{"text_format":"3","workbook":"xls","n_sheets":2,"sheets":["Table.S2A","Table.S2B"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Table.S2A","index":0,"n_rows":35,"n_cols":3,"rows_kept":35,"flags":["formulas_cached_only"]}
["Type","ID","Local European ancestral inference"]
["Phase I","CYP1A1",0.2459]
["Phase I","CYP1A2",0.2459]
["Phase I","CYP2A6",0.2459]
["Phase I","CYP2B6",0.2541]
["Phase I","CYP2C19",0.2541]
["Phase I","CYP2C8",0.2541]
["Phase I","CYP2C9",0.2541]
["Phase I","CYP2D6",0.3197]
["Phase I","CYP2E1",0.2957]
["Phase I","CYP3A4",0.2213]
["Phase I","CYP3A5",0.2213]
["Phase I","DPYD",0.2787]
[]
["Phase II","GSTM1",0.2431]
["Phase II","GSTP1",0.25]
["Phase II","GSTT1",0.2458]
["Phase II","NAT1",0.2984]
["Phase II","NAT2",0.3]
["Phase II","SULT1A1",0.2196]
["Phase II","TPMT",0.25]
["Phase II","UGT1A1",0.3338]
["Phase II","UGT2B15",0.1657]
["Phase II","UGT2B17",0.175]
["Phase II","UGT2B7",0.1583]
[]
["Transporter","ABCB1",0.1885]
["Transporter","ABCC2",0.2705]
["Transporter","ABCG2",0.1638]
["Transporter","SLC15A2",0.2667]
["Transporter","SLC22A1",0.2963]
["Transporter","SLC22A2",0.2951]
["Transporter","SLC22A6",0.2417]
["Transporter","SLCO1B1",0.2648]
["Transporter","SLCO1B3",0.2667]

{"sheet":"Table.S2B","index":1,"n_rows":256,"n_cols":3,"rows_kept":256,"flags":["formulas_cached_only"]}
["Type","Genes","Local European ancestral inference"]
["Phase I","ADH1A",0.1667]
["Phase I","ADH1B",0.1667]
["Phase I","ADH1C",0.1656]
["Phase I","ADH4",0.1699]
["Phase I","ADH5",0.1721]
["Phase I","ADH6",0.1667]
["Phase I","ADH7",0.161]
["Phase I","ADHFE1",0.2623]
["Phase I","ALDH1A1",0.3115]
["Phase I","ALDH1A2",0.2083]
["Phase I","ALDH1A3",0.2555]
["Phase I","ALDH1B1",0.272]
["Phase I","ALDH2",0.25]
["Phase I","ALDH3A1",0.2459]
["Phase I","ALDH3A2",0.2459]
["Phase I","ALDH3B1",0.2303]
["Phase I","ALDH3B2",0.25]
["Phase I","ALDH4A1",0.2351]
["Phase I","ALDH5A1",0.2295]
["Phase I","ALDH6A1",0.2377]
["Phase I","ALDH7A1",0.2601]
["Phase I","ALDH8A1",0.2476]
["Phase I","ALDH9A1",0.2541]
["Phase I","AOX1",0.2667]
["Phase I","CBR1",0.2951]
["Phase I","CBR3",0.2889]
["Phase I","CES1",0.2712]
["Phase I","CES2",0.2459]
["Phase I","CYB5R3",0.3197]
["Phase I","CYP11A1",0.2459]
["Phase I","CYP11B1",0.2373]
["Phase I","CYP11B2",0.2373]
["Phase I","CYP17A1",0.2417]
["Phase I","CYP19A1",0.2091]
["Phase I","CYP1B1",0.2417]
["Phase I","CYP20A1",0.2705]
["Phase I","CYP21A2",0.295]
["Phase I","CYP24A1",0.2131]
["Phase I","CYP26A1",0.2417]
["Phase I","CYP26C1",0.2417]
["Phase I","CYP27A1",0.3185]
["Phase I","CYP27B1",0.2881]
["Phase I","CYP2A13",0.2541]
["Phase I","CYP2A7",0.2417]
["Phase I","CYP2C18",0.2541]
["Phase I","CYP2F1",0.2541]
["Phase I","CYP2J2",0.3]
["Phase I","CYP2R1",0.3167]
["Phase I","CYP2S1",0.2541]
["Phase I","CYP39A1",0.2049]
["Phase I","CYP3A43",0.2213]
["Phase I","CYP3A7",0.2213]
["Phase I","CYP46A1",0.2061]
["Phase I","CYP4A11",0.2787]
["Phase I","CYP4B1",0.2787]
["Phase I","CYP4F11",0.2213]
["Phase I","CYP4F12",0.2182]
["Phase I","CYP4F2",0.2213]
["Phase I","CYP4F3",0.2333]
["Phase I","CYP4F8",0.2333]
["Phase I","CYP4Z1",0.2787]
["Phase I","CYP51A1",0.1949]
["Phase I","CYP7A1",0.2541]
["Phase I","CYP7B1",0.2729]
["Phase I","CYP8B1",0.2459]
["Phase I","DDO",0.2295]
["Phase I","DHRS1",0.2333]
["Phase I","DHRS12",0.1667]
["Phase I","DHRS13",0.2459]
["Phase I","DHRS2",0.2377]
["Phase I","DHRS3",0.2417]
["Phase I","DHRS4",0.2541]
["Phase I","DHRS4L2",0.2541]
["Phase I","DHRS7",0.1842]
["Phase I","DHRS7B",0.25]
["Phase I","DHRS7C",0.2104]
["Phase I","DHRS9",0.2006]
["Phase I","DPEP1",0.3033]
["Phase I","EPHX1",0.2667]
["Phase I","EPHX2",0.2623]
["Phase I","FMO1",0.2583]
["Phase I","FMO2",0.2583]
["Phase I","FMO3",0.2583]
["Phase I","FMO4",0.2583]
["Phase I","FMO5",0.1557]
["Phase I","GPX1",0.2583]
["Phase I","GPX2",0.2131]
["Phase I","GPX3",0.1949]
["Phase I","GPX4",0.1843]
["Phase I","GPX5",0.219]
["Phase I","GPX6",0.25]
["Phase I","GPX7",0.283]
["Phase I","GSR",0.2284]
["Phase I","GSS",0.2131]
["Phase I","HAGH",0.2083]
["Phase I","HSD11B1",0.2541]
["Phase I","HSD17B11",0.1639]
["Phase I","HSD17B14",0.2303]
["Phase I","METAP1",0.1721]
["Phase I","NOS1",0.2459]
["Phase I","NOS2A",0.193]
["Phase I","NOS3",0.2586]
["Phase I","PDE3A",0.283]
["Phase I","PDE3B",0.3167]
["Phase I","PLGLB1",0.225]
["Phase I","PON1",0.1907]
["Phase I","PON2",0.1875]
["Phase I","PON3",0.1897]
["Phase I","SULF1",0.2386]
["Phase I","XDH",0.2869]
[]
["Phase II","CHST1",0.2213]
["Phase II","CHST10",0.1628]
["Phase II","CHST11",0.2434]
["Phase II","CHST12",0.2623]
["Phase II","CHST13",0.2213]
["Phase II","CHST2",0.225]
["Phase II","CHST3",0.2705]
["Phase II","CHST4",0.2458]
["Phase II","CHST5",0.2583]
["Phase II","CHST6",0.2636]
["Phase II","CHST8",0.2295]
["Phase II","CHST9",0.25]
["Phase II","GSTA1",0.2667]
["Phase II","GSTA2",0.2667]
["Phase II","GSTA3",0.2705]
["Phase II","GSTA4",0.2623]
["Phase II","GSTA5",0.2697]
["Phase II","GSTCD",0.2131]
["Phase II","GSTK1",0.3103]
["Phase II","GSTM2",0.2459]
["Phase II","GSTM3",0.2417]
["Phase II","GSTM4",0.2459]
["Phase II","GSTM5",0.2417]
["Phase II","GSTO1",0.2333]
["Phase II","GSTO2",0.2333]
["Phase II","GSTT2",0.2458]
["Phase II","GSTZ1",0.2213]
["Phase II","HNMT",0.2]
["Phase II","MGST1",0.2951]
["Phase II","MGST2",0.2014]
["Phase II","MGST3",0.2541]
["Phase II","NNMT",0.2176]
["Phase II","PNMT",0.2583]
["Phase II","SULT1A2",0.2219]
["Phase II","SULT1A3",0.242]
["Phase II","SULT1B1",0.1639]
["Phase II","SULT1C2",0.1528]
["Phase II","SULT1E1",0.1639]
["Phase II","SULT2A1",0.2295]
["Phase II","SULT2B1",0.2254]
["Phase II","SULT4A1",0.2917]
["Phase II","UGT1A10",0.3394]
["Phase II","UGT1A3",0.3368]
["Phase II","UGT1A4",0.3373]
["Phase II","UGT1A5",0.3373]
["Phase II","UGT1A6",0.3381]
["Phase II","UGT1A7",0.3384]
["Phase II","UGT1A8",0.3396]
["Phase II","UGT1A9",0.3387]
["Phase II","UGT2A1",0.1676]
["Phase II","UGT2B10",0.2011]
["Phase II","UGT2B11",0.1583]
["Phase II","UGT2B28",0.1583]
["Phase II","UGT2B4",0.1638]
["Phase II","UGT8",0.2131]
[]
["Transporter","ABCA1",0.2785]
["Transporter","ABCA4",0.268]
["Transporter","ABCB11",0.2076]
["Transporter","ABCB4",0.1895]
["Transporter","ABCB5",0.2623]
["Transporter","ABCB6",0.3033]
["Transporter","ABCB8",0.2586]
["Transporter","ABCC1",0.2193]
["Transporter","ABCC10",0.2]
["Transporter","ABCC11",0.2537]
["Transporter","ABCC12",0.25]
["Transporter","ABCC3",0.2869]
["Transporter","ABCC4",0.1967]
["Transporter","ABCC5",0.2677]
["Transporter","ABCC6",0.2191]
["Transporter","ABCC8",0.3271]
["Transporter","ABCC9",0.2555]
["Transporter","ABCG1",0.3463]
["Transporter","SLC10A1",0.2333]
["Transporter","SLC10A2",0.2046]
["Transporter","SLC13A1",0.2131]
["Transporter","SLC13A2",0.2459]
["Transporter","SLC13A3",0.1768]
["Transporter","SLC15A1",0.233]
["Transporter","SLC16A1",0.1967]
["Transporter","SLC19A1",0.3162]
["Transporter","SLC22A10",0.2373]
["Transporter","SLC22A11",0.2541]
["Transporter","SLC22A12",0.2541]
["Transporter","SLC22A13",0.2583]
["Transporter","SLC22A14",0.2583]
["Transporter","SLC22A15",0.1721]
["Transporter","SLC22A16",0.2289]
["Transporter","SLC22A17",0.2541]
["Transporter","SLC22A18",0.2705]
["Transporter","SLC22A3",0.2951]
["Transporter","SLC22A4",0.2705]
["Transporter","SLC22A5",0.2705]
["Transporter","SLC22A7",0.2]
["Transporter","SLC22A8",0.2399]
["Transporter","SLC22A9",0.2373]
["Transporter","SLC27A1",0.2407]
["Transporter","SLC28A1",0.2131]
["Transporter","SLC28A2",0.1917]
["Transporter","SLC28A3",0.2866]
["Transporter","SLC29A1",0.1885]
["Transporter","SLC29A2",0.2623]
["Transporter","SLC2A4",0.2083]
["Transporter","SLC2A5",0.2377]
["Transporter","SLC5A6",0.2377]
["Transporter","SLC6A6",0.2145]
["Transporter","SLC7A5",0.2869]
["Transporter","SLC7A7",0.3]
["Transporter","SLC7A8",0.2564]
["Transporter","SLCO1A2",0.2623]
["Transporter","SLCO1C1",0.2747]
["Transporter","SLCO2A1",0.2377]
["Transporter","SLCO2B1",0.2131]
["Transporter","SLCO3A1",0.2751]
["Transporter","SLCO4A1",0.3082]
["Transporter","SLCO4C1",0.2458]
["Transporter","SLCO5A1",0.24]
["Transporter","SLCO6A1",0.2458]
["Transporter","TAP1",0.325]
["Transporter","TAP2",0.325]
[]
["Modifier","AHR",0.2417]
["Modifier","ARNT",0.1557]
["Modifier","ARSA",0.3022]
["Modifier","ATP7B",0.175]
["Modifier","CAT",0.2333]
["Modifier","CDA",0.2377]
["Modifier","CFTR",0.2167]
["Modifier","HNF4A",0.1561]
["Modifier","IAPP",0.2623]
["Modifier","KCNJ11",0.3279]
["Modifier","MAT1A",0.2049]
["Modifier","MPO",0.2417]
["Modifier","NR1I2",0.276]
["Modifier","NR1I3",0.2069]
["Modifier","POR",0.1771]
["Modifier","PPARA",0.2869]
["Modifier","PPARD",0.2541]
["Modifier","PPARG",0.2083]
["Modifier","RXRA",0.2447]
["Modifier","SOD1",0.225]
["Modifier","SOD2",0.2797]
["Modifier","SOD3",0.2417]