Category Regulation -log(p-value) Ratio N Autoimmune Thyroid Disease Signaling Down 3.61 0.0328 3 B Cell Receptor Signaling Up 2.55 0.0182 2 CD28 Signaling in T Helper Cells Up 2.91 0.0227 2 Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells Down 3.46 0.0235 2 Death Receptor Signaling Down 1.51 0.0156 2 FAK Signaling Up 1.96 0.0198 2 Graft-versus-Host Disease Signaling Down 3.61 0.04 4 Granzyme B Signaling Down 2.07 0.0625 6 iCOS-iCOSL Signaling in T Helper Cells Up 3.02 0.0244 2 IL-17 Signaling Down 1.42 0.0135 1 MIF Regulation of Innate Immunity Down 1.69 0.02 2 MSP-RON Signaling Pathway Down 1.62 0.02 2 Myc Mediated Apoptosis Signaling Down 1.51 0.0167 2 Natural Killer Cell Signaling Up 2.99 0.0259 3 PI3K Signaling in B Lymphocytes Up 2.79 0.0214 2 Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes Up 2.02 0.0225 2 Role of IL-17A in Arthritis Down 1.54 0.0159 2 T Cell Receptor Signaling Up 1.85 0.0183 2 Tight Junction Signaling Up 2.62 0.0186 2 Tight Junction Signaling Up 2.62 0.0186 2 Tumoricidal Function of Hepatic Natural Killer Cells Down 4.16 0.0833 8