A. Ras-related GTP-binding protein (Rrag)

>OUTGROUP_C._intestinalis_Rragc/dlike(ENSCING00000005166)
SSDMKPRILIMGLQRSGKSSIQKVVFHKMSPNETLFLESTSKIFKDDVSNNSFINFQIWD
IPGQIDFLDNTFDLDMIFGGTGALIFVVDAQDDYMEALTCLHQTVSKAFRVNPQIKFEIF
IHKVDGLSDDHKIETQRDISQRANEELHEAGLRDLHLSFHLTSIYDHSIFEAFSKVVQKL
IPQLTTLENLLSIFVQNSGVEKTFLFDVVSKIYIATDGSPVDMQSYELCCEMIDVMLDMT
CIYG-DETDDGTPQD--STCIIRLNNTSILYLQEVTRFLVLVCILRDDSFTRRGIIDYNI
LLLKKAINDVFDVRLRQGK-----

>Chicken_Rragc_Chr23(ENSGALG00000001487)
GADSKPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWD
FPGQMDFFDPTFDYEMIFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVNPEMNFEVF
IHKVDGLSDDHKIETQRDIHQRANDDLTDAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKL
IPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVS
CIYGLKEDGTGSAYDKESMAIIKLNNTTVLYLKEVTKFLALVCILREESFERKGLIDYNF
HCFRKAIHEVFEVGVASHRNGTPR

>Stickleback_Rragc_2_GroupX(ENSGACG00000002629)
APADKPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISSTSFVNFQIWD
FPGQVDFFDPSFDSEMIFSGAGALIFVIDAQDDYVEALGRLHLTISRAYKVNPDINFEVF
IHKVDGLSDDHKIETQRDIHRRANDDLADASLEKLHLSFYLTSIYDHSIFEAFSKVVQKL
IPQLPTLENLLNIFISHSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVS
CIYGLMEDGSGCAYDSGSMAIIRLNNTTVLYLKEVTKFLALVCILREEGFERKGLIEYNF
HCFRKAIHEVFEVGAPPQDGV---

>Zebrafish_Rragc(1)_Chr16(ENSDARG00000069829)
PSDSKPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISSSSFVNFQIWD
FPGQVDFFDPTFDYEMIFRGTGALIFVIDAQDDYVEALSRLHLTVSRAYRVNPEINFEVF
IHKVDGLSDDHKIETQRDIHQRANDDLADASLEKLHLSFYLTSIYDHSIFEAFSKVVQKL
IPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVS
CIYGLKEDGSGSAYDKESMAIIKLNNTTVLYLKEVTKFLALVCILREESFERKGLIDYNF
HCFRKAIHEVFEVGVSTSRNGTPR

>Mouse_Ragc_Chr4(ENSMUSG00000028646)
ADSSKPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWD
FPGQMDFFDPTFDYEMIFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVNPDMNFEVF
IHKVDGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKL
IPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVS
CIYGLKEDGSGSAYDKESMAIIKLNNTTVLYLKEVTKFLALVCILREESFERKGLIDYNF
HCFRKAIHEVFEVGVTSHRNGTPR

>Human_Rragc_Chr1(ENSG00000116954)
ADSSKPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWD
FPGQMDFFDPTFDYEMIFRGTGALIYVIDAQDDYMEALTRLHITVSKAYKVNPDMNFEVF
IHKVDGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKL
IPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVS
CIYGLKEDGSGSAYDKESMAIIKLNNTTVLYLKEVTKFLALVCILREESFERKGLIDYNF
HCFRKAIHEVFEVGVTSHRNGTPR

>Frog_Rragc_Scaffold403(ENSXETG00000005266)
SSDSKPRILLMGMRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISNSSFVNFQIWD
FPGQVDFFDPTFDYEMIFRGTGALIYVIDAQDDYMEALARLHATVSKAYKANPDMNFEVF
IHKVDGLSDDHKIETQRDIHQRANDDLADAGLEKLHLSFYLTSIYDHSIFEAFSKVVQKL
IPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVS
CIYSLHADCNGSAYDKESMAIIKLNNTTVLYLKEVTKFLSLVCILREESFERKGLIDYNF
HCFRKAIHEVFEVGAASHRNGTPA

>Mouse_Rragd_Chr4_(ENSMUSG00000028278)
STEVKPRILLMGLRRSGKSSIQKVVFHKMSPSETLFLESTNRICREDVSNSSFVNFQIWD
FPGQIDFFDPTFDYEMIFRGTGALIFVIDSQDDYMEALARLHLTVTRAYKVNTDINFEVF
IHKVDGLSDDHKIETQRDIHQRANDDLADAGLEKIHLSFYLTSIYDHSIFEAFSKVVQKL
IPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSTPVDMQTYELCCDMIDVVIDIS
CIYGLKEDGAGAPYDKDSTAIIKLNNTTVLYLKEVTKFLALVCFVREESFERKGLIDYNF
HCFRKAIHEVFEVRMKMVKNGTPR

>Chicken_Ragd_Chr3(ENSGALG00000015771)
STEVKPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKICREDVSNSSFVNFQIWD
FPGQIDFFDPTFDYEMIFRGTGALIFVIDSQDDYMEALARLHLTVTRAYKVNPDINFEIF
IHKVDGLSDDHKIETQRDIHQRANDDLADAGLEKIHLSFYLTSIYDHSIFEAFSKVVQKL
IPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSTPVDMQTYELCCDMIDVVIDIS
CIYGLKDDGTGTPYDKESMAIIKLNNTTVLYLKEVTKFLALVCFVREESFERKGLIDYNF
HCFRKAIQEVFEVRMKVVRNGTPR

>Human_Rragd_Chr6(ENSG00000025039)
STEVKPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKICREDVSNSSFVNFQIWD
FPGQIDFFDPTFDYEMIFRGTGALIFVIDSQDDYMEALARLHLTVTRAYKVNTDINFEVF
IHKVDGLSDDHKIETQRDIHQRANDDLADAGLEKIHLSFYLTSIYDHSIFEAFSKVVQKL
IPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSTPVDMQTYELCCDMIDVVIDIS
CIYGLKEDGAGTPYDKESTAIIKLNNTTVLYLKEVTKFLALVCFVREESFERKGLIDYNF
HCFRKAIHEVFEVRMKVVKNGTPR

>Frog_Rragd_Scaffold599(ENSXETG00000019115)
STEVKPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKICREDVSNSSFVNFQIWD
FPGQIDFFDPTFDYEMIFRGTGALIFVIDSQDDYMEALARLHLTVTSAYKVNPDINFEVF
IHKVDGLSDDHKIETQRDIHQRANDDLVDAGLEKIHLSFYLTSIYDHSIFEAFSKVVQKL
IPQLPTLENLLNIFISNSGIEKVFLFDVVSKIYIATDSSPVDMQTYELCCDMIDVVIDIS
CIYGL--EGAGTPYDKESLAIIKLNNTTVLYLKEVTKFLALVCFVREESFERKGLIDYNF
HCFRKAIQEVFEVRVKVLRNGTPG

>Zebrafish_Rragd_Chr17(ENSDARG00000006279) 
SSEVKPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKICREDVSNSSFVSFQIWD
FPGQIDFFDPTFDYEMIFRGTGALIFVIDTHDDYVEALSRLHLTVTRAYKVNPDINFEVF
IHKVDGLSDDHKIEKQRDIHKRANDDLADAGLERIHLSFYLTSIYDHSIFEAFSKVVQKL
IPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQTYELCCDMIDVVIDIS
CIYGLSGDEGGTPYDKESMAIIHLNNTTVMYLKEVTKFLALVCFLREESFEKKGLIDYNF
HCFKKAIEEVFDVRLKVQR-----

>Zebrafish_Rragc(2)_Chr19(ENSDARG00000059154)
SADNKPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKIYKDDISGSSFVNFHIWD
FPGQVDFFDPTFDYEMIFRGTGALIFVIDAQDDYVEALGRLHLTVSRAFRVNPEINFEVF
IHKVDGLSDDHKIETQRDIHQRANDDLADASLEKLHLSFYLTSIYDHSIFEAFSKVVQKL
IPQLPTLENLLNIFISNSGIEKAFLFDVVSKIYIATDSSPVDMQSYELCCDMIDVVIDVS
CIYGLKDEGNGNAYDKESLAIIKLNNTTVLYLKEVTKFLALVCILREESFERKGLIDYNF
HCFRKAIHEVFEVSGSTQRNGTPR

>Stickleback_Rragd_GroupXV(ENSGACG00000013038) 
NGEVKPRILLMGMRRSGKSSIQKVVFHKMSPNETLFLESTNKICREDVSSSSFVSFQIWD
FPGQIDFFDPTFDYEMIFRGTGALIFVIDSQDDYVEALSRLHLTVTRAYKVNPEINFEVF
IHKVDGLSDDNKIEKQRDIQKRASDDLADAALEHIHLSFYLTSIYDHSIFEAFSKVVQKL
IPQLPTLENLLNIFISNSGIEKAFLFDVVSKINIATDSSPVDMQTYELCCDMIDVVIDIS
CIYGLTDSEAGLPYDEESMAIIHLNNTTVMYLKEVTKFLAIVCFVRKESFERKGLIDYNF
HCFKKAIQEVFDVRVEVQQNGGPS


B. Heterogeneous nuclear ribonucleoprotein (Hnrnp) family

>Chicken Hnrnpr_Chr23(ENSGALG00000000814)
MANQVNGNEEPMDTSS-VTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDERAID
ALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGKVQESTKGPDEAKI
KALLERTGYTLDVTTGQRKYGGPPPDTVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEK
AGPIWDLRLMMDPLSGQNRGYAFITFCSKDAAQEAVKLCDNYEIRPGKHLGVCISVANNR
LFVGSIPKNKTKENILEEFNKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARR
RLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKL
ERVKKLKDYAFVHFEDRGAAVKAMNEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASR
STAYEDYYYYPPPRMPPPIRGRGRGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYED
PYYGYDDGYAIRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPGNVGGRQTNNQQNWGSQPI
AQQPQGGDYAGNYGYNNDNQEFYQDTYGQQW

>OUTGROUP_ Ciona_intestinalis_Hnrnpr_ Chr12qENSCING00000000345
---MEEIKQ----VPG-ENSTEYLQELNAAGLSVNVAQGLHEVFKQDLVKFSDLDERAIE
ALKELDEEGALAVLKQFNESNLQHVHNKSAFLCGVIKIHRQRCKEENGDTKKSGPNEDKI
QELLERTKYSLDVTTGQRRYGGPPPKDVYDGAEPGTGCQVFVGRIPRFVFEDELVPLLEE
AGVVWDFRLMMDPMSGQNRGYGFVTYTNKEAATECVKMLDNYEIRPKKFLGVCVSQSNCR
LFVGSIPKTKTKDEIFEEFDGITQGLKDVIIYLQTEDKMKNRGFCFLEYTDHKAASQARR
RLSSVKVKAFNNTVSVDWADPVEEPSDEIMSKVKVLYIKNLSMKATEEIVMATFSAYGEV
ERVKKIKDYAFVHFKERDNAMKALEELNGLNLEGEAIEISLAKPVDKKKKERQMERKMMT
HAYGMGYGNRAGYNMRGRGRGMYGGQIPPMGFGFNDDYFTTDYMGYGY---------YDD
PFFGMPMRGGYRNGM-------YGGFN--RGRGTGVRGRGR-------------------
-------------------------------

>Frog_Hnrnpr_ Scaf411(ENSXETG00000007102)
------------------------------------------------------------
-------------------------------SELVMKNYRQREKQGKAQESAKAPDEAKI
KALLERTGYTLDVTTGQRKYGGPPPESVSSGAQPGIGTEVFVGKIPRDLFEDELVPLFEK
AGPIWDLRLMMDPLSGQNRGYAFITFCNKEAAQEAVKLCDNYEIRPGKHIGVCISVANNR
LFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARR
RLMSGKVKVWGNVVTVEWADPVEEPDPEIMAKVKVLFVRNLSSTVTEEILEKAFSVFGKL
ERVKKLKDYAFVHFDERDAAVRAMDEMNGTELEGEEIEIVLAKPPDKKRKERQAARQASR
GSSYDDYYYYPPPRMPPPGRGRGRGGRGGYSFPQDYYGYEDYYDDYYAYDYHDYRGGYDD
PYYGYDDGYPVRGRGGPPPPRGRSVPPQRGGRSSYAPRGSPGNVGGRQTNNQQNWGTQPI
AQQPQGGDYTGNYGYSNDNQEFYQDTYGQQW

>Mouse_Hnrpnr_Chr4(ENSMUSG00000066037)
MANQVNGNEEPMDTSS-VTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDERAID
ALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGKVQESTKGPDEAKI
KALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEK
AGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANNR
LFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARR
RLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKL
ERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASR
STAYEDYYYHPPPRMPPPMRGRGRGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYED
PYYGYDDGYAVRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPGNVGGRQTNNQQNWGSQPI
AQQPQGGDYSGNYGYNNDNQEFYQDTYGQQW

>Human_Hnrnpr_Chr1(ENSG00000125944)
MANQVNGNEEPMDTSS-VTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDLDERAID
ALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGKVQESTKGPDEAKI
KALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEK
AGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANNR
LFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARR
RLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEFGKL
ERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASR
STAYEDYYYHPPPRMPPPIRGRRGGGRGGYGYPPDYYGYEDYYDDYYGYDYHDYRGGYED
PYYGYDDGYAVRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPGNVGGRQTNNQQNWGSQPI
AQQPQGGDYSGNYGYNNDNQEFYQDTYGQQW

>Zebrafish Hnrnpr_Scaffold Zv7_NA3159(ENSDARG00000014569)
MAAEVNGSEEPMEVTA--PRSENYQALLDAGLPQKVAESLDNIFQTGLVAYADLDERALD
ALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGKVQESSKGPDETKI
KALLDRTGYTLDVTTGQRKYGGPPPDAVFSGPQPGIGTEVFVGKIPRDLYEDELVPLFEK
AGSIWDLRLMMDPLTGQNRGYAFITFCSKDAAQEAVKLCDNYEIRSGKYLGVCISVANNR
LFVGSIPKNKTRESILEDFGKVTEGLQEVILYTQPDDKKKNRGFCFLEYEDHKSAAQARR
RLMSGKVKVWGNPVTVEWADPVAEPDPEIMAKVKVLFVRKLATPVTEELLEKTFSQFGKL
ERVKKLKDYAFVHFEERDAAVKAMQEMNGKELGGEEIEIVLAKPPDKKRKERQAARQTTR
NTGYDDYYYYPPPRMPPPGRGRGRGGRGGYSYPPDYYGYEEYYDDYYGGYDYHDYRGGYD
DPYYGYDDGYTMRSRGAPPPPRGRAAPPTRGRGGYPPRGGAGGNVGRRQTNQQNWGSQPI
AQQPQGGEYSSGYSYSNDSLEFSQDSYGQQW

>Stickleback_Hnrnpr_GroupX(ENSGACG00000003202)
AAAEVNGSEEPMDVTA--THTENYQTLVDAGLPQKVAESLDNIFQTGLVEYVDLDERAID
ALREFNEEGALTVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGKVQESTKGPDETKI
KALLERTGYTLDVTTGQRKYGGPPPEDVFKGIQPGIGTEVFVGKIPRDLYEDELVPLFES
AGPIWDLRLMMDPLSGQNRGYAFITYCNKDDAQKAVKLCDNHEIRPGKYLGVCISVANNR
LFVGSIPKNKTRESILEDFGKVTEGLQEVILYHQPDDKKKNRGFCFLEYEDHKSAAQARR
RLMSGKVKVWGNPVTVEWADPVAEPDPEVMAKVKVLFVRKLATAVTEELLEKTFSQFGKL
ERVKKLKDYAFVHFEERDSAVKAMDEMNGKELGGEDIEIVLAKPPDKKRKERQAARQTTR
NSGYDDYYYYQPPRMPPPGRGRGRGGRGGYAYPSDYYGYDDYYDDYYGYDYHDYRGGYED
PYYGYEDVYSMRGSRGGPPPPRARGAPPARGRGGYAQRGPPGNVGGRQTNNQQNWGSQPI
AQQPQGADYSGNYGYSNDTMEFSQDSYGQQW

>Frog_Syncrip_ Scaffold76(ENSXETG00000018075)
AAEHVNGNEEPMDTYAAVAQSEHMQTLLDAGLPQKVAEKLDEIYISGLVTHSDLDERAIE
ALKEFNEEGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGKVADSSKGPDESKI
KALLERTGYTLDVTTGQRKYGGPPPDFVHTGQQPSVGTEIFVGKIPRDLFEDELVPLFEK
AGSIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRPGKHIGVCISVANNR
LFVGSIPKSKTKEQIVEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARR
RLMSGKVKVWGNVVTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFGQFGKL
ERVKKLKDYAFIHFDERVGAVKAMEEMNGKELEGENIEIVFAKPPDQKRKERKAQRQAAK
NQMYDEYYYYGGPHMPPPSRGRGRGGRGGYGYPSDYYGYDDYYDYYGYDYHNYRGGYDDP
FYGYEDFQVGARGGARGAAPSRGRGAVPPRGRAGYSQRG--GGNVGRRQTNNQNWGSQPI
AQQPQGGDHSGNYGYKSENQEFYQDSFGQQ-

>Mouse_Syncrip_Chr9 (ENSMUSG00000032423)
ATEHVNGNEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIE
ALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGKVADSSKGPDEAKI
KALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEK
AGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNR
LFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARR
RLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKSFSQFGKL
ERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAK
NQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDP
YYGYEDFQVGARGGARGAAPSRGRGAAPPRGRAGYSQRGGPARGGAGPDLLQ--------
-------------------------------

>Chicken_Syncrip_Chr3 (ENSGALG00000015830)
ATEHVNGNEEPMDTSAAVTHSEHFQTLLDAGLPHKVAEKLDEIYVAGLVAHSDLDERAIE
ALKEFNEEGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGKVADSSKGPDEAKI
KALLERTGYTLDVTTGQRKYGGPPPESVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEK
AGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNR
LFVGSIPKSKTKEQIVEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARR
RLMSGKVKVWGNVVTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKL
ERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAK
NQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDP
YYGYEDFQVGARGGARGAAPSRGRGAAPPRGRAGYAQRG--GGNVGRRQTNNQNWGSQPI
AQQPQGGDHSGNYGYKSENQEFYQDSFGQQW


>Human_Syncrip_Chr6(ENSG00000135316)
ATEHVNGNEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIE
ALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGKVADSSKGPDEAKI
KALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEK
AGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNR
LFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARR
RLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKL
ERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAK
NQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDP
YYGYEDFQVGARGGARGAAPSRGRGAAPPRGRAGYSQRGGPARGGAGPDLLQ--------
-------------------------------

>Zebrafish_Syncrip(1)_Chr20(ENSDARG00000040184)
ATEHINGNEDAMDTAAAVTHSDHFNTLLEAGLPQKVAEKLDEIYLAGLVAHSDLDERAIE
ALKEFNEEGALQVLIQFKESDLSHVQNKSAFLCGVMKTYRQREKQGKVVESTKGPDEAKI
KILLERTGYTLDVTTGQRKYGGPPPESVYTGAQPTVGTEIFVGKIPRDLFEDELVPQFEK
AGPIWDLRLMMDPLSGLNRGYAFLTFCTKEAAQEAVKLCNNHEIRPGKHIGVCISVANNR
LFVGSIPKSKTKEQIVEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARR
RLMSGKVKVWGNLVTVEWADPIEDPDPEVMAKVKVLFVRNLANSVTEEILEKAFGQFGNL
ERVKKLKDYAFVHFNDRDGAVKALTEMNGKELEGEHIEIVFAKPPDQKRKERKAQRQAAK
TQMYDDYYYYGPPQMPPPARGRRGASRGGYSYPPDYYGYEDYYDYYGYDYHNYRGGYDDP
YFGYDDFQAPARGARGGTSPARGRGASAPRGRAGFPQRGGAGGNVGRRQTINQNWGSQPI
AQQPQGGDHSGNYGYKSDNQEFYQDSFGQQW

>Stickleback_Syncrip(2)_GroupXV (ENSGACG00000009124)
ATEHINGNEEPMDTAAAVTHSEHFQTLLEAGLPQKVAEKLDEIYIAGLVSHSDLDDRAIE
ALKEFNEEGALQVLLQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGKVSETNKGPDEAKI
KALLERTAYTLDVTTGQRKYGGPPPESAHSGPQPTVGTEIFVGKIPRDLFEDELVPLFEK
AGPIWDLRLMMDPLSGLNRGYAFVTFCTKDAAQQAVKLCNNNEIRPGKHIGVCISVANNR
LFVGSIPKSKTKEQIVEEFAKVTEGLNDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARR
RLMSGKVKVWGNVVTVEWADPIEDPDPEVMAKVKVLFVRNLASTVTEEILEKAFSQFGKL
ERVKKLKDYAFIHFEERDGAVKALADLNGKDLEGEHIEIVFAKPPDQKRKERKAQRQAAK
THMYDEYYYYGPPHMPPPTRGRGRGGRGGYSYPPDYYGYEDYYDYYGYDYHNYRGGYDDP
YYGYDDFQGSGRVVRGGASQTRGRGGVTPRGRVGFSQRGGP-GTSRGPDLSQ--------
-------------------------------

>Stickleback_Syncrip(1)_GroupXVIII(ENSGACG00000011665)
ATDHVNGNEEPMDTTAEVTRSEHFQALLEAGLPQNVAEKLDELYVAGLVAHSDLDERALE
ALKEFNEEGALQVLVQFKESDLSHVQNKSAFLCGVMKTYRQREKQGKVSDSTKGPDEAKI
KDLLDRTDYTLDVTTGQRKYGGPPPESVYSGAQPNIGTEIFIGKIPRDLFEDELVPLFEK
AGPIWDLRLMMDPLSGLNRGYAFVTFCTKEAAQEAVKLCNNHEIRPGKHIGVCISVANNR
LFVGSIPKSKTKEQIVEEFAKVTEGLSDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARR
RLMSGKVKVWGNVVTVEWADPIEDPDPEVMAKVKVLFVRNLANGVTEELLETSFSEFGKL
ERVKKLKDYAFIHFEERDGAVKALEEMNGKELEGEAIEIVFAKPPDQKRKERKAQRQAAK
TVMYDDYFYYSPSHMPPPVRGRRGGNRGGYSAYPFQA-----------------------
-------------RGRGGSRGSRGGSSPPRGRSNFSPRG--GGVRGGPDASL--------
-------------------------------

>Zebrafish_Syncrip(2)_Chr17 (ENSDARG00000026723)
ATEHINGNDEPVESSAAVTHSEHFQTLLDAGLPRKVAVKLDEIYIAGLVSHSDLDDRAIE
ALKEFNEEGALQVLLQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGKVSDSTKGPDEAKI
KALLERTGYTLDVTTGQRKYGGPPPGSTHAGVQPTIGTEIFVGKIPRDLFEDELVPLFEK
AGPIWDLRLMMDPLSGLNRGYAFVTFCTKEAAQKAVKLCNNNEIRPGKHIGVCISVANNR
LFVGSIPKSKTKDQIVEEFAKVTEGLNDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARR
RLMSGKVKVWGNVVTVEWADPIEDPDPEVMAKVKVLFVRNLASTVTEELLEKTFCQFGKL
ERVKKLKDYAFIHFEERDGAVKALAELHGKDLEGEPIEIVFAKPPDQKRKERKAQRQAAK
TQMYDEYYYYGPPHVHQPTRARG-RGARGYSYPHDYYSYEDYYNYYGYDYHNYRGGYDDP
YYGYDDFQAHVRGGVRVPTLSRGRGSSVSRGRAAFCQRGAPRGSRGGPDQVV--------
-------------------------------

>OUTGROUP_Aedes_aegypti_Hnrnpr_AAEL002879
---------------------------------EQVAGKLDDIYKTGKLAHTELDERALD
ALKEFPVDGALNVLSQFLESNLEHVSNKSAYLCGVMKTYRQKSRASAITVQAKGPDEDKI
KAILERTGYTLDVTTGQRKYGGPPPN--WEGGTPGNGCEVFCGKIPKDMYEDELIPLFEK
CGKIWDLRLMMDPMTGTNRGYAFVTFTSRDAASNAVRELDNYEIKSGKCLKINVSVPNLR
LFVGNIPKSKGKEEILDEFGKLTAGLMEVIIYSSPDDKKKNRGFCFLEYESHKAASLAKR
RLGTGRIKVWGCDIIVDWADPQEEPDEQTMSKVKVLYVRNLTQDTSEEKLKESFEQFGKV
ERVKKIKDYAFIHFEDRDHAVNAMKELDGKDLGGSNLEVSLAKPPDKKKKERARERRTSR
MGIVGEFYSMSPSAMPPPSGASRGAPMRGPMSRGDYAAIGKRKFDGGHQNQGDIKRRY--
------------------------------GAAAAAALG----------NLGNNWGSQPL
PQQPNGGE------------QWYTDSTYSVW


C. Cytosolic 5'-nucleotidase 1 (Ntc51)

>Mouse_Nt5c1b_Chr12(ENSMUSG00000020622)
TEEDEVDEAYWTSPKPKHAITIAVSSRALFNMVDDRKIYEEEGLEKYMEYQLTNENVILT
PGPAFRFVKALQHVNSRLRDLYPDEQDLFDIVLMTNNHAQVGVRLINSVNHY-GLLIDRF
CLTGGKSPIGYLKAYLTNLYLSADSEKVQEAIKE-GIASATMYAGAKDMAYCDTQLRVAF
DGDAVLFSDESEHIAKDHGLDKFFQHETLFENKPLAQGPLKSFLEDLGKLQKKFYAKDER
LLCPIRTYLVTARSAASSGARVLKTLRRWGLEIDEALFLAGAPKGPILVKIRPHIFFDDQ
MFHIESAQKFGTITAHVPYGIAQKRN

>OUTGROUP_Ciona_intestinalis_5-nucleotidase_Chr3q(ENSCING00000005703)
-----VATRRWKIPKPETAIIIALSSRALFDMTEERKIYSEQGLSSYLKHMISRENEPLK
PGSAFPFVQALTCINLRLLELDPNEKHLFDVVLMSNNSAQIGVALINSINYH-ALTIERI
CLTAGKSVTGYLAAYGTDLYLSADSDNVVEALNE-GIAAATVFSGDGAVQSSCEQLRIAF
DGDAVLFSDESEIIAKEHGLTKFFENEAEKADQPLEIGPLQKFAMVLGDVKKKFTDRGII
ENCPIRTYLVTARSAASSGLRALRTLRLWGLDIDEALFLAGAPKGPILEKIKPHLFFDDQ
KRNVDSGLEYGVKAAHVPYGIAQKHT

>Frog_Nt5c1a_Scaf817(ENSXETG00000010949)
FYENLTPTKKPKSPKPHNAITIAVSSRALFLMEEEQKVYQEKGLEEYVRYQLEHENEPFK
PGAAFPFVKALESVNTQLRQLYPESEDLFDIVLMTNNHAQVGVRLINTINHY-NLFIERF
CMTGGNSPIGYLKAYHTNLYLSSDGQKVQEAIEE-GIAAATIFSPSHNVSVHEEQLRVAF
DGDAVLFSDESEQIVKEHGLDMFFEHEKAYENKPLAQGPLKGFLEALGKLQKKFYSKGMR
MNCPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQ
MFHVEGAKEMGTIAAHVPYGVAQRHK

>Chicken_Nt5C1a_Chr23(ENSGALG00000003816) 
-YDNLTPKKKPKSPKPENAITIAVSSRALFRMEEEQKIYNEQGVEAYVKYQLDHENEPFL
PGAAFPFVKALEAVNTQLRELYPDSEELFDIVLMTNNHAQVGVRLINSINHY-DLFIERF
CMTGGNSPIGYLKAYHTNLYLSSDAEKVSGAIEE-GIAAATIFSPSKDLEVSEKQLRVAF
DGDAVLFSDESEQIVKAHGLDMFFEHEKAHENNPLAQGPLKGFLEALGKLQKKFYSKGLR
MECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLKKIRPHIFFDDQ
MFHVEGAKEMGTVAAHVPYGVAQKHK

>Mouse_Nt5c1a_Chr4(ENSMUSG00000054958)
FYDNLSSKKKPKSPKPQNAVTIAVSSRALFRMDEEQRIYTEQGVEEYVRYQLEHENEPFS
PGPAFPFVKALEAVNKRLRELYPDSEDIFDIVLMTNNHAQVGVRLINSINHY-DLFIERF
CMTGGNSPICYLKAYHTNLYLSADADKVREAIDE-GIAAATIFSPSRDVVVSQSQLRVAF
DGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLR
LECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQ
MFHVAGAQEMGTVAAHVPYGVAQNPR

>Human_Nt5c1a_Chr1(ENSG00000116981)
FYDNLAPKKKPKSPKPQNAVTIAVSSRALFRMDEEQQIYTEQGVEEYVRYQLEHENEPFS
PGPAFPFVKALEAVNRRLRELYPDSEDVFDIVLMTNNHAQVGVRLINSINHY-DLFIERF
CMTGGNSPICYLKAYHTNLYLSADAEKVREAIDE-GIAAATIFSPSRDVVVSQSQLRVAF
DGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLR
LECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQ
MFHVAGAQEMGTVAAHVPYGVAQTPR

>Stickleback_Nt5c1_GroupX(ENSGACG00000009267)
-------------PKPENAVTVAVSSRVLFRTELEQRVFEQKGVEEYLRYQIEHENEPFA
PGPAFPFVKALETVNARLRELYPQSEELFDIVLVTYNHAHVGIRLINTINHH-NLFIERF
CMTGGSSPIGYLKAWQTNLYLSADADKVREALAEGGIAAATMFMTEKLTEVSESQLRVAF
DGDAVLFSDESERIFKAHGLDKFFQHEQDNEDTLLDHGPLKGFLEALGKLQKKFYAKGQR
LDCPIRTYLVTARSAASSGIRALKTLRAWGLEIDEALFLAGAPKGPMLEKIRPHIYFDDQ
MFHVEGAAEMGTVAAHVPYGVAQKHN

>Zebrafish_Nt5c1a_Chr19(ENSDARG00000035883)
-IQKLYAKRNRSRPKPENAVTIAVSSRVMFRTEKEQKVFEQKGIEEYLRYQVEHENEPFA
PGPAFPFVKALEAVNTRLRELYPESEELFDIVLVTYNHAHVGVRLINTINYH-NLFIERF
CMTGGSSPIGYLKAFHTNLYLSADAEKVQEALSE-GIAAATMFMPEKQIEVSETQLRVAF
DGDAVLFSDESERIFKAHGLDKFFEHERENENRLLDHGPLKGFLEVLGKLQKKFYAKGHR
LDCPIRTYLVTARSAASSGIRALKTLRAWGLETDEALFLAGAPKGPMLEKIRPHIYFDDQ
MFHVEGAVEMGAIAAHVPYGIAQKY-

>Stickleback_Nt5c1a_GroupXV(ENSGACG00000006693)
------PPRKPKPPKPENAVTIGVSARVLFNMETEQQIYERQGLEEYIKYQVEHETQPFT
PGPAFSFVKALEAVNAQLRELYPESEELFDVVLMTNNHAYVGLRLINTINHH-QLFIERF
CMTGGNSPIGYLKAYHTNLYLSADPVKVREALEE-GIAAATMFTPEKMAEVSESQLRVAF
DGDAVLFSDESERIYKAHGLDKFFEHEKAHENKLLDHGPLKGFLEALGKLQKKFYGKGQR
MECPIRTYLVTARSAASSGTRALKTLRSWGLEIDEALFMAGAPKGPMLEKIRPHIFFDDQ
MFHVEGAAEMGTVACHVPYGVAQGVT

>Zebrafish_Ntc51_Chr17(ENSDARG00000070590)
-------------PKPQNAITIAVSSRALFNMDLEQDIYEQQGMEDYLNYQIQHEMEPFA
PGPAFPFIKAVEAVNTRLRELYPDSEELFDVVLMTSNHAHVGLRLINSINHH-QLFLERF
CMTGGNSPIGYLKAYHTNLYLSADSLKVREAIEA-GIAAATVFSPGKITEVPETQLRVAF
DGDAVLFSDESERIYKAHGLDKFFEHEKAHENKPLDHGPLKGFLEALGKLQQKFYAKGQR
LDCPIRTYLVTARSAASSGTRALKTLRSWGLETDEALFLAGAPKGPMLEKIRPHIFFDDQ
MFHVEGAAELGTVAAHVPYGIAQKIP

>Stickleback_Nt5c1b_GroupXVIII_(ENSGACG00000008368)
HFDNLK-TNKPRPPKPQYAVTIAVSSRTLFNMVTERKIYEDQGLEEYVAYQRDHENEPLM
PGPAFPFVKALMTVNARLRQLYPDSEELFDIVLMTNNHAQVGVRLINSINHY-DLTIERF
CMTGGESPTGYLEAYMTNLYLSKDSEKVSEAIEE-GIAAATMFMAVKENELSDTQLRVAF
DGDAVLFSDESEIIVKEGGLDTFFAHEKKFENTPLAQGPLKCFLEALGKLQRKFYAKNER
LNCPIRTFLVTARSAASSGARVLKTLRSWGLEIDEALFLAGAPKGPLLQKIKPHIFFDDQ
MFHIEGARELGTISAHVPYGIGQKYN

>Zebrafish_Ntc51b_Chr20(ENSDARG00000033742)
--YENLKSKKPRPPKPKNAVTIAVSSRTLFDLTAERKIFEEEGVEKYVQHQQDNENQPLN
PGPAFPFVKALMTVNERLRELYPESEELFDIVLMTNNHAQVGVRLMNSINHY-DLTIERF
CMTGGQSPIGYLKAYMTNLYLSRDSKKVGEAIEE-GIAAATMFKSDVETQLSETQLRVAF
DGDAVLFSDESEIIVKQHGLDTFFEHEKQHENKPLAQGPLKCFLEALGKLQKKFYAKNER
LNCPIRTFLVTARSAASSGARVLKTLRSWGLEIDEALFLAGAPKGPLLQKIRPHIFFDDQ
MFHIEGAKEMGTIAAHVPYGIGQKYN

>Zebrafish_Ntc51_Chr13(ENSDARG00000018153)
LFDNSKTTKKPRPPKPSNAVTIAVSSRTLFNMIKERKVFEEEGLERYVAHQLELEDQPFP
PGVSFPFVKALMNVNARLRDLYPDSEELFDIVLMTNNHAQVGVRLINSINHYADLTIERF
CMTGGESPIGYLKAYMTNLYLSKDSMKVQEAIEE-GIAAATMFTGDSENELSDTQLRVAF
DGDAVLFSDESEIIVKEHGLDTFFKHEKEFENKPLAQGPLKCFLEALGKLQRKFYAKNQR
INCPIRTYLVTARSAASAGARVLKTLRSWGLEVDEALFLAGAPKGPLLQKIKPHIFFDDQ
MFHIEGAQELGTIAAHVPYGIGQKYH

>Frog_Nt5c1b_Scaf100(ENSXETG00000015581)
FYDKLAPKKKPRLPKPQNAITIAVSSRTLFNMVEERKIYEQLGVEKYVQYQQDHETEPLK
TGPAFPFVKSISGTSTYL------TEKVYVVSLF--NAKPYSCRIITFLLFHIGLNIERF
CLTGGKSPIGYLKAYLTNLYLSADSEKVQEAIAE-GIAAATMFIAKKDTVLSEKQLRVAF
DGDAVLFSDESEQIVKEHGLDTFFEHEKAFENKPLAQGPLKCFLEALGKLQRKFHAKDAR
LNCPIRTYLVTARSAASSGARALKTLRSWGLEVDEALFLAGAPKGPILEKIRPHLFFDDQ
MFHIEGAQDLGTIAAHVPYGIGQKYN

>Chicken_Nt5c1b_Chr3(ENSGALG00000016471)
AFYDNLVTKRPRPPKPQHAITVAVSSRALFDLVEERRIYEEQGVEKYVEYQQENENVTLK
PGPAFHFVKALEHVNARLLELYPDDEERFDIVLMTNNHAQVGVRLINSINHY-GLTIERF
CMTGGKSPIGYLTAYLTNLYLSADSEKVQEAIEA-GIAAATMFTANKDVAYSDTQLRVAF
DGDAVLFSDESEQIVKEQGLDKFFEHEQLNENKPLAQGPLKGFLEDLGKLQKKFYAKNER
LNCPIRTFLVTARSAASSGARVLKTLRSWGLEIDEALFLAGAPKGPILVKIRPHIFFDDQ
MFHIEGAQKLGTIAAHVPYGVAQKYQ

>Human_Nt5c1b_Chr2(ENSG00000185013)
FYEKNPSCSRPWPPKPKNAITIALSSCALFNMVDGRKIYEQEGLEKYMEYQLTNENVILT
PGPAFRFVKALQYVNARLRDLYPDEQDLFDIVLMTNNHAQVGVRLINSVNHY-GLLIDRF
CLTGGKDPIGYLKAYLTNLYIAADSEKVQEAIQE-GIASATMFDGAKDMAYCDTQLRVAF
DGDAVLFSDESEHFTKEHGLDKFFQYDTLCESKPLAQGPLKGFLEDLGRLQKKFYAKNER
LLCPIRTYLVTARSAASSGARVLKTLRRWGLEIDEALFLAGAPKSPILVKIRPHIFFDDH
MFHIEGAQRLGSIAA---YGFNKKFS


D. Proline-rich nuclear receptor coactivator (Pnrc)

>Chicken_Pnrc2_Chr23(ENSGALG00000004122)
MGGGERFNVPVPQS-RNITKNHQQLKNRQKNKDQN-SQMKKTYMKKERGHGCNSLSGAWQ
AMQKAGKNNVHFPCNQNWSPNLSNRNLFFSPQTNQNYAGAKFSEPPSPSVLPKPPSHWVP
VSFKPSDKEIMTFQLKTLLKVQA

>Zebrafish_Pnrc2_Chr16(ENSDARG00000053291) 
MGGGERYNIPDRPA---PKKSQPVSRGKQRSRDQN-GVMHSAASGALGVTSYSWSPEARQ
AVSVDKKVRFATPYDQNWES---HLNKLLSAQCGQNYAGAKFSEPPSPSVLPKPPSHWVS
LPMG-DHRELMTFQLKSLLKVQA

>Human_Pnrc1_Chr6(ENSG00000146278)
MGKSEKIALPHGQLVHGIHLYEQPKINRQKSKYNL-PLTKITSAKRNENNFWQDSVSSDR
IQKQEKKNTENIKN--SHLK---KSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHWMG
STVENQNRELMAVHLKTLLKVQT

>Stickleback_Pnrc1_GroupXVIII(ENSGACG00000012062)
GGRPERGAAGDQIPPNATPRSHKPKQGRS-------------------------PGAARP
AKKKDKSSPGKPLPLHQRGPD--AAADEGLKDGEKVYAGAKFSEPPSPSVLPKPPSHWVG
-----------------------

>Zebrafish_Pnrc1_Chr20(ENSDARG00000043904)
GSQISRASILNCSRLEQTTDNLNRRTHQS--------------------------KHQIN
ARQDKPTSTEKSPE--NILK---QGNASTSSDAEKTYAGAKFSEPPSPSVLPKPPRHWVG
DHAPQCSREQMSEHLKTLLKVQT

>Frog_Scaf408_Pnrc2(ENSXETG00000005273)
MGGGERFNIPG-QH----RNNLGKQINRQKLLERNNQKMN-TSLSKDRVRGCGT-SLAWQ
AMQNGVNNNNTRSSNQNWSAGFPASKNFFTDQDNQNYAGAKFSEPPSPSVLPKPPSHWVL
LSCSPAEKELMSFQLKTLLKVQA

>Mouse_Pnrc2_Chr4(ENSMUSG00000028675)
MGGGERYNIPDPQS-RNASKNQEQQ-NRQKSKDQNSSQTKIAHKKKERGHGYNPAAAAWQ
AMQNGGK-TKSLSNNSNWNAGLSSPSLLFKSQASQNYAGAKFSEPPSPSVLPKPPSHWVH
VSLNPSDKETMTFQLKTLLKVQV

>Human_Pnrc2_Chr1(ENSG00000189266)
MGGGERYNIPAPQS-RNVSKNQQQL-NRQKTKEQN-SQMKIVHKKKERGHGYNSSAAAWQ
AMQNGGK-NKNFPNNQSWNSSLSGPRLLFKSQANQNYAGAKFSEPPSPSVLPKPPSHWVP
VSFNPSDKEIMTFQLKTLLKVQV

>Stickleback_Pnrc2_GroupXX(ENSGACG00000013653) 
MGGGERYNIPERPL---PKKNQ-LGRAKQRGRDQ---IHHLGHRRNDKVAAYHRSQEARQ
AASAE-KVRFATNYDHNWEGAVSHLNTLLATQGSPSYAGPKFSEPPSPSVLPKPPSHWVS
FPMGPDHREMMAFQLKSLLKVQA

>Chicken_Pnrc1_Chr3(ENSGALG00000015780)
MGKTEKAATPHGQPVHGLHLCEQPKINRQKNKCNV-PLTKIASAKKIE-NFWQDSVPPEI
IQKQEKKNTENFRN--AKSK---KPITLTDANQKENYAGAKFSDPPSPSVLPKPPSHWVG
GTAELQNRELMAVHLKTLLKVQV

>Mouse_Pnrc1_Chr4(ENSMUSG00000040128)
MGKSEKIALPHSQLVHGIHLCEQPKINRQKSKYNL-PLTKITSAKRNESDFWQDSASSDR
MQKQEKKNTENIKS--NHLK---KSAFLTEVSQKENYAGAKFSDPPSPSVLPKPPSHWMG
STAENQSRELMAVHLKTLLKVQT

E. Cannabinoid receptor (Cnr) family

>Ciona_intestinalis_Cannabinoid_receptor(NP_001027653)  
RIPT----LSTLSTIMMN----GS-----EDSHVLNSEGNAIHVVGTILSLIIIVENALV
LMALTMERRRFKLILFVFINSLAASDLLSGIVFLYTFLFNDLLSFTASAPSWVFRKAFLI
ASLLVSLGSLQLIALDRFVSVAWPLEHEKFISRRRAVILVVLNWVLGAALIIAPVAGWNC
IGIVLCFARMAVREEKNLAVFMVLVFVVFILCWMPSVILLCIDSSMPSVRISDDLFDICS
FPALLNSIINPWLYAIKLKSCRTVLVQWLCRCQSDPSDVGAANVGEFQ

>Zebrafish_Cnr1_Chr20(ENSDARG00000009020)
KSVLDGVAETTFRTITSGLQYIGSCGENFMECFMILSQQLAIAVLSLTLGTFTVLENLVV
LCVILQSRTLRCRPSYHFIGSLAIADLLGSVIFVYSFLDFHVFHRKDSPNVFLFKLGGVT
ASFTASVGSLFLTAIDRYVSIHRPLSYRRIVTRTKAVIAFCMMWAISIIIAVLPLLGWNC
VRMLRRDGTKVQRMDIRLAKTLVLILVVLVICWGPLLAIMVYDLFWRMGDNIKTVFAFCS
MLTLLNSTVNPIIYALRSKDLRRAFLAACQGCRAAESTVKIASVSAET

>Chicken_Cnr2_Chr23(ENSGALG00000004120)
-------INCKMYENA-------SCNVSSMECFMVLAQKISTATLCGLFGTLGIFENCLV
LYLIFSSPGTRRKPSYIFISSLALADLLASIIFVRSFVNFHVFNTDSSKELFLLKLGGVN
TSFMASLSSLLLMALDRYISISYPSKYKLLVTRKRAWTALGVLWVTCVATAFLPLMGWNC
VCAYARMGKHQVRMDVMLAKTLVMVLTVLVLCWLPALILMIYSIFVNLNNHLRKVFAFCS
TLCLLNSMVNPIIYALRSKELYSSLRMRLSQCRS--ST----------

>Frog_Cnr2_Scaffold403(ENSXETG00000005272)
-------------------------------IFLCA-------------------GQMFC
LCDYYSAAMRWRKPSYIFLMSLALADFLASMVFSYSFVDFHVFHGAGTHAVFLFKLGGVT
ASFTASLGSLLLMAFDRYVSIHKPSMYKSKVTRKRALLALAGMWLITMFIAYLPLMGWN-
TLIIYSAVYMEQRLDIMLAKTLALVLLVLVICWSPVLILMMHSLLFSLDRSIKTIFAFCS
TLCLVNSMVNPMIYAWRSRELHRKLIKGFQNIKN--ST-----VGEET

>Human_Cnr2_Chr1(ENSG00000188822)
-------EECWVTEIAN-----GSDGLDSMKDYMILPQKTAVAVLCTLLGLLSALENVAV
LYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVT
MTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTC
HVLWK-GHQDRQRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCS
MLCLINSMVNPVIYALRSGEIRSSAHHCLAHWRS--STEADGSRDLDL

>Zebrafish_Cnr2_Chr16(ENSDARG00000039970)
KLEQDQEATTVLYSNLS-TQNISTDKSLCLQCYMVLQEQKAISSICFLAGPVTFLANILV
LLTIASSTALRRRPSYLFISSLALADMFASCFFTISFLDFHLLSQRDDANLYLFKLGGVT
MAFTGSVGSLLLTALDRYLCIYQASNYKLLLTRTRAKLAILFLWCVTIILSFLPLMGWRC
FLIIVAEANMGGRMDIQLAHTFSLILLILAICWLPVLSFMVVDVRVTLTNKQQRMFAFCS
TLCLVNSCVNPLLYALRCRELRGEMLALIECCRS-----------ADR

>Human_Cnr1_Chr6(ENSG00000118432)
KSILDGLADTTFRTITTDLLYVGSCGENFIECFMVLSQQLAIAVLSLTLGTFTVLENLLV
LCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVT
ASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNC
VRMIQREDGKVQRMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCS
MLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCRAAESTVKIASVSTDT

>Chicken_Cnr1_Chr3(ENSGALG00000015789)
KSILDGLADTTFRTITTDLLYVGSCGENFMECFMILSQQLAIAVLSLTLGTFTVLENLLV
LCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVT
ASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCVMWTIAIVIAVLPLLGWNC
VRMLQREDGKVQRMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCS
MLCLLNSTVNPIIYALRSKDLRHAFRSMFPTCRAAESTVKIASVSTDT

>Mouse_Cnr1_Chr4(ENSMUSG00000044288)
KSILDGLADTTFRTITTDLLYVGSCGENFMECFMILSQQLAIAVLSLTLGTFTVLENLLV
LCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVT
ASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNC
VRMIQREDGKVQRMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCS
MLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCRAAESTVKIASVSTDT

>Frog_Cnr1_Scaffold681(ENSXETG00000005380)
KSIMGGFADTTFRTITTDFLNMGPCGKNFMECFMILSQQLVIAALSIILGTFTVLENMLV
LVVILQSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVT
ASFTASVGSLFLTAIDRYISIHRPLSYKRIVTRTKAVIAFCMMWTIAIVIAVLPLFGWNC
VRMLQREDGKVHRMDIRLAKTLVLILVVLIICWGPLMAIMVYDVFGKINKTIKTVFAFCS
VLCLLNSTVNPIIYALRSKDLRSAFCSMFPSCRAAESTVKIASVSTDT

>Stickleback_Cnr1(1)_GroupXVIII(ENSGACG00000008279)
KSVLDGVADTTFRTITSGLQFLGSCGENFMECFMILSQQLAVAVMSLTLGTFTVLENLVV
LGVIFRSRTLRCRPSYHFIGSLAVADLLGSVIFVYSFLDFHVFHRKDSPNVFLFKLGGVT
ASFTASVGSLFLTAIDRYISIHRPLSYRRIVTRTKAVIAFCVMWTISIVIAVLPLLGWNC
VRMLSRDGTKVQRMDIRLAKTLVLILAVLIICWGPVLAIMVYDLFWRMDNDSKTVFAFCS
MLCLLNSTVNPIIYALRSKDMRHAFLSSCQACRAAESTVKIASVSTET

>Stickleback_Cnr1(2)_GroupXV(ENSGACG00000009189)
KMALHRIAGTAMSSLTTGVQYLGSCGEDFMECFMILSQQLAVAILALTLGTFTVLENLMV
LCVILHSRTLRSRPSYHFIGSLAVADLIGSIIFVYSFLDFHVLHRKDSPSIFLFKLAGVI
ASFTASVGSLFLTAIDRYISIHRPMAYKRIVTKTKAVIAFSVMWAISIVFSLLPLLGWNC
VRMLSREGTKVQRMDLRLAKTLVLILVALIICWGPLLAIMVYDLFGKVNDFIKTVFAFCS
MLTLLNSTVNPVIYAMRSKDLRRAFVNICHVCGVVGGRVKVASGMTET

>Mouse_Cnr2_Chr4(ENSMUSG00000062585)
-------EGCRETEVTN-----GSGGLEFMKEYMILGQQIAVAVLCTLMGLLSALENMAV
LYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVT
MTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTC
YVLWK-EHQDRQRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCS
MLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWRS--STEADV------

>Stickleback_Cnr2_GroupXX(ENSGACG00000013656)
-------------------------------------EQTAIGSICFLAGPITFLENALV
LGVIAATASLRQRPTYLFIASLALADVFASCFFTTSFLDFHLFRRSDGPTAYLFKLGGVT
MAFTSSVGSLLLTALDRYLCIQQASSYKLLLTRRRAVLGLLMLWTATILVSFLPLIGWRC
ALILCAELTMTGRIDIRLARTFGLILIILVSCWLPALSFMLADVSVVLTRTQQRAFAFCS
TLCLVNSAVNPLLYALRCRELRVALLQLVQRLEDG-------------

F. Glycoprotein endo-alpha-1,2-mannosidase (Manea) family

>Amphiouxus_Manea/Maneal-like(XP_002248661)
HVFYYPWYGNPEHNGKYLHWNHNLIPHWSKQEAKKWPTGRHEPPNDVGANFYPSLGAYSS
SDPAVIEHHMQQMRYAGIGVFAVSWYPPEQADNEGQPSDSLIPALLDAAQKYSLKVAFHI
EPYEGRTDWSLQHSVRYIVDTYGAHPAFYRHTRNGKNLPLFYIYDSYNLPAKDWKNLLSP
SGSHTIRNTAYDAIFLGLLVEMKHKNEIVQGGFDGFYTYFATNGFTYGSSFTNWKTLKQF
ANQNKIMFIPSIGPGYVDTRVRPWNERNTRKRLNGKYYNDAFQAAFDVNPEIISVTSFNE
WHEGTQVEMAMPKYNDYTPNSPEFYLKLTRNWSEKF

>Chicken_Manea_Chr3(ENSGALG00000015590)
HIFYYSWFGNPQFDGKYIHWNHPLLPHWDPKIANNYPKGRHNPPEDIAANFYPELGSYSS
KDTSVIEAHMKQMLSASIGVIALSWYPPGMADENGEPTDDLVPIILDYASKYNLKVTFHI
EPYKDRDDRSMYHNVKYIIDKYGAHPAFYRHTSTGRSLPMFYVYDSYVTIPEIWANLLTV
SGSQTIRNTPYDALFIALLVEERHKHDIHRSGFDGMYTYFATNGFSYGSSHHNWASLKAF
CDSNNLMFIPSVGPGYIDTSIRPWNNHNTRNRVNGKYYETAFNAALLVRPEIISITSFNE
WHEGTQIEKAVPKYLDYKPHKPNVYLELTQKWSEKY

>Stickleback_Maneal(2)GroupX (ENSGACG00000007831)
HIFYYLWYGSPSMDNKYIHWDHVLVPHWDPKIAASHAQGRHTPPDDIASSFYPELGPYSS
RDPKVLESHMAQIEAAAAGVLVLSWYPPGMAEDHGEPTEDLVPAVMDAAHRHSIKVAFHM
QPYKGRTDQSMHDNIKYIIDRYGEHGAFYRFSGTGRVLPLFYVYDSYLMAPESWAEVLTL
KGSRSIRGTPYDGVFVALLVEERHKHDILASGFDGVYTYFASNGFSFGSSHQNWKAIKEF
CDVNNLLFVPSVGPGYVDTAVRPWNNHNTRNRVNGRYYDTSLQAALSVRPEIVAVTSFNQ
WHEGTQIEKAVPKYLDYQPNLADHYLQLTRQWAENF

>Zebrafish_Maneal_Chr19(ENSDARG00000056450) 
HIFYYLWYGSPQMDSSYIHWDHVLVPHWDPKIAASHPKGRHNPPDDIASSYYPELGPYSS
RDPEVIESHMAQIEAAAAGVVVLSWYPPGVADEHGKPSEDLVPAVMDAAHKHSIKVAFHL
QPYKGRTDISVHDNIKYIIDTYGTHGAFYRFSSTGKILPLFYVYDSYLTPPETWAELLTI
RGSHSLRGTPYDGIFIALIVEERHKQDILAGGFDGMYTYFASNGFSFGSSHQNWKAIKAF
CDKNNLLFVPSAGPGYMDTAVRPWNNHNTRNRVNGRYYETSLQAAMSVRPDIITITSFNE
WHEGTQIERAVPKYLDYKPHQPDHYLELTKKWAEHF

>Stickleback_Maneal(1)GroupXX(ENSGACG00000013887)
HIFYYTWYGNPSMDGKYIHWDHILVPHWDPKIASSYPRGRHAPPEDIGSSFYPELNPYSS
RDPDVLESHMEQIGASAAGVLVMSWYPPGLADDNGEPAEDLVPAVLDAAYRHNLKVAFHI
QIYRGRNDQSVHDNIKYIIDRYGEHGAFYKCSSTGKSLPLFYIYDSYLTPPESWSELLTP
AGSHSVRGSAYDSIFIALIVEERHKHDILAGGFDGMYTYFASNGFSFGSSHQNWKSIKAF
CDGNNLLFIPSVGPGYIDTSIRPWNNHNLRNRVNGRYFETALQAALDVRPEVVAITSFNE
WHEGTQIERATPKYLDYQPHGPDHYLELTRRWVEQF

>Frog_Maneal_Scaf422 (ENSXETG00000011508)
HIFYYMWYGNPKFDGNYIHWDHVMVPHWDPKISASYPKGRHSPPEDIGSSFYPELGPYSS
KDPEVLEEHMRQLRAAAIGVLVLSWYPPGTADENGEAVEDLVPLILEAALKHNIKVAFHI
QPYKGRDDRTLHDNIKYIIDNFGSHPAFYRYTSTSKSLPLFYIYDSYLTPPESWANLLTL
TGSHTVRNTPYDAVFIGLLVEEGHKHDILTAGYDGIYTYFASNGFSYGSSHQNWKSIKSF
CDTNNLMFIPSVGPGYIDTSIRPWNNHNTRNRVNGKYFETALQAALTVRPEIVSITSFNE
WHEGTQIEKAKPKYLDYTPHQPDLYLVLTRKWAEHF

>Mouse_Maneal_Chr4(ENSMUSG00000042763)
HAFYYSWYGSPRREGHYIHWDHVMVPHWDPKISASYPRGRHSPPDDLGSSFYPELGPYSS
RDPDVLREHMTQLKEAAIGVLVLSWYPPGMADDNGEPTDDLVPAILDTAHQYNIQVAFHI
QPYKGRDDITVHDNIKYIIDTYGSHGAFYRYNSMGKSLPLFYIYDSYLTSPEAWAHLLTQ
NGPHSIRNTPYDGVFIALLVEESHTHDILAAGFDGMYTYFASNGFSFGSSHQNWKAVKNF
CDTNNLMFIPSVGPGYIDTSIRPWNNHNTRNRVNGKYYETALQAALTVRPEIVSITSFNE
WHEGTQIEKAVPKYLDYLPHQSSLYLELTRRWAEHF

>Human_Maneal_Chr1(ENSG00000185090)
HAFYYSWYGSPRREGHYIHWDHVMVPHWDPKISASYPRGRHSPPDDLGSSFYPELGPYSS
RDPEVLREHMTQLKEAAIGVLVLSWYPPGMADDNGEPSDDLVPAILDTAHQYSIQVAFHI
QPYKGRDDITVHDNIKYIIDTYGSHGAFYRYNSMGKSLPLFYIYDSYLTSPEAWAHLLTP
NGPHSIRNTPYDGVFIALLVEEGHTHDILAAGFDGMYTYFASNGFSFGSSHQNWKAVKNF
CDANNLMFIPSVGPGYIDTSIRPWNNHNTRNRVNGKYYETALQAALTVRPEIVSITSFNE
WHEGTQIEKAIPKYLDYLPHQPSLYLELTRRWAEHF

>Chicken_Maneal_Chr23(ENSGALG00000001653)
HAFYYAWYGSPRFEGRYLHWDHALVPHWDPKVSASYPRGRHRPPDDIGSSFYPALGPYSS
RDPAVVDEHMGQLRAAAIGVLVLSWYPPGLADDNGEPSDSLVPFILDAAQRYAIKVTFHI
QPYKGRDDHTVHENIKYIMDKYGSHAAFYKYTSTGRSLPLFYIYDSYLTPAESWANLLTP
SGSHSLRNTAYDAVFIALLVEEGHKEDILSAGYDGMYTYFASNGFSFGSSHQNWKAIKTF
CDSNNLMFIPSVGPGYIDTSIRPWNNHNTRNRVNGKYYETALQAALTVRPEIVSITSFNE
WHEGTQIEKAVPKYLDYLPHQPNMYLELTRRWAEHF

>Stickleback_Manea_GroupXV(ENSGACG00000010260)
HAFYYVWYGNPKFDGKYIHWNHPQLPHWDLKVAQGYPQGRHIPPDDIGANFYPSLGAYSS
RDPSVIESHMQQLRTAAIGVLGVSWYPPNMNDDNGEPVDDIVPLLLEVAHKYHIKVAFHI
EPYKDRDEVSMFANVKYIIDKYGEHPAFFKYTNAGKLLPLFYVYDSYLINSEQWAKLLKH
TESNSIRNTPYDAIFIALLVEEKHKRDILTAGFDGLYTYFATNGFSYGSTQRNWESIKAF
CEDNNLIFIPSVGPGYIDTSIRPWNFQNTRNRINGKYYETSLSAALQARPDFISITSFNE
WHEGSQIEMAVPKYLDYLPNKPAIYLEITRKWASIF

>Zebrafish_Manea_Chr17(ENSDARG00000001898)
HAFYYVWYGSPQFDGKYVHWDHPLLPHWDPKVASSYSTGRHQPPEDIGANFYPALGPYSS
RDPAVLEEHMRQLRMAAVGVLAVSWYPRSMKDDNGEEIDSLLPLILDAADKNQLKVVFHI
EPYKGRDDANMRENIQYIVDRYGNHPAFYKYTSTGKLLPLYYIYDSYLQTPDVWAQLLKP
NGISTVRNTPYDGIFIALLVEERHKKDILTAGFDGLYTYFATNGFTYGSSHHNWRTIKTF
CDYNDLVFIPSVGPGYIDTSIRPWNAQNTRNRINGKYYETAFNAAVDARPQIISITSFNE
WHEGTQIEKAIPKYLDYLPHKPTVYLEITQRWARKF

>Mouse_Manea_Chr4(ENSMUSG00000040520)
HAFYYSWYGNPQFDGKYIHWNHPVLEHWDPRIAKNYPQGQHSPPDDIGSSFYPELGSYSS
RDPSVIETHMKQMRSASIGVLALSWYPPDSRDDNGEATDHLVPTILDKAHKYNLKVTFHI
EPYSNRDDQNMHQNIKYIIDKYGNHPAFYRYTRTGHSLPMFYVYDSYITKPTIWANLLTP
SGSQSVRSSPYDGLFIALLVEEKHKNDILQSGFDGIYTYFATNGFTYGSSHQNWNNLKSF
CEKNNLMFIPSVGPGYIDTSIRPWNTQNTRNRVNGKYYEVGLSAALQTHPSLISITSFNE
WHEGTQIEKAVPKYLDYRPHKPSLYLELTRKWSEKF

>Human_Manea_Chr6(ENSG00000172469)
HVFYYSWYGNPQFDGKYIHWNHPVLEHWDPRIAKNYPQGRHNPPDDIGSSFYPELGSYSS
RDPSVIETHMRQMRSASIGVLALSWYPPDVNDENGEPTDNLVPTILDKAHKYNLKVTFHI
EPYSNRDDQNMYKNVKYIIDKYGNHPAFYRYTKTGNALPMFYVYDSYITKPEKWANLLTT
SGSRSIRNSPYDGLFIALLVEEKHKYDILQSGFDGIYTYFATNGFTYGSSHQNWASLKLF
CDKYNLIFIPSVGPGYIDTSIRPWNTQNTRNRINGKYYEIGLSAALQTRPSLISITSFNE
WHEGTQIEKAVPKYLDYRPHKPGLYLELTRKWSEKY

>Frog_Manea_Scaf115(ENSXETG00000001060)
HIFYYTWFGNPQFDGKYIHWNHPLLKHWDVKIANSFPLGNHNPPDDIGANFYPELGPYSS
RDPSVIDAHMKQIRSSSIGVISVSWYPPGMSDDNGEPTDDIIPTILDKAHNYGLKVTFHI
EPYRNRDDYSLHNNVVYIIDKYGSHPAFYKYTENGKNLPMFYIYDSYITTPGTWANLLTS
SGSQSIRNTPYDGIFIALLVEEKHKHDILRGGFDGLYTYFATNGFSYGSSHHHWSSLKEF
CDTNNLIFIPSVGPGYIDTSIRPWNFQNTRNRINGKYYETAMNAALLVRPKIISITSFNE
WHEGSQIEAAVPKYEDYLPHKPNIYLELTRKWSEKY


G. Potassium voltage-gated channel (Kcnq) family

>Human_Kcnq1_Chr11 (ENSG00000053918)
THVQGRVYNFLERPTGKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLV
VFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFAT
SAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE
KRVEFGSYADALWWGVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFA
LKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSTWKIYKKKFKGVTPGEKMLTVPY
DSSVRKSP----------TLLSQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVI
EQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKTIGARLNRVEDKVTQLDQRLALI
TDMLHQLLSLH

>Human_Kcnq3_Chr8(ENSG00000184156)
RRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAI
FIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGN-VLA
TSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVE
KKEEFETYADALWWGITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLA
LKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRATWRFYLDRVRGSNTKGKLF---S
PSKEPKPVGLNNKERFRTAFREDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVI
EQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSMMGKFVKVERQVQDMGKKLDFL
VDMHMQHMERL

>Mouse_Kcnq5_Chr1(ENSMUSG00000028033)
RRVQNYLYNVLERPRGWAFVYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMI
VVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFAT
SALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVE
KNKEFSTYADALWWGITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA
LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSATWKPHKERVRGQSIKSRQASVGS
PTKVQKSWSFNDRTRFRPSLREDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVI
EQYSAGHLDMLCRIKSLQTRVDQILGKGQMTSDKKSRSMLARVVKVEKQVQSIESKLDCL
LDIYQQVLRKG

>Ciona_intestinalis_Kcnq2/3/4/5_Chr2q_(ENSCING00000011369) 
LQMRIEAYNFLERPNFYSIFYHTFTFLLVFGCLVLSVLSTIPNHMEKANKILFIVEVLIL
ILFGLELGVRIWSAGCRCRYQGFLGRMRFCKKPLCVIDIIVVMSSFVVLCIGSNGHMFAA
TAMRSLRFLQILRMVRMDRRGGSWKLLSSVVRAHSKELITAWYIGFLALIFASFLVYQAE
KSKEFETFADALWWGITLTTIGYGEKVPITWLGRLIASVFAILGISFFALPAGILGSGFA
LKVQEQNRQKHFARRRMPAAYLLQCMWRCYAADKNSATWKPHSRRQTGGSSKTTVVSPPS
RNEIVKSQSLAERLTDRISRQTELTEQHKVAIRAIRMMKFFVARRKFKEALRPYDVKDVI
EQYSAGHVDMLSRIKLLQNRVDCILGIGTDGGAVGNTSINSRLHSVEIDVKKVDQKLDQV
IQLLTSDKKNG

>Stickleback_Kcnq1_GroupII(ENSGACG00000017155) 
AHIQGQVYNFLERPSGKCFVYHFTVFLIVLACLILSVLSTIDQYQALAHTTLFWVEIVLV
VFFGVEYFVRLWSAGCRSKYVGICGRLRFARKPISIIDLIVVVASIIVLSVGSKGQVFAT
SAVR-LKFSDNVTTSHEKDPIGQWIDL-SVLYCVFQELITTLYIGFLSLIFSSYFVYLAE
KYSEFENYADALWWGVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFA
LKVQQKQRQKHFNRQIPAAACLIQTSWRCFAVENFDVTFKKFRKPRSGPTSPTVPSITYN
STFEASAG----------LLDSQLTESHRRAIRVIQRMRYFVARRNFQQARKPYDVRDVI
EQYSQGHLNLMVRIKELQRRLDQSIGRQTLFQSGSDRSIGSRLNRMEDKITHMDHTLNRI
AESLTSVLHRR

>Frog_Kcnq1_Scaffold216(NM_001122875) 
TNIQGRVYNFLERPTGKCFVYHFTVFLIVLICLIFSVLSTIQQYNNLATETLFWMEIVLV
VFFGAEYVVRLWSAGCRSKYVGVWGRLRFARKPISVIDLIVVVASVIVLCVGSNGQVFAT
SAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE
KEYQFGSYADALWWGVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFA
LKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDATWKIYKKKIRGSTD-KMLNIPHY
ENTVRKPF----------GFLSELKEHHRAAIKVIRRMQYFVAKKKFQQARKPYDVRDVI
EQYSQGHLNLMVRIKELQRRLDQSLGKPSLFLSVSDKTIGSRLNRVEDKVTQMDHKLNLI
TDMLHHLLTNQ

>Mouse_Kcnq1_Chr7(ENSMUSG00000009545)
THIQGRVYNFLERPTGKCFVYHFTVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLV
VFFGTEYVVRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFAT
SAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE
KRIEFGSYADALWWGVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFA
LKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDATWKIYKKKFKGMSPGEKMFNVPY
DSSVRKSP----------TLLSQLRDHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVI
EQYSQGHLNLMVRIKELQRRLDQSIGKPSLFIPISEKTIGARLNRVEDKVTQLDQRLVII
TDMLHQLLSMQ

>Chicken_kcnq1_Chr5(ENSGALG00000006472)
SNIQGRVYNFLERPTGKCFVYHFTVFLIVLICLIFSVLSTIEQYAALATGTLFWMEIVLV
VFFGTEYVVRLWSAGCRSKYVGIWGRLRFARKPISIIDLIVVVASMIVLCVGSKGQVFAT
SAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAE
KETEFGSYADALWWGVTVTTIGYGDKVPQTWIGKTIASCFSVFAISFFALPAGILGSGFA
LKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSTWKIYKKKFKGPSSPDKMLTVPY
ENSVKKSP----------TFLSQLREHHRAAIKVIRRMQYFVAKKKFQQARKPYDVRDVI
EQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKTIGARLNRVEDKVTQMDQKLNLI
TEMLHRLVSSH

>Ciona_intestinalis_Kcnq1_Scaf165(XM_002121623) 
RHFQQQAYNFLERPTGKCFVYHVLVFMMVLICLIFSVLSTIEGQERNNVKPLLVMEAILV
VVFTIEYFVRLWSAGSIGKYRGCLGRLRFARKPICVIDLMVVSASVVILLVGRNGNVFAA
SAIRGIRFLQILRMLHVDRQGGTWRLLGSVVYIHRQELITTLYIGFLALIFSSYFVYLAE
K--KFRSYADALWWGVTVTTIGYGDHVPITWLGKVIASCFSIFAISFFALPAGILGSGFA
LKVQQKQRQKQFNRQIPAAAALIQATWRCYATSVGTATWRLFCALSRPLSKEDKSQSIP-
---------------------DGMPESYKNVVRATRRLIYFLAKKRFQRSRKPYDVRDVV
EQYSQGHANVMMRIKELQRRLDLTLGKPSSFTDCQFTTAGGRLLRLEKWTETTDRKLDAI
FKLLEKLNEK-

>Frog_Scaf496_Kcnq3_(ENSXETG00000023036)
-------------------------FLIVLGCLILAILTTFKEYEDASGDWLLLLETFAL
VIFGVEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLGKYWSQTAALIVYTVKQGS-LAP
PQLPTTR-----DMGNNDTTGGTSFILSGLYYSGSQELITAWYIGFLTLILSSFLVYLVE
KEEEFETYADALWWGITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLA
LKVQEQHRQKHFEKRRKPAAELIQSAWRFYATNLSRATWRYY-----GSRDSTFLL---S
SSTHPSGLLLNNPLQLYIIFREDLIPTIKAAIHASRILQFLLHKKRFKETLRPYDVKDVI
EQYSAGHLDMLSRIKYLQTRIDMVFAPGPLSTPKHKKSMMGKFVKVERQVQDMEKKLDFL
VDMHMQHMDQL

>Mouse_Kcnq3_Chr15(ENSG00000184156)
-------------------------FLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAI
FIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGN-VLA
TSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVE
KKEEFETYADALWWGITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLA
LKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRATWRFYLDRVRGSNTKGKLF---S
PSKEPKPVGLNNKERFRTAFREDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVI
EQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSMMGKFVKVERQVHDMGKKLDFL
VDMHMQHMERL

>Chicken_Kcnq3_Chr2(ENSGALG00000016246)
-------------------------FLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAI
FIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGN-VLA
TSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVE
KKEEFETYADALWWGITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLA
LKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRATWRFYKNKARGTNTKGKLF---S
PSKEPKNVVLNNKERFRTAFREDMIPTFKTAIRAVRILQFRLYKKKFKETLRPYDVKDVI
EQYSAGHLDMLSRIKYLQARVDMIFTPGPPSTPKHKKSMMGKFVKVERQVNDMGKKLDFL
VDMHMHHMEQL

>Stickleback_Kcnq3_Scaffold135(ENSGACG00000015812) 
RRIQNLLYDALERPRGWALLYHAFVFLIVLGCLILAILTTFREHEKVSAHWLVILETFAI
FIFGAEFGLRVWAAGCCCRYKGWRGEAQ-VRKLLCILGKHVSNVG---------------
--------------------------IGSSLKEHSR--VNAACRG---------------
-TEVTEVTVSHLQ--ITLTTIGYGDKTPKTWAGRLLAGTFALIGVSFFALPAGILGSGLA
LKVQEQHRQKHFEKRRHPAAGLIQSAWRYYSTNPIRATWRFYLERVRG-----------S
PSKEPKPAGFSNRERFRTAFREEMIPTLKLVIRAVRIMQFLLNKKRFKETLRPYDVKDVI
EQYSAGHLDMLCRIKYLQTRIDMILAPGPLLTPKQKKSMMGRFVRVERQVEDMEKKLDFL
VDMHIQHSEHL

>Stickleback_Kcnq2_GroupXVII(ENSGACG00000003203)
RRLQNFLYNVLERPRGWAFIYHAYVFVLVFSCLVMSVFSTIREYEKSSEDALYILEVVTI
VVFGVEYIVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASISVLAAGTQGNVFAT
SAIRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLCLILASFLVYLAE
KNEQFETYADALWWGITLTTIGYGDKFPITWNGRLLAAAFTLIGVSFFALPAGILGSGFA
LKVQEQHRQKHFEKRRNPAAGLIQAAWRVYATNLSRSTWDYYKERVFPRGSVTKGKGSPH
SSSTPRGF-LGTRMS------QDLTPGLKVTIRAICIMRFMVSKRKFKESLRPYDVMDVI
EQYSAGHLDMLARIKNLQSRVDQIVGRGTPTA-----SMMGRLGKVEKQVHSMERKLDFL
VNIYIQ--RMG

>Mouse_Kcnq2_Chr2(ENSMUSG00000016346)
RKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTI
VVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFAT
SALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAE
KNDHFDTYADALWWGITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA
LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRSTWQYYKDRVFPRGMAAKGKGSPS
PSKVPKSWSFGDRSRTRQAFREDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVI
EQYSAGHLDMLSRIKSLQSRIDMIVGPPPPSTPRHKKSMMGRLGKVEKQVLSMEKKLDFL
VSIYTQ--RMG

>Human_Kcnq2_Chr20(ENSG00000075043)
RKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTI
VVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFAT
SALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAE
KNDHFDTYADALWWGITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA
LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRSTWQYYKDRVFPRGVAAKGKGSPS
PSKVPKSWSFGDRSRARQAFREDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVI
EQYSAGHLDMLSRIKSLQSRIDMIVGPPPPSTPRHKKSMMGRLGKVEKQVLSMEKKLDFL
VNIYMQ--RMG

>Chicken_Kcnq2_Chr20(ENSGALG00000005822)
RKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIDEYQNSSEGALYILEIVTI
VVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFAT
SALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLCLILASFLVYLAE
KNEHFDTYADALWWGITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA
LKVQEQHRQKHFEKRRNPAAGLIQAAWRFYATNLSRSTWQYYKDRVFPRGAGTKGKGSPS
PSKVPKSWSFGDRSRARQAFREDLTPGLKVSIRAVCIMRFLVSKRKFKESLRPYDVMDVI
EQYSAGHLDMLSRIKNLQSRVDQIVGRGSSMT-----SMMGRLGKVEKQVQSMEKKLDFL
VNIYMQ--RMG

>Human_Kcnq5_Chr6(ENSG00000185760)
RRVQNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMI
VVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFAT
SALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVE
KNKEFSTYADALWWGITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA
LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSATWKPHKERVRGQSIKSRQASVGS
PTKVQKSWSFNDRTRFRPSLREDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVI
EQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSRSMLGRVVKVEKQVQSIESKLDCL
LDIYQQVLRKG

>Chicken_Kcnq5_Chr3(ENSGALG00000015932)
-----------------------FSFLLVFGCLILSVFSTIPEHTKLASGCLFILEFVMI
VVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDIIVLIASIAVVSAKTQGNIFAT
SALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVE
KNNQFSTYADALWWGITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA
LKVQEQHRQKHFEKRRNPAASLIQCVWRSYAADEKSATWKPHKERVRGQSIKNRQSSVGS
PTKVQKSWSFNDRTRFRPSLREDLTPALKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVI
EQYSAGHLDMLCRIKSLQSRVDQILGKGQITADKRSRSMLGRVVKVEKQVQSIESKLDCL
LDIYQQVLRKG

>Stickleback_kcnq5_group IX(ENSGACG00000018097)
------LYPLLE-------------FVLVFSCLVLSVFSTIPAHQDFSSYCLLILEFVMI
VVFGLEYIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDIIVLIASVAVVSAGSQGNIFAT
SVLRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLVLIFSSFLVYLVE
NNKDFATYADALWWGITLTTIGYGDKTPKTWTGRMLSAGFALLGISFFALPAGILGSGFA
LKVQEQHRQKHFEKRRNPAAYLIQAAWRCYSTDSTRATWRPYKERVRGQSIKNRQTSSVS
PAKVQKSWSFNDRTRFRPSLRQDLLPSVKSVIRALRIMKFHVAKKKFKETLRPYDVKDVI
EQYSAGHLDMLCRIKSLQTRVDQILGRGQIPLDKKIRSMFGRVCKVERQVQSIESKLDSL
LDIYRQVLRKG

>Frog_Kcnq4_Scaffold377(NM_001079456)  
RRLQNYLYNVLERPRGWAFIYHAFIFFLVFSCLVLSVFSTIPEYHHLANKGLFILEFVMI
VVFGMEYVIRIWSAGCCCRYRGWKGRLRFARKPFCVIDFIVLVASLAVIAAGTQGNIFAT
SALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAE
KNKEFSTYADSLWWGITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFA
LKVQEQHRQKHFEKRRTPAANLIQAAWRLYSTDVSRATWYYYKDRMRKQTTRSKQYLAPS
PTKVQKSWSFNDRTRFRASLREDVMPTIKTLIRAFRILKFLVAKRKFKETLRPYDVKDVI
EQYSAGHLDMLGRIKSLQGRVDQIIGRGPVPVEKKPRSMMGRVVKVERQVQSIEDKLDIL
LGFYSQCIRKG

>Chicken_Kcnq4_Chr 23(DQ346738)    
-RLQNCLYNVLERPRGWAFVYHAFIFLLVFSCLVLSVFSTIQEHQKLANQCLFILEFVMI
VVFGMEYVVRVWAAGCCCRYRGWRGRLRFARKPFCVIDFIVFIASVAVIAAGTQGNIFAT
SALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAE
KNGEFATYADSLWWGVTLTTIGYGDKTPQTWLGRMLAAGFALLGISFFALPAGILGSGFA
LKVQEQHRQKHFEKRRTPAANLIQAAWRLYSTDASRATWCYYKERIRRLGSRGRLHLGPS
PSKVHKSWSFNDRTRFRASLREDIMPAVKTLIRAVRILKFLVAKRKFKETLRPYDVKDVI
EQYSAGHLDMLGRIKSLQTRVDQIVGRGGPAADKKIRSMMGRVVKVERQVQSIEHKLDLL
LGLYSQCLRKG

>Mouse_Kcnq4_Chr4(ENSMUSG00000028631)
RRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMI
VVFGLEYIIRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFAT
SALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAE
KNSDFSSYADSLWWGITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFA
LKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDTSRATWYYYKDRIRKRTGPSKQHLAPS
PSKVQKSWSFNDRTRFRASLRDDVMPAVKTVIRSVRILKFLVAKRKFKETLRPYDVKDVI
EQYSAGHLDMLGRIKSLQARVDQIVGRGPGDRKTREKSMMGRVVKVEKQVQSIEHKLDLL
LGFYSRCLRSG

>Human_Kcnq4_Chr1(ENSG00000117013)
RRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMI
VVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFAT
SALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAE
KNSDFSSYADSLWWGITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFA
LKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRATWYYYKDRIRRRTGPSKQHLAPS
PTKVQKSWSFNDRTRFRASLRDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVI
EQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKSMMGRVVKVEKQVQSIEHKLDLL
LGFYSRCLRSG

>Stick_Kcnq4_GroupX(ENSGACG00000004872)
RKLQNCLYNVLERPRGWAFIYHAFIFLLVFSCLVLSVFSTIPDHQRFANQGLFILEFVMI
VVFGLEYFIRIWAAGCCCRYRGWQGRLRFARKPFCVIDFIVFVASLAVIAAGTQGNIFAT
SALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAE
KNSDFNTYADSLWWGITLTTIGYGDKTPRTWQGRLLAAGFALLGVSFFCTPQGILGSGFA
LKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDAKHATWYFYRDRIRSQTIRSKGSPLPS
PGKVQKSWSFNDRTRFRTSLREEVIPAVKTLIRAVRILKFLVAKRKFKETLRPYDVKDVI
EQYSAGHLDMLGRIKSLQMRVDQIIGRGAVQPDKKARSMMGRVVKVEKQVQSIENKLDLL
LSFYSQCLKKG