>hsa-let-7a-1 MA:6-27;mi:57-77 Normal ugggaUGAGGUAGUAGGUUGUAUAGUUuuagggucacacccaccacugggagauaaCUAUACAAUCUACUGUCUUUCcua -----UGAGGUAGUAGGUUGUAU--------------------------------------------------------- 908 0,-4 -----UGAGGUAGUAGGUUGUAUu-------------------------------------------------------- 23 0,-4 -----UGAGGUAGUAGGUUGUAUA-------------------------------------------------------- 333 0,-3 -----UGAGGUAGUAGGUUGUAUAa------------------------------------------------------- 178 0,-3 -----UGAGGUAGUAGGUUGUAUAaa------------------------------------------------------ 59 0,-3 -----UGAGGUAGUAGGUUGUAUAau------------------------------------------------------ 17 0,-3 -----UGAGGUAGUAGGUUGUAUAc------------------------------------------------------- 2 0,-3 -----UGAGGUAGUAGGUUGUAUAu------------------------------------------------------- 21 0,-3 -----UGAGGUAGUAGGUUGUAUAuu------------------------------------------------------ 42 0,-3 -----UGAGGUAGUAGGUUGUAUAG------------------------------------------------------- 2339 0,-2 -----UGAGGUAGUAGGUUGUAUAGa------------------------------------------------------ 584 0,-2 -----UGAGGUAGUAGGUUGUAUAGaa----------------------------------------------------- 151 0,-2 -----UGAGGUAGUAGGUUGUAUAGau----------------------------------------------------- 29 0,-2 -----UGAGGUAGUAGGUUGUAUAGc------------------------------------------------------ 18 0,-2 -----UGAGGUAGUAGGUUGUAUAGg------------------------------------------------------ 15 0,-2 -----UGAGGUAGUAGGUUGUAUAGU------------------------------------------------------ 17074 0,-1 -----UGAGGUAGUAGGUUGUAUAGUa----------------------------------------------------- 708 0,-1 -----UGAGGUAGUAGGUUGUAUAGUaa---------------------------------------------------- 288 0,-1 -----UGAGGUAGUAGGUUGUAUAGUau---------------------------------------------------- 79 0,-1 -----UGAGGUAGUAGGUUGUAUAGUc----------------------------------------------------- 69 0,-1 -----UGAGGUAGUAGGUUGUAUAGUg----------------------------------------------------- 29 0,-1 -----UGAGGUAGUAGGUUGUAUAGUU----------------------------------------------------- 39963 0,0 -----UGAGGUAGUAGGUUGUAUAGUUa---------------------------------------------------- 1588 0,0 -----UGAGGUAGUAGGUUGUAUAGUUaa--------------------------------------------------- 67 0,0 -----UGAGGUAGUAGGUUGUAUAGUUau--------------------------------------------------- 18 0,0 -----UGAGGUAGUAGGUUGUAUAGUUc---------------------------------------------------- 19 0,0 -----UGAGGUAGUAGGUUGUAUAGUUg---------------------------------------------------- 157 0,0 -----UGAGGUAGUAGGUUGUAUAGUUU---------------------------------------------------- 1634 0,1 -----UGAGGUAGUAGGUUGUAUAGUUUU--------------------------------------------------- 8 0,2 ------GAGGUAGUAGGUUGUAUA-------------------------------------------------------- 5 1,-3 ------GAGGUAGUAGGUUGUAUAuu------------------------------------------------------ 2 1,-3 ------GAGGUAGUAGGUUGUAUAG------------------------------------------------------- 54 1,-2 ------GAGGUAGUAGGUUGUAUAGa------------------------------------------------------ 14 1,-2 ------GAGGUAGUAGGUUGUAUAGU------------------------------------------------------ 420 1,-1 ------GAGGUAGUAGGUUGUAUAGUa----------------------------------------------------- 14 1,-1 ------GAGGUAGUAGGUUGUAUAGUaa---------------------------------------------------- 2 1,-1 ------GAGGUAGUAGGUUGUAUAGUU----------------------------------------------------- 964 1,0 ------GAGGUAGUAGGUUGUAUAGUUa---------------------------------------------------- 39 1,0 ------GAGGUAGUAGGUUGUAUAGUUg---------------------------------------------------- 10 1,0 ------GAGGUAGUAGGUUGUAUAGUUU---------------------------------------------------- 28 1,1 -------AGGUAGUAGGUUGUAUAGU------------------------------------------------------ 5 2,-1 -------AGGUAGUAGGUUGUAUAGUU----------------------------------------------------- 26 2,0 --------------------------------------------------------CUAUACAAUCUACUGUCUU----- 6 0,-2 --------------------------------------------------------CUAUACAAUCUACUGUCUUU---- 146 0,-1 --------------------------------------------------------CUAUACAAUCUACUGUCUUUC--- 61 0,0 --------------------------------------------------------CUAUACAAUCUACUGUCUUUCu-- 82 0,0 --------------------------------------------------------CUAUACAAUCUACUGUCUUUCC-- 33 0,1 --------------------------------------------------------CUAUACAAUCUACUGUCUUUCCa- 7 0,1 ---------------------------------------------------------UAUACAAUCUACUGUCUUU---- 4 1,-1 ---------------------------------------------------------UAUACAAUCUACUGUCUUUC--- 5 1,0 ----------------------------------------------------------AUACAAUCUACUGUCUUU---- 2 2,-1 >hsa-let-7a-2 MA:5-26;mi:50-71 Normal agguUGAGGUAGUAGGUUGUAUAGUUuagaauuacaucaagggagauaaCUGUACAGCCUCCUAGCUUUCCu ----UGAGGUAGUAGGUUGUAU-------------------------------------------------- 908 0,-4 ----UGAGGUAGUAGGUUGUAUu------------------------------------------------- 23 0,-4 ----UGAGGUAGUAGGUUGUAUA------------------------------------------------- 333 0,-3 ----UGAGGUAGUAGGUUGUAUAa------------------------------------------------ 178 0,-3 ----UGAGGUAGUAGGUUGUAUAaa----------------------------------------------- 59 0,-3 ----UGAGGUAGUAGGUUGUAUAau----------------------------------------------- 17 0,-3 ----UGAGGUAGUAGGUUGUAUAc------------------------------------------------ 2 0,-3 ----UGAGGUAGUAGGUUGUAUAu------------------------------------------------ 21 0,-3 ----UGAGGUAGUAGGUUGUAUAuu----------------------------------------------- 42 0,-3 ----UGAGGUAGUAGGUUGUAUAG------------------------------------------------ 2339 0,-2 ----UGAGGUAGUAGGUUGUAUAGa----------------------------------------------- 584 0,-2 ----UGAGGUAGUAGGUUGUAUAGaa---------------------------------------------- 151 0,-2 ----UGAGGUAGUAGGUUGUAUAGau---------------------------------------------- 29 0,-2 ----UGAGGUAGUAGGUUGUAUAGc----------------------------------------------- 18 0,-2 ----UGAGGUAGUAGGUUGUAUAGg----------------------------------------------- 15 0,-2 ----UGAGGUAGUAGGUUGUAUAGU----------------------------------------------- 17074 0,-1 ----UGAGGUAGUAGGUUGUAUAGUa---------------------------------------------- 708 0,-1 ----UGAGGUAGUAGGUUGUAUAGUaa--------------------------------------------- 288 0,-1 ----UGAGGUAGUAGGUUGUAUAGUau--------------------------------------------- 79 0,-1 ----UGAGGUAGUAGGUUGUAUAGUc---------------------------------------------- 69 0,-1 ----UGAGGUAGUAGGUUGUAUAGUg---------------------------------------------- 29 0,-1 ----UGAGGUAGUAGGUUGUAUAGUU---------------------------------------------- 39963 0,0 ----UGAGGUAGUAGGUUGUAUAGUUa--------------------------------------------- 1588 0,0 ----UGAGGUAGUAGGUUGUAUAGUUaa-------------------------------------------- 67 0,0 ----UGAGGUAGUAGGUUGUAUAGUUau-------------------------------------------- 18 0,0 ----UGAGGUAGUAGGUUGUAUAGUUc--------------------------------------------- 19 0,0 ----UGAGGUAGUAGGUUGUAUAGUUg--------------------------------------------- 157 0,0 ----UGAGGUAGUAGGUUGUAUAGUUU--------------------------------------------- 1634 0,1 ----UGAGGUAGUAGGUUGUAUAGUUUA-------------------------------------------- 2 0,2 -----GAGGUAGUAGGUUGUAUA------------------------------------------------- 5 1,-3 -----GAGGUAGUAGGUUGUAUAuu----------------------------------------------- 2 1,-3 -----GAGGUAGUAGGUUGUAUAG------------------------------------------------ 54 1,-2 -----GAGGUAGUAGGUUGUAUAGa----------------------------------------------- 14 1,-2 -----GAGGUAGUAGGUUGUAUAGU----------------------------------------------- 420 1,-1 -----GAGGUAGUAGGUUGUAUAGUa---------------------------------------------- 14 1,-1 -----GAGGUAGUAGGUUGUAUAGUaa--------------------------------------------- 2 1,-1 -----GAGGUAGUAGGUUGUAUAGUU---------------------------------------------- 964 1,0 -----GAGGUAGUAGGUUGUAUAGUUa--------------------------------------------- 39 1,0 -----GAGGUAGUAGGUUGUAUAGUUg--------------------------------------------- 10 1,0 -----GAGGUAGUAGGUUGUAUAGUUU--------------------------------------------- 28 1,1 ------AGGUAGUAGGUUGUAUAGU----------------------------------------------- 5 2,-1 ------AGGUAGUAGGUUGUAUAGUU---------------------------------------------- 26 2,0 -------------------------------------------------CUGUACAGCCUCCUAGCUUUC-- 2 0,-1 -------------------------------------------------CUGUACAGCCUCCUAGCUUUCC- 2 0,0 >hsa-let-7a-3 MA:4-25;mi:52-72 Normal gggUGAGGUAGUAGGUUGUAUAGUUuggggcucugcccugcuaugggauaaCUAUACAAUCUACUGUCUUUCcu --GUGAGGUAGUAGGUUGUAU----------------------------------------------------- 2 -1,-4 --GUGAGGUAGUAGGUUGUAUAG--------------------------------------------------- 5 -1,-2 --GUGAGGUAGUAGGUUGUAUAGU-------------------------------------------------- 61 -1,-1 --GUGAGGUAGUAGGUUGUAUAGUa------------------------------------------------- 2 -1,-1 --GUGAGGUAGUAGGUUGUAUAGUU------------------------------------------------- 43 -1,0 ---UGAGGUAGUAGGUUGUAU----------------------------------------------------- 908 0,-4 ---UGAGGUAGUAGGUUGUAUu---------------------------------------------------- 23 0,-4 ---UGAGGUAGUAGGUUGUAUA---------------------------------------------------- 333 0,-3 ---UGAGGUAGUAGGUUGUAUAa--------------------------------------------------- 178 0,-3 ---UGAGGUAGUAGGUUGUAUAaa-------------------------------------------------- 59 0,-3 ---UGAGGUAGUAGGUUGUAUAau-------------------------------------------------- 17 0,-3 ---UGAGGUAGUAGGUUGUAUAc--------------------------------------------------- 2 0,-3 ---UGAGGUAGUAGGUUGUAUAu--------------------------------------------------- 21 0,-3 ---UGAGGUAGUAGGUUGUAUAuu-------------------------------------------------- 42 0,-3 ---UGAGGUAGUAGGUUGUAUAG--------------------------------------------------- 2339 0,-2 ---UGAGGUAGUAGGUUGUAUAGa-------------------------------------------------- 584 0,-2 ---UGAGGUAGUAGGUUGUAUAGaa------------------------------------------------- 151 0,-2 ---UGAGGUAGUAGGUUGUAUAGau------------------------------------------------- 29 0,-2 ---UGAGGUAGUAGGUUGUAUAGc-------------------------------------------------- 18 0,-2 ---UGAGGUAGUAGGUUGUAUAGg-------------------------------------------------- 15 0,-2 ---UGAGGUAGUAGGUUGUAUAGU-------------------------------------------------- 17074 0,-1 ---UGAGGUAGUAGGUUGUAUAGUa------------------------------------------------- 708 0,-1 ---UGAGGUAGUAGGUUGUAUAGUaa------------------------------------------------ 288 0,-1 ---UGAGGUAGUAGGUUGUAUAGUau------------------------------------------------ 79 0,-1 ---UGAGGUAGUAGGUUGUAUAGUc------------------------------------------------- 69 0,-1 ---UGAGGUAGUAGGUUGUAUAGUg------------------------------------------------- 29 0,-1 ---UGAGGUAGUAGGUUGUAUAGUU------------------------------------------------- 39963 0,0 ---UGAGGUAGUAGGUUGUAUAGUUa------------------------------------------------ 1588 0,0 ---UGAGGUAGUAGGUUGUAUAGUUaa----------------------------------------------- 67 0,0 ---UGAGGUAGUAGGUUGUAUAGUUau----------------------------------------------- 18 0,0 ---UGAGGUAGUAGGUUGUAUAGUUc------------------------------------------------ 19 0,0 ---UGAGGUAGUAGGUUGUAUAGUUg------------------------------------------------ 157 0,0 ---UGAGGUAGUAGGUUGUAUAGUUU------------------------------------------------ 1634 0,1 ----GAGGUAGUAGGUUGUAUA---------------------------------------------------- 5 1,-3 ----GAGGUAGUAGGUUGUAUAuu-------------------------------------------------- 2 1,-3 ----GAGGUAGUAGGUUGUAUAG--------------------------------------------------- 54 1,-2 ----GAGGUAGUAGGUUGUAUAGa-------------------------------------------------- 14 1,-2 ----GAGGUAGUAGGUUGUAUAGU-------------------------------------------------- 420 1,-1 ----GAGGUAGUAGGUUGUAUAGUa------------------------------------------------- 14 1,-1 ----GAGGUAGUAGGUUGUAUAGUaa------------------------------------------------ 2 1,-1 ----GAGGUAGUAGGUUGUAUAGUU------------------------------------------------- 964 1,0 ----GAGGUAGUAGGUUGUAUAGUUa------------------------------------------------ 39 1,0 ----GAGGUAGUAGGUUGUAUAGUUg------------------------------------------------ 10 1,0 ----GAGGUAGUAGGUUGUAUAGUUU------------------------------------------------ 28 1,1 -----AGGUAGUAGGUUGUAUAGU-------------------------------------------------- 5 2,-1 -----AGGUAGUAGGUUGUAUAGUU------------------------------------------------- 26 2,0 ---------------------------------------------------CUAUACAAUCUACUGUCUU---- 6 0,-2 ---------------------------------------------------CUAUACAAUCUACUGUCUUU--- 146 0,-1 ---------------------------------------------------CUAUACAAUCUACUGUCUUUC-- 61 0,0 ---------------------------------------------------CUAUACAAUCUACUGUCUUUCu- 82 0,0 ---------------------------------------------------CUAUACAAUCUACUGUCUUUCC- 33 0,1 ---------------------------------------------------CUAUACAAUCUACUGUCUUUCCa 7 0,1 ----------------------------------------------------UAUACAAUCUACUGUCUUU--- 4 1,-1 ----------------------------------------------------UAUACAAUCUACUGUCUUUC-- 5 1,0 -----------------------------------------------------AUACAAUCUACUGUCUUU--- 2 2,-1 >hsa-let-7b MA:6-27;mi:60-81 Normal cggggUGAGGUAGUAGGUUGUGUGGUUucagggcagugauguugccccucggaagauaaCUAUACAACCUACUGCCUUCCCug ----GUGAGGUAGUAGGUUGUGUGGUU-------------------------------------------------------- 2 -1,0 -----UGAGGUAGUAGGUUGUGU------------------------------------------------------------ 985 0,-4 -----UGAGGUAGUAGGUUGUGUa----------------------------------------------------------- 5 0,-4 -----UGAGGUAGUAGGUUGUGUaa---------------------------------------------------------- 64 0,-4 -----UGAGGUAGUAGGUUGUGUau---------------------------------------------------------- 5 0,-4 -----UGAGGUAGUAGGUUGUGUu----------------------------------------------------------- 7 0,-4 -----UGAGGUAGUAGGUUGUGUG----------------------------------------------------------- 668 0,-3 -----UGAGGUAGUAGGUUGUGUGa---------------------------------------------------------- 778 0,-3 -----UGAGGUAGUAGGUUGUGUGaa--------------------------------------------------------- 165 0,-3 -----UGAGGUAGUAGGUUGUGUGau--------------------------------------------------------- 34 0,-3 -----UGAGGUAGUAGGUUGUGUGc---------------------------------------------------------- 5 0,-3 -----UGAGGUAGUAGGUUGUGUGu---------------------------------------------------------- 204 0,-3 -----UGAGGUAGUAGGUUGUGUGuu--------------------------------------------------------- 39 0,-3 -----UGAGGUAGUAGGUUGUGUGG---------------------------------------------------------- 4164 0,-2 -----UGAGGUAGUAGGUUGUGUGGa--------------------------------------------------------- 673 0,-2 -----UGAGGUAGUAGGUUGUGUGGaa-------------------------------------------------------- 574 0,-2 -----UGAGGUAGUAGGUUGUGUGGau-------------------------------------------------------- 66 0,-2 -----UGAGGUAGUAGGUUGUGUGGc--------------------------------------------------------- 13 0,-2 -----UGAGGUAGUAGGUUGUGUGGg--------------------------------------------------------- 2 0,-2 -----UGAGGUAGUAGGUUGUGUGGU--------------------------------------------------------- 12453 0,-1 -----UGAGGUAGUAGGUUGUGUGGUa-------------------------------------------------------- 1694 0,-1 -----UGAGGUAGUAGGUUGUGUGGUaa------------------------------------------------------- 1573 0,-1 -----UGAGGUAGUAGGUUGUGUGGUau------------------------------------------------------- 1646 0,-1 -----UGAGGUAGUAGGUUGUGUGGUc-------------------------------------------------------- 74 0,-1 -----UGAGGUAGUAGGUUGUGUGGUg-------------------------------------------------------- 53 0,-1 -----UGAGGUAGUAGGUUGUGUGGUU-------------------------------------------------------- 39775 0,0 -----UGAGGUAGUAGGUUGUGUGGUUa------------------------------------------------------- 3465 0,0 -----UGAGGUAGUAGGUUGUGUGGUUaa------------------------------------------------------ 585 0,0 -----UGAGGUAGUAGGUUGUGUGGUUau------------------------------------------------------ 883 0,0 -----UGAGGUAGUAGGUUGUGUGGUUc------------------------------------------------------- 67 0,0 -----UGAGGUAGUAGGUUGUGUGGUUg------------------------------------------------------- 315 0,0 -----UGAGGUAGUAGGUUGUGUGGUUU------------------------------------------------------- 15795 0,1 -----UGAGGUAGUAGGUUGUGUGGUUUa------------------------------------------------------ 140 0,1 -----UGAGGUAGUAGGUUGUGUGGUUUaa----------------------------------------------------- 23 0,1 -----UGAGGUAGUAGGUUGUGUGGUUUau----------------------------------------------------- 26 0,1 -----UGAGGUAGUAGGUUGUGUGGUUUg------------------------------------------------------ 13 0,1 -----UGAGGUAGUAGGUUGUGUGGUUUu------------------------------------------------------ 1416 0,1 -----UGAGGUAGUAGGUUGUGUGGUUUuu----------------------------------------------------- 99 0,1 -----UGAGGUAGUAGGUUGUGUGGUUUC------------------------------------------------------ 11 0,2 ------GAGGUAGUAGGUUGUGUG----------------------------------------------------------- 9 1,-3 ------GAGGUAGUAGGUUGUGUGa---------------------------------------------------------- 7 1,-3 ------GAGGUAGUAGGUUGUGUGau--------------------------------------------------------- 2 1,-3 ------GAGGUAGUAGGUUGUGUGuu--------------------------------------------------------- 2 1,-3 ------GAGGUAGUAGGUUGUGUGG---------------------------------------------------------- 106 1,-2 ------GAGGUAGUAGGUUGUGUGGa--------------------------------------------------------- 4 1,-2 ------GAGGUAGUAGGUUGUGUGGaa-------------------------------------------------------- 3 1,-2 ------GAGGUAGUAGGUUGUGUGGU--------------------------------------------------------- 301 1,-1 ------GAGGUAGUAGGUUGUGUGGUa-------------------------------------------------------- 55 1,-1 ------GAGGUAGUAGGUUGUGUGGUaa------------------------------------------------------- 30 1,-1 ------GAGGUAGUAGGUUGUGUGGUau------------------------------------------------------- 40 1,-1 ------GAGGUAGUAGGUUGUGUGGUc-------------------------------------------------------- 3 1,-1 ------GAGGUAGUAGGUUGUGUGGUU-------------------------------------------------------- 1042 1,0 ------GAGGUAGUAGGUUGUGUGGUUa------------------------------------------------------- 95 1,0 ------GAGGUAGUAGGUUGUGUGGUUaa------------------------------------------------------ 17 1,0 ------GAGGUAGUAGGUUGUGUGGUUau------------------------------------------------------ 25 1,0 ------GAGGUAGUAGGUUGUGUGGUUg------------------------------------------------------- 5 1,0 ------GAGGUAGUAGGUUGUGUGGUUU------------------------------------------------------- 369 1,1 ------GAGGUAGUAGGUUGUGUGGUUUa------------------------------------------------------ 2 1,1 ------GAGGUAGUAGGUUGUGUGGUUUu------------------------------------------------------ 42 1,1 ------GAGGUAGUAGGUUGUGUGGUUUuu----------------------------------------------------- 5 1,1 -------AGGUAGUAGGUUGUGUGG---------------------------------------------------------- 3 2,-2 -------AGGUAGUAGGUUGUGUGGU--------------------------------------------------------- 17 2,-1 -------AGGUAGUAGGUUGUGUGGUU-------------------------------------------------------- 41 2,0 -------AGGUAGUAGGUUGUGUGGUUU------------------------------------------------------- 19 2,1 -----------------------------------------------------------CUAUACAACCUACUGCCUUC---- 91 0,-2 -----------------------------------------------------------CUAUACAACCUACUGCCUUCu--- 21 0,-2 -----------------------------------------------------------CUAUACAACCUACUGCCUUCC--- 102 0,-1 -----------------------------------------------------------CUAUACAACCUACUGCCUUCCa-- 4 0,-1 -----------------------------------------------------------CUAUACAACCUACUGCCUUCCu-- 87 0,-1 ------------------------------------------------------------UAUACAACCUACUGCCUUC---- 2 1,-2 ------------------------------------------------------------UAUACAACCUACUGCCUUCu--- 3 1,-2 ------------------------------------------------------------UAUACAACCUACUGCCUUCC--- 2 1,-1 ------------------------------------------------------------UAUACAACCUACUGCCUUCCu-- 7 1,-1 >hsa-let-7c 5pM:11-32 Normal gcauccggguUGAGGUAGUAGGUUGUAUGGUUuagaguuacacccugggaguuaacuguacaaccuucuagcuuuccuuggagc --------GUUGAGGUAGUAGGUUGUAUGGU----------------------------------------------------- 4 -2,-1 ---------UUGAGGUAGUAGGUUGUAUGG------------------------------------------------------ 2 -1,-2 ---------UUGAGGUAGUAGGUUGUAUGGU----------------------------------------------------- 43 -1,-1 ---------UUGAGGUAGUAGGUUGUAUGGUU---------------------------------------------------- 31 -1,0 ----------UGAGGUAGUAGGUUGUAU-------------------------------------------------------- 908 0,-4 ----------UGAGGUAGUAGGUUGUAUu------------------------------------------------------- 23 0,-4 ----------UGAGGUAGUAGGUUGUAUG------------------------------------------------------- 89 0,-3 ----------UGAGGUAGUAGGUUGUAUGa------------------------------------------------------ 42 0,-3 ----------UGAGGUAGUAGGUUGUAUGaa----------------------------------------------------- 8 0,-3 ----------UGAGGUAGUAGGUUGUAUGau----------------------------------------------------- 5 0,-3 ----------UGAGGUAGUAGGUUGUAUGu------------------------------------------------------ 4 0,-3 ----------UGAGGUAGUAGGUUGUAUGuu----------------------------------------------------- 3 0,-3 ----------UGAGGUAGUAGGUUGUAUGG------------------------------------------------------ 329 0,-2 ----------UGAGGUAGUAGGUUGUAUGGa----------------------------------------------------- 74 0,-2 ----------UGAGGUAGUAGGUUGUAUGGaa---------------------------------------------------- 56 0,-2 ----------UGAGGUAGUAGGUUGUAUGGU----------------------------------------------------- 2196 0,-1 ----------UGAGGUAGUAGGUUGUAUGGUa---------------------------------------------------- 537 0,-1 ----------UGAGGUAGUAGGUUGUAUGGUaa--------------------------------------------------- 214 0,-1 ----------UGAGGUAGUAGGUUGUAUGGUau--------------------------------------------------- 82 0,-1 ----------UGAGGUAGUAGGUUGUAUGGUc---------------------------------------------------- 16 0,-1 ----------UGAGGUAGUAGGUUGUAUGGUg---------------------------------------------------- 13 0,-1 ----------UGAGGUAGUAGGUUGUAUGGUU---------------------------------------------------- 14477 0,0 ----------UGAGGUAGUAGGUUGUAUGGUUa--------------------------------------------------- 804 0,0 ----------UGAGGUAGUAGGUUGUAUGGUUaa-------------------------------------------------- 49 0,0 ----------UGAGGUAGUAGGUUGUAUGGUUau-------------------------------------------------- 42 0,0 ----------UGAGGUAGUAGGUUGUAUGGUUc--------------------------------------------------- 13 0,0 ----------UGAGGUAGUAGGUUGUAUGGUUg--------------------------------------------------- 59 0,0 ----------UGAGGUAGUAGGUUGUAUGGUUU--------------------------------------------------- 844 0,1 ----------UGAGGUAGUAGGUUGUAUGGUUUu-------------------------------------------------- 12 0,1 ----------UGAGGUAGUAGGUUGUAUGGUUUA-------------------------------------------------- 4 0,2 -----------GAGGUAGUAGGUUGUAUGG------------------------------------------------------ 4 1,-2 -----------GAGGUAGUAGGUUGUAUGGU----------------------------------------------------- 59 1,-1 -----------GAGGUAGUAGGUUGUAUGGUa---------------------------------------------------- 16 1,-1 -----------GAGGUAGUAGGUUGUAUGGUaa--------------------------------------------------- 6 1,-1 -----------GAGGUAGUAGGUUGUAUGGUU---------------------------------------------------- 367 1,0 -----------GAGGUAGUAGGUUGUAUGGUUa--------------------------------------------------- 17 1,0 -----------GAGGUAGUAGGUUGUAUGGUUU--------------------------------------------------- 19 1,1 ------------AGGUAGUAGGUUGUAUGGUU---------------------------------------------------- 9 2,0 -------------------------------------------------------CUGUACAACCUUCUAGCUUUCC------- 7 >hsa-let-7d MA:8-29;mi:62-83 Normal ccuaggaAGAGGUAGUAGGUUGCAUAGUUuuagggcagggauuuugcccacaaggagguaaCUAUACGACCUGCUGCCUUUCUuagg -------AGAGGUAGUAGGUUGCAU-------------------------------------------------------------- 58 0,-4 -------AGAGGUAGUAGGUUGCAUA------------------------------------------------------------- 41 0,-3 -------AGAGGUAGUAGGUUGCAUAa------------------------------------------------------------ 19 0,-3 -------AGAGGUAGUAGGUUGCAUAaa----------------------------------------------------------- 4 0,-3 -------AGAGGUAGUAGGUUGCAUAau----------------------------------------------------------- 3 0,-3 -------AGAGGUAGUAGGUUGCAUAu------------------------------------------------------------ 2 0,-3 -------AGAGGUAGUAGGUUGCAUAG------------------------------------------------------------ 396 0,-2 -------AGAGGUAGUAGGUUGCAUAGa----------------------------------------------------------- 120 0,-2 -------AGAGGUAGUAGGUUGCAUAGaa---------------------------------------------------------- 22 0,-2 -------AGAGGUAGUAGGUUGCAUAGau---------------------------------------------------------- 2 0,-2 -------AGAGGUAGUAGGUUGCAUAGc----------------------------------------------------------- 2 0,-2 -------AGAGGUAGUAGGUUGCAUAGU----------------------------------------------------------- 2239 0,-1 -------AGAGGUAGUAGGUUGCAUAGUa---------------------------------------------------------- 54 0,-1 -------AGAGGUAGUAGGUUGCAUAGUaa--------------------------------------------------------- 40 0,-1 -------AGAGGUAGUAGGUUGCAUAGUau--------------------------------------------------------- 11 0,-1 -------AGAGGUAGUAGGUUGCAUAGUU---------------------------------------------------------- 4987 0,0 -------AGAGGUAGUAGGUUGCAUAGUUa--------------------------------------------------------- 131 0,0 -------AGAGGUAGUAGGUUGCAUAGUUaa-------------------------------------------------------- 13 0,0 -------AGAGGUAGUAGGUUGCAUAGUUau-------------------------------------------------------- 2 0,0 -------AGAGGUAGUAGGUUGCAUAGUUc--------------------------------------------------------- 3 0,0 -------AGAGGUAGUAGGUUGCAUAGUUg--------------------------------------------------------- 31 0,0 -------AGAGGUAGUAGGUUGCAUAGUUU--------------------------------------------------------- 327 0,1 -------AGAGGUAGUAGGUUGCAUAGUUUU-------------------------------------------------------- 2 0,2 --------GAGGUAGUAGGUUGCAUAG------------------------------------------------------------ 11 1,-2 --------GAGGUAGUAGGUUGCAUAGaa---------------------------------------------------------- 2 1,-2 --------GAGGUAGUAGGUUGCAUAGU----------------------------------------------------------- 76 1,-1 --------GAGGUAGUAGGUUGCAUAGUa---------------------------------------------------------- 2 1,-1 --------GAGGUAGUAGGUUGCAUAGUU---------------------------------------------------------- 117 1,0 --------GAGGUAGUAGGUUGCAUAGUUa--------------------------------------------------------- 4 1,0 --------GAGGUAGUAGGUUGCAUAGUUU--------------------------------------------------------- 7 1,1 ---------AGGUAGUAGGUUGCAUAGUU---------------------------------------------------------- 2 2,0 -------------------------------------------------------------CUAUACGACCUGCUGCCUUU------ 37 0,-2 -------------------------------------------------------------CUAUACGACCUGCUGCCUUUC----- 29 0,-1 -------------------------------------------------------------CUAUACGACCUGCUGCCUUUCa---- 4 0,-1 -------------------------------------------------------------CUAUACGACCUGCUGCCUUUCU---- 160 0,0 -------------------------------------------------------------CUAUACGACCUGCUGCCUUUCUU--- 2 0,1 --------------------------------------------------------------UAUACGACCUGCUGCCUUU------ 2 1,-2 --------------------------------------------------------------UAUACGACCUGCUGCCUUUC----- 2 1,-1 --------------------------------------------------------------UAUACGACCUGCUGCCUUUCU---- 6 1,0 >hsa-let-7e MA:8-29;mi:53-74 Normal cccgggcUGAGGUAGGAGGUUGUAUAGUUgaggaggacacccaaggagaucaCUAUACGGCCUCCUAGCUUUCCccagg ------CUGAGGUAGGAGGUUGUAUAGU--------------------------------------------------- 2 -1,-1 ------CUGAGGUAGGAGGUUGUAUAGUU-------------------------------------------------- 2 -1,0 -------UGAGGUAGGAGGUUGUAU------------------------------------------------------ 40 0,-4 -------UGAGGUAGGAGGUUGUAUA----------------------------------------------------- 5 0,-3 -------UGAGGUAGGAGGUUGUAUAa---------------------------------------------------- 11 0,-3 -------UGAGGUAGGAGGUUGUAUAau--------------------------------------------------- 2 0,-3 -------UGAGGUAGGAGGUUGUAUAG---------------------------------------------------- 110 0,-2 -------UGAGGUAGGAGGUUGUAUAGa--------------------------------------------------- 65 0,-2 -------UGAGGUAGGAGGUUGUAUAGaa-------------------------------------------------- 28 0,-2 -------UGAGGUAGGAGGUUGUAUAGau-------------------------------------------------- 2 0,-2 -------UGAGGUAGGAGGUUGUAUAGc--------------------------------------------------- 2 0,-2 -------UGAGGUAGGAGGUUGUAUAGU--------------------------------------------------- 796 0,-1 -------UGAGGUAGGAGGUUGUAUAGUa-------------------------------------------------- 56 0,-1 -------UGAGGUAGGAGGUUGUAUAGUaa------------------------------------------------- 42 0,-1 -------UGAGGUAGGAGGUUGUAUAGUau------------------------------------------------- 17 0,-1 -------UGAGGUAGGAGGUUGUAUAGUc-------------------------------------------------- 2 0,-1 -------UGAGGUAGGAGGUUGUAUAGUU-------------------------------------------------- 1702 0,0 -------UGAGGUAGGAGGUUGUAUAGUUa------------------------------------------------- 125 0,0 -------UGAGGUAGGAGGUUGUAUAGUUaa------------------------------------------------ 10 0,0 -------UGAGGUAGGAGGUUGUAUAGUUau------------------------------------------------ 2 0,0 -------UGAGGUAGGAGGUUGUAUAGUUu------------------------------------------------- 180 0,0 -------UGAGGUAGGAGGUUGUAUAGUUuu------------------------------------------------ 2 0,0 -------UGAGGUAGGAGGUUGUAUAGUUG------------------------------------------------- 38 0,1 -------UGAGGUAGGAGGUUGUAUAGUUGu------------------------------------------------ 7 0,1 -------UGAGGUAGGAGGUUGUAUAGUUGA------------------------------------------------ 4 0,2 --------GAGGUAGGAGGUUGUAUAGU--------------------------------------------------- 11 1,-1 --------GAGGUAGGAGGUUGUAUAGUU-------------------------------------------------- 37 1,0 --------GAGGUAGGAGGUUGUAUAGUUu------------------------------------------------- 4 1,0 ----------------------------------------------------CUAUACGGCCUCCUAGCUUUC------ 2 0,-1 ----------------------------------------------------CUAUACGGCCUCCUAGCUUUCC----- 9 0,0 >hsa-let-7f-1 MA:7-28;mi:63-84 Normal ucagagUGAGGUAGUAGAUUGUAUAGUUgugggguagugauuuuacccuguucaggagauaaCUAUACAAUCUAUUGCCUUCCCuga ------UGAGGUAGUAGAUUGUAU--------------------------------------------------------------- 744 0,-4 ------UGAGGUAGUAGAUUGUAUA-------------------------------------------------------------- 301 0,-3 ------UGAGGUAGUAGAUUGUAUAa------------------------------------------------------------- 132 0,-3 ------UGAGGUAGUAGAUUGUAUAaa------------------------------------------------------------ 36 0,-3 ------UGAGGUAGUAGAUUGUAUAau------------------------------------------------------------ 11 0,-3 ------UGAGGUAGUAGAUUGUAUAc------------------------------------------------------------- 2 0,-3 ------UGAGGUAGUAGAUUGUAUAu------------------------------------------------------------- 12 0,-3 ------UGAGGUAGUAGAUUGUAUAuu------------------------------------------------------------ 33 0,-3 ------UGAGGUAGUAGAUUGUAUAG------------------------------------------------------------- 2099 0,-2 ------UGAGGUAGUAGAUUGUAUAGa------------------------------------------------------------ 341 0,-2 ------UGAGGUAGUAGAUUGUAUAGaa----------------------------------------------------------- 61 0,-2 ------UGAGGUAGUAGAUUGUAUAGau----------------------------------------------------------- 8 0,-2 ------UGAGGUAGUAGAUUGUAUAGc------------------------------------------------------------ 8 0,-2 ------UGAGGUAGUAGAUUGUAUAGg------------------------------------------------------------ 17 0,-2 ------UGAGGUAGUAGAUUGUAUAGU------------------------------------------------------------ 12747 0,-1 ------UGAGGUAGUAGAUUGUAUAGUa----------------------------------------------------------- 378 0,-1 ------UGAGGUAGUAGAUUGUAUAGUaa---------------------------------------------------------- 178 0,-1 ------UGAGGUAGUAGAUUGUAUAGUau---------------------------------------------------------- 22 0,-1 ------UGAGGUAGUAGAUUGUAUAGUc----------------------------------------------------------- 49 0,-1 ------UGAGGUAGUAGAUUGUAUAGUg----------------------------------------------------------- 16 0,-1 ------UGAGGUAGUAGAUUGUAUAGUU----------------------------------------------------------- 34704 0,0 ------UGAGGUAGUAGAUUGUAUAGUUa---------------------------------------------------------- 837 0,0 ------UGAGGUAGUAGAUUGUAUAGUUaa--------------------------------------------------------- 49 0,0 ------UGAGGUAGUAGAUUGUAUAGUUau--------------------------------------------------------- 8 0,0 ------UGAGGUAGUAGAUUGUAUAGUUc---------------------------------------------------------- 4 0,0 ------UGAGGUAGUAGAUUGUAUAGUUG---------------------------------------------------------- 176 0,1 ------UGAGGUAGUAGAUUGUAUAGUUGa--------------------------------------------------------- 3 0,1 ------UGAGGUAGUAGAUUGUAUAGUUGU--------------------------------------------------------- 6 0,2 -------GAGGUAGUAGAUUGUAUA-------------------------------------------------------------- 6 1,-3 -------GAGGUAGUAGAUUGUAUAu------------------------------------------------------------- 2 1,-3 -------GAGGUAGUAGAUUGUAUAuu------------------------------------------------------------ 2 1,-3 -------GAGGUAGUAGAUUGUAUAG------------------------------------------------------------- 52 1,-2 -------GAGGUAGUAGAUUGUAUAGa------------------------------------------------------------ 11 1,-2 -------GAGGUAGUAGAUUGUAUAGaa----------------------------------------------------------- 2 1,-2 -------GAGGUAGUAGAUUGUAUAGU------------------------------------------------------------ 389 1,-1 -------GAGGUAGUAGAUUGUAUAGUa----------------------------------------------------------- 12 1,-1 -------GAGGUAGUAGAUUGUAUAGUaa---------------------------------------------------------- 4 1,-1 -------GAGGUAGUAGAUUGUAUAGUU----------------------------------------------------------- 1061 1,0 -------GAGGUAGUAGAUUGUAUAGUUa---------------------------------------------------------- 24 1,0 -------GAGGUAGUAGAUUGUAUAGUUG---------------------------------------------------------- 2 1,1 --------AGGUAGUAGAUUGUAUAGU------------------------------------------------------------ 2 2,-1 --------AGGUAGUAGAUUGUAUAGUU----------------------------------------------------------- 17 2,0 --------AGGUAGUAGAUUGUAUAGUUGU--------------------------------------------------------- 2 2,2 --------------------------------------------------------------CUAUACAAUCUAUUGCCUUC----- 7 0,-2 --------------------------------------------------------------CUAUACAAUCUAUUGCCUUCu---- 2 0,-2 --------------------------------------------------------------CUAUACAAUCUAUUGCCUUCC---- 4 0,-1 --------------------------------------------------------------CUAUACAAUCUAUUGCCUUCCu--- 2 0,-1 >hsa-let-7f-2 MA:8-29;mi:58-79 Normal ugugggaUGAGGUAGUAGAUUGUAUAGUUuuagggucauaccccaucuuggagauaaCUAUACAGUCUACUGUCUUUCCcacg ------AUGAGGUAGUAGAUUGUAUAGU------------------------------------------------------- 3 -1,-1 ------AUGAGGUAGUAGAUUGUAUAGUU------------------------------------------------------ 7 -1,0 -------UGAGGUAGUAGAUUGUAU---------------------------------------------------------- 744 0,-4 -------UGAGGUAGUAGAUUGUAUA--------------------------------------------------------- 301 0,-3 -------UGAGGUAGUAGAUUGUAUAa-------------------------------------------------------- 132 0,-3 -------UGAGGUAGUAGAUUGUAUAaa------------------------------------------------------- 36 0,-3 -------UGAGGUAGUAGAUUGUAUAau------------------------------------------------------- 11 0,-3 -------UGAGGUAGUAGAUUGUAUAc-------------------------------------------------------- 2 0,-3 -------UGAGGUAGUAGAUUGUAUAu-------------------------------------------------------- 12 0,-3 -------UGAGGUAGUAGAUUGUAUAuu------------------------------------------------------- 33 0,-3 -------UGAGGUAGUAGAUUGUAUAG-------------------------------------------------------- 2099 0,-2 -------UGAGGUAGUAGAUUGUAUAGa------------------------------------------------------- 341 0,-2 -------UGAGGUAGUAGAUUGUAUAGaa------------------------------------------------------ 61 0,-2 -------UGAGGUAGUAGAUUGUAUAGau------------------------------------------------------ 8 0,-2 -------UGAGGUAGUAGAUUGUAUAGc------------------------------------------------------- 8 0,-2 -------UGAGGUAGUAGAUUGUAUAGg------------------------------------------------------- 17 0,-2 -------UGAGGUAGUAGAUUGUAUAGU------------------------------------------------------- 12747 0,-1 -------UGAGGUAGUAGAUUGUAUAGUa------------------------------------------------------ 378 0,-1 -------UGAGGUAGUAGAUUGUAUAGUaa----------------------------------------------------- 178 0,-1 -------UGAGGUAGUAGAUUGUAUAGUau----------------------------------------------------- 22 0,-1 -------UGAGGUAGUAGAUUGUAUAGUc------------------------------------------------------ 49 0,-1 -------UGAGGUAGUAGAUUGUAUAGUg------------------------------------------------------ 16 0,-1 -------UGAGGUAGUAGAUUGUAUAGUU------------------------------------------------------ 34704 0,0 -------UGAGGUAGUAGAUUGUAUAGUUa----------------------------------------------------- 837 0,0 -------UGAGGUAGUAGAUUGUAUAGUUaa---------------------------------------------------- 49 0,0 -------UGAGGUAGUAGAUUGUAUAGUUau---------------------------------------------------- 8 0,0 -------UGAGGUAGUAGAUUGUAUAGUUc----------------------------------------------------- 4 0,0 -------UGAGGUAGUAGAUUGUAUAGUUU----------------------------------------------------- 865 0,1 --------GAGGUAGUAGAUUGUAUA--------------------------------------------------------- 6 1,-3 --------GAGGUAGUAGAUUGUAUAu-------------------------------------------------------- 2 1,-3 --------GAGGUAGUAGAUUGUAUAuu------------------------------------------------------- 2 1,-3 --------GAGGUAGUAGAUUGUAUAG-------------------------------------------------------- 52 1,-2 --------GAGGUAGUAGAUUGUAUAGa------------------------------------------------------- 11 1,-2 --------GAGGUAGUAGAUUGUAUAGaa------------------------------------------------------ 2 1,-2 --------GAGGUAGUAGAUUGUAUAGU------------------------------------------------------- 389 1,-1 --------GAGGUAGUAGAUUGUAUAGUa------------------------------------------------------ 12 1,-1 --------GAGGUAGUAGAUUGUAUAGUaa----------------------------------------------------- 4 1,-1 --------GAGGUAGUAGAUUGUAUAGUU------------------------------------------------------ 1061 1,0 --------GAGGUAGUAGAUUGUAUAGUUa----------------------------------------------------- 24 1,0 --------GAGGUAGUAGAUUGUAUAGUUU----------------------------------------------------- 24 1,1 ---------AGGUAGUAGAUUGUAUAGU------------------------------------------------------- 2 2,-1 ---------AGGUAGUAGAUUGUAUAGUU------------------------------------------------------ 17 2,0 ---------------------------------------------------------CUAUACAGUCUACUGUCUUU------ 12 0,-2 ---------------------------------------------------------CUAUACAGUCUACUGUCUUUCu---- 7 0,-1 >hsa-let-7g MA:5-26;mi:62-82 Normal aggcUGAGGUAGUAGUUUGUACAGUUugagggucuaugauaccacccgguacaggagauaaCUGUACAGGCCACUGCCUUGCca ---CUGAGGUAGUAGUUUGUACAG------------------------------------------------------------ 2 -1,-2 ---CUGAGGUAGUAGUUUGUACAGU----------------------------------------------------------- 13 -1,-1 ---CUGAGGUAGUAGUUUGUACAGUU---------------------------------------------------------- 81 -1,0 ---CUGAGGUAGUAGUUUGUACAGUUa--------------------------------------------------------- 3 -1,0 ----UGAGGUAGUAGUUUGUAC-------------------------------------------------------------- 140 0,-4 ----UGAGGUAGUAGUUUGUACA------------------------------------------------------------- 141 0,-3 ----UGAGGUAGUAGUUUGUACAa------------------------------------------------------------ 7 0,-3 ----UGAGGUAGUAGUUUGUACAau----------------------------------------------------------- 5 0,-3 ----UGAGGUAGUAGUUUGUACAuu----------------------------------------------------------- 8 0,-3 ----UGAGGUAGUAGUUUGUACAG------------------------------------------------------------ 348 0,-2 ----UGAGGUAGUAGUUUGUACAGa----------------------------------------------------------- 54 0,-2 ----UGAGGUAGUAGUUUGUACAGaa---------------------------------------------------------- 7 0,-2 ----UGAGGUAGUAGUUUGUACAGau---------------------------------------------------------- 7 0,-2 ----UGAGGUAGUAGUUUGUACAGU----------------------------------------------------------- 3617 0,-1 ----UGAGGUAGUAGUUUGUACAGUa---------------------------------------------------------- 104 0,-1 ----UGAGGUAGUAGUUUGUACAGUaa--------------------------------------------------------- 25 0,-1 ----UGAGGUAGUAGUUUGUACAGUau--------------------------------------------------------- 7 0,-1 ----UGAGGUAGUAGUUUGUACAGUc---------------------------------------------------------- 14 0,-1 ----UGAGGUAGUAGUUUGUACAGUU---------------------------------------------------------- 12348 0,0 ----UGAGGUAGUAGUUUGUACAGUUa--------------------------------------------------------- 452 0,0 ----UGAGGUAGUAGUUUGUACAGUUaa-------------------------------------------------------- 14 0,0 ----UGAGGUAGUAGUUUGUACAGUUau-------------------------------------------------------- 3 0,0 ----UGAGGUAGUAGUUUGUACAGUUc--------------------------------------------------------- 3 0,0 ----UGAGGUAGUAGUUUGUACAGUUg--------------------------------------------------------- 45 0,0 ----UGAGGUAGUAGUUUGUACAGUUU--------------------------------------------------------- 442 0,1 -----GAGGUAGUAGUUUGUACA------------------------------------------------------------- 3 1,-3 -----GAGGUAGUAGUUUGUACAG------------------------------------------------------------ 11 1,-2 -----GAGGUAGUAGUUUGUACAGU----------------------------------------------------------- 132 1,-1 -----GAGGUAGUAGUUUGUACAGUU---------------------------------------------------------- 453 1,0 -----GAGGUAGUAGUUUGUACAGUUa--------------------------------------------------------- 8 1,0 -----GAGGUAGUAGUUUGUACAGUUU--------------------------------------------------------- 11 1,1 ------AGGUAGUAGUUUGUACAGUU---------------------------------------------------------- 6 2,0 -------------------------------------------------------------CUGUACAGGCCACUGCCUUGu-- 2 0,-1 -------------------------------------------------------------CUGUACAGGCCACUGCCUUGC-- 12 0,0 -------------------------------------------------------------CUGUACAGGCCACUGCCUUGCa- 2 0,0 -------------------------------------------------------------CUGUACAGGCCACUGCCUUGCu- 32 0,0 >hsa-let-7i MA:6-27;mi:62-83 Normal cuggcUGAGGUAGUAGUUUGUGCUGUUggucggguugugacauugcccgcuguggagauaaCUGCGCAAGCUACUGCCUUGCUa ----CUGAGGUAGUAGUUUGUGCUGUU--------------------------------------------------------- 27 -1,0 ----CUGAGGUAGUAGUUUGUGCUGUUa-------------------------------------------------------- 11 -1,0 -----UGAGGUAGUAGUUUGUGC------------------------------------------------------------- 97 0,-4 -----UGAGGUAGUAGUUUGUGCaa----------------------------------------------------------- 2 0,-4 -----UGAGGUAGUAGUUUGUGCU------------------------------------------------------------ 170 0,-3 -----UGAGGUAGUAGUUUGUGCUa----------------------------------------------------------- 18 0,-3 -----UGAGGUAGUAGUUUGUGCUaa---------------------------------------------------------- 6 0,-3 -----UGAGGUAGUAGUUUGUGCUau---------------------------------------------------------- 2 0,-3 -----UGAGGUAGUAGUUUGUGCUuu---------------------------------------------------------- 20 0,-3 -----UGAGGUAGUAGUUUGUGCUG----------------------------------------------------------- 456 0,-2 -----UGAGGUAGUAGUUUGUGCUGa---------------------------------------------------------- 50 0,-2 -----UGAGGUAGUAGUUUGUGCUGaa--------------------------------------------------------- 14 0,-2 -----UGAGGUAGUAGUUUGUGCUGau--------------------------------------------------------- 3 0,-2 -----UGAGGUAGUAGUUUGUGCUGc---------------------------------------------------------- 2 0,-2 -----UGAGGUAGUAGUUUGUGCUGU---------------------------------------------------------- 2571 0,-1 -----UGAGGUAGUAGUUUGUGCUGUa--------------------------------------------------------- 113 0,-1 -----UGAGGUAGUAGUUUGUGCUGUaa-------------------------------------------------------- 149 0,-1 -----UGAGGUAGUAGUUUGUGCUGUau-------------------------------------------------------- 44 0,-1 -----UGAGGUAGUAGUUUGUGCUGUc--------------------------------------------------------- 13 0,-1 -----UGAGGUAGUAGUUUGUGCUGUg--------------------------------------------------------- 3 0,-1 -----UGAGGUAGUAGUUUGUGCUGUU--------------------------------------------------------- 12886 0,0 -----UGAGGUAGUAGUUUGUGCUGUUa-------------------------------------------------------- 6603 0,0 -----UGAGGUAGUAGUUUGUGCUGUUaa------------------------------------------------------- 94 0,0 -----UGAGGUAGUAGUUUGUGCUGUUau------------------------------------------------------- 147 0,0 -----UGAGGUAGUAGUUUGUGCUGUUc-------------------------------------------------------- 21 0,0 -----UGAGGUAGUAGUUUGUGCUGUUu-------------------------------------------------------- 1989 0,0 -----UGAGGUAGUAGUUUGUGCUGUUuu------------------------------------------------------- 24 0,0 -----UGAGGUAGUAGUUUGUGCUGUUG-------------------------------------------------------- 179 0,1 -----UGAGGUAGUAGUUUGUGCUGUUGa------------------------------------------------------- 19 0,1 -----UGAGGUAGUAGUUUGUGCUGUUGu------------------------------------------------------- 7 0,1 ------GAGGUAGUAGUUUGUGCU------------------------------------------------------------ 4 1,-3 ------GAGGUAGUAGUUUGUGCUG----------------------------------------------------------- 10 1,-2 ------GAGGUAGUAGUUUGUGCUGU---------------------------------------------------------- 96 1,-1 ------GAGGUAGUAGUUUGUGCUGUa--------------------------------------------------------- 4 1,-1 ------GAGGUAGUAGUUUGUGCUGUaa-------------------------------------------------------- 4 1,-1 ------GAGGUAGUAGUUUGUGCUGUU--------------------------------------------------------- 359 1,0 ------GAGGUAGUAGUUUGUGCUGUUa-------------------------------------------------------- 175 1,0 ------GAGGUAGUAGUUUGUGCUGUUau------------------------------------------------------- 4 1,0 ------GAGGUAGUAGUUUGUGCUGUUu-------------------------------------------------------- 52 1,0 -------AGGUAGUAGUUUGUGCUGU---------------------------------------------------------- 2 2,-1 -------AGGUAGUAGUUUGUGCUGUU--------------------------------------------------------- 14 2,0 -------AGGUAGUAGUUUGUGCUGUUa-------------------------------------------------------- 3 2,0 -------------------------------------------------------------CUGCGCAAGCUACUGCCU----- 2 0,-4 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUG--- 53 0,-2 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGa-- 7 0,-2 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGu-- 4 0,-2 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGuu- 2 0,-2 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGC-- 109 0,-1 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGCa- 3 0,-1 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGCU- 306 0,0 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGCUu 15 0,0 --------------------------------------------------------------UGCGCAAGCUACUGCCUUGa-- 2 1,-2 --------------------------------------------------------------UGCGCAAGCUACUGCCUUGCU- 12 1,0 >hsa-mir-1-1 3pM:46-67 Normal ugggaaacauacuucuuuauaugcccauauggaccugcuaagcuaUGGAAUGUAAAGAAGUAUGUAUcuca ---------------------------------------------UGGAAUGUAAAGAAGUAUGU------ 13 0,-2 ---------------------------------------------UGGAAUGUAAAGAAGUAUGUA----- 2 0,-1 ---------------------------------------------UGGAAUGUAAAGAAGUAUGUAc---- 6 0,-1 ---------------------------------------------UGGAAUGUAAAGAAGUAUGUAU---- 166 0,0 ----------------------------------------------GGAAUGUAAAGAAGUAUGUAU---- 4 1,0 >hsa-mir-1-2 3pM:53-74 Normal accuacucagaguacauacuucuuuauguacccauaugaacauacaaugcuaUGGAAUGUAAAGAAGUAUGUAUuuuugguaggc ----------------------------------------------------UGGAAUGUAAAGAAGUAUGU------------- 13 0,-2 ----------------------------------------------------UGGAAUGUAAAGAAGUAUGUA------------ 2 0,-1 ----------------------------------------------------UGGAAUGUAAAGAAGUAUGUAc----------- 6 0,-1 ----------------------------------------------------UGGAAUGUAAAGAAGUAUGUAU----------- 166 0,0 ----------------------------------------------------UGGAAUGUAAAGAAGUAUGUAUU---------- 3 0,1 -----------------------------------------------------GGAAUGUAAAGAAGUAUGUAU----------- 4 1,0 >hsa-mir-100 MA:13-34;mi:48-69 Normal ccuguugccacaAACCCGUAGAUCCGAACUUGUGguauuaguccgcaCAAGCUUGUAUCUAUAGGUAUGugucuguuagg ------------AACCCGUAGAUCCGAACU-------------------------------------------------- 125 0,-4 ------------AACCCGUAGAUCCGAACUU------------------------------------------------- 145 0,-3 ------------AACCCGUAGAUCCGAACUUau----------------------------------------------- 7 0,-3 ------------AACCCGUAGAUCCGAACUUuu----------------------------------------------- 4 0,-3 ------------AACCCGUAGAUCCGAACUUG------------------------------------------------ 276 0,-2 ------------AACCCGUAGAUCCGAACUUGa----------------------------------------------- 42 0,-2 ------------AACCCGUAGAUCCGAACUUGc----------------------------------------------- 20 0,-2 ------------AACCCGUAGAUCCGAACUUGU----------------------------------------------- 7755 0,-1 ------------AACCCGUAGAUCCGAACUUGUa---------------------------------------------- 31 0,-1 ------------AACCCGUAGAUCCGAACUUGUaa--------------------------------------------- 4 0,-1 ------------AACCCGUAGAUCCGAACUUGUc---------------------------------------------- 5 0,-1 ------------AACCCGUAGAUCCGAACUUGUu---------------------------------------------- 29 0,-1 ------------AACCCGUAGAUCCGAACUUGUG---------------------------------------------- 6376 0,0 ------------AACCCGUAGAUCCGAACUUGUGa--------------------------------------------- 3262 0,0 ------------AACCCGUAGAUCCGAACUUGUGaa-------------------------------------------- 53 0,0 ------------AACCCGUAGAUCCGAACUUGUGau-------------------------------------------- 3 0,0 ------------AACCCGUAGAUCCGAACUUGUGc--------------------------------------------- 10 0,0 ------------AACCCGUAGAUCCGAACUUGUGu--------------------------------------------- 1199 0,0 ------------AACCCGUAGAUCCGAACUUGUGG--------------------------------------------- 34 0,1 -------------ACCCGUAGAUCCGAACUUG------------------------------------------------ 9 1,-2 -------------ACCCGUAGAUCCGAACUUGU----------------------------------------------- 270 1,-1 -------------ACCCGUAGAUCCGAACUUGUG---------------------------------------------- 231 1,0 -------------ACCCGUAGAUCCGAACUUGUGa--------------------------------------------- 101 1,0 -------------ACCCGUAGAUCCGAACUUGUGu--------------------------------------------- 39 1,0 -------------ACCCGUAGAUCCGAACUUGUGGa-------------------------------------------- 2 1,1 --------------CCCGUAGAUCCGAACUUGU----------------------------------------------- 2 2,-1 >hsa-mir-101-1 mi:11-32;MA:47-67 Normal ugcccuggcuCAGUUAUCACAGUGCUGAUGCUgucuauucuaaaggUACAGUACUGUGAUAACUGAAggauggca ---------UCAGUUAUCACAGUGCUGA----------------------------------------------- 2 -1,-4 ---------UCAGUUAUCACAGUGCUGAaa--------------------------------------------- 2 -1,-4 ---------UCAGUUAUCACAGUGCUGAU---------------------------------------------- 2 -1,-3 ---------UCAGUUAUCACAGUGCUGAUG--------------------------------------------- 69 -1,-2 ---------UCAGUUAUCACAGUGCUGAUGa-------------------------------------------- 17 -1,-2 ---------UCAGUUAUCACAGUGCUGAUGC-------------------------------------------- 276 -1,-1 ---------UCAGUUAUCACAGUGCUGAUGCa------------------------------------------- 2 -1,-1 ---------UCAGUUAUCACAGUGCUGAUGCU------------------------------------------- 48 -1,0 ----------CAGUUAUCACAGUGCUGAUG--------------------------------------------- 17 0,-2 ----------CAGUUAUCACAGUGCUGAUGu-------------------------------------------- 5 0,-2 ----------CAGUUAUCACAGUGCUGAUGC-------------------------------------------- 42 0,-1 ----------CAGUUAUCACAGUGCUGAUGCU------------------------------------------- 26 0,0 -----------AGUUAUCACAGUGCUGAUG--------------------------------------------- 2 1,-2 -----------AGUUAUCACAGUGCUGAUGC-------------------------------------------- 3 1,-1 --------------------------------------------GGUACAGUACUGUGAUAACUGAA-------- 5 -2,0 ---------------------------------------------GUACAGUACUGUGAUAAC------------ 30 -1,-4 ---------------------------------------------GUACAGUACUGUGAUAACa----------- 9 -1,-4 ---------------------------------------------GUACAGUACUGUGAUAACU----------- 219 -1,-3 ---------------------------------------------GUACAGUACUGUGAUAACUa---------- 4 -1,-3 ---------------------------------------------GUACAGUACUGUGAUAACUaa--------- 9 -1,-3 ---------------------------------------------GUACAGUACUGUGAUAACUu---------- 2 -1,-3 ---------------------------------------------GUACAGUACUGUGAUAACUG---------- 424 -1,-2 ---------------------------------------------GUACAGUACUGUGAUAACUGc--------- 4 -1,-2 ---------------------------------------------GUACAGUACUGUGAUAACUGg--------- 4 -1,-2 ---------------------------------------------GUACAGUACUGUGAUAACUGu--------- 133 -1,-2 ---------------------------------------------GUACAGUACUGUGAUAACUGA--------- 4551 -1,-1 ---------------------------------------------GUACAGUACUGUGAUAACUGAc-------- 70 -1,-1 ---------------------------------------------GUACAGUACUGUGAUAACUGAg-------- 11 -1,-1 ---------------------------------------------GUACAGUACUGUGAUAACUGAu-------- 116 -1,-1 ---------------------------------------------GUACAGUACUGUGAUAACUGAA-------- 2501 -1,0 ---------------------------------------------GUACAGUACUGUGAUAACUGAAa------- 636 -1,0 ---------------------------------------------GUACAGUACUGUGAUAACUGAAaa------ 12 -1,0 ---------------------------------------------GUACAGUACUGUGAUAACUGAAc------- 4 -1,0 ---------------------------------------------GUACAGUACUGUGAUAACUGAAu------- 197 -1,0 ---------------------------------------------GUACAGUACUGUGAUAACUGAAG------- 60 -1,1 ----------------------------------------------UACAGUACUGUGAUAACU----------- 176 0,-3 ----------------------------------------------UACAGUACUGUGAUAACUaa--------- 4 0,-3 ----------------------------------------------UACAGUACUGUGAUAACUG---------- 305 0,-2 ----------------------------------------------UACAGUACUGUGAUAACUGc--------- 4 0,-2 ----------------------------------------------UACAGUACUGUGAUAACUGu--------- 67 0,-2 ----------------------------------------------UACAGUACUGUGAUAACUGA--------- 2490 0,-1 ----------------------------------------------UACAGUACUGUGAUAACUGAc-------- 43 0,-1 ----------------------------------------------UACAGUACUGUGAUAACUGAg-------- 2 0,-1 ----------------------------------------------UACAGUACUGUGAUAACUGAu-------- 66 0,-1 ----------------------------------------------UACAGUACUGUGAUAACUGAuu------- 118 0,-1 ----------------------------------------------UACAGUACUGUGAUAACUGAA-------- 2298 0,0 ----------------------------------------------UACAGUACUGUGAUAACUGAAa------- 1416 0,0 ----------------------------------------------UACAGUACUGUGAUAACUGAAaa------ 84 0,0 ----------------------------------------------UACAGUACUGUGAUAACUGAAau------ 8 0,0 ----------------------------------------------UACAGUACUGUGAUAACUGAAc------- 30 0,0 ----------------------------------------------UACAGUACUGUGAUAACUGAAu------- 2838 0,0 ----------------------------------------------UACAGUACUGUGAUAACUGAAuu------ 31 0,0 ----------------------------------------------UACAGUACUGUGAUAACUGAAG------- 5930 0,1 ----------------------------------------------UACAGUACUGUGAUAACUGAAGc------ 2 0,1 ----------------------------------------------UACAGUACUGUGAUAACUGAAGu------ 357 0,1 ----------------------------------------------UACAGUACUGUGAUAACUGAAGuu----- 4 0,1 ----------------------------------------------UACAGUACUGUGAUAACUGAAGG------ 3 0,2 -----------------------------------------------ACAGUACUGUGAUAACUG---------- 13 1,-2 -----------------------------------------------ACAGUACUGUGAUAACUGA--------- 101 1,-1 -----------------------------------------------ACAGUACUGUGAUAACUGAc-------- 2 1,-1 -----------------------------------------------ACAGUACUGUGAUAACUGAu-------- 3 1,-1 -----------------------------------------------ACAGUACUGUGAUAACUGAA-------- 90 1,0 -----------------------------------------------ACAGUACUGUGAUAACUGAAa------- 73 1,0 -----------------------------------------------ACAGUACUGUGAUAACUGAAaa------ 4 1,0 -----------------------------------------------ACAGUACUGUGAUAACUGAAu------- 128 1,0 -----------------------------------------------ACAGUACUGUGAUAACUGAAuu------ 3 1,0 -----------------------------------------------ACAGUACUGUGAUAACUGAAG------- 267 1,1 -----------------------------------------------ACAGUACUGUGAUAACUGAAGu------ 32 1,1 ------------------------------------------------CAGUACUGUGAUAACUGA--------- 3 2,-1 ------------------------------------------------CAGUACUGUGAUAACUGAA-------- 5 2,0 ------------------------------------------------CAGUACUGUGAUAACUGAAa------- 2 2,0 ------------------------------------------------CAGUACUGUGAUAACUGAAu------- 9 2,0 ------------------------------------------------CAGUACUGUGAUAACUGAAG------- 20 2,1 ------------------------------------------------CAGUACUGUGAUAACUGAAGu------ 2 2,1 >hsa-mir-101-2 3pM:49-69 Normal acuguccuuuuucgguuaucaugguaccgaugcuguauaucugaaaggUACAGUACUGUGAUAACUGAAgaaugguggu -----------UCGGUUAUCAUGGUACCGAUG----------------------------------------------- 3 ----------------------------------------------GGUACAGUACUGUGAUAACUGAA---------- 5 -2,0 -----------------------------------------------GUACAGUACUGUGAUAAC-------------- 30 -1,-4 -----------------------------------------------GUACAGUACUGUGAUAACa------------- 9 -1,-4 -----------------------------------------------GUACAGUACUGUGAUAACU------------- 219 -1,-3 -----------------------------------------------GUACAGUACUGUGAUAACUa------------ 4 -1,-3 -----------------------------------------------GUACAGUACUGUGAUAACUaa----------- 9 -1,-3 -----------------------------------------------GUACAGUACUGUGAUAACUu------------ 2 -1,-3 -----------------------------------------------GUACAGUACUGUGAUAACUG------------ 424 -1,-2 -----------------------------------------------GUACAGUACUGUGAUAACUGc----------- 4 -1,-2 -----------------------------------------------GUACAGUACUGUGAUAACUGg----------- 4 -1,-2 -----------------------------------------------GUACAGUACUGUGAUAACUGu----------- 133 -1,-2 -----------------------------------------------GUACAGUACUGUGAUAACUGA----------- 4551 -1,-1 -----------------------------------------------GUACAGUACUGUGAUAACUGAc---------- 70 -1,-1 -----------------------------------------------GUACAGUACUGUGAUAACUGAg---------- 11 -1,-1 -----------------------------------------------GUACAGUACUGUGAUAACUGAu---------- 116 -1,-1 -----------------------------------------------GUACAGUACUGUGAUAACUGAA---------- 2501 -1,0 -----------------------------------------------GUACAGUACUGUGAUAACUGAAa--------- 636 -1,0 -----------------------------------------------GUACAGUACUGUGAUAACUGAAaa-------- 12 -1,0 -----------------------------------------------GUACAGUACUGUGAUAACUGAAc--------- 4 -1,0 -----------------------------------------------GUACAGUACUGUGAUAACUGAAu--------- 197 -1,0 -----------------------------------------------GUACAGUACUGUGAUAACUGAAG--------- 60 -1,1 ------------------------------------------------UACAGUACUGUGAUAACU------------- 176 0,-3 ------------------------------------------------UACAGUACUGUGAUAACUaa----------- 4 0,-3 ------------------------------------------------UACAGUACUGUGAUAACUG------------ 305 0,-2 ------------------------------------------------UACAGUACUGUGAUAACUGc----------- 4 0,-2 ------------------------------------------------UACAGUACUGUGAUAACUGu----------- 67 0,-2 ------------------------------------------------UACAGUACUGUGAUAACUGA----------- 2490 0,-1 ------------------------------------------------UACAGUACUGUGAUAACUGAc---------- 43 0,-1 ------------------------------------------------UACAGUACUGUGAUAACUGAg---------- 2 0,-1 ------------------------------------------------UACAGUACUGUGAUAACUGAu---------- 66 0,-1 ------------------------------------------------UACAGUACUGUGAUAACUGAuu--------- 118 0,-1 ------------------------------------------------UACAGUACUGUGAUAACUGAA---------- 2298 0,0 ------------------------------------------------UACAGUACUGUGAUAACUGAAa--------- 1416 0,0 ------------------------------------------------UACAGUACUGUGAUAACUGAAaa-------- 84 0,0 ------------------------------------------------UACAGUACUGUGAUAACUGAAau-------- 8 0,0 ------------------------------------------------UACAGUACUGUGAUAACUGAAc--------- 30 0,0 ------------------------------------------------UACAGUACUGUGAUAACUGAAu--------- 2838 0,0 ------------------------------------------------UACAGUACUGUGAUAACUGAAuu-------- 31 0,0 ------------------------------------------------UACAGUACUGUGAUAACUGAAG--------- 5930 0,1 ------------------------------------------------UACAGUACUGUGAUAACUGAAGc-------- 2 0,1 ------------------------------------------------UACAGUACUGUGAUAACUGAAGu-------- 357 0,1 ------------------------------------------------UACAGUACUGUGAUAACUGAAGuu------- 4 0,1 ------------------------------------------------UACAGUACUGUGAUAACUGAAGA-------- 275 0,2 ------------------------------------------------UACAGUACUGUGAUAACUGAAGAA------- 23 0,3 -------------------------------------------------ACAGUACUGUGAUAACUG------------ 13 1,-2 -------------------------------------------------ACAGUACUGUGAUAACUGA----------- 101 1,-1 -------------------------------------------------ACAGUACUGUGAUAACUGAc---------- 2 1,-1 -------------------------------------------------ACAGUACUGUGAUAACUGAu---------- 3 1,-1 -------------------------------------------------ACAGUACUGUGAUAACUGAA---------- 90 1,0 -------------------------------------------------ACAGUACUGUGAUAACUGAAa--------- 73 1,0 -------------------------------------------------ACAGUACUGUGAUAACUGAAaa-------- 4 1,0 -------------------------------------------------ACAGUACUGUGAUAACUGAAu--------- 128 1,0 -------------------------------------------------ACAGUACUGUGAUAACUGAAuu-------- 3 1,0 -------------------------------------------------ACAGUACUGUGAUAACUGAAG--------- 267 1,1 -------------------------------------------------ACAGUACUGUGAUAACUGAAGu-------- 32 1,1 -------------------------------------------------ACAGUACUGUGAUAACUGAAGA-------- 17 1,2 --------------------------------------------------CAGUACUGUGAUAACUGA----------- 3 2,-1 --------------------------------------------------CAGUACUGUGAUAACUGAA---------- 5 2,0 --------------------------------------------------CAGUACUGUGAUAACUGAAa--------- 2 2,0 --------------------------------------------------CAGUACUGUGAUAACUGAAu--------- 9 2,0 --------------------------------------------------CAGUACUGUGAUAACUGAAG--------- 20 2,1 --------------------------------------------------CAGUACUGUGAUAACUGAAGu-------- 2 2,1 >hsa-mir-103a-1 3pM:48-70 Normal uacugcccucggcuucuuuacagugcugccuuguugcauauggaucaAGCAGCAUUGUACAGGGCUAUGAaggcauug -----------------------------------------------AGCAGCAUUGUACAGGGC------------- 56 0,-5 -----------------------------------------------AGCAGCAUUGUACAGGGCc------------ 2 0,-5 -----------------------------------------------AGCAGCAUUGUACAGGGCU------------ 330 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUu----------- 7 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUuu---------- 5 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUA----------- 320 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAa---------- 43 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAaa--------- 21 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAau--------- 2 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAU---------- 1685 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUa--------- 80 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUaa-------- 152 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUau-------- 23 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUu--------- 120 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUuu-------- 26 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUG--------- 1688 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGc-------- 34 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGg-------- 20 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGu-------- 2156 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGuu------- 96 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGA-------- 10993 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAc------- 7 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAg------- 23 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAu------- 436 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAuu------ 7 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAA------- 579 0,1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAAu------ 20 0,1 ------------------------------------------------GCAGCAUUGUACAGGGCU------------ 9 1,-4 ------------------------------------------------GCAGCAUUGUACAGGGCUA----------- 3 1,-3 ------------------------------------------------GCAGCAUUGUACAGGGCUAU---------- 25 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUa--------- 3 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUaa-------- 2 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUau-------- 3 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUu--------- 3 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUG--------- 22 1,-1 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGu-------- 31 1,-1 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGA-------- 225 1,0 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGAu------- 8 1,0 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGAA------- 4 1,1 -------------------------------------------------CAGCAUUGUACAGGGCUAUGu-------- 2 2,-1 -------------------------------------------------CAGCAUUGUACAGGGCUAUGA-------- 38 2,0 -------------------------------------------------CAGCAUUGUACAGGGCUAUGAu------- 2 2,0 >hsa-mir-103a-2 mi:11-33;MA:48-70 Normal uugugcuuucAGCUUCUUUACAGUGCUGCCUUGuagcauucaggucaAGCAGCAUUGUACAGGGCUAUGAaagaacca ----------AGCUUCUUUACAGUGCUGCCU----------------------------------------------- 2 0,-2 ----------AGCUUCUUUACAGUGCUGCCUUu--------------------------------------------- 2 0,-1 ----------AGCUUCUUUACAGUGCUGCCUUG--------------------------------------------- 22 0,0 ----------AGCUUCUUUACAGUGCUGCCUUGa-------------------------------------------- 13 0,0 ----------AGCUUCUUUACAGUGCUGCCUUGU-------------------------------------------- 36 0,1 -----------------------------------------------AGCAGCAUUGUACAGGGC------------- 56 0,-5 -----------------------------------------------AGCAGCAUUGUACAGGGCc------------ 2 0,-5 -----------------------------------------------AGCAGCAUUGUACAGGGCU------------ 330 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUu----------- 7 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUuu---------- 5 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUA----------- 320 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAa---------- 43 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAaa--------- 21 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAau--------- 2 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAU---------- 1685 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUa--------- 80 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUaa-------- 152 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUau-------- 23 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUu--------- 120 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUuu-------- 26 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUG--------- 1688 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGc-------- 34 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGg-------- 20 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGu-------- 2156 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGuu------- 96 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGA-------- 10993 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAc------- 7 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAg------- 23 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAu------- 436 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAuu------ 7 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAA------- 579 0,1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAAu------ 20 0,1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAAA------ 28 0,2 ------------------------------------------------GCAGCAUUGUACAGGGCU------------ 9 1,-4 ------------------------------------------------GCAGCAUUGUACAGGGCUA----------- 3 1,-3 ------------------------------------------------GCAGCAUUGUACAGGGCUAU---------- 25 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUa--------- 3 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUaa-------- 2 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUau-------- 3 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUu--------- 3 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUG--------- 22 1,-1 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGu-------- 31 1,-1 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGA-------- 225 1,0 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGAu------- 8 1,0 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGAA------- 4 1,1 -------------------------------------------------CAGCAUUGUACAGGGCUAUGu-------- 2 2,-1 -------------------------------------------------CAGCAUUGUACAGGGCUAUGA-------- 38 2,0 -------------------------------------------------CAGCAUUGUACAGGGCUAUGAu------- 2 2,0 >hsa-mir-106a MA:13-35;mi:50-71 Normal ccuuggccauguAAAAGUGCUUACAGUGCAGGUAGcuuuuugagaucuaCUGCAAUGUAAGCACUUCUUACauuaccaugg ------------AAAAGUGCUUACAGUGCAGG------------------------------------------------- 10 0,-3 ------------AAAAGUGCUUACAGUGCAGGU------------------------------------------------ 52 0,-2 ------------AAAAGUGCUUACAGUGCAGGUA----------------------------------------------- 40 0,-1 ------------AAAAGUGCUUACAGUGCAGGUAa---------------------------------------------- 6 0,-1 ------------AAAAGUGCUUACAGUGCAGGUAG---------------------------------------------- 67 0,0 ------------AAAAGUGCUUACAGUGCAGGUAGa--------------------------------------------- 3 0,0 -------------AAAGUGCUUACAGUGCAG-------------------------------------------------- 4 1,-4 -------------AAAGUGCUUACAGUGCAGGU------------------------------------------------ 27 1,-2 -------------AAAGUGCUUACAGUGCAGGUA----------------------------------------------- 32 1,-1 -------------AAAGUGCUUACAGUGCAGGUAa---------------------------------------------- 16 1,-1 -------------AAAGUGCUUACAGUGCAGGUAu---------------------------------------------- 12 1,-1 -------------AAAGUGCUUACAGUGCAGGUAG---------------------------------------------- 79 1,0 -------------AAAGUGCUUACAGUGCAGGUAGa--------------------------------------------- 16 1,0 >hsa-mir-106b MA:12-32;mi:52-73 Normal ccugccggggcUAAAGUGCUGACAGUGCAGAUagugguccucuccgugcuaCCGCACUGUGGGUACUUGCUGCuccagcagg ----------CUAAAGUGCUGACAGUGCAGA--------------------------------------------------- 2 -1,-1 ----------CUAAAGUGCUGACAGUGCAGAU-------------------------------------------------- 6 -1,0 -----------UAAAGUGCUGACAGUGCA----------------------------------------------------- 25 0,-3 -----------UAAAGUGCUGACAGUGCAa---------------------------------------------------- 5 0,-3 -----------UAAAGUGCUGACAGUGCAaa--------------------------------------------------- 2 0,-3 -----------UAAAGUGCUGACAGUGCAG---------------------------------------------------- 92 0,-2 -----------UAAAGUGCUGACAGUGCAGc--------------------------------------------------- 2 0,-2 -----------UAAAGUGCUGACAGUGCAGA--------------------------------------------------- 839 0,-1 -----------UAAAGUGCUGACAGUGCAGAa-------------------------------------------------- 66 0,-1 -----------UAAAGUGCUGACAGUGCAGAaa------------------------------------------------- 76 0,-1 -----------UAAAGUGCUGACAGUGCAGAau------------------------------------------------- 2 0,-1 -----------UAAAGUGCUGACAGUGCAGAc-------------------------------------------------- 2 0,-1 -----------UAAAGUGCUGACAGUGCAGAg-------------------------------------------------- 3 0,-1 -----------UAAAGUGCUGACAGUGCAGAU-------------------------------------------------- 1856 0,0 -----------UAAAGUGCUGACAGUGCAGAUc------------------------------------------------- 5 0,0 -----------UAAAGUGCUGACAGUGCAGAUg------------------------------------------------- 18 0,0 -----------UAAAGUGCUGACAGUGCAGAUu------------------------------------------------- 107 0,0 -----------UAAAGUGCUGACAGUGCAGAUA------------------------------------------------- 994 0,1 -----------UAAAGUGCUGACAGUGCAGAUAa------------------------------------------------ 248 0,1 -----------UAAAGUGCUGACAGUGCAGAUAaa----------------------------------------------- 8 0,1 -----------UAAAGUGCUGACAGUGCAGAUAu------------------------------------------------ 65 0,1 -----------UAAAGUGCUGACAGUGCAGAUAG------------------------------------------------ 51 0,2 -----------UAAAGUGCUGACAGUGCAGAUAGU----------------------------------------------- 6 0,3 ------------AAAGUGCUGACAGUGCAGA--------------------------------------------------- 28 1,-1 ------------AAAGUGCUGACAGUGCAGAaa------------------------------------------------- 5 1,-1 ------------AAAGUGCUGACAGUGCAGAU-------------------------------------------------- 56 1,0 ------------AAAGUGCUGACAGUGCAGAUu------------------------------------------------- 4 1,0 ------------AAAGUGCUGACAGUGCAGAUA------------------------------------------------- 35 1,1 ------------AAAGUGCUGACAGUGCAGAUAa------------------------------------------------ 10 1,1 ------------AAAGUGCUGACAGUGCAGAUAu------------------------------------------------ 7 1,1 -------------AAGUGCUGACAGUGCAGA--------------------------------------------------- 2 2,-1 -------------AAGUGCUGACAGUGCAGAU-------------------------------------------------- 5 2,0 -------------AAGUGCUGACAGUGCAGAUAa------------------------------------------------ 2 2,1 -------------------------------------------------UACCGCACUGUGGGUACUUG------------- 2 -2,-4 -------------------------------------------------UACCGCACUGUGGGUACUUGC------------ 3 -2,-3 -------------------------------------------------UACCGCACUGUGGGUACUUGCU----------- 70 -2,-2 --------------------------------------------------ACCGCACUGUGGGUACUUGCa----------- 2 -1,-3 --------------------------------------------------ACCGCACUGUGGGUACUUGCU----------- 7 -1,-2 ---------------------------------------------------CCGCACUGUGGGUACUUG------------- 4 0,-4 ---------------------------------------------------CCGCACUGUGGGUACUUGa------------ 2 0,-4 ---------------------------------------------------CCGCACUGUGGGUACUUGC------------ 15 0,-3 ---------------------------------------------------CCGCACUGUGGGUACUUGCU----------- 164 0,-2 ---------------------------------------------------CCGCACUGUGGGUACUUGCUG---------- 50 0,-1 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGa--------- 24 0,-1 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGaa-------- 2 0,-1 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGu--------- 33 0,-1 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGC--------- 44 0,0 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGCa-------- 6 0,0 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGCU-------- 3 0,1 ----------------------------------------------------CGCACUGUGGGUACUUGCU----------- 7 1,-2 ----------------------------------------------------CGCACUGUGGGUACUUGCUG---------- 3 1,-1 >hsa-mir-107 3pM:50-72 Normal cucucugcuuucagcuucuuuacaguguugccuuguggcauggaguucaAGCAGCAUUGUACAGGGCUAUCAaagcacaga -------------------------------------------------AGCAGCAUUGUACAGGGC-------------- 56 0,-5 -------------------------------------------------AGCAGCAUUGUACAGGGCc------------- 2 0,-5 -------------------------------------------------AGCAGCAUUGUACAGGGCU------------- 330 0,-4 -------------------------------------------------AGCAGCAUUGUACAGGGCUu------------ 7 0,-4 -------------------------------------------------AGCAGCAUUGUACAGGGCUuu----------- 5 0,-4 -------------------------------------------------AGCAGCAUUGUACAGGGCUA------------ 320 0,-3 -------------------------------------------------AGCAGCAUUGUACAGGGCUAa----------- 43 0,-3 -------------------------------------------------AGCAGCAUUGUACAGGGCUAaa---------- 21 0,-3 -------------------------------------------------AGCAGCAUUGUACAGGGCUAau---------- 2 0,-3 -------------------------------------------------AGCAGCAUUGUACAGGGCUAU----------- 1685 0,-2 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUa---------- 80 0,-2 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUaa--------- 152 0,-2 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUau--------- 23 0,-2 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUu---------- 120 0,-2 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUuu--------- 26 0,-2 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUC---------- 38 0,-1 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUCu--------- 7 0,-1 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUCA--------- 81 0,0 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUCAc-------- 2 0,0 --------------------------------------------------GCAGCAUUGUACAGGGCU------------- 9 1,-4 --------------------------------------------------GCAGCAUUGUACAGGGCUA------------ 3 1,-3 --------------------------------------------------GCAGCAUUGUACAGGGCUAU----------- 25 1,-2 --------------------------------------------------GCAGCAUUGUACAGGGCUAUa---------- 3 1,-2 --------------------------------------------------GCAGCAUUGUACAGGGCUAUaa--------- 2 1,-2 --------------------------------------------------GCAGCAUUGUACAGGGCUAUau--------- 3 1,-2 --------------------------------------------------GCAGCAUUGUACAGGGCUAUu---------- 3 1,-2 >hsa-mir-10a MA:22-44;mi:63-84 Normal gaucugucugucuucuguauaUACCCUGUAGAUCCGAAUUUGUGuaaggaauuuuguggucaCAAAUUCGUAUCUAGGGGAAUAuguaguugacauaaacacuccgcucu --------------------AUACCCUGUAGAUCCGAAUUUG-------------------------------------------------------------------- 2 -1,-2 --------------------AUACCCUGUAGAUCCGAAUUUGU------------------------------------------------------------------- 11 -1,-1 ---------------------UACCCUGUAGAUCCGAAUU---------------------------------------------------------------------- 3 0,-4 ---------------------UACCCUGUAGAUCCGAAUUU--------------------------------------------------------------------- 8 0,-3 ---------------------UACCCUGUAGAUCCGAAUUUuu------------------------------------------------------------------- 3 0,-3 ---------------------UACCCUGUAGAUCCGAAUUUG-------------------------------------------------------------------- 71 0,-2 ---------------------UACCCUGUAGAUCCGAAUUUGa------------------------------------------------------------------- 20 0,-2 ---------------------UACCCUGUAGAUCCGAAUUUGg------------------------------------------------------------------- 2 0,-2 ---------------------UACCCUGUAGAUCCGAAUUUGU------------------------------------------------------------------- 994 0,-1 ---------------------UACCCUGUAGAUCCGAAUUUGUa------------------------------------------------------------------ 5 0,-1 ---------------------UACCCUGUAGAUCCGAAUUUGUaa----------------------------------------------------------------- 2 0,-1 ---------------------UACCCUGUAGAUCCGAAUUUGUG------------------------------------------------------------------ 216 0,0 ---------------------UACCCUGUAGAUCCGAAUUUGUGa----------------------------------------------------------------- 42 0,0 ---------------------UACCCUGUAGAUCCGAAUUUGUGU----------------------------------------------------------------- 30 0,1 ----------------------ACCCUGUAGAUCCGAAUU---------------------------------------------------------------------- 2 1,-4 ----------------------ACCCUGUAGAUCCGAAUUU--------------------------------------------------------------------- 13 1,-3 ----------------------ACCCUGUAGAUCCGAAUUUG-------------------------------------------------------------------- 53 1,-2 ----------------------ACCCUGUAGAUCCGAAUUUGa------------------------------------------------------------------- 13 1,-2 ----------------------ACCCUGUAGAUCCGAAUUUGU------------------------------------------------------------------- 689 1,-1 ----------------------ACCCUGUAGAUCCGAAUUUGUa------------------------------------------------------------------ 2 1,-1 ----------------------ACCCUGUAGAUCCGAAUUUGUaa----------------------------------------------------------------- 2 1,-1 ----------------------ACCCUGUAGAUCCGAAUUUGUG------------------------------------------------------------------ 617 1,0 ----------------------ACCCUGUAGAUCCGAAUUUGUGa----------------------------------------------------------------- 383 1,0 ----------------------ACCCUGUAGAUCCGAAUUUGUGaa---------------------------------------------------------------- 4 1,0 ----------------------ACCCUGUAGAUCCGAAUUUGUGc----------------------------------------------------------------- 2 1,0 ----------------------ACCCUGUAGAUCCGAAUUUGUGU----------------------------------------------------------------- 138 1,1 -----------------------CCCUGUAGAUCCGAAUUUGU------------------------------------------------------------------- 7 2,-1 -----------------------CCCUGUAGAUCCGAAUUUGUG------------------------------------------------------------------ 2 2,0 -----------------------CCCUGUAGAUCCGAAUUUGUGa----------------------------------------------------------------- 5 2,0 --------------------------------------------------------------CAAAUUCGUAUCUAGGGGAA---------------------------- 2 0,-2 --------------------------------------------------------------CAAAUUCGUAUCUAGGGGAAaa-------------------------- 2 0,-2 --------------------------------------------------------------CAAAUUCGUAUCUAGGGGAAU--------------------------- 24 0,-1 --------------------------------------------------------------CAAAUUCGUAUCUAGGGGAAUu-------------------------- 2 0,-1 ---------------------------------------------------------------AAAUUCGUAUCUAGGGGAAU--------------------------- 4 1,-1 >hsa-mir-10b MA:27-49;mi:66-87 Normal ccagagguuguaacguugucuauauaUACCCUGUAGAACCGAAUUUGUGugguauccguauagucACAGAUUCGAUUCUAGGGGAAUauauggucgaugcaaaaacuuca --------------------------UACCCUGUAGAACCGAAU------------------------------------------------------------------ 27 0,-5 --------------------------UACCCUGUAGAACCGAAUaa---------------------------------------------------------------- 2 0,-5 --------------------------UACCCUGUAGAACCGAAUU----------------------------------------------------------------- 15 0,-4 --------------------------UACCCUGUAGAACCGAAUUU---------------------------------------------------------------- 76 0,-3 --------------------------UACCCUGUAGAACCGAAUUUaa-------------------------------------------------------------- 2 0,-3 --------------------------UACCCUGUAGAACCGAAUUUau-------------------------------------------------------------- 8 0,-3 --------------------------UACCCUGUAGAACCGAAUUUuu-------------------------------------------------------------- 14 0,-3 --------------------------UACCCUGUAGAACCGAAUUUG--------------------------------------------------------------- 449 0,-2 --------------------------UACCCUGUAGAACCGAAUUUGa-------------------------------------------------------------- 72 0,-2 --------------------------UACCCUGUAGAACCGAAUUUGaa------------------------------------------------------------- 4 0,-2 --------------------------UACCCUGUAGAACCGAAUUUGc-------------------------------------------------------------- 17 0,-2 --------------------------UACCCUGUAGAACCGAAUUUGg-------------------------------------------------------------- 3 0,-2 --------------------------UACCCUGUAGAACCGAAUUUGU-------------------------------------------------------------- 6168 0,-1 --------------------------UACCCUGUAGAACCGAAUUUGUa------------------------------------------------------------- 37 0,-1 --------------------------UACCCUGUAGAACCGAAUUUGUaa------------------------------------------------------------ 4 0,-1 --------------------------UACCCUGUAGAACCGAAUUUGUau------------------------------------------------------------ 2 0,-1 --------------------------UACCCUGUAGAACCGAAUUUGUu------------------------------------------------------------- 10 0,-1 --------------------------UACCCUGUAGAACCGAAUUUGUG------------------------------------------------------------- 695 0,0 --------------------------UACCCUGUAGAACCGAAUUUGUGa------------------------------------------------------------ 160 0,0 --------------------------UACCCUGUAGAACCGAAUUUGUGU------------------------------------------------------------ 79 0,1 ---------------------------ACCCUGUAGAACCGAAUU----------------------------------------------------------------- 11 1,-4 ---------------------------ACCCUGUAGAACCGAAUUU---------------------------------------------------------------- 29 1,-3 ---------------------------ACCCUGUAGAACCGAAUUUG--------------------------------------------------------------- 102 1,-2 ---------------------------ACCCUGUAGAACCGAAUUUGa-------------------------------------------------------------- 27 1,-2 ---------------------------ACCCUGUAGAACCGAAUUUGc-------------------------------------------------------------- 2 1,-2 ---------------------------ACCCUGUAGAACCGAAUUUGg-------------------------------------------------------------- 2 1,-2 ---------------------------ACCCUGUAGAACCGAAUUUGU-------------------------------------------------------------- 1359 1,-1 ---------------------------ACCCUGUAGAACCGAAUUUGUa------------------------------------------------------------- 6 1,-1 ---------------------------ACCCUGUAGAACCGAAUUUGUaa------------------------------------------------------------ 2 1,-1 ---------------------------ACCCUGUAGAACCGAAUUUGUau------------------------------------------------------------ 2 1,-1 ---------------------------ACCCUGUAGAACCGAAUUUGUu------------------------------------------------------------- 4 1,-1 ---------------------------ACCCUGUAGAACCGAAUUUGUG------------------------------------------------------------- 1066 1,0 ---------------------------ACCCUGUAGAACCGAAUUUGUGa------------------------------------------------------------ 632 1,0 ---------------------------ACCCUGUAGAACCGAAUUUGUGaa----------------------------------------------------------- 10 1,0 ---------------------------ACCCUGUAGAACCGAAUUUGUGc------------------------------------------------------------ 2 1,0 ---------------------------ACCCUGUAGAACCGAAUUUGUGg------------------------------------------------------------ 3 1,0 ---------------------------ACCCUGUAGAACCGAAUUUGUGU------------------------------------------------------------ 767 1,1 ----------------------------CCCUGUAGAACCGAAUUUGU-------------------------------------------------------------- 15 2,-1 ----------------------------CCCUGUAGAACCGAAUUUGUuu------------------------------------------------------------ 2 2,-1 ----------------------------CCCUGUAGAACCGAAUUUGUG------------------------------------------------------------- 4 2,0 ----------------------------CCCUGUAGAACCGAAUUUGUGa------------------------------------------------------------ 4 2,0 ----------------------------CCCUGUAGAACCGAAUUUGUGU------------------------------------------------------------ 3 2,1 -----------------------------------------------------------------ACAGAUUCGAUUCUAGGGGAA------------------------ 4 0,-1 -----------------------------------------------------------------ACAGAUUCGAUUCUAGGGGAAU----------------------- 70 0,0 -----------------------------------------------------------------ACAGAUUCGAUUCUAGGGGAAUu---------------------- 2 0,0 ------------------------------------------------------------------CAGAUUCGAUUCUAGGGGAA------------------------ 2 1,-1 ------------------------------------------------------------------CAGAUUCGAUUCUAGGGGAAa----------------------- 4 1,-1 ------------------------------------------------------------------CAGAUUCGAUUCUAGGGGAAU----------------------- 132 1,0 ------------------------------------------------------------------CAGAUUCGAUUCUAGGGGAAUA---------------------- 2 1,1 -------------------------------------------------------------------AGAUUCGAUUCUAGGGGAAa----------------------- 2 2,-1 -------------------------------------------------------------------AGAUUCGAUUCUAGGGGAAU----------------------- 136 2,0 -------------------------------------------------------------------AGAUUCGAUUCUAGGGGAAUA---------------------- 6 2,1 -------------------------------------------------------------------AGAUUCGAUUCUAGGGGAAUAaa-------------------- 2 2,1 >hsa-mir-1179 5pM:15-35 Normal ggcuggaaaggaagAAGCAUUCUUUCAUUGGUUGGuguguauugccuugucaaccaauaagaggaugccauuuauccuuuucugacuagcu --------------AAGCAUUCUUUCAUUGGUUGGU------------------------------------------------------- 4 0,1 >hsa-mir-1180 3pM:41-62 Normal gcugcuggacccacccggccgggaauagugcuccugguugUUUCCGGCUCGCGUGGGUGUGUcggcggc ----------------------------------------UUUCCGGCUCGCGUGGGU----------- 2 0,-4 ----------------------------------------UUUCCGGCUCGCGUGGGUGU--------- 27 0,-2 ----------------------------------------UUUCCGGCUCGCGUGGGUGUGU------- 21 0,0 >hsa-mir-1185-1 5pM:15-35 Normal uuugguacuugaagAGAGGAUACCCUUUGUAUGUUcacuugauuaauggcgaauauacagggggagacucuuauuugcguaucaaa --------------AGAGGAUACCCUUUGUAUGUU--------------------------------------------------- 6 0,0 --------------AGAGGAUACCCUUUGUAUGUUC-------------------------------------------------- 74 0,1 ----------------------------------------------------AUAUACAGGGGGAGACUCUUA------------- 2 ----------------------------------------------------AUAUACAGGGGGAGACUCUUAU------------ 7 >hsa-mir-1185-2 5pM:15-35 Normal uuugguacuuaaagAGAGGAUACCCUUUGUAUGUUcacuugauuaauggcgaauauacagggggagacucucauuugcguaucaaa --------------AGAGGAUACCCUUUGUAUGUU--------------------------------------------------- 6 0,0 --------------AGAGGAUACCCUUUGUAUGUUC-------------------------------------------------- 74 0,1 >hsa-mir-122 MA:15-36;mi:51-72 Normal ccuuagcagagcugUGGAGUGUGACAAUGGUGUUUGugucuaaacuaucaAACGCCAUUAUCACACUAAAUAgcuacugcuaggc --------------UGGAGUGUGACAAUGGUGUUU-------------------------------------------------- 4 0,-1 --------------UGGAGUGUGACAAUGGUGUUUGa------------------------------------------------ 2 0,0 >hsa-mir-1226 mi:1-26;MA:54-75 Normal GUGAGGGCAUGCAGGCCUGGAUGGGGcagcugggaugguccaaaaggguggccUCACCAGCCCUGUGUUCCCUAG -----------------------------------------------------UCACCAGCCCUGUGUUCCCUAG 2 0,0 >hsa-mir-1227 3pM:69-88 Normal guggggccaggcgguggugggcacugcuggggugggcacagcagccaugcagagcgggcauuugacccCGUGCCACCCUUUUCCCCAG --------------------------------------------------------------------CGUGCCACCCUUUUCCCCAGa 2 0,0 --------------------------------------------------------------------CGUGCCACCCUUUUCCCCAGu 2 0,0 >hsa-mir-1228 mi:1-21;MA:52-71 Normal GUGGGCGGGGGCAGGUGUGUGgugggugguggccugcggugagcagggcccUCACACCUGCCUCGCCCCCCag ---------------------------------------------------UCACACCUGCCUCGCCCCCCA- 8 0,1 >hsa-mir-124-1 mi:14-35;MA:53-72 Normal aggccucucucucCGUGUUCACAGCGGACCUUGAUuuaaauguccauacaauUAAGGCACGCGGUGAAUGCCaagaauggggcug -------------CGUGUUCACAGCGGACCUUGA--------------------------------------------------- 12 0,-1 ---------------------------------------------------UUAAGGCACGCGGUGAAUGCCA------------ 4 -1,1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCA------------ 14 0,1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAA----------- 2 0,2 -----------------------------------------------------AAGGCACGCGGUGAAUGCCA------------ 4 1,1 ------------------------------------------------------AGGCACGCGGUGAAUGCCA------------ 2 2,1 >hsa-mir-124-2 mi:25-46;MA:62-81 Normal aucaagauuagaggcucugcucucCGUGUUCACAGCGGACCUUGAUuuaaugucauacaauUAAGGCACGCGGUGAAUGCCaagagcggagccuacggcugcacuugaa ------------------------CGUGUUCACAGCGGACCUUGA---------------------------------------------------------------- 12 0,-1 ------------------------------------------------------------UUAAGGCACGCGGUGAAUGCCA--------------------------- 4 -1,1 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCCA--------------------------- 14 0,1 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCCAA-------------------------- 2 0,2 --------------------------------------------------------------AAGGCACGCGGUGAAUGCCA--------------------------- 4 1,1 ---------------------------------------------------------------AGGCACGCGGUGAAUGCCA--------------------------- 2 2,1 >hsa-mir-124-3 mi:15-36;MA:53-72 Normal ugagggccccucugCGUGUUCACAGCGGACCUUGAUuuaaugucuauacaauUAAGGCACGCGGUGAAUGCCaagagaggcgccucc --------------CGUGUUCACAGCGGACCUUGA---------------------------------------------------- 12 0,-1 ---------------------------------------------------UUAAGGCACGCGGUGAAUGCCA-------------- 4 -1,1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCA-------------- 14 0,1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAA------------- 2 0,2 -----------------------------------------------------AAGGCACGCGGUGAAUGCCA-------------- 4 1,1 ------------------------------------------------------AGGCACGCGGUGAAUGCCA-------------- 2 2,1 >hsa-mir-1246 5pM:11-29 Normal uguauccuugAAUGGAUUUUUGGAGCAGGaguggacaccugacccaaaggaaaucaauccauaggcuagcaau ----------AAUGGAUUUUUGGAGCAGG-------------------------------------------- 5 0,0 -----------AUGGAUUUUUGGAGCAGG-------------------------------------------- 4 1,0 >hsa-mir-1247 5pM:40-61 Normal ccgcuugccucgcccagcgcagccccggccgcugggcgcACCCGUCCCGUUCGUCCCCGGAcguugcucucuaccccgggaacgucgagacuggagcgcccgaacugagccaccuucgcggaccccgagagcggcg ---------------------------------------ACCCGUCCCGUUCGUCCCCGG---------------------------------------------------------------------------- 7 0,-1 ---------------------------------------ACCCGUCCCGUUCGUCCCCGGc--------------------------------------------------------------------------- 2 0,-1 ---------------------------------------ACCCGUCCCGUUCGUCCCCGGu--------------------------------------------------------------------------- 4 0,-1 ---------------------------------------ACCCGUCCCGUUCGUCCCCGGA--------------------------------------------------------------------------- 96 0,0 ---------------------------------------ACCCGUCCCGUUCGUCCCCGGAa-------------------------------------------------------------------------- 26 0,0 ---------------------------------------ACCCGUCCCGUUCGUCCCCGGAau------------------------------------------------------------------------- 2 0,0 ---------------------------------------ACCCGUCCCGUUCGUCCCCGGAu-------------------------------------------------------------------------- 31 0,0 ---------------------------------------ACCCGUCCCGUUCGUCCCCGGAuu------------------------------------------------------------------------- 2 0,0 -----------------------------------------------------------------------------GGGAACGUCGAGACUGGAGC--------------------------------------- 2 >hsa-mir-1249 3pM:41-62 Normal gggaggagggaggagaugggccaaguucccucuggcuggaACGCCCUUCCCCCCCUUCUUCAccug ----------------------------------------ACGCCCUUCCCCCCCUUCU------- 2 0,-3 ----------------------------------------ACGCCCUUCCCCCCCUUCUU------ 6 0,-2 ----------------------------------------ACGCCCUUCCCCCCCUUCUUC----- 10 0,-1 ----------------------------------------ACGCCCUUCCCCCCCUUCUUCA---- 32 0,0 >hsa-mir-1254 5pM:18-41 Normal ggugggaggauugcuugAGCCUGGAAGCUGGAGCCUGCAGUgaacuaucauugugccacuguacuccagccuaggcaacaaaaugaaauccugucua -----------------AGCCUGGAAGCUGGAGCCUGCAG--------------------------------------------------------- 2 0,-1 -----------------AGCCUGGAAGCUGGAGCCUGCAGU-------------------------------------------------------- 2 0,0 >hsa-mir-1254-2 5pM:4-27 Normal cugAGCCUGGAAGCUGGAGCCUGCAGUgagcuaugaucaugucccuguacucuagccugggca ---AGCCUGGAAGCUGGAGCCUGCAG------------------------------------- 2 0,-1 ---AGCCUGGAAGCUGGAGCCUGCAGU------------------------------------ 2 0,0 >hsa-mir-1255b-1 5pM:3-24 Normal uaCGGAUGAGCAAAGAAAGUGGUUucuuaaaauggaaucuacucuuugugaagaugcugugaa --CGGAUGAGCAAAGAAAGUGGUU--------------------------------------- 2 0,0 >hsa-mir-1255b-2 5pM:6-27 Normal ucuuaCGGAUGAGCAAAGAAAGUGGUUugcgccucaagaaaccacuuucuuugcucauccauaagga -----CGGAUGAGCAAAGAAAGUGGUU---------------------------------------- 2 0,0 >hsa-mir-125a 5p:15-38;3p:53-74 Normal ugccagucucuaggUCCCUGAGACCCUUUAACCUGUGAggacauccagggucACAGGUGAGGUUCUUGGGAGCCuggcgucuggcc --------------UCCCUGAGACCCUUUAACC----------------------------------------------------- 41 0,-5 --------------UCCCUGAGACCCUUUAACCa---------------------------------------------------- 14 0,-5 --------------UCCCUGAGACCCUUUAACCU---------------------------------------------------- 213 0,-4 --------------UCCCUGAGACCCUUUAACCUa--------------------------------------------------- 4 0,-4 --------------UCCCUGAGACCCUUUAACCUau-------------------------------------------------- 28 0,-4 --------------UCCCUGAGACCCUUUAACCUu--------------------------------------------------- 7 0,-4 --------------UCCCUGAGACCCUUUAACCUuu-------------------------------------------------- 32 0,-4 --------------UCCCUGAGACCCUUUAACCUG--------------------------------------------------- 740 0,-3 --------------UCCCUGAGACCCUUUAACCUGa-------------------------------------------------- 317 0,-3 --------------UCCCUGAGACCCUUUAACCUGaa------------------------------------------------- 13 0,-3 --------------UCCCUGAGACCCUUUAACCUGc-------------------------------------------------- 30 0,-3 --------------UCCCUGAGACCCUUUAACCUGg-------------------------------------------------- 13 0,-3 --------------UCCCUGAGACCCUUUAACCUGU-------------------------------------------------- 13116 0,-2 --------------UCCCUGAGACCCUUUAACCUGUa------------------------------------------------- 66 0,-2 --------------UCCCUGAGACCCUUUAACCUGUu------------------------------------------------- 54 0,-2 --------------UCCCUGAGACCCUUUAACCUGUG------------------------------------------------- 4061 0,-1 --------------UCCCUGAGACCCUUUAACCUGUGc------------------------------------------------ 3 0,-1 --------------UCCCUGAGACCCUUUAACCUGUGg------------------------------------------------ 2 0,-1 --------------UCCCUGAGACCCUUUAACCUGUGu------------------------------------------------ 463 0,-1 --------------UCCCUGAGACCCUUUAACCUGUGA------------------------------------------------ 1286 0,0 --------------UCCCUGAGACCCUUUAACCUGUGAa----------------------------------------------- 10 0,0 --------------UCCCUGAGACCCUUUAACCUGUGAu----------------------------------------------- 6 0,0 ---------------CCCUGAGACCCUUUAACCUGU-------------------------------------------------- 48 1,-2 ---------------CCCUGAGACCCUUUAACCUGUG------------------------------------------------- 14 1,-1 ---------------CCCUGAGACCCUUUAACCUGUGu------------------------------------------------ 2 1,-1 ---------------CCCUGAGACCCUUUAACCUGUGA------------------------------------------------ 4 1,0 ----------------CCUGAGACCCUUUAACCU---------------------------------------------------- 2 2,-4 ----------------CCUGAGACCCUUUAACCUG--------------------------------------------------- 6 2,-3 ----------------CCUGAGACCCUUUAACCUGU-------------------------------------------------- 102 2,-2 ----------------CCUGAGACCCUUUAACCUGUG------------------------------------------------- 28 2,-1 ----------------CCUGAGACCCUUUAACCUGUGA------------------------------------------------ 2 2,0 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAa-------------- 3 0,-3 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAaa------------- 3 0,-3 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAG-------------- 6 0,-2 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAGa------------- 3 0,-2 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAGC------------- 50 0,-1 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAGCC------------ 10 0,0 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAGCCa----------- 3 0,0 -----------------------------------------------------CAGGUGAGGUUCUUGGGAGCC------------ 2 1,0 >hsa-mir-125b-1 MA:15-36;mi:55-76 Normal ugcgcuccucucagUCCCUGAGACCCUAACUUGUGAuguuuaccguuuaaauccACGGGUUAGGCUCUUGGGAGCUgcgagucgugcu --------------UCCCUGAGACCCUAACUU-------------------------------------------------------- 883 0,-4 --------------UCCCUGAGACCCUAACUUa------------------------------------------------------- 38 0,-4 --------------UCCCUGAGACCCUAACUUaa------------------------------------------------------ 10 0,-4 --------------UCCCUGAGACCCUAACUUau------------------------------------------------------ 24 0,-4 --------------UCCCUGAGACCCUAACUUu------------------------------------------------------- 12 0,-4 --------------UCCCUGAGACCCUAACUUuu------------------------------------------------------ 5 0,-4 --------------UCCCUGAGACCCUAACUUG------------------------------------------------------- 1081 0,-3 --------------UCCCUGAGACCCUAACUUGa------------------------------------------------------ 185 0,-3 --------------UCCCUGAGACCCUAACUUGaa----------------------------------------------------- 16 0,-3 --------------UCCCUGAGACCCUAACUUGc------------------------------------------------------ 23 0,-3 --------------UCCCUGAGACCCUAACUUGg------------------------------------------------------ 4 0,-3 --------------UCCCUGAGACCCUAACUUGU------------------------------------------------------ 7850 0,-2 --------------UCCCUGAGACCCUAACUUGUa----------------------------------------------------- 53 0,-2 --------------UCCCUGAGACCCUAACUUGUaa---------------------------------------------------- 221 0,-2 --------------UCCCUGAGACCCUAACUUGUau---------------------------------------------------- 5 0,-2 --------------UCCCUGAGACCCUAACUUGUc----------------------------------------------------- 8 0,-2 --------------UCCCUGAGACCCUAACUUGUu----------------------------------------------------- 30 0,-2 --------------UCCCUGAGACCCUAACUUGUuu---------------------------------------------------- 3 0,-2 --------------UCCCUGAGACCCUAACUUGUG----------------------------------------------------- 9959 0,-1 --------------UCCCUGAGACCCUAACUUGUGc---------------------------------------------------- 190 0,-1 --------------UCCCUGAGACCCUAACUUGUGg---------------------------------------------------- 127 0,-1 --------------UCCCUGAGACCCUAACUUGUGu---------------------------------------------------- 2294 0,-1 --------------UCCCUGAGACCCUAACUUGUGuu--------------------------------------------------- 7 0,-1 --------------UCCCUGAGACCCUAACUUGUGA---------------------------------------------------- 84459 0,0 --------------UCCCUGAGACCCUAACUUGUGAa--------------------------------------------------- 13672 0,0 --------------UCCCUGAGACCCUAACUUGUGAaa-------------------------------------------------- 1306 0,0 --------------UCCCUGAGACCCUAACUUGUGAau-------------------------------------------------- 100 0,0 --------------UCCCUGAGACCCUAACUUGUGAc--------------------------------------------------- 69 0,0 --------------UCCCUGAGACCCUAACUUGUGAU--------------------------------------------------- 391 0,1 --------------UCCCUGAGACCCUAACUUGUGAUc-------------------------------------------------- 4 0,1 ---------------CCCUGAGACCCUAACUUGU------------------------------------------------------ 10 1,-2 ---------------CCCUGAGACCCUAACUUGUG----------------------------------------------------- 39 1,-1 ---------------CCCUGAGACCCUAACUUGUGu---------------------------------------------------- 5 1,-1 ---------------CCCUGAGACCCUAACUUGUGA---------------------------------------------------- 289 1,0 ---------------CCCUGAGACCCUAACUUGUGAa--------------------------------------------------- 48 1,0 ---------------CCCUGAGACCCUAACUUGUGAaa-------------------------------------------------- 11 1,0 ----------------CCUGAGACCCUAACUUGU------------------------------------------------------ 49 2,-2 ----------------CCUGAGACCCUAACUUGUG----------------------------------------------------- 77 2,-1 ----------------CCUGAGACCCUAACUUGUGu---------------------------------------------------- 10 2,-1 ----------------CCUGAGACCCUAACUUGUGA---------------------------------------------------- 647 2,0 ----------------CCUGAGACCCUAACUUGUGAa--------------------------------------------------- 98 2,0 ----------------CCUGAGACCCUAACUUGUGAaa-------------------------------------------------- 5 2,0 -----------------------------------------------------CACGGGUUAGGCUCUUGGGAGu------------- 2 -1,-2 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAaa------------- 4 0,-3 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAG-------------- 24 0,-2 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGa------------- 7 0,-2 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGu------------- 51 0,-2 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGC------------- 51 0,-1 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGCa------------ 2 0,-1 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGCU------------ 124 0,0 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGCUa----------- 5 0,0 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGCUu----------- 20 0,0 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGCUuu---------- 7 0,0 >hsa-mir-125b-2 MA:17-38;mi:54-75 Normal accagacuuuuccuagUCCCUGAGACCCUAACUUGUGAgguauuuuaguaacaUCACAAGUCAGGCUCUUGGGACcuaggcggagggga ----------------UCCCUGAGACCCUAACUU------------------------------------------------------- 883 0,-4 ----------------UCCCUGAGACCCUAACUUa------------------------------------------------------ 38 0,-4 ----------------UCCCUGAGACCCUAACUUaa----------------------------------------------------- 10 0,-4 ----------------UCCCUGAGACCCUAACUUau----------------------------------------------------- 24 0,-4 ----------------UCCCUGAGACCCUAACUUu------------------------------------------------------ 12 0,-4 ----------------UCCCUGAGACCCUAACUUuu----------------------------------------------------- 5 0,-4 ----------------UCCCUGAGACCCUAACUUG------------------------------------------------------ 1081 0,-3 ----------------UCCCUGAGACCCUAACUUGa----------------------------------------------------- 185 0,-3 ----------------UCCCUGAGACCCUAACUUGaa---------------------------------------------------- 16 0,-3 ----------------UCCCUGAGACCCUAACUUGc----------------------------------------------------- 23 0,-3 ----------------UCCCUGAGACCCUAACUUGg----------------------------------------------------- 4 0,-3 ----------------UCCCUGAGACCCUAACUUGU----------------------------------------------------- 7850 0,-2 ----------------UCCCUGAGACCCUAACUUGUa---------------------------------------------------- 53 0,-2 ----------------UCCCUGAGACCCUAACUUGUaa--------------------------------------------------- 221 0,-2 ----------------UCCCUGAGACCCUAACUUGUau--------------------------------------------------- 5 0,-2 ----------------UCCCUGAGACCCUAACUUGUc---------------------------------------------------- 8 0,-2 ----------------UCCCUGAGACCCUAACUUGUu---------------------------------------------------- 30 0,-2 ----------------UCCCUGAGACCCUAACUUGUuu--------------------------------------------------- 3 0,-2 ----------------UCCCUGAGACCCUAACUUGUG---------------------------------------------------- 9959 0,-1 ----------------UCCCUGAGACCCUAACUUGUGc--------------------------------------------------- 190 0,-1 ----------------UCCCUGAGACCCUAACUUGUGg--------------------------------------------------- 127 0,-1 ----------------UCCCUGAGACCCUAACUUGUGu--------------------------------------------------- 2294 0,-1 ----------------UCCCUGAGACCCUAACUUGUGuu-------------------------------------------------- 7 0,-1 ----------------UCCCUGAGACCCUAACUUGUGA--------------------------------------------------- 84459 0,0 ----------------UCCCUGAGACCCUAACUUGUGAa-------------------------------------------------- 13672 0,0 ----------------UCCCUGAGACCCUAACUUGUGAaa------------------------------------------------- 1306 0,0 ----------------UCCCUGAGACCCUAACUUGUGAau------------------------------------------------- 100 0,0 ----------------UCCCUGAGACCCUAACUUGUGAc-------------------------------------------------- 69 0,0 ----------------UCCCUGAGACCCUAACUUGUGAG-------------------------------------------------- 170 0,1 ----------------UCCCUGAGACCCUAACUUGUGAGa------------------------------------------------- 20 0,1 ----------------UCCCUGAGACCCUAACUUGUGAGu------------------------------------------------- 7 0,1 -----------------CCCUGAGACCCUAACUUGU----------------------------------------------------- 10 1,-2 -----------------CCCUGAGACCCUAACUUGUG---------------------------------------------------- 39 1,-1 -----------------CCCUGAGACCCUAACUUGUGu--------------------------------------------------- 5 1,-1 -----------------CCCUGAGACCCUAACUUGUGA--------------------------------------------------- 289 1,0 -----------------CCCUGAGACCCUAACUUGUGAa-------------------------------------------------- 48 1,0 -----------------CCCUGAGACCCUAACUUGUGAaa------------------------------------------------- 11 1,0 ------------------CCUGAGACCCUAACUUGU----------------------------------------------------- 49 2,-2 ------------------CCUGAGACCCUAACUUGUG---------------------------------------------------- 77 2,-1 ------------------CCUGAGACCCUAACUUGUGu--------------------------------------------------- 10 2,-1 ------------------CCUGAGACCCUAACUUGUGA--------------------------------------------------- 647 2,0 ------------------CCUGAGACCCUAACUUGUGAa-------------------------------------------------- 98 2,0 ------------------CCUGAGACCCUAACUUGUGAaa------------------------------------------------- 5 2,0 ----------------------------------------------------AUCACAAGUCAGGCUCUUGGGA--------------- 62 -1,-1 ----------------------------------------------------AUCACAAGUCAGGCUCUUGGGAa-------------- 11 -1,-1 ----------------------------------------------------AUCACAAGUCAGGCUCUUGGGAu-------------- 10 -1,-1 ----------------------------------------------------AUCACAAGUCAGGCUCUUGGGAC-------------- 24 -1,0 ----------------------------------------------------AUCACAAGUCAGGCUCUUGGGACu------------- 4 -1,0 -----------------------------------------------------UCACAAGUCAGGCUCUUGG----------------- 2 0,-3 -----------------------------------------------------UCACAAGUCAGGCUCUUGGGA--------------- 2 0,-1 -----------------------------------------------------UCACAAGUCAGGCUCUUGGGAa-------------- 8 0,-1 -----------------------------------------------------UCACAAGUCAGGCUCUUGGGAC-------------- 20 0,0 -----------------------------------------------------UCACAAGUCAGGCUCUUGGGACa------------- 2 0,0 -----------------------------------------------------UCACAAGUCAGGCUCUUGGGACu------------- 8 0,0 -------------------------------------------------------ACAAGUCAGGCUCUUGGGA--------------- 19 2,-1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGAa-------------- 9 2,-1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGAaa------------- 9 2,-1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGAu-------------- 5 2,-1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGAuu------------- 2 2,-1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGAC-------------- 94 2,0 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACa------------- 41 2,0 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACaa------------ 5 2,0 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACu------------- 76 2,0 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACuu------------ 6 2,0 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACC------------- 158 2,1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCa------------ 4 2,1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCau----------- 4 2,1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCU------------ 329 2,2 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCUu----------- 85 2,2 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCUuu---------- 61 2,2 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCUA----------- 14 2,3 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCUAa---------- 2 2,3 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCUAau--------- 2 2,3 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCUAu---------- 15 2,3 >hsa-mir-126 mi:15-35;MA:52-73 Normal cgcuggcgacgggaCAUUAUUACUUUUGGUACGCGcugugacacuucaaacUCGUACCGUGAGUAAUAAUGCGccguccacggca --------------CAUUAUUACUUUUGGUAC----------------------------------------------------- 198 0,-3 --------------CAUUAUUACUUUUGGUACu---------------------------------------------------- 5 0,-3 --------------CAUUAUUACUUUUGGUACG---------------------------------------------------- 254 0,-2 --------------CAUUAUUACUUUUGGUACGa--------------------------------------------------- 17 0,-2 --------------CAUUAUUACUUUUGGUACGaa-------------------------------------------------- 2 0,-2 --------------CAUUAUUACUUUUGGUACGC--------------------------------------------------- 355 0,-1 --------------CAUUAUUACUUUUGGUACGCa-------------------------------------------------- 35 0,-1 --------------CAUUAUUACUUUUGGUACGCaa------------------------------------------------- 5 0,-1 --------------CAUUAUUACUUUUGGUACGCau------------------------------------------------- 2 0,-1 --------------CAUUAUUACUUUUGGUACGCu-------------------------------------------------- 51 0,-1 --------------CAUUAUUACUUUUGGUACGCuu------------------------------------------------- 3 0,-1 --------------CAUUAUUACUUUUGGUACGCG-------------------------------------------------- 3901 0,0 --------------CAUUAUUACUUUUGGUACGCGa------------------------------------------------- 1019 0,0 --------------CAUUAUUACUUUUGGUACGCGaa------------------------------------------------ 29 0,0 --------------CAUUAUUACUUUUGGUACGCGau------------------------------------------------ 4 0,0 --------------CAUUAUUACUUUUGGUACGCGg------------------------------------------------- 6 0,0 --------------CAUUAUUACUUUUGGUACGCGu------------------------------------------------- 296 0,0 --------------CAUUAUUACUUUUGGUACGCGC------------------------------------------------- 42 0,1 --------------CAUUAUUACUUUUGGUACGCGCU------------------------------------------------ 12 0,2 ---------------AUUAUUACUUUUGGUACG---------------------------------------------------- 4 1,-2 ---------------AUUAUUACUUUUGGUACGC--------------------------------------------------- 9 1,-1 ---------------AUUAUUACUUUUGGUACGCa-------------------------------------------------- 3 1,-1 ---------------AUUAUUACUUUUGGUACGCG-------------------------------------------------- 160 1,0 ---------------AUUAUUACUUUUGGUACGCGa------------------------------------------------- 23 1,0 ---------------AUUAUUACUUUUGGUACGCGu------------------------------------------------- 7 1,0 ---------------AUUAUUACUUUUGGUACGCGC------------------------------------------------- 4 1,1 ---------------AUUAUUACUUUUGGUACGCGCU------------------------------------------------ 18 1,2 --------------------------------------------------CUCGUACCGUGAGUAAUAAa--------------- 2 -1,-4 --------------------------------------------------CUCGUACCGUGAGUAAUAAU--------------- 17 -1,-3 --------------------------------------------------CUCGUACCGUGAGUAAUAAUG-------------- 46 -1,-2 --------------------------------------------------CUCGUACCGUGAGUAAUAAUGa------------- 22 -1,-2 --------------------------------------------------CUCGUACCGUGAGUAAUAAUGu------------- 2 -1,-2 --------------------------------------------------CUCGUACCGUGAGUAAUAAUGC------------- 79 -1,-1 --------------------------------------------------CUCGUACCGUGAGUAAUAAUGCG------------ 178 -1,0 --------------------------------------------------CUCGUACCGUGAGUAAUAAUGCGa----------- 4 -1,0 ---------------------------------------------------UCGUACCGUGAGUAAUAA---------------- 58 0,-4 ---------------------------------------------------UCGUACCGUGAGUAAUAAa--------------- 11 0,-4 ---------------------------------------------------UCGUACCGUGAGUAAUAAaa-------------- 10 0,-4 ---------------------------------------------------UCGUACCGUGAGUAAUAAU--------------- 178 0,-3 ---------------------------------------------------UCGUACCGUGAGUAAUAAUa-------------- 7 0,-3 ---------------------------------------------------UCGUACCGUGAGUAAUAAUu-------------- 2 0,-3 ---------------------------------------------------UCGUACCGUGAGUAAUAAUG-------------- 512 0,-2 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGa------------- 305 0,-2 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGaa------------ 60 0,-2 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGu------------- 27 0,-2 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGC------------- 973 0,-1 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCa------------ 187 0,-1 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCaa----------- 32 0,-1 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCc------------ 4 0,-1 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCu------------ 52 0,-1 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCG------------ 10351 0,0 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCGa----------- 1938 0,0 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCGau---------- 3 0,0 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCGu----------- 338 0,0 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCGC----------- 4 0,1 ----------------------------------------------------CGUACCGUGAGUAAUAAU--------------- 73 1,-3 ----------------------------------------------------CGUACCGUGAGUAAUAAUa-------------- 2 1,-3 ----------------------------------------------------CGUACCGUGAGUAAUAAUaa------------- 2 1,-3 ----------------------------------------------------CGUACCGUGAGUAAUAAUG-------------- 175 1,-2 ----------------------------------------------------CGUACCGUGAGUAAUAAUGa------------- 99 1,-2 ----------------------------------------------------CGUACCGUGAGUAAUAAUGaa------------ 37 1,-2 ----------------------------------------------------CGUACCGUGAGUAAUAAUGu------------- 3 1,-2 ----------------------------------------------------CGUACCGUGAGUAAUAAUGC------------- 236 1,-1 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCa------------ 67 1,-1 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCaa----------- 46 1,-1 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCc------------ 2 1,-1 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCu------------ 30 1,-1 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCG------------ 5863 1,0 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCGa----------- 1941 1,0 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCGaa---------- 25 1,0 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCGg----------- 10 1,0 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCGu----------- 1734 1,0 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCGuu---------- 3 1,0 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCGC----------- 11 1,1 -----------------------------------------------------GUACCGUGAGUAAUAAUG-------------- 10 2,-2 -----------------------------------------------------GUACCGUGAGUAAUAAUGaa------------ 2 2,-2 -----------------------------------------------------GUACCGUGAGUAAUAAUGC------------- 4 2,-1 -----------------------------------------------------GUACCGUGAGUAAUAAUGCaa----------- 2 2,-1 -----------------------------------------------------GUACCGUGAGUAAUAAUGCG------------ 366 2,0 -----------------------------------------------------GUACCGUGAGUAAUAAUGCGa----------- 110 2,0 -----------------------------------------------------GUACCGUGAGUAAUAAUGCGu----------- 73 2,0 >hsa-mir-1260b 5pM:10-28 Normal ucuccguuuAUCCCACCACUGCCACCAUuauugcuacuguucagcaggugcugcugguggugauggugauagucuggugggggcggugg ---------AUCCCACCACUGCCACCA-------------------------------------------------------------- 29 0,-1 ---------AUCCCACCACUGCCACCAa------------------------------------------------------------- 2 0,-1 ---------AUCCCACCACUGCCACCAaa------------------------------------------------------------ 9 0,-1 ---------AUCCCACCACUGCCACCAau------------------------------------------------------------ 4 0,-1 ---------AUCCCACCACUGCCACCAU------------------------------------------------------------- 4 0,0 >hsa-mir-1262 5pM:14-35 Normal aucuacaauggugAUGGGUGAAUUUGUAGAAGGAUgaaagucaaagaauccuucugggaacuaauuuuuggccuucaacaagaauugugauau -------------AUGGGUGAAUUUGUAGAAGGAU---------------------------------------------------------- 2 0,0 >hsa-mir-1268 5pM:5-22 Normal uagcCGGGCGUGGUGGUGGGGGccuguggucccagcuacuuuggaggcugag ----CGGGCGUGGUGGUGGGGG------------------------------ 53 0,0 >hsa-mir-1268b 5pM:4-23 Normal accCGGGCGUGGUGGUGGGGGUGggugccuguaauuccagcuaguuggga ---CGGGCGUGGUGGUGGGGG----------------------------- 53 0,-2 >hsa-mir-127 5p:23-44;3p:57-78 Normal ugugaucacugucuccagccugCUGAAGCUCAGAGGGCUCUGAUucagaaagaucaUCGGAUCCGUCUGAGCUUGGCUggucggaagucucaucauc --------------------UGCUGAAGCUCAGAGGGCUCUGAU----------------------------------------------------- 2 -2,0 ---------------------GCUGAAGCUCAGAGGGCUCUGAU----------------------------------------------------- 2 -1,0 ----------------------CUGAAGCUCAGAGGGCUCUGA------------------------------------------------------ 129 0,-1 ----------------------CUGAAGCUCAGAGGGCUCUGAa----------------------------------------------------- 16 0,-1 ----------------------CUGAAGCUCAGAGGGCUCUGAaa---------------------------------------------------- 10 0,-1 ----------------------CUGAAGCUCAGAGGGCUCUGAau---------------------------------------------------- 5 0,-1 ----------------------CUGAAGCUCAGAGGGCUCUGAU----------------------------------------------------- 512 0,0 ----------------------CUGAAGCUCAGAGGGCUCUGAUa---------------------------------------------------- 13 0,0 ----------------------CUGAAGCUCAGAGGGCUCUGAUc---------------------------------------------------- 2 0,0 ----------------------CUGAAGCUCAGAGGGCUCUGAUU---------------------------------------------------- 362 0,1 ----------------------CUGAAGCUCAGAGGGCUCUGAUUu--------------------------------------------------- 17 0,1 -----------------------UGAAGCUCAGAGGGCUCUGA------------------------------------------------------ 9 1,-1 -----------------------UGAAGCUCAGAGGGCUCUGAU----------------------------------------------------- 88 1,0 -----------------------UGAAGCUCAGAGGGCUCUGAUa---------------------------------------------------- 2 1,0 -----------------------UGAAGCUCAGAGGGCUCUGAUU---------------------------------------------------- 148 1,1 -----------------------UGAAGCUCAGAGGGCUCUGAUUu--------------------------------------------------- 3 1,1 ------------------------GAAGCUCAGAGGGCUCUGAU----------------------------------------------------- 13 2,0 ------------------------GAAGCUCAGAGGGCUCUGAUU---------------------------------------------------- 101 2,1 ------------------------GAAGCUCAGAGGGCUCUGAUUC--------------------------------------------------- 26 2,2 ------------------------GAAGCUCAGAGGGCUCUGAUUCA-------------------------------------------------- 5 2,3 -------------------------------------------------------AUCGGAUCCGUCUGAGCUUGG--------------------- 8 -1,-2 -------------------------------------------------------AUCGGAUCCGUCUGAGCUUGGa-------------------- 5 -1,-2 -------------------------------------------------------AUCGGAUCCGUCUGAGCUUGGu-------------------- 48 -1,-2 --------------------------------------------------------UCGGAUCCGUCUGAGCUU----------------------- 31 0,-4 --------------------------------------------------------UCGGAUCCGUCUGAGCUUG---------------------- 30 0,-3 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGa--------------------- 4 0,-3 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGaa-------------------- 2 0,-3 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGG--------------------- 287 0,-2 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGa-------------------- 46 0,-2 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGaa------------------- 27 0,-2 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGau------------------- 7 0,-2 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGu-------------------- 33 0,-2 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGuu------------------- 12 0,-2 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGC-------------------- 540 0,-1 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCa------------------- 272 0,-1 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCaa------------------ 107 0,-1 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCau------------------ 119 0,-1 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCc------------------- 2 0,-1 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCg------------------- 5 0,-1 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCU------------------- 3098 0,0 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCUa------------------ 165 0,0 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCUaa----------------- 14 0,0 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCUau----------------- 56 0,0 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCUc------------------ 2 0,0 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCUu------------------ 452 0,0 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCUuu----------------- 101 0,0 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCUG------------------ 4 0,1 ---------------------------------------------------------CGGAUCCGUCUGAGCUUGG--------------------- 3 1,-2 ---------------------------------------------------------CGGAUCCGUCUGAGCUUGGC-------------------- 22 1,-1 ---------------------------------------------------------CGGAUCCGUCUGAGCUUGGCau------------------ 2 1,-1 ---------------------------------------------------------CGGAUCCGUCUGAGCUUGGCU------------------- 89 1,0 ---------------------------------------------------------CGGAUCCGUCUGAGCUUGGCUa------------------ 2 1,0 ---------------------------------------------------------CGGAUCCGUCUGAGCUUGGCUu------------------ 13 1,0 ----------------------------------------------------------GGAUCCGUCUGAGCUUGGCU------------------- 6 2,0 ----------------------------------------------------------GGAUCCGUCUGAGCUUGGCUaa----------------- 2 2,0 >hsa-mir-1270-1 5pM:13-35 Normal cacagaguuauaCUGGAGAUAUGGAAGAGCUGUGUuggguauaaguaacaggcuuuucuuuaucuucuauguggcucuuugca -----------ACUGGAGAUAUGGAAGAGCUGU-------------------------------------------------- 2 -1,-2 ------------CUGGAGAUAUGGAAGAGCUGUGU------------------------------------------------ 6 0,0 >hsa-mir-1270-2 5pM:13-35 Normal cacagaguuauaCUGGAGAUAUGGAAGAGCUGUGUuggguauaaguaacaggcuuuucuuuaucuucuauguggcucuuugca -----------ACUGGAGAUAUGGAAGAGCUGU-------------------------------------------------- 2 -1,-2 ------------CUGGAGAUAUGGAAGAGCUGUGU------------------------------------------------ 6 0,0 >hsa-mir-1271 5pM:15-36 Normal cacccagaucagugCUUGGCACCUAGCAAGCACUCAguaaauauuuguugagugccugcuaugugccaggcauugugcugagggcu --------------CUUGGCACCUAGCAAGCAC----------------------------------------------------- 2 0,-3 --------------CUUGGCACCUAGCAAGCACU---------------------------------------------------- 15 0,-2 --------------CUUGGCACCUAGCAAGCACUC--------------------------------------------------- 16 0,-1 --------------CUUGGCACCUAGCAAGCACUCA-------------------------------------------------- 41 0,0 --------------CUUGGCACCUAGCAAGCACUCAa------------------------------------------------- 6 0,0 --------------CUUGGCACCUAGCAAGCACUCAu------------------------------------------------- 2 0,0 >hsa-mir-1273c 5pM:10-31 Normal ugcagccugGGCGACAAAACGAGACCCUGUCuuuuuuuuuuucugagacagagucucguucuguugcccaagcugga ------------------------------------------------CAGAGUCUCGUUCUGUUGCCCAAa----- 2 >hsa-mir-1275 5pM:18-34 Normal ccucugugagaaaggguGUGGGGGAGAGGCUGUCuugugucuguaaguaugccaaacuuauuuuccccaaggcagaggga ---------------GUGUGGGGGAGAGGCUGU----------------------------------------------- 2 -2,-1 >hsa-mir-1277 3pM:47-68 Normal accucccaaauauauauauauauguacguauguguauauaaauguaUACGUAGAUAUAUAUGUAUUUUugguggguuu ----------UAUAUAUAUAUAUGUACGUAU----------------------------------------------- 5 ----------UAUAUAUAUAUAUGUACGUAUG---------------------------------------------- 2 ----------UAUAUAUAUAUAUGUACGUAUGa--------------------------------------------- 2 ----------------------------------------------UACGUAGAUAUAUAUGUAUUU----------- 2 0,-1 ----------------------------------------------UACGUAGAUAUAUAUGUAUUUU---------- 3 0,0 >hsa-mir-128-1 3pM:50-70 Normal ugagcuguuggauucggggccguagcacugucugagagguuuacauuucUCACAGUGAACCGGUCUCUUUuucagcugcuuc -------------------------------------------------UCACAGUGAACCGGUCUCU-------------- 7 0,-2 -------------------------------------------------UCACAGUGAACCGGUCUCUU------------- 22 0,-1 -------------------------------------------------UCACAGUGAACCGGUCUCUUaa----------- 2 0,-1 -------------------------------------------------UCACAGUGAACCGGUCUCUUU------------ 126 0,0 -------------------------------------------------UCACAGUGAACCGGUCUCUUUa----------- 15 0,0 -------------------------------------------------UCACAGUGAACCGGUCUCUUUaa---------- 3 0,0 -------------------------------------------------UCACAGUGAACCGGUCUCUUUU----------- 36 0,1 -------------------------------------------------UCACAGUGAACCGGUCUCUUUUU---------- 2 0,2 >hsa-mir-128-2 3pM:52-72 Normal ugugcagugggaaggggggccgauacacuguacgagagugaguagcaggucUCACAGUGAACCGGUCUCUUUcccuacuguguc ---------------------------------------------------UCACAGUGAACCGGUCUCU-------------- 7 0,-2 ---------------------------------------------------UCACAGUGAACCGGUCUCUU------------- 22 0,-1 ---------------------------------------------------UCACAGUGAACCGGUCUCUUaa----------- 2 0,-1 ---------------------------------------------------UCACAGUGAACCGGUCUCUUU------------ 126 0,0 ---------------------------------------------------UCACAGUGAACCGGUCUCUUUa----------- 15 0,0 ---------------------------------------------------UCACAGUGAACCGGUCUCUUUaa---------- 3 0,0 >hsa-mir-1285-1 3pM:51-72 Normal uguagagauaggaucucacuuuguugcccaggcuggucucaaacuccuggUCUGGGCAACAAAGUGAGACCUuaucucuacaag --------------------------------------------------UCUGGGCAACAAAGUGAGA--------------- 4 0,-3 --------------------------------------------------UCUGGGCAACAAAGUGAGAC-------------- 3 0,-2 --------------------------------------------------UCUGGGCAACAAAGUGAGACC------------- 3 0,-1 --------------------------------------------------UCUGGGCAACAAAGUGAGACCU------------ 2 0,0 >hsa-mir-1285-2 3pM:52-73 Normal uuugggaggccgaggcuggugcaucacuugagcccagcaauuugagaccaaUCUGGGCAACAAAGUGAGACCUccgucucuacaaaga ---------------------------------------------------UCUGGGCAACAAAGUGAGA------------------ 4 0,-3 ---------------------------------------------------UCUGGGCAACAAAGUGAGAC----------------- 3 0,-2 ---------------------------------------------------UCUGGGCAACAAAGUGAGACC---------------- 3 0,-1 ---------------------------------------------------UCUGGGCAACAAAGUGAGACCU--------------- 2 0,0 >hsa-mir-1287 5pM:16-37 Normal guugugcuguccaggUGCUGGAUCAGUGGUUCGAGUCugagccuuuaaaagccacucuagccacagaugcagugauuggagccaugacaa ---------------UGCUGGAUCAGUGGUUCGAG------------------------------------------------------- 2 0,-2 ---------------UGCUGGAUCAGUGGUUCGAGU------------------------------------------------------ 28 0,-1 ---------------UGCUGGAUCAGUGGUUCGAGUC----------------------------------------------------- 11 0,0 ---------------UGCUGGAUCAGUGGUUCGAGUCa---------------------------------------------------- 5 0,0 ------------------------------------------------------CUCUAGCCACAGAUGCAGUGA--------------- 2 ------------------------------------------------------CUCUAGCCACAGAUGCAGUGAU-------------- 4 >hsa-mir-129-2 5p:15-35;3p:57-78 Normal ugcccuucgcgaauCUUUUUGCGGUCUGGGCUUGCuguacauaacucaauagccggAAGCCCUUACCCCAAAAAGCAUuugcggagggcg --------------CUUUUUGCGGUCUGGGCUUGC------------------------------------------------------- 14 0,0 --------------------------------------------------------AAGCCCUUACCCCAAAAAGC-------------- 9 0,-2 --------------------------------------------------------AAGCCCUUACCCCAAAAAGCA------------- 17 0,-1 --------------------------------------------------------AAGCCCUUACCCCAAAAAGCAU------------ 44 0,0 >hsa-mir-1292 5pM:3-27 Normal ccUGGGAACGGGUUCCGGCAGACGCUGagguugcguugacgcucgcgccccggcucccguuccagg --UGGGAACGGGUUCCGGCAGACG------------------------------------------ 2 0,-3 --UGGGAACGGGUUCCGGCAGACGCU---------------------------------------- 2 0,-1 >hsa-mir-1296 5pM:16-37 Normal accuaccuaacugggUUAGGGCCCUGGCUCCAUCUCCuuuaggaaaaccuucuguggggaguggggcuucgacccuaacccaggugggcugu ---------------UUAGGGCCCUGGCUCCAUCUCa------------------------------------------------------- 2 0,-1 ---------------UUAGGGCCCUGGCUCCAUCUCC------------------------------------------------------- 2 0,0 -----------------------------------------------------------AGUGGGGCUUCGACCCUAAuu------------ 2 -----------------------------------------------------------AGUGGGGCUUCGACCCUAACC------------ 7 >hsa-mir-1299 3pM:62-83 Normal ccucauggcaguguucuggaauccuacgugagggacaaucauucagacccacguagcagugUUCUGGAAUUCUGUGUGAGGGA -------------------------------------------------------------UUCUGGAAUUCUGUGUGAG--- 2 0,-3 -------------------------------------------------------------UUCUGGAAUUCUGUGUGAGa-- 2 0,-3 -------------------------------------------------------------UUCUGGAAUUCUGUGUGAGG-- 6 0,-2 -------------------------------------------------------------UUCUGGAAUUCUGUGUGAGGa- 2 0,-2 -------------------------------------------------------------UUCUGGAAUUCUGUGUGAGGaa 7 0,-2 -------------------------------------------------------------UUCUGGAAUUCUGUGUGAGGau 2 0,-2 -------------------------------------------------------------UUCUGGAAUUCUGUGUGAGGGA 30 0,0 -------------------------------------------------------------UUCUGGAAUUCUGUGUGAGGGAa 4 0,0 >hsa-mir-1301 3pM:48-71 Normal ggauuguggggggucgcucuaggcaccgcagcacugugcuggggaugUUGCAGCUGCCUGGGAGUGACUUCacacaguccuc -----------------------------------------------UUGCAGCUGCCUGGGAGUGAC-------------- 14 0,-3 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACU------------- 3 0,-2 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACUU------------ 4 0,-1 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACUUu----------- 2 0,-1 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACUUC----------- 4 0,0 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACUUCu---------- 2 0,0 ------------------------------------------------UGCAGCUGCCUGGGAGUGACUU------------ 2 1,-1 >hsa-mir-1303 3pM:52-73 Normal ggcugggcaacauagcgagaccucaacucuacaauuuuuuuuuuuuuaaauUUUAGAGACGGGGUCUUGCUCUguugccaggcuuu --------------------------------------------------UUUUAGAGACGGGGUCUUGCUCU------------- 3 -1,0 ---------------------------------------------------UUUAGAGACGGGGUCUUGCUCU------------- 2 0,0 >hsa-mir-1306 3pM:55-72 Normal gugagcagucuccaccaccuccccugcaaacguccaguggugcagagguaauggACGUUGGCUCUGGUGGUGauggacaguccga --------------CCACCUCCCCUGCAAACGUC--------------------------------------------------- 2 --------------CCACCUCCCCUGCAAACGUCC-------------------------------------------------- 5 --------------CCACCUCCCCUGCAAACGUCCA------------------------------------------------- 8 ------------------------------------------------------ACGUUGGCUCUGGUGGUGAUG---------- 2 0,3 ------------------------------------------------------ACGUUGGCUCUGGUGGUGAUGu--------- 2 0,3 >hsa-mir-1307 3pM:80-101 Normal caucaagacccagcugagucacugucacugccuaccaaucucgaccggaccucgaccggcucgucuguguugccaaucgACUCGGCGUGGCGUCGGUCGUGguagauaggcggucaugcauacgaauuuucagcucuuguucuggugac ----------------------------------------UCGACCGGACCUCGACCG------------------------------------------------------------------------------------------- 5 ----------------------------------------UCGACCGGACCUCGACCGG------------------------------------------------------------------------------------------ 2 ----------------------------------------UCGACCGGACCUCGACCGGa----------------------------------------------------------------------------------------- 4 ----------------------------------------UCGACCGGACCUCGACCGGC----------------------------------------------------------------------------------------- 32 ----------------------------------------UCGACCGGACCUCGACCGGCa---------------------------------------------------------------------------------------- 5 ----------------------------------------UCGACCGGACCUCGACCGGCaa--------------------------------------------------------------------------------------- 2 ----------------------------------------UCGACCGGACCUCGACCGGCU---------------------------------------------------------------------------------------- 418 ----------------------------------------UCGACCGGACCUCGACCGGCUa--------------------------------------------------------------------------------------- 7 ----------------------------------------UCGACCGGACCUCGACCGGCUaa-------------------------------------------------------------------------------------- 2 ----------------------------------------UCGACCGGACCUCGACCGGCUau-------------------------------------------------------------------------------------- 2 ----------------------------------------UCGACCGGACCUCGACCGGCUu--------------------------------------------------------------------------------------- 5 ----------------------------------------UCGACCGGACCUCGACCGGCUC--------------------------------------------------------------------------------------- 80 ----------------------------------------UCGACCGGACCUCGACCGGCUCa-------------------------------------------------------------------------------------- 7 ----------------------------------------UCGACCGGACCUCGACCGGCUCc-------------------------------------------------------------------------------------- 2 ----------------------------------------UCGACCGGACCUCGACCGGCUCu-------------------------------------------------------------------------------------- 14 ----------------------------------------UCGACCGGACCUCGACCGGCUCG-------------------------------------------------------------------------------------- 194 ----------------------------------------UCGACCGGACCUCGACCGGCUCGa------------------------------------------------------------------------------------- 9 ----------------------------------------UCGACCGGACCUCGACCGGCUCGU------------------------------------------------------------------------------------- 3 -----------------------------------------CGACCGGACCUCGACCGGCU---------------------------------------------------------------------------------------- 12 ------------------------------------------GACCGGACCUCGACCGGCUC--------------------------------------------------------------------------------------- 2 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCG-------------------------------------------------- 9 0,-2 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGU------------------------------------------------- 18 0,-1 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUu------------------------------------------------ 7 0,-1 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUG------------------------------------------------ 29 0,0 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUGa----------------------------------------------- 13 0,0 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUGu----------------------------------------------- 42 0,0 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUGG----------------------------------------------- 166 0,1 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUGGa---------------------------------------------- 21 0,1 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUGGU---------------------------------------------- 25 0,2 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGU------------------------------------------------- 4 1,-1 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUG------------------------------------------------ 2 1,0 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUGu----------------------------------------------- 5 1,0 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUGG----------------------------------------------- 41 1,1 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUGGa---------------------------------------------- 6 1,1 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUGGau--------------------------------------------- 3 1,1 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUGGU---------------------------------------------- 10 1,2 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUGGUu--------------------------------------------- 5 1,2 >hsa-mir-130a mi:21-42;MA:55-76 Normal ugcugcuggccagagcucuuUUCACAUUGUGCUACUGUCUGCaccugucacuagCAGUGCAAUGUUAAAAGGGCAUuggccguguagug -----------------------------------------------------GCAGUGCAAUGUUAAAAGGGCAU------------- 7 -1,0 ------------------------------------------------------CAGUGCAAUGUUAAAAGG----------------- 35 0,-4 ------------------------------------------------------CAGUGCAAUGUUAAAAGGG---------------- 58 0,-3 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGa--------------- 27 0,-3 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGaa-------------- 9 0,-3 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGu--------------- 3 0,-3 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGC--------------- 140 0,-2 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCA-------------- 417 0,-1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAa------------- 276 0,-1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAaa------------ 31 0,-1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAau------------ 21 0,-1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAc------------- 176 0,-1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAg------------- 5 0,-1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAU------------- 4999 0,0 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUa------------ 149 0,0 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUaa----------- 42 0,0 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUau----------- 23 0,0 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUc------------ 7 0,0 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUU------------ 1062 0,1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUUa----------- 77 0,1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUUaa---------- 4 0,1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUUu----------- 71 0,1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUUG----------- 3 0,2 -------------------------------------------------------AGUGCAAUGUUAAAAGGGC--------------- 2 1,-2 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCA-------------- 14 1,-1 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAa------------- 9 1,-1 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAc------------- 7 1,-1 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAU------------- 199 1,0 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAUa------------ 7 1,0 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAUU------------ 45 1,1 --------------------------------------------------------GUGCAAUGUUAAAAGGGCAU------------- 3 2,0 >hsa-mir-130b mi:13-33;MA:51-72 Normal ggccugcccgacACUCUUUCCCUGUUGCACUACuauaggccgcugggaagCAGUGCAAUGAUGAAAGGGCAUcggucagguc ------------ACUCUUUCCCUGUUGCACU--------------------------------------------------- 2 0,-2 ------------ACUCUUUCCCUGUUGCACUA-------------------------------------------------- 2 0,-1 ------------ACUCUUUCCCUGUUGCACUAC------------------------------------------------- 2 0,0 ------------ACUCUUUCCCUGUUGCACUACU------------------------------------------------ 24 0,1 --------------------------------------------------CAGUGCAAUGAUGAAAGGGC------------ 4 0,-2 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCA----------- 20 0,-1 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAa---------- 10 0,-1 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAau--------- 2 0,-1 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAU---------- 212 0,0 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAUa--------- 4 0,0 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAUau-------- 2 0,0 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAUu--------- 23 0,0 ---------------------------------------------------AGUGCAAUGAUGAAAGGGCAa---------- 2 1,-1 ---------------------------------------------------AGUGCAAUGAUGAAAGGGCAU---------- 13 1,0 >hsa-mir-132 mi:23-44;MA:59-80 Normal ccgcccccgcgucuccagggcaACCGUGGCUUUCGAUUGUUACUgugggaacuggaggUAACAGUCUACAGCCAUGGUCGccccgcagcacgcccacgcgc ---------------------AACCGUGGCUUUCGAUUGU------------------------------------------------------------- 4 -1,-4 ---------------------AACCGUGGCUUUCGAUUGUU------------------------------------------------------------ 39 -1,-3 ---------------------AACCGUGGCUUUCGAUUGUUA----------------------------------------------------------- 18 -1,-2 ---------------------AACCGUGGCUUUCGAUUGUUAC---------------------------------------------------------- 5 -1,-1 ----------------------ACCGUGGCUUUCGAUUGUU------------------------------------------------------------ 7 0,-3 ----------------------ACCGUGGCUUUCGAUUGUUA----------------------------------------------------------- 9 0,-2 ----------------------ACCGUGGCUUUCGAUUGUUAC---------------------------------------------------------- 19 0,-1 ----------------------ACCGUGGCUUUCGAUUGUUACU--------------------------------------------------------- 62 0,0 ----------------------------------------------------------UAACAGUCUACAGCCAUGGU----------------------- 8 0,-2 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUa---------------------- 6 0,-2 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUC---------------------- 7 0,-1 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUCa--------------------- 2 0,-1 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUCu--------------------- 5 0,-1 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUCG--------------------- 235 0,0 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUCGa-------------------- 20 0,0 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUCGu-------------------- 54 0,0 -----------------------------------------------------------AACAGUCUACAGCCAUGGUCG--------------------- 27 1,0 -----------------------------------------------------------AACAGUCUACAGCCAUGGUCGu-------------------- 9 1,0 ------------------------------------------------------------ACAGUCUACAGCCAUGGUCGu-------------------- 6 2,0 >hsa-mir-133a-1 3pM:53-74 Normal acaaugcuuugcuagagcugguaaaauggaaccaaaucgccucuucaauggaUUUGGUCCCCUUCAACCAGCUGuagcuaugcauuga ----------------------------------------------------UUUGGUCCCCUUCAACCAGC---------------- 2 0,-2 ----------------------------------------------------UUUGGUCCCCUUCAACCAGCU--------------- 2 0,-1 ----------------------------------------------------UUUGGUCCCCUUCAACCAGCUGU------------- 15 0,1 -----------------------------------------------------UUGGUCCCCUUCAACCAGCUGU------------- 21 1,1 >hsa-mir-133a-2 3pM:59-80 Normal gggagccaaaugcuuugcuagagcugguaaaauggaaccaaaucgacuguccaauggaUUUGGUCCCCUUCAACCAGCUGuagcugugcauugauggcgccg ----------------------------------------------------------UUUGGUCCCCUUCAACCAGC------------------------ 2 0,-2 ----------------------------------------------------------UUUGGUCCCCUUCAACCAGCU----------------------- 2 0,-1 ----------------------------------------------------------UUUGGUCCCCUUCAACCAGCUGU--------------------- 15 0,1 -----------------------------------------------------------UUGGUCCCCUUCAACCAGCUGU--------------------- 21 1,1 >hsa-mir-133b 3pM:66-87 Normal ccucagaagaaagaugcccccugcucuggcuggucaaacggaaccaaguccgucuuccugagaggUUUGGUCCCCUUCAACCAGCUAcagcagggcuggcaaugcccaguccuuggaga -----------------------------------------------------------------UUUGGUCCCCUUCAACCAGC---------------------------------- 2 0,-2 -----------------------------------------------------------------UUUGGUCCCCUUCAACCAGCU--------------------------------- 2 0,-1 >hsa-mir-134 5pM:8-29 Normal cagggugUGUGACUGGUUGACCAGAGGGGcaugcacuguguucacccugugggccaccuagucaccaacccuc -------UGUGACUGGUUGACCAGA------------------------------------------------ 6 0,-4 -------UGUGACUGGUUGACCAGAG----------------------------------------------- 9 0,-3 -------UGUGACUGGUUGACCAGAGa---------------------------------------------- 24 0,-3 -------UGUGACUGGUUGACCAGAGu---------------------------------------------- 3 0,-3 -------UGUGACUGGUUGACCAGAGG---------------------------------------------- 102 0,-2 -------UGUGACUGGUUGACCAGAGGa--------------------------------------------- 13 0,-2 -------UGUGACUGGUUGACCAGAGGaa-------------------------------------------- 15 0,-2 -------UGUGACUGGUUGACCAGAGGG--------------------------------------------- 114 0,-1 -------UGUGACUGGUUGACCAGAGGGa-------------------------------------------- 78 0,-1 -------UGUGACUGGUUGACCAGAGGGaa------------------------------------------- 83 0,-1 -------UGUGACUGGUUGACCAGAGGGau------------------------------------------- 21 0,-1 -------UGUGACUGGUUGACCAGAGGGu-------------------------------------------- 21 0,-1 -------UGUGACUGGUUGACCAGAGGGG-------------------------------------------- 201 0,0 -------UGUGACUGGUUGACCAGAGGGGa------------------------------------------- 71 0,0 -------UGUGACUGGUUGACCAGAGGGGaa------------------------------------------ 16 0,0 -------UGUGACUGGUUGACCAGAGGGGau------------------------------------------ 36 0,0 -------UGUGACUGGUUGACCAGAGGGGu------------------------------------------- 31 0,0 -------UGUGACUGGUUGACCAGAGGGGuu------------------------------------------ 3 0,0 --------GUGACUGGUUGACCAGAGGG--------------------------------------------- 2 1,-1 --------GUGACUGGUUGACCAGAGGGa-------------------------------------------- 3 1,-1 --------GUGACUGGUUGACCAGAGGGaa------------------------------------------- 2 1,-1 --------GUGACUGGUUGACCAGAGGGG-------------------------------------------- 3 1,0 >hsa-mir-135a-1 MA:17-39;mi:56-77 Normal aggccucgcuguucucUAUGGCUUUUUAUUCCUAUGUGAuucuacugcucacucaUAUAGGGAUUGGAGCCGUGGCGcacggcggggaca ----------------UAUGGCUUUUUAUUCCUAUGUG---------------------------------------------------- 6 0,-1 ----------------UAUGGCUUUUUAUUCCUAUGUGA--------------------------------------------------- 14 0,0 >hsa-mir-135a-2 5pM:23-45 Normal agauaaauucacucuagugcuuUAUGGCUUUUUAUUCCUAUGUGAuaguaauaaagucucauguagggauggaagccaugaaauacauugugaaaaauca ----------------------UAUGGCUUUUUAUUCCUAUGUG-------------------------------------------------------- 6 0,-1 ----------------------UAUGGCUUUUUAUUCCUAUGUGA------------------------------------------------------- 14 0,0 >hsa-mir-135b MA:16-38;mi:55-76 Normal cacucugcuguggccUAUGGCUUUUCAUUCCUAUGUGAuugcugucccaaacucAUGUAGGGCUAAAAGCCAUGGGcuacagugaggggcgagcucc ---------------UAUGGCUUUUCAUUCCUAUGU------------------------------------------------------------- 10 0,-2 ---------------UAUGGCUUUUCAUUCCUAUGUG------------------------------------------------------------ 29 0,-1 ---------------UAUGGCUUUUCAUUCCUAUGUGu----------------------------------------------------------- 6 0,-1 ---------------UAUGGCUUUUCAUUCCUAUGUGA----------------------------------------------------------- 40 0,0 >hsa-mir-136 MA:15-37;mi:49-70 Normal ugagcccucggaggACUCCAUUUGUUUUGAUGAUGGAuucuuaugcucCAUCAUCGUCUCAAAUGAGUCUucagaggguucu ------------GGACUCCAUUUGUUUUGAUGA------------------------------------------------- 2 -2,-4 --------------ACUCCAUUUGUUUUGAUG-------------------------------------------------- 2 0,-5 --------------ACUCCAUUUGUUUUGAUGAU------------------------------------------------ 47 0,-3 --------------ACUCCAUUUGUUUUGAUGAUu----------------------------------------------- 2 0,-3 --------------ACUCCAUUUGUUUUGAUGAUG----------------------------------------------- 255 0,-2 --------------ACUCCAUUUGUUUUGAUGAUGa---------------------------------------------- 20 0,-2 --------------ACUCCAUUUGUUUUGAUGAUGaa--------------------------------------------- 4 0,-2 --------------ACUCCAUUUGUUUUGAUGAUGu---------------------------------------------- 7 0,-2 --------------ACUCCAUUUGUUUUGAUGAUGG---------------------------------------------- 766 0,-1 --------------ACUCCAUUUGUUUUGAUGAUGGu--------------------------------------------- 2 0,-1 --------------ACUCCAUUUGUUUUGAUGAUGGA--------------------------------------------- 759 0,0 --------------ACUCCAUUUGUUUUGAUGAUGGAa-------------------------------------------- 43 0,0 --------------ACUCCAUUUGUUUUGAUGAUGGAU-------------------------------------------- 3 0,1 ---------------CUCCAUUUGUUUUGAUGAUGGA--------------------------------------------- 5 1,0 ------------------------------------------------CAUCAUCGUCUCAAAUGAGU-------------- 8 0,-2 ------------------------------------------------CAUCAUCGUCUCAAAUGAGUC------------- 10 0,-1 ------------------------------------------------CAUCAUCGUCUCAAAUGAGUCU------------ 60 0,0 -------------------------------------------------AUCAUCGUCUCAAAUGAGU-------------- 5 1,-2 -------------------------------------------------AUCAUCGUCUCAAAUGAGUC------------- 3 1,-1 -------------------------------------------------AUCAUCGUCUCAAAUGAGUCU------------ 118 1,0 -------------------------------------------------AUCAUCGUCUCAAAUGAGUCUU----------- 10 1,1 -------------------------------------------------AUCAUCGUCUCAAAUGAGUCUUu---------- 2 1,1 --------------------------------------------------UCAUCGUCUCAAAUGAGUCU------------ 2 2,0 --------------------------------------------------UCAUCGUCUCAAAUGAGUCUU----------- 3 2,1 --------------------------------------------------UCAUCGUCUCAAAUGAGUCUUCu--------- 4 2,2 >hsa-mir-138-1 MA:23-45;mi:63-84 Normal cccuggcauggugugguggggcAGCUGGUGUUGUGAAUCAGGCCGuugccaaucagagaacgGCUACUUCACAACACCAGGGCCacaccacacuacagg ----------------------AGCUGGUGUUGUGAAUCAGG--------------------------------------------------------- 18 0,-3 ----------------------AGCUGGUGUUGUGAAUCAGGa-------------------------------------------------------- 2 0,-3 ----------------------AGCUGGUGUUGUGAAUCAGGC-------------------------------------------------------- 23 0,-2 ----------------------AGCUGGUGUUGUGAAUCAGGCa------------------------------------------------------- 5 0,-2 ----------------------AGCUGGUGUUGUGAAUCAGGCC------------------------------------------------------- 2 0,-1 ----------------------AGCUGGUGUUGUGAAUCAGGCCa------------------------------------------------------ 2 0,-1 ----------------------AGCUGGUGUUGUGAAUCAGGCCG------------------------------------------------------ 56 0,0 ----------------------AGCUGGUGUUGUGAAUCAGGCCGU----------------------------------------------------- 56 0,1 ----------------------AGCUGGUGUUGUGAAUCAGGCCGUa---------------------------------------------------- 2 0,1 ----------------------AGCUGGUGUUGUGAAUCAGGCCGUU---------------------------------------------------- 23 0,2 >hsa-mir-138-2 MA:10-32;mi:57-78 Normal cguugcugcAGCUGGUGUUGUGAAUCAGGCCGacgagcagcgcauccucuuacccgGCUAUUUCACGACACCAGGGUUgcauca ---------AGCUGGUGUUGUGAAUCAGG------------------------------------------------------- 18 0,-3 ---------AGCUGGUGUUGUGAAUCAGGa------------------------------------------------------ 2 0,-3 ---------AGCUGGUGUUGUGAAUCAGGC------------------------------------------------------ 23 0,-2 ---------AGCUGGUGUUGUGAAUCAGGCa----------------------------------------------------- 5 0,-2 ---------AGCUGGUGUUGUGAAUCAGGCC----------------------------------------------------- 2 0,-1 ---------AGCUGGUGUUGUGAAUCAGGCCa---------------------------------------------------- 2 0,-1 ---------AGCUGGUGUUGUGAAUCAGGCCG---------------------------------------------------- 56 0,0 ---------AGCUGGUGUUGUGAAUCAGGCCGA--------------------------------------------------- 19 0,1 >hsa-mir-139 5p:7-28;3p:44-65 Normal guguauUCUACAGUGCACGUGUCUCCAGuguggcucggaggcuGGAGACGCGGCCCUGUUGGAGUaac ------UCUACAGUGCACGUGUCU-------------------------------------------- 10 0,-4 ------UCUACAGUGCACGUGUCUCC------------------------------------------ 13 0,-2 ------UCUACAGUGCACGUGUCUCCA----------------------------------------- 75 0,-1 ------UCUACAGUGCACGUGUCUCCAu---------------------------------------- 6 0,-1 ------UCUACAGUGCACGUGUCUCCAG---------------------------------------- 103 0,0 ------UCUACAGUGCACGUGUCUCCAGa--------------------------------------- 28 0,0 ------UCUACAGUGCACGUGUCUCCAGU--------------------------------------- 297 0,1 ------UCUACAGUGCACGUGUCUCCAGUu-------------------------------------- 2 0,1 -------CUACAGUGCACGUGUCUCCAG---------------------------------------- 7 1,0 -------CUACAGUGCACGUGUCUCCAGU--------------------------------------- 7 1,1 ------------------------------------------UGGAGACGCGGCCCUGUUG------- 2 -1,-4 ------------------------------------------UGGAGACGCGGCCCUGUUGGA----- 31 -1,-2 ------------------------------------------UGGAGACGCGGCCCUGUUGGAa---- 30 -1,-2 ------------------------------------------UGGAGACGCGGCCCUGUUGGAaa--- 14 -1,-2 ------------------------------------------UGGAGACGCGGCCCUGUUGGAu---- 4 -1,-2 ------------------------------------------UGGAGACGCGGCCCUGUUGGAG---- 38 -1,-1 ------------------------------------------UGGAGACGCGGCCCUGUUGGAGa--- 33 -1,-1 ------------------------------------------UGGAGACGCGGCCCUGUUGGAGU--- 97 -1,0 -------------------------------------------GGAGACGCGGCCCUGUUGGAGU--- 7 0,0 >hsa-mir-140 5p:23-44;3p:62-82 Normal ugugucucucucuguguccugcCAGUGGUUUUACCCUAUGGUAGguuacgucaugcuguucUACCACAGGGUAGAACCACGGacaggauaccggggcacc ----------------------CAGUGGUUUUACCCUAUG------------------------------------------------------------ 4 0,-4 ----------------------CAGUGGUUUUACCCUAUGG----------------------------------------------------------- 16 0,-3 ----------------------CAGUGGUUUUACCCUAUGGa---------------------------------------------------------- 4 0,-3 ----------------------CAGUGGUUUUACCCUAUGGU---------------------------------------------------------- 123 0,-2 ----------------------CAGUGGUUUUACCCUAUGGUu--------------------------------------------------------- 2 0,-2 ----------------------CAGUGGUUUUACCCUAUGGUA--------------------------------------------------------- 74 0,-1 ----------------------CAGUGGUUUUACCCUAUGGUAa-------------------------------------------------------- 88 0,-1 ----------------------CAGUGGUUUUACCCUAUGGUAaa------------------------------------------------------- 7 0,-1 ----------------------CAGUGGUUUUACCCUAUGGUAu-------------------------------------------------------- 12 0,-1 ----------------------CAGUGGUUUUACCCUAUGGUAG-------------------------------------------------------- 331 0,0 ----------------------CAGUGGUUUUACCCUAUGGUAGa------------------------------------------------------- 68 0,0 ----------------------CAGUGGUUUUACCCUAUGGUAGu------------------------------------------------------- 26 0,0 ----------------------CAGUGGUUUUACCCUAUGGUAGG------------------------------------------------------- 4 0,1 -----------------------AGUGGUUUUACCCUAUGGU---------------------------------------------------------- 2 1,-2 -----------------------AGUGGUUUUACCCUAUGGUA--------------------------------------------------------- 2 1,-1 -----------------------AGUGGUUUUACCCUAUGGUAa-------------------------------------------------------- 3 1,-1 -----------------------AGUGGUUUUACCCUAUGGUAG-------------------------------------------------------- 3 1,0 -----------------------AGUGGUUUUACCCUAUGGUAGGU------------------------------------------------------ 2 1,2 -------------------------------------------------------------UACCACAGGGUAGAACCA--------------------- 2 0,-3 -------------------------------------------------------------UACCACAGGGUAGAACCAC-------------------- 7 0,-2 -------------------------------------------------------------UACCACAGGGUAGAACCACG------------------- 32 0,-1 -------------------------------------------------------------UACCACAGGGUAGAACCACGa------------------ 6 0,-1 -------------------------------------------------------------UACCACAGGGUAGAACCACGG------------------ 204 0,0 -------------------------------------------------------------UACCACAGGGUAGAACCACGGc----------------- 2 0,0 -------------------------------------------------------------UACCACAGGGUAGAACCACGGu----------------- 15 0,0 -------------------------------------------------------------UACCACAGGGUAGAACCACGGA----------------- 763 0,1 -------------------------------------------------------------UACCACAGGGUAGAACCACGGAa---------------- 367 0,1 -------------------------------------------------------------UACCACAGGGUAGAACCACGGAaa--------------- 77 0,1 -------------------------------------------------------------UACCACAGGGUAGAACCACGGAau--------------- 16 0,1 -------------------------------------------------------------UACCACAGGGUAGAACCACGGAg---------------- 11 0,1 -------------------------------------------------------------UACCACAGGGUAGAACCACGGAu---------------- 75 0,1 -------------------------------------------------------------UACCACAGGGUAGAACCACGGAC---------------- 244 0,2 -------------------------------------------------------------UACCACAGGGUAGAACCACGGACg--------------- 3 0,2 -------------------------------------------------------------UACCACAGGGUAGAACCACGGACu--------------- 33 0,2 -------------------------------------------------------------UACCACAGGGUAGAACCACGGACA--------------- 78 0,3 --------------------------------------------------------------ACCACAGGGUAGAACCAC-------------------- 19 1,-2 --------------------------------------------------------------ACCACAGGGUAGAACCACG------------------- 21 1,-1 --------------------------------------------------------------ACCACAGGGUAGAACCACGa------------------ 2 1,-1 --------------------------------------------------------------ACCACAGGGUAGAACCACGG------------------ 177 1,0 --------------------------------------------------------------ACCACAGGGUAGAACCACGGu----------------- 9 1,0 --------------------------------------------------------------ACCACAGGGUAGAACCACGGA----------------- 1543 1,1 --------------------------------------------------------------ACCACAGGGUAGAACCACGGAa---------------- 825 1,1 --------------------------------------------------------------ACCACAGGGUAGAACCACGGAaa--------------- 527 1,1 --------------------------------------------------------------ACCACAGGGUAGAACCACGGAau--------------- 109 1,1 --------------------------------------------------------------ACCACAGGGUAGAACCACGGAg---------------- 12 1,1 --------------------------------------------------------------ACCACAGGGUAGAACCACGGAu---------------- 210 1,1 --------------------------------------------------------------ACCACAGGGUAGAACCACGGAuu--------------- 9 1,1 --------------------------------------------------------------ACCACAGGGUAGAACCACGGAC---------------- 1791 1,2 --------------------------------------------------------------ACCACAGGGUAGAACCACGGACg--------------- 38 1,2 --------------------------------------------------------------ACCACAGGGUAGAACCACGGACu--------------- 283 1,2 --------------------------------------------------------------ACCACAGGGUAGAACCACGGACA--------------- 847 1,3 --------------------------------------------------------------ACCACAGGGUAGAACCACGGACAa-------------- 21 1,3 --------------------------------------------------------------ACCACAGGGUAGAACCACGGACAu-------------- 6 1,3 --------------------------------------------------------------ACCACAGGGUAGAACCACGGACAG-------------- 2 1,4 ---------------------------------------------------------------CCACAGGGUAGAACCACGG------------------ 2 2,0 ---------------------------------------------------------------CCACAGGGUAGAACCACGGA----------------- 31 2,1 ---------------------------------------------------------------CCACAGGGUAGAACCACGGAa---------------- 21 2,1 ---------------------------------------------------------------CCACAGGGUAGAACCACGGAaa--------------- 18 2,1 ---------------------------------------------------------------CCACAGGGUAGAACCACGGAu---------------- 2 2,1 ---------------------------------------------------------------CCACAGGGUAGAACCACGGAC---------------- 51 2,2 ---------------------------------------------------------------CCACAGGGUAGAACCACGGACu--------------- 13 2,2 ---------------------------------------------------------------CCACAGGGUAGAACCACGGACA--------------- 30 2,3 ---------------------------------------------------------------CCACAGGGUAGAACCACGGACAa-------------- 2 2,3 >hsa-mir-141 mi:17-38;MA:59-80 Normal cggccggcccugggucCAUCUUCCAGUACAGUGUUGGAuggucuaauugugaagcuccUAACACUGUCUGGUAAAGAUGGcucccggguggguuc ----------------CAUCUUCCAGUACAGUGUUGG---------------------------------------------------------- 2 0,-1 ----------------CAUCUUCCAGUACAGUGUUGGA--------------------------------------------------------- 37 0,0 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAU----------------- 4 -1,-2 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAUG---------------- 20 -1,-1 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAUGa--------------- 2 -1,-1 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAUGG--------------- 13 -1,0 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAUGGa-------------- 2 -1,0 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAUGGC-------------- 2 -1,1 ----------------------------------------------------------UAACACUGUCUGGUAAAG------------------- 60 0,-4 ----------------------------------------------------------UAACACUGUCUGGUAAAGu------------------ 5 0,-4 ----------------------------------------------------------UAACACUGUCUGGUAAAGuu----------------- 4 0,-4 ----------------------------------------------------------UAACACUGUCUGGUAAAGA------------------ 186 0,-3 ----------------------------------------------------------UAACACUGUCUGGUAAAGAa----------------- 78 0,-3 ----------------------------------------------------------UAACACUGUCUGGUAAAGAaa---------------- 129 0,-3 ----------------------------------------------------------UAACACUGUCUGGUAAAGAau---------------- 2 0,-3 ----------------------------------------------------------UAACACUGUCUGGUAAAGAU----------------- 543 0,-2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUa---------------- 235 0,-2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUaa--------------- 36 0,-2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUc---------------- 2 0,-2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUu---------------- 28 0,-2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUuu--------------- 3 0,-2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUG---------------- 2254 0,-1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGa--------------- 438 0,-1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGaa-------------- 13 0,-1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGau-------------- 3 0,-1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGu--------------- 145 0,-1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGG--------------- 5259 0,0 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGa-------------- 665 0,0 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGaa------------- 2 0,0 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGg-------------- 2 0,0 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGu-------------- 363 0,0 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGC-------------- 2627 0,1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGCa------------- 74 0,1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGCau------------ 6 0,1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGCg------------- 4 0,1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGCU------------- 202 0,2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGCUu------------ 6 0,2 -----------------------------------------------------------AACACUGUCUGGUAAAGAa----------------- 2 1,-3 -----------------------------------------------------------AACACUGUCUGGUAAAGAaa---------------- 2 1,-3 -----------------------------------------------------------AACACUGUCUGGUAAAGAU----------------- 18 1,-2 -----------------------------------------------------------AACACUGUCUGGUAAAGAUa---------------- 5 1,-2 -----------------------------------------------------------AACACUGUCUGGUAAAGAUG---------------- 104 1,-1 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGa--------------- 13 1,-1 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGG--------------- 213 1,0 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGGa-------------- 25 1,0 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGGu-------------- 9 1,0 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGGC-------------- 114 1,1 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGGCU------------- 15 1,2 ------------------------------------------------------------ACACUGUCUGGUAAAGAUG---------------- 7 2,-1 ------------------------------------------------------------ACACUGUCUGGUAAAGAUGG--------------- 4 2,0 ------------------------------------------------------------ACACUGUCUGGUAAAGAUGGC-------------- 3 2,1 >hsa-mir-142 5p:16-36;3p:52-74 Normal gacagugcagucaccCAUAAAGUAGAAAGCACUACUaacagcacuggagggUGUAGUGUUUCCUACUUUAUGGAugaguguacugug -------------CCCAUAAAGUAGAAAGCA-------------------------------------------------------- 16 -2,-5 -------------CCCAUAAAGUAGAAAGCAa------------------------------------------------------- 4 -2,-5 -------------CCCAUAAAGUAGAAAGCAuu------------------------------------------------------ 2 -2,-5 -------------CCCAUAAAGUAGAAAGCAC------------------------------------------------------- 18 -2,-4 -------------CCCAUAAAGUAGAAAGCACU------------------------------------------------------ 511 -2,-3 -------------CCCAUAAAGUAGAAAGCACUA----------------------------------------------------- 205 -2,-2 -------------CCCAUAAAGUAGAAAGCACUAa---------------------------------------------------- 14 -2,-2 -------------CCCAUAAAGUAGAAAGCACUAu---------------------------------------------------- 14 -2,-2 -------------CCCAUAAAGUAGAAAGCACUAC---------------------------------------------------- 165 -2,-1 -------------CCCAUAAAGUAGAAAGCACUACa--------------------------------------------------- 25 -2,-1 -------------CCCAUAAAGUAGAAAGCACUACU--------------------------------------------------- 3 -2,0 --------------CCAUAAAGUAGAAAGCACU------------------------------------------------------ 21 -1,-3 --------------CCAUAAAGUAGAAAGCACUA----------------------------------------------------- 6 -1,-2 ---------------CAUAAAGUAGAAAGCACU------------------------------------------------------ 40 0,-3 ---------------CAUAAAGUAGAAAGCACUA----------------------------------------------------- 86 0,-2 ---------------CAUAAAGUAGAAAGCACUAa---------------------------------------------------- 5 0,-2 ---------------CAUAAAGUAGAAAGCACUAaa--------------------------------------------------- 2 0,-2 ---------------CAUAAAGUAGAAAGCACUAC---------------------------------------------------- 76 0,-1 ---------------CAUAAAGUAGAAAGCACUACa--------------------------------------------------- 14 0,-1 ---------------CAUAAAGUAGAAAGCACUACU--------------------------------------------------- 864 0,0 ---------------CAUAAAGUAGAAAGCACUACUu-------------------------------------------------- 2 0,0 ---------------CAUAAAGUAGAAAGCACUACUA-------------------------------------------------- 101 0,1 ---------------CAUAAAGUAGAAAGCACUACUAu------------------------------------------------- 9 0,1 ---------------CAUAAAGUAGAAAGCACUACUAA------------------------------------------------- 20 0,2 ----------------AUAAAGUAGAAAGCACUA----------------------------------------------------- 5 1,-2 ----------------AUAAAGUAGAAAGCACUAC---------------------------------------------------- 9 1,-1 ----------------AUAAAGUAGAAAGCACUACU--------------------------------------------------- 215 1,0 ----------------AUAAAGUAGAAAGCACUACUA-------------------------------------------------- 26 1,1 ----------------AUAAAGUAGAAAGCACUACUAu------------------------------------------------- 10 1,1 ----------------AUAAAGUAGAAAGCACUACUAA------------------------------------------------- 61 1,2 ---------------------------------------------------UGUAGUGUUUCCUACUUU------------------ 5 0,-5 ---------------------------------------------------UGUAGUGUUUCCUACUUUAU---------------- 79 0,-3 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUu--------------- 13 0,-3 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUuu-------------- 6 0,-3 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUG--------------- 44 0,-2 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGa-------------- 28 0,-2 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGaa------------- 2 0,-2 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGu-------------- 28 0,-2 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGG-------------- 681 0,-1 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGGu------------- 27 0,-1 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGGA------------- 402 0,0 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGGAa------------ 7 0,0 ----------------------------------------------------GUAGUGUUUCCUACUUUAU---------------- 69 1,-3 ----------------------------------------------------GUAGUGUUUCCUACUUUAUu--------------- 3 1,-3 ----------------------------------------------------GUAGUGUUUCCUACUUUAUuu-------------- 5 1,-3 ----------------------------------------------------GUAGUGUUUCCUACUUUAUG--------------- 46 1,-2 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGa-------------- 5 1,-2 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGu-------------- 57 1,-2 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGG-------------- 636 1,-1 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGc------------- 2 1,-1 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGu------------- 29 1,-1 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGA------------- 794 1,0 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGAa------------ 71 1,0 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGAU------------ 6 1,1 -----------------------------------------------------UAGUGUUUCCUACUUUAUG--------------- 2 2,-2 -----------------------------------------------------UAGUGUUUCCUACUUUAUGG-------------- 2 2,-1 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGu------------- 2 2,-1 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGA------------- 15 2,0 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGAa------------ 3 2,0 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGAU------------ 2 2,1 >hsa-mir-143 mi:27-48;MA:61-81 Normal gcgcagcgcccugucucccagccugaGGUGCAGUGCUGCAUCUCUGGUcaguugggagucUGAGAUGAAGCACUGUAGCUCaggaagagagaaguuguucugcagc -------------------------AGGUGCAGUGCUGCAUCUCU------------------------------------------------------------- 20 -1,-3 -------------------------AGGUGCAGUGCUGCAUCUCUG------------------------------------------------------------ 29 -1,-2 -------------------------AGGUGCAGUGCUGCAUCUCUGa----------------------------------------------------------- 84 -1,-2 -------------------------AGGUGCAGUGCUGCAUCUCUGaa---------------------------------------------------------- 9 -1,-2 -------------------------AGGUGCAGUGCUGCAUCUCUGu----------------------------------------------------------- 18 -1,-2 -------------------------AGGUGCAGUGCUGCAUCUCUGG----------------------------------------------------------- 346 -1,-1 -------------------------AGGUGCAGUGCUGCAUCUCUGGa---------------------------------------------------------- 523 -1,-1 -------------------------AGGUGCAGUGCUGCAUCUCUGGaa--------------------------------------------------------- 55 -1,-1 -------------------------AGGUGCAGUGCUGCAUCUCUGGau--------------------------------------------------------- 20 -1,-1 -------------------------AGGUGCAGUGCUGCAUCUCUGGc---------------------------------------------------------- 2 -1,-1 -------------------------AGGUGCAGUGCUGCAUCUCUGGU---------------------------------------------------------- 79 -1,0 -------------------------AGGUGCAGUGCUGCAUCUCUGGUu--------------------------------------------------------- 5 -1,0 -------------------------AGGUGCAGUGCUGCAUCUCUGGUuu-------------------------------------------------------- 2 -1,0 --------------------------GGUGCAGUGCUGCAUCUC-------------------------------------------------------------- 30 0,-4 --------------------------GGUGCAGUGCUGCAUCUCU------------------------------------------------------------- 48 0,-3 --------------------------GGUGCAGUGCUGCAUCUCUG------------------------------------------------------------ 114 0,-2 --------------------------GGUGCAGUGCUGCAUCUCUGa----------------------------------------------------------- 317 0,-2 --------------------------GGUGCAGUGCUGCAUCUCUGaa---------------------------------------------------------- 41 0,-2 --------------------------GGUGCAGUGCUGCAUCUCUGau---------------------------------------------------------- 8 0,-2 --------------------------GGUGCAGUGCUGCAUCUCUGc----------------------------------------------------------- 8 0,-2 --------------------------GGUGCAGUGCUGCAUCUCUGu----------------------------------------------------------- 67 0,-2 --------------------------GGUGCAGUGCUGCAUCUCUGuu---------------------------------------------------------- 3 0,-2 --------------------------GGUGCAGUGCUGCAUCUCUGG----------------------------------------------------------- 5362 0,-1 --------------------------GGUGCAGUGCUGCAUCUCUGGa---------------------------------------------------------- 2065 0,-1 --------------------------GGUGCAGUGCUGCAUCUCUGGaa--------------------------------------------------------- 1018 0,-1 --------------------------GGUGCAGUGCUGCAUCUCUGGau--------------------------------------------------------- 236 0,-1 --------------------------GGUGCAGUGCUGCAUCUCUGGc---------------------------------------------------------- 6 0,-1 --------------------------GGUGCAGUGCUGCAUCUCUGGg---------------------------------------------------------- 5 0,-1 --------------------------GGUGCAGUGCUGCAUCUCUGGU---------------------------------------------------------- 1798 0,0 --------------------------GGUGCAGUGCUGCAUCUCUGGUa--------------------------------------------------------- 192 0,0 --------------------------GGUGCAGUGCUGCAUCUCUGGUaa-------------------------------------------------------- 31 0,0 --------------------------GGUGCAGUGCUGCAUCUCUGGUau-------------------------------------------------------- 53 0,0 --------------------------GGUGCAGUGCUGCAUCUCUGGUg--------------------------------------------------------- 10 0,0 --------------------------GGUGCAGUGCUGCAUCUCUGGUu--------------------------------------------------------- 160 0,0 --------------------------GGUGCAGUGCUGCAUCUCUGGUuu-------------------------------------------------------- 19 0,0 --------------------------GGUGCAGUGCUGCAUCUCUGGUC--------------------------------------------------------- 133 0,1 --------------------------GGUGCAGUGCUGCAUCUCUGGUCu-------------------------------------------------------- 38 0,1 --------------------------GGUGCAGUGCUGCAUCUCUGGUCuu------------------------------------------------------- 2 0,1 --------------------------GGUGCAGUGCUGCAUCUCUGGUCA-------------------------------------------------------- 31 0,2 --------------------------GGUGCAGUGCUGCAUCUCUGGUCAu------------------------------------------------------- 3 0,2 ----------------------------------------------------------UCUGAGAUGAAGCACUGUAGCUC------------------------- 5 -2,0 ----------------------------------------------------------UCUGAGAUGAAGCACUGUAGCUCu------------------------ 8 -2,0 -----------------------------------------------------------CUGAGAUGAAGCACUGUAG---------------------------- 22 -1,-3 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGa--------------------------- 4 -1,-3 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGC--------------------------- 13 -1,-2 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCaa------------------------- 2 -1,-2 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCU-------------------------- 92 -1,-1 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUa------------------------- 4 -1,-1 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUaa------------------------ 9 -1,-1 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUu------------------------- 3 -1,-1 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUuu------------------------ 2 -1,-1 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUC------------------------- 139 -1,0 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUCu------------------------ 196 -1,0 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUCuu----------------------- 17 -1,0 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUCA------------------------ 51 -1,1 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUCAu----------------------- 2 -1,1 ------------------------------------------------------------UGAGAUGAAGCACUGUAG---------------------------- 2312 0,-3 ------------------------------------------------------------UGAGAUGAAGCACUGUAGa--------------------------- 601 0,-3 ------------------------------------------------------------UGAGAUGAAGCACUGUAGaa-------------------------- 296 0,-3 ------------------------------------------------------------UGAGAUGAAGCACUGUAGau-------------------------- 35 0,-3 ------------------------------------------------------------UGAGAUGAAGCACUGUAGu--------------------------- 48 0,-3 ------------------------------------------------------------UGAGAUGAAGCACUGUAGuu-------------------------- 25 0,-3 ------------------------------------------------------------UGAGAUGAAGCACUGUAGC--------------------------- 1574 0,-2 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCa-------------------------- 368 0,-2 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCaa------------------------- 453 0,-2 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCau------------------------- 12 0,-2 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCc-------------------------- 17 0,-2 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCg-------------------------- 13 0,-2 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCU-------------------------- 10115 0,-1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUa------------------------- 1024 0,-1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUaa------------------------ 310 0,-1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUau------------------------ 177 0,-1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUg------------------------- 41 0,-1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUu------------------------- 608 0,-1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUuu------------------------ 407 0,-1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUC------------------------- 25276 0,0 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCc------------------------ 194 0,0 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCg------------------------ 131 0,0 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCu------------------------ 43934 0,0 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCuu----------------------- 4813 0,0 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCA------------------------ 8822 0,1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAa----------------------- 596 0,1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAaa---------------------- 13 0,1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAau---------------------- 3 0,1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAu----------------------- 544 0,1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAuu---------------------- 5 0,1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAG----------------------- 80 0,2 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAGa---------------------- 5 0,2 -------------------------------------------------------------GAGAUGAAGCACUGUAGC--------------------------- 49 1,-2 -------------------------------------------------------------GAGAUGAAGCACUGUAGCa-------------------------- 13 1,-2 -------------------------------------------------------------GAGAUGAAGCACUGUAGCaa------------------------- 6 1,-2 -------------------------------------------------------------GAGAUGAAGCACUGUAGCg-------------------------- 2 1,-2 -------------------------------------------------------------GAGAUGAAGCACUGUAGCU-------------------------- 266 1,-1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUa------------------------- 39 1,-1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUaa------------------------ 6 1,-1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUau------------------------ 2 1,-1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUu------------------------- 9 1,-1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUuu------------------------ 12 1,-1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUC------------------------- 913 1,0 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUCc------------------------ 5 1,0 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUCg------------------------ 4 1,0 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUCu------------------------ 1626 1,0 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUCuu----------------------- 184 1,0 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUCA------------------------ 305 1,1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUCAa----------------------- 10 1,1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUCAu----------------------- 15 1,1 --------------------------------------------------------------AGAUGAAGCACUGUAGCU-------------------------- 19 2,-1 --------------------------------------------------------------AGAUGAAGCACUGUAGCUa------------------------- 2 2,-1 --------------------------------------------------------------AGAUGAAGCACUGUAGCUC------------------------- 35 2,0 --------------------------------------------------------------AGAUGAAGCACUGUAGCUCu------------------------ 74 2,0 --------------------------------------------------------------AGAUGAAGCACUGUAGCUCuu----------------------- 4 2,0 --------------------------------------------------------------AGAUGAAGCACUGUAGCUCA------------------------ 11 2,1 >hsa-mir-144 mi:15-36;MA:52-71 Normal uggggcccuggcugGGAUAUCAUCAUAUACUGUAAGuuugcgaugagacacUACAGUAUAGAUGAUGUACUaguccgggcaccccc --------------GGAUAUCAUCAUAUACUG------------------------------------------------------ 6 0,-4 --------------GGAUAUCAUCAUAUACUGU----------------------------------------------------- 18 0,-3 --------------GGAUAUCAUCAUAUACUGUA---------------------------------------------------- 19 0,-2 --------------GGAUAUCAUCAUAUACUGUAA--------------------------------------------------- 101 0,-1 --------------GGAUAUCAUCAUAUACUGUAAu-------------------------------------------------- 2 0,-1 --------------GGAUAUCAUCAUAUACUGUAAuu------------------------------------------------- 7 0,-1 --------------GGAUAUCAUCAUAUACUGUAAG-------------------------------------------------- 388 0,0 --------------GGAUAUCAUCAUAUACUGUAAGa------------------------------------------------- 4 0,0 --------------GGAUAUCAUCAUAUACUGUAAGc------------------------------------------------- 3 0,0 --------------GGAUAUCAUCAUAUACUGUAAGU------------------------------------------------- 361 0,1 --------------GGAUAUCAUCAUAUACUGUAAGUU------------------------------------------------ 23 0,2 ---------------GAUAUCAUCAUAUACUGUAAG-------------------------------------------------- 14 1,0 ---------------GAUAUCAUCAUAUACUGUAAGU------------------------------------------------- 32 1,1 ---------------GAUAUCAUCAUAUACUGUAAGUa------------------------------------------------ 2 1,1 ---------------GAUAUCAUCAUAUACUGUAAGUU------------------------------------------------ 44 1,2 --------------------------------------------------CUACAGUAUAGAUGAUGU------------------ 13 -1,-3 --------------------------------------------------CUACAGUAUAGAUGAUGUc----------------- 2 -1,-3 --------------------------------------------------CUACAGUAUAGAUGAUGUA----------------- 241 -1,-2 --------------------------------------------------CUACAGUAUAGAUGAUGUAa---------------- 5 -1,-2 --------------------------------------------------CUACAGUAUAGAUGAUGUAau--------------- 3 -1,-2 --------------------------------------------------CUACAGUAUAGAUGAUGUAu---------------- 3 -1,-2 --------------------------------------------------CUACAGUAUAGAUGAUGUAC---------------- 359 -1,-1 --------------------------------------------------CUACAGUAUAGAUGAUGUACU--------------- 980 -1,0 --------------------------------------------------CUACAGUAUAGAUGAUGUACUuu------------- 3 -1,0 --------------------------------------------------CUACAGUAUAGAUGAUGUACUA-------------- 4 -1,1 --------------------------------------------------CUACAGUAUAGAUGAUGUACUAu------------- 3 -1,1 ---------------------------------------------------UACAGUAUAGAUGAUGUA----------------- 736 0,-2 ---------------------------------------------------UACAGUAUAGAUGAUGUAa---------------- 50 0,-2 ---------------------------------------------------UACAGUAUAGAUGAUGUAaa--------------- 3 0,-2 ---------------------------------------------------UACAGUAUAGAUGAUGUAau--------------- 10 0,-2 ---------------------------------------------------UACAGUAUAGAUGAUGUAg---------------- 5 0,-2 ---------------------------------------------------UACAGUAUAGAUGAUGUAu---------------- 12 0,-2 ---------------------------------------------------UACAGUAUAGAUGAUGUAuu--------------- 9 0,-2 ---------------------------------------------------UACAGUAUAGAUGAUGUAC---------------- 1682 0,-1 ---------------------------------------------------UACAGUAUAGAUGAUGUACa--------------- 8 0,-1 ---------------------------------------------------UACAGUAUAGAUGAUGUACc--------------- 10 0,-1 ---------------------------------------------------UACAGUAUAGAUGAUGUACU--------------- 5358 0,0 ---------------------------------------------------UACAGUAUAGAUGAUGUACUu-------------- 15 0,0 ---------------------------------------------------UACAGUAUAGAUGAUGUACUuu------------- 7 0,0 ---------------------------------------------------UACAGUAUAGAUGAUGUACUA-------------- 49 0,1 ---------------------------------------------------UACAGUAUAGAUGAUGUACUAa------------- 5 0,1 ---------------------------------------------------UACAGUAUAGAUGAUGUACUAaa------------ 4 0,1 ---------------------------------------------------UACAGUAUAGAUGAUGUACUAu------------- 4 0,1 ---------------------------------------------------UACAGUAUAGAUGAUGUACUAG------------- 9 0,2 ----------------------------------------------------ACAGUAUAGAUGAUGUAC---------------- 67 1,-1 ----------------------------------------------------ACAGUAUAGAUGAUGUACU--------------- 219 1,0 ----------------------------------------------------ACAGUAUAGAUGAUGUACUAu------------- 2 1,1 -----------------------------------------------------CAGUAUAGAUGAUGUACU--------------- 5 2,0 >hsa-mir-145 MA:16-38;mi:54-75 Normal caccuuguccucacgGUCCAGUUUUCCCAGGAAUCCCUuagaugcuaagauggGGAUUCCUGGAAAUACUGUUCUugaggucaugguu --------------GGUCCAGUUUUCCCAGGAAU------------------------------------------------------ 2 -1,-4 --------------GGUCCAGUUUUCCCAGGAAUCC---------------------------------------------------- 3 -1,-2 --------------GGUCCAGUUUUCCCAGGAAUCCC--------------------------------------------------- 3 -1,-1 --------------GGUCCAGUUUUCCCAGGAAUCCCU-------------------------------------------------- 7 -1,0 ---------------GUCCAGUUUUCCCAGGAA------------------------------------------------------- 566 0,-5 ---------------GUCCAGUUUUCCCAGGAAa------------------------------------------------------ 736 0,-5 ---------------GUCCAGUUUUCCCAGGAAaa----------------------------------------------------- 230 0,-5 ---------------GUCCAGUUUUCCCAGGAAau----------------------------------------------------- 10 0,-5 ---------------GUCCAGUUUUCCCAGGAAc------------------------------------------------------ 13 0,-5 ---------------GUCCAGUUUUCCCAGGAAg------------------------------------------------------ 46 0,-5 ---------------GUCCAGUUUUCCCAGGAAU------------------------------------------------------ 4011 0,-4 ---------------GUCCAGUUUUCCCAGGAAUa----------------------------------------------------- 35 0,-4 ---------------GUCCAGUUUUCCCAGGAAUaa---------------------------------------------------- 18 0,-4 ---------------GUCCAGUUUUCCCAGGAAUu----------------------------------------------------- 29 0,-4 ---------------GUCCAGUUUUCCCAGGAAUC----------------------------------------------------- 1957 0,-3 ---------------GUCCAGUUUUCCCAGGAAUCa---------------------------------------------------- 380 0,-3 ---------------GUCCAGUUUUCCCAGGAAUCaa--------------------------------------------------- 39 0,-3 ---------------GUCCAGUUUUCCCAGGAAUCau--------------------------------------------------- 3 0,-3 ---------------GUCCAGUUUUCCCAGGAAUCg---------------------------------------------------- 38 0,-3 ---------------GUCCAGUUUUCCCAGGAAUCu---------------------------------------------------- 73 0,-3 ---------------GUCCAGUUUUCCCAGGAAUCC---------------------------------------------------- 9946 0,-2 ---------------GUCCAGUUUUCCCAGGAAUCCa--------------------------------------------------- 1112 0,-2 ---------------GUCCAGUUUUCCCAGGAAUCCaa-------------------------------------------------- 43 0,-2 ---------------GUCCAGUUUUCCCAGGAAUCCau-------------------------------------------------- 93 0,-2 ---------------GUCCAGUUUUCCCAGGAAUCCg--------------------------------------------------- 25 0,-2 ---------------GUCCAGUUUUCCCAGGAAUCCu--------------------------------------------------- 81 0,-2 ---------------GUCCAGUUUUCCCAGGAAUCCuu-------------------------------------------------- 91 0,-2 ---------------GUCCAGUUUUCCCAGGAAUCCC--------------------------------------------------- 12027 0,-1 ---------------GUCCAGUUUUCCCAGGAAUCCCa-------------------------------------------------- 2454 0,-1 ---------------GUCCAGUUUUCCCAGGAAUCCCaa------------------------------------------------- 9 0,-1 ---------------GUCCAGUUUUCCCAGGAAUCCCau------------------------------------------------- 101 0,-1 ---------------GUCCAGUUUUCCCAGGAAUCCCc-------------------------------------------------- 151 0,-1 ---------------GUCCAGUUUUCCCAGGAAUCCCg-------------------------------------------------- 107 0,-1 ---------------GUCCAGUUUUCCCAGGAAUCCCU-------------------------------------------------- 43575 0,0 ---------------GUCCAGUUUUCCCAGGAAUCCCUa------------------------------------------------- 138 0,0 ---------------GUCCAGUUUUCCCAGGAAUCCCUaa------------------------------------------------ 3 0,0 ---------------GUCCAGUUUUCCCAGGAAUCCCUau------------------------------------------------ 5 0,0 ---------------GUCCAGUUUUCCCAGGAAUCCCUc------------------------------------------------- 2 0,0 ---------------GUCCAGUUUUCCCAGGAAUCCCUg------------------------------------------------- 11 0,0 ---------------GUCCAGUUUUCCCAGGAAUCCCUU------------------------------------------------- 1481 0,1 ---------------GUCCAGUUUUCCCAGGAAUCCCUUu------------------------------------------------ 84 0,1 ----------------UCCAGUUUUCCCAGGAAUCC---------------------------------------------------- 13 1,-2 ----------------UCCAGUUUUCCCAGGAAUCCau-------------------------------------------------- 2 1,-2 ----------------UCCAGUUUUCCCAGGAAUCCC--------------------------------------------------- 17 1,-1 ----------------UCCAGUUUUCCCAGGAAUCCCa-------------------------------------------------- 2 1,-1 ----------------UCCAGUUUUCCCAGGAAUCCCU-------------------------------------------------- 109 1,0 ----------------UCCAGUUUUCCCAGGAAUCCCUU------------------------------------------------- 8 1,1 -----------------CCAGUUUUCCCAGGAAUCCCU-------------------------------------------------- 15 2,0 -----------------------------------------------------GGAUUCCUGGAAAUACUGUU--------------- 12 0,-2 -----------------------------------------------------GGAUUCCUGGAAAUACUGUUC-------------- 36 0,-1 -----------------------------------------------------GGAUUCCUGGAAAUACUGUUCU------------- 367 0,0 -----------------------------------------------------GGAUUCCUGGAAAUACUGUUCUU------------ 10 0,1 ------------------------------------------------------GAUUCCUGGAAAUACUGUUC-------------- 9 1,-1 ------------------------------------------------------GAUUCCUGGAAAUACUGUUCU------------- 52 1,0 ------------------------------------------------------GAUUCCUGGAAAUACUGUUCUa------------ 7 1,0 ------------------------------------------------------GAUUCCUGGAAAUACUGUUCUau----------- 2 1,0 ------------------------------------------------------GAUUCCUGGAAAUACUGUUCUU------------ 86 1,1 ------------------------------------------------------GAUUCCUGGAAAUACUGUUCUUu----------- 6 1,1 -------------------------------------------------------AUUCCUGGAAAUACUGUU--------------- 5 2,-2 -------------------------------------------------------AUUCCUGGAAAUACUGUUaa------------- 4 2,-2 -------------------------------------------------------AUUCCUGGAAAUACUGUUC-------------- 35 2,-1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCa------------- 5 2,-1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCc------------- 2 2,-1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCU------------- 395 2,0 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUa------------ 116 2,0 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUaa----------- 28 2,0 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUau----------- 17 2,0 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUU------------ 555 2,1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUUa----------- 18 2,1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUUu----------- 32 2,1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUUuu---------- 2 2,1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUUG----------- 2 2,2 >hsa-mir-1468 5pM:13-33 Normal ggugggugguuuCUCCGUUUGCCUGUUUCGCUGaugugcauucaacucauucucagcaaaauaagcaaauggaaaauucguccauc ------------CUCCGUUUGCCUGUUUCGCU------------------------------------------------------ 4 0,-1 ------------CUCCGUUUGCCUGUUUCGCUGA---------------------------------------------------- 15 0,1 ------------CUCCGUUUGCCUGUUUCGCUGAa--------------------------------------------------- 2 0,1 >hsa-mir-146a MA:21-42;mi:57-78 Normal ccgauguguauccucagcuuUGAGAACUGAAUUCCAUGGGUUgugucagugucagaCCUCUGAAAUUCAGUUCUUCAGcugggauaucucugucaucgu -------------------UUGAGAACUGAAUUCCAUGGGU---------------------------------------------------------- 4 -1,-1 --------------------UGAGAACUGAAUUCCAUG------------------------------------------------------------- 14 0,-4 --------------------UGAGAACUGAAUUCCAUGa------------------------------------------------------------ 2 0,-4 --------------------UGAGAACUGAAUUCCAUGG------------------------------------------------------------ 31 0,-3 --------------------UGAGAACUGAAUUCCAUGGa----------------------------------------------------------- 4 0,-3 --------------------UGAGAACUGAAUUCCAUGGaa---------------------------------------------------------- 5 0,-3 --------------------UGAGAACUGAAUUCCAUGGG----------------------------------------------------------- 55 0,-2 --------------------UGAGAACUGAAUUCCAUGGGa---------------------------------------------------------- 50 0,-2 --------------------UGAGAACUGAAUUCCAUGGGaa--------------------------------------------------------- 48 0,-2 --------------------UGAGAACUGAAUUCCAUGGGau--------------------------------------------------------- 8 0,-2 --------------------UGAGAACUGAAUUCCAUGGGc---------------------------------------------------------- 3 0,-2 --------------------UGAGAACUGAAUUCCAUGGGg---------------------------------------------------------- 3 0,-2 --------------------UGAGAACUGAAUUCCAUGGGU---------------------------------------------------------- 764 0,-1 --------------------UGAGAACUGAAUUCCAUGGGUa--------------------------------------------------------- 38 0,-1 --------------------UGAGAACUGAAUUCCAUGGGUaa-------------------------------------------------------- 31 0,-1 --------------------UGAGAACUGAAUUCCAUGGGUau-------------------------------------------------------- 28 0,-1 --------------------UGAGAACUGAAUUCCAUGGGUc--------------------------------------------------------- 4 0,-1 --------------------UGAGAACUGAAUUCCAUGGGUU--------------------------------------------------------- 4002 0,0 --------------------UGAGAACUGAAUUCCAUGGGUUa-------------------------------------------------------- 145 0,0 --------------------UGAGAACUGAAUUCCAUGGGUUaa------------------------------------------------------- 18 0,0 --------------------UGAGAACUGAAUUCCAUGGGUUau------------------------------------------------------- 43 0,0 --------------------UGAGAACUGAAUUCCAUGGGUUu-------------------------------------------------------- 1096 0,0 --------------------UGAGAACUGAAUUCCAUGGGUUuu------------------------------------------------------- 86 0,0 --------------------UGAGAACUGAAUUCCAUGGGUUG-------------------------------------------------------- 185 0,1 --------------------UGAGAACUGAAUUCCAUGGGUUGa------------------------------------------------------- 49 0,1 --------------------UGAGAACUGAAUUCCAUGGGUUGaa------------------------------------------------------ 2 0,1 --------------------UGAGAACUGAAUUCCAUGGGUUGU------------------------------------------------------- 115 0,2 ---------------------GAGAACUGAAUUCCAUGGG----------------------------------------------------------- 2 1,-2 ---------------------GAGAACUGAAUUCCAUGGGU---------------------------------------------------------- 22 1,-1 ---------------------GAGAACUGAAUUCCAUGGGUa--------------------------------------------------------- 2 1,-1 ---------------------GAGAACUGAAUUCCAUGGGUau-------------------------------------------------------- 2 1,-1 ---------------------GAGAACUGAAUUCCAUGGGUU--------------------------------------------------------- 181 1,0 ---------------------GAGAACUGAAUUCCAUGGGUUa-------------------------------------------------------- 4 1,0 ---------------------GAGAACUGAAUUCCAUGGGUUu-------------------------------------------------------- 34 1,0 ---------------------GAGAACUGAAUUCCAUGGGUUuu------------------------------------------------------- 5 1,0 ---------------------GAGAACUGAAUUCCAUGGGUUG-------------------------------------------------------- 11 1,1 ---------------------GAGAACUGAAUUCCAUGGGUUGa------------------------------------------------------- 2 1,1 ---------------------GAGAACUGAAUUCCAUGGGUUGU------------------------------------------------------- 3 1,2 ----------------------AGAACUGAAUUCCAUGGGUU--------------------------------------------------------- 7 2,0 ----------------------AGAACUGAAUUCCAUGGGUUG-------------------------------------------------------- 4 2,1 ----------------------AGAACUGAAUUCCAUGGGUUGa------------------------------------------------------- 2 2,1 ------------------------------------------------------GACCUCUGAAAUUCAGUUCUU------------------------ 2 -2,-3 ------------------------------------------------------GACCUCUGAAAUUCAGUUCUUC----------------------- 2 -2,-2 -------------------------------------------------------ACCUCUGAAAUUCAGUUCUUCA---------------------- 2 -1,-1 ----------------------------------------------------------UCUGAAAUUCAGUUCUUCAGu-------------------- 2 2,0 >hsa-mir-146b 5p:9-30;3p:45-66 Normal ccuggcacUGAGAACUGAAUUCCAUAGGCUgugagcucuagcaaUGCCCUGUGGACUCAGUUCUGGugcccgg -------CUGAGAACUGAAUUCCAU------------------------------------------------ 23 -1,-5 -------CUGAGAACUGAAUUCCAUAGGCUG------------------------------------------ 3 -1,1 -------CUGAGAACUGAAUUCCAUAGGCUGU----------------------------------------- 2 -1,2 --------UGAGAACUGAAUUCCAUA----------------------------------------------- 12 0,-4 --------UGAGAACUGAAUUCCAUAa---------------------------------------------- 2 0,-4 --------UGAGAACUGAAUUCCAUAG---------------------------------------------- 20 0,-3 --------UGAGAACUGAAUUCCAUAGG--------------------------------------------- 127 0,-2 --------UGAGAACUGAAUUCCAUAGGa-------------------------------------------- 64 0,-2 --------UGAGAACUGAAUUCCAUAGGaa------------------------------------------- 33 0,-2 --------UGAGAACUGAAUUCCAUAGGu-------------------------------------------- 2 0,-2 --------UGAGAACUGAAUUCCAUAGGuu------------------------------------------- 12 0,-2 --------UGAGAACUGAAUUCCAUAGGC-------------------------------------------- 142 0,-1 --------UGAGAACUGAAUUCCAUAGGCa------------------------------------------- 47 0,-1 --------UGAGAACUGAAUUCCAUAGGCaa------------------------------------------ 20 0,-1 --------UGAGAACUGAAUUCCAUAGGCau------------------------------------------ 6 0,-1 --------UGAGAACUGAAUUCCAUAGGCU------------------------------------------- 1470 0,0 --------UGAGAACUGAAUUCCAUAGGCUa------------------------------------------ 59 0,0 --------UGAGAACUGAAUUCCAUAGGCUau----------------------------------------- 6 0,0 --------UGAGAACUGAAUUCCAUAGGCUc------------------------------------------ 2 0,0 --------UGAGAACUGAAUUCCAUAGGCUu------------------------------------------ 118 0,0 --------UGAGAACUGAAUUCCAUAGGCUuu----------------------------------------- 2 0,0 --------UGAGAACUGAAUUCCAUAGGCUG------------------------------------------ 862 0,1 --------UGAGAACUGAAUUCCAUAGGCUGa----------------------------------------- 71 0,1 --------UGAGAACUGAAUUCCAUAGGCUGg----------------------------------------- 19 0,1 --------UGAGAACUGAAUUCCAUAGGCUGU----------------------------------------- 597 0,2 --------UGAGAACUGAAUUCCAUAGGCUGUu---------------------------------------- 4 0,2 ---------GAGAACUGAAUUCCAUAG---------------------------------------------- 2 1,-3 ---------GAGAACUGAAUUCCAUAGG--------------------------------------------- 3 1,-2 ---------GAGAACUGAAUUCCAUAGGa-------------------------------------------- 3 1,-2 ---------GAGAACUGAAUUCCAUAGGC-------------------------------------------- 8 1,-1 ---------GAGAACUGAAUUCCAUAGGCU------------------------------------------- 74 1,0 ---------GAGAACUGAAUUCCAUAGGCUG------------------------------------------ 38 1,1 ---------GAGAACUGAAUUCCAUAGGCUGg----------------------------------------- 2 1,1 ---------GAGAACUGAAUUCCAUAGGCUGU----------------------------------------- 20 1,2 --------------------------------------------UGCCCUGUGGACUCAGUUCUGGU------ 6 0,1 ---------------------------------------------GCCCUGUGGACUCAGUUCUGG------- 16 1,0 ---------------------------------------------GCCCUGUGGACUCAGUUCUGGU------ 44 1,1 >hsa-mir-147b 3pM:49-70 Normal uauaaaucuaguggaaacauuucugcacaaacuagauucuggacaccaGUGUGCGGAAAUGCUUCUGCUAcauuuuuagg -----------------------------------------------AGUGUGCGGAAAUGCUUCUGCU----------- 9 -1,-1 ------------------------------------------------GUGUGCGGAAAUGCUUCUGa------------ 2 0,-3 ------------------------------------------------GUGUGCGGAAAUGCUUCUGC------------ 3 0,-2 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCU----------- 45 0,-1 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUu---------- 5 0,-1 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUA---------- 12 0,0 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUAu--------- 2 0,0 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUAC--------- 5 0,1 >hsa-mir-148a mi:6-27;MA:44-65 Normal gaggcAAAGUUCUGAGACACUCCGACUcugaguaugauagaagUCAGUGCACUACAGAACUUUGUcuc ----CAAAGUUCUGAGACACUCCGACU----------------------------------------- 4 -1,0 -----AAAGUUCUGAGACACUCCG-------------------------------------------- 6 0,-3 -----AAAGUUCUGAGACACUCCGc------------------------------------------- 2 0,-3 -----AAAGUUCUGAGACACUCCGA------------------------------------------- 88 0,-2 -----AAAGUUCUGAGACACUCCGAC------------------------------------------ 14 0,-1 -----AAAGUUCUGAGACACUCCGACa----------------------------------------- 11 0,-1 -----AAAGUUCUGAGACACUCCGACU----------------------------------------- 111 0,0 -----AAAGUUCUGAGACACUCCGACUCU--------------------------------------- 2 0,2 ------AAGUUCUGAGACACUCCGACU----------------------------------------- 3 1,0 ------------------------------------------GUCAGUGCACUACAGAACUUUGU--- 2 -1,0 -------------------------------------------UCAGUGCACUACAGAACU------- 211 0,-4 -------------------------------------------UCAGUGCACUACAGAACUU------ 398 0,-3 -------------------------------------------UCAGUGCACUACAGAACUUc----- 3 0,-3 -------------------------------------------UCAGUGCACUACAGAACUUg----- 2 0,-3 -------------------------------------------UCAGUGCACUACAGAACUUU----- 2024 0,-2 -------------------------------------------UCAGUGCACUACAGAACUUUa---- 11 0,-2 -------------------------------------------UCAGUGCACUACAGAACUUUaa--- 2 0,-2 -------------------------------------------UCAGUGCACUACAGAACUUUau--- 26 0,-2 -------------------------------------------UCAGUGCACUACAGAACUUUu---- 36 0,-2 -------------------------------------------UCAGUGCACUACAGAACUUUuu--- 41 0,-2 -------------------------------------------UCAGUGCACUACAGAACUUUG---- 4083 0,-1 -------------------------------------------UCAGUGCACUACAGAACUUUGa--- 720 0,-1 -------------------------------------------UCAGUGCACUACAGAACUUUGaa-- 24 0,-1 -------------------------------------------UCAGUGCACUACAGAACUUUGau-- 6 0,-1 -------------------------------------------UCAGUGCACUACAGAACUUUGc--- 43 0,-1 -------------------------------------------UCAGUGCACUACAGAACUUUGg--- 36 0,-1 -------------------------------------------UCAGUGCACUACAGAACUUUGU--- 23374 0,0 -------------------------------------------UCAGUGCACUACAGAACUUUGUa-- 134 0,0 -------------------------------------------UCAGUGCACUACAGAACUUUGUaa- 15 0,0 -------------------------------------------UCAGUGCACUACAGAACUUUGUau- 5 0,0 -------------------------------------------UCAGUGCACUACAGAACUUUGUg-- 9 0,0 -------------------------------------------UCAGUGCACUACAGAACUUUGUu-- 528 0,0 -------------------------------------------UCAGUGCACUACAGAACUUUGUuu- 31 0,0 -------------------------------------------UCAGUGCACUACAGAACUUUGUC-- 359 0,1 -------------------------------------------UCAGUGCACUACAGAACUUUGUCa- 40 0,1 -------------------------------------------UCAGUGCACUACAGAACUUUGUCU- 98 0,2 --------------------------------------------CAGUGCACUACAGAACUUU----- 6 1,-2 --------------------------------------------CAGUGCACUACAGAACUUUG---- 32 1,-1 --------------------------------------------CAGUGCACUACAGAACUUUGU--- 145 1,0 --------------------------------------------CAGUGCACUACAGAACUUUGUu-- 2 1,0 --------------------------------------------CAGUGCACUACAGAACUUUGUCU- 2 1,2 ---------------------------------------------AGUGCACUACAGAACUUU----- 2 2,-2 ---------------------------------------------AGUGCACUACAGAACUUUG---- 34 2,-1 ---------------------------------------------AGUGCACUACAGAACUUUGa--- 7 2,-1 ---------------------------------------------AGUGCACUACAGAACUUUGU--- 196 2,0 >hsa-mir-148b mi:25-46;MA:63-84 Normal caagcacgauuagcauuugaggugAAGUUCUGUUAUACACUCAGGCuguggcucucugaaagUCAGUGCAUCACAGAACUUUGUcucgaaagcuuucua -----------------------GAAGUUCUGUUAUACACUCAGG------------------------------------------------------ 2 -1,-1 -----------------------GAAGUUCUGUUAUACACUCAGGCU---------------------------------------------------- 2 -1,1 --------------------------------------------------------------UCAGUGCAUCACAGAACU------------------- 2 0,-4 --------------------------------------------------------------UCAGUGCAUCACAGAACUU------------------ 12 0,-3 --------------------------------------------------------------UCAGUGCAUCACAGAACUUU----------------- 58 0,-2 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUau--------------- 4 0,-2 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUu---------------- 4 0,-2 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUuu--------------- 2 0,-2 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUG---------------- 183 0,-1 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGa--------------- 50 0,-1 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGau-------------- 2 0,-1 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGc--------------- 4 0,-1 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGU--------------- 1962 0,0 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGUa-------------- 11 0,0 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGUaa------------- 2 0,0 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGUau------------- 2 0,0 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGUu-------------- 586 0,0 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGUuu------------- 41 0,0 ---------------------------------------------------------------CAGUGCAUCACAGAACUUUGU--------------- 5 1,0 ----------------------------------------------------------------AGUGCAUCACAGAACUUU----------------- 2 2,-2 ----------------------------------------------------------------AGUGCAUCACAGAACUUUG---------------- 2 2,-1 ----------------------------------------------------------------AGUGCAUCACAGAACUUUGU--------------- 10 2,0 >hsa-mir-149 MA:15-37;mi:56-76 Normal gccggcgcccgagcUCUGGCUCCGUGUCUUCACUCCCgugcuuguccgaggagggAGGGAGGGACGGGGGCUGUGCuggggcagcugga --------------UCUGGCUCCGUGUCUUCACU------------------------------------------------------- 25 0,-3 --------------UCUGGCUCCGUGUCUUCACUC------------------------------------------------------ 17 0,-2 --------------UCUGGCUCCGUGUCUUCACUCC----------------------------------------------------- 46 0,-1 --------------UCUGGCUCCGUGUCUUCACUCCu---------------------------------------------------- 2 0,-1 --------------UCUGGCUCCGUGUCUUCACUCCC---------------------------------------------------- 48 0,0 --------------UCUGGCUCCGUGUCUUCACUCCCa--------------------------------------------------- 2 0,0 --------------UCUGGCUCCGUGUCUUCACUCCCu--------------------------------------------------- 5 0,0 >hsa-mir-150 MA:16-37;mi:51-72 Normal cuccccauggcccugUCUCCCAACCCUUGUACCAGUGcugggcucagaccCUGGUACAGGCCUGGGGGACAGggaccuggggac -------------UGUCUCCCAACCCUUGUACCAG------------------------------------------------- 2 -2,-2 -------------UGUCUCCCAACCCUUGUACCAGU------------------------------------------------ 16 -2,-1 ---------------UCUCCCAACCCUUGUACC--------------------------------------------------- 9 0,-4 ---------------UCUCCCAACCCUUGUACCA-------------------------------------------------- 9 0,-3 ---------------UCUCCCAACCCUUGUACCAG------------------------------------------------- 29 0,-2 ---------------UCUCCCAACCCUUGUACCAGa------------------------------------------------ 3 0,-2 ---------------UCUCCCAACCCUUGUACCAGc------------------------------------------------ 4 0,-2 ---------------UCUCCCAACCCUUGUACCAGU------------------------------------------------ 448 0,-1 ---------------UCUCCCAACCCUUGUACCAGUa----------------------------------------------- 12 0,-1 ---------------UCUCCCAACCCUUGUACCAGUu----------------------------------------------- 2 0,-1 ---------------UCUCCCAACCCUUGUACCAGUG----------------------------------------------- 1033 0,0 ---------------UCUCCCAACCCUUGUACCAGUGa---------------------------------------------- 265 0,0 ---------------UCUCCCAACCCUUGUACCAGUGu---------------------------------------------- 133 0,0 ---------------UCUCCCAACCCUUGUACCAGUGC---------------------------------------------- 5 0,1 ----------------CUCCCAACCCUUGUACCAGU------------------------------------------------ 2 1,-1 ----------------CUCCCAACCCUUGUACCAGUG----------------------------------------------- 5 1,0 -----------------UCCCAACCCUUGUACCAGUG----------------------------------------------- 4 2,0 --------------------------------------------------CUGGUACAGGCCUGGGGGAC-------------- 4 0,-2 --------------------------------------------------CUGGUACAGGCCUGGGGGACA------------- 4 0,-1 >hsa-mir-151 5p:11-31;3p:47-67 Normal uuuccugcccUCGAGGAGCUCACAGUCUAGUaugucucauccccuaCUAGACUGAAGCUCCUUGAGGacagggauggucauacucaccuc ---------CUCGAGGAGCUCACAGUCU-------------------------------------------------------------- 2 -1,-3 ---------CUCGAGGAGCUCACAGUCUAG------------------------------------------------------------ 4 -1,-1 ---------CUCGAGGAGCUCACAGUCUAGU----------------------------------------------------------- 76 -1,0 ---------CUCGAGGAGCUCACAGUCUAGUA---------------------------------------------------------- 7 -1,1 ----------UCGAGGAGCUCACAGUCU-------------------------------------------------------------- 26 0,-3 ----------UCGAGGAGCUCACAGUCUA------------------------------------------------------------- 4 0,-2 ----------UCGAGGAGCUCACAGUCUAa------------------------------------------------------------ 4 0,-2 ----------UCGAGGAGCUCACAGUCUAaa----------------------------------------------------------- 2 0,-2 ----------UCGAGGAGCUCACAGUCUAau----------------------------------------------------------- 5 0,-2 ----------UCGAGGAGCUCACAGUCUAG------------------------------------------------------------ 177 0,-1 ----------UCGAGGAGCUCACAGUCUAGc----------------------------------------------------------- 2 0,-1 ----------UCGAGGAGCUCACAGUCUAGU----------------------------------------------------------- 1930 0,0 ----------UCGAGGAGCUCACAGUCUAGUu---------------------------------------------------------- 2 0,0 ----------UCGAGGAGCUCACAGUCUAGUA---------------------------------------------------------- 184 0,1 ----------UCGAGGAGCUCACAGUCUAGUAa--------------------------------------------------------- 113 0,1 ----------UCGAGGAGCUCACAGUCUAGUAaa-------------------------------------------------------- 5 0,1 ----------UCGAGGAGCUCACAGUCUAGUAg--------------------------------------------------------- 2 0,1 ----------UCGAGGAGCUCACAGUCUAGUAU--------------------------------------------------------- 19 0,2 -----------CGAGGAGCUCACAGUCUAG------------------------------------------------------------ 2 1,-1 -----------CGAGGAGCUCACAGUCUAGU----------------------------------------------------------- 48 1,0 ------------GAGGAGCUCACAGUCUAGU----------------------------------------------------------- 24 2,0 --------------------------------------------UACUAGACUGAAGCUCCUUGA------------------------- 6 -2,-2 --------------------------------------------UACUAGACUGAAGCUCCUUGAG------------------------ 21 -2,-1 --------------------------------------------UACUAGACUGAAGCUCCUUGAGa----------------------- 2 -2,-1 --------------------------------------------UACUAGACUGAAGCUCCUUGAGG----------------------- 13 -2,0 ---------------------------------------------ACUAGACUGAAGCUCCUUGA------------------------- 4 -1,-2 ---------------------------------------------ACUAGACUGAAGCUCCUUGAG------------------------ 11 -1,-1 ---------------------------------------------ACUAGACUGAAGCUCCUUGAGu----------------------- 4 -1,-1 ---------------------------------------------ACUAGACUGAAGCUCCUUGAGG----------------------- 25 -1,0 ---------------------------------------------ACUAGACUGAAGCUCCUUGAGGA---------------------- 2 -1,1 ----------------------------------------------CUAGACUGAAGCUCCUUG-------------------------- 20 0,-3 ----------------------------------------------CUAGACUGAAGCUCCUUGu------------------------- 2 0,-3 ----------------------------------------------CUAGACUGAAGCUCCUUGA------------------------- 71 0,-2 ----------------------------------------------CUAGACUGAAGCUCCUUGAa------------------------ 19 0,-2 ----------------------------------------------CUAGACUGAAGCUCCUUGAaa----------------------- 12 0,-2 ----------------------------------------------CUAGACUGAAGCUCCUUGAau----------------------- 2 0,-2 ----------------------------------------------CUAGACUGAAGCUCCUUGAu------------------------ 4 0,-2 ----------------------------------------------CUAGACUGAAGCUCCUUGAG------------------------ 518 0,-1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGa----------------------- 237 0,-1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGaa---------------------- 54 0,-1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGu----------------------- 230 0,-1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGuu---------------------- 16 0,-1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGG----------------------- 827 0,0 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGu---------------------- 257 0,0 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGuu--------------------- 30 0,0 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGA---------------------- 500 0,1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGAa--------------------- 372 0,1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGAaa-------------------- 29 0,1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGAau-------------------- 24 0,1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGAg--------------------- 22 0,1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGAu--------------------- 63 0,1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGAuu-------------------- 4 0,1 -----------------------------------------------UAGACUGAAGCUCCUUGAG------------------------ 13 1,-1 -----------------------------------------------UAGACUGAAGCUCCUUGAGa----------------------- 5 1,-1 -----------------------------------------------UAGACUGAAGCUCCUUGAGaa---------------------- 2 1,-1 -----------------------------------------------UAGACUGAAGCUCCUUGAGau---------------------- 2 1,-1 -----------------------------------------------UAGACUGAAGCUCCUUGAGu----------------------- 4 1,-1 -----------------------------------------------UAGACUGAAGCUCCUUGAGG----------------------- 25 1,0 -----------------------------------------------UAGACUGAAGCUCCUUGAGGu---------------------- 2 1,0 -----------------------------------------------UAGACUGAAGCUCCUUGAGGA---------------------- 9 1,1 -----------------------------------------------UAGACUGAAGCUCCUUGAGGAa--------------------- 11 1,1 -----------------------------------------------UAGACUGAAGCUCCUUGAGGAu--------------------- 2 1,1 ------------------------------------------------AGACUGAAGCUCCUUGAGG----------------------- 2 2,0 ------------------------------------------------AGACUGAAGCUCCUUGAGGACu-------------------- 2 2,2 >hsa-mir-151b 3pM:60-77 Normal accucugaugugucagucucucuucagggcucccgagacacagaaacagacaccugcccUCGAGGAGCUCACAGUCUagacaaacaaacccagggu ----------------------------------------------------------CUCGAGGAGCUCACAGUCU------------------- 2 -1,0 ----------------------------------------------------------CUCGAGGAGCUCACAGUCUAG----------------- 4 -1,2 -----------------------------------------------------------UCGAGGAGCUCACAGUCU------------------- 26 0,0 -----------------------------------------------------------UCGAGGAGCUCACAGUCUA------------------ 4 0,1 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAa----------------- 4 0,1 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAaa---------------- 2 0,1 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAau---------------- 5 0,1 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAG----------------- 177 0,2 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAGc---------------- 2 0,2 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAGA---------------- 22 0,3 ------------------------------------------------------------CGAGGAGCUCACAGUCUAG----------------- 2 1,2 >hsa-mir-152 3pM:54-74 Normal ugucccccccggcccagguucugugauacacuccgacucgggcucuggagcagUCAGUGCAUGACAGAACUUGGgcccggaaggacc ----------------------------------------------------GUCAGUGCAUGACAGAACUUGu------------- 2 -1,-1 ----------------------------------------------------GUCAGUGCAUGACAGAACUUGG------------- 12 -1,0 ----------------------------------------------------GUCAGUGCAUGACAGAACUUGGa------------ 2 -1,0 ----------------------------------------------------GUCAGUGCAUGACAGAACUUGGu------------ 2 -1,0 -----------------------------------------------------UCAGUGCAUGACAGAACU---------------- 9 0,-3 -----------------------------------------------------UCAGUGCAUGACAGAACUU--------------- 23 0,-2 -----------------------------------------------------UCAGUGCAUGACAGAACUUu-------------- 2 0,-2 -----------------------------------------------------UCAGUGCAUGACAGAACUUG-------------- 140 0,-1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGa------------- 11 0,-1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGau------------ 3 0,-1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGu------------- 46 0,-1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGuu------------ 2 0,-1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGG------------- 1260 0,0 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGa------------ 249 0,0 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGaa----------- 31 0,0 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGu------------ 444 0,0 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGuu----------- 28 0,0 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGG------------ 404 0,1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGGa----------- 253 0,1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGGaa---------- 15 0,1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGGau---------- 5 0,1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGGu----------- 514 0,1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGGuu---------- 28 0,1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGGC----------- 2 0,2 ------------------------------------------------------CAGUGCAUGACAGAACUUGG------------- 9 1,0 -------------------------------------------------------AGUGCAUGACAGAACUUGG------------- 11 2,0 -------------------------------------------------------AGUGCAUGACAGAACUUGGu------------ 2 2,0 -------------------------------------------------------AGUGCAUGACAGAACUUGGG------------ 2 2,1 -------------------------------------------------------AGUGCAUGACAGAACUUGGGa----------- 2 2,1 >hsa-mir-153-1 3pM:54-75 Normal cucacagcugccagugucauuuuugugaucugcagcuaguauucucacuccagUUGCAUAGUCACAAAAGUGAUCauuggcagguguggc ---------------GUCAUUUUUGUGAUCUGCAGCUA---------------------------------------------------- 2 -----------------------------------------------------UUGCAUAGUCACAAAAGUGA----------------- 14 0,-2 -----------------------------------------------------UUGCAUAGUCACAAAAGUGAU---------------- 49 0,-1 -----------------------------------------------------UUGCAUAGUCACAAAAGUGAUa--------------- 2 0,-1 -----------------------------------------------------UUGCAUAGUCACAAAAGUGAUaa-------------- 3 0,-1 -----------------------------------------------------UUGCAUAGUCACAAAAGUGAUC--------------- 71 0,0 -----------------------------------------------------UUGCAUAGUCACAAAAGUGAUCA-------------- 16 0,1 -----------------------------------------------------UUGCAUAGUCACAAAAGUGAUCAU------------- 2 0,2 ------------------------------------------------------UGCAUAGUCACAAAAGUGAUCA-------------- 2 1,1 ------------------------------------------------------UGCAUAGUCACAAAAGUGAUCAU------------- 2 1,2 >hsa-mir-153-2 3pM:53-74 Normal agcgguggccagugucauuuuugugauguugcagcuaguaauaugagcccagUUGCAUAGUCACAAAAGUGAUCauuggaaacugug ----------------------------------------------------UUGCAUAGUCACAAAAGUGA--------------- 14 0,-2 ----------------------------------------------------UUGCAUAGUCACAAAAGUGAU-------------- 49 0,-1 ----------------------------------------------------UUGCAUAGUCACAAAAGUGAUa------------- 2 0,-1 ----------------------------------------------------UUGCAUAGUCACAAAAGUGAUaa------------ 3 0,-1 ----------------------------------------------------UUGCAUAGUCACAAAAGUGAUC------------- 71 0,0 ----------------------------------------------------UUGCAUAGUCACAAAAGUGAUCA------------ 16 0,1 ----------------------------------------------------UUGCAUAGUCACAAAAGUGAUCAU----------- 2 0,2 -----------------------------------------------------UGCAUAGUCACAAAAGUGAUCA------------ 2 1,1 -----------------------------------------------------UGCAUAGUCACAAAAGUGAUCAU----------- 2 1,2 >hsa-mir-154 MA:15-36;mi:51-72 Normal gugguacuugaagaUAGGUUAUCCGUGUUGCCUUCGcuuuauuugugacgAAUCAUACACGGUUGACCUAUUuuucaguaccaa --------------UAGGUUAUCCGUGUUGCCUUC------------------------------------------------- 4 0,-1 --------------UAGGUUAUCCGUGUUGCCUUCG------------------------------------------------ 47 0,0 --------------UAGGUUAUCCGUGUUGCCUUCGa----------------------------------------------- 4 0,0 --------------UAGGUUAUCCGUGUUGCCUUCGu----------------------------------------------- 2 0,0 ---------------AGGUUAUCCGUGUUGCCUUCG------------------------------------------------ 2 1,0 --------------------------------------------------AAUCAUACACGGUUGACCUAU------------- 2 0,-1 --------------------------------------------------AAUCAUACACGGUUGACCUAUU------------ 23 0,0 >hsa-mir-155 MA:4-26;mi:43-64 Normal cugUUAAUGCUAAUCGUGAUAGGGGUuuuugccuccaacugaCUCCUACAUAUUAGCAUUAACAg ---UUAAUGCUAAUCGUGAUAGG------------------------------------------ 9 0,-3 ---UUAAUGCUAAUCGUGAUAGGa----------------------------------------- 2 0,-3 ---UUAAUGCUAAUCGUGAUAGGG----------------------------------------- 12 0,-2 ---UUAAUGCUAAUCGUGAUAGGGa---------------------------------------- 6 0,-2 ---UUAAUGCUAAUCGUGAUAGGGaa--------------------------------------- 2 0,-2 ---UUAAUGCUAAUCGUGAUAGGGG---------------------------------------- 12 0,-1 ---UUAAUGCUAAUCGUGAUAGGGGa--------------------------------------- 4 0,-1 ---UUAAUGCUAAUCGUGAUAGGGGU--------------------------------------- 40 0,0 ---UUAAUGCUAAUCGUGAUAGGGGUU-------------------------------------- 9 0,1 ---UUAAUGCUAAUCGUGAUAGGGGUUU------------------------------------- 2 0,2 >hsa-mir-15a MA:14-35;mi:51-72 Normal ccuuggaguaaagUAGCAGCACAUAAUGGUUUGUGgauuuugaaaaggugCAGGCCAUAUUGUGCUGCCUCAaaaauacaagg -------------UAGCAGCACAUAAUGGUU---------------------------------------------------- 10 0,-4 -------------UAGCAGCACAUAAUGGUUU--------------------------------------------------- 33 0,-3 -------------UAGCAGCACAUAAUGGUUUG-------------------------------------------------- 229 0,-2 -------------UAGCAGCACAUAAUGGUUUGa------------------------------------------------- 7 0,-2 -------------UAGCAGCACAUAAUGGUUUGU------------------------------------------------- 708 0,-1 -------------UAGCAGCACAUAAUGGUUUGUa------------------------------------------------ 2 0,-1 -------------UAGCAGCACAUAAUGGUUUGUaa----------------------------------------------- 4 0,-1 -------------UAGCAGCACAUAAUGGUUUGUu------------------------------------------------ 2 0,-1 -------------UAGCAGCACAUAAUGGUUUGUG------------------------------------------------ 196 0,0 -------------UAGCAGCACAUAAUGGUUUGUGa----------------------------------------------- 402 0,0 -------------UAGCAGCACAUAAUGGUUUGUGaa---------------------------------------------- 2 0,0 -------------UAGCAGCACAUAAUGGUUUGUGc----------------------------------------------- 2 0,0 -------------UAGCAGCACAUAAUGGUUUGUGu----------------------------------------------- 230 0,0 -------------UAGCAGCACAUAAUGGUUUGUGG----------------------------------------------- 59 0,1 -------------UAGCAGCACAUAAUGGUUUGUGGA---------------------------------------------- 72 0,2 -------------UAGCAGCACAUAAUGGUUUGUGGAa--------------------------------------------- 5 0,2 --------------AGCAGCACAUAAUGGUUUG-------------------------------------------------- 6 1,-2 --------------AGCAGCACAUAAUGGUUUGU------------------------------------------------- 9 1,-1 --------------AGCAGCACAUAAUGGUUUGUG------------------------------------------------ 8 1,0 --------------AGCAGCACAUAAUGGUUUGUGa----------------------------------------------- 8 1,0 --------------AGCAGCACAUAAUGGUUUGUGu----------------------------------------------- 12 1,0 ---------------GCAGCACAUAAUGGUUUGU------------------------------------------------- 2 2,-1 --------------------------------------------------CAGGCCAUAUUGUGCUGCCUCA----------- 2 0,0 >hsa-mir-15b MA:20-41;mi:58-79 Normal uugaggccuuaaaguacugUAGCAGCACAUCAUGGUUUACAugcuacagucaagaugCGAAUCAUUAUUUGCUGCUCUAgaaauuuaaggaaauucau -------------------UAGCAGCACAUCAUGGUU------------------------------------------------------------- 72 0,-4 -------------------UAGCAGCACAUCAUGGUUU------------------------------------------------------------ 210 0,-3 -------------------UAGCAGCACAUCAUGGUUUA----------------------------------------------------------- 183 0,-2 -------------------UAGCAGCACAUCAUGGUUUAa---------------------------------------------------------- 16 0,-2 -------------------UAGCAGCACAUCAUGGUUUAu---------------------------------------------------------- 3 0,-2 -------------------UAGCAGCACAUCAUGGUUUAC---------------------------------------------------------- 131 0,-1 -------------------UAGCAGCACAUCAUGGUUUACA--------------------------------------------------------- 368 0,0 -------------------UAGCAGCACAUCAUGGUUUACAa-------------------------------------------------------- 9 0,0 --------------------AGCAGCACAUCAUGGUUU------------------------------------------------------------ 3 1,-3 --------------------AGCAGCACAUCAUGGUUUA----------------------------------------------------------- 2 1,-2 --------------------AGCAGCACAUCAUGGUUUAC---------------------------------------------------------- 3 1,-1 --------------------AGCAGCACAUCAUGGUUUACA--------------------------------------------------------- 11 1,0 ---------------------------------------------------------CGAAUCAUUAUUUGCUGCU---------------------- 29 0,-3 ---------------------------------------------------------CGAAUCAUUAUUUGCUGCUC--------------------- 4 0,-2 ---------------------------------------------------------CGAAUCAUUAUUUGCUGCUCU-------------------- 12 0,-1 ---------------------------------------------------------CGAAUCAUUAUUUGCUGCUCUAu------------------ 2 0,0 ----------------------------------------------------------GAAUCAUUAUUUGCUGCU---------------------- 5 1,-3 >hsa-mir-16-1 MA:14-35;mi:56-77 Normal gucagcagugccuUAGCAGCACGUAAAUAUUGGCGuuaagauucuaaaauuaucuCCAGUAUUAACUGUGCUGCUGAaguaagguugac -------------UAGCAGCACGUAAAUAUU---------------------------------------------------------- 47 0,-4 -------------UAGCAGCACGUAAAUAUUG--------------------------------------------------------- 52 0,-3 -------------UAGCAGCACGUAAAUAUUGa-------------------------------------------------------- 8 0,-3 -------------UAGCAGCACGUAAAUAUUGu-------------------------------------------------------- 2 0,-3 -------------UAGCAGCACGUAAAUAUUGG-------------------------------------------------------- 577 0,-2 -------------UAGCAGCACGUAAAUAUUGGa------------------------------------------------------- 54 0,-2 -------------UAGCAGCACGUAAAUAUUGGaa------------------------------------------------------ 6 0,-2 -------------UAGCAGCACGUAAAUAUUGGu------------------------------------------------------- 4 0,-2 -------------UAGCAGCACGUAAAUAUUGGC------------------------------------------------------- 239 0,-1 -------------UAGCAGCACGUAAAUAUUGGCa------------------------------------------------------ 45 0,-1 -------------UAGCAGCACGUAAAUAUUGGCaa----------------------------------------------------- 13 0,-1 -------------UAGCAGCACGUAAAUAUUGGCau----------------------------------------------------- 2 0,-1 -------------UAGCAGCACGUAAAUAUUGGCc------------------------------------------------------ 2 0,-1 -------------UAGCAGCACGUAAAUAUUGGCu------------------------------------------------------ 6 0,-1 -------------UAGCAGCACGUAAAUAUUGGCG------------------------------------------------------ 2077 0,0 -------------UAGCAGCACGUAAAUAUUGGCGa----------------------------------------------------- 309 0,0 -------------UAGCAGCACGUAAAUAUUGGCGaa---------------------------------------------------- 4 0,0 -------------UAGCAGCACGUAAAUAUUGGCGc----------------------------------------------------- 2 0,0 -------------UAGCAGCACGUAAAUAUUGGCGU----------------------------------------------------- 202 0,1 -------------UAGCAGCACGUAAAUAUUGGCGUU---------------------------------------------------- 17 0,2 -------------UAGCAGCACGUAAAUAUUGGCGUUu--------------------------------------------------- 2 0,2 -------------UAGCAGCACGUAAAUAUUGGCGUUA--------------------------------------------------- 2 0,3 --------------AGCAGCACGUAAAUAUUG--------------------------------------------------------- 2 1,-3 --------------AGCAGCACGUAAAUAUUGG-------------------------------------------------------- 25 1,-2 --------------AGCAGCACGUAAAUAUUGGC------------------------------------------------------- 7 1,-1 --------------AGCAGCACGUAAAUAUUGGCa------------------------------------------------------ 2 1,-1 --------------AGCAGCACGUAAAUAUUGGCG------------------------------------------------------ 92 1,0 --------------AGCAGCACGUAAAUAUUGGCGa----------------------------------------------------- 15 1,0 --------------AGCAGCACGUAAAUAUUGGCGU----------------------------------------------------- 7 1,1 ---------------GCAGCACGUAAAUAUUGG-------------------------------------------------------- 2 2,-2 ---------------GCAGCACGUAAAUAUUGGCG------------------------------------------------------ 9 2,0 ---------------GCAGCACGUAAAUAUUGGCGa----------------------------------------------------- 2 2,0 -------------------------------------------------------CCAGUAUUAACUGUGCUGCUGA------------ 26 0,0 -------------------------------------------------------CCAGUAUUAACUGUGCUGCUGAA----------- 7 0,1 >hsa-mir-16-2 MA:10-31;mi:53-74 Normal guuccacucUAGCAGCACGUAAAUAUUGGCGuagugaaauauauauuaaacaCCAAUAUUACUGUGCUGCUUUAgugugac --------CUAGCAGCACGUAAAUAUUGG---------------------------------------------------- 3 -1,-2 --------CUAGCAGCACGUAAAUAUUGGCG-------------------------------------------------- 9 -1,0 ---------UAGCAGCACGUAAAUAUU------------------------------------------------------ 47 0,-4 ---------UAGCAGCACGUAAAUAUUG----------------------------------------------------- 52 0,-3 ---------UAGCAGCACGUAAAUAUUGa---------------------------------------------------- 8 0,-3 ---------UAGCAGCACGUAAAUAUUGu---------------------------------------------------- 2 0,-3 ---------UAGCAGCACGUAAAUAUUGG---------------------------------------------------- 577 0,-2 ---------UAGCAGCACGUAAAUAUUGGa--------------------------------------------------- 54 0,-2 ---------UAGCAGCACGUAAAUAUUGGaa-------------------------------------------------- 6 0,-2 ---------UAGCAGCACGUAAAUAUUGGu--------------------------------------------------- 4 0,-2 ---------UAGCAGCACGUAAAUAUUGGC--------------------------------------------------- 239 0,-1 ---------UAGCAGCACGUAAAUAUUGGCa-------------------------------------------------- 45 0,-1 ---------UAGCAGCACGUAAAUAUUGGCaa------------------------------------------------- 13 0,-1 ---------UAGCAGCACGUAAAUAUUGGCau------------------------------------------------- 2 0,-1 ---------UAGCAGCACGUAAAUAUUGGCc-------------------------------------------------- 2 0,-1 ---------UAGCAGCACGUAAAUAUUGGCu-------------------------------------------------- 6 0,-1 ---------UAGCAGCACGUAAAUAUUGGCG-------------------------------------------------- 2077 0,0 ---------UAGCAGCACGUAAAUAUUGGCGa------------------------------------------------- 309 0,0 ---------UAGCAGCACGUAAAUAUUGGCGaa------------------------------------------------ 4 0,0 ---------UAGCAGCACGUAAAUAUUGGCGc------------------------------------------------- 2 0,0 ---------UAGCAGCACGUAAAUAUUGGCGU------------------------------------------------- 202 0,1 ---------UAGCAGCACGUAAAUAUUGGCGUA------------------------------------------------ 2 0,2 ----------AGCAGCACGUAAAUAUUG----------------------------------------------------- 2 1,-3 ----------AGCAGCACGUAAAUAUUGG---------------------------------------------------- 25 1,-2 ----------AGCAGCACGUAAAUAUUGGC--------------------------------------------------- 7 1,-1 ----------AGCAGCACGUAAAUAUUGGCa-------------------------------------------------- 2 1,-1 ----------AGCAGCACGUAAAUAUUGGCG-------------------------------------------------- 92 1,0 ----------AGCAGCACGUAAAUAUUGGCGa------------------------------------------------- 15 1,0 ----------AGCAGCACGUAAAUAUUGGCGU------------------------------------------------- 7 1,1 -----------GCAGCACGUAAAUAUUGG---------------------------------------------------- 2 2,-2 -----------GCAGCACGUAAAUAUUGGCG-------------------------------------------------- 9 2,0 -----------GCAGCACGUAAAUAUUGGCGa------------------------------------------------- 2 2,0 ---------------------------------------------------ACCAAUAUUACUGUGCUGC----------- 2 -1,-4 ---------------------------------------------------ACCAAUAUUACUGUGCUGCU---------- 173 -1,-3 ---------------------------------------------------ACCAAUAUUACUGUGCUGCUU--------- 45 -1,-2 ---------------------------------------------------ACCAAUAUUACUGUGCUGCUUU-------- 51 -1,-1 ----------------------------------------------------CCAAUAUUACUGUGCUGCU---------- 2 0,-3 ----------------------------------------------------CCAAUAUUACUGUGCUGCUU--------- 4 0,-2 ----------------------------------------------------CCAAUAUUACUGUGCUGCUUU-------- 2 0,-1 -----------------------------------------------------CAAUAUUACUGUGCUGCU---------- 2 1,-3 >hsa-mir-17 MA:14-36;mi:51-72 Normal gucagaauaauguCAAAGUGCUUACAGUGCAGGUAGugauaugugcaucuACUGCAGUGAAGGCACUUGUAGcauuauggugac ------------UCAAAGUGCUUACAGUGCAG---------------------------------------------------- 7 -1,-4 ------------UCAAAGUGCUUACAGUGCAGG--------------------------------------------------- 26 -1,-3 ------------UCAAAGUGCUUACAGUGCAGGa-------------------------------------------------- 16 -1,-3 ------------UCAAAGUGCUUACAGUGCAGGaa------------------------------------------------- 2 -1,-3 ------------UCAAAGUGCUUACAGUGCAGGau------------------------------------------------- 2 -1,-3 ------------UCAAAGUGCUUACAGUGCAGGU-------------------------------------------------- 103 -1,-2 ------------UCAAAGUGCUUACAGUGCAGGUu------------------------------------------------- 10 -1,-2 ------------UCAAAGUGCUUACAGUGCAGGUuu------------------------------------------------ 3 -1,-2 ------------UCAAAGUGCUUACAGUGCAGGUA------------------------------------------------- 32 -1,-1 ------------UCAAAGUGCUUACAGUGCAGGUAa------------------------------------------------ 4 -1,-1 ------------UCAAAGUGCUUACAGUGCAGGUAu------------------------------------------------ 7 -1,-1 ------------UCAAAGUGCUUACAGUGCAGGUAG------------------------------------------------ 9 -1,0 -------------CAAAGUGCUUACAGUGCA----------------------------------------------------- 12 0,-5 -------------CAAAGUGCUUACAGUGCAa---------------------------------------------------- 4 0,-5 -------------CAAAGUGCUUACAGUGCAG---------------------------------------------------- 83 0,-4 -------------CAAAGUGCUUACAGUGCAGa--------------------------------------------------- 4 0,-4 -------------CAAAGUGCUUACAGUGCAGaa-------------------------------------------------- 2 0,-4 -------------CAAAGUGCUUACAGUGCAGc--------------------------------------------------- 2 0,-4 -------------CAAAGUGCUUACAGUGCAGG--------------------------------------------------- 181 0,-3 -------------CAAAGUGCUUACAGUGCAGGa-------------------------------------------------- 40 0,-3 -------------CAAAGUGCUUACAGUGCAGGaa------------------------------------------------- 41 0,-3 -------------CAAAGUGCUUACAGUGCAGGau------------------------------------------------- 6 0,-3 -------------CAAAGUGCUUACAGUGCAGGc-------------------------------------------------- 2 0,-3 -------------CAAAGUGCUUACAGUGCAGGg-------------------------------------------------- 2 0,-3 -------------CAAAGUGCUUACAGUGCAGGU-------------------------------------------------- 861 0,-2 -------------CAAAGUGCUUACAGUGCAGGUg------------------------------------------------- 3 0,-2 -------------CAAAGUGCUUACAGUGCAGGUu------------------------------------------------- 49 0,-2 -------------CAAAGUGCUUACAGUGCAGGUuu------------------------------------------------ 21 0,-2 -------------CAAAGUGCUUACAGUGCAGGUA------------------------------------------------- 614 0,-1 -------------CAAAGUGCUUACAGUGCAGGUAa------------------------------------------------ 365 0,-1 -------------CAAAGUGCUUACAGUGCAGGUAaa----------------------------------------------- 8 0,-1 -------------CAAAGUGCUUACAGUGCAGGUAau----------------------------------------------- 7 0,-1 -------------CAAAGUGCUUACAGUGCAGGUAc------------------------------------------------ 5 0,-1 -------------CAAAGUGCUUACAGUGCAGGUAu------------------------------------------------ 324 0,-1 -------------CAAAGUGCUUACAGUGCAGGUAG------------------------------------------------ 2017 0,0 -------------CAAAGUGCUUACAGUGCAGGUAGa----------------------------------------------- 267 0,0 -------------CAAAGUGCUUACAGUGCAGGUAGaa---------------------------------------------- 17 0,0 -------------CAAAGUGCUUACAGUGCAGGUAGU----------------------------------------------- 132 0,1 --------------AAAGUGCUUACAGUGCAG---------------------------------------------------- 4 1,-4 --------------AAAGUGCUUACAGUGCAGGU-------------------------------------------------- 27 1,-2 --------------AAAGUGCUUACAGUGCAGGUA------------------------------------------------- 32 1,-1 --------------AAAGUGCUUACAGUGCAGGUAa------------------------------------------------ 16 1,-1 --------------AAAGUGCUUACAGUGCAGGUAu------------------------------------------------ 12 1,-1 --------------AAAGUGCUUACAGUGCAGGUAG------------------------------------------------ 79 1,0 --------------AAAGUGCUUACAGUGCAGGUAGa----------------------------------------------- 16 1,0 --------------AAAGUGCUUACAGUGCAGGUAGU----------------------------------------------- 8 1,1 --------------------------------------------------ACUGCAGUGAAGGCACUUG--------------- 2 0,-3 --------------------------------------------------ACUGCAGUGAAGGCACUUGaa------------- 2 0,-3 --------------------------------------------------ACUGCAGUGAAGGCACUUGU-------------- 20 0,-2 --------------------------------------------------ACUGCAGUGAAGGCACUUGUA------------- 7 0,-1 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAa------------ 9 0,-1 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAu------------ 4 0,-1 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAG------------ 420 0,0 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGa----------- 221 0,0 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGaa---------- 11 0,0 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGg----------- 2 0,0 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGu----------- 75 0,0 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGC----------- 196 0,1 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGCu---------- 4 0,1 ---------------------------------------------------CUGCAGUGAAGGCACUUGUAG------------ 6 1,0 ---------------------------------------------------CUGCAGUGAAGGCACUUGUAGa----------- 4 1,0 ---------------------------------------------------CUGCAGUGAAGGCACUUGUAGu----------- 2 1,0 ---------------------------------------------------CUGCAGUGAAGGCACUUGUAGC----------- 9 1,1 >hsa-mir-181a-1 MA:24-46;mi:64-85 Normal ugaguuuugagguugcuucagugAACAUUCAACGCUGUCGGUGAGUuuggaauuaaaaucaaaACCAUCGACCGUUGAUUGUACCcuauggcuaaccaucaucuacucca -----------------------AACAUUCAACGCUGUCGG--------------------------------------------------------------------- 143 0,-5 -----------------------AACAUUCAACGCUGUCGGa-------------------------------------------------------------------- 8 0,-5 -----------------------AACAUUCAACGCUGUCGGc-------------------------------------------------------------------- 2 0,-5 -----------------------AACAUUCAACGCUGUCGGU-------------------------------------------------------------------- 243 0,-4 -----------------------AACAUUCAACGCUGUCGGUa------------------------------------------------------------------- 19 0,-4 -----------------------AACAUUCAACGCUGUCGGUaa------------------------------------------------------------------ 15 0,-4 -----------------------AACAUUCAACGCUGUCGGUau------------------------------------------------------------------ 2 0,-4 -----------------------AACAUUCAACGCUGUCGGUu------------------------------------------------------------------- 12 0,-4 -----------------------AACAUUCAACGCUGUCGGUG------------------------------------------------------------------- 359 0,-3 -----------------------AACAUUCAACGCUGUCGGUGc------------------------------------------------------------------ 4 0,-3 -----------------------AACAUUCAACGCUGUCGGUGu------------------------------------------------------------------ 124 0,-3 -----------------------AACAUUCAACGCUGUCGGUGuu----------------------------------------------------------------- 5 0,-3 -----------------------AACAUUCAACGCUGUCGGUGA------------------------------------------------------------------ 1304 0,-2 -----------------------AACAUUCAACGCUGUCGGUGAa----------------------------------------------------------------- 262 0,-2 -----------------------AACAUUCAACGCUGUCGGUGAaa---------------------------------------------------------------- 53 0,-2 -----------------------AACAUUCAACGCUGUCGGUGAau---------------------------------------------------------------- 31 0,-2 -----------------------AACAUUCAACGCUGUCGGUGAc----------------------------------------------------------------- 2 0,-2 -----------------------AACAUUCAACGCUGUCGGUGAu----------------------------------------------------------------- 34 0,-2 -----------------------AACAUUCAACGCUGUCGGUGAuu---------------------------------------------------------------- 14 0,-2 -----------------------AACAUUCAACGCUGUCGGUGAG----------------------------------------------------------------- 1377 0,-1 -----------------------AACAUUCAACGCUGUCGGUGAGa---------------------------------------------------------------- 921 0,-1 -----------------------AACAUUCAACGCUGUCGGUGAGaa--------------------------------------------------------------- 19 0,-1 -----------------------AACAUUCAACGCUGUCGGUGAGau--------------------------------------------------------------- 7 0,-1 -----------------------AACAUUCAACGCUGUCGGUGAGc---------------------------------------------------------------- 34 0,-1 -----------------------AACAUUCAACGCUGUCGGUGAGg---------------------------------------------------------------- 21 0,-1 -----------------------AACAUUCAACGCUGUCGGUGAGU---------------------------------------------------------------- 6649 0,0 -----------------------AACAUUCAACGCUGUCGGUGAGUa--------------------------------------------------------------- 15 0,0 -----------------------AACAUUCAACGCUGUCGGUGAGUaa-------------------------------------------------------------- 2 0,0 -----------------------AACAUUCAACGCUGUCGGUGAGUau-------------------------------------------------------------- 4 0,0 -----------------------AACAUUCAACGCUGUCGGUGAGUg--------------------------------------------------------------- 4 0,0 -----------------------AACAUUCAACGCUGUCGGUGAGUU--------------------------------------------------------------- 1063 0,1 -----------------------AACAUUCAACGCUGUCGGUGAGUUa-------------------------------------------------------------- 2 0,1 -----------------------AACAUUCAACGCUGUCGGUGAGUUU-------------------------------------------------------------- 918 0,2 ------------------------ACAUUCAACGCUGUCGGUGA------------------------------------------------------------------ 31 1,-2 ------------------------ACAUUCAACGCUGUCGGUGAa----------------------------------------------------------------- 2 1,-2 ------------------------ACAUUCAACGCUGUCGGUGAaa---------------------------------------------------------------- 2 1,-2 ------------------------ACAUUCAACGCUGUCGGUGAG----------------------------------------------------------------- 29 1,-1 ------------------------ACAUUCAACGCUGUCGGUGAGa---------------------------------------------------------------- 8 1,-1 ------------------------ACAUUCAACGCUGUCGGUGAGU---------------------------------------------------------------- 123 1,0 ------------------------ACAUUCAACGCUGUCGGUGAGUU--------------------------------------------------------------- 16 1,1 ------------------------ACAUUCAACGCUGUCGGUGAGUUU-------------------------------------------------------------- 15 1,2 -------------------------CAUUCAACGCUGUCGGUGAGU---------------------------------------------------------------- 6 2,0 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGU---------------------------- 8 0,-3 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUA--------------------------- 10 0,-2 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUAC-------------------------- 15 0,-1 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUACC------------------------- 82 0,0 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUACCa------------------------ 2 0,0 >hsa-mir-181a-2 MA:39-61;mi:77-98 Normal agaagggcuaucaggccagccuucagaggacuccaaggAACAUUCAACGCUGUCGGUGAGUuugggauuugaaaaaACCACUGACCGUUGACUGUACCuugggguccuua --------------------------------------AACAUUCAACGCUGUCGG------------------------------------------------------ 143 0,-5 --------------------------------------AACAUUCAACGCUGUCGGa----------------------------------------------------- 8 0,-5 --------------------------------------AACAUUCAACGCUGUCGGc----------------------------------------------------- 2 0,-5 --------------------------------------AACAUUCAACGCUGUCGGU----------------------------------------------------- 243 0,-4 --------------------------------------AACAUUCAACGCUGUCGGUa---------------------------------------------------- 19 0,-4 --------------------------------------AACAUUCAACGCUGUCGGUaa--------------------------------------------------- 15 0,-4 --------------------------------------AACAUUCAACGCUGUCGGUau--------------------------------------------------- 2 0,-4 --------------------------------------AACAUUCAACGCUGUCGGUu---------------------------------------------------- 12 0,-4 --------------------------------------AACAUUCAACGCUGUCGGUG---------------------------------------------------- 359 0,-3 --------------------------------------AACAUUCAACGCUGUCGGUGc--------------------------------------------------- 4 0,-3 --------------------------------------AACAUUCAACGCUGUCGGUGu--------------------------------------------------- 124 0,-3 --------------------------------------AACAUUCAACGCUGUCGGUGuu-------------------------------------------------- 5 0,-3 --------------------------------------AACAUUCAACGCUGUCGGUGA--------------------------------------------------- 1304 0,-2 --------------------------------------AACAUUCAACGCUGUCGGUGAa-------------------------------------------------- 262 0,-2 --------------------------------------AACAUUCAACGCUGUCGGUGAaa------------------------------------------------- 53 0,-2 --------------------------------------AACAUUCAACGCUGUCGGUGAau------------------------------------------------- 31 0,-2 --------------------------------------AACAUUCAACGCUGUCGGUGAc-------------------------------------------------- 2 0,-2 --------------------------------------AACAUUCAACGCUGUCGGUGAu-------------------------------------------------- 34 0,-2 --------------------------------------AACAUUCAACGCUGUCGGUGAuu------------------------------------------------- 14 0,-2 --------------------------------------AACAUUCAACGCUGUCGGUGAG-------------------------------------------------- 1377 0,-1 --------------------------------------AACAUUCAACGCUGUCGGUGAGa------------------------------------------------- 921 0,-1 --------------------------------------AACAUUCAACGCUGUCGGUGAGaa------------------------------------------------ 19 0,-1 --------------------------------------AACAUUCAACGCUGUCGGUGAGau------------------------------------------------ 7 0,-1 --------------------------------------AACAUUCAACGCUGUCGGUGAGc------------------------------------------------- 34 0,-1 --------------------------------------AACAUUCAACGCUGUCGGUGAGg------------------------------------------------- 21 0,-1 --------------------------------------AACAUUCAACGCUGUCGGUGAGU------------------------------------------------- 6649 0,0 --------------------------------------AACAUUCAACGCUGUCGGUGAGUa------------------------------------------------ 15 0,0 --------------------------------------AACAUUCAACGCUGUCGGUGAGUaa----------------------------------------------- 2 0,0 --------------------------------------AACAUUCAACGCUGUCGGUGAGUau----------------------------------------------- 4 0,0 --------------------------------------AACAUUCAACGCUGUCGGUGAGUg------------------------------------------------ 4 0,0 --------------------------------------AACAUUCAACGCUGUCGGUGAGUU------------------------------------------------ 1063 0,1 --------------------------------------AACAUUCAACGCUGUCGGUGAGUUa----------------------------------------------- 2 0,1 --------------------------------------AACAUUCAACGCUGUCGGUGAGUUU----------------------------------------------- 918 0,2 ---------------------------------------ACAUUCAACGCUGUCGGUGA--------------------------------------------------- 31 1,-2 ---------------------------------------ACAUUCAACGCUGUCGGUGAa-------------------------------------------------- 2 1,-2 ---------------------------------------ACAUUCAACGCUGUCGGUGAaa------------------------------------------------- 2 1,-2 ---------------------------------------ACAUUCAACGCUGUCGGUGAG-------------------------------------------------- 29 1,-1 ---------------------------------------ACAUUCAACGCUGUCGGUGAGa------------------------------------------------- 8 1,-1 ---------------------------------------ACAUUCAACGCUGUCGGUGAGU------------------------------------------------- 123 1,0 ---------------------------------------ACAUUCAACGCUGUCGGUGAGUU------------------------------------------------ 16 1,1 ---------------------------------------ACAUUCAACGCUGUCGGUGAGUUU----------------------------------------------- 15 1,2 ----------------------------------------CAUUCAACGCUGUCGGUGAGU------------------------------------------------- 6 2,0 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGU--------------- 15 0,-3 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGUA-------------- 7 0,-2 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGUAC------------- 43 0,-1 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGUACa------------ 3 0,-1 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGUACC------------ 54 0,0 >hsa-mir-181b-1 5pM:36-58 Normal ccugugcagagauuauuuuuuaaaaggucacaaucAACAUUCAUUGCUGUCGGUGGGUugaacuguguggacaagcucacugaacaaugaaugcaacuguggccccgcuu -----------------------------------AACAUUCAUUGCUGUCGGU-------------------------------------------------------- 21 0,-4 -----------------------------------AACAUUCAUUGCUGUCGGUG------------------------------------------------------- 47 0,-3 -----------------------------------AACAUUCAUUGCUGUCGGUGa------------------------------------------------------ 9 0,-3 -----------------------------------AACAUUCAUUGCUGUCGGUGaa----------------------------------------------------- 4 0,-3 -----------------------------------AACAUUCAUUGCUGUCGGUGu------------------------------------------------------ 10 0,-3 -----------------------------------AACAUUCAUUGCUGUCGGUGG------------------------------------------------------ 40 0,-2 -----------------------------------AACAUUCAUUGCUGUCGGUGGa----------------------------------------------------- 40 0,-2 -----------------------------------AACAUUCAUUGCUGUCGGUGGaa---------------------------------------------------- 4 0,-2 -----------------------------------AACAUUCAUUGCUGUCGGUGGau---------------------------------------------------- 6 0,-2 -----------------------------------AACAUUCAUUGCUGUCGGUGGG----------------------------------------------------- 31 0,-1 -----------------------------------AACAUUCAUUGCUGUCGGUGGGa---------------------------------------------------- 73 0,-1 -----------------------------------AACAUUCAUUGCUGUCGGUGGGaa--------------------------------------------------- 4 0,-1 -----------------------------------AACAUUCAUUGCUGUCGGUGGGau--------------------------------------------------- 8 0,-1 -----------------------------------AACAUUCAUUGCUGUCGGUGGGc---------------------------------------------------- 2 0,-1 -----------------------------------AACAUUCAUUGCUGUCGGUGGGg---------------------------------------------------- 2 0,-1 -----------------------------------AACAUUCAUUGCUGUCGGUGGGU---------------------------------------------------- 323 0,0 -----------------------------------AACAUUCAUUGCUGUCGGUGGGUa--------------------------------------------------- 5 0,0 -----------------------------------AACAUUCAUUGCUGUCGGUGGGUaa-------------------------------------------------- 5 0,0 -----------------------------------AACAUUCAUUGCUGUCGGUGGGUau-------------------------------------------------- 2 0,0 -----------------------------------AACAUUCAUUGCUGUCGGUGGGUU--------------------------------------------------- 237 0,1 ------------------------------------ACAUUCAUUGCUGUCGGUau------------------------------------------------------ 2 1,-4 ------------------------------------ACAUUCAUUGCUGUCGGUGGGU---------------------------------------------------- 15 1,0 ------------------------------------ACAUUCAUUGCUGUCGGUGGGUU--------------------------------------------------- 12 1,1 >hsa-mir-181b-2 5pM:16-38 Normal cugauggcugcacucAACAUUCAUUGCUGUCGGUGGGUuugagucugaaucaacucacugaucaaugaaugcaaacugcggaccaaaca ---------------AACAUUCAUUGCUGUCGGU------------------------------------------------------- 21 0,-4 ---------------AACAUUCAUUGCUGUCGGUG------------------------------------------------------ 47 0,-3 ---------------AACAUUCAUUGCUGUCGGUGa----------------------------------------------------- 9 0,-3 ---------------AACAUUCAUUGCUGUCGGUGaa---------------------------------------------------- 4 0,-3 ---------------AACAUUCAUUGCUGUCGGUGu----------------------------------------------------- 10 0,-3 ---------------AACAUUCAUUGCUGUCGGUGG----------------------------------------------------- 40 0,-2 ---------------AACAUUCAUUGCUGUCGGUGGa---------------------------------------------------- 40 0,-2 ---------------AACAUUCAUUGCUGUCGGUGGaa--------------------------------------------------- 4 0,-2 ---------------AACAUUCAUUGCUGUCGGUGGau--------------------------------------------------- 6 0,-2 ---------------AACAUUCAUUGCUGUCGGUGGG---------------------------------------------------- 31 0,-1 ---------------AACAUUCAUUGCUGUCGGUGGGa--------------------------------------------------- 73 0,-1 ---------------AACAUUCAUUGCUGUCGGUGGGaa-------------------------------------------------- 4 0,-1 ---------------AACAUUCAUUGCUGUCGGUGGGau-------------------------------------------------- 8 0,-1 ---------------AACAUUCAUUGCUGUCGGUGGGc--------------------------------------------------- 2 0,-1 ---------------AACAUUCAUUGCUGUCGGUGGGg--------------------------------------------------- 2 0,-1 ---------------AACAUUCAUUGCUGUCGGUGGGU--------------------------------------------------- 323 0,0 ---------------AACAUUCAUUGCUGUCGGUGGGUa-------------------------------------------------- 5 0,0 ---------------AACAUUCAUUGCUGUCGGUGGGUaa------------------------------------------------- 5 0,0 ---------------AACAUUCAUUGCUGUCGGUGGGUau------------------------------------------------- 2 0,0 ---------------AACAUUCAUUGCUGUCGGUGGGUU-------------------------------------------------- 237 0,1 ---------------AACAUUCAUUGCUGUCGGUGGGUUU------------------------------------------------- 99 0,2 ----------------ACAUUCAUUGCUGUCGGUau----------------------------------------------------- 2 1,-4 ----------------ACAUUCAUUGCUGUCGGUGGGU--------------------------------------------------- 15 1,0 ----------------ACAUUCAUUGCUGUCGGUGGGUU-------------------------------------------------- 12 1,1 >hsa-mir-181c MA:27-48;mi:65-86 Normal cggaaaauuugccaaggguuugggggAACAUUCAACCUGUCGGUGAGUuugggcagcucaggcaAACCAUCGACCGUUGAGUGGACccugaggccuggaauugccauccu --------------------------AACAUUCAACCUGUCGGUGA---------------------------------------------------------------- 3 0,-2 --------------------------AACAUUCAACCUGUCGGUGAG--------------------------------------------------------------- 10 0,-1 --------------------------AACAUUCAACCUGUCGGUGAGa-------------------------------------------------------------- 15 0,-1 --------------------------AACAUUCAACCUGUCGGUGAGU-------------------------------------------------------------- 154 0,0 --------------------------AACAUUCAACCUGUCGGUGAGUU------------------------------------------------------------- 116 0,1 --------------------------AACAUUCAACCUGUCGGUGAGUUU------------------------------------------------------------ 95 0,2 --------------------------AACAUUCAACCUGUCGGUGAGUUUu----------------------------------------------------------- 2 0,2 ---------------------------ACAUUCAACCUGUCGGUGAG--------------------------------------------------------------- 2 1,-1 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGa-------------------------- 4 1,-3 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGA------------------------- 8 1,-1 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGAa------------------------ 8 1,-1 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGAaa----------------------- 2 1,-1 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGAC------------------------ 51 1,0 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGACa----------------------- 16 1,0 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGACu----------------------- 35 1,0 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGACC----------------------- 46 1,1 >hsa-mir-181d 5pM:36-58 Normal guccccuccccuaggccacagccgaggucacaaucAACAUUCAUUGUUGUCGGUGGGUugugaggacugaggccagacccaccgggggaugaaugucacuguggcugggccagacacggcuuaaggggaauggggac -----------------------------------AACAUUCAUUGUUGUCGGUG---------------------------------------------------------------------------------- 2 0,-3 -----------------------------------AACAUUCAUUGUUGUCGGUGG--------------------------------------------------------------------------------- 11 0,-2 -----------------------------------AACAUUCAUUGUUGUCGGUGGG-------------------------------------------------------------------------------- 2 0,-1 -----------------------------------AACAUUCAUUGUUGUCGGUGGGa------------------------------------------------------------------------------- 7 0,-1 -----------------------------------AACAUUCAUUGUUGUCGGUGGGU------------------------------------------------------------------------------- 86 0,0 -----------------------------------AACAUUCAUUGUUGUCGGUGGGUa------------------------------------------------------------------------------ 2 0,0 -----------------------------------AACAUUCAUUGUUGUCGGUGGGUau----------------------------------------------------------------------------- 2 0,0 -----------------------------------AACAUUCAUUGUUGUCGGUGGGUU------------------------------------------------------------------------------ 49 0,1 -----------------------------------AACAUUCAUUGUUGUCGGUGGGUUu----------------------------------------------------------------------------- 9 0,1 ------------------------------------ACAUUCAUUGUUGUCGGUGGGU------------------------------------------------------------------------------- 2 1,0 >hsa-mir-182 MA:23-46;mi:67-87 Normal gagcugcuugccuccccccguuUUUGGCAAUGGUAGAACUCACACUggugagguaacaggauccggUGGUUCUAGACUUGCCAACUAuggggcgaggacucagccggcac ----------------------UUUGGCAAUGGUAGAACUC--------------------------------------------------------------------- 2 0,-5 ----------------------UUUGGCAAUGGUAGAACUCA-------------------------------------------------------------------- 113 0,-4 ----------------------UUUGGCAAUGGUAGAACUCAa------------------------------------------------------------------- 2 0,-4 ----------------------UUUGGCAAUGGUAGAACUCAC------------------------------------------------------------------- 50 0,-3 ----------------------UUUGGCAAUGGUAGAACUCACA------------------------------------------------------------------ 293 0,-2 ----------------------UUUGGCAAUGGUAGAACUCACAa----------------------------------------------------------------- 8 0,-2 ----------------------UUUGGCAAUGGUAGAACUCACAC----------------------------------------------------------------- 57 0,-1 ----------------------UUUGGCAAUGGUAGAACUCACACU---------------------------------------------------------------- 307 0,0 ----------------------UUUGGCAAUGGUAGAACUCACACUG--------------------------------------------------------------- 41 0,1 -----------------------UUGGCAAUGGUAGAACUCACA------------------------------------------------------------------ 2 1,-2 -----------------------UUGGCAAUGGUAGAACUCACAC----------------------------------------------------------------- 2 1,-1 -----------------------UUGGCAAUGGUAGAACUCACACU---------------------------------------------------------------- 4 1,0 ----------------------------------------------------------------GGUGGUUCUAGACUUGCCAACU------------------------ 11 -2,-1 ------------------------------------------------------------------UGGUUCUAGACUUGCCAACU------------------------ 4 0,-1 >hsa-mir-183 MA:27-48;mi:66-87 Normal ccgcagagugugacuccuguucugugUAUGGCACUGGUAGAAUUCACUgugaacagucucagucaGUGAAUUACCGAAGGGCCAUAAacagagcagagacagauccacga --------------------------UAUGGCACUGGUAGAAUUCA---------------------------------------------------------------- 13 0,-2 --------------------------UAUGGCACUGGUAGAAUUCACU-------------------------------------------------------------- 93 0,0 --------------------------UAUGGCACUGGUAGAAUUCACUG------------------------------------------------------------- 25 0,1 --------------------------UAUGGCACUGGUAGAAUUCACUGU------------------------------------------------------------ 3 0,2 ---------------------------AUGGCACUGGUAGAAUUCA---------------------------------------------------------------- 3 1,-2 ---------------------------AUGGCACUGGUAGAAUUCAC--------------------------------------------------------------- 2 1,-1 ---------------------------AUGGCACUGGUAGAAUUCACU-------------------------------------------------------------- 100 1,0 ---------------------------AUGGCACUGGUAGAAUUCACUG------------------------------------------------------------- 53 1,1 ---------------------------AUGGCACUGGUAGAAUUCACUGa------------------------------------------------------------ 15 1,1 ---------------------------AUGGCACUGGUAGAAUUCACUGU------------------------------------------------------------ 22 1,2 >hsa-mir-184 3pM:53-74 Normal ccagucacguccccuuaucacuuuuccagcccagcuuugugacuguaaguguUGGACGGAGAACUGAUAAGGGUaggugauuga ----------------------------------------------------UGGACGGAGAACUGAUAAGGGU---------- 2 0,0 >hsa-mir-185 MA:15-36;mi:50-71 Normal agggggcgagggauUGGAGAGAAAGGCAGUUCCUGAugguccccuccccAGGGGCUGGCUUUCCUCUGGUCcuucccuccca --------------UGGAGAGAAAGGCAGUUC-------------------------------------------------- 7 0,-4 --------------UGGAGAGAAAGGCAGUUCC------------------------------------------------- 9 0,-3 --------------UGGAGAGAAAGGCAGUUCCU------------------------------------------------ 102 0,-2 --------------UGGAGAGAAAGGCAGUUCCUa----------------------------------------------- 2 0,-2 --------------UGGAGAGAAAGGCAGUUCCUaa---------------------------------------------- 4 0,-2 --------------UGGAGAGAAAGGCAGUUCCUG----------------------------------------------- 365 0,-1 --------------UGGAGAGAAAGGCAGUUCCUGc---------------------------------------------- 2 0,-1 --------------UGGAGAGAAAGGCAGUUCCUGg---------------------------------------------- 2 0,-1 --------------UGGAGAGAAAGGCAGUUCCUGu---------------------------------------------- 50 0,-1 --------------UGGAGAGAAAGGCAGUUCCUGuu--------------------------------------------- 5 0,-1 --------------UGGAGAGAAAGGCAGUUCCUGA---------------------------------------------- 1895 0,0 --------------UGGAGAGAAAGGCAGUUCCUGAa--------------------------------------------- 378 0,0 --------------UGGAGAGAAAGGCAGUUCCUGAaa-------------------------------------------- 37 0,0 --------------UGGAGAGAAAGGCAGUUCCUGAau-------------------------------------------- 32 0,0 --------------UGGAGAGAAAGGCAGUUCCUGAg--------------------------------------------- 24 0,0 --------------UGGAGAGAAAGGCAGUUCCUGAU--------------------------------------------- 174 0,1 --------------UGGAGAGAAAGGCAGUUCCUGAUa-------------------------------------------- 4 0,1 --------------UGGAGAGAAAGGCAGUUCCUGAUu-------------------------------------------- 8 0,1 ---------------GGAGAGAAAGGCAGUUCCUG----------------------------------------------- 8 1,-1 ---------------GGAGAGAAAGGCAGUUCCUGA---------------------------------------------- 68 1,0 ---------------GGAGAGAAAGGCAGUUCCUGAa--------------------------------------------- 5 1,0 ---------------GGAGAGAAAGGCAGUUCCUGAU--------------------------------------------- 2 1,1 ------------------------------------------------CAGGGGCUGGCUUUCCUCUGGU------------ 8 -1,-1 -------------------------------------------------AGGGGCUGGCUUUCCUCUGG------------- 3 0,-2 -------------------------------------------------AGGGGCUGGCUUUCCUCUGGU------------ 54 0,-1 -------------------------------------------------AGGGGCUGGCUUUCCUCUGGUu----------- 9 0,-1 --------------------------------------------------GGGGCUGGCUUUCCUCUGGU------------ 2 1,-1 >hsa-mir-186 MA:15-36;mi:54-75 Normal ugcuuguaacuuucCAAAGAAUUCUCCUUUUGGGCUuucugguuuuauuuuaaGCCCAAAGGUGAAUUUUUUGGGaaguuugagcu -------------CCAAAGAAUUCUCCUUUUGGG---------------------------------------------------- 2 -1,-2 -------------CCAAAGAAUUCUCCUUUUGGGC--------------------------------------------------- 10 -1,-1 -------------CCAAAGAAUUCUCCUUUUGGGCU-------------------------------------------------- 26 -1,0 --------------CAAAGAAUUCUCCUUUUG------------------------------------------------------ 98 0,-4 --------------CAAAGAAUUCUCCUUUUGa----------------------------------------------------- 2 0,-4 --------------CAAAGAAUUCUCCUUUUGG----------------------------------------------------- 87 0,-3 --------------CAAAGAAUUCUCCUUUUGGa---------------------------------------------------- 11 0,-3 --------------CAAAGAAUUCUCCUUUUGGG---------------------------------------------------- 202 0,-2 --------------CAAAGAAUUCUCCUUUUGGGa--------------------------------------------------- 75 0,-2 --------------CAAAGAAUUCUCCUUUUGGGaa-------------------------------------------------- 89 0,-2 --------------CAAAGAAUUCUCCUUUUGGGuu-------------------------------------------------- 2 0,-2 --------------CAAAGAAUUCUCCUUUUGGGC--------------------------------------------------- 283 0,-1 --------------CAAAGAAUUCUCCUUUUGGGCa-------------------------------------------------- 120 0,-1 --------------CAAAGAAUUCUCCUUUUGGGCaa------------------------------------------------- 39 0,-1 --------------CAAAGAAUUCUCCUUUUGGGCau------------------------------------------------- 27 0,-1 --------------CAAAGAAUUCUCCUUUUGGGCU-------------------------------------------------- 2062 0,0 --------------CAAAGAAUUCUCCUUUUGGGCUa------------------------------------------------- 39 0,0 --------------CAAAGAAUUCUCCUUUUGGGCUaa------------------------------------------------ 2 0,0 --------------CAAAGAAUUCUCCUUUUGGGCUau------------------------------------------------ 2 0,0 --------------CAAAGAAUUCUCCUUUUGGGCUc------------------------------------------------- 3 0,0 --------------CAAAGAAUUCUCCUUUUGGGCUU------------------------------------------------- 1514 0,1 --------------CAAAGAAUUCUCCUUUUGGGCUUa------------------------------------------------ 10 0,1 --------------CAAAGAAUUCUCCUUUUGGGCUUau----------------------------------------------- 2 0,1 --------------CAAAGAAUUCUCCUUUUGGGCUUg------------------------------------------------ 2 0,1 --------------CAAAGAAUUCUCCUUUUGGGCUUU------------------------------------------------ 212 0,2 --------------CAAAGAAUUCUCCUUUUGGGCUUUu----------------------------------------------- 18 0,2 ---------------AAAGAAUUCUCCUUUUGGG---------------------------------------------------- 3 1,-2 ---------------AAAGAAUUCUCCUUUUGGGa--------------------------------------------------- 2 1,-2 ---------------AAAGAAUUCUCCUUUUGGGaa-------------------------------------------------- 4 1,-2 ---------------AAAGAAUUCUCCUUUUGGGC--------------------------------------------------- 6 1,-1 ---------------AAAGAAUUCUCCUUUUGGGCa-------------------------------------------------- 5 1,-1 ---------------AAAGAAUUCUCCUUUUGGGCU-------------------------------------------------- 109 1,0 ---------------AAAGAAUUCUCCUUUUGGGCUa------------------------------------------------- 3 1,0 ---------------AAAGAAUUCUCCUUUUGGGCUU------------------------------------------------- 145 1,1 ---------------AAAGAAUUCUCCUUUUGGGCUUU------------------------------------------------ 23 1,2 ---------------AAAGAAUUCUCCUUUUGGGCUUUu----------------------------------------------- 2 1,2 -----------------------------------------------------GCCCAAAGGUGAAUUUUUUGG------------ 4 0,-1 -----------------------------------------------------GCCCAAAGGUGAAUUUUUUGGa----------- 4 0,-1 -----------------------------------------------------GCCCAAAGGUGAAUUUUUUGGGA---------- 7 0,1 ------------------------------------------------------CCCAAAGGUGAAUUUUUUGGGA---------- 17 1,1 >hsa-mir-187 mi:35-56;MA:71-92 Normal ggucgggcucaccaugacacagugugagaccucgGGCUACAACACAGGACCCGGGCgcugcucugaccccUCGUGUCUUGUGUUGCAGCCGGagggacgcagguccgca ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCG------------------ 2 0,-1 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCGGu---------------- 2 0,0 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCGGuu--------------- 3 0,0 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCGGA---------------- 4 0,1 -----------------------------------------------------------------------CGUGUCUUGUGUUGCAGCCGGuu--------------- 3 1,0 >hsa-mir-188 5p:15-35;3p:54-74 Normal ugcucccucucucaCAUCCCUUGCAUGGUGGAGGGugagcuuucugaaaacccCUCCCACAUGCAGGGUUUGCAggauggcgagcc --------------CAUCCCUUGCAUGGUGGAG----------------------------------------------------- 2 0,-2 --------------CAUCCCUUGCAUGGUGGAGG---------------------------------------------------- 2 0,-1 --------------CAUCCCUUGCAUGGUGGAGGG--------------------------------------------------- 3 0,0 --------------CAUCCCUUGCAUGGUGGAGGGa-------------------------------------------------- 5 0,0 --------------CAUCCCUUGCAUGGUGGAGGGU-------------------------------------------------- 18 0,1 --------------CAUCCCUUGCAUGGUGGAGGGUa------------------------------------------------- 5 0,1 --------------CAUCCCUUGCAUGGUGGAGGGUu------------------------------------------------- 4 0,1 ---------------AUCCCUUGCAUGGUGGAGGGU-------------------------------------------------- 2 1,1 -----------------------------------------------------CUCCCACAUGCAGGGUUUGCA------------ 4 0,0 >hsa-mir-18a MA:6-28;mi:47-69 Normal uguucUAAGGUGCAUCUAGUGCAGAUAGugaaguagauuagcaucuACUGCCCUAAGUGCUCCUUCUGGca -----UAAGGUGCAUCUAGUGCAG----------------------------------------------- 2 0,-4 -----UAAGGUGCAUCUAGUGCAGA---------------------------------------------- 55 0,-3 -----UAAGGUGCAUCUAGUGCAGAa--------------------------------------------- 3 0,-3 -----UAAGGUGCAUCUAGUGCAGAaa-------------------------------------------- 6 0,-3 -----UAAGGUGCAUCUAGUGCAGAU--------------------------------------------- 100 0,-2 -----UAAGGUGCAUCUAGUGCAGAUA-------------------------------------------- 87 0,-1 -----UAAGGUGCAUCUAGUGCAGAUAa------------------------------------------- 2 0,-1 -----UAAGGUGCAUCUAGUGCAGAUAG------------------------------------------- 83 0,0 -----UAAGGUGCAUCUAGUGCAGAUAGa------------------------------------------ 3 0,0 -----UAAGGUGCAUCUAGUGCAGAUAGU------------------------------------------ 2 0,1 ------AAGGUGCAUCUAGUGCAGA---------------------------------------------- 2 1,-3 ------AAGGUGCAUCUAGUGCAGAU--------------------------------------------- 2 1,-2 ------AAGGUGCAUCUAGUGCAGAUA-------------------------------------------- 3 1,-1 ------AAGGUGCAUCUAGUGCAGAUAG------------------------------------------- 4 1,0 ----------------------------------------------ACUGCCCUAAGUGCUCCUUC----- 2 0,-3 ----------------------------------------------ACUGCCCUAAGUGCUCCUUCUGG-- 8 0,0 >hsa-mir-18b MA:6-28;mi:49-70 Normal uguguUAAGGUGCAUCUAGUGCAGUUAGugaagcagcuuagaaucuacUGCCCUAAAUGCCCCUUCUGGCa -----UAAGGUGCAUCUAGUGCAG----------------------------------------------- 2 0,-4 -----UAAGGUGCAUCUAGUGCAGUU--------------------------------------------- 4 0,-2 >hsa-mir-190 5pM:15-36 Normal ugcaggccucugugUGAUAUGUUUGAUAUAUUAGGUuguuauuuaauccaacuauauaucaaacauauuccuacagugucuugcc --------------UGAUAUGUUUGAUAUAUUA---------------------------------------------------- 8 0,-3 --------------UGAUAUGUUUGAUAUAUUAG--------------------------------------------------- 5 0,-2 --------------UGAUAUGUUUGAUAUAUUAGa-------------------------------------------------- 2 0,-2 --------------UGAUAUGUUUGAUAUAUUAGu-------------------------------------------------- 10 0,-2 --------------UGAUAUGUUUGAUAUAUUAGuu------------------------------------------------- 7 0,-2 --------------UGAUAUGUUUGAUAUAUUAGG-------------------------------------------------- 84 0,-1 --------------UGAUAUGUUUGAUAUAUUAGGa------------------------------------------------- 33 0,-1 --------------UGAUAUGUUUGAUAUAUUAGGU------------------------------------------------- 181 0,0 --------------UGAUAUGUUUGAUAUAUUAGGUa------------------------------------------------ 11 0,0 --------------UGAUAUGUUUGAUAUAUUAGGUg------------------------------------------------ 2 0,0 --------------UGAUAUGUUUGAUAUAUUAGGUU------------------------------------------------ 236 0,1 --------------UGAUAUGUUUGAUAUAUUAGGUUa----------------------------------------------- 3 0,1 --------------UGAUAUGUUUGAUAUAUUAGGUUu----------------------------------------------- 2 0,1 --------------UGAUAUGUUUGAUAUAUUAGGUUG----------------------------------------------- 26 0,2 --------------UGAUAUGUUUGAUAUAUUAGGUUGU---------------------------------------------- 2 0,3 ---------------GAUAUGUUUGAUAUAUUAGGU------------------------------------------------- 2 1,0 ---------------GAUAUGUUUGAUAUAUUAGGUU------------------------------------------------ 5 1,1 --------------------------------------------------ACUAUAUAUCAAACAUAUUCCU------------- 9 >hsa-mir-190b 5pM:11-31 Normal ugcuucugugUGAUAUGUUUGAUAUUGGGUUguuuaauuaggaaccaacuaaaugucaaacauauucuuacagcagcag ----------UGAUAUGUUUGAUAUUGGGUUa----------------------------------------------- 2 0,0 ----------UGAUAUGUUUGAUAUUGGGUUG----------------------------------------------- 53 0,1 ----------UGAUAUGUUUGAUAUUGGGUUGa---------------------------------------------- 9 0,1 ----------UGAUAUGUUUGAUAUUGGGUUGU---------------------------------------------- 13 0,2 >hsa-mir-191 MA:16-38;mi:58-79 Normal cggcuggacagcgggCAACGGAAUCCCAAAAGCAGCUGuugucuccagagcauuccaGCUGCGCUUGGAUUUCGUCCCCugcucuccugccu ---------------CAACGGAAUCCCAAAAGC----------------------------------------------------------- 49 0,-5 ---------------CAACGGAAUCCCAAAAGCA---------------------------------------------------------- 179 0,-4 ---------------CAACGGAAUCCCAAAAGCAa--------------------------------------------------------- 67 0,-4 ---------------CAACGGAAUCCCAAAAGCAG--------------------------------------------------------- 829 0,-3 ---------------CAACGGAAUCCCAAAAGCAGa-------------------------------------------------------- 19 0,-3 ---------------CAACGGAAUCCCAAAAGCAGaa------------------------------------------------------- 2 0,-3 ---------------CAACGGAAUCCCAAAAGCAGau------------------------------------------------------- 6 0,-3 ---------------CAACGGAAUCCCAAAAGCAGu-------------------------------------------------------- 2 0,-3 ---------------CAACGGAAUCCCAAAAGCAGuu------------------------------------------------------- 8 0,-3 ---------------CAACGGAAUCCCAAAAGCAGC-------------------------------------------------------- 959 0,-2 ---------------CAACGGAAUCCCAAAAGCAGCa------------------------------------------------------- 130 0,-2 ---------------CAACGGAAUCCCAAAAGCAGCaa------------------------------------------------------ 5 0,-2 ---------------CAACGGAAUCCCAAAAGCAGCau------------------------------------------------------ 5 0,-2 ---------------CAACGGAAUCCCAAAAGCAGCc------------------------------------------------------- 6 0,-2 ---------------CAACGGAAUCCCAAAAGCAGCg------------------------------------------------------- 7 0,-2 ---------------CAACGGAAUCCCAAAAGCAGCU------------------------------------------------------- 5932 0,-1 ---------------CAACGGAAUCCCAAAAGCAGCUa------------------------------------------------------ 108 0,-1 ---------------CAACGGAAUCCCAAAAGCAGCUau----------------------------------------------------- 6 0,-1 ---------------CAACGGAAUCCCAAAAGCAGCUc------------------------------------------------------ 6 0,-1 ---------------CAACGGAAUCCCAAAAGCAGCUu------------------------------------------------------ 203 0,-1 ---------------CAACGGAAUCCCAAAAGCAGCUuu----------------------------------------------------- 10 0,-1 ---------------CAACGGAAUCCCAAAAGCAGCUG------------------------------------------------------ 2813 0,0 ---------------CAACGGAAUCCCAAAAGCAGCUGa----------------------------------------------------- 71 0,0 ---------------CAACGGAAUCCCAAAAGCAGCUGaa---------------------------------------------------- 2 0,0 ---------------CAACGGAAUCCCAAAAGCAGCUGg----------------------------------------------------- 2 0,0 ---------------CAACGGAAUCCCAAAAGCAGCUGU----------------------------------------------------- 404 0,1 ---------------CAACGGAAUCCCAAAAGCAGCUGUU---------------------------------------------------- 11 0,2 ----------------AACGGAAUCCCAAAAGCA---------------------------------------------------------- 9 1,-4 ----------------AACGGAAUCCCAAAAGCAa--------------------------------------------------------- 2 1,-4 ----------------AACGGAAUCCCAAAAGCAG--------------------------------------------------------- 43 1,-3 ----------------AACGGAAUCCCAAAAGCAGC-------------------------------------------------------- 48 1,-2 ----------------AACGGAAUCCCAAAAGCAGCa------------------------------------------------------- 4 1,-2 ----------------AACGGAAUCCCAAAAGCAGCc------------------------------------------------------- 2 1,-2 ----------------AACGGAAUCCCAAAAGCAGCU------------------------------------------------------- 318 1,-1 ----------------AACGGAAUCCCAAAAGCAGCUa------------------------------------------------------ 6 1,-1 ----------------AACGGAAUCCCAAAAGCAGCUu------------------------------------------------------ 8 1,-1 ----------------AACGGAAUCCCAAAAGCAGCUG------------------------------------------------------ 305 1,0 ----------------AACGGAAUCCCAAAAGCAGCUGa----------------------------------------------------- 20 1,0 ----------------AACGGAAUCCCAAAAGCAGCUGU----------------------------------------------------- 95 1,1 ----------------AACGGAAUCCCAAAAGCAGCUGUU---------------------------------------------------- 2 1,2 -----------------ACGGAAUCCCAAAAGCAGCU------------------------------------------------------- 3 2,-1 -----------------ACGGAAUCCCAAAAGCAGCUG------------------------------------------------------ 3 2,0 ---------------------------------------------------------GCUGCGCUUGGAUUUCGUCCCC------------- 2 0,0 >hsa-mir-192 MA:24-44;mi:67-88 Normal gccgagaccgagugcacagggcuCUGACCUAUGAAUUGACAGCCagugcucucgucuccccucuggCUGCCAAUUCCAUAGGUCACAGguauguucgccucaaugccagc -----------------------CUGACCUAUGAAUUGACAG-------------------------------------------------------------------- 5 0,-2 -----------------------CUGACCUAUGAAUUGACAGC------------------------------------------------------------------- 44 0,-1 -----------------------CUGACCUAUGAAUUGACAGCa------------------------------------------------------------------ 4 0,-1 -----------------------CUGACCUAUGAAUUGACAGCC------------------------------------------------------------------ 193 0,0 -----------------------CUGACCUAUGAAUUGACAGCCg----------------------------------------------------------------- 2 0,0 -----------------------CUGACCUAUGAAUUGACAGCCu----------------------------------------------------------------- 6 0,0 -----------------------CUGACCUAUGAAUUGACAGCCuu---------------------------------------------------------------- 2 0,0 -----------------------CUGACCUAUGAAUUGACAGCCA----------------------------------------------------------------- 74 0,1 -----------------------CUGACCUAUGAAUUGACAGCCAa---------------------------------------------------------------- 3 0,1 -----------------------CUGACCUAUGAAUUGACAGCCAu---------------------------------------------------------------- 21 0,1 -----------------------CUGACCUAUGAAUUGACAGCCAuu--------------------------------------------------------------- 2 0,1 ------------------------UGACCUAUGAAUUGACAGC------------------------------------------------------------------- 5 1,-1 ------------------------UGACCUAUGAAUUGACAGCC------------------------------------------------------------------ 19 1,0 ------------------------UGACCUAUGAAUUGACAGCCA----------------------------------------------------------------- 33 1,1 ------------------------UGACCUAUGAAUUGACAGCCAa---------------------------------------------------------------- 4 1,1 ------------------------UGACCUAUGAAUUGACAGCCAau--------------------------------------------------------------- 2 1,1 ------------------------UGACCUAUGAAUUGACAGCCAu---------------------------------------------------------------- 2 1,1 ------------------------UGACCUAUGAAUUGACAGCCAG---------------------------------------------------------------- 5 1,2 ------------------------UGACCUAUGAAUUGACAGCCAGa--------------------------------------------------------------- 12 1,2 ------------------------UGACCUAUGAAUUGACAGCCAGU--------------------------------------------------------------- 44 1,3 >hsa-mir-193a 5p:21-42;3p:55-76 Normal cgaggaugggagcugagggcUGGGUCUUUGCGGGCGAGAUGAgggugucggaucAACUGGCCUACAAAGUCCCAGUucucggcccccg -------------------CUGGGUCUUUGCGGGCGAGAUG----------------------------------------------- 2 -1,-1 -------------------CUGGGUCUUUGCGGGCGAGAUGA---------------------------------------------- 8 -1,0 --------------------UGGGUCUUUGCGGGCGAG-------------------------------------------------- 52 0,-4 --------------------UGGGUCUUUGCGGGCGAGu------------------------------------------------- 6 0,-4 --------------------UGGGUCUUUGCGGGCGAGA------------------------------------------------- 123 0,-3 --------------------UGGGUCUUUGCGGGCGAGAa------------------------------------------------ 27 0,-3 --------------------UGGGUCUUUGCGGGCGAGAaa----------------------------------------------- 30 0,-3 --------------------UGGGUCUUUGCGGGCGAGAau----------------------------------------------- 12 0,-3 --------------------UGGGUCUUUGCGGGCGAGAU------------------------------------------------ 544 0,-2 --------------------UGGGUCUUUGCGGGCGAGAUa----------------------------------------------- 15 0,-2 --------------------UGGGUCUUUGCGGGCGAGAUaa---------------------------------------------- 16 0,-2 --------------------UGGGUCUUUGCGGGCGAGAUau---------------------------------------------- 2 0,-2 --------------------UGGGUCUUUGCGGGCGAGAUu----------------------------------------------- 88 0,-2 --------------------UGGGUCUUUGCGGGCGAGAUuu---------------------------------------------- 2 0,-2 --------------------UGGGUCUUUGCGGGCGAGAUG----------------------------------------------- 277 0,-1 --------------------UGGGUCUUUGCGGGCGAGAUGc---------------------------------------------- 8 0,-1 --------------------UGGGUCUUUGCGGGCGAGAUGg---------------------------------------------- 2 0,-1 --------------------UGGGUCUUUGCGGGCGAGAUGu---------------------------------------------- 106 0,-1 --------------------UGGGUCUUUGCGGGCGAGAUGuu--------------------------------------------- 11 0,-1 --------------------UGGGUCUUUGCGGGCGAGAUGA---------------------------------------------- 3102 0,0 --------------------UGGGUCUUUGCGGGCGAGAUGAa--------------------------------------------- 279 0,0 --------------------UGGGUCUUUGCGGGCGAGAUGAaa-------------------------------------------- 27 0,0 --------------------UGGGUCUUUGCGGGCGAGAUGAau-------------------------------------------- 15 0,0 --------------------UGGGUCUUUGCGGGCGAGAUGAc--------------------------------------------- 2 0,0 --------------------UGGGUCUUUGCGGGCGAGAUGAu--------------------------------------------- 187 0,0 --------------------UGGGUCUUUGCGGGCGAGAUGAuu-------------------------------------------- 3 0,0 --------------------UGGGUCUUUGCGGGCGAGAUGAG--------------------------------------------- 9 0,1 ---------------------GGGUCUUUGCGGGCGAGA------------------------------------------------- 2 1,-3 ---------------------GGGUCUUUGCGGGCGAGAU------------------------------------------------ 17 1,-2 ---------------------GGGUCUUUGCGGGCGAGAUu----------------------------------------------- 2 1,-2 ---------------------GGGUCUUUGCGGGCGAGAUG----------------------------------------------- 10 1,-1 ---------------------GGGUCUUUGCGGGCGAGAUGu---------------------------------------------- 3 1,-1 ---------------------GGGUCUUUGCGGGCGAGAUGA---------------------------------------------- 115 1,0 ---------------------GGGUCUUUGCGGGCGAGAUGAa--------------------------------------------- 4 1,0 ---------------------GGGUCUUUGCGGGCGAGAUGAu--------------------------------------------- 5 1,0 ----------------------GGUCUUUGCGGGCGAGAUGA---------------------------------------------- 2 2,0 ------------------------------------------------------AACUGGCCUACAAAGUCC---------------- 51 0,-4 ------------------------------------------------------AACUGGCCUACAAAGUCCC--------------- 56 0,-3 ------------------------------------------------------AACUGGCCUACAAAGUCCCc-------------- 3 0,-3 ------------------------------------------------------AACUGGCCUACAAAGUCCCA-------------- 224 0,-2 ------------------------------------------------------AACUGGCCUACAAAGUCCCAa------------- 48 0,-2 ------------------------------------------------------AACUGGCCUACAAAGUCCCAaa------------ 15 0,-2 ------------------------------------------------------AACUGGCCUACAAAGUCCCAau------------ 30 0,-2 ------------------------------------------------------AACUGGCCUACAAAGUCCCAu------------- 51 0,-2 ------------------------------------------------------AACUGGCCUACAAAGUCCCAuu------------ 14 0,-2 ------------------------------------------------------AACUGGCCUACAAAGUCCCAG------------- 244 0,-1 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGa------------ 209 0,-1 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGaa----------- 15 0,-1 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGau----------- 4 0,-1 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGc------------ 6 0,-1 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGg------------ 3 0,-1 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGU------------ 1935 0,0 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGUa----------- 61 0,0 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGUaa---------- 5 0,0 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGUau---------- 2 0,0 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGUg----------- 2 0,0 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGUU----------- 104 0,1 -------------------------------------------------------ACUGGCCUACAAAGUCCCA-------------- 5 1,-2 -------------------------------------------------------ACUGGCCUACAAAGUCCCAu------------- 3 1,-2 -------------------------------------------------------ACUGGCCUACAAAGUCCCAG------------- 10 1,-1 -------------------------------------------------------ACUGGCCUACAAAGUCCCAGa------------ 3 1,-1 -------------------------------------------------------ACUGGCCUACAAAGUCCCAGU------------ 36 1,0 -------------------------------------------------------ACUGGCCUACAAAGUCCCAGUa----------- 3 1,0 >hsa-mir-193b mi:14-35;MA:51-72 Normal guggucucagaauCGGGGUUUUGAGGGCGAGAUGAguuuauguuuuauccAACUGGCCCUCAAAGUCCCGCUuuuggggucau -------------CGGGGUUUUGAGGGCGAGA--------------------------------------------------- 2 0,-3 -------------CGGGGUUUUGAGGGCGAGAU-------------------------------------------------- 26 0,-2 -------------CGGGGUUUUGAGGGCGAGAUG------------------------------------------------- 13 0,-1 -------------CGGGGUUUUGAGGGCGAGAUGu------------------------------------------------ 14 0,-1 -------------CGGGGUUUUGAGGGCGAGAUGA------------------------------------------------ 210 0,0 -------------CGGGGUUUUGAGGGCGAGAUGAa----------------------------------------------- 15 0,0 -------------CGGGGUUUUGAGGGCGAGAUGAu----------------------------------------------- 7 0,0 --------------GGGGUUUUGAGGGCGAGAUGA------------------------------------------------ 7 1,0 -------------------------------------------------CAACUGGCCCUCAAAGUCCCGCU----------- 7 -1,0 --------------------------------------------------AACUGGCCCUCAAAGUCC--------------- 23 0,-4 --------------------------------------------------AACUGGCCCUCAAAGUCCC-------------- 19 0,-3 --------------------------------------------------AACUGGCCCUCAAAGUCCCG------------- 81 0,-2 --------------------------------------------------AACUGGCCCUCAAAGUCCCGa------------ 22 0,-2 --------------------------------------------------AACUGGCCCUCAAAGUCCCGaa----------- 2 0,-2 --------------------------------------------------AACUGGCCCUCAAAGUCCCGu------------ 31 0,-2 --------------------------------------------------AACUGGCCCUCAAAGUCCCGuu----------- 11 0,-2 --------------------------------------------------AACUGGCCCUCAAAGUCCCGC------------ 577 0,-1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCa----------- 128 0,-1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCaa---------- 60 0,-1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCau---------- 73 0,-1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCc----------- 67 0,-1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCg----------- 3 0,-1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCU----------- 4053 0,0 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUa---------- 115 0,0 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUaa--------- 5 0,0 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUau--------- 44 0,0 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUc---------- 4 0,0 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUg---------- 7 0,0 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUU---------- 984 0,1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUUa--------- 2 0,1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUUU--------- 177 0,2 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUUUU-------- 24 0,3 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGa------------ 2 1,-2 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGC------------ 18 1,-1 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCa----------- 2 1,-1 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCaa---------- 3 1,-1 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCau---------- 5 1,-1 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCU----------- 162 1,0 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCUa---------- 10 1,0 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCUaa--------- 8 1,0 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCUau--------- 19 1,0 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCUU---------- 88 1,1 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCUUU--------- 36 1,2 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCUUUU-------- 3 1,3 ----------------------------------------------------CUGGCCCUCAAAGUCCCGCU----------- 3 2,0 ----------------------------------------------------CUGGCCCUCAAAGUCCCGCUU---------- 2 2,1 >hsa-mir-194-1 5pM:15-36 Normal augguguuaucaagUGUAACAGCAACUCCAUGUGGAcuguguaccaauuuccaguggagaugcuguuacuuuugaugguuaccaa --------------UGUAACAGCAACUCCAUGUGG-------------------------------------------------- 29 0,-1 --------------UGUAACAGCAACUCCAUGUGGA------------------------------------------------- 137 0,0 --------------UGUAACAGCAACUCCAUGUGGAu------------------------------------------------ 2 0,0 ---------------GUAACAGCAACUCCAUGUGGA------------------------------------------------- 6 1,0 >hsa-mir-194-2 MA:15-36;mi:51-72 Normal ugguucccgcccccUGUAACAGCAACUCCAUGUGGAagugcccacugguuCCAGUGGGGCUGCUGUUAUCUGgggcgagggccag --------------UGUAACAGCAACUCCAUGUGG-------------------------------------------------- 29 0,-1 --------------UGUAACAGCAACUCCAUGUGGA------------------------------------------------- 137 0,0 --------------UGUAACAGCAACUCCAUGUGGAu------------------------------------------------ 2 0,0 --------------UGUAACAGCAACUCCAUGUGGAA------------------------------------------------ 52 0,1 --------------UGUAACAGCAACUCCAUGUGGAAa----------------------------------------------- 2 0,1 --------------UGUAACAGCAACUCCAUGUGGAAu----------------------------------------------- 4 0,1 ---------------GUAACAGCAACUCCAUGUGGA------------------------------------------------- 6 1,0 >hsa-mir-195 MA:15-35;mi:53-74 Normal agcuucccuggcucUAGCAGCACAGAAAUAUUGGCacagggaagcgagucugCCAAUAUUGGCUGUGCUGCUCCaggcaggguggug -------------CUAGCAGCACAGAAAUAUUGGC---------------------------------------------------- 2 -1,0 -------------CUAGCAGCACAGAAAUAUUGGCAu-------------------------------------------------- 2 -1,1 --------------UAGCAGCACAGAAAUAUU------------------------------------------------------- 6 0,-3 --------------UAGCAGCACAGAAAUAUUG------------------------------------------------------ 20 0,-2 --------------UAGCAGCACAGAAAUAUUGa----------------------------------------------------- 14 0,-2 --------------UAGCAGCACAGAAAUAUUGG----------------------------------------------------- 221 0,-1 --------------UAGCAGCACAGAAAUAUUGGa---------------------------------------------------- 77 0,-1 --------------UAGCAGCACAGAAAUAUUGGaa--------------------------------------------------- 31 0,-1 --------------UAGCAGCACAGAAAUAUUGGu---------------------------------------------------- 2 0,-1 --------------UAGCAGCACAGAAAUAUUGGC---------------------------------------------------- 360 0,0 --------------UAGCAGCACAGAAAUAUUGGCg--------------------------------------------------- 8 0,0 --------------UAGCAGCACAGAAAUAUUGGCu--------------------------------------------------- 4 0,0 --------------UAGCAGCACAGAAAUAUUGGCA--------------------------------------------------- 815 0,1 --------------UAGCAGCACAGAAAUAUUGGCAa-------------------------------------------------- 242 0,1 --------------UAGCAGCACAGAAAUAUUGGCAaa------------------------------------------------- 2 0,1 --------------UAGCAGCACAGAAAUAUUGGCAau------------------------------------------------- 4 0,1 --------------UAGCAGCACAGAAAUAUUGGCAg-------------------------------------------------- 10 0,1 --------------UAGCAGCACAGAAAUAUUGGCAu-------------------------------------------------- 79 0,1 --------------UAGCAGCACAGAAAUAUUGGCAuu------------------------------------------------- 2 0,1 --------------UAGCAGCACAGAAAUAUUGGCAC-------------------------------------------------- 2 0,2 ---------------AGCAGCACAGAAAUAUUG------------------------------------------------------ 2 1,-2 ---------------AGCAGCACAGAAAUAUUGG----------------------------------------------------- 2 1,-1 ---------------AGCAGCACAGAAAUAUUGGC---------------------------------------------------- 11 1,0 ---------------AGCAGCACAGAAAUAUUGGCA--------------------------------------------------- 26 1,1 ---------------AGCAGCACAGAAAUAUUGGCAa-------------------------------------------------- 13 1,1 ---------------AGCAGCACAGAAAUAUUGGCAu-------------------------------------------------- 3 1,1 ----------------------------------------------------CCAAUAUUGGCUGUGCUGCU--------------- 5 0,-2 ----------------------------------------------------CCAAUAUUGGCUGUGCUGCUC-------------- 2 0,-1 ----------------------------------------------------CCAAUAUUGGCUGUGCUGCUCC------------- 2 0,0 ----------------------------------------------------CCAAUAUUGGCUGUGCUGCUCCc------------ 2 0,0 >hsa-mir-196a-1 5pM:7-28 Normal gugaauUAGGUAGUUUCAUGUUGUUGGGccuggguuucugaacacaacaacauuaaaccacccgauucac ------UAGGUAGUUUCAUGUUGUU--------------------------------------------- 3 0,-3 ------UAGGUAGUUUCAUGUUGUUG-------------------------------------------- 2 0,-2 ------UAGGUAGUUUCAUGUUGUUGa------------------------------------------- 2 0,-2 ------UAGGUAGUUUCAUGUUGUUGG------------------------------------------- 46 0,-1 ------UAGGUAGUUUCAUGUUGUUGGa------------------------------------------ 38 0,-1 ------UAGGUAGUUUCAUGUUGUUGGaa----------------------------------------- 4 0,-1 ------UAGGUAGUUUCAUGUUGUUGGu------------------------------------------ 2 0,-1 ------UAGGUAGUUUCAUGUUGUUGGG------------------------------------------ 78 0,0 ------UAGGUAGUUUCAUGUUGUUGGGu----------------------------------------- 26 0,0 -------AGGUAGUUUCAUGUUGUUGGG------------------------------------------ 7 1,0 >hsa-mir-196a-2 MA:25-46;mi:62-83 Normal ugcucgcucagcugaucuguggcuUAGGUAGUUUCAUGUUGUUGGGauugaguuuugaacuCGGCAACAAGAAACUGCCUGAGuuacaucagucgguuuucgucgagggc ------------------------UAGGUAGUUUCAUGUUGUU------------------------------------------------------------------- 3 0,-3 ------------------------UAGGUAGUUUCAUGUUGUUG------------------------------------------------------------------ 2 0,-2 ------------------------UAGGUAGUUUCAUGUUGUUGa----------------------------------------------------------------- 2 0,-2 ------------------------UAGGUAGUUUCAUGUUGUUGG----------------------------------------------------------------- 46 0,-1 ------------------------UAGGUAGUUUCAUGUUGUUGGa---------------------------------------------------------------- 38 0,-1 ------------------------UAGGUAGUUUCAUGUUGUUGGaa--------------------------------------------------------------- 4 0,-1 ------------------------UAGGUAGUUUCAUGUUGUUGGu---------------------------------------------------------------- 2 0,-1 ------------------------UAGGUAGUUUCAUGUUGUUGGG---------------------------------------------------------------- 78 0,0 ------------------------UAGGUAGUUUCAUGUUGUUGGGu--------------------------------------------------------------- 26 0,0 ------------------------UAGGUAGUUUCAUGUUGUUGGGA--------------------------------------------------------------- 70 0,1 ------------------------UAGGUAGUUUCAUGUUGUUGGGAa-------------------------------------------------------------- 2 0,1 -------------------------AGGUAGUUUCAUGUUGUUGGG---------------------------------------------------------------- 7 1,0 ------------------------------------------------------------UCGGCAACAAGAAACUGCCUGA---------------------------- 20 -1,-1 ------------------------------------------------------------UCGGCAACAAGAAACUGCCUGAG--------------------------- 6 -1,0 ------------------------------------------------------------UCGGCAACAAGAAACUGCCUGAGU-------------------------- 8 -1,1 >hsa-mir-196b MA:15-36;mi:50-71 Normal acuggucggugauuUAGGUAGUUUCCUGUUGUUGGGauccaccuuucucUCGACAGCACGACACUGCCUUCauuacuucaguug --------------UAGGUAGUUUCCUGUUGUU--------------------------------------------------- 2 0,-3 --------------UAGGUAGUUUCCUGUUGUUGG------------------------------------------------- 27 0,-1 --------------UAGGUAGUUUCCUGUUGUUGGa------------------------------------------------ 24 0,-1 --------------UAGGUAGUUUCCUGUUGUUGGaa----------------------------------------------- 2 0,-1 --------------UAGGUAGUUUCCUGUUGUUGGG------------------------------------------------ 44 0,0 --------------UAGGUAGUUUCCUGUUGUUGGGu----------------------------------------------- 13 0,0 --------------UAGGUAGUUUCCUGUUGUUGGGA----------------------------------------------- 44 0,1 --------------UAGGUAGUUUCCUGUUGUUGGGAU---------------------------------------------- 2 0,2 ---------------AGGUAGUUUCCUGUUGUUGGG------------------------------------------------ 2 1,0 -------------------------------------------------UCGACAGCACGACACUGCCUUCA------------ 4 0,1 --------------------------------------------------CGACAGCACGACACUGCCUUC------------- 2 1,0 >hsa-mir-197 3pM:48-69 Normal ggcugugccggguagagagggcagugggagguaagagcucuucacccUUCACCACCUUCUCCACCCAGCauggcc ----------------------------------------------CUUCACCACCUUCUCCACCCAGC------ 3 -1,0 -----------------------------------------------UUCACCACCUUCUCCACCC--------- 14 0,-3 -----------------------------------------------UUCACCACCUUCUCCACCCAa------- 2 0,-2 -----------------------------------------------UUCACCACCUUCUCCACCCAG------- 25 0,-1 -----------------------------------------------UUCACCACCUUCUCCACCCAGa------ 38 0,-1 -----------------------------------------------UUCACCACCUUCUCCACCCAGaa----- 2 0,-1 -----------------------------------------------UUCACCACCUUCUCCACCCAGu------ 14 0,-1 -----------------------------------------------UUCACCACCUUCUCCACCCAGC------ 407 0,0 -----------------------------------------------UUCACCACCUUCUCCACCCAGCu----- 6 0,0 -----------------------------------------------UUCACCACCUUCUCCACCCAGCA----- 18 0,1 ------------------------------------------------UCACCACCUUCUCCACCCAGC------ 6 1,0 >hsa-mir-199a-1 5p:6-28;3p:47-68 Normal gccaaCCCAGUGUUCAGACUACCUGUUCaggaggcucucaauguguACAGUAGUCUGCACAUUGGUUAggc ----ACCCAGUGUUCAGACUACCUGUU-------------------------------------------- 2 -1,-1 -----CCCAGUGUUCAGACUACC------------------------------------------------ 51 0,-5 -----CCCAGUGUUCAGACUACCU----------------------------------------------- 92 0,-4 -----CCCAGUGUUCAGACUACCUa---------------------------------------------- 2 0,-4 -----CCCAGUGUUCAGACUACCUau--------------------------------------------- 5 0,-4 -----CCCAGUGUUCAGACUACCUG---------------------------------------------- 109 0,-3 -----CCCAGUGUUCAGACUACCUGa--------------------------------------------- 36 0,-3 -----CCCAGUGUUCAGACUACCUGau-------------------------------------------- 2 0,-3 -----CCCAGUGUUCAGACUACCUGc--------------------------------------------- 6 0,-3 -----CCCAGUGUUCAGACUACCUGg--------------------------------------------- 2 0,-3 -----CCCAGUGUUCAGACUACCUGU--------------------------------------------- 2151 0,-2 -----CCCAGUGUUCAGACUACCUGUa-------------------------------------------- 36 0,-2 -----CCCAGUGUUCAGACUACCUGUaa------------------------------------------- 4 0,-2 -----CCCAGUGUUCAGACUACCUGUc-------------------------------------------- 12 0,-2 -----CCCAGUGUUCAGACUACCUGUg-------------------------------------------- 2 0,-2 -----CCCAGUGUUCAGACUACCUGUU-------------------------------------------- 7813 0,-1 -----CCCAGUGUUCAGACUACCUGUUa------------------------------------------- 97 0,-1 -----CCCAGUGUUCAGACUACCUGUUaa------------------------------------------ 2 0,-1 -----CCCAGUGUUCAGACUACCUGUUg------------------------------------------- 4 0,-1 -----CCCAGUGUUCAGACUACCUGUUu------------------------------------------- 444 0,-1 -----CCCAGUGUUCAGACUACCUGUUC------------------------------------------- 7390 0,0 -----CCCAGUGUUCAGACUACCUGUUCc------------------------------------------ 2 0,0 -----CCCAGUGUUCAGACUACCUGUUCg------------------------------------------ 17 0,0 -----CCCAGUGUUCAGACUACCUGUUCu------------------------------------------ 299 0,0 -----CCCAGUGUUCAGACUACCUGUUCA------------------------------------------ 156 0,1 ------CCAGUGUUCAGACUACCUGa--------------------------------------------- 2 1,-3 ------CCAGUGUUCAGACUACCUGU--------------------------------------------- 62 1,-2 ------CCAGUGUUCAGACUACCUGUU-------------------------------------------- 245 1,-1 ------CCAGUGUUCAGACUACCUGUUu------------------------------------------- 9 1,-1 ------CCAGUGUUCAGACUACCUGUUC------------------------------------------- 186 1,0 ------CCAGUGUUCAGACUACCUGUUCu------------------------------------------ 5 1,0 -------CAGUGUUCAGACUACCUGU--------------------------------------------- 2 2,-2 -------CAGUGUUCAGACUACCUGUU-------------------------------------------- 13 2,-1 -------CAGUGUUCAGACUACCUGUUu------------------------------------------- 2 2,-1 -------CAGUGUUCAGACUACCUGUUC------------------------------------------- 14 2,0 ---------------------------------------------UACAGUAGUCUGCACAUU-------- 2 -1,-5 ---------------------------------------------UACAGUAGUCUGCACAUUGa------ 2 -1,-4 ---------------------------------------------UACAGUAGUCUGCACAUUGG------ 16 -1,-3 ---------------------------------------------UACAGUAGUCUGCACAUUGGa----- 2 -1,-3 ---------------------------------------------UACAGUAGUCUGCACAUUGGU----- 223 -1,-2 ---------------------------------------------UACAGUAGUCUGCACAUUGGUa---- 25 -1,-2 ---------------------------------------------UACAGUAGUCUGCACAUUGGUaa--- 33 -1,-2 ---------------------------------------------UACAGUAGUCUGCACAUUGGUau--- 4 -1,-2 ---------------------------------------------UACAGUAGUCUGCACAUUGGUU---- 953 -1,-1 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUg--- 5 -1,-1 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUu--- 150 -1,-1 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUuu-- 9 -1,-1 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUA--- 169 -1,0 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUAa-- 21 -1,0 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUAu-- 19 -1,0 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUAG-- 2 -1,1 ----------------------------------------------ACAGUAGUCUGCACAUUG------- 223 0,-4 ----------------------------------------------ACAGUAGUCUGCACAUUGa------ 41 0,-4 ----------------------------------------------ACAGUAGUCUGCACAUUGaa----- 9 0,-4 ----------------------------------------------ACAGUAGUCUGCACAUUGau----- 2 0,-4 ----------------------------------------------ACAGUAGUCUGCACAUUGu------ 22 0,-4 ----------------------------------------------ACAGUAGUCUGCACAUUGuu----- 5 0,-4 ----------------------------------------------ACAGUAGUCUGCACAUUGG------ 404 0,-3 ----------------------------------------------ACAGUAGUCUGCACAUUGGa----- 67 0,-3 ----------------------------------------------ACAGUAGUCUGCACAUUGGaa---- 23 0,-3 ----------------------------------------------ACAGUAGUCUGCACAUUGGau---- 7 0,-3 ----------------------------------------------ACAGUAGUCUGCACAUUGGc----- 5 0,-3 ----------------------------------------------ACAGUAGUCUGCACAUUGGg----- 3 0,-3 ----------------------------------------------ACAGUAGUCUGCACAUUGGU----- 1716 0,-2 ----------------------------------------------ACAGUAGUCUGCACAUUGGUa---- 130 0,-2 ----------------------------------------------ACAGUAGUCUGCACAUUGGUaa--- 268 0,-2 ----------------------------------------------ACAGUAGUCUGCACAUUGGUau--- 16 0,-2 ----------------------------------------------ACAGUAGUCUGCACAUUGGUc---- 25 0,-2 ----------------------------------------------ACAGUAGUCUGCACAUUGGUg---- 2 0,-2 ----------------------------------------------ACAGUAGUCUGCACAUUGGUU---- 19145 0,-1 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUc--- 34 0,-1 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUg--- 71 0,-1 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUu--- 3065 0,-1 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUuu-- 151 0,-1 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUA--- 8194 0,0 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUAa-- 3312 0,0 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUAaa- 55 0,0 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUAau- 10 0,0 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUAc-- 12 0,0 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUAu-- 669 0,0 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUAG-- 67 0,1 -----------------------------------------------CAGUAGUCUGCACAUUGG------ 24 1,-3 -----------------------------------------------CAGUAGUCUGCACAUUGGa----- 5 1,-3 -----------------------------------------------CAGUAGUCUGCACAUUGGaa---- 2 1,-3 -----------------------------------------------CAGUAGUCUGCACAUUGGau---- 2 1,-3 -----------------------------------------------CAGUAGUCUGCACAUUGGU----- 137 1,-2 -----------------------------------------------CAGUAGUCUGCACAUUGGUa---- 18 1,-2 -----------------------------------------------CAGUAGUCUGCACAUUGGUaa--- 34 1,-2 -----------------------------------------------CAGUAGUCUGCACAUUGGUU---- 1659 1,-1 -----------------------------------------------CAGUAGUCUGCACAUUGGUUu--- 212 1,-1 -----------------------------------------------CAGUAGUCUGCACAUUGGUUuu-- 22 1,-1 -----------------------------------------------CAGUAGUCUGCACAUUGGUUA--- 826 1,0 -----------------------------------------------CAGUAGUCUGCACAUUGGUUAa-- 364 1,0 -----------------------------------------------CAGUAGUCUGCACAUUGGUUAaa- 23 1,0 -----------------------------------------------CAGUAGUCUGCACAUUGGUUAau- 7 1,0 -----------------------------------------------CAGUAGUCUGCACAUUGGUUAu-- 69 1,0 ------------------------------------------------AGUAGUCUGCACAUUGGU----- 4 2,-2 ------------------------------------------------AGUAGUCUGCACAUUGGUaa--- 2 2,-2 ------------------------------------------------AGUAGUCUGCACAUUGGUU---- 73 2,-1 ------------------------------------------------AGUAGUCUGCACAUUGGUUu--- 12 2,-1 ------------------------------------------------AGUAGUCUGCACAUUGGUUA--- 41 2,0 ------------------------------------------------AGUAGUCUGCACAUUGGUUAa-- 28 2,0 ------------------------------------------------AGUAGUCUGCACAUUGGUUAu-- 2 2,0 >hsa-mir-199a-2 5p:31-53;3p:70-91 Normal aggaagcuucuggagauccugcuccgucgcCCCAGUGUUCAGACUACCUGUUCaggacaaugccguuguACAGUAGUCUGCACAUUGGUUAgacugggcaagggagagca -----------------------------CCCCAGUGUUCAGACUACCUGUU---------------------------------------------------------- 3 -1,-1 ------------------------------CCCAGUGUUCAGACUACC-------------------------------------------------------------- 51 0,-5 ------------------------------CCCAGUGUUCAGACUACCU------------------------------------------------------------- 92 0,-4 ------------------------------CCCAGUGUUCAGACUACCUa------------------------------------------------------------ 2 0,-4 ------------------------------CCCAGUGUUCAGACUACCUau----------------------------------------------------------- 5 0,-4 ------------------------------CCCAGUGUUCAGACUACCUG------------------------------------------------------------ 109 0,-3 ------------------------------CCCAGUGUUCAGACUACCUGa----------------------------------------------------------- 36 0,-3 ------------------------------CCCAGUGUUCAGACUACCUGau---------------------------------------------------------- 2 0,-3 ------------------------------CCCAGUGUUCAGACUACCUGc----------------------------------------------------------- 6 0,-3 ------------------------------CCCAGUGUUCAGACUACCUGg----------------------------------------------------------- 2 0,-3 ------------------------------CCCAGUGUUCAGACUACCUGU----------------------------------------------------------- 2151 0,-2 ------------------------------CCCAGUGUUCAGACUACCUGUa---------------------------------------------------------- 36 0,-2 ------------------------------CCCAGUGUUCAGACUACCUGUaa--------------------------------------------------------- 4 0,-2 ------------------------------CCCAGUGUUCAGACUACCUGUc---------------------------------------------------------- 12 0,-2 ------------------------------CCCAGUGUUCAGACUACCUGUg---------------------------------------------------------- 2 0,-2 ------------------------------CCCAGUGUUCAGACUACCUGUU---------------------------------------------------------- 7813 0,-1 ------------------------------CCCAGUGUUCAGACUACCUGUUa--------------------------------------------------------- 97 0,-1 ------------------------------CCCAGUGUUCAGACUACCUGUUaa-------------------------------------------------------- 2 0,-1 ------------------------------CCCAGUGUUCAGACUACCUGUUg--------------------------------------------------------- 4 0,-1 ------------------------------CCCAGUGUUCAGACUACCUGUUu--------------------------------------------------------- 444 0,-1 ------------------------------CCCAGUGUUCAGACUACCUGUUC--------------------------------------------------------- 7390 0,0 ------------------------------CCCAGUGUUCAGACUACCUGUUCc-------------------------------------------------------- 2 0,0 ------------------------------CCCAGUGUUCAGACUACCUGUUCg-------------------------------------------------------- 17 0,0 ------------------------------CCCAGUGUUCAGACUACCUGUUCu-------------------------------------------------------- 299 0,0 ------------------------------CCCAGUGUUCAGACUACCUGUUCA-------------------------------------------------------- 156 0,1 -------------------------------CCAGUGUUCAGACUACCUGa----------------------------------------------------------- 2 1,-3 -------------------------------CCAGUGUUCAGACUACCUGU----------------------------------------------------------- 62 1,-2 -------------------------------CCAGUGUUCAGACUACCUGUU---------------------------------------------------------- 245 1,-1 -------------------------------CCAGUGUUCAGACUACCUGUUu--------------------------------------------------------- 9 1,-1 -------------------------------CCAGUGUUCAGACUACCUGUUC--------------------------------------------------------- 186 1,0 -------------------------------CCAGUGUUCAGACUACCUGUUCu-------------------------------------------------------- 5 1,0 --------------------------------CAGUGUUCAGACUACCUGU----------------------------------------------------------- 2 2,-2 --------------------------------CAGUGUUCAGACUACCUGUU---------------------------------------------------------- 13 2,-1 --------------------------------CAGUGUUCAGACUACCUGUUu--------------------------------------------------------- 2 2,-1 --------------------------------CAGUGUUCAGACUACCUGUUC--------------------------------------------------------- 14 2,0 --------------------------------------------------------------------UACAGUAGUCUGCACAUU------------------------ 2 -1,-5 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGa---------------------- 2 -1,-4 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGG---------------------- 16 -1,-3 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGa--------------------- 2 -1,-3 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGU--------------------- 223 -1,-2 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUa-------------------- 25 -1,-2 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUaa------------------- 33 -1,-2 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUau------------------- 4 -1,-2 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUU-------------------- 953 -1,-1 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUg------------------- 5 -1,-1 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUu------------------- 150 -1,-1 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUuu------------------ 9 -1,-1 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUA------------------- 169 -1,0 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAa------------------ 21 -1,0 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAu------------------ 19 -1,0 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAG------------------ 2 -1,1 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUG----------------------- 223 0,-4 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGa---------------------- 41 0,-4 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGaa--------------------- 9 0,-4 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGau--------------------- 2 0,-4 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGu---------------------- 22 0,-4 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGuu--------------------- 5 0,-4 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGG---------------------- 404 0,-3 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGa--------------------- 67 0,-3 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGaa-------------------- 23 0,-3 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGau-------------------- 7 0,-3 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGc--------------------- 5 0,-3 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGg--------------------- 3 0,-3 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGU--------------------- 1716 0,-2 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUa-------------------- 130 0,-2 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUaa------------------- 268 0,-2 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUau------------------- 16 0,-2 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUc-------------------- 25 0,-2 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUg-------------------- 2 0,-2 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUU-------------------- 19145 0,-1 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUc------------------- 34 0,-1 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUg------------------- 71 0,-1 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUu------------------- 3065 0,-1 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUuu------------------ 151 0,-1 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUA------------------- 8194 0,0 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAa------------------ 3312 0,0 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAaa----------------- 55 0,0 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAau----------------- 10 0,0 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAc------------------ 12 0,0 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAu------------------ 669 0,0 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAG------------------ 67 0,1 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAGA----------------- 2 0,2 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGG---------------------- 24 1,-3 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGa--------------------- 5 1,-3 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGaa-------------------- 2 1,-3 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGau-------------------- 2 1,-3 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGU--------------------- 137 1,-2 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUa-------------------- 18 1,-2 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUaa------------------- 34 1,-2 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUU-------------------- 1659 1,-1 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUu------------------- 212 1,-1 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUuu------------------ 22 1,-1 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUA------------------- 826 1,0 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAa------------------ 364 1,0 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAaa----------------- 23 1,0 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAau----------------- 7 1,0 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAu------------------ 69 1,0 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGU--------------------- 4 2,-2 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUaa------------------- 2 2,-2 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUU-------------------- 73 2,-1 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUUu------------------- 12 2,-1 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUUA------------------- 41 2,0 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUUAa------------------ 28 2,0 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUUAu------------------ 2 2,0 >hsa-mir-199b 5p:26-48;3p:65-86 Normal ccagaggacaccuccacuccgucuaCCCAGUGUUUAGACUAUCUGUUCaggacucccaaauuguACAGUAGUCUGCACAUUGGUUAggcugggcuggguuagacccucgg -------------------------CCCAGUGUUUAGACUAUC------------------------------------------------------------------- 13 0,-5 -------------------------CCCAGUGUUUAGACUAUCU------------------------------------------------------------------ 45 0,-4 -------------------------CCCAGUGUUUAGACUAUCUG----------------------------------------------------------------- 23 0,-3 -------------------------CCCAGUGUUUAGACUAUCUGa---------------------------------------------------------------- 9 0,-3 -------------------------CCCAGUGUUUAGACUAUCUGU---------------------------------------------------------------- 458 0,-2 -------------------------CCCAGUGUUUAGACUAUCUGUa--------------------------------------------------------------- 5 0,-2 -------------------------CCCAGUGUUUAGACUAUCUGUaa-------------------------------------------------------------- 5 0,-2 -------------------------CCCAGUGUUUAGACUAUCUGUc--------------------------------------------------------------- 2 0,-2 -------------------------CCCAGUGUUUAGACUAUCUGUU--------------------------------------------------------------- 1729 0,-1 -------------------------CCCAGUGUUUAGACUAUCUGUUa-------------------------------------------------------------- 104 0,-1 -------------------------CCCAGUGUUUAGACUAUCUGUUaa------------------------------------------------------------- 2 0,-1 -------------------------CCCAGUGUUUAGACUAUCUGUUu-------------------------------------------------------------- 44 0,-1 -------------------------CCCAGUGUUUAGACUAUCUGUUC-------------------------------------------------------------- 1805 0,0 -------------------------CCCAGUGUUUAGACUAUCUGUUCu------------------------------------------------------------- 34 0,0 -------------------------CCCAGUGUUUAGACUAUCUGUUCA------------------------------------------------------------- 44 0,1 --------------------------CCAGUGUUUAGACUAUCU------------------------------------------------------------------ 2 1,-4 --------------------------CCAGUGUUUAGACUAUCUGU---------------------------------------------------------------- 10 1,-2 --------------------------CCAGUGUUUAGACUAUCUGUU--------------------------------------------------------------- 65 1,-1 --------------------------CCAGUGUUUAGACUAUCUGUUa-------------------------------------------------------------- 2 1,-1 --------------------------CCAGUGUUUAGACUAUCUGUUu-------------------------------------------------------------- 2 1,-1 --------------------------CCAGUGUUUAGACUAUCUGUUC-------------------------------------------------------------- 63 1,0 ---------------------------CAGUGUUUAGACUAUCUGU---------------------------------------------------------------- 2 2,-2 ---------------------------CAGUGUUUAGACUAUCUGUU--------------------------------------------------------------- 11 2,-1 ---------------------------CAGUGUUUAGACUAUCUGUUC-------------------------------------------------------------- 2 2,0 ---------------------------------------------------------------UACAGUAGUCUGCACAUU----------------------------- 2 -1,-5 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGa--------------------------- 2 -1,-4 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGG--------------------------- 16 -1,-3 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGa-------------------------- 2 -1,-3 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGU-------------------------- 223 -1,-2 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUa------------------------- 25 -1,-2 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUaa------------------------ 33 -1,-2 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUau------------------------ 4 -1,-2 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUU------------------------- 953 -1,-1 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUg------------------------ 5 -1,-1 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUu------------------------ 150 -1,-1 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUuu----------------------- 9 -1,-1 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUA------------------------ 169 -1,0 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAa----------------------- 21 -1,0 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAu----------------------- 19 -1,0 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAG----------------------- 2 -1,1 ----------------------------------------------------------------ACAGUAGUCUGCACAUUG---------------------------- 223 0,-4 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGa--------------------------- 41 0,-4 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGaa-------------------------- 9 0,-4 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGau-------------------------- 2 0,-4 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGu--------------------------- 22 0,-4 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGuu-------------------------- 5 0,-4 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGG--------------------------- 404 0,-3 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGa-------------------------- 67 0,-3 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGaa------------------------- 23 0,-3 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGau------------------------- 7 0,-3 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGc-------------------------- 5 0,-3 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGg-------------------------- 3 0,-3 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGU-------------------------- 1716 0,-2 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUa------------------------- 130 0,-2 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUaa------------------------ 268 0,-2 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUau------------------------ 16 0,-2 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUc------------------------- 25 0,-2 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUg------------------------- 2 0,-2 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUU------------------------- 19145 0,-1 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUc------------------------ 34 0,-1 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUg------------------------ 71 0,-1 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUu------------------------ 3065 0,-1 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUuu----------------------- 151 0,-1 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUA------------------------ 8194 0,0 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAa----------------------- 3312 0,0 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAaa---------------------- 55 0,0 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAau---------------------- 10 0,0 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAc----------------------- 12 0,0 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAu----------------------- 669 0,0 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAG----------------------- 67 0,1 -----------------------------------------------------------------CAGUAGUCUGCACAUUGG--------------------------- 24 1,-3 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGa-------------------------- 5 1,-3 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGaa------------------------- 2 1,-3 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGau------------------------- 2 1,-3 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGU-------------------------- 137 1,-2 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUa------------------------- 18 1,-2 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUaa------------------------ 34 1,-2 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUU------------------------- 1659 1,-1 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUu------------------------ 212 1,-1 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUuu----------------------- 22 1,-1 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUA------------------------ 826 1,0 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAa----------------------- 364 1,0 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAaa---------------------- 23 1,0 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAau---------------------- 7 1,0 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAu----------------------- 69 1,0 ------------------------------------------------------------------AGUAGUCUGCACAUUGGU-------------------------- 4 2,-2 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUaa------------------------ 2 2,-2 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUU------------------------- 73 2,-1 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUUu------------------------ 12 2,-1 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUUA------------------------ 41 2,0 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUUAa----------------------- 28 2,0 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUUAu----------------------- 2 2,0 >hsa-mir-19a mi:14-35;MA:49-71 Normal gcaguccucuguuAGUUUUGCAUAGUUGCACUACAagaagaauguaguUGUGCAAAUCUAUGCAAAACUGAugguggccugc -----------------------------------------------UUGUGCAAAUCUAUGCAAAAC-------------- 7 -1,-3 -----------------------------------------------UUGUGCAAAUCUAUGCAAAACU------------- 31 -1,-2 -----------------------------------------------UUGUGCAAAUCUAUGCAAAACUG------------ 32 -1,-1 -----------------------------------------------UUGUGCAAAUCUAUGCAAAACUGA----------- 23 -1,0 ------------------------------------------------UGUGCAAAUCUAUGCAAA---------------- 2 0,-5 ------------------------------------------------UGUGCAAAUCUAUGCAAAA--------------- 12 0,-4 ------------------------------------------------UGUGCAAAUCUAUGCAAAAa-------------- 3 0,-4 ------------------------------------------------UGUGCAAAUCUAUGCAAAAC-------------- 51 0,-3 ------------------------------------------------UGUGCAAAUCUAUGCAAAACU------------- 165 0,-2 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUaa----------- 2 0,-2 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUG------------ 466 0,-1 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUGg----------- 3 0,-1 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUGu----------- 48 0,-1 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUGA----------- 1365 0,0 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUGAU---------- 12 0,1 -------------------------------------------------GUGCAAAUCUAUGCAAAACU------------- 3 1,-2 -------------------------------------------------GUGCAAAUCUAUGCAAAACUG------------ 19 1,-1 -------------------------------------------------GUGCAAAUCUAUGCAAAACUGA----------- 39 1,0 >hsa-mir-19b-1 mi:16-38;MA:54-76 Normal cacuguucuaugguuAGUUUUGCAGGUUUGCAUCCAGCugugugauauucugcUGUGCAAAUCCAUGCAAAACUGAcugugguagug ---------------AGUUUUGCAGGUUUGCAUCC---------------------------------------------------- 2 0,-3 ---------------AGUUUUGCAGGUUUGCAUCCA--------------------------------------------------- 2 0,-2 ---------------AGUUUUGCAGGUUUGCAUCCAG-------------------------------------------------- 5 0,-1 ---------------AGUUUUGCAGGUUUGCAUCCAGa------------------------------------------------- 6 0,-1 ---------------AGUUUUGCAGGUUUGCAUCCAGu------------------------------------------------- 8 0,-1 ---------------AGUUUUGCAGGUUUGCAUCCAGC------------------------------------------------- 44 0,0 ---------------AGUUUUGCAGGUUUGCAUCCAGCa------------------------------------------------ 2 0,0 ----------------------------------------------------CUGUGCAAAUCCAUGCAAAA--------------- 5 -1,-4 ----------------------------------------------------CUGUGCAAAUCCAUGCAAAAC-------------- 9 -1,-3 ----------------------------------------------------CUGUGCAAAUCCAUGCAAAACU------------- 46 -1,-2 ----------------------------------------------------CUGUGCAAAUCCAUGCAAAACUG------------ 100 -1,-1 ----------------------------------------------------CUGUGCAAAUCCAUGCAAAACUGu----------- 4 -1,-1 ----------------------------------------------------CUGUGCAAAUCCAUGCAAAACUGA----------- 70 -1,0 -----------------------------------------------------UGUGCAAAUCCAUGCAAA---------------- 256 0,-5 -----------------------------------------------------UGUGCAAAUCCAUGCAAAg--------------- 5 0,-5 -----------------------------------------------------UGUGCAAAUCCAUGCAAAA--------------- 237 0,-4 -----------------------------------------------------UGUGCAAAUCCAUGCAAAAa-------------- 62 0,-4 -----------------------------------------------------UGUGCAAAUCCAUGCAAAAaa------------- 6 0,-4 -----------------------------------------------------UGUGCAAAUCCAUGCAAAAg-------------- 2 0,-4 -----------------------------------------------------UGUGCAAAUCCAUGCAAAAu-------------- 2 0,-4 -----------------------------------------------------UGUGCAAAUCCAUGCAAAAC-------------- 1013 0,-3 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACa------------- 20 0,-3 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACaa------------ 2 0,-3 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACc------------- 7 0,-3 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACg------------- 3 0,-3 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACU------------- 3980 0,-2 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUa------------ 37 0,-2 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUaa----------- 21 0,-2 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUc------------ 5 0,-2 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUu------------ 9 0,-2 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUG------------ 12637 0,-1 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGc----------- 37 0,-1 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGg----------- 20 0,-1 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGu----------- 940 0,-1 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGuu---------- 2 0,-1 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGA----------- 13670 0,0 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGAa---------- 41 0,0 ------------------------------------------------------GUGCAAAUCCAUGCAAAA--------------- 11 1,-4 ------------------------------------------------------GUGCAAAUCCAUGCAAAAa-------------- 2 1,-4 ------------------------------------------------------GUGCAAAUCCAUGCAAAAC-------------- 19 1,-3 ------------------------------------------------------GUGCAAAUCCAUGCAAAACa------------- 3 1,-3 ------------------------------------------------------GUGCAAAUCCAUGCAAAACU------------- 162 1,-2 ------------------------------------------------------GUGCAAAUCCAUGCAAAACUG------------ 658 1,-1 ------------------------------------------------------GUGCAAAUCCAUGCAAAACUGu----------- 51 1,-1 ------------------------------------------------------GUGCAAAUCCAUGCAAAACUGA----------- 273 1,0 >hsa-mir-19b-2 mi:19-40;MA:62-84 Normal acauugcuacuuacaauuAGUUUUGCAGGUUUGCAUUUCAgcguauauauguauauguggcUGUGCAAAUCCAUGCAAAACUGAuugugauaaugu ------------------------------------------------------------CUGUGCAAAUCCAUGCAAAA---------------- 5 -1,-4 ------------------------------------------------------------CUGUGCAAAUCCAUGCAAAAC--------------- 9 -1,-3 ------------------------------------------------------------CUGUGCAAAUCCAUGCAAAACU-------------- 46 -1,-2 ------------------------------------------------------------CUGUGCAAAUCCAUGCAAAACUG------------- 100 -1,-1 ------------------------------------------------------------CUGUGCAAAUCCAUGCAAAACUGu------------ 4 -1,-1 ------------------------------------------------------------CUGUGCAAAUCCAUGCAAAACUGA------------ 70 -1,0 -------------------------------------------------------------UGUGCAAAUCCAUGCAAA----------------- 256 0,-5 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAg---------------- 5 0,-5 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAA---------------- 237 0,-4 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAAa--------------- 62 0,-4 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAAaa-------------- 6 0,-4 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAAg--------------- 2 0,-4 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAAu--------------- 2 0,-4 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAAC--------------- 1013 0,-3 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACa-------------- 20 0,-3 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACaa------------- 2 0,-3 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACc-------------- 7 0,-3 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACg-------------- 3 0,-3 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACU-------------- 3980 0,-2 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUa------------- 37 0,-2 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUaa------------ 21 0,-2 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUc------------- 5 0,-2 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUu------------- 9 0,-2 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUG------------- 12637 0,-1 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGc------------ 37 0,-1 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGg------------ 20 0,-1 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGu------------ 940 0,-1 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGuu----------- 2 0,-1 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGA------------ 13670 0,0 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGAa----------- 41 0,0 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGAU----------- 38 0,1 --------------------------------------------------------------GUGCAAAUCCAUGCAAAA---------------- 11 1,-4 --------------------------------------------------------------GUGCAAAUCCAUGCAAAAa--------------- 2 1,-4 --------------------------------------------------------------GUGCAAAUCCAUGCAAAAC--------------- 19 1,-3 --------------------------------------------------------------GUGCAAAUCCAUGCAAAACa-------------- 3 1,-3 --------------------------------------------------------------GUGCAAAUCCAUGCAAAACU-------------- 162 1,-2 --------------------------------------------------------------GUGCAAAUCCAUGCAAAACUG------------- 658 1,-1 --------------------------------------------------------------GUGCAAAUCCAUGCAAAACUGu------------ 51 1,-1 --------------------------------------------------------------GUGCAAAUCCAUGCAAAACUGA------------ 273 1,0 >hsa-mir-200a mi:16-37;MA:54-75 Normal ccgggccccugugagCAUCUUACCGGACAGUGCUGGAuuucccagcuugacucUAACACUGUCUGGUAACGAUGUucaaaggugacccgc ---------------CAUCUUACCGGACAGUGCUGGA----------------------------------------------------- 5 0,0 ----------------------------------------------------CUAACACUGUCUGGUAACGAUGUU-------------- 3 -1,1 -----------------------------------------------------UAACACUGUCUGGUAACG------------------- 6 0,-4 -----------------------------------------------------UAACACUGUCUGGUAACGA------------------ 18 0,-3 -----------------------------------------------------UAACACUGUCUGGUAACGAU----------------- 66 0,-2 -----------------------------------------------------UAACACUGUCUGGUAACGAUa---------------- 20 0,-2 -----------------------------------------------------UAACACUGUCUGGUAACGAUG---------------- 282 0,-1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGa--------------- 62 0,-1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGaa-------------- 5 0,-1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGg--------------- 15 0,-1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGU--------------- 798 0,0 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUa-------------- 8 0,0 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUaa------------- 2 0,0 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUc-------------- 4 0,0 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUU-------------- 1370 0,1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUUa------------- 18 0,1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUUu------------- 118 0,1 ------------------------------------------------------AACACUGUCUGGUAACGAUG---------------- 8 1,-1 ------------------------------------------------------AACACUGUCUGGUAACGAUGU--------------- 46 1,0 ------------------------------------------------------AACACUGUCUGGUAACGAUGUU-------------- 82 1,1 ------------------------------------------------------AACACUGUCUGGUAACGAUGUUu------------- 19 1,1 -------------------------------------------------------ACACUGUCUGGUAACGAUGU--------------- 2 2,0 -------------------------------------------------------ACACUGUCUGGUAACGAUGUU-------------- 5 2,1 >hsa-mir-200b mi:21-42;MA:57-78 Normal ccagcucgggcagccguggcCAUCUUACUGGGCAGCAUUGGAuggagucaggucucUAAUACUGCCUGGUAAUGAUGAcggcggagcccugcacg --------------------CAUCUUACUGGGCAGCAUUGG------------------------------------------------------ 10 0,-1 --------------------CAUCUUACUGGGCAGCAUUGGA----------------------------------------------------- 40 0,0 --------------------CAUCUUACUGGGCAGCAUUGGAa---------------------------------------------------- 5 0,0 ---------------------AUCUUACUGGGCAGCAUUGGA----------------------------------------------------- 3 1,0 -------------------------------------------------------CUAAUACUGCCUGGUAAUGAUG------------------ 3 -1,-1 --------------------------------------------------------UAAUACUGCCUGGUAAUG--------------------- 11 0,-4 --------------------------------------------------------UAAUACUGCCUGGUAAUGu-------------------- 2 0,-4 --------------------------------------------------------UAAUACUGCCUGGUAAUGA-------------------- 131 0,-3 --------------------------------------------------------UAAUACUGCCUGGUAAUGAa------------------- 30 0,-3 --------------------------------------------------------UAAUACUGCCUGGUAAUGAaa------------------ 49 0,-3 --------------------------------------------------------UAAUACUGCCUGGUAAUGAau------------------ 6 0,-3 --------------------------------------------------------UAAUACUGCCUGGUAAUGAU------------------- 157 0,-2 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUa------------------ 34 0,-2 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUaa----------------- 8 0,-2 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUu------------------ 26 0,-2 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUG------------------ 615 0,-1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGu----------------- 72 0,-1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGuu---------------- 3 0,-1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGA----------------- 974 0,0 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGAa---------------- 76 0,0 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGAaa--------------- 3 0,0 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGAau--------------- 2 0,0 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGAu---------------- 34 0,0 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGAuu--------------- 2 0,0 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGAC---------------- 523 0,1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGACa--------------- 50 0,1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGACu--------------- 153 0,1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGACG--------------- 2 0,2 ---------------------------------------------------------AAUACUGCCUGGUAAUGA-------------------- 6 1,-3 ---------------------------------------------------------AAUACUGCCUGGUAAUGAU------------------- 4 1,-2 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUG------------------ 41 1,-1 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGA----------------- 82 1,0 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGAa---------------- 15 1,0 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGAaa--------------- 4 1,0 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGAuu--------------- 3 1,0 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGAC---------------- 99 1,1 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGACa--------------- 83 1,1 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGACc--------------- 7 1,1 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGACu--------------- 424 1,1 ----------------------------------------------------------AUACUGCCUGGUAAUGAUGAC---------------- 3 2,1 ----------------------------------------------------------AUACUGCCUGGUAAUGAUGACu--------------- 49 2,1 ----------------------------------------------------------AUACUGCCUGGUAAUGAUGACuu-------------- 10 2,1 >hsa-mir-200c mi:5-26;MA:44-66 Normal cccuCGUCUUACCCAGCAGUGUUUGGgugcgguugggagucucUAAUACUGCCGGGUAAUGAUGGAgg ----CGUCUUACCCAGCAGUGUUUGG------------------------------------------ 6 0,0 ------------------------------------------CUAAUACUGCCGGGUAAUGA------ 2 -1,-4 ------------------------------------------CUAAUACUGCCGGGUAAUGAaa---- 2 -1,-4 ------------------------------------------CUAAUACUGCCGGGUAAUGAU----- 9 -1,-3 ------------------------------------------CUAAUACUGCCGGGUAAUGAUG---- 14 -1,-2 ------------------------------------------CUAAUACUGCCGGGUAAUGAUGG--- 5 -1,-1 ------------------------------------------CUAAUACUGCCGGGUAAUGAUGGA-- 3 -1,0 -------------------------------------------UAAUACUGCCGGGUAAUG------- 17 0,-5 -------------------------------------------UAAUACUGCCGGGUAAUGu------ 3 0,-5 -------------------------------------------UAAUACUGCCGGGUAAUGuu----- 2 0,-5 -------------------------------------------UAAUACUGCCGGGUAAUGA------ 33 0,-4 -------------------------------------------UAAUACUGCCGGGUAAUGAa----- 13 0,-4 -------------------------------------------UAAUACUGCCGGGUAAUGAaa---- 3 0,-4 -------------------------------------------UAAUACUGCCGGGUAAUGAau---- 2 0,-4 -------------------------------------------UAAUACUGCCGGGUAAUGAU----- 119 0,-3 -------------------------------------------UAAUACUGCCGGGUAAUGAUa---- 18 0,-3 -------------------------------------------UAAUACUGCCGGGUAAUGAUau--- 2 0,-3 -------------------------------------------UAAUACUGCCGGGUAAUGAUu---- 6 0,-3 -------------------------------------------UAAUACUGCCGGGUAAUGAUG---- 297 0,-2 -------------------------------------------UAAUACUGCCGGGUAAUGAUGa--- 73 0,-2 -------------------------------------------UAAUACUGCCGGGUAAUGAUGaa-- 7 0,-2 -------------------------------------------UAAUACUGCCGGGUAAUGAUGu--- 38 0,-2 -------------------------------------------UAAUACUGCCGGGUAAUGAUGG--- 1033 0,-1 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGc-- 4 0,-1 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGg-- 2 0,-1 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGu-- 260 0,-1 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGuu- 10 0,-1 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGA-- 1940 0,0 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGAa- 112 0,0 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGAaa 2 0,0 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGAau 3 0,0 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGAu- 55 0,0 --------------------------------------------AAUACUGCCGGGUAAUGAU----- 7 1,-3 --------------------------------------------AAUACUGCCGGGUAAUGAUa---- 2 1,-3 --------------------------------------------AAUACUGCCGGGUAAUGAUG---- 11 1,-2 --------------------------------------------AAUACUGCCGGGUAAUGAUGa--- 4 1,-2 --------------------------------------------AAUACUGCCGGGUAAUGAUGu--- 3 1,-2 --------------------------------------------AAUACUGCCGGGUAAUGAUGG--- 34 1,-1 --------------------------------------------AAUACUGCCGGGUAAUGAUGGu-- 12 1,-1 --------------------------------------------AAUACUGCCGGGUAAUGAUGGA-- 85 1,0 --------------------------------------------AAUACUGCCGGGUAAUGAUGGAa- 2 1,0 ---------------------------------------------AUACUGCCGGGUAAUGAUGGA-- 6 2,0 >hsa-mir-202 mi:28-49;MA:64-83 Normal cgccucagagccgcccgccguuccuuuUUCCUAUGCAUAUACUUCUUUGaggaucuggccuaaAGAGGUAUAGGGCAUGGGAAaacggggcggucggguccuccccagcg ---------------------------UUCCUAUGCAUAUACUUCUU--------------------------------------------------------------- 2 0,-2 ---------------------------UUCCUAUGCAUAUACUUCUUU-------------------------------------------------------------- 4 0,-1 >hsa-mir-203 3pM:65-86 Normal guguuggggacucgcgcgcuggguccagugguucuuaacaguucaacaguucuguagcgcaauuGUGAAAUGUUUAGGACCACUAGacccggcgggcgcggcgacagcga --------------------------AGUGGUUCUUAACAGUUCA----------------------------------------------------------------- 2 --------------------------AGUGGUUCUUAACAGUUCAAC--------------------------------------------------------------- 3 --------------------------AGUGGUUCUUAACAGUUCAACA-------------------------------------------------------------- 2 ---------------------------------------------------------------UGUGAAAUGUUUAGGACCACU-------------------------- 2 -1,-2 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACU-------------------------- 56 0,-2 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUA------------------------- 16 0,-1 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAa------------------------ 10 0,-1 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAaa----------------------- 4 0,-1 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAu------------------------ 21 0,-1 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAG------------------------ 147 0,0 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAGu----------------------- 36 0,0 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAGA----------------------- 69 0,1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACU-------------------------- 5 1,-2 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUA------------------------- 2 1,-1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAaa----------------------- 2 1,-1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAu------------------------ 2 1,-1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAG------------------------ 44 1,0 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAGu----------------------- 77 1,0 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAGA----------------------- 46 1,1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAGAa---------------------- 6 1,1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAGAau--------------------- 2 1,1 ------------------------------------------------------------------GAAAUGUUUAGGACCACUAG------------------------ 2 2,0 >hsa-mir-204 5pM:33-54 Normal ggcuacagucuuucuucaugugacucguggacUUCCCUUUGUCAUCCUAUGCCUgagaauauaugaaggaggcugggaaggcaaagggacguucaauugucaucacuggc --------------------------------UUCCCUUUGUCAUCCUAUGCC--------------------------------------------------------- 12 0,-1 --------------------------------UUCCCUUUGUCAUCCUAUGCCa-------------------------------------------------------- 6 0,-1 --------------------------------UUCCCUUUGUCAUCCUAUGCCU-------------------------------------------------------- 94 0,0 --------------------------------UUCCCUUUGUCAUCCUAUGCCUu------------------------------------------------------- 10 0,0 --------------------------------UUCCCUUUGUCAUCCUAUGCCUG------------------------------------------------------- 6 0,1 --------------------------------UUCCCUUUGUCAUCCUAUGCCUGu------------------------------------------------------ 5 0,1 ---------------------------------UCCCUUUGUCAUCCUAUGCCU-------------------------------------------------------- 4 1,0 -----------------------------------------------------------------------GCUGGGAAGGCAAAGGGACG------------------- 3 -----------------------------------------------------------------------GCUGGGAAGGCAAAGGGACGU------------------ 5 >hsa-mir-205 MA:34-55;mi:71-91 Normal aaagauccucagacaauccaugugcuucucuugUCCUUCAUUCCACCGGAGUCUGucucauacccaaccaGAUUUCAGUGGAGUGAAGUUCaggaggcauggagcugaca ---------------------------------UCCUUCAUUCCACCGGAG----------------------------------------------------------- 266 0,-4 ---------------------------------UCCUUCAUUCCACCGGAGa---------------------------------------------------------- 43 0,-4 ---------------------------------UCCUUCAUUCCACCGGAGaa--------------------------------------------------------- 18 0,-4 ---------------------------------UCCUUCAUUCCACCGGAGU---------------------------------------------------------- 556 0,-3 ---------------------------------UCCUUCAUUCCACCGGAGUa--------------------------------------------------------- 3 0,-3 ---------------------------------UCCUUCAUUCCACCGGAGUaa-------------------------------------------------------- 19 0,-3 ---------------------------------UCCUUCAUUCCACCGGAGUau-------------------------------------------------------- 4 0,-3 ---------------------------------UCCUUCAUUCCACCGGAGUu--------------------------------------------------------- 4 0,-3 ---------------------------------UCCUUCAUUCCACCGGAGUC--------------------------------------------------------- 308 0,-2 ---------------------------------UCCUUCAUUCCACCGGAGUCa-------------------------------------------------------- 157 0,-2 ---------------------------------UCCUUCAUUCCACCGGAGUCaa------------------------------------------------------- 13 0,-2 ---------------------------------UCCUUCAUUCCACCGGAGUCau------------------------------------------------------- 4 0,-2 ---------------------------------UCCUUCAUUCCACCGGAGUCc-------------------------------------------------------- 11 0,-2 ---------------------------------UCCUUCAUUCCACCGGAGUCg-------------------------------------------------------- 5 0,-2 ---------------------------------UCCUUCAUUCCACCGGAGUCU-------------------------------------------------------- 8321 0,-1 ---------------------------------UCCUUCAUUCCACCGGAGUCUa------------------------------------------------------- 33 0,-1 ---------------------------------UCCUUCAUUCCACCGGAGUCUaa------------------------------------------------------ 8 0,-1 ---------------------------------UCCUUCAUUCCACCGGAGUCUau------------------------------------------------------ 13 0,-1 ---------------------------------UCCUUCAUUCCACCGGAGUCUc------------------------------------------------------- 7 0,-1 ---------------------------------UCCUUCAUUCCACCGGAGUCUu------------------------------------------------------- 99 0,-1 ---------------------------------UCCUUCAUUCCACCGGAGUCUuu------------------------------------------------------ 20 0,-1 ---------------------------------UCCUUCAUUCCACCGGAGUCUG------------------------------------------------------- 9466 0,0 ---------------------------------UCCUUCAUUCCACCGGAGUCUGa------------------------------------------------------ 3161 0,0 ---------------------------------UCCUUCAUUCCACCGGAGUCUGaa----------------------------------------------------- 41 0,0 ---------------------------------UCCUUCAUUCCACCGGAGUCUGau----------------------------------------------------- 15 0,0 ---------------------------------UCCUUCAUUCCACCGGAGUCUGc------------------------------------------------------ 47 0,0 ---------------------------------UCCUUCAUUCCACCGGAGUCUGg------------------------------------------------------ 27 0,0 ---------------------------------UCCUUCAUUCCACCGGAGUCUGU------------------------------------------------------ 6823 0,1 ---------------------------------UCCUUCAUUCCACCGGAGUCUGUa----------------------------------------------------- 53 0,1 ---------------------------------UCCUUCAUUCCACCGGAGUCUGUaa---------------------------------------------------- 2 0,1 ---------------------------------UCCUUCAUUCCACCGGAGUCUGUg----------------------------------------------------- 3 0,1 ---------------------------------UCCUUCAUUCCACCGGAGUCUGUu----------------------------------------------------- 131 0,1 ---------------------------------UCCUUCAUUCCACCGGAGUCUGUuu---------------------------------------------------- 11 0,1 ----------------------------------CCUUCAUUCCACCGGAGUCU-------------------------------------------------------- 4 1,-1 ----------------------------------CCUUCAUUCCACCGGAGUCUG------------------------------------------------------- 8 1,0 ----------------------------------CCUUCAUUCCACCGGAGUCUGaa----------------------------------------------------- 2 1,0 ----------------------------------CCUUCAUUCCACCGGAGUCUGU------------------------------------------------------ 2 1,1 -----------------------------------CUUCAUUCCACCGGAGUCU-------------------------------------------------------- 55 2,-1 -----------------------------------CUUCAUUCCACCGGAGUCUG------------------------------------------------------- 69 2,0 -----------------------------------CUUCAUUCCACCGGAGUCUGa------------------------------------------------------ 22 2,0 -----------------------------------CUUCAUUCCACCGGAGUCUGU------------------------------------------------------ 63 2,1 ----------------------------------------------------------------------GAUUUCAGUGGAGUGAAGUU-------------------- 2 0,-1 ----------------------------------------------------------------------GAUUUCAGUGGAGUGAAGUUa------------------- 2 0,-1 ----------------------------------------------------------------------GAUUUCAGUGGAGUGAAGUUu------------------- 2 0,-1 ----------------------------------------------------------------------GAUUUCAGUGGAGUGAAGUUC------------------- 85 0,0 ----------------------------------------------------------------------GAUUUCAGUGGAGUGAAGUUCu------------------ 12 0,0 ----------------------------------------------------------------------GAUUUCAGUGGAGUGAAGUUCA------------------ 121 0,1 -----------------------------------------------------------------------AUUUCAGUGGAGUGAAGUUC------------------- 2 1,0 -----------------------------------------------------------------------AUUUCAGUGGAGUGAAGUUCA------------------ 9 1,1 >hsa-mir-206 3pM:53-74 Normal ugcuucccgaggccacaugcuucuuuauauccccauauggauuacuuugcuaUGGAAUGUAAGGAAGUGUGUGGuuucggcaagug ----------------------------------------------------UGGAAUGUAAGGAAGUGUGUGG------------ 2 0,0 >hsa-mir-20a MA:8-30;mi:44-65 Normal guagcacUAAAGUGCUUAUAGUGCAGGUAGuguuuaguuaucuACUGCAUUAUGAGCACUUAAAGuacugc ------CUAAAGUGCUUAUAGUGCAGGU------------------------------------------- 2 -1,-2 ------CUAAAGUGCUUAUAGUGCAGGUA------------------------------------------ 2 -1,-1 -------UAAAGUGCUUAUAGUGCA---------------------------------------------- 8 0,-5 -------UAAAGUGCUUAUAGUGCAG--------------------------------------------- 9 0,-4 -------UAAAGUGCUUAUAGUGCAGG-------------------------------------------- 30 0,-3 -------UAAAGUGCUUAUAGUGCAGGa------------------------------------------- 9 0,-3 -------UAAAGUGCUUAUAGUGCAGGaa------------------------------------------ 3 0,-3 -------UAAAGUGCUUAUAGUGCAGGU------------------------------------------- 167 0,-2 -------UAAAGUGCUUAUAGUGCAGGUu------------------------------------------ 6 0,-2 -------UAAAGUGCUUAUAGUGCAGGUA------------------------------------------ 396 0,-1 -------UAAAGUGCUUAUAGUGCAGGUAa----------------------------------------- 135 0,-1 -------UAAAGUGCUUAUAGUGCAGGUAaa---------------------------------------- 2 0,-1 -------UAAAGUGCUUAUAGUGCAGGUAu----------------------------------------- 90 0,-1 -------UAAAGUGCUUAUAGUGCAGGUAG----------------------------------------- 955 0,0 -------UAAAGUGCUUAUAGUGCAGGUAGa---------------------------------------- 94 0,0 -------UAAAGUGCUUAUAGUGCAGGUAGaa--------------------------------------- 7 0,0 -------UAAAGUGCUUAUAGUGCAGGUAGg---------------------------------------- 2 0,0 -------UAAAGUGCUUAUAGUGCAGGUAGU---------------------------------------- 49 0,1 --------AAAGUGCUUAUAGUGCAGGU------------------------------------------- 10 1,-2 --------AAAGUGCUUAUAGUGCAGGUA------------------------------------------ 14 1,-1 --------AAAGUGCUUAUAGUGCAGGUAa----------------------------------------- 7 1,-1 --------AAAGUGCUUAUAGUGCAGGUAu----------------------------------------- 2 1,-1 --------AAAGUGCUUAUAGUGCAGGUAG----------------------------------------- 35 1,0 --------AAAGUGCUUAUAGUGCAGGUAGa---------------------------------------- 3 1,0 -------------------------------------------ACUGCAUUAUGAGCACUUAA-------- 10 0,-2 -------------------------------------------ACUGCAUUAUGAGCACUUAAA------- 11 0,-1 -------------------------------------------ACUGCAUUAUGAGCACUUAAAa------ 5 0,-1 -------------------------------------------ACUGCAUUAUGAGCACUUAAAG------ 30 0,0 -------------------------------------------ACUGCAUUAUGAGCACUUAAAGa----- 4 0,0 -------------------------------------------ACUGCAUUAUGAGCACUUAAAGU----- 38 0,1 --------------------------------------------CUGCAUUAUGAGCACUUAAAGU----- 8 1,1 >hsa-mir-20b MA:6-28;mi:44-65 Normal aguacCAAAGUGCUCAUAGUGCAGGUAGuuuuggcaugacucuACUGUAGUAUGGGCACUUCCAGuacu -----CAAAGUGCUCAUAGUGCA---------------------------------------------- 2 0,-5 -----CAAAGUGCUCAUAGUGCAGG-------------------------------------------- 5 0,-3 -----CAAAGUGCUCAUAGUGCAGGU------------------------------------------- 38 0,-2 -----CAAAGUGCUCAUAGUGCAGGUA------------------------------------------ 58 0,-1 -----CAAAGUGCUCAUAGUGCAGGUAa----------------------------------------- 4 0,-1 -----CAAAGUGCUCAUAGUGCAGGUAu----------------------------------------- 4 0,-1 -----CAAAGUGCUCAUAGUGCAGGUAG----------------------------------------- 66 0,0 -----CAAAGUGCUCAUAGUGCAGGUAGa---------------------------------------- 6 0,0 ------AAAGUGCUCAUAGUGCAGGUAG----------------------------------------- 2 1,0 ------AAAGUGCUCAUAGUGCAGGUAGa---------------------------------------- 2 1,0 >hsa-mir-21 MA:8-29;mi:46-66 Normal ugucgggUAGCUUAUCAGACUGAUGUUGAcuguugaaucucauggCAACACCAGUCGAUGGGCUGUcugaca ------GUAGCUUAUCAGACUGAUGUUG-------------------------------------------- 18 -1,-1 ------GUAGCUUAUCAGACUGAUGUUGA------------------------------------------- 17 -1,0 ------GUAGCUUAUCAGACUGAUGUUGAC------------------------------------------ 2 -1,1 -------UAGCUUAUCAGACUGAUG----------------------------------------------- 381 0,-4 -------UAGCUUAUCAGACUGAUGa---------------------------------------------- 15 0,-4 -------UAGCUUAUCAGACUGAUGaa--------------------------------------------- 5 0,-4 -------UAGCUUAUCAGACUGAUGU---------------------------------------------- 205 0,-3 -------UAGCUUAUCAGACUGAUGUa--------------------------------------------- 7 0,-3 -------UAGCUUAUCAGACUGAUGUaa-------------------------------------------- 18 0,-3 -------UAGCUUAUCAGACUGAUGUU--------------------------------------------- 955 0,-2 -------UAGCUUAUCAGACUGAUGUUa-------------------------------------------- 43 0,-2 -------UAGCUUAUCAGACUGAUGUUaa------------------------------------------- 45 0,-2 -------UAGCUUAUCAGACUGAUGUUu-------------------------------------------- 56 0,-2 -------UAGCUUAUCAGACUGAUGUUG-------------------------------------------- 7055 0,-1 -------UAGCUUAUCAGACUGAUGUUGc------------------------------------------- 29 0,-1 -------UAGCUUAUCAGACUGAUGUUGg------------------------------------------- 26 0,-1 -------UAGCUUAUCAGACUGAUGUUGu------------------------------------------- 55 0,-1 -------UAGCUUAUCAGACUGAUGUUGuu------------------------------------------ 2 0,-1 -------UAGCUUAUCAGACUGAUGUUGA------------------------------------------- 34903 0,0 -------UAGCUUAUCAGACUGAUGUUGAa------------------------------------------ 1636 0,0 -------UAGCUUAUCAGACUGAUGUUGAaa----------------------------------------- 84 0,0 -------UAGCUUAUCAGACUGAUGUUGAau----------------------------------------- 2 0,0 -------UAGCUUAUCAGACUGAUGUUGAg------------------------------------------ 27 0,0 -------UAGCUUAUCAGACUGAUGUUGAu------------------------------------------ 109 0,0 -------UAGCUUAUCAGACUGAUGUUGAuu----------------------------------------- 2 0,0 -------UAGCUUAUCAGACUGAUGUUGAC------------------------------------------ 21010 0,1 -------UAGCUUAUCAGACUGAUGUUGACa----------------------------------------- 1213 0,1 -------UAGCUUAUCAGACUGAUGUUGACaa---------------------------------------- 10 0,1 -------UAGCUUAUCAGACUGAUGUUGACc----------------------------------------- 34 0,1 -------UAGCUUAUCAGACUGAUGUUGACg----------------------------------------- 83 0,1 -------UAGCUUAUCAGACUGAUGUUGACU----------------------------------------- 596 0,2 --------AGCUUAUCAGACUGAUGU---------------------------------------------- 6 1,-3 --------AGCUUAUCAGACUGAUGUU--------------------------------------------- 21 1,-2 --------AGCUUAUCAGACUGAUGUUG-------------------------------------------- 293 1,-1 --------AGCUUAUCAGACUGAUGUUGu------------------------------------------- 2 1,-1 --------AGCUUAUCAGACUGAUGUUGA------------------------------------------- 1406 1,0 --------AGCUUAUCAGACUGAUGUUGAa------------------------------------------ 77 1,0 --------AGCUUAUCAGACUGAUGUUGAg------------------------------------------ 2 1,0 --------AGCUUAUCAGACUGAUGUUGAC------------------------------------------ 983 1,1 --------AGCUUAUCAGACUGAUGUUGACa----------------------------------------- 59 1,1 --------AGCUUAUCAGACUGAUGUUGACaa---------------------------------------- 2 1,1 --------AGCUUAUCAGACUGAUGUUGACg----------------------------------------- 2 1,1 --------AGCUUAUCAGACUGAUGUUGACU----------------------------------------- 22 1,2 ---------GCUUAUCAGACUGAUGUU--------------------------------------------- 2 2,-2 ---------GCUUAUCAGACUGAUGUUG-------------------------------------------- 12 2,-1 ---------GCUUAUCAGACUGAUGUUGA------------------------------------------- 85 2,0 ---------GCUUAUCAGACUGAUGUUGAa------------------------------------------ 5 2,0 ---------GCUUAUCAGACUGAUGUUGAC------------------------------------------ 64 2,1 ---------GCUUAUCAGACUGAUGUUGACa----------------------------------------- 4 2,1 ---------------------------------------------CAACACCAGUCGAUGGGC--------- 2 0,-3 ---------------------------------------------CAACACCAGUCGAUGGGCUG------- 2 0,-1 ---------------------------------------------CAACACCAGUCGAUGGGCUGU------ 97 0,0 ---------------------------------------------CAACACCAGUCGAUGGGCUGUaa---- 11 0,0 ---------------------------------------------CAACACCAGUCGAUGGGCUGUau---- 2 0,0 ---------------------------------------------CAACACCAGUCGAUGGGCUGUu----- 4 0,0 ---------------------------------------------CAACACCAGUCGAUGGGCUGUC----- 133 0,1 ---------------------------------------------CAACACCAGUCGAUGGGCUGUCa---- 38 0,1 ---------------------------------------------CAACACCAGUCGAUGGGCUGUCaa--- 3 0,1 ---------------------------------------------CAACACCAGUCGAUGGGCUGUCau--- 6 0,1 ---------------------------------------------CAACACCAGUCGAUGGGCUGUCU---- 22 0,2 ----------------------------------------------AACACCAGUCGAUGGGCUGU------ 4 1,0 ----------------------------------------------AACACCAGUCGAUGGGCUGUC----- 4 1,1 ----------------------------------------------AACACCAGUCGAUGGGCUGUCU---- 2 1,2 >hsa-mir-210 3pM:66-87 Normal acccggcagugccuccaggcgcagggcagccccugcccaccgcacacugcgcugccccagacccaCUGUGCGUGUGACAGCGGCUGAucugugccugggcagcgcgaccc ----------------------------------------------------------------ACUGUGCGUGUGACAGCGGCUGA----------------------- 13 -1,0 ----------------------------------------------------------------ACUGUGCGUGUGACAGCGGCUGAa---------------------- 3 -1,0 ----------------------------------------------------------------ACUGUGCGUGUGACAGCGGCUGAU---------------------- 4 -1,1 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGaa------------------------- 2 0,-4 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCU------------------------- 33 0,-2 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUG------------------------ 8 0,-1 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGA----------------------- 579 0,0 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAa---------------------- 116 0,0 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAaa--------------------- 55 0,0 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAau--------------------- 67 0,0 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAg---------------------- 7 0,0 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAU---------------------- 122 0,1 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAUu--------------------- 21 0,1 ------------------------------------------------------------------UGUGCGUGUGACAGCGGCUGA----------------------- 13 1,0 -------------------------------------------------------------------GUGCGUGUGACAGCGGCUGA----------------------- 2 2,0 >hsa-mir-2110 5pM:8-29 Normal cagggguUUGGGGAAACGGCCGCUGAGUGaggcgucggcuguguuucucaccgcggucuuuuccucccacucuug -------UUGGGGAAACGGCCGCUGAG------------------------------------------------ 4 0,-2 -------UUGGGGAAACGGCCGCUGAGU----------------------------------------------- 17 0,-1 -------UUGGGGAAACGGCCGCUGAGUG---------------------------------------------- 2 0,0 -------UUGGGGAAACGGCCGCUGAGUGu--------------------------------------------- 15 0,0 -------UUGGGGAAACGGCCGCUGAGUGA--------------------------------------------- 48 0,1 -------UUGGGGAAACGGCCGCUGAGUGAu-------------------------------------------- 2 0,1 -------UUGGGGAAACGGCCGCUGAGUGAG-------------------------------------------- 6 0,2 -------UUGGGGAAACGGCCGCUGAGUGAGu------------------------------------------- 2 0,2 >hsa-mir-2114 MA:13-34;mi:49-69 Normal ccuccaugcuccUAGUCCCUUCCUUGAAGCGGUCggauaaucacaugaCGAGCCUCAAGCAAGGGACUUcaagcuggugg ------------UAGUCCCUUCCUUGAAGCGGUC---------------------------------------------- 2 0,0 >hsa-mir-2115 MA:21-42;mi:58-79 Normal acugucaucccacugcuuccAGCUUCCAUGACUCCUGAUGGAggaaucacaugaauuCAUCAGAAUUCAUGGAGGCUAGaagcaguaugaggaucauuua --------------------AGCUUCCAUGACUCCUGAUGa----------------------------------------------------------- 2 0,-2 --------------------AGCUUCCAUGACUCCUGAUGG----------------------------------------------------------- 4 0,-1 --------------------AGCUUCCAUGACUCCUGAUGGA---------------------------------------------------------- 15 0,0 --------------------AGCUUCCAUGACUCCUGAUGGAa--------------------------------------------------------- 5 0,0 --------------------AGCUUCCAUGACUCCUGAUGGAau-------------------------------------------------------- 3 0,0 >hsa-mir-2116 MA:14-34;mi:51-71 Normal gaccuaggcuaggGGUUCUUAGCAUAGGAGGUCUucccaugcuaagaaguCCUCCCAUGCCAAGAACUCCCagacuagga ------------------------------------------------GUCCUCCCAUGCCAAGAACUCC---------- 2 -2,-1 -------------------------------------------------UCCUCCCAUGCCAAGAACUCC---------- 7 -1,-1 >hsa-mir-212 3pM:71-91 Normal cggggcaccccgcccggacagcgcgccggcaccuuggcucuagacugcuuacugcccgggccgcccucagUAACAGUCUCCAGUCACGGCCaccgacgccuggccccgcc ------------------------------ACCUUGGCUCUAGACUGCUUAC---------------------------------------------------------- 2 ------------------------------ACCUUGGCUCUAGACUGCUUACU--------------------------------------------------------- 56 ------------------------------ACCUUGGCUCUAGACUGCUUACUG-------------------------------------------------------- 3 ------------------------------ACCUUGGCUCUAGACUGCUUACUGu------------------------------------------------------- 2 ----------------------------------------------------------------------UAACAGUCUCCAGUCACGGC-------------------- 2 0,-1 ----------------------------------------------------------------------UAACAGUCUCCAGUCACGGCa------------------- 3 0,-1 ----------------------------------------------------------------------UAACAGUCUCCAGUCACGGCC------------------- 4 0,0 ----------------------------------------------------------------------UAACAGUCUCCAGUCACGGCCA------------------ 7 0,1 ----------------------------------------------------------------------UAACAGUCUCCAGUCACGGCCAa----------------- 2 0,1 ----------------------------------------------------------------------UAACAGUCUCCAGUCACGGCCAu----------------- 2 0,1 ----------------------------------------------------------------------UAACAGUCUCCAGUCACGGCCAuu---------------- 2 0,1 >hsa-mir-214 mi:30-51;MA:71-92 Normal ggccuggcuggacagaguugucaugugucUGCCUGUCUACACUUGCUGUGCagaacauccgcucaccuguACAGCAGGCACAGACAGGCAGUcacaugacaacccagccu -----------------------------UGCCUGUCUACACUUGCUGa------------------------------------------------------------- 2 0,-3 -----------------------------UGCCUGUCUACACUUGCUGU------------------------------------------------------------- 5 0,-2 -----------------------------UGCCUGUCUACACUUGCUGUG------------------------------------------------------------ 14 0,-1 -----------------------------UGCCUGUCUACACUUGCUGUGa----------------------------------------------------------- 33 0,-1 -----------------------------UGCCUGUCUACACUUGCUGUGu----------------------------------------------------------- 2 0,-1 -----------------------------UGCCUGUCUACACUUGCUGUGC----------------------------------------------------------- 158 0,0 ------------------------------GCCUGUCUACACUUGCUGUGa----------------------------------------------------------- 2 1,-1 ------------------------------GCCUGUCUACACUUGCUGUGC----------------------------------------------------------- 28 1,0 ------------------------------GCCUGUCUACACUUGCUGUGCA---------------------------------------------------------- 2 1,1 --------------------------------------------------------------------GUACAGCAGGCACAGACAGGCAGU------------------ 4 -2,0 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGC--------------------- 3 -1,-3 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAa------------------- 7 -1,-2 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAaa------------------ 2 -1,-2 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAG------------------- 15 -1,-1 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAGa------------------ 18 -1,-1 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAGaa----------------- 3 -1,-1 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAGg------------------ 2 -1,-1 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAGU------------------ 23 -1,0 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAGUu----------------- 3 -1,0 ----------------------------------------------------------------------ACAGCAGGCACAGACAGG---------------------- 8 0,-4 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGC--------------------- 5 0,-3 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCA-------------------- 12 0,-2 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAa------------------- 26 0,-2 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAaa------------------ 15 0,-2 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAau------------------ 5 0,-2 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAu------------------- 2 0,-2 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAG------------------- 101 0,-1 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGa------------------ 86 0,-1 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGaa----------------- 44 0,-1 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGg------------------ 6 0,-1 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGU------------------ 181 0,0 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGUa----------------- 19 0,0 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGUaa---------------- 11 0,0 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGUau---------------- 9 0,0 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGUu----------------- 9 0,0 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGUuu---------------- 3 0,0 -----------------------------------------------------------------------CAGCAGGCACAGACAGGCAau------------------ 2 1,-2 -----------------------------------------------------------------------CAGCAGGCACAGACAGGCAGa------------------ 2 1,-1 -----------------------------------------------------------------------CAGCAGGCACAGACAGGCAGU------------------ 6 1,0 >hsa-mir-215 5pM:27-47 Normal aucauucagaaaugguauacaggaaaAUGACCUAUGAAUUGACAGACaauauagcugaguuugucugucauuucuuuaggccaauauucuguaugacugugcuacuucaa --------------------------AUGACCUAUGAAUUGACAGAC--------------------------------------------------------------- 22 0,0 --------------------------AUGACCUAUGAAUUGACAGACA-------------------------------------------------------------- 36 0,1 >hsa-mir-216a 5pM:19-40 Normal gauggcugugaguuggcuUAAUCUCAGCUGGCAACUGUGAgauguucauacaaucccucacaguggucucugggauuaugcuaaacagagcaauuuccuagcccucacga ------------------UAAUCUCAGCUGGCAACUGUGA---------------------------------------------------------------------- 2 0,0 >hsa-mir-216b 5pM:11-32 Normal gcagacuggaAAAUCUCUGCAGGCAAAUGUGAugucacugaggaaaucacacacuuacccguagagauucuacagucugaca ----------AAAUCUCUGCAGGCAAAUGUGA-------------------------------------------------- 3 0,0 >hsa-mir-218-1 MA:25-45;mi:68-89 Normal gugauaauguagcgagauuuucugUUGUGCUUGAUCUAACCAUGUgguugcgagguaugaguaaaacAUGGUUCCGUCAAGCACCAUGGaacgucacgcagcuuucuaca ------------------------UUGUGCUUGAUCUAACCAU------------------------------------------------------------------- 2 0,-2 ------------------------UUGUGCUUGAUCUAACCAUG------------------------------------------------------------------ 13 0,-1 ------------------------UUGUGCUUGAUCUAACCAUGa----------------------------------------------------------------- 2 0,-1 ------------------------UUGUGCUUGAUCUAACCAUGU----------------------------------------------------------------- 582 0,0 ------------------------UUGUGCUUGAUCUAACCAUGUG---------------------------------------------------------------- 124 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGa--------------------------------------------------------------- 101 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGaa-------------------------------------------------------------- 2 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGu--------------------------------------------------------------- 81 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGG--------------------------------------------------------------- 16 0,2 ------------------------UUGUGCUUGAUCUAACCAUGUGGU-------------------------------------------------------------- 40 0,3 ------------------------UUGUGCUUGAUCUAACCAUGUGGUU------------------------------------------------------------- 7 0,4 -------------------------UGUGCUUGAUCUAACCAUGU----------------------------------------------------------------- 10 1,0 -------------------------UGUGCUUGAUCUAACCAUGUGGUU------------------------------------------------------------- 2 1,4 >hsa-mir-218-2 MA:25-45;mi:67-88 Normal gaccagucgcugcggggcuuuccuUUGUGCUUGAUCUAACCAUGUgguggaacgauggaaacggaaCAUGGUUCUGUCAAGCACCGCGgaaagcaccgugcucuccugca ------------------------UUGUGCUUGAUCUAACCAU------------------------------------------------------------------- 2 0,-2 ------------------------UUGUGCUUGAUCUAACCAUG------------------------------------------------------------------ 13 0,-1 ------------------------UUGUGCUUGAUCUAACCAUGa----------------------------------------------------------------- 2 0,-1 ------------------------UUGUGCUUGAUCUAACCAUGU----------------------------------------------------------------- 582 0,0 ------------------------UUGUGCUUGAUCUAACCAUGUG---------------------------------------------------------------- 124 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGa--------------------------------------------------------------- 101 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGaa-------------------------------------------------------------- 2 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGu--------------------------------------------------------------- 81 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGG--------------------------------------------------------------- 16 0,2 ------------------------UUGUGCUUGAUCUAACCAUGUGGU-------------------------------------------------------------- 40 0,3 -------------------------UGUGCUUGAUCUAACCAUGU----------------------------------------------------------------- 10 1,0 ------------------------------------------------------------------CAUGGUUCUGUCAAGCACCGCGu--------------------- 2 0,0 >hsa-mir-219-1 5p:21-41;3p:62-83 Normal ccgccccgggccgcggcuccUGAUUGUCCAAACGCAAUUCUcgagucuauggcuccggccgAGAGUUGAGUCUGGACGUCCCGagccgccgcccccaaaccucgagcggg --------------------UGAUUGUCCAAACGCAAUUCUCG------------------------------------------------------------------- 26 0,2 -------------------------------------------------------------AGAGUUGAGUCUGGACGUCCCGu-------------------------- 3 0,0 >hsa-mir-22 mi:15-36;MA:53-74 Normal ggcugagccgcaguAGUUCUUCAGUGGCAAGCUUUAuguccugacccagcuaAAGCUGCCAGUUGAAGAACUGUugcccucugcc --------------AGUUCUUCAGUGGCAAGCU---------------------------------------------------- 2 0,-3 --------------AGUUCUUCAGUGGCAAGCUU--------------------------------------------------- 17 0,-2 --------------AGUUCUUCAGUGGCAAGCUUU-------------------------------------------------- 222 0,-1 --------------AGUUCUUCAGUGGCAAGCUUUu------------------------------------------------- 7 0,-1 --------------AGUUCUUCAGUGGCAAGCUUUA------------------------------------------------- 75 0,0 --------------AGUUCUUCAGUGGCAAGCUUUAa------------------------------------------------ 12 0,0 --------------AGUUCUUCAGUGGCAAGCUUUAU------------------------------------------------ 2 0,1 ---------------GUUCUUCAGUGGCAAGCUUU-------------------------------------------------- 2 1,-1 ---------------------------------------------------AAAGCUGCCAGUUGAAGAACUGU----------- 18 -1,0 ----------------------------------------------------AAGCUGCCAGUUGAAGAA--------------- 775 0,-4 ----------------------------------------------------AAGCUGCCAGUUGAAGAAa-------------- 176 0,-4 ----------------------------------------------------AAGCUGCCAGUUGAAGAAaa------------- 30 0,-4 ----------------------------------------------------AAGCUGCCAGUUGAAGAAau------------- 3 0,-4 ----------------------------------------------------AAGCUGCCAGUUGAAGAAg-------------- 2 0,-4 ----------------------------------------------------AAGCUGCCAGUUGAAGAAu-------------- 4 0,-4 ----------------------------------------------------AAGCUGCCAGUUGAAGAAuu------------- 5 0,-4 ----------------------------------------------------AAGCUGCCAGUUGAAGAAC-------------- 1000 0,-3 ----------------------------------------------------AAGCUGCCAGUUGAAGAACa------------- 21 0,-3 ----------------------------------------------------AAGCUGCCAGUUGAAGAACc------------- 4 0,-3 ----------------------------------------------------AAGCUGCCAGUUGAAGAACg------------- 2 0,-3 ----------------------------------------------------AAGCUGCCAGUUGAAGAACU------------- 3121 0,-2 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUa------------ 41 0,-2 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUaa----------- 7 0,-2 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUau----------- 364 0,-2 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUu------------ 83 0,-2 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUuu----------- 275 0,-2 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUG------------ 6355 0,-1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGa----------- 1686 0,-1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGaa---------- 73 0,-1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGau---------- 18 0,-1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGc----------- 902 0,-1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGg----------- 325 0,-1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGU----------- 168179 0,0 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUa---------- 1738 0,0 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUaa--------- 108 0,0 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUau--------- 62 0,0 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUc---------- 20 0,0 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUg---------- 35 0,0 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUU---------- 2636 0,1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUUa--------- 4 0,1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUUu--------- 80 0,1 -----------------------------------------------------AGCUGCCAGUUGAAGAAC-------------- 22 1,-3 -----------------------------------------------------AGCUGCCAGUUGAAGAACU------------- 81 1,-2 -----------------------------------------------------AGCUGCCAGUUGAAGAACUau----------- 9 1,-2 -----------------------------------------------------AGCUGCCAGUUGAAGAACUu------------ 2 1,-2 -----------------------------------------------------AGCUGCCAGUUGAAGAACUuu----------- 3 1,-2 -----------------------------------------------------AGCUGCCAGUUGAAGAACUG------------ 183 1,-1 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGa----------- 43 1,-1 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGc----------- 26 1,-1 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGg----------- 3 1,-1 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGU----------- 4947 1,0 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGUa---------- 55 1,0 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGUaa--------- 5 1,0 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGUau--------- 2 1,0 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGUU---------- 93 1,1 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGUUa--------- 3 1,1 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGUUu--------- 7 1,1 ------------------------------------------------------GCUGCCAGUUGAAGAACUGU----------- 66 2,0 ------------------------------------------------------GCUGCCAGUUGAAGAACUGUUu--------- 4 2,1 >hsa-mir-221 mi:25-46;MA:65-87 Normal ugaacauccaggucuggggcaugaACCUGGCAUACAAUGUAGAUUUcuguguucguuaggcaacAGCUACAUUGUCUGCUGGGUUUCaggcuaccuggaaacauguucuc -----------------------AACCUGGCAUACAAUGUAGAUU----------------------------------------------------------------- 2 -1,-1 ------------------------ACCUGGCAUACAAUGUAGAUU----------------------------------------------------------------- 8 0,-1 ------------------------ACCUGGCAUACAAUGUAGAUUU---------------------------------------------------------------- 12 0,0 ------------------------ACCUGGCAUACAAUGUAGAUUUC--------------------------------------------------------------- 14 0,1 ------------------------ACCUGGCAUACAAUGUAGAUUUCUG------------------------------------------------------------- 6 0,3 ---------------------------------------------------------------CAGCUACAUUGUCUGCUGGGU-------------------------- 2 -1,-3 ---------------------------------------------------------------CAGCUACAUUGUCUGCUGGGUU------------------------- 6 -1,-2 ---------------------------------------------------------------CAGCUACAUUGUCUGCUGGGUUU------------------------ 20 -1,-1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGG---------------------------- 44 0,-5 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGa--------------------------- 2 0,-5 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGaa-------------------------- 3 0,-5 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGu--------------------------- 2 0,-5 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGuu-------------------------- 4 0,-5 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGG--------------------------- 137 0,-4 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGa-------------------------- 31 0,-4 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGau------------------------- 5 0,-4 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGg-------------------------- 5 0,-4 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGU-------------------------- 514 0,-3 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUa------------------------- 6 0,-3 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUaa------------------------ 27 0,-3 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUau------------------------ 12 0,-3 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUU------------------------- 965 0,-2 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUa------------------------ 88 0,-2 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUaa----------------------- 37 0,-2 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUau----------------------- 55 0,-2 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUc------------------------ 27 0,-2 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUg------------------------ 5 0,-2 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUU------------------------ 4769 0,-1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUa----------------------- 122 0,-1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUaa---------------------- 9 0,-1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUau---------------------- 4 0,-1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUg----------------------- 10 0,-1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUu----------------------- 814 0,-1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUuu---------------------- 30 0,-1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUC----------------------- 1981 0,0 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUCg---------------------- 6 0,0 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUCu---------------------- 135 0,0 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUCA---------------------- 70 0,1 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGU-------------------------- 19 1,-3 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUU------------------------- 37 1,-2 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUU------------------------ 213 1,-1 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUUa----------------------- 2 1,-1 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUUu----------------------- 49 1,-1 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUUC----------------------- 78 1,0 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUUCu---------------------- 6 1,0 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUUCA---------------------- 3 1,1 ------------------------------------------------------------------CUACAUUGUCUGCUGGGUUU------------------------ 3 2,-1 >hsa-mir-222 mi:31-52;MA:69-89 Normal gcugcuggaagguguagguacccucaauggCUCAGUAGCCAGUGUAGAUCCUgucuuucguaaucagcAGCUACAUCUGGCUACUGGGUcucugauggcaucuucuagcu ----------------------------GGCUCAGUAGCCAGUGUAGA-------------------------------------------------------------- 4 -2,-4 ----------------------------GGCUCAGUAGCCAGUGUAGAU------------------------------------------------------------- 2 -2,-3 ----------------------------GGCUCAGUAGCCAGUGUAGAUC------------------------------------------------------------ 9 -2,-2 ----------------------------GGCUCAGUAGCCAGUGUAGAUCC----------------------------------------------------------- 5 -2,-1 -------------------------------------------------------------------CAGCUACAUCUGGCUACUGGGa--------------------- 2 -1,-1 --------------------------------------------------------------------AGCUACAUCUGGCUACUG------------------------ 3 0,-3 --------------------------------------------------------------------AGCUACAUCUGGCUACUGG----------------------- 33 0,-2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGa---------------------- 7 0,-2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGaa--------------------- 2 0,-2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGG---------------------- 98 0,-1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGa--------------------- 81 0,-1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGaa-------------------- 22 0,-1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGau-------------------- 8 0,-1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGc--------------------- 2 0,-1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGg--------------------- 2 0,-1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGU--------------------- 793 0,0 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUa-------------------- 35 0,0 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUaa------------------- 32 0,0 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUau------------------- 17 0,0 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUu-------------------- 23 0,0 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUuu------------------- 5 0,0 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUC-------------------- 393 0,1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCa------------------- 90 0,1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCaa------------------ 2 0,1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCau------------------ 2 0,1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCc------------------- 2 0,1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCg------------------- 13 0,1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCU------------------- 889 0,2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUu------------------ 87 0,2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUuu----------------- 17 0,2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUC------------------ 579 0,3 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUCa----------------- 24 0,3 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUCc----------------- 6 0,3 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUCU----------------- 264 0,4 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGU--------------------- 14 1,0 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUa-------------------- 2 1,0 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUu-------------------- 2 1,0 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUC-------------------- 11 1,1 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUCU------------------- 33 1,2 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUCUu------------------ 4 1,2 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUCUC------------------ 24 1,3 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUCUCU----------------- 4 1,4 >hsa-mir-223 mi:26-47;MA:68-89 Normal ccuggccuccugcagugccacgcucCGUGUAUUUGACAAGCUGAGUUggacacuccaugugguagagUGUCAGUUUGUCAAAUACCCCAagugcggcacaugcuuaccag -------------------------CGUGUAUUUGACAAGCUGAGUUGG------------------------------------------------------------- 2 0,2 -------------------------------------------------------------------UGUCAGUUUGUCAAAUAC------------------------- 6 0,-4 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACC------------------------ 26 0,-3 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCa----------------------- 3 0,-3 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCC----------------------- 18 0,-2 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCC---------------------- 57 0,-1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCu--------------------- 4 0,-1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCA--------------------- 337 0,0 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAg-------------------- 8 0,0 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAu-------------------- 57 0,0 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAuu------------------- 4 0,0 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAA-------------------- 186 0,1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAAa------------------- 13 0,1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAAaa------------------ 2 0,1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAAu------------------- 37 0,1 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCCC---------------------- 4 1,-1 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCCCA--------------------- 25 1,0 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCCCAu-------------------- 3 1,0 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCCCAA-------------------- 34 1,1 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCCCAAu------------------- 2 1,1 >hsa-mir-224 MA:8-28;mi:53-75 Normal gggcuuuCAAGUCACUAGUGGUUCCGUUuaguagaugauugugcauuguuucAAAAUGGUGCCCUAGUGACUACAaagccc -------CAAGUCACUAGUGGUUCC-------------------------------------------------------- 2 0,-3 -------CAAGUCACUAGUGGUUCCGUU----------------------------------------------------- 17 0,0 -------CAAGUCACUAGUGGUUCCGUUU---------------------------------------------------- 600 0,1 -------CAAGUCACUAGUGGUUCCGUUUu--------------------------------------------------- 20 0,1 -------CAAGUCACUAGUGGUUCCGUUUA--------------------------------------------------- 28 0,2 -------CAAGUCACUAGUGGUUCCGUUUAu-------------------------------------------------- 5 0,2 -------CAAGUCACUAGUGGUUCCGUUUAG-------------------------------------------------- 126 0,3 -------CAAGUCACUAGUGGUUCCGUUUAGa------------------------------------------------- 2 0,3 -------CAAGUCACUAGUGGUUCCGUUUAGU------------------------------------------------- 8 0,4 --------AAGUCACUAGUGGUUCCGUUU---------------------------------------------------- 7 1,1 ----------------------------------------------------AAAAUGGUGCCCUAGUGACUACA------ 2 0,0 -----------------------------------------------------AAAUGGUGCCCUAGUGACU--------- 17 1,-3 -----------------------------------------------------AAAUGGUGCCCUAGUGACUAa------- 2 1,-2 -----------------------------------------------------AAAUGGUGCCCUAGUGACUAaa------ 2 1,-2 -----------------------------------------------------AAAUGGUGCCCUAGUGACUAu------- 5 1,-2 -----------------------------------------------------AAAUGGUGCCCUAGUGACUAuu------ 2 1,-2 -----------------------------------------------------AAAUGGUGCCCUAGUGACUAC------- 28 1,-1 -----------------------------------------------------AAAUGGUGCCCUAGUGACUACu------ 6 1,-1 -----------------------------------------------------AAAUGGUGCCCUAGUGACUACA------ 89 1,0 -----------------------------------------------------AAAUGGUGCCCUAGUGACUACAu----- 2 1,0 -----------------------------------------------------AAAUGGUGCCCUAGUGACUACAA----- 5 1,1 ------------------------------------------------------AAUGGUGCCCUAGUGACUACA------ 6 2,0 ------------------------------------------------------AAUGGUGCCCUAGUGACUACAA----- 2 2,1 >hsa-mir-2277 5p:18-41;3p:59-79 Normal gugcuuccugcgggcugAGCGCGGGCUGAGCGCUGCCAGUCagcgcucacauuaaggcUGACAGCGCCCUGCCUGGCUCggccggcgaagcuc -----------------AGCGCGGGCUGAGCGCUGCCAGU----------------------------------------------------- 4 0,-1 -----------------AGCGCGGGCUGAGCGCUGCCAGUC---------------------------------------------------- 3 0,0 ----------------------------------------------------------UGACAGCGCCCUGCCUGGCUCG------------- 3 0,1 >hsa-mir-2355 5p:11-31;3p:54-75 Normal cagacgugucAUCCCCAGAUACAAUGGACAAuaugcuauuauaaucguauggcAUUGUCCUUGCUGUUUGGAGAUaauacugcugac ----------AUCCCCAGAUACAAUGGACA--------------------------------------------------------- 5 0,-1 ----------AUCCCCAGAUACAAUGGACAAU------------------------------------------------------- 4 0,1 -----------------------------------------------------AUUGUCCUUGCUGUUUGGAGAU------------ 2 0,0 >hsa-mir-23a mi:9-30;MA:45-65 Normal ggccggcuGGGGUUCCUGGGGAUGGGAUUUgcuuccugucacaaAUCACAUUGCCAGGGAUUUCCaaccgacc --------GGGGUUCCUGGGGAUGGGA---------------------------------------------- 2 0,-3 --------GGGGUUCCUGGGGAUGGGAU--------------------------------------------- 4 0,-2 --------GGGGUUCCUGGGGAUGGGAUU-------------------------------------------- 21 0,-1 --------GGGGUUCCUGGGGAUGGGAUUU------------------------------------------- 30 0,0 -------------------------------------------AAUCACAUUGCCAGGGAUU----------- 17 -1,-3 -------------------------------------------AAUCACAUUGCCAGGGAUUU---------- 30 -1,-2 -------------------------------------------AAUCACAUUGCCAGGGAUUUa--------- 2 -1,-2 -------------------------------------------AAUCACAUUGCCAGGGAUUUaa-------- 2 -1,-2 -------------------------------------------AAUCACAUUGCCAGGGAUUUC--------- 18 -1,-1 -------------------------------------------AAUCACAUUGCCAGGGAUUUCC-------- 50 -1,0 -------------------------------------------AAUCACAUUGCCAGGGAUUUCCA------- 25 -1,1 --------------------------------------------AUCACAUUGCCAGGGAUU----------- 600 0,-3 --------------------------------------------AUCACAUUGCCAGGGAUUU---------- 1755 0,-2 --------------------------------------------AUCACAUUGCCAGGGAUUUa--------- 113 0,-2 --------------------------------------------AUCACAUUGCCAGGGAUUUaa-------- 138 0,-2 --------------------------------------------AUCACAUUGCCAGGGAUUUau-------- 3 0,-2 --------------------------------------------AUCACAUUGCCAGGGAUUUg--------- 9 0,-2 --------------------------------------------AUCACAUUGCCAGGGAUUUu--------- 190 0,-2 --------------------------------------------AUCACAUUGCCAGGGAUUUuu-------- 2 0,-2 --------------------------------------------AUCACAUUGCCAGGGAUUUC--------- 2896 0,-1 --------------------------------------------AUCACAUUGCCAGGGAUUUCa-------- 581 0,-1 --------------------------------------------AUCACAUUGCCAGGGAUUUCaa------- 45 0,-1 --------------------------------------------AUCACAUUGCCAGGGAUUUCau------- 3 0,-1 --------------------------------------------AUCACAUUGCCAGGGAUUUCg-------- 16 0,-1 --------------------------------------------AUCACAUUGCCAGGGAUUUCu-------- 101 0,-1 --------------------------------------------AUCACAUUGCCAGGGAUUUCC-------- 7418 0,0 --------------------------------------------AUCACAUUGCCAGGGAUUUCCc------- 7 0,0 --------------------------------------------AUCACAUUGCCAGGGAUUUCCg------- 16 0,0 --------------------------------------------AUCACAUUGCCAGGGAUUUCCu------- 78 0,0 --------------------------------------------AUCACAUUGCCAGGGAUUUCCuu------ 14 0,0 --------------------------------------------AUCACAUUGCCAGGGAUUUCCA------- 9164 0,1 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAc------ 7 0,1 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAg------ 30 0,1 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAu------ 612 0,1 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAuu----- 19 0,1 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAA------ 1108 0,2 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAAa----- 28 0,2 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAAaa---- 2 0,2 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAAu----- 193 0,2 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAAC----- 8 0,3 ---------------------------------------------UCACAUUGCCAGGGAUUUC--------- 11 1,-1 ---------------------------------------------UCACAUUGCCAGGGAUUUCa-------- 6 1,-1 ---------------------------------------------UCACAUUGCCAGGGAUUUCC-------- 29 1,0 ---------------------------------------------UCACAUUGCCAGGGAUUUCCA------- 29 1,1 ---------------------------------------------UCACAUUGCCAGGGAUUUCCAu------ 2 1,1 ---------------------------------------------UCACAUUGCCAGGGAUUUCCAA------ 13 1,2 ---------------------------------------------UCACAUUGCCAGGGAUUUCCAAa----- 3 1,2 ---------------------------------------------UCACAUUGCCAGGGAUUUCCAAu----- 4 1,2 ---------------------------------------------UCACAUUGCCAGGGAUUUCCAAC----- 10 1,3 ----------------------------------------------CACAUUGCCAGGGAUUUC--------- 3 2,-1 ----------------------------------------------CACAUUGCCAGGGAUUUCC-------- 2 2,0 ----------------------------------------------CACAUUGCCAGGGAUUUCCA------- 8 2,1 >hsa-mir-23b mi:20-41;MA:58-78 Normal cucaggugcucuggcugcuUGGGUUCCUGGCAUGCUGAUUUgugacuuaagauuaaaAUCACAUUGCCAGGGAUUACCacgcaaccacgaccuuggc -------------------UGGGUUCCUGGCAUGCUGA----------------------------------------------------------- 2 0,-3 -------------------UGGGUUCCUGGCAUGCUGAUUU-------------------------------------------------------- 6 0,0 --------------------------------------------------------AAUCACAUUGCCAGGGAUU---------------------- 17 -1,-3 --------------------------------------------------------AAUCACAUUGCCAGGGAUUACC------------------- 5 -1,0 ---------------------------------------------------------AUCACAUUGCCAGGGAUU---------------------- 600 0,-3 ---------------------------------------------------------AUCACAUUGCCAGGGAUUA--------------------- 123 0,-2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUAa-------------------- 71 0,-2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUAaa------------------- 56 0,-2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUAg-------------------- 2 0,-2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUAu-------------------- 25 0,-2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUAC-------------------- 323 0,-1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACa------------------- 126 0,-1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACaa------------------ 17 0,-1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACu------------------- 12 0,-1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACC------------------- 1220 0,0 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCu------------------ 2 0,0 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCA------------------ 1437 0,1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCAa----------------- 26 0,1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCAg----------------- 2 0,1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCAu----------------- 138 0,1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCAuu---------------- 26 0,1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCAC----------------- 408 0,2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCACa---------------- 29 0,2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCACc---------------- 9 0,2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCACu---------------- 460 0,2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCACuu--------------- 2 0,2 ----------------------------------------------------------UCACAUUGCCAGGGAUUAa-------------------- 2 1,-2 ----------------------------------------------------------UCACAUUGCCAGGGAUUAC-------------------- 4 1,-1 ----------------------------------------------------------UCACAUUGCCAGGGAUUACC------------------- 9 1,0 ----------------------------------------------------------UCACAUUGCCAGGGAUUACCA------------------ 10 1,1 ----------------------------------------------------------UCACAUUGCCAGGGAUUACCAa----------------- 2 1,1 ----------------------------------------------------------UCACAUUGCCAGGGAUUACCAu----------------- 2 1,1 ----------------------------------------------------------UCACAUUGCCAGGGAUUACCAuu---------------- 4 1,1 ----------------------------------------------------------UCACAUUGCCAGGGAUUACCAC----------------- 3 1,2 ----------------------------------------------------------UCACAUUGCCAGGGAUUACCACu---------------- 23 1,2 >hsa-mir-23c 3pM:66-87 Normal agugacuuuccaggugucacacagugaguggcauaaucagaguacaauuugagucaugcccauacAUCACAUUGCCAGUGAUUACCCaaggaaagugacg -----------------------------------------------------------------AUCACAUUGCCAGUGAUU----------------- 2 0,-4 >hsa-mir-24-1 mi:7-28;MA:44-65 Normal cuccggUGCCUACUGAGCUGAUAUCAGUucucauuuuacacacUGGCUCAGUUCAGCAGGAACAGgag -----GUGCCUACUGAGCUGAUAUCA------------------------------------------ 10 -1,-2 -----GUGCCUACUGAGCUGAUAUCAG----------------------------------------- 4 -1,-1 -----GUGCCUACUGAGCUGAUAUCAGU---------------------------------------- 11 -1,0 -----------------------------------------ACUGGCUCAGUUCAGCAGGAAC----- 5 -2,-2 -----------------------------------------ACUGGCUCAGUUCAGCAGGAACA---- 2 -2,-1 ------------------------------------------CUGGCUCAGUUCAGCAGGAA------ 3 -1,-3 ------------------------------------------CUGGCUCAGUUCAGCAGGAAa----- 4 -1,-3 ------------------------------------------CUGGCUCAGUUCAGCAGGAAC----- 36 -1,-2 ------------------------------------------CUGGCUCAGUUCAGCAGGAACA---- 9 -1,-1 ------------------------------------------CUGGCUCAGUUCAGCAGGAACAa--- 3 -1,-1 ------------------------------------------CUGGCUCAGUUCAGCAGGAACAG--- 28 -1,0 ------------------------------------------CUGGCUCAGUUCAGCAGGAACAGa-- 22 -1,0 ------------------------------------------CUGGCUCAGUUCAGCAGGAACAGu-- 76 -1,0 ------------------------------------------CUGGCUCAGUUCAGCAGGAACAGuu- 3 -1,0 -------------------------------------------UGGCUCAGUUCAGCAGGA------- 474 0,-4 -------------------------------------------UGGCUCAGUUCAGCAGGAc------ 6 0,-4 -------------------------------------------UGGCUCAGUUCAGCAGGAg------ 18 0,-4 -------------------------------------------UGGCUCAGUUCAGCAGGAu------ 51 0,-4 -------------------------------------------UGGCUCAGUUCAGCAGGAuu----- 8 0,-4 -------------------------------------------UGGCUCAGUUCAGCAGGAA------ 1267 0,-3 -------------------------------------------UGGCUCAGUUCAGCAGGAAa----- 1634 0,-3 -------------------------------------------UGGCUCAGUUCAGCAGGAAaa---- 194 0,-3 -------------------------------------------UGGCUCAGUUCAGCAGGAAau---- 64 0,-3 -------------------------------------------UGGCUCAGUUCAGCAGGAAg----- 91 0,-3 -------------------------------------------UGGCUCAGUUCAGCAGGAAu----- 479 0,-3 -------------------------------------------UGGCUCAGUUCAGCAGGAAuu---- 2 0,-3 -------------------------------------------UGGCUCAGUUCAGCAGGAAC----- 8590 0,-2 -------------------------------------------UGGCUCAGUUCAGCAGGAACc---- 2 0,-2 -------------------------------------------UGGCUCAGUUCAGCAGGAACg---- 17 0,-2 -------------------------------------------UGGCUCAGUUCAGCAGGAACu---- 69 0,-2 -------------------------------------------UGGCUCAGUUCAGCAGGAACuu--- 2 0,-2 -------------------------------------------UGGCUCAGUUCAGCAGGAACA---- 1669 0,-1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAa--- 481 0,-1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAaa-- 105 0,-1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAau-- 60 0,-1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAc--- 21 0,-1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAu--- 64 0,-1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAuu-- 8 0,-1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAG--- 6661 0,0 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGa-- 4013 0,0 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGaa- 103 0,0 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGau- 35 0,0 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGc-- 85 0,0 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGu-- 14994 0,0 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGuu- 279 0,0 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGG-- 69 0,1 --------------------------------------------GGCUCAGUUCAGCAGGAA------ 43 1,-3 --------------------------------------------GGCUCAGUUCAGCAGGAAa----- 57 1,-3 --------------------------------------------GGCUCAGUUCAGCAGGAAaa---- 6 1,-3 --------------------------------------------GGCUCAGUUCAGCAGGAAau---- 3 1,-3 --------------------------------------------GGCUCAGUUCAGCAGGAAg----- 4 1,-3 --------------------------------------------GGCUCAGUUCAGCAGGAAu----- 21 1,-3 --------------------------------------------GGCUCAGUUCAGCAGGAAC----- 324 1,-2 --------------------------------------------GGCUCAGUUCAGCAGGAACu---- 2 1,-2 --------------------------------------------GGCUCAGUUCAGCAGGAACA---- 74 1,-1 --------------------------------------------GGCUCAGUUCAGCAGGAACAa--- 19 1,-1 --------------------------------------------GGCUCAGUUCAGCAGGAACAG--- 271 1,0 --------------------------------------------GGCUCAGUUCAGCAGGAACAGa-- 178 1,0 --------------------------------------------GGCUCAGUUCAGCAGGAACAGaa- 4 1,0 --------------------------------------------GGCUCAGUUCAGCAGGAACAGc-- 3 1,0 --------------------------------------------GGCUCAGUUCAGCAGGAACAGu-- 627 1,0 --------------------------------------------GGCUCAGUUCAGCAGGAACAGuu- 8 1,0 --------------------------------------------GGCUCAGUUCAGCAGGAACAGG-- 2 1,1 ---------------------------------------------GCUCAGUUCAGCAGGAAC----- 2 2,-2 ---------------------------------------------GCUCAGUUCAGCAGGAACAGa-- 4 2,0 ---------------------------------------------GCUCAGUUCAGCAGGAACAGu-- 19 2,0 ---------------------------------------------GCUCAGUUCAGCAGGAACAGuu- 11 2,0 ---------------------------------------------GCUCAGUUCAGCAGGAACAGG-- 5 2,1 ---------------------------------------------GCUCAGUUCAGCAGGAACAGGu- 9 2,1 ---------------------------------------------GCUCAGUUCAGCAGGAACAGGA- 4 2,2 >hsa-mir-24-2 mi:13-34;MA:50-71 Normal cucugccucccgUGCCUACUGAGCUGAAACACAGuugguuuguguacacUGGCUCAGUUCAGCAGGAACAGgg -----------GUGCCUACUGAGCUGAAAC------------------------------------------- 4 -1,-4 -----------GUGCCUACUGAGCUGAAACA------------------------------------------ 33 -1,-3 -----------GUGCCUACUGAGCUGAAACAC----------------------------------------- 152 -1,-2 -----------GUGCCUACUGAGCUGAAACACA---------------------------------------- 150 -1,-1 -----------GUGCCUACUGAGCUGAAACACAG--------------------------------------- 65 -1,0 -----------GUGCCUACUGAGCUGAAACACAGU-------------------------------------- 65 -1,1 ------------UGCCUACUGAGCUGAAACACA---------------------------------------- 2 0,-1 ------------UGCCUACUGAGCUGAAACACAG--------------------------------------- 2 0,0 ------------UGCCUACUGAGCUGAAACACAGU-------------------------------------- 2 0,1 -----------------------------------------------ACUGGCUCAGUUCAGCAGGAAC---- 5 -2,-2 -----------------------------------------------ACUGGCUCAGUUCAGCAGGAACA--- 2 -2,-1 ------------------------------------------------CUGGCUCAGUUCAGCAGGAA----- 3 -1,-3 ------------------------------------------------CUGGCUCAGUUCAGCAGGAAa---- 4 -1,-3 ------------------------------------------------CUGGCUCAGUUCAGCAGGAAC---- 36 -1,-2 ------------------------------------------------CUGGCUCAGUUCAGCAGGAACA--- 9 -1,-1 ------------------------------------------------CUGGCUCAGUUCAGCAGGAACAa-- 3 -1,-1 ------------------------------------------------CUGGCUCAGUUCAGCAGGAACAG-- 28 -1,0 ------------------------------------------------CUGGCUCAGUUCAGCAGGAACAGa- 22 -1,0 ------------------------------------------------CUGGCUCAGUUCAGCAGGAACAGu- 76 -1,0 ------------------------------------------------CUGGCUCAGUUCAGCAGGAACAGuu 3 -1,0 -------------------------------------------------UGGCUCAGUUCAGCAGGA------ 474 0,-4 -------------------------------------------------UGGCUCAGUUCAGCAGGAc----- 6 0,-4 -------------------------------------------------UGGCUCAGUUCAGCAGGAg----- 18 0,-4 -------------------------------------------------UGGCUCAGUUCAGCAGGAu----- 51 0,-4 -------------------------------------------------UGGCUCAGUUCAGCAGGAuu---- 8 0,-4 -------------------------------------------------UGGCUCAGUUCAGCAGGAA----- 1267 0,-3 -------------------------------------------------UGGCUCAGUUCAGCAGGAAa---- 1634 0,-3 -------------------------------------------------UGGCUCAGUUCAGCAGGAAaa--- 194 0,-3 -------------------------------------------------UGGCUCAGUUCAGCAGGAAau--- 64 0,-3 -------------------------------------------------UGGCUCAGUUCAGCAGGAAg---- 91 0,-3 -------------------------------------------------UGGCUCAGUUCAGCAGGAAu---- 479 0,-3 -------------------------------------------------UGGCUCAGUUCAGCAGGAAuu--- 2 0,-3 -------------------------------------------------UGGCUCAGUUCAGCAGGAAC---- 8590 0,-2 -------------------------------------------------UGGCUCAGUUCAGCAGGAACc--- 2 0,-2 -------------------------------------------------UGGCUCAGUUCAGCAGGAACg--- 17 0,-2 -------------------------------------------------UGGCUCAGUUCAGCAGGAACu--- 69 0,-2 -------------------------------------------------UGGCUCAGUUCAGCAGGAACuu-- 2 0,-2 -------------------------------------------------UGGCUCAGUUCAGCAGGAACA--- 1669 0,-1 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAa-- 481 0,-1 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAaa- 105 0,-1 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAau- 60 0,-1 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAc-- 21 0,-1 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAu-- 64 0,-1 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAuu- 8 0,-1 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAG-- 6661 0,0 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAGa- 4013 0,0 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAGaa 103 0,0 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAGau 35 0,0 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAGc- 85 0,0 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAGu- 14994 0,0 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAGuu 279 0,0 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAGG- 69 0,1 --------------------------------------------------GGCUCAGUUCAGCAGGAA----- 43 1,-3 --------------------------------------------------GGCUCAGUUCAGCAGGAAa---- 57 1,-3 --------------------------------------------------GGCUCAGUUCAGCAGGAAaa--- 6 1,-3 --------------------------------------------------GGCUCAGUUCAGCAGGAAau--- 3 1,-3 --------------------------------------------------GGCUCAGUUCAGCAGGAAg---- 4 1,-3 --------------------------------------------------GGCUCAGUUCAGCAGGAAu---- 21 1,-3 --------------------------------------------------GGCUCAGUUCAGCAGGAAC---- 324 1,-2 --------------------------------------------------GGCUCAGUUCAGCAGGAACu--- 2 1,-2 --------------------------------------------------GGCUCAGUUCAGCAGGAACA--- 74 1,-1 --------------------------------------------------GGCUCAGUUCAGCAGGAACAa-- 19 1,-1 --------------------------------------------------GGCUCAGUUCAGCAGGAACAG-- 271 1,0 --------------------------------------------------GGCUCAGUUCAGCAGGAACAGa- 178 1,0 --------------------------------------------------GGCUCAGUUCAGCAGGAACAGaa 4 1,0 --------------------------------------------------GGCUCAGUUCAGCAGGAACAGc- 3 1,0 --------------------------------------------------GGCUCAGUUCAGCAGGAACAGu- 627 1,0 --------------------------------------------------GGCUCAGUUCAGCAGGAACAGuu 8 1,0 --------------------------------------------------GGCUCAGUUCAGCAGGAACAGG- 2 1,1 ---------------------------------------------------GCUCAGUUCAGCAGGAAC---- 2 2,-2 ---------------------------------------------------GCUCAGUUCAGCAGGAACAGa- 4 2,0 ---------------------------------------------------GCUCAGUUCAGCAGGAACAGu- 19 2,0 ---------------------------------------------------GCUCAGUUCAGCAGGAACAGuu 11 2,0 ---------------------------------------------------GCUCAGUUCAGCAGGAACAGG- 5 2,1 ---------------------------------------------------GCUCAGUUCAGCAGGAACAGGu 9 2,1 >hsa-mir-25 mi:14-34;MA:52-73 Normal ggccaguguugagAGGCGGAGACUUGGGCAAUUGcuggacgcugcccugggCAUUGCACUUGUCUCGGUCUGAcagugccggcc -------------AGGCGGAGACUUGGGCAAUUGCU------------------------------------------------ 3 0,2 ---------------------------------------------------CAUUGCACUUGUCUCGGU--------------- 24 0,-4 ---------------------------------------------------CAUUGCACUUGUCUCGGUaa------------- 2 0,-4 ---------------------------------------------------CAUUGCACUUGUCUCGGUC-------------- 12 0,-3 ---------------------------------------------------CAUUGCACUUGUCUCGGUCa------------- 6 0,-3 ---------------------------------------------------CAUUGCACUUGUCUCGGUCU------------- 203 0,-2 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUaa----------- 6 0,-2 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUu------------ 7 0,-2 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUG------------ 155 0,-1 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGc----------- 9 0,-1 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGg----------- 6 0,-1 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGu----------- 161 0,-1 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGuu---------- 4 0,-1 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGA----------- 3346 0,0 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGAa---------- 145 0,0 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGAaa--------- 5 0,0 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGAau--------- 4 0,0 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGAg---------- 14 0,0 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGAu---------- 75 0,0 ----------------------------------------------------AUUGCACUUGUCUCGGUCU------------- 4 1,-2 ----------------------------------------------------AUUGCACUUGUCUCGGUCUGu----------- 3 1,-1 ----------------------------------------------------AUUGCACUUGUCUCGGUCUGA----------- 130 1,0 ----------------------------------------------------AUUGCACUUGUCUCGGUCUGAa---------- 4 1,0 >hsa-mir-26a-1 MA:10-31;mi:49-70 Normal guggccucgUUCAAGUAAUCCAGGAUAGGCUgugcaggucccaaugggCCUAUUCUUGGUUACUUGCACGgggacgc ---------UUCAAGUAAUCCAGGAUA-------------------------------------------------- 319 0,-4 ---------UUCAAGUAAUCCAGGAUAa------------------------------------------------- 100 0,-4 ---------UUCAAGUAAUCCAGGAUAaa------------------------------------------------ 67 0,-4 ---------UUCAAGUAAUCCAGGAUAc------------------------------------------------- 4 0,-4 ---------UUCAAGUAAUCCAGGAUAu------------------------------------------------- 6 0,-4 ---------UUCAAGUAAUCCAGGAUAG------------------------------------------------- 505 0,-3 ---------UUCAAGUAAUCCAGGAUAGa------------------------------------------------ 184 0,-3 ---------UUCAAGUAAUCCAGGAUAGaa----------------------------------------------- 51 0,-3 ---------UUCAAGUAAUCCAGGAUAGau----------------------------------------------- 3 0,-3 ---------UUCAAGUAAUCCAGGAUAGu------------------------------------------------ 18 0,-3 ---------UUCAAGUAAUCCAGGAUAGG------------------------------------------------ 2730 0,-2 ---------UUCAAGUAAUCCAGGAUAGGa----------------------------------------------- 1001 0,-2 ---------UUCAAGUAAUCCAGGAUAGGaa---------------------------------------------- 766 0,-2 ---------UUCAAGUAAUCCAGGAUAGGau---------------------------------------------- 44 0,-2 ---------UUCAAGUAAUCCAGGAUAGGg----------------------------------------------- 2 0,-2 ---------UUCAAGUAAUCCAGGAUAGGu----------------------------------------------- 87 0,-2 ---------UUCAAGUAAUCCAGGAUAGGuu---------------------------------------------- 40 0,-2 ---------UUCAAGUAAUCCAGGAUAGGC----------------------------------------------- 4664 0,-1 ---------UUCAAGUAAUCCAGGAUAGGCa---------------------------------------------- 1041 0,-1 ---------UUCAAGUAAUCCAGGAUAGGCaa--------------------------------------------- 414 0,-1 ---------UUCAAGUAAUCCAGGAUAGGCau--------------------------------------------- 252 0,-1 ---------UUCAAGUAAUCCAGGAUAGGCc---------------------------------------------- 18 0,-1 ---------UUCAAGUAAUCCAGGAUAGGCg---------------------------------------------- 27 0,-1 ---------UUCAAGUAAUCCAGGAUAGGCU---------------------------------------------- 16334 0,0 ---------UUCAAGUAAUCCAGGAUAGGCUa--------------------------------------------- 866 0,0 ---------UUCAAGUAAUCCAGGAUAGGCUaa-------------------------------------------- 43 0,0 ---------UUCAAGUAAUCCAGGAUAGGCUau-------------------------------------------- 95 0,0 ---------UUCAAGUAAUCCAGGAUAGGCUc--------------------------------------------- 2 0,0 ---------UUCAAGUAAUCCAGGAUAGGCUu--------------------------------------------- 1866 0,0 ---------UUCAAGUAAUCCAGGAUAGGCUuu-------------------------------------------- 171 0,0 ---------UUCAAGUAAUCCAGGAUAGGCUG--------------------------------------------- 107 0,1 ---------UUCAAGUAAUCCAGGAUAGGCUGa-------------------------------------------- 2 0,1 ---------UUCAAGUAAUCCAGGAUAGGCUGU-------------------------------------------- 17 0,2 ----------UCAAGUAAUCCAGGAUAG------------------------------------------------- 11 1,-3 ----------UCAAGUAAUCCAGGAUAGa------------------------------------------------ 2 1,-3 ----------UCAAGUAAUCCAGGAUAGaa----------------------------------------------- 2 1,-3 ----------UCAAGUAAUCCAGGAUAGG------------------------------------------------ 42 1,-2 ----------UCAAGUAAUCCAGGAUAGGa----------------------------------------------- 18 1,-2 ----------UCAAGUAAUCCAGGAUAGGaa---------------------------------------------- 11 1,-2 ----------UCAAGUAAUCCAGGAUAGGC----------------------------------------------- 99 1,-1 ----------UCAAGUAAUCCAGGAUAGGCa---------------------------------------------- 38 1,-1 ----------UCAAGUAAUCCAGGAUAGGCaa--------------------------------------------- 7 1,-1 ----------UCAAGUAAUCCAGGAUAGGCau--------------------------------------------- 4 1,-1 ----------UCAAGUAAUCCAGGAUAGGCU---------------------------------------------- 364 1,0 ----------UCAAGUAAUCCAGGAUAGGCUa--------------------------------------------- 21 1,0 ----------UCAAGUAAUCCAGGAUAGGCUau-------------------------------------------- 4 1,0 ----------UCAAGUAAUCCAGGAUAGGCUu--------------------------------------------- 37 1,0 -----------CAAGUAAUCCAGGAUAGGaa---------------------------------------------- 2 2,-2 -----------CAAGUAAUCCAGGAUAGGCU---------------------------------------------- 15 2,0 -----------CAAGUAAUCCAGGAUAGGCUau-------------------------------------------- 2 2,0 -----------CAAGUAAUCCAGGAUAGGCUu--------------------------------------------- 4 2,0 ------------------------------------------------CCUAUUCUUGGUUACUUGCACG------- 2 0,0 >hsa-mir-26a-2 MA:14-35;mi:52-73 Normal ggcuguggcuggaUUCAAGUAAUCCAGGAUAGGCUguuuccaucugugaggCCUAUUCUUGAUUACUUGUUUCuggaggcagcu ------------AUUCAAGUAAUCCAGGAUAGG--------------------------------------------------- 2 -1,-2 -------------UUCAAGUAAUCCAGGAUA----------------------------------------------------- 319 0,-4 -------------UUCAAGUAAUCCAGGAUAa---------------------------------------------------- 100 0,-4 -------------UUCAAGUAAUCCAGGAUAaa--------------------------------------------------- 67 0,-4 -------------UUCAAGUAAUCCAGGAUAc---------------------------------------------------- 4 0,-4 -------------UUCAAGUAAUCCAGGAUAu---------------------------------------------------- 6 0,-4 -------------UUCAAGUAAUCCAGGAUAG---------------------------------------------------- 505 0,-3 -------------UUCAAGUAAUCCAGGAUAGa--------------------------------------------------- 184 0,-3 -------------UUCAAGUAAUCCAGGAUAGaa-------------------------------------------------- 51 0,-3 -------------UUCAAGUAAUCCAGGAUAGau-------------------------------------------------- 3 0,-3 -------------UUCAAGUAAUCCAGGAUAGu--------------------------------------------------- 18 0,-3 -------------UUCAAGUAAUCCAGGAUAGG--------------------------------------------------- 2730 0,-2 -------------UUCAAGUAAUCCAGGAUAGGa-------------------------------------------------- 1001 0,-2 -------------UUCAAGUAAUCCAGGAUAGGaa------------------------------------------------- 766 0,-2 -------------UUCAAGUAAUCCAGGAUAGGau------------------------------------------------- 44 0,-2 -------------UUCAAGUAAUCCAGGAUAGGg-------------------------------------------------- 2 0,-2 -------------UUCAAGUAAUCCAGGAUAGGu-------------------------------------------------- 87 0,-2 -------------UUCAAGUAAUCCAGGAUAGGuu------------------------------------------------- 40 0,-2 -------------UUCAAGUAAUCCAGGAUAGGC-------------------------------------------------- 4664 0,-1 -------------UUCAAGUAAUCCAGGAUAGGCa------------------------------------------------- 1041 0,-1 -------------UUCAAGUAAUCCAGGAUAGGCaa------------------------------------------------ 414 0,-1 -------------UUCAAGUAAUCCAGGAUAGGCau------------------------------------------------ 252 0,-1 -------------UUCAAGUAAUCCAGGAUAGGCc------------------------------------------------- 18 0,-1 -------------UUCAAGUAAUCCAGGAUAGGCg------------------------------------------------- 27 0,-1 -------------UUCAAGUAAUCCAGGAUAGGCU------------------------------------------------- 16334 0,0 -------------UUCAAGUAAUCCAGGAUAGGCUa------------------------------------------------ 866 0,0 -------------UUCAAGUAAUCCAGGAUAGGCUaa----------------------------------------------- 43 0,0 -------------UUCAAGUAAUCCAGGAUAGGCUau----------------------------------------------- 95 0,0 -------------UUCAAGUAAUCCAGGAUAGGCUc------------------------------------------------ 2 0,0 -------------UUCAAGUAAUCCAGGAUAGGCUu------------------------------------------------ 1866 0,0 -------------UUCAAGUAAUCCAGGAUAGGCUuu----------------------------------------------- 171 0,0 -------------UUCAAGUAAUCCAGGAUAGGCUG------------------------------------------------ 107 0,1 -------------UUCAAGUAAUCCAGGAUAGGCUGa----------------------------------------------- 2 0,1 -------------UUCAAGUAAUCCAGGAUAGGCUGU----------------------------------------------- 17 0,2 --------------UCAAGUAAUCCAGGAUAG---------------------------------------------------- 11 1,-3 --------------UCAAGUAAUCCAGGAUAGa--------------------------------------------------- 2 1,-3 --------------UCAAGUAAUCCAGGAUAGaa-------------------------------------------------- 2 1,-3 --------------UCAAGUAAUCCAGGAUAGG--------------------------------------------------- 42 1,-2 --------------UCAAGUAAUCCAGGAUAGGa-------------------------------------------------- 18 1,-2 --------------UCAAGUAAUCCAGGAUAGGaa------------------------------------------------- 11 1,-2 --------------UCAAGUAAUCCAGGAUAGGC-------------------------------------------------- 99 1,-1 --------------UCAAGUAAUCCAGGAUAGGCa------------------------------------------------- 38 1,-1 --------------UCAAGUAAUCCAGGAUAGGCaa------------------------------------------------ 7 1,-1 --------------UCAAGUAAUCCAGGAUAGGCau------------------------------------------------ 4 1,-1 --------------UCAAGUAAUCCAGGAUAGGCU------------------------------------------------- 364 1,0 --------------UCAAGUAAUCCAGGAUAGGCUa------------------------------------------------ 21 1,0 --------------UCAAGUAAUCCAGGAUAGGCUau----------------------------------------------- 4 1,0 --------------UCAAGUAAUCCAGGAUAGGCUu------------------------------------------------ 37 1,0 ---------------CAAGUAAUCCAGGAUAGGaa------------------------------------------------- 2 2,-2 ---------------CAAGUAAUCCAGGAUAGGCU------------------------------------------------- 15 2,0 ---------------CAAGUAAUCCAGGAUAGGCUau----------------------------------------------- 2 2,0 ---------------CAAGUAAUCCAGGAUAGGCUu------------------------------------------------ 4 2,0 ---------------------------------------------------CCUAUUCUUGAUUACUUGUUU------------ 10 0,-1 ---------------------------------------------------CCUAUUCUUGAUUACUUGUUUC----------- 11 0,0 ----------------------------------------------------CUAUUCUUGAUUACUUGUU------------- 3 1,-2 >hsa-mir-26b MA:12-32;mi:47-68 Normal ccgggacccagUUCAAGUAAUUCAGGAUAGGUugugugcuguccagCCUGUUCUCCAUUACUUGGCUCggggaccgg -----------UUCAAGUAAUUCAGGAUA------------------------------------------------ 39 0,-3 -----------UUCAAGUAAUUCAGGAUAa----------------------------------------------- 25 0,-3 -----------UUCAAGUAAUUCAGGAUAaa---------------------------------------------- 11 0,-3 -----------UUCAAGUAAUUCAGGAUAG----------------------------------------------- 71 0,-2 -----------UUCAAGUAAUUCAGGAUAGa---------------------------------------------- 25 0,-2 -----------UUCAAGUAAUUCAGGAUAGu---------------------------------------------- 2 0,-2 -----------UUCAAGUAAUUCAGGAUAGG---------------------------------------------- 351 0,-1 -----------UUCAAGUAAUUCAGGAUAGGa--------------------------------------------- 131 0,-1 -----------UUCAAGUAAUUCAGGAUAGGaa-------------------------------------------- 96 0,-1 -----------UUCAAGUAAUUCAGGAUAGGau-------------------------------------------- 8 0,-1 -----------UUCAAGUAAUUCAGGAUAGGc--------------------------------------------- 5 0,-1 -----------UUCAAGUAAUUCAGGAUAGGg--------------------------------------------- 2 0,-1 -----------UUCAAGUAAUUCAGGAUAGGU--------------------------------------------- 1658 0,0 -----------UUCAAGUAAUUCAGGAUAGGUa-------------------------------------------- 209 0,0 -----------UUCAAGUAAUUCAGGAUAGGUaa------------------------------------------- 239 0,0 -----------UUCAAGUAAUUCAGGAUAGGUau------------------------------------------- 36 0,0 -----------UUCAAGUAAUUCAGGAUAGGUc-------------------------------------------- 7 0,0 -----------UUCAAGUAAUUCAGGAUAGGUg-------------------------------------------- 6 0,0 -----------UUCAAGUAAUUCAGGAUAGGUU-------------------------------------------- 4379 0,1 -----------UUCAAGUAAUUCAGGAUAGGUUa------------------------------------------- 278 0,1 -----------UUCAAGUAAUUCAGGAUAGGUUaa------------------------------------------ 13 0,1 -----------UUCAAGUAAUUCAGGAUAGGUUau------------------------------------------ 8 0,1 -----------UUCAAGUAAUUCAGGAUAGGUUu------------------------------------------- 319 0,1 -----------UUCAAGUAAUUCAGGAUAGGUUG------------------------------------------- 42 0,2 -----------UUCAAGUAAUUCAGGAUAGGUUGa------------------------------------------ 4 0,2 -----------UUCAAGUAAUUCAGGAUAGGUUGU------------------------------------------ 5 0,3 ------------UCAAGUAAUUCAGGAUAGG---------------------------------------------- 5 1,-1 ------------UCAAGUAAUUCAGGAUAGGU--------------------------------------------- 25 1,0 ------------UCAAGUAAUUCAGGAUAGGUU-------------------------------------------- 70 1,1 ------------UCAAGUAAUUCAGGAUAGGUUu------------------------------------------- 4 1,1 -------------CAAGUAAUUCAGGAUAGGU--------------------------------------------- 2 2,0 -------------CAAGUAAUUCAGGAUAGGUU-------------------------------------------- 4 2,1 ----------------------------------------------CCUGUUCUCCAUUACUUGGCU---------- 13 0,-1 ----------------------------------------------CCUGUUCUCCAUUACUUGGCUC--------- 6 0,0 -----------------------------------------------CUGUUCUCCAUUACUUGGCUCu-------- 2 1,0 >hsa-mir-27a mi:10-31;MA:51-71 Normal cugaggagcAGGGCUUAGCUGCUUGUGAGCAggguccacaccaagucgugUUCACAGUGGCUAAGUUCCGCcccccag ---------AGGGCUUAGCUGCUUGUGAGC------------------------------------------------ 51 0,-1 ---------AGGGCUUAGCUGCUUGUGAGCA----------------------------------------------- 284 0,0 ----------GGGCUUAGCUGCUUGUGAGC------------------------------------------------ 4 1,-1 ----------GGGCUUAGCUGCUUGUGAGCA----------------------------------------------- 7 1,0 --------------------------------------------------UUCACAGUGGCUAAGUUC---------- 229 0,-3 --------------------------------------------------UUCACAGUGGCUAAGUUCa--------- 60 0,-3 --------------------------------------------------UUCACAGUGGCUAAGUUCaa-------- 2 0,-3 --------------------------------------------------UUCACAGUGGCUAAGUUCC--------- 304 0,-2 --------------------------------------------------UUCACAGUGGCUAAGUUCCa-------- 17 0,-2 --------------------------------------------------UUCACAGUGGCUAAGUUCCaa------- 2 0,-2 --------------------------------------------------UUCACAGUGGCUAAGUUCCu-------- 9 0,-2 --------------------------------------------------UUCACAGUGGCUAAGUUCCuu------- 13 0,-2 --------------------------------------------------UUCACAGUGGCUAAGUUCCG-------- 4064 0,-1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGa------- 537 0,-1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGaa------ 71 0,-1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGau------ 31 0,-1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGg------- 13 0,-1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGu------- 676 0,-1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGuu------ 194 0,-1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGC------- 3253 0,0 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCa------ 1161 0,0 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCaa----- 254 0,0 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCau----- 298 0,0 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCg------ 19 0,0 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCu------ 1378 0,0 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCuu----- 142 0,0 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCC------ 6 0,1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCCu----- 4 0,1 ---------------------------------------------------UCACAGUGGCUAAGUUCCG-------- 57 1,-1 ---------------------------------------------------UCACAGUGGCUAAGUUCCGa------- 16 1,-1 ---------------------------------------------------UCACAGUGGCUAAGUUCCGu------- 9 1,-1 ---------------------------------------------------UCACAGUGGCUAAGUUCCGuu------ 2 1,-1 ---------------------------------------------------UCACAGUGGCUAAGUUCCGC------- 67 1,0 ---------------------------------------------------UCACAGUGGCUAAGUUCCGCa------ 19 1,0 ---------------------------------------------------UCACAGUGGCUAAGUUCCGCaa----- 4 1,0 ---------------------------------------------------UCACAGUGGCUAAGUUCCGCau----- 3 1,0 ---------------------------------------------------UCACAGUGGCUAAGUUCCGCu------ 24 1,0 ----------------------------------------------------CACAGUGGCUAAGUUCCG-------- 4 2,-1 ----------------------------------------------------CACAGUGGCUAAGUUCCGC------- 2 2,0 >hsa-mir-27b mi:19-40;MA:61-81 Normal accucucuaacaaggugcAGAGCUUAGCUGAUUGGUGAACagugauugguuuccgcuuugUUCACAGUGGCUAAGUUCUGCaccugaagagaaggug ------------------AGAGCUUAGCUGAUUGGUGA----------------------------------------------------------- 2 0,-2 ------------------AGAGCUUAGCUGAUUGGUGAA---------------------------------------------------------- 3 0,-1 ------------------AGAGCUUAGCUGAUUGGUGAAa--------------------------------------------------------- 6 0,-1 ------------------AGAGCUUAGCUGAUUGGUGAAaa-------------------------------------------------------- 2 0,-1 ------------------AGAGCUUAGCUGAUUGGUGAAC--------------------------------------------------------- 50 0,0 ------------------AGAGCUUAGCUGAUUGGUGAACA-------------------------------------------------------- 29 0,1 -----------------------------------------------------------GUUCACAGUGGCUAAGUUCU------------------ 2 -1,-2 -----------------------------------------------------------GUUCACAGUGGCUAAGUUCUG----------------- 6 -1,-1 -----------------------------------------------------------GUUCACAGUGGCUAAGUUCUGC---------------- 37 -1,0 -----------------------------------------------------------GUUCACAGUGGCUAAGUUCUGCA--------------- 3 -1,1 ------------------------------------------------------------UUCACAGUGGCUAAGUUC------------------- 229 0,-3 ------------------------------------------------------------UUCACAGUGGCUAAGUUCa------------------ 60 0,-3 ------------------------------------------------------------UUCACAGUGGCUAAGUUCaa----------------- 2 0,-3 ------------------------------------------------------------UUCACAGUGGCUAAGUUCU------------------ 308 0,-2 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUa----------------- 7 0,-2 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUu----------------- 6 0,-2 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUuu---------------- 4 0,-2 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUG----------------- 808 0,-1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGa---------------- 340 0,-1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGaa--------------- 68 0,-1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGau--------------- 6 0,-1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGu---------------- 304 0,-1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGuu--------------- 15 0,-1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGC---------------- 3387 0,0 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCc--------------- 7 0,0 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCg--------------- 6 0,0 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCu--------------- 555 0,0 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCuu-------------- 54 0,0 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCA--------------- 1034 0,1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCAa-------------- 325 0,1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCAg-------------- 18 0,1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCAu-------------- 188 0,1 -------------------------------------------------------------UCACAGUGGCUAAGUUCU------------------ 4 1,-2 -------------------------------------------------------------UCACAGUGGCUAAGUUCUG----------------- 11 1,-1 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGa---------------- 5 1,-1 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGC---------------- 71 1,0 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGCu--------------- 15 1,0 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGCA--------------- 27 1,1 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGCAa-------------- 7 1,1 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGCAu-------------- 3 1,1 --------------------------------------------------------------CACAGUGGCUAAGUUCUGC---------------- 4 2,0 --------------------------------------------------------------CACAGUGGCUAAGUUCUGCA--------------- 2 2,1 >hsa-mir-28 5p:14-35;3p:54-75 Normal gguccuugcccucAAGGAGCUCACAGUCUAUUGAGuuaccuuucugacuuuccCACUAGAUUGUGAGCUCCUGGAgggcaggcacu ------------CAAGGAGCUCACAGUCUAUUGA---------------------------------------------------- 17 -1,-1 -------------AAGGAGCUCACAGUCUAU------------------------------------------------------- 7 0,-4 -------------AAGGAGCUCACAGUCUAUU------------------------------------------------------ 37 0,-3 -------------AAGGAGCUCACAGUCUAUUaa---------------------------------------------------- 7 0,-3 -------------AAGGAGCUCACAGUCUAUUG----------------------------------------------------- 109 0,-2 -------------AAGGAGCUCACAGUCUAUUGc---------------------------------------------------- 2 0,-2 -------------AAGGAGCUCACAGUCUAUUGg---------------------------------------------------- 2 0,-2 -------------AAGGAGCUCACAGUCUAUUGu---------------------------------------------------- 16 0,-2 -------------AAGGAGCUCACAGUCUAUUGA---------------------------------------------------- 771 0,-1 -------------AAGGAGCUCACAGUCUAUUGAa--------------------------------------------------- 102 0,-1 -------------AAGGAGCUCACAGUCUAUUGAaa-------------------------------------------------- 14 0,-1 -------------AAGGAGCUCACAGUCUAUUGAu--------------------------------------------------- 9 0,-1 -------------AAGGAGCUCACAGUCUAUUGAG--------------------------------------------------- 603 0,0 -------------AAGGAGCUCACAGUCUAUUGAGa-------------------------------------------------- 153 0,0 -------------AAGGAGCUCACAGUCUAUUGAGaa------------------------------------------------- 2 0,0 -------------AAGGAGCUCACAGUCUAUUGAGU-------------------------------------------------- 40 0,1 --------------AGGAGCUCACAGUCUAUUG----------------------------------------------------- 4 1,-2 --------------AGGAGCUCACAGUCUAUUGA---------------------------------------------------- 14 1,-1 --------------AGGAGCUCACAGUCUAUUGAG--------------------------------------------------- 6 1,0 ----------------------------------------------------CCACUAGAUUGUGAGCUCCUGG------------ 2 -1,-1 -----------------------------------------------------CACUAGAUUGUGAGCUCC--------------- 2 0,-4 -----------------------------------------------------CACUAGAUUGUGAGCUCCU-------------- 7 0,-3 -----------------------------------------------------CACUAGAUUGUGAGCUCCUG------------- 6 0,-2 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGa------------ 6 0,-2 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGaa----------- 2 0,-2 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGu------------ 4 0,-2 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGG------------ 143 0,-1 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGc----------- 2 0,-1 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGu----------- 27 0,-1 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGA----------- 775 0,0 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAa---------- 347 0,0 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAaa--------- 37 0,0 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAau--------- 25 0,0 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAc---------- 2 0,0 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAu---------- 177 0,0 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAuu--------- 5 0,0 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAG---------- 55 0,1 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAGa--------- 3 0,1 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAGu--------- 5 0,1 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGG------------ 12 1,-1 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGA----------- 49 1,0 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGAa---------- 13 1,0 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGAaa--------- 2 1,0 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGAu---------- 5 1,0 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGAG---------- 68 1,1 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGAGa--------- 16 1,1 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGAGu--------- 19 1,1 -------------------------------------------------------CUAGAUUGUGAGCUCCUGGAaa--------- 2 2,0 -------------------------------------------------------CUAGAUUGUGAGCUCCUGGAG---------- 12 2,1 -------------------------------------------------------CUAGAUUGUGAGCUCCUGGAGa--------- 2 2,1 -------------------------------------------------------CUAGAUUGUGAGCUCCUGGAGu--------- 8 2,1 >hsa-mir-296 5p:14-34;3p:48-69 Normal aggacccuuccagAGGGCCCCCCCUCAAUCCUGUugugccuaauucaGAGGGUUGGGUGGAGGCUCUCCugaagggcucu ------------GAGGGCCCCCCCUCAAUCCUGU---------------------------------------------- 2 -1,0 -------------AGGGCCCCCCCUCAAUCCU------------------------------------------------ 2 0,-2 -------------AGGGCCCCCCCUCAAUCCUau---------------------------------------------- 2 0,-2 -------------AGGGCCCCCCCUCAAUCCUGc---------------------------------------------- 2 0,-1 -------------AGGGCCCCCCCUCAAUCCUGU---------------------------------------------- 61 0,0 -----------------------------------------------GAGGGUUGGGUGGAGGCUCU------------- 3 0,-2 -----------------------------------------------GAGGGUUGGGUGGAGGCUCUC------------ 2 0,-1 -----------------------------------------------GAGGGUUGGGUGGAGGCUCUCu----------- 2 0,-1 -----------------------------------------------GAGGGUUGGGUGGAGGCUCUCC----------- 20 0,0 -----------------------------------------------GAGGGUUGGGUGGAGGCUCUCCa---------- 4 0,0 ------------------------------------------------AGGGUUGGGUGGAGGCUCU------------- 19 1,-2 ------------------------------------------------AGGGUUGGGUGGAGGCUCUC------------ 4 1,-1 ------------------------------------------------AGGGUUGGGUGGAGGCUCUCC----------- 21 1,0 ------------------------------------------------AGGGUUGGGUGGAGGCUCUCCa---------- 2 1,0 ------------------------------------------------AGGGUUGGGUGGAGGCUCUCCaa--------- 2 1,0 ------------------------------------------------AGGGUUGGGUGGAGGCUCUCCau--------- 2 1,0 ------------------------------------------------AGGGUUGGGUGGAGGCUCUCCc---------- 12 1,0 ------------------------------------------------AGGGUUGGGUGGAGGCUCUCCU---------- 3 1,1 >hsa-mir-2964a 5p:14-35;3p:56-78 Normal ggagcucagccacAGAUGUCCAGCCACAAUUCUCGguuggccgcagacucguacaAGAAUUGCGUUUGGACAAUCAGUggcgaagccc -------------AGAUGUCCAGCCACAAUUCU------------------------------------------------------- 2 0,-2 -------------------------------------------------------AGAAUUGCGUUUGGACAAUCAGU---------- 2 0,0 >hsa-mir-299 5p:7-28;3p:39-60 Normal aagaaaUGGUUUACCGUCCCACAUACAUuuugaauaugUAUGUGGGAUGGUAAACCGCUUcuu -----AUGGUUUACCGUCCCACAUAC------------------------------------- 10 -1,-2 -----AUGGUUUACCGUCCCACAUACA------------------------------------ 36 -1,-1 -----AUGGUUUACCGUCCCACAUACAa----------------------------------- 2 -1,-1 ------UGGUUUACCGUCCCACAUAC------------------------------------- 15 0,-2 ------UGGUUUACCGUCCCACAUACA------------------------------------ 35 0,-1 ------UGGUUUACCGUCCCACAUACAa----------------------------------- 2 0,-1 ------UGGUUUACCGUCCCACAUACAU----------------------------------- 57 0,0 -------GGUUUACCGUCCCACAUACAU----------------------------------- 4 1,0 -------------------------------------GUAUGUGGGAUGGUAAACCGCU---- 18 -1,-1 --------------------------------------UAUGUGGGAUGGUAAACCGCU---- 6 0,-1 --------------------------------------UAUGUGGGAUGGUAAACCGCUU--- 20 0,0 --------------------------------------UAUGUGGGAUGGUAAACCGCUUu-- 2 0,0 ---------------------------------------AUGUGGGAUGGUAAACCGCU---- 2 1,-1 >hsa-mir-29a mi:4-25;MA:42-63 Normal augACUGAUUUCUUUUGGUGUUCAGagucaauauaauuuucUAGCACCAUCUGAAAUCGGUUAu ---ACUGAUUUCUUUUGGUGUU------------------------------------------ 3 0,-3 ---ACUGAUUUCUUUUGGUGUUC----------------------------------------- 6 0,-2 ---ACUGAUUUCUUUUGGUGUUCA---------------------------------------- 50 0,-1 ---ACUGAUUUCUUUUGGUGUUCAa--------------------------------------- 2 0,-1 ---ACUGAUUUCUUUUGGUGUUCAG--------------------------------------- 43 0,0 ---ACUGAUUUCUUUUGGUGUUCAGu-------------------------------------- 2 0,0 ---ACUGAUUUCUUUUGGUGUUCAGA-------------------------------------- 131 0,1 ---ACUGAUUUCUUUUGGUGUUCAGAG------------------------------------- 5 0,2 ---ACUGAUUUCUUUUGGUGUUCAGAGU------------------------------------ 4 0,3 ----------------------------------------CUAGCACCAUCUGAAAUC------ 2 -1,-5 ----------------------------------------CUAGCACCAUCUGAAAUCG----- 22 -1,-4 ----------------------------------------CUAGCACCAUCUGAAAUCGG---- 33 -1,-3 ----------------------------------------CUAGCACCAUCUGAAAUCGGa--- 2 -1,-3 ----------------------------------------CUAGCACCAUCUGAAAUCGGU--- 294 -1,-2 ----------------------------------------CUAGCACCAUCUGAAAUCGGUa-- 57 -1,-2 ----------------------------------------CUAGCACCAUCUGAAAUCGGUaa- 8 -1,-2 ----------------------------------------CUAGCACCAUCUGAAAUCGGUU-- 1803 -1,-1 ----------------------------------------CUAGCACCAUCUGAAAUCGGUUg- 3 -1,-1 ----------------------------------------CUAGCACCAUCUGAAAUCGGUUu- 75 -1,-1 ----------------------------------------CUAGCACCAUCUGAAAUCGGUUA- 195 -1,0 ----------------------------------------CUAGCACCAUCUGAAAUCGGUUAa 11 -1,0 ----------------------------------------CUAGCACCAUCUGAAAUCGGUUAU 5 -1,1 -----------------------------------------UAGCACCAUCUGAAAUCG----- 98 0,-4 -----------------------------------------UAGCACCAUCUGAAAUCGa---- 23 0,-4 -----------------------------------------UAGCACCAUCUGAAAUCGau--- 2 0,-4 -----------------------------------------UAGCACCAUCUGAAAUCGuu--- 13 0,-4 -----------------------------------------UAGCACCAUCUGAAAUCGG---- 190 0,-3 -----------------------------------------UAGCACCAUCUGAAAUCGGa--- 26 0,-3 -----------------------------------------UAGCACCAUCUGAAAUCGGaa-- 7 0,-3 -----------------------------------------UAGCACCAUCUGAAAUCGGU--- 823 0,-2 -----------------------------------------UAGCACCAUCUGAAAUCGGUa-- 141 0,-2 -----------------------------------------UAGCACCAUCUGAAAUCGGUaa- 184 0,-2 -----------------------------------------UAGCACCAUCUGAAAUCGGUau- 23 0,-2 -----------------------------------------UAGCACCAUCUGAAAUCGGUc-- 18 0,-2 -----------------------------------------UAGCACCAUCUGAAAUCGGUg-- 3 0,-2 -----------------------------------------UAGCACCAUCUGAAAUCGGUU-- 6815 0,-1 -----------------------------------------UAGCACCAUCUGAAAUCGGUUc- 8 0,-1 -----------------------------------------UAGCACCAUCUGAAAUCGGUUg- 46 0,-1 -----------------------------------------UAGCACCAUCUGAAAUCGGUUu- 532 0,-1 -----------------------------------------UAGCACCAUCUGAAAUCGGUUuu 24 0,-1 -----------------------------------------UAGCACCAUCUGAAAUCGGUUA- 6430 0,0 -----------------------------------------UAGCACCAUCUGAAAUCGGUUAa 1618 0,0 -----------------------------------------UAGCACCAUCUGAAAUCGGUUAaa 38 0,0 -----------------------------------------UAGCACCAUCUGAAAUCGGUUAc 12 0,0 -----------------------------------------UAGCACCAUCUGAAAUCGGUUAg 32 0,0 -----------------------------------------UAGCACCAUCUGAAAUCGGUUAU 517 0,1 -----------------------------------------UAGCACCAUCUGAAAUCGGUUAUu 2 0,1 ------------------------------------------AGCACCAUCUGAAAUCGG---- 3 1,-3 ------------------------------------------AGCACCAUCUGAAAUCGGU--- 32 1,-2 ------------------------------------------AGCACCAUCUGAAAUCGGUaa- 7 1,-2 ------------------------------------------AGCACCAUCUGAAAUCGGUU-- 266 1,-1 ------------------------------------------AGCACCAUCUGAAAUCGGUUu- 18 1,-1 ------------------------------------------AGCACCAUCUGAAAUCGGUUA- 251 1,0 ------------------------------------------AGCACCAUCUGAAAUCGGUUAa 69 1,0 ------------------------------------------AGCACCAUCUGAAAUCGGUUAaa 2 1,0 ------------------------------------------AGCACCAUCUGAAAUCGGUUAU 16 1,1 -------------------------------------------GCACCAUCUGAAAUCGGUU-- 15 2,-1 -------------------------------------------GCACCAUCUGAAAUCGGUUA- 13 2,0 -------------------------------------------GCACCAUCUGAAAUCGGUUAa 2 2,0 >hsa-mir-29b-1 mi:10-33;MA:51-73 Normal cuucaggaaGCUGGUUUCAUAUGGUGGUUUAGAuuuaaauagugauugucUAGCACCAUUUGAAAUCAGUGUUcuuggggg ---------GCUGGUUUCAUAUGGUGGUUUAGA------------------------------------------------ 7 0,0 -------------------------------------------------CUAGCACCAUUUGAAAUCA------------- 5 -1,-5 -------------------------------------------------CUAGCACCAUUUGAAAUCAG------------ 10 -1,-4 -------------------------------------------------CUAGCACCAUUUGAAAUCAGU----------- 104 -1,-3 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUu---------- 7 -1,-3 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUG---------- 197 -1,-2 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUGa--------- 66 -1,-2 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUGU--------- 186 -1,-1 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUGUU-------- 15 -1,0 --------------------------------------------------UAGCACCAUUUGAAAUCA------------- 35 0,-5 --------------------------------------------------UAGCACCAUUUGAAAUCAa------------ 2 0,-5 --------------------------------------------------UAGCACCAUUUGAAAUCAG------------ 54 0,-4 --------------------------------------------------UAGCACCAUUUGAAAUCAGa----------- 4 0,-4 --------------------------------------------------UAGCACCAUUUGAAAUCAGU----------- 134 0,-3 --------------------------------------------------UAGCACCAUUUGAAAUCAGUa---------- 2 0,-3 --------------------------------------------------UAGCACCAUUUGAAAUCAGUaa--------- 5 0,-3 --------------------------------------------------UAGCACCAUUUGAAAUCAGUau--------- 3 0,-3 --------------------------------------------------UAGCACCAUUUGAAAUCAGUu---------- 8 0,-3 --------------------------------------------------UAGCACCAUUUGAAAUCAGUuu--------- 6 0,-3 --------------------------------------------------UAGCACCAUUUGAAAUCAGUG---------- 237 0,-2 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGa--------- 169 0,-2 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGaa-------- 7 0,-2 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGc--------- 2 0,-2 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGg--------- 2 0,-2 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGU--------- 2054 0,-1 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGUa-------- 52 0,-1 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGUc-------- 4 0,-1 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGUU-------- 4142 0,0 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGUUa------- 17 0,0 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGUUg------- 10 0,0 ---------------------------------------------------AGCACCAUUUGAAAUCAGU----------- 2 1,-3 ---------------------------------------------------AGCACCAUUUGAAAUCAGUG---------- 3 1,-2 ---------------------------------------------------AGCACCAUUUGAAAUCAGUGa--------- 4 1,-2 ---------------------------------------------------AGCACCAUUUGAAAUCAGUGg--------- 2 1,-2 ---------------------------------------------------AGCACCAUUUGAAAUCAGUGU--------- 82 1,-1 ---------------------------------------------------AGCACCAUUUGAAAUCAGUGUU-------- 150 1,0 ---------------------------------------------------AGCACCAUUUGAAAUCAGUGUUa------- 2 1,0 ---------------------------------------------------AGCACCAUUUGAAAUCAGUGUUg------- 2 1,0 ----------------------------------------------------GCACCAUUUGAAAUCAGUGU--------- 4 2,-1 ----------------------------------------------------GCACCAUUUGAAAUCAGUGUU-------- 8 2,0 >hsa-mir-29b-2 mi:11-32;MA:52-74 Normal cuucuggaagCUGGUUUCACAUGGUGGCUUAGauuuuuccaucuuuguaucUAGCACCAUUUGAAAUCAGUGUUuuaggag ---------GCUGGUUUCACAUGGUGGCUUAG------------------------------------------------- 5 -1,0 ---------GCUGGUUUCACAUGGUGGCUUAGA------------------------------------------------ 2 -1,1 ----------CUGGUUUCACAUGGUGGCUUAG------------------------------------------------- 18 0,0 ----------CUGGUUUCACAUGGUGGCUUAGu------------------------------------------------ 3 0,0 ----------CUGGUUUCACAUGGUGGCUUAGA------------------------------------------------ 59 0,1 ----------CUGGUUUCACAUGGUGGCUUAGAU----------------------------------------------- 2 0,2 -----------UGGUUUCACAUGGUGGCUUAGA------------------------------------------------ 2 1,1 -----------UGGUUUCACAUGGUGGCUUAGAU----------------------------------------------- 2 1,2 --------------------------------------------------CUAGCACCAUUUGAAAUCA------------ 5 -1,-5 --------------------------------------------------CUAGCACCAUUUGAAAUCAG----------- 10 -1,-4 --------------------------------------------------CUAGCACCAUUUGAAAUCAGU---------- 104 -1,-3 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUu--------- 7 -1,-3 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUG--------- 197 -1,-2 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUGa-------- 66 -1,-2 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUGU-------- 186 -1,-1 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUGUU------- 15 -1,0 ---------------------------------------------------UAGCACCAUUUGAAAUCA------------ 35 0,-5 ---------------------------------------------------UAGCACCAUUUGAAAUCAa----------- 2 0,-5 ---------------------------------------------------UAGCACCAUUUGAAAUCAG----------- 54 0,-4 ---------------------------------------------------UAGCACCAUUUGAAAUCAGa---------- 4 0,-4 ---------------------------------------------------UAGCACCAUUUGAAAUCAGU---------- 134 0,-3 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUa--------- 2 0,-3 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUaa-------- 5 0,-3 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUau-------- 3 0,-3 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUu--------- 8 0,-3 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUuu-------- 6 0,-3 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUG--------- 237 0,-2 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGa-------- 169 0,-2 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGaa------- 7 0,-2 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGc-------- 2 0,-2 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGg-------- 2 0,-2 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGU-------- 2054 0,-1 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUa------- 52 0,-1 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUc------- 4 0,-1 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUU------- 4142 0,0 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUUa------ 17 0,0 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUUg------ 10 0,0 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUUU------ 56 0,1 ----------------------------------------------------AGCACCAUUUGAAAUCAGU---------- 2 1,-3 ----------------------------------------------------AGCACCAUUUGAAAUCAGUG--------- 3 1,-2 ----------------------------------------------------AGCACCAUUUGAAAUCAGUGa-------- 4 1,-2 ----------------------------------------------------AGCACCAUUUGAAAUCAGUGg-------- 2 1,-2 ----------------------------------------------------AGCACCAUUUGAAAUCAGUGU-------- 82 1,-1 ----------------------------------------------------AGCACCAUUUGAAAUCAGUGUU------- 150 1,0 ----------------------------------------------------AGCACCAUUUGAAAUCAGUGUUa------ 2 1,0 ----------------------------------------------------AGCACCAUUUGAAAUCAGUGUUg------ 2 1,0 -----------------------------------------------------GCACCAUUUGAAAUCAGUGU-------- 4 2,-1 -----------------------------------------------------GCACCAUUUGAAAUCAGUGUU------- 8 2,0 >hsa-mir-29c mi:16-37;MA:54-75 Normal aucucuuacacaggcUGACCGAUUUCUCCUGGUGUUCagagucuguuuuugucUAGCACCAUUUGAAAUCGGUUAugauguaggggga --------------CUGACCGAUUUCUCCUGGUGUU---------------------------------------------------- 2 -1,-1 ---------------UGACCGAUUUCUCCUGGU------------------------------------------------------- 2 0,-4 ---------------UGACCGAUUUCUCCUGGUuu----------------------------------------------------- 2 0,-4 ---------------UGACCGAUUUCUCCUGGUGU----------------------------------------------------- 43 0,-2 ---------------UGACCGAUUUCUCCUGGUGUU---------------------------------------------------- 214 0,-1 ---------------UGACCGAUUUCUCCUGGUGUUa--------------------------------------------------- 33 0,-1 ---------------UGACCGAUUUCUCCUGGUGUUaa-------------------------------------------------- 4 0,-1 ---------------UGACCGAUUUCUCCUGGUGUUu--------------------------------------------------- 38 0,-1 ---------------UGACCGAUUUCUCCUGGUGUUC--------------------------------------------------- 79 0,0 ---------------UGACCGAUUUCUCCUGGUGUUCu-------------------------------------------------- 11 0,0 ---------------UGACCGAUUUCUCCUGGUGUUCA-------------------------------------------------- 15 0,1 ----------------GACCGAUUUCUCCUGGUGU----------------------------------------------------- 4 1,-2 ----------------GACCGAUUUCUCCUGGUGUU---------------------------------------------------- 49 1,-1 ----------------GACCGAUUUCUCCUGGUGUUa--------------------------------------------------- 2 1,-1 ----------------GACCGAUUUCUCCUGGUGUUu--------------------------------------------------- 5 1,-1 ----------------GACCGAUUUCUCCUGGUGUUC--------------------------------------------------- 48 1,0 ----------------GACCGAUUUCUCCUGGUGUUCA-------------------------------------------------- 39 1,1 ----------------GACCGAUUUCUCCUGGUGUUCAa------------------------------------------------- 2 1,1 ----------------GACCGAUUUCUCCUGGUGUUCAG------------------------------------------------- 8 1,2 ----------------GACCGAUUUCUCCUGGUGUUCAGA------------------------------------------------ 2 1,3 -----------------ACCGAUUUCUCCUGGUGUU---------------------------------------------------- 6 2,-1 -----------------ACCGAUUUCUCCUGGUGUUC--------------------------------------------------- 11 2,0 -----------------ACCGAUUUCUCCUGGUGUUCA-------------------------------------------------- 14 2,1 -----------------ACCGAUUUCUCCUGGUGUUCAG------------------------------------------------- 30 2,2 -----------------ACCGAUUUCUCCUGGUGUUCAGu------------------------------------------------ 6 2,2 -----------------ACCGAUUUCUCCUGGUGUUCAGA------------------------------------------------ 80 2,3 ----------------------------------------------------CUAGCACCAUUUGAAAUC------------------ 2 -1,-5 ----------------------------------------------------CUAGCACCAUUUGAAAUCGGUU-------------- 17 -1,-1 ----------------------------------------------------CUAGCACCAUUUGAAAUCGGUUA------------- 4 -1,0 -----------------------------------------------------UAGCACCAUUUGAAAUCG----------------- 40 0,-4 -----------------------------------------------------UAGCACCAUUUGAAAUCGa---------------- 3 0,-4 -----------------------------------------------------UAGCACCAUUUGAAAUCGuu--------------- 3 0,-4 -----------------------------------------------------UAGCACCAUUUGAAAUCGG---------------- 58 0,-3 -----------------------------------------------------UAGCACCAUUUGAAAUCGGa--------------- 11 0,-3 -----------------------------------------------------UAGCACCAUUUGAAAUCGGaa-------------- 4 0,-3 -----------------------------------------------------UAGCACCAUUUGAAAUCGGU--------------- 373 0,-2 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUa-------------- 42 0,-2 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUaa------------- 53 0,-2 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUau------------- 3 0,-2 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUc-------------- 6 0,-2 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUU-------------- 2611 0,-1 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUg------------- 18 0,-1 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUu------------- 162 0,-1 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUuu------------ 16 0,-1 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUA------------- 1407 0,0 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUAa------------ 502 0,0 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUAaa----------- 4 0,0 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUAc------------ 3 0,0 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUAg------------ 15 0,0 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUAU------------ 167 0,1 ------------------------------------------------------AGCACCAUUUGAAAUCGG---------------- 3 1,-3 ------------------------------------------------------AGCACCAUUUGAAAUCGGU--------------- 13 1,-2 ------------------------------------------------------AGCACCAUUUGAAAUCGGUaa------------- 2 1,-2 ------------------------------------------------------AGCACCAUUUGAAAUCGGUU-------------- 96 1,-1 ------------------------------------------------------AGCACCAUUUGAAAUCGGUUu------------- 2 1,-1 ------------------------------------------------------AGCACCAUUUGAAAUCGGUUuu------------ 2 1,-1 ------------------------------------------------------AGCACCAUUUGAAAUCGGUUA------------- 38 1,0 ------------------------------------------------------AGCACCAUUUGAAAUCGGUUAa------------ 16 1,0 ------------------------------------------------------AGCACCAUUUGAAAUCGGUUAU------------ 5 1,1 -------------------------------------------------------GCACCAUUUGAAAUCGGUU-------------- 4 2,-1 -------------------------------------------------------GCACCAUUUGAAAUCGGUUuu------------ 2 2,-1 -------------------------------------------------------GCACCAUUUGAAAUCGGUUA------------- 3 2,0 -------------------------------------------------------GCACCAUUUGAAAUCGGUUAUu----------- 4 2,1 >hsa-mir-301a 3pM:51-73 Normal acugcuaacgaaugcucugacuuuauugcacuacuguacuuuacagcuagCAGUGCAAUAGUAUUGUCAAAGCaucugaaagcagg --------------------------------------------------CAGUGCAAUAGUAUUGUCA----------------- 6 0,-4 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAA--------------- 5 0,-2 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAG-------------- 68 0,-1 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAGa------------- 2 0,-1 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAGC------------- 71 0,0 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAGCA------------ 8 0,1 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAGCAU----------- 4 0,2 ---------------------------------------------------AGUGCAAUAGUAUUGUCAAAGC------------- 3 1,0 >hsa-mir-301b 3pM:45-67 Normal gccgcaggugcucugacgagguugcacuacugugcucugagaagCAGUGCAAUGAUAUUGUCAAAGCaucugggacca --------------------------------------------CAGUGCAAUGAUAUUGUCAAA------------- 2 0,-2 --------------------------------------------CAGUGCAAUGAUAUUGUCAAAG------------ 5 0,-1 --------------------------------------------CAGUGCAAUGAUAUUGUCAAAGCA---------- 2 0,1 >hsa-mir-3065 5p:10-32;3p:50-72 Normal cugcccucuUCAACAAAAUCACUGAUGCUGGAgucgccugagucaucacUCAGCACCAGGAUAUUGUUGGAGaggacag ---------UCAACAAAAUCACUGAUGCUGG------------------------------------------------ 7 0,-1 -------------------------------------------------UCAGCACCAGGAUAUUGUUGGA-------- 4 0,-1 >hsa-mir-30a MA:6-27;mi:47-68 Normal gcgacUGUAAACAUCCUCGACUGGAAGcugugaagccacagaugggCUUUCAGUCGGAUGUUUGCAGCugc ----CUGUAAACAUCCUCGACUGGA---------------------------------------------- 4 -1,-2 ----CUGUAAACAUCCUCGACUGGAAGC------------------------------------------- 2 -1,1 -----UGUAAACAUCCUCGACUG------------------------------------------------ 78 0,-4 -----UGUAAACAUCCUCGACUGa----------------------------------------------- 14 0,-4 -----UGUAAACAUCCUCGACUGaa---------------------------------------------- 3 0,-4 -----UGUAAACAUCCUCGACUGu----------------------------------------------- 9 0,-4 -----UGUAAACAUCCUCGACUGG----------------------------------------------- 220 0,-3 -----UGUAAACAUCCUCGACUGGc---------------------------------------------- 5 0,-3 -----UGUAAACAUCCUCGACUGGA---------------------------------------------- 2109 0,-2 -----UGUAAACAUCCUCGACUGGAc--------------------------------------------- 3 0,-2 -----UGUAAACAUCCUCGACUGGAg--------------------------------------------- 10 0,-2 -----UGUAAACAUCCUCGACUGGAu--------------------------------------------- 17 0,-2 -----UGUAAACAUCCUCGACUGGAA--------------------------------------------- 2317 0,-1 -----UGUAAACAUCCUCGACUGGAAa-------------------------------------------- 624 0,-1 -----UGUAAACAUCCUCGACUGGAAaa------------------------------------------- 23 0,-1 -----UGUAAACAUCCUCGACUGGAAau------------------------------------------- 5 0,-1 -----UGUAAACAUCCUCGACUGGAAc-------------------------------------------- 2 0,-1 -----UGUAAACAUCCUCGACUGGAAu-------------------------------------------- 36 0,-1 -----UGUAAACAUCCUCGACUGGAAuu------------------------------------------- 2 0,-1 -----UGUAAACAUCCUCGACUGGAAG-------------------------------------------- 3649 0,0 -----UGUAAACAUCCUCGACUGGAAGa------------------------------------------- 440 0,0 -----UGUAAACAUCCUCGACUGGAAGaa------------------------------------------ 9 0,0 -----UGUAAACAUCCUCGACUGGAAGau------------------------------------------ 12 0,0 -----UGUAAACAUCCUCGACUGGAAGg------------------------------------------- 3 0,0 -----UGUAAACAUCCUCGACUGGAAGu------------------------------------------- 301 0,0 -----UGUAAACAUCCUCGACUGGAAGuu------------------------------------------ 11 0,0 -----UGUAAACAUCCUCGACUGGAAGC------------------------------------------- 3088 0,1 -----UGUAAACAUCCUCGACUGGAAGCa------------------------------------------ 88 0,1 -----UGUAAACAUCCUCGACUGGAAGCc------------------------------------------ 6 0,1 -----UGUAAACAUCCUCGACUGGAAGCg------------------------------------------ 5 0,1 -----UGUAAACAUCCUCGACUGGAAGCU------------------------------------------ 3274 0,2 -----UGUAAACAUCCUCGACUGGAAGCUa----------------------------------------- 7 0,2 -----UGUAAACAUCCUCGACUGGAAGCUu----------------------------------------- 73 0,2 ------GUAAACAUCCUCGACUGG----------------------------------------------- 2 1,-3 ------GUAAACAUCCUCGACUGGA---------------------------------------------- 43 1,-2 ------GUAAACAUCCUCGACUGGAA--------------------------------------------- 41 1,-1 ------GUAAACAUCCUCGACUGGAAa-------------------------------------------- 6 1,-1 ------GUAAACAUCCUCGACUGGAAG-------------------------------------------- 96 1,0 ------GUAAACAUCCUCGACUGGAAGa------------------------------------------- 5 1,0 ------GUAAACAUCCUCGACUGGAAGu------------------------------------------- 2 1,0 ------GUAAACAUCCUCGACUGGAAGC------------------------------------------- 40 1,1 ------GUAAACAUCCUCGACUGGAAGCa------------------------------------------ 7 1,1 ------GUAAACAUCCUCGACUGGAAGCU------------------------------------------ 193 1,2 ----------------------------------------------CUUUCAGUCGGAUGUUUG------- 13 0,-4 ----------------------------------------------CUUUCAGUCGGAUGUUUGa------ 10 0,-4 ----------------------------------------------CUUUCAGUCGGAUGUUUGC------ 74 0,-3 ----------------------------------------------CUUUCAGUCGGAUGUUUGCA----- 216 0,-2 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAa---- 73 0,-2 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAaa--- 6 0,-2 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAuu--- 2 0,-2 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAG---- 494 0,-1 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGa--- 108 0,-1 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGaa-- 5 0,-1 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGu--- 629 0,-1 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGuu-- 24 0,-1 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGC--- 753 0,0 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGCa-- 130 0,0 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGCaa- 5 0,0 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGCau- 11 0,0 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGCU-- 13 0,1 -----------------------------------------------UUUCAGUCGGAUGUUUGCA----- 5 1,-2 -----------------------------------------------UUUCAGUCGGAUGUUUGCAa---- 11 1,-2 -----------------------------------------------UUUCAGUCGGAUGUUUGCAG---- 72 1,-1 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGa--- 11 1,-1 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGu--- 140 1,-1 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGuu-- 20 1,-1 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGC--- 111 1,0 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGCa-- 35 1,0 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGCau- 7 1,0 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGCU-- 39 1,1 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGCUa- 2 1,1 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGCUu- 2 1,1 ------------------------------------------------UUCAGUCGGAUGUUUGCAGu--- 2 2,-1 >hsa-mir-30b MA:17-38;mi:55-76 Normal accaaguuucaguucaUGUAAACAUCCUACACUCAGCUguaauacauggauuggCUGGGAGGUGGAUGUUUACUUCagcugacuugga ----------------UGUAAACAUCCUACACUC------------------------------------------------------ 59 0,-4 ----------------UGUAAACAUCCUACACUCA----------------------------------------------------- 64 0,-3 ----------------UGUAAACAUCCUACACUCAa---------------------------------------------------- 2 0,-3 ----------------UGUAAACAUCCUACACUCAG---------------------------------------------------- 46 0,-2 ----------------UGUAAACAUCCUACACUCAGa--------------------------------------------------- 80 0,-2 ----------------UGUAAACAUCCUACACUCAGaa-------------------------------------------------- 7 0,-2 ----------------UGUAAACAUCCUACACUCAGau-------------------------------------------------- 7 0,-2 ----------------UGUAAACAUCCUACACUCAGu--------------------------------------------------- 4 0,-2 ----------------UGUAAACAUCCUACACUCAGuu-------------------------------------------------- 8 0,-2 ----------------UGUAAACAUCCUACACUCAGC--------------------------------------------------- 1220 0,-1 ----------------UGUAAACAUCCUACACUCAGCa-------------------------------------------------- 34 0,-1 ----------------UGUAAACAUCCUACACUCAGCaa------------------------------------------------- 6 0,-1 ----------------UGUAAACAUCCUACACUCAGCc-------------------------------------------------- 12 0,-1 ----------------UGUAAACAUCCUACACUCAGCg-------------------------------------------------- 2 0,-1 ----------------UGUAAACAUCCUACACUCAGCU-------------------------------------------------- 5473 0,0 ----------------UGUAAACAUCCUACACUCAGCUa------------------------------------------------- 82 0,0 ----------------UGUAAACAUCCUACACUCAGCUu------------------------------------------------- 104 0,0 ----------------UGUAAACAUCCUACACUCAGCUuu------------------------------------------------ 5 0,0 ----------------UGUAAACAUCCUACACUCAGCUG------------------------------------------------- 15 0,1 ----------------UGUAAACAUCCUACACUCAGCUGU------------------------------------------------ 2 0,2 -----------------GUAAACAUCCUACACUCAG---------------------------------------------------- 2 1,-2 -----------------GUAAACAUCCUACACUCAGC--------------------------------------------------- 52 1,-1 -----------------GUAAACAUCCUACACUCAGCU-------------------------------------------------- 173 1,0 -----------------GUAAACAUCCUACACUCAGCUa------------------------------------------------- 2 1,0 ------------------------------------------------------CUGGGAGGUGGAUGUUUACUU------------- 5 0,-1 ------------------------------------------------------CUGGGAGGUGGAUGUUUACUUa------------ 2 0,-1 ------------------------------------------------------CUGGGAGGUGGAUGUUUACUUC------------ 9 0,0 ------------------------------------------------------CUGGGAGGUGGAUGUUUACUUCu----------- 4 0,0 ------------------------------------------------------CUGGGAGGUGGAUGUUUACUUCA----------- 2 0,1 >hsa-mir-30c-1 MA:17-39;mi:56-77 Normal accaugcuguagugugUGUAAACAUCCUACACUCUCAGCugugagcucaagguggCUGGGAGAGGGUUGUUUACUCCuucugccaugga ----------------UGUAAACAUCCUACACUC------------------------------------------------------- 59 0,-5 ----------------UGUAAACAUCCUACACUCU------------------------------------------------------ 114 0,-4 ----------------UGUAAACAUCCUACACUCUC----------------------------------------------------- 102 0,-3 ----------------UGUAAACAUCCUACACUCUCu---------------------------------------------------- 4 0,-3 ----------------UGUAAACAUCCUACACUCUCA---------------------------------------------------- 513 0,-2 ----------------UGUAAACAUCCUACACUCUCAa--------------------------------------------------- 19 0,-2 ----------------UGUAAACAUCCUACACUCUCAaa-------------------------------------------------- 3 0,-2 ----------------UGUAAACAUCCUACACUCUCAu--------------------------------------------------- 5 0,-2 ----------------UGUAAACAUCCUACACUCUCAG--------------------------------------------------- 406 0,-1 ----------------UGUAAACAUCCUACACUCUCAGa-------------------------------------------------- 256 0,-1 ----------------UGUAAACAUCCUACACUCUCAGaa------------------------------------------------- 3 0,-1 ----------------UGUAAACAUCCUACACUCUCAGg-------------------------------------------------- 2 0,-1 ----------------UGUAAACAUCCUACACUCUCAGu-------------------------------------------------- 77 0,-1 ----------------UGUAAACAUCCUACACUCUCAGuu------------------------------------------------- 2 0,-1 ----------------UGUAAACAUCCUACACUCUCAGC-------------------------------------------------- 1695 0,0 ----------------UGUAAACAUCCUACACUCUCAGCa------------------------------------------------- 42 0,0 ----------------UGUAAACAUCCUACACUCUCAGCc------------------------------------------------- 2 0,0 ----------------UGUAAACAUCCUACACUCUCAGCg------------------------------------------------- 7 0,0 ----------------UGUAAACAUCCUACACUCUCAGCU------------------------------------------------- 2059 0,1 ----------------UGUAAACAUCCUACACUCUCAGCUa------------------------------------------------ 9 0,1 ----------------UGUAAACAUCCUACACUCUCAGCUu------------------------------------------------ 35 0,1 -----------------GUAAACAUCCUACACUCU------------------------------------------------------ 3 1,-4 -----------------GUAAACAUCCUACACUCUCA---------------------------------------------------- 16 1,-2 -----------------GUAAACAUCCUACACUCUCAG--------------------------------------------------- 7 1,-1 -----------------GUAAACAUCCUACACUCUCAGa-------------------------------------------------- 10 1,-1 -----------------GUAAACAUCCUACACUCUCAGu-------------------------------------------------- 2 1,-1 -----------------GUAAACAUCCUACACUCUCAGC-------------------------------------------------- 64 1,0 -----------------GUAAACAUCCUACACUCUCAGCU------------------------------------------------- 75 1,1 -------------------------------------------------------CUGGGAGAGGGUUGUUUACa-------------- 2 0,-3 -------------------------------------------------------CUGGGAGAGGGUUGUUUACU-------------- 2 0,-2 -------------------------------------------------------CUGGGAGAGGGUUGUUUACUC------------- 4 0,-1 -------------------------------------------------------CUGGGAGAGGGUUGUUUACUCu------------ 5 0,-1 -------------------------------------------------------CUGGGAGAGGGUUGUUUACUCC------------ 16 0,0 -------------------------------------------------------CUGGGAGAGGGUUGUUUACUCCa----------- 3 0,0 -------------------------------------------------------CUGGGAGAGGGUUGUUUACUCCU----------- 5 0,1 >hsa-mir-30c-2 MA:7-29;mi:47-68 Normal agauacUGUAAACAUCCUACACUCUCAGCuguggaaaguaagaaagCUGGGAGAAGGCUGUUUACUCUuucu -----CUGUAAACAUCCUACACUC------------------------------------------------ 12 -1,-5 -----CUGUAAACAUCCUACACUCUCAGC------------------------------------------- 5 -1,0 -----CUGUAAACAUCCUACACUCUCAGCU------------------------------------------ 5 -1,1 ------UGUAAACAUCCUACACUC------------------------------------------------ 59 0,-5 ------UGUAAACAUCCUACACUCU----------------------------------------------- 114 0,-4 ------UGUAAACAUCCUACACUCUC---------------------------------------------- 102 0,-3 ------UGUAAACAUCCUACACUCUCu--------------------------------------------- 4 0,-3 ------UGUAAACAUCCUACACUCUCA--------------------------------------------- 513 0,-2 ------UGUAAACAUCCUACACUCUCAa-------------------------------------------- 19 0,-2 ------UGUAAACAUCCUACACUCUCAaa------------------------------------------- 3 0,-2 ------UGUAAACAUCCUACACUCUCAu-------------------------------------------- 5 0,-2 ------UGUAAACAUCCUACACUCUCAG-------------------------------------------- 406 0,-1 ------UGUAAACAUCCUACACUCUCAGa------------------------------------------- 256 0,-1 ------UGUAAACAUCCUACACUCUCAGaa------------------------------------------ 3 0,-1 ------UGUAAACAUCCUACACUCUCAGg------------------------------------------- 2 0,-1 ------UGUAAACAUCCUACACUCUCAGu------------------------------------------- 77 0,-1 ------UGUAAACAUCCUACACUCUCAGuu------------------------------------------ 2 0,-1 ------UGUAAACAUCCUACACUCUCAGC------------------------------------------- 1695 0,0 ------UGUAAACAUCCUACACUCUCAGCa------------------------------------------ 42 0,0 ------UGUAAACAUCCUACACUCUCAGCc------------------------------------------ 2 0,0 ------UGUAAACAUCCUACACUCUCAGCg------------------------------------------ 7 0,0 ------UGUAAACAUCCUACACUCUCAGCU------------------------------------------ 2059 0,1 ------UGUAAACAUCCUACACUCUCAGCUa----------------------------------------- 9 0,1 ------UGUAAACAUCCUACACUCUCAGCUu----------------------------------------- 35 0,1 -------GUAAACAUCCUACACUCU----------------------------------------------- 3 1,-4 -------GUAAACAUCCUACACUCUCA--------------------------------------------- 16 1,-2 -------GUAAACAUCCUACACUCUCAG-------------------------------------------- 7 1,-1 -------GUAAACAUCCUACACUCUCAGa------------------------------------------- 10 1,-1 -------GUAAACAUCCUACACUCUCAGu------------------------------------------- 2 1,-1 -------GUAAACAUCCUACACUCUCAGC------------------------------------------- 64 1,0 -------GUAAACAUCCUACACUCUCAGCU------------------------------------------ 75 1,1 ----------------------------------------------CUGGGAGAAGGCUGUUUACU------ 42 0,-2 ----------------------------------------------CUGGGAGAAGGCUGUUUACUC----- 19 0,-1 ----------------------------------------------CUGGGAGAAGGCUGUUUACUCaa--- 2 0,-1 ----------------------------------------------CUGGGAGAAGGCUGUUUACUCU---- 154 0,0 -----------------------------------------------UGGGAGAAGGCUGUUUACUCU---- 6 1,0 >hsa-mir-30d MA:6-27;mi:46-67 Normal guuguUGUAAACAUCCCCGACUGGAAGcuguaagacacagcuaagCUUUCAGUCAGAUGUUUGCUGCuac -----UGUAAACAUCCCCGACUG----------------------------------------------- 28 0,-4 -----UGUAAACAUCCCCGACUGa---------------------------------------------- 2 0,-4 -----UGUAAACAUCCCCGACUGaa--------------------------------------------- 2 0,-4 -----UGUAAACAUCCCCGACUGu---------------------------------------------- 5 0,-4 -----UGUAAACAUCCCCGACUGG---------------------------------------------- 165 0,-3 -----UGUAAACAUCCCCGACUGGc--------------------------------------------- 5 0,-3 -----UGUAAACAUCCCCGACUGGA--------------------------------------------- 1328 0,-2 -----UGUAAACAUCCCCGACUGGAc-------------------------------------------- 3 0,-2 -----UGUAAACAUCCCCGACUGGAg-------------------------------------------- 6 0,-2 -----UGUAAACAUCCCCGACUGGAu-------------------------------------------- 6 0,-2 -----UGUAAACAUCCCCGACUGGAA-------------------------------------------- 1197 0,-1 -----UGUAAACAUCCCCGACUGGAAa------------------------------------------- 464 0,-1 -----UGUAAACAUCCCCGACUGGAAaa------------------------------------------ 41 0,-1 -----UGUAAACAUCCCCGACUGGAAc------------------------------------------- 4 0,-1 -----UGUAAACAUCCCCGACUGGAAu------------------------------------------- 40 0,-1 -----UGUAAACAUCCCCGACUGGAAG------------------------------------------- 1500 0,0 -----UGUAAACAUCCCCGACUGGAAGa------------------------------------------ 265 0,0 -----UGUAAACAUCCCCGACUGGAAGaa----------------------------------------- 5 0,0 -----UGUAAACAUCCCCGACUGGAAGau----------------------------------------- 4 0,0 -----UGUAAACAUCCCCGACUGGAAGg------------------------------------------ 2 0,0 -----UGUAAACAUCCCCGACUGGAAGu------------------------------------------ 158 0,0 -----UGUAAACAUCCCCGACUGGAAGuu----------------------------------------- 4 0,0 -----UGUAAACAUCCCCGACUGGAAGC------------------------------------------ 1389 0,1 -----UGUAAACAUCCCCGACUGGAAGCa----------------------------------------- 36 0,1 -----UGUAAACAUCCCCGACUGGAAGCc----------------------------------------- 2 0,1 -----UGUAAACAUCCCCGACUGGAAGCU----------------------------------------- 1140 0,2 -----UGUAAACAUCCCCGACUGGAAGCUa---------------------------------------- 4 0,2 -----UGUAAACAUCCCCGACUGGAAGCUu---------------------------------------- 35 0,2 ------GUAAACAUCCCCGACUGG---------------------------------------------- 6 1,-3 ------GUAAACAUCCCCGACUGGc--------------------------------------------- 2 1,-3 ------GUAAACAUCCCCGACUGGA--------------------------------------------- 43 1,-2 ------GUAAACAUCCCCGACUGGAA-------------------------------------------- 37 1,-1 ------GUAAACAUCCCCGACUGGAAa------------------------------------------- 16 1,-1 ------GUAAACAUCCCCGACUGGAAaa------------------------------------------ 2 1,-1 ------GUAAACAUCCCCGACUGGAAG------------------------------------------- 60 1,0 ------GUAAACAUCCCCGACUGGAAGa------------------------------------------ 3 1,0 ------GUAAACAUCCCCGACUGGAAGu------------------------------------------ 7 1,0 ------GUAAACAUCCCCGACUGGAAGC------------------------------------------ 57 1,1 ------GUAAACAUCCCCGACUGGAAGCU----------------------------------------- 37 1,2 ---------------------------------------------CUUUCAGUCAGAUGUUUGC------ 2 0,-3 ---------------------------------------------CUUUCAGUCAGAUGUUUGCU----- 2 0,-2 ---------------------------------------------CUUUCAGUCAGAUGUUUGCUG---- 2 0,-1 ---------------------------------------------CUUUCAGUCAGAUGUUUGCUGu--- 2 0,-1 ---------------------------------------------CUUUCAGUCAGAUGUUUGCUGC--- 49 0,0 ---------------------------------------------CUUUCAGUCAGAUGUUUGCUGCa-- 3 0,0 ---------------------------------------------CUUUCAGUCAGAUGUUUGCUGCU-- 12 0,1 ---------------------------------------------CUUUCAGUCAGAUGUUUGCUGCUu- 2 0,1 ----------------------------------------------UUUCAGUCAGAUGUUUGCU----- 2 1,-2 ----------------------------------------------UUUCAGUCAGAUGUUUGCUGC--- 6 1,0 ----------------------------------------------UUUCAGUCAGAUGUUUGCUGCU-- 4 1,1 >hsa-mir-30e MA:17-38;mi:59-80 Normal gggcagucuuugcuacUGUAAACAUCCUUGACUGGAAGcuguaagguguucagaggagCUUUCAGUCGGAUGUUUACAGCggcaggcugcca ----------------UGUAAACAUCCUUGACUG---------------------------------------------------------- 30 0,-4 ----------------UGUAAACAUCCUUGACUGa--------------------------------------------------------- 5 0,-4 ----------------UGUAAACAUCCUUGACUGaa-------------------------------------------------------- 5 0,-4 ----------------UGUAAACAUCCUUGACUGG--------------------------------------------------------- 217 0,-3 ----------------UGUAAACAUCCUUGACUGGu-------------------------------------------------------- 3 0,-3 ----------------UGUAAACAUCCUUGACUGGA-------------------------------------------------------- 1417 0,-2 ----------------UGUAAACAUCCUUGACUGGAg------------------------------------------------------- 9 0,-2 ----------------UGUAAACAUCCUUGACUGGAu------------------------------------------------------- 11 0,-2 ----------------UGUAAACAUCCUUGACUGGAA------------------------------------------------------- 837 0,-1 ----------------UGUAAACAUCCUUGACUGGAAa------------------------------------------------------ 391 0,-1 ----------------UGUAAACAUCCUUGACUGGAAaa----------------------------------------------------- 32 0,-1 ----------------UGUAAACAUCCUUGACUGGAAau----------------------------------------------------- 8 0,-1 ----------------UGUAAACAUCCUUGACUGGAAu------------------------------------------------------ 42 0,-1 ----------------UGUAAACAUCCUUGACUGGAAuu----------------------------------------------------- 4 0,-1 ----------------UGUAAACAUCCUUGACUGGAAG------------------------------------------------------ 1703 0,0 ----------------UGUAAACAUCCUUGACUGGAAGa----------------------------------------------------- 294 0,0 ----------------UGUAAACAUCCUUGACUGGAAGaa---------------------------------------------------- 2 0,0 ----------------UGUAAACAUCCUUGACUGGAAGau---------------------------------------------------- 12 0,0 ----------------UGUAAACAUCCUUGACUGGAAGg----------------------------------------------------- 2 0,0 ----------------UGUAAACAUCCUUGACUGGAAGu----------------------------------------------------- 208 0,0 ----------------UGUAAACAUCCUUGACUGGAAGuu---------------------------------------------------- 8 0,0 ----------------UGUAAACAUCCUUGACUGGAAGC----------------------------------------------------- 1574 0,1 ----------------UGUAAACAUCCUUGACUGGAAGCa---------------------------------------------------- 66 0,1 ----------------UGUAAACAUCCUUGACUGGAAGCc---------------------------------------------------- 6 0,1 ----------------UGUAAACAUCCUUGACUGGAAGCg---------------------------------------------------- 5 0,1 ----------------UGUAAACAUCCUUGACUGGAAGCU---------------------------------------------------- 2504 0,2 ----------------UGUAAACAUCCUUGACUGGAAGCUa--------------------------------------------------- 6 0,2 ----------------UGUAAACAUCCUUGACUGGAAGCUu--------------------------------------------------- 52 0,2 -----------------GUAAACAUCCUUGACUGG--------------------------------------------------------- 5 1,-3 -----------------GUAAACAUCCUUGACUGGA-------------------------------------------------------- 31 1,-2 -----------------GUAAACAUCCUUGACUGGAA------------------------------------------------------- 37 1,-1 -----------------GUAAACAUCCUUGACUGGAAa------------------------------------------------------ 19 1,-1 -----------------GUAAACAUCCUUGACUGGAAG------------------------------------------------------ 103 1,0 -----------------GUAAACAUCCUUGACUGGAAGa----------------------------------------------------- 24 1,0 -----------------GUAAACAUCCUUGACUGGAAGC----------------------------------------------------- 133 1,1 -----------------GUAAACAUCCUUGACUGGAAGCa---------------------------------------------------- 14 1,1 -----------------GUAAACAUCCUUGACUGGAAGCU---------------------------------------------------- 548 1,2 -----------------GUAAACAUCCUUGACUGGAAGCUu--------------------------------------------------- 15 1,2 -----------------GUAAACAUCCUUGACUGGAAGCUG--------------------------------------------------- 2 1,3 -----------------GUAAACAUCCUUGACUGGAAGCUGU-------------------------------------------------- 2 1,4 ------------------UAAACAUCCUUGACUGGAAGCU---------------------------------------------------- 5 2,2 ---------------------------------------------------------GCUUUCAGUCGGAUGUUUACAGu------------ 2 -1,-1 ----------------------------------------------------------CUUUCAGUCGGAUGUUUA---------------- 5 0,-4 ----------------------------------------------------------CUUUCAGUCGGAUGUUUAa--------------- 3 0,-4 ----------------------------------------------------------CUUUCAGUCGGAUGUUUAC--------------- 23 0,-3 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACA-------------- 253 0,-2 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAa------------- 10 0,-2 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAaa------------ 4 0,-2 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAuu------------ 10 0,-2 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAG------------- 193 0,-1 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGa------------ 103 0,-1 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGaa----------- 2 0,-1 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGg------------ 2 0,-1 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGu------------ 957 0,-1 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGuu----------- 53 0,-1 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGC------------ 371 0,0 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGCa----------- 39 0,0 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGCu----------- 5 0,0 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGCG----------- 2 0,1 -----------------------------------------------------------UUUCAGUCGGAUGUUUACA-------------- 2 1,-2 -----------------------------------------------------------UUUCAGUCGGAUGUUUACAG------------- 5 1,-1 -----------------------------------------------------------UUUCAGUCGGAUGUUUACAGa------------ 2 1,-1 -----------------------------------------------------------UUUCAGUCGGAUGUUUACAGu------------ 34 1,-1 -----------------------------------------------------------UUUCAGUCGGAUGUUUACAGuu----------- 4 1,-1 -----------------------------------------------------------UUUCAGUCGGAUGUUUACAGC------------ 8 1,0 >hsa-mir-31 MA:8-28;mi:44-65 Normal ggagaggAGGCAAGAUGCUGGCAUAGCUguugaacugggaaccUGCUAUGCCAACAUAUUGCCAUcuuucc -------AGGCAAGAUGCUGGCAUAG--------------------------------------------- 2 0,-2 -------AGGCAAGAUGCUGGCAUAGC-------------------------------------------- 2 0,-1 -------AGGCAAGAUGCUGGCAUAGCU------------------------------------------- 57 0,0 -------AGGCAAGAUGCUGGCAUAGCUa------------------------------------------ 2 0,0 -------AGGCAAGAUGCUGGCAUAGCUG------------------------------------------ 94 0,1 -------AGGCAAGAUGCUGGCAUAGCUGa----------------------------------------- 41 0,1 -------AGGCAAGAUGCUGGCAUAGCUGU----------------------------------------- 105 0,2 -------AGGCAAGAUGCUGGCAUAGCUGUU---------------------------------------- 2 0,3 --------GGCAAGAUGCUGGCAUAGCUGU----------------------------------------- 2 1,2 -------------------------------------------UGCUAUGCCAACAUAUUGCC-------- 2 0,-2 -------------------------------------------UGCUAUGCCAACAUAUUGCCA------- 3 0,-1 -------------------------------------------UGCUAUGCCAACAUAUUGCCAU------ 9 0,0 -------------------------------------------UGCUAUGCCAACAUAUUGCCAUa----- 2 0,0 -------------------------------------------UGCUAUGCCAACAUAUUGCCAUu----- 2 0,0 -------------------------------------------UGCUAUGCCAACAUAUUGCCAUC----- 16 0,1 >hsa-mir-3158-1 5p:13-33;3p:50-71 Normal auucaggccgguCCUGCAGAGAGGAAGCCCUUCugcuuacagguauuggAAGGGCUUCCUCUCUGCAGGACcggccugaau -------------------------------------------------AAGGGCUUCCUCUCUGCAGGA----------- 9 0,-1 -------------------------------------------------AAGGGCUUCCUCUCUGCAGGAC---------- 2 0,0 >hsa-mir-3158-2 3pM:50-71 Normal auucaggccgguccugcagagaggaagcccuuccaauaccuguaagcagAAGGGCUUCCUCUCUGCAGGACcggccugaau -------------------------------------------------AAGGGCUUCCUCUCUGCAGGA----------- 9 0,-1 -------------------------------------------------AAGGGCUUCCUCUCUGCAGGAC---------- 2 0,0 >hsa-mir-3159 5pM:10-31 Normal ccaaaguccUAGGAUUACAAGUGUCGGCCACgggcugggcacaguggcucacgccuguaaucccagcauuuugg ------------------------------------------------UCACGCCUGUAAUCCCAGCA------ 2 >hsa-mir-3173 5p:5-26;3p:43-64 Normal ucccUGCCCUGCCUGUUUUCUCCUUUgugauuuuaugagaacAAAGGAGGAAAUAGGCAGGCCAggga ----UGCCCUGCCUGUUUUCUCCUUU------------------------------------------ 2 0,0 >hsa-mir-32 MA:6-27;mi:47-68 Normal ggagaUAUUGCACAUUACUAAGUUGCAuguugucacggccucaaugCAAUUUAGUGUGUGUGAUAUUUuc -----UAUUGCACAUUACUAAGUU---------------------------------------------- 4 0,-3 -----UAUUGCACAUUACUAAGUUG--------------------------------------------- 54 0,-2 -----UAUUGCACAUUACUAAGUUGa-------------------------------------------- 4 0,-2 -----UAUUGCACAUUACUAAGUUGC-------------------------------------------- 55 0,-1 -----UAUUGCACAUUACUAAGUUGCA------------------------------------------- 44 0,0 -----UAUUGCACAUUACUAAGUUGCAU------------------------------------------ 2 0,1 ----------------------------------------------CAAUUUAGUGUGUGUGAUAUU--- 2 0,-1 >hsa-mir-3200 5p:13-34;3p:54-75 Normal gguggucgagggAAUCUGAGAAGGCGCACAAGGUuuguguccaauacaguccaCACCUUGCGCUACUCAGGUCUGcucgugcccu -----------------------------------------------------CACCUUGCGCUACUCAGGUCUGC--------- 2 0,1 >hsa-mir-320a 3pM:48-69 Normal gcuucgcuccccuccgccuucucuucccgguucuucccggagucgggAAAAGCUGGGUUGAGAGGGCGAaaaaggaugaggu ----------------------------------------------GAAAAGCUGGGUUGAGAG------------------ 11 -1,-5 ----------------------------------------------GAAAAGCUGGGUUGAGAGa----------------- 8 -1,-5 ----------------------------------------------GAAAAGCUGGGUUGAGAGaa---------------- 3 -1,-5 ----------------------------------------------GAAAAGCUGGGUUGAGAGG----------------- 24 -1,-4 ----------------------------------------------GAAAAGCUGGGUUGAGAGGG---------------- 21 -1,-3 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGa--------------- 10 -1,-3 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGau-------------- 2 -1,-3 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGC--------------- 19 -1,-2 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGCG-------------- 129 -1,-1 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGCGc------------- 5 -1,-1 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGCGg------------- 2 -1,-1 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGCGu------------- 73 -1,-1 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGCGuu------------ 2 -1,-1 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGCGA------------- 243 -1,0 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGCGAu------------ 12 -1,0 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGCGAA------------ 5 -1,1 -----------------------------------------------AAAAGCUGGGUUGAGAGG----------------- 312 0,-4 -----------------------------------------------AAAAGCUGGGUUGAGAGGu---------------- 13 0,-4 -----------------------------------------------AAAAGCUGGGUUGAGAGGG---------------- 603 0,-3 -----------------------------------------------AAAAGCUGGGUUGAGAGGGa--------------- 169 0,-3 -----------------------------------------------AAAAGCUGGGUUGAGAGGGaa-------------- 140 0,-3 -----------------------------------------------AAAAGCUGGGUUGAGAGGGau-------------- 46 0,-3 -----------------------------------------------AAAAGCUGGGUUGAGAGGGC--------------- 447 0,-2 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCu-------------- 14 0,-2 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCuu------------- 2 0,-2 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCG-------------- 2070 0,-1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGc------------- 190 0,-1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGg------------- 20 0,-1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGu------------- 1232 0,-1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGuu------------ 427 0,-1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGA------------- 17261 0,0 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAc------------ 70 0,0 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAg------------ 140 0,0 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAu------------ 5635 0,0 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAuu----------- 1026 0,0 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAA------------ 7115 0,1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAc----------- 54 0,1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAg----------- 255 0,1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAu----------- 2919 0,1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAuu---------- 73 0,1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAA----------- 2831 0,2 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAAc---------- 2 0,2 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAAg---------- 13 0,2 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAAu---------- 227 0,2 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAAA---------- 180 0,3 ------------------------------------------------AAAGCUGGGUUGAGAGGG---------------- 19 1,-3 ------------------------------------------------AAAGCUGGGUUGAGAGGGa--------------- 5 1,-3 ------------------------------------------------AAAGCUGGGUUGAGAGGGaa-------------- 11 1,-3 ------------------------------------------------AAAGCUGGGUUGAGAGGGau-------------- 4 1,-3 ------------------------------------------------AAAGCUGGGUUGAGAGGGC--------------- 16 1,-2 ------------------------------------------------AAAGCUGGGUUGAGAGGGCG-------------- 76 1,-1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGc------------- 4 1,-1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGu------------- 32 1,-1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGuu------------ 19 1,-1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGA------------- 744 1,0 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAc------------ 2 1,0 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAg------------ 3 1,0 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAu------------ 280 1,0 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAuu----------- 65 1,0 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAA------------ 442 1,1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAg----------- 25 1,1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAu----------- 324 1,1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAuu---------- 14 1,1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAA----------- 293 1,2 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAAg---------- 2 1,2 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAAu---------- 29 1,2 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAAA---------- 44 1,3 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAAAA--------- 2 1,4 -------------------------------------------------AAGCUGGGUUGAGAGGGCGA------------- 18 2,0 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAu------------ 8 2,0 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAuu----------- 2 2,0 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAA------------ 18 2,1 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAAu----------- 20 2,1 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAAA----------- 25 2,2 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAAAg---------- 3 2,2 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAAAu---------- 14 2,2 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAAAAg--------- 2 2,3 >hsa-mir-320b-1 3pM:39-60 Normal aauuaaucccucucuuucuaguucuuccuagagugaggAAAAGCUGGGUUGAGAGGGCAAacaaauuaacuaauuaauu -------------------------------------GAAAAGCUGGGUUGAGAG------------------------ 11 -1,-5 -------------------------------------GAAAAGCUGGGUUGAGAGa----------------------- 8 -1,-5 -------------------------------------GAAAAGCUGGGUUGAGAGaa---------------------- 3 -1,-5 -------------------------------------GAAAAGCUGGGUUGAGAGG----------------------- 24 -1,-4 -------------------------------------GAAAAGCUGGGUUGAGAGGG---------------------- 21 -1,-3 -------------------------------------GAAAAGCUGGGUUGAGAGGGa--------------------- 10 -1,-3 -------------------------------------GAAAAGCUGGGUUGAGAGGGau-------------------- 2 -1,-3 -------------------------------------GAAAAGCUGGGUUGAGAGGGC--------------------- 19 -1,-2 -------------------------------------GAAAAGCUGGGUUGAGAGGGCA-------------------- 2 -1,-1 -------------------------------------GAAAAGCUGGGUUGAGAGGGCAu------------------- 2 -1,-1 -------------------------------------GAAAAGCUGGGUUGAGAGGGCAA------------------- 7 -1,0 --------------------------------------AAAAGCUGGGUUGAGAGG----------------------- 312 0,-4 --------------------------------------AAAAGCUGGGUUGAGAGGu---------------------- 13 0,-4 --------------------------------------AAAAGCUGGGUUGAGAGGG---------------------- 603 0,-3 --------------------------------------AAAAGCUGGGUUGAGAGGGa--------------------- 169 0,-3 --------------------------------------AAAAGCUGGGUUGAGAGGGaa-------------------- 140 0,-3 --------------------------------------AAAAGCUGGGUUGAGAGGGau-------------------- 46 0,-3 --------------------------------------AAAAGCUGGGUUGAGAGGGC--------------------- 447 0,-2 --------------------------------------AAAAGCUGGGUUGAGAGGGCu-------------------- 14 0,-2 --------------------------------------AAAAGCUGGGUUGAGAGGGCuu------------------- 2 0,-2 --------------------------------------AAAAGCUGGGUUGAGAGGGCA-------------------- 51 0,-1 --------------------------------------AAAAGCUGGGUUGAGAGGGCAu------------------- 57 0,-1 --------------------------------------AAAAGCUGGGUUGAGAGGGCAuu------------------ 4 0,-1 --------------------------------------AAAAGCUGGGUUGAGAGGGCAA------------------- 140 0,0 --------------------------------------AAAAGCUGGGUUGAGAGGGCAAu------------------ 48 0,0 --------------------------------------AAAAGCUGGGUUGAGAGGGCAAuu----------------- 2 0,0 --------------------------------------AAAAGCUGGGUUGAGAGGGCAAA------------------ 58 0,1 --------------------------------------AAAAGCUGGGUUGAGAGGGCAAAu----------------- 11 0,1 ---------------------------------------AAAGCUGGGUUGAGAGGG---------------------- 19 1,-3 ---------------------------------------AAAGCUGGGUUGAGAGGGa--------------------- 5 1,-3 ---------------------------------------AAAGCUGGGUUGAGAGGGaa-------------------- 11 1,-3 ---------------------------------------AAAGCUGGGUUGAGAGGGau-------------------- 4 1,-3 ---------------------------------------AAAGCUGGGUUGAGAGGGC--------------------- 16 1,-2 ---------------------------------------AAAGCUGGGUUGAGAGGGCAA------------------- 2 1,0 >hsa-mir-320b-2 3pM:72-93 Normal uguuauuuuuugucuucuaccuaagaauucugucucuuaggcuuucucuucccagauuucccaaaguugggAAAAGCUGGGUUGAGAGGGCAAaaggaaaaaaaaagaauucugucucugacauaauuagauagggaa ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAG-------------------------------------------------- 11 -1,-5 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGa------------------------------------------------- 8 -1,-5 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGaa------------------------------------------------ 3 -1,-5 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGG------------------------------------------------- 24 -1,-4 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGGG------------------------------------------------ 21 -1,-3 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGGGa----------------------------------------------- 10 -1,-3 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGGGau---------------------------------------------- 2 -1,-3 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGGGC----------------------------------------------- 19 -1,-2 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGGGCA---------------------------------------------- 2 -1,-1 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGGGCAu--------------------------------------------- 2 -1,-1 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGGGCAA--------------------------------------------- 7 -1,0 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGG------------------------------------------------- 312 0,-4 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGu------------------------------------------------ 13 0,-4 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGG------------------------------------------------ 603 0,-3 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGa----------------------------------------------- 169 0,-3 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGaa---------------------------------------------- 140 0,-3 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGau---------------------------------------------- 46 0,-3 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGC----------------------------------------------- 447 0,-2 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCu---------------------------------------------- 14 0,-2 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCuu--------------------------------------------- 2 0,-2 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCA---------------------------------------------- 51 0,-1 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAu--------------------------------------------- 57 0,-1 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAuu-------------------------------------------- 4 0,-1 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAA--------------------------------------------- 140 0,0 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAAu-------------------------------------------- 48 0,0 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAAuu------------------------------------------- 2 0,0 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAAA-------------------------------------------- 58 0,1 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAAAu------------------------------------------- 11 0,1 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAAAA------------------------------------------- 12 0,2 ------------------------------------------------------------------------AAAGCUGGGUUGAGAGGG------------------------------------------------ 19 1,-3 ------------------------------------------------------------------------AAAGCUGGGUUGAGAGGGa----------------------------------------------- 5 1,-3 ------------------------------------------------------------------------AAAGCUGGGUUGAGAGGGaa---------------------------------------------- 11 1,-3 ------------------------------------------------------------------------AAAGCUGGGUUGAGAGGGau---------------------------------------------- 4 1,-3 ------------------------------------------------------------------------AAAGCUGGGUUGAGAGGGC----------------------------------------------- 16 1,-2 ------------------------------------------------------------------------AAAGCUGGGUUGAGAGGGCAA--------------------------------------------- 2 1,0 >hsa-mir-320c-1 3pM:50-69 Normal uuugcauuaaaaaugaggccuucucuucccaguucuucccagagucaggAAAAGCUGGGUUGAGAGGGUagaaaaaaaaugauguagg ------------------------------------------------GAAAAGCUGGGUUGAGAG---------------------- 11 -1,-3 ------------------------------------------------GAAAAGCUGGGUUGAGAGa--------------------- 8 -1,-3 ------------------------------------------------GAAAAGCUGGGUUGAGAGaa-------------------- 3 -1,-3 ------------------------------------------------GAAAAGCUGGGUUGAGAGG--------------------- 24 -1,-2 ------------------------------------------------GAAAAGCUGGGUUGAGAGGG-------------------- 21 -1,-1 ------------------------------------------------GAAAAGCUGGGUUGAGAGGGa------------------- 10 -1,-1 ------------------------------------------------GAAAAGCUGGGUUGAGAGGGau------------------ 2 -1,-1 ------------------------------------------------GAAAAGCUGGGUUGAGAGGGUA------------------ 2 -1,1 -------------------------------------------------AAAAGCUGGGUUGAGAGG--------------------- 312 0,-2 -------------------------------------------------AAAAGCUGGGUUGAGAGGu-------------------- 13 0,-2 -------------------------------------------------AAAAGCUGGGUUGAGAGGG-------------------- 603 0,-1 -------------------------------------------------AAAAGCUGGGUUGAGAGGGa------------------- 169 0,-1 -------------------------------------------------AAAAGCUGGGUUGAGAGGGaa------------------ 140 0,-1 -------------------------------------------------AAAAGCUGGGUUGAGAGGGau------------------ 46 0,-1 -------------------------------------------------AAAAGCUGGGUUGAGAGGGU------------------- 91 0,0 -------------------------------------------------AAAAGCUGGGUUGAGAGGGUu------------------ 2 0,0 -------------------------------------------------AAAAGCUGGGUUGAGAGGGUuu----------------- 5 0,0 -------------------------------------------------AAAAGCUGGGUUGAGAGGGUA------------------ 2 0,1 -------------------------------------------------AAAAGCUGGGUUGAGAGGGUAa----------------- 4 0,1 -------------------------------------------------AAAAGCUGGGUUGAGAGGGUAaa---------------- 2 0,1 --------------------------------------------------AAAGCUGGGUUGAGAGGG-------------------- 19 1,-1 --------------------------------------------------AAAGCUGGGUUGAGAGGGa------------------- 5 1,-1 --------------------------------------------------AAAGCUGGGUUGAGAGGGaa------------------ 11 1,-1 --------------------------------------------------AAAGCUGGGUUGAGAGGGau------------------ 4 1,-1 --------------------------------------------------AAAGCUGGGUUGAGAGGGU------------------- 2 1,0 --------------------------------------------------AAAGCUGGGUUGAGAGGGUAa----------------- 2 1,1 >hsa-mir-320c-2 3pM:31-50 Normal cuucucuuuccaguucuucccagaauugggAAAAGCUGGGUUGAGAGGGU -----------------------------GAAAAGCUGGGUUGAGAG--- 11 -1,-3 -----------------------------GAAAAGCUGGGUUGAGAGa-- 8 -1,-3 -----------------------------GAAAAGCUGGGUUGAGAGaa- 3 -1,-3 -----------------------------GAAAAGCUGGGUUGAGAGG-- 24 -1,-2 -----------------------------GAAAAGCUGGGUUGAGAGGG- 21 -1,-1 -----------------------------GAAAAGCUGGGUUGAGAGGGa 10 -1,-1 -----------------------------GAAAAGCUGGGUUGAGAGGGau 2 -1,-1 ------------------------------AAAAGCUGGGUUGAGAGG-- 312 0,-2 ------------------------------AAAAGCUGGGUUGAGAGGu- 13 0,-2 ------------------------------AAAAGCUGGGUUGAGAGGG- 603 0,-1 ------------------------------AAAAGCUGGGUUGAGAGGGa 169 0,-1 ------------------------------AAAAGCUGGGUUGAGAGGGaa 140 0,-1 ------------------------------AAAAGCUGGGUUGAGAGGGau 46 0,-1 ------------------------------AAAAGCUGGGUUGAGAGGGU 91 0,0 ------------------------------AAAAGCUGGGUUGAGAGGGUu 2 0,0 ------------------------------AAAAGCUGGGUUGAGAGGGUuu 5 0,0 -------------------------------AAAGCUGGGUUGAGAGGG- 19 1,-1 -------------------------------AAAGCUGGGUUGAGAGGGa 5 1,-1 -------------------------------AAAGCUGGGUUGAGAGGGaa 11 1,-1 -------------------------------AAAGCUGGGUUGAGAGGGau 4 1,-1 -------------------------------AAAGCUGGGUUGAGAGGGU 2 1,0 >hsa-mir-320d-1 3pM:30-48 Normal uucucgucccaguucuucccaaaguugagAAAAGCUGGGUUGAGAGGA ----------------------------GAAAAGCUGGGUUGAGAG-- 11 -1,-2 ----------------------------GAAAAGCUGGGUUGAGAGa- 8 -1,-2 ----------------------------GAAAAGCUGGGUUGAGAGaa 3 -1,-2 ----------------------------GAAAAGCUGGGUUGAGAGG- 24 -1,-1 -----------------------------AAAAGCUGGGUUGAGAGG- 312 0,-1 -----------------------------AAAAGCUGGGUUGAGAGGu 13 0,-1 -----------------------------AAAAGCUGGGUUGAGAGGA 335 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAa 121 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAaa 190 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAau 63 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAu 26 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAuu 2 0,0 ------------------------------AAAGCUGGGUUGAGAGGA 9 1,0 ------------------------------AAAGCUGGGUUGAGAGGAa 9 1,0 ------------------------------AAAGCUGGGUUGAGAGGAaa 14 1,0 ------------------------------AAAGCUGGGUUGAGAGGAu 2 1,0 >hsa-mir-320d-2 3pM:30-48 Normal uucucuucccaguucuucuuggagucaggAAAAGCUGGGUUGAGAGGA ----------------------------GAAAAGCUGGGUUGAGAG-- 11 -1,-2 ----------------------------GAAAAGCUGGGUUGAGAGa- 8 -1,-2 ----------------------------GAAAAGCUGGGUUGAGAGaa 3 -1,-2 ----------------------------GAAAAGCUGGGUUGAGAGG- 24 -1,-1 -----------------------------AAAAGCUGGGUUGAGAGG- 312 0,-1 -----------------------------AAAAGCUGGGUUGAGAGGu 13 0,-1 -----------------------------AAAAGCUGGGUUGAGAGGA 335 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAa 121 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAaa 190 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAau 63 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAu 26 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAuu 2 0,0 ------------------------------AAAGCUGGGUUGAGAGGA 9 1,0 ------------------------------AAAGCUGGGUUGAGAGGAa 9 1,0 ------------------------------AAAGCUGGGUUGAGAGGAaa 14 1,0 ------------------------------AAAGCUGGGUUGAGAGGAu 2 1,0 >hsa-mir-320e 3pM:35-52 Normal gccuucucuucccaguucuuccuggagucggggaAAAGCUGGGUUGAGAAGGu --------------------------------GAAAAGCUGGGUUGAGAAa-- 5 -2,-2 ---------------------------------AAAAGCUGGGUUGAGAAGG- 93 -1,0 ----------------------------------AAAGCUGGGUUGAGAAGG- 3 0,0 >hsa-mir-323 5p:16-37;3p:51-71 Normal uugguacuuggagagAGGUGGUCCGUGGCGCGUUCGCuuuauuuauggcgCACAUUACACGGUCGACCUCUuugcaguaucuaauc -------------------------------------------------GCACAUUACACGGUCGACCUCU--------------- 13 -1,0 --------------------------------------------------CACAUUACACGGUCGACCUCU--------------- 12 0,0 >hsa-mir-324 5p:16-38;3p:53-72 Normal cugacuaugccucccCGCAUCCCCUAGGGCAUUGGUGUaaagcuggagacccACUGCCCCAGGUGCUGCUGGggguuguaguc ---------------CGCAUCCCCUAGGGCAUUG------------------------------------------------- 2 0,-4 ---------------CGCAUCCCCUAGGGCAUUGG------------------------------------------------ 3 0,-3 ---------------CGCAUCCCCUAGGGCAUUGGa----------------------------------------------- 3 0,-3 ---------------CGCAUCCCCUAGGGCAUUGGaa---------------------------------------------- 3 0,-3 ---------------CGCAUCCCCUAGGGCAUUGGU----------------------------------------------- 58 0,-2 ---------------CGCAUCCCCUAGGGCAUUGGUaa--------------------------------------------- 2 0,-2 ---------------CGCAUCCCCUAGGGCAUUGGUG---------------------------------------------- 78 0,-1 ---------------CGCAUCCCCUAGGGCAUUGGUGa--------------------------------------------- 47 0,-1 ---------------CGCAUCCCCUAGGGCAUUGGUGau-------------------------------------------- 2 0,-1 ---------------CGCAUCCCCUAGGGCAUUGGUGU--------------------------------------------- 429 0,0 ---------------CGCAUCCCCUAGGGCAUUGGUGUu-------------------------------------------- 9 0,0 ----------------GCAUCCCCUAGGGCAUUGGU----------------------------------------------- 2 1,-2 ----------------GCAUCCCCUAGGGCAUUGGUGU--------------------------------------------- 12 1,0 --------------------------------------------------CCACUGCCCCAGGUGCUGCU------------- 3 -2,-2 --------------------------------------------------CCACUGCCCCAGGUGCUGCUG------------ 6 -2,-1 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGa----------- 2 -2,-1 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGu----------- 7 -2,-1 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGG----------- 41 -2,0 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGGa---------- 6 -2,0 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGGaa--------- 8 -2,0 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGGau--------- 5 -2,0 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGGu---------- 6 -2,0 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGGuu--------- 4 -2,0 ---------------------------------------------------CACUGCCCCAGGUGCUGCUGG----------- 3 -1,0 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGa----------- 2 0,-1 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGu----------- 2 0,-1 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGG----------- 253 0,0 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGGa---------- 56 0,0 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGGaa--------- 70 0,0 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGGau--------- 16 0,0 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGGu---------- 329 0,0 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGGuu--------- 131 0,0 -----------------------------------------------------CUGCCCCAGGUGCUGCUGGu---------- 2 1,0 >hsa-mir-326 3pM:60-79 Normal cucaucugucuguugggcuggaggcagggccuuugugaaggcggguggugcucagaucgCCUCUGGGCCCUUCCUCCAGccccgaggcggauuca -----------------------------------------------------------CCUCUGGGCCCUUCCUCC------------------ 13 0,-2 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCA----------------- 6 0,-1 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAau--------------- 3 0,-1 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAuu--------------- 5 0,-1 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAG---------------- 12 0,0 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAGa--------------- 32 0,0 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAGaa-------------- 2 0,0 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAGu--------------- 219 0,0 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAGuu-------------- 40 0,0 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAGC--------------- 6 0,1 ------------------------------------------------------------CUCUGGGCCCUUCCUCCAGu--------------- 6 1,0 ------------------------------------------------------------CUCUGGGCCCUUCCUCCAGuu-------------- 2 1,0 >hsa-mir-328 3pM:48-69 Normal uggagugggggggcaggaggggcucagggagaaagugcauacagcccCUGGCCCUCUCUGCCCUUCCGUccccug -----------------------------------------------CUGGCCCUCUCUGCCCUUC--------- 2 0,-3 -----------------------------------------------CUGGCCCUCUCUGCCCUUCC-------- 8 0,-2 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCG------- 43 0,-1 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGa------ 72 0,-1 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGaa----- 5 0,-1 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGau----- 5 0,-1 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGc------ 5 0,-1 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGU------ 436 0,0 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGUa----- 19 0,0 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGUaa---- 9 0,0 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGUau---- 8 0,0 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGUu----- 177 0,0 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGUuu---- 57 0,0 ------------------------------------------------UGGCCCUCUCUGCCCUUCCGa------ 4 1,-1 ------------------------------------------------UGGCCCUCUCUGCCCUUCCGU------ 20 1,0 ------------------------------------------------UGGCCCUCUCUGCCCUUCCGUu----- 12 1,0 ------------------------------------------------UGGCCCUCUCUGCCCUUCCGUuu---- 2 1,0 >hsa-mir-329-1 3pM:50-71 Normal gguaccugaagagagguuuucuggguuucuguuucuuuaaugaggacgaAACACACCUGGUUAACCUCUUUuccaguauc -------------------------------------------------AACACACCUGGUUAACCUCU----------- 16 0,-2 -------------------------------------------------AACACACCUGGUUAACCUCUaa--------- 2 0,-2 -------------------------------------------------AACACACCUGGUUAACCUCUau--------- 2 0,-2 -------------------------------------------------AACACACCUGGUUAACCUCUU---------- 18 0,-1 -------------------------------------------------AACACACCUGGUUAACCUCUUa--------- 4 0,-1 -------------------------------------------------AACACACCUGGUUAACCUCUUU--------- 24 0,0 --------------------------------------------------ACACACCUGGUUAACCUCUUau-------- 2 1,-1 --------------------------------------------------ACACACCUGGUUAACCUCUUU--------- 5 1,0 >hsa-mir-329-2 3pM:52-73 Normal gugguaccugaagagagguuuucuggguuucuguuucuuuauugaggacgaAACACACCUGGUUAACCUCUUUuccaguaucaa ---------------------------------------------------AACACACCUGGUUAACCUCU------------- 16 0,-2 ---------------------------------------------------AACACACCUGGUUAACCUCUaa----------- 2 0,-2 ---------------------------------------------------AACACACCUGGUUAACCUCUau----------- 2 0,-2 ---------------------------------------------------AACACACCUGGUUAACCUCUU------------ 18 0,-1 ---------------------------------------------------AACACACCUGGUUAACCUCUUa----------- 4 0,-1 ---------------------------------------------------AACACACCUGGUUAACCUCUUU----------- 24 0,0 ----------------------------------------------------ACACACCUGGUUAACCUCUUau---------- 2 1,-1 ----------------------------------------------------ACACACCUGGUUAACCUCUUU----------- 5 1,0 >hsa-mir-330 5p:18-39;3p:57-79 Normal cuuuggcgaucacugccUCUCUGGGCCUGUGUCUUAGGCucugcaagaucaaccgaGCAAAGCACACGGCCUGCAGAGAggcagcgcucugccc --------------------------------------------------------GCAAAGCACACGGCCUGCAGA----------------- 6 0,-2 --------------------------------------------------------GCAAAGCACACGGCCUGCAGAG---------------- 2 0,-1 --------------------------------------------------------GCAAAGCACACGGCCUGCAGAGu--------------- 2 0,-1 --------------------------------------------------------GCAAAGCACACGGCCUGCAGAGA--------------- 16 0,0 ---------------------------------------------------------CAAAGCACACGGCCUGCAGAGA--------------- 5 1,0 >hsa-mir-331 5p:26-47;3p:61-81 Normal gaguuugguuuuguuuggguuuguuCUAGGUAUGGUCCCAGGGAUCCcagaucaaaccagGCCCCUGGGCCUAUCCUAGAAccaaccuaagcuc ------------------------------------------------------------GCCCCUGGGCCUAUCCUA---------------- 4 0,-3 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAG--------------- 19 0,-2 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGc-------------- 2 0,-2 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGA-------------- 317 0,-1 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAc------------- 32 0,-1 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAu------------- 17 0,-1 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAuu------------ 8 0,-1 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAA------------- 274 0,0 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAAa------------ 234 0,0 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAAaa----------- 36 0,0 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAAg------------ 4 0,0 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAAu------------ 258 0,0 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAAuu----------- 8 0,0 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAAC------------ 5 0,1 -------------------------------------------------------------CCCCUGGGCCUAUCCUAGA-------------- 11 1,-1 -------------------------------------------------------------CCCCUGGGCCUAUCCUAGAc------------- 5 1,-1 -------------------------------------------------------------CCCCUGGGCCUAUCCUAGAA------------- 10 1,0 -------------------------------------------------------------CCCCUGGGCCUAUCCUAGAAa------------ 7 1,0 -------------------------------------------------------------CCCCUGGGCCUAUCCUAGAAu------------ 30 1,0 >hsa-mir-335 MA:16-38;mi:52-73 Normal uguuuugagcgggggUCAAGAGCAAUAACGAAAAAUGUuugucauaaaccgUUUUUCAUUAUUGCUCCUGACCuccucucauuugcuauauuca ---------------UCAAGAGCAAUAACGAAA------------------------------------------------------------- 18 0,-5 ---------------UCAAGAGCAAUAACGAAAA------------------------------------------------------------ 17 0,-4 ---------------UCAAGAGCAAUAACGAAAAA----------------------------------------------------------- 41 0,-3 ---------------UCAAGAGCAAUAACGAAAAAa---------------------------------------------------------- 13 0,-3 ---------------UCAAGAGCAAUAACGAAAAAaa--------------------------------------------------------- 2 0,-3 ---------------UCAAGAGCAAUAACGAAAAAU---------------------------------------------------------- 474 0,-2 ---------------UCAAGAGCAAUAACGAAAAAUa--------------------------------------------------------- 5 0,-2 ---------------UCAAGAGCAAUAACGAAAAAUG--------------------------------------------------------- 1394 0,-1 ---------------UCAAGAGCAAUAACGAAAAAUGa-------------------------------------------------------- 145 0,-1 ---------------UCAAGAGCAAUAACGAAAAAUGU-------------------------------------------------------- 860 0,0 ---------------UCAAGAGCAAUAACGAAAAAUGUU------------------------------------------------------- 7 0,1 ----------------CAAGAGCAAUAACGAAAAAa---------------------------------------------------------- 2 1,-3 ----------------CAAGAGCAAUAACGAAAAAU---------------------------------------------------------- 17 1,-2 ----------------CAAGAGCAAUAACGAAAAAUG--------------------------------------------------------- 19 1,-1 ----------------CAAGAGCAAUAACGAAAAAUGa-------------------------------------------------------- 2 1,-1 ----------------CAAGAGCAAUAACGAAAAAUGU-------------------------------------------------------- 26 1,0 -----------------AAGAGCAAUAACGAAAAAU---------------------------------------------------------- 7 2,-2 -----------------AAGAGCAAUAACGAAAAAUG--------------------------------------------------------- 15 2,-1 -----------------AAGAGCAAUAACGAAAAAUGU-------------------------------------------------------- 8 2,0 --------------------------------------------------GUUUUUCAUUAUUGCUCCUGAC---------------------- 2 -1,-1 --------------------------------------------------GUUUUUCAUUAUUGCUCCUGACa--------------------- 2 -1,-1 --------------------------------------------------GUUUUUCAUUAUUGCUCCUGACu--------------------- 4 -1,-1 --------------------------------------------------GUUUUUCAUUAUUGCUCCUGACC--------------------- 30 -1,0 ---------------------------------------------------UUUUUCAUUAUUGCUCCU------------------------- 4 0,-4 ---------------------------------------------------UUUUUCAUUAUUGCUCCUGA----------------------- 7 0,-2 ---------------------------------------------------UUUUUCAUUAUUGCUCCUGAC---------------------- 16 0,-1 ---------------------------------------------------UUUUUCAUUAUUGCUCCUGACa--------------------- 2 0,-1 ---------------------------------------------------UUUUUCAUUAUUGCUCCUGACu--------------------- 7 0,-1 ---------------------------------------------------UUUUUCAUUAUUGCUCCUGACC--------------------- 72 0,0 >hsa-mir-337 5p:23-43;3p:61-82 Normal guagucaguaguugggggguggGAACGGCUUCAUACAGGAGUUgaugcacaguuauccagCUCCUAUAUGAUGCCUUUCUUCauccccuucaa ----------------------GAACGGCUUCAUACAGGAGU--------------------------------------------------- 2 0,-1 -----------------------AACGGCUUCAUACAGGAGUUGA------------------------------------------------ 2 1,2 ------------------------------------------------------------CUCCUAUAUGAUGCCUUUCU------------- 3 0,-2 ------------------------------------------------------------CUCCUAUAUGAUGCCUUUCUU------------ 17 0,-1 ------------------------------------------------------------CUCCUAUAUGAUGCCUUUCUUC----------- 18 0,0 -------------------------------------------------------------UCCUAUAUGAUGCCUUUCUU------------ 8 1,-1 -------------------------------------------------------------UCCUAUAUGAUGCCUUUCUUC----------- 32 1,0 >hsa-mir-338 5p:6-27;3p:42-63 Normal ucuccAACAAUAUCCUGGUGCUGAGUGaugacucaggcgacUCCAGCAUCAGUGAUUUUGUUGaaga -----AACAAUAUCCUGGUGCUGAGU----------------------------------------- 13 0,-1 -----------------------------------------UCCAGCAUCAGUGAUUUUGU------ 3 0,-2 -----------------------------------------UCCAGCAUCAGUGAUUUUGUU----- 14 0,-1 -----------------------------------------UCCAGCAUCAGUGAUUUUGUUG---- 5 0,0 -----------------------------------------UCCAGCAUCAGUGAUUUUGUUGA--- 36 0,1 >hsa-mir-339 5p:15-37;3p:50-72 Normal cggggcggccgcucUCCCUGUCCUCCAGGAGCUCACGugugccugccugUGAGCGCCUCGACGACAGAGCCGgcgccugccccagugucugcgc --------------UCCCUGUCCUCCAGGAGC-------------------------------------------------------------- 2 0,-5 --------------UCCCUGUCCUCCAGGAGCU------------------------------------------------------------- 58 0,-4 --------------UCCCUGUCCUCCAGGAGCUa------------------------------------------------------------ 2 0,-4 --------------UCCCUGUCCUCCAGGAGCUu------------------------------------------------------------ 4 0,-4 --------------UCCCUGUCCUCCAGGAGCUC------------------------------------------------------------ 68 0,-3 --------------UCCCUGUCCUCCAGGAGCUCc----------------------------------------------------------- 2 0,-3 --------------UCCCUGUCCUCCAGGAGCUCu----------------------------------------------------------- 4 0,-3 --------------UCCCUGUCCUCCAGGAGCUCA----------------------------------------------------------- 184 0,-2 --------------UCCCUGUCCUCCAGGAGCUCAa---------------------------------------------------------- 23 0,-2 --------------UCCCUGUCCUCCAGGAGCUCAaa--------------------------------------------------------- 4 0,-2 --------------UCCCUGUCCUCCAGGAGCUCAau--------------------------------------------------------- 6 0,-2 --------------UCCCUGUCCUCCAGGAGCUCAu---------------------------------------------------------- 12 0,-2 --------------UCCCUGUCCUCCAGGAGCUCAuu--------------------------------------------------------- 4 0,-2 --------------UCCCUGUCCUCCAGGAGCUCAC---------------------------------------------------------- 33 0,-1 --------------UCCCUGUCCUCCAGGAGCUCACa--------------------------------------------------------- 8 0,-1 --------------UCCCUGUCCUCCAGGAGCUCACu--------------------------------------------------------- 4 0,-1 --------------UCCCUGUCCUCCAGGAGCUCACG--------------------------------------------------------- 162 0,0 --------------UCCCUGUCCUCCAGGAGCUCACGa-------------------------------------------------------- 9 0,0 --------------UCCCUGUCCUCCAGGAGCUCACGU-------------------------------------------------------- 8 0,1 ----------------CCUGUCCUCCAGGAGCUC------------------------------------------------------------ 2 2,-3 ----------------CCUGUCCUCCAGGAGCUCACG--------------------------------------------------------- 2 2,0 -------------------------------------------------UGAGCGCCUCGACGACAG--------------------------- 2 0,-5 -------------------------------------------------UGAGCGCCUCGACGACAGA-------------------------- 17 0,-4 -------------------------------------------------UGAGCGCCUCGACGACAGAG------------------------- 77 0,-3 -------------------------------------------------UGAGCGCCUCGACGACAGAGa------------------------ 15 0,-3 -------------------------------------------------UGAGCGCCUCGACGACAGAGC------------------------ 175 0,-2 -------------------------------------------------UGAGCGCCUCGACGACAGAGCa----------------------- 9 0,-2 -------------------------------------------------UGAGCGCCUCGACGACAGAGCau---------------------- 2 0,-2 -------------------------------------------------UGAGCGCCUCGACGACAGAGCu----------------------- 5 0,-2 -------------------------------------------------UGAGCGCCUCGACGACAGAGCC----------------------- 37 0,-1 -------------------------------------------------UGAGCGCCUCGACGACAGAGCCa---------------------- 18 0,-1 -------------------------------------------------UGAGCGCCUCGACGACAGAGCCu---------------------- 18 0,-1 -------------------------------------------------UGAGCGCCUCGACGACAGAGCCuu--------------------- 3 0,-1 -------------------------------------------------UGAGCGCCUCGACGACAGAGCCG---------------------- 106 0,0 -------------------------------------------------UGAGCGCCUCGACGACAGAGCCGa--------------------- 12 0,0 -------------------------------------------------UGAGCGCCUCGACGACAGAGCCGu--------------------- 18 0,0 --------------------------------------------------GAGCGCCUCGACGACAGAGC------------------------ 4 1,-2 --------------------------------------------------GAGCGCCUCGACGACAGAGCCG---------------------- 16 1,0 --------------------------------------------------GAGCGCCUCGACGACAGAGCCGa--------------------- 2 1,0 ---------------------------------------------------AGCGCCUCGACGACAGAGCCu---------------------- 2 2,-1 ---------------------------------------------------AGCGCCUCGACGACAGAGCCG---------------------- 53 2,0 ---------------------------------------------------AGCGCCUCGACGACAGAGCCGa--------------------- 7 2,0 ---------------------------------------------------AGCGCCUCGACGACAGAGCCGu--------------------- 8 2,0 >hsa-mir-33a MA:6-26;mi:46-67 Normal cugugGUGCAUUGUAGUUGCAUUGCAuguucuggugguacccaugCAAUGUUUCCACAGUGCAUCACag -----GUGCAUUGUAGUUGCAUU---------------------------------------------- 3 0,-3 -----GUGCAUUGUAGUUGCAUUG--------------------------------------------- 6 0,-2 -----GUGCAUUGUAGUUGCAUUGa-------------------------------------------- 15 0,-2 -----GUGCAUUGUAGUUGCAUUGu-------------------------------------------- 4 0,-2 -----GUGCAUUGUAGUUGCAUUGC-------------------------------------------- 407 0,-1 -----GUGCAUUGUAGUUGCAUUGCA------------------------------------------- 210 0,0 -----GUGCAUUGUAGUUGCAUUGCAa------------------------------------------ 57 0,0 -----GUGCAUUGUAGUUGCAUUGCAaa----------------------------------------- 4 0,0 -----GUGCAUUGUAGUUGCAUUGCAau----------------------------------------- 3 0,0 -----GUGCAUUGUAGUUGCAUUGCAg------------------------------------------ 2 0,0 -----GUGCAUUGUAGUUGCAUUGCAU------------------------------------------ 5 0,1 ---------------------------------------------CAAUGUUUCCACAGUGCAUC---- 2 0,-2 ---------------------------------------------CAAUGUUUCCACAGUGCAUCA--- 9 0,-1 >hsa-mir-33b MA:16-35;mi:54-75 Normal gcgggcggccccgcgGUGCAUUGCUGUUGCAUUGCacgugugugaggcgggugCAGUGCCUCGGCAGUGCAGCCCggagccggccccuggcaccac ---------------GUGCAUUGCUGUUGCAUU--------------------------------------------------------------- 4 0,-2 ---------------GUGCAUUGCUGUUGCAUUu-------------------------------------------------------------- 2 0,-2 ---------------GUGCAUUGCUGUUGCAUUG-------------------------------------------------------------- 86 0,-1 ---------------GUGCAUUGCUGUUGCAUUGa------------------------------------------------------------- 78 0,-1 ---------------GUGCAUUGCUGUUGCAUUGg------------------------------------------------------------- 2 0,-1 ---------------GUGCAUUGCUGUUGCAUUGu------------------------------------------------------------- 15 0,-1 ---------------GUGCAUUGCUGUUGCAUUGC------------------------------------------------------------- 180 0,0 ---------------GUGCAUUGCUGUUGCAUUGCc------------------------------------------------------------ 2 0,0 ---------------GUGCAUUGCUGUUGCAUUGCu------------------------------------------------------------ 4 0,0 ---------------GUGCAUUGCUGUUGCAUUGCA------------------------------------------------------------ 116 0,1 ---------------GUGCAUUGCUGUUGCAUUGCAa----------------------------------------------------------- 31 0,1 ---------------GUGCAUUGCUGUUGCAUUGCAaa---------------------------------------------------------- 7 0,1 >hsa-mir-340 MA:16-37;mi:58-79 Normal uuguaccuggugugaUUAUAAAGCAAUGAGACUGAUUgucauaugucguuugugggaUCCGUCUCAGUUACUUUAUAGCcauaccugguaucuua ---------------UUAUAAAGCAAUGAGACUGA------------------------------------------------------------ 6 0,-2 ---------------UUAUAAAGCAAUGAGACUGAU----------------------------------------------------------- 16 0,-1 ---------------UUAUAAAGCAAUGAGACUGAUU---------------------------------------------------------- 41 0,0 ---------------UUAUAAAGCAAUGAGACUGAUUa--------------------------------------------------------- 2 0,0 ---------------------------------------------------------UCCGUCUCAGUUACUUUAUAGC---------------- 2 0,0 >hsa-mir-342 5p:19-39;3p:61-83 Normal gaaacugggcucaaggugAGGGGUGCUAUCUGUGAUUGAgggacaugguuaauggaauugUCUCACACAGAAAUCGCACCCGUcaccuuggccuacuua ------------------AGGGGUGCUAUCUGUGAUU-------------------------------------------------------------- 2 0,-2 ------------------AGGGGUGCUAUCUGUGAUUGA------------------------------------------------------------ 23 0,0 ------------------AGGGGUGCUAUCUGUGAUUGAa----------------------------------------------------------- 2 0,0 ------------------AGGGGUGCUAUCUGUGAUUGAG----------------------------------------------------------- 45 0,1 ------------------AGGGGUGCUAUCUGUGAUUGAGa---------------------------------------------------------- 29 0,1 ------------------AGGGGUGCUAUCUGUGAUUGAGG---------------------------------------------------------- 50 0,2 ------------------AGGGGUGCUAUCUGUGAUUGAGGu--------------------------------------------------------- 2 0,2 ------------------AGGGGUGCUAUCUGUGAUUGAGGG--------------------------------------------------------- 4 0,3 ------------------AGGGGUGCUAUCUGUGAUUGAGGGA-------------------------------------------------------- 2 0,4 -------------------GGGGUGCUAUCUGUGAUUGA------------------------------------------------------------ 6 1,0 -------------------GGGGUGCUAUCUGUGAUUGAG----------------------------------------------------------- 9 1,1 -------------------GGGGUGCUAUCUGUGAUUGAGa---------------------------------------------------------- 2 1,1 -------------------GGGGUGCUAUCUGUGAUUGAGG---------------------------------------------------------- 12 1,2 -------------------GGGGUGCUAUCUGUGAUUGAGGa--------------------------------------------------------- 2 1,2 -------------------GGGGUGCUAUCUGUGAUUGAGGG--------------------------------------------------------- 7 1,3 -------------------GGGGUGCUAUCUGUGAUUGAGGGu-------------------------------------------------------- 2 1,3 -------------------GGGGUGCUAUCUGUGAUUGAGGGA-------------------------------------------------------- 5 1,4 -------------------GGGGUGCUAUCUGUGAUUGAGGGAu------------------------------------------------------- 2 1,4 -------------------GGGGUGCUAUCUGUGAUUGAGGGAC------------------------------------------------------- 13 1,5 ------------------------------------------------------------UCUCACACAGAAAUCGCA--------------------- 4 0,-5 ------------------------------------------------------------UCUCACACAGAAAUCGCACC------------------- 2 0,-3 ------------------------------------------------------------UCUCACACAGAAAUCGCACCC------------------ 2 0,-2 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCG----------------- 98 0,-1 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGa---------------- 6 0,-1 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGc---------------- 2 0,-1 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGU---------------- 542 0,0 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGUu--------------- 16 0,0 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGUC--------------- 208 0,1 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGUCu-------------- 29 0,1 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGUCA-------------- 8 0,2 -------------------------------------------------------------CUCACACAGAAAUCGCACCCGU---------------- 18 1,0 -------------------------------------------------------------CUCACACAGAAAUCGCACCCGUC--------------- 2 1,1 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUC--------------- 6 2,1 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUCu-------------- 6 2,1 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUCA-------------- 27 2,2 >hsa-mir-345 5pM:18-39 Normal acccaaacccuaggucuGCUGACUCCUAGUCCAGGGCUCgugauggcuggugggcccugaacgaggggucuggaggccuggguuugaauaucgacagc -----------------GCUGACUCCUAGUCCAGG--------------------------------------------------------------- 3 0,-4 -----------------GCUGACUCCUAGUCCAGGaa------------------------------------------------------------- 2 0,-4 -----------------GCUGACUCCUAGUCCAGGG-------------------------------------------------------------- 8 0,-3 -----------------GCUGACUCCUAGUCCAGGGa------------------------------------------------------------- 5 0,-3 -----------------GCUGACUCCUAGUCCAGGGaa------------------------------------------------------------ 7 0,-3 -----------------GCUGACUCCUAGUCCAGGGC------------------------------------------------------------- 14 0,-2 -----------------GCUGACUCCUAGUCCAGGGCaa----------------------------------------------------------- 2 0,-2 -----------------GCUGACUCCUAGUCCAGGGCU------------------------------------------------------------ 187 0,-1 -----------------GCUGACUCCUAGUCCAGGGCUa----------------------------------------------------------- 23 0,-1 -----------------GCUGACUCCUAGUCCAGGGCUaa---------------------------------------------------------- 16 0,-1 -----------------GCUGACUCCUAGUCCAGGGCUau---------------------------------------------------------- 19 0,-1 -----------------GCUGACUCCUAGUCCAGGGCUu----------------------------------------------------------- 32 0,-1 -----------------GCUGACUCCUAGUCCAGGGCUuu---------------------------------------------------------- 24 0,-1 -----------------GCUGACUCCUAGUCCAGGGCUC----------------------------------------------------------- 135 0,0 -----------------GCUGACUCCUAGUCCAGGGCUCa---------------------------------------------------------- 75 0,0 -----------------GCUGACUCCUAGUCCAGGGCUCaa--------------------------------------------------------- 3 0,0 -----------------GCUGACUCCUAGUCCAGGGCUCau--------------------------------------------------------- 12 0,0 -----------------GCUGACUCCUAGUCCAGGGCUCc---------------------------------------------------------- 2 0,0 -----------------GCUGACUCCUAGUCCAGGGCUCu---------------------------------------------------------- 75 0,0 -----------------GCUGACUCCUAGUCCAGGGCUCuu--------------------------------------------------------- 11 0,0 -----------------GCUGACUCCUAGUCCAGGGCUCG---------------------------------------------------------- 2 0,1 >hsa-mir-34a MA:22-43;mi:64-85 Normal ggccagcugugaguguuucuuUGGCAGUGUCUUAGCUGGUUGUugugagcaauaguaaggaagCAAUCAGCAAGUAUACUGCCCUagaagugcugcacguuguggggccc ---------------------UGGCAGUGUCUUAGCUGG----------------------------------------------------------------------- 3 0,-4 ---------------------UGGCAGUGUCUUAGCUGGU---------------------------------------------------------------------- 4 0,-3 ---------------------UGGCAGUGUCUUAGCUGGUU--------------------------------------------------------------------- 11 0,-2 ---------------------UGGCAGUGUCUUAGCUGGUUaa------------------------------------------------------------------- 2 0,-2 ---------------------UGGCAGUGUCUUAGCUGGUUau------------------------------------------------------------------- 2 0,-2 ---------------------UGGCAGUGUCUUAGCUGGUUu-------------------------------------------------------------------- 2 0,-2 ---------------------UGGCAGUGUCUUAGCUGGUUuu------------------------------------------------------------------- 6 0,-2 ---------------------UGGCAGUGUCUUAGCUGGUUG-------------------------------------------------------------------- 88 0,-1 ---------------------UGGCAGUGUCUUAGCUGGUUGa------------------------------------------------------------------- 85 0,-1 ---------------------UGGCAGUGUCUUAGCUGGUUGaa------------------------------------------------------------------ 25 0,-1 ---------------------UGGCAGUGUCUUAGCUGGUUGau------------------------------------------------------------------ 2 0,-1 ---------------------UGGCAGUGUCUUAGCUGGUUGU------------------------------------------------------------------- 783 0,0 ---------------------UGGCAGUGUCUUAGCUGGUUGUa------------------------------------------------------------------ 56 0,0 ---------------------UGGCAGUGUCUUAGCUGGUUGUaa----------------------------------------------------------------- 23 0,0 ---------------------UGGCAGUGUCUUAGCUGGUUGUau----------------------------------------------------------------- 16 0,0 ---------------------UGGCAGUGUCUUAGCUGGUUGUU------------------------------------------------------------------ 588 0,1 ---------------------UGGCAGUGUCUUAGCUGGUUGUUa----------------------------------------------------------------- 25 0,1 ---------------------UGGCAGUGUCUUAGCUGGUUGUUau---------------------------------------------------------------- 2 0,1 ---------------------UGGCAGUGUCUUAGCUGGUUGUUu----------------------------------------------------------------- 108 0,1 ---------------------UGGCAGUGUCUUAGCUGGUUGUUuu---------------------------------------------------------------- 2 0,1 ---------------------UGGCAGUGUCUUAGCUGGUUGUUG----------------------------------------------------------------- 2 0,2 ---------------------UGGCAGUGUCUUAGCUGGUUGUUGU---------------------------------------------------------------- 3 0,3 ----------------------GGCAGUGUCUUAGCUGGUUGU------------------------------------------------------------------- 17 1,0 ----------------------GGCAGUGUCUUAGCUGGUUGUa------------------------------------------------------------------ 2 1,0 ----------------------GGCAGUGUCUUAGCUGGUUGUU------------------------------------------------------------------ 21 1,1 ----------------------GGCAGUGUCUUAGCUGGUUGUUu----------------------------------------------------------------- 2 1,1 ----------------------------------------------------------------AAUCAGCAAGUAUACUGCCCUu------------------------ 2 1,0 ----------------------------------------------------------------AAUCAGCAAGUAUACUGCCCUA------------------------ 2 1,1 >hsa-mir-34b mi:13-35;MA:50-71 Normal gugcucgguuugUAGGCAGUGUCAUUAGCUGAUUGuacuguggugguuaCAAUCACUAACUCCACUGCCAUcaaaacaaggcac -------------AGGCAGUGUCAUUAGCUGAUUG------------------------------------------------- 10 1,0 -------------AGGCAGUGUCAUUAGCUGAUUGU------------------------------------------------ 71 1,1 --------------------------------------------------AAUCACUAACUCCACUGCCAUC------------ 2 1,1 >hsa-mir-34c 5p:13-35;3p:46-67 Normal agucuaguuacuAGGCAGUGUAGUUAGCUGAUUGCuaauaguaccAAUCACUAACCACACGGCCAGGuaaaaagauu -----------UAGGCAGUGUAGUUAGCUGAU--------------------------------------------- 3 -1,-3 ------------AGGCAGUGUAGUUAGCUGAUU-------------------------------------------- 17 0,-2 ------------AGGCAGUGUAGUUAGCUGAUUG------------------------------------------- 15 0,-1 ------------AGGCAGUGUAGUUAGCUGAUUGa------------------------------------------ 14 0,-1 ------------AGGCAGUGUAGUUAGCUGAUUGu------------------------------------------ 11 0,-1 ------------AGGCAGUGUAGUUAGCUGAUUGC------------------------------------------ 275 0,0 ------------AGGCAGUGUAGUUAGCUGAUUGCa----------------------------------------- 2 0,0 ---------------------------------------------AAUCACUAACCACACGGCCAGu---------- 2 0,-1 ---------------------------------------------AAUCACUAACCACACGGCCAGG---------- 5 0,0 ---------------------------------------------AAUCACUAACCACACGGCCAGGa--------- 2 0,0 >hsa-mir-3545 5p:15-36;3p:54-76 Normal gcgcccgccgggucUAGUGGUCCUAAACAUUUCACAauugcgcuacagaacugUUGAACUGUUAAGAACCACUGGAcccagcgcgc ------------------------------------------------------UGAACUGUUAAGAACCACUGGu---------- 2 1,-1 >hsa-mir-3605 5p:22-44;3p:66-88 Normal acuuuauacguguaauugugaUGAGGAUGGAUAGCAAGGAAGCCgcucccaccugacccucacggCCUCCGUGUUACCUGUCCUCUAGgugggacgcucg -----------------------------------------------------------------CCUCCGUGUUACCUGUCCUCU-------------- 4 0,-2 -------------------------------------------------------------------UCCGUGUUACCUGUCCUCUAGu----------- 2 2,0 >hsa-mir-3607 5p:12-33;3p:51-70 Normal aagguugcgguGCAUGUGAUGAAGCAAAUCAGUaugaaugaauucaugauACUGUAAACGCUUUCUGAUGuacuacuca ------------------------------------------------AUACUGUAAACGCUUUCUGAUG--------- 9 -2,0 -------------------------------------------------UACUGUAAACGCUUUCUGAUG--------- 10 -1,0 --------------------------------------------------ACUGUAAACGCUUUCUGAUG--------- 24 0,0 ---------------------------------------------------CUGUAAACGCUUUCUGAUG--------- 74 1,0 ----------------------------------------------------UGUAAACGCUUUCUGAUG--------- 10 2,0 >hsa-mir-361 5p:6-27;3p:45-67 Normal ggagcUUAUCAGAAUCUCCAGGGGUACuuuauaauuucaaaaagUCCCCCAGGUGUGAUUCUGAUUUgcuuc -----UUAUCAGAAUCUCCAGGGGU----------------------------------------------- 11 0,-2 -----UUAUCAGAAUCUCCAGGGGUA---------------------------------------------- 9 0,-1 -----UUAUCAGAAUCUCCAGGGGUAa--------------------------------------------- 26 0,-1 -----UUAUCAGAAUCUCCAGGGGUAaa-------------------------------------------- 10 0,-1 -----UUAUCAGAAUCUCCAGGGGUAau-------------------------------------------- 2 0,-1 -----UUAUCAGAAUCUCCAGGGGUAu--------------------------------------------- 27 0,-1 -----UUAUCAGAAUCUCCAGGGGUAC--------------------------------------------- 157 0,0 -----UUAUCAGAAUCUCCAGGGGUACa-------------------------------------------- 37 0,0 -----UUAUCAGAAUCUCCAGGGGUACU-------------------------------------------- 12 0,1 ------UAUCAGAAUCUCCAGGGGUAC--------------------------------------------- 3 1,0 --------------------------------------------UCCCCCAGGUGUGAUUCUG--------- 3 0,-4 --------------------------------------------UCCCCCAGGUGUGAUUCUGA-------- 30 0,-3 --------------------------------------------UCCCCCAGGUGUGAUUCUGAa------- 2 0,-3 --------------------------------------------UCCCCCAGGUGUGAUUCUGAaa------ 7 0,-3 --------------------------------------------UCCCCCAGGUGUGAUUCUGAU------- 87 0,-2 --------------------------------------------UCCCCCAGGUGUGAUUCUGAUa------ 11 0,-2 --------------------------------------------UCCCCCAGGUGUGAUUCUGAUU------ 257 0,-1 --------------------------------------------UCCCCCAGGUGUGAUUCUGAUUU----- 141 0,0 --------------------------------------------UCCCCCAGGUGUGAUUCUGAUUUG---- 11 0,1 ---------------------------------------------CCCCCAGGUGUGAUUCUGAUU------ 7 1,-1 ---------------------------------------------CCCCCAGGUGUGAUUCUGAUUU----- 4 1,0 ---------------------------------------------CCCCCAGGUGUGAUUCUGAUUUG---- 21 1,1 ---------------------------------------------CCCCCAGGUGUGAUUCUGAUUUGC--- 14 1,2 ----------------------------------------------CCCCAGGUGUGAUUCUGAUU------ 3 2,-1 ----------------------------------------------CCCCAGGUGUGAUUCUGAUUUG---- 3 2,1 >hsa-mir-3611 3pM:52-72 Normal agcaggucuaauaagaauuucuuuuucuucacaauuaugaaagaaaagaaaUUGUGAAGAAAGAAAUUCUUAcuaguuuugcu ---------------------------------------------------UUGUGAAGAAAGAAAUUCU------------- 7 0,-2 ---------------------------------------------------UUGUGAAGAAAGAAAUUCUU------------ 20 0,-1 ---------------------------------------------------UUGUGAAGAAAGAAAUUCUUA----------- 5 0,0 ---------------------------------------------------UUGUGAAGAAAGAAAUUCUUAC---------- 3 0,1 >hsa-mir-3613 5p:16-37;3p:53-76 Normal ugguuggguuuggauUGUUGUACUUUUUUUUUUGUUCguugcauuuuuaggaACAAAAAAAAAAGCCCAACCCUUCacaccacuuca ---------------UGUUGUACUUUUUUUUUU------------------------------------------------------ 7 0,-4 ---------------UGUUGUACUUUUUUUUUUu----------------------------------------------------- 4 0,-4 ---------------UGUUGUACUUUUUUUUUUuu---------------------------------------------------- 4 0,-4 ---------------UGUUGUACUUUUUUUUUUGU---------------------------------------------------- 2 0,-2 ---------------UGUUGUACUUUUUUUUUUGUU--------------------------------------------------- 16 0,-1 ---------------UGUUGUACUUUUUUUUUUGUUC-------------------------------------------------- 21 0,0 ---------------UGUUGUACUUUUUUUUUUGUUCa------------------------------------------------- 5 0,0 ----------------------------------------------------ACAAAAAAAAAAGCCCAACC--------------- 2 0,-4 ----------------------------------------------------ACAAAAAAAAAAGCCCAACCCU------------- 10 0,-2 >hsa-mir-3615 3pM:51-71 Normal gacucugggacgcucagacgccgcgcggggcggggauuggucugugguccUCUCUCGGCUCCUCGCGGCUCgcggcggccgacgguu --------------------------------------------------UCUCUCGGCUCCUCGCGGCU----------------- 2 0,-1 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUuu--------------- 3 0,-1 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUCu--------------- 2 0,0 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUCG--------------- 6 0,1 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUCGu-------------- 2 0,1 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUCGC-------------- 5 0,2 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUCGCu------------- 2 0,2 >hsa-mir-362 5p:5-28;3p:42-63 Normal cuugAAUCCUUGGAACCUAGGUGUGAGUgcuauuucagugcAACACACCUAUUCAAGGAUUCAaa ----AAUCCUUGGAACCUAGGUGU----------------------------------------- 4 0,-4 ----AAUCCUUGGAACCUAGGUGUG---------------------------------------- 7 0,-3 ----AAUCCUUGGAACCUAGGUGUGA--------------------------------------- 108 0,-2 ----AAUCCUUGGAACCUAGGUGUGAa-------------------------------------- 31 0,-2 ----AAUCCUUGGAACCUAGGUGUGAaa------------------------------------- 2 0,-2 ----AAUCCUUGGAACCUAGGUGUGAG-------------------------------------- 159 0,-1 ----AAUCCUUGGAACCUAGGUGUGAGa------------------------------------- 26 0,-1 ----AAUCCUUGGAACCUAGGUGUGAGU------------------------------------- 146 0,0 -----AUCCUUGGAACCUAGGUGUGAGU------------------------------------- 2 1,0 -----------------------------------------AACACACCUAUUCAAGGAU----- 4 0,-3 -----------------------------------------AACACACCUAUUCAAGGAUU---- 22 0,-2 -----------------------------------------AACACACCUAUUCAAGGAUUC--- 9 0,-1 -----------------------------------------AACACACCUAUUCAAGGAUUCu-- 3 0,-1 -----------------------------------------AACACACCUAUUCAAGGAUUCA-- 48 0,0 -----------------------------------------AACACACCUAUUCAAGGAUUCAA- 8 0,1 ------------------------------------------ACACACCUAUUCAAGGAUUCu-- 2 1,-1 >hsa-mir-3622a 5p:14-35;3p:50-71 Normal aauagagggugcaCAGGCACGGGAGCUCAGGUGAGgcagggagcugagcUCACCUGACCUCCCAUGCCUGUgcacccucuauu -------------CAGGCACGGGAGCUCAGGUGA------------------------------------------------- 2 0,-1 >hsa-mir-363 mi:7-28;MA:50-71 Normal uguuguCGGGUGGAUCACGAUGCAAUUUugaugaguaucauaggagaaaAAUUGCACGGUAUCCAUCUGUAaacc -------------------------------------------------AAUUGCACGGUAUCCAUCU------- 2 0,-3 -------------------------------------------------AAUUGCACGGUAUCCAUCUG------ 41 0,-2 -------------------------------------------------AAUUGCACGGUAUCCAUCUGU----- 304 0,-1 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUu---- 8 0,-1 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUA---- 149 0,0 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUAg--- 2 0,0 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUAu--- 7 0,0 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUAA--- 30 0,1 --------------------------------------------------AUUGCACGGUAUCCAUCUGU----- 22 1,-1 --------------------------------------------------AUUGCACGGUAUCCAUCUGUA---- 16 1,0 --------------------------------------------------AUUGCACGGUAUCCAUCUGUAA--- 6 1,1 >hsa-mir-3647 5p:15-37;3p:62-84 Normal uugcuuucaucagcCUGAAGUGAUGAUUCACAUUCAUgucucuucucugauaaauucuugaAGAAAAUUUUUGUGUGUCUGAUCaggccucuagagggcag --------------------------------------------------------------GAAAAUUUUUGUGUGUCUGAUC----------------- 5 1,0 ---------------------------------------------------------------AAAAUUUUUGUGUGUCUGAUC----------------- 12 2,0 >hsa-mir-365-1 3pM:56-77 Normal accgcagggaaaaugagggacuuuugggggcagauguguuuccauuccacuaucaUAAUGCCCCUAAAAAUCCUUAUugcucuugca ---------------AGGGACUUUUGGGGGCAGAUGUG------------------------------------------------- 7 -------------------------------------------------------UAAUGCCCCUAAAAAUCCU------------- 7 0,-3 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUU------------ 65 0,-2 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUu----------- 8 0,-2 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUuu---------- 7 0,-2 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUA----------- 72 0,-1 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAa---------- 14 0,-1 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAc---------- 5 0,-1 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAU---------- 283 0,0 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAUa--------- 6 0,0 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAUU--------- 16 0,1 --------------------------------------------------------AAUGCCCCUAAAAAUCCUUA----------- 3 1,-1 --------------------------------------------------------AAUGCCCCUAAAAAUCCUUAU---------- 10 1,0 >hsa-mir-365-2 mi:29-50;MA:68-89 Normal agaguguucaaggacagcaagaaaaaugAGGGACUUUCAGGGGCAGCUGUguuuucugacucagucaUAAUGCCCCUAAAAAUCCUUAUuguucuugcagugugcaucggg ---------------------------GAGGGACUUUCAGGGGCAGCUGU------------------------------------------------------------- 2 -1,0 ----------------------------AGGGACUUUCAGGGGCAGCUGUG------------------------------------------------------------ 2 0,1 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCU------------------------- 7 0,-3 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUU------------------------ 65 0,-2 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUu----------------------- 8 0,-2 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUuu---------------------- 7 0,-2 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUA----------------------- 72 0,-1 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAa---------------------- 14 0,-1 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAc---------------------- 5 0,-1 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAU---------------------- 283 0,0 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAUa--------------------- 6 0,0 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAUU--------------------- 16 0,1 --------------------------------------------------------------------AAUGCCCCUAAAAAUCCUUA----------------------- 3 1,-1 --------------------------------------------------------------------AAUGCCCCUAAAAAUCCUUAU---------------------- 10 1,0 >hsa-mir-3653 3pM:75-92 Normal ucccuggggaccccuggcagccccuccugaugauucuucuuccugagcacgcucaugaugagcaaacugagccuCUAAGAAGUUGACUGAAGgggcugcuuccccaagga ------------------------------------------------------------------------CUCUAAGAAGUUGACUGAAG------------------ 112 -2,0 -------------------------------------------------------------------------UCUAAGAAGUUGACUGAAG------------------ 15 -1,0 --------------------------------------------------------------------------CUAAGAAGUUGACUGAAG------------------ 52 0,0 >hsa-mir-3656 3pM:49-65 Normal cuuucggccagcgggacggcauccgaggugggcuaggcucgggcccguGGCGGGUGCGGGGGUGGgagg ------------------------------------------------GGCGGGUGCGGGGGUGGG--- 113 0,1 ------------------------------------------------GGCGGGUGCGGGGGUGGGc-- 52 0,1 >hsa-mir-3664 5p:21-42;3p:59-80 Normal cuguaaacuugaagguagggAACUCUGUCUUCACUCAUGAGUaccuuccaacacgagcUCUCAGGAGUAAAGACAGAGUUcccuaccuucaauguggau ---------------------------------------------------------CUCUCAGGAGUAAAGACAGAGU-------------------- 2 -1,-1 >hsa-mir-3676 3pM:60-79 Normal uugguuaaagcgccugucuaguaaacaggagauccuggguucgaaucccagcggugccuCCGUGUUUCCCCCACGCUUUugccaa --------------------GUAAACAGGAGAUCCUGGGU--------------------------------------------- 30 ---------------------UAAACAGGAGAUCCUGGGU--------------------------------------------- 4 ---------------------UAAACAGGAGAUCCUGGGUUC------------------------------------------- 2 ---------------------UAAACAGGAGAUCCUGGGUUCG------------------------------------------ 24 ---------------------UAAACAGGAGAUCCUGGGUUCGu----------------------------------------- 2 ---------------------UAAACAGGAGAUCCUGGGUUCGA----------------------------------------- 15 ----------------------AAACAGGAGAUCCUGGGUUCG------------------------------------------ 29 ----------------------AAACAGGAGAUCCUGGGUUCGA----------------------------------------- 13 -----------------------AACAGGAGAUCCUGGGUUCG------------------------------------------ 6 -----------------------AACAGGAGAUCCUGGGUUCGA----------------------------------------- 2 -----------------------------------------------------------CCGUGUUUCCCCCACGCUUU------ 4 0,0 >hsa-mir-369 5p:9-30;3p:44-64 Normal uugaagggAGAUCGACCGUGUUAUAUUCGCuuuauugacuucgAAUAAUACAUGGUUGAUCUUUucucag --------AGAUCGACCGUGUUAUAUUCG----------------------------------------- 31 0,-1 --------AGAUCGACCGUGUUAUAUUCGC---------------------------------------- 2 0,0 ------------------------------------------GAAUAAUACAUGGUUGAUCUUU------ 4 -1,0 -------------------------------------------AAUAAUACAUGGUUGAUCUU------- 15 0,-1 -------------------------------------------AAUAAUACAUGGUUGAUCUUU------ 208 0,0 -------------------------------------------AAUAAUACAUGGUUGAUCUUUa----- 2 0,0 -------------------------------------------AAUAAUACAUGGUUGAUCUUUU----- 7 0,1 >hsa-mir-370 3pM:48-69 Normal agacagagaagccaggucacgucucugcaguuacacagcucacgaguGCCUGCUGGGGUGGAACCUGGUcugucu ----------------------------------------------UGCCUGCUGGGGUGGAACCUGGU------ 2 -1,0 -----------------------------------------------GCCUGCUGGGGUGGAACCU--------- 2 0,-3 -----------------------------------------------GCCUGCUGGGGUGGAACCUG-------- 3 0,-2 -----------------------------------------------GCCUGCUGGGGUGGAACCUGa------- 7 0,-2 -----------------------------------------------GCCUGCUGGGGUGGAACCUGu------- 3 0,-2 -----------------------------------------------GCCUGCUGGGGUGGAACCUGG------- 47 0,-1 -----------------------------------------------GCCUGCUGGGGUGGAACCUGGa------ 15 0,-1 -----------------------------------------------GCCUGCUGGGGUGGAACCUGGaa----- 2 0,-1 -----------------------------------------------GCCUGCUGGGGUGGAACCUGGU------ 301 0,0 -----------------------------------------------GCCUGCUGGGGUGGAACCUGGUa----- 33 0,0 -----------------------------------------------GCCUGCUGGGGUGGAACCUGGUaa---- 9 0,0 -----------------------------------------------GCCUGCUGGGGUGGAACCUGGUau---- 4 0,0 -----------------------------------------------GCCUGCUGGGGUGGAACCUGGUu----- 34 0,0 -----------------------------------------------GCCUGCUGGGGUGGAACCUGGUuu---- 3 0,0 ------------------------------------------------CCUGCUGGGGUGGAACCUGGU------ 2 1,0 >hsa-mir-374a MA:12-33;mi:42-63 Normal uacaucggccaUUAUAAUACAACCUGAUAAGUGuuauagcaCUUAUCAGAUUGUAUUGUAAUUgucugugua -----------UUAUAAUACAACCUGAUAAG----------------------------------------- 21 0,-2 -----------UUAUAAUACAACCUGAUAAGa---------------------------------------- 2 0,-2 -----------UUAUAAUACAACCUGAUAAGU---------------------------------------- 191 0,-1 -----------UUAUAAUACAACCUGAUAAGUa--------------------------------------- 5 0,-1 -----------UUAUAAUACAACCUGAUAAGUaa-------------------------------------- 2 0,-1 -----------UUAUAAUACAACCUGAUAAGUG--------------------------------------- 200 0,0 -----------UUAUAAUACAACCUGAUAAGUGa-------------------------------------- 38 0,0 -----------UUAUAAUACAACCUGAUAAGUGU-------------------------------------- 9 0,1 ------------UAUAAUACAACCUGAUAAGU---------------------------------------- 3 1,-1 ------------UAUAAUACAACCUGAUAAGUG--------------------------------------- 3 1,0 -------------AUAAUACAACCUGAUAAGU---------------------------------------- 2 2,-1 ----------------------------------------ACUUAUCAGAUUGUAUUGU------------- 2 -1,-4 -----------------------------------------CUUAUCAGAUUGUAUUGUAA----------- 7 0,-2 -----------------------------------------CUUAUCAGAUUGUAUUGUAAU---------- 17 0,-1 -----------------------------------------CUUAUCAGAUUGUAUUGUAAUU--------- 47 0,0 -----------------------------------------CUUAUCAGAUUGUAUUGUAAUUa-------- 2 0,0 ------------------------------------------UUAUCAGAUUGUAUUGUAAUU--------- 2 1,0 >hsa-mir-374b MA:11-32;mi:41-62 Normal acucggauggAUAUAAUACAACCUGCUAAGUGuccuagcaCUUAGCAGGUUGUAUUAUCAUUguccgugucu ----------AUAUAAUACAACCUGCUAA------------------------------------------- 2 0,-3 ----------AUAUAAUACAACCUGCUAAG------------------------------------------ 23 0,-2 ----------AUAUAAUACAACCUGCUAAGU----------------------------------------- 247 0,-1 ----------AUAUAAUACAACCUGCUAAGUG---------------------------------------- 187 0,0 ----------AUAUAAUACAACCUGCUAAGUGa--------------------------------------- 61 0,0 ----------AUAUAAUACAACCUGCUAAGUGU--------------------------------------- 58 0,1 -----------UAUAAUACAACCUGCUAAGUGU--------------------------------------- 2 1,1 >hsa-mir-375 3pM:40-61 Normal ccccgcgacgagccccucgcacaaaccggaccugagcguUUUGUUCGUUCGGCUCGCGUGAggc --------------------------------------UUUUGUUCGUUCGGCUCGCGUGA--- 7 -1,0 ---------------------------------------UUUGUUCGUUCGGCUCGC------- 2 0,-4 ---------------------------------------UUUGUUCGUUCGGCUCGCG------ 3 0,-3 ---------------------------------------UUUGUUCGUUCGGCUCGCGU----- 15 0,-2 ---------------------------------------UUUGUUCGUUCGGCUCGCGUu---- 2 0,-2 ---------------------------------------UUUGUUCGUUCGGCUCGCGUG---- 24 0,-1 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGu--- 28 0,-1 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGA--- 525 0,0 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGAa-- 37 0,0 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGAaa- 2 0,0 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGAu-- 9 0,0 ----------------------------------------UUGUUCGUUCGGCUCGCGUGA--- 14 1,0 ----------------------------------------UUGUUCGUUCGGCUCGCGUGAa-- 2 1,0 >hsa-mir-376a-1 mi:7-28;MA:44-64 Normal uaaaagGUAGAUUCUCCUUCUAUGAGUAcauuauuuaugauuaAUCAUAGAGGAAAAUCCACGUuuuc -----GGUAGAUUCUCCUUCUAUGAGUu---------------------------------------- 2 -1,-1 ------GUAGAUUCUCCUUCUAUGAG------------------------------------------ 2 0,-2 ------GUAGAUUCUCCUUCUAUGAGU----------------------------------------- 87 0,-1 ------GUAGAUUCUCCUUCUAUGAGUA---------------------------------------- 6 0,0 ------GUAGAUUCUCCUUCUAUGAGUAC--------------------------------------- 18 0,1 ------------------------------------------AAUCAUAGAGGAAAAUCCACGU---- 14 -1,0 -------------------------------------------AUCAUAGAGGAAAAUCCACGU---- 48 0,0 -------------------------------------------AUCAUAGAGGAAAAUCCACGUU--- 6 0,1 >hsa-mir-376a-2 3pM:50-70 Normal gguauuuaaaagguagauuuuccuucuaugguuacguguuugaugguuaAUCAUAGAGGAAAAUCCACGUuuucaguauc ------------GUAGAUUUUCCUUCUAUGGUU----------------------------------------------- 11 ------------GUAGAUUUUCCUUCUAUGGUUA---------------------------------------------- 13 ------------------------------------------------AAUCAUAGAGGAAAAUCCACGU---------- 14 -1,0 -------------------------------------------------AUCAUAGAGGAAAAUCCACGU---------- 48 0,0 -------------------------------------------------AUCAUAGAGGAAAAUCCACGUU--------- 6 0,1 >hsa-mir-376b 3pM:62-83 Normal caguccuucuuugguauuuaaaacguggauauuccuucuauguuuacgugauuccugguuaAUCAUAGAGGAAAAUCCAUGUUuucaguaucaaaugcug ------------------------GUGGAUAUUCCUUCUAUGUUU------------------------------------------------------- 8 ------------------------GUGGAUAUUCCUUCUAUGUUUA------------------------------------------------------ 2 -------------------------UGGAUAUUCCUUCUAUGUUU------------------------------------------------------- 5 -------------------------------------------------------------AUCAUAGAGGAAAAUCCAUGU------------------ 262 0,-1 -------------------------------------------------------------AUCAUAGAGGAAAAUCCAUGUaa---------------- 2 0,-1 -------------------------------------------------------------AUCAUAGAGGAAAAUCCAUGUU----------------- 76 0,0 -------------------------------------------------------------AUCAUAGAGGAAAAUCCAUGUUa---------------- 5 0,0 -------------------------------------------------------------AUCAUAGAGGAAAAUCCAUGUUU---------------- 15 0,1 --------------------------------------------------------------UCAUAGAGGAAAAUCCAUGUUU---------------- 2 1,1 ---------------------------------------------------------------CAUAGAGGAAAAUCCAUGU------------------ 2 2,-1 >hsa-mir-376c 3pM:43-63 Normal aaaagguggauauuccuucuauguuuauguuauuuaugguuaAACAUAGAGGAAAUUCCACGUuuu -----GUGGAUAUUCCUUCUAUGUUU---------------------------------------- 8 -----GUGGAUAUUCCUUCUAUGUUUA--------------------------------------- 2 ------UGGAUAUUCCUUCUAUGUUU---------------------------------------- 5 -----------------------------------------AAACAUAGAGGAAAUUCCACG---- 2 -1,-1 ------------------------------------------AACAUAGAGGAAAUUCCA------ 10 0,-3 ------------------------------------------AACAUAGAGGAAAUUCCACG---- 33 0,-1 ------------------------------------------AACAUAGAGGAAAUUCCACGa--- 4 0,-1 ------------------------------------------AACAUAGAGGAAAUUCCACGc--- 7 0,-1 ------------------------------------------AACAUAGAGGAAAUUCCACGg--- 7 0,-1 ------------------------------------------AACAUAGAGGAAAUUCCACGU--- 1290 0,0 ------------------------------------------AACAUAGAGGAAAUUCCACGUa-- 11 0,0 ------------------------------------------AACAUAGAGGAAAUUCCACGUaa- 5 0,0 ------------------------------------------AACAUAGAGGAAAUUCCACGUU-- 72 0,1 ------------------------------------------AACAUAGAGGAAAUUCCACGUUa- 4 0,1 ------------------------------------------AACAUAGAGGAAAUUCCACGUUU- 9 0,2 -------------------------------------------ACAUAGAGGAAAUUCCACGU--- 26 1,0 -------------------------------------------ACAUAGAGGAAAUUCCACGUUU- 6 1,2 --------------------------------------------CAUAGAGGAAAUUCCACGUUU- 4 2,2 >hsa-mir-377 mi:7-28;MA:45-66 Normal uugagcAGAGGUUGCCCUUGGUGAAUUCgcuuuauuuauguugaAUCACACAAAGGCAACUUUUGUuug ------AGAGGUUGCCCUUGGUGAAU------------------------------------------- 37 0,-2 ------AGAGGUUGCCCUUGGUGAAUU------------------------------------------ 13 0,-1 ------AGAGGUUGCCCUUGGUGAAUUC----------------------------------------- 81 0,0 ------AGAGGUUGCCCUUGGUGAAUUCu---------------------------------------- 2 0,0 ------AGAGGUUGCCCUUGGUGAAUUCG---------------------------------------- 4 0,1 -------------------------------------------AAUCACACAAAGGCAACUUUUG---- 14 -1,-1 -------------------------------------------AAUCACACAAAGGCAACUUUUGU--- 30 -1,0 --------------------------------------------AUCACACAAAGGCAACUUUU----- 2 0,-2 --------------------------------------------AUCACACAAAGGCAACUUUUuu--- 6 0,-2 --------------------------------------------AUCACACAAAGGCAACUUUUG---- 42 0,-1 --------------------------------------------AUCACACAAAGGCAACUUUUGa--- 17 0,-1 --------------------------------------------AUCACACAAAGGCAACUUUUGc--- 3 0,-1 --------------------------------------------AUCACACAAAGGCAACUUUUGU--- 899 0,0 --------------------------------------------AUCACACAAAGGCAACUUUUGUU-- 8 0,1 --------------------------------------------AUCACACAAAGGCAACUUUUGUUU- 2 0,2 >hsa-mir-378 mi:5-26;MA:43-63 Normal agggCUCCUGACUCCAGGUCCUGUGUguuaccuagaaauagcACUGGACUUGGAGUCAGAAGGccu ----CUCCUGACUCCAGGUCCUGU------------------------------------------ 6 0,-2 ----CUCCUGACUCCAGGUCCUGUuu---------------------------------------- 2 0,-2 ----CUCCUGACUCCAGGUCCUGUG----------------------------------------- 15 0,-1 ----CUCCUGACUCCAGGUCCUGUGa---------------------------------------- 25 0,-1 ----CUCCUGACUCCAGGUCCUGUGU---------------------------------------- 255 0,0 ----CUCCUGACUCCAGGUCCUGUGUu--------------------------------------- 3 0,0 -----UCCUGACUCCAGGUCCUGUGU---------------------------------------- 27 1,0 -----UCCUGACUCCAGGUCCUGUGUu--------------------------------------- 2 1,0 -----UCCUGACUCCAGGUCCUGUGUGU-------------------------------------- 3 1,2 -----------------------------------------CACUGGACUUGGAGUCAGA------ 2 -1,-3 -----------------------------------------CACUGGACUUGGAGUCAGAAG---- 2 -1,-1 -----------------------------------------CACUGGACUUGGAGUCAGAAGG--- 4 -1,0 -----------------------------------------CACUGGACUUGGAGUCAGAAGGa-- 2 -1,0 -----------------------------------------CACUGGACUUGGAGUCAGAAGGC-- 11 -1,1 -----------------------------------------CACUGGACUUGGAGUCAGAAGGCa- 2 -1,1 ------------------------------------------ACUGGACUUGGAGUCAGA------ 645 0,-3 ------------------------------------------ACUGGACUUGGAGUCAGAg----- 2 0,-3 ------------------------------------------ACUGGACUUGGAGUCAGAu----- 3 0,-3 ------------------------------------------ACUGGACUUGGAGUCAGAA----- 251 0,-2 ------------------------------------------ACUGGACUUGGAGUCAGAAc---- 4 0,-2 ------------------------------------------ACUGGACUUGGAGUCAGAAu---- 41 0,-2 ------------------------------------------ACUGGACUUGGAGUCAGAAG---- 3106 0,-1 ------------------------------------------ACUGGACUUGGAGUCAGAAGc--- 3 0,-1 ------------------------------------------ACUGGACUUGGAGUCAGAAGu--- 170 0,-1 ------------------------------------------ACUGGACUUGGAGUCAGAAGuu-- 2 0,-1 ------------------------------------------ACUGGACUUGGAGUCAGAAGG--- 5824 0,0 ------------------------------------------ACUGGACUUGGAGUCAGAAGGa-- 4368 0,0 ------------------------------------------ACUGGACUUGGAGUCAGAAGGaa- 907 0,0 ------------------------------------------ACUGGACUUGGAGUCAGAAGGau- 50 0,0 ------------------------------------------ACUGGACUUGGAGUCAGAAGGg-- 22 0,0 ------------------------------------------ACUGGACUUGGAGUCAGAAGGu-- 774 0,0 ------------------------------------------ACUGGACUUGGAGUCAGAAGGuu- 31 0,0 ------------------------------------------ACUGGACUUGGAGUCAGAAGGC-- 12677 0,1 ------------------------------------------ACUGGACUUGGAGUCAGAAGGCa- 2503 0,1 ------------------------------------------ACUGGACUUGGAGUCAGAAGGCaa 398 0,1 ------------------------------------------ACUGGACUUGGAGUCAGAAGGCau 482 0,1 ------------------------------------------ACUGGACUUGGAGUCAGAAGGCg- 65 0,1 ------------------------------------------ACUGGACUUGGAGUCAGAAGGCu- 451 0,1 ------------------------------------------ACUGGACUUGGAGUCAGAAGGCuu 14 0,1 ------------------------------------------ACUGGACUUGGAGUCAGAAGGCC- 5 0,2 -------------------------------------------CUGGACUUGGAGUCAGAA----- 6 1,-2 -------------------------------------------CUGGACUUGGAGUCAGAAG---- 100 1,-1 -------------------------------------------CUGGACUUGGAGUCAGAAGu--- 4 1,-1 -------------------------------------------CUGGACUUGGAGUCAGAAGG--- 268 1,0 -------------------------------------------CUGGACUUGGAGUCAGAAGGa-- 181 1,0 -------------------------------------------CUGGACUUGGAGUCAGAAGGaa- 59 1,0 -------------------------------------------CUGGACUUGGAGUCAGAAGGau- 2 1,0 -------------------------------------------CUGGACUUGGAGUCAGAAGGu-- 54 1,0 -------------------------------------------CUGGACUUGGAGUCAGAAGGC-- 1051 1,1 -------------------------------------------CUGGACUUGGAGUCAGAAGGCa- 215 1,1 -------------------------------------------CUGGACUUGGAGUCAGAAGGCaa 80 1,1 -------------------------------------------CUGGACUUGGAGUCAGAAGGCau 64 1,1 -------------------------------------------CUGGACUUGGAGUCAGAAGGCg- 3 1,1 -------------------------------------------CUGGACUUGGAGUCAGAAGGCu- 149 1,1 -------------------------------------------CUGGACUUGGAGUCAGAAGGCuu 13 1,1 -------------------------------------------CUGGACUUGGAGUCAGAAGGCC- 2 1,2 -------------------------------------------CUGGACUUGGAGUCAGAAGGCCa 3 1,2 --------------------------------------------UGGACUUGGAGUCAGAAGG--- 8 2,0 --------------------------------------------UGGACUUGGAGUCAGAAGGa-- 4 2,0 --------------------------------------------UGGACUUGGAGUCAGAAGGaa- 2 2,0 --------------------------------------------UGGACUUGGAGUCAGAAGGC-- 39 2,1 --------------------------------------------UGGACUUGGAGUCAGAAGGCa- 2 2,1 --------------------------------------------UGGACUUGGAGUCAGAAGGCu- 2 2,1 >hsa-mir-378b 3pM:34-52 Normal ggucauugagucuucaaggcuaguggaaagagcACUGGACUUGGAGGCAGAAagacc ---------------------------------ACUGGACUUGGAGGCAGAA----- 49 0,0 ---------------------------------ACUGGACUUGGAGGCAGAAg---- 5 0,0 >hsa-mir-378c 5pM:11-35 Normal ggaggccaucACUGGACUUGGAGUCAGAAGAGUGGagucgggucagacuucaacucugacuuugaagguggugagugccuc --------UCACUGGACUUGGAGUCAGAAG--------------------------------------------------- 2 -2,-5 --------UCACUGGACUUGGAGUCAGAAGg-------------------------------------------------- 2 -2,-5 ---------CACUGGACUUGGAGUCAGAAG--------------------------------------------------- 2 -1,-5 ----------ACUGGACUUGGAGUCAGAAG--------------------------------------------------- 3106 0,-5 ----------ACUGGACUUGGAGUCAGAAGc-------------------------------------------------- 3 0,-5 ----------ACUGGACUUGGAGUCAGAAGu-------------------------------------------------- 170 0,-5 ----------ACUGGACUUGGAGUCAGAAGuu------------------------------------------------- 2 0,-5 ----------ACUGGACUUGGAGUCAGAAGA-------------------------------------------------- 476 0,-4 ----------ACUGGACUUGGAGUCAGAAGAa------------------------------------------------- 131 0,-4 ----------ACUGGACUUGGAGUCAGAAGAaa------------------------------------------------ 80 0,-4 ----------ACUGGACUUGGAGUCAGAAGAau------------------------------------------------ 2 0,-4 ----------ACUGGACUUGGAGUCAGAAGAc------------------------------------------------- 31 0,-4 ----------ACUGGACUUGGAGUCAGAAGAu------------------------------------------------- 5 0,-4 -----------CUGGACUUGGAGUCAGAAG--------------------------------------------------- 100 1,-5 -----------CUGGACUUGGAGUCAGAAGu-------------------------------------------------- 4 1,-5 -----------CUGGACUUGGAGUCAGAAGA-------------------------------------------------- 17 1,-4 -----------CUGGACUUGGAGUCAGAAGAa------------------------------------------------- 4 1,-4 -----------CUGGACUUGGAGUCAGAAGAaa------------------------------------------------ 5 1,-4 -----------CUGGACUUGGAGUCAGAAGAc------------------------------------------------- 2 1,-4 >hsa-mir-378d-1 3pM:31-50 Normal acuguuucuguccuuguucuuguuguuauuACUGGACUUGGAGUCAGAAAcagg ------------------------------ACUGGACUUGGAGUCAGA------ 645 0,-2 ------------------------------ACUGGACUUGGAGUCAGAg----- 2 0,-2 ------------------------------ACUGGACUUGGAGUCAGAu----- 3 0,-2 ------------------------------ACUGGACUUGGAGUCAGAA----- 251 0,-1 ------------------------------ACUGGACUUGGAGUCAGAAc---- 4 0,-1 ------------------------------ACUGGACUUGGAGUCAGAAu---- 41 0,-1 ------------------------------ACUGGACUUGGAGUCAGAAA---- 544 0,0 ------------------------------ACUGGACUUGGAGUCAGAAAg--- 12 0,0 ------------------------------ACUGGACUUGGAGUCAGAAAu--- 6 0,0 -------------------------------CUGGACUUGGAGUCAGAA----- 6 1,-1 -------------------------------CUGGACUUGGAGUCAGAAA---- 26 1,0 >hsa-mir-378d-2 5pM:22-41 Normal gaaugguuacaaggagagaacACUGGACUUGGAGUCAGAAAacuuucauccaagucauucccugcucuaagucccauuucuguuccaugagauuguuu --------------------CACUGGACUUGGAGUCAGA----------------------------------------------------------- 2 -1,-2 ---------------------ACUGGACUUGGAGUCAGA----------------------------------------------------------- 645 0,-2 ---------------------ACUGGACUUGGAGUCAGAg---------------------------------------------------------- 2 0,-2 ---------------------ACUGGACUUGGAGUCAGAu---------------------------------------------------------- 3 0,-2 ---------------------ACUGGACUUGGAGUCAGAA---------------------------------------------------------- 251 0,-1 ---------------------ACUGGACUUGGAGUCAGAAc--------------------------------------------------------- 4 0,-1 ---------------------ACUGGACUUGGAGUCAGAAu--------------------------------------------------------- 41 0,-1 ---------------------ACUGGACUUGGAGUCAGAAA--------------------------------------------------------- 544 0,0 ---------------------ACUGGACUUGGAGUCAGAAAg-------------------------------------------------------- 12 0,0 ---------------------ACUGGACUUGGAGUCAGAAAu-------------------------------------------------------- 6 0,0 ---------------------ACUGGACUUGGAGUCAGAAAA-------------------------------------------------------- 140 0,1 ---------------------ACUGGACUUGGAGUCAGAAAAa------------------------------------------------------- 42 0,1 ---------------------ACUGGACUUGGAGUCAGAAAAaa------------------------------------------------------ 15 0,1 ----------------------CUGGACUUGGAGUCAGAA---------------------------------------------------------- 6 1,-1 ----------------------CUGGACUUGGAGUCAGAAA--------------------------------------------------------- 26 1,0 >hsa-mir-378e 3pM:58-76 Normal cugacuccaguguccaggccaggggcagacaguggacagagaacagugcccaagaccACUGGACUUGGAGUCAGGAcau ---------------------------------------------------------ACUGGACUUGGAGUCAGGA--- 24 0,0 ---------------------------------------------------------ACUGGACUUGGAGUCAGGAg-- 7 0,0 >hsa-mir-378f 3pM:52-71 Normal gucagguccuggacucccauaguuuucaggcugcuaaacaacagaacgagcACUGGACUUGGAGCCAGAAGucuuggg ---------------------------------------------------ACUGGACUUGGAGCCAGAAG------- 76 0,0 ---------------------------------------------------ACUGGACUUGGAGCCAGAAGg------ 9 0,0 ----------------------------------------------------CUGGACUUGGAGCCAGAAG------- 2 1,0 >hsa-mir-378g 5pM:2-21 Normal cACUGGGCUUGGAGUCAGAAGaccuggcuccagcccagcuc -ACUGGGCUUGGAGUCAGAAG-------------------- 37 0,0 -ACUGGGCUUGGAGUCAGAAGg------------------- 8 0,0 --CUGGGCUUGGAGUCAGAAG-------------------- 4 1,0 >hsa-mir-378h 5pM:9-29 Normal acaggaacACUGGACUUGGUGUCAGAUGGgaugagcccuggcucuguuuccuagcagcaaucugaucuugagcuagucacugg --------ACUGGACUUGGUGUCAGA--------------------------------------------------------- 2 0,-3 >hsa-mir-379 MA:6-26;mi:44-65 Normal agagaUGGUAGACUAUGGAACGUAGGcguuaugauuucugaccUAUGUAACAUGGUCCACUAACUcu -----UGGUAGACUAUGGAACGUAG------------------------------------------ 116 0,-1 -----UGGUAGACUAUGGAACGUAGa----------------------------------------- 4 0,-1 -----UGGUAGACUAUGGAACGUAGG----------------------------------------- 214 0,0 -----UGGUAGACUAUGGAACGUAGGa---------------------------------------- 85 0,0 -----UGGUAGACUAUGGAACGUAGGaa--------------------------------------- 17 0,0 -----UGGUAGACUAUGGAACGUAGGu---------------------------------------- 27 0,0 -----UGGUAGACUAUGGAACGUAGGC---------------------------------------- 2 0,1 ------GGUAGACUAUGGAACGUAGG----------------------------------------- 4 1,0 ------GGUAGACUAUGGAACGUAGGa---------------------------------------- 2 1,0 >hsa-mir-380 mi:5-26;MA:40-61 Normal aagaUGGUUGACCAUAGAACAUGCGCuaucucugugucgUAUGUAAUAUGGUCCACAUCUU ---AUGGUUGACCAUAGAACAUGCG------------------------------------ 2 -1,-1 >hsa-mir-381 3pM:49-70 Normal uacuuaaagcgagguugcccuuuguauauucgguuuauugacauggaaUAUACAAGGGCAAGCUCUCUGUgagua -------AGCGAGGUUGCCCUUUGUAU------------------------------------------------ 2 -------AGCGAGGUUGCCCUUUGUAUAUU--------------------------------------------- 2 -----------------------------------------------AUAUACAAGGGCAAGCUCUCa------- 2 -1,-3 -----------------------------------------------AUAUACAAGGGCAAGCUCUCUGU----- 2 -1,0 ------------------------------------------------UAUACAAGGGCAAGCUCUCUG------ 7 0,-1 ------------------------------------------------UAUACAAGGGCAAGCUCUCUGU----- 145 0,0 ------------------------------------------------UAUACAAGGGCAAGCUCUCUGUa---- 10 0,0 -------------------------------------------------AUACAAGGGCAAGCUCUCUGU----- 9 1,0 >hsa-mir-382 5pM:11-32 Normal uacuugaagaGAAGUUGUUCGUGGUGGAUUCGcuuuacuuaugacgaaucauucacggacaacacuuuuuucagua ----------GAAGUUGUUCGUGGUGGAUU---------------------------------------------- 12 0,-2 ----------GAAGUUGUUCGUGGUGGAUUC--------------------------------------------- 40 0,-1 ----------GAAGUUGUUCGUGGUGGAUUCa-------------------------------------------- 8 0,-1 ----------GAAGUUGUUCGUGGUGGAUUCu-------------------------------------------- 5 0,-1 ----------GAAGUUGUUCGUGGUGGAUUCG-------------------------------------------- 328 0,0 ----------GAAGUUGUUCGUGGUGGAUUCGa------------------------------------------- 40 0,0 ----------GAAGUUGUUCGUGGUGGAUUCGu------------------------------------------- 28 0,0 -----------AAGUUGUUCGUGGUGGAUUC--------------------------------------------- 6 1,-1 -----------AAGUUGUUCGUGGUGGAUUCG-------------------------------------------- 53 1,0 -----------AAGUUGUUCGUGGUGGAUUCGa------------------------------------------- 11 1,0 -----------AAGUUGUUCGUGGUGGAUUCGu------------------------------------------- 3 1,0 ------------AGUUGUUCGUGGUGGAUUCG-------------------------------------------- 12 2,0 ------------AGUUGUUCGUGGUGGAUUCGa------------------------------------------- 2 2,0 ------------AGUUGUUCGUGGUGGAUUCGC------------------------------------------- 2 2,1 ------------AGUUGUUCGUGGUGGAUUCGCU------------------------------------------ 56 2,2 ----------------------------------------------AAUCAUUCACGGACAACACUU--------- 33 ----------------------------------------------AAUCAUUCACGGACAACACUUU-------- 33 >hsa-mir-383 5pM:7-28 Normal cuccucAGAUCAGAAGGUGAUUGUGGCUuuggguggauauuaaucagccacagcacugccuggucagaaagag -----CAGAUCAGAAGGUGAUUGUGGaa--------------------------------------------- 2 -1,-2 ------AGAUCAGAAGGUGAUUGUG------------------------------------------------ 3 0,-3 ------AGAUCAGAAGGUGAUUGUGG----------------------------------------------- 2 0,-2 ------AGAUCAGAAGGUGAUUGUGGa---------------------------------------------- 4 0,-2 ------AGAUCAGAAGGUGAUUGUGGaa--------------------------------------------- 3 0,-2 ------AGAUCAGAAGGUGAUUGUGGCaa-------------------------------------------- 3 0,-1 ------AGAUCAGAAGGUGAUUGUGGCU--------------------------------------------- 10 0,0 ------AGAUCAGAAGGUGAUUGUGGCUU-------------------------------------------- 4 0,1 >hsa-mir-3913-1 5p:23-44;3p:59-80 Normal uuguuuauaauaaacugaaauaUUUGGGACUGAUCUUGAUGUCUgccaaaaccuuggcAGACAUCAAGAUCAGUCCCAAAuauuucaguuuauuauagacag ----------------------UUUGGGACUGAUCUUGAUGUCU---------------------------------------------------------- 3 0,0 -----------------------UUGGGACUGAUCUUGAUGUCU---------------------------------------------------------- 2 1,0 >hsa-mir-3913-2 5pM:22-43 Normal ugucuauaauaaacugaaauaUUUGGGACUGAUCUUGAUGUCUgccaagguuuuggcagacaucaagaucagucccaaauauuucaguuuauuauaaaca ---------------------UUUGGGACUGAUCUUGAUGUCU--------------------------------------------------------- 3 0,0 ----------------------UUGGGACUGAUCUUGAUGUCU--------------------------------------------------------- 2 1,0 >hsa-mir-3926-1 5pM:11-31 Normal aaaauggagcUGGCCAAAAAGCAGGCAGAGAcuuuaaaagcgucucugccugcuuuuuggccagcuccguuuu --------GCUGGCCAAAAAGCAGGCAGA-------------------------------------------- 2 -2,-2 >hsa-mir-3926-2 5pM:6-26 Normal ggagcUGGCCAAAAAGCAGGCAGAGAcgcuuuuaaagucucugccugcuuuuuggccagcucc ---GCUGGCCAAAAAGCAGGCAGA--------------------------------------- 2 -2,-2 >hsa-mir-3928 3pM:37-58 Normal gcugaagcucuaagguuccgccugcgggcaggaagcGGAGGAACCUUGGAGCUUCGGC ------------------------------------GGAGGAACCUUGGAGCUUCGGu 2 0,-1 ------------------------------------GGAGGAACCUUGGAGCUUCGGuu 3 0,-1 ------------------------------------GGAGGAACCUUGGAGCUUCGGC 2 0,0 -------------------------------------GAGGAACCUUGGAGCUUCGGCa 2 1,0 >hsa-mir-3940 5p:23-42;3p:57-78 Normal gcuuaucgaggaaaagaucgagGUGGGUUGGGGCGGGCUCUGgggauuuggucucaCAGCCCGGAUCCCAGCCCACUUaccuugguuacucuccuuccuucu --------------------------------------------------------CAGCCCGGAUCCCAGCCCACU------------------------- 3 0,-1 >hsa-mir-409 5p:15-37;3p:47-68 Normal ugguacucggggagAGGUUACCCGAGCAACUUUGCAUcuggacgacGAAUGUUGCUCGGUGAACCCCUuuucgguauca --------------AGGUUACCCGAGCAACUUUG--------------------------------------------- 2 0,-3 --------------AGGUUACCCGAGCAACUUUGC-------------------------------------------- 11 0,-2 --------------AGGUUACCCGAGCAACUUUGCA------------------------------------------- 41 0,-1 --------------AGGUUACCCGAGCAACUUUGCAU------------------------------------------ 76 0,0 --------------AGGUUACCCGAGCAACUUUGCAUC----------------------------------------- 23 0,1 --------------AGGUUACCCGAGCAACUUUGCAUCU---------------------------------------- 2 0,2 ---------------------------------------------CGAAUGUUGCUCGGUGAAa--------------- 3 -1,-5 ---------------------------------------------CGAAUGUUGCUCGGUGAAC--------------- 20 -1,-4 ---------------------------------------------CGAAUGUUGCUCGGUGAACC-------------- 12 -1,-3 ---------------------------------------------CGAAUGUUGCUCGGUGAACCC------------- 6 -1,-2 ---------------------------------------------CGAAUGUUGCUCGGUGAACCCC------------ 17 -1,-1 ---------------------------------------------CGAAUGUUGCUCGGUGAACCCCU----------- 164 -1,0 ---------------------------------------------CGAAUGUUGCUCGGUGAACCCCUU---------- 63 -1,1 ---------------------------------------------CGAAUGUUGCUCGGUGAACCCCUUU--------- 3 -1,2 ----------------------------------------------GAAUGUUGCUCGGUGAAC--------------- 5 0,-4 ----------------------------------------------GAAUGUUGCUCGGUGAACC-------------- 6 0,-3 ----------------------------------------------GAAUGUUGCUCGGUGAACCa------------- 2 0,-3 ----------------------------------------------GAAUGUUGCUCGGUGAACCC------------- 15 0,-2 ----------------------------------------------GAAUGUUGCUCGGUGAACCCC------------ 55 0,-1 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCa----------- 6 0,-1 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCau---------- 2 0,-1 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCU----------- 436 0,0 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCUa---------- 12 0,0 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCUaa--------- 2 0,0 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCUau--------- 2 0,0 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCUU---------- 65 0,1 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCUUU--------- 14 0,2 -----------------------------------------------AAUGUUGCUCGGUGAACCCC------------ 2 1,-1 -----------------------------------------------AAUGUUGCUCGGUGAACCCCU----------- 31 1,0 >hsa-mir-410 3pM:50-70 Normal gguaccugagaagagguugucugugaugaguucgcuuuuauuaaugacgAAUAUAACACAGAUGGCCUGUuuucaguacc -------------------------------------------------AAUAUAACACAGAUGGCCUG----------- 2 0,-1 -------------------------------------------------AAUAUAACACAGAUGGCCUGU---------- 31 0,0 >hsa-mir-411 MA:16-36;mi:51-72 Normal ugguacuuggagagaUAGUAGACCGUAUAGCGUACGcuuuaucugugacgUAUGUAACACGGUCCACUAACCcucaguaucaaauccauccccgag --------------AUAGUAGACCGUAUAGCGUAa------------------------------------------------------------- 5 -1,-2 --------------AUAGUAGACCGUAUAGCGUAu------------------------------------------------------------- 2 -1,-2 --------------AUAGUAGACCGUAUAGCGUAC------------------------------------------------------------- 5 -1,-1 --------------AUAGUAGACCGUAUAGCGUACG------------------------------------------------------------ 51 -1,0 --------------AUAGUAGACCGUAUAGCGUACGa----------------------------------------------------------- 5 -1,0 ---------------UAGUAGACCGUAUAGCGUAC------------------------------------------------------------- 4 0,-1 ---------------UAGUAGACCGUAUAGCGUACG------------------------------------------------------------ 32 0,0 --------------------------------------------------UAUGUAACACGGUCCACUAAC------------------------- 3 0,-1 >hsa-mir-412 3pM:54-76 Normal cugggguacggggauggauggucgaccaguuggaaaguaauuguuucuaauguACUUCACCUGGUCCACUAGCCGUccguauccgcugcag ------------------UGGUCGACCAGUUGGAAAGU----------------------------------------------------- 2 ------------------UGGUCGACCAGUUGGAAAGUAA--------------------------------------------------- 4 ------------------UGGUCGACCAGUUGGAAAGUAAU-------------------------------------------------- 2 >hsa-mir-421 3pM:48-70 Normal gcacauuguaggccucauuaaauguuuguugaaugaaaaaaugaaucAUCAACAGACAUUAAUUGGGCGCcugcucugugaucuc -----------------------------------------------AUCAACAGACAUUAAUUGGGCG---------------- 2 0,-1 -----------------------------------------------AUCAACAGACAUUAAUUGGGCGC--------------- 6 0,0 >hsa-mir-423 5p:17-39;3p:53-75 Normal auaaaggaaguuaggcUGAGGGGCAGAGAGCGAGACUUUucuauuuuccaaaAGCUCGGUCUGAGGCCCCUCAGUcuugcuuccuaacccgcgc ---------------CUGAGGGGCAGAGAGCGAGACUU-------------------------------------------------------- 2 -1,-1 ---------------CUGAGGGGCAGAGAGCGAGACUUU------------------------------------------------------- 8 -1,0 ---------------CUGAGGGGCAGAGAGCGAGACUUUU------------------------------------------------------ 2 -1,1 ----------------UGAGGGGCAGAGAGCGAG------------------------------------------------------------ 32 0,-5 ----------------UGAGGGGCAGAGAGCGAGA----------------------------------------------------------- 197 0,-4 ----------------UGAGGGGCAGAGAGCGAGAa---------------------------------------------------------- 52 0,-4 ----------------UGAGGGGCAGAGAGCGAGAaa--------------------------------------------------------- 74 0,-4 ----------------UGAGGGGCAGAGAGCGAGAau--------------------------------------------------------- 6 0,-4 ----------------UGAGGGGCAGAGAGCGAGAu---------------------------------------------------------- 5 0,-4 ----------------UGAGGGGCAGAGAGCGAGAC---------------------------------------------------------- 139 0,-3 ----------------UGAGGGGCAGAGAGCGAGACa--------------------------------------------------------- 49 0,-3 ----------------UGAGGGGCAGAGAGCGAGACaa-------------------------------------------------------- 28 0,-3 ----------------UGAGGGGCAGAGAGCGAGACg--------------------------------------------------------- 2 0,-3 ----------------UGAGGGGCAGAGAGCGAGACU--------------------------------------------------------- 457 0,-2 ----------------UGAGGGGCAGAGAGCGAGACUaa------------------------------------------------------- 5 0,-2 ----------------UGAGGGGCAGAGAGCGAGACUau------------------------------------------------------- 3 0,-2 ----------------UGAGGGGCAGAGAGCGAGACUU-------------------------------------------------------- 359 0,-1 ----------------UGAGGGGCAGAGAGCGAGACUUa------------------------------------------------------- 31 0,-1 ----------------UGAGGGGCAGAGAGCGAGACUUaa------------------------------------------------------ 10 0,-1 ----------------UGAGGGGCAGAGAGCGAGACUUc------------------------------------------------------- 3 0,-1 ----------------UGAGGGGCAGAGAGCGAGACUUU------------------------------------------------------- 2822 0,0 ----------------UGAGGGGCAGAGAGCGAGACUUUa------------------------------------------------------ 17 0,0 ----------------UGAGGGGCAGAGAGCGAGACUUUg------------------------------------------------------ 2 0,0 ----------------UGAGGGGCAGAGAGCGAGACUUUU------------------------------------------------------ 487 0,1 ----------------UGAGGGGCAGAGAGCGAGACUUUUu----------------------------------------------------- 6 0,1 -----------------GAGGGGCAGAGAGCGAGA----------------------------------------------------------- 4 1,-4 -----------------GAGGGGCAGAGAGCGAGAa---------------------------------------------------------- 3 1,-4 -----------------GAGGGGCAGAGAGCGAGACU--------------------------------------------------------- 19 1,-2 -----------------GAGGGGCAGAGAGCGAGACUU-------------------------------------------------------- 14 1,-1 -----------------GAGGGGCAGAGAGCGAGACUUU------------------------------------------------------- 106 1,0 -----------------GAGGGGCAGAGAGCGAGACUUUU------------------------------------------------------ 16 1,1 ------------------AGGGGCAGAGAGCGAGACU--------------------------------------------------------- 2 2,-2 ------------------AGGGGCAGAGAGCGAGACUUU------------------------------------------------------- 2 2,0 ------------------AGGGGCAGAGAGCGAGACUUUU------------------------------------------------------ 13 2,1 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCU----------------------- 28 -1,-4 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUu---------------------- 2 -1,-4 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUuu--------------------- 3 -1,-4 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUC---------------------- 23 -1,-3 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCc--------------------- 2 -1,-3 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCu--------------------- 6 -1,-3 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCA--------------------- 46 -1,-2 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAa-------------------- 21 -1,-2 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAau------------------- 5 -1,-2 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAu-------------------- 6 -1,-2 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAuu------------------- 2 -1,-2 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAG-------------------- 75 -1,-1 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAGa------------------- 11 -1,-1 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAGc------------------- 2 -1,-1 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAGU------------------- 517 -1,0 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAGUa------------------ 3 -1,0 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAGUu------------------ 20 -1,0 ----------------------------------------------------AGCUCGGUCUGAGGCCCC------------------------ 8 0,-5 ----------------------------------------------------AGCUCGGUCUGAGGCCCCU----------------------- 29 0,-4 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUu---------------------- 5 0,-4 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUC---------------------- 138 0,-3 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCu--------------------- 13 0,-3 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCA--------------------- 123 0,-2 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAa-------------------- 51 0,-2 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAaa------------------- 31 0,-2 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAau------------------- 29 0,-2 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAu-------------------- 14 0,-2 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAuu------------------- 3 0,-2 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAG-------------------- 322 0,-1 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGa------------------- 167 0,-1 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGaa------------------ 58 0,-1 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGau------------------ 17 0,-1 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGc------------------- 29 0,-1 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGg------------------- 5 0,-1 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGU------------------- 4344 0,0 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGUa------------------ 145 0,0 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGUaa----------------- 16 0,0 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGUau----------------- 13 0,0 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGUg------------------ 8 0,0 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGUu------------------ 332 0,0 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGUuu----------------- 35 0,0 -----------------------------------------------------GCUCGGUCUGAGGCCCCUC---------------------- 3 1,-3 -----------------------------------------------------GCUCGGUCUGAGGCCCCUCAG-------------------- 4 1,-1 -----------------------------------------------------GCUCGGUCUGAGGCCCCUCAGU------------------- 95 1,0 -----------------------------------------------------GCUCGGUCUGAGGCCCCUCAGUa------------------ 2 1,0 -----------------------------------------------------GCUCGGUCUGAGGCCCCUCAGUu------------------ 2 1,0 >hsa-mir-424 MA:11-32;mi:48-68 Normal cgaggggauaCAGCAGCAAUUCAUGUUUUGAAguguucuaaaugguuCAAAACGUGAGGCGCUGCUAUacccccucguggggaagguagaaggugggg ---------ACAGCAGCAAUUCAUGUUUU--------------------------------------------------------------------- 2 -1,-3 ---------ACAGCAGCAAUUCAUGUUUUGA------------------------------------------------------------------- 56 -1,-1 ----------CAGCAGCAAUUCAUGUUU---------------------------------------------------------------------- 67 0,-4 ----------CAGCAGCAAUUCAUGUUUU--------------------------------------------------------------------- 134 0,-3 ----------CAGCAGCAAUUCAUGUUUUaa------------------------------------------------------------------- 14 0,-3 ----------CAGCAGCAAUUCAUGUUUUu-------------------------------------------------------------------- 2 0,-3 ----------CAGCAGCAAUUCAUGUUUUG-------------------------------------------------------------------- 412 0,-2 ----------CAGCAGCAAUUCAUGUUUUGc------------------------------------------------------------------- 9 0,-2 ----------CAGCAGCAAUUCAUGUUUUGg------------------------------------------------------------------- 7 0,-2 ----------CAGCAGCAAUUCAUGUUUUGu------------------------------------------------------------------- 16 0,-2 ----------CAGCAGCAAUUCAUGUUUUGA------------------------------------------------------------------- 9060 0,-1 ----------CAGCAGCAAUUCAUGUUUUGAc------------------------------------------------------------------ 4 0,-1 ----------CAGCAGCAAUUCAUGUUUUGAg------------------------------------------------------------------ 7 0,-1 ----------CAGCAGCAAUUCAUGUUUUGAu------------------------------------------------------------------ 18 0,-1 ----------CAGCAGCAAUUCAUGUUUUGAA------------------------------------------------------------------ 2267 0,0 ----------CAGCAGCAAUUCAUGUUUUGAAa----------------------------------------------------------------- 504 0,0 ----------CAGCAGCAAUUCAUGUUUUGAAaa---------------------------------------------------------------- 17 0,0 ----------CAGCAGCAAUUCAUGUUUUGAAau---------------------------------------------------------------- 2 0,0 ----------CAGCAGCAAUUCAUGUUUUGAAc----------------------------------------------------------------- 4 0,0 ----------CAGCAGCAAUUCAUGUUUUGAAu----------------------------------------------------------------- 142 0,0 ----------CAGCAGCAAUUCAUGUUUUGAAG----------------------------------------------------------------- 18 0,1 -----------AGCAGCAAUUCAUGUUUU--------------------------------------------------------------------- 5 1,-3 -----------AGCAGCAAUUCAUGUUUUG-------------------------------------------------------------------- 12 1,-2 -----------AGCAGCAAUUCAUGUUUUGA------------------------------------------------------------------- 225 1,-1 -----------AGCAGCAAUUCAUGUUUUGAA------------------------------------------------------------------ 79 1,0 -----------AGCAGCAAUUCAUGUUUUGAAa----------------------------------------------------------------- 21 1,0 -----------AGCAGCAAUUCAUGUUUUGAAu----------------------------------------------------------------- 8 1,0 -----------------------------------------------CAAAACGUGAGGCGCUGCU-------------------------------- 12 0,-2 -----------------------------------------------CAAAACGUGAGGCGCUGCUA------------------------------- 7 0,-1 -----------------------------------------------CAAAACGUGAGGCGCUGCUAa------------------------------ 5 0,-1 -----------------------------------------------CAAAACGUGAGGCGCUGCUAaa----------------------------- 2 0,-1 -----------------------------------------------CAAAACGUGAGGCGCUGCUAU------------------------------ 123 0,0 -----------------------------------------------CAAAACGUGAGGCGCUGCUAUA----------------------------- 25 0,1 -----------------------------------------------CAAAACGUGAGGCGCUGCUAUAa---------------------------- 10 0,1 -----------------------------------------------CAAAACGUGAGGCGCUGCUAUAu---------------------------- 2 0,1 ------------------------------------------------AAAACGUGAGGCGCUGCUAU------------------------------ 8 1,0 -------------------------------------------------AAACGUGAGGCGCUGCUAUAC---------------------------- 2 2,2 >hsa-mir-425 MA:14-36;mi:55-76 Normal gaaagcgcuuuggAAUGACACGAUCACUCCCGUUGAgugggcacccgagaagccAUCGGGAAUGUCGUGUCCGCCCagugcucuuuc -------------AAUGACACGAUCACUCCCG------------------------------------------------------- 8 0,-4 -------------AAUGACACGAUCACUCCCGU------------------------------------------------------ 17 0,-3 -------------AAUGACACGAUCACUCCCGUU----------------------------------------------------- 112 0,-2 -------------AAUGACACGAUCACUCCCGUUa---------------------------------------------------- 2 0,-2 -------------AAUGACACGAUCACUCCCGUUu---------------------------------------------------- 2 0,-2 -------------AAUGACACGAUCACUCCCGUUG---------------------------------------------------- 296 0,-1 -------------AAUGACACGAUCACUCCCGUUGu--------------------------------------------------- 29 0,-1 -------------AAUGACACGAUCACUCCCGUUGA--------------------------------------------------- 381 0,0 -------------AAUGACACGAUCACUCCCGUUGAa-------------------------------------------------- 9 0,0 -------------AAUGACACGAUCACUCCCGUUGAu-------------------------------------------------- 4 0,0 -------------AAUGACACGAUCACUCCCGUUGAG-------------------------------------------------- 220 0,1 -------------AAUGACACGAUCACUCCCGUUGAGa------------------------------------------------- 3 0,1 -------------AAUGACACGAUCACUCCCGUUGAGU------------------------------------------------- 270 0,2 --------------AUGACACGAUCACUCCCG------------------------------------------------------- 2 1,-4 --------------AUGACACGAUCACUCCCGU------------------------------------------------------ 2 1,-3 --------------AUGACACGAUCACUCCCGUUu---------------------------------------------------- 2 1,-2 --------------AUGACACGAUCACUCCCGUUG---------------------------------------------------- 16 1,-1 --------------AUGACACGAUCACUCCCGUUGA--------------------------------------------------- 41 1,0 --------------AUGACACGAUCACUCCCGUUGAG-------------------------------------------------- 73 1,1 --------------AUGACACGAUCACUCCCGUUGAGa------------------------------------------------- 9 1,1 --------------AUGACACGAUCACUCCCGUUGAGU------------------------------------------------- 143 1,2 --------------AUGACACGAUCACUCCCGUUGAGUu------------------------------------------------ 4 1,2 ---------------UGACACGAUCACUCCCGUUGAG-------------------------------------------------- 2 2,1 ---------------UGACACGAUCACUCCCGUUGAGU------------------------------------------------- 4 2,2 ----------------------------------------------------CCAUCGGGAAUGUCGUGUCCGu------------- 2 -2,-3 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCG-------------- 4 -1,-3 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGu------------- 2 -1,-3 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGC------------- 23 -1,-2 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGCa------------ 4 -1,-2 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGCu------------ 7 -1,-2 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGCC------------ 41 -1,-1 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGCCau---------- 3 -1,-1 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGCCu----------- 3 -1,-1 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGCCC----------- 3 -1,0 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGC------------- 6 0,-2 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCC------------ 7 0,-1 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCCu----------- 4 0,-1 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCCC----------- 17 0,0 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCCCu---------- 2 0,0 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCCCuu--------- 2 0,0 -------------------------------------------------------UCGGGAAUGUCGUGUCCGCCC----------- 2 1,0 >hsa-mir-4286 5pM:11-27 Normal uacuuauggcACCCCACUCCUGGUACCauagucauaaguuaggagauguuagagcugugaguaccaugacuuaagugugguggcuuaaacaug ----------ACCCCACUCCUGGUACCA----------------------------------------------------------------- 306 0,1 ----------ACCCCACUCCUGGUACCAa---------------------------------------------------------------- 88 0,1 ----------ACCCCACUCCUGGUACCAaa--------------------------------------------------------------- 38 0,1 ----------ACCCCACUCCUGGUACCAau--------------------------------------------------------------- 2 0,1 ----------ACCCCACUCCUGGUACCAU---------------------------------------------------------------- 29 0,2 ----------ACCCCACUCCUGGUACCAUu--------------------------------------------------------------- 2 0,2 ----------ACCCCACUCCUGGUACCAUAa-------------------------------------------------------------- 4 0,3 >hsa-mir-429 3pM:51-72 Normal cgccggccgaugggcgucuuaccagacaugguuagaccuggcccucugucUAAUACUGUCUGGUAAAACCGUccauccgcugc --------------------------------------------------UAAUACUGUCUGGUAAAACC------------- 5 0,-2 --------------------------------------------------UAAUACUGUCUGGUAAAACCG------------ 71 0,-1 --------------------------------------------------UAAUACUGUCUGGUAAAACCGa----------- 9 0,-1 --------------------------------------------------UAAUACUGUCUGGUAAAACCGU----------- 186 0,0 --------------------------------------------------UAAUACUGUCUGGUAAAACCGUa---------- 9 0,0 ---------------------------------------------------AAUACUGUCUGGUAAAACCG------------ 4 1,-1 ---------------------------------------------------AAUACUGUCUGGUAAAACCGU----------- 4 1,0 ----------------------------------------------------AUACUGUCUGGUAAAACCGU----------- 2 2,0 >hsa-mir-431 MA:20-40;mi:63-84 Normal uccugcuuguccugcgaggUGUCUUGCAGGCCGUCAUGCAggccacacugacgguaacguugCAGGUCGUCUUGCAGGGCUUCUcgcaagacgacauccucaucaccaacgacg -------------------UGUCUUGCAGGCCGUCAUGC--------------------------------------------------------------------------- 2 0,-1 -------------------UGUCUUGCAGGCCGUCAUGCA-------------------------------------------------------------------------- 9 0,0 -------------------UGUCUUGCAGGCCGUCAUGCAGG------------------------------------------------------------------------ 2 0,2 ------------------------------------------------------------UGCAGGUCGUCUUGCAGGGCUU-------------------------------- 2 -2,-2 --------------------------------------------------------------CAGGUCGUCUUGCAGGGCUUCU------------------------------ 3 0,0 >hsa-mir-432 MA:14-36;mi:62-82 Normal ugacuccuccaggUCUUGGAGUAGGUCAUUGGGUGGauccucuauuuccuuacgugggccaCUGGAUGGCUCCUCCAUGUCUuggaguagauca -------------UCUUGGAGUAGGUCAUUGG-------------------------------------------------------------- 2 0,-4 -------------UCUUGGAGUAGGUCAUUGGGU------------------------------------------------------------ 12 0,-2 -------------UCUUGGAGUAGGUCAUUGGGUG----------------------------------------------------------- 10 0,-1 -------------UCUUGGAGUAGGUCAUUGGGUGa---------------------------------------------------------- 6 0,-1 -------------UCUUGGAGUAGGUCAUUGGGUGu---------------------------------------------------------- 19 0,-1 -------------UCUUGGAGUAGGUCAUUGGGUGG---------------------------------------------------------- 4 0,0 ------------------------------------------------------------ACUGGAUGGCUCCUCCAUGUCU------------ 2 -1,0 >hsa-mir-4326 5pM:11-30 Normal gcugcucugcUGUUCCUCUGUCUCCCAGACucuggguggauggagcaggucgggggcca ----------UGUUCCUCUGUCUCCCAGACUCU-------------------------- 2 0,3 >hsa-mir-433 3pM:64-85 Normal ccggggagaaguacggugagccugucauuauucagagaggcuagauccucuguguugagaaggAUCAUGAUGGGCUCCUCGGUGUucuccagg ---------------------------------------------------------------AUCAUGAUGGGCUCCUCGGUGU-------- 39 0,0 ---------------------------------------------------------------AUCAUGAUGGGCUCCUCGGUGUa------- 2 0,0 ---------------------------------------------------------------AUCAUGAUGGGCUCCUCGGUGUU------- 3 0,1 >hsa-mir-4421 3pM:43-64 Normal cugggucuccuuucugcugagaguugaacacuuguugggacaACCUGUCUGUGGAAAGGAGCUAccuac ------------------------------------------ACCUGUCUGUGGAAAGGAGCUA----- 2 0,0 -------------------------------------------CCUGUCUGUGGAAAGGAGCUAu---- 2 1,0 >hsa-mir-4423 5p:13-34;3p:49-69 Normal aucauguacugcAGUUGCCUUUUUGUUCCCAUGCuguuuaagccuagcAUAGGCACCAAAAAGCAACAAcaguaugugaa ------------AGUUGCCUUUUUGUUCCCAUGC---------------------------------------------- 2 0,0 >hsa-mir-4429 5pM:7-26 Normal agggagAAAAGCUGGGCUGAGAGGCGacuggugucuaauuuguuugucucuccaacucagacugccuggccca ------AAAAGCUGGGCUGAGAGG------------------------------------------------- 79 0,-2 >hsa-mir-4454 5pM:3-22 Normal ccGGAUCCGAGUCACGGCACCAaauuucaugcguguccgugugaagagaccacca ----AUCCGAGUCACGGCACCA--------------------------------- 52 2,0 >hsa-mir-4466 5pM:5-22 Normal acgcGGGUGCGGGCCGGCGGGGuagaagccacccggcccggcccggcccggcga ----GGGUGCGGGCCGGCGGGGU------------------------------- 2 0,1 >hsa-mir-4484 3pM:64-83 Normal ggguuuccucugccuuuuuuuccaaugaaaauaacgaaaccuguuauuucccauugagggggaAAAAGGCGGGAGAAGCCCCA ---------------------------------------------------------------AAAAGGCGGGAGAAGCCCC- 4 0,-1 >hsa-mir-4488 5pM:4-21 Normal gguAGGGGGCGGGCUCCGGCGcugggaccccacuaggguggcgccuuggccccgccccgccc ---AGGGGGCGGGCUCCGGCG----------------------------------------- 17 0,0 ---AGGGGGCGGGCUCCGGCGg---------------------------------------- 2 0,0 >hsa-mir-4508 5pM:9-25 Normal aggacccaGCGGGGCUGGGCGCGCGgagcagcgcugggugcagcgccugcgccggcagcugcaagggccg -------AGCGGGGCUGGGCGCGCG--------------------------------------------- 2 -1,0 -------AGCGGGGCUGGGCGCGCGc-------------------------------------------- 2 -1,0 >hsa-mir-450a-1 5pM:18-39 Normal aaacgauacuaaacuguUUUUGCGAUGUGUUCCUAAUAUgcacuauaaauauauugggaacauuuugcauguauaguuuuguaucaauaua -----------------UUUUGCGAUGUGUUCCUAA------------------------------------------------------- 3 0,-3 -----------------UUUUGCGAUGUGUUCCUAAa------------------------------------------------------ 2 0,-3 -----------------UUUUGCGAUGUGUUCCUAAaa----------------------------------------------------- 2 0,-3 -----------------UUUUGCGAUGUGUUCCUAAU------------------------------------------------------ 104 0,-2 -----------------UUUUGCGAUGUGUUCCUAAUu----------------------------------------------------- 2 0,-2 -----------------UUUUGCGAUGUGUUCCUAAUA----------------------------------------------------- 23 0,-1 -----------------UUUUGCGAUGUGUUCCUAAUAa---------------------------------------------------- 7 0,-1 -----------------UUUUGCGAUGUGUUCCUAAUAU---------------------------------------------------- 68 0,0 -----------------UUUUGCGAUGUGUUCCUAAUAUa--------------------------------------------------- 2 0,0 -----------------UUUUGCGAUGUGUUCCUAAUAUG--------------------------------------------------- 2 0,1 ----------------------------------------------------AUUGGGAACAUUUUGCAUGUAU----------------- 23 >hsa-mir-450a-2 5pM:23-44 Normal ccaaagaaagaugcuaaacuauUUUUGCGAUGUGUUCCUAAUAUguaauauaaauguauuggggacauuuugcauucauaguuuuguaucaauaauaugg ----------------------UUUUGCGAUGUGUUCCUAA----------------------------------------------------------- 3 0,-3 ----------------------UUUUGCGAUGUGUUCCUAAa---------------------------------------------------------- 2 0,-3 ----------------------UUUUGCGAUGUGUUCCUAAaa--------------------------------------------------------- 2 0,-3 ----------------------UUUUGCGAUGUGUUCCUAAU---------------------------------------------------------- 104 0,-2 ----------------------UUUUGCGAUGUGUUCCUAAUu--------------------------------------------------------- 2 0,-2 ----------------------UUUUGCGAUGUGUUCCUAAUA--------------------------------------------------------- 23 0,-1 ----------------------UUUUGCGAUGUGUUCCUAAUAa-------------------------------------------------------- 7 0,-1 ----------------------UUUUGCGAUGUGUUCCUAAUAU-------------------------------------------------------- 68 0,0 ----------------------UUUUGCGAUGUGUUCCUAAUAUa------------------------------------------------------- 2 0,0 ----------------------UUUUGCGAUGUGUUCCUAAUAUG------------------------------------------------------- 2 0,1 ---------------------------------------------------------AUUGGGGACAUUUUGCAUUCAU--------------------- 6 ----------------------------------------------------------UUGGGGACAUUUUGCAUUCAU--------------------- 3 >hsa-mir-450b 5p:11-32;3p:48-69 Normal gcagaauuauUUUUGCAAUAUGUUCCUGAAUAuguaauauaaguguaUUGGGAUCAUUUUGCAUCCAUAguuuuguau ----------UUUUGCAAUAUGUUCCUGAAU----------------------------------------------- 53 0,-1 ----------UUUUGCAAUAUGUUCCUGAAUA---------------------------------------------- 19 0,0 ----------UUUUGCAAUAUGUUCCUGAAUAa--------------------------------------------- 2 0,0 >hsa-mir-451 5pM:17-38 Normal cuugggaauggcaaggAAACCGUUACCAUUACUGAGUUuaguaaugguaaugguucucuugcuauacccaga ----------------AAACCGUUACCAUUACUG-------------------------------------- 1422 0,-4 ----------------AAACCGUUACCAUUACUGc------------------------------------- 5 0,-4 ----------------AAACCGUUACCAUUACUGu------------------------------------- 2 0,-4 ----------------AAACCGUUACCAUUACUGuu------------------------------------ 4 0,-4 ----------------AAACCGUUACCAUUACUGA------------------------------------- 1388 0,-3 ----------------AAACCGUUACCAUUACUGAa------------------------------------ 17 0,-3 ----------------AAACCGUUACCAUUACUGAau----------------------------------- 31 0,-3 ----------------AAACCGUUACCAUUACUGAc------------------------------------ 17 0,-3 ----------------AAACCGUUACCAUUACUGAu------------------------------------ 26 0,-3 ----------------AAACCGUUACCAUUACUGAuu----------------------------------- 100 0,-3 ----------------AAACCGUUACCAUUACUGAG------------------------------------ 11776 0,-2 ----------------AAACCGUUACCAUUACUGAGa----------------------------------- 132 0,-2 ----------------AAACCGUUACCAUUACUGAGaa---------------------------------- 2 0,-2 ----------------AAACCGUUACCAUUACUGAGau---------------------------------- 161 0,-2 ----------------AAACCGUUACCAUUACUGAGc----------------------------------- 201 0,-2 ----------------AAACCGUUACCAUUACUGAGg----------------------------------- 118 0,-2 ----------------AAACCGUUACCAUUACUGAGU----------------------------------- 51764 0,-1 ----------------AAACCGUUACCAUUACUGAGUa---------------------------------- 39 0,-1 ----------------AAACCGUUACCAUUACUGAGUaa--------------------------------- 2 0,-1 ----------------AAACCGUUACCAUUACUGAGUau--------------------------------- 6 0,-1 ----------------AAACCGUUACCAUUACUGAGUc---------------------------------- 105 0,-1 ----------------AAACCGUUACCAUUACUGAGUg---------------------------------- 48 0,-1 ----------------AAACCGUUACCAUUACUGAGUU---------------------------------- 69885 0,0 ----------------AAACCGUUACCAUUACUGAGUUa--------------------------------- 55 0,0 ----------------AAACCGUUACCAUUACUGAGUUaa-------------------------------- 10 0,0 ----------------AAACCGUUACCAUUACUGAGUUc--------------------------------- 60 0,0 ----------------AAACCGUUACCAUUACUGAGUUg--------------------------------- 11 0,0 ----------------AAACCGUUACCAUUACUGAGUUU--------------------------------- 39745 0,1 ----------------AAACCGUUACCAUUACUGAGUUUg-------------------------------- 2 0,1 ----------------AAACCGUUACCAUUACUGAGUUUu-------------------------------- 6 0,1 ----------------AAACCGUUACCAUUACUGAGUUUA-------------------------------- 808 0,2 ----------------AAACCGUUACCAUUACUGAGUUUAa------------------------------- 8 0,2 ----------------AAACCGUUACCAUUACUGAGUUUAc------------------------------- 3 0,2 ----------------AAACCGUUACCAUUACUGAGUUUAu------------------------------- 105 0,2 ----------------AAACCGUUACCAUUACUGAGUUUAG------------------------------- 1985 0,3 -----------------AACCGUUACCAUUACUGA------------------------------------- 60 1,-3 -----------------AACCGUUACCAUUACUGAa------------------------------------ 2 1,-3 -----------------AACCGUUACCAUUACUGAau----------------------------------- 2 1,-3 -----------------AACCGUUACCAUUACUGAu------------------------------------ 5 1,-3 -----------------AACCGUUACCAUUACUGAuu----------------------------------- 11 1,-3 -----------------AACCGUUACCAUUACUGAG------------------------------------ 293 1,-2 -----------------AACCGUUACCAUUACUGAGc----------------------------------- 4 1,-2 -----------------AACCGUUACCAUUACUGAGU----------------------------------- 1540 1,-1 -----------------AACCGUUACCAUUACUGAGUc---------------------------------- 5 1,-1 -----------------AACCGUUACCAUUACUGAGUU---------------------------------- 2045 1,0 -----------------AACCGUUACCAUUACUGAGUUa--------------------------------- 3 1,0 -----------------AACCGUUACCAUUACUGAGUUU--------------------------------- 1180 1,1 -----------------AACCGUUACCAUUACUGAGUUUA-------------------------------- 19 1,2 -----------------AACCGUUACCAUUACUGAGUUUAu------------------------------- 7 1,2 -----------------AACCGUUACCAUUACUGAGUUUAuu------------------------------ 2 1,2 -----------------AACCGUUACCAUUACUGAGUUUAG------------------------------- 54 1,3 -----------------AACCGUUACCAUUACUGAGUUUAGU------------------------------ 34 1,4 ------------------ACCGUUACCAUUACUGAGUU---------------------------------- 7 2,0 ------------------ACCGUUACCAUUACUGAGUUU--------------------------------- 3 2,1 >hsa-mir-452 MA:14-35;mi:58-79 Normal gcuaagcacuuacAACUGUUUGCAGAGGAAACUGAgacuuuguaacuaugucucaguCUCAUCUGCAAAGAAGUAAGUGcuuugc ------------CAACUGUUUGCAGAGGAAACUGA-------------------------------------------------- 3 -1,0 -------------AACUGUUUGCAGAGGAAA------------------------------------------------------ 2 0,-4 -------------AACUGUUUGCAGAGGAAAC----------------------------------------------------- 3 0,-3 -------------AACUGUUUGCAGAGGAAACU---------------------------------------------------- 14 0,-2 -------------AACUGUUUGCAGAGGAAACUG--------------------------------------------------- 152 0,-1 -------------AACUGUUUGCAGAGGAAACUGu-------------------------------------------------- 81 0,-1 -------------AACUGUUUGCAGAGGAAACUGA-------------------------------------------------- 1181 0,0 -------------AACUGUUUGCAGAGGAAACUGAa------------------------------------------------- 53 0,0 -------------AACUGUUUGCAGAGGAAACUGAu------------------------------------------------- 7 0,0 -------------AACUGUUUGCAGAGGAAACUGAG------------------------------------------------- 453 0,1 -------------AACUGUUUGCAGAGGAAACUGAGu------------------------------------------------ 38 0,1 -------------AACUGUUUGCAGAGGAAACUGAGA------------------------------------------------ 246 0,2 -------------AACUGUUUGCAGAGGAAACUGAGAa----------------------------------------------- 7 0,2 -------------AACUGUUUGCAGAGGAAACUGAGAu----------------------------------------------- 2 0,2 --------------ACUGUUUGCAGAGGAAACUG--------------------------------------------------- 2 1,-1 --------------ACUGUUUGCAGAGGAAACUGA-------------------------------------------------- 41 1,0 --------------ACUGUUUGCAGAGGAAACUGAG------------------------------------------------- 10 1,1 --------------ACUGUUUGCAGAGGAAACUGAGA------------------------------------------------ 13 1,2 ---------------CUGUUUGCAGAGGAAACUGA-------------------------------------------------- 2 2,0 ---------------CUGUUUGCAGAGGAAACUGAG------------------------------------------------- 6 2,1 ---------------CUGUUUGCAGAGGAAACUGAGA------------------------------------------------ 25 2,2 ---------------------------------------------------CUCAGUCUCAUCUGCAAAGA-------------- 15 -6,-8 ---------------------------------------------------CUCAGUCUCAUCUGCAAAGAA------------- 4 -6,-7 ---------------------------------------------------CUCAGUCUCAUCUGCAAAGAAG------------ 10 -6,-6 ---------------------------------------------------CUCAGUCUCAUCUGCAAAGAAGU----------- 4 -6,-5 ----------------------------------------------------UCAGUCUCAUCUGCAAAG--------------- 2 -5,-9 ----------------------------------------------------UCAGUCUCAUCUGCAAAGAA------------- 5 -5,-7 ----------------------------------------------------UCAGUCUCAUCUGCAAAGAAa------------ 4 -5,-7 ----------------------------------------------------UCAGUCUCAUCUGCAAAGAAG------------ 24 -5,-6 ----------------------------------------------------UCAGUCUCAUCUGCAAAGAAGU----------- 170 -5,-5 ----------------------------------------------------UCAGUCUCAUCUGCAAAGAAGUu---------- 2 -5,-5 >hsa-mir-4521 5pM:4-25 Normal ucgGCUAAGGAAGUCCUGUGCUCAGuuuuguagcaucaaaacuaggauuucucuuguuac ---GCUAAGGAAGUCCUGUGCUCAGU---------------------------------- 7 0,1 ---GCUAAGGAAGUCCUGUGCUCAGUU--------------------------------- 2 0,2 ---GCUAAGGAAGUCCUGUGCUCAGUUU-------------------------------- 102 0,3 >hsa-mir-4524 MA:6-27;mi:42-63 Normal gaacgAUAGCAGCAUGAACCUGUCUCAcugcagaauuauuuUGAGACAGGCUUAUGCUGCUAUccuuca -------AGCAGCAUGAACCUGUCUCACU---------------------------------------- 4 2,2 -----------------------------------------UGAGACAGGCUUAUGCUGCU-------- 4 0,-2 -----------------------------------------UGAGACAGGCUUAUGCUGCUA------- 2 0,-1 -----------------------------------------UGAGACAGGCUUAUGCUGCUAU------ 14 0,0 >hsa-mir-4532 5pM:6-22 Normal acagaCCCCGGGGAGCCCGGCGgugaagcuccugguauccugggugucuga -----CCCCGGGGAGCCCGGCGG---------------------------- 200 0,1 -----CCCCGGGGAGCCCGGCGGg--------------------------- 75 0,1 >hsa-mir-454 mi:24-45;MA:64-86 Normal ucuguuuaucaccagauccuagaACCCUAUCAAUAUUGUCUCUGCuguguaaauaguucugagUAGUGCAAUAUUGCUUAUAGGGUuuugguguuuggaaagaacaaugggcagg ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAG-------------------------------- 2 0,-3 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGG------------------------------- 2 0,-2 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGGG------------------------------ 6 0,-1 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGGGU----------------------------- 11 0,0 ----------------------------------------------------------------AGUGCAAUAUUGCUUAUAGGGUU---------------------------- 2 1,1 >hsa-mir-455 5p:16-37;3p:54-74 Normal ucccuggcgugagggUAUGUGCCUUUGGACUACAUCGuggaagccagcaccauGCAGUCCAUGGGCAUAUACACuugccucaaggccuaugucauc --------------GUAUGUGCCUUUGGACUACA-------------------------------------------------------------- 17 -1,-3 --------------GUAUGUGCCUUUGGACUACAU------------------------------------------------------------- 48 -1,-2 --------------GUAUGUGCCUUUGGACUACAUCG----------------------------------------------------------- 4 -1,0 ---------------UAUGUGCCUUUGGACUACA-------------------------------------------------------------- 3 0,-3 ---------------UAUGUGCCUUUGGACUACAUCG----------------------------------------------------------- 174 0,0 ---------------UAUGUGCCUUUGGACUACAUCGa---------------------------------------------------------- 4 0,0 ---------------UAUGUGCCUUUGGACUACAUCGU---------------------------------------------------------- 11 0,1 ---------------UAUGUGCCUUUGGACUACAUCGUG--------------------------------------------------------- 2 0,2 ----------------AUGUGCCUUUGGACUACAUCG----------------------------------------------------------- 3 1,0 ----------------AUGUGCCUUUGGACUACAUCGU---------------------------------------------------------- 5 1,1 -----------------UGUGCCUUUGGACUACAUCGUG--------------------------------------------------------- 5 2,2 -----------------UGUGCCUUUGGACUACAUCGUGa-------------------------------------------------------- 2 2,2 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUAC------------------------ 15 -2,-2 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUACA----------------------- 14 -2,-1 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUACAC---------------------- 7 -2,0 ----------------------------------------------------UGCAGUCCAUGGGCAUAUAC------------------------ 2 -1,-2 ----------------------------------------------------UGCAGUCCAUGGGCAUAUACA----------------------- 3 -1,-1 ----------------------------------------------------UGCAGUCCAUGGGCAUAUACAC---------------------- 5 -1,0 -----------------------------------------------------GCAGUCCAUGGGCAUAUA------------------------- 2 0,-3 -----------------------------------------------------GCAGUCCAUGGGCAUAUAC------------------------ 8 0,-2 -----------------------------------------------------GCAGUCCAUGGGCAUAUACA----------------------- 19 0,-1 -----------------------------------------------------GCAGUCCAUGGGCAUAUACAa---------------------- 2 0,-1 -----------------------------------------------------GCAGUCCAUGGGCAUAUACAC---------------------- 44 0,0 -----------------------------------------------------GCAGUCCAUGGGCAUAUACACa--------------------- 6 0,0 -----------------------------------------------------GCAGUCCAUGGGCAUAUACACc--------------------- 26 0,0 -----------------------------------------------------GCAGUCCAUGGGCAUAUACACU--------------------- 44 0,1 ------------------------------------------------------CAGUCCAUGGGCAUAUACAC---------------------- 4 1,0 ------------------------------------------------------CAGUCCAUGGGCAUAUACACUU-------------------- 2 1,2 >hsa-mir-4636 5pM:10-31 Normal uagauucagAACUCGUGUUCAAAGCCUUUAGcccagcaaugggagagugcuaaaggcuucaagcacgaguucugaaucua ---------AACUCGUGUUCAAAGCCUUUAGC------------------------------------------------ 2 0,1 >hsa-mir-4662b 3pM:50-71 Normal cacaauuucuauuuagccaauugucuaucuuuaggcauucagaauagcuAAAGAUGGACAAUUGGCUAAAUagacacugug -------------------------------------------------AAAGAUGGACAAUUGGCUAAAU---------- 2 0,0 >hsa-mir-4707 5p:10-32;3p:52-73 Normal gguuccggaGCCCCGGCGCGGGCGGGUUCUGGgguguagacgcugcuggccAGCCCGCCCCAGCCGAGGUUCUcggcacc ---------------------------------------------------AGCCCGCCCCAGCCGAGGUU--------- 2 0,-2 ---------------------------------------------------AGCCCGCCCCAGCCGAGGUUCU------- 2 0,0 >hsa-mir-4743 5pM:11-33 Normal ccucuccugcUGGCCGGAUGGGACAGGAGGCAUgaaugagccaucuuuccaaugccuuucugucuuuucugguccagguguggcaaaggg ----------UGGCCGGAUGGGACAGGAGaa----------------------------------------------------------- 2 0,-4 >hsa-mir-483 5p:8-29;3p:48-68 Normal gagggggAAGACGGGAGGAAAGAAGGGAGugguuccaucacgccuccUCACUCCUCUCCUCCCGUCUUcuccucuc -------AAGACGGGAGGAAAGAAGGaa------------------------------------------------ 2 0,-3 -------AAGACGGGAGGAAAGAAGGG------------------------------------------------- 4 0,-2 -------AAGACGGGAGGAAAGAAGGGu------------------------------------------------ 2 0,-2 -------AAGACGGGAGGAAAGAAGGGA------------------------------------------------ 69 0,-1 -------AAGACGGGAGGAAAGAAGGGAa----------------------------------------------- 41 0,-1 -------AAGACGGGAGGAAAGAAGGGAaa---------------------------------------------- 27 0,-1 -------AAGACGGGAGGAAAGAAGGGAau---------------------------------------------- 3 0,-1 -------AAGACGGGAGGAAAGAAGGGAu----------------------------------------------- 2 0,-1 -------AAGACGGGAGGAAAGAAGGGAG----------------------------------------------- 150 0,0 -------AAGACGGGAGGAAAGAAGGGAGa---------------------------------------------- 39 0,0 -------AAGACGGGAGGAAAGAAGGGAGU---------------------------------------------- 7 0,1 --------AGACGGGAGGAAAGAAGGGAG----------------------------------------------- 2 1,0 --------AGACGGGAGGAAAGAAGGGAGU---------------------------------------------- 5 1,1 --------AGACGGGAGGAAAGAAGGGAGUGG-------------------------------------------- 2 1,3 -----------------------------------------------UCACUCCUCUCCUCCCGUCU--------- 3 0,-1 -----------------------------------------------UCACUCCUCUCCUCCCGUCUU-------- 3 0,0 -----------------------------------------------UCACUCCUCUCCUCCCGUCUUu------- 4 0,0 -----------------------------------------------UCACUCCUCUCCUCCCGUCUUC------- 6 0,1 ------------------------------------------------CACUCCUCUCCUCCCGUCUUuu------ 2 1,0 ------------------------------------------------CACUCCUCUCCUCCCGUCUUC------- 4 1,1 ------------------------------------------------CACUCCUCUCCUCCCGUCUUCc------ 3 1,1 ------------------------------------------------CACUCCUCUCCUCCCGUCUUCU------ 22 1,2 >hsa-mir-484 5pM:8-29 Normal agccucgUCAGGCUCAGUCCCCUCCCGAUaaaccccuaaauagggacuuucccggggggugacccuggcuuuuuuggcg -------UCAGGCUCAGUCCCCUCCCG---------------------------------------------------- 28 0,-2 -------UCAGGCUCAGUCCCCUCCCGu--------------------------------------------------- 4 0,-2 -------UCAGGCUCAGUCCCCUCCCGuu-------------------------------------------------- 16 0,-2 -------UCAGGCUCAGUCCCCUCCCGA--------------------------------------------------- 111 0,-1 -------UCAGGCUCAGUCCCCUCCCGAa-------------------------------------------------- 13 0,-1 -------UCAGGCUCAGUCCCCUCCCGAaa------------------------------------------------- 16 0,-1 -------UCAGGCUCAGUCCCCUCCCGAau------------------------------------------------- 10 0,-1 -------UCAGGCUCAGUCCCCUCCCGAU-------------------------------------------------- 234 0,0 -------UCAGGCUCAGUCCCCUCCCGAUu------------------------------------------------- 42 0,0 -------UCAGGCUCAGUCCCCUCCCGAUuu------------------------------------------------ 6 0,0 -------UCAGGCUCAGUCCCCUCCCGAUA------------------------------------------------- 36 0,1 -------UCAGGCUCAGUCCCCUCCCGAUAu------------------------------------------------ 2 0,1 -------UCAGGCUCAGUCCCCUCCCGAUAA------------------------------------------------ 5 0,2 --------CAGGCUCAGUCCCCUCCCGAU-------------------------------------------------- 3 1,0 >hsa-mir-485 5p:9-30;3p:46-67 Normal acuuggagAGAGGCUGGCCGUGAUGAAUUCgauucaucaaagcgaGUCAUACACGGCUCUCCUCUCUuuuagu --------AGAGGCUGGCCGUGAUGAA---------------------------------------------- 4 0,-3 --------AGAGGCUGGCCGUGAUGAAa--------------------------------------------- 4 0,-3 --------AGAGGCUGGCCGUGAUGAAU--------------------------------------------- 53 0,-2 --------AGAGGCUGGCCGUGAUGAAUU-------------------------------------------- 4 0,-1 --------AGAGGCUGGCCGUGAUGAAUUC------------------------------------------- 27 0,0 --------AGAGGCUGGCCGUGAUGAAUUCu------------------------------------------ 2 0,0 --------AGAGGCUGGCCGUGAUGAAUUCG------------------------------------------ 51 0,1 --------AGAGGCUGGCCGUGAUGAAUUCGu----------------------------------------- 2 0,1 ---------GAGGCUGGCCGUGAUGAAU--------------------------------------------- 2 1,-2 ---------GAGGCUGGCCGUGAUGAAUUCG------------------------------------------ 2 1,1 ---------------------------------------------GUCAUACACGGCUCUCCUCUC------- 2 0,-1 ---------------------------------------------GUCAUACACGGCUCUCCUCUCa------ 2 0,-1 ---------------------------------------------GUCAUACACGGCUCUCCUCUCc------ 2 0,-1 ---------------------------------------------GUCAUACACGGCUCUCCUCUCU------ 10 0,0 >hsa-mir-486 5p:4-25;3p:46-66 Normal gcaUCCUGUACUGAGCUGCCCCGAGgcccuucaugcugcccagcuCGGGGCAGCUCAGUACAGGAUac --AUCCUGUACUGAGCUGCCCCGA-------------------------------------------- 3 -1,-1 ---UCCUGUACUGAGCUGCCC----------------------------------------------- 5 0,-4 ---UCCUGUACUGAGCUGCCCC---------------------------------------------- 2 0,-3 ---UCCUGUACUGAGCUGCCCCG--------------------------------------------- 54 0,-2 ---UCCUGUACUGAGCUGCCCCGc-------------------------------------------- 5 0,-2 ---UCCUGUACUGAGCUGCCCCGA-------------------------------------------- 620 0,-1 ---UCCUGUACUGAGCUGCCCCGAa------------------------------------------- 27 0,-1 ---UCCUGUACUGAGCUGCCCCGAaa------------------------------------------ 3 0,-1 ---UCCUGUACUGAGCUGCCCCGAc------------------------------------------- 3 0,-1 ---UCCUGUACUGAGCUGCCCCGAu------------------------------------------- 10 0,-1 ---UCCUGUACUGAGCUGCCCCGAG------------------------------------------- 1084 0,0 ---UCCUGUACUGAGCUGCCCCGAGa------------------------------------------ 397 0,0 ---UCCUGUACUGAGCUGCCCCGAGaa----------------------------------------- 4 0,0 ---UCCUGUACUGAGCUGCCCCGAGau----------------------------------------- 3 0,0 ---UCCUGUACUGAGCUGCCCCGAGc------------------------------------------ 2 0,0 ---UCCUGUACUGAGCUGCCCCGAGu------------------------------------------ 110 0,0 ---UCCUGUACUGAGCUGCCCCGAGG------------------------------------------ 2 0,1 -----CUGUACUGAGCUGCCCCGAG------------------------------------------- 9 2,0 -----CUGUACUGAGCUGCCCCGAGu------------------------------------------ 2 2,0 ---------------------------------------------CGGGGCAGCUCAGUACAGGA--- 8 0,-1 ---------------------------------------------CGGGGCAGCUCAGUACAGGAU-- 23 0,0 >hsa-mir-487a 3pM:49-70 Normal gguacuugaagagugguuaucccugcuguguucgcuuaauuuaugacgAAUCAUACAGGGACAUCCAGUUuuucaguauc ------------GUGGUUAUCCCUGCUGUGUUCG---------------------------------------------- 18 ------------------------------------------------AAUCAUACAGGGACAUCCAGUU---------- 8 0,0 >hsa-mir-487b 3pM:51-72 Normal uugguacuuggagagugguuaucccuguccuguucguuuugcucaugucgAAUCGUACAGGGUCAUCCACUUuuucaguaucaa --------------------------------------------------AAUCGUACAGGGUCAUCCACU------------- 29 0,-1 --------------------------------------------------AAUCGUACAGGGUCAUCCACUU------------ 112 0,0 --------------------------------------------------AAUCGUACAGGGUCAUCCACUUa----------- 3 0,0 --------------------------------------------------AAUCGUACAGGGUCAUCCACUUU----------- 26 0,1 ---------------------------------------------------AUCGUACAGGGUCAUCCACUU------------ 2 1,0 ---------------------------------------------------AUCGUACAGGGUCAUCCACUUU----------- 20 1,1 ----------------------------------------------------UCGUACAGGGUCAUCCACUUU----------- 5 2,1 ----------------------------------------------------UCGUACAGGGUCAUCCACUUUU---------- 2 2,2 >hsa-mir-488 mi:14-34;MA:52-72 Normal gagaaucaucucuCCCAGAUAAUGGCACUCUCAAacaaguuuccaaauuguUUGAAAGGCUAUUUCUUGGUCagaugacucuc -------------CCCAGAUAAUGGCACUCUCAA------------------------------------------------- 2 0,0 --------------------------------------------------UUUGAAAGGCUAUUUCUUGGUC----------- 2 -1,0 ---------------------------------------------------UUGAAAGGCUAUUUCUUGGUaa---------- 2 0,-1 ---------------------------------------------------UUGAAAGGCUAUUUCUUGGUC----------- 18 0,0 ---------------------------------------------------UUGAAAGGCUAUUUCUUGGUCu---------- 88 0,0 ---------------------------------------------------UUGAAAGGCUAUUUCUUGGUCuu--------- 5 0,0 ---------------------------------------------------UUGAAAGGCUAUUUCUUGGUCA---------- 7 0,1 ----------------------------------------------------UGAAAGGCUAUUUCUUGGUCu---------- 2 1,0 >hsa-mir-489 3pM:52-73 Normal guggcagcuugguggucguaugugugacgccauuuacuugaaccuuuaggaGUGACAUCACAUAUACGGCAGCuaaacugcuac ---------------------------------------------------GUGACAUCACAUAUACGGCAG------------ 2 0,-1 ---------------------------------------------------GUGACAUCACAUAUACGGCAGC----------- 4 0,0 >hsa-mir-491 5p:16-37;3p:50-71 Normal uugacuuagcuggguAGUGGGGAACCCUUCCAUGAGGaguagaacacucCUUAUGCAAGAUUCCCUUCUACcuggcuggguugg ---------------AGUGGGGAACCCUUCCAUG-------------------------------------------------- 2 0,-3 ---------------AGUGGGGAACCCUUCCAUGAG------------------------------------------------ 5 0,-1 ---------------AGUGGGGAACCCUUCCAUGAGa----------------------------------------------- 5 0,-1 ---------------AGUGGGGAACCCUUCCAUGAGu----------------------------------------------- 3 0,-1 ---------------AGUGGGGAACCCUUCCAUGAGG----------------------------------------------- 81 0,0 ---------------AGUGGGGAACCCUUCCAUGAGGA---------------------------------------------- 99 0,1 ---------------AGUGGGGAACCCUUCCAUGAGGAa--------------------------------------------- 20 0,1 ---------------AGUGGGGAACCCUUCCAUGAGGAG--------------------------------------------- 4 0,2 ----------------GUGGGGAACCCUUCCAUGAGG----------------------------------------------- 2 1,0 -----------------UGGGGAACCCUUCCAUGAGGAGU-------------------------------------------- 2 2,3 >hsa-mir-493 mi:16-37;MA:57-78 Normal cuggccuccagggcuUUGUACAUGGUAGGCUUUCAUUcauucguuugcacauucggUGAAGGUCUACUGUGUGCCAGGcccugugccag ---------------UUGUACAUGGUAGGCUUUCAUU---------------------------------------------------- 6 0,0 --------------------------------------------------------UGAAGGUCUACUGUGUGCCAG------------ 6 0,-1 --------------------------------------------------------UGAAGGUCUACUGUGUGCCAGu----------- 2 0,-1 --------------------------------------------------------UGAAGGUCUACUGUGUGCCAGG----------- 5 0,0 --------------------------------------------------------UGAAGGUCUACUGUGUGCCAGGu---------- 2 0,0 >hsa-mir-494 3pM:48-69 Normal gauacucgaaggagagguuguccguguugucuucucuuuauuuaugaUGAAACAUACACGGGAAACCUCuuuuuuaguauc --------------AGGUUGUCCGUGUUGUCUUCU---------------------------------------------- 3 -----------------------------------------------UGAAACAUACACGGGAAAC--------------- 2 0,-3 -----------------------------------------------UGAAACAUACACGGGAAACCU------------- 8 0,-1 -----------------------------------------------UGAAACAUACACGGGAAACCUC------------ 13 0,0 -----------------------------------------------UGAAACAUACACGGGAAACCUCa----------- 4 0,0 -----------------------------------------------UGAAACAUACACGGGAAACCUCU----------- 129 0,1 -----------------------------------------------UGAAACAUACACGGGAAACCUCUU---------- 2 0,2 ------------------------------------------------GAAACAUACACGGGAAACCUCU----------- 4 1,1 >hsa-mir-495 3pM:50-71 Normal ugguaccugaaaagaaguugcccauguuauuuucgcuuuauaugugacgAAACAAACAUGGUGCACUUCUUuuucgguauca -------------------------------------------------AAACAAACAUGGUGCACUUCU------------ 14 0,-1 -------------------------------------------------AAACAAACAUGGUGCACUUCUU----------- 138 0,0 -------------------------------------------------AAACAAACAUGGUGCACUUCUUU---------- 100 0,1 --------------------------------------------------AACAAACAUGGUGCACUUCUU----------- 6 1,0 --------------------------------------------------AACAAACAUGGUGCACUUCUUU---------- 25 1,1 >hsa-mir-497 MA:24-44;mi:64-85 Normal ccaccccgguccugcucccgcccCAGCAGCACACUGUGGUUUGUacggcacuguggccacgucCAAACCACACUGUGGUGUUAGAgcgagggugggggaggcaccgccgagg ----------------------CCAGCAGCACACUGUGGUUUGU-------------------------------------------------------------------- 8 -1,0 -----------------------CAGCAGCACACUGUGGUU----------------------------------------------------------------------- 107 0,-3 -----------------------CAGCAGCACACUGUGGUUaa--------------------------------------------------------------------- 3 0,-3 -----------------------CAGCAGCACACUGUGGUUU---------------------------------------------------------------------- 111 0,-2 -----------------------CAGCAGCACACUGUGGUUUa--------------------------------------------------------------------- 9 0,-2 -----------------------CAGCAGCACACUGUGGUUUaa-------------------------------------------------------------------- 4 0,-2 -----------------------CAGCAGCACACUGUGGUUUau-------------------------------------------------------------------- 24 0,-2 -----------------------CAGCAGCACACUGUGGUUUu--------------------------------------------------------------------- 15 0,-2 -----------------------CAGCAGCACACUGUGGUUUuu-------------------------------------------------------------------- 31 0,-2 -----------------------CAGCAGCACACUGUGGUUUG--------------------------------------------------------------------- 325 0,-1 -----------------------CAGCAGCACACUGUGGUUUGa-------------------------------------------------------------------- 344 0,-1 -----------------------CAGCAGCACACUGUGGUUUGaa------------------------------------------------------------------- 42 0,-1 -----------------------CAGCAGCACACUGUGGUUUGc-------------------------------------------------------------------- 48 0,-1 -----------------------CAGCAGCACACUGUGGUUUGg-------------------------------------------------------------------- 17 0,-1 -----------------------CAGCAGCACACUGUGGUUUGU-------------------------------------------------------------------- 15615 0,0 -----------------------CAGCAGCACACUGUGGUUUGUg------------------------------------------------------------------- 7 0,0 -----------------------CAGCAGCACACUGUGGUUUGUu------------------------------------------------------------------- 170 0,0 -----------------------CAGCAGCACACUGUGGUUUGUuu------------------------------------------------------------------ 7 0,0 -----------------------CAGCAGCACACUGUGGUUUGUA------------------------------------------------------------------- 2138 0,1 -----------------------CAGCAGCACACUGUGGUUUGUAa------------------------------------------------------------------ 837 0,1 -----------------------CAGCAGCACACUGUGGUUUGUAaa----------------------------------------------------------------- 11 0,1 -----------------------CAGCAGCACACUGUGGUUUGUAau----------------------------------------------------------------- 4 0,1 -----------------------CAGCAGCACACUGUGGUUUGUAg------------------------------------------------------------------ 55 0,1 -----------------------CAGCAGCACACUGUGGUUUGUAu------------------------------------------------------------------ 417 0,1 -----------------------CAGCAGCACACUGUGGUUUGUAuu----------------------------------------------------------------- 2 0,1 -----------------------CAGCAGCACACUGUGGUUUGUAC------------------------------------------------------------------ 89 0,2 -----------------------CAGCAGCACACUGUGGUUUGUACG----------------------------------------------------------------- 3 0,3 ------------------------AGCAGCACACUGUGGUUU---------------------------------------------------------------------- 5 1,-2 ------------------------AGCAGCACACUGUGGUUUau-------------------------------------------------------------------- 4 1,-2 ------------------------AGCAGCACACUGUGGUUUuu-------------------------------------------------------------------- 2 1,-2 ------------------------AGCAGCACACUGUGGUUUG--------------------------------------------------------------------- 15 1,-1 ------------------------AGCAGCACACUGUGGUUUGa-------------------------------------------------------------------- 14 1,-1 ------------------------AGCAGCACACUGUGGUUUGU-------------------------------------------------------------------- 1132 1,0 ------------------------AGCAGCACACUGUGGUUUGUu------------------------------------------------------------------- 6 1,0 ------------------------AGCAGCACACUGUGGUUUGUA------------------------------------------------------------------- 160 1,1 ------------------------AGCAGCACACUGUGGUUUGUAa------------------------------------------------------------------ 100 1,1 ------------------------AGCAGCACACUGUGGUUUGUAaa----------------------------------------------------------------- 4 1,1 ------------------------AGCAGCACACUGUGGUUUGUAg------------------------------------------------------------------ 2 1,1 ------------------------AGCAGCACACUGUGGUUUGUAu------------------------------------------------------------------ 19 1,1 ------------------------AGCAGCACACUGUGGUUUGUAC------------------------------------------------------------------ 364 1,2 ------------------------AGCAGCACACUGUGGUUUGUACa----------------------------------------------------------------- 10 1,2 ------------------------AGCAGCACACUGUGGUUUGUACu----------------------------------------------------------------- 2 1,2 ------------------------AGCAGCACACUGUGGUUUGUACG----------------------------------------------------------------- 5 1,3 -------------------------GCAGCACACUGUGGUUUGU-------------------------------------------------------------------- 9 2,0 -------------------------GCAGCACACUGUGGUUUGUAa------------------------------------------------------------------ 2 2,1 -------------------------GCAGCACACUGUGGUUUGUAC------------------------------------------------------------------ 3 2,2 -------------------------------------------------------------UCCAAACCACACUGUGGUGUU------------------------------ 4 -2,-3 -------------------------------------------------------------UCCAAACCACACUGUGGUGUUAG---------------------------- 2 -2,-1 --------------------------------------------------------------CCAAACCACACUGUGGUGUU------------------------------ 9 -1,-3 --------------------------------------------------------------CCAAACCACACUGUGGUGUUg----------------------------- 3 -1,-3 --------------------------------------------------------------CCAAACCACACUGUGGUGUUAu---------------------------- 3 -1,-2 --------------------------------------------------------------CCAAACCACACUGUGGUGUUAG---------------------------- 4 -1,-1 --------------------------------------------------------------CCAAACCACACUGUGGUGUUAGu--------------------------- 2 -1,-1 --------------------------------------------------------------CCAAACCACACUGUGGUGUUAGA--------------------------- 12 -1,0 ---------------------------------------------------------------CAAACCACACUGUGGUGUU------------------------------ 33 0,-3 ---------------------------------------------------------------CAAACCACACUGUGGUGUUA----------------------------- 2 0,-2 ---------------------------------------------------------------CAAACCACACUGUGGUGUUAGu--------------------------- 2 0,-1 ---------------------------------------------------------------CAAACCACACUGUGGUGUUAGA--------------------------- 20 0,0 >hsa-mir-499 5p:33-53;3p:70-91 Normal gcccuguccccugugccuugggcgggcggcugUUAAGACUUGCAGUGAUGUUUaacuccucuccacgugAACAUCACAGCAAGUCUGUGCUgcuucccgucccuacgcugccugggcagggu --------------------------------UUAAGACUUGCAGUGAUGUU---------------------------------------------------------------------- 2 0,-1 --------------------------------UUAAGACUUGCAGUGAUGUUU--------------------------------------------------------------------- 60 0,0 --------------------------------UUAAGACUUGCAGUGAUGUUUA-------------------------------------------------------------------- 7 0,1 --------------------------------------------------------------------GAACAUCACAGCAAGUCUGUGa-------------------------------- 2 -1,-2 --------------------------------------------------------------------GAACAUCACAGCAAGUCUGUGC-------------------------------- 2 -1,-1 ---------------------------------------------------------------------AACAUCACAGCAAGUCUGUGCU------------------------------- 2 0,0 >hsa-mir-500a MA:13-35;mi:52-73 Normal gcucccccucucUAAUCCUUGCUACCUGGGUGAGAgugcugucugaaugcaAUGCACCUGGGCAAGGAUUCUGagagcgagagc ------------UAAUCCUUGCUACCUGGGUGAG-------------------------------------------------- 6 0,-1 ------------UAAUCCUUGCUACCUGGGUGAGu------------------------------------------------- 3 0,-1 ------------UAAUCCUUGCUACCUGGGUGAGA------------------------------------------------- 15 0,0 ------------UAAUCCUUGCUACCUGGGUGAGAGU----------------------------------------------- 3 0,2 --------------------------------------------------AAUGCACCUGGGCAAGGA---------------- 2 -1,-5 --------------------------------------------------AAUGCACCUGGGCAAGGAU--------------- 14 -1,-4 --------------------------------------------------AAUGCACCUGGGCAAGGAUU-------------- 82 -1,-3 --------------------------------------------------AAUGCACCUGGGCAAGGAUUC------------- 96 -1,-2 --------------------------------------------------AAUGCACCUGGGCAAGGAUUCc------------ 2 -1,-2 --------------------------------------------------AAUGCACCUGGGCAAGGAUUCg------------ 2 -1,-2 --------------------------------------------------AAUGCACCUGGGCAAGGAUUCU------------ 35 -1,-1 ---------------------------------------------------AUGCACCUGGGCAAGGAUU-------------- 8 0,-3 ---------------------------------------------------AUGCACCUGGGCAAGGAUUC------------- 3 0,-2 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCU------------ 43 0,-1 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCUu----------- 2 0,-1 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCUG----------- 17 0,0 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCUGu---------- 25 0,0 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCUGA---------- 43 0,1 >hsa-mir-500b 5pM:11-28 Normal cccccucucuAAUCCUUGCUACCUGGGUgagagugcuuucugaaugcagugcacccaggcaaggauucugcaaggggga ---------UAAUCCUUGCUACCUGGGUGAG------------------------------------------------ 6 -1,3 ---------UAAUCCUUGCUACCUGGGUGAGu----------------------------------------------- 3 -1,3 ---------UAAUCCUUGCUACCUGGGUGAGA----------------------------------------------- 15 -1,4 >hsa-mir-501 5p:14-35;3p:51-72 Normal gcucuuccucucuAAUCCUUUGUCCCUGGGUGAGAgugcuuucugaaugcAAUGCACCCGGGCAAGGAUUCUgagagggugagc -------------AAUCCUUUGUCCCUGGGUGAaa------------------------------------------------- 2 0,-2 -------------AAUCCUUUGUCCCUGGGUGAGA------------------------------------------------- 25 0,0 -------------AAUCCUUUGUCCCUGGGUGAGAa------------------------------------------------ 2 0,0 -------------AAUCCUUUGUCCCUGGGUGAGAG------------------------------------------------ 10 0,1 -------------AAUCCUUUGUCCCUGGGUGAGAGU----------------------------------------------- 23 0,2 --------------------------------------------------AAUGCACCCGGGCAAGGAU--------------- 4 0,-3 --------------------------------------------------AAUGCACCCGGGCAAGGAUU-------------- 24 0,-2 --------------------------------------------------AAUGCACCCGGGCAAGGAUUC------------- 15 0,-1 --------------------------------------------------AAUGCACCCGGGCAAGGAUUCa------------ 2 0,-1 --------------------------------------------------AAUGCACCCGGGCAAGGAUUCc------------ 7 0,-1 --------------------------------------------------AAUGCACCCGGGCAAGGAUUCU------------ 112 0,0 --------------------------------------------------AAUGCACCCGGGCAAGGAUUCUG----------- 2 0,1 >hsa-mir-502 5p:16-36;3p:52-73 Normal ugcucccccucucuaAUCCUUGCUAUCUGGGUGCUAgugcuggcucaaugcAAUGCACCUGGGCAAGGAUUCAgagagggggagcu ---------------------------------------------------AAUGCACCUGGGCAAGGA----------------- 2 0,-4 ---------------------------------------------------AAUGCACCUGGGCAAGGAU---------------- 14 0,-3 ---------------------------------------------------AAUGCACCUGGGCAAGGAUU--------------- 82 0,-2 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUC-------------- 96 0,-1 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUCc------------- 2 0,-1 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUCg------------- 2 0,-1 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUCA------------- 162 0,0 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUCAa------------ 2 0,0 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUCAu------------ 2 0,0 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUCAG------------ 31 0,1 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUCAGu----------- 22 0,1 ----------------------------------------------------AUGCACCUGGGCAAGGAUU--------------- 8 1,-2 ----------------------------------------------------AUGCACCUGGGCAAGGAUUC-------------- 3 1,-1 >hsa-mir-503 5pM:6-28 Normal ugcccUAGCAGCGGGAACAGUUCUGCAGugagcgaucggugcucugggguauuguuuccgcugccagggua ----CUAGCAGCGGGAACAGUUCUGCAG------------------------------------------- 2 -1,0 -----UAGCAGCGGGAACAGUUC------------------------------------------------ 5 0,-5 -----UAGCAGCGGGAACAGUUCU----------------------------------------------- 18 0,-4 -----UAGCAGCGGGAACAGUUCUaa--------------------------------------------- 5 0,-4 -----UAGCAGCGGGAACAGUUCUG---------------------------------------------- 21 0,-3 -----UAGCAGCGGGAACAGUUCUGa--------------------------------------------- 4 0,-3 -----UAGCAGCGGGAACAGUUCUGaa-------------------------------------------- 5 0,-3 -----UAGCAGCGGGAACAGUUCUGCA-------------------------------------------- 14 0,-1 -----UAGCAGCGGGAACAGUUCUGCAG------------------------------------------- 88 0,0 ------AGCAGCGGGAACAGUUCUGCAG------------------------------------------- 3 1,0 >hsa-mir-504 5pM:13-34 Normal gcugcuguugggAGACCCUGGUCUGCACUCUAUCuguauucuuacugaagggagugcagggcaggguuucccauacagagggc ------------AGACCCUGGUCUGCACUCU---------------------------------------------------- 6 0,-3 ------------AGACCCUGGUCUGCACUCUAU-------------------------------------------------- 45 0,-1 ------------AGACCCUGGUCUGCACUCUAUC------------------------------------------------- 34 0,0 ------------AGACCCUGGUCUGCACUCUAUCa------------------------------------------------ 3 0,0 -------------GACCCUGGUCUGCACUCUAU-------------------------------------------------- 7 1,-1 -------------GACCCUGGUCUGCACUCUAUC------------------------------------------------- 6 1,0 -------------GACCCUGGUCUGCACUCUAUCaa----------------------------------------------- 2 1,0 >hsa-mir-505 mi:15-36;MA:51-72 Normal gaugcacccaguggGGGAGCCAGGAAGUAUUGAUGUuucugccaguuuagCGUCAACACUUGCUGGUUUCCUcucuggagcauc --------------GGGAGCCAGGAAGUAUUGAUGUU----------------------------------------------- 11 0,1 --------------------------------------------------CGUCAACACUUGCUGGUUU--------------- 9 0,-3 --------------------------------------------------CGUCAACACUUGCUGGUUUC-------------- 7 0,-2 --------------------------------------------------CGUCAACACUUGCUGGUUUCC------------- 14 0,-1 --------------------------------------------------CGUCAACACUUGCUGGUUUCCU------------ 50 0,0 --------------------------------------------------CGUCAACACUUGCUGGUUUCCUC----------- 22 0,1 --------------------------------------------------CGUCAACACUUGCUGGUUUCCUCU---------- 35 0,2 ---------------------------------------------------GUCAACACUUGCUGGUUU--------------- 2 1,-3 ---------------------------------------------------GUCAACACUUGCUGGUUUC-------------- 5 1,-2 ---------------------------------------------------GUCAACACUUGCUGGUUUCC------------- 3 1,-1 ---------------------------------------------------GUCAACACUUGCUGGUUUCCU------------ 32 1,0 ---------------------------------------------------GUCAACACUUGCUGGUUUCCUC----------- 13 1,1 ---------------------------------------------------GUCAACACUUGCUGGUUUCCUCa---------- 6 1,1 ---------------------------------------------------GUCAACACUUGCUGGUUUCCUCU---------- 81 1,2 ----------------------------------------------------UCAACACUUGCUGGUUUCCU------------ 2 2,0 ----------------------------------------------------UCAACACUUGCUGGUUUCCUCU---------- 17 2,2 >hsa-mir-511-1 5pM:16-36 Normal caauagacacccaucGUGUCUUUUGCUCUGCAGUCAguaaauauuuuuuugugaauguguagcaaaagacagaauggugguccauug ---------------GUGUCUUUUGCUCUGCAGUCA--------------------------------------------------- 19 0,0 ---------------GUGUCUUUUGCUCUGCAGUCAGU------------------------------------------------- 2 0,2 -----------------------------------------------------AAUGUGUAGCAAAAGACAG--------------- 2 -----------------------------------------------------AAUGUGUAGCAAAAGACAGA-------------- 48 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAA------------- 36 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAAa------------ 17 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAAU------------ 36 ------------------------------------------------------AUGUGUAGCAAAAGACAGAA------------- 2 ------------------------------------------------------AUGUGUAGCAAAAGACAGAAU------------ 2 --------------------------------------------------------GUGUAGCAAAAGACAGAA------------- 2 >hsa-mir-511-2 5pM:16-36 Normal caauagacacccaucGUGUCUUUUGCUCUGCAGUCAguaaauauuuuuuugugaauguguagcaaaagacagaauggugguccauug ---------------GUGUCUUUUGCUCUGCAGUCA--------------------------------------------------- 19 0,0 ---------------GUGUCUUUUGCUCUGCAGUCAGU------------------------------------------------- 2 0,2 -----------------------------------------------------AAUGUGUAGCAAAAGACAG--------------- 2 -----------------------------------------------------AAUGUGUAGCAAAAGACAGA-------------- 48 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAA------------- 36 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAAa------------ 17 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAAU------------ 36 ------------------------------------------------------AUGUGUAGCAAAAGACAGAA------------- 2 ------------------------------------------------------AUGUGUAGCAAAAGACAGAAU------------ 2 --------------------------------------------------------GUGUAGCAAAAGACAGAA------------- 2 >hsa-mir-512-1 5p:14-36;3p:51-72 Normal ucucagucuguggCACUCAGCCUUGAGGGCACUUUCuggugccagaaugaAAGUGCUGUCAUAGCUGAGGUCcaaugacugagg --------------------------------------------------AAGUGCUGUCAUAGCUGAGGUCu----------- 7 0,0 >hsa-mir-512-2 5p:20-42;3p:57-78 Normal gguacuucucagucuguggCACUCAGCCUUGAGGGCACUUUCuggugccagaaugaAAGUGCUGUCAUAGCUGAGGUCcaaugacugaggcgagcacc --------------------------------------------------------AAGUGCUGUCAUAGCUGAGGUCu------------------- 7 0,0 >hsa-mir-514-1 3pM:59-79 Normal aacauguugucugugguacccuacucuggagagugacaaucauguauaauuaaauuugAUUGACACUUCUGUGAGUAGAguaacgcaugacacguacg ----------------------------------------------------------AUUGACACUUCUGUGAGUAG-------------------- 2 0,-1 ----------------------------------------------------------AUUGACACUUCUGUGAGUAGA------------------- 6 0,0 >hsa-mir-514-2 3pM:54-74 Normal guugucugugguacccuacucuggagagugacaaucauguauaacuaaauuugAUUGACACUUCUGUGAGUAGAguaacgcaugacac -----------------------------------------------------AUUGACACUUCUGUGAGUAG--------------- 2 0,-1 -----------------------------------------------------AUUGACACUUCUGUGAGUAGA-------------- 6 0,0 >hsa-mir-514-3 3pM:54-74 Normal guugucugugguacccuacucuggagagugacaaucauguauaacuaaauuugAUUGACACUUCUGUGAGUAGAguaacgcaugacac -----------------------------------------------------AUUGACACUUCUGUGAGUAG--------------- 2 0,-1 -----------------------------------------------------AUUGACACUUCUGUGAGUAGA-------------- 6 0,0 >hsa-mir-515-1 5p:14-37;3p:51-72 Normal ucucaugcagucaUUCUCCAAAAGAAAGCACUUUCUGuugucugaaagcaGAGUGCCUUCUUUUGGAGCGUUacuguuugaga -------------UUCUCCAAAAGAAAGCACUUUCU----------------------------------------------- 2 0,-1 --------------------------------------------------GAGUGCCUUCUUUUGGAGCGU------------ 2 0,-1 --------------------------------------------------GAGUGCCUUCUUUUGGAGCGUU----------- 3 0,0 >hsa-mir-515-2 5p:14-37;3p:51-72 Normal ucucaugcagucaUUCUCCAAAAGAAAGCACUUUCUGuugucugaaagcaGAGUGCCUUCUUUUGGAGCGUUacuguuugaga -------------UUCUCCAAAAGAAAGCACUUUCU----------------------------------------------- 2 0,-1 --------------------------------------------------GAGUGCCUUCUUUUGGAGCGU------------ 2 0,-1 --------------------------------------------------GAGUGCCUUCUUUUGGAGCGUU----------- 3 0,0 >hsa-mir-516a-1 5p:16-38;3p:61-78 Normal ucucaggcugugaccUUCUCGAGGAAAGAAGCACUUUCuguugucugaaagaaaagaaagUGCUUCCUUUCAGAGGGUuacgguuugaga ---------------UUCUCGAGGAAAGAAGCACUU------------------------------------------------------ 2 0,-2 ---------------UUCUCGAGGAAAGAAGCACUUU----------------------------------------------------- 2 0,-1 ---------------UUCUCGAGGAAAGAAGCACUUUC---------------------------------------------------- 2 0,0 >hsa-mir-516a-2 5p:16-38;3p:61-78 Normal ucucagguugugaccUUCUCGAGGAAAGAAGCACUUUCuguugucugaaagaaaagaaagUGCUUCCUUUCAGAGGGUuacgguuugaga ---------------UUCUCGAGGAAAGAAGCACUU------------------------------------------------------ 2 0,-2 ---------------UUCUCGAGGAAAGAAGCACUUU----------------------------------------------------- 2 0,-1 ---------------UUCUCGAGGAAAGAAGCACUUUC---------------------------------------------------- 2 0,0 >hsa-mir-516b-1 MA:16-37;mi:61-78 Normal ucucaggcugugaccAUCUGGAGGUAAGAAGCACUUUcuguuuugugaaagaaaagaaagUGCUUCCUUUCAGAGGGUuacucuuugaga ---------------AUCUGGAGGUAAGAAGCACUUUC---------------------------------------------------- 3 0,1 >hsa-mir-517a mi:15-36;MA:54-75 Normal ucucaggcagugacCCUCUAGAUGGAAGCACUGUCUguuguauaaaagaaaagAUCGUGCAUCCCUUUAGAGUGUuacuguuugaga -----------------------------------------------------AUCGUGCAUCCCUUUAGAGUGU------------ 11 0,0 >hsa-mir-517b mi:6-27;MA:44-65 Normal gugacCCUCUAGAUGGAAGCACUGUCUguugucuaagaaaagaUCGUGCAUCCCUUUAGAGUGUUac ------------------------------------------AUCGUGCAUCCCUUUAGAGUGU--- 11 -1,-1 >hsa-mir-517c mi:20-41;MA:57-78 Normal gaagaucucaggcagugacCCUCUAGAUGGAAGCACUGUCUguugucuaagaaaagAUCGUGCAUCCUUUUAGAGUGUuacuguuugagaaaauc --------------------------------------------------------AUCGUGCAUCCUUUUAGAGUGU----------------- 2 0,0 >hsa-mir-518a-1 5p:14-33;3p:51-72 Normal ucucaagcugugaCUGCAAAGGGAAGCCCUUUCuguugucugaaagaagaGAAAGCGCUUCCCUUUGCUGGAuuacgguuugaga -------------CUGCAAAGGGAAGCCCUUUCU--------------------------------------------------- 3 0,1 --------------------------------------------------GAAAGCGCUUCCCUUUGCUGGA------------- 2 0,0 >hsa-mir-518a-2 5p:16-35;3p:53-74 Normal ucucaagcuguggguCUGCAAAGGGAAGCCCUUUCuguugucuaaaagaagaGAAAGCGCUUCCCUUUGCUGGAuuacgguuugaga ---------------CUGCAAAGGGAAGCCCUUUCU--------------------------------------------------- 3 0,1 ----------------------------------------------------GAAAGCGCUUCCCUUUGCUGGA------------- 2 0,0 >hsa-mir-518b 3pM:51-72 Normal ucaugcuguggcccuccagagggaagcgcuuucuguugucugaaagaaaaCAAAGCGCUCCCCUUUAGAGGUuuacgguuuga --------------------------------------------------CAAAGCGCUCCCCUUUAGAGG------------ 2 0,-1 >hsa-mir-518c mi:24-46;MA:62-84 Normal gcgagaagaucucaugcugugacUCUCUGGAGGGAAGCACUUUCUGuugucugaaagaaaaCAAAGCGCUUCUCUUUAGAGUGUuacgguuugagaaaagc -------------------------------------------------------------CAAAGCGCUUCUCUUUAGAGUG------------------ 2 0,-1 >hsa-mir-518e mi:16-37;MA:54-74 Normal ucucaggcugugaccCUCUAGAGGGAAGCGCUUUCUGuuggcuaaaagaaaagAAAGCGCUUCCCUUCAGAGUGuuaacgcuuugaga ---------------CUCUAGAGGGAAGCGCUUUCU---------------------------------------------------- 2 0,-1 -----------------------------------------------------AAAGCGCUUCCCUUCAGAGUG-------------- 2 0,0 -----------------------------------------------------AAAGCGCUUCCCUUCAGAGUGU------------- 4 0,1 >hsa-mir-519a-1 mi:15-36;MA:53-74 Normal cucaggcugugacaCUCUAGAGGGAAGCGCUUUCUGuugucugaaagaaaggAAAGUGCAUCCUUUUAGAGUGUuacuguuugag --------------CUCUAGAGGGAAGCGCUUUCU-------------------------------------------------- 2 0,-1 ----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGU----------- 7 0,0 >hsa-mir-519a-2 3pM:54-75 Normal ucucaggcugugucccucuacagggaagcgcuuucuguugucugaaagaaaggAAAGUGCAUCCUUUUAGAGUGUuacuguuugaga -----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGU------------ 7 0,0 >hsa-mir-519b 5p:13-34;3p:51-72 Normal caugcugugaccCUCUAGAGGGAAGCGCUUUCUGuugucugaaagaaaagAAAGUGCAUCCUUUUAGAGGUUuacuguuug ------------CUCUAGAGGGAAGCGCUUUCU------------------------------------------------ 2 0,-1 >hsa-mir-519c 5p:16-37;3p:54-75 Normal ucucagccugugaccCUCUAGAGGGAAGCGCUUUCUGuugucugaaagaaaagAAAGUGCAUCUUUUUAGAGGAUuacaguuugaga ---------------CUCUAGAGGGAAGCGCUUUCU--------------------------------------------------- 2 0,-1 >hsa-mir-520c 5p:16-37;3p:54-75 Normal ucucaggcugucgucCUCUAGAGGGAAGCACUUUCUGuugucugaaagaaaagAAAGUGCUUCCUUUUAGAGGGUuaccguuugaga -----------------------------------------------------AAAGUGCUUCCUUUUAGAGGGU------------ 2 0,0 >hsa-mir-520d 5p:16-35;3p:54-75 Normal ucucaagcugugaguCUACAAAGGGAAGCCCUUUCuguugucuaaaagaaaagAAAGUGCUUCUCUUUGGUGGGUuacgguuugaga ---------------CUACAAAGGGAAGCCCUUUCU--------------------------------------------------- 3 0,1 >hsa-mir-522 mi:16-37;MA:54-75 Normal ucucaggcuguguccCUCUAGAGGGAAGCGCUUUCUGuugucugaaagaaaagAAAAUGGUUCCCUUUAGAGUGUuacgcuuugaga ---------------CUCUAGAGGGAAGCGCUUUCU--------------------------------------------------- 2 0,-1 -----------------------------------------------------AAAAUGGUUCCCUUUAGAGUGU------------ 2 0,0 >hsa-mir-523 mi:16-37;MA:53-75 Normal ucucaugcugugaccCUCUAGAGGGAAGCGCUUUCUGuugucugaaagaaaaGAACGCGCUUCCCUAUAGAGGGUuacccuuugaga ---------------CUCUAGAGGGAAGCGCUUUCU--------------------------------------------------- 2 0,-1 >hsa-mir-527 5pM:14-33 Normal ucucaagcugugaCUGCAAAGGGAAGCCCUUUCuguugucuaaaagaaaagaaagugcuucccuuuggugaauuacgguuugaga -------------CUGCAAAGGGAAGCCCUUUCU--------------------------------------------------- 3 0,1 >hsa-mir-532 5p:20-41;3p:57-78 Normal cgacuugcuuucucuccucCAUGCCUUGAGUGUAGGACCGUuggcaucuuaauuacCCUCCCACACCCAAGGCUUGCAaaaaagcgagccu -------------------CAUGCCUUGAGUGUAGGAC----------------------------------------------------- 2 0,-3 -------------------CAUGCCUUGAGUGUAGGACa---------------------------------------------------- 2 0,-3 -------------------CAUGCCUUGAGUGUAGGACCG--------------------------------------------------- 11 0,-1 -------------------CAUGCCUUGAGUGUAGGACCGa-------------------------------------------------- 9 0,-1 -------------------CAUGCCUUGAGUGUAGGACCGg-------------------------------------------------- 2 0,-1 -------------------CAUGCCUUGAGUGUAGGACCGU-------------------------------------------------- 364 0,0 -------------------CAUGCCUUGAGUGUAGGACCGUa------------------------------------------------- 16 0,0 -------------------CAUGCCUUGAGUGUAGGACCGUU------------------------------------------------- 8 0,1 --------------------AUGCCUUGAGUGUAGGACCGU-------------------------------------------------- 29 1,0 --------------------------------------------------------CCUCCCACACCCAAGGCUUG--------------- 6 0,-2 --------------------------------------------------------CCUCCCACACCCAAGGCUUGu-------------- 2 0,-2 --------------------------------------------------------CCUCCCACACCCAAGGCUUGC-------------- 108 0,-1 --------------------------------------------------------CCUCCCACACCCAAGGCUUGCA------------- 149 0,0 --------------------------------------------------------CCUCCCACACCCAAGGCUUGCAu------------ 4 0,0 --------------------------------------------------------CCUCCCACACCCAAGGCUUGCAA------------ 16 0,1 ---------------------------------------------------------CUCCCACACCCAAGGCUUGCA------------- 12 1,0 >hsa-mir-539 5pM:9-30 Normal auacuugaGGAGAAAUUAUCCUUGGUGUGUucgcuuuauuuaugaugaaucauacaaggacaauuucuuuuugaguau --------GGAGAAAUUAUCCUUGGUGUGU------------------------------------------------ 5 0,0 --------GGAGAAAUUAUCCUUGGUGUGUU----------------------------------------------- 6 0,1 ------------------------------------------------AUCAUACAAGGACAAUUUCUUU-------- 37 --------------------------------------------------CAUACAAGGACAAUUUCUUUU------- 3 ---------------------------------------------------AUACAAGGACAAUUUCUUUUU------ 5 ---------------------------------------------------AUACAAGGACAAUUUCUUUUUGA---- 2 >hsa-mir-542 5p:16-38;3p:53-74 Normal cagaucucagacaucUCGGGGAUCAUCAUGUCACGAGAuaccagugugcacuUGUGACAGAUUGAUAACUGAAAggucugggagccacucaucuuca --------------CUCGGGGAUCAUCAUGUCACG-------------------------------------------------------------- 2 -1,-3 --------------CUCGGGGAUCAUCAUGUCACGA------------------------------------------------------------- 3 -1,-2 ---------------UCGGGGAUCAUCAUGUCACG-------------------------------------------------------------- 2 0,-3 ---------------UCGGGGAUCAUCAUGUCACGA------------------------------------------------------------- 25 0,-2 ---------------UCGGGGAUCAUCAUGUCACGAG------------------------------------------------------------ 15 0,-1 ---------------UCGGGGAUCAUCAUGUCACGAGu----------------------------------------------------------- 4 0,-1 ---------------UCGGGGAUCAUCAUGUCACGAGA----------------------------------------------------------- 21 0,0 ----------------CGGGGAUCAUCAUGUCACGA------------------------------------------------------------- 3 1,-2 ---------------------------------------------------UUGUGACAGAUUGAUAACUG-------------------------- 3 -1,-3 ---------------------------------------------------UUGUGACAGAUUGAUAACUGu------------------------- 2 -1,-3 ---------------------------------------------------UUGUGACAGAUUGAUAACUGA------------------------- 83 -1,-2 ---------------------------------------------------UUGUGACAGAUUGAUAACUGAA------------------------ 43 -1,-1 ---------------------------------------------------UUGUGACAGAUUGAUAACUGAAu----------------------- 5 -1,-1 ---------------------------------------------------UUGUGACAGAUUGAUAACUGAAA----------------------- 16 -1,0 ----------------------------------------------------UGUGACAGAUUGAUAACUG-------------------------- 8 0,-3 ----------------------------------------------------UGUGACAGAUUGAUAACUGA------------------------- 208 0,-2 ----------------------------------------------------UGUGACAGAUUGAUAACUGAA------------------------ 258 0,-1 ----------------------------------------------------UGUGACAGAUUGAUAACUGAAc----------------------- 3 0,-1 ----------------------------------------------------UGUGACAGAUUGAUAACUGAAu----------------------- 34 0,-1 ----------------------------------------------------UGUGACAGAUUGAUAACUGAAA----------------------- 403 0,0 ----------------------------------------------------UGUGACAGAUUGAUAACUGAAAa---------------------- 24 0,0 ----------------------------------------------------UGUGACAGAUUGAUAACUGAAAu---------------------- 25 0,0 ----------------------------------------------------UGUGACAGAUUGAUAACUGAAAG---------------------- 10 0,1 -----------------------------------------------------GUGACAGAUUGAUAACUGA------------------------- 5 1,-2 -----------------------------------------------------GUGACAGAUUGAUAACUGAA------------------------ 4 1,-1 -----------------------------------------------------GUGACAGAUUGAUAACUGAAA----------------------- 14 1,0 -----------------------------------------------------GUGACAGAUUGAUAACUGAAAu---------------------- 4 1,0 >hsa-mir-543 3pM:47-68 Normal uacuuaaugagaaguugcccguguuuuuuucgcuuuauuugugacgAAACAUUCGCGGUGCACUUCUUuuucaguauc ----------GAAGUUGCCCGUGUUUUUUUCG---------------------------------------------- 3 -----------AAGUUGCCCGUGUUUUUUUCG---------------------------------------------- 2 ----------------------------------------------AAACAUUCGCGGUGCACUUCU----------- 3 0,-1 ----------------------------------------------AAACAUUCGCGGUGCACUUCUU---------- 34 0,0 ----------------------------------------------AAACAUUCGCGGUGCACUUCUUa--------- 4 0,0 ----------------------------------------------AAACAUUCGCGGUGCACUUCUUU--------- 15 0,1 ----------------------------------------------AAACAUUCGCGGUGCACUUCUUUU-------- 2 0,2 -----------------------------------------------AACAUUCGCGGUGCACUUCUU---------- 4 1,0 >hsa-mir-545 mi:25-46;MA:63-84 Normal cccagccuggcacauuaguaggccUCAGUAAAUGUUUAUUAGAUGAauaaaugaaugacucaUCAGCAAACAUUUAUUGUGUGCcugcuaaagugagcuccacagg --------------------------------------------------------------UCAGCAAACAUUUAUUGUGUG----------------------- 4 0,-1 --------------------------------------------------------------UCAGCAAACAUUUAUUGUGUGC---------------------- 6 0,0 >hsa-mir-548aa-1 3pM:55-79 Normal cuuuauuagucuggugcaaaagaaacugugguuuuugccauuacuuuuacaggcAAAAACCACAAUUACUUUUGCACCAaccuaauauaacuuguuu -----------------------------------------------------CAAAAACCACAAUUACUUUUGC---------------------- 2 -1,-4 >hsa-mir-548aa-2 3pM:55-79 Normal uuuuauuagguuggugcaaaagaaacugugguuuuugccauuacuuucaauggcAAAAACCACAAUUACUUUUGCACCAaccuaaaucuucccucuc -----------------------------------------------------CAAAAACCACAAUUACUUUUGC---------------------- 2 -1,-4 >hsa-mir-548am 3pM:46-67 Normal aguuggugcaaaaguaauugcgguuuuugccgucgaaaauaauggCAAAAACUGCAGUUACUUUUGUaccaaug ---------AAAAGUAAUUGCGGUUUUUGa-------------------------------------------- 2 ---------AAAAGUAAUUGCGGUUUUUGCC------------------------------------------- 8 >hsa-mir-548b 5p:25-46;3p:61-82 Normal cagacuauauauuuagguuggcgcAAAAGUAAUUGUGGUUUUGGCCuuuauuuucaauggCAAGAACCUCAGUUGCUUUUGUgccaaccuaauacuu ------------------------AAAAGUAAUUGUGGUUUUGGCC--------------------------------------------------- 2 0,0 ------------------------------------------------------------CAAGAACCUCAGUUGCUUUU----------------- 2 0,-2 ------------------------------------------------------------CAAGAACCUCAGUUGCUUUUG---------------- 2 0,-1 ------------------------------------------------------------CAAGAACCUCAGUUGCUUUUGU--------------- 16 0,0 -------------------------------------------------------------AAGAACCUCAGUUGCUUUUGU--------------- 2 1,0 >hsa-mir-548c 5p:25-46;3p:61-82 Normal cauuggcaucuauuagguuggugcAAAAGUAAUUGCGGUUUUUGCCauuacuuucaguagCAAAAAUCUCAAUUACUUUUGCaccaacuuaauacuu ------------------------AAAAGUAAUUGCGGUUUUUGa---------------------------------------------------- 2 0,-2 ------------------------AAAAGUAAUUGCGGUUUUUGCC--------------------------------------------------- 8 0,0 >hsa-mir-548e 3pM:53-74 Normal uuauuagguugguacaaaagcaaucgcgguuuuugcuauuacuuuuaaaggcAAAAACUGAGACUACUUUUGCAccaaccugauagaa ---------------AAAAGCAAUCGCGGUUUUUGCU--------------------------------------------------- 4 ----------------------------------------------------AAAAACUGAGACUACUUUUG---------------- 2 0,-2 ----------------------------------------------------AAAAACUGAGACUACUUUUGC--------------- 2 0,-1 ----------------------------------------------------AAAAACUGAGACUACUUUUGCA-------------- 6 0,0 >hsa-mir-548k 5pM:32-53 Normal cuuuucucaaguauugcuguuagguuggugcAAAAGUACUUGCGGAUUUUGCUuuacuuuuaauggcaaaaaccgcaauuauuuuugcuucaaccuaauaugaugcaaaauuggcu -------------------------------AAAAGUACUUGCGGAUUUUGC---------------------------------------------------------------- 2 0,-1 -------------------------------AAAAGUACUUGCGGAUUUUGCU--------------------------------------------------------------- 2 0,0 >hsa-mir-548o 3pM:87-108 Normal uggugaaaauguguugauuguaaugguuccuauucugaucaauaaacaugguuugagccuaguuacaaugaucuaaaauucacgguCCAAAACUGCAGUUACUUUUGCaccaac --------------------------------------------------------------------------------------CCAAAACUGCAGUUACUUUU-------- 2 0,-2 >hsa-mir-548o-2 3pM:45-66 Normal uggugcaaaaguaauugcgguuuuugccauuaaaaguaaugcggCCAAAACUGCAGUUACUUUUGCaccc ------AAAAGUAAUUGCGGUUUUUGa------------------------------------------- 2 ------AAAAGUAAUUGCGGUUUUUGCC------------------------------------------ 8 --------------------------------------------CCAAAACUGCAGUUACUUUU------ 2 0,-2 >hsa-mir-548t 5pM:10-30 Normal aggguggugCAAAAGUGAUCGUGGUUUUUGcaauuuuuuaaugacaaaaaccacaauuacuuuugcaccaaccu --------------------------------------------CAAAAACCACAAUUACUUUUGC-------- 2 >hsa-mir-550a-1 MA:22-44;mi:61-82 Normal ugaugcuuugcuggcuggugcAGUGCCUGAGGGAGUAAGAGCCCuguuguuguaagauagUGUCUUACUCCCUCAGGCACAUcuccaacaagucucu ---------------------AGUGCCUGAGGGAGUAAGA--------------------------------------------------------- 2 0,-4 ---------------------AGUGCCUGAGGGAGUAAGAGa------------------------------------------------------- 2 0,-3 ---------------------AGUGCCUGAGGGAGUAAGAGC------------------------------------------------------- 4 0,-2 ------------------------------------------------------------UGUCUUACUCCCUCAGGCACA---------------- 4 0,-1 ------------------------------------------------------------UGUCUUACUCCCUCAGGCACAU--------------- 3 0,0 >hsa-mir-550a-2 MA:22-44;mi:61-82 Normal ugaugcuuugcuggcuggugcAGUGCCUGAGGGAGUAAGAGCCCuguuguugucagauagUGUCUUACUCCCUCAGGCACAUcuccagcgagucucu ---------------------AGUGCCUGAGGGAGUAAGA--------------------------------------------------------- 2 0,-4 ---------------------AGUGCCUGAGGGAGUAAGAGa------------------------------------------------------- 2 0,-3 ---------------------AGUGCCUGAGGGAGUAAGAGC------------------------------------------------------- 4 0,-2 ------------------------------------------------------------UGUCUUACUCCCUCAGGCACA---------------- 4 0,-1 ------------------------------------------------------------UGUCUUACUCCCUCAGGCACAU--------------- 3 0,0 >hsa-mir-550a-3 3pM:60-81 Normal gaugcuuugcuggcuggugcagugccugagggaguaagaguccuguuguuguaagauagUGUCUUACUCCCUCAGGCACAUcuccaacaagucuc --------------------AGUGCCUGAGGGAGUAAGA-------------------------------------------------------- 2 --------------------AGUGCCUGAGGGAGUAAGAGa------------------------------------------------------ 2 -----------------------------------------------------------UGUCUUACUCCCUCAGGCACA--------------- 4 0,-1 -----------------------------------------------------------UGUCUUACUCCCUCAGGCACAU-------------- 3 0,0 >hsa-mir-551a 3pM:61-81 Normal ggggacugccgggugacccuggaaauccagaguggguggggccagucugaccguuucuagGCGACCCACUCUUGGUUUCCAggguugcccuggaaa ------------------------------------------------------------GCGACCCACUCUUGGUUUCCA--------------- 3 0,0 >hsa-mir-551b mi:22-43;MA:61-81 Normal agaugugcucuccuggcccauGAAAUCAAGCGUGGGUGAGACCuggugcagaacgggaagGCGACCCAUACUUGGUUUCAGaggcugugagaauaa ---------------------GAAAUCAAGCGUGGGUGAGACCU---------------------------------------------------- 2 0,1 ------------------------------------------------------------GCGACCCAUACUUGGUUUCA---------------- 10 0,-1 ------------------------------------------------------------GCGACCCAUACUUGGUUUCAG--------------- 12 0,0 ------------------------------------------------------------GCGACCCAUACUUGGUUUCAGu-------------- 67 0,0 ------------------------------------------------------------GCGACCCAUACUUGGUUUCAGA-------------- 6 0,1 >hsa-mir-556 5p:16-37;3p:55-76 Normal gauaguaauaagaaaGAUGAGCUCAUUGUAAUAUGAGcuucauuuauacauuucAUAUUACCAUUAGCUCAUCUUUuuuauuacuaccuucaaca ---------------GAUGAGCUCAUUGUAAUAUG------------------------------------------------------------ 2 0,-2 ---------------GAUGAGCUCAUUGUAAUAUGA----------------------------------------------------------- 12 0,-1 ---------------GAUGAGCUCAUUGUAAUAUGAa---------------------------------------------------------- 2 0,-1 >hsa-mir-570 3pM:60-81 Normal cuagauaaguuauuaggugggugcaaagguaauugcaguuuuucccauuauuuuaauugCGAAAACAGCAAUUACCUUUGCaccaaccugauggagu -----------------------------------------------------------CGAAAACAGCAAUUACCUUUGC---------------- 2 0,0 >hsa-mir-574 5p:25-47;3p:61-82 Normal gggaccugcgugggugcgggcgugUGAGUGUGUGUGUGUGAGUGUGUgucgcuccgggucCACGCUCAUGCACACACCCACAcgcccacacucagg ------------------------UGAGUGUGUGUGUGUGAG------------------------------------------------------ 4 0,-5 ------------------------UGAGUGUGUGUGUGUGAGa----------------------------------------------------- 6 0,-5 ------------------------UGAGUGUGUGUGUGUGAGU----------------------------------------------------- 32 0,-4 ------------------------UGAGUGUGUGUGUGUGAGUaa--------------------------------------------------- 2 0,-4 ------------------------UGAGUGUGUGUGUGUGAGUG---------------------------------------------------- 2 0,-3 ------------------------UGAGUGUGUGUGUGUGAGUGa--------------------------------------------------- 31 0,-3 ------------------------UGAGUGUGUGUGUGUGAGUGaa-------------------------------------------------- 2 0,-3 ------------------------UGAGUGUGUGUGUGUGAGUGU--------------------------------------------------- 283 0,-2 ------------------------UGAGUGUGUGUGUGUGAGUGUaa------------------------------------------------- 12 0,-2 ------------------------UGAGUGUGUGUGUGUGAGUGUuu------------------------------------------------- 6 0,-2 ------------------------UGAGUGUGUGUGUGUGAGUGUG-------------------------------------------------- 48 0,-1 ------------------------UGAGUGUGUGUGUGUGAGUGUGa------------------------------------------------- 125 0,-1 ------------------------UGAGUGUGUGUGUGUGAGUGUGaa------------------------------------------------ 3 0,-1 ------------------------UGAGUGUGUGUGUGUGAGUGUGau------------------------------------------------ 2 0,-1 ------------------------UGAGUGUGUGUGUGUGAGUGUGU------------------------------------------------- 455 0,0 ------------------------UGAGUGUGUGUGUGUGAGUGUGUa------------------------------------------------ 2 0,0 ------------------------UGAGUGUGUGUGUGUGAGUGUGUu------------------------------------------------ 12 0,0 ------------------------UGAGUGUGUGUGUGUGAGUGUGUuu----------------------------------------------- 8 0,0 ------------------------UGAGUGUGUGUGUGUGAGUGUGUG------------------------------------------------ 88 0,1 ------------------------UGAGUGUGUGUGUGUGAGUGUGUGa----------------------------------------------- 49 0,1 ------------------------UGAGUGUGUGUGUGUGAGUGUGUGU----------------------------------------------- 111 0,2 -------------------------GAGUGUGUGUGUGUGAGUG---------------------------------------------------- 2 1,-3 -------------------------GAGUGUGUGUGUGUGAGUGaa-------------------------------------------------- 2 1,-3 -------------------------GAGUGUGUGUGUGUGAGUGU--------------------------------------------------- 9 1,-2 -------------------------GAGUGUGUGUGUGUGAGUGUG-------------------------------------------------- 4 1,-1 -------------------------GAGUGUGUGUGUGUGAGUGUGa------------------------------------------------- 2 1,-1 -------------------------GAGUGUGUGUGUGUGAGUGUGU------------------------------------------------- 11 1,0 -------------------------GAGUGUGUGUGUGUGAGUGUGUGU----------------------------------------------- 4 1,2 ------------------------------------------------------------CACGCUCAUGCACACACC------------------ 2 0,-4 ------------------------------------------------------------CACGCUCAUGCACACACCC----------------- 18 0,-3 ------------------------------------------------------------CACGCUCAUGCACACACCCc---------------- 2 0,-3 ------------------------------------------------------------CACGCUCAUGCACACACCCA---------------- 109 0,-2 ------------------------------------------------------------CACGCUCAUGCACACACCCAa--------------- 8 0,-2 ------------------------------------------------------------CACGCUCAUGCACACACCCAu--------------- 5 0,-2 ------------------------------------------------------------CACGCUCAUGCACACACCCAC--------------- 250 0,-1 ------------------------------------------------------------CACGCUCAUGCACACACCCACc-------------- 6 0,-1 ------------------------------------------------------------CACGCUCAUGCACACACCCACg-------------- 5 0,-1 ------------------------------------------------------------CACGCUCAUGCACACACCCACu-------------- 35 0,-1 ------------------------------------------------------------CACGCUCAUGCACACACCCACA-------------- 1229 0,0 ------------------------------------------------------------CACGCUCAUGCACACACCCACAa------------- 26 0,0 ------------------------------------------------------------CACGCUCAUGCACACACCCACAau------------ 2 0,0 ------------------------------------------------------------CACGCUCAUGCACACACCCACAu------------- 21 0,0 -------------------------------------------------------------ACGCUCAUGCACACACCC----------------- 2 1,-3 -------------------------------------------------------------ACGCUCAUGCACACACCCA---------------- 2 1,-2 -------------------------------------------------------------ACGCUCAUGCACACACCCAC--------------- 8 1,-1 -------------------------------------------------------------ACGCUCAUGCACACACCCACA-------------- 57 1,0 -------------------------------------------------------------ACGCUCAUGCACACACCCACAu------------- 2 1,0 >hsa-mir-576 5p:16-37;3p:55-76 Normal uacaauccaacgaggAUUCUAAUUUCUCCACGUCUUUgguaauaagguuuggcaAAGAUGUGGAAAAAUUGGAAUCcucauucgauugguuauaacca ---------------AUUCUAAUUUCUCCACGUCU--------------------------------------------------------------- 4 0,-2 ---------------AUUCUAAUUUCUCCACGUCUU-------------------------------------------------------------- 5 0,-1 ---------------AUUCUAAUUUCUCCACGUCUUU------------------------------------------------------------- 9 0,0 ---------------AUUCUAAUUUCUCCACGUCUUUG------------------------------------------------------------ 2 0,1 ------------------------------------------------------AAGAUGUGGAAAAAUUGGA------------------------- 6 0,-3 ------------------------------------------------------AAGAUGUGGAAAAAUUGGAA------------------------ 10 0,-2 ------------------------------------------------------AAGAUGUGGAAAAAUUGGAAa----------------------- 11 0,-2 ------------------------------------------------------AAGAUGUGGAAAAAUUGGAAU----------------------- 66 0,-1 ------------------------------------------------------AAGAUGUGGAAAAAUUGGAAUC---------------------- 8 0,0 ------------------------------------------------------AAGAUGUGGAAAAAUUGGAAUCC--------------------- 20 0,1 -------------------------------------------------------AGAUGUGGAAAAAUUGGAA------------------------ 2 1,-2 >hsa-mir-582 5p:16-38;3p:53-74 Normal aucugugcucuuugaUUACAGUUGUUCAACCAGUUACUaaucuaacuaauugUAACUGGUUGAACAACUGAACCcaaagggugcaaaguagaaacauu ---------------UUACAGUUGUUCAACCAGUU--------------------------------------------------------------- 3 0,-3 ---------------UUACAGUUGUUCAACCAGUUAC------------------------------------------------------------- 4 0,-1 ---------------UUACAGUUGUUCAACCAGUUACU------------------------------------------------------------ 9 0,0 ----------------------------------------------------UAACUGGUUGAACAACUGA--------------------------- 2 0,-3 ----------------------------------------------------UAACUGGUUGAACAACUGAACC------------------------ 2 0,0 >hsa-mir-584 5pM:16-37 Normal uagggugaccagccaUUAUGGUUUGCCUGGGACUGAGgaauuugcugggauaugucaguuccaggccaaccaggcugguuggucucccugaagcaac ---------------UUAUGGUUUGCCUGGGACUGA------------------------------------------------------------- 8 0,-1 >hsa-mir-589 MA:24-45;mi:61-84 Normal uccagccugugcccagcagccccUGAGAACCACGUCUGCUCUGAGcuggguacugccuguUCAGAACAAAUGCCGGUUCCCAGAcgcugccagcuggcc -----------------------UGAGAACCACGUCUGCUCUGA------------------------------------------------------- 35 0,-1 -----------------------UGAGAACCACGUCUGCUCUGAG------------------------------------------------------ 2 0,0 -----------------------UGAGAACCACGUCUGCUCUGAGa----------------------------------------------------- 2 0,0 -----------------------UGAGAACCACGUCUGCUCUGAGC----------------------------------------------------- 6 0,1 >hsa-mir-590 5p:16-37;3p:56-76 Normal uagccagucagaaauGAGCUUAUUCAUAAAAGUGCAGuauggugaagucaaucugUAAUUUUAUGUAUAAGCUAGUcucugauugaaacaugcagca ---------------GAGCUUAUUCAUAAAAGUGCA------------------------------------------------------------- 7 0,-1 ---------------GAGCUUAUUCAUAAAAGUGCAG------------------------------------------------------------ 63 0,0 ------------------------------------------------------GUAAUUUUAUGUAUAAGCUAGU--------------------- 14 -1,0 -------------------------------------------------------UAAUUUUAUGUAUAAGCUAGU--------------------- 11 0,0 >hsa-mir-597 5pM:16-37 Normal uacuuacucuacgugUGUGUCACUCGAUGACCACUGUgaagacaguaaaauguacagugguucucuuguggcucaagcguaauguagaguacugguc ---------------UGUGUCACUCGAUGACCACUGU------------------------------------------------------------ 4 0,0 >hsa-mir-598 3pM:61-82 Normal gcuugaugaugcugcugaugcuggcggugaucccgauggugugagcuggaaauggggugcUACGUCAUCGUUGUCAUCGUCAucaucaucauccgag -----------------------GCGGUGAUCCCGAUGGUGUGAGC--------------------------------------------------- 2 ------------------------------------------------------------UACGUCAUCGUUGUCAUCGU----------------- 2 0,-2 ------------------------------------------------------------UACGUCAUCGUUGUCAUCGUC---------------- 8 0,-1 ------------------------------------------------------------UACGUCAUCGUUGUCAUCGUCA--------------- 36 0,0 ------------------------------------------------------------UACGUCAUCGUUGUCAUCGUCAU-------------- 2 0,1 >hsa-mir-615 5p:18-39;3p:61-82 Normal cucgggaggggcgggagGGGGGUCCCCGGUGCUCGGAUCucgagggugcuuauuguucggUCCGAGCCUGGGUCUCCCUCUUccccccaacccccc -----------------GGGGGUCCCCGGUGCUCGGAUCU-------------------------------------------------------- 2 0,1 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUCU--------------- 27 0,-1 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUCUU-------------- 27 0,0 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUCUUa------------- 2 0,0 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUCUUu------------- 9 0,0 >hsa-mir-618 5pM:16-38 Normal cucuuguucacagccAAACUCUACUUGUCCUUCUGAGUguaauuacguacaugcaguagcucaggagacaagcagguuuacccuguggaugagucuga ---------------AAACUCUACUUGUCCUUCUGAGa------------------------------------------------------------ 2 0,-1 ---------------AAACUCUACUUGUCCUUCUGAGU------------------------------------------------------------ 9 0,0 >hsa-mir-625 MA:15-35;mi:52-73 Normal aggguagagggaugAGGGGGAAAGUUCUAUAGUCCuguaauuagaucucagGACUAUAGAACUUUCCCCCUCAucccucugcccu --------------AGGGGGAAAGUUCUAUAGUC--------------------------------------------------- 4 0,-1 --------------AGGGGGAAAGUUCUAUAGUCC-------------------------------------------------- 13 0,0 --------------AGGGGGAAAGUUCUAUAGUCCU------------------------------------------------- 18 0,1 ---------------------------------------------------GACUAUAGAACUUUCCCCCUCA------------ 10 0,0 >hsa-mir-627 5pM:16-37 Normal uacuuauuacugguaGUGAGUCUCUAAGAAAAGAGGAggugguuguuuuccuccucuuuucuuugagacucacuaccaauaauaagaaauacuacua ---------------GUGAGUCUCUAAGAAAAGAGG------------------------------------------------------------- 3 0,-1 ---------------GUGAGUCUCUAAGAAAAGAGGu------------------------------------------------------------ 2 0,-1 ---------------GUGAGUCUCUAAGAAAAGAGGA------------------------------------------------------------ 30 0,0 ---------------GUGAGUCUCUAAGAAAAGAGGAa----------------------------------------------------------- 5 0,0 ----------------UGAGUCUCUAAGAAAAGAGGA------------------------------------------------------------ 9 1,0 ----------------UGAGUCUCUAAGAAAAGAGGAa----------------------------------------------------------- 2 1,0 ----------------UGAGUCUCUAAGAAAAGAGGAG----------------------------------------------------------- 28 1,1 ----------------UGAGUCUCUAAGAAAAGAGGAGa---------------------------------------------------------- 2 1,1 ----------------UGAGUCUCUAAGAAAAGAGGAGu---------------------------------------------------------- 4 1,1 ------------------------------------------------------UCUUUUCUUUGAGACUCACU----------------------- 2 >hsa-mir-628 5p:23-44;3p:61-81 Normal auagcuguugugucacuuccucAUGCUGACAUAUUUACUAGAGGguaaaauuaauaaccuUCUAGUAAGAGUGGCAGUCGAagggaagggcucau ----------------------AUGCUGACAUAUUUACUAGA----------------------------------------------------- 2 0,-2 ----------------------AUGCUGACAUAUUUACUAGAGG--------------------------------------------------- 5 0,0 >hsa-mir-629 MA:22-42;mi:61-82 Normal ucccuuucccaggggaggggcUGGGUUUACGUUGGGAGAACUuuuacggugaaccaggagGUUCUCCCAACGUAAGCCCAGCcccuccccucugccu ---------------------UGGGUUUACGUUGGGAGAAa-------------------------------------------------------- 2 0,-2 ---------------------UGGGUUUACGUUGGGAGAAC-------------------------------------------------------- 14 0,-1 ---------------------UGGGUUUACGUUGGGAGAACU------------------------------------------------------- 68 0,0 ---------------------UGGGUUUACGUUGGGAGAACUU------------------------------------------------------ 72 0,1 ---------------------UGGGUUUACGUUGGGAGAACUUa----------------------------------------------------- 2 0,1 ---------------------UGGGUUUACGUUGGGAGAACUUU----------------------------------------------------- 11 0,2 ----------------------GGGUUUACGUUGGGAGAACU------------------------------------------------------- 2 1,0 ----------------------GGGUUUACGUUGGGAGAACUU------------------------------------------------------ 2 1,1 ----------------------GGGUUUACGUUGGGAGAACUUU----------------------------------------------------- 4 1,2 ------------------------------------------------------------GUUCUCCCAACGUAAGCCCAGC--------------- 2 0,0 >hsa-mir-642a 5pM:16-37 Normal aucugaguugggaggGUCCCUCUCCAAAUGUGUCUUGgggugggggaucaagacacauuuggagagggaaccucccaacucggccucugccaucauu ---------------GUCCCUCUCCAAAUGUGUCUUGa----------------------------------------------------------- 2 0,0 --------------------------------------------------AGACACAUUUGGAGAGGGAAC-------------------------- 2 >hsa-mir-651 5pM:16-37 Normal aaucuaucacugcuuUUUAGGAUAAGCUUGACUUUUGuucaaauaaaaaugcaaaaggaaaguguauccuaaaaggcaaugacaguuuaauguguuu ---------------UUUAGGAUAAGCUUGACUUUU------------------------------------------------------------- 6 0,-1 ---------------UUUAGGAUAAGCUUGACUUUUG------------------------------------------------------------ 5 0,0 -----------------------------------------------------AAAGGAAAGUGUAUCCUAAAAG---------------------- 2 >hsa-mir-652 3pM:61-81 Normal acgaauggcuaugcacugcacaacccuaggagagggugccauucacauagacuauaauugAAUGGCGCCACUAGGGUUGUGcagugcacaaccuacac -------------------ACAACCCUAGGAGAGGGUGCC---------------------------------------------------------- 2 -------------------ACAACCCUAGGAGAGGGUGCCA--------------------------------------------------------- 7 -------------------ACAACCCUAGGAGAGGGUGCCAU-------------------------------------------------------- 4 -------------------ACAACCCUAGGAGAGGGUGCCAUU------------------------------------------------------- 3 -------------------ACAACCCUAGGAGAGGGUGCCAUUC------------------------------------------------------ 2 --------------------CAACCCUAGGAGAGGGUGCCA--------------------------------------------------------- 2 ------------------------------------------------------------AAUGGCGCCACUAGGGUU-------------------- 2 0,-3 ------------------------------------------------------------AAUGGCGCCACUAGGGUUG------------------- 9 0,-2 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGU------------------ 100 0,-1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUaa---------------- 2 0,-1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUau---------------- 4 0,-1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUu----------------- 3 0,-1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUuu---------------- 4 0,-1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUG----------------- 185 0,0 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGa---------------- 296 0,0 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGaa--------------- 23 0,0 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGau--------------- 2 0,0 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGu---------------- 820 0,0 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGuu--------------- 31 0,0 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGC---------------- 214 0,1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGCu--------------- 13 0,1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGCuu-------------- 4 0,1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGCA--------------- 17 0,2 -------------------------------------------------------------AUGGCGCCACUAGGGUUGU------------------ 3 1,-1 -------------------------------------------------------------AUGGCGCCACUAGGGUUGUuu---------------- 2 1,-1 -------------------------------------------------------------AUGGCGCCACUAGGGUUGUGa---------------- 5 1,0 -------------------------------------------------------------AUGGCGCCACUAGGGUUGUGu---------------- 14 1,0 -------------------------------------------------------------AUGGCGCCACUAGGGUUGUGuu--------------- 2 1,0 -------------------------------------------------------------AUGGCGCCACUAGGGUUGUGC---------------- 3 1,1 >hsa-mir-653 5pM:13-33 Normal uucauuccuucaGUGUUGAAACAAUCUCUACUGaaccagcuucaaacaaguucacuggaguuuguuucaauauugcaagaaugauaagauggaagc --------------------------------------------------UUCACUGGAGUUUGUUUCA--------------------------- 5 --------------------------------------------------UUCACUGGAGUUUGUUUCAA-------------------------- 3 --------------------------------------------------UUCACUGGAGUUUGUUUCAAU------------------------- 12 --------------------------------------------------UUCACUGGAGUUUGUUUCAAUA------------------------ 2 >hsa-mir-654 5p:16-37;3p:51-72 Normal ggguaaguggaaagaUGGUGGGCCGCAGAACAUGUGCugaguucgugccaUAUGUCUGCUGACCAUCACCUUuagaagccc --------------AUGGUGGGCCGCAGAACAUGUG--------------------------------------------- 4 -1,-1 --------------AUGGUGGGCCGCAGAACAUGUGu-------------------------------------------- 3 -1,-1 ---------------UGGUGGGCCGCAGAACAUGUGa-------------------------------------------- 2 0,-1 ---------------UGGUGGGCCGCAGAACAUGUGC-------------------------------------------- 16 0,0 --------------------------------------------------UAUGUCUGCUGACCAUCACa----------- 2 0,-3 --------------------------------------------------UAUGUCUGCUGACCAUCACC----------- 18 0,-2 --------------------------------------------------UAUGUCUGCUGACCAUCACCa---------- 6 0,-2 --------------------------------------------------UAUGUCUGCUGACCAUCACCau--------- 2 0,-2 --------------------------------------------------UAUGUCUGCUGACCAUCACCU---------- 17 0,-1 --------------------------------------------------UAUGUCUGCUGACCAUCACCUU--------- 5 0,0 >hsa-mir-655 3pM:61-82 Normal aacuaugcaaggauauuugaggagagguuauccguguuauguucgcuucauucaucaugaAUAAUACAUGGUUAACCUCUUUuugaauaucagacuc ------------------------------------------------------------AUAAUACAUGGUUAACCUCUU---------------- 4 0,-1 ------------------------------------------------------------AUAAUACAUGGUUAACCUCUUU--------------- 56 0,0 >hsa-mir-656 3pM:43-63 Normal cugaaauagguugccugugagguguucacuuucuauaugaugAAUAUUAUACAGUCAACCUCUuuccgauaucgaauc -------AGGUUGCCUGUGAGGUGUUC--------------------------------------------------- 6 ------------------------------------------AAUAUUAUACAGUCAACCUCU--------------- 16 0,0 >hsa-mir-659 3pM:61-82 Normal uaccgacccucgauuugguucaggaccuucccugaaccaaggaagagucacagucucuucCUUGGUUCAGGGAGGGUCCCCAacaauguccucaugg ---------------------AGGACCUUCCCUGAACCAAGGA------------------------------------------------------ 2 >hsa-mir-660 5pM:16-37 Normal cugcuccuucucccaUACCCAUUGCAUAUCGGAGUUGugaauucucaaaacaccuccugugugcauggauuacaggagggugagccuugucaucgug ---------------UACCCAUUGCAUAUCGGAGUU------------------------------------------------------------- 2 0,-1 ---------------UACCCAUUGCAUAUCGGAGUUG------------------------------------------------------------ 66 0,0 ---------------UACCCAUUGCAUAUCGGAGUUGa----------------------------------------------------------- 18 0,0 ---------------UACCCAUUGCAUAUCGGAGUUGU----------------------------------------------------------- 171 0,1 ----------------ACCCAUUGCAUAUCGGAGUUG------------------------------------------------------------ 2 1,0 ----------------ACCCAUUGCAUAUCGGAGUUGU----------------------------------------------------------- 4 1,1 ---------------------------------------------------ACCUCCUGUGUGCAUGGAUU-------------------------- 3 ---------------------------------------------------ACCUCCUGUGUGCAUGGAUUA------------------------- 2 ---------------------------------------------------ACCUCCUGUGUGCAUGGAUUAC------------------------ 2 >hsa-mir-664 mi:11-34;MA:49-71 Normal gaacauugaaACUGGCUAGGGAAAAUGAUUGGAUagaaacuauuauucUAUUCAUUUAUCCCCAGCCUACAaaaugaaaaaa ----------ACUGGCUAGGGAAAAUGAUU---------------------------------------------------- 2 0,-4 ----------ACUGGCUAGGGAAAAUGAUUG--------------------------------------------------- 3 0,-3 ----------ACUGGCUAGGGAAAAUGAUUGG-------------------------------------------------- 73 0,-2 ----------ACUGGCUAGGGAAAAUGAUUGGA------------------------------------------------- 47 0,-1 -----------CUGGCUAGGGAAAAUGAUUGG-------------------------------------------------- 4 1,-2 -----------CUGGCUAGGGAAAAUGAUUGGA------------------------------------------------- 25 1,-1 ------------UGGCUAGGGAAAAUGAUUGGA------------------------------------------------- 9 2,-1 ------------------------------------------------UAUUCAUUUAUCCCCAGCCUAC------------ 2 0,-1 ------------------------------------------------UAUUCAUUUAUCCCCAGCCUACA----------- 23 0,0 >hsa-mir-665 3pM:43-62 Normal ucuccucgaggggucucugccucuacccaggacucuuucaugACCAGGAGGCUGAGGCCCCUcacaggcggc ------------------------------------------ACCAGGAGGCUGAGGCCC------------ 2 0,-2 ------------------------------------------ACCAGGAGGCUGAGGCCCC----------- 9 0,-1 ------------------------------------------ACCAGGAGGCUGAGGCCCCU---------- 42 0,0 ------------------------------------------ACCAGGAGGCUGAGGCCCCUuu-------- 6 0,0 ------------------------------------------ACCAGGAGGCUGAGGCCCCUC--------- 14 0,1 ------------------------------------------ACCAGGAGGCUGAGGCCCCUCu-------- 16 0,1 ------------------------------------------ACCAGGAGGCUGAGGCCCCUCA-------- 51 0,2 ------------------------------------------ACCAGGAGGCUGAGGCCCCUCAa------- 2 0,2 ------------------------------------------ACCAGGAGGCUGAGGCCCCUCAaa------ 2 0,2 ------------------------------------------ACCAGGAGGCUGAGGCCCCUCAau------ 2 0,2 ------------------------------------------ACCAGGAGGCUGAGGCCCCUCAu------- 8 0,2 >hsa-mir-671 5p:29-51;3p:68-88 Normal gcaggugaacuggcaggccaggaagaggAGGAAGCCCUGGAGGGGCUGGAGgugauggauguuuuccUCCGGUUCUCAGGGCUCCACCucuuucgggccguagagccagggcuggugc ----------------------------AGGAAGCCCUGGAGGGGCUG---------------------------------------------------------------------- 8 0,-3 ----------------------------AGGAAGCCCUGGAGGGGCUGG--------------------------------------------------------------------- 9 0,-2 ----------------------------AGGAAGCCCUGGAGGGGCUGGA-------------------------------------------------------------------- 75 0,-1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAa------------------------------------------------------------------- 34 0,-1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAaa------------------------------------------------------------------ 10 0,-1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAau------------------------------------------------------------------ 41 0,-1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAu------------------------------------------------------------------- 11 0,-1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAuu------------------------------------------------------------------ 2 0,-1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAG------------------------------------------------------------------- 156 0,0 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGa------------------------------------------------------------------ 132 0,0 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGaa----------------------------------------------------------------- 8 0,0 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGau----------------------------------------------------------------- 4 0,0 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGu------------------------------------------------------------------ 71 0,0 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGG------------------------------------------------------------------ 265 0,1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGGa----------------------------------------------------------------- 12 0,1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGGU----------------------------------------------------------------- 42 0,2 -----------------------------GGAAGCCCUGGAGGGGCUGGAGa------------------------------------------------------------------ 4 1,0 -----------------------------GGAAGCCCUGGAGGGGCUGGAGG------------------------------------------------------------------ 2 1,1 -----------------------------GGAAGCCCUGGAGGGGCUGGAGGU----------------------------------------------------------------- 2 1,2 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCA-------------------------------- 2 0,-2 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCAC------------------------------- 4 0,-1 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCACu------------------------------ 2 0,-1 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCACC------------------------------ 5 0,0 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCACCa----------------------------- 2 0,0 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCACCU----------------------------- 5 0,1 >hsa-mir-675 MA:10-32;mi:45-64 Normal cccagggucUGGUGCGGAGAGGGCCCACAGUGgacuuggugacgCUGUAUGCCCUCACCGCUCAgccccuggg ---------UGGUGCGGAGAGGGCCCACAGUGu---------------------------------------- 2 0,0 --------------------------------------------CUGUAUGCCCUCACCGCUCAGC------- 6 0,2 >hsa-mir-7-1 MA:24-46;mi:66-87 Normal uuggauguuggccuaguucugugUGGAAGACUAGUGAUUUUGUUGUuuuuagauaacuaaaucgaCAACAAAUCACAGUCUGCCAUAuggcacaggccaugccucuacag -----------------------UGGAAGACUAGUGAUUUUGUU------------------------------------------------------------------ 6 0,-2 -----------------------UGGAAGACUAGUGAUUUUGUUG----------------------------------------------------------------- 12 0,-1 -----------------------UGGAAGACUAGUGAUUUUGUUGU---------------------------------------------------------------- 30 0,0 -----------------------UGGAAGACUAGUGAUUUUGUUGUU--------------------------------------------------------------- 89 0,1 -----------------------------------------------------------------CAACAAAUCACAGUCUGCCA------------------------- 2 0,-2 -----------------------------------------------------------------CAACAAAUCACAGUCUGCCAU------------------------ 2 0,-1 ------------------------------------------------------------------AACAAAUCACAGUCUGCCAUA----------------------- 3 1,0 >hsa-mir-7-2 MA:32-54;mi:72-93 Normal cuggauacagaguggaccggcuggccccaucUGGAAGACUAGUGAUUUUGUUGUugucuuacugcgcucaaCAACAAAUCCCAGUCUACCUAAuggugccagccaucgca -------------------------------UGGAAGACUAGUGAUUUUGUU---------------------------------------------------------- 6 0,-2 -------------------------------UGGAAGACUAGUGAUUUUGUUG--------------------------------------------------------- 12 0,-1 -------------------------------UGGAAGACUAGUGAUUUUGUUGU-------------------------------------------------------- 30 0,0 -------------------------------UGGAAGACUAGUGAUUUUGUUGUU------------------------------------------------------- 89 0,1 -------------------------------UGGAAGACUAGUGAUUUUGUUGUUG------------------------------------------------------ 5 0,2 >hsa-mir-7-3 5pM:31-53 Normal agauuagaguggcuguggucuagugcugugUGGAAGACUAGUGAUUUUGUUGUucugauguacuacgacaacaagucacagccggccucauagcgcagacucccuucgac ------------------------------UGGAAGACUAGUGAUUUUGUU----------------------------------------------------------- 6 0,-2 ------------------------------UGGAAGACUAGUGAUUUUGUUG---------------------------------------------------------- 12 0,-1 ------------------------------UGGAAGACUAGUGAUUUUGUUGU--------------------------------------------------------- 30 0,0 ------------------------------UGGAAGACUAGUGAUUUUGUUGUU-------------------------------------------------------- 89 0,1 >hsa-mir-708 MA:11-33;mi:57-78 Normal aacugcccucAAGGAGCUUACAAUCUAGCUGGGgguaaaugacuugcacaugaacaCAACUAGACUGUGAGCUUCUAGagggcaggga ----------AAGGAGCUUACAAUCUAGC----------------------------------------------------------- 4 0,-4 ----------AAGGAGCUUACAAUCUAGCU---------------------------------------------------------- 10 0,-3 ----------AAGGAGCUUACAAUCUAGCUG--------------------------------------------------------- 25 0,-2 ----------AAGGAGCUUACAAUCUAGCUGa-------------------------------------------------------- 17 0,-2 ----------AAGGAGCUUACAAUCUAGCUGu-------------------------------------------------------- 5 0,-2 ----------AAGGAGCUUACAAUCUAGCUGG-------------------------------------------------------- 491 0,-1 ----------AAGGAGCUUACAAUCUAGCUGGa------------------------------------------------------- 115 0,-1 ----------AAGGAGCUUACAAUCUAGCUGGaa------------------------------------------------------ 2 0,-1 ----------AAGGAGCUUACAAUCUAGCUGGu------------------------------------------------------- 23 0,-1 ----------AAGGAGCUUACAAUCUAGCUGGG------------------------------------------------------- 254 0,0 ----------AAGGAGCUUACAAUCUAGCUGGGa------------------------------------------------------ 33 0,0 ----------AAGGAGCUUACAAUCUAGCUGGGu------------------------------------------------------ 20 0,0 -----------AGGAGCUUACAAUCUAGCUGG-------------------------------------------------------- 10 1,-1 -----------AGGAGCUUACAAUCUAGCUGGa------------------------------------------------------- 2 1,-1 -----------AGGAGCUUACAAUCUAGCUGGG------------------------------------------------------- 4 1,0 --------------------------------------------------------CAACUAGACUGUGAGCUUCU------------ 8 0,-2 --------------------------------------------------------CAACUAGACUGUGAGCUUCUA----------- 4 0,-1 --------------------------------------------------------CAACUAGACUGUGAGCUUCUAG---------- 8 0,0 --------------------------------------------------------CAACUAGACUGUGAGCUUCUAGu--------- 2 0,0 --------------------------------------------------------CAACUAGACUGUGAGCUUCUAGA--------- 8 0,1 ---------------------------------------------------------AACUAGACUGUGAGCUUCUAG---------- 25 1,0 ---------------------------------------------------------AACUAGACUGUGAGCUUCUAGA--------- 71 1,1 ----------------------------------------------------------ACUAGACUGUGAGCUUCUAG---------- 4 2,0 ----------------------------------------------------------ACUAGACUGUGAGCUUCUAGA--------- 2 2,1 >hsa-mir-720 5pM:27-43 Normal ccggaucucacacggugguguuaauaUCUCGCUGGGGCCUCCAaaauguugugcccagggguguuagagaaaacaccacacuuugagaugaauuaagaguccuuuauuag -------------------------AUCUCGCUGGGGCCUCCA------------------------------------------------------------------- 49 -1,0 -------------------------AUCUCGCUGGGGCCUCCAAu----------------------------------------------------------------- 2 -1,1 --------------------------UCUCGCUGGGGCCUCCAAAA---------------------------------------------------------------- 2 0,3 >hsa-mir-744 MA:11-32;mi:68-89 Normal uugggcaaggUGCGGGGCUAGGGCUAACAGCAgucuuacugaagguuuccuggaaaccacgcacaugCUGUUGCCACUAACCUCAACCUuacucgguc ----------UGCGGGGCUAGGGCUAAC---------------------------------------------------------------------- 2 0,-4 ----------UGCGGGGCUAGGGCUAACA--------------------------------------------------------------------- 2 0,-3 ----------UGCGGGGCUAGGGCUAACAG-------------------------------------------------------------------- 24 0,-2 ----------UGCGGGGCUAGGGCUAACAGa------------------------------------------------------------------- 34 0,-2 ----------UGCGGGGCUAGGGCUAACAGaa------------------------------------------------------------------ 11 0,-2 ----------UGCGGGGCUAGGGCUAACAGau------------------------------------------------------------------ 2 0,-2 ----------UGCGGGGCUAGGGCUAACAGu------------------------------------------------------------------- 5 0,-2 ----------UGCGGGGCUAGGGCUAACAGC------------------------------------------------------------------- 138 0,-1 ----------UGCGGGGCUAGGGCUAACAGCu------------------------------------------------------------------ 7 0,-1 ----------UGCGGGGCUAGGGCUAACAGCA------------------------------------------------------------------ 278 0,0 ----------UGCGGGGCUAGGGCUAACAGCAa----------------------------------------------------------------- 59 0,0 ----------UGCGGGGCUAGGGCUAACAGCAaa---------------------------------------------------------------- 3 0,0 ----------UGCGGGGCUAGGGCUAACAGCAau---------------------------------------------------------------- 4 0,0 ----------UGCGGGGCUAGGGCUAACAGCAu----------------------------------------------------------------- 31 0,0 ----------UGCGGGGCUAGGGCUAACAGCAG----------------------------------------------------------------- 2 0,1 -----------GCGGGGCUAGGGCUAACAGa------------------------------------------------------------------- 2 1,-2 -----------GCGGGGCUAGGGCUAACAGC------------------------------------------------------------------- 7 1,-1 -----------GCGGGGCUAGGGCUAACAGCA------------------------------------------------------------------ 23 1,0 -----------GCGGGGCUAGGGCUAACAGCAa----------------------------------------------------------------- 4 1,0 -----------GCGGGGCUAGGGCUAACAGCAu----------------------------------------------------------------- 5 1,0 >hsa-mir-758 3pM:52-73 Normal gccuggauacaugagaugguugaccagagagcacacgcuuuauuugugccgUUUGUGACCUGGUCCACUAACCcucaguaucuaaugc ---------------AUGGUUGACCAGAGAGCACACG--------------------------------------------------- 6 ---------------AUGGUUGACCAGAGAGCACACGa-------------------------------------------------- 2 ---------------------------------------------------UUUGUGACCUGGUCCACUAAu---------------- 2 0,-2 ---------------------------------------------------UUUGUGACCUGGUCCACUAAC---------------- 11 0,-1 ---------------------------------------------------UUUGUGACCUGGUCCACUAACa--------------- 4 0,-1 ---------------------------------------------------UUUGUGACCUGGUCCACUAACu--------------- 14 0,-1 ---------------------------------------------------UUUGUGACCUGGUCCACUAACC--------------- 9 0,0 >hsa-mir-760 3pM:49-68 Normal ggcgcgucgccccccucaguccaccagagcccggauaccucagaaauuCGGCUCUGGGUCUGUGGGGAgcgaaaugcaac ------------------------------------------------CGGCUCUGGGUCUGUGGGGA------------ 89 0,0 ------------------------------------------------CGGCUCUGGGUCUGUGGGGAGu---------- 2 0,1 -------------------------------------------------GGCUCUGGGUCUGUGGGGA------------ 5 1,0 >hsa-mir-766 3pM:65-86 Normal gcauccucaggaccugggcuugggugguaggaggaauuggugcuggucuuucauuuuggauuugACUCCAGCCCCACAGCCUCAGCcaccccagccaauugucauaggagc ----------------------------AGGAGGAAUUGGUGCUGGUCUU------------------------------------------------------------- 2 ----------------------------------------------------------------ACUCCAGCCCCACAGCCUCA--------------------------- 2 0,-2 ----------------------------------------------------------------ACUCCAGCCCCACAGCCUCAG-------------------------- 4 0,-1 ----------------------------------------------------------------ACUCCAGCCCCACAGCCUCAGa------------------------- 6 0,-1 ----------------------------------------------------------------ACUCCAGCCCCACAGCCUCAGu------------------------- 2 0,-1 ----------------------------------------------------------------ACUCCAGCCCCACAGCCUCAGC------------------------- 8 0,0 >hsa-mir-769 5p:30-51;3p:69-91 Normal gccuuggugcugauuccugggcucugaccUGAGACCUCUGGGUUCUGAGCUgugauguugcucucgagCUGGGAUCUCCGGGGUCUUGGUUcagggccggggccucuggguuccaagc -----------------------------UGAGACCUCUGGGUUCUGAG--------------------------------------------------------------------- 51 0,-2 -----------------------------UGAGACCUCUGGGUUCUGAGa-------------------------------------------------------------------- 54 0,-2 -----------------------------UGAGACCUCUGGGUUCUGAGaa------------------------------------------------------------------- 3 0,-2 -----------------------------UGAGACCUCUGGGUUCUGAGu-------------------------------------------------------------------- 11 0,-2 -----------------------------UGAGACCUCUGGGUUCUGAGC-------------------------------------------------------------------- 120 0,-1 -----------------------------UGAGACCUCUGGGUUCUGAGCa------------------------------------------------------------------- 16 0,-1 -----------------------------UGAGACCUCUGGGUUCUGAGCaa------------------------------------------------------------------ 2 0,-1 -----------------------------UGAGACCUCUGGGUUCUGAGCau------------------------------------------------------------------ 2 0,-1 -----------------------------UGAGACCUCUGGGUUCUGAGCU------------------------------------------------------------------- 383 0,0 -----------------------------UGAGACCUCUGGGUUCUGAGCUa------------------------------------------------------------------ 4 0,0 -----------------------------UGAGACCUCUGGGUUCUGAGCUau----------------------------------------------------------------- 2 0,0 -----------------------------UGAGACCUCUGGGUUCUGAGCUu------------------------------------------------------------------ 45 0,0 -----------------------------UGAGACCUCUGGGUUCUGAGCUuu----------------------------------------------------------------- 17 0,0 ------------------------------GAGACCUCUGGGUUCUGAG--------------------------------------------------------------------- 2 1,-2 ------------------------------GAGACCUCUGGGUUCUGAGa-------------------------------------------------------------------- 2 1,-2 ------------------------------GAGACCUCUGGGUUCUGAGC-------------------------------------------------------------------- 5 1,-1 ------------------------------GAGACCUCUGGGUUCUGAGCU------------------------------------------------------------------- 25 1,0 --------------------------------------------------------------------CUGGGAUCUCCGGGGUCUUGGU---------------------------- 8 0,-1 ---------------------------------------------------------------------UGGGAUCUCCGGGGUCUUGGUU--------------------------- 5 1,0 ---------------------------------------------------------------------UGGGAUCUCCGGGGUCUUGGUUu-------------------------- 3 1,0 >hsa-mir-873 5pM:11-31 Normal gugugcauuuGCAGGAACUUGUGAGUCUCCUauugaaaaugaacaggagacugaugaguucccgggaacacccacaa ----------GCAGGAACUUGUGAGUCUCCU---------------------------------------------- 5 0,0 >hsa-mir-874 3pM:47-68 Normal uuagcccugcggccccacgcaccaggguaagagagacucucgcuucCUGCCCUGGCCCGAGGGACCGAcuggcugggc ---------CGGCCCCACGCACCAGGGUAu------------------------------------------------ 2 ---------CGGCCCCACGCACCAGGGUAA------------------------------------------------ 2 ---------CGGCCCCACGCACCAGGGUAAG----------------------------------------------- 15 ---------CGGCCCCACGCACCAGGGUAAGA---------------------------------------------- 17 -----------GCCCCACGCACCAGGGUAAGA---------------------------------------------- 4 ----------------------------------------------CUGCCCUGGCCCGAGGGA-------------- 9 0,-4 ----------------------------------------------CUGCCCUGGCCCGAGGGAa------------- 11 0,-4 ----------------------------------------------CUGCCCUGGCCCGAGGGAaa------------ 3 0,-4 ----------------------------------------------CUGCCCUGGCCCGAGGGAau------------ 2 0,-4 ----------------------------------------------CUGCCCUGGCCCGAGGGAC------------- 8 0,-3 ----------------------------------------------CUGCCCUGGCCCGAGGGACC------------ 10 0,-2 ----------------------------------------------CUGCCCUGGCCCGAGGGACCG----------- 6 0,-1 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGu---------- 5 0,-1 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGA---------- 355 0,0 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGAa--------- 27 0,0 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGAaa-------- 5 0,0 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGAau-------- 4 0,0 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGAg--------- 2 0,0 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGAu--------- 50 0,0 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGAuu-------- 11 0,0 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGAC--------- 256 0,1 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGACa-------- 34 0,1 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGACc-------- 2 0,1 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGACg-------- 4 0,1 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGACU-------- 106 0,2 -----------------------------------------------UGCCCUGGCCCGAGGGACCGA---------- 26 1,0 -----------------------------------------------UGCCCUGGCCCGAGGGACCGAC--------- 11 1,1 -----------------------------------------------UGCCCUGGCCCGAGGGACCGACa-------- 5 1,1 -----------------------------------------------UGCCCUGGCCCGAGGGACCGACU-------- 6 1,2 ------------------------------------------------GCCCUGGCCCGAGGGACCGA---------- 2 2,0 >hsa-mir-876 5p:11-32;3p:50-71 Normal ugaagugcugUGGAUUUCUUUGUGAAUCACCAuaucuaagcuaauguggUGGUGGUUUACAAAGUAAUUCAuagugcuuca ----------UGGAUUUCUUUGUGAAUCA---------------------------------------------------- 2 0,-3 ----------UGGAUUUCUUUGUGAAUCACC-------------------------------------------------- 5 0,-1 >hsa-mir-877 MA:1-20;mi:66-86 Normal GUAGAGGAGAUGGCGCAGGGgacacgggcaaagacuuggggguuccugggacccucagacgugugUCCUCUUCUCCCUCCUCCCAG GUAGAGGAGAUGGCGCAGGGGACA-------------------------------------------------------------- 2 0,4 -----------------------------------------------------------------UCCUCUUCUCCCUCCUCCCAGu 2 0,0 >hsa-mir-887 3pM:48-69 Normal gugcagauccuugggagcccuguuagacucuggauuuuacacuuggaGUGAACGGGCGCCAUCCCGAGGcuuugcacag -----------------------------------------------GUGAACGGGCGCCAUCCCG------------- 4 0,-3 -----------------------------------------------GUGAACGGGCGCCAUCCCGA------------ 17 0,-2 -----------------------------------------------GUGAACGGGCGCCAUCCCGAG----------- 27 0,-1 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGa---------- 24 0,-1 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGu---------- 2 0,-1 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGG---------- 61 0,0 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGa--------- 25 0,0 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGau-------- 2 0,0 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGu--------- 10 0,0 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGC--------- 36 0,1 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGCa-------- 9 0,1 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGCau------- 2 0,1 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGCc-------- 2 0,1 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGCU-------- 96 0,2 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGCUU------- 61 0,3 >hsa-mir-9-1 MA:16-38;mi:55-76 Normal cgggguugguuguuaUCUUUGGUUAUCUAGCUGUAUGAgugguguggagucuucAUAAAGCUAGAUAACCGAAAGUaaaaauaacccca ---------------UCUUUGGUUAUCUAGCUGUA------------------------------------------------------ 4 0,-3 ---------------UCUUUGGUUAUCUAGCUGUAa----------------------------------------------------- 2 0,-3 ---------------UCUUUGGUUAUCUAGCUGUAU----------------------------------------------------- 43 0,-2 ---------------UCUUUGGUUAUCUAGCUGUAUG---------------------------------------------------- 44 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGu--------------------------------------------------- 13 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGA--------------------------------------------------- 159 0,0 ----------------CUUUGGUUAUCUAGCUGUAU----------------------------------------------------- 2 1,-2 ----------------CUUUGGUUAUCUAGCUGUAUG---------------------------------------------------- 3 1,-1 ----------------CUUUGGUUAUCUAGCUGUAUGA--------------------------------------------------- 68 1,0 ----------------CUUUGGUUAUCUAGCUGUAUGAa-------------------------------------------------- 4 1,0 -----------------UUUGGUUAUCUAGCUGUAUGA--------------------------------------------------- 3 2,0 ------------------------------------------------------AUAAAGCUAGAUAACCGA----------------- 2 0,-4 ------------------------------------------------------AUAAAGCUAGAUAACCGAAA--------------- 2 0,-2 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGU------------- 104 0,0 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGUu------------ 3 0,0 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGUA------------ 2 0,1 -------------------------------------------------------UAAAGCUAGAUAACCGAAAGU------------- 5 1,0 -------------------------------------------------------UAAAGCUAGAUAACCGAAAGUA------------ 2 1,1 -------------------------------------------------------UAAAGCUAGAUAACCGAAAGUAA----------- 3 1,2 >hsa-mir-9-2 MA:16-38;mi:53-74 Normal ggaagcgaguuguuaUCUUUGGUUAUCUAGCUGUAUGAguguauuggucuucAUAAAGCUAGAUAACCGAAAGUaaaaacuccuuca ---------------UCUUUGGUUAUCUAGCUGUA---------------------------------------------------- 4 0,-3 ---------------UCUUUGGUUAUCUAGCUGUAa--------------------------------------------------- 2 0,-3 ---------------UCUUUGGUUAUCUAGCUGUAU--------------------------------------------------- 43 0,-2 ---------------UCUUUGGUUAUCUAGCUGUAUG-------------------------------------------------- 44 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGu------------------------------------------------- 13 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGA------------------------------------------------- 159 0,0 ----------------CUUUGGUUAUCUAGCUGUAU--------------------------------------------------- 2 1,-2 ----------------CUUUGGUUAUCUAGCUGUAUG-------------------------------------------------- 3 1,-1 ----------------CUUUGGUUAUCUAGCUGUAUGA------------------------------------------------- 68 1,0 ----------------CUUUGGUUAUCUAGCUGUAUGAa------------------------------------------------ 4 1,0 -----------------UUUGGUUAUCUAGCUGUAUGA------------------------------------------------- 3 2,0 ----------------------------------------------------AUAAAGCUAGAUAACCGA----------------- 2 0,-4 ----------------------------------------------------AUAAAGCUAGAUAACCGAAA--------------- 2 0,-2 ----------------------------------------------------AUAAAGCUAGAUAACCGAAAGU------------- 104 0,0 ----------------------------------------------------AUAAAGCUAGAUAACCGAAAGUu------------ 3 0,0 ----------------------------------------------------AUAAAGCUAGAUAACCGAAAGUA------------ 2 0,1 -----------------------------------------------------UAAAGCUAGAUAACCGAAAGU------------- 5 1,0 -----------------------------------------------------UAAAGCUAGAUAACCGAAAGUA------------ 2 1,1 -----------------------------------------------------UAAAGCUAGAUAACCGAAAGUAA----------- 3 1,2 >hsa-mir-9-3 MA:16-38;mi:55-76 Normal ggaggcccguuucucUCUUUGGUUAUCUAGCUGUAUGAgugccacagagccgucAUAAAGCUAGAUAACCGAAAGUagaaaugauucuca ---------------UCUUUGGUUAUCUAGCUGUA------------------------------------------------------- 4 0,-3 ---------------UCUUUGGUUAUCUAGCUGUAa------------------------------------------------------ 2 0,-3 ---------------UCUUUGGUUAUCUAGCUGUAU------------------------------------------------------ 43 0,-2 ---------------UCUUUGGUUAUCUAGCUGUAUG----------------------------------------------------- 44 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGu---------------------------------------------------- 13 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGA---------------------------------------------------- 159 0,0 ----------------CUUUGGUUAUCUAGCUGUAU------------------------------------------------------ 2 1,-2 ----------------CUUUGGUUAUCUAGCUGUAUG----------------------------------------------------- 3 1,-1 ----------------CUUUGGUUAUCUAGCUGUAUGA---------------------------------------------------- 68 1,0 ----------------CUUUGGUUAUCUAGCUGUAUGAa--------------------------------------------------- 4 1,0 -----------------UUUGGUUAUCUAGCUGUAUGA---------------------------------------------------- 3 2,0 ------------------------------------------------------AUAAAGCUAGAUAACCGA------------------ 2 0,-4 ------------------------------------------------------AUAAAGCUAGAUAACCGAAA---------------- 2 0,-2 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGU-------------- 104 0,0 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGUu------------- 3 0,0 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGUA------------- 2 0,1 -------------------------------------------------------UAAAGCUAGAUAACCGAAAGU-------------- 5 1,0 -------------------------------------------------------UAAAGCUAGAUAACCGAAAGUA------------- 2 1,1 >hsa-mir-92a-1 mi:11-33;MA:48-69 Normal cuuucuacacAGGUUGGGAUCGGUUGCAAUGCUguguuucuguauggUAUUGCACUUGUCCCGGCCUGUugaguuugg ----------AGGUUGGGAUCGGUUGCAAUGC---------------------------------------------- 2 0,-1 ----------AGGUUGGGAUCGGUUGCAAUGCU--------------------------------------------- 75 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGC------------- 4 0,-4 -----------------------------------------------UAUUGCACUUGUCCCGGCC------------ 8 0,-3 -----------------------------------------------UAUUGCACUUGUCCCGGCCU----------- 11 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUaa--------- 2 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUu---------- 2 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUuu--------- 3 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUG---------- 57 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGa--------- 59 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGaa-------- 18 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGU--------- 1212 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUa-------- 155 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUaa------- 94 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUau------- 58 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUc-------- 2 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUU-------- 114 0,1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUUa------- 2 0,1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUUu------- 12 0,1 ------------------------------------------------AUUGCACUUGUCCCGGCC------------ 2 1,-3 ------------------------------------------------AUUGCACUUGUCCCGGCCUG---------- 13 1,-1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGa--------- 6 1,-1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGU--------- 268 1,0 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUa-------- 13 1,0 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUaa------- 14 1,0 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUU-------- 17 1,1 >hsa-mir-92a-2 mi:9-30;MA:48-69 Normal ucaucccuGGGUGGGGAUUUGUUGCAUUACuuguguucuauauaaagUAUUGCACUUGUCCCGGCCUGUggaaga -----------------------------------------------UAUUGCACUUGUCCCGGC---------- 4 0,-4 -----------------------------------------------UAUUGCACUUGUCCCGGCC--------- 8 0,-3 -----------------------------------------------UAUUGCACUUGUCCCGGCCU-------- 11 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUaa------ 2 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUu------- 2 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUuu------ 3 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUG------- 57 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGa------ 59 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGaa----- 18 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGU------ 1212 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUa----- 155 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUaa---- 94 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUau---- 58 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUc----- 2 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUG----- 3 0,1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUGa---- 2 0,1 ------------------------------------------------AUUGCACUUGUCCCGGCC--------- 2 1,-3 ------------------------------------------------AUUGCACUUGUCCCGGCCUG------- 13 1,-1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGa------ 6 1,-1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGU------ 268 1,0 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUa----- 13 1,0 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUaa---- 14 1,0 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUG----- 2 1,1 >hsa-mir-92b mi:20-41;MA:61-82 Normal cgggccccgggcgggcgggAGGGACGGGACGCGGUGCAGUGuuguuuuuucccccgccaaUAUUGCACUCGUCCCGGCCUCCggcccccccggccc -------------------AGGGACGGGACGCGGUGCAGUGU------------------------------------------------------ 7 0,1 -------------------AGGGACGGGACGCGGUGCAGUGUU----------------------------------------------------- 2 0,2 -----------------------------------------------------------AUAUUGCACUCGUCCCGGCCUCC-------------- 2 -1,0 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCU---------------- 2 0,-2 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUC--------------- 2 0,-1 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUCu-------------- 2 0,-1 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUCC-------------- 12 0,0 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUCCa------------- 4 0,0 >hsa-mir-93 MA:11-33;mi:50-71 Normal cugggggcucCAAAGUGCUGUUCGUGCAGGUAGugugauuacccaaccuACUGCUGAGCUAGCACUUCCCGagcccccgg ----------CAAAGUGCUGUUCGUGCA---------------------------------------------------- 45 0,-5 ----------CAAAGUGCUGUUCGUGCAa--------------------------------------------------- 3 0,-5 ----------CAAAGUGCUGUUCGUGCAG--------------------------------------------------- 44 0,-4 ----------CAAAGUGCUGUUCGUGCAGa-------------------------------------------------- 6 0,-4 ----------CAAAGUGCUGUUCGUGCAGu-------------------------------------------------- 2 0,-4 ----------CAAAGUGCUGUUCGUGCAGG-------------------------------------------------- 109 0,-3 ----------CAAAGUGCUGUUCGUGCAGGa------------------------------------------------- 33 0,-3 ----------CAAAGUGCUGUUCGUGCAGGaa------------------------------------------------ 21 0,-3 ----------CAAAGUGCUGUUCGUGCAGGau------------------------------------------------ 2 0,-3 ----------CAAAGUGCUGUUCGUGCAGGc------------------------------------------------- 5 0,-3 ----------CAAAGUGCUGUUCGUGCAGGU------------------------------------------------- 809 0,-2 ----------CAAAGUGCUGUUCGUGCAGGUg------------------------------------------------ 3 0,-2 ----------CAAAGUGCUGUUCGUGCAGGUu------------------------------------------------ 21 0,-2 ----------CAAAGUGCUGUUCGUGCAGGUuu----------------------------------------------- 13 0,-2 ----------CAAAGUGCUGUUCGUGCAGGUA------------------------------------------------ 921 0,-1 ----------CAAAGUGCUGUUCGUGCAGGUAa----------------------------------------------- 350 0,-1 ----------CAAAGUGCUGUUCGUGCAGGUAaa---------------------------------------------- 4 0,-1 ----------CAAAGUGCUGUUCGUGCAGGUAau---------------------------------------------- 5 0,-1 ----------CAAAGUGCUGUUCGUGCAGGUAc----------------------------------------------- 2 0,-1 ----------CAAAGUGCUGUUCGUGCAGGUAu----------------------------------------------- 391 0,-1 ----------CAAAGUGCUGUUCGUGCAGGUAuu---------------------------------------------- 5 0,-1 ----------CAAAGUGCUGUUCGUGCAGGUAG----------------------------------------------- 2978 0,0 ----------CAAAGUGCUGUUCGUGCAGGUAGa---------------------------------------------- 157 0,0 ----------CAAAGUGCUGUUCGUGCAGGUAGaa--------------------------------------------- 5 0,0 ----------CAAAGUGCUGUUCGUGCAGGUAGU---------------------------------------------- 151 0,1 ----------CAAAGUGCUGUUCGUGCAGGUAGUa--------------------------------------------- 4 0,1 -----------AAAGUGCUGUUCGUGCAGG-------------------------------------------------- 11 1,-3 -----------AAAGUGCUGUUCGUGCAGGU------------------------------------------------- 23 1,-2 -----------AAAGUGCUGUUCGUGCAGGUA------------------------------------------------ 38 1,-1 -----------AAAGUGCUGUUCGUGCAGGUAa----------------------------------------------- 13 1,-1 -----------AAAGUGCUGUUCGUGCAGGUAu----------------------------------------------- 8 1,-1 -----------AAAGUGCUGUUCGUGCAGGUAG----------------------------------------------- 122 1,0 -----------AAAGUGCUGUUCGUGCAGGUAGa---------------------------------------------- 11 1,0 -----------AAAGUGCUGUUCGUGCAGGUAGU---------------------------------------------- 2 1,1 -------------------------------------------------ACUGCUGAGCUAGCACUUCC----------- 2 0,-2 -------------------------------------------------ACUGCUGAGCUAGCACUUCCC---------- 4 0,-1 -------------------------------------------------ACUGCUGAGCUAGCACUUCCCG--------- 26 0,0 -------------------------------------------------ACUGCUGAGCUAGCACUUCCCGu-------- 21 0,0 -------------------------------------------------ACUGCUGAGCUAGCACUUCCCGA-------- 70 0,1 --------------------------------------------------CUGCUGAGCUAGCACUUCCCGA-------- 2 1,1 >hsa-mir-934 5pM:15-36 Normal agaaauaaggcuucUGUCUACUACUGGAGACACUGGuaguauaaaacccagagucuccaguaauggacgggagccuuauuucu --------------UGUCUACUACUGGAGACACU------------------------------------------------- 12 0,-2 --------------UGUCUACUACUGGAGACACUG------------------------------------------------ 12 0,-1 --------------UGUCUACUACUGGAGACACUGa----------------------------------------------- 2 0,-1 --------------UGUCUACUACUGGAGACACUGG----------------------------------------------- 20 0,0 --------------UGUCUACUACUGGAGACACUGGa---------------------------------------------- 14 0,0 --------------UGUCUACUACUGGAGACACUGGaa--------------------------------------------- 2 0,0 --------------UGUCUACUACUGGAGACACUGGU---------------------------------------------- 3 0,1 --------------------------------------------------GAGUCUCCAGUAAUGGACGGGu----------- 2 --------------------------------------------------GAGUCUCCAGUAAUGGACGGGA----------- 4 >hsa-mir-939 5pM:15-38 Normal ugugggcagggcccUGGGGAGCUGAGGCUCUGGGGGUGgccggggcugacccugggccucugcuccccagugucugaccgcg --------------UGGGGAGCUGAGGCUCUGGGGGUGu------------------------------------------- 5 0,0 >hsa-mir-940 3pM:60-80 Normal gugaggugugggcccggccccaggagcggggccugggcagccccguguguugaggaaggAAGGCAGGGCCCCCGCUCCCCgggccugaccccac -----------------------------------------------------------AAGGCAGGGCCCCCGCUCCCC-------------- 2 0,0 -----------------------------------------------------------AAGGCAGGGCCCCCGCUCCCCu------------- 9 0,0 >hsa-mir-941-1 3pM:71-93 Normal cacggaagaggacacacccggcuguguggacaugugcccagggcccgggacagcgccacggaagaggacgCACCCGGCUGUGUGCACAUGUGCccagggcccgggacagcgccacgg ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUG------------------------- 4 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGa------------------------ 3 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGu------------------------ 2 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGC------------------------ 28 0,0 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGCu----------------------- 3 0,0 >hsa-mir-941-2 3pM:71-93 Normal cacggaagaggacgcacccggcugugugcacaugugcccagggcccgggacagcgccacggaagaggacgCACCCGGCUGUGUGCACAUGUGCccagggcccgggacagcgccacgg --------------CACCCGGCUGUGUGCACAUGUG--------------------------------------------------------------------------------- 4 --------------CACCCGGCUGUGUGCACAUGUGa-------------------------------------------------------------------------------- 3 --------------CACCCGGCUGUGUGCACAUGUGu-------------------------------------------------------------------------------- 2 --------------CACCCGGCUGUGUGCACAUGUGC-------------------------------------------------------------------------------- 28 --------------CACCCGGCUGUGUGCACAUGUGCu------------------------------------------------------------------------------- 3 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUG------------------------- 4 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGa------------------------ 3 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGu------------------------ 2 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGC------------------------ 28 0,0 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGCu----------------------- 3 0,0 >hsa-mir-941-3 3pM:71-93 Normal cacggaagaggacgcacccggcugugugcacaugugcccagggcccgggacagcgccacggaagaggacgCACCCGGCUGUGUGCACAUGUGCccagggcccgggacagcgccaugg --------------CACCCGGCUGUGUGCACAUGUG--------------------------------------------------------------------------------- 4 --------------CACCCGGCUGUGUGCACAUGUGa-------------------------------------------------------------------------------- 3 --------------CACCCGGCUGUGUGCACAUGUGu-------------------------------------------------------------------------------- 2 --------------CACCCGGCUGUGUGCACAUGUGC-------------------------------------------------------------------------------- 28 --------------CACCCGGCUGUGUGCACAUGUGCu------------------------------------------------------------------------------- 3 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUG------------------------- 4 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGa------------------------ 3 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGu------------------------ 2 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGC------------------------ 28 0,0 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGCu----------------------- 3 0,0 >hsa-mir-941-4 3pM:71-93 Normal cauggaagaggacgcacccggcugugugcacaugugcccagggcccgggacagcgccacggaagaggacgCACCCGGCUGUGUGCACAUGUGCccagggcccgggacagcgccacgg --------------CACCCGGCUGUGUGCACAUGUG--------------------------------------------------------------------------------- 4 --------------CACCCGGCUGUGUGCACAUGUGa-------------------------------------------------------------------------------- 3 --------------CACCCGGCUGUGUGCACAUGUGu-------------------------------------------------------------------------------- 2 --------------CACCCGGCUGUGUGCACAUGUGC-------------------------------------------------------------------------------- 28 --------------CACCCGGCUGUGUGCACAUGUGCu------------------------------------------------------------------------------- 3 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUG------------------------- 4 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGa------------------------ 3 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGu------------------------ 2 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGC------------------------ 28 0,0 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGCu----------------------- 3 0,0 >hsa-mir-942 5pM:13-34 Normal auuaggagaguaUCUUCUCUGUUUUGGCCAUGUGuguacucacagccccucacacauggccgaaacagagaaguuacuuuccuaau ------------UCUUCUCUGUUUUGGCCAUGUG---------------------------------------------------- 2 0,0 ------------UCUUCUCUGUUUUGGCCAUGUGa--------------------------------------------------- 2 0,0 >hsa-mir-944 3pM:54-75 Normal guuccagacacaucucaucugauauacaauauuuucuuaaauuguauaaagagAAAUUAUUGUACAUCGGAUGAGcugugucugggau ----------------------------------------------------GAAAUUAUUGUACAUCGGAUGAGa------------ 2 -1,0 ------------------------------------------------------AAUUAUUGUACAUCGGAUGAGa------------ 2 1,0 ------------------------------------------------------AAUUAUUGUACAUCGGAUGAGu------------ 2 1,0 >hsa-mir-95 3pM:49-70 Normal aacacagugggcacucaauaaaugucuguugaauugaaaugcguuacaUUCAACGGGUAUUUAUUGAGCAcccacucugug ------------------------------------------------UUCAACGGGUAUUUAUUGAGC------------ 10 0,-1 ------------------------------------------------UUCAACGGGUAUUUAUUGAGCA----------- 6 0,0 >hsa-mir-96 MA:9-31;mi:52-73 Normal uggccgauUUUGGCACUAGCACAUUUUUGCUugugucucuccgcucugagcAAUCAUGUGCAGUGCCAAUAUGggaaa --------UUUGGCACUAGCACAUUUU--------------------------------------------------- 2 0,-4 --------UUUGGCACUAGCACAUUUUU-------------------------------------------------- 2 0,-3 --------UUUGGCACUAGCACAUUUUUG------------------------------------------------- 44 0,-2 --------UUUGGCACUAGCACAUUUUUGa------------------------------------------------ 4 0,-2 --------UUUGGCACUAGCACAUUUUUGu------------------------------------------------ 2 0,-2 --------UUUGGCACUAGCACAUUUUUGC------------------------------------------------ 21 0,-1 --------UUUGGCACUAGCACAUUUUUGCU----------------------------------------------- 177 0,0 --------UUUGGCACUAGCACAUUUUUGCUa---------------------------------------------- 2 0,0 ---------UUGGCACUAGCACAUUUUUGCU----------------------------------------------- 2 1,0 >hsa-mir-98 5pM:22-43 Normal aggauucugcucaugccagggUGAGGUAGUAAGUUGUAUUGUUgugggguagggauauuaggccccaauuagaagauaacuauacaacuuacuacuuucccugguguguggcauauuca ---------------------UGAGGUAGUAAGUUGUAU-------------------------------------------------------------------------------- 113 0,-4 ---------------------UGAGGUAGUAAGUUGUAUU------------------------------------------------------------------------------- 4 0,-3 ---------------------UGAGGUAGUAAGUUGUAUUG------------------------------------------------------------------------------ 12 0,-2 ---------------------UGAGGUAGUAAGUUGUAUUGa----------------------------------------------------------------------------- 2 0,-2 ---------------------UGAGGUAGUAAGUUGUAUUGU----------------------------------------------------------------------------- 119 0,-1 ---------------------UGAGGUAGUAAGUUGUAUUGUa---------------------------------------------------------------------------- 4 0,-1 ---------------------UGAGGUAGUAAGUUGUAUUGUU---------------------------------------------------------------------------- 464 0,0 ---------------------UGAGGUAGUAAGUUGUAUUGUUa--------------------------------------------------------------------------- 22 0,0 ---------------------UGAGGUAGUAAGUUGUAUUGUUu--------------------------------------------------------------------------- 8 0,0 ----------------------GAGGUAGUAAGUUGUAUUGU----------------------------------------------------------------------------- 2 1,-1 ----------------------GAGGUAGUAAGUUGUAUUGUU---------------------------------------------------------------------------- 16 1,0 -------------------------------------------------------------------------------CUAUACAACUUACUACUUUC-------------------- 5 -------------------------------------------------------------------------------CUAUACAACUUACUACUUUCC------------------- 2 -------------------------------------------------------------------------------CUAUACAACUUACUACUUUCCu------------------ 5 --------------------------------------------------------------------------------UAUACAACUUACUACUUUCCuu----------------- 2 >hsa-mir-99a MA:13-34;mi:50-71 Normal cccauuggcauaAACCCGUAGAUCCGAUCUUGUGgugaaguggaccgcaCAAGCUCGCUUCUAUGGGUCUGugucagugug -----------AAACCCGUAGAUCCGAUCUUG------------------------------------------------- 13 -1,-2 -----------AAACCCGUAGAUCCGAUCUUGc------------------------------------------------ 2 -1,-2 -----------AAACCCGUAGAUCCGAUCUUGU------------------------------------------------ 592 -1,-1 -----------AAACCCGUAGAUCCGAUCUUGUa----------------------------------------------- 5 -1,-1 -----------AAACCCGUAGAUCCGAUCUUGUG----------------------------------------------- 30 -1,0 -----------AAACCCGUAGAUCCGAUCUUGUGa---------------------------------------------- 4 -1,0 -----------AAACCCGUAGAUCCGAUCUUGUGu---------------------------------------------- 7 -1,0 ------------AACCCGUAGAUCCGAUCU--------------------------------------------------- 657 0,-4 ------------AACCCGUAGAUCCGAUCUa-------------------------------------------------- 14 0,-4 ------------AACCCGUAGAUCCGAUCUU-------------------------------------------------- 683 0,-3 ------------AACCCGUAGAUCCGAUCUUa------------------------------------------------- 5 0,-3 ------------AACCCGUAGAUCCGAUCUUau------------------------------------------------ 50 0,-3 ------------AACCCGUAGAUCCGAUCUUc------------------------------------------------- 2 0,-3 ------------AACCCGUAGAUCCGAUCUUu------------------------------------------------- 8 0,-3 ------------AACCCGUAGAUCCGAUCUUuu------------------------------------------------ 32 0,-3 ------------AACCCGUAGAUCCGAUCUUG------------------------------------------------- 2180 0,-2 ------------AACCCGUAGAUCCGAUCUUGa------------------------------------------------ 191 0,-2 ------------AACCCGUAGAUCCGAUCUUGaa----------------------------------------------- 11 0,-2 ------------AACCCGUAGAUCCGAUCUUGau----------------------------------------------- 2 0,-2 ------------AACCCGUAGAUCCGAUCUUGc------------------------------------------------ 84 0,-2 ------------AACCCGUAGAUCCGAUCUUGg------------------------------------------------ 51 0,-2 ------------AACCCGUAGAUCCGAUCUUGU------------------------------------------------ 32441 0,-1 ------------AACCCGUAGAUCCGAUCUUGUa----------------------------------------------- 337 0,-1 ------------AACCCGUAGAUCCGAUCUUGUaa---------------------------------------------- 55 0,-1 ------------AACCCGUAGAUCCGAUCUUGUau---------------------------------------------- 16 0,-1 ------------AACCCGUAGAUCCGAUCUUGUc----------------------------------------------- 14 0,-1 ------------AACCCGUAGAUCCGAUCUUGUu----------------------------------------------- 146 0,-1 ------------AACCCGUAGAUCCGAUCUUGUuu---------------------------------------------- 30 0,-1 ------------AACCCGUAGAUCCGAUCUUGUG----------------------------------------------- 17604 0,0 ------------AACCCGUAGAUCCGAUCUUGUGa---------------------------------------------- 17333 0,0 ------------AACCCGUAGAUCCGAUCUUGUGaa--------------------------------------------- 238 0,0 ------------AACCCGUAGAUCCGAUCUUGUGau--------------------------------------------- 28 0,0 ------------AACCCGUAGAUCCGAUCUUGUGc---------------------------------------------- 82 0,0 ------------AACCCGUAGAUCCGAUCUUGUGu---------------------------------------------- 11306 0,0 ------------AACCCGUAGAUCCGAUCUUGUGuu--------------------------------------------- 6 0,0 ------------AACCCGUAGAUCCGAUCUUGUGG---------------------------------------------- 170 0,1 ------------AACCCGUAGAUCCGAUCUUGUGGU--------------------------------------------- 4 0,2 -------------ACCCGUAGAUCCGAUCUU-------------------------------------------------- 13 1,-3 -------------ACCCGUAGAUCCGAUCUUau------------------------------------------------ 2 1,-3 -------------ACCCGUAGAUCCGAUCUUuu------------------------------------------------ 2 1,-3 -------------ACCCGUAGAUCCGAUCUUG------------------------------------------------- 48 1,-2 -------------ACCCGUAGAUCCGAUCUUGa------------------------------------------------ 6 1,-2 -------------ACCCGUAGAUCCGAUCUUGU------------------------------------------------ 1107 1,-1 -------------ACCCGUAGAUCCGAUCUUGUa----------------------------------------------- 12 1,-1 -------------ACCCGUAGAUCCGAUCUUGUaa---------------------------------------------- 4 1,-1 -------------ACCCGUAGAUCCGAUCUUGUu----------------------------------------------- 16 1,-1 -------------ACCCGUAGAUCCGAUCUUGUuu---------------------------------------------- 2 1,-1 -------------ACCCGUAGAUCCGAUCUUGUG----------------------------------------------- 611 1,0 -------------ACCCGUAGAUCCGAUCUUGUGa---------------------------------------------- 734 1,0 -------------ACCCGUAGAUCCGAUCUUGUGaa--------------------------------------------- 4 1,0 -------------ACCCGUAGAUCCGAUCUUGUGu---------------------------------------------- 368 1,0 --------------CCCGUAGAUCCGAUCUUGU------------------------------------------------ 2 2,-1 --------------CCCGUAGAUCCGAUCUUGUGa---------------------------------------------- 2 2,0 -------------------------------------------------CAAGCUCGCUUCUAUGGGU------------- 11 0,-3 -------------------------------------------------CAAGCUCGCUUCUAUGGGUC------------ 7 0,-2 -------------------------------------------------CAAGCUCGCUUCUAUGGGUCU----------- 69 0,-1 -------------------------------------------------CAAGCUCGCUUCUAUGGGUCUG---------- 25 0,0 -------------------------------------------------CAAGCUCGCUUCUAUGGGUCUGa--------- 28 0,0 -------------------------------------------------CAAGCUCGCUUCUAUGGGUCUGau-------- 2 0,0 -------------------------------------------------CAAGCUCGCUUCUAUGGGUCUGU--------- 82 0,1 -------------------------------------------------CAAGCUCGCUUCUAUGGGUCUGUa-------- 2 0,1 -------------------------------------------------CAAGCUCGCUUCUAUGGGUCUGUu-------- 5 0,1 --------------------------------------------------AAGCUCGCUUCUAUGGGUCU----------- 4 1,-1 --------------------------------------------------AAGCUCGCUUCUAUGGGUCUGU--------- 3 1,1 >hsa-mir-99b MA:7-28;mi:45-66 Normal ggcaccCACCCGUAGAACCGACCUUGCGgggccuucgccgcacaCAAGCUCGUGUCUGUGGGUCCGuguc -----CCACCCGUAGAACCGACCUUGC------------------------------------------- 2 -1,-1 ------CACCCGUAGAACCGACCU---------------------------------------------- 15 0,-4 ------CACCCGUAGAACCGACCUU--------------------------------------------- 36 0,-3 ------CACCCGUAGAACCGACCUUG-------------------------------------------- 143 0,-2 ------CACCCGUAGAACCGACCUUGa------------------------------------------- 15 0,-2 ------CACCCGUAGAACCGACCUUGu------------------------------------------- 7 0,-2 ------CACCCGUAGAACCGACCUUGC------------------------------------------- 777 0,-1 ------CACCCGUAGAACCGACCUUGCa------------------------------------------ 33 0,-1 ------CACCCGUAGAACCGACCUUGCaa----------------------------------------- 3 0,-1 ------CACCCGUAGAACCGACCUUGCu------------------------------------------ 7 0,-1 ------CACCCGUAGAACCGACCUUGCG------------------------------------------ 2030 0,0 ------CACCCGUAGAACCGACCUUGCGa----------------------------------------- 460 0,0 ------CACCCGUAGAACCGACCUUGCGaa---------------------------------------- 2 0,0 ------CACCCGUAGAACCGACCUUGCGau---------------------------------------- 8 0,0 ------CACCCGUAGAACCGACCUUGCGu----------------------------------------- 164 0,0 ------CACCCGUAGAACCGACCUUGCGG----------------------------------------- 3 0,1 -------ACCCGUAGAACCGACCUUG-------------------------------------------- 6 1,-2 -------ACCCGUAGAACCGACCUUGC------------------------------------------- 28 1,-1 -------ACCCGUAGAACCGACCUUGCG------------------------------------------ 90 1,0 -------ACCCGUAGAACCGACCUUGCGa----------------------------------------- 29 1,0 -------ACCCGUAGAACCGACCUUGCGu----------------------------------------- 2 1,0 --------------------------------------------CAAGCUCGUGUCUGUGGGU------- 5 0,-3 --------------------------------------------CAAGCUCGUGUCUGUGGGUC------ 5 0,-2 --------------------------------------------CAAGCUCGUGUCUGUGGGUCau---- 2 0,-2 --------------------------------------------CAAGCUCGUGUCUGUGGGUCC----- 4 0,-1 --------------------------------------------CAAGCUCGUGUCUGUGGGUCCG---- 17 0,0 --------------------------------------------CAAGCUCGUGUCUGUGGGUCCGa--- 40 0,0 --------------------------------------------CAAGCUCGUGUCUGUGGGUCCGau-- 3 0,0 --------------------------------------------CAAGCUCGUGUCUGUGGGUCCGU--- 23 0,1 --------------------------------------------CAAGCUCGUGUCUGUGGGUCCGUu-- 9 0,1 >hsa-let-7a-1 MA:6-27;mi:57-77 Tumor ugggaUGAGGUAGUAGGUUGUAUAGUUuuagggucacacccaccacugggagauaaCUAUACAAUCUACUGUCUUUCcua ----AUGAGGUAGUAGGUUGUAU--------------------------------------------------------- 2 -1,-4 ----AUGAGGUAGUAGGUUGUAUAGU------------------------------------------------------ 7 -1,-1 ----AUGAGGUAGUAGGUUGUAUAGUU----------------------------------------------------- 39 -1,0 -----UGAGGUAGUAGGUUGUAU--------------------------------------------------------- 9800 0,-4 -----UGAGGUAGUAGGUUGUAUu-------------------------------------------------------- 161 0,-4 -----UGAGGUAGUAGGUUGUAUuu------------------------------------------------------- 40 0,-4 -----UGAGGUAGUAGGUUGUAUA-------------------------------------------------------- 6486 0,-3 -----UGAGGUAGUAGGUUGUAUAa------------------------------------------------------- 1300 0,-3 -----UGAGGUAGUAGGUUGUAUAaa------------------------------------------------------ 275 0,-3 -----UGAGGUAGUAGGUUGUAUAau------------------------------------------------------ 435 0,-3 -----UGAGGUAGUAGGUUGUAUAc------------------------------------------------------- 4 0,-3 -----UGAGGUAGUAGGUUGUAUAu------------------------------------------------------- 311 0,-3 -----UGAGGUAGUAGGUUGUAUAuu------------------------------------------------------ 723 0,-3 -----UGAGGUAGUAGGUUGUAUAG------------------------------------------------------- 33274 0,-2 -----UGAGGUAGUAGGUUGUAUAGa------------------------------------------------------ 4394 0,-2 -----UGAGGUAGUAGGUUGUAUAGaa----------------------------------------------------- 629 0,-2 -----UGAGGUAGUAGGUUGUAUAGau----------------------------------------------------- 309 0,-2 -----UGAGGUAGUAGGUUGUAUAGc------------------------------------------------------ 395 0,-2 -----UGAGGUAGUAGGUUGUAUAGg------------------------------------------------------ 258 0,-2 -----UGAGGUAGUAGGUUGUAUAGU------------------------------------------------------ 246861 0,-1 -----UGAGGUAGUAGGUUGUAUAGUa----------------------------------------------------- 8810 0,-1 -----UGAGGUAGUAGGUUGUAUAGUaa---------------------------------------------------- 3293 0,-1 -----UGAGGUAGUAGGUUGUAUAGUau---------------------------------------------------- 933 0,-1 -----UGAGGUAGUAGGUUGUAUAGUc----------------------------------------------------- 1109 0,-1 -----UGAGGUAGUAGGUUGUAUAGUg----------------------------------------------------- 358 0,-1 -----UGAGGUAGUAGGUUGUAUAGUU----------------------------------------------------- 774572 0,0 -----UGAGGUAGUAGGUUGUAUAGUUa---------------------------------------------------- 39025 0,0 -----UGAGGUAGUAGGUUGUAUAGUUaa--------------------------------------------------- 1401 0,0 -----UGAGGUAGUAGGUUGUAUAGUUau--------------------------------------------------- 833 0,0 -----UGAGGUAGUAGGUUGUAUAGUUc---------------------------------------------------- 412 0,0 -----UGAGGUAGUAGGUUGUAUAGUUg---------------------------------------------------- 2420 0,0 -----UGAGGUAGUAGGUUGUAUAGUUU---------------------------------------------------- 41070 0,1 -----UGAGGUAGUAGGUUGUAUAGUUUc--------------------------------------------------- 2 0,1 -----UGAGGUAGUAGGUUGUAUAGUUUU--------------------------------------------------- 645 0,2 -----UGAGGUAGUAGGUUGUAUAGUUUUu-------------------------------------------------- 10 0,2 ------GAGGUAGUAGGUUGUAUA-------------------------------------------------------- 82 1,-3 ------GAGGUAGUAGGUUGUAUAa------------------------------------------------------- 10 1,-3 ------GAGGUAGUAGGUUGUAUAau------------------------------------------------------ 7 1,-3 ------GAGGUAGUAGGUUGUAUAu------------------------------------------------------- 4 1,-3 ------GAGGUAGUAGGUUGUAUAuu------------------------------------------------------ 12 1,-3 ------GAGGUAGUAGGUUGUAUAG------------------------------------------------------- 783 1,-2 ------GAGGUAGUAGGUUGUAUAGa------------------------------------------------------ 102 1,-2 ------GAGGUAGUAGGUUGUAUAGaa----------------------------------------------------- 8 1,-2 ------GAGGUAGUAGGUUGUAUAGau----------------------------------------------------- 4 1,-2 ------GAGGUAGUAGGUUGUAUAGc------------------------------------------------------ 6 1,-2 ------GAGGUAGUAGGUUGUAUAGU------------------------------------------------------ 7044 1,-1 ------GAGGUAGUAGGUUGUAUAGUa----------------------------------------------------- 254 1,-1 ------GAGGUAGUAGGUUGUAUAGUaa---------------------------------------------------- 67 1,-1 ------GAGGUAGUAGGUUGUAUAGUau---------------------------------------------------- 6 1,-1 ------GAGGUAGUAGGUUGUAUAGUc----------------------------------------------------- 12 1,-1 ------GAGGUAGUAGGUUGUAUAGUg----------------------------------------------------- 2 1,-1 ------GAGGUAGUAGGUUGUAUAGUU----------------------------------------------------- 21516 1,0 ------GAGGUAGUAGGUUGUAUAGUUa---------------------------------------------------- 1086 1,0 ------GAGGUAGUAGGUUGUAUAGUUaa--------------------------------------------------- 18 1,0 ------GAGGUAGUAGGUUGUAUAGUUau--------------------------------------------------- 12 1,0 ------GAGGUAGUAGGUUGUAUAGUUc---------------------------------------------------- 4 1,0 ------GAGGUAGUAGGUUGUAUAGUUg---------------------------------------------------- 40 1,0 ------GAGGUAGUAGGUUGUAUAGUUU---------------------------------------------------- 1136 1,1 ------GAGGUAGUAGGUUGUAUAGUUUU--------------------------------------------------- 2 1,2 -------AGGUAGUAGGUUGUAUAG------------------------------------------------------- 12 2,-2 -------AGGUAGUAGGUUGUAUAGU------------------------------------------------------ 196 2,-1 -------AGGUAGUAGGUUGUAUAGUa----------------------------------------------------- 5 2,-1 -------AGGUAGUAGGUUGUAUAGUU----------------------------------------------------- 770 2,0 -------AGGUAGUAGGUUGUAUAGUUa---------------------------------------------------- 29 2,0 -------AGGUAGUAGGUUGUAUAGUUU---------------------------------------------------- 38 2,1 --------------------------------------------------------CUAUACAAUCUACUGUCUU----- 11 0,-2 --------------------------------------------------------CUAUACAAUCUACUGUCUUau--- 2 0,-2 --------------------------------------------------------CUAUACAAUCUACUGUCUUU---- 841 0,-1 --------------------------------------------------------CUAUACAAUCUACUGUCUUUa--- 2 0,-1 --------------------------------------------------------CUAUACAAUCUACUGUCUUUau-- 2 0,-1 --------------------------------------------------------CUAUACAAUCUACUGUCUUUu--- 35 0,-1 --------------------------------------------------------CUAUACAAUCUACUGUCUUUuu-- 28 0,-1 --------------------------------------------------------CUAUACAAUCUACUGUCUUUC--- 1236 0,0 --------------------------------------------------------CUAUACAAUCUACUGUCUUUCa-- 49 0,0 --------------------------------------------------------CUAUACAAUCUACUGUCUUUCu-- 2077 0,0 --------------------------------------------------------CUAUACAAUCUACUGUCUUUCuu- 2 0,0 --------------------------------------------------------CUAUACAAUCUACUGUCUUUCC-- 772 0,1 --------------------------------------------------------CUAUACAAUCUACUGUCUUUCCa- 35 0,1 --------------------------------------------------------CUAUACAAUCUACUGUCUUUCCU- 5 0,2 ---------------------------------------------------------UAUACAAUCUACUGUCUUU---- 22 1,-1 ---------------------------------------------------------UAUACAAUCUACUGUCUUUC--- 38 1,0 ---------------------------------------------------------UAUACAAUCUACUGUCUUUCu-- 46 1,0 ---------------------------------------------------------UAUACAAUCUACUGUCUUUCC-- 36 1,1 ---------------------------------------------------------UAUACAAUCUACUGUCUUUCCa- 2 1,1 ---------------------------------------------------------UAUACAAUCUACUGUCUUUCCU- 54 1,2 ---------------------------------------------------------UAUACAAUCUACUGUCUUUCCUu 2 1,2 ----------------------------------------------------------AUACAAUCUACUGUCUUUC--- 6 2,0 ----------------------------------------------------------AUACAAUCUACUGUCUUUCu-- 2 2,0 ----------------------------------------------------------AUACAAUCUACUGUCUUUCC-- 4 2,1 ----------------------------------------------------------AUACAAUCUACUGUCUUUCCU- 13 2,2 >hsa-let-7a-2 MA:5-26;mi:50-71 Tumor agguUGAGGUAGUAGGUUGUAUAGUUuagaauuacaucaagggagauaaCUGUACAGCCUCCUAGCUUUCCu ---UUGAGGUAGUAGGUUGUAUAGU----------------------------------------------- 4 -1,-1 ---UUGAGGUAGUAGGUUGUAUAGUU---------------------------------------------- 28 -1,0 ---UUGAGGUAGUAGGUUGUAUAGUUa--------------------------------------------- 2 -1,0 ----UGAGGUAGUAGGUUGUAU-------------------------------------------------- 9800 0,-4 ----UGAGGUAGUAGGUUGUAUu------------------------------------------------- 161 0,-4 ----UGAGGUAGUAGGUUGUAUuu------------------------------------------------ 40 0,-4 ----UGAGGUAGUAGGUUGUAUA------------------------------------------------- 6486 0,-3 ----UGAGGUAGUAGGUUGUAUAa------------------------------------------------ 1300 0,-3 ----UGAGGUAGUAGGUUGUAUAaa----------------------------------------------- 275 0,-3 ----UGAGGUAGUAGGUUGUAUAau----------------------------------------------- 435 0,-3 ----UGAGGUAGUAGGUUGUAUAc------------------------------------------------ 4 0,-3 ----UGAGGUAGUAGGUUGUAUAu------------------------------------------------ 311 0,-3 ----UGAGGUAGUAGGUUGUAUAuu----------------------------------------------- 723 0,-3 ----UGAGGUAGUAGGUUGUAUAG------------------------------------------------ 33274 0,-2 ----UGAGGUAGUAGGUUGUAUAGa----------------------------------------------- 4394 0,-2 ----UGAGGUAGUAGGUUGUAUAGaa---------------------------------------------- 629 0,-2 ----UGAGGUAGUAGGUUGUAUAGau---------------------------------------------- 309 0,-2 ----UGAGGUAGUAGGUUGUAUAGc----------------------------------------------- 395 0,-2 ----UGAGGUAGUAGGUUGUAUAGg----------------------------------------------- 258 0,-2 ----UGAGGUAGUAGGUUGUAUAGU----------------------------------------------- 246861 0,-1 ----UGAGGUAGUAGGUUGUAUAGUa---------------------------------------------- 8810 0,-1 ----UGAGGUAGUAGGUUGUAUAGUaa--------------------------------------------- 3293 0,-1 ----UGAGGUAGUAGGUUGUAUAGUau--------------------------------------------- 933 0,-1 ----UGAGGUAGUAGGUUGUAUAGUc---------------------------------------------- 1109 0,-1 ----UGAGGUAGUAGGUUGUAUAGUg---------------------------------------------- 358 0,-1 ----UGAGGUAGUAGGUUGUAUAGUU---------------------------------------------- 774572 0,0 ----UGAGGUAGUAGGUUGUAUAGUUa--------------------------------------------- 39025 0,0 ----UGAGGUAGUAGGUUGUAUAGUUaa-------------------------------------------- 1401 0,0 ----UGAGGUAGUAGGUUGUAUAGUUau-------------------------------------------- 833 0,0 ----UGAGGUAGUAGGUUGUAUAGUUc--------------------------------------------- 412 0,0 ----UGAGGUAGUAGGUUGUAUAGUUg--------------------------------------------- 2420 0,0 ----UGAGGUAGUAGGUUGUAUAGUUU--------------------------------------------- 41070 0,1 ----UGAGGUAGUAGGUUGUAUAGUUUc-------------------------------------------- 2 0,1 ----UGAGGUAGUAGGUUGUAUAGUUUA-------------------------------------------- 146 0,2 -----GAGGUAGUAGGUUGUAUA------------------------------------------------- 82 1,-3 -----GAGGUAGUAGGUUGUAUAa------------------------------------------------ 10 1,-3 -----GAGGUAGUAGGUUGUAUAau----------------------------------------------- 7 1,-3 -----GAGGUAGUAGGUUGUAUAu------------------------------------------------ 4 1,-3 -----GAGGUAGUAGGUUGUAUAuu----------------------------------------------- 12 1,-3 -----GAGGUAGUAGGUUGUAUAG------------------------------------------------ 783 1,-2 -----GAGGUAGUAGGUUGUAUAGa----------------------------------------------- 102 1,-2 -----GAGGUAGUAGGUUGUAUAGaa---------------------------------------------- 8 1,-2 -----GAGGUAGUAGGUUGUAUAGau---------------------------------------------- 4 1,-2 -----GAGGUAGUAGGUUGUAUAGc----------------------------------------------- 6 1,-2 -----GAGGUAGUAGGUUGUAUAGU----------------------------------------------- 7044 1,-1 -----GAGGUAGUAGGUUGUAUAGUa---------------------------------------------- 254 1,-1 -----GAGGUAGUAGGUUGUAUAGUaa--------------------------------------------- 67 1,-1 -----GAGGUAGUAGGUUGUAUAGUau--------------------------------------------- 6 1,-1 -----GAGGUAGUAGGUUGUAUAGUc---------------------------------------------- 12 1,-1 -----GAGGUAGUAGGUUGUAUAGUg---------------------------------------------- 2 1,-1 -----GAGGUAGUAGGUUGUAUAGUU---------------------------------------------- 21516 1,0 -----GAGGUAGUAGGUUGUAUAGUUa--------------------------------------------- 1086 1,0 -----GAGGUAGUAGGUUGUAUAGUUaa-------------------------------------------- 18 1,0 -----GAGGUAGUAGGUUGUAUAGUUau-------------------------------------------- 12 1,0 -----GAGGUAGUAGGUUGUAUAGUUc--------------------------------------------- 4 1,0 -----GAGGUAGUAGGUUGUAUAGUUg--------------------------------------------- 40 1,0 -----GAGGUAGUAGGUUGUAUAGUUU--------------------------------------------- 1136 1,1 ------AGGUAGUAGGUUGUAUAG------------------------------------------------ 12 2,-2 ------AGGUAGUAGGUUGUAUAGU----------------------------------------------- 196 2,-1 ------AGGUAGUAGGUUGUAUAGUa---------------------------------------------- 5 2,-1 ------AGGUAGUAGGUUGUAUAGUU---------------------------------------------- 770 2,0 ------AGGUAGUAGGUUGUAUAGUUa--------------------------------------------- 29 2,0 ------AGGUAGUAGGUUGUAUAGUUU--------------------------------------------- 38 2,1 -------------------------------------------------CUGUACAGCCUCCUAGCUUU--- 2 0,-2 -------------------------------------------------CUGUACAGCCUCCUAGCUUUC-- 4 0,-1 -------------------------------------------------CUGUACAGCCUCCUAGCUUUCC- 8 0,0 >hsa-let-7a-3 MA:4-25;mi:52-72 Tumor gggUGAGGUAGUAGGUUGUAUAGUUuggggcucugcccugcuaugggauaaCUAUACAAUCUACUGUCUUUCcu --GUGAGGUAGUAGGUUGUA------------------------------------------------------ 2 -1,-5 --GUGAGGUAGUAGGUUGUAU----------------------------------------------------- 15 -1,-4 --GUGAGGUAGUAGGUUGUAUA---------------------------------------------------- 5 -1,-3 --GUGAGGUAGUAGGUUGUAUAG--------------------------------------------------- 142 -1,-2 --GUGAGGUAGUAGGUUGUAUAGa-------------------------------------------------- 6 -1,-2 --GUGAGGUAGUAGGUUGUAUAGc-------------------------------------------------- 2 -1,-2 --GUGAGGUAGUAGGUUGUAUAGU-------------------------------------------------- 1506 -1,-1 --GUGAGGUAGUAGGUUGUAUAGUa------------------------------------------------- 9 -1,-1 --GUGAGGUAGUAGGUUGUAUAGUU------------------------------------------------- 1269 -1,0 --GUGAGGUAGUAGGUUGUAUAGUUU------------------------------------------------ 23 -1,1 ---UGAGGUAGUAGGUUGUAU----------------------------------------------------- 9800 0,-4 ---UGAGGUAGUAGGUUGUAUu---------------------------------------------------- 161 0,-4 ---UGAGGUAGUAGGUUGUAUuu--------------------------------------------------- 40 0,-4 ---UGAGGUAGUAGGUUGUAUA---------------------------------------------------- 6486 0,-3 ---UGAGGUAGUAGGUUGUAUAa--------------------------------------------------- 1300 0,-3 ---UGAGGUAGUAGGUUGUAUAaa-------------------------------------------------- 275 0,-3 ---UGAGGUAGUAGGUUGUAUAau-------------------------------------------------- 435 0,-3 ---UGAGGUAGUAGGUUGUAUAc--------------------------------------------------- 4 0,-3 ---UGAGGUAGUAGGUUGUAUAu--------------------------------------------------- 311 0,-3 ---UGAGGUAGUAGGUUGUAUAuu-------------------------------------------------- 723 0,-3 ---UGAGGUAGUAGGUUGUAUAG--------------------------------------------------- 33274 0,-2 ---UGAGGUAGUAGGUUGUAUAGa-------------------------------------------------- 4394 0,-2 ---UGAGGUAGUAGGUUGUAUAGaa------------------------------------------------- 629 0,-2 ---UGAGGUAGUAGGUUGUAUAGau------------------------------------------------- 309 0,-2 ---UGAGGUAGUAGGUUGUAUAGc-------------------------------------------------- 395 0,-2 ---UGAGGUAGUAGGUUGUAUAGg-------------------------------------------------- 258 0,-2 ---UGAGGUAGUAGGUUGUAUAGU-------------------------------------------------- 246861 0,-1 ---UGAGGUAGUAGGUUGUAUAGUa------------------------------------------------- 8810 0,-1 ---UGAGGUAGUAGGUUGUAUAGUaa------------------------------------------------ 3293 0,-1 ---UGAGGUAGUAGGUUGUAUAGUau------------------------------------------------ 933 0,-1 ---UGAGGUAGUAGGUUGUAUAGUc------------------------------------------------- 1109 0,-1 ---UGAGGUAGUAGGUUGUAUAGUg------------------------------------------------- 358 0,-1 ---UGAGGUAGUAGGUUGUAUAGUU------------------------------------------------- 774572 0,0 ---UGAGGUAGUAGGUUGUAUAGUUa------------------------------------------------ 39025 0,0 ---UGAGGUAGUAGGUUGUAUAGUUaa----------------------------------------------- 1401 0,0 ---UGAGGUAGUAGGUUGUAUAGUUau----------------------------------------------- 833 0,0 ---UGAGGUAGUAGGUUGUAUAGUUc------------------------------------------------ 412 0,0 ---UGAGGUAGUAGGUUGUAUAGUUg------------------------------------------------ 2420 0,0 ---UGAGGUAGUAGGUUGUAUAGUUU------------------------------------------------ 41070 0,1 ---UGAGGUAGUAGGUUGUAUAGUUUc----------------------------------------------- 2 0,1 ---UGAGGUAGUAGGUUGUAUAGUUUG----------------------------------------------- 4 0,2 ----GAGGUAGUAGGUUGUAUA---------------------------------------------------- 82 1,-3 ----GAGGUAGUAGGUUGUAUAa--------------------------------------------------- 10 1,-3 ----GAGGUAGUAGGUUGUAUAau-------------------------------------------------- 7 1,-3 ----GAGGUAGUAGGUUGUAUAu--------------------------------------------------- 4 1,-3 ----GAGGUAGUAGGUUGUAUAuu-------------------------------------------------- 12 1,-3 ----GAGGUAGUAGGUUGUAUAG--------------------------------------------------- 783 1,-2 ----GAGGUAGUAGGUUGUAUAGa-------------------------------------------------- 102 1,-2 ----GAGGUAGUAGGUUGUAUAGaa------------------------------------------------- 8 1,-2 ----GAGGUAGUAGGUUGUAUAGau------------------------------------------------- 4 1,-2 ----GAGGUAGUAGGUUGUAUAGc-------------------------------------------------- 6 1,-2 ----GAGGUAGUAGGUUGUAUAGU-------------------------------------------------- 7044 1,-1 ----GAGGUAGUAGGUUGUAUAGUa------------------------------------------------- 254 1,-1 ----GAGGUAGUAGGUUGUAUAGUaa------------------------------------------------ 67 1,-1 ----GAGGUAGUAGGUUGUAUAGUau------------------------------------------------ 6 1,-1 ----GAGGUAGUAGGUUGUAUAGUc------------------------------------------------- 12 1,-1 ----GAGGUAGUAGGUUGUAUAGUg------------------------------------------------- 2 1,-1 ----GAGGUAGUAGGUUGUAUAGUU------------------------------------------------- 21516 1,0 ----GAGGUAGUAGGUUGUAUAGUUa------------------------------------------------ 1086 1,0 ----GAGGUAGUAGGUUGUAUAGUUaa----------------------------------------------- 18 1,0 ----GAGGUAGUAGGUUGUAUAGUUau----------------------------------------------- 12 1,0 ----GAGGUAGUAGGUUGUAUAGUUc------------------------------------------------ 4 1,0 ----GAGGUAGUAGGUUGUAUAGUUg------------------------------------------------ 40 1,0 ----GAGGUAGUAGGUUGUAUAGUUU------------------------------------------------ 1136 1,1 -----AGGUAGUAGGUUGUAUAG--------------------------------------------------- 12 2,-2 -----AGGUAGUAGGUUGUAUAGU-------------------------------------------------- 196 2,-1 -----AGGUAGUAGGUUGUAUAGUa------------------------------------------------- 5 2,-1 -----AGGUAGUAGGUUGUAUAGUU------------------------------------------------- 770 2,0 -----AGGUAGUAGGUUGUAUAGUUa------------------------------------------------ 29 2,0 -----AGGUAGUAGGUUGUAUAGUUU------------------------------------------------ 38 2,1 ---------------------------------------------------CUAUACAAUCUACUGUCUU---- 11 0,-2 ---------------------------------------------------CUAUACAAUCUACUGUCUUau-- 2 0,-2 ---------------------------------------------------CUAUACAAUCUACUGUCUUU--- 841 0,-1 ---------------------------------------------------CUAUACAAUCUACUGUCUUUa-- 2 0,-1 ---------------------------------------------------CUAUACAAUCUACUGUCUUUau- 2 0,-1 ---------------------------------------------------CUAUACAAUCUACUGUCUUUu-- 35 0,-1 ---------------------------------------------------CUAUACAAUCUACUGUCUUUuu- 28 0,-1 ---------------------------------------------------CUAUACAAUCUACUGUCUUUC-- 1236 0,0 ---------------------------------------------------CUAUACAAUCUACUGUCUUUCa- 49 0,0 ---------------------------------------------------CUAUACAAUCUACUGUCUUUCu- 2077 0,0 ---------------------------------------------------CUAUACAAUCUACUGUCUUUCuu 2 0,0 ---------------------------------------------------CUAUACAAUCUACUGUCUUUCC- 772 0,1 ---------------------------------------------------CUAUACAAUCUACUGUCUUUCCa 35 0,1 ---------------------------------------------------CUAUACAAUCUACUGUCUUUCCU 5 0,2 ----------------------------------------------------UAUACAAUCUACUGUCUUU--- 22 1,-1 ----------------------------------------------------UAUACAAUCUACUGUCUUUC-- 38 1,0 ----------------------------------------------------UAUACAAUCUACUGUCUUUCu- 46 1,0 ----------------------------------------------------UAUACAAUCUACUGUCUUUCC- 36 1,1 ----------------------------------------------------UAUACAAUCUACUGUCUUUCCa 2 1,1 ----------------------------------------------------UAUACAAUCUACUGUCUUUCCU 54 1,2 ----------------------------------------------------UAUACAAUCUACUGUCUUUCCUu 2 1,2 -----------------------------------------------------AUACAAUCUACUGUCUUUC-- 6 2,0 -----------------------------------------------------AUACAAUCUACUGUCUUUCu- 2 2,0 -----------------------------------------------------AUACAAUCUACUGUCUUUCC- 4 2,1 -----------------------------------------------------AUACAAUCUACUGUCUUUCCU 13 2,2 >hsa-let-7b MA:6-27;mi:60-81 Tumor cggggUGAGGUAGUAGGUUGUGUGGUUucagggcagugauguugccccucggaagauaaCUAUACAACCUACUGCCUUCCCug ----GUGAGGUAGUAGGUUGUGU------------------------------------------------------------ 2 -1,-4 ----GUGAGGUAGUAGGUUGUGUGGUUaa------------------------------------------------------ 2 -1,0 -----UGAGGUAGUAGGUUGUGU------------------------------------------------------------ 6226 0,-4 -----UGAGGUAGUAGGUUGUGUa----------------------------------------------------------- 89 0,-4 -----UGAGGUAGUAGGUUGUGUaa---------------------------------------------------------- 323 0,-4 -----UGAGGUAGUAGGUUGUGUau---------------------------------------------------------- 26 0,-4 -----UGAGGUAGUAGGUUGUGUu----------------------------------------------------------- 46 0,-4 -----UGAGGUAGUAGGUUGUGUuu---------------------------------------------------------- 11 0,-4 -----UGAGGUAGUAGGUUGUGUG----------------------------------------------------------- 4354 0,-3 -----UGAGGUAGUAGGUUGUGUGa---------------------------------------------------------- 3255 0,-3 -----UGAGGUAGUAGGUUGUGUGaa--------------------------------------------------------- 496 0,-3 -----UGAGGUAGUAGGUUGUGUGau--------------------------------------------------------- 245 0,-3 -----UGAGGUAGUAGGUUGUGUGc---------------------------------------------------------- 8 0,-3 -----UGAGGUAGUAGGUUGUGUGu---------------------------------------------------------- 1358 0,-3 -----UGAGGUAGUAGGUUGUGUGuu--------------------------------------------------------- 249 0,-3 -----UGAGGUAGUAGGUUGUGUGG---------------------------------------------------------- 23729 0,-2 -----UGAGGUAGUAGGUUGUGUGGa--------------------------------------------------------- 1587 0,-2 -----UGAGGUAGUAGGUUGUGUGGaa-------------------------------------------------------- 1070 0,-2 -----UGAGGUAGUAGGUUGUGUGGau-------------------------------------------------------- 195 0,-2 -----UGAGGUAGUAGGUUGUGUGGc--------------------------------------------------------- 107 0,-2 -----UGAGGUAGUAGGUUGUGUGGg--------------------------------------------------------- 28 0,-2 -----UGAGGUAGUAGGUUGUGUGGU--------------------------------------------------------- 81968 0,-1 -----UGAGGUAGUAGGUUGUGUGGUa-------------------------------------------------------- 8671 0,-1 -----UGAGGUAGUAGGUUGUGUGGUaa------------------------------------------------------- 6964 0,-1 -----UGAGGUAGUAGGUUGUGUGGUau------------------------------------------------------- 7723 0,-1 -----UGAGGUAGUAGGUUGUGUGGUc-------------------------------------------------------- 430 0,-1 -----UGAGGUAGUAGGUUGUGUGGUg-------------------------------------------------------- 211 0,-1 -----UGAGGUAGUAGGUUGUGUGGUU-------------------------------------------------------- 286043 0,0 -----UGAGGUAGUAGGUUGUGUGGUUa------------------------------------------------------- 26331 0,0 -----UGAGGUAGUAGGUUGUGUGGUUaa------------------------------------------------------ 4344 0,0 -----UGAGGUAGUAGGUUGUGUGGUUau------------------------------------------------------ 8594 0,0 -----UGAGGUAGUAGGUUGUGUGGUUc------------------------------------------------------- 577 0,0 -----UGAGGUAGUAGGUUGUGUGGUUg------------------------------------------------------- 1300 0,0 -----UGAGGUAGUAGGUUGUGUGGUUU------------------------------------------------------- 108570 0,1 -----UGAGGUAGUAGGUUGUGUGGUUUa------------------------------------------------------ 1721 0,1 -----UGAGGUAGUAGGUUGUGUGGUUUaa----------------------------------------------------- 188 0,1 -----UGAGGUAGUAGGUUGUGUGGUUUau----------------------------------------------------- 354 0,1 -----UGAGGUAGUAGGUUGUGUGGUUUg------------------------------------------------------ 74 0,1 -----UGAGGUAGUAGGUUGUGUGGUUUu------------------------------------------------------ 12513 0,1 -----UGAGGUAGUAGGUUGUGUGGUUUuu----------------------------------------------------- 1078 0,1 -----UGAGGUAGUAGGUUGUGUGGUUUC------------------------------------------------------ 109 0,2 ------GAGGUAGUAGGUUGUGUG----------------------------------------------------------- 52 1,-3 ------GAGGUAGUAGGUUGUGUGa---------------------------------------------------------- 53 1,-3 ------GAGGUAGUAGGUUGUGUGaa--------------------------------------------------------- 2 1,-3 ------GAGGUAGUAGGUUGUGUGau--------------------------------------------------------- 2 1,-3 ------GAGGUAGUAGGUUGUGUGu---------------------------------------------------------- 22 1,-3 ------GAGGUAGUAGGUUGUGUGG---------------------------------------------------------- 535 1,-2 ------GAGGUAGUAGGUUGUGUGGa--------------------------------------------------------- 27 1,-2 ------GAGGUAGUAGGUUGUGUGGaa-------------------------------------------------------- 27 1,-2 ------GAGGUAGUAGGUUGUGUGGU--------------------------------------------------------- 2172 1,-1 ------GAGGUAGUAGGUUGUGUGGUa-------------------------------------------------------- 287 1,-1 ------GAGGUAGUAGGUUGUGUGGUaa------------------------------------------------------- 142 1,-1 ------GAGGUAGUAGGUUGUGUGGUau------------------------------------------------------- 220 1,-1 ------GAGGUAGUAGGUUGUGUGGUc-------------------------------------------------------- 4 1,-1 ------GAGGUAGUAGGUUGUGUGGUg-------------------------------------------------------- 6 1,-1 ------GAGGUAGUAGGUUGUGUGGUU-------------------------------------------------------- 7892 1,0 ------GAGGUAGUAGGUUGUGUGGUUa------------------------------------------------------- 685 1,0 ------GAGGUAGUAGGUUGUGUGGUUaa------------------------------------------------------ 97 1,0 ------GAGGUAGUAGGUUGUGUGGUUau------------------------------------------------------ 239 1,0 ------GAGGUAGUAGGUUGUGUGGUUc------------------------------------------------------- 4 1,0 ------GAGGUAGUAGGUUGUGUGGUUg------------------------------------------------------- 27 1,0 ------GAGGUAGUAGGUUGUGUGGUUU------------------------------------------------------- 3066 1,1 ------GAGGUAGUAGGUUGUGUGGUUUa------------------------------------------------------ 40 1,1 ------GAGGUAGUAGGUUGUGUGGUUUu------------------------------------------------------ 364 1,1 ------GAGGUAGUAGGUUGUGUGGUUUuu----------------------------------------------------- 12 1,1 ------GAGGUAGUAGGUUGUGUGGUUUC------------------------------------------------------ 3 1,2 -------AGGUAGUAGGUUGUGUGG---------------------------------------------------------- 9 2,-2 -------AGGUAGUAGGUUGUGUGGU--------------------------------------------------------- 46 2,-1 -------AGGUAGUAGGUUGUGUGGUU-------------------------------------------------------- 216 2,0 -------AGGUAGUAGGUUGUGUGGUUa------------------------------------------------------- 2 2,0 -------AGGUAGUAGGUUGUGUGGUUU------------------------------------------------------- 65 2,1 -----------------------------------------------------------CUAUACAACCUACUGCCUU----- 4 0,-3 -----------------------------------------------------------CUAUACAACCUACUGCCUUu---- 4 0,-3 -----------------------------------------------------------CUAUACAACCUACUGCCUUC---- 390 0,-2 -----------------------------------------------------------CUAUACAACCUACUGCCUUCau-- 2 0,-2 -----------------------------------------------------------CUAUACAACCUACUGCCUUCu--- 220 0,-2 -----------------------------------------------------------CUAUACAACCUACUGCCUUCuu-- 69 0,-2 -----------------------------------------------------------CUAUACAACCUACUGCCUUCC--- 687 0,-1 -----------------------------------------------------------CUAUACAACCUACUGCCUUCCa-- 32 0,-1 -----------------------------------------------------------CUAUACAACCUACUGCCUUCCu-- 850 0,-1 -----------------------------------------------------------CUAUACAACCUACUGCCUUCCuu- 3 0,-1 ------------------------------------------------------------UAUACAACCUACUGCCUUC---- 5 1,-2 ------------------------------------------------------------UAUACAACCUACUGCCUUCu--- 2 1,-2 ------------------------------------------------------------UAUACAACCUACUGCCUUCC--- 10 1,-1 ------------------------------------------------------------UAUACAACCUACUGCCUUCCu-- 7 1,-1 >hsa-let-7c 5pM:11-32 Tumor gcauccggguUGAGGUAGUAGGUUGUAUGGUUuagaguuacacccugggaguuaacuguacaaccuucuagcuuuccuuggagc --------GUUGAGGUAGUAGGUUGUAUGGU----------------------------------------------------- 9 -2,-1 ---------UUGAGGUAGUAGGUUGUAUGG------------------------------------------------------ 10 -1,-2 ---------UUGAGGUAGUAGGUUGUAUGGU----------------------------------------------------- 164 -1,-1 ---------UUGAGGUAGUAGGUUGUAUGGUa---------------------------------------------------- 10 -1,-1 ---------UUGAGGUAGUAGGUUGUAUGGUU---------------------------------------------------- 171 -1,0 ---------UUGAGGUAGUAGGUUGUAUGGUUU--------------------------------------------------- 6 -1,1 ----------UGAGGUAGUAGGUUGUAU-------------------------------------------------------- 9800 0,-4 ----------UGAGGUAGUAGGUUGUAUu------------------------------------------------------- 161 0,-4 ----------UGAGGUAGUAGGUUGUAUuu------------------------------------------------------ 40 0,-4 ----------UGAGGUAGUAGGUUGUAUG------------------------------------------------------- 410 0,-3 ----------UGAGGUAGUAGGUUGUAUGa------------------------------------------------------ 124 0,-3 ----------UGAGGUAGUAGGUUGUAUGaa----------------------------------------------------- 8 0,-3 ----------UGAGGUAGUAGGUUGUAUGau----------------------------------------------------- 6 0,-3 ----------UGAGGUAGUAGGUUGUAUGu------------------------------------------------------ 30 0,-3 ----------UGAGGUAGUAGGUUGUAUGuu----------------------------------------------------- 21 0,-3 ----------UGAGGUAGUAGGUUGUAUGG------------------------------------------------------ 1355 0,-2 ----------UGAGGUAGUAGGUUGUAUGGa----------------------------------------------------- 195 0,-2 ----------UGAGGUAGUAGGUUGUAUGGaa---------------------------------------------------- 93 0,-2 ----------UGAGGUAGUAGGUUGUAUGGau---------------------------------------------------- 8 0,-2 ----------UGAGGUAGUAGGUUGUAUGGc----------------------------------------------------- 8 0,-2 ----------UGAGGUAGUAGGUUGUAUGGg----------------------------------------------------- 4 0,-2 ----------UGAGGUAGUAGGUUGUAUGGU----------------------------------------------------- 9866 0,-1 ----------UGAGGUAGUAGGUUGUAUGGUa---------------------------------------------------- 1837 0,-1 ----------UGAGGUAGUAGGUUGUAUGGUaa--------------------------------------------------- 672 0,-1 ----------UGAGGUAGUAGGUUGUAUGGUau--------------------------------------------------- 330 0,-1 ----------UGAGGUAGUAGGUUGUAUGGUc---------------------------------------------------- 46 0,-1 ----------UGAGGUAGUAGGUUGUAUGGUg---------------------------------------------------- 23 0,-1 ----------UGAGGUAGUAGGUUGUAUGGUU---------------------------------------------------- 57475 0,0 ----------UGAGGUAGUAGGUUGUAUGGUUa--------------------------------------------------- 3276 0,0 ----------UGAGGUAGUAGGUUGUAUGGUUaa-------------------------------------------------- 172 0,0 ----------UGAGGUAGUAGGUUGUAUGGUUau-------------------------------------------------- 200 0,0 ----------UGAGGUAGUAGGUUGUAUGGUUc--------------------------------------------------- 26 0,0 ----------UGAGGUAGUAGGUUGUAUGGUUg--------------------------------------------------- 207 0,0 ----------UGAGGUAGUAGGUUGUAUGGUUU--------------------------------------------------- 4396 0,1 ----------UGAGGUAGUAGGUUGUAUGGUUUu-------------------------------------------------- 142 0,1 ----------UGAGGUAGUAGGUUGUAUGGUUUuu------------------------------------------------- 2 0,1 ----------UGAGGUAGUAGGUUGUAUGGUUUA-------------------------------------------------- 15 0,2 -----------GAGGUAGUAGGUUGUAUGG------------------------------------------------------ 18 1,-2 -----------GAGGUAGUAGGUUGUAUGGU----------------------------------------------------- 262 1,-1 -----------GAGGUAGUAGGUUGUAUGGUa---------------------------------------------------- 30 1,-1 -----------GAGGUAGUAGGUUGUAUGGUaa--------------------------------------------------- 4 1,-1 -----------GAGGUAGUAGGUUGUAUGGUU---------------------------------------------------- 1671 1,0 -----------GAGGUAGUAGGUUGUAUGGUUa--------------------------------------------------- 81 1,0 -----------GAGGUAGUAGGUUGUAUGGUUaa-------------------------------------------------- 2 1,0 -----------GAGGUAGUAGGUUGUAUGGUUU--------------------------------------------------- 85 1,1 ------------AGGUAGUAGGUUGUAUGGU----------------------------------------------------- 4 2,-1 ------------AGGUAGUAGGUUGUAUGGUU---------------------------------------------------- 42 2,0 -------------------------------------------------------CUGUACAACCUUCUAGCUUUC-------- 6 -------------------------------------------------------CUGUACAACCUUCUAGCUUUCu------- 2 -------------------------------------------------------CUGUACAACCUUCUAGCUUUCC------- 23 >hsa-let-7d MA:8-29;mi:62-83 Tumor ccuaggaAGAGGUAGUAGGUUGCAUAGUUuuagggcagggauuuugcccacaaggagguaaCUAUACGACCUGCUGCCUUUCUuagg ------AAGAGGUAGUAGGUUGCAUAGU----------------------------------------------------------- 41 -1,-1 ------AAGAGGUAGUAGGUUGCAUAGUU---------------------------------------------------------- 19 -1,0 -------AGAGGUAGUAGGUUGCAU-------------------------------------------------------------- 977 0,-4 -------AGAGGUAGUAGGUUGCAUu------------------------------------------------------------- 14 0,-4 -------AGAGGUAGUAGGUUGCAUuu------------------------------------------------------------ 4 0,-4 -------AGAGGUAGUAGGUUGCAUA------------------------------------------------------------- 618 0,-3 -------AGAGGUAGUAGGUUGCAUAa------------------------------------------------------------ 132 0,-3 -------AGAGGUAGUAGGUUGCAUAaa----------------------------------------------------------- 26 0,-3 -------AGAGGUAGUAGGUUGCAUAau----------------------------------------------------------- 53 0,-3 -------AGAGGUAGUAGGUUGCAUAu------------------------------------------------------------ 28 0,-3 -------AGAGGUAGUAGGUUGCAUAuu----------------------------------------------------------- 52 0,-3 -------AGAGGUAGUAGGUUGCAUAG------------------------------------------------------------ 5912 0,-2 -------AGAGGUAGUAGGUUGCAUAGa----------------------------------------------------------- 1317 0,-2 -------AGAGGUAGUAGGUUGCAUAGaa---------------------------------------------------------- 182 0,-2 -------AGAGGUAGUAGGUUGCAUAGau---------------------------------------------------------- 44 0,-2 -------AGAGGUAGUAGGUUGCAUAGc----------------------------------------------------------- 23 0,-2 -------AGAGGUAGUAGGUUGCAUAGg----------------------------------------------------------- 22 0,-2 -------AGAGGUAGUAGGUUGCAUAGU----------------------------------------------------------- 31650 0,-1 -------AGAGGUAGUAGGUUGCAUAGUa---------------------------------------------------------- 1227 0,-1 -------AGAGGUAGUAGGUUGCAUAGUaa--------------------------------------------------------- 559 0,-1 -------AGAGGUAGUAGGUUGCAUAGUau--------------------------------------------------------- 214 0,-1 -------AGAGGUAGUAGGUUGCAUAGUc---------------------------------------------------------- 121 0,-1 -------AGAGGUAGUAGGUUGCAUAGUg---------------------------------------------------------- 19 0,-1 -------AGAGGUAGUAGGUUGCAUAGUU---------------------------------------------------------- 87758 0,0 -------AGAGGUAGUAGGUUGCAUAGUUa--------------------------------------------------------- 4827 0,0 -------AGAGGUAGUAGGUUGCAUAGUUaa-------------------------------------------------------- 362 0,0 -------AGAGGUAGUAGGUUGCAUAGUUau-------------------------------------------------------- 218 0,0 -------AGAGGUAGUAGGUUGCAUAGUUc--------------------------------------------------------- 23 0,0 -------AGAGGUAGUAGGUUGCAUAGUUg--------------------------------------------------------- 329 0,0 -------AGAGGUAGUAGGUUGCAUAGUUU--------------------------------------------------------- 8319 0,1 -------AGAGGUAGUAGGUUGCAUAGUUUa-------------------------------------------------------- 35 0,1 -------AGAGGUAGUAGGUUGCAUAGUUUU-------------------------------------------------------- 185 0,2 --------GAGGUAGUAGGUUGCAUA------------------------------------------------------------- 4 1,-3 --------GAGGUAGUAGGUUGCAUAG------------------------------------------------------------ 103 1,-2 --------GAGGUAGUAGGUUGCAUAGa----------------------------------------------------------- 21 1,-2 --------GAGGUAGUAGGUUGCAUAGU----------------------------------------------------------- 872 1,-1 --------GAGGUAGUAGGUUGCAUAGUa---------------------------------------------------------- 8 1,-1 --------GAGGUAGUAGGUUGCAUAGUaa--------------------------------------------------------- 9 1,-1 --------GAGGUAGUAGGUUGCAUAGUU---------------------------------------------------------- 2362 1,0 --------GAGGUAGUAGGUUGCAUAGUUa--------------------------------------------------------- 104 1,0 --------GAGGUAGUAGGUUGCAUAGUUg--------------------------------------------------------- 2 1,0 --------GAGGUAGUAGGUUGCAUAGUUU--------------------------------------------------------- 189 1,1 ---------AGGUAGUAGGUUGCAUAGU----------------------------------------------------------- 13 2,-1 ---------AGGUAGUAGGUUGCAUAGUU---------------------------------------------------------- 82 2,0 -------------------------------------------------------------CUAUACGACCUGCUGCCU-------- 2 0,-4 -------------------------------------------------------------CUAUACGACCUGCUGCCUU------- 13 0,-3 -------------------------------------------------------------CUAUACGACCUGCUGCCUUU------ 527 0,-2 -------------------------------------------------------------CUAUACGACCUGCUGCCUUUa----- 5 0,-2 -------------------------------------------------------------CUAUACGACCUGCUGCCUUUu----- 27 0,-2 -------------------------------------------------------------CUAUACGACCUGCUGCCUUUuu---- 5 0,-2 -------------------------------------------------------------CUAUACGACCUGCUGCCUUUC----- 730 0,-1 -------------------------------------------------------------CUAUACGACCUGCUGCCUUUCa---- 58 0,-1 -------------------------------------------------------------CUAUACGACCUGCUGCCUUUCc---- 16 0,-1 -------------------------------------------------------------CUAUACGACCUGCUGCCUUUCU---- 2088 0,0 --------------------------------------------------------------UAUACGACCUGCUGCCUUU------ 15 1,-2 --------------------------------------------------------------UAUACGACCUGCUGCCUUUC----- 35 1,-1 --------------------------------------------------------------UAUACGACCUGCUGCCUUUCU---- 139 1,0 >hsa-let-7e MA:8-29;mi:53-74 Tumor cccgggcUGAGGUAGGAGGUUGUAUAGUUgaggaggacacccaaggagaucaCUAUACGGCCUCCUAGCUUUCCccagg ------CUGAGGUAGGAGGUUGUAUAGU--------------------------------------------------- 37 -1,-1 ------CUGAGGUAGGAGGUUGUAUAGUa-------------------------------------------------- 2 -1,-1 ------CUGAGGUAGGAGGUUGUAUAGUU-------------------------------------------------- 136 -1,0 ------CUGAGGUAGGAGGUUGUAUAGUUa------------------------------------------------- 4 -1,0 ------CUGAGGUAGGAGGUUGUAUAGUUu------------------------------------------------- 9 -1,0 ------CUGAGGUAGGAGGUUGUAUAGUUG------------------------------------------------- 2 -1,1 -------UGAGGUAGGAGGUUGUAU------------------------------------------------------ 549 0,-4 -------UGAGGUAGGAGGUUGUAUu----------------------------------------------------- 4 0,-4 -------UGAGGUAGGAGGUUGUAUA----------------------------------------------------- 291 0,-3 -------UGAGGUAGGAGGUUGUAUAa---------------------------------------------------- 120 0,-3 -------UGAGGUAGGAGGUUGUAUAaa--------------------------------------------------- 64 0,-3 -------UGAGGUAGGAGGUUGUAUAau--------------------------------------------------- 31 0,-3 -------UGAGGUAGGAGGUUGUAUAu---------------------------------------------------- 28 0,-3 -------UGAGGUAGGAGGUUGUAUAuu--------------------------------------------------- 14 0,-3 -------UGAGGUAGGAGGUUGUAUAG---------------------------------------------------- 2702 0,-2 -------UGAGGUAGGAGGUUGUAUAGa--------------------------------------------------- 1041 0,-2 -------UGAGGUAGGAGGUUGUAUAGaa-------------------------------------------------- 364 0,-2 -------UGAGGUAGGAGGUUGUAUAGau-------------------------------------------------- 33 0,-2 -------UGAGGUAGGAGGUUGUAUAGc--------------------------------------------------- 16 0,-2 -------UGAGGUAGGAGGUUGUAUAGg--------------------------------------------------- 2 0,-2 -------UGAGGUAGGAGGUUGUAUAGU--------------------------------------------------- 17929 0,-1 -------UGAGGUAGGAGGUUGUAUAGUa-------------------------------------------------- 945 0,-1 -------UGAGGUAGGAGGUUGUAUAGUaa------------------------------------------------- 730 0,-1 -------UGAGGUAGGAGGUUGUAUAGUau------------------------------------------------- 353 0,-1 -------UGAGGUAGGAGGUUGUAUAGUc-------------------------------------------------- 36 0,-1 -------UGAGGUAGGAGGUUGUAUAGUg-------------------------------------------------- 19 0,-1 -------UGAGGUAGGAGGUUGUAUAGUU-------------------------------------------------- 40937 0,0 -------UGAGGUAGGAGGUUGUAUAGUUa------------------------------------------------- 3186 0,0 -------UGAGGUAGGAGGUUGUAUAGUUaa------------------------------------------------ 273 0,0 -------UGAGGUAGGAGGUUGUAUAGUUau------------------------------------------------ 191 0,0 -------UGAGGUAGGAGGUUGUAUAGUUc------------------------------------------------- 8 0,0 -------UGAGGUAGGAGGUUGUAUAGUUu------------------------------------------------- 4911 0,0 -------UGAGGUAGGAGGUUGUAUAGUUuu------------------------------------------------ 167 0,0 -------UGAGGUAGGAGGUUGUAUAGUUG------------------------------------------------- 1181 0,1 -------UGAGGUAGGAGGUUGUAUAGUUGu------------------------------------------------ 205 0,1 -------UGAGGUAGGAGGUUGUAUAGUUGA------------------------------------------------ 178 0,2 --------GAGGUAGGAGGUUGUAUAG---------------------------------------------------- 12 1,-2 --------GAGGUAGGAGGUUGUAUAGa--------------------------------------------------- 8 1,-2 --------GAGGUAGGAGGUUGUAUAGU--------------------------------------------------- 335 1,-1 --------GAGGUAGGAGGUUGUAUAGUa-------------------------------------------------- 7 1,-1 --------GAGGUAGGAGGUUGUAUAGUaa------------------------------------------------- 2 1,-1 --------GAGGUAGGAGGUUGUAUAGUau------------------------------------------------- 2 1,-1 --------GAGGUAGGAGGUUGUAUAGUU-------------------------------------------------- 846 1,0 --------GAGGUAGGAGGUUGUAUAGUUa------------------------------------------------- 39 1,0 --------GAGGUAGGAGGUUGUAUAGUUaa------------------------------------------------ 2 1,0 --------GAGGUAGGAGGUUGUAUAGUUu------------------------------------------------- 73 1,0 --------GAGGUAGGAGGUUGUAUAGUUG------------------------------------------------- 15 1,1 ---------AGGUAGGAGGUUGUAUAGU--------------------------------------------------- 2 2,-1 ---------AGGUAGGAGGUUGUAUAGUU-------------------------------------------------- 21 2,0 ---------AGGUAGGAGGUUGUAUAGUUu------------------------------------------------- 2 2,0 ---------------------------------------------------ACUAUACGGCCUCCUAGCUUU------- 2 -1,-2 ----------------------------------------------------CUAUACGGCCUCCUAGCUU-------- 2 0,-3 ----------------------------------------------------CUAUACGGCCUCCUAGCUUU------- 63 0,-2 ----------------------------------------------------CUAUACGGCCUCCUAGCUUUa------ 2 0,-2 ----------------------------------------------------CUAUACGGCCUCCUAGCUUUu------ 2 0,-2 ----------------------------------------------------CUAUACGGCCUCCUAGCUUUC------ 102 0,-1 ----------------------------------------------------CUAUACGGCCUCCUAGCUUUCa----- 2 0,-1 ----------------------------------------------------CUAUACGGCCUCCUAGCUUUCu----- 34 0,-1 ----------------------------------------------------CUAUACGGCCUCCUAGCUUUCC----- 94 0,0 ----------------------------------------------------CUAUACGGCCUCCUAGCUUUCCa---- 2 0,0 ----------------------------------------------------CUAUACGGCCUCCUAGCUUUCCu---- 2 0,0 >hsa-let-7f-1 MA:7-28;mi:63-84 Tumor ucagagUGAGGUAGUAGAUUGUAUAGUUgugggguagugauuuuacccuguucaggagauaaCUAUACAAUCUAUUGCCUUCCCuga -----GUGAGGUAGUAGAUUGUAUAGU------------------------------------------------------------ 5 -1,-1 ------UGAGGUAGUAGAUUGUAU--------------------------------------------------------------- 7829 0,-4 ------UGAGGUAGUAGAUUGUAUu-------------------------------------------------------------- 17 0,-4 ------UGAGGUAGUAGAUUGUAUuu------------------------------------------------------------- 10 0,-4 ------UGAGGUAGUAGAUUGUAUA-------------------------------------------------------------- 6084 0,-3 ------UGAGGUAGUAGAUUGUAUAa------------------------------------------------------------- 1167 0,-3 ------UGAGGUAGUAGAUUGUAUAaa------------------------------------------------------------ 201 0,-3 ------UGAGGUAGUAGAUUGUAUAau------------------------------------------------------------ 342 0,-3 ------UGAGGUAGUAGAUUGUAUAu------------------------------------------------------------- 171 0,-3 ------UGAGGUAGUAGAUUGUAUAuu------------------------------------------------------------ 477 0,-3 ------UGAGGUAGUAGAUUGUAUAG------------------------------------------------------------- 32642 0,-2 ------UGAGGUAGUAGAUUGUAUAGa------------------------------------------------------------ 2734 0,-2 ------UGAGGUAGUAGAUUGUAUAGaa----------------------------------------------------------- 366 0,-2 ------UGAGGUAGUAGAUUGUAUAGau----------------------------------------------------------- 222 0,-2 ------UGAGGUAGUAGAUUGUAUAGc------------------------------------------------------------ 273 0,-2 ------UGAGGUAGUAGAUUGUAUAGg------------------------------------------------------------ 247 0,-2 ------UGAGGUAGUAGAUUGUAUAGU------------------------------------------------------------ 183007 0,-1 ------UGAGGUAGUAGAUUGUAUAGUa----------------------------------------------------------- 5655 0,-1 ------UGAGGUAGUAGAUUGUAUAGUaa---------------------------------------------------------- 2687 0,-1 ------UGAGGUAGUAGAUUGUAUAGUau---------------------------------------------------------- 333 0,-1 ------UGAGGUAGUAGAUUGUAUAGUc----------------------------------------------------------- 928 0,-1 ------UGAGGUAGUAGAUUGUAUAGUg----------------------------------------------------------- 287 0,-1 ------UGAGGUAGUAGAUUGUAUAGUU----------------------------------------------------------- 676789 0,0 ------UGAGGUAGUAGAUUGUAUAGUUa---------------------------------------------------------- 32660 0,0 ------UGAGGUAGUAGAUUGUAUAGUUaa--------------------------------------------------------- 1285 0,0 ------UGAGGUAGUAGAUUGUAUAGUUau--------------------------------------------------------- 376 0,0 ------UGAGGUAGUAGAUUGUAUAGUUc---------------------------------------------------------- 210 0,0 ------UGAGGUAGUAGAUUGUAUAGUUG---------------------------------------------------------- 2653 0,1 ------UGAGGUAGUAGAUUGUAUAGUUGa--------------------------------------------------------- 78 0,1 ------UGAGGUAGUAGAUUGUAUAGUUGU--------------------------------------------------------- 100 0,2 ------UGAGGUAGUAGAUUGUAUAGUUGUG-------------------------------------------------------- 5 0,3 -------GAGGUAGUAGAUUGUAUA-------------------------------------------------------------- 87 1,-3 -------GAGGUAGUAGAUUGUAUAa------------------------------------------------------------- 17 1,-3 -------GAGGUAGUAGAUUGUAUAau------------------------------------------------------------ 2 1,-3 -------GAGGUAGUAGAUUGUAUAG------------------------------------------------------------- 769 1,-2 -------GAGGUAGUAGAUUGUAUAGa------------------------------------------------------------ 48 1,-2 -------GAGGUAGUAGAUUGUAUAGau----------------------------------------------------------- 2 1,-2 -------GAGGUAGUAGAUUGUAUAGc------------------------------------------------------------ 2 1,-2 -------GAGGUAGUAGAUUGUAUAGU------------------------------------------------------------ 5346 1,-1 -------GAGGUAGUAGAUUGUAUAGUa----------------------------------------------------------- 138 1,-1 -------GAGGUAGUAGAUUGUAUAGUaa---------------------------------------------------------- 48 1,-1 -------GAGGUAGUAGAUUGUAUAGUau---------------------------------------------------------- 2 1,-1 -------GAGGUAGUAGAUUGUAUAGUc----------------------------------------------------------- 10 1,-1 -------GAGGUAGUAGAUUGUAUAGUU----------------------------------------------------------- 19771 1,0 -------GAGGUAGUAGAUUGUAUAGUUa---------------------------------------------------------- 987 1,0 -------GAGGUAGUAGAUUGUAUAGUUaa--------------------------------------------------------- 13 1,0 -------GAGGUAGUAGAUUGUAUAGUUc---------------------------------------------------------- 6 1,0 -------GAGGUAGUAGAUUGUAUAGUUG---------------------------------------------------------- 54 1,1 --------AGGUAGUAGAUUGUAUAG------------------------------------------------------------- 2 2,-2 --------AGGUAGUAGAUUGUAUAGU------------------------------------------------------------ 76 2,-1 --------AGGUAGUAGAUUGUAUAGUa----------------------------------------------------------- 2 2,-1 --------AGGUAGUAGAUUGUAUAGUU----------------------------------------------------------- 404 2,0 --------AGGUAGUAGAUUGUAUAGUUa---------------------------------------------------------- 12 2,0 --------AGGUAGUAGAUUGUAUAGUUG---------------------------------------------------------- 2 2,1 --------AGGUAGUAGAUUGUAUAGUUGU--------------------------------------------------------- 14 2,2 ------------------------------------------------------------AACUAUACAAUCUAUUGCCUUu----- 2 -2,-3 ------------------------------------------------------------AACUAUACAAUCUAUUGCCUUC----- 12 -2,-2 -------------------------------------------------------------ACUAUACAAUCUAUUGCCUUCC---- 2 -1,-1 --------------------------------------------------------------CUAUACAAUCUAUUGCCUUC----- 51 0,-2 --------------------------------------------------------------CUAUACAAUCUAUUGCCUUCu---- 36 0,-2 --------------------------------------------------------------CUAUACAAUCUAUUGCCUUCuu--- 2 0,-2 --------------------------------------------------------------CUAUACAAUCUAUUGCCUUCC---- 108 0,-1 --------------------------------------------------------------CUAUACAAUCUAUUGCCUUCCa--- 10 0,-1 --------------------------------------------------------------CUAUACAAUCUAUUGCCUUCCu--- 219 0,-1 --------------------------------------------------------------CUAUACAAUCUAUUGCCUUCCuu-- 6 0,-1 ---------------------------------------------------------------UAUACAAUCUAUUGCCUUC----- 2 1,-2 ---------------------------------------------------------------UAUACAAUCUAUUGCCUUCC---- 3 1,-1 ---------------------------------------------------------------UAUACAAUCUAUUGCCUUCCu--- 2 1,-1 >hsa-let-7f-2 MA:8-29;mi:58-79 Tumor ugugggaUGAGGUAGUAGAUUGUAUAGUUuuagggucauaccccaucuuggagauaaCUAUACAGUCUACUGUCUUUCCcacg ------AUGAGGUAGUAGAUUGUAUAG-------------------------------------------------------- 13 -1,-2 ------AUGAGGUAGUAGAUUGUAUAGU------------------------------------------------------- 144 -1,-1 ------AUGAGGUAGUAGAUUGUAUAGUU------------------------------------------------------ 270 -1,0 ------AUGAGGUAGUAGAUUGUAUAGUUU----------------------------------------------------- 4 -1,1 -------UGAGGUAGUAGAUUGUAU---------------------------------------------------------- 7829 0,-4 -------UGAGGUAGUAGAUUGUAUu--------------------------------------------------------- 17 0,-4 -------UGAGGUAGUAGAUUGUAUuu-------------------------------------------------------- 10 0,-4 -------UGAGGUAGUAGAUUGUAUA--------------------------------------------------------- 6084 0,-3 -------UGAGGUAGUAGAUUGUAUAa-------------------------------------------------------- 1167 0,-3 -------UGAGGUAGUAGAUUGUAUAaa------------------------------------------------------- 201 0,-3 -------UGAGGUAGUAGAUUGUAUAau------------------------------------------------------- 342 0,-3 -------UGAGGUAGUAGAUUGUAUAu-------------------------------------------------------- 171 0,-3 -------UGAGGUAGUAGAUUGUAUAuu------------------------------------------------------- 477 0,-3 -------UGAGGUAGUAGAUUGUAUAG-------------------------------------------------------- 32642 0,-2 -------UGAGGUAGUAGAUUGUAUAGa------------------------------------------------------- 2734 0,-2 -------UGAGGUAGUAGAUUGUAUAGaa------------------------------------------------------ 366 0,-2 -------UGAGGUAGUAGAUUGUAUAGau------------------------------------------------------ 222 0,-2 -------UGAGGUAGUAGAUUGUAUAGc------------------------------------------------------- 273 0,-2 -------UGAGGUAGUAGAUUGUAUAGg------------------------------------------------------- 247 0,-2 -------UGAGGUAGUAGAUUGUAUAGU------------------------------------------------------- 183007 0,-1 -------UGAGGUAGUAGAUUGUAUAGUa------------------------------------------------------ 5655 0,-1 -------UGAGGUAGUAGAUUGUAUAGUaa----------------------------------------------------- 2687 0,-1 -------UGAGGUAGUAGAUUGUAUAGUau----------------------------------------------------- 333 0,-1 -------UGAGGUAGUAGAUUGUAUAGUc------------------------------------------------------ 928 0,-1 -------UGAGGUAGUAGAUUGUAUAGUg------------------------------------------------------ 287 0,-1 -------UGAGGUAGUAGAUUGUAUAGUU------------------------------------------------------ 676789 0,0 -------UGAGGUAGUAGAUUGUAUAGUUa----------------------------------------------------- 32660 0,0 -------UGAGGUAGUAGAUUGUAUAGUUaa---------------------------------------------------- 1285 0,0 -------UGAGGUAGUAGAUUGUAUAGUUau---------------------------------------------------- 376 0,0 -------UGAGGUAGUAGAUUGUAUAGUUc----------------------------------------------------- 210 0,0 -------UGAGGUAGUAGAUUGUAUAGUUU----------------------------------------------------- 22655 0,1 -------UGAGGUAGUAGAUUGUAUAGUUUa---------------------------------------------------- 44 0,1 -------UGAGGUAGUAGAUUGUAUAGUUUc---------------------------------------------------- 4 0,1 -------UGAGGUAGUAGAUUGUAUAGUUUU---------------------------------------------------- 183 0,2 -------UGAGGUAGUAGAUUGUAUAGUUUUu--------------------------------------------------- 4 0,2 --------GAGGUAGUAGAUUGUAUA--------------------------------------------------------- 87 1,-3 --------GAGGUAGUAGAUUGUAUAa-------------------------------------------------------- 17 1,-3 --------GAGGUAGUAGAUUGUAUAau------------------------------------------------------- 2 1,-3 --------GAGGUAGUAGAUUGUAUAG-------------------------------------------------------- 769 1,-2 --------GAGGUAGUAGAUUGUAUAGa------------------------------------------------------- 48 1,-2 --------GAGGUAGUAGAUUGUAUAGau------------------------------------------------------ 2 1,-2 --------GAGGUAGUAGAUUGUAUAGc------------------------------------------------------- 2 1,-2 --------GAGGUAGUAGAUUGUAUAGU------------------------------------------------------- 5346 1,-1 --------GAGGUAGUAGAUUGUAUAGUa------------------------------------------------------ 138 1,-1 --------GAGGUAGUAGAUUGUAUAGUaa----------------------------------------------------- 48 1,-1 --------GAGGUAGUAGAUUGUAUAGUau----------------------------------------------------- 2 1,-1 --------GAGGUAGUAGAUUGUAUAGUc------------------------------------------------------ 10 1,-1 --------GAGGUAGUAGAUUGUAUAGUU------------------------------------------------------ 19771 1,0 --------GAGGUAGUAGAUUGUAUAGUUa----------------------------------------------------- 987 1,0 --------GAGGUAGUAGAUUGUAUAGUUaa---------------------------------------------------- 13 1,0 --------GAGGUAGUAGAUUGUAUAGUUc----------------------------------------------------- 6 1,0 --------GAGGUAGUAGAUUGUAUAGUUU----------------------------------------------------- 616 1,1 ---------AGGUAGUAGAUUGUAUAG-------------------------------------------------------- 2 2,-2 ---------AGGUAGUAGAUUGUAUAGU------------------------------------------------------- 76 2,-1 ---------AGGUAGUAGAUUGUAUAGUa------------------------------------------------------ 2 2,-1 ---------AGGUAGUAGAUUGUAUAGUU------------------------------------------------------ 404 2,0 ---------AGGUAGUAGAUUGUAUAGUUa----------------------------------------------------- 12 2,0 ---------AGGUAGUAGAUUGUAUAGUUU----------------------------------------------------- 6 2,1 ---------------------------------------------------------CUAUACAGUCUACUGUCUUU------ 41 0,-2 ---------------------------------------------------------CUAUACAGUCUACUGUCUUUuu---- 2 0,-2 ---------------------------------------------------------CUAUACAGUCUACUGUCUUUC----- 43 0,-1 ---------------------------------------------------------CUAUACAGUCUACUGUCUUUCu---- 249 0,-1 >hsa-let-7g MA:5-26;mi:62-82 Tumor aggcUGAGGUAGUAGUUUGUACAGUUugagggucuaugauaccacccgguacaggagauaaCUGUACAGGCCACUGCCUUGCca ---CUGAGGUAGUAGUUUGUA--------------------------------------------------------------- 2 -1,-5 ---CUGAGGUAGUAGUUUGUAC-------------------------------------------------------------- 8 -1,-4 ---CUGAGGUAGUAGUUUGUACA------------------------------------------------------------- 15 -1,-3 ---CUGAGGUAGUAGUUUGUACAG------------------------------------------------------------ 15 -1,-2 ---CUGAGGUAGUAGUUUGUACAGU----------------------------------------------------------- 439 -1,-1 ---CUGAGGUAGUAGUUUGUACAGUa---------------------------------------------------------- 2 -1,-1 ---CUGAGGUAGUAGUUUGUACAGUU---------------------------------------------------------- 1646 -1,0 ---CUGAGGUAGUAGUUUGUACAGUUa--------------------------------------------------------- 66 -1,0 ---CUGAGGUAGUAGUUUGUACAGUUg--------------------------------------------------------- 4 -1,0 ---CUGAGGUAGUAGUUUGUACAGUUU--------------------------------------------------------- 42 -1,1 ----UGAGGUAGUAGUUUGUAC-------------------------------------------------------------- 3997 0,-4 ----UGAGGUAGUAGUUUGUACc------------------------------------------------------------- 2 0,-4 ----UGAGGUAGUAGUUUGUACg------------------------------------------------------------- 2 0,-4 ----UGAGGUAGUAGUUUGUACu------------------------------------------------------------- 5 0,-4 ----UGAGGUAGUAGUUUGUACA------------------------------------------------------------- 2437 0,-3 ----UGAGGUAGUAGUUUGUACAa------------------------------------------------------------ 103 0,-3 ----UGAGGUAGUAGUUUGUACAaa----------------------------------------------------------- 2 0,-3 ----UGAGGUAGUAGUUUGUACAau----------------------------------------------------------- 44 0,-3 ----UGAGGUAGUAGUUUGUACAu------------------------------------------------------------ 2 0,-3 ----UGAGGUAGUAGUUUGUACAuu----------------------------------------------------------- 69 0,-3 ----UGAGGUAGUAGUUUGUACAG------------------------------------------------------------ 4912 0,-2 ----UGAGGUAGUAGUUUGUACAGa----------------------------------------------------------- 490 0,-2 ----UGAGGUAGUAGUUUGUACAGaa---------------------------------------------------------- 29 0,-2 ----UGAGGUAGUAGUUUGUACAGau---------------------------------------------------------- 36 0,-2 ----UGAGGUAGUAGUUUGUACAGc----------------------------------------------------------- 70 0,-2 ----UGAGGUAGUAGUUUGUACAGg----------------------------------------------------------- 51 0,-2 ----UGAGGUAGUAGUUUGUACAGU----------------------------------------------------------- 48210 0,-1 ----UGAGGUAGUAGUUUGUACAGUa---------------------------------------------------------- 1302 0,-1 ----UGAGGUAGUAGUUUGUACAGUaa--------------------------------------------------------- 425 0,-1 ----UGAGGUAGUAGUUUGUACAGUau--------------------------------------------------------- 98 0,-1 ----UGAGGUAGUAGUUUGUACAGUc---------------------------------------------------------- 258 0,-1 ----UGAGGUAGUAGUUUGUACAGUg---------------------------------------------------------- 45 0,-1 ----UGAGGUAGUAGUUUGUACAGUU---------------------------------------------------------- 192882 0,0 ----UGAGGUAGUAGUUUGUACAGUUa--------------------------------------------------------- 10711 0,0 ----UGAGGUAGUAGUUUGUACAGUUaa-------------------------------------------------------- 448 0,0 ----UGAGGUAGUAGUUUGUACAGUUau-------------------------------------------------------- 196 0,0 ----UGAGGUAGUAGUUUGUACAGUUc--------------------------------------------------------- 73 0,0 ----UGAGGUAGUAGUUUGUACAGUUg--------------------------------------------------------- 702 0,0 ----UGAGGUAGUAGUUUGUACAGUUU--------------------------------------------------------- 8115 0,1 ----UGAGGUAGUAGUUUGUACAGUUUa-------------------------------------------------------- 9 0,1 ----UGAGGUAGUAGUUUGUACAGUUUc-------------------------------------------------------- 2 0,1 ----UGAGGUAGUAGUUUGUACAGUUUu-------------------------------------------------------- 50 0,1 -----GAGGUAGUAGUUUGUACA------------------------------------------------------------- 35 1,-3 -----GAGGUAGUAGUUUGUACAG------------------------------------------------------------ 124 1,-2 -----GAGGUAGUAGUUUGUACAGa----------------------------------------------------------- 6 1,-2 -----GAGGUAGUAGUUUGUACAGU----------------------------------------------------------- 1866 1,-1 -----GAGGUAGUAGUUUGUACAGUa---------------------------------------------------------- 25 1,-1 -----GAGGUAGUAGUUUGUACAGUaa--------------------------------------------------------- 8 1,-1 -----GAGGUAGUAGUUUGUACAGUau--------------------------------------------------------- 2 1,-1 -----GAGGUAGUAGUUUGUACAGUc---------------------------------------------------------- 4 1,-1 -----GAGGUAGUAGUUUGUACAGUg---------------------------------------------------------- 2 1,-1 -----GAGGUAGUAGUUUGUACAGUU---------------------------------------------------------- 7706 1,0 -----GAGGUAGUAGUUUGUACAGUUa--------------------------------------------------------- 428 1,0 -----GAGGUAGUAGUUUGUACAGUUaa-------------------------------------------------------- 4 1,0 -----GAGGUAGUAGUUUGUACAGUUau-------------------------------------------------------- 2 1,0 -----GAGGUAGUAGUUUGUACAGUUg--------------------------------------------------------- 12 1,0 -----GAGGUAGUAGUUUGUACAGUUU--------------------------------------------------------- 290 1,1 -----GAGGUAGUAGUUUGUACAGUUUu-------------------------------------------------------- 2 1,1 ------AGGUAGUAGUUUGUACAGU----------------------------------------------------------- 15 2,-1 ------AGGUAGUAGUUUGUACAGUU---------------------------------------------------------- 81 2,0 ------------------------------------------------------------ACUGUACAGGCCACUGCCUUGC-- 4 -1,0 -------------------------------------------------------------CUGUACAGGCCACUGCCUUa--- 2 0,-2 -------------------------------------------------------------CUGUACAGGCCACUGCCUUG--- 111 0,-1 -------------------------------------------------------------CUGUACAGGCCACUGCCUUGa-- 15 0,-1 -------------------------------------------------------------CUGUACAGGCCACUGCCUUGu-- 39 0,-1 -------------------------------------------------------------CUGUACAGGCCACUGCCUUGuu- 2 0,-1 -------------------------------------------------------------CUGUACAGGCCACUGCCUUGC-- 306 0,0 -------------------------------------------------------------CUGUACAGGCCACUGCCUUGCa- 16 0,0 -------------------------------------------------------------CUGUACAGGCCACUGCCUUGCu- 468 0,0 -------------------------------------------------------------CUGUACAGGCCACUGCCUUGCCA 4 0,2 --------------------------------------------------------------UGUACAGGCCACUGCCUUGC-- 2 1,0 --------------------------------------------------------------UGUACAGGCCACUGCCUUGCu- 5 1,0 >hsa-let-7i MA:6-27;mi:62-83 Tumor cuggcUGAGGUAGUAGUUUGUGCUGUUggucggguugugacauugcccgcuguggagauaaCUGCGCAAGCUACUGCCUUGCUa ----CUGAGGUAGUAGUUUGUGCU------------------------------------------------------------ 2 -1,-3 ----CUGAGGUAGUAGUUUGUGCUG----------------------------------------------------------- 4 -1,-2 ----CUGAGGUAGUAGUUUGUGCUGU---------------------------------------------------------- 56 -1,-1 ----CUGAGGUAGUAGUUUGUGCUGUU--------------------------------------------------------- 423 -1,0 ----CUGAGGUAGUAGUUUGUGCUGUUa-------------------------------------------------------- 128 -1,0 ----CUGAGGUAGUAGUUUGUGCUGUUu-------------------------------------------------------- 50 -1,0 -----UGAGGUAGUAGUUUGUGC------------------------------------------------------------- 805 0,-4 -----UGAGGUAGUAGUUUGUGCa------------------------------------------------------------ 5 0,-4 -----UGAGGUAGUAGUUUGUGCaa----------------------------------------------------------- 2 0,-4 -----UGAGGUAGUAGUUUGUGCU------------------------------------------------------------ 2987 0,-3 -----UGAGGUAGUAGUUUGUGCUa----------------------------------------------------------- 138 0,-3 -----UGAGGUAGUAGUUUGUGCUaa---------------------------------------------------------- 47 0,-3 -----UGAGGUAGUAGUUUGUGCUau---------------------------------------------------------- 76 0,-3 -----UGAGGUAGUAGUUUGUGCUu----------------------------------------------------------- 118 0,-3 -----UGAGGUAGUAGUUUGUGCUuu---------------------------------------------------------- 217 0,-3 -----UGAGGUAGUAGUUUGUGCUG----------------------------------------------------------- 5431 0,-2 -----UGAGGUAGUAGUUUGUGCUGa---------------------------------------------------------- 831 0,-2 -----UGAGGUAGUAGUUUGUGCUGaa--------------------------------------------------------- 137 0,-2 -----UGAGGUAGUAGUUUGUGCUGau--------------------------------------------------------- 48 0,-2 -----UGAGGUAGUAGUUUGUGCUGc---------------------------------------------------------- 29 0,-2 -----UGAGGUAGUAGUUUGUGCUGg---------------------------------------------------------- 11 0,-2 -----UGAGGUAGUAGUUUGUGCUGU---------------------------------------------------------- 31407 0,-1 -----UGAGGUAGUAGUUUGUGCUGUa--------------------------------------------------------- 1756 0,-1 -----UGAGGUAGUAGUUUGUGCUGUaa-------------------------------------------------------- 2178 0,-1 -----UGAGGUAGUAGUUUGUGCUGUau-------------------------------------------------------- 453 0,-1 -----UGAGGUAGUAGUUUGUGCUGUc--------------------------------------------------------- 265 0,-1 -----UGAGGUAGUAGUUUGUGCUGUg--------------------------------------------------------- 44 0,-1 -----UGAGGUAGUAGUUUGUGCUGUU--------------------------------------------------------- 187848 0,0 -----UGAGGUAGUAGUUUGUGCUGUUa-------------------------------------------------------- 54527 0,0 -----UGAGGUAGUAGUUUGUGCUGUUaa------------------------------------------------------- 2061 0,0 -----UGAGGUAGUAGUUUGUGCUGUUau------------------------------------------------------- 2251 0,0 -----UGAGGUAGUAGUUUGUGCUGUUc-------------------------------------------------------- 383 0,0 -----UGAGGUAGUAGUUUGUGCUGUUu-------------------------------------------------------- 27329 0,0 -----UGAGGUAGUAGUUUGUGCUGUUuu------------------------------------------------------- 588 0,0 -----UGAGGUAGUAGUUUGUGCUGUUG-------------------------------------------------------- 2175 0,1 -----UGAGGUAGUAGUUUGUGCUGUUGa------------------------------------------------------- 156 0,1 -----UGAGGUAGUAGUUUGUGCUGUUGu------------------------------------------------------- 112 0,1 ------GAGGUAGUAGUUUGUGCU------------------------------------------------------------ 29 1,-3 ------GAGGUAGUAGUUUGUGCUG----------------------------------------------------------- 79 1,-2 ------GAGGUAGUAGUUUGUGCUGa---------------------------------------------------------- 14 1,-2 ------GAGGUAGUAGUUUGUGCUGU---------------------------------------------------------- 947 1,-1 ------GAGGUAGUAGUUUGUGCUGUa--------------------------------------------------------- 17 1,-1 ------GAGGUAGUAGUUUGUGCUGUaa-------------------------------------------------------- 31 1,-1 ------GAGGUAGUAGUUUGUGCUGUau-------------------------------------------------------- 5 1,-1 ------GAGGUAGUAGUUUGUGCUGUc--------------------------------------------------------- 2 1,-1 ------GAGGUAGUAGUUUGUGCUGUU--------------------------------------------------------- 5130 1,0 ------GAGGUAGUAGUUUGUGCUGUUa-------------------------------------------------------- 1551 1,0 ------GAGGUAGUAGUUUGUGCUGUUaa------------------------------------------------------- 28 1,0 ------GAGGUAGUAGUUUGUGCUGUUau------------------------------------------------------- 28 1,0 ------GAGGUAGUAGUUUGUGCUGUUc-------------------------------------------------------- 4 1,0 ------GAGGUAGUAGUUUGUGCUGUUu-------------------------------------------------------- 628 1,0 ------GAGGUAGUAGUUUGUGCUGUUuu------------------------------------------------------- 11 1,0 ------GAGGUAGUAGUUUGUGCUGUUG-------------------------------------------------------- 25 1,1 -------AGGUAGUAGUUUGUGCUGU---------------------------------------------------------- 10 2,-1 -------AGGUAGUAGUUUGUGCUGUU--------------------------------------------------------- 140 2,0 -------AGGUAGUAGUUUGUGCUGUUa-------------------------------------------------------- 17 2,0 -------AGGUAGUAGUUUGUGCUGUUu-------------------------------------------------------- 12 2,0 -------------------------------------------------------------CUGCGCAAGCUACUGCCU----- 4 0,-4 -------------------------------------------------------------CUGCGCAAGCUACUGCCUU---- 30 0,-3 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUa--- 6 0,-3 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUu--- 2 0,-3 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUG--- 568 0,-2 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGa-- 55 0,-2 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGau- 2 0,-2 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGu-- 19 0,-2 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGuu- 82 0,-2 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGC-- 1504 0,-1 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGCa- 111 0,-1 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGCc- 10 0,-1 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGCU- 3851 0,0 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGCUu 75 0,0 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGCUuu 56 0,0 -------------------------------------------------------------CUGCGCAAGCUACUGCCUUGCUA 2 0,1 --------------------------------------------------------------UGCGCAAGCUACUGCCUUG--- 12 1,-2 --------------------------------------------------------------UGCGCAAGCUACUGCCUUGC-- 24 1,-1 --------------------------------------------------------------UGCGCAAGCUACUGCCUUGCc- 4 1,-1 --------------------------------------------------------------UGCGCAAGCUACUGCCUUGCU- 103 1,0 >hsa-mir-1-1 3pM:46-67 Tumor ugggaaacauacuucuuuauaugcccauauggaccugcuaagcuaUGGAAUGUAAAGAAGUAUGUAUcuca ---------------------------------------------UGGAAUGUAAAGAAGUAUG------- 2 0,-3 ---------------------------------------------UGGAAUGUAAAGAAGUAUGU------ 91 0,-2 ---------------------------------------------UGGAAUGUAAAGAAGUAUGUA----- 34 0,-1 ---------------------------------------------UGGAAUGUAAAGAAGUAUGUAa---- 86 0,-1 ---------------------------------------------UGGAAUGUAAAGAAGUAUGUAc---- 3 0,-1 ---------------------------------------------UGGAAUGUAAAGAAGUAUGUAU---- 1341 0,0 ---------------------------------------------UGGAAUGUAAAGAAGUAUGUAUa--- 3 0,0 ----------------------------------------------GGAAUGUAAAGAAGUAUGU------ 2 1,-2 ----------------------------------------------GGAAUGUAAAGAAGUAUGUAU---- 8 1,0 >hsa-mir-1-2 3pM:53-74 Tumor accuacucagaguacauacuucuuuauguacccauaugaacauacaaugcuaUGGAAUGUAAAGAAGUAUGUAUuuuugguaggc ----------------------------------------------------UGGAAUGUAAAGAAGUAUG-------------- 2 0,-3 ----------------------------------------------------UGGAAUGUAAAGAAGUAUGU------------- 91 0,-2 ----------------------------------------------------UGGAAUGUAAAGAAGUAUGUA------------ 34 0,-1 ----------------------------------------------------UGGAAUGUAAAGAAGUAUGUAa----------- 86 0,-1 ----------------------------------------------------UGGAAUGUAAAGAAGUAUGUAc----------- 3 0,-1 ----------------------------------------------------UGGAAUGUAAAGAAGUAUGUAU----------- 1341 0,0 ----------------------------------------------------UGGAAUGUAAAGAAGUAUGUAUa---------- 3 0,0 ----------------------------------------------------UGGAAUGUAAAGAAGUAUGUAUU---------- 35 0,1 -----------------------------------------------------GGAAUGUAAAGAAGUAUGU------------- 2 1,-2 -----------------------------------------------------GGAAUGUAAAGAAGUAUGUAU----------- 8 1,0 -----------------------------------------------------GGAAUGUAAAGAAGUAUGUAUU---------- 2 1,1 >hsa-mir-100 MA:13-34;mi:48-69 Tumor ccuguugccacaAACCCGUAGAUCCGAACUUGUGguauuaguccgcaCAAGCUUGUAUCUAUAGGUAUGugucuguuagg ------------AACCCGUAGAUCCGAACU-------------------------------------------------- 96 0,-4 ------------AACCCGUAGAUCCGAACUU------------------------------------------------- 374 0,-3 ------------AACCCGUAGAUCCGAACUUau----------------------------------------------- 40 0,-3 ------------AACCCGUAGAUCCGAACUUuu----------------------------------------------- 36 0,-3 ------------AACCCGUAGAUCCGAACUUG------------------------------------------------ 1253 0,-2 ------------AACCCGUAGAUCCGAACUUGa----------------------------------------------- 54 0,-2 ------------AACCCGUAGAUCCGAACUUGaa---------------------------------------------- 2 0,-2 ------------AACCCGUAGAUCCGAACUUGc----------------------------------------------- 41 0,-2 ------------AACCCGUAGAUCCGAACUUGg----------------------------------------------- 36 0,-2 ------------AACCCGUAGAUCCGAACUUGU----------------------------------------------- 25612 0,-1 ------------AACCCGUAGAUCCGAACUUGUa---------------------------------------------- 133 0,-1 ------------AACCCGUAGAUCCGAACUUGUaa--------------------------------------------- 29 0,-1 ------------AACCCGUAGAUCCGAACUUGUau--------------------------------------------- 3 0,-1 ------------AACCCGUAGAUCCGAACUUGUc---------------------------------------------- 13 0,-1 ------------AACCCGUAGAUCCGAACUUGUu---------------------------------------------- 62 0,-1 ------------AACCCGUAGAUCCGAACUUGUuu--------------------------------------------- 2 0,-1 ------------AACCCGUAGAUCCGAACUUGUG---------------------------------------------- 24962 0,0 ------------AACCCGUAGAUCCGAACUUGUGa--------------------------------------------- 10723 0,0 ------------AACCCGUAGAUCCGAACUUGUGaa-------------------------------------------- 137 0,0 ------------AACCCGUAGAUCCGAACUUGUGau-------------------------------------------- 2 0,0 ------------AACCCGUAGAUCCGAACUUGUGc--------------------------------------------- 44 0,0 ------------AACCCGUAGAUCCGAACUUGUGu--------------------------------------------- 4032 0,0 ------------AACCCGUAGAUCCGAACUUGUGG--------------------------------------------- 107 0,1 ------------AACCCGUAGAUCCGAACUUGUGGU-------------------------------------------- 2 0,2 -------------ACCCGUAGAUCCGAACUU------------------------------------------------- 3 1,-3 -------------ACCCGUAGAUCCGAACUUG------------------------------------------------ 7 1,-2 -------------ACCCGUAGAUCCGAACUUGU----------------------------------------------- 810 1,-1 -------------ACCCGUAGAUCCGAACUUGUu---------------------------------------------- 2 1,-1 -------------ACCCGUAGAUCCGAACUUGUG---------------------------------------------- 792 1,0 -------------ACCCGUAGAUCCGAACUUGUGa--------------------------------------------- 320 1,0 -------------ACCCGUAGAUCCGAACUUGUGaa-------------------------------------------- 2 1,0 -------------ACCCGUAGAUCCGAACUUGUGu--------------------------------------------- 87 1,0 -----------------------------------------------CAAGCUUGUAUCUAUAGGUAU------------ 2 0,-1 -----------------------------------------------CAAGCUUGUAUCUAUAGGUAUG----------- 34 0,0 >hsa-mir-101-1 mi:11-32;MA:47-67 Tumor ugcccuggcuCAGUUAUCACAGUGCUGAUGCUgucuauucuaaaggUACAGUACUGUGAUAACUGAAggauggca ---------UCAGUUAUCACAGUGCUGA----------------------------------------------- 2 -1,-4 ---------UCAGUUAUCACAGUGCUGAaa--------------------------------------------- 2 -1,-4 ---------UCAGUUAUCACAGUGCUGAU---------------------------------------------- 20 -1,-3 ---------UCAGUUAUCACAGUGCUGAUa--------------------------------------------- 12 -1,-3 ---------UCAGUUAUCACAGUGCUGAUaa-------------------------------------------- 4 -1,-3 ---------UCAGUUAUCACAGUGCUGAUG--------------------------------------------- 285 -1,-2 ---------UCAGUUAUCACAGUGCUGAUGa-------------------------------------------- 42 -1,-2 ---------UCAGUUAUCACAGUGCUGAUGaa------------------------------------------- 4 -1,-2 ---------UCAGUUAUCACAGUGCUGAUGu-------------------------------------------- 5 -1,-2 ---------UCAGUUAUCACAGUGCUGAUGC-------------------------------------------- 505 -1,-1 ---------UCAGUUAUCACAGUGCUGAUGCa------------------------------------------- 2 -1,-1 ---------UCAGUUAUCACAGUGCUGAUGCU------------------------------------------- 178 -1,0 ----------CAGUUAUCACAGUGCUGAU---------------------------------------------- 3 0,-3 ----------CAGUUAUCACAGUGCUGAUa--------------------------------------------- 2 0,-3 ----------CAGUUAUCACAGUGCUGAUG--------------------------------------------- 98 0,-2 ----------CAGUUAUCACAGUGCUGAUGu-------------------------------------------- 14 0,-2 ----------CAGUUAUCACAGUGCUGAUGC-------------------------------------------- 113 0,-1 ----------CAGUUAUCACAGUGCUGAUGCa------------------------------------------- 2 0,-1 ----------CAGUUAUCACAGUGCUGAUGCU------------------------------------------- 109 0,0 -----------AGUUAUCACAGUGCUGAUGC-------------------------------------------- 4 1,-1 -----------AGUUAUCACAGUGCUGAUGCU------------------------------------------- 2 1,0 --------------------------------------------GGUACAGUACUGUGAUAACUGA--------- 4 -2,-1 --------------------------------------------GGUACAGUACUGUGAUAACUGAA-------- 4 -2,0 ---------------------------------------------GUACAGUACUGUGAUAAC------------ 251 -1,-4 ---------------------------------------------GUACAGUACUGUGAUAACa----------- 34 -1,-4 ---------------------------------------------GUACAGUACUGUGAUAACU----------- 3437 -1,-3 ---------------------------------------------GUACAGUACUGUGAUAACUa---------- 45 -1,-3 ---------------------------------------------GUACAGUACUGUGAUAACUaa--------- 162 -1,-3 ---------------------------------------------GUACAGUACUGUGAUAACUu---------- 19 -1,-3 ---------------------------------------------GUACAGUACUGUGAUAACUuu--------- 2 -1,-3 ---------------------------------------------GUACAGUACUGUGAUAACUG---------- 4602 -1,-2 ---------------------------------------------GUACAGUACUGUGAUAACUGc--------- 150 -1,-2 ---------------------------------------------GUACAGUACUGUGAUAACUGg--------- 52 -1,-2 ---------------------------------------------GUACAGUACUGUGAUAACUGu--------- 1068 -1,-2 ---------------------------------------------GUACAGUACUGUGAUAACUGuu-------- 14 -1,-2 ---------------------------------------------GUACAGUACUGUGAUAACUGA--------- 74055 -1,-1 ---------------------------------------------GUACAGUACUGUGAUAACUGAc-------- 913 -1,-1 ---------------------------------------------GUACAGUACUGUGAUAACUGAg-------- 154 -1,-1 ---------------------------------------------GUACAGUACUGUGAUAACUGAu-------- 1945 -1,-1 ---------------------------------------------GUACAGUACUGUGAUAACUGAuu------- 52 -1,-1 ---------------------------------------------GUACAGUACUGUGAUAACUGAA-------- 38902 -1,0 ---------------------------------------------GUACAGUACUGUGAUAACUGAAa------- 8914 -1,0 ---------------------------------------------GUACAGUACUGUGAUAACUGAAaa------ 162 -1,0 ---------------------------------------------GUACAGUACUGUGAUAACUGAAau------ 16 -1,0 ---------------------------------------------GUACAGUACUGUGAUAACUGAAc------- 38 -1,0 ---------------------------------------------GUACAGUACUGUGAUAACUGAAu------- 2220 -1,0 ---------------------------------------------GUACAGUACUGUGAUAACUGAAuu------ 12 -1,0 ---------------------------------------------GUACAGUACUGUGAUAACUGAAG------- 653 -1,1 ---------------------------------------------GUACAGUACUGUGAUAACUGAAGu------ 4 -1,1 ----------------------------------------------UACAGUACUGUGAUAACU----------- 889 0,-3 ----------------------------------------------UACAGUACUGUGAUAACUa---------- 12 0,-3 ----------------------------------------------UACAGUACUGUGAUAACUaa--------- 44 0,-3 ----------------------------------------------UACAGUACUGUGAUAACUG---------- 2371 0,-2 ----------------------------------------------UACAGUACUGUGAUAACUGc--------- 53 0,-2 ----------------------------------------------UACAGUACUGUGAUAACUGg--------- 20 0,-2 ----------------------------------------------UACAGUACUGUGAUAACUGu--------- 422 0,-2 ----------------------------------------------UACAGUACUGUGAUAACUGuu-------- 5 0,-2 ----------------------------------------------UACAGUACUGUGAUAACUGA--------- 29183 0,-1 ----------------------------------------------UACAGUACUGUGAUAACUGAc-------- 687 0,-1 ----------------------------------------------UACAGUACUGUGAUAACUGAg-------- 51 0,-1 ----------------------------------------------UACAGUACUGUGAUAACUGAu-------- 897 0,-1 ----------------------------------------------UACAGUACUGUGAUAACUGAuu------- 1258 0,-1 ----------------------------------------------UACAGUACUGUGAUAACUGAA-------- 28339 0,0 ----------------------------------------------UACAGUACUGUGAUAACUGAAa------- 14920 0,0 ----------------------------------------------UACAGUACUGUGAUAACUGAAaa------ 680 0,0 ----------------------------------------------UACAGUACUGUGAUAACUGAAau------ 73 0,0 ----------------------------------------------UACAGUACUGUGAUAACUGAAc------- 433 0,0 ----------------------------------------------UACAGUACUGUGAUAACUGAAu------- 25618 0,0 ----------------------------------------------UACAGUACUGUGAUAACUGAAuu------ 364 0,0 ----------------------------------------------UACAGUACUGUGAUAACUGAAG------- 67637 0,1 ----------------------------------------------UACAGUACUGUGAUAACUGAAGc------ 10 0,1 ----------------------------------------------UACAGUACUGUGAUAACUGAAGu------ 3758 0,1 ----------------------------------------------UACAGUACUGUGAUAACUGAAGuu----- 30 0,1 ----------------------------------------------UACAGUACUGUGAUAACUGAAGG------ 6 0,2 ----------------------------------------------UACAGUACUGUGAUAACUGAAGGA----- 2 0,3 -----------------------------------------------ACAGUACUGUGAUAACUG---------- 56 1,-2 -----------------------------------------------ACAGUACUGUGAUAACUGu--------- 4 1,-2 -----------------------------------------------ACAGUACUGUGAUAACUGA--------- 1228 1,-1 -----------------------------------------------ACAGUACUGUGAUAACUGAc-------- 8 1,-1 -----------------------------------------------ACAGUACUGUGAUAACUGAu-------- 22 1,-1 -----------------------------------------------ACAGUACUGUGAUAACUGAuu------- 39 1,-1 -----------------------------------------------ACAGUACUGUGAUAACUGAA-------- 1359 1,0 -----------------------------------------------ACAGUACUGUGAUAACUGAAa------- 723 1,0 -----------------------------------------------ACAGUACUGUGAUAACUGAAaa------ 23 1,0 -----------------------------------------------ACAGUACUGUGAUAACUGAAau------ 2 1,0 -----------------------------------------------ACAGUACUGUGAUAACUGAAc------- 17 1,0 -----------------------------------------------ACAGUACUGUGAUAACUGAAu------- 1264 1,0 -----------------------------------------------ACAGUACUGUGAUAACUGAAuu------ 21 1,0 -----------------------------------------------ACAGUACUGUGAUAACUGAAG------- 3291 1,1 -----------------------------------------------ACAGUACUGUGAUAACUGAAGu------ 197 1,1 ------------------------------------------------CAGUACUGUGAUAACUGA--------- 50 2,-1 ------------------------------------------------CAGUACUGUGAUAACUGAA-------- 66 2,0 ------------------------------------------------CAGUACUGUGAUAACUGAAa------- 34 2,0 ------------------------------------------------CAGUACUGUGAUAACUGAAaa------ 2 2,0 ------------------------------------------------CAGUACUGUGAUAACUGAAu------- 63 2,0 ------------------------------------------------CAGUACUGUGAUAACUGAAuu------ 22 2,0 ------------------------------------------------CAGUACUGUGAUAACUGAAG------- 174 2,1 ------------------------------------------------CAGUACUGUGAUAACUGAAGu------ 41 2,1 ------------------------------------------------CAGUACUGUGAUAACUGAAGuu----- 10 2,1 >hsa-mir-101-2 3pM:49-69 Tumor acuguccuuuuucgguuaucaugguaccgaugcuguauaucugaaaggUACAGUACUGUGAUAACUGAAgaaugguggu -----------UCGGUUAUCAUGGUACCGAUGCU--------------------------------------------- 3 ------------CGGUUAUCAUGGUACCGAUGCU--------------------------------------------- 4 ----------------------------------------------GGUACAGUACUGUGAUAACUGA----------- 4 -2,-1 ----------------------------------------------GGUACAGUACUGUGAUAACUGAA---------- 4 -2,0 -----------------------------------------------GUACAGUACUGUGAUAAC-------------- 251 -1,-4 -----------------------------------------------GUACAGUACUGUGAUAACa------------- 34 -1,-4 -----------------------------------------------GUACAGUACUGUGAUAACU------------- 3437 -1,-3 -----------------------------------------------GUACAGUACUGUGAUAACUa------------ 45 -1,-3 -----------------------------------------------GUACAGUACUGUGAUAACUaa----------- 162 -1,-3 -----------------------------------------------GUACAGUACUGUGAUAACUu------------ 19 -1,-3 -----------------------------------------------GUACAGUACUGUGAUAACUuu----------- 2 -1,-3 -----------------------------------------------GUACAGUACUGUGAUAACUG------------ 4602 -1,-2 -----------------------------------------------GUACAGUACUGUGAUAACUGc----------- 150 -1,-2 -----------------------------------------------GUACAGUACUGUGAUAACUGg----------- 52 -1,-2 -----------------------------------------------GUACAGUACUGUGAUAACUGu----------- 1068 -1,-2 -----------------------------------------------GUACAGUACUGUGAUAACUGuu---------- 14 -1,-2 -----------------------------------------------GUACAGUACUGUGAUAACUGA----------- 74055 -1,-1 -----------------------------------------------GUACAGUACUGUGAUAACUGAc---------- 913 -1,-1 -----------------------------------------------GUACAGUACUGUGAUAACUGAg---------- 154 -1,-1 -----------------------------------------------GUACAGUACUGUGAUAACUGAu---------- 1945 -1,-1 -----------------------------------------------GUACAGUACUGUGAUAACUGAuu--------- 52 -1,-1 -----------------------------------------------GUACAGUACUGUGAUAACUGAA---------- 38902 -1,0 -----------------------------------------------GUACAGUACUGUGAUAACUGAAa--------- 8914 -1,0 -----------------------------------------------GUACAGUACUGUGAUAACUGAAaa-------- 162 -1,0 -----------------------------------------------GUACAGUACUGUGAUAACUGAAau-------- 16 -1,0 -----------------------------------------------GUACAGUACUGUGAUAACUGAAc--------- 38 -1,0 -----------------------------------------------GUACAGUACUGUGAUAACUGAAu--------- 2220 -1,0 -----------------------------------------------GUACAGUACUGUGAUAACUGAAuu-------- 12 -1,0 -----------------------------------------------GUACAGUACUGUGAUAACUGAAG--------- 653 -1,1 -----------------------------------------------GUACAGUACUGUGAUAACUGAAGu-------- 4 -1,1 -----------------------------------------------GUACAGUACUGUGAUAACUGAAGA-------- 2 -1,2 ------------------------------------------------UACAGUACUGUGAUAACU------------- 889 0,-3 ------------------------------------------------UACAGUACUGUGAUAACUa------------ 12 0,-3 ------------------------------------------------UACAGUACUGUGAUAACUaa----------- 44 0,-3 ------------------------------------------------UACAGUACUGUGAUAACUG------------ 2371 0,-2 ------------------------------------------------UACAGUACUGUGAUAACUGc----------- 53 0,-2 ------------------------------------------------UACAGUACUGUGAUAACUGg----------- 20 0,-2 ------------------------------------------------UACAGUACUGUGAUAACUGu----------- 422 0,-2 ------------------------------------------------UACAGUACUGUGAUAACUGuu---------- 5 0,-2 ------------------------------------------------UACAGUACUGUGAUAACUGA----------- 29183 0,-1 ------------------------------------------------UACAGUACUGUGAUAACUGAc---------- 687 0,-1 ------------------------------------------------UACAGUACUGUGAUAACUGAg---------- 51 0,-1 ------------------------------------------------UACAGUACUGUGAUAACUGAu---------- 897 0,-1 ------------------------------------------------UACAGUACUGUGAUAACUGAuu--------- 1258 0,-1 ------------------------------------------------UACAGUACUGUGAUAACUGAA---------- 28339 0,0 ------------------------------------------------UACAGUACUGUGAUAACUGAAa--------- 14920 0,0 ------------------------------------------------UACAGUACUGUGAUAACUGAAaa-------- 680 0,0 ------------------------------------------------UACAGUACUGUGAUAACUGAAau-------- 73 0,0 ------------------------------------------------UACAGUACUGUGAUAACUGAAc--------- 433 0,0 ------------------------------------------------UACAGUACUGUGAUAACUGAAu--------- 25618 0,0 ------------------------------------------------UACAGUACUGUGAUAACUGAAuu-------- 364 0,0 ------------------------------------------------UACAGUACUGUGAUAACUGAAG--------- 67637 0,1 ------------------------------------------------UACAGUACUGUGAUAACUGAAGc-------- 10 0,1 ------------------------------------------------UACAGUACUGUGAUAACUGAAGu-------- 3758 0,1 ------------------------------------------------UACAGUACUGUGAUAACUGAAGuu------- 30 0,1 ------------------------------------------------UACAGUACUGUGAUAACUGAAGA-------- 2982 0,2 ------------------------------------------------UACAGUACUGUGAUAACUGAAGAu------- 8 0,2 ------------------------------------------------UACAGUACUGUGAUAACUGAAGAA------- 208 0,3 ------------------------------------------------UACAGUACUGUGAUAACUGAAGAAa------ 9 0,3 ------------------------------------------------UACAGUACUGUGAUAACUGAAGAAg------ 2 0,3 -------------------------------------------------ACAGUACUGUGAUAACUG------------ 56 1,-2 -------------------------------------------------ACAGUACUGUGAUAACUGu----------- 4 1,-2 -------------------------------------------------ACAGUACUGUGAUAACUGA----------- 1228 1,-1 -------------------------------------------------ACAGUACUGUGAUAACUGAc---------- 8 1,-1 -------------------------------------------------ACAGUACUGUGAUAACUGAu---------- 22 1,-1 -------------------------------------------------ACAGUACUGUGAUAACUGAuu--------- 39 1,-1 -------------------------------------------------ACAGUACUGUGAUAACUGAA---------- 1359 1,0 -------------------------------------------------ACAGUACUGUGAUAACUGAAa--------- 723 1,0 -------------------------------------------------ACAGUACUGUGAUAACUGAAaa-------- 23 1,0 -------------------------------------------------ACAGUACUGUGAUAACUGAAau-------- 2 1,0 -------------------------------------------------ACAGUACUGUGAUAACUGAAc--------- 17 1,0 -------------------------------------------------ACAGUACUGUGAUAACUGAAu--------- 1264 1,0 -------------------------------------------------ACAGUACUGUGAUAACUGAAuu-------- 21 1,0 -------------------------------------------------ACAGUACUGUGAUAACUGAAG--------- 3291 1,1 -------------------------------------------------ACAGUACUGUGAUAACUGAAGu-------- 197 1,1 -------------------------------------------------ACAGUACUGUGAUAACUGAAGA-------- 148 1,2 -------------------------------------------------ACAGUACUGUGAUAACUGAAGAA------- 2 1,3 --------------------------------------------------CAGUACUGUGAUAACUGA----------- 50 2,-1 --------------------------------------------------CAGUACUGUGAUAACUGAA---------- 66 2,0 --------------------------------------------------CAGUACUGUGAUAACUGAAa--------- 34 2,0 --------------------------------------------------CAGUACUGUGAUAACUGAAaa-------- 2 2,0 --------------------------------------------------CAGUACUGUGAUAACUGAAu--------- 63 2,0 --------------------------------------------------CAGUACUGUGAUAACUGAAuu-------- 22 2,0 --------------------------------------------------CAGUACUGUGAUAACUGAAG--------- 174 2,1 --------------------------------------------------CAGUACUGUGAUAACUGAAGu-------- 41 2,1 --------------------------------------------------CAGUACUGUGAUAACUGAAGuu------- 10 2,1 --------------------------------------------------CAGUACUGUGAUAACUGAAGA-------- 23 2,2 --------------------------------------------------CAGUACUGUGAUAACUGAAGAAa------ 4 2,3 >hsa-mir-103a-1 3pM:48-70 Tumor uacugcccucggcuucuuuacagugcugccuuguugcauauggaucaAGCAGCAUUGUACAGGGCUAUGAaggcauug -----------GCUUCUUUACAGUGCUGCCUUGU-------------------------------------------- 2 ----------------UUUACAGUGCUGCCUUGU-------------------------------------------- 2 ---------------------------------------------CAAGCAGCAUUGUACAGGGCUAUGA-------- 2 -2,0 ----------------------------------------------AAGCAGCAUUGUACAGGGCUAU---------- 5 -1,-2 ----------------------------------------------AAGCAGCAUUGUACAGGGCUAUGu-------- 2 -1,-1 ----------------------------------------------AAGCAGCAUUGUACAGGGCUAUGA-------- 9 -1,0 -----------------------------------------------AGCAGCAUUGUACAGGGC------------- 1068 0,-5 -----------------------------------------------AGCAGCAUUGUACAGGGCa------------ 4 0,-5 -----------------------------------------------AGCAGCAUUGUACAGGGCaa----------- 18 0,-5 -----------------------------------------------AGCAGCAUUGUACAGGGCc------------ 2 0,-5 -----------------------------------------------AGCAGCAUUGUACAGGGCU------------ 6141 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUc----------- 2 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUg----------- 7 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUu----------- 939 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUuu---------- 554 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUA----------- 5946 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAa---------- 1967 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAaa--------- 952 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAau--------- 350 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAc---------- 78 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAg---------- 110 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAU---------- 61415 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUa--------- 4219 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUaa-------- 4922 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUau-------- 1467 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUu--------- 7060 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUuu-------- 1279 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUG--------- 55592 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGc-------- 1518 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGg-------- 596 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGu-------- 46223 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGuu------- 2805 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGA-------- 351936 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAc------- 206 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAg------- 791 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAu------- 18512 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAuu------ 645 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAA------- 19744 0,1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAAc------ 8 0,1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAAu------ 1232 0,1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAAG------ 30 0,2 ------------------------------------------------GCAGCAUUGUACAGGGCU------------ 94 1,-4 ------------------------------------------------GCAGCAUUGUACAGGGCUc----------- 2 1,-4 ------------------------------------------------GCAGCAUUGUACAGGGCUu----------- 5 1,-4 ------------------------------------------------GCAGCAUUGUACAGGGCUuu---------- 6 1,-4 ------------------------------------------------GCAGCAUUGUACAGGGCUA----------- 56 1,-3 ------------------------------------------------GCAGCAUUGUACAGGGCUAa---------- 10 1,-3 ------------------------------------------------GCAGCAUUGUACAGGGCUAau--------- 2 1,-3 ------------------------------------------------GCAGCAUUGUACAGGGCUAc---------- 2 1,-3 ------------------------------------------------GCAGCAUUGUACAGGGCUAU---------- 1010 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUa--------- 41 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUaa-------- 56 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUau-------- 2 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUu--------- 84 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUuu-------- 6 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUG--------- 911 1,-1 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGc-------- 25 1,-1 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGg-------- 2 1,-1 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGu-------- 719 1,-1 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGuu------- 24 1,-1 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGA-------- 6290 1,0 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGAg------- 5 1,0 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGAu------- 308 1,0 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGAuu------ 2 1,0 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGAA------- 309 1,1 -------------------------------------------------CAGCAUUGUACAGGGCUA----------- 6 2,-3 -------------------------------------------------CAGCAUUGUACAGGGCUAU---------- 58 2,-2 -------------------------------------------------CAGCAUUGUACAGGGCUAUa--------- 2 2,-2 -------------------------------------------------CAGCAUUGUACAGGGCUAUaa-------- 2 2,-2 -------------------------------------------------CAGCAUUGUACAGGGCUAUu--------- 2 2,-2 -------------------------------------------------CAGCAUUGUACAGGGCUAUG--------- 162 2,-1 -------------------------------------------------CAGCAUUGUACAGGGCUAUGc-------- 5 2,-1 -------------------------------------------------CAGCAUUGUACAGGGCUAUGu-------- 94 2,-1 -------------------------------------------------CAGCAUUGUACAGGGCUAUGA-------- 2707 2,0 -------------------------------------------------CAGCAUUGUACAGGGCUAUGAu------- 109 2,0 -------------------------------------------------CAGCAUUGUACAGGGCUAUGAA------- 220 2,1 -------------------------------------------------CAGCAUUGUACAGGGCUAUGAAu------ 5 2,1 >hsa-mir-103a-2 mi:11-33;MA:48-70 Tumor uugugcuuucAGCUUCUUUACAGUGCUGCCUUGuagcauucaggucaAGCAGCAUUGUACAGGGCUAUGAaagaacca ----------AGCUUCUUUACAGUGCUGCC------------------------------------------------ 4 0,-3 ----------AGCUUCUUUACAGUGCUGCCa----------------------------------------------- 2 0,-3 ----------AGCUUCUUUACAGUGCUGCCU----------------------------------------------- 13 0,-2 ----------AGCUUCUUUACAGUGCUGCCUU---------------------------------------------- 11 0,-1 ----------AGCUUCUUUACAGUGCUGCCUUa--------------------------------------------- 3 0,-1 ----------AGCUUCUUUACAGUGCUGCCUUu--------------------------------------------- 13 0,-1 ----------AGCUUCUUUACAGUGCUGCCUUuu-------------------------------------------- 4 0,-1 ----------AGCUUCUUUACAGUGCUGCCUUG--------------------------------------------- 277 0,0 ----------AGCUUCUUUACAGUGCUGCCUUGa-------------------------------------------- 160 0,0 ----------AGCUUCUUUACAGUGCUGCCUUGau------------------------------------------- 4 0,0 ----------AGCUUCUUUACAGUGCUGCCUUGU-------------------------------------------- 275 0,1 ----------AGCUUCUUUACAGUGCUGCCUUGUA------------------------------------------- 2 0,2 -----------GCUUCUUUACAGUGCUGCCUUGU-------------------------------------------- 2 1,1 ---------------------------------------------CAAGCAGCAUUGUACAGGGCUAUGA-------- 2 -2,0 ----------------------------------------------AAGCAGCAUUGUACAGGGCUAU---------- 5 -1,-2 ----------------------------------------------AAGCAGCAUUGUACAGGGCUAUGu-------- 2 -1,-1 ----------------------------------------------AAGCAGCAUUGUACAGGGCUAUGA-------- 9 -1,0 -----------------------------------------------AGCAGCAUUGUACAGGGC------------- 1068 0,-5 -----------------------------------------------AGCAGCAUUGUACAGGGCa------------ 4 0,-5 -----------------------------------------------AGCAGCAUUGUACAGGGCaa----------- 18 0,-5 -----------------------------------------------AGCAGCAUUGUACAGGGCc------------ 2 0,-5 -----------------------------------------------AGCAGCAUUGUACAGGGCU------------ 6141 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUc----------- 2 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUg----------- 7 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUu----------- 939 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUuu---------- 554 0,-4 -----------------------------------------------AGCAGCAUUGUACAGGGCUA----------- 5946 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAa---------- 1967 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAaa--------- 952 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAau--------- 350 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAc---------- 78 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAg---------- 110 0,-3 -----------------------------------------------AGCAGCAUUGUACAGGGCUAU---------- 61415 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUa--------- 4219 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUaa-------- 4922 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUau-------- 1467 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUu--------- 7060 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUuu-------- 1279 0,-2 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUG--------- 55592 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGc-------- 1518 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGg-------- 596 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGu-------- 46223 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGuu------- 2805 0,-1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGA-------- 351936 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAc------- 206 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAg------- 791 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAu------- 18512 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAuu------ 645 0,0 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAA------- 19744 0,1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAAc------ 8 0,1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAAu------ 1232 0,1 -----------------------------------------------AGCAGCAUUGUACAGGGCUAUGAAA------ 1551 0,2 ------------------------------------------------GCAGCAUUGUACAGGGCU------------ 94 1,-4 ------------------------------------------------GCAGCAUUGUACAGGGCUc----------- 2 1,-4 ------------------------------------------------GCAGCAUUGUACAGGGCUu----------- 5 1,-4 ------------------------------------------------GCAGCAUUGUACAGGGCUuu---------- 6 1,-4 ------------------------------------------------GCAGCAUUGUACAGGGCUA----------- 56 1,-3 ------------------------------------------------GCAGCAUUGUACAGGGCUAa---------- 10 1,-3 ------------------------------------------------GCAGCAUUGUACAGGGCUAau--------- 2 1,-3 ------------------------------------------------GCAGCAUUGUACAGGGCUAc---------- 2 1,-3 ------------------------------------------------GCAGCAUUGUACAGGGCUAU---------- 1010 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUa--------- 41 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUaa-------- 56 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUau-------- 2 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUu--------- 84 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUuu-------- 6 1,-2 ------------------------------------------------GCAGCAUUGUACAGGGCUAUG--------- 911 1,-1 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGc-------- 25 1,-1 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGg-------- 2 1,-1 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGu-------- 719 1,-1 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGuu------- 24 1,-1 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGA-------- 6290 1,0 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGAg------- 5 1,0 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGAu------- 308 1,0 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGAuu------ 2 1,0 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGAA------- 309 1,1 ------------------------------------------------GCAGCAUUGUACAGGGCUAUGAAA------ 8 1,2 -------------------------------------------------CAGCAUUGUACAGGGCUA----------- 6 2,-3 -------------------------------------------------CAGCAUUGUACAGGGCUAU---------- 58 2,-2 -------------------------------------------------CAGCAUUGUACAGGGCUAUa--------- 2 2,-2 -------------------------------------------------CAGCAUUGUACAGGGCUAUaa-------- 2 2,-2 -------------------------------------------------CAGCAUUGUACAGGGCUAUu--------- 2 2,-2 -------------------------------------------------CAGCAUUGUACAGGGCUAUG--------- 162 2,-1 -------------------------------------------------CAGCAUUGUACAGGGCUAUGc-------- 5 2,-1 -------------------------------------------------CAGCAUUGUACAGGGCUAUGu-------- 94 2,-1 -------------------------------------------------CAGCAUUGUACAGGGCUAUGA-------- 2707 2,0 -------------------------------------------------CAGCAUUGUACAGGGCUAUGAu------- 109 2,0 -------------------------------------------------CAGCAUUGUACAGGGCUAUGAA------- 220 2,1 -------------------------------------------------CAGCAUUGUACAGGGCUAUGAAu------ 5 2,1 -------------------------------------------------CAGCAUUGUACAGGGCUAUGAAA------ 31 2,2 >hsa-mir-105-1 MA:13-35;mi:51-72 Tumor ugugcaucguggUCAAAUGCUCAGACUCCUGUGGUggcugcucaugcaccACGGAUGUUUGAGCAUGUGCUAcggugucua ------------UCAAAUGCUCAGACUCCUGUGa----------------------------------------------- 2 0,-2 ------------UCAAAUGCUCAGACUCCUGUGG----------------------------------------------- 16 0,-1 ------------UCAAAUGCUCAGACUCCUGUGGa---------------------------------------------- 2 0,-1 ------------UCAAAUGCUCAGACUCCUGUGGU---------------------------------------------- 45 0,0 ------------UCAAAUGCUCAGACUCCUGUGGUa--------------------------------------------- 2 0,0 ------------UCAAAUGCUCAGACUCCUGUGGUu--------------------------------------------- 2 0,0 ------------UCAAAUGCUCAGACUCCUGUGGUuu-------------------------------------------- 2 0,0 ------------UCAAAUGCUCAGACUCCUGUGGUG--------------------------------------------- 2 0,1 ------------UCAAAUGCUCAGACUCCUGUGGUGu-------------------------------------------- 5 0,1 --------------AAAUGCUCAGACUCCUGUGa----------------------------------------------- 2 2,-2 --------------AAAUGCUCAGACUCCUGUGGU---------------------------------------------- 22 2,0 --------------AAAUGCUCAGACUCCUGUGGUau-------------------------------------------- 2 2,0 --------------AAAUGCUCAGACUCCUGUGGUG--------------------------------------------- 56 2,1 --------------AAAUGCUCAGACUCCUGUGGUGa-------------------------------------------- 15 2,1 --------------AAAUGCUCAGACUCCUGUGGUGu-------------------------------------------- 46 2,1 --------------AAAUGCUCAGACUCCUGUGGUGuu------------------------------------------- 2 2,1 ------------------------------------------------CCACGGAUGUUUGAGCAUGUG------------ 3 -2,-3 ------------------------------------------------CCACGGAUGUUUGAGCAUGUGu----------- 4 -2,-3 ------------------------------------------------CCACGGAUGUUUGAGCAUGUGCU---------- 2 -2,-1 >hsa-mir-105-2 MA:13-35;mi:51-72 Tumor ugugcaucguggUCAAAUGCUCAGACUCCUGUGGUggcugcuuaugcaccACGGAUGUUUGAGCAUGUGCUAuggugucua ------------UCAAAUGCUCAGACUCCUGUGa----------------------------------------------- 2 0,-2 ------------UCAAAUGCUCAGACUCCUGUGG----------------------------------------------- 16 0,-1 ------------UCAAAUGCUCAGACUCCUGUGGa---------------------------------------------- 2 0,-1 ------------UCAAAUGCUCAGACUCCUGUGGU---------------------------------------------- 45 0,0 ------------UCAAAUGCUCAGACUCCUGUGGUa--------------------------------------------- 2 0,0 ------------UCAAAUGCUCAGACUCCUGUGGUu--------------------------------------------- 2 0,0 ------------UCAAAUGCUCAGACUCCUGUGGUuu-------------------------------------------- 2 0,0 ------------UCAAAUGCUCAGACUCCUGUGGUG--------------------------------------------- 2 0,1 ------------UCAAAUGCUCAGACUCCUGUGGUGu-------------------------------------------- 5 0,1 --------------AAAUGCUCAGACUCCUGUGa----------------------------------------------- 2 2,-2 --------------AAAUGCUCAGACUCCUGUGGU---------------------------------------------- 22 2,0 --------------AAAUGCUCAGACUCCUGUGGUau-------------------------------------------- 2 2,0 --------------AAAUGCUCAGACUCCUGUGGUG--------------------------------------------- 56 2,1 --------------AAAUGCUCAGACUCCUGUGGUGa-------------------------------------------- 15 2,1 --------------AAAUGCUCAGACUCCUGUGGUGu-------------------------------------------- 46 2,1 --------------AAAUGCUCAGACUCCUGUGGUGuu------------------------------------------- 2 2,1 ------------------------------------------------CCACGGAUGUUUGAGCAUGUG------------ 3 -2,-3 ------------------------------------------------CCACGGAUGUUUGAGCAUGUGu----------- 4 -2,-3 ------------------------------------------------CCACGGAUGUUUGAGCAUGUGCU---------- 2 -2,-1 >hsa-mir-106a MA:13-35;mi:50-71 Tumor ccuuggccauguAAAAGUGCUUACAGUGCAGGUAGcuuuuugagaucuaCUGCAAUGUAAGCACUUCUUACauuaccaugg -----------UAAAAGUGCUUACAGUGCAGGa------------------------------------------------ 2 -1,-3 ------------AAAAGUGCUUACAGUGCA--------------------------------------------------- 4 0,-5 ------------AAAAGUGCUUACAGUGCAG-------------------------------------------------- 19 0,-4 ------------AAAAGUGCUUACAGUGCAGa------------------------------------------------- 2 0,-4 ------------AAAAGUGCUUACAGUGCAGG------------------------------------------------- 48 0,-3 ------------AAAAGUGCUUACAGUGCAGGa------------------------------------------------ 12 0,-3 ------------AAAAGUGCUUACAGUGCAGGU------------------------------------------------ 306 0,-2 ------------AAAAGUGCUUACAGUGCAGGUu----------------------------------------------- 14 0,-2 ------------AAAAGUGCUUACAGUGCAGGUuu---------------------------------------------- 5 0,-2 ------------AAAAGUGCUUACAGUGCAGGUA----------------------------------------------- 428 0,-1 ------------AAAAGUGCUUACAGUGCAGGUAa---------------------------------------------- 88 0,-1 ------------AAAAGUGCUUACAGUGCAGGUAau--------------------------------------------- 2 0,-1 ------------AAAAGUGCUUACAGUGCAGGUAu---------------------------------------------- 206 0,-1 ------------AAAAGUGCUUACAGUGCAGGUAuu--------------------------------------------- 11 0,-1 ------------AAAAGUGCUUACAGUGCAGGUAG---------------------------------------------- 1916 0,0 ------------AAAAGUGCUUACAGUGCAGGUAGa--------------------------------------------- 135 0,0 ------------AAAAGUGCUUACAGUGCAGGUAGu--------------------------------------------- 199 0,0 ------------AAAAGUGCUUACAGUGCAGGUAGuu-------------------------------------------- 2 0,0 -------------AAAGUGCUUACAGUGCAG-------------------------------------------------- 46 1,-4 -------------AAAGUGCUUACAGUGCAGa------------------------------------------------- 3 1,-4 -------------AAAGUGCUUACAGUGCAGaa------------------------------------------------ 4 1,-4 -------------AAAGUGCUUACAGUGCAGG------------------------------------------------- 74 1,-3 -------------AAAGUGCUUACAGUGCAGGa------------------------------------------------ 16 1,-3 -------------AAAGUGCUUACAGUGCAGGaa----------------------------------------------- 18 1,-3 -------------AAAGUGCUUACAGUGCAGGau----------------------------------------------- 5 1,-3 -------------AAAGUGCUUACAGUGCAGGg------------------------------------------------ 3 1,-3 -------------AAAGUGCUUACAGUGCAGGU------------------------------------------------ 401 1,-2 -------------AAAGUGCUUACAGUGCAGGUu----------------------------------------------- 12 1,-2 -------------AAAGUGCUUACAGUGCAGGUuu---------------------------------------------- 3 1,-2 -------------AAAGUGCUUACAGUGCAGGUA----------------------------------------------- 570 1,-1 -------------AAAGUGCUUACAGUGCAGGUAa---------------------------------------------- 276 1,-1 -------------AAAGUGCUUACAGUGCAGGUAaa--------------------------------------------- 4 1,-1 -------------AAAGUGCUUACAGUGCAGGUAc---------------------------------------------- 2 1,-1 -------------AAAGUGCUUACAGUGCAGGUAu---------------------------------------------- 252 1,-1 -------------AAAGUGCUUACAGUGCAGGUAuu--------------------------------------------- 2 1,-1 -------------AAAGUGCUUACAGUGCAGGUAG---------------------------------------------- 2482 1,0 -------------AAAGUGCUUACAGUGCAGGUAGa--------------------------------------------- 227 1,0 -------------AAAGUGCUUACAGUGCAGGUAGaa-------------------------------------------- 2 1,0 -------------AAAGUGCUUACAGUGCAGGUAGC--------------------------------------------- 66 1,1 -------------AAAGUGCUUACAGUGCAGGUAGCU-------------------------------------------- 2 1,2 --------------AAGUGCUUACAGUGCAGGUAu---------------------------------------------- 2 2,-1 --------------AAGUGCUUACAGUGCAGGUAG---------------------------------------------- 33 2,0 --------------AAGUGCUUACAGUGCAGGUAGa--------------------------------------------- 2 2,0 -----------------------------------------------UACUGCAAUGUAAGCACUUC-------------- 4 -2,-4 -----------------------------------------------UACUGCAAUGUAAGCACUUCU------------- 19 -2,-3 -----------------------------------------------UACUGCAAUGUAAGCACUUCUU------------ 58 -2,-2 -----------------------------------------------UACUGCAAUGUAAGCACUUCUUA----------- 6 -2,-1 ------------------------------------------------ACUGCAAUGUAAGCACUUCU------------- 22 -1,-3 ------------------------------------------------ACUGCAAUGUAAGCACUUCUU------------ 58 -1,-2 ------------------------------------------------ACUGCAAUGUAAGCACUUCUUu----------- 3 -1,-2 ------------------------------------------------ACUGCAAUGUAAGCACUUCUUA----------- 30 -1,-1 ------------------------------------------------ACUGCAAUGUAAGCACUUCUUAC---------- 2 -1,0 -------------------------------------------------CUGCAAUGUAAGCACUUCUUA----------- 6 0,-1 >hsa-mir-106b MA:12-32;mi:52-73 Tumor ccugccggggcUAAAGUGCUGACAGUGCAGAUagugguccucuccgugcuaCCGCACUGUGGGUACUUGCUGCuccagcagg ----------CUAAAGUGCUGACAGUGCAG---------------------------------------------------- 2 -1,-2 ----------CUAAAGUGCUGACAGUGCAGA--------------------------------------------------- 36 -1,-1 ----------CUAAAGUGCUGACAGUGCAGAaa------------------------------------------------- 2 -1,-1 ----------CUAAAGUGCUGACAGUGCAGAU-------------------------------------------------- 294 -1,0 ----------CUAAAGUGCUGACAGUGCAGAUg------------------------------------------------- 2 -1,0 ----------CUAAAGUGCUGACAGUGCAGAUu------------------------------------------------- 6 -1,0 ----------CUAAAGUGCUGACAGUGCAGAUA------------------------------------------------- 183 -1,1 ----------CUAAAGUGCUGACAGUGCAGAUAa------------------------------------------------ 22 -1,1 ----------CUAAAGUGCUGACAGUGCAGAUAu------------------------------------------------ 10 -1,1 -----------UAAAGUGCUGACAGUGCA----------------------------------------------------- 463 0,-3 -----------UAAAGUGCUGACAGUGCAa---------------------------------------------------- 116 0,-3 -----------UAAAGUGCUGACAGUGCAaa--------------------------------------------------- 25 0,-3 -----------UAAAGUGCUGACAGUGCAau--------------------------------------------------- 2 0,-3 -----------UAAAGUGCUGACAGUGCAu---------------------------------------------------- 44 0,-3 -----------UAAAGUGCUGACAGUGCAG---------------------------------------------------- 2885 0,-2 -----------UAAAGUGCUGACAGUGCAGc--------------------------------------------------- 15 0,-2 -----------UAAAGUGCUGACAGUGCAGg--------------------------------------------------- 6 0,-2 -----------UAAAGUGCUGACAGUGCAGu--------------------------------------------------- 161 0,-2 -----------UAAAGUGCUGACAGUGCAGuu-------------------------------------------------- 76 0,-2 -----------UAAAGUGCUGACAGUGCAGA--------------------------------------------------- 13272 0,-1 -----------UAAAGUGCUGACAGUGCAGAa-------------------------------------------------- 1611 0,-1 -----------UAAAGUGCUGACAGUGCAGAaa------------------------------------------------- 1387 0,-1 -----------UAAAGUGCUGACAGUGCAGAau------------------------------------------------- 195 0,-1 -----------UAAAGUGCUGACAGUGCAGAc-------------------------------------------------- 87 0,-1 -----------UAAAGUGCUGACAGUGCAGAg-------------------------------------------------- 55 0,-1 -----------UAAAGUGCUGACAGUGCAGAU-------------------------------------------------- 72600 0,0 -----------UAAAGUGCUGACAGUGCAGAUc------------------------------------------------- 200 0,0 -----------UAAAGUGCUGACAGUGCAGAUg------------------------------------------------- 494 0,0 -----------UAAAGUGCUGACAGUGCAGAUu------------------------------------------------- 5045 0,0 -----------UAAAGUGCUGACAGUGCAGAUuu------------------------------------------------ 255 0,0 -----------UAAAGUGCUGACAGUGCAGAUA------------------------------------------------- 48048 0,1 -----------UAAAGUGCUGACAGUGCAGAUAa------------------------------------------------ 5385 0,1 -----------UAAAGUGCUGACAGUGCAGAUAaa----------------------------------------------- 137 0,1 -----------UAAAGUGCUGACAGUGCAGAUAau----------------------------------------------- 41 0,1 -----------UAAAGUGCUGACAGUGCAGAUAc------------------------------------------------ 41 0,1 -----------UAAAGUGCUGACAGUGCAGAUAu------------------------------------------------ 3834 0,1 -----------UAAAGUGCUGACAGUGCAGAUAuu----------------------------------------------- 33 0,1 -----------UAAAGUGCUGACAGUGCAGAUAG------------------------------------------------ 1411 0,2 -----------UAAAGUGCUGACAGUGCAGAUAGa----------------------------------------------- 42 0,2 -----------UAAAGUGCUGACAGUGCAGAUAGg----------------------------------------------- 2 0,2 -----------UAAAGUGCUGACAGUGCAGAUAGU----------------------------------------------- 269 0,3 ------------AAAGUGCUGACAGUGCAG---------------------------------------------------- 68 1,-2 ------------AAAGUGCUGACAGUGCAGu--------------------------------------------------- 2 1,-2 ------------AAAGUGCUGACAGUGCAGA--------------------------------------------------- 403 1,-1 ------------AAAGUGCUGACAGUGCAGAa-------------------------------------------------- 41 1,-1 ------------AAAGUGCUGACAGUGCAGAaa------------------------------------------------- 31 1,-1 ------------AAAGUGCUGACAGUGCAGAau------------------------------------------------- 4 1,-1 ------------AAAGUGCUGACAGUGCAGAU-------------------------------------------------- 2585 1,0 ------------AAAGUGCUGACAGUGCAGAUg------------------------------------------------- 8 1,0 ------------AAAGUGCUGACAGUGCAGAUu------------------------------------------------- 155 1,0 ------------AAAGUGCUGACAGUGCAGAUuu------------------------------------------------ 6 1,0 ------------AAAGUGCUGACAGUGCAGAUA------------------------------------------------- 1896 1,1 ------------AAAGUGCUGACAGUGCAGAUAa------------------------------------------------ 153 1,1 ------------AAAGUGCUGACAGUGCAGAUAaa----------------------------------------------- 4 1,1 ------------AAAGUGCUGACAGUGCAGAUAu------------------------------------------------ 92 1,1 ------------AAAGUGCUGACAGUGCAGAUAG------------------------------------------------ 42 1,2 ------------AAAGUGCUGACAGUGCAGAUAGU----------------------------------------------- 12 1,3 -------------AAGUGCUGACAGUGCAGA--------------------------------------------------- 24 2,-1 -------------AAGUGCUGACAGUGCAGAaa------------------------------------------------- 2 2,-1 -------------AAGUGCUGACAGUGCAGAU-------------------------------------------------- 228 2,0 -------------AAGUGCUGACAGUGCAGAUu------------------------------------------------- 4 2,0 -------------AAGUGCUGACAGUGCAGAUA------------------------------------------------- 127 2,1 -------------AAGUGCUGACAGUGCAGAUAa------------------------------------------------ 4 2,1 -------------AAGUGCUGACAGUGCAGAUAu------------------------------------------------ 4 2,1 -------------------------------------------------UACCGCACUGUGGGUACUU-------------- 2 -2,-5 -------------------------------------------------UACCGCACUGUGGGUACUUu------------- 2 -2,-5 -------------------------------------------------UACCGCACUGUGGGUACUUG------------- 20 -2,-4 -------------------------------------------------UACCGCACUGUGGGUACUUGa------------ 19 -2,-4 -------------------------------------------------UACCGCACUGUGGGUACUUGu------------ 6 -2,-4 -------------------------------------------------UACCGCACUGUGGGUACUUGuu----------- 6 -2,-4 -------------------------------------------------UACCGCACUGUGGGUACUUGC------------ 165 -2,-3 -------------------------------------------------UACCGCACUGUGGGUACUUGCU----------- 1449 -2,-2 -------------------------------------------------UACCGCACUGUGGGUACUUGCUa---------- 6 -2,-2 -------------------------------------------------UACCGCACUGUGGGUACUUGCUau--------- 2 -2,-2 -------------------------------------------------UACCGCACUGUGGGUACUUGCUu---------- 5 -2,-2 -------------------------------------------------UACCGCACUGUGGGUACUUGCUG---------- 4 -2,-1 -------------------------------------------------UACCGCACUGUGGGUACUUGCUGC--------- 4 -2,0 --------------------------------------------------ACCGCACUGUGGGUACUUG------------- 2 -1,-4 --------------------------------------------------ACCGCACUGUGGGUACUUGC------------ 4 -1,-3 --------------------------------------------------ACCGCACUGUGGGUACUUGCU----------- 184 -1,-2 --------------------------------------------------ACCGCACUGUGGGUACUUGCUG---------- 28 -1,-1 --------------------------------------------------ACCGCACUGUGGGUACUUGCUGu--------- 6 -1,-1 --------------------------------------------------ACCGCACUGUGGGUACUUGCUGC--------- 5 -1,0 ---------------------------------------------------CCGCACUGUGGGUACUUG------------- 32 0,-4 ---------------------------------------------------CCGCACUGUGGGUACUUGa------------ 7 0,-4 ---------------------------------------------------CCGCACUGUGGGUACUUGu------------ 6 0,-4 ---------------------------------------------------CCGCACUGUGGGUACUUGC------------ 119 0,-3 ---------------------------------------------------CCGCACUGUGGGUACUUGCU----------- 1962 0,-2 ---------------------------------------------------CCGCACUGUGGGUACUUGCUa---------- 19 0,-2 ---------------------------------------------------CCGCACUGUGGGUACUUGCUau--------- 2 0,-2 ---------------------------------------------------CCGCACUGUGGGUACUUGCUu---------- 23 0,-2 ---------------------------------------------------CCGCACUGUGGGUACUUGCUG---------- 934 0,-1 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGa--------- 176 0,-1 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGaa-------- 10 0,-1 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGau-------- 2 0,-1 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGu--------- 576 0,-1 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGuu-------- 12 0,-1 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGC--------- 699 0,0 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGCa-------- 42 0,0 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGCau------- 11 0,0 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGCU-------- 52 0,1 ---------------------------------------------------CCGCACUGUGGGUACUUGCUGCUu------- 4 0,1 ----------------------------------------------------CGCACUGUGGGUACUUGC------------ 2 1,-3 ----------------------------------------------------CGCACUGUGGGUACUUGCU----------- 52 1,-2 ----------------------------------------------------CGCACUGUGGGUACUUGCUG---------- 10 1,-1 ----------------------------------------------------CGCACUGUGGGUACUUGCUGu--------- 13 1,-1 ----------------------------------------------------CGCACUGUGGGUACUUGCUGC--------- 18 1,0 >hsa-mir-107 3pM:50-72 Tumor cucucugcuuucagcuucuuuacaguguugccuuguggcauggaguucaAGCAGCAUUGUACAGGGCUAUCAaagcacaga ------------AGCUUCUUUACAGUGUUGCCUUGU--------------------------------------------- 2 ------------------------------------------------AAGCAGCAUUGUACAGGGCUAU----------- 5 -1,-2 -------------------------------------------------AGCAGCAUUGUACAGGGC-------------- 1068 0,-5 -------------------------------------------------AGCAGCAUUGUACAGGGCa------------- 4 0,-5 -------------------------------------------------AGCAGCAUUGUACAGGGCaa------------ 18 0,-5 -------------------------------------------------AGCAGCAUUGUACAGGGCc------------- 2 0,-5 -------------------------------------------------AGCAGCAUUGUACAGGGCU------------- 6141 0,-4 -------------------------------------------------AGCAGCAUUGUACAGGGCUc------------ 2 0,-4 -------------------------------------------------AGCAGCAUUGUACAGGGCUg------------ 7 0,-4 -------------------------------------------------AGCAGCAUUGUACAGGGCUu------------ 939 0,-4 -------------------------------------------------AGCAGCAUUGUACAGGGCUuu----------- 554 0,-4 -------------------------------------------------AGCAGCAUUGUACAGGGCUA------------ 5946 0,-3 -------------------------------------------------AGCAGCAUUGUACAGGGCUAa----------- 1967 0,-3 -------------------------------------------------AGCAGCAUUGUACAGGGCUAaa---------- 952 0,-3 -------------------------------------------------AGCAGCAUUGUACAGGGCUAau---------- 350 0,-3 -------------------------------------------------AGCAGCAUUGUACAGGGCUAc----------- 78 0,-3 -------------------------------------------------AGCAGCAUUGUACAGGGCUAg----------- 110 0,-3 -------------------------------------------------AGCAGCAUUGUACAGGGCUAU----------- 61415 0,-2 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUa---------- 4219 0,-2 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUaa--------- 4922 0,-2 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUau--------- 1467 0,-2 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUu---------- 7060 0,-2 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUuu--------- 1279 0,-2 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUC---------- 2585 0,-1 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUCc--------- 13 0,-1 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUCg--------- 19 0,-1 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUCu--------- 679 0,-1 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUCuu-------- 2 0,-1 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUCA--------- 3053 0,0 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUCAg-------- 2 0,0 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUCAu-------- 84 0,0 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUCAuu------- 2 0,0 -------------------------------------------------AGCAGCAUUGUACAGGGCUAUCAA-------- 58 0,1 --------------------------------------------------GCAGCAUUGUACAGGGCU------------- 94 1,-4 --------------------------------------------------GCAGCAUUGUACAGGGCUc------------ 2 1,-4 --------------------------------------------------GCAGCAUUGUACAGGGCUu------------ 5 1,-4 --------------------------------------------------GCAGCAUUGUACAGGGCUuu----------- 6 1,-4 --------------------------------------------------GCAGCAUUGUACAGGGCUA------------ 56 1,-3 --------------------------------------------------GCAGCAUUGUACAGGGCUAa----------- 10 1,-3 --------------------------------------------------GCAGCAUUGUACAGGGCUAau---------- 2 1,-3 --------------------------------------------------GCAGCAUUGUACAGGGCUAc----------- 2 1,-3 --------------------------------------------------GCAGCAUUGUACAGGGCUAU----------- 1010 1,-2 --------------------------------------------------GCAGCAUUGUACAGGGCUAUa---------- 41 1,-2 --------------------------------------------------GCAGCAUUGUACAGGGCUAUaa--------- 56 1,-2 --------------------------------------------------GCAGCAUUGUACAGGGCUAUau--------- 2 1,-2 --------------------------------------------------GCAGCAUUGUACAGGGCUAUu---------- 84 1,-2 --------------------------------------------------GCAGCAUUGUACAGGGCUAUuu--------- 6 1,-2 --------------------------------------------------GCAGCAUUGUACAGGGCUAUC---------- 12 1,-1 --------------------------------------------------GCAGCAUUGUACAGGGCUAUCu--------- 2 1,-1 --------------------------------------------------GCAGCAUUGUACAGGGCUAUCA--------- 25 1,0 ---------------------------------------------------CAGCAUUGUACAGGGCUA------------ 6 2,-3 ---------------------------------------------------CAGCAUUGUACAGGGCUAU----------- 58 2,-2 ---------------------------------------------------CAGCAUUGUACAGGGCUAUa---------- 2 2,-2 ---------------------------------------------------CAGCAUUGUACAGGGCUAUaa--------- 2 2,-2 ---------------------------------------------------CAGCAUUGUACAGGGCUAUu---------- 2 2,-2 ---------------------------------------------------CAGCAUUGUACAGGGCUAUCA--------- 2 2,0 >hsa-mir-10a MA:22-44;mi:63-84 Tumor gaucugucugucuucuguauaUACCCUGUAGAUCCGAAUUUGUGuaaggaauuuuguggucaCAAAUUCGUAUCUAGGGGAAUAuguaguugacauaaacacuccgcucu --------------------AUACCCUGUAGAUCCGAAUUU--------------------------------------------------------------------- 14 -1,-3 --------------------AUACCCUGUAGAUCCGAAUUUG-------------------------------------------------------------------- 81 -1,-2 --------------------AUACCCUGUAGAUCCGAAUUUGa------------------------------------------------------------------- 4 -1,-2 --------------------AUACCCUGUAGAUCCGAAUUUGU------------------------------------------------------------------- 313 -1,-1 --------------------AUACCCUGUAGAUCCGAAUUUGUG------------------------------------------------------------------ 12 -1,0 ---------------------UACCCUGUAGAUCCGAAU----------------------------------------------------------------------- 16 0,-5 ---------------------UACCCUGUAGAUCCGAAUa---------------------------------------------------------------------- 2 0,-5 ---------------------UACCCUGUAGAUCCGAAUU---------------------------------------------------------------------- 47 0,-4 ---------------------UACCCUGUAGAUCCGAAUUU--------------------------------------------------------------------- 268 0,-3 ---------------------UACCCUGUAGAUCCGAAUUUau------------------------------------------------------------------- 19 0,-3 ---------------------UACCCUGUAGAUCCGAAUUUu-------------------------------------------------------------------- 2 0,-3 ---------------------UACCCUGUAGAUCCGAAUUUuu------------------------------------------------------------------- 52 0,-3 ---------------------UACCCUGUAGAUCCGAAUUUG-------------------------------------------------------------------- 1629 0,-2 ---------------------UACCCUGUAGAUCCGAAUUUGa------------------------------------------------------------------- 127 0,-2 ---------------------UACCCUGUAGAUCCGAAUUUGaa------------------------------------------------------------------ 2 0,-2 ---------------------UACCCUGUAGAUCCGAAUUUGc------------------------------------------------------------------- 27 0,-2 ---------------------UACCCUGUAGAUCCGAAUUUGg------------------------------------------------------------------- 7 0,-2 ---------------------UACCCUGUAGAUCCGAAUUUGU------------------------------------------------------------------- 21063 0,-1 ---------------------UACCCUGUAGAUCCGAAUUUGUa------------------------------------------------------------------ 151 0,-1 ---------------------UACCCUGUAGAUCCGAAUUUGUaa----------------------------------------------------------------- 6 0,-1 ---------------------UACCCUGUAGAUCCGAAUUUGUau----------------------------------------------------------------- 4 0,-1 ---------------------UACCCUGUAGAUCCGAAUUUGUu------------------------------------------------------------------ 62 0,-1 ---------------------UACCCUGUAGAUCCGAAUUUGUG------------------------------------------------------------------ 4822 0,0 ---------------------UACCCUGUAGAUCCGAAUUUGUGa----------------------------------------------------------------- 957 0,0 ---------------------UACCCUGUAGAUCCGAAUUUGUGaa---------------------------------------------------------------- 5 0,0 ---------------------UACCCUGUAGAUCCGAAUUUGUGc----------------------------------------------------------------- 2 0,0 ---------------------UACCCUGUAGAUCCGAAUUUGUGU----------------------------------------------------------------- 784 0,1 ----------------------ACCCUGUAGAUCCGAAUU---------------------------------------------------------------------- 25 1,-4 ----------------------ACCCUGUAGAUCCGAAUUU--------------------------------------------------------------------- 217 1,-3 ----------------------ACCCUGUAGAUCCGAAUUUau------------------------------------------------------------------- 4 1,-3 ----------------------ACCCUGUAGAUCCGAAUUUuu------------------------------------------------------------------- 23 1,-3 ----------------------ACCCUGUAGAUCCGAAUUUG-------------------------------------------------------------------- 797 1,-2 ----------------------ACCCUGUAGAUCCGAAUUUGa------------------------------------------------------------------- 57 1,-2 ----------------------ACCCUGUAGAUCCGAAUUUGaa------------------------------------------------------------------ 4 1,-2 ----------------------ACCCUGUAGAUCCGAAUUUGc------------------------------------------------------------------- 10 1,-2 ----------------------ACCCUGUAGAUCCGAAUUUGg------------------------------------------------------------------- 5 1,-2 ----------------------ACCCUGUAGAUCCGAAUUUGU------------------------------------------------------------------- 10041 1,-1 ----------------------ACCCUGUAGAUCCGAAUUUGUa------------------------------------------------------------------ 59 1,-1 ----------------------ACCCUGUAGAUCCGAAUUUGUaa----------------------------------------------------------------- 21 1,-1 ----------------------ACCCUGUAGAUCCGAAUUUGUau----------------------------------------------------------------- 6 1,-1 ----------------------ACCCUGUAGAUCCGAAUUUGUc------------------------------------------------------------------ 4 1,-1 ----------------------ACCCUGUAGAUCCGAAUUUGUu------------------------------------------------------------------ 48 1,-1 ----------------------ACCCUGUAGAUCCGAAUUUGUG------------------------------------------------------------------ 9074 1,0 ----------------------ACCCUGUAGAUCCGAAUUUGUGa----------------------------------------------------------------- 4322 1,0 ----------------------ACCCUGUAGAUCCGAAUUUGUGaa---------------------------------------------------------------- 62 1,0 ----------------------ACCCUGUAGAUCCGAAUUUGUGau---------------------------------------------------------------- 2 1,0 ----------------------ACCCUGUAGAUCCGAAUUUGUGc----------------------------------------------------------------- 9 1,0 ----------------------ACCCUGUAGAUCCGAAUUUGUGg----------------------------------------------------------------- 11 1,0 ----------------------ACCCUGUAGAUCCGAAUUUGUGU----------------------------------------------------------------- 2210 1,1 ----------------------ACCCUGUAGAUCCGAAUUUGUGUA---------------------------------------------------------------- 7 1,2 -----------------------CCCUGUAGAUCCGAAUUUuu------------------------------------------------------------------- 4 2,-3 -----------------------CCCUGUAGAUCCGAAUUUG-------------------------------------------------------------------- 3 2,-2 -----------------------CCCUGUAGAUCCGAAUUUGU------------------------------------------------------------------- 94 2,-1 -----------------------CCCUGUAGAUCCGAAUUUGUG------------------------------------------------------------------ 97 2,0 -----------------------CCCUGUAGAUCCGAAUUUGUGa----------------------------------------------------------------- 36 2,0 -----------------------CCCUGUAGAUCCGAAUUUGUGU----------------------------------------------------------------- 27 2,1 -------------------------------------------------------------ACAAAUUCGUAUCUAGGGGAAU--------------------------- 34 -1,-1 --------------------------------------------------------------CAAAUUCGUAUCUAGGGGA----------------------------- 3 0,-3 --------------------------------------------------------------CAAAUUCGUAUCUAGGGGAA---------------------------- 71 0,-2 --------------------------------------------------------------CAAAUUCGUAUCUAGGGGAAa--------------------------- 16 0,-2 --------------------------------------------------------------CAAAUUCGUAUCUAGGGGAAaa-------------------------- 3 0,-2 --------------------------------------------------------------CAAAUUCGUAUCUAGGGGAAU--------------------------- 1108 0,-1 --------------------------------------------------------------CAAAUUCGUAUCUAGGGGAAUu-------------------------- 42 0,-1 --------------------------------------------------------------CAAAUUCGUAUCUAGGGGAAUA-------------------------- 13 0,0 --------------------------------------------------------------CAAAUUCGUAUCUAGGGGAAUAa------------------------- 6 0,0 ---------------------------------------------------------------AAAUUCGUAUCUAGGGGAA---------------------------- 5 1,-2 ---------------------------------------------------------------AAAUUCGUAUCUAGGGGAAa--------------------------- 2 1,-2 ---------------------------------------------------------------AAAUUCGUAUCUAGGGGAAaa-------------------------- 2 1,-2 ---------------------------------------------------------------AAAUUCGUAUCUAGGGGAAU--------------------------- 235 1,-1 ---------------------------------------------------------------AAAUUCGUAUCUAGGGGAAUu-------------------------- 2 1,-1 ---------------------------------------------------------------AAAUUCGUAUCUAGGGGAAUA-------------------------- 42 1,0 ---------------------------------------------------------------AAAUUCGUAUCUAGGGGAAUAa------------------------- 3 1,0 ---------------------------------------------------------------AAAUUCGUAUCUAGGGGAAUAU------------------------- 15 1,1 ----------------------------------------------------------------AAUUCGUAUCUAGGGGAAU--------------------------- 2 2,-1 ----------------------------------------------------------------AAUUCGUAUCUAGGGGAAUAU------------------------- 4 2,1 >hsa-mir-10b MA:27-49;mi:66-87 Tumor ccagagguuguaacguugucuauauaUACCCUGUAGAACCGAAUUUGUGugguauccguauagucACAGAUUCGAUUCUAGGGGAAUauauggucgaugcaaaaacuuca --------------------------UACCCUGUAGAACCGAAU------------------------------------------------------------------ 49 0,-5 --------------------------UACCCUGUAGAACCGAAUaa---------------------------------------------------------------- 6 0,-5 --------------------------UACCCUGUAGAACCGAAUU----------------------------------------------------------------- 91 0,-4 --------------------------UACCCUGUAGAACCGAAUUa---------------------------------------------------------------- 4 0,-4 --------------------------UACCCUGUAGAACCGAAUUg---------------------------------------------------------------- 2 0,-4 --------------------------UACCCUGUAGAACCGAAUUU---------------------------------------------------------------- 589 0,-3 --------------------------UACCCUGUAGAACCGAAUUUau-------------------------------------------------------------- 49 0,-3 --------------------------UACCCUGUAGAACCGAAUUUuu-------------------------------------------------------------- 75 0,-3 --------------------------UACCCUGUAGAACCGAAUUUG--------------------------------------------------------------- 3863 0,-2 --------------------------UACCCUGUAGAACCGAAUUUGa-------------------------------------------------------------- 494 0,-2 --------------------------UACCCUGUAGAACCGAAUUUGaa------------------------------------------------------------- 5 0,-2 --------------------------UACCCUGUAGAACCGAAUUUGc-------------------------------------------------------------- 38 0,-2 --------------------------UACCCUGUAGAACCGAAUUUGg-------------------------------------------------------------- 25 0,-2 --------------------------UACCCUGUAGAACCGAAUUUGU-------------------------------------------------------------- 39465 0,-1 --------------------------UACCCUGUAGAACCGAAUUUGUa------------------------------------------------------------- 286 0,-1 --------------------------UACCCUGUAGAACCGAAUUUGUaa------------------------------------------------------------ 22 0,-1 --------------------------UACCCUGUAGAACCGAAUUUGUu------------------------------------------------------------- 94 0,-1 --------------------------UACCCUGUAGAACCGAAUUUGUG------------------------------------------------------------- 5454 0,0 --------------------------UACCCUGUAGAACCGAAUUUGUGa------------------------------------------------------------ 948 0,0 --------------------------UACCCUGUAGAACCGAAUUUGUGaa----------------------------------------------------------- 7 0,0 --------------------------UACCCUGUAGAACCGAAUUUGUGc------------------------------------------------------------ 2 0,0 --------------------------UACCCUGUAGAACCGAAUUUGUGg------------------------------------------------------------ 2 0,0 --------------------------UACCCUGUAGAACCGAAUUUGUGU------------------------------------------------------------ 698 0,1 ---------------------------ACCCUGUAGAACCGAAUU----------------------------------------------------------------- 17 1,-4 ---------------------------ACCCUGUAGAACCGAAUUU---------------------------------------------------------------- 138 1,-3 ---------------------------ACCCUGUAGAACCGAAUUUau-------------------------------------------------------------- 5 1,-3 ---------------------------ACCCUGUAGAACCGAAUUUuu-------------------------------------------------------------- 6 1,-3 ---------------------------ACCCUGUAGAACCGAAUUUG--------------------------------------------------------------- 646 1,-2 ---------------------------ACCCUGUAGAACCGAAUUUGa-------------------------------------------------------------- 39 1,-2 ---------------------------ACCCUGUAGAACCGAAUUUGc-------------------------------------------------------------- 7 1,-2 ---------------------------ACCCUGUAGAACCGAAUUUGg-------------------------------------------------------------- 5 1,-2 ---------------------------ACCCUGUAGAACCGAAUUUGU-------------------------------------------------------------- 5826 1,-1 ---------------------------ACCCUGUAGAACCGAAUUUGUa------------------------------------------------------------- 38 1,-1 ---------------------------ACCCUGUAGAACCGAAUUUGUau------------------------------------------------------------ 5 1,-1 ---------------------------ACCCUGUAGAACCGAAUUUGUu------------------------------------------------------------- 10 1,-1 ---------------------------ACCCUGUAGAACCGAAUUUGUuu------------------------------------------------------------ 2 1,-1 ---------------------------ACCCUGUAGAACCGAAUUUGUG------------------------------------------------------------- 4799 1,0 ---------------------------ACCCUGUAGAACCGAAUUUGUGa------------------------------------------------------------ 1891 1,0 ---------------------------ACCCUGUAGAACCGAAUUUGUGaa----------------------------------------------------------- 18 1,0 ---------------------------ACCCUGUAGAACCGAAUUUGUGc------------------------------------------------------------ 7 1,0 ---------------------------ACCCUGUAGAACCGAAUUUGUGU------------------------------------------------------------ 2943 1,1 ----------------------------CCCUGUAGAACCGAAUUUGU-------------------------------------------------------------- 44 2,-1 ----------------------------CCCUGUAGAACCGAAUUUGUG------------------------------------------------------------- 16 2,0 ----------------------------CCCUGUAGAACCGAAUUUGUGa------------------------------------------------------------ 5 2,0 ----------------------------CCCUGUAGAACCGAAUUUGUGU------------------------------------------------------------ 15 2,1 ----------------------------------------------------------------CACAGAUUCGAUUCUAGGGGAAU----------------------- 2 -1,0 -----------------------------------------------------------------ACAGAUUCGAUUCUAGGGGA------------------------- 4 0,-2 -----------------------------------------------------------------ACAGAUUCGAUUCUAGGGGAA------------------------ 28 0,-1 -----------------------------------------------------------------ACAGAUUCGAUUCUAGGGGAAa----------------------- 2 0,-1 -----------------------------------------------------------------ACAGAUUCGAUUCUAGGGGAAU----------------------- 438 0,0 -----------------------------------------------------------------ACAGAUUCGAUUCUAGGGGAAUA---------------------- 2 0,1 ------------------------------------------------------------------CAGAUUCGAUUCUAGGGGA------------------------- 3 1,-2 ------------------------------------------------------------------CAGAUUCGAUUCUAGGGGAA------------------------ 21 1,-1 ------------------------------------------------------------------CAGAUUCGAUUCUAGGGGAAa----------------------- 4 1,-1 ------------------------------------------------------------------CAGAUUCGAUUCUAGGGGAAU----------------------- 518 1,0 ------------------------------------------------------------------CAGAUUCGAUUCUAGGGGAAUu---------------------- 7 1,0 ------------------------------------------------------------------CAGAUUCGAUUCUAGGGGAAUA---------------------- 14 1,1 -------------------------------------------------------------------AGAUUCGAUUCUAGGGGAA------------------------ 16 2,-1 -------------------------------------------------------------------AGAUUCGAUUCUAGGGGAAa----------------------- 6 2,-1 -------------------------------------------------------------------AGAUUCGAUUCUAGGGGAAU----------------------- 585 2,0 -------------------------------------------------------------------AGAUUCGAUUCUAGGGGAAUu---------------------- 7 2,0 -------------------------------------------------------------------AGAUUCGAUUCUAGGGGAAUA---------------------- 80 2,1 -------------------------------------------------------------------AGAUUCGAUUCUAGGGGAAUAa--------------------- 8 2,1 -------------------------------------------------------------------AGAUUCGAUUCUAGGGGAAUAU--------------------- 18 2,2 >hsa-mir-1179 5pM:15-35 Tumor ggcuggaaaggaagAAGCAUUCUUUCAUUGGUUGGuguguauugccuugucaaccaauaagaggaugccauuuauccuuuucugacuagcu --------------AAGCAUUCUUUCAUUGGUUGGU------------------------------------------------------- 10 0,1 >hsa-mir-1180 3pM:41-62 Tumor gcugcuggacccacccggccgggaauagugcuccugguugUUUCCGGCUCGCGUGGGUGUGUcggcggc ----------------------------------------UUUCCGGCUCGCGUGGGUGU--------- 70 0,-2 ----------------------------------------UUUCCGGCUCGCGUGGGUGUG-------- 3 0,-1 ----------------------------------------UUUCCGGCUCGCGUGGGUGUGU------- 147 0,0 ----------------------------------------UUUCCGGCUCGCGUGGGUGUGUu------ 5 0,0 ----------------------------------------UUUCCGGCUCGCGUGGGUGUGUuu----- 4 0,0 -----------------------------------------UUCCGGCUCGCGUGGGUGUGU------- 2 1,0 >hsa-mir-1185-1 5pM:15-35 Tumor uuugguacuugaagAGAGGAUACCCUUUGUAUGUUcacuugauuaauggcgaauauacagggggagacucuuauuugcguaucaaa --------------AGAGGAUACCCUUUGUAUGU---------------------------------------------------- 11 0,-1 --------------AGAGGAUACCCUUUGUAUGUU--------------------------------------------------- 68 0,0 --------------AGAGGAUACCCUUUGUAUGUUC-------------------------------------------------- 322 0,1 ---------------------------------------------------AAUAUACAGGGGGAGACUCUUA------------- 2 ----------------------------------------------------AUAUACAGGGGGAGACUCU--------------- 4 ----------------------------------------------------AUAUACAGGGGGAGACUCUU-------------- 45 ----------------------------------------------------AUAUACAGGGGGAGACUCUUu------------- 2 ----------------------------------------------------AUAUACAGGGGGAGACUCUUA------------- 62 ----------------------------------------------------AUAUACAGGGGGAGACUCUUAa------------ 12 ----------------------------------------------------AUAUACAGGGGGAGACUCUUAaa----------- 4 ----------------------------------------------------AUAUACAGGGGGAGACUCUUAU------------ 147 ----------------------------------------------------AUAUACAGGGGGAGACUCUUAUa----------- 2 -----------------------------------------------------UAUACAGGGGGAGACUCUUAUU----------- 2 >hsa-mir-1185-2 5pM:15-35 Tumor uuugguacuuaaagAGAGGAUACCCUUUGUAUGUUcacuugauuaauggcgaauauacagggggagacucucauuugcguaucaaa --------------AGAGGAUACCCUUUGUAUGU---------------------------------------------------- 11 0,-1 --------------AGAGGAUACCCUUUGUAUGUU--------------------------------------------------- 68 0,0 --------------AGAGGAUACCCUUUGUAUGUUC-------------------------------------------------- 322 0,1 ----------------------------------------------------AUAUACAGGGGGAGACUCU--------------- 4 ----------------------------------------------------AUAUACAGGGGGAGACUCUCA------------- 14 ----------------------------------------------------AUAUACAGGGGGAGACUCUCAU------------ 6 >hsa-mir-1197 3pM:57-77 Tumor acuuccugguauuugaagaugcgguugaccaugguguguacgcuuuauuugugacgUAGGACACAUGGUCUACUUCUucucaauauca --------------------------------------------------------UAGGACACAUGGUCUACUUCU----------- 12 0,0 >hsa-mir-1224 5p:1-19;3p:65-85 Tumor GUGAGGACUCGGGAGGUGGaggguggugccgccggggccgggcgcuguuucagcucgcuucuccCCCCACCUCCUCUCUCCUCAG GUGAGGACUCGGGAGGUGGAG---------------------------------------------------------------- 2 0,2 >hsa-mir-1226 mi:1-26;MA:54-75 Tumor GUGAGGGCAUGCAGGCCUGGAUGGGGcagcugggaugguccaaaaggguggccUCACCAGCCCUGUGUUCCCUAG -----------------------------------------------------UCACCAGCCCUGUGUUCCCUAG 5 0,0 -----------------------------------------------------UCACCAGCCCUGUGUUCCCUAGa 17 0,0 -----------------------------------------------------UCACCAGCCCUGUGUUCCCUAGu 30 0,0 ------------------------------------------------------CACCAGCCCUGUGUUCCCUAGu 2 1,0 >hsa-mir-1227 3pM:69-88 Tumor guggggccaggcgguggugggcacugcuggggugggcacagcagccaugcagagcgggcauuugacccCGUGCCACCCUUUUCCCCAG --------------------------------------------------------------------CGUGCCACCCUUUUCCCCAGa 2 0,0 --------------------------------------------------------------------CGUGCCACCCUUUUCCCCAGu 2 0,0 >hsa-mir-1228 mi:1-21;MA:52-71 Tumor GUGGGCGGGGGCAGGUGUGUGgugggugguggccugcggugagcagggcccUCACACCUGCCUCGCCCCCCag GUGGGCGGGGGCAGGUGUGUGG--------------------------------------------------- 4 0,1 ---------------------------------------------------UCACACCUGCCUCGCCCCCCA- 3 0,1 >hsa-mir-1229 3pM:47-69 Tumor guggguaggguuugggggagagcgugggcugggguucagggacaccCUCUCACCACUGCCCUCCCACAG ----------------------------------------------CUCUCACCACUGCCCUCCCACAGu 4 0,0 >hsa-mir-124-1 mi:14-35;MA:53-72 Tumor aggccucucucucCGUGUUCACAGCGGACCUUGAUuuaaauguccauacaauUAAGGCACGCGGUGAAUGCCaagaauggggcug -------------CGUGUUCACAGCGGACCUUGA--------------------------------------------------- 48 0,-1 -------------CGUGUUCACAGCGGACCUUGAU-------------------------------------------------- 6 0,0 -------------CGUGUUCACAGCGGACCUUGAUU------------------------------------------------- 2 0,1 --------------GUGUUCACAGCGGACCUUGA--------------------------------------------------- 3 1,-1 ---------------------------------------------------UUAAGGCACGCGGUGAAU---------------- 11 -1,-3 ---------------------------------------------------UUAAGGCACGCGGUGAAUu--------------- 2 -1,-3 ---------------------------------------------------UUAAGGCACGCGGUGAAUG--------------- 45 -1,-2 ---------------------------------------------------UUAAGGCACGCGGUGAAUGa-------------- 18 -1,-2 ---------------------------------------------------UUAAGGCACGCGGUGAAUGu-------------- 8 -1,-2 ---------------------------------------------------UUAAGGCACGCGGUGAAUGC-------------- 82 -1,-1 ---------------------------------------------------UUAAGGCACGCGGUGAAUGCa------------- 9 -1,-1 ---------------------------------------------------UUAAGGCACGCGGUGAAUGCu------------- 6 -1,-1 ---------------------------------------------------UUAAGGCACGCGGUGAAUGCC------------- 201 -1,0 ---------------------------------------------------UUAAGGCACGCGGUGAAUGCCu------------ 6 -1,0 ---------------------------------------------------UUAAGGCACGCGGUGAAUGCCA------------ 24 -1,1 ---------------------------------------------------UUAAGGCACGCGGUGAAUGCCAuu---------- 2 -1,1 ----------------------------------------------------UAAGGCACGCGGUGAAUG--------------- 72 0,-2 ----------------------------------------------------UAAGGCACGCGGUGAAUGa-------------- 38 0,-2 ----------------------------------------------------UAAGGCACGCGGUGAAUGu-------------- 29 0,-2 ----------------------------------------------------UAAGGCACGCGGUGAAUGC-------------- 185 0,-1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCa------------- 12 0,-1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCaa------------ 2 0,-1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCu------------- 7 0,-1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCC------------- 513 0,0 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCu------------ 17 0,0 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCA------------ 255 0,1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAu----------- 11 0,1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAuu---------- 10 0,1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAA----------- 19 0,2 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAAa---------- 15 0,2 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAAu---------- 21 0,2 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAAuu--------- 2 0,2 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAAG---------- 11 0,3 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAAGA--------- 2 0,4 -----------------------------------------------------AAGGCACGCGGUGAAUGC-------------- 5 1,-1 -----------------------------------------------------AAGGCACGCGGUGAAUGCC------------- 11 1,0 -----------------------------------------------------AAGGCACGCGGUGAAUGCCA------------ 13 1,1 -----------------------------------------------------AAGGCACGCGGUGAAUGCCAA----------- 2 1,2 ------------------------------------------------------AGGCACGCGGUGAAUGCCA------------ 2 2,1 >hsa-mir-124-2 mi:25-46;MA:62-81 Tumor aucaagauuagaggcucugcucucCGUGUUCACAGCGGACCUUGAUuuaaugucauacaauUAAGGCACGCGGUGAAUGCCaagagcggagccuacggcugcacuugaa ------------------------CGUGUUCACAGCGGACCUUGA---------------------------------------------------------------- 48 0,-1 ------------------------CGUGUUCACAGCGGACCUUGAU--------------------------------------------------------------- 6 0,0 ------------------------CGUGUUCACAGCGGACCUUGAUU-------------------------------------------------------------- 2 0,1 -------------------------GUGUUCACAGCGGACCUUGA---------------------------------------------------------------- 3 1,-1 ------------------------------------------------------------UUAAGGCACGCGGUGAAU------------------------------- 11 -1,-3 ------------------------------------------------------------UUAAGGCACGCGGUGAAUu------------------------------ 2 -1,-3 ------------------------------------------------------------UUAAGGCACGCGGUGAAUG------------------------------ 45 -1,-2 ------------------------------------------------------------UUAAGGCACGCGGUGAAUGa----------------------------- 18 -1,-2 ------------------------------------------------------------UUAAGGCACGCGGUGAAUGu----------------------------- 8 -1,-2 ------------------------------------------------------------UUAAGGCACGCGGUGAAUGC----------------------------- 82 -1,-1 ------------------------------------------------------------UUAAGGCACGCGGUGAAUGCa---------------------------- 9 -1,-1 ------------------------------------------------------------UUAAGGCACGCGGUGAAUGCu---------------------------- 6 -1,-1 ------------------------------------------------------------UUAAGGCACGCGGUGAAUGCC---------------------------- 201 -1,0 ------------------------------------------------------------UUAAGGCACGCGGUGAAUGCCu--------------------------- 6 -1,0 ------------------------------------------------------------UUAAGGCACGCGGUGAAUGCCA--------------------------- 24 -1,1 ------------------------------------------------------------UUAAGGCACGCGGUGAAUGCCAuu------------------------- 2 -1,1 -------------------------------------------------------------UAAGGCACGCGGUGAAUG------------------------------ 72 0,-2 -------------------------------------------------------------UAAGGCACGCGGUGAAUGa----------------------------- 38 0,-2 -------------------------------------------------------------UAAGGCACGCGGUGAAUGu----------------------------- 29 0,-2 -------------------------------------------------------------UAAGGCACGCGGUGAAUGC----------------------------- 185 0,-1 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCa---------------------------- 12 0,-1 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCaa--------------------------- 2 0,-1 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCu---------------------------- 7 0,-1 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCC---------------------------- 513 0,0 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCCu--------------------------- 17 0,0 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCCA--------------------------- 255 0,1 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCCAu-------------------------- 11 0,1 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCCAuu------------------------- 10 0,1 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCCAA-------------------------- 19 0,2 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCCAAa------------------------- 15 0,2 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCCAAu------------------------- 21 0,2 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCCAAuu------------------------ 2 0,2 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCCAAG------------------------- 11 0,3 -------------------------------------------------------------UAAGGCACGCGGUGAAUGCCAAGA------------------------ 2 0,4 --------------------------------------------------------------AAGGCACGCGGUGAAUGC----------------------------- 5 1,-1 --------------------------------------------------------------AAGGCACGCGGUGAAUGCC---------------------------- 11 1,0 --------------------------------------------------------------AAGGCACGCGGUGAAUGCCA--------------------------- 13 1,1 --------------------------------------------------------------AAGGCACGCGGUGAAUGCCAA-------------------------- 2 1,2 ---------------------------------------------------------------AGGCACGCGGUGAAUGCCA--------------------------- 2 2,1 >hsa-mir-124-3 mi:15-36;MA:53-72 Tumor ugagggccccucugCGUGUUCACAGCGGACCUUGAUuuaaugucuauacaauUAAGGCACGCGGUGAAUGCCaagagaggcgccucc --------------CGUGUUCACAGCGGACCUUGA---------------------------------------------------- 48 0,-1 --------------CGUGUUCACAGCGGACCUUGAU--------------------------------------------------- 6 0,0 --------------CGUGUUCACAGCGGACCUUGAUU-------------------------------------------------- 2 0,1 ---------------GUGUUCACAGCGGACCUUGA---------------------------------------------------- 3 1,-1 ---------------------------------------------------UUAAGGCACGCGGUGAAU------------------ 11 -1,-3 ---------------------------------------------------UUAAGGCACGCGGUGAAUu----------------- 2 -1,-3 ---------------------------------------------------UUAAGGCACGCGGUGAAUG----------------- 45 -1,-2 ---------------------------------------------------UUAAGGCACGCGGUGAAUGa---------------- 18 -1,-2 ---------------------------------------------------UUAAGGCACGCGGUGAAUGu---------------- 8 -1,-2 ---------------------------------------------------UUAAGGCACGCGGUGAAUGC---------------- 82 -1,-1 ---------------------------------------------------UUAAGGCACGCGGUGAAUGCa--------------- 9 -1,-1 ---------------------------------------------------UUAAGGCACGCGGUGAAUGCu--------------- 6 -1,-1 ---------------------------------------------------UUAAGGCACGCGGUGAAUGCC--------------- 201 -1,0 ---------------------------------------------------UUAAGGCACGCGGUGAAUGCCu-------------- 6 -1,0 ---------------------------------------------------UUAAGGCACGCGGUGAAUGCCA-------------- 24 -1,1 ---------------------------------------------------UUAAGGCACGCGGUGAAUGCCAuu------------ 2 -1,1 ----------------------------------------------------UAAGGCACGCGGUGAAUG----------------- 72 0,-2 ----------------------------------------------------UAAGGCACGCGGUGAAUGa---------------- 38 0,-2 ----------------------------------------------------UAAGGCACGCGGUGAAUGu---------------- 29 0,-2 ----------------------------------------------------UAAGGCACGCGGUGAAUGC---------------- 185 0,-1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCa--------------- 12 0,-1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCaa-------------- 2 0,-1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCu--------------- 7 0,-1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCC--------------- 513 0,0 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCu-------------- 17 0,0 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCA-------------- 255 0,1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAu------------- 11 0,1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAuu------------ 10 0,1 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAA------------- 19 0,2 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAAa------------ 15 0,2 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAAu------------ 21 0,2 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAAuu----------- 2 0,2 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAAG------------ 11 0,3 ----------------------------------------------------UAAGGCACGCGGUGAAUGCCAAGA----------- 2 0,4 -----------------------------------------------------AAGGCACGCGGUGAAUGC---------------- 5 1,-1 -----------------------------------------------------AAGGCACGCGGUGAAUGCC--------------- 11 1,0 -----------------------------------------------------AAGGCACGCGGUGAAUGCCA-------------- 13 1,1 -----------------------------------------------------AAGGCACGCGGUGAAUGCCAA------------- 2 1,2 ------------------------------------------------------AGGCACGCGGUGAAUGCCA-------------- 2 2,1 >hsa-mir-1245 3pM:45-65 Tumor auuuauguauaggccuuuagaucaucugauguugaauacucuuuAAGUGAUCUAAAGGCCUACAUauaaa --------------------------------------------AAGUGAUCUAAAGGCCUACAUAU--- 2 0,2 >hsa-mir-1246 5pM:11-29 Tumor uguauccuugAAUGGAUUUUUGGAGCAGGaguggacaccugacccaaaggaaaucaauccauaggcuagcaau ----------AAUGGAUUUUUGGAGCAG--------------------------------------------- 5 0,-1 ----------AAUGGAUUUUUGGAGCAGG-------------------------------------------- 3698 0,0 ----------AAUGGAUUUUUGGAGCAGGg------------------------------------------- 452 0,0 ----------AAUGGAUUUUUGGAGCAGGA------------------------------------------- 4 0,1 -----------AUGGAUUUUUGGAGCAGG-------------------------------------------- 1558 1,0 -----------AUGGAUUUUUGGAGCAGGg------------------------------------------- 241 1,0 -----------AUGGAUUUUUGGAGCAGGA------------------------------------------- 2 1,1 ------------UGGAUUUUUGGAGCAGGA------------------------------------------- 7 2,1 ------------UGGAUUUUUGGAGCAGGAG------------------------------------------ 3 2,2 >hsa-mir-1247 5pM:40-61 Tumor ccgcuugccucgcccagcgcagccccggccgcugggcgcACCCGUCCCGUUCGUCCCCGGAcguugcucucuaccccgggaacgucgagacuggagcgcccgaacugagccaccuucgcggaccccgagagcggcg ---------------------------------------ACCCGUCCCGUUCGUCCCCG----------------------------------------------------------------------------- 3 0,-2 ---------------------------------------ACCCGUCCCGUUCGUCCCCGG---------------------------------------------------------------------------- 4 0,-1 ---------------------------------------ACCCGUCCCGUUCGUCCCCGGc--------------------------------------------------------------------------- 2 0,-1 ---------------------------------------ACCCGUCCCGUUCGUCCCCGGA--------------------------------------------------------------------------- 209 0,0 ---------------------------------------ACCCGUCCCGUUCGUCCCCGGAa-------------------------------------------------------------------------- 16 0,0 ---------------------------------------ACCCGUCCCGUUCGUCCCCGGAu-------------------------------------------------------------------------- 37 0,0 ---------------------------------------ACCCGUCCCGUUCGUCCCCGGAuu------------------------------------------------------------------------- 4 0,0 >hsa-mir-1248 5pM:4-30 Tumor uuuACCUUCUUGUAUAAGCACUGUGCUAAAauugcagacacuaggaccaugucuugguuuuugcaauaaugcuagcagaguacacacaagaagaaaaguaacagca ---ACCUUCUUGUAUAAGCACUGUG--------------------------------------------------------------------------------- 6 0,-5 ---ACCUUCUUGUAUAAGCACUGUGC-------------------------------------------------------------------------------- 8 0,-4 ---ACCUUCUUGUAUAAGCACUGUGCU------------------------------------------------------------------------------- 6 0,-3 -----------------------------------------------------------------------------------ACACAAGAAGAAAAGUAACAGCAc 2 ---------------------------------------------------------------------------------------AAGAAGAAAAGUAACAGCA 2 >hsa-mir-1249 3pM:41-62 Tumor gggaggagggaggagaugggccaaguucccucuggcuggaACGCCCUUCCCCCCCUUCUUCAccug ----------------------------------------ACGCCCUUCCCCCCCUUCU------- 13 0,-3 ----------------------------------------ACGCCCUUCCCCCCCUUCUU------ 16 0,-2 ----------------------------------------ACGCCCUUCCCCCCCUUCUUu----- 2 0,-2 ----------------------------------------ACGCCCUUCCCCCCCUUCUUC----- 35 0,-1 ----------------------------------------ACGCCCUUCCCCCCCUUCUUCc---- 2 0,-1 ----------------------------------------ACGCCCUUCCCCCCCUUCUUCu---- 11 0,-1 ----------------------------------------ACGCCCUUCCCCCCCUUCUUCA---- 113 0,0 ------------------------------------------GCCCUUCCCCCCCUUCUUa----- 2 2,-2 >hsa-mir-1250 5pM:24-44 Tumor cugucccgcuggccuggcaggugACGGUGCUGGAUGUGGCCUUUuugccuuuucuaaaggccacauuuuccagcccauucaaccuuccagagcccucugaaguggccacaggc -----------------------ACGGUGCUGGAUGUGGCCUUU--------------------------------------------------------------------- 5 0,0 -----------------------ACGGUGCUGGAUGUGGCCUUUU-------------------------------------------------------------------- 2 0,1 >hsa-mir-1251 5pM:5-25 Tumor guggACUCUAGCUGCCAAAGGCGCUucuccuucugaacagagcgcuuugcucagccaguguagacauggc ----ACUCUAGCUGCCAAAGGCGCU--------------------------------------------- 36 0,0 ----ACUCUAGCUGCCAAAGGCGCUU-------------------------------------------- 10 0,1 >hsa-mir-1252 5pM:5-26 Tumor agaaAGAAGGAAAUUGAAUUCAUUUAgaaaagagaauuccaaaugagcuuaauuuccuuuuuucu ----AGAAGGAAAUUGAAUUCA------------------------------------------- 2 0,-4 ----AGAAGGAAAUUGAAUUCAUUU---------------------------------------- 41 0,-1 ----AGAAGGAAAUUGAAUUCAUUUA--------------------------------------- 13 0,0 ------AAGGAAAUUGAAUUCAUUUAGA------------------------------------- 2 2,2 -----------------------------------------AAUGAGCUUAAUUUCCUUUUUU-- 6 >hsa-mir-1254 5pM:18-41 Tumor ggugggaggauugcuugAGCCUGGAAGCUGGAGCCUGCAGUgaacuaucauugugccacuguacuccagccuaggcaacaaaaugaaauccugucua -----------------AGCCUGGAAGCUGGAGCCUGCAG--------------------------------------------------------- 2 0,-1 -----------------AGCCUGGAAGCUGGAGCCUGCAGU-------------------------------------------------------- 12 0,0 -----------------------------------------------------UGCCACUGUACUCCAGCCU------------------------- 2 >hsa-mir-1254-2 5pM:4-27 Tumor cugAGCCUGGAAGCUGGAGCCUGCAGUgagcuaugaucaugucccuguacucuagccugggca ---AGCCUGGAAGCUGGAGCCUGCAG------------------------------------- 2 0,-1 ---AGCCUGGAAGCUGGAGCCUGCAGU------------------------------------ 12 0,0 >hsa-mir-1255a 5pM:28-50 Tumor auuggaaauccuuugaguugcuucucaAGGAUGAGCAAAGAAAGUAGAUUuuuuagauucuaaagaaacuaucuucuuugcucauccuugagaagcaacuccuuauccauuaa ---------------------------AGGAUGAGCAAAGAAAGUAGA----------------------------------------------------------------- 2 0,-2 ---------------------------AGGAUGAGCAAAGAAAGUAGAU---------------------------------------------------------------- 16 0,-1 ---------------------------AGGAUGAGCAAAGAAAGUAGAUU--------------------------------------------------------------- 18 0,0 >hsa-mir-1256 5pM:35-56 Tumor agucagccuguugaagcuuugaagcuuugaugccAGGCAUUGACUUCUCACUAGCUgugaaaguccuagcuaaagagaagucaaugcaugacaucuuguuucaauagauggcuguuuca ----------------------------------AGGCAUUGACUUCUCACUAGCU--------------------------------------------------------------- 5 0,0 ---------------------------------------------------------------------CUAAAGAGAAGUCAAUGCAUGA---------------------------- 5 >hsa-mir-125a 5p:15-38;3p:53-74 Tumor ugccagucucuaggUCCCUGAGACCCUUUAACCUGUGAggacauccagggucACAGGUGAGGUUCUUGGGAGCCuggcgucuggcc --------------UCCCUGAGACCCUUUAACC----------------------------------------------------- 128 0,-5 --------------UCCCUGAGACCCUUUAACCa---------------------------------------------------- 6 0,-5 --------------UCCCUGAGACCCUUUAACCU---------------------------------------------------- 614 0,-4 --------------UCCCUGAGACCCUUUAACCUa--------------------------------------------------- 4 0,-4 --------------UCCCUGAGACCCUUUAACCUau-------------------------------------------------- 61 0,-4 --------------UCCCUGAGACCCUUUAACCUu--------------------------------------------------- 7 0,-4 --------------UCCCUGAGACCCUUUAACCUuu-------------------------------------------------- 58 0,-4 --------------UCCCUGAGACCCUUUAACCUG--------------------------------------------------- 2632 0,-3 --------------UCCCUGAGACCCUUUAACCUGa-------------------------------------------------- 623 0,-3 --------------UCCCUGAGACCCUUUAACCUGaa------------------------------------------------- 2 0,-3 --------------UCCCUGAGACCCUUUAACCUGc-------------------------------------------------- 101 0,-3 --------------UCCCUGAGACCCUUUAACCUGg-------------------------------------------------- 18 0,-3 --------------UCCCUGAGACCCUUUAACCUGU-------------------------------------------------- 47725 0,-2 --------------UCCCUGAGACCCUUUAACCUGUa------------------------------------------------- 436 0,-2 --------------UCCCUGAGACCCUUUAACCUGUaa------------------------------------------------ 41 0,-2 --------------UCCCUGAGACCCUUUAACCUGUc------------------------------------------------- 7 0,-2 --------------UCCCUGAGACCCUUUAACCUGUu------------------------------------------------- 339 0,-2 --------------UCCCUGAGACCCUUUAACCUGUuu------------------------------------------------ 3 0,-2 --------------UCCCUGAGACCCUUUAACCUGUG------------------------------------------------- 26824 0,-1 --------------UCCCUGAGACCCUUUAACCUGUGc------------------------------------------------ 122 0,-1 --------------UCCCUGAGACCCUUUAACCUGUGg------------------------------------------------ 18 0,-1 --------------UCCCUGAGACCCUUUAACCUGUGu------------------------------------------------ 3796 0,-1 --------------UCCCUGAGACCCUUUAACCUGUGuu----------------------------------------------- 13 0,-1 --------------UCCCUGAGACCCUUUAACCUGUGA------------------------------------------------ 14489 0,0 --------------UCCCUGAGACCCUUUAACCUGUGAa----------------------------------------------- 132 0,0 --------------UCCCUGAGACCCUUUAACCUGUGAc----------------------------------------------- 2 0,0 --------------UCCCUGAGACCCUUUAACCUGUGAu----------------------------------------------- 65 0,0 ---------------CCCUGAGACCCUUUAACCUuu-------------------------------------------------- 4 1,-4 ---------------CCCUGAGACCCUUUAACCUG--------------------------------------------------- 2 1,-3 ---------------CCCUGAGACCCUUUAACCUGU-------------------------------------------------- 176 1,-2 ---------------CCCUGAGACCCUUUAACCUGUu------------------------------------------------- 2 1,-2 ---------------CCCUGAGACCCUUUAACCUGUG------------------------------------------------- 100 1,-1 ---------------CCCUGAGACCCUUUAACCUGUGA------------------------------------------------ 64 1,0 ----------------CCUGAGACCCUUUAACCUG--------------------------------------------------- 9 2,-3 ----------------CCUGAGACCCUUUAACCUGa-------------------------------------------------- 4 2,-3 ----------------CCUGAGACCCUUUAACCUGU-------------------------------------------------- 419 2,-2 ----------------CCUGAGACCCUUUAACCUGUG------------------------------------------------- 160 2,-1 ----------------CCUGAGACCCUUUAACCUGUGu------------------------------------------------ 23 2,-1 ----------------CCUGAGACCCUUUAACCUGUGA------------------------------------------------ 86 2,0 ----------------------------------------------------ACAGGUGAGGUUCUUGGGA--------------- 4 0,-3 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAG-------------- 80 0,-2 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAGa------------- 25 0,-2 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAGu------------- 10 0,-2 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAGC------------- 490 0,-1 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAGCu------------ 2 0,-1 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAGCC------------ 119 0,0 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAGCCa----------- 4 0,0 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAGCCau---------- 2 0,0 ----------------------------------------------------ACAGGUGAGGUUCUUGGGAGCCU----------- 4 0,1 -----------------------------------------------------CAGGUGAGGUUCUUGGGAaa------------- 2 1,-3 -----------------------------------------------------CAGGUGAGGUUCUUGGGAG-------------- 8 1,-2 -----------------------------------------------------CAGGUGAGGUUCUUGGGAGC------------- 6 1,-1 ------------------------------------------------------AGGUGAGGUUCUUGGGAGC------------- 2 2,-1 >hsa-mir-125b-1 MA:15-36;mi:55-76 Tumor ugcgcuccucucagUCCCUGAGACCCUAACUUGUGAuguuuaccguuuaaauccACGGGUUAGGCUCUUGGGAGCUgcgagucgugcu --------------UCCCUGAGACCCUAACUU-------------------------------------------------------- 931 0,-4 --------------UCCCUGAGACCCUAACUUa------------------------------------------------------- 38 0,-4 --------------UCCCUGAGACCCUAACUUaa------------------------------------------------------ 11 0,-4 --------------UCCCUGAGACCCUAACUUau------------------------------------------------------ 16 0,-4 --------------UCCCUGAGACCCUAACUUuu------------------------------------------------------ 2 0,-4 --------------UCCCUGAGACCCUAACUUG------------------------------------------------------- 1863 0,-3 --------------UCCCUGAGACCCUAACUUGa------------------------------------------------------ 219 0,-3 --------------UCCCUGAGACCCUAACUUGaa----------------------------------------------------- 8 0,-3 --------------UCCCUGAGACCCUAACUUGc------------------------------------------------------ 12 0,-3 --------------UCCCUGAGACCCUAACUUGg------------------------------------------------------ 4 0,-3 --------------UCCCUGAGACCCUAACUUGU------------------------------------------------------ 14151 0,-2 --------------UCCCUGAGACCCUAACUUGUa----------------------------------------------------- 160 0,-2 --------------UCCCUGAGACCCUAACUUGUaa---------------------------------------------------- 511 0,-2 --------------UCCCUGAGACCCUAACUUGUau---------------------------------------------------- 11 0,-2 --------------UCCCUGAGACCCUAACUUGUc----------------------------------------------------- 2 0,-2 --------------UCCCUGAGACCCUAACUUGUu----------------------------------------------------- 49 0,-2 --------------UCCCUGAGACCCUAACUUGUuu---------------------------------------------------- 6 0,-2 --------------UCCCUGAGACCCUAACUUGUG----------------------------------------------------- 22417 0,-1 --------------UCCCUGAGACCCUAACUUGUGc---------------------------------------------------- 1637 0,-1 --------------UCCCUGAGACCCUAACUUGUGg---------------------------------------------------- 232 0,-1 --------------UCCCUGAGACCCUAACUUGUGu---------------------------------------------------- 4817 0,-1 --------------UCCCUGAGACCCUAACUUGUGuu--------------------------------------------------- 10 0,-1 --------------UCCCUGAGACCCUAACUUGUGA---------------------------------------------------- 182835 0,0 --------------UCCCUGAGACCCUAACUUGUGAa--------------------------------------------------- 17209 0,0 --------------UCCCUGAGACCCUAACUUGUGAaa-------------------------------------------------- 2403 0,0 --------------UCCCUGAGACCCUAACUUGUGAau-------------------------------------------------- 151 0,0 --------------UCCCUGAGACCCUAACUUGUGAc--------------------------------------------------- 184 0,0 --------------UCCCUGAGACCCUAACUUGUGAU--------------------------------------------------- 918 0,1 --------------UCCCUGAGACCCUAACUUGUGAUa-------------------------------------------------- 6 0,1 --------------UCCCUGAGACCCUAACUUGUGAUu-------------------------------------------------- 9 0,1 ---------------CCCUGAGACCCUAACUUGU------------------------------------------------------ 10 1,-2 ---------------CCCUGAGACCCUAACUUGUG----------------------------------------------------- 38 1,-1 ---------------CCCUGAGACCCUAACUUGUGu---------------------------------------------------- 11 1,-1 ---------------CCCUGAGACCCUAACUUGUGA---------------------------------------------------- 619 1,0 ---------------CCCUGAGACCCUAACUUGUGAa--------------------------------------------------- 63 1,0 ---------------CCCUGAGACCCUAACUUGUGAaa-------------------------------------------------- 10 1,0 ----------------CCUGAGACCCUAACUUGU------------------------------------------------------ 72 2,-2 ----------------CCUGAGACCCUAACUUGUu----------------------------------------------------- 2 2,-2 ----------------CCUGAGACCCUAACUUGUG----------------------------------------------------- 138 2,-1 ----------------CCUGAGACCCUAACUUGUGu---------------------------------------------------- 27 2,-1 ----------------CCUGAGACCCUAACUUGUGA---------------------------------------------------- 1602 2,0 ----------------CCUGAGACCCUAACUUGUGAa--------------------------------------------------- 96 2,0 ----------------CCUGAGACCCUAACUUGUGAaa-------------------------------------------------- 6 2,0 ----------------CCUGAGACCCUAACUUGUGAU--------------------------------------------------- 2 2,1 ------------------------------------------------------ACGGGUUAGGCUCUUGGGA--------------- 2 0,-3 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAG-------------- 76 0,-2 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGa------------- 6 0,-2 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGu------------- 145 0,-2 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGC------------- 100 0,-1 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGCau----------- 4 0,-1 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGCU------------ 525 0,0 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGCUa----------- 13 0,0 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGCUau---------- 4 0,0 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGCUu----------- 93 0,0 ------------------------------------------------------ACGGGUUAGGCUCUUGGGAGCUuu---------- 12 0,0 -------------------------------------------------------CGGGUUAGGCUCUUGGGAGCU------------ 2 1,0 >hsa-mir-125b-2 MA:17-38;mi:54-75 Tumor accagacuuuuccuagUCCCUGAGACCCUAACUUGUGAgguauuuuaguaacaUCACAAGUCAGGCUCUUGGGACcuaggcggagggga ----------------UCCCUGAGACCCUAACUU------------------------------------------------------- 931 0,-4 ----------------UCCCUGAGACCCUAACUUa------------------------------------------------------ 38 0,-4 ----------------UCCCUGAGACCCUAACUUaa----------------------------------------------------- 11 0,-4 ----------------UCCCUGAGACCCUAACUUau----------------------------------------------------- 16 0,-4 ----------------UCCCUGAGACCCUAACUUuu----------------------------------------------------- 2 0,-4 ----------------UCCCUGAGACCCUAACUUG------------------------------------------------------ 1863 0,-3 ----------------UCCCUGAGACCCUAACUUGa----------------------------------------------------- 219 0,-3 ----------------UCCCUGAGACCCUAACUUGaa---------------------------------------------------- 8 0,-3 ----------------UCCCUGAGACCCUAACUUGc----------------------------------------------------- 12 0,-3 ----------------UCCCUGAGACCCUAACUUGg----------------------------------------------------- 4 0,-3 ----------------UCCCUGAGACCCUAACUUGU----------------------------------------------------- 14151 0,-2 ----------------UCCCUGAGACCCUAACUUGUa---------------------------------------------------- 160 0,-2 ----------------UCCCUGAGACCCUAACUUGUaa--------------------------------------------------- 511 0,-2 ----------------UCCCUGAGACCCUAACUUGUau--------------------------------------------------- 11 0,-2 ----------------UCCCUGAGACCCUAACUUGUc---------------------------------------------------- 2 0,-2 ----------------UCCCUGAGACCCUAACUUGUu---------------------------------------------------- 49 0,-2 ----------------UCCCUGAGACCCUAACUUGUuu--------------------------------------------------- 6 0,-2 ----------------UCCCUGAGACCCUAACUUGUG---------------------------------------------------- 22417 0,-1 ----------------UCCCUGAGACCCUAACUUGUGc--------------------------------------------------- 1637 0,-1 ----------------UCCCUGAGACCCUAACUUGUGg--------------------------------------------------- 232 0,-1 ----------------UCCCUGAGACCCUAACUUGUGu--------------------------------------------------- 4817 0,-1 ----------------UCCCUGAGACCCUAACUUGUGuu-------------------------------------------------- 10 0,-1 ----------------UCCCUGAGACCCUAACUUGUGA--------------------------------------------------- 182835 0,0 ----------------UCCCUGAGACCCUAACUUGUGAa-------------------------------------------------- 17209 0,0 ----------------UCCCUGAGACCCUAACUUGUGAaa------------------------------------------------- 2403 0,0 ----------------UCCCUGAGACCCUAACUUGUGAau------------------------------------------------- 151 0,0 ----------------UCCCUGAGACCCUAACUUGUGAc-------------------------------------------------- 184 0,0 ----------------UCCCUGAGACCCUAACUUGUGAG-------------------------------------------------- 208 0,1 ----------------UCCCUGAGACCCUAACUUGUGAGa------------------------------------------------- 27 0,1 ----------------UCCCUGAGACCCUAACUUGUGAGu------------------------------------------------- 8 0,1 -----------------CCCUGAGACCCUAACUUGU----------------------------------------------------- 10 1,-2 -----------------CCCUGAGACCCUAACUUGUG---------------------------------------------------- 38 1,-1 -----------------CCCUGAGACCCUAACUUGUGu--------------------------------------------------- 11 1,-1 -----------------CCCUGAGACCCUAACUUGUGA--------------------------------------------------- 619 1,0 -----------------CCCUGAGACCCUAACUUGUGAa-------------------------------------------------- 63 1,0 -----------------CCCUGAGACCCUAACUUGUGAaa------------------------------------------------- 10 1,0 ------------------CCUGAGACCCUAACUUGU----------------------------------------------------- 72 2,-2 ------------------CCUGAGACCCUAACUUGUu---------------------------------------------------- 2 2,-2 ------------------CCUGAGACCCUAACUUGUG---------------------------------------------------- 138 2,-1 ------------------CCUGAGACCCUAACUUGUGu--------------------------------------------------- 27 2,-1 ------------------CCUGAGACCCUAACUUGUGA--------------------------------------------------- 1602 2,0 ------------------CCUGAGACCCUAACUUGUGAa-------------------------------------------------- 96 2,0 ------------------CCUGAGACCCUAACUUGUGAaa------------------------------------------------- 6 2,0 ----------------------------------------------------AUCACAAGUCAGGCUCUU------------------- 2 -1,-5 ----------------------------------------------------AUCACAAGUCAGGCUCUUGGa---------------- 2 -1,-3 ----------------------------------------------------AUCACAAGUCAGGCUCUUGGG---------------- 2 -1,-2 ----------------------------------------------------AUCACAAGUCAGGCUCUUGGGA--------------- 75 -1,-1 ----------------------------------------------------AUCACAAGUCAGGCUCUUGGGAa-------------- 9 -1,-1 ----------------------------------------------------AUCACAAGUCAGGCUCUUGGGAu-------------- 8 -1,-1 ----------------------------------------------------AUCACAAGUCAGGCUCUUGGGAC-------------- 52 -1,0 ----------------------------------------------------AUCACAAGUCAGGCUCUUGGGACa------------- 2 -1,0 -----------------------------------------------------UCACAAGUCAGGCUCUUGGGA--------------- 9 0,-1 -----------------------------------------------------UCACAAGUCAGGCUCUUGGGAa-------------- 4 0,-1 -----------------------------------------------------UCACAAGUCAGGCUCUUGGGAu-------------- 2 0,-1 -----------------------------------------------------UCACAAGUCAGGCUCUUGGGAC-------------- 27 0,0 -----------------------------------------------------UCACAAGUCAGGCUCUUGGGACu------------- 2 0,0 -------------------------------------------------------ACAAGUCAGGCUCUUGGG---------------- 4 2,-2 -------------------------------------------------------ACAAGUCAGGCUCUUGGGA--------------- 62 2,-1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGAa-------------- 35 2,-1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGAaa------------- 20 2,-1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGAau------------- 4 2,-1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGAu-------------- 10 2,-1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGAuu------------- 2 2,-1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGAC-------------- 387 2,0 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACa------------- 129 2,0 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACg------------- 2 2,0 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACu------------- 136 2,0 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACuu------------ 2 2,0 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACC------------- 509 2,1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCa------------ 3 2,1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCaa----------- 2 2,1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCau----------- 2 2,1 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCU------------ 1011 2,2 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCUu----------- 209 2,2 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCUuu---------- 243 2,2 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCUA----------- 40 2,3 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCUAu---------- 48 2,3 -------------------------------------------------------ACAAGUCAGGCUCUUGGGACCUAuu--------- 2 2,3 >hsa-mir-126 mi:15-35;MA:52-73 Tumor cgcuggcgacgggaCAUUAUUACUUUUGGUACGCGcugugacacuucaaacUCGUACCGUGAGUAAUAAUGCGccguccacggca -------------ACAUUAUUACUUUUGGUACG---------------------------------------------------- 2 -1,-2 -------------ACAUUAUUACUUUUGGUACGCG-------------------------------------------------- 26 -1,0 --------------CAUUAUUACUUUUGGUAC----------------------------------------------------- 586 0,-3 --------------CAUUAUUACUUUUGGUACa---------------------------------------------------- 12 0,-3 --------------CAUUAUUACUUUUGGUACu---------------------------------------------------- 4 0,-3 --------------CAUUAUUACUUUUGGUACG---------------------------------------------------- 2562 0,-2 --------------CAUUAUUACUUUUGGUACGa--------------------------------------------------- 89 0,-2 --------------CAUUAUUACUUUUGGUACGu--------------------------------------------------- 4 0,-2 --------------CAUUAUUACUUUUGGUACGC--------------------------------------------------- 3318 0,-1 --------------CAUUAUUACUUUUGGUACGCa-------------------------------------------------- 202 0,-1 --------------CAUUAUUACUUUUGGUACGCaa------------------------------------------------- 22 0,-1 --------------CAUUAUUACUUUUGGUACGCau------------------------------------------------- 2 0,-1 --------------CAUUAUUACUUUUGGUACGCc-------------------------------------------------- 11 0,-1 --------------CAUUAUUACUUUUGGUACGCu-------------------------------------------------- 183 0,-1 --------------CAUUAUUACUUUUGGUACGCuu------------------------------------------------- 4 0,-1 --------------CAUUAUUACUUUUGGUACGCG-------------------------------------------------- 33968 0,0 --------------CAUUAUUACUUUUGGUACGCGa------------------------------------------------- 6054 0,0 --------------CAUUAUUACUUUUGGUACGCGaa------------------------------------------------ 90 0,0 --------------CAUUAUUACUUUUGGUACGCGau------------------------------------------------ 4 0,0 --------------CAUUAUUACUUUUGGUACGCGg------------------------------------------------- 21 0,0 --------------CAUUAUUACUUUUGGUACGCGu------------------------------------------------- 2490 0,0 --------------CAUUAUUACUUUUGGUACGCGuu------------------------------------------------ 24 0,0 --------------CAUUAUUACUUUUGGUACGCGC------------------------------------------------- 232 0,1 --------------CAUUAUUACUUUUGGUACGCGCa------------------------------------------------ 2 0,1 --------------CAUUAUUACUUUUGGUACGCGCU------------------------------------------------ 72 0,2 ---------------AUUAUUACUUUUGGUACG---------------------------------------------------- 59 1,-2 ---------------AUUAUUACUUUUGGUACGC--------------------------------------------------- 86 1,-1 ---------------AUUAUUACUUUUGGUACGCa-------------------------------------------------- 2 1,-1 ---------------AUUAUUACUUUUGGUACGCu-------------------------------------------------- 2 1,-1 ---------------AUUAUUACUUUUGGUACGCG-------------------------------------------------- 1215 1,0 ---------------AUUAUUACUUUUGGUACGCGa------------------------------------------------- 175 1,0 ---------------AUUAUUACUUUUGGUACGCGu------------------------------------------------- 54 1,0 ---------------AUUAUUACUUUUGGUACGCGC------------------------------------------------- 16 1,1 ---------------AUUAUUACUUUUGGUACGCGCa------------------------------------------------ 2 1,1 ---------------AUUAUUACUUUUGGUACGCGCU------------------------------------------------ 191 1,2 ----------------UUAUUACUUUUGGUACGCG-------------------------------------------------- 2 2,0 ----------------UUAUUACUUUUGGUACGCGC------------------------------------------------- 2 2,1 --------------------------------------------------CUCGUACCGUGAGUAAUA----------------- 11 -1,-5 --------------------------------------------------CUCGUACCGUGAGUAAUAA---------------- 19 -1,-4 --------------------------------------------------CUCGUACCGUGAGUAAUAAa--------------- 8 -1,-4 --------------------------------------------------CUCGUACCGUGAGUAAUAAaa-------------- 2 -1,-4 --------------------------------------------------CUCGUACCGUGAGUAAUAAU--------------- 298 -1,-3 --------------------------------------------------CUCGUACCGUGAGUAAUAAUG-------------- 715 -1,-2 --------------------------------------------------CUCGUACCGUGAGUAAUAAUGa------------- 175 -1,-2 --------------------------------------------------CUCGUACCGUGAGUAAUAAUGu------------- 10 -1,-2 --------------------------------------------------CUCGUACCGUGAGUAAUAAUGC------------- 1220 -1,-1 --------------------------------------------------CUCGUACCGUGAGUAAUAAUGCa------------ 26 -1,-1 --------------------------------------------------CUCGUACCGUGAGUAAUAAUGCc------------ 6 -1,-1 --------------------------------------------------CUCGUACCGUGAGUAAUAAUGCu------------ 6 -1,-1 --------------------------------------------------CUCGUACCGUGAGUAAUAAUGCG------------ 2468 -1,0 --------------------------------------------------CUCGUACCGUGAGUAAUAAUGCGa----------- 47 -1,0 --------------------------------------------------CUCGUACCGUGAGUAAUAAUGCGu----------- 25 -1,0 ---------------------------------------------------UCGUACCGUGAGUAAUAA---------------- 277 0,-4 ---------------------------------------------------UCGUACCGUGAGUAAUAAa--------------- 67 0,-4 ---------------------------------------------------UCGUACCGUGAGUAAUAAaa-------------- 37 0,-4 ---------------------------------------------------UCGUACCGUGAGUAAUAAU--------------- 2162 0,-3 ---------------------------------------------------UCGUACCGUGAGUAAUAAUa-------------- 88 0,-3 ---------------------------------------------------UCGUACCGUGAGUAAUAAUaa------------- 40 0,-3 ---------------------------------------------------UCGUACCGUGAGUAAUAAUu-------------- 22 0,-3 ---------------------------------------------------UCGUACCGUGAGUAAUAAUG-------------- 6670 0,-2 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGa------------- 1982 0,-2 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGaa------------ 249 0,-2 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGg------------- 4 0,-2 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGu------------- 269 0,-2 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGuu------------ 2 0,-2 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGC------------- 9104 0,-1 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCa------------ 1252 0,-1 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCaa----------- 160 0,-1 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCau----------- 2 0,-1 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCc------------ 81 0,-1 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCu------------ 264 0,-1 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCuu----------- 2 0,-1 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCG------------ 89395 0,0 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCGa----------- 13452 0,0 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCGaa---------- 20 0,0 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCGau---------- 6 0,0 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCGg----------- 37 0,0 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCGu----------- 3242 0,0 ---------------------------------------------------UCGUACCGUGAGUAAUAAUGCGC----------- 69 0,1 ----------------------------------------------------CGUACCGUGAGUAAUAAU--------------- 472 1,-3 ----------------------------------------------------CGUACCGUGAGUAAUAAUa-------------- 21 1,-3 ----------------------------------------------------CGUACCGUGAGUAAUAAUaa------------- 35 1,-3 ----------------------------------------------------CGUACCGUGAGUAAUAAUG-------------- 1786 1,-2 ----------------------------------------------------CGUACCGUGAGUAAUAAUGa------------- 773 1,-2 ----------------------------------------------------CGUACCGUGAGUAAUAAUGaa------------ 187 1,-2 ----------------------------------------------------CGUACCGUGAGUAAUAAUGu------------- 55 1,-2 ----------------------------------------------------CGUACCGUGAGUAAUAAUGC------------- 2446 1,-1 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCa------------ 561 1,-1 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCaa----------- 240 1,-1 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCau----------- 10 1,-1 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCc------------ 25 1,-1 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCu------------ 135 1,-1 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCuu----------- 13 1,-1 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCG------------ 56312 1,0 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCGa----------- 14401 1,0 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCGaa---------- 130 1,0 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCGau---------- 17 1,0 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCGg----------- 37 1,0 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCGu----------- 13026 1,0 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCGuu---------- 87 1,0 ----------------------------------------------------CGUACCGUGAGUAAUAAUGCGC----------- 114 1,1 -----------------------------------------------------GUACCGUGAGUAAUAAUG-------------- 72 2,-2 -----------------------------------------------------GUACCGUGAGUAAUAAUGa------------- 14 2,-2 -----------------------------------------------------GUACCGUGAGUAAUAAUGaa------------ 2 2,-2 -----------------------------------------------------GUACCGUGAGUAAUAAUGC------------- 121 2,-1 -----------------------------------------------------GUACCGUGAGUAAUAAUGCa------------ 10 2,-1 -----------------------------------------------------GUACCGUGAGUAAUAAUGCaa----------- 2 2,-1 -----------------------------------------------------GUACCGUGAGUAAUAAUGCau----------- 2 2,-1 -----------------------------------------------------GUACCGUGAGUAAUAAUGCu------------ 4 2,-1 -----------------------------------------------------GUACCGUGAGUAAUAAUGCG------------ 3268 2,0 -----------------------------------------------------GUACCGUGAGUAAUAAUGCGa----------- 727 2,0 -----------------------------------------------------GUACCGUGAGUAAUAAUGCGaa---------- 4 2,0 -----------------------------------------------------GUACCGUGAGUAAUAAUGCGu----------- 593 2,0 -----------------------------------------------------GUACCGUGAGUAAUAAUGCGC----------- 2 2,1 >hsa-mir-1260 5pM:14-31 Tumor accuuuccagcucAUCCCACCUCUGCCACCAaaacacucaucgcggggucagagggagugccaaaaaagguaa -------------AUCCCACCUCUGCCACCA------------------------------------------ 2 0,0 >hsa-mir-1260b 5pM:10-28 Tumor ucuccguuuAUCCCACCACUGCCACCAUuauugcuacuguucagcaggugcugcugguggugauggugauagucuggugggggcggugg ---------AUCCCACCACUGCCACCA-------------------------------------------------------------- 687 0,-1 ---------AUCCCACCACUGCCACCAa------------------------------------------------------------- 4 0,-1 ---------AUCCCACCACUGCCACCAaa------------------------------------------------------------ 4 0,-1 ---------AUCCCACCACUGCCACCAau------------------------------------------------------------ 3 0,-1 ---------AUCCCACCACUGCCACCAU------------------------------------------------------------- 10 0,0 ---------AUCCCACCACUGCCACCAUU------------------------------------------------------------ 11 0,1 >hsa-mir-1262 5pM:14-35 Tumor aucuacaauggugAUGGGUGAAUUUGUAGAAGGAUgaaagucaaagaauccuucugggaacuaauuuuuggccuucaacaagaauugugauau -------------AUGGGUGAAUUUGUAGAAGGAU---------------------------------------------------------- 2 0,0 >hsa-mir-1267 5pM:12-32 Tumor cucccaaaucuCCUGUUGAAGUGUAAUCCCCAccuccagcauuggggauuacauuucaacaugagauuuggaugagga ------------------------------------------UGGGGAUUACAUUUCAACAUGA-------------- 2 >hsa-mir-1268 5pM:5-22 Tumor uagcCGGGCGUGGUGGUGGGGGccuguggucccagcuacuuuggaggcugag ----CGGGCGUGGUGGUGGGGG------------------------------ 240 0,0 >hsa-mir-1268b 5pM:4-23 Tumor accCGGGCGUGGUGGUGGGGGUGggugccuguaauuccagcuaguuggga ---CGGGCGUGGUGGUGGGGG----------------------------- 240 0,-2 >hsa-mir-1269 3pM:67-88 Tumor uggauugccuagaccagggaagccaguuggcauggcucaguccaagucugaccaccugaggaaugcCUGGACUGAGCCGUGCUACUGGcuucccuggucuccagc ------------------------AGUUGGCAUGGCUCAGUCCAAG----------------------------------------------------------- 4 ------------------------AGUUGGCAUGGCUCAGUCCAAGU---------------------------------------------------------- 22 ------------------------------------------------------------------CUGGACUGAGCCGUGCUA--------------------- 8 0,-4 ------------------------------------------------------------------CUGGACUGAGCCGUGCUAC-------------------- 2 0,-3 ------------------------------------------------------------------CUGGACUGAGCCGUGCUACU------------------- 65 0,-2 ------------------------------------------------------------------CUGGACUGAGCCGUGCUACUG------------------ 35 0,-1 ------------------------------------------------------------------CUGGACUGAGCCGUGCUACUGa----------------- 13 0,-1 ------------------------------------------------------------------CUGGACUGAGCCGUGCUACUGu----------------- 17 0,-1 ------------------------------------------------------------------CUGGACUGAGCCGUGCUACUGG----------------- 69 0,0 ------------------------------------------------------------------CUGGACUGAGCCGUGCUACUGGa---------------- 7 0,0 ------------------------------------------------------------------CUGGACUGAGCCGUGCUACUGGu---------------- 10 0,0 -------------------------------------------------------------------UGGACUGAGCCGUGCUACUG------------------ 2 1,-1 -------------------------------------------------------------------UGGACUGAGCCGUGCUACUGG----------------- 4 1,0 >hsa-mir-1269b 5pM:9-30 Tumor ugagguuuCUGGACUGAGCCAUGCUACUGGcuucucugguucuccagcuuacagauggcuuaucaugggaccucu --------CUGGACUGAGCCAUGCUA------------------------------------------------- 20 0,-4 --------CUGGACUGAGCCAUGCUACU----------------------------------------------- 19 0,-2 --------CUGGACUGAGCCAUGCUACUG---------------------------------------------- 7 0,-1 --------CUGGACUGAGCCAUGCUACUGa--------------------------------------------- 4 0,-1 --------CUGGACUGAGCCAUGCUACUGu--------------------------------------------- 4 0,-1 --------CUGGACUGAGCCAUGCUACUGG--------------------------------------------- 25 0,0 --------CUGGACUGAGCCAUGCUACUGGa-------------------------------------------- 4 0,0 --------CUGGACUGAGCCAUGCUACUGGu-------------------------------------------- 2 0,0 >hsa-mir-127 5p:23-44;3p:57-78 Tumor ugugaucacugucuccagccugCUGAAGCUCAGAGGGCUCUGAUucagaaagaucaUCGGAUCCGUCUGAGCUUGGCUggucggaagucucaucauc --------------------UGCUGAAGCUCAGAGGGCUCUGAUU---------------------------------------------------- 2 -2,1 ---------------------GCUGAAGCUCAGAGGGCUCUGAU----------------------------------------------------- 5 -1,0 ----------------------CUGAAGCUCAGAGGGCUCUG------------------------------------------------------- 8 0,-2 ----------------------CUGAAGCUCAGAGGGCUCUGA------------------------------------------------------ 282 0,-1 ----------------------CUGAAGCUCAGAGGGCUCUGAa----------------------------------------------------- 11 0,-1 ----------------------CUGAAGCUCAGAGGGCUCUGAaa---------------------------------------------------- 12 0,-1 ----------------------CUGAAGCUCAGAGGGCUCUGAau---------------------------------------------------- 2 0,-1 ----------------------CUGAAGCUCAGAGGGCUCUGAU----------------------------------------------------- 1076 0,0 ----------------------CUGAAGCUCAGAGGGCUCUGAUa---------------------------------------------------- 38 0,0 ----------------------CUGAAGCUCAGAGGGCUCUGAUaa--------------------------------------------------- 2 0,0 ----------------------CUGAAGCUCAGAGGGCUCUGAUau--------------------------------------------------- 4 0,0 ----------------------CUGAAGCUCAGAGGGCUCUGAUU---------------------------------------------------- 819 0,1 ----------------------CUGAAGCUCAGAGGGCUCUGAUUu--------------------------------------------------- 23 0,1 -----------------------UGAAGCUCAGAGGGCUCU-------------------------------------------------------- 2 1,-3 -----------------------UGAAGCUCAGAGGGCUCUGA------------------------------------------------------ 16 1,-1 -----------------------UGAAGCUCAGAGGGCUCUGAa----------------------------------------------------- 2 1,-1 -----------------------UGAAGCUCAGAGGGCUCUGAaa---------------------------------------------------- 2 1,-1 -----------------------UGAAGCUCAGAGGGCUCUGAU----------------------------------------------------- 177 1,0 -----------------------UGAAGCUCAGAGGGCUCUGAUa---------------------------------------------------- 4 1,0 -----------------------UGAAGCUCAGAGGGCUCUGAUU---------------------------------------------------- 254 1,1 -----------------------UGAAGCUCAGAGGGCUCUGAUUu--------------------------------------------------- 6 1,1 -----------------------UGAAGCUCAGAGGGCUCUGAUUuu-------------------------------------------------- 2 1,1 ------------------------GAAGCUCAGAGGGCUCUGA------------------------------------------------------ 4 2,-1 ------------------------GAAGCUCAGAGGGCUCUGAU----------------------------------------------------- 36 2,0 ------------------------GAAGCUCAGAGGGCUCUGAUU---------------------------------------------------- 231 2,1 ------------------------GAAGCUCAGAGGGCUCUGAUUa--------------------------------------------------- 2 2,1 ------------------------GAAGCUCAGAGGGCUCUGAUUu--------------------------------------------------- 4 2,1 ------------------------GAAGCUCAGAGGGCUCUGAUUC--------------------------------------------------- 71 2,2 -------------------------------------------------------AUCGGAUCCGUCUGAGCUUGG--------------------- 8 -1,-2 -------------------------------------------------------AUCGGAUCCGUCUGAGCUUGGa-------------------- 6 -1,-2 -------------------------------------------------------AUCGGAUCCGUCUGAGCUUGGu-------------------- 83 -1,-2 --------------------------------------------------------UCGGAUCCGUCUGAGCUU----------------------- 17 0,-4 --------------------------------------------------------UCGGAUCCGUCUGAGCUUG---------------------- 25 0,-3 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGa--------------------- 4 0,-3 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGu--------------------- 4 0,-3 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGG--------------------- 614 0,-2 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGa-------------------- 103 0,-2 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGaa------------------- 21 0,-2 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGau------------------- 4 0,-2 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGu-------------------- 50 0,-2 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGuu------------------- 11 0,-2 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGC-------------------- 1098 0,-1 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCa------------------- 391 0,-1 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCaa------------------ 79 0,-1 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCau------------------ 108 0,-1 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCc------------------- 4 0,-1 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCg------------------- 4 0,-1 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCU------------------- 4945 0,0 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCUa------------------ 174 0,0 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCUaa----------------- 23 0,0 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCUau----------------- 109 0,0 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCUu------------------ 620 0,0 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCUuu----------------- 226 0,0 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCUG------------------ 8 0,1 --------------------------------------------------------UCGGAUCCGUCUGAGCUUGGCUGu----------------- 8 0,1 ---------------------------------------------------------CGGAUCCGUCUGAGCUUGG--------------------- 4 1,-2 ---------------------------------------------------------CGGAUCCGUCUGAGCUUGGC-------------------- 19 1,-1 ---------------------------------------------------------CGGAUCCGUCUGAGCUUGGCa------------------- 7 1,-1 ---------------------------------------------------------CGGAUCCGUCUGAGCUUGGCau------------------ 2 1,-1 ---------------------------------------------------------CGGAUCCGUCUGAGCUUGGCU------------------- 133 1,0 ---------------------------------------------------------CGGAUCCGUCUGAGCUUGGCUu------------------ 12 1,0 ---------------------------------------------------------CGGAUCCGUCUGAGCUUGGCUuu----------------- 2 1,0 ----------------------------------------------------------GGAUCCGUCUGAGCUUGG--------------------- 2 2,-2 ----------------------------------------------------------GGAUCCGUCUGAGCUUGGCU------------------- 6 2,0 >hsa-mir-1270-1 5pM:13-35 Tumor cacagaguuauaCUGGAGAUAUGGAAGAGCUGUGUuggguauaaguaacaggcuuuucuuuaucuucuauguggcucuuugca -----------ACUGGAGAUAUGGAAGAGCUGU-------------------------------------------------- 7 -1,-2 -----------ACUGGAGAUAUGGAAGAGCUGUGU------------------------------------------------ 6 -1,0 ------------CUGGAGAUAUGGAAGAGCUG--------------------------------------------------- 2 0,-3 ------------CUGGAGAUAUGGAAGAGCUGU-------------------------------------------------- 9 0,-2 ------------CUGGAGAUAUGGAAGAGCUGUu------------------------------------------------- 2 0,-2 ------------CUGGAGAUAUGGAAGAGCUGUG------------------------------------------------- 4 0,-1 ------------CUGGAGAUAUGGAAGAGCUGUGa------------------------------------------------ 4 0,-1 ------------CUGGAGAUAUGGAAGAGCUGUGU------------------------------------------------ 135 0,0 ------------CUGGAGAUAUGGAAGAGCUGUGUU----------------------------------------------- 4 0,1 -------------UGGAGAUAUGGAAGAGCUGUGU------------------------------------------------ 2 1,0 >hsa-mir-1270-2 5pM:13-35 Tumor cacagaguuauaCUGGAGAUAUGGAAGAGCUGUGUuggguauaaguaacaggcuuuucuuuaucuucuauguggcucuuugca -----------ACUGGAGAUAUGGAAGAGCUGU-------------------------------------------------- 7 -1,-2 -----------ACUGGAGAUAUGGAAGAGCUGUGU------------------------------------------------ 6 -1,0 ------------CUGGAGAUAUGGAAGAGCUG--------------------------------------------------- 2 0,-3 ------------CUGGAGAUAUGGAAGAGCUGU-------------------------------------------------- 9 0,-2 ------------CUGGAGAUAUGGAAGAGCUGUu------------------------------------------------- 2 0,-2 ------------CUGGAGAUAUGGAAGAGCUGUG------------------------------------------------- 4 0,-1 ------------CUGGAGAUAUGGAAGAGCUGUGa------------------------------------------------ 4 0,-1 ------------CUGGAGAUAUGGAAGAGCUGUGU------------------------------------------------ 135 0,0 ------------CUGGAGAUAUGGAAGAGCUGUGUU----------------------------------------------- 4 0,1 -------------UGGAGAUAUGGAAGAGCUGUGU------------------------------------------------ 2 1,0 >hsa-mir-1271 5pM:15-36 Tumor cacccagaucagugCUUGGCACCUAGCAAGCACUCAguaaauauuuguugagugccugcuaugugccaggcauugugcugagggcu --------------CUUGGCACCUAGCAAGCAC----------------------------------------------------- 2 0,-3 --------------CUUGGCACCUAGCAAGCACU---------------------------------------------------- 108 0,-2 --------------CUUGGCACCUAGCAAGCACUC--------------------------------------------------- 92 0,-1 --------------CUUGGCACCUAGCAAGCACUCg-------------------------------------------------- 2 0,-1 --------------CUUGGCACCUAGCAAGCACUCu-------------------------------------------------- 8 0,-1 --------------CUUGGCACCUAGCAAGCACUCA-------------------------------------------------- 240 0,0 --------------CUUGGCACCUAGCAAGCACUCAa------------------------------------------------- 2 0,0 ---------------UUGGCACCUAGCAAGCACUCA-------------------------------------------------- 2 1,0 --------------------------------------------------AGUGCCUGCUAUGUGCCAGG---------------- 2 --------------------------------------------------AGUGCCUGCUAUGUGCCAGGCAa------------- 4 >hsa-mir-1273 3pM:76-100 Tumor ugaggcaggagaauugcuugaacccgggugguggagguugcagugagccaagauugcgccacugcacuccagccuGGGCGACAAAGCAAGACUCUUUCUUgga UGAGGCAGGAGAAUUGCUU------------------------------------------------------------------------------------ 2 -GAGGCAGGAGAAUUGCUUGAACC------------------------------------------------------------------------------- 4 ------AGGAGAAUUGCUUGAACC------------------------------------------------------------------------------- 2 ------AGGAGAAUUGCUUGAACCu------------------------------------------------------------------------------ 2 -------------------------------UGGAGGUUGCAGUGAGCC------------------------------------------------------ 2 --------------------------------GGAGGUUGCAGUGAGCCAAGA-------------------------------------------------- 3 ---------------------------------GAGGUUGCAGUGAGCCAAG--------------------------------------------------- 2 ------------------------------------GUUGCAGUGAGCCAAGAU------------------------------------------------- 2 >hsa-mir-1273c 5pM:10-31 Tumor ugcagccugGGCGACAAAACGAGACCCUGUCuuuuuuuuuuucugagacagagucucguucuguugcccaagcugga ------------------------------------------------CAGAGUCUCGUUCUGUUG----------- 6 ------------------------------------------------CAGAGUCUCGUUCUGUUGCC--------- 4 ------------------------------------------------CAGAGUCUCGUUCUGUUGCCaa------- 2 ------------------------------------------------CAGAGUCUCGUUCUGUUGCCCA------- 2 >hsa-mir-1273d 5pM:10-34 Tumor gaaucgcuuGAACCCAUGAGGUUGAGGCUGCAGUgagccaagaucgugccacugcacuucagccugggugacaagagcgaaacuuc --------------------------------------------------ACUGCACUUCAGCCUGGGc----------------- 2 >hsa-mir-1273e 5pM:14-35 Tumor ugaggcaggagaaUUGCUUGAACCCAGGAAGUGGAggcugcagugagccgagaucgagccacuguacuccagccugggugacacagcgagacuccagucuca -----------------------------------------------------------CACUGUACUCCAGCCUGGG------------------------ 2 -----------------------------------------------------------------ACUCCAGCCUGGGUGACA------------------- 9 --------------------------------------------------------------------------UGGGUGACACAGCGAGACUC-------- 2 >hsa-mir-1273f 5pM:25-43 Tumor aggugggaggauugcuugagccugGGAGAUGGAGGUUGCAGUGagcugagaucacgcaacugcacccccagccugggccauagagucaguccuugucuc ---UGGGAGGAUUGCUUGAGCCc---------------------------------------------------------------------------- 2 >hsa-mir-1273g 5pM:26-47 Tumor gaggugggaggauugcuugagucagGGUGGUUGAGGCUGCAGUAAGUugugaucauaccacugcacuccagccugagugacagagcaagaccuugucuca --------------------------------------------------------ACCACUGCACUCCAGCCUG------------------------- 5 -----------------------------------------------------------ACUGCACUCCAGCCUGAG----------------------- 9 -----------------------------------------------------------ACUGCACUCCAGCCUGAGc---------------------- 5 ----------------------------------------------------------------ACUCCAGCCUGAGUGACAGA---------------- 2 >hsa-mir-1276 5pM:12-31 Tumor ccccagcuaggUAAAGAGCCCUGUGGAGACAccuggauucagagaacaugucuccacugagcacuugggccuugauggcggcu -----------UAAAGAGCCCUGUGGAGACA---------------------------------------------------- 2 0,0 >hsa-mir-1277 3pM:47-68 Tumor accucccaaauauauauauauauguacguauguguauauaaauguaUACGUAGAUAUAUAUGUAUUUUugguggguuu ----------UAUAUAUAUAUAUGUACGU------------------------------------------------- 7 ----------UAUAUAUAUAUAUGUACGUA------------------------------------------------ 27 ----------UAUAUAUAUAUAUGUACGUAU----------------------------------------------- 536 ----------UAUAUAUAUAUAUGUACGUAUa---------------------------------------------- 2 ----------UAUAUAUAUAUAUGUACGUAUaa--------------------------------------------- 2 ----------UAUAUAUAUAUAUGUACGUAUG---------------------------------------------- 516 ----------UAUAUAUAUAUAUGUACGUAUGa--------------------------------------------- 185 ----------UAUAUAUAUAUAUGUACGUAUGU--------------------------------------------- 52 ----------UAUAUAUAUAUAUGUACGUAUGUGU------------------------------------------- 6 -----------AUAUAUAUAUAUGUACGUAU----------------------------------------------- 4 -----------AUAUAUAUAUAUGUACGUAUG---------------------------------------------- 5 ------------UAUAUAUAUAUGUACGUAU----------------------------------------------- 4 ------------UAUAUAUAUAUGUACGUAUG---------------------------------------------- 13 ---------------------------------------------AUACGUAGAUAUAUAUGUAUUU----------- 13 -1,-1 ----------------------------------------------UACGUAGAUAUAUAUGUAU------------- 7 0,-3 ----------------------------------------------UACGUAGAUAUAUAUGUAUU------------ 73 0,-2 ----------------------------------------------UACGUAGAUAUAUAUGUAUUa----------- 2 0,-2 ----------------------------------------------UACGUAGAUAUAUAUGUAUUU----------- 370 0,-1 ----------------------------------------------UACGUAGAUAUAUAUGUAUUUU---------- 526 0,0 ----------------------------------------------UACGUAGAUAUAUAUGUAUUUUa--------- 7 0,0 ----------------------------------------------UACGUAGAUAUAUAUGUAUUUUU--------- 2 0,1 -----------------------------------------------ACGUAGAUAUAUAUGUAUUU----------- 8 1,-1 -----------------------------------------------ACGUAGAUAUAUAUGUAUUUU---------- 22 1,0 >hsa-mir-1278 3pM:50-71 Tumor auuugcucauagaugauaugcauaguacucccagaacucauuaaguuggUAGUACUGUGCAUAUCAUCUAUgagcgaauag -------------------------------------------------UAGUACUGUGCAUAUCAUCUAU---------- 4 0,0 >hsa-mir-128-1 3pM:50-70 Tumor ugagcuguuggauucggggccguagcacugucugagagguuuacauuucUCACAGUGAACCGGUCUCUUUuucagcugcuuc ------------------------------------------------CUCACAGUGAACCGGUCUCUU------------- 2 -1,-1 -------------------------------------------------UCACAGUGAACCGGUCUC--------------- 2 0,-3 -------------------------------------------------UCACAGUGAACCGGUCUCa-------------- 2 0,-3 -------------------------------------------------UCACAGUGAACCGGUCUCU-------------- 518 0,-2 -------------------------------------------------UCACAGUGAACCGGUCUCUa------------- 3 0,-2 -------------------------------------------------UCACAGUGAACCGGUCUCUaa------------ 13 0,-2 -------------------------------------------------UCACAGUGAACCGGUCUCUau------------ 5 0,-2 -------------------------------------------------UCACAGUGAACCGGUCUCUU------------- 938 0,-1 -------------------------------------------------UCACAGUGAACCGGUCUCUUa------------ 118 0,-1 -------------------------------------------------UCACAGUGAACCGGUCUCUUaa----------- 54 0,-1 -------------------------------------------------UCACAGUGAACCGGUCUCUUau----------- 25 0,-1 -------------------------------------------------UCACAGUGAACCGGUCUCUUU------------ 5035 0,0 -------------------------------------------------UCACAGUGAACCGGUCUCUUUa----------- 345 0,0 -------------------------------------------------UCACAGUGAACCGGUCUCUUUaa---------- 122 0,0 -------------------------------------------------UCACAGUGAACCGGUCUCUUUau---------- 70 0,0 -------------------------------------------------UCACAGUGAACCGGUCUCUUUU----------- 1245 0,1 -------------------------------------------------UCACAGUGAACCGGUCUCUUUUa---------- 36 0,1 -------------------------------------------------UCACAGUGAACCGGUCUCUUUUaa--------- 2 0,1 -------------------------------------------------UCACAGUGAACCGGUCUCUUUUg---------- 2 0,1 -------------------------------------------------UCACAGUGAACCGGUCUCUUUUU---------- 133 0,2 -------------------------------------------------UCACAGUGAACCGGUCUCUUUUUu--------- 5 0,2 --------------------------------------------------CACAGUGAACCGGUCUCU-------------- 2 1,-2 --------------------------------------------------CACAGUGAACCGGUCUCUU------------- 8 1,-1 --------------------------------------------------CACAGUGAACCGGUCUCUUaa----------- 2 1,-1 --------------------------------------------------CACAGUGAACCGGUCUCUUU------------ 53 1,0 --------------------------------------------------CACAGUGAACCGGUCUCUUUU----------- 10 1,1 ---------------------------------------------------ACAGUGAACCGGUCUCUUU------------ 15 2,0 >hsa-mir-128-2 3pM:52-72 Tumor ugugcagugggaaggggggccgauacacuguacgagagugaguagcaggucUCACAGUGAACCGGUCUCUUUcccuacuguguc --------------------------------------------------CUCACAGUGAACCGGUCUCUU------------- 2 -1,-1 ---------------------------------------------------UCACAGUGAACCGGUCUC--------------- 2 0,-3 ---------------------------------------------------UCACAGUGAACCGGUCUCa-------------- 2 0,-3 ---------------------------------------------------UCACAGUGAACCGGUCUCU-------------- 518 0,-2 ---------------------------------------------------UCACAGUGAACCGGUCUCUa------------- 3 0,-2 ---------------------------------------------------UCACAGUGAACCGGUCUCUaa------------ 13 0,-2 ---------------------------------------------------UCACAGUGAACCGGUCUCUau------------ 5 0,-2 ---------------------------------------------------UCACAGUGAACCGGUCUCUU------------- 938 0,-1 ---------------------------------------------------UCACAGUGAACCGGUCUCUUa------------ 118 0,-1 ---------------------------------------------------UCACAGUGAACCGGUCUCUUaa----------- 54 0,-1 ---------------------------------------------------UCACAGUGAACCGGUCUCUUau----------- 25 0,-1 ---------------------------------------------------UCACAGUGAACCGGUCUCUUU------------ 5035 0,0 ---------------------------------------------------UCACAGUGAACCGGUCUCUUUa----------- 345 0,0 ---------------------------------------------------UCACAGUGAACCGGUCUCUUUaa---------- 122 0,0 ---------------------------------------------------UCACAGUGAACCGGUCUCUUUau---------- 70 0,0 ---------------------------------------------------UCACAGUGAACCGGUCUCUUUC----------- 21 0,1 ---------------------------------------------------UCACAGUGAACCGGUCUCUUUCa---------- 3 0,1 ----------------------------------------------------CACAGUGAACCGGUCUCU-------------- 2 1,-2 ----------------------------------------------------CACAGUGAACCGGUCUCUU------------- 8 1,-1 ----------------------------------------------------CACAGUGAACCGGUCUCUUaa----------- 2 1,-1 ----------------------------------------------------CACAGUGAACCGGUCUCUUU------------ 53 1,0 -----------------------------------------------------ACAGUGAACCGGUCUCUUU------------ 15 2,0 >hsa-mir-1283-1 5pM:14-35 Tumor cucaagcuaugagUCUACAAAGGAAAGCGCUUUCUguugucagaaagaagagaaagcgcuucccuuuugaggguuacgguuugagaa -------------UCUACAAAGGAAAGCGCUUU------------------------------------------------------ 4 0,-2 -------------UCUACAAAGGAAAGCGCUUUC----------------------------------------------------- 3 0,-1 -------------UCUACAAAGGAAAGCGCUUUCU---------------------------------------------------- 72 0,0 --------------CUACAAAGGAAAGCGCUUU------------------------------------------------------ 6 1,-2 --------------CUACAAAGGAAAGCGCUUUC----------------------------------------------------- 9 1,-1 --------------CUACAAAGGAAAGCGCUUUCU---------------------------------------------------- 111 1,0 --------------CUACAAAGGAAAGCGCUUUCUu--------------------------------------------------- 2 1,0 --------------CUACAAAGGAAAGCGCUUUCUG--------------------------------------------------- 49 1,1 --------------CUACAAAGGAAAGCGCUUUCUGa-------------------------------------------------- 11 1,1 --------------CUACAAAGGAAAGCGCUUUCUGU-------------------------------------------------- 55 1,2 >hsa-mir-1283-2 5pM:14-35 Tumor cucaagcugugagUCUACAAAGGAAAGCGCUUUCUguugucugaaagaaaagaaaucgcuucccuuuggaguguuacgguuugagaa -------------UCUACAAAGGAAAGCGCUUU------------------------------------------------------ 4 0,-2 -------------UCUACAAAGGAAAGCGCUUUC----------------------------------------------------- 3 0,-1 -------------UCUACAAAGGAAAGCGCUUUCU---------------------------------------------------- 72 0,0 --------------CUACAAAGGAAAGCGCUUU------------------------------------------------------ 6 1,-2 --------------CUACAAAGGAAAGCGCUUUC----------------------------------------------------- 9 1,-1 --------------CUACAAAGGAAAGCGCUUUCU---------------------------------------------------- 111 1,0 --------------CUACAAAGGAAAGCGCUUUCUu--------------------------------------------------- 2 1,0 --------------CUACAAAGGAAAGCGCUUUCUG--------------------------------------------------- 49 1,1 --------------CUACAAAGGAAAGCGCUUUCUGa-------------------------------------------------- 11 1,1 --------------CUACAAAGGAAAGCGCUUUCUGU-------------------------------------------------- 55 1,2 ---------------------------------------------------GAAAUCGCUUCCCUUUGGA----------------- 2 ---------------------------------------------------GAAAUCGCUUCCCUUUGGAGU--------------- 6 ---------------------------------------------------GAAAUCGCUUCCCUUUGGAGUG-------------- 12 ----------------------------------------------------AAAUCGCUUCCCUUUGGAGU--------------- 16 ----------------------------------------------------AAAUCGCUUCCCUUUGGAGUG-------------- 6 ----------------------------------------------------AAAUCGCUUCCCUUUGGAGUGa------------- 4 >hsa-mir-1284 5pM:30-51 Tumor auuuugauauauaagccaguuuaauguuuUCUAUACAGACCCUGGCUUUUCuuaaauuuuauauauuggaaagcccauguuuguauuggaaacugcugguuucuuucauacugaaaaucu ------------------------------CUAUACAGACCCUGGCUUU----------------------------------------------------------------------- 2 1,-2 ------------------------------CUAUACAGACCCUGGCUUUU---------------------------------------------------------------------- 2 1,-1 --------------------------------------------------------------------GAAAGCCCAUGUUUGUAUUGGA------------------------------ 4 >hsa-mir-1285-1 3pM:51-72 Tumor uguagagauaggaucucacuuuguugcccaggcuggucucaaacuccuggUCUGGGCAACAAAGUGAGACCUuaucucuacaag ------------AUCUCACUUUGUUGCCCAG----------------------------------------------------- 3 ------------AUCUCACUUUGUUGCCCAGGC--------------------------------------------------- 2 ------------AUCUCACUUUGUUGCCCAGGCU-------------------------------------------------- 4 ------------AUCUCACUUUGUUGCCCAGGCUau------------------------------------------------ 2 ------------AUCUCACUUUGUUGCCCAGGCUu------------------------------------------------- 2 --------------------------------------------------UCUGGGCAACAAAGUGAGA--------------- 15 0,-3 --------------------------------------------------UCUGGGCAACAAAGUGAGAC-------------- 28 0,-2 --------------------------------------------------UCUGGGCAACAAAGUGAGACa------------- 9 0,-2 --------------------------------------------------UCUGGGCAACAAAGUGAGACC------------- 17 0,-1 --------------------------------------------------UCUGGGCAACAAAGUGAGACCU------------ 17 0,0 --------------------------------------------------UCUGGGCAACAAAGUGAGACCUa----------- 2 0,0 --------------------------------------------------UCUGGGCAACAAAGUGAGACCUU----------- 2 0,1 >hsa-mir-1285-2 3pM:52-73 Tumor uuugggaggccgaggcuggugcaucacuugagcccagcaauuugagaccaaUCUGGGCAACAAAGUGAGACCUccgucucuacaaaga ---------------------------------------------------UCUGGGCAACAAAGUGAGA------------------ 15 0,-3 ---------------------------------------------------UCUGGGCAACAAAGUGAGAC----------------- 28 0,-2 ---------------------------------------------------UCUGGGCAACAAAGUGAGACa---------------- 9 0,-2 ---------------------------------------------------UCUGGGCAACAAAGUGAGACC---------------- 17 0,-1 ---------------------------------------------------UCUGGGCAACAAAGUGAGACCU--------------- 17 0,0 ---------------------------------------------------UCUGGGCAACAAAGUGAGACCUa-------------- 2 0,0 >hsa-mir-1286 3pM:47-67 Tumor uguccucuggggacucagcuugcucuggcugcuggauugaauuagcUGCAGGACCAAGAUGAGCCCUugguggagaca ----------------------------------------------UGCAGGACCAAGAUGAGCCCU----------- 2 0,0 >hsa-mir-1287 5pM:16-37 Tumor guugugcuguccaggUGCUGGAUCAGUGGUUCGAGUCugagccuuuaaaagccacucuagccacagaugcagugauuggagccaugacaa ---------------UGCUGGAUCAGUGGUUCGA-------------------------------------------------------- 3 0,-3 ---------------UGCUGGAUCAGUGGUUCGAG------------------------------------------------------- 55 0,-2 ---------------UGCUGGAUCAGUGGUUCGAGa------------------------------------------------------ 9 0,-2 ---------------UGCUGGAUCAGUGGUUCGAGaa----------------------------------------------------- 2 0,-2 ---------------UGCUGGAUCAGUGGUUCGAGU------------------------------------------------------ 231 0,-1 ---------------UGCUGGAUCAGUGGUUCGAGUa----------------------------------------------------- 2 0,-1 ---------------UGCUGGAUCAGUGGUUCGAGUuu---------------------------------------------------- 2 0,-1 ---------------UGCUGGAUCAGUGGUUCGAGUC----------------------------------------------------- 149 0,0 ---------------UGCUGGAUCAGUGGUUCGAGUCa---------------------------------------------------- 28 0,0 ---------------UGCUGGAUCAGUGGUUCGAGUCU---------------------------------------------------- 17 0,1 ------------------------------------------------------CUCUAGCCACAGAUGCAGUGA--------------- 4 ------------------------------------------------------CUCUAGCCACAGAUGCAGUGAU-------------- 57 -------------------------------------------------------UCUAGCCACAGAUGCAGUGAU-------------- 4 >hsa-mir-1289-1 3pM:86-108 Tumor uucucaauuuuuaguaggaauuaaaaacaaaacugguaaaugcagacucuugguuuccacccccagagaaucccuaaaccgggggUGGAGUCCAGGAAUCUGCAUUUUagaaaguacccagggugauucugauaauugggaaca -------------------------------------------------------------------------------------UGGAGUCCAGGAAUCUGCAUUU------------------------------------- 2 0,-1 >hsa-mir-1289-2 3pM:70-92 Tumor ccacgguccuaguuaaaaaggcacauuccuagacccugccucagaacuacugaacagagucacugggugUGGAGUCCAGGAAUCUGCAUUUUuaccccuaucgcccccgcc ---------------------------------------------------------------------UGGAGUCCAGGAAUCUGCAUUU-------------------- 2 0,-1 >hsa-mir-129-2 5p:15-35;3p:57-78 Tumor ugcccuucgcgaauCUUUUUGCGGUCUGGGCUUGCuguacauaacucaauagccggAAGCCCUUACCCCAAAAAGCAUuugcggagggcg --------------CUUUUUGCGGUCUGGGCUUG-------------------------------------------------------- 2 0,-1 --------------CUUUUUGCGGUCUGGGCUUGC------------------------------------------------------- 6 0,0 --------------------------------------------------------AAGCCCUUACCCCAAAAAG--------------- 2 0,-3 --------------------------------------------------------AAGCCCUUACCCCAAAAAGCA------------- 8 0,-1 --------------------------------------------------------AAGCCCUUACCCCAAAAAGCAU------------ 29 0,0 >hsa-mir-1290 3pM:53-71 Tumor gagcgucacguugacacucaaaaaguuucagauuuuggaacauuucggauuuUGGAUUUUUGGAUCAGGGAugcucaa -----------------------------------------------------GGAUUUUUGGAUCAGGGAg------ 2 1,0 >hsa-mir-1291 5pM:14-37 Tumor gguagaauuccagUGGCCCUGACUGAAGACCAGCAGUuguacuguggcuguugguuucaagcagaggccuaaaggacugucuuccug ----------------------------------------------------------------AGGCCUAAAGGACUGUCUUCCUGu 2 >hsa-mir-1292 5pM:3-27 Tumor ccUGGGAACGGGUUCCGGCAGACGCUGagguugcguugacgcucgcgccccggcucccguuccagg --UGGGAACGGGUUCCGGCAGA-------------------------------------------- 4 0,-5 --UGGGAACGGGUUCCGGCAGACG------------------------------------------ 8 0,-3 --UGGGAACGGGUUCCGGCAGACGCU---------------------------------------- 8 0,-1 >hsa-mir-1294 5pM:48-69 Tumor caccuaaugugugccaagaucuguucauuuaugaucucaccgaguccUGUGAGGUUGGCAUUGUUGUCUggcauugucugauauacaacagugccaaccucacaggacucagugaggugaaacugaggauuaggaaggugua -----------------------------------------------UGUGAGGUUGGCAUUGUUGU--------------------------------------------------------------------------- 2 0,-2 -----------------------------------------------UGUGAGGUUGGCAUUGUUGUC-------------------------------------------------------------------------- 2 0,-1 -----------------------------------------------UGUGAGGUUGGCAUUGUUGUCU------------------------------------------------------------------------- 2 0,0 ------------------------------------------------------------------------------------ACAACAGUGCCAACCUCACAGG------------------------------------ 2 >hsa-mir-1295 3pM:49-69 Tumor aggacauuuugcccagauccguggccuauucagaaauguggccugugaUUAGGCCGCAGAUCUGGGUGAaauguccucc ------------------------------------------------UUAGGCCGCAGAUCUGGGUGA---------- 15 0,0 ------------------------------------------------UUAGGCCGCAGAUCUGGGUGAA--------- 3 0,1 ------------------------------------------------UUAGGCCGCAGAUCUGGGUGAAA-------- 4 0,2 >hsa-mir-1296 5pM:16-37 Tumor accuaccuaacugggUUAGGGCCCUGGCUCCAUCUCCuuuaggaaaaccuucuguggggaguggggcuucgacccuaacccaggugggcugu ---------------UUAGGGCCCUGGCUCCAU----------------------------------------------------------- 9 0,-4 ---------------UUAGGGCCCUGGCUCCAUu---------------------------------------------------------- 13 0,-4 ---------------UUAGGGCCCUGGCUCCAUuu--------------------------------------------------------- 2 0,-4 ---------------UUAGGGCCCUGGCUCCAUC---------------------------------------------------------- 87 0,-3 ---------------UUAGGGCCCUGGCUCCAUCa--------------------------------------------------------- 2 0,-3 ---------------UUAGGGCCCUGGCUCCAUCU--------------------------------------------------------- 96 0,-2 ---------------UUAGGGCCCUGGCUCCAUCUa-------------------------------------------------------- 2 0,-2 ---------------UUAGGGCCCUGGCUCCAUCUaa------------------------------------------------------- 2 0,-2 ---------------UUAGGGCCCUGGCUCCAUCUuu------------------------------------------------------- 3 0,-2 ---------------UUAGGGCCCUGGCUCCAUCUC-------------------------------------------------------- 36 0,-1 ---------------UUAGGGCCCUGGCUCCAUCUCa------------------------------------------------------- 7 0,-1 ---------------UUAGGGCCCUGGCUCCAUCUCu------------------------------------------------------- 16 0,-1 ---------------UUAGGGCCCUGGCUCCAUCUCuu------------------------------------------------------ 2 0,-1 ---------------UUAGGGCCCUGGCUCCAUCUCC------------------------------------------------------- 107 0,0 ---------------UUAGGGCCCUGGCUCCAUCUCCau----------------------------------------------------- 2 0,0 ---------------UUAGGGCCCUGGCUCCAUCUCCUU----------------------------------------------------- 2 0,2 ---------------UUAGGGCCCUGGCUCCAUCUCCUUU---------------------------------------------------- 4 0,3 ----------------UAGGGCCCUGGCUCCAUC---------------------------------------------------------- 2 1,-3 ----------------UAGGGCCCUGGCUCCAUCU--------------------------------------------------------- 2 1,-2 ----------------UAGGGCCCUGGCUCCAUCUCC------------------------------------------------------- 2 1,0 -----------------------------------------------------------AGUGGGGCUUCGACCCUAAuu------------ 2 -----------------------------------------------------------AGUGGGGCUUCGACCCUAACu------------ 2 -----------------------------------------------------------AGUGGGGCUUCGACCCUAACC------------ 36 ------------------------------------------------------------GUGGGGCUUCGACCCUAAuu------------ 2 >hsa-mir-1299 3pM:62-83 Tumor ccucauggcaguguucuggaauccuacgugagggacaaucauucagacccacguagcagugUUCUGGAAUUCUGUGUGAGGGA -------------------------------------------------------------UUCUGGAAUUCUGUGUGAG--- 4 0,-3 -------------------------------------------------------------UUCUGGAAUUCUGUGUGAGa-- 3 0,-3 -------------------------------------------------------------UUCUGGAAUUCUGUGUGAGG-- 13 0,-2 -------------------------------------------------------------UUCUGGAAUUCUGUGUGAGGa- 11 0,-2 -------------------------------------------------------------UUCUGGAAUUCUGUGUGAGGaa 9 0,-2 -------------------------------------------------------------UUCUGGAAUUCUGUGUGAGGau 4 0,-2 -------------------------------------------------------------UUCUGGAAUUCUGUGUGAGGGA 65 0,0 -------------------------------------------------------------UUCUGGAAUUCUGUGUGAGGGAa 12 0,0 -------------------------------------------------------------UUCUGGAAUUCUGUGUGAGGGAu 10 0,0 >hsa-mir-1301 3pM:48-71 Tumor ggauuguggggggucgcucuaggcaccgcagcacugugcuggggaugUUGCAGCUGCCUGGGAGUGACUUCacacaguccuc -----------------------------------------------UUGCAGCUGCCUGGGAGUG---------------- 7 0,-5 -----------------------------------------------UUGCAGCUGCCUGGGAGUGu--------------- 11 0,-5 -----------------------------------------------UUGCAGCUGCCUGGGAGUGA--------------- 251 0,-4 -----------------------------------------------UUGCAGCUGCCUGGGAGUGAa-------------- 18 0,-4 -----------------------------------------------UUGCAGCUGCCUGGGAGUGAaa------------- 6 0,-4 -----------------------------------------------UUGCAGCUGCCUGGGAGUGAu-------------- 16 0,-4 -----------------------------------------------UUGCAGCUGCCUGGGAGUGAC-------------- 347 0,-3 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACa------------- 22 0,-3 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACaa------------ 2 0,-3 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACau------------ 2 0,-3 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACU------------- 322 0,-2 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACUU------------ 146 0,-1 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACUUa----------- 4 0,-1 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACUUu----------- 56 0,-1 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACUUuu---------- 4 0,-1 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACUUC----------- 102 0,0 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACUUCu---------- 36 0,0 -----------------------------------------------UUGCAGCUGCCUGGGAGUGACUUCA---------- 32 0,1 ------------------------------------------------UGCAGCUGCCUGGGAGUGA--------------- 19 1,-4 ------------------------------------------------UGCAGCUGCCUGGGAGUGAC-------------- 25 1,-3 ------------------------------------------------UGCAGCUGCCUGGGAGUGACa------------- 2 1,-3 ------------------------------------------------UGCAGCUGCCUGGGAGUGACU------------- 36 1,-2 ------------------------------------------------UGCAGCUGCCUGGGAGUGACUU------------ 17 1,-1 ------------------------------------------------UGCAGCUGCCUGGGAGUGACUUu----------- 8 1,-1 ------------------------------------------------UGCAGCUGCCUGGGAGUGACUUC----------- 8 1,0 ------------------------------------------------UGCAGCUGCCUGGGAGUGACUUCu---------- 8 1,0 ------------------------------------------------UGCAGCUGCCUGGGAGUGACUUCA---------- 14 1,1 >hsa-mir-1303 3pM:52-73 Tumor ggcugggcaacauagcgagaccucaacucuacaauuuuuuuuuuuuuaaauUUUAGAGACGGGGUCUUGCUCUguugccaggcuuu --CUGGGCAACAUAGCGAGACC---------------------------------------------------------------- 2 ---UGGGCAACAUAGCGAGACC---------------------------------------------------------------- 9 -------------AGCGAGACCUCAACUCUACA----------------------------------------------------- 4 -------------AGCGAGACCUCAACUCUACAAU--------------------------------------------------- 2 -------------AGCGAGACCUCAACUCUACAAUU-------------------------------------------------- 2 -------------------------------------------------AUUUUAGAGACGGGGUCUUGa---------------- 2 -2,-4 -------------------------------------------------AUUUUAGAGACGGGGUCUUGCU--------------- 4 -2,-2 --------------------------------------------------UUUUAGAGACGGGGUCUUG----------------- 7 -1,-4 --------------------------------------------------UUUUAGAGACGGGGUCUUGa---------------- 2 -1,-4 --------------------------------------------------UUUUAGAGACGGGGUCUUGC---------------- 2 -1,-3 --------------------------------------------------UUUUAGAGACGGGGUCUUGCU--------------- 31 -1,-2 --------------------------------------------------UUUUAGAGACGGGGUCUUGCUC-------------- 2 -1,-1 --------------------------------------------------UUUUAGAGACGGGGUCUUGCUCU------------- 20 -1,0 --------------------------------------------------UUUUAGAGACGGGGUCUUGCUCUu------------ 2 -1,0 ---------------------------------------------------UUUAGAGACGGGGUCUUG----------------- 2 0,-4 ---------------------------------------------------UUUAGAGACGGGGUCUUGCU--------------- 3 0,-2 ---------------------------------------------------UUUAGAGACGGGGUCUUGCUC-------------- 2 0,-1 ---------------------------------------------------UUUAGAGACGGGGUCUUGCUCU------------- 16 0,0 >hsa-mir-1306 3pM:55-72 Tumor gugagcagucuccaccaccuccccugcaaacguccaguggugcagagguaauggACGUUGGCUCUGGUGGUGauggacaguccga --------------CCACCUCCCCUGCAAACGU---------------------------------------------------- 4 --------------CCACCUCCCCUGCAAACGUC--------------------------------------------------- 35 --------------CCACCUCCCCUGCAAACGUCa-------------------------------------------------- 2 --------------CCACCUCCCCUGCAAACGUCC-------------------------------------------------- 42 --------------CCACCUCCCCUGCAAACGUCCA------------------------------------------------- 74 --------------CCACCUCCCCUGCAAACGUCCAa------------------------------------------------ 2 --------------CCACCUCCCCUGCAAACGUCCAu------------------------------------------------ 2 ---------------CACCUCCCCUGCAAACGUCCA------------------------------------------------- 3 ------------------------------------------------------ACGUUGGCUCUGGUGGUGAU----------- 5 0,2 ------------------------------------------------------ACGUUGGCUCUGGUGGUGAUuu--------- 2 0,2 ------------------------------------------------------ACGUUGGCUCUGGUGGUGAUG---------- 5 0,3 ------------------------------------------------------ACGUUGGCUCUGGUGGUGAUGu--------- 15 0,3 >hsa-mir-1307 3pM:80-101 Tumor caucaagacccagcugagucacugucacugccuaccaaucucgaccggaccucgaccggcucgucuguguugccaaucgACUCGGCGUGGCGUCGGUCGUGguagauaggcggucaugcauacgaauuuucagcucuuguucuggugac ---------------------------------------CUCGACCGGACCUCGACCGGCU---------------------------------------------------------------------------------------- 5 ----------------------------------------UCGACCGGACCUCGACCG------------------------------------------------------------------------------------------- 15 ----------------------------------------UCGACCGGACCUCGACCGa------------------------------------------------------------------------------------------ 8 ----------------------------------------UCGACCGGACCUCGACCGaa----------------------------------------------------------------------------------------- 2 ----------------------------------------UCGACCGGACCUCGACCGG------------------------------------------------------------------------------------------ 87 ----------------------------------------UCGACCGGACCUCGACCGGa----------------------------------------------------------------------------------------- 19 ----------------------------------------UCGACCGGACCUCGACCGGaa---------------------------------------------------------------------------------------- 2 ----------------------------------------UCGACCGGACCUCGACCGGC----------------------------------------------------------------------------------------- 424 ----------------------------------------UCGACCGGACCUCGACCGGCa---------------------------------------------------------------------------------------- 62 ----------------------------------------UCGACCGGACCUCGACCGGCau--------------------------------------------------------------------------------------- 2 ----------------------------------------UCGACCGGACCUCGACCGGCc---------------------------------------------------------------------------------------- 6 ----------------------------------------UCGACCGGACCUCGACCGGCg---------------------------------------------------------------------------------------- 5 ----------------------------------------UCGACCGGACCUCGACCGGCU---------------------------------------------------------------------------------------- 5525 ----------------------------------------UCGACCGGACCUCGACCGGCUa--------------------------------------------------------------------------------------- 29 ----------------------------------------UCGACCGGACCUCGACCGGCUaa-------------------------------------------------------------------------------------- 7 ----------------------------------------UCGACCGGACCUCGACCGGCUau-------------------------------------------------------------------------------------- 4 ----------------------------------------UCGACCGGACCUCGACCGGCUu--------------------------------------------------------------------------------------- 34 ----------------------------------------UCGACCGGACCUCGACCGGCUuu-------------------------------------------------------------------------------------- 15 ----------------------------------------UCGACCGGACCUCGACCGGCUC--------------------------------------------------------------------------------------- 1060 ----------------------------------------UCGACCGGACCUCGACCGGCUCa-------------------------------------------------------------------------------------- 107 ----------------------------------------UCGACCGGACCUCGACCGGCUCau------------------------------------------------------------------------------------- 2 ----------------------------------------UCGACCGGACCUCGACCGGCUCc-------------------------------------------------------------------------------------- 56 ----------------------------------------UCGACCGGACCUCGACCGGCUCu-------------------------------------------------------------------------------------- 316 ----------------------------------------UCGACCGGACCUCGACCGGCUCuu------------------------------------------------------------------------------------- 6 ----------------------------------------UCGACCGGACCUCGACCGGCUCG-------------------------------------------------------------------------------------- 1701 ----------------------------------------UCGACCGGACCUCGACCGGCUCGa------------------------------------------------------------------------------------- 108 ----------------------------------------UCGACCGGACCUCGACCGGCUCGaa------------------------------------------------------------------------------------ 2 ----------------------------------------UCGACCGGACCUCGACCGGCUCGU------------------------------------------------------------------------------------- 30 ----------------------------------------UCGACCGGACCUCGACCGGCUCGUu------------------------------------------------------------------------------------ 19 -----------------------------------------CGACCGGACCUCGACCGGC----------------------------------------------------------------------------------------- 2 -----------------------------------------CGACCGGACCUCGACCGGCU---------------------------------------------------------------------------------------- 61 -----------------------------------------CGACCGGACCUCGACCGGCUC--------------------------------------------------------------------------------------- 4 -----------------------------------------CGACCGGACCUCGACCGGCUCG-------------------------------------------------------------------------------------- 10 ------------------------------------------GACCGGACCUCGACCGGC----------------------------------------------------------------------------------------- 2 ------------------------------------------GACCGGACCUCGACCGGCU---------------------------------------------------------------------------------------- 12 ------------------------------------------GACCGGACCUCGACCGGCUC--------------------------------------------------------------------------------------- 4 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGU---------------------------------------------------- 33 0,-4 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUa--------------------------------------------------- 2 0,-4 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUu--------------------------------------------------- 2 0,-4 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUC--------------------------------------------------- 16 0,-3 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCG-------------------------------------------------- 122 0,-2 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGa------------------------------------------------- 2 0,-2 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGU------------------------------------------------- 247 0,-1 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUu------------------------------------------------ 26 0,-1 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUuu----------------------------------------------- 7 0,-1 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUG------------------------------------------------ 455 0,0 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUGa----------------------------------------------- 98 0,0 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUGaa---------------------------------------------- 4 0,0 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUGau---------------------------------------------- 2 0,0 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUGu----------------------------------------------- 412 0,0 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUGG----------------------------------------------- 929 0,1 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUGGa---------------------------------------------- 51 0,1 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUGGau--------------------------------------------- 6 0,1 -------------------------------------------------------------------------------ACUCGGCGUGGCGUCGGUCGUGGU---------------------------------------------- 163 0,2 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCG-------------------------------------------------- 3 1,-2 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGU------------------------------------------------- 25 1,-1 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUuu----------------------------------------------- 2 1,-1 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUG------------------------------------------------ 73 1,0 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUGa----------------------------------------------- 15 1,0 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUGaa---------------------------------------------- 3 1,0 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUGu----------------------------------------------- 43 1,0 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUGG----------------------------------------------- 341 1,1 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUGGa---------------------------------------------- 21 1,1 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUGGau--------------------------------------------- 3 1,1 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUGGU---------------------------------------------- 61 1,2 --------------------------------------------------------------------------------CUCGGCGUGGCGUCGGUCGUGGUuu-------------------------------------------- 2 1,2 ---------------------------------------------------------------------------------UCGGCGUGGCGUCGGUCGUGG----------------------------------------------- 4 2,1 >hsa-mir-130a mi:21-42;MA:55-76 Tumor ugcugcuggccagagcucuuUUCACAUUGUGCUACUGUCUGCaccugucacuagCAGUGCAAUGUUAAAAGGGCAUuggccguguagug -----------------------------------------------------GCAGUGCAAUGUUAAAAGGGCAU------------- 9 -1,0 ------------------------------------------------------CAGUGCAAUGUUAAAAGG----------------- 244 0,-4 ------------------------------------------------------CAGUGCAAUGUUAAAAGGa---------------- 17 0,-4 ------------------------------------------------------CAGUGCAAUGUUAAAAGGu---------------- 2 0,-4 ------------------------------------------------------CAGUGCAAUGUUAAAAGGG---------------- 633 0,-3 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGa--------------- 118 0,-3 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGaa-------------- 26 0,-3 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGu--------------- 17 0,-3 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGC--------------- 1336 0,-2 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCc-------------- 6 0,-2 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCu-------------- 3 0,-2 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCuu------------- 17 0,-2 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCA-------------- 4375 0,-1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAa------------- 1420 0,-1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAaa------------ 155 0,-1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAau------------ 170 0,-1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAc------------- 1823 0,-1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAg------------- 49 0,-1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAU------------- 46573 0,0 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUa------------ 1048 0,0 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUaa----------- 292 0,0 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUau----------- 208 0,0 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUc------------ 10 0,0 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUg------------ 19 0,0 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUU------------ 10250 0,1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUUa----------- 582 0,1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUUaa---------- 12 0,1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUUau---------- 11 0,1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUUc----------- 2 0,1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUUu----------- 438 0,1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUUuu---------- 3 0,1 ------------------------------------------------------CAGUGCAAUGUUAAAAGGGCAUUG----------- 21 0,2 -------------------------------------------------------AGUGCAAUGUUAAAAGGG---------------- 6 1,-3 -------------------------------------------------------AGUGCAAUGUUAAAAGGGC--------------- 23 1,-2 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCA-------------- 128 1,-1 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAa------------- 30 1,-1 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAaa------------ 2 1,-1 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAc------------- 65 1,-1 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAU------------- 1870 1,0 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAUa------------ 16 1,0 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAUaa----------- 4 1,0 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAUau----------- 2 1,0 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAUU------------ 434 1,1 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAUUa----------- 5 1,1 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAUUu----------- 10 1,1 -------------------------------------------------------AGUGCAAUGUUAAAAGGGCAUUG----------- 2 1,2 --------------------------------------------------------GUGCAAUGUUAAAAGGGCAU------------- 23 2,0 --------------------------------------------------------GUGCAAUGUUAAAAGGGCAUU------------ 4 2,1 >hsa-mir-130b mi:13-33;MA:51-72 Tumor ggccugcccgacACUCUUUCCCUGUUGCACUACuauaggccgcugggaagCAGUGCAAUGAUGAAAGGGCAUcggucagguc ------------ACUCUUUCCCUGUUGCACU--------------------------------------------------- 166 0,-2 ------------ACUCUUUCCCUGUUGCACUA-------------------------------------------------- 71 0,-1 ------------ACUCUUUCCCUGUUGCACUAa------------------------------------------------- 6 0,-1 ------------ACUCUUUCCCUGUUGCACUAg------------------------------------------------- 2 0,-1 ------------ACUCUUUCCCUGUUGCACUAC------------------------------------------------- 129 0,0 ------------ACUCUUUCCCUGUUGCACUACa------------------------------------------------ 4 0,0 ------------ACUCUUUCCCUGUUGCACUACU------------------------------------------------ 895 0,1 ------------ACUCUUUCCCUGUUGCACUACUA----------------------------------------------- 2 0,2 -------------CUCUUUCCCUGUUGCACUACU------------------------------------------------ 2 1,1 -------------------------------------------------GCAGUGCAAUGAUGAAAGGGCAa---------- 2 -1,-1 --------------------------------------------------CAGUGCAAUGAUGAAAGG-------------- 14 0,-4 --------------------------------------------------CAGUGCAAUGAUGAAAGGG------------- 85 0,-3 --------------------------------------------------CAGUGCAAUGAUGAAAGGGa------------ 13 0,-3 --------------------------------------------------CAGUGCAAUGAUGAAAGGGC------------ 255 0,-2 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCuu---------- 2 0,-2 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCA----------- 697 0,-1 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAa---------- 349 0,-1 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAaa--------- 34 0,-1 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAau--------- 20 0,-1 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAc---------- 6 0,-1 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAg---------- 7 0,-1 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAU---------- 8055 0,0 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAUa--------- 152 0,0 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAUaa-------- 51 0,0 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAUau-------- 31 0,0 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAUg--------- 2 0,0 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAUu--------- 869 0,0 --------------------------------------------------CAGUGCAAUGAUGAAAGGGCAUuu-------- 139 0,0 ---------------------------------------------------AGUGCAAUGAUGAAAGGG------------- 2 1,-3 ---------------------------------------------------AGUGCAAUGAUGAAAGGGC------------ 4 1,-2 ---------------------------------------------------AGUGCAAUGAUGAAAGGGCA----------- 21 1,-1 ---------------------------------------------------AGUGCAAUGAUGAAAGGGCAa---------- 6 1,-1 ---------------------------------------------------AGUGCAAUGAUGAAAGGGCAU---------- 457 1,0 ---------------------------------------------------AGUGCAAUGAUGAAAGGGCAUa--------- 2 1,0 ---------------------------------------------------AGUGCAAUGAUGAAAGGGCAUu--------- 27 1,0 ---------------------------------------------------AGUGCAAUGAUGAAAGGGCAUuu-------- 4 1,0 ----------------------------------------------------GUGCAAUGAUGAAAGGGCAU---------- 6 2,0 >hsa-mir-132 mi:23-44;MA:59-80 Tumor ccgcccccgcgucuccagggcaACCGUGGCUUUCGAUUGUUACUgugggaacuggaggUAACAGUCUACAGCCAUGGUCGccccgcagcacgcccacgcgc ---------------------AACCGUGGCUUUCGAUUGUU------------------------------------------------------------ 32 -1,-3 ---------------------AACCGUGGCUUUCGAUUGUUA----------------------------------------------------------- 46 -1,-2 ---------------------AACCGUGGCUUUCGAUUGUUAa---------------------------------------------------------- 4 -1,-2 ---------------------AACCGUGGCUUUCGAUUGUUAC---------------------------------------------------------- 5 -1,-1 ----------------------ACCGUGGCUUUCGAUUGUU------------------------------------------------------------ 29 0,-3 ----------------------ACCGUGGCUUUCGAUUGUUA----------------------------------------------------------- 20 0,-2 ----------------------ACCGUGGCUUUCGAUUGUUAuu--------------------------------------------------------- 2 0,-2 ----------------------ACCGUGGCUUUCGAUUGUUAC---------------------------------------------------------- 78 0,-1 ----------------------ACCGUGGCUUUCGAUUGUUACU--------------------------------------------------------- 408 0,0 ----------------------------------------------------------UAACAGUCUACAGCCAUGG------------------------ 10 0,-3 ----------------------------------------------------------UAACAGUCUACAGCCAUGGU----------------------- 76 0,-2 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUa---------------------- 6 0,-2 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUaa--------------------- 10 0,-2 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUu---------------------- 5 0,-2 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUC---------------------- 127 0,-1 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUCa--------------------- 33 0,-1 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUCu--------------------- 28 0,-1 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUCG--------------------- 1643 0,0 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUCGa-------------------- 81 0,0 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUCGu-------------------- 314 0,0 ----------------------------------------------------------UAACAGUCUACAGCCAUGGUCGuu------------------- 8 0,0 -----------------------------------------------------------AACAGUCUACAGCCAUGGUC---------------------- 2 1,-1 -----------------------------------------------------------AACAGUCUACAGCCAUGGUCG--------------------- 82 1,0 -----------------------------------------------------------AACAGUCUACAGCCAUGGUCGu-------------------- 14 1,0 ------------------------------------------------------------ACAGUCUACAGCCAUGGUCG--------------------- 2 2,0 ------------------------------------------------------------ACAGUCUACAGCCAUGGUCGu-------------------- 7 2,0 >hsa-mir-1323 5pM:11-32 Tumor acugagguccUCAAAACUGAGGGGCAUUUUCUgugguuugaaaggaaagugcacccaguuuuggggaugucaa ----------UCAAAACUGAGGGGCAUUUUCU----------------------------------------- 11 0,0 >hsa-mir-133a-1 3pM:53-74 Tumor acaaugcuuugcuagagcugguaaaauggaaccaaaucgccucuucaauggaUUUGGUCCCCUUCAACCAGCUGuagcuaugcauuga ---------------AGCUGGUAAAAUGGAACCAAAU--------------------------------------------------- 4 ----------------------------------------------------UUUGGUCCCCUUCAACCAGCU--------------- 2 0,-1 ----------------------------------------------------UUUGGUCCCCUUCAACCAGCUG-------------- 6 0,0 ----------------------------------------------------UUUGGUCCCCUUCAACCAGCUGU------------- 40 0,1 -----------------------------------------------------UUGGUCCCCUUCAACCAGCUGU------------- 80 1,1 -----------------------------------------------------UUGGUCCCCUUCAACCAGCUGUu------------ 6 1,1 -----------------------------------------------------UUGGUCCCCUUCAACCAGCUGUA------------ 2 1,2 ------------------------------------------------------UGGUCCCCUUCAACCAGCUGU------------- 4 2,1 >hsa-mir-133a-2 3pM:59-80 Tumor gggagccaaaugcuuugcuagagcugguaaaauggaaccaaaucgacuguccaauggaUUUGGUCCCCUUCAACCAGCUGuagcugugcauugauggcgccg ---------------------AGCUGGUAAAAUGGAACCAAAU----------------------------------------------------------- 4 ----------------------------------------------------------UUUGGUCCCCUUCAACCAGCU----------------------- 2 0,-1 ----------------------------------------------------------UUUGGUCCCCUUCAACCAGCUG---------------------- 6 0,0 ----------------------------------------------------------UUUGGUCCCCUUCAACCAGCUGU--------------------- 40 0,1 -----------------------------------------------------------UUGGUCCCCUUCAACCAGCUGU--------------------- 80 1,1 -----------------------------------------------------------UUGGUCCCCUUCAACCAGCUGUu-------------------- 6 1,1 -----------------------------------------------------------UUGGUCCCCUUCAACCAGCUGUA-------------------- 2 1,2 ------------------------------------------------------------UGGUCCCCUUCAACCAGCUGU--------------------- 4 2,1 >hsa-mir-133b 3pM:66-87 Tumor ccucagaagaaagaugcccccugcucuggcuggucaaacggaaccaaguccgucuuccugagaggUUUGGUCCCCUUCAACCAGCUAcagcagggcuggcaaugcccaguccuuggaga -----------------------------------------------------------------UUUGGUCCCCUUCAACCAGCU--------------------------------- 2 0,-1 >hsa-mir-134 5pM:8-29 Tumor cagggugUGUGACUGGUUGACCAGAGGGGcaugcacuguguucacccugugggccaccuagucaccaacccuc -------UGUGACUGGUUGACCAGAaa---------------------------------------------- 4 0,-4 -------UGUGACUGGUUGACCAGAG----------------------------------------------- 10 0,-3 -------UGUGACUGGUUGACCAGAGa---------------------------------------------- 11 0,-3 -------UGUGACUGGUUGACCAGAGaa--------------------------------------------- 2 0,-3 -------UGUGACUGGUUGACCAGAGu---------------------------------------------- 2 0,-3 -------UGUGACUGGUUGACCAGAGG---------------------------------------------- 141 0,-2 -------UGUGACUGGUUGACCAGAGGa--------------------------------------------- 26 0,-2 -------UGUGACUGGUUGACCAGAGGaa-------------------------------------------- 16 0,-2 -------UGUGACUGGUUGACCAGAGGG--------------------------------------------- 168 0,-1 -------UGUGACUGGUUGACCAGAGGGa-------------------------------------------- 137 0,-1 -------UGUGACUGGUUGACCAGAGGGaa------------------------------------------- 49 0,-1 -------UGUGACUGGUUGACCAGAGGGau------------------------------------------- 14 0,-1 -------UGUGACUGGUUGACCAGAGGGu-------------------------------------------- 16 0,-1 -------UGUGACUGGUUGACCAGAGGGG-------------------------------------------- 465 0,0 -------UGUGACUGGUUGACCAGAGGGGa------------------------------------------- 71 0,0 -------UGUGACUGGUUGACCAGAGGGGaa------------------------------------------ 10 0,0 -------UGUGACUGGUUGACCAGAGGGGau------------------------------------------ 18 0,0 -------UGUGACUGGUUGACCAGAGGGGu------------------------------------------- 29 0,0 -------UGUGACUGGUUGACCAGAGGGGuu------------------------------------------ 2 0,0 --------GUGACUGGUUGACCAGAGGG--------------------------------------------- 3 1,-1 --------GUGACUGGUUGACCAGAGGGa-------------------------------------------- 2 1,-1 --------GUGACUGGUUGACCAGAGGGG-------------------------------------------- 10 1,0 ----------------------------------------------CUGUGGGCCACCUAGUCACC------- 2 >hsa-mir-1343 3pM:52-73 Tumor gcuggcgucggugcuggggagcggcccccgggugggccucugcucuggcccCUCCUGGGGCCCGCACUCUCGCucugggcccgc ---------------------------------------------------CUCCUGGGGCCCGCACUCUCG------------ 8 0,-1 ---------------------------------------------------CUCCUGGGGCCCGCACUCUCGCU---------- 2 0,1 >hsa-mir-135a-1 MA:17-39;mi:56-77 Tumor aggccucgcuguucucUAUGGCUUUUUAUUCCUAUGUGAuucuacugcucacucaUAUAGGGAUUGGAGCCGUGGCGcacggcggggaca ----------------UAUGGCUUUUUAUUCCUAUuu----------------------------------------------------- 2 0,-4 ----------------UAUGGCUUUUUAUUCCUAUGU----------------------------------------------------- 40 0,-2 ----------------UAUGGCUUUUUAUUCCUAUGUaa--------------------------------------------------- 3 0,-2 ----------------UAUGGCUUUUUAUUCCUAUGUu---------------------------------------------------- 2 0,-2 ----------------UAUGGCUUUUUAUUCCUAUGUG---------------------------------------------------- 74 0,-1 ----------------UAUGGCUUUUUAUUCCUAUGUGu--------------------------------------------------- 18 0,-1 ----------------UAUGGCUUUUUAUUCCUAUGUGA--------------------------------------------------- 449 0,0 ----------------UAUGGCUUUUUAUUCCUAUGUGAa-------------------------------------------------- 26 0,0 ----------------UAUGGCUUUUUAUUCCUAUGUGAU-------------------------------------------------- 3 0,1 -----------------AUGGCUUUUUAUUCCUAUGUGA--------------------------------------------------- 6 1,0 -----------------AUGGCUUUUUAUUCCUAUGUGAa-------------------------------------------------- 2 1,0 >hsa-mir-135a-2 5pM:23-45 Tumor agauaaauucacucuagugcuuUAUGGCUUUUUAUUCCUAUGUGAuaguaauaaagucucauguagggauggaagccaugaaauacauugugaaaaauca ----------------------UAUGGCUUUUUAUUCCUAUuu--------------------------------------------------------- 2 0,-4 ----------------------UAUGGCUUUUUAUUCCUAUGU--------------------------------------------------------- 40 0,-2 ----------------------UAUGGCUUUUUAUUCCUAUGUaa------------------------------------------------------- 3 0,-2 ----------------------UAUGGCUUUUUAUUCCUAUGUu-------------------------------------------------------- 2 0,-2 ----------------------UAUGGCUUUUUAUUCCUAUGUG-------------------------------------------------------- 74 0,-1 ----------------------UAUGGCUUUUUAUUCCUAUGUGu------------------------------------------------------- 18 0,-1 ----------------------UAUGGCUUUUUAUUCCUAUGUGA------------------------------------------------------- 449 0,0 ----------------------UAUGGCUUUUUAUUCCUAUGUGAa------------------------------------------------------ 26 0,0 ----------------------UAUGGCUUUUUAUUCCUAUGUGAU------------------------------------------------------ 3 0,1 -----------------------AUGGCUUUUUAUUCCUAUGUGA------------------------------------------------------- 6 1,0 -----------------------AUGGCUUUUUAUUCCUAUGUGAa------------------------------------------------------ 2 1,0 ------------------------------------------------------------AUGUAGGGAUGGAAGCCAUG-------------------- 2 ------------------------------------------------------------AUGUAGGGAUGGAAGCCAUGA------------------- 22 ------------------------------------------------------------AUGUAGGGAUGGAAGCCAUGAA------------------ 13 -------------------------------------------------------------UGUAGGGAUGGAAGCCAUGA------------------- 14 -------------------------------------------------------------UGUAGGGAUGGAAGCCAUGAA------------------ 19 -------------------------------------------------------------UGUAGGGAUGGAAGCCAUGAAg----------------- 3 -------------------------------------------------------------UGUAGGGAUGGAAGCCAUGAAu----------------- 6 -------------------------------------------------------------UGUAGGGAUGGAAGCCAUGAAA----------------- 36 -------------------------------------------------------------UGUAGGGAUGGAAGCCAUGAAAa---------------- 2 -------------------------------------------------------------UGUAGGGAUGGAAGCCAUGAAAU---------------- 2 --------------------------------------------------------------GUAGGGAUGGAAGCCAUGAAA----------------- 2 >hsa-mir-135b MA:16-38;mi:55-76 Tumor cacucugcuguggccUAUGGCUUUUCAUUCCUAUGUGAuugcugucccaaacucAUGUAGGGCUAAAAGCCAUGGGcuacagugaggggcgagcucc --------------CUAUGGCUUUUCAUUCCUAUGUG------------------------------------------------------------ 5 -1,-1 --------------CUAUGGCUUUUCAUUCCUAUGUGA----------------------------------------------------------- 13 -1,0 ---------------UAUGGCUUUUCAUUCCUA---------------------------------------------------------------- 4 0,-5 ---------------UAUGGCUUUUCAUUCCUAU--------------------------------------------------------------- 102 0,-4 ---------------UAUGGCUUUUCAUUCCUAUuu------------------------------------------------------------- 3 0,-4 ---------------UAUGGCUUUUCAUUCCUAUG-------------------------------------------------------------- 96 0,-3 ---------------UAUGGCUUUUCAUUCCUAUGa------------------------------------------------------------- 4 0,-3 ---------------UAUGGCUUUUCAUUCCUAUGU------------------------------------------------------------- 450 0,-2 ---------------UAUGGCUUUUCAUUCCUAUGUa------------------------------------------------------------ 7 0,-2 ---------------UAUGGCUUUUCAUUCCUAUGUaa----------------------------------------------------------- 6 0,-2 ---------------UAUGGCUUUUCAUUCCUAUGUu------------------------------------------------------------ 9 0,-2 ---------------UAUGGCUUUUCAUUCCUAUGUG------------------------------------------------------------ 1021 0,-1 ---------------UAUGGCUUUUCAUUCCUAUGUGc----------------------------------------------------------- 20 0,-1 ---------------UAUGGCUUUUCAUUCCUAUGUGu----------------------------------------------------------- 137 0,-1 ---------------UAUGGCUUUUCAUUCCUAUGUGA----------------------------------------------------------- 4206 0,0 ---------------UAUGGCUUUUCAUUCCUAUGUGAa---------------------------------------------------------- 27 0,0 ---------------UAUGGCUUUUCAUUCCUAUGUGAU---------------------------------------------------------- 4 0,1 ----------------AUGGCUUUUCAUUCCUAUGU------------------------------------------------------------- 3 1,-2 ----------------AUGGCUUUUCAUUCCUAUGUG------------------------------------------------------------ 27 1,-1 ----------------AUGGCUUUUCAUUCCUAUGUGA----------------------------------------------------------- 45 1,0 ------------------------------------------------------AUGUAGGGCUAAAAGCCAUGG---------------------- 7 0,-1 ------------------------------------------------------AUGUAGGGCUAAAAGCCAUGGG--------------------- 2 0,0 ------------------------------------------------------AUGUAGGGCUAAAAGCCAUGGGa-------------------- 2 0,0 ------------------------------------------------------AUGUAGGGCUAAAAGCCAUGGGu-------------------- 8 0,0 >hsa-mir-136 MA:15-37;mi:49-70 Tumor ugagcccucggaggACUCCAUUUGUUUUGAUGAUGGAuucuuaugcucCAUCAUCGUCUCAAAUGAGUCUucagaggguucu ------------GGACUCCAUUUGUUUUGAUGAU------------------------------------------------ 2 -2,-3 --------------ACUCCAUUUGUUUUGAUGA------------------------------------------------- 4 0,-4 --------------ACUCCAUUUGUUUUGAUGAU------------------------------------------------ 20 0,-3 --------------ACUCCAUUUGUUUUGAUGAUu----------------------------------------------- 2 0,-3 --------------ACUCCAUUUGUUUUGAUGAUG----------------------------------------------- 472 0,-2 --------------ACUCCAUUUGUUUUGAUGAUGa---------------------------------------------- 15 0,-2 --------------ACUCCAUUUGUUUUGAUGAUGaa--------------------------------------------- 2 0,-2 --------------ACUCCAUUUGUUUUGAUGAUGu---------------------------------------------- 10 0,-2 --------------ACUCCAUUUGUUUUGAUGAUGG---------------------------------------------- 2083 0,-1 --------------ACUCCAUUUGUUUUGAUGAUGGc--------------------------------------------- 4 0,-1 --------------ACUCCAUUUGUUUUGAUGAUGGu--------------------------------------------- 4 0,-1 --------------ACUCCAUUUGUUUUGAUGAUGGA--------------------------------------------- 2323 0,0 --------------ACUCCAUUUGUUUUGAUGAUGGAa-------------------------------------------- 106 0,0 ---------------CUCCAUUUGUUUUGAUGAUGG---------------------------------------------- 6 1,-1 ---------------CUCCAUUUGUUUUGAUGAUGGA--------------------------------------------- 33 1,0 ---------------CUCCAUUUGUUUUGAUGAUGGAa-------------------------------------------- 2 1,0 ------------------------------------------------CAUCAUCGUCUCAAAUGAGU-------------- 23 0,-2 ------------------------------------------------CAUCAUCGUCUCAAAUGAGUC------------- 44 0,-1 ------------------------------------------------CAUCAUCGUCUCAAAUGAGUCa------------ 6 0,-1 ------------------------------------------------CAUCAUCGUCUCAAAUGAGUCU------------ 386 0,0 ------------------------------------------------CAUCAUCGUCUCAAAUGAGUCUU----------- 2 0,1 -------------------------------------------------AUCAUCGUCUCAAAUGAG--------------- 2 1,-3 -------------------------------------------------AUCAUCGUCUCAAAUGAGU-------------- 15 1,-2 -------------------------------------------------AUCAUCGUCUCAAAUGAGUC------------- 46 1,-1 -------------------------------------------------AUCAUCGUCUCAAAUGAGUCa------------ 9 1,-1 -------------------------------------------------AUCAUCGUCUCAAAUGAGUCU------------ 826 1,0 -------------------------------------------------AUCAUCGUCUCAAAUGAGUCUU----------- 28 1,1 --------------------------------------------------UCAUCGUCUCAAAUGAGUCU------------ 9 2,0 --------------------------------------------------UCAUCGUCUCAAAUGAGUCUU----------- 25 2,1 --------------------------------------------------UCAUCGUCUCAAAUGAGUCUUu---------- 9 2,1 --------------------------------------------------UCAUCGUCUCAAAUGAGUCUUC---------- 2 2,2 >hsa-mir-137 3pM:59-81 Tumor gguccucugacucucuucggugacggguauucuuggguggauaauacggauuacguugUUAUUGCUUAAGAAUACGCGUAGucgaggagaguaccagcggca ----------------------------------------------------------UUAUUGCUUAAGAAUACGCGU----------------------- 21 0,-2 ----------------------------------------------------------UUAUUGCUUAAGAAUACGCGUA---------------------- 13 0,-1 ----------------------------------------------------------UUAUUGCUUAAGAAUACGCGUAa--------------------- 3 0,-1 ----------------------------------------------------------UUAUUGCUUAAGAAUACGCGUAu--------------------- 2 0,-1 ----------------------------------------------------------UUAUUGCUUAAGAAUACGCGUAG--------------------- 148 0,0 ----------------------------------------------------------UUAUUGCUUAAGAAUACGCGUAGU-------------------- 2 0,1 -----------------------------------------------------------UAUUGCUUAAGAAUACGCGUAG--------------------- 12 1,0 -----------------------------------------------------------UAUUGCUUAAGAAUACGCGUAGU-------------------- 10 1,1 ------------------------------------------------------------AUUGCUUAAGAAUACGCGUAG--------------------- 2 2,0 ------------------------------------------------------------AUUGCUUAAGAAUACGCGUAGU-------------------- 18 2,1 >hsa-mir-138-1 MA:23-45;mi:63-84 Tumor cccuggcauggugugguggggcAGCUGGUGUUGUGAAUCAGGCCGuugccaaucagagaacgGCUACUUCACAACACCAGGGCCacaccacacuacagg ----------------------AGCUGGUGUUGUGAAUCA----------------------------------------------------------- 14 0,-5 ----------------------AGCUGGUGUUGUGAAUCAG---------------------------------------------------------- 16 0,-4 ----------------------AGCUGGUGUUGUGAAUCAGa--------------------------------------------------------- 8 0,-4 ----------------------AGCUGGUGUUGUGAAUCAGG--------------------------------------------------------- 310 0,-3 ----------------------AGCUGGUGUUGUGAAUCAGGa-------------------------------------------------------- 35 0,-3 ----------------------AGCUGGUGUUGUGAAUCAGGaa------------------------------------------------------- 5 0,-3 ----------------------AGCUGGUGUUGUGAAUCAGGau------------------------------------------------------- 2 0,-3 ----------------------AGCUGGUGUUGUGAAUCAGGu-------------------------------------------------------- 13 0,-3 ----------------------AGCUGGUGUUGUGAAUCAGGC-------------------------------------------------------- 222 0,-2 ----------------------AGCUGGUGUUGUGAAUCAGGCa------------------------------------------------------- 34 0,-2 ----------------------AGCUGGUGUUGUGAAUCAGGCaa------------------------------------------------------ 7 0,-2 ----------------------AGCUGGUGUUGUGAAUCAGGCau------------------------------------------------------ 10 0,-2 ----------------------AGCUGGUGUUGUGAAUCAGGCu------------------------------------------------------- 3 0,-2 ----------------------AGCUGGUGUUGUGAAUCAGGCC------------------------------------------------------- 49 0,-1 ----------------------AGCUGGUGUUGUGAAUCAGGCCa------------------------------------------------------ 18 0,-1 ----------------------AGCUGGUGUUGUGAAUCAGGCCau----------------------------------------------------- 4 0,-1 ----------------------AGCUGGUGUUGUGAAUCAGGCCu------------------------------------------------------ 3 0,-1 ----------------------AGCUGGUGUUGUGAAUCAGGCCG------------------------------------------------------ 496 0,0 ----------------------AGCUGGUGUUGUGAAUCAGGCCGU----------------------------------------------------- 312 0,1 ----------------------AGCUGGUGUUGUGAAUCAGGCCGUa---------------------------------------------------- 7 0,1 ----------------------AGCUGGUGUUGUGAAUCAGGCCGUU---------------------------------------------------- 89 0,2 -----------------------GCUGGUGUUGUGAAUCAGG--------------------------------------------------------- 2 1,-3 -----------------------GCUGGUGUUGUGAAUCAGGC-------------------------------------------------------- 4 1,-2 -----------------------GCUGGUGUUGUGAAUCAGGCCG------------------------------------------------------ 5 1,0 -----------------------GCUGGUGUUGUGAAUCAGGCCGU----------------------------------------------------- 5 1,1 ------------------------------------------------------------CGGCUACUUCACAACACCAGG------------------ 2 -2,-3 --------------------------------------------------------------GCUACUUCACAACACCAGGGau--------------- 2 0,-2 --------------------------------------------------------------GCUACUUCACAACACCAGGGC---------------- 6 0,-1 --------------------------------------------------------------GCUACUUCACAACACCAGGGCu--------------- 2 0,-1 >hsa-mir-138-2 MA:10-32;mi:57-78 Tumor cguugcugcAGCUGGUGUUGUGAAUCAGGCCGacgagcagcgcauccucuuacccgGCUAUUUCACGACACCAGGGUUgcauca ---------AGCUGGUGUUGUGAAUCA--------------------------------------------------------- 14 0,-5 ---------AGCUGGUGUUGUGAAUCAG-------------------------------------------------------- 16 0,-4 ---------AGCUGGUGUUGUGAAUCAGa------------------------------------------------------- 8 0,-4 ---------AGCUGGUGUUGUGAAUCAGG------------------------------------------------------- 310 0,-3 ---------AGCUGGUGUUGUGAAUCAGGa------------------------------------------------------ 35 0,-3 ---------AGCUGGUGUUGUGAAUCAGGaa----------------------------------------------------- 5 0,-3 ---------AGCUGGUGUUGUGAAUCAGGau----------------------------------------------------- 2 0,-3 ---------AGCUGGUGUUGUGAAUCAGGu------------------------------------------------------ 13 0,-3 ---------AGCUGGUGUUGUGAAUCAGGC------------------------------------------------------ 222 0,-2 ---------AGCUGGUGUUGUGAAUCAGGCa----------------------------------------------------- 34 0,-2 ---------AGCUGGUGUUGUGAAUCAGGCaa---------------------------------------------------- 7 0,-2 ---------AGCUGGUGUUGUGAAUCAGGCau---------------------------------------------------- 10 0,-2 ---------AGCUGGUGUUGUGAAUCAGGCu----------------------------------------------------- 3 0,-2 ---------AGCUGGUGUUGUGAAUCAGGCC----------------------------------------------------- 49 0,-1 ---------AGCUGGUGUUGUGAAUCAGGCCa---------------------------------------------------- 18 0,-1 ---------AGCUGGUGUUGUGAAUCAGGCCau--------------------------------------------------- 4 0,-1 ---------AGCUGGUGUUGUGAAUCAGGCCu---------------------------------------------------- 3 0,-1 ---------AGCUGGUGUUGUGAAUCAGGCCG---------------------------------------------------- 496 0,0 ---------AGCUGGUGUUGUGAAUCAGGCCGA--------------------------------------------------- 150 0,1 ---------AGCUGGUGUUGUGAAUCAGGCCGAa-------------------------------------------------- 9 0,1 ---------AGCUGGUGUUGUGAAUCAGGCCGAu-------------------------------------------------- 10 0,1 ----------GCUGGUGUUGUGAAUCAGG------------------------------------------------------- 2 1,-3 ----------GCUGGUGUUGUGAAUCAGGC------------------------------------------------------ 4 1,-2 ----------GCUGGUGUUGUGAAUCAGGCCG---------------------------------------------------- 5 1,0 >hsa-mir-139 5p:7-28;3p:44-65 Tumor guguauUCUACAGUGCACGUGUCUCCAGuguggcucggaggcuGGAGACGCGGCCCUGUUGGAGUaac ------UCUACAGUGCACGUGUCU-------------------------------------------- 11 0,-4 ------UCUACAGUGCACGUGUCUC------------------------------------------- 2 0,-3 ------UCUACAGUGCACGUGUCUCC------------------------------------------ 55 0,-2 ------UCUACAGUGCACGUGUCUCCA----------------------------------------- 192 0,-1 ------UCUACAGUGCACGUGUCUCCAu---------------------------------------- 8 0,-1 ------UCUACAGUGCACGUGUCUCCAG---------------------------------------- 242 0,0 ------UCUACAGUGCACGUGUCUCCAGa--------------------------------------- 81 0,0 ------UCUACAGUGCACGUGUCUCCAGU--------------------------------------- 886 0,1 ------UCUACAGUGCACGUGUCUCCAGUa-------------------------------------- 2 0,1 ------UCUACAGUGCACGUGUCUCCAGUu-------------------------------------- 3 0,1 -------CUACAGUGCACGUGUCUCCAGU--------------------------------------- 8 1,1 ------------------------------------------UGGAGACGCGGCCCUGUUGGA----- 9 -1,-2 ------------------------------------------UGGAGACGCGGCCCUGUUGGAaa--- 4 -1,-2 ------------------------------------------UGGAGACGCGGCCCUGUUGGAG---- 9 -1,-1 ------------------------------------------UGGAGACGCGGCCCUGUUGGAGa--- 2 -1,-1 ------------------------------------------UGGAGACGCGGCCCUGUUGGAGU--- 28 -1,0 >hsa-mir-140 5p:23-44;3p:62-82 Tumor ugugucucucucuguguccugcCAGUGGUUUUACCCUAUGGUAGguuacgucaugcuguucUACCACAGGGUAGAACCACGGacaggauaccggggcacc ----------------------CAGUGGUUUUACCCUAUG------------------------------------------------------------ 21 0,-4 ----------------------CAGUGGUUUUACCCUAUGG----------------------------------------------------------- 213 0,-3 ----------------------CAGUGGUUUUACCCUAUGGa---------------------------------------------------------- 34 0,-3 ----------------------CAGUGGUUUUACCCUAUGGaa--------------------------------------------------------- 10 0,-3 ----------------------CAGUGGUUUUACCCUAUGGU---------------------------------------------------------- 1369 0,-2 ----------------------CAGUGGUUUUACCCUAUGGUg--------------------------------------------------------- 2 0,-2 ----------------------CAGUGGUUUUACCCUAUGGUu--------------------------------------------------------- 45 0,-2 ----------------------CAGUGGUUUUACCCUAUGGUA--------------------------------------------------------- 1567 0,-1 ----------------------CAGUGGUUUUACCCUAUGGUAa-------------------------------------------------------- 2010 0,-1 ----------------------CAGUGGUUUUACCCUAUGGUAaa------------------------------------------------------- 158 0,-1 ----------------------CAGUGGUUUUACCCUAUGGUAau------------------------------------------------------- 2 0,-1 ----------------------CAGUGGUUUUACCCUAUGGUAc-------------------------------------------------------- 9 0,-1 ----------------------CAGUGGUUUUACCCUAUGGUAu-------------------------------------------------------- 423 0,-1 ----------------------CAGUGGUUUUACCCUAUGGUAG-------------------------------------------------------- 7975 0,0 ----------------------CAGUGGUUUUACCCUAUGGUAGa------------------------------------------------------- 1322 0,0 ----------------------CAGUGGUUUUACCCUAUGGUAGaa------------------------------------------------------ 31 0,0 ----------------------CAGUGGUUUUACCCUAUGGUAGau------------------------------------------------------ 2 0,0 ----------------------CAGUGGUUUUACCCUAUGGUAGu------------------------------------------------------- 882 0,0 ----------------------CAGUGGUUUUACCCUAUGGUAGuu------------------------------------------------------ 6 0,0 ----------------------CAGUGGUUUUACCCUAUGGUAGG------------------------------------------------------- 124 0,1 ----------------------CAGUGGUUUUACCCUAUGGUAGGa------------------------------------------------------ 12 0,1 ----------------------CAGUGGUUUUACCCUAUGGUAGGU------------------------------------------------------ 4 0,2 -----------------------AGUGGUUUUACCCUAUGG----------------------------------------------------------- 2 1,-3 -----------------------AGUGGUUUUACCCUAUGGU---------------------------------------------------------- 31 1,-2 -----------------------AGUGGUUUUACCCUAUGGUA--------------------------------------------------------- 31 1,-1 -----------------------AGUGGUUUUACCCUAUGGUAa-------------------------------------------------------- 66 1,-1 -----------------------AGUGGUUUUACCCUAUGGUAu-------------------------------------------------------- 7 1,-1 -----------------------AGUGGUUUUACCCUAUGGUAG-------------------------------------------------------- 228 1,0 -----------------------AGUGGUUUUACCCUAUGGUAGa------------------------------------------------------- 30 1,0 -----------------------AGUGGUUUUACCCUAUGGUAGaa------------------------------------------------------ 2 1,0 -----------------------AGUGGUUUUACCCUAUGGUAGu------------------------------------------------------- 21 1,0 ------------------------GUGGUUUUACCCUAUGGUAG-------------------------------------------------------- 2 2,0 ------------------------------------------------------------CUACCACAGGGUAGAACCACGGA----------------- 2 -1,1 -------------------------------------------------------------UACCACAGGGUAGAACCA--------------------- 22 0,-3 -------------------------------------------------------------UACCACAGGGUAGAACCAC-------------------- 26 0,-2 -------------------------------------------------------------UACCACAGGGUAGAACCACG------------------- 715 0,-1 -------------------------------------------------------------UACCACAGGGUAGAACCACGa------------------ 48 0,-1 -------------------------------------------------------------UACCACAGGGUAGAACCACGaa----------------- 10 0,-1 -------------------------------------------------------------UACCACAGGGUAGAACCACGu------------------ 2 0,-1 -------------------------------------------------------------UACCACAGGGUAGAACCACGG------------------ 1641 0,0 -------------------------------------------------------------UACCACAGGGUAGAACCACGGc----------------- 29 0,0 -------------------------------------------------------------UACCACAGGGUAGAACCACGGg----------------- 6 0,0 -------------------------------------------------------------UACCACAGGGUAGAACCACGGu----------------- 116 0,0 -------------------------------------------------------------UACCACAGGGUAGAACCACGGuu---------------- 12 0,0 -------------------------------------------------------------UACCACAGGGUAGAACCACGGA----------------- 7075 0,1 -------------------------------------------------------------UACCACAGGGUAGAACCACGGAa---------------- 2629 0,1 -------------------------------------------------------------UACCACAGGGUAGAACCACGGAaa--------------- 534 0,1 -------------------------------------------------------------UACCACAGGGUAGAACCACGGAau--------------- 138 0,1 -------------------------------------------------------------UACCACAGGGUAGAACCACGGAg---------------- 90 0,1 -------------------------------------------------------------UACCACAGGGUAGAACCACGGAu---------------- 654 0,1 -------------------------------------------------------------UACCACAGGGUAGAACCACGGAuu--------------- 20 0,1 -------------------------------------------------------------UACCACAGGGUAGAACCACGGAC---------------- 2200 0,2 -------------------------------------------------------------UACCACAGGGUAGAACCACGGACg--------------- 18 0,2 -------------------------------------------------------------UACCACAGGGUAGAACCACGGACu--------------- 245 0,2 -------------------------------------------------------------UACCACAGGGUAGAACCACGGACA--------------- 521 0,3 --------------------------------------------------------------ACCACAGGGUAGAACCAC-------------------- 34 1,-2 --------------------------------------------------------------ACCACAGGGUAGAACCACG------------------- 182 1,-1 --------------------------------------------------------------ACCACAGGGUAGAACCACGa------------------ 44 1,-1 --------------------------------------------------------------ACCACAGGGUAGAACCACGaa----------------- 14 1,-1 --------------------------------------------------------------ACCACAGGGUAGAACCACGu------------------ 4 1,-1 --------------------------------------------------------------ACCACAGGGUAGAACCACGG------------------ 1062 1,0 --------------------------------------------------------------ACCACAGGGUAGAACCACGGc----------------- 27 1,0 --------------------------------------------------------------ACCACAGGGUAGAACCACGGg----------------- 4 1,0 --------------------------------------------------------------ACCACAGGGUAGAACCACGGu----------------- 95 1,0 --------------------------------------------------------------ACCACAGGGUAGAACCACGGuu---------------- 15 1,0 --------------------------------------------------------------ACCACAGGGUAGAACCACGGA----------------- 8935 1,1 --------------------------------------------------------------ACCACAGGGUAGAACCACGGAa---------------- 3821 1,1 --------------------------------------------------------------ACCACAGGGUAGAACCACGGAaa--------------- 2022 1,1 --------------------------------------------------------------ACCACAGGGUAGAACCACGGAau--------------- 417 1,1 --------------------------------------------------------------ACCACAGGGUAGAACCACGGAg---------------- 101 1,1 --------------------------------------------------------------ACCACAGGGUAGAACCACGGAu---------------- 1592 1,1 --------------------------------------------------------------ACCACAGGGUAGAACCACGGAuu--------------- 109 1,1 --------------------------------------------------------------ACCACAGGGUAGAACCACGGAC---------------- 8778 1,2 --------------------------------------------------------------ACCACAGGGUAGAACCACGGACc--------------- 4 1,2 --------------------------------------------------------------ACCACAGGGUAGAACCACGGACg--------------- 108 1,2 --------------------------------------------------------------ACCACAGGGUAGAACCACGGACu--------------- 1517 1,2 --------------------------------------------------------------ACCACAGGGUAGAACCACGGACuu-------------- 7 1,2 --------------------------------------------------------------ACCACAGGGUAGAACCACGGACA--------------- 3314 1,3 --------------------------------------------------------------ACCACAGGGUAGAACCACGGACAa-------------- 161 1,3 --------------------------------------------------------------ACCACAGGGUAGAACCACGGACAaa------------- 2 1,3 --------------------------------------------------------------ACCACAGGGUAGAACCACGGACAu-------------- 42 1,3 --------------------------------------------------------------ACCACAGGGUAGAACCACGGACAG-------------- 4 1,4 ---------------------------------------------------------------CCACAGGGUAGAACCACGG------------------ 6 2,0 ---------------------------------------------------------------CCACAGGGUAGAACCACGGu----------------- 2 2,0 ---------------------------------------------------------------CCACAGGGUAGAACCACGGA----------------- 190 2,1 ---------------------------------------------------------------CCACAGGGUAGAACCACGGAa---------------- 67 2,1 ---------------------------------------------------------------CCACAGGGUAGAACCACGGAaa--------------- 55 2,1 ---------------------------------------------------------------CCACAGGGUAGAACCACGGAau--------------- 6 2,1 ---------------------------------------------------------------CCACAGGGUAGAACCACGGAu---------------- 44 2,1 ---------------------------------------------------------------CCACAGGGUAGAACCACGGAC---------------- 282 2,2 ---------------------------------------------------------------CCACAGGGUAGAACCACGGACu--------------- 65 2,2 ---------------------------------------------------------------CCACAGGGUAGAACCACGGACA--------------- 144 2,3 ---------------------------------------------------------------CCACAGGGUAGAACCACGGACAa-------------- 7 2,3 >hsa-mir-141 mi:17-38;MA:59-80 Tumor cggccggcccugggucCAUCUUCCAGUACAGUGUUGGAuggucuaauugugaagcuccUAACACUGUCUGGUAAAGAUGGcucccggguggguuc ----------------CAUCUUCCAGUACAGUGUUG----------------------------------------------------------- 8 0,-2 ----------------CAUCUUCCAGUACAGUGUUGu---------------------------------------------------------- 2 0,-2 ----------------CAUCUUCCAGUACAGUGUUGG---------------------------------------------------------- 450 0,-1 ----------------CAUCUUCCAGUACAGUGUUGGc--------------------------------------------------------- 6 0,-1 ----------------CAUCUUCCAGUACAGUGUUGGu--------------------------------------------------------- 2 0,-1 ----------------CAUCUUCCAGUACAGUGUUGGA--------------------------------------------------------- 1795 0,0 ----------------CAUCUUCCAGUACAGUGUUGGAa-------------------------------------------------------- 98 0,0 ----------------CAUCUUCCAGUACAGUGUUGGAaa------------------------------------------------------- 10 0,0 ----------------CAUCUUCCAGUACAGUGUUGGAU-------------------------------------------------------- 58 0,1 ----------------CAUCUUCCAGUACAGUGUUGGAUu------------------------------------------------------- 4 0,1 ----------------CAUCUUCCAGUACAGUGUUGGAUuu------------------------------------------------------ 2 0,1 -----------------AUCUUCCAGUACAGUGUUGG---------------------------------------------------------- 8 1,-1 -----------------AUCUUCCAGUACAGUGUUGGc--------------------------------------------------------- 2 1,-1 -----------------AUCUUCCAGUACAGUGUUGGA--------------------------------------------------------- 41 1,0 -----------------AUCUUCCAGUACAGUGUUGGAU-------------------------------------------------------- 2 1,1 ---------------------------------------------------------CUAACACUGUCUGGUAAA-------------------- 2 -1,-5 ---------------------------------------------------------CUAACACUGUCUGGUAAAGA------------------ 29 -1,-3 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAa----------------- 2 -1,-3 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAaa---------------- 2 -1,-3 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAU----------------- 156 -1,-2 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAUa---------------- 25 -1,-2 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAUG---------------- 653 -1,-1 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAUGa--------------- 10 -1,-1 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAUGG--------------- 736 -1,0 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAUGGa-------------- 47 -1,0 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAUGGu-------------- 15 -1,0 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAUGGC-------------- 870 -1,1 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAUGGCa------------- 19 -1,1 ---------------------------------------------------------CUAACACUGUCUGGUAAAGAUGGCU------------- 52 -1,2 ----------------------------------------------------------UAACACUGUCUGGUAAAG------------------- 2011 0,-4 ----------------------------------------------------------UAACACUGUCUGGUAAAGc------------------ 2 0,-4 ----------------------------------------------------------UAACACUGUCUGGUAAAGu------------------ 47 0,-4 ----------------------------------------------------------UAACACUGUCUGGUAAAGuu----------------- 11 0,-4 ----------------------------------------------------------UAACACUGUCUGGUAAAGA------------------ 4352 0,-3 ----------------------------------------------------------UAACACUGUCUGGUAAAGAa----------------- 814 0,-3 ----------------------------------------------------------UAACACUGUCUGGUAAAGAaa---------------- 1105 0,-3 ----------------------------------------------------------UAACACUGUCUGGUAAAGAau---------------- 15 0,-3 ----------------------------------------------------------UAACACUGUCUGGUAAAGAc----------------- 12 0,-3 ----------------------------------------------------------UAACACUGUCUGGUAAAGAg----------------- 25 0,-3 ----------------------------------------------------------UAACACUGUCUGGUAAAGAU----------------- 14497 0,-2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUa---------------- 3853 0,-2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUaa--------------- 240 0,-2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUau--------------- 12 0,-2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUc---------------- 18 0,-2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUu---------------- 549 0,-2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUuu--------------- 12 0,-2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUG---------------- 65241 0,-1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGa--------------- 4744 0,-1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGaa-------------- 134 0,-1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGau-------------- 18 0,-1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGc--------------- 119 0,-1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGu--------------- 2912 0,-1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGuu-------------- 451 0,-1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGG--------------- 198384 0,0 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGa-------------- 15742 0,0 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGaa------------- 294 0,0 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGau------------- 179 0,0 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGg-------------- 188 0,0 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGu-------------- 10380 0,0 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGuu------------- 100 0,0 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGC-------------- 178244 0,1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGCa------------- 6261 0,1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGCaa------------ 360 0,1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGCau------------ 1438 0,1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGCc------------- 161 0,1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGCg------------- 301 0,1 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGCU------------- 18154 0,2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGCUa------------ 84 0,2 ----------------------------------------------------------UAACACUGUCUGGUAAAGAUGGCUu------------ 1054 0,2 -----------------------------------------------------------AACACUGUCUGGUAAAGA------------------ 108 1,-3 -----------------------------------------------------------AACACUGUCUGGUAAAGAa----------------- 17 1,-3 -----------------------------------------------------------AACACUGUCUGGUAAAGAaa---------------- 27 1,-3 -----------------------------------------------------------AACACUGUCUGGUAAAGAU----------------- 484 1,-2 -----------------------------------------------------------AACACUGUCUGGUAAAGAUa---------------- 131 1,-2 -----------------------------------------------------------AACACUGUCUGGUAAAGAUaa--------------- 5 1,-2 -----------------------------------------------------------AACACUGUCUGGUAAAGAUu---------------- 11 1,-2 -----------------------------------------------------------AACACUGUCUGGUAAAGAUG---------------- 2526 1,-1 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGa--------------- 165 1,-1 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGc--------------- 3 1,-1 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGu--------------- 99 1,-1 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGuu-------------- 15 1,-1 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGG--------------- 7999 1,0 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGGa-------------- 641 1,0 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGGu-------------- 409 1,0 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGGC-------------- 7612 1,1 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGGCa------------- 215 1,1 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGGCaa------------ 4 1,1 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGGCau------------ 33 1,1 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGGCg------------- 2 1,1 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGGCU------------- 786 1,2 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGGCUau----------- 2 1,2 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGGCUu------------ 26 1,2 -----------------------------------------------------------AACACUGUCUGGUAAAGAUGGCUuu----------- 7 1,2 ------------------------------------------------------------ACACUGUCUGGUAAAGAU----------------- 22 2,-2 ------------------------------------------------------------ACACUGUCUGGUAAAGAUa---------------- 2 2,-2 ------------------------------------------------------------ACACUGUCUGGUAAAGAUG---------------- 112 2,-1 ------------------------------------------------------------ACACUGUCUGGUAAAGAUGa--------------- 6 2,-1 ------------------------------------------------------------ACACUGUCUGGUAAAGAUGu--------------- 2 2,-1 ------------------------------------------------------------ACACUGUCUGGUAAAGAUGuu-------------- 2 2,-1 ------------------------------------------------------------ACACUGUCUGGUAAAGAUGG--------------- 412 2,0 ------------------------------------------------------------ACACUGUCUGGUAAAGAUGGa-------------- 15 2,0 ------------------------------------------------------------ACACUGUCUGGUAAAGAUGGu-------------- 8 2,0 ------------------------------------------------------------ACACUGUCUGGUAAAGAUGGC-------------- 393 2,1 ------------------------------------------------------------ACACUGUCUGGUAAAGAUGGCU------------- 26 2,2 ------------------------------------------------------------ACACUGUCUGGUAAAGAUGGCUu------------ 2 2,2 >hsa-mir-142 5p:16-36;3p:52-74 Tumor gacagugcagucaccCAUAAAGUAGAAAGCACUACUaacagcacuggagggUGUAGUGUUUCCUACUUUAUGGAugaguguacugug -------------CCCAUAAAGUAGAAAGCA-------------------------------------------------------- 925 -2,-5 -------------CCCAUAAAGUAGAAAGCAa------------------------------------------------------- 1190 -2,-5 -------------CCCAUAAAGUAGAAAGCAaa------------------------------------------------------ 151 -2,-5 -------------CCCAUAAAGUAGAAAGCAau------------------------------------------------------ 53 -2,-5 -------------CCCAUAAAGUAGAAAGCAg------------------------------------------------------- 8 -2,-5 -------------CCCAUAAAGUAGAAAGCAuu------------------------------------------------------ 21 -2,-5 -------------CCCAUAAAGUAGAAAGCAC------------------------------------------------------- 1105 -2,-4 -------------CCCAUAAAGUAGAAAGCACa------------------------------------------------------ 56 -2,-4 -------------CCCAUAAAGUAGAAAGCACaa----------------------------------------------------- 3 -2,-4 -------------CCCAUAAAGUAGAAAGCACc------------------------------------------------------ 15 -2,-4 -------------CCCAUAAAGUAGAAAGCACg------------------------------------------------------ 6 -2,-4 -------------CCCAUAAAGUAGAAAGCACU------------------------------------------------------ 23370 -2,-3 -------------CCCAUAAAGUAGAAAGCACUc----------------------------------------------------- 6 -2,-3 -------------CCCAUAAAGUAGAAAGCACUg----------------------------------------------------- 4 -2,-3 -------------CCCAUAAAGUAGAAAGCACUu----------------------------------------------------- 8 -2,-3 -------------CCCAUAAAGUAGAAAGCACUuu---------------------------------------------------- 2 -2,-3 -------------CCCAUAAAGUAGAAAGCACUA----------------------------------------------------- 12913 -2,-2 -------------CCCAUAAAGUAGAAAGCACUAa---------------------------------------------------- 1280 -2,-2 -------------CCCAUAAAGUAGAAAGCACUAaa--------------------------------------------------- 94 -2,-2 -------------CCCAUAAAGUAGAAAGCACUAg---------------------------------------------------- 36 -2,-2 -------------CCCAUAAAGUAGAAAGCACUAu---------------------------------------------------- 1651 -2,-2 -------------CCCAUAAAGUAGAAAGCACUAuu--------------------------------------------------- 26 -2,-2 -------------CCCAUAAAGUAGAAAGCACUAC---------------------------------------------------- 7206 -2,-1 -------------CCCAUAAAGUAGAAAGCACUACa--------------------------------------------------- 558 -2,-1 -------------CCCAUAAAGUAGAAAGCACUACc--------------------------------------------------- 259 -2,-1 -------------CCCAUAAAGUAGAAAGCACUACg--------------------------------------------------- 10 -2,-1 -------------CCCAUAAAGUAGAAAGCACUACU--------------------------------------------------- 277 -2,0 --------------CCAUAAAGUAGAAAGCAC------------------------------------------------------- 30 -1,-4 --------------CCAUAAAGUAGAAAGCACU------------------------------------------------------ 960 -1,-3 --------------CCAUAAAGUAGAAAGCACUA----------------------------------------------------- 544 -1,-2 --------------CCAUAAAGUAGAAAGCACUAa---------------------------------------------------- 24 -1,-2 --------------CCAUAAAGUAGAAAGCACUAu---------------------------------------------------- 48 -1,-2 --------------CCAUAAAGUAGAAAGCACUAuu--------------------------------------------------- 2 -1,-2 --------------CCAUAAAGUAGAAAGCACUAC---------------------------------------------------- 322 -1,-1 --------------CCAUAAAGUAGAAAGCACUACa--------------------------------------------------- 15 -1,-1 --------------CCAUAAAGUAGAAAGCACUACc--------------------------------------------------- 2 -1,-1 --------------CCAUAAAGUAGAAAGCACUACU--------------------------------------------------- 125 -1,0 --------------CCAUAAAGUAGAAAGCACUACUA-------------------------------------------------- 18 -1,1 --------------CCAUAAAGUAGAAAGCACUACUAu------------------------------------------------- 2 -1,1 ---------------CAUAAAGUAGAAAGCACU------------------------------------------------------ 2567 0,-3 ---------------CAUAAAGUAGAAAGCACUc----------------------------------------------------- 5 0,-3 ---------------CAUAAAGUAGAAAGCACUg----------------------------------------------------- 6 0,-3 ---------------CAUAAAGUAGAAAGCACUu----------------------------------------------------- 8 0,-3 ---------------CAUAAAGUAGAAAGCACUA----------------------------------------------------- 8960 0,-2 ---------------CAUAAAGUAGAAAGCACUAa---------------------------------------------------- 1587 0,-2 ---------------CAUAAAGUAGAAAGCACUAaa--------------------------------------------------- 496 0,-2 ---------------CAUAAAGUAGAAAGCACUAau--------------------------------------------------- 186 0,-2 ---------------CAUAAAGUAGAAAGCACUAg---------------------------------------------------- 53 0,-2 ---------------CAUAAAGUAGAAAGCACUAu---------------------------------------------------- 342 0,-2 ---------------CAUAAAGUAGAAAGCACUAuu--------------------------------------------------- 201 0,-2 ---------------CAUAAAGUAGAAAGCACUAC---------------------------------------------------- 7313 0,-1 ---------------CAUAAAGUAGAAAGCACUACa--------------------------------------------------- 1238 0,-1 ---------------CAUAAAGUAGAAAGCACUACaa-------------------------------------------------- 140 0,-1 ---------------CAUAAAGUAGAAAGCACUACc--------------------------------------------------- 151 0,-1 ---------------CAUAAAGUAGAAAGCACUACg--------------------------------------------------- 125 0,-1 ---------------CAUAAAGUAGAAAGCACUACU--------------------------------------------------- 89961 0,0 ---------------CAUAAAGUAGAAAGCACUACUc-------------------------------------------------- 53 0,0 ---------------CAUAAAGUAGAAAGCACUACUg-------------------------------------------------- 4 0,0 ---------------CAUAAAGUAGAAAGCACUACUu-------------------------------------------------- 124 0,0 ---------------CAUAAAGUAGAAAGCACUACUuu------------------------------------------------- 3 0,0 ---------------CAUAAAGUAGAAAGCACUACUA-------------------------------------------------- 18091 0,1 ---------------CAUAAAGUAGAAAGCACUACUAc------------------------------------------------- 8 0,1 ---------------CAUAAAGUAGAAAGCACUACUAg------------------------------------------------- 102 0,1 ---------------CAUAAAGUAGAAAGCACUACUAu------------------------------------------------- 2319 0,1 ---------------CAUAAAGUAGAAAGCACUACUAuu------------------------------------------------ 10 0,1 ---------------CAUAAAGUAGAAAGCACUACUAA------------------------------------------------- 1683 0,2 ---------------CAUAAAGUAGAAAGCACUACUAAa------------------------------------------------ 89 0,2 ---------------CAUAAAGUAGAAAGCACUACUAAaa----------------------------------------------- 2 0,2 ---------------CAUAAAGUAGAAAGCACUACUAAg------------------------------------------------ 4 0,2 ---------------CAUAAAGUAGAAAGCACUACUAAu------------------------------------------------ 6 0,2 ---------------CAUAAAGUAGAAAGCACUACUAAC------------------------------------------------ 2 0,3 ----------------AUAAAGUAGAAAGCACUA----------------------------------------------------- 723 1,-2 ----------------AUAAAGUAGAAAGCACUAa---------------------------------------------------- 159 1,-2 ----------------AUAAAGUAGAAAGCACUAaa--------------------------------------------------- 106 1,-2 ----------------AUAAAGUAGAAAGCACUAau--------------------------------------------------- 19 1,-2 ----------------AUAAAGUAGAAAGCACUAg---------------------------------------------------- 4 1,-2 ----------------AUAAAGUAGAAAGCACUAu---------------------------------------------------- 45 1,-2 ----------------AUAAAGUAGAAAGCACUAuu--------------------------------------------------- 8 1,-2 ----------------AUAAAGUAGAAAGCACUAC---------------------------------------------------- 619 1,-1 ----------------AUAAAGUAGAAAGCACUACa--------------------------------------------------- 173 1,-1 ----------------AUAAAGUAGAAAGCACUACaa-------------------------------------------------- 6 1,-1 ----------------AUAAAGUAGAAAGCACUACc--------------------------------------------------- 10 1,-1 ----------------AUAAAGUAGAAAGCACUACg--------------------------------------------------- 2 1,-1 ----------------AUAAAGUAGAAAGCACUACU--------------------------------------------------- 11094 1,0 ----------------AUAAAGUAGAAAGCACUACUc-------------------------------------------------- 6 1,0 ----------------AUAAAGUAGAAAGCACUACUu-------------------------------------------------- 6 1,0 ----------------AUAAAGUAGAAAGCACUACUA-------------------------------------------------- 2668 1,1 ----------------AUAAAGUAGAAAGCACUACUAc------------------------------------------------- 3 1,1 ----------------AUAAAGUAGAAAGCACUACUAg------------------------------------------------- 39 1,1 ----------------AUAAAGUAGAAAGCACUACUAu------------------------------------------------- 409 1,1 ----------------AUAAAGUAGAAAGCACUACUAuu------------------------------------------------ 2 1,1 ----------------AUAAAGUAGAAAGCACUACUAA------------------------------------------------- 3774 1,2 ----------------AUAAAGUAGAAAGCACUACUAAa------------------------------------------------ 308 1,2 ----------------AUAAAGUAGAAAGCACUACUAAg------------------------------------------------ 27 1,2 ----------------AUAAAGUAGAAAGCACUACUAAu------------------------------------------------ 107 1,2 ----------------AUAAAGUAGAAAGCACUACUAAC------------------------------------------------ 4 1,3 -----------------UAAAGUAGAAAGCACUACU--------------------------------------------------- 39 2,0 -----------------UAAAGUAGAAAGCACUACUA-------------------------------------------------- 14 2,1 -----------------UAAAGUAGAAAGCACUACUAA------------------------------------------------- 23 2,2 ---------------------------------------------------UGUAGUGUUUCCUACUUU------------------ 1282 0,-5 ---------------------------------------------------UGUAGUGUUUCCUACUUUA----------------- 154 0,-4 ---------------------------------------------------UGUAGUGUUUCCUACUUUAa---------------- 15 0,-4 ---------------------------------------------------UGUAGUGUUUCCUACUUUAaa--------------- 4 0,-4 ---------------------------------------------------UGUAGUGUUUCCUACUUUAU---------------- 2964 0,-3 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUa--------------- 15 0,-3 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUaa-------------- 14 0,-3 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUu--------------- 103 0,-3 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUuu-------------- 106 0,-3 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUG--------------- 5590 0,-2 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGa-------------- 4508 0,-2 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGaa------------- 620 0,-2 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGau------------- 2 0,-2 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGc-------------- 24 0,-2 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGu-------------- 796 0,-2 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGuu------------- 14 0,-2 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGG-------------- 57199 0,-1 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGGc------------- 257 0,-1 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGGg------------- 89 0,-1 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGGu------------- 2814 0,-1 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGGuu------------ 32 0,-1 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGGA------------- 56395 0,0 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGGAa------------ 3455 0,0 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGGAaa----------- 275 0,0 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGGAau----------- 13 0,0 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGGAc------------ 19 0,0 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGGAg------------ 46 0,0 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGGAU------------ 218 0,1 ---------------------------------------------------UGUAGUGUUUCCUACUUUAUGGAUu----------- 2 0,1 ----------------------------------------------------GUAGUGUUUCCUACUUUA----------------- 145 1,-4 ----------------------------------------------------GUAGUGUUUCCUACUUUAU---------------- 5170 1,-3 ----------------------------------------------------GUAGUGUUUCCUACUUUAUu--------------- 29 1,-3 ----------------------------------------------------GUAGUGUUUCCUACUUUAUuu-------------- 34 1,-3 ----------------------------------------------------GUAGUGUUUCCUACUUUAUG--------------- 3883 1,-2 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGa-------------- 529 1,-2 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGaa------------- 249 1,-2 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGau------------- 2 1,-2 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGc-------------- 8 1,-2 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGu-------------- 699 1,-2 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGuu------------- 19 1,-2 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGG-------------- 29141 1,-1 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGc------------- 458 1,-1 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGg------------- 100 1,-1 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGu------------- 1326 1,-1 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGuu------------ 31 1,-1 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGA------------- 77158 1,0 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGAa------------ 15547 1,0 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGAaa----------- 1516 1,0 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGAau----------- 113 1,0 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGAc------------ 116 1,0 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGAg------------ 283 1,0 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGAU------------ 1766 1,1 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGAUa----------- 14 1,1 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGAUc----------- 2 1,1 ----------------------------------------------------GUAGUGUUUCCUACUUUAUGGAUu----------- 71 1,1 -----------------------------------------------------UAGUGUUUCCUACUUUAU---------------- 55 2,-3 -----------------------------------------------------UAGUGUUUCCUACUUUAUG--------------- 38 2,-2 -----------------------------------------------------UAGUGUUUCCUACUUUAUGa-------------- 39 2,-2 -----------------------------------------------------UAGUGUUUCCUACUUUAUGaa------------- 5 2,-2 -----------------------------------------------------UAGUGUUUCCUACUUUAUGu-------------- 8 2,-2 -----------------------------------------------------UAGUGUUUCCUACUUUAUGG-------------- 343 2,-1 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGc------------- 8 2,-1 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGu------------- 24 2,-1 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGuu------------ 10 2,-1 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGA------------- 2201 2,0 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGAa------------ 1043 2,0 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGAaa----------- 320 2,0 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGAau----------- 26 2,0 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGAc------------ 4 2,0 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGAg------------ 4 2,0 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGAU------------ 334 2,1 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGAUa----------- 7 2,1 -----------------------------------------------------UAGUGUUUCCUACUUUAUGGAUu----------- 2 2,1 >hsa-mir-143 mi:27-48;MA:61-81 Tumor gcgcagcgcccugucucccagccugaGGUGCAGUGCUGCAUCUCUGGUcaguugggagucUGAGAUGAAGCACUGUAGCUCaggaagagagaaguuguucugcagc -------------------------AGGUGCAGUGCUGCAUCUCU------------------------------------------------------------- 4 -1,-3 -------------------------AGGUGCAGUGCUGCAUCUCUG------------------------------------------------------------ 74 -1,-2 -------------------------AGGUGCAGUGCUGCAUCUCUGa----------------------------------------------------------- 58 -1,-2 -------------------------AGGUGCAGUGCUGCAUCUCUGu----------------------------------------------------------- 10 -1,-2 -------------------------AGGUGCAGUGCUGCAUCUCUGG----------------------------------------------------------- 489 -1,-1 -------------------------AGGUGCAGUGCUGCAUCUCUGGa---------------------------------------------------------- 383 -1,-1 -------------------------AGGUGCAGUGCUGCAUCUCUGGaa--------------------------------------------------------- 34 -1,-1 -------------------------AGGUGCAGUGCUGCAUCUCUGGau--------------------------------------------------------- 10 -1,-1 -------------------------AGGUGCAGUGCUGCAUCUCUGGU---------------------------------------------------------- 66 -1,0 -------------------------AGGUGCAGUGCUGCAUCUCUGGUa--------------------------------------------------------- 2 -1,0 --------------------------GGUGCAGUGCUGCAUCUC-------------------------------------------------------------- 18 0,-4 --------------------------GGUGCAGUGCUGCAUCUCU------------------------------------------------------------- 73 0,-3 --------------------------GGUGCAGUGCUGCAUCUCUG------------------------------------------------------------ 256 0,-2 --------------------------GGUGCAGUGCUGCAUCUCUGa----------------------------------------------------------- 590 0,-2 --------------------------GGUGCAGUGCUGCAUCUCUGaa---------------------------------------------------------- 41 0,-2 --------------------------GGUGCAGUGCUGCAUCUCUGau---------------------------------------------------------- 8 0,-2 --------------------------GGUGCAGUGCUGCAUCUCUGc----------------------------------------------------------- 4 0,-2 --------------------------GGUGCAGUGCUGCAUCUCUGu----------------------------------------------------------- 242 0,-2 --------------------------GGUGCAGUGCUGCAUCUCUGuu---------------------------------------------------------- 2 0,-2 --------------------------GGUGCAGUGCUGCAUCUCUGG----------------------------------------------------------- 12377 0,-1 --------------------------GGUGCAGUGCUGCAUCUCUGGa---------------------------------------------------------- 2958 0,-1 --------------------------GGUGCAGUGCUGCAUCUCUGGaa--------------------------------------------------------- 1052 0,-1 --------------------------GGUGCAGUGCUGCAUCUCUGGau--------------------------------------------------------- 290 0,-1 --------------------------GGUGCAGUGCUGCAUCUCUGGc---------------------------------------------------------- 29 0,-1 --------------------------GGUGCAGUGCUGCAUCUCUGGU---------------------------------------------------------- 3783 0,0 --------------------------GGUGCAGUGCUGCAUCUCUGGUa--------------------------------------------------------- 679 0,0 --------------------------GGUGCAGUGCUGCAUCUCUGGUaa-------------------------------------------------------- 146 0,0 --------------------------GGUGCAGUGCUGCAUCUCUGGUau-------------------------------------------------------- 187 0,0 --------------------------GGUGCAGUGCUGCAUCUCUGGUg--------------------------------------------------------- 7 0,0 --------------------------GGUGCAGUGCUGCAUCUCUGGUu--------------------------------------------------------- 367 0,0 --------------------------GGUGCAGUGCUGCAUCUCUGGUuu-------------------------------------------------------- 48 0,0 --------------------------GGUGCAGUGCUGCAUCUCUGGUC--------------------------------------------------------- 238 0,1 --------------------------GGUGCAGUGCUGCAUCUCUGGUCu-------------------------------------------------------- 48 0,1 --------------------------GGUGCAGUGCUGCAUCUCUGGUCA-------------------------------------------------------- 28 0,2 ---------------------------GUGCAGUGCUGCAUCUCUGGa---------------------------------------------------------- 2 1,-1 ----------------------------------------------------------UCUGAGAUGAAGCACUGUAGCU-------------------------- 34 -2,-1 ----------------------------------------------------------UCUGAGAUGAAGCACUGUAGCUC------------------------- 36 -2,0 ----------------------------------------------------------UCUGAGAUGAAGCACUGUAGCUCu------------------------ 27 -2,0 ----------------------------------------------------------UCUGAGAUGAAGCACUGUAGCUCA------------------------ 2 -2,1 -----------------------------------------------------------CUGAGAUGAAGCACUGUA----------------------------- 2 -1,-4 -----------------------------------------------------------CUGAGAUGAAGCACUGUAa---------------------------- 2 -1,-4 -----------------------------------------------------------CUGAGAUGAAGCACUGUAG---------------------------- 84 -1,-3 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGa--------------------------- 2 -1,-3 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGu--------------------------- 2 -1,-3 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGC--------------------------- 136 -1,-2 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCa-------------------------- 2 -1,-2 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCaa------------------------- 2 -1,-2 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCU-------------------------- 1139 -1,-1 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUa------------------------- 87 -1,-1 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUaa------------------------ 15 -1,-1 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUau------------------------ 12 -1,-1 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUg------------------------- 2 -1,-1 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUu------------------------- 61 -1,-1 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUuu------------------------ 24 -1,-1 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUC------------------------- 885 -1,0 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUCc------------------------ 2 -1,0 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUCu------------------------ 1180 -1,0 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUCuu----------------------- 91 -1,0 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUCA------------------------ 226 -1,1 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUCAa----------------------- 2 -1,1 -----------------------------------------------------------CUGAGAUGAAGCACUGUAGCUCAu----------------------- 4 -1,1 ------------------------------------------------------------UGAGAUGAAGCACUGUAG---------------------------- 8909 0,-3 ------------------------------------------------------------UGAGAUGAAGCACUGUAGa--------------------------- 2058 0,-3 ------------------------------------------------------------UGAGAUGAAGCACUGUAGaa-------------------------- 627 0,-3 ------------------------------------------------------------UGAGAUGAAGCACUGUAGau-------------------------- 309 0,-3 ------------------------------------------------------------UGAGAUGAAGCACUGUAGg--------------------------- 3 0,-3 ------------------------------------------------------------UGAGAUGAAGCACUGUAGu--------------------------- 214 0,-3 ------------------------------------------------------------UGAGAUGAAGCACUGUAGuu-------------------------- 204 0,-3 ------------------------------------------------------------UGAGAUGAAGCACUGUAGC--------------------------- 9700 0,-2 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCa-------------------------- 2184 0,-2 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCaa------------------------- 1250 0,-2 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCau------------------------- 91 0,-2 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCc-------------------------- 216 0,-2 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCg-------------------------- 76 0,-2 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCU-------------------------- 121220 0,-1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUa------------------------- 8775 0,-1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUaa------------------------ 2075 0,-1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUau------------------------ 1243 0,-1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUg------------------------- 329 0,-1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUu------------------------- 10554 0,-1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUuu------------------------ 6086 0,-1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUC------------------------- 165106 0,0 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCc------------------------ 1898 0,0 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCg------------------------ 566 0,0 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCu------------------------ 220452 0,0 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCuu----------------------- 24690 0,0 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCA------------------------ 46525 0,1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAa----------------------- 2755 0,1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAaa---------------------- 67 0,1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAau---------------------- 27 0,1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAc----------------------- 19 0,1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAu----------------------- 2413 0,1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAuu---------------------- 72 0,1 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAG----------------------- 243 0,2 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAGa---------------------- 2 0,2 ------------------------------------------------------------UGAGAUGAAGCACUGUAGCUCAGu---------------------- 2 0,2 -------------------------------------------------------------GAGAUGAAGCACUGUAGC--------------------------- 235 1,-2 -------------------------------------------------------------GAGAUGAAGCACUGUAGCa-------------------------- 40 1,-2 -------------------------------------------------------------GAGAUGAAGCACUGUAGCaa------------------------- 11 1,-2 -------------------------------------------------------------GAGAUGAAGCACUGUAGCc-------------------------- 2 1,-2 -------------------------------------------------------------GAGAUGAAGCACUGUAGCU-------------------------- 2765 1,-1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUa------------------------- 240 1,-1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUaa------------------------ 30 1,-1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUau------------------------ 8 1,-1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUu------------------------- 231 1,-1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUuu------------------------ 150 1,-1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUC------------------------- 5887 1,0 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUCc------------------------ 33 1,0 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUCg------------------------ 10 1,0 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUCu------------------------ 7683 1,0 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUCuu----------------------- 853 1,0 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUCA------------------------ 1432 1,1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUCAa----------------------- 60 1,1 -------------------------------------------------------------GAGAUGAAGCACUGUAGCUCAu----------------------- 33 1,1 --------------------------------------------------------------AGAUGAAGCACUGUAGCU-------------------------- 90 2,-1 --------------------------------------------------------------AGAUGAAGCACUGUAGCUa------------------------- 6 2,-1 --------------------------------------------------------------AGAUGAAGCACUGUAGCUu------------------------- 4 2,-1 --------------------------------------------------------------AGAUGAAGCACUGUAGCUuu------------------------ 2 2,-1 --------------------------------------------------------------AGAUGAAGCACUGUAGCUC------------------------- 235 2,0 --------------------------------------------------------------AGAUGAAGCACUGUAGCUCu------------------------ 355 2,0 --------------------------------------------------------------AGAUGAAGCACUGUAGCUCuu----------------------- 22 2,0 --------------------------------------------------------------AGAUGAAGCACUGUAGCUCA------------------------ 29 2,1 --------------------------------------------------------------AGAUGAAGCACUGUAGCUCAu----------------------- 2 2,1 >hsa-mir-144 mi:15-36;MA:52-71 Tumor uggggcccuggcugGGAUAUCAUCAUAUACUGUAAGuuugcgaugagacacUACAGUAUAGAUGAUGUACUaguccgggcaccccc --------------GGAUAUCAUCAUAUACUG------------------------------------------------------ 2 0,-4 --------------GGAUAUCAUCAUAUACUGU----------------------------------------------------- 3 0,-3 --------------GGAUAUCAUCAUAUACUGUA---------------------------------------------------- 51 0,-2 --------------GGAUAUCAUCAUAUACUGUAA--------------------------------------------------- 43 0,-1 --------------GGAUAUCAUCAUAUACUGUAAu-------------------------------------------------- 2 0,-1 --------------GGAUAUCAUCAUAUACUGUAAG-------------------------------------------------- 523 0,0 --------------GGAUAUCAUCAUAUACUGUAAGa------------------------------------------------- 6 0,0 --------------GGAUAUCAUCAUAUACUGUAAGU------------------------------------------------- 816 0,1 --------------GGAUAUCAUCAUAUACUGUAAGUa------------------------------------------------ 2 0,1 --------------GGAUAUCAUCAUAUACUGUAAGUU------------------------------------------------ 32 0,2 ---------------GAUAUCAUCAUAUACUGUAAG-------------------------------------------------- 12 1,0 ---------------GAUAUCAUCAUAUACUGUAAGU------------------------------------------------- 54 1,1 ---------------GAUAUCAUCAUAUACUGUAAGUU------------------------------------------------ 26 1,2 ---------------GAUAUCAUCAUAUACUGUAAGUUU----------------------------------------------- 3 1,3 --------------------------------------------------CUACAGUAUAGAUGAUGU------------------ 2 -1,-3 --------------------------------------------------CUACAGUAUAGAUGAUGUA----------------- 216 -1,-2 --------------------------------------------------CUACAGUAUAGAUGAUGUAC---------------- 420 -1,-1 --------------------------------------------------CUACAGUAUAGAUGAUGUACU--------------- 1291 -1,0 --------------------------------------------------CUACAGUAUAGAUGAUGUACUu-------------- 2 -1,0 ---------------------------------------------------UACAGUAUAGAUGAUGUA----------------- 737 0,-2 ---------------------------------------------------UACAGUAUAGAUGAUGUAa---------------- 25 0,-2 ---------------------------------------------------UACAGUAUAGAUGAUGUAau--------------- 58 0,-2 ---------------------------------------------------UACAGUAUAGAUGAUGUAuu--------------- 11 0,-2 ---------------------------------------------------UACAGUAUAGAUGAUGUAC---------------- 2344 0,-1 ---------------------------------------------------UACAGUAUAGAUGAUGUACc--------------- 2 0,-1 ---------------------------------------------------UACAGUAUAGAUGAUGUACU--------------- 7977 0,0 ---------------------------------------------------UACAGUAUAGAUGAUGUACUu-------------- 11 0,0 ---------------------------------------------------UACAGUAUAGAUGAUGUACUuu------------- 2 0,0 ---------------------------------------------------UACAGUAUAGAUGAUGUACUA-------------- 52 0,1 ---------------------------------------------------UACAGUAUAGAUGAUGUACUAa------------- 3 0,1 ---------------------------------------------------UACAGUAUAGAUGAUGUACUAu------------- 2 0,1 ---------------------------------------------------UACAGUAUAGAUGAUGUACUAG------------- 2 0,2 ----------------------------------------------------ACAGUAUAGAUGAUGUAC---------------- 51 1,-1 ----------------------------------------------------ACAGUAUAGAUGAUGUACU--------------- 268 1,0 -----------------------------------------------------CAGUAUAGAUGAUGUACU--------------- 6 2,0 >hsa-mir-145 MA:16-38;mi:54-75 Tumor caccuuguccucacgGUCCAGUUUUCCCAGGAAUCCCUuagaugcuaagauggGGAUUCCUGGAAAUACUGUUCUugaggucaugguu --------------GGUCCAGUUUUCCCAGGAAU------------------------------------------------------ 13 -1,-4 --------------GGUCCAGUUUUCCCAGGAAUC----------------------------------------------------- 4 -1,-3 --------------GGUCCAGUUUUCCCAGGAAUCC---------------------------------------------------- 12 -1,-2 --------------GGUCCAGUUUUCCCAGGAAUCCC--------------------------------------------------- 8 -1,-1 --------------GGUCCAGUUUUCCCAGGAAUCCCU-------------------------------------------------- 16 -1,0 ---------------GUCCAGUUUUCCCAGGAA------------------------------------------------------- 1045 0,-5 ---------------GUCCAGUUUUCCCAGGAAa------------------------------------------------------ 2466 0,-5 ---------------GUCCAGUUUUCCCAGGAAaa----------------------------------------------------- 418 0,-5 ---------------GUCCAGUUUUCCCAGGAAau----------------------------------------------------- 20 0,-5 ---------------GUCCAGUUUUCCCAGGAAc------------------------------------------------------ 24 0,-5 ---------------GUCCAGUUUUCCCAGGAAg------------------------------------------------------ 93 0,-5 ---------------GUCCAGUUUUCCCAGGAAU------------------------------------------------------ 22887 0,-4 ---------------GUCCAGUUUUCCCAGGAAUa----------------------------------------------------- 381 0,-4 ---------------GUCCAGUUUUCCCAGGAAUaa---------------------------------------------------- 133 0,-4 ---------------GUCCAGUUUUCCCAGGAAUau---------------------------------------------------- 7 0,-4 ---------------GUCCAGUUUUCCCAGGAAUg----------------------------------------------------- 8 0,-4 ---------------GUCCAGUUUUCCCAGGAAUu----------------------------------------------------- 243 0,-4 ---------------GUCCAGUUUUCCCAGGAAUuu---------------------------------------------------- 4 0,-4 ---------------GUCCAGUUUUCCCAGGAAUC----------------------------------------------------- 16184 0,-3 ---------------GUCCAGUUUUCCCAGGAAUCa---------------------------------------------------- 1901 0,-3 ---------------GUCCAGUUUUCCCAGGAAUCaa--------------------------------------------------- 94 0,-3 ---------------GUCCAGUUUUCCCAGGAAUCau--------------------------------------------------- 2 0,-3 ---------------GUCCAGUUUUCCCAGGAAUCg---------------------------------------------------- 136 0,-3 ---------------GUCCAGUUUUCCCAGGAAUCu---------------------------------------------------- 592 0,-3 ---------------GUCCAGUUUUCCCAGGAAUCC---------------------------------------------------- 33111 0,-2 ---------------GUCCAGUUUUCCCAGGAAUCCa--------------------------------------------------- 1893 0,-2 ---------------GUCCAGUUUUCCCAGGAAUCCaa-------------------------------------------------- 61 0,-2 ---------------GUCCAGUUUUCCCAGGAAUCCau-------------------------------------------------- 362 0,-2 ---------------GUCCAGUUUUCCCAGGAAUCCg--------------------------------------------------- 43 0,-2 ---------------GUCCAGUUUUCCCAGGAAUCCu--------------------------------------------------- 126 0,-2 ---------------GUCCAGUUUUCCCAGGAAUCCuu-------------------------------------------------- 221 0,-2 ---------------GUCCAGUUUUCCCAGGAAUCCC--------------------------------------------------- 30758 0,-1 ---------------GUCCAGUUUUCCCAGGAAUCCCa-------------------------------------------------- 3316 0,-1 ---------------GUCCAGUUUUCCCAGGAAUCCCaa------------------------------------------------- 18 0,-1 ---------------GUCCAGUUUUCCCAGGAAUCCCau------------------------------------------------- 235 0,-1 ---------------GUCCAGUUUUCCCAGGAAUCCCc-------------------------------------------------- 690 0,-1 ---------------GUCCAGUUUUCCCAGGAAUCCCg-------------------------------------------------- 145 0,-1 ---------------GUCCAGUUUUCCCAGGAAUCCCU-------------------------------------------------- 119115 0,0 ---------------GUCCAGUUUUCCCAGGAAUCCCUa------------------------------------------------- 694 0,0 ---------------GUCCAGUUUUCCCAGGAAUCCCUaa------------------------------------------------ 35 0,0 ---------------GUCCAGUUUUCCCAGGAAUCCCUau------------------------------------------------ 110 0,0 ---------------GUCCAGUUUUCCCAGGAAUCCCUc------------------------------------------------- 25 0,0 ---------------GUCCAGUUUUCCCAGGAAUCCCUg------------------------------------------------- 23 0,0 ---------------GUCCAGUUUUCCCAGGAAUCCCUU------------------------------------------------- 7563 0,1 ---------------GUCCAGUUUUCCCAGGAAUCCCUUu------------------------------------------------ 835 0,1 ---------------GUCCAGUUUUCCCAGGAAUCCCUUA------------------------------------------------ 59 0,2 ----------------UCCAGUUUUCCCAGGAAU------------------------------------------------------ 20 1,-4 ----------------UCCAGUUUUCCCAGGAAUC----------------------------------------------------- 13 1,-3 ----------------UCCAGUUUUCCCAGGAAUCC---------------------------------------------------- 48 1,-2 ----------------UCCAGUUUUCCCAGGAAUCCC--------------------------------------------------- 51 1,-1 ----------------UCCAGUUUUCCCAGGAAUCCCU-------------------------------------------------- 387 1,0 ----------------UCCAGUUUUCCCAGGAAUCCCUU------------------------------------------------- 34 1,1 ----------------UCCAGUUUUCCCAGGAAUCCCUUu------------------------------------------------ 2 1,1 -----------------CCAGUUUUCCCAGGAAUC----------------------------------------------------- 2 2,-3 -----------------CCAGUUUUCCCAGGAAUCCC--------------------------------------------------- 4 2,-1 -----------------CCAGUUUUCCCAGGAAUCCCU-------------------------------------------------- 24 2,0 -----------------------------------------------------GGAUUCCUGGAAAUACUGU---------------- 2 0,-3 -----------------------------------------------------GGAUUCCUGGAAAUACUGUU--------------- 53 0,-2 -----------------------------------------------------GGAUUCCUGGAAAUACUGUUa-------------- 2 0,-2 -----------------------------------------------------GGAUUCCUGGAAAUACUGUUC-------------- 233 0,-1 -----------------------------------------------------GGAUUCCUGGAAAUACUGUUCU------------- 1051 0,0 -----------------------------------------------------GGAUUCCUGGAAAUACUGUUCUa------------ 2 0,0 -----------------------------------------------------GGAUUCCUGGAAAUACUGUUCUU------------ 38 0,1 -----------------------------------------------------GGAUUCCUGGAAAUACUGUUCUUu----------- 2 0,1 ------------------------------------------------------GAUUCCUGGAAAUACUGUU--------------- 4 1,-2 ------------------------------------------------------GAUUCCUGGAAAUACUGUUC-------------- 31 1,-1 ------------------------------------------------------GAUUCCUGGAAAUACUGUUCU------------- 281 1,0 ------------------------------------------------------GAUUCCUGGAAAUACUGUUCUa------------ 66 1,0 ------------------------------------------------------GAUUCCUGGAAAUACUGUUCUaa----------- 4 1,0 ------------------------------------------------------GAUUCCUGGAAAUACUGUUCUau----------- 10 1,0 ------------------------------------------------------GAUUCCUGGAAAUACUGUUCUU------------ 283 1,1 ------------------------------------------------------GAUUCCUGGAAAUACUGUUCUUa----------- 3 1,1 ------------------------------------------------------GAUUCCUGGAAAUACUGUUCUUu----------- 26 1,1 -------------------------------------------------------AUUCCUGGAAAUACUGUU--------------- 39 2,-2 -------------------------------------------------------AUUCCUGGAAAUACUGUUa-------------- 10 2,-2 -------------------------------------------------------AUUCCUGGAAAUACUGUUu-------------- 4 2,-2 -------------------------------------------------------AUUCCUGGAAAUACUGUUuu------------- 2 2,-2 -------------------------------------------------------AUUCCUGGAAAUACUGUUC-------------- 129 2,-1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCa------------- 13 2,-1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCaa------------ 4 2,-1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCU------------- 1514 2,0 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUa------------ 677 2,0 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUaa----------- 94 2,0 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUau----------- 99 2,0 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUc------------ 6 2,0 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUU------------ 2230 2,1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUUa----------- 27 2,1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUUaa---------- 2 2,1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUUau---------- 2 2,1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUUu----------- 161 2,1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUUuu---------- 2 2,1 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUUG----------- 17 2,2 -------------------------------------------------------AUUCCUGGAAAUACUGUUCUUGu---------- 3 2,2 >hsa-mir-1468 5pM:13-33 Tumor ggugggugguuuCUCCGUUUGCCUGUUUCGCUGaugugcauucaacucauucucagcaaaauaagcaaauggaaaauucguccauc ------------CUCCGUUUGCCUGUUUCGCUGA---------------------------------------------------- 34 0,1 >hsa-mir-146a MA:21-42;mi:57-78 Tumor ccgauguguauccucagcuuUGAGAACUGAAUUCCAUGGGUUgugucagugucagaCCUCUGAAAUUCAGUUCUUCAGcugggauaucucugucaucgu -------------------UUGAGAACUGAAUUCCAUGGGa---------------------------------------------------------- 2 -1,-2 -------------------UUGAGAACUGAAUUCCAUGGGU---------------------------------------------------------- 102 -1,-1 -------------------UUGAGAACUGAAUUCCAUGGGUa--------------------------------------------------------- 10 -1,-1 -------------------UUGAGAACUGAAUUCCAUGGGUau-------------------------------------------------------- 2 -1,-1 -------------------UUGAGAACUGAAUUCCAUGGGUU--------------------------------------------------------- 138 -1,0 -------------------UUGAGAACUGAAUUCCAUGGGUUau------------------------------------------------------- 2 -1,0 -------------------UUGAGAACUGAAUUCCAUGGGUUu-------------------------------------------------------- 14 -1,0 --------------------UGAGAACUGAAUUCCAUG------------------------------------------------------------- 138 0,-4 --------------------UGAGAACUGAAUUCCAUGa------------------------------------------------------------ 4 0,-4 --------------------UGAGAACUGAAUUCCAUGaa----------------------------------------------------------- 2 0,-4 --------------------UGAGAACUGAAUUCCAUGuu----------------------------------------------------------- 2 0,-4 --------------------UGAGAACUGAAUUCCAUGG------------------------------------------------------------ 363 0,-3 --------------------UGAGAACUGAAUUCCAUGGa----------------------------------------------------------- 8 0,-3 --------------------UGAGAACUGAAUUCCAUGGaa---------------------------------------------------------- 53 0,-3 --------------------UGAGAACUGAAUUCCAUGGau---------------------------------------------------------- 13 0,-3 --------------------UGAGAACUGAAUUCCAUGGuu---------------------------------------------------------- 13 0,-3 --------------------UGAGAACUGAAUUCCAUGGG----------------------------------------------------------- 552 0,-2 --------------------UGAGAACUGAAUUCCAUGGGa---------------------------------------------------------- 437 0,-2 --------------------UGAGAACUGAAUUCCAUGGGaa--------------------------------------------------------- 317 0,-2 --------------------UGAGAACUGAAUUCCAUGGGau--------------------------------------------------------- 72 0,-2 --------------------UGAGAACUGAAUUCCAUGGGc---------------------------------------------------------- 2 0,-2 --------------------UGAGAACUGAAUUCCAUGGGg---------------------------------------------------------- 8 0,-2 --------------------UGAGAACUGAAUUCCAUGGGU---------------------------------------------------------- 7416 0,-1 --------------------UGAGAACUGAAUUCCAUGGGUa--------------------------------------------------------- 806 0,-1 --------------------UGAGAACUGAAUUCCAUGGGUaa-------------------------------------------------------- 538 0,-1 --------------------UGAGAACUGAAUUCCAUGGGUau-------------------------------------------------------- 356 0,-1 --------------------UGAGAACUGAAUUCCAUGGGUc--------------------------------------------------------- 25 0,-1 --------------------UGAGAACUGAAUUCCAUGGGUg--------------------------------------------------------- 24 0,-1 --------------------UGAGAACUGAAUUCCAUGGGUU--------------------------------------------------------- 37378 0,0 --------------------UGAGAACUGAAUUCCAUGGGUUa-------------------------------------------------------- 1777 0,0 --------------------UGAGAACUGAAUUCCAUGGGUUaa------------------------------------------------------- 412 0,0 --------------------UGAGAACUGAAUUCCAUGGGUUau------------------------------------------------------- 523 0,0 --------------------UGAGAACUGAAUUCCAUGGGUUc-------------------------------------------------------- 5 0,0 --------------------UGAGAACUGAAUUCCAUGGGUUu-------------------------------------------------------- 8750 0,0 --------------------UGAGAACUGAAUUCCAUGGGUUuu------------------------------------------------------- 657 0,0 --------------------UGAGAACUGAAUUCCAUGGGUUG-------------------------------------------------------- 2005 0,1 --------------------UGAGAACUGAAUUCCAUGGGUUGa------------------------------------------------------- 551 0,1 --------------------UGAGAACUGAAUUCCAUGGGUUGaa------------------------------------------------------ 10 0,1 --------------------UGAGAACUGAAUUCCAUGGGUUGU------------------------------------------------------- 801 0,2 --------------------UGAGAACUGAAUUCCAUGGGUUGUu------------------------------------------------------ 2 0,2 ---------------------GAGAACUGAAUUCCAUGGG----------------------------------------------------------- 8 1,-2 ---------------------GAGAACUGAAUUCCAUGGGa---------------------------------------------------------- 7 1,-2 ---------------------GAGAACUGAAUUCCAUGGGaa--------------------------------------------------------- 5 1,-2 ---------------------GAGAACUGAAUUCCAUGGGc---------------------------------------------------------- 2 1,-2 ---------------------GAGAACUGAAUUCCAUGGGU---------------------------------------------------------- 312 1,-1 ---------------------GAGAACUGAAUUCCAUGGGUa--------------------------------------------------------- 9 1,-1 ---------------------GAGAACUGAAUUCCAUGGGUaa-------------------------------------------------------- 9 1,-1 ---------------------GAGAACUGAAUUCCAUGGGUau-------------------------------------------------------- 7 1,-1 ---------------------GAGAACUGAAUUCCAUGGGUU--------------------------------------------------------- 1683 1,0 ---------------------GAGAACUGAAUUCCAUGGGUUa-------------------------------------------------------- 89 1,0 ---------------------GAGAACUGAAUUCCAUGGGUUaa------------------------------------------------------- 11 1,0 ---------------------GAGAACUGAAUUCCAUGGGUUau------------------------------------------------------- 8 1,0 ---------------------GAGAACUGAAUUCCAUGGGUUu-------------------------------------------------------- 328 1,0 ---------------------GAGAACUGAAUUCCAUGGGUUuu------------------------------------------------------- 12 1,0 ---------------------GAGAACUGAAUUCCAUGGGUUG-------------------------------------------------------- 177 1,1 ---------------------GAGAACUGAAUUCCAUGGGUUGa------------------------------------------------------- 37 1,1 ---------------------GAGAACUGAAUUCCAUGGGUUGU------------------------------------------------------- 32 1,2 ----------------------AGAACUGAAUUCCAUGGGU---------------------------------------------------------- 5 2,-1 ----------------------AGAACUGAAUUCCAUGGGUU--------------------------------------------------------- 58 2,0 ----------------------AGAACUGAAUUCCAUGGGUUu-------------------------------------------------------- 12 2,0 ----------------------AGAACUGAAUUCCAUGGGUUG-------------------------------------------------------- 55 2,1 ----------------------AGAACUGAAUUCCAUGGGUUGa------------------------------------------------------- 6 2,1 ----------------------AGAACUGAAUUCCAUGGGUUGU------------------------------------------------------- 21 2,2 ------------------------------------------------------GACCUCUGAAAUUCAGUUCUU------------------------ 8 -2,-3 ------------------------------------------------------GACCUCUGAAAUUCAGUUCUUu----------------------- 2 -2,-3 ------------------------------------------------------GACCUCUGAAAUUCAGUUCUUC----------------------- 8 -2,-2 -------------------------------------------------------ACCUCUGAAAUUCAGUUCUU------------------------ 3 -1,-3 -------------------------------------------------------ACCUCUGAAAUUCAGUUCUUC----------------------- 8 -1,-2 -------------------------------------------------------ACCUCUGAAAUUCAGUUCUUCu---------------------- 2 -1,-2 -------------------------------------------------------ACCUCUGAAAUUCAGUUCUUCA---------------------- 20 -1,-1 --------------------------------------------------------CCUCUGAAAUUCAGUUCUUC----------------------- 6 0,-2 --------------------------------------------------------CCUCUGAAAUUCAGUUCUUCA---------------------- 19 0,-1 --------------------------------------------------------CCUCUGAAAUUCAGUUCUUCAG--------------------- 3 0,0 --------------------------------------------------------CCUCUGAAAUUCAGUUCUUCAGu-------------------- 8 0,0 ----------------------------------------------------------UCUGAAAUUCAGUUCUUCAGu-------------------- 3 2,0 >hsa-mir-146b 5p:9-30;3p:45-66 Tumor ccuggcacUGAGAACUGAAUUCCAUAGGCUgugagcucuagcaaUGCCCUGUGGACUCAGUUCUGGugcccgg -------CUGAGAACUGAAUUCCAU------------------------------------------------ 129 -1,-5 -------CUGAGAACUGAAUUCCAUAGGCU------------------------------------------- 49 -1,0 -------CUGAGAACUGAAUUCCAUAGGCUG------------------------------------------ 2 -1,1 -------CUGAGAACUGAAUUCCAUAGGCUGa----------------------------------------- 2 -1,1 -------CUGAGAACUGAAUUCCAUAGGCUGg----------------------------------------- 7 -1,1 -------CUGAGAACUGAAUUCCAUAGGCUGU----------------------------------------- 2 -1,2 --------UGAGAACUGAAUUCCAUA----------------------------------------------- 184 0,-4 --------UGAGAACUGAAUUCCAUAa---------------------------------------------- 4 0,-4 --------UGAGAACUGAAUUCCAUAaa--------------------------------------------- 2 0,-4 --------UGAGAACUGAAUUCCAUAG---------------------------------------------- 731 0,-3 --------UGAGAACUGAAUUCCAUAGa--------------------------------------------- 118 0,-3 --------UGAGAACUGAAUUCCAUAGaa-------------------------------------------- 31 0,-3 --------UGAGAACUGAAUUCCAUAGu--------------------------------------------- 4 0,-3 --------UGAGAACUGAAUUCCAUAGG--------------------------------------------- 2778 0,-2 --------UGAGAACUGAAUUCCAUAGGa-------------------------------------------- 681 0,-2 --------UGAGAACUGAAUUCCAUAGGaa------------------------------------------- 355 0,-2 --------UGAGAACUGAAUUCCAUAGGau------------------------------------------- 71 0,-2 --------UGAGAACUGAAUUCCAUAGGu-------------------------------------------- 54 0,-2 --------UGAGAACUGAAUUCCAUAGGuu------------------------------------------- 77 0,-2 --------UGAGAACUGAAUUCCAUAGGC-------------------------------------------- 2766 0,-1 --------UGAGAACUGAAUUCCAUAGGCa------------------------------------------- 979 0,-1 --------UGAGAACUGAAUUCCAUAGGCaa------------------------------------------ 192 0,-1 --------UGAGAACUGAAUUCCAUAGGCau------------------------------------------ 51 0,-1 --------UGAGAACUGAAUUCCAUAGGCc------------------------------------------- 22 0,-1 --------UGAGAACUGAAUUCCAUAGGCg------------------------------------------- 6 0,-1 --------UGAGAACUGAAUUCCAUAGGCU------------------------------------------- 27676 0,0 --------UGAGAACUGAAUUCCAUAGGCUa------------------------------------------ 904 0,0 --------UGAGAACUGAAUUCCAUAGGCUaa----------------------------------------- 80 0,0 --------UGAGAACUGAAUUCCAUAGGCUau----------------------------------------- 181 0,0 --------UGAGAACUGAAUUCCAUAGGCUc------------------------------------------ 3 0,0 --------UGAGAACUGAAUUCCAUAGGCUu------------------------------------------ 1095 0,0 --------UGAGAACUGAAUUCCAUAGGCUuu----------------------------------------- 84 0,0 --------UGAGAACUGAAUUCCAUAGGCUG------------------------------------------ 7537 0,1 --------UGAGAACUGAAUUCCAUAGGCUGa----------------------------------------- 1731 0,1 --------UGAGAACUGAAUUCCAUAGGCUGaa---------------------------------------- 29 0,1 --------UGAGAACUGAAUUCCAUAGGCUGau---------------------------------------- 8 0,1 --------UGAGAACUGAAUUCCAUAGGCUGc----------------------------------------- 36 0,1 --------UGAGAACUGAAUUCCAUAGGCUGg----------------------------------------- 2591 0,1 --------UGAGAACUGAAUUCCAUAGGCUGU----------------------------------------- 5758 0,2 --------UGAGAACUGAAUUCCAUAGGCUGUa---------------------------------------- 105 0,2 --------UGAGAACUGAAUUCCAUAGGCUGUu---------------------------------------- 137 0,2 ---------GAGAACUGAAUUCCAUAG---------------------------------------------- 12 1,-3 ---------GAGAACUGAAUUCCAUAGG--------------------------------------------- 60 1,-2 ---------GAGAACUGAAUUCCAUAGGa-------------------------------------------- 12 1,-2 ---------GAGAACUGAAUUCCAUAGGaa------------------------------------------- 5 1,-2 ---------GAGAACUGAAUUCCAUAGGC-------------------------------------------- 73 1,-1 ---------GAGAACUGAAUUCCAUAGGCa------------------------------------------- 24 1,-1 ---------GAGAACUGAAUUCCAUAGGCU------------------------------------------- 1026 1,0 ---------GAGAACUGAAUUCCAUAGGCUa------------------------------------------ 24 1,0 ---------GAGAACUGAAUUCCAUAGGCUau----------------------------------------- 2 1,0 ---------GAGAACUGAAUUCCAUAGGCUu------------------------------------------ 36 1,0 ---------GAGAACUGAAUUCCAUAGGCUG------------------------------------------ 267 1,1 ---------GAGAACUGAAUUCCAUAGGCUGa----------------------------------------- 39 1,1 ---------GAGAACUGAAUUCCAUAGGCUGg----------------------------------------- 54 1,1 ---------GAGAACUGAAUUCCAUAGGCUGU----------------------------------------- 131 1,2 ----------AGAACUGAAUUCCAUAGGCU------------------------------------------- 8 2,0 --------------------------------------------UGCCCUGUGGACUCAGUUCUGG------- 13 0,0 --------------------------------------------UGCCCUGUGGACUCAGUUCUGGU------ 69 0,1 --------------------------------------------UGCCCUGUGGACUCAGUUCUGGUa----- 4 0,1 ---------------------------------------------GCCCUGUGGACUCAGUUCU--------- 3 1,-2 ---------------------------------------------GCCCUGUGGACUCAGUUCUGG------- 39 1,0 ---------------------------------------------GCCCUGUGGACUCAGUUCUGGa------ 8 1,0 ---------------------------------------------GCCCUGUGGACUCAGUUCUGGU------ 240 1,1 ---------------------------------------------GCCCUGUGGACUCAGUUCUGGUa----- 20 1,1 ---------------------------------------------GCCCUGUGGACUCAGUUCUGGUaa---- 7 1,1 ---------------------------------------------GCCCUGUGGACUCAGUUCUGGUu----- 2 1,1 ----------------------------------------------CCCUGUGGACUCAGUUCUGGU------ 2 2,1 ----------------------------------------------CCCUGUGGACUCAGUUCUGGUu----- 2 2,1 >hsa-mir-147b 3pM:49-70 Tumor uauaaaucuaguggaaacauuucugcacaaacuagauucuggacaccaGUGUGCGGAAAUGCUUCUGCUAcauuuuuagg -----------UGGAAACAUUUCUGCACAA-------------------------------------------------- 2 -----------UGGAAACAUUUCUGCACAAAa------------------------------------------------ 2 -----------UGGAAACAUUUCUGCACAAAC------------------------------------------------ 4 -----------UGGAAACAUUUCUGCACAAACU----------------------------------------------- 42 -----------UGGAAACAUUUCUGCACAAACUAG--------------------------------------------- 3 -----------------------------------------------AGUGUGCGGAAAUGCUUCU-------------- 9 -1,-4 -----------------------------------------------AGUGUGCGGAAAUGCUUCUG------------- 13 -1,-3 -----------------------------------------------AGUGUGCGGAAAUGCUUCUGa------------ 6 -1,-3 -----------------------------------------------AGUGUGCGGAAAUGCUUCUGu------------ 8 -1,-3 -----------------------------------------------AGUGUGCGGAAAUGCUUCUGC------------ 18 -1,-2 -----------------------------------------------AGUGUGCGGAAAUGCUUCUGCa----------- 2 -1,-2 -----------------------------------------------AGUGUGCGGAAAUGCUUCUGCU----------- 253 -1,-1 -----------------------------------------------AGUGUGCGGAAAUGCUUCUGCUu---------- 33 -1,-1 -----------------------------------------------AGUGUGCGGAAAUGCUUCUGCUuu--------- 10 -1,-1 -----------------------------------------------AGUGUGCGGAAAUGCUUCUGCUA---------- 15 -1,0 -----------------------------------------------AGUGUGCGGAAAUGCUUCUGCUAa--------- 4 -1,0 -----------------------------------------------AGUGUGCGGAAAUGCUUCUGCUAaa-------- 2 -1,0 -----------------------------------------------AGUGUGCGGAAAUGCUUCUGCUAu--------- 7 -1,0 ------------------------------------------------GUGUGCGGAAAUGCUUCU-------------- 17 0,-4 ------------------------------------------------GUGUGCGGAAAUGCUUCUaa------------ 2 0,-4 ------------------------------------------------GUGUGCGGAAAUGCUUCUG------------- 86 0,-3 ------------------------------------------------GUGUGCGGAAAUGCUUCUGa------------ 57 0,-3 ------------------------------------------------GUGUGCGGAAAUGCUUCUGaa----------- 2 0,-3 ------------------------------------------------GUGUGCGGAAAUGCUUCUGu------------ 36 0,-3 ------------------------------------------------GUGUGCGGAAAUGCUUCUGuu----------- 4 0,-3 ------------------------------------------------GUGUGCGGAAAUGCUUCUGC------------ 99 0,-2 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCa----------- 10 0,-2 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCc----------- 2 0,-2 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCU----------- 1764 0,-1 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUc---------- 2 0,-1 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUg---------- 3 0,-1 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUu---------- 146 0,-1 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUuu--------- 27 0,-1 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUA---------- 531 0,0 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUAa--------- 132 0,0 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUAaa-------- 5 0,0 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUAau-------- 6 0,0 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUAg--------- 2 0,0 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUAu--------- 74 0,0 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUAuu-------- 10 0,0 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUAC--------- 91 0,1 ------------------------------------------------GUGUGCGGAAAUGCUUCUGCUACu-------- 3 0,1 -------------------------------------------------UGUGCGGAAAUGCUUCUGC------------ 4 1,-2 -------------------------------------------------UGUGCGGAAAUGCUUCUGCU----------- 47 1,-1 -------------------------------------------------UGUGCGGAAAUGCUUCUGCUA---------- 8 1,0 -------------------------------------------------UGUGCGGAAAUGCUUCUGCUAa--------- 2 1,0 -------------------------------------------------UGUGCGGAAAUGCUUCUGCUAC--------- 14 1,1 -------------------------------------------------UGUGCGGAAAUGCUUCUGCUACu-------- 6 1,1 >hsa-mir-148a mi:6-27;MA:44-65 Tumor gaggcAAAGUUCUGAGACACUCCGACUcugaguaugauagaagUCAGUGCACUACAGAACUUUGUcuc ----CAAAGUUCUGAGACACUCC--------------------------------------------- 2 -1,-4 ----CAAAGUUCUGAGACACUCCGA------------------------------------------- 74 -1,-2 ----CAAAGUUCUGAGACACUCCGAa------------------------------------------ 2 -1,-2 ----CAAAGUUCUGAGACACUCCGAC------------------------------------------ 3 -1,-1 ----CAAAGUUCUGAGACACUCCGACU----------------------------------------- 17 -1,0 -----AAAGUUCUGAGACACUCC--------------------------------------------- 4 0,-4 -----AAAGUUCUGAGACACUCCG-------------------------------------------- 78 0,-3 -----AAAGUUCUGAGACACUCCGc------------------------------------------- 6 0,-3 -----AAAGUUCUGAGACACUCCGu------------------------------------------- 2 0,-3 -----AAAGUUCUGAGACACUCCGA------------------------------------------- 1710 0,-2 -----AAAGUUCUGAGACACUCCGAa------------------------------------------ 4 0,-2 -----AAAGUUCUGAGACACUCCGAaa----------------------------------------- 5 0,-2 -----AAAGUUCUGAGACACUCCGAau----------------------------------------- 2 0,-2 -----AAAGUUCUGAGACACUCCGAu------------------------------------------ 2 0,-2 -----AAAGUUCUGAGACACUCCGAC------------------------------------------ 299 0,-1 -----AAAGUUCUGAGACACUCCGACa----------------------------------------- 83 0,-1 -----AAAGUUCUGAGACACUCCGACU----------------------------------------- 1460 0,0 -----AAAGUUCUGAGACACUCCGACUu---------------------------------------- 2 0,0 ------AAGUUCUGAGACACUCCGA------------------------------------------- 17 1,-2 ------AAGUUCUGAGACACUCCGAC------------------------------------------ 6 1,-1 ------AAGUUCUGAGACACUCCGACU----------------------------------------- 27 1,0 ------------------------------------------GUCAGUGCACUACAGAACUUU----- 4 -1,-2 ------------------------------------------GUCAGUGCACUACAGAACUUUG---- 17 -1,-1 ------------------------------------------GUCAGUGCACUACAGAACUUUGU--- 73 -1,0 -------------------------------------------UCAGUGCACUACAGAACU------- 2122 0,-4 -------------------------------------------UCAGUGCACUACAGAACUa------ 17 0,-4 -------------------------------------------UCAGUGCACUACAGAACUaa----- 6 0,-4 -------------------------------------------UCAGUGCACUACAGAACUau----- 6 0,-4 -------------------------------------------UCAGUGCACUACAGAACUc------ 3 0,-4 -------------------------------------------UCAGUGCACUACAGAACUg------ 2 0,-4 -------------------------------------------UCAGUGCACUACAGAACUU------ 9315 0,-3 -------------------------------------------UCAGUGCACUACAGAACUUa----- 134 0,-3 -------------------------------------------UCAGUGCACUACAGAACUUaa---- 4 0,-3 -------------------------------------------UCAGUGCACUACAGAACUUc----- 66 0,-3 -------------------------------------------UCAGUGCACUACAGAACUUg----- 35 0,-3 -------------------------------------------UCAGUGCACUACAGAACUUU----- 49913 0,-2 -------------------------------------------UCAGUGCACUACAGAACUUUa---- 395 0,-2 -------------------------------------------UCAGUGCACUACAGAACUUUaa--- 50 0,-2 -------------------------------------------UCAGUGCACUACAGAACUUUau--- 687 0,-2 -------------------------------------------UCAGUGCACUACAGAACUUUc---- 50 0,-2 -------------------------------------------UCAGUGCACUACAGAACUUUu---- 778 0,-2 -------------------------------------------UCAGUGCACUACAGAACUUUuu--- 1002 0,-2 -------------------------------------------UCAGUGCACUACAGAACUUUG---- 99015 0,-1 -------------------------------------------UCAGUGCACUACAGAACUUUGa--- 6952 0,-1 -------------------------------------------UCAGUGCACUACAGAACUUUGaa-- 104 0,-1 -------------------------------------------UCAGUGCACUACAGAACUUUGau-- 15 0,-1 -------------------------------------------UCAGUGCACUACAGAACUUUGc--- 819 0,-1 -------------------------------------------UCAGUGCACUACAGAACUUUGg--- 328 0,-1 -------------------------------------------UCAGUGCACUACAGAACUUUGU--- 358118 0,0 -------------------------------------------UCAGUGCACUACAGAACUUUGUa-- 2322 0,0 -------------------------------------------UCAGUGCACUACAGAACUUUGUaa- 296 0,0 -------------------------------------------UCAGUGCACUACAGAACUUUGUau- 116 0,0 -------------------------------------------UCAGUGCACUACAGAACUUUGUg-- 86 0,0 -------------------------------------------UCAGUGCACUACAGAACUUUGUu-- 11800 0,0 -------------------------------------------UCAGUGCACUACAGAACUUUGUuu- 838 0,0 -------------------------------------------UCAGUGCACUACAGAACUUUGUC-- 12133 0,1 -------------------------------------------UCAGUGCACUACAGAACUUUGUCa- 800 0,1 -------------------------------------------UCAGUGCACUACAGAACUUUGUCau 2 0,1 -------------------------------------------UCAGUGCACUACAGAACUUUGUCc- 6 0,1 -------------------------------------------UCAGUGCACUACAGAACUUUGUCg- 34 0,1 -------------------------------------------UCAGUGCACUACAGAACUUUGUCU- 3458 0,2 -------------------------------------------UCAGUGCACUACAGAACUUUGUCUu 14 0,2 --------------------------------------------CAGUGCACUACAGAACUU------ 36 1,-3 --------------------------------------------CAGUGCACUACAGAACUUU----- 216 1,-2 --------------------------------------------CAGUGCACUACAGAACUUUa---- 2 1,-2 --------------------------------------------CAGUGCACUACAGAACUUUu---- 13 1,-2 --------------------------------------------CAGUGCACUACAGAACUUUuu--- 25 1,-2 --------------------------------------------CAGUGCACUACAGAACUUUG---- 749 1,-1 --------------------------------------------CAGUGCACUACAGAACUUUGa--- 11 1,-1 --------------------------------------------CAGUGCACUACAGAACUUUGU--- 3003 1,0 --------------------------------------------CAGUGCACUACAGAACUUUGUa-- 4 1,0 --------------------------------------------CAGUGCACUACAGAACUUUGUu-- 29 1,0 --------------------------------------------CAGUGCACUACAGAACUUUGUC-- 77 1,1 --------------------------------------------CAGUGCACUACAGAACUUUGUCa- 4 1,1 --------------------------------------------CAGUGCACUACAGAACUUUGUCU- 18 1,2 ---------------------------------------------AGUGCACUACAGAACUUU----- 317 2,-2 ---------------------------------------------AGUGCACUACAGAACUUUau--- 10 2,-2 ---------------------------------------------AGUGCACUACAGAACUUUuu--- 7 2,-2 ---------------------------------------------AGUGCACUACAGAACUUUG---- 913 2,-1 ---------------------------------------------AGUGCACUACAGAACUUUGa--- 37 2,-1 ---------------------------------------------AGUGCACUACAGAACUUUGU--- 3648 2,0 ---------------------------------------------AGUGCACUACAGAACUUUGUa-- 6 2,0 ---------------------------------------------AGUGCACUACAGAACUUUGUaa- 2 2,0 ---------------------------------------------AGUGCACUACAGAACUUUGUu-- 92 2,0 ---------------------------------------------AGUGCACUACAGAACUUUGUC-- 88 2,1 ---------------------------------------------AGUGCACUACAGAACUUUGUCa- 2 2,1 ---------------------------------------------AGUGCACUACAGAACUUUGUCU- 14 2,2 >hsa-mir-148b mi:25-46;MA:63-84 Tumor caagcacgauuagcauuugaggugAAGUUCUGUUAUACACUCAGGCuguggcucucugaaagUCAGUGCAUCACAGAACUUUGUcucgaaagcuuucua -----------------------GAAGUUCUGUUAUACACUC--------------------------------------------------------- 2 -1,-4 -----------------------GAAGUUCUGUUAUACACUCA-------------------------------------------------------- 28 -1,-3 -----------------------GAAGUUCUGUUAUACACUCAG------------------------------------------------------- 30 -1,-2 -----------------------GAAGUUCUGUUAUACACUCAGG------------------------------------------------------ 301 -1,-1 -----------------------GAAGUUCUGUUAUACACUCAGGa----------------------------------------------------- 30 -1,-1 -----------------------GAAGUUCUGUUAUACACUCAGGu----------------------------------------------------- 2 -1,-1 -----------------------GAAGUUCUGUUAUACACUCAGGC----------------------------------------------------- 311 -1,0 -----------------------GAAGUUCUGUUAUACACUCAGGCa---------------------------------------------------- 13 -1,0 -----------------------GAAGUUCUGUUAUACACUCAGGCU---------------------------------------------------- 132 -1,1 ------------------------AAGUUCUGUUAUACACUCAGG------------------------------------------------------ 5 0,-1 ------------------------AAGUUCUGUUAUACACUCAGGC----------------------------------------------------- 11 0,0 ------------------------AAGUUCUGUUAUACACUCAGGCU---------------------------------------------------- 45 0,1 --------------------------GUUCUGUUAUACACUCAGGC----------------------------------------------------- 2 2,0 --------------------------------------------------------------UCAGUGCAUCACAGAACU------------------- 77 0,-4 --------------------------------------------------------------UCAGUGCAUCACAGAACUU------------------ 266 0,-3 --------------------------------------------------------------UCAGUGCAUCACAGAACUUa----------------- 6 0,-3 --------------------------------------------------------------UCAGUGCAUCACAGAACUUU----------------- 1963 0,-2 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUa---------------- 17 0,-2 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUaa--------------- 4 0,-2 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUau--------------- 50 0,-2 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUu---------------- 52 0,-2 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUuu--------------- 71 0,-2 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUG---------------- 7451 0,-1 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGa--------------- 876 0,-1 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGaa-------------- 12 0,-1 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGau-------------- 4 0,-1 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGc--------------- 46 0,-1 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGg--------------- 20 0,-1 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGU--------------- 39345 0,0 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGUa-------------- 641 0,0 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGUaa------------- 89 0,0 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGUau------------- 51 0,0 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGUg-------------- 26 0,0 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGUu-------------- 15159 0,0 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGUuu------------- 1701 0,0 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGUC-------------- 38 0,1 --------------------------------------------------------------UCAGUGCAUCACAGAACUUUGUCU------------- 2 0,2 ---------------------------------------------------------------CAGUGCAUCACAGAACUUU----------------- 9 1,-2 ---------------------------------------------------------------CAGUGCAUCACAGAACUUUG---------------- 31 1,-1 ---------------------------------------------------------------CAGUGCAUCACAGAACUUUGU--------------- 378 1,0 ---------------------------------------------------------------CAGUGCAUCACAGAACUUUGUu-------------- 81 1,0 ---------------------------------------------------------------CAGUGCAUCACAGAACUUUGUuu------------- 2 1,0 ----------------------------------------------------------------AGUGCAUCACAGAACUUU----------------- 3 2,-2 ----------------------------------------------------------------AGUGCAUCACAGAACUUUG---------------- 61 2,-1 ----------------------------------------------------------------AGUGCAUCACAGAACUUUGa--------------- 6 2,-1 ----------------------------------------------------------------AGUGCAUCACAGAACUUUGU--------------- 345 2,0 ----------------------------------------------------------------AGUGCAUCACAGAACUUUGUa-------------- 4 2,0 ----------------------------------------------------------------AGUGCAUCACAGAACUUUGUu-------------- 105 2,0 ----------------------------------------------------------------AGUGCAUCACAGAACUUUGUuu------------- 4 2,0 >hsa-mir-149 MA:15-37;mi:56-76 Tumor gccggcgcccgagcUCUGGCUCCGUGUCUUCACUCCCgugcuuguccgaggagggAGGGAGGGACGGGGGCUGUGCuggggcagcugga -------------CUCUGGCUCCGUGUCUUCACU------------------------------------------------------- 2 -1,-3 --------------UCUGGCUCCGUGUCUUCA--------------------------------------------------------- 35 0,-5 --------------UCUGGCUCCGUGUCUUCAa-------------------------------------------------------- 2 0,-5 --------------UCUGGCUCCGUGUCUUCAaa------------------------------------------------------- 3 0,-5 --------------UCUGGCUCCGUGUCUUCAC-------------------------------------------------------- 52 0,-4 --------------UCUGGCUCCGUGUCUUCACa------------------------------------------------------- 4 0,-4 --------------UCUGGCUCCGUGUCUUCACaa------------------------------------------------------ 3 0,-4 --------------UCUGGCUCCGUGUCUUCACU------------------------------------------------------- 4301 0,-3 --------------UCUGGCUCCGUGUCUUCACUa------------------------------------------------------ 29 0,-3 --------------UCUGGCUCCGUGUCUUCACUaa----------------------------------------------------- 12 0,-3 --------------UCUGGCUCCGUGUCUUCACUu------------------------------------------------------ 27 0,-3 --------------UCUGGCUCCGUGUCUUCACUuu----------------------------------------------------- 3 0,-3 --------------UCUGGCUCCGUGUCUUCACUC------------------------------------------------------ 1109 0,-2 --------------UCUGGCUCCGUGUCUUCACUCa----------------------------------------------------- 87 0,-2 --------------UCUGGCUCCGUGUCUUCACUCaa---------------------------------------------------- 4 0,-2 --------------UCUGGCUCCGUGUCUUCACUCu----------------------------------------------------- 115 0,-2 --------------UCUGGCUCCGUGUCUUCACUCC----------------------------------------------------- 1352 0,-1 --------------UCUGGCUCCGUGUCUUCACUCCa---------------------------------------------------- 21 0,-1 --------------UCUGGCUCCGUGUCUUCACUCCau--------------------------------------------------- 3 0,-1 --------------UCUGGCUCCGUGUCUUCACUCCu---------------------------------------------------- 33 0,-1 --------------UCUGGCUCCGUGUCUUCACUCCuu--------------------------------------------------- 2 0,-1 --------------UCUGGCUCCGUGUCUUCACUCCC---------------------------------------------------- 971 0,0 --------------UCUGGCUCCGUGUCUUCACUCCCa--------------------------------------------------- 19 0,0 --------------UCUGGCUCCGUGUCUUCACUCCCau-------------------------------------------------- 2 0,0 --------------UCUGGCUCCGUGUCUUCACUCCCu--------------------------------------------------- 111 0,0 --------------UCUGGCUCCGUGUCUUCACUCCCuu-------------------------------------------------- 9 0,0 ---------------CUGGCUCCGUGUCUUCACU------------------------------------------------------- 84 1,-3 ---------------CUGGCUCCGUGUCUUCACUC------------------------------------------------------ 24 1,-2 ---------------CUGGCUCCGUGUCUUCACUCC----------------------------------------------------- 19 1,-1 ---------------CUGGCUCCGUGUCUUCACUCCC---------------------------------------------------- 15 1,0 ----------------UGGCUCCGUGUCUUCACU------------------------------------------------------- 7 2,-3 ----------------UGGCUCCGUGUCUUCACUCCC---------------------------------------------------- 2 2,0 ------------------------------------------------------GAGGGAGGGACGGGGGCUGUG-------------- 2 -1,-1 ------------------------------------------------------GAGGGAGGGACGGGGGCUGUGu------------- 2 -1,-1 ------------------------------------------------------GAGGGAGGGACGGGGGCUGUGC------------- 9 -1,0 >hsa-mir-150 MA:16-37;mi:51-72 Tumor cuccccauggcccugUCUCCCAACCCUUGUACCAGUGcugggcucagaccCUGGUACAGGCCUGGGGGACAGggaccuggggac -------------UGUCUCCCAACCCUUGUAC---------------------------------------------------- 2 -2,-5 -------------UGUCUCCCAACCCUUGUACC--------------------------------------------------- 4 -2,-4 -------------UGUCUCCCAACCCUUGUACCA-------------------------------------------------- 7 -2,-3 -------------UGUCUCCCAACCCUUGUACCAG------------------------------------------------- 19 -2,-2 -------------UGUCUCCCAACCCUUGUACCAGa------------------------------------------------ 11 -2,-2 -------------UGUCUCCCAACCCUUGUACCAGU------------------------------------------------ 189 -2,-1 -------------UGUCUCCCAACCCUUGUACCAGUG----------------------------------------------- 27 -2,0 -------------UGUCUCCCAACCCUUGUACCAGUGu---------------------------------------------- 10 -2,0 --------------GUCUCCCAACCCUUGUACCAGU------------------------------------------------ 4 -1,-1 ---------------UCUCCCAACCCUUGUACC--------------------------------------------------- 469 0,-4 ---------------UCUCCCAACCCUUGUACCA-------------------------------------------------- 287 0,-3 ---------------UCUCCCAACCCUUGUACCAa------------------------------------------------- 8 0,-3 ---------------UCUCCCAACCCUUGUACCAau------------------------------------------------ 9 0,-3 ---------------UCUCCCAACCCUUGUACCAu------------------------------------------------- 2 0,-3 ---------------UCUCCCAACCCUUGUACCAG------------------------------------------------- 1220 0,-2 ---------------UCUCCCAACCCUUGUACCAGa------------------------------------------------ 181 0,-2 ---------------UCUCCCAACCCUUGUACCAGaa----------------------------------------------- 16 0,-2 ---------------UCUCCCAACCCUUGUACCAGc------------------------------------------------ 17 0,-2 ---------------UCUCCCAACCCUUGUACCAGg------------------------------------------------ 9 0,-2 ---------------UCUCCCAACCCUUGUACCAGU------------------------------------------------ 11339 0,-1 ---------------UCUCCCAACCCUUGUACCAGUa----------------------------------------------- 425 0,-1 ---------------UCUCCCAACCCUUGUACCAGUaa---------------------------------------------- 64 0,-1 ---------------UCUCCCAACCCUUGUACCAGUc----------------------------------------------- 12 0,-1 ---------------UCUCCCAACCCUUGUACCAGUu----------------------------------------------- 69 0,-1 ---------------UCUCCCAACCCUUGUACCAGUG----------------------------------------------- 21108 0,0 ---------------UCUCCCAACCCUUGUACCAGUGa---------------------------------------------- 6685 0,0 ---------------UCUCCCAACCCUUGUACCAGUGaa--------------------------------------------- 81 0,0 ---------------UCUCCCAACCCUUGUACCAGUGg---------------------------------------------- 60 0,0 ---------------UCUCCCAACCCUUGUACCAGUGu---------------------------------------------- 2931 0,0 ---------------UCUCCCAACCCUUGUACCAGUGuu--------------------------------------------- 16 0,0 ---------------UCUCCCAACCCUUGUACCAGUGC---------------------------------------------- 106 0,1 ----------------CUCCCAACCCUUGUACCAG------------------------------------------------- 2 1,-2 ----------------CUCCCAACCCUUGUACCAGU------------------------------------------------ 109 1,-1 ----------------CUCCCAACCCUUGUACCAGUG----------------------------------------------- 173 1,0 ----------------CUCCCAACCCUUGUACCAGUGa---------------------------------------------- 57 1,0 ----------------CUCCCAACCCUUGUACCAGUGu---------------------------------------------- 19 1,0 -----------------UCCCAACCCUUGUACCAGU------------------------------------------------ 9 2,-1 -----------------UCCCAACCCUUGUACCAGUG----------------------------------------------- 70 2,0 -----------------UCCCAACCCUUGUACCAGUGa---------------------------------------------- 12 2,0 -----------------UCCCAACCCUUGUACCAGUGu---------------------------------------------- 6 2,0 -------------------------------------------------CCUGGUACAGGCCUGGGGGAC-------------- 6 -1,-2 -------------------------------------------------CCUGGUACAGGCCUGGGGGACA------------- 4 -1,-1 --------------------------------------------------CUGGUACAGGCCUGGGGGA--------------- 6 0,-3 --------------------------------------------------CUGGUACAGGCCUGGGGGAa-------------- 2 0,-3 --------------------------------------------------CUGGUACAGGCCUGGGGGAC-------------- 29 0,-2 --------------------------------------------------CUGGUACAGGCCUGGGGGACu------------- 4 0,-2 --------------------------------------------------CUGGUACAGGCCUGGGGGACA------------- 108 0,-1 --------------------------------------------------CUGGUACAGGCCUGGGGGACAGG----------- 2 0,1 ---------------------------------------------------UGGUACAGGCCUGGGGGACA------------- 2 1,-1 >hsa-mir-151 5p:11-31;3p:47-67 Tumor uuuccugcccUCGAGGAGCUCACAGUCUAGUaugucucauccccuaCUAGACUGAAGCUCCUUGAGGacagggauggucauacucaccuc --------CCUCGAGGAGCUCACAGUCUAGU----------------------------------------------------------- 2 -2,0 ---------CUCGAGGAGCUCACAGUCU-------------------------------------------------------------- 6 -1,-3 ---------CUCGAGGAGCUCACAGUCUAu------------------------------------------------------------ 2 -1,-2 ---------CUCGAGGAGCUCACAGUCUAG------------------------------------------------------------ 102 -1,-1 ---------CUCGAGGAGCUCACAGUCUAGc----------------------------------------------------------- 2 -1,-1 ---------CUCGAGGAGCUCACAGUCUAGU----------------------------------------------------------- 1046 -1,0 ---------CUCGAGGAGCUCACAGUCUAGUu---------------------------------------------------------- 10 -1,0 ---------CUCGAGGAGCUCACAGUCUAGUA---------------------------------------------------------- 317 -1,1 ---------CUCGAGGAGCUCACAGUCUAGUAa--------------------------------------------------------- 36 -1,1 ---------CUCGAGGAGCUCACAGUCUAGUAU--------------------------------------------------------- 21 -1,2 ----------UCGAGGAGCUCACAGUCU-------------------------------------------------------------- 252 0,-3 ----------UCGAGGAGCUCACAGUCUu------------------------------------------------------------- 10 0,-3 ----------UCGAGGAGCUCACAGUCUA------------------------------------------------------------- 101 0,-2 ----------UCGAGGAGCUCACAGUCUAa------------------------------------------------------------ 24 0,-2 ----------UCGAGGAGCUCACAGUCUAau----------------------------------------------------------- 21 0,-2 ----------UCGAGGAGCUCACAGUCUAu------------------------------------------------------------ 13 0,-2 ----------UCGAGGAGCUCACAGUCUAuu----------------------------------------------------------- 22 0,-2 ----------UCGAGGAGCUCACAGUCUAG------------------------------------------------------------ 2299 0,-1 ----------UCGAGGAGCUCACAGUCUAGc----------------------------------------------------------- 16 0,-1 ----------UCGAGGAGCUCACAGUCUAGg----------------------------------------------------------- 16 0,-1 ----------UCGAGGAGCUCACAGUCUAGU----------------------------------------------------------- 23261 0,0 ----------UCGAGGAGCUCACAGUCUAGUc---------------------------------------------------------- 35 0,0 ----------UCGAGGAGCUCACAGUCUAGUg---------------------------------------------------------- 8 0,0 ----------UCGAGGAGCUCACAGUCUAGUu---------------------------------------------------------- 105 0,0 ----------UCGAGGAGCUCACAGUCUAGUuu--------------------------------------------------------- 7 0,0 ----------UCGAGGAGCUCACAGUCUAGUA---------------------------------------------------------- 9894 0,1 ----------UCGAGGAGCUCACAGUCUAGUAa--------------------------------------------------------- 3533 0,1 ----------UCGAGGAGCUCACAGUCUAGUAaa-------------------------------------------------------- 117 0,1 ----------UCGAGGAGCUCACAGUCUAGUAau-------------------------------------------------------- 21 0,1 ----------UCGAGGAGCUCACAGUCUAGUAc--------------------------------------------------------- 23 0,1 ----------UCGAGGAGCUCACAGUCUAGUAg--------------------------------------------------------- 90 0,1 ----------UCGAGGAGCUCACAGUCUAGUAU--------------------------------------------------------- 1339 0,2 ----------UCGAGGAGCUCACAGUCUAGUAUa-------------------------------------------------------- 3 0,2 ----------UCGAGGAGCUCACAGUCUAGUAUu-------------------------------------------------------- 8 0,2 ----------UCGAGGAGCUCACAGUCUAGUAUG-------------------------------------------------------- 6 0,3 ----------UCGAGGAGCUCACAGUCUAGUAUGU------------------------------------------------------- 2 0,4 -----------CGAGGAGCUCACAGUCUAG------------------------------------------------------------ 28 1,-1 -----------CGAGGAGCUCACAGUCUAGU----------------------------------------------------------- 569 1,0 -----------CGAGGAGCUCACAGUCUAGUA---------------------------------------------------------- 238 1,1 -----------CGAGGAGCUCACAGUCUAGUAa--------------------------------------------------------- 67 1,1 -----------CGAGGAGCUCACAGUCUAGUAU--------------------------------------------------------- 39 1,2 -----------CGAGGAGCUCACAGUCUAGUAUG-------------------------------------------------------- 12 1,3 ------------GAGGAGCUCACAGUCUAG------------------------------------------------------------ 11 2,-1 ------------GAGGAGCUCACAGUCUAGU----------------------------------------------------------- 222 2,0 ------------GAGGAGCUCACAGUCUAGUA---------------------------------------------------------- 66 2,1 ------------GAGGAGCUCACAGUCUAGUAa--------------------------------------------------------- 19 2,1 ------------GAGGAGCUCACAGUCUAGUAUG-------------------------------------------------------- 4 2,3 --------------------------------------------UACUAGACUGAAGCUCCUUG-------------------------- 23 -2,-3 --------------------------------------------UACUAGACUGAAGCUCCUUGu------------------------- 2 -2,-3 --------------------------------------------UACUAGACUGAAGCUCCUUGuu------------------------ 2 -2,-3 --------------------------------------------UACUAGACUGAAGCUCCUUGA------------------------- 418 -2,-2 --------------------------------------------UACUAGACUGAAGCUCCUUGAa------------------------ 28 -2,-2 --------------------------------------------UACUAGACUGAAGCUCCUUGAaa----------------------- 2 -2,-2 --------------------------------------------UACUAGACUGAAGCUCCUUGAu------------------------ 32 -2,-2 --------------------------------------------UACUAGACUGAAGCUCCUUGAuu----------------------- 2 -2,-2 --------------------------------------------UACUAGACUGAAGCUCCUUGAG------------------------ 1397 -2,-1 --------------------------------------------UACUAGACUGAAGCUCCUUGAGa----------------------- 319 -2,-1 --------------------------------------------UACUAGACUGAAGCUCCUUGAGaa---------------------- 3 -2,-1 --------------------------------------------UACUAGACUGAAGCUCCUUGAGau---------------------- 2 -2,-1 --------------------------------------------UACUAGACUGAAGCUCCUUGAGu----------------------- 205 -2,-1 --------------------------------------------UACUAGACUGAAGCUCCUUGAGuu---------------------- 2 -2,-1 --------------------------------------------UACUAGACUGAAGCUCCUUGAGG----------------------- 1004 -2,0 --------------------------------------------UACUAGACUGAAGCUCCUUGAGGc---------------------- 2 -2,0 --------------------------------------------UACUAGACUGAAGCUCCUUGAGGu---------------------- 106 -2,0 --------------------------------------------UACUAGACUGAAGCUCCUUGAGGuu--------------------- 2 -2,0 --------------------------------------------UACUAGACUGAAGCUCCUUGAGGA---------------------- 28 -2,1 --------------------------------------------UACUAGACUGAAGCUCCUUGAGGAu--------------------- 2 -2,1 ---------------------------------------------ACUAGACUGAAGCUCCUUG-------------------------- 2 -1,-3 ---------------------------------------------ACUAGACUGAAGCUCCUUGA------------------------- 69 -1,-2 ---------------------------------------------ACUAGACUGAAGCUCCUUGAa------------------------ 3 -1,-2 ---------------------------------------------ACUAGACUGAAGCUCCUUGAG------------------------ 338 -1,-1 ---------------------------------------------ACUAGACUGAAGCUCCUUGAGa----------------------- 81 -1,-1 ---------------------------------------------ACUAGACUGAAGCUCCUUGAGu----------------------- 50 -1,-1 ---------------------------------------------ACUAGACUGAAGCUCCUUGAGG----------------------- 628 -1,0 ---------------------------------------------ACUAGACUGAAGCUCCUUGAGGu---------------------- 50 -1,0 ---------------------------------------------ACUAGACUGAAGCUCCUUGAGGuu--------------------- 2 -1,0 ---------------------------------------------ACUAGACUGAAGCUCCUUGAGGA---------------------- 84 -1,1 ---------------------------------------------ACUAGACUGAAGCUCCUUGAGGAa--------------------- 2 -1,1 ----------------------------------------------CUAGACUGAAGCUCCUUG-------------------------- 282 0,-3 ----------------------------------------------CUAGACUGAAGCUCCUUGc------------------------- 2 0,-3 ----------------------------------------------CUAGACUGAAGCUCCUUGu------------------------- 37 0,-3 ----------------------------------------------CUAGACUGAAGCUCCUUGuu------------------------ 2 0,-3 ----------------------------------------------CUAGACUGAAGCUCCUUGA------------------------- 1538 0,-2 ----------------------------------------------CUAGACUGAAGCUCCUUGAa------------------------ 251 0,-2 ----------------------------------------------CUAGACUGAAGCUCCUUGAaa----------------------- 176 0,-2 ----------------------------------------------CUAGACUGAAGCUCCUUGAau----------------------- 32 0,-2 ----------------------------------------------CUAGACUGAAGCUCCUUGAu------------------------ 159 0,-2 ----------------------------------------------CUAGACUGAAGCUCCUUGAuu----------------------- 28 0,-2 ----------------------------------------------CUAGACUGAAGCUCCUUGAG------------------------ 9370 0,-1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGa----------------------- 2787 0,-1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGaa---------------------- 380 0,-1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGau---------------------- 82 0,-1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGc----------------------- 12 0,-1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGu----------------------- 2612 0,-1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGuu---------------------- 106 0,-1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGG----------------------- 18528 0,0 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGc---------------------- 47 0,0 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGg---------------------- 16 0,0 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGu---------------------- 3918 0,0 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGuu--------------------- 671 0,0 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGA---------------------- 8535 0,1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGAa--------------------- 4345 0,1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGAaa-------------------- 658 0,1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGAau-------------------- 588 0,1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGAg--------------------- 170 0,1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGAu--------------------- 1547 0,1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGAuu-------------------- 166 0,1 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGAC--------------------- 36 0,2 ----------------------------------------------CUAGACUGAAGCUCCUUGAGGACu-------------------- 6 0,2 -----------------------------------------------UAGACUGAAGCUCCUUGA------------------------- 23 1,-2 -----------------------------------------------UAGACUGAAGCUCCUUGAa------------------------ 7 1,-2 -----------------------------------------------UAGACUGAAGCUCCUUGAG------------------------ 172 1,-1 -----------------------------------------------UAGACUGAAGCUCCUUGAGa----------------------- 43 1,-1 -----------------------------------------------UAGACUGAAGCUCCUUGAGaa---------------------- 3 1,-1 -----------------------------------------------UAGACUGAAGCUCCUUGAGau---------------------- 2 1,-1 -----------------------------------------------UAGACUGAAGCUCCUUGAGu----------------------- 51 1,-1 -----------------------------------------------UAGACUGAAGCUCCUUGAGuu---------------------- 2 1,-1 -----------------------------------------------UAGACUGAAGCUCCUUGAGG----------------------- 379 1,0 -----------------------------------------------UAGACUGAAGCUCCUUGAGGu---------------------- 79 1,0 -----------------------------------------------UAGACUGAAGCUCCUUGAGGuu--------------------- 10 1,0 -----------------------------------------------UAGACUGAAGCUCCUUGAGGA---------------------- 189 1,1 -----------------------------------------------UAGACUGAAGCUCCUUGAGGAa--------------------- 84 1,1 -----------------------------------------------UAGACUGAAGCUCCUUGAGGAaa-------------------- 9 1,1 -----------------------------------------------UAGACUGAAGCUCCUUGAGGAau-------------------- 9 1,1 -----------------------------------------------UAGACUGAAGCUCCUUGAGGAg--------------------- 2 1,1 -----------------------------------------------UAGACUGAAGCUCCUUGAGGAu--------------------- 17 1,1 -----------------------------------------------UAGACUGAAGCUCCUUGAGGAuu-------------------- 5 1,1 ------------------------------------------------AGACUGAAGCUCCUUGAG------------------------ 2 2,-1 ------------------------------------------------AGACUGAAGCUCCUUGAGG----------------------- 2 2,0 ------------------------------------------------AGACUGAAGCUCCUUGAGGA---------------------- 4 2,1 ------------------------------------------------AGACUGAAGCUCCUUGAGGAuu-------------------- 12 2,1 ------------------------------------------------AGACUGAAGCUCCUUGAGGAC--------------------- 2 2,2 ------------------------------------------------AGACUGAAGCUCCUUGAGGACu-------------------- 5 2,2 >hsa-mir-151b 3pM:60-77 Tumor accucugaugugucagucucucuucagggcucccgagacacagaaacagacaccugcccUCGAGGAGCUCACAGUCUagacaaacaaacccagggu ----------------------------------------------------------CUCGAGGAGCUCACAGUCU------------------- 6 -1,0 ----------------------------------------------------------CUCGAGGAGCUCACAGUCUAu----------------- 2 -1,1 ----------------------------------------------------------CUCGAGGAGCUCACAGUCUAG----------------- 102 -1,2 ----------------------------------------------------------CUCGAGGAGCUCACAGUCUAGc---------------- 2 -1,2 -----------------------------------------------------------UCGAGGAGCUCACAGUCU------------------- 252 0,0 -----------------------------------------------------------UCGAGGAGCUCACAGUCUu------------------ 10 0,0 -----------------------------------------------------------UCGAGGAGCUCACAGUCUA------------------ 101 0,1 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAa----------------- 24 0,1 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAau---------------- 21 0,1 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAu----------------- 13 0,1 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAuu---------------- 22 0,1 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAG----------------- 2299 0,2 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAGc---------------- 16 0,2 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAGg---------------- 16 0,2 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAGA---------------- 98 0,3 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAGAa--------------- 8 0,3 -----------------------------------------------------------UCGAGGAGCUCACAGUCUAGAaa-------------- 2 0,3 ------------------------------------------------------------CGAGGAGCUCACAGUCUAG----------------- 28 1,2 ------------------------------------------------------------CGAGGAGCUCACAGUCUAGAa--------------- 2 1,3 -------------------------------------------------------------GAGGAGCUCACAGUCUAG----------------- 11 2,2 >hsa-mir-152 3pM:54-74 Tumor ugucccccccggcccagguucugugauacacuccgacucgggcucuggagcagUCAGUGCAUGACAGAACUUGGgcccggaaggacc ---------------AGGUUCUGUGAUACACUCCGACU------------------------------------------------- 16 ----------------------------------------------------GUCAGUGCAUGACAGAACUUG-------------- 2 -1,-1 ----------------------------------------------------GUCAGUGCAUGACAGAACUUGu------------- 2 -1,-1 ----------------------------------------------------GUCAGUGCAUGACAGAACUUGG------------- 73 -1,0 ----------------------------------------------------GUCAGUGCAUGACAGAACUUGGa------------ 2 -1,0 -----------------------------------------------------UCAGUGCAUGACAGAACU---------------- 27 0,-3 -----------------------------------------------------UCAGUGCAUGACAGAACUU--------------- 207 0,-2 -----------------------------------------------------UCAGUGCAUGACAGAACUUa-------------- 4 0,-2 -----------------------------------------------------UCAGUGCAUGACAGAACUUu-------------- 2 0,-2 -----------------------------------------------------UCAGUGCAUGACAGAACUUuu------------- 2 0,-2 -----------------------------------------------------UCAGUGCAUGACAGAACUUG-------------- 1535 0,-1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGa------------- 114 0,-1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGaa------------ 2 0,-1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGu------------- 427 0,-1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGuu------------ 10 0,-1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGG------------- 14124 0,0 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGa------------ 1473 0,0 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGaa----------- 202 0,0 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGau----------- 21 0,0 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGc------------ 10 0,0 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGu------------ 3452 0,0 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGuu----------- 262 0,0 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGG------------ 3161 0,1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGGa----------- 2085 0,1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGGaa---------- 148 0,1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGGau---------- 91 0,1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGGu----------- 3947 0,1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGGuu---------- 200 0,1 -----------------------------------------------------UCAGUGCAUGACAGAACUUGGGC----------- 8 0,2 ------------------------------------------------------CAGUGCAUGACAGAACUUGG------------- 64 1,0 ------------------------------------------------------CAGUGCAUGACAGAACUUGGa------------ 2 1,0 ------------------------------------------------------CAGUGCAUGACAGAACUUGGu------------ 9 1,0 ------------------------------------------------------CAGUGCAUGACAGAACUUGGG------------ 5 1,1 ------------------------------------------------------CAGUGCAUGACAGAACUUGGGu----------- 23 1,1 -------------------------------------------------------AGUGCAUGACAGAACUUG-------------- 2 2,-1 -------------------------------------------------------AGUGCAUGACAGAACUUGu------------- 2 2,-1 -------------------------------------------------------AGUGCAUGACAGAACUUGG------------- 93 2,0 -------------------------------------------------------AGUGCAUGACAGAACUUGGa------------ 2 2,0 -------------------------------------------------------AGUGCAUGACAGAACUUGGu------------ 21 2,0 -------------------------------------------------------AGUGCAUGACAGAACUUGGG------------ 9 2,1 -------------------------------------------------------AGUGCAUGACAGAACUUGGGa----------- 3 2,1 -------------------------------------------------------AGUGCAUGACAGAACUUGGGu----------- 22 2,1 >hsa-mir-153-1 3pM:54-75 Tumor cucacagcugccagugucauuuuugugaucugcagcuaguauucucacuccagUUGCAUAGUCACAAAAGUGAUCauuggcagguguggc ---------------GUCAUUUUUGUGAUCUGCAGCU----------------------------------------------------- 6 -----------------------------------------------------UUGCAUAGUCACAAAAGUG------------------ 2 0,-3 -----------------------------------------------------UUGCAUAGUCACAAAAGUGA----------------- 62 0,-2 -----------------------------------------------------UUGCAUAGUCACAAAAGUGAa---------------- 2 0,-2 -----------------------------------------------------UUGCAUAGUCACAAAAGUGAU---------------- 318 0,-1 -----------------------------------------------------UUGCAUAGUCACAAAAGUGAUa--------------- 22 0,-1 -----------------------------------------------------UUGCAUAGUCACAAAAGUGAUC--------------- 372 0,0 -----------------------------------------------------UUGCAUAGUCACAAAAGUGAUCA-------------- 129 0,1 -----------------------------------------------------UUGCAUAGUCACAAAAGUGAUCAU------------- 102 0,2 -----------------------------------------------------UUGCAUAGUCACAAAAGUGAUCAUU------------ 2 0,3 ------------------------------------------------------UGCAUAGUCACAAAAGUGAU---------------- 8 1,-1 ------------------------------------------------------UGCAUAGUCACAAAAGUGAUC--------------- 8 1,0 ------------------------------------------------------UGCAUAGUCACAAAAGUGAUCAU------------- 2 1,2 >hsa-mir-153-2 3pM:53-74 Tumor agcgguggccagugucauuuuugugauguugcagcuaguaauaugagcccagUUGCAUAGUCACAAAAGUGAUCauuggaaacugug -------------GUCAUUUUUGUGAUGUUGCAG----------------------------------------------------- 3 -------------GUCAUUUUUGUGAUGUUGCAGCU--------------------------------------------------- 13 ----------------------------------------------------UUGCAUAGUCACAAAAGUG---------------- 2 0,-3 ----------------------------------------------------UUGCAUAGUCACAAAAGUGA--------------- 62 0,-2 ----------------------------------------------------UUGCAUAGUCACAAAAGUGAa-------------- 2 0,-2 ----------------------------------------------------UUGCAUAGUCACAAAAGUGAU-------------- 318 0,-1 ----------------------------------------------------UUGCAUAGUCACAAAAGUGAUa------------- 22 0,-1 ----------------------------------------------------UUGCAUAGUCACAAAAGUGAUC------------- 372 0,0 ----------------------------------------------------UUGCAUAGUCACAAAAGUGAUCA------------ 129 0,1 ----------------------------------------------------UUGCAUAGUCACAAAAGUGAUCAU----------- 102 0,2 ----------------------------------------------------UUGCAUAGUCACAAAAGUGAUCAUU---------- 2 0,3 -----------------------------------------------------UGCAUAGUCACAAAAGUGAU-------------- 8 1,-1 -----------------------------------------------------UGCAUAGUCACAAAAGUGAUC------------- 8 1,0 -----------------------------------------------------UGCAUAGUCACAAAAGUGAUCAU----------- 2 1,2 >hsa-mir-1537 3pM:40-61 Tumor acagcuguaauuagucaguuuucuguccuguccacacagAAAACCGUCUAGUUACAGUUGU --AGCUGUAAUUAGUCAGUUUUCU------------------------------------- 2 --------------------------------------GAAAACCGUCUAGUUACAGUUG- 3 -1,-1 ---------------------------------------AAAACCGUCUAGUUACAGUU-- 5 0,-2 ---------------------------------------AAAACCGUCUAGUUACAGUUGU 11 0,0 >hsa-mir-154 MA:15-36;mi:51-72 Tumor gugguacuugaagaUAGGUUAUCCGUGUUGCCUUCGcuuuauuugugacgAAUCAUACACGGUUGACCUAUUuuucaguaccaa --------------UAGGUUAUCCGUGUUGCCUUC------------------------------------------------- 12 0,-1 --------------UAGGUUAUCCGUGUUGCCUUCG------------------------------------------------ 200 0,0 --------------UAGGUUAUCCGUGUUGCCUUCGa----------------------------------------------- 8 0,0 --------------UAGGUUAUCCGUGUUGCCUUCGu----------------------------------------------- 2 0,0 ---------------AGGUUAUCCGUGUUGCCUUCG------------------------------------------------ 17 1,0 --------------------------------------------------AAUCAUACACGGUUGACCUAU------------- 45 0,-1 --------------------------------------------------AAUCAUACACGGUUGACCUAUU------------ 241 0,0 --------------------------------------------------AAUCAUACACGGUUGACCUAUUU----------- 4 0,1 >hsa-mir-155 MA:4-26;mi:43-64 Tumor cugUUAAUGCUAAUCGUGAUAGGGGUuuuugccuccaacugaCUCCUACAUAUUAGCAUUAACAg ---UUAAUGCUAAUCGUGAUA-------------------------------------------- 25 0,-5 ---UUAAUGCUAAUCGUGAUAG------------------------------------------- 158 0,-4 ---UUAAUGCUAAUCGUGAUAGa------------------------------------------ 33 0,-4 ---UUAAUGCUAAUCGUGAUAGu------------------------------------------ 7 0,-4 ---UUAAUGCUAAUCGUGAUAGG------------------------------------------ 1768 0,-3 ---UUAAUGCUAAUCGUGAUAGGa----------------------------------------- 298 0,-3 ---UUAAUGCUAAUCGUGAUAGGaa---------------------------------------- 35 0,-3 ---UUAAUGCUAAUCGUGAUAGGau---------------------------------------- 2 0,-3 ---UUAAUGCUAAUCGUGAUAGGu----------------------------------------- 59 0,-3 ---UUAAUGCUAAUCGUGAUAGGG----------------------------------------- 2260 0,-2 ---UUAAUGCUAAUCGUGAUAGGGa---------------------------------------- 1176 0,-2 ---UUAAUGCUAAUCGUGAUAGGGaa--------------------------------------- 205 0,-2 ---UUAAUGCUAAUCGUGAUAGGGau--------------------------------------- 118 0,-2 ---UUAAUGCUAAUCGUGAUAGGGc---------------------------------------- 2 0,-2 ---UUAAUGCUAAUCGUGAUAGGGu---------------------------------------- 262 0,-2 ---UUAAUGCUAAUCGUGAUAGGGuu--------------------------------------- 10 0,-2 ---UUAAUGCUAAUCGUGAUAGGGG---------------------------------------- 1850 0,-1 ---UUAAUGCUAAUCGUGAUAGGGGa--------------------------------------- 771 0,-1 ---UUAAUGCUAAUCGUGAUAGGGGaa-------------------------------------- 75 0,-1 ---UUAAUGCUAAUCGUGAUAGGGGau-------------------------------------- 85 0,-1 ---UUAAUGCUAAUCGUGAUAGGGGc--------------------------------------- 9 0,-1 ---UUAAUGCUAAUCGUGAUAGGGGg--------------------------------------- 8 0,-1 ---UUAAUGCUAAUCGUGAUAGGGGU--------------------------------------- 6916 0,0 ---UUAAUGCUAAUCGUGAUAGGGGUa-------------------------------------- 261 0,0 ---UUAAUGCUAAUCGUGAUAGGGGUaa------------------------------------- 79 0,0 ---UUAAUGCUAAUCGUGAUAGGGGUau------------------------------------- 143 0,0 ---UUAAUGCUAAUCGUGAUAGGGGUc-------------------------------------- 2 0,0 ---UUAAUGCUAAUCGUGAUAGGGGUg-------------------------------------- 3 0,0 ---UUAAUGCUAAUCGUGAUAGGGGUU-------------------------------------- 3923 0,1 ---UUAAUGCUAAUCGUGAUAGGGGUUa------------------------------------- 181 0,1 ---UUAAUGCUAAUCGUGAUAGGGGUUg------------------------------------- 4 0,1 ---UUAAUGCUAAUCGUGAUAGGGGUUU------------------------------------- 698 0,2 ----UAAUGCUAAUCGUGAUAGG------------------------------------------ 21 1,-3 ----UAAUGCUAAUCGUGAUAGGa----------------------------------------- 4 1,-3 ----UAAUGCUAAUCGUGAUAGGG----------------------------------------- 63 1,-2 ----UAAUGCUAAUCGUGAUAGGGa---------------------------------------- 13 1,-2 ----UAAUGCUAAUCGUGAUAGGGaa--------------------------------------- 2 1,-2 ----UAAUGCUAAUCGUGAUAGGGu---------------------------------------- 9 1,-2 ----UAAUGCUAAUCGUGAUAGGGG---------------------------------------- 47 1,-1 ----UAAUGCUAAUCGUGAUAGGGGa--------------------------------------- 10 1,-1 ----UAAUGCUAAUCGUGAUAGGGGau-------------------------------------- 2 1,-1 ----UAAUGCUAAUCGUGAUAGGGGU--------------------------------------- 177 1,0 ----UAAUGCUAAUCGUGAUAGGGGUa-------------------------------------- 5 1,0 ----UAAUGCUAAUCGUGAUAGGGGUaa------------------------------------- 2 1,0 ----UAAUGCUAAUCGUGAUAGGGGUau------------------------------------- 2 1,0 ----UAAUGCUAAUCGUGAUAGGGGUU-------------------------------------- 122 1,1 ----UAAUGCUAAUCGUGAUAGGGGUUU------------------------------------- 5 1,2 -----AAUGCUAAUCGUGAUAGGGG---------------------------------------- 2 2,-1 -----AAUGCUAAUCGUGAUAGGGGUU-------------------------------------- 2 2,1 ------------------------------------------CUCCUACAUAUUAGCAUUAAC-- 4 0,-1 ------------------------------------------CUCCUACAUAUUAGCAUUAACA- 15 0,0 >hsa-mir-15a MA:14-35;mi:51-72 Tumor ccuuggaguaaagUAGCAGCACAUAAUGGUUUGUGgauuuugaaaaggugCAGGCCAUAUUGUGCUGCCUCAaaaauacaagg -----------AGUAGCAGCACAUAAUGGUUUGU------------------------------------------------- 2 -2,-1 -------------UAGCAGCACAUAAUGGUU---------------------------------------------------- 118 0,-4 -------------UAGCAGCACAUAAUGGUUa--------------------------------------------------- 7 0,-4 -------------UAGCAGCACAUAAUGGUUU--------------------------------------------------- 384 0,-3 -------------UAGCAGCACAUAAUGGUUUa-------------------------------------------------- 15 0,-3 -------------UAGCAGCACAUAAUGGUUUau------------------------------------------------- 30 0,-3 -------------UAGCAGCACAUAAUGGUUUu-------------------------------------------------- 12 0,-3 -------------UAGCAGCACAUAAUGGUUUuu------------------------------------------------- 75 0,-3 -------------UAGCAGCACAUAAUGGUUUG-------------------------------------------------- 2805 0,-2 -------------UAGCAGCACAUAAUGGUUUGa------------------------------------------------- 422 0,-2 -------------UAGCAGCACAUAAUGGUUUGaa------------------------------------------------ 8 0,-2 -------------UAGCAGCACAUAAUGGUUUGc------------------------------------------------- 15 0,-2 -------------UAGCAGCACAUAAUGGUUUGg------------------------------------------------- 25 0,-2 -------------UAGCAGCACAUAAUGGUUUGU------------------------------------------------- 21599 0,-1 -------------UAGCAGCACAUAAUGGUUUGUa------------------------------------------------ 260 0,-1 -------------UAGCAGCACAUAAUGGUUUGUaa----------------------------------------------- 148 0,-1 -------------UAGCAGCACAUAAUGGUUUGUau----------------------------------------------- 16 0,-1 -------------UAGCAGCACAUAAUGGUUUGUu------------------------------------------------ 126 0,-1 -------------UAGCAGCACAUAAUGGUUUGUuu----------------------------------------------- 20 0,-1 -------------UAGCAGCACAUAAUGGUUUGUG------------------------------------------------ 8801 0,0 -------------UAGCAGCACAUAAUGGUUUGUGa----------------------------------------------- 5923 0,0 -------------UAGCAGCACAUAAUGGUUUGUGaa---------------------------------------------- 50 0,0 -------------UAGCAGCACAUAAUGGUUUGUGau---------------------------------------------- 9 0,0 -------------UAGCAGCACAUAAUGGUUUGUGc----------------------------------------------- 37 0,0 -------------UAGCAGCACAUAAUGGUUUGUGu----------------------------------------------- 6789 0,0 -------------UAGCAGCACAUAAUGGUUUGUGuu---------------------------------------------- 99 0,0 -------------UAGCAGCACAUAAUGGUUUGUGG----------------------------------------------- 1044 0,1 -------------UAGCAGCACAUAAUGGUUUGUGGu---------------------------------------------- 80 0,1 -------------UAGCAGCACAUAAUGGUUUGUGGA---------------------------------------------- 2060 0,2 -------------UAGCAGCACAUAAUGGUUUGUGGAa--------------------------------------------- 166 0,2 -------------UAGCAGCACAUAAUGGUUUGUGGAU--------------------------------------------- 51 0,3 --------------AGCAGCACAUAAUGGUUU--------------------------------------------------- 4 1,-3 --------------AGCAGCACAUAAUGGUUUG-------------------------------------------------- 42 1,-2 --------------AGCAGCACAUAAUGGUUUGc------------------------------------------------- 2 1,-2 --------------AGCAGCACAUAAUGGUUUGU------------------------------------------------- 728 1,-1 --------------AGCAGCACAUAAUGGUUUGUaa----------------------------------------------- 2 1,-1 --------------AGCAGCACAUAAUGGUUUGUG------------------------------------------------ 270 1,0 --------------AGCAGCACAUAAUGGUUUGUGa----------------------------------------------- 160 1,0 --------------AGCAGCACAUAAUGGUUUGUGc----------------------------------------------- 3 1,0 --------------AGCAGCACAUAAUGGUUUGUGu----------------------------------------------- 299 1,0 --------------AGCAGCACAUAAUGGUUUGUGG----------------------------------------------- 24 1,1 --------------AGCAGCACAUAAUGGUUUGUGGA---------------------------------------------- 54 1,2 ---------------GCAGCACAUAAUGGUUUGU------------------------------------------------- 18 2,-1 ---------------GCAGCACAUAAUGGUUUGUG------------------------------------------------ 5 2,0 ---------------GCAGCACAUAAUGGUUUGUGa----------------------------------------------- 2 2,0 ---------------GCAGCACAUAAUGGUUUGUGu----------------------------------------------- 4 2,0 --------------------------------------------------CAGGCCAUAUUGUGCUGCC-------------- 4 0,-3 --------------------------------------------------CAGGCCAUAUUGUGCUGCCU------------- 15 0,-2 --------------------------------------------------CAGGCCAUAUUGUGCUGCCUCu----------- 4 0,-1 --------------------------------------------------CAGGCCAUAUUGUGCUGCCUCA----------- 47 0,0 --------------------------------------------------CAGGCCAUAUUGUGCUGCCUCAuu--------- 2 0,0 --------------------------------------------------CAGGCCAUAUUGUGCUGCCUCAAA--------- 2 0,2 >hsa-mir-15b MA:20-41;mi:58-79 Tumor uugaggccuuaaaguacugUAGCAGCACAUCAUGGUUUACAugcuacagucaagaugCGAAUCAUUAUUUGCUGCUCUAgaaauuuaaggaaauucau -------------------UAGCAGCACAUCAUGGUU------------------------------------------------------------- 446 0,-4 -------------------UAGCAGCACAUCAUGGUUa------------------------------------------------------------ 33 0,-4 -------------------UAGCAGCACAUCAUGGUUaa----------------------------------------------------------- 5 0,-4 -------------------UAGCAGCACAUCAUGGUUg------------------------------------------------------------ 2 0,-4 -------------------UAGCAGCACAUCAUGGUUU------------------------------------------------------------ 1942 0,-3 -------------------UAGCAGCACAUCAUGGUUUu----------------------------------------------------------- 55 0,-3 -------------------UAGCAGCACAUCAUGGUUUA----------------------------------------------------------- 2331 0,-2 -------------------UAGCAGCACAUCAUGGUUUAa---------------------------------------------------------- 472 0,-2 -------------------UAGCAGCACAUCAUGGUUUAaa--------------------------------------------------------- 79 0,-2 -------------------UAGCAGCACAUCAUGGUUUAg---------------------------------------------------------- 6 0,-2 -------------------UAGCAGCACAUCAUGGUUUAu---------------------------------------------------------- 116 0,-2 -------------------UAGCAGCACAUCAUGGUUUAC---------------------------------------------------------- 9446 0,-1 -------------------UAGCAGCACAUCAUGGUUUACc--------------------------------------------------------- 97 0,-1 -------------------UAGCAGCACAUCAUGGUUUACg--------------------------------------------------------- 10 0,-1 -------------------UAGCAGCACAUCAUGGUUUACu--------------------------------------------------------- 42 0,-1 -------------------UAGCAGCACAUCAUGGUUUACA--------------------------------------------------------- 17209 0,0 -------------------UAGCAGCACAUCAUGGUUUACAa-------------------------------------------------------- 317 0,0 -------------------UAGCAGCACAUCAUGGUUUACAaa------------------------------------------------------- 2 0,0 -------------------UAGCAGCACAUCAUGGUUUACAg-------------------------------------------------------- 2 0,0 -------------------UAGCAGCACAUCAUGGUUUACAU-------------------------------------------------------- 64 0,1 --------------------AGCAGCACAUCAUGGUUU------------------------------------------------------------ 37 1,-3 --------------------AGCAGCACAUCAUGGUUUA----------------------------------------------------------- 41 1,-2 --------------------AGCAGCACAUCAUGGUUUAa---------------------------------------------------------- 2 1,-2 --------------------AGCAGCACAUCAUGGUUUAu---------------------------------------------------------- 2 1,-2 --------------------AGCAGCACAUCAUGGUUUAC---------------------------------------------------------- 247 1,-1 --------------------AGCAGCACAUCAUGGUUUACA--------------------------------------------------------- 448 1,0 --------------------AGCAGCACAUCAUGGUUUACAa-------------------------------------------------------- 4 1,0 ---------------------GCAGCACAUCAUGGUUUAC---------------------------------------------------------- 6 2,-1 ---------------------GCAGCACAUCAUGGUUUACA--------------------------------------------------------- 12 2,0 ---------------------------------------------------------CGAAUCAUUAUUUGCUGCU---------------------- 156 0,-3 ---------------------------------------------------------CGAAUCAUUAUUUGCUGCUau-------------------- 2 0,-3 ---------------------------------------------------------CGAAUCAUUAUUUGCUGCUu--------------------- 4 0,-3 ---------------------------------------------------------CGAAUCAUUAUUUGCUGCUC--------------------- 82 0,-2 ---------------------------------------------------------CGAAUCAUUAUUUGCUGCUCU-------------------- 910 0,-1 ---------------------------------------------------------CGAAUCAUUAUUUGCUGCUCUu------------------- 56 0,-1 ---------------------------------------------------------CGAAUCAUUAUUUGCUGCUCUuu------------------ 13 0,-1 ---------------------------------------------------------CGAAUCAUUAUUUGCUGCUCUA------------------- 388 0,0 ---------------------------------------------------------CGAAUCAUUAUUUGCUGCUCUAa------------------ 76 0,0 ---------------------------------------------------------CGAAUCAUUAUUUGCUGCUCUAu------------------ 184 0,0 ----------------------------------------------------------GAAUCAUUAUUUGCUGCU---------------------- 4 1,-3 ----------------------------------------------------------GAAUCAUUAUUUGCUGCUCU-------------------- 35 1,-1 ----------------------------------------------------------GAAUCAUUAUUUGCUGCUCUuu------------------ 2 1,-1 ----------------------------------------------------------GAAUCAUUAUUUGCUGCUCUA------------------- 6 1,0 ----------------------------------------------------------GAAUCAUUAUUUGCUGCUCUAu------------------ 2 1,0 >hsa-mir-16-1 MA:14-35;mi:56-77 Tumor gucagcagugccuUAGCAGCACGUAAAUAUUGGCGuuaagauucuaaaauuaucuCCAGUAUUAACUGUGCUGCUGAaguaagguugac ------------UUAGCAGCACGUAAAUAUUGGCG------------------------------------------------------ 4 -1,0 -------------UAGCAGCACGUAAAUAUU---------------------------------------------------------- 877 0,-4 -------------UAGCAGCACGUAAAUAUUa--------------------------------------------------------- 10 0,-4 -------------UAGCAGCACGUAAAUAUUG--------------------------------------------------------- 1698 0,-3 -------------UAGCAGCACGUAAAUAUUGa-------------------------------------------------------- 247 0,-3 -------------UAGCAGCACGUAAAUAUUGaa------------------------------------------------------- 13 0,-3 -------------UAGCAGCACGUAAAUAUUGu-------------------------------------------------------- 27 0,-3 -------------UAGCAGCACGUAAAUAUUGG-------------------------------------------------------- 8337 0,-2 -------------UAGCAGCACGUAAAUAUUGGa------------------------------------------------------- 1312 0,-2 -------------UAGCAGCACGUAAAUAUUGGaa------------------------------------------------------ 302 0,-2 -------------UAGCAGCACGUAAAUAUUGGau------------------------------------------------------ 6 0,-2 -------------UAGCAGCACGUAAAUAUUGGg------------------------------------------------------- 12 0,-2 -------------UAGCAGCACGUAAAUAUUGGu------------------------------------------------------- 119 0,-2 -------------UAGCAGCACGUAAAUAUUGGC------------------------------------------------------- 12393 0,-1 -------------UAGCAGCACGUAAAUAUUGGCa------------------------------------------------------ 2795 0,-1 -------------UAGCAGCACGUAAAUAUUGGCaa----------------------------------------------------- 483 0,-1 -------------UAGCAGCACGUAAAUAUUGGCau----------------------------------------------------- 143 0,-1 -------------UAGCAGCACGUAAAUAUUGGCc------------------------------------------------------ 48 0,-1 -------------UAGCAGCACGUAAAUAUUGGCu------------------------------------------------------ 396 0,-1 -------------UAGCAGCACGUAAAUAUUGGCuu----------------------------------------------------- 22 0,-1 -------------UAGCAGCACGUAAAUAUUGGCG------------------------------------------------------ 108232 0,0 -------------UAGCAGCACGUAAAUAUUGGCGa----------------------------------------------------- 9102 0,0 -------------UAGCAGCACGUAAAUAUUGGCGaa---------------------------------------------------- 250 0,0 -------------UAGCAGCACGUAAAUAUUGGCGau---------------------------------------------------- 201 0,0 -------------UAGCAGCACGUAAAUAUUGGCGc----------------------------------------------------- 68 0,0 -------------UAGCAGCACGUAAAUAUUGGCGg----------------------------------------------------- 23 0,0 -------------UAGCAGCACGUAAAUAUUGGCGU----------------------------------------------------- 19522 0,1 -------------UAGCAGCACGUAAAUAUUGGCGUU---------------------------------------------------- 1298 0,2 -------------UAGCAGCACGUAAAUAUUGGCGUUu--------------------------------------------------- 289 0,2 -------------UAGCAGCACGUAAAUAUUGGCGUUA--------------------------------------------------- 19 0,3 --------------AGCAGCACGUAAAUAUUG--------------------------------------------------------- 27 1,-3 --------------AGCAGCACGUAAAUAUUGG-------------------------------------------------------- 253 1,-2 --------------AGCAGCACGUAAAUAUUGGa------------------------------------------------------- 21 1,-2 --------------AGCAGCACGUAAAUAUUGGaa------------------------------------------------------ 2 1,-2 --------------AGCAGCACGUAAAUAUUGGC------------------------------------------------------- 486 1,-1 --------------AGCAGCACGUAAAUAUUGGCa------------------------------------------------------ 79 1,-1 --------------AGCAGCACGUAAAUAUUGGCaa----------------------------------------------------- 8 1,-1 --------------AGCAGCACGUAAAUAUUGGCc------------------------------------------------------ 2 1,-1 --------------AGCAGCACGUAAAUAUUGGCu------------------------------------------------------ 2 1,-1 --------------AGCAGCACGUAAAUAUUGGCG------------------------------------------------------ 4643 1,0 --------------AGCAGCACGUAAAUAUUGGCGa----------------------------------------------------- 280 1,0 --------------AGCAGCACGUAAAUAUUGGCGaa---------------------------------------------------- 2 1,0 --------------AGCAGCACGUAAAUAUUGGCGau---------------------------------------------------- 2 1,0 --------------AGCAGCACGUAAAUAUUGGCGc----------------------------------------------------- 2 1,0 --------------AGCAGCACGUAAAUAUUGGCGU----------------------------------------------------- 765 1,1 --------------AGCAGCACGUAAAUAUUGGCGUU---------------------------------------------------- 19 1,2 --------------AGCAGCACGUAAAUAUUGGCGUUu--------------------------------------------------- 2 1,2 ---------------GCAGCACGUAAAUAUUGG-------------------------------------------------------- 12 2,-2 ---------------GCAGCACGUAAAUAUUGGC------------------------------------------------------- 9 2,-1 ---------------GCAGCACGUAAAUAUUGGCG------------------------------------------------------ 350 2,0 ---------------GCAGCACGUAAAUAUUGGCGa----------------------------------------------------- 9 2,0 ---------------GCAGCACGUAAAUAUUGGCGU----------------------------------------------------- 35 2,1 -------------------------------------------------------CCAGUAUUAACUGUGCUGCU-------------- 2 0,-2 -------------------------------------------------------CCAGUAUUAACUGUGCUGCUG------------- 6 0,-1 -------------------------------------------------------CCAGUAUUAACUGUGCUGCUGu------------ 4 0,-1 -------------------------------------------------------CCAGUAUUAACUGUGCUGCUGA------------ 697 0,0 -------------------------------------------------------CCAGUAUUAACUGUGCUGCUGAu----------- 19 0,0 -------------------------------------------------------CCAGUAUUAACUGUGCUGCUGAA----------- 467 0,1 -------------------------------------------------------CCAGUAUUAACUGUGCUGCUGAAa---------- 17 0,1 -------------------------------------------------------CCAGUAUUAACUGUGCUGCUGAAu---------- 4 0,1 --------------------------------------------------------CAGUAUUAACUGUGCUGCUGA------------ 7 1,0 --------------------------------------------------------CAGUAUUAACUGUGCUGCUGAA----------- 4 1,1 >hsa-mir-16-2 MA:10-31;mi:53-74 Tumor guuccacucUAGCAGCACGUAAAUAUUGGCGuagugaaauauauauuaaacaCCAAUAUUACUGUGCUGCUUUAgugugac -------UCUAGCAGCACGUAAAUAUUGGCG-------------------------------------------------- 10 -2,0 --------CUAGCAGCACGUAAAUAUUGG---------------------------------------------------- 14 -1,-2 --------CUAGCAGCACGUAAAUAUUGGC--------------------------------------------------- 29 -1,-1 --------CUAGCAGCACGUAAAUAUUGGCG-------------------------------------------------- 508 -1,0 --------CUAGCAGCACGUAAAUAUUGGCGa------------------------------------------------- 8 -1,0 --------CUAGCAGCACGUAAAUAUUGGCGU------------------------------------------------- 62 -1,1 --------CUAGCAGCACGUAAAUAUUGGCGUu------------------------------------------------ 2 -1,1 ---------UAGCAGCACGUAAAUAUU------------------------------------------------------ 877 0,-4 ---------UAGCAGCACGUAAAUAUUa----------------------------------------------------- 10 0,-4 ---------UAGCAGCACGUAAAUAUUG----------------------------------------------------- 1698 0,-3 ---------UAGCAGCACGUAAAUAUUGa---------------------------------------------------- 247 0,-3 ---------UAGCAGCACGUAAAUAUUGaa--------------------------------------------------- 13 0,-3 ---------UAGCAGCACGUAAAUAUUGu---------------------------------------------------- 27 0,-3 ---------UAGCAGCACGUAAAUAUUGG---------------------------------------------------- 8337 0,-2 ---------UAGCAGCACGUAAAUAUUGGa--------------------------------------------------- 1312 0,-2 ---------UAGCAGCACGUAAAUAUUGGaa-------------------------------------------------- 302 0,-2 ---------UAGCAGCACGUAAAUAUUGGau-------------------------------------------------- 6 0,-2 ---------UAGCAGCACGUAAAUAUUGGg--------------------------------------------------- 12 0,-2 ---------UAGCAGCACGUAAAUAUUGGu--------------------------------------------------- 119 0,-2 ---------UAGCAGCACGUAAAUAUUGGC--------------------------------------------------- 12393 0,-1 ---------UAGCAGCACGUAAAUAUUGGCa-------------------------------------------------- 2795 0,-1 ---------UAGCAGCACGUAAAUAUUGGCaa------------------------------------------------- 483 0,-1 ---------UAGCAGCACGUAAAUAUUGGCau------------------------------------------------- 143 0,-1 ---------UAGCAGCACGUAAAUAUUGGCc-------------------------------------------------- 48 0,-1 ---------UAGCAGCACGUAAAUAUUGGCu-------------------------------------------------- 396 0,-1 ---------UAGCAGCACGUAAAUAUUGGCuu------------------------------------------------- 22 0,-1 ---------UAGCAGCACGUAAAUAUUGGCG-------------------------------------------------- 108232 0,0 ---------UAGCAGCACGUAAAUAUUGGCGa------------------------------------------------- 9102 0,0 ---------UAGCAGCACGUAAAUAUUGGCGaa------------------------------------------------ 250 0,0 ---------UAGCAGCACGUAAAUAUUGGCGau------------------------------------------------ 201 0,0 ---------UAGCAGCACGUAAAUAUUGGCGc------------------------------------------------- 68 0,0 ---------UAGCAGCACGUAAAUAUUGGCGg------------------------------------------------- 23 0,0 ---------UAGCAGCACGUAAAUAUUGGCGU------------------------------------------------- 19522 0,1 ---------UAGCAGCACGUAAAUAUUGGCGUA------------------------------------------------ 200 0,2 ---------UAGCAGCACGUAAAUAUUGGCGUAa----------------------------------------------- 32 0,2 ---------UAGCAGCACGUAAAUAUUGGCGUAu----------------------------------------------- 41 0,2 ----------AGCAGCACGUAAAUAUUG----------------------------------------------------- 27 1,-3 ----------AGCAGCACGUAAAUAUUGG---------------------------------------------------- 253 1,-2 ----------AGCAGCACGUAAAUAUUGGa--------------------------------------------------- 21 1,-2 ----------AGCAGCACGUAAAUAUUGGaa-------------------------------------------------- 2 1,-2 ----------AGCAGCACGUAAAUAUUGGC--------------------------------------------------- 486 1,-1 ----------AGCAGCACGUAAAUAUUGGCa-------------------------------------------------- 79 1,-1 ----------AGCAGCACGUAAAUAUUGGCaa------------------------------------------------- 8 1,-1 ----------AGCAGCACGUAAAUAUUGGCc-------------------------------------------------- 2 1,-1 ----------AGCAGCACGUAAAUAUUGGCu-------------------------------------------------- 2 1,-1 ----------AGCAGCACGUAAAUAUUGGCG-------------------------------------------------- 4643 1,0 ----------AGCAGCACGUAAAUAUUGGCGa------------------------------------------------- 280 1,0 ----------AGCAGCACGUAAAUAUUGGCGaa------------------------------------------------ 2 1,0 ----------AGCAGCACGUAAAUAUUGGCGau------------------------------------------------ 2 1,0 ----------AGCAGCACGUAAAUAUUGGCGc------------------------------------------------- 2 1,0 ----------AGCAGCACGUAAAUAUUGGCGU------------------------------------------------- 765 1,1 ----------AGCAGCACGUAAAUAUUGGCGUA------------------------------------------------ 7 1,2 ----------AGCAGCACGUAAAUAUUGGCGUAa----------------------------------------------- 2 1,2 -----------GCAGCACGUAAAUAUUGG---------------------------------------------------- 12 2,-2 -----------GCAGCACGUAAAUAUUGGC--------------------------------------------------- 9 2,-1 -----------GCAGCACGUAAAUAUUGGCG-------------------------------------------------- 350 2,0 -----------GCAGCACGUAAAUAUUGGCGa------------------------------------------------- 9 2,0 -----------GCAGCACGUAAAUAUUGGCGU------------------------------------------------- 35 2,1 --------------------------------------------------CACCAAUAUUACUGUGCUGCU---------- 2 -2,-3 --------------------------------------------------CACCAAUAUUACUGUGCUGCUUU-------- 3 -2,-1 ---------------------------------------------------ACCAAUAUUACUGUGCUG------------ 2 -1,-5 ---------------------------------------------------ACCAAUAUUACUGUGCUGC----------- 6 -1,-4 ---------------------------------------------------ACCAAUAUUACUGUGCUGCU---------- 473 -1,-3 ---------------------------------------------------ACCAAUAUUACUGUGCUGCUU--------- 432 -1,-2 ---------------------------------------------------ACCAAUAUUACUGUGCUGCUUU-------- 1045 -1,-1 ---------------------------------------------------ACCAAUAUUACUGUGCUGCUUUu------- 35 -1,-1 ---------------------------------------------------ACCAAUAUUACUGUGCUGCUUUA------- 41 -1,0 ---------------------------------------------------ACCAAUAUUACUGUGCUGCUUUAu------ 2 -1,0 ----------------------------------------------------CCAAUAUUACUGUGCUGCU---------- 4 0,-3 ----------------------------------------------------CCAAUAUUACUGUGCUGCUU--------- 6 0,-2 ----------------------------------------------------CCAAUAUUACUGUGCUGCUUU-------- 50 0,-1 ----------------------------------------------------CCAAUAUUACUGUGCUGCUUUA------- 50 0,0 ----------------------------------------------------CCAAUAUUACUGUGCUGCUUUAa------ 4 0,0 ----------------------------------------------------CCAAUAUUACUGUGCUGCUUUAu------ 2 0,0 ------------------------------------------------------AAUAUUACUGUGCUGCUUU-------- 4 2,-1 >hsa-mir-17 MA:14-36;mi:51-72 Tumor gucagaauaauguCAAAGUGCUUACAGUGCAGGUAGugauaugugcaucuACUGCAGUGAAGGCACUUGUAGcauuauggugac ------------UCAAAGUGCUUACAGUGCA----------------------------------------------------- 4 -1,-5 ------------UCAAAGUGCUUACAGUGCAa---------------------------------------------------- 2 -1,-5 ------------UCAAAGUGCUUACAGUGCAG---------------------------------------------------- 104 -1,-4 ------------UCAAAGUGCUUACAGUGCAGaa-------------------------------------------------- 2 -1,-4 ------------UCAAAGUGCUUACAGUGCAGG--------------------------------------------------- 253 -1,-3 ------------UCAAAGUGCUUACAGUGCAGGa-------------------------------------------------- 84 -1,-3 ------------UCAAAGUGCUUACAGUGCAGGaa------------------------------------------------- 17 -1,-3 ------------UCAAAGUGCUUACAGUGCAGGau------------------------------------------------- 14 -1,-3 ------------UCAAAGUGCUUACAGUGCAGGc-------------------------------------------------- 4 -1,-3 ------------UCAAAGUGCUUACAGUGCAGGg-------------------------------------------------- 5 -1,-3 ------------UCAAAGUGCUUACAGUGCAGGU-------------------------------------------------- 1090 -1,-2 ------------UCAAAGUGCUUACAGUGCAGGUg------------------------------------------------- 3 -1,-2 ------------UCAAAGUGCUUACAGUGCAGGUu------------------------------------------------- 90 -1,-2 ------------UCAAAGUGCUUACAGUGCAGGUuu------------------------------------------------ 12 -1,-2 ------------UCAAAGUGCUUACAGUGCAGGUA------------------------------------------------- 601 -1,-1 ------------UCAAAGUGCUUACAGUGCAGGUAa------------------------------------------------ 86 -1,-1 ------------UCAAAGUGCUUACAGUGCAGGUAu------------------------------------------------ 131 -1,-1 ------------UCAAAGUGCUUACAGUGCAGGUAuu----------------------------------------------- 2 -1,-1 ------------UCAAAGUGCUUACAGUGCAGGUAG------------------------------------------------ 178 -1,0 ------------UCAAAGUGCUUACAGUGCAGGUAGa----------------------------------------------- 13 -1,0 ------------UCAAAGUGCUUACAGUGCAGGUAGU----------------------------------------------- 7 -1,1 -------------CAAAGUGCUUACAGUGCA----------------------------------------------------- 260 0,-5 -------------CAAAGUGCUUACAGUGCAa---------------------------------------------------- 74 0,-5 -------------CAAAGUGCUUACAGUGCAaa--------------------------------------------------- 11 0,-5 -------------CAAAGUGCUUACAGUGCAau--------------------------------------------------- 5 0,-5 -------------CAAAGUGCUUACAGUGCAu---------------------------------------------------- 12 0,-5 -------------CAAAGUGCUUACAGUGCAG---------------------------------------------------- 1705 0,-4 -------------CAAAGUGCUUACAGUGCAGa--------------------------------------------------- 150 0,-4 -------------CAAAGUGCUUACAGUGCAGaa-------------------------------------------------- 44 0,-4 -------------CAAAGUGCUUACAGUGCAGau-------------------------------------------------- 17 0,-4 -------------CAAAGUGCUUACAGUGCAGu--------------------------------------------------- 58 0,-4 -------------CAAAGUGCUUACAGUGCAGuu-------------------------------------------------- 14 0,-4 -------------CAAAGUGCUUACAGUGCAGG--------------------------------------------------- 2894 0,-3 -------------CAAAGUGCUUACAGUGCAGGa-------------------------------------------------- 776 0,-3 -------------CAAAGUGCUUACAGUGCAGGaa------------------------------------------------- 452 0,-3 -------------CAAAGUGCUUACAGUGCAGGau------------------------------------------------- 111 0,-3 -------------CAAAGUGCUUACAGUGCAGGc-------------------------------------------------- 18 0,-3 -------------CAAAGUGCUUACAGUGCAGGg-------------------------------------------------- 34 0,-3 -------------CAAAGUGCUUACAGUGCAGGU-------------------------------------------------- 8757 0,-2 -------------CAAAGUGCUUACAGUGCAGGUc------------------------------------------------- 33 0,-2 -------------CAAAGUGCUUACAGUGCAGGUg------------------------------------------------- 23 0,-2 -------------CAAAGUGCUUACAGUGCAGGUu------------------------------------------------- 639 0,-2 -------------CAAAGUGCUUACAGUGCAGGUuu------------------------------------------------ 154 0,-2 -------------CAAAGUGCUUACAGUGCAGGUA------------------------------------------------- 12619 0,-1 -------------CAAAGUGCUUACAGUGCAGGUAa------------------------------------------------ 6253 0,-1 -------------CAAAGUGCUUACAGUGCAGGUAaa----------------------------------------------- 275 0,-1 -------------CAAAGUGCUUACAGUGCAGGUAau----------------------------------------------- 156 0,-1 -------------CAAAGUGCUUACAGUGCAGGUAc------------------------------------------------ 88 0,-1 -------------CAAAGUGCUUACAGUGCAGGUAu------------------------------------------------ 6069 0,-1 -------------CAAAGUGCUUACAGUGCAGGUAuu----------------------------------------------- 127 0,-1 -------------CAAAGUGCUUACAGUGCAGGUAG------------------------------------------------ 52183 0,0 -------------CAAAGUGCUUACAGUGCAGGUAGa----------------------------------------------- 4035 0,0 -------------CAAAGUGCUUACAGUGCAGGUAGaa---------------------------------------------- 326 0,0 -------------CAAAGUGCUUACAGUGCAGGUAGau---------------------------------------------- 62 0,0 -------------CAAAGUGCUUACAGUGCAGGUAGc----------------------------------------------- 26 0,0 -------------CAAAGUGCUUACAGUGCAGGUAGg----------------------------------------------- 45 0,0 -------------CAAAGUGCUUACAGUGCAGGUAGU----------------------------------------------- 5072 0,1 -------------CAAAGUGCUUACAGUGCAGGUAGUa---------------------------------------------- 26 0,1 -------------CAAAGUGCUUACAGUGCAGGUAGUu---------------------------------------------- 50 0,1 --------------AAAGUGCUUACAGUGCAG---------------------------------------------------- 46 1,-4 --------------AAAGUGCUUACAGUGCAGa--------------------------------------------------- 3 1,-4 --------------AAAGUGCUUACAGUGCAGaa-------------------------------------------------- 4 1,-4 --------------AAAGUGCUUACAGUGCAGG--------------------------------------------------- 74 1,-3 --------------AAAGUGCUUACAGUGCAGGa-------------------------------------------------- 16 1,-3 --------------AAAGUGCUUACAGUGCAGGaa------------------------------------------------- 18 1,-3 --------------AAAGUGCUUACAGUGCAGGau------------------------------------------------- 5 1,-3 --------------AAAGUGCUUACAGUGCAGGg-------------------------------------------------- 3 1,-3 --------------AAAGUGCUUACAGUGCAGGU-------------------------------------------------- 401 1,-2 --------------AAAGUGCUUACAGUGCAGGUu------------------------------------------------- 12 1,-2 --------------AAAGUGCUUACAGUGCAGGUuu------------------------------------------------ 3 1,-2 --------------AAAGUGCUUACAGUGCAGGUA------------------------------------------------- 570 1,-1 --------------AAAGUGCUUACAGUGCAGGUAa------------------------------------------------ 276 1,-1 --------------AAAGUGCUUACAGUGCAGGUAaa----------------------------------------------- 4 1,-1 --------------AAAGUGCUUACAGUGCAGGUAc------------------------------------------------ 2 1,-1 --------------AAAGUGCUUACAGUGCAGGUAu------------------------------------------------ 252 1,-1 --------------AAAGUGCUUACAGUGCAGGUAuu----------------------------------------------- 2 1,-1 --------------AAAGUGCUUACAGUGCAGGUAG------------------------------------------------ 2482 1,0 --------------AAAGUGCUUACAGUGCAGGUAGa----------------------------------------------- 227 1,0 --------------AAAGUGCUUACAGUGCAGGUAGaa---------------------------------------------- 2 1,0 --------------AAAGUGCUUACAGUGCAGGUAGU----------------------------------------------- 222 1,1 ---------------AAGUGCUUACAGUGCAGGUAu------------------------------------------------ 2 2,-1 ---------------AAGUGCUUACAGUGCAGGUAG------------------------------------------------ 33 2,0 ---------------AAGUGCUUACAGUGCAGGUAGa----------------------------------------------- 2 2,0 --------------------------------------------------ACUGCAGUGAAGGCACUU---------------- 11 0,-4 --------------------------------------------------ACUGCAGUGAAGGCACUUG--------------- 62 0,-3 --------------------------------------------------ACUGCAGUGAAGGCACUUGa-------------- 3 0,-3 --------------------------------------------------ACUGCAGUGAAGGCACUUGU-------------- 222 0,-2 --------------------------------------------------ACUGCAGUGAAGGCACUUGUu------------- 2 0,-2 --------------------------------------------------ACUGCAGUGAAGGCACUUGUA------------- 76 0,-1 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAa------------ 109 0,-1 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAaa----------- 2 0,-1 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAu------------ 23 0,-1 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAG------------ 8596 0,0 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGa----------- 1759 0,0 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGaa---------- 56 0,0 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGau---------- 2 0,0 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGg----------- 4 0,0 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGu----------- 860 0,0 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGuu---------- 2 0,0 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGC----------- 3714 0,1 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGCu---------- 90 0,1 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGCA---------- 55 0,2 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGCAa--------- 2 0,2 --------------------------------------------------ACUGCAGUGAAGGCACUUGUAGCAU--------- 2 0,3 ---------------------------------------------------CUGCAGUGAAGGCACUUGU-------------- 2 1,-2 ---------------------------------------------------CUGCAGUGAAGGCACUUGUA------------- 2 1,-1 ---------------------------------------------------CUGCAGUGAAGGCACUUGUAu------------ 2 1,-1 ---------------------------------------------------CUGCAGUGAAGGCACUUGUAG------------ 378 1,0 ---------------------------------------------------CUGCAGUGAAGGCACUUGUAGa----------- 17 1,0 ---------------------------------------------------CUGCAGUGAAGGCACUUGUAGu----------- 24 1,0 ---------------------------------------------------CUGCAGUGAAGGCACUUGUAGC----------- 319 1,1 ---------------------------------------------------CUGCAGUGAAGGCACUUGUAGCu---------- 23 1,1 ---------------------------------------------------CUGCAGUGAAGGCACUUGUAGCA---------- 7 1,2 ----------------------------------------------------UGCAGUGAAGGCACUUGUAG------------ 9 2,0 ----------------------------------------------------UGCAGUGAAGGCACUUGUAGa----------- 5 2,0 ----------------------------------------------------UGCAGUGAAGGCACUUGUAGC----------- 4 2,1 >hsa-mir-181a-1 MA:24-46;mi:64-85 Tumor ugaguuuugagguugcuucagugAACAUUCAACGCUGUCGGUGAGUuuggaauuaaaaucaaaACCAUCGACCGUUGAUUGUACCcuauggcuaaccaucaucuacucca ----------------------GAACAUUCAACGCUGUCGGUG------------------------------------------------------------------- 5 -1,-3 ----------------------GAACAUUCAACGCUGUCGGUGA------------------------------------------------------------------ 6 -1,-2 -----------------------AACAUUCAACGCUGUCGG--------------------------------------------------------------------- 4466 0,-5 -----------------------AACAUUCAACGCUGUCGGa-------------------------------------------------------------------- 25 0,-5 -----------------------AACAUUCAACGCUGUCGGaa------------------------------------------------------------------- 7 0,-5 -----------------------AACAUUCAACGCUGUCGGg-------------------------------------------------------------------- 13 0,-5 -----------------------AACAUUCAACGCUGUCGGU-------------------------------------------------------------------- 2938 0,-4 -----------------------AACAUUCAACGCUGUCGGUa------------------------------------------------------------------- 194 0,-4 -----------------------AACAUUCAACGCUGUCGGUaa------------------------------------------------------------------ 118 0,-4 -----------------------AACAUUCAACGCUGUCGGUau------------------------------------------------------------------ 22 0,-4 -----------------------AACAUUCAACGCUGUCGGUu------------------------------------------------------------------- 113 0,-4 -----------------------AACAUUCAACGCUGUCGGUuu------------------------------------------------------------------ 2 0,-4 -----------------------AACAUUCAACGCUGUCGGUG------------------------------------------------------------------- 5137 0,-3 -----------------------AACAUUCAACGCUGUCGGUGc------------------------------------------------------------------ 42 0,-3 -----------------------AACAUUCAACGCUGUCGGUGg------------------------------------------------------------------ 13 0,-3 -----------------------AACAUUCAACGCUGUCGGUGu------------------------------------------------------------------ 813 0,-3 -----------------------AACAUUCAACGCUGUCGGUGuu----------------------------------------------------------------- 2 0,-3 -----------------------AACAUUCAACGCUGUCGGUGA------------------------------------------------------------------ 13943 0,-2 -----------------------AACAUUCAACGCUGUCGGUGAa----------------------------------------------------------------- 1364 0,-2 -----------------------AACAUUCAACGCUGUCGGUGAaa---------------------------------------------------------------- 151 0,-2 -----------------------AACAUUCAACGCUGUCGGUGAau---------------------------------------------------------------- 210 0,-2 -----------------------AACAUUCAACGCUGUCGGUGAc----------------------------------------------------------------- 12 0,-2 -----------------------AACAUUCAACGCUGUCGGUGAu----------------------------------------------------------------- 259 0,-2 -----------------------AACAUUCAACGCUGUCGGUGAuu---------------------------------------------------------------- 145 0,-2 -----------------------AACAUUCAACGCUGUCGGUGAG----------------------------------------------------------------- 19475 0,-1 -----------------------AACAUUCAACGCUGUCGGUGAGa---------------------------------------------------------------- 7619 0,-1 -----------------------AACAUUCAACGCUGUCGGUGAGaa--------------------------------------------------------------- 174 0,-1 -----------------------AACAUUCAACGCUGUCGGUGAGau--------------------------------------------------------------- 54 0,-1 -----------------------AACAUUCAACGCUGUCGGUGAGc---------------------------------------------------------------- 422 0,-1 -----------------------AACAUUCAACGCUGUCGGUGAGg---------------------------------------------------------------- 709 0,-1 -----------------------AACAUUCAACGCUGUCGGUGAGU---------------------------------------------------------------- 83071 0,0 -----------------------AACAUUCAACGCUGUCGGUGAGUa--------------------------------------------------------------- 426 0,0 -----------------------AACAUUCAACGCUGUCGGUGAGUaa-------------------------------------------------------------- 51 0,0 -----------------------AACAUUCAACGCUGUCGGUGAGUau-------------------------------------------------------------- 59 0,0 -----------------------AACAUUCAACGCUGUCGGUGAGUc--------------------------------------------------------------- 21 0,0 -----------------------AACAUUCAACGCUGUCGGUGAGUg--------------------------------------------------------------- 32 0,0 -----------------------AACAUUCAACGCUGUCGGUGAGUU--------------------------------------------------------------- 20641 0,1 -----------------------AACAUUCAACGCUGUCGGUGAGUUa-------------------------------------------------------------- 245 0,1 -----------------------AACAUUCAACGCUGUCGGUGAGUUc-------------------------------------------------------------- 27 0,1 -----------------------AACAUUCAACGCUGUCGGUGAGUUg-------------------------------------------------------------- 12 0,1 -----------------------AACAUUCAACGCUGUCGGUGAGUUU-------------------------------------------------------------- 21052 0,2 ------------------------ACAUUCAACGCUGUCGGU-------------------------------------------------------------------- 11 1,-4 ------------------------ACAUUCAACGCUGUCGGUG------------------------------------------------------------------- 29 1,-3 ------------------------ACAUUCAACGCUGUCGGUGu------------------------------------------------------------------ 8 1,-3 ------------------------ACAUUCAACGCUGUCGGUGA------------------------------------------------------------------ 206 1,-2 ------------------------ACAUUCAACGCUGUCGGUGAa----------------------------------------------------------------- 8 1,-2 ------------------------ACAUUCAACGCUGUCGGUGAG----------------------------------------------------------------- 323 1,-1 ------------------------ACAUUCAACGCUGUCGGUGAGa---------------------------------------------------------------- 106 1,-1 ------------------------ACAUUCAACGCUGUCGGUGAGU---------------------------------------------------------------- 1510 1,0 ------------------------ACAUUCAACGCUGUCGGUGAGUau-------------------------------------------------------------- 2 1,0 ------------------------ACAUUCAACGCUGUCGGUGAGUU--------------------------------------------------------------- 385 1,1 ------------------------ACAUUCAACGCUGUCGGUGAGUUU-------------------------------------------------------------- 281 1,2 ------------------------ACAUUCAACGCUGUCGGUGAGUUUu------------------------------------------------------------- 9 1,2 -------------------------CAUUCAACGCUGUCGGUG------------------------------------------------------------------- 2 2,-3 -------------------------CAUUCAACGCUGUCGGUGAG----------------------------------------------------------------- 10 2,-1 -------------------------CAUUCAACGCUGUCGGUGAGa---------------------------------------------------------------- 2 2,-1 -------------------------CAUUCAACGCUGUCGGUGAGU---------------------------------------------------------------- 68 2,0 -------------------------CAUUCAACGCUGUCGGUGAGUU--------------------------------------------------------------- 6 2,1 -------------------------CAUUCAACGCUGUCGGUGAGUUU-------------------------------------------------------------- 10 2,2 -------------------------------------------------------------AAACCAUCGACCGUUGAUUGU---------------------------- 4 -2,-3 --------------------------------------------------------------AACCAUCGACCGUUGAUUGUAa-------------------------- 3 -1,-2 --------------------------------------------------------------AACCAUCGACCGUUGAUUGUAu-------------------------- 6 -1,-2 --------------------------------------------------------------AACCAUCGACCGUUGAUUGUAC-------------------------- 14 -1,-1 ---------------------------------------------------------------ACCAUCGACCGUUGAUUG----------------------------- 4 0,-4 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGU---------------------------- 214 0,-3 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUu--------------------------- 2 0,-3 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUA--------------------------- 396 0,-2 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUAa-------------------------- 329 0,-2 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUAaa------------------------- 18 0,-2 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUAu-------------------------- 74 0,-2 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUAuu------------------------- 12 0,-2 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUAC-------------------------- 1038 0,-1 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUACa------------------------- 22 0,-1 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUACu------------------------- 72 0,-1 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUACC------------------------- 2327 0,0 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUACCa------------------------ 8 0,0 ---------------------------------------------------------------ACCAUCGACCGUUGAUUGUACCu------------------------ 23 0,0 ----------------------------------------------------------------CCAUCGACCGUUGAUUGUAC-------------------------- 6 1,-1 ----------------------------------------------------------------CCAUCGACCGUUGAUUGUACC------------------------- 12 1,0 >hsa-mir-181a-2 MA:39-61;mi:77-98 Tumor agaagggcuaucaggccagccuucagaggacuccaaggAACAUUCAACGCUGUCGGUGAGUuugggauuugaaaaaACCACUGACCGUUGACUGUACCuugggguccuua -------------------------------------GAACAUUCAACGCUGUCGGUG---------------------------------------------------- 5 -1,-3 -------------------------------------GAACAUUCAACGCUGUCGGUGA--------------------------------------------------- 6 -1,-2 --------------------------------------AACAUUCAACGCUGUCGG------------------------------------------------------ 4466 0,-5 --------------------------------------AACAUUCAACGCUGUCGGa----------------------------------------------------- 25 0,-5 --------------------------------------AACAUUCAACGCUGUCGGaa---------------------------------------------------- 7 0,-5 --------------------------------------AACAUUCAACGCUGUCGGg----------------------------------------------------- 13 0,-5 --------------------------------------AACAUUCAACGCUGUCGGU----------------------------------------------------- 2938 0,-4 --------------------------------------AACAUUCAACGCUGUCGGUa---------------------------------------------------- 194 0,-4 --------------------------------------AACAUUCAACGCUGUCGGUaa--------------------------------------------------- 118 0,-4 --------------------------------------AACAUUCAACGCUGUCGGUau--------------------------------------------------- 22 0,-4 --------------------------------------AACAUUCAACGCUGUCGGUu---------------------------------------------------- 113 0,-4 --------------------------------------AACAUUCAACGCUGUCGGUuu--------------------------------------------------- 2 0,-4 --------------------------------------AACAUUCAACGCUGUCGGUG---------------------------------------------------- 5137 0,-3 --------------------------------------AACAUUCAACGCUGUCGGUGc--------------------------------------------------- 42 0,-3 --------------------------------------AACAUUCAACGCUGUCGGUGg--------------------------------------------------- 13 0,-3 --------------------------------------AACAUUCAACGCUGUCGGUGu--------------------------------------------------- 813 0,-3 --------------------------------------AACAUUCAACGCUGUCGGUGuu-------------------------------------------------- 2 0,-3 --------------------------------------AACAUUCAACGCUGUCGGUGA--------------------------------------------------- 13943 0,-2 --------------------------------------AACAUUCAACGCUGUCGGUGAa-------------------------------------------------- 1364 0,-2 --------------------------------------AACAUUCAACGCUGUCGGUGAaa------------------------------------------------- 151 0,-2 --------------------------------------AACAUUCAACGCUGUCGGUGAau------------------------------------------------- 210 0,-2 --------------------------------------AACAUUCAACGCUGUCGGUGAc-------------------------------------------------- 12 0,-2 --------------------------------------AACAUUCAACGCUGUCGGUGAu-------------------------------------------------- 259 0,-2 --------------------------------------AACAUUCAACGCUGUCGGUGAuu------------------------------------------------- 145 0,-2 --------------------------------------AACAUUCAACGCUGUCGGUGAG-------------------------------------------------- 19475 0,-1 --------------------------------------AACAUUCAACGCUGUCGGUGAGa------------------------------------------------- 7619 0,-1 --------------------------------------AACAUUCAACGCUGUCGGUGAGaa------------------------------------------------ 174 0,-1 --------------------------------------AACAUUCAACGCUGUCGGUGAGau------------------------------------------------ 54 0,-1 --------------------------------------AACAUUCAACGCUGUCGGUGAGc------------------------------------------------- 422 0,-1 --------------------------------------AACAUUCAACGCUGUCGGUGAGg------------------------------------------------- 709 0,-1 --------------------------------------AACAUUCAACGCUGUCGGUGAGU------------------------------------------------- 83071 0,0 --------------------------------------AACAUUCAACGCUGUCGGUGAGUa------------------------------------------------ 426 0,0 --------------------------------------AACAUUCAACGCUGUCGGUGAGUaa----------------------------------------------- 51 0,0 --------------------------------------AACAUUCAACGCUGUCGGUGAGUau----------------------------------------------- 59 0,0 --------------------------------------AACAUUCAACGCUGUCGGUGAGUc------------------------------------------------ 21 0,0 --------------------------------------AACAUUCAACGCUGUCGGUGAGUg------------------------------------------------ 32 0,0 --------------------------------------AACAUUCAACGCUGUCGGUGAGUU------------------------------------------------ 20641 0,1 --------------------------------------AACAUUCAACGCUGUCGGUGAGUUa----------------------------------------------- 245 0,1 --------------------------------------AACAUUCAACGCUGUCGGUGAGUUc----------------------------------------------- 27 0,1 --------------------------------------AACAUUCAACGCUGUCGGUGAGUUg----------------------------------------------- 12 0,1 --------------------------------------AACAUUCAACGCUGUCGGUGAGUUU----------------------------------------------- 21052 0,2 ---------------------------------------ACAUUCAACGCUGUCGGU----------------------------------------------------- 11 1,-4 ---------------------------------------ACAUUCAACGCUGUCGGUG---------------------------------------------------- 29 1,-3 ---------------------------------------ACAUUCAACGCUGUCGGUGu--------------------------------------------------- 8 1,-3 ---------------------------------------ACAUUCAACGCUGUCGGUGA--------------------------------------------------- 206 1,-2 ---------------------------------------ACAUUCAACGCUGUCGGUGAa-------------------------------------------------- 8 1,-2 ---------------------------------------ACAUUCAACGCUGUCGGUGAG-------------------------------------------------- 323 1,-1 ---------------------------------------ACAUUCAACGCUGUCGGUGAGa------------------------------------------------- 106 1,-1 ---------------------------------------ACAUUCAACGCUGUCGGUGAGU------------------------------------------------- 1510 1,0 ---------------------------------------ACAUUCAACGCUGUCGGUGAGUau----------------------------------------------- 2 1,0 ---------------------------------------ACAUUCAACGCUGUCGGUGAGUU------------------------------------------------ 385 1,1 ---------------------------------------ACAUUCAACGCUGUCGGUGAGUUU----------------------------------------------- 281 1,2 ---------------------------------------ACAUUCAACGCUGUCGGUGAGUUUu---------------------------------------------- 9 1,2 ----------------------------------------CAUUCAACGCUGUCGGUG---------------------------------------------------- 2 2,-3 ----------------------------------------CAUUCAACGCUGUCGGUGAG-------------------------------------------------- 10 2,-1 ----------------------------------------CAUUCAACGCUGUCGGUGAGa------------------------------------------------- 2 2,-1 ----------------------------------------CAUUCAACGCUGUCGGUGAGU------------------------------------------------- 68 2,0 ----------------------------------------CAUUCAACGCUGUCGGUGAGUU------------------------------------------------ 6 2,1 ----------------------------------------CAUUCAACGCUGUCGGUGAGUUU----------------------------------------------- 10 2,2 ---------------------------------------------------------------------------AACCACUGACCGUUGACUGU--------------- 6 -1,-3 ---------------------------------------------------------------------------AACCACUGACCGUUGACUGUA-------------- 2 -1,-2 ---------------------------------------------------------------------------AACCACUGACCGUUGACUGUAu------------- 7 -1,-2 ---------------------------------------------------------------------------AACCACUGACCGUUGACUGUAC------------- 9 -1,-1 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGU--------------- 50 0,-3 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGUA-------------- 196 0,-2 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGUAa------------- 59 0,-2 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGUAaa------------ 8 0,-2 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGUAu------------- 25 0,-2 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGUAuu------------ 2 0,-2 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGUAC------------- 523 0,-1 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGUACa------------ 12 0,-1 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGUACu------------ 44 0,-1 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGUACC------------ 676 0,0 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGUACCa----------- 2 0,0 ----------------------------------------------------------------------------ACCACUGACCGUUGACUGUACCU----------- 2 0,1 -----------------------------------------------------------------------------CCACUGACCGUUGACUGUAC------------- 2 1,-1 >hsa-mir-181b-1 5pM:36-58 Tumor ccugugcagagauuauuuuuuaaaaggucacaaucAACAUUCAUUGCUGUCGGUGGGUugaacuguguggacaagcucacugaacaaugaaugcaacuguggccccgcuu ----------------------------------CAACAUUCAUUGCUGUCGGU-------------------------------------------------------- 2 -1,-4 ----------------------------------CAACAUUCAUUGCUGUCGGUG------------------------------------------------------- 45 -1,-3 ----------------------------------CAACAUUCAUUGCUGUCGGUGa------------------------------------------------------ 6 -1,-3 ----------------------------------CAACAUUCAUUGCUGUCGGUGu------------------------------------------------------ 2 -1,-3 ----------------------------------CAACAUUCAUUGCUGUCGGUGG------------------------------------------------------ 18 -1,-2 ----------------------------------CAACAUUCAUUGCUGUCGGUGGa----------------------------------------------------- 11 -1,-2 ----------------------------------CAACAUUCAUUGCUGUCGGUGGG----------------------------------------------------- 5 -1,-1 ----------------------------------CAACAUUCAUUGCUGUCGGUGGGa---------------------------------------------------- 4 -1,-1 ----------------------------------CAACAUUCAUUGCUGUCGGUGGGU---------------------------------------------------- 19 -1,0 ----------------------------------CAACAUUCAUUGCUGUCGGUGGGUU--------------------------------------------------- 6 -1,1 -----------------------------------AACAUUCAUUGCUGUCGG--------------------------------------------------------- 458 0,-5 -----------------------------------AACAUUCAUUGCUGUCGGa-------------------------------------------------------- 3 0,-5 -----------------------------------AACAUUCAUUGCUGUCGGaa------------------------------------------------------- 3 0,-5 -----------------------------------AACAUUCAUUGCUGUCGGg-------------------------------------------------------- 4 0,-5 -----------------------------------AACAUUCAUUGCUGUCGGU-------------------------------------------------------- 518 0,-4 -----------------------------------AACAUUCAUUGCUGUCGGUa------------------------------------------------------- 34 0,-4 -----------------------------------AACAUUCAUUGCUGUCGGUaa------------------------------------------------------ 13 0,-4 -----------------------------------AACAUUCAUUGCUGUCGGUu------------------------------------------------------- 35 0,-4 -----------------------------------AACAUUCAUUGCUGUCGGUuu------------------------------------------------------ 2 0,-4 -----------------------------------AACAUUCAUUGCUGUCGGUG------------------------------------------------------- 1204 0,-3 -----------------------------------AACAUUCAUUGCUGUCGGUGa------------------------------------------------------ 187 0,-3 -----------------------------------AACAUUCAUUGCUGUCGGUGaa----------------------------------------------------- 27 0,-3 -----------------------------------AACAUUCAUUGCUGUCGGUGu------------------------------------------------------ 253 0,-3 -----------------------------------AACAUUCAUUGCUGUCGGUGuu----------------------------------------------------- 2 0,-3 -----------------------------------AACAUUCAUUGCUGUCGGUGG------------------------------------------------------ 1154 0,-2 -----------------------------------AACAUUCAUUGCUGUCGGUGGa----------------------------------------------------- 432 0,-2 -----------------------------------AACAUUCAUUGCUGUCGGUGGaa---------------------------------------------------- 43 0,-2 -----------------------------------AACAUUCAUUGCUGUCGGUGGau---------------------------------------------------- 51 0,-2 -----------------------------------AACAUUCAUUGCUGUCGGUGGu----------------------------------------------------- 47 0,-2 -----------------------------------AACAUUCAUUGCUGUCGGUGGuu---------------------------------------------------- 2 0,-2 -----------------------------------AACAUUCAUUGCUGUCGGUGGG----------------------------------------------------- 1317 0,-1 -----------------------------------AACAUUCAUUGCUGUCGGUGGGa---------------------------------------------------- 877 0,-1 -----------------------------------AACAUUCAUUGCUGUCGGUGGGaa--------------------------------------------------- 69 0,-1 -----------------------------------AACAUUCAUUGCUGUCGGUGGGau--------------------------------------------------- 130 0,-1 -----------------------------------AACAUUCAUUGCUGUCGGUGGGc---------------------------------------------------- 16 0,-1 -----------------------------------AACAUUCAUUGCUGUCGGUGGGg---------------------------------------------------- 261 0,-1 -----------------------------------AACAUUCAUUGCUGUCGGUGGGU---------------------------------------------------- 7177 0,0 -----------------------------------AACAUUCAUUGCUGUCGGUGGGUa--------------------------------------------------- 272 0,0 -----------------------------------AACAUUCAUUGCUGUCGGUGGGUaa-------------------------------------------------- 16 0,0 -----------------------------------AACAUUCAUUGCUGUCGGUGGGUau-------------------------------------------------- 169 0,0 -----------------------------------AACAUUCAUUGCUGUCGGUGGGUc--------------------------------------------------- 2 0,0 -----------------------------------AACAUUCAUUGCUGUCGGUGGGUg--------------------------------------------------- 6 0,0 -----------------------------------AACAUUCAUUGCUGUCGGUGGGUU--------------------------------------------------- 6510 0,1 -----------------------------------AACAUUCAUUGCUGUCGGUGGGUUa-------------------------------------------------- 71 0,1 -----------------------------------AACAUUCAUUGCUGUCGGUGGGUUc-------------------------------------------------- 2 0,1 -----------------------------------AACAUUCAUUGCUGUCGGUGGGUUG-------------------------------------------------- 2 0,2 ------------------------------------ACAUUCAUUGCUGUCGGU-------------------------------------------------------- 6 1,-4 ------------------------------------ACAUUCAUUGCUGUCGGUG------------------------------------------------------- 15 1,-3 ------------------------------------ACAUUCAUUGCUGUCGGUGa------------------------------------------------------ 4 1,-3 ------------------------------------ACAUUCAUUGCUGUCGGUGu------------------------------------------------------ 4 1,-3 ------------------------------------ACAUUCAUUGCUGUCGGUGG------------------------------------------------------ 43 1,-2 ------------------------------------ACAUUCAUUGCUGUCGGUGGa----------------------------------------------------- 7 1,-2 ------------------------------------ACAUUCAUUGCUGUCGGUGGau---------------------------------------------------- 2 1,-2 ------------------------------------ACAUUCAUUGCUGUCGGUGGG----------------------------------------------------- 14 1,-1 ------------------------------------ACAUUCAUUGCUGUCGGUGGGa---------------------------------------------------- 20 1,-1 ------------------------------------ACAUUCAUUGCUGUCGGUGGGU---------------------------------------------------- 207 1,0 ------------------------------------ACAUUCAUUGCUGUCGGUGGGUa--------------------------------------------------- 22 1,0 ------------------------------------ACAUUCAUUGCUGUCGGUGGGUaa-------------------------------------------------- 4 1,0 ------------------------------------ACAUUCAUUGCUGUCGGUGGGUau-------------------------------------------------- 2 1,0 ------------------------------------ACAUUCAUUGCUGUCGGUGGGUU--------------------------------------------------- 234 1,1 -------------------------------------CAUUCAUUGCUGUCGGUGGGU---------------------------------------------------- 2 2,0 -------------------------------------CAUUCAUUGCUGUCGGUGGGUU--------------------------------------------------- 4 2,1 ---------------------------------------------------------------------------CUCACUGAACAAUGAAUGC---------------- 2 ---------------------------------------------------------------------------CUCACUGAACAAUGAAUGCA--------------- 37 ---------------------------------------------------------------------------CUCACUGAACAAUGAAUGCAu-------------- 2 ---------------------------------------------------------------------------CUCACUGAACAAUGAAUGCAA-------------- 38 ---------------------------------------------------------------------------CUCACUGAACAAUGAAUGCAAu------------- 6 >hsa-mir-181b-2 5pM:16-38 Tumor cugauggcugcacucAACAUUCAUUGCUGUCGGUGGGUuugagucugaaucaacucacugaucaaugaaugcaaacugcggaccaaaca --------------CAACAUUCAUUGCUGUCGGU------------------------------------------------------- 2 -1,-4 --------------CAACAUUCAUUGCUGUCGGUG------------------------------------------------------ 45 -1,-3 --------------CAACAUUCAUUGCUGUCGGUGa----------------------------------------------------- 6 -1,-3 --------------CAACAUUCAUUGCUGUCGGUGu----------------------------------------------------- 2 -1,-3 --------------CAACAUUCAUUGCUGUCGGUGG----------------------------------------------------- 18 -1,-2 --------------CAACAUUCAUUGCUGUCGGUGGa---------------------------------------------------- 11 -1,-2 --------------CAACAUUCAUUGCUGUCGGUGGG---------------------------------------------------- 5 -1,-1 --------------CAACAUUCAUUGCUGUCGGUGGGa--------------------------------------------------- 4 -1,-1 --------------CAACAUUCAUUGCUGUCGGUGGGU--------------------------------------------------- 19 -1,0 --------------CAACAUUCAUUGCUGUCGGUGGGUU-------------------------------------------------- 6 -1,1 ---------------AACAUUCAUUGCUGUCGG-------------------------------------------------------- 458 0,-5 ---------------AACAUUCAUUGCUGUCGGa------------------------------------------------------- 3 0,-5 ---------------AACAUUCAUUGCUGUCGGaa------------------------------------------------------ 3 0,-5 ---------------AACAUUCAUUGCUGUCGGg------------------------------------------------------- 4 0,-5 ---------------AACAUUCAUUGCUGUCGGU------------------------------------------------------- 518 0,-4 ---------------AACAUUCAUUGCUGUCGGUa------------------------------------------------------ 34 0,-4 ---------------AACAUUCAUUGCUGUCGGUaa----------------------------------------------------- 13 0,-4 ---------------AACAUUCAUUGCUGUCGGUu------------------------------------------------------ 35 0,-4 ---------------AACAUUCAUUGCUGUCGGUuu----------------------------------------------------- 2 0,-4 ---------------AACAUUCAUUGCUGUCGGUG------------------------------------------------------ 1204 0,-3 ---------------AACAUUCAUUGCUGUCGGUGa----------------------------------------------------- 187 0,-3 ---------------AACAUUCAUUGCUGUCGGUGaa---------------------------------------------------- 27 0,-3 ---------------AACAUUCAUUGCUGUCGGUGu----------------------------------------------------- 253 0,-3 ---------------AACAUUCAUUGCUGUCGGUGuu---------------------------------------------------- 2 0,-3 ---------------AACAUUCAUUGCUGUCGGUGG----------------------------------------------------- 1154 0,-2 ---------------AACAUUCAUUGCUGUCGGUGGa---------------------------------------------------- 432 0,-2 ---------------AACAUUCAUUGCUGUCGGUGGaa--------------------------------------------------- 43 0,-2 ---------------AACAUUCAUUGCUGUCGGUGGau--------------------------------------------------- 51 0,-2 ---------------AACAUUCAUUGCUGUCGGUGGu---------------------------------------------------- 47 0,-2 ---------------AACAUUCAUUGCUGUCGGUGGuu--------------------------------------------------- 2 0,-2 ---------------AACAUUCAUUGCUGUCGGUGGG---------------------------------------------------- 1317 0,-1 ---------------AACAUUCAUUGCUGUCGGUGGGa--------------------------------------------------- 877 0,-1 ---------------AACAUUCAUUGCUGUCGGUGGGaa-------------------------------------------------- 69 0,-1 ---------------AACAUUCAUUGCUGUCGGUGGGau-------------------------------------------------- 130 0,-1 ---------------AACAUUCAUUGCUGUCGGUGGGc--------------------------------------------------- 16 0,-1 ---------------AACAUUCAUUGCUGUCGGUGGGg--------------------------------------------------- 261 0,-1 ---------------AACAUUCAUUGCUGUCGGUGGGU--------------------------------------------------- 7177 0,0 ---------------AACAUUCAUUGCUGUCGGUGGGUa-------------------------------------------------- 272 0,0 ---------------AACAUUCAUUGCUGUCGGUGGGUaa------------------------------------------------- 16 0,0 ---------------AACAUUCAUUGCUGUCGGUGGGUau------------------------------------------------- 169 0,0 ---------------AACAUUCAUUGCUGUCGGUGGGUc-------------------------------------------------- 2 0,0 ---------------AACAUUCAUUGCUGUCGGUGGGUg-------------------------------------------------- 6 0,0 ---------------AACAUUCAUUGCUGUCGGUGGGUU-------------------------------------------------- 6510 0,1 ---------------AACAUUCAUUGCUGUCGGUGGGUUa------------------------------------------------- 71 0,1 ---------------AACAUUCAUUGCUGUCGGUGGGUUc------------------------------------------------- 2 0,1 ---------------AACAUUCAUUGCUGUCGGUGGGUUU------------------------------------------------- 2564 0,2 ----------------ACAUUCAUUGCUGUCGGU------------------------------------------------------- 6 1,-4 ----------------ACAUUCAUUGCUGUCGGUG------------------------------------------------------ 15 1,-3 ----------------ACAUUCAUUGCUGUCGGUGa----------------------------------------------------- 4 1,-3 ----------------ACAUUCAUUGCUGUCGGUGu----------------------------------------------------- 4 1,-3 ----------------ACAUUCAUUGCUGUCGGUGG----------------------------------------------------- 43 1,-2 ----------------ACAUUCAUUGCUGUCGGUGGa---------------------------------------------------- 7 1,-2 ----------------ACAUUCAUUGCUGUCGGUGGau--------------------------------------------------- 2 1,-2 ----------------ACAUUCAUUGCUGUCGGUGGG---------------------------------------------------- 14 1,-1 ----------------ACAUUCAUUGCUGUCGGUGGGa--------------------------------------------------- 20 1,-1 ----------------ACAUUCAUUGCUGUCGGUGGGU--------------------------------------------------- 207 1,0 ----------------ACAUUCAUUGCUGUCGGUGGGUa-------------------------------------------------- 22 1,0 ----------------ACAUUCAUUGCUGUCGGUGGGUaa------------------------------------------------- 4 1,0 ----------------ACAUUCAUUGCUGUCGGUGGGUau------------------------------------------------- 2 1,0 ----------------ACAUUCAUUGCUGUCGGUGGGUU-------------------------------------------------- 234 1,1 ----------------ACAUUCAUUGCUGUCGGUGGGUUU------------------------------------------------- 57 1,2 ----------------ACAUUCAUUGCUGUCGGUGGGUUUu------------------------------------------------ 7 1,2 -----------------CAUUCAUUGCUGUCGGUGGGU--------------------------------------------------- 2 2,0 -----------------CAUUCAUUGCUGUCGGUGGGUU-------------------------------------------------- 4 2,1 -----------------------------------------------------CUCACUGAUCAAUGAAUGC----------------- 2 -----------------------------------------------------CUCACUGAUCAAUGAAUGCA---------------- 7 -----------------------------------------------------CUCACUGAUCAAUGAAUGCAA--------------- 3 -----------------------------------------------------CUCACUGAUCAAUGAAUGCAAA-------------- 4 >hsa-mir-181c MA:27-48;mi:65-86 Tumor cggaaaauuugccaaggguuugggggAACAUUCAACCUGUCGGUGAGUuugggcagcucaggcaAACCAUCGACCGUUGAGUGGACccugaggccuggaauugccauccu --------------------------AACAUUCAACCUGUCGGU------------------------------------------------------------------ 29 0,-4 --------------------------AACAUUCAACCUGUCGGUa----------------------------------------------------------------- 3 0,-4 --------------------------AACAUUCAACCUGUCGGUG----------------------------------------------------------------- 90 0,-3 --------------------------AACAUUCAACCUGUCGGUGu---------------------------------------------------------------- 3 0,-3 --------------------------AACAUUCAACCUGUCGGUGA---------------------------------------------------------------- 98 0,-2 --------------------------AACAUUCAACCUGUCGGUGAa--------------------------------------------------------------- 14 0,-2 --------------------------AACAUUCAACCUGUCGGUGAaa-------------------------------------------------------------- 2 0,-2 --------------------------AACAUUCAACCUGUCGGUGAau-------------------------------------------------------------- 8 0,-2 --------------------------AACAUUCAACCUGUCGGUGAu--------------------------------------------------------------- 3 0,-2 --------------------------AACAUUCAACCUGUCGGUGAuu-------------------------------------------------------------- 8 0,-2 --------------------------AACAUUCAACCUGUCGGUGAG--------------------------------------------------------------- 404 0,-1 --------------------------AACAUUCAACCUGUCGGUGAGa-------------------------------------------------------------- 112 0,-1 --------------------------AACAUUCAACCUGUCGGUGAGaa------------------------------------------------------------- 6 0,-1 --------------------------AACAUUCAACCUGUCGGUGAGau------------------------------------------------------------- 6 0,-1 --------------------------AACAUUCAACCUGUCGGUGAGc-------------------------------------------------------------- 12 0,-1 --------------------------AACAUUCAACCUGUCGGUGAGg-------------------------------------------------------------- 29 0,-1 --------------------------AACAUUCAACCUGUCGGUGAGU-------------------------------------------------------------- 7468 0,0 --------------------------AACAUUCAACCUGUCGGUGAGUa------------------------------------------------------------- 21 0,0 --------------------------AACAUUCAACCUGUCGGUGAGUaa------------------------------------------------------------ 4 0,0 --------------------------AACAUUCAACCUGUCGGUGAGUau------------------------------------------------------------ 7 0,0 --------------------------AACAUUCAACCUGUCGGUGAGUc------------------------------------------------------------- 4 0,0 --------------------------AACAUUCAACCUGUCGGUGAGUU------------------------------------------------------------- 4804 0,1 --------------------------AACAUUCAACCUGUCGGUGAGUUa------------------------------------------------------------ 60 0,1 --------------------------AACAUUCAACCUGUCGGUGAGUUaa----------------------------------------------------------- 4 0,1 --------------------------AACAUUCAACCUGUCGGUGAGUUau----------------------------------------------------------- 2 0,1 --------------------------AACAUUCAACCUGUCGGUGAGUUc------------------------------------------------------------ 7 0,1 --------------------------AACAUUCAACCUGUCGGUGAGUUg------------------------------------------------------------ 5 0,1 --------------------------AACAUUCAACCUGUCGGUGAGUUU------------------------------------------------------------ 4072 0,2 --------------------------AACAUUCAACCUGUCGGUGAGUUUa----------------------------------------------------------- 5 0,2 --------------------------AACAUUCAACCUGUCGGUGAGUUUu----------------------------------------------------------- 128 0,2 --------------------------AACAUUCAACCUGUCGGUGAGUUUG----------------------------------------------------------- 12 0,3 ---------------------------ACAUUCAACCUGUCGGUG----------------------------------------------------------------- 2 1,-3 ---------------------------ACAUUCAACCUGUCGGUGAG--------------------------------------------------------------- 4 1,-1 ---------------------------ACAUUCAACCUGUCGGUGAGa-------------------------------------------------------------- 4 1,-1 ---------------------------ACAUUCAACCUGUCGGUGAGU-------------------------------------------------------------- 167 1,0 ---------------------------ACAUUCAACCUGUCGGUGAGUU------------------------------------------------------------- 75 1,1 ---------------------------ACAUUCAACCUGUCGGUGAGUUU------------------------------------------------------------ 52 1,2 ----------------------------CAUUCAACCUGUCGGUGAGU-------------------------------------------------------------- 2 2,0 ----------------------------------------------------------------AACCAUCGACCGUUGAGUGGA------------------------- 6 0,-1 ----------------------------------------------------------------AACCAUCGACCGUUGAGUGGAu------------------------ 2 0,-1 ----------------------------------------------------------------AACCAUCGACCGUUGAGUGGAC------------------------ 14 0,0 ----------------------------------------------------------------AACCAUCGACCGUUGAGUGGACu----------------------- 2 0,0 -----------------------------------------------------------------ACCAUCGACCGUUGAGUG--------------------------- 3 1,-3 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGG-------------------------- 14 1,-2 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGA------------------------- 148 1,-1 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGAa------------------------ 47 1,-1 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGAaa----------------------- 10 1,-1 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGAu------------------------ 2 1,-1 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGAC------------------------ 662 1,0 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGACa----------------------- 148 1,0 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGACaa---------------------- 4 1,0 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGACu----------------------- 211 1,0 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGACC----------------------- 588 1,1 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGACCa---------------------- 7 1,1 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGACCu---------------------- 4 1,1 -----------------------------------------------------------------ACCAUCGACCGUUGAGUGGACCuu--------------------- 4 1,1 ------------------------------------------------------------------CCAUCGACCGUUGAGUGGAa------------------------ 2 2,-1 ------------------------------------------------------------------CCAUCGACCGUUGAGUGGAC------------------------ 6 2,0 >hsa-mir-181d 5pM:36-58 Tumor guccccuccccuaggccacagccgaggucacaaucAACAUUCAUUGUUGUCGGUGGGUugugaggacugaggccagacccaccgggggaugaaugucacuguggcugggccagacacggcuuaaggggaauggggac -----------------------------------AACAUUCAUUGUUGUCGG------------------------------------------------------------------------------------ 47 0,-5 -----------------------------------AACAUUCAUUGUUGUCGGU----------------------------------------------------------------------------------- 32 0,-4 -----------------------------------AACAUUCAUUGUUGUCGGUa---------------------------------------------------------------------------------- 2 0,-4 -----------------------------------AACAUUCAUUGUUGUCGGUaa--------------------------------------------------------------------------------- 2 0,-4 -----------------------------------AACAUUCAUUGUUGUCGGUu---------------------------------------------------------------------------------- 2 0,-4 -----------------------------------AACAUUCAUUGUUGUCGGUG---------------------------------------------------------------------------------- 113 0,-3 -----------------------------------AACAUUCAUUGUUGUCGGUGa--------------------------------------------------------------------------------- 24 0,-3 -----------------------------------AACAUUCAUUGUUGUCGGUGaa-------------------------------------------------------------------------------- 8 0,-3 -----------------------------------AACAUUCAUUGUUGUCGGUGau-------------------------------------------------------------------------------- 2 0,-3 -----------------------------------AACAUUCAUUGUUGUCGGUGu--------------------------------------------------------------------------------- 14 0,-3 -----------------------------------AACAUUCAUUGUUGUCGGUGG--------------------------------------------------------------------------------- 488 0,-2 -----------------------------------AACAUUCAUUGUUGUCGGUGGa-------------------------------------------------------------------------------- 76 0,-2 -----------------------------------AACAUUCAUUGUUGUCGGUGGaa------------------------------------------------------------------------------- 10 0,-2 -----------------------------------AACAUUCAUUGUUGUCGGUGGau------------------------------------------------------------------------------- 5 0,-2 -----------------------------------AACAUUCAUUGUUGUCGGUGGu-------------------------------------------------------------------------------- 9 0,-2 -----------------------------------AACAUUCAUUGUUGUCGGUGGG-------------------------------------------------------------------------------- 294 0,-1 -----------------------------------AACAUUCAUUGUUGUCGGUGGGa------------------------------------------------------------------------------- 166 0,-1 -----------------------------------AACAUUCAUUGUUGUCGGUGGGaa------------------------------------------------------------------------------ 12 0,-1 -----------------------------------AACAUUCAUUGUUGUCGGUGGGau------------------------------------------------------------------------------ 7 0,-1 -----------------------------------AACAUUCAUUGUUGUCGGUGGGc------------------------------------------------------------------------------- 8 0,-1 -----------------------------------AACAUUCAUUGUUGUCGGUGGGg------------------------------------------------------------------------------- 33 0,-1 -----------------------------------AACAUUCAUUGUUGUCGGUGGGU------------------------------------------------------------------------------- 2196 0,0 -----------------------------------AACAUUCAUUGUUGUCGGUGGGUa------------------------------------------------------------------------------ 62 0,0 -----------------------------------AACAUUCAUUGUUGUCGGUGGGUaa----------------------------------------------------------------------------- 2 0,0 -----------------------------------AACAUUCAUUGUUGUCGGUGGGUau----------------------------------------------------------------------------- 24 0,0 -----------------------------------AACAUUCAUUGUUGUCGGUGGGUg------------------------------------------------------------------------------ 6 0,0 -----------------------------------AACAUUCAUUGUUGUCGGUGGGUU------------------------------------------------------------------------------ 1831 0,1 -----------------------------------AACAUUCAUUGUUGUCGGUGGGUUa----------------------------------------------------------------------------- 11 0,1 -----------------------------------AACAUUCAUUGUUGUCGGUGGGUUc----------------------------------------------------------------------------- 2 0,1 -----------------------------------AACAUUCAUUGUUGUCGGUGGGUUu----------------------------------------------------------------------------- 462 0,1 -----------------------------------AACAUUCAUUGUUGUCGGUGGGUUG----------------------------------------------------------------------------- 3 0,2 ------------------------------------ACAUUCAUUGUUGUCGGUG---------------------------------------------------------------------------------- 2 1,-3 ------------------------------------ACAUUCAUUGUUGUCGGUGu--------------------------------------------------------------------------------- 2 1,-3 ------------------------------------ACAUUCAUUGUUGUCGGUGG--------------------------------------------------------------------------------- 16 1,-2 ------------------------------------ACAUUCAUUGUUGUCGGUGGG-------------------------------------------------------------------------------- 4 1,-1 ------------------------------------ACAUUCAUUGUUGUCGGUGGGa------------------------------------------------------------------------------- 3 1,-1 ------------------------------------ACAUUCAUUGUUGUCGGUGGGU------------------------------------------------------------------------------- 52 1,0 ------------------------------------ACAUUCAUUGUUGUCGGUGGGUU------------------------------------------------------------------------------ 21 1,1 ------------------------------------ACAUUCAUUGUUGUCGGUGGGUUu----------------------------------------------------------------------------- 11 1,1 ------------------------------------ACAUUCAUUGUUGUCGGUGGGUUuu---------------------------------------------------------------------------- 2 1,1 >hsa-mir-182 MA:23-46;mi:67-87 Tumor gagcugcuugccuccccccguuUUUGGCAAUGGUAGAACUCACACUggugagguaacaggauccggUGGUUCUAGACUUGCCAACUAuggggcgaggacucagccggcac ----------------------UUUGGCAAUGGUAGAACUC--------------------------------------------------------------------- 726 0,-5 ----------------------UUUGGCAAUGGUAGAACUCc-------------------------------------------------------------------- 9 0,-5 ----------------------UUUGGCAAUGGUAGAACUCg-------------------------------------------------------------------- 2 0,-5 ----------------------UUUGGCAAUGGUAGAACUCu-------------------------------------------------------------------- 8 0,-5 ----------------------UUUGGCAAUGGUAGAACUCA-------------------------------------------------------------------- 5719 0,-4 ----------------------UUUGGCAAUGGUAGAACUCAa------------------------------------------------------------------- 112 0,-4 ----------------------UUUGGCAAUGGUAGAACUCAaa------------------------------------------------------------------ 75 0,-4 ----------------------UUUGGCAAUGGUAGAACUCAau------------------------------------------------------------------ 2 0,-4 ----------------------UUUGGCAAUGGUAGAACUCAg------------------------------------------------------------------- 4 0,-4 ----------------------UUUGGCAAUGGUAGAACUCAu------------------------------------------------------------------- 40 0,-4 ----------------------UUUGGCAAUGGUAGAACUCAC------------------------------------------------------------------- 4255 0,-3 ----------------------UUUGGCAAUGGUAGAACUCACc------------------------------------------------------------------ 212 0,-3 ----------------------UUUGGCAAUGGUAGAACUCACg------------------------------------------------------------------ 16 0,-3 ----------------------UUUGGCAAUGGUAGAACUCACu------------------------------------------------------------------ 112 0,-3 ----------------------UUUGGCAAUGGUAGAACUCACA------------------------------------------------------------------ 16444 0,-2 ----------------------UUUGGCAAUGGUAGAACUCACAa----------------------------------------------------------------- 332 0,-2 ----------------------UUUGGCAAUGGUAGAACUCACAau---------------------------------------------------------------- 152 0,-2 ----------------------UUUGGCAAUGGUAGAACUCACAg----------------------------------------------------------------- 6 0,-2 ----------------------UUUGGCAAUGGUAGAACUCACAu----------------------------------------------------------------- 81 0,-2 ----------------------UUUGGCAAUGGUAGAACUCACAuu---------------------------------------------------------------- 55 0,-2 ----------------------UUUGGCAAUGGUAGAACUCACAC----------------------------------------------------------------- 5298 0,-1 ----------------------UUUGGCAAUGGUAGAACUCACACa---------------------------------------------------------------- 76 0,-1 ----------------------UUUGGCAAUGGUAGAACUCACACc---------------------------------------------------------------- 38 0,-1 ----------------------UUUGGCAAUGGUAGAACUCACACg---------------------------------------------------------------- 5 0,-1 ----------------------UUUGGCAAUGGUAGAACUCACACU---------------------------------------------------------------- 24606 0,0 ----------------------UUUGGCAAUGGUAGAACUCACACUa--------------------------------------------------------------- 17 0,0 ----------------------UUUGGCAAUGGUAGAACUCACACUc--------------------------------------------------------------- 2 0,0 ----------------------UUUGGCAAUGGUAGAACUCACACUu--------------------------------------------------------------- 55 0,0 ----------------------UUUGGCAAUGGUAGAACUCACACUG--------------------------------------------------------------- 3785 0,1 -----------------------UUGGCAAUGGUAGAACUC--------------------------------------------------------------------- 4 1,-5 -----------------------UUGGCAAUGGUAGAACUCA-------------------------------------------------------------------- 83 1,-4 -----------------------UUGGCAAUGGUAGAACUCAC------------------------------------------------------------------- 72 1,-3 -----------------------UUGGCAAUGGUAGAACUCACc------------------------------------------------------------------ 3 1,-3 -----------------------UUGGCAAUGGUAGAACUCACA------------------------------------------------------------------ 304 1,-2 -----------------------UUGGCAAUGGUAGAACUCACAa----------------------------------------------------------------- 2 1,-2 -----------------------UUGGCAAUGGUAGAACUCACAC----------------------------------------------------------------- 56 1,-1 -----------------------UUGGCAAUGGUAGAACUCACACU---------------------------------------------------------------- 480 1,0 -----------------------UUGGCAAUGGUAGAACUCACACUa--------------------------------------------------------------- 2 1,0 -----------------------UUGGCAAUGGUAGAACUCACACUG--------------------------------------------------------------- 55 1,1 -----------------------UUGGCAAUGGUAGAACUCACACUGu-------------------------------------------------------------- 2 1,1 -----------------------UUGGCAAUGGUAGAACUCACACUGG-------------------------------------------------------------- 38 1,2 ------------------------UGGCAAUGGUAGAACUCACA------------------------------------------------------------------ 18 2,-2 ------------------------UGGCAAUGGUAGAACUCACACU---------------------------------------------------------------- 26 2,0 ----------------------------------------------------------------GGUGGUUCUAGACUUGCCA--------------------------- 2 -2,-4 ----------------------------------------------------------------GGUGGUUCUAGACUUGCCAA-------------------------- 2 -2,-3 ----------------------------------------------------------------GGUGGUUCUAGACUUGCCAAC------------------------- 20 -2,-2 ----------------------------------------------------------------GGUGGUUCUAGACUUGCCAACU------------------------ 156 -2,-1 ----------------------------------------------------------------GGUGGUUCUAGACUUGCCAACUA----------------------- 2 -2,0 ----------------------------------------------------------------GGUGGUUCUAGACUUGCCAACUAU---------------------- 4 -2,1 -----------------------------------------------------------------GUGGUUCUAGACUUGCCAACU------------------------ 2 -1,-1 -----------------------------------------------------------------GUGGUUCUAGACUUGCCAACUA----------------------- 5 -1,0 ------------------------------------------------------------------UGGUUCUAGACUUGCCAAC------------------------- 4 0,-2 ------------------------------------------------------------------UGGUUCUAGACUUGCCAACU------------------------ 171 0,-1 ------------------------------------------------------------------UGGUUCUAGACUUGCCAACUu----------------------- 2 0,-1 ------------------------------------------------------------------UGGUUCUAGACUUGCCAACUA----------------------- 17 0,0 ------------------------------------------------------------------UGGUUCUAGACUUGCCAACUAU---------------------- 7 0,1 >hsa-mir-1827 3pM:49-66 Tumor ucagcagcacagccuucagccuaaagcaaugagaagccucugaaaggcUGAGGCAGUAGAUUGAAU ------------------------------------------------UGAGGCAGUAGAUUGAAU 2 0,0 >hsa-mir-183 MA:27-48;mi:66-87 Tumor ccgcagagugugacuccuguucugugUAUGGCACUGGUAGAAUUCACUgugaacagucucagucaGUGAAUUACCGAAGGGCCAUAAacagagcagagacagauccacga ------------------------UGUAUGGCACUGGUAGAAUU------------------------------------------------------------------ 2 -2,-4 ------------------------UGUAUGGCACUGGUAGAAUUC----------------------------------------------------------------- 6 -2,-3 ------------------------UGUAUGGCACUGGUAGAAUUCA---------------------------------------------------------------- 28 -2,-2 ------------------------UGUAUGGCACUGGUAGAAUUCAC--------------------------------------------------------------- 4 -2,-1 ------------------------UGUAUGGCACUGGUAGAAUUCACU-------------------------------------------------------------- 15 -2,0 -------------------------GUAUGGCACUGGUAGAAUUC----------------------------------------------------------------- 2 -1,-3 -------------------------GUAUGGCACUGGUAGAAUUCA---------------------------------------------------------------- 2 -1,-2 -------------------------GUAUGGCACUGGUAGAAUUCAC--------------------------------------------------------------- 4 -1,-1 -------------------------GUAUGGCACUGGUAGAAUUCACU-------------------------------------------------------------- 24 -1,0 -------------------------GUAUGGCACUGGUAGAAUUCACUGU------------------------------------------------------------ 2 -1,2 --------------------------UAUGGCACUGGUAGAAUU------------------------------------------------------------------ 165 0,-4 --------------------------UAUGGCACUGGUAGAAUUa----------------------------------------------------------------- 20 0,-4 --------------------------UAUGGCACUGGUAGAAUUaa---------------------------------------------------------------- 2 0,-4 --------------------------UAUGGCACUGGUAGAAUUu----------------------------------------------------------------- 10 0,-4 --------------------------UAUGGCACUGGUAGAAUUC----------------------------------------------------------------- 277 0,-3 --------------------------UAUGGCACUGGUAGAAUUCA---------------------------------------------------------------- 1379 0,-2 --------------------------UAUGGCACUGGUAGAAUUCAa--------------------------------------------------------------- 26 0,-2 --------------------------UAUGGCACUGGUAGAAUUCAau-------------------------------------------------------------- 47 0,-2 --------------------------UAUGGCACUGGUAGAAUUCAg--------------------------------------------------------------- 2 0,-2 --------------------------UAUGGCACUGGUAGAAUUCAu--------------------------------------------------------------- 4 0,-2 --------------------------UAUGGCACUGGUAGAAUUCAuu-------------------------------------------------------------- 16 0,-2 --------------------------UAUGGCACUGGUAGAAUUCAC--------------------------------------------------------------- 705 0,-1 --------------------------UAUGGCACUGGUAGAAUUCACa-------------------------------------------------------------- 18 0,-1 --------------------------UAUGGCACUGGUAGAAUUCACc-------------------------------------------------------------- 12 0,-1 --------------------------UAUGGCACUGGUAGAAUUCACg-------------------------------------------------------------- 2 0,-1 --------------------------UAUGGCACUGGUAGAAUUCACU-------------------------------------------------------------- 12753 0,0 --------------------------UAUGGCACUGGUAGAAUUCACUa------------------------------------------------------------- 29 0,0 --------------------------UAUGGCACUGGUAGAAUUCACUu------------------------------------------------------------- 38 0,0 --------------------------UAUGGCACUGGUAGAAUUCACUuu------------------------------------------------------------ 2 0,0 --------------------------UAUGGCACUGGUAGAAUUCACUG------------------------------------------------------------- 4466 0,1 --------------------------UAUGGCACUGGUAGAAUUCACUGa------------------------------------------------------------ 99 0,1 --------------------------UAUGGCACUGGUAGAAUUCACUGc------------------------------------------------------------ 2 0,1 --------------------------UAUGGCACUGGUAGAAUUCACUGU------------------------------------------------------------ 792 0,2 --------------------------UAUGGCACUGGUAGAAUUCACUGUu----------------------------------------------------------- 2 0,2 --------------------------UAUGGCACUGGUAGAAUUCACUGUG----------------------------------------------------------- 9 0,3 ---------------------------AUGGCACUGGUAGAAUUC----------------------------------------------------------------- 114 1,-3 ---------------------------AUGGCACUGGUAGAAUUCA---------------------------------------------------------------- 540 1,-2 ---------------------------AUGGCACUGGUAGAAUUCAa--------------------------------------------------------------- 4 1,-2 ---------------------------AUGGCACUGGUAGAAUUCAau-------------------------------------------------------------- 17 1,-2 ---------------------------AUGGCACUGGUAGAAUUCAu--------------------------------------------------------------- 2 1,-2 ---------------------------AUGGCACUGGUAGAAUUCAuu-------------------------------------------------------------- 12 1,-2 ---------------------------AUGGCACUGGUAGAAUUCAC--------------------------------------------------------------- 391 1,-1 ---------------------------AUGGCACUGGUAGAAUUCACa-------------------------------------------------------------- 4 1,-1 ---------------------------AUGGCACUGGUAGAAUUCACc-------------------------------------------------------------- 4 1,-1 ---------------------------AUGGCACUGGUAGAAUUCACg-------------------------------------------------------------- 4 1,-1 ---------------------------AUGGCACUGGUAGAAUUCACU-------------------------------------------------------------- 8628 1,0 ---------------------------AUGGCACUGGUAGAAUUCACUa------------------------------------------------------------- 22 1,0 ---------------------------AUGGCACUGGUAGAAUUCACUu------------------------------------------------------------- 27 1,0 ---------------------------AUGGCACUGGUAGAAUUCACUG------------------------------------------------------------- 6916 1,1 ---------------------------AUGGCACUGGUAGAAUUCACUGa------------------------------------------------------------ 632 1,1 ---------------------------AUGGCACUGGUAGAAUUCACUGaa----------------------------------------------------------- 2 1,1 ---------------------------AUGGCACUGGUAGAAUUCACUGc------------------------------------------------------------ 8 1,1 ---------------------------AUGGCACUGGUAGAAUUCACUGU------------------------------------------------------------ 2578 1,2 ---------------------------AUGGCACUGGUAGAAUUCACUGUu----------------------------------------------------------- 29 1,2 ----------------------------UGGCACUGGUAGAAUUCACU-------------------------------------------------------------- 24 2,0 ----------------------------UGGCACUGGUAGAAUUCACUG------------------------------------------------------------- 15 2,1 ----------------------------UGGCACUGGUAGAAUUCACUGU------------------------------------------------------------ 3 2,2 -----------------------------------------------------------------GUGAAUUACCGAAGGGCCAU------------------------- 3 0,-2 -----------------------------------------------------------------GUGAAUUACCGAAGGGCCAUA------------------------ 7 0,-1 -----------------------------------------------------------------GUGAAUUACCGAAGGGCCAUAA----------------------- 12 0,0 -----------------------------------------------------------------GUGAAUUACCGAAGGGCCAUAAu---------------------- 4 0,0 ------------------------------------------------------------------UGAAUUACCGAAGGGCCAU------------------------- 44 1,-2 ------------------------------------------------------------------UGAAUUACCGAAGGGCCAUu------------------------ 12 1,-2 ------------------------------------------------------------------UGAAUUACCGAAGGGCCAUA------------------------ 38 1,-1 ------------------------------------------------------------------UGAAUUACCGAAGGGCCAUAu----------------------- 13 1,-1 ------------------------------------------------------------------UGAAUUACCGAAGGGCCAUAuu---------------------- 2 1,-1 ------------------------------------------------------------------UGAAUUACCGAAGGGCCAUAA----------------------- 197 1,0 ------------------------------------------------------------------UGAAUUACCGAAGGGCCAUAAu---------------------- 108 1,0 ------------------------------------------------------------------UGAAUUACCGAAGGGCCAUAAuu--------------------- 2 1,0 ------------------------------------------------------------------UGAAUUACCGAAGGGCCAUAAA---------------------- 137 1,1 ------------------------------------------------------------------UGAAUUACCGAAGGGCCAUAAAa--------------------- 5 1,1 ------------------------------------------------------------------UGAAUUACCGAAGGGCCAUAAAu--------------------- 7 1,1 -------------------------------------------------------------------GAAUUACCGAAGGGCCAUAAA---------------------- 2 2,1 >hsa-mir-184 3pM:53-74 Tumor ccagucacguccccuuaucacuuuuccagcccagcuuugugacuguaaguguUGGACGGAGAACUGAUAAGGGUaggugauuga ------------CCUUAUCACUUUUCCAGCCCAGu------------------------------------------------- 3 ------------CCUUAUCACUUUUCCAGCCCAGC------------------------------------------------- 8 ---------------------------------------------------UUGGACGGAGAACUGAUAA-------------- 2 -1,-4 ---------------------------------------------------UUGGACGGAGAACUGAUAAGG------------ 9 -1,-2 ---------------------------------------------------UUGGACGGAGAACUGAUAAGGa----------- 3 -1,-2 ---------------------------------------------------UUGGACGGAGAACUGAUAAGGG----------- 5 -1,-1 ---------------------------------------------------UUGGACGGAGAACUGAUAAGGGU---------- 20 -1,0 ----------------------------------------------------UGGACGGAGAACUGAUAA-------------- 122 0,-4 ----------------------------------------------------UGGACGGAGAACUGAUAAa------------- 19 0,-4 ----------------------------------------------------UGGACGGAGAACUGAUAAaa------------ 8 0,-4 ----------------------------------------------------UGGACGGAGAACUGAUAAu------------- 7 0,-4 ----------------------------------------------------UGGACGGAGAACUGAUAAuu------------ 2 0,-4 ----------------------------------------------------UGGACGGAGAACUGAUAAG------------- 939 0,-3 ----------------------------------------------------UGGACGGAGAACUGAUAAGa------------ 52 0,-3 ----------------------------------------------------UGGACGGAGAACUGAUAAGaa----------- 3 0,-3 ----------------------------------------------------UGGACGGAGAACUGAUAAGu------------ 25 0,-3 ----------------------------------------------------UGGACGGAGAACUGAUAAGuu----------- 5 0,-3 ----------------------------------------------------UGGACGGAGAACUGAUAAGG------------ 3861 0,-2 ----------------------------------------------------UGGACGGAGAACUGAUAAGGa----------- 321 0,-2 ----------------------------------------------------UGGACGGAGAACUGAUAAGGaa---------- 83 0,-2 ----------------------------------------------------UGGACGGAGAACUGAUAAGGau---------- 46 0,-2 ----------------------------------------------------UGGACGGAGAACUGAUAAGGc----------- 4 0,-2 ----------------------------------------------------UGGACGGAGAACUGAUAAGGu----------- 143 0,-2 ----------------------------------------------------UGGACGGAGAACUGAUAAGGuu---------- 21 0,-2 ----------------------------------------------------UGGACGGAGAACUGAUAAGGG----------- 2454 0,-1 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGa---------- 1219 0,-1 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGaa--------- 198 0,-1 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGau--------- 105 0,-1 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGc---------- 52 0,-1 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGg---------- 36 0,-1 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGU---------- 14415 0,0 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGUc--------- 6 0,0 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGUg--------- 15 0,0 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGUu--------- 2424 0,0 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGUuu-------- 840 0,0 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGUA--------- 552 0,1 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGUAa-------- 137 0,1 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGUAc-------- 4 0,1 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGUAu-------- 399 0,1 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGUAuu------- 3 0,1 ----------------------------------------------------UGGACGGAGAACUGAUAAGGGUAG-------- 3 0,2 -----------------------------------------------------GGACGGAGAACUGAUAAG------------- 14 1,-3 -----------------------------------------------------GGACGGAGAACUGAUAAGG------------ 134 1,-2 -----------------------------------------------------GGACGGAGAACUGAUAAGGa----------- 16 1,-2 -----------------------------------------------------GGACGGAGAACUGAUAAGGau---------- 2 1,-2 -----------------------------------------------------GGACGGAGAACUGAUAAGGu----------- 4 1,-2 -----------------------------------------------------GGACGGAGAACUGAUAAGGG----------- 99 1,-1 -----------------------------------------------------GGACGGAGAACUGAUAAGGGa---------- 40 1,-1 -----------------------------------------------------GGACGGAGAACUGAUAAGGGaa--------- 8 1,-1 -----------------------------------------------------GGACGGAGAACUGAUAAGGGau--------- 2 1,-1 -----------------------------------------------------GGACGGAGAACUGAUAAGGGg---------- 4 1,-1 -----------------------------------------------------GGACGGAGAACUGAUAAGGGU---------- 602 1,0 -----------------------------------------------------GGACGGAGAACUGAUAAGGGUu--------- 111 1,0 -----------------------------------------------------GGACGGAGAACUGAUAAGGGUuu-------- 36 1,0 -----------------------------------------------------GGACGGAGAACUGAUAAGGGUA--------- 20 1,1 -----------------------------------------------------GGACGGAGAACUGAUAAGGGUAa-------- 3 1,1 -----------------------------------------------------GGACGGAGAACUGAUAAGGGUAu-------- 22 1,1 ------------------------------------------------------GACGGAGAACUGAUAAGGGU---------- 3 2,0 ------------------------------------------------------GACGGAGAACUGAUAAGGGUu--------- 3 2,0 ------------------------------------------------------GACGGAGAACUGAUAAGGGUA--------- 2 2,1 ------------------------------------------------------GACGGAGAACUGAUAAGGGUAG-------- 2 2,2 >hsa-mir-185 MA:15-36;mi:50-71 Tumor agggggcgagggauUGGAGAGAAAGGCAGUUCCUGAugguccccuccccAGGGGCUGGCUUUCCUCUGGUCcuucccuccca --------------UGGAGAGAAAGGCAGUUC-------------------------------------------------- 47 0,-4 --------------UGGAGAGAAAGGCAGUUCC------------------------------------------------- 88 0,-3 --------------UGGAGAGAAAGGCAGUUCCU------------------------------------------------ 622 0,-2 --------------UGGAGAGAAAGGCAGUUCCUa----------------------------------------------- 12 0,-2 --------------UGGAGAGAAAGGCAGUUCCUaa---------------------------------------------- 38 0,-2 --------------UGGAGAGAAAGGCAGUUCCUu----------------------------------------------- 6 0,-2 --------------UGGAGAGAAAGGCAGUUCCUG----------------------------------------------- 1483 0,-1 --------------UGGAGAGAAAGGCAGUUCCUGc---------------------------------------------- 151 0,-1 --------------UGGAGAGAAAGGCAGUUCCUGg---------------------------------------------- 21 0,-1 --------------UGGAGAGAAAGGCAGUUCCUGu---------------------------------------------- 568 0,-1 --------------UGGAGAGAAAGGCAGUUCCUGuu--------------------------------------------- 66 0,-1 --------------UGGAGAGAAAGGCAGUUCCUGA---------------------------------------------- 18615 0,0 --------------UGGAGAGAAAGGCAGUUCCUGAa--------------------------------------------- 3366 0,0 --------------UGGAGAGAAAGGCAGUUCCUGAaa-------------------------------------------- 733 0,0 --------------UGGAGAGAAAGGCAGUUCCUGAau-------------------------------------------- 424 0,0 --------------UGGAGAGAAAGGCAGUUCCUGAc--------------------------------------------- 14 0,0 --------------UGGAGAGAAAGGCAGUUCCUGAg--------------------------------------------- 100 0,0 --------------UGGAGAGAAAGGCAGUUCCUGAU--------------------------------------------- 2794 0,1 --------------UGGAGAGAAAGGCAGUUCCUGAUa-------------------------------------------- 80 0,1 --------------UGGAGAGAAAGGCAGUUCCUGAUaa------------------------------------------- 2 0,1 --------------UGGAGAGAAAGGCAGUUCCUGAUu-------------------------------------------- 167 0,1 ---------------GGAGAGAAAGGCAGUUCCUG----------------------------------------------- 19 1,-1 ---------------GGAGAGAAAGGCAGUUCCUGu---------------------------------------------- 17 1,-1 ---------------GGAGAGAAAGGCAGUUCCUGA---------------------------------------------- 564 1,0 ---------------GGAGAGAAAGGCAGUUCCUGAa--------------------------------------------- 76 1,0 ---------------GGAGAGAAAGGCAGUUCCUGAaa-------------------------------------------- 10 1,0 ---------------GGAGAGAAAGGCAGUUCCUGAau-------------------------------------------- 7 1,0 ---------------GGAGAGAAAGGCAGUUCCUGAU--------------------------------------------- 75 1,1 ---------------GGAGAGAAAGGCAGUUCCUGAUu-------------------------------------------- 2 1,1 ----------------GAGAGAAAGGCAGUUCCUGA---------------------------------------------- 11 2,0 ----------------GAGAGAAAGGCAGUUCCUGAU--------------------------------------------- 2 2,1 ------------------------------------------------CAGGGGCUGGCUUUCCUCUGG------------- 8 -1,-2 ------------------------------------------------CAGGGGCUGGCUUUCCUCUGGU------------ 52 -1,-1 ------------------------------------------------CAGGGGCUGGCUUUCCUCUGGUa----------- 8 -1,-1 -------------------------------------------------AGGGGCUGGCUUUCCUCUGG------------- 16 0,-2 -------------------------------------------------AGGGGCUGGCUUUCCUCUGGa------------ 2 0,-2 -------------------------------------------------AGGGGCUGGCUUUCCUCUGGU------------ 267 0,-1 -------------------------------------------------AGGGGCUGGCUUUCCUCUGGUa----------- 13 0,-1 -------------------------------------------------AGGGGCUGGCUUUCCUCUGGUaa---------- 14 0,-1 -------------------------------------------------AGGGGCUGGCUUUCCUCUGGUau---------- 6 0,-1 -------------------------------------------------AGGGGCUGGCUUUCCUCUGGUu----------- 38 0,-1 -------------------------------------------------AGGGGCUGGCUUUCCUCUGGUuu---------- 2 0,-1 --------------------------------------------------GGGGCUGGCUUUCCUCUGGU------------ 8 1,-1 >hsa-mir-186 MA:15-36;mi:54-75 Tumor ugcuuguaacuuucCAAAGAAUUCUCCUUUUGGGCUuucugguuuuauuuuaaGCCCAAAGGUGAAUUUUUUGGGaaguuugagcu -------------CCAAAGAAUUCUCCUUUUGGG---------------------------------------------------- 9 -1,-2 -------------CCAAAGAAUUCUCCUUUUGGGa--------------------------------------------------- 2 -1,-2 -------------CCAAAGAAUUCUCCUUUUGGGaa-------------------------------------------------- 2 -1,-2 -------------CCAAAGAAUUCUCCUUUUGGGC--------------------------------------------------- 56 -1,-1 -------------CCAAAGAAUUCUCCUUUUGGGCU-------------------------------------------------- 94 -1,0 -------------CCAAAGAAUUCUCCUUUUGGGCUU------------------------------------------------- 19 -1,1 -------------CCAAAGAAUUCUCCUUUUGGGCUUU------------------------------------------------ 8 -1,2 --------------CAAAGAAUUCUCCUUUUG------------------------------------------------------ 820 0,-4 --------------CAAAGAAUUCUCCUUUUGa----------------------------------------------------- 6 0,-4 --------------CAAAGAAUUCUCCUUUUGaa---------------------------------------------------- 2 0,-4 --------------CAAAGAAUUCUCCUUUUGG----------------------------------------------------- 1326 0,-3 --------------CAAAGAAUUCUCCUUUUGGa---------------------------------------------------- 81 0,-3 --------------CAAAGAAUUCUCCUUUUGGaa--------------------------------------------------- 33 0,-3 --------------CAAAGAAUUCUCCUUUUGGu---------------------------------------------------- 15 0,-3 --------------CAAAGAAUUCUCCUUUUGGG---------------------------------------------------- 2961 0,-2 --------------CAAAGAAUUCUCCUUUUGGGa--------------------------------------------------- 1367 0,-2 --------------CAAAGAAUUCUCCUUUUGGGaa-------------------------------------------------- 855 0,-2 --------------CAAAGAAUUCUCCUUUUGGGau-------------------------------------------------- 54 0,-2 --------------CAAAGAAUUCUCCUUUUGGGu--------------------------------------------------- 60 0,-2 --------------CAAAGAAUUCUCCUUUUGGGuu-------------------------------------------------- 25 0,-2 --------------CAAAGAAUUCUCCUUUUGGGC--------------------------------------------------- 5030 0,-1 --------------CAAAGAAUUCUCCUUUUGGGCa-------------------------------------------------- 1311 0,-1 --------------CAAAGAAUUCUCCUUUUGGGCaa------------------------------------------------- 423 0,-1 --------------CAAAGAAUUCUCCUUUUGGGCau------------------------------------------------- 194 0,-1 --------------CAAAGAAUUCUCCUUUUGGGCc-------------------------------------------------- 19 0,-1 --------------CAAAGAAUUCUCCUUUUGGGCg-------------------------------------------------- 24 0,-1 --------------CAAAGAAUUCUCCUUUUGGGCU-------------------------------------------------- 29928 0,0 --------------CAAAGAAUUCUCCUUUUGGGCUa------------------------------------------------- 519 0,0 --------------CAAAGAAUUCUCCUUUUGGGCUaa------------------------------------------------ 31 0,0 --------------CAAAGAAUUCUCCUUUUGGGCUau------------------------------------------------ 158 0,0 --------------CAAAGAAUUCUCCUUUUGGGCUc------------------------------------------------- 16 0,0 --------------CAAAGAAUUCUCCUUUUGGGCUg------------------------------------------------- 38 0,0 --------------CAAAGAAUUCUCCUUUUGGGCUU------------------------------------------------- 19959 0,1 --------------CAAAGAAUUCUCCUUUUGGGCUUa------------------------------------------------ 329 0,1 --------------CAAAGAAUUCUCCUUUUGGGCUUaa----------------------------------------------- 22 0,1 --------------CAAAGAAUUCUCCUUUUGGGCUUau----------------------------------------------- 24 0,1 --------------CAAAGAAUUCUCCUUUUGGGCUUc------------------------------------------------ 4 0,1 --------------CAAAGAAUUCUCCUUUUGGGCUUg------------------------------------------------ 4 0,1 --------------CAAAGAAUUCUCCUUUUGGGCUUU------------------------------------------------ 4942 0,2 --------------CAAAGAAUUCUCCUUUUGGGCUUUa----------------------------------------------- 16 0,2 --------------CAAAGAAUUCUCCUUUUGGGCUUUu----------------------------------------------- 441 0,2 ---------------AAAGAAUUCUCCUUUUGG----------------------------------------------------- 18 1,-3 ---------------AAAGAAUUCUCCUUUUGGG---------------------------------------------------- 110 1,-2 ---------------AAAGAAUUCUCCUUUUGGGa--------------------------------------------------- 33 1,-2 ---------------AAAGAAUUCUCCUUUUGGGaa-------------------------------------------------- 31 1,-2 ---------------AAAGAAUUCUCCUUUUGGGC--------------------------------------------------- 255 1,-1 ---------------AAAGAAUUCUCCUUUUGGGCa-------------------------------------------------- 62 1,-1 ---------------AAAGAAUUCUCCUUUUGGGCaa------------------------------------------------- 9 1,-1 ---------------AAAGAAUUCUCCUUUUGGGCau------------------------------------------------- 6 1,-1 ---------------AAAGAAUUCUCCUUUUGGGCU-------------------------------------------------- 1680 1,0 ---------------AAAGAAUUCUCCUUUUGGGCUa------------------------------------------------- 27 1,0 ---------------AAAGAAUUCUCCUUUUGGGCUau------------------------------------------------ 2 1,0 ---------------AAAGAAUUCUCCUUUUGGGCUU------------------------------------------------- 1374 1,1 ---------------AAAGAAUUCUCCUUUUGGGCUUa------------------------------------------------ 8 1,1 ---------------AAAGAAUUCUCCUUUUGGGCUUau----------------------------------------------- 4 1,1 ---------------AAAGAAUUCUCCUUUUGGGCUUU------------------------------------------------ 357 1,2 ---------------AAAGAAUUCUCCUUUUGGGCUUUa----------------------------------------------- 2 1,2 ---------------AAAGAAUUCUCCUUUUGGGCUUUu----------------------------------------------- 30 1,2 ----------------AAGAAUUCUCCUUUUGGGCU-------------------------------------------------- 6 2,0 ----------------AAGAAUUCUCCUUUUGGGCUU------------------------------------------------- 4 2,1 -----------------------------------------------------GCCCAAAGGUGAAUUUUUUG------------- 4 0,-2 -----------------------------------------------------GCCCAAAGGUGAAUUUUUUGG------------ 16 0,-1 -----------------------------------------------------GCCCAAAGGUGAAUUUUUUGGa----------- 4 0,-1 -----------------------------------------------------GCCCAAAGGUGAAUUUUUUGGG----------- 9 0,0 -----------------------------------------------------GCCCAAAGGUGAAUUUUUUGGGA---------- 2 0,1 ------------------------------------------------------CCCAAAGGUGAAUUUUUUGGGA---------- 2 1,1 -------------------------------------------------------CCAAAGGUGAAUUUUUUGGGA---------- 4 2,1 >hsa-mir-187 mi:35-56;MA:71-92 Tumor ggucgggcucaccaugacacagugugagaccucgGGCUACAACACAGGACCCGGGCgcugcucugaccccUCGUGUCUUGUGUUGCAGCCGGagggacgcagguccgca ---------------------------------------------------------------------CUCGUGUCUUGUGUUGCAGCC------------------- 2 -1,-2 ---------------------------------------------------------------------CUCGUGUCUUGUGUUGCAGCCG------------------ 9 -1,-1 ---------------------------------------------------------------------CUCGUGUCUUGUGUUGCAGCCGa----------------- 2 -1,-1 ---------------------------------------------------------------------CUCGUGUCUUGUGUUGCAGCCGu----------------- 3 -1,-1 ---------------------------------------------------------------------CUCGUGUCUUGUGUUGCAGCCGG----------------- 3 -1,0 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAG--------------------- 14 0,-4 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGa-------------------- 2 0,-4 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGu-------------------- 2 0,-4 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGC-------------------- 29 0,-3 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCa------------------- 7 0,-3 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCaa------------------ 3 0,-3 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCC------------------- 51 0,-2 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCa------------------ 6 0,-2 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCu------------------ 2 0,-2 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCG------------------ 202 0,-1 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCGa----------------- 47 0,-1 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCGaa---------------- 3 0,-1 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCGau---------------- 4 0,-1 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCGu----------------- 89 0,-1 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCGuu---------------- 44 0,-1 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCGG----------------- 459 0,0 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCGGu---------------- 344 0,0 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCGGuu--------------- 138 0,0 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCGGA---------------- 155 0,1 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCGGAa--------------- 15 0,1 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCGGAu--------------- 41 0,1 ----------------------------------------------------------------------UCGUGUCUUGUGUUGCAGCCGGAuu-------------- 2 0,1 -----------------------------------------------------------------------CGUGUCUUGUGUUGCAGCCG------------------ 2 1,-1 -----------------------------------------------------------------------CGUGUCUUGUGUUGCAGCCGa----------------- 2 1,-1 -----------------------------------------------------------------------CGUGUCUUGUGUUGCAGCCGuu---------------- 2 1,-1 -----------------------------------------------------------------------CGUGUCUUGUGUUGCAGCCGG----------------- 38 1,0 -----------------------------------------------------------------------CGUGUCUUGUGUUGCAGCCGGu---------------- 92 1,0 -----------------------------------------------------------------------CGUGUCUUGUGUUGCAGCCGGuu--------------- 54 1,0 -----------------------------------------------------------------------CGUGUCUUGUGUUGCAGCCGGA---------------- 7 1,1 -----------------------------------------------------------------------CGUGUCUUGUGUUGCAGCCGGAau-------------- 2 1,1 ------------------------------------------------------------------------GUGUCUUGUGUUGCAGCCGGu---------------- 2 2,0 >hsa-mir-188 5p:15-35;3p:54-74 Tumor ugcucccucucucaCAUCCCUUGCAUGGUGGAGGGugagcuuucugaaaacccCUCCCACAUGCAGGGUUUGCAggauggcgagcc --------------CAUCCCUUGCAUGGUGGA------------------------------------------------------ 4 0,-3 --------------CAUCCCUUGCAUGGUGGAG----------------------------------------------------- 30 0,-2 --------------CAUCCCUUGCAUGGUGGAGa---------------------------------------------------- 8 0,-2 --------------CAUCCCUUGCAUGGUGGAGG---------------------------------------------------- 75 0,-1 --------------CAUCCCUUGCAUGGUGGAGGa--------------------------------------------------- 4 0,-1 --------------CAUCCCUUGCAUGGUGGAGGaa-------------------------------------------------- 2 0,-1 --------------CAUCCCUUGCAUGGUGGAGGG--------------------------------------------------- 78 0,0 --------------CAUCCCUUGCAUGGUGGAGGGa-------------------------------------------------- 67 0,0 --------------CAUCCCUUGCAUGGUGGAGGGaa------------------------------------------------- 2 0,0 --------------CAUCCCUUGCAUGGUGGAGGGau------------------------------------------------- 2 0,0 --------------CAUCCCUUGCAUGGUGGAGGGU-------------------------------------------------- 417 0,1 --------------CAUCCCUUGCAUGGUGGAGGGUa------------------------------------------------- 37 0,1 --------------CAUCCCUUGCAUGGUGGAGGGUaa------------------------------------------------ 4 0,1 --------------CAUCCCUUGCAUGGUGGAGGGUau------------------------------------------------ 3 0,1 --------------CAUCCCUUGCAUGGUGGAGGGUu------------------------------------------------- 142 0,1 ---------------AUCCCUUGCAUGGUGGAGG---------------------------------------------------- 2 1,-1 ---------------AUCCCUUGCAUGGUGGAGGG--------------------------------------------------- 2 1,0 ---------------AUCCCUUGCAUGGUGGAGGGU-------------------------------------------------- 11 1,1 ----------------------------------------------------CCUCCCACAUGCAGGGUUUGCA------------ 2 -1,0 -----------------------------------------------------CUCCCACAUGCAGGGUUUGa------------- 2 0,-2 -----------------------------------------------------CUCCCACAUGCAGGGUUUGCA------------ 51 0,0 >hsa-mir-18a MA:6-28;mi:47-69 Tumor uguucUAAGGUGCAUCUAGUGCAGAUAGugaaguagauuagcaucuACUGCCCUAAGUGCUCCUUCUGGca ----CUAAGGUGCAUCUAGUGCAGAU--------------------------------------------- 2 -1,-2 ----CUAAGGUGCAUCUAGUGCAGAUA-------------------------------------------- 7 -1,-1 ----CUAAGGUGCAUCUAGUGCAGAUAG------------------------------------------- 6 -1,0 -----UAAGGUGCAUCUAGUGCA------------------------------------------------ 23 0,-5 -----UAAGGUGCAUCUAGUGCAa----------------------------------------------- 7 0,-5 -----UAAGGUGCAUCUAGUGCAu----------------------------------------------- 2 0,-5 -----UAAGGUGCAUCUAGUGCAG----------------------------------------------- 197 0,-4 -----UAAGGUGCAUCUAGUGCAGc---------------------------------------------- 2 0,-4 -----UAAGGUGCAUCUAGUGCAGA---------------------------------------------- 1165 0,-3 -----UAAGGUGCAUCUAGUGCAGAa--------------------------------------------- 148 0,-3 -----UAAGGUGCAUCUAGUGCAGAaa-------------------------------------------- 89 0,-3 -----UAAGGUGCAUCUAGUGCAGAau-------------------------------------------- 31 0,-3 -----UAAGGUGCAUCUAGUGCAGAc--------------------------------------------- 7 0,-3 -----UAAGGUGCAUCUAGUGCAGAg--------------------------------------------- 2 0,-3 -----UAAGGUGCAUCUAGUGCAGAU--------------------------------------------- 5437 0,-2 -----UAAGGUGCAUCUAGUGCAGAUc-------------------------------------------- 4 0,-2 -----UAAGGUGCAUCUAGUGCAGAUg-------------------------------------------- 14 0,-2 -----UAAGGUGCAUCUAGUGCAGAUu-------------------------------------------- 243 0,-2 -----UAAGGUGCAUCUAGUGCAGAUA-------------------------------------------- 3654 0,-1 -----UAAGGUGCAUCUAGUGCAGAUAa------------------------------------------- 187 0,-1 -----UAAGGUGCAUCUAGUGCAGAUAaa------------------------------------------ 4 0,-1 -----UAAGGUGCAUCUAGUGCAGAUAc------------------------------------------- 2 0,-1 -----UAAGGUGCAUCUAGUGCAGAUAu------------------------------------------- 111 0,-1 -----UAAGGUGCAUCUAGUGCAGAUAG------------------------------------------- 4808 0,0 -----UAAGGUGCAUCUAGUGCAGAUAGa------------------------------------------ 332 0,0 -----UAAGGUGCAUCUAGUGCAGAUAGaa----------------------------------------- 17 0,0 -----UAAGGUGCAUCUAGUGCAGAUAGU------------------------------------------ 210 0,1 ------AAGGUGCAUCUAGUGCAGA---------------------------------------------- 11 1,-3 ------AAGGUGCAUCUAGUGCAGAU--------------------------------------------- 146 1,-2 ------AAGGUGCAUCUAGUGCAGAUu-------------------------------------------- 2 1,-2 ------AAGGUGCAUCUAGUGCAGAUA-------------------------------------------- 81 1,-1 ------AAGGUGCAUCUAGUGCAGAUAG------------------------------------------- 149 1,0 ------AAGGUGCAUCUAGUGCAGAUAGa------------------------------------------ 4 1,0 ------AAGGUGCAUCUAGUGCAGAUAGU------------------------------------------ 4 1,1 -------AGGUGCAUCUAGUGCAGAU--------------------------------------------- 6 2,-2 -------AGGUGCAUCUAGUGCAGAUAG------------------------------------------- 4 2,0 ----------------------------------------------ACUGCCCUAAGUGCUCCUU------ 9 0,-4 ----------------------------------------------ACUGCCCUAAGUGCUCCUUC----- 2 0,-3 ----------------------------------------------ACUGCCCUAAGUGCUCCUUCU---- 70 0,-2 ----------------------------------------------ACUGCCCUAAGUGCUCCUUCUa--- 2 0,-2 ----------------------------------------------ACUGCCCUAAGUGCUCCUUCUG--- 30 0,-1 ----------------------------------------------ACUGCCCUAAGUGCUCCUUCUGa-- 13 0,-1 ----------------------------------------------ACUGCCCUAAGUGCUCCUUCUGu-- 29 0,-1 ----------------------------------------------ACUGCCCUAAGUGCUCCUUCUGG-- 160 0,0 ----------------------------------------------ACUGCCCUAAGUGCUCCUUCUGGa- 4 0,0 ----------------------------------------------ACUGCCCUAAGUGCUCCUUCUGGu- 2 0,0 ----------------------------------------------ACUGCCCUAAGUGCUCCUUCUGGC- 6 0,1 -----------------------------------------------CUGCCCUAAGUGCUCCUUCUGaa- 2 1,-1 >hsa-mir-18b MA:6-28;mi:49-70 Tumor uguguUAAGGUGCAUCUAGUGCAGUUAGugaagcagcuuagaaucuacUGCCCUAAAUGCCCCUUCUGGCa -----UAAGGUGCAUCUAGUGCA------------------------------------------------ 23 0,-5 -----UAAGGUGCAUCUAGUGCAa----------------------------------------------- 7 0,-5 -----UAAGGUGCAUCUAGUGCAu----------------------------------------------- 2 0,-5 -----UAAGGUGCAUCUAGUGCAG----------------------------------------------- 197 0,-4 -----UAAGGUGCAUCUAGUGCAGc---------------------------------------------- 2 0,-4 -----UAAGGUGCAUCUAGUGCAGU---------------------------------------------- 93 0,-3 -----UAAGGUGCAUCUAGUGCAGUaa-------------------------------------------- 3 0,-3 -----UAAGGUGCAUCUAGUGCAGUU--------------------------------------------- 160 0,-2 -----UAAGGUGCAUCUAGUGCAGUUu-------------------------------------------- 11 0,-2 -----UAAGGUGCAUCUAGUGCAGUUA-------------------------------------------- 93 0,-1 -----UAAGGUGCAUCUAGUGCAGUUAa------------------------------------------- 4 0,-1 -----UAAGGUGCAUCUAGUGCAGUUAu------------------------------------------- 9 0,-1 -----UAAGGUGCAUCUAGUGCAGUUAG------------------------------------------- 114 0,0 -----UAAGGUGCAUCUAGUGCAGUUAGa------------------------------------------ 4 0,0 -----UAAGGUGCAUCUAGUGCAGUUAGU------------------------------------------ 6 0,1 ------AAGGUGCAUCUAGUGCAGU---------------------------------------------- 3 1,-3 ------AAGGUGCAUCUAGUGCAGUU--------------------------------------------- 2 1,-2 ------AAGGUGCAUCUAGUGCAGUUA-------------------------------------------- 2 1,-1 >hsa-mir-190 5pM:15-36 Tumor ugcaggccucugugUGAUAUGUUUGAUAUAUUAGGUuguuauuuaauccaacuauauaucaaacauauuccuacagugucuugcc --------------UGAUAUGUUUGAUAUAUU----------------------------------------------------- 2 0,-4 --------------UGAUAUGUUUGAUAUAUUA---------------------------------------------------- 18 0,-3 --------------UGAUAUGUUUGAUAUAUUAG--------------------------------------------------- 28 0,-2 --------------UGAUAUGUUUGAUAUAUUAGa-------------------------------------------------- 5 0,-2 --------------UGAUAUGUUUGAUAUAUUAGuu------------------------------------------------- 2 0,-2 --------------UGAUAUGUUUGAUAUAUUAGG-------------------------------------------------- 369 0,-1 --------------UGAUAUGUUUGAUAUAUUAGGa------------------------------------------------- 141 0,-1 --------------UGAUAUGUUUGAUAUAUUAGGaa------------------------------------------------ 9 0,-1 --------------UGAUAUGUUUGAUAUAUUAGGU------------------------------------------------- 1234 0,0 --------------UGAUAUGUUUGAUAUAUUAGGUa------------------------------------------------ 137 0,0 --------------UGAUAUGUUUGAUAUAUUAGGUaa----------------------------------------------- 9 0,0 --------------UGAUAUGUUUGAUAUAUUAGGUg------------------------------------------------ 2 0,0 --------------UGAUAUGUUUGAUAUAUUAGGUU------------------------------------------------ 2937 0,1 --------------UGAUAUGUUUGAUAUAUUAGGUUa----------------------------------------------- 39 0,1 --------------UGAUAUGUUUGAUAUAUUAGGUUu----------------------------------------------- 47 0,1 --------------UGAUAUGUUUGAUAUAUUAGGUUG----------------------------------------------- 384 0,2 --------------UGAUAUGUUUGAUAUAUUAGGUUGa---------------------------------------------- 6 0,2 --------------UGAUAUGUUUGAUAUAUUAGGUUGU---------------------------------------------- 13 0,3 ---------------GAUAUGUUUGAUAUAUUAGGU------------------------------------------------- 2 1,0 ---------------GAUAUGUUUGAUAUAUUAGGUU------------------------------------------------ 39 1,1 --------------------------------------------------ACUAUAUAUCAAACAUAUU---------------- 6 --------------------------------------------------ACUAUAUAUCAAACAUAUUC--------------- 14 --------------------------------------------------ACUAUAUAUCAAACAUAUUCC-------------- 15 --------------------------------------------------ACUAUAUAUCAAACAUAUUCCU------------- 94 ---------------------------------------------------CUAUAUAUCAAACAUAUUCCU------------- 4 >hsa-mir-190b 5pM:11-31 Tumor ugcuucugugUGAUAUGUUUGAUAUUGGGUUguuuaauuaggaaccaacuaaaugucaaacauauucuuacagcagcag ----------UGAUAUGUUUGAUAUUGG--------------------------------------------------- 28 0,-3 ----------UGAUAUGUUUGAUAUUGGG-------------------------------------------------- 15 0,-2 ----------UGAUAUGUUUGAUAUUGGGa------------------------------------------------- 7 0,-2 ----------UGAUAUGUUUGAUAUUGGGaa------------------------------------------------ 4 0,-2 ----------UGAUAUGUUUGAUAUUGGGU------------------------------------------------- 186 0,-1 ----------UGAUAUGUUUGAUAUUGGGUa------------------------------------------------ 16 0,-1 ----------UGAUAUGUUUGAUAUUGGGUaa----------------------------------------------- 16 0,-1 ----------UGAUAUGUUUGAUAUUGGGUU------------------------------------------------ 720 0,0 ----------UGAUAUGUUUGAUAUUGGGUUa----------------------------------------------- 103 0,0 ----------UGAUAUGUUUGAUAUUGGGUUaa---------------------------------------------- 23 0,0 ----------UGAUAUGUUUGAUAUUGGGUUau---------------------------------------------- 4 0,0 ----------UGAUAUGUUUGAUAUUGGGUUu----------------------------------------------- 242 0,0 ----------UGAUAUGUUUGAUAUUGGGUUuu---------------------------------------------- 8 0,0 ----------UGAUAUGUUUGAUAUUGGGUUG----------------------------------------------- 6187 0,1 ----------UGAUAUGUUUGAUAUUGGGUUGa---------------------------------------------- 953 0,1 ----------UGAUAUGUUUGAUAUUGGGUUGaa--------------------------------------------- 34 0,1 ----------UGAUAUGUUUGAUAUUGGGUUGau--------------------------------------------- 5 0,1 ----------UGAUAUGUUUGAUAUUGGGUUGg---------------------------------------------- 4 0,1 ----------UGAUAUGUUUGAUAUUGGGUUGU---------------------------------------------- 1321 0,2 ----------UGAUAUGUUUGAUAUUGGGUUGUa--------------------------------------------- 10 0,2 ----------UGAUAUGUUUGAUAUUGGGUUGUaa-------------------------------------------- 4 0,2 ----------UGAUAUGUUUGAUAUUGGGUUGUau-------------------------------------------- 2 0,2 ----------UGAUAUGUUUGAUAUUGGGUUGUU--------------------------------------------- 28 0,3 -----------GAUAUGUUUGAUAUUGGGUU------------------------------------------------ 10 1,0 -----------GAUAUGUUUGAUAUUGGGUUu----------------------------------------------- 5 1,0 -----------GAUAUGUUUGAUAUUGGGUUG----------------------------------------------- 45 1,1 -----------GAUAUGUUUGAUAUUGGGUUGa---------------------------------------------- 6 1,1 -----------GAUAUGUUUGAUAUUGGGUUGU---------------------------------------------- 9 1,2 -----------------------------------------------ACUAAAUGUCAAACAUAUUCU----------- 42 -----------------------------------------------ACUAAAUGUCAAACAUAUUCUU---------- 71 -----------------------------------------------ACUAAAUGUCAAACAUAUUCUUu--------- 2 -----------------------------------------------ACUAAAUGUCAAACAUAUUCUUA--------- 2 >hsa-mir-191 MA:16-38;mi:58-79 Tumor cggcuggacagcgggCAACGGAAUCCCAAAAGCAGCUGuugucuccagagcauuccaGCUGCGCUUGGAUUUCGUCCCCugcucuccugccu ---------------CAACGGAAUCCCAAAAGC----------------------------------------------------------- 1466 0,-5 ---------------CAACGGAAUCCCAAAAGCu---------------------------------------------------------- 2 0,-5 ---------------CAACGGAAUCCCAAAAGCA---------------------------------------------------------- 3385 0,-4 ---------------CAACGGAAUCCCAAAAGCAa--------------------------------------------------------- 522 0,-4 ---------------CAACGGAAUCCCAAAAGCAaa-------------------------------------------------------- 8 0,-4 ---------------CAACGGAAUCCCAAAAGCAu--------------------------------------------------------- 9 0,-4 ---------------CAACGGAAUCCCAAAAGCAG--------------------------------------------------------- 14432 0,-3 ---------------CAACGGAAUCCCAAAAGCAGa-------------------------------------------------------- 235 0,-3 ---------------CAACGGAAUCCCAAAAGCAGaa------------------------------------------------------- 27 0,-3 ---------------CAACGGAAUCCCAAAAGCAGau------------------------------------------------------- 250 0,-3 ---------------CAACGGAAUCCCAAAAGCAGu-------------------------------------------------------- 46 0,-3 ---------------CAACGGAAUCCCAAAAGCAGuu------------------------------------------------------- 157 0,-3 ---------------CAACGGAAUCCCAAAAGCAGC-------------------------------------------------------- 18339 0,-2 ---------------CAACGGAAUCCCAAAAGCAGCa------------------------------------------------------- 1241 0,-2 ---------------CAACGGAAUCCCAAAAGCAGCaa------------------------------------------------------ 65 0,-2 ---------------CAACGGAAUCCCAAAAGCAGCau------------------------------------------------------ 37 0,-2 ---------------CAACGGAAUCCCAAAAGCAGCc------------------------------------------------------- 283 0,-2 ---------------CAACGGAAUCCCAAAAGCAGCg------------------------------------------------------- 133 0,-2 ---------------CAACGGAAUCCCAAAAGCAGCU------------------------------------------------------- 127481 0,-1 ---------------CAACGGAAUCCCAAAAGCAGCUa------------------------------------------------------ 2352 0,-1 ---------------CAACGGAAUCCCAAAAGCAGCUaa----------------------------------------------------- 108 0,-1 ---------------CAACGGAAUCCCAAAAGCAGCUau----------------------------------------------------- 346 0,-1 ---------------CAACGGAAUCCCAAAAGCAGCUc------------------------------------------------------ 46 0,-1 ---------------CAACGGAAUCCCAAAAGCAGCUu------------------------------------------------------ 4459 0,-1 ---------------CAACGGAAUCCCAAAAGCAGCUuu----------------------------------------------------- 404 0,-1 ---------------CAACGGAAUCCCAAAAGCAGCUG------------------------------------------------------ 79777 0,0 ---------------CAACGGAAUCCCAAAAGCAGCUGa----------------------------------------------------- 2540 0,0 ---------------CAACGGAAUCCCAAAAGCAGCUGaa---------------------------------------------------- 91 0,0 ---------------CAACGGAAUCCCAAAAGCAGCUGau---------------------------------------------------- 14 0,0 ---------------CAACGGAAUCCCAAAAGCAGCUGc----------------------------------------------------- 185 0,0 ---------------CAACGGAAUCCCAAAAGCAGCUGg----------------------------------------------------- 180 0,0 ---------------CAACGGAAUCCCAAAAGCAGCUGU----------------------------------------------------- 20282 0,1 ---------------CAACGGAAUCCCAAAAGCAGCUGUa---------------------------------------------------- 149 0,1 ---------------CAACGGAAUCCCAAAAGCAGCUGUc---------------------------------------------------- 2 0,1 ---------------CAACGGAAUCCCAAAAGCAGCUGUU---------------------------------------------------- 712 0,2 ----------------AACGGAAUCCCAAAAGCA---------------------------------------------------------- 100 1,-4 ----------------AACGGAAUCCCAAAAGCAa--------------------------------------------------------- 10 1,-4 ----------------AACGGAAUCCCAAAAGCAG--------------------------------------------------------- 664 1,-3 ----------------AACGGAAUCCCAAAAGCAGa-------------------------------------------------------- 2 1,-3 ----------------AACGGAAUCCCAAAAGCAGau------------------------------------------------------- 8 1,-3 ----------------AACGGAAUCCCAAAAGCAGu-------------------------------------------------------- 2 1,-3 ----------------AACGGAAUCCCAAAAGCAGC-------------------------------------------------------- 907 1,-2 ----------------AACGGAAUCCCAAAAGCAGCa------------------------------------------------------- 24 1,-2 ----------------AACGGAAUCCCAAAAGCAGCc------------------------------------------------------- 4 1,-2 ----------------AACGGAAUCCCAAAAGCAGCg------------------------------------------------------- 2 1,-2 ----------------AACGGAAUCCCAAAAGCAGCU------------------------------------------------------- 6545 1,-1 ----------------AACGGAAUCCCAAAAGCAGCUa------------------------------------------------------ 111 1,-1 ----------------AACGGAAUCCCAAAAGCAGCUaa----------------------------------------------------- 3 1,-1 ----------------AACGGAAUCCCAAAAGCAGCUau----------------------------------------------------- 21 1,-1 ----------------AACGGAAUCCCAAAAGCAGCUu------------------------------------------------------ 225 1,-1 ----------------AACGGAAUCCCAAAAGCAGCUuu----------------------------------------------------- 19 1,-1 ----------------AACGGAAUCCCAAAAGCAGCUG------------------------------------------------------ 5777 1,0 ----------------AACGGAAUCCCAAAAGCAGCUGa----------------------------------------------------- 405 1,0 ----------------AACGGAAUCCCAAAAGCAGCUGaa---------------------------------------------------- 4 1,0 ----------------AACGGAAUCCCAAAAGCAGCUGc----------------------------------------------------- 2 1,0 ----------------AACGGAAUCCCAAAAGCAGCUGg----------------------------------------------------- 4 1,0 ----------------AACGGAAUCCCAAAAGCAGCUGU----------------------------------------------------- 2062 1,1 ----------------AACGGAAUCCCAAAAGCAGCUGUa---------------------------------------------------- 18 1,1 ----------------AACGGAAUCCCAAAAGCAGCUGUaa--------------------------------------------------- 2 1,1 ----------------AACGGAAUCCCAAAAGCAGCUGUU---------------------------------------------------- 68 1,2 ----------------AACGGAAUCCCAAAAGCAGCUGUUu--------------------------------------------------- 6 1,2 -----------------ACGGAAUCCCAAAAGCAG--------------------------------------------------------- 2 2,-3 -----------------ACGGAAUCCCAAAAGCAGC-------------------------------------------------------- 6 2,-2 -----------------ACGGAAUCCCAAAAGCAGCU------------------------------------------------------- 103 2,-1 -----------------ACGGAAUCCCAAAAGCAGCUa------------------------------------------------------ 2 2,-1 -----------------ACGGAAUCCCAAAAGCAGCUG------------------------------------------------------ 90 2,0 -----------------ACGGAAUCCCAAAAGCAGCUGa----------------------------------------------------- 2 2,0 -----------------ACGGAAUCCCAAAAGCAGCUGU----------------------------------------------------- 37 2,1 ---------------------------------------------------------GCUGCGCUUGGAUUUCGU----------------- 8 0,-4 ---------------------------------------------------------GCUGCGCUUGGAUUUCGUu---------------- 3 0,-4 ---------------------------------------------------------GCUGCGCUUGGAUUUCGUCuu-------------- 2 0,-3 ---------------------------------------------------------GCUGCGCUUGGAUUUCGUCC--------------- 19 0,-2 ---------------------------------------------------------GCUGCGCUUGGAUUUCGUCCC-------------- 24 0,-1 ---------------------------------------------------------GCUGCGCUUGGAUUUCGUCCCu------------- 2 0,-1 ---------------------------------------------------------GCUGCGCUUGGAUUUCGUCCCC------------- 11 0,0 ----------------------------------------------------------CUGCGCUUGGAUUUCGUCCC-------------- 2 1,-1 ----------------------------------------------------------CUGCGCUUGGAUUUCGUCCCC------------- 7 1,0 ----------------------------------------------------------CUGCGCUUGGAUUUCGUCCCCU------------ 2 1,1 >hsa-mir-1911 MA:12-34;mi:49-68 Tumor ucggcaucugcUGAGUACCGCCAUGUCUGUUGGGcauccacagucuccCACCAGGCAUUGUGGUCUCCgcugacgcuuug -----------UGAGUACCGCCAUGUCUGUUGG----------------------------------------------- 2 0,-1 -----------UGAGUACCGCCAUGUCUGUUGGG---------------------------------------------- 3 0,0 >hsa-mir-1912 3pM:46-67 Tumor cucuaggaugugcucauugcaugggcuguguauaguauuauucaaUACCCAGAGCAUGCAGUGUGAAcauaauagagauu ---------------------------------------------UACCCAGAGCAUGCAGUGUGAA------------- 2 0,0 >hsa-mir-192 MA:24-44;mi:67-88 Tumor gccgagaccgagugcacagggcuCUGACCUAUGAAUUGACAGCCagugcucucgucuccccucuggCUGCCAAUUCCAUAGGUCACAGguauguucgccucaaugccagc -----------------------CUGACCUAUGAAUUGACA--------------------------------------------------------------------- 58 0,-3 -----------------------CUGACCUAUGAAUUGACAG-------------------------------------------------------------------- 148 0,-2 -----------------------CUGACCUAUGAAUUGACAGa------------------------------------------------------------------- 18 0,-2 -----------------------CUGACCUAUGAAUUGACAGu------------------------------------------------------------------- 7 0,-2 -----------------------CUGACCUAUGAAUUGACAGC------------------------------------------------------------------- 1361 0,-1 -----------------------CUGACCUAUGAAUUGACAGCa------------------------------------------------------------------ 24 0,-1 -----------------------CUGACCUAUGAAUUGACAGCg------------------------------------------------------------------ 2 0,-1 -----------------------CUGACCUAUGAAUUGACAGCu------------------------------------------------------------------ 12 0,-1 -----------------------CUGACCUAUGAAUUGACAGCC------------------------------------------------------------------ 4093 0,0 -----------------------CUGACCUAUGAAUUGACAGCCc----------------------------------------------------------------- 14 0,0 -----------------------CUGACCUAUGAAUUGACAGCCu----------------------------------------------------------------- 99 0,0 -----------------------CUGACCUAUGAAUUGACAGCCuu---------------------------------------------------------------- 7 0,0 -----------------------CUGACCUAUGAAUUGACAGCCA----------------------------------------------------------------- 1426 0,1 -----------------------CUGACCUAUGAAUUGACAGCCAa---------------------------------------------------------------- 40 0,1 -----------------------CUGACCUAUGAAUUGACAGCCAaa--------------------------------------------------------------- 4 0,1 -----------------------CUGACCUAUGAAUUGACAGCCAu---------------------------------------------------------------- 443 0,1 -----------------------CUGACCUAUGAAUUGACAGCCAuu--------------------------------------------------------------- 101 0,1 -----------------------CUGACCUAUGAAUUGACAGCCAG---------------------------------------------------------------- 32 0,2 -----------------------CUGACCUAUGAAUUGACAGCCAGa--------------------------------------------------------------- 10 0,2 -----------------------CUGACCUAUGAAUUGACAGCCAGU--------------------------------------------------------------- 111 0,3 ------------------------UGACCUAUGAAUUGACAG-------------------------------------------------------------------- 5 1,-2 ------------------------UGACCUAUGAAUUGACAGC------------------------------------------------------------------- 112 1,-1 ------------------------UGACCUAUGAAUUGACAGCa------------------------------------------------------------------ 2 1,-1 ------------------------UGACCUAUGAAUUGACAGCC------------------------------------------------------------------ 491 1,0 ------------------------UGACCUAUGAAUUGACAGCCu----------------------------------------------------------------- 7 1,0 ------------------------UGACCUAUGAAUUGACAGCCA----------------------------------------------------------------- 615 1,1 ------------------------UGACCUAUGAAUUGACAGCCAa---------------------------------------------------------------- 47 1,1 ------------------------UGACCUAUGAAUUGACAGCCAaa--------------------------------------------------------------- 6 1,1 ------------------------UGACCUAUGAAUUGACAGCCAau--------------------------------------------------------------- 7 1,1 ------------------------UGACCUAUGAAUUGACAGCCAu---------------------------------------------------------------- 169 1,1 ------------------------UGACCUAUGAAUUGACAGCCAuu--------------------------------------------------------------- 29 1,1 ------------------------UGACCUAUGAAUUGACAGCCAG---------------------------------------------------------------- 711 1,2 ------------------------UGACCUAUGAAUUGACAGCCAGa--------------------------------------------------------------- 183 1,2 ------------------------UGACCUAUGAAUUGACAGCCAGaa-------------------------------------------------------------- 2 1,2 ------------------------UGACCUAUGAAUUGACAGCCAGc--------------------------------------------------------------- 2 1,2 ------------------------UGACCUAUGAAUUGACAGCCAGU--------------------------------------------------------------- 826 1,3 ------------------------UGACCUAUGAAUUGACAGCCAGUu-------------------------------------------------------------- 35 1,3 -------------------------GACCUAUGAAUUGACAGC------------------------------------------------------------------- 2 2,-1 -------------------------GACCUAUGAAUUGACAGCC------------------------------------------------------------------ 3 2,0 -------------------------GACCUAUGAAUUGACAGCCA----------------------------------------------------------------- 10 2,1 -------------------------GACCUAUGAAUUGACAGCCAG---------------------------------------------------------------- 20 2,2 -------------------------GACCUAUGAAUUGACAGCCAGU--------------------------------------------------------------- 14 2,3 ------------------------------------------------------------------CUGCCAAUUCCAUAGGUCACAG---------------------- 5 0,0 ------------------------------------------------------------------CUGCCAAUUCCAUAGGUCACAGa--------------------- 2 0,0 >hsa-mir-193a 5p:21-42;3p:55-76 Tumor cgaggaugggagcugagggcUGGGUCUUUGCGGGCGAGAUGAgggugucggaucAACUGGCCUACAAAGUCCCAGUucucggcccccg -------------------CUGGGUCUUUGCGGGCGAGAU------------------------------------------------ 2 -1,-2 -------------------CUGGGUCUUUGCGGGCGAGAUGA---------------------------------------------- 13 -1,0 --------------------UGGGUCUUUGCGGGCGAG-------------------------------------------------- 80 0,-4 --------------------UGGGUCUUUGCGGGCGAGu------------------------------------------------- 18 0,-4 --------------------UGGGUCUUUGCGGGCGAGuu------------------------------------------------ 2 0,-4 --------------------UGGGUCUUUGCGGGCGAGA------------------------------------------------- 255 0,-3 --------------------UGGGUCUUUGCGGGCGAGAa------------------------------------------------ 24 0,-3 --------------------UGGGUCUUUGCGGGCGAGAaa----------------------------------------------- 22 0,-3 --------------------UGGGUCUUUGCGGGCGAGAau----------------------------------------------- 12 0,-3 --------------------UGGGUCUUUGCGGGCGAGAU------------------------------------------------ 1218 0,-2 --------------------UGGGUCUUUGCGGGCGAGAUa----------------------------------------------- 79 0,-2 --------------------UGGGUCUUUGCGGGCGAGAUaa---------------------------------------------- 27 0,-2 --------------------UGGGUCUUUGCGGGCGAGAUau---------------------------------------------- 5 0,-2 --------------------UGGGUCUUUGCGGGCGAGAUu----------------------------------------------- 378 0,-2 --------------------UGGGUCUUUGCGGGCGAGAUuu---------------------------------------------- 11 0,-2 --------------------UGGGUCUUUGCGGGCGAGAUG----------------------------------------------- 874 0,-1 --------------------UGGGUCUUUGCGGGCGAGAUGc---------------------------------------------- 59 0,-1 --------------------UGGGUCUUUGCGGGCGAGAUGg---------------------------------------------- 5 0,-1 --------------------UGGGUCUUUGCGGGCGAGAUGu---------------------------------------------- 324 0,-1 --------------------UGGGUCUUUGCGGGCGAGAUGuu--------------------------------------------- 29 0,-1 --------------------UGGGUCUUUGCGGGCGAGAUGA---------------------------------------------- 6885 0,0 --------------------UGGGUCUUUGCGGGCGAGAUGAa--------------------------------------------- 344 0,0 --------------------UGGGUCUUUGCGGGCGAGAUGAaa-------------------------------------------- 29 0,0 --------------------UGGGUCUUUGCGGGCGAGAUGAau-------------------------------------------- 21 0,0 --------------------UGGGUCUUUGCGGGCGAGAUGAc--------------------------------------------- 2 0,0 --------------------UGGGUCUUUGCGGGCGAGAUGAu--------------------------------------------- 446 0,0 --------------------UGGGUCUUUGCGGGCGAGAUGAuu-------------------------------------------- 25 0,0 --------------------UGGGUCUUUGCGGGCGAGAUGAG--------------------------------------------- 2 0,1 --------------------UGGGUCUUUGCGGGCGAGAUGAGu-------------------------------------------- 2 0,1 ---------------------GGGUCUUUGCGGGCGAGA------------------------------------------------- 2 1,-3 ---------------------GGGUCUUUGCGGGCGAGAU------------------------------------------------ 22 1,-2 ---------------------GGGUCUUUGCGGGCGAGAUu----------------------------------------------- 5 1,-2 ---------------------GGGUCUUUGCGGGCGAGAUG----------------------------------------------- 11 1,-1 ---------------------GGGUCUUUGCGGGCGAGAUGu---------------------------------------------- 6 1,-1 ---------------------GGGUCUUUGCGGGCGAGAUGA---------------------------------------------- 184 1,0 ---------------------GGGUCUUUGCGGGCGAGAUGAa--------------------------------------------- 6 1,0 ---------------------GGGUCUUUGCGGGCGAGAUGAaa-------------------------------------------- 2 1,0 ---------------------GGGUCUUUGCGGGCGAGAUGAau-------------------------------------------- 2 1,0 ---------------------GGGUCUUUGCGGGCGAGAUGAu--------------------------------------------- 10 1,0 -----------------------------------------------------CAACUGGCCUACAAAGUCCCAGU------------ 7 -1,0 ------------------------------------------------------AACUGGCCUACAAAGUCC---------------- 574 0,-4 ------------------------------------------------------AACUGGCCUACAAAGUCCa--------------- 2 0,-4 ------------------------------------------------------AACUGGCCUACAAAGUCCaa-------------- 2 0,-4 ------------------------------------------------------AACUGGCCUACAAAGUCCu--------------- 2 0,-4 ------------------------------------------------------AACUGGCCUACAAAGUCCC--------------- 755 0,-3 ------------------------------------------------------AACUGGCCUACAAAGUCCCc-------------- 7 0,-3 ------------------------------------------------------AACUGGCCUACAAAGUCCCu-------------- 19 0,-3 ------------------------------------------------------AACUGGCCUACAAAGUCCCuu------------- 4 0,-3 ------------------------------------------------------AACUGGCCUACAAAGUCCCA-------------- 2178 0,-2 ------------------------------------------------------AACUGGCCUACAAAGUCCCAa------------- 320 0,-2 ------------------------------------------------------AACUGGCCUACAAAGUCCCAaa------------ 132 0,-2 ------------------------------------------------------AACUGGCCUACAAAGUCCCAau------------ 281 0,-2 ------------------------------------------------------AACUGGCCUACAAAGUCCCAc------------- 3 0,-2 ------------------------------------------------------AACUGGCCUACAAAGUCCCAu------------- 585 0,-2 ------------------------------------------------------AACUGGCCUACAAAGUCCCAuu------------ 489 0,-2 ------------------------------------------------------AACUGGCCUACAAAGUCCCAG------------- 4529 0,-1 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGa------------ 1348 0,-1 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGaa----------- 26 0,-1 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGau----------- 15 0,-1 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGc------------ 195 0,-1 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGg------------ 62 0,-1 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGU------------ 35143 0,0 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGUa----------- 267 0,0 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGUaa---------- 26 0,0 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGUau---------- 21 0,0 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGUc----------- 4 0,0 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGUg----------- 8 0,0 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGUU----------- 954 0,1 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGUUa---------- 2 0,1 ------------------------------------------------------AACUGGCCUACAAAGUCCCAGUUu---------- 5 0,1 -------------------------------------------------------ACUGGCCUACAAAGUCCC--------------- 6 1,-3 -------------------------------------------------------ACUGGCCUACAAAGUCCCA-------------- 38 1,-2 -------------------------------------------------------ACUGGCCUACAAAGUCCCAa------------- 5 1,-2 -------------------------------------------------------ACUGGCCUACAAAGUCCCAu------------- 4 1,-2 -------------------------------------------------------ACUGGCCUACAAAGUCCCAuu------------ 2 1,-2 -------------------------------------------------------ACUGGCCUACAAAGUCCCAG------------- 101 1,-1 -------------------------------------------------------ACUGGCCUACAAAGUCCCAGa------------ 22 1,-1 -------------------------------------------------------ACUGGCCUACAAAGUCCCAGU------------ 512 1,0 -------------------------------------------------------ACUGGCCUACAAAGUCCCAGUa----------- 4 1,0 -------------------------------------------------------ACUGGCCUACAAAGUCCCAGUU----------- 11 1,1 --------------------------------------------------------CUGGCCUACAAAGUCCCAGU------------ 2 2,0 >hsa-mir-193b mi:14-35;MA:51-72 Tumor guggucucagaauCGGGGUUUUGAGGGCGAGAUGAguuuauguuuuauccAACUGGCCCUCAAAGUCCCGCUuuuggggucau ------------UCGGGGUUUUGAGGGCGAGAU-------------------------------------------------- 4 -1,-2 -------------CGGGGUUUUGAGGGCGAGA--------------------------------------------------- 6 0,-3 -------------CGGGGUUUUGAGGGCGAGAU-------------------------------------------------- 49 0,-2 -------------CGGGGUUUUGAGGGCGAGAUa------------------------------------------------- 4 0,-2 -------------CGGGGUUUUGAGGGCGAGAUu------------------------------------------------- 6 0,-2 -------------CGGGGUUUUGAGGGCGAGAUG------------------------------------------------- 73 0,-1 -------------CGGGGUUUUGAGGGCGAGAUGc------------------------------------------------ 2 0,-1 -------------CGGGGUUUUGAGGGCGAGAUGu------------------------------------------------ 28 0,-1 -------------CGGGGUUUUGAGGGCGAGAUGA------------------------------------------------ 642 0,0 -------------CGGGGUUUUGAGGGCGAGAUGAa----------------------------------------------- 10 0,0 -------------CGGGGUUUUGAGGGCGAGAUGAu----------------------------------------------- 5 0,0 --------------GGGGUUUUGAGGGCGAGAUGA------------------------------------------------ 9 1,0 -------------------------------------------------CAACUGGCCCUCAAAGUCCCGCU----------- 5 -1,0 --------------------------------------------------AACUGGCCCUCAAAGUCC--------------- 103 0,-4 --------------------------------------------------AACUGGCCCUCAAAGUCCC-------------- 149 0,-3 --------------------------------------------------AACUGGCCCUCAAAGUCCCa------------- 3 0,-3 --------------------------------------------------AACUGGCCCUCAAAGUCCCc------------- 2 0,-3 --------------------------------------------------AACUGGCCCUCAAAGUCCCu------------- 6 0,-3 --------------------------------------------------AACUGGCCCUCAAAGUCCCG------------- 2308 0,-2 --------------------------------------------------AACUGGCCCUCAAAGUCCCGa------------ 304 0,-2 --------------------------------------------------AACUGGCCCUCAAAGUCCCGaa----------- 10 0,-2 --------------------------------------------------AACUGGCCCUCAAAGUCCCGau----------- 38 0,-2 --------------------------------------------------AACUGGCCCUCAAAGUCCCGu------------ 744 0,-2 --------------------------------------------------AACUGGCCCUCAAAGUCCCGuu----------- 171 0,-2 --------------------------------------------------AACUGGCCCUCAAAGUCCCGC------------ 3932 0,-1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCa----------- 520 0,-1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCaa---------- 106 0,-1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCau---------- 190 0,-1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCc----------- 441 0,-1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCg----------- 20 0,-1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCU----------- 23588 0,0 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUa---------- 740 0,0 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUaa--------- 36 0,0 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUau--------- 292 0,0 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUc---------- 6 0,0 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUg---------- 40 0,0 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUU---------- 3442 0,1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUUa--------- 24 0,1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUUc--------- 2 0,1 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUUU--------- 1030 0,2 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUUUa-------- 2 0,2 --------------------------------------------------AACUGGCCCUCAAAGUCCCGCUUUU-------- 170 0,3 ---------------------------------------------------ACUGGCCCUCAAAGUCCC-------------- 2 1,-3 ---------------------------------------------------ACUGGCCCUCAAAGUCCCG------------- 92 1,-2 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGa------------ 10 1,-2 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGu------------ 16 1,-2 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGuu----------- 5 1,-2 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGC------------ 126 1,-1 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCa----------- 2 1,-1 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCaa---------- 2 1,-1 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCau---------- 2 1,-1 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCc----------- 2 1,-1 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCU----------- 1101 1,0 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCUa---------- 93 1,0 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCUaa--------- 7 1,0 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCUau--------- 93 1,0 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCUc---------- 2 1,0 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCUU---------- 383 1,1 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCUUa--------- 2 1,1 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCUUU--------- 163 1,2 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCUUUU-------- 23 1,3 ---------------------------------------------------ACUGGCCCUCAAAGUCCCGCUUUUu------- 2 1,3 ----------------------------------------------------CUGGCCCUCAAAGUCCCGCU----------- 20 2,0 >hsa-mir-194-1 5pM:15-36 Tumor augguguuaucaagUGUAACAGCAACUCCAUGUGGAcuguguaccaauuuccaguggagaugcuguuacuuuugaugguuaccaa --------------UGUAACAGCAACUCCAUG----------------------------------------------------- 6 0,-4 --------------UGUAACAGCAACUCCAUGU---------------------------------------------------- 12 0,-3 --------------UGUAACAGCAACUCCAUGUG--------------------------------------------------- 20 0,-2 --------------UGUAACAGCAACUCCAUGUGa-------------------------------------------------- 29 0,-2 --------------UGUAACAGCAACUCCAUGUGaa------------------------------------------------- 7 0,-2 --------------UGUAACAGCAACUCCAUGUGu-------------------------------------------------- 21 0,-2 --------------UGUAACAGCAACUCCAUGUGG-------------------------------------------------- 1017 0,-1 --------------UGUAACAGCAACUCCAUGUGGc------------------------------------------------- 3 0,-1 --------------UGUAACAGCAACUCCAUGUGGu------------------------------------------------- 8 0,-1 --------------UGUAACAGCAACUCCAUGUGGA------------------------------------------------- 4018 0,0 --------------UGUAACAGCAACUCCAUGUGGAu------------------------------------------------ 89 0,0 --------------UGUAACAGCAACUCCAUGUGGAC------------------------------------------------ 20 0,1 --------------UGUAACAGCAACUCCAUGUGGACa----------------------------------------------- 2 0,1 ---------------GUAACAGCAACUCCAUGUGG-------------------------------------------------- 24 1,-1 ---------------GUAACAGCAACUCCAUGUGGA------------------------------------------------- 120 1,0 >hsa-mir-194-2 MA:15-36;mi:51-72 Tumor ugguucccgcccccUGUAACAGCAACUCCAUGUGGAagugcccacugguuCCAGUGGGGCUGCUGUUAUCUGgggcgagggccag -------------CUGUAACAGCAACUCCAUGUGGA------------------------------------------------- 10 -1,0 --------------UGUAACAGCAACUCCAUG----------------------------------------------------- 6 0,-4 --------------UGUAACAGCAACUCCAUGU---------------------------------------------------- 12 0,-3 --------------UGUAACAGCAACUCCAUGUG--------------------------------------------------- 20 0,-2 --------------UGUAACAGCAACUCCAUGUGa-------------------------------------------------- 29 0,-2 --------------UGUAACAGCAACUCCAUGUGaa------------------------------------------------- 7 0,-2 --------------UGUAACAGCAACUCCAUGUGu-------------------------------------------------- 21 0,-2 --------------UGUAACAGCAACUCCAUGUGG-------------------------------------------------- 1017 0,-1 --------------UGUAACAGCAACUCCAUGUGGc------------------------------------------------- 3 0,-1 --------------UGUAACAGCAACUCCAUGUGGu------------------------------------------------- 8 0,-1 --------------UGUAACAGCAACUCCAUGUGGA------------------------------------------------- 4018 0,0 --------------UGUAACAGCAACUCCAUGUGGAu------------------------------------------------ 89 0,0 --------------UGUAACAGCAACUCCAUGUGGAA------------------------------------------------ 1759 0,1 --------------UGUAACAGCAACUCCAUGUGGAAa----------------------------------------------- 106 0,1 --------------UGUAACAGCAACUCCAUGUGGAAaa---------------------------------------------- 2 0,1 --------------UGUAACAGCAACUCCAUGUGGAAu----------------------------------------------- 173 0,1 --------------UGUAACAGCAACUCCAUGUGGAAG----------------------------------------------- 6 0,2 ---------------GUAACAGCAACUCCAUGUGG-------------------------------------------------- 24 1,-1 ---------------GUAACAGCAACUCCAUGUGGA------------------------------------------------- 120 1,0 ---------------GUAACAGCAACUCCAUGUGGAA------------------------------------------------ 45 1,1 >hsa-mir-195 MA:15-35;mi:53-74 Tumor agcuucccuggcucUAGCAGCACAGAAAUAUUGGCacagggaagcgagucugCCAAUAUUGGCUGUGCUGCUCCaggcaggguggug -------------CUAGCAGCACAGAAAUAUUGG----------------------------------------------------- 5 -1,-1 -------------CUAGCAGCACAGAAAUAUUGGC---------------------------------------------------- 17 -1,0 -------------CUAGCAGCACAGAAAUAUUGGCA--------------------------------------------------- 53 -1,1 -------------CUAGCAGCACAGAAAUAUUGGCAa-------------------------------------------------- 2 -1,1 -------------CUAGCAGCACAGAAAUAUUGGCAu-------------------------------------------------- 2 -1,1 --------------UAGCAGCACAGAAAUAUU------------------------------------------------------- 80 0,-3 --------------UAGCAGCACAGAAAUAUUG------------------------------------------------------ 169 0,-2 --------------UAGCAGCACAGAAAUAUUGa----------------------------------------------------- 48 0,-2 --------------UAGCAGCACAGAAAUAUUGu----------------------------------------------------- 9 0,-2 --------------UAGCAGCACAGAAAUAUUGG----------------------------------------------------- 1661 0,-1 --------------UAGCAGCACAGAAAUAUUGGa---------------------------------------------------- 372 0,-1 --------------UAGCAGCACAGAAAUAUUGGaa--------------------------------------------------- 99 0,-1 --------------UAGCAGCACAGAAAUAUUGGu---------------------------------------------------- 30 0,-1 --------------UAGCAGCACAGAAAUAUUGGC---------------------------------------------------- 4317 0,0 --------------UAGCAGCACAGAAAUAUUGGCc--------------------------------------------------- 62 0,0 --------------UAGCAGCACAGAAAUAUUGGCg--------------------------------------------------- 38 0,0 --------------UAGCAGCACAGAAAUAUUGGCu--------------------------------------------------- 103 0,0 --------------UAGCAGCACAGAAAUAUUGGCA--------------------------------------------------- 11312 0,1 --------------UAGCAGCACAGAAAUAUUGGCAa-------------------------------------------------- 2207 0,1 --------------UAGCAGCACAGAAAUAUUGGCAaa------------------------------------------------- 25 0,1 --------------UAGCAGCACAGAAAUAUUGGCAau------------------------------------------------- 41 0,1 --------------UAGCAGCACAGAAAUAUUGGCAg-------------------------------------------------- 24 0,1 --------------UAGCAGCACAGAAAUAUUGGCAu-------------------------------------------------- 1305 0,1 --------------UAGCAGCACAGAAAUAUUGGCAuu------------------------------------------------- 31 0,1 --------------UAGCAGCACAGAAAUAUUGGCAC-------------------------------------------------- 6 0,2 ---------------AGCAGCACAGAAAUAUUG------------------------------------------------------ 4 1,-2 ---------------AGCAGCACAGAAAUAUUGG----------------------------------------------------- 31 1,-1 ---------------AGCAGCACAGAAAUAUUGGC---------------------------------------------------- 152 1,0 ---------------AGCAGCACAGAAAUAUUGGCc--------------------------------------------------- 2 1,0 ---------------AGCAGCACAGAAAUAUUGGCA--------------------------------------------------- 501 1,1 ---------------AGCAGCACAGAAAUAUUGGCAa-------------------------------------------------- 72 1,1 ---------------AGCAGCACAGAAAUAUUGGCAu-------------------------------------------------- 53 1,1 ----------------GCAGCACAGAAAUAUUGG----------------------------------------------------- 2 2,-1 ----------------GCAGCACAGAAAUAUUGGCA--------------------------------------------------- 19 2,1 ----------------------------------------------------CCAAUAUUGGCUGUGCUGCU--------------- 2 0,-2 ----------------------------------------------------CCAAUAUUGGCUGUGCUGCUC-------------- 6 0,-1 ----------------------------------------------------CCAAUAUUGGCUGUGCUGCUCCA------------ 6 0,1 ----------------------------------------------------CCAAUAUUGGCUGUGCUGCUCCAa----------- 2 0,1 ----------------------------------------------------CCAAUAUUGGCUGUGCUGCUCCAu----------- 2 0,1 >hsa-mir-196a-1 5pM:7-28 Tumor gugaauUAGGUAGUUUCAUGUUGUUGGGccuggguuucugaacacaacaacauuaaaccacccgauucac -----UUAGGUAGUUUCAUGUUGUUGGG------------------------------------------ 2 -1,0 ------UAGGUAGUUUCAUGUUGU---------------------------------------------- 34 0,-4 ------UAGGUAGUUUCAUGUUGUU--------------------------------------------- 841 0,-3 ------UAGGUAGUUUCAUGUUGUUa-------------------------------------------- 20 0,-3 ------UAGGUAGUUUCAUGUUGUUu-------------------------------------------- 18 0,-3 ------UAGGUAGUUUCAUGUUGUUG-------------------------------------------- 1143 0,-2 ------UAGGUAGUUUCAUGUUGUUGa------------------------------------------- 134 0,-2 ------UAGGUAGUUUCAUGUUGUUGaa------------------------------------------ 10 0,-2 ------UAGGUAGUUUCAUGUUGUUGu------------------------------------------- 155 0,-2 ------UAGGUAGUUUCAUGUUGUUGuu------------------------------------------ 12 0,-2 ------UAGGUAGUUUCAUGUUGUUGG------------------------------------------- 7277 0,-1 ------UAGGUAGUUUCAUGUUGUUGGa------------------------------------------ 2269 0,-1 ------UAGGUAGUUUCAUGUUGUUGGaa----------------------------------------- 370 0,-1 ------UAGGUAGUUUCAUGUUGUUGGau----------------------------------------- 33 0,-1 ------UAGGUAGUUUCAUGUUGUUGGu------------------------------------------ 471 0,-1 ------UAGGUAGUUUCAUGUUGUUGGuu----------------------------------------- 14 0,-1 ------UAGGUAGUUUCAUGUUGUUGGG------------------------------------------ 10594 0,0 ------UAGGUAGUUUCAUGUUGUUGGGg----------------------------------------- 5 0,0 ------UAGGUAGUUUCAUGUUGUUGGGu----------------------------------------- 2328 0,0 ------UAGGUAGUUUCAUGUUGUUGGGuu---------------------------------------- 106 0,0 ------UAGGUAGUUUCAUGUUGUUGGGC----------------------------------------- 29 0,1 -------AGGUAGUUUCAUGUUGUU--------------------------------------------- 27 1,-3 -------AGGUAGUUUCAUGUUGUUG-------------------------------------------- 38 1,-2 -------AGGUAGUUUCAUGUUGUUGa------------------------------------------- 6 1,-2 -------AGGUAGUUUCAUGUUGUUGu------------------------------------------- 11 1,-2 -------AGGUAGUUUCAUGUUGUUGG------------------------------------------- 336 1,-1 -------AGGUAGUUUCAUGUUGUUGGa------------------------------------------ 95 1,-1 -------AGGUAGUUUCAUGUUGUUGGaa----------------------------------------- 6 1,-1 -------AGGUAGUUUCAUGUUGUUGGu------------------------------------------ 9 1,-1 -------AGGUAGUUUCAUGUUGUUGGuu----------------------------------------- 2 1,-1 -------AGGUAGUUUCAUGUUGUUGGG------------------------------------------ 487 1,0 -------AGGUAGUUUCAUGUUGUUGGGu----------------------------------------- 121 1,0 -------AGGUAGUUUCAUGUUGUUGGGuu---------------------------------------- 3 1,0 --------GGUAGUUUCAUGUUGUUGG------------------------------------------- 16 2,-1 --------GGUAGUUUCAUGUUGUUGGG------------------------------------------ 12 2,0 --------GGUAGUUUCAUGUUGUUGGGu----------------------------------------- 3 2,0 >hsa-mir-196a-2 MA:25-46;mi:62-83 Tumor ugcucgcucagcugaucuguggcuUAGGUAGUUUCAUGUUGUUGGGauugaguuuugaacuCGGCAACAAGAAACUGCCUGAGuuacaucagucgguuuucgucgagggc -----------------------UUAGGUAGUUUCAUGUUGUUGGG---------------------------------------------------------------- 2 -1,0 ------------------------UAGGUAGUUUCAUGUUGU-------------------------------------------------------------------- 34 0,-4 ------------------------UAGGUAGUUUCAUGUUGUU------------------------------------------------------------------- 841 0,-3 ------------------------UAGGUAGUUUCAUGUUGUUa------------------------------------------------------------------ 20 0,-3 ------------------------UAGGUAGUUUCAUGUUGUUu------------------------------------------------------------------ 18 0,-3 ------------------------UAGGUAGUUUCAUGUUGUUG------------------------------------------------------------------ 1143 0,-2 ------------------------UAGGUAGUUUCAUGUUGUUGa----------------------------------------------------------------- 134 0,-2 ------------------------UAGGUAGUUUCAUGUUGUUGaa---------------------------------------------------------------- 10 0,-2 ------------------------UAGGUAGUUUCAUGUUGUUGu----------------------------------------------------------------- 155 0,-2 ------------------------UAGGUAGUUUCAUGUUGUUGuu---------------------------------------------------------------- 12 0,-2 ------------------------UAGGUAGUUUCAUGUUGUUGG----------------------------------------------------------------- 7277 0,-1 ------------------------UAGGUAGUUUCAUGUUGUUGGa---------------------------------------------------------------- 2269 0,-1 ------------------------UAGGUAGUUUCAUGUUGUUGGaa--------------------------------------------------------------- 370 0,-1 ------------------------UAGGUAGUUUCAUGUUGUUGGau--------------------------------------------------------------- 33 0,-1 ------------------------UAGGUAGUUUCAUGUUGUUGGu---------------------------------------------------------------- 471 0,-1 ------------------------UAGGUAGUUUCAUGUUGUUGGuu--------------------------------------------------------------- 14 0,-1 ------------------------UAGGUAGUUUCAUGUUGUUGGG---------------------------------------------------------------- 10594 0,0 ------------------------UAGGUAGUUUCAUGUUGUUGGGg--------------------------------------------------------------- 5 0,0 ------------------------UAGGUAGUUUCAUGUUGUUGGGu--------------------------------------------------------------- 2328 0,0 ------------------------UAGGUAGUUUCAUGUUGUUGGGuu-------------------------------------------------------------- 106 0,0 ------------------------UAGGUAGUUUCAUGUUGUUGGGA--------------------------------------------------------------- 5702 0,1 ------------------------UAGGUAGUUUCAUGUUGUUGGGAa-------------------------------------------------------------- 347 0,1 ------------------------UAGGUAGUUUCAUGUUGUUGGGAaa------------------------------------------------------------- 23 0,1 ------------------------UAGGUAGUUUCAUGUUGUUGGGAau------------------------------------------------------------- 17 0,1 ------------------------UAGGUAGUUUCAUGUUGUUGGGAc-------------------------------------------------------------- 4 0,1 ------------------------UAGGUAGUUUCAUGUUGUUGGGAg-------------------------------------------------------------- 7 0,1 ------------------------UAGGUAGUUUCAUGUUGUUGGGAU-------------------------------------------------------------- 296 0,2 ------------------------UAGGUAGUUUCAUGUUGUUGGGAUU------------------------------------------------------------- 2 0,3 -------------------------AGGUAGUUUCAUGUUGUU------------------------------------------------------------------- 27 1,-3 -------------------------AGGUAGUUUCAUGUUGUUG------------------------------------------------------------------ 38 1,-2 -------------------------AGGUAGUUUCAUGUUGUUGa----------------------------------------------------------------- 6 1,-2 -------------------------AGGUAGUUUCAUGUUGUUGu----------------------------------------------------------------- 11 1,-2 -------------------------AGGUAGUUUCAUGUUGUUGG----------------------------------------------------------------- 336 1,-1 -------------------------AGGUAGUUUCAUGUUGUUGGa---------------------------------------------------------------- 95 1,-1 -------------------------AGGUAGUUUCAUGUUGUUGGaa--------------------------------------------------------------- 6 1,-1 -------------------------AGGUAGUUUCAUGUUGUUGGu---------------------------------------------------------------- 9 1,-1 -------------------------AGGUAGUUUCAUGUUGUUGGuu--------------------------------------------------------------- 2 1,-1 -------------------------AGGUAGUUUCAUGUUGUUGGG---------------------------------------------------------------- 487 1,0 -------------------------AGGUAGUUUCAUGUUGUUGGGu--------------------------------------------------------------- 121 1,0 -------------------------AGGUAGUUUCAUGUUGUUGGGuu-------------------------------------------------------------- 3 1,0 -------------------------AGGUAGUUUCAUGUUGUUGGGA--------------------------------------------------------------- 270 1,1 -------------------------AGGUAGUUUCAUGUUGUUGGGAa-------------------------------------------------------------- 18 1,1 -------------------------AGGUAGUUUCAUGUUGUUGGGAU-------------------------------------------------------------- 14 1,2 --------------------------GGUAGUUUCAUGUUGUUGG----------------------------------------------------------------- 16 2,-1 --------------------------GGUAGUUUCAUGUUGUUGGG---------------------------------------------------------------- 12 2,0 --------------------------GGUAGUUUCAUGUUGUUGGGu--------------------------------------------------------------- 3 2,0 --------------------------GGUAGUUUCAUGUUGUUGGGA--------------------------------------------------------------- 12 2,1 --------------------------GGUAGUUUCAUGUUGUUGGGAa-------------------------------------------------------------- 2 2,1 ------------------------------------------------------------UCGGCAACAAGAAACUGCCU------------------------------ 2 -1,-3 ------------------------------------------------------------UCGGCAACAAGAAACUGCCUaa---------------------------- 2 -1,-3 ------------------------------------------------------------UCGGCAACAAGAAACUGCCUGu---------------------------- 5 -1,-2 ------------------------------------------------------------UCGGCAACAAGAAACUGCCUGA---------------------------- 468 -1,-1 ------------------------------------------------------------UCGGCAACAAGAAACUGCCUGAa--------------------------- 5 -1,-1 ------------------------------------------------------------UCGGCAACAAGAAACUGCCUGAu--------------------------- 3 -1,-1 ------------------------------------------------------------UCGGCAACAAGAAACUGCCUGAG--------------------------- 189 -1,0 ------------------------------------------------------------UCGGCAACAAGAAACUGCCUGAGa-------------------------- 11 -1,0 ------------------------------------------------------------UCGGCAACAAGAAACUGCCUGAGU-------------------------- 53 -1,1 -------------------------------------------------------------CGGCAACAAGAAACUGCCUGA---------------------------- 27 0,-1 -------------------------------------------------------------CGGCAACAAGAAACUGCCUGAG--------------------------- 78 0,0 --------------------------------------------------------------GGCAACAAGAAACUGCCUGAG--------------------------- 2 1,0 >hsa-mir-196b MA:15-36;mi:50-71 Tumor acuggucggugauuUAGGUAGUUUCCUGUUGUUGGGauccaccuuucucUCGACAGCACGACACUGCCUUCauuacuucaguug --------------UAGGUAGUUUCCUGUUGU---------------------------------------------------- 4 0,-4 --------------UAGGUAGUUUCCUGUUGUU--------------------------------------------------- 40 0,-3 --------------UAGGUAGUUUCCUGUUGUUG-------------------------------------------------- 108 0,-2 --------------UAGGUAGUUUCCUGUUGUUGa------------------------------------------------- 2 0,-2 --------------UAGGUAGUUUCCUGUUGUUGG------------------------------------------------- 532 0,-1 --------------UAGGUAGUUUCCUGUUGUUGGa------------------------------------------------ 346 0,-1 --------------UAGGUAGUUUCCUGUUGUUGGaa----------------------------------------------- 28 0,-1 --------------UAGGUAGUUUCCUGUUGUUGGau----------------------------------------------- 2 0,-1 --------------UAGGUAGUUUCCUGUUGUUGGu------------------------------------------------ 35 0,-1 --------------UAGGUAGUUUCCUGUUGUUGGG------------------------------------------------ 914 0,0 --------------UAGGUAGUUUCCUGUUGUUGGGu----------------------------------------------- 224 0,0 --------------UAGGUAGUUUCCUGUUGUUGGGuu---------------------------------------------- 5 0,0 --------------UAGGUAGUUUCCUGUUGUUGGGA----------------------------------------------- 671 0,1 --------------UAGGUAGUUUCCUGUUGUUGGGAa---------------------------------------------- 27 0,1 --------------UAGGUAGUUUCCUGUUGUUGGGAU---------------------------------------------- 17 0,2 ---------------AGGUAGUUUCCUGUUGUU--------------------------------------------------- 2 1,-3 ---------------AGGUAGUUUCCUGUUGUUGG------------------------------------------------- 12 1,-1 ---------------AGGUAGUUUCCUGUUGUUGGa------------------------------------------------ 5 1,-1 ---------------AGGUAGUUUCCUGUUGUUGGG------------------------------------------------ 16 1,0 ---------------AGGUAGUUUCCUGUUGUUGGGu----------------------------------------------- 6 1,0 ---------------AGGUAGUUUCCUGUUGUUGGGA----------------------------------------------- 4 1,1 -------------------------------------------------UCGACAGCACGACACUGCCUUC------------- 4 0,0 -------------------------------------------------UCGACAGCACGACACUGCCUUCA------------ 6 0,1 >hsa-mir-197 3pM:48-69 Tumor ggcugugccggguagagagggcagugggagguaagagcucuucacccUUCACCACCUUCUCCACCCAGCauggcc ----------------------------------------------CUUCACCACCUUCUCCACCCAGC------ 15 -1,0 ----------------------------------------------CUUCACCACCUUCUCCACCCAGCu----- 2 -1,0 -----------------------------------------------UUCACCACCUUCUCCACC---------- 4 0,-4 -----------------------------------------------UUCACCACCUUCUCCACCC--------- 136 0,-3 -----------------------------------------------UUCACCACCUUCUCCACCCA-------- 37 0,-2 -----------------------------------------------UUCACCACCUUCUCCACCCAa------- 4 0,-2 -----------------------------------------------UUCACCACCUUCUCCACCCAu------- 11 0,-2 -----------------------------------------------UUCACCACCUUCUCCACCCAG------- 653 0,-1 -----------------------------------------------UUCACCACCUUCUCCACCCAGa------ 331 0,-1 -----------------------------------------------UUCACCACCUUCUCCACCCAGaa----- 16 0,-1 -----------------------------------------------UUCACCACCUUCUCCACCCAGu------ 342 0,-1 -----------------------------------------------UUCACCACCUUCUCCACCCAGuu----- 4 0,-1 -----------------------------------------------UUCACCACCUUCUCCACCCAGC------ 5408 0,0 -----------------------------------------------UUCACCACCUUCUCCACCCAGCg----- 2 0,0 -----------------------------------------------UUCACCACCUUCUCCACCCAGCu----- 74 0,0 -----------------------------------------------UUCACCACCUUCUCCACCCAGCuu---- 2 0,0 -----------------------------------------------UUCACCACCUUCUCCACCCAGCA----- 206 0,1 -----------------------------------------------UUCACCACCUUCUCCACCCAGCAa---- 15 0,1 -----------------------------------------------UUCACCACCUUCUCCACCCAGCAU---- 6 0,2 ------------------------------------------------UCACCACCUUCUCCACCCAG------- 6 1,-1 ------------------------------------------------UCACCACCUUCUCCACCCAGC------ 81 1,0 ------------------------------------------------UCACCACCUUCUCCACCCAGCA----- 4 1,1 ------------------------------------------------UCACCACCUUCUCCACCCAGCAUu--- 2 1,2 -------------------------------------------------CACCACCUUCUCCACCCAGC------ 3 2,0 >hsa-mir-1973 3pM:26-44 Tumor uauguucaacggccaugguauccugACCGUGCAAAGGUAGCAUA -------------------------ACCGUGCAAAGGUAGCAUA 4 0,0 >hsa-mir-1976 3pM:33-52 Tumor gcagcaaggaaggcagggguccuaagguguguCCUCCUGCCCUCCUUGCUGU --------------------------------CCUCCUGCCCUCCUUGCUGU 6 0,0 ---------------------------------CUCCUGCCCUCCUUGCUGU 4 1,0 ----------------------------------UCCUGCCCUCCUUGCUGU 6 2,0 >hsa-mir-199a-1 5p:6-28;3p:47-68 Tumor gccaaCCCAGUGUUCAGACUACCUGUUCaggaggcucucaauguguACAGUAGUCUGCACAUUGGUUAggc ----ACCCAGUGUUCAGACUACCUGUU-------------------------------------------- 8 -1,-1 ----ACCCAGUGUUCAGACUACCUGUUC------------------------------------------- 8 -1,0 -----CCCAGUGUUCAGACUACC------------------------------------------------ 490 0,-5 -----CCCAGUGUUCAGACUACCg----------------------------------------------- 2 0,-5 -----CCCAGUGUUCAGACUACCU----------------------------------------------- 1363 0,-4 -----CCCAGUGUUCAGACUACCUa---------------------------------------------- 2 0,-4 -----CCCAGUGUUCAGACUACCUaa--------------------------------------------- 7 0,-4 -----CCCAGUGUUCAGACUACCUau--------------------------------------------- 20 0,-4 -----CCCAGUGUUCAGACUACCUu---------------------------------------------- 15 0,-4 -----CCCAGUGUUCAGACUACCUuu--------------------------------------------- 42 0,-4 -----CCCAGUGUUCAGACUACCUG---------------------------------------------- 1771 0,-3 -----CCCAGUGUUCAGACUACCUGa--------------------------------------------- 373 0,-3 -----CCCAGUGUUCAGACUACCUGaa-------------------------------------------- 21 0,-3 -----CCCAGUGUUCAGACUACCUGau-------------------------------------------- 23 0,-3 -----CCCAGUGUUCAGACUACCUGc--------------------------------------------- 18 0,-3 -----CCCAGUGUUCAGACUACCUGg--------------------------------------------- 25 0,-3 -----CCCAGUGUUCAGACUACCUGU--------------------------------------------- 19122 0,-2 -----CCCAGUGUUCAGACUACCUGUa-------------------------------------------- 447 0,-2 -----CCCAGUGUUCAGACUACCUGUaa------------------------------------------- 113 0,-2 -----CCCAGUGUUCAGACUACCUGUau------------------------------------------- 16 0,-2 -----CCCAGUGUUCAGACUACCUGUc-------------------------------------------- 126 0,-2 -----CCCAGUGUUCAGACUACCUGUg-------------------------------------------- 36 0,-2 -----CCCAGUGUUCAGACUACCUGUU-------------------------------------------- 98957 0,-1 -----CCCAGUGUUCAGACUACCUGUUa------------------------------------------- 2908 0,-1 -----CCCAGUGUUCAGACUACCUGUUaa------------------------------------------ 170 0,-1 -----CCCAGUGUUCAGACUACCUGUUau------------------------------------------ 63 0,-1 -----CCCAGUGUUCAGACUACCUGUUg------------------------------------------- 114 0,-1 -----CCCAGUGUUCAGACUACCUGUUu------------------------------------------- 9012 0,-1 -----CCCAGUGUUCAGACUACCUGUUuu------------------------------------------ 162 0,-1 -----CCCAGUGUUCAGACUACCUGUUC------------------------------------------- 114789 0,0 -----CCCAGUGUUCAGACUACCUGUUCc------------------------------------------ 43 0,0 -----CCCAGUGUUCAGACUACCUGUUCg------------------------------------------ 73 0,0 -----CCCAGUGUUCAGACUACCUGUUCu------------------------------------------ 4780 0,0 -----CCCAGUGUUCAGACUACCUGUUCuu----------------------------------------- 18 0,0 -----CCCAGUGUUCAGACUACCUGUUCA------------------------------------------ 1180 0,1 -----CCCAGUGUUCAGACUACCUGUUCAa----------------------------------------- 2 0,1 -----CCCAGUGUUCAGACUACCUGUUCAu----------------------------------------- 2 0,1 ------CCAGUGUUCAGACUACCU----------------------------------------------- 2 1,-4 ------CCAGUGUUCAGACUACCUG---------------------------------------------- 8 1,-3 ------CCAGUGUUCAGACUACCUGa--------------------------------------------- 2 1,-3 ------CCAGUGUUCAGACUACCUGU--------------------------------------------- 572 1,-2 ------CCAGUGUUCAGACUACCUGUU-------------------------------------------- 2845 1,-1 ------CCAGUGUUCAGACUACCUGUUa------------------------------------------- 70 1,-1 ------CCAGUGUUCAGACUACCUGUUaa------------------------------------------ 2 1,-1 ------CCAGUGUUCAGACUACCUGUUu------------------------------------------- 219 1,-1 ------CCAGUGUUCAGACUACCUGUUC------------------------------------------- 3150 1,0 ------CCAGUGUUCAGACUACCUGUUCu------------------------------------------ 107 1,0 ------CCAGUGUUCAGACUACCUGUUCA------------------------------------------ 19 1,1 -------CAGUGUUCAGACUACCUGU--------------------------------------------- 22 2,-2 -------CAGUGUUCAGACUACCUGUU-------------------------------------------- 242 2,-1 -------CAGUGUUCAGACUACCUGUUa------------------------------------------- 2 2,-1 -------CAGUGUUCAGACUACCUGUUu------------------------------------------- 8 2,-1 -------CAGUGUUCAGACUACCUGUUC------------------------------------------- 261 2,0 -------CAGUGUUCAGACUACCUGUUCu------------------------------------------ 4 2,0 --------------------------------------------GUACAGUAGUCUGCACAUUGGUU---- 4 -2,-1 ---------------------------------------------UACAGUAGUCUGCACAUU-------- 102 -1,-5 ---------------------------------------------UACAGUAGUCUGCACAUUu------- 3 -1,-5 ---------------------------------------------UACAGUAGUCUGCACAUUG------- 113 -1,-4 ---------------------------------------------UACAGUAGUCUGCACAUUGa------ 26 -1,-4 ---------------------------------------------UACAGUAGUCUGCACAUUGaa----- 2 -1,-4 ---------------------------------------------UACAGUAGUCUGCACAUUGau----- 4 -1,-4 ---------------------------------------------UACAGUAGUCUGCACAUUGu------ 2 -1,-4 ---------------------------------------------UACAGUAGUCUGCACAUUGuu----- 12 -1,-4 ---------------------------------------------UACAGUAGUCUGCACAUUGG------ 596 -1,-3 ---------------------------------------------UACAGUAGUCUGCACAUUGGa----- 79 -1,-3 ---------------------------------------------UACAGUAGUCUGCACAUUGGaa---- 11 -1,-3 ---------------------------------------------UACAGUAGUCUGCACAUUGGau---- 6 -1,-3 ---------------------------------------------UACAGUAGUCUGCACAUUGGc----- 2 -1,-3 ---------------------------------------------UACAGUAGUCUGCACAUUGGg----- 4 -1,-3 ---------------------------------------------UACAGUAGUCUGCACAUUGGU----- 4572 -1,-2 ---------------------------------------------UACAGUAGUCUGCACAUUGGUa---- 678 -1,-2 ---------------------------------------------UACAGUAGUCUGCACAUUGGUaa--- 473 -1,-2 ---------------------------------------------UACAGUAGUCUGCACAUUGGUau--- 90 -1,-2 ---------------------------------------------UACAGUAGUCUGCACAUUGGUc---- 25 -1,-2 ---------------------------------------------UACAGUAGUCUGCACAUUGGUg---- 4 -1,-2 ---------------------------------------------UACAGUAGUCUGCACAUUGGUU---- 26609 -1,-1 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUc--- 26 -1,-1 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUg--- 67 -1,-1 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUu--- 3791 -1,-1 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUuu-- 168 -1,-1 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUA--- 5067 -1,0 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUAa-- 545 -1,0 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUAaa- 16 -1,0 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUAau- 2 -1,0 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUAu-- 612 -1,0 ---------------------------------------------UACAGUAGUCUGCACAUUGGUUAG-- 14 -1,1 ----------------------------------------------ACAGUAGUCUGCACAUUG------- 2431 0,-4 ----------------------------------------------ACAGUAGUCUGCACAUUGa------ 462 0,-4 ----------------------------------------------ACAGUAGUCUGCACAUUGaa----- 77 0,-4 ----------------------------------------------ACAGUAGUCUGCACAUUGau----- 61 0,-4 ----------------------------------------------ACAGUAGUCUGCACAUUGu------ 135 0,-4 ----------------------------------------------ACAGUAGUCUGCACAUUGuu----- 78 0,-4 ----------------------------------------------ACAGUAGUCUGCACAUUGG------ 5663 0,-3 ----------------------------------------------ACAGUAGUCUGCACAUUGGa----- 555 0,-3 ----------------------------------------------ACAGUAGUCUGCACAUUGGaa---- 188 0,-3 ----------------------------------------------ACAGUAGUCUGCACAUUGGau---- 265 0,-3 ----------------------------------------------ACAGUAGUCUGCACAUUGGc----- 63 0,-3 ----------------------------------------------ACAGUAGUCUGCACAUUGGg----- 75 0,-3 ----------------------------------------------ACAGUAGUCUGCACAUUGGU----- 28344 0,-2 ----------------------------------------------ACAGUAGUCUGCACAUUGGUa---- 3198 0,-2 ----------------------------------------------ACAGUAGUCUGCACAUUGGUaa--- 3587 0,-2 ----------------------------------------------ACAGUAGUCUGCACAUUGGUau--- 210 0,-2 ----------------------------------------------ACAGUAGUCUGCACAUUGGUc---- 452 0,-2 ----------------------------------------------ACAGUAGUCUGCACAUUGGUg---- 251 0,-2 ----------------------------------------------ACAGUAGUCUGCACAUUGGUU---- 281550 0,-1 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUc--- 739 0,-1 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUg--- 912 0,-1 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUu--- 32091 0,-1 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUuu-- 1587 0,-1 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUA--- 147780 0,0 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUAa-- 48163 0,0 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUAaa- 955 0,0 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUAau- 223 0,0 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUAc-- 431 0,0 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUAu-- 13217 0,0 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUAuu- 68 0,0 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUAG-- 1147 0,1 ----------------------------------------------ACAGUAGUCUGCACAUUGGUUAGu- 13 0,1 -----------------------------------------------CAGUAGUCUGCACAUUGG------ 279 1,-3 -----------------------------------------------CAGUAGUCUGCACAUUGGa----- 23 1,-3 -----------------------------------------------CAGUAGUCUGCACAUUGGaa---- 12 1,-3 -----------------------------------------------CAGUAGUCUGCACAUUGGau---- 11 1,-3 -----------------------------------------------CAGUAGUCUGCACAUUGGc----- 2 1,-3 -----------------------------------------------CAGUAGUCUGCACAUUGGg----- 2 1,-3 -----------------------------------------------CAGUAGUCUGCACAUUGGU----- 2112 1,-2 -----------------------------------------------CAGUAGUCUGCACAUUGGUa---- 279 1,-2 -----------------------------------------------CAGUAGUCUGCACAUUGGUaa--- 339 1,-2 -----------------------------------------------CAGUAGUCUGCACAUUGGUau--- 14 1,-2 -----------------------------------------------CAGUAGUCUGCACAUUGGUc---- 15 1,-2 -----------------------------------------------CAGUAGUCUGCACAUUGGUU---- 24603 1,-1 -----------------------------------------------CAGUAGUCUGCACAUUGGUUc--- 36 1,-1 -----------------------------------------------CAGUAGUCUGCACAUUGGUUg--- 47 1,-1 -----------------------------------------------CAGUAGUCUGCACAUUGGUUu--- 2896 1,-1 -----------------------------------------------CAGUAGUCUGCACAUUGGUUuu-- 143 1,-1 -----------------------------------------------CAGUAGUCUGCACAUUGGUUA--- 17503 1,0 -----------------------------------------------CAGUAGUCUGCACAUUGGUUAa-- 6262 1,0 -----------------------------------------------CAGUAGUCUGCACAUUGGUUAaa- 274 1,0 -----------------------------------------------CAGUAGUCUGCACAUUGGUUAau- 42 1,0 -----------------------------------------------CAGUAGUCUGCACAUUGGUUAc-- 52 1,0 -----------------------------------------------CAGUAGUCUGCACAUUGGUUAu-- 1393 1,0 -----------------------------------------------CAGUAGUCUGCACAUUGGUUAuu- 4 1,0 -----------------------------------------------CAGUAGUCUGCACAUUGGUUAG-- 69 1,1 ------------------------------------------------AGUAGUCUGCACAUUGGU----- 103 2,-2 ------------------------------------------------AGUAGUCUGCACAUUGGUa---- 5 2,-2 ------------------------------------------------AGUAGUCUGCACAUUGGUaa--- 8 2,-2 ------------------------------------------------AGUAGUCUGCACAUUGGUU---- 1413 2,-1 ------------------------------------------------AGUAGUCUGCACAUUGGUUu--- 173 2,-1 ------------------------------------------------AGUAGUCUGCACAUUGGUUuu-- 2 2,-1 ------------------------------------------------AGUAGUCUGCACAUUGGUUA--- 998 2,0 ------------------------------------------------AGUAGUCUGCACAUUGGUUAa-- 377 2,0 ------------------------------------------------AGUAGUCUGCACAUUGGUUAaa- 6 2,0 ------------------------------------------------AGUAGUCUGCACAUUGGUUAu-- 76 2,0 ------------------------------------------------AGUAGUCUGCACAUUGGUUAG-- 4 2,1 >hsa-mir-199a-2 5p:31-53;3p:70-91 Tumor aggaagcuucuggagauccugcuccgucgcCCCAGUGUUCAGACUACCUGUUCaggacaaugccguuguACAGUAGUCUGCACAUUGGUUAgacugggcaagggagagca -----------------------------CCCCAGUGUUCAGACUACCUGU----------------------------------------------------------- 2 -1,-2 -----------------------------CCCCAGUGUUCAGACUACCUGUU---------------------------------------------------------- 25 -1,-1 -----------------------------CCCCAGUGUUCAGACUACCUGUUC--------------------------------------------------------- 25 -1,0 ------------------------------CCCAGUGUUCAGACUACC-------------------------------------------------------------- 490 0,-5 ------------------------------CCCAGUGUUCAGACUACCg------------------------------------------------------------- 2 0,-5 ------------------------------CCCAGUGUUCAGACUACCU------------------------------------------------------------- 1363 0,-4 ------------------------------CCCAGUGUUCAGACUACCUa------------------------------------------------------------ 2 0,-4 ------------------------------CCCAGUGUUCAGACUACCUaa----------------------------------------------------------- 7 0,-4 ------------------------------CCCAGUGUUCAGACUACCUau----------------------------------------------------------- 20 0,-4 ------------------------------CCCAGUGUUCAGACUACCUu------------------------------------------------------------ 15 0,-4 ------------------------------CCCAGUGUUCAGACUACCUuu----------------------------------------------------------- 42 0,-4 ------------------------------CCCAGUGUUCAGACUACCUG------------------------------------------------------------ 1771 0,-3 ------------------------------CCCAGUGUUCAGACUACCUGa----------------------------------------------------------- 373 0,-3 ------------------------------CCCAGUGUUCAGACUACCUGaa---------------------------------------------------------- 21 0,-3 ------------------------------CCCAGUGUUCAGACUACCUGau---------------------------------------------------------- 23 0,-3 ------------------------------CCCAGUGUUCAGACUACCUGc----------------------------------------------------------- 18 0,-3 ------------------------------CCCAGUGUUCAGACUACCUGg----------------------------------------------------------- 25 0,-3 ------------------------------CCCAGUGUUCAGACUACCUGU----------------------------------------------------------- 19122 0,-2 ------------------------------CCCAGUGUUCAGACUACCUGUa---------------------------------------------------------- 447 0,-2 ------------------------------CCCAGUGUUCAGACUACCUGUaa--------------------------------------------------------- 113 0,-2 ------------------------------CCCAGUGUUCAGACUACCUGUau--------------------------------------------------------- 16 0,-2 ------------------------------CCCAGUGUUCAGACUACCUGUc---------------------------------------------------------- 126 0,-2 ------------------------------CCCAGUGUUCAGACUACCUGUg---------------------------------------------------------- 36 0,-2 ------------------------------CCCAGUGUUCAGACUACCUGUU---------------------------------------------------------- 98957 0,-1 ------------------------------CCCAGUGUUCAGACUACCUGUUa--------------------------------------------------------- 2908 0,-1 ------------------------------CCCAGUGUUCAGACUACCUGUUaa-------------------------------------------------------- 170 0,-1 ------------------------------CCCAGUGUUCAGACUACCUGUUau-------------------------------------------------------- 63 0,-1 ------------------------------CCCAGUGUUCAGACUACCUGUUg--------------------------------------------------------- 114 0,-1 ------------------------------CCCAGUGUUCAGACUACCUGUUu--------------------------------------------------------- 9012 0,-1 ------------------------------CCCAGUGUUCAGACUACCUGUUuu-------------------------------------------------------- 162 0,-1 ------------------------------CCCAGUGUUCAGACUACCUGUUC--------------------------------------------------------- 114789 0,0 ------------------------------CCCAGUGUUCAGACUACCUGUUCc-------------------------------------------------------- 43 0,0 ------------------------------CCCAGUGUUCAGACUACCUGUUCg-------------------------------------------------------- 73 0,0 ------------------------------CCCAGUGUUCAGACUACCUGUUCu-------------------------------------------------------- 4780 0,0 ------------------------------CCCAGUGUUCAGACUACCUGUUCuu------------------------------------------------------- 18 0,0 ------------------------------CCCAGUGUUCAGACUACCUGUUCA-------------------------------------------------------- 1180 0,1 ------------------------------CCCAGUGUUCAGACUACCUGUUCAa------------------------------------------------------- 2 0,1 ------------------------------CCCAGUGUUCAGACUACCUGUUCAu------------------------------------------------------- 2 0,1 -------------------------------CCAGUGUUCAGACUACCU------------------------------------------------------------- 2 1,-4 -------------------------------CCAGUGUUCAGACUACCUG------------------------------------------------------------ 8 1,-3 -------------------------------CCAGUGUUCAGACUACCUGa----------------------------------------------------------- 2 1,-3 -------------------------------CCAGUGUUCAGACUACCUGU----------------------------------------------------------- 572 1,-2 -------------------------------CCAGUGUUCAGACUACCUGUU---------------------------------------------------------- 2845 1,-1 -------------------------------CCAGUGUUCAGACUACCUGUUa--------------------------------------------------------- 70 1,-1 -------------------------------CCAGUGUUCAGACUACCUGUUaa-------------------------------------------------------- 2 1,-1 -------------------------------CCAGUGUUCAGACUACCUGUUu--------------------------------------------------------- 219 1,-1 -------------------------------CCAGUGUUCAGACUACCUGUUC--------------------------------------------------------- 3150 1,0 -------------------------------CCAGUGUUCAGACUACCUGUUCu-------------------------------------------------------- 107 1,0 -------------------------------CCAGUGUUCAGACUACCUGUUCA-------------------------------------------------------- 19 1,1 --------------------------------CAGUGUUCAGACUACCUGU----------------------------------------------------------- 22 2,-2 --------------------------------CAGUGUUCAGACUACCUGUU---------------------------------------------------------- 242 2,-1 --------------------------------CAGUGUUCAGACUACCUGUUa--------------------------------------------------------- 2 2,-1 --------------------------------CAGUGUUCAGACUACCUGUUu--------------------------------------------------------- 8 2,-1 --------------------------------CAGUGUUCAGACUACCUGUUC--------------------------------------------------------- 261 2,0 --------------------------------CAGUGUUCAGACUACCUGUUCu-------------------------------------------------------- 4 2,0 -------------------------------------------------------------------GUACAGUAGUCUGCACAUUGGUU-------------------- 4 -2,-1 --------------------------------------------------------------------UACAGUAGUCUGCACAUU------------------------ 102 -1,-5 --------------------------------------------------------------------UACAGUAGUCUGCACAUUu----------------------- 3 -1,-5 --------------------------------------------------------------------UACAGUAGUCUGCACAUUG----------------------- 113 -1,-4 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGa---------------------- 26 -1,-4 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGaa--------------------- 2 -1,-4 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGau--------------------- 4 -1,-4 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGu---------------------- 2 -1,-4 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGuu--------------------- 12 -1,-4 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGG---------------------- 596 -1,-3 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGa--------------------- 79 -1,-3 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGaa-------------------- 11 -1,-3 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGau-------------------- 6 -1,-3 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGc--------------------- 2 -1,-3 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGg--------------------- 4 -1,-3 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGU--------------------- 4572 -1,-2 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUa-------------------- 678 -1,-2 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUaa------------------- 473 -1,-2 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUau------------------- 90 -1,-2 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUc-------------------- 25 -1,-2 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUg-------------------- 4 -1,-2 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUU-------------------- 26609 -1,-1 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUc------------------- 26 -1,-1 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUg------------------- 67 -1,-1 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUu------------------- 3791 -1,-1 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUuu------------------ 168 -1,-1 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUA------------------- 5067 -1,0 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAa------------------ 545 -1,0 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAaa----------------- 16 -1,0 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAau----------------- 2 -1,0 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAu------------------ 612 -1,0 --------------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAG------------------ 14 -1,1 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUG----------------------- 2431 0,-4 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGa---------------------- 462 0,-4 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGaa--------------------- 77 0,-4 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGau--------------------- 61 0,-4 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGu---------------------- 135 0,-4 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGuu--------------------- 78 0,-4 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGG---------------------- 5663 0,-3 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGa--------------------- 555 0,-3 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGaa-------------------- 188 0,-3 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGau-------------------- 265 0,-3 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGc--------------------- 63 0,-3 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGg--------------------- 75 0,-3 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGU--------------------- 28344 0,-2 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUa-------------------- 3198 0,-2 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUaa------------------- 3587 0,-2 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUau------------------- 210 0,-2 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUc-------------------- 452 0,-2 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUg-------------------- 251 0,-2 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUU-------------------- 281550 0,-1 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUc------------------- 739 0,-1 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUg------------------- 912 0,-1 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUu------------------- 32091 0,-1 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUuu------------------ 1587 0,-1 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUA------------------- 147780 0,0 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAa------------------ 48163 0,0 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAaa----------------- 955 0,0 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAau----------------- 223 0,0 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAc------------------ 431 0,0 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAu------------------ 13217 0,0 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAuu----------------- 68 0,0 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAG------------------ 1147 0,1 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAGu----------------- 13 0,1 ---------------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAGA----------------- 70 0,2 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGG---------------------- 279 1,-3 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGa--------------------- 23 1,-3 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGaa-------------------- 12 1,-3 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGau-------------------- 11 1,-3 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGc--------------------- 2 1,-3 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGg--------------------- 2 1,-3 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGU--------------------- 2112 1,-2 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUa-------------------- 279 1,-2 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUaa------------------- 339 1,-2 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUau------------------- 14 1,-2 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUc-------------------- 15 1,-2 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUU-------------------- 24603 1,-1 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUc------------------- 36 1,-1 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUg------------------- 47 1,-1 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUu------------------- 2896 1,-1 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUuu------------------ 143 1,-1 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUA------------------- 17503 1,0 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAa------------------ 6262 1,0 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAaa----------------- 274 1,0 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAau----------------- 42 1,0 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAc------------------ 52 1,0 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAu------------------ 1393 1,0 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAuu----------------- 4 1,0 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAG------------------ 69 1,1 ----------------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAGA----------------- 6 1,2 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGU--------------------- 103 2,-2 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUa-------------------- 5 2,-2 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUaa------------------- 8 2,-2 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUU-------------------- 1413 2,-1 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUUu------------------- 173 2,-1 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUUuu------------------ 2 2,-1 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUUA------------------- 998 2,0 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUUAa------------------ 377 2,0 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUUAaa----------------- 6 2,0 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUUAu------------------ 76 2,0 -----------------------------------------------------------------------AGUAGUCUGCACAUUGGUUAG------------------ 4 2,1 >hsa-mir-199b 5p:26-48;3p:65-86 Tumor ccagaggacaccuccacuccgucuaCCCAGUGUUUAGACUAUCUGUUCaggacucccaaauuguACAGUAGUCUGCACAUUGGUUAggcugggcuggguuagacccucgg -------------------------CCCAGUGUUUAGACUAUC------------------------------------------------------------------- 35 0,-5 -------------------------CCCAGUGUUUAGACUAUCa------------------------------------------------------------------ 2 0,-5 -------------------------CCCAGUGUUUAGACUAUCU------------------------------------------------------------------ 393 0,-4 -------------------------CCCAGUGUUUAGACUAUCUa----------------------------------------------------------------- 4 0,-4 -------------------------CCCAGUGUUUAGACUAUCUau---------------------------------------------------------------- 4 0,-4 -------------------------CCCAGUGUUUAGACUAUCUuu---------------------------------------------------------------- 6 0,-4 -------------------------CCCAGUGUUUAGACUAUCUG----------------------------------------------------------------- 350 0,-3 -------------------------CCCAGUGUUUAGACUAUCUGa---------------------------------------------------------------- 120 0,-3 -------------------------CCCAGUGUUUAGACUAUCUGaa--------------------------------------------------------------- 4 0,-3 -------------------------CCCAGUGUUUAGACUAUCUGc---------------------------------------------------------------- 5 0,-3 -------------------------CCCAGUGUUUAGACUAUCUGg---------------------------------------------------------------- 2 0,-3 -------------------------CCCAGUGUUUAGACUAUCUGU---------------------------------------------------------------- 3478 0,-2 -------------------------CCCAGUGUUUAGACUAUCUGUa--------------------------------------------------------------- 68 0,-2 -------------------------CCCAGUGUUUAGACUAUCUGUaa-------------------------------------------------------------- 4 0,-2 -------------------------CCCAGUGUUUAGACUAUCUGUc--------------------------------------------------------------- 16 0,-2 -------------------------CCCAGUGUUUAGACUAUCUGUU--------------------------------------------------------------- 14613 0,-1 -------------------------CCCAGUGUUUAGACUAUCUGUUa-------------------------------------------------------------- 895 0,-1 -------------------------CCCAGUGUUUAGACUAUCUGUUaa------------------------------------------------------------- 32 0,-1 -------------------------CCCAGUGUUUAGACUAUCUGUUg-------------------------------------------------------------- 23 0,-1 -------------------------CCCAGUGUUUAGACUAUCUGUUu-------------------------------------------------------------- 586 0,-1 -------------------------CCCAGUGUUUAGACUAUCUGUUuu------------------------------------------------------------- 4 0,-1 -------------------------CCCAGUGUUUAGACUAUCUGUUC-------------------------------------------------------------- 17358 0,0 -------------------------CCCAGUGUUUAGACUAUCUGUUCc------------------------------------------------------------- 19 0,0 -------------------------CCCAGUGUUUAGACUAUCUGUUCg------------------------------------------------------------- 17 0,0 -------------------------CCCAGUGUUUAGACUAUCUGUUCu------------------------------------------------------------- 512 0,0 -------------------------CCCAGUGUUUAGACUAUCUGUUCA------------------------------------------------------------- 354 0,1 -------------------------CCCAGUGUUUAGACUAUCUGUUCAa------------------------------------------------------------ 2 0,1 --------------------------CCAGUGUUUAGACUAUCU------------------------------------------------------------------ 2 1,-4 --------------------------CCAGUGUUUAGACUAUCUG----------------------------------------------------------------- 2 1,-3 --------------------------CCAGUGUUUAGACUAUCUGU---------------------------------------------------------------- 94 1,-2 --------------------------CCAGUGUUUAGACUAUCUGUU--------------------------------------------------------------- 626 1,-1 --------------------------CCAGUGUUUAGACUAUCUGUUa-------------------------------------------------------------- 23 1,-1 --------------------------CCAGUGUUUAGACUAUCUGUUu-------------------------------------------------------------- 14 1,-1 --------------------------CCAGUGUUUAGACUAUCUGUUC-------------------------------------------------------------- 592 1,0 --------------------------CCAGUGUUUAGACUAUCUGUUCu------------------------------------------------------------- 2 1,0 --------------------------CCAGUGUUUAGACUAUCUGUUCA------------------------------------------------------------- 5 1,1 ---------------------------CAGUGUUUAGACUAUCUGU---------------------------------------------------------------- 7 2,-2 ---------------------------CAGUGUUUAGACUAUCUGUU--------------------------------------------------------------- 102 2,-1 ---------------------------CAGUGUUUAGACUAUCUGUUa-------------------------------------------------------------- 6 2,-1 ---------------------------CAGUGUUUAGACUAUCUGUUu-------------------------------------------------------------- 2 2,-1 ---------------------------CAGUGUUUAGACUAUCUGUUC-------------------------------------------------------------- 83 2,0 ---------------------------CAGUGUUUAGACUAUCUGUUCA------------------------------------------------------------- 2 2,1 --------------------------------------------------------------GUACAGUAGUCUGCACAUUGGUU------------------------- 4 -2,-1 ---------------------------------------------------------------UACAGUAGUCUGCACAUU----------------------------- 102 -1,-5 ---------------------------------------------------------------UACAGUAGUCUGCACAUUu---------------------------- 3 -1,-5 ---------------------------------------------------------------UACAGUAGUCUGCACAUUG---------------------------- 113 -1,-4 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGa--------------------------- 26 -1,-4 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGaa-------------------------- 2 -1,-4 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGau-------------------------- 4 -1,-4 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGu--------------------------- 2 -1,-4 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGuu-------------------------- 12 -1,-4 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGG--------------------------- 596 -1,-3 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGa-------------------------- 79 -1,-3 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGaa------------------------- 11 -1,-3 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGau------------------------- 6 -1,-3 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGc-------------------------- 2 -1,-3 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGg-------------------------- 4 -1,-3 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGU-------------------------- 4572 -1,-2 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUa------------------------- 678 -1,-2 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUaa------------------------ 473 -1,-2 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUau------------------------ 90 -1,-2 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUc------------------------- 25 -1,-2 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUg------------------------- 4 -1,-2 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUU------------------------- 26609 -1,-1 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUc------------------------ 26 -1,-1 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUg------------------------ 67 -1,-1 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUu------------------------ 3791 -1,-1 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUuu----------------------- 168 -1,-1 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUA------------------------ 5067 -1,0 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAa----------------------- 545 -1,0 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAaa---------------------- 16 -1,0 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAau---------------------- 2 -1,0 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAu----------------------- 612 -1,0 ---------------------------------------------------------------UACAGUAGUCUGCACAUUGGUUAG----------------------- 14 -1,1 ----------------------------------------------------------------ACAGUAGUCUGCACAUUG---------------------------- 2431 0,-4 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGa--------------------------- 462 0,-4 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGaa-------------------------- 77 0,-4 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGau-------------------------- 61 0,-4 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGu--------------------------- 135 0,-4 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGuu-------------------------- 78 0,-4 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGG--------------------------- 5663 0,-3 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGa-------------------------- 555 0,-3 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGaa------------------------- 188 0,-3 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGau------------------------- 265 0,-3 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGc-------------------------- 63 0,-3 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGg-------------------------- 75 0,-3 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGU-------------------------- 28344 0,-2 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUa------------------------- 3198 0,-2 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUaa------------------------ 3587 0,-2 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUau------------------------ 210 0,-2 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUc------------------------- 452 0,-2 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUg------------------------- 251 0,-2 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUU------------------------- 281550 0,-1 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUc------------------------ 739 0,-1 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUg------------------------ 912 0,-1 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUu------------------------ 32091 0,-1 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUuu----------------------- 1587 0,-1 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUA------------------------ 147780 0,0 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAa----------------------- 48163 0,0 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAaa---------------------- 955 0,0 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAau---------------------- 223 0,0 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAc----------------------- 431 0,0 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAu----------------------- 13217 0,0 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAuu---------------------- 68 0,0 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAG----------------------- 1147 0,1 ----------------------------------------------------------------ACAGUAGUCUGCACAUUGGUUAGu---------------------- 13 0,1 -----------------------------------------------------------------CAGUAGUCUGCACAUUGG--------------------------- 279 1,-3 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGa-------------------------- 23 1,-3 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGaa------------------------- 12 1,-3 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGau------------------------- 11 1,-3 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGc-------------------------- 2 1,-3 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGg-------------------------- 2 1,-3 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGU-------------------------- 2112 1,-2 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUa------------------------- 279 1,-2 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUaa------------------------ 339 1,-2 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUau------------------------ 14 1,-2 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUc------------------------- 15 1,-2 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUU------------------------- 24603 1,-1 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUc------------------------ 36 1,-1 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUg------------------------ 47 1,-1 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUu------------------------ 2896 1,-1 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUuu----------------------- 143 1,-1 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUA------------------------ 17503 1,0 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAa----------------------- 6262 1,0 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAaa---------------------- 274 1,0 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAau---------------------- 42 1,0 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAc----------------------- 52 1,0 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAu----------------------- 1393 1,0 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAuu---------------------- 4 1,0 -----------------------------------------------------------------CAGUAGUCUGCACAUUGGUUAG----------------------- 69 1,1 ------------------------------------------------------------------AGUAGUCUGCACAUUGGU-------------------------- 103 2,-2 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUa------------------------- 5 2,-2 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUaa------------------------ 8 2,-2 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUU------------------------- 1413 2,-1 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUUu------------------------ 173 2,-1 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUUuu----------------------- 2 2,-1 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUUA------------------------ 998 2,0 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUUAa----------------------- 377 2,0 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUUAaa---------------------- 6 2,0 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUUAu----------------------- 76 2,0 ------------------------------------------------------------------AGUAGUCUGCACAUUGGUUAG----------------------- 4 2,1 >hsa-mir-19a mi:14-35;MA:49-71 Tumor gcaguccucuguuAGUUUUGCAUAGUUGCACUACAagaagaauguaguUGUGCAAAUCUAUGCAAAACUGAugguggccugc ------------UAGUUUUGCAUAGUUGCACU-------------------------------------------------- 2 -1,-3 ------------UAGUUUUGCAUAGUUGCACUAC------------------------------------------------ 8 -1,-1 -------------AGUUUUGCAUAGUUGCACU-------------------------------------------------- 2 0,-3 -------------AGUUUUGCAUAGUUGCACUA------------------------------------------------- 27 0,-2 -------------AGUUUUGCAUAGUUGCACUAC------------------------------------------------ 37 0,-1 -----------------------------------------------UUGUGCAAAUCUAUGCAAA---------------- 13 -1,-5 -----------------------------------------------UUGUGCAAAUCUAUGCAAAA--------------- 9 -1,-4 -----------------------------------------------UUGUGCAAAUCUAUGCAAAAa-------------- 2 -1,-4 -----------------------------------------------UUGUGCAAAUCUAUGCAAAAau------------- 2 -1,-4 -----------------------------------------------UUGUGCAAAUCUAUGCAAAAC-------------- 153 -1,-3 -----------------------------------------------UUGUGCAAAUCUAUGCAAAACU------------- 1000 -1,-2 -----------------------------------------------UUGUGCAAAUCUAUGCAAAACUG------------ 1169 -1,-1 -----------------------------------------------UUGUGCAAAUCUAUGCAAAACUGu----------- 37 -1,-1 -----------------------------------------------UUGUGCAAAUCUAUGCAAAACUGA----------- 1650 -1,0 -----------------------------------------------UUGUGCAAAUCUAUGCAAAACUGAU---------- 16 -1,1 ------------------------------------------------UGUGCAAAUCUAUGCAAA---------------- 251 0,-5 ------------------------------------------------UGUGCAAAUCUAUGCAAAA--------------- 396 0,-4 ------------------------------------------------UGUGCAAAUCUAUGCAAAAa-------------- 17 0,-4 ------------------------------------------------UGUGCAAAUCUAUGCAAAAau------------- 4 0,-4 ------------------------------------------------UGUGCAAAUCUAUGCAAAAC-------------- 942 0,-3 ------------------------------------------------UGUGCAAAUCUAUGCAAAACa------------- 4 0,-3 ------------------------------------------------UGUGCAAAUCUAUGCAAAACU------------- 2210 0,-2 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUa------------ 22 0,-2 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUaa----------- 60 0,-2 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUu------------ 15 0,-2 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUG------------ 13141 0,-1 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUGc----------- 127 0,-1 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUGg----------- 34 0,-1 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUGu----------- 1015 0,-1 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUGuu---------- 15 0,-1 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUGA----------- 43885 0,0 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUGAa---------- 181 0,0 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUGAaa--------- 5 0,0 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUGAc---------- 6 0,0 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUGAU---------- 568 0,1 ------------------------------------------------UGUGCAAAUCUAUGCAAAACUGAUu--------- 65 0,1 -------------------------------------------------GUGCAAAUCUAUGCAAAAa-------------- 2 1,-4 -------------------------------------------------GUGCAAAUCUAUGCAAAAC-------------- 17 1,-3 -------------------------------------------------GUGCAAAUCUAUGCAAAACU------------- 62 1,-2 -------------------------------------------------GUGCAAAUCUAUGCAAAACUG------------ 616 1,-1 -------------------------------------------------GUGCAAAUCUAUGCAAAACUGu----------- 12 1,-1 -------------------------------------------------GUGCAAAUCUAUGCAAAACUGA----------- 955 1,0 -------------------------------------------------GUGCAAAUCUAUGCAAAACUGAU---------- 2 1,1 >hsa-mir-19b-1 mi:16-38;MA:54-76 Tumor cacuguucuaugguuAGUUUUGCAGGUUUGCAUCCAGCugugugauauucugcUGUGCAAAUCCAUGCAAAACUGAcugugguagug ---------------AGUUUUGCAGGUUUGCAUC----------------------------------------------------- 6 0,-4 ---------------AGUUUUGCAGGUUUGCAUCC---------------------------------------------------- 14 0,-3 ---------------AGUUUUGCAGGUUUGCAUCCA--------------------------------------------------- 6 0,-2 ---------------AGUUUUGCAGGUUUGCAUCCAG-------------------------------------------------- 85 0,-1 ---------------AGUUUUGCAGGUUUGCAUCCAGa------------------------------------------------- 33 0,-1 ---------------AGUUUUGCAGGUUUGCAUCCAGu------------------------------------------------- 26 0,-1 ---------------AGUUUUGCAGGUUUGCAUCCAGC------------------------------------------------- 450 0,0 ---------------AGUUUUGCAGGUUUGCAUCCAGCU------------------------------------------------ 4 0,1 -----------------UUUUGCAGGUUUGCAUCCAGC------------------------------------------------- 2 2,0 ----------------------------------------------------CUGUGCAAAUCCAUGCAAAAC-------------- 36 -1,-3 ----------------------------------------------------CUGUGCAAAUCCAUGCAAAACU------------- 173 -1,-2 ----------------------------------------------------CUGUGCAAAUCCAUGCAAAACUG------------ 670 -1,-1 ----------------------------------------------------CUGUGCAAAUCCAUGCAAAACUGu----------- 20 -1,-1 ----------------------------------------------------CUGUGCAAAUCCAUGCAAAACUGA----------- 896 -1,0 -----------------------------------------------------UGUGCAAAUCCAUGCAAA---------------- 1883 0,-5 -----------------------------------------------------UGUGCAAAUCCAUGCAAAg--------------- 2 0,-5 -----------------------------------------------------UGUGCAAAUCCAUGCAAAA--------------- 2454 0,-4 -----------------------------------------------------UGUGCAAAUCCAUGCAAAAa-------------- 241 0,-4 -----------------------------------------------------UGUGCAAAUCCAUGCAAAAaa------------- 8 0,-4 -----------------------------------------------------UGUGCAAAUCCAUGCAAAAau------------- 66 0,-4 -----------------------------------------------------UGUGCAAAUCCAUGCAAAAg-------------- 6 0,-4 -----------------------------------------------------UGUGCAAAUCCAUGCAAAAu-------------- 10 0,-4 -----------------------------------------------------UGUGCAAAUCCAUGCAAAAuu------------- 14 0,-4 -----------------------------------------------------UGUGCAAAUCCAUGCAAAAC-------------- 7060 0,-3 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACa------------- 95 0,-3 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACc------------- 20 0,-3 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACg------------- 13 0,-3 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACU------------- 19177 0,-2 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUa------------ 207 0,-2 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUaa----------- 327 0,-2 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUc------------ 24 0,-2 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUu------------ 121 0,-2 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUG------------ 97332 0,-1 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGc----------- 750 0,-1 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGg----------- 219 0,-1 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGu----------- 5360 0,-1 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGuu---------- 53 0,-1 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGA----------- 173750 0,0 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGAa---------- 705 0,0 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGAaa--------- 27 0,0 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGAau--------- 4 0,0 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGAg---------- 11 0,0 -----------------------------------------------------UGUGCAAAUCCAUGCAAAACUGAC---------- 20 0,1 ------------------------------------------------------GUGCAAAUCCAUGCAAAA--------------- 35 1,-4 ------------------------------------------------------GUGCAAAUCCAUGCAAAAau------------- 6 1,-4 ------------------------------------------------------GUGCAAAUCCAUGCAAAAC-------------- 176 1,-3 ------------------------------------------------------GUGCAAAUCCAUGCAAAACa------------- 2 1,-3 ------------------------------------------------------GUGCAAAUCCAUGCAAAACU------------- 523 1,-2 ------------------------------------------------------GUGCAAAUCCAUGCAAAACUG------------ 4073 1,-1 ------------------------------------------------------GUGCAAAUCCAUGCAAAACUGc----------- 6 1,-1 ------------------------------------------------------GUGCAAAUCCAUGCAAAACUGu----------- 163 1,-1 ------------------------------------------------------GUGCAAAUCCAUGCAAAACUGA----------- 3595 1,0 ------------------------------------------------------GUGCAAAUCCAUGCAAAACUGAa---------- 11 1,0 -------------------------------------------------------UGCAAAUCCAUGCAAAACUG------------ 14 2,-1 -------------------------------------------------------UGCAAAUCCAUGCAAAACUGA----------- 4 2,0 >hsa-mir-19b-2 mi:19-40;MA:62-84 Tumor acauugcuacuuacaauuAGUUUUGCAGGUUUGCAUUUCAgcguauauauguauauguggcUGUGCAAAUCCAUGCAAAACUGAuugugauaaugu ------------------------------------------------------------CUGUGCAAAUCCAUGCAAAAC--------------- 36 -1,-3 ------------------------------------------------------------CUGUGCAAAUCCAUGCAAAACU-------------- 173 -1,-2 ------------------------------------------------------------CUGUGCAAAUCCAUGCAAAACUG------------- 670 -1,-1 ------------------------------------------------------------CUGUGCAAAUCCAUGCAAAACUGu------------ 20 -1,-1 ------------------------------------------------------------CUGUGCAAAUCCAUGCAAAACUGA------------ 896 -1,0 ------------------------------------------------------------CUGUGCAAAUCCAUGCAAAACUGAU----------- 2 -1,1 -------------------------------------------------------------UGUGCAAAUCCAUGCAAA----------------- 1883 0,-5 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAg---------------- 2 0,-5 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAA---------------- 2454 0,-4 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAAa--------------- 241 0,-4 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAAaa-------------- 8 0,-4 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAAau-------------- 66 0,-4 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAAg--------------- 6 0,-4 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAAu--------------- 10 0,-4 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAAuu-------------- 14 0,-4 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAAC--------------- 7060 0,-3 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACa-------------- 95 0,-3 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACc-------------- 20 0,-3 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACg-------------- 13 0,-3 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACU-------------- 19177 0,-2 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUa------------- 207 0,-2 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUaa------------ 327 0,-2 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUc------------- 24 0,-2 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUu------------- 121 0,-2 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUG------------- 97332 0,-1 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGc------------ 750 0,-1 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGg------------ 219 0,-1 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGu------------ 5360 0,-1 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGuu----------- 53 0,-1 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGA------------ 173750 0,0 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGAa----------- 705 0,0 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGAaa---------- 27 0,0 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGAau---------- 4 0,0 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGAg----------- 11 0,0 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGAU----------- 934 0,1 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGAUa---------- 6 0,1 -------------------------------------------------------------UGUGCAAAUCCAUGCAAAACUGAUU---------- 36 0,2 --------------------------------------------------------------GUGCAAAUCCAUGCAAAA---------------- 35 1,-4 --------------------------------------------------------------GUGCAAAUCCAUGCAAAAau-------------- 6 1,-4 --------------------------------------------------------------GUGCAAAUCCAUGCAAAAC--------------- 176 1,-3 --------------------------------------------------------------GUGCAAAUCCAUGCAAAACa-------------- 2 1,-3 --------------------------------------------------------------GUGCAAAUCCAUGCAAAACU-------------- 523 1,-2 --------------------------------------------------------------GUGCAAAUCCAUGCAAAACUG------------- 4073 1,-1 --------------------------------------------------------------GUGCAAAUCCAUGCAAAACUGc------------ 6 1,-1 --------------------------------------------------------------GUGCAAAUCCAUGCAAAACUGu------------ 163 1,-1 --------------------------------------------------------------GUGCAAAUCCAUGCAAAACUGA------------ 3595 1,0 --------------------------------------------------------------GUGCAAAUCCAUGCAAAACUGAa----------- 11 1,0 --------------------------------------------------------------GUGCAAAUCCAUGCAAAACUGAU----------- 6 1,1 ---------------------------------------------------------------UGCAAAUCCAUGCAAAACUG------------- 14 2,-1 ---------------------------------------------------------------UGCAAAUCCAUGCAAAACUGA------------ 4 2,0 >hsa-mir-200a mi:16-37;MA:54-75 Tumor ccgggccccugugagCAUCUUACCGGACAGUGCUGGAuuucccagcuugacucUAACACUGUCUGGUAACGAUGUucaaaggugacccgc ---------------CAUCUUACCGGACAGUGCUG------------------------------------------------------- 10 0,-2 ---------------CAUCUUACCGGACAGUGCUGu------------------------------------------------------ 2 0,-2 ---------------CAUCUUACCGGACAGUGCUGG------------------------------------------------------ 268 0,-1 ---------------CAUCUUACCGGACAGUGCUGGc----------------------------------------------------- 2 0,-1 ---------------CAUCUUACCGGACAGUGCUGGu----------------------------------------------------- 4 0,-1 ---------------CAUCUUACCGGACAGUGCUGGA----------------------------------------------------- 586 0,0 ---------------CAUCUUACCGGACAGUGCUGGAa---------------------------------------------------- 81 0,0 ---------------CAUCUUACCGGACAGUGCUGGAaa--------------------------------------------------- 2 0,0 ---------------CAUCUUACCGGACAGUGCUGGAg---------------------------------------------------- 2 0,0 ---------------CAUCUUACCGGACAGUGCUGGAU---------------------------------------------------- 20 0,1 ----------------AUCUUACCGGACAGUGCUGG------------------------------------------------------ 12 1,-1 ----------------AUCUUACCGGACAGUGCUGGA----------------------------------------------------- 71 1,0 ----------------AUCUUACCGGACAGUGCUGGAa---------------------------------------------------- 8 1,0 ----------------AUCUUACCGGACAGUGCUGGAaa--------------------------------------------------- 2 1,0 ----------------AUCUUACCGGACAGUGCUGGAU---------------------------------------------------- 50 1,1 ---------------------------------------------------UCUAACACUGUCUGGUAACGAUGU--------------- 8 -2,0 ---------------------------------------------------UCUAACACUGUCUGGUAACGAUGUU-------------- 24 -2,1 ----------------------------------------------------CUAACACUGUCUGGUAACGA------------------ 4 -1,-3 ----------------------------------------------------CUAACACUGUCUGGUAACGAU----------------- 10 -1,-2 ----------------------------------------------------CUAACACUGUCUGGUAACGAUG---------------- 57 -1,-1 ----------------------------------------------------CUAACACUGUCUGGUAACGAUGU--------------- 153 -1,0 ----------------------------------------------------CUAACACUGUCUGGUAACGAUGUU-------------- 372 -1,1 ----------------------------------------------------CUAACACUGUCUGGUAACGAUGUUa------------- 2 -1,1 ----------------------------------------------------CUAACACUGUCUGGUAACGAUGUUu------------- 29 -1,1 -----------------------------------------------------UAACACUGUCUGGUAACG------------------- 931 0,-4 -----------------------------------------------------UAACACUGUCUGGUAACGA------------------ 641 0,-3 -----------------------------------------------------UAACACUGUCUGGUAACGAa----------------- 33 0,-3 -----------------------------------------------------UAACACUGUCUGGUAACGAaa---------------- 58 0,-3 -----------------------------------------------------UAACACUGUCUGGUAACGAU----------------- 2280 0,-2 -----------------------------------------------------UAACACUGUCUGGUAACGAUa---------------- 542 0,-2 -----------------------------------------------------UAACACUGUCUGGUAACGAUaa--------------- 51 0,-2 -----------------------------------------------------UAACACUGUCUGGUAACGAUau--------------- 63 0,-2 -----------------------------------------------------UAACACUGUCUGGUAACGAUc---------------- 2 0,-2 -----------------------------------------------------UAACACUGUCUGGUAACGAUu---------------- 67 0,-2 -----------------------------------------------------UAACACUGUCUGGUAACGAUuu--------------- 86 0,-2 -----------------------------------------------------UAACACUGUCUGGUAACGAUG---------------- 10322 0,-1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGa--------------- 827 0,-1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGaa-------------- 23 0,-1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGau-------------- 34 0,-1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGc--------------- 53 0,-1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGg--------------- 956 0,-1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGU--------------- 39697 0,0 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUa-------------- 334 0,0 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUaa------------- 59 0,0 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUau------------- 17 0,0 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUc-------------- 118 0,0 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUg-------------- 7 0,0 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUU-------------- 83515 0,1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUUa------------- 1412 0,1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUUaa------------ 15 0,1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUUau------------ 4 0,1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUUg------------- 49 0,1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUUu------------- 8764 0,1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUUuu------------ 51 0,1 -----------------------------------------------------UAACACUGUCUGGUAACGAUGUUC------------- 51 0,2 ------------------------------------------------------AACACUGUCUGGUAACGA------------------ 4 1,-3 ------------------------------------------------------AACACUGUCUGGUAACGAU----------------- 65 1,-2 ------------------------------------------------------AACACUGUCUGGUAACGAUa---------------- 18 1,-2 ------------------------------------------------------AACACUGUCUGGUAACGAUu---------------- 3 1,-2 ------------------------------------------------------AACACUGUCUGGUAACGAUG---------------- 459 1,-1 ------------------------------------------------------AACACUGUCUGGUAACGAUGa--------------- 27 1,-1 ------------------------------------------------------AACACUGUCUGGUAACGAUGg--------------- 8 1,-1 ------------------------------------------------------AACACUGUCUGGUAACGAUGU--------------- 2042 1,0 ------------------------------------------------------AACACUGUCUGGUAACGAUGUa-------------- 4 1,0 ------------------------------------------------------AACACUGUCUGGUAACGAUGUaa------------- 2 1,0 ------------------------------------------------------AACACUGUCUGGUAACGAUGUU-------------- 4384 1,1 ------------------------------------------------------AACACUGUCUGGUAACGAUGUUa------------- 210 1,1 ------------------------------------------------------AACACUGUCUGGUAACGAUGUUaa------------ 4 1,1 ------------------------------------------------------AACACUGUCUGGUAACGAUGUUu------------- 820 1,1 ------------------------------------------------------AACACUGUCUGGUAACGAUGUUuu------------ 7 1,1 ------------------------------------------------------AACACUGUCUGGUAACGAUGUUC------------- 11 1,2 -------------------------------------------------------ACACUGUCUGGUAACGAUG---------------- 13 2,-1 -------------------------------------------------------ACACUGUCUGGUAACGAUGU--------------- 104 2,0 -------------------------------------------------------ACACUGUCUGGUAACGAUGUU-------------- 277 2,1 -------------------------------------------------------ACACUGUCUGGUAACGAUGUUa------------- 4 2,1 -------------------------------------------------------ACACUGUCUGGUAACGAUGUUu------------- 27 2,1 >hsa-mir-200b mi:21-42;MA:57-78 Tumor ccagcucgggcagccguggcCAUCUUACUGGGCAGCAUUGGAuggagucaggucucUAAUACUGCCUGGUAAUGAUGAcggcggagcccugcacg --------------------CAUCUUACUGGGCAGCAUU-------------------------------------------------------- 8 0,-3 --------------------CAUCUUACUGGGCAGCAUUaa------------------------------------------------------ 2 0,-3 --------------------CAUCUUACUGGGCAGCAUUG------------------------------------------------------- 65 0,-2 --------------------CAUCUUACUGGGCAGCAUUGa------------------------------------------------------ 20 0,-2 --------------------CAUCUUACUGGGCAGCAUUGaa----------------------------------------------------- 2 0,-2 --------------------CAUCUUACUGGGCAGCAUUGu------------------------------------------------------ 6 0,-2 --------------------CAUCUUACUGGGCAGCAUUGG------------------------------------------------------ 565 0,-1 --------------------CAUCUUACUGGGCAGCAUUGGc----------------------------------------------------- 4 0,-1 --------------------CAUCUUACUGGGCAGCAUUGGg----------------------------------------------------- 2 0,-1 --------------------CAUCUUACUGGGCAGCAUUGGu----------------------------------------------------- 24 0,-1 --------------------CAUCUUACUGGGCAGCAUUGGA----------------------------------------------------- 1006 0,0 --------------------CAUCUUACUGGGCAGCAUUGGAa---------------------------------------------------- 78 0,0 --------------------CAUCUUACUGGGCAGCAUUGGAaa--------------------------------------------------- 6 0,0 --------------------CAUCUUACUGGGCAGCAUUGGAau--------------------------------------------------- 2 0,0 --------------------CAUCUUACUGGGCAGCAUUGGAU---------------------------------------------------- 21 0,1 ---------------------AUCUUACUGGGCAGCAUUG------------------------------------------------------- 4 1,-2 ---------------------AUCUUACUGGGCAGCAUUGG------------------------------------------------------ 60 1,-1 ---------------------AUCUUACUGGGCAGCAUUGGu----------------------------------------------------- 2 1,-1 ---------------------AUCUUACUGGGCAGCAUUGGA----------------------------------------------------- 286 1,0 ---------------------AUCUUACUGGGCAGCAUUGGAa---------------------------------------------------- 26 1,0 ---------------------AUCUUACUGGGCAGCAUUGGAaa--------------------------------------------------- 5 1,0 ---------------------AUCUUACUGGGCAGCAUUGGAU---------------------------------------------------- 6 1,1 ------------------------------------------------------UCUAAUACUGCCUGGUAAUGAUGA----------------- 2 -2,0 ------------------------------------------------------UCUAAUACUGCCUGGUAAUGAUGAC---------------- 8 -2,1 -------------------------------------------------------CUAAUACUGCCUGGUAAUGuu------------------- 2 -1,-4 -------------------------------------------------------CUAAUACUGCCUGGUAAUGA-------------------- 2 -1,-3 -------------------------------------------------------CUAAUACUGCCUGGUAAUGAa------------------- 2 -1,-3 -------------------------------------------------------CUAAUACUGCCUGGUAAUGAaa------------------ 2 -1,-3 -------------------------------------------------------CUAAUACUGCCUGGUAAUGAU------------------- 27 -1,-2 -------------------------------------------------------CUAAUACUGCCUGGUAAUGAUa------------------ 2 -1,-2 -------------------------------------------------------CUAAUACUGCCUGGUAAUGAUG------------------ 101 -1,-1 -------------------------------------------------------CUAAUACUGCCUGGUAAUGAUGA----------------- 145 -1,0 -------------------------------------------------------CUAAUACUGCCUGGUAAUGAUGAa---------------- 2 -1,0 -------------------------------------------------------CUAAUACUGCCUGGUAAUGAUGAC---------------- 117 -1,1 -------------------------------------------------------CUAAUACUGCCUGGUAAUGAUGACa--------------- 7 -1,1 -------------------------------------------------------CUAAUACUGCCUGGUAAUGAUGACu--------------- 26 -1,1 --------------------------------------------------------UAAUACUGCCUGGUAAUG--------------------- 593 0,-4 --------------------------------------------------------UAAUACUGCCUGGUAAUGu-------------------- 118 0,-4 --------------------------------------------------------UAAUACUGCCUGGUAAUGuu------------------- 7 0,-4 --------------------------------------------------------UAAUACUGCCUGGUAAUGA-------------------- 3505 0,-3 --------------------------------------------------------UAAUACUGCCUGGUAAUGAa------------------- 819 0,-3 --------------------------------------------------------UAAUACUGCCUGGUAAUGAaa------------------ 930 0,-3 --------------------------------------------------------UAAUACUGCCUGGUAAUGAau------------------ 57 0,-3 --------------------------------------------------------UAAUACUGCCUGGUAAUGAc------------------- 4 0,-3 --------------------------------------------------------UAAUACUGCCUGGUAAUGAg------------------- 21 0,-3 --------------------------------------------------------UAAUACUGCCUGGUAAUGAU------------------- 6686 0,-2 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUa------------------ 1651 0,-2 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUaa----------------- 307 0,-2 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUau----------------- 65 0,-2 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUc------------------ 6 0,-2 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUu------------------ 451 0,-2 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUuu----------------- 23 0,-2 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUG------------------ 22070 0,-1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGc----------------- 177 0,-1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGg----------------- 96 0,-1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGu----------------- 1994 0,-1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGuu---------------- 118 0,-1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGA----------------- 51165 0,0 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGAa---------------- 3066 0,0 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGAaa--------------- 430 0,0 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGAau--------------- 161 0,0 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGAg---------------- 108 0,0 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGAu---------------- 1043 0,0 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGAuu--------------- 96 0,0 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGAC---------------- 37403 0,1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGACa--------------- 5129 0,1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGACaa-------------- 10 0,1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGACau-------------- 2 0,1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGACc--------------- 172 0,1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGACu--------------- 7351 0,1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGACuu-------------- 11 0,1 --------------------------------------------------------UAAUACUGCCUGGUAAUGAUGACG--------------- 273 0,2 ---------------------------------------------------------AAUACUGCCUGGUAAUGA-------------------- 80 1,-3 ---------------------------------------------------------AAUACUGCCUGGUAAUGAa------------------- 22 1,-3 ---------------------------------------------------------AAUACUGCCUGGUAAUGAaa------------------ 32 1,-3 ---------------------------------------------------------AAUACUGCCUGGUAAUGAc------------------- 2 1,-3 ---------------------------------------------------------AAUACUGCCUGGUAAUGAU------------------- 254 1,-2 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUa------------------ 55 1,-2 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUaa----------------- 3 1,-2 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUu------------------ 13 1,-2 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUG------------------ 904 1,-1 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGu----------------- 53 1,-1 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGA----------------- 2307 1,0 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGAa---------------- 157 1,0 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGAaa--------------- 17 1,0 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGAau--------------- 13 1,0 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGAu---------------- 40 1,0 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGAuu--------------- 43 1,0 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGAC---------------- 2337 1,1 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGACa--------------- 1034 1,1 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGACau-------------- 2 1,1 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGACc--------------- 66 1,1 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGACu--------------- 4506 1,1 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGACuu-------------- 2 1,1 ---------------------------------------------------------AAUACUGCCUGGUAAUGAUGACG--------------- 26 1,2 ----------------------------------------------------------AUACUGCCUGGUAAUGAU------------------- 2 2,-2 ----------------------------------------------------------AUACUGCCUGGUAAUGAUa------------------ 2 2,-2 ----------------------------------------------------------AUACUGCCUGGUAAUGAUG------------------ 34 2,-1 ----------------------------------------------------------AUACUGCCUGGUAAUGAUGu----------------- 3 2,-1 ----------------------------------------------------------AUACUGCCUGGUAAUGAUGA----------------- 138 2,0 ----------------------------------------------------------AUACUGCCUGGUAAUGAUGAa---------------- 10 2,0 ----------------------------------------------------------AUACUGCCUGGUAAUGAUGAC---------------- 140 2,1 ----------------------------------------------------------AUACUGCCUGGUAAUGAUGACa--------------- 89 2,1 ----------------------------------------------------------AUACUGCCUGGUAAUGAUGACaa-------------- 3 2,1 ----------------------------------------------------------AUACUGCCUGGUAAUGAUGACau-------------- 3 2,1 ----------------------------------------------------------AUACUGCCUGGUAAUGAUGACu--------------- 405 2,1 ----------------------------------------------------------AUACUGCCUGGUAAUGAUGACuu-------------- 125 2,1 ----------------------------------------------------------AUACUGCCUGGUAAUGAUGACG--------------- 37 2,2 ----------------------------------------------------------AUACUGCCUGGUAAUGAUGACGG-------------- 36 2,3 >hsa-mir-200c mi:5-26;MA:44-66 Tumor cccuCGUCUUACCCAGCAGUGUUUGGgugcgguugggagucucUAAUACUGCCGGGUAAUGAUGGAgg ----CGUCUUACCCAGCAGUGUUUG------------------------------------------- 44 0,-1 ----CGUCUUACCCAGCAGUGUUUGG------------------------------------------ 331 0,0 ----CGUCUUACCCAGCAGUGUUUGGa----------------------------------------- 4 0,0 ----CGUCUUACCCAGCAGUGUUUGGu----------------------------------------- 9 0,0 ----CGUCUUACCCAGCAGUGUUUGGG----------------------------------------- 9 0,1 ----CGUCUUACCCAGCAGUGUUUGGGa---------------------------------------- 2 0,1 ----CGUCUUACCCAGCAGUGUUUGGGU---------------------------------------- 5 0,2 -----GUCUUACCCAGCAGUGUUUGG------------------------------------------ 14 1,0 -----GUCUUACCCAGCAGUGUUUGGG----------------------------------------- 2 1,1 -----------------------------------------UCUAAUACUGCCGGGUAAUGAUGGA-- 6 -2,0 ------------------------------------------CUAAUACUGCCGGGUAAUG------- 4 -1,-5 ------------------------------------------CUAAUACUGCCGGGUAAUGA------ 65 -1,-4 ------------------------------------------CUAAUACUGCCGGGUAAUGAa----- 4 -1,-4 ------------------------------------------CUAAUACUGCCGGGUAAUGAaa---- 5 -1,-4 ------------------------------------------CUAAUACUGCCGGGUAAUGAU----- 541 -1,-3 ------------------------------------------CUAAUACUGCCGGGUAAUGAUa---- 40 -1,-3 ------------------------------------------CUAAUACUGCCGGGUAAUGAUG---- 1077 -1,-2 ------------------------------------------CUAAUACUGCCGGGUAAUGAUGa--- 11 -1,-2 ------------------------------------------CUAAUACUGCCGGGUAAUGAUGu--- 25 -1,-2 ------------------------------------------CUAAUACUGCCGGGUAAUGAUGG--- 682 -1,-1 ------------------------------------------CUAAUACUGCCGGGUAAUGAUGGu-- 56 -1,-1 ------------------------------------------CUAAUACUGCCGGGUAAUGAUGGA-- 492 -1,0 ------------------------------------------CUAAUACUGCCGGGUAAUGAUGGAa- 15 -1,0 ------------------------------------------CUAAUACUGCCGGGUAAUGAUGGAu- 21 -1,0 -------------------------------------------UAAUACUGCCGGGUAAUG------- 844 0,-5 -------------------------------------------UAAUACUGCCGGGUAAUGu------ 53 0,-5 -------------------------------------------UAAUACUGCCGGGUAAUGA------ 1113 0,-4 -------------------------------------------UAAUACUGCCGGGUAAUGAa----- 119 0,-4 -------------------------------------------UAAUACUGCCGGGUAAUGAaa---- 191 0,-4 -------------------------------------------UAAUACUGCCGGGUAAUGAau---- 12 0,-4 -------------------------------------------UAAUACUGCCGGGUAAUGAc----- 6 0,-4 -------------------------------------------UAAUACUGCCGGGUAAUGAg----- 5 0,-4 -------------------------------------------UAAUACUGCCGGGUAAUGAU----- 5510 0,-3 -------------------------------------------UAAUACUGCCGGGUAAUGAUa---- 765 0,-3 -------------------------------------------UAAUACUGCCGGGUAAUGAUaa--- 115 0,-3 -------------------------------------------UAAUACUGCCGGGUAAUGAUau--- 35 0,-3 -------------------------------------------UAAUACUGCCGGGUAAUGAUc---- 4 0,-3 -------------------------------------------UAAUACUGCCGGGUAAUGAUu---- 280 0,-3 -------------------------------------------UAAUACUGCCGGGUAAUGAUuu--- 4 0,-3 -------------------------------------------UAAUACUGCCGGGUAAUGAUG---- 12636 0,-2 -------------------------------------------UAAUACUGCCGGGUAAUGAUGa--- 1932 0,-2 -------------------------------------------UAAUACUGCCGGGUAAUGAUGaa-- 404 0,-2 -------------------------------------------UAAUACUGCCGGGUAAUGAUGau-- 31 0,-2 -------------------------------------------UAAUACUGCCGGGUAAUGAUGc--- 13 0,-2 -------------------------------------------UAAUACUGCCGGGUAAUGAUGu--- 1481 0,-2 -------------------------------------------UAAUACUGCCGGGUAAUGAUGuu-- 62 0,-2 -------------------------------------------UAAUACUGCCGGGUAAUGAUGG--- 45435 0,-1 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGc-- 639 0,-1 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGg-- 154 0,-1 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGu-- 8835 0,-1 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGuu- 818 0,-1 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGA-- 108538 0,0 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGAa- 12905 0,0 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGAaa 742 0,0 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGAau 722 0,0 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGAc- 172 0,0 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGAu- 6913 0,0 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGAuu 144 0,0 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGAG- 293 0,1 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGAGa 3 0,1 -------------------------------------------UAAUACUGCCGGGUAAUGAUGGAGu 6 0,1 --------------------------------------------AAUACUGCCGGGUAAUGA------ 27 1,-4 --------------------------------------------AAUACUGCCGGGUAAUGAa----- 2 1,-4 --------------------------------------------AAUACUGCCGGGUAAUGAaa---- 2 1,-4 --------------------------------------------AAUACUGCCGGGUAAUGAU----- 170 1,-3 --------------------------------------------AAUACUGCCGGGUAAUGAUa---- 13 1,-3 --------------------------------------------AAUACUGCCGGGUAAUGAUau--- 2 1,-3 --------------------------------------------AAUACUGCCGGGUAAUGAUu---- 2 1,-3 --------------------------------------------AAUACUGCCGGGUAAUGAUG---- 481 1,-2 --------------------------------------------AAUACUGCCGGGUAAUGAUGa--- 55 1,-2 --------------------------------------------AAUACUGCCGGGUAAUGAUGaa-- 4 1,-2 --------------------------------------------AAUACUGCCGGGUAAUGAUGu--- 42 1,-2 --------------------------------------------AAUACUGCCGGGUAAUGAUGG--- 1793 1,-1 --------------------------------------------AAUACUGCCGGGUAAUGAUGGc-- 9 1,-1 --------------------------------------------AAUACUGCCGGGUAAUGAUGGg-- 4 1,-1 --------------------------------------------AAUACUGCCGGGUAAUGAUGGu-- 383 1,-1 --------------------------------------------AAUACUGCCGGGUAAUGAUGGuu- 13 1,-1 --------------------------------------------AAUACUGCCGGGUAAUGAUGGA-- 4678 1,0 --------------------------------------------AAUACUGCCGGGUAAUGAUGGAa- 543 1,0 --------------------------------------------AAUACUGCCGGGUAAUGAUGGAaa 9 1,0 --------------------------------------------AAUACUGCCGGGUAAUGAUGGAau 12 1,0 --------------------------------------------AAUACUGCCGGGUAAUGAUGGAc- 2 1,0 --------------------------------------------AAUACUGCCGGGUAAUGAUGGAu- 277 1,0 --------------------------------------------AAUACUGCCGGGUAAUGAUGGAG- 7 1,1 ---------------------------------------------AUACUGCCGGGUAAUGAUG---- 17 2,-2 ---------------------------------------------AUACUGCCGGGUAAUGAUGa--- 2 2,-2 ---------------------------------------------AUACUGCCGGGUAAUGAUGG--- 94 2,-1 ---------------------------------------------AUACUGCCGGGUAAUGAUGGu-- 4 2,-1 ---------------------------------------------AUACUGCCGGGUAAUGAUGGuu- 2 2,-1 ---------------------------------------------AUACUGCCGGGUAAUGAUGGA-- 268 2,0 ---------------------------------------------AUACUGCCGGGUAAUGAUGGAa- 20 2,0 ---------------------------------------------AUACUGCCGGGUAAUGAUGGAu- 7 2,0 >hsa-mir-202 mi:28-49;MA:64-83 Tumor cgccucagagccgcccgccguuccuuuUUCCUAUGCAUAUACUUCUUUGaggaucuggccuaaAGAGGUAUAGGGCAUGGGAAaacggggcggucggguccuccccagcg --------------------------UUUCCUAUGCAUAUACUUCUUU-------------------------------------------------------------- 2 -1,-1 ---------------------------UUCCUAUGCAUAUACUUCU---------------------------------------------------------------- 8 0,-3 ---------------------------UUCCUAUGCAUAUACUUCUU--------------------------------------------------------------- 18 0,-2 ---------------------------UUCCUAUGCAUAUACUUCUUU-------------------------------------------------------------- 88 0,-1 ---------------------------UUCCUAUGCAUAUACUUCUUUaa------------------------------------------------------------ 2 0,-1 ---------------------------UUCCUAUGCAUAUACUUCUUUGA------------------------------------------------------------ 2 0,1 >hsa-mir-203 3pM:65-86 Tumor guguuggggacucgcgcgcuggguccagugguucuuaacaguucaacaguucuguagcgcaauuGUGAAAUGUUUAGGACCACUAGacccggcgggcgcggcgacagcga --------------------------AGUGGUUCUUAACAGUUCA----------------------------------------------------------------- 15 --------------------------AGUGGUUCUUAACAGUUCAA---------------------------------------------------------------- 20 --------------------------AGUGGUUCUUAACAGUUCAAC--------------------------------------------------------------- 141 --------------------------AGUGGUUCUUAACAGUUCAACA-------------------------------------------------------------- 192 --------------------------AGUGGUUCUUAACAGUUCAACAG------------------------------------------------------------- 15 --------------------------AGUGGUUCUUAACAGUUCAACAGU------------------------------------------------------------ 7 --------------------------------------------------------------UUGUGAAAUGUUUAGGACCACU-------------------------- 13 -2,-2 --------------------------------------------------------------UUGUGAAAUGUUUAGGACCACUAaa----------------------- 2 -2,-1 ---------------------------------------------------------------UGUGAAAUGUUUAGGACCACU-------------------------- 148 -1,-2 ---------------------------------------------------------------UGUGAAAUGUUUAGGACCACUA------------------------- 53 -1,-1 ---------------------------------------------------------------UGUGAAAUGUUUAGGACCACUAa------------------------ 2 -1,-1 ---------------------------------------------------------------UGUGAAAUGUUUAGGACCACUAu------------------------ 22 -1,-1 ---------------------------------------------------------------UGUGAAAUGUUUAGGACCACUAG------------------------ 119 -1,0 ---------------------------------------------------------------UGUGAAAUGUUUAGGACCACUAGu----------------------- 27 -1,0 ----------------------------------------------------------------GUGAAAUGUUUAGGACCA---------------------------- 65 0,-4 ----------------------------------------------------------------GUGAAAUGUUUAGGACCAa--------------------------- 9 0,-4 ----------------------------------------------------------------GUGAAAUGUUUAGGACCAau-------------------------- 7 0,-4 ----------------------------------------------------------------GUGAAAUGUUUAGGACCAu--------------------------- 10 0,-4 ----------------------------------------------------------------GUGAAAUGUUUAGGACCAuu-------------------------- 5 0,-4 ----------------------------------------------------------------GUGAAAUGUUUAGGACCAC--------------------------- 179 0,-3 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACa-------------------------- 16 0,-3 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACaa------------------------- 2 0,-3 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACau------------------------- 2 0,-3 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACc-------------------------- 2 0,-3 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACU-------------------------- 4272 0,-2 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUg------------------------- 2 0,-2 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUu------------------------- 32 0,-2 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUuu------------------------ 6 0,-2 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUA------------------------- 1706 0,-1 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAa------------------------ 526 0,-1 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAaa----------------------- 54 0,-1 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAau----------------------- 10 0,-1 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAc------------------------ 26 0,-1 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAu------------------------ 1075 0,-1 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAuu----------------------- 34 0,-1 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAG------------------------ 14373 0,0 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAGc----------------------- 14 0,0 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAGg----------------------- 7 0,0 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAGu----------------------- 2087 0,0 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAGuu---------------------- 13 0,0 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAGA----------------------- 3073 0,1 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAGAa---------------------- 35 0,1 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAGAaa--------------------- 2 0,1 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAGAau--------------------- 2 0,1 ----------------------------------------------------------------GUGAAAUGUUUAGGACCACUAGAu---------------------- 4 0,1 -----------------------------------------------------------------UGAAAUGUUUAGGACCAC--------------------------- 4 1,-3 -----------------------------------------------------------------UGAAAUGUUUAGGACCACU-------------------------- 348 1,-2 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUu------------------------- 17 1,-2 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUuu------------------------ 16 1,-2 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUA------------------------- 224 1,-1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAa------------------------ 130 1,-1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAaa----------------------- 43 1,-1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAau----------------------- 12 1,-1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAc------------------------ 2 1,-1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAu------------------------ 247 1,-1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAuu----------------------- 15 1,-1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAG------------------------ 4945 1,0 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAGc----------------------- 10 1,0 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAGg----------------------- 3 1,0 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAGu----------------------- 3492 1,0 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAGuu---------------------- 152 1,0 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAGA----------------------- 1933 1,1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAGAa---------------------- 115 1,1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAGAaa--------------------- 14 1,1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAGAau--------------------- 5 1,1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAGAg---------------------- 6 1,1 -----------------------------------------------------------------UGAAAUGUUUAGGACCACUAGAu---------------------- 34 1,1 ------------------------------------------------------------------GAAAUGUUUAGGACCACU-------------------------- 4 2,-2 ------------------------------------------------------------------GAAAUGUUUAGGACCACUA------------------------- 4 2,-1 ------------------------------------------------------------------GAAAUGUUUAGGACCACUAa------------------------ 2 2,-1 ------------------------------------------------------------------GAAAUGUUUAGGACCACUAu------------------------ 5 2,-1 ------------------------------------------------------------------GAAAUGUUUAGGACCACUAG------------------------ 119 2,0 ------------------------------------------------------------------GAAAUGUUUAGGACCACUAGu----------------------- 84 2,0 ------------------------------------------------------------------GAAAUGUUUAGGACCACUAGuu---------------------- 2 2,0 ------------------------------------------------------------------GAAAUGUUUAGGACCACUAGA----------------------- 45 2,1 >hsa-mir-204 5pM:33-54 Tumor ggcuacagucuuucuucaugugacucguggacUUCCCUUUGUCAUCCUAUGCCUgagaauauaugaaggaggcugggaaggcaaagggacguucaauugucaucacuggc --------------------------------UUCCCUUUGUCAUCCUAUG----------------------------------------------------------- 2 0,-3 --------------------------------UUCCCUUUGUCAUCCUAUGC---------------------------------------------------------- 6 0,-2 --------------------------------UUCCCUUUGUCAUCCUAUGCC--------------------------------------------------------- 8 0,-1 --------------------------------UUCCCUUUGUCAUCCUAUGCCU-------------------------------------------------------- 86 0,0 --------------------------------UUCCCUUUGUCAUCCUAUGCCUu------------------------------------------------------- 5 0,0 --------------------------------UUCCCUUUGUCAUCCUAUGCCUG------------------------------------------------------- 3 0,1 --------------------------------UUCCCUUUGUCAUCCUAUGCCUGu------------------------------------------------------ 8 0,1 --------------------------------UUCCCUUUGUCAUCCUAUGCCUGA------------------------------------------------------ 2 0,2 >hsa-mir-205 MA:34-55;mi:71-91 Tumor aaagauccucagacaauccaugugcuucucuugUCCUUCAUUCCACCGGAGUCUGucucauacccaaccaGAUUUCAGUGGAGUGAAGUUCaggaggcauggagcugaca ---------------------------------UCCUUCAUUCCACCGGAG----------------------------------------------------------- 615 0,-4 ---------------------------------UCCUUCAUUCCACCGGAGa---------------------------------------------------------- 108 0,-4 ---------------------------------UCCUUCAUUCCACCGGAGaa--------------------------------------------------------- 4 0,-4 ---------------------------------UCCUUCAUUCCACCGGAGU---------------------------------------------------------- 2278 0,-3 ---------------------------------UCCUUCAUUCCACCGGAGUa--------------------------------------------------------- 18 0,-3 ---------------------------------UCCUUCAUUCCACCGGAGUaa-------------------------------------------------------- 27 0,-3 ---------------------------------UCCUUCAUUCCACCGGAGUau-------------------------------------------------------- 31 0,-3 ---------------------------------UCCUUCAUUCCACCGGAGUu--------------------------------------------------------- 11 0,-3 ---------------------------------UCCUUCAUUCCACCGGAGUuu-------------------------------------------------------- 16 0,-3 ---------------------------------UCCUUCAUUCCACCGGAGUC--------------------------------------------------------- 2122 0,-2 ---------------------------------UCCUUCAUUCCACCGGAGUCa-------------------------------------------------------- 364 0,-2 ---------------------------------UCCUUCAUUCCACCGGAGUCaa------------------------------------------------------- 6 0,-2 ---------------------------------UCCUUCAUUCCACCGGAGUCc-------------------------------------------------------- 38 0,-2 ---------------------------------UCCUUCAUUCCACCGGAGUCg-------------------------------------------------------- 12 0,-2 ---------------------------------UCCUUCAUUCCACCGGAGUCU-------------------------------------------------------- 26280 0,-1 ---------------------------------UCCUUCAUUCCACCGGAGUCUa------------------------------------------------------- 158 0,-1 ---------------------------------UCCUUCAUUCCACCGGAGUCUaa------------------------------------------------------ 20 0,-1 ---------------------------------UCCUUCAUUCCACCGGAGUCUau------------------------------------------------------ 99 0,-1 ---------------------------------UCCUUCAUUCCACCGGAGUCUc------------------------------------------------------- 17 0,-1 ---------------------------------UCCUUCAUUCCACCGGAGUCUu------------------------------------------------------- 425 0,-1 ---------------------------------UCCUUCAUUCCACCGGAGUCUuu------------------------------------------------------ 117 0,-1 ---------------------------------UCCUUCAUUCCACCGGAGUCUG------------------------------------------------------- 46169 0,0 ---------------------------------UCCUUCAUUCCACCGGAGUCUGa------------------------------------------------------ 13383 0,0 ---------------------------------UCCUUCAUUCCACCGGAGUCUGaa----------------------------------------------------- 137 0,0 ---------------------------------UCCUUCAUUCCACCGGAGUCUGau----------------------------------------------------- 140 0,0 ---------------------------------UCCUUCAUUCCACCGGAGUCUGc------------------------------------------------------ 312 0,0 ---------------------------------UCCUUCAUUCCACCGGAGUCUGg------------------------------------------------------ 142 0,0 ---------------------------------UCCUUCAUUCCACCGGAGUCUGU------------------------------------------------------ 40461 0,1 ---------------------------------UCCUUCAUUCCACCGGAGUCUGUa----------------------------------------------------- 634 0,1 ---------------------------------UCCUUCAUUCCACCGGAGUCUGUaa---------------------------------------------------- 65 0,1 ---------------------------------UCCUUCAUUCCACCGGAGUCUGUau---------------------------------------------------- 108 0,1 ---------------------------------UCCUUCAUUCCACCGGAGUCUGUg----------------------------------------------------- 8 0,1 ---------------------------------UCCUUCAUUCCACCGGAGUCUGUu----------------------------------------------------- 1958 0,1 ---------------------------------UCCUUCAUUCCACCGGAGUCUGUuu---------------------------------------------------- 265 0,1 ---------------------------------UCCUUCAUUCCACCGGAGUCUGUC----------------------------------------------------- 14 0,2 ---------------------------------UCCUUCAUUCCACCGGAGUCUGUCU---------------------------------------------------- 5 0,3 ----------------------------------CCUUCAUUCCACCGGAGUC--------------------------------------------------------- 2 1,-2 ----------------------------------CCUUCAUUCCACCGGAGUCU-------------------------------------------------------- 10 1,-1 ----------------------------------CCUUCAUUCCACCGGAGUCUG------------------------------------------------------- 24 1,0 ----------------------------------CCUUCAUUCCACCGGAGUCUGa------------------------------------------------------ 4 1,0 ----------------------------------CCUUCAUUCCACCGGAGUCUGU------------------------------------------------------ 30 1,1 ----------------------------------CCUUCAUUCCACCGGAGUCUGUu----------------------------------------------------- 2 1,1 -----------------------------------CUUCAUUCCACCGGAGUC--------------------------------------------------------- 7 2,-2 -----------------------------------CUUCAUUCCACCGGAGUCU-------------------------------------------------------- 153 2,-1 -----------------------------------CUUCAUUCCACCGGAGUCUG------------------------------------------------------- 352 2,0 -----------------------------------CUUCAUUCCACCGGAGUCUGa------------------------------------------------------ 61 2,0 -----------------------------------CUUCAUUCCACCGGAGUCUGau----------------------------------------------------- 2 2,0 -----------------------------------CUUCAUUCCACCGGAGUCUGU------------------------------------------------------ 251 2,1 -----------------------------------CUUCAUUCCACCGGAGUCUGUu----------------------------------------------------- 9 2,1 ----------------------------------------------------------------------GAUUUCAGUGGAGUGAAGUU-------------------- 21 0,-1 ----------------------------------------------------------------------GAUUUCAGUGGAGUGAAGUUC------------------- 172 0,0 ----------------------------------------------------------------------GAUUUCAGUGGAGUGAAGUUCu------------------ 2 0,0 ----------------------------------------------------------------------GAUUUCAGUGGAGUGAAGUUCA------------------ 169 0,1 -----------------------------------------------------------------------AUUUCAGUGGAGUGAAGUUC------------------- 14 1,0 -----------------------------------------------------------------------AUUUCAGUGGAGUGAAGUUCA------------------ 13 1,1 -----------------------------------------------------------------------AUUUCAGUGGAGUGAAGUUCAa----------------- 2 1,1 ------------------------------------------------------------------------UUUCAGUGGAGUGAAGUUCA------------------ 4 2,1 >hsa-mir-208a 3pM:44-65 Tumor ugacgggcgagcuuuuggcccggguuauaccugaugcucacguAUAAGACGAGCAAAAAGCUUGUugguca -------------------------------------------AUAAGACGAGCAAAAAGCUUGU------ 2 0,0 >hsa-mir-208b 3pM:46-67 Tumor ccucucagggaagcuuuuugcucgaauuauguuucugauccgaauAUAAGACGAACAAAAGGUUUGUcugagggcag ---------------------------------------------AUAAGACGAACAAAAGGUUUGU---------- 2 0,0 >hsa-mir-20a MA:8-30;mi:44-65 Tumor guagcacUAAAGUGCUUAUAGUGCAGGUAGuguuuaguuaucuACUGCAUUAUGAGCACUUAAAGuacugc ------CUAAAGUGCUUAUAGUGCAGG-------------------------------------------- 2 -1,-3 ------CUAAAGUGCUUAUAGUGCAGGa------------------------------------------- 2 -1,-3 ------CUAAAGUGCUUAUAGUGCAGGU------------------------------------------- 10 -1,-2 ------CUAAAGUGCUUAUAGUGCAGGUA------------------------------------------ 23 -1,-1 ------CUAAAGUGCUUAUAGUGCAGGUAa----------------------------------------- 14 -1,-1 ------CUAAAGUGCUUAUAGUGCAGGUAu----------------------------------------- 8 -1,-1 ------CUAAAGUGCUUAUAGUGCAGGUAG----------------------------------------- 71 -1,0 ------CUAAAGUGCUUAUAGUGCAGGUAGa---------------------------------------- 2 -1,0 ------CUAAAGUGCUUAUAGUGCAGGUAGU---------------------------------------- 4 -1,1 -------UAAAGUGCUUAUAGUGCA---------------------------------------------- 161 0,-5 -------UAAAGUGCUUAUAGUGCAa--------------------------------------------- 7 0,-5 -------UAAAGUGCUUAUAGUGCAaa-------------------------------------------- 3 0,-5 -------UAAAGUGCUUAUAGUGCAG--------------------------------------------- 304 0,-4 -------UAAAGUGCUUAUAGUGCAGa-------------------------------------------- 39 0,-4 -------UAAAGUGCUUAUAGUGCAGaa------------------------------------------- 20 0,-4 -------UAAAGUGCUUAUAGUGCAGau------------------------------------------- 2 0,-4 -------UAAAGUGCUUAUAGUGCAGu-------------------------------------------- 20 0,-4 -------UAAAGUGCUUAUAGUGCAGuu------------------------------------------- 11 0,-4 -------UAAAGUGCUUAUAGUGCAGG-------------------------------------------- 1348 0,-3 -------UAAAGUGCUUAUAGUGCAGGa------------------------------------------- 455 0,-3 -------UAAAGUGCUUAUAGUGCAGGaa------------------------------------------ 203 0,-3 -------UAAAGUGCUUAUAGUGCAGGau------------------------------------------ 46 0,-3 -------UAAAGUGCUUAUAGUGCAGGc------------------------------------------- 13 0,-3 -------UAAAGUGCUUAUAGUGCAGGg------------------------------------------- 7 0,-3 -------UAAAGUGCUUAUAGUGCAGGU------------------------------------------- 4118 0,-2 -------UAAAGUGCUUAUAGUGCAGGUc------------------------------------------ 21 0,-2 -------UAAAGUGCUUAUAGUGCAGGUg------------------------------------------ 14 0,-2 -------UAAAGUGCUUAUAGUGCAGGUu------------------------------------------ 271 0,-2 -------UAAAGUGCUUAUAGUGCAGGUuu----------------------------------------- 77 0,-2 -------UAAAGUGCUUAUAGUGCAGGUA------------------------------------------ 10209 0,-1 -------UAAAGUGCUUAUAGUGCAGGUAa----------------------------------------- 3123 0,-1 -------UAAAGUGCUUAUAGUGCAGGUAaa---------------------------------------- 114 0,-1 -------UAAAGUGCUUAUAGUGCAGGUAau---------------------------------------- 68 0,-1 -------UAAAGUGCUUAUAGUGCAGGUAc----------------------------------------- 71 0,-1 -------UAAAGUGCUUAUAGUGCAGGUAu----------------------------------------- 3047 0,-1 -------UAAAGUGCUUAUAGUGCAGGUAuu---------------------------------------- 118 0,-1 -------UAAAGUGCUUAUAGUGCAGGUAG----------------------------------------- 30361 0,0 -------UAAAGUGCUUAUAGUGCAGGUAGa---------------------------------------- 2670 0,0 -------UAAAGUGCUUAUAGUGCAGGUAGaa--------------------------------------- 167 0,0 -------UAAAGUGCUUAUAGUGCAGGUAGau--------------------------------------- 31 0,0 -------UAAAGUGCUUAUAGUGCAGGUAGc---------------------------------------- 23 0,0 -------UAAAGUGCUUAUAGUGCAGGUAGg---------------------------------------- 12 0,0 -------UAAAGUGCUUAUAGUGCAGGUAGU---------------------------------------- 2877 0,1 -------UAAAGUGCUUAUAGUGCAGGUAGUa--------------------------------------- 19 0,1 -------UAAAGUGCUUAUAGUGCAGGUAGUc--------------------------------------- 2 0,1 -------UAAAGUGCUUAUAGUGCAGGUAGUu--------------------------------------- 33 0,1 --------AAAGUGCUUAUAGUGCAGG-------------------------------------------- 27 1,-3 --------AAAGUGCUUAUAGUGCAGGa------------------------------------------- 8 1,-3 --------AAAGUGCUUAUAGUGCAGGaa------------------------------------------ 8 1,-3 --------AAAGUGCUUAUAGUGCAGGau------------------------------------------ 2 1,-3 --------AAAGUGCUUAUAGUGCAGGc------------------------------------------- 2 1,-3 --------AAAGUGCUUAUAGUGCAGGU------------------------------------------- 114 1,-2 --------AAAGUGCUUAUAGUGCAGGUu------------------------------------------ 4 1,-2 --------AAAGUGCUUAUAGUGCAGGUA------------------------------------------ 313 1,-1 --------AAAGUGCUUAUAGUGCAGGUAa----------------------------------------- 105 1,-1 --------AAAGUGCUUAUAGUGCAGGUAu----------------------------------------- 72 1,-1 --------AAAGUGCUUAUAGUGCAGGUAG----------------------------------------- 1040 1,0 --------AAAGUGCUUAUAGUGCAGGUAGa---------------------------------------- 90 1,0 --------AAAGUGCUUAUAGUGCAGGUAGaa--------------------------------------- 2 1,0 --------AAAGUGCUUAUAGUGCAGGUAGU---------------------------------------- 64 1,1 ---------AAGUGCUUAUAGUGCAGGU------------------------------------------- 2 2,-2 ---------AAGUGCUUAUAGUGCAGGUA------------------------------------------ 14 2,-1 ---------AAGUGCUUAUAGUGCAGGUAa----------------------------------------- 4 2,-1 ---------AAGUGCUUAUAGUGCAGGUAG----------------------------------------- 65 2,0 ---------AAGUGCUUAUAGUGCAGGUAGU---------------------------------------- 2 2,1 -------------------------------------------ACUGCAUUAUGAGCACUU---------- 8 0,-4 -------------------------------------------ACUGCAUUAUGAGCACUUu--------- 3 0,-4 -------------------------------------------ACUGCAUUAUGAGCACUUA--------- 41 0,-3 -------------------------------------------ACUGCAUUAUGAGCACUUAA-------- 214 0,-2 -------------------------------------------ACUGCAUUAUGAGCACUUAAA------- 271 0,-1 -------------------------------------------ACUGCAUUAUGAGCACUUAAAa------ 24 0,-1 -------------------------------------------ACUGCAUUAUGAGCACUUAAAuu----- 4 0,-1 -------------------------------------------ACUGCAUUAUGAGCACUUAAAG------ 559 0,0 -------------------------------------------ACUGCAUUAUGAGCACUUAAAGa----- 69 0,0 -------------------------------------------ACUGCAUUAUGAGCACUUAAAGc----- 4 0,0 -------------------------------------------ACUGCAUUAUGAGCACUUAAAGg----- 3 0,0 -------------------------------------------ACUGCAUUAUGAGCACUUAAAGU----- 1879 0,1 -------------------------------------------ACUGCAUUAUGAGCACUUAAAGUu---- 8 0,1 -------------------------------------------ACUGCAUUAUGAGCACUUAAAGUA---- 11 0,2 --------------------------------------------CUGCAUUAUGAGCACUUA--------- 2 1,-3 --------------------------------------------CUGCAUUAUGAGCACUUAA-------- 2 1,-2 --------------------------------------------CUGCAUUAUGAGCACUUAAA------- 7 1,-1 --------------------------------------------CUGCAUUAUGAGCACUUAAAG------ 28 1,0 --------------------------------------------CUGCAUUAUGAGCACUUAAAGa----- 7 1,0 --------------------------------------------CUGCAUUAUGAGCACUUAAAGaa---- 2 1,0 --------------------------------------------CUGCAUUAUGAGCACUUAAAGU----- 322 1,1 --------------------------------------------CUGCAUUAUGAGCACUUAAAGUu---- 4 1,1 --------------------------------------------CUGCAUUAUGAGCACUUAAAGUA---- 3 1,2 ---------------------------------------------UGCAUUAUGAGCACUUAAAG------ 2 2,0 ---------------------------------------------UGCAUUAUGAGCACUUAAAGU----- 5 2,1 >hsa-mir-20b MA:6-28;mi:44-65 Tumor aguacCAAAGUGCUCAUAGUGCAGGUAGuuuuggcaugacucuACUGUAGUAUGGGCACUUCCAGuacu -----CAAAGUGCUCAUAGUGCA---------------------------------------------- 4 0,-5 -----CAAAGUGCUCAUAGUGCAG--------------------------------------------- 21 0,-4 -----CAAAGUGCUCAUAGUGCAGG-------------------------------------------- 42 0,-3 -----CAAAGUGCUCAUAGUGCAGGU------------------------------------------- 291 0,-2 -----CAAAGUGCUCAUAGUGCAGGUu------------------------------------------ 3 0,-2 -----CAAAGUGCUCAUAGUGCAGGUuu----------------------------------------- 3 0,-2 -----CAAAGUGCUCAUAGUGCAGGUA------------------------------------------ 568 0,-1 -----CAAAGUGCUCAUAGUGCAGGUAa----------------------------------------- 254 0,-1 -----CAAAGUGCUCAUAGUGCAGGUAaa---------------------------------------- 9 0,-1 -----CAAAGUGCUCAUAGUGCAGGUAau---------------------------------------- 9 0,-1 -----CAAAGUGCUCAUAGUGCAGGUAu----------------------------------------- 357 0,-1 -----CAAAGUGCUCAUAGUGCAGGUAuu---------------------------------------- 6 0,-1 -----CAAAGUGCUCAUAGUGCAGGUAG----------------------------------------- 3570 0,0 -----CAAAGUGCUCAUAGUGCAGGUAGa---------------------------------------- 234 0,0 -----CAAAGUGCUCAUAGUGCAGGUAGaa--------------------------------------- 8 0,0 -----CAAAGUGCUCAUAGUGCAGGUAGau--------------------------------------- 5 0,0 -----CAAAGUGCUCAUAGUGCAGGUAGU---------------------------------------- 417 0,1 -----CAAAGUGCUCAUAGUGCAGGUAGUa--------------------------------------- 5 0,1 -----CAAAGUGCUCAUAGUGCAGGUAGUU--------------------------------------- 2 0,2 ------AAAGUGCUCAUAGUGCAGGU------------------------------------------- 4 1,-2 ------AAAGUGCUCAUAGUGCAGGUA------------------------------------------ 10 1,-1 ------AAAGUGCUCAUAGUGCAGGUAa----------------------------------------- 2 1,-1 ------AAAGUGCUCAUAGUGCAGGUAu----------------------------------------- 6 1,-1 ------AAAGUGCUCAUAGUGCAGGUAG----------------------------------------- 124 1,0 ------AAAGUGCUCAUAGUGCAGGUAGU---------------------------------------- 6 1,1 -------AAGUGCUCAUAGUGCAGGUAG----------------------------------------- 2 2,0 -------------------------------------------ACUGUAGUAUGGGCACUUC------- 4 0,-3 -------------------------------------------ACUGUAGUAUGGGCACUUCC------ 8 0,-2 -------------------------------------------ACUGUAGUAUGGGCACUUCCA----- 17 0,-1 -------------------------------------------ACUGUAGUAUGGGCACUUCCAG---- 13 0,0 -------------------------------------------ACUGUAGUAUGGGCACUUCCAGU--- 35 0,1 >hsa-mir-21 MA:8-29;mi:46-66 Tumor ugucgggUAGCUUAUCAGACUGAUGUUGAcuguugaaucucauggCAACACCAGUCGAUGGGCUGUcugaca ------GUAGCUUAUCAGACUGAU------------------------------------------------ 8 -1,-5 ------GUAGCUUAUCAGACUGAUG----------------------------------------------- 17 -1,-4 ------GUAGCUUAUCAGACUGAUGU---------------------------------------------- 16 -1,-3 ------GUAGCUUAUCAGACUGAUGUU--------------------------------------------- 257 -1,-2 ------GUAGCUUAUCAGACUGAUGUUa-------------------------------------------- 18 -1,-2 ------GUAGCUUAUCAGACUGAUGUUaa------------------------------------------- 5 -1,-2 ------GUAGCUUAUCAGACUGAUGUUu-------------------------------------------- 2 -1,-2 ------GUAGCUUAUCAGACUGAUGUUG-------------------------------------------- 3860 -1,-1 ------GUAGCUUAUCAGACUGAUGUUGc------------------------------------------- 7 -1,-1 ------GUAGCUUAUCAGACUGAUGUUGg------------------------------------------- 4 -1,-1 ------GUAGCUUAUCAGACUGAUGUUGu------------------------------------------- 15 -1,-1 ------GUAGCUUAUCAGACUGAUGUUGA------------------------------------------- 5778 -1,0 ------GUAGCUUAUCAGACUGAUGUUGAa------------------------------------------ 41 -1,0 ------GUAGCUUAUCAGACUGAUGUUGAu------------------------------------------ 4 -1,0 ------GUAGCUUAUCAGACUGAUGUUGAC------------------------------------------ 1680 -1,1 ------GUAGCUUAUCAGACUGAUGUUGACa----------------------------------------- 20 -1,1 ------GUAGCUUAUCAGACUGAUGUUGACU----------------------------------------- 90 -1,2 -------UAGCUUAUCAGACUGAUG----------------------------------------------- 43817 0,-4 -------UAGCUUAUCAGACUGAUGa---------------------------------------------- 1261 0,-4 -------UAGCUUAUCAGACUGAUGaa--------------------------------------------- 374 0,-4 -------UAGCUUAUCAGACUGAUGau--------------------------------------------- 23 0,-4 -------UAGCUUAUCAGACUGAUGc---------------------------------------------- 10 0,-4 -------UAGCUUAUCAGACUGAUGg---------------------------------------------- 5 0,-4 -------UAGCUUAUCAGACUGAUGU---------------------------------------------- 38475 0,-3 -------UAGCUUAUCAGACUGAUGUa--------------------------------------------- 1182 0,-3 -------UAGCUUAUCAGACUGAUGUaa-------------------------------------------- 1019 0,-3 -------UAGCUUAUCAGACUGAUGUau-------------------------------------------- 4 0,-3 -------UAGCUUAUCAGACUGAUGUc--------------------------------------------- 104 0,-3 -------UAGCUUAUCAGACUGAUGUg--------------------------------------------- 63 0,-3 -------UAGCUUAUCAGACUGAUGUU--------------------------------------------- 140916 0,-2 -------UAGCUUAUCAGACUGAUGUUa-------------------------------------------- 7716 0,-2 -------UAGCUUAUCAGACUGAUGUUaa------------------------------------------- 12839 0,-2 -------UAGCUUAUCAGACUGAUGUUau------------------------------------------- 22 0,-2 -------UAGCUUAUCAGACUGAUGUUc-------------------------------------------- 403 0,-2 -------UAGCUUAUCAGACUGAUGUUu-------------------------------------------- 3538 0,-2 -------UAGCUUAUCAGACUGAUGUUuu------------------------------------------- 304 0,-2 -------UAGCUUAUCAGACUGAUGUUG-------------------------------------------- 966043 0,-1 -------UAGCUUAUCAGACUGAUGUUGc------------------------------------------- 23328 0,-1 -------UAGCUUAUCAGACUGAUGUUGg------------------------------------------- 7313 0,-1 -------UAGCUUAUCAGACUGAUGUUGu------------------------------------------- 10513 0,-1 -------UAGCUUAUCAGACUGAUGUUGuu------------------------------------------ 547 0,-1 -------UAGCUUAUCAGACUGAUGUUGA------------------------------------------- 5905578 0,0 -------UAGCUUAUCAGACUGAUGUUGAa------------------------------------------ 208513 0,0 -------UAGCUUAUCAGACUGAUGUUGAaa----------------------------------------- 14376 0,0 -------UAGCUUAUCAGACUGAUGUUGAau----------------------------------------- 1348 0,0 -------UAGCUUAUCAGACUGAUGUUGAg------------------------------------------ 4120 0,0 -------UAGCUUAUCAGACUGAUGUUGAu------------------------------------------ 30694 0,0 -------UAGCUUAUCAGACUGAUGUUGAuu----------------------------------------- 1188 0,0 -------UAGCUUAUCAGACUGAUGUUGAC------------------------------------------ 3983168 0,1 -------UAGCUUAUCAGACUGAUGUUGACa----------------------------------------- 230231 0,1 -------UAGCUUAUCAGACUGAUGUUGACaa---------------------------------------- 849 0,1 -------UAGCUUAUCAGACUGAUGUUGACau---------------------------------------- 172 0,1 -------UAGCUUAUCAGACUGAUGUUGACc----------------------------------------- 15002 0,1 -------UAGCUUAUCAGACUGAUGUUGACg----------------------------------------- 14155 0,1 -------UAGCUUAUCAGACUGAUGUUGACU----------------------------------------- 132799 0,2 -------UAGCUUAUCAGACUGAUGUUGACUa---------------------------------------- 44 0,2 -------UAGCUUAUCAGACUGAUGUUGACUu---------------------------------------- 185 0,2 -------UAGCUUAUCAGACUGAUGUUGACUG---------------------------------------- 47 0,3 --------AGCUUAUCAGACUGAUGU---------------------------------------------- 1353 1,-3 --------AGCUUAUCAGACUGAUGUa--------------------------------------------- 24 1,-3 --------AGCUUAUCAGACUGAUGUaa-------------------------------------------- 27 1,-3 --------AGCUUAUCAGACUGAUGUU--------------------------------------------- 5763 1,-2 --------AGCUUAUCAGACUGAUGUUa-------------------------------------------- 329 1,-2 --------AGCUUAUCAGACUGAUGUUaa------------------------------------------- 481 1,-2 --------AGCUUAUCAGACUGAUGUUc-------------------------------------------- 10 1,-2 --------AGCUUAUCAGACUGAUGUUu-------------------------------------------- 178 1,-2 --------AGCUUAUCAGACUGAUGUUG-------------------------------------------- 39383 1,-1 --------AGCUUAUCAGACUGAUGUUGc------------------------------------------- 626 1,-1 --------AGCUUAUCAGACUGAUGUUGg------------------------------------------- 312 1,-1 --------AGCUUAUCAGACUGAUGUUGu------------------------------------------- 340 1,-1 --------AGCUUAUCAGACUGAUGUUGuu------------------------------------------ 9 1,-1 --------AGCUUAUCAGACUGAUGUUGA------------------------------------------- 229492 1,0 --------AGCUUAUCAGACUGAUGUUGAa------------------------------------------ 8562 1,0 --------AGCUUAUCAGACUGAUGUUGAaa----------------------------------------- 588 1,0 --------AGCUUAUCAGACUGAUGUUGAau----------------------------------------- 40 1,0 --------AGCUUAUCAGACUGAUGUUGAg------------------------------------------ 136 1,0 --------AGCUUAUCAGACUGAUGUUGAu------------------------------------------ 809 1,0 --------AGCUUAUCAGACUGAUGUUGAuu----------------------------------------- 4 1,0 --------AGCUUAUCAGACUGAUGUUGAC------------------------------------------ 164172 1,1 --------AGCUUAUCAGACUGAUGUUGACa----------------------------------------- 10390 1,1 --------AGCUUAUCAGACUGAUGUUGACaa---------------------------------------- 20 1,1 --------AGCUUAUCAGACUGAUGUUGACau---------------------------------------- 2 1,1 --------AGCUUAUCAGACUGAUGUUGACc----------------------------------------- 640 1,1 --------AGCUUAUCAGACUGAUGUUGACg----------------------------------------- 602 1,1 --------AGCUUAUCAGACUGAUGUUGACU----------------------------------------- 6029 1,2 --------AGCUUAUCAGACUGAUGUUGACUu---------------------------------------- 8 1,2 ---------GCUUAUCAGACUGAUGUU--------------------------------------------- 308 2,-2 ---------GCUUAUCAGACUGAUGUUa-------------------------------------------- 7 2,-2 ---------GCUUAUCAGACUGAUGUUaa------------------------------------------- 16 2,-2 ---------GCUUAUCAGACUGAUGUUu-------------------------------------------- 2 2,-2 ---------GCUUAUCAGACUGAUGUUG-------------------------------------------- 2303 2,-1 ---------GCUUAUCAGACUGAUGUUGc------------------------------------------- 5 2,-1 ---------GCUUAUCAGACUGAUGUUGg------------------------------------------- 6 2,-1 ---------GCUUAUCAGACUGAUGUUGu------------------------------------------- 2 2,-1 ---------GCUUAUCAGACUGAUGUUGA------------------------------------------- 15864 2,0 ---------GCUUAUCAGACUGAUGUUGAa------------------------------------------ 623 2,0 ---------GCUUAUCAGACUGAUGUUGAaa----------------------------------------- 11 2,0 ---------GCUUAUCAGACUGAUGUUGAg------------------------------------------ 2 2,0 ---------GCUUAUCAGACUGAUGUUGAu------------------------------------------ 23 2,0 ---------GCUUAUCAGACUGAUGUUGAC------------------------------------------ 11993 2,1 ---------GCUUAUCAGACUGAUGUUGACa----------------------------------------- 672 2,1 ---------GCUUAUCAGACUGAUGUUGACc----------------------------------------- 20 2,1 ---------GCUUAUCAGACUGAUGUUGACg----------------------------------------- 31 2,1 ---------GCUUAUCAGACUGAUGUUGACU----------------------------------------- 383 2,2 --------------------------------------------GCAACACCAGUCGAUGGGCUGUC----- 2 -1,1 ---------------------------------------------CAACACCAGUCGAUGGGC--------- 25 0,-3 ---------------------------------------------CAACACCAGUCGAUGGGCau------- 2 0,-3 ---------------------------------------------CAACACCAGUCGAUGGGCU-------- 155 0,-2 ---------------------------------------------CAACACCAGUCGAUGGGCUa------- 2 0,-2 ---------------------------------------------CAACACCAGUCGAUGGGCUaa------ 10 0,-2 ---------------------------------------------CAACACCAGUCGAUGGGCUau------ 33 0,-2 ---------------------------------------------CAACACCAGUCGAUGGGCUu------- 28 0,-2 ---------------------------------------------CAACACCAGUCGAUGGGCUuu------ 6 0,-2 ---------------------------------------------CAACACCAGUCGAUGGGCUG------- 538 0,-1 ---------------------------------------------CAACACCAGUCGAUGGGCUGa------ 187 0,-1 ---------------------------------------------CAACACCAGUCGAUGGGCUGaa----- 31 0,-1 ---------------------------------------------CAACACCAGUCGAUGGGCUGau----- 12 0,-1 ---------------------------------------------CAACACCAGUCGAUGGGCUGc------ 18 0,-1 ---------------------------------------------CAACACCAGUCGAUGGGCUGg------ 42 0,-1 ---------------------------------------------CAACACCAGUCGAUGGGCUGU------ 12259 0,0 ---------------------------------------------CAACACCAGUCGAUGGGCUGUa----- 340 0,0 ---------------------------------------------CAACACCAGUCGAUGGGCUGUaa---- 848 0,0 ---------------------------------------------CAACACCAGUCGAUGGGCUGUau---- 320 0,0 ---------------------------------------------CAACACCAGUCGAUGGGCUGUg----- 6 0,0 ---------------------------------------------CAACACCAGUCGAUGGGCUGUu----- 806 0,0 ---------------------------------------------CAACACCAGUCGAUGGGCUGUuu---- 176 0,0 ---------------------------------------------CAACACCAGUCGAUGGGCUGUC----- 12111 0,1 ---------------------------------------------CAACACCAGUCGAUGGGCUGUCa---- 1984 0,1 ---------------------------------------------CAACACCAGUCGAUGGGCUGUCaa--- 40 0,1 ---------------------------------------------CAACACCAGUCGAUGGGCUGUCau--- 207 0,1 ---------------------------------------------CAACACCAGUCGAUGGGCUGUCc---- 32 0,1 ---------------------------------------------CAACACCAGUCGAUGGGCUGUCg---- 83 0,1 ---------------------------------------------CAACACCAGUCGAUGGGCUGUCU---- 1636 0,2 ---------------------------------------------CAACACCAGUCGAUGGGCUGUCUa--- 2 0,2 ---------------------------------------------CAACACCAGUCGAUGGGCUGUCUu--- 61 0,2 ---------------------------------------------CAACACCAGUCGAUGGGCUGUCUuu-- 17 0,2 ----------------------------------------------AACACCAGUCGAUGGGCU-------- 2 1,-2 ----------------------------------------------AACACCAGUCGAUGGGCUG------- 5 1,-1 ----------------------------------------------AACACCAGUCGAUGGGCUGa------ 7 1,-1 ----------------------------------------------AACACCAGUCGAUGGGCUGc------ 2 1,-1 ----------------------------------------------AACACCAGUCGAUGGGCUGg------ 2 1,-1 ----------------------------------------------AACACCAGUCGAUGGGCUGU------ 544 1,0 ----------------------------------------------AACACCAGUCGAUGGGCUGUa----- 11 1,0 ----------------------------------------------AACACCAGUCGAUGGGCUGUaa---- 25 1,0 ----------------------------------------------AACACCAGUCGAUGGGCUGUu----- 18 1,0 ----------------------------------------------AACACCAGUCGAUGGGCUGUuu---- 4 1,0 ----------------------------------------------AACACCAGUCGAUGGGCUGUC----- 576 1,1 ----------------------------------------------AACACCAGUCGAUGGGCUGUCa---- 88 1,1 ----------------------------------------------AACACCAGUCGAUGGGCUGUCaa--- 7 1,1 ----------------------------------------------AACACCAGUCGAUGGGCUGUCau--- 8 1,1 ----------------------------------------------AACACCAGUCGAUGGGCUGUCU---- 407 1,2 ----------------------------------------------AACACCAGUCGAUGGGCUGUCUa--- 2 1,2 ----------------------------------------------AACACCAGUCGAUGGGCUGUCUu--- 19 1,2 ----------------------------------------------AACACCAGUCGAUGGGCUGUCUuu-- 12 1,2 -----------------------------------------------ACACCAGUCGAUGGGCUGU------ 4 2,0 -----------------------------------------------ACACCAGUCGAUGGGCUGUC----- 12 2,1 -----------------------------------------------ACACCAGUCGAUGGGCUGUCa---- 10 2,1 -----------------------------------------------ACACCAGUCGAUGGGCUGUCau--- 4 2,1 -----------------------------------------------ACACCAGUCGAUGGGCUGUCU---- 77 2,2 -----------------------------------------------ACACCAGUCGAUGGGCUGUCUu--- 2 2,2 -----------------------------------------------ACACCAGUCGAUGGGCUGUCUuu-- 2 2,2 >hsa-mir-210 3pM:66-87 Tumor acccggcagugccuccaggcgcagggcagccccugcccaccgcacacugcgcugccccagacccaCUGUGCGUGUGACAGCGGCUGAucugugccugggcagcgcgaccc ---------------------------AGCCCCUGCCCACCGCACACU-------------------------------------------------------------- 34 ---------------------------AGCCCCUGCCCACCGCACACUG------------------------------------------------------------- 37 ---------------------------AGCCCCUGCCCACCGCACACUGa------------------------------------------------------------ 7 ---------------------------AGCCCCUGCCCACCGCACACUGu------------------------------------------------------------ 4 ---------------------------AGCCCCUGCCCACCGCACACUGC------------------------------------------------------------ 3 ----------------------------GCCCCUGCCCACCGCACACU-------------------------------------------------------------- 2 ---------------------------------------------------------------CACUGUGCGUGUGACAGCGGCUGA----------------------- 2 -2,0 ----------------------------------------------------------------ACUGUGCGUGUGACAGCGGa-------------------------- 2 -1,-4 ----------------------------------------------------------------ACUGUGCGUGUGACAGCGGC-------------------------- 4 -1,-3 ----------------------------------------------------------------ACUGUGCGUGUGACAGCGGCU------------------------- 39 -1,-2 ----------------------------------------------------------------ACUGUGCGUGUGACAGCGGCUau----------------------- 2 -1,-2 ----------------------------------------------------------------ACUGUGCGUGUGACAGCGGCUG------------------------ 2 -1,-1 ----------------------------------------------------------------ACUGUGCGUGUGACAGCGGCUGg----------------------- 2 -1,-1 ----------------------------------------------------------------ACUGUGCGUGUGACAGCGGCUGu----------------------- 6 -1,-1 ----------------------------------------------------------------ACUGUGCGUGUGACAGCGGCUGA----------------------- 636 -1,0 ----------------------------------------------------------------ACUGUGCGUGUGACAGCGGCUGAa---------------------- 51 -1,0 ----------------------------------------------------------------ACUGUGCGUGUGACAGCGGCUGAau--------------------- 17 -1,0 ----------------------------------------------------------------ACUGUGCGUGUGACAGCGGCUGAU---------------------- 89 -1,1 ----------------------------------------------------------------ACUGUGCGUGUGACAGCGGCUGAUu--------------------- 11 -1,1 -----------------------------------------------------------------CUGUGCGUGUGACAGCGG--------------------------- 94 0,-4 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGa-------------------------- 21 0,-4 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGaa------------------------- 15 0,-4 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGC-------------------------- 40 0,-3 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCa------------------------- 4 0,-3 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCaa------------------------ 4 0,-3 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCau------------------------ 6 0,-3 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCU------------------------- 530 0,-2 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUa------------------------ 9 0,-2 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUaa----------------------- 65 0,-2 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUau----------------------- 15 0,-2 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUu------------------------ 56 0,-2 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUuu----------------------- 62 0,-2 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUG------------------------ 388 0,-1 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGc----------------------- 251 0,-1 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGg----------------------- 96 0,-1 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGu----------------------- 91 0,-1 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGuu---------------------- 9 0,-1 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGA----------------------- 18058 0,0 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAa---------------------- 2833 0,0 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAaa--------------------- 1222 0,0 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAau--------------------- 1256 0,0 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAc---------------------- 76 0,0 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAg---------------------- 86 0,0 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAU---------------------- 3818 0,1 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAUa--------------------- 176 0,1 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAUaa-------------------- 4 0,1 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAUau-------------------- 23 0,1 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAUg--------------------- 4 0,1 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAUu--------------------- 908 0,1 -----------------------------------------------------------------CUGUGCGUGUGACAGCGGCUGAUuu-------------------- 73 0,1 ------------------------------------------------------------------UGUGCGUGUGACAGCGGCU------------------------- 8 1,-2 ------------------------------------------------------------------UGUGCGUGUGACAGCGGCUaa----------------------- 2 1,-2 ------------------------------------------------------------------UGUGCGUGUGACAGCGGCUuu----------------------- 2 1,-2 ------------------------------------------------------------------UGUGCGUGUGACAGCGGCUG------------------------ 2 1,-1 ------------------------------------------------------------------UGUGCGUGUGACAGCGGCUGc----------------------- 2 1,-1 ------------------------------------------------------------------UGUGCGUGUGACAGCGGCUGA----------------------- 519 1,0 ------------------------------------------------------------------UGUGCGUGUGACAGCGGCUGAa---------------------- 61 1,0 ------------------------------------------------------------------UGUGCGUGUGACAGCGGCUGAaa--------------------- 13 1,0 ------------------------------------------------------------------UGUGCGUGUGACAGCGGCUGAau--------------------- 21 1,0 ------------------------------------------------------------------UGUGCGUGUGACAGCGGCUGAU---------------------- 126 1,1 ------------------------------------------------------------------UGUGCGUGUGACAGCGGCUGAUu--------------------- 35 1,1 -------------------------------------------------------------------GUGCGUGUGACAGCGGCUGA----------------------- 34 2,0 -------------------------------------------------------------------GUGCGUGUGACAGCGGCUGAa---------------------- 2 2,0 >hsa-mir-211 5pM:26-47 Tumor ucaccuggccaugugacuugugggcUUCCCUUUGUCAUCCUUCGCCUagggcucugagcagggcagggacagcaaaggggugcucaguugucacuucccacagcacggag -------------------------UUCCCUUUGUCAUCCUUCGCCU--------------------------------------------------------------- 3 0,0 >hsa-mir-2110 5pM:8-29 Tumor cagggguUUGGGGAAACGGCCGCUGAGUGaggcgucggcuguguuucucaccgcggucuuuuccucccacucuug -------UUGGGGAAACGGCCGCUGA------------------------------------------------- 2 0,-3 -------UUGGGGAAACGGCCGCUGAG------------------------------------------------ 5 0,-2 -------UUGGGGAAACGGCCGCUGAGa----------------------------------------------- 2 0,-2 -------UUGGGGAAACGGCCGCUGAGU----------------------------------------------- 71 0,-1 -------UUGGGGAAACGGCCGCUGAGUG---------------------------------------------- 16 0,0 -------UUGGGGAAACGGCCGCUGAGUGu--------------------------------------------- 13 0,0 -------UUGGGGAAACGGCCGCUGAGUGA--------------------------------------------- 123 0,1 -------UUGGGGAAACGGCCGCUGAGUGAa-------------------------------------------- 4 0,1 -------UUGGGGAAACGGCCGCUGAGUGAu-------------------------------------------- 4 0,1 -------UUGGGGAAACGGCCGCUGAGUGAG-------------------------------------------- 27 0,2 -------UUGGGGAAACGGCCGCUGAGUGAGa------------------------------------------- 2 0,2 -------UUGGGGAAACGGCCGCUGAGUGAGu------------------------------------------- 11 0,2 -----------------------------------------------UCACCGCGGUCUUUUCCUCCCA------ 2 -----------------------------------------------UCACCGCGGUCUUUUCCUCCCAC----- 2 ------------------------------------------------CACCGCGGUCUUUUCCUCCCA------ 2 ------------------------------------------------CACCGCGGUCUUUUCCUCCCAu----- 5 ------------------------------------------------CACCGCGGUCUUUUCCUCCCAuu---- 2 >hsa-mir-2114 MA:13-34;mi:49-69 Tumor ccuccaugcuccUAGUCCCUUCCUUGAAGCGGUCggauaaucacaugaCGAGCCUCAAGCAAGGGACUUcaagcuggugg ------------UAGUCCCUUCCUUGAAGCG------------------------------------------------- 3 0,-3 ------------UAGUCCCUUCCUUGAAGCGG------------------------------------------------ 26 0,-2 ------------UAGUCCCUUCCUUGAAGCGGU----------------------------------------------- 67 0,-1 ------------UAGUCCCUUCCUUGAAGCGGUa---------------------------------------------- 11 0,-1 ------------UAGUCCCUUCCUUGAAGCGGUau--------------------------------------------- 2 0,-1 ------------UAGUCCCUUCCUUGAAGCGGUu---------------------------------------------- 2 0,-1 ------------UAGUCCCUUCCUUGAAGCGGUC---------------------------------------------- 266 0,0 ------------UAGUCCCUUCCUUGAAGCGGUCu--------------------------------------------- 67 0,0 -------------AGUCCCUUCCUUGAAGCGGU----------------------------------------------- 2 1,-1 -------------AGUCCCUUCCUUGAAGCGGUC---------------------------------------------- 12 1,0 ------------------------------------------------CGAGCCUCAAGCAAGGGACU------------ 6 0,-1 ------------------------------------------------CGAGCCUCAAGCAAGGGACUU----------- 7 0,0 ------------------------------------------------CGAGCCUCAAGCAAGGGACUUC---------- 9 0,1 ------------------------------------------------CGAGCCUCAAGCAAGGGACUUCA--------- 18 0,2 -------------------------------------------------GAGCCUCAAGCAAGGGACUUCu--------- 2 1,1 >hsa-mir-2115 MA:21-42;mi:58-79 Tumor acugucaucccacugcuuccAGCUUCCAUGACUCCUGAUGGAggaaucacaugaauuCAUCAGAAUUCAUGGAGGCUAGaagcaguaugaggaucauuua -------------------CAGCUUCCAUGACUCCUGAUG------------------------------------------------------------ 2 -1,-2 -------------------CAGCUUCCAUGACUCCUGAUGG----------------------------------------------------------- 3 -1,-1 -------------------CAGCUUCCAUGACUCCUGAUGGA---------------------------------------------------------- 2 -1,0 --------------------AGCUUCCAUGACUCCUGA-------------------------------------------------------------- 2 0,-4 --------------------AGCUUCCAUGACUCCUGAU------------------------------------------------------------- 4 0,-3 --------------------AGCUUCCAUGACUCCUGAUG------------------------------------------------------------ 7 0,-2 --------------------AGCUUCCAUGACUCCUGAUGG----------------------------------------------------------- 57 0,-1 --------------------AGCUUCCAUGACUCCUGAUGGA---------------------------------------------------------- 236 0,0 --------------------AGCUUCCAUGACUCCUGAUGGAa--------------------------------------------------------- 14 0,0 --------------------AGCUUCCAUGACUCCUGAUGGAu--------------------------------------------------------- 2 0,0 ---------------------------------------------------------CAUCAGAAUUCAUGGAGGCUAG--------------------- 22 0,0 ---------------------------------------------------------CAUCAGAAUUCAUGGAGGCUAGu-------------------- 9 0,0 ---------------------------------------------------------CAUCAGAAUUCAUGGAGGCUAGA-------------------- 6 0,1 >hsa-mir-2116 MA:14-34;mi:51-71 Tumor gaccuaggcuaggGGUUCUUAGCAUAGGAGGUCUucccaugcuaagaaguCCUCCCAUGCCAAGAACUCCCagacuagga -------------GGUUCUUAGCAUAGGAGGUCUU--------------------------------------------- 2 0,1 >hsa-mir-212 3pM:71-91 Tumor cggggcaccccgcccggacagcgcgccggcaccuuggcucuagacugcuuacugcccgggccgcccucagUAACAGUCUCCAGUCACGGCCaccgacgccuggccccgcc ------------------------------ACCUUGGCUCUAGACUGCUU------------------------------------------------------------ 2 ------------------------------ACCUUGGCUCUAGACUGCUUA----------------------------------------------------------- 2 ------------------------------ACCUUGGCUCUAGACUGCUUAC---------------------------------------------------------- 4 ------------------------------ACCUUGGCUCUAGACUGCUUACU--------------------------------------------------------- 117 ----------------------------------------------------------------------UAACAGUCUCCAGUCACGG--------------------- 2 0,-2 ----------------------------------------------------------------------UAACAGUCUCCAGUCACGGC-------------------- 5 0,-1 ----------------------------------------------------------------------UAACAGUCUCCAGUCACGGCa------------------- 2 0,-1 ----------------------------------------------------------------------UAACAGUCUCCAGUCACGGCC------------------- 24 0,0 ----------------------------------------------------------------------UAACAGUCUCCAGUCACGGCCu------------------ 2 0,0 ----------------------------------------------------------------------UAACAGUCUCCAGUCACGGCCA------------------ 27 0,1 ----------------------------------------------------------------------UAACAGUCUCCAGUCACGGCCAu----------------- 12 0,1 >hsa-mir-214 mi:30-51;MA:71-92 Tumor ggccuggcuggacagaguugucaugugucUGCCUGUCUACACUUGCUGUGCagaacauccgcucaccuguACAGCAGGCACAGACAGGCAGUcacaugacaacccagccu ----------------------------CUGCCUGUCUACACUUGCUGUGa----------------------------------------------------------- 2 -1,-1 ----------------------------CUGCCUGUCUACACUUGCUGUGC----------------------------------------------------------- 2 -1,0 -----------------------------UGCCUGUCUACACUUGCUG-------------------------------------------------------------- 6 0,-3 -----------------------------UGCCUGUCUACACUUGCUGU------------------------------------------------------------- 104 0,-2 -----------------------------UGCCUGUCUACACUUGCUGUG------------------------------------------------------------ 332 0,-1 -----------------------------UGCCUGUCUACACUUGCUGUGa----------------------------------------------------------- 322 0,-1 -----------------------------UGCCUGUCUACACUUGCUGUGaa---------------------------------------------------------- 5 0,-1 -----------------------------UGCCUGUCUACACUUGCUGUGu----------------------------------------------------------- 94 0,-1 -----------------------------UGCCUGUCUACACUUGCUGUGC----------------------------------------------------------- 2355 0,0 -----------------------------UGCCUGUCUACACUUGCUGUGCu---------------------------------------------------------- 23 0,0 -----------------------------UGCCUGUCUACACUUGCUGUGCA---------------------------------------------------------- 15 0,1 ------------------------------GCCUGUCUACACUUGCUGU------------------------------------------------------------- 7 1,-2 ------------------------------GCCUGUCUACACUUGCUGUG------------------------------------------------------------ 26 1,-1 ------------------------------GCCUGUCUACACUUGCUGUGa----------------------------------------------------------- 13 1,-1 ------------------------------GCCUGUCUACACUUGCUGUGu----------------------------------------------------------- 12 1,-1 ------------------------------GCCUGUCUACACUUGCUGUGC----------------------------------------------------------- 505 1,0 ------------------------------GCCUGUCUACACUUGCUGUGCA---------------------------------------------------------- 110 1,1 ------------------------------GCCUGUCUACACUUGCUGUGCAGu-------------------------------------------------------- 2 1,2 -------------------------------CCUGUCUACACUUGCUGUGCAG--------------------------------------------------------- 2 2,2 --------------------------------------------------------------------GUACAGCAGGCACAGACAGG---------------------- 4 -2,-4 --------------------------------------------------------------------GUACAGCAGGCACAGACAGGC--------------------- 2 -2,-3 --------------------------------------------------------------------GUACAGCAGGCACAGACAGGCAa------------------- 2 -2,-2 --------------------------------------------------------------------GUACAGCAGGCACAGACAGGCAGU------------------ 2 -2,0 ---------------------------------------------------------------------UACAGCAGGCACAGACAG----------------------- 2 -1,-5 ---------------------------------------------------------------------UACAGCAGGCACAGACAGa---------------------- 7 -1,-5 ---------------------------------------------------------------------UACAGCAGGCACAGACAGG---------------------- 38 -1,-4 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGa--------------------- 14 -1,-4 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGu--------------------- 3 -1,-4 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGC--------------------- 27 -1,-3 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCA-------------------- 22 -1,-2 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAa------------------- 58 -1,-2 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAaa------------------ 12 -1,-2 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAau------------------ 14 -1,-2 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAu------------------- 28 -1,-2 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAuu------------------ 8 -1,-2 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAG------------------- 168 -1,-1 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAGa------------------ 145 -1,-1 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAGaa----------------- 10 -1,-1 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAGg------------------ 21 -1,-1 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAGU------------------ 159 -1,0 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAGUa----------------- 10 -1,0 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAGUau---------------- 2 -1,0 ---------------------------------------------------------------------UACAGCAGGCACAGACAGGCAGUu----------------- 9 -1,0 ----------------------------------------------------------------------ACAGCAGGCACAGACAGG---------------------- 25 0,-4 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGa--------------------- 8 0,-4 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGaa-------------------- 4 0,-4 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGC--------------------- 11 0,-3 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCA-------------------- 40 0,-2 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAa------------------- 90 0,-2 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAaa------------------ 49 0,-2 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAau------------------ 16 0,-2 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAu------------------- 11 0,-2 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAuu------------------ 4 0,-2 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAG------------------- 399 0,-1 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGa------------------ 297 0,-1 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGaa----------------- 96 0,-1 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGau----------------- 4 0,-1 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGc------------------ 2 0,-1 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGg------------------ 89 0,-1 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGU------------------ 690 0,0 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGUa----------------- 173 0,0 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGUaa---------------- 48 0,0 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGUau---------------- 74 0,0 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGUg----------------- 2 0,0 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGUu----------------- 112 0,0 ----------------------------------------------------------------------ACAGCAGGCACAGACAGGCAGUuu---------------- 17 0,0 -----------------------------------------------------------------------CAGCAGGCACAGACAGGCAG------------------- 2 1,-1 -----------------------------------------------------------------------CAGCAGGCACAGACAGGCAGU------------------ 9 1,0 -----------------------------------------------------------------------CAGCAGGCACAGACAGGCAGUu----------------- 2 1,0 >hsa-mir-215 5pM:27-47 Tumor aucauucagaaaugguauacaggaaaAUGACCUAUGAAUUGACAGACaauauagcugaguuugucugucauuucuuuaggccaauauucuguaugacugugcuacuucaa --------------------------AUGACCUAUGAAUUGACAGA---------------------------------------------------------------- 4 0,-1 --------------------------AUGACCUAUGAAUUGACAGAC--------------------------------------------------------------- 24 0,0 --------------------------AUGACCUAUGAAUUGACAGACA-------------------------------------------------------------- 34 0,1 ---------------------------UGACCUAUGAAUUGACAG----------------------------------------------------------------- 5 1,-2 ---------------------------UGACCUAUGAAUUGACAGA---------------------------------------------------------------- 3 1,-1 >hsa-mir-216a 5pM:19-40 Tumor gauggcugugaguuggcuUAAUCUCAGCUGGCAACUGUGAgauguucauacaaucccucacaguggucucugggauuaugcuaaacagagcaauuuccuagcccucacga ------------------UAAUCUCAGCUGGCAACUGUGA---------------------------------------------------------------------- 24 0,0 ------------------UAAUCUCAGCUGGCAACUGUGAGu-------------------------------------------------------------------- 2 0,1 >hsa-mir-217 5pM:35-57 Tumor aguauaauuauuacauaguuuuugaugucgcagaUACUGCAUCAGGAACUGAUUGGAuaagaaucagucaccaucaguuccuaaugcauugccuucagcaucuaaacaag ----------------------------------UACUGCAUCAGGAACUGAUUGG------------------------------------------------------ 13 0,-1 ----------------------------------UACUGCAUCAGGAACUGAUUGGA----------------------------------------------------- 20 0,0 >hsa-mir-218-1 MA:25-45;mi:68-89 Tumor gugauaauguagcgagauuuucugUUGUGCUUGAUCUAACCAUGUgguugcgagguaugaguaaaacAUGGUUCCGUCAAGCACCAUGGaacgucacgcagcuuucuaca ------------------------UUGUGCUUGAUCUAACCA-------------------------------------------------------------------- 2 0,-3 ------------------------UUGUGCUUGAUCUAACCAU------------------------------------------------------------------- 2 0,-2 ------------------------UUGUGCUUGAUCUAACCAUau----------------------------------------------------------------- 2 0,-2 ------------------------UUGUGCUUGAUCUAACCAUuu----------------------------------------------------------------- 2 0,-2 ------------------------UUGUGCUUGAUCUAACCAUG------------------------------------------------------------------ 148 0,-1 ------------------------UUGUGCUUGAUCUAACCAUGa----------------------------------------------------------------- 6 0,-1 ------------------------UUGUGCUUGAUCUAACCAUGU----------------------------------------------------------------- 2852 0,0 ------------------------UUGUGCUUGAUCUAACCAUGUa---------------------------------------------------------------- 32 0,0 ------------------------UUGUGCUUGAUCUAACCAUGUaa--------------------------------------------------------------- 7 0,0 ------------------------UUGUGCUUGAUCUAACCAUGUu---------------------------------------------------------------- 16 0,0 ------------------------UUGUGCUUGAUCUAACCAUGUG---------------------------------------------------------------- 1130 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGa--------------------------------------------------------------- 859 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGaa-------------------------------------------------------------- 5 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGau-------------------------------------------------------------- 2 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGu--------------------------------------------------------------- 422 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGuu-------------------------------------------------------------- 2 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGG--------------------------------------------------------------- 115 0,2 ------------------------UUGUGCUUGAUCUAACCAUGUGGa-------------------------------------------------------------- 2 0,2 ------------------------UUGUGCUUGAUCUAACCAUGUGGU-------------------------------------------------------------- 186 0,3 ------------------------UUGUGCUUGAUCUAACCAUGUGGUU------------------------------------------------------------- 25 0,4 -------------------------UGUGCUUGAUCUAACCAUGU----------------------------------------------------------------- 44 1,0 -------------------------UGUGCUUGAUCUAACCAUGUG---------------------------------------------------------------- 11 1,1 -------------------------UGUGCUUGAUCUAACCAUGUGa--------------------------------------------------------------- 7 1,1 --------------------------GUGCUUGAUCUAACCAUGU----------------------------------------------------------------- 2 2,0 --------------------------GUGCUUGAUCUAACCAUGUG---------------------------------------------------------------- 2 2,1 ------------------------------------------------------------------CAUGGUUCCGUCAAGCACCAU----------------------- 2 -1,-2 ------------------------------------------------------------------CAUGGUUCCGUCAAGCACCAUu---------------------- 2 -1,-2 >hsa-mir-218-2 MA:25-45;mi:67-88 Tumor gaccagucgcugcggggcuuuccuUUGUGCUUGAUCUAACCAUGUgguggaacgauggaaacggaaCAUGGUUCUGUCAAGCACCGCGgaaagcaccgugcucuccugca ------------------------UUGUGCUUGAUCUAACCA-------------------------------------------------------------------- 2 0,-3 ------------------------UUGUGCUUGAUCUAACCAU------------------------------------------------------------------- 2 0,-2 ------------------------UUGUGCUUGAUCUAACCAUau----------------------------------------------------------------- 2 0,-2 ------------------------UUGUGCUUGAUCUAACCAUuu----------------------------------------------------------------- 2 0,-2 ------------------------UUGUGCUUGAUCUAACCAUG------------------------------------------------------------------ 148 0,-1 ------------------------UUGUGCUUGAUCUAACCAUGa----------------------------------------------------------------- 6 0,-1 ------------------------UUGUGCUUGAUCUAACCAUGU----------------------------------------------------------------- 2852 0,0 ------------------------UUGUGCUUGAUCUAACCAUGUa---------------------------------------------------------------- 32 0,0 ------------------------UUGUGCUUGAUCUAACCAUGUaa--------------------------------------------------------------- 7 0,0 ------------------------UUGUGCUUGAUCUAACCAUGUu---------------------------------------------------------------- 16 0,0 ------------------------UUGUGCUUGAUCUAACCAUGUG---------------------------------------------------------------- 1130 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGa--------------------------------------------------------------- 859 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGaa-------------------------------------------------------------- 5 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGau-------------------------------------------------------------- 2 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGu--------------------------------------------------------------- 422 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGuu-------------------------------------------------------------- 2 0,1 ------------------------UUGUGCUUGAUCUAACCAUGUGG--------------------------------------------------------------- 115 0,2 ------------------------UUGUGCUUGAUCUAACCAUGUGGa-------------------------------------------------------------- 2 0,2 ------------------------UUGUGCUUGAUCUAACCAUGUGGU-------------------------------------------------------------- 186 0,3 -------------------------UGUGCUUGAUCUAACCAUGU----------------------------------------------------------------- 44 1,0 -------------------------UGUGCUUGAUCUAACCAUGUG---------------------------------------------------------------- 11 1,1 -------------------------UGUGCUUGAUCUAACCAUGUGa--------------------------------------------------------------- 7 1,1 --------------------------GUGCUUGAUCUAACCAUGU----------------------------------------------------------------- 2 2,0 --------------------------GUGCUUGAUCUAACCAUGUG---------------------------------------------------------------- 2 2,1 >hsa-mir-219-1 5p:21-41;3p:62-83 Tumor ccgccccgggccgcggcuccUGAUUGUCCAAACGCAAUUCUcgagucuauggcuccggccgAGAGUUGAGUCUGGACGUCCCGagccgccgcccccaaaccucgagcggg --------------------UGAUUGUCCAAACGCAAUU----------------------------------------------------------------------- 19 0,-2 --------------------UGAUUGUCCAAACGCAAUUC---------------------------------------------------------------------- 24 0,-1 --------------------UGAUUGUCCAAACGCAAUUCU--------------------------------------------------------------------- 50 0,0 --------------------UGAUUGUCCAAACGCAAUUCUC-------------------------------------------------------------------- 20 0,1 --------------------UGAUUGUCCAAACGCAAUUCUCG------------------------------------------------------------------- 186 0,2 --------------------UGAUUGUCCAAACGCAAUUCUCGu------------------------------------------------------------------ 2 0,2 --------------------UGAUUGUCCAAACGCAAUUCUCGA------------------------------------------------------------------ 2 0,3 ---------------------GAUUGUCCAAACGCAAUUCUCG------------------------------------------------------------------- 2 1,2 -------------------------------------------------------------AGAGUUGAGUCUGGACGUCCCG--------------------------- 4 0,0 >hsa-mir-219-2 5p:19-39;3p:62-83 Tumor acucaggggcuucgccacUGAUUGUCCAAACGCAAUUCUuguacgagucugcggccaaccgAGAAUUGUGGCUGGACAUCUGUggcugagcuccggg ------------------UGAUUGUCCAAACGCAAUU------------------------------------------------------------ 19 0,-2 ------------------UGAUUGUCCAAACGCAAUUC----------------------------------------------------------- 24 0,-1 ------------------UGAUUGUCCAAACGCAAUUCU---------------------------------------------------------- 50 0,0 >hsa-mir-22 mi:15-36;MA:53-74 Tumor ggcugagccgcaguAGUUCUUCAGUGGCAAGCUUUAuguccugacccagcuaAAGCUGCCAGUUGAAGAACUGUugcccucugcc --------------AGUUCUUCAGUGGCAAGC----------------------------------------------------- 8 0,-4 --------------AGUUCUUCAGUGGCAAGCU---------------------------------------------------- 163 0,-3 --------------AGUUCUUCAGUGGCAAGCUU--------------------------------------------------- 322 0,-2 --------------AGUUCUUCAGUGGCAAGCUUa-------------------------------------------------- 4 0,-2 --------------AGUUCUUCAGUGGCAAGCUUU-------------------------------------------------- 3091 0,-1 --------------AGUUCUUCAGUGGCAAGCUUUc------------------------------------------------- 2 0,-1 --------------AGUUCUUCAGUGGCAAGCUUUu------------------------------------------------- 155 0,-1 --------------AGUUCUUCAGUGGCAAGCUUUA------------------------------------------------- 2154 0,0 --------------AGUUCUUCAGUGGCAAGCUUUAa------------------------------------------------ 220 0,0 --------------AGUUCUUCAGUGGCAAGCUUUAg------------------------------------------------ 2 0,0 --------------AGUUCUUCAGUGGCAAGCUUUAU------------------------------------------------ 75 0,1 ---------------GUUCUUCAGUGGCAAGCUUU-------------------------------------------------- 40 1,-1 ---------------GUUCUUCAGUGGCAAGCUUUA------------------------------------------------- 28 1,0 ---------------------------------------------------AAAGCUGCCAGUUGAAGAACU------------- 4 -1,-2 ---------------------------------------------------AAAGCUGCCAGUUGAAGAACUG------------ 6 -1,-1 ---------------------------------------------------AAAGCUGCCAGUUGAAGAACUGU----------- 124 -1,0 ----------------------------------------------------AAGCUGCCAGUUGAAGAA--------------- 7026 0,-4 ----------------------------------------------------AAGCUGCCAGUUGAAGAAa-------------- 1116 0,-4 ----------------------------------------------------AAGCUGCCAGUUGAAGAAaa------------- 87 0,-4 ----------------------------------------------------AAGCUGCCAGUUGAAGAAau------------- 93 0,-4 ----------------------------------------------------AAGCUGCCAGUUGAAGAAg-------------- 8 0,-4 ----------------------------------------------------AAGCUGCCAGUUGAAGAAu-------------- 91 0,-4 ----------------------------------------------------AAGCUGCCAGUUGAAGAAuu------------- 29 0,-4 ----------------------------------------------------AAGCUGCCAGUUGAAGAAC-------------- 5248 0,-3 ----------------------------------------------------AAGCUGCCAGUUGAAGAACa------------- 118 0,-3 ----------------------------------------------------AAGCUGCCAGUUGAAGAACaa------------ 8 0,-3 ----------------------------------------------------AAGCUGCCAGUUGAAGAACc------------- 26 0,-3 ----------------------------------------------------AAGCUGCCAGUUGAAGAACU------------- 23854 0,-2 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUa------------ 326 0,-2 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUaa----------- 52 0,-2 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUau----------- 1597 0,-2 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUc------------ 3 0,-2 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUu------------ 451 0,-2 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUuu----------- 1577 0,-2 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUG------------ 38532 0,-1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGa----------- 8984 0,-1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGaa---------- 320 0,-1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGau---------- 51 0,-1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGc----------- 5467 0,-1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGg----------- 1356 0,-1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGU----------- 780763 0,0 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUa---------- 15138 0,0 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUaa--------- 1635 0,0 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUau--------- 770 0,0 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUc---------- 122 0,0 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUg---------- 105 0,0 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUU---------- 20492 0,1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUUa--------- 293 0,1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUUu--------- 1207 0,1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUUuu-------- 4 0,1 ----------------------------------------------------AAGCUGCCAGUUGAAGAACUGUUG--------- 14 0,2 -----------------------------------------------------AGCUGCCAGUUGAAGAAC-------------- 78 1,-3 -----------------------------------------------------AGCUGCCAGUUGAAGAACU------------- 572 1,-2 -----------------------------------------------------AGCUGCCAGUUGAAGAACUa------------ 4 1,-2 -----------------------------------------------------AGCUGCCAGUUGAAGAACUau----------- 26 1,-2 -----------------------------------------------------AGCUGCCAGUUGAAGAACUu------------ 7 1,-2 -----------------------------------------------------AGCUGCCAGUUGAAGAACUuu----------- 9 1,-2 -----------------------------------------------------AGCUGCCAGUUGAAGAACUG------------ 1064 1,-1 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGa----------- 189 1,-1 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGaa---------- 6 1,-1 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGc----------- 119 1,-1 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGg----------- 12 1,-1 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGU----------- 21479 1,0 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGUa---------- 426 1,0 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGUaa--------- 60 1,0 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGUau--------- 29 1,0 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGUU---------- 681 1,1 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGUUa--------- 2 1,1 -----------------------------------------------------AGCUGCCAGUUGAAGAACUGUUu--------- 66 1,1 ------------------------------------------------------GCUGCCAGUUGAAGAACU------------- 2 2,-2 ------------------------------------------------------GCUGCCAGUUGAAGAACUGU----------- 201 2,0 ------------------------------------------------------GCUGCCAGUUGAAGAACUGUa---------- 4 2,0 ------------------------------------------------------GCUGCCAGUUGAAGAACUGUU---------- 5 2,1 ------------------------------------------------------GCUGCCAGUUGAAGAACUGUUu--------- 23 2,1 >hsa-mir-221 mi:25-46;MA:65-87 Tumor ugaacauccaggucuggggcaugaACCUGGCAUACAAUGUAGAUUUcuguguucguuaggcaacAGCUACAUUGUCUGCUGGGUUUCaggcuaccuggaaacauguucuc -----------------------AACCUGGCAUACAAUGUAGAUU----------------------------------------------------------------- 2 -1,-1 -----------------------AACCUGGCAUACAAUGUAGAUUUC--------------------------------------------------------------- 2 -1,1 ------------------------ACCUGGCAUACAAUGUAGA------------------------------------------------------------------- 19 0,-3 ------------------------ACCUGGCAUACAAUGUAGAa------------------------------------------------------------------ 2 0,-3 ------------------------ACCUGGCAUACAAUGUAGAU------------------------------------------------------------------ 51 0,-2 ------------------------ACCUGGCAUACAAUGUAGAUa----------------------------------------------------------------- 2 0,-2 ------------------------ACCUGGCAUACAAUGUAGAUU----------------------------------------------------------------- 184 0,-1 ------------------------ACCUGGCAUACAAUGUAGAUUU---------------------------------------------------------------- 186 0,0 ------------------------ACCUGGCAUACAAUGUAGAUUUC--------------------------------------------------------------- 130 0,1 ------------------------ACCUGGCAUACAAUGUAGAUUUCU-------------------------------------------------------------- 66 0,2 ------------------------ACCUGGCAUACAAUGUAGAUUUCUG------------------------------------------------------------- 17 0,3 ---------------------------------------------------------------CAGCUACAUUGUCUGCUGGG--------------------------- 2 -1,-4 ---------------------------------------------------------------CAGCUACAUUGUCUGCUGGGU-------------------------- 48 -1,-3 ---------------------------------------------------------------CAGCUACAUUGUCUGCUGGGUU------------------------- 124 -1,-2 ---------------------------------------------------------------CAGCUACAUUGUCUGCUGGGUUU------------------------ 75 -1,-1 ---------------------------------------------------------------CAGCUACAUUGUCUGCUGGGUUUC----------------------- 2 -1,0 ----------------------------------------------------------------AGCUACAUUGUCUGCUGG---------------------------- 174 0,-5 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGa--------------------------- 14 0,-5 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGaa-------------------------- 6 0,-5 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGau-------------------------- 5 0,-5 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGu--------------------------- 2 0,-5 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGuu-------------------------- 19 0,-5 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGG--------------------------- 1576 0,-4 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGa-------------------------- 305 0,-4 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGaa------------------------- 49 0,-4 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGau------------------------- 20 0,-4 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGc-------------------------- 2 0,-4 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGg-------------------------- 51 0,-4 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGU-------------------------- 7126 0,-3 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUa------------------------- 223 0,-3 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUaa------------------------ 244 0,-3 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUau------------------------ 206 0,-3 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUc------------------------- 4 0,-3 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUg------------------------- 2 0,-3 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUU------------------------- 13601 0,-2 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUa------------------------ 1271 0,-2 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUaa----------------------- 584 0,-2 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUau----------------------- 779 0,-2 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUc------------------------ 101 0,-2 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUg------------------------ 53 0,-2 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUU------------------------ 36478 0,-1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUa----------------------- 1486 0,-1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUaa---------------------- 173 0,-1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUau---------------------- 204 0,-1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUg----------------------- 61 0,-1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUu----------------------- 6680 0,-1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUuu---------------------- 487 0,-1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUC----------------------- 12644 0,0 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUCc---------------------- 2 0,0 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUCg---------------------- 27 0,0 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUCu---------------------- 1328 0,0 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUCuu--------------------- 5 0,0 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUCA---------------------- 571 0,1 ----------------------------------------------------------------AGCUACAUUGUCUGCUGGGUUUCAu--------------------- 4 0,1 -----------------------------------------------------------------GCUACAUUGUCUGCUGGG--------------------------- 37 1,-4 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGU-------------------------- 206 1,-3 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUa------------------------- 4 1,-3 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUaa------------------------ 4 1,-3 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUau------------------------ 4 1,-3 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUU------------------------- 583 1,-2 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUa------------------------ 26 1,-2 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUaa----------------------- 10 1,-2 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUau----------------------- 17 1,-2 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUU------------------------ 1514 1,-1 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUUa----------------------- 43 1,-1 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUUu----------------------- 229 1,-1 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUUuu---------------------- 11 1,-1 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUUC----------------------- 468 1,0 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUUCu---------------------- 43 1,0 -----------------------------------------------------------------GCUACAUUGUCUGCUGGGUUUCA---------------------- 7 1,1 ------------------------------------------------------------------CUACAUUGUCUGCUGGGUUUC----------------------- 6 2,0 >hsa-mir-222 mi:31-52;MA:69-89 Tumor gcugcuggaagguguagguacccucaauggCUCAGUAGCCAGUGUAGAUCCUgucuuucguaaucagcAGCUACAUCUGGCUACUGGGUcucugauggcaucuucuagcu ----------------------------GGCUCAGUAGCCAGUGUAGA-------------------------------------------------------------- 8 -2,-4 ----------------------------GGCUCAGUAGCCAGUGUAGAU------------------------------------------------------------- 17 -2,-3 ----------------------------GGCUCAGUAGCCAGUGUAGAUu------------------------------------------------------------ 2 -2,-3 ----------------------------GGCUCAGUAGCCAGUGUAGAUC------------------------------------------------------------ 84 -2,-2 ----------------------------GGCUCAGUAGCCAGUGUAGAUCC----------------------------------------------------------- 35 -2,-1 -------------------------------------------------------------------CAGCUACAUCUGGCUACUGGGU--------------------- 12 -1,0 -------------------------------------------------------------------CAGCUACAUCUGGCUACUGGGUu-------------------- 2 -1,0 -------------------------------------------------------------------CAGCUACAUCUGGCUACUGGGUuu------------------- 2 -1,0 -------------------------------------------------------------------CAGCUACAUCUGGCUACUGGGUC-------------------- 4 -1,1 -------------------------------------------------------------------CAGCUACAUCUGGCUACUGGGUCU------------------- 10 -1,2 --------------------------------------------------------------------AGCUACAUCUGGCUACUG------------------------ 93 0,-3 --------------------------------------------------------------------AGCUACAUCUGGCUACUGa----------------------- 27 0,-3 --------------------------------------------------------------------AGCUACAUCUGGCUACUGaa---------------------- 4 0,-3 --------------------------------------------------------------------AGCUACAUCUGGCUACUGu----------------------- 10 0,-3 --------------------------------------------------------------------AGCUACAUCUGGCUACUGG----------------------- 517 0,-2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGa---------------------- 142 0,-2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGaa--------------------- 90 0,-2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGau--------------------- 40 0,-2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGu---------------------- 12 0,-2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGuu--------------------- 19 0,-2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGG---------------------- 1097 0,-1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGa--------------------- 1150 0,-1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGaa-------------------- 251 0,-1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGau-------------------- 36 0,-1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGc--------------------- 40 0,-1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGg--------------------- 110 0,-1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGU--------------------- 16058 0,0 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUa-------------------- 621 0,0 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUaa------------------- 511 0,0 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUau------------------- 424 0,0 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUg-------------------- 9 0,0 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUu-------------------- 593 0,0 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUuu------------------- 105 0,0 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUC-------------------- 6920 0,1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCa------------------- 1059 0,1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCaa------------------ 21 0,1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCau------------------ 94 0,1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCc------------------- 18 0,1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCg------------------- 100 0,1 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCU------------------- 11236 0,2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUa------------------ 74 0,2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUaa----------------- 6 0,2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUau----------------- 41 0,2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUg------------------ 5 0,2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUu------------------ 1128 0,2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUuu----------------- 403 0,2 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUC------------------ 5561 0,3 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUCa----------------- 410 0,3 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUCc----------------- 169 0,3 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUCg----------------- 10 0,3 --------------------------------------------------------------------AGCUACAUCUGGCUACUGGGUCUCU----------------- 2818 0,4 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGG---------------------- 16 1,-1 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGa--------------------- 33 1,-1 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGaa-------------------- 2 1,-1 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGg--------------------- 2 1,-1 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGU--------------------- 500 1,0 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUa-------------------- 6 1,0 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUaa------------------- 15 1,0 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUau------------------- 2 1,0 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUu-------------------- 4 1,0 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUuu------------------- 2 1,0 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUC-------------------- 209 1,1 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUCa------------------- 11 1,1 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUCU------------------- 372 1,2 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUCUu------------------ 28 1,2 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUCUuu----------------- 2 1,2 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUCUC------------------ 160 1,3 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUCUCa----------------- 6 1,3 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUCUCau---------------- 2 1,3 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUCUCc----------------- 2 1,3 ---------------------------------------------------------------------GCUACAUCUGGCUACUGGGUCUCU----------------- 66 1,4 ----------------------------------------------------------------------CUACAUCUGGCUACUGGGU--------------------- 7 2,0 ----------------------------------------------------------------------CUACAUCUGGCUACUGGGUC-------------------- 2 2,1 ----------------------------------------------------------------------CUACAUCUGGCUACUGGGUCU------------------- 11 2,2 >hsa-mir-223 mi:26-47;MA:68-89 Tumor ccuggccuccugcagugccacgcucCGUGUAUUUGACAAGCUGAGUUggacacuccaugugguagagUGUCAGUUUGUCAAAUACCCCAagugcggcacaugcuuaccag -------------------------CGUGUAUUUGACAAGCUGAGU---------------------------------------------------------------- 11 0,-1 -------------------------CGUGUAUUUGACAAGCUGAGUU--------------------------------------------------------------- 24 0,0 -------------------------CGUGUAUUUGACAAGCUGAGUUG-------------------------------------------------------------- 47 0,1 -------------------------CGUGUAUUUGACAAGCUGAGUUGu------------------------------------------------------------- 5 0,1 -------------------------CGUGUAUUUGACAAGCUGAGUUGG------------------------------------------------------------- 10 0,2 -------------------------CGUGUAUUUGACAAGCUGAGUUGGA------------------------------------------------------------ 2 0,3 ------------------------------------------------------------------GUGUCAGUUUGUCAAAUACC------------------------ 4 -1,-3 ------------------------------------------------------------------GUGUCAGUUUGUCAAAUACCC----------------------- 2 -1,-2 ------------------------------------------------------------------GUGUCAGUUUGUCAAAUACCCu---------------------- 2 -1,-2 ------------------------------------------------------------------GUGUCAGUUUGUCAAAUACCCC---------------------- 4 -1,-1 ------------------------------------------------------------------GUGUCAGUUUGUCAAAUACCCCA--------------------- 36 -1,0 -------------------------------------------------------------------UGUCAGUUUGUCAAAUAC------------------------- 91 0,-4 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACa------------------------ 9 0,-4 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACu------------------------ 3 0,-4 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACC------------------------ 1149 0,-3 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCa----------------------- 40 0,-3 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCuu---------------------- 2 0,-3 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCC----------------------- 719 0,-2 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCa---------------------- 19 0,-2 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCaa--------------------- 15 0,-2 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCu---------------------- 8 0,-2 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCuu--------------------- 12 0,-2 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCC---------------------- 1171 0,-1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCc--------------------- 156 0,-1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCg--------------------- 2 0,-1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCu--------------------- 80 0,-1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCuu-------------------- 2 0,-1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCA--------------------- 7557 0,0 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAc-------------------- 33 0,0 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAg-------------------- 77 0,0 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAu-------------------- 2152 0,0 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAuu------------------- 338 0,0 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAA-------------------- 3120 0,1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAAa------------------- 283 0,1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAAaa------------------ 9 0,1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAAau------------------ 2 0,1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAAc------------------- 7 0,1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAAu------------------- 938 0,1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAAuu------------------ 10 0,1 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAAG------------------- 84 0,2 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAAGa------------------ 5 0,2 -------------------------------------------------------------------UGUCAGUUUGUCAAAUACCCCAAGU------------------ 2 0,3 --------------------------------------------------------------------GUCAGUUUGUCAAAUACC------------------------ 7 1,-3 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCC----------------------- 16 1,-2 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCCC---------------------- 40 1,-1 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCCCA--------------------- 618 1,0 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCCCAc-------------------- 3 1,0 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCCCAu-------------------- 84 1,0 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCCCAuu------------------- 6 1,0 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCCCAA-------------------- 471 1,1 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCCCAAa------------------- 20 1,1 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCCCAAu------------------- 78 1,1 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCCCAAG------------------- 3 1,2 --------------------------------------------------------------------GUCAGUUUGUCAAAUACCCCAAGU------------------ 2 1,3 >hsa-mir-224 MA:8-28;mi:53-75 Tumor gggcuuuCAAGUCACUAGUGGUUCCGUUuaguagaugauugugcauuguuucAAAAUGGUGCCCUAGUGACUACAaagccc ------UCAAGUCACUAGUGGUUCCGUU----------------------------------------------------- 2 -1,0 ------UCAAGUCACUAGUGGUUCCGUUU---------------------------------------------------- 10 -1,1 ------UCAAGUCACUAGUGGUUCCGUUUAG-------------------------------------------------- 4 -1,3 -------CAAGUCACUAGUGGUUCC-------------------------------------------------------- 60 0,-3 -------CAAGUCACUAGUGGUUCCG------------------------------------------------------- 63 0,-2 -------CAAGUCACUAGUGGUUCCGa------------------------------------------------------ 2 0,-2 -------CAAGUCACUAGUGGUUCCGU------------------------------------------------------ 132 0,-1 -------CAAGUCACUAGUGGUUCCGUa----------------------------------------------------- 4 0,-1 -------CAAGUCACUAGUGGUUCCGUaa---------------------------------------------------- 5 0,-1 -------CAAGUCACUAGUGGUUCCGUau---------------------------------------------------- 2 0,-1 -------CAAGUCACUAGUGGUUCCGUU----------------------------------------------------- 1759 0,0 -------CAAGUCACUAGUGGUUCCGUUa---------------------------------------------------- 145 0,0 -------CAAGUCACUAGUGGUUCCGUUaa--------------------------------------------------- 16 0,0 -------CAAGUCACUAGUGGUUCCGUUau--------------------------------------------------- 11 0,0 -------CAAGUCACUAGUGGUUCCGUUc---------------------------------------------------- 18 0,0 -------CAAGUCACUAGUGGUUCCGUUU---------------------------------------------------- 14233 0,1 -------CAAGUCACUAGUGGUUCCGUUUc--------------------------------------------------- 8 0,1 -------CAAGUCACUAGUGGUUCCGUUUg--------------------------------------------------- 8 0,1 -------CAAGUCACUAGUGGUUCCGUUUu--------------------------------------------------- 585 0,1 -------CAAGUCACUAGUGGUUCCGUUUuu-------------------------------------------------- 25 0,1 -------CAAGUCACUAGUGGUUCCGUUUA--------------------------------------------------- 1540 0,2 -------CAAGUCACUAGUGGUUCCGUUUAa-------------------------------------------------- 106 0,2 -------CAAGUCACUAGUGGUUCCGUUUAaa------------------------------------------------- 2 0,2 -------CAAGUCACUAGUGGUUCCGUUUAc-------------------------------------------------- 3 0,2 -------CAAGUCACUAGUGGUUCCGUUUAu-------------------------------------------------- 122 0,2 -------CAAGUCACUAGUGGUUCCGUUUAuu------------------------------------------------- 13 0,2 -------CAAGUCACUAGUGGUUCCGUUUAG-------------------------------------------------- 4604 0,3 -------CAAGUCACUAGUGGUUCCGUUUAGa------------------------------------------------- 44 0,3 -------CAAGUCACUAGUGGUUCCGUUUAGU------------------------------------------------- 491 0,4 --------AAGUCACUAGUGGUUCCGUU----------------------------------------------------- 40 1,0 --------AAGUCACUAGUGGUUCCGUUU---------------------------------------------------- 240 1,1 --------AAGUCACUAGUGGUUCCGUUUu--------------------------------------------------- 2 1,1 --------AAGUCACUAGUGGUUCCGUUUA--------------------------------------------------- 17 1,2 --------AAGUCACUAGUGGUUCCGUUUAu-------------------------------------------------- 2 1,2 --------AAGUCACUAGUGGUUCCGUUUAG-------------------------------------------------- 87 1,3 --------AAGUCACUAGUGGUUCCGUUUAGU------------------------------------------------- 6 1,4 ---------------------------------------------------CAAAAUGGUGCCCUAGUGAC---------- 2 -1,-4 ---------------------------------------------------CAAAAUGGUGCCCUAGUGACU--------- 7 -1,-3 ----------------------------------------------------AAAAUGGUGCCCUAGUGACU--------- 4 0,-3 ----------------------------------------------------AAAAUGGUGCCCUAGUGACUAu------- 2 0,-2 ----------------------------------------------------AAAAUGGUGCCCUAGUGACUAC------- 7 0,-1 ----------------------------------------------------AAAAUGGUGCCCUAGUGACUACA------ 4 0,0 -----------------------------------------------------AAAUGGUGCCCUAGUGACa--------- 2 1,-4 -----------------------------------------------------AAAUGGUGCCCUAGUGACU--------- 69 1,-3 -----------------------------------------------------AAAUGGUGCCCUAGUGACUA-------- 8 1,-2 -----------------------------------------------------AAAUGGUGCCCUAGUGACUAa------- 6 1,-2 -----------------------------------------------------AAAUGGUGCCCUAGUGACUAu------- 7 1,-2 -----------------------------------------------------AAAUGGUGCCCUAGUGACUAuu------ 17 1,-2 -----------------------------------------------------AAAUGGUGCCCUAGUGACUAC------- 93 1,-1 -----------------------------------------------------AAAUGGUGCCCUAGUGACUACu------ 36 1,-1 -----------------------------------------------------AAAUGGUGCCCUAGUGACUACA------ 417 1,0 -----------------------------------------------------AAAUGGUGCCCUAGUGACUACAA----- 12 1,1 ------------------------------------------------------AAUGGUGCCCUAGUGACUA-------- 2 2,-2 ------------------------------------------------------AAUGGUGCCCUAGUGACUAC------- 4 2,-1 ------------------------------------------------------AAUGGUGCCCUAGUGACUACA------ 72 2,0 ------------------------------------------------------AAUGGUGCCCUAGUGACUACAA----- 13 2,1 >hsa-mir-2276 3pM:54-75 Tumor guguucuuccaguccgcccucugucaccuugcagacggcuuucucuccgaaugUCUGCAAGUGUCAGAGGCGAGGaguggcagcugcau ---------------GCCCUCUGUCACCUUGCAGACG---------------------------------------------------- 6 >hsa-mir-2277 5p:18-41;3p:59-79 Tumor gugcuuccugcgggcugAGCGCGGGCUGAGCGCUGCCAGUCagcgcucacauuaaggcUGACAGCGCCCUGCCUGGCUCggccggcgaagcuc -----------------AGCGCGGGCUGAGCGCUGCC-------------------------------------------------------- 2 0,-4 -----------------AGCGCGGGCUGAGCGCUGCCAGU----------------------------------------------------- 25 0,-1 -----------------AGCGCGGGCUGAGCGCUGCCAGUu---------------------------------------------------- 2 0,-1 -----------------AGCGCGGGCUGAGCGCUGCCAGUC---------------------------------------------------- 4 0,0 -----------------AGCGCGGGCUGAGCGCUGCCAGUCA--------------------------------------------------- 2 0,1 ----------------------------------------------------------UGACAGCGCCCUGCCUGGCUCG------------- 2 0,1 >hsa-mir-2278 5pM:16-37 Tumor gugcugcagguguugGAGAGCAGUGUGUGUUGCCUGGggacuguguggacugguaucacccagacagcuugcacugacuccagacccugccgucau ---------------GAGAGCAGUGUGUGUUGCCUGGa---------------------------------------------------------- 2 0,0 >hsa-mir-2355 5p:11-31;3p:54-75 Tumor cagacgugucAUCCCCAGAUACAAUGGACAAuaugcuauuauaaucguauggcAUUGUCCUUGCUGUUUGGAGAUaauacugcugac ----------AUCCCCAGAUACAAUGGAC---------------------------------------------------------- 8 0,-2 ----------AUCCCCAGAUACAAUGGACA--------------------------------------------------------- 11 0,-1 ----------AUCCCCAGAUACAAUGGACAA-------------------------------------------------------- 11 0,0 ----------AUCCCCAGAUACAAUGGACAAU------------------------------------------------------- 217 0,1 ----------AUCCCCAGAUACAAUGGACAAUA------------------------------------------------------ 2 0,2 -----------------------------------------------------AUUGUCCUUGCUGUUUGGAGA------------- 6 0,-1 -----------------------------------------------------AUUGUCCUUGCUGUUUGGAGAU------------ 32 0,0 -----------------------------------------------------AUUGUCCUUGCUGUUUGGAGAUu----------- 2 0,0 ------------------------------------------------------UUGUCCUUGCUGUUUGGAGA------------- 2 1,-1 ------------------------------------------------------UUGUCCUUGCUGUUUGGAGAU------------ 2 1,0 ------------------------------------------------------UUGUCCUUGCUGUUUGGAGAUA----------- 2 1,1 -------------------------------------------------------UGUCCUUGCUGUUUGGAGAU------------ 22 2,0 -------------------------------------------------------UGUCCUUGCUGUUUGGAGAUA----------- 26 2,1 -------------------------------------------------------UGUCCUUGCUGUUUGGAGAUAc---------- 2 2,1 -------------------------------------------------------UGUCCUUGCUGUUUGGAGAUAA---------- 18 2,2 >hsa-mir-23a mi:9-30;MA:45-65 Tumor ggccggcuGGGGUUCCUGGGGAUGGGAUUUgcuuccugucacaaAUCACAUUGCCAGGGAUUUCCaaccgacc -------UGGGGUUCCUGGGGAUGGGAU--------------------------------------------- 4 -1,-2 -------UGGGGUUCCUGGGGAUGGGAUU-------------------------------------------- 3 -1,-1 --------GGGGUUCCUGGGGAUGGGAU--------------------------------------------- 4 0,-2 --------GGGGUUCCUGGGGAUGGGAUU-------------------------------------------- 62 0,-1 --------GGGGUUCCUGGGGAUGGGAUUU------------------------------------------- 118 0,0 -------------------------------------------AAUCACAUUGCCAGGGAU------------ 54 -1,-4 -------------------------------------------AAUCACAUUGCCAGGGAUa----------- 7 -1,-4 -------------------------------------------AAUCACAUUGCCAGGGAUaa---------- 2 -1,-4 -------------------------------------------AAUCACAUUGCCAGGGAUc----------- 2 -1,-4 -------------------------------------------AAUCACAUUGCCAGGGAUU----------- 457 -1,-3 -------------------------------------------AAUCACAUUGCCAGGGAUUU---------- 429 -1,-2 -------------------------------------------AAUCACAUUGCCAGGGAUUUa--------- 14 -1,-2 -------------------------------------------AAUCACAUUGCCAGGGAUUUaa-------- 2 -1,-2 -------------------------------------------AAUCACAUUGCCAGGGAUUUu--------- 2 -1,-2 -------------------------------------------AAUCACAUUGCCAGGGAUUUC--------- 392 -1,-1 -------------------------------------------AAUCACAUUGCCAGGGAUUUCa-------- 23 -1,-1 -------------------------------------------AAUCACAUUGCCAGGGAUUUCu-------- 2 -1,-1 -------------------------------------------AAUCACAUUGCCAGGGAUUUCC-------- 575 -1,0 -------------------------------------------AAUCACAUUGCCAGGGAUUUCCu------- 2 -1,0 -------------------------------------------AAUCACAUUGCCAGGGAUUUCCA------- 358 -1,1 -------------------------------------------AAUCACAUUGCCAGGGAUUUCCAu------ 4 -1,1 -------------------------------------------AAUCACAUUGCCAGGGAUUUCCAA------ 21 -1,2 -------------------------------------------AAUCACAUUGCCAGGGAUUUCCAAu----- 3 -1,2 --------------------------------------------AUCACAUUGCCAGGGAUU----------- 17897 0,-3 --------------------------------------------AUCACAUUGCCAGGGAUUc---------- 53 0,-3 --------------------------------------------AUCACAUUGCCAGGGAUUg---------- 80 0,-3 --------------------------------------------AUCACAUUGCCAGGGAUUU---------- 45479 0,-2 --------------------------------------------AUCACAUUGCCAGGGAUUUa--------- 3602 0,-2 --------------------------------------------AUCACAUUGCCAGGGAUUUaa-------- 2148 0,-2 --------------------------------------------AUCACAUUGCCAGGGAUUUau-------- 220 0,-2 --------------------------------------------AUCACAUUGCCAGGGAUUUg--------- 288 0,-2 --------------------------------------------AUCACAUUGCCAGGGAUUUu--------- 4014 0,-2 --------------------------------------------AUCACAUUGCCAGGGAUUUuu-------- 178 0,-2 --------------------------------------------AUCACAUUGCCAGGGAUUUC--------- 63961 0,-1 --------------------------------------------AUCACAUUGCCAGGGAUUUCa-------- 5235 0,-1 --------------------------------------------AUCACAUUGCCAGGGAUUUCaa------- 633 0,-1 --------------------------------------------AUCACAUUGCCAGGGAUUUCau------- 14 0,-1 --------------------------------------------AUCACAUUGCCAGGGAUUUCg-------- 197 0,-1 --------------------------------------------AUCACAUUGCCAGGGAUUUCu-------- 1944 0,-1 --------------------------------------------AUCACAUUGCCAGGGAUUUCuu------- 2 0,-1 --------------------------------------------AUCACAUUGCCAGGGAUUUCC-------- 95569 0,0 --------------------------------------------AUCACAUUGCCAGGGAUUUCCc------- 1286 0,0 --------------------------------------------AUCACAUUGCCAGGGAUUUCCg------- 186 0,0 --------------------------------------------AUCACAUUGCCAGGGAUUUCCu------- 752 0,0 --------------------------------------------AUCACAUUGCCAGGGAUUUCCuu------ 92 0,0 --------------------------------------------AUCACAUUGCCAGGGAUUUCCA------- 119752 0,1 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAc------ 258 0,1 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAg------ 507 0,1 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAu------ 9120 0,1 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAuu----- 810 0,1 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAA------ 23733 0,2 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAAa----- 1123 0,2 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAAaa---- 41 0,2 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAAau---- 12 0,2 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAAg----- 85 0,2 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAAu----- 7008 0,2 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAAuu---- 198 0,2 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAAC----- 332 0,3 --------------------------------------------AUCACAUUGCCAGGGAUUUCCAACu---- 7 0,3 ---------------------------------------------UCACAUUGCCAGGGAUUU---------- 66 1,-2 ---------------------------------------------UCACAUUGCCAGGGAUUUa--------- 14 1,-2 ---------------------------------------------UCACAUUGCCAGGGAUUUaa-------- 10 1,-2 ---------------------------------------------UCACAUUGCCAGGGAUUUu--------- 6 1,-2 ---------------------------------------------UCACAUUGCCAGGGAUUUC--------- 198 1,-1 ---------------------------------------------UCACAUUGCCAGGGAUUUCa-------- 16 1,-1 ---------------------------------------------UCACAUUGCCAGGGAUUUCC-------- 294 1,0 ---------------------------------------------UCACAUUGCCAGGGAUUUCCu------- 2 1,0 ---------------------------------------------UCACAUUGCCAGGGAUUUCCA------- 504 1,1 ---------------------------------------------UCACAUUGCCAGGGAUUUCCAu------ 19 1,1 ---------------------------------------------UCACAUUGCCAGGGAUUUCCAuu----- 9 1,1 ---------------------------------------------UCACAUUGCCAGGGAUUUCCAA------ 184 1,2 ---------------------------------------------UCACAUUGCCAGGGAUUUCCAAa----- 2 1,2 ---------------------------------------------UCACAUUGCCAGGGAUUUCCAAg----- 2 1,2 ---------------------------------------------UCACAUUGCCAGGGAUUUCCAAu----- 83 1,2 ---------------------------------------------UCACAUUGCCAGGGAUUUCCAAuu---- 2 1,2 ---------------------------------------------UCACAUUGCCAGGGAUUUCCAAC----- 340 1,3 ---------------------------------------------UCACAUUGCCAGGGAUUUCCAACu---- 7 1,3 ----------------------------------------------CACAUUGCCAGGGAUUUC--------- 59 2,-1 ----------------------------------------------CACAUUGCCAGGGAUUUCC-------- 67 2,0 ----------------------------------------------CACAUUGCCAGGGAUUUCCA------- 106 2,1 ----------------------------------------------CACAUUGCCAGGGAUUUCCAu------ 4 2,1 ----------------------------------------------CACAUUGCCAGGGAUUUCCAA------ 24 2,2 ----------------------------------------------CACAUUGCCAGGGAUUUCCAAu----- 3 2,2 ----------------------------------------------CACAUUGCCAGGGAUUUCCAAC----- 2 2,3 >hsa-mir-23b mi:20-41;MA:58-78 Tumor cucaggugcucuggcugcuUGGGUUCCUGGCAUGCUGAUUUgugacuuaagauuaaaAUCACAUUGCCAGGGAUUACCacgcaaccacgaccuuggc ------------------UUGGGUUCCUGGCAUGCUGAU---------------------------------------------------------- 2 -1,-2 ------------------UUGGGUUCCUGGCAUGCUGAUU--------------------------------------------------------- 2 -1,-1 -------------------UGGGUUCCUGGCAUGCUGA----------------------------------------------------------- 2 0,-3 -------------------UGGGUUCCUGGCAUGCUGAU---------------------------------------------------------- 5 0,-2 -------------------UGGGUUCCUGGCAUGCUGAUU--------------------------------------------------------- 32 0,-1 -------------------UGGGUUCCUGGCAUGCUGAUUU-------------------------------------------------------- 33 0,0 -------------------UGGGUUCCUGGCAUGCUGAUUUu------------------------------------------------------- 2 0,0 --------------------GGGUUCCUGGCAUGCUGAUUU-------------------------------------------------------- 5 1,0 --------------------GGGUUCCUGGCAUGCUGAUUUu------------------------------------------------------- 2 1,0 --------------------------------------------------------AAUCACAUUGCCAGGGAU----------------------- 54 -1,-4 --------------------------------------------------------AAUCACAUUGCCAGGGAUa---------------------- 7 -1,-4 --------------------------------------------------------AAUCACAUUGCCAGGGAUaa--------------------- 2 -1,-4 --------------------------------------------------------AAUCACAUUGCCAGGGAUc---------------------- 2 -1,-4 --------------------------------------------------------AAUCACAUUGCCAGGGAUU---------------------- 457 -1,-3 --------------------------------------------------------AAUCACAUUGCCAGGGAUUA--------------------- 21 -1,-2 --------------------------------------------------------AAUCACAUUGCCAGGGAUUAa-------------------- 4 -1,-2 --------------------------------------------------------AAUCACAUUGCCAGGGAUUAC-------------------- 48 -1,-1 --------------------------------------------------------AAUCACAUUGCCAGGGAUUACC------------------- 109 -1,0 --------------------------------------------------------AAUCACAUUGCCAGGGAUUACCA------------------ 18 -1,1 --------------------------------------------------------AAUCACAUUGCCAGGGAUUACCACu---------------- 8 -1,2 ---------------------------------------------------------AUCACAUUGCCAGGGAUU---------------------- 17897 0,-3 ---------------------------------------------------------AUCACAUUGCCAGGGAUUc--------------------- 53 0,-3 ---------------------------------------------------------AUCACAUUGCCAGGGAUUg--------------------- 80 0,-3 ---------------------------------------------------------AUCACAUUGCCAGGGAUUA--------------------- 4128 0,-2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUAa-------------------- 1884 0,-2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUAaa------------------- 880 0,-2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUAau------------------- 43 0,-2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUAg-------------------- 163 0,-2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUAu-------------------- 776 0,-2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUAuu------------------- 30 0,-2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUAC-------------------- 8950 0,-1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACa------------------- 1168 0,-1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACaa------------------ 118 0,-1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACg------------------- 22 0,-1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACu------------------- 284 0,-1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACuu------------------ 4 0,-1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACC------------------- 23125 0,0 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCc------------------ 144 0,0 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCg------------------ 12 0,0 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCu------------------ 182 0,0 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCuu----------------- 95 0,0 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCA------------------ 18846 0,1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCAa----------------- 306 0,1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCAaa---------------- 4 0,1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCAau---------------- 40 0,1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCAg----------------- 17 0,1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCAu----------------- 2680 0,1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCAuu---------------- 924 0,1 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCAC----------------- 7780 0,2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCACa---------------- 391 0,2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCACc---------------- 135 0,2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCACu---------------- 9961 0,2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCACuu--------------- 30 0,2 ---------------------------------------------------------AUCACAUUGCCAGGGAUUACCACG---------------- 30 0,3 ----------------------------------------------------------UCACAUUGCCAGGGAUUA--------------------- 15 1,-2 ----------------------------------------------------------UCACAUUGCCAGGGAUUAa-------------------- 4 1,-2 ----------------------------------------------------------UCACAUUGCCAGGGAUUAC-------------------- 47 1,-1 ----------------------------------------------------------UCACAUUGCCAGGGAUUACC------------------- 142 1,0 ----------------------------------------------------------UCACAUUGCCAGGGAUUACCA------------------ 166 1,1 ----------------------------------------------------------UCACAUUGCCAGGGAUUACCAu----------------- 21 1,1 ----------------------------------------------------------UCACAUUGCCAGGGAUUACCAuu---------------- 49 1,1 ----------------------------------------------------------UCACAUUGCCAGGGAUUACCAC----------------- 75 1,2 ----------------------------------------------------------UCACAUUGCCAGGGAUUACCACa---------------- 39 1,2 ----------------------------------------------------------UCACAUUGCCAGGGAUUACCACau--------------- 2 1,2 ----------------------------------------------------------UCACAUUGCCAGGGAUUACCACu---------------- 586 1,2 ----------------------------------------------------------UCACAUUGCCAGGGAUUACCACuu--------------- 13 1,2 -----------------------------------------------------------CACAUUGCCAGGGAUUAC-------------------- 2 2,-1 -----------------------------------------------------------CACAUUGCCAGGGAUUACC------------------- 8 2,0 -----------------------------------------------------------CACAUUGCCAGGGAUUACCA------------------ 6 2,1 -----------------------------------------------------------CACAUUGCCAGGGAUUACCAC----------------- 2 2,2 -----------------------------------------------------------CACAUUGCCAGGGAUUACCACu---------------- 9 2,2 >hsa-mir-23c 3pM:66-87 Tumor agugacuuuccaggugucacacagugaguggcauaaucagaguacaauuugagucaugcccauacAUCACAUUGCCAGUGAUUACCCaaggaaagugacg -----------------------------------------------------------------AUCACAUUGCCAGUGAUU----------------- 158 0,-4 -----------------------------------------------------------------AUCACAUUGCCAGUGAUUu---------------- 10 0,-4 -----------------------------------------------------------------AUCACAUUGCCAGUGAUUAC--------------- 2 0,-2 -----------------------------------------------------------------AUCACAUUGCCAGUGAUUACC-------------- 8 0,-1 -----------------------------------------------------------------AUCACAUUGCCAGUGAUUACCa------------- 11 0,-1 >hsa-mir-24-1 mi:7-28;MA:44-65 Tumor cuccggUGCCUACUGAGCUGAUAUCAGUucucauuuuacacacUGGCUCAGUUCAGCAGGAACAGgag ----GGUGCCUACUGAGCUGAUAU-------------------------------------------- 2 -2,-4 ----GGUGCCUACUGAGCUGAUAUC------------------------------------------- 6 -2,-3 ----GGUGCCUACUGAGCUGAUAUCA------------------------------------------ 40 -2,-2 ----GGUGCCUACUGAGCUGAUAUCAG----------------------------------------- 4 -2,-1 ----GGUGCCUACUGAGCUGAUAUCAGU---------------------------------------- 8 -2,0 -----GUGCCUACUGAGCUGAUAUC------------------------------------------- 21 -1,-3 -----GUGCCUACUGAGCUGAUAUCc------------------------------------------ 2 -1,-3 -----GUGCCUACUGAGCUGAUAUCA------------------------------------------ 192 -1,-2 -----GUGCCUACUGAGCUGAUAUCAG----------------------------------------- 88 -1,-1 -----GUGCCUACUGAGCUGAUAUCAGU---------------------------------------- 317 -1,0 ------UGCCUACUGAGCUGAUAUCA------------------------------------------ 28 0,-2 ------UGCCUACUGAGCUGAUAUCAG----------------------------------------- 9 0,-1 ------UGCCUACUGAGCUGAUAUCAGU---------------------------------------- 134 0,0 ------UGCCUACUGAGCUGAUAUCAGUU--------------------------------------- 5 0,1 -----------------------------------------ACUGGCUCAGUUCAGCAGGA------- 53 -2,-4 -----------------------------------------ACUGGCUCAGUUCAGCAGGAA------ 102 -2,-3 -----------------------------------------ACUGGCUCAGUUCAGCAGGAAa----- 37 -2,-3 -----------------------------------------ACUGGCUCAGUUCAGCAGGAAu----- 37 -2,-3 -----------------------------------------ACUGGCUCAGUUCAGCAGGAAC----- 141 -2,-2 -----------------------------------------ACUGGCUCAGUUCAGCAGGAACu---- 4 -2,-2 -----------------------------------------ACUGGCUCAGUUCAGCAGGAACAG--- 2 -2,0 ------------------------------------------CUGGCUCAGUUCAGCAGG-------- 2 -1,-5 ------------------------------------------CUGGCUCAGUUCAGCAGGA------- 7 -1,-4 ------------------------------------------CUGGCUCAGUUCAGCAGGAA------ 114 -1,-3 ------------------------------------------CUGGCUCAGUUCAGCAGGAAa----- 108 -1,-3 ------------------------------------------CUGGCUCAGUUCAGCAGGAAaa---- 4 -1,-3 ------------------------------------------CUGGCUCAGUUCAGCAGGAAg----- 2 -1,-3 ------------------------------------------CUGGCUCAGUUCAGCAGGAAu----- 13 -1,-3 ------------------------------------------CUGGCUCAGUUCAGCAGGAAC----- 446 -1,-2 ------------------------------------------CUGGCUCAGUUCAGCAGGAACu---- 2 -1,-2 ------------------------------------------CUGGCUCAGUUCAGCAGGAACA---- 236 -1,-1 ------------------------------------------CUGGCUCAGUUCAGCAGGAACAa--- 21 -1,-1 ------------------------------------------CUGGCUCAGUUCAGCAGGAACAaa-- 2 -1,-1 ------------------------------------------CUGGCUCAGUUCAGCAGGAACAG--- 625 -1,0 ------------------------------------------CUGGCUCAGUUCAGCAGGAACAGa-- 181 -1,0 ------------------------------------------CUGGCUCAGUUCAGCAGGAACAGaa- 2 -1,0 ------------------------------------------CUGGCUCAGUUCAGCAGGAACAGu-- 1001 -1,0 ------------------------------------------CUGGCUCAGUUCAGCAGGAACAGuu- 17 -1,0 -------------------------------------------UGGCUCAGUUCAGCAGGA------- 6576 0,-4 -------------------------------------------UGGCUCAGUUCAGCAGGAc------ 38 0,-4 -------------------------------------------UGGCUCAGUUCAGCAGGAg------ 182 0,-4 -------------------------------------------UGGCUCAGUUCAGCAGGAu------ 832 0,-4 -------------------------------------------UGGCUCAGUUCAGCAGGAuu----- 195 0,-4 -------------------------------------------UGGCUCAGUUCAGCAGGAA------ 22998 0,-3 -------------------------------------------UGGCUCAGUUCAGCAGGAAa----- 19403 0,-3 -------------------------------------------UGGCUCAGUUCAGCAGGAAaa---- 2065 0,-3 -------------------------------------------UGGCUCAGUUCAGCAGGAAau---- 637 0,-3 -------------------------------------------UGGCUCAGUUCAGCAGGAAg----- 924 0,-3 -------------------------------------------UGGCUCAGUUCAGCAGGAAu----- 5922 0,-3 -------------------------------------------UGGCUCAGUUCAGCAGGAAuu---- 126 0,-3 -------------------------------------------UGGCUCAGUUCAGCAGGAAC----- 90363 0,-2 -------------------------------------------UGGCUCAGUUCAGCAGGAACc---- 263 0,-2 -------------------------------------------UGGCUCAGUUCAGCAGGAACg---- 155 0,-2 -------------------------------------------UGGCUCAGUUCAGCAGGAACu---- 1256 0,-2 -------------------------------------------UGGCUCAGUUCAGCAGGAACuu--- 61 0,-2 -------------------------------------------UGGCUCAGUUCAGCAGGAACA---- 35516 0,-1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAa--- 5455 0,-1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAaa-- 1109 0,-1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAau-- 908 0,-1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAc--- 427 0,-1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAu--- 1238 0,-1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAuu-- 406 0,-1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAG--- 135843 0,0 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGa-- 40118 0,0 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGaa- 1312 0,0 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGau- 723 0,0 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGc-- 1245 0,0 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGu-- 202118 0,0 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGuu- 6426 0,0 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGG-- 1057 0,1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGGu- 79 0,1 -------------------------------------------UGGCUCAGUUCAGCAGGAACAGGA- 46 0,2 --------------------------------------------GGCUCAGUUCAGCAGGAA------ 722 1,-3 --------------------------------------------GGCUCAGUUCAGCAGGAAa----- 749 1,-3 --------------------------------------------GGCUCAGUUCAGCAGGAAaa---- 54 1,-3 --------------------------------------------GGCUCAGUUCAGCAGGAAau---- 2 1,-3 --------------------------------------------GGCUCAGUUCAGCAGGAAg----- 22 1,-3 --------------------------------------------GGCUCAGUUCAGCAGGAAu----- 203 1,-3 --------------------------------------------GGCUCAGUUCAGCAGGAAuu---- 2 1,-3 --------------------------------------------GGCUCAGUUCAGCAGGAAC----- 3699 1,-2 --------------------------------------------GGCUCAGUUCAGCAGGAACc---- 2 1,-2 --------------------------------------------GGCUCAGUUCAGCAGGAACu---- 22 1,-2 --------------------------------------------GGCUCAGUUCAGCAGGAACA---- 1359 1,-1 --------------------------------------------GGCUCAGUUCAGCAGGAACAa--- 188 1,-1 --------------------------------------------GGCUCAGUUCAGCAGGAACAaa-- 18 1,-1 --------------------------------------------GGCUCAGUUCAGCAGGAACAau-- 9 1,-1 --------------------------------------------GGCUCAGUUCAGCAGGAACAc--- 7 1,-1 --------------------------------------------GGCUCAGUUCAGCAGGAACAu--- 15 1,-1 --------------------------------------------GGCUCAGUUCAGCAGGAACAuu-- 6 1,-1 --------------------------------------------GGCUCAGUUCAGCAGGAACAG--- 5512 1,0 --------------------------------------------GGCUCAGUUCAGCAGGAACAGa-- 1713 1,0 --------------------------------------------GGCUCAGUUCAGCAGGAACAGaa- 33 1,0 --------------------------------------------GGCUCAGUUCAGCAGGAACAGau- 8 1,0 --------------------------------------------GGCUCAGUUCAGCAGGAACAGc-- 27 1,0 --------------------------------------------GGCUCAGUUCAGCAGGAACAGu-- 8390 1,0 --------------------------------------------GGCUCAGUUCAGCAGGAACAGuu- 222 1,0 --------------------------------------------GGCUCAGUUCAGCAGGAACAGG-- 29 1,1 --------------------------------------------GGCUCAGUUCAGCAGGAACAGGu- 3 1,1 ---------------------------------------------GCUCAGUUCAGCAGGAAC----- 13 2,-2 ---------------------------------------------GCUCAGUUCAGCAGGAACA---- 2 2,-1 ---------------------------------------------GCUCAGUUCAGCAGGAACAG--- 38 2,0 ---------------------------------------------GCUCAGUUCAGCAGGAACAGa-- 35 2,0 ---------------------------------------------GCUCAGUUCAGCAGGAACAGaa- 9 2,0 ---------------------------------------------GCUCAGUUCAGCAGGAACAGu-- 182 2,0 ---------------------------------------------GCUCAGUUCAGCAGGAACAGuu- 176 2,0 ---------------------------------------------GCUCAGUUCAGCAGGAACAGG-- 20 2,1 ---------------------------------------------GCUCAGUUCAGCAGGAACAGGu- 31 2,1 ---------------------------------------------GCUCAGUUCAGCAGGAACAGGA- 24 2,2 >hsa-mir-24-2 mi:13-34;MA:50-71 Tumor cucugccucccgUGCCUACUGAGCUGAAACACAGuugguuuguguacacUGGCUCAGUUCAGCAGGAACAGgg ----------CGUGCCUACUGAGCUGAAACA------------------------------------------ 4 -2,-3 ----------CGUGCCUACUGAGCUGAAACACA---------------------------------------- 5 -2,-1 ----------CGUGCCUACUGAGCUGAAACACAGU-------------------------------------- 2 -2,1 -----------GUGCCUACUGAGCUGAAA-------------------------------------------- 19 -1,-5 -----------GUGCCUACUGAGCUGAAAa------------------------------------------- 2 -1,-5 -----------GUGCCUACUGAGCUGAAAC------------------------------------------- 65 -1,-4 -----------GUGCCUACUGAGCUGAAACA------------------------------------------ 532 -1,-3 -----------GUGCCUACUGAGCUGAAACAa----------------------------------------- 4 -1,-3 -----------GUGCCUACUGAGCUGAAACAC----------------------------------------- 1139 -1,-2 -----------GUGCCUACUGAGCUGAAACACc---------------------------------------- 6 -1,-2 -----------GUGCCUACUGAGCUGAAACACA---------------------------------------- 2468 -1,-1 -----------GUGCCUACUGAGCUGAAACACAa--------------------------------------- 17 -1,-1 -----------GUGCCUACUGAGCUGAAACACAG--------------------------------------- 1216 -1,0 -----------GUGCCUACUGAGCUGAAACACAGa-------------------------------------- 8 -1,0 -----------GUGCCUACUGAGCUGAAACACAGc-------------------------------------- 4 -1,0 -----------GUGCCUACUGAGCUGAAACACAGU-------------------------------------- 1228 -1,1 -----------GUGCCUACUGAGCUGAAACACAGUa------------------------------------- 2 -1,1 -----------GUGCCUACUGAGCUGAAACACAGUU------------------------------------- 2 -1,2 ------------UGCCUACUGAGCUGAAACA------------------------------------------ 2 0,-3 ------------UGCCUACUGAGCUGAAACAC----------------------------------------- 4 0,-2 ------------UGCCUACUGAGCUGAAACACA---------------------------------------- 15 0,-1 ------------UGCCUACUGAGCUGAAACACAG--------------------------------------- 47 0,0 ------------UGCCUACUGAGCUGAAACACAGU-------------------------------------- 295 0,1 -------------GCCUACUGAGCUGAAACACAG--------------------------------------- 2 1,0 -------------GCCUACUGAGCUGAAACACAGU-------------------------------------- 8 1,1 -----------------------------------------------ACUGGCUCAGUUCAGCAGGA------ 53 -2,-4 -----------------------------------------------ACUGGCUCAGUUCAGCAGGAA----- 102 -2,-3 -----------------------------------------------ACUGGCUCAGUUCAGCAGGAAa---- 37 -2,-3 -----------------------------------------------ACUGGCUCAGUUCAGCAGGAAu---- 37 -2,-3 -----------------------------------------------ACUGGCUCAGUUCAGCAGGAAC---- 141 -2,-2 -----------------------------------------------ACUGGCUCAGUUCAGCAGGAACu--- 4 -2,-2 -----------------------------------------------ACUGGCUCAGUUCAGCAGGAACAG-- 2 -2,0 ------------------------------------------------CUGGCUCAGUUCAGCAGG------- 2 -1,-5 ------------------------------------------------CUGGCUCAGUUCAGCAGGA------ 7 -1,-4 ------------------------------------------------CUGGCUCAGUUCAGCAGGAA----- 114 -1,-3 ------------------------------------------------CUGGCUCAGUUCAGCAGGAAa---- 108 -1,-3 ------------------------------------------------CUGGCUCAGUUCAGCAGGAAaa--- 4 -1,-3 ------------------------------------------------CUGGCUCAGUUCAGCAGGAAg---- 2 -1,-3 ------------------------------------------------CUGGCUCAGUUCAGCAGGAAu---- 13 -1,-3 ------------------------------------------------CUGGCUCAGUUCAGCAGGAAC---- 446 -1,-2 ------------------------------------------------CUGGCUCAGUUCAGCAGGAACu--- 2 -1,-2 ------------------------------------------------CUGGCUCAGUUCAGCAGGAACA--- 236 -1,-1 ------------------------------------------------CUGGCUCAGUUCAGCAGGAACAa-- 21 -1,-1 ------------------------------------------------CUGGCUCAGUUCAGCAGGAACAaa- 2 -1,-1 ------------------------------------------------CUGGCUCAGUUCAGCAGGAACAG-- 625 -1,0 ------------------------------------------------CUGGCUCAGUUCAGCAGGAACAGa- 181 -1,0 ------------------------------------------------CUGGCUCAGUUCAGCAGGAACAGaa 2 -1,0 ------------------------------------------------CUGGCUCAGUUCAGCAGGAACAGu- 1001 -1,0 ------------------------------------------------CUGGCUCAGUUCAGCAGGAACAGuu 17 -1,0 -------------------------------------------------UGGCUCAGUUCAGCAGGA------ 6576 0,-4 -------------------------------------------------UGGCUCAGUUCAGCAGGAc----- 38 0,-4 -------------------------------------------------UGGCUCAGUUCAGCAGGAg----- 182 0,-4 -------------------------------------------------UGGCUCAGUUCAGCAGGAu----- 832 0,-4 -------------------------------------------------UGGCUCAGUUCAGCAGGAuu---- 195 0,-4 -------------------------------------------------UGGCUCAGUUCAGCAGGAA----- 22998 0,-3 -------------------------------------------------UGGCUCAGUUCAGCAGGAAa---- 19403 0,-3 -------------------------------------------------UGGCUCAGUUCAGCAGGAAaa--- 2065 0,-3 -------------------------------------------------UGGCUCAGUUCAGCAGGAAau--- 637 0,-3 -------------------------------------------------UGGCUCAGUUCAGCAGGAAg---- 924 0,-3 -------------------------------------------------UGGCUCAGUUCAGCAGGAAu---- 5922 0,-3 -------------------------------------------------UGGCUCAGUUCAGCAGGAAuu--- 126 0,-3 -------------------------------------------------UGGCUCAGUUCAGCAGGAAC---- 90363 0,-2 -------------------------------------------------UGGCUCAGUUCAGCAGGAACc--- 263 0,-2 -------------------------------------------------UGGCUCAGUUCAGCAGGAACg--- 155 0,-2 -------------------------------------------------UGGCUCAGUUCAGCAGGAACu--- 1256 0,-2 -------------------------------------------------UGGCUCAGUUCAGCAGGAACuu-- 61 0,-2 -------------------------------------------------UGGCUCAGUUCAGCAGGAACA--- 35516 0,-1 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAa-- 5455 0,-1 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAaa- 1109 0,-1 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAau- 908 0,-1 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAc-- 427 0,-1 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAu-- 1238 0,-1 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAuu- 406 0,-1 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAG-- 135843 0,0 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAGa- 40118 0,0 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAGaa 1312 0,0 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAGau 723 0,0 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAGc- 1245 0,0 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAGu- 202118 0,0 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAGuu 6426 0,0 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAGG- 1057 0,1 -------------------------------------------------UGGCUCAGUUCAGCAGGAACAGGu 79 0,1 --------------------------------------------------GGCUCAGUUCAGCAGGAA----- 722 1,-3 --------------------------------------------------GGCUCAGUUCAGCAGGAAa---- 749 1,-3 --------------------------------------------------GGCUCAGUUCAGCAGGAAaa--- 54 1,-3 --------------------------------------------------GGCUCAGUUCAGCAGGAAau--- 2 1,-3 --------------------------------------------------GGCUCAGUUCAGCAGGAAg---- 22 1,-3 --------------------------------------------------GGCUCAGUUCAGCAGGAAu---- 203 1,-3 --------------------------------------------------GGCUCAGUUCAGCAGGAAuu--- 2 1,-3 --------------------------------------------------GGCUCAGUUCAGCAGGAAC---- 3699 1,-2 --------------------------------------------------GGCUCAGUUCAGCAGGAACc--- 2 1,-2 --------------------------------------------------GGCUCAGUUCAGCAGGAACu--- 22 1,-2 --------------------------------------------------GGCUCAGUUCAGCAGGAACA--- 1359 1,-1 --------------------------------------------------GGCUCAGUUCAGCAGGAACAa-- 188 1,-1 --------------------------------------------------GGCUCAGUUCAGCAGGAACAaa- 18 1,-1 --------------------------------------------------GGCUCAGUUCAGCAGGAACAau- 9 1,-1 --------------------------------------------------GGCUCAGUUCAGCAGGAACAc-- 7 1,-1 --------------------------------------------------GGCUCAGUUCAGCAGGAACAu-- 15 1,-1 --------------------------------------------------GGCUCAGUUCAGCAGGAACAuu- 6 1,-1 --------------------------------------------------GGCUCAGUUCAGCAGGAACAG-- 5512 1,0 --------------------------------------------------GGCUCAGUUCAGCAGGAACAGa- 1713 1,0 --------------------------------------------------GGCUCAGUUCAGCAGGAACAGaa 33 1,0 --------------------------------------------------GGCUCAGUUCAGCAGGAACAGau 8 1,0 --------------------------------------------------GGCUCAGUUCAGCAGGAACAGc- 27 1,0 --------------------------------------------------GGCUCAGUUCAGCAGGAACAGu- 8390 1,0 --------------------------------------------------GGCUCAGUUCAGCAGGAACAGuu 222 1,0 --------------------------------------------------GGCUCAGUUCAGCAGGAACAGG- 29 1,1 --------------------------------------------------GGCUCAGUUCAGCAGGAACAGGu 3 1,1 ---------------------------------------------------GCUCAGUUCAGCAGGAAC---- 13 2,-2 ---------------------------------------------------GCUCAGUUCAGCAGGAACA--- 2 2,-1 ---------------------------------------------------GCUCAGUUCAGCAGGAACAG-- 38 2,0 ---------------------------------------------------GCUCAGUUCAGCAGGAACAGa- 35 2,0 ---------------------------------------------------GCUCAGUUCAGCAGGAACAGaa 9 2,0 ---------------------------------------------------GCUCAGUUCAGCAGGAACAGu- 182 2,0 ---------------------------------------------------GCUCAGUUCAGCAGGAACAGuu 176 2,0 ---------------------------------------------------GCUCAGUUCAGCAGGAACAGG- 20 2,1 ---------------------------------------------------GCUCAGUUCAGCAGGAACAGGu 31 2,1 >hsa-mir-25 mi:14-34;MA:52-73 Tumor ggccaguguugagAGGCGGAGACUUGGGCAAUUGcuggacgcugcccugggCAUUGCACUUGUCUCGGUCUGAcagugccggcc -------------AGGCGGAGACUUGGGCAAUUGC------------------------------------------------- 8 0,1 -------------AGGCGGAGACUUGGGCAAUUGCU------------------------------------------------ 28 0,2 --------------------------------------------------GCAUUGCACUUGUCUCGGUCUGA----------- 2 -1,0 ---------------------------------------------------CAUUGCACUUGUCUCGGU--------------- 321 0,-4 ---------------------------------------------------CAUUGCACUUGUCUCGGUa-------------- 33 0,-4 ---------------------------------------------------CAUUGCACUUGUCUCGGUaa------------- 21 0,-4 ---------------------------------------------------CAUUGCACUUGUCUCGGUau------------- 4 0,-4 ---------------------------------------------------CAUUGCACUUGUCUCGGUu-------------- 22 0,-4 ---------------------------------------------------CAUUGCACUUGUCUCGGUC-------------- 366 0,-3 ---------------------------------------------------CAUUGCACUUGUCUCGGUCa------------- 80 0,-3 ---------------------------------------------------CAUUGCACUUGUCUCGGUCaa------------ 7 0,-3 ---------------------------------------------------CAUUGCACUUGUCUCGGUCU------------- 4190 0,-2 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUa------------ 7 0,-2 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUaa----------- 148 0,-2 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUau----------- 9 0,-2 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUu------------ 50 0,-2 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUuu----------- 56 0,-2 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUG------------ 3244 0,-1 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGc----------- 766 0,-1 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGg----------- 69 0,-1 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGu----------- 3560 0,-1 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGuu---------- 97 0,-1 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGA----------- 73288 0,0 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGAa---------- 1970 0,0 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGAaa--------- 273 0,0 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGAau--------- 160 0,0 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGAg---------- 99 0,0 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGAu---------- 1743 0,0 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGAuu--------- 66 0,0 ---------------------------------------------------CAUUGCACUUGUCUCGGUCUGAC---------- 12 0,1 ----------------------------------------------------AUUGCACUUGUCUCGGUC-------------- 3 1,-3 ----------------------------------------------------AUUGCACUUGUCUCGGUCU------------- 111 1,-2 ----------------------------------------------------AUUGCACUUGUCUCGGUCUaa----------- 2 1,-2 ----------------------------------------------------AUUGCACUUGUCUCGGUCUG------------ 112 1,-1 ----------------------------------------------------AUUGCACUUGUCUCGGUCUGc----------- 28 1,-1 ----------------------------------------------------AUUGCACUUGUCUCGGUCUGu----------- 105 1,-1 ----------------------------------------------------AUUGCACUUGUCUCGGUCUGA----------- 3224 1,0 ----------------------------------------------------AUUGCACUUGUCUCGGUCUGAa---------- 54 1,0 ----------------------------------------------------AUUGCACUUGUCUCGGUCUGAaa--------- 8 1,0 ----------------------------------------------------AUUGCACUUGUCUCGGUCUGAu---------- 34 1,0 -----------------------------------------------------UUGCACUUGUCUCGGUCUGu----------- 2 2,-1 -----------------------------------------------------UUGCACUUGUCUCGGUCUGA----------- 25 2,0 >hsa-mir-2682 MA:23-45;mi:60-81 Tumor accuuccugaaagagguuggggCAGGCAGUGACUGUUCAGACGUCcaaucucuuugggaCGCCUCUUCAGCGCUGUCUUCCcugccucugccuuuaggacgagucucaaa ----------------------CAGGCAGUGACUGUUCAGACGU------------------------------------------------------------------ 3 0,-1 ----------------------CAGGCAGUGACUGUUCAGACGUC----------------------------------------------------------------- 2 0,0 ----------------------------------------------------------ACGCCUCUUCAGCGCUGUCU-------------------------------- 2 -1,-3 >hsa-mir-26a-1 MA:10-31;mi:49-70 Tumor guggccucgUUCAAGUAAUCCAGGAUAGGCUgugcaggucccaaugggCCUAUUCUUGGUUACUUGCACGgggacgc --------GUUCAAGUAAUCCAGGAUAGGCU---------------------------------------------- 8 -1,0 ---------UUCAAGUAAUCCAGGAUA-------------------------------------------------- 3726 0,-4 ---------UUCAAGUAAUCCAGGAUAa------------------------------------------------- 660 0,-4 ---------UUCAAGUAAUCCAGGAUAaa------------------------------------------------ 328 0,-4 ---------UUCAAGUAAUCCAGGAUAau------------------------------------------------ 9 0,-4 ---------UUCAAGUAAUCCAGGAUAu------------------------------------------------- 57 0,-4 ---------UUCAAGUAAUCCAGGAUAG------------------------------------------------- 11379 0,-3 ---------UUCAAGUAAUCCAGGAUAGa------------------------------------------------ 2766 0,-3 ---------UUCAAGUAAUCCAGGAUAGaa----------------------------------------------- 385 0,-3 ---------UUCAAGUAAUCCAGGAUAGau----------------------------------------------- 17 0,-3 ---------UUCAAGUAAUCCAGGAUAGc------------------------------------------------ 5 0,-3 ---------UUCAAGUAAUCCAGGAUAGu------------------------------------------------ 543 0,-3 ---------UUCAAGUAAUCCAGGAUAGuu----------------------------------------------- 3 0,-3 ---------UUCAAGUAAUCCAGGAUAGG------------------------------------------------ 65183 0,-2 ---------UUCAAGUAAUCCAGGAUAGGa----------------------------------------------- 13414 0,-2 ---------UUCAAGUAAUCCAGGAUAGGaa---------------------------------------------- 7188 0,-2 ---------UUCAAGUAAUCCAGGAUAGGau---------------------------------------------- 1247 0,-2 ---------UUCAAGUAAUCCAGGAUAGGg----------------------------------------------- 68 0,-2 ---------UUCAAGUAAUCCAGGAUAGGu----------------------------------------------- 2054 0,-2 ---------UUCAAGUAAUCCAGGAUAGGuu---------------------------------------------- 753 0,-2 ---------UUCAAGUAAUCCAGGAUAGGC----------------------------------------------- 96560 0,-1 ---------UUCAAGUAAUCCAGGAUAGGCa---------------------------------------------- 12767 0,-1 ---------UUCAAGUAAUCCAGGAUAGGCaa--------------------------------------------- 3572 0,-1 ---------UUCAAGUAAUCCAGGAUAGGCau--------------------------------------------- 2628 0,-1 ---------UUCAAGUAAUCCAGGAUAGGCc---------------------------------------------- 770 0,-1 ---------UUCAAGUAAUCCAGGAUAGGCg---------------------------------------------- 467 0,-1 ---------UUCAAGUAAUCCAGGAUAGGCU---------------------------------------------- 361554 0,0 ---------UUCAAGUAAUCCAGGAUAGGCUa--------------------------------------------- 12037 0,0 ---------UUCAAGUAAUCCAGGAUAGGCUaa-------------------------------------------- 1423 0,0 ---------UUCAAGUAAUCCAGGAUAGGCUau-------------------------------------------- 3068 0,0 ---------UUCAAGUAAUCCAGGAUAGGCUc--------------------------------------------- 176 0,0 ---------UUCAAGUAAUCCAGGAUAGGCUu--------------------------------------------- 33425 0,0 ---------UUCAAGUAAUCCAGGAUAGGCUuu-------------------------------------------- 5203 0,0 ---------UUCAAGUAAUCCAGGAUAGGCUG--------------------------------------------- 1299 0,1 ---------UUCAAGUAAUCCAGGAUAGGCUGa-------------------------------------------- 132 0,1 ---------UUCAAGUAAUCCAGGAUAGGCUGaa------------------------------------------- 2 0,1 ---------UUCAAGUAAUCCAGGAUAGGCUGg-------------------------------------------- 18 0,1 ---------UUCAAGUAAUCCAGGAUAGGCUGU-------------------------------------------- 227 0,2 ----------UCAAGUAAUCCAGGAUAG------------------------------------------------- 129 1,-3 ----------UCAAGUAAUCCAGGAUAGa------------------------------------------------ 41 1,-3 ----------UCAAGUAAUCCAGGAUAGaa----------------------------------------------- 3 1,-3 ----------UCAAGUAAUCCAGGAUAGG------------------------------------------------ 1019 1,-2 ----------UCAAGUAAUCCAGGAUAGGa----------------------------------------------- 255 1,-2 ----------UCAAGUAAUCCAGGAUAGGaa---------------------------------------------- 114 1,-2 ----------UCAAGUAAUCCAGGAUAGGau---------------------------------------------- 2 1,-2 ----------UCAAGUAAUCCAGGAUAGGu----------------------------------------------- 24 1,-2 ----------UCAAGUAAUCCAGGAUAGGuu---------------------------------------------- 3 1,-2 ----------UCAAGUAAUCCAGGAUAGGC----------------------------------------------- 1816 1,-1 ----------UCAAGUAAUCCAGGAUAGGCa---------------------------------------------- 250 1,-1 ----------UCAAGUAAUCCAGGAUAGGCaa--------------------------------------------- 43 1,-1 ----------UCAAGUAAUCCAGGAUAGGCau--------------------------------------------- 25 1,-1 ----------UCAAGUAAUCCAGGAUAGGCc---------------------------------------------- 7 1,-1 ----------UCAAGUAAUCCAGGAUAGGCU---------------------------------------------- 7492 1,0 ----------UCAAGUAAUCCAGGAUAGGCUa--------------------------------------------- 225 1,0 ----------UCAAGUAAUCCAGGAUAGGCUaa-------------------------------------------- 17 1,0 ----------UCAAGUAAUCCAGGAUAGGCUau-------------------------------------------- 43 1,0 ----------UCAAGUAAUCCAGGAUAGGCUu--------------------------------------------- 636 1,0 ----------UCAAGUAAUCCAGGAUAGGCUuu-------------------------------------------- 100 1,0 ----------UCAAGUAAUCCAGGAUAGGCUG--------------------------------------------- 36 1,1 -----------CAAGUAAUCCAGGAUAGG------------------------------------------------ 78 2,-2 -----------CAAGUAAUCCAGGAUAGGa----------------------------------------------- 11 2,-2 -----------CAAGUAAUCCAGGAUAGGaa---------------------------------------------- 2 2,-2 -----------CAAGUAAUCCAGGAUAGGC----------------------------------------------- 97 2,-1 -----------CAAGUAAUCCAGGAUAGGCa---------------------------------------------- 3 2,-1 -----------CAAGUAAUCCAGGAUAGGCU---------------------------------------------- 676 2,0 -----------CAAGUAAUCCAGGAUAGGCUa--------------------------------------------- 12 2,0 -----------CAAGUAAUCCAGGAUAGGCUu--------------------------------------------- 36 2,0 ------------------------------------------------CCUAUUCUUGGUUACUUGCACG------- 28 0,0 ------------------------------------------------CCUAUUCUUGGUUACUUGCACGu------ 2 0,0 >hsa-mir-26a-2 MA:14-35;mi:52-73 Tumor ggcuguggcuggaUUCAAGUAAUCCAGGAUAGGCUguuuccaucugugaggCCUAUUCUUGAUUACUUGUUUCuggaggcagcu ------------AUUCAAGUAAUCCAGGAUAGG--------------------------------------------------- 2 -1,-2 ------------AUUCAAGUAAUCCAGGAUAGGC-------------------------------------------------- 2 -1,-1 ------------AUUCAAGUAAUCCAGGAUAGGCU------------------------------------------------- 47 -1,0 ------------AUUCAAGUAAUCCAGGAUAGGCUu------------------------------------------------ 2 -1,0 -------------UUCAAGUAAUCCAGGAUA----------------------------------------------------- 3726 0,-4 -------------UUCAAGUAAUCCAGGAUAa---------------------------------------------------- 660 0,-4 -------------UUCAAGUAAUCCAGGAUAaa--------------------------------------------------- 328 0,-4 -------------UUCAAGUAAUCCAGGAUAau--------------------------------------------------- 9 0,-4 -------------UUCAAGUAAUCCAGGAUAu---------------------------------------------------- 57 0,-4 -------------UUCAAGUAAUCCAGGAUAG---------------------------------------------------- 11379 0,-3 -------------UUCAAGUAAUCCAGGAUAGa--------------------------------------------------- 2766 0,-3 -------------UUCAAGUAAUCCAGGAUAGaa-------------------------------------------------- 385 0,-3 -------------UUCAAGUAAUCCAGGAUAGau-------------------------------------------------- 17 0,-3 -------------UUCAAGUAAUCCAGGAUAGc--------------------------------------------------- 5 0,-3 -------------UUCAAGUAAUCCAGGAUAGu--------------------------------------------------- 543 0,-3 -------------UUCAAGUAAUCCAGGAUAGuu-------------------------------------------------- 3 0,-3 -------------UUCAAGUAAUCCAGGAUAGG--------------------------------------------------- 65183 0,-2 -------------UUCAAGUAAUCCAGGAUAGGa-------------------------------------------------- 13414 0,-2 -------------UUCAAGUAAUCCAGGAUAGGaa------------------------------------------------- 7188 0,-2 -------------UUCAAGUAAUCCAGGAUAGGau------------------------------------------------- 1247 0,-2 -------------UUCAAGUAAUCCAGGAUAGGg-------------------------------------------------- 68 0,-2 -------------UUCAAGUAAUCCAGGAUAGGu-------------------------------------------------- 2054 0,-2 -------------UUCAAGUAAUCCAGGAUAGGuu------------------------------------------------- 753 0,-2 -------------UUCAAGUAAUCCAGGAUAGGC-------------------------------------------------- 96560 0,-1 -------------UUCAAGUAAUCCAGGAUAGGCa------------------------------------------------- 12767 0,-1 -------------UUCAAGUAAUCCAGGAUAGGCaa------------------------------------------------ 3572 0,-1 -------------UUCAAGUAAUCCAGGAUAGGCau------------------------------------------------ 2628 0,-1 -------------UUCAAGUAAUCCAGGAUAGGCc------------------------------------------------- 770 0,-1 -------------UUCAAGUAAUCCAGGAUAGGCg------------------------------------------------- 467 0,-1 -------------UUCAAGUAAUCCAGGAUAGGCU------------------------------------------------- 361554 0,0 -------------UUCAAGUAAUCCAGGAUAGGCUa------------------------------------------------ 12037 0,0 -------------UUCAAGUAAUCCAGGAUAGGCUaa----------------------------------------------- 1423 0,0 -------------UUCAAGUAAUCCAGGAUAGGCUau----------------------------------------------- 3068 0,0 -------------UUCAAGUAAUCCAGGAUAGGCUc------------------------------------------------ 176 0,0 -------------UUCAAGUAAUCCAGGAUAGGCUu------------------------------------------------ 33425 0,0 -------------UUCAAGUAAUCCAGGAUAGGCUuu----------------------------------------------- 5203 0,0 -------------UUCAAGUAAUCCAGGAUAGGCUG------------------------------------------------ 1299 0,1 -------------UUCAAGUAAUCCAGGAUAGGCUGa----------------------------------------------- 132 0,1 -------------UUCAAGUAAUCCAGGAUAGGCUGaa---------------------------------------------- 2 0,1 -------------UUCAAGUAAUCCAGGAUAGGCUGg----------------------------------------------- 18 0,1 -------------UUCAAGUAAUCCAGGAUAGGCUGU----------------------------------------------- 227 0,2 -------------UUCAAGUAAUCCAGGAUAGGCUGUU---------------------------------------------- 6 0,3 --------------UCAAGUAAUCCAGGAUAG---------------------------------------------------- 129 1,-3 --------------UCAAGUAAUCCAGGAUAGa--------------------------------------------------- 41 1,-3 --------------UCAAGUAAUCCAGGAUAGaa-------------------------------------------------- 3 1,-3 --------------UCAAGUAAUCCAGGAUAGG--------------------------------------------------- 1019 1,-2 --------------UCAAGUAAUCCAGGAUAGGa-------------------------------------------------- 255 1,-2 --------------UCAAGUAAUCCAGGAUAGGaa------------------------------------------------- 114 1,-2 --------------UCAAGUAAUCCAGGAUAGGau------------------------------------------------- 2 1,-2 --------------UCAAGUAAUCCAGGAUAGGu-------------------------------------------------- 24 1,-2 --------------UCAAGUAAUCCAGGAUAGGuu------------------------------------------------- 3 1,-2 --------------UCAAGUAAUCCAGGAUAGGC-------------------------------------------------- 1816 1,-1 --------------UCAAGUAAUCCAGGAUAGGCa------------------------------------------------- 250 1,-1 --------------UCAAGUAAUCCAGGAUAGGCaa------------------------------------------------ 43 1,-1 --------------UCAAGUAAUCCAGGAUAGGCau------------------------------------------------ 25 1,-1 --------------UCAAGUAAUCCAGGAUAGGCc------------------------------------------------- 7 1,-1 --------------UCAAGUAAUCCAGGAUAGGCU------------------------------------------------- 7492 1,0 --------------UCAAGUAAUCCAGGAUAGGCUa------------------------------------------------ 225 1,0 --------------UCAAGUAAUCCAGGAUAGGCUaa----------------------------------------------- 17 1,0 --------------UCAAGUAAUCCAGGAUAGGCUau----------------------------------------------- 43 1,0 --------------UCAAGUAAUCCAGGAUAGGCUu------------------------------------------------ 636 1,0 --------------UCAAGUAAUCCAGGAUAGGCUuu----------------------------------------------- 100 1,0 --------------UCAAGUAAUCCAGGAUAGGCUG------------------------------------------------ 36 1,1 ---------------CAAGUAAUCCAGGAUAGG--------------------------------------------------- 78 2,-2 ---------------CAAGUAAUCCAGGAUAGGa-------------------------------------------------- 11 2,-2 ---------------CAAGUAAUCCAGGAUAGGaa------------------------------------------------- 2 2,-2 ---------------CAAGUAAUCCAGGAUAGGC-------------------------------------------------- 97 2,-1 ---------------CAAGUAAUCCAGGAUAGGCa------------------------------------------------- 3 2,-1 ---------------CAAGUAAUCCAGGAUAGGCU------------------------------------------------- 676 2,0 ---------------CAAGUAAUCCAGGAUAGGCUa------------------------------------------------ 12 2,0 ---------------CAAGUAAUCCAGGAUAGGCUu------------------------------------------------ 36 2,0 ---------------------------------------------------CCUAUUCUUGAUUACUUGUU------------- 22 0,-2 ---------------------------------------------------CCUAUUCUUGAUUACUUGUUa------------ 2 0,-2 ---------------------------------------------------CCUAUUCUUGAUUACUUGUUU------------ 93 0,-1 ---------------------------------------------------CCUAUUCUUGAUUACUUGUUUa----------- 4 0,-1 ---------------------------------------------------CCUAUUCUUGAUUACUUGUUUu----------- 7 0,-1 ---------------------------------------------------CCUAUUCUUGAUUACUUGUUUC----------- 250 0,0 ---------------------------------------------------CCUAUUCUUGAUUACUUGUUUCU---------- 2 0,1 ----------------------------------------------------CUAUUCUUGAUUACUUGUUUC----------- 2 1,0 >hsa-mir-26b MA:12-32;mi:47-68 Tumor ccgggacccagUUCAAGUAAUUCAGGAUAGGUugugugcuguccagCCUGUUCUCCAUUACUUGGCUCggggaccgg -----------UUCAAGUAAUUCAGGAUA------------------------------------------------ 791 0,-3 -----------UUCAAGUAAUUCAGGAUAa----------------------------------------------- 156 0,-3 -----------UUCAAGUAAUUCAGGAUAaa---------------------------------------------- 54 0,-3 -----------UUCAAGUAAUUCAGGAUAu----------------------------------------------- 4 0,-3 -----------UUCAAGUAAUUCAGGAUAG----------------------------------------------- 1807 0,-2 -----------UUCAAGUAAUUCAGGAUAGa---------------------------------------------- 313 0,-2 -----------UUCAAGUAAUUCAGGAUAGaa--------------------------------------------- 22 0,-2 -----------UUCAAGUAAUUCAGGAUAGau--------------------------------------------- 70 0,-2 -----------UUCAAGUAAUUCAGGAUAGc---------------------------------------------- 2 0,-2 -----------UUCAAGUAAUUCAGGAUAGu---------------------------------------------- 34 0,-2 -----------UUCAAGUAAUUCAGGAUAGuu--------------------------------------------- 85 0,-2 -----------UUCAAGUAAUUCAGGAUAGG---------------------------------------------- 8795 0,-1 -----------UUCAAGUAAUUCAGGAUAGGa--------------------------------------------- 1983 0,-1 -----------UUCAAGUAAUUCAGGAUAGGaa-------------------------------------------- 823 0,-1 -----------UUCAAGUAAUUCAGGAUAGGau-------------------------------------------- 144 0,-1 -----------UUCAAGUAAUUCAGGAUAGGc--------------------------------------------- 168 0,-1 -----------UUCAAGUAAUUCAGGAUAGGg--------------------------------------------- 101 0,-1 -----------UUCAAGUAAUUCAGGAUAGGU--------------------------------------------- 44275 0,0 -----------UUCAAGUAAUUCAGGAUAGGUa-------------------------------------------- 5137 0,0 -----------UUCAAGUAAUUCAGGAUAGGUaa------------------------------------------- 3582 0,0 -----------UUCAAGUAAUUCAGGAUAGGUau------------------------------------------- 766 0,0 -----------UUCAAGUAAUUCAGGAUAGGUc-------------------------------------------- 157 0,0 -----------UUCAAGUAAUUCAGGAUAGGUg-------------------------------------------- 154 0,0 -----------UUCAAGUAAUUCAGGAUAGGUU-------------------------------------------- 124589 0,1 -----------UUCAAGUAAUUCAGGAUAGGUUa------------------------------------------- 7137 0,1 -----------UUCAAGUAAUUCAGGAUAGGUUaa------------------------------------------ 489 0,1 -----------UUCAAGUAAUUCAGGAUAGGUUau------------------------------------------ 377 0,1 -----------UUCAAGUAAUUCAGGAUAGGUUc------------------------------------------- 59 0,1 -----------UUCAAGUAAUUCAGGAUAGGUUu------------------------------------------- 9260 0,1 -----------UUCAAGUAAUUCAGGAUAGGUUuu------------------------------------------ 259 0,1 -----------UUCAAGUAAUUCAGGAUAGGUUG------------------------------------------- 990 0,2 -----------UUCAAGUAAUUCAGGAUAGGUUGa------------------------------------------ 37 0,2 -----------UUCAAGUAAUUCAGGAUAGGUUGU------------------------------------------ 138 0,3 ------------UCAAGUAAUUCAGGAUAG----------------------------------------------- 12 1,-2 ------------UCAAGUAAUUCAGGAUAGG---------------------------------------------- 81 1,-1 ------------UCAAGUAAUUCAGGAUAGGa--------------------------------------------- 11 1,-1 ------------UCAAGUAAUUCAGGAUAGGaa-------------------------------------------- 6 1,-1 ------------UCAAGUAAUUCAGGAUAGGU--------------------------------------------- 627 1,0 ------------UCAAGUAAUUCAGGAUAGGUa-------------------------------------------- 63 1,0 ------------UCAAGUAAUUCAGGAUAGGUaa------------------------------------------- 28 1,0 ------------UCAAGUAAUUCAGGAUAGGUau------------------------------------------- 2 1,0 ------------UCAAGUAAUUCAGGAUAGGUU-------------------------------------------- 1818 1,1 ------------UCAAGUAAUUCAGGAUAGGUUa------------------------------------------- 87 1,1 ------------UCAAGUAAUUCAGGAUAGGUUaa------------------------------------------ 2 1,1 ------------UCAAGUAAUUCAGGAUAGGUUu------------------------------------------- 134 1,1 ------------UCAAGUAAUUCAGGAUAGGUUuu------------------------------------------ 2 1,1 ------------UCAAGUAAUUCAGGAUAGGUUG------------------------------------------- 5 1,2 -------------CAAGUAAUUCAGGAUAGG---------------------------------------------- 8 2,-1 -------------CAAGUAAUUCAGGAUAGGU--------------------------------------------- 87 2,0 -------------CAAGUAAUUCAGGAUAGGUa-------------------------------------------- 7 2,0 -------------CAAGUAAUUCAGGAUAGGUaa------------------------------------------- 2 2,0 -------------CAAGUAAUUCAGGAUAGGUU-------------------------------------------- 330 2,1 -------------CAAGUAAUUCAGGAUAGGUUa------------------------------------------- 14 2,1 -------------CAAGUAAUUCAGGAUAGGUUu------------------------------------------- 14 2,1 ----------------------------------------------CCUGUUCUCCAUUACUUGG------------ 4 0,-3 ----------------------------------------------CCUGUUCUCCAUUACUUGGC----------- 11 0,-2 ----------------------------------------------CCUGUUCUCCAUUACUUGGCU---------- 222 0,-1 ----------------------------------------------CCUGUUCUCCAUUACUUGGCUa--------- 2 0,-1 ----------------------------------------------CCUGUUCUCCAUUACUUGGCUu--------- 7 0,-1 ----------------------------------------------CCUGUUCUCCAUUACUUGGCUuu-------- 2 0,-1 ----------------------------------------------CCUGUUCUCCAUUACUUGGCUC--------- 49 0,0 ----------------------------------------------CCUGUUCUCCAUUACUUGGCUCu-------- 11 0,0 -----------------------------------------------CUGUUCUCCAUUACUUGGCU---------- 2 1,-1 -----------------------------------------------CUGUUCUCCAUUACUUGGCUCu-------- 2 1,0 >hsa-mir-27a mi:10-31;MA:51-71 Tumor cugaggagcAGGGCUUAGCUGCUUGUGAGCAggguccacaccaagucgugUUCACAGUGGCUAAGUUCCGCcccccag ---------AGGGCUUAGCUGCUUGUG--------------------------------------------------- 4 0,-4 ---------AGGGCUUAGCUGCUUGUGA-------------------------------------------------- 2 0,-3 ---------AGGGCUUAGCUGCUUGUGAG------------------------------------------------- 6 0,-2 ---------AGGGCUUAGCUGCUUGUGAGaa----------------------------------------------- 3 0,-2 ---------AGGGCUUAGCUGCUUGUGAGC------------------------------------------------ 441 0,-1 ---------AGGGCUUAGCUGCUUGUGAGCc----------------------------------------------- 20 0,-1 ---------AGGGCUUAGCUGCUUGUGAGCA----------------------------------------------- 2758 0,0 ---------AGGGCUUAGCUGCUUGUGAGCAa---------------------------------------------- 2 0,0 ----------GGGCUUAGCUGCUUGUGAGC------------------------------------------------ 8 1,-1 ----------GGGCUUAGCUGCUUGUGAGCA----------------------------------------------- 83 1,0 -------------------------------------------------GUUCACAGUGGCUAAGUU----------- 3 -1,-4 -------------------------------------------------GUUCACAGUGGCUAAGUUC---------- 14 -1,-3 -------------------------------------------------GUUCACAGUGGCUAAGUUCCG-------- 9 -1,-1 -------------------------------------------------GUUCACAGUGGCUAAGUUCCGC------- 4 -1,0 --------------------------------------------------UUCACAGUGGCUAAGUUC---------- 7172 0,-3 --------------------------------------------------UUCACAGUGGCUAAGUUCa--------- 684 0,-3 --------------------------------------------------UUCACAGUGGCUAAGUUCaa-------- 46 0,-3 --------------------------------------------------UUCACAGUGGCUAAGUUCau-------- 2 0,-3 --------------------------------------------------UUCACAGUGGCUAAGUUCg--------- 23 0,-3 --------------------------------------------------UUCACAGUGGCUAAGUUCC--------- 9652 0,-2 --------------------------------------------------UUCACAGUGGCUAAGUUCCa-------- 519 0,-2 --------------------------------------------------UUCACAGUGGCUAAGUUCCaa------- 45 0,-2 --------------------------------------------------UUCACAGUGGCUAAGUUCCau------- 46 0,-2 --------------------------------------------------UUCACAGUGGCUAAGUUCCc-------- 60 0,-2 --------------------------------------------------UUCACAGUGGCUAAGUUCCu-------- 485 0,-2 --------------------------------------------------UUCACAGUGGCUAAGUUCCuu------- 632 0,-2 --------------------------------------------------UUCACAGUGGCUAAGUUCCG-------- 122147 0,-1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGa------- 12088 0,-1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGaa------ 1524 0,-1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGau------ 879 0,-1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGg------- 263 0,-1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGu------- 21226 0,-1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGuu------ 9885 0,-1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGC------- 95015 0,0 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCa------ 17362 0,0 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCaa----- 3133 0,0 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCau----- 3240 0,0 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCg------ 353 0,0 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCu------ 41755 0,0 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCuu----- 2225 0,0 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCC------ 849 0,1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCCa----- 115 0,1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCCaa---- 2 0,1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCCau---- 2 0,1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCCg----- 7 0,1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCCu----- 154 0,1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCCuu---- 6 0,1 --------------------------------------------------UUCACAGUGGCUAAGUUCCGCCC----- 2 0,2 ---------------------------------------------------UCACAGUGGCUAAGUUCC--------- 104 1,-2 ---------------------------------------------------UCACAGUGGCUAAGUUCCa-------- 4 1,-2 ---------------------------------------------------UCACAGUGGCUAAGUUCCuu------- 7 1,-2 ---------------------------------------------------UCACAGUGGCUAAGUUCCG-------- 1619 1,-1 ---------------------------------------------------UCACAGUGGCUAAGUUCCGa------- 238 1,-1 ---------------------------------------------------UCACAGUGGCUAAGUUCCGaa------ 4 1,-1 ---------------------------------------------------UCACAGUGGCUAAGUUCCGau------ 14 1,-1 ---------------------------------------------------UCACAGUGGCUAAGUUCCGu------- 356 1,-1 ---------------------------------------------------UCACAGUGGCUAAGUUCCGuu------ 175 1,-1 ---------------------------------------------------UCACAGUGGCUAAGUUCCGC------- 1702 1,0 ---------------------------------------------------UCACAGUGGCUAAGUUCCGCa------ 266 1,0 ---------------------------------------------------UCACAGUGGCUAAGUUCCGCaa----- 41 1,0 ---------------------------------------------------UCACAGUGGCUAAGUUCCGCau----- 51 1,0 ---------------------------------------------------UCACAGUGGCUAAGUUCCGCg------ 2 1,0 ---------------------------------------------------UCACAGUGGCUAAGUUCCGCu------ 724 1,0 ---------------------------------------------------UCACAGUGGCUAAGUUCCGCuu----- 28 1,0 ---------------------------------------------------UCACAGUGGCUAAGUUCCGCC------ 21 1,1 ----------------------------------------------------CACAGUGGCUAAGUUCCG-------- 102 2,-1 ----------------------------------------------------CACAGUGGCUAAGUUCCGu------- 13 2,-1 ----------------------------------------------------CACAGUGGCUAAGUUCCGuu------ 7 2,-1 ----------------------------------------------------CACAGUGGCUAAGUUCCGC------- 69 2,0 ----------------------------------------------------CACAGUGGCUAAGUUCCGCa------ 22 2,0 ----------------------------------------------------CACAGUGGCUAAGUUCCGCu------ 43 2,0 >hsa-mir-27b mi:19-40;MA:61-81 Tumor accucucuaacaaggugcAGAGCUUAGCUGAUUGGUGAACagugauugguuuccgcuuugUUCACAGUGGCUAAGUUCUGCaccugaagagaaggug -----------------CAGAGCUUAGCUGAUUGGUGA----------------------------------------------------------- 2 -1,-2 -----------------CAGAGCUUAGCUGAUUGGUGAA---------------------------------------------------------- 4 -1,-1 -----------------CAGAGCUUAGCUGAUUGGUGAAa--------------------------------------------------------- 2 -1,-1 -----------------CAGAGCUUAGCUGAUUGGUGAAC--------------------------------------------------------- 7 -1,0 -----------------CAGAGCUUAGCUGAUUGGUGAACA-------------------------------------------------------- 13 -1,1 ------------------AGAGCUUAGCUGAUUGGUG------------------------------------------------------------ 4 0,-3 ------------------AGAGCUUAGCUGAUUGGUGA----------------------------------------------------------- 34 0,-2 ------------------AGAGCUUAGCUGAUUGGUGAA---------------------------------------------------------- 56 0,-1 ------------------AGAGCUUAGCUGAUUGGUGAAa--------------------------------------------------------- 8 0,-1 ------------------AGAGCUUAGCUGAUUGGUGAAaa-------------------------------------------------------- 2 0,-1 ------------------AGAGCUUAGCUGAUUGGUGAAC--------------------------------------------------------- 573 0,0 ------------------AGAGCUUAGCUGAUUGGUGAACu-------------------------------------------------------- 3 0,0 ------------------AGAGCUUAGCUGAUUGGUGAACA-------------------------------------------------------- 502 0,1 ------------------AGAGCUUAGCUGAUUGGUGAACAG------------------------------------------------------- 24 0,2 ------------------AGAGCUUAGCUGAUUGGUGAACAGU------------------------------------------------------ 17 0,3 -------------------GAGCUUAGCUGAUUGGUGAACA-------------------------------------------------------- 2 1,1 -----------------------------------------------------------GUUCACAGUGGCUAAGUU-------------------- 3 -1,-4 -----------------------------------------------------------GUUCACAGUGGCUAAGUUC------------------- 14 -1,-3 -----------------------------------------------------------GUUCACAGUGGCUAAGUUCU------------------ 100 -1,-2 -----------------------------------------------------------GUUCACAGUGGCUAAGUUCUG----------------- 167 -1,-1 -----------------------------------------------------------GUUCACAGUGGCUAAGUUCUGa---------------- 53 -1,-1 -----------------------------------------------------------GUUCACAGUGGCUAAGUUCUGaa--------------- 6 -1,-1 -----------------------------------------------------------GUUCACAGUGGCUAAGUUCUGu---------------- 48 -1,-1 -----------------------------------------------------------GUUCACAGUGGCUAAGUUCUGC---------------- 489 -1,0 -----------------------------------------------------------GUUCACAGUGGCUAAGUUCUGCu--------------- 17 -1,0 -----------------------------------------------------------GUUCACAGUGGCUAAGUUCUGCA--------------- 67 -1,1 -----------------------------------------------------------GUUCACAGUGGCUAAGUUCUGCAa-------------- 2 -1,1 -----------------------------------------------------------GUUCACAGUGGCUAAGUUCUGCAu-------------- 2 -1,1 ------------------------------------------------------------UUCACAGUGGCUAAGUUC------------------- 7172 0,-3 ------------------------------------------------------------UUCACAGUGGCUAAGUUCa------------------ 684 0,-3 ------------------------------------------------------------UUCACAGUGGCUAAGUUCaa----------------- 46 0,-3 ------------------------------------------------------------UUCACAGUGGCUAAGUUCau----------------- 2 0,-3 ------------------------------------------------------------UUCACAGUGGCUAAGUUCg------------------ 23 0,-3 ------------------------------------------------------------UUCACAGUGGCUAAGUUCU------------------ 8364 0,-2 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUa----------------- 84 0,-2 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUaa---------------- 29 0,-2 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUau---------------- 11 0,-2 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUc----------------- 4 0,-2 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUu----------------- 246 0,-2 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUuu---------------- 235 0,-2 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUG----------------- 20759 0,-1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGa---------------- 5492 0,-1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGaa--------------- 671 0,-1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGau--------------- 88 0,-1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGg---------------- 48 0,-1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGu---------------- 6728 0,-1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGuu--------------- 354 0,-1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGC---------------- 63651 0,0 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCc--------------- 457 0,0 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCg--------------- 133 0,0 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCu--------------- 11481 0,0 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCuu-------------- 899 0,0 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCA--------------- 12324 0,1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCAa-------------- 2712 0,1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCAaa------------- 43 0,1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCAau------------- 55 0,1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCAg-------------- 205 0,1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCAu-------------- 2094 0,1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCAuu------------- 47 0,1 ------------------------------------------------------------UUCACAGUGGCUAAGUUCUGCAC-------------- 15 0,2 -------------------------------------------------------------UCACAGUGGCUAAGUUCU------------------ 122 1,-2 -------------------------------------------------------------UCACAGUGGCUAAGUUCUG----------------- 265 1,-1 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGa---------------- 88 1,-1 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGaa--------------- 2 1,-1 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGu---------------- 107 1,-1 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGuu--------------- 2 1,-1 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGC---------------- 1125 1,0 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGCc--------------- 2 1,0 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGCu--------------- 280 1,0 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGCuu-------------- 76 1,0 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGCA--------------- 188 1,1 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGCAa-------------- 34 1,1 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGCAg-------------- 2 1,1 -------------------------------------------------------------UCACAGUGGCUAAGUUCUGCAu-------------- 40 1,1 --------------------------------------------------------------CACAGUGGCUAAGUUCUG----------------- 6 2,-1 --------------------------------------------------------------CACAGUGGCUAAGUUCUGa---------------- 4 2,-1 --------------------------------------------------------------CACAGUGGCUAAGUUCUGu---------------- 3 2,-1 --------------------------------------------------------------CACAGUGGCUAAGUUCUGC---------------- 55 2,0 --------------------------------------------------------------CACAGUGGCUAAGUUCUGCu--------------- 8 2,0 --------------------------------------------------------------CACAGUGGCUAAGUUCUGCA--------------- 12 2,1 --------------------------------------------------------------CACAGUGGCUAAGUUCUGCAu-------------- 3 2,1 >hsa-mir-28 5p:14-35;3p:54-75 Tumor gguccuugcccucAAGGAGCUCACAGUCUAUUGAGuuaccuuucugacuuuccCACUAGAUUGUGAGCUCCUGGAgggcaggcacu -----------UCAAGGAGCUCACAGUCUA-------------------------------------------------------- 57 -2,-5 -----------UCAAGGAGCUCACAGUCUAg------------------------------------------------------- 4 -2,-5 ------------CAAGGAGCUCACAGUCUAUU------------------------------------------------------ 9 -1,-3 ------------CAAGGAGCUCACAGUCUAUUG----------------------------------------------------- 67 -1,-2 ------------CAAGGAGCUCACAGUCUAUUGu---------------------------------------------------- 2 -1,-2 ------------CAAGGAGCUCACAGUCUAUUGA---------------------------------------------------- 180 -1,-1 ------------CAAGGAGCUCACAGUCUAUUGAG--------------------------------------------------- 26 -1,0 -------------AAGGAGCUCACAGUCUAU------------------------------------------------------- 72 0,-4 -------------AAGGAGCUCACAGUCUAUa------------------------------------------------------ 2 0,-4 -------------AAGGAGCUCACAGUCUAUaa----------------------------------------------------- 3 0,-4 -------------AAGGAGCUCACAGUCUAUU------------------------------------------------------ 874 0,-3 -------------AAGGAGCUCACAGUCUAUUa----------------------------------------------------- 47 0,-3 -------------AAGGAGCUCACAGUCUAUUaa---------------------------------------------------- 62 0,-3 -------------AAGGAGCUCACAGUCUAUUau---------------------------------------------------- 3 0,-3 -------------AAGGAGCUCACAGUCUAUUu----------------------------------------------------- 16 0,-3 -------------AAGGAGCUCACAGUCUAUUG----------------------------------------------------- 1906 0,-2 -------------AAGGAGCUCACAGUCUAUUGc---------------------------------------------------- 4 0,-2 -------------AAGGAGCUCACAGUCUAUUGg---------------------------------------------------- 4 0,-2 -------------AAGGAGCUCACAGUCUAUUGu---------------------------------------------------- 160 0,-2 -------------AAGGAGCUCACAGUCUAUUGA---------------------------------------------------- 10160 0,-1 -------------AAGGAGCUCACAGUCUAUUGAa--------------------------------------------------- 1097 0,-1 -------------AAGGAGCUCACAGUCUAUUGAaa-------------------------------------------------- 206 0,-1 -------------AAGGAGCUCACAGUCUAUUGAau-------------------------------------------------- 8 0,-1 -------------AAGGAGCUCACAGUCUAUUGAc--------------------------------------------------- 10 0,-1 -------------AAGGAGCUCACAGUCUAUUGAu--------------------------------------------------- 76 0,-1 -------------AAGGAGCUCACAGUCUAUUGAG--------------------------------------------------- 8303 0,0 -------------AAGGAGCUCACAGUCUAUUGAGa-------------------------------------------------- 2397 0,0 -------------AAGGAGCUCACAGUCUAUUGAGaa------------------------------------------------- 20 0,0 -------------AAGGAGCUCACAGUCUAUUGAGau------------------------------------------------- 2 0,0 -------------AAGGAGCUCACAGUCUAUUGAGc-------------------------------------------------- 2 0,0 -------------AAGGAGCUCACAGUCUAUUGAGg-------------------------------------------------- 6 0,0 -------------AAGGAGCUCACAGUCUAUUGAGU-------------------------------------------------- 881 0,1 -------------AAGGAGCUCACAGUCUAUUGAGUa------------------------------------------------- 2 0,1 -------------AAGGAGCUCACAGUCUAUUGAGUU------------------------------------------------- 11 0,2 --------------AGGAGCUCACAGUCUAUU------------------------------------------------------ 7 1,-3 --------------AGGAGCUCACAGUCUAUUG----------------------------------------------------- 30 1,-2 --------------AGGAGCUCACAGUCUAUUGA---------------------------------------------------- 161 1,-1 --------------AGGAGCUCACAGUCUAUUGAa--------------------------------------------------- 7 1,-1 --------------AGGAGCUCACAGUCUAUUGAu--------------------------------------------------- 2 1,-1 --------------AGGAGCUCACAGUCUAUUGAG--------------------------------------------------- 185 1,0 --------------AGGAGCUCACAGUCUAUUGAGa-------------------------------------------------- 44 1,0 --------------AGGAGCUCACAGUCUAUUGAGU-------------------------------------------------- 12 1,1 ----------------------------------------------------CCACUAGAUUGUGAGCUCCUGG------------ 4 -1,-1 ----------------------------------------------------CCACUAGAUUGUGAGCUCCUGGA----------- 4 -1,0 -----------------------------------------------------CACUAGAUUGUGAGCUCC--------------- 4 0,-4 -----------------------------------------------------CACUAGAUUGUGAGCUCCU-------------- 49 0,-3 -----------------------------------------------------CACUAGAUUGUGAGCUCCUu------------- 2 0,-3 -----------------------------------------------------CACUAGAUUGUGAGCUCCUG------------- 87 0,-2 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGa------------ 44 0,-2 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGaa----------- 20 0,-2 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGu------------ 42 0,-2 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGG------------ 1784 0,-1 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGc----------- 27 0,-1 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGg----------- 2 0,-1 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGu----------- 186 0,-1 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGuu---------- 6 0,-1 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGA----------- 8902 0,0 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAa---------- 2965 0,0 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAaa--------- 362 0,0 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAau--------- 217 0,0 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAc---------- 13 0,0 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAu---------- 1694 0,0 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAuu--------- 56 0,0 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAG---------- 630 0,1 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAGa--------- 71 0,1 -----------------------------------------------------CACUAGAUUGUGAGCUCCUGGAGu--------- 103 0,1 ------------------------------------------------------ACUAGAUUGUGAGCUCCUG------------- 2 1,-2 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGG------------ 60 1,-1 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGu----------- 2 1,-1 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGA----------- 464 1,0 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGAa---------- 151 1,0 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGAaa--------- 8 1,0 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGAau--------- 8 1,0 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGAu---------- 66 1,0 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGAG---------- 781 1,1 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGAGa--------- 165 1,1 ------------------------------------------------------ACUAGAUUGUGAGCUCCUGGAGu--------- 162 1,1 -------------------------------------------------------CUAGAUUGUGAGCUCCUGGA----------- 10 2,0 -------------------------------------------------------CUAGAUUGUGAGCUCCUGGAa---------- 4 2,0 -------------------------------------------------------CUAGAUUGUGAGCUCCUGGAu---------- 2 2,0 -------------------------------------------------------CUAGAUUGUGAGCUCCUGGAG---------- 208 2,1 -------------------------------------------------------CUAGAUUGUGAGCUCCUGGAGa--------- 35 2,1 -------------------------------------------------------CUAGAUUGUGAGCUCCUGGAGu--------- 108 2,1 >hsa-mir-296 5p:14-34;3p:48-69 Tumor aggacccuuccagAGGGCCCCCCCUCAAUCCUGUugugccuaauucaGAGGGUUGGGUGGAGGCUCUCCugaagggcucu ------------GAGGGCCCCCCCUCAAUCCUGc---------------------------------------------- 2 -1,-1 ------------GAGGGCCCCCCCUCAAUCCUGU---------------------------------------------- 17 -1,0 -------------AGGGCCCCCCCUCAAUCCUGU---------------------------------------------- 178 0,0 -------------AGGGCCCCCCCUCAAUCCUGUa--------------------------------------------- 2 0,0 -------------AGGGCCCCCCCUCAAUCCUGUU--------------------------------------------- 2 0,1 --------------GGGCCCCCCCUCAAUCCUGU---------------------------------------------- 2 1,0 -----------------------------------------------GAGGGUUGGGUGGAGGCU--------------- 2 0,-4 -----------------------------------------------GAGGGUUGGGUGGAGGCUC-------------- 3 0,-3 -----------------------------------------------GAGGGUUGGGUGGAGGCUCa------------- 2 0,-3 -----------------------------------------------GAGGGUUGGGUGGAGGCUCU------------- 24 0,-2 -----------------------------------------------GAGGGUUGGGUGGAGGCUCUu------------ 2 0,-2 -----------------------------------------------GAGGGUUGGGUGGAGGCUCUC------------ 6 0,-1 -----------------------------------------------GAGGGUUGGGUGGAGGCUCUCC----------- 16 0,0 -----------------------------------------------GAGGGUUGGGUGGAGGCUCUCCa---------- 2 0,0 ------------------------------------------------AGGGUUGGGUGGAGGCUCU------------- 43 1,-2 ------------------------------------------------AGGGUUGGGUGGAGGCUCUC------------ 5 1,-1 ------------------------------------------------AGGGUUGGGUGGAGGCUCUCC----------- 9 1,0 ------------------------------------------------AGGGUUGGGUGGAGGCUCUCCc---------- 2 1,0 ------------------------------------------------AGGGUUGGGUGGAGGCUCUCCU---------- 6 1,1 >hsa-mir-2964a 5p:14-35;3p:56-78 Tumor ggagcucagccacAGAUGUCCAGCCACAAUUCUCGguuggccgcagacucguacaAGAAUUGCGUUUGGACAAUCAGUggcgaagccc -------------AGAUGUCCAGCCACAAUUCUCG----------------------------------------------------- 6 0,0 -------------AGAUGUCCAGCCACAAUUCUCGa---------------------------------------------------- 2 0,0 -------------------------------------------------------AGAAUUGCGUUUGGACAAUCAGU---------- 2 0,0 >hsa-mir-299 5p:7-28;3p:39-60 Tumor aagaaaUGGUUUACCGUCCCACAUACAUuuugaauaugUAUGUGGGAUGGUAAACCGCUUcuu -----AUGGUUUACCGUCCCACAUAC------------------------------------- 28 -1,-2 -----AUGGUUUACCGUCCCACAUACA------------------------------------ 113 -1,-1 ------UGGUUUACCGUCCCACAUA-------------------------------------- 2 0,-3 ------UGGUUUACCGUCCCACAUAC------------------------------------- 59 0,-2 ------UGGUUUACCGUCCCACAUACA------------------------------------ 176 0,-1 ------UGGUUUACCGUCCCACAUACAa----------------------------------- 2 0,-1 ------UGGUUUACCGUCCCACAUACAc----------------------------------- 5 0,-1 ------UGGUUUACCGUCCCACAUACAU----------------------------------- 264 0,0 ------UGGUUUACCGUCCCACAUACAUU---------------------------------- 2 0,1 -------------------------------------GUAUGUGGGAUGGUAAACCGCU---- 22 -1,-1 --------------------------------------UAUGUGGGAUGGUAAACCGC----- 2 0,-2 --------------------------------------UAUGUGGGAUGGUAAACCGCU---- 76 0,-1 --------------------------------------UAUGUGGGAUGGUAAACCGCUU--- 84 0,0 --------------------------------------UAUGUGGGAUGGUAAACCGCUUa-- 16 0,0 --------------------------------------UAUGUGGGAUGGUAAACCGCUUaa- 2 0,0 --------------------------------------UAUGUGGGAUGGUAAACCGCUUu-- 9 0,0 ---------------------------------------AUGUGGGAUGGUAAACCGCUU--- 2 1,0 ---------------------------------------AUGUGGGAUGGUAAACCGCUUa-- 3 1,0 >hsa-mir-29a mi:4-25;MA:42-63 Tumor augACUGAUUUCUUUUGGUGUUCAGagucaauauaauuuucUAGCACCAUCUGAAAUCGGUUAu ---ACUGAUUUCUUUUGGUGUU------------------------------------------ 29 0,-3 ---ACUGAUUUCUUUUGGUGUUa----------------------------------------- 11 0,-3 ---ACUGAUUUCUUUUGGUGUUaa---------------------------------------- 2 0,-3 ---ACUGAUUUCUUUUGGUGUUC----------------------------------------- 112 0,-2 ---ACUGAUUUCUUUUGGUGUUCc---------------------------------------- 2 0,-2 ---ACUGAUUUCUUUUGGUGUUCA---------------------------------------- 315 0,-1 ---ACUGAUUUCUUUUGGUGUUCAa--------------------------------------- 11 0,-1 ---ACUGAUUUCUUUUGGUGUUCAu--------------------------------------- 8 0,-1 ---ACUGAUUUCUUUUGGUGUUCAG--------------------------------------- 445 0,0 ---ACUGAUUUCUUUUGGUGUUCAGc-------------------------------------- 2 0,0 ---ACUGAUUUCUUUUGGUGUUCAGu-------------------------------------- 23 0,0 ---ACUGAUUUCUUUUGGUGUUCAGA-------------------------------------- 1162 0,1 ---ACUGAUUUCUUUUGGUGUUCAGAa------------------------------------- 10 0,1 ---ACUGAUUUCUUUUGGUGUUCAGAG------------------------------------- 153 0,2 ---ACUGAUUUCUUUUGGUGUUCAGAGU------------------------------------ 56 0,3 ----CUGAUUUCUUUUGGUGUUCA---------------------------------------- 2 1,-1 ----CUGAUUUCUUUUGGUGUUCAGA-------------------------------------- 8 1,1 -----UGAUUUCUUUUGGUGUUCAG--------------------------------------- 2 2,0 -----UGAUUUCUUUUGGUGUUCAGA-------------------------------------- 2 2,1 -----UGAUUUCUUUUGGUGUUCAGAG------------------------------------- 2 2,2 ---------------------------------------UCUAGCACCAUCUGAAAUCGGU--- 5 -2,-2 ---------------------------------------UCUAGCACCAUCUGAAAUCGGUU-- 45 -2,-1 ---------------------------------------UCUAGCACCAUCUGAAAUCGGUUA- 30 -2,0 ---------------------------------------UCUAGCACCAUCUGAAAUCGGUUAa 2 -2,0 ----------------------------------------CUAGCACCAUCUGAAAUC------ 39 -1,-5 ----------------------------------------CUAGCACCAUCUGAAAUCG----- 324 -1,-4 ----------------------------------------CUAGCACCAUCUGAAAUCGa---- 2 -1,-4 ----------------------------------------CUAGCACCAUCUGAAAUCGau--- 4 -1,-4 ----------------------------------------CUAGCACCAUCUGAAAUCGuu--- 8 -1,-4 ----------------------------------------CUAGCACCAUCUGAAAUCGG---- 479 -1,-3 ----------------------------------------CUAGCACCAUCUGAAAUCGGa--- 23 -1,-3 ----------------------------------------CUAGCACCAUCUGAAAUCGGaa-- 2 -1,-3 ----------------------------------------CUAGCACCAUCUGAAAUCGGau-- 8 -1,-3 ----------------------------------------CUAGCACCAUCUGAAAUCGGc--- 4 -1,-3 ----------------------------------------CUAGCACCAUCUGAAAUCGGg--- 6 -1,-3 ----------------------------------------CUAGCACCAUCUGAAAUCGGU--- 3784 -1,-2 ----------------------------------------CUAGCACCAUCUGAAAUCGGUa-- 567 -1,-2 ----------------------------------------CUAGCACCAUCUGAAAUCGGUaa- 99 -1,-2 ----------------------------------------CUAGCACCAUCUGAAAUCGGUau- 2 -1,-2 ----------------------------------------CUAGCACCAUCUGAAAUCGGUc-- 12 -1,-2 ----------------------------------------CUAGCACCAUCUGAAAUCGGUg-- 8 -1,-2 ----------------------------------------CUAGCACCAUCUGAAAUCGGUU-- 18566 -1,-1 ----------------------------------------CUAGCACCAUCUGAAAUCGGUUc- 4 -1,-1 ----------------------------------------CUAGCACCAUCUGAAAUCGGUUg- 18 -1,-1 ----------------------------------------CUAGCACCAUCUGAAAUCGGUUu- 1022 -1,-1 ----------------------------------------CUAGCACCAUCUGAAAUCGGUUuu 4 -1,-1 ----------------------------------------CUAGCACCAUCUGAAAUCGGUUA- 4258 -1,0 ----------------------------------------CUAGCACCAUCUGAAAUCGGUUAa 282 -1,0 ----------------------------------------CUAGCACCAUCUGAAAUCGGUUAg 4 -1,0 ----------------------------------------CUAGCACCAUCUGAAAUCGGUUAU 139 -1,1 -----------------------------------------UAGCACCAUCUGAAAUCG----- 1392 0,-4 -----------------------------------------UAGCACCAUCUGAAAUCGa---- 98 0,-4 -----------------------------------------UAGCACCAUCUGAAAUCGau--- 44 0,-4 -----------------------------------------UAGCACCAUCUGAAAUCGu---- 8 0,-4 -----------------------------------------UAGCACCAUCUGAAAUCGuu--- 81 0,-4 -----------------------------------------UAGCACCAUCUGAAAUCGG---- 3997 0,-3 -----------------------------------------UAGCACCAUCUGAAAUCGGa--- 366 0,-3 -----------------------------------------UAGCACCAUCUGAAAUCGGaa-- 105 0,-3 -----------------------------------------UAGCACCAUCUGAAAUCGGau-- 78 0,-3 -----------------------------------------UAGCACCAUCUGAAAUCGGc--- 40 0,-3 -----------------------------------------UAGCACCAUCUGAAAUCGGg--- 19 0,-3 -----------------------------------------UAGCACCAUCUGAAAUCGGU--- 28788 0,-2 -----------------------------------------UAGCACCAUCUGAAAUCGGUa-- 3907 0,-2 -----------------------------------------UAGCACCAUCUGAAAUCGGUaa- 3044 0,-2 -----------------------------------------UAGCACCAUCUGAAAUCGGUau- 273 0,-2 -----------------------------------------UAGCACCAUCUGAAAUCGGUc-- 173 0,-2 -----------------------------------------UAGCACCAUCUGAAAUCGGUg-- 63 0,-2 -----------------------------------------UAGCACCAUCUGAAAUCGGUU-- 127994 0,-1 -----------------------------------------UAGCACCAUCUGAAAUCGGUUc- 655 0,-1 -----------------------------------------UAGCACCAUCUGAAAUCGGUUg- 493 0,-1 -----------------------------------------UAGCACCAUCUGAAAUCGGUUu- 6650 0,-1 -----------------------------------------UAGCACCAUCUGAAAUCGGUUuu 237 0,-1 -----------------------------------------UAGCACCAUCUGAAAUCGGUUA- 121993 0,0 -----------------------------------------UAGCACCAUCUGAAAUCGGUUAa 23162 0,0 -----------------------------------------UAGCACCAUCUGAAAUCGGUUAaa 502 0,0 -----------------------------------------UAGCACCAUCUGAAAUCGGUUAau 71 0,0 -----------------------------------------UAGCACCAUCUGAAAUCGGUUAc 152 0,0 -----------------------------------------UAGCACCAUCUGAAAUCGGUUAg 539 0,0 -----------------------------------------UAGCACCAUCUGAAAUCGGUUAU 7701 0,1 -----------------------------------------UAGCACCAUCUGAAAUCGGUUAUa 7 0,1 -----------------------------------------UAGCACCAUCUGAAAUCGGUUAUu 61 0,1 ------------------------------------------AGCACCAUCUGAAAUCGG---- 135 1,-3 ------------------------------------------AGCACCAUCUGAAAUCGGau-- 8 1,-3 ------------------------------------------AGCACCAUCUGAAAUCGGU--- 1192 1,-2 ------------------------------------------AGCACCAUCUGAAAUCGGUa-- 134 1,-2 ------------------------------------------AGCACCAUCUGAAAUCGGUaa- 114 1,-2 ------------------------------------------AGCACCAUCUGAAAUCGGUau- 6 1,-2 ------------------------------------------AGCACCAUCUGAAAUCGGUc-- 12 1,-2 ------------------------------------------AGCACCAUCUGAAAUCGGUU-- 6105 1,-1 ------------------------------------------AGCACCAUCUGAAAUCGGUUc- 4 1,-1 ------------------------------------------AGCACCAUCUGAAAUCGGUUg- 10 1,-1 ------------------------------------------AGCACCAUCUGAAAUCGGUUu- 287 1,-1 ------------------------------------------AGCACCAUCUGAAAUCGGUUuu 2 1,-1 ------------------------------------------AGCACCAUCUGAAAUCGGUUA- 5710 1,0 ------------------------------------------AGCACCAUCUGAAAUCGGUUAa 1051 1,0 ------------------------------------------AGCACCAUCUGAAAUCGGUUAaa 10 1,0 ------------------------------------------AGCACCAUCUGAAAUCGGUUAg 9 1,0 ------------------------------------------AGCACCAUCUGAAAUCGGUUAU 341 1,1 -------------------------------------------GCACCAUCUGAAAUCGGU--- 40 2,-2 -------------------------------------------GCACCAUCUGAAAUCGGUU-- 268 2,-1 -------------------------------------------GCACCAUCUGAAAUCGGUUu- 6 2,-1 -------------------------------------------GCACCAUCUGAAAUCGGUUA- 287 2,0 -------------------------------------------GCACCAUCUGAAAUCGGUUAa 41 2,0 -------------------------------------------GCACCAUCUGAAAUCGGUUAU 7 2,1 >hsa-mir-29b-1 mi:10-33;MA:51-73 Tumor cuucaggaaGCUGGUUUCAUAUGGUGGUUUAGAuuuaaauagugauugucUAGCACCAUUUGAAAUCAGUGUUcuuggggg ---------GCUGGUUUCAUAUGGUGGUUU--------------------------------------------------- 15 0,-3 ---------GCUGGUUUCAUAUGGUGGUUUA-------------------------------------------------- 7 0,-2 ---------GCUGGUUUCAUAUGGUGGUUUAG------------------------------------------------- 9 0,-1 ---------GCUGGUUUCAUAUGGUGGUUUAGA------------------------------------------------ 68 0,0 -------------------------------------------------CUAGCACCAUUUGAAAUCA------------- 90 -1,-5 -------------------------------------------------CUAGCACCAUUUGAAAUCAuu----------- 2 -1,-5 -------------------------------------------------CUAGCACCAUUUGAAAUCAG------------ 233 -1,-4 -------------------------------------------------CUAGCACCAUUUGAAAUCAGa----------- 4 -1,-4 -------------------------------------------------CUAGCACCAUUUGAAAUCAGg----------- 2 -1,-4 -------------------------------------------------CUAGCACCAUUUGAAAUCAGU----------- 2444 -1,-3 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUa---------- 42 -1,-3 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUaa--------- 2 -1,-3 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUau--------- 4 -1,-3 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUc---------- 4 -1,-3 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUu---------- 243 -1,-3 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUuu--------- 26 -1,-3 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUG---------- 4861 -1,-2 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUGa--------- 991 -1,-2 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUGaa-------- 6 -1,-2 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUGau-------- 4 -1,-2 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUGc--------- 2 -1,-2 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUGg--------- 8 -1,-2 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUGU--------- 6034 -1,-1 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUGUa-------- 14 -1,-1 -------------------------------------------------CUAGCACCAUUUGAAAUCAGUGUU-------- 287 -1,0 --------------------------------------------------UAGCACCAUUUGAAAUCA------------- 526 0,-5 --------------------------------------------------UAGCACCAUUUGAAAUCAa------------ 2 0,-5 --------------------------------------------------UAGCACCAUUUGAAAUCAau----------- 5 0,-5 --------------------------------------------------UAGCACCAUUUGAAAUCAuu----------- 2 0,-5 --------------------------------------------------UAGCACCAUUUGAAAUCAG------------ 1210 0,-4 --------------------------------------------------UAGCACCAUUUGAAAUCAGa----------- 90 0,-4 --------------------------------------------------UAGCACCAUUUGAAAUCAGc----------- 7 0,-4 --------------------------------------------------UAGCACCAUUUGAAAUCAGU----------- 6254 0,-3 --------------------------------------------------UAGCACCAUUUGAAAUCAGUa---------- 93 0,-3 --------------------------------------------------UAGCACCAUUUGAAAUCAGUaa--------- 34 0,-3 --------------------------------------------------UAGCACCAUUUGAAAUCAGUau--------- 51 0,-3 --------------------------------------------------UAGCACCAUUUGAAAUCAGUc---------- 4 0,-3 --------------------------------------------------UAGCACCAUUUGAAAUCAGUu---------- 334 0,-3 --------------------------------------------------UAGCACCAUUUGAAAUCAGUuu--------- 197 0,-3 --------------------------------------------------UAGCACCAUUUGAAAUCAGUG---------- 13292 0,-2 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGa--------- 5560 0,-2 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGaa-------- 326 0,-2 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGau-------- 89 0,-2 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGc--------- 82 0,-2 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGg--------- 57 0,-2 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGU--------- 35342 0,-1 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGUa-------- 1422 0,-1 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGUaa------- 93 0,-1 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGUau------- 9 0,-1 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGUc-------- 129 0,-1 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGUg-------- 11 0,-1 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGUU-------- 99937 0,0 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGUUa------- 368 0,0 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGUUaa------ 2 0,0 --------------------------------------------------UAGCACCAUUUGAAAUCAGUGUUg------- 311 0,0 ---------------------------------------------------AGCACCAUUUGAAAUCAG------------ 27 1,-4 ---------------------------------------------------AGCACCAUUUGAAAUCAGU----------- 193 1,-3 ---------------------------------------------------AGCACCAUUUGAAAUCAGUu---------- 2 1,-3 ---------------------------------------------------AGCACCAUUUGAAAUCAGUuu--------- 4 1,-3 ---------------------------------------------------AGCACCAUUUGAAAUCAGUG---------- 563 1,-2 ---------------------------------------------------AGCACCAUUUGAAAUCAGUGa--------- 228 1,-2 ---------------------------------------------------AGCACCAUUUGAAAUCAGUGaa-------- 9 1,-2 ---------------------------------------------------AGCACCAUUUGAAAUCAGUGg--------- 2 1,-2 ---------------------------------------------------AGCACCAUUUGAAAUCAGUGU--------- 1575 1,-1 ---------------------------------------------------AGCACCAUUUGAAAUCAGUGUa-------- 38 1,-1 ---------------------------------------------------AGCACCAUUUGAAAUCAGUGUU-------- 4439 1,0 ---------------------------------------------------AGCACCAUUUGAAAUCAGUGUUa------- 10 1,0 ---------------------------------------------------AGCACCAUUUGAAAUCAGUGUUg------- 2 1,0 ----------------------------------------------------GCACCAUUUGAAAUCAGUG---------- 10 2,-2 ----------------------------------------------------GCACCAUUUGAAAUCAGUGa--------- 2 2,-2 ----------------------------------------------------GCACCAUUUGAAAUCAGUGU--------- 58 2,-1 ----------------------------------------------------GCACCAUUUGAAAUCAGUGUU-------- 207 2,0 >hsa-mir-29b-2 mi:11-32;MA:52-74 Tumor cuucuggaagCUGGUUUCACAUGGUGGCUUAGauuuuuccaucuuuguaucUAGCACCAUUUGAAAUCAGUGUUuuaggag ---------GCUGGUUUCACAUGGUGGCU---------------------------------------------------- 8 -1,-3 ---------GCUGGUUUCACAUGGUGGCUU--------------------------------------------------- 4 -1,-2 ---------GCUGGUUUCACAUGGUGGCUUAG------------------------------------------------- 8 -1,0 ---------GCUGGUUUCACAUGGUGGCUUAGA------------------------------------------------ 116 -1,1 ----------CUGGUUUCACAUGGUGGCUU--------------------------------------------------- 17 0,-2 ----------CUGGUUUCACAUGGUGGCUUu-------------------------------------------------- 5 0,-2 ----------CUGGUUUCACAUGGUGGCUUA-------------------------------------------------- 20 0,-1 ----------CUGGUUUCACAUGGUGGCUUAa------------------------------------------------- 2 0,-1 ----------CUGGUUUCACAUGGUGGCUUAG------------------------------------------------- 172 0,0 ----------CUGGUUUCACAUGGUGGCUUAGc------------------------------------------------ 2 0,0 ----------CUGGUUUCACAUGGUGGCUUAGu------------------------------------------------ 38 0,0 ----------CUGGUUUCACAUGGUGGCUUAGA------------------------------------------------ 1166 0,1 ----------CUGGUUUCACAUGGUGGCUUAGAa----------------------------------------------- 8 0,1 ----------CUGGUUUCACAUGGUGGCUUAGAU----------------------------------------------- 489 0,2 ----------CUGGUUUCACAUGGUGGCUUAGAUa---------------------------------------------- 2 0,2 ----------CUGGUUUCACAUGGUGGCUUAGAUU---------------------------------------------- 14 0,3 -----------UGGUUUCACAUGGUGGCUUAG------------------------------------------------- 12 1,0 -----------UGGUUUCACAUGGUGGCUUAGA------------------------------------------------ 109 1,1 -----------UGGUUUCACAUGGUGGCUUAGAa----------------------------------------------- 2 1,1 -----------UGGUUUCACAUGGUGGCUUAGAU----------------------------------------------- 88 1,2 -----------UGGUUUCACAUGGUGGCUUAGAUU---------------------------------------------- 2 1,3 --------------------------------------------------CUAGCACCAUUUGAAAUCA------------ 90 -1,-5 --------------------------------------------------CUAGCACCAUUUGAAAUCAuu---------- 2 -1,-5 --------------------------------------------------CUAGCACCAUUUGAAAUCAG----------- 233 -1,-4 --------------------------------------------------CUAGCACCAUUUGAAAUCAGa---------- 4 -1,-4 --------------------------------------------------CUAGCACCAUUUGAAAUCAGg---------- 2 -1,-4 --------------------------------------------------CUAGCACCAUUUGAAAUCAGU---------- 2444 -1,-3 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUa--------- 42 -1,-3 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUaa-------- 2 -1,-3 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUau-------- 4 -1,-3 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUc--------- 4 -1,-3 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUu--------- 243 -1,-3 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUuu-------- 26 -1,-3 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUG--------- 4861 -1,-2 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUGa-------- 991 -1,-2 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUGaa------- 6 -1,-2 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUGau------- 4 -1,-2 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUGc-------- 2 -1,-2 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUGg-------- 8 -1,-2 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUGU-------- 6034 -1,-1 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUGUa------- 14 -1,-1 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUGUU------- 287 -1,0 --------------------------------------------------CUAGCACCAUUUGAAAUCAGUGUUU------ 2 -1,1 ---------------------------------------------------UAGCACCAUUUGAAAUCA------------ 526 0,-5 ---------------------------------------------------UAGCACCAUUUGAAAUCAa----------- 2 0,-5 ---------------------------------------------------UAGCACCAUUUGAAAUCAau---------- 5 0,-5 ---------------------------------------------------UAGCACCAUUUGAAAUCAuu---------- 2 0,-5 ---------------------------------------------------UAGCACCAUUUGAAAUCAG----------- 1210 0,-4 ---------------------------------------------------UAGCACCAUUUGAAAUCAGa---------- 90 0,-4 ---------------------------------------------------UAGCACCAUUUGAAAUCAGc---------- 7 0,-4 ---------------------------------------------------UAGCACCAUUUGAAAUCAGU---------- 6254 0,-3 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUa--------- 93 0,-3 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUaa-------- 34 0,-3 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUau-------- 51 0,-3 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUc--------- 4 0,-3 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUu--------- 334 0,-3 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUuu-------- 197 0,-3 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUG--------- 13292 0,-2 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGa-------- 5560 0,-2 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGaa------- 326 0,-2 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGau------- 89 0,-2 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGc-------- 82 0,-2 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGg-------- 57 0,-2 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGU-------- 35342 0,-1 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUa------- 1422 0,-1 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUaa------ 93 0,-1 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUau------ 9 0,-1 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUc------- 129 0,-1 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUg------- 11 0,-1 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUU------- 99937 0,0 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUUa------ 368 0,0 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUUaa----- 2 0,0 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUUg------ 311 0,0 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUUU------ 1548 0,1 ---------------------------------------------------UAGCACCAUUUGAAAUCAGUGUUUU----- 22 0,2 ----------------------------------------------------AGCACCAUUUGAAAUCAG----------- 27 1,-4 ----------------------------------------------------AGCACCAUUUGAAAUCAGU---------- 193 1,-3 ----------------------------------------------------AGCACCAUUUGAAAUCAGUu--------- 2 1,-3 ----------------------------------------------------AGCACCAUUUGAAAUCAGUuu-------- 4 1,-3 ----------------------------------------------------AGCACCAUUUGAAAUCAGUG--------- 563 1,-2 ----------------------------------------------------AGCACCAUUUGAAAUCAGUGa-------- 228 1,-2 ----------------------------------------------------AGCACCAUUUGAAAUCAGUGaa------- 9 1,-2 ----------------------------------------------------AGCACCAUUUGAAAUCAGUGg-------- 2 1,-2 ----------------------------------------------------AGCACCAUUUGAAAUCAGUGU-------- 1575 1,-1 ----------------------------------------------------AGCACCAUUUGAAAUCAGUGUa------- 38 1,-1 ----------------------------------------------------AGCACCAUUUGAAAUCAGUGUU------- 4439 1,0 ----------------------------------------------------AGCACCAUUUGAAAUCAGUGUUa------ 10 1,0 ----------------------------------------------------AGCACCAUUUGAAAUCAGUGUUg------ 2 1,0 ----------------------------------------------------AGCACCAUUUGAAAUCAGUGUUU------ 55 1,1 -----------------------------------------------------GCACCAUUUGAAAUCAGUG--------- 10 2,-2 -----------------------------------------------------GCACCAUUUGAAAUCAGUGa-------- 2 2,-2 -----------------------------------------------------GCACCAUUUGAAAUCAGUGU-------- 58 2,-1 -----------------------------------------------------GCACCAUUUGAAAUCAGUGUU------- 207 2,0 -----------------------------------------------------GCACCAUUUGAAAUCAGUGUUU------ 2 2,1 >hsa-mir-29c mi:16-37;MA:54-75 Tumor aucucuuacacaggcUGACCGAUUUCUCCUGGUGUUCagagucuguuuuugucUAGCACCAUUUGAAAUCGGUUAugauguaggggga ---------------UGACCGAUUUCUCCUGGU------------------------------------------------------- 2 0,-4 ---------------UGACCGAUUUCUCCUGGUG------------------------------------------------------ 18 0,-3 ---------------UGACCGAUUUCUCCUGGUGa----------------------------------------------------- 15 0,-3 ---------------UGACCGAUUUCUCCUGGUGU----------------------------------------------------- 146 0,-2 ---------------UGACCGAUUUCUCCUGGUGUaa--------------------------------------------------- 9 0,-2 ---------------UGACCGAUUUCUCCUGGUGUU---------------------------------------------------- 1440 0,-1 ---------------UGACCGAUUUCUCCUGGUGUUa--------------------------------------------------- 262 0,-1 ---------------UGACCGAUUUCUCCUGGUGUUaa-------------------------------------------------- 16 0,-1 ---------------UGACCGAUUUCUCCUGGUGUUg--------------------------------------------------- 4 0,-1 ---------------UGACCGAUUUCUCCUGGUGUUu--------------------------------------------------- 151 0,-1 ---------------UGACCGAUUUCUCCUGGUGUUC--------------------------------------------------- 604 0,0 ---------------UGACCGAUUUCUCCUGGUGUUCu-------------------------------------------------- 103 0,0 ---------------UGACCGAUUUCUCCUGGUGUUCA-------------------------------------------------- 142 0,1 ---------------UGACCGAUUUCUCCUGGUGUUCAG------------------------------------------------- 33 0,2 ---------------UGACCGAUUUCUCCUGGUGUUCAGu------------------------------------------------ 2 0,2 ---------------UGACCGAUUUCUCCUGGUGUUCAGA------------------------------------------------ 10 0,3 ----------------GACCGAUUUCUCCUGGUG------------------------------------------------------ 4 1,-3 ----------------GACCGAUUUCUCCUGGUGU----------------------------------------------------- 33 1,-2 ----------------GACCGAUUUCUCCUGGUGUU---------------------------------------------------- 434 1,-1 ----------------GACCGAUUUCUCCUGGUGUUa--------------------------------------------------- 56 1,-1 ----------------GACCGAUUUCUCCUGGUGUUaa-------------------------------------------------- 5 1,-1 ----------------GACCGAUUUCUCCUGGUGUUu--------------------------------------------------- 21 1,-1 ----------------GACCGAUUUCUCCUGGUGUUC--------------------------------------------------- 365 1,0 ----------------GACCGAUUUCUCCUGGUGUUCu-------------------------------------------------- 2 1,0 ----------------GACCGAUUUCUCCUGGUGUUCA-------------------------------------------------- 352 1,1 ----------------GACCGAUUUCUCCUGGUGUUCAa------------------------------------------------- 2 1,1 ----------------GACCGAUUUCUCCUGGUGUUCAG------------------------------------------------- 139 1,2 ----------------GACCGAUUUCUCCUGGUGUUCAGu------------------------------------------------ 7 1,2 ----------------GACCGAUUUCUCCUGGUGUUCAGA------------------------------------------------ 51 1,3 -----------------ACCGAUUUCUCCUGGUGUU---------------------------------------------------- 47 2,-1 -----------------ACCGAUUUCUCCUGGUGUUa--------------------------------------------------- 3 2,-1 -----------------ACCGAUUUCUCCUGGUGUUC--------------------------------------------------- 64 2,0 -----------------ACCGAUUUCUCCUGGUGUUCA-------------------------------------------------- 168 2,1 -----------------ACCGAUUUCUCCUGGUGUUCAG------------------------------------------------- 200 2,2 -----------------ACCGAUUUCUCCUGGUGUUCAGu------------------------------------------------ 15 2,2 -----------------ACCGAUUUCUCCUGGUGUUCAGA------------------------------------------------ 791 2,3 -----------------ACCGAUUUCUCCUGGUGUUCAGAa----------------------------------------------- 6 2,3 -----------------ACCGAUUUCUCCUGGUGUUCAGAu----------------------------------------------- 2 2,3 ---------------------------------------------------UCUAGCACCAUUUGAAAUCGGU--------------- 2 -2,-2 ---------------------------------------------------UCUAGCACCAUUUGAAAUCGGUU-------------- 8 -2,-1 ----------------------------------------------------CUAGCACCAUUUGAAAUC------------------ 16 -1,-5 ----------------------------------------------------CUAGCACCAUUUGAAAUCGG---------------- 2 -1,-3 ----------------------------------------------------CUAGCACCAUUUGAAAUCGGU--------------- 130 -1,-2 ----------------------------------------------------CUAGCACCAUUUGAAAUCGGUa-------------- 10 -1,-2 ----------------------------------------------------CUAGCACCAUUUGAAAUCGGUU-------------- 701 -1,-1 ----------------------------------------------------CUAGCACCAUUUGAAAUCGGUUu------------- 26 -1,-1 ----------------------------------------------------CUAGCACCAUUUGAAAUCGGUUA------------- 173 -1,0 ----------------------------------------------------CUAGCACCAUUUGAAAUCGGUUAa------------ 40 -1,0 ----------------------------------------------------CUAGCACCAUUUGAAAUCGGUUAU------------ 17 -1,1 -----------------------------------------------------UAGCACCAUUUGAAAUCG----------------- 543 0,-4 -----------------------------------------------------UAGCACCAUUUGAAAUCGa---------------- 39 0,-4 -----------------------------------------------------UAGCACCAUUUGAAAUCGau--------------- 32 0,-4 -----------------------------------------------------UAGCACCAUUUGAAAUCGuu--------------- 30 0,-4 -----------------------------------------------------UAGCACCAUUUGAAAUCGG---------------- 2188 0,-3 -----------------------------------------------------UAGCACCAUUUGAAAUCGGa--------------- 349 0,-3 -----------------------------------------------------UAGCACCAUUUGAAAUCGGaa-------------- 50 0,-3 -----------------------------------------------------UAGCACCAUUUGAAAUCGGau-------------- 34 0,-3 -----------------------------------------------------UAGCACCAUUUGAAAUCGGc--------------- 41 0,-3 -----------------------------------------------------UAGCACCAUUUGAAAUCGGg--------------- 16 0,-3 -----------------------------------------------------UAGCACCAUUUGAAAUCGGU--------------- 17860 0,-2 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUa-------------- 1950 0,-2 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUaa------------- 793 0,-2 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUau------------- 72 0,-2 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUc-------------- 85 0,-2 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUg-------------- 40 0,-2 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUU-------------- 74358 0,-1 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUc------------- 156 0,-1 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUg------------- 100 0,-1 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUu------------- 2794 0,-1 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUuu------------ 315 0,-1 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUA------------- 28626 0,0 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUAa------------ 9619 0,0 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUAaa----------- 271 0,0 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUAau----------- 50 0,0 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUAc------------ 125 0,0 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUAg------------ 222 0,0 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUAU------------ 3730 0,1 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUAUa----------- 9 0,1 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUAUu----------- 76 0,1 -----------------------------------------------------UAGCACCAUUUGAAAUCGGUUAUuu---------- 2 0,1 ------------------------------------------------------AGCACCAUUUGAAAUCGG---------------- 46 1,-3 ------------------------------------------------------AGCACCAUUUGAAAUCGGa--------------- 2 1,-3 ------------------------------------------------------AGCACCAUUUGAAAUCGGU--------------- 615 1,-2 ------------------------------------------------------AGCACCAUUUGAAAUCGGUa-------------- 52 1,-2 ------------------------------------------------------AGCACCAUUUGAAAUCGGUaa------------- 19 1,-2 ------------------------------------------------------AGCACCAUUUGAAAUCGGUau------------- 2 1,-2 ------------------------------------------------------AGCACCAUUUGAAAUCGGUc-------------- 2 1,-2 ------------------------------------------------------AGCACCAUUUGAAAUCGGUU-------------- 2838 1,-1 ------------------------------------------------------AGCACCAUUUGAAAUCGGUUc------------- 4 1,-1 ------------------------------------------------------AGCACCAUUUGAAAUCGGUUu------------- 78 1,-1 ------------------------------------------------------AGCACCAUUUGAAAUCGGUUuu------------ 6 1,-1 ------------------------------------------------------AGCACCAUUUGAAAUCGGUUA------------- 1084 1,0 ------------------------------------------------------AGCACCAUUUGAAAUCGGUUAa------------ 417 1,0 ------------------------------------------------------AGCACCAUUUGAAAUCGGUUAaa----------- 4 1,0 ------------------------------------------------------AGCACCAUUUGAAAUCGGUUAau----------- 2 1,0 ------------------------------------------------------AGCACCAUUUGAAAUCGGUUAU------------ 113 1,1 -------------------------------------------------------GCACCAUUUGAAAUCGGU--------------- 9 2,-2 -------------------------------------------------------GCACCAUUUGAAAUCGGUaa------------- 2 2,-2 -------------------------------------------------------GCACCAUUUGAAAUCGGUU-------------- 116 2,-1 -------------------------------------------------------GCACCAUUUGAAAUCGGUUA------------- 43 2,0 -------------------------------------------------------GCACCAUUUGAAAUCGGUUAa------------ 8 2,0 -------------------------------------------------------GCACCAUUUGAAAUCGGUUAau----------- 2 2,0 -------------------------------------------------------GCACCAUUUGAAAUCGGUUAU------------ 19 2,1 -------------------------------------------------------GCACCAUUUGAAAUCGGUUAUu----------- 89 2,1 -------------------------------------------------------GCACCAUUUGAAAUCGGUUAUG----------- 6 2,2 >hsa-mir-301a 3pM:51-73 Tumor acugcuaacgaaugcucugacuuuauugcacuacuguacuuuacagcuagCAGUGCAAUAGUAUUGUCAAAGCaucugaaagcagg -------------GCUCUGACUUUAUUGCACU------------------------------------------------------ 4 -------------GCUCUGACUUUAUUGCACUAC---------------------------------------------------- 2 -------------GCUCUGACUUUAUUGCACUACU--------------------------------------------------- 51 --------------------------------------------------CAGUGCAAUAGUAUUGUC------------------ 51 0,-5 --------------------------------------------------CAGUGCAAUAGUAUUGUCu----------------- 2 0,-5 --------------------------------------------------CAGUGCAAUAGUAUUGUCA----------------- 209 0,-4 --------------------------------------------------CAGUGCAAUAGUAUUGUCAA---------------- 61 0,-3 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAA--------------- 223 0,-2 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAa-------------- 33 0,-2 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAu-------------- 2 0,-2 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAuu------------- 2 0,-2 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAG-------------- 3120 0,-1 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAGa------------- 168 0,-1 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAGaa------------ 10 0,-1 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAGu------------- 43 0,-1 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAGC------------- 5197 0,0 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAGCg------------ 2 0,0 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAGCu------------ 19 0,0 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAGCA------------ 919 0,1 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAGCAa----------- 4 0,1 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAGCAc----------- 2 0,1 --------------------------------------------------CAGUGCAAUAGUAUUGUCAAAGCAU----------- 1124 0,2 ---------------------------------------------------AGUGCAAUAGUAUUGUCA----------------- 5 1,-4 ---------------------------------------------------AGUGCAAUAGUAUUGUCAAA--------------- 4 1,-2 ---------------------------------------------------AGUGCAAUAGUAUUGUCAAAG-------------- 112 1,-1 ---------------------------------------------------AGUGCAAUAGUAUUGUCAAAGa------------- 4 1,-1 ---------------------------------------------------AGUGCAAUAGUAUUGUCAAAGC------------- 310 1,0 ---------------------------------------------------AGUGCAAUAGUAUUGUCAAAGCA------------ 34 1,1 ---------------------------------------------------AGUGCAAUAGUAUUGUCAAAGCAU----------- 35 1,2 ---------------------------------------------------AGUGCAAUAGUAUUGUCAAAGCAUu---------- 5 1,2 ----------------------------------------------------GUGCAAUAGUAUUGUCAAAG-------------- 2 2,-1 ----------------------------------------------------GUGCAAUAGUAUUGUCAAAGC------------- 5 2,0 ----------------------------------------------------GUGCAAUAGUAUUGUCAAAGCA------------ 3 2,1 >hsa-mir-301b 3pM:45-67 Tumor gccgcaggugcucugacgagguugcacuacugugcucugagaagCAGUGCAAUGAUAUUGUCAAAGCaucugggacca --------------------------------------------CAGUGCAAUGAUAUUGUCA--------------- 89 0,-4 --------------------------------------------CAGUGCAAUGAUAUUGUCAA-------------- 17 0,-3 --------------------------------------------CAGUGCAAUGAUAUUGUCAAA------------- 32 0,-2 --------------------------------------------CAGUGCAAUGAUAUUGUCAAAu------------ 2 0,-2 --------------------------------------------CAGUGCAAUGAUAUUGUCAAAG------------ 339 0,-1 --------------------------------------------CAGUGCAAUGAUAUUGUCAAAGa----------- 2 0,-1 --------------------------------------------CAGUGCAAUGAUAUUGUCAAAGC----------- 545 0,0 --------------------------------------------CAGUGCAAUGAUAUUGUCAAAGCu---------- 3 0,0 --------------------------------------------CAGUGCAAUGAUAUUGUCAAAGCA---------- 68 0,1 --------------------------------------------CAGUGCAAUGAUAUUGUCAAAGCAa--------- 2 0,1 --------------------------------------------CAGUGCAAUGAUAUUGUCAAAGCAU--------- 15 0,2 ---------------------------------------------AGUGCAAUGAUAUUGUCAAA------------- 2 1,-2 ---------------------------------------------AGUGCAAUGAUAUUGUCAAAG------------ 10 1,-1 ---------------------------------------------AGUGCAAUGAUAUUGUCAAAGC----------- 30 1,0 ---------------------------------------------AGUGCAAUGAUAUUGUCAAAGCA---------- 2 1,1 >hsa-mir-3064 5p:13-33;3p:53-75 Tumor uuuuauuuuuggUCUGGCUGUUGUGGUGUGCAAaacuccguacauugcuauuUUGCCACACUGCAACACCUUACAgauguggaa ------------UCUGGCUGUUGUGGUGUGCAA--------------------------------------------------- 2 0,0 ---------------------------------------------------UUUGCCACACUGCAACACCU------------- 2 -1,-4 ---------------------------------------------------UUUGCCACACUGCAACACCUUA----------- 2 -1,-2 ----------------------------------------------------UUGCCACACUGCAACACCUUAC---------- 2 0,-1 >hsa-mir-3065 5p:10-32;3p:50-72 Tumor cugcccucuUCAACAAAAUCACUGAUGCUGGAgucgccugagucaucacUCAGCACCAGGAUAUUGUUGGAGaggacag ---------UCAACAAAAUCACUGAUG---------------------------------------------------- 2 0,-5 ---------UCAACAAAAUCACUGAUGCUG------------------------------------------------- 18 0,-2 ---------UCAACAAAAUCACUGAUGCUGG------------------------------------------------ 166 0,-1 ---------UCAACAAAAUCACUGAUGCUGGA----------------------------------------------- 203 0,0 ---------UCAACAAAAUCACUGAUGCUGGAa---------------------------------------------- 6 0,0 ---------UCAACAAAAUCACUGAUGCUGGAG---------------------------------------------- 15 0,1 ---------UCAACAAAAUCACUGAUGCUGGAGU--------------------------------------------- 42 0,2 -------------------------------------------------UCAGCACCAGGAUAUUGUUGG--------- 8 0,-2 -------------------------------------------------UCAGCACCAGGAUAUUGUUGGA-------- 105 0,-1 -------------------------------------------------UCAGCACCAGGAUAUUGUUGGAa------- 6 0,-1 -------------------------------------------------UCAGCACCAGGAUAUUGUUGGAG------- 31 0,0 -------------------------------------------------UCAGCACCAGGAUAUUGUUGGAGu------ 19 0,0 >hsa-mir-3074 5p:12-32;3p:50-71 Tumor gcucgacuccuGUUCCUGCUGAACUGAGCCAGuguguaaaaugagaacuGAUAUCAGCUCAGUAGGCACCGgagggcgggu -----------GUUCCUGCUGAACUGAGCCAGU------------------------------------------------ 24 0,1 ------------UUCCUGCUGAACUGAGCCAGU------------------------------------------------ 24 1,1 -------------------------------------------------GAUAUCAGCUCAGUAGGCAC------------ 2 0,-2 -------------------------------------------------GAUAUCAGCUCAGUAGGCACCG---------- 6 0,0 -------------------------------------------------GAUAUCAGCUCAGUAGGCACCGu--------- 11 0,0 >hsa-mir-30a MA:6-27;mi:47-68 Tumor gcgacUGUAAACAUCCUCGACUGGAAGcugugaagccacagaugggCUUUCAGUCGGAUGUUUGCAGCugc ----CUGUAAACAUCCUCGACUGGA---------------------------------------------- 2 -1,-2 ----CUGUAAACAUCCUCGACUGGAA--------------------------------------------- 9 -1,-1 ----CUGUAAACAUCCUCGACUGGAAG-------------------------------------------- 23 -1,0 ----CUGUAAACAUCCUCGACUGGAAGuu------------------------------------------ 2 -1,0 ----CUGUAAACAUCCUCGACUGGAAGC------------------------------------------- 21 -1,1 ----CUGUAAACAUCCUCGACUGGAAGCU------------------------------------------ 35 -1,2 -----UGUAAACAUCCUCGACUG------------------------------------------------ 731 0,-4 -----UGUAAACAUCCUCGACUGa----------------------------------------------- 42 0,-4 -----UGUAAACAUCCUCGACUGaa---------------------------------------------- 39 0,-4 -----UGUAAACAUCCUCGACUGu----------------------------------------------- 14 0,-4 -----UGUAAACAUCCUCGACUGG----------------------------------------------- 2842 0,-3 -----UGUAAACAUCCUCGACUGGc---------------------------------------------- 68 0,-3 -----UGUAAACAUCCUCGACUGGg---------------------------------------------- 11 0,-3 -----UGUAAACAUCCUCGACUGGu---------------------------------------------- 26 0,-3 -----UGUAAACAUCCUCGACUGGA---------------------------------------------- 22153 0,-2 -----UGUAAACAUCCUCGACUGGAc--------------------------------------------- 103 0,-2 -----UGUAAACAUCCUCGACUGGAg--------------------------------------------- 86 0,-2 -----UGUAAACAUCCUCGACUGGAu--------------------------------------------- 117 0,-2 -----UGUAAACAUCCUCGACUGGAuu-------------------------------------------- 2 0,-2 -----UGUAAACAUCCUCGACUGGAA--------------------------------------------- 26268 0,-1 -----UGUAAACAUCCUCGACUGGAAa-------------------------------------------- 6551 0,-1 -----UGUAAACAUCCUCGACUGGAAaa------------------------------------------- 304 0,-1 -----UGUAAACAUCCUCGACUGGAAau------------------------------------------- 45 0,-1 -----UGUAAACAUCCUCGACUGGAAc-------------------------------------------- 90 0,-1 -----UGUAAACAUCCUCGACUGGAAu-------------------------------------------- 551 0,-1 -----UGUAAACAUCCUCGACUGGAAuu------------------------------------------- 10 0,-1 -----UGUAAACAUCCUCGACUGGAAG-------------------------------------------- 47752 0,0 -----UGUAAACAUCCUCGACUGGAAGa------------------------------------------- 4753 0,0 -----UGUAAACAUCCUCGACUGGAAGaa------------------------------------------ 65 0,0 -----UGUAAACAUCCUCGACUGGAAGau------------------------------------------ 440 0,0 -----UGUAAACAUCCUCGACUGGAAGg------------------------------------------- 116 0,0 -----UGUAAACAUCCUCGACUGGAAGu------------------------------------------- 3122 0,0 -----UGUAAACAUCCUCGACUGGAAGuu------------------------------------------ 307 0,0 -----UGUAAACAUCCUCGACUGGAAGC------------------------------------------- 48488 0,1 -----UGUAAACAUCCUCGACUGGAAGCa------------------------------------------ 1353 0,1 -----UGUAAACAUCCUCGACUGGAAGCaa----------------------------------------- 8 0,1 -----UGUAAACAUCCUCGACUGGAAGCau----------------------------------------- 23 0,1 -----UGUAAACAUCCUCGACUGGAAGCc------------------------------------------ 261 0,1 -----UGUAAACAUCCUCGACUGGAAGCg------------------------------------------ 105 0,1 -----UGUAAACAUCCUCGACUGGAAGCU------------------------------------------ 72044 0,2 -----UGUAAACAUCCUCGACUGGAAGCUa----------------------------------------- 211 0,2 -----UGUAAACAUCCUCGACUGGAAGCUc----------------------------------------- 4 0,2 -----UGUAAACAUCCUCGACUGGAAGCUu----------------------------------------- 2548 0,2 -----UGUAAACAUCCUCGACUGGAAGCUG----------------------------------------- 4 0,3 ------GUAAACAUCCUCGACUGG----------------------------------------------- 55 1,-3 ------GUAAACAUCCUCGACUGGg---------------------------------------------- 3 1,-3 ------GUAAACAUCCUCGACUGGA---------------------------------------------- 372 1,-2 ------GUAAACAUCCUCGACUGGAA--------------------------------------------- 409 1,-1 ------GUAAACAUCCUCGACUGGAAa-------------------------------------------- 117 1,-1 ------GUAAACAUCCUCGACUGGAAaa------------------------------------------- 6 1,-1 ------GUAAACAUCCUCGACUGGAAu-------------------------------------------- 5 1,-1 ------GUAAACAUCCUCGACUGGAAG-------------------------------------------- 1192 1,0 ------GUAAACAUCCUCGACUGGAAGa------------------------------------------- 64 1,0 ------GUAAACAUCCUCGACUGGAAGau------------------------------------------ 5 1,0 ------GUAAACAUCCUCGACUGGAAGu------------------------------------------- 29 1,0 ------GUAAACAUCCUCGACUGGAAGC------------------------------------------- 808 1,1 ------GUAAACAUCCUCGACUGGAAGCa------------------------------------------ 46 1,1 ------GUAAACAUCCUCGACUGGAAGCg------------------------------------------ 2 1,1 ------GUAAACAUCCUCGACUGGAAGCU------------------------------------------ 2976 1,2 ------GUAAACAUCCUCGACUGGAAGCUa----------------------------------------- 7 1,2 ------GUAAACAUCCUCGACUGGAAGCUau---------------------------------------- 2 1,2 ------GUAAACAUCCUCGACUGGAAGCUu----------------------------------------- 119 1,2 ------GUAAACAUCCUCGACUGGAAGCUuu---------------------------------------- 10 1,2 -------UAAACAUCCUCGACUGGAAGC------------------------------------------- 8 2,1 -------UAAACAUCCUCGACUGGAAGCU------------------------------------------ 14 2,2 ----------------------------------------------CUUUCAGUCGGAUGUUUG------- 104 0,-4 ----------------------------------------------CUUUCAGUCGGAUGUUUGa------ 30 0,-4 ----------------------------------------------CUUUCAGUCGGAUGUUUGaa----- 2 0,-4 ----------------------------------------------CUUUCAGUCGGAUGUUUGu------ 6 0,-4 ----------------------------------------------CUUUCAGUCGGAUGUUUGC------ 401 0,-3 ----------------------------------------------CUUUCAGUCGGAUGUUUGCc----- 8 0,-3 ----------------------------------------------CUUUCAGUCGGAUGUUUGCu----- 4 0,-3 ----------------------------------------------CUUUCAGUCGGAUGUUUGCA----- 1601 0,-2 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAa---- 298 0,-2 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAaa--- 24 0,-2 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAau--- 6 0,-2 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAc---- 2 0,-2 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAu---- 33 0,-2 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAuu--- 25 0,-2 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAG---- 3562 0,-1 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGa--- 378 0,-1 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGaa-- 41 0,-1 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGg--- 6 0,-1 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGu--- 4781 0,-1 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGuu-- 212 0,-1 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGC--- 5772 0,0 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGCa-- 613 0,0 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGCaa- 6 0,0 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGCau- 43 0,0 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGCc-- 12 0,0 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGCg-- 6 0,0 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGCU-- 117 0,1 ----------------------------------------------CUUUCAGUCGGAUGUUUGCAGCUu- 11 0,1 -----------------------------------------------UUUCAGUCGGAUGUUUGC------ 22 1,-3 -----------------------------------------------UUUCAGUCGGAUGUUUGCA----- 117 1,-2 -----------------------------------------------UUUCAGUCGGAUGUUUGCAa---- 41 1,-2 -----------------------------------------------UUUCAGUCGGAUGUUUGCAaa--- 7 1,-2 -----------------------------------------------UUUCAGUCGGAUGUUUGCAuu--- 6 1,-2 -----------------------------------------------UUUCAGUCGGAUGUUUGCAG---- 670 1,-1 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGa--- 40 1,-1 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGaa-- 7 1,-1 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGu--- 1356 1,-1 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGuu-- 302 1,-1 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGC--- 943 1,0 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGCa-- 124 1,0 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGCaa- 8 1,0 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGCau- 12 1,0 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGCc-- 4 1,0 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGCU-- 366 1,1 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGCUa- 14 1,1 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGCUu- 34 1,1 -----------------------------------------------UUUCAGUCGGAUGUUUGCAGCUG- 2 1,2 ------------------------------------------------UUCAGUCGGAUGUUUGCAG---- 12 2,-1 ------------------------------------------------UUCAGUCGGAUGUUUGCAGa--- 2 2,-1 ------------------------------------------------UUCAGUCGGAUGUUUGCAGu--- 14 2,-1 ------------------------------------------------UUCAGUCGGAUGUUUGCAGuu-- 2 2,-1 ------------------------------------------------UUCAGUCGGAUGUUUGCAGC--- 39 2,0 ------------------------------------------------UUCAGUCGGAUGUUUGCAGCU-- 3 2,1 >hsa-mir-30b MA:17-38;mi:55-76 Tumor accaaguuucaguucaUGUAAACAUCCUACACUCAGCUguaauacauggauuggCUGGGAGGUGGAUGUUUACUUCagcugacuugga ---------------AUGUAAACAUCCUACACUCAGC--------------------------------------------------- 2 -1,-1 ---------------AUGUAAACAUCCUACACUCAGCU-------------------------------------------------- 33 -1,0 ----------------UGUAAACAUCCUACACUC------------------------------------------------------ 1497 0,-4 ----------------UGUAAACAUCCUACACUCA----------------------------------------------------- 838 0,-3 ----------------UGUAAACAUCCUACACUCAa---------------------------------------------------- 13 0,-3 ----------------UGUAAACAUCCUACACUCAG---------------------------------------------------- 691 0,-2 ----------------UGUAAACAUCCUACACUCAGa--------------------------------------------------- 680 0,-2 ----------------UGUAAACAUCCUACACUCAGaa-------------------------------------------------- 26 0,-2 ----------------UGUAAACAUCCUACACUCAGau-------------------------------------------------- 215 0,-2 ----------------UGUAAACAUCCUACACUCAGu--------------------------------------------------- 108 0,-2 ----------------UGUAAACAUCCUACACUCAGuu-------------------------------------------------- 104 0,-2 ----------------UGUAAACAUCCUACACUCAGC--------------------------------------------------- 20557 0,-1 ----------------UGUAAACAUCCUACACUCAGCa-------------------------------------------------- 317 0,-1 ----------------UGUAAACAUCCUACACUCAGCaa------------------------------------------------- 12 0,-1 ----------------UGUAAACAUCCUACACUCAGCau------------------------------------------------- 2 0,-1 ----------------UGUAAACAUCCUACACUCAGCc-------------------------------------------------- 226 0,-1 ----------------UGUAAACAUCCUACACUCAGCg-------------------------------------------------- 53 0,-1 ----------------UGUAAACAUCCUACACUCAGCU-------------------------------------------------- 102286 0,0 ----------------UGUAAACAUCCUACACUCAGCUa------------------------------------------------- 934 0,0 ----------------UGUAAACAUCCUACACUCAGCUaa------------------------------------------------ 50 0,0 ----------------UGUAAACAUCCUACACUCAGCUau------------------------------------------------ 141 0,0 ----------------UGUAAACAUCCUACACUCAGCUc------------------------------------------------- 6 0,0 ----------------UGUAAACAUCCUACACUCAGCUu------------------------------------------------- 1842 0,0 ----------------UGUAAACAUCCUACACUCAGCUuu------------------------------------------------ 132 0,0 ----------------UGUAAACAUCCUACACUCAGCUG------------------------------------------------- 170 0,1 ----------------UGUAAACAUCCUACACUCAGCUGa------------------------------------------------ 7 0,1 ----------------UGUAAACAUCCUACACUCAGCUGU------------------------------------------------ 14 0,2 -----------------GUAAACAUCCUACACUCA----------------------------------------------------- 4 1,-3 -----------------GUAAACAUCCUACACUCAG---------------------------------------------------- 3 1,-2 -----------------GUAAACAUCCUACACUCAGa--------------------------------------------------- 8 1,-2 -----------------GUAAACAUCCUACACUCAGC--------------------------------------------------- 529 1,-1 -----------------GUAAACAUCCUACACUCAGCa-------------------------------------------------- 4 1,-1 -----------------GUAAACAUCCUACACUCAGCU-------------------------------------------------- 2503 1,0 -----------------GUAAACAUCCUACACUCAGCUa------------------------------------------------- 7 1,0 -----------------GUAAACAUCCUACACUCAGCUu------------------------------------------------- 28 1,0 -----------------GUAAACAUCCUACACUCAGCUG------------------------------------------------- 2 1,1 ------------------UAAACAUCCUACACUCAGCU-------------------------------------------------- 7 2,0 ------------------------------------------------------CUGGGAGGUGGAUGUUUACU-------------- 25 0,-2 ------------------------------------------------------CUGGGAGGUGGAUGUUUACUU------------- 25 0,-1 ------------------------------------------------------CUGGGAGGUGGAUGUUUACUUC------------ 119 0,0 ------------------------------------------------------CUGGGAGGUGGAUGUUUACUUCu----------- 6 0,0 ------------------------------------------------------CUGGGAGGUGGAUGUUUACUUCA----------- 4 0,1 -------------------------------------------------------UGGGAGGUGGAUGUUUACUUC------------ 2 1,0 >hsa-mir-30c-1 MA:17-39;mi:56-77 Tumor accaugcuguagugugUGUAAACAUCCUACACUCUCAGCugugagcucaagguggCUGGGAGAGGGUUGUUUACUCCuucugccaugga ----------------UGUAAACAUCCUACACUC------------------------------------------------------- 1497 0,-5 ----------------UGUAAACAUCCUACACUCU------------------------------------------------------ 1365 0,-4 ----------------UGUAAACAUCCUACACUCUa----------------------------------------------------- 4 0,-4 ----------------UGUAAACAUCCUACACUCUaa---------------------------------------------------- 12 0,-4 ----------------UGUAAACAUCCUACACUCUu----------------------------------------------------- 5 0,-4 ----------------UGUAAACAUCCUACACUCUC----------------------------------------------------- 2199 0,-3 ----------------UGUAAACAUCCUACACUCUCc---------------------------------------------------- 110 0,-3 ----------------UGUAAACAUCCUACACUCUCg---------------------------------------------------- 2 0,-3 ----------------UGUAAACAUCCUACACUCUCu---------------------------------------------------- 57 0,-3 ----------------UGUAAACAUCCUACACUCUCA---------------------------------------------------- 7618 0,-2 ----------------UGUAAACAUCCUACACUCUCAa--------------------------------------------------- 170 0,-2 ----------------UGUAAACAUCCUACACUCUCAaa-------------------------------------------------- 14 0,-2 ----------------UGUAAACAUCCUACACUCUCAau-------------------------------------------------- 18 0,-2 ----------------UGUAAACAUCCUACACUCUCAc--------------------------------------------------- 5 0,-2 ----------------UGUAAACAUCCUACACUCUCAu--------------------------------------------------- 54 0,-2 ----------------UGUAAACAUCCUACACUCUCAuu-------------------------------------------------- 2 0,-2 ----------------UGUAAACAUCCUACACUCUCAG--------------------------------------------------- 6834 0,-1 ----------------UGUAAACAUCCUACACUCUCAGa-------------------------------------------------- 3415 0,-1 ----------------UGUAAACAUCCUACACUCUCAGaa------------------------------------------------- 84 0,-1 ----------------UGUAAACAUCCUACACUCUCAGau------------------------------------------------- 95 0,-1 ----------------UGUAAACAUCCUACACUCUCAGg-------------------------------------------------- 14 0,-1 ----------------UGUAAACAUCCUACACUCUCAGu-------------------------------------------------- 1133 0,-1 ----------------UGUAAACAUCCUACACUCUCAGuu------------------------------------------------- 78 0,-1 ----------------UGUAAACAUCCUACACUCUCAGC-------------------------------------------------- 26314 0,0 ----------------UGUAAACAUCCUACACUCUCAGCa------------------------------------------------- 575 0,0 ----------------UGUAAACAUCCUACACUCUCAGCaa------------------------------------------------ 22 0,0 ----------------UGUAAACAUCCUACACUCUCAGCau------------------------------------------------ 11 0,0 ----------------UGUAAACAUCCUACACUCUCAGCc------------------------------------------------- 105 0,0 ----------------UGUAAACAUCCUACACUCUCAGCg------------------------------------------------- 62 0,0 ----------------UGUAAACAUCCUACACUCUCAGCU------------------------------------------------- 46199 0,1 ----------------UGUAAACAUCCUACACUCUCAGCUa------------------------------------------------ 343 0,1 ----------------UGUAAACAUCCUACACUCUCAGCUu------------------------------------------------ 1007 0,1 ----------------UGUAAACAUCCUACACUCUCAGCUG------------------------------------------------ 4 0,2 -----------------GUAAACAUCCUACACUCU------------------------------------------------------ 30 1,-4 -----------------GUAAACAUCCUACACUCUC----------------------------------------------------- 36 1,-3 -----------------GUAAACAUCCUACACUCUCc---------------------------------------------------- 2 1,-3 -----------------GUAAACAUCCUACACUCUCA---------------------------------------------------- 162 1,-2 -----------------GUAAACAUCCUACACUCUCAG--------------------------------------------------- 150 1,-1 -----------------GUAAACAUCCUACACUCUCAGa-------------------------------------------------- 78 1,-1 -----------------GUAAACAUCCUACACUCUCAGau------------------------------------------------- 2 1,-1 -----------------GUAAACAUCCUACACUCUCAGu-------------------------------------------------- 15 1,-1 -----------------GUAAACAUCCUACACUCUCAGC-------------------------------------------------- 867 1,0 -----------------GUAAACAUCCUACACUCUCAGCa------------------------------------------------- 4 1,0 -----------------GUAAACAUCCUACACUCUCAGCU------------------------------------------------- 1502 1,1 -----------------GUAAACAUCCUACACUCUCAGCUa------------------------------------------------ 6 1,1 -----------------GUAAACAUCCUACACUCUCAGCUu------------------------------------------------ 13 1,1 -------------------------------------------------------CUGGGAGAGGGUUGUUUAC--------------- 2 0,-3 -------------------------------------------------------CUGGGAGAGGGUUGUUUACU-------------- 14 0,-2 -------------------------------------------------------CUGGGAGAGGGUUGUUUACUuu------------ 2 0,-2 -------------------------------------------------------CUGGGAGAGGGUUGUUUACUC------------- 14 0,-1 -------------------------------------------------------CUGGGAGAGGGUUGUUUACUCa------------ 2 0,-1 -------------------------------------------------------CUGGGAGAGGGUUGUUUACUCu------------ 28 0,-1 -------------------------------------------------------CUGGGAGAGGGUUGUUUACUCC------------ 85 0,0 -------------------------------------------------------CUGGGAGAGGGUUGUUUACUCCa----------- 6 0,0 -------------------------------------------------------CUGGGAGAGGGUUGUUUACUCCU----------- 9 0,1 >hsa-mir-30c-2 MA:7-29;mi:47-68 Tumor agauacUGUAAACAUCCUACACUCUCAGCuguggaaaguaagaaagCUGGGAGAAGGCUGUUUACUCUuucu -----CUGUAAACAUCCUACACUC------------------------------------------------ 445 -1,-5 -----CUGUAAACAUCCUACACUCUC---------------------------------------------- 2 -1,-3 -----CUGUAAACAUCCUACACUCUCA--------------------------------------------- 18 -1,-2 -----CUGUAAACAUCCUACACUCUCAG-------------------------------------------- 9 -1,-1 -----CUGUAAACAUCCUACACUCUCAGa------------------------------------------- 4 -1,-1 -----CUGUAAACAUCCUACACUCUCAGC------------------------------------------- 105 -1,0 -----CUGUAAACAUCCUACACUCUCAGCU------------------------------------------ 180 -1,1 ------UGUAAACAUCCUACACUC------------------------------------------------ 1497 0,-5 ------UGUAAACAUCCUACACUCU----------------------------------------------- 1365 0,-4 ------UGUAAACAUCCUACACUCUa---------------------------------------------- 4 0,-4 ------UGUAAACAUCCUACACUCUaa--------------------------------------------- 12 0,-4 ------UGUAAACAUCCUACACUCUu---------------------------------------------- 5 0,-4 ------UGUAAACAUCCUACACUCUC---------------------------------------------- 2199 0,-3 ------UGUAAACAUCCUACACUCUCc--------------------------------------------- 110 0,-3 ------UGUAAACAUCCUACACUCUCg--------------------------------------------- 2 0,-3 ------UGUAAACAUCCUACACUCUCu--------------------------------------------- 57 0,-3 ------UGUAAACAUCCUACACUCUCA--------------------------------------------- 7618 0,-2 ------UGUAAACAUCCUACACUCUCAa-------------------------------------------- 170 0,-2 ------UGUAAACAUCCUACACUCUCAaa------------------------------------------- 14 0,-2 ------UGUAAACAUCCUACACUCUCAau------------------------------------------- 18 0,-2 ------UGUAAACAUCCUACACUCUCAc-------------------------------------------- 5 0,-2 ------UGUAAACAUCCUACACUCUCAu-------------------------------------------- 54 0,-2 ------UGUAAACAUCCUACACUCUCAuu------------------------------------------- 2 0,-2 ------UGUAAACAUCCUACACUCUCAG-------------------------------------------- 6834 0,-1 ------UGUAAACAUCCUACACUCUCAGa------------------------------------------- 3415 0,-1 ------UGUAAACAUCCUACACUCUCAGaa------------------------------------------ 84 0,-1 ------UGUAAACAUCCUACACUCUCAGau------------------------------------------ 95 0,-1 ------UGUAAACAUCCUACACUCUCAGg------------------------------------------- 14 0,-1 ------UGUAAACAUCCUACACUCUCAGu------------------------------------------- 1133 0,-1 ------UGUAAACAUCCUACACUCUCAGuu------------------------------------------ 78 0,-1 ------UGUAAACAUCCUACACUCUCAGC------------------------------------------- 26314 0,0 ------UGUAAACAUCCUACACUCUCAGCa------------------------------------------ 575 0,0 ------UGUAAACAUCCUACACUCUCAGCaa----------------------------------------- 22 0,0 ------UGUAAACAUCCUACACUCUCAGCau----------------------------------------- 11 0,0 ------UGUAAACAUCCUACACUCUCAGCc------------------------------------------ 105 0,0 ------UGUAAACAUCCUACACUCUCAGCg------------------------------------------ 62 0,0 ------UGUAAACAUCCUACACUCUCAGCU------------------------------------------ 46199 0,1 ------UGUAAACAUCCUACACUCUCAGCUa----------------------------------------- 343 0,1 ------UGUAAACAUCCUACACUCUCAGCUu----------------------------------------- 1007 0,1 ------UGUAAACAUCCUACACUCUCAGCUG----------------------------------------- 4 0,2 -------GUAAACAUCCUACACUCU----------------------------------------------- 30 1,-4 -------GUAAACAUCCUACACUCUC---------------------------------------------- 36 1,-3 -------GUAAACAUCCUACACUCUCc--------------------------------------------- 2 1,-3 -------GUAAACAUCCUACACUCUCA--------------------------------------------- 162 1,-2 -------GUAAACAUCCUACACUCUCAG-------------------------------------------- 150 1,-1 -------GUAAACAUCCUACACUCUCAGa------------------------------------------- 78 1,-1 -------GUAAACAUCCUACACUCUCAGau------------------------------------------ 2 1,-1 -------GUAAACAUCCUACACUCUCAGu------------------------------------------- 15 1,-1 -------GUAAACAUCCUACACUCUCAGC------------------------------------------- 867 1,0 -------GUAAACAUCCUACACUCUCAGCa------------------------------------------ 4 1,0 -------GUAAACAUCCUACACUCUCAGCU------------------------------------------ 1502 1,1 -------GUAAACAUCCUACACUCUCAGCUa----------------------------------------- 6 1,1 -------GUAAACAUCCUACACUCUCAGCUu----------------------------------------- 13 1,1 ----------------------------------------------CUGGGAGAAGGCUGUUUA-------- 4 0,-4 ----------------------------------------------CUGGGAGAAGGCUGUUUAC------- 17 0,-3 ----------------------------------------------CUGGGAGAAGGCUGUUUACU------ 214 0,-2 ----------------------------------------------CUGGGAGAAGGCUGUUUACUC----- 70 0,-1 ----------------------------------------------CUGGGAGAAGGCUGUUUACUCa---- 7 0,-1 ----------------------------------------------CUGGGAGAAGGCUGUUUACUCU---- 1010 0,0 ----------------------------------------------CUGGGAGAAGGCUGUUUACUCUa--- 2 0,0 ----------------------------------------------CUGGGAGAAGGCUGUUUACUCUU--- 51 0,1 -----------------------------------------------UGGGAGAAGGCUGUUUACU------ 2 1,-2 -----------------------------------------------UGGGAGAAGGCUGUUUACUuu---- 2 1,-2 -----------------------------------------------UGGGAGAAGGCUGUUUACUC----- 2 1,-1 -----------------------------------------------UGGGAGAAGGCUGUUUACUCU---- 57 1,0 -----------------------------------------------UGGGAGAAGGCUGUUUACUCUa--- 2 1,0 -----------------------------------------------UGGGAGAAGGCUGUUUACUCUU--- 8 1,1 ------------------------------------------------GGGAGAAGGCUGUUUACUCU---- 2 2,0 >hsa-mir-30d MA:6-27;mi:46-67 Tumor guuguUGUAAACAUCCCCGACUGGAAGcuguaagacacagcuaagCUUUCAGUCAGAUGUUUGCUGCuac -----UGUAAACAUCCCCGACUG----------------------------------------------- 448 0,-4 -----UGUAAACAUCCCCGACUGa---------------------------------------------- 24 0,-4 -----UGUAAACAUCCCCGACUGaa--------------------------------------------- 41 0,-4 -----UGUAAACAUCCCCGACUGu---------------------------------------------- 27 0,-4 -----UGUAAACAUCCCCGACUGG---------------------------------------------- 2684 0,-3 -----UGUAAACAUCCCCGACUGGc--------------------------------------------- 61 0,-3 -----UGUAAACAUCCCCGACUGGg--------------------------------------------- 5 0,-3 -----UGUAAACAUCCCCGACUGGu--------------------------------------------- 10 0,-3 -----UGUAAACAUCCCCGACUGGA--------------------------------------------- 19338 0,-2 -----UGUAAACAUCCCCGACUGGAc-------------------------------------------- 88 0,-2 -----UGUAAACAUCCCCGACUGGAg-------------------------------------------- 100 0,-2 -----UGUAAACAUCCCCGACUGGAu-------------------------------------------- 144 0,-2 -----UGUAAACAUCCCCGACUGGAuu------------------------------------------- 2 0,-2 -----UGUAAACAUCCCCGACUGGAA-------------------------------------------- 21494 0,-1 -----UGUAAACAUCCCCGACUGGAAa------------------------------------------- 6710 0,-1 -----UGUAAACAUCCCCGACUGGAAaa------------------------------------------ 341 0,-1 -----UGUAAACAUCCCCGACUGGAAau------------------------------------------ 72 0,-1 -----UGUAAACAUCCCCGACUGGAAc------------------------------------------- 71 0,-1 -----UGUAAACAUCCCCGACUGGAAu------------------------------------------- 730 0,-1 -----UGUAAACAUCCCCGACUGGAAuu------------------------------------------ 4 0,-1 -----UGUAAACAUCCCCGACUGGAAG------------------------------------------- 32675 0,0 -----UGUAAACAUCCCCGACUGGAAGa------------------------------------------ 3712 0,0 -----UGUAAACAUCCCCGACUGGAAGaa----------------------------------------- 65 0,0 -----UGUAAACAUCCCCGACUGGAAGau----------------------------------------- 352 0,0 -----UGUAAACAUCCCCGACUGGAAGg------------------------------------------ 83 0,0 -----UGUAAACAUCCCCGACUGGAAGu------------------------------------------ 2814 0,0 -----UGUAAACAUCCCCGACUGGAAGuu----------------------------------------- 185 0,0 -----UGUAAACAUCCCCGACUGGAAGC------------------------------------------ 36308 0,1 -----UGUAAACAUCCCCGACUGGAAGCa----------------------------------------- 881 0,1 -----UGUAAACAUCCCCGACUGGAAGCaa---------------------------------------- 12 0,1 -----UGUAAACAUCCCCGACUGGAAGCau---------------------------------------- 19 0,1 -----UGUAAACAUCCCCGACUGGAAGCc----------------------------------------- 145 0,1 -----UGUAAACAUCCCCGACUGGAAGCg----------------------------------------- 85 0,1 -----UGUAAACAUCCCCGACUGGAAGCU----------------------------------------- 53934 0,2 -----UGUAAACAUCCCCGACUGGAAGCUa---------------------------------------- 195 0,2 -----UGUAAACAUCCCCGACUGGAAGCUc---------------------------------------- 4 0,2 -----UGUAAACAUCCCCGACUGGAAGCUu---------------------------------------- 1869 0,2 -----UGUAAACAUCCCCGACUGGAAGCUG---------------------------------------- 7 0,3 ------GUAAACAUCCCCGACUGG---------------------------------------------- 32 1,-3 ------GUAAACAUCCCCGACUGGA--------------------------------------------- 572 1,-2 ------GUAAACAUCCCCGACUGGAg-------------------------------------------- 4 1,-2 ------GUAAACAUCCCCGACUGGAA-------------------------------------------- 686 1,-1 ------GUAAACAUCCCCGACUGGAAa------------------------------------------- 188 1,-1 ------GUAAACAUCCCCGACUGGAAaa------------------------------------------ 7 1,-1 ------GUAAACAUCCCCGACUGGAAu------------------------------------------- 5 1,-1 ------GUAAACAUCCCCGACUGGAAG------------------------------------------- 1182 1,0 ------GUAAACAUCCCCGACUGGAAGa------------------------------------------ 131 1,0 ------GUAAACAUCCCCGACUGGAAGu------------------------------------------ 63 1,0 ------GUAAACAUCCCCGACUGGAAGuu----------------------------------------- 2 1,0 ------GUAAACAUCCCCGACUGGAAGC------------------------------------------ 1337 1,1 ------GUAAACAUCCCCGACUGGAAGCa----------------------------------------- 11 1,1 ------GUAAACAUCCCCGACUGGAAGCU----------------------------------------- 1734 1,2 ------GUAAACAUCCCCGACUGGAAGCUu---------------------------------------- 32 1,2 -------UAAACAUCCCCGACUGGAAG------------------------------------------- 2 2,0 -------UAAACAUCCCCGACUGGAAGC------------------------------------------ 6 2,1 ---------------------------------------------CUUUCAGUCAGAUGUUUG------- 2 0,-4 ---------------------------------------------CUUUCAGUCAGAUGUUUGC------ 8 0,-3 ---------------------------------------------CUUUCAGUCAGAUGUUUGCU----- 149 0,-2 ---------------------------------------------CUUUCAGUCAGAUGUUUGCUG---- 130 0,-1 ---------------------------------------------CUUUCAGUCAGAUGUUUGCUGa--- 6 0,-1 ---------------------------------------------CUUUCAGUCAGAUGUUUGCUGu--- 54 0,-1 ---------------------------------------------CUUUCAGUCAGAUGUUUGCUGuu-- 2 0,-1 ---------------------------------------------CUUUCAGUCAGAUGUUUGCUGC--- 641 0,0 ---------------------------------------------CUUUCAGUCAGAUGUUUGCUGCa-- 18 0,0 ---------------------------------------------CUUUCAGUCAGAUGUUUGCUGCU-- 166 0,1 ---------------------------------------------CUUUCAGUCAGAUGUUUGCUGCUu- 5 0,1 ----------------------------------------------UUUCAGUCAGAUGUUUGCU----- 11 1,-2 ----------------------------------------------UUUCAGUCAGAUGUUUGCUG---- 26 1,-1 ----------------------------------------------UUUCAGUCAGAUGUUUGCUGu--- 10 1,-1 ----------------------------------------------UUUCAGUCAGAUGUUUGCUGC--- 135 1,0 ----------------------------------------------UUUCAGUCAGAUGUUUGCUGCU-- 146 1,1 ----------------------------------------------UUUCAGUCAGAUGUUUGCUGCUu- 6 1,1 -----------------------------------------------UUCAGUCAGAUGUUUGCUG---- 3 2,-1 -----------------------------------------------UUCAGUCAGAUGUUUGCUGC--- 13 2,0 -----------------------------------------------UUCAGUCAGAUGUUUGCUGCa-- 2 2,0 >hsa-mir-30e MA:17-38;mi:59-80 Tumor gggcagucuuugcuacUGUAAACAUCCUUGACUGGAAGcuguaagguguucagaggagCUUUCAGUCGGAUGUUUACAGCggcaggcugcca ---------------CUGUAAACAUCCUUGACUGGA-------------------------------------------------------- 55 -1,-2 ---------------CUGUAAACAUCCUUGACUGGAA------------------------------------------------------- 13 -1,-1 ---------------CUGUAAACAUCCUUGACUGGAAG------------------------------------------------------ 21 -1,0 ---------------CUGUAAACAUCCUUGACUGGAAGC----------------------------------------------------- 7 -1,1 ---------------CUGUAAACAUCCUUGACUGGAAGCU---------------------------------------------------- 50 -1,2 ----------------UGUAAACAUCCUUGACUG---------------------------------------------------------- 472 0,-4 ----------------UGUAAACAUCCUUGACUGa--------------------------------------------------------- 28 0,-4 ----------------UGUAAACAUCCUUGACUGaa-------------------------------------------------------- 29 0,-4 ----------------UGUAAACAUCCUUGACUGu--------------------------------------------------------- 11 0,-4 ----------------UGUAAACAUCCUUGACUGG--------------------------------------------------------- 3425 0,-3 ----------------UGUAAACAUCCUUGACUGGc-------------------------------------------------------- 33 0,-3 ----------------UGUAAACAUCCUUGACUGGg-------------------------------------------------------- 9 0,-3 ----------------UGUAAACAUCCUUGACUGGu-------------------------------------------------------- 23 0,-3 ----------------UGUAAACAUCCUUGACUGGA-------------------------------------------------------- 20901 0,-2 ----------------UGUAAACAUCCUUGACUGGAc------------------------------------------------------- 46 0,-2 ----------------UGUAAACAUCCUUGACUGGAg------------------------------------------------------- 112 0,-2 ----------------UGUAAACAUCCUUGACUGGAu------------------------------------------------------- 197 0,-2 ----------------UGUAAACAUCCUUGACUGGAuu------------------------------------------------------ 6 0,-2 ----------------UGUAAACAUCCUUGACUGGAA------------------------------------------------------- 14769 0,-1 ----------------UGUAAACAUCCUUGACUGGAAa------------------------------------------------------ 5847 0,-1 ----------------UGUAAACAUCCUUGACUGGAAaa----------------------------------------------------- 383 0,-1 ----------------UGUAAACAUCCUUGACUGGAAau----------------------------------------------------- 52 0,-1 ----------------UGUAAACAUCCUUGACUGGAAc------------------------------------------------------ 39 0,-1 ----------------UGUAAACAUCCUUGACUGGAAu------------------------------------------------------ 563 0,-1 ----------------UGUAAACAUCCUUGACUGGAAuu----------------------------------------------------- 8 0,-1 ----------------UGUAAACAUCCUUGACUGGAAG------------------------------------------------------ 27779 0,0 ----------------UGUAAACAUCCUUGACUGGAAGa----------------------------------------------------- 3748 0,0 ----------------UGUAAACAUCCUUGACUGGAAGaa---------------------------------------------------- 85 0,0 ----------------UGUAAACAUCCUUGACUGGAAGau---------------------------------------------------- 367 0,0 ----------------UGUAAACAUCCUUGACUGGAAGg----------------------------------------------------- 50 0,0 ----------------UGUAAACAUCCUUGACUGGAAGu----------------------------------------------------- 2149 0,0 ----------------UGUAAACAUCCUUGACUGGAAGuu---------------------------------------------------- 224 0,0 ----------------UGUAAACAUCCUUGACUGGAAGC----------------------------------------------------- 27143 0,1 ----------------UGUAAACAUCCUUGACUGGAAGCa---------------------------------------------------- 1165 0,1 ----------------UGUAAACAUCCUUGACUGGAAGCaa--------------------------------------------------- 7 0,1 ----------------UGUAAACAUCCUUGACUGGAAGCau--------------------------------------------------- 6 0,1 ----------------UGUAAACAUCCUUGACUGGAAGCc---------------------------------------------------- 199 0,1 ----------------UGUAAACAUCCUUGACUGGAAGCg---------------------------------------------------- 123 0,1 ----------------UGUAAACAUCCUUGACUGGAAGCU---------------------------------------------------- 65685 0,2 ----------------UGUAAACAUCCUUGACUGGAAGCUa--------------------------------------------------- 126 0,2 ----------------UGUAAACAUCCUUGACUGGAAGCUu--------------------------------------------------- 1914 0,2 ----------------UGUAAACAUCCUUGACUGGAAGCUG--------------------------------------------------- 6 0,3 -----------------GUAAACAUCCUUGACUGG--------------------------------------------------------- 74 1,-3 -----------------GUAAACAUCCUUGACUGGA-------------------------------------------------------- 559 1,-2 -----------------GUAAACAUCCUUGACUGGAu------------------------------------------------------- 2 1,-2 -----------------GUAAACAUCCUUGACUGGAA------------------------------------------------------- 522 1,-1 -----------------GUAAACAUCCUUGACUGGAAa------------------------------------------------------ 248 1,-1 -----------------GUAAACAUCCUUGACUGGAAaa----------------------------------------------------- 7 1,-1 -----------------GUAAACAUCCUUGACUGGAAu------------------------------------------------------ 6 1,-1 -----------------GUAAACAUCCUUGACUGGAAG------------------------------------------------------ 1331 1,0 -----------------GUAAACAUCCUUGACUGGAAGa----------------------------------------------------- 185 1,0 -----------------GUAAACAUCCUUGACUGGAAGaa---------------------------------------------------- 6 1,0 -----------------GUAAACAUCCUUGACUGGAAGau---------------------------------------------------- 33 1,0 -----------------GUAAACAUCCUUGACUGGAAGu----------------------------------------------------- 63 1,0 -----------------GUAAACAUCCUUGACUGGAAGuu---------------------------------------------------- 4 1,0 -----------------GUAAACAUCCUUGACUGGAAGC----------------------------------------------------- 1661 1,1 -----------------GUAAACAUCCUUGACUGGAAGCa---------------------------------------------------- 86 1,1 -----------------GUAAACAUCCUUGACUGGAAGCc---------------------------------------------------- 21 1,1 -----------------GUAAACAUCCUUGACUGGAAGCU---------------------------------------------------- 7953 1,2 -----------------GUAAACAUCCUUGACUGGAAGCUa--------------------------------------------------- 29 1,2 -----------------GUAAACAUCCUUGACUGGAAGCUu--------------------------------------------------- 384 1,2 -----------------GUAAACAUCCUUGACUGGAAGCUuu-------------------------------------------------- 10 1,2 -----------------GUAAACAUCCUUGACUGGAAGCUG--------------------------------------------------- 129 1,3 -----------------GUAAACAUCCUUGACUGGAAGCUGa-------------------------------------------------- 6 1,3 -----------------GUAAACAUCCUUGACUGGAAGCUGU-------------------------------------------------- 126 1,4 ------------------UAAACAUCCUUGACUGGA-------------------------------------------------------- 3 2,-2 ------------------UAAACAUCCUUGACUGGAAGC----------------------------------------------------- 13 2,1 ------------------UAAACAUCCUUGACUGGAAGCU---------------------------------------------------- 110 2,2 ------------------UAAACAUCCUUGACUGGAAGCUG--------------------------------------------------- 15 2,3 ------------------UAAACAUCCUUGACUGGAAGCUGU-------------------------------------------------- 4 2,4 ---------------------------------------------------------GCUUUCAGUCGGAUGUUUACA-------------- 4 -1,-2 ---------------------------------------------------------GCUUUCAGUCGGAUGUUUACAG------------- 2 -1,-1 ---------------------------------------------------------GCUUUCAGUCGGAUGUUUACAGu------------ 4 -1,-1 ----------------------------------------------------------CUUUCAGUCGGAUGUUUA---------------- 70 0,-4 ----------------------------------------------------------CUUUCAGUCGGAUGUUUAa--------------- 25 0,-4 ----------------------------------------------------------CUUUCAGUCGGAUGUUUAaa-------------- 15 0,-4 ----------------------------------------------------------CUUUCAGUCGGAUGUUUAu--------------- 3 0,-4 ----------------------------------------------------------CUUUCAGUCGGAUGUUUAC--------------- 296 0,-3 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACc-------------- 2 0,-3 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACA-------------- 2463 0,-2 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAa------------- 128 0,-2 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAaa------------ 8 0,-2 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAau------------ 9 0,-2 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAu------------- 18 0,-2 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAuu------------ 39 0,-2 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAG------------- 2596 0,-1 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGa------------ 560 0,-1 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGaa----------- 12 0,-1 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGau----------- 2 0,-1 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGg------------ 2 0,-1 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGu------------ 8556 0,-1 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGuu----------- 667 0,-1 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGC------------ 3695 0,0 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGCa----------- 226 0,0 ----------------------------------------------------------CUUUCAGUCGGAUGUUUACAGCu----------- 80 0,0 -----------------------------------------------------------UUUCAGUCGGAUGUUUACA-------------- 47 1,-2 -----------------------------------------------------------UUUCAGUCGGAUGUUUACAa------------- 2 1,-2 -----------------------------------------------------------UUUCAGUCGGAUGUUUACAG------------- 70 1,-1 -----------------------------------------------------------UUUCAGUCGGAUGUUUACAGa------------ 10 1,-1 -----------------------------------------------------------UUUCAGUCGGAUGUUUACAGu------------ 250 1,-1 -----------------------------------------------------------UUUCAGUCGGAUGUUUACAGuu----------- 43 1,-1 -----------------------------------------------------------UUUCAGUCGGAUGUUUACAGC------------ 133 1,0 -----------------------------------------------------------UUUCAGUCGGAUGUUUACAGCa----------- 2 1,0 -----------------------------------------------------------UUUCAGUCGGAUGUUUACAGCu----------- 12 1,0 ------------------------------------------------------------UUCAGUCGGAUGUUUACAGC------------ 2 2,0 >hsa-mir-31 MA:8-28;mi:44-65 Tumor ggagaggAGGCAAGAUGCUGGCAUAGCUguugaacugggaaccUGCUAUGCCAACAUAUUGCCAUcuuucc -------AGGCAAGAUGCUGGCAUA---------------------------------------------- 2 0,-3 -------AGGCAAGAUGCUGGCAUAG--------------------------------------------- 15 0,-2 -------AGGCAAGAUGCUGGCAUAGa-------------------------------------------- 4 0,-2 -------AGGCAAGAUGCUGGCAUAGC-------------------------------------------- 10 0,-1 -------AGGCAAGAUGCUGGCAUAGCa------------------------------------------- 2 0,-1 -------AGGCAAGAUGCUGGCAUAGCU------------------------------------------- 149 0,0 -------AGGCAAGAUGCUGGCAUAGCUa------------------------------------------ 6 0,0 -------AGGCAAGAUGCUGGCAUAGCUau----------------------------------------- 4 0,0 -------AGGCAAGAUGCUGGCAUAGCUu------------------------------------------ 2 0,0 -------AGGCAAGAUGCUGGCAUAGCUG------------------------------------------ 262 0,1 -------AGGCAAGAUGCUGGCAUAGCUGa----------------------------------------- 38 0,1 -------AGGCAAGAUGCUGGCAUAGCUGU----------------------------------------- 258 0,2 -------AGGCAAGAUGCUGGCAUAGCUGUU---------------------------------------- 3 0,3 --------GGCAAGAUGCUGGCAUAGCUGU----------------------------------------- 2 1,2 -------------------------------------------UGCUAUGCCAACAUAUUG---------- 8 0,-4 -------------------------------------------UGCUAUGCCAACAUAUUGa--------- 5 0,-4 -------------------------------------------UGCUAUGCCAACAUAUUGC--------- 2 0,-3 -------------------------------------------UGCUAUGCCAACAUAUUGCC-------- 39 0,-2 -------------------------------------------UGCUAUGCCAACAUAUUGCCA------- 33 0,-1 -------------------------------------------UGCUAUGCCAACAUAUUGCCAU------ 35 0,0 -------------------------------------------UGCUAUGCCAACAUAUUGCCAUC----- 155 0,1 -------------------------------------------UGCUAUGCCAACAUAUUGCCAUCU---- 3 0,2 --------------------------------------------GCUAUGCCAACAUAUUGCCAUC----- 3 1,1 >hsa-mir-3115 5pM:6-25 Tumor ucugaAUAUGGGUUUACUAGUUGGUggugaauucaugagucgccaacuauuaggccuuuauguccaga -----AUAUGGGUUUACUAGUUGGU------------------------------------------- 2 0,0 >hsa-mir-3117 5p:13-32;3p:46-66 Tumor cccuaaagggccAGACACUAUACGAGUCAUAUaagggaaggcauuAUAGGACUCAUAUAGUGCCAGguguuuuguggg ---------------------------------------------AUAGGACUCAUAUAGUGCCA------------- 8 0,-1 ---------------------------------------------AUAGGACUCAUAUAGUGCCAG------------ 9 0,0 ---------------------------------------------AUAGGACUCAUAUAGUGCCAGa----------- 2 0,0 ---------------------------------------------AUAGGACUCAUAUAGUGCCAGu----------- 57 0,0 ---------------------------------------------AUAGGACUCAUAUAGUGCCAGuu---------- 2 0,0 ---------------------------------------------AUAGGACUCAUAUAGUGCCAGG----------- 20 0,1 ---------------------------------------------AUAGGACUCAUAUAGUGCCAGGa---------- 7 0,1 ----------------------------------------------UAGGACUCAUAUAGUGCCAGGU---------- 4 1,2 >hsa-mir-3126 5p:10-31;3p:46-67 Tumor augauuauaUGAGGGACAGAUGCCAGAAGCAcugguuaugauuugCAUCUGGCAUCCGUCACACAGAuaauuau ---------------------------------------------CAUCUGGCAUCCGUCACACAGA------- 3 0,0 >hsa-mir-3127 5p:11-33;3p:47-68 Tumor ggccaggcccAUCAGGGCUUGUGGAAUGGGAAGgagaagggacgcuUCCCCUUCUGCAGGCCUGCUGGguguggcu ----------AUCAGGGCUUGUGGAAUGGGAA-------------------------------------------- 2 0,-1 ----------AUCAGGGCUUGUGGAAUGGGAAu------------------------------------------- 2 0,-1 >hsa-mir-3129 5p:9-30;3p:47-68 Tumor guacuuggGCAGUAGUGUAGAGAUUGGUUUgccuguuaaugaauucAAACUAAUCUCUACACUGCUGCccaagagc ----------------------------------------------AAACUAAUCUCUACACUGCUGC-------- 12 0,0 -----------------------------------------------AACUAAUCUCUACACUGCUGCC------- 3 1,1 >hsa-mir-3130-1 5p:13-33;3p:44-64 Tumor cuugucaugucuUACCCAGUCUCCGGUGCAGCCuguugucaagGCUGCACCGGAGACUGGGUAAgacaugacaag ------------UACCCAGUCUCCGGUGCAGCC------------------------------------------ 2 0,0 ------------UACCCAGUCUCCGGUGCAGCCU----------------------------------------- 2 0,1 -------------------------------------------GCUGCACCGGAGACUGGGUAAG---------- 4 0,1 >hsa-mir-3130-2 5p:13-33;3p:44-64 Tumor cuugucaugucuUACCCAGUCUCCGGUGCAGCCuugacaacagGCUGCACCGGAGACUGGGUAAgacaugacaag ------------UACCCAGUCUCCGGUGCAGCC------------------------------------------ 2 0,0 ------------UACCCAGUCUCCGGUGCAGCCU----------------------------------------- 2 0,1 -------------------------------------------GCUGCACCGGAGACUGGGUAAG---------- 4 0,1 >hsa-mir-3133 5pM:10-31 Tumor cagaaauugUAAAGAACUCUUAAAACCCAAUaguaaaaagacaaccuguugaguuuuaagaguucuuuauauauucug ---------UAAAGAACUCUUAAAACCCAAU----------------------------------------------- 2 0,0 ----------AAAGAACUCUUAAAACCCAAU----------------------------------------------- 2 1,0 ------------------------------------------------UUGAGUUUUAAGAGUUCUUUAU-------- 3 >hsa-mir-3134 3pM:45-67 Tumor uguauccaauguguagucuuuuaucccucacauggaguaaaauaUGAUGGAUAAAAGACUACAUAUUggguaca --------------------------------------------UGAUGGAUAAAAGACUACAUAU-------- 2 0,-1 --------------------------------------------UGAUGGAUAAAAGACUACAUAUU------- 2 0,0 >hsa-mir-3136 5p:10-32;3p:49-70 Tumor aauaugaaaCUGACUGAAUAGGUAGGGUCAUUuuucugugacugcacaUGGCCCAACCUAUUCAGUUAGUuccauauu ---------CUGACUGAAUAGGUAGGGUCA------------------------------------------------ 2 0,-2 ---------CUGACUGAAUAGGUAGGGUCAU----------------------------------------------- 12 0,-1 ---------CUGACUGAAUAGGUAGGGUCAUU---------------------------------------------- 2 0,0 >hsa-mir-3140 5p:12-32;3p:60-81 Tumor ccucuugagguACCUGAAUUACCAAAAGCUUUauguauucugaaguuauugaaaauaagAGCUUUUGGGAAUUCAGGUAGUucaggagug -----------------------------------------------------------AGCUUUUGGGAAUUCAGGUAGU--------- 2 0,0 >hsa-mir-3145 5p:12-33;3p:49-72 Tumor uauaugaguucAACUCCAAACACUCAAAACUCAuuguugaauggaaugAGAUAUUUUGAGUGUUUGGAAUUGaacucguaua -----------AACUCCAAACACUCAAAACUC-------------------------------------------------- 2 0,-1 ------------------------------------------------AGAUAUUUUGAGUGUUUGGAAU------------ 3 0,-2 >hsa-mir-3150a 5p:12-33;3p:49-70 Tumor gggaagcaggcCAACCUCGACGAUCUCCUCAGCaccugaacgccaaggCUGGGGAGAUCCUCGAGGUUGGccugcuuucc ------------AACCUCGACGAUCUCCUCAGC----------------------------------------------- 2 1,0 ------------------------------------------------CUGGGGAGAUCCUCGAGGUUGG---------- 2 0,0 >hsa-mir-3150b 5p:15-36;3p:53-73 Tumor gagggaaagcaggcCAACCUCGAGGAUCUCCCCAGCcuuggcguucaggugcUGAGGAGAUCGUCGAGGUUGGccugcuuccccuc ---------------AACCUCGAGGAUCUCCCCAGu-------------------------------------------------- 2 1,-1 ----------------------------------------------------UGAGGAGAUCGUCGAGGUUG-------------- 4 0,-1 >hsa-mir-3156-1 5p:8-29;3p:49-69 Tumor gcagaagAAAGAUCUGGAAGUGGGAGACAcuuuuacuauauauaguggCUCCCACUUCCAGAUCUUUCUcucugu -------AAAGAUCUGGAAGUGGGAGA------------------------------------------------ 3 0,-2 -------AAAGAUCUGGAAGUGGGAGAC----------------------------------------------- 9 0,-1 -------AAAGAUCUGGAAGUGGGAGACA---------------------------------------------- 2 0,0 ------------------------------------------------CUCCCACUUCCAGAUCUUUC------- 2 0,-1 ------------------------------------------------CUCCCACUUCCAGAUCUUUCUCU---- 2 0,2 >hsa-mir-3156-2 5p:9-30;3p:50-70 Tumor ugcagaagAAAGAUCUGGAAGUGGGAGACAcuuucacuauauauaguggCUCCCACUUCCAGAUCUUUCUcucugua --------AAAGAUCUGGAAGUGGGAGA------------------------------------------------- 3 0,-2 --------AAAGAUCUGGAAGUGGGAGAC------------------------------------------------ 9 0,-1 --------AAAGAUCUGGAAGUGGGAGACA----------------------------------------------- 2 0,0 -------------------------------------------------CUCCCACUUCCAGAUCUUUC-------- 2 0,-1 -------------------------------------------------CUCCCACUUCCAGAUCUUUCUCU----- 2 0,2 >hsa-mir-3156-3 5pM:9-30 Tumor ugcagaagAAAGAUCUGGAAGUGGGAGACAcuuucacuauauauaguggcucccacuuccugaucuuucucucugua --------AAAGAUCUGGAAGUGGGAGA------------------------------------------------- 3 0,-2 --------AAAGAUCUGGAAGUGGGAGAC------------------------------------------------ 9 0,-1 --------AAAGAUCUGGAAGUGGGAGACA----------------------------------------------- 2 0,0 >hsa-mir-3157 5p:10-31;3p:58-79 Tumor gggaagggcUUCAGCCAGGCUAGUGCAGUCUgcuuugugccaacacuggggugaugaCUGCCCUAGUCUAGCUGAAGCUuuuccc ---------UUCAGCCAGGCUAGUGCAG--------------------------------------------------------- 2 0,-3 ---------UUCAGCCAGGCUAGUGCAGUC------------------------------------------------------- 2 0,-1 ---------UUCAGCCAGGCUAGUGCAGUCU------------------------------------------------------ 2 0,0 >hsa-mir-3158-1 5p:13-33;3p:50-71 Tumor auucaggccgguCCUGCAGAGAGGAAGCCCUUCugcuuacagguauuggAAGGGCUUCCUCUCUGCAGGACcggccugaau ------------CCUGCAGAGAGGAAGCCCUUCU----------------------------------------------- 2 0,1 -------------------------------------------------AAGGGCUUCCUCUCUGCAGGA----------- 27 0,-1 -------------------------------------------------AAGGGCUUCCUCUCUGCAGGAaa--------- 2 0,-1 -------------------------------------------------AAGGGCUUCCUCUCUGCAGGAu---------- 2 0,-1 -------------------------------------------------AAGGGCUUCCUCUCUGCAGGAC---------- 18 0,0 --------------------------------------------------AGGGCUUCCUCUCUGCAGGAC---------- 2 1,0 >hsa-mir-3158-2 3pM:50-71 Tumor auucaggccgguccugcagagaggaagcccuuccaauaccuguaagcagAAGGGCUUCCUCUCUGCAGGACcggccugaau -------------------------------------------------AAGGGCUUCCUCUCUGCAGGA----------- 27 0,-1 -------------------------------------------------AAGGGCUUCCUCUCUGCAGGAaa--------- 2 0,-1 -------------------------------------------------AAGGGCUUCCUCUCUGCAGGAu---------- 2 0,-1 -------------------------------------------------AAGGGCUUCCUCUCUGCAGGAC---------- 18 0,0 --------------------------------------------------AGGGCUUCCUCUCUGCAGGAC---------- 2 1,0 >hsa-mir-3159 5pM:10-31 Tumor ccaaaguccUAGGAUUACAAGUGUCGGCCACgggcugggcacaguggcucacgccuguaaucccagcauuuugg -------------------------------------------GUGGCUCACGCCUGUAAUC------------ 2 -------------------------------------------GUGGCUCACGCCUGUAAUCCC---------- 4 -------------------------------------------GUGGCUCACGCCUGUAAUCCCAGC------- 2 -------------------------------------------GUGGCUCACGCCUGUAAUCCCAGCA------ 2 --------------------------------------------UGGCUCACGCCUGUAAUCC----------- 2 --------------------------------------------UGGCUCACGCCUGUAAUCCC---------- 3 --------------------------------------------UGGCUCACGCCUGUAAUCCCAG-------- 2 --------------------------------------------UGGCUCACGCCUGUAAUCCCAGC------- 2 ----------------------------------------------GCUCACGCCUGUAAUCCCAGC------- 4 ----------------------------------------------GCUCACGCCUGUAAUCCCAGCA------ 2 -----------------------------------------------CUCACGCCUGUAAUCCCAGC------- 11 -----------------------------------------------CUCACGCCUGUAAUCCCAGCA------ 3 -----------------------------------------------CUCACGCCUGUAAUCCCAGCAc----- 5 ------------------------------------------------UCACGCCUGUAAUCCCAGCA------ 2 --------------------------------------------------ACGCCUGUAAUCCCAGCA------ 4 >hsa-mir-3171 5pM:10-33 Tumor uauauauagAGAUGUAUGGAAUCUGUAUAUAUCuauauauauguguauauauagauuccauaaaucuauauaug -----------------------------------------------UAUAUAGAUUCCAUAAAUCUAU----- 2 >hsa-mir-3173 5p:5-26;3p:43-64 Tumor ucccUGCCCUGCCUGUUUUCUCCUUUgugauuuuaugagaacAAAGGAGGAAAUAGGCAGGCCAggga ----UGCCCUGCCUGUUUUCUCCUU------------------------------------------- 2 0,-1 ----UGCCCUGCCUGUUUUCUCCUUU------------------------------------------ 5 0,0 ------CCCUGCCUGUUUUCUCCUUUGU---------------------------------------- 2 2,2 >hsa-mir-3174 5pM:10-32 Tumor guuaccuggUAGUGAGUUAGAGAUGCAGAGCCcugggcuccucagcaaaccuacuggaucugcauuuuaauucacaugcaugguaau ---------UAGUGAGUUAGAGAUGCAGAGC-------------------------------------------------------- 10 0,-1 >hsa-mir-3176 3pM:60-78 Tumor uggccucuccagucugcagcucccggcagccucgggccacacucccgggauccccagggACUGGCCUGGGACUACCGGggguggcggccg -----------------------------------------------------------ACUGGCCUGGGACUACCGGGG---------- 12 0,2 -----------------------------------------------------------ACUGGCCUGGGACUACCGGGGa--------- 4 0,2 -----------------------------------------------------------ACUGGCCUGGGACUACCGGGGG--------- 5 0,3 -----------------------------------------------------------ACUGGCCUGGGACUACCGGGGGa-------- 2 0,3 -----------------------------------------------------------ACUGGCCUGGGACUACCGGGGGg-------- 2 0,3 -----------------------------------------------------------ACUGGCCUGGGACUACCGGGGGU-------- 2 0,4 >hsa-mir-3177 5p:11-33;3p:54-74 Tumor ccacgugccaUGUGUACACACGUGCCAGGCGCUgucuugagacauucgcgcagUGCACGGCACUGGGGACACGUggcacugg -----------------------------------------------------UGCACGGCACUGGGGACACGU-------- 11 0,0 -----------------------------------------------------UGCACGGCACUGGGGACACGUu------- 2 0,0 >hsa-mir-3179-1 3pM:52-73 Tumor caggaucacagacguuuaaauuacacuccuucugcugugccuuacagcaguAGAAGGGGUGAAAUUUAAACGUcugugauccug --------------------------------------------------UAGAAGGGGUGAAAUUUAAACGU----------- 2 -1,0 >hsa-mir-3179-2 3pM:52-73 Tumor caggaucacagacguuuaaauuacacuccuucugcugugccuuacagcaguAGAAGGGGUGAAAUUUAAACGUcugugauccug --------------------------------------------------UAGAAGGGGUGAAAUUUAAACGU----------- 2 -1,0 >hsa-mir-3179-3 3pM:52-73 Tumor caggaucacagacguuuaaauuacacuccuucugcugugccuuacagcaguAGAAGGGGUGAAAUUUAAACGUcugugauccug --------------------------------------------------UAGAAGGGGUGAAAUUUAAACGU----------- 2 -1,0 >hsa-mir-3180-1 5p:18-42;3p:62-83 Tumor cagugcgacgggcggagCUUCCAGACGCUCCGCCCCACGUCGcaugcgccccgggaaagcgUGGGGCGGAGCUUCCGGAGGCCccgcccugcug -----------------CUUCCAGACGCUCCGCCCCACG------------------------------------------------------- 2 0,-3 -------------------------------------------------------------UGGGGCGGAGCUUCCGGA--------------- 2 0,-4 -------------------------------------------------------------UGGGGCGGAGCUUCCGGAGGC------------ 2 0,-1 -------------------------------------------------------------UGGGGCGGAGCUUCCGGAGGCC----------- 4 0,0 >hsa-mir-3180-2 5p:14-38;3p:58-79 Tumor gcgacgggcggagCUUCCAGACGCUCCGCCCCACGUCGcaugcgccccgggaaagcgUGGGGCGGAGCUUCCGGAGGCCccgcccugc -------------CUUCCAGACGCUCCGCCCCACG----------------------------------------------------- 2 0,-3 ---------------------------------------------------------UGGGGCGGAGCUUCCGGA------------- 2 0,-4 ---------------------------------------------------------UGGGGCGGAGCUUCCGGAGGC---------- 2 0,-1 ---------------------------------------------------------UGGGGCGGAGCUUCCGGAGGCC--------- 4 0,0 >hsa-mir-3180-3 5p:18-42;3p:62-83 Tumor cagugcgacgggcggagCUUCCAGACGCUCCGCCCCACGUCGcaugcgccccgggaaagcgUGGGGCGGAGCUUCCGGAGGCCccgcccugcug -----------------CUUCCAGACGCUCCGCCCCACG------------------------------------------------------- 2 0,-3 -------------------------------------------------------------UGGGGCGGAGCUUCCGGA--------------- 2 0,-4 -------------------------------------------------------------UGGGGCGGAGCUUCCGGAGGC------------ 2 0,-1 -------------------------------------------------------------UGGGGCGGAGCUUCCGGAGGCC----------- 4 0,0 >hsa-mir-3180-4 5pM:36-54 Tumor gcuccgccccacgucgcaugcgccccgggaacgcgUGGGGCGGAGCUUCCGGAGgccccgcucugcugccgacccuguggagcggagggugaagccuccggaugccagucccucaucgcuggccuggucgcgcuguggcgaagggggcggagc -----------------------------------UGGGGCGGAGCUUCCGGA---------------------------------------------------------------------------------------------------- 2 0,-1 -----------------------------------UGGGGCGGAGCUUCCGGAGGC------------------------------------------------------------------------------------------------- 2 0,2 -----------------------------------UGGGGCGGAGCUUCCGGAGGCC------------------------------------------------------------------------------------------------ 4 0,3 >hsa-mir-3180-5 5pM:36-54 Tumor gcuccgccccacgucgcaugcgccccgggaacgcgUGGGGCGGAGCUUCCGGAGgccccgcccugcugccgacccuguggagcggagggugaagccuccggaugccagucccucaucgcuggcccggucgcgcuguggcgaagggggcggagc -----------------------------------UGGGGCGGAGCUUCCGGA---------------------------------------------------------------------------------------------------- 2 0,-1 -----------------------------------UGGGGCGGAGCUUCCGGAGGC------------------------------------------------------------------------------------------------- 2 0,2 -----------------------------------UGGGGCGGAGCUUCCGGAGGCC------------------------------------------------------------------------------------------------ 4 0,3 >hsa-mir-3187 5p:7-29;3p:44-63 Tumor gcuggcCCUGGGCAGCGUGUGGCUGAAGGucaccauguucuccUUGGCCAUGGGGCUGCGCGGggccagc -------------------------------------------UUGGCCAUGGGGCUGCGCGG------- 8 0,0 >hsa-mir-3188 3pM:53-75 Tumor ggcgccuccugcucugcugugccgccagggccuccccuagcgcgccuucuggAGAGGCUUUGUGCGGAUACGGGGcuggaggccu ----------------------------------------------------AGAGGCUUUGUGCGGAUACG------------- 2 0,-3 ----------------------------------------------------AGAGGCUUUGUGCGGAUACGG------------ 2 0,-2 ----------------------------------------------------AGAGGCUUUGUGCGGAUACGGG----------- 2 0,-1 >hsa-mir-3194 5p:10-30;3p:45-66 Tumor agguggcagGGCCAGCCACCAGGAGGGCUGcgugccacccgggcAGCUCUGCUGCUCACUGGCAGUgucaccu ---------GGCCAGCCACCAGGAGGGCU-------------------------------------------- 5 0,-1 ---------GGCCAGCCACCAGGAGGGCUG------------------------------------------- 2 0,0 ---------GGCCAGCCACCAGGAGGGCUGa------------------------------------------ 2 0,0 ---------GGCCAGCCACCAGGAGGGCUGu------------------------------------------ 2 0,0 ---------GGCCAGCCACCAGGAGGGCUGC------------------------------------------ 8 0,1 --------------------------------------------AGCUCUGCUGCUCACUGGCA--------- 2 0,-2 --------------------------------------------AGCUCUGCUGCUCACUGGCAGa------- 2 0,-1 --------------------------------------------AGCUCUGCUGCUCACUGGCAGU------- 2 0,0 --------------------------------------------AGCUCUGCUGCUCACUGGCAGUa------ 2 0,0 --------------------------------------------AGCUCUGCUGCUCACUGGCAGUaa----- 2 0,0 >hsa-mir-32 MA:6-27;mi:47-68 Tumor ggagaUAUUGCACAUUACUAAGUUGCAuguugucacggccucaaugCAAUUUAGUGUGUGUGAUAUUUuc ----AUAUUGCACAUUACUAAGUUG--------------------------------------------- 31 -1,-2 ----AUAUUGCACAUUACUAAGUUGa-------------------------------------------- 2 -1,-2 ----AUAUUGCACAUUACUAAGUUGC-------------------------------------------- 130 -1,-1 ----AUAUUGCACAUUACUAAGUUGCA------------------------------------------- 88 -1,0 -----UAUUGCACAUUACUAAGUU---------------------------------------------- 123 0,-3 -----UAUUGCACAUUACUAAGUUa--------------------------------------------- 5 0,-3 -----UAUUGCACAUUACUAAGUUu--------------------------------------------- 2 0,-3 -----UAUUGCACAUUACUAAGUUG--------------------------------------------- 1857 0,-2 -----UAUUGCACAUUACUAAGUUGa-------------------------------------------- 81 0,-2 -----UAUUGCACAUUACUAAGUUGaa------------------------------------------- 4 0,-2 -----UAUUGCACAUUACUAAGUUGu-------------------------------------------- 14 0,-2 -----UAUUGCACAUUACUAAGUUGC-------------------------------------------- 4971 0,-1 -----UAUUGCACAUUACUAAGUUGCc------------------------------------------- 32 0,-1 -----UAUUGCACAUUACUAAGUUGCu------------------------------------------- 2 0,-1 -----UAUUGCACAUUACUAAGUUGCA------------------------------------------- 4227 0,0 -----UAUUGCACAUUACUAAGUUGCAa------------------------------------------ 323 0,0 -----UAUUGCACAUUACUAAGUUGCAU------------------------------------------ 150 0,1 -----UAUUGCACAUUACUAAGUUGCAUu----------------------------------------- 14 0,1 ------AUUGCACAUUACUAAGUUG--------------------------------------------- 31 1,-2 ------AUUGCACAUUACUAAGUUGC-------------------------------------------- 151 1,-1 ------AUUGCACAUUACUAAGUUGCA------------------------------------------- 102 1,0 ------AUUGCACAUUACUAAGUUGCAa------------------------------------------ 8 1,0 ------AUUGCACAUUACUAAGUUGCAU------------------------------------------ 4 1,1 --------------------------------------------UGCAAUUUAGUGUGUGUGAU------ 2 -2,-4 --------------------------------------------UGCAAUUUAGUGUGUGUGAUAU---- 2 -2,-2 ---------------------------------------------GCAAUUUAGUGUGUGUGAUAUU--- 17 -1,-1 ----------------------------------------------CAAUUUAGUGUGUGUGAUA----- 4 0,-3 ----------------------------------------------CAAUUUAGUGUGUGUGAUAU---- 8 0,-2 ----------------------------------------------CAAUUUAGUGUGUGUGAUAUU--- 267 0,-1 ----------------------------------------------CAAUUUAGUGUGUGUGAUAUUU-- 5 0,0 -----------------------------------------------AAUUUAGUGUGUGUGAUAUU--- 2 1,-1 ------------------------------------------------AUUUAGUGUGUGUGAUAUU--- 3 2,-1 >hsa-mir-3200 5p:13-34;3p:54-75 Tumor gguggucgagggAAUCUGAGAAGGCGCACAAGGUuuguguccaauacaguccaCACCUUGCGCUACUCAGGUCUGcucgugcccu -----------------------------------------------------CACCUUGCGCUACUCAGGUC------------ 8 0,-2 -----------------------------------------------------CACCUUGCGCUACUCAGGUCU----------- 57 0,-1 -----------------------------------------------------CACCUUGCGCUACUCAGGUCUG---------- 71 0,0 -----------------------------------------------------CACCUUGCGCUACUCAGGUCUGa--------- 26 0,0 -----------------------------------------------------CACCUUGCGCUACUCAGGUCUGu--------- 83 0,0 -----------------------------------------------------CACCUUGCGCUACUCAGGUCUGuu-------- 2 0,0 -----------------------------------------------------CACCUUGCGCUACUCAGGUCUGC--------- 110 0,1 -----------------------------------------------------CACCUUGCGCUACUCAGGUCUGCa-------- 5 0,1 -----------------------------------------------------CACCUUGCGCUACUCAGGUCUGCU-------- 2 0,2 ------------------------------------------------------ACCUUGCGCUACUCAGGUCUG---------- 2 1,0 ------------------------------------------------------ACCUUGCGCUACUCAGGUCUGC--------- 2 1,1 >hsa-mir-320a 3pM:48-69 Tumor gcuucgcuccccuccgccuucucuucccgguucuucccggagucgggAAAAGCUGGGUUGAGAGGGCGAaaaaggaugaggu ---------------GCCUUCUCUUCCCGGUUCUUCCCG------------------------------------------- 2 ----------------------------------------------GAAAAGCUGGGUUGAGAG------------------ 8 -1,-5 ----------------------------------------------GAAAAGCUGGGUUGAGAGa----------------- 6 -1,-5 ----------------------------------------------GAAAAGCUGGGUUGAGAGG----------------- 19 -1,-4 ----------------------------------------------GAAAAGCUGGGUUGAGAGGG---------------- 13 -1,-3 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGa--------------- 2 -1,-3 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGC--------------- 41 -1,-2 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGCu-------------- 7 -1,-2 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGCG-------------- 193 -1,-1 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGCGu------------- 104 -1,-1 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGCGA------------- 394 -1,0 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGCGAu------------ 6 -1,0 ----------------------------------------------GAAAAGCUGGGUUGAGAGGGCGAA------------ 2 -1,1 -----------------------------------------------AAAAGCUGGGUUGAGAGG----------------- 1162 0,-4 -----------------------------------------------AAAAGCUGGGUUGAGAGGu---------------- 50 0,-4 -----------------------------------------------AAAAGCUGGGUUGAGAGGuu--------------- 12 0,-4 -----------------------------------------------AAAAGCUGGGUUGAGAGGG---------------- 1092 0,-3 -----------------------------------------------AAAAGCUGGGUUGAGAGGGa--------------- 405 0,-3 -----------------------------------------------AAAAGCUGGGUUGAGAGGGaa-------------- 186 0,-3 -----------------------------------------------AAAAGCUGGGUUGAGAGGGau-------------- 62 0,-3 -----------------------------------------------AAAAGCUGGGUUGAGAGGGC--------------- 2059 0,-2 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCc-------------- 2 0,-2 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCu-------------- 127 0,-2 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCuu------------- 71 0,-2 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCG-------------- 7470 0,-1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGc------------- 300 0,-1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGg------------- 33 0,-1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGu------------- 4251 0,-1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGuu------------ 1559 0,-1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGA------------- 42596 0,0 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAc------------ 151 0,0 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAg------------ 282 0,0 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAu------------ 12453 0,0 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAuu----------- 3143 0,0 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAA------------ 15622 0,1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAc----------- 83 0,1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAg----------- 377 0,1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAu----------- 7398 0,1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAuu---------- 298 0,1 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAA----------- 4957 0,2 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAAc---------- 4 0,2 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAAg---------- 6 0,2 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAAu---------- 654 0,2 -----------------------------------------------AAAAGCUGGGUUGAGAGGGCGAAAA---------- 360 0,3 ------------------------------------------------AAAGCUGGGUUGAGAGGG---------------- 32 1,-3 ------------------------------------------------AAAGCUGGGUUGAGAGGGa--------------- 10 1,-3 ------------------------------------------------AAAGCUGGGUUGAGAGGGaa-------------- 15 1,-3 ------------------------------------------------AAAGCUGGGUUGAGAGGGau-------------- 4 1,-3 ------------------------------------------------AAAGCUGGGUUGAGAGGGC--------------- 64 1,-2 ------------------------------------------------AAAGCUGGGUUGAGAGGGCG-------------- 439 1,-1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGu------------- 221 1,-1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGuu------------ 85 1,-1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGA------------- 2695 1,0 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAc------------ 5 1,0 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAg------------ 2 1,0 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAu------------ 768 1,0 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAuu----------- 283 1,0 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAA------------ 1415 1,1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAc----------- 2 1,1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAg----------- 23 1,1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAu----------- 962 1,1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAuu---------- 48 1,1 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAA----------- 720 1,2 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAAg---------- 4 1,2 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAAu---------- 135 1,2 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAAA---------- 56 1,3 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAAAu--------- 4 1,3 ------------------------------------------------AAAGCUGGGUUGAGAGGGCGAAAAA--------- 2 1,4 -------------------------------------------------AAGCUGGGUUGAGAGGGC--------------- 2 2,-2 -------------------------------------------------AAGCUGGGUUGAGAGGGCG-------------- 7 2,-1 -------------------------------------------------AAGCUGGGUUGAGAGGGCGu------------- 2 2,-1 -------------------------------------------------AAGCUGGGUUGAGAGGGCGA------------- 208 2,0 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAu------------ 73 2,0 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAuu----------- 34 2,0 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAA------------ 245 2,1 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAAg----------- 4 2,1 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAAu----------- 218 2,1 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAAuu---------- 13 2,1 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAAA----------- 320 2,2 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAAAu---------- 106 2,2 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAAAA---------- 53 2,3 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAAAAu--------- 11 2,3 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAAAAuu-------- 2 2,3 -------------------------------------------------AAGCUGGGUUGAGAGGGCGAAAAA--------- 3 2,4 >hsa-mir-320b-1 3pM:39-60 Tumor aauuaaucccucucuuucuaguucuuccuagagugaggAAAAGCUGGGUUGAGAGGGCAAacaaauuaacuaauuaauu -------------------------------------GAAAAGCUGGGUUGAGAG------------------------ 8 -1,-5 -------------------------------------GAAAAGCUGGGUUGAGAGa----------------------- 6 -1,-5 -------------------------------------GAAAAGCUGGGUUGAGAGG----------------------- 19 -1,-4 -------------------------------------GAAAAGCUGGGUUGAGAGGG---------------------- 13 -1,-3 -------------------------------------GAAAAGCUGGGUUGAGAGGGa--------------------- 2 -1,-3 -------------------------------------GAAAAGCUGGGUUGAGAGGGC--------------------- 41 -1,-2 -------------------------------------GAAAAGCUGGGUUGAGAGGGCu-------------------- 7 -1,-2 -------------------------------------GAAAAGCUGGGUUGAGAGGGCAu------------------- 2 -1,-1 --------------------------------------AAAAGCUGGGUUGAGAGG----------------------- 1162 0,-4 --------------------------------------AAAAGCUGGGUUGAGAGGu---------------------- 50 0,-4 --------------------------------------AAAAGCUGGGUUGAGAGGuu--------------------- 12 0,-4 --------------------------------------AAAAGCUGGGUUGAGAGGG---------------------- 1092 0,-3 --------------------------------------AAAAGCUGGGUUGAGAGGGa--------------------- 405 0,-3 --------------------------------------AAAAGCUGGGUUGAGAGGGaa-------------------- 186 0,-3 --------------------------------------AAAAGCUGGGUUGAGAGGGau-------------------- 62 0,-3 --------------------------------------AAAAGCUGGGUUGAGAGGGC--------------------- 2059 0,-2 --------------------------------------AAAAGCUGGGUUGAGAGGGCc-------------------- 2 0,-2 --------------------------------------AAAAGCUGGGUUGAGAGGGCu-------------------- 127 0,-2 --------------------------------------AAAAGCUGGGUUGAGAGGGCuu------------------- 71 0,-2 --------------------------------------AAAAGCUGGGUUGAGAGGGCA-------------------- 125 0,-1 --------------------------------------AAAAGCUGGGUUGAGAGGGCAg------------------- 2 0,-1 --------------------------------------AAAAGCUGGGUUGAGAGGGCAu------------------- 149 0,-1 --------------------------------------AAAAGCUGGGUUGAGAGGGCAuu------------------ 16 0,-1 --------------------------------------AAAAGCUGGGUUGAGAGGGCAA------------------- 298 0,0 --------------------------------------AAAAGCUGGGUUGAGAGGGCAAu------------------ 81 0,0 --------------------------------------AAAAGCUGGGUUGAGAGGGCAAuu----------------- 13 0,0 --------------------------------------AAAAGCUGGGUUGAGAGGGCAAA------------------ 79 0,1 --------------------------------------AAAAGCUGGGUUGAGAGGGCAAAg----------------- 2 0,1 --------------------------------------AAAAGCUGGGUUGAGAGGGCAAAu----------------- 7 0,1 ---------------------------------------AAAGCUGGGUUGAGAGGG---------------------- 32 1,-3 ---------------------------------------AAAGCUGGGUUGAGAGGGa--------------------- 10 1,-3 ---------------------------------------AAAGCUGGGUUGAGAGGGaa-------------------- 15 1,-3 ---------------------------------------AAAGCUGGGUUGAGAGGGau-------------------- 4 1,-3 ---------------------------------------AAAGCUGGGUUGAGAGGGC--------------------- 64 1,-2 ---------------------------------------AAAGCUGGGUUGAGAGGGCA-------------------- 5 1,-1 ---------------------------------------AAAGCUGGGUUGAGAGGGCAu------------------- 2 1,-1 ---------------------------------------AAAGCUGGGUUGAGAGGGCAA------------------- 6 1,0 ----------------------------------------AAGCUGGGUUGAGAGGGC--------------------- 2 2,-2 >hsa-mir-320b-2 3pM:72-93 Tumor uguuauuuuuugucuucuaccuaagaauucugucucuuaggcuuucucuucccagauuucccaaaguugggAAAAGCUGGGUUGAGAGGGCAAaaggaaaaaaaaagaauucugucucugacauaauuagauagggaa ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAG-------------------------------------------------- 8 -1,-5 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGa------------------------------------------------- 6 -1,-5 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGG------------------------------------------------- 19 -1,-4 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGGG------------------------------------------------ 13 -1,-3 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGGGa----------------------------------------------- 2 -1,-3 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGGGC----------------------------------------------- 41 -1,-2 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGGGCu---------------------------------------------- 7 -1,-2 ----------------------------------------------------------------------GAAAAGCUGGGUUGAGAGGGCAu--------------------------------------------- 2 -1,-1 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGG------------------------------------------------- 1162 0,-4 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGu------------------------------------------------ 50 0,-4 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGuu----------------------------------------------- 12 0,-4 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGG------------------------------------------------ 1092 0,-3 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGa----------------------------------------------- 405 0,-3 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGaa---------------------------------------------- 186 0,-3 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGau---------------------------------------------- 62 0,-3 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGC----------------------------------------------- 2059 0,-2 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCc---------------------------------------------- 2 0,-2 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCu---------------------------------------------- 127 0,-2 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCuu--------------------------------------------- 71 0,-2 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCA---------------------------------------------- 125 0,-1 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAg--------------------------------------------- 2 0,-1 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAu--------------------------------------------- 149 0,-1 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAuu-------------------------------------------- 16 0,-1 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAA--------------------------------------------- 298 0,0 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAAu-------------------------------------------- 81 0,0 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAAuu------------------------------------------- 13 0,0 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAAA-------------------------------------------- 79 0,1 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAAAg------------------------------------------- 2 0,1 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAAAu------------------------------------------- 7 0,1 -----------------------------------------------------------------------AAAAGCUGGGUUGAGAGGGCAAAA------------------------------------------- 17 0,2 ------------------------------------------------------------------------AAAGCUGGGUUGAGAGGG------------------------------------------------ 32 1,-3 ------------------------------------------------------------------------AAAGCUGGGUUGAGAGGGa----------------------------------------------- 10 1,-3 ------------------------------------------------------------------------AAAGCUGGGUUGAGAGGGaa---------------------------------------------- 15 1,-3 ------------------------------------------------------------------------AAAGCUGGGUUGAGAGGGau---------------------------------------------- 4 1,-3 ------------------------------------------------------------------------AAAGCUGGGUUGAGAGGGC----------------------------------------------- 64 1,-2 ------------------------------------------------------------------------AAAGCUGGGUUGAGAGGGCA---------------------------------------------- 5 1,-1 ------------------------------------------------------------------------AAAGCUGGGUUGAGAGGGCAu--------------------------------------------- 2 1,-1 ------------------------------------------------------------------------AAAGCUGGGUUGAGAGGGCAA--------------------------------------------- 6 1,0 -------------------------------------------------------------------------AAGCUGGGUUGAGAGGGC----------------------------------------------- 2 2,-2 >hsa-mir-320c-1 3pM:50-69 Tumor uuugcauuaaaaaugaggccuucucuucccaguucuucccagagucaggAAAAGCUGGGUUGAGAGGGUagaaaaaaaaugauguagg ------------------------------------------------GAAAAGCUGGGUUGAGAG---------------------- 8 -1,-3 ------------------------------------------------GAAAAGCUGGGUUGAGAGa--------------------- 6 -1,-3 ------------------------------------------------GAAAAGCUGGGUUGAGAGG--------------------- 19 -1,-2 ------------------------------------------------GAAAAGCUGGGUUGAGAGGG-------------------- 13 -1,-1 ------------------------------------------------GAAAAGCUGGGUUGAGAGGGa------------------- 2 -1,-1 -------------------------------------------------AAAAGCUGGGUUGAGAGG--------------------- 1162 0,-2 -------------------------------------------------AAAAGCUGGGUUGAGAGGu-------------------- 50 0,-2 -------------------------------------------------AAAAGCUGGGUUGAGAGGuu------------------- 12 0,-2 -------------------------------------------------AAAAGCUGGGUUGAGAGGG-------------------- 1092 0,-1 -------------------------------------------------AAAAGCUGGGUUGAGAGGGa------------------- 405 0,-1 -------------------------------------------------AAAAGCUGGGUUGAGAGGGaa------------------ 186 0,-1 -------------------------------------------------AAAAGCUGGGUUGAGAGGGau------------------ 62 0,-1 -------------------------------------------------AAAAGCUGGGUUGAGAGGGU------------------- 275 0,0 -------------------------------------------------AAAAGCUGGGUUGAGAGGGUg------------------ 2 0,0 -------------------------------------------------AAAAGCUGGGUUGAGAGGGUu------------------ 21 0,0 -------------------------------------------------AAAAGCUGGGUUGAGAGGGUuu----------------- 18 0,0 -------------------------------------------------AAAAGCUGGGUUGAGAGGGUA------------------ 2 0,1 -------------------------------------------------AAAAGCUGGGUUGAGAGGGUAa----------------- 13 0,1 -------------------------------------------------AAAAGCUGGGUUGAGAGGGUAu----------------- 7 0,1 --------------------------------------------------AAAGCUGGGUUGAGAGGG-------------------- 32 1,-1 --------------------------------------------------AAAGCUGGGUUGAGAGGGa------------------- 10 1,-1 --------------------------------------------------AAAGCUGGGUUGAGAGGGaa------------------ 15 1,-1 --------------------------------------------------AAAGCUGGGUUGAGAGGGau------------------ 4 1,-1 --------------------------------------------------AAAGCUGGGUUGAGAGGGU------------------- 6 1,0 >hsa-mir-320c-2 3pM:31-50 Tumor cuucucuuuccaguucuucccagaauugggAAAAGCUGGGUUGAGAGGGU -----------------------------GAAAAGCUGGGUUGAGAG--- 8 -1,-3 -----------------------------GAAAAGCUGGGUUGAGAGa-- 6 -1,-3 -----------------------------GAAAAGCUGGGUUGAGAGG-- 19 -1,-2 -----------------------------GAAAAGCUGGGUUGAGAGGG- 13 -1,-1 -----------------------------GAAAAGCUGGGUUGAGAGGGa 2 -1,-1 ------------------------------AAAAGCUGGGUUGAGAGG-- 1162 0,-2 ------------------------------AAAAGCUGGGUUGAGAGGu- 50 0,-2 ------------------------------AAAAGCUGGGUUGAGAGGuu 12 0,-2 ------------------------------AAAAGCUGGGUUGAGAGGG- 1092 0,-1 ------------------------------AAAAGCUGGGUUGAGAGGGa 405 0,-1 ------------------------------AAAAGCUGGGUUGAGAGGGaa 186 0,-1 ------------------------------AAAAGCUGGGUUGAGAGGGau 62 0,-1 ------------------------------AAAAGCUGGGUUGAGAGGGU 275 0,0 ------------------------------AAAAGCUGGGUUGAGAGGGUg 2 0,0 ------------------------------AAAAGCUGGGUUGAGAGGGUu 21 0,0 ------------------------------AAAAGCUGGGUUGAGAGGGUuu 18 0,0 -------------------------------AAAGCUGGGUUGAGAGGG- 32 1,-1 -------------------------------AAAGCUGGGUUGAGAGGGa 10 1,-1 -------------------------------AAAGCUGGGUUGAGAGGGaa 15 1,-1 -------------------------------AAAGCUGGGUUGAGAGGGau 4 1,-1 -------------------------------AAAGCUGGGUUGAGAGGGU 6 1,0 >hsa-mir-320d-1 3pM:30-48 Tumor uucucgucccaguucuucccaaaguugagAAAAGCUGGGUUGAGAGGA ----------------------------GAAAAGCUGGGUUGAGAG-- 8 -1,-2 ----------------------------GAAAAGCUGGGUUGAGAGa- 6 -1,-2 ----------------------------GAAAAGCUGGGUUGAGAGG- 19 -1,-1 -----------------------------AAAAGCUGGGUUGAGAGG- 1162 0,-1 -----------------------------AAAAGCUGGGUUGAGAGGu 50 0,-1 -----------------------------AAAAGCUGGGUUGAGAGGuu 12 0,-1 -----------------------------AAAAGCUGGGUUGAGAGGA 369 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAa 159 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAaa 142 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAau 61 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAu 44 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAuu 2 0,0 ------------------------------AAAGCUGGGUUGAGAGGA 12 1,0 ------------------------------AAAGCUGGGUUGAGAGGAa 9 1,0 ------------------------------AAAGCUGGGUUGAGAGGAaa 5 1,0 ------------------------------AAAGCUGGGUUGAGAGGAau 2 1,0 >hsa-mir-320d-2 3pM:30-48 Tumor uucucuucccaguucuucuuggagucaggAAAAGCUGGGUUGAGAGGA ----------------------------GAAAAGCUGGGUUGAGAG-- 8 -1,-2 ----------------------------GAAAAGCUGGGUUGAGAGa- 6 -1,-2 ----------------------------GAAAAGCUGGGUUGAGAGG- 19 -1,-1 -----------------------------AAAAGCUGGGUUGAGAGG- 1162 0,-1 -----------------------------AAAAGCUGGGUUGAGAGGu 50 0,-1 -----------------------------AAAAGCUGGGUUGAGAGGuu 12 0,-1 -----------------------------AAAAGCUGGGUUGAGAGGA 369 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAa 159 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAaa 142 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAau 61 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAu 44 0,0 -----------------------------AAAAGCUGGGUUGAGAGGAuu 2 0,0 ------------------------------AAAGCUGGGUUGAGAGGA 12 1,0 ------------------------------AAAGCUGGGUUGAGAGGAa 9 1,0 ------------------------------AAAGCUGGGUUGAGAGGAaa 5 1,0 ------------------------------AAAGCUGGGUUGAGAGGAau 2 1,0 >hsa-mir-320e 3pM:35-52 Tumor gccuucucuucccaguucuuccuggagucggggaAAAGCUGGGUUGAGAAGGu --------------------------------GAAAAGCUGGGUUGAGAA--- 2 -2,-2 ---------------------------------AAAAGCUGGGUUGAGAAG-- 10 -1,-1 ---------------------------------AAAAGCUGGGUUGAGAAGG- 138 -1,0 ----------------------------------AAAGCUGGGUUGAGAAGG- 2 0,0 >hsa-mir-323 5p:16-37;3p:51-71 Tumor uugguacuuggagagAGGUGGUCCGUGGCGCGUUCGCuuuauuuauggcgCACAUUACACGGUCGACCUCUuugcaguaucuaauc -------------------------------------------------GCACAUUACACGGUCGACCUCU--------------- 46 -1,0 --------------------------------------------------CACAUUACACGGUCGACCUC---------------- 2 0,-1 --------------------------------------------------CACAUUACACGGUCGACCUCU--------------- 54 0,0 >hsa-mir-323b 5p:15-37;3p:51-72 Tumor ugguacucggagggAGGUUGUCCGUGGUGAGUUCGCAuuauuuaaugaugCCCAAUACACGGUCGACCUCUUuucgguauca --------------AGGUUGUCCGUGGUGAGUUCGCA--------------------------------------------- 4 0,0 --------------------------------------------------CCCAAUACACGGUCGACCUCc----------- 2 0,-2 --------------------------------------------------CCCAAUACACGGUCGACCUCU----------- 17 0,-1 >hsa-mir-324 5p:16-38;3p:53-72 Tumor cugacuaugccucccCGCAUCCCCUAGGGCAUUGGUGUaaagcuggagacccACUGCCCCAGGUGCUGCUGGggguuguaguc --------------CCGCAUCCCCUAGGGCAUUGGUGU--------------------------------------------- 2 -1,0 ---------------CGCAUCCCCUAGGGCAUU-------------------------------------------------- 4 0,-5 ---------------CGCAUCCCCUAGGGCAUUG------------------------------------------------- 7 0,-4 ---------------CGCAUCCCCUAGGGCAUUGG------------------------------------------------ 78 0,-3 ---------------CGCAUCCCCUAGGGCAUUGGa----------------------------------------------- 5 0,-3 ---------------CGCAUCCCCUAGGGCAUUGGU----------------------------------------------- 645 0,-2 ---------------CGCAUCCCCUAGGGCAUUGGUa---------------------------------------------- 46 0,-2 ---------------CGCAUCCCCUAGGGCAUUGGUaa--------------------------------------------- 18 0,-2 ---------------CGCAUCCCCUAGGGCAUUGGUau--------------------------------------------- 6 0,-2 ---------------CGCAUCCCCUAGGGCAUUGGUu---------------------------------------------- 37 0,-2 ---------------CGCAUCCCCUAGGGCAUUGGUuu--------------------------------------------- 7 0,-2 ---------------CGCAUCCCCUAGGGCAUUGGUG---------------------------------------------- 978 0,-1 ---------------CGCAUCCCCUAGGGCAUUGGUGa--------------------------------------------- 404 0,-1 ---------------CGCAUCCCCUAGGGCAUUGGUGaa-------------------------------------------- 3 0,-1 ---------------CGCAUCCCCUAGGGCAUUGGUGau-------------------------------------------- 4 0,-1 ---------------CGCAUCCCCUAGGGCAUUGGUGc--------------------------------------------- 5 0,-1 ---------------CGCAUCCCCUAGGGCAUUGGUGg--------------------------------------------- 2 0,-1 ---------------CGCAUCCCCUAGGGCAUUGGUGU--------------------------------------------- 4752 0,0 ---------------CGCAUCCCCUAGGGCAUUGGUGUu-------------------------------------------- 108 0,0 ---------------CGCAUCCCCUAGGGCAUUGGUGUuu------------------------------------------- 8 0,0 ---------------CGCAUCCCCUAGGGCAUUGGUGUA-------------------------------------------- 33 0,1 ---------------CGCAUCCCCUAGGGCAUUGGUGUAA------------------------------------------- 4 0,2 ----------------GCAUCCCCUAGGGCAUUGG------------------------------------------------ 2 1,-3 ----------------GCAUCCCCUAGGGCAUUGGU----------------------------------------------- 6 1,-2 ----------------GCAUCCCCUAGGGCAUUGGUG---------------------------------------------- 20 1,-1 ----------------GCAUCCCCUAGGGCAUUGGUGa--------------------------------------------- 4 1,-1 ----------------GCAUCCCCUAGGGCAUUGGUGU--------------------------------------------- 158 1,0 --------------------------------------------------CCACUGCCCCAGGUGCUGu-------------- 2 -2,-4 --------------------------------------------------CCACUGCCCCAGGUGCUGC-------------- 2 -2,-3 --------------------------------------------------CCACUGCCCCAGGUGCUGCU------------- 28 -2,-2 --------------------------------------------------CCACUGCCCCAGGUGCUGCUG------------ 84 -2,-1 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGa----------- 15 -2,-1 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGaa---------- 7 -2,-1 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGu----------- 33 -2,-1 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGuu---------- 2 -2,-1 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGG----------- 276 -2,0 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGGa---------- 92 -2,0 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGGaa--------- 41 -2,0 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGGau--------- 17 -2,0 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGGu---------- 46 -2,0 --------------------------------------------------CCACUGCCCCAGGUGCUGCUGGuu--------- 4 -2,0 ---------------------------------------------------CACUGCCCCAGGUGCUGCUG------------ 2 -1,-1 ---------------------------------------------------CACUGCCCCAGGUGCUGCUGG----------- 7 -1,0 ---------------------------------------------------CACUGCCCCAGGUGCUGCUGGa---------- 5 -1,0 ---------------------------------------------------CACUGCCCCAGGUGCUGCUGGaa--------- 2 -1,0 ---------------------------------------------------CACUGCCCCAGGUGCUGCUGGu---------- 3 -1,0 ----------------------------------------------------ACUGCCCCAGGUGCUGCUG------------ 9 0,-1 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGaa---------- 2 0,-1 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGu----------- 8 0,-1 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGG----------- 459 0,0 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGGa---------- 83 0,0 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGGaa--------- 65 0,0 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGGau--------- 5 0,0 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGGu---------- 949 0,0 ----------------------------------------------------ACUGCCCCAGGUGCUGCUGGuu--------- 286 0,0 -----------------------------------------------------CUGCCCCAGGUGCUGCUGGu---------- 2 1,0 >hsa-mir-326 3pM:60-79 Tumor cucaucugucuguugggcuggaggcagggccuuugugaaggcggguggugcucagaucgCCUCUGGGCCCUUCCUCCAGccccgaggcggauuca -----------------------------------------------------------CCUCUGGGCCCUUCCUCC------------------ 29 0,-2 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCA----------------- 24 0,-1 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAa---------------- 4 0,-1 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAau--------------- 24 0,-1 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAu---------------- 2 0,-1 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAuu--------------- 24 0,-1 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAG---------------- 154 0,0 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAGa--------------- 140 0,0 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAGaa-------------- 2 0,0 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAGu--------------- 1184 0,0 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAGuu-------------- 261 0,0 -----------------------------------------------------------CCUCUGGGCCCUUCCUCCAGC--------------- 2 0,1 ------------------------------------------------------------CUCUGGGCCCUUCCUCCAGa--------------- 2 1,0 ------------------------------------------------------------CUCUGGGCCCUUCCUCCAGu--------------- 37 1,0 ------------------------------------------------------------CUCUGGGCCCUUCCUCCAGuu-------------- 10 1,0 -------------------------------------------------------------UCUGGGCCCUUCCUCCAGuu-------------- 4 2,0 >hsa-mir-328 3pM:48-69 Tumor uggagugggggggcaggaggggcucagggagaaagugcauacagcccCUGGCCCUCUCUGCCCUUCCGUccccug -----------------------------------------------CUGGCCCUCUCUGCCCUU---------- 8 0,-4 -----------------------------------------------CUGGCCCUCUCUGCCCUUa--------- 3 0,-4 -----------------------------------------------CUGGCCCUCUCUGCCCUUu--------- 6 0,-4 -----------------------------------------------CUGGCCCUCUCUGCCCUUC--------- 24 0,-3 -----------------------------------------------CUGGCCCUCUCUGCCCUUCa-------- 2 0,-3 -----------------------------------------------CUGGCCCUCUCUGCCCUUCC-------- 2 0,-2 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCa------- 2 0,-2 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCuu------ 4 0,-2 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCG------- 84 0,-1 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGa------ 95 0,-1 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGaa----- 4 0,-1 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGau----- 9 0,-1 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGc------ 3 0,-1 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGU------ 890 0,0 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGUa----- 49 0,0 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGUaa---- 7 0,0 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGUau---- 10 0,0 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGUu----- 326 0,0 -----------------------------------------------CUGGCCCUCUCUGCCCUUCCGUuu---- 136 0,0 ------------------------------------------------UGGCCCUCUCUGCCCUUCCGa------ 2 1,-1 ------------------------------------------------UGGCCCUCUCUGCCCUUCCGU------ 41 1,0 ------------------------------------------------UGGCCCUCUCUGCCCUUCCGUa----- 2 1,0 ------------------------------------------------UGGCCCUCUCUGCCCUUCCGUu----- 19 1,0 ------------------------------------------------UGGCCCUCUCUGCCCUUCCGUuu---- 6 1,0 >hsa-mir-329-1 3pM:50-71 Tumor gguaccugaagagagguuuucuggguuucuguuucuuuaaugaggacgaAACACACCUGGUUAACCUCUUUuccaguauc ------------GAGGUUUUCUGGGUUUCUGUUU---------------------------------------------- 2 -------------------------------------------------AACACACCUGGUUAACCUCU----------- 13 0,-2 -------------------------------------------------AACACACCUGGUUAACCUCUa---------- 2 0,-2 -------------------------------------------------AACACACCUGGUUAACCUCUau--------- 4 0,-2 -------------------------------------------------AACACACCUGGUUAACCUCUU---------- 64 0,-1 -------------------------------------------------AACACACCUGGUUAACCUCUUa--------- 10 0,-1 -------------------------------------------------AACACACCUGGUUAACCUCUUU--------- 112 0,0 --------------------------------------------------ACACACCUGGUUAACCUCU----------- 2 1,-2 --------------------------------------------------ACACACCUGGUUAACCUCUaa--------- 2 1,-2 --------------------------------------------------ACACACCUGGUUAACCUCUU---------- 2 1,-1 --------------------------------------------------ACACACCUGGUUAACCUCUUaa-------- 2 1,-1 --------------------------------------------------ACACACCUGGUUAACCUCUUU--------- 5 1,0 --------------------------------------------------ACACACCUGGUUAACCUCUUUa-------- 2 1,0 >hsa-mir-329-2 3pM:52-73 Tumor gugguaccugaagagagguuuucuggguuucuguuucuuuauugaggacgaAACACACCUGGUUAACCUCUUUuccaguaucaa --------------GAGGUUUUCUGGGUUUCUGUUU------------------------------------------------ 2 ---------------------------------------------------AACACACCUGGUUAACCUCU------------- 13 0,-2 ---------------------------------------------------AACACACCUGGUUAACCUCUa------------ 2 0,-2 ---------------------------------------------------AACACACCUGGUUAACCUCUau----------- 4 0,-2 ---------------------------------------------------AACACACCUGGUUAACCUCUU------------ 64 0,-1 ---------------------------------------------------AACACACCUGGUUAACCUCUUa----------- 10 0,-1 ---------------------------------------------------AACACACCUGGUUAACCUCUUU----------- 112 0,0 ----------------------------------------------------ACACACCUGGUUAACCUCU------------- 2 1,-2 ----------------------------------------------------ACACACCUGGUUAACCUCUaa----------- 2 1,-2 ----------------------------------------------------ACACACCUGGUUAACCUCUU------------ 2 1,-1 ----------------------------------------------------ACACACCUGGUUAACCUCUUaa---------- 2 1,-1 ----------------------------------------------------ACACACCUGGUUAACCUCUUU----------- 5 1,0 ----------------------------------------------------ACACACCUGGUUAACCUCUUUa---------- 2 1,0 >hsa-mir-330 5p:18-39;3p:57-79 Tumor cuuuggcgaucacugccUCUCUGGGCCUGUGUCUUAGGCucugcaagaucaaccgaGCAAAGCACACGGCCUGCAGAGAggcagcgcucugccc -----------------UCUCUGGGCCUGUGUCUUAG--------------------------------------------------------- 10 0,-2 -----------------UCUCUGGGCCUGUGUCUUAGG-------------------------------------------------------- 22 0,-1 -----------------UCUCUGGGCCUGUGUCUUAGGa------------------------------------------------------- 20 0,-1 -----------------UCUCUGGGCCUGUGUCUUAGGu------------------------------------------------------- 3 0,-1 -----------------UCUCUGGGCCUGUGUCUUAGGC------------------------------------------------------- 21 0,0 -----------------UCUCUGGGCCUGUGUCUUAGGCa------------------------------------------------------ 8 0,0 -----------------UCUCUGGGCCUGUGUCUUAGGCau----------------------------------------------------- 5 0,0 -----------------UCUCUGGGCCUGUGUCUUAGGCU------------------------------------------------------ 70 0,1 -----------------UCUCUGGGCCUGUGUCUUAGGCUa----------------------------------------------------- 2 0,1 -----------------UCUCUGGGCCUGUGUCUUAGGCUu----------------------------------------------------- 7 0,1 ------------------CUCUGGGCCUGUGUCUUAG--------------------------------------------------------- 2 1,-2 ------------------CUCUGGGCCUGUGUCUUAGGa------------------------------------------------------- 2 1,-1 --------------------------------------------------------GCAAAGCACACGGCCUGCAGA----------------- 40 0,-2 --------------------------------------------------------GCAAAGCACACGGCCUGCAGAa---------------- 4 0,-2 --------------------------------------------------------GCAAAGCACACGGCCUGCAGAG---------------- 102 0,-1 --------------------------------------------------------GCAAAGCACACGGCCUGCAGAGu--------------- 29 0,-1 --------------------------------------------------------GCAAAGCACACGGCCUGCAGAGA--------------- 286 0,0 --------------------------------------------------------GCAAAGCACACGGCCUGCAGAGAa-------------- 2 0,0 --------------------------------------------------------GCAAAGCACACGGCCUGCAGAGAu-------------- 4 0,0 --------------------------------------------------------GCAAAGCACACGGCCUGCAGAGAG-------------- 4 0,1 --------------------------------------------------------GCAAAGCACACGGCCUGCAGAGAGu------------- 2 0,1 ---------------------------------------------------------CAAAGCACACGGCCUGCAGAG---------------- 14 1,-1 ---------------------------------------------------------CAAAGCACACGGCCUGCAGAGA--------------- 116 1,0 ---------------------------------------------------------CAAAGCACACGGCCUGCAGAGAa-------------- 8 1,0 ---------------------------------------------------------CAAAGCACACGGCCUGCAGAGAu-------------- 2 1,0 ---------------------------------------------------------CAAAGCACACGGCCUGCAGAGAG-------------- 34 1,1 ---------------------------------------------------------CAAAGCACACGGCCUGCAGAGAGa------------- 2 1,1 ---------------------------------------------------------CAAAGCACACGGCCUGCAGAGAGu------------- 15 1,1 ---------------------------------------------------------CAAAGCACACGGCCUGCAGAGAGG------------- 7 1,2 ---------------------------------------------------------CAAAGCACACGGCCUGCAGAGAGGu------------ 2 1,2 ----------------------------------------------------------AAAGCACACGGCCUGCAGAGA--------------- 20 2,0 ----------------------------------------------------------AAAGCACACGGCCUGCAGAGAG-------------- 8 2,1 ----------------------------------------------------------AAAGCACACGGCCUGCAGAGAGa------------- 2 2,1 ----------------------------------------------------------AAAGCACACGGCCUGCAGAGAGG------------- 2 2,2 >hsa-mir-331 5p:26-47;3p:61-81 Tumor gaguuugguuuuguuuggguuuguuCUAGGUAUGGUCCCAGGGAUCCcagaucaaaccagGCCCCUGGGCCUAUCCUAGAAccaaccuaagcuc -----------------------UUCUAGGUAUGGUCCCAGGGAU------------------------------------------------- 39 -2,-2 -----------------------UUCUAGGUAUGGUCCCAGGGAUu------------------------------------------------ 9 -2,-2 -----------------------UUCUAGGUAUGGUCCCAGGGAUC------------------------------------------------ 6 -2,-1 ------------------------UCUAGGUAUGGUCCCAGGGAU------------------------------------------------- 24 -1,-2 ------------------------UCUAGGUAUGGUCCCAGGGAUa------------------------------------------------ 2 -1,-2 ------------------------UCUAGGUAUGGUCCCAGGGAUC------------------------------------------------ 17 -1,-1 ------------------------UCUAGGUAUGGUCCCAGGGAUCC----------------------------------------------- 5 -1,0 ------------------------UCUAGGUAUGGUCCCAGGGAUCCa---------------------------------------------- 2 -1,0 -------------------------CUAGGUAUGGUCCCAGGGA-------------------------------------------------- 2 0,-3 -------------------------CUAGGUAUGGUCCCAGGGAU------------------------------------------------- 113 0,-2 -------------------------CUAGGUAUGGUCCCAGGGAUu------------------------------------------------ 5 0,-2 -------------------------CUAGGUAUGGUCCCAGGGAUC------------------------------------------------ 199 0,-1 -------------------------CUAGGUAUGGUCCCAGGGAUCu----------------------------------------------- 20 0,-1 -------------------------CUAGGUAUGGUCCCAGGGAUCC----------------------------------------------- 40 0,0 --------------------------UAGGUAUGGUCCCAGGGAUC------------------------------------------------ 2 1,-1 --------------------------UAGGUAUGGUCCCAGGGAUCC----------------------------------------------- 2 1,0 ------------------------------------------------------------GCCCCUGGGCCUAUCCUA---------------- 19 0,-3 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAuu-------------- 2 0,-3 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAG--------------- 221 0,-2 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGc-------------- 25 0,-2 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGu-------------- 54 0,-2 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGA-------------- 7194 0,-1 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAc------------- 723 0,-1 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAg------------- 6 0,-1 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAu------------- 236 0,-1 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAuu------------ 179 0,-1 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAA------------- 4974 0,0 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAAa------------ 2529 0,0 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAAaa----------- 275 0,0 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAAau----------- 56 0,0 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAAg------------ 56 0,0 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAAu------------ 3953 0,0 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAAuu----------- 202 0,0 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAAC------------ 130 0,1 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAACa----------- 2 0,1 ------------------------------------------------------------GCCCCUGGGCCUAUCCUAGAACu----------- 6 0,1 -------------------------------------------------------------CCCCUGGGCCUAUCCUAGA-------------- 189 1,-1 -------------------------------------------------------------CCCCUGGGCCUAUCCUAGAc------------- 20 1,-1 -------------------------------------------------------------CCCCUGGGCCUAUCCUAGAu------------- 10 1,-1 -------------------------------------------------------------CCCCUGGGCCUAUCCUAGAuu------------ 12 1,-1 -------------------------------------------------------------CCCCUGGGCCUAUCCUAGAA------------- 73 1,0 -------------------------------------------------------------CCCCUGGGCCUAUCCUAGAAa------------ 29 1,0 -------------------------------------------------------------CCCCUGGGCCUAUCCUAGAAaa----------- 6 1,0 -------------------------------------------------------------CCCCUGGGCCUAUCCUAGAAu------------ 358 1,0 -------------------------------------------------------------CCCCUGGGCCUAUCCUAGAAuu----------- 94 1,0 -------------------------------------------------------------CCCCUGGGCCUAUCCUAGAAC------------ 2 1,1 --------------------------------------------------------------CCCUGGGCCUAUCCUAGA-------------- 2 2,-1 --------------------------------------------------------------CCCUGGGCCUAUCCUAGAA------------- 2 2,0 --------------------------------------------------------------CCCUGGGCCUAUCCUAGAAau----------- 2 2,0 --------------------------------------------------------------CCCUGGGCCUAUCCUAGAAu------------ 6 2,0 --------------------------------------------------------------CCCUGGGCCUAUCCUAGAAuu----------- 2 2,0 --------------------------------------------------------------CCCUGGGCCUAUCCUAGAACC----------- 2 2,2 >hsa-mir-335 MA:16-38;mi:52-73 Tumor uguuuugagcgggggUCAAGAGCAAUAACGAAAAAUGUuugucauaaaccgUUUUUCAUUAUUGCUCCUGACCuccucucauuugcuauauuca ---------------UCAAGAGCAAUAACGAAA------------------------------------------------------------- 10 0,-5 ---------------UCAAGAGCAAUAACGAAAA------------------------------------------------------------ 12 0,-4 ---------------UCAAGAGCAAUAACGAAAAA----------------------------------------------------------- 69 0,-3 ---------------UCAAGAGCAAUAACGAAAAAa---------------------------------------------------------- 4 0,-3 ---------------UCAAGAGCAAUAACGAAAAAaa--------------------------------------------------------- 2 0,-3 ---------------UCAAGAGCAAUAACGAAAAAU---------------------------------------------------------- 1335 0,-2 ---------------UCAAGAGCAAUAACGAAAAAUa--------------------------------------------------------- 14 0,-2 ---------------UCAAGAGCAAUAACGAAAAAUG--------------------------------------------------------- 3822 0,-1 ---------------UCAAGAGCAAUAACGAAAAAUGa-------------------------------------------------------- 221 0,-1 ---------------UCAAGAGCAAUAACGAAAAAUGc-------------------------------------------------------- 2 0,-1 ---------------UCAAGAGCAAUAACGAAAAAUGU-------------------------------------------------------- 3071 0,0 ---------------UCAAGAGCAAUAACGAAAAAUGUU------------------------------------------------------- 50 0,1 ---------------UCAAGAGCAAUAACGAAAAAUGUUa------------------------------------------------------ 2 0,1 ---------------UCAAGAGCAAUAACGAAAAAUGUUU------------------------------------------------------ 2 0,2 ----------------CAAGAGCAAUAACGAAAAAU---------------------------------------------------------- 14 1,-2 ----------------CAAGAGCAAUAACGAAAAAUG--------------------------------------------------------- 82 1,-1 ----------------CAAGAGCAAUAACGAAAAAUGU-------------------------------------------------------- 44 1,0 -----------------AAGAGCAAUAACGAAAAAU---------------------------------------------------------- 6 2,-2 -----------------AAGAGCAAUAACGAAAAAUG--------------------------------------------------------- 19 2,-1 -----------------AAGAGCAAUAACGAAAAAUGU-------------------------------------------------------- 32 2,0 --------------------------------------------------GUUUUUCAUUAUUGCUCCUG------------------------ 2 -1,-3 --------------------------------------------------GUUUUUCAUUAUUGCUCCUGA----------------------- 4 -1,-2 --------------------------------------------------GUUUUUCAUUAUUGCUCCUGAC---------------------- 65 -1,-1 --------------------------------------------------GUUUUUCAUUAUUGCUCCUGACa--------------------- 20 -1,-1 --------------------------------------------------GUUUUUCAUUAUUGCUCCUGACg--------------------- 2 -1,-1 --------------------------------------------------GUUUUUCAUUAUUGCUCCUGACu--------------------- 16 -1,-1 --------------------------------------------------GUUUUUCAUUAUUGCUCCUGACC--------------------- 163 -1,0 --------------------------------------------------GUUUUUCAUUAUUGCUCCUGACCa-------------------- 2 -1,0 ---------------------------------------------------UUUUUCAUUAUUGCUCCU------------------------- 8 0,-4 ---------------------------------------------------UUUUUCAUUAUUGCUCCUG------------------------ 5 0,-3 ---------------------------------------------------UUUUUCAUUAUUGCUCCUGA----------------------- 56 0,-2 ---------------------------------------------------UUUUUCAUUAUUGCUCCUGAa---------------------- 2 0,-2 ---------------------------------------------------UUUUUCAUUAUUGCUCCUGAC---------------------- 213 0,-1 ---------------------------------------------------UUUUUCAUUAUUGCUCCUGACa--------------------- 43 0,-1 ---------------------------------------------------UUUUUCAUUAUUGCUCCUGACu--------------------- 49 0,-1 ---------------------------------------------------UUUUUCAUUAUUGCUCCUGACC--------------------- 892 0,0 ---------------------------------------------------UUUUUCAUUAUUGCUCCUGACCa-------------------- 4 0,0 ----------------------------------------------------UUUUCAUUAUUGCUCCUGACCa-------------------- 2 1,0 -----------------------------------------------------UUUCAUUAUUGCUCCUGACCa-------------------- 2 2,0 >hsa-mir-337 5p:23-43;3p:61-82 Tumor guagucaguaguugggggguggGAACGGCUUCAUACAGGAGUUgaugcacaguuauccagCUCCUAUAUGAUGCCUUUCUUCauccccuucaa ----------------------GAACGGCUUCAUACAGGAGU--------------------------------------------------- 8 0,-1 ----------------------GAACGGCUUCAUACAGGAGUU-------------------------------------------------- 11 0,0 -----------------------AACGGCUUCAUACAGGAGUUGA------------------------------------------------ 2 1,2 ------------------------------------------------------------CUCCUAUAUGAUGCCUUUCU------------- 18 0,-2 ------------------------------------------------------------CUCCUAUAUGAUGCCUUUCUU------------ 24 0,-1 ------------------------------------------------------------CUCCUAUAUGAUGCCUUUCUUC----------- 71 0,0 -------------------------------------------------------------UCCUAUAUGAUGCCUUUCU------------- 6 1,-2 -------------------------------------------------------------UCCUAUAUGAUGCCUUUCUU------------ 32 1,-1 -------------------------------------------------------------UCCUAUAUGAUGCCUUUCUUC----------- 100 1,0 -------------------------------------------------------------UCCUAUAUGAUGCCUUUCUUCu---------- 2 1,0 >hsa-mir-338 5p:6-27;3p:42-63 Tumor ucuccAACAAUAUCCUGGUGCUGAGUGaugacucaggcgacUCCAGCAUCAGUGAUUUUGUUGaaga -----AACAAUAUCCUGGUGCUGAGa----------------------------------------- 2 0,-2 -----AACAAUAUCCUGGUGCUGAGU----------------------------------------- 226 0,-1 -----------------------------------------UCCAGCAUCAGUGAUUUUG------- 7 0,-3 -----------------------------------------UCCAGCAUCAGUGAUUUUGaa----- 2 0,-3 -----------------------------------------UCCAGCAUCAGUGAUUUUGU------ 51 0,-2 -----------------------------------------UCCAGCAUCAGUGAUUUUGUU----- 299 0,-1 -----------------------------------------UCCAGCAUCAGUGAUUUUGUUa---- 18 0,-1 -----------------------------------------UCCAGCAUCAGUGAUUUUGUUaa--- 8 0,-1 -----------------------------------------UCCAGCAUCAGUGAUUUUGUUu---- 2 0,-1 -----------------------------------------UCCAGCAUCAGUGAUUUUGUUG---- 86 0,0 -----------------------------------------UCCAGCAUCAGUGAUUUUGUUGu--- 11 0,0 -----------------------------------------UCCAGCAUCAGUGAUUUUGUUGA--- 758 0,1 -----------------------------------------UCCAGCAUCAGUGAUUUUGUUGAu-- 2 0,1 -----------------------------------------UCCAGCAUCAGUGAUUUUGUUGAA-- 20 0,2 -------------------------------------------CAGCAUCAGUGAUUUUGUUGA--- 2 2,1 >hsa-mir-339 5p:15-37;3p:50-72 Tumor cggggcggccgcucUCCCUGUCCUCCAGGAGCUCACGugugccugccugUGAGCGCCUCGACGACAGAGCCGgcgccugccccagugucugcgc -------------CUCCCUGUCCUCCAGGAGCU------------------------------------------------------------- 4 -1,-4 -------------CUCCCUGUCCUCCAGGAGCUCACG--------------------------------------------------------- 2 -1,0 --------------UCCCUGUCCUCCAGGAGC-------------------------------------------------------------- 61 0,-5 --------------UCCCUGUCCUCCAGGAGCa------------------------------------------------------------- 2 0,-5 --------------UCCCUGUCCUCCAGGAGCU------------------------------------------------------------- 590 0,-4 --------------UCCCUGUCCUCCAGGAGCUa------------------------------------------------------------ 21 0,-4 --------------UCCCUGUCCUCCAGGAGCUaa----------------------------------------------------------- 2 0,-4 --------------UCCCUGUCCUCCAGGAGCUau----------------------------------------------------------- 2 0,-4 --------------UCCCUGUCCUCCAGGAGCUg------------------------------------------------------------ 2 0,-4 --------------UCCCUGUCCUCCAGGAGCUu------------------------------------------------------------ 55 0,-4 --------------UCCCUGUCCUCCAGGAGCUuu----------------------------------------------------------- 2 0,-4 --------------UCCCUGUCCUCCAGGAGCUC------------------------------------------------------------ 963 0,-3 --------------UCCCUGUCCUCCAGGAGCUCc----------------------------------------------------------- 24 0,-3 --------------UCCCUGUCCUCCAGGAGCUCu----------------------------------------------------------- 71 0,-3 --------------UCCCUGUCCUCCAGGAGCUCA----------------------------------------------------------- 1980 0,-2 --------------UCCCUGUCCUCCAGGAGCUCAa---------------------------------------------------------- 174 0,-2 --------------UCCCUGUCCUCCAGGAGCUCAaa--------------------------------------------------------- 50 0,-2 --------------UCCCUGUCCUCCAGGAGCUCAau--------------------------------------------------------- 27 0,-2 --------------UCCCUGUCCUCCAGGAGCUCAg---------------------------------------------------------- 4 0,-2 --------------UCCCUGUCCUCCAGGAGCUCAu---------------------------------------------------------- 160 0,-2 --------------UCCCUGUCCUCCAGGAGCUCAuu--------------------------------------------------------- 36 0,-2 --------------UCCCUGUCCUCCAGGAGCUCAC---------------------------------------------------------- 388 0,-1 --------------UCCCUGUCCUCCAGGAGCUCACa--------------------------------------------------------- 127 0,-1 --------------UCCCUGUCCUCCAGGAGCUCACc--------------------------------------------------------- 4 0,-1 --------------UCCCUGUCCUCCAGGAGCUCACu--------------------------------------------------------- 108 0,-1 --------------UCCCUGUCCUCCAGGAGCUCACG--------------------------------------------------------- 2707 0,0 --------------UCCCUGUCCUCCAGGAGCUCACGa-------------------------------------------------------- 122 0,0 --------------UCCCUGUCCUCCAGGAGCUCACGau------------------------------------------------------- 2 0,0 --------------UCCCUGUCCUCCAGGAGCUCACGU-------------------------------------------------------- 146 0,1 --------------UCCCUGUCCUCCAGGAGCUCACGUu------------------------------------------------------- 7 0,1 ----------------CCUGUCCUCCAGGAGCUCA----------------------------------------------------------- 6 2,-2 ----------------CCUGUCCUCCAGGAGCUCACG--------------------------------------------------------- 15 2,0 -------------------------------------------------UGAGCGCCUCGACGACAG--------------------------- 7 0,-5 -------------------------------------------------UGAGCGCCUCGACGACAGA-------------------------- 153 0,-4 -------------------------------------------------UGAGCGCCUCGACGACAGAa------------------------- 5 0,-4 -------------------------------------------------UGAGCGCCUCGACGACAGAaa------------------------ 2 0,-4 -------------------------------------------------UGAGCGCCUCGACGACAGAG------------------------- 597 0,-3 -------------------------------------------------UGAGCGCCUCGACGACAGAGa------------------------ 117 0,-3 -------------------------------------------------UGAGCGCCUCGACGACAGAGaa----------------------- 2 0,-3 -------------------------------------------------UGAGCGCCUCGACGACAGAGu------------------------ 25 0,-3 -------------------------------------------------UGAGCGCCUCGACGACAGAGuu----------------------- 2 0,-3 -------------------------------------------------UGAGCGCCUCGACGACAGAGC------------------------ 1024 0,-2 -------------------------------------------------UGAGCGCCUCGACGACAGAGCa----------------------- 9 0,-2 -------------------------------------------------UGAGCGCCUCGACGACAGAGCaa---------------------- 2 0,-2 -------------------------------------------------UGAGCGCCUCGACGACAGAGCu----------------------- 102 0,-2 -------------------------------------------------UGAGCGCCUCGACGACAGAGCuu---------------------- 4 0,-2 -------------------------------------------------UGAGCGCCUCGACGACAGAGCC----------------------- 448 0,-1 -------------------------------------------------UGAGCGCCUCGACGACAGAGCCa---------------------- 88 0,-1 -------------------------------------------------UGAGCGCCUCGACGACAGAGCCau--------------------- 16 0,-1 -------------------------------------------------UGAGCGCCUCGACGACAGAGCCu---------------------- 69 0,-1 -------------------------------------------------UGAGCGCCUCGACGACAGAGCCuu--------------------- 5 0,-1 -------------------------------------------------UGAGCGCCUCGACGACAGAGCCG---------------------- 1117 0,0 -------------------------------------------------UGAGCGCCUCGACGACAGAGCCGa--------------------- 48 0,0 -------------------------------------------------UGAGCGCCUCGACGACAGAGCCGau-------------------- 3 0,0 -------------------------------------------------UGAGCGCCUCGACGACAGAGCCGu--------------------- 125 0,0 -------------------------------------------------UGAGCGCCUCGACGACAGAGCCGuu-------------------- 7 0,0 --------------------------------------------------GAGCGCCUCGACGACAGAG------------------------- 7 1,-3 --------------------------------------------------GAGCGCCUCGACGACAGAGa------------------------ 2 1,-3 --------------------------------------------------GAGCGCCUCGACGACAGAGC------------------------ 18 1,-2 --------------------------------------------------GAGCGCCUCGACGACAGAGCC----------------------- 9 1,-1 --------------------------------------------------GAGCGCCUCGACGACAGAGCCG---------------------- 115 1,0 --------------------------------------------------GAGCGCCUCGACGACAGAGCCGa--------------------- 6 1,0 --------------------------------------------------GAGCGCCUCGACGACAGAGCCGu--------------------- 6 1,0 ---------------------------------------------------AGCGCCUCGACGACAGAGC------------------------ 19 2,-2 ---------------------------------------------------AGCGCCUCGACGACAGAGCC----------------------- 33 2,-1 ---------------------------------------------------AGCGCCUCGACGACAGAGCCu---------------------- 2 2,-1 ---------------------------------------------------AGCGCCUCGACGACAGAGCCG---------------------- 449 2,0 ---------------------------------------------------AGCGCCUCGACGACAGAGCCGa--------------------- 37 2,0 ---------------------------------------------------AGCGCCUCGACGACAGAGCCGaa-------------------- 2 2,0 ---------------------------------------------------AGCGCCUCGACGACAGAGCCGu--------------------- 26 2,0 ---------------------------------------------------AGCGCCUCGACGACAGAGCCGG--------------------- 2 2,1 >hsa-mir-33a MA:6-26;mi:46-67 Tumor cugugGUGCAUUGUAGUUGCAUUGCAuguucuggugguacccaugCAAUGUUUCCACAGUGCAUCACag -----GUGCAUUGUAGUUGCAUU---------------------------------------------- 552 0,-3 -----GUGCAUUGUAGUUGCAUUu--------------------------------------------- 6 0,-3 -----GUGCAUUGUAGUUGCAUUG--------------------------------------------- 881 0,-2 -----GUGCAUUGUAGUUGCAUUGa-------------------------------------------- 255 0,-2 -----GUGCAUUGUAGUUGCAUUGaa------------------------------------------- 8 0,-2 -----GUGCAUUGUAGUUGCAUUGu-------------------------------------------- 190 0,-2 -----GUGCAUUGUAGUUGCAUUGC-------------------------------------------- 15053 0,-1 -----GUGCAUUGUAGUUGCAUUGCc------------------------------------------- 99 0,-1 -----GUGCAUUGUAGUUGCAUUGCg------------------------------------------- 17 0,-1 -----GUGCAUUGUAGUUGCAUUGCu------------------------------------------- 50 0,-1 -----GUGCAUUGUAGUUGCAUUGCA------------------------------------------- 9942 0,0 -----GUGCAUUGUAGUUGCAUUGCAa------------------------------------------ 1164 0,0 -----GUGCAUUGUAGUUGCAUUGCAaa----------------------------------------- 51 0,0 -----GUGCAUUGUAGUUGCAUUGCAau----------------------------------------- 27 0,0 -----GUGCAUUGUAGUUGCAUUGCAc------------------------------------------ 7 0,0 -----GUGCAUUGUAGUUGCAUUGCAg------------------------------------------ 45 0,0 -----GUGCAUUGUAGUUGCAUUGCAU------------------------------------------ 55 0,1 -----GUGCAUUGUAGUUGCAUUGCAUu----------------------------------------- 9 0,1 -----GUGCAUUGUAGUUGCAUUGCAUG----------------------------------------- 13 0,2 -------------------------------------------UGCAAUGUUUCCACAGUGCAUC---- 2 -2,-2 ---------------------------------------------CAAUGUUUCCACAGUGCA------ 2 0,-4 ---------------------------------------------CAAUGUUUCCACAGUGCAU----- 126 0,-3 ---------------------------------------------CAAUGUUUCCACAGUGCAUa---- 2 0,-3 ---------------------------------------------CAAUGUUUCCACAGUGCAUC---- 58 0,-2 ---------------------------------------------CAAUGUUUCCACAGUGCAUCu--- 2 0,-2 ---------------------------------------------CAAUGUUUCCACAGUGCAUCA--- 292 0,-1 ---------------------------------------------CAAUGUUUCCACAGUGCAUCAa-- 4 0,-1 ---------------------------------------------CAAUGUUUCCACAGUGCAUCAaa- 2 0,-1 ---------------------------------------------CAAUGUUUCCACAGUGCAUCAau- 2 0,-1 ---------------------------------------------CAAUGUUUCCACAGUGCAUCAu-- 54 0,-1 ----------------------------------------------AAUGUUUCCACAGUGCAU----- 2 1,-3 ----------------------------------------------AAUGUUUCCACAGUGCAUC---- 2 1,-2 ----------------------------------------------AAUGUUUCCACAGUGCAUCA--- 6 1,-1 >hsa-mir-33b MA:16-35;mi:54-75 Tumor gcgggcggccccgcgGUGCAUUGCUGUUGCAUUGCacgugugugaggcgggugCAGUGCCUCGGCAGUGCAGCCCggagccggccccuggcaccac ---------------GUGCAUUGCUGUUGCAUU--------------------------------------------------------------- 126 0,-2 ---------------GUGCAUUGCUGUUGCAUUa-------------------------------------------------------------- 4 0,-2 ---------------GUGCAUUGCUGUUGCAUUu-------------------------------------------------------------- 6 0,-2 ---------------GUGCAUUGCUGUUGCAUUG-------------------------------------------------------------- 1456 0,-1 ---------------GUGCAUUGCUGUUGCAUUGa------------------------------------------------------------- 585 0,-1 ---------------GUGCAUUGCUGUUGCAUUGaa------------------------------------------------------------ 8 0,-1 ---------------GUGCAUUGCUGUUGCAUUGau------------------------------------------------------------ 2 0,-1 ---------------GUGCAUUGCUGUUGCAUUGg------------------------------------------------------------- 2 0,-1 ---------------GUGCAUUGCUGUUGCAUUGu------------------------------------------------------------- 192 0,-1 ---------------GUGCAUUGCUGUUGCAUUGC------------------------------------------------------------- 4407 0,0 ---------------GUGCAUUGCUGUUGCAUUGCc------------------------------------------------------------ 9 0,0 ---------------GUGCAUUGCUGUUGCAUUGCg------------------------------------------------------------ 2 0,0 ---------------GUGCAUUGCUGUUGCAUUGCu------------------------------------------------------------ 11 0,0 ---------------GUGCAUUGCUGUUGCAUUGCA------------------------------------------------------------ 1084 0,1 ---------------GUGCAUUGCUGUUGCAUUGCAa----------------------------------------------------------- 44 0,1 ---------------GUGCAUUGCUGUUGCAUUGCAaa---------------------------------------------------------- 2 0,1 ---------------------------------------------------UGCAGUGCCUCGGCAGUGC-------------------------- 2 -2,-5 ---------------------------------------------------UGCAGUGCCUCGGCAGUGCAGu----------------------- 2 -2,-3 ---------------------------------------------------UGCAGUGCCUCGGCAGUGCAGC----------------------- 18 -2,-2 ----------------------------------------------------GCAGUGCCUCGGCAGUGCAGC----------------------- 6 -1,-2 -----------------------------------------------------CAGUGCCUCGGCAGUGCAG------------------------ 2 0,-3 -----------------------------------------------------CAGUGCCUCGGCAGUGCAGC----------------------- 7 0,-2 -----------------------------------------------------CAGUGCCUCGGCAGUGCAGCC---------------------- 117 0,-1 -----------------------------------------------------CAGUGCCUCGGCAGUGCAGCCa--------------------- 2 0,-1 -----------------------------------------------------CAGUGCCUCGGCAGUGCAGCCau-------------------- 2 0,-1 ------------------------------------------------------AGUGCCUCGGCAGUGCAGCC---------------------- 2 1,-1 >hsa-mir-340 MA:16-37;mi:58-79 Tumor uuguaccuggugugaUUAUAAAGCAAUGAGACUGAUUgucauaugucguuugugggaUCCGUCUCAGUUACUUUAUAGCcauaccugguaucuua ---------------UUAUAAAGCAAUGAGACU-------------------------------------------------------------- 14 0,-4 ---------------UUAUAAAGCAAUGAGACUG------------------------------------------------------------- 55 0,-3 ---------------UUAUAAAGCAAUGAGACUGu------------------------------------------------------------ 19 0,-3 ---------------UUAUAAAGCAAUGAGACUGA------------------------------------------------------------ 1056 0,-2 ---------------UUAUAAAGCAAUGAGACUGAa----------------------------------------------------------- 55 0,-2 ---------------UUAUAAAGCAAUGAGACUGAaa---------------------------------------------------------- 34 0,-2 ---------------UUAUAAAGCAAUGAGACUGAU----------------------------------------------------------- 3929 0,-1 ---------------UUAUAAAGCAAUGAGACUGAUa---------------------------------------------------------- 366 0,-1 ---------------UUAUAAAGCAAUGAGACUGAUaa--------------------------------------------------------- 32 0,-1 ---------------UUAUAAAGCAAUGAGACUGAUau--------------------------------------------------------- 6 0,-1 ---------------UUAUAAAGCAAUGAGACUGAUc---------------------------------------------------------- 4 0,-1 ---------------UUAUAAAGCAAUGAGACUGAUg---------------------------------------------------------- 2 0,-1 ---------------UUAUAAAGCAAUGAGACUGAUU---------------------------------------------------------- 9037 0,0 ---------------UUAUAAAGCAAUGAGACUGAUUa--------------------------------------------------------- 156 0,0 ---------------UUAUAAAGCAAUGAGACUGAUUaa-------------------------------------------------------- 10 0,0 ---------------UUAUAAAGCAAUGAGACUGAUUau-------------------------------------------------------- 2 0,0 ---------------UUAUAAAGCAAUGAGACUGAUUu--------------------------------------------------------- 132 0,0 ---------------UUAUAAAGCAAUGAGACUGAUUuu-------------------------------------------------------- 4 0,0 ---------------UUAUAAAGCAAUGAGACUGAUUG--------------------------------------------------------- 9 0,1 ---------------UUAUAAAGCAAUGAGACUGAUUGa-------------------------------------------------------- 2 0,1 ----------------UAUAAAGCAAUGAGACUGA------------------------------------------------------------ 8 1,-2 ----------------UAUAAAGCAAUGAGACUGAaa---------------------------------------------------------- 2 1,-2 ----------------UAUAAAGCAAUGAGACUGAU----------------------------------------------------------- 77 1,-1 ----------------UAUAAAGCAAUGAGACUGAUU---------------------------------------------------------- 157 1,0 ----------------UAUAAAGCAAUGAGACUGAUUa--------------------------------------------------------- 6 1,0 -----------------AUAAAGCAAUGAGACUGAU----------------------------------------------------------- 6 2,-1 -----------------AUAAAGCAAUGAGACUGAUU---------------------------------------------------------- 6 2,0 ---------------------------------------------------------UCCGUCUCAGUUACUUUAUAG----------------- 50 0,-1 ---------------------------------------------------------UCCGUCUCAGUUACUUUAUAGa---------------- 7 0,-1 ---------------------------------------------------------UCCGUCUCAGUUACUUUAUAGC---------------- 260 0,0 ---------------------------------------------------------UCCGUCUCAGUUACUUUAUAGCu--------------- 5 0,0 ---------------------------------------------------------UCCGUCUCAGUUACUUUAUAGCC--------------- 212 0,1 ----------------------------------------------------------CCGUCUCAGUUACUUUAUAGCC--------------- 6 1,1 >hsa-mir-342 5p:19-39;3p:61-83 Tumor gaaacugggcucaaggugAGGGGUGCUAUCUGUGAUUGAgggacaugguuaauggaauugUCUCACACAGAAAUCGCACCCGUcaccuuggccuacuua ------------------AGGGGUGCUAUCUGUGAU--------------------------------------------------------------- 2 0,-3 ------------------AGGGGUGCUAUCUGUGAUU-------------------------------------------------------------- 33 0,-2 ------------------AGGGGUGCUAUCUGUGAUUG------------------------------------------------------------- 51 0,-1 ------------------AGGGGUGCUAUCUGUGAUUGu------------------------------------------------------------ 4 0,-1 ------------------AGGGGUGCUAUCUGUGAUUGA------------------------------------------------------------ 505 0,0 ------------------AGGGGUGCUAUCUGUGAUUGAa----------------------------------------------------------- 16 0,0 ------------------AGGGGUGCUAUCUGUGAUUGAc----------------------------------------------------------- 2 0,0 ------------------AGGGGUGCUAUCUGUGAUUGAG----------------------------------------------------------- 935 0,1 ------------------AGGGGUGCUAUCUGUGAUUGAGa---------------------------------------------------------- 369 0,1 ------------------AGGGGUGCUAUCUGUGAUUGAGu---------------------------------------------------------- 31 0,1 ------------------AGGGGUGCUAUCUGUGAUUGAGG---------------------------------------------------------- 651 0,2 ------------------AGGGGUGCUAUCUGUGAUUGAGGa--------------------------------------------------------- 23 0,2 ------------------AGGGGUGCUAUCUGUGAUUGAGGu--------------------------------------------------------- 10 0,2 ------------------AGGGGUGCUAUCUGUGAUUGAGGG--------------------------------------------------------- 17 0,3 ------------------AGGGGUGCUAUCUGUGAUUGAGGGA-------------------------------------------------------- 38 0,4 -------------------GGGGUGCUAUCUGUGAUUG------------------------------------------------------------- 4 1,-1 -------------------GGGGUGCUAUCUGUGAUUGA------------------------------------------------------------ 87 1,0 -------------------GGGGUGCUAUCUGUGAUUGAG----------------------------------------------------------- 260 1,1 -------------------GGGGUGCUAUCUGUGAUUGAGa---------------------------------------------------------- 50 1,1 -------------------GGGGUGCUAUCUGUGAUUGAGaa--------------------------------------------------------- 2 1,1 -------------------GGGGUGCUAUCUGUGAUUGAGu---------------------------------------------------------- 5 1,1 -------------------GGGGUGCUAUCUGUGAUUGAGG---------------------------------------------------------- 289 1,2 -------------------GGGGUGCUAUCUGUGAUUGAGGa--------------------------------------------------------- 32 1,2 -------------------GGGGUGCUAUCUGUGAUUGAGGu--------------------------------------------------------- 2 1,2 -------------------GGGGUGCUAUCUGUGAUUGAGGG--------------------------------------------------------- 28 1,3 -------------------GGGGUGCUAUCUGUGAUUGAGGGu-------------------------------------------------------- 2 1,3 -------------------GGGGUGCUAUCUGUGAUUGAGGGA-------------------------------------------------------- 51 1,4 -------------------GGGGUGCUAUCUGUGAUUGAGGGAa------------------------------------------------------- 4 1,4 -------------------GGGGUGCUAUCUGUGAUUGAGGGAu------------------------------------------------------- 14 1,4 -------------------GGGGUGCUAUCUGUGAUUGAGGGAC------------------------------------------------------- 127 1,5 ------------------------------------------------------------UCUCACACAGAAAUCGCA--------------------- 162 0,-5 ------------------------------------------------------------UCUCACACAGAAAUCGCAa-------------------- 25 0,-5 ------------------------------------------------------------UCUCACACAGAAAUCGCAaa------------------- 5 0,-5 ------------------------------------------------------------UCUCACACAGAAAUCGCAC-------------------- 159 0,-4 ------------------------------------------------------------UCUCACACAGAAAUCGCACa------------------- 2 0,-4 ------------------------------------------------------------UCUCACACAGAAAUCGCACC------------------- 609 0,-3 ------------------------------------------------------------UCUCACACAGAAAUCGCACCa------------------ 2 0,-3 ------------------------------------------------------------UCUCACACAGAAAUCGCACCC------------------ 390 0,-2 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCa----------------- 4 0,-2 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCau---------------- 23 0,-2 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCu----------------- 2 0,-2 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCuu---------------- 24 0,-2 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCG----------------- 6998 0,-1 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGa---------------- 571 0,-1 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGaa--------------- 10 0,-1 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGc---------------- 114 0,-1 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGg---------------- 14 0,-1 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGU---------------- 22304 0,0 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGUa--------------- 340 0,0 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGUaa-------------- 31 0,0 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGUau-------------- 26 0,0 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGUg--------------- 14 0,0 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGUu--------------- 951 0,0 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGUuu-------------- 22 0,0 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGUC--------------- 11565 0,1 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGUCc-------------- 6 0,1 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGUCg-------------- 12 0,1 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGUCu-------------- 2077 0,1 ------------------------------------------------------------UCUCACACAGAAAUCGCACCCGUCA-------------- 652 0,2 -------------------------------------------------------------CUCACACAGAAAUCGCACC------------------- 4 1,-3 -------------------------------------------------------------CUCACACAGAAAUCGCACCC------------------ 6 1,-2 -------------------------------------------------------------CUCACACAGAAAUCGCACCCG----------------- 204 1,-1 -------------------------------------------------------------CUCACACAGAAAUCGCACCCGa---------------- 5 1,-1 -------------------------------------------------------------CUCACACAGAAAUCGCACCCGU---------------- 738 1,0 -------------------------------------------------------------CUCACACAGAAAUCGCACCCGUa--------------- 6 1,0 -------------------------------------------------------------CUCACACAGAAAUCGCACCCGUu--------------- 7 1,0 -------------------------------------------------------------CUCACACAGAAAUCGCACCCGUC--------------- 390 1,1 -------------------------------------------------------------CUCACACAGAAAUCGCACCCGUCu-------------- 79 1,1 -------------------------------------------------------------CUCACACAGAAAUCGCACCCGUCA-------------- 14 1,2 --------------------------------------------------------------UCACACAGAAAUCGCACCCG----------------- 34 2,-1 --------------------------------------------------------------UCACACAGAAAUCGCACCCGa---------------- 2 2,-1 --------------------------------------------------------------UCACACAGAAAUCGCACCCGaa--------------- 2 2,-1 --------------------------------------------------------------UCACACAGAAAUCGCACCCGU---------------- 308 2,0 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUa--------------- 27 2,0 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUaa-------------- 44 2,0 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUau-------------- 5 2,0 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUu--------------- 11 2,0 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUuu-------------- 2 2,0 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUC--------------- 588 2,1 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUCc-------------- 3 2,1 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUCg-------------- 16 2,1 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUCu-------------- 262 2,1 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUCuu------------- 3 2,1 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUCA-------------- 1137 2,2 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUCAa------------- 14 2,2 --------------------------------------------------------------UCACACAGAAAUCGCACCCGUCAu------------- 32 2,2 >hsa-mir-345 5pM:18-39 Tumor acccaaacccuaggucuGCUGACUCCUAGUCCAGGGCUCgugauggcuggugggcccugaacgaggggucuggaggccuggguuugaauaucgacagc -----------------GCUGACUCCUAGUCCAGG--------------------------------------------------------------- 87 0,-4 -----------------GCUGACUCCUAGUCCAGGa-------------------------------------------------------------- 11 0,-4 -----------------GCUGACUCCUAGUCCAGGaa------------------------------------------------------------- 3 0,-4 -----------------GCUGACUCCUAGUCCAGGau------------------------------------------------------------- 7 0,-4 -----------------GCUGACUCCUAGUCCAGGG-------------------------------------------------------------- 371 0,-3 -----------------GCUGACUCCUAGUCCAGGGa------------------------------------------------------------- 134 0,-3 -----------------GCUGACUCCUAGUCCAGGGaa------------------------------------------------------------ 121 0,-3 -----------------GCUGACUCCUAGUCCAGGGau------------------------------------------------------------ 44 0,-3 -----------------GCUGACUCCUAGUCCAGGGu------------------------------------------------------------- 74 0,-3 -----------------GCUGACUCCUAGUCCAGGGuu------------------------------------------------------------ 11 0,-3 -----------------GCUGACUCCUAGUCCAGGGC------------------------------------------------------------- 865 0,-2 -----------------GCUGACUCCUAGUCCAGGGCa------------------------------------------------------------ 84 0,-2 -----------------GCUGACUCCUAGUCCAGGGCaa----------------------------------------------------------- 47 0,-2 -----------------GCUGACUCCUAGUCCAGGGCau----------------------------------------------------------- 33 0,-2 -----------------GCUGACUCCUAGUCCAGGGCc------------------------------------------------------------ 4 0,-2 -----------------GCUGACUCCUAGUCCAGGGCU------------------------------------------------------------ 7170 0,-1 -----------------GCUGACUCCUAGUCCAGGGCUa----------------------------------------------------------- 386 0,-1 -----------------GCUGACUCCUAGUCCAGGGCUaa---------------------------------------------------------- 290 0,-1 -----------------GCUGACUCCUAGUCCAGGGCUau---------------------------------------------------------- 507 0,-1 -----------------GCUGACUCCUAGUCCAGGGCUg----------------------------------------------------------- 42 0,-1 -----------------GCUGACUCCUAGUCCAGGGCUu----------------------------------------------------------- 1249 0,-1 -----------------GCUGACUCCUAGUCCAGGGCUuu---------------------------------------------------------- 661 0,-1 -----------------GCUGACUCCUAGUCCAGGGCUC----------------------------------------------------------- 3293 0,0 -----------------GCUGACUCCUAGUCCAGGGCUCa---------------------------------------------------------- 993 0,0 -----------------GCUGACUCCUAGUCCAGGGCUCaa--------------------------------------------------------- 37 0,0 -----------------GCUGACUCCUAGUCCAGGGCUCau--------------------------------------------------------- 56 0,0 -----------------GCUGACUCCUAGUCCAGGGCUCc---------------------------------------------------------- 21 0,0 -----------------GCUGACUCCUAGUCCAGGGCUCu---------------------------------------------------------- 1830 0,0 -----------------GCUGACUCCUAGUCCAGGGCUCuu--------------------------------------------------------- 327 0,0 -----------------GCUGACUCCUAGUCCAGGGCUCG---------------------------------------------------------- 34 0,1 -----------------GCUGACUCCUAGUCCAGGGCUCGa--------------------------------------------------------- 4 0,1 -----------------GCUGACUCCUAGUCCAGGGCUCGU--------------------------------------------------------- 2 0,2 -------------------UGACUCCUAGUCCAGGGCU------------------------------------------------------------ 11 2,-1 -------------------UGACUCCUAGUCCAGGGCUu----------------------------------------------------------- 3 2,-1 -------------------UGACUCCUAGUCCAGGGCUC----------------------------------------------------------- 8 2,0 -----------------------------------------------------GCCCUGAACGAGGGGUCUGGAG----------------------- 2 ------------------------------------------------------CCCUGAACGAGGGGUCUGGAG----------------------- 2 >hsa-mir-346 5pM:20-42 Tumor ggucucuguguugggcgucUGUCUGCCCGCAUGCCUGCCUCUcuguugcucugaaggaggcaggggcugggccugcagcugccugggcagagcgg -------------------UGUCUGCCCGCAUGCCUGCCUCU----------------------------------------------------- 2 0,0 >hsa-mir-34a MA:22-43;mi:64-85 Tumor ggccagcugugaguguuucuuUGGCAGUGUCUUAGCUGGUUGUugugagcaauaguaaggaagCAAUCAGCAAGUAUACUGCCCUagaagugcugcacguuguggggccc -------------------UUUGGCAGUGUCUUAGCUGGUU--------------------------------------------------------------------- 2 -2,-2 -------------------UUUGGCAGUGUCUUAGCUGGUUG-------------------------------------------------------------------- 2 -2,-1 -------------------UUUGGCAGUGUCUUAGCUGGUUGU------------------------------------------------------------------- 2 -2,0 --------------------UUGGCAGUGUCUUAGCUGGU---------------------------------------------------------------------- 4 -1,-3 --------------------UUGGCAGUGUCUUAGCUGGUU--------------------------------------------------------------------- 19 -1,-2 --------------------UUGGCAGUGUCUUAGCUGGUUG-------------------------------------------------------------------- 56 -1,-1 --------------------UUGGCAGUGUCUUAGCUGGUUGa------------------------------------------------------------------- 18 -1,-1 --------------------UUGGCAGUGUCUUAGCUGGUUGU------------------------------------------------------------------- 75 -1,0 --------------------UUGGCAGUGUCUUAGCUGGUUGUU------------------------------------------------------------------ 19 -1,1 --------------------UUGGCAGUGUCUUAGCUGGUUGUUa----------------------------------------------------------------- 2 -1,1 ---------------------UGGCAGUGUCUUAGCUGG----------------------------------------------------------------------- 195 0,-4 ---------------------UGGCAGUGUCUUAGCUGGa---------------------------------------------------------------------- 16 0,-4 ---------------------UGGCAGUGUCUUAGCUGGaa--------------------------------------------------------------------- 9 0,-4 ---------------------UGGCAGUGUCUUAGCUGGU---------------------------------------------------------------------- 244 0,-3 ---------------------UGGCAGUGUCUUAGCUGGUa--------------------------------------------------------------------- 27 0,-3 ---------------------UGGCAGUGUCUUAGCUGGUaa-------------------------------------------------------------------- 21 0,-3 ---------------------UGGCAGUGUCUUAGCUGGUau-------------------------------------------------------------------- 7 0,-3 ---------------------UGGCAGUGUCUUAGCUGGUU--------------------------------------------------------------------- 1142 0,-2 ---------------------UGGCAGUGUCUUAGCUGGUUa-------------------------------------------------------------------- 53 0,-2 ---------------------UGGCAGUGUCUUAGCUGGUUaa------------------------------------------------------------------- 62 0,-2 ---------------------UGGCAGUGUCUUAGCUGGUUau------------------------------------------------------------------- 76 0,-2 ---------------------UGGCAGUGUCUUAGCUGGUUu-------------------------------------------------------------------- 124 0,-2 ---------------------UGGCAGUGUCUUAGCUGGUUuu------------------------------------------------------------------- 100 0,-2 ---------------------UGGCAGUGUCUUAGCUGGUUG-------------------------------------------------------------------- 2560 0,-1 ---------------------UGGCAGUGUCUUAGCUGGUUGa------------------------------------------------------------------- 1854 0,-1 ---------------------UGGCAGUGUCUUAGCUGGUUGaa------------------------------------------------------------------ 470 0,-1 ---------------------UGGCAGUGUCUUAGCUGGUUGau------------------------------------------------------------------ 88 0,-1 ---------------------UGGCAGUGUCUUAGCUGGUUGc------------------------------------------------------------------- 70 0,-1 ---------------------UGGCAGUGUCUUAGCUGGUUGg------------------------------------------------------------------- 31 0,-1 ---------------------UGGCAGUGUCUUAGCUGGUUGU------------------------------------------------------------------- 22357 0,0 ---------------------UGGCAGUGUCUUAGCUGGUUGUa------------------------------------------------------------------ 1689 0,0 ---------------------UGGCAGUGUCUUAGCUGGUUGUaa----------------------------------------------------------------- 836 0,0 ---------------------UGGCAGUGUCUUAGCUGGUUGUau----------------------------------------------------------------- 475 0,0 ---------------------UGGCAGUGUCUUAGCUGGUUGUc------------------------------------------------------------------ 31 0,0 ---------------------UGGCAGUGUCUUAGCUGGUUGUg------------------------------------------------------------------ 28 0,0 ---------------------UGGCAGUGUCUUAGCUGGUUGUU------------------------------------------------------------------ 17153 0,1 ---------------------UGGCAGUGUCUUAGCUGGUUGUUa----------------------------------------------------------------- 921 0,1 ---------------------UGGCAGUGUCUUAGCUGGUUGUUaa---------------------------------------------------------------- 92 0,1 ---------------------UGGCAGUGUCUUAGCUGGUUGUUau---------------------------------------------------------------- 89 0,1 ---------------------UGGCAGUGUCUUAGCUGGUUGUUc----------------------------------------------------------------- 15 0,1 ---------------------UGGCAGUGUCUUAGCUGGUUGUUu----------------------------------------------------------------- 2448 0,1 ---------------------UGGCAGUGUCUUAGCUGGUUGUUuu---------------------------------------------------------------- 95 0,1 ---------------------UGGCAGUGUCUUAGCUGGUUGUUG----------------------------------------------------------------- 107 0,2 ---------------------UGGCAGUGUCUUAGCUGGUUGUUGa---------------------------------------------------------------- 4 0,2 ---------------------UGGCAGUGUCUUAGCUGGUUGUUGU---------------------------------------------------------------- 7 0,3 ----------------------GGCAGUGUCUUAGCUGGUU--------------------------------------------------------------------- 17 1,-2 ----------------------GGCAGUGUCUUAGCUGGUUuu------------------------------------------------------------------- 5 1,-2 ----------------------GGCAGUGUCUUAGCUGGUUG-------------------------------------------------------------------- 26 1,-1 ----------------------GGCAGUGUCUUAGCUGGUUGa------------------------------------------------------------------- 17 1,-1 ----------------------GGCAGUGUCUUAGCUGGUUGaa------------------------------------------------------------------ 4 1,-1 ----------------------GGCAGUGUCUUAGCUGGUUGU------------------------------------------------------------------- 566 1,0 ----------------------GGCAGUGUCUUAGCUGGUUGUa------------------------------------------------------------------ 35 1,0 ----------------------GGCAGUGUCUUAGCUGGUUGUaa----------------------------------------------------------------- 19 1,0 ----------------------GGCAGUGUCUUAGCUGGUUGUau----------------------------------------------------------------- 7 1,0 ----------------------GGCAGUGUCUUAGCUGGUUGUU------------------------------------------------------------------ 616 1,1 ----------------------GGCAGUGUCUUAGCUGGUUGUUa----------------------------------------------------------------- 15 1,1 ----------------------GGCAGUGUCUUAGCUGGUUGUUu----------------------------------------------------------------- 60 1,1 ----------------------GGCAGUGUCUUAGCUGGUUGUUG----------------------------------------------------------------- 2 1,2 -----------------------GCAGUGUCUUAGCUGGUUGU------------------------------------------------------------------- 5 2,0 -----------------------GCAGUGUCUUAGCUGGUUGUU------------------------------------------------------------------ 4 2,1 ---------------------------------------------------------------CAAUCAGCAAGUAUACUG----------------------------- 2 0,-4 ---------------------------------------------------------------CAAUCAGCAAGUAUACUGCC--------------------------- 24 0,-2 ---------------------------------------------------------------CAAUCAGCAAGUAUACUGCCC-------------------------- 15 0,-1 ---------------------------------------------------------------CAAUCAGCAAGUAUACUGCCCU------------------------- 76 0,0 ---------------------------------------------------------------CAAUCAGCAAGUAUACUGCCCUu------------------------ 132 0,0 ---------------------------------------------------------------CAAUCAGCAAGUAUACUGCCCUuu----------------------- 30 0,0 ---------------------------------------------------------------CAAUCAGCAAGUAUACUGCCCUA------------------------ 98 0,1 ---------------------------------------------------------------CAAUCAGCAAGUAUACUGCCCUAa----------------------- 4 0,1 ---------------------------------------------------------------CAAUCAGCAAGUAUACUGCCCUAu----------------------- 37 0,1 ----------------------------------------------------------------AAUCAGCAAGUAUACUGCCC-------------------------- 2 1,-1 ----------------------------------------------------------------AAUCAGCAAGUAUACUGCCCU------------------------- 40 1,0 ----------------------------------------------------------------AAUCAGCAAGUAUACUGCCCUu------------------------ 40 1,0 ----------------------------------------------------------------AAUCAGCAAGUAUACUGCCCUuu----------------------- 4 1,0 ----------------------------------------------------------------AAUCAGCAAGUAUACUGCCCUA------------------------ 281 1,1 ----------------------------------------------------------------AAUCAGCAAGUAUACUGCCCUAa----------------------- 30 1,1 ----------------------------------------------------------------AAUCAGCAAGUAUACUGCCCUAau---------------------- 2 1,1 ----------------------------------------------------------------AAUCAGCAAGUAUACUGCCCUAu----------------------- 86 1,1 -----------------------------------------------------------------AUCAGCAAGUAUACUGCCCUAG----------------------- 3 2,2 -----------------------------------------------------------------AUCAGCAAGUAUACUGCCCUAGu---------------------- 3 2,2 >hsa-mir-34b mi:13-35;MA:50-71 Tumor gugcucgguuugUAGGCAGUGUCAUUAGCUGAUUGuacuguggugguuaCAAUCACUAACUCCACUGCCAUcaaaacaaggcac ------------UAGGCAGUGUCAUUAGCUGAUU-------------------------------------------------- 3 0,-1 ------------UAGGCAGUGUCAUUAGCUGAUUG------------------------------------------------- 4 0,0 ------------UAGGCAGUGUCAUUAGCUGAUUGU------------------------------------------------ 3 0,1 -------------AGGCAGUGUCAUUAGCUG----------------------------------------------------- 2 1,-4 -------------AGGCAGUGUCAUUAGCUGAUU-------------------------------------------------- 33 1,-1 -------------AGGCAGUGUCAUUAGCUGAUUuu------------------------------------------------ 2 1,-1 -------------AGGCAGUGUCAUUAGCUGAUUG------------------------------------------------- 110 1,0 -------------AGGCAGUGUCAUUAGCUGAUUGa------------------------------------------------ 24 1,0 -------------AGGCAGUGUCAUUAGCUGAUUGU------------------------------------------------ 675 1,1 -------------AGGCAGUGUCAUUAGCUGAUUGUu----------------------------------------------- 2 1,1 -------------AGGCAGUGUCAUUAGCUGAUUGUA----------------------------------------------- 49 1,2 -------------AGGCAGUGUCAUUAGCUGAUUGUAa---------------------------------------------- 2 1,2 -------------AGGCAGUGUCAUUAGCUGAUUGUAu---------------------------------------------- 2 1,2 -------------------------------------------------CAAUCACUAACUCCACUGCCAUC------------ 3 0,1 -------------------------------------------------CAAUCACUAACUCCACUGCCAUCu----------- 2 0,1 --------------------------------------------------AAUCACUAACUCCACUGCCA-------------- 2 1,-1 --------------------------------------------------AAUCACUAACUCCACUGCCAU------------- 2 1,0 --------------------------------------------------AAUCACUAACUCCACUGCCAUC------------ 43 1,1 --------------------------------------------------AAUCACUAACUCCACUGCCAUCu----------- 4 1,1 ---------------------------------------------------AUCACUAACUCCACUGCCAUC------------ 4 2,1 >hsa-mir-34c 5p:13-35;3p:46-67 Tumor agucuaguuacuAGGCAGUGUAGUUAGCUGAUUGCuaauaguaccAAUCACUAACCACACGGCCAGGuaaaaagauu ----------CUAGGCAGUGUAGUUAGCUGAU--------------------------------------------- 2 -2,-3 ----------CUAGGCAGUGUAGUUAGCUGAUU-------------------------------------------- 3 -2,-2 -----------UAGGCAGUGUAGUUAGCUGAU--------------------------------------------- 2 -1,-3 -----------UAGGCAGUGUAGUUAGCUGAUU-------------------------------------------- 15 -1,-2 -----------UAGGCAGUGUAGUUAGCUGAUUG------------------------------------------- 4 -1,-1 -----------UAGGCAGUGUAGUUAGCUGAUUGu------------------------------------------ 11 -1,-1 ------------AGGCAGUGUAGUUAGCUG----------------------------------------------- 3 0,-5 ------------AGGCAGUGUAGUUAGCUGA---------------------------------------------- 6 0,-4 ------------AGGCAGUGUAGUUAGCUGAU--------------------------------------------- 135 0,-3 ------------AGGCAGUGUAGUUAGCUGAUa-------------------------------------------- 10 0,-3 ------------AGGCAGUGUAGUUAGCUGAUU-------------------------------------------- 647 0,-2 ------------AGGCAGUGUAGUUAGCUGAUUa------------------------------------------- 2 0,-2 ------------AGGCAGUGUAGUUAGCUGAUUau------------------------------------------ 2 0,-2 ------------AGGCAGUGUAGUUAGCUGAUUu------------------------------------------- 7 0,-2 ------------AGGCAGUGUAGUUAGCUGAUUG------------------------------------------- 491 0,-1 ------------AGGCAGUGUAGUUAGCUGAUUGa------------------------------------------ 213 0,-1 ------------AGGCAGUGUAGUUAGCUGAUUGg------------------------------------------ 2 0,-1 ------------AGGCAGUGUAGUUAGCUGAUUGu------------------------------------------ 174 0,-1 ------------AGGCAGUGUAGUUAGCUGAUUGC------------------------------------------ 2946 0,0 ------------AGGCAGUGUAGUUAGCUGAUUGCa----------------------------------------- 56 0,0 ------------AGGCAGUGUAGUUAGCUGAUUGCc----------------------------------------- 2 0,0 ------------AGGCAGUGUAGUUAGCUGAUUGCU----------------------------------------- 43 0,1 -------------GGCAGUGUAGUUAGCUGAUUGC------------------------------------------ 7 1,0 ---------------------------------------------AAUCACUAACCACACGGCCAa----------- 2 0,-2 ---------------------------------------------AAUCACUAACCACACGGCCAG----------- 5 0,-1 ---------------------------------------------AAUCACUAACCACACGGCCAGu---------- 5 0,-1 ---------------------------------------------AAUCACUAACCACACGGCCAGG---------- 31 0,0 ---------------------------------------------AAUCACUAACCACACGGCCAGGa--------- 2 0,0 ----------------------------------------------AUCACUAACCACACGGCCAGG---------- 2 1,0 >hsa-mir-3545 5p:15-36;3p:54-76 Tumor gcgcccgccgggucUAGUGGUCCUAAACAUUUCACAauugcgcuacagaacugUUGAACUGUUAAGAACCACUGGAcccagcgcgc -----------------------------------------------------UUGAACUGUUAAGAACCACUGu----------- 2 0,-2 -----------------------------------------------------UUGAACUGUUAAGAACCACUGG----------- 48 0,-1 -----------------------------------------------------UUGAACUGUUAAGAACCACUGGu---------- 23 0,-1 -----------------------------------------------------UUGAACUGUUAAGAACCACUGGA---------- 10 0,0 ------------------------------------------------------UGAACUGUUAAGAACCACUGG----------- 2 1,-1 >hsa-mir-3605 5p:22-44;3p:66-88 Tumor acuuuauacguguaauugugaUGAGGAUGGAUAGCAAGGAAGCCgcucccaccugacccucacggCCUCCGUGUUACCUGUCCUCUAGgugggacgcucg ---------------------UGAGGAUGGAUAGCAAGGAAG---------------------------------------------------------- 5 0,-2 -----------------------------------------------------------------CCUCCGUGUUACCUGUCCUCU-------------- 24 0,-2 -----------------------------------------------------------------CCUCCGUGUUACCUGUCCUCUAu------------ 4 0,-1 -----------------------------------------------------------------CCUCCGUGUUACCUGUCCUCUAG------------ 3 0,0 ------------------------------------------------------------------CUCCGUGUUACCUGUCCUCU-------------- 2 1,-2 >hsa-mir-3606 5pM:16-36 Tumor uuguugcuaucuaggUUAGUGAAGGCUAUUUUAAUUuuuuuaaaauuucuuucacuacuuagg ---------------UUAGUGAAGGCUAUUUUAAUUUU------------------------- 2 0,2 >hsa-mir-3607 5p:12-33;3p:51-70 Tumor aagguugcgguGCAUGUGAUGAAGCAAAUCAGUaugaaugaauucaugauACUGUAAACGCUUUCUGAUGuacuacuca -----------GCAUGUGAUGAAGCAAAU-------------------------------------------------- 2 0,-4 ------------------------------------------------AUACUGUAAACGCUUUCUGAUG--------- 38 -2,0 -------------------------------------------------UACUGUAAACGCUUUCUGAUG--------- 8 -1,0 --------------------------------------------------ACUGUAAACGCUUUCUGAUG--------- 42 0,0 ---------------------------------------------------CUGUAAACGCUUUCUGAUG--------- 202 1,0 ----------------------------------------------------UGUAAACGCUUUCUGAUG--------- 21 2,0 >hsa-mir-361 5p:6-27;3p:45-67 Tumor ggagcUUAUCAGAAUCUCCAGGGGUACuuuauaauuucaaaaagUCCCCCAGGUGUGAUUCUGAUUUgcuuc ----CUUAUCAGAAUCUCCAGGGGU----------------------------------------------- 2 -1,-2 ----CUUAUCAGAAUCUCCAGGGGUAa--------------------------------------------- 4 -1,-1 ----CUUAUCAGAAUCUCCAGGGGUAu--------------------------------------------- 5 -1,-1 ----CUUAUCAGAAUCUCCAGGGGUAC--------------------------------------------- 13 -1,0 -----UUAUCAGAAUCUCCAGGG------------------------------------------------- 12 0,-4 -----UUAUCAGAAUCUCCAGGGa------------------------------------------------ 4 0,-4 -----UUAUCAGAAUCUCCAGGGG------------------------------------------------ 110 0,-3 -----UUAUCAGAAUCUCCAGGGGa----------------------------------------------- 7 0,-3 -----UUAUCAGAAUCUCCAGGGGaa---------------------------------------------- 5 0,-3 -----UUAUCAGAAUCUCCAGGGGU----------------------------------------------- 645 0,-2 -----UUAUCAGAAUCUCCAGGGGUc---------------------------------------------- 4 0,-2 -----UUAUCAGAAUCUCCAGGGGUu---------------------------------------------- 25 0,-2 -----UUAUCAGAAUCUCCAGGGGUuu--------------------------------------------- 9 0,-2 -----UUAUCAGAAUCUCCAGGGGUA---------------------------------------------- 1575 0,-1 -----UUAUCAGAAUCUCCAGGGGUAa--------------------------------------------- 1709 0,-1 -----UUAUCAGAAUCUCCAGGGGUAaa-------------------------------------------- 346 0,-1 -----UUAUCAGAAUCUCCAGGGGUAau-------------------------------------------- 131 0,-1 -----UUAUCAGAAUCUCCAGGGGUAg--------------------------------------------- 75 0,-1 -----UUAUCAGAAUCUCCAGGGGUAu--------------------------------------------- 2006 0,-1 -----UUAUCAGAAUCUCCAGGGGUAuu-------------------------------------------- 86 0,-1 -----UUAUCAGAAUCUCCAGGGGUAC--------------------------------------------- 8555 0,0 -----UUAUCAGAAUCUCCAGGGGUACa-------------------------------------------- 964 0,0 -----UUAUCAGAAUCUCCAGGGGUACaa------------------------------------------- 39 0,0 -----UUAUCAGAAUCUCCAGGGGUACau------------------------------------------- 19 0,0 -----UUAUCAGAAUCUCCAGGGGUACc-------------------------------------------- 81 0,0 -----UUAUCAGAAUCUCCAGGGGUACg-------------------------------------------- 29 0,0 -----UUAUCAGAAUCUCCAGGGGUACU-------------------------------------------- 1059 0,1 -----UUAUCAGAAUCUCCAGGGGUACUa------------------------------------------- 10 0,1 -----UUAUCAGAAUCUCCAGGGGUACUU------------------------------------------- 7 0,2 -----UUAUCAGAAUCUCCAGGGGUACUUU------------------------------------------ 2 0,3 ------UAUCAGAAUCUCCAGGGGUA---------------------------------------------- 8 1,-1 ------UAUCAGAAUCUCCAGGGGUAa--------------------------------------------- 26 1,-1 ------UAUCAGAAUCUCCAGGGGUAau-------------------------------------------- 2 1,-1 ------UAUCAGAAUCUCCAGGGGUAu--------------------------------------------- 24 1,-1 ------UAUCAGAAUCUCCAGGGGUAC--------------------------------------------- 132 1,0 ------UAUCAGAAUCUCCAGGGGUACa-------------------------------------------- 7 1,0 ------UAUCAGAAUCUCCAGGGGUACU-------------------------------------------- 19 1,1 ------------------------------------------AGUCCCCCAGGUGUGAUUCUGA-------- 7 -2,-3 ------------------------------------------AGUCCCCCAGGUGUGAUUCUGAU------- 21 -2,-2 ------------------------------------------AGUCCCCCAGGUGUGAUUCUGAUU------ 11 -2,-1 ------------------------------------------AGUCCCCCAGGUGUGAUUCUGAUUU----- 4 -2,0 -------------------------------------------GUCCCCCAGGUGUGAUUCUGA-------- 2 -1,-3 -------------------------------------------GUCCCCCAGGUGUGAUUCUGAU------- 12 -1,-2 -------------------------------------------GUCCCCCAGGUGUGAUUCUGAUU------ 4 -1,-1 -------------------------------------------GUCCCCCAGGUGUGAUUCUGAUUU----- 2 -1,0 --------------------------------------------UCCCCCAGGUGUGAUUCU---------- 2 0,-5 --------------------------------------------UCCCCCAGGUGUGAUUCUG--------- 20 0,-4 --------------------------------------------UCCCCCAGGUGUGAUUCUGA-------- 389 0,-3 --------------------------------------------UCCCCCAGGUGUGAUUCUGAa------- 18 0,-3 --------------------------------------------UCCCCCAGGUGUGAUUCUGAaa------ 60 0,-3 --------------------------------------------UCCCCCAGGUGUGAUUCUGAU------- 1141 0,-2 --------------------------------------------UCCCCCAGGUGUGAUUCUGAUa------ 243 0,-2 --------------------------------------------UCCCCCAGGUGUGAUUCUGAUaa----- 35 0,-2 --------------------------------------------UCCCCCAGGUGUGAUUCUGAUau----- 2 0,-2 --------------------------------------------UCCCCCAGGUGUGAUUCUGAUg------ 8 0,-2 --------------------------------------------UCCCCCAGGUGUGAUUCUGAUU------ 2625 0,-1 --------------------------------------------UCCCCCAGGUGUGAUUCUGAUUa----- 25 0,-1 --------------------------------------------UCCCCCAGGUGUGAUUCUGAUUU----- 1839 0,0 --------------------------------------------UCCCCCAGGUGUGAUUCUGAUUUu---- 34 0,0 --------------------------------------------UCCCCCAGGUGUGAUUCUGAUUUG---- 576 0,1 --------------------------------------------UCCCCCAGGUGUGAUUCUGAUUUGu--- 27 0,1 --------------------------------------------UCCCCCAGGUGUGAUUCUGAUUUGC--- 6 0,2 ---------------------------------------------CCCCCAGGUGUGAUUCUGAU------- 3 1,-2 ---------------------------------------------CCCCCAGGUGUGAUUCUGAUU------ 24 1,-1 ---------------------------------------------CCCCCAGGUGUGAUUCUGAUUU----- 50 1,0 ---------------------------------------------CCCCCAGGUGUGAUUCUGAUUUa---- 2 1,0 ---------------------------------------------CCCCCAGGUGUGAUUCUGAUUUG---- 120 1,1 ---------------------------------------------CCCCCAGGUGUGAUUCUGAUUUGa--- 4 1,1 ---------------------------------------------CCCCCAGGUGUGAUUCUGAUUUGu--- 15 1,1 ---------------------------------------------CCCCCAGGUGUGAUUCUGAUUUGC--- 113 1,2 ----------------------------------------------CCCCAGGUGUGAUUCUGAU------- 2 2,-2 ----------------------------------------------CCCCAGGUGUGAUUCUGAUU------ 6 2,-1 ----------------------------------------------CCCCAGGUGUGAUUCUGAUUU----- 3 2,0 ----------------------------------------------CCCCAGGUGUGAUUCUGAUUUG---- 2 2,1 >hsa-mir-3611 3pM:52-72 Tumor agcaggucuaauaagaauuucuuuuucuucacaauuaugaaagaaaagaaaUUGUGAAGAAAGAAAUUCUUAcuaguuuugcu ------------AAGAAUUUCUUUUUCUUCACA-------------------------------------------------- 2 ------------AAGAAUUUCUUUUUCUUCACAA------------------------------------------------- 2 ------------AAGAAUUUCUUUUUCUUCACAAU------------------------------------------------ 6 ------------AAGAAUUUCUUUUUCUUCACAAUU----------------------------------------------- 9 ---------------------------------------------------UUGUGAAGAAAGAAAUUCU------------- 8 0,-2 ---------------------------------------------------UUGUGAAGAAAGAAAUUCUU------------ 78 0,-1 ---------------------------------------------------UUGUGAAGAAAGAAAUUCUUA----------- 53 0,0 ---------------------------------------------------UUGUGAAGAAAGAAAUUCUUAa---------- 2 0,0 ---------------------------------------------------UUGUGAAGAAAGAAAUUCUUAC---------- 51 0,1 ---------------------------------------------------UUGUGAAGAAAGAAAUUCUUACa--------- 4 0,1 ---------------------------------------------------UUGUGAAGAAAGAAAUUCUUACU--------- 2 0,2 ----------------------------------------------------UGUGAAGAAAGAAAUUCUUA----------- 2 1,0 ----------------------------------------------------UGUGAAGAAAGAAAUUCUUAC---------- 2 1,1 >hsa-mir-3613 5p:16-37;3p:53-76 Tumor ugguuggguuuggauUGUUGUACUUUUUUUUUUGUUCguugcauuuuuaggaACAAAAAAAAAAGCCCAACCCUUCacaccacuuca --------------UUGUUGUACUUUUUUUUUUGUU--------------------------------------------------- 2 -1,-1 ---------------UGUUGUACUUUUUUUUUU------------------------------------------------------ 169 0,-4 ---------------UGUUGUACUUUUUUUUUUuu---------------------------------------------------- 14 0,-4 ---------------UGUUGUACUUUUUUUUUUG----------------------------------------------------- 26 0,-3 ---------------UGUUGUACUUUUUUUUUUGa---------------------------------------------------- 2 0,-3 ---------------UGUUGUACUUUUUUUUUUGU---------------------------------------------------- 249 0,-2 ---------------UGUUGUACUUUUUUUUUUGUU--------------------------------------------------- 1429 0,-1 ---------------UGUUGUACUUUUUUUUUUGUUa-------------------------------------------------- 59 0,-1 ---------------UGUUGUACUUUUUUUUUUGUUaa------------------------------------------------- 13 0,-1 ---------------UGUUGUACUUUUUUUUUUGUUu-------------------------------------------------- 13 0,-1 ---------------UGUUGUACUUUUUUUUUUGUUC-------------------------------------------------- 890 0,0 ---------------UGUUGUACUUUUUUUUUUGUUCa------------------------------------------------- 34 0,0 ---------------UGUUGUACUUUUUUUUUUGUUCu------------------------------------------------- 7 0,0 ---------------UGUUGUACUUUUUUUUUUGUUCG------------------------------------------------- 10 0,1 ----------------GUUGUACUUUUUUUUUUGUU--------------------------------------------------- 12 1,-1 ----------------GUUGUACUUUUUUUUUUGUUu-------------------------------------------------- 2 1,-1 ----------------GUUGUACUUUUUUUUUUGUUC-------------------------------------------------- 14 1,0 ----------------------------------------------------ACAAAAAAAAAAGCCCAACC--------------- 11 0,-4 ----------------------------------------------------ACAAAAAAAAAAGCCCAACCCU------------- 106 0,-2 ----------------------------------------------------ACAAAAAAAAAAGCCCAACCCUa------------ 2 0,-2 ----------------------------------------------------ACAAAAAAAAAAGCCCAACCCUU------------ 4 0,-1 >hsa-mir-3614 5p:15-37;3p:53-75 Tumor gguucugucuugggCCACUUGGAUCUGAAGGCUGCCCcuuugcucucuggggUAGCCUUCAGAUCUUGGUGUUUUgaauucuuacu --------------CCACUUGGAUCUGAAGGCU----------------------------------------------------- 2 0,-4 --------------CCACUUGGAUCUGAAGGCUGa--------------------------------------------------- 2 0,-3 --------------CCACUUGGAUCUGAAGGCUGC--------------------------------------------------- 6 0,-2 --------------CCACUUGGAUCUGAAGGCUGCC-------------------------------------------------- 34 0,-1 ----------------------------------------------------UAGCCUUCAGAUCUUGGUGU-------------- 6 0,-3 ----------------------------------------------------UAGCCUUCAGAUCUUGGUGUU------------- 23 0,-2 ----------------------------------------------------UAGCCUUCAGAUCUUGGUGUUa------------ 2 0,-2 ----------------------------------------------------UAGCCUUCAGAUCUUGGUGUUU------------ 14 0,-1 ----------------------------------------------------UAGCCUUCAGAUCUUGGUGUUUU----------- 2 0,0 >hsa-mir-3615 3pM:51-71 Tumor gacucugggacgcucagacgccgcgcggggcggggauuggucugugguccUCUCUCGGCUCCUCGCGGCUCgcggcggccgacgguu --------------------------------------------------UCUCUCGGCUCCUCGCGG------------------- 7 0,-3 --------------------------------------------------UCUCUCGGCUCCUCGCGGa------------------ 5 0,-3 --------------------------------------------------UCUCUCGGCUCCUCGCGGC------------------ 10 0,-2 --------------------------------------------------UCUCUCGGCUCCUCGCGGCU----------------- 116 0,-1 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUu---------------- 6 0,-1 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUuu--------------- 18 0,-1 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUC---------------- 13 0,0 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUCc--------------- 2 0,0 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUCu--------------- 19 0,0 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUCuu-------------- 3 0,0 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUCG--------------- 53 0,1 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUCGa-------------- 14 0,1 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUCGu-------------- 34 0,1 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUCGuu------------- 16 0,1 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUCGC-------------- 31 0,2 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUCGCu------------- 2 0,2 --------------------------------------------------UCUCUCGGCUCCUCGCGGCUCGCuu------------ 2 0,2 >hsa-mir-3616 5p:19-40;3p:60-82 Tumor ugucacuccgccagcaucAUGAAGUGCACUCAUGAUAUGUuugccccaucagcgugucaCGAGGGCAUUUCAUGAUGCAGGCgggguuggca -----------------------------------------------------------CGAGGGCAUUUCAUGAUGCAGG----------- 2 0,-1 >hsa-mir-3617 5pM:10-31 Tumor aggucauagAAAGACAUAGUUGCAAGAUGGGauuagaaaccauaugucucaucagcacccuauguccuuucucugcccu ---------AAAGACAUAGUUGCAAGAUG-------------------------------------------------- 2 0,-2 ---------AAAGACAUAGUUGCAAGAUGGG------------------------------------------------ 10 0,0 ---------AAAGACAUAGUUGCAAGAUGGGA----------------------------------------------- 10 0,1 >hsa-mir-3619 5p:16-37;3p:47-68 Tumor acggcaucuuugcacUCAGCAGGCAGGCUGGUGCAGCccgugguggGGGACCAUCCUGCCUGCUGUGGgguaaggacggcugu ----------------------------------------------GGGACCAUCCUGCCUGCUGUGGa-------------- 2 0,0 >hsa-mir-362 5p:5-28;3p:42-63 Tumor cuugAAUCCUUGGAACCUAGGUGUGAGUgcuauuucagugcAACACACCUAUUCAAGGAUUCAaa ----AAUCCUUGGAACCUAGGUG------------------------------------------ 2 0,-5 ----AAUCCUUGGAACCUAGGUGU----------------------------------------- 19 0,-4 ----AAUCCUUGGAACCUAGGUGUG---------------------------------------- 37 0,-3 ----AAUCCUUGGAACCUAGGUGUGu--------------------------------------- 7 0,-3 ----AAUCCUUGGAACCUAGGUGUGA--------------------------------------- 515 0,-2 ----AAUCCUUGGAACCUAGGUGUGAa-------------------------------------- 45 0,-2 ----AAUCCUUGGAACCUAGGUGUGAaa------------------------------------- 2 0,-2 ----AAUCCUUGGAACCUAGGUGUGAu-------------------------------------- 6 0,-2 ----AAUCCUUGGAACCUAGGUGUGAuu------------------------------------- 2 0,-2 ----AAUCCUUGGAACCUAGGUGUGAG-------------------------------------- 1071 0,-1 ----AAUCCUUGGAACCUAGGUGUGAGa------------------------------------- 231 0,-1 ----AAUCCUUGGAACCUAGGUGUGAGaa------------------------------------ 4 0,-1 ----AAUCCUUGGAACCUAGGUGUGAGau------------------------------------ 2 0,-1 ----AAUCCUUGGAACCUAGGUGUGAGc------------------------------------- 2 0,-1 ----AAUCCUUGGAACCUAGGUGUGAGU------------------------------------- 1917 0,0 ----AAUCCUUGGAACCUAGGUGUGAGUu------------------------------------ 5 0,0 ----AAUCCUUGGAACCUAGGUGUGAGUG------------------------------------ 19 0,1 -----AUCCUUGGAACCUAGGUGUGA--------------------------------------- 2 1,-2 -----AUCCUUGGAACCUAGGUGUGAGU------------------------------------- 8 1,0 -----------------------------------------AACACACCUAUUCAAGGA------ 3 0,-4 -----------------------------------------AACACACCUAUUCAAGGAa----- 2 0,-4 -----------------------------------------AACACACCUAUUCAAGGAU----- 72 0,-3 -----------------------------------------AACACACCUAUUCAAGGAUa---- 5 0,-3 -----------------------------------------AACACACCUAUUCAAGGAUU---- 789 0,-2 -----------------------------------------AACACACCUAUUCAAGGAUUa--- 2 0,-2 -----------------------------------------AACACACCUAUUCAAGGAUUu--- 4 0,-2 -----------------------------------------AACACACCUAUUCAAGGAUUC--- 274 0,-1 -----------------------------------------AACACACCUAUUCAAGGAUUCu-- 48 0,-1 -----------------------------------------AACACACCUAUUCAAGGAUUCA-- 1363 0,0 -----------------------------------------AACACACCUAUUCAAGGAUUCAA- 74 0,1 ------------------------------------------ACACACCUAUUCAAGGAU----- 2 1,-3 ------------------------------------------ACACACCUAUUCAAGGAUU---- 5 1,-2 ------------------------------------------ACACACCUAUUCAAGGAUUCA-- 32 1,0 >hsa-mir-3620 3pM:58-79 Tumor gugaggugggggccagcagggagugggcugggcugggcugggccaagguacaaggccUCACCCUGCAUCCCGCACCCAG ---------------------------------------------------------UCACCCUGCAUCCCGCACCCAGu 7 0,0 ----------------------------------------------------------CACCCUGCAUCCCGCACCCAGu 2 1,0 >hsa-mir-363 mi:7-28;MA:50-71 Tumor uguuguCGGGUGGAUCACGAUGCAAUUUugaugaguaucauaggagaaaAAUUGCACGGUAUCCAUCUGUAaacc ------CGGGUGGAUCACGAUGCAAUUU----------------------------------------------- 5 0,0 ------CGGGUGGAUCACGAUGCAAUUUU---------------------------------------------- 10 0,1 -------------------------------------------------AAUUGCACGGUAUCCAUC-------- 4 0,-4 -------------------------------------------------AAUUGCACGGUAUCCAUCU------- 24 0,-3 -------------------------------------------------AAUUGCACGGUAUCCAUCUau----- 4 0,-3 -------------------------------------------------AAUUGCACGGUAUCCAUCUuu----- 4 0,-3 -------------------------------------------------AAUUGCACGGUAUCCAUCUG------ 157 0,-2 -------------------------------------------------AAUUGCACGGUAUCCAUCUGa----- 65 0,-2 -------------------------------------------------AAUUGCACGGUAUCCAUCUGaa---- 2 0,-2 -------------------------------------------------AAUUGCACGGUAUCCAUCUGc----- 2 0,-2 -------------------------------------------------AAUUGCACGGUAUCCAUCUGU----- 4060 0,-1 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUc---- 6 0,-1 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUu---- 179 0,-1 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUuu--- 56 0,-1 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUA---- 4823 0,0 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUAc--- 10 0,0 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUAg--- 49 0,0 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUAu--- 1399 0,0 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUAuu-- 15 0,0 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUAA--- 2046 0,1 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUAAu-- 19 0,1 -------------------------------------------------AAUUGCACGGUAUCCAUCUGUAAA-- 29 0,2 --------------------------------------------------AUUGCACGGUAUCCAUCUGa----- 2 1,-2 --------------------------------------------------AUUGCACGGUAUCCAUCUGU----- 443 1,-1 --------------------------------------------------AUUGCACGGUAUCCAUCUGUu---- 9 1,-1 --------------------------------------------------AUUGCACGGUAUCCAUCUGUuu--- 11 1,-1 --------------------------------------------------AUUGCACGGUAUCCAUCUGUA---- 469 1,0 --------------------------------------------------AUUGCACGGUAUCCAUCUGUAc--- 3 1,0 --------------------------------------------------AUUGCACGGUAUCCAUCUGUAg--- 4 1,0 --------------------------------------------------AUUGCACGGUAUCCAUCUGUAu--- 347 1,0 --------------------------------------------------AUUGCACGGUAUCCAUCUGUAuu-- 70 1,0 --------------------------------------------------AUUGCACGGUAUCCAUCUGUAA--- 406 1,1 --------------------------------------------------AUUGCACGGUAUCCAUCUGUAAu-- 4 1,1 --------------------------------------------------AUUGCACGGUAUCCAUCUGUAAA-- 17 1,2 ---------------------------------------------------UUGCACGGUAUCCAUCUGUAA--- 4 2,1 >hsa-mir-3647 5p:15-37;3p:62-84 Tumor uugcuuucaucagcCUGAAGUGAUGAUUCACAUUCAUgucucuucucugauaaauucuugaAGAAAAUUUUUGUGUGUCUGAUCaggccucuagagggcag --------------CUGAAGUGAUGAUUCACAUU------------------------------------------------------------------- 2 0,-3 ---------------UGAAGUGAUGAUUCACAUUC------------------------------------------------------------------ 2 1,-2 ---------------------------------------------------------------AAAAUUUUUGUGUGUCUGAUC----------------- 5 2,0 >hsa-mir-3648 5pM:28-48 Tumor cgcgacugcggcggcggugguggggggAGCCGCGGGGAUCGCCGAGGGccggucggccgccccgggugccgcgcggugccgccggcggcggugaggccccgcgcgugugucccggcugcggucggccgcgcucgagggguccccguggcguccccuuccccgccggccgccuuucucgcg ---------------------------------------------------------------------CGCGCGGUGCCGCCGGCG--------------------------------------------------------------------------------------------- 3 ---------------------------------------------------------------------CGCGCGGUGCCGCCGGCGG-------------------------------------------------------------------------------------------- 5 ---------------------------------------------------------------------CGCGCGGUGCCGCCGGCGGC------------------------------------------------------------------------------------------- 4 ----------------------------------------------------------------------GCGCGGUGCCGCCGGCGG-------------------------------------------------------------------------------------------- 12 -----------------------------------------------------------------------------------------------GCCCCGCGCGUGUGUCCCGG----------------------------------------------------------------- 5 -----------------------------------------------------------------------------------------------GCCCCGCGCGUGUGUCCCGGC---------------------------------------------------------------- 8 -------------------------------------------------------------------------------------------------CCCGCGCGUGUGUCCCGGC---------------------------------------------------------------- 2 --------------------------------------------------------------------------------------------------CCGCGCGUGUGUCCCGGC---------------------------------------------------------------- 5 -----------------------------------------------------------------------------------------------------CGCGUGUGUCCCGGCUGCG------------------------------------------------------------ 3 ---------------------------------------------------------------------------------------------------------------------------GGCCGCGCUCGAGGGGUCCCCG----------------------------------- 2 --------------------------------------------------------------------------------------------------------------------------------CGCUCGAGGGGUCCCCGUGGCG------------------------------ 3 ---------------------------------------------------------------------------------------------------------------------------------GCUCGAGGGGUCCCCGUG--------------------------------- 2 ---------------------------------------------------------------------------------------------------------------------------------GCUCGAGGGGUCCCCGUGGC------------------------------- 2 ---------------------------------------------------------------------------------------------------------------------------------GCUCGAGGGGUCCCCGUGGCG------------------------------ 2 ----------------------------------------------------------------------------------------------------------------------------------CUCGAGGGGUCCCCGUGGC------------------------------- 4 ----------------------------------------------------------------------------------------------------------------------------------CUCGAGGGGUCCCCGUGGCGUCCC-------------------------- 2 ----------------------------------------------------------------------------------------------------------------------------------CUCGAGGGGUCCCCGUGGCGUCCCC------------------------- 2 ------------------------------------------------------------------------------------------------------------------------------------CGAGGGGUCCCCGUGGCG------------------------------ 2 --------------------------------------------------------------------------------------------------------------------------------------AGGGGUCCCCGUGGCGUCC--------------------------- 2 --------------------------------------------------------------------------------------------------------------------------------------AGGGGUCCCCGUGGCGUCCC-------------------------- 3 --------------------------------------------------------------------------------------------------------------------------------------AGGGGUCCCCGUGGCGUCCCC------------------------- 2 -----------------------------------------------------------------------------------------------------------------------------------------GGUCCCCGUGGCGUCCCC------------------------- 2 ------------------------------------------------------------------------------------------------------------------------------------------GUCCCCGUGGCGUCCCCU------------------------ 3 ------------------------------------------------------------------------------------------------------------------------------------------GUCCCCGUGGCGUCCCCUUCCCCGC----------------- 2 --------------------------------------------------------------------------------------------------------------------------------------------CCCCGUGGCGUCCCCUUCCCCGCC---------------- 2 ----------------------------------------------------------------------------------------------------------------------------------------------CCGUGGCGUCCCCUUCCCCG------------------ 3 -----------------------------------------------------------------------------------------------------------------------------------------------CGUGGCGUCCCCUUCCCCG------------------ 2 -----------------------------------------------------------------------------------------------------------------------------------------------CGUGGCGUCCCCUUCCCCGC----------------- 3 -----------------------------------------------------------------------------------------------------------------------------------------------CGUGGCGUCCCCUUCCCCGCC---------------- 2 ------------------------------------------------------------------------------------------------------------------------------------------------GUGGCGUCCCCUUCCCCGC----------------- 4 ------------------------------------------------------------------------------------------------------------------------------------------------GUGGCGUCCCCUUCCCCGCCG--------------- 2 -------------------------------------------------------------------------------------------------------------------------------------------------UGGCGUCCCCUUCCCCGC----------------- 4 -------------------------------------------------------------------------------------------------------------------------------------------------UGGCGUCCCCUUCCCCGCC---------------- 3 -------------------------------------------------------------------------------------------------------------------------------------------------UGGCGUCCCCUUCCCCGCCG--------------- 15 -------------------------------------------------------------------------------------------------------------------------------------------------UGGCGUCCCCUUCCCCGCCGG-------------- 6 -------------------------------------------------------------------------------------------------------------------------------------------------UGGCGUCCCCUUCCCCGCCGGC------------- 10 -------------------------------------------------------------------------------------------------------------------------------------------------UGGCGUCCCCUUCCCCGCCGGCC------------ 5 -------------------------------------------------------------------------------------------------------------------------------------------------UGGCGUCCCCUUCCCCGCCGGCCG----------- 6 -------------------------------------------------------------------------------------------------------------------------------------------------UGGCGUCCCCUUCCCCGCCGGCCGC---------- 9 ---------------------------------------------------------------------------------------------------------------------------------------------------GCGUCCCCUUCCCCGCCGGC------------- 2 ---------------------------------------------------------------------------------------------------------------------------------------------------GCGUCCCCUUCCCCGCCGGCCG----------- 6 ---------------------------------------------------------------------------------------------------------------------------------------------------GCGUCCCCUUCCCCGCCGGCCGC---------- 2 -----------------------------------------------------------------------------------------------------------------------------------------------------GUCCCCUUCCCCGCCGGCCG----------- 2 -----------------------------------------------------------------------------------------------------------------------------------------------------GUCCCCUUCCCCGCCGGCCGC---------- 3 ------------------------------------------------------------------------------------------------------------------------------------------------------UCCCCUUCCCCGCCGGCC------------ 2 ------------------------------------------------------------------------------------------------------------------------------------------------------UCCCCUUCCCCGCCGGCCG----------- 7 ------------------------------------------------------------------------------------------------------------------------------------------------------UCCCCUUCCCCGCCGGCCGC---------- 19 ------------------------------------------------------------------------------------------------------------------------------------------------------UCCCCUUCCCCGCCGGCCGCC--------- 3 --------------------------------------------------------------------------------------------------------------------------------------------------------CCCUUCCCCGCCGGCCGC---------- 2 >hsa-mir-365-1 3pM:56-77 Tumor accgcagggaaaaugagggacuuuugggggcagauguguuuccauuccacuaucaUAAUGCCCCUAAAAAUCCUUAUugcucuugca ---------------AGGGACUUUUGGGGGCAGAUGU-------------------------------------------------- 12 ---------------AGGGACUUUUGGGGGCAGAUGUG------------------------------------------------- 45 ---------------AGGGACUUUUGGGGGCAGAUGUGU------------------------------------------------ 8 ----------------GGGACUUUUGGGGGCAGAUuu-------------------------------------------------- 2 ----------------GGGACUUUUGGGGGCAGAUGUG------------------------------------------------- 2 -------------------------------------------------------UAAUGCCCCUAAAAAUCC-------------- 2 0,-4 -------------------------------------------------------UAAUGCCCCUAAAAAUCCU------------- 90 0,-3 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUa------------ 4 0,-3 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUU------------ 1090 0,-2 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUc----------- 2 0,-2 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUu----------- 153 0,-2 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUuu---------- 214 0,-2 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUA----------- 1486 0,-1 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAa---------- 165 0,-1 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAaa--------- 14 0,-1 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAau--------- 2 0,-1 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAc---------- 75 0,-1 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAU---------- 7490 0,0 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAUa--------- 106 0,0 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAUc--------- 2 0,0 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAUU--------- 1063 0,1 -------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAUUu-------- 17 0,1 --------------------------------------------------------AAUGCCCCUAAAAAUCCUU------------ 16 1,-2 --------------------------------------------------------AAUGCCCCUAAAAAUCCUUuu---------- 2 1,-2 --------------------------------------------------------AAUGCCCCUAAAAAUCCUUA----------- 44 1,-1 --------------------------------------------------------AAUGCCCCUAAAAAUCCUUAU---------- 278 1,0 --------------------------------------------------------AAUGCCCCUAAAAAUCCUUAUa--------- 2 1,0 --------------------------------------------------------AAUGCCCCUAAAAAUCCUUAUU--------- 41 1,1 ---------------------------------------------------------AUGCCCCUAAAAAUCCUUA----------- 2 2,-1 ---------------------------------------------------------AUGCCCCUAAAAAUCCUUAa---------- 2 2,-1 ---------------------------------------------------------AUGCCCCUAAAAAUCCUUAU---------- 5 2,0 >hsa-mir-365-2 mi:29-50;MA:68-89 Tumor agaguguucaaggacagcaagaaaaaugAGGGACUUUCAGGGGCAGCUGUguuuucugacucagucaUAAUGCCCCUAAAAAUCCUUAUuguucuugcagugugcaucggg ---------------------------GAGGGACUUUCAGGGGCAGC---------------------------------------------------------------- 2 -1,-3 ---------------------------GAGGGACUUUCAGGGGCAGCU--------------------------------------------------------------- 2 -1,-2 ---------------------------GAGGGACUUUCAGGGGCAGCUuu------------------------------------------------------------- 4 -1,-2 ---------------------------GAGGGACUUUCAGGGGCAGCUGU------------------------------------------------------------- 16 -1,0 ----------------------------AGGGACUUUCAGGGGCAGCUGUG------------------------------------------------------------ 40 0,1 ----------------------------AGGGACUUUCAGGGGCAGCUGUGU----------------------------------------------------------- 2 0,2 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCC-------------------------- 2 0,-4 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCU------------------------- 90 0,-3 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUa------------------------ 4 0,-3 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUU------------------------ 1090 0,-2 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUc----------------------- 2 0,-2 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUu----------------------- 153 0,-2 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUuu---------------------- 214 0,-2 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUA----------------------- 1486 0,-1 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAa---------------------- 165 0,-1 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAaa--------------------- 14 0,-1 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAau--------------------- 2 0,-1 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAc---------------------- 75 0,-1 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAU---------------------- 7490 0,0 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAUa--------------------- 106 0,0 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAUc--------------------- 2 0,0 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAUU--------------------- 1063 0,1 -------------------------------------------------------------------UAAUGCCCCUAAAAAUCCUUAUUu-------------------- 17 0,1 --------------------------------------------------------------------AAUGCCCCUAAAAAUCCUU------------------------ 16 1,-2 --------------------------------------------------------------------AAUGCCCCUAAAAAUCCUUuu---------------------- 2 1,-2 --------------------------------------------------------------------AAUGCCCCUAAAAAUCCUUA----------------------- 44 1,-1 --------------------------------------------------------------------AAUGCCCCUAAAAAUCCUUAU---------------------- 278 1,0 --------------------------------------------------------------------AAUGCCCCUAAAAAUCCUUAUa--------------------- 2 1,0 --------------------------------------------------------------------AAUGCCCCUAAAAAUCCUUAUU--------------------- 41 1,1 ---------------------------------------------------------------------AUGCCCCUAAAAAUCCUUA----------------------- 2 2,-1 ---------------------------------------------------------------------AUGCCCCUAAAAAUCCUUAa---------------------- 2 2,-1 ---------------------------------------------------------------------AUGCCCCUAAAAAUCCUUAU---------------------- 5 2,0 >hsa-mir-3652 5pM:1-18 Tumor CGGCUGGAGGUGUGAGGAuccgaacccaggggugggggguggaggcggcuccugcgaucgaaggggacuugagacucaccggccgcacgccaugagggcccugugggugcugggccucugcugcguccugc -----------------------------------------------------------------------AGACUCACCGGCCGCACGCC---------------------------------------- 2 >hsa-mir-3653 3pM:75-92 Tumor ucccuggggaccccuggcagccccuccugaugauucuucuuccugagcacgcucaugaugagcaaacugagccuCUAAGAAGUUGACUGAAGgggcugcuuccccaagga ----------------------CCUCCUGAUGAUUCUUCUU--------------------------------------------------------------------- 2 -----------------------CUCCUGAUGAUUCUUCUUCCUGAGC-------------------------------------------------------------- 6 --------------------------------------CUUCCUGAGCACGCUCAUGAUGAG------------------------------------------------ 11 ---------------------------------------UUCCUGAGCACGCUCAUGAUGAG------------------------------------------------ 2 -------------------------------------------------CGCUCAUGAUGAGCAAACUGAGC-------------------------------------- 19 --------------------------------------------------GCUCAUGAUGAGCAAACUGAGC-------------------------------------- 4 ------------------------------------------------------------------------CUCUAAGAAGUUGACUGAAG------------------ 56 -2,0 -------------------------------------------------------------------------UCUAAGAAGUUGACUGAAG------------------ 12 -1,0 --------------------------------------------------------------------------CUAAGAAGUUGACUGAAG------------------ 40 0,0 >hsa-mir-3656 3pM:49-65 Tumor cuuucggccagcgggacggcauccgaggugggcuaggcucgggcccguGGCGGGUGCGGGGGUGGgagg ------------------------------------------------GGCGGGUGCGGGGGUGGG--- 13 0,1 >hsa-mir-3657 3pM:69-89 Tumor ugugucccauaauuaaauaaugaaaucugaaaucaccaauaaugggacacuaaugugauuaauguuguUGUGUCCCAUUAUUGGUGAUUucagauuucauauaugauuaaggacaua -------------------------------------------------------------------UUGUGUCCCAUUAUUGGUGAUU---------------------------- 4 -1,0 --------------------------------------------------------------------UGUGUCCCAUUAUUGGUGA------------------------------ 2 0,-2 --------------------------------------------------------------------UGUGUCCCAUUAUUGGUGAUU---------------------------- 2 0,0 >hsa-mir-3659 3pM:59-79 Tumor ucuacaagcagauacaaggaugcccuuguacacaacacacgugcugcuuguauagacaUGAGUGUUGUCUACGAGGGCAuccuugugucugugugugug ----------------------------------------------------------UGAGUGUUGUCUACGAGGGCAU------------------- 2 0,1 >hsa-mir-3662 3pM:55-78 Tumor uguguuuuccucaacgcucacaguuacacuucuuacucucaauccauucauauuGAAAAUGAUGAGUAGUGACUGAUGaagcacaaaucagccaa ------------------------------------------------------GAAAAUGAUGAGUAGUGACUGAUG----------------- 2 0,0 >hsa-mir-3664 5p:21-42;3p:59-80 Tumor cuguaaacuugaagguagggAACUCUGUCUUCACUCAUGAGUaccuuccaacacgagcUCUCAGGAGUAAAGACAGAGUUcccuaccuucaauguggau --------------------AACUCUGUCUUCACUCAUGAG---------------------------------------------------------- 4 0,-1 --------------------AACUCUGUCUUCACUCAUGAGU--------------------------------------------------------- 19 0,0 ---------------------ACUCUGUCUUCACUCAUGAGU--------------------------------------------------------- 2 1,0 ----------------------------------------------------------UCUCAGGAGUAAAGACAGAGU-------------------- 2 0,-1 ----------------------------------------------------------UCUCAGGAGUAAAGACAGAGUU------------------- 2 0,0 ----------------------------------------------------------UCUCAGGAGUAAAGACAGAGUUC------------------ 2 0,1 ------------------------------------------------------------UCAGGAGUAAAGACAGAGUUC------------------ 2 2,1 >hsa-mir-3667 5p:9-30;3p:45-66 Tumor ugaggaugAAAGACCCAUUGAGGAGAAGGUucugcuggcugagaACCUUCCUCUCCAUGGGUCUUUcauccuca --------------------------------------------ACCUUCCUCUCCAUGGGU------------ 2 0,-4 >hsa-mir-3676 3pM:60-79 Tumor uugguuaaagcgccugucuaguaaacaggagauccuggguucgaaucccagcggugccuCCGUGUUUCCCCCACGCUUUugccaa -------------------AGUAAACAGGAGAUCCUGGGU--------------------------------------------- 2 --------------------GUAAACAGGAGAUCCUGGGU--------------------------------------------- 55 --------------------GUAAACAGGAGAUCCUGGGUUC------------------------------------------- 2 ---------------------UAAACAGGAGAUCCUGGGU--------------------------------------------- 4 ---------------------UAAACAGGAGAUCCUGGGUU-------------------------------------------- 2 ---------------------UAAACAGGAGAUCCUGGGUUC------------------------------------------- 20 ---------------------UAAACAGGAGAUCCUGGGUUCG------------------------------------------ 162 ---------------------UAAACAGGAGAUCCUGGGUUCGu----------------------------------------- 4 ---------------------UAAACAGGAGAUCCUGGGUUCGA----------------------------------------- 42 ----------------------AAACAGGAGAUCCUGGGUU-------------------------------------------- 4 ----------------------AAACAGGAGAUCCUGGGUUC------------------------------------------- 16 ----------------------AAACAGGAGAUCCUGGGUUCG------------------------------------------ 152 ----------------------AAACAGGAGAUCCUGGGUUCGu----------------------------------------- 2 ----------------------AAACAGGAGAUCCUGGGUUCGA----------------------------------------- 9 -----------------------AACAGGAGAUCCUGGGUUCG------------------------------------------ 14 ------------------------ACAGGAGAUCCUGGGUUC------------------------------------------- 12 ------------------------ACAGGAGAUCCUGGGUUCG------------------------------------------ 21 -------------------------CAGGAGAUCCUGGGUUCG------------------------------------------ 2 -------------------------CAGGAGAUCCUGGGUUCGAA---------------------------------------- 4 --------------------------AGGAGAUCCUGGGUUCGAAUCCCA----------------------------------- 2 -----------------------------------------------------------CCGUGUUUCCCCCACGCUUU------ 2 0,0 >hsa-mir-3677 5p:3-24;3p:39-60 Tumor ggCAGUGGCCAGAGCCCUGCAGUGcugggcaugggcuuCUCGUGGGCUCUGGCCACGGCC --CAGUGGCCAGAGCCCUGCAGUGu----------------------------------- 2 0,0 --------------------------------------CUCGUGGGCUCUGGCCACGGC- 4 0,-1 --------------------------------------CUCGUGGGCUCUGGCCACGGCC 11 0,0 >hsa-mir-3679 5p:6-28;3p:44-65 Tumor cguggUGAGGAUAUGGCAGGGAAGGGGAguuucccucuauuccCUUCCCCCCAGUAAUCUUCAUCaug -----UGAGGAUAUGGCAGGGAAG-------------------------------------------- 2 0,-4 >hsa-mir-3687 3pM:35-58 Tumor cgcgcgugcgcccgagcgcggcccgguggucccuCCCGGACAGGCGUUCGUGCGACGUgug ------------------------------------CGGACAGGCGUUCGUGCG------- 31 2,-4 ------------------------------------CGGACAGGCGUUCGUGCGA------ 2 2,-3 ------------------------------------CGGACAGGCGUUCGUGCGAC----- 14 2,-2 ------------------------------------CGGACAGGCGUUCGUGCGACG---- 37 2,-1 >hsa-mir-369 5p:9-30;3p:44-64 Tumor uugaagggAGAUCGACCGUGUUAUAUUCGCuuuauugacuucgAAUAAUACAUGGUUGAUCUUUucucag --------AGAUCGACCGUGUUAUAUU------------------------------------------- 2 0,-3 --------AGAUCGACCGUGUUAUAUUC------------------------------------------ 17 0,-2 --------AGAUCGACCGUGUUAUAUUCG----------------------------------------- 389 0,-1 --------AGAUCGACCGUGUUAUAUUCGC---------------------------------------- 16 0,0 --------AGAUCGACCGUGUUAUAUUCGCU--------------------------------------- 13 0,1 ---------GAUCGACCGUGUUAUAUUCG----------------------------------------- 4 1,-1 ------------------------------------------GAAUAAUACAUGGUUGAUCUU------- 6 -1,-1 ------------------------------------------GAAUAAUACAUGGUUGAUCUUU------ 52 -1,0 -------------------------------------------AAUAAUACAUGGUUGAUCUU------- 100 0,-1 -------------------------------------------AAUAAUACAUGGUUGAUCUUa------ 2 0,-1 -------------------------------------------AAUAAUACAUGGUUGAUCUUc------ 4 0,-1 -------------------------------------------AAUAAUACAUGGUUGAUCUUU------ 2226 0,0 -------------------------------------------AAUAAUACAUGGUUGAUCUUUa----- 4 0,0 -------------------------------------------AAUAAUACAUGGUUGAUCUUUaa---- 2 0,0 -------------------------------------------AAUAAUACAUGGUUGAUCUUUU----- 100 0,1 -------------------------------------------AAUAAUACAUGGUUGAUCUUUUu---- 2 0,1 --------------------------------------------AUAAUACAUGGUUGAUCUUU------ 4 1,0 >hsa-mir-3690 5pM:10-32 Tumor cccaucuccACCUGGACCCAGCGUAGACAAAGagguguuucuacuccauaucuaccuggacccaguguagauggg ---------ACCUGGACCCAGCGUAGACA---------------------------------------------- 2 0,-3 ---------ACCUGGACCCAGCGUAGACAA--------------------------------------------- 2 0,-2 ---------ACCUGGACCCAGCGUAGACAAAG------------------------------------------- 4 0,0 >hsa-mir-370 3pM:48-69 Tumor agacagagaagccaggucacgucucugcaguuacacagcucacgaguGCCUGCUGGGGUGGAACCUGGUcugucu -----------------------------------------------GCCUGCUGGGGUGGAACCUGa------- 2 0,-2 -----------------------------------------------GCCUGCUGGGGUGGAACCUGG------- 18 0,-1 -----------------------------------------------GCCUGCUGGGGUGGAACCUGGa------ 5 0,-1 -----------------------------------------------GCCUGCUGGGGUGGAACCUGGU------ 390 0,0 -----------------------------------------------GCCUGCUGGGGUGGAACCUGGUa----- 47 0,0 -----------------------------------------------GCCUGCUGGGGUGGAACCUGGUaa---- 2 0,0 -----------------------------------------------GCCUGCUGGGGUGGAACCUGGUau---- 4 0,0 -----------------------------------------------GCCUGCUGGGGUGGAACCUGGUu----- 30 0,0 >hsa-mir-373 mi:6-27;MA:44-66 Tumor gggauACUCAAAAUGGGGGCGCUUUCCuuuuugucuguacuggGAAGUGCUUCGAUUUUGGGGUGUccc -------------------------------------------GAAGUGCUUCGAUUUUGGGGUGU--- 2 0,0 >hsa-mir-374a MA:12-33;mi:42-63 Tumor uacaucggccaUUAUAAUACAACCUGAUAAGUGuuauagcaCUUAUCAGAUUGUAUUGUAAUUgucugugua -----------UUAUAAUACAACCUGAUA------------------------------------------- 127 0,-4 -----------UUAUAAUACAACCUGAUAA------------------------------------------ 167 0,-3 -----------UUAUAAUACAACCUGAUAAa----------------------------------------- 33 0,-3 -----------UUAUAAUACAACCUGAUAAaa---------------------------------------- 4 0,-3 -----------UUAUAAUACAACCUGAUAAau---------------------------------------- 11 0,-3 -----------UUAUAAUACAACCUGAUAAu----------------------------------------- 2 0,-3 -----------UUAUAAUACAACCUGAUAAuu---------------------------------------- 29 0,-3 -----------UUAUAAUACAACCUGAUAAG----------------------------------------- 1041 0,-2 -----------UUAUAAUACAACCUGAUAAGa---------------------------------------- 105 0,-2 -----------UUAUAAUACAACCUGAUAAGaa--------------------------------------- 2 0,-2 -----------UUAUAAUACAACCUGAUAAGc---------------------------------------- 18 0,-2 -----------UUAUAAUACAACCUGAUAAGg---------------------------------------- 25 0,-2 -----------UUAUAAUACAACCUGAUAAGU---------------------------------------- 15389 0,-1 -----------UUAUAAUACAACCUGAUAAGUa--------------------------------------- 397 0,-1 -----------UUAUAAUACAACCUGAUAAGUaa-------------------------------------- 37 0,-1 -----------UUAUAAUACAACCUGAUAAGUc--------------------------------------- 4 0,-1 -----------UUAUAAUACAACCUGAUAAGUu--------------------------------------- 59 0,-1 -----------UUAUAAUACAACCUGAUAAGUG--------------------------------------- 21052 0,0 -----------UUAUAAUACAACCUGAUAAGUGa-------------------------------------- 3083 0,0 -----------UUAUAAUACAACCUGAUAAGUGaa------------------------------------- 20 0,0 -----------UUAUAAUACAACCUGAUAAGUGc-------------------------------------- 6 0,0 -----------UUAUAAUACAACCUGAUAAGUGg-------------------------------------- 14 0,0 -----------UUAUAAUACAACCUGAUAAGUGU-------------------------------------- 1388 0,1 -----------UUAUAAUACAACCUGAUAAGUGUU------------------------------------- 9 0,2 ------------UAUAAUACAACCUGAUAAG----------------------------------------- 2 1,-2 ------------UAUAAUACAACCUGAUAAGU---------------------------------------- 265 1,-1 ------------UAUAAUACAACCUGAUAAGUG--------------------------------------- 345 1,0 ------------UAUAAUACAACCUGAUAAGUGa-------------------------------------- 50 1,0 ------------UAUAAUACAACCUGAUAAGUGU-------------------------------------- 27 1,1 -------------AUAAUACAACCUGAUAAGU---------------------------------------- 27 2,-1 -------------AUAAUACAACCUGAUAAGUG--------------------------------------- 40 2,0 -------------AUAAUACAACCUGAUAAGUGa-------------------------------------- 7 2,0 -------------AUAAUACAACCUGAUAAGUGU-------------------------------------- 6 2,1 ----------------------------------------ACUUAUCAGAUUGUAUUGU------------- 2 -1,-4 ----------------------------------------ACUUAUCAGAUUGUAUUGUA------------ 2 -1,-3 ----------------------------------------ACUUAUCAGAUUGUAUUGUAAU---------- 7 -1,-1 -----------------------------------------CUUAUCAGAUUGUAUUGU------------- 6 0,-4 -----------------------------------------CUUAUCAGAUUGUAUUGUA------------ 37 0,-3 -----------------------------------------CUUAUCAGAUUGUAUUGUAuu---------- 2 0,-3 -----------------------------------------CUUAUCAGAUUGUAUUGUAA----------- 251 0,-2 -----------------------------------------CUUAUCAGAUUGUAUUGUAAa---------- 40 0,-2 -----------------------------------------CUUAUCAGAUUGUAUUGUAAaa--------- 13 0,-2 -----------------------------------------CUUAUCAGAUUGUAUUGUAAU---------- 955 0,-1 -----------------------------------------CUUAUCAGAUUGUAUUGUAAUa--------- 8 0,-1 -----------------------------------------CUUAUCAGAUUGUAUUGUAAUU--------- 2965 0,0 -----------------------------------------CUUAUCAGAUUGUAUUGUAAUUa-------- 115 0,0 -----------------------------------------CUUAUCAGAUUGUAUUGUAAUUu-------- 28 0,0 ------------------------------------------UUAUCAGAUUGUAUUGUAA----------- 5 1,-2 ------------------------------------------UUAUCAGAUUGUAUUGUAAU---------- 6 1,-1 ------------------------------------------UUAUCAGAUUGUAUUGUAAUU--------- 61 1,0 >hsa-mir-374b MA:11-32;mi:41-62 Tumor acucggauggAUAUAAUACAACCUGCUAAGUGuccuagcaCUUAGCAGGUUGUAUUAUCAUUguccgugucu ----------AUAUAAUACAACCUGCUA-------------------------------------------- 177 0,-4 ----------AUAUAAUACAACCUGCUAu------------------------------------------- 4 0,-4 ----------AUAUAAUACAACCUGCUAA------------------------------------------- 120 0,-3 ----------AUAUAAUACAACCUGCUAAa------------------------------------------ 4 0,-3 ----------AUAUAAUACAACCUGCUAAau----------------------------------------- 19 0,-3 ----------AUAUAAUACAACCUGCUAAu------------------------------------------ 2 0,-3 ----------AUAUAAUACAACCUGCUAAuu----------------------------------------- 29 0,-3 ----------AUAUAAUACAACCUGCUAAG------------------------------------------ 1151 0,-2 ----------AUAUAAUACAACCUGCUAAGa----------------------------------------- 73 0,-2 ----------AUAUAAUACAACCUGCUAAGc----------------------------------------- 14 0,-2 ----------AUAUAAUACAACCUGCUAAGg----------------------------------------- 34 0,-2 ----------AUAUAAUACAACCUGCUAAGU----------------------------------------- 14663 0,-1 ----------AUAUAAUACAACCUGCUAAGUa---------------------------------------- 244 0,-1 ----------AUAUAAUACAACCUGCUAAGUaa--------------------------------------- 17 0,-1 ----------AUAUAAUACAACCUGCUAAGUau--------------------------------------- 4 0,-1 ----------AUAUAAUACAACCUGCUAAGUc---------------------------------------- 2 0,-1 ----------AUAUAAUACAACCUGCUAAGUu---------------------------------------- 66 0,-1 ----------AUAUAAUACAACCUGCUAAGUG---------------------------------------- 13333 0,0 ----------AUAUAAUACAACCUGCUAAGUGa--------------------------------------- 3265 0,0 ----------AUAUAAUACAACCUGCUAAGUGaa-------------------------------------- 24 0,0 ----------AUAUAAUACAACCUGCUAAGUGc--------------------------------------- 9 0,0 ----------AUAUAAUACAACCUGCUAAGUGg--------------------------------------- 17 0,0 ----------AUAUAAUACAACCUGCUAAGUGU--------------------------------------- 2584 0,1 ----------AUAUAAUACAACCUGCUAAGUGUa-------------------------------------- 2 0,1 ----------AUAUAAUACAACCUGCUAAGUGUu-------------------------------------- 6 0,1 -----------UAUAAUACAACCUGCUAAGU----------------------------------------- 33 1,-1 -----------UAUAAUACAACCUGCUAAGUG---------------------------------------- 16 1,0 -----------UAUAAUACAACCUGCUAAGUGa--------------------------------------- 4 1,0 -----------UAUAAUACAACCUGCUAAGUGU--------------------------------------- 2 1,1 ------------AUAAUACAACCUGCUAAGU----------------------------------------- 6 2,-1 ------------AUAAUACAACCUGCUAAGUG---------------------------------------- 4 2,0 ------------AUAAUACAACCUGCUAAGUGU--------------------------------------- 2 2,1 --------------------------------------CACUUAGCAGGUUGUAUUAUCA------------ 2 -2,-2 ---------------------------------------ACUUAGCAGGUUGUAUUAUC------------- 5 -1,-3 ---------------------------------------ACUUAGCAGGUUGUAUUAUCA------------ 2 -1,-2 ---------------------------------------ACUUAGCAGGUUGUAUUAUCAU----------- 17 -1,-1 ----------------------------------------CUUAGCAGGUUGUAUUAUC------------- 8 0,-3 ----------------------------------------CUUAGCAGGUUGUAUUAUCA------------ 15 0,-2 ----------------------------------------CUUAGCAGGUUGUAUUAUCAU----------- 32 0,-1 ----------------------------------------CUUAGCAGGUUGUAUUAUCAUU---------- 261 0,0 ----------------------------------------CUUAGCAGGUUGUAUUAUCAUUu--------- 2 0,0 -----------------------------------------UUAGCAGGUUGUAUUAUCAUU---------- 2 1,0 >hsa-mir-374c 5pM:13-34 Tumor acacggacaaugAUAAUACAACCUGCUAAGUGCUaggacacuuagcagguuguauuauauccauccgagu ------------AUAAUACAACCUGCUAAGU--------------------------------------- 6 0,-3 ------------AUAAUACAACCUGCUAAGUG-------------------------------------- 4 0,-2 >hsa-mir-375 3pM:40-61 Tumor ccccgcgacgagccccucgcacaaaccggaccugagcguUUUGUUCGUUCGGCUCGCGUGAggc --------------------------------------UUUUGUUCGUUCGGCUCGC------- 6 -1,-4 --------------------------------------UUUUGUUCGUUCGGCUCGCG------ 65 -1,-3 --------------------------------------UUUUGUUCGUUCGGCUCGCGa----- 4 -1,-3 --------------------------------------UUUUGUUCGUUCGGCUCGCGU----- 169 -1,-2 --------------------------------------UUUUGUUCGUUCGGCUCGCGUaa--- 2 -1,-2 --------------------------------------UUUUGUUCGUUCGGCUCGCGUu---- 7 -1,-2 --------------------------------------UUUUGUUCGUUCGGCUCGCGUG---- 234 -1,-1 --------------------------------------UUUUGUUCGUUCGGCUCGCGUGc--- 11 -1,-1 --------------------------------------UUUUGUUCGUUCGGCUCGCGUGu--- 173 -1,-1 --------------------------------------UUUUGUUCGUUCGGCUCGCGUGA--- 909 -1,0 --------------------------------------UUUUGUUCGUUCGGCUCGCGUGAa-- 23 -1,0 --------------------------------------UUUUGUUCGUUCGGCUCGCGUGAu-- 22 -1,0 ---------------------------------------UUUGUUCGUUCGGCUCGC------- 292 0,-4 ---------------------------------------UUUGUUCGUUCGGCUCGCa------ 2 0,-4 ---------------------------------------UUUGUUCGUUCGGCUCGCaa----- 6 0,-4 ---------------------------------------UUUGUUCGUUCGGCUCGCG------ 2041 0,-3 ---------------------------------------UUUGUUCGUUCGGCUCGCGa----- 136 0,-3 ---------------------------------------UUUGUUCGUUCGGCUCGCGaa---- 2 0,-3 ---------------------------------------UUUGUUCGUUCGGCUCGCGau---- 6 0,-3 ---------------------------------------UUUGUUCGUUCGGCUCGCGc----- 9 0,-3 ---------------------------------------UUUGUUCGUUCGGCUCGCGg----- 23 0,-3 ---------------------------------------UUUGUUCGUUCGGCUCGCGU----- 2802 0,-2 ---------------------------------------UUUGUUCGUUCGGCUCGCGUa---- 51 0,-2 ---------------------------------------UUUGUUCGUUCGGCUCGCGUaa--- 187 0,-2 ---------------------------------------UUUGUUCGUUCGGCUCGCGUau--- 16 0,-2 ---------------------------------------UUUGUUCGUUCGGCUCGCGUu---- 234 0,-2 ---------------------------------------UUUGUUCGUUCGGCUCGCGUuu--- 76 0,-2 ---------------------------------------UUUGUUCGUUCGGCUCGCGUG---- 5035 0,-1 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGc--- 1534 0,-1 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGg--- 202 0,-1 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGu--- 3116 0,-1 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGuu-- 66 0,-1 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGA--- 62632 0,0 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGAa-- 3053 0,0 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGAaa- 448 0,0 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGAau- 359 0,0 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGAc-- 44 0,0 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGAu-- 2876 0,0 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGAuu- 220 0,0 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGAG-- 79 0,1 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGAGa- 27 0,1 ---------------------------------------UUUGUUCGUUCGGCUCGCGUGAGu- 15 0,1 ----------------------------------------UUGUUCGUUCGGCUCGCG------ 42 1,-3 ----------------------------------------UUGUUCGUUCGGCUCGCGa----- 2 1,-3 ----------------------------------------UUGUUCGUUCGGCUCGCGU----- 41 1,-2 ----------------------------------------UUGUUCGUUCGGCUCGCGUaa--- 3 1,-2 ----------------------------------------UUGUUCGUUCGGCUCGCGUau--- 2 1,-2 ----------------------------------------UUGUUCGUUCGGCUCGCGUuu--- 2 1,-2 ----------------------------------------UUGUUCGUUCGGCUCGCGUG---- 151 1,-1 ----------------------------------------UUGUUCGUUCGGCUCGCGUGc--- 36 1,-1 ----------------------------------------UUGUUCGUUCGGCUCGCGUGu--- 84 1,-1 ----------------------------------------UUGUUCGUUCGGCUCGCGUGA--- 2618 1,0 ----------------------------------------UUGUUCGUUCGGCUCGCGUGAa-- 136 1,0 ----------------------------------------UUGUUCGUUCGGCUCGCGUGAaa- 33 1,0 ----------------------------------------UUGUUCGUUCGGCUCGCGUGAau- 19 1,0 ----------------------------------------UUGUUCGUUCGGCUCGCGUGAc-- 7 1,0 ----------------------------------------UUGUUCGUUCGGCUCGCGUGAu-- 219 1,0 ----------------------------------------UUGUUCGUUCGGCUCGCGUGAuu- 17 1,0 ----------------------------------------UUGUUCGUUCGGCUCGCGUGAG-- 2 1,1 -----------------------------------------UGUUCGUUCGGCUCGCGUG---- 7 2,-1 -----------------------------------------UGUUCGUUCGGCUCGCGUGc--- 5 2,-1 -----------------------------------------UGUUCGUUCGGCUCGCGUGA--- 195 2,0 -----------------------------------------UGUUCGUUCGGCUCGCGUGAa-- 16 2,0 -----------------------------------------UGUUCGUUCGGCUCGCGUGAaa- 3 2,0 -----------------------------------------UGUUCGUUCGGCUCGCGUGAau- 9 2,0 -----------------------------------------UGUUCGUUCGGCUCGCGUGAu-- 52 2,0 -----------------------------------------UGUUCGUUCGGCUCGCGUGAuu- 24 2,0 >hsa-mir-376a-1 mi:7-28;MA:44-64 Tumor uaaaagGUAGAUUCUCCUUCUAUGAGUAcauuauuuaugauuaAUCAUAGAGGAAAAUCCACGUuuuc ----AGGUAGAUUCUCCUUCUAUGAG------------------------------------------ 2 -2,-2 ------GUAGAUUCUCCUUCUAUGAG------------------------------------------ 8 0,-2 ------GUAGAUUCUCCUUCUAUGAGa----------------------------------------- 2 0,-2 ------GUAGAUUCUCCUUCUAUGAGU----------------------------------------- 160 0,-1 ------GUAGAUUCUCCUUCUAUGAGUA---------------------------------------- 25 0,0 ------GUAGAUUCUCCUUCUAUGAGUAa--------------------------------------- 11 0,0 ------GUAGAUUCUCCUUCUAUGAGUAC--------------------------------------- 77 0,1 -------UAGAUUCUCCUUCUAUGAGUAa--------------------------------------- 2 1,0 -------UAGAUUCUCCUUCUAUGAGUAC--------------------------------------- 14 1,1 ------------------------------------------AAUCAUAGAGGAAAAUCCACG----- 2 -1,-1 ------------------------------------------AAUCAUAGAGGAAAAUCCACGU---- 29 -1,0 ------------------------------------------AAUCAUAGAGGAAAAUCCACGUU--- 2 -1,1 -------------------------------------------AUCAUAGAGGAAAAUCCACG----- 2 0,-1 -------------------------------------------AUCAUAGAGGAAAAUCCACGU---- 203 0,0 -------------------------------------------AUCAUAGAGGAAAAUCCACGUU--- 4 0,1 >hsa-mir-376a-2 3pM:50-70 Tumor gguauuuaaaagguagauuuuccuucuaugguuacguguuugaugguuaAUCAUAGAGGAAAAUCCACGUuuucaguauc -----------GGUAGAUUUUCCUUCUAUGGUU----------------------------------------------- 2 ------------GUAGAUUUUCCUUCUAUGGUU----------------------------------------------- 34 ------------GUAGAUUUUCCUUCUAUGGUUu---------------------------------------------- 2 ------------GUAGAUUUUCCUUCUAUGGUUA---------------------------------------------- 38 ------------------------------------------------AAUCAUAGAGGAAAAUCCACG----------- 2 -1,-1 ------------------------------------------------AAUCAUAGAGGAAAAUCCACGU---------- 29 -1,0 ------------------------------------------------AAUCAUAGAGGAAAAUCCACGUU--------- 2 -1,1 -------------------------------------------------AUCAUAGAGGAAAAUCCACG----------- 2 0,-1 -------------------------------------------------AUCAUAGAGGAAAAUCCACGU---------- 203 0,0 -------------------------------------------------AUCAUAGAGGAAAAUCCACGUU--------- 4 0,1 >hsa-mir-376b 3pM:62-83 Tumor caguccuucuuugguauuuaaaacguggauauuccuucuauguuuacgugauuccugguuaAUCAUAGAGGAAAAUCCAUGUUuucaguaucaaaugcug ------------------------GUGGAUAUUCCUUCUAUGUU-------------------------------------------------------- 8 ------------------------GUGGAUAUUCCUUCUAUGUUU------------------------------------------------------- 87 ------------------------GUGGAUAUUCCUUCUAUGUUUA------------------------------------------------------ 17 -------------------------UGGAUAUUCCUUCUAUGUUU------------------------------------------------------- 22 -------------------------UGGAUAUUCCUUCUAUGUUUA------------------------------------------------------ 5 -------------------------------------------------------------AUCAUAGAGGAAAAUCCAUG------------------- 2 0,-2 -------------------------------------------------------------AUCAUAGAGGAAAAUCCAUGU------------------ 608 0,-1 -------------------------------------------------------------AUCAUAGAGGAAAAUCCAUGUa----------------- 6 0,-1 -------------------------------------------------------------AUCAUAGAGGAAAAUCCAUGUU----------------- 335 0,0 -------------------------------------------------------------AUCAUAGAGGAAAAUCCAUGUUa---------------- 9 0,0 -------------------------------------------------------------AUCAUAGAGGAAAAUCCAUGUUU---------------- 68 0,1 --------------------------------------------------------------UCAUAGAGGAAAAUCCAUGUUU---------------- 9 1,1 >hsa-mir-376c 3pM:43-63 Tumor aaaagguggauauuccuucuauguuuauguuauuuaugguuaAACAUAGAGGAAAUUCCACGUuuu -----GUGGAUAUUCCUUCUAUGUU----------------------------------------- 8 -----GUGGAUAUUCCUUCUAUGUUU---------------------------------------- 87 -----GUGGAUAUUCCUUCUAUGUUUA--------------------------------------- 17 ------UGGAUAUUCCUUCUAUGUUU---------------------------------------- 22 ------UGGAUAUUCCUUCUAUGUUUA--------------------------------------- 5 -----------------------------------------AAACAUAGAGGAAAUUCCACG---- 2 -1,-1 ------------------------------------------AACAUAGAGGAAAUUCCA------ 4 0,-3 ------------------------------------------AACAUAGAGGAAAUUCCACau--- 4 0,-2 ------------------------------------------AACAUAGAGGAAAUUCCACG---- 203 0,-1 ------------------------------------------AACAUAGAGGAAAUUCCACGa--- 6 0,-1 ------------------------------------------AACAUAGAGGAAAUUCCACGc--- 24 0,-1 ------------------------------------------AACAUAGAGGAAAUUCCACGU--- 4174 0,0 ------------------------------------------AACAUAGAGGAAAUUCCACGUa-- 67 0,0 ------------------------------------------AACAUAGAGGAAAUUCCACGUaa- 7 0,0 ------------------------------------------AACAUAGAGGAAAUUCCACGUau- 4 0,0 ------------------------------------------AACAUAGAGGAAAUUCCACGUU-- 335 0,1 ------------------------------------------AACAUAGAGGAAAUUCCACGUUa- 9 0,1 ------------------------------------------AACAUAGAGGAAAUUCCACGUUU- 36 0,2 -------------------------------------------ACAUAGAGGAAAUUCCACGU--- 53 1,0 -------------------------------------------ACAUAGAGGAAAUUCCACGUU-- 6 1,1 -------------------------------------------ACAUAGAGGAAAUUCCACGUUU- 16 1,2 --------------------------------------------CAUAGAGGAAAUUCCACGU--- 4 2,0 --------------------------------------------CAUAGAGGAAAUUCCACGUUU- 2 2,2 >hsa-mir-377 mi:7-28;MA:45-66 Tumor uugagcAGAGGUUGCCCUUGGUGAAUUCgcuuuauuuauguugaAUCACACAAAGGCAACUUUUGUuug ------AGAGGUUGCCCUUGGUGAAU------------------------------------------- 18 0,-2 ------AGAGGUUGCCCUUGGUGAAUU------------------------------------------ 15 0,-1 ------AGAGGUUGCCCUUGGUGAAUUC----------------------------------------- 86 0,0 ------AGAGGUUGCCCUUGGUGAAUUCu---------------------------------------- 2 0,0 ------AGAGGUUGCCCUUGGUGAAUUCG---------------------------------------- 2 0,1 -------------------------------------------AAUCACACAAAGGCAACUUUUG---- 48 -1,-1 -------------------------------------------AAUCACACAAAGGCAACUUUUGa--- 3 -1,-1 -------------------------------------------AAUCACACAAAGGCAACUUUUGU--- 184 -1,0 --------------------------------------------AUCACACAAAGGCAACUU------- 2 0,-4 --------------------------------------------AUCACACAAAGGCAACUUUU----- 32 0,-2 --------------------------------------------AUCACACAAAGGCAACUUUUau--- 2 0,-2 --------------------------------------------AUCACACAAAGGCAACUUUUuu--- 7 0,-2 --------------------------------------------AUCACACAAAGGCAACUUUUG---- 449 0,-1 --------------------------------------------AUCACACAAAGGCAACUUUUGa--- 68 0,-1 --------------------------------------------AUCACACAAAGGCAACUUUUGc--- 2 0,-1 --------------------------------------------AUCACACAAAGGCAACUUUUGU--- 3430 0,0 --------------------------------------------AUCACACAAAGGCAACUUUUGUa-- 6 0,0 --------------------------------------------AUCACACAAAGGCAACUUUUGUU-- 18 0,1 --------------------------------------------AUCACACAAAGGCAACUUUUGUUU- 2 0,2 >hsa-mir-378 mi:5-26;MA:43-63 Tumor agggCUCCUGACUCCAGGUCCUGUGUguuaccuagaaauagcACUGGACUUGGAGUCAGAAGGccu ----CUCCUGACUCCAGGUCCUGU------------------------------------------ 12 0,-2 ----CUCCUGACUCCAGGUCCUGUG----------------------------------------- 58 0,-1 ----CUCCUGACUCCAGGUCCUGUGa---------------------------------------- 67 0,-1 ----CUCCUGACUCCAGGUCCUGUGU---------------------------------------- 648 0,0 ----CUCCUGACUCCAGGUCCUGUGUa--------------------------------------- 4 0,0 ----CUCCUGACUCCAGGUCCUGUGUaa-------------------------------------- 2 0,0 ----CUCCUGACUCCAGGUCCUGUGUu--------------------------------------- 4 0,0 -----UCCUGACUCCAGGUCCUGUGa---------------------------------------- 2 1,-1 -----UCCUGACUCCAGGUCCUGUGU---------------------------------------- 58 1,0 -----------------------------------------CACUGGACUUGGAGUCAGAAGG--- 13 -1,0 -----------------------------------------CACUGGACUUGGAGUCAGAAGGa-- 2 -1,0 -----------------------------------------CACUGGACUUGGAGUCAGAAGGC-- 10 -1,1 ------------------------------------------ACUGGACUUGGAGUCAGA------ 1043 0,-3 ------------------------------------------ACUGGACUUGGAGUCAGAu----- 4 0,-3 ------------------------------------------ACUGGACUUGGAGUCAGAA----- 384 0,-2 ------------------------------------------ACUGGACUUGGAGUCAGAAu---- 28 0,-2 ------------------------------------------ACUGGACUUGGAGUCAGAAG---- 6195 0,-1 ------------------------------------------ACUGGACUUGGAGUCAGAAGu--- 279 0,-1 ------------------------------------------ACUGGACUUGGAGUCAGAAGuu-- 6 0,-1 ------------------------------------------ACUGGACUUGGAGUCAGAAGG--- 10090 0,0 ------------------------------------------ACUGGACUUGGAGUCAGAAGGa-- 5030 0,0 ------------------------------------------ACUGGACUUGGAGUCAGAAGGaa- 1007 0,0 ------------------------------------------ACUGGACUUGGAGUCAGAAGGau- 74 0,0 ------------------------------------------ACUGGACUUGGAGUCAGAAGGg-- 6 0,0 ------------------------------------------ACUGGACUUGGAGUCAGAAGGu-- 1143 0,0 ------------------------------------------ACUGGACUUGGAGUCAGAAGGuu- 42 0,0 ------------------------------------------ACUGGACUUGGAGUCAGAAGGC-- 21949 0,1 ------------------------------------------ACUGGACUUGGAGUCAGAAGGCa- 4753 0,1 ------------------------------------------ACUGGACUUGGAGUCAGAAGGCaa 695 0,1 ------------------------------------------ACUGGACUUGGAGUCAGAAGGCau 921 0,1 ------------------------------------------ACUGGACUUGGAGUCAGAAGGCg- 96 0,1 ------------------------------------------ACUGGACUUGGAGUCAGAAGGCu- 1131 0,1 ------------------------------------------ACUGGACUUGGAGUCAGAAGGCuu 60 0,1 ------------------------------------------ACUGGACUUGGAGUCAGAAGGCC- 16 0,2 ------------------------------------------ACUGGACUUGGAGUCAGAAGGCCa 2 0,2 -------------------------------------------CUGGACUUGGAGUCAGAA----- 5 1,-2 -------------------------------------------CUGGACUUGGAGUCAGAAG---- 198 1,-1 -------------------------------------------CUGGACUUGGAGUCAGAAGG--- 557 1,0 -------------------------------------------CUGGACUUGGAGUCAGAAGGa-- 195 1,0 -------------------------------------------CUGGACUUGGAGUCAGAAGGaa- 50 1,0 -------------------------------------------CUGGACUUGGAGUCAGAAGGau- 4 1,0 -------------------------------------------CUGGACUUGGAGUCAGAAGGu-- 50 1,0 -------------------------------------------CUGGACUUGGAGUCAGAAGGuu- 2 1,0 -------------------------------------------CUGGACUUGGAGUCAGAAGGC-- 1922 1,1 -------------------------------------------CUGGACUUGGAGUCAGAAGGCa- 469 1,1 -------------------------------------------CUGGACUUGGAGUCAGAAGGCaa 158 1,1 -------------------------------------------CUGGACUUGGAGUCAGAAGGCau 108 1,1 -------------------------------------------CUGGACUUGGAGUCAGAAGGCg- 2 1,1 -------------------------------------------CUGGACUUGGAGUCAGAAGGCu- 334 1,1 -------------------------------------------CUGGACUUGGAGUCAGAAGGCuu 11 1,1 -------------------------------------------CUGGACUUGGAGUCAGAAGGCC- 14 1,2 --------------------------------------------UGGACUUGGAGUCAGAAG---- 6 2,-1 --------------------------------------------UGGACUUGGAGUCAGAAGG--- 9 2,0 --------------------------------------------UGGACUUGGAGUCAGAAGGa-- 4 2,0 --------------------------------------------UGGACUUGGAGUCAGAAGGC-- 55 2,1 --------------------------------------------UGGACUUGGAGUCAGAAGGCa- 8 2,1 --------------------------------------------UGGACUUGGAGUCAGAAGGCau 2 2,1 >hsa-mir-378b 3pM:34-52 Tumor ggucauugagucuucaaggcuaguggaaagagcACUGGACUUGGAGGCAGAAagacc ---------------------------------ACUGGACUUGGAGGCAGA------ 2 0,-1 ---------------------------------ACUGGACUUGGAGGCAGAA----- 49 0,0 ---------------------------------ACUGGACUUGGAGGCAGAAg---- 8 0,0 >hsa-mir-378c 5pM:11-35 Tumor ggaggccaucACUGGACUUGGAGUCAGAAGAGUGGagucgggucagacuucaacucugacuuugaagguggugagugccuc --------UCACUGGACUUGGAGUCAGAAG--------------------------------------------------- 2 -2,-5 ----------ACUGGACUUGGAGUCAGAAG--------------------------------------------------- 6195 0,-5 ----------ACUGGACUUGGAGUCAGAAGu-------------------------------------------------- 279 0,-5 ----------ACUGGACUUGGAGUCAGAAGuu------------------------------------------------- 6 0,-5 ----------ACUGGACUUGGAGUCAGAAGA-------------------------------------------------- 599 0,-4 ----------ACUGGACUUGGAGUCAGAAGAa------------------------------------------------- 112 0,-4 ----------ACUGGACUUGGAGUCAGAAGAaa------------------------------------------------ 54 0,-4 ----------ACUGGACUUGGAGUCAGAAGAc------------------------------------------------- 17 0,-4 ----------ACUGGACUUGGAGUCAGAAGAu------------------------------------------------- 2 0,-4 -----------CUGGACUUGGAGUCAGAAG--------------------------------------------------- 198 1,-5 -----------CUGGACUUGGAGUCAGAAGA-------------------------------------------------- 13 1,-4 ------------UGGACUUGGAGUCAGAAG--------------------------------------------------- 6 2,-5 >hsa-mir-378d-1 3pM:31-50 Tumor acuguuucuguccuuguucuuguuguuauuACUGGACUUGGAGUCAGAAAcagg ------------------------------ACUGGACUUGGAGUCAGA------ 1043 0,-2 ------------------------------ACUGGACUUGGAGUCAGAu----- 4 0,-2 ------------------------------ACUGGACUUGGAGUCAGAA----- 384 0,-1 ------------------------------ACUGGACUUGGAGUCAGAAu---- 28 0,-1 ------------------------------ACUGGACUUGGAGUCAGAAA---- 515 0,0 -------------------------------CUGGACUUGGAGUCAGAA----- 5 1,-1 -------------------------------CUGGACUUGGAGUCAGAAA---- 5 1,0 >hsa-mir-378d-2 5pM:22-41 Tumor gaaugguuacaaggagagaacACUGGACUUGGAGUCAGAAAacuuucauccaagucauucccugcucuaagucccauuucuguuccaugagauuguuu ---------------------ACUGGACUUGGAGUCAGA----------------------------------------------------------- 1043 0,-2 ---------------------ACUGGACUUGGAGUCAGAu---------------------------------------------------------- 4 0,-2 ---------------------ACUGGACUUGGAGUCAGAA---------------------------------------------------------- 384 0,-1 ---------------------ACUGGACUUGGAGUCAGAAu--------------------------------------------------------- 28 0,-1 ---------------------ACUGGACUUGGAGUCAGAAA--------------------------------------------------------- 515 0,0 ---------------------ACUGGACUUGGAGUCAGAAAA-------------------------------------------------------- 91 0,1 ---------------------ACUGGACUUGGAGUCAGAAAAa------------------------------------------------------- 14 0,1 ----------------------CUGGACUUGGAGUCAGAA---------------------------------------------------------- 5 1,-1 ----------------------CUGGACUUGGAGUCAGAAA--------------------------------------------------------- 5 1,0 >hsa-mir-378e 3pM:58-76 Tumor cugacuccaguguccaggccaggggcagacaguggacagagaacagugcccaagaccACUGGACUUGGAGUCAGGAcau ---------------------------------------------------------ACUGGACUUGGAGUCAGGA--- 16 0,0 ----------------------------------------------------------CUGGACUUGGAGUCAGGA--- 2 1,0 >hsa-mir-378f 3pM:52-71 Tumor gucagguccuggacucccauaguuuucaggcugcuaaacaacagaacgagcACUGGACUUGGAGCCAGAAGucuuggg ---------------------------------------------------ACUGGACUUGGAGCCAGAAG------- 50 0,0 ---------------------------------------------------ACUGGACUUGGAGCCAGAAGg------ 10 0,0 ---------------------------------------------------ACUGGACUUGGAGCCAGAAGU------ 2 0,1 >hsa-mir-378g 5pM:2-21 Tumor cACUGGGCUUGGAGUCAGAAGaccuggcuccagcccagcuc -ACUGGGCUUGGAGUCAGAAG-------------------- 46 0,0 -ACUGGGCUUGGAGUCAGAAGg------------------- 2 0,0 -ACUGGGCUUGGAGUCAGAAGu------------------- 2 0,0 >hsa-mir-379 MA:6-26;mi:44-65 Tumor agagaUGGUAGACUAUGGAACGUAGGcguuaugauuucugaccUAUGUAACAUGGUCCACUAACUcu -----UGGUAGACUAUGGAACGUA------------------------------------------- 2 0,-2 -----UGGUAGACUAUGGAACGUAa------------------------------------------ 4 0,-2 -----UGGUAGACUAUGGAACGUAaa----------------------------------------- 2 0,-2 -----UGGUAGACUAUGGAACGUAG------------------------------------------ 476 0,-1 -----UGGUAGACUAUGGAACGUAGa----------------------------------------- 8 0,-1 -----UGGUAGACUAUGGAACGUAGu----------------------------------------- 2 0,-1 -----UGGUAGACUAUGGAACGUAGG----------------------------------------- 1065 0,0 -----UGGUAGACUAUGGAACGUAGGa---------------------------------------- 303 0,0 -----UGGUAGACUAUGGAACGUAGGaa--------------------------------------- 48 0,0 -----UGGUAGACUAUGGAACGUAGGau--------------------------------------- 3 0,0 -----UGGUAGACUAUGGAACGUAGGu---------------------------------------- 81 0,0 -----UGGUAGACUAUGGAACGUAGGuu--------------------------------------- 2 0,0 -----UGGUAGACUAUGGAACGUAGGC---------------------------------------- 6 0,1 ------GGUAGACUAUGGAACGUAG------------------------------------------ 7 1,-1 ------GGUAGACUAUGGAACGUAGG----------------------------------------- 20 1,0 -------------------------------------------UAUGUAACAUGGUCCACUAA---- 2 0,-2 -------------------------------------------UAUGUAACAUGGUCCACUAAC--- 14 0,-1 >hsa-mir-380 mi:5-26;MA:40-61 Tumor aagaUGGUUGACCAUAGAACAUGCGCuaucucugugucgUAUGUAAUAUGGUCCACAUCUU ---AUGGUUGACCAUAGAACAUGCG------------------------------------ 8 -1,-1 ---------------------------------------UAUGUAAUAUGGUCCACAUCU- 15 0,-1 >hsa-mir-381 3pM:49-70 Tumor uacuuaaagcgagguugcccuuuguauauucgguuuauugacauggaaUAUACAAGGGCAAGCUCUCUGUgagua -------AGCGAGGUUGCCCUUUGUAUAU---------------------------------------------- 2 -------AGCGAGGUUGCCCUUUGUAUAUU--------------------------------------------- 13 -----------------------------------------------AUAUACAAGGGCAAGCUCUCU------- 2 -1,-2 -----------------------------------------------AUAUACAAGGGCAAGCUCUCUGa----- 2 -1,-1 -----------------------------------------------AUAUACAAGGGCAAGCUCUCUGU----- 10 -1,0 ------------------------------------------------UAUACAAGGGCAAGCUCU--------- 2 0,-4 ------------------------------------------------UAUACAAGGGCAAGCUCUC-------- 2 0,-3 ------------------------------------------------UAUACAAGGGCAAGCUCUCU------- 32 0,-2 ------------------------------------------------UAUACAAGGGCAAGCUCUCUG------ 82 0,-1 ------------------------------------------------UAUACAAGGGCAAGCUCUCUGa----- 12 0,-1 ------------------------------------------------UAUACAAGGGCAAGCUCUCUGaa---- 2 0,-1 ------------------------------------------------UAUACAAGGGCAAGCUCUCUGU----- 1118 0,0 ------------------------------------------------UAUACAAGGGCAAGCUCUCUGUa---- 38 0,0 ------------------------------------------------UAUACAAGGGCAAGCUCUCUGUu---- 8 0,0 -------------------------------------------------AUACAAGGGCAAGCUCUCUGU----- 23 1,0 >hsa-mir-382 5pM:11-32 Tumor uacuugaagaGAAGUUGUUCGUGGUGGAUUCGcuuuacuuaugacgaaucauucacggacaacacuuuuuucagua ----------GAAGUUGUUCGUGGUGGAU----------------------------------------------- 33 0,-3 ----------GAAGUUGUUCGUGGUGGAUU---------------------------------------------- 35 0,-2 ----------GAAGUUGUUCGUGGUGGAUUu--------------------------------------------- 2 0,-2 ----------GAAGUUGUUCGUGGUGGAUUC--------------------------------------------- 70 0,-1 ----------GAAGUUGUUCGUGGUGGAUUCa-------------------------------------------- 11 0,-1 ----------GAAGUUGUUCGUGGUGGAUUCu-------------------------------------------- 6 0,-1 ----------GAAGUUGUUCGUGGUGGAUUCG-------------------------------------------- 898 0,0 ----------GAAGUUGUUCGUGGUGGAUUCGa------------------------------------------- 85 0,0 ----------GAAGUUGUUCGUGGUGGAUUCGu------------------------------------------- 26 0,0 -----------AAGUUGUUCGUGGUGGAUU---------------------------------------------- 4 1,-2 -----------AAGUUGUUCGUGGUGGAUUC--------------------------------------------- 2 1,-1 -----------AAGUUGUUCGUGGUGGAUUCG-------------------------------------------- 129 1,0 -----------AAGUUGUUCGUGGUGGAUUCGa------------------------------------------- 6 1,0 ------------AGUUGUUCGUGGUGGAUUCG-------------------------------------------- 4 2,0 ------------AGUUGUUCGUGGUGGAUUCGC------------------------------------------- 10 2,1 ------------AGUUGUUCGUGGUGGAUUCGCU------------------------------------------ 142 2,2 ------------AGUUGUUCGUGGUGGAUUCGCUU----------------------------------------- 2 2,3 ----------------------------------------------AAUCAUUCACGGACAACACU---------- 23 ----------------------------------------------AAUCAUUCACGGACAACACUU--------- 283 ----------------------------------------------AAUCAUUCACGGACAACACUUU-------- 242 ----------------------------------------------AAUCAUUCACGGACAACACUUUU------- 2 >hsa-mir-383 5pM:7-28 Tumor cuccucAGAUCAGAAGGUGAUUGUGGCUuuggguggauauuaaucagccacagcacugccuggucagaaagag ------AGAUCAGAAGGUGAUUGUGGCU--------------------------------------------- 2 0,0 >hsa-mir-3909 3pM:71-92 Tumor gguaugcuguugcgcuguccuuccucuggggagcaggcuccgggggacagggaaaagcacacaaggaacuUGUCCUCUAGGGCCUGCAGUCUcaugggagagugacaugcaccaggacc ---------------------------------------------------------------------UUGUCCUCUAGGGCCUGCAGU----------------------------- 8 -1,-2 ----------------------------------------------------------------------UGUCCUCUAGGGCCUGCAG------------------------------ 2 0,-3 ----------------------------------------------------------------------UGUCCUCUAGGGCCUGCAGU----------------------------- 7 0,-2 ----------------------------------------------------------------------UGUCCUCUAGGGCCUGCAGUC---------------------------- 21 0,-1 ----------------------------------------------------------------------UGUCCUCUAGGGCCUGCAGUCa--------------------------- 5 0,-1 ----------------------------------------------------------------------UGUCCUCUAGGGCCUGCAGUCU--------------------------- 77 0,0 ----------------------------------------------------------------------UGUCCUCUAGGGCCUGCAGUCUu-------------------------- 2 0,0 -----------------------------------------------------------------------GUCCUCUAGGGCCUGCAGU----------------------------- 3 1,-2 >hsa-mir-3910-1 3pM:63-82 Tumor cuuuugcugucaguuuuucuguugcuugucuugguuuuaugccuuuuauaucaaggcacauaAAAGGCAUAAAACCAAGACAagcaacaaaaaaaggauugaucacagaag -------------------------------------------------------------AAAAGGCAUAAAACCAAGACA----------------------------- 2 -1,0 --------------------------------------------------------------AAAGGCAUAAAACCAAGACAA---------------------------- 8 0,1 >hsa-mir-3910-2 3pM:50-69 Tumor uuuuuuuguugcuugucuugguuuuaugccuuuuaugugccuugauauaAAAGGCAUAAAACCAAGACAagcaacagaaaaa ------------------------------------------------AAAAGGCAUAAAACCAAGACA------------- 2 -1,0 -------------------------------------------------AAAGGCAUAAAACCAAGACAA------------ 8 0,1 >hsa-mir-3912 3pM:63-83 Tumor agagaggaaugaacaguuaaauuauaacauguccauauuauggguuaguuguggacacauacUAACGCAUAAUAUGGACAUGUuauaauuuaacuguuccuuucu --------------------------------------------------------------UAACGCAUAAUAUGGACAUG----------------------- 2 0,-1 --------------------------------------------------------------UAACGCAUAAUAUGGACAUGU---------------------- 10 0,0 --------------------------------------------------------------UAACGCAUAAUAUGGACAUGUU--------------------- 10 0,1 ---------------------------------------------------------------AACGCAUAAUAUGGACAUGUU--------------------- 2 1,1 ----------------------------------------------------------------ACGCAUAAUAUGGACAUGUUAU------------------- 2 2,3 >hsa-mir-3913-1 5p:23-44;3p:59-80 Tumor uuguuuauaauaaacugaaauaUUUGGGACUGAUCUUGAUGUCUgccaaaaccuuggcAGACAUCAAGAUCAGUCCCAAAuauuucaguuuauuauagacag ---------------------AUUUGGGACUGAUCUUGAg-------------------------------------------------------------- 2 -1,-5 ---------------------AUUUGGGACUGAUCUUGAUGUC----------------------------------------------------------- 2 -1,-1 ----------------------UUUGGGACUGAUCUUGAUGUC----------------------------------------------------------- 4 0,-1 ----------------------UUUGGGACUGAUCUUGAUGUCU---------------------------------------------------------- 47 0,0 -----------------------UUGGGACUGAUCUUGAUGUCU---------------------------------------------------------- 26 1,0 -----------------------UUGGGACUGAUCUUGAUGUCUG--------------------------------------------------------- 3 1,1 ------------------------UGGGACUGAUCUUGAUGUCU---------------------------------------------------------- 6 2,0 ------------------------UGGGACUGAUCUUGAUGUCUG--------------------------------------------------------- 8 2,1 ------------------------UGGGACUGAUCUUGAUGUCUGC-------------------------------------------------------- 8 2,2 >hsa-mir-3913-2 5pM:22-43 Tumor ugucuauaauaaacugaaauaUUUGGGACUGAUCUUGAUGUCUgccaagguuuuggcagacaucaagaucagucccaaauauuucaguuuauuauaaaca --------------------AUUUGGGACUGAUCUUGAg------------------------------------------------------------- 2 -1,-5 --------------------AUUUGGGACUGAUCUUGAUGUC---------------------------------------------------------- 2 -1,-1 ---------------------UUUGGGACUGAUCUUGAUGUC---------------------------------------------------------- 4 0,-1 ---------------------UUUGGGACUGAUCUUGAUGUCU--------------------------------------------------------- 47 0,0 ----------------------UUGGGACUGAUCUUGAUGUCU--------------------------------------------------------- 26 1,0 ----------------------UUGGGACUGAUCUUGAUGUCUG-------------------------------------------------------- 3 1,1 -----------------------UGGGACUGAUCUUGAUGUCU--------------------------------------------------------- 6 2,0 -----------------------UGGGACUGAUCUUGAUGUCUG-------------------------------------------------------- 8 2,1 -----------------------UGGGACUGAUCUUGAUGUCUGC------------------------------------------------------- 8 2,2 >hsa-mir-3927 3pM:45-66 Tumor ugccaaugccuaucacauaucugccuguccuaugacaaacauggCAGGUAGAUAUUUGAUAGGCAUuggca --------------------------------------------CAGGUAGAUAUUUGAUAGGCAU----- 2 0,0 >hsa-mir-3928 3pM:37-58 Tumor gcugaagcucuaagguuccgccugcgggcaggaagcGGAGGAACCUUGGAGCUUCGGC ------------------------------------GGAGGAACCUUGGAGCUUCGG- 9 0,-1 ------------------------------------GGAGGAACCUUGGAGCUUCGGu 4 0,-1 --------------------------------------AGGAACCUUGGAGCUUCGGC 2 2,0 >hsa-mir-3934 5pM:25-46 Tumor cacagcccuuccuguccccaguuuUCAGGUGUGGAAACUGAGGCAGgaggcagugaaguaacuugcucagguugcacagcugggaaguggagcagggauuugaaucc ------------------------UCAGGUGUGGAAACUGAGGCA-------------------------------------------------------------- 2 0,-1 ------------------------UCAGGUGUGGAAACUGAGGCAa------------------------------------------------------------- 2 0,-1 ------------------------UCAGGUGUGGAAACUGAGGCAG------------------------------------------------------------- 4 0,0 >hsa-mir-3940 5p:23-42;3p:57-78 Tumor gcuuaucgaggaaaagaucgagGUGGGUUGGGGCGGGCUCUGgggauuuggucucaCAGCCCGGAUCCCAGCCCACUUaccuugguuacucuccuuccuucu --------------------------------------------------------CAGCCCGGAUCCCAGCCCACU------------------------- 15 0,-1 --------------------------------------------------------CAGCCCGGAUCCCAGCCCACUU------------------------ 4 0,0 >hsa-mir-3942 5p:23-44;3p:65-85 Tumor ucuucaguaugacaccucaaagAAGCAAUACUGUUACCUGAAAUaggcugcgaagauaacaguaUUUCAGAUAACAGUAUUACAUcuuugaagugucauauucacugac ----------------------------------------------------------------UUUCAGAUAACAGUAUUACAU------------------------ 2 0,0 >hsa-mir-3943 5pM:23-45 Tumor cacacagacggcagcugcggccUAGCCCCCAGGCUUCACUUGGCGuggacaacuugcuaaguaaaguggggggugggccacggcuggcuccuaccuggac ----------------------UAGCCCCCAGGCUUCACUUGGC-------------------------------------------------------- 2 0,-1 >hsa-mir-409 5p:15-37;3p:47-68 Tumor ugguacucggggagAGGUUACCCGAGCAACUUUGCAUcuggacgacGAAUGUUGCUCGGUGAACCCCUuuucgguauca --------------AGGUUACCCGAGCAACUUUG--------------------------------------------- 13 0,-3 --------------AGGUUACCCGAGCAACUUUGC-------------------------------------------- 92 0,-2 --------------AGGUUACCCGAGCAACUUUGCA------------------------------------------- 234 0,-1 --------------AGGUUACCCGAGCAACUUUGCAa------------------------------------------ 3 0,-1 --------------AGGUUACCCGAGCAACUUUGCAU------------------------------------------ 295 0,0 --------------AGGUUACCCGAGCAACUUUGCAUC----------------------------------------- 57 0,1 ---------------GGUUACCCGAGCAACUUUGCA------------------------------------------- 4 1,-1 ---------------------------------------------CGAAUGUUGCUCGGUGAA---------------- 2 -1,-5 ---------------------------------------------CGAAUGUUGCUCGGUGAAa--------------- 4 -1,-5 ---------------------------------------------CGAAUGUUGCUCGGUGAAC--------------- 45 -1,-4 ---------------------------------------------CGAAUGUUGCUCGGUGAACC-------------- 43 -1,-3 ---------------------------------------------CGAAUGUUGCUCGGUGAACCC------------- 11 -1,-2 ---------------------------------------------CGAAUGUUGCUCGGUGAACCCC------------ 48 -1,-1 ---------------------------------------------CGAAUGUUGCUCGGUGAACCCCa----------- 6 -1,-1 ---------------------------------------------CGAAUGUUGCUCGGUGAACCCCU----------- 460 -1,0 ---------------------------------------------CGAAUGUUGCUCGGUGAACCCCUa---------- 8 -1,0 ---------------------------------------------CGAAUGUUGCUCGGUGAACCCCUau--------- 2 -1,0 ---------------------------------------------CGAAUGUUGCUCGGUGAACCCCUU---------- 72 -1,1 ---------------------------------------------CGAAUGUUGCUCGGUGAACCCCUUU--------- 8 -1,2 ----------------------------------------------GAAUGUUGCUCGGUGAAC--------------- 12 0,-4 ----------------------------------------------GAAUGUUGCUCGGUGAACC-------------- 14 0,-3 ----------------------------------------------GAAUGUUGCUCGGUGAACCC------------- 14 0,-2 ----------------------------------------------GAAUGUUGCUCGGUGAACCCuu----------- 3 0,-2 ----------------------------------------------GAAUGUUGCUCGGUGAACCCC------------ 87 0,-1 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCa----------- 8 0,-1 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCU----------- 1031 0,0 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCUa---------- 16 0,0 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCUaa--------- 2 0,0 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCUau--------- 4 0,0 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCUU---------- 89 0,1 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCUUU--------- 14 0,2 ----------------------------------------------GAAUGUUGCUCGGUGAACCCCUUUU-------- 2 0,3 -----------------------------------------------AAUGUUGCUCGGUGAACCC------------- 2 1,-2 -----------------------------------------------AAUGUUGCUCGGUGAACCCC------------ 4 1,-1 -----------------------------------------------AAUGUUGCUCGGUGAACCCCU----------- 62 1,0 -----------------------------------------------AAUGUUGCUCGGUGAACCCCUUU--------- 2 1,2 >hsa-mir-410 3pM:50-70 Tumor gguaccugagaagagguugucugugaugaguucgcuuuuauuaaugacgAAUAUAACACAGAUGGCCUGUuuucaguacc -------------------------------------------------AAUAUAACACAGAUGGCCUGa---------- 2 0,-1 -------------------------------------------------AAUAUAACACAGAUGGCCUGU---------- 364 0,0 -------------------------------------------------AAUAUAACACAGAUGGCCUGUa--------- 8 0,0 -------------------------------------------------AAUAUAACACAGAUGGCCUGUU--------- 2 0,1 >hsa-mir-411 MA:16-36;mi:51-72 Tumor ugguacuuggagagaUAGUAGACCGUAUAGCGUACGcuuuaucugugacgUAUGUAACACGGUCCACUAACCcucaguaucaaauccauccccgag --------------AUAGUAGACCGUAUAGCGUAa------------------------------------------------------------- 10 -1,-2 --------------AUAGUAGACCGUAUAGCGUAC------------------------------------------------------------- 98 -1,-1 --------------AUAGUAGACCGUAUAGCGUACG------------------------------------------------------------ 634 -1,0 --------------AUAGUAGACCGUAUAGCGUACGa----------------------------------------------------------- 27 -1,0 ---------------UAGUAGACCGUAUAGCGUA-------------------------------------------------------------- 2 0,-2 ---------------UAGUAGACCGUAUAGCGUAC------------------------------------------------------------- 62 0,-1 ---------------UAGUAGACCGUAUAGCGUACu------------------------------------------------------------ 2 0,-1 ---------------UAGUAGACCGUAUAGCGUACG------------------------------------------------------------ 508 0,0 ---------------UAGUAGACCGUAUAGCGUACGa----------------------------------------------------------- 16 0,0 ---------------UAGUAGACCGUAUAGCGUACGu----------------------------------------------------------- 2 0,0 ----------------AGUAGACCGUAUAGCGUACG------------------------------------------------------------ 9 1,0 --------------------------------------------------UAUGUAACACGGUCCACUAA-------------------------- 2 0,-2 --------------------------------------------------UAUGUAACACGGUCCACUAAu------------------------- 2 0,-2 --------------------------------------------------UAUGUAACACGGUCCACUAAC------------------------- 37 0,-1 --------------------------------------------------UAUGUAACACGGUCCACUAACC------------------------ 2 0,0 >hsa-mir-412 3pM:54-76 Tumor cugggguacggggauggauggucgaccaguuggaaaguaauuguuucuaauguACUUCACCUGGUCCACUAGCCGUccguauccgcugcag ------------------UGGUCGACCAGUUGGAAAGU----------------------------------------------------- 2 ------------------UGGUCGACCAGUUGGAAAGUAA--------------------------------------------------- 2 ------------------UGGUCGACCAGUUGGAAAGUAAU-------------------------------------------------- 6 ------------------------------------------------------CUUCACCUGGUCCACUAGCau---------------- 2 1,-3 >hsa-mir-421 3pM:48-70 Tumor gcacauuguaggccucauuaaauguuuguugaaugaaaaaaugaaucAUCAACAGACAUUAAUUGGGCGCcugcucugugaucuc -------------CUCAUUAAAUGUUUGUUGAAU--------------------------------------------------- 4 -----------------------------------------------AUCAACAGACAUUAAUUGG------------------- 2 0,-4 -----------------------------------------------AUCAACAGACAUUAAUUGGG------------------ 5 0,-3 -----------------------------------------------AUCAACAGACAUUAAUUGGGa----------------- 8 0,-3 -----------------------------------------------AUCAACAGACAUUAAUUGGGC----------------- 157 0,-2 -----------------------------------------------AUCAACAGACAUUAAUUGGGCa---------------- 4 0,-2 -----------------------------------------------AUCAACAGACAUUAAUUGGGCu---------------- 3 0,-2 -----------------------------------------------AUCAACAGACAUUAAUUGGGCG---------------- 406 0,-1 -----------------------------------------------AUCAACAGACAUUAAUUGGGCGa--------------- 111 0,-1 -----------------------------------------------AUCAACAGACAUUAAUUGGGCGau-------------- 3 0,-1 -----------------------------------------------AUCAACAGACAUUAAUUGGGCGu--------------- 182 0,-1 -----------------------------------------------AUCAACAGACAUUAAUUGGGCGuu-------------- 7 0,-1 -----------------------------------------------AUCAACAGACAUUAAUUGGGCGC--------------- 418 0,0 -----------------------------------------------AUCAACAGACAUUAAUUGGGCGCa-------------- 2 0,0 -----------------------------------------------AUCAACAGACAUUAAUUGGGCGCau------------- 2 0,0 -----------------------------------------------AUCAACAGACAUUAAUUGGGCGCu-------------- 9 0,0 -------------------------------------------------CAACAGACAUUAAUUGGGCG---------------- 2 2,-1 >hsa-mir-423 5p:17-39;3p:53-75 Tumor auaaaggaaguuaggcUGAGGGGCAGAGAGCGAGACUUUucuauuuuccaaaAGCUCGGUCUGAGGCCCCUCAGUcuugcuuccuaacccgcgc ---------------CUGAGGGGCAGAGAGCGAGA----------------------------------------------------------- 2 -1,-4 ---------------CUGAGGGGCAGAGAGCGAGAC---------------------------------------------------------- 2 -1,-3 ---------------CUGAGGGGCAGAGAGCGAGACU--------------------------------------------------------- 5 -1,-2 ---------------CUGAGGGGCAGAGAGCGAGACUUU------------------------------------------------------- 46 -1,0 ---------------CUGAGGGGCAGAGAGCGAGACUUUU------------------------------------------------------ 4 -1,1 ----------------UGAGGGGCAGAGAGCGAG------------------------------------------------------------ 201 0,-5 ----------------UGAGGGGCAGAGAGCGAGu----------------------------------------------------------- 21 0,-5 ----------------UGAGGGGCAGAGAGCGAGA----------------------------------------------------------- 1284 0,-4 ----------------UGAGGGGCAGAGAGCGAGAa---------------------------------------------------------- 218 0,-4 ----------------UGAGGGGCAGAGAGCGAGAaa--------------------------------------------------------- 283 0,-4 ----------------UGAGGGGCAGAGAGCGAGAau--------------------------------------------------------- 31 0,-4 ----------------UGAGGGGCAGAGAGCGAGAu---------------------------------------------------------- 30 0,-4 ----------------UGAGGGGCAGAGAGCGAGAuu--------------------------------------------------------- 2 0,-4 ----------------UGAGGGGCAGAGAGCGAGAC---------------------------------------------------------- 870 0,-3 ----------------UGAGGGGCAGAGAGCGAGACa--------------------------------------------------------- 249 0,-3 ----------------UGAGGGGCAGAGAGCGAGACaa-------------------------------------------------------- 26 0,-3 ----------------UGAGGGGCAGAGAGCGAGACc--------------------------------------------------------- 3 0,-3 ----------------UGAGGGGCAGAGAGCGAGACg--------------------------------------------------------- 3 0,-3 ----------------UGAGGGGCAGAGAGCGAGACU--------------------------------------------------------- 3295 0,-2 ----------------UGAGGGGCAGAGAGCGAGACUa-------------------------------------------------------- 8 0,-2 ----------------UGAGGGGCAGAGAGCGAGACUaa------------------------------------------------------- 29 0,-2 ----------------UGAGGGGCAGAGAGCGAGACUau------------------------------------------------------- 4 0,-2 ----------------UGAGGGGCAGAGAGCGAGACUU-------------------------------------------------------- 1778 0,-1 ----------------UGAGGGGCAGAGAGCGAGACUUa------------------------------------------------------- 174 0,-1 ----------------UGAGGGGCAGAGAGCGAGACUUaa------------------------------------------------------ 6 0,-1 ----------------UGAGGGGCAGAGAGCGAGACUUau------------------------------------------------------ 12 0,-1 ----------------UGAGGGGCAGAGAGCGAGACUUc------------------------------------------------------- 8 0,-1 ----------------UGAGGGGCAGAGAGCGAGACUUg------------------------------------------------------- 4 0,-1 ----------------UGAGGGGCAGAGAGCGAGACUUU------------------------------------------------------- 12742 0,0 ----------------UGAGGGGCAGAGAGCGAGACUUUa------------------------------------------------------ 157 0,0 ----------------UGAGGGGCAGAGAGCGAGACUUUaa----------------------------------------------------- 8 0,0 ----------------UGAGGGGCAGAGAGCGAGACUUUau----------------------------------------------------- 6 0,0 ----------------UGAGGGGCAGAGAGCGAGACUUUg------------------------------------------------------ 8 0,0 ----------------UGAGGGGCAGAGAGCGAGACUUUU------------------------------------------------------ 2488 0,1 ----------------UGAGGGGCAGAGAGCGAGACUUUUa----------------------------------------------------- 2 0,1 ----------------UGAGGGGCAGAGAGCGAGACUUUUu----------------------------------------------------- 67 0,1 ----------------UGAGGGGCAGAGAGCGAGACUUUUC----------------------------------------------------- 2 0,2 -----------------GAGGGGCAGAGAGCGAGA----------------------------------------------------------- 25 1,-4 -----------------GAGGGGCAGAGAGCGAGAa---------------------------------------------------------- 2 1,-4 -----------------GAGGGGCAGAGAGCGAGAaa--------------------------------------------------------- 2 1,-4 -----------------GAGGGGCAGAGAGCGAGAC---------------------------------------------------------- 13 1,-3 -----------------GAGGGGCAGAGAGCGAGACU--------------------------------------------------------- 68 1,-2 -----------------GAGGGGCAGAGAGCGAGACUU-------------------------------------------------------- 52 1,-1 -----------------GAGGGGCAGAGAGCGAGACUUa------------------------------------------------------- 2 1,-1 -----------------GAGGGGCAGAGAGCGAGACUUU------------------------------------------------------- 435 1,0 -----------------GAGGGGCAGAGAGCGAGACUUUa------------------------------------------------------ 2 1,0 -----------------GAGGGGCAGAGAGCGAGACUUUU------------------------------------------------------ 83 1,1 ------------------AGGGGCAGAGAGCGAGACU--------------------------------------------------------- 2 2,-2 ------------------AGGGGCAGAGAGCGAGACUU-------------------------------------------------------- 2 2,-1 ------------------AGGGGCAGAGAGCGAGACUUU------------------------------------------------------- 24 2,0 ------------------AGGGGCAGAGAGCGAGACUUUU------------------------------------------------------ 70 2,1 --------------------------------------------------AAAGCUCGGUCUGAGGCCCCU----------------------- 2 -2,-4 --------------------------------------------------AAAGCUCGGUCUGAGGCCCCUu---------------------- 7 -2,-4 ---------------------------------------------------AAGCUCGGUCUGAGGCCCC------------------------ 105 -1,-5 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCU----------------------- 345 -1,-4 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUa---------------------- 4 -1,-4 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUaa--------------------- 4 -1,-4 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUu---------------------- 64 -1,-4 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUuu--------------------- 37 -1,-4 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUC---------------------- 529 -1,-3 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCc--------------------- 2 -1,-3 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCu--------------------- 42 -1,-3 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCuu-------------------- 6 -1,-3 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCA--------------------- 453 -1,-2 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAa-------------------- 28 -1,-2 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAaa------------------- 7 -1,-2 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAau------------------- 21 -1,-2 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAu-------------------- 79 -1,-2 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAuu------------------- 18 -1,-2 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAG-------------------- 669 -1,-1 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAGa------------------- 145 -1,-1 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAGaa------------------ 2 -1,-1 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAGau------------------ 4 -1,-1 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAGc------------------- 13 -1,-1 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAGg------------------- 13 -1,-1 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAGU------------------- 5006 -1,0 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAGUa------------------ 34 -1,0 ---------------------------------------------------AAGCUCGGUCUGAGGCCCCUCAGUu------------------ 236 -1,0 ----------------------------------------------------AGCUCGGUCUGAGGCCCC------------------------ 198 0,-5 ----------------------------------------------------AGCUCGGUCUGAGGCCCCaa---------------------- 2 0,-5 ----------------------------------------------------AGCUCGGUCUGAGGCCCCU----------------------- 953 0,-4 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUa---------------------- 20 0,-4 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUaa--------------------- 33 0,-4 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUau--------------------- 21 0,-4 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUu---------------------- 119 0,-4 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUuu--------------------- 120 0,-4 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUC---------------------- 3467 0,-3 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCc--------------------- 20 0,-3 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCu--------------------- 128 0,-3 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCuu-------------------- 7 0,-3 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCA--------------------- 1785 0,-2 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAa-------------------- 210 0,-2 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAaa------------------- 169 0,-2 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAau------------------- 194 0,-2 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAu-------------------- 225 0,-2 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAuu------------------- 115 0,-2 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAG-------------------- 4147 0,-1 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGa------------------- 1348 0,-1 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGaa------------------ 250 0,-1 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGau------------------ 119 0,-1 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGc------------------- 309 0,-1 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGg------------------- 118 0,-1 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGU------------------- 45950 0,0 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGUa------------------ 1678 0,0 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGUaa----------------- 238 0,0 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGUau----------------- 342 0,0 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGUg------------------ 31 0,0 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGUu------------------ 4332 0,0 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGUuu----------------- 735 0,0 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGUC------------------ 9 0,1 ----------------------------------------------------AGCUCGGUCUGAGGCCCCUCAGUCU----------------- 2 0,2 -----------------------------------------------------GCUCGGUCUGAGGCCCCU----------------------- 7 1,-4 -----------------------------------------------------GCUCGGUCUGAGGCCCCUuu--------------------- 3 1,-4 -----------------------------------------------------GCUCGGUCUGAGGCCCCUC---------------------- 67 1,-3 -----------------------------------------------------GCUCGGUCUGAGGCCCCUCA--------------------- 8 1,-2 -----------------------------------------------------GCUCGGUCUGAGGCCCCUCAa-------------------- 2 1,-2 -----------------------------------------------------GCUCGGUCUGAGGCCCCUCAuu------------------- 2 1,-2 -----------------------------------------------------GCUCGGUCUGAGGCCCCUCAG-------------------- 71 1,-1 -----------------------------------------------------GCUCGGUCUGAGGCCCCUCAGa------------------- 12 1,-1 -----------------------------------------------------GCUCGGUCUGAGGCCCCUCAGU------------------- 839 1,0 -----------------------------------------------------GCUCGGUCUGAGGCCCCUCAGUa------------------ 14 1,0 -----------------------------------------------------GCUCGGUCUGAGGCCCCUCAGUu------------------ 57 1,0 -----------------------------------------------------GCUCGGUCUGAGGCCCCUCAGUuu----------------- 2 1,0 ------------------------------------------------------CUCGGUCUGAGGCCCCUCAGU------------------- 6 2,0 ------------------------------------------------------CUCGGUCUGAGGCCCCUCAGUu------------------ 4 2,0 ------------------------------------------------------CUCGGUCUGAGGCCCCUCAGUuu----------------- 5 2,0 >hsa-mir-424 MA:11-32;mi:48-68 Tumor cgaggggauaCAGCAGCAAUUCAUGUUUUGAAguguucuaaaugguuCAAAACGUGAGGCGCUGCUAUacccccucguggggaagguagaaggugggg ---------ACAGCAGCAAUUCAUGUUUU--------------------------------------------------------------------- 6 -1,-3 ---------ACAGCAGCAAUUCAUGUUUUG-------------------------------------------------------------------- 18 -1,-2 ---------ACAGCAGCAAUUCAUGUUUUGA------------------------------------------------------------------- 325 -1,-1 ---------ACAGCAGCAAUUCAUGUUUUGAA------------------------------------------------------------------ 6 -1,0 ----------CAGCAGCAAUUCAUGUUU---------------------------------------------------------------------- 286 0,-4 ----------CAGCAGCAAUUCAUGUUUg--------------------------------------------------------------------- 2 0,-4 ----------CAGCAGCAAUUCAUGUUUU--------------------------------------------------------------------- 1768 0,-3 ----------CAGCAGCAAUUCAUGUUUUa-------------------------------------------------------------------- 36 0,-3 ----------CAGCAGCAAUUCAUGUUUUaa------------------------------------------------------------------- 138 0,-3 ----------CAGCAGCAAUUCAUGUUUUu-------------------------------------------------------------------- 47 0,-3 ----------CAGCAGCAAUUCAUGUUUUG-------------------------------------------------------------------- 6483 0,-2 ----------CAGCAGCAAUUCAUGUUUUGc------------------------------------------------------------------- 142 0,-2 ----------CAGCAGCAAUUCAUGUUUUGg------------------------------------------------------------------- 51 0,-2 ----------CAGCAGCAAUUCAUGUUUUGu------------------------------------------------------------------- 189 0,-2 ----------CAGCAGCAAUUCAUGUUUUGA------------------------------------------------------------------- 76510 0,-1 ----------CAGCAGCAAUUCAUGUUUUGAc------------------------------------------------------------------ 146 0,-1 ----------CAGCAGCAAUUCAUGUUUUGAg------------------------------------------------------------------ 53 0,-1 ----------CAGCAGCAAUUCAUGUUUUGAu------------------------------------------------------------------ 151 0,-1 ----------CAGCAGCAAUUCAUGUUUUGAuu----------------------------------------------------------------- 2 0,-1 ----------CAGCAGCAAUUCAUGUUUUGAA------------------------------------------------------------------ 19063 0,0 ----------CAGCAGCAAUUCAUGUUUUGAAa----------------------------------------------------------------- 3772 0,0 ----------CAGCAGCAAUUCAUGUUUUGAAaa---------------------------------------------------------------- 71 0,0 ----------CAGCAGCAAUUCAUGUUUUGAAau---------------------------------------------------------------- 6 0,0 ----------CAGCAGCAAUUCAUGUUUUGAAc----------------------------------------------------------------- 57 0,0 ----------CAGCAGCAAUUCAUGUUUUGAAu----------------------------------------------------------------- 1529 0,0 ----------CAGCAGCAAUUCAUGUUUUGAAuu---------------------------------------------------------------- 4 0,0 ----------CAGCAGCAAUUCAUGUUUUGAAG----------------------------------------------------------------- 91 0,1 -----------AGCAGCAAUUCAUGUUUU--------------------------------------------------------------------- 16 1,-3 -----------AGCAGCAAUUCAUGUUUUG-------------------------------------------------------------------- 191 1,-2 -----------AGCAGCAAUUCAUGUUUUGA------------------------------------------------------------------- 2524 1,-1 -----------AGCAGCAAUUCAUGUUUUGAu------------------------------------------------------------------ 2 1,-1 -----------AGCAGCAAUUCAUGUUUUGAA------------------------------------------------------------------ 822 1,0 -----------AGCAGCAAUUCAUGUUUUGAAa----------------------------------------------------------------- 145 1,0 -----------AGCAGCAAUUCAUGUUUUGAAaa---------------------------------------------------------------- 2 1,0 -----------AGCAGCAAUUCAUGUUUUGAAu----------------------------------------------------------------- 46 1,0 -----------AGCAGCAAUUCAUGUUUUGAAG----------------------------------------------------------------- 2 1,1 -----------------------------------------------CAAAACGUGAGGCGCUGC--------------------------------- 3 0,-3 -----------------------------------------------CAAAACGUGAGGCGCUGCU-------------------------------- 52 0,-2 -----------------------------------------------CAAAACGUGAGGCGCUGCUu------------------------------- 2 0,-2 -----------------------------------------------CAAAACGUGAGGCGCUGCUuu------------------------------ 2 0,-2 -----------------------------------------------CAAAACGUGAGGCGCUGCUA------------------------------- 83 0,-1 -----------------------------------------------CAAAACGUGAGGCGCUGCUAa------------------------------ 11 0,-1 -----------------------------------------------CAAAACGUGAGGCGCUGCUAU------------------------------ 877 0,0 -----------------------------------------------CAAAACGUGAGGCGCUGCUAUu----------------------------- 34 0,0 -----------------------------------------------CAAAACGUGAGGCGCUGCUAUA----------------------------- 285 0,1 -----------------------------------------------CAAAACGUGAGGCGCUGCUAUAa---------------------------- 47 0,1 -----------------------------------------------CAAAACGUGAGGCGCUGCUAUAu---------------------------- 25 0,1 ------------------------------------------------AAAACGUGAGGCGCUGCU-------------------------------- 4 1,-2 ------------------------------------------------AAAACGUGAGGCGCUGCUAU------------------------------ 22 1,0 ------------------------------------------------AAAACGUGAGGCGCUGCUAUu----------------------------- 4 1,0 ------------------------------------------------AAAACGUGAGGCGCUGCUAUA----------------------------- 16 1,1 ------------------------------------------------AAAACGUGAGGCGCUGCUAUAC---------------------------- 2 1,2 >hsa-mir-425 MA:14-36;mi:55-76 Tumor gaaagcgcuuuggAAUGACACGAUCACUCCCGUUGAgugggcacccgagaagccAUCGGGAAUGUCGUGUCCGCCCagugcucuuuc -------------AAUGACACGAUCACUCCC-------------------------------------------------------- 162 0,-5 -------------AAUGACACGAUCACUCCCG------------------------------------------------------- 519 0,-4 -------------AAUGACACGAUCACUCCCGa------------------------------------------------------ 4 0,-4 -------------AAUGACACGAUCACUCCCGc------------------------------------------------------ 2 0,-4 -------------AAUGACACGAUCACUCCCGU------------------------------------------------------ 755 0,-3 -------------AAUGACACGAUCACUCCCGUa----------------------------------------------------- 5 0,-3 -------------AAUGACACGAUCACUCCCGUaa---------------------------------------------------- 11 0,-3 -------------AAUGACACGAUCACUCCCGUU----------------------------------------------------- 6038 0,-2 -------------AAUGACACGAUCACUCCCGUUa---------------------------------------------------- 331 0,-2 -------------AAUGACACGAUCACUCCCGUUaa--------------------------------------------------- 50 0,-2 -------------AAUGACACGAUCACUCCCGUUau--------------------------------------------------- 11 0,-2 -------------AAUGACACGAUCACUCCCGUUc---------------------------------------------------- 4 0,-2 -------------AAUGACACGAUCACUCCCGUUu---------------------------------------------------- 313 0,-2 -------------AAUGACACGAUCACUCCCGUUuu--------------------------------------------------- 2 0,-2 -------------AAUGACACGAUCACUCCCGUUG---------------------------------------------------- 21053 0,-1 -------------AAUGACACGAUCACUCCCGUUGc--------------------------------------------------- 181 0,-1 -------------AAUGACACGAUCACUCCCGUUGg--------------------------------------------------- 14 0,-1 -------------AAUGACACGAUCACUCCCGUUGu--------------------------------------------------- 2692 0,-1 -------------AAUGACACGAUCACUCCCGUUGuu-------------------------------------------------- 30 0,-1 -------------AAUGACACGAUCACUCCCGUUGA--------------------------------------------------- 21770 0,0 -------------AAUGACACGAUCACUCCCGUUGAa-------------------------------------------------- 697 0,0 -------------AAUGACACGAUCACUCCCGUUGAaa------------------------------------------------- 23 0,0 -------------AAUGACACGAUCACUCCCGUUGAau------------------------------------------------- 44 0,0 -------------AAUGACACGAUCACUCCCGUUGAc-------------------------------------------------- 6 0,0 -------------AAUGACACGAUCACUCCCGUUGAu-------------------------------------------------- 363 0,0 -------------AAUGACACGAUCACUCCCGUUGAuu------------------------------------------------- 32 0,0 -------------AAUGACACGAUCACUCCCGUUGAG-------------------------------------------------- 9837 0,1 -------------AAUGACACGAUCACUCCCGUUGAGa------------------------------------------------- 646 0,1 -------------AAUGACACGAUCACUCCCGUUGAGc------------------------------------------------- 57 0,1 -------------AAUGACACGAUCACUCCCGUUGAGg------------------------------------------------- 33 0,1 -------------AAUGACACGAUCACUCCCGUUGAGU------------------------------------------------- 19244 0,2 --------------AUGACACGAUCACUCCCG------------------------------------------------------- 13 1,-4 --------------AUGACACGAUCACUCCCGU------------------------------------------------------ 10 1,-3 --------------AUGACACGAUCACUCCCGUU----------------------------------------------------- 190 1,-2 --------------AUGACACGAUCACUCCCGUUa---------------------------------------------------- 9 1,-2 --------------AUGACACGAUCACUCCCGUUaa--------------------------------------------------- 2 1,-2 --------------AUGACACGAUCACUCCCGUUu---------------------------------------------------- 11 1,-2 --------------AUGACACGAUCACUCCCGUUG---------------------------------------------------- 665 1,-1 --------------AUGACACGAUCACUCCCGUUGc--------------------------------------------------- 2 1,-1 --------------AUGACACGAUCACUCCCGUUGu--------------------------------------------------- 97 1,-1 --------------AUGACACGAUCACUCCCGUUGuu-------------------------------------------------- 2 1,-1 --------------AUGACACGAUCACUCCCGUUGA--------------------------------------------------- 1604 1,0 --------------AUGACACGAUCACUCCCGUUGAa-------------------------------------------------- 133 1,0 --------------AUGACACGAUCACUCCCGUUGAaa------------------------------------------------- 8 1,0 --------------AUGACACGAUCACUCCCGUUGAau------------------------------------------------- 10 1,0 --------------AUGACACGAUCACUCCCGUUGAu-------------------------------------------------- 46 1,0 --------------AUGACACGAUCACUCCCGUUGAuu------------------------------------------------- 8 1,0 --------------AUGACACGAUCACUCCCGUUGAG-------------------------------------------------- 2773 1,1 --------------AUGACACGAUCACUCCCGUUGAGa------------------------------------------------- 399 1,1 --------------AUGACACGAUCACUCCCGUUGAGau------------------------------------------------ 3 1,1 --------------AUGACACGAUCACUCCCGUUGAGc------------------------------------------------- 10 1,1 --------------AUGACACGAUCACUCCCGUUGAGg------------------------------------------------- 7 1,1 --------------AUGACACGAUCACUCCCGUUGAGU------------------------------------------------- 5421 1,2 --------------AUGACACGAUCACUCCCGUUGAGUa------------------------------------------------ 18 1,2 --------------AUGACACGAUCACUCCCGUUGAGUu------------------------------------------------ 133 1,2 ---------------UGACACGAUCACUCCCGUU----------------------------------------------------- 2 2,-2 ---------------UGACACGAUCACUCCCGUUG---------------------------------------------------- 3 2,-1 ---------------UGACACGAUCACUCCCGUUGA--------------------------------------------------- 11 2,0 ---------------UGACACGAUCACUCCCGUUGAG-------------------------------------------------- 73 2,1 ---------------UGACACGAUCACUCCCGUUGAGa------------------------------------------------- 15 2,1 ---------------UGACACGAUCACUCCCGUUGAGU------------------------------------------------- 341 2,2 ---------------UGACACGAUCACUCCCGUUGAGUau----------------------------------------------- 2 2,2 ---------------UGACACGAUCACUCCCGUUGAGUu------------------------------------------------ 2 2,2 ----------------------------------------------------CCAUCGGGAAUGUCGUGUCa--------------- 4 -2,-5 ----------------------------------------------------CCAUCGGGAAUGUCGUGUCC--------------- 5 -2,-4 ----------------------------------------------------CCAUCGGGAAUGUCGUGUCCG-------------- 14 -2,-3 ----------------------------------------------------CCAUCGGGAAUGUCGUGUCCGa------------- 4 -2,-3 ----------------------------------------------------CCAUCGGGAAUGUCGUGUCCGu------------- 34 -2,-3 ----------------------------------------------------CCAUCGGGAAUGUCGUGUCCGuu------------ 5 -2,-3 ----------------------------------------------------CCAUCGGGAAUGUCGUGUCCGC------------- 35 -2,-2 ----------------------------------------------------CCAUCGGGAAUGUCGUGUCCGCC------------ 2 -2,-1 -----------------------------------------------------CAUCGGGAAUGUCGUGUC---------------- 12 -1,-5 -----------------------------------------------------CAUCGGGAAUGUCGUGUCa--------------- 8 -1,-5 -----------------------------------------------------CAUCGGGAAUGUCGUGUCu--------------- 5 -1,-5 -----------------------------------------------------CAUCGGGAAUGUCGUGUCC--------------- 52 -1,-4 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCuu------------- 2 -1,-4 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCG-------------- 227 -1,-3 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGa------------- 68 -1,-3 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGu------------- 320 -1,-3 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGuu------------ 51 -1,-3 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGC------------- 744 -1,-2 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGCa------------ 53 -1,-2 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGCu------------ 198 -1,-2 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGCC------------ 1014 -1,-1 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGCCa----------- 67 -1,-1 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGCCau---------- 8 -1,-1 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGCCu----------- 69 -1,-1 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGCCuu---------- 9 -1,-1 -----------------------------------------------------CAUCGGGAAUGUCGUGUCCGCCC----------- 7 -1,0 ------------------------------------------------------AUCGGGAAUGUCGUGUCC--------------- 8 0,-4 ------------------------------------------------------AUCGGGAAUGUCGUGUCCG-------------- 39 0,-3 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGu------------- 36 0,-3 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGC------------- 278 0,-2 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCa------------ 2 0,-2 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCu------------ 17 0,-2 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCC------------ 380 0,-1 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCCa----------- 14 0,-1 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCCau---------- 2 0,-1 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCCu----------- 56 0,-1 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCCuu---------- 8 0,-1 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCCC----------- 116 0,0 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCCCu---------- 16 0,0 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCCCuu--------- 32 0,0 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCCCAa--------- 2 0,1 ------------------------------------------------------AUCGGGAAUGUCGUGUCCGCCCAuu-------- 2 0,1 -------------------------------------------------------UCGGGAAUGUCGUGUCCGC------------- 3 1,-2 >hsa-mir-4286 5pM:11-27 Tumor uacuuauggcACCCCACUCCUGGUACCauagucauaaguuaggagauguuagagcugugaguaccaugacuuaagugugguggcuuaaacaug ----------ACCCCACUCCUGGUACCA----------------------------------------------------------------- 3828 0,1 ----------ACCCCACUCCUGGUACCAa---------------------------------------------------------------- 431 0,1 ----------ACCCCACUCCUGGUACCAaa--------------------------------------------------------------- 187 0,1 ----------ACCCCACUCCUGGUACCAau--------------------------------------------------------------- 34 0,1 ----------ACCCCACUCCUGGUACCAg---------------------------------------------------------------- 6 0,1 ----------ACCCCACUCCUGGUACCAU---------------------------------------------------------------- 351 0,2 ----------ACCCCACUCCUGGUACCAUu--------------------------------------------------------------- 108 0,2 ----------ACCCCACUCCUGGUACCAUuu-------------------------------------------------------------- 6 0,2 ----------ACCCCACUCCUGGUACCAUA--------------------------------------------------------------- 4 0,3 >hsa-mir-429 3pM:51-72 Tumor cgccggccgaugggcgucuuaccagacaugguuagaccuggcccucugucUAAUACUGUCUGGUAAAACCGUccauccgcugc ---------------GUCUUACCAGACAUGGUUAGA----------------------------------------------- 2 ----------------UCUUACCAGACAUGGUUAGAC---------------------------------------------- 28 ----------------UCUUACCAGACAUGGUUAGACa--------------------------------------------- 2 ----------------UCUUACCAGACAUGGUUAGACC--------------------------------------------- 40 ------------------------------------------------UCUAAUACUGUCUGGUAAAAC-------------- 7 -2,-3 ------------------------------------------------UCUAAUACUGUCUGGUAAAACC------------- 6 -2,-2 ------------------------------------------------UCUAAUACUGUCUGGUAAAACCG------------ 2 -2,-1 ------------------------------------------------UCUAAUACUGUCUGGUAAAACCGU----------- 2 -2,0 -------------------------------------------------CUAAUACUGUCUGGUAAAA--------------- 5 -1,-4 -------------------------------------------------CUAAUACUGUCUGGUAAAAa-------------- 2 -1,-4 -------------------------------------------------CUAAUACUGUCUGGUAAAAC-------------- 10 -1,-3 -------------------------------------------------CUAAUACUGUCUGGUAAAACa------------- 2 -1,-3 -------------------------------------------------CUAAUACUGUCUGGUAAAACC------------- 31 -1,-2 -------------------------------------------------CUAAUACUGUCUGGUAAAACCu------------ 4 -1,-2 -------------------------------------------------CUAAUACUGUCUGGUAAAACCG------------ 364 -1,-1 -------------------------------------------------CUAAUACUGUCUGGUAAAACCGa----------- 2 -1,-1 -------------------------------------------------CUAAUACUGUCUGGUAAAACCGU----------- 451 -1,0 --------------------------------------------------UAAUACUGUCUGGUAAAA--------------- 252 0,-4 --------------------------------------------------UAAUACUGUCUGGUAAAAa-------------- 6 0,-4 --------------------------------------------------UAAUACUGUCUGGUAAAAaa------------- 9 0,-4 --------------------------------------------------UAAUACUGUCUGGUAAAAC-------------- 162 0,-3 --------------------------------------------------UAAUACUGUCUGGUAAAACa------------- 18 0,-3 --------------------------------------------------UAAUACUGUCUGGUAAAACaa------------ 2 0,-3 --------------------------------------------------UAAUACUGUCUGGUAAAACu------------- 3 0,-3 --------------------------------------------------UAAUACUGUCUGGUAAAACC------------- 309 0,-2 --------------------------------------------------UAAUACUGUCUGGUAAAACCa------------ 12 0,-2 --------------------------------------------------UAAUACUGUCUGGUAAAACCau----------- 32 0,-2 --------------------------------------------------UAAUACUGUCUGGUAAAACCu------------ 33 0,-2 --------------------------------------------------UAAUACUGUCUGGUAAAACCuu----------- 33 0,-2 --------------------------------------------------UAAUACUGUCUGGUAAAACCG------------ 5093 0,-1 --------------------------------------------------UAAUACUGUCUGGUAAAACCGa----------- 286 0,-1 --------------------------------------------------UAAUACUGUCUGGUAAAACCGau---------- 2 0,-1 --------------------------------------------------UAAUACUGUCUGGUAAAACCGc----------- 33 0,-1 --------------------------------------------------UAAUACUGUCUGGUAAAACCGg----------- 36 0,-1 --------------------------------------------------UAAUACUGUCUGGUAAAACCGU----------- 21901 0,0 --------------------------------------------------UAAUACUGUCUGGUAAAACCGUa---------- 217 0,0 --------------------------------------------------UAAUACUGUCUGGUAAAACCGUaa--------- 5 0,0 --------------------------------------------------UAAUACUGUCUGGUAAAACCGUau--------- 6 0,0 --------------------------------------------------UAAUACUGUCUGGUAAAACCGUu---------- 223 0,0 --------------------------------------------------UAAUACUGUCUGGUAAAACCGUuu--------- 4 0,0 ---------------------------------------------------AAUACUGUCUGGUAAAACa------------- 2 1,-3 ---------------------------------------------------AAUACUGUCUGGUAAAACC------------- 2 1,-2 ---------------------------------------------------AAUACUGUCUGGUAAAACCG------------ 210 1,-1 ---------------------------------------------------AAUACUGUCUGGUAAAACCGa----------- 6 1,-1 ---------------------------------------------------AAUACUGUCUGGUAAAACCGU----------- 1023 1,0 ---------------------------------------------------AAUACUGUCUGGUAAAACCGUa---------- 9 1,0 ---------------------------------------------------AAUACUGUCUGGUAAAACCGUu---------- 36 1,0 ----------------------------------------------------AUACUGUCUGGUAAAACCG------------ 6 2,-1 ----------------------------------------------------AUACUGUCUGGUAAAACCGU----------- 51 2,0 ----------------------------------------------------AUACUGUCUGGUAAAACCGUu---------- 2 2,0 >hsa-mir-431 MA:20-40;mi:63-84 Tumor uccugcuuguccugcgaggUGUCUUGCAGGCCGUCAUGCAggccacacugacgguaacguugCAGGUCGUCUUGCAGGGCUUCUcgcaagacgacauccucaucaccaacgacg -------------------UGUCUUGCAGGCCGUCAUG---------------------------------------------------------------------------- 6 0,-2 -------------------UGUCUUGCAGGCCGUCAUGC--------------------------------------------------------------------------- 59 0,-1 -------------------UGUCUUGCAGGCCGUCAUGCc-------------------------------------------------------------------------- 2 0,-1 -------------------UGUCUUGCAGGCCGUCAUGCA-------------------------------------------------------------------------- 78 0,0 -------------------UGUCUUGCAGGCCGUCAUGCAa------------------------------------------------------------------------- 7 0,0 -------------------UGUCUUGCAGGCCGUCAUGCAGG------------------------------------------------------------------------ 2 0,2 ------------------------------------------------------------UGCAGGUCGUCUUGCAGGGCUUu------------------------------- 3 -2,-2 --------------------------------------------------------------CAGGUCGUCUUGCAGGGCUUCU------------------------------ 2 0,0 >hsa-mir-432 MA:14-36;mi:62-82 Tumor ugacuccuccaggUCUUGGAGUAGGUCAUUGGGUGGauccucuauuuccuuacgugggccaCUGGAUGGCUCCUCCAUGUCUuggaguagauca -------------UCUUGGAGUAGGUCAUUGG-------------------------------------------------------------- 4 0,-4 -------------UCUUGGAGUAGGUCAUUGGa------------------------------------------------------------- 2 0,-4 -------------UCUUGGAGUAGGUCAUUGGG------------------------------------------------------------- 3 0,-3 -------------UCUUGGAGUAGGUCAUUGGGa------------------------------------------------------------ 2 0,-3 -------------UCUUGGAGUAGGUCAUUGGGU------------------------------------------------------------ 34 0,-2 -------------UCUUGGAGUAGGUCAUUGGGUa----------------------------------------------------------- 2 0,-2 -------------UCUUGGAGUAGGUCAUUGGGUu----------------------------------------------------------- 2 0,-2 -------------UCUUGGAGUAGGUCAUUGGGUG----------------------------------------------------------- 13 0,-1 -------------UCUUGGAGUAGGUCAUUGGGUGa---------------------------------------------------------- 19 0,-1 -------------UCUUGGAGUAGGUCAUUGGGUGu---------------------------------------------------------- 54 0,-1 -------------UCUUGGAGUAGGUCAUUGGGUGG---------------------------------------------------------- 9 0,0 >hsa-mir-4326 5pM:11-30 Tumor gcugcucugcUGUUCCUCUGUCUCCCAGACucuggguggauggagcaggucgggggcca ----------UGUUCCUCUGUCUCCCAG------------------------------- 2 0,-2 ----------UGUUCCUCUGUCUCCCAGAC----------------------------- 9 0,0 ----------UGUUCCUCUGUCUCCCAGACa---------------------------- 2 0,0 ----------UGUUCCUCUGUCUCCCAGACU---------------------------- 44 0,1 ----------UGUUCCUCUGUCUCCCAGACUC--------------------------- 2 0,2 ----------UGUUCCUCUGUCUCCCAGACUCU-------------------------- 56 0,3 ----------UGUUCCUCUGUCUCCCAGACUCUG------------------------- 24 0,4 ----------UGUUCCUCUGUCUCCCAGACUCUGa------------------------ 4 0,4 ----------UGUUCCUCUGUCUCCCAGACUCUGu------------------------ 6 0,4 -----------GUUCCUCUGUCUCCCAGACU---------------------------- 2 1,1 >hsa-mir-433 3pM:64-85 Tumor ccggggagaaguacggugagccugucauuauucagagaggcuagauccucuguguugagaaggAUCAUGAUGGGCUCCUCGGUGUucuccagg ---------------------------------------------------------------AUCAUGAUGGGCUCCUCGGU---------- 2 0,-2 ---------------------------------------------------------------AUCAUGAUGGGCUCCUCGGUu--------- 2 0,-2 ---------------------------------------------------------------AUCAUGAUGGGCUCCUCGGUGU-------- 110 0,0 ---------------------------------------------------------------AUCAUGAUGGGCUCCUCGGUGUau------ 4 0,0 ---------------------------------------------------------------AUCAUGAUGGGCUCCUCGGUGUUu------ 2 0,1 ----------------------------------------------------------------UCAUGAUGGGCUCCUCGGUGU-------- 2 1,0 >hsa-mir-4417 5pM:12-29 Tumor gaaaacaaccaGGUGGGCUUCCCGGAGGGcggaacacccagccccagcauccagggcucaccuaccacguuug -----------GGUGGGCUUCCCGGAGGG-------------------------------------------- 19 0,0 >hsa-mir-4423 5p:13-34;3p:49-69 Tumor aucauguacugcAGUUGCCUUUUUGUUCCCAUGCuguuuaagccuagcAUAGGCACCAAAAAGCAACAAcaguaugugaa ------------AGUUGCCUUUUUGUUCCCAUGC---------------------------------------------- 9 0,0 -------------GUUGCCUUUUUGUUCCCAUGCU--------------------------------------------- 2 1,1 ------------------------------------------------AUAGGCACCAAAAAGCAACA------------ 2 0,-1 >hsa-mir-4424 5pM:15-36 Tumor cuuacaucacacacAGAGUUAACUCAAAAUGGACUAauuuuuccacuaguuaguccauuucaaguuaacucugugugugauguagu --------------AGAGUUAACUCAAAAUGGACU--------------------------------------------------- 2 0,-1 >hsa-mir-4429 5pM:7-26 Tumor agggagAAAAGCUGGGCUGAGAGGCGacuggugucuaauuuguuugucucuccaacucagacugccuggccca ------AAAAGCUGGGCUGAGAGG------------------------------------------------- 133 0,-2 >hsa-mir-4430 5pM:4-21 Tumor gugAGGCUGGAGUGAGCGGAGaucguaccacugcacuccaaccugguga ---AGGCUGGAGUGAGCGGAG---------------------------- 2 0,0 >hsa-mir-4446 5p:8-29;3p:43-64 Tumor cugguccAUUUCCCUGCCAUUCCCUUGGCuucaauuuacuccCAGGGCUGGCAGUGACAUGGGUcaa ------------------------------------------CAGGGCUGGCAGUGACAUGG----- 11 0,-2 ------------------------------------------CAGGGCUGGCAGUGACAUGGG---- 6 0,-1 ------------------------------------------CAGGGCUGGCAGUGACAUGGGU--- 32 0,0 >hsa-mir-4448 3pM:61-80 Tumor aggagugaccaaaagacaagagugcgagccuucuauuaugcccagacagggccaccagagGGCUCCUUGGUCUAGGGGUAaugcca --------------------------------------------------------------CUCCUUGGUCUAGGGGUA------ 2 2,0 >hsa-mir-4449 3pM:39-60 Tumor agcagcccucggcggcccggggggcgggcggcggugccCGUCCCGGGGCUGCGCGAGGCAcaggcg ------CCUCGGCGGCCCGGGGGGCGGG-------------------------------------- 2 ----------------------------------------UCCCGGGGCUGCGCGAGGC------- 2 2,-1 >hsa-mir-4454 5pM:3-22 Tumor ccGGAUCCGAGUCACGGCACCAaauuucaugcguguccgugugaagagaccacca -CGGAUCCGAGUCACGGCACCA--------------------------------- 73 -1,0 --GGAUCCGAGUCACGGCACCA--------------------------------- 6 0,0 ---GAUCCGAGUCACGGCACCA--------------------------------- 37 1,0 ----AUCCGAGUCACGGCACCA--------------------------------- 588 2,0 ----AUCCGAGUCACGGCACCAuu------------------------------- 3 2,0 ----AUCCGAGUCACGGCACCAA-------------------------------- 4 2,1 ----AUCCGAGUCACGGCACCAAA------------------------------- 3 2,2 ----AUCCGAGUCACGGCACCAAAa------------------------------ 2 2,2 >hsa-mir-4466 5pM:5-22 Tumor acgcGGGUGCGGGCCGGCGGGGuagaagccacccggcccggcccggcccggcga ----GGGUGCGGGCCGGCGGGG-------------------------------- 2 0,0 >hsa-mir-4473 3pM:57-78 Tumor aaggaacaggggacacuuguaauggagaacacuaagcuauggacugcuauggacugCUAGUGCUCUCCGUUACAAGUAuccccuguuaccu --------------------------------------------------------CUAGUGCUCUCCGUUACAAGU-------------- 2 0,-1 ---------------------------------------------------------UAGUGCUCUCCGUUACAAGUAU------------ 3 1,1 >hsa-mir-4477b 3pM:50-71 Tumor accuccucccgugaaucacaaauguccuuaauagcaauccuuaaaugccAUUAAGGACAUUUGUGAUUGAUgggaggagga -------------------------------------------------AUUAAGGACAUUUGUGAUUGAU---------- 2 0,0 >hsa-mir-4484 3pM:64-83 Tumor ggguuuccucugccuuuuuuuccaaugaaaauaacgaaaccuguuauuucccauugagggggaAAAAGGCGGGAGAAGCCCCA --------------------------------------------------------------AAAAAGGCGGGAGAAGCCCC- 4 -1,-1 --------------------------------------------------------------AAAAAGGCGGGAGAAGCCCCA 2 -1,0 ---------------------------------------------------------------AAAAGGCGGGAGAAGCCCa- 2 0,-2 ---------------------------------------------------------------AAAAGGCGGGAGAAGCCCC- 20 0,-1 ----------------------------------------------------------------AAAGGCGGGAGAAGCCCCA 2 1,0 >hsa-mir-4488 5pM:4-21 Tumor gguAGGGGGCGGGCUCCGGCGcugggaccccacuaggguggcgccuuggccccgccccgccc ---AGGGGGCGGGCUCCGGCG----------------------------------------- 567 0,0 ---AGGGGGCGGGCUCCGGCGg---------------------------------------- 109 0,0 >hsa-mir-449a 5pM:16-37 Tumor cugugugugaugagcUGGCAGUGUAUUGUUAGCUGGUugaauaugugaauggcaucggcuaacaugcaacugcugucuuauugcauauaca ---------------UGGCAGUGUAUUGUUAGCU--------------------------------------------------------- 17 0,-3 ---------------UGGCAGUGUAUUGUUAGCUG-------------------------------------------------------- 17 0,-2 ---------------UGGCAGUGUAUUGUUAGCUGuu------------------------------------------------------ 4 0,-2 ---------------UGGCAGUGUAUUGUUAGCUGG------------------------------------------------------- 115 0,-1 ---------------UGGCAGUGUAUUGUUAGCUGGaa----------------------------------------------------- 2 0,-1 ---------------UGGCAGUGUAUUGUUAGCUGGU------------------------------------------------------ 1639 0,0 ---------------UGGCAGUGUAUUGUUAGCUGGUa----------------------------------------------------- 87 0,0 ---------------UGGCAGUGUAUUGUUAGCUGGUaa---------------------------------------------------- 26 0,0 ---------------UGGCAGUGUAUUGUUAGCUGGUau---------------------------------------------------- 37 0,0 ---------------UGGCAGUGUAUUGUUAGCUGGUU----------------------------------------------------- 70 0,1 ---------------UGGCAGUGUAUUGUUAGCUGGUUu---------------------------------------------------- 5 0,1 ----------------GGCAGUGUAUUGUUAGCUGG------------------------------------------------------- 4 1,-1 ----------------GGCAGUGUAUUGUUAGCUGGU------------------------------------------------------ 45 1,0 ----------------GGCAGUGUAUUGUUAGCUGGUa----------------------------------------------------- 3 1,0 ----------------GGCAGUGUAUUGUUAGCUGGUau---------------------------------------------------- 3 1,0 -------------------------------------------------------CGGCUAACAUGCAACUGCUGUC-------------- 8 >hsa-mir-449b MA:16-37;mi:55-76 Tumor ugaccugaaucagguAGGCAGUGUAUUGUUAGCUGGCugcuugggucaagucagCAGCCACAACUACCCUGCCACUugcuucuggauaaauucuucu ---------------AGGCAGUGUAUUGUUAGCUGG------------------------------------------------------------- 11 0,-1 ---------------AGGCAGUGUAUUGUUAGCUGGC------------------------------------------------------------ 19 0,0 ---------------AGGCAGUGUAUUGUUAGCUGGCU----------------------------------------------------------- 39 0,1 ---------------AGGCAGUGUAUUGUUAGCUGGCUG---------------------------------------------------------- 21 0,2 ---------------AGGCAGUGUAUUGUUAGCUGGCUGu--------------------------------------------------------- 12 0,2 ---------------AGGCAGUGUAUUGUUAGCUGGCUGC--------------------------------------------------------- 10 0,3 ----------------GGCAGUGUAUUGUUAGCUGG------------------------------------------------------------- 4 1,-1 ------------------------------------------------------CAGCCACAACUACCCUGCCACU--------------------- 2 0,0 >hsa-mir-449c MA:17-41;mi:57-79 Tumor gcugggaugugucaggUAGGCAGUGUAUUGCUAGCGGCUGUuaaugauuuuaacagUUGCUAGUUGCACUCCUCUCUGUugcauucagaagc ----------------UAGGCAGUGUAUUGCUAGCGG------------------------------------------------------- 2 0,-4 ----------------UAGGCAGUGUAUUGCUAGCGGCU----------------------------------------------------- 3 0,-2 ----------------UAGGCAGUGUAUUGCUAGCGGCUGg--------------------------------------------------- 2 0,-1 ----------------UAGGCAGUGUAUUGCUAGCGGCUGU--------------------------------------------------- 4 0,0 -----------------AGGCAGUGUAUUGCUAGCG-------------------------------------------------------- 2 1,-5 -----------------AGGCAGUGUAUUGCUAGCGG------------------------------------------------------- 4 1,-4 -----------------AGGCAGUGUAUUGCUAGCGGCUGg--------------------------------------------------- 4 1,-1 -----------------AGGCAGUGUAUUGCUAGCGGCUGU--------------------------------------------------- 4 1,0 >hsa-mir-4504 3pM:55-76 Tumor cuaagauaauguccuccagguucaucucuguugucauuuguggcauggaccauuUGUGACAAUAGAGAUGAACAUGgaggauauuaucuuaa ------------------------------------------------------UGUGACAAUAGAGAUGAACAUG---------------- 2 0,0 >hsa-mir-4508 5pM:9-25 Tumor aggacccaGCGGGGCUGGGCGCGCGgagcagcgcugggugcagcgccugcgccggcagcugcaagggccg -------AGCGGGGCUGGGCGCGCG--------------------------------------------- 5 -1,0 >hsa-mir-450a-1 5pM:18-39 Tumor aaacgauacuaaacuguUUUUGCGAUGUGUUCCUAAUAUgcacuauaaauauauugggaacauuuugcauguauaguuuuguaucaauaua -----------------UUUUGCGAUGUGUUCCUA-------------------------------------------------------- 9 0,-4 -----------------UUUUGCGAUGUGUUCCUAu------------------------------------------------------- 4 0,-4 -----------------UUUUGCGAUGUGUUCCUAA------------------------------------------------------- 55 0,-3 -----------------UUUUGCGAUGUGUUCCUAAa------------------------------------------------------ 8 0,-3 -----------------UUUUGCGAUGUGUUCCUAAaa----------------------------------------------------- 2 0,-3 -----------------UUUUGCGAUGUGUUCCUAAU------------------------------------------------------ 877 0,-2 -----------------UUUUGCGAUGUGUUCCUAAUu----------------------------------------------------- 7 0,-2 -----------------UUUUGCGAUGUGUUCCUAAUA----------------------------------------------------- 583 0,-1 -----------------UUUUGCGAUGUGUUCCUAAUAa---------------------------------------------------- 67 0,-1 -----------------UUUUGCGAUGUGUUCCUAAUAaa--------------------------------------------------- 5 0,-1 -----------------UUUUGCGAUGUGUUCCUAAUAU---------------------------------------------------- 1243 0,0 -----------------UUUUGCGAUGUGUUCCUAAUAUa--------------------------------------------------- 39 0,0 -----------------UUUUGCGAUGUGUUCCUAAUAUu--------------------------------------------------- 7 0,0 -----------------UUUUGCGAUGUGUUCCUAAUAUG--------------------------------------------------- 26 0,1 ------------------UUUGCGAUGUGUUCCUAAUA----------------------------------------------------- 2 1,-1 ------------------UUUGCGAUGUGUUCCUAAUAU---------------------------------------------------- 9 1,0 ----------------------------------------------------AUUGGGAACAUUUUGCAUGUA------------------ 4 ----------------------------------------------------AUUGGGAACAUUUUGCAUGUAU----------------- 134 -----------------------------------------------------UUGGGAACAUUUUGCAUGUAU----------------- 9 >hsa-mir-450a-2 5pM:23-44 Tumor ccaaagaaagaugcuaaacuauUUUUGCGAUGUGUUCCUAAUAUguaauauaaauguauuggggacauuuugcauucauaguuuuguaucaauaauaugg ----------------------UUUUGCGAUGUGUUCCUA------------------------------------------------------------ 9 0,-4 ----------------------UUUUGCGAUGUGUUCCUAu----------------------------------------------------------- 4 0,-4 ----------------------UUUUGCGAUGUGUUCCUAA----------------------------------------------------------- 55 0,-3 ----------------------UUUUGCGAUGUGUUCCUAAa---------------------------------------------------------- 8 0,-3 ----------------------UUUUGCGAUGUGUUCCUAAaa--------------------------------------------------------- 2 0,-3 ----------------------UUUUGCGAUGUGUUCCUAAU---------------------------------------------------------- 877 0,-2 ----------------------UUUUGCGAUGUGUUCCUAAUu--------------------------------------------------------- 7 0,-2 ----------------------UUUUGCGAUGUGUUCCUAAUA--------------------------------------------------------- 583 0,-1 ----------------------UUUUGCGAUGUGUUCCUAAUAa-------------------------------------------------------- 67 0,-1 ----------------------UUUUGCGAUGUGUUCCUAAUAaa------------------------------------------------------- 5 0,-1 ----------------------UUUUGCGAUGUGUUCCUAAUAU-------------------------------------------------------- 1243 0,0 ----------------------UUUUGCGAUGUGUUCCUAAUAUa------------------------------------------------------- 39 0,0 ----------------------UUUUGCGAUGUGUUCCUAAUAUu------------------------------------------------------- 7 0,0 ----------------------UUUUGCGAUGUGUUCCUAAUAUG------------------------------------------------------- 26 0,1 ----------------------UUUUGCGAUGUGUUCCUAAUAUGU------------------------------------------------------ 2 0,2 -----------------------UUUGCGAUGUGUUCCUAAUA--------------------------------------------------------- 2 1,-1 -----------------------UUUGCGAUGUGUUCCUAAUAU-------------------------------------------------------- 9 1,0 ---------------------------------------------------------AUUGGGGACAUUUUGCAUUCA---------------------- 7 ---------------------------------------------------------AUUGGGGACAUUUUGCAUUCAU--------------------- 13 ----------------------------------------------------------UUGGGGACAUUUUGCAUUC----------------------- 2 ----------------------------------------------------------UUGGGGACAUUUUGCAUUCA---------------------- 2 ----------------------------------------------------------UUGGGGACAUUUUGCAUUCAU--------------------- 12 >hsa-mir-450b 5p:11-32;3p:48-69 Tumor gcagaauuauUUUUGCAAUAUGUUCCUGAAUAuguaauauaaguguaUUGGGAUCAUUUUGCAUCCAUAguuuuguau ----------UUUUGCAAUAUGUUCCUG-------------------------------------------------- 4 0,-4 ----------UUUUGCAAUAUGUUCCUGAA------------------------------------------------ 11 0,-2 ----------UUUUGCAAUAUGUUCCUGAAU----------------------------------------------- 831 0,-1 ----------UUUUGCAAUAUGUUCCUGAAUu---------------------------------------------- 3 0,-1 ----------UUUUGCAAUAUGUUCCUGAAUA---------------------------------------------- 341 0,0 ----------UUUUGCAAUAUGUUCCUGAAUAa--------------------------------------------- 16 0,0 ----------UUUUGCAAUAUGUUCCUGAAUAU--------------------------------------------- 39 0,1 ----------UUUUGCAAUAUGUUCCUGAAUAUG-------------------------------------------- 2 0,2 -----------UUUGCAAUAUGUUCCUGAAU----------------------------------------------- 7 1,-1 ----------------------------------------------AUUGGGAUCAUUUUGCAUCCAU---------- 4 -1,-1 >hsa-mir-451 5pM:17-38 Tumor cuugggaauggcaaggAAACCGUUACCAUUACUGAGUUuaguaaugguaaugguucucuugcuauacccaga ----------------AAACCGUUACCAUUACUG-------------------------------------- 1679 0,-4 ----------------AAACCGUUACCAUUACUGA------------------------------------- 936 0,-3 ----------------AAACCGUUACCAUUACUGAau----------------------------------- 51 0,-3 ----------------AAACCGUUACCAUUACUGAu------------------------------------ 16 0,-3 ----------------AAACCGUUACCAUUACUGAuu----------------------------------- 129 0,-3 ----------------AAACCGUUACCAUUACUGAG------------------------------------ 6737 0,-2 ----------------AAACCGUUACCAUUACUGAGa----------------------------------- 72 0,-2 ----------------AAACCGUUACCAUUACUGAGau---------------------------------- 51 0,-2 ----------------AAACCGUUACCAUUACUGAGc----------------------------------- 146 0,-2 ----------------AAACCGUUACCAUUACUGAGg----------------------------------- 239 0,-2 ----------------AAACCGUUACCAUUACUGAGU----------------------------------- 52827 0,-1 ----------------AAACCGUUACCAUUACUGAGUa---------------------------------- 48 0,-1 ----------------AAACCGUUACCAUUACUGAGUau--------------------------------- 12 0,-1 ----------------AAACCGUUACCAUUACUGAGUc---------------------------------- 83 0,-1 ----------------AAACCGUUACCAUUACUGAGUg---------------------------------- 25 0,-1 ----------------AAACCGUUACCAUUACUGAGUU---------------------------------- 66642 0,0 ----------------AAACCGUUACCAUUACUGAGUUa--------------------------------- 90 0,0 ----------------AAACCGUUACCAUUACUGAGUUc--------------------------------- 45 0,0 ----------------AAACCGUUACCAUUACUGAGUUg--------------------------------- 4 0,0 ----------------AAACCGUUACCAUUACUGAGUUU--------------------------------- 25108 0,1 ----------------AAACCGUUACCAUUACUGAGUUUu-------------------------------- 2 0,1 ----------------AAACCGUUACCAUUACUGAGUUUA-------------------------------- 1047 0,2 ----------------AAACCGUUACCAUUACUGAGUUUAa------------------------------- 3 0,2 ----------------AAACCGUUACCAUUACUGAGUUUAc------------------------------- 2 0,2 ----------------AAACCGUUACCAUUACUGAGUUUAu------------------------------- 14 0,2 ----------------AAACCGUUACCAUUACUGAGUUUAG------------------------------- 1705 0,3 -----------------AACCGUUACCAUUACUGA------------------------------------- 12 1,-3 -----------------AACCGUUACCAUUACUGAuu----------------------------------- 2 1,-3 -----------------AACCGUUACCAUUACUGAG------------------------------------ 125 1,-2 -----------------AACCGUUACCAUUACUGAGc----------------------------------- 2 1,-2 -----------------AACCGUUACCAUUACUGAGg----------------------------------- 2 1,-2 -----------------AACCGUUACCAUUACUGAGU----------------------------------- 1293 1,-1 -----------------AACCGUUACCAUUACUGAGUU---------------------------------- 1655 1,0 -----------------AACCGUUACCAUUACUGAGUUU--------------------------------- 662 1,1 -----------------AACCGUUACCAUUACUGAGUUUA-------------------------------- 24 1,2 -----------------AACCGUUACCAUUACUGAGUUUAG------------------------------- 23 1,3 -----------------AACCGUUACCAUUACUGAGUUUAGU------------------------------ 17 1,4 >hsa-mir-4510 5pM:8-29 Tumor guguaugUGAGGGAGUAGGAUGUAUGGUUguuagauagacaacuacaaucuuuucucacaacagacag -------UGAGGGAGUAGGAUGUAU------------------------------------------- 14 0,-4 >hsa-mir-4519 5pM:6-23 Tumor aaccuCAGCAGUGCGCAGGGCUGcacugucuccgucugcggccugcaguaagcgggua ---CUCAGCAGUGCGCAGGGCUG----------------------------------- 2 -2,0 -----CAGCAGUGCGCAGGGCUG----------------------------------- 2 0,0 >hsa-mir-452 MA:14-35;mi:58-79 Tumor gcuaagcacuuacAACUGUUUGCAGAGGAAACUGAgacuuuguaacuaugucucaguCUCAUCUGCAAAGAAGUAAGUGcuuugc ------------CAACUGUUUGCAGAGGAAACUGA-------------------------------------------------- 9 -1,0 ------------CAACUGUUUGCAGAGGAAACUGAG------------------------------------------------- 2 -1,1 -------------AACUGUUUGCAGAGGAAA------------------------------------------------------ 47 0,-4 -------------AACUGUUUGCAGAGGAAAa----------------------------------------------------- 3 0,-4 -------------AACUGUUUGCAGAGGAAAC----------------------------------------------------- 27 0,-3 -------------AACUGUUUGCAGAGGAAACU---------------------------------------------------- 60 0,-2 -------------AACUGUUUGCAGAGGAAACUaa-------------------------------------------------- 4 0,-2 -------------AACUGUUUGCAGAGGAAACUG--------------------------------------------------- 493 0,-1 -------------AACUGUUUGCAGAGGAAACUGc-------------------------------------------------- 9 0,-1 -------------AACUGUUUGCAGAGGAAACUGu-------------------------------------------------- 112 0,-1 -------------AACUGUUUGCAGAGGAAACUGA-------------------------------------------------- 3386 0,0 -------------AACUGUUUGCAGAGGAAACUGAa------------------------------------------------- 101 0,0 -------------AACUGUUUGCAGAGGAAACUGAaa------------------------------------------------ 10 0,0 -------------AACUGUUUGCAGAGGAAACUGAau------------------------------------------------ 2 0,0 -------------AACUGUUUGCAGAGGAAACUGAc------------------------------------------------- 5 0,0 -------------AACUGUUUGCAGAGGAAACUGAu------------------------------------------------- 22 0,0 -------------AACUGUUUGCAGAGGAAACUGAG------------------------------------------------- 1692 0,1 -------------AACUGUUUGCAGAGGAAACUGAGu------------------------------------------------ 139 0,1 -------------AACUGUUUGCAGAGGAAACUGAGA------------------------------------------------ 1543 0,2 -------------AACUGUUUGCAGAGGAAACUGAGAa----------------------------------------------- 15 0,2 -------------AACUGUUUGCAGAGGAAACUGAGAg----------------------------------------------- 2 0,2 -------------AACUGUUUGCAGAGGAAACUGAGAu----------------------------------------------- 10 0,2 --------------ACUGUUUGCAGAGGAAACUG--------------------------------------------------- 2 1,-1 --------------ACUGUUUGCAGAGGAAACUGu-------------------------------------------------- 2 1,-1 --------------ACUGUUUGCAGAGGAAACUGA-------------------------------------------------- 59 1,0 --------------ACUGUUUGCAGAGGAAACUGAa------------------------------------------------- 2 1,0 --------------ACUGUUUGCAGAGGAAACUGAG------------------------------------------------- 33 1,1 --------------ACUGUUUGCAGAGGAAACUGAGu------------------------------------------------ 2 1,1 --------------ACUGUUUGCAGAGGAAACUGAGA------------------------------------------------ 56 1,2 ---------------CUGUUUGCAGAGGAAACUG--------------------------------------------------- 2 2,-1 ---------------CUGUUUGCAGAGGAAACUGA-------------------------------------------------- 11 2,0 ---------------CUGUUUGCAGAGGAAACUGAG------------------------------------------------- 19 2,1 ---------------CUGUUUGCAGAGGAAACUGAGA------------------------------------------------ 146 2,2 ---------------CUGUUUGCAGAGGAAACUGAGAa----------------------------------------------- 4 2,2 ---------------CUGUUUGCAGAGGAAACUGAGAaa---------------------------------------------- 2 2,2 ---------------CUGUUUGCAGAGGAAACUGAGAC----------------------------------------------- 2 2,3 ---------------------------------------------------CUCAGUCUCAUCUGCAAAGA-------------- 54 -6,-8 ---------------------------------------------------CUCAGUCUCAUCUGCAAAGAA------------- 20 -6,-7 ---------------------------------------------------CUCAGUCUCAUCUGCAAAGAAa------------ 8 -6,-7 ---------------------------------------------------CUCAGUCUCAUCUGCAAAGAAG------------ 102 -6,-6 ---------------------------------------------------CUCAGUCUCAUCUGCAAAGAAGU----------- 11 -6,-5 ---------------------------------------------------CUCAGUCUCAUCUGCAAAGAAGUu---------- 2 -6,-5 ----------------------------------------------------UCAGUCUCAUCUGCAAAG--------------- 7 -5,-9 ----------------------------------------------------UCAGUCUCAUCUGCAAAGA-------------- 25 -5,-8 ----------------------------------------------------UCAGUCUCAUCUGCAAAGAA------------- 45 -5,-7 ----------------------------------------------------UCAGUCUCAUCUGCAAAGAAa------------ 20 -5,-7 ----------------------------------------------------UCAGUCUCAUCUGCAAAGAAaa----------- 2 -5,-7 ----------------------------------------------------UCAGUCUCAUCUGCAAAGAAG------------ 422 -5,-6 ----------------------------------------------------UCAGUCUCAUCUGCAAAGAAGa----------- 2 -5,-6 ----------------------------------------------------UCAGUCUCAUCUGCAAAGAAGU----------- 1578 -5,-5 ----------------------------------------------------UCAGUCUCAUCUGCAAAGAAGUu---------- 8 -5,-5 ----------------------------------------------------UCAGUCUCAUCUGCAAAGAAGUA---------- 11 -5,-4 ----------------------------------------------------UCAGUCUCAUCUGCAAAGAAGUAA--------- 2 -5,-3 >hsa-mir-4521 5pM:4-25 Tumor ucgGCUAAGGAAGUCCUGUGCUCAGuuuuguagcaucaaaacuaggauuucucuuguuac ---GCUAAGGAAGUCCUGUGCUCAG----------------------------------- 3 0,0 ---GCUAAGGAAGUCCUGUGCUCAGU---------------------------------- 77 0,1 ---GCUAAGGAAGUCCUGUGCUCAGUU--------------------------------- 9 0,2 ---GCUAAGGAAGUCCUGUGCUCAGUUU-------------------------------- 71 0,3 >hsa-mir-4524 MA:6-27;mi:42-63 Tumor gaacgAUAGCAGCAUGAACCUGUCUCAcugcagaauuauuuUGAGACAGGCUUAUGCUGCUAUccuuca -------AGCAGCAUGAACCUGUCUCACU---------------------------------------- 2 2,2 -----------------------------------------UGAGACAGGCUUAUGCUGCUAU------ 6 0,0 >hsa-mir-4526 3pM:54-75 Tumor ugcggugacaucagggcccagucccugcugucaugccccaggugacgugcuggGCUGACAGCAGGGCUGGCCGCUaacgucacuguc -----------------------------------------------------GCUGACAGCAGGGCUGGCCGCU------------ 14 0,0 -----------------------------------------------------GCUGACAGCAGGGCUGGCCGCUu----------- 4 0,0 >hsa-mir-4532 5pM:6-22 Tumor acagaCCCCGGGGAGCCCGGCGgugaagcuccugguauccugggugucuga -----CCCCGGGGAGCCCGGCGG---------------------------- 467 0,1 -----CCCCGGGGAGCCCGGCGGg--------------------------- 224 0,1 >hsa-mir-454 mi:24-45;MA:64-86 Tumor ucuguuuaucaccagauccuagaACCCUAUCAAUAUUGUCUCUGCuguguaaauaguucugagUAGUGCAAUAUUGCUUAUAGGGUuuugguguuuggaaagaacaaugggcagg -----------------------ACCCUAUCAAUAUUGUCUCU------------------------------------------------------------------------ 2 0,-2 -----------------------ACCCUAUCAAUAUUGUCUCUG----------------------------------------------------------------------- 17 0,-1 -----------------------ACCCUAUCAAUAUUGUCUCUGC---------------------------------------------------------------------- 24 0,0 -----------------------ACCCUAUCAAUAUUGUCUCUGCUG-------------------------------------------------------------------- 2 0,2 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUA--------------------------------- 2 0,-4 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAG-------------------------------- 19 0,-3 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGG------------------------------- 194 0,-2 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGGa------------------------------ 62 0,-2 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGGaa----------------------------- 5 0,-2 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGGau----------------------------- 2 0,-2 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGGG------------------------------ 287 0,-1 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGGGa----------------------------- 276 0,-1 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGGGaa---------------------------- 9 0,-1 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGGGU----------------------------- 1458 0,0 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGGGUa---------------------------- 21 0,0 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGGGUau--------------------------- 2 0,0 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGGGUU---------------------------- 487 0,1 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGGGUUc--------------------------- 2 0,1 ---------------------------------------------------------------UAGUGCAAUAUUGCUUAUAGGGUUU--------------------------- 251 0,2 ----------------------------------------------------------------AGUGCAAUAUUGCUUAUAGG------------------------------- 2 1,-2 ----------------------------------------------------------------AGUGCAAUAUUGCUUAUAGGa------------------------------ 2 1,-2 ----------------------------------------------------------------AGUGCAAUAUUGCUUAUAGGG------------------------------ 7 1,-1 ----------------------------------------------------------------AGUGCAAUAUUGCUUAUAGGGa----------------------------- 12 1,-1 ----------------------------------------------------------------AGUGCAAUAUUGCUUAUAGGGU----------------------------- 54 1,0 ----------------------------------------------------------------AGUGCAAUAUUGCUUAUAGGGUU---------------------------- 20 1,1 ----------------------------------------------------------------AGUGCAAUAUUGCUUAUAGGGUUU--------------------------- 10 1,2 >hsa-mir-455 5p:16-37;3p:54-74 Tumor ucccuggcgugagggUAUGUGCCUUUGGACUACAUCGuggaagccagcaccauGCAGUCCAUGGGCAUAUACACuugccucaaggccuaugucauc --------------GUAUGUGCCUUUGGACUA---------------------------------------------------------------- 6 -1,-5 --------------GUAUGUGCCUUUGGACUAa--------------------------------------------------------------- 2 -1,-5 --------------GUAUGUGCCUUUGGACUAu--------------------------------------------------------------- 2 -1,-5 --------------GUAUGUGCCUUUGGACUAC--------------------------------------------------------------- 59 -1,-4 --------------GUAUGUGCCUUUGGACUACA-------------------------------------------------------------- 168 -1,-3 --------------GUAUGUGCCUUUGGACUACAa------------------------------------------------------------- 2 -1,-3 --------------GUAUGUGCCUUUGGACUACAU------------------------------------------------------------- 340 -1,-2 --------------GUAUGUGCCUUUGGACUACAUa------------------------------------------------------------ 26 -1,-2 --------------GUAUGUGCCUUUGGACUACAUu------------------------------------------------------------ 7 -1,-2 --------------GUAUGUGCCUUUGGACUACAUC------------------------------------------------------------ 16 -1,-1 --------------GUAUGUGCCUUUGGACUACAUCG----------------------------------------------------------- 47 -1,0 --------------GUAUGUGCCUUUGGACUACAUCGU---------------------------------------------------------- 18 -1,1 --------------GUAUGUGCCUUUGGACUACAUCGUG--------------------------------------------------------- 3 -1,2 ---------------UAUGUGCCUUUGGACUAC--------------------------------------------------------------- 6 0,-4 ---------------UAUGUGCCUUUGGACUACA-------------------------------------------------------------- 42 0,-3 ---------------UAUGUGCCUUUGGACUACAU------------------------------------------------------------- 72 0,-2 ---------------UAUGUGCCUUUGGACUACAUa------------------------------------------------------------ 2 0,-2 ---------------UAUGUGCCUUUGGACUACAUC------------------------------------------------------------ 44 0,-1 ---------------UAUGUGCCUUUGGACUACAUCa----------------------------------------------------------- 25 0,-1 ---------------UAUGUGCCUUUGGACUACAUCaa---------------------------------------------------------- 2 0,-1 ---------------UAUGUGCCUUUGGACUACAUCu----------------------------------------------------------- 4 0,-1 ---------------UAUGUGCCUUUGGACUACAUCG----------------------------------------------------------- 1914 0,0 ---------------UAUGUGCCUUUGGACUACAUCGa---------------------------------------------------------- 27 0,0 ---------------UAUGUGCCUUUGGACUACAUCGU---------------------------------------------------------- 225 0,1 ---------------UAUGUGCCUUUGGACUACAUCGUG--------------------------------------------------------- 5 0,2 ----------------AUGUGCCUUUGGACUACAU------------------------------------------------------------- 6 1,-2 ----------------AUGUGCCUUUGGACUACAUCG----------------------------------------------------------- 73 1,0 ----------------AUGUGCCUUUGGACUACAUCGU---------------------------------------------------------- 33 1,1 -----------------UGUGCCUUUGGACUACAUCG----------------------------------------------------------- 4 2,0 -----------------UGUGCCUUUGGACUACAUCGU---------------------------------------------------------- 55 2,1 -----------------UGUGCCUUUGGACUACAUCGUG--------------------------------------------------------- 127 2,2 -----------------UGUGCCUUUGGACUACAUCGUGa-------------------------------------------------------- 29 2,2 -----------------UGUGCCUUUGGACUACAUCGUGu-------------------------------------------------------- 11 2,2 ---------------------------------------------------AUGCAGUCCAUGGGCAUA--------------------------- 14 -2,-5 ---------------------------------------------------AUGCAGUCCAUGGGCAUAU-------------------------- 105 -2,-4 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUu------------------------- 16 -2,-4 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUA------------------------- 57 -2,-3 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUAa------------------------ 18 -2,-3 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUAaa----------------------- 2 -2,-3 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUAu------------------------ 6 -2,-3 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUAC------------------------ 354 -2,-2 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUACc----------------------- 2 -2,-2 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUACg----------------------- 3 -2,-2 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUACA----------------------- 653 -2,-1 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUACAa---------------------- 9 -2,-1 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUACAC---------------------- 472 -2,0 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUACACc--------------------- 2 -2,0 ---------------------------------------------------AUGCAGUCCAUGGGCAUAUACACU--------------------- 14 -2,1 ----------------------------------------------------UGCAGUCCAUGGGCAUAU-------------------------- 14 -1,-4 ----------------------------------------------------UGCAGUCCAUGGGCAUAUu------------------------- 8 -1,-4 ----------------------------------------------------UGCAGUCCAUGGGCAUAUA------------------------- 22 -1,-3 ----------------------------------------------------UGCAGUCCAUGGGCAUAUAa------------------------ 4 -1,-3 ----------------------------------------------------UGCAGUCCAUGGGCAUAUAC------------------------ 98 -1,-2 ----------------------------------------------------UGCAGUCCAUGGGCAUAUACA----------------------- 341 -1,-1 ----------------------------------------------------UGCAGUCCAUGGGCAUAUACAa---------------------- 6 -1,-1 ----------------------------------------------------UGCAGUCCAUGGGCAUAUACAC---------------------- 275 -1,0 ----------------------------------------------------UGCAGUCCAUGGGCAUAUACACa--------------------- 2 -1,0 ----------------------------------------------------UGCAGUCCAUGGGCAUAUACACc--------------------- 6 -1,0 ----------------------------------------------------UGCAGUCCAUGGGCAUAUACACU--------------------- 4 -1,1 -----------------------------------------------------GCAGUCCAUGGGCAUAUA------------------------- 48 0,-3 -----------------------------------------------------GCAGUCCAUGGGCAUAUAa------------------------ 19 0,-3 -----------------------------------------------------GCAGUCCAUGGGCAUAUAaa----------------------- 9 0,-3 -----------------------------------------------------GCAGUCCAUGGGCAUAUAg------------------------ 2 0,-3 -----------------------------------------------------GCAGUCCAUGGGCAUAUAu------------------------ 10 0,-3 -----------------------------------------------------GCAGUCCAUGGGCAUAUAC------------------------ 217 0,-2 -----------------------------------------------------GCAGUCCAUGGGCAUAUACu----------------------- 4 0,-2 -----------------------------------------------------GCAGUCCAUGGGCAUAUACA----------------------- 1192 0,-1 -----------------------------------------------------GCAGUCCAUGGGCAUAUACAa---------------------- 46 0,-1 -----------------------------------------------------GCAGUCCAUGGGCAUAUACAu---------------------- 5 0,-1 -----------------------------------------------------GCAGUCCAUGGGCAUAUACAuu--------------------- 6 0,-1 -----------------------------------------------------GCAGUCCAUGGGCAUAUACAC---------------------- 1393 0,0 -----------------------------------------------------GCAGUCCAUGGGCAUAUACACa--------------------- 56 0,0 -----------------------------------------------------GCAGUCCAUGGGCAUAUACACc--------------------- 803 0,0 -----------------------------------------------------GCAGUCCAUGGGCAUAUACACU--------------------- 999 0,1 -----------------------------------------------------GCAGUCCAUGGGCAUAUACACUU-------------------- 4 0,2 ------------------------------------------------------CAGUCCAUGGGCAUAUACA----------------------- 8 1,-1 ------------------------------------------------------CAGUCCAUGGGCAUAUACAC---------------------- 50 1,0 ------------------------------------------------------CAGUCCAUGGGCAUAUACACc--------------------- 45 1,0 ------------------------------------------------------CAGUCCAUGGGCAUAUACACU--------------------- 32 1,1 ------------------------------------------------------CAGUCCAUGGGCAUAUACACUU-------------------- 23 1,2 -------------------------------------------------------AGUCCAUGGGCAUAUACA----------------------- 3 2,-1 -------------------------------------------------------AGUCCAUGGGCAUAUACACc--------------------- 2 2,0 -------------------------------------------------------AGUCCAUGGGCAUAUACACU--------------------- 2 2,1 >hsa-mir-4636 5pM:10-31 Tumor uagauucagAACUCGUGUUCAAAGCCUUUAGcccagcaaugggagagugcuaaaggcuucaagcacgaguucugaaucua ---------AACUCGUGUUCAAAGCCUUUAG------------------------------------------------- 5 0,0 ---------AACUCGUGUUCAAAGCCUUUAGa------------------------------------------------ 2 0,0 >hsa-mir-4639 5p:10-31;3p:57-76 Tumor acugugaaaUUGCUAAGUAGGCUGAGAUUGAugucagguuauccccaagcauaaccUCACUCUCACCUUGCUUUGCaggcauau ----------UGCUAAGUAGGCUGAGAUUGA----------------------------------------------------- 2 1,0 >hsa-mir-4649 5p:10-33;3p:50-70 Tumor cccauugucUGGGCGAGGGGUGGGCUCUCAGAGgggcuggcaguacugcUCUGAGGCCUGCCUCUCCCCAgaccuuucauggg --------------------------------------------------CUGAGGCCUGCCUCUCCCCAGu----------- 8 1,1 >hsa-mir-4651 5pM:10-29 Tumor cggcgacggCGGGGUGGGUGAGGUCGGGCcccaagacucgggguuugccgggcgccucaguucaccgcggccg ----------GGGGUGGGUGAGGUCGGG--------------------------------------------- 2 1,-1 >hsa-mir-4654 5pM:10-31 Tumor cuggcugguUGUGGGAUCUGGAGGCAUCUGGgguuggaaugugaccccagucuccuuuucccucaucaucugccag ---------UGUGGGAUCUGGAGGCAUCU----------------------------------------------- 2 0,-2 >hsa-mir-4658 3pM:37-59 Tumor gcugcccuucacucagagcaucuacacccacuaccgGUGAGUGUGGAUCCUGGAGGAAUcguggc ------------------------------------GUGAGUGUGGAUCCUGGAGGAAU------ 2 0,0 >hsa-mir-4659a 5p:14-35;3p:49-70 Tumor gaaacugcugaagCUGCCAUGUCUAAGAAGAAAACuuuggagaaaaauUUUCUUCUUAGACAUGGCAACGucaacaguuuc -------------CUGCCAUGUCUAAGAAGAAAACU--------------------------------------------- 2 0,1 >hsa-mir-466 3pM:52-74 Tumor guguguguauauguguguugcauguguguauauguguguauauauguacacAUACACAUACACGCAACACACAUauauacaugc -------------UGUGUUGCAUGUGUGUAUAUG-------------------------------------------------- 2 -------------UGUGUUGCAUGUGUGUAUAUGU------------------------------------------------- 18 ---------------------------------------------------AUACACAUACACGCAACACACA----------- 5 0,-1 >hsa-mir-4660 5pM:9-31 Tumor acuccuucUGCAGCUCUGGUGGAAAAUGGAGaagacuuuuccuuuccuccaucucccccagggccugguggagu --------UGCAGCUCUGGUGGAAAAUGGAu------------------------------------------- 2 0,-1 >hsa-mir-4661 5p:10-31;3p:47-68 Tumor uuuacucugAACUAGCUCUGUGGAUCCUGACagacagccugauagaCAGGAUCCACAGAGCUAGUCCAgaguaaa ---------AACUAGCUCUGUGGAUCCUGA--------------------------------------------- 8 0,-1 ---------AACUAGCUCUGUGGAUCCUGAC-------------------------------------------- 5 0,0 >hsa-mir-4662a 5p:6-27;3p:43-64 Tumor ucuauUUAGCCAAUUGUCCAUCUUUAGcuauucugaaugccuAAAGAUAGACAAUUGGCUAAAUaga -----UUAGCCAAUUGUCCAUCUUU------------------------------------------ 8 0,-2 -----UUAGCCAAUUGUCCAUCUUUA----------------------------------------- 4 0,-1 -----UUAGCCAAUUGUCCAUCUUUAG---------------------------------------- 83 0,0 -----UUAGCCAAUUGUCCAUCUUUAGa--------------------------------------- 5 0,0 -----UUAGCCAAUUGUCCAUCUUUAGu--------------------------------------- 4 0,0 ------------------------------------------AAAGAUAGACAAUUGGCUAAA---- 3 0,-1 ------------------------------------------AAAGAUAGACAAUUGGCUAAAU--- 17 0,0 >hsa-mir-4664 5p:10-31;3p:44-65 Tumor guugggggcUGGGGUGCCCACUCCGCAAGUUaucacugagcgaCUUCCGGUCUGUGAGCCCCGUCcuccgc ---------UGGGGUGCCCACUCCGCA-------------------------------------------- 2 0,-4 ---------UGGGGUGCCCACUCCGCAAG------------------------------------------ 2 0,-2 ---------UGGGGUGCCCACUCCGCAAGU----------------------------------------- 38 0,-1 ---------UGGGGUGCCCACUCCGCAAGUa---------------------------------------- 2 0,-1 ---------UGGGGUGCCCACUCCGCAAGUU---------------------------------------- 239 0,0 ---------UGGGGUGCCCACUCCGCAAGUUu--------------------------------------- 6 0,0 ---------UGGGGUGCCCACUCCGCAAGUUA--------------------------------------- 3 0,1 ----------GGGGUGCCCACUCCGCAAGUU---------------------------------------- 7 1,0 -------------------------------------------CUUCCGGUCUGUGAGCCCCGUC------ 2 0,0 >hsa-mir-4674 3pM:58-78 Tumor cccaggcgcccgcucccgacccacgccgcgccgccgggucccuccuccccggagaggCUGGGCUCGGGACGCGCGGCUcagcucggg ----------------------------------------------------------UGGGCUCGGGACGCGCGGCUC-------- 2 1,1 >hsa-mir-4677 5p:13-34;3p:50-71 Tumor gcaaagcagcaaUUGUUCUUUGGUCUUUCAGCCAugaccugaccuucugUCUGUGAGACCAAAGAACUACUuugcuuggc ------------UUGUUCUUUGGUCUUUCAGCC----------------------------------------------- 2 0,-1 -------------------------------------------------UCUGUGAGACCAAAGAACUA----------- 2 0,-2 -------------------------------------------------UCUGUGAGACCAAAGAACUACU--------- 37 0,0 >hsa-mir-4690 5p:1-22;3p:39-59 Tumor GAGCAGGCGAGGCUGGGCUGAAcccgugggugaggaguGCAGCCCAGCUGAGGCCUCUGc --------------------------------------GCAGCCCAGCUGAGGCCUCUGCu 2 0,1 >hsa-mir-4705 5pM:10-31 Tumor cucacaagaUCAAUCACUUGGUAAUUGCUGUgauaacaacucagcaauuaccaagugauugguuuugugag ---------UCAAUCACUUGGUAAUUGCUGU---------------------------------------- 2 0,0 >hsa-mir-4707 5p:10-32;3p:52-73 Tumor gguuccggaGCCCCGGCGCGGGCGGGUUCUGGgguguagacgcugcuggccAGCCCGCCCCAGCCGAGGUUCUcggcacc ---------------------------------------------------AGCCCGCCCCAGCCGAGGUU--------- 18 0,-2 ---------------------------------------------------AGCCCGCCCCAGCCGAGGUUCU------- 16 0,0 >hsa-mir-4714 5p:10-31;3p:48-69 Tumor auuuuggccAACUCUGACCCCUUAGGUUGAUgucagaaugagguguaCCAACCUAGGUGGUCAGAGUUGgccaaaau ---------AACUCUGACCCCUUAGGUUGAU---------------------------------------------- 3 0,0 ----------ACUCUGACCCCUUAGGUUGAU---------------------------------------------- 2 1,0 -----------------------------------------------CCAACCUAGGUGGUCAGAGUUG-------- 2 0,0 >hsa-mir-4724 5p:11-33;3p:59-79 Tumor acgcaaaaugAACUGAACCAGGAGUGAGCUUCGuguacauuaucuauuagaaaaugaaGUACCUUCUGGUUCAGCUAGUcccugugcgu ----------AACUGAACCAGGAGUGAGCU----------------------------------------------------------- 7 0,-3 ----------AACUGAACCAGGAGUGAGCUU---------------------------------------------------------- 4 0,-2 ----------AACUGAACCAGGAGUGAGCUUCG-------------------------------------------------------- 10 0,0 --------------------------------------------------------AAGUACCUUCUGGUUCAGCU------------- 2 -2,-3 --------------------------------------------------------AAGUACCUUCUGGUUCAGCUAGU---------- 2 -2,0 >hsa-mir-4726 5p:1-23;3p:37-58 Tumor AGGGCCAGAGGAGCCUGGAGUGGucgggucgacugaACCCAGGUUCCCUCUGGCCGCA AGGGCCAGAGGAGCCUGGAGU------------------------------------- 8 0,-2 AGGGCCAGAGGAGCCUGGAGUGG----------------------------------- 2 0,0 >hsa-mir-4728 5p:18-40;3p:59-83 Tumor ccagacuggagggggagUGGGAGGGGAGAGGCAGCAAGCAcacagggccugggacuagCAUGCUGACCUCCCUCCUGCCCCAGguugg -----------------UGGGAGGGGAGAGGCAGCAAG-------------------------------------------------- 2 0,-2 -----------------UGGGAGGGGAGAGGCAGCAAGu------------------------------------------------- 2 0,-2 -----------------UGGGAGGGGAGAGGCAGCAAGC------------------------------------------------- 2 0,-1 ----------------------------------------------------------CAUGCUGACCUCCCUCCUGC---------- 45 0,-5 ----------------------------------------------------------CAUGCUGACCUCCCUCCUGCu--------- 2 0,-5 ----------------------------------------------------------CAUGCUGACCUCCCUCCUGCC--------- 88 0,-4 ----------------------------------------------------------CAUGCUGACCUCCCUCCUGCCa-------- 2 0,-4 ----------------------------------------------------------CAUGCUGACCUCCCUCCUGCCC-------- 4 0,-3 ----------------------------------------------------------CAUGCUGACCUCCCUCCUGCCCCA------ 25 0,-1 ----------------------------------------------------------CAUGCUGACCUCCCUCCUGCCCCAu----- 9 0,-1 ----------------------------------------------------------CAUGCUGACCUCCCUCCUGCCCCAG----- 16 0,0 -----------------------------------------------------------AUGCUGACCUCCCUCCUGCC--------- 8 1,-4 -----------------------------------------------------------AUGCUGACCUCCCUCCUGCCCCA------ 3 1,-1 -----------------------------------------------------------AUGCUGACCUCCCUCCUGCCCCAG----- 3 1,0 -----------------------------------------------------------AUGCUGACCUCCCUCCUGCCCCAGu---- 38 1,0 >hsa-mir-4742 5p:1-23;3p:63-85 Tumor UCAGGCAAAGGGAUAUUUACAGAuacuuuuuaaaauuuguuugaguugaggcagauuaaauaUCUGUAUUCUCCUUUGCCUGCAG --------------------------------------------------------------UCUGUAUUCUCCUUUGCCUGCA- 2 0,-1 ----------------------------------------------------------------UGUAUUCUCCUUUGCCUGCAGu 2 2,0 >hsa-mir-4746 5p:10-32;3p:44-64 Tumor gugucugugCCGGUCCCAGGAGAACCUGCAGAggcaucgggucAGCGGUGCUCCUGCGGGCCGAcacucac ---------CCGGUCCCAGGAGAACCUGCAGA--------------------------------------- 2 0,0 >hsa-mir-4747 5p:1-22;3p:33-54 Tumor AGGGAAGGAGGCUUGGUCUUAGcacggggucuAAGGCCCGGGCUUUCCUCCCAG --------------------------------AAGGCCCGGGCUUUCCUCCCAGa 2 0,0 >hsa-mir-4758 5p:5-27;3p:49-71 Tumor acagGUGAGUGGGAGCCGGUGGGGCUGgaguaagggcacgcccggggcUGCCCCACCUGCUGACCACCCUCcccccacagcacccugu ------------------------------------------------UGCCCCACCUGCUGACCACC-------------------- 2 0,-3 >hsa-mir-4767 5pM:10-32 Tumor acaugggccCGCGGGCGCUCCUGGCCGCCGCCcgacuucggggccagccgggggcagagcgcgcgggagcccgagcgu ---------CGCGGGCGCUCCUGGCCGCCGC----------------------------------------------- 2 0,-1 >hsa-mir-4772 5p:12-33;3p:48-69 Tumor gugauugccucUGAUCAGGCAAAAUUGCAGACUgucuucccaaauagCCUGCAACUUUGCCUGAUCAGAggcagucac ---------UCUGAUCAGGCAAAAUUGCAGA----------------------------------------------- 4 -2,-2 -----------UGAUCAGGCAAAAUUGCAGA----------------------------------------------- 2 0,-2 -----------UGAUCAGGCAAAAUUGCAGAC---------------------------------------------- 2 0,-1 -----------UGAUCAGGCAAAAUUGCAGACU--------------------------------------------- 19 0,0 -----------------------------------------------CCUGCAACUUUGCCUGAUCAGA--------- 45 0,0 >hsa-mir-4777 5p:16-37;3p:57-78 Tumor uagaauauuucggcaUUCUAGAUGAGAGAUAUAUAUAuaccucauauguauaugguAUACCUCAUCUAGAAUGCUGUAauauucua --------------------------------------------------------AUACCUCAUCUAGAAUGCUGUA-------- 2 0,0 >hsa-mir-4781 5p:13-33;3p:46-67 Tumor aggugcacgcucUAGCGGGGAUUCCAAUAUUGGgccaauucccccAAUGUUGGAAUCCUCGCUAGAGcgugcacuu -----------------------------------------------UGUUGGAAUCCUCGCUAGAGCGU------ 2 2,3 >hsa-mir-4789 5p:13-34;3p:51-71 Tumor caugcuacguauGUAUACACCUGAUAUGUGUAUGuguaaauacauauccaCACACAUAGCAGGUGUAUAUAuagguagccug -----------UGUAUACACCUGAUAUGUGUAU------------------------------------------------- 8 -1,-1 --------------------------------------------------CACACAUAGCAGGUGUAUAUAU---------- 11 0,1 >hsa-mir-4790 5p:10-29;3p:55-76 Tumor caaugugacAUCGCUUUACCAUUCAUGUUcacugaaagguagauuuuaaaaacaUGAAUGGUAAAGCGAUGUCACAuug --------------------------------------------------------AAUGGUAAAGCGAUGUCACAU-- 2 2,1 >hsa-mir-4791 5pM:8-25 Tumor uaagaacUGGAUAUGAUGACUGAAAuaagcuccauaucaaugagaauuucaaugggauuaugugcagucaauguccaguaauua -------UGGAUAUGAUGACUGAAA----------------------------------------------------------- 2 0,0 -------UGGAUAUGAUGACUGAAAa---------------------------------------------------------- 2 0,0 -------UGGAUAUGAUGACUGAAAaa--------------------------------------------------------- 4 0,0 >hsa-mir-4802 5p:13-34;3p:47-69 Tumor cugacuggcuugUAUGGAGGUUCUAGACCAUGUUaguguucaagucUACAUGGAUGGAAACCUUCAAGCaggccaagcag ------------UAUGGAGGUUCUAGACCAUGU----------------------------------------------- 11 0,-1 ------------UAUGGAGGUUCUAGACCAUGUU---------------------------------------------- 14 0,0 -------------AUGGAGGUUCUAGACCAUGUU---------------------------------------------- 4 1,0 ----------------------------------------------UACAUGGAUGGAAACCUUCA-------------- 2 0,-3 ----------------------------------------------UACAUGGAUGGAAACCUUCAAG------------ 8 0,-1 ----------------------------------------------UACAUGGAUGGAAACCUUCAAGC----------- 16 0,0 >hsa-mir-483 5p:8-29;3p:48-68 Tumor gagggggAAGACGGGAGGAAAGAAGGGAGugguuccaucacgccuccUCACUCCUCUCCUCCCGUCUUcuccucuc -------AAGACGGGAGGAAAGAAGGGA------------------------------------------------ 9 0,-1 -------AAGACGGGAGGAAAGAAGGGAG----------------------------------------------- 25 0,0 -------AAGACGGGAGGAAAGAAGGGAGa---------------------------------------------- 4 0,0 --------AGACGGGAGGAAAGAAGGGAGU---------------------------------------------- 2 1,1 -----------------------------------------------UCACUCCUCUCCUCCCGUCU--------- 2 0,-1 -----------------------------------------------UCACUCCUCUCCUCCCGUCUUa------- 2 0,0 -----------------------------------------------UCACUCCUCUCCUCCCGUCUUau------ 2 0,0 -----------------------------------------------UCACUCCUCUCCUCCCGUCUUu------- 2 0,0 -----------------------------------------------UCACUCCUCUCCUCCCGUCUUC------- 7 0,1 ------------------------------------------------CACUCCUCUCCUCCCGUCU--------- 2 1,-1 ------------------------------------------------CACUCCUCUCCUCCCGUCUUC------- 4 1,1 ------------------------------------------------CACUCCUCUCCUCCCGUCUUCU------ 20 1,2 >hsa-mir-484 5pM:8-29 Tumor agccucgUCAGGCUCAGUCCCCUCCCGAUaaaccccuaaauagggacuuucccggggggugacccuggcuuuuuuggcg -------UCAGGCUCAGUCCCCUCC------------------------------------------------------ 8 0,-4 -------UCAGGCUCAGUCCCCUCCC----------------------------------------------------- 123 0,-3 -------UCAGGCUCAGUCCCCUCCCa---------------------------------------------------- 5 0,-3 -------UCAGGCUCAGUCCCCUCCCaa--------------------------------------------------- 8 0,-3 -------UCAGGCUCAGUCCCCUCCCau--------------------------------------------------- 5 0,-3 -------UCAGGCUCAGUCCCCUCCCG---------------------------------------------------- 443 0,-2 -------UCAGGCUCAGUCCCCUCCCGc--------------------------------------------------- 15 0,-2 -------UCAGGCUCAGUCCCCUCCCGu--------------------------------------------------- 86 0,-2 -------UCAGGCUCAGUCCCCUCCCGuu-------------------------------------------------- 416 0,-2 -------UCAGGCUCAGUCCCCUCCCGA--------------------------------------------------- 1358 0,-1 -------UCAGGCUCAGUCCCCUCCCGAa-------------------------------------------------- 227 0,-1 -------UCAGGCUCAGUCCCCUCCCGAaa------------------------------------------------- 233 0,-1 -------UCAGGCUCAGUCCCCUCCCGAau------------------------------------------------- 81 0,-1 -------UCAGGCUCAGUCCCCUCCCGAc-------------------------------------------------- 4 0,-1 -------UCAGGCUCAGUCCCCUCCCGAg-------------------------------------------------- 8 0,-1 -------UCAGGCUCAGUCCCCUCCCGAU-------------------------------------------------- 4829 0,0 -------UCAGGCUCAGUCCCCUCCCGAUc------------------------------------------------- 4 0,0 -------UCAGGCUCAGUCCCCUCCCGAUg------------------------------------------------- 19 0,0 -------UCAGGCUCAGUCCCCUCCCGAUu------------------------------------------------- 1254 0,0 -------UCAGGCUCAGUCCCCUCCCGAUuu------------------------------------------------ 86 0,0 -------UCAGGCUCAGUCCCCUCCCGAUA------------------------------------------------- 837 0,1 -------UCAGGCUCAGUCCCCUCCCGAUAg------------------------------------------------ 16 0,1 -------UCAGGCUCAGUCCCCUCCCGAUAu------------------------------------------------ 102 0,1 -------UCAGGCUCAGUCCCCUCCCGAUAuu----------------------------------------------- 2 0,1 -------UCAGGCUCAGUCCCCUCCCGAUAA------------------------------------------------ 74 0,2 -------UCAGGCUCAGUCCCCUCCCGAUAAg----------------------------------------------- 2 0,2 -------UCAGGCUCAGUCCCCUCCCGAUAAu----------------------------------------------- 3 0,2 -------UCAGGCUCAGUCCCCUCCCGAUAAA----------------------------------------------- 2 0,3 --------CAGGCUCAGUCCCCUCCC----------------------------------------------------- 4 1,-3 --------CAGGCUCAGUCCCCUCCCGA--------------------------------------------------- 7 1,-1 --------CAGGCUCAGUCCCCUCCCGAU-------------------------------------------------- 91 1,0 --------CAGGCUCAGUCCCCUCCCGAUu------------------------------------------------- 11 1,0 --------CAGGCUCAGUCCCCUCCCGAUA------------------------------------------------- 14 1,1 --------CAGGCUCAGUCCCCUCCCGAUAu------------------------------------------------ 2 1,1 --------CAGGCUCAGUCCCCUCCCGAUAA------------------------------------------------ 3 1,2 ---------AGGCUCAGUCCCCUCCCGuu-------------------------------------------------- 4 2,-2 ---------AGGCUCAGUCCCCUCCCGAU-------------------------------------------------- 24 2,0 ---------AGGCUCAGUCCCCUCCCGAUu------------------------------------------------- 6 2,0 ---------AGGCUCAGUCCCCUCCCGAUA------------------------------------------------- 2 2,1 >hsa-mir-485 5p:9-30;3p:46-67 Tumor acuuggagAGAGGCUGGCCGUGAUGAAUUCgauucaucaaagcgaGUCAUACACGGCUCUCCUCUCUuuuagu --------AGAGGCUGGCCGUGAUGAAU--------------------------------------------- 30 0,-2 --------AGAGGCUGGCCGUGAUGAAUU-------------------------------------------- 2 0,-1 --------AGAGGCUGGCCGUGAUGAAUUC------------------------------------------- 22 0,0 --------AGAGGCUGGCCGUGAUGAAUUCG------------------------------------------ 74 0,1 --------AGAGGCUGGCCGUGAUGAAUUCGu----------------------------------------- 4 0,1 --------------------------------------------AGUCAUACACGGCUCUCCUCUCU------ 10 -1,0 ---------------------------------------------GUCAUACACGGCUCUCCUCU-------- 2 0,-2 ---------------------------------------------GUCAUACACGGCUCUCCUCUCc------ 2 0,-1 ---------------------------------------------GUCAUACACGGCUCUCCUCUCU------ 78 0,0 ---------------------------------------------GUCAUACACGGCUCUCCUCUCUa----- 2 0,0 >hsa-mir-486 5p:4-25;3p:46-66 Tumor gcaUCCUGUACUGAGCUGCCCCGAGgcccuucaugcugcccagcuCGGGGCAGCUCAGUACAGGAUac --AUCCUGUACUGAGCUGCCCCGA-------------------------------------------- 2 -1,-1 ---UCCUGUACUGAGCUGCCC----------------------------------------------- 2 0,-4 ---UCCUGUACUGAGCUGCCCCG--------------------------------------------- 16 0,-2 ---UCCUGUACUGAGCUGCCCCGc-------------------------------------------- 2 0,-2 ---UCCUGUACUGAGCUGCCCCGA-------------------------------------------- 334 0,-1 ---UCCUGUACUGAGCUGCCCCGAa------------------------------------------- 13 0,-1 ---UCCUGUACUGAGCUGCCCCGAG------------------------------------------- 540 0,0 ---UCCUGUACUGAGCUGCCCCGAGa------------------------------------------ 229 0,0 ---UCCUGUACUGAGCUGCCCCGAGu------------------------------------------ 92 0,0 -----CUGUACUGAGCUGCCCCGAG------------------------------------------- 4 2,0 ---------------------------------------------CGGGGCAGCUCAGUACAGGAU-- 17 0,0 ---------------------------------------------CGGGGCAGCUCAGUACAGGAUA- 2 0,1 >hsa-mir-487a 3pM:49-70 Tumor gguacuugaagagugguuaucccugcuguguucgcuuaauuuaugacgAAUCAUACAGGGACAUCCAGUUuuucaguauc ------------GUGGUUAUCCCUGCUGUGUUCG---------------------------------------------- 39 ------------------------------------------------AAUCAUACAGGGACAUCCAGU----------- 4 0,-1 ------------------------------------------------AAUCAUACAGGGACAUCCAGUU---------- 128 0,0 ------------------------------------------------AAUCAUACAGGGACAUCCAGUUa--------- 2 0,0 ------------------------------------------------AAUCAUACAGGGACAUCCAGUUU--------- 4 0,1 >hsa-mir-487b 3pM:51-72 Tumor uugguacuuggagagugguuaucccuguccuguucguuuugcucaugucgAAUCGUACAGGGUCAUCCACUUuuucaguaucaa --------------------------------------------------AAUCGUACAGGGUCAUCC---------------- 4 0,-4 --------------------------------------------------AAUCGUACAGGGUCAUCCA--------------- 2 0,-3 --------------------------------------------------AAUCGUACAGGGUCAUCCAC-------------- 7 0,-2 --------------------------------------------------AAUCGUACAGGGUCAUCCACU------------- 199 0,-1 --------------------------------------------------AAUCGUACAGGGUCAUCCACUU------------ 492 0,0 --------------------------------------------------AAUCGUACAGGGUCAUCCACUUa----------- 2 0,0 --------------------------------------------------AAUCGUACAGGGUCAUCCACUUaa---------- 2 0,0 --------------------------------------------------AAUCGUACAGGGUCAUCCACUUU----------- 84 0,1 ---------------------------------------------------AUCGUACAGGGUCAUCCACU------------- 2 1,-1 ---------------------------------------------------AUCGUACAGGGUCAUCCACUU------------ 19 1,0 ---------------------------------------------------AUCGUACAGGGUCAUCCACUUU----------- 52 1,1 ----------------------------------------------------UCGUACAGGGUCAUCCACUU------------ 13 2,0 ----------------------------------------------------UCGUACAGGGUCAUCCACUUa----------- 2 2,0 ----------------------------------------------------UCGUACAGGGUCAUCCACUUU----------- 68 2,1 ----------------------------------------------------UCGUACAGGGUCAUCCACUUUU---------- 6 2,2 >hsa-mir-488 mi:14-34;MA:52-72 Tumor gagaaucaucucuCCCAGAUAAUGGCACUCUCAAacaaguuuccaaauuguUUGAAAGGCUAUUUCUUGGUCagaugacucuc --------------------------------------------------UUUGAAAGGCUAUUUCUUGG------------- 2 -1,-2 --------------------------------------------------UUUGAAAGGCUAUUUCUUGGUa----------- 2 -1,-1 --------------------------------------------------UUUGAAAGGCUAUUUCUUGGUC----------- 8 -1,0 ---------------------------------------------------UUGAAAGGCUAUUUCUUGGU------------ 7 0,-1 ---------------------------------------------------UUGAAAGGCUAUUUCUUGGUa----------- 4 0,-1 ---------------------------------------------------UUGAAAGGCUAUUUCUUGGUaa---------- 4 0,-1 ---------------------------------------------------UUGAAAGGCUAUUUCUUGGUC----------- 70 0,0 ---------------------------------------------------UUGAAAGGCUAUUUCUUGGUCu---------- 159 0,0 ---------------------------------------------------UUGAAAGGCUAUUUCUUGGUCA---------- 10 0,1 >hsa-mir-489 3pM:52-73 Tumor guggcagcuugguggucguaugugugacgccauuuacuugaaccuuuaggaGUGACAUCACAUAUACGGCAGCuaaacugcuac ---------------------------------------------------GUGACAUCACAUAUACGGCAG------------ 14 0,-1 ---------------------------------------------------GUGACAUCACAUAUACGGCAGC----------- 18 0,0 ---------------------------------------------------GUGACAUCACAUAUACGGCAGCa---------- 2 0,0 >hsa-mir-490 5p:39-58;3p:76-97 Tumor uggaggccuugcugguuuggaaaguucauuguucgacaCCAUGGAUCUCCAGGUGGGUcaaguuuagagaugcacCAACCUGGAGGACUCCAUGCUGuugagcuguucacaagcagcggacacuucca ---------------------------------------------------------------------------CAACCUGGAGGACUCCAUGCUGU------------------------------ 4 0,1 >hsa-mir-491 5p:16-37;3p:50-71 Tumor uugacuuagcuggguAGUGGGGAACCCUUCCAUGAGGaguagaacacucCUUAUGCAAGAUUCCCUUCUACcuggcuggguugg ---------------AGUGGGGAACCCUUCCAUGA------------------------------------------------- 8 0,-2 ---------------AGUGGGGAACCCUUCCAUGAaa----------------------------------------------- 2 0,-2 ---------------AGUGGGGAACCCUUCCAUGAG------------------------------------------------ 23 0,-1 ---------------AGUGGGGAACCCUUCCAUGAGa----------------------------------------------- 10 0,-1 ---------------AGUGGGGAACCCUUCCAUGAGu----------------------------------------------- 2 0,-1 ---------------AGUGGGGAACCCUUCCAUGAGG----------------------------------------------- 302 0,0 ---------------AGUGGGGAACCCUUCCAUGAGGu---------------------------------------------- 2 0,0 ---------------AGUGGGGAACCCUUCCAUGAGGA---------------------------------------------- 387 0,1 ---------------AGUGGGGAACCCUUCCAUGAGGAa--------------------------------------------- 70 0,1 ---------------AGUGGGGAACCCUUCCAUGAGGAau-------------------------------------------- 2 0,1 ---------------AGUGGGGAACCCUUCCAUGAGGAu--------------------------------------------- 8 0,1 -----------------UGGGGAACCCUUCCAUGAGGAa--------------------------------------------- 2 2,1 -----------------UGGGGAACCCUUCCAUGAGGAG--------------------------------------------- 4 2,2 -----------------UGGGGAACCCUUCCAUGAGGAGU-------------------------------------------- 4 2,3 -------------------------------------------------CUUAUGCAAGAUUCCCUUCU--------------- 4 0,-2 -------------------------------------------------CUUAUGCAAGAUUCCCUUCUAu------------- 4 0,-1 -------------------------------------------------CUUAUGCAAGAUUCCCUUCUAC------------- 2 0,0 >hsa-mir-493 mi:16-37;MA:57-78 Tumor cuggccuccagggcuUUGUACAUGGUAGGCUUUCAUUcauucguuugcacauucggUGAAGGUCUACUGUGUGCCAGGcccugugccag ---------------UUGUACAUGGUAGGCUUUC------------------------------------------------------- 2 0,-3 ---------------UUGUACAUGGUAGGCUUUCA------------------------------------------------------ 15 0,-2 ---------------UUGUACAUGGUAGGCUUUCAU----------------------------------------------------- 61 0,-1 ---------------UUGUACAUGGUAGGCUUUCAUa---------------------------------------------------- 2 0,-1 ---------------UUGUACAUGGUAGGCUUUCAUU---------------------------------------------------- 457 0,0 ---------------UUGUACAUGGUAGGCUUUCAUUa--------------------------------------------------- 12 0,0 ---------------UUGUACAUGGUAGGCUUUCAUUu--------------------------------------------------- 2 0,0 ----------------UGUACAUGGUAGGCUUUCAUU---------------------------------------------------- 8 1,0 --------------------------------------------------------UGAAGGUCUACUGUGUGCCA------------- 9 0,-2 --------------------------------------------------------UGAAGGUCUACUGUGUGCCAa------------ 2 0,-2 --------------------------------------------------------UGAAGGUCUACUGUGUGCCAG------------ 40 0,-1 --------------------------------------------------------UGAAGGUCUACUGUGUGCCAGa----------- 13 0,-1 --------------------------------------------------------UGAAGGUCUACUGUGUGCCAGu----------- 86 0,-1 --------------------------------------------------------UGAAGGUCUACUGUGUGCCAGG----------- 95 0,0 --------------------------------------------------------UGAAGGUCUACUGUGUGCCAGGa---------- 12 0,0 --------------------------------------------------------UGAAGGUCUACUGUGUGCCAGGu---------- 11 0,0 ---------------------------------------------------------GAAGGUCUACUGUGUGCCAGu----------- 3 1,-1 >hsa-mir-494 3pM:48-69 Tumor gauacucgaaggagagguuguccguguugucuucucuuuauuuaugaUGAAACAUACACGGGAAACCUCuuuuuuaguauc -----------------------------------------------UGAAACAUACACGGGAAAC--------------- 2 0,-3 -----------------------------------------------UGAAACAUACACGGGAAACC-------------- 7 0,-2 -----------------------------------------------UGAAACAUACACGGGAAACCU------------- 78 0,-1 -----------------------------------------------UGAAACAUACACGGGAAACCUC------------ 94 0,0 -----------------------------------------------UGAAACAUACACGGGAAACCUCa----------- 3 0,0 -----------------------------------------------UGAAACAUACACGGGAAACCUCc----------- 2 0,0 -----------------------------------------------UGAAACAUACACGGGAAACCUCU----------- 503 0,1 ------------------------------------------------GAAACAUACACGGGAAACCUCU----------- 9 1,1 >hsa-mir-495 3pM:50-71 Tumor ugguaccugaaaagaaguugcccauguuauuuucgcuuuauaugugacgAAACAAACAUGGUGCACUUCUUuuucgguauca -------------GAAGUUGCCCAUGUUAUUUUCG----------------------------------------------- 10 -------------------------------------------------AAACAAACAUGGUGCACUU-------------- 3 0,-3 -------------------------------------------------AAACAAACAUGGUGCACUUC------------- 2 0,-2 -------------------------------------------------AAACAAACAUGGUGCACUUCU------------ 100 0,-1 -------------------------------------------------AAACAAACAUGGUGCACUUCUU----------- 554 0,0 -------------------------------------------------AAACAAACAUGGUGCACUUCUUa---------- 7 0,0 -------------------------------------------------AAACAAACAUGGUGCACUUCUUU---------- 397 0,1 -------------------------------------------------AAACAAACAUGGUGCACUUCUUUU--------- 10 0,2 --------------------------------------------------AACAAACAUGGUGCACUUCUU----------- 24 1,0 --------------------------------------------------AACAAACAUGGUGCACUUCUUU---------- 66 1,1 --------------------------------------------------AACAAACAUGGUGCACUUCUUUa--------- 2 1,1 ---------------------------------------------------ACAAACAUGGUGCACUUCUUUU--------- 2 2,2 >hsa-mir-496 3pM:56-77 Tumor cccaagucagguacucgaauggagguuguccaugguguguucauuuuauuuaugaUGAGUAUUACAUGGCCAAUCUCcuuucgguacucaauucuucuuggg -------------------------------------------------------UGAGUAUUACAUGGCCAAUCU-------------------------- 4 0,-1 -------------------------------------------------------UGAGUAUUACAUGGCCAAUCUCa------------------------ 2 0,0 ---------------------------------------------------------AGUAUUACAUGGCCAAUCUCC------------------------ 2 2,1 >hsa-mir-497 MA:24-44;mi:64-85 Tumor ccaccccgguccugcucccgcccCAGCAGCACACUGUGGUUUGUacggcacuguggccacgucCAAACCACACUGUGGUGUUAGAgcgagggugggggaggcaccgccgagg ----------------------CCAGCAGCACACUGUGGUUUGU-------------------------------------------------------------------- 16 -1,0 -----------------------CAGCAGCACACUGUGGUU----------------------------------------------------------------------- 152 0,-3 -----------------------CAGCAGCACACUGUGGUUaa--------------------------------------------------------------------- 2 0,-3 -----------------------CAGCAGCACACUGUGGUUU---------------------------------------------------------------------- 305 0,-2 -----------------------CAGCAGCACACUGUGGUUUa--------------------------------------------------------------------- 12 0,-2 -----------------------CAGCAGCACACUGUGGUUUaa-------------------------------------------------------------------- 14 0,-2 -----------------------CAGCAGCACACUGUGGUUUau-------------------------------------------------------------------- 104 0,-2 -----------------------CAGCAGCACACUGUGGUUUu--------------------------------------------------------------------- 13 0,-2 -----------------------CAGCAGCACACUGUGGUUUuu-------------------------------------------------------------------- 233 0,-2 -----------------------CAGCAGCACACUGUGGUUUG--------------------------------------------------------------------- 1468 0,-1 -----------------------CAGCAGCACACUGUGGUUUGa-------------------------------------------------------------------- 800 0,-1 -----------------------CAGCAGCACACUGUGGUUUGaa------------------------------------------------------------------- 57 0,-1 -----------------------CAGCAGCACACUGUGGUUUGau------------------------------------------------------------------- 3 0,-1 -----------------------CAGCAGCACACUGUGGUUUGc-------------------------------------------------------------------- 58 0,-1 -----------------------CAGCAGCACACUGUGGUUUGg-------------------------------------------------------------------- 82 0,-1 -----------------------CAGCAGCACACUGUGGUUUGU-------------------------------------------------------------------- 46016 0,0 -----------------------CAGCAGCACACUGUGGUUUGUc------------------------------------------------------------------- 33 0,0 -----------------------CAGCAGCACACUGUGGUUUGUg------------------------------------------------------------------- 6 0,0 -----------------------CAGCAGCACACUGUGGUUUGUu------------------------------------------------------------------- 445 0,0 -----------------------CAGCAGCACACUGUGGUUUGUuu------------------------------------------------------------------ 12 0,0 -----------------------CAGCAGCACACUGUGGUUUGUA------------------------------------------------------------------- 13289 0,1 -----------------------CAGCAGCACACUGUGGUUUGUAa------------------------------------------------------------------ 4719 0,1 -----------------------CAGCAGCACACUGUGGUUUGUAaa----------------------------------------------------------------- 107 0,1 -----------------------CAGCAGCACACUGUGGUUUGUAau----------------------------------------------------------------- 22 0,1 -----------------------CAGCAGCACACUGUGGUUUGUAg------------------------------------------------------------------ 234 0,1 -----------------------CAGCAGCACACUGUGGUUUGUAu------------------------------------------------------------------ 2511 0,1 -----------------------CAGCAGCACACUGUGGUUUGUAuu----------------------------------------------------------------- 13 0,1 -----------------------CAGCAGCACACUGUGGUUUGUAC------------------------------------------------------------------ 532 0,2 -----------------------CAGCAGCACACUGUGGUUUGUACa----------------------------------------------------------------- 2 0,2 -----------------------CAGCAGCACACUGUGGUUUGUACu----------------------------------------------------------------- 5 0,2 -----------------------CAGCAGCACACUGUGGUUUGUACG----------------------------------------------------------------- 4 0,3 ------------------------AGCAGCACACUGUGGUUU---------------------------------------------------------------------- 8 1,-2 ------------------------AGCAGCACACUGUGGUUUG--------------------------------------------------------------------- 78 1,-1 ------------------------AGCAGCACACUGUGGUUUGa-------------------------------------------------------------------- 20 1,-1 ------------------------AGCAGCACACUGUGGUUUGc-------------------------------------------------------------------- 2 1,-1 ------------------------AGCAGCACACUGUGGUUUGU-------------------------------------------------------------------- 2815 1,0 ------------------------AGCAGCACACUGUGGUUUGUu------------------------------------------------------------------- 2 1,0 ------------------------AGCAGCACACUGUGGUUUGUA------------------------------------------------------------------- 966 1,1 ------------------------AGCAGCACACUGUGGUUUGUAa------------------------------------------------------------------ 434 1,1 ------------------------AGCAGCACACUGUGGUUUGUAaa----------------------------------------------------------------- 6 1,1 ------------------------AGCAGCACACUGUGGUUUGUAg------------------------------------------------------------------ 4 1,1 ------------------------AGCAGCACACUGUGGUUUGUAu------------------------------------------------------------------ 97 1,1 ------------------------AGCAGCACACUGUGGUUUGUAC------------------------------------------------------------------ 1287 1,2 ------------------------AGCAGCACACUGUGGUUUGUACa----------------------------------------------------------------- 36 1,2 ------------------------AGCAGCACACUGUGGUUUGUACu----------------------------------------------------------------- 4 1,2 ------------------------AGCAGCACACUGUGGUUUGUACG----------------------------------------------------------------- 2 1,3 -------------------------GCAGCACACUGUGGUUUGU-------------------------------------------------------------------- 6 2,0 -------------------------GCAGCACACUGUGGUUUGUA------------------------------------------------------------------- 7 2,1 -------------------------GCAGCACACUGUGGUUUGUAu------------------------------------------------------------------ 2 2,1 -------------------------GCAGCACACUGUGGUUUGUAC------------------------------------------------------------------ 15 2,2 -------------------------------------------------------------UCCAAACCACACUGUGGUGUU------------------------------ 6 -2,-3 -------------------------------------------------------------UCCAAACCACACUGUGGUGUUg----------------------------- 2 -2,-3 -------------------------------------------------------------UCCAAACCACACUGUGGUGUUA----------------------------- 3 -2,-2 -------------------------------------------------------------UCCAAACCACACUGUGGUGUUAG---------------------------- 17 -2,-1 --------------------------------------------------------------CCAAACCACACUGUGGUGUU------------------------------ 4 -1,-3 --------------------------------------------------------------CCAAACCACACUGUGGUGUUg----------------------------- 5 -1,-3 --------------------------------------------------------------CCAAACCACACUGUGGUGUUA----------------------------- 4 -1,-2 --------------------------------------------------------------CCAAACCACACUGUGGUGUUAG---------------------------- 70 -1,-1 --------------------------------------------------------------CCAAACCACACUGUGGUGUUAGu--------------------------- 11 -1,-1 --------------------------------------------------------------CCAAACCACACUGUGGUGUUAGA--------------------------- 23 -1,0 ---------------------------------------------------------------CAAACCACACUGUGGUGUU------------------------------ 99 0,-3 ---------------------------------------------------------------CAAACCACACUGUGGUGUUg----------------------------- 2 0,-3 ---------------------------------------------------------------CAAACCACACUGUGGUGUUAG---------------------------- 11 0,-1 ---------------------------------------------------------------CAAACCACACUGUGGUGUUAGA--------------------------- 148 0,0 ---------------------------------------------------------------CAAACCACACUGUGGUGUUAGAa-------------------------- 2 0,0 ----------------------------------------------------------------AAACCACACUGUGGUGUU------------------------------ 5 1,-3 >hsa-mir-499 5p:33-53;3p:70-91 Tumor gcccuguccccugugccuugggcgggcggcugUUAAGACUUGCAGUGAUGUUUaacuccucuccacgugAACAUCACAGCAAGUCUGUGCUgcuucccgucccuacgcugccugggcagggu --------------------------------UUAAGACUUGCAGUGAUGUU---------------------------------------------------------------------- 67 0,-1 --------------------------------UUAAGACUUGCAGUGAUGUUa--------------------------------------------------------------------- 2 0,-1 --------------------------------UUAAGACUUGCAGUGAUGUUU--------------------------------------------------------------------- 944 0,0 --------------------------------UUAAGACUUGCAGUGAUGUUUA-------------------------------------------------------------------- 269 0,1 --------------------------------UUAAGACUUGCAGUGAUGUUUAA------------------------------------------------------------------- 2 0,2 ---------------------------------UAAGACUUGCAGUGAUGUUU--------------------------------------------------------------------- 14 1,0 --------------------------------------------------------------------GAACAUCACAGCAAGUCUGUGC-------------------------------- 4 -1,-1 ---------------------------------------------------------------------AACAUCACAGCAAGUCUGUG--------------------------------- 2 0,-2 ---------------------------------------------------------------------AACAUCACAGCAAGUCUGUGC-------------------------------- 2 0,-1 ---------------------------------------------------------------------AACAUCACAGCAAGUCUGUGCU------------------------------- 4 0,0 >hsa-mir-499a 5p:10-30;3p:46-67 Tumor ggaagcagcACAGACUUGCUGUGAUGUUCAcguggagaggaguuaAACAUCACUGCAAGUCUUAACAgccgcc --------CACAGACUUGCUGUGAUGUUC-------------------------------------------- 2 -1,-1 >hsa-mir-500a MA:13-35;mi:52-73 Tumor gcucccccucucUAAUCCUUGCUACCUGGGUGAGAgugcugucugaaugcaAUGCACCUGGGCAAGGAUUCUGagagcgagagc ------------UAAUCCUUGCUACCUGGGUGA--------------------------------------------------- 16 0,-2 ------------UAAUCCUUGCUACCUGGGUGAG-------------------------------------------------- 135 0,-1 ------------UAAUCCUUGCUACCUGGGUGAGu------------------------------------------------- 15 0,-1 ------------UAAUCCUUGCUACCUGGGUGAGA------------------------------------------------- 562 0,0 ------------UAAUCCUUGCUACCUGGGUGAGAa------------------------------------------------ 3 0,0 ------------UAAUCCUUGCUACCUGGGUGAGAG------------------------------------------------ 51 0,1 ------------UAAUCCUUGCUACCUGGGUGAGAGa----------------------------------------------- 2 0,1 ------------UAAUCCUUGCUACCUGGGUGAGAGU----------------------------------------------- 101 0,2 -------------AAUCCUUGCUACCUGGGUGAGA------------------------------------------------- 2 1,0 --------------------------------------------------AAUGCACCUGGGCAAGGAaa-------------- 2 -1,-5 --------------------------------------------------AAUGCACCUGGGCAAGGAU--------------- 192 -1,-4 --------------------------------------------------AAUGCACCUGGGCAAGGAUa-------------- 11 -1,-4 --------------------------------------------------AAUGCACCUGGGCAAGGAUaa------------- 2 -1,-4 --------------------------------------------------AAUGCACCUGGGCAAGGAUg-------------- 2 -1,-4 --------------------------------------------------AAUGCACCUGGGCAAGGAUU-------------- 1027 -1,-3 --------------------------------------------------AAUGCACCUGGGCAAGGAUUa------------- 3 -1,-3 --------------------------------------------------AAUGCACCUGGGCAAGGAUUaa------------ 4 -1,-3 --------------------------------------------------AAUGCACCUGGGCAAGGAUUC------------- 702 -1,-2 --------------------------------------------------AAUGCACCUGGGCAAGGAUUCc------------ 10 -1,-2 --------------------------------------------------AAUGCACCUGGGCAAGGAUUCg------------ 2 -1,-2 --------------------------------------------------AAUGCACCUGGGCAAGGAUUCU------------ 292 -1,-1 --------------------------------------------------AAUGCACCUGGGCAAGGAUUCUG----------- 6 -1,0 --------------------------------------------------AAUGCACCUGGGCAAGGAUUCUGu---------- 2 -1,0 ---------------------------------------------------AUGCACCUGGGCAAGGAU--------------- 55 0,-4 ---------------------------------------------------AUGCACCUGGGCAAGGAUa-------------- 6 0,-4 ---------------------------------------------------AUGCACCUGGGCAAGGAUU-------------- 193 0,-3 ---------------------------------------------------AUGCACCUGGGCAAGGAUUa------------- 2 0,-3 ---------------------------------------------------AUGCACCUGGGCAAGGAUUaa------------ 2 0,-3 ---------------------------------------------------AUGCACCUGGGCAAGGAUUC------------- 50 0,-2 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCU------------ 573 0,-1 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCUa----------- 2 0,-1 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCUau---------- 2 0,-1 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCUu----------- 3 0,-1 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCUuu---------- 2 0,-1 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCUG----------- 332 0,0 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCUGu---------- 251 0,0 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCUGuu--------- 6 0,0 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCUGA---------- 605 0,1 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCUGAa--------- 4 0,1 ---------------------------------------------------AUGCACCUGGGCAAGGAUUCUGAu--------- 10 0,1 ----------------------------------------------------UGCACCUGGGCAAGGAUU-------------- 2 1,-3 >hsa-mir-500b 5pM:11-28 Tumor cccccucucuAAUCCUUGCUACCUGGGUgagagugcuuucugaaugcagugcacccaggcaaggauucugcaaggggga ---------UAAUCCUUGCUACCUGGGUGA------------------------------------------------- 16 -1,2 ---------UAAUCCUUGCUACCUGGGUGAG------------------------------------------------ 135 -1,3 ---------UAAUCCUUGCUACCUGGGUGAGu----------------------------------------------- 15 -1,3 ---------UAAUCCUUGCUACCUGGGUGAGA----------------------------------------------- 562 -1,4 ---------UAAUCCUUGCUACCUGGGUGAGAa---------------------------------------------- 3 -1,4 ---------UAAUCCUUGCUACCUGGGUGAGAG---------------------------------------------- 51 -1,5 ---------UAAUCCUUGCUACCUGGGUGAGAGa--------------------------------------------- 2 -1,5 ----------AAUCCUUGCUACCUGGGUGAGA----------------------------------------------- 2 0,4 -----------------------------------------------AGUGCACCCAGGCAAGGAUUCU---------- 2 >hsa-mir-501 5p:14-35;3p:51-72 Tumor gcucuuccucucuAAUCCUUUGUCCCUGGGUGAGAgugcuuucugaaugcAAUGCACCCGGGCAAGGAUUCUgagagggugagc -------------AAUCCUUUGUCCCUGGGUGA--------------------------------------------------- 7 0,-2 -------------AAUCCUUUGUCCCUGGGUGAG-------------------------------------------------- 55 0,-1 -------------AAUCCUUUGUCCCUGGGUGAGu------------------------------------------------- 2 0,-1 -------------AAUCCUUUGUCCCUGGGUGAGA------------------------------------------------- 231 0,0 -------------AAUCCUUUGUCCCUGGGUGAGAa------------------------------------------------ 17 0,0 -------------AAUCCUUUGUCCCUGGGUGAGAau----------------------------------------------- 2 0,0 -------------AAUCCUUUGUCCCUGGGUGAGAG------------------------------------------------ 76 0,1 -------------AAUCCUUUGUCCCUGGGUGAGAGa----------------------------------------------- 19 0,1 -------------AAUCCUUUGUCCCUGGGUGAGAGU----------------------------------------------- 274 0,2 -------------AAUCCUUUGUCCCUGGGUGAGAGUu---------------------------------------------- 2 0,2 --------------AUCCUUUGUCCCUGGGUGAGAGU----------------------------------------------- 4 1,2 --------------------------------------------------AAUGCACCCGGGCAAGGAU--------------- 72 0,-3 --------------------------------------------------AAUGCACCCGGGCAAGGAUU-------------- 366 0,-2 --------------------------------------------------AAUGCACCCGGGCAAGGAUUa------------- 2 0,-2 --------------------------------------------------AAUGCACCCGGGCAAGGAUUu------------- 4 0,-2 --------------------------------------------------AAUGCACCCGGGCAAGGAUUuu------------ 12 0,-2 --------------------------------------------------AAUGCACCCGGGCAAGGAUUC------------- 184 0,-1 --------------------------------------------------AAUGCACCCGGGCAAGGAUUCa------------ 19 0,-1 --------------------------------------------------AAUGCACCCGGGCAAGGAUUCc------------ 14 0,-1 --------------------------------------------------AAUGCACCCGGGCAAGGAUUCU------------ 1157 0,0 --------------------------------------------------AAUGCACCCGGGCAAGGAUUCUu----------- 2 0,0 --------------------------------------------------AAUGCACCCGGGCAAGGAUUCUG----------- 88 0,1 --------------------------------------------------AAUGCACCCGGGCAAGGAUUCUGu---------- 6 0,1 ---------------------------------------------------AUGCACCCGGGCAAGGAU--------------- 4 1,-3 ---------------------------------------------------AUGCACCCGGGCAAGGAUU-------------- 11 1,-2 ---------------------------------------------------AUGCACCCGGGCAAGGAUUC------------- 2 1,-1 ---------------------------------------------------AUGCACCCGGGCAAGGAUUCU------------ 41 1,0 >hsa-mir-502 5p:16-36;3p:52-73 Tumor ugcucccccucucuaAUCCUUGCUAUCUGGGUGCUAgugcuggcucaaugcAAUGCACCUGGGCAAGGAUUCAgagagggggagcu -------------UAAUCCUUGCUAUCUGGGUGCU--------------------------------------------------- 8 -2,-1 -------------UAAUCCUUGCUAUCUGGGUGCUAGU------------------------------------------------ 2 -2,2 --------------AAUCCUUGCUAUCUGGGUGCU--------------------------------------------------- 9 -1,-1 --------------AAUCCUUGCUAUCUGGGUGCUAG------------------------------------------------- 16 -1,1 --------------AAUCCUUGCUAUCUGGGUGCUAGa------------------------------------------------ 6 -1,1 --------------AAUCCUUGCUAUCUGGGUGCUAGU------------------------------------------------ 62 -1,2 --------------AAUCCUUGCUAUCUGGGUGCUAGUG----------------------------------------------- 2 -1,3 ---------------------------------------------------AAUGCACCUGGGCAAGGAaa--------------- 2 0,-4 ---------------------------------------------------AAUGCACCUGGGCAAGGAU---------------- 192 0,-3 ---------------------------------------------------AAUGCACCUGGGCAAGGAUa--------------- 11 0,-3 ---------------------------------------------------AAUGCACCUGGGCAAGGAUaa-------------- 2 0,-3 ---------------------------------------------------AAUGCACCUGGGCAAGGAUg--------------- 2 0,-3 ---------------------------------------------------AAUGCACCUGGGCAAGGAUU--------------- 1027 0,-2 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUa-------------- 3 0,-2 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUaa------------- 4 0,-2 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUC-------------- 702 0,-1 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUCc------------- 10 0,-1 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUCg------------- 2 0,-1 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUCA------------- 2025 0,0 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUCAa------------ 43 0,0 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUCAu------------ 8 0,0 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUCAG------------ 389 0,1 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUCAGu----------- 273 0,1 ---------------------------------------------------AAUGCACCUGGGCAAGGAUUCAGA----------- 16 0,2 ----------------------------------------------------AUGCACCUGGGCAAGGAU---------------- 55 1,-3 ----------------------------------------------------AUGCACCUGGGCAAGGAUa--------------- 6 1,-3 ----------------------------------------------------AUGCACCUGGGCAAGGAUU--------------- 193 1,-2 ----------------------------------------------------AUGCACCUGGGCAAGGAUUa-------------- 2 1,-2 ----------------------------------------------------AUGCACCUGGGCAAGGAUUaa------------- 2 1,-2 ----------------------------------------------------AUGCACCUGGGCAAGGAUUC-------------- 50 1,-1 ----------------------------------------------------AUGCACCUGGGCAAGGAUUCA------------- 29 1,0 ----------------------------------------------------AUGCACCUGGGCAAGGAUUCAG------------ 2 1,1 ----------------------------------------------------AUGCACCUGGGCAAGGAUUCAGA----------- 2 1,2 -----------------------------------------------------UGCACCUGGGCAAGGAUU--------------- 2 2,-2 -----------------------------------------------------UGCACCUGGGCAAGGAUUCA------------- 2 2,0 >hsa-mir-503 5pM:6-28 Tumor ugcccUAGCAGCGGGAACAGUUCUGCAGugagcgaucggugcucugggguauuguuuccgcugccagggua -----UAGCAGCGGGAACAGUUC------------------------------------------------ 24 0,-5 -----UAGCAGCGGGAACAGUUCaa---------------------------------------------- 8 0,-5 -----UAGCAGCGGGAACAGUUCU----------------------------------------------- 134 0,-4 -----UAGCAGCGGGAACAGUUCUa---------------------------------------------- 4 0,-4 -----UAGCAGCGGGAACAGUUCUaa--------------------------------------------- 32 0,-4 -----UAGCAGCGGGAACAGUUCUG---------------------------------------------- 319 0,-3 -----UAGCAGCGGGAACAGUUCUGa--------------------------------------------- 120 0,-3 -----UAGCAGCGGGAACAGUUCUGaa-------------------------------------------- 99 0,-3 -----UAGCAGCGGGAACAGUUCUGu--------------------------------------------- 2 0,-3 -----UAGCAGCGGGAACAGUUCUGC--------------------------------------------- 184 0,-2 -----UAGCAGCGGGAACAGUUCUGCc-------------------------------------------- 10 0,-2 -----UAGCAGCGGGAACAGUUCUGCA-------------------------------------------- 871 0,-1 -----UAGCAGCGGGAACAGUUCUGCAa------------------------------------------- 55 0,-1 -----UAGCAGCGGGAACAGUUCUGCAaa------------------------------------------ 6 0,-1 -----UAGCAGCGGGAACAGUUCUGCAau------------------------------------------ 4 0,-1 -----UAGCAGCGGGAACAGUUCUGCAu------------------------------------------- 25 0,-1 -----UAGCAGCGGGAACAGUUCUGCAG------------------------------------------- 1730 0,0 -----UAGCAGCGGGAACAGUUCUGCAGa------------------------------------------ 47 0,0 -----UAGCAGCGGGAACAGUUCUGCAGaa----------------------------------------- 4 0,0 -----UAGCAGCGGGAACAGUUCUGCAGU------------------------------------------ 107 0,1 -----UAGCAGCGGGAACAGUUCUGCAGUu----------------------------------------- 2 0,1 ------AGCAGCGGGAACAGUUCU----------------------------------------------- 4 1,-4 ------AGCAGCGGGAACAGUUCUG---------------------------------------------- 4 1,-3 ------AGCAGCGGGAACAGUUCUGC--------------------------------------------- 5 1,-2 ------AGCAGCGGGAACAGUUCUGCA-------------------------------------------- 31 1,-1 ------AGCAGCGGGAACAGUUCUGCAG------------------------------------------- 60 1,0 ---------------------------------------------GGGGUAUUGUUUCCGCUGCCAGG--- 6 >hsa-mir-504 5pM:13-34 Tumor gcugcuguugggAGACCCUGGUCUGCACUCUAUCuguauucuuacugaagggagugcagggcaggguuucccauacagagggc ------------AGACCCUGGUCUGCACUCU---------------------------------------------------- 15 0,-3 ------------AGACCCUGGUCUGCACUCUA--------------------------------------------------- 13 0,-2 ------------AGACCCUGGUCUGCACUCUAa-------------------------------------------------- 3 0,-2 ------------AGACCCUGGUCUGCACUCUAU-------------------------------------------------- 331 0,-1 ------------AGACCCUGGUCUGCACUCUAUa------------------------------------------------- 3 0,-1 ------------AGACCCUGGUCUGCACUCUAUu------------------------------------------------- 29 0,-1 ------------AGACCCUGGUCUGCACUCUAUC------------------------------------------------- 250 0,0 ------------AGACCCUGGUCUGCACUCUAUCa------------------------------------------------ 11 0,0 ------------AGACCCUGGUCUGCACUCUAUCU------------------------------------------------ 25 0,1 -------------GACCCUGGUCUGCACUCU---------------------------------------------------- 6 1,-3 -------------GACCCUGGUCUGCACUCUA--------------------------------------------------- 4 1,-2 -------------GACCCUGGUCUGCACUCUAa-------------------------------------------------- 2 1,-2 -------------GACCCUGGUCUGCACUCUAU-------------------------------------------------- 189 1,-1 -------------GACCCUGGUCUGCACUCUAUu------------------------------------------------- 2 1,-1 -------------GACCCUGGUCUGCACUCUAUC------------------------------------------------- 134 1,0 -------------GACCCUGGUCUGCACUCUAUCa------------------------------------------------ 2 1,0 -------------GACCCUGGUCUGCACUCUAUCU------------------------------------------------ 18 1,1 -------------GACCCUGGUCUGCACUCUAUCUGU---------------------------------------------- 5 1,3 --------------ACCCUGGUCUGCACUCUAUC------------------------------------------------- 2 2,0 -------------------------------------------------GGGAGUGCAGGGCAGGGUUU-------------- 5 -------------------------------------------------GGGAGUGCAGGGCAGGGUUUCu------------ 2 >hsa-mir-505 mi:15-36;MA:51-72 Tumor gaugcacccaguggGGGAGCCAGGAAGUAUUGAUGUuucugccaguuuagCGUCAACACUUGCUGGUUUCCUcucuggagcauc --------------GGGAGCCAGGAAGUAUUGAUG------------------------------------------------- 7 0,-1 --------------GGGAGCCAGGAAGUAUUGAUGU------------------------------------------------ 25 0,0 --------------GGGAGCCAGGAAGUAUUGAUGUU----------------------------------------------- 143 0,1 --------------GGGAGCCAGGAAGUAUUGAUGUUa---------------------------------------------- 2 0,1 --------------GGGAGCCAGGAAGUAUUGAUGUUU---------------------------------------------- 21 0,2 --------------------------------------------------CGUCAACACUUGCUGGUU---------------- 9 0,-4 --------------------------------------------------CGUCAACACUUGCUGGUUa--------------- 2 0,-4 --------------------------------------------------CGUCAACACUUGCUGGUUU--------------- 199 0,-3 --------------------------------------------------CGUCAACACUUGCUGGUUUu-------------- 6 0,-3 --------------------------------------------------CGUCAACACUUGCUGGUUUC-------------- 265 0,-2 --------------------------------------------------CGUCAACACUUGCUGGUUUCa------------- 4 0,-2 --------------------------------------------------CGUCAACACUUGCUGGUUUCC------------- 295 0,-1 --------------------------------------------------CGUCAACACUUGCUGGUUUCCU------------ 707 0,0 --------------------------------------------------CGUCAACACUUGCUGGUUUCCUu----------- 10 0,0 --------------------------------------------------CGUCAACACUUGCUGGUUUCCUuu---------- 2 0,0 --------------------------------------------------CGUCAACACUUGCUGGUUUCCUC----------- 171 0,1 --------------------------------------------------CGUCAACACUUGCUGGUUUCCUCc---------- 2 0,1 --------------------------------------------------CGUCAACACUUGCUGGUUUCCUCU---------- 389 0,2 --------------------------------------------------CGUCAACACUUGCUGGUUUCCUCUu--------- 2 0,2 ---------------------------------------------------GUCAACACUUGCUGGUUU--------------- 48 1,-3 ---------------------------------------------------GUCAACACUUGCUGGUUUC-------------- 76 1,-2 ---------------------------------------------------GUCAACACUUGCUGGUUUCa------------- 2 1,-2 ---------------------------------------------------GUCAACACUUGCUGGUUUCC------------- 91 1,-1 ---------------------------------------------------GUCAACACUUGCUGGUUUCCU------------ 306 1,0 ---------------------------------------------------GUCAACACUUGCUGGUUUCCUa----------- 2 1,0 ---------------------------------------------------GUCAACACUUGCUGGUUUCCUau---------- 2 1,0 ---------------------------------------------------GUCAACACUUGCUGGUUUCCUu----------- 7 1,0 ---------------------------------------------------GUCAACACUUGCUGGUUUCCUuu---------- 2 1,0 ---------------------------------------------------GUCAACACUUGCUGGUUUCCUC----------- 72 1,1 ---------------------------------------------------GUCAACACUUGCUGGUUUCCUCa---------- 22 1,1 ---------------------------------------------------GUCAACACUUGCUGGUUUCCUCU---------- 493 1,2 ---------------------------------------------------GUCAACACUUGCUGGUUUCCUCUu--------- 4 1,2 ----------------------------------------------------UCAACACUUGCUGGUUUCC------------- 3 2,-1 ----------------------------------------------------UCAACACUUGCUGGUUUCCU------------ 25 2,0 ----------------------------------------------------UCAACACUUGCUGGUUUCCUC----------- 6 2,1 ----------------------------------------------------UCAACACUUGCUGGUUUCCUCa---------- 4 2,1 ----------------------------------------------------UCAACACUUGCUGGUUUCCUCU---------- 114 2,2 ----------------------------------------------------UCAACACUUGCUGGUUUCCUCUu--------- 4 2,2 >hsa-mir-506 3pM:71-91 Tumor gccaccaccaucagccauacuauguguagugccuuauucaggaagguguuacuuaauagauuaauauuugUAAGGCACCCUUCUGAGUAGAguaaugugcaacauggacaacauuugugguggc ---------------------------------------------------------------------GUAAGGCACCCUUCUGAGUAGA--------------------------------- 2 -1,0 >hsa-mir-508 5p:26-48;3p:61-83 Tumor ccaccuucagcugaguguagugcccUACUCCAGAGGGCGUCACUCAUGuaaacuaaaacaUGAUUGUAGCCUUUUGGAGUAGAguaauacacaucacguaacgcauauuuggugg ------------------------------------------------------------UGAUUGUAGCCUUUUGGAGUAGA-------------------------------- 2 0,0 --------------------------------------------------------------AUUGUAGCCUUUUGGAGUAGA-------------------------------- 2 2,0 >hsa-mir-509-1 5p:20-40;3p:55-76 Tumor caugcugugugugguacccUACUGCAGACAGUGGCAAUCAuguauaauuaaaaaUGAUUGGUACGUCUGUGGGUAGaguacugcaugacacaug ------------------------------------------------------UGAUUGGUACGUCUGUGGGUAGu----------------- 2 0,0 ------------------------------------------------------UGAUUGGUACGUCUGUGGGUAGA----------------- 2 0,1 >hsa-mir-509-2 5p:20-40;3p:55-76 Tumor caugcugugugugguacccUACUGCAGACAGUGGCAAUCAuguauaauuaaaaaUGAUUGGUACGUCUGUGGGUAGaguacugcaugacac ------------------------------------------------------UGAUUGGUACGUCUGUGGGUAGu-------------- 2 0,0 ------------------------------------------------------UGAUUGGUACGUCUGUGGGUAGA-------------- 2 0,1 >hsa-mir-509-3 5p:10-31;3p:44-65 Tumor gugguacccUACUGCAGACGUGGCAAUCAUGuauaauuaaaaaUGAUUGGUACGUCUGUGGGUAGaguacugcau -------------------------------------------UGAUUGGUACGUCUGUGGGUAGu--------- 2 0,0 -------------------------------------------UGAUUGGUACGUCUGUGGGUAGA--------- 2 0,1 >hsa-mir-5095 5pM:7-27 Tumor cugggaUUACAGGCGUGAACCACCGCGcccggccuaacuuuuaagaaacgucggcccgggagcgguggcucacgccuguaaucccagc ---------------------------------------------------------------GGUGGCUCACGCCUGUAAUCCCAGC 2 ----------------------------------------------------------------GUGGCUCACGCCUGUAAUC----- 2 ----------------------------------------------------------------GUGGCUCACGCCUGUAAUCCC--- 4 ----------------------------------------------------------------GUGGCUCACGCCUGUAAUCCCAGC 2 -----------------------------------------------------------------UGGCUCACGCCUGUAAUCC---- 2 -----------------------------------------------------------------UGGCUCACGCCUGUAAUCCC--- 3 -----------------------------------------------------------------UGGCUCACGCCUGUAAUCCCAG- 2 -----------------------------------------------------------------UGGCUCACGCCUGUAAUCCCAGC 2 -------------------------------------------------------------------GCUCACGCCUGUAAUCCCAGC 4 --------------------------------------------------------------------CUCACGCCUGUAAUCCCAGC 11 >hsa-mir-5096 5pM:13-33 Tumor aguagaggugggGUUUCACCAUGUUGGUCAGGCuggucucaaacuccugaccucaggugauccauccacc --------------------------------CUGGUCUCAAACUCCUGACCU----------------- 2 -----------------------------------------AACUCCUGACCUCAGGUGAUC-------- 2 -----------------------------------------AACUCCUGACCUCAGGUGAUCC------- 2 ------------------------------------------ACUCCUGACCUCAGGUGAUCC------- 2 -------------------------------------------CUCCUGACCUCAGGUGAUCCA------ 2 ----------------------------------------------CUGACCUCAGGUGAUCCA------ 2 >hsa-mir-511-1 5pM:16-36 Tumor caauagacacccaucGUGUCUUUUGCUCUGCAGUCAguaaauauuuuuuugugaauguguagcaaaagacagaauggugguccauug --------------CGUGUCUUUUGCUCUGCAGUCA--------------------------------------------------- 9 -1,0 ---------------GUGUCUUUUGCUCUGCAGUC---------------------------------------------------- 4 0,-1 ---------------GUGUCUUUUGCUCUGCAGUCA--------------------------------------------------- 195 0,0 ---------------GUGUCUUUUGCUCUGCAGUCAa-------------------------------------------------- 2 0,0 ---------------GUGUCUUUUGCUCUGCAGUCAG-------------------------------------------------- 12 0,1 ---------------GUGUCUUUUGCUCUGCAGUCAGU------------------------------------------------- 4 0,2 -----------------------------------------------------AAUGUGUAGCAAAAGACAG--------------- 4 -----------------------------------------------------AAUGUGUAGCAAAAGACAGA-------------- 369 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAuu------------ 2 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAA------------- 316 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAAa------------ 128 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAAg------------ 2 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAAU------------ 379 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAAUu----------- 4 ------------------------------------------------------AUGUGUAGCAAAAGACAGA-------------- 2 ------------------------------------------------------AUGUGUAGCAAAAGACAGAAU------------ 2 --------------------------------------------------------GUGUAGCAAAAGACAGAA------------- 5 --------------------------------------------------------GUGUAGCAAAAGACAGAAU------------ 4 >hsa-mir-511-2 5pM:16-36 Tumor caauagacacccaucGUGUCUUUUGCUCUGCAGUCAguaaauauuuuuuugugaauguguagcaaaagacagaauggugguccauug --------------CGUGUCUUUUGCUCUGCAGUCA--------------------------------------------------- 9 -1,0 ---------------GUGUCUUUUGCUCUGCAGUC---------------------------------------------------- 4 0,-1 ---------------GUGUCUUUUGCUCUGCAGUCA--------------------------------------------------- 195 0,0 ---------------GUGUCUUUUGCUCUGCAGUCAa-------------------------------------------------- 2 0,0 ---------------GUGUCUUUUGCUCUGCAGUCAG-------------------------------------------------- 12 0,1 ---------------GUGUCUUUUGCUCUGCAGUCAGU------------------------------------------------- 4 0,2 -----------------------------------------------------AAUGUGUAGCAAAAGACAG--------------- 4 -----------------------------------------------------AAUGUGUAGCAAAAGACAGA-------------- 369 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAuu------------ 2 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAA------------- 316 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAAa------------ 128 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAAg------------ 2 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAAU------------ 379 -----------------------------------------------------AAUGUGUAGCAAAAGACAGAAUu----------- 4 ------------------------------------------------------AUGUGUAGCAAAAGACAGA-------------- 2 ------------------------------------------------------AUGUGUAGCAAAAGACAGAAU------------ 2 --------------------------------------------------------GUGUAGCAAAAGACAGAA------------- 5 --------------------------------------------------------GUGUAGCAAAAGACAGAAU------------ 4 >hsa-mir-512-1 5p:14-36;3p:51-72 Tumor ucucagucuguggCACUCAGCCUUGAGGGCACUUUCuggugccagaaugaAAGUGCUGUCAUAGCUGAGGUCcaaugacugagg --------------------------------------------------AAGUGCUGUCAUAGCUGAGG-------------- 2 0,-2 --------------------------------------------------AAGUGCUGUCAUAGCUGAGGU------------- 9 0,-1 --------------------------------------------------AAGUGCUGUCAUAGCUGAGGUa------------ 2 0,-1 --------------------------------------------------AAGUGCUGUCAUAGCUGAGGUC------------ 2 0,0 --------------------------------------------------AAGUGCUGUCAUAGCUGAGGUCa----------- 2 0,0 --------------------------------------------------AAGUGCUGUCAUAGCUGAGGUCg----------- 2 0,0 --------------------------------------------------AAGUGCUGUCAUAGCUGAGGUCu----------- 7 0,0 >hsa-mir-512-2 5p:20-42;3p:57-78 Tumor gguacuucucagucuguggCACUCAGCCUUGAGGGCACUUUCuggugccagaaugaAAGUGCUGUCAUAGCUGAGGUCcaaugacugaggcgagcacc --------------------------------------------------------AAGUGCUGUCAUAGCUGAGG---------------------- 2 0,-2 --------------------------------------------------------AAGUGCUGUCAUAGCUGAGGU--------------------- 9 0,-1 --------------------------------------------------------AAGUGCUGUCAUAGCUGAGGUa-------------------- 2 0,-1 --------------------------------------------------------AAGUGCUGUCAUAGCUGAGGUC-------------------- 2 0,0 --------------------------------------------------------AAGUGCUGUCAUAGCUGAGGUCa------------------- 2 0,0 --------------------------------------------------------AAGUGCUGUCAUAGCUGAGGUCg------------------- 2 0,0 --------------------------------------------------------AAGUGCUGUCAUAGCUGAGGUCu------------------- 7 0,0 >hsa-mir-513a-1 5p:37-54;3p:72-94 Tumor gggaugccacauucagccauucagcguacagugccuUUCACAGGGAGGUGUCAUuuaugugaacuaaaauaUAAAUUUCACCUUUCUGAGAAGGguaauguacagcaugcacugcauaugugguguccc -----------------------------------------------------------------------UAAAUUUCACCUUUCUGAGA-------------------------------------- 2 0,-3 >hsa-mir-513a-2 5p:36-53;3p:71-93 Tumor ggaugccacauucagccauucagugugcagugccuUUCACAGGGAGGUGUCAUuuaugugaacuaaaauaUAAAUUUCACCUUUCUGAGAAGGguaauguacagcaugcacugcauauguggugucc ----------------------------------------------------------------------UAAAUUUCACCUUUCUGAGA------------------------------------- 2 0,-3 >hsa-mir-513c 5pM:14-35 Tumor gcguacagugccuUUCUCAAGGAGGUGUCGUUUAUgugaacuaaaauauaaauuucaccuuucugagaagaguaauguacagca ------------------------------------------------UAAAUUUCACCUUUCUGAGA---------------- 2 -------------------------------------------------AAAUUUCACCUUUCUGAGAAGA------------- 2 >hsa-mir-514-1 3pM:59-79 Tumor aacauguugucugugguacccuacucuggagagugacaaucauguauaauuaaauuugAUUGACACUUCUGUGAGUAGAguaacgcaugacacguacg ---------------------UACUCUGGAGAGUGACAAUCA-------------------------------------------------------- 2 --------------------------------------------------------UGAUUGACACUUCUGUGAGUAG-------------------- 3 -2,-1 --------------------------------------------------------UGAUUGACACUUCUGUGAGUAGA------------------- 4 -2,0 ----------------------------------------------------------AUUGACACUUCUGUGAGUAG-------------------- 6 0,-1 ----------------------------------------------------------AUUGACACUUCUGUGAGUAGu------------------- 2 0,-1 ----------------------------------------------------------AUUGACACUUCUGUGAGUAGA------------------- 58 0,0 ----------------------------------------------------------AUUGACACUUCUGUGAGUAGAa------------------ 2 0,0 >hsa-mir-514-2 3pM:54-74 Tumor guugucugugguacccuacucuggagagugacaaucauguauaacuaaauuugAUUGACACUUCUGUGAGUAGAguaacgcaugacac ----------------UACUCUGGAGAGUGACAAUCA--------------------------------------------------- 2 ---------------------------------------------------UGAUUGACACUUCUGUGAGUAG--------------- 3 -2,-1 ---------------------------------------------------UGAUUGACACUUCUGUGAGUAGA-------------- 4 -2,0 -----------------------------------------------------AUUGACACUUCUGUGAGUAG--------------- 6 0,-1 -----------------------------------------------------AUUGACACUUCUGUGAGUAGu-------------- 2 0,-1 -----------------------------------------------------AUUGACACUUCUGUGAGUAGA-------------- 58 0,0 -----------------------------------------------------AUUGACACUUCUGUGAGUAGAa------------- 2 0,0 >hsa-mir-514-3 3pM:54-74 Tumor guugucugugguacccuacucuggagagugacaaucauguauaacuaaauuugAUUGACACUUCUGUGAGUAGAguaacgcaugacac ----------------UACUCUGGAGAGUGACAAUCA--------------------------------------------------- 2 ---------------------------------------------------UGAUUGACACUUCUGUGAGUAG--------------- 3 -2,-1 ---------------------------------------------------UGAUUGACACUUCUGUGAGUAGA-------------- 4 -2,0 -----------------------------------------------------AUUGACACUUCUGUGAGUAG--------------- 6 0,-1 -----------------------------------------------------AUUGACACUUCUGUGAGUAGu-------------- 2 0,-1 -----------------------------------------------------AUUGACACUUCUGUGAGUAGA-------------- 58 0,0 -----------------------------------------------------AUUGACACUUCUGUGAGUAGAa------------- 2 0,0 >hsa-mir-515-1 5p:14-37;3p:51-72 Tumor ucucaugcagucaUUCUCCAAAAGAAAGCACUUUCUGuugucugaaagcaGAGUGCCUUCUUUUGGAGCGUUacuguuugaga -------------UUCUCCAAAAGAAAGCACUUU------------------------------------------------- 2 0,-3 -------------UUCUCCAAAAGAAAGCACUUUC------------------------------------------------ 3 0,-2 -------------UUCUCCAAAAGAAAGCACUUUCU----------------------------------------------- 5 0,-1 --------------------------------------------------GAGUGCCUUCUUUUGGAGCGUU----------- 8 0,0 >hsa-mir-515-2 5p:14-37;3p:51-72 Tumor ucucaugcagucaUUCUCCAAAAGAAAGCACUUUCUGuugucugaaagcaGAGUGCCUUCUUUUGGAGCGUUacuguuugaga -------------UUCUCCAAAAGAAAGCACUUU------------------------------------------------- 2 0,-3 -------------UUCUCCAAAAGAAAGCACUUUC------------------------------------------------ 3 0,-2 -------------UUCUCCAAAAGAAAGCACUUUCU----------------------------------------------- 5 0,-1 --------------------------------------------------GAGUGCCUUCUUUUGGAGCGUU----------- 8 0,0 >hsa-mir-516a-1 5p:16-38;3p:61-78 Tumor ucucaggcugugaccUUCUCGAGGAAAGAAGCACUUUCuguugucugaaagaaaagaaagUGCUUCCUUUCAGAGGGUuacgguuugaga ---------------UUCUCGAGGAAAGAAGCA--------------------------------------------------------- 12 0,-5 ---------------UUCUCGAGGAAAGAAGCAC-------------------------------------------------------- 11 0,-4 ---------------UUCUCGAGGAAAGAAGCACU------------------------------------------------------- 34 0,-3 ---------------UUCUCGAGGAAAGAAGCACUau----------------------------------------------------- 2 0,-3 ---------------UUCUCGAGGAAAGAAGCACUU------------------------------------------------------ 84 0,-2 ---------------UUCUCGAGGAAAGAAGCACUUa----------------------------------------------------- 5 0,-2 ---------------UUCUCGAGGAAAGAAGCACUUU----------------------------------------------------- 654 0,-1 ---------------UUCUCGAGGAAAGAAGCACUUUa---------------------------------------------------- 2 0,-1 ---------------UUCUCGAGGAAAGAAGCACUUUau--------------------------------------------------- 4 0,-1 ---------------UUCUCGAGGAAAGAAGCACUUUu---------------------------------------------------- 29 0,-1 ---------------UUCUCGAGGAAAGAAGCACUUUuu--------------------------------------------------- 2 0,-1 ---------------UUCUCGAGGAAAGAAGCACUUUC---------------------------------------------------- 317 0,0 ---------------UUCUCGAGGAAAGAAGCACUUUCa--------------------------------------------------- 4 0,0 ---------------UUCUCGAGGAAAGAAGCACUUUCU--------------------------------------------------- 342 0,1 ----------------UCUCGAGGAAAGAAGCACUUU----------------------------------------------------- 10 1,-1 ----------------UCUCGAGGAAAGAAGCACUUUCU--------------------------------------------------- 3 1,1 >hsa-mir-516a-2 5p:16-38;3p:61-78 Tumor ucucagguugugaccUUCUCGAGGAAAGAAGCACUUUCuguugucugaaagaaaagaaagUGCUUCCUUUCAGAGGGUuacgguuugaga ---------------UUCUCGAGGAAAGAAGCA--------------------------------------------------------- 12 0,-5 ---------------UUCUCGAGGAAAGAAGCAC-------------------------------------------------------- 11 0,-4 ---------------UUCUCGAGGAAAGAAGCACU------------------------------------------------------- 34 0,-3 ---------------UUCUCGAGGAAAGAAGCACUau----------------------------------------------------- 2 0,-3 ---------------UUCUCGAGGAAAGAAGCACUU------------------------------------------------------ 84 0,-2 ---------------UUCUCGAGGAAAGAAGCACUUa----------------------------------------------------- 5 0,-2 ---------------UUCUCGAGGAAAGAAGCACUUU----------------------------------------------------- 654 0,-1 ---------------UUCUCGAGGAAAGAAGCACUUUa---------------------------------------------------- 2 0,-1 ---------------UUCUCGAGGAAAGAAGCACUUUau--------------------------------------------------- 4 0,-1 ---------------UUCUCGAGGAAAGAAGCACUUUu---------------------------------------------------- 29 0,-1 ---------------UUCUCGAGGAAAGAAGCACUUUuu--------------------------------------------------- 2 0,-1 ---------------UUCUCGAGGAAAGAAGCACUUUC---------------------------------------------------- 317 0,0 ---------------UUCUCGAGGAAAGAAGCACUUUCa--------------------------------------------------- 4 0,0 ---------------UUCUCGAGGAAAGAAGCACUUUCU--------------------------------------------------- 342 0,1 ----------------UCUCGAGGAAAGAAGCACUUU----------------------------------------------------- 10 1,-1 ----------------UCUCGAGGAAAGAAGCACUUUCU--------------------------------------------------- 3 1,1 >hsa-mir-516b-1 MA:16-37;mi:61-78 Tumor ucucaggcugugaccAUCUGGAGGUAAGAAGCACUUUcuguuuugugaaagaaaagaaagUGCUUCCUUUCAGAGGGUuacucuuugaga ---------------AUCUGGAGGUAAGAAGCACUUU----------------------------------------------------- 6 0,0 >hsa-mir-516b-2 MA:16-37;mi:56-73 Tumor ucucaugaugugaccAUCUGGAGGUAAGAAGCACUUUguguuuugugaaagaaagUGCUUCCUUUCAGAGGGUuacucuuugaga ---------------AUCUGGAGGUAAGAAGCACUUU------------------------------------------------ 6 0,0 >hsa-mir-517a mi:15-36;MA:54-75 Tumor ucucaggcagugacCCUCUAGAUGGAAGCACUGUCUguuguauaaaagaaaagAUCGUGCAUCCCUUUAGAGUGUuacuguuugaga -----------------------------------------------------AUCGUGCAUCCCUUUAGAGU-------------- 2 0,-2 -----------------------------------------------------AUCGUGCAUCCCUUUAGAGUGU------------ 26 0,0 >hsa-mir-517b mi:6-27;MA:44-65 Tumor gugacCCUCUAGAUGGAAGCACUGUCUguugucuaagaaaagaUCGUGCAUCCCUUUAGAGUGUUac ------------------------------------------AUCGUGCAUCCCUUUAGAGU----- 2 -1,-3 ------------------------------------------AUCGUGCAUCCCUUUAGAGUGU--- 26 -1,-1 >hsa-mir-517c mi:20-41;MA:57-78 Tumor gaagaucucaggcagugacCCUCUAGAUGGAAGCACUGUCUguugucuaagaaaagAUCGUGCAUCCUUUUAGAGUGUuacuguuugagaaaauc --------------------------------------------------------AUCGUGCAUCCUUUUAGAGUGU----------------- 6 0,0 >hsa-mir-518a-1 5p:14-33;3p:51-72 Tumor ucucaagcugugaCUGCAAAGGGAAGCCCUUUCuguugucugaaagaagaGAAAGCGCUUCCCUUUGCUGGAuuacgguuugaga -------------CUGCAAAGGGAAGCCCUUU----------------------------------------------------- 5 0,-1 -------------CUGCAAAGGGAAGCCCUUUau--------------------------------------------------- 2 0,-1 -------------CUGCAAAGGGAAGCCCUUUu---------------------------------------------------- 3 0,-1 -------------CUGCAAAGGGAAGCCCUUUC---------------------------------------------------- 5 0,0 -------------CUGCAAAGGGAAGCCCUUUCa--------------------------------------------------- 2 0,0 -------------CUGCAAAGGGAAGCCCUUUCU--------------------------------------------------- 39 0,1 ---------------------------------------------------AAAGCGCUUCCCUUUGCUGGAU------------ 2 1,1 >hsa-mir-518a-2 5p:16-35;3p:53-74 Tumor ucucaagcuguggguCUGCAAAGGGAAGCCCUUUCuguugucuaaaagaagaGAAAGCGCUUCCCUUUGCUGGAuuacgguuugaga ---------------CUGCAAAGGGAAGCCCUUU----------------------------------------------------- 5 0,-1 ---------------CUGCAAAGGGAAGCCCUUUau--------------------------------------------------- 2 0,-1 ---------------CUGCAAAGGGAAGCCCUUUu---------------------------------------------------- 3 0,-1 ---------------CUGCAAAGGGAAGCCCUUUC---------------------------------------------------- 5 0,0 ---------------CUGCAAAGGGAAGCCCUUUCa--------------------------------------------------- 2 0,0 ---------------CUGCAAAGGGAAGCCCUUUCU--------------------------------------------------- 39 0,1 -----------------------------------------------------AAAGCGCUUCCCUUUGCUGGAU------------ 2 1,1 >hsa-mir-518b 3pM:51-72 Tumor ucaugcuguggcccuccagagggaagcgcuuucuguugucugaaagaaaaCAAAGCGCUCCCCUUUAGAGGUuuacgguuuga --------------------------------------------------CAAAGCGCUCCCCUUUAGAGGU----------- 4 0,0 >hsa-mir-518c mi:24-46;MA:62-84 Tumor gcgagaagaucucaugcugugacUCUCUGGAGGGAAGCACUUUCUGuugucugaaagaaaaCAAAGCGCUUCUCUUUAGAGUGUuacgguuugagaaaagc -------------------------------------------------------------CAAAGCGCUUCUCUUUAGAGUGa----------------- 2 0,-1 -------------------------------------------------------------CAAAGCGCUUCUCUUUAGAGUGU----------------- 6 0,0 >hsa-mir-518e mi:16-37;MA:54-74 Tumor ucucaggcugugaccCUCUAGAGGGAAGCGCUUUCUGuuggcuaaaagaaaagAAAGCGCUUCCCUUCAGAGUGuuaacgcuuugaga ---------------CUCUAGAGGGAAGCGCUUU------------------------------------------------------ 3 0,-3 ---------------CUCUAGAGGGAAGCGCUUUC----------------------------------------------------- 2 0,-2 ---------------CUCUAGAGGGAAGCGCUUUCU---------------------------------------------------- 16 0,-1 -----------------------------------------------------AAAGCGCUUCCCUUCAGAGUGU------------- 5 0,1 ------------------------------------------------------AAGCGCUUCCCUUCAGAGUGa------------- 2 1,0 >hsa-mir-518f mi:16-37;MA:53-73 Tumor ucucaugcugugaccCUCUAGAGGGAAGCACUUUCUCuugucuaaaagaaaaGAAAGCGCUUCUCUUUAGAGGauuacucuuugaga ----------------------------------------------------GAAAGCGCUUCUCUUUAGAGGA------------- 2 0,1 >hsa-mir-519a-1 mi:15-36;MA:53-74 Tumor cucaggcugugacaCUCUAGAGGGAAGCGCUUUCUGuugucugaaagaaaggAAAGUGCAUCCUUUUAGAGUGUuacuguuugag -------------ACUCUAGAGGGAAGCGCUUU---------------------------------------------------- 4 -1,-3 -------------ACUCUAGAGGGAAGCGCUUUC--------------------------------------------------- 6 -1,-2 -------------ACUCUAGAGGGAAGCGCUUUCU-------------------------------------------------- 33 -1,-1 --------------CUCUAGAGGGAAGCGCUUU---------------------------------------------------- 3 0,-3 --------------CUCUAGAGGGAAGCGCUUUC--------------------------------------------------- 2 0,-2 --------------CUCUAGAGGGAAGCGCUUUCU-------------------------------------------------- 16 0,-1 ----------------------------------------------------AAAGUGCAUCCUUUUAGA--------------- 7 0,-4 ----------------------------------------------------AAAGUGCAUCCUUUUAGAG-------------- 6 0,-3 ----------------------------------------------------AAAGUGCAUCCUUUUAGAGU------------- 5 0,-2 ----------------------------------------------------AAAGUGCAUCCUUUUAGAGUuu----------- 4 0,-2 ----------------------------------------------------AAAGUGCAUCCUUUUAGAGUG------------ 11 0,-1 ----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGa----------- 8 0,-1 ----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGc----------- 2 0,-1 ----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGg----------- 4 0,-1 ----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGU----------- 1389 0,0 ----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGUa---------- 6 0,0 ----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGUU---------- 6 0,1 ----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGUUu--------- 2 0,1 -----------------------------------------------------AAGUGCAUCCUUUUAGAGUGU----------- 39 1,0 -----------------------------------------------------AAGUGCAUCCUUUUAGAGUGUU---------- 4 1,1 >hsa-mir-519a-2 3pM:54-75 Tumor ucucaggcugugucccucuacagggaagcgcuuucuguugucugaaagaaaggAAAGUGCAUCCUUUUAGAGUGUuacuguuugaga --------------CCUCUACAGGGAAGCGCUUU----------------------------------------------------- 2 --------------CCUCUACAGGGAAGCGCUUUCU--------------------------------------------------- 56 ---------------CUCUACAGGGAAGCGCUUUCU--------------------------------------------------- 2 -----------------------------------------------------AAAGUGCAUCCUUUUAGA---------------- 7 0,-4 -----------------------------------------------------AAAGUGCAUCCUUUUAGAG--------------- 6 0,-3 -----------------------------------------------------AAAGUGCAUCCUUUUAGAGU-------------- 5 0,-2 -----------------------------------------------------AAAGUGCAUCCUUUUAGAGUuu------------ 4 0,-2 -----------------------------------------------------AAAGUGCAUCCUUUUAGAGUG------------- 11 0,-1 -----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGa------------ 8 0,-1 -----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGc------------ 2 0,-1 -----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGg------------ 4 0,-1 -----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGU------------ 1389 0,0 -----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGUa----------- 6 0,0 -----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGUU----------- 6 0,1 -----------------------------------------------------AAAGUGCAUCCUUUUAGAGUGUUu---------- 2 0,1 ------------------------------------------------------AAGUGCAUCCUUUUAGAGUGU------------ 39 1,0 ------------------------------------------------------AAGUGCAUCCUUUUAGAGUGUU----------- 4 1,1 >hsa-mir-519b 5p:13-34;3p:51-72 Tumor caugcugugaccCUCUAGAGGGAAGCGCUUUCUGuugucugaaagaaaagAAAGUGCAUCCUUUUAGAGGUUuacuguuug ------------CUCUAGAGGGAAGCGCUUU-------------------------------------------------- 3 0,-3 ------------CUCUAGAGGGAAGCGCUUUC------------------------------------------------- 2 0,-2 ------------CUCUAGAGGGAAGCGCUUUCU------------------------------------------------ 16 0,-1 --------------------------------------------------AAAGUGCAUCCUUUUAGA------------- 7 0,-4 --------------------------------------------------AAAGUGCAUCCUUUUAGAG------------ 6 0,-3 --------------------------------------------------AAAGUGCAUCCUUUUAGAGG----------- 8 0,-2 --------------------------------------------------AAAGUGCAUCCUUUUAGAGGUU--------- 5 0,0 >hsa-mir-519c 5p:16-37;3p:54-75 Tumor ucucagccugugaccCUCUAGAGGGAAGCGCUUUCUGuugucugaaagaaaagAAAGUGCAUCUUUUUAGAGGAUuacaguuugaga ---------------CUCUAGAGGGAAGCGCUUU----------------------------------------------------- 3 0,-3 ---------------CUCUAGAGGGAAGCGCUUUC---------------------------------------------------- 2 0,-2 ---------------CUCUAGAGGGAAGCGCUUUCU--------------------------------------------------- 16 0,-1 -----------------------------------------------------AAAGUGCAUCUUUUUAGAGGAU------------ 4 0,0 >hsa-mir-519d 3pM:54-75 Tumor ucccaugcugugacccuccaaagggaagcgcuuucuguuuguuuucucuuaaaCAAAGUGCCUCCCUUUAGAGUGuuaccguuuggga -----------------------------------------------------CAAAGUGCCUCCCUUUAGAGUGU------------ 4 0,1 >hsa-mir-519e mi:14-35;MA:52-73 Tumor ucucaugcagucaUUCUCCAAAAGGGAGCACUUUCuguuugaaagaaaacaAAGUGCCUCCUUUUAGAGUGUUacuguuugaga --------------------------------------------------AAAGUGCCUCCUUUUAGAGUGU------------ 7 -1,-1 >hsa-mir-520b 3pM:41-61 Tumor cccucuacagggaagcgcuuucuguugucugaaagaaaagAAAGUGCUUCCUUUUAGAGGG -CCUCUACAGGGAAGCGCUUU---------------------------------------- 2 -CCUCUACAGGGAAGCGCUUUCU-------------------------------------- 56 --CUCUACAGGGAAGCGCUUUCU-------------------------------------- 2 >hsa-mir-520f 3pM:55-76 Tumor ucucaggcugugacccucuaaagggaagcgcuuucuguggucagaaagaaaagcAAGUGCUUCCUUUUAGAGGGUUaccguuuggga -----------------------------------------------------CAAGUGCUUCCUUUUAGAGGGU------------ 8 -1,-1 >hsa-mir-520g 3pM:55-78 Tumor ucccaugcugugacccucuagaggaagcacuuucuguuuguugucugagaaaaaACAAAGUGCUUCCCUUUAGAGUGUuaccguuuggga ------------------------------------------------------ACAAAGUGCUUCCCUUUAGAGU-------------- 2 0,-2 ------------------------------------------------------ACAAAGUGCUUCCCUUUAGAGUG------------- 2 0,-1 >hsa-mir-520h 3pM:55-76 Tumor ucccaugcugugacccucuagaggaagcacuuucuguuuguugucugagaaaaaACAAAGUGCUUCCCUUUAGAGUuacuguuuggga ------------------------------------------------------ACAAAGUGCUUCCCUUUAGAGU------------ 2 0,0 >hsa-mir-521-1 3pM:54-75 Tumor ucucaggcugugacccuccaaagggaagaacuuucuguugucuaaaagaaaagAACGCACUUCCCUUUAGAGUGUuaccgugugaga --------------CCUCCAAAGGGAAGAACUUUCU--------------------------------------------------- 6 -----------------------------------------------------AACGCACUUCCCUUUAGA---------------- 2 0,-4 -----------------------------------------------------AACGCACUUCCCUUUAGAG--------------- 2 0,-3 -----------------------------------------------------AACGCACUUCCCUUUAGAGU-------------- 5 0,-2 -----------------------------------------------------AACGCACUUCCCUUUAGAGUG------------- 4 0,-1 -----------------------------------------------------AACGCACUUCCCUUUAGAGUGa------------ 2 0,-1 -----------------------------------------------------AACGCACUUCCCUUUAGAGUGc------------ 2 0,-1 -----------------------------------------------------AACGCACUUCCCUUUAGAGUGU------------ 275 0,0 ------------------------------------------------------ACGCACUUCCCUUUAGAGUGU------------ 3 1,0 >hsa-mir-521-2 3pM:54-75 Tumor ucucgggcugugacucuccaaagggaagaauuuucucuugucuaaaagaaaagAACGCACUUCCCUUUAGAGUGUuaccgugugaga -----------------------------------------------------AACGCACUUCCCUUUAGA---------------- 2 0,-4 -----------------------------------------------------AACGCACUUCCCUUUAGAG--------------- 2 0,-3 -----------------------------------------------------AACGCACUUCCCUUUAGAGU-------------- 5 0,-2 -----------------------------------------------------AACGCACUUCCCUUUAGAGUG------------- 4 0,-1 -----------------------------------------------------AACGCACUUCCCUUUAGAGUGa------------ 2 0,-1 -----------------------------------------------------AACGCACUUCCCUUUAGAGUGc------------ 2 0,-1 -----------------------------------------------------AACGCACUUCCCUUUAGAGUGU------------ 275 0,0 ------------------------------------------------------ACGCACUUCCCUUUAGAGUGU------------ 3 1,0 >hsa-mir-522 mi:16-37;MA:54-75 Tumor ucucaggcuguguccCUCUAGAGGGAAGCGCUUUCUGuugucugaaagaaaagAAAAUGGUUCCCUUUAGAGUGUuacgcuuugaga ---------------CUCUAGAGGGAAGCGCUUU----------------------------------------------------- 3 0,-3 ---------------CUCUAGAGGGAAGCGCUUUC---------------------------------------------------- 2 0,-2 ---------------CUCUAGAGGGAAGCGCUUUCU--------------------------------------------------- 16 0,-1 -----------------------------------------------------AAAAUGGUUCCCUUUAGAG--------------- 2 0,-3 -----------------------------------------------------AAAAUGGUUCCCUUUAGAGa-------------- 3 0,-3 -----------------------------------------------------AAAAUGGUUCCCUUUAGAGU-------------- 22 0,-2 -----------------------------------------------------AAAAUGGUUCCCUUUAGAGUG------------- 32 0,-1 -----------------------------------------------------AAAAUGGUUCCCUUUAGAGUGa------------ 37 0,-1 -----------------------------------------------------AAAAUGGUUCCCUUUAGAGUGaa----------- 2 0,-1 -----------------------------------------------------AAAAUGGUUCCCUUUAGAGUGU------------ 110 0,0 -----------------------------------------------------AAAAUGGUUCCCUUUAGAGUGUU----------- 3 0,1 >hsa-mir-523 mi:16-37;MA:53-75 Tumor ucucaugcugugaccCUCUAGAGGGAAGCGCUUUCUGuugucugaaagaaaaGAACGCGCUUCCCUAUAGAGGGUuacccuuugaga ---------------CUCUAGAGGGAAGCGCUUU----------------------------------------------------- 3 0,-3 ---------------CUCUAGAGGGAAGCGCUUUC---------------------------------------------------- 2 0,-2 ---------------CUCUAGAGGGAAGCGCUUUCU--------------------------------------------------- 16 0,-1 >hsa-mir-524 5p:16-37;3p:53-73 Tumor ucucaugcugugaccCUACAAAGGGAAGCACUUUCUCuuguccaaaggaaaaGAAGGCGCUUCCCUUUGGAGUguuacgguuugaga ---------------CUACAAAGGGAAGCACUUU----------------------------------------------------- 2 0,-3 ---------------CUACAAAGGGAAGCACUUUCU--------------------------------------------------- 2 0,-1 ---------------CUACAAAGGGAAGCACUUUCUa-------------------------------------------------- 2 0,-1 ---------------CUACAAAGGGAAGCACUUUCUC-------------------------------------------------- 2 0,0 >hsa-mir-525 5p:15-35;3p:52-73 Tumor cucaagcugugacuCUCCAGAGGGAUGCACUUUCUcuuaugugaaaaaaaaGAAGGCGCUUCCCUUUAGAGCGuuacgguuuggg ----------------------------------------------------AAGGCGCUUCCCUUUAGAGCGU----------- 2 1,1 >hsa-mir-526b MA:14-36;mi:51-72 Tumor ucaggcugugaccCUCUUGAGGGAAGCACUUUCUGUugucugaaagaagaGAAAGUGCUUCCUUUUAGAGGCuuacugucuga -------------CUCUUGAGGGAAGCACUUUCU------------------------------------------------- 2 0,-2 -------------CUCUUGAGGGAAGCACUUUCUGU----------------------------------------------- 2 0,0 >hsa-mir-527 5pM:14-33 Tumor ucucaagcugugaCUGCAAAGGGAAGCCCUUUCuguugucuaaaagaaaagaaagugcuucccuuuggugaauuacgguuugaga -------------CUGCAAAGGGAAGCCCUUU----------------------------------------------------- 5 0,-1 -------------CUGCAAAGGGAAGCCCUUUau--------------------------------------------------- 2 0,-1 -------------CUGCAAAGGGAAGCCCUUUu---------------------------------------------------- 3 0,-1 -------------CUGCAAAGGGAAGCCCUUUC---------------------------------------------------- 5 0,0 -------------CUGCAAAGGGAAGCCCUUUCa--------------------------------------------------- 2 0,0 -------------CUGCAAAGGGAAGCCCUUUCU--------------------------------------------------- 39 0,1 ---------------------------------------------------AAAGUGCUUCCCUUUGGUGAAa------------ 2 ---------------------------------------------------AAAGUGCUUCCCUUUGGUGAAU------------ 3 ---------------------------------------------------AAAGUGCUUCCCUUUGGUGAAUU----------- 2 >hsa-mir-532 5p:20-41;3p:57-78 Tumor cgacuugcuuucucuccucCAUGCCUUGAGUGUAGGACCGUuggcaucuuaauuacCCUCCCACACCCAAGGCUUGCAaaaaagcgagccu -------------------CAUGCCUUGAGUGUAGGA------------------------------------------------------ 32 0,-4 -------------------CAUGCCUUGAGUGUAGGAa----------------------------------------------------- 2 0,-4 -------------------CAUGCCUUGAGUGUAGGAaa---------------------------------------------------- 9 0,-4 -------------------CAUGCCUUGAGUGUAGGAC----------------------------------------------------- 59 0,-3 -------------------CAUGCCUUGAGUGUAGGACa---------------------------------------------------- 62 0,-3 -------------------CAUGCCUUGAGUGUAGGACu---------------------------------------------------- 8 0,-3 -------------------CAUGCCUUGAGUGUAGGACC---------------------------------------------------- 165 0,-2 -------------------CAUGCCUUGAGUGUAGGACCa--------------------------------------------------- 4 0,-2 -------------------CAUGCCUUGAGUGUAGGACCau-------------------------------------------------- 8 0,-2 -------------------CAUGCCUUGAGUGUAGGACCuu-------------------------------------------------- 2 0,-2 -------------------CAUGCCUUGAGUGUAGGACCG--------------------------------------------------- 463 0,-1 -------------------CAUGCCUUGAGUGUAGGACCGa-------------------------------------------------- 196 0,-1 -------------------CAUGCCUUGAGUGUAGGACCGau------------------------------------------------- 2 0,-1 -------------------CAUGCCUUGAGUGUAGGACCGc-------------------------------------------------- 4 0,-1 -------------------CAUGCCUUGAGUGUAGGACCGU-------------------------------------------------- 5334 0,0 -------------------CAUGCCUUGAGUGUAGGACCGUa------------------------------------------------- 374 0,0 -------------------CAUGCCUUGAGUGUAGGACCGUaa------------------------------------------------ 37 0,0 -------------------CAUGCCUUGAGUGUAGGACCGUau------------------------------------------------ 24 0,0 -------------------CAUGCCUUGAGUGUAGGACCGUc------------------------------------------------- 2 0,0 -------------------CAUGCCUUGAGUGUAGGACCGUg------------------------------------------------- 2 0,0 -------------------CAUGCCUUGAGUGUAGGACCGUU------------------------------------------------- 469 0,1 -------------------CAUGCCUUGAGUGUAGGACCGUUa------------------------------------------------ 2 0,1 -------------------CAUGCCUUGAGUGUAGGACCGUUu------------------------------------------------ 18 0,1 --------------------AUGCCUUGAGUGUAGGACa---------------------------------------------------- 2 1,-3 --------------------AUGCCUUGAGUGUAGGACC---------------------------------------------------- 2 1,-2 --------------------AUGCCUUGAGUGUAGGACCG--------------------------------------------------- 23 1,-1 --------------------AUGCCUUGAGUGUAGGACCGa-------------------------------------------------- 6 1,-1 --------------------AUGCCUUGAGUGUAGGACCGU-------------------------------------------------- 480 1,0 --------------------AUGCCUUGAGUGUAGGACCGUa------------------------------------------------- 2 1,0 --------------------AUGCCUUGAGUGUAGGACCGUU------------------------------------------------- 19 1,1 --------------------------------------------------------CCUCCCACACCCAAGGCU----------------- 5 0,-4 --------------------------------------------------------CCUCCCACACCCAAGGCUU---------------- 13 0,-3 --------------------------------------------------------CCUCCCACACCCAAGGCUUG--------------- 93 0,-2 --------------------------------------------------------CCUCCCACACCCAAGGCUUGa-------------- 17 0,-2 --------------------------------------------------------CCUCCCACACCCAAGGCUUGu-------------- 3 0,-2 --------------------------------------------------------CCUCCCACACCCAAGGCUUGC-------------- 543 0,-1 --------------------------------------------------------CCUCCCACACCCAAGGCUUGCc------------- 15 0,-1 --------------------------------------------------------CCUCCCACACCCAAGGCUUGCu------------- 2 0,-1 --------------------------------------------------------CCUCCCACACCCAAGGCUUGCA------------- 1387 0,0 --------------------------------------------------------CCUCCCACACCCAAGGCUUGCAg------------ 6 0,0 --------------------------------------------------------CCUCCCACACCCAAGGCUUGCAu------------ 48 0,0 --------------------------------------------------------CCUCCCACACCCAAGGCUUGCAA------------ 62 0,1 ---------------------------------------------------------CUCCCACACCCAAGGCUUGC-------------- 4 1,-1 ---------------------------------------------------------CUCCCACACCCAAGGCUUGCA------------- 49 1,0 ---------------------------------------------------------CUCCCACACCCAAGGCUUGCAu------------ 2 1,0 ----------------------------------------------------------UCCCACACCCAAGGCUUGC-------------- 2 2,-1 >hsa-mir-539 5pM:9-30 Tumor auacuugaGGAGAAAUUAUCCUUGGUGUGUucgcuuuauuuaugaugaaucauacaaggacaauuucuuuuugaguau --------GGAGAAAUUAUCCUUGGUGUGU------------------------------------------------ 8 0,0 --------GGAGAAAUUAUCCUUGGUGUGUU----------------------------------------------- 8 0,1 ----------AGAAAUUAUCCUUGGUGUGUU----------------------------------------------- 2 2,1 ------------------------------------------------AUCAUACAAGGACAAUUUCUU--------- 8 ------------------------------------------------AUCAUACAAGGACAAUUUCUUU-------- 229 ------------------------------------------------AUCAUACAAGGACAAUUUCUUUU------- 2 --------------------------------------------------CAUACAAGGACAAUUUCUUUUU------ 12 ---------------------------------------------------AUACAAGGACAAUUUCUUUU------- 2 ---------------------------------------------------AUACAAGGACAAUUUCUUUUU------ 15 ---------------------------------------------------AUACAAGGACAAUUUCUUUUUG----- 2 >hsa-mir-542 5p:16-38;3p:53-74 Tumor cagaucucagacaucUCGGGGAUCAUCAUGUCACGAGAuaccagugugcacuUGUGACAGAUUGAUAACUGAAAggucugggagccacucaucuuca --------------CUCGGGGAUCAUCAUGUCACG-------------------------------------------------------------- 3 -1,-3 --------------CUCGGGGAUCAUCAUGUCACGA------------------------------------------------------------- 20 -1,-2 ---------------UCGGGGAUCAUCAUGUCACG-------------------------------------------------------------- 8 0,-3 ---------------UCGGGGAUCAUCAUGUCACGA------------------------------------------------------------- 102 0,-2 ---------------UCGGGGAUCAUCAUGUCACGAG------------------------------------------------------------ 100 0,-1 ---------------UCGGGGAUCAUCAUGUCACGAGu----------------------------------------------------------- 11 0,-1 ---------------UCGGGGAUCAUCAUGUCACGAGA----------------------------------------------------------- 123 0,0 ---------------------------------------------------UUGUGACAGAUUGAUAACU--------------------------- 11 -1,-4 ---------------------------------------------------UUGUGACAGAUUGAUAACUG-------------------------- 11 -1,-3 ---------------------------------------------------UUGUGACAGAUUGAUAACUGA------------------------- 627 -1,-2 ---------------------------------------------------UUGUGACAGAUUGAUAACUGAu------------------------ 3 -1,-2 ---------------------------------------------------UUGUGACAGAUUGAUAACUGAA------------------------ 304 -1,-1 ---------------------------------------------------UUGUGACAGAUUGAUAACUGAAg----------------------- 2 -1,-1 ---------------------------------------------------UUGUGACAGAUUGAUAACUGAAu----------------------- 31 -1,-1 ---------------------------------------------------UUGUGACAGAUUGAUAACUGAAA----------------------- 117 -1,0 ----------------------------------------------------UGUGACAGAUUGAUAACU--------------------------- 4 0,-4 ----------------------------------------------------UGUGACAGAUUGAUAACUG-------------------------- 11 0,-3 ----------------------------------------------------UGUGACAGAUUGAUAACUGu------------------------- 6 0,-3 ----------------------------------------------------UGUGACAGAUUGAUAACUGA------------------------- 1391 0,-2 ----------------------------------------------------UGUGACAGAUUGAUAACUGAuu----------------------- 3 0,-2 ----------------------------------------------------UGUGACAGAUUGAUAACUGAA------------------------ 1294 0,-1 ----------------------------------------------------UGUGACAGAUUGAUAACUGAAc----------------------- 2 0,-1 ----------------------------------------------------UGUGACAGAUUGAUAACUGAAg----------------------- 2 0,-1 ----------------------------------------------------UGUGACAGAUUGAUAACUGAAu----------------------- 144 0,-1 ----------------------------------------------------UGUGACAGAUUGAUAACUGAAA----------------------- 2134 0,0 ----------------------------------------------------UGUGACAGAUUGAUAACUGAAAa---------------------- 78 0,0 ----------------------------------------------------UGUGACAGAUUGAUAACUGAAAu---------------------- 174 0,0 ----------------------------------------------------UGUGACAGAUUGAUAACUGAAAG---------------------- 70 0,1 ----------------------------------------------------UGUGACAGAUUGAUAACUGAAAGa--------------------- 2 0,1 ----------------------------------------------------UGUGACAGAUUGAUAACUGAAAGu--------------------- 2 0,1 -----------------------------------------------------GUGACAGAUUGAUAACUGA------------------------- 26 1,-2 -----------------------------------------------------GUGACAGAUUGAUAACUGAA------------------------ 31 1,-1 -----------------------------------------------------GUGACAGAUUGAUAACUGAAA----------------------- 65 1,0 >hsa-mir-543 3pM:47-68 Tumor uacuuaaugagaaguugcccguguuuuuuucgcuuuauuugugacgAAACAUUCGCGGUGCACUUCUUuuucaguauc ----------GAAGUUGCCCGUGUUUUUUUCG---------------------------------------------- 3 -----------AAGUUGCCCGUGUUUUUUUCG---------------------------------------------- 2 ----------------------------------------------AAACAUUCGCGGUGCACUUCU----------- 12 0,-1 ----------------------------------------------AAACAUUCGCGGUGCACUUCUU---------- 150 0,0 ----------------------------------------------AAACAUUCGCGGUGCACUUCUUa--------- 3 0,0 ----------------------------------------------AAACAUUCGCGGUGCACUUCUUU--------- 95 0,1 -----------------------------------------------AACAUUCGCGGUGCACUUCUU---------- 5 1,0 -----------------------------------------------AACAUUCGCGGUGCACUUCUUU--------- 2 1,1 >hsa-mir-544 3pM:55-76 Tumor auuuucaucaccuagggaucuuguuaaaaagcagauucugauucagggaccaagAUUCUGCAUUUUUAGCAAGUUCucaagugaugcuaau ------------------UCUUGUUAAAAAGCAGAUUCU---------------------------------------------------- 19 ------------------------------------------------------AUUCUGCAUUUUUAGCAAG------------------ 24 0,-3 ------------------------------------------------------AUUCUGCAUUUUUAGCAAGUU---------------- 8 0,-1 ------------------------------------------------------AUUCUGCAUUUUUAGCAAGUUu--------------- 4 0,-1 >hsa-mir-545 mi:25-46;MA:63-84 Tumor cccagccuggcacauuaguaggccUCAGUAAAUGUUUAUUAGAUGAauaaaugaaugacucaUCAGCAAACAUUUAUUGUGUGCcugcuaaagugagcuccacagg ------------------------UCAGUAAAUGUUUAUUAGAU-------------------------------------------------------------- 2 0,-2 ------------------------UCAGUAAAUGUUUAUUAGAUG------------------------------------------------------------- 23 0,-1 ------------------------UCAGUAAAUGUUUAUUAGAUGA------------------------------------------------------------ 153 0,0 -------------------------------------------------------------AUCAGCAAACAUUUAUUGUGU------------------------ 5 -1,-2 -------------------------------------------------------------AUCAGCAAACAUUUAUUGUGUG----------------------- 2 -1,-1 -------------------------------------------------------------AUCAGCAAACAUUUAUUGUGUGC---------------------- 4 -1,0 --------------------------------------------------------------UCAGCAAACAUUUAUUGUG------------------------- 2 0,-3 --------------------------------------------------------------UCAGCAAACAUUUAUUGUGUG----------------------- 30 0,-1 --------------------------------------------------------------UCAGCAAACAUUUAUUGUGUGa---------------------- 8 0,-1 --------------------------------------------------------------UCAGCAAACAUUUAUUGUGUGu---------------------- 22 0,-1 --------------------------------------------------------------UCAGCAAACAUUUAUUGUGUGC---------------------- 133 0,0 --------------------------------------------------------------UCAGCAAACAUUUAUUGUGUGCC--------------------- 11 0,1 ----------------------------------------------------------------AGCAAACAUUUAUUGUGUGC---------------------- 2 2,0 >hsa-mir-548a-1 3pM:61-82 Tumor ugcagggagguauuaaguuggugcaaaaguaauugugauuuuugccauuaaaaguaacgaCAAAACUGGCAAUUACUUUUGCaccaaaccugguauu ------------------------------------------------------------CAAAACUGGCAAUUACUUUU----------------- 5 0,-2 ------------------------------------------------------------CAAAACUGGCAAUUACUUUUG---------------- 29 0,-1 ------------------------------------------------------------CAAAACUGGCAAUUACUUUUGa--------------- 4 0,-1 ------------------------------------------------------------CAAAACUGGCAAUUACUUUUGC--------------- 45 0,0 >hsa-mir-548a-2 3pM:61-82 Tumor ugugauguguauuagguuugugcaaaaguaauugggguuuuuugccguuaaaaguaauggCAAAACUGGCAAUUACUUUUGCaccaaacuaauauaa ------------------------------------------------------------CAAAACUGGCAAUUACUUUU----------------- 5 0,-2 ------------------------------------------------------------CAAAACUGGCAAUUACUUUUG---------------- 29 0,-1 ------------------------------------------------------------CAAAACUGGCAAUUACUUUUGa--------------- 4 0,-1 ------------------------------------------------------------CAAAACUGGCAAUUACUUUUGC--------------- 45 0,0 >hsa-mir-548a-3 5p:25-46;3p:61-82 Tumor ccuagaauguuauuaggucggugcAAAAGUAAUUGCGAGUUUUACCauuacuuucaauggCAAAACUGGCAAUUACUUUUGCaccaacguaauacuu ------------------------AAAAGUAAUUGCGAGUUUUACC--------------------------------------------------- 4 0,0 ------------------------------------------------------------CAAAACUGGCAAUUACUUUU----------------- 5 0,-2 ------------------------------------------------------------CAAAACUGGCAAUUACUUUUG---------------- 29 0,-1 ------------------------------------------------------------CAAAACUGGCAAUUACUUUUGa--------------- 4 0,-1 ------------------------------------------------------------CAAAACUGGCAAUUACUUUUGC--------------- 45 0,0 >hsa-mir-548aa-1 3pM:55-79 Tumor cuuuauuagucuggugcaaaagaaacugugguuuuugccauuacuuuuacaggcAAAAACCACAAUUACUUUUGCACCAaccuaauauaacuuguuu ------------------------------------------------------AAAAACCACAAUUACUUUUGu---------------------- 2 0,-5 ------------------------------------------------------AAAAACCACAAUUACUUUUGC---------------------- 8 0,-4 ------------------------------------------------------AAAAACCACAAUUACUUUUGCA--------------------- 11 0,-3 --------------------------------------------------------AAACCACAAUUACUUUUGCACC------------------- 2 2,-1 >hsa-mir-548aa-2 3pM:55-79 Tumor uuuuauuagguuggugcaaaagaaacugugguuuuugccauuacuuucaauggcAAAAACCACAAUUACUUUUGCACCAaccuaaaucuucccucuc ------------------------------------------------------AAAAACCACAAUUACUUUUGu---------------------- 2 0,-5 ------------------------------------------------------AAAAACCACAAUUACUUUUGC---------------------- 8 0,-4 ------------------------------------------------------AAAAACCACAAUUACUUUUGCA--------------------- 11 0,-3 --------------------------------------------------------AAACCACAAUUACUUUUGCACC------------------- 2 2,-1 >hsa-mir-548ab 5pM:11-32 Tumor auguuggugcAAAAGUAAUUGUGGAUUUUGCUauuacuuguauuuauuuguaaugcaaaacccgcaauuaguuuugcaccaacc ----------AAAAGUAAUUGUGGAUUUUGC----------------------------------------------------- 2 0,-1 ----------AAAAGUAAUUGUGGAUUUUGCU---------------------------------------------------- 12 0,0 >hsa-mir-548ac 3pM:53-74 Tumor guauuagguuggugcaaaaguuauugugguuuuugcuauuuuuuuuuaauggCAAAAACCGGCAAUUACUUUUGcacuaaccuaguag ---------------AAAAGUUAUUGUGGUUUUUGCU--------------------------------------------------- 2 >hsa-mir-548ad 3pM:49-70 Tumor cuguuagguuggugcaaaaguaauugugguuuuugaaaguaacuuggcGAAAACGACAAUGACUUUUGCAccaaucuaauac --------------CAAAAGUAAUUGUGGUUUU------------------------------------------------- 2 --------------CAAAAGUAAUUGUGGUUUUU------------------------------------------------ 4 --------------CAAAAGUAAUUGUGGUUUUUG----------------------------------------------- 6 --------------CAAAAGUAAUUGUGGUUUUUGA---------------------------------------------- 2 ---------------AAAAGUAAUUGUGGUUUU------------------------------------------------- 2 ---------------AAAAGUAAUUGUGGUUUUU------------------------------------------------ 9 ---------------AAAAGUAAUUGUGGUUUUUG----------------------------------------------- 18 ---------------AAAAGUAAUUGUGGUUUUUGA---------------------------------------------- 2 >hsa-mir-548ae-2 3pM:43-63 Tumor ugugcaaaaguaauugugguuuuugucauuuaaaaguaauggCAAAAACUGCAAUUACUUUCAcacc ----CAAAAGUAAUUGUGGUUUU-------------------------------------------- 2 ----CAAAAGUAAUUGUGGUUUUU------------------------------------------- 4 ----CAAAAGUAAUUGUGGUUUUUG------------------------------------------ 6 ----CAAAAGUAAUUGUGGUUUUUGU----------------------------------------- 23 -----AAAAGUAAUUGUGGUUUU-------------------------------------------- 2 -----AAAAGUAAUUGUGGUUUUU------------------------------------------- 9 -----AAAAGUAAUUGUGGUUUUUG------------------------------------------ 18 -----AAAAGUAAUUGUGGUUUUUGU----------------------------------------- 4 -----AAAAGUAAUUGUGGUUUUUGUu---------------------------------------- 2 >hsa-mir-548ah 5pM:11-30 Tumor agguuggugcAAAAGUGAUUGCAGUGUUUGccaauaaaaguaaugacaaaaacugcaguuacuuuugcaccagccc ---------------------------------------------ACAAAAACUGCAGUUACUUUU---------- 2 ----------------------------------------------CAAAAACUGCAGUUACUUUUG--------- 2 ----------------------------------------------CAAAAACUGCAGUUACUUUUGC-------- 2 -----------------------------------------------AAAAACUGCAGUUACUUUUGCA------- 6 >hsa-mir-548ai 5pM:16-37 Tumor guauuagguuggugcAAAGGUAAUUGCAGUUUUUCCCauuuaaaauauggaaaaaaaaaucacaauuacuuuugcaucaaccuaauaa ---------------AAAGGUAAUUGCAGUUUUUC----------------------------------------------------- 4 0,-2 ---------------AAAGGUAAUUGCAGUUUUUCC---------------------------------------------------- 15 0,-1 ---------------AAAGGUAAUUGCAGUUUUUCCC--------------------------------------------------- 6 0,0 ---------------AAAGGUAAUUGCAGUUUUUCCCA-------------------------------------------------- 2 0,1 >hsa-mir-548aj-2 3pM:55-75 Tumor aagguauuagguuggugcaaaaguaauugcaguuuuugcuauuacuuuuaauggUAAAAACUGCAAUUACUUUUAcaccaaccuaauauuua -----------UUGGUGCAAAAGUAAUUGCu------------------------------------------------------------- 2 -----------------CAAAAGUAAUUGCAGUUUUU------------------------------------------------------- 2 ------------------AAAAGUAAUUGCAGUUUUUG------------------------------------------------------ 10 ------------------AAAAGUAAUUGCAGUUUUUGa----------------------------------------------------- 2 ------------------AAAAGUAAUUGCAGUUUUUGCc---------------------------------------------------- 2 --------------------AAGUAAUUGCAGUUUUUG------------------------------------------------------ 2 >hsa-mir-548ak 5pM:5-25 Tumor gugcAAAAGUAACUGCGGUUUUUGAgaaguaauugaaaaccgcaauuacuuuugcag ---CAAAAGUAACUGCGGUUUUUG--------------------------------- 4 -1,-1 ---CAAAAGUAACUGCGGUUUUUGA-------------------------------- 2 -1,0 ----AAAAGUAACUGCGGUUUUU---------------------------------- 2 0,-2 ----AAAAGUAACUGCGGUUUUUG--------------------------------- 15 0,-1 ----AAAAGUAACUGCGGUUUUUGA-------------------------------- 4 0,0 >hsa-mir-548am 3pM:46-67 Tumor aguuggugcaaaaguaauugcgguuuuugccgucgaaaauaauggCAAAAACUGCAGUUACUUUUGUaccaaug --UUGGUGCAAAAGUAAUUGCu---------------------------------------------------- 2 -------GCAAAAGUAAUUGCGGUUUUUGu-------------------------------------------- 2 --------CAAAAGUAAUUGCGGUUUUUG--------------------------------------------- 11 --------CAAAAGUAAUUGCGGUUUUUGC-------------------------------------------- 10 ---------AAAAGUAAUUGCGGUUUUU---------------------------------------------- 8 ---------AAAAGUAAUUGCGGUUUUUu--------------------------------------------- 2 ---------AAAAGUAAUUGCGGUUUUUG--------------------------------------------- 52 ---------AAAAGUAAUUGCGGUUUUUGa-------------------------------------------- 9 ---------AAAAGUAAUUGCGGUUUUUGC-------------------------------------------- 57 ---------AAAAGUAAUUGCGGUUUUUGCa------------------------------------------- 2 ---------AAAAGUAAUUGCGGUUUUUGCu------------------------------------------- 9 ---------AAAAGUAAUUGCGGUUUUUGCC------------------------------------------- 65 ----------AAAGUAAUUGCGGUUUUU---------------------------------------------- 2 ----------AAAGUAAUUGCGGUUUUUG--------------------------------------------- 4 ----------AAAGUAAUUGCGGUUUUUGC-------------------------------------------- 4 ----------AAAGUAAUUGCGGUUUUUGCC------------------------------------------- 4 ---------------------------------------------CAAAAACUGCAGUUACUUUUG-------- 2 0,-1 >hsa-mir-548b 5p:25-46;3p:61-82 Tumor cagacuauauauuuagguuggcgcAAAAGUAAUUGUGGUUUUGGCCuuuauuuucaauggCAAGAACCUCAGUUGCUUUUGUgccaaccuaauacuu -----------------------CAAAAGUAAUUGUGGUUUU------------------------------------------------------- 2 -1,-4 ------------------------AAAAGUAAUUGUGGUUUU------------------------------------------------------- 2 0,-4 ------------------------AAAAGUAAUUGUGGUUUUGGCC--------------------------------------------------- 2 0,0 ------------------------------------------------------------CAAGAACCUCAGUUGCUUUU----------------- 2 0,-2 ------------------------------------------------------------CAAGAACCUCAGUUGCUUUUG---------------- 45 0,-1 ------------------------------------------------------------CAAGAACCUCAGUUGCUUUUGU--------------- 184 0,0 -------------------------------------------------------------AAGAACCUCAGUUGCUUUU----------------- 2 1,-2 -------------------------------------------------------------AAGAACCUCAGUUGCUUUUGU--------------- 2 1,0 >hsa-mir-548c 5p:25-46;3p:61-82 Tumor cauuggcaucuauuagguuggugcAAAAGUAAUUGCGGUUUUUGCCauuacuuucaguagCAAAAAUCUCAAUUACUUUUGCaccaacuuaauacuu ----------------------GCAAAAGUAAUUGCGGUUUUUGu---------------------------------------------------- 2 -2,-2 -----------------------CAAAAGUAAUUGCGGUUUUUG----------------------------------------------------- 11 -1,-2 -----------------------CAAAAGUAAUUGCGGUUUUUGC---------------------------------------------------- 10 -1,-1 ------------------------AAAAGUAAUUGCGGUUUUU------------------------------------------------------ 8 0,-3 ------------------------AAAAGUAAUUGCGGUUUUUu----------------------------------------------------- 2 0,-3 ------------------------AAAAGUAAUUGCGGUUUUUG----------------------------------------------------- 52 0,-2 ------------------------AAAAGUAAUUGCGGUUUUUGa---------------------------------------------------- 9 0,-2 ------------------------AAAAGUAAUUGCGGUUUUUGC---------------------------------------------------- 57 0,-1 ------------------------AAAAGUAAUUGCGGUUUUUGCa--------------------------------------------------- 2 0,-1 ------------------------AAAAGUAAUUGCGGUUUUUGCu--------------------------------------------------- 9 0,-1 ------------------------AAAAGUAAUUGCGGUUUUUGCC--------------------------------------------------- 65 0,0 -------------------------AAAGUAAUUGCGGUUUUU------------------------------------------------------ 2 1,-3 -------------------------AAAGUAAUUGCGGUUUUUG----------------------------------------------------- 4 1,-2 -------------------------AAAGUAAUUGCGGUUUUUGC---------------------------------------------------- 4 1,-1 -------------------------AAAGUAAUUGCGGUUUUUGCC--------------------------------------------------- 4 1,0 -------------------------AAAGUAAUUGCGGUUUUUGCCA-------------------------------------------------- 11 1,1 >hsa-mir-548d-1 5p:25-46;3p:61-82 Tumor aaacaaguuauauuagguuggugcAAAAGUAAUUGUGGUUUUUGCCuguaaaaguaauggCAAAAACCACAGUUUCUUUUGCaccagacuaauaaag -----------------------CAAAAGUAAUUGUGGUUUU------------------------------------------------------- 2 -1,-4 -----------------------CAAAAGUAAUUGUGGUUUUU------------------------------------------------------ 4 -1,-3 -----------------------CAAAAGUAAUUGUGGUUUUUG----------------------------------------------------- 6 -1,-2 -----------------------CAAAAGUAAUUGUGGUUUUUGC---------------------------------------------------- 4 -1,-1 ------------------------AAAAGUAAUUGUGGUUUU------------------------------------------------------- 2 0,-4 ------------------------AAAAGUAAUUGUGGUUUUU------------------------------------------------------ 9 0,-3 ------------------------AAAAGUAAUUGUGGUUUUUG----------------------------------------------------- 18 0,-2 ------------------------AAAAGUAAUUGUGGUUUUUGC---------------------------------------------------- 60 0,-1 ------------------------AAAAGUAAUUGUGGUUUUUGCa--------------------------------------------------- 6 0,-1 ------------------------AAAAGUAAUUGUGGUUUUUGCu--------------------------------------------------- 2 0,-1 ------------------------AAAAGUAAUUGUGGUUUUUGCC--------------------------------------------------- 54 0,0 -------------------------AAAGUAAUUGUGGUUUUUGC---------------------------------------------------- 2 1,-1 -------------------------AAAGUAAUUGUGGUUUUUGCu--------------------------------------------------- 4 1,-1 -------------------------AAAGUAAUUGUGGUUUUUGCC--------------------------------------------------- 4 1,0 ------------------------------------------------------------CAAAAACCACAGUUUCUUUUG---------------- 3 0,-1 ------------------------------------------------------------CAAAAACCACAGUUUCUUUUGC--------------- 16 0,0 >hsa-mir-548d-2 5p:25-46;3p:61-82 Tumor gagagggaagauuuagguuggugcAAAAGUAAUUGUGGUUUUUGCCauugaaaguaauggCAAAAACCACAGUUUCUUUUGCaccaaccuaauaaaa -----------------------CAAAAGUAAUUGUGGUUUU------------------------------------------------------- 2 -1,-4 -----------------------CAAAAGUAAUUGUGGUUUUU------------------------------------------------------ 4 -1,-3 -----------------------CAAAAGUAAUUGUGGUUUUUG----------------------------------------------------- 6 -1,-2 -----------------------CAAAAGUAAUUGUGGUUUUUGC---------------------------------------------------- 4 -1,-1 ------------------------AAAAGUAAUUGUGGUUUU------------------------------------------------------- 2 0,-4 ------------------------AAAAGUAAUUGUGGUUUUU------------------------------------------------------ 9 0,-3 ------------------------AAAAGUAAUUGUGGUUUUUG----------------------------------------------------- 18 0,-2 ------------------------AAAAGUAAUUGUGGUUUUUGC---------------------------------------------------- 60 0,-1 ------------------------AAAAGUAAUUGUGGUUUUUGCa--------------------------------------------------- 6 0,-1 ------------------------AAAAGUAAUUGUGGUUUUUGCu--------------------------------------------------- 2 0,-1 ------------------------AAAAGUAAUUGUGGUUUUUGCC--------------------------------------------------- 54 0,0 -------------------------AAAGUAAUUGUGGUUUUUGC---------------------------------------------------- 2 1,-1 -------------------------AAAGUAAUUGUGGUUUUUGCu--------------------------------------------------- 4 1,-1 -------------------------AAAGUAAUUGUGGUUUUUGCC--------------------------------------------------- 4 1,0 ------------------------------------------------------------CAAAAACCACAGUUUCUUUUG---------------- 3 0,-1 ------------------------------------------------------------CAAAAACCACAGUUUCUUUUGC--------------- 16 0,0 >hsa-mir-548e 3pM:53-74 Tumor uuauuagguugguacaaaagcaaucgcgguuuuugcuauuacuuuuaaaggcAAAAACUGAGACUACUUUUGCAccaaccugauagaa -----------GUACAAAAGCAAUCGCGGUUUU------------------------------------------------------- 2 --------------CAAAAGCAAUCGCGGUUUUUG----------------------------------------------------- 4 --------------CAAAAGCAAUCGCGGUUUUUGC---------------------------------------------------- 10 ---------------AAAAGCAAUCGCGGUUUUUG----------------------------------------------------- 2 ---------------AAAAGCAAUCGCGGUUUUUGCU--------------------------------------------------- 8 ---------------------------------------------------CAAAAACUGAGACUACUUUUG---------------- 2 -1,-2 ---------------------------------------------------CAAAAACUGAGACUACUUUUGCA-------------- 2 -1,0 ----------------------------------------------------AAAAACUGAGACUACUUUU----------------- 10 0,-3 ----------------------------------------------------AAAAACUGAGACUACUUUUG---------------- 116 0,-2 ----------------------------------------------------AAAAACUGAGACUACUUUUGa--------------- 3 0,-2 ----------------------------------------------------AAAAACUGAGACUACUUUUGC--------------- 141 0,-1 ----------------------------------------------------AAAAACUGAGACUACUUUUGCu-------------- 2 0,-1 ----------------------------------------------------AAAAACUGAGACUACUUUUGCA-------------- 337 0,0 ----------------------------------------------------AAAAACUGAGACUACUUUUGCAa------------- 38 0,0 -----------------------------------------------------AAAACUGAGACUACUUUUGC--------------- 8 1,-1 -----------------------------------------------------AAAACUGAGACUACUUUUGCA-------------- 16 1,0 -----------------------------------------------------AAAACUGAGACUACUUUUGCAu------------- 2 1,0 >hsa-mir-548f-2 3pM:59-77 Tumor uaauaacuauuagguuggugcgaacauaauugcaguuuuuaucauuacuuuuaauggcAAAAACUGUAAUUACUUUUgcaccaaccuaauauuuuagu ---------------------------------------------------------CAAAAACUGUAAUUACUUUUGC------------------- 3 -1,2 >hsa-mir-548f-3 3pM:54-72 Tumor auuagguuggugcaaaccuaauugcaauuuuugcaguuuuuuuaaguaauugcAAAAACUGUAAUUACUUUUgcaccaaccuaauac ----------------------------------------------------CAAAAACUGUAAUUACUUUUGC------------- 3 -1,2 >hsa-mir-548g 3pM:54-75 Tumor aguuauuagauuagugcaaaaguaauugcaguuuuugcauuacguucuauggcAAAACUGUAAUUACUUUUGUACcaacauaauacuuc ----------------CAAAAGUAAUUGCAGUUUUU----------------------------------------------------- 2 -----------------AAAAGUAAUUGCAGUUUUUG---------------------------------------------------- 10 -----------------AAAAGUAAUUGCAGUUUUUGa--------------------------------------------------- 2 -----------------AAAAGUAAUUGCAGUUUUUGCc-------------------------------------------------- 2 -------------------AAGUAAUUGCAGUUUUUG---------------------------------------------------- 2 >hsa-mir-548h-3 5pM:29-50 Tumor ucugauucugcauguauuagguuggugcAAAAGUAAUCGCGGUUUUUGUCauugaaaguaauagcaaaaacugcaauuacuuuugcaccaaccuaaaaguagucacugucuucagaua ----------------------------------------------------------------CAAAAACUGCAAUUACUUUUG--------------------------------- 10 ----------------------------------------------------------------CAAAAACUGCAAUUACUUUUGu-------------------------------- 6 ----------------------------------------------------------------CAAAAACUGCAAUUACUUUUGC-------------------------------- 33 -----------------------------------------------------------------AAAAACUGCAAUUACUUUUGCA------------------------------- 3 >hsa-mir-548h-4 5pM:17-38 Tumor gcuauuagguuggugcAAAAGUAAUCGCGGUUUUUGUCauuacuuuaauuacuuuacguuucauuaaugacaaaaaccgcaauuacuuuugcaccaaccuaauacuugcua ----------------------------------------------------------------------CAAAAACCGCAAUUACUU----------------------- 2 ----------------------------------------------------------------------CAAAAACCGCAAUUACUUUU--------------------- 2 ----------------------------------------------------------------------CAAAAACCGCAAUUACUUUUG-------------------- 2 ----------------------------------------------------------------------CAAAAACCGCAAUUACUUUUGC------------------- 12 ----------------------------------------------------------------------CAAAAACCGCAAUUACUUUUGCA------------------ 2 -----------------------------------------------------------------------AAAAACCGCAAUUACUUUUGC------------------- 4 -----------------------------------------------------------------------AAAAACCGCAAUUACUUUUGCA------------------ 4 >hsa-mir-548i-1 5pM:39-60 Tumor cagauggcucugaaguuugcacccuauuagguuggugcAAAAGUAAUUGCGGAUUUUGCCauuaaaaguaauggcaaaaauagcaauuauuuuuguaccagccuaguaucuuuucuccuucuaccaaacuuugucccugagccaucuca --------------------------------------AAAAGUAAUUGCGGAUUUUGCC----------------------------------------------------------------------------------------- 7 0,0 >hsa-mir-548i-2 5pM:39-60 Tumor uagauggcuccgaaguuugcauccuauuaguuuggugcAAAAGUAAUUGCGGAUUUUGCCauuaaaaguaauggcaaaaauagcaauuauuuuuguaccagccuaguaucuuuucuccuucuaacaaaguucgucccugauccaucuca --------------------------------------AAAAGUAAUUGCGGAUUUUGCC----------------------------------------------------------------------------------------- 7 0,0 >hsa-mir-548i-3 5pM:39-60 Tumor cagauggcuccgaaguuuacauccuauuagguuugugcAAAAGUAAUUGCGGAUUUUGCCauuaaaaguaauggcaaaaauagcaauuauuuuuguaccagccuaguaucuuuucuccuucuaccaaacuuugucccugagccaucuca --------------------------------------AAAAGUAAUUGCGGAUUUUGCC----------------------------------------------------------------------------------------- 7 0,0 >hsa-mir-548i-4 5pM:11-32 Tumor agguuggugcAAAAGUAAUUGCGGAUUUUGCCauacuuuuaacggcaaaaaccacaaauauuauugcaccaaccuau ----------AAAAGUAAUUGCGGAUUUUGCC--------------------------------------------- 7 0,0 >hsa-mir-548j 5pM:29-50 Tumor gggcagccagugaauaguuagcuggugcAAAAGUAAUUGCGGUCUUUGGUauuacuuucaguggcaaaaacugcauuacuuuugcaccagccuacuagaacgcugaguucag ---------------------------CAAAAGUAAUUGCGGUCUUUGG--------------------------------------------------------------- 4 -1,-1 ---------------------------CAAAAGUAAUUGCGGUCUUUGGU-------------------------------------------------------------- 9 -1,0 ----------------------------AAAAGUAAUUGCGGUCUUUGGU-------------------------------------------------------------- 15 0,0 --------------------------------------------------------------------------AUUACUUUUGCACCAGCCUA------------------ 2 >hsa-mir-548k 5pM:32-53 Tumor cuuuucucaaguauugcuguuagguuggugcAAAAGUACUUGCGGAUUUUGCUuuacuuuuaauggcaaaaaccgcaauuauuuuugcuucaaccuaauaugaugcaaaauuggcu -------------------------------AAAAGUACUUGCGGAUUUU------------------------------------------------------------------ 2 0,-3 -------------------------------AAAAGUACUUGCGGAUUUUG----------------------------------------------------------------- 13 0,-2 -------------------------------AAAAGUACUUGCGGAUUUUGC---------------------------------------------------------------- 12 0,-1 -------------------------------AAAAGUACUUGCGGAUUUUGCU--------------------------------------------------------------- 242 0,0 -------------------------------AAAAGUACUUGCGGAUUUUGCUU-------------------------------------------------------------- 2 0,1 --------------------------------------------------------------------AAAACCGCAAUUAUUUUUGCU--------------------------- 2 >hsa-mir-548l 5pM:15-36 Tumor uauuagguuggugcAAAAGUAUUUGCGGGUUUUGUCguagaaaguaauggcaaaaacugcaguuacuugugcaccaaccaaaugcu --------------AAAAGUAUUUGCGGGUUUUGU--------------------------------------------------- 4 0,-1 >hsa-mir-548n 5pM:10-31 Tumor agguuggugCAAAAGUAAUUGUGGAUUUUGUcguuaaaaauagcaaaacccgcaauuacuuuugcaccaaccuaa ---------CAAAAGUAAUUGUGGAUUUUGU-------------------------------------------- 2 0,0 ---------------------------------------------AAACCCGCAAUUACUUUUGCA--------- 2 >hsa-mir-548o 3pM:87-108 Tumor uggugaaaauguguugauuguaaugguuccuauucugaucaauaaacaugguuugagccuaguuacaaugaucuaaaauucacgguCCAAAACUGCAGUUACUUUUGCaccaac --------------------------------------------------------------------------------------CCAAAACUGCAGUUACUUUU-------- 12 0,-2 --------------------------------------------------------------------------------------CCAAAACUGCAGUUACUUUUG------- 81 0,-1 --------------------------------------------------------------------------------------CCAAAACUGCAGUUACUUUUGa------ 2 0,-1 --------------------------------------------------------------------------------------CCAAAACUGCAGUUACUUUUGC------ 83 0,0 >hsa-mir-548o-2 3pM:45-66 Tumor uggugcaaaaguaauugcgguuuuugccauuaaaaguaaugcggCCAAAACUGCAGUUACUUUUGCaccc ----GCAAAAGUAAUUGCGGUUUUUGu------------------------------------------- 2 -----CAAAAGUAAUUGCGGUUUUUG-------------------------------------------- 11 -----CAAAAGUAAUUGCGGUUUUUGC------------------------------------------- 10 ------AAAAGUAAUUGCGGUUUUU--------------------------------------------- 8 ------AAAAGUAAUUGCGGUUUUUu-------------------------------------------- 2 ------AAAAGUAAUUGCGGUUUUUG-------------------------------------------- 52 ------AAAAGUAAUUGCGGUUUUUGa------------------------------------------- 9 ------AAAAGUAAUUGCGGUUUUUGC------------------------------------------- 57 ------AAAAGUAAUUGCGGUUUUUGCa------------------------------------------ 2 ------AAAAGUAAUUGCGGUUUUUGCu------------------------------------------ 9 ------AAAAGUAAUUGCGGUUUUUGCC------------------------------------------ 65 -------AAAGUAAUUGCGGUUUUU--------------------------------------------- 2 -------AAAGUAAUUGCGGUUUUUG-------------------------------------------- 4 -------AAAGUAAUUGCGGUUUUUGC------------------------------------------- 4 -------AAAGUAAUUGCGGUUUUUGCC------------------------------------------ 4 -------AAAGUAAUUGCGGUUUUUGCCA----------------------------------------- 11 --------------------------------------------CCAAAACUGCAGUUACUUUU------ 12 0,-2 --------------------------------------------CCAAAACUGCAGUUACUUUUG----- 81 0,-1 --------------------------------------------CCAAAACUGCAGUUACUUUUGa---- 2 0,-1 --------------------------------------------CCAAAACUGCAGUUACUUUUGC---- 83 0,0 >hsa-mir-548s 3pM:52-74 Tumor uugcugcaaaaauaauugcaguuuuugccauuauuuuuaauaauuauaauaAUGGCCAAAACUGCAGUUAUUUUugcaccaa -----------AUAAUUGCAGUUUUUGCCAUU-------------------------------------------------- 2 -----------AUAAUUGCAGUUUUUGCCAUUA------------------------------------------------- 2 ---------------------------------------------------AUGGCCAAAACUGCAGUUAUU---------- 2 0,-2 ---------------------------------------------------AUGGCCAAAACUGCAGUUAUUU--------- 3 0,-1 >hsa-mir-548t 5pM:10-30 Tumor aggguggugCAAAAGUGAUCGUGGUUUUUGcaauuuuuuaaugacaaaaaccacaauuacuuuugcaccaaccu ---------------------------------------------AAAAACCACAAUUACUUUUGu-------- 2 ---------------------------------------------AAAAACCACAAUUACUUUUGC-------- 8 ---------------------------------------------AAAAACCACAAUUACUUUUGCA------- 11 -----------------------------------------------AAACCACAAUUACUUUUGCACC----- 2 >hsa-mir-548u 3pM:49-71 Tumor auuaggauggugcaaaaguaaugugguuuuuuucuuuacuuuuaauggCAAAGACUGCAAUUACUUUUGCGccaaccuaau ------------------------------------------------CAAAGACUGCAAUUACUUUUGC----------- 2 0,-1 >hsa-mir-548v 3pM:49-70 Tumor aauacuagguuugagcaaaaguaauugcgguuuugccaucaugccaaaAGCUACAGUUACUUUUGCACCAgccuaauauu ------------GAGCAAAAGUAAUUGCGGUUU----------------------------------------------- 7 ------------GAGCAAAAGUAAUUGCGGUUUU---------------------------------------------- 9 ------------------------------------------------AGCUACAGUUACUUUUGCACC----------- 2 0,-1 ------------------------------------------------AGCUACAGUUACUUUUGCACCA---------- 2 0,0 ------------------------------------------------AGCUACAGUUACUUUUGCACCAu--------- 4 0,0 >hsa-mir-548w 5pM:10-32 Tumor gguuggugcAAAAGUAACUGCGGUUUUUGCCUuucaacauaauggcaaaacccacaauuacuuuugcaccaauc --------CAAAAGUAACUGCGGUUUUUG--------------------------------------------- 4 -1,-3 --------CAAAAGUAACUGCGGUUUUUGC-------------------------------------------- 8 -1,-2 ---------AAAAGUAACUGCGGUUUUU---------------------------------------------- 2 0,-4 ---------AAAAGUAACUGCGGUUUUUG--------------------------------------------- 15 0,-3 ---------AAAAGUAACUGCGGUUUUUGC-------------------------------------------- 35 0,-2 ---------AAAAGUAACUGCGGUUUUUGCC------------------------------------------- 50 0,-1 >hsa-mir-548x 3pM:46-65 Tumor agguuagugcaaaaguaauugcaguuuuugcguuacuuucaaucgUAAAAACUGCAAUUACUUUCacaccaaucu ---------CAAAAGUAAUUGCAGUUUUU---------------------------------------------- 2 ----------AAAAGUAAUUGCAGUUUUUG--------------------------------------------- 10 ----------AAAAGUAAUUGCAGUUUUUGa-------------------------------------------- 2 ----------AAAAGUAAUUGCAGUUUUUGCc------------------------------------------- 2 ------------AAGUAAUUGCAGUUUUUG--------------------------------------------- 2 ---------------------------------------------UAAAAACUGCAAUUACUUUCA--------- 2 0,1 >hsa-mir-548y 5pM:23-44 Tumor gccuaaacuauuagguuggugcAAAAGUAAUCACUGUUUUUGCCauuacucucaguggcaaaaaccgugauuacuuuugcaccaaccuaguaacaccuucacuguggggg ----------------------------------------------------------CAAAAACCGUGAUUACUUUUGC------------------------------ 2 >hsa-mir-548z 3pM:54-76 Tumor aaguauuaaguuggugcaaaaguaauugagauuuuugcuacugaaaguaauggCAAAAACCGCAAUUACUUUUGCAccaaccuaauagaugccaaug -----------------------------------------------------CAAAAACCGCAAUUACUU-------------------------- 2 0,-5 -----------------------------------------------------CAAAAACCGCAAUUACUUUU------------------------ 2 0,-3 -----------------------------------------------------CAAAAACCGCAAUUACUUUUG----------------------- 2 0,-2 -----------------------------------------------------CAAAAACCGCAAUUACUUUUGC---------------------- 12 0,-1 -----------------------------------------------------CAAAAACCGCAAUUACUUUUGCA--------------------- 2 0,0 ------------------------------------------------------AAAAACCGCAAUUACUUUUGC---------------------- 4 1,-1 ------------------------------------------------------AAAAACCGCAAUUACUUUUGCA--------------------- 4 1,0 >hsa-mir-549 3pM:61-81 Tumor agacaugcaacucaagaauauauugagagcucauccauaguugucacugucucaaaucagUGACAACUAUGGAUGAGCUCUuaauauaucccaggc ---------------------------AGCUCAUCCAUAGUUGUCACUG----------------------------------------------- 3 >hsa-mir-550a-1 MA:22-44;mi:61-82 Tumor ugaugcuuugcuggcuggugcAGUGCCUGAGGGAGUAAGAGCCCuguuguuguaagauagUGUCUUACUCCCUCAGGCACAUcuccaacaagucucu ---------------------AGUGCCUGAGGGAGUAAGA--------------------------------------------------------- 6 0,-4 ---------------------AGUGCCUGAGGGAGUAAGAG-------------------------------------------------------- 4 0,-3 ---------------------AGUGCCUGAGGGAGUAAGAGa------------------------------------------------------- 2 0,-3 ---------------------AGUGCCUGAGGGAGUAAGAGC------------------------------------------------------- 22 0,-2 ---------------------AGUGCCUGAGGGAGUAAGAGCC------------------------------------------------------ 2 0,-1 ---------------------AGUGCCUGAGGGAGUAAGAGCCC----------------------------------------------------- 2 0,0 ----------------------GUGCCUGAGGGAGUAAGAGC------------------------------------------------------- 2 1,-2 -----------------------UGCCUGAGGGAGUAAGAGCCCU---------------------------------------------------- 2 2,1 -----------------------UGCCUGAGGGAGUAAGAGCCCUuu-------------------------------------------------- 2 2,1 ------------------------------------------------------------UGUCUUACUCCCUCAGGCA------------------ 5 0,-3 ------------------------------------------------------------UGUCUUACUCCCUCAGGCAC----------------- 2 0,-2 ------------------------------------------------------------UGUCUUACUCCCUCAGGCACA---------------- 58 0,-1 ------------------------------------------------------------UGUCUUACUCCCUCAGGCACAa--------------- 2 0,-1 ------------------------------------------------------------UGUCUUACUCCCUCAGGCACAU--------------- 101 0,0 ------------------------------------------------------------UGUCUUACUCCCUCAGGCACAUu-------------- 5 0,0 -------------------------------------------------------------GUCUUACUCCCUCAGGCACAUC-------------- 2 1,1 >hsa-mir-550a-2 MA:22-44;mi:61-82 Tumor ugaugcuuugcuggcuggugcAGUGCCUGAGGGAGUAAGAGCCCuguuguugucagauagUGUCUUACUCCCUCAGGCACAUcuccagcgagucucu ---------------------AGUGCCUGAGGGAGUAAGA--------------------------------------------------------- 6 0,-4 ---------------------AGUGCCUGAGGGAGUAAGAG-------------------------------------------------------- 4 0,-3 ---------------------AGUGCCUGAGGGAGUAAGAGa------------------------------------------------------- 2 0,-3 ---------------------AGUGCCUGAGGGAGUAAGAGC------------------------------------------------------- 22 0,-2 ---------------------AGUGCCUGAGGGAGUAAGAGCC------------------------------------------------------ 2 0,-1 ---------------------AGUGCCUGAGGGAGUAAGAGCCC----------------------------------------------------- 2 0,0 ----------------------GUGCCUGAGGGAGUAAGAGC------------------------------------------------------- 2 1,-2 -----------------------UGCCUGAGGGAGUAAGAGCCCU---------------------------------------------------- 2 2,1 -----------------------UGCCUGAGGGAGUAAGAGCCCUuu-------------------------------------------------- 2 2,1 ------------------------------------------------------------UGUCUUACUCCCUCAGGCA------------------ 5 0,-3 ------------------------------------------------------------UGUCUUACUCCCUCAGGCAC----------------- 2 0,-2 ------------------------------------------------------------UGUCUUACUCCCUCAGGCACA---------------- 58 0,-1 ------------------------------------------------------------UGUCUUACUCCCUCAGGCACAa--------------- 2 0,-1 ------------------------------------------------------------UGUCUUACUCCCUCAGGCACAU--------------- 101 0,0 ------------------------------------------------------------UGUCUUACUCCCUCAGGCACAUu-------------- 5 0,0 -------------------------------------------------------------GUCUUACUCCCUCAGGCACAUC-------------- 2 1,1 >hsa-mir-550a-3 3pM:60-81 Tumor gaugcuuugcuggcuggugcagugccugagggaguaagaguccuguuguuguaagauagUGUCUUACUCCCUCAGGCACAUcuccaacaagucuc --------------------AGUGCCUGAGGGAGUAAGA-------------------------------------------------------- 6 --------------------AGUGCCUGAGGGAGUAAGAG------------------------------------------------------- 4 --------------------AGUGCCUGAGGGAGUAAGAGa------------------------------------------------------ 2 ----------------------UGCCUGAGGGAGUAAGAGUCC---------------------------------------------------- 4 -----------------------------------------------------------UGUCUUACUCCCUCAGGCA----------------- 5 0,-3 -----------------------------------------------------------UGUCUUACUCCCUCAGGCAC---------------- 2 0,-2 -----------------------------------------------------------UGUCUUACUCCCUCAGGCACA--------------- 58 0,-1 -----------------------------------------------------------UGUCUUACUCCCUCAGGCACAa-------------- 2 0,-1 -----------------------------------------------------------UGUCUUACUCCCUCAGGCACAU-------------- 101 0,0 -----------------------------------------------------------UGUCUUACUCCCUCAGGCACAUu------------- 5 0,0 ------------------------------------------------------------GUCUUACUCCCUCAGGCACAUC------------- 2 1,1 >hsa-mir-551a 3pM:61-81 Tumor ggggacugccgggugacccuggaaauccagaguggguggggccagucugaccguuucuagGCGACCCACUCUUGGUUUCCAggguugcccuggaaa ------------------------------------------------------------GCGACCCACUCUUGGUUU------------------ 2 0,-3 ------------------------------------------------------------GCGACCCACUCUUGGUUUC----------------- 2 0,-2 ------------------------------------------------------------GCGACCCACUCUUGGUUUCC---------------- 5 0,-1 ------------------------------------------------------------GCGACCCACUCUUGGUUUCCA--------------- 25 0,0 >hsa-mir-551b mi:22-43;MA:61-81 Tumor agaugugcucuccuggcccauGAAAUCAAGCGUGGGUGAGACCuggugcagaacgggaagGCGACCCAUACUUGGUUUCAGaggcugugagaauaa ------------------------------------------------------------GCGACCCAUACUUGGUUUCA---------------- 8 0,-1 ------------------------------------------------------------GCGACCCAUACUUGGUUUCAG--------------- 25 0,0 ------------------------------------------------------------GCGACCCAUACUUGGUUUCAGc-------------- 2 0,0 ------------------------------------------------------------GCGACCCAUACUUGGUUUCAGu-------------- 178 0,0 ------------------------------------------------------------GCGACCCAUACUUGGUUUCAGuu------------- 4 0,0 ------------------------------------------------------------GCGACCCAUACUUGGUUUCAGA-------------- 8 0,1 >hsa-mir-552 3pM:61-81 Tumor aaccauucaaauauaccacaguuuguuuaaccuuuugccuguugguugaagaugccuuucAACAGGUGACUGGUUAGACAAacugugguauauaca -----------------------UGUUUAACCUUUUGCCUGUU----------------------------------------------------- 3 -----------------------UGUUUAACCUUUUGCCUGUUG---------------------------------------------------- 13 -----------------------UGUUUAACCUUUUGCCUGUUGa--------------------------------------------------- 2 -----------------------UGUUUAACCUUUUGCCUGUUGG--------------------------------------------------- 42 -----------------------UGUUUAACCUUUUGCCUGUUGGa-------------------------------------------------- 3 -----------------------UGUUUAACCUUUUGCCUGUUGGU-------------------------------------------------- 25 ------------------------GUUUAACCUUUUGCCUGUUGGa-------------------------------------------------- 2 ------------------------------------------------------------AACAGGUGACUGGUUAGA------------------ 6 0,-3 ------------------------------------------------------------AACAGGUGACUGGUUAGAa----------------- 2 0,-3 ------------------------------------------------------------AACAGGUGACUGGUUAGAaa---------------- 3 0,-3 ------------------------------------------------------------AACAGGUGACUGGUUAGAC----------------- 8 0,-2 ------------------------------------------------------------AACAGGUGACUGGUUAGACu---------------- 3 0,-2 ------------------------------------------------------------AACAGGUGACUGGUUAGACA---------------- 53 0,-1 ------------------------------------------------------------AACAGGUGACUGGUUAGACAu--------------- 4 0,-1 ------------------------------------------------------------AACAGGUGACUGGUUAGACAA--------------- 43 0,0 ------------------------------------------------------------AACAGGUGACUGGUUAGACAAA-------------- 35 0,1 ------------------------------------------------------------AACAGGUGACUGGUUAGACAAAa------------- 3 0,1 >hsa-mir-556 5p:16-37;3p:55-76 Tumor gauaguaauaagaaaGAUGAGCUCAUUGUAAUAUGAGcuucauuuauacauuucAUAUUACCAUUAGCUCAUCUUUuuuauuacuaccuucaaca ---------------GAUGAGCUCAUUGUAAUAUG------------------------------------------------------------ 29 0,-2 ---------------GAUGAGCUCAUUGUAAUAUGA----------------------------------------------------------- 233 0,-1 ---------------GAUGAGCUCAUUGUAAUAUGAa---------------------------------------------------------- 8 0,-1 ------------------------------------------------------AUAUUACCAUUAGCUCAU----------------------- 2 0,-4 ------------------------------------------------------AUAUUACCAUUAGCUCAUC---------------------- 3 0,-3 ------------------------------------------------------AUAUUACCAUUAGCUCAUCU--------------------- 17 0,-2 ------------------------------------------------------AUAUUACCAUUAGCUCAUCUU-------------------- 41 0,-1 ------------------------------------------------------AUAUUACCAUUAGCUCAUCUUU------------------- 7 0,0 >hsa-mir-558 3pM:61-79 Tumor gugugugugugugugugugguuauuuugguauaguagcucuagacucuauuauaguuuccUGAGCUGCUGUACCAAAAUaccacaaacgggcug GUGUGUGUGUGUGUGUGUG--------------------------------------------------------------------------- 2 GUGUGUGUGUGUGUGUGUGu-------------------------------------------------------------------------- 2 -UGUGUGUGUGUGUGUGUG--------------------------------------------------------------------------- 2 >hsa-mir-559 5pM:16-36 Tumor gcuccaguaacaucuUAAAGUAAAUAUGCACCAAAAuuacuuuugguaaauacaguuuuggugcauauuuacuuuaggauguuacuggagcuccca ---------------UAAAGUAAAUAUGCACCAAAAU----------------------------------------------------------- 2 0,1 --------------------------------------------------------UUUGGUGCAUAUUUACUUUAGG------------------ 6 >hsa-mir-561 3pM:61-82 Tumor cuucauccaccaguccuccaggaacaucaaggaucuuaaacuuugccagagcuacaaaggCAAAGUUUAAGAUCCUUGAAGUuccugggggaaccau -------------------------AUCAAGGAUCUUAAACUUU----------------------------------------------------- 2 -------------------------AUCAAGGAUCUUAAACUUUG---------------------------------------------------- 2 -------------------------AUCAAGGAUCUUAAACUUUGa--------------------------------------------------- 2 -------------------------AUCAAGGAUCUUAAACUUUGC--------------------------------------------------- 10 -------------------------AUCAAGGAUCUUAAACUUUGCC-------------------------------------------------- 7 ------------------------------------------------------------CAAAGUUUAAGAUCCUUGAAGU--------------- 2 0,0 >hsa-mir-566 5pM:16-34 Tumor gcuaggcgugguggcGGGCGCCUGUGAUCCCAACuacucaggaggcuggggcagcagaaucgcuugaacccgggaggcgaagguugcagugagc -------------------------------------------------------AGAAUCGCUUGAACCCGGGAG------------------ 3 ---------------------------------------------------------AAUCGCUUGAACCCGGGAGGC---------------- 2 >hsa-mir-570 3pM:60-81 Tumor cuagauaaguuauuaggugggugcaaagguaauugcaguuuuucccauuauuuuaauugCGAAAACAGCAAUUACCUUUGCaccaaccugauggagu ------------------------AAAGGUAAUUGCAGUUUUUC----------------------------------------------------- 4 ------------------------AAAGGUAAUUGCAGUUUUUCC---------------------------------------------------- 15 ------------------------AAAGGUAAUUGCAGUUUUUCCC--------------------------------------------------- 6 ------------------------AAAGGUAAUUGCAGUUUUUCCCA-------------------------------------------------- 2 -----------------------------------------------------------CGAAAACAGCAAUUACCUUU------------------ 2 0,-2 -----------------------------------------------------------CGAAAACAGCAAUUACCUUUG----------------- 23 0,-1 -----------------------------------------------------------CGAAAACAGCAAUUACCUUUGC---------------- 58 0,0 >hsa-mir-574 5p:25-47;3p:61-82 Tumor gggaccugcgugggugcgggcgugUGAGUGUGUGUGUGUGAGUGUGUgucgcuccgggucCACGCUCAUGCACACACCCACAcgcccacacucagg -----------------------GUGAGUGUGUGUGUGUGAGU----------------------------------------------------- 3 -1,-4 -----------------------GUGAGUGUGUGUGUGUGAGUGU--------------------------------------------------- 8 -1,-2 -----------------------GUGAGUGUGUGUGUGUGAGUGUGU------------------------------------------------- 6 -1,0 ------------------------UGAGUGUGUGUGUGUGAG------------------------------------------------------ 27 0,-5 ------------------------UGAGUGUGUGUGUGUGAGa----------------------------------------------------- 17 0,-5 ------------------------UGAGUGUGUGUGUGUGAGaa---------------------------------------------------- 5 0,-5 ------------------------UGAGUGUGUGUGUGUGAGU----------------------------------------------------- 202 0,-4 ------------------------UGAGUGUGUGUGUGUGAGUa---------------------------------------------------- 4 0,-4 ------------------------UGAGUGUGUGUGUGUGAGUaa--------------------------------------------------- 6 0,-4 ------------------------UGAGUGUGUGUGUGUGAGUG---------------------------------------------------- 62 0,-3 ------------------------UGAGUGUGUGUGUGUGAGUGa--------------------------------------------------- 58 0,-3 ------------------------UGAGUGUGUGUGUGUGAGUGaa-------------------------------------------------- 13 0,-3 ------------------------UGAGUGUGUGUGUGUGAGUGau-------------------------------------------------- 5 0,-3 ------------------------UGAGUGUGUGUGUGUGAGUGg--------------------------------------------------- 3 0,-3 ------------------------UGAGUGUGUGUGUGUGAGUGU--------------------------------------------------- 1156 0,-2 ------------------------UGAGUGUGUGUGUGUGAGUGUa-------------------------------------------------- 11 0,-2 ------------------------UGAGUGUGUGUGUGUGAGUGUaa------------------------------------------------- 18 0,-2 ------------------------UGAGUGUGUGUGUGUGAGUGUau------------------------------------------------- 17 0,-2 ------------------------UGAGUGUGUGUGUGUGAGUGUu-------------------------------------------------- 26 0,-2 ------------------------UGAGUGUGUGUGUGUGAGUGUuu------------------------------------------------- 17 0,-2 ------------------------UGAGUGUGUGUGUGUGAGUGUG-------------------------------------------------- 269 0,-1 ------------------------UGAGUGUGUGUGUGUGAGUGUGa------------------------------------------------- 333 0,-1 ------------------------UGAGUGUGUGUGUGUGAGUGUGaa------------------------------------------------ 9 0,-1 ------------------------UGAGUGUGUGUGUGUGAGUGUGau------------------------------------------------ 8 0,-1 ------------------------UGAGUGUGUGUGUGUGAGUGUGU------------------------------------------------- 1591 0,0 ------------------------UGAGUGUGUGUGUGUGAGUGUGUa------------------------------------------------ 6 0,0 ------------------------UGAGUGUGUGUGUGUGAGUGUGUu------------------------------------------------ 25 0,0 ------------------------UGAGUGUGUGUGUGUGAGUGUGUuu----------------------------------------------- 7 0,0 ------------------------UGAGUGUGUGUGUGUGAGUGUGUG------------------------------------------------ 351 0,1 ------------------------UGAGUGUGUGUGUGUGAGUGUGUGa----------------------------------------------- 72 0,1 ------------------------UGAGUGUGUGUGUGUGAGUGUGUGU----------------------------------------------- 223 0,2 -------------------------GAGUGUGUGUGUGUGAGU----------------------------------------------------- 7 1,-4 -------------------------GAGUGUGUGUGUGUGAGUGU--------------------------------------------------- 38 1,-2 -------------------------GAGUGUGUGUGUGUGAGUGUG-------------------------------------------------- 2 1,-1 -------------------------GAGUGUGUGUGUGUGAGUGUGa------------------------------------------------- 2 1,-1 -------------------------GAGUGUGUGUGUGUGAGUGUGU------------------------------------------------- 31 1,0 -------------------------GAGUGUGUGUGUGUGAGUGUGUG------------------------------------------------ 2 1,1 ------------------------------------------------------------CACGCUCAUGCACACACC------------------ 15 0,-4 ------------------------------------------------------------CACGCUCAUGCACACACCu----------------- 2 0,-4 ------------------------------------------------------------CACGCUCAUGCACACACCC----------------- 108 0,-3 ------------------------------------------------------------CACGCUCAUGCACACACCCc---------------- 2 0,-3 ------------------------------------------------------------CACGCUCAUGCACACACCCu---------------- 2 0,-3 ------------------------------------------------------------CACGCUCAUGCACACACCCA---------------- 789 0,-2 ------------------------------------------------------------CACGCUCAUGCACACACCCAa--------------- 36 0,-2 ------------------------------------------------------------CACGCUCAUGCACACACCCAaa-------------- 12 0,-2 ------------------------------------------------------------CACGCUCAUGCACACACCCAu--------------- 73 0,-2 ------------------------------------------------------------CACGCUCAUGCACACACCCAuu-------------- 24 0,-2 ------------------------------------------------------------CACGCUCAUGCACACACCCAC--------------- 1045 0,-1 ------------------------------------------------------------CACGCUCAUGCACACACCCACc-------------- 95 0,-1 ------------------------------------------------------------CACGCUCAUGCACACACCCACg-------------- 2 0,-1 ------------------------------------------------------------CACGCUCAUGCACACACCCACu-------------- 273 0,-1 ------------------------------------------------------------CACGCUCAUGCACACACCCACA-------------- 6467 0,0 ------------------------------------------------------------CACGCUCAUGCACACACCCACAa------------- 132 0,0 ------------------------------------------------------------CACGCUCAUGCACACACCCACAaa------------ 5 0,0 ------------------------------------------------------------CACGCUCAUGCACACACCCACAau------------ 4 0,0 ------------------------------------------------------------CACGCUCAUGCACACACCCACAg------------- 2 0,0 ------------------------------------------------------------CACGCUCAUGCACACACCCACAu------------- 119 0,0 ------------------------------------------------------------CACGCUCAUGCACACACCCACAC------------- 3 0,1 -------------------------------------------------------------ACGCUCAUGCACACACCCA---------------- 21 1,-2 -------------------------------------------------------------ACGCUCAUGCACACACCCAC--------------- 20 1,-1 -------------------------------------------------------------ACGCUCAUGCACACACCCACc-------------- 4 1,-1 -------------------------------------------------------------ACGCUCAUGCACACACCCACA-------------- 252 1,0 -------------------------------------------------------------ACGCUCAUGCACACACCCACAa------------- 2 1,0 -------------------------------------------------------------ACGCUCAUGCACACACCCACAuu------------ 2 1,0 -------------------------------------------------------------ACGCUCAUGCACACACCCACAC------------- 4 1,1 -------------------------------------------------------------ACGCUCAUGCACACACCCACACu------------ 2 1,1 --------------------------------------------------------------CGCUCAUGCACACACCCACACu------------ 7 2,1 >hsa-mir-576 5p:16-37;3p:55-76 Tumor uacaauccaacgaggAUUCUAAUUUCUCCACGUCUUUgguaauaagguuuggcaAAGAUGUGGAAAAAUUGGAAUCcucauucgauugguuauaacca ---------------AUUCUAAUUUCUCCACGUCU--------------------------------------------------------------- 51 0,-2 ---------------AUUCUAAUUUCUCCACGUCUU-------------------------------------------------------------- 46 0,-1 ---------------AUUCUAAUUUCUCCACGUCUUU------------------------------------------------------------- 225 0,0 ---------------AUUCUAAUUUCUCCACGUCUUUG------------------------------------------------------------ 113 0,1 ---------------AUUCUAAUUUCUCCACGUCUUUGa----------------------------------------------------------- 4 0,1 ---------------AUUCUAAUUUCUCCACGUCUUUGu----------------------------------------------------------- 4 0,1 ------------------------------------------------------AAGAUGUGGAAAAAUUGGA------------------------- 14 0,-3 ------------------------------------------------------AAGAUGUGGAAAAAUUGGAA------------------------ 12 0,-2 ------------------------------------------------------AAGAUGUGGAAAAAUUGGAAa----------------------- 4 0,-2 ------------------------------------------------------AAGAUGUGGAAAAAUUGGAAU----------------------- 174 0,-1 ------------------------------------------------------AAGAUGUGGAAAAAUUGGAAUu---------------------- 2 0,-1 ------------------------------------------------------AAGAUGUGGAAAAAUUGGAAUC---------------------- 67 0,0 ------------------------------------------------------AAGAUGUGGAAAAAUUGGAAUCC--------------------- 78 0,1 -------------------------------------------------------AGAUGUGGAAAAAUUGGAAU----------------------- 2 1,-1 -------------------------------------------------------AGAUGUGGAAAAAUUGGAAUCu--------------------- 2 1,0 -------------------------------------------------------AGAUGUGGAAAAAUUGGAAUCC--------------------- 9 1,1 >hsa-mir-577 5pM:16-36 Tumor ugggggagugaagagUAGAUAAAAUAUUGGUACCUGaugaaucugaggccagguuucaauacuuuaucugcucuucauuuccccauaucuacuuac --------------GUAGAUAAAAUAUUGGUACC-------------------------------------------------------------- 2 -1,-2 --------------GUAGAUAAAAUAUUGGUACCU------------------------------------------------------------- 2 -1,-1 --------------GUAGAUAAAAUAUUGGUACCUG------------------------------------------------------------ 23 -1,0 --------------GUAGAUAAAAUAUUGGUACCUGu----------------------------------------------------------- 12 -1,0 ---------------UAGAUAAAAUAUUGGUACCUG------------------------------------------------------------ 2 0,0 ---------------UAGAUAAAAUAUUGGUACCUGA----------------------------------------------------------- 7 0,1 ----------------AGAUAAAAUAUUGGUACCUGAU---------------------------------------------------------- 4 1,2 >hsa-mir-579 3pM:62-84 Tumor cauauuagguuaaugcaaaaguaaucgcgguuugugccagaugacgauuugaauuaauaaaUUCAUUUGGUAUAAACCGCGAUUauuuuugcaucaac -----------------------AUCGCGGUUUGUGCCAGAUGAC----------------------------------------------------- 5 ------------------------UCGCGGUUUGUGCCAGAUGA------------------------------------------------------ 2 -------------------------------------------------------------UUCAUUUGGUAUAAACCGCGA---------------- 6 0,-2 -------------------------------------------------------------UUCAUUUGGUAUAAACCGCGAU--------------- 6 0,-1 -------------------------------------------------------------UUCAUUUGGUAUAAACCGCGAUU-------------- 41 0,0 >hsa-mir-580 3pM:61-82 Tumor auaaaauuuccaauuggaaccuaaugauucaucagacucagauauuuaaguuaacaguauUUGAGAAUGAUGAAUCAUUAGGuuccggucagaaauu ------------------------------------------------------------UUGAGAAUGAUGAAUCAUUAG---------------- 2 0,-1 ------------------------------------------------------------UUGAGAAUGAUGAAUCAUUAGG--------------- 4 0,0 >hsa-mir-582 5p:16-38;3p:53-74 Tumor aucugugcucuuugaUUACAGUUGUUCAACCAGUUACUaaucuaacuaauugUAACUGGUUGAACAACUGAACCcaaagggugcaaaguagaaacauu --------------AUUACAGUUGUUCAACCAGUU--------------------------------------------------------------- 7 -1,-3 ---------------UUACAGUUGUUCAACCAGU---------------------------------------------------------------- 17 0,-4 ---------------UUACAGUUGUUCAACCAGUU--------------------------------------------------------------- 134 0,-3 ---------------UUACAGUUGUUCAACCAGUUA-------------------------------------------------------------- 45 0,-2 ---------------UUACAGUUGUUCAACCAGUUAa------------------------------------------------------------- 2 0,-2 ---------------UUACAGUUGUUCAACCAGUUAau------------------------------------------------------------ 2 0,-2 ---------------UUACAGUUGUUCAACCAGUUAu------------------------------------------------------------- 3 0,-2 ---------------UUACAGUUGUUCAACCAGUUAC------------------------------------------------------------- 233 0,-1 ---------------UUACAGUUGUUCAACCAGUUACa------------------------------------------------------------ 2 0,-1 ---------------UUACAGUUGUUCAACCAGUUACU------------------------------------------------------------ 499 0,0 ----------------UACAGUUGUUCAACCAGUUAC------------------------------------------------------------- 20 1,-1 ----------------UACAGUUGUUCAACCAGUUACa------------------------------------------------------------ 2 1,-1 ----------------UACAGUUGUUCAACCAGUUACU------------------------------------------------------------ 152 1,0 -----------------ACAGUUGUUCAACCAGUUACU------------------------------------------------------------ 41 2,0 ----------------------------------------------------UAACUGGUUGAACAACUGA--------------------------- 25 0,-3 ----------------------------------------------------UAACUGGUUGAACAACUGAA-------------------------- 23 0,-2 ----------------------------------------------------UAACUGGUUGAACAACUGAAa------------------------- 8 0,-2 ----------------------------------------------------UAACUGGUUGAACAACUGAAC------------------------- 66 0,-1 ----------------------------------------------------UAACUGGUUGAACAACUGAACC------------------------ 19 0,0 ----------------------------------------------------UAACUGGUUGAACAACUGAACCC----------------------- 15 0,1 -----------------------------------------------------AACUGGUUGAACAACUGAAC------------------------- 4 1,-1 -----------------------------------------------------AACUGGUUGAACAACUGAACC------------------------ 2 1,0 -----------------------------------------------------AACUGGUUGAACAACUGAACCC----------------------- 2 1,1 >hsa-mir-584 5pM:16-37 Tumor uagggugaccagccaUUAUGGUUUGCCUGGGACUGAGgaauuugcugggauaugucaguuccaggccaaccaggcugguuggucucccugaagcaac ---------------UUAUGGUUUGCCUGGGACU--------------------------------------------------------------- 4 0,-3 ---------------UUAUGGUUUGCCUGGGACUGA------------------------------------------------------------- 41 0,-1 ---------------UUAUGGUUUGCCUGGGACUGAau----------------------------------------------------------- 2 0,-1 ---------------UUAUGGUUUGCCUGGGACUGAu------------------------------------------------------------ 3 0,-1 >hsa-mir-585 3pM:61-79 Tumor uggggugucugugcuauggcagcccuagcacacagauacgcccagagaaagccugaacguUGGGCGUAUCUGUAUGCUAgggcugcuguaacaa ------------------------CUAGCACACAGAUACGCCCAGA------------------------------------------------ 2 -----------------------------------------------------------UUGGGCGUAUCUGUAUGCUAGG------------- 2 -1,2 ------------------------------------------------------------UGGGCGUAUCUGUAUGCUAGG------------- 5 0,2 ------------------------------------------------------------UGGGCGUAUCUGUAUGCUAGGG------------ 12 0,3 ------------------------------------------------------------UGGGCGUAUCUGUAUGCUAGGGa----------- 5 0,3 >hsa-mir-587 5pM:16-36 Tumor cuccuaugcacccucUUUCCAUAGGUGAUGAGUCACagggcucagggaaugugucugcaccugugacucaucaccaguggaaagcccaucccauau ---------------UUUCCAUAGGUGAUGAGUCAC------------------------------------------------------------ 2 0,0 >hsa-mir-589 MA:24-45;mi:61-84 Tumor uccagccugugcccagcagccccUGAGAACCACGUCUGCUCUGAGcuggguacugccuguUCAGAACAAAUGCCGGUUCCCAGAcgcugccagcuggcc -----------------------UGAGAACCACGUCUGCUCUaa------------------------------------------------------- 2 0,-3 -----------------------UGAGAACCACGUCUGCUCUG-------------------------------------------------------- 4 0,-2 -----------------------UGAGAACCACGUCUGCUCUGA------------------------------------------------------- 350 0,-1 -----------------------UGAGAACCACGUCUGCUCUGAa------------------------------------------------------ 6 0,-1 -----------------------UGAGAACCACGUCUGCUCUGAu------------------------------------------------------ 2 0,-1 -----------------------UGAGAACCACGUCUGCUCUGAG------------------------------------------------------ 39 0,0 -----------------------UGAGAACCACGUCUGCUCUGAGa----------------------------------------------------- 9 0,0 -----------------------UGAGAACCACGUCUGCUCUGAGC----------------------------------------------------- 32 0,1 ------------------------GAGAACCACGUCUGCUCUGA------------------------------------------------------- 4 1,-1 ------------------------------------------------------------UCAGAACAAAUGCCGGUUCCCAG---------------- 4 0,-1 --------------------------------------------------------------AGAACAAAUGCCGGUUCCCAGA--------------- 6 2,0 >hsa-mir-590 5p:16-37;3p:56-76 Tumor uagccagucagaaauGAGCUUAUUCAUAAAAGUGCAGuauggugaagucaaucugUAAUUUUAUGUAUAAGCUAGUcucugauugaaacaugcagca --------------UGAGCUUAUUCAUAAAAGU---------------------------------------------------------------- 3 -1,-4 --------------UGAGCUUAUUCAUAAAAGUG--------------------------------------------------------------- 4 -1,-3 --------------UGAGCUUAUUCAUAAAAGUGC-------------------------------------------------------------- 19 -1,-2 --------------UGAGCUUAUUCAUAAAAGUGCA------------------------------------------------------------- 15 -1,-1 --------------UGAGCUUAUUCAUAAAAGUGCAG------------------------------------------------------------ 4 -1,0 ---------------GAGCUUAUUCAUAAAAGUG--------------------------------------------------------------- 22 0,-3 ---------------GAGCUUAUUCAUAAAAGUGa-------------------------------------------------------------- 11 0,-3 ---------------GAGCUUAUUCAUAAAAGUGC-------------------------------------------------------------- 36 0,-2 ---------------GAGCUUAUUCAUAAAAGUGCA------------------------------------------------------------- 143 0,-1 ---------------GAGCUUAUUCAUAAAAGUGCAa------------------------------------------------------------ 29 0,-1 ---------------GAGCUUAUUCAUAAAAGUGCAG------------------------------------------------------------ 2562 0,0 ---------------GAGCUUAUUCAUAAAAGUGCAGa----------------------------------------------------------- 27 0,0 ---------------GAGCUUAUUCAUAAAAGUGCAGU----------------------------------------------------------- 8 0,1 ---------------GAGCUUAUUCAUAAAAGUGCAGUA---------------------------------------------------------- 2 0,2 ----------------AGCUUAUUCAUAAAAGUGCAG------------------------------------------------------------ 7 1,0 ------------------------------------------------------GUAAUUUUAUGUAUAAGCU------------------------ 2 -1,-3 ------------------------------------------------------GUAAUUUUAUGUAUAAGCUAG---------------------- 55 -1,-1 ------------------------------------------------------GUAAUUUUAUGUAUAAGCUAGa--------------------- 4 -1,-1 ------------------------------------------------------GUAAUUUUAUGUAUAAGCUAGU--------------------- 562 -1,0 -------------------------------------------------------UAAUUUUAUGUAUAAGCUAG---------------------- 84 0,-1 -------------------------------------------------------UAAUUUUAUGUAUAAGCUAGa--------------------- 7 0,-1 -------------------------------------------------------UAAUUUUAUGUAUAAGCUAGU--------------------- 1188 0,0 -------------------------------------------------------UAAUUUUAUGUAUAAGCUAGUa-------------------- 42 0,0 -------------------------------------------------------UAAUUUUAUGUAUAAGCUAGUaa------------------- 16 0,0 -------------------------------------------------------UAAUUUUAUGUAUAAGCUAGUu-------------------- 16 0,0 -------------------------------------------------------UAAUUUUAUGUAUAAGCUAGUC-------------------- 230 0,1 -------------------------------------------------------UAAUUUUAUGUAUAAGCUAGUCa------------------- 19 0,1 -------------------------------------------------------UAAUUUUAUGUAUAAGCUAGUCg------------------- 2 0,1 --------------------------------------------------------AAUUUUAUGUAUAAGCUAGU--------------------- 25 1,0 >hsa-mir-592 5pM:16-37 Tumor uauuaugccaugacaUUGUGUCAAUAUGCGAUGAUGUguugugauggcacagcgucaucacguggugacgcaacaucaugacguaagacgucacaac ---------------UUGUGUCAAUAUGCGAUGAUu------------------------------------------------------------- 2 0,-2 ---------------UUGUGUCAAUAUGCGAUGAUG------------------------------------------------------------- 30 0,-1 ---------------UUGUGUCAAUAUGCGAUGAUGU------------------------------------------------------------ 190 0,0 ---------------UUGUGUCAAUAUGCGAUGAUGUa----------------------------------------------------------- 2 0,0 ---------------UUGUGUCAAUAUGCGAUGAUGUu----------------------------------------------------------- 4 0,0 ---------------UUGUGUCAAUAUGCGAUGAUGUGU---------------------------------------------------------- 2 0,2 >hsa-mir-597 5pM:16-37 Tumor uacuuacucuacgugUGUGUCACUCGAUGACCACUGUgaagacaguaaaauguacagugguucucuuguggcucaagcguaauguagaguacugguc ---------------UGUGUCACUCGAUGACCACUG------------------------------------------------------------- 4 0,-1 ---------------UGUGUCACUCGAUGACCACUGU------------------------------------------------------------ 74 0,0 >hsa-mir-598 3pM:61-82 Tumor gcuugaugaugcugcugaugcuggcggugaucccgauggugugagcuggaaauggggugcUACGUCAUCGUUGUCAUCGUCAucaucaucauccgag ------------------------------------------------------------UACGUCAUCGUUGUCAUCG------------------ 11 0,-3 ------------------------------------------------------------UACGUCAUCGUUGUCAUCGU----------------- 35 0,-2 ------------------------------------------------------------UACGUCAUCGUUGUCAUCGUC---------------- 49 0,-1 ------------------------------------------------------------UACGUCAUCGUUGUCAUCGUCA--------------- 319 0,0 ------------------------------------------------------------UACGUCAUCGUUGUCAUCGUCAa-------------- 2 0,0 ------------------------------------------------------------UACGUCAUCGUUGUCAUCGUCAU-------------- 18 0,1 -------------------------------------------------------------ACGUCAUCGUUGUCAUCGUCA--------------- 4 1,0 >hsa-mir-599 3pM:61-80 Tumor aaagacaugcuguccacaguguguuugauaagcugacaugggacagggauucuuuucacuGUUGUGUCAGUUUAUCAAACccauacuuggaugac ----------------------GUUUGAUAAGCUGACAUGGGAa--------------------------------------------------- 2 ----------------------GUUUGAUAAGCUGACAUGGGAC--------------------------------------------------- 4 -----------------------UUUGAUAAGCUGACAUGGGA---------------------------------------------------- 9 -----------------------UUUGAUAAGCUGACAUGGGAC--------------------------------------------------- 22 -----------------------UUUGAUAAGCUGACAUGGGACA-------------------------------------------------- 23 -----------------------UUUGAUAAGCUGACAUGGGACAG------------------------------------------------- 3 -----------------------UUUGAUAAGCUGACAUGGGACAGu------------------------------------------------ 7 >hsa-mir-600 3pM:61-83 Tumor aagucacgugcuguggcuccagcuucauaggaaggcucuugucugucaggcaguggaguuACUUACAGACAAGAGCCUUGCUCaggccagcccugccc -------------------------CAUAGGAAGGCUCUUGUCUG----------------------------------------------------- 2 >hsa-mir-602 5pM:16-38 Tumor uucucacccccgccuGACACGGGCGACAGCUGCGGCCCgcuguguucacucgggccgagugcgucuccugucaggcaagggagagcagagccccccug ---------------GACACGGGCGACAGCUGCGGCC------------------------------------------------------------- 2 0,-1 >hsa-mir-603 3pM:61-82 Tumor gauugaugcuguugguuuggugcaaaaguaauugcagugcuucccauuuaaaaguaauggCACACACUGCAAUUACUUUUGCuccaacuuaauacuu ----------------UUGGUGCAAAAGUAAUUGCu------------------------------------------------------------- 2 >hsa-mir-615 5p:18-39;3p:61-82 Tumor cucgggaggggcgggagGGGGGUCCCCGGUGCUCGGAUCucgagggugcuuauuguucggUCCGAGCCUGGGUCUCCCUCUUccccccaacccccc -----------------GGGGGUCCCCGGUGCUCGGAU---------------------------------------------------------- 3 0,-1 -----------------GGGGGUCCCCGGUGCUCGGAUC--------------------------------------------------------- 31 0,0 ------------------------------------------------------------UCCGAGCCUGGGUCUCCC------------------ 6 0,-4 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCa----------------- 4 0,-4 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCaa---------------- 2 0,-4 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCU----------------- 131 0,-3 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUa---------------- 8 0,-3 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUaa--------------- 8 0,-3 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUau--------------- 4 0,-3 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUu---------------- 18 0,-3 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUuu--------------- 18 0,-3 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUC---------------- 64 0,-2 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUCa--------------- 7 0,-2 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUCc--------------- 2 0,-2 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUCU--------------- 640 0,-1 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUCUa-------------- 2 0,-1 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUCUaa------------- 9 0,-1 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUCUau------------- 2 0,-1 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUCUU-------------- 356 0,0 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUCUUa------------- 21 0,0 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUCUUg------------- 2 0,0 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUCUUu------------- 106 0,0 ------------------------------------------------------------UCCGAGCCUGGGUCUCCCUCUUuu------------ 17 0,0 -------------------------------------------------------------CCGAGCCUGGGUCUCCCUCUU-------------- 2 1,0 --------------------------------------------------------------CGAGCCUGGGUCUCCCUCU--------------- 4 2,-1 >hsa-mir-616 mi:16-37;MA:56-77 Tumor uuagguaauuccuccACUCAAAACCCUUCAGUGACUUccaugacaugaaauaggaAGUCAUUGGAGGGUUUGAGCAGaggaaugaccuguuuuaaaa ---------------ACUCAAAACCCUUCAGUGACU------------------------------------------------------------- 25 0,-1 ---------------ACUCAAAACCCUUCAGUGACUU------------------------------------------------------------ 15 0,0 ---------------ACUCAAAACCCUUCAGUGACUUC----------------------------------------------------------- 2 0,1 ------------------------------------------------------AAGUCAUUGGAGGGUUUGAGCAG-------------------- 2 -1,0 >hsa-mir-618 5pM:16-38 Tumor cucuuguucacagccAAACUCUACUUGUCCUUCUGAGUguaauuacguacaugcaguagcucaggagacaagcagguuuacccuguggaugagucuga ---------------AAACUCUACUUGUCCUUCUG--------------------------------------------------------------- 4 0,-3 ---------------AAACUCUACUUGUCCUUCUGA-------------------------------------------------------------- 28 0,-2 ---------------AAACUCUACUUGUCCUUCUGAa------------------------------------------------------------- 2 0,-2 ---------------AAACUCUACUUGUCCUUCUGAaa------------------------------------------------------------ 2 0,-2 ---------------AAACUCUACUUGUCCUUCUGAG------------------------------------------------------------- 76 0,-1 ---------------AAACUCUACUUGUCCUUCUGAGa------------------------------------------------------------ 38 0,-1 ---------------AAACUCUACUUGUCCUUCUGAGU------------------------------------------------------------ 246 0,0 ----------------AACUCUACUUGUCCUUCUGAGa------------------------------------------------------------ 2 1,-1 ----------------AACUCUACUUGUCCUUCUGAGU------------------------------------------------------------ 6 1,0 >hsa-mir-619 3pM:61-84 Tumor cgcccaccucagccucccaaaaugcugggauuacaggcaugagccacugcggucgaccauGACCUGGACAUGUUUGUGCCCAGUacugucaguuugcag ----------------------UGCUGGGAUUACAGGCAUGAGCC------------------------------------------------------ 3 -----------------------GCUGGGAUUACAGGCAUG---------------------------------------------------------- 2 ------------------------CUGGGAUUACAGGCAUGAGCC------------------------------------------------------ 3 ------------------------CUGGGAUUACAGGCAUGAGCCACc--------------------------------------------------- 2 -------------------------UGGGAUUACAGGCAUGAGC------------------------------------------------------- 8 -------------------------UGGGAUUACAGGCAUGAGCC------------------------------------------------------ 6 -------------------------UGGGAUUACAGGCAUGAGCCA----------------------------------------------------- 2 -------------------------UGGGAUUACAGGCAUGAGCCAC---------------------------------------------------- 2 -------------------------UGGGAUUACAGGCAUGAGCCACU--------------------------------------------------- 2 --------------------------GGGAUUACAGGCAUGAGCCACc--------------------------------------------------- 4 --------------------------GGGAUUACAGGCAUGAGCCACU--------------------------------------------------- 2 >hsa-mir-622 3pM:61-81 Tumor agagaagcuggacaaguacuggucucagcagauugaggagagcaccacaguggucaucacACAGUCUGCUGAGGUUGGAGCugcugagaugacacu ------------------------------------------------------------ACAGUCUGCUGAGGUUGGAGC--------------- 2 0,0 >hsa-mir-624 mi:16-37;MA:54-74 Tumor aaugcuguuucaaggUAGUACCAGUACCUUGUGUUCAguggaaccaagguaaaCACAAGGUAUUGGUAUUACCUugagauagcauuacaccuaagug --------------GUAGUACCAGUACCUUGUGUU-------------------------------------------------------------- 2 -1,-2 ---------------UAGUACCAGUACCUUGUGU--------------------------------------------------------------- 2 0,-3 ---------------UAGUACCAGUACCUUGUGUU-------------------------------------------------------------- 14 0,-2 ---------------UAGUACCAGUACCUUGUGUUC------------------------------------------------------------- 21 0,-1 ---------------UAGUACCAGUACCUUGUGUUCA------------------------------------------------------------ 20 0,0 ----------------AGUACCAGUACCUUGUGUUCA------------------------------------------------------------ 2 1,0 ---------------------------------------------------AACACAAGGUAUUGGUAUUAC------------------------- 5 -2,-2 -----------------------------------------------------CACAAGGUAUUGGUAUUACCU----------------------- 2 0,0 >hsa-mir-625 MA:15-35;mi:52-73 Tumor aggguagagggaugAGGGGGAAAGUUCUAUAGUCCuguaauuagaucucagGACUAUAGAACUUUCCCCCUCAucccucugcccu --------------AGGGGGAAAGUUCUAUAGa---------------------------------------------------- 3 0,-3 --------------AGGGGGAAAGUUCUAUAGU---------------------------------------------------- 139 0,-2 --------------AGGGGGAAAGUUCUAUAGUC--------------------------------------------------- 240 0,-1 --------------AGGGGGAAAGUUCUAUAGUCa-------------------------------------------------- 54 0,-1 --------------AGGGGGAAAGUUCUAUAGUCu-------------------------------------------------- 4 0,-1 --------------AGGGGGAAAGUUCUAUAGUCC-------------------------------------------------- 372 0,0 --------------AGGGGGAAAGUUCUAUAGUCCa------------------------------------------------- 2 0,0 --------------AGGGGGAAAGUUCUAUAGUCCU------------------------------------------------- 671 0,1 --------------AGGGGGAAAGUUCUAUAGUCCUa------------------------------------------------ 2 0,1 --------------AGGGGGAAAGUUCUAUAGUCCUu------------------------------------------------ 10 0,1 ---------------GGGGGAAAGUUCUAUAGU---------------------------------------------------- 2 1,-2 ---------------GGGGGAAAGUUCUAUAGUC--------------------------------------------------- 3 1,-1 ---------------GGGGGAAAGUUCUAUAGUCC-------------------------------------------------- 8 1,0 ---------------GGGGGAAAGUUCUAUAGUCCU------------------------------------------------- 4 1,1 ---------------------------------------------------GACUAUAGAACUUUCCCCC--------------- 2 0,-3 ---------------------------------------------------GACUAUAGAACUUUCCCCCU-------------- 114 0,-2 ---------------------------------------------------GACUAUAGAACUUUCCCCCUa------------- 4 0,-2 ---------------------------------------------------GACUAUAGAACUUUCCCCCUu------------- 5 0,-2 ---------------------------------------------------GACUAUAGAACUUUCCCCCUuu------------ 6 0,-2 ---------------------------------------------------GACUAUAGAACUUUCCCCCUC------------- 127 0,-1 ---------------------------------------------------GACUAUAGAACUUUCCCCCUCc------------ 2 0,-1 ---------------------------------------------------GACUAUAGAACUUUCCCCCUCu------------ 94 0,-1 ---------------------------------------------------GACUAUAGAACUUUCCCCCUCA------------ 524 0,0 ---------------------------------------------------GACUAUAGAACUUUCCCCCUCAa----------- 20 0,0 ---------------------------------------------------GACUAUAGAACUUUCCCCCUCAaa---------- 2 0,0 ---------------------------------------------------GACUAUAGAACUUUCCCCCUCAau---------- 2 0,0 ---------------------------------------------------GACUAUAGAACUUUCCCCCUCAU----------- 27 0,1 ---------------------------------------------------GACUAUAGAACUUUCCCCCUCAUu---------- 2 0,1 ----------------------------------------------------ACUAUAGAACUUUCCCCCUC------------- 5 1,-1 ----------------------------------------------------ACUAUAGAACUUUCCCCCUCu------------ 2 1,-1 ----------------------------------------------------ACUAUAGAACUUUCCCCCUCA------------ 46 1,0 ----------------------------------------------------ACUAUAGAACUUUCCCCCUCAa----------- 5 1,0 >hsa-mir-627 5pM:16-37 Tumor uacuuauuacugguaGUGAGUCUCUAAGAAAAGAGGAggugguuguuuuccuccucuuuucuuugagacucacuaccaauaauaagaaauacuacua ---------------GUGAGUCUCUAAGAAAAGAGaa------------------------------------------------------------ 2 0,-2 ---------------GUGAGUCUCUAAGAAAAGAGG------------------------------------------------------------- 22 0,-1 ---------------GUGAGUCUCUAAGAAAAGAGGA------------------------------------------------------------ 163 0,0 ---------------GUGAGUCUCUAAGAAAAGAGGAa----------------------------------------------------------- 2 0,0 ---------------GUGAGUCUCUAAGAAAAGAGGAu----------------------------------------------------------- 2 0,0 ----------------UGAGUCUCUAAGAAAAGA--------------------------------------------------------------- 2 1,-3 ----------------UGAGUCUCUAAGAAAAGAGGA------------------------------------------------------------ 17 1,0 ----------------UGAGUCUCUAAGAAAAGAGGAG----------------------------------------------------------- 114 1,1 ----------------UGAGUCUCUAAGAAAAGAGGAGa---------------------------------------------------------- 5 1,1 ----------------UGAGUCUCUAAGAAAAGAGGAGu---------------------------------------------------------- 14 1,1 ----------------UGAGUCUCUAAGAAAAGAGGAGG---------------------------------------------------------- 7 1,2 -----------------GAGUCUCUAAGAAAAGAGG------------------------------------------------------------- 2 2,-1 ----------------------------------------------------CCUCUUUUCUUUGAGACUCACU----------------------- 4 -----------------------------------------------------CUCUUUUCUUUGAGACUCACU----------------------- 13 -----------------------------------------------------CUCUUUUCUUUGAGACUCACUA---------------------- 2 ------------------------------------------------------UCUUUUCUUUGAGACUCACU----------------------- 4 >hsa-mir-628 5p:23-44;3p:61-81 Tumor auagcuguugugucacuuccucAUGCUGACAUAUUUACUAGAGGguaaaauuaauaaccuUCUAGUAAGAGUGGCAGUCGAagggaagggcucau ----------------------AUGCUGACAUAUUUACUAGA----------------------------------------------------- 17 0,-2 ----------------------AUGCUGACAUAUUUACUAGAG---------------------------------------------------- 82 0,-1 ----------------------AUGCUGACAUAUUUACUAGAGa--------------------------------------------------- 9 0,-1 ----------------------AUGCUGACAUAUUUACUAGAGG--------------------------------------------------- 270 0,0 ----------------------AUGCUGACAUAUUUACUAGAGGa-------------------------------------------------- 19 0,0 ----------------------AUGCUGACAUAUUUACUAGAGGu-------------------------------------------------- 3 0,0 ----------------------AUGCUGACAUAUUUACUAGAGGG-------------------------------------------------- 6 0,1 ----------------------AUGCUGACAUAUUUACUAGAGGGU------------------------------------------------- 11 0,2 >hsa-mir-629 MA:22-42;mi:61-82 Tumor ucccuuucccaggggaggggcUGGGUUUACGUUGGGAGAACUuuuacggugaaccaggagGUUCUCCCAACGUAAGCCCAGCcccuccccucugccu --------------------CUGGGUUUACGUUGGGAGAACU------------------------------------------------------- 4 -1,0 ---------------------UGGGUUUACGUUGGGAGA---------------------------------------------------------- 14 0,-3 ---------------------UGGGUUUACGUUGGGAGAA--------------------------------------------------------- 22 0,-2 ---------------------UGGGUUUACGUUGGGAGAAa-------------------------------------------------------- 21 0,-2 ---------------------UGGGUUUACGUUGGGAGAAu-------------------------------------------------------- 14 0,-2 ---------------------UGGGUUUACGUUGGGAGAAuu------------------------------------------------------- 2 0,-2 ---------------------UGGGUUUACGUUGGGAGAAC-------------------------------------------------------- 237 0,-1 ---------------------UGGGUUUACGUUGGGAGAACa------------------------------------------------------- 2 0,-1 ---------------------UGGGUUUACGUUGGGAGAACU------------------------------------------------------- 1045 0,0 ---------------------UGGGUUUACGUUGGGAGAACUaa----------------------------------------------------- 4 0,0 ---------------------UGGGUUUACGUUGGGAGAACUg------------------------------------------------------ 2 0,0 ---------------------UGGGUUUACGUUGGGAGAACUU------------------------------------------------------ 1502 0,1 ---------------------UGGGUUUACGUUGGGAGAACUUa----------------------------------------------------- 73 0,1 ---------------------UGGGUUUACGUUGGGAGAACUUaa---------------------------------------------------- 2 0,1 ---------------------UGGGUUUACGUUGGGAGAACUUg----------------------------------------------------- 2 0,1 ---------------------UGGGUUUACGUUGGGAGAACUUU----------------------------------------------------- 162 0,2 ---------------------UGGGUUUACGUUGGGAGAACUUUU---------------------------------------------------- 3 0,3 ----------------------GGGUUUACGUUGGGAGAAC-------------------------------------------------------- 4 1,-1 ----------------------GGGUUUACGUUGGGAGAACU------------------------------------------------------- 17 1,0 ----------------------GGGUUUACGUUGGGAGAACUU------------------------------------------------------ 44 1,1 ----------------------GGGUUUACGUUGGGAGAACUUU----------------------------------------------------- 3 1,2 ------------------------------------------------------------GUUCUCCCAACGUAAGCCCAG---------------- 6 0,-1 ------------------------------------------------------------GUUCUCCCAACGUAAGCCCAGa--------------- 4 0,-1 ------------------------------------------------------------GUUCUCCCAACGUAAGCCCAGu--------------- 20 0,-1 ------------------------------------------------------------GUUCUCCCAACGUAAGCCCAGC--------------- 70 0,0 -------------------------------------------------------------UUCUCCCAACGUAAGCCCAGa--------------- 2 1,-1 -------------------------------------------------------------UUCUCCCAACGUAAGCCCAGu--------------- 4 1,-1 -------------------------------------------------------------UUCUCCCAACGUAAGCCCAGC--------------- 12 1,0 -------------------------------------------------------------UUCUCCCAACGUAAGCCCAGCC-------------- 2 1,1 -------------------------------------------------------------UUCUCCCAACGUAAGCCCAGCCau------------ 2 1,1 >hsa-mir-641 5pM:16-39 Tumor ugggugaaaggaaggAAAGACAUAGGAUAGAGUCACCUCuguccucuguccucuaccuauagaggugacuguccuaugucuuuccuuccucuuaccccu --------------GAAAGACAUAGGAUAGAGUCA---------------------------------------------------------------- 2 -1,-4 ---------------AAAGACAUAGGAUAGAGUCA---------------------------------------------------------------- 5 0,-4 ---------------AAAGACAUAGGAUAGAGUCAC--------------------------------------------------------------- 6 0,-3 ---------------AAAGACAUAGGAUAGAGUCACC-------------------------------------------------------------- 4 0,-2 ---------------AAAGACAUAGGAUAGAGUCACCU------------------------------------------------------------- 20 0,-1 ---------------AAAGACAUAGGAUAGAGUCACCUC------------------------------------------------------------ 6 0,0 >hsa-mir-642a 5pM:16-37 Tumor aucugaguugggaggGUCCCUCUCCAAAUGUGUCUUGgggugggggaucaagacacauuuggagagggaaccucccaacucggccucugccaucauu ---------------GUCCCUCUCCAAAUGUGUC--------------------------------------------------------------- 2 0,-3 ---------------GUCCCUCUCCAAAUGUGUCU-------------------------------------------------------------- 6 0,-2 ---------------GUCCCUCUCCAAAUGUGUCUUG------------------------------------------------------------ 14 0,0 ---------------GUCCCUCUCCAAAUGUGUCUUGu----------------------------------------------------------- 2 0,0 --------------------------------------------------AGACACAUUUGGAGAGGGA---------------------------- 2 --------------------------------------------------AGACACAUUUGGAGAGGGAA--------------------------- 4 --------------------------------------------------AGACACAUUUGGAGAGGGAAC-------------------------- 19 --------------------------------------------------AGACACAUUUGGAGAGGGAACC------------------------- 4 >hsa-mir-642b 3pM:47-68 Tumor gaguugggagguucccucuccaaaugugucuugaucccccaccccaAGACACAUUUGGAGAGGGACCCucccaacuc ----------------------------------------------AGACACAUUUGGAGAGGGA------------ 2 0,-3 >hsa-mir-643 3pM:61-82 Tumor accaagugauauucauugucuaccugagcuagaauacaaguaguuggcgucuucagagacACUUGUAUGCUAGCUCAGGUAGauauugaaugaaaaa ----------------------------------------------------------ACACUUGUAUGCUAGCUCAGa------------------ 2 -2,-4 ----------------------------------------------------------ACACUUGUAUGCUAGCUCAGG------------------ 4 -2,-3 ----------------------------------------------------------ACACUUGUAUGCUAGCUCAGGU----------------- 23 -2,-2 ------------------------------------------------------------ACUUGUAUGCUAGCUCAGGUAG--------------- 4 0,0 >hsa-mir-651 5pM:16-37 Tumor aaucuaucacugcuuUUUAGGAUAAGCUUGACUUUUGuucaaauaaaaaugcaaaaggaaaguguauccuaaaaggcaaugacaguuuaauguguuu --------------UUUUAGGAUAAGCUUGACUUU-------------------------------------------------------------- 2 -1,-2 ---------------UUUAGGAUAAGCUUGACUUU-------------------------------------------------------------- 62 0,-2 ---------------UUUAGGAUAAGCUUGACUUUU------------------------------------------------------------- 278 0,-1 ---------------UUUAGGAUAAGCUUGACUUUUG------------------------------------------------------------ 377 0,0 ---------------UUUAGGAUAAGCUUGACUUUUGa----------------------------------------------------------- 25 0,0 ---------------UUUAGGAUAAGCUUGACUUUUGau---------------------------------------------------------- 2 0,0 ---------------UUUAGGAUAAGCUUGACUUUUGU----------------------------------------------------------- 9 0,1 ----------------UUAGGAUAAGCUUGACUUUU------------------------------------------------------------- 2 1,-1 ----------------UUAGGAUAAGCUUGACUUUUG------------------------------------------------------------ 3 1,0 ----------------UUAGGAUAAGCUUGACUUUUGU----------------------------------------------------------- 5 1,1 >hsa-mir-652 3pM:61-81 Tumor acgaauggcuaugcacugcacaacccuaggagagggugccauucacauagacuauaauugAAUGGCGCCACUAGGGUUGUGcagugcacaaccuacac -------------------ACAACCCUAGGAGAGGGU------------------------------------------------------------- 2 -------------------ACAACCCUAGGAGAGGGUG------------------------------------------------------------ 15 -------------------ACAACCCUAGGAGAGGGUGC----------------------------------------------------------- 43 -------------------ACAACCCUAGGAGAGGGUGCC---------------------------------------------------------- 14 -------------------ACAACCCUAGGAGAGGGUGCCu--------------------------------------------------------- 2 -------------------ACAACCCUAGGAGAGGGUGCCA--------------------------------------------------------- 56 -------------------ACAACCCUAGGAGAGGGUGCCAau------------------------------------------------------- 2 -------------------ACAACCCUAGGAGAGGGUGCCAU-------------------------------------------------------- 43 -------------------ACAACCCUAGGAGAGGGUGCCAUU------------------------------------------------------- 76 -------------------ACAACCCUAGGAGAGGGUGCCAUUC------------------------------------------------------ 11 --------------------CAACCCUAGGAGAGGGUGCCAU-------------------------------------------------------- 3 --------------------CAACCCUAGGAGAGGGUGCCAUU------------------------------------------------------- 11 --------------------CAACCCUAGGAGAGGGUGCCAUUCA----------------------------------------------------- 2 -----------------------------------------------------------GAAUGGCGCCACUAGGGUUGUGu---------------- 3 -1,0 ------------------------------------------------------------AAUGGCGCCACUAGGGUU-------------------- 13 0,-3 ------------------------------------------------------------AAUGGCGCCACUAGGGUUG------------------- 82 0,-2 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGa------------------ 3 0,-2 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGU------------------ 1021 0,-1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUa----------------- 20 0,-1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUaa---------------- 21 0,-1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUau---------------- 13 0,-1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUu----------------- 80 0,-1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUuu---------------- 76 0,-1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUG----------------- 1463 0,0 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGa---------------- 1722 0,0 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGaa--------------- 154 0,0 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGau--------------- 27 0,0 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGg---------------- 4 0,0 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGu---------------- 4974 0,0 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGuu--------------- 217 0,0 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGC---------------- 1083 0,1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGCu--------------- 184 0,1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGCuu-------------- 6 0,1 ------------------------------------------------------------AAUGGCGCCACUAGGGUUGUGCA--------------- 38 0,2 -------------------------------------------------------------AUGGCGCCACUAGGGUUGU------------------ 10 1,-1 -------------------------------------------------------------AUGGCGCCACUAGGGUUGUG----------------- 13 1,0 -------------------------------------------------------------AUGGCGCCACUAGGGUUGUGa---------------- 22 1,0 -------------------------------------------------------------AUGGCGCCACUAGGGUUGUGu---------------- 85 1,0 -------------------------------------------------------------AUGGCGCCACUAGGGUUGUGuu--------------- 2 1,0 -------------------------------------------------------------AUGGCGCCACUAGGGUUGUGC---------------- 19 1,1 -------------------------------------------------------------AUGGCGCCACUAGGGUUGUGCu--------------- 2 1,1 >hsa-mir-653 5pM:13-33 Tumor uucauuccuucaGUGUUGAAACAAUCUCUACUGaaccagcuucaaacaaguucacuggaguuuguuucaauauugcaagaaugauaagauggaagc -------------UGUUGAAACAAUCUCUACUGA-------------------------------------------------------------- 2 1,1 --------------------------------------------------UUCACUGGAGUUUGUUUCA--------------------------- 10 --------------------------------------------------UUCACUGGAGUUUGUUUCAu-------------------------- 2 --------------------------------------------------UUCACUGGAGUUUGUUUCAA-------------------------- 4 --------------------------------------------------UUCACUGGAGUUUGUUUCAAU------------------------- 71 --------------------------------------------------UUCACUGGAGUUUGUUUCAAUA------------------------ 35 -----------------------------------------------------ACUGGAGUUUGUUUCAAUAUU---------------------- 4 -----------------------------------------------------ACUGGAGUUUGUUUCAAUAUUG--------------------- 4 -----------------------------------------------------ACUGGAGUUUGUUUCAAUAUUGa-------------------- 2 >hsa-mir-654 5p:16-37;3p:51-72 Tumor ggguaaguggaaagaUGGUGGGCCGCAGAACAUGUGCugaguucgugccaUAUGUCUGCUGACCAUCACCUUuagaagccc --------------AUGGUGGGCCGCAGAACAUGU---------------------------------------------- 5 -1,-2 ---------------UGGUGGGCCGCAGAACAUGUG--------------------------------------------- 6 0,-1 ---------------UGGUGGGCCGCAGAACAUGUGC-------------------------------------------- 21 0,0 ------------------------------------------------CAUAUGUCUGCUGACCAUCACu----------- 10 -2,-3 ------------------------------------------------CAUAUGUCUGCUGACCAUCACC----------- 10 -2,-2 -------------------------------------------------AUAUGUCUGCUGACCAUCACu----------- 4 -1,-3 -------------------------------------------------AUAUGUCUGCUGACCAUCACC----------- 4 -1,-2 --------------------------------------------------UAUGUCUGCUGACCAUCAC------------ 15 0,-3 --------------------------------------------------UAUGUCUGCUGACCAUCACa----------- 9 0,-3 --------------------------------------------------UAUGUCUGCUGACCAUCACaa---------- 2 0,-3 --------------------------------------------------UAUGUCUGCUGACCAUCACu----------- 14 0,-3 --------------------------------------------------UAUGUCUGCUGACCAUCACuu---------- 9 0,-3 --------------------------------------------------UAUGUCUGCUGACCAUCACC----------- 197 0,-2 --------------------------------------------------UAUGUCUGCUGACCAUCACCa---------- 49 0,-2 --------------------------------------------------UAUGUCUGCUGACCAUCACCaa--------- 2 0,-2 --------------------------------------------------UAUGUCUGCUGACCAUCACCau--------- 10 0,-2 --------------------------------------------------UAUGUCUGCUGACCAUCACCU---------- 124 0,-1 --------------------------------------------------UAUGUCUGCUGACCAUCACCUa--------- 6 0,-1 --------------------------------------------------UAUGUCUGCUGACCAUCACCUau-------- 4 0,-1 --------------------------------------------------UAUGUCUGCUGACCAUCACCUU--------- 6 0,0 --------------------------------------------------UAUGUCUGCUGACCAUCACCUUU-------- 4 0,1 --------------------------------------------------UAUGUCUGCUGACCAUCACCUUUu------- 2 0,1 ---------------------------------------------------AUGUCUGCUGACCAUCAC------------ 2 1,-3 >hsa-mir-655 3pM:61-82 Tumor aacuaugcaaggauauuugaggagagguuauccguguuauguucgcuucauucaucaugaAUAAUACAUGGUUAACCUCUUUuugaauaucagacuc ----------------------AGAGGUUAUCCGUGUUAUGUU------------------------------------------------------ 2 ------------------------------------------------------------AUAAUACAUGGUUAACCUC------------------ 3 0,-3 ------------------------------------------------------------AUAAUACAUGGUUAACCUCU----------------- 18 0,-2 ------------------------------------------------------------AUAAUACAUGGUUAACCUCUU---------------- 40 0,-1 ------------------------------------------------------------AUAAUACAUGGUUAACCUCUUa--------------- 5 0,-1 ------------------------------------------------------------AUAAUACAUGGUUAACCUCUUU--------------- 536 0,0 ------------------------------------------------------------AUAAUACAUGGUUAACCUCUUUa-------------- 5 0,0 ------------------------------------------------------------AUAAUACAUGGUUAACCUCUUUU-------------- 15 0,1 >hsa-mir-656 3pM:43-63 Tumor cugaaauagguugccugugagguguucacuuucuauaugaugAAUAUUAUACAGUCAACCUCUuuccgauaucgaauc -------AGGUUGCCUGUGAGGUGUUC--------------------------------------------------- 2 -------AGGUUGCCUGUGAGGUGUUCA-------------------------------------------------- 2 ------------------------------------------AAUAUUAUACAGUCAACCUCc--------------- 2 0,-1 ------------------------------------------AAUAUUAUACAGUCAACCUCU--------------- 206 0,0 -------------------------------------------AUAUUAUACAGUCAACCUCU--------------- 5 1,0 >hsa-mir-659 3pM:61-82 Tumor uaccgacccucgauuugguucaggaccuucccugaaccaaggaagagucacagucucuucCUUGGUUCAGGGAGGGUCCCCAacaauguccucaugg ---------------------AGGACCUUCCCUGAACCAAGGA------------------------------------------------------ 2 >hsa-mir-660 5pM:16-37 Tumor cugcuccuucucccaUACCCAUUGCAUAUCGGAGUUGugaauucucaaaacaccuccugugugcauggauuacaggagggugagccuugucaucgug ---------------UACCCAUUGCAUAUCGGA---------------------------------------------------------------- 5 0,-4 ---------------UACCCAUUGCAUAUCGGAG--------------------------------------------------------------- 6 0,-3 ---------------UACCCAUUGCAUAUCGGAGU-------------------------------------------------------------- 22 0,-2 ---------------UACCCAUUGCAUAUCGGAGUU------------------------------------------------------------- 132 0,-1 ---------------UACCCAUUGCAUAUCGGAGUUa------------------------------------------------------------ 8 0,-1 ---------------UACCCAUUGCAUAUCGGAGUUau----------------------------------------------------------- 2 0,-1 ---------------UACCCAUUGCAUAUCGGAGUUu------------------------------------------------------------ 4 0,-1 ---------------UACCCAUUGCAUAUCGGAGUUuu----------------------------------------------------------- 2 0,-1 ---------------UACCCAUUGCAUAUCGGAGUUG------------------------------------------------------------ 1923 0,0 ---------------UACCCAUUGCAUAUCGGAGUUGa----------------------------------------------------------- 303 0,0 ---------------UACCCAUUGCAUAUCGGAGUUGc----------------------------------------------------------- 2 0,0 ---------------UACCCAUUGCAUAUCGGAGUUGU----------------------------------------------------------- 3813 0,1 ---------------UACCCAUUGCAUAUCGGAGUUGUa---------------------------------------------------------- 9 0,1 ---------------UACCCAUUGCAUAUCGGAGUUGUu---------------------------------------------------------- 4 0,1 ---------------UACCCAUUGCAUAUCGGAGUUGUG---------------------------------------------------------- 6 0,2 ---------------UACCCAUUGCAUAUCGGAGUUGUGA--------------------------------------------------------- 2 0,3 ----------------ACCCAUUGCAUAUCGGAGUU------------------------------------------------------------- 2 1,-1 ----------------ACCCAUUGCAUAUCGGAGUUG------------------------------------------------------------ 64 1,0 ----------------ACCCAUUGCAUAUCGGAGUUGa----------------------------------------------------------- 2 1,0 ----------------ACCCAUUGCAUAUCGGAGUUGU----------------------------------------------------------- 156 1,1 ---------------------------------------------------ACCUCCUGUGUGCAUGGAau-------------------------- 2 ---------------------------------------------------ACCUCCUGUGUGCAUGGAU--------------------------- 14 ---------------------------------------------------ACCUCCUGUGUGCAUGGAUU-------------------------- 103 ---------------------------------------------------ACCUCCUGUGUGCAUGGAUUA------------------------- 5 ---------------------------------------------------ACCUCCUGUGUGCAUGGAUUAC------------------------ 26 ---------------------------------------------------ACCUCCUGUGUGCAUGGAUUACA----------------------- 6 >hsa-mir-663b 3pM:90-111 Tumor ggugccgagggccguccggcauccuaggcgggucgcugcgguaccucccuccugucuguggcggugggaucccguggccguguuuuccuGGUGGCCCGGCCGUGCCUGAGGuuuc -----------------------------------------------------------------------------------------GGUGGCCCGGCCGUGCCUGAGG---- 8 0,0 >hsa-mir-664 mi:11-34;MA:49-71 Tumor gaacauugaaACUGGCUAGGGAAAAUGAUUGGAUagaaacuauuauucUAUUCAUUUAUCCCCAGCCUACAaaaugaaaaaa ----------ACUGGCUAGGGAAAAUGAUU---------------------------------------------------- 6 0,-4 ----------ACUGGCUAGGGAAAAUGAUUG--------------------------------------------------- 4 0,-3 ----------ACUGGCUAGGGAAAAUGAUUGG-------------------------------------------------- 274 0,-2 ----------ACUGGCUAGGGAAAAUGAUUGGA------------------------------------------------- 139 0,-1 ----------ACUGGCUAGGGAAAAUGAUUGGAa------------------------------------------------ 2 0,-1 -----------CUGGCUAGGGAAAAUGAUUGG-------------------------------------------------- 21 1,-2 -----------CUGGCUAGGGAAAAUGAUUGGA------------------------------------------------- 139 1,-1 ------------UGGCUAGGGAAAAUGAUUGG-------------------------------------------------- 2 2,-2 ------------UGGCUAGGGAAAAUGAUUGGA------------------------------------------------- 17 2,-1 ------------------------------------------------UAUUCAUUUAUCCCCAGCC--------------- 2 0,-4 ------------------------------------------------UAUUCAUUUAUCCCCAGCCU-------------- 20 0,-3 ------------------------------------------------UAUUCAUUUAUCCCCAGCCUA------------- 23 0,-2 ------------------------------------------------UAUUCAUUUAUCCCCAGCCUAa------------ 2 0,-2 ------------------------------------------------UAUUCAUUUAUCCCCAGCCUAaa----------- 2 0,-2 ------------------------------------------------UAUUCAUUUAUCCCCAGCCUAu------------ 14 0,-2 ------------------------------------------------UAUUCAUUUAUCCCCAGCCUAC------------ 237 0,-1 ------------------------------------------------UAUUCAUUUAUCCCCAGCCUACc----------- 2 0,-1 ------------------------------------------------UAUUCAUUUAUCCCCAGCCUACu----------- 25 0,-1 ------------------------------------------------UAUUCAUUUAUCCCCAGCCUACA----------- 1091 0,0 ------------------------------------------------UAUUCAUUUAUCCCCAGCCUACAA---------- 24 0,1 -------------------------------------------------AUUCAUUUAUCCCCAGCCUAC------------ 4 1,-1 -------------------------------------------------AUUCAUUUAUCCCCAGCCUACA----------- 53 1,0 -------------------------------------------------AUUCAUUUAUCCCCAGCCUACAA---------- 2 1,1 >hsa-mir-665 3pM:43-62 Tumor ucuccucgaggggucucugccucuacccaggacucuuucaugACCAGGAGGCUGAGGCCCCUcacaggcggc ------------------------------------------ACCAGGAGGCUGAGGCCC------------ 10 0,-2 ------------------------------------------ACCAGGAGGCUGAGGCCCu----------- 2 0,-2 ------------------------------------------ACCAGGAGGCUGAGGCCCC----------- 13 0,-1 ------------------------------------------ACCAGGAGGCUGAGGCCCCU---------- 40 0,0 ------------------------------------------ACCAGGAGGCUGAGGCCCCUau-------- 2 0,0 ------------------------------------------ACCAGGAGGCUGAGGCCCCUu--------- 5 0,0 ------------------------------------------ACCAGGAGGCUGAGGCCCCUC--------- 28 0,1 ------------------------------------------ACCAGGAGGCUGAGGCCCCUCc-------- 5 0,1 ------------------------------------------ACCAGGAGGCUGAGGCCCCUCu-------- 17 0,1 ------------------------------------------ACCAGGAGGCUGAGGCCCCUCuu------- 2 0,1 ------------------------------------------ACCAGGAGGCUGAGGCCCCUCA-------- 69 0,2 ------------------------------------------ACCAGGAGGCUGAGGCCCCUCAa------- 6 0,2 ------------------------------------------ACCAGGAGGCUGAGGCCCCUCAaa------ 6 0,2 ------------------------------------------ACCAGGAGGCUGAGGCCCCUCAu------- 2 0,2 ------------------------------------------ACCAGGAGGCUGAGGCCCCUCAC------- 2 0,3 -------------------------------------------CCAGGAGGCUGAGGCCCCUCA-------- 4 1,2 >hsa-mir-671 5p:29-51;3p:68-88 Tumor gcaggugaacuggcaggccaggaagaggAGGAAGCCCUGGAGGGGCUGGAGgugauggauguuuuccUCCGGUUCUCAGGGCUCCACCucuuucgggccguagagccagggcuggugc ----------------------------AGGAAGCCCUGGAGGGGC------------------------------------------------------------------------ 4 0,-5 ----------------------------AGGAAGCCCUGGAGGGGCU----------------------------------------------------------------------- 14 0,-4 ----------------------------AGGAAGCCCUGGAGGGGCUG---------------------------------------------------------------------- 2 0,-3 ----------------------------AGGAAGCCCUGGAGGGGCUGa--------------------------------------------------------------------- 4 0,-3 ----------------------------AGGAAGCCCUGGAGGGGCUGG--------------------------------------------------------------------- 31 0,-2 ----------------------------AGGAAGCCCUGGAGGGGCUGGA-------------------------------------------------------------------- 185 0,-1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAa------------------------------------------------------------------- 86 0,-1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAaa------------------------------------------------------------------ 23 0,-1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAau------------------------------------------------------------------ 103 0,-1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAc------------------------------------------------------------------- 2 0,-1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAu------------------------------------------------------------------- 42 0,-1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAuu------------------------------------------------------------------ 5 0,-1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAG------------------------------------------------------------------- 730 0,0 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGa------------------------------------------------------------------ 380 0,0 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGaa----------------------------------------------------------------- 19 0,0 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGau----------------------------------------------------------------- 14 0,0 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGc------------------------------------------------------------------ 3 0,0 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGu------------------------------------------------------------------ 427 0,0 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGuu----------------------------------------------------------------- 7 0,0 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGG------------------------------------------------------------------ 786 0,1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGGa----------------------------------------------------------------- 17 0,1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGGg----------------------------------------------------------------- 6 0,1 ----------------------------AGGAAGCCCUGGAGGGGCUGGAGGU----------------------------------------------------------------- 115 0,2 -----------------------------GGAAGCCCUGGAGGGGCUGGAa------------------------------------------------------------------- 2 1,-1 -----------------------------GGAAGCCCUGGAGGGGCUGGAG------------------------------------------------------------------- 2 1,0 -----------------------------GGAAGCCCUGGAGGGGCUGGAGa------------------------------------------------------------------ 2 1,0 -----------------------------GGAAGCCCUGGAGGGGCUGGAGG------------------------------------------------------------------ 7 1,1 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCA-------------------------------- 20 0,-2 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCAa------------------------------- 6 0,-2 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCAu------------------------------- 3 0,-2 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCAuu------------------------------ 14 0,-2 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCAC------------------------------- 10 0,-1 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCACa------------------------------ 2 0,-1 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCACu------------------------------ 21 0,-1 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCACC------------------------------ 86 0,0 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCACCa----------------------------- 2 0,0 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCACCU----------------------------- 18 0,1 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCACCUu---------------------------- 2 0,1 -------------------------------------------------------------------UCCGGUUCUCAGGGCUCCACCUuu--------------------------- 2 0,1 >hsa-mir-675 MA:10-32;mi:45-64 Tumor cccagggucUGGUGCGGAGAGGGCCCACAGUGgacuuggugacgCUGUAUGCCCUCACCGCUCAgccccuggg ---------UGGUGCGGAGAGGGCCCAu--------------------------------------------- 2 0,-5 ---------UGGUGCGGAGAGGGCCCACA-------------------------------------------- 2 0,-3 ---------UGGUGCGGAGAGGGCCCACAG------------------------------------------- 2 0,-2 ---------UGGUGCGGAGAGGGCCCACAGU------------------------------------------ 11 0,-1 ---------UGGUGCGGAGAGGGCCCACAGUG----------------------------------------- 18 0,0 ---------UGGUGCGGAGAGGGCCCACAGUGa---------------------------------------- 7 0,0 ---------UGGUGCGGAGAGGGCCCACAGUGu---------------------------------------- 11 0,0 --------------------------------------------CUGUAUGCCCUCACCGCUC---------- 3 0,-1 --------------------------------------------CUGUAUGCCCUCACCGCUCAG-------- 4 0,1 --------------------------------------------CUGUAUGCCCUCACCGCUCAGa------- 8 0,1 --------------------------------------------CUGUAUGCCCUCACCGCUCAGu------- 2 0,1 --------------------------------------------CUGUAUGCCCUCACCGCUCAGC------- 80 0,2 ---------------------------------------------UGUAUGCCCUCACCGCUCAGC------- 4 1,2 >hsa-mir-7-1 MA:24-46;mi:66-87 Tumor uuggauguuggccuaguucugugUGGAAGACUAGUGAUUUUGUUGUuuuuagauaacuaaaucgaCAACAAAUCACAGUCUGCCAUAuggcacaggccaugccucuacag -----------------------UGGAAGACUAGUGAUUUU--------------------------------------------------------------------- 68 0,-5 -----------------------UGGAAGACUAGUGAUUUUG-------------------------------------------------------------------- 67 0,-4 -----------------------UGGAAGACUAGUGAUUUUGa------------------------------------------------------------------- 11 0,-4 -----------------------UGGAAGACUAGUGAUUUUGU------------------------------------------------------------------- 250 0,-3 -----------------------UGGAAGACUAGUGAUUUUGUU------------------------------------------------------------------ 832 0,-2 -----------------------UGGAAGACUAGUGAUUUUGUUa----------------------------------------------------------------- 33 0,-2 -----------------------UGGAAGACUAGUGAUUUUGUUaa---------------------------------------------------------------- 3 0,-2 -----------------------UGGAAGACUAGUGAUUUUGUUau---------------------------------------------------------------- 9 0,-2 -----------------------UGGAAGACUAGUGAUUUUGUUu----------------------------------------------------------------- 15 0,-2 -----------------------UGGAAGACUAGUGAUUUUGUUuu---------------------------------------------------------------- 9 0,-2 -----------------------UGGAAGACUAGUGAUUUUGUUG----------------------------------------------------------------- 1487 0,-1 -----------------------UGGAAGACUAGUGAUUUUGUUGa---------------------------------------------------------------- 48 0,-1 -----------------------UGGAAGACUAGUGAUUUUGUUGc---------------------------------------------------------------- 2 0,-1 -----------------------UGGAAGACUAGUGAUUUUGUUGU---------------------------------------------------------------- 5990 0,0 -----------------------UGGAAGACUAGUGAUUUUGUUGUa--------------------------------------------------------------- 20 0,0 -----------------------UGGAAGACUAGUGAUUUUGUUGUaa-------------------------------------------------------------- 10 0,0 -----------------------UGGAAGACUAGUGAUUUUGUUGUau-------------------------------------------------------------- 11 0,0 -----------------------UGGAAGACUAGUGAUUUUGUUGUc--------------------------------------------------------------- 8 0,0 -----------------------UGGAAGACUAGUGAUUUUGUUGUg--------------------------------------------------------------- 2 0,0 -----------------------UGGAAGACUAGUGAUUUUGUUGUU--------------------------------------------------------------- 15353 0,1 -----------------------UGGAAGACUAGUGAUUUUGUUGUUa-------------------------------------------------------------- 236 0,1 -----------------------UGGAAGACUAGUGAUUUUGUUGUUU-------------------------------------------------------------- 403 0,2 ------------------------GGAAGACUAGUGAUUUUGUU------------------------------------------------------------------ 16 1,-2 ------------------------GGAAGACUAGUGAUUUUGUUu----------------------------------------------------------------- 2 1,-2 ------------------------GGAAGACUAGUGAUUUUGUUG----------------------------------------------------------------- 29 1,-1 ------------------------GGAAGACUAGUGAUUUUGUUGa---------------------------------------------------------------- 3 1,-1 ------------------------GGAAGACUAGUGAUUUUGUUGU---------------------------------------------------------------- 140 1,0 ------------------------GGAAGACUAGUGAUUUUGUUGUU--------------------------------------------------------------- 351 1,1 ------------------------GGAAGACUAGUGAUUUUGUUGUUU-------------------------------------------------------------- 6 1,2 -----------------------------------------------------------------CAACAAAUCACAGUCUGCC-------------------------- 6 0,-3 -----------------------------------------------------------------CAACAAAUCACAGUCUGCCA------------------------- 56 0,-2 -----------------------------------------------------------------CAACAAAUCACAGUCUGCCAa------------------------ 2 0,-2 -----------------------------------------------------------------CAACAAAUCACAGUCUGCCAU------------------------ 197 0,-1 -----------------------------------------------------------------CAACAAAUCACAGUCUGCCAUu----------------------- 229 0,-1 -----------------------------------------------------------------CAACAAAUCACAGUCUGCCAUA----------------------- 754 0,0 -----------------------------------------------------------------CAACAAAUCACAGUCUGCCAUAa---------------------- 24 0,0 -----------------------------------------------------------------CAACAAAUCACAGUCUGCCAUAU---------------------- 22 0,1 ------------------------------------------------------------------AACAAAUCACAGUCUGCCAU------------------------ 4 1,-1 ------------------------------------------------------------------AACAAAUCACAGUCUGCCAUc----------------------- 2 1,-1 ------------------------------------------------------------------AACAAAUCACAGUCUGCCAUu----------------------- 35 1,-1 ------------------------------------------------------------------AACAAAUCACAGUCUGCCAUuu---------------------- 2 1,-1 ------------------------------------------------------------------AACAAAUCACAGUCUGCCAUA----------------------- 194 1,0 ------------------------------------------------------------------AACAAAUCACAGUCUGCCAUAa---------------------- 6 1,0 ------------------------------------------------------------------AACAAAUCACAGUCUGCCAUAg---------------------- 2 1,0 ------------------------------------------------------------------AACAAAUCACAGUCUGCCAUAU---------------------- 8 1,1 -------------------------------------------------------------------ACAAAUCACAGUCUGCCAUuu---------------------- 2 2,-1 -------------------------------------------------------------------ACAAAUCACAGUCUGCCAUA----------------------- 3 2,0 >hsa-mir-7-2 MA:32-54;mi:72-93 Tumor cuggauacagaguggaccggcuggccccaucUGGAAGACUAGUGAUUUUGUUGUugucuuacugcgcucaaCAACAAAUCCCAGUCUACCUAAuggugccagccaucgca ------------------------------CUGGAAGACUAGUGAUUUUGUUG--------------------------------------------------------- 4 -1,-1 ------------------------------CUGGAAGACUAGUGAUUUUGUUGU-------------------------------------------------------- 7 -1,0 ------------------------------CUGGAAGACUAGUGAUUUUGUUGUU------------------------------------------------------- 16 -1,1 -------------------------------UGGAAGACUAGUGAUUUU------------------------------------------------------------- 68 0,-5 -------------------------------UGGAAGACUAGUGAUUUUG------------------------------------------------------------ 67 0,-4 -------------------------------UGGAAGACUAGUGAUUUUGa----------------------------------------------------------- 11 0,-4 -------------------------------UGGAAGACUAGUGAUUUUGU----------------------------------------------------------- 250 0,-3 -------------------------------UGGAAGACUAGUGAUUUUGUU---------------------------------------------------------- 832 0,-2 -------------------------------UGGAAGACUAGUGAUUUUGUUa--------------------------------------------------------- 33 0,-2 -------------------------------UGGAAGACUAGUGAUUUUGUUaa-------------------------------------------------------- 3 0,-2 -------------------------------UGGAAGACUAGUGAUUUUGUUau-------------------------------------------------------- 9 0,-2 -------------------------------UGGAAGACUAGUGAUUUUGUUu--------------------------------------------------------- 15 0,-2 -------------------------------UGGAAGACUAGUGAUUUUGUUuu-------------------------------------------------------- 9 0,-2 -------------------------------UGGAAGACUAGUGAUUUUGUUG--------------------------------------------------------- 1487 0,-1 -------------------------------UGGAAGACUAGUGAUUUUGUUGa-------------------------------------------------------- 48 0,-1 -------------------------------UGGAAGACUAGUGAUUUUGUUGc-------------------------------------------------------- 2 0,-1 -------------------------------UGGAAGACUAGUGAUUUUGUUGU-------------------------------------------------------- 5990 0,0 -------------------------------UGGAAGACUAGUGAUUUUGUUGUa------------------------------------------------------- 20 0,0 -------------------------------UGGAAGACUAGUGAUUUUGUUGUaa------------------------------------------------------ 10 0,0 -------------------------------UGGAAGACUAGUGAUUUUGUUGUau------------------------------------------------------ 11 0,0 -------------------------------UGGAAGACUAGUGAUUUUGUUGUc------------------------------------------------------- 8 0,0 -------------------------------UGGAAGACUAGUGAUUUUGUUGUg------------------------------------------------------- 2 0,0 -------------------------------UGGAAGACUAGUGAUUUUGUUGUU------------------------------------------------------- 15353 0,1 -------------------------------UGGAAGACUAGUGAUUUUGUUGUUa------------------------------------------------------ 236 0,1 -------------------------------UGGAAGACUAGUGAUUUUGUUGUUG------------------------------------------------------ 11 0,2 --------------------------------GGAAGACUAGUGAUUUUGUU---------------------------------------------------------- 16 1,-2 --------------------------------GGAAGACUAGUGAUUUUGUUu--------------------------------------------------------- 2 1,-2 --------------------------------GGAAGACUAGUGAUUUUGUUG--------------------------------------------------------- 29 1,-1 --------------------------------GGAAGACUAGUGAUUUUGUUGa-------------------------------------------------------- 3 1,-1 --------------------------------GGAAGACUAGUGAUUUUGUUGU-------------------------------------------------------- 140 1,0 --------------------------------GGAAGACUAGUGAUUUUGUUGUU------------------------------------------------------- 351 1,1 >hsa-mir-7-3 5pM:31-53 Tumor agauuagaguggcuguggucuagugcugugUGGAAGACUAGUGAUUUUGUUGUucugauguacuacgacaacaagucacagccggccucauagcgcagacucccuucgac ------------------------------UGGAAGACUAGUGAUUUU-------------------------------------------------------------- 68 0,-5 ------------------------------UGGAAGACUAGUGAUUUUG------------------------------------------------------------- 67 0,-4 ------------------------------UGGAAGACUAGUGAUUUUGa------------------------------------------------------------ 11 0,-4 ------------------------------UGGAAGACUAGUGAUUUUGU------------------------------------------------------------ 250 0,-3 ------------------------------UGGAAGACUAGUGAUUUUGUU----------------------------------------------------------- 832 0,-2 ------------------------------UGGAAGACUAGUGAUUUUGUUa---------------------------------------------------------- 33 0,-2 ------------------------------UGGAAGACUAGUGAUUUUGUUaa--------------------------------------------------------- 3 0,-2 ------------------------------UGGAAGACUAGUGAUUUUGUUau--------------------------------------------------------- 9 0,-2 ------------------------------UGGAAGACUAGUGAUUUUGUUu---------------------------------------------------------- 15 0,-2 ------------------------------UGGAAGACUAGUGAUUUUGUUuu--------------------------------------------------------- 9 0,-2 ------------------------------UGGAAGACUAGUGAUUUUGUUG---------------------------------------------------------- 1487 0,-1 ------------------------------UGGAAGACUAGUGAUUUUGUUGa--------------------------------------------------------- 48 0,-1 ------------------------------UGGAAGACUAGUGAUUUUGUUGc--------------------------------------------------------- 2 0,-1 ------------------------------UGGAAGACUAGUGAUUUUGUUGU--------------------------------------------------------- 5990 0,0 ------------------------------UGGAAGACUAGUGAUUUUGUUGUa-------------------------------------------------------- 20 0,0 ------------------------------UGGAAGACUAGUGAUUUUGUUGUaa------------------------------------------------------- 10 0,0 ------------------------------UGGAAGACUAGUGAUUUUGUUGUau------------------------------------------------------- 11 0,0 ------------------------------UGGAAGACUAGUGAUUUUGUUGUc-------------------------------------------------------- 8 0,0 ------------------------------UGGAAGACUAGUGAUUUUGUUGUg-------------------------------------------------------- 2 0,0 ------------------------------UGGAAGACUAGUGAUUUUGUUGUU-------------------------------------------------------- 15353 0,1 ------------------------------UGGAAGACUAGUGAUUUUGUUGUUa------------------------------------------------------- 236 0,1 ------------------------------UGGAAGACUAGUGAUUUUGUUGUUC------------------------------------------------------- 2 0,2 -------------------------------GGAAGACUAGUGAUUUUGUU----------------------------------------------------------- 16 1,-2 -------------------------------GGAAGACUAGUGAUUUUGUUu---------------------------------------------------------- 2 1,-2 -------------------------------GGAAGACUAGUGAUUUUGUUG---------------------------------------------------------- 29 1,-1 -------------------------------GGAAGACUAGUGAUUUUGUUGa--------------------------------------------------------- 3 1,-1 -------------------------------GGAAGACUAGUGAUUUUGUUGU--------------------------------------------------------- 140 1,0 -------------------------------GGAAGACUAGUGAUUUUGUUGUU-------------------------------------------------------- 351 1,1 >hsa-mir-708 MA:11-33;mi:57-78 Tumor aacugcccucAAGGAGCUUACAAUCUAGCUGGGgguaaaugacuugcacaugaacaCAACUAGACUGUGAGCUUCUAGagggcaggga ---------CAAGGAGCUUACAAUCUAGCUGG-------------------------------------------------------- 2 -1,-1 ---------CAAGGAGCUUACAAUCUAGCUGGG------------------------------------------------------- 2 -1,0 ----------AAGGAGCUUACAAUCUAG------------------------------------------------------------ 45 0,-5 ----------AAGGAGCUUACAAUCUAGa----------------------------------------------------------- 4 0,-5 ----------AAGGAGCUUACAAUCUAGC----------------------------------------------------------- 23 0,-4 ----------AAGGAGCUUACAAUCUAGCa---------------------------------------------------------- 6 0,-4 ----------AAGGAGCUUACAAUCUAGCU---------------------------------------------------------- 398 0,-3 ----------AAGGAGCUUACAAUCUAGCUa--------------------------------------------------------- 6 0,-3 ----------AAGGAGCUUACAAUCUAGCUaa-------------------------------------------------------- 3 0,-3 ----------AAGGAGCUUACAAUCUAGCUG--------------------------------------------------------- 1112 0,-2 ----------AAGGAGCUUACAAUCUAGCUGa-------------------------------------------------------- 544 0,-2 ----------AAGGAGCUUACAAUCUAGCUGaa------------------------------------------------------- 17 0,-2 ----------AAGGAGCUUACAAUCUAGCUGc-------------------------------------------------------- 7 0,-2 ----------AAGGAGCUUACAAUCUAGCUGu-------------------------------------------------------- 249 0,-2 ----------AAGGAGCUUACAAUCUAGCUGuu------------------------------------------------------- 2 0,-2 ----------AAGGAGCUUACAAUCUAGCUGG-------------------------------------------------------- 9874 0,-1 ----------AAGGAGCUUACAAUCUAGCUGGa------------------------------------------------------- 2170 0,-1 ----------AAGGAGCUUACAAUCUAGCUGGaa------------------------------------------------------ 57 0,-1 ----------AAGGAGCUUACAAUCUAGCUGGau------------------------------------------------------ 8 0,-1 ----------AAGGAGCUUACAAUCUAGCUGGc------------------------------------------------------- 4 0,-1 ----------AAGGAGCUUACAAUCUAGCUGGu------------------------------------------------------- 417 0,-1 ----------AAGGAGCUUACAAUCUAGCUGGuu------------------------------------------------------ 4 0,-1 ----------AAGGAGCUUACAAUCUAGCUGGG------------------------------------------------------- 4151 0,0 ----------AAGGAGCUUACAAUCUAGCUGGGa------------------------------------------------------ 890 0,0 ----------AAGGAGCUUACAAUCUAGCUGGGaa----------------------------------------------------- 32 0,0 ----------AAGGAGCUUACAAUCUAGCUGGGau----------------------------------------------------- 62 0,0 ----------AAGGAGCUUACAAUCUAGCUGGGc------------------------------------------------------ 5 0,0 ----------AAGGAGCUUACAAUCUAGCUGGGu------------------------------------------------------ 542 0,0 ----------AAGGAGCUUACAAUCUAGCUGGGuu----------------------------------------------------- 10 0,0 ----------AAGGAGCUUACAAUCUAGCUGGGG------------------------------------------------------ 2 0,1 -----------AGGAGCUUACAAUCUAGCUG--------------------------------------------------------- 4 1,-2 -----------AGGAGCUUACAAUCUAGCUGa-------------------------------------------------------- 2 1,-2 -----------AGGAGCUUACAAUCUAGCUGG-------------------------------------------------------- 180 1,-1 -----------AGGAGCUUACAAUCUAGCUGGa------------------------------------------------------- 14 1,-1 -----------AGGAGCUUACAAUCUAGCUGGu------------------------------------------------------- 4 1,-1 -----------AGGAGCUUACAAUCUAGCUGGG------------------------------------------------------- 78 1,0 -----------AGGAGCUUACAAUCUAGCUGGGa------------------------------------------------------ 6 1,0 -----------AGGAGCUUACAAUCUAGCUGGGu------------------------------------------------------ 2 1,0 --------------------------------------------------------CAACUAGACUGUGAGCUUCU------------ 104 0,-2 --------------------------------------------------------CAACUAGACUGUGAGCUUCUA----------- 34 0,-1 --------------------------------------------------------CAACUAGACUGUGAGCUUCUAG---------- 296 0,0 --------------------------------------------------------CAACUAGACUGUGAGCUUCUAGu--------- 26 0,0 --------------------------------------------------------CAACUAGACUGUGAGCUUCUAGA--------- 228 0,1 ---------------------------------------------------------AACUAGACUGUGAGCUUCU------------ 11 1,-2 ---------------------------------------------------------AACUAGACUGUGAGCUUCUA----------- 8 1,-1 ---------------------------------------------------------AACUAGACUGUGAGCUUCUAG---------- 252 1,0 ---------------------------------------------------------AACUAGACUGUGAGCUUCUAGu--------- 2 1,0 ---------------------------------------------------------AACUAGACUGUGAGCUUCUAGA--------- 517 1,1 ---------------------------------------------------------AACUAGACUGUGAGCUUCUAGAa-------- 2 1,1 ----------------------------------------------------------ACUAGACUGUGAGCUUCUAa---------- 2 2,-1 ----------------------------------------------------------ACUAGACUGUGAGCUUCUAG---------- 12 2,0 ----------------------------------------------------------ACUAGACUGUGAGCUUCUAGu--------- 2 2,0 ----------------------------------------------------------ACUAGACUGUGAGCUUCUAGA--------- 45 2,1 ----------------------------------------------------------ACUAGACUGUGAGCUUCUAGAG-------- 2 2,2 >hsa-mir-720 5pM:27-43 Tumor ccggaucucacacggugguguuaauaUCUCGCUGGGGCCUCCAaaauguugugcccagggguguuagagaaaacaccacacuuugagaugaauuaagaguccuuuauuag -------------------------AUCUCGCUGGGGCCUCCA------------------------------------------------------------------- 557 -1,0 >hsa-mir-744 MA:11-32;mi:68-89 Tumor uugggcaaggUGCGGGGCUAGGGCUAACAGCAgucuuacugaagguuuccuggaaaccacgcacaugCUGUUGCCACUAACCUCAACCUuacucgguc ----------UGCGGGGCUAGGGCUAAC---------------------------------------------------------------------- 28 0,-4 ----------UGCGGGGCUAGGGCUAACA--------------------------------------------------------------------- 42 0,-3 ----------UGCGGGGCUAGGGCUAACAa-------------------------------------------------------------------- 2 0,-3 ----------UGCGGGGCUAGGGCUAACAG-------------------------------------------------------------------- 387 0,-2 ----------UGCGGGGCUAGGGCUAACAGa------------------------------------------------------------------- 144 0,-2 ----------UGCGGGGCUAGGGCUAACAGaa------------------------------------------------------------------ 12 0,-2 ----------UGCGGGGCUAGGGCUAACAGau------------------------------------------------------------------ 5 0,-2 ----------UGCGGGGCUAGGGCUAACAGu------------------------------------------------------------------- 103 0,-2 ----------UGCGGGGCUAGGGCUAACAGuu------------------------------------------------------------------ 5 0,-2 ----------UGCGGGGCUAGGGCUAACAGC------------------------------------------------------------------- 1056 0,-1 ----------UGCGGGGCUAGGGCUAACAGCc------------------------------------------------------------------ 35 0,-1 ----------UGCGGGGCUAGGGCUAACAGCg------------------------------------------------------------------ 2 0,-1 ----------UGCGGGGCUAGGGCUAACAGCu------------------------------------------------------------------ 60 0,-1 ----------UGCGGGGCUAGGGCUAACAGCuu----------------------------------------------------------------- 2 0,-1 ----------UGCGGGGCUAGGGCUAACAGCA------------------------------------------------------------------ 2440 0,0 ----------UGCGGGGCUAGGGCUAACAGCAa----------------------------------------------------------------- 239 0,0 ----------UGCGGGGCUAGGGCUAACAGCAaa---------------------------------------------------------------- 2 0,0 ----------UGCGGGGCUAGGGCUAACAGCAau---------------------------------------------------------------- 6 0,0 ----------UGCGGGGCUAGGGCUAACAGCAu----------------------------------------------------------------- 208 0,0 ----------UGCGGGGCUAGGGCUAACAGCAuu---------------------------------------------------------------- 5 0,0 ----------UGCGGGGCUAGGGCUAACAGCAG----------------------------------------------------------------- 14 0,1 ----------UGCGGGGCUAGGGCUAACAGCAGU---------------------------------------------------------------- 2 0,2 -----------GCGGGGCUAGGGCUAACA--------------------------------------------------------------------- 2 1,-3 -----------GCGGGGCUAGGGCUAACAG-------------------------------------------------------------------- 6 1,-2 -----------GCGGGGCUAGGGCUAACAGu------------------------------------------------------------------- 2 1,-2 -----------GCGGGGCUAGGGCUAACAGC------------------------------------------------------------------- 32 1,-1 -----------GCGGGGCUAGGGCUAACAGCA------------------------------------------------------------------ 132 1,0 -----------GCGGGGCUAGGGCUAACAGCAa----------------------------------------------------------------- 2 1,0 -----------GCGGGGCUAGGGCUAACAGCAu----------------------------------------------------------------- 2 1,0 -------------------------------------------------------------------CUGUUGCCACUAACCUCAAuu---------- 2 0,-3 -------------------------------------------------------------------CUGUUGCCACUAACCUCAACu---------- 59 0,-2 -------------------------------------------------------------------CUGUUGCCACUAACCUCAACC---------- 35 0,-1 >hsa-mir-758 3pM:52-73 Tumor gccuggauacaugagaugguugaccagagagcacacgcuuuauuugugccgUUUGUGACCUGGUCCACUAACCcucaguaucuaaugc ---------------------------------------------------UUUGUGACCUGGUCCACUAA----------------- 6 0,-2 ---------------------------------------------------UUUGUGACCUGGUCCACUAAu---------------- 2 0,-2 ---------------------------------------------------UUUGUGACCUGGUCCACUAAC---------------- 47 0,-1 ---------------------------------------------------UUUGUGACCUGGUCCACUAACa--------------- 2 0,-1 ---------------------------------------------------UUUGUGACCUGGUCCACUAACu--------------- 17 0,-1 ---------------------------------------------------UUUGUGACCUGGUCCACUAACC--------------- 23 0,0 ---------------------------------------------------UUUGUGACCUGGUCCACUAACCa-------------- 2 0,0 >hsa-mir-760 3pM:49-68 Tumor ggcgcgucgccccccucaguccaccagagcccggauaccucagaaauuCGGCUCUGGGUCUGUGGGGAgcgaaaugcaac -----------------------------------------------UCGGCUCUGGGUCUGUGGGGA------------ 2 -1,0 -----------------------------------------------UCGGCUCUGGGUCUGUGGGGAGu---------- 4 -1,1 ------------------------------------------------CGGCUCUGGGUCUGUGGGaa------------ 2 0,-2 ------------------------------------------------CGGCUCUGGGUCUGUGGGGA------------ 279 0,0 ------------------------------------------------CGGCUCUGGGUCUGUGGGGAGu---------- 20 0,1 -------------------------------------------------GGCUCUGGGUCUGUGGGGA------------ 2 1,0 >hsa-mir-765 3pM:69-89 Tumor uuuaggcgcugaugaaaguggaguucaguagacagcccuuuucaagcccuacgagaaacugggguuucUGGAGGAGAAGGAAGGUGAUGaaggaucuguucucgugagccugaa --------------------------------------------------------------------UGGAGGAGAAGGAAGGUGA--------------------------- 2 0,-2 >hsa-mir-766 3pM:65-86 Tumor gcauccucaggaccugggcuugggugguaggaggaauuggugcuggucuuucauuuuggauuugACUCCAGCCCCACAGCCUCAGCcaccccagccaauugucauaggagc ----------------------------AGGAGGAAUUGGUGCUGGU---------------------------------------------------------------- 2 ----------------------------------------------------------------ACUCCAGCCCCACAGCCUCA--------------------------- 87 0,-2 ----------------------------------------------------------------ACUCCAGCCCCACAGCCUCAa-------------------------- 2 0,-2 ----------------------------------------------------------------ACUCCAGCCCCACAGCCUCAG-------------------------- 155 0,-1 ----------------------------------------------------------------ACUCCAGCCCCACAGCCUCAGa------------------------- 75 0,-1 ----------------------------------------------------------------ACUCCAGCCCCACAGCCUCAGaa------------------------ 7 0,-1 ----------------------------------------------------------------ACUCCAGCCCCACAGCCUCAGau------------------------ 2 0,-1 ----------------------------------------------------------------ACUCCAGCCCCACAGCCUCAGu------------------------- 57 0,-1 ----------------------------------------------------------------ACUCCAGCCCCACAGCCUCAGC------------------------- 160 0,0 ----------------------------------------------------------------ACUCCAGCCCCACAGCCUCAGCa------------------------ 3 0,0 ----------------------------------------------------------------ACUCCAGCCCCACAGCCUCAGCu------------------------ 6 0,0 -----------------------------------------------------------------CUCCAGCCCCACAGCCUCAGC------------------------- 4 1,0 >hsa-mir-767 5p:27-49;3p:61-83 Tumor gcuuuuauauuguagguuuuugcucaUGCACCAUGGUUGUCUGAGCAUGcagcaugcuugUCUGCUCAUACCCCAUGGUUUCUgagcaggaaccuucauugucuacugc --------------------------UGCACCAUGGUUGUCUGAGC--------------------------------------------------------------- 11 0,-3 --------------------------UGCACCAUGGUUGUCUGAGCA-------------------------------------------------------------- 14 0,-2 --------------------------UGCACCAUGGUUGUCUGAGCAa------------------------------------------------------------- 2 0,-2 --------------------------UGCACCAUGGUUGUCUGAGCAU------------------------------------------------------------- 32 0,-1 --------------------------UGCACCAUGGUUGUCUGAGCAUG------------------------------------------------------------ 37 0,0 --------------------------UGCACCAUGGUUGUCUGAGCAUGa----------------------------------------------------------- 2 0,0 --------------------------UGCACCAUGGUUGUCUGAGCAUGu----------------------------------------------------------- 10 0,0 --------------------------UGCACCAUGGUUGUCUGAGCAUGC----------------------------------------------------------- 13 0,1 ------------------------------------------------------------UCUGCUCAUACCCCAUGGUU----------------------------- 5 0,-3 ------------------------------------------------------------UCUGCUCAUACCCCAUGGUUU---------------------------- 5 0,-2 ------------------------------------------------------------UCUGCUCAUACCCCAUGGUUUC--------------------------- 2 0,-1 -------------------------------------------------------------CUGCUCAUACCCCAUGGUUUC--------------------------- 2 1,-1 -------------------------------------------------------------CUGCUCAUACCCCAUGGUUUCU-------------------------- 2 1,0 >hsa-mir-769 5p:30-51;3p:69-91 Tumor gccuuggugcugauuccugggcucugaccUGAGACCUCUGGGUUCUGAGCUgugauguugcucucgagCUGGGAUCUCCGGGGUCUUGGUUcagggccggggccucuggguuccaagc ----------------------------CUGAGACCUCUGGGUUCUGA---------------------------------------------------------------------- 2 -1,-3 ----------------------------CUGAGACCUCUGGGUUCUGAG--------------------------------------------------------------------- 10 -1,-2 ----------------------------CUGAGACCUCUGGGUUCUGAGC-------------------------------------------------------------------- 6 -1,-1 ----------------------------CUGAGACCUCUGGGUUCUGAGCU------------------------------------------------------------------- 26 -1,0 -----------------------------UGAGACCUCUGGGUUCUG----------------------------------------------------------------------- 22 0,-4 -----------------------------UGAGACCUCUGGGUUCUGA---------------------------------------------------------------------- 91 0,-3 -----------------------------UGAGACCUCUGGGUUCUGAa--------------------------------------------------------------------- 2 0,-3 -----------------------------UGAGACCUCUGGGUUCUGAaa-------------------------------------------------------------------- 13 0,-3 -----------------------------UGAGACCUCUGGGUUCUGAG--------------------------------------------------------------------- 779 0,-2 -----------------------------UGAGACCUCUGGGUUCUGAGa-------------------------------------------------------------------- 526 0,-2 -----------------------------UGAGACCUCUGGGUUCUGAGaa------------------------------------------------------------------- 26 0,-2 -----------------------------UGAGACCUCUGGGUUCUGAGau------------------------------------------------------------------- 7 0,-2 -----------------------------UGAGACCUCUGGGUUCUGAGu-------------------------------------------------------------------- 141 0,-2 -----------------------------UGAGACCUCUGGGUUCUGAGuu------------------------------------------------------------------- 4 0,-2 -----------------------------UGAGACCUCUGGGUUCUGAGC-------------------------------------------------------------------- 1267 0,-1 -----------------------------UGAGACCUCUGGGUUCUGAGCa------------------------------------------------------------------- 65 0,-1 -----------------------------UGAGACCUCUGGGUUCUGAGCaa------------------------------------------------------------------ 5 0,-1 -----------------------------UGAGACCUCUGGGUUCUGAGCau------------------------------------------------------------------ 2 0,-1 -----------------------------UGAGACCUCUGGGUUCUGAGCU------------------------------------------------------------------- 3664 0,0 -----------------------------UGAGACCUCUGGGUUCUGAGCUa------------------------------------------------------------------ 100 0,0 -----------------------------UGAGACCUCUGGGUUCUGAGCUaa----------------------------------------------------------------- 18 0,0 -----------------------------UGAGACCUCUGGGUUCUGAGCUau----------------------------------------------------------------- 35 0,0 -----------------------------UGAGACCUCUGGGUUCUGAGCUu------------------------------------------------------------------ 294 0,0 -----------------------------UGAGACCUCUGGGUUCUGAGCUuu----------------------------------------------------------------- 98 0,0 -----------------------------UGAGACCUCUGGGUUCUGAGCUG------------------------------------------------------------------ 2 0,1 -----------------------------UGAGACCUCUGGGUUCUGAGCUGa----------------------------------------------------------------- 2 0,1 -----------------------------UGAGACCUCUGGGUUCUGAGCUGU----------------------------------------------------------------- 2 0,2 ------------------------------GAGACCUCUGGGUUCUGA---------------------------------------------------------------------- 4 1,-3 ------------------------------GAGACCUCUGGGUUCUGAG--------------------------------------------------------------------- 10 1,-2 ------------------------------GAGACCUCUGGGUUCUGAGa-------------------------------------------------------------------- 5 1,-2 ------------------------------GAGACCUCUGGGUUCUGAGu-------------------------------------------------------------------- 3 1,-2 ------------------------------GAGACCUCUGGGUUCUGAGC-------------------------------------------------------------------- 32 1,-1 ------------------------------GAGACCUCUGGGUUCUGAGCa------------------------------------------------------------------- 2 1,-1 ------------------------------GAGACCUCUGGGUUCUGAGCU------------------------------------------------------------------- 149 1,0 ------------------------------GAGACCUCUGGGUUCUGAGCUa------------------------------------------------------------------ 2 1,0 ------------------------------GAGACCUCUGGGUUCUGAGCUuu----------------------------------------------------------------- 2 1,0 --------------------------------------------------------------------CUGGGAUCUCCGGGGUCUU------------------------------- 2 0,-4 --------------------------------------------------------------------CUGGGAUCUCCGGGGUCUUGu----------------------------- 2 0,-3 --------------------------------------------------------------------CUGGGAUCUCCGGGGUCUUGG----------------------------- 4 0,-2 --------------------------------------------------------------------CUGGGAUCUCCGGGGUCUUGGa---------------------------- 4 0,-2 --------------------------------------------------------------------CUGGGAUCUCCGGGGUCUUGGU---------------------------- 14 0,-1 --------------------------------------------------------------------CUGGGAUCUCCGGGGUCUUGGUa--------------------------- 2 0,-1 --------------------------------------------------------------------CUGGGAUCUCCGGGGUCUUGGUU--------------------------- 41 0,0 --------------------------------------------------------------------CUGGGAUCUCCGGGGUCUUGGUUu-------------------------- 2 0,0 ---------------------------------------------------------------------UGGGAUCUCCGGGGUCUUG------------------------------ 2 1,-3 ---------------------------------------------------------------------UGGGAUCUCCGGGGUCUUGGau--------------------------- 2 1,-2 ---------------------------------------------------------------------UGGGAUCUCCGGGGUCUUGGU---------------------------- 14 1,-1 ---------------------------------------------------------------------UGGGAUCUCCGGGGUCUUGGUU--------------------------- 77 1,0 ---------------------------------------------------------------------UGGGAUCUCCGGGGUCUUGGUUu-------------------------- 10 1,0 ---------------------------------------------------------------------UGGGAUCUCCGGGGUCUUGGUUuu------------------------- 2 1,0 >hsa-mir-873 5pM:11-31 Tumor gugugcauuuGCAGGAACUUGUGAGUCUCCUauugaaaaugaacaggagacugaugaguucccgggaacacccacaa ---------UGCAGGAACUUGUGAGUCU------------------------------------------------- 7 -1,-3 ---------UGCAGGAACUUGUGAGUCUCC----------------------------------------------- 2 -1,-1 ---------UGCAGGAACUUGUGAGUCUCCU---------------------------------------------- 2 -1,0 ----------GCAGGAACUUGUGAGUCU------------------------------------------------- 3 0,-3 ----------GCAGGAACUUGUGAGUCUCCU---------------------------------------------- 29 0,0 ----------GCAGGAACUUGUGAGUCUCCUu--------------------------------------------- 2 0,0 ----------GCAGGAACUUGUGAGUCUCCUA--------------------------------------------- 12 0,1 ---------------------------------------------GGAGACUGAUGAGUUCCCGGGA---------- 2 >hsa-mir-874 3pM:47-68 Tumor uuagcccugcggccccacgcaccaggguaagagagacucucgcuucCUGCCCUGGCCCGAGGGACCGAcuggcugggc ---------CGGCCCCACGCACCAGGGUAA------------------------------------------------ 2 ---------CGGCCCCACGCACCAGGGUAAG----------------------------------------------- 21 ---------CGGCCCCACGCACCAGGGUAAGu---------------------------------------------- 2 ---------CGGCCCCACGCACCAGGGUAAGA---------------------------------------------- 54 ----------GGCCCCACGCACCAGGGUAAG----------------------------------------------- 2 ----------------------------------------------CUGCCCUGGCCCGAGGGA-------------- 27 0,-4 ----------------------------------------------CUGCCCUGGCCCGAGGGAa------------- 6 0,-4 ----------------------------------------------CUGCCCUGGCCCGAGGGAaa------------ 4 0,-4 ----------------------------------------------CUGCCCUGGCCCGAGGGAau------------ 2 0,-4 ----------------------------------------------CUGCCCUGGCCCGAGGGAC------------- 43 0,-3 ----------------------------------------------CUGCCCUGGCCCGAGGGACa------------ 2 0,-3 ----------------------------------------------CUGCCCUGGCCCGAGGGACu------------ 2 0,-3 ----------------------------------------------CUGCCCUGGCCCGAGGGACC------------ 20 0,-2 ----------------------------------------------CUGCCCUGGCCCGAGGGACCG----------- 25 0,-1 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGc---------- 12 0,-1 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGu---------- 16 0,-1 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGuu--------- 5 0,-1 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGA---------- 1080 0,0 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGAa--------- 55 0,0 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGAau-------- 9 0,0 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGAg--------- 3 0,0 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGAu--------- 132 0,0 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGAuu-------- 7 0,0 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGAC--------- 710 0,1 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGACa-------- 62 0,1 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGACc-------- 4 0,1 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGACg-------- 2 0,1 ----------------------------------------------CUGCCCUGGCCCGAGGGACCGACU-------- 319 0,2 -----------------------------------------------UGCCCUGGCCCGAGGGAC------------- 2 1,-3 -----------------------------------------------UGCCCUGGCCCGAGGGACC------------ 2 1,-2 -----------------------------------------------UGCCCUGGCCCGAGGGACCGA---------- 96 1,0 -----------------------------------------------UGCCCUGGCCCGAGGGACCGAa--------- 2 1,0 -----------------------------------------------UGCCCUGGCCCGAGGGACCGAC--------- 52 1,1 -----------------------------------------------UGCCCUGGCCCGAGGGACCGACa-------- 2 1,1 -----------------------------------------------UGCCCUGGCCCGAGGGACCGACU-------- 35 1,2 >hsa-mir-875 5p:11-32;3p:45-65 Tumor uuagugguacUAUACCUCAGUUUUAUCAGGUGuucuuaaaaucaCCUGGAAACACUGAGGUUGUGucucacugaac ----------UAUACCUCAGUUUUAUCAGGU--------------------------------------------- 11 0,-1 ----------UAUACCUCAGUUUUAUCAGGUG-------------------------------------------- 6 0,0 ----------UAUACCUCAGUUUUAUCAGGUGU------------------------------------------- 7 0,1 -----------AUACCUCAGUUUUAUCAGGU--------------------------------------------- 2 1,-1 >hsa-mir-876 5p:11-32;3p:50-71 Tumor ugaagugcugUGGAUUUCUUUGUGAAUCACCAuaucuaagcuaauguggUGGUGGUUUACAAAGUAAUUCAuagugcuuca ----------UGGAUUUCUUUGUGAAUCACC-------------------------------------------------- 4 0,-1 ----------UGGAUUUCUUUGUGAAUCACCA------------------------------------------------- 2 0,0 >hsa-mir-877 MA:1-20;mi:66-86 Tumor GUAGAGGAGAUGGCGCAGGGgacacgggcaaagacuuggggguuccugggacccucagacgugugUCCUCUUCUCCCUCCUCCCAG GUAGAGGAGAUGGCGCAG-------------------------------------------------------------------- 2 0,-2 GUAGAGGAGAUGGCGCAGG------------------------------------------------------------------- 2 0,-1 GUAGAGGAGAUGGCGCAGGa------------------------------------------------------------------ 2 0,-1 GUAGAGGAGAUGGCGCAGGaa----------------------------------------------------------------- 2 0,-1 GUAGAGGAGAUGGCGCAGGG------------------------------------------------------------------ 22 0,0 GUAGAGGAGAUGGCGCAGGGa----------------------------------------------------------------- 5 0,0 GUAGAGGAGAUGGCGCAGGGu----------------------------------------------------------------- 2 0,0 GUAGAGGAGAUGGCGCAGGGGA---------------------------------------------------------------- 19 0,2 GUAGAGGAGAUGGCGCAGGGGAu--------------------------------------------------------------- 2 0,2 GUAGAGGAGAUGGCGCAGGGGAC--------------------------------------------------------------- 45 0,3 GUAGAGGAGAUGGCGCAGGGGACu-------------------------------------------------------------- 6 0,3 GUAGAGGAGAUGGCGCAGGGGACA-------------------------------------------------------------- 23 0,4 -----------------------------------------------------------------UCCUCUUCUCCCUCCUCCCAG 2 0,0 -----------------------------------------------------------------UCCUCUUCUCCCUCCUCCCAGa 7 0,0 -----------------------------------------------------------------UCCUCUUCUCCCUCCUCCCAGu 31 0,0 >hsa-mir-885 5p:11-32;3p:43-64 Tumor ccgcacucucUCCAUUACACUACCCUGCCUCUucuccaugagAGGCAGCGGGGUGUAGUGGAUAgagcacgggu ----------UCCAUUACACUACCCUGCCUCU------------------------------------------ 22 0,0 >hsa-mir-887 3pM:48-69 Tumor gugcagauccuugggagcccuguuagacucuggauuuuacacuuggaGUGAACGGGCGCCAUCCCGAGGcuuugcacag -------UCCUUGGGAGCCCUGUUAGAC--------------------------------------------------- 2 ----------------------------------------------AGUGAACGGGCGCCAUCCCGAGa---------- 2 -1,-1 -----------------------------------------------GUGAACGGGCGCCAUCCCG------------- 8 0,-3 -----------------------------------------------GUGAACGGGCGCCAUCCCGA------------ 102 0,-2 -----------------------------------------------GUGAACGGGCGCCAUCCCGAa----------- 4 0,-2 -----------------------------------------------GUGAACGGGCGCCAUCCCGAG----------- 155 0,-1 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGa---------- 60 0,-1 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGaa--------- 2 0,-1 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGu---------- 23 0,-1 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGG---------- 294 0,0 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGa--------- 56 0,0 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGau-------- 2 0,0 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGu--------- 36 0,0 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGuu-------- 4 0,0 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGC--------- 189 0,1 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGCa-------- 14 0,1 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGCau------- 2 0,1 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGCc-------- 2 0,1 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGCU-------- 403 0,2 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGCUa------- 7 0,2 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGCUc------- 2 0,2 -----------------------------------------------GUGAACGGGCGCCAUCCCGAGGCUU------- 144 0,3 ------------------------------------------------UGAACGGGCGCCAUCCCGA------------ 4 1,-2 >hsa-mir-889 3pM:49-69 Tumor gugcuuaaagaauggcuguccguaguauggucucuauauuuaugaugaUUAAUAUCGGACAACCAUUGUuuuaguaucc ------------------------------------------------UUAAUAUCGGACAACCAUUG----------- 6 0,-1 ------------------------------------------------UUAAUAUCGGACAACCAUUGU---------- 117 0,0 ------------------------------------------------UUAAUAUCGGACAACCAUUGUaa-------- 2 0,0 ------------------------------------------------UUAAUAUCGGACAACCAUUGUU--------- 4 0,1 >hsa-mir-9-1 MA:16-38;mi:55-76 Tumor cgggguugguuguuaUCUUUGGUUAUCUAGCUGUAUGAgugguguggagucuucAUAAAGCUAGAUAACCGAAAGUaaaaauaacccca ---------------UCUUUGGUUAUCUAGCUG-------------------------------------------------------- 5 0,-5 ---------------UCUUUGGUUAUCUAGCUGU------------------------------------------------------- 39 0,-4 ---------------UCUUUGGUUAUCUAGCUGUA------------------------------------------------------ 75 0,-3 ---------------UCUUUGGUUAUCUAGCUGUAa----------------------------------------------------- 45 0,-3 ---------------UCUUUGGUUAUCUAGCUGUAU----------------------------------------------------- 1082 0,-2 ---------------UCUUUGGUUAUCUAGCUGUAUa---------------------------------------------------- 6 0,-2 ---------------UCUUUGGUUAUCUAGCUGUAUaa--------------------------------------------------- 4 0,-2 ---------------UCUUUGGUUAUCUAGCUGUAUu---------------------------------------------------- 22 0,-2 ---------------UCUUUGGUUAUCUAGCUGUAUG---------------------------------------------------- 1256 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGc--------------------------------------------------- 17 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGg--------------------------------------------------- 2 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGu--------------------------------------------------- 241 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGA--------------------------------------------------- 4027 0,0 ---------------UCUUUGGUUAUCUAGCUGUAUGAa-------------------------------------------------- 15 0,0 ---------------UCUUUGGUUAUCUAGCUGUAUGAu-------------------------------------------------- 17 0,0 ----------------CUUUGGUUAUCUAGCUGU------------------------------------------------------- 5 1,-4 ----------------CUUUGGUUAUCUAGCUGUAU----------------------------------------------------- 15 1,-2 ----------------CUUUGGUUAUCUAGCUGUAUG---------------------------------------------------- 32 1,-1 ----------------CUUUGGUUAUCUAGCUGUAUGc--------------------------------------------------- 4 1,-1 ----------------CUUUGGUUAUCUAGCUGUAUGu--------------------------------------------------- 2 1,-1 ----------------CUUUGGUUAUCUAGCUGUAUGA--------------------------------------------------- 498 1,0 ----------------CUUUGGUUAUCUAGCUGUAUGAa-------------------------------------------------- 7 1,0 -----------------UUUGGUUAUCUAGCUGUAUGA--------------------------------------------------- 57 2,0 -----------------UUUGGUUAUCUAGCUGUAUGAG-------------------------------------------------- 5 2,1 ------------------------------------------------------AUAAAGCUAGAUAACCGA----------------- 2 0,-4 ------------------------------------------------------AUAAAGCUAGAUAACCGAA---------------- 2 0,-3 ------------------------------------------------------AUAAAGCUAGAUAACCGAAA--------------- 2 0,-2 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAG-------------- 29 0,-1 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGa------------- 2 0,-1 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGg------------- 2 0,-1 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGU------------- 761 0,0 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGUu------------ 13 0,0 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGUA------------ 75 0,1 -------------------------------------------------------UAAAGCUAGAUAACCGAA---------------- 2 1,-3 -------------------------------------------------------UAAAGCUAGAUAACCGAAAG-------------- 5 1,-1 -------------------------------------------------------UAAAGCUAGAUAACCGAAAGU------------- 142 1,0 -------------------------------------------------------UAAAGCUAGAUAACCGAAAGUA------------ 179 1,1 -------------------------------------------------------UAAAGCUAGAUAACCGAAAGUAu----------- 18 1,1 -------------------------------------------------------UAAAGCUAGAUAACCGAAAGUAA----------- 24 1,2 --------------------------------------------------------AAAGCUAGAUAACCGAAAGUA------------ 7 2,1 >hsa-mir-9-2 MA:16-38;mi:53-74 Tumor ggaagcgaguuguuaUCUUUGGUUAUCUAGCUGUAUGAguguauuggucuucAUAAAGCUAGAUAACCGAAAGUaaaaacuccuuca ---------------UCUUUGGUUAUCUAGCUG------------------------------------------------------ 5 0,-5 ---------------UCUUUGGUUAUCUAGCUGU----------------------------------------------------- 39 0,-4 ---------------UCUUUGGUUAUCUAGCUGUA---------------------------------------------------- 75 0,-3 ---------------UCUUUGGUUAUCUAGCUGUAa--------------------------------------------------- 45 0,-3 ---------------UCUUUGGUUAUCUAGCUGUAU--------------------------------------------------- 1082 0,-2 ---------------UCUUUGGUUAUCUAGCUGUAUa-------------------------------------------------- 6 0,-2 ---------------UCUUUGGUUAUCUAGCUGUAUaa------------------------------------------------- 4 0,-2 ---------------UCUUUGGUUAUCUAGCUGUAUu-------------------------------------------------- 22 0,-2 ---------------UCUUUGGUUAUCUAGCUGUAUG-------------------------------------------------- 1256 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGc------------------------------------------------- 17 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGg------------------------------------------------- 2 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGu------------------------------------------------- 241 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGA------------------------------------------------- 4027 0,0 ---------------UCUUUGGUUAUCUAGCUGUAUGAa------------------------------------------------ 15 0,0 ---------------UCUUUGGUUAUCUAGCUGUAUGAu------------------------------------------------ 17 0,0 ----------------CUUUGGUUAUCUAGCUGU----------------------------------------------------- 5 1,-4 ----------------CUUUGGUUAUCUAGCUGUAU--------------------------------------------------- 15 1,-2 ----------------CUUUGGUUAUCUAGCUGUAUG-------------------------------------------------- 32 1,-1 ----------------CUUUGGUUAUCUAGCUGUAUGc------------------------------------------------- 4 1,-1 ----------------CUUUGGUUAUCUAGCUGUAUGu------------------------------------------------- 2 1,-1 ----------------CUUUGGUUAUCUAGCUGUAUGA------------------------------------------------- 498 1,0 ----------------CUUUGGUUAUCUAGCUGUAUGAa------------------------------------------------ 7 1,0 -----------------UUUGGUUAUCUAGCUGUAUGA------------------------------------------------- 57 2,0 -----------------UUUGGUUAUCUAGCUGUAUGAG------------------------------------------------ 5 2,1 ----------------------------------------------------AUAAAGCUAGAUAACCGA----------------- 2 0,-4 ----------------------------------------------------AUAAAGCUAGAUAACCGAA---------------- 2 0,-3 ----------------------------------------------------AUAAAGCUAGAUAACCGAAA--------------- 2 0,-2 ----------------------------------------------------AUAAAGCUAGAUAACCGAAAG-------------- 29 0,-1 ----------------------------------------------------AUAAAGCUAGAUAACCGAAAGa------------- 2 0,-1 ----------------------------------------------------AUAAAGCUAGAUAACCGAAAGg------------- 2 0,-1 ----------------------------------------------------AUAAAGCUAGAUAACCGAAAGU------------- 761 0,0 ----------------------------------------------------AUAAAGCUAGAUAACCGAAAGUu------------ 13 0,0 ----------------------------------------------------AUAAAGCUAGAUAACCGAAAGUA------------ 75 0,1 -----------------------------------------------------UAAAGCUAGAUAACCGAA---------------- 2 1,-3 -----------------------------------------------------UAAAGCUAGAUAACCGAAAG-------------- 5 1,-1 -----------------------------------------------------UAAAGCUAGAUAACCGAAAGU------------- 142 1,0 -----------------------------------------------------UAAAGCUAGAUAACCGAAAGUA------------ 179 1,1 -----------------------------------------------------UAAAGCUAGAUAACCGAAAGUAu----------- 18 1,1 -----------------------------------------------------UAAAGCUAGAUAACCGAAAGUAA----------- 24 1,2 ------------------------------------------------------AAAGCUAGAUAACCGAAAGUA------------ 7 2,1 >hsa-mir-9-3 MA:16-38;mi:55-76 Tumor ggaggcccguuucucUCUUUGGUUAUCUAGCUGUAUGAgugccacagagccgucAUAAAGCUAGAUAACCGAAAGUagaaaugauucuca ---------------UCUUUGGUUAUCUAGCUG--------------------------------------------------------- 5 0,-5 ---------------UCUUUGGUUAUCUAGCUGU-------------------------------------------------------- 39 0,-4 ---------------UCUUUGGUUAUCUAGCUGUA------------------------------------------------------- 75 0,-3 ---------------UCUUUGGUUAUCUAGCUGUAa------------------------------------------------------ 45 0,-3 ---------------UCUUUGGUUAUCUAGCUGUAU------------------------------------------------------ 1082 0,-2 ---------------UCUUUGGUUAUCUAGCUGUAUa----------------------------------------------------- 6 0,-2 ---------------UCUUUGGUUAUCUAGCUGUAUaa---------------------------------------------------- 4 0,-2 ---------------UCUUUGGUUAUCUAGCUGUAUu----------------------------------------------------- 22 0,-2 ---------------UCUUUGGUUAUCUAGCUGUAUG----------------------------------------------------- 1256 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGc---------------------------------------------------- 17 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGg---------------------------------------------------- 2 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGu---------------------------------------------------- 241 0,-1 ---------------UCUUUGGUUAUCUAGCUGUAUGA---------------------------------------------------- 4027 0,0 ---------------UCUUUGGUUAUCUAGCUGUAUGAa--------------------------------------------------- 15 0,0 ---------------UCUUUGGUUAUCUAGCUGUAUGAu--------------------------------------------------- 17 0,0 ----------------CUUUGGUUAUCUAGCUGU-------------------------------------------------------- 5 1,-4 ----------------CUUUGGUUAUCUAGCUGUAU------------------------------------------------------ 15 1,-2 ----------------CUUUGGUUAUCUAGCUGUAUG----------------------------------------------------- 32 1,-1 ----------------CUUUGGUUAUCUAGCUGUAUGc---------------------------------------------------- 4 1,-1 ----------------CUUUGGUUAUCUAGCUGUAUGu---------------------------------------------------- 2 1,-1 ----------------CUUUGGUUAUCUAGCUGUAUGA---------------------------------------------------- 498 1,0 ----------------CUUUGGUUAUCUAGCUGUAUGAa--------------------------------------------------- 7 1,0 -----------------UUUGGUUAUCUAGCUGUAUGA---------------------------------------------------- 57 2,0 -----------------UUUGGUUAUCUAGCUGUAUGAG--------------------------------------------------- 5 2,1 ------------------------------------------------------AUAAAGCUAGAUAACCGA------------------ 2 0,-4 ------------------------------------------------------AUAAAGCUAGAUAACCGAA----------------- 2 0,-3 ------------------------------------------------------AUAAAGCUAGAUAACCGAAA---------------- 2 0,-2 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAG--------------- 29 0,-1 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGa-------------- 2 0,-1 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGg-------------- 2 0,-1 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGU-------------- 761 0,0 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGUu------------- 13 0,0 ------------------------------------------------------AUAAAGCUAGAUAACCGAAAGUA------------- 75 0,1 -------------------------------------------------------UAAAGCUAGAUAACCGAA----------------- 2 1,-3 -------------------------------------------------------UAAAGCUAGAUAACCGAAAG--------------- 5 1,-1 -------------------------------------------------------UAAAGCUAGAUAACCGAAAGU-------------- 142 1,0 -------------------------------------------------------UAAAGCUAGAUAACCGAAAGUA------------- 179 1,1 -------------------------------------------------------UAAAGCUAGAUAACCGAAAGUAu------------ 18 1,1 --------------------------------------------------------AAAGCUAGAUAACCGAAAGUA------------- 7 2,1 >hsa-mir-92a-1 mi:11-33;MA:48-69 Tumor cuuucuacacAGGUUGGGAUCGGUUGCAAUGCUguguuucuguauggUAUUGCACUUGUCCCGGCCUGUugaguuugg ----------AGGUUGGGAUCGGUUGCAA------------------------------------------------- 2 0,-4 ----------AGGUUGGGAUCGGUUGCAAUG----------------------------------------------- 2 0,-2 ----------AGGUUGGGAUCGGUUGCAAUGC---------------------------------------------- 19 0,-1 ----------AGGUUGGGAUCGGUUGCAAUGCU--------------------------------------------- 327 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGC------------- 172 0,-4 -----------------------------------------------UAUUGCACUUGUCCCGGCa------------ 31 0,-4 -----------------------------------------------UAUUGCACUUGUCCCGGCaa----------- 35 0,-4 -----------------------------------------------UAUUGCACUUGUCCCGGCau----------- 11 0,-4 -----------------------------------------------UAUUGCACUUGUCCCGGCC------------ 208 0,-3 -----------------------------------------------UAUUGCACUUGUCCCGGCCa----------- 9 0,-3 -----------------------------------------------UAUUGCACUUGUCCCGGCCaa---------- 4 0,-3 -----------------------------------------------UAUUGCACUUGUCCCGGCCau---------- 12 0,-3 -----------------------------------------------UAUUGCACUUGUCCCGGCCU----------- 691 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUa---------- 36 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUaa--------- 78 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUau--------- 142 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUc---------- 2 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUu---------- 105 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUuu--------- 276 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUG---------- 1399 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGa--------- 1796 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGaa-------- 330 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGau-------- 136 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGc--------- 149 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGg--------- 58 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGU--------- 36071 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUa-------- 4979 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUaa------- 2254 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUau------- 1637 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUc-------- 40 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUU-------- 4198 0,1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUUa------- 244 0,1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUUaa------ 15 0,1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUUau------ 85 0,1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUUu------- 767 0,1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUUuu------ 105 0,1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUUG------- 10 0,2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUUGu------ 5 0,2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUUGA------ 4 0,3 ------------------------------------------------AUUGCACUUGUCCCGGCC------------ 2 1,-3 ------------------------------------------------AUUGCACUUGUCCCGGCCU----------- 10 1,-2 ------------------------------------------------AUUGCACUUGUCCCGGCCUau--------- 7 1,-2 ------------------------------------------------AUUGCACUUGUCCCGGCCUuu--------- 8 1,-2 ------------------------------------------------AUUGCACUUGUCCCGGCCUG---------- 47 1,-1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGa--------- 61 1,-1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGaa-------- 16 1,-1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGau-------- 4 1,-1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGc--------- 2 1,-1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGU--------- 2399 1,0 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUa-------- 247 1,0 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUaa------- 122 1,0 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUau------- 49 1,0 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUU-------- 282 1,1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUUa------- 17 1,1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUUu------- 50 1,1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUUuu------ 6 1,1 -------------------------------------------------UUGCACUUGUCCCGGCCUGU--------- 8 2,0 -------------------------------------------------UUGCACUUGUCCCGGCCUGUau------- 2 2,0 -------------------------------------------------UUGCACUUGUCCCGGCCUGUUu------- 2 2,1 >hsa-mir-92a-2 mi:9-30;MA:48-69 Tumor ucaucccuGGGUGGGGAUUUGUUGCAUUACuuguguucuauauaaagUAUUGCACUUGUCCCGGCCUGUggaaga -----------------------------------------------UAUUGCACUUGUCCCGGC---------- 172 0,-4 -----------------------------------------------UAUUGCACUUGUCCCGGCa--------- 31 0,-4 -----------------------------------------------UAUUGCACUUGUCCCGGCaa-------- 35 0,-4 -----------------------------------------------UAUUGCACUUGUCCCGGCau-------- 11 0,-4 -----------------------------------------------UAUUGCACUUGUCCCGGCC--------- 208 0,-3 -----------------------------------------------UAUUGCACUUGUCCCGGCCa-------- 9 0,-3 -----------------------------------------------UAUUGCACUUGUCCCGGCCaa------- 4 0,-3 -----------------------------------------------UAUUGCACUUGUCCCGGCCau------- 12 0,-3 -----------------------------------------------UAUUGCACUUGUCCCGGCCU-------- 691 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUa------- 36 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUaa------ 78 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUau------ 142 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUc------- 2 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUu------- 105 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUuu------ 276 0,-2 -----------------------------------------------UAUUGCACUUGUCCCGGCCUG------- 1399 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGa------ 1796 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGaa----- 330 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGau----- 136 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGc------ 149 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGg------ 58 0,-1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGU------ 36071 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUa----- 4979 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUaa---- 2254 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUau---- 1637 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUc----- 40 0,0 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUG----- 74 0,1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUGa---- 118 0,1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUGau--- 2 0,1 -----------------------------------------------UAUUGCACUUGUCCCGGCCUGUGu---- 41 0,1 ------------------------------------------------AUUGCACUUGUCCCGGCC--------- 2 1,-3 ------------------------------------------------AUUGCACUUGUCCCGGCCU-------- 10 1,-2 ------------------------------------------------AUUGCACUUGUCCCGGCCUau------ 7 1,-2 ------------------------------------------------AUUGCACUUGUCCCGGCCUuu------ 8 1,-2 ------------------------------------------------AUUGCACUUGUCCCGGCCUG------- 47 1,-1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGa------ 61 1,-1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGaa----- 16 1,-1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGau----- 4 1,-1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGc------ 2 1,-1 ------------------------------------------------AUUGCACUUGUCCCGGCCUGU------ 2399 1,0 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUa----- 247 1,0 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUaa---- 122 1,0 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUau---- 49 1,0 ------------------------------------------------AUUGCACUUGUCCCGGCCUGUGa---- 4 1,1 -------------------------------------------------UUGCACUUGUCCCGGCCUGU------ 8 2,0 -------------------------------------------------UUGCACUUGUCCCGGCCUGUau---- 2 2,0 >hsa-mir-92b mi:20-41;MA:61-82 Tumor cgggccccgggcgggcgggAGGGACGGGACGCGGUGCAGUGuuguuuuuucccccgccaaUAUUGCACUCGUCCCGGCCUCCggcccccccggccc -------------------AGGGACGGGACGCGGUGCA---------------------------------------------------------- 4 0,-3 -------------------AGGGACGGGACGCGGUGCAG--------------------------------------------------------- 4 0,-2 -------------------AGGGACGGGACGCGGUGCAGU-------------------------------------------------------- 2 0,-1 -------------------AGGGACGGGACGCGGUGCAGUG------------------------------------------------------- 3 0,0 -------------------AGGGACGGGACGCGGUGCAGUGU------------------------------------------------------ 29 0,1 -------------------AGGGACGGGACGCGGUGCAGUGUU----------------------------------------------------- 36 0,2 -------------------AGGGACGGGACGCGGUGCAGUGUUu---------------------------------------------------- 2 0,2 -----------------------------------------------------------AUAUUGCACUCGUCCCGGCC----------------- 2 -1,-3 -----------------------------------------------------------AUAUUGCACUCGUCCCGGCCUa--------------- 2 -1,-2 -----------------------------------------------------------AUAUUGCACUCGUCCCGGCCUCC-------------- 4 -1,0 ------------------------------------------------------------UAUUGCACUCGUCCCGGC------------------ 29 0,-4 ------------------------------------------------------------UAUUGCACUCGUCCCGGCa----------------- 5 0,-4 ------------------------------------------------------------UAUUGCACUCGUCCCGGCaa---------------- 33 0,-4 ------------------------------------------------------------UAUUGCACUCGUCCCGGCau---------------- 2 0,-4 ------------------------------------------------------------UAUUGCACUCGUCCCGGCu----------------- 4 0,-4 ------------------------------------------------------------UAUUGCACUCGUCCCGGCC----------------- 100 0,-3 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCa---------------- 26 0,-3 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCaa--------------- 4 0,-3 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCau--------------- 4 0,-3 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCU---------------- 616 0,-2 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUa--------------- 17 0,-2 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUaa-------------- 39 0,-2 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUau-------------- 39 0,-2 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUu--------------- 97 0,-2 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUuu-------------- 85 0,-2 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUC--------------- 343 0,-1 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUCa-------------- 105 0,-1 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUCaa------------- 11 0,-1 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUCau------------- 11 0,-1 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUCu-------------- 233 0,-1 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUCuu------------- 25 0,-1 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUCC-------------- 882 0,0 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUCCa------------- 35 0,0 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUCCau------------ 18 0,0 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUCCu------------- 183 0,0 ------------------------------------------------------------UAUUGCACUCGUCCCGGCCUCCuu------------ 34 0,0 -------------------------------------------------------------AUUGCACUCGUCCCGGCCU---------------- 14 1,-2 -------------------------------------------------------------AUUGCACUCGUCCCGGCCUC--------------- 8 1,-1 -------------------------------------------------------------AUUGCACUCGUCCCGGCCUCa-------------- 2 1,-1 -------------------------------------------------------------AUUGCACUCGUCCCGGCCUCu-------------- 2 1,-1 -------------------------------------------------------------AUUGCACUCGUCCCGGCCUCC-------------- 29 1,0 -------------------------------------------------------------AUUGCACUCGUCCCGGCCUCCa------------- 2 1,0 -------------------------------------------------------------AUUGCACUCGUCCCGGCCUCCu------------- 7 1,0 -------------------------------------------------------------AUUGCACUCGUCCCGGCCUCCuu------------ 2 1,0 >hsa-mir-93 MA:11-33;mi:50-71 Tumor cugggggcucCAAAGUGCUGUUCGUGCAGGUAGugugauuacccaaccuACUGCUGAGCUAGCACUUCCCGagcccccgg --------UCCAAAGUGCUGUUCGUGCAGGUAG----------------------------------------------- 2 -2,0 ---------CCAAAGUGCUGUUCGUGCAGGUA------------------------------------------------ 2 -1,-1 ---------CCAAAGUGCUGUUCGUGCAGGUAa----------------------------------------------- 2 -1,-1 ---------CCAAAGUGCUGUUCGUGCAGGUAG----------------------------------------------- 32 -1,0 ----------CAAAGUGCUGUUCGUGCA---------------------------------------------------- 590 0,-5 ----------CAAAGUGCUGUUCGUGCAa--------------------------------------------------- 32 0,-5 ----------CAAAGUGCUGUUCGUGCAu--------------------------------------------------- 6 0,-5 ----------CAAAGUGCUGUUCGUGCAG--------------------------------------------------- 1143 0,-4 ----------CAAAGUGCUGUUCGUGCAGa-------------------------------------------------- 10 0,-4 ----------CAAAGUGCUGUUCGUGCAGau------------------------------------------------- 8 0,-4 ----------CAAAGUGCUGUUCGUGCAGu-------------------------------------------------- 18 0,-4 ----------CAAAGUGCUGUUCGUGCAGuu------------------------------------------------- 15 0,-4 ----------CAAAGUGCUGUUCGUGCAGG-------------------------------------------------- 2235 0,-3 ----------CAAAGUGCUGUUCGUGCAGGa------------------------------------------------- 329 0,-3 ----------CAAAGUGCUGUUCGUGCAGGaa------------------------------------------------ 141 0,-3 ----------CAAAGUGCUGUUCGUGCAGGau------------------------------------------------ 15 0,-3 ----------CAAAGUGCUGUUCGUGCAGGc------------------------------------------------- 7 0,-3 ----------CAAAGUGCUGUUCGUGCAGGg------------------------------------------------- 18 0,-3 ----------CAAAGUGCUGUUCGUGCAGGU------------------------------------------------- 11598 0,-2 ----------CAAAGUGCUGUUCGUGCAGGUc------------------------------------------------ 46 0,-2 ----------CAAAGUGCUGUUCGUGCAGGUg------------------------------------------------ 20 0,-2 ----------CAAAGUGCUGUUCGUGCAGGUu------------------------------------------------ 599 0,-2 ----------CAAAGUGCUGUUCGUGCAGGUuu----------------------------------------------- 232 0,-2 ----------CAAAGUGCUGUUCGUGCAGGUA------------------------------------------------ 16005 0,-1 ----------CAAAGUGCUGUUCGUGCAGGUAa----------------------------------------------- 7594 0,-1 ----------CAAAGUGCUGUUCGUGCAGGUAaa---------------------------------------------- 232 0,-1 ----------CAAAGUGCUGUUCGUGCAGGUAau---------------------------------------------- 171 0,-1 ----------CAAAGUGCUGUUCGUGCAGGUAc----------------------------------------------- 107 0,-1 ----------CAAAGUGCUGUUCGUGCAGGUAu----------------------------------------------- 8388 0,-1 ----------CAAAGUGCUGUUCGUGCAGGUAuu---------------------------------------------- 244 0,-1 ----------CAAAGUGCUGUUCGUGCAGGUAG----------------------------------------------- 89770 0,0 ----------CAAAGUGCUGUUCGUGCAGGUAGa---------------------------------------------- 3431 0,0 ----------CAAAGUGCUGUUCGUGCAGGUAGaa--------------------------------------------- 112 0,0 ----------CAAAGUGCUGUUCGUGCAGGUAGau--------------------------------------------- 32 0,0 ----------CAAAGUGCUGUUCGUGCAGGUAGc---------------------------------------------- 11 0,0 ----------CAAAGUGCUGUUCGUGCAGGUAGg---------------------------------------------- 28 0,0 ----------CAAAGUGCUGUUCGUGCAGGUAGU---------------------------------------------- 6831 0,1 ----------CAAAGUGCUGUUCGUGCAGGUAGUa--------------------------------------------- 30 0,1 ----------CAAAGUGCUGUUCGUGCAGGUAGUu--------------------------------------------- 78 0,1 ----------CAAAGUGCUGUUCGUGCAGGUAGUG--------------------------------------------- 2 0,2 -----------AAAGUGCUGUUCGUGCAG--------------------------------------------------- 13 1,-4 -----------AAAGUGCUGUUCGUGCAGG-------------------------------------------------- 40 1,-3 -----------AAAGUGCUGUUCGUGCAGGa------------------------------------------------- 2 1,-3 -----------AAAGUGCUGUUCGUGCAGGaa------------------------------------------------ 2 1,-3 -----------AAAGUGCUGUUCGUGCAGGU------------------------------------------------- 406 1,-2 -----------AAAGUGCUGUUCGUGCAGGUc------------------------------------------------ 2 1,-2 -----------AAAGUGCUGUUCGUGCAGGUu------------------------------------------------ 4 1,-2 -----------AAAGUGCUGUUCGUGCAGGUA------------------------------------------------ 676 1,-1 -----------AAAGUGCUGUUCGUGCAGGUAa----------------------------------------------- 287 1,-1 -----------AAAGUGCUGUUCGUGCAGGUAaa---------------------------------------------- 4 1,-1 -----------AAAGUGCUGUUCGUGCAGGUAau---------------------------------------------- 5 1,-1 -----------AAAGUGCUGUUCGUGCAGGUAu----------------------------------------------- 334 1,-1 -----------AAAGUGCUGUUCGUGCAGGUAG----------------------------------------------- 3696 1,0 -----------AAAGUGCUGUUCGUGCAGGUAGa---------------------------------------------- 222 1,0 -----------AAAGUGCUGUUCGUGCAGGUAGau--------------------------------------------- 2 1,0 -----------AAAGUGCUGUUCGUGCAGGUAGU---------------------------------------------- 390 1,1 ------------AAGUGCUGUUCGUGCAGGU------------------------------------------------- 4 2,-2 ------------AAGUGCUGUUCGUGCAGGUA------------------------------------------------ 5 2,-1 ------------AAGUGCUGUUCGUGCAGGUAa----------------------------------------------- 2 2,-1 ------------AAGUGCUGUUCGUGCAGGUAG----------------------------------------------- 37 2,0 ------------------------------------------------UACUGCUGAGCUAGCACUUCC----------- 3 -1,-2 ------------------------------------------------UACUGCUGAGCUAGCACUUCCC---------- 3 -1,-1 -------------------------------------------------ACUGCUGAGCUAGCACUU------------- 13 0,-4 -------------------------------------------------ACUGCUGAGCUAGCACUUC------------ 39 0,-3 -------------------------------------------------ACUGCUGAGCUAGCACUUCa----------- 2 0,-3 -------------------------------------------------ACUGCUGAGCUAGCACUUCu----------- 10 0,-3 -------------------------------------------------ACUGCUGAGCUAGCACUUCuu---------- 2 0,-3 -------------------------------------------------ACUGCUGAGCUAGCACUUCC----------- 101 0,-2 -------------------------------------------------ACUGCUGAGCUAGCACUUCCC---------- 46 0,-1 -------------------------------------------------ACUGCUGAGCUAGCACUUCCCa--------- 4 0,-1 -------------------------------------------------ACUGCUGAGCUAGCACUUCCCu--------- 2 0,-1 -------------------------------------------------ACUGCUGAGCUAGCACUUCCCG--------- 422 0,0 -------------------------------------------------ACUGCUGAGCUAGCACUUCCCGu-------- 270 0,0 -------------------------------------------------ACUGCUGAGCUAGCACUUCCCGuu------- 19 0,0 -------------------------------------------------ACUGCUGAGCUAGCACUUCCCGA-------- 944 0,1 -------------------------------------------------ACUGCUGAGCUAGCACUUCCCGAa------- 2 0,1 -------------------------------------------------ACUGCUGAGCUAGCACUUCCCGAu------- 18 0,1 -------------------------------------------------ACUGCUGAGCUAGCACUUCCCGAuu------ 2 0,1 --------------------------------------------------CUGCUGAGCUAGCACUUCCCG--------- 3 1,0 --------------------------------------------------CUGCUGAGCUAGCACUUCCCGA-------- 10 1,1 >hsa-mir-934 5pM:15-36 Tumor agaaauaaggcuucUGUCUACUACUGGAGACACUGGuaguauaaaacccagagucuccaguaauggacgggagccuuauuucu -------------CUGUCUACUACUGGAGACACU------------------------------------------------- 3 -1,-2 -------------CUGUCUACUACUGGAGACACUGG----------------------------------------------- 2 -1,0 --------------UGUCUACUACUGGAGACA--------------------------------------------------- 4 0,-4 --------------UGUCUACUACUGGAGACAau------------------------------------------------- 2 0,-4 --------------UGUCUACUACUGGAGACAC-------------------------------------------------- 15 0,-3 --------------UGUCUACUACUGGAGACACU------------------------------------------------- 721 0,-2 --------------UGUCUACUACUGGAGACACUa------------------------------------------------ 2 0,-2 --------------UGUCUACUACUGGAGACACUu------------------------------------------------ 5 0,-2 --------------UGUCUACUACUGGAGACACUG------------------------------------------------ 601 0,-1 --------------UGUCUACUACUGGAGACACUGa----------------------------------------------- 37 0,-1 --------------UGUCUACUACUGGAGACACUGaa---------------------------------------------- 3 0,-1 --------------UGUCUACUACUGGAGACACUGu----------------------------------------------- 60 0,-1 --------------UGUCUACUACUGGAGACACUGG----------------------------------------------- 1238 0,0 --------------UGUCUACUACUGGAGACACUGGa---------------------------------------------- 498 0,0 --------------UGUCUACUACUGGAGACACUGGaa--------------------------------------------- 103 0,0 --------------UGUCUACUACUGGAGACACUGGau--------------------------------------------- 21 0,0 --------------UGUCUACUACUGGAGACACUGGc---------------------------------------------- 2 0,0 --------------UGUCUACUACUGGAGACACUGGU---------------------------------------------- 122 0,1 --------------UGUCUACUACUGGAGACACUGGUu--------------------------------------------- 15 0,1 --------------UGUCUACUACUGGAGACACUGGUA--------------------------------------------- 10 0,2 ---------------GUCUACUACUGGAGACACU------------------------------------------------- 13 1,-2 ---------------GUCUACUACUGGAGACACUG------------------------------------------------ 13 1,-1 ---------------GUCUACUACUGGAGACACUGG----------------------------------------------- 29 1,0 ---------------GUCUACUACUGGAGACACUGGa---------------------------------------------- 5 1,0 ---------------GUCUACUACUGGAGACACUGGaa--------------------------------------------- 2 1,0 ---------------GUCUACUACUGGAGACACUGGUA--------------------------------------------- 2 1,2 -------------------------------------------------AGAGUCUCCAGUAAUGGACG-------------- 5 -------------------------------------------------AGAGUCUCCAGUAAUGGACGG------------- 2 -------------------------------------------------AGAGUCUCCAGUAAUGGACGGa------------ 2 -------------------------------------------------AGAGUCUCCAGUAAUGGACGGG------------ 17 -------------------------------------------------AGAGUCUCCAGUAAUGGACGGGu----------- 7 -------------------------------------------------AGAGUCUCCAGUAAUGGACGGGA----------- 3 --------------------------------------------------GAGUCUCCAGUAAUGGACGGGu----------- 11 --------------------------------------------------GAGUCUCCAGUAAUGGACGGGA----------- 52 --------------------------------------------------GAGUCUCCAGUAAUGGACGGGAa---------- 6 --------------------------------------------------GAGUCUCCAGUAAUGGACGGGAau--------- 2 --------------------------------------------------GAGUCUCCAGUAAUGGACGGGAu---------- 6 >hsa-mir-935 3pM:56-78 Tumor ggcgggggcgcgggcggcaguggcgggagcggccccucggccauccuccgucugcCCAGUUACCGCUUCCGCUACCGCcgccgcucccgcu -------------------------------------------------------CCAGUUACCGCUUCCGCUACCG-------------- 13 0,-1 --------------------------------------------------------CAGUUACCGCUUCCGCUACC--------------- 7 1,-2 --------------------------------------------------------CAGUUACCGCUUCCGCUACCG-------------- 88 1,-1 --------------------------------------------------------CAGUUACCGCUUCCGCUACCGu------------- 5 1,-1 --------------------------------------------------------CAGUUACCGCUUCCGCUACCGC------------- 33 1,0 --------------------------------------------------------CAGUUACCGCUUCCGCUACCGCa------------ 2 1,0 ---------------------------------------------------------AGUUACCGCUUCCGCUACCG-------------- 2 2,-1 ---------------------------------------------------------AGUUACCGCUUCCGCUACCGC------------- 3 2,0 >hsa-mir-937 3pM:51-72 Tumor agcacugcccccggugagucaggguggggcuggcccccugcuucgugcccAUCCGCGCUCUGACUCUCUGCCcaccugcaggagcu --------------------------------------------------AUCCGCGCUCUGACUCUCUGu--------------- 2 0,-2 --------------------------------------------------AUCCGCGCUCUGACUCUCUGC--------------- 12 0,-1 --------------------------------------------------AUCCGCGCUCUGACUCUCUGCC-------------- 6 0,0 >hsa-mir-939 5pM:15-38 Tumor ugugggcagggcccUGGGGAGCUGAGGCUCUGGGGGUGgccggggcugacccugggccucugcuccccagugucugaccgcg --------------UGGGGAGCUGAGGCUCUGGGGGUGu------------------------------------------- 2 0,0 -------------------------------------------------CCCUGGGCCUCUGCUCCCCAGU----------- 9 >hsa-mir-940 3pM:60-80 Tumor gugaggugugggcccggccccaggagcggggccugggcagccccguguguugaggaaggAAGGCAGGGCCCCCGCUCCCCgggccugaccccac -----------------------------------------------------------AAGGCAGGGCCCCCGCUCC---------------- 5 0,-2 -----------------------------------------------------------AAGGCAGGGCCCCCGCUCCC--------------- 9 0,-1 -----------------------------------------------------------AAGGCAGGGCCCCCGCUCCCuu------------- 2 0,-1 -----------------------------------------------------------AAGGCAGGGCCCCCGCUCCCC-------------- 52 0,0 -----------------------------------------------------------AAGGCAGGGCCCCCGCUCCCCu------------- 128 0,0 -----------------------------------------------------------AAGGCAGGGCCCCCGCUCCCCuu------------ 31 0,0 -----------------------------------------------------------AAGGCAGGGCCCCCGCUCCCCGu------------ 2 0,1 -----------------------------------------------------------AAGGCAGGGCCCCCGCUCCCCGG------------ 2 0,2 >hsa-mir-941-1 3pM:71-93 Tumor cacggaagaggacacacccggcuguguggacaugugcccagggcccgggacagcgccacggaagaggacgCACCCGGCUGUGUGCACAUGUGCccagggcccgggacagcgccacgg -----------------------------ACAUGUGCCCAGGGCCCGGGACAGC--------------------------------------------------------------- 2 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUG--------------------------- 6 0,-3 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGU-------------------------- 72 0,-2 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUau------------------------ 2 0,-2 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUG------------------------- 227 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGa------------------------ 131 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGu------------------------ 108 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGC------------------------ 752 0,0 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGCa----------------------- 2 0,0 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGCu----------------------- 22 0,0 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUG------------------------- 4 1,-1 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUGa------------------------ 2 1,-1 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUGu------------------------ 2 1,-1 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUGC------------------------ 7 1,0 >hsa-mir-941-2 3pM:71-93 Tumor cacggaagaggacgcacccggcugugugcacaugugcccagggcccgggacagcgccacggaagaggacgCACCCGGCUGUGUGCACAUGUGCccagggcccgggacagcgccacgg --------------CACCCGGCUGUGUGCACAUG----------------------------------------------------------------------------------- 6 --------------CACCCGGCUGUGUGCACAUGU---------------------------------------------------------------------------------- 72 --------------CACCCGGCUGUGUGCACAUGUau-------------------------------------------------------------------------------- 2 --------------CACCCGGCUGUGUGCACAUGUG--------------------------------------------------------------------------------- 227 --------------CACCCGGCUGUGUGCACAUGUGa-------------------------------------------------------------------------------- 131 --------------CACCCGGCUGUGUGCACAUGUGu-------------------------------------------------------------------------------- 108 --------------CACCCGGCUGUGUGCACAUGUGC-------------------------------------------------------------------------------- 752 --------------CACCCGGCUGUGUGCACAUGUGCa------------------------------------------------------------------------------- 2 --------------CACCCGGCUGUGUGCACAUGUGCu------------------------------------------------------------------------------- 22 ---------------ACCCGGCUGUGUGCACAUGUG--------------------------------------------------------------------------------- 4 ---------------ACCCGGCUGUGUGCACAUGUGa-------------------------------------------------------------------------------- 2 ---------------ACCCGGCUGUGUGCACAUGUGu-------------------------------------------------------------------------------- 2 ---------------ACCCGGCUGUGUGCACAUGUGC-------------------------------------------------------------------------------- 7 -----------------------------ACAUGUGCCCAGGGCCCGGGACAGC--------------------------------------------------------------- 2 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUG--------------------------- 6 0,-3 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGU-------------------------- 72 0,-2 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUau------------------------ 2 0,-2 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUG------------------------- 227 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGa------------------------ 131 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGu------------------------ 108 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGC------------------------ 752 0,0 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGCa----------------------- 2 0,0 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGCu----------------------- 22 0,0 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUG------------------------- 4 1,-1 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUGa------------------------ 2 1,-1 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUGu------------------------ 2 1,-1 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUGC------------------------ 7 1,0 >hsa-mir-941-3 3pM:71-93 Tumor cacggaagaggacgcacccggcugugugcacaugugcccagggcccgggacagcgccacggaagaggacgCACCCGGCUGUGUGCACAUGUGCccagggcccgggacagcgccaugg --------------CACCCGGCUGUGUGCACAUG----------------------------------------------------------------------------------- 6 --------------CACCCGGCUGUGUGCACAUGU---------------------------------------------------------------------------------- 72 --------------CACCCGGCUGUGUGCACAUGUau-------------------------------------------------------------------------------- 2 --------------CACCCGGCUGUGUGCACAUGUG--------------------------------------------------------------------------------- 227 --------------CACCCGGCUGUGUGCACAUGUGa-------------------------------------------------------------------------------- 131 --------------CACCCGGCUGUGUGCACAUGUGu-------------------------------------------------------------------------------- 108 --------------CACCCGGCUGUGUGCACAUGUGC-------------------------------------------------------------------------------- 752 --------------CACCCGGCUGUGUGCACAUGUGCa------------------------------------------------------------------------------- 2 --------------CACCCGGCUGUGUGCACAUGUGCu------------------------------------------------------------------------------- 22 ---------------ACCCGGCUGUGUGCACAUGUG--------------------------------------------------------------------------------- 4 ---------------ACCCGGCUGUGUGCACAUGUGa-------------------------------------------------------------------------------- 2 ---------------ACCCGGCUGUGUGCACAUGUGu-------------------------------------------------------------------------------- 2 ---------------ACCCGGCUGUGUGCACAUGUGC-------------------------------------------------------------------------------- 7 -----------------------------ACAUGUGCCCAGGGCCCGGGACAGC--------------------------------------------------------------- 2 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUG--------------------------- 6 0,-3 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGU-------------------------- 72 0,-2 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUau------------------------ 2 0,-2 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUG------------------------- 227 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGa------------------------ 131 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGu------------------------ 108 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGC------------------------ 752 0,0 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGCa----------------------- 2 0,0 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGCu----------------------- 22 0,0 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUG------------------------- 4 1,-1 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUGa------------------------ 2 1,-1 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUGu------------------------ 2 1,-1 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUGC------------------------ 7 1,0 >hsa-mir-941-4 3pM:71-93 Tumor cauggaagaggacgcacccggcugugugcacaugugcccagggcccgggacagcgccacggaagaggacgCACCCGGCUGUGUGCACAUGUGCccagggcccgggacagcgccacgg --------------CACCCGGCUGUGUGCACAUG----------------------------------------------------------------------------------- 6 --------------CACCCGGCUGUGUGCACAUGU---------------------------------------------------------------------------------- 72 --------------CACCCGGCUGUGUGCACAUGUau-------------------------------------------------------------------------------- 2 --------------CACCCGGCUGUGUGCACAUGUG--------------------------------------------------------------------------------- 227 --------------CACCCGGCUGUGUGCACAUGUGa-------------------------------------------------------------------------------- 131 --------------CACCCGGCUGUGUGCACAUGUGu-------------------------------------------------------------------------------- 108 --------------CACCCGGCUGUGUGCACAUGUGC-------------------------------------------------------------------------------- 752 --------------CACCCGGCUGUGUGCACAUGUGCa------------------------------------------------------------------------------- 2 --------------CACCCGGCUGUGUGCACAUGUGCu------------------------------------------------------------------------------- 22 ---------------ACCCGGCUGUGUGCACAUGUG--------------------------------------------------------------------------------- 4 ---------------ACCCGGCUGUGUGCACAUGUGa-------------------------------------------------------------------------------- 2 ---------------ACCCGGCUGUGUGCACAUGUGu-------------------------------------------------------------------------------- 2 ---------------ACCCGGCUGUGUGCACAUGUGC-------------------------------------------------------------------------------- 7 -----------------------------ACAUGUGCCCAGGGCCCGGGACAGC--------------------------------------------------------------- 2 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUG--------------------------- 6 0,-3 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGU-------------------------- 72 0,-2 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUau------------------------ 2 0,-2 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUG------------------------- 227 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGa------------------------ 131 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGu------------------------ 108 0,-1 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGC------------------------ 752 0,0 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGCa----------------------- 2 0,0 ----------------------------------------------------------------------CACCCGGCUGUGUGCACAUGUGCu----------------------- 22 0,0 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUG------------------------- 4 1,-1 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUGa------------------------ 2 1,-1 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUGu------------------------ 2 1,-1 -----------------------------------------------------------------------ACCCGGCUGUGUGCACAUGUGC------------------------ 7 1,0 >hsa-mir-942 5pM:13-34 Tumor auuaggagaguaUCUUCUCUGUUUUGGCCAUGUGuguacucacagccccucacacauggccgaaacagagaaguuacuuuccuaau ------------UCUUCUCUGUUUUGGCCAUGUG---------------------------------------------------- 4 0,0 ------------UCUUCUCUGUUUUGGCCAUGUGa--------------------------------------------------- 2 0,0 ------------UCUUCUCUGUUUUGGCCAUGUGU--------------------------------------------------- 5 0,1 --------------UUCUCUGUUUUGGCCAUGUGU--------------------------------------------------- 24 2,1 --------------UUCUCUGUUUUGGCCAUGUGUG-------------------------------------------------- 9 2,2 --------------UUCUCUGUUUUGGCCAUGUGUGa------------------------------------------------- 6 2,2 --------------UUCUCUGUUUUGGCCAUGUGUGU------------------------------------------------- 5 2,3 ----------------------------------------------------CACAUGGCCGAAACAGAGAAGU------------ 7 >hsa-mir-944 3pM:54-75 Tumor guuccagacacaucucaucugauauacaauauuuucuuaaauuguauaaagagAAAUUAUUGUACAUCGGAUGAGcugugucugggau -----------------------------------------------------AAAUUAUUGUACAUCGGAUGAG------------- 14 0,0 -----------------------------------------------------AAAUUAUUGUACAUCGGAUGAGa------------ 2 0,0 ------------------------------------------------------AAUUAUUGUACAUCGGAUGAGu------------ 2 1,0 >hsa-mir-95 3pM:49-70 Tumor aacacagugggcacucaauaaaugucuguugaauugaaaugcguuacaUUCAACGGGUAUUUAUUGAGCAcccacucugug ------------ACUCAAUAAAUGUCUGUUGA------------------------------------------------- 5 ------------ACUCAAUAAAUGUCUGUUGAA------------------------------------------------ 2 -------------CUCAAUAAAUGUCUGUUGAAa----------------------------------------------- 2 -------------CUCAAUAAAUGUCUGUUGAAUU---------------------------------------------- 2 --------------UCAAUAAAUGUCUGUUGAAU----------------------------------------------- 4 ------------------------------------------------UUCAACGGGUAUUUAUUGAa------------- 2 0,-3 ------------------------------------------------UUCAACGGGUAUUUAUUGAaa------------ 2 0,-3 ------------------------------------------------UUCAACGGGUAUUUAUUGAG------------- 73 0,-2 ------------------------------------------------UUCAACGGGUAUUUAUUGAGa------------ 43 0,-2 ------------------------------------------------UUCAACGGGUAUUUAUUGAGaa----------- 8 0,-2 ------------------------------------------------UUCAACGGGUAUUUAUUGAGC------------ 611 0,-1 ------------------------------------------------UUCAACGGGUAUUUAUUGAGCc----------- 2 0,-1 ------------------------------------------------UUCAACGGGUAUUUAUUGAGCA----------- 559 0,0 ------------------------------------------------UUCAACGGGUAUUUAUUGAGCAa---------- 107 0,0 ------------------------------------------------UUCAACGGGUAUUUAUUGAGCAu---------- 12 0,0 -------------------------------------------------UCAACGGGUAUUUAUUGAGC------------ 19 1,-1 -------------------------------------------------UCAACGGGUAUUUAUUGAGCAa---------- 5 1,0 --------------------------------------------------CAACGGGUAUUUAUUGAGCAa---------- 2 2,0 >hsa-mir-96 MA:9-31;mi:52-73 Tumor uggccgauUUUGGCACUAGCACAUUUUUGCUugugucucuccgcucugagcAAUCAUGUGCAGUGCCAAUAUGggaaa --------UUUGGCACUAGCACAUUU---------------------------------------------------- 33 0,-5 --------UUUGGCACUAGCACAUUUU--------------------------------------------------- 186 0,-4 --------UUUGGCACUAGCACAUUUUa-------------------------------------------------- 2 0,-4 --------UUUGGCACUAGCACAUUUUg-------------------------------------------------- 2 0,-4 --------UUUGGCACUAGCACAUUUUU-------------------------------------------------- 877 0,-3 --------UUUGGCACUAGCACAUUUUUa------------------------------------------------- 4 0,-3 --------UUUGGCACUAGCACAUUUUUu------------------------------------------------- 14 0,-3 --------UUUGGCACUAGCACAUUUUUuu------------------------------------------------ 2 0,-3 --------UUUGGCACUAGCACAUUUUUG------------------------------------------------- 3990 0,-2 --------UUUGGCACUAGCACAUUUUUGa------------------------------------------------ 472 0,-2 --------UUUGGCACUAGCACAUUUUUGaa----------------------------------------------- 11 0,-2 --------UUUGGCACUAGCACAUUUUUGau----------------------------------------------- 47 0,-2 --------UUUGGCACUAGCACAUUUUUGu------------------------------------------------ 345 0,-2 --------UUUGGCACUAGCACAUUUUUGuu----------------------------------------------- 41 0,-2 --------UUUGGCACUAGCACAUUUUUGC------------------------------------------------ 4323 0,-1 --------UUUGGCACUAGCACAUUUUUGCa----------------------------------------------- 148 0,-1 --------UUUGGCACUAGCACAUUUUUGCc----------------------------------------------- 28 0,-1 --------UUUGGCACUAGCACAUUUUUGCU----------------------------------------------- 29759 0,0 --------UUUGGCACUAGCACAUUUUUGCUa---------------------------------------------- 69 0,0 --------UUUGGCACUAGCACAUUUUUGCUg---------------------------------------------- 4 0,0 --------UUUGGCACUAGCACAUUUUUGCUU---------------------------------------------- 205 0,1 --------UUUGGCACUAGCACAUUUUUGCUUu--------------------------------------------- 11 0,1 ---------UUGGCACUAGCACAUUUUU-------------------------------------------------- 2 1,-3 ---------UUGGCACUAGCACAUUUUUG------------------------------------------------- 58 1,-2 ---------UUGGCACUAGCACAUUUUUGC------------------------------------------------ 67 1,-1 ---------UUGGCACUAGCACAUUUUUGCU----------------------------------------------- 569 1,0 ---------UUGGCACUAGCACAUUUUUGCUU---------------------------------------------- 2 1,1 ----------UGGCACUAGCACAUUUUUGCU----------------------------------------------- 22 2,0 --------------------------------------------------CAAUCAUGUGCAGUGCCAAUA------- 11 -1,-2 --------------------------------------------------CAAUCAUGUGCAGUGCCAAUAU------ 25 -1,-1 ---------------------------------------------------AAUCAUGUGCAGUGCCAA--------- 2 0,-4 ---------------------------------------------------AAUCAUGUGCAGUGCCAAU-------- 2 0,-3 ---------------------------------------------------AAUCAUGUGCAGUGCCAAUAUu----- 2 0,-1 >hsa-mir-98 5pM:22-43 Tumor aggauucugcucaugccagggUGAGGUAGUAAGUUGUAUUGUUgugggguagggauauuaggccccaauuagaagauaacuauacaacuuacuacuuucccugguguguggcauauuca ---------------------UGAGGUAGUAAGUUGUAU-------------------------------------------------------------------------------- 2625 0,-4 ---------------------UGAGGUAGUAAGUUGUAUU------------------------------------------------------------------------------- 100 0,-3 ---------------------UGAGGUAGUAAGUUGUAUUa------------------------------------------------------------------------------ 7 0,-3 ---------------------UGAGGUAGUAAGUUGUAUUu------------------------------------------------------------------------------ 5 0,-3 ---------------------UGAGGUAGUAAGUUGUAUUuu----------------------------------------------------------------------------- 2 0,-3 ---------------------UGAGGUAGUAAGUUGUAUUG------------------------------------------------------------------------------ 520 0,-2 ---------------------UGAGGUAGUAAGUUGUAUUGa----------------------------------------------------------------------------- 57 0,-2 ---------------------UGAGGUAGUAAGUUGUAUUGU----------------------------------------------------------------------------- 3623 0,-1 ---------------------UGAGGUAGUAAGUUGUAUUGUa---------------------------------------------------------------------------- 110 0,-1 ---------------------UGAGGUAGUAAGUUGUAUUGUaa--------------------------------------------------------------------------- 32 0,-1 ---------------------UGAGGUAGUAAGUUGUAUUGUc---------------------------------------------------------------------------- 9 0,-1 ---------------------UGAGGUAGUAAGUUGUAUUGUg---------------------------------------------------------------------------- 2 0,-1 ---------------------UGAGGUAGUAAGUUGUAUUGUU---------------------------------------------------------------------------- 14542 0,0 ---------------------UGAGGUAGUAAGUUGUAUUGUUa--------------------------------------------------------------------------- 809 0,0 ---------------------UGAGGUAGUAAGUUGUAUUGUUaa-------------------------------------------------------------------------- 8 0,0 ---------------------UGAGGUAGUAAGUUGUAUUGUUau-------------------------------------------------------------------------- 2 0,0 ---------------------UGAGGUAGUAAGUUGUAUUGUUc--------------------------------------------------------------------------- 2 0,0 ---------------------UGAGGUAGUAAGUUGUAUUGUUu--------------------------------------------------------------------------- 605 0,0 ---------------------UGAGGUAGUAAGUUGUAUUGUUG--------------------------------------------------------------------------- 28 0,1 ----------------------GAGGUAGUAAGUUGUAUUG------------------------------------------------------------------------------ 4 1,-2 ----------------------GAGGUAGUAAGUUGUAUUGU----------------------------------------------------------------------------- 52 1,-1 ----------------------GAGGUAGUAAGUUGUAUUGUU---------------------------------------------------------------------------- 373 1,0 ----------------------GAGGUAGUAAGUUGUAUUGUUa--------------------------------------------------------------------------- 14 1,0 ----------------------GAGGUAGUAAGUUGUAUUGUUu--------------------------------------------------------------------------- 4 1,0 -----------------------AGGUAGUAAGUUGUAUUGUU---------------------------------------------------------------------------- 4 2,0 -------------------------------------------------------------------------------CUAUACAACUUACUACUUU--------------------- 5 -------------------------------------------------------------------------------CUAUACAACUUACUACUUUC-------------------- 22 -------------------------------------------------------------------------------CUAUACAACUUACUACUUUCC------------------- 72 -------------------------------------------------------------------------------CUAUACAACUUACUACUUUCCa------------------ 6 -------------------------------------------------------------------------------CUAUACAACUUACUACUUUCCu------------------ 164 -------------------------------------------------------------------------------CUAUACAACUUACUACUUUCCuu----------------- 4 --------------------------------------------------------------------------------UAUACAACUUACUACUUUC-------------------- 2 --------------------------------------------------------------------------------UAUACAACUUACUACUUUCC------------------- 7 --------------------------------------------------------------------------------UAUACAACUUACUACUUUCCu------------------ 17 --------------------------------------------------------------------------------UAUACAACUUACUACUUUCCuu----------------- 31 >hsa-mir-99a MA:13-34;mi:50-71 Tumor cccauuggcauaAACCCGUAGAUCCGAUCUUGUGgugaaguggaccgcaCAAGCUCGCUUCUAUGGGUCUGugucagugug -----------AAACCCGUAGAUCCGAUCUU-------------------------------------------------- 4 -1,-3 -----------AAACCCGUAGAUCCGAUCUUG------------------------------------------------- 75 -1,-2 -----------AAACCCGUAGAUCCGAUCUUGa------------------------------------------------ 7 -1,-2 -----------AAACCCGUAGAUCCGAUCUUGU------------------------------------------------ 1856 -1,-1 -----------AAACCCGUAGAUCCGAUCUUGUa----------------------------------------------- 8 -1,-1 -----------AAACCCGUAGAUCCGAUCUUGUG----------------------------------------------- 83 -1,0 -----------AAACCCGUAGAUCCGAUCUUGUGa---------------------------------------------- 8 -1,0 -----------AAACCCGUAGAUCCGAUCUUGUGu---------------------------------------------- 14 -1,0 ------------AACCCGUAGAUCCGAUCU--------------------------------------------------- 641 0,-4 ------------AACCCGUAGAUCCGAUCUa-------------------------------------------------- 6 0,-4 ------------AACCCGUAGAUCCGAUCUau------------------------------------------------- 2 0,-4 ------------AACCCGUAGAUCCGAUCUU-------------------------------------------------- 1774 0,-3 ------------AACCCGUAGAUCCGAUCUUa------------------------------------------------- 25 0,-3 ------------AACCCGUAGAUCCGAUCUUaa------------------------------------------------ 2 0,-3 ------------AACCCGUAGAUCCGAUCUUau------------------------------------------------ 138 0,-3 ------------AACCCGUAGAUCCGAUCUUc------------------------------------------------- 2 0,-3 ------------AACCCGUAGAUCCGAUCUUu------------------------------------------------- 44 0,-3 ------------AACCCGUAGAUCCGAUCUUuu------------------------------------------------ 326 0,-3 ------------AACCCGUAGAUCCGAUCUUG------------------------------------------------- 6596 0,-2 ------------AACCCGUAGAUCCGAUCUUGa------------------------------------------------ 332 0,-2 ------------AACCCGUAGAUCCGAUCUUGaa----------------------------------------------- 6 0,-2 ------------AACCCGUAGAUCCGAUCUUGc------------------------------------------------ 177 0,-2 ------------AACCCGUAGAUCCGAUCUUGg------------------------------------------------ 122 0,-2 ------------AACCCGUAGAUCCGAUCUUGU------------------------------------------------ 81133 0,-1 ------------AACCCGUAGAUCCGAUCUUGUa----------------------------------------------- 744 0,-1 ------------AACCCGUAGAUCCGAUCUUGUaa---------------------------------------------- 187 0,-1 ------------AACCCGUAGAUCCGAUCUUGUau---------------------------------------------- 42 0,-1 ------------AACCCGUAGAUCCGAUCUUGUc----------------------------------------------- 34 0,-1 ------------AACCCGUAGAUCCGAUCUUGUu----------------------------------------------- 412 0,-1 ------------AACCCGUAGAUCCGAUCUUGUuu---------------------------------------------- 80 0,-1 ------------AACCCGUAGAUCCGAUCUUGUG----------------------------------------------- 53079 0,0 ------------AACCCGUAGAUCCGAUCUUGUGa---------------------------------------------- 32433 0,0 ------------AACCCGUAGAUCCGAUCUUGUGaa--------------------------------------------- 445 0,0 ------------AACCCGUAGAUCCGAUCUUGUGau--------------------------------------------- 53 0,0 ------------AACCCGUAGAUCCGAUCUUGUGc---------------------------------------------- 241 0,0 ------------AACCCGUAGAUCCGAUCUUGUGu---------------------------------------------- 24458 0,0 ------------AACCCGUAGAUCCGAUCUUGUGuu--------------------------------------------- 24 0,0 ------------AACCCGUAGAUCCGAUCUUGUGG---------------------------------------------- 339 0,1 ------------AACCCGUAGAUCCGAUCUUGUGGa--------------------------------------------- 4 0,1 ------------AACCCGUAGAUCCGAUCUUGUGGU--------------------------------------------- 4 0,2 -------------ACCCGUAGAUCCGAUCUU-------------------------------------------------- 22 1,-3 -------------ACCCGUAGAUCCGAUCUUG------------------------------------------------- 168 1,-2 -------------ACCCGUAGAUCCGAUCUUGc------------------------------------------------ 4 1,-2 -------------ACCCGUAGAUCCGAUCUUGU------------------------------------------------ 2655 1,-1 -------------ACCCGUAGAUCCGAUCUUGUa----------------------------------------------- 10 1,-1 -------------ACCCGUAGAUCCGAUCUUGUaa---------------------------------------------- 2 1,-1 -------------ACCCGUAGAUCCGAUCUUGUu----------------------------------------------- 10 1,-1 -------------ACCCGUAGAUCCGAUCUUGUuu---------------------------------------------- 2 1,-1 -------------ACCCGUAGAUCCGAUCUUGUG----------------------------------------------- 1837 1,0 -------------ACCCGUAGAUCCGAUCUUGUGa---------------------------------------------- 1254 1,0 -------------ACCCGUAGAUCCGAUCUUGUGaa--------------------------------------------- 2 1,0 -------------ACCCGUAGAUCCGAUCUUGUGc---------------------------------------------- 4 1,0 -------------ACCCGUAGAUCCGAUCUUGUGu---------------------------------------------- 764 1,0 -------------ACCCGUAGAUCCGAUCUUGUGG---------------------------------------------- 7 1,1 -------------ACCCGUAGAUCCGAUCUUGUGGa--------------------------------------------- 2 1,1 --------------CCCGUAGAUCCGAUCUUGUG----------------------------------------------- 4 2,0 -------------------------------------------------CAAGCUCGCUUCUAUGGGU------------- 30 0,-3 -------------------------------------------------CAAGCUCGCUUCUAUGGGUC------------ 23 0,-2 -------------------------------------------------CAAGCUCGCUUCUAUGGGUCa----------- 6 0,-2 -------------------------------------------------CAAGCUCGCUUCUAUGGGUCU----------- 257 0,-1 -------------------------------------------------CAAGCUCGCUUCUAUGGGUCUG---------- 110 0,0 -------------------------------------------------CAAGCUCGCUUCUAUGGGUCUGa--------- 168 0,0 -------------------------------------------------CAAGCUCGCUUCUAUGGGUCUGaa-------- 2 0,0 -------------------------------------------------CAAGCUCGCUUCUAUGGGUCUGU--------- 335 0,1 -------------------------------------------------CAAGCUCGCUUCUAUGGGUCUGUa-------- 4 0,1 -------------------------------------------------CAAGCUCGCUUCUAUGGGUCUGUu-------- 19 0,1 --------------------------------------------------AAGCUCGCUUCUAUGGGUCU----------- 7 1,-1 --------------------------------------------------AAGCUCGCUUCUAUGGGUCUGa--------- 6 1,0 --------------------------------------------------AAGCUCGCUUCUAUGGGUCUGU--------- 17 1,1 >hsa-mir-99b MA:7-28;mi:45-66 Tumor ggcaccCACCCGUAGAACCGACCUUGCGgggccuucgccgcacaCAAGCUCGUGUCUGUGGGUCCGuguc -----CCACCCGUAGAACCGACCUUGC------------------------------------------- 2 -1,-1 -----CCACCCGUAGAACCGACCUUGCG------------------------------------------ 14 -1,0 ------CACCCGUAGAACCGACCU---------------------------------------------- 79 0,-4 ------CACCCGUAGAACCGACCUU--------------------------------------------- 631 0,-3 ------CACCCGUAGAACCGACCUUu-------------------------------------------- 11 0,-3 ------CACCCGUAGAACCGACCUUG-------------------------------------------- 3746 0,-2 ------CACCCGUAGAACCGACCUUGa------------------------------------------- 191 0,-2 ------CACCCGUAGAACCGACCUUGu------------------------------------------- 176 0,-2 ------CACCCGUAGAACCGACCUUGC------------------------------------------- 12188 0,-1 ------CACCCGUAGAACCGACCUUGCa------------------------------------------ 313 0,-1 ------CACCCGUAGAACCGACCUUGCaa----------------------------------------- 15 0,-1 ------CACCCGUAGAACCGACCUUGCau----------------------------------------- 7 0,-1 ------CACCCGUAGAACCGACCUUGCc------------------------------------------ 15 0,-1 ------CACCCGUAGAACCGACCUUGCu------------------------------------------ 139 0,-1 ------CACCCGUAGAACCGACCUUGCG------------------------------------------ 34546 0,0 ------CACCCGUAGAACCGACCUUGCGa----------------------------------------- 5257 0,0 ------CACCCGUAGAACCGACCUUGCGaa---------------------------------------- 16 0,0 ------CACCCGUAGAACCGACCUUGCGau---------------------------------------- 20 0,0 ------CACCCGUAGAACCGACCUUGCGc----------------------------------------- 51 0,0 ------CACCCGUAGAACCGACCUUGCGu----------------------------------------- 3181 0,0 ------CACCCGUAGAACCGACCUUGCGuu---------------------------------------- 80 0,0 ------CACCCGUAGAACCGACCUUGCGG----------------------------------------- 15 0,1 -------ACCCGUAGAACCGACCUU--------------------------------------------- 9 1,-3 -------ACCCGUAGAACCGACCUUG-------------------------------------------- 127 1,-2 -------ACCCGUAGAACCGACCUUGa------------------------------------------- 4 1,-2 -------ACCCGUAGAACCGACCUUGC------------------------------------------- 579 1,-1 -------ACCCGUAGAACCGACCUUGCa------------------------------------------ 2 1,-1 -------ACCCGUAGAACCGACCUUGCu------------------------------------------ 2 1,-1 -------ACCCGUAGAACCGACCUUGCG------------------------------------------ 1751 1,0 -------ACCCGUAGAACCGACCUUGCGa----------------------------------------- 246 1,0 -------ACCCGUAGAACCGACCUUGCGu----------------------------------------- 135 1,0 --------CCCGUAGAACCGACCUUGCG------------------------------------------ 2 2,0 --------------------------------------------CAAGCUCGUGUCUGUGGG-------- 8 0,-4 --------------------------------------------CAAGCUCGUGUCUGUGGGa------- 2 0,-4 --------------------------------------------CAAGCUCGUGUCUGUGGGU------- 193 0,-3 --------------------------------------------CAAGCUCGUGUCUGUGGGUa------ 5 0,-3 --------------------------------------------CAAGCUCGUGUCUGUGGGUaa----- 2 0,-3 --------------------------------------------CAAGCUCGUGUCUGUGGGUau----- 2 0,-3 --------------------------------------------CAAGCUCGUGUCUGUGGGUC------ 179 0,-2 --------------------------------------------CAAGCUCGUGUCUGUGGGUCa----- 16 0,-2 --------------------------------------------CAAGCUCGUGUCUGUGGGUCau---- 2 0,-2 --------------------------------------------CAAGCUCGUGUCUGUGGGUCu----- 21 0,-2 --------------------------------------------CAAGCUCGUGUCUGUGGGUCuu---- 2 0,-2 --------------------------------------------CAAGCUCGUGUCUGUGGGUCC----- 121 0,-1 --------------------------------------------CAAGCUCGUGUCUGUGGGUCCu---- 5 0,-1 --------------------------------------------CAAGCUCGUGUCUGUGGGUCCG---- 252 0,0 --------------------------------------------CAAGCUCGUGUCUGUGGGUCCGa--- 354 0,0 --------------------------------------------CAAGCUCGUGUCUGUGGGUCCGaa-- 8 0,0 --------------------------------------------CAAGCUCGUGUCUGUGGGUCCGau-- 22 0,0 --------------------------------------------CAAGCUCGUGUCUGUGGGUCCGU--- 283 0,1 --------------------------------------------CAAGCUCGUGUCUGUGGGUCCGUu-- 115 0,1 --------------------------------------------CAAGCUCGUGUCUGUGGGUCCGUuu- 2 0,1 ---------------------------------------------AAGCUCGUGUCUGUGGGUC------ 2 1,-2 ---------------------------------------------AAGCUCGUGUCUGUGGGUCCG---- 5 1,0 ---------------------------------------------AAGCUCGUGUCUGUGGGUCCGa--- 4 1,0 ---------------------------------------------AAGCUCGUGUCUGUGGGUCCGU--- 8 1,1