQEVNASVIREMKSN-KILTINELESTITNIVKD-RFQLQHNLFIKSIDYLIDK EYLQKDIDD----TELLHYL- >Vanderwaltozyma_polyspora_XM_001646854.1| . EMLARYSDQLLKKS------------------TKPEISH-----------DM--SVDDIM MIFKFL-TDKDAFESHYRRLFAK--------RLIHGTS------------TSDTDEESVI QRLQ----SENSM--EYTGKIAKMFQ-DVRLSKLLEDEFESYA----------------- -KNLPDFSRERYPELEPFVLAE-TMWPFSYQEV--------------------------- --------GFNLPPDLKPSYEKLEELYTT------KHNGRILKW-LFPLCRGELKANIGK PGR---------PPFNFTVTLFQMSILLLFNDEKLSENPV-------------LTLEEIQ EGTNLS-----VNNIAASMIPFIKYK----LIQQVPPG----LEALIKPDTQFKLSTPYK ---ALKSRINFASGVKNDVLNLIQASNSTNNNNSNSNSAQSQGSQLDDGISENE-KIEKE LNK-ERQIFLEACIVRIMKAK-RKSPHTTLVNECIAQSHQ-RFNAKVSMIKKAIDSLIQK EYLQRCDDG-----ESYQYLA >Verticillium_dahliae_ABJE01000879.1| . ------------------------------------------------DAELDRQLDAAL ELFRFI-EGKDAFEAFYKKDLAR--------RLLMGRS------------ASEDAERNML RKLR----DECGA--NFTRNLEQMFK-DQELAKEEMQHYKQWS----------------- ----EGTNAEQQVDLQVMVISA-ASWPTYPDTK--------------------------- ---------LNLPEGAAVEIERFERWYNQ------KHDGRKLSW-PHSLANCTVKAIFPR G------------TKELLVSAFQAVVLVLFNEVDLEG---------------FLSFGQIS TATGLA-----GPELQRTLQSLACGKVR--VLSKHPKG------RDVSETDTFTINKAFT ---DPKLRIKIN------------------------------QIQLKETKEENK-ATHER IAE-DRKFETQAAIVRVMKAR-KTIGHSELVAEVINFTRK-RGPVDAASIKKLIETYVSR --------------------- >Verticillium_dahliae_ABJE01001341.1| . ELLAKYTDVLLRKS------------------GTGIEET-----------ELENTLTQIM IVFKYI-EDKDVFQKFYSRMLAR--------RLVHSNS------------SSDDAETSMI SKLK----EACGF--EYTNKLQRMFQ-DMQISKDLNNSYREHC----------------- ---NGLENAKNILDSQYSILGT-GFWPLQAPNT--------------------------- --------NFTPPAEINEETERFSRFYKN------KHEGRKLTW-LWQLCKGELKAGYCK A---------SKTPYTFQVSIYQMAVLLLFNEKDS------------------HSYDDIA GATLLS-----NEVLDQALAILLKAK----VLLIFPE-------GKPESGKELRLNYDFK ---SKKIRVNLN------------------------------LGGAKEAKQEEV-ETNKT IEE-DRKLLIQSAIVRIMKAR-KKMKHMQLVSETINQIKT-RFVPKVPDIKKCIEILLDK EYLERLEED------ELGY-- BIKONTS – FIGURE 4 >Ostreococcus_tauri_CR954203.4| . EYMS--LYLDQVLRKS------------------PKEMSQN---ELENIFNRSMGLFRLF -HEKDVFEGYYRLHLSRRLLNKRS----------------ASDDNELAFIARLK------ ----------DECGYTFTSKMESMFS---DMLTSGDLNREFHETK--------------- ----------------------------------FASGTPLDASFSVLTT-------GVW PMRMQKS---HPFLPSECEAACAAFEAFYLG-------RHAGRKIYW-QSAMGQAEIKFT VASG-------------------------------------------------------- ------------------------------------------------EYDLITSTRHMC VLMLFNRHNV-----------------------LTTAQISQLTLMH-----DDELKACLQ ALSCVKGKN-VLKRTPDG------------------------------------------ --------KEVLPTDTFEVNEDFS----SKSSRVKIS----------------------- --TISSRRENDHERA-SKSRQLSD-DRKYQVEATIVRVMKTKKRLSHNDIVVEVTAQVKN ---RFMPTPADIKKYIEGLVEKDYIRRDPNDRRLYEYVA >Plasmodium_berghei_XM_670701.1 . KLFK--MYQDVGKC-------------------------------IMSIVTIVLSLFKYI -SDKEKFEKYYRIFMCKRLINDNS----------------FNIVLDIKVFKTLK------ ----------KECGQQFTKKIESILK---DMKITSKIVKRFYNEM--------------- ------------------------------PHNSIKLLKKKKYFVNIIFN-------ETW DYNKLEN---SVIYPESVKMCNDFFLKYYKR-------YNKSKNITF-LPLFGLCTLKVN FSRITKKKEYSRWQAG---------------ILQLLEKNDSNKNSAKSESDNDIF----- ------------------------------------------CKKKKKKIYITVTIIQAL CLLQFNKNLE-----------------------YTINELCDMTGIS-----IDNILCYLK SIYTDGETQ-ILIYDEIN------------------------------------------ --------------KKFKVNSEFK----SKKKHLVVDYADTTY----------------- -------RDNTNIPA-LTQENMENEDISLHIDAAIVKFLKVEGKASQMNICEYIKKKK-- ----NISSNEQITNRISSLVN------------------ >Plasmodium_yoelii_XM_725006.1 . KLFT--MYQDVGKC-------------------------------IMSIVTIVLSLFKYI -SDKEKFEKYYRIFMCKRLINDNS----------------FNIVLDIKVFKTLK------ ----------KECGQQFTKKIESILK---DMKITSKIVKRFYNEM--------------- ------------------------------PHNSIKLLKKKKYFVNIIFN-------EIW DYNKLEN---SVIYPESVKMCNDYFLKYYKR-------YNKSKNITF-LPLFGLCTLKVN FSRITKKKEYSRWQAD---------------ILQLLEKNDSNKNSVKSESDNNLFC---- ------------------------------------------KKKKKKKIYITVTIIQAL CLLQFNKNLE-----------------------YTINELSDMTGIS-----IDNILCYLK SIYSDGETQ-ILIYDEIN------------------------------------------ --------------KIFKVNSQFK----SKKKHLVVDYADTTY----------------- -------KDNTNIPA-LTQENMENEDISLHIDAAIVKFLKVEGKASQMNICEYIKKKM-- ----NISSNEQITNRVSSLVNREFIFF-QND--LYHYEL >Plasmodium_falciparum_NC_004327.1| . KLFK--KYHIIGKY-------------------------------IMNMITVILSLFRYV -SDKEKFEKYYRTYMCKRLINDSS----------------FNIILDVKVFKTLK------ ----------KECGAQFTKKIEIILK---DMKFTSKTLMKFYKEL--------------- ------------------------------PNNVNHFLKRKKYAVNIIFN-------ESW EYVNTEN---NVIYPPMIKMCNEAFFLFYQK-------YNKSKNIKF-LPLLGLCTLRVH FKNFKEEGSFDLGKRDDNNDEKRDDNNDEKRDHNNIEKRDDNNIEKRDDNNIEKRDDNNI EKRDDNNDEKRDENNDKKRDENNNYSDDNDDDLNNEDSSSTYNKKGKKKIYITVTILQAL VLLLFNKKNE-----------------------YHINEIKELTGIS-----TENIIRYLK TIYTIGETH-ILIYDKAN------------------------------------------ --------------EILKLNFSFR----SKKKFLIVNYNDVLY----------------- ------KDDMGPTTS-LLNEDNEIEDKTLHIDAAIVKFLKTNGKSSERKICSFIKDKM-- ----DISSNEQIKNRISSLLSREFIFF-KNN--NYHYEL >Plasmodium_knowlesi_AM910993.1| . KLFK--KYHDVGKY-------------------------------IINTVTIILSLFKYL -SDKEKFEKYYRTYMCKRLINDKN----------------FNIVLDVKVFKTLK------ ----------KECGPQFTKKIETILK---DMKYSCKGMQDFYKEIS-------------- -------------------------------HDGIKLLKKKKYSVNVIYN-------DVW EHNKLEG---GIIYPEAIRLCNDYFCKYYAL-------VNKAKNIKF-LPLYGLCTLKVD FGKIEEKKYRTLSSSSCENAEHSESDNSAG------------------------------ ----------KHLSCGERDTKGAKTNGRNGFQKNKHNVHEEENFKKRRRFLFTVTTLQAT VLLLFNKRPQ-----------------------YSIGELTDLTGFS-----RDHLIEYLK GIYTGYETN-ILIYDEAH------------------------------------------ --------------ENFQLNVNFQ----TDNKYLVVNYSDQTY----------------- -------KDNTAIPA-LTQDDKELEDRTLHIDASIVKFLKTCGKASERDICAHTRQKV-- ----NNCTNEQIKSRLASLISREFIFL-QNN--IYYFEL >Plasmodium_vivax_XM_001616256.1| . KLFK--KYHDVGKY-------------------------------IINTVTIILSLFKYL -SDKEKFEKYFRTFMCKRLINDKN----------------FNIVLDVKVFKTLK------ ----------KECGPQFTKKIETILK---DMKFSCKGMQDFYKETS-------------- -------------------------------HDGIKLLKKKKYAVNVIYN-------DVW EHNKLEG---EIIYPEAIRLCNDYFCKYYAL-------ANKAKNIKF-LPLYGLCTLKVD FGKVKGKKFPSSSGSSWERVDHREVGSRVG------------------------------ -----------KHTPCGERGTRGASRSGRSGPPEDKHNAHNDEYCQNERFLFTVTTLQAT VLLLFNERPQ-----------------------YSICELTSLTGFS-----REHLIEYLQ AIYTGDETN-ILIYDEAY------------------------------------------ --------------ENFQLNVNFQ----TENKYLVVNYSDQTY----------------- -------KDNTAIPA-LTQDDLELEDRSLHMDASIVKFLKTCGKASERDICAHTRQKV-- ----NNCTNEQIKSRLASLINREFIFL-QNN--IYYFEL >Plasmodium_berghei_XM_673692.1 . NDKI--DLHDVRKTRKENDDVDY--------TCDANIIETD---YLIKKMSDIVAIFNYI -SNKESFFEYYRIYLANRLINNMY----------------ISINVEKKFIESLY------ ----------FLCGSQYTSKLGGMIQ---NIINNKILNEKFYNYI--------------- -----------------NRNNSNGGISLPNLTNFDENYENNFFSVKILNK-------GYW PALEKTS----MKLSENFNKYILSYTEYYKT-------ENKNKKLEW-IYELSEVVFKYF INNR-------------------------------------------------------- ------------------------------------------------SYYLYCNLISAE IFLLFNKYKY-----------------------INYDIIKEELQID-----LKTFKDNMH SSLYYHK---IIYSNDDN------------------------------------------ ---------INWDTSNFYINENFS----YTNQNVYIK----------------------- --------KTTTLLS-KEHEKTKD-DKTMAIEAAIVRIMKTHKRLFYDQIFDHVKKVLS- ---TFAPSNQVIEKKIDLLVEREYIQK-EENSQVYVYIP >Cryptosporidium_muris_XM_002141506.1| . NWIA--NGLDKIIRNS------------------FINNNIL---EENKVLDTFLWLFKFI -PDKDMFEIIYRRLLCRRMLDFPD----------------AKRDLEHYVLVKFR------ ----------SECGFGYSVKMEGVLA---DLMQSELLNCQYKQFN--------------- ------------------------------SPNIISKIEPEQIKYNILTS-------GYW LIDKHVD----CCISEDIEIELSKFLYFFET-------KHERRKLQW-NFSIGKAQVTIN YQTE-------------------------------------------------------- --------------------------------------------DLVRSCILECTTLQMI VLYYLFNEFN----------------------SMTFGKIQDILKCS----DLSFLKMNLS SLCYDKENSPLRYIPNKNKNHNYTTSSSLDILRNSSKHDR-------------------- ----LTSKNISSLQEVWFIPDFEK-ISYDDYFEVNINQIYQKKTQDIIYLAP-------L EYISNKTDESKKTED-IFSKRINE-DRSHLIDSAIIKVLKKHKSLHTDDIVSKVMTMTE- ---VFQPTKGFILSRVTSLSERDFIATNPDSPYIYNYI- >Cryptosporidium_parvum_XM_626837.1 . NLIV--NGFDIVLRSL------------------YNDNKID---ENNKHLDTLFWLFKYV -SNKSLFEIKYRTLLCKRLMEFDV----------------NKRNIEHNIIIKLR------ ----------GECGHGYTLKLEGILA---DMIQSEILNMEFQQIN--------------- --------------------------------NEISVLSNTIINYKVITP-------NFW ITHPYIN----FSFLNNLNCKLDNFTQFFYS-------KYERRKLQW-HLGEGSAIINVN LKSR-------------------------------------------------------- ---------------------------------------------FNKSFTIECSTIQMF ILDIFNTFDF-----------------------ISFEEMQKIIGCSS---DINLLKHNLL CLVFENEP--LLNIIPITRWKEITINNKNLNENKGIIGVTELNICPKEHFPTN------- ---TNSLIASVSLTDIICINNDAN---VKDNSIIKYNYDSLDL----------------- -------NYEIKQNF-DSEGSSIR-DKGYIIDSIIVRNLKKNKTLHIDDITRRVINHNDV ---LLHGSTELIVERLEMLCQKEFVSKDLFSQNLYSYVP >Cryptosporidium_muris_XM_002140382.1| . ---------DRLNKKGG----------------IQNKYTQT---YIQELIRKLIELFSYI -HDQDYFLEIYKLQLAKRLLLNNV----------------QSEENELLFISLLK------ ----------NKCGPSFTIKLEGMLH---DMQLALDLNKRYKSYQ--------------- ----------------------DEMKVLNPQAMEHKIFPLMDFSVNVLTI-------STW PSLMVSD----LELPEEMQQYTRHFEEFYHK-------ETTHRKIVW-VHGYGQCIILGT WCPD-------------------------------------------------------- ----------------------------------------------DGNYEFHCNTFQAC ILLLFNHYKE-----------------------LSFSQIQSLLKVD-----ETILRKHIA SLTKPDIK--ILKQSFKDT----------------------------------------- --------SETETEYYFQIDNDFT----SQNRKIRLP----------------------- --------FPVQEEF-TFKTRIEE-DRSHTIEAAIVRIMKNKREISHSELVNEVTNQLK- ---SFKPNAKYLKNRIDYLIEREYIARHQENPLIYIYI- >Cryptosporidium_hominis_XM_663546.1 . KLVC--FYCDLLLKNSYSEIG----------NDFNVFQSNN---QFAVLAGKLVEIFSYI -HFQDYFLQIYKFLLAKRLLQYHL----------------SLEKNELYIISLLK------ ----------SKCGAGFTSKLEGMIM---DIRMTQNLNNKFKEYL--------------- -----KDIKKGEIENKEFEIKDNKISDLSLQIVKAPIPTKVDFAVNILTS-------SNW PTLDSSN----INLPTSLKNCISDFETFYFL-------ETSHRKLTW-IYWYGECVLDYK LPTP-------------------------------------------------------- -------------------------------------------NGTFKFFEIHCNTYQAC ILLQFNDFIS-----------------------LSLLELQSLLNTE-----KSIILKHIK PLYSDVG---ILKFVNNT------------------------------------------ --------QISTDNPVFEVNFEFA--STDVISPIIIK----------------------- -------LPHQTET--TQKNRTEY-DKSHAIEAAIVKIMKIKGQMTRSDIIAHVSSQLC- ---DYKPSERMIIDKIKYLIEREYLENNQDDPEKLLYLA >Cryptosporidium_parvum_XM_625899.1 . KLVC--FYCDLLLKNSYSEIG----------NDFNAFLSNN---QFAVLAGKLVEIFSYI -HFQDYFLQIYKFLLAKRLLQYHL----------------SLEKNELYIISLLK------ ----------SKCGAGFTSKLEGMIT---DIRMTRNLNNKFKEYL--------------- -----RDIKKGEIENKEFEIKDNKISDLGLQIVKALIPTKVDFAVNILTS-------SNW PTLDSSN----INLPTNLKNCISDFETFYSL-------ETSHRKLTW-IYWYGECVLDYK LPTP-------------------------------------------------------- -------------------------------------------NGTFKFFEIHCNTYQAC ILLQFNDFIS-----------------------LSLLELQSLLNTE-----KSIILKHIK PLYSDVG---ILKFVNNT------------------------------------------ --------QISPDNPVFEVNFEFV--STDVISPIIIK----------------------- -------LPHQTET--TRKNRTEY-DKSHAIEAAIVKIMKIKGQMTRSDIIAHVSSQLC- ---EYKPSEIMIIDKIKYLIEREYLENDQDDPEKLLYLA >Tetrahymena_thermophila_XM_001012772.2| . EQLN--CYIDEAFQKD------------------FKNKSE----QIEEVLNSVFEIFCLI -RNKDYFASIYMKSLAKRILYNKS-----------------LDENNEKIISKFK------ ----------LECGTVYTKKMETMFL---DMQQSLEYYNEFKLFI--------------- -----------------------------KNLNTKSAYKSLDFDIKVLTC-------GNW PYKLNFS----VKIPNQLEPYISEFEKHYKS-------KFKGRKLKW-IYSVGKSIVKGY YSFN-------------------------------------------------------- ------------------------------------------------NSKKEFVSNVMV ILLLFNNKIK-----------------------YT-QELTALL-MP-----YEEYKLHLL PLV-LK----ILKSE--------------------------------------------- ------------NNIDFEYNDQFS----YKNMRVQVN----------------------- ---VMKKEASKTES--SKNLEICL-ERKFVVESLIVKIMKSRRKMEHE--LYQEVARISH ---LFLP--DTVKQCVNSLINRDYIRL-SEN-KDYLYVV >Tetrahymena_thermophila_XM_001012757.2| . ELLA--NYTDFILKKE--------------------NLKQE---ELDSKLN-IIEIFNHL -TEKDIYLILYQK-LATRLLKAEL-------------KAGSRYDDESLMITKIK------ ----------GCCGG-ETKNYEGMIS---DIKYTMDLKKNFDEYM--------------- ----------------------------------NQKIKVVDLNVKVLE--------ANW PSYKSTT---EIILPPLYENLKEDFKKFYQL-------KKSQ-KLNW-INTLGSFDIKMN ITFD-------------------------------------------------------- ----------------------------------------------KSNFFLVNVSPLLC ILLQFEKVDTWIP--------------------IS-TILATIG-MKKDN--IAEFNKEVA LIG-KK----ILLASKSQT----------------------------------------- --------KEEKKDESDEVSFKFN----TFTYKKKFS----------------------- -------TVPEESQK-FKRDIVNE-NREHVIEATIVRIMKSRKTMKYGELVSEVNVLLR- ---KF--TQPHIKKRIESLVEREYIERDKNDMNLYHY-- >Tetrahymena_thermophila_XM_001014520.1| . -FLS--QYCDDLMKQ----------------------LTDH---ESNDRIE-VNAIFDYM NTSRDEFLLHYQQALCRRLIGFTS----------------KSMAAEKQIVTKFK------ ----------NSVGA-----LPTLNR----LNMLTDVETNEYNKE--------------- -------------------------------------KVNDILKIYVLNS-------VAW PLKRNEL---EKIIFPSSFAGIIDFTKYNQT-------YKQ-RKIFW-LFNEGSAEINFT SANKKTFA---------------------------------------------------- ------------------------------------------------GKYILRTTSYML ILMKMNEKAS-----------------------ITIQDLM-DTGIN-----KDSFDNNLK LIK-LK----ILSCAEED------------------------------------------ --------KYTESSTVQVNAFDFP-----KKVVPCLPR---------------------- ------APTSGPGAN-NPNIAIVE-ERTYIIKAYLVRIMKGRKVMAHNDLIKECVELIKT CARTFEPSFPHIRKCTESLIEEEYIKRENDY-NKYEYI- >Paramecium_tetraurelia_XM_001426177.1| . -YLA--IYADVSIRSE-------------------KGVNEI---ETDKKLNKIFSLF-LL -YSRDKFFQHQRL-LSSRLLNQTQ-----------------NINLEKNLLK-FK------ ----------GETT-NVLS--LKMVN---DISY-RFATDMIHKNQ--------------- ---------------------------------------KFDLTVYLLS--------GCW PINNIEI------IAPEMLSSLNLYEQIYLI-------KNNGRILLW-TYNLGGELNYKI ND---------------------------------------------------------- ------------------------------------------------KYYITATTFMIT FFL-FNKENE-----------------------LTIQQIERTIKII-------DLENSLI PFICLK----VLSRQKED------------------------------------------ ------LDEFSDKNEVIKLNLNY-----NNKKKLRVLPNPK------------------M QPKRQRKVGELTQEE-REYEELI--KRELVVDS-LVRTMKSKKSVTHSDLIAQCAQMIT- ---IFKPDIKFVKKRIENLIDREYIKRDERDCNLYHYL- >Paramecium_tetraurelia_XM_001435636.1| . -WLA--IYTDIIIRSE-------------------KGVNEM---ETDKRLSKIVSLFQLL -YQRDVFFRHYKF-LSNRLLNQL-------------------NILEKQLLK-FK------ ----------GETGTNVLTQLSSMIN---DIESNRFASDQISKDT--------------- ---------------------------------------KFDLNVFLLSQ-------GCW PITTILD----NVIKPIQINVLENYEKIYLG-------KHNGRILTW-CFNMGGELIYKL QAD--------------------------------------------------------- ------------------------------------------------KYYLNVNTMMIA FLL-FNAT-------------------------FSIKNILEMTKID-----KIDLENSLI PFVCLK----IIREKEIED----------------------------------------- ---------FSDENEILKLNLGFN----NRAKKMKLLPNPK------------------M QPKR-ISKVKEQNQE-ELQMEINK-QREFVVDS-LVRLMKSRKTIKHHELL-EN-CMIS- ---IFKPDILFIKKRIENLIEREYIRRDEKDWNIYHYL- >Tetrahymena_thermophila_XM_001012576.1| . --------------------------------------NEQ---EIEDRVE-IVGIFVYF -YSRDTFFKHYKF-FSNRLLNATS----------------RNKEAEKSLIARFK------ ----------TEAGT-GVNKIETMLK---DINNSEEFNDNRKHIS--------------- -------------------------------------PLGIELNVSVLTT-------GSW PIANTEK------VSTPVLKSSIEKFELYKS-------KYKGRNINW--LYSGTAEMFRS KE---------------------------------------------------------- ------------------------------------------------KYLLIVNSYMVA LLSISANTIS-----------------------YKL-VI---SGIP-----ENELEFLLM PFVKLK----ILNKSDEG------------------------------------------ --------DAFNNNSELSINSQF-----NKLKKIKCIPG--------------------- -GKAQQKKKEDDEGR-TFMEEMNR-EREFIVDACIVRIMKSRKTMKHNDLFPEVIKLIN- ---NFKPEIPLIKRRIESLLDRDYLKRDENDRNTFIYV- >Tetrahymena_thermophila_XM_001019597.2| . -FLA--KHCDELRVGM-------------------KGNSET---EIDEKLD-IIDIFLCF -DSRDSFITHYQKFLALRLLGNTL-----------------SDENEKKLITLIK------ ----------KEMGKSTTNKLTEMCT---DMVVNETMNDIKKKMK--------------- -------------------------------EIDSRKCDEIDWKITILTS-------GHW TIQKDIL-----DVPNELIWIADTYIKLYKE-------KHKGRKIDW-AFSQGNAEISTK FDK--------------------------------------------------------- ------------------------------------------------KYTLDVTNY-LL ILLMFNKADS-----------------------YTFKNISDVLKIP-----LPELHLNLI TLCKHK----LFNRDSKND----------------------------------------- -------LSEFKDDEVISVNTKFS----SKIVKIKMHPN-----------------PELK KALKNQEKTVNVNEN-EIEGELKK-LREH-LDACIVRIMKSRKTLALNDLNAEVVKLIGH ---IFKP---PIKQRIESLIERDYLIRHIDDRTKFIY-- >Ostreococcus_lucimarinus_XM_001416917.1| . EYLS--LYLDHMLRKS------------------SKDASQS---ELEIILNRSMGLFHLF -HEKDVFENYYRQHLSKRLLNKRS----------------ASDDNELAFIGKLK------ ----------DDCGFTFTSRMEGMFN---DMLTSGDLTREFEGVY--------------- ----------------------------------SRGSGSMEVNVSVLTT-------GAW PLKVHKT---PINLPHECERTCKVFENFYLS-------RHAGRKLTW-QANMGRADIKAR FASG-------------------------------------------------------- ------------------------------------------------EYEISASTLHMC VLMLFNTHET-----------------------LTTKDISDLTGMI-----GDELKGCLQ ALSCVKGKN-ILTKLPAG------------------------------------------ --------KDVSLGDSFQVNRDFS----SKTTKVKIL----------------------- --SISAKRENDHERS-LTKSKIVD-DRKPQIEATIVRVMKAKKRLDHNSIVMEVTAQVRN ---RFMPTPADIKKHIETLIEREYIERDPSDRKMYVYLA >Leishmania_major_XM_001683695.1| . EWLS--HYVNHLFQQE------------------AG--------PASAEMDRIVATLAYV -TERDRFIATSREHMADRILLPIK---------------KFSEANERALIQRFR------ ----------QRCGPTSTACLESMLH---DWETSNSFCAMEVLAS--------------- ----------------------------------KNVPRTFEVELLVAKK-------GIW PSRLSDE--PDIVVPSFLQRVLEPLRDDYLA-------GKSGRVLTW-SHECSSGELQGS FKKG-------------------------------------------------------- ------------------------------------------------TQLFFACGIQVL ILLCFNSSPV-----------------------CTPQQIGDRCHVT-----FASLQRYLP PLIRCR----ILTRKSGK------------------------------------------ --------ALLQMDDELTVNDDFV----CRARRMRIP----------------------- ---PSLARVSVGESE-HISKQVEE-DRKPAIDGALVRIMKGRRSLDHAELVLQCQQQLSS ---RFSPDVKLIKQRIEELIRREYISRDPRSKGVYHY-- >Leishmania_infantum_XM_001465991.1| . EWLS--HYVNHLFQHE------------------AG--------PASVEMDRIVATLAYV -TERDRFIATSREHMADRILLPVK---------------KFSEANERALIQRFR------ ----------QRCGPTSTACLESMLH---DWETSNSFRPMEVLAS--------------- ----------------------------------KNVPMTFEVELLVAKK-------GIW PSRLSDE--PDIVVPPFLQRVLEPLRDEYLS-------GKSGRVLTW-SHECSSGELQGS FKKG-------------------------------------------------------- ------------------------------------------------TQLFFACGIQVL ILLCFNSLPV-----------------------CTPQQIGDRCHAT-----FASLQRYLP PLIRSR----ILTRKSGK------------------------------------------ --------ALLQMDDELTVNDDFV----CRARRMRIP----------------------- ---PSLARVSVGESE-HISKQVEE-DRKPAIDGALVRIMKGRRSLDHAELVLECQQQLSS ---RFLPDVKLIKQRIEELIRREYISRDPRSKGVYHYIA >Leishmania_braziliensis_XM_001565450.1| . EWLS--HYVNHLFQQE------------------AG--------PASAEVDRIVATLAYV -TERDRFIATSREHMADRILFPVK---------------KFNEANERALIQRFR------ ----------QRCGPACTACLESMLH---DWEASNSFRAMEVLAS--------------- ----------------------------------KNIISPFEVNLLVAKK-------GIW PSRLSDE--PDIVVPSFLQRVLEPLRDEYLA-------GKSGRVLTW-SHECSSGELQGY FKKG-------------------------------------------------------- ------------------------------------------------TQLFYACGIQTL ILLCFNSSPV-----------------------CTPQQIGDRCHVT-----FASLQRYLS PLIRSR----VLTRKSGK------------------------------------------ --------ALLQLDDELTVNDEFV----CRARRMRLP----------------------- ---PSLARVSVVGSD-RISKQVEE-DRKPAIDGALVRIMKGRRSLEHAELILECQQHLSS ---RFSPDIKLIKQRIEELIRREYISRDSRNKGVYHYIA >Trypanosoma_cruzi_XM_802294.1| . ELLA--YYVDAVLQGN------------------EGS-------TVEENLEKAVAALAYV -TDRDTFLAHSRELLAQRILFPRK---------------KMDEATERSLIQRIS------ ----------QRCGVSSTSYLEGMLH---DVDIAEGFGVTEKLEA--------------- ----------------------------------VGKAPNFAFSVLVLKK-------GIW PPRIQGE---CFVPPRVIQEKLSAFQKIYLE-------GTTGRVLTW-SYSNSSGDVCAV FKKG-------------------------------------------------------- ------------------------------------------------VKILSMTGIQCW VVLAFNELNE-----------------------LTPNDMMSLFGMS-----LEDAKPALL PLLKCS----ILRGESDA------------------------------------------ --------TTIQPQAKFFINEDFS----SKWKKVRVP----------------------- --MPTCRRDGLLHGE-EIAKKIEE-DRRPAIDACLVRIMKSRRVLSHSSLVEECHQKLSQ ---LFSADQKLIKQRIEELIRKEYIERDHKNPSVYQYTA >Trypanosoma_brucei_AC159423.1| . ELLA--HYADSIIQGS------------------GCSS------SQEEELDRVITALSYV -TDRDTFLAHSRDLLAQRILSPKK---------------KFDDNIERSFAHRIS------ ----------HCCGVSSTCYLEGMLH---DVDVAEGFRAADKLEA--------------- ----------------------------------MGVKLPFAFDALVLKK-------GIW PPRIHSE---NFTPPPIISEALHSFEAAYLQ-------GTRGRVLTW-SYSNSSGDVHAA FKKG-------------------------------------------------------- ------------------------------------------------PKTLVMPGLQCW VLLAFNGANQ-----------------------LTVDDVVGRFGMT-----FDDAKPVLL SLVKAS----ILIRESNF------------------------------------------ --------PTVSLHDIFIVNDNFT----SKLKKMKIA----------------------- --MGRDQNIVAAQSE-EVAREVEE-DRKPAIDACLVRIMKSRRVLEHSMLVEECKERLLP ---TFSADPKLVKQRIEELIRKEFIERDANTPGLYRYAA >Phytophthora_sojae_AAQY01001184.1| . --MS--TFCDRILKTG------------------GEKLSDE---QVEDYLEKVVFVFSYL -TDKDLFAEIYRNQLAKRLLNQRS----------------ASADAEVLMIGKLK------ ----------LRCGAQFTGKMEGMMN---DLAIGSDHHQEFEGFL--------------- --------------------------KKQRESDSNEAALNLEFSVQVLTT-------GYW PSYRILE----VTMPPLMVRCMNLFKVYYDS-------KTSHRRLQW-VHSLGNATIRAN FPKKK------------------------------------------------------- ------------------------------------------------WYDLQVTTLQAV ALLLFNEGEGS----------------------LSFEAVRESLNLT-----VDVVKRIMH SLSCGKYK--LLTKTPAG------------------------------------------ --------KTISTSDGFTVNRTFA----SPMRKLRIP----------------------- --------MASLEES-HSQKNVEE-DRSIAIEAAIVRIMKARKTLQHQQLISEVLSQLAF ----FKPNLKVIKRRIEALIDREYLERDPDQANTYRYLA >Phytophthora_infestans_AATU01000547.1| . --MS--TFCDRILKTG------------------GEKLSDE---QVEDYLEKVVFVFSYL -TDKDLFAEIYRNQLAKRLLNQRS----------------ASADAEVLMIGKLK------ ----------LRCGAQFTGKMEGMMN---DLAIGSDHHQEFEGFL--------------- --------------------------KKQRESDSNEAALNLEFSVQVLTT-------GYW PSYRILE----VTMPPLMVRCMNLFKVYYDS-------KTSHRRLQW-VHSLGNATIRAN FPKKK------------------------------------------------------- ------------------------------------------------WYDLQVTTLQAV ALLLFNEGEGA----------------------LSFEAVHESLNVT-----VDVVKRIMH SLSCGKYK--LLAKTPAG------------------------------------------ --------KTISTSDQFAVNKTFA----SPMRKLRIP----------------------- --------MASLEES-HSQKNVEE-DRSIAIEAAIVRIMKARKTLQHQQLISEVLSQLAF ----FKPNLKVIKRRIEALIDREYLERDPDQANTYRYLA >Phytophthora_capsici_BT032185.1| . --MS--TFCDRILKTG------------------GEKLSDE---QVEDYLEKVVFVFSYL -TDKDLFAEIYRNQLAKRLLNQRS----------------ASADAEVLMIGKLK------ ----------LRCGAQFTGKMEGMMN---DLAIGSDHHQEFEGFL--------------- --------------------------KKQRESDSNEAALNLDFSVQVLTT-------GYW PSYRILE----VTMPPLMVRCMNLFKVYYDT-------KTSHRRLQW-VHSLGNATIRAN FPKKK------------------------------------------------------- ------------------------------------------------WYDLQVTTLQAV ALLLFNEGEGA----------------------LSFEAVRESLNLT-----VDVVKRIMH SLSCGKYK--LLTKTPAG------------------------------------------ --------KTISTSDQFAINKTFA----SPMRKLRIP----------------------- --------MASLEES-HSQKNVEE-DRSIAIEAAIVRIMKARKTLQHQQLISEVLSQLAF ----FKPNLKVIKRRIEALIDREYLERDPDQANTYRYLA >Hyaloperonospora_parasitica_ABWE01000108.1| . --MS--TFCDRILKTG------------------GEKLSDE---QVEDYLEKVVFVFSYL -TDKDLFAEIYRNQLAKRLLNQRS----------------ASDDAEVLMIGKLK------ ----------LRCGAQFTGKMEGMMN---DLAIGSDHHQEFDSFL--------------- --------------------------KKQRETSPSEAALNLEFSVQVLTT-------GYW PSYRILE----VTMPPLMVRCMNLFKVYYDS-------KTSHRRLQW-VHSLGNATIRAN FPTKK------------------------------------------------------- ------------------------------------------------WYDLQVTTLQAV AMLLFNEGNGA----------------------LSFEAVRESLNLS-----VDVVKRIMH SLSCGKYK--LLTKAPAG------------------------------------------ --------KTVSTSDEFSVNQTFA----SPMRKLRIP----------------------- --------MASLEES-HSQKNVEE-DRSIAIEAAIVRIMKARKTLQHQQLISEVLSQLAF ----FKPNLKVIKRRIEALIDREYLERDPDQANTYRYLA >Thalassiosira_pseudonana_AAFD02000002.1| . ELMS--TFCDRVLKSG------------------GEKLSET---EVEQSLDRIVQLFSFL -TDKDLFAEIYRNQLAKRLLNQRS----------------ASDDAEKLMIAKLK------ ----------VQCGTQFTSKMEGMLN---DLAVGSDQKSEFDARM--------------- ----------------------------------SQQGSSLSFGVQVLTT-------GFW PSYKAPE----VALPTQMTECMEVFKEWHDN-------KHQKRKLTW-VHSLGNATVRAT FGKK-------------------------------------------------------- ------------------------------------------------SYDLQVTTLQAV VLNAFNEGKT-----------------------LGLEDLKKTLNLD-----DQTLKPLMH SLSCGKHK--VLLKSPAS------------------------------------------ --------NKINSTDTFTSNAKFT----CNMRKIRIP----------------------- --------MASIEAS-HNKNRVEE-DRSIAIEAAIVRIMKARKTLKHQQLIAEVLSQLAF ----FKPQPRVIKKRIEALIDREYLERSSEDQQQYN--- >Oryza_sativa_japonica_AK110300.1| . ELLA--NYTDVLLNKT------------------GTRLDEK---KLESTLNNVVRIFSYL -TDKDLFSEFYRTLLSKRLLLGRS----------------ASTDAEKSLIGKLK------ ----------LKCGAQFTSKLEGMLN---DMRNASDHNQSFKDFL--------------- -----------------------------RDKKRDSELNGIDFSVQVLTT-------GFW PNGVSKT--EDVKLPAAMQSCMDVFRAFYDT-------HTNNRVLTW-LHNLGVVTLTGF FTKR-------------------------------------------------------- ------------------------------------------------KSDLVVSGVQAA ILLQFNEHND-----------------------LSIEELAKVTGLT-----PENLKAQLR VLVSGKYK--VLLKRPAE------------------------------------------ ---------GYKPDHRVSVNLAFS----DAQLRVRIP----------------------- PAMVVGGAVSEKERE-KDVESVEE-DRRHAVEACIVRIMKARKTLEHQQLMLEVSQQLMQ ---FFKPDPKAIKKRIEDLIAREYLERDAEKNTQYHYIA >Oryza_sativa_japonica_AK241711.1| . EFFI--IFLERLIEQR-----------------TCGKLDDD---SVEDTLAKVVKLLPYL -HSKDYLVELYRNRLLGRLSIGCN------------------IEVETSFITKLK------ ----------LVLDV---SILEDMLE---DYSISKELQKFFKDYM--------------- -------------------------------SMNPESNTLVDMDTMVLKQ-------GHF PSQQKQH----LSLPPDMLNCAEAFEKFYQEFHGQATGNRRGRTLTW-IYSLGNCNIVGN FEGK-------------------------------------------------------- ------------------------------------------------SVEMIVSPMQAA LLLLFNEDDR-----------------------LSYNDIVAKLEIM-----DNDAKVMLY SLSCGKYS--ILKKEPSN------------------------------------------ --------KTIAPDDIFEFNNNFS----VKTGKIKVP----------------------- ---LHHVDRGDFRAS-ETMEDVRR-YRKQNVDCAIVRIMKDRKTLDHEKLVEECKKLCDP ---YFKVDDDLIQMRIDHLVAENYLAR------------ >Ostreococcus_tauri_CR954207.4| . QLLA--DFSDKLLRKG-----------------GSEKLSDE---KMEETLEKVVKLLAFI -SDKDMFGEFYRKKLARRLLTDSS----------------ASQDYERSILSKLK------ ----------TQCGAQFTGKMEGMLN---DLQSARETQDTFERWM--------------- ------------------------------EEDAANRKPPLDFSVTILTH-------GFW PQHKPVE----FQLNDELAKCVDTFRSFYDK-------RMGQRKLTW-IHHLGTATVVGK FETK-------------------------------------------------------- ------------------------------------------------SIEMLMQTTQCA VLLLFGAKTE-----------------------LTMQNVIDLTKLP-----PDDAKRALY SLSCAKYK--ILNKSPEG------------------------------------------ --------KTIGPDDVFAFNEKFT----DRSRRIKIG----------------------- -------LPPVDEKK-VTIEHVEH-DRRHAIDAAIVRTMKARKSLAYNQLIIEVVSQLKQ ---KFVPEPKQIKIRVEELINKEFIERDKENPQVFKYMA >Ostreococcus_lucimarinus_XM_001418551.1| . QLLA--DFADKLLRKG-----------------GSEKLSDE---KMEETLDKVVKLLAYI -SDKDMFGEFASKRLSRRLLQDTS----------------ASQDYERSILSKLK------ ----------TSCGAQFTSKMEGMVN---DVQSARDTQDVFERWV--------------- ------------------------------DEDAANRKTCIDFNVTILTH-------GFW PSWKPIQ----VELCDEFAQCVETFQTFYDA-------KMSQRKLTW-VHQLGAVVLNVK YEAK-------------------------------------------------------- ------------------------------------------------TIEMHMQTPQCS VLLLFRNEKE-----------------------LSMQKVIEKTKMP-----ADAVKRALY SLSCAKYK--ILNKSPEG------------------------------------------ --------KTVNPEDVFSFNEKFT----DRSRRIKIA----------------------- -------LPPPDERK-ATIENVVQ-DRRHAIDAAIVRVMKTRKALAYNELVVEVVNQLQQ ---SFLPEAKMIKMRVDDLINKEYIMRDEENSQVFKYIA >Chlamydomonas_reinhardtii_XM_001692883.1_cul3| . ELMA--SFCDNLLKKG-----------------GSEKLSDE---AIEETLEKVVKLLAYV -SDKDMFAEFYRKKLSRRLLQDKS----------------ASDDHERSLLSRLK------ ----------QQCGAQFTSKMEGMVT---DLQLAKEKQQHFDDWL--------------- ---------------------------------KKGSKLPIDLSVTVLTT-------GFW PTYKSID----VALPREMVEGVEVYRSYYDS-------DSKHRKLTW-IYTLGTAVLRGN FDSK-------------------------------------------------------- ------------------------------------------------PIEMQMNTLQAA LCMLLNDVDE-----------------------LSYGEIQERLRLP-----DDDLQRLLH SLVCAKYK--IIKKDPDG------------------------------------------ --------KSIGKSDKFAFNNRFT----DKMRRIKIP----------------------- -------LPPLDEKK-KVMEDVDK-DRRYAIDAAIVRIMKSRKVLQHQTLVMEVIQQLQR ---MFKPDLKLIKKRIEDLIQREYLERDKDNPTLFKYLA >Arabidopsis_thaliana_NM_100179.3 . EILA--TYCDNILKTGG----------------GIEKLENE---DLELTLEKVVKLLVYI -SDKDLFAEFFRKKQARRLLFDRN----------------GNDYHERSLLTKFK------ ----------ELLGAQFTSKMEGMLT---DMTLAKEHQTNFVEFL--------------- -------------------------------SVNKTKKLGMDFTVTVLTT-------GFW PSYKTTD----LNLPIEMVNCVEAFKAYYGT-------KTNSRRLSW-IYSLGTCQLAGK FDKK-------------------------------------------------------- ------------------------------------------------TIEIVVTTYQAA VLLLFNNTER-----------------------LSYTEILEQLNLG-----HEDLARLLH SLSCLKYK--ILIKEPMS------------------------------------------ --------RNISNTDTFEFNSKFT----DKMRRIRVP----------------------- -------LPPMDERK-KIVEDVDK-DRRYAIDAALVRIMKSRKVLGHQQLVSECVEHLSK ---MFKPDIKMIKKRIEDLISRDYLERDTDNPNTFKYLA >Arabidopsis_thaliana_NC_003070.6 . EILA--TYCDNILKTRG----------------GSEKLSDE---ATEITLEKVVNLLVYI -SDKDLFAEFYRKKQARRLLFDRS----------------GIMKEERSILTKLK------ ----------ELLGGQLTSKMEGMVT---DITLARELQTNFVDYL--------------- -------------------------------SANMTTKLGIDFTVTVLTT-------GFW PSYKTTD----LNLPTEMVNCVEAFKVFYGT-------KTNSRRLSW-IYSLGTCHILGK FEKK-------------------------------------------------------- ------------------------------------------------TMELVVSTYQAA VLLLFNNAER-----------------------LSYTEISEQLNLS-----HEDLVRLLH SLSCLKYK--ILIKEPMS------------------------------------------ --------RTISKTDTFEFNSKFT----DKMRKIRVP----------------------- -------LPPMDERK-KVVEDVDK-DRRYAIDAALVRIMKSRKVLAHQQLVSECVEHLSK ---MFKPDIKMIKKRIEDLINRDYLERDTENANTFKYVA >Oryza_sativa_Japonica_AK073477.1 . ELFA--AYCDSILKRG-----------------GSEKLSDE---AIDESLEKVVKLLTYL -SDKDLFVEFHRKKLGRRLLFDKN----------------TNDEHERILLSKLK------ ----------QFFGGQFTSKMEGMLK---DITLAKEHQSSFEEYV--------------- -------------------------------SNNPESNPLIDLNVTVLTT-------GYW PTYKNSD----INLPLEMVKCVEVFKEYYRS-------DKQHRKLTW-IFSLGNCVVIGN FDAK-------------------------------------------------------- ------------------------------------------------PVEFVLNTYQAA LLLLFNEADK-----------------------LSYSDIVSQLKLS-----DDDAVRLLH SLSCAKYK--ILNKEPSN------------------------------------------ --------RVISPEDEFEFNSKFT----DRMRRIKVP----------------------- -------LPQIDEKK-KVVDDVNK-DRRFAIDASLVRIMKSRKVLGHQQLVAECVEQLSR ---MFKPDIKIIKRRIEDLISREYLERDSENAQTYKYLA >Nicotiana_tabacum_AJ344533.1 . ELLA--SYCDNILKKG-----------------GSEKLSDD---AIEETLDKVVKLLAYI -SDKDLFAEFYRKKLSRRLLFDKS----------------ANDDHERLILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTLAKENQNHFQEYL--------------- -------------------------------SNNSAANPGIDLTVTVLTT-------GFW PSYKSSD----LSLPVEMVKCVEVFKEFYQT-------KTKHRKLTW-IYSLGTCNINGK FEPK-------------------------------------------------------- ------------------------------------------------TIELIVGTYQAA ALLLFNASDR-----------------------LSYSHIKSQLNLA-----DDDLVRLLQ SLSCAKYK--ILTKEPTS------------------------------------------ --------RTVSSTDHFEFNSKFT----DRMRRIRIP----------------------- -------LPPVDERK-KVVEDVDK-DRRYAIDACIVRIMKSRKVLPHSQLVSECVEQLSR ---MFKPDFKAIKKRIEDLITRDYLERDKENPNLFKYLA >Nicotiana_tabacum_AJ344534.1 . ELLA--SYCDNILKKG-----------------GSEKLSDD---AIEETLDKVVKLLAYI -SDKDLYAEFYRKKLSRRLLFDKS----------------ANDDHERLILTKLK------ ----------QQCGGQFTSXMEGMVT---DLTLARENQNHFQEYL--------------- -------------------------------SNNPAASPGIDLTVTVLTT-------GFW PSYKSSD----LSLPVEMVKSVEVFKEFYQT-------KTKHRKLTW-IYSLGTCNINGK FAPK-------------------------------------------------------- ------------------------------------------------TIELIVGTYQAA ALLLFNASDR-----------------------LSYSEIKSQLNLA-----DDDLVRLLH SLSCAKYK--ILTKEPSN------------------------------------------ --------RTVSPSDHFEFNSKFT----DRMRRIRVP----------------------- -------LPPADERK-KVVEDVDK-DRRYAIDACIVRIMKSRKVLPHQQLVLECVEQLSR ---MFKPDFKAIKKRIEDLITRDYLERDKENPNLFKYLA >Petunia_integrifolia_DQ250017.1| . ELLA--SYCDNILKKG-----------------GSEKLSDD---AIEETLDKVVKLLAYI -SDKDLFAEFYRKKLSRRLLFDKS----------------GNDDHERLILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTLAKENQNHFQEYL--------------- -------------------------------SNNPAASPGIDLTVTVLTT-------GFW PSYKSSD----LRLPMEMVKCVEVFKEFYQT-------KTKHRKLTW-IYSLGTCHINGK FEPK-------------------------------------------------------- ------------------------------------------------TIELVLGTYQAA VLLLFNASDR-----------------------LSYSDIKSQLNLA-----DDDLVRLLQ SLSCAKYK--ILTKDPSN------------------------------------------ --------RTVSSTDHFEFNSKFT----DKMRRIRVP----------------------- -------LPPVDERK-KVVEDVDK-DRRYAMDACIVRIMKSRKVLPHQQLVLECVEQLSR ---LFKPDFKEIKKRIEDLITREYLERDQENPNVFKYLA >Solanum_lycopersicum_EF647606.2| . ELLA--SYCDSILKKG-----------------GSEKLSDD---AIEETLDKVVKLLAYI -NDKDLFGEFCRKKLSRRLLFSKC----------------ANDEHERLMLTKLK------ ----------QYCGGQFTSKMEGMVT---DLTLAKENQNDFQEYL--------------- -------------------------------SNN--ASTGIDLTVTVLTS-------GFW PSYKSCD----LSLPVEMAKCVQVFNEFYQT-------TTKHRKLTW-IYSLGTCNVIGK FDSK-------------------------------------------------------- ------------------------------------------------TIELILGTYQAA VLSLFNSSDR-----------------------LSYSEIKSQLNLA-----DDDLIRLLQ SLSCAKYK--ILIKDPSN------------------------------------------ --------ATVTSSDHFEFNSKFT----DRMRRVRVP----------------------- -------LPLVDERK-KVVEDVGK-DRRYAIDACIVRIMKSRKVLPHQQLVAECVEQLSS ---MFKPDLKAIKKQIEDLITREYLERDEENPNLFKYLA >Oryza_sativa_Japonica_AC105772.5| . ELLA--TFCDNILKKG-----------------CSEKLSDE---AIEDALEKVVRLLAYI -SDKDLFAEFYRKKLARRLLFDKS----------------ANDEHERSILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTVARDHQTKFEEFV--------------- -------------------------------AAHQELNPGIDLAVTVLTT-------GFW PSYKTFD----INLPAEMVKCVEVFKEFYQT-------RTKHRKLTW-IYSLGTCNINAK FEAK-------------------------------------------------------- ------------------------------------------------TIELIVTTYQAA LLLLFNGSDR-----------------------LTYSEIVTQLNLS-----DDDVVRLLH SLSCAKYK--ILNKEPAN------------------------------------------ --------RSISPNDVFEFNSKFT----DRMRRIKIP----------------------- -------LPPVDEKK-KVVEDVDK-DRRYAIDASIVRIMKSRKVMGHQQLVAECVEQLSR ---MFKPDFKAIKKRIEDLITRDYLEREKDNANVYRYLA >Zea_mays_AY106256.2 . ELLA--TFCDNILKKG-----------------CSEKLSDE---AIEDALEKVVRMLAYI -SDKDLFAEFYRKKLARRLLFDKS----------------ANDEHERSILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTVARDHQTKFEEFV--------------- -------------------------------AGHPELNPGIDLAVTVLTT-------GFW PSYKTFD----INLPAEMVKCVEVFKEFYQT-------RTKHRKLTW-IYSLGTCNINAK FDAK-------------------------------------------------------- ------------------------------------------------PIELIVTTYQAA LLLLFNGSER-----------------------LSYSEIATQLNLS-----DDDVVRLLH SLSCAKYK--ILNKEPAS------------------------------------------ --------RSISPNDVFEFNSKFT----DRMRRIKIP----------------------- -------LPPVDEKK-KVVEDVDK-DRRYAIDASIVRIMKSRKVMGHQQLVAECVEQLSR ---MFKPDFKAIKKRIEDLITRDYLERDKDNANTYKYLA >Oryza_sativa_japonica_AP003236.3 . ELLA--TFCDNILKKG-----------------GSEKLSDE---AIEDTLEKVVRLLAYI -SDKDLFAEFYRKKLARRLLFDKS----------------ANDEHERSILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTVARDHQAKFEEFI--------------- -------------------------------STHSELNPGIALAVTVLTT-------GFW PSYKSFD----INLPAEMVKCVEVFKEFYQT-------RTKHRKLTW-IYSLGTCNINAK FEAK-------------------------------------------------------- ------------------------------------------------TIELIVTTYQAA LLLLFNGVDR-----------------------LSYSEIVTQLNLS-----DDDVVRLLH SLSCAKYK--ILSKEPNN------------------------------------------ --------RSISPNDVFEFNSKFT----DKLRRLKIP----------------------- -------LPPVDEKK-KVVEDVDK-DRRYAIDASIVRIMKSRKVLGHQQLVMECVEQLGR ---MFKPDFKAIKKRIEDLITRDYLERDKDNPNVYRYLA >Physcomitrella_patens_XM_001774409.1| . ELLA--TFCDNLLKKG-----------------GSEKLSDE---AIEDTLEKVVKLLAYI -SDKDLFAEFYRKKLARRLLFDKS----------------ANDDHERSILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTLARENQINFEEYL--------------- -------------------------------SDNTQSNPGIDLTVTVLTT-------GFW PSYKSSD----LALPAEMVKCVEVFKEFYQT-------KTKHRKLTW-IYSLGTCNITGK FDAK-------------------------------------------------------- ------------------------------------------------PIELIVTTYQAA VLLLFNAADR-----------------------LSYNDIKSQLNLT-----DEDIVRLLH SLSCAKYK--ILNKDPIT------------------------------------------ --------KTVGQSDIFEFNTKFT----DKMRRIKIP----------------------- -------LPPMDEKK-KVIEDVDK-DRRYAIDASIVRIMKSRKMLPHQQLVLECVEQLGR ---MFKPDFKVIKKRVEDLIAREYLERDKDNPNVFKYVA >Physcomitrella_patens_XM_001773861.1| . ELLA--TFCDNLLKKG-----------------GSEKLSDE---AIEDTLEKVVKLLAYI -SDKDLFAEFYRKKLARRLLFDKS----------------ANDDHERSILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTLARENQSNFEDYL--------------- -------------------------------SDNTKSNPGIDLTVTVLTT-------GFW PSYKSSD----LALPAEMVKCVEVFKEFYQT-------KTKHRKLTW-IYSLGTCNITGK FDAK-------------------------------------------------------- ------------------------------------------------PIELIVTTYQAA VLLLFNAEDR-----------------------LSYNDIKNQLNLT-----DEDIVRLLH SLSCAKYK--ILNKDPNT------------------------------------------ --------KAVGQNDIFEFNTKFT----DKMRRIKIP----------------------- -------LPPMDEKK-KVIEDVDK-DRRYAIDASIVRIMKSRKMLPHQQLVLECVEQLGR ---MFKPDFKVIKKRVEDLIARDYLERDKDNPNMFKYVA >Thalassiosira_pseudonana_AAFD02000009.1| . ----------------------------------------------EAFQNEVMALFRHV -NSKDVFEAFYKRNLAKRLLTGRS----------------VSSDMERSFLSKLK------ ----------AECGAGYTSKMEGMFK---DMELSRDIMSSYSAYS--------------- -------------------SGATSAQAQPMPVPHLGSGKATEMDVQVLTT-------GYW PVYPKYP---GILLPPEIVAHQAKFESYYKN-------KYQGRRIAW-QYSLGNCIVKAN FPKQ-------------------------------------------------------- ----------------------------------------------PAGKELLVNLCQTL VLLCFQYEDGPDGK------------------GLTIGDIVKKTGID-----RDEVERVLQ SLSLGRDGTRVLIKVDHDSPDAIPPASTSGDDSPTKKKK--------------------- ------IRRNVGPHDRFLFNASFV----SNQRRIRIT----------------------- ---NITMKETSEERK-ETHEAVSK-DRLYIIDATVVRIMKARKTIDHRLLMGEVMTQL-- ---KFPASAADVKKRVESLIEREYMERVEGDRSRYNYLA >Phaeodactylum_tricornutum_XM_002178572.1| . ELLA--KFLDQILRSN------------------KKMDQYQ-SESEQWLQRIISGLFIPL -QAKDIFEAFYKRDLAKRLLWNRV----------------VNMDVEKQVCSLLK------ ----------AECGAGFTSKMEGMFQ---DVDWSRETMMVYKQST--------------- -------------------------------ADILPTENSVEMEAQVLTTGFLPRIPGYW PVYPQYP---NLHLPESLKEPQERFGNHYKI-------KYQGRRMTW-QYALGHCVVRSS GFPK-------------------------------------------------------- ------------------------------------------------TYEFVVSLCQAL VLIQFEEADT----------------------KLSLPTLMQAIGLE----DRDEMERVLQ SLALGKDGTRILRKLDYDSEPNKKKK---------------------------------- ------IRMNVDNRDEFTINRKFE----SNQRRIRIN----------------------- ---NIMMKESKEERE-KTVEAVSR-DRLYLIDAVLVRIMKARKTILHQTLIPQVVEQV-- ---KVPAQPGDIKQRIESLIEREYMERDAKDRNRYNYLA >Physcomitrella_patens_XM_001771910.1| . ELLA--TFCDNLLKKGG-----------------SEKLSDE---AIEDTLEKVVKLLAYI -SDKDLFAEFYRKKLARRLLFDKS----------------ANDDHERSILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTLARENQTNFEEYL--------------- -------------------------------TENIQSSPGIDLTVTVLTT-------GFW PSYKSSD----LALPAEMVKCVEVFKEFYQT-------KTKHRKLTW-IYSLGTCNITGK FDAK-------------------------------------------------------- ------------------------------------------------PIELIVTTYQAA VLLLFNAEDR-----------------------LSYNDIKNQLNLT-----DEDIVRLLH SLSCAKYK--ILNKDPHT------------------------------------------ --------KTVGQTDTFEFNTKFT----DKMRRIKIP----------------------- -------LPPMDEKK-KVIEDVDK-DRRYAIDASIVRIMKSRKVLPHQQLVLECVEQLGR ---MFKPDFKVIKKRVEDLIAREYLERDKDNPNMFKYVA >Picea_sitchensis_EF678052.1| . ELLA--TFCDNILKKG-----------------GSEKLSDE---DIEDTLEKVVKLLAYI -SDKDLFAEFYRKKLARRLLFDKS----------------ANDDHERSILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTLARENQTNFEEYL--------------- -------------------------------NENPLAHPGIDLTVTVLTT-------GFW PSYKSFD----LNLPAEMVKCVEVFKEFYQT-------KTKHRKLTW-IYSLGTCNIIGK FDPK-------------------------------------------------------- ------------------------------------------------PMELIVTTYQAS ALLLFNASER-----------------------LSYSEIKSQLNLT-----DEDIVRLLH SLACAKYK--ILNKEPNT------------------------------------------ --------KTVAQTDYFEFNAKFT----DKMRRIKIP----------------------- -------LPPVDEKK-KVIEDVDK-DRRYAIDASIVRIMKSRKVLSHQQLVMECVEQLGR ---MFKPDFKAIKKRMEDLITREYLERDKDNPNMFRYLA >Medicago_truncatula_AC146552.16 . ELLA--TFCDNILKKG-----------------GSEKLSDE---AIEETLEKVVKLLAYI -SDKDLFAEFYRKKLARRLLFDKS----------------ANDDHERSILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTLAKENQTSFEEYL--------------- -------------------------------SNTPNADPGIDLTVTVLTT-------GFW PSYKSFD----LNLPAEMVKCVEVFKEFYST-------KTKHRKLTW-IYSLGTCNISGK FDPK-------------------------------------------------------- ------------------------------------------------TVELVVTTYQAS ALLLFNSSDR-----------------------LSYSEIMTQLNLL-----DEDVIRLLH SLSCAKYK--ILIKEPNT------------------------------------------ --------KTILPTDYFEFNAKFT----DKMRRIKIP----------------------- -------LPPVDEKK-KVIEDVDK-DRRYAIDASIVRIMKSRKVLGYQQLVMECVEQLGR ---MFKPDVKAIKKRIEDLISRDYLERDKENPNMFKYLA >Olea_europaea_AY059387.2 . ELIA--KFVDEKLRAG------------------NKGTSEE---ELEGILDKVLVLFRFI -QGKDVFEAFYKKDLAKRLLLGKS----------------ASIDAEKSMITKLK------ ----------TECGSQFTSKLEGMFK---DIELSKEINESFKQSS--------------- -------------------------------QARTKLPSGIEMSVHVLTT-------GYW PTSPPMD----VRLPHELNVYQDIFKEFYLS-------KHSGRRLMW-HNSLGHCVLESQ NFQK-------------------------------------------------------- ----------------------------------------------VERSWLFLYFRRLC CAHLTMHKT------------------------LASQDIKESTGI------LRIKSEEDS AIPCMRKSP-RSSENSQG------------------------------------------ --------ERCGGLCSFVFNDQFT----APLYRIKVN----------------------- ---AIQMKETVEENA-STTERVFQ-DRQYQVDAAIVRIMKTRKVLSHTLLITELFQQL-- ---KVPHKTSDLKKRIESLIDREYLERDKNNPQVYNYLA >Lycopersicon_esculentum_Y16124.1 . ELIA--KFLDEKLRAG------------------NKGTSEE---ELEGTLDKVLVLFRFI -QGKDVFEAFYKKDLAKRLLLGKS----------------ASIDAEKSMISKLK------ ----------TECGSQFTNKLEGMFK---DIELSKEINESFKQSS--------------- -------------------------------QARTKLPTGIEMSVHVLTM-------GYW PTYPPMD----VRLPHELNVYQDIFKEFYLS-------EYSGRRLMW-QNSLGHCVLESW NIQK-------------------------------------------------------- ----------------------------------------------EKRSSQFLFSRLLF CALLMMRKI------------------------LASQDIKEATGI------LRIKSEKDS TVSCMWKSS-CSPEDSKR------------------------------------------ --------KRCGGLCTFVFLYQFT----APLYRIKVN----------------------- ---AIQMKETVEENT-STTERVFQ-DRQYQVDAAIVRIMKTRKVLSHTLLITELFQQL-- ---KFPNKTSYLKKRIESLIDREYLERDKNNPQIYNYLA >Solanum_lycopersicum_EU218537.1| . ELIA--KFLDEKLRAG------------------NKGTSEE---ELEGTLDKVLVLFRFI -QGKDVFEAFYKKDLAKRLLLGKS----------------ASIDAEKSMISKLK------ ----------TECGSQFTNKLEGMFK---DIELSKEINESFKQSS--------------- -------------------------------QARTKLPTGIEMSVHVLTM-------GYW PTYPPMD----VRLPHELNVYQDIFKEFYLS-------KYSGRRLMW-QNSLGHCVLKAE YPKG-------------------------------------------------------- ------------------------------------------------KKELAVSLFQTV VLMLFNDAEN-----------------------LSFQDIKEATGIE-----DKELRRTLQ SLACGKVR--VLQKIPKG------------------------------------------ --------RDVEDDDTFVFNDQFT----APLYRIKVN----------------------- ---AIQMKETVEENT-STTERVFQ-DRQYQVDAAIVRIMKTRKVLSHTLLITELFQQL-- ---KFPIKPADLKKRIESLIDREYLERDKNNPQIYNYLA >Arabidopsis_thaliana_AY091113.1_At5g46210 . ELIA--KFLDEKLRAG------------------NKGTSEE---ELESVLEKVLVLFRFI -QGKDVFEAFYKKDLAKRLLLGKS----------------ASIDAEKSMISKLK------ ----------TECGSQFTNKLEGMFK---DIELSKEINESFKQSS--------------- -------------------------------QARTKLPSGIEMSVHVLTT-------GYW PTYPPMD----VKLPHELNVYQDIFKEFYLS-------KYSGRRLMW-QNSLGHCVLKAD FSKG-------------------------------------------------------- ------------------------------------------------KKELAVSLFQAV VLMLFNDAMK-----------------------LSFEDIKDSTSIE-----DKELRRTLQ SLACGKVR--VLQKNPKG------------------------------------------ --------RDVEDGDEFEFNDEFA----APLYRIKVN----------------------- ---AIQMKETVEENT-STTERVFQ-DRQYQIDAAIVRIMKTRKVLSHTLLITELFQQL-- ---KFPIKPADLKKRIESLIDREYLEREKSNPQIYNYLA >Oryza_sativa_japonica_NT_107187.1 . ELIA--KFLDEKLRAG------------------NKGTSEE---ELEGILDKVLVLFRFI -QGKDVFEAFYKKDLAKRLLLGKS----------------ASIDAEKSMITKLK------ ----------TECGSQFTNKLEGMFK---DIELSKEINESFKQSS--------------- -------------------------------QARTKLPSGIEMSVHVLTT-------GYW PTYPPMD----VKLPHELNVYQDIFKEFYLS-------KYSGRRLMW-QNSLGHCVLKAE FPKG-------------------------------------------------------- ------------------------------------------------KKELAVSLFQSV VLMLFNDAQK-----------------------LSFLDIKESTGIE-----DKELRRTLQ SLACGKVR--VLQKMPKG------------------------------------------ --------RDVEDKDEFVFNEEFS----APLYRIKVN----------------------- ---AIQMKETVEENT-STTERVFQ-DRQYQVDAAIVRIMKTRKTLSHTLLITELFQQL-- ---KFPIKPSDIKKRIESLIDREYLERDRSNPQIYNYLA >Zea_mays_BT018674.1 . ELIA--KFLDEKLRAG------------------NKGTSEE---ELEGILDKVLVMFRFI -QGKDVFEAFYKKDLAKRLLLGKS----------------ASIDAEKSMITKLK------ ----------TECGSQFTNKLEGMFK---DIELSKEINDSFRQSS--------------- -------------------------------QARTKLPSRIEMSVHVLTT-------GYW PTYPPMD----VKLPHELNVYQDIFKEFYLS-------KYSGRRLMW-QNSLGHCVLKAD FPKG-------------------------------------------------------- ------------------------------------------------KKELAVSLFQSV VLMLFNDAQK-----------------------LSFLDIKDSTGIE-----DKELRRTLQ SLACGKVR--VLQKIPKG------------------------------------------ --------RDVEDKDDFVFNEDFS----APLYRIKVN----------------------- ---AIQMKETVEENT-STTERVFQ-DRQYQVDAAIVRIMKTRKVLSHTLLITELYQQL-- ---KFPVKPADIKKRIESLIDREYLERDRSNPQIYNYLA >Physcomitrella_patens_XM_001764728.1| . ELIA--KFIDGKLRSG------------------NKGTSEE---ELEGILDKVLVLFRFI -QGKDVFEAFYKKDLAKRLLLGKS----------------ASIDAEKSMISKLK------ ----------TECGSQFTNKLEGMFK---DIELSREINESFRQSA--------------- -------------------------------QARLKLPSGIEMNVHVLTT-------GYW PTYPPME----VRLPRELNVYQDIFKEFYLS-------KHSGRRLMW-QNSLGHCVLKAN FPKG-------------------------------------------------------- ------------------------------------------------KKELSVSLFQTL VLMLFNDAQS-----------------------LTFHDIKDTSAIE-----DKELRRTLQ SLACGKIR--VLNKIPKG------------------------------------------ --------REVEDEDTFVFNEDFV----APLFRIKVN----------------------- ---AIQLKETVEENT-TTTERVFQ-DRQYQIDAAIVRIMKTRKVLSHTLLITELFQQL-- ---KFPIKPADLKKRIESLIDREYLERDKANPQIYNYLA >Physcomitrella_patens_XM_001776282.1| . ELIA--KFIDGKLRAG------------------NKGTSEE---ELEGILDKVLVLFRFI -QGKDVFEAFYKKDLAKRLLLGKS----------------ASIDAEKSMISKLK------ ----------TECGSQFTNKLEGMFK---DIELSREINESFRQSA--------------- -------------------------------QARMKLPSGIEMNVHVLTT-------GYW PTYPPME----VRLPHELNVYQDIFKEFYLS-------KHSGRRLMW-QNSLGHCVLKAN FPKG-------------------------------------------------------- ------------------------------------------------KKELSVSLFQTV VLMLFNDAQS-----------------------QSFQEIKDTTAIE-----DKELRRTLQ SLACGKVR--VLNKQPKG------------------------------------------ --------REVEDDDIFVFNEDFV----APLFRIKVN----------------------- ---AIQLKETVEENT-STTERVFQ-DRQYQIDAAIVRIMKTRKVLSHTLLITELFQQL-- ---KFPIKPADLKKRIESLIDREYLERDKANPQIYNYLA >Ostreococcus_lucimarinus_XM_001417094.1| . ELIA--KYIDSKLKSG------------------NKGASEE---ELETTLDKALTLFRYI -VGKDVFEGFYKKELAKRLLHAKS----------------ASIDAEKSMISKLK------ ----------AECGSQFTQHLEGMFK---DIDLSREIMQSFRQTF--------------- --------------------------------DDEALTKGIEMNVNVITQ-------GCW PSYPVID----VNIPEQLAVLQEKFQDFYLG-------KHSGRQLTW-QNSQGHCVLKAR FGSG-------------------------------------------------------- ------------------------------------------------MKELSVSLFQCV VLMLFNDAEK-----------------------LSYEDIASKSGLE-----EKELKRALQ SLACAKVR--ILNKEPKS------------------------------------------ --------RDVNAGDVFEVNAALN----ERLFRIKVN----------------------- ---SIQIKETTEENK-QTMERVFQ-DRQQQVDAAIVRVMKTRKSLTHALLISELMAQL-- ---KFPTKASDLKKRIESLIEREYIERDREDAQKYNYLA >Ostreococcus_tauri_CR954204.4| . ELIA--KYIDSKLKSG------------------SKGLSEE---ELERTLDKALTLFRYI -VGKDVFEVFYKKELSKRLLHGKS----------------ASIDAERSMIQKLK------ ----------AECGSQFTQHLEGMFK---DIDLSREIMQSFRQTF--------------- -----------------------------------ENDPIIEMNVNVITA-------GCW PSYPSVD----VKLPEELANLQEKFMSFYLG-------KHSGRKLTW-QNSEGHCVLKAR FDGG-------------------------------------------------------- ------------------------------------------------MKELSVSLFQCV ILMLFNDSKK-----------------------LSYTEIAQKTGME-----EKELKRALQ SLACAKVR--ILNKEPKS------------------------------------------ --------REINDDDSFEVNTALN----ERLFRIKVN----------------------- ---SIQVKETAEENK-QTMERVFQ-DRQQQIDAAIVRVMKTRKSLTHALLISELMAQL-- ---KFPTKASDLKKRIESLIEREYLERDREDAQTYNYLA >Chlamydomonas_reinhardtii_XM_001703167.1| . --------------------------------------SEE---ELEAALDRALILFRYI -QGKDVFEAFYKKDLAKRLLLGRS----------------ASVDAEKAMIAKLKARRRSG GRARARARGRLLQPSQFTAKLEGMFK---DVELSDDVMAAFRGAP--------------- --------------------------------AAAGLPSGVDVAVSVLTS-------GYW PTYPVTE----VKLPEVLDRAGAVFRDFYLS-------KYSGRRLVW-QHSLGSCMLRAS FPKG-------------------------------------------------------- ------------------------------------------------MKELSVSTFQAA VLMLFNDTDT-----------------------LSYKDVLAGTGLE-----EKELKRTLQ SLACGKVR--VLTKEPKG------------------------------------------ --------RDVNDDDSFSFNTGFT----EKLFRIKIN----------------------- ---SIQMKETEEENK-KTNEQVLQ-DRQYQIDAALVRIMKTRKTLSHKLLVAEALQQL-- ---KFPLKAADLKKRIESLIDREYLARDANDANVYNYLA >Hyaloperonospora_parasitica_ABWE01000278.1| . ELVA--KFVDAKLRTG------------------NKGGTEA---EVESLLDRVMFIFRYI -QGKDVFEAFYKKDLAKRLLVGKS----------------ASFDLEKLMLSKLK------ ----------TECGSSFTNKVEGMFK---DIDLSQNVMTQFQQHA--------------- -----ASRYGSAHHCNYKTAPHCADQCRNAREALHGHHGIPDMHVQVLTT-------GFW PPYAAVE----INLPASLVPLKEIFDKFYSS-------KYQGRQLQW-QHSLAQCVVKAA FPSG-------------------------------------------------------- ------------------------------------------------KKELVVSLYQTV VLLCFNGADS-----------------------LGYKEIKEQTRIE-----DGELRRTLQ SLACGKTR--VLQKVPKS------------------------------------------ --------KDVNDDDLFEFNTHFT----NQFIRIKIN----------------------- ---SIQMKETKKENE-DTHERVFR-DRQYQVDAAIVRIMKARKKLSHALLMSEIFTQI-- ---RFPAKAADIKRRIESLIDREYLERDSTNAQVYNYLA >Glycine_max_AK286329.1| . ELLA--TFCDNILKKG-----------------GSEKLSDE---AIEETLEKVVKLLAYI -SDKDLFAEFYRKKLARRLLFDKS----------------ANDDHERSILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTLAKENQTSFEEYL--------------- -------------------------------SNNPNADPGIDLTVTVLTT-------GFW PSYKSFD----LNLPAEMVRCVEVFKEFYQT-------KTKHRKLTW-IYSLGTCNISGK FDPK-------------------------------------------------------- ------------------------------------------------TVELIVTTYQAS ALLLFNSSDR-----------------------LSYSEIMSQLNLS-----DDDVIRLLH SLSCAKYK--ILNKEPST------------------------------------------ --------KTISSTDYFEFNSKFT----DKMRRIKIP----------------------- -------LPPVDEKK-KVIEDVDK-DRRYAIDASIVRIMKSRKVLNYQQLVMECVEQLGR ---MFKPDVKAIKKRIEDLISRDYLERDKDNANLFRYLA >Pisum_sativum_AB080190.1| . ELLA--TFCDNILKKG-----------------GSEKLSDE---AIEDTFEKVVKLLAYI -SDKDLFAEFYRKKLARRLLFDKS----------------ANDDHERSILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTLAKENQTSFEEYL--------------- -------------------------------SNNPNIDPGIDLTVTVLTT-------GFG PSYKSFD----LNLPAEMVRCVEVFKEFYQT-------KTKHRKLTW-IYSLGTCNVSGK FEPK-------------------------------------------------------- ------------------------------------------------TMELVVTTYQAS ALLLFNSSDR-----------------------LSYSEIMTQLNLT-----DDDVVRLLH SLSCAKYK--ILTKEPST------------------------------------------ --------KTISPTDHFEFNSKFT----DKMRRIKIP----------------------- -------LPPVDEKK-KVIEDVDK-DRRYAIDASIVRIMKSRKVLSYQQLVMECVEQLGR ---MFKPDVKAIKKRIEDLISRDYLERDRDNANLFKYLA >Petunia_integrifolia_DQ250016.1| . ELLA--TFCDNILKKG-----------------GSEKLSDE---AIEDTLEKVVKLLAYI -SDKDLFAEFYRKKLAGGCYLIKS----------------ANDEHERSILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTLARENQASFEEYL--------------- -------------------------------SNNPAANPGIDLTVTVLTT-------GFW PSYKSFD----LQPPTEMVRCVEVFKEFYQT-------KTKHRKLTW-IYSLGTCNINGK FDPK-------------------------------------------------------- ------------------------------------------------TIELVVTTYQAS ALLLFNASDR-----------------------LSYQEIMAQLNLS-----DDDVVRLLH SLSCAKYK--ILNKEPST------------------------------------------ --------KTISQTDVFEFNSKFT----DKMRRIKIP----------------------- -------LPPVDEKK-KVIEDVDK-DRRYAIDASIVRIMKSRKVLGYQELVMECVEQLGR ---MFKPDVKAIKKRIEDLITRDYLERDKDNPNLFKYLA >Nicotiana_tabacum_AJ344535.1| . ELLA--TFCDNILKKG-----------------GSEKLSDE---AIEETLEKVVKLLAYI -SDKDLFAEFYRKKLARRLLFDKS----------------ANDEHERSILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTLARENQASFEEYL--------------- -------------------------------SNNPAANPGIDLTVTVLTT-------GFW PSYKSFD----LNLPAEMVRCVEVFKEFYQT-------KTKHRKLTW-IYSLGTCNINGK FEPK-------------------------------------------------------- ------------------------------------------------TIELVVTTYQAS ALLLFNASDR-----------------------LSYQEIMTQLNLS-----DDDVVRLLH SLSCAKYK--ILFKEPST------------------------------------------ --------KTISPTDVFEFNSRFA----DKMRRIKIP----------------------- -------LPPEDEKK-KVIEDVDK-DRRYAIDASIVRIMKSRKVLGYQQLVMECVEQLGR ---MFKPDVKAIKKRIEDLITRDYLERDKDNPNLFKYLA >Lycopersicon_esculentum_BT013673.1 . ELLA--TFCDNILKKG-----------------GSEKLSDE---AIEETLEKVVKLLAYI -SDKDLFAEFYRKKLARRLLFDKS----------------ANDEHERSILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTLARENQASFEEYL--------------- -------------------------------SNNPIANPGIDLTVTVLTT-------GFW PSYKSFD----LNLPAEMVRCVEVFKEFYQT-------KTKHRKLTW-IYSLGTCNINGK FEPK-------------------------------------------------------- ------------------------------------------------TIELVVTTYQAS ALLLFNASDR-----------------------LSYQEIMTQLNLS-----DDDVVRLLH SLSCAKYK--ILNKEPST------------------------------------------ --------KTISPTDVFEFNSKFT----DKMRRIKIP----------------------- -------LPPVDEKK-KVIEDVDK-DRRYAIDASIVRIMKSRKVLGYQQLVMECVEQLGR ---MFKPDVKAIKKRIEDLITRDYLERDKDNPNLFKYLA >Oryza_sativa_XM_467770.1| . EFIS--LYVDDKLRKG------------------LKGATEE---DVEVILDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAERSMIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSQDTMIDFYAKK--------------- ---------------------------------SEELGDGPTLDVHILTT-------GSW PTQPCPP----CNLPTEILAICDKFRTYYLG-------THSGRRLTW-QTNMGTADIKAT FGKGQ------------------------------------------------------- ------------------------------------------------KHELNVSTYQMC VLMLFNSTDG-----------------------LTYKDIEQDTAIP-----ASDLKRCLQ SLACVKGKN-VLRKEPMS------------------------------------------ --------KDISEDDTFYFNDKFT----SKLVKVKIG----------------------- -TVVAQ-KESEPEKQ-ETRQRVEE-DRKPQIEAAIVRIMKSRRVLDHNSIVAEVTKQLQA ---RFMPNPVVIKKRIESLIEREFLERDKADRKLYRYLA >Hordeum_vulgare_AK252660.1| . EFIS--LYVDDKLRKG------------------LKGATEE---DVEGILDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAERSMIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSQDTMQDFYAKK--------------- ---------------------------------SEELGDGPTLDVHILTT-------GSW PTQPSPP----WSLPPEILTVCEKFRGYYLG-------THSGRRLTW-QTNMGTADIKAT FGKSQ------------------------------------------------------- ------------------------------------------------KHELNVSTYQMC VLMLFNTSDG-----------------------LTYKDIEQATEIP-----STDLKRCLQ SLACVKGKN-VLRKEPMS------------------------------------------ --------KDISEDDTFFFNDKFT----SKLVKVKIG----------------------- -TVVAA-KESEPEKQ-ETRQRVEE-DRKPQIEAAIVRIMKSRRVLDHNSIVSEVTKQLQA ---RFLPNPVIIKKRIEELIEREFLERDKADRKLYRYLA >Physcomitrella_patens_XM_001758222.1| . EFIS--LFVDDKLRKG------------------LKGVSEE---DVELVLDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGRT----------------VSDDAERSLIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSRDTMQGFNATS--------------- --------------------------------AGTEGNEGPTLTVQVLTT-------GSW PTQSGAR----CNMPTEILAMCDKFKMYYLS-------THTGRRLTW-QTNMGTADLKAT FGDGN------------------------------------------------------- ------------------------------------------------KHELNVSTYQMC ILYLFNQADR-----------------------LTYKEIEQATDIP-----ALDLKRSLQ SLACVKGKN-VLRKEPMS------------------------------------------ --------KDISEDDVFVFNDKFS----SKFYKVKIS----------------------- -TVVAQ-KESEPEKQ-ETRQKVEE-DRKPQIEAAIVRIMKSRRLLDHNNIISEVTKQLQA ---RFMPNPAVIKKRIESLIEREFLERDRVDRKLYRYLA >Leishmania_major_XM_001683831.1| . -----------------------------------TEVR-----EATSVLRRIAHIYSYH -PKKDLFEAAYWRDFARRCLHAHR---------------KLNSAPENTFIGFLR------ ----------DICGLSFTSKFEGMLT---DLTSSTELTTQYNTWVQEQE----------- -------------QQQQQQPSGEAGVDTAAVGRLVSEAKGLDAHLFILTQ-------SYW PECPSMP--GNFYVPPALRAVTQLVEKFYTG-------RFPNRHLSW-QHPLSHATLLVR LTPQSS------------------------------------------------------ ------------------------------------------------VLTLTGTYTQCV LLMQLDALYDRG------------------VTTITAKALCDAVGMD---MTNTELLWSLQ GLCHPRFRL-VLRAEAASSPPSGGGAQRKSAELDNEDDESAARVEESAASCTSPQSVSPG AAAGASAGCTLAATDLLQLNLSFT----SATSKVRIPFQTR------------------- ---MRTTASAGLDGP-SRGGRTAD-NGGHLVEVAIVSCLKSQRTMTRTDLASAVAARV-- ---PFPVTTTVLKKAIDKLIERGFMIRGKGS--TYVY-- >Leishmania_infantum_XM_001466126.1| . ------------------------------------------------VLRRIAHIYSYH -PKKDLFEAAYWRDFARRCLHAHR---------------KLNSTAENTFIGFLR------ ----------DICGLSFTSKFEGMLT---DLTSSTELTTQYNTWVQEQERSL-------- -------------QQQQQQPSGEEGAETSAVGRLVPEAKSLDAHLFILTQ-------SYW PECPSMP--SNFYVPPAVRAITQLVEKFYTG-------RFPNRHLSW-QHPLSHATLVVR LTPQSS------------------------------------------------------ ------------------------------------------------TLTLTGTYTQCV LLMQLDALYDRG------------------VTSITAKALCDAVGMD---IANTELLGSLQ GLCHPRFRL-VLRAEAASSPPSGDGAQRTSAELDNEDDESAARVEEAAASCASPQSSSPG TAAGASAGCTLAATDLLQLNLGFT----SATSKVRIPFQTR------------------- ---MRTTASAGLDGP-SRGGRTAD-NGGHLVEVAIVSCLKAQRTMTRIDLASAVAARV-- ---PFPVTTAVLKKAIDKMIERGFMVRGKDN--AYVY-- >Leishmania_braziliensis_XM_001565578.1| . -----------------------------------AEVK-----EVTSVLRRIAHIYSYH -PKKNMFEDAYWRDFARRCLHAHR---------------KLNSTVENAFICFLR------ ----------DICGLSFTSKFEGMLT---DLTSSAELTTQYSMWVQEQEQP--------- --------------------SGEKGGGAAAMGHSMSGTKSLDAHLFILTK-------SYW PEYPPMP--SSFYVPPAVQAVTQQVEKFYTG-------LFPNRHLSW-QYPLSHATLLTR LTPQSS------------------------------------------------------ ------------------------------------------------VLTLTGTYTQCV LLMRLDALYDRG------------------VTSITAKALCDAVGMD---MANAEFLWSLQ GLCHPRFAL-VLRKGVGSLVSAAGGAQCKSVELDNEDDESGARVEGVVGTSASPQSASSG AAAGASASYAITATDSLQLNLSFT----SAKSKVRIPLQTR------------------- ---MRAMASVGFDGL-SRGGRTAD-NGGHLVEVSIVSCLKAQRTVTRADLASAVAAQV-- ---PFPVTTAVLKKAIDKMIERGFMVRGKDS--TYVY-- >Trypanosoma_brucei_CP000066.1 . DWVV--RGSDTSTALGQSDHSESKP-----MATADGSSDVG---GVLKLLDDIGRIYSLF -PSKDIFEKLYWRDLARRLLHHPR--------------GTPCVDVEGHFIQILR------ ----------EIVG-TDAAKFEGMVN---DLMSSQELNERFRLWVVNKHTEVPPLSPPPT SVANEEDDQTETPQPKAQHNNEGYEEEEENHEAVEAALAAVDVKLNVLTD-------GYW PKQTPLS----TELPPQLRVLAKSMEVFYRK-------CFAKRRLIW-LHQLSSAVVKSA VGNS-------------------------------------------------------- ------------------------------------------------RRQLSGTLVQAN VLLALQEIIDAGMHSE--------------QLCVSVGEICGQLGLD---ISLPDVVGAIL GLCHPKFR--LLLRAPGSGTDGSNQHGSDDASGYGSSVG--------------------- -----VVAATLLGTDILRINHSFS----VPSQFCRIPFLGARRRGGDG------------ ---AVDERAADTDGE-QTMEDIMK-DRVHVVDAAIVRLMKQRRRASHEEVMEEVPKLV-- ---RFPVTASAVKESARRLTERGFLERGNT--NEYIYIS >Trypanosoma_cruzi_XM_800380.1| . ------------------------------------------------LLNYIGRIYALL -PSRGIFETFYWHDLARRLLQYQR---------------PRRLDAERSFIQELK------ ----------KTCG-VETSKFEGMFN---DLKVSQELNERYQAWVTGKRD---------- --------DTSAQWPPVMRVDNEEEEEE-AMSLIAEFPWNTEVKLHILTS-------GFW PTQSTLA----VRLPSPMRLLAKCVQDFYRQ-------CFTDRQLVW-QHQLSSAVVRCS MGTVR------------------------------------------------------- -------------------------------------------------RNLMGTLLQAA ILLTLQEMMDTTPSSSSSQR----------VEAVTVGALCDRLAVD---ISIPAVSGAIY GLCHPKFS--LLLREPATGGPSA------------------------------------- -----TALSMLAGTDRLRFNTHFA----VSSMRCRIPFYNTPNSGED------------- ----VSTGRNDADSM-LAVDDVLK-EHKHVIEAAVVRFMKEKRCATHEDLVTAVSTLV-- ---QFPVTMATLKCVIERLIDRGFLERNGAT--AYTY-- >Trypanosoma_cruzi_XM_801591.1| . ------GGSDEVAAAAT-----------------ATATAVS---PCGGLLNYIGRIYALL -PSRGIFETFYWHDLARRLLQYQR---------------PRRLDAERSFIQELK------ ----------KACG-VETSKFEGMFN---DLKVSQELNERYQAWVTGERD---------- --------DASAQWPPVMRVDNEEEEEGEAMSLIAELPWNTEVKLHILTS-------GFW PTQSTLA----VRLPSPMRLLAKSVQDFYRQ-------CFTDRQLLW-QHQLSSAVVRCS IGTVR------------------------------------------------------- -------------------------------------------------RNLTGTLLQAA ILLTLQEMMDTTPSSSSSQR----------VEAVTVGALCDRLAVD---ILVPAVTGSIY GLCHPKFS--LLLREPAMGGSSA------------------------------------- -----AAFPMLAGTDRLRFNTHFA----VSSMRCRIPFYNTPNSGED------------- ----VSTGRNDADSM-LAVDDVLK-EHKHVIEAAVVRFMKEKRCATHEDLVTAVSTLV-- ---QFPVTMATLKCVIERLIDRGFLERNGAT--AYTY-- >Trypanosoma_brucei_CP000071.1 . -LVA--VYCDVLVSQSGTRGVAVTADKETEIGGKCVSLPEGS--DSTSDIDSVTALAALL -DDKDVFLEEYKQLLARRLIILSSSLSLSPSALPTELCTKPNAEYEHAMIRELR------ ----------RTFGRTSTLTLKMMLH---DYTLSCAMGSAFRQTP--------------- ----------------------------------SAQQLKSGINVQVITG-------ARW PTYSTVP----LLPCTSLAAAISTFSTYYAA-------AHPLRTLSW-IHSQGTANLEAL FPNG-------------------------------------------------------- ------------------------------------------------SKEIVADTIQSN ILILLSDAYNTVRRNRDSESRRGVGEGKSTKRYLTGQEIASAMGMS-----FENLYAYLN QLVHHTSYK-LITRVPSPNPDPAVDPN--------------------------------- -------EASVRPEYGYTINVDFK--HSSNSFRLPVPHPRWNQKASGGHR---------- ----VVGADAMAASQ-TFALVTES-TRRLQVDAAIVRTMKRHRSLPYHELMSTTVQELSR ---FFVPSTQFVKVQVEGLIAREFLKRNEANSQLLEYVV >Leishmania_major_CT005272.1| . ETLS--VYYDNGIRQG-------------------KDD------IVSTVGNNVLTILQLT -PDLEAFEVAFRSHLAVRLIYAKP----------------HAVNMECLFIDRLF------ ----------NIYGSSVVNRFQKMVE---DIRSATAAQEKLIADM--------------- --------------------------------KTKRISPPLEFNVLVLTS-------GLW PQYTNIP----LSIPQSMEACKRVFQEYYRR-------RHNGRKLVF-QMSLGSIAFQLC HGDR-------------------------------------------------------- ------------------------------------------------TYHVSAHTHFVN SIMALNSDEN-----------------------LSVAVVAQQGALS-----CDEVLTQFN TLCHVG----LAER---------------------------------------------- ------------NGTEFRFNRNFY----SSKPKVKVSAGVQ------------------- ----KSAHDGGSASA-ATRKGMDG-ARTMSLDATIVKLLKEHNSMDYQTLCGAIESELRD ---VCSPTRTDVKLRIDALIEKGLMTRGESA-HCYFYCS >Leishmania_donovani_DQ418548.1| . ETLS--VYYDNGIRQG-------------------KDD------IVSTVGNNVLTILQLT -PDLEAFEVAFRSHLAVRLIYAKP----------------HAVDMECLFIDRLF------ ----------NIYGSSVVNRFQKMVE---DIRSATAAQEKLIADM--------------- --------------------------------KTKKISPPLEFDVLVLTS-------GLW PQYTNIP----LSIPQSMEACKRVFQDYYRR-------RHNGRKLVF-QMSLGSIAFQLC HAGR-------------------------------------------------------- ------------------------------------------------AYHVSAHTHFVN SIMALNSDEN-----------------------LSVAVVARQGALS-----CDEVLTQFN TLCHVG----LAER---------------------------------------------- ------------NGTEFRFNRNFY----SSKPKVKVSAGVQ------------------- ----KSAHDGGGAST-ATRKGMDG-ARTMSLDATIVKLLKEHNSMDYQTLCGAIESALRD ---VCSPTRADVKLRIDALIEKGLITRGESA-HCYFYCS >Leishmania_braziliensis_XM_001568897.1| . ETLS--VYYDNGIRQG-------------------KDD------VVSTVGNNVLTILQLT -PDLEAFEVAFRSHLAVRLIYAKP----------------HAVDMECRFIDRLF------ ----------NIYGSSVVNRFQKMVE---DIRSATAAQEKLVADM--------------- --------------------------------KTKKISPPLEFDVLVLTS-------GLW PQYTNIP----LSIPQSMESCKHVFQEYYRR-------RHNGRKLVF-QMSLGSIAFQLC HGGR-------------------------------------------------------- ------------------------------------------------TYHVSAHTHFVN SIMALNSDED-----------------------VSVAVVARQGALS-----SDEVLTHFN TLCHVG----LAER---------------------------------------------- ------------NGTEFRFNRRFY----SSKSKVKVSAGVQ------------------- ----KSAHDGSGGAI-AACKGMDG-ARTMSLDATIVKLLKEHNSIDYHTLCCAIESELRG ---VCSPTRTDIKLRVDALMEKGLLMRGESA-NCYVYCS >Trypanosoma_brucei_XM_817890.1| . -----------------------------------THD------SMDQVAADTFSLYRLL -RSKESFEQTFKLLLAARLINCKP---------------NDSLVHEIIFVEHLR------ ----------SECGDSVANHLDVMIK---DGRMRTEINRGFLSSL--------------- ---------------------------------SPDVQLPLSFDVTVITA-------GVW PIYPGFE----INLPECMQQCVSLFQAYYIP-------HHNGRVLSF---HTGCGTICFT LNHK-------------------------------------------------------- -----------------------------------------------EVYELAAPTSFVN TILCFQSCGGIDEP-------------------LTVKDICNKTKMI-----ETDVLPQLE ALVNTG----LISNVPSG------------------------------------------ ------------GLSRFIFNKHFA----HHRTKLRIGNVGG------------------- ----NRTVKASAEVR-VTQVASET-THAESIQAVLMQIVKRNKTLSHGEMFTQVAEALKG S--RITPVMAHIKQNLEILINKGLISRGSRP-DIYVYEA >Trypanosoma_cruzi_XM_808353.1| . EKLA--YYYDAKVKSK---------------------ISEA---ELERLVADVFGLFRLL -RTKEVFDHAFKLLLAARLINSKP---------------EDPLSNETFLIDQIR------ ----------NECG-ESANHLEIMIK---DGRMRREMNKGFIRSL--------------- ---------------------------------GTGNKLPHEFYVTVITA-------GVW PEYTDLA----PDLPESMQNCMQLFRSYYLP-------HHNGRKLSF-NTTLGTVFFTLN HGKI-------------------------------------------------------- -------------------------------------------------YELVAPTAFAS TILCFQNSDQNNE-------------------YLSLQEICDKTKLI-----ERDASFQLE SLSQLG----LITVDRVD------------------------------------------ ------------DVLRYAFNQAFD----NPRSKLRVRATSG------------------- ----NRILEKNRETR-AHCEPLGA-SISFSIQAAAIQIIKSKKKIGHTEFCNAITKSLQK A--GFAPSVADIKKGLETLMSKGLLSRKNS--NIYIY-- >Trypanosoma_cruzi_XM_814790.1| . ENLA--YYYDAKVKSK---------------------ISEA---ELERLVADVFGLFRLL -KTKEVFDHAFKLLLAARLINSKP---------------EDPLSNETFLIDQIR------ ----------NECG-ESVNHLEIMIK---DGRMRREMNKGFIRSL--------------- ---------------------------------GTGNKLPHEFYVTVITA-------GVW PEYTDLA----PDLPESMQNCMQLFCSYYLP-------HHNGRKLSF-NTTLGTVFFTLN HGKI-------------------------------------------------------- -------------------------------------------------YEIVAPTAFAS TILCFQNSEQNNE-------------------YLSLQEICDKTKLI-----ERDASFQLE SLSQLG----LITVDRVD------------------------------------------ ------------DVLRYAFNQAFN----NPRSKLRVRTTNG------------------- ----NRILEKNRETR-AYCEPLGD-SISFSIQAAAIQIIKSKKKIGHTEFCNAITKSLQT A--GFVPSVADIKKGLETLMSKGLISRGGNS-NIYIY-- >Cyanidioschyzon_merolae_AP006495.2| . EFLS--LYIDKALRES-------------------PSISRE---ATRAALEHASGLFRLL -RNKDVFEQHYKVHLSRRLLRRFA--------SNTVVPPSANDDAEQHFISKLR------ ----------EECGAVYTAKLEAILQ---DMRTSDELNAAYRRHQ--------------- -----------------------------EMIQLYGSRARPMLQVCVITN-------GIW PVAEAPT-AQIPACHPELVEITQEYEKFYHE-------RHAKRRLQW-LLHQGSAELCMR LSDEGP------------------------------------------------------ ------------------------------------------------ALSLKVTSLQML ILLLFNNAEA-----------------------LTVQEMLRLLQFP---GLSPELMRALR ALCDSRHA--ILVRAANG------------------------------------------ --------PVICNRDVFRVNKAFQ----STTLDIDLTDTD-------------------- ----HVDENAGVERAARSSELLER-DRRPEITACVMRILKRRQELEHSQLVAQVIDELHN ---RFVPTVAEVKREIEALLEREYIARESDELTVYRYI- >Cyanidioschyzon_merolae_AP006496.2| . ERLA-RSFHD-LLRVS------------------STSIPEP---DIRRKIGKLLELFRYL -SGKDSFLAFYKKYLAQRLLFDLT----------------ASTACEQYVVELLR------ ----------AECGAVYVNHLVNMLK---DMDLSQDLLQEYRMGP--------------- ---------------------------------GSGSSRLPSFTCKVITQ-------AYW NSSESFL----LQVPPGLESQQRSFHRFYHA-------RFSGRRLIW-EPSLSSAELRVQ FANG-------------------------------------------------------- ------------------------------------------------EKVLHVTLSQAV VLLLFNERDA-----------------------WTLAELQQQTGIA----DSAELERILD SLSSSQCP--VLIRERGAEAAS-------------------------------------- -------SGPVTAPARYRFNADLQ----TSRRRLRLLD---------------------- ----IALLERPPEQV-PSGPVASP-DRQHQIDAAIVRLLKKQKSLSHADLVQQLGAEL-- ---CFGPSVSDVKQRVESLLQREYIGRDERDPNLYHYVS >Trypanosoma_cruzi_XM_800835.1| . YLLHG-SHEEAEVRRVG-------------GGGRAKTVVVS--LHNEDEVMSAVRLAFSV -SSIDRFLRLYKELLAYRLLFYAVG-RARDGSVDAMEARREKLQTEKLVCKYLH------ -----------ELLPLERNAIQQMIQMCMDMETGKNAPEGYDPQA--------------- --------------------------LQPEQCGHGAETVTVRPTLRLLSR-------LAW PSYPLLT-----DVPQPLHNAMDQFARFYHA-------QYSNRRVVWLRTSMETITFTVA YPQAG------------------------------------------------------- --------------------------------------------------KVIVGSLELF NIFQFLSEAGTSG--------------------TTWTLLAQRIGKD-----KTLLQRGLK KLIHDG-----FFKIQMG------------------------------------------ -----------SGEESVALNAAFK----SHKPRYNFLQPP-------------------- ----PRVGALLEENG-IINEEVHR-SRIASIQAVIIKHMKSVRTCLYDELFC-WTRQQNP ---QFQLQNSDFKLALEMLIEKEFVQRDPSQKQRFVYKA >Trypanosoma_cruzi_XM_806457.1| . YLLYG-SHEGAEVRRVG-------------GGGREKMVLVS--LHNEDEVMSAVRLAFSV -SSIDRFLRLYKELLAYRLLFYAVG-RASDGSVDAMEARREKLQTEKLVCEYLH------ -----------ELLPFERNAIQQMIQMCMDMVTGNNTPEAYDPQA--------------- --------------------------LQPEQCGHGADAFSVRPTMRLLSR-------LAW PSYPLLT-----DVPKPLHNVMDQFARFYHA-------QYSNRRVVWLRTSMETITFTVA YPQAG------------------------------------------------------- --------------------------------------------------KVIVGSLELF NIFHFLSEAGTSG--------------------TTWTLLAQRIGKD-----KTLLQRGLK KLIHDG-----FFKIQMG------------------------------------------ -----------SGEEIVALNAAFK----SHKPRYHFLQPP-------------------- ----PRVGALLEENG-IINEEVHR-SRIASIQAVIIKHMKTVRTCLYDELFC-WTRQQNP ---QFQLQNSDFKLALEMLIEKEFVQRDPSQKQRFVYKA >Trypanosoma_brucei_AC087327.7 . -------YLLRGNETSP-----------------ATGNGSL---SGNEDLRAALRIIQGL -SGRTQLFSFYKENLAIRLLSILHP-KPHDNAVSTEELRHERLQFEGSMCRYLM------ --------ELFPGDREAVQHMVQMCE---DVKTANEMSEAFNQQQ--------------- ------------------------------MQDIGNAALSVKLTTSILSP-------HAW PVYPKLE-----RVPRPLKNTMDGFSAFYQN-------RHSTRRLIW-IRTTFERVTFDI AYP--------------------------------------------------------- ------------------------------------------------RGKKLVT-GSLE HYEIFNCLSEAAGAG------------------VTWENLAKEVEWE-----TAKLQQELR KPIFNG----LLVLPQEEEAKVAER----------------------------------- --------ADTASQQALRLNPEFT-SSHTHFNLLPERSQR-------------------- ----KQLTTCTRTNE-KAAKGLQE-TRIGAIQAAVMHRLKTVQHGSYKDLFQFTQESLRH ---HFQLSDVEFKEVLRRLIDKEYIVRDQEDREQFVYRA >Leishmania_infantum_XM_001470215.1| . ----------------------------------IKSMPID---ELRRTNNWIAVIYRLC -TRQDVFHLSYTRFLQERLLTNIF----------GTVKQSEIAVREESMLSSLL------ ---------------IKDKNFAFIFN---CMRMLNDARRNDSKRA--------------- -----------------------------------ERVQELLVKPYILTA-------FAW GESRRSSDMGRSSVPFELQSVISHDIDAYSA-------LQNGRKLLF-SPEHSGARVRMS VSNK-------------------------------------------------------- ----------------------------------------------AASFSLLVSLLQMR YLLVMNKMSE-----------------------WSADELCSQTRTS-----LEECKRALT PFVQTG----LLQETAQH------------------------------------------ --------VFNLDPNILALQSGEEK--MYDLRYIELG----------------------- ------SQQSNPEKN-SFFLRGEK-SHVLSIEGAVMRLLKELGPLSLDVIISKVSASLG- ---KLSVQRRDIKKVLEKLVEREYVERSEDN-------- >Leishmania_braziliensis_XM_001566209.1| . -----------------------------------KSMPVE---ELRLKSNWIAVIYRLC -SRQDVFHQSYTRFLQERLLKNIF----------GTGKQSEIAVREESILSSLL------ ---------------IKDRNFAFIFN---CMRMLNDTYRNDLKQA--------------- -----------------------------------KRVQQFLVKPYILTA-------FPW GESRRSPDADRTSVPLELQTVISHDIDAYAA-------LQNGRRLLF-SPEHSGARVKMS IPNKS------------------------------------------------------- -----------------------------------------------VSLSVLVSFLQMR YLLVMNKMSV-----------------------WSADVLCSRTCTS-----LEECKRALI PFVQTG----LLQEAVQH------------------------------------------ --------VFDLNPNIFALQNGEEK--TYDLRYIELG----------------------- ------SQQSNPEKN-SFFLRGEK-SHVLSIEGAVMRVLKELGPLSLDDTIGKVSASLG- ---KLSVQRRDIKKVLEKLVEREYVERSEDN-------- >Leishmania_major_CT005266.1| . ----------------------------------IKSMPID---ELRRTNNWIAVIYRLC -SRQDVYHLSYTRFLQERLLTNIF----------GTGKQSEIAVREESMLSSLL------ ---------------IKDKNFAFIFN---CMRMLNDARRNDSKRA--------------- -----------------------------------ERVQQLLVKPYILTA-------FAW GESRRSPDMGRTSVPLELQSVITHDIDAYSA-------LRNGRKLLF-SPEHSGARVRMS VSNK-------------------------------------------------------- ----------------------------------------------AASFLLLVSLLQMR YLLVMNKMSE-----------------------WSADELCSQTRTS-----LEECKRALT PFVQTG----LLQETAQH------------------------------------------ --------VFKLDPNIFALQSGEEK--MYDLRYIELG----------------------- ------SQQSNPEKN-TLFLRGEK-SHVLSIEGAVMRLLKELGPLSLDVIIGKVSASLG- ---KLSVQRRDIKKVLEKLVEREYVERSEDN-------- >Physcomitrella_patens_XM_001781728.1| . EFIS--LFVDDKLRKG------------------LKGASEE---DVELVLDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGRT----------------VSDDAERSLIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSRDTMQGFNATG--------------- --------------------------------AGAEGNEGPTLTVQVLTT-------GSW PTQSGAR----CNMPTEILAMCDKFKMYYLS-------THTGRRLTW-QTNMGTADLKAT FGDGN------------------------------------------------------- ------------------------------------------------KHELNVSTYQMC ILCLFNQADR-----------------------LSYREIEQATDIP-----APDLKRSLQ SLACVKGKN-VLRKEPMS------------------------------------------ --------KDISEDDTFVFNDKFS----SKFYKVKIS----------------------- -TVVAQ-KESEPEKQ-ETRQKVEE-DRKPQIEAAIVRIMKSRRLLDHNNIISEVTKQLQA ---RFMPNPAVIKKRIESLIEREFLERDRMDRKLYRYLA >Picea_sitchensis_EF677486.1| . EFIS--LFVDDKLRKG------------------LKGVNEE---DVEVVLDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAERSLIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSRDTMQGFTSML--------------- -------------------------------AASSEGNEGPTLAVQVLTT-------GSW PTQTGAR----CNLPKEILAVCDKFKAYYLS-------THTGRRLTW-QTNMGTADLKAT FGKGQ------------------------------------------------------- ------------------------------------------------KHELNVSTYQMC ILILFNSADR-----------------------LSYRDIEEATDIP-----APDLKRCLQ SLACVKGRN-VLGKEPMS------------------------------------------ --------KDIGEEDDFYFNEKFS----SKFYKVKIG----------------------- -TVAAQ-KETEPEKQ-ETRQRVEE-DRKPQIEAAIVRIMKARRVLDHNNIVAEVTKQLQS ---RFLPNPAVIKKRIESLIEREFLERDKTDRKLYRYLA >Lotus_japonicus_BABK01035245.1| . EFIS--LFVDDKLRRG------------------LKGVGEE---DVEIILDKVMMLFRFL -QEKDIFEKYYKQHLAKRLLSGKT----------------VSDEAERSLIVKLK------ ----------TECGYQFTSKLESMFT---DMKTSHDTTHGFYASH--------------- ---------------------------------GPELGDGPTLSIQVLTT-------GSW PTQPSPQ----CNLPTEILGVCDKFRAYYLG-------THSGRRLSW-QTNMGTADLKAT FGKGQ------------------------------------------------------- ------------------------------------------------KHELNVSTFQMC VLMLFNNADR-----------------------LTCKEIEQATAIP-----MSDLKRCLQ SLACVKGKN-VLRKEPMS------------------------------------------ --------KDIAEDDAFLFNDKFT----SKFFKVKIG----------------------- -TVVAQ-RESEPENL-ETRQRVEE-DRKPQIEAAIVRIMKSRRTLDHNNVVAEVTKQLQS ---RFLPNPVVIKKRIESLIEREFLERDKVDRKMY---- >Vitis_vinifera_AM478489.2| . EFIS--LFVDDKLRKG------------------LKGVSEE---DVEIVLDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAERSLIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSEDTMQGFYASS--------------- ---------------------------------FAETGDGPTLAVQVLTT-------GSW PTQPSAT----CNLPAEILGVCEKFRGYYLG-------THTGRRLSW-QTNMGTADLKAT FGRGQ------------------------------------------------------- ------------------------------------------------KHELNVSTHQMC ALMLFNNADR-----------------------LSYKEIEQATEIP-----ASDLKRCLQ SMACVKGKN-ILRKEPMS------------------------------------------ --------KDIAEDDAFFVNDKFS----SKFYKVKIG----------------------- -TVVAQ-RESEPENQ-ETRQRVEE-DRKPQIEAAIVRIMKSRRVLDHNNIVAEVTKQLQS ---RFLPSPVLIKKRIESLIEREFLERDKVDRKLYRYLA >Lycopersicon_esculentum_AC122544.1| . EFIS--LFVDDKLRKG------------------LKGVTEE---DVEIILDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAERSLIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSQDTMQGFHAAV--------------- ---------------------------------GADLAEGPSLTVQVLTT-------GSW PTQSVNT----CNLPSEILGVCDRFKTYYLG-------THTGRRLSW-QTNMGTADLKAT FGKGQ------------------------------------------------------- ------------------------------------------------KHELNVSTYQMC ILMLFNKSDR-----------------------MSYKEIEQATEIP-----ASDLKRCLQ SLACVKGKN-VLRKEPMS------------------------------------------ --------KDIAEDDAFYFNDKFS----SKFYKVKIG----------------------- -TVVAQ-KESEPEKQ-ETRQRVEE-DRKPQIEAAIVRIMKSRRVLDHNNIVAEVTKQLQS ---RFLPNPVVIKKRIESLIEREFLERDKTDRKLYRYLA >Lotus_japonicus_AP010023.1| . EFIS--LFVDDKLRKG------------------LKGVSED---DIETTLDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAERSLIVKLK------ ----------TECGYQFTSKLEGMFT---DMRTSVDTMQGFYASH--------------- ----------------------------------PELGDGPTLTVQVLTT-------GSW PTQSSLT----CNLPAEMSALCEKFRSYYLG-------THTGRRLTW-QTNMGTADLKAT FGKGQ------------------------------------------------------- ------------------------------------------------RHELNVSTYQMC VLMLFNNAER-----------------------LTYKEIEQATEIP-----ASDLKRCLQ SLALVKGRN-VLRKEPMS------------------------------------------ --------KDVGEDDAFFVNDKFS----SKLYKVKIG----------------------- -TVVAQ-KESEPEKL-ETRQRVEE-DRKPQIEAALVRIMKSRKQLDHNNLIAEVTKQLQS ---RFLANPTEVKKRIESLIEREFLERDDVDRKLYRYLA >Phytophthora_capsici_BT031945.1| . ----------------------------------LSSQLDD---MLEQKIENISVVFCLI -DDKDIFKKFYSKFLAKRLIKGTS----------------ASNDMEILLIQKLR------ ----------DICGCDFVSKLQKMLK---DKMLSKELMGSFTAWL--------------- -----------------EEKDIDLRSESAANSLAIELHHGVAYHCDVLTA-------GAW PISSAAA-ELKIFLPPAIEAHTKLFTQFYTG-------RSTGRKLLW-IHHLSYGMIQSH CFTK-------------------------------------------------------- ------------------------------------------------RYEFLLSFYQLL ILVQFNTATT-----------------------IQRSEIIQRTNIP-----EQDCTHHLA SLVKAK----ILTSDGD------------------------------------------- -----------AVNPMYAINFGFS----SRKLRVSAI----------------------- ---PNSPVESPKAVK-VPTREVEE-DRKMSLQAAIVRVLKTRRDIRQAQLMHEVAEILVN ---QFVPSTTTIKQNVEILIQKEYLRRHEDDKTRFLYVA >Medicago_truncatula_AC146568.11 . EFIS--LFVDDKLRKG------------------LKGVNED---DVEVTLDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAERSLIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSQDTMQGFYASH--------------- ----------------------------------PDLGDGPTLTVQVLTT-------GSW PTQSSIT----CNLPVEISALCEKFRSYYLG-------THTGRRLSW-QTNMGFADLKAT FGKGQ------------------------------------------------------- ------------------------------------------------KHELNVSTYQMC VLMLFNNADK-----------------------LSYKEIEQATEIP-----APDLKRCLQ SLALVKGRN-VLRKEPMS------------------------------------------ --------KDVGEDDAFSVNDKFS----SKLYKVKIG----------------------- -TVVAQ-KESEPEKQ-ETRQRVEE-DRKPQIEAAIVRIMKSRRLLDHNNLIAEVTKQLQL ---RFLANPTEVKKRIESLIERDFLERDDNDRKMYRYLA >Brassica_rapa_AC189408.2| . EFIS--LFVDDKLRKG------------------LKGIADA---DVEVVLDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAEKSLIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSEDTMRGFYGSH--------------- ----------------------------------PELSEGPTLIVQVLTT-------GSW PTQPAVP----CNLPAEVSVLCEKFRSYYLG-------THTGRRLSW-QTNMGTADIKAI FGKGQ------------------------------------------------------- ------------------------------------------------KHELNVSTFQMC VLMLFNNSDR-----------------------LSYKEIEQATEIP-----APDLKRCLQ SLACVKGKN-VIKKEPMS------------------------------------------ --------KDIGEEDLFCVNDKFT----SKFYKVKIG----------------------- -TVVAQ-KETEPEKQ-ETRQRVEE-DRKPQIEAAIVRIMKSRKILDHNNIIAEVTKQLQP ---RFLANPTEIKKRIESLIERDFLERDNTDRKLYRYLA >Arabidopsis_thaliana_AJ344252.1_cul3a| . EFIS--LFVDDKLRKG------------------LKGITDV---DVEVILDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAERSLIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSEDTMRGFYGSH--------------- ----------------------------------PELSEGPTLIVQVLTT-------GSW PTQPAVP----CNLPAEVSVLCEKFRSYYLG-------THTGRRLSW-QTNMGTADIKAI FGKGQ------------------------------------------------------- ------------------------------------------------KHELNVSTFQMC VLMLFNNSDR-----------------------LSYKEIEQATEIP-----AADLKRCLQ SLACVKGKN-VIKKEPMS------------------------------------------ --------KDIGEEDLFVVNDKFT----SKFYKVKIG----------------------- -TVVAQ-KETEPEKQ-ETRQRVEE-DRKPQIEAAIVRIMKSRKILDHNNIIAEVTKQLQP ---RFLANPTEIKKRIESLIERDFLERDSTDRKLYRYLA >Brassica_rapa_AC189385.2| . EFIS--LFVDDKLRKG------------------LKGIADV---DVEVILDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAEKSLIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSEDTMRGFYGSH--------------- ----------------------------------PELSEGPSLTVQVLTT-------GSW PTQPAVP----CNLPAEVSVLCEKFRSYYLG-------THTGRRLSW-QTNMGTADIKAV FGKGQ------------------------------------------------------- ------------------------------------------------KHELNVSTFQMC VLMLFNNSDR-----------------------LSYKEIEQATEIP-----APELKRCLQ SLACVKGKN-VIKKEPMS------------------------------------------ --------KDIGEDDLFVVNDKFT----SKFYKVKIG----------------------- -TVVAQ-KETEPEKQ-ETRQRVEE-DRKPQIEAAIVRIMKSRKILDHNNIIAEVTKQLQP ---RFLANPTEIKKRIESLIERDFLERDNTDRKLYRYLA >Arabidopsis_thaliana_NM_105635_Cul3b| . EFIS--LFVDDKLRKG------------------LKGVGEE---DVDLILDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAERNLIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSHDTLLGFYNSH--------------- ----------------------------------PELSEGPTLVVQVLTT-------GSW PTQPTIQ----CNLPAEVSVLCEKFRSYYLG-------THTGRRLSW-QTNMGTADIKAV FGKGQ------------------------------------------------------- ------------------------------------------------KHELNVSTFQMC VLMLFNNSDR-----------------------LSYKEIEQATEIP-----TPDLKRCLQ SMACVKGKN-VLRKEPMS------------------------------------------ --------KEIAEEDWFVVNDRFA----SKFYKVKIG----------------------- -TVVAQ-KETEPEKQ-ETRQRVEE-DRKPQIEAAIVRIMKSRRVLDHNNIIAEVTKQLQT ---RFLANPTEIKKRIESLIERDFLERDNTDRKLYRYLA >Vitis_vinifera_AM484063.2| . EFIS--LFVDDKLRKG------------------LKGVSEE---DVEIILDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAERSLIVKLK------ ----------TECGYQFTCKLEGMFT---DMKTSQDTMQGFNSAH--------------- ---------------------------------GADLGDGPTLAVTVLTT-------GSW PTQPSXT----CNLPTEMLALCEKFRSYYLG-------THTGRRLTW-QTNMGTADIKAT FAKGQ------------------------------------------------------- ------------------------------------------------KHELHVSTYQMC VLMLFNNADR-----------------------LSYKEIEQATEIP-----ASDLKRCMQ SMACVKGKN-VLRKEPMS------------------------------------------ --------KDIGEDDVFFVNDKFT----NKLYKVKIG----------------------- -TVVAQ-KETEPEKQ-ETRQRVEE-DRKPQIEAAIVRIMKSRRVLDHNNLIAEVTKQLQS ---RFLANPVEIKKRIESLIERDFLERDNVDRKLYRYLA >Vitis_vinifera_AC233371.1| . EFIS--LFVDEKLRKG------------------LKGVSEE---DVEVILDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAERSLIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSQDTMQGFHTAY--------------- ---------------------------------GAELGDGPSLVVQVLTT-------GSW PTQPGVT----CNLPAELSALCEKFRSYYLG-------THTGRRLSW-QTNMGTADLKAT FGKGQ------------------------------------------------------- ------------------------------------------------KHELNVSTYQMC VLMLFNNADR-----------------------LMYKEIEQATEIP-----SSDLKRCLQ SLACVKGKN-VLRKEPMS------------------------------------------ --------KDIGEDDAFFVNDKFT----SKFYKVKIG----------------------- -TVVAQ-KESEPEKQ-ETRQRVEE-DRKPQIEAAIVRIMKSRKVLDHNNIIAEVTKQLQP ---RFLANPGEIKKRIESLIERDFLERDNADRRLYRYLA >Populus_trichocarpa_NZ_AARH01004320.1| . EFIS--LFVDDKLRKG------------------LKGVSEE---DVEIILDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAERSLIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSQDTMQGFYASH--------------- ----------------------------------LELGDARTLVVQVLTT-------GSW PTQPGVT----CNLPAEMSALCEKFRSYYLG-------THTGRRLSW-QTNMGTADVKAT FGKGGQ------------------------------------------------------ ------------------------------------------------KHELNVSTYQMC VLMLFNNAER-----------------------LSYKEIEQATEIP-----AADLKRCLQ SMACVKGKN-VLRKEPMS------------------------------------------ --------KDIGEEDVFFVNDKFT----SKFYKVKIG----------------------- -TVVAQ-KESEPEKQ-ETRQRVEE-DRKPQIEAAIVRIMKSRRVLDHNNIITEVTKQLQS ---RFLANPTEIKKRIESLIERDFLERDSVDRKLYRYLA >Populus_trichocarpa_NZ_AARH01003597.1| . EFIS--LFVDDKLRKG------------------LKGVSEE---DVEIILDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAERSLIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSQDTMQGFYASH--------------- ----------------------------------PELGDGPTLVVQVLTT-------GSW PTQPGVP----CNLPAEMSALCEKFRSYYLG-------THTGRRLSW-QTNMGTADIKAT FGKGQ------------------------------------------------------- ------------------------------------------------KHELNVSTYQMC VLMLFNNADR-----------------------LGYKEIEQATEIP-----TADLKRCLQ SMACVKGKN-VLRKEPMS------------------------------------------ --------KDIGEEDAFFVNDKFT----SKFYKVKIG----------------------- -TVVAQ-KESEPEKQ-ETRQRVEE-DRKPQIEAAVVRIMKSRRVLDHNNIITEVTKQLQS ---RFLANPTEIKKRIESLIERDFLERDSVDRKLYRYLA >Ricinus_communis_AASG02000361.1| . EFIS--LFVDDKLRKG------------------LKGVSEE---DVEIILDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAERSLIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSQDTIQGFYASH--------------- ----------------------------------PELGDGPTLVVQVLTT-------GSW PTQPSVT----CNLPAEMSALCEKFRSYYLG-------THTGRRLSW-QTNMGTADIKAT FGRGQ------------------------------------------------------- ------------------------------------------------KHELNVSTYQMC VLMLFNNADR-----------------------LSYKEIEQATEIP-----ASDLKRCLQ SMACVKGKN-VLRKEPMS------------------------------------------ --------KDIGEEDAFFVNDKFT----SKFYKVKIG----------------------- -TVVAQ-KESEPEKQ-ETRQRVEE-DRKPQIEAAIVRIMKSRRVLDHNNIITEVTKQLQS ---RFLANPTEIKKRIESLIERDFLERDSVDRKLYRYLA >Medicago_truncatula3_FP017207.1| . EFLS--SFLDVKLRKG------------------FEGNSE----EI--ILDKVMMFIKLL -HDKDLFHKYYKKHLPKRLLFGKT----------------ISEDIERSLAVKLK------ ----------RVCGYKF-ALLEIMVM---DIKTSKEMLQGFYRSH--------------- ----------------------------------AKLGDDPKLIFQVLTT-------GSW PLLRTTD--SSCNLPVEVSALHEKYKSYYLG-------INAGKKLSL-QPNMGNAEIIAT FGNGR------------------------------------------------------- ------------------------------------------------KHELHVSTYQMC VLMLFNDIDQ-----------------------LSYKDIETATKIN-----SLDLIKCLY SMVFVNGKN-IIKKVPMN------------------------------------------ --------GNISEGDVFFINDMFK----SKFYKIKLE----------------------- -TVATQ-RESEHEKL-QTRKNVEE-DRRPKIEAAIVRIMKFKKQLDHKNIIAEVTKELKS ---LFLLNPTEIKKRIESLIERDYLERDNIHNNLNRYLA >Chlamydomonas_reinhardtii_XM_001700825.1| . EFIS--LFIDDKLRRG------------------IKGLSDT---DVEGVLDKVMALFRYL -QEKDVFEKYYKQHLAKRLLSGRT----------------TSDDAERNLLVKLK------ ----------TECGYQFTSKLESMFT---DIKTSRDTMNEFRTRL--------------- ----------------------------VETGKLEAELGGIDLQVQVLTT-------GSW PTQAPSK----CNLPRELEAACESFRNFYLS-------THSGRRLTF-QPNMGTADLRAV FGAGR------------------------------------------------------- ------------------------------------------------RHELNVSTYQMC VLLLFNEADS-----------------------LSYRDIAQATEIP-----APDLKRALQ SLACVKGRN-VLRKEPAG------------------------------------------ --------KDVADSDVFFYNDKFT----SKLIKVKIS----------------------- -TVAAT-KEGESEKA-ETRQKVEE-DRKPQIEAAIVRIMKARQRLDHNTIITEVTRQLQA ---RFVPNPATIKKRIESLIEREFLARDEADRKFYTYVA >Medicago_truncatula2_FP017207.1| . EYIS--LFVDDKLRKG------------------LNGVSED---DLEVTLEKVMMLFRYL -QEKDVFEKYYTQHLAKRLLAGKT----------------VSEDAERSLIIKLK------ ----------KECGYQFTSKLEGMLK---DMKASLDTTKGFYANH--------------- ----------------------------------PELGDGPILTMQVLTT-------GFW PTQSSVT----CNLPAEMSALCVKFQSYYLG-------NQNGRRLSW-QTEMGTADLKAT FGNGQ------------------------------------------------------- ------------------------------------------------KHELNVSTYQMC VLMLFNNADR-----------------------LSYREIEQATEIP-----ASDLKRCLQ SLALVKGRN-VLRKEPMS------------------------------------------ --------KDVSEDDAFIVNDKFS----SKLYKVKIG----------------------- -TVVTQ-KESEPEKL-KIRQRVVE-DQKPQIEAAIVRIMKSRKQLEHNNLIAEVTKQLQS ---RFLANPTDIKKRIESLIERDFLERDDSDRKLYLYLA >Medicago_truncatula_FP017207.1| . EYIS--LFVDDKLRKG------------------LKGVSED---VVEITLDKVMVLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------VSDDAERSLIVKLK------ ----------TECGFQFTAKLEGMFT---DMKTSVDTMKSFNANH--------------- ----------------------------------PELGDGPTLTVQVLTT-------GSW PAQSSVT----CNLPTEMSALCEKFRSYYLS-------THNGRKLTW-QTNMGTADLKAT FGSGQ------------------------------------------------------- ------------------------------------------------KHELNVSTYQMC ILMLFNNADR-----------------------LSYREIEQATEIP-----ASDLKRCLQ SLALVKGRN-VLRKEPMG------------------------------------------ --------KDVSEDDTFYVNDRFS----SKLYKIKIG----------------------- -TVVAQ-KESELEKL-DTRQKAEE-DRKPQIEAAIVRIMKSRKQLEHNNLMAEVTQQLQS ---RFLTNPTDVKKRIESLLEREFLERDAVDRKLYRYLA >Zea_mays_AC215673.3| . EFIS--LFVDDKLRKV------------------VKEANEE---DLETVLDKVMTLFRYL -QEKDLFEKYYKQHLAKRLLCGKA----------------APEDSERSMLVKLK------ ----------TECGYQFTSKLEGMIT---DLNTSQDTTQGFYAST--------------- --------------------------------SSRLLADAPTISVQILTT-------GSW PTQTCNT----CNLPPEIVSVSEKFRAYYLG-------THNGRRLTW-QTNMGNADIKAT FGNGN------------------------------------------------------- ------------------------------------------------KHELNVSTYQMC VLMLFNSSNV-----------------------LTYREIEQSTAIP-----TADLKRCLL SLALVKGRQ-VLRKEPMS------------------------------------------ --------KDIADDDSFCVNDKFT----SKLFKVKIN----------------------- -PVVTQ-KETDPEKL-ETRQRVEE-DRKPQIEAAIVRIMKSRRVLDHNSIMTEVTKQLQP ---RFMPNPVVIKKRIESLIEREFLERDKVDRKMYRYLA >Oryza_sativa_Japonica_AK066234.1| . EFIS--LYVDDKLRKG------------------MKEANEE---DVETVLDKVMMLFRYL -QEKDLFEKYYKQHLAKRLLSGKA----------------ASDDSERSMLAKLK------ ----------TECGYQFTSKLEGMFN---DLKTSHDTTQRFYAGT--------------- ----------------------------------PDLGDAPTISVQILTT-------GSW PTQPCNT----CNLPPEILGVSEMFRGFYLG-------THNGRRLTW-QTNMGTADIKAV FGNGS------------------------------------------------------- ------------------------------------------------KHELNVSTYQMC VLMLFNSADC-----------------------LSYRDIEQTTAIP-----SADLKRCLQ SLALVKGKN-VLRKEPMS------------------------------------------ --------RDISDDDNFYVNDKFT----SKLFKVKIG----------------------- -TVATQ-KESEPEKM-ETRQRVEE-DRKPQIEAAIVRIMKSRRVLDHNSIVTEVTKQLQP ---RFMPNPVVIKKRVESLIEREFLERDKTDRKLYRYLA >Oryza_sativa_XM_474079.1| . EFIS--LFVDDKLRKG------------------VKGANEE---DVETVLDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSGKT----------------TSDEAERSMLVKLK------ ----------TECGYQFTSKLEGMFN---DLKTSHDTMQSFYANL--------------- ----------------------------------SGDTDSPTISVQILTT-------GSW PTQPCTP----CKLPPEIVDISEKFRAFYLG-------THNGRRLTW-QTNMGNADIKAT FG-GR------------------------------------------------------- ------------------------------------------------RHELNVSTYQMC VLMLFNSADG-----------------------LTYGDIEQATGIP-----HADLKRCLQ SLACVKGKN-VLRKEPMS------------------------------------------ --------KDISEDDTFYYNDKFT----SKLVKVKIG----------------------- -TVVAQ-KETEPEKL-ETRQRVEE-DRKPQIEAAIVRIMKSRRVLDHNSIITEVTKQLQS ---RFLPNPVVIKKRIESLIEREFLERDKVDRKMYRYLA >Thalassiosira_pseudonana_AAFD02000036.1| . --LA--VYVDELLRVG------------------LRGADER---KVSSELDRAIVIFRFL -ADKDVFEAYYKSHLAKRLLGNKS----------------GNEDAERAMVSLLK------ ----------AECGYQFTSKLEGMFN---DIRISKETAEKYRSHK--------------- --------------------KKSNNEVSNDSRDAENGDKPVDVEVSVLTT-------GYW PSQNVPP----CILPPPVRAAMDRFQKYYLN-------TYTGRKLSW-QTLAGTAEIRAT FPPPKGSSK--------------------------------------------------- ----------------------------------------------PRRHDLTVTTYQMC ILVLFNNRDT-----------------------LTLKQIREEIQIP-----EDELRRHLV SLCTPKHR--ILKKGSKGK----------------------------------------- --------AISGDDDTFTYNSDYT----SKMTKVKVPMVSMRDATASAKSDGAAGSSSAA AASSSTNTGLVDGSS-TVPASVEE-DRRHLLEAAIVRIMKARKMLNHNDLVAEVTKQLAG ---RFIPPPQFVKKRVESLIEREYLERDEADRRVYLYMA >Phaeodactylum_tricornutum_XM_002182866.1| . --LA--TYVDELLRVG------------------LRGATEV---QILDSLNQAIVIFRFL -SDKDVFESFYKQQLAKRLLGGRS----------------VSDDAERSMVSLLK------ ----------AECGYQFTTKLEGMFN---DMRISRETRDKYKSFK--------------- --------------------------------RQEGEKNMVDIEVDVLTT-------GYW PSQNVPP----CTLPVPIQESIDRFSKFYLD-------KHTGRKLKW-QTNTGAAELKVT FGTGPDK----------------------------------------------------- ----------------------------------------------YRRHELCVSTYQMC ILLLFNDKET-----------------------LTLAQIRQQTQIP-----DQELRRHLI SLCTPKNR--ILKKGSKGR----------------------------------------- --------GIISDEDTFTYNMDFT----SKLKRVRIPLVKEASMVRPETAAG-------- -LIGADGKDAHVAPG-SVPVSVEE-DRRHLVEAAIVRIMKARKALNHNDLIAEVTRQLTN ---RFQPTPQFIKKRIESLIDREYLERSEREHRVYNYVA >Tetrahymena_thermophila_XM_001026152.1| . ELTS--KHIDTKLKKN-------------------KTMQDH---DIEKDVDDALELFRYL -PAKDIFEAFYNKRLARRLLMNLA----------------YSYELERKVLDRLR------ ----------SECGD-YTMKADEILK---DVNESK-LNKDFNDYL--------------- -------------------------------SSGLDYNKKNIFSCIVVSS-------SAW PMKN-------LPILFEPFDKFKEFKKFYEL-------KHKGVCINW--HETSTCDIGNY NKEK-------------------------------------------------------- ----------------------------------------------------YIFVLIGL ILLCFNLKNK-----------------------LSYTEIHNLVIDE------EELKKNLV SLYAMKDTK-LLNKSGEA------------------------------------------ --------KRVDETDVFEVNEAYS-----KKKLIKVN----------------------- ---SIFKKETKEDVK-ETTDRVLT-ERGFVLDASIVKILKSKKNI-YHELMKELFNDL-- ---MLPINASEVKKRIEGLIDREYMKRDPENHSLYHYVA >Hyaloperonospora_parasitica_ABWE01000950.1| . -YLA--HYLDELLRSK-------------------NRFEE----EMDTRVSHVIALFRYL -QDKDVFEEFYKVLLAKRLLNSRG----------------TSDEAEKLVISKLK------ ----------AECGYQFTSKLEGMFK---DMSISKDLMELYRKSG--------------- ------------------------YETRCSGVGVNTSIAPVPLSVHVLTS-------GFW PTEMVPS----CALPPELVQLTEVFESFYNA-------RHNGRKLAW-MTNMGTVDIRAT FSAGVEDP---------------------------------------------------- ----------------------------------------------KRRHELNVSTYQAV ILMLFNQRSQ-----------------------WRFKELVERTRID-----AKDLKRHLI SLCTPKYK--ILIKSSKGK----------------------------------------- --------RIDEEIDVFTVNGAYK----SKLHRVRIPLVSQK-----------------E TSLLPAMALSSSNRE-ALPPTVAE-DRKHLVEAAIVRIMKTRKQMPHNQLIAEVTRQMTS ---RFTPSPQLIKLRIESLIEREYLQRSTTDRRMYNYLA >Phytophthora_capsici_BT032078.1| . -YLA--HYLDELLRSK-------------------NRFEE----EMDTRVTQVIALFRYL -QDKDVFEEFYKVLLAKRLLNSRG----------------TSDEAEKLVISKLK------ ----------AECGYQFTSKLEGMFK---DMSISKDLMELYRKSG--------------- ------------------------------DSGLDLSVASTPLSVHVLTS-------GFW PTEMAPM----CALPQDLVEMTQAFEVFYYA-------RHNGRKLAW-MVNMGTVDVRAS FSAGVEDS---------------------------------------------------- ----------------------------------------------KRRHELNVSTYQSV ILMLFNQRSE-----------------------WSFKDIVERTRID-----VKDLKRHLI SLCTPKYR--ILIKSSKGK----------------------------------------- --------RIDEEADTFTVNDSYK----SKLHRVRIPLVSQKE----------------T SLLPAVASSSSNSAD-VLPPTVAE-DRKHLVEAAIVRIMKTRKQMQHNQLIAEVTRQMAG ---RFTPSPQLIKLRIESLIEREYLQRSATDRRMYNYLA >Phytophthora_infestans_AATU01001477.1| . -YLA--HYLDELLRSK-------------------KRFEE----EMDTRVTQVIALFRYL -QDKDVFEEFYKVLLAKRLLNSRG----------------TSDEAEKLVISKLK------ ----------AECGYQFTSKLEGMFK---DMSISKDLMELYRKSG--------------- ------------------------HDTRGTGFGIDMSVAPMPLSVHVLTS-------GFW PTEMAPM----CALPLELVQMTQAFESFYYA-------RHNGRKLAW-MANMGTVDVRAM FSAGLEDA---------------------------------------------------- ----------------------------------------------KRRHELNVSTYQAV ILMLFNQRSE-----------------------WRFKELLERTRID-----VKDLKRHLI SLCTPKYK--ILIKSSKGK----------------------------------------- --------RIDEETDTFSVNDSYK----SKLLRVRIPLVSQKE----------------T SLLPAVASSTNNAAD-ALPPTVAE-DRKHLVEASIVRIMKTRKQMQHNQLIAEVTRQMTG ---RFTPSPQLIKLRIESLIEREYLQRSITDRRMYNYLA >Phytophthora_ramorum_AAQX01000428.1| . -YLA--HYLDELLRSK-------------------NRFEE----EMDTRVTQVIALFRYL -QDKDVFEEFYKVLLAKRLLNSRG----------------TSDEAEKIVISKLK------ ----------AECGYQFTSKLEGMFK---DMSISKDLMELYRKSG--------------- ------------------------YETRGSGFGIDISVAPMPLSVHVLTS-------GFW PTEMAPM----CALPLELVQLTQTFEGFYYA-------RHNGRKLAW-MANMGTVDMRAT FSAGVEDG---------------------------------------------------- ----------------------------------------------KRRHELNVSTYQAV ILMLFNQSPE-----------------------WRFKELVERTRID-----VKDLKRHLI SLCTPKYK--ILIKSSKGK----------------------------------------- --------RIDEEADSFIVNDAYK----SKLHRVRIPLVSQKE----------------T SLLPAVASSSGNPAD-ALPPTVAE-DRKHLVEAAIVRIMKTRKQMQHNQLIAEVTRQMAG ---RFTPSPQLIKLRIESLIEREYLQRSTTDRRMYNYLA >Phytophthora_sojae_AAQY01000490.1| . -YLA--HYLDELLRSK-------------------NRFEE----EMDTRVTQVIALFRYL -QDKDVFEEFYKVLLAKRLLNSRG----------------TSDEAEKLVISKLK------ ----------AECGYQFTSKLEGMFK---DMSISKDLMELYRKSG--------------- ------------------------YDTRGSGFSIDPSVAPMPLSVHVLTS-------GFW PTEMSPM----CALPLELVQLTQTFESFYYA-------RHNGRKLAW-MANMGTVDVRAT FSAGVEDG---------------------------------------------------- ----------------------------------------------KRRHELNVSTYQAV ILMLFNQRVE-----------------------WRFKDLVDRTRID-----VKDLKRHLI SLCTPKYK--ILIKSSKGK----------------------------------------- --------RIDEEVDVFTINDAYK----SKLHRVRIPLVSQKE----------------T SLLPVVASSSSNPAD-ALPPTVAE-DRKHLVEAAIVRIMKTRKQMQHNQLIAEVTRQMAG ---RFTPSPQLIKLRIESLIEREYLQRSTTDRRMYNYL- >Phaeodactylum_tricornutum_XM_002182601.1| . ELMS--TFCDRILKSG------------------GEKLSEA---EVEESLDRIVQLFSYL -TDKDLFAEIYRNQLSKRLLNQRS----------------TSDDAEKLMIAKLK------ ----------VQCGTQFTSKMEGMLA---DLAVGSQQRTEFEQRM--------------- ----------------------------------RQVETSLDFSVQVLTT-------GFW PTYKSPQ----VTLTEEMNKCMKVFREWHEL-------KHQKRKLGW-VLTQGSATVRGT FGKK-------------------------------------------------------- ------------------------------------------------SYEIQVSTLQAI ALDALSGGET-----------------------LSFEDLSQRLNLE-----ETILKPLMH SLSCGKYK--VIAKTPAS------------------------------------------ --------NKINTTDKFTANAKFS----SNMRKIRIP----------------------- --------MASLDAN-FNTKKVEE-DRSIAIEAAIVRIMKARKTLQHQQLLSEVLAQLS- ---FFNPNPRVVKKRIEALIDREYLERGTDNPGVYNYLA >Zea_mays_AC201762.3| . EFIS--LYVDDKLRKG------------------LKGATEE---DVEVILDKVMMLFRYL -QEKDVFEKYYKQHLAKRLLSSKT----------------VSDDAERSMIVKLK------ ----------TECGYQFTSKLEGMFT---DMKTSQDTMQDFYAKK--------------- ---------------------------------SEELGDGPTLDVHILTT-------GSW PTQPSPP----CNLPTEILTVCEKFRAYYLG-------THNGRRLTW-QTNMGTADIKAT FGKGQ------------------------------------------------------- ------------------------------------------------KHELNVSTYQMC VLMLFNNADG-----------------------LTYKDIERDTEIP-----ASDLKRCLQ SLACVKGKN-VLRKEPMS------------------------------------------ --------KDISEDDTFYFNDKFT----SKLVKVKIG----------------------- -TVVAQ-KESEPEKQ-ETRQRVEE-DRKPQIEAAIVRIMKSRRVLDHNSIVAEVTKQLQA ---RFLPNPVVIKKRIESLIEREFLERDKVDRKLYRYLA >Arabidopsis_thaliana_AY133878.1_Cul1_AT4g02570 . ELLA--TFCDNILKKG-----------------GSEKLSDE---AIEDTLEKVVKLLAYI -SDKDLFAEFYRKKLARRLLFDRS----------------ANDDHERSILTKLK------ ----------QQCGGQFTSKMEGMVT---DLTLARENQNSFEDYL--------------- -------------------------------GSNPAANPGIDLTVTVLTT-------GFW PSYKSFD----INLPSEMIKCVEVFKGFYET-------KTKHRKLTW-IYSLGTCHINGK FDQK-------------------------------------------------------- ------------------------------------------------AIELIVSTYQAA VLLLFNTTDK-----------------------LSYTEILAQLNLS-----HEDLVRLLH SLSCAKYK--ILLKEPNT------------------------------------------ --------KTVSQNDAFEFNSKFT----DRMRRIKIP----------------------- -------LPPVDERK-KVVEDVDK-DRRYAIDAAIVRIMKSRKVLGHQQLVSECVEQLSR ---MFKPDIKAIKKRMEDLITRDYLERDKENPNMFRYLA