SigSet Set Sig All p_value q_value KEGG_path:mmu03320 13 69 213 15274 1.02e-11 1.37e-09 PPAR signaling pathway - Mus musculus (mouse) KEGG_path:mmu04920 12 73 213 15274 3.46e-10 1.66e-08 Adipocytokine signaling pathway - Mus musculus (mouse) KEGG_path:mmu04930 10 44 213 15274 3.69e-10 1.66e-08 Type II diabetes mellitus - Mus musculus (mouse) OdomYoung2004_ENSMUSG00000029556:TCF1_Liver 34 737 213 15274 6.85e-10 NA OdomYoung2006_ENSMUSG00000037025:FOXA2 33 738 213 15274 2.76e-09 NA OdomYoung2006_ENSMUSG00000017950:HNF4A 92 3812 213 15274 3.81e-09 NA KEGG_path:mmu04910 13 128 213 15274 2.7e-08 9.09e-07 Insulin signaling pathway - Mus musculus (mouse) OdomYoung2004_ENSMUSG00000017950:HNF4A_Liver 36 960 213 15274 4.79e-08 NA GO.cellular_component_GO:0005792 7 42 213 15274 1.66e-06 0.000574 microsome Reactome_Reactome:73923 6 31 213 15274 3.77e-06 0.00256 Lipid metabolism OdomYoung2006_ENSMUSG00000029556:TCF1 29 846 213 15274 6.66e-06 NA Reactome_Reactome:114611 6 35 213 15274 7.94e-06 0.0027 Exocytosis of Alpha granule GO.cellular_component_GO:0005739 17 350 213 15274 8.52e-06 0.00148 mitochondrion KEGG_path:mmu04612 6 38 213 15274 1.3e-05 0.000351 Antigen processing and presentation - Mus musculus (mouse) KEGG_path:mmu00280 6 44 213 15274 3.11e-05 0.000697 Valine, leucine and isoleucine degradation - Mus musculus (mouse) Reactome_Reactome:168249 6 45 213 15274 3.55e-05 0.00603 Innate Immunity Signaling Reactome_Reactome:168256 6 45 213 15274 3.55e-05 0.00603 Immune System signaling KEGG_path:mmu04610 7 67 213 15274 3.98e-05 0.000764 Complement and coagulation cascades - Mus musculus (mouse) KEGG_path:mmu00980 6 48 213 15274 5.16e-05 0.000867 Metabolism of xenobiotics by cytochrome P450 - Mus musculus (mouse) GO.biological_process_GO:0006094 3 6 213 15274 5.19e-05 0.102 gluconeogenesis GO.cellular_component_GO:0005783 7 70 213 15274 5.29e-05 0.00611 endoplasmic reticulum KEGG_path:mmu00590 6 51 213 15274 7.31e-05 0.00109 Arachidonic acid metabolism - Mus musculus (mouse) GO.cellular_component_GO:0005615 6 51 213 15274 7.31e-05 0.00633 extracellular space KEGG_path:mmu04620 7 77 213 15274 9.78e-05 0.00131 Toll-like receptor signaling pathway - Mus musculus (mouse) KEGG_path:mmu00480 5 35 213 15274 0.000116 0.00142 Glutathione metabolism - Mus musculus (mouse) Reactome_Reactome:166020 2 2 213 15274 0.000194 0.0144 LPS transferred from LBP carrier to CD14 Reactome_Reactome:173736 2 2 213 15274 0.000194 0.0144 Alternative complement activation Reactome_Reactome:75105 2 2 213 15274 0.000194 0.0144 Fatty Acyl-CoA Biosynthesis Reactome_Reactome:75107 2 2 213 15274 0.000194 0.0144 Butyryl-ACP biosynthesis Reactome_Reactome:75113 2 2 213 15274 0.000194 0.0144 Palmitate synthesis Reactome_Reactome:166663 3 9 213 15274 0.000211 0.0144 Initial triggering of complement TransFac_ENSMUSG00000034957:Cebpa 3 9 213 15274 0.000211 0.0395 KEGG_path:mmu00071 5 40 213 15274 0.000223 0.00249 Fatty acid metabolism - Mus musculus (mouse) KEGG_path:mmu00620 5 42 213 15274 0.000281 0.00291 Pyruvate metabolism - Mus musculus (mouse) OdomYoung2006_ENSMUSG00000043013:ONECUT1 30 1096 213 15274 0.000291 NA GO.molecular_function_GO:0019901 3 10 213 15274 0.000299 0.295 protein kinase binding KEGG_path:mmu00970 4 27 213 15274 0.000502 0.00482 Aminoacyl-tRNA biosynthesis - Mus musculus (mouse) Reactome_Reactome:174577 2 3 213 15274 0.000575 0.0356 Activation of C3 and C5 BioCyc_DETOX1-PWY 2 3 213 15274 0.000575 0.0844 removal of superoxide radicals GO.biological_process_GO:0006381 2 3 213 15274 0.000575 0.488 mRNA editing Reactome_Reactome:166658 3 15 213 15274 0.00107 0.0596 Complement cascade GO.cellular_component_GO:0005770 3 15 213 15274 0.00107 0.0594 late endosome GO.cellular_component_GO:0005743 8 148 213 15274 0.00111 0.0594 mitochondrial inner membrane Reactome_Reactome:163699 2 4 213 15274 0.00114 0.0596 Transcriptional activation of lipogenesis genes by ChREBP:MLX GO.biological_process_GO:0051085 2 4 213 15274 0.00114 0.488 chaperone cofactor-dependent protein folding GO.cellular_component_GO:0005829 7 116 213 15274 0.0012 0.0594 cytosol GO.biological_process_GO:0006629 3 16 213 15274 0.00131 0.488 lipid metabolism GO.biological_process_GO:0006916 4 36 213 15274 0.00153 0.488 anti-apoptosis GO.biological_process_GO:0006952 3 17 213 15274 0.00157 0.488 defense response Reactome_Reactome:75109 2 5 213 15274 0.00188 0.0914 Triacylglyceride Biosynthesis GO.molecular_function_GO:0005355 2 5 213 15274 0.00188 0.459 glucose transporter activity GO.molecular_function_GO:0004857 2 5 213 15274 0.00188 0.459 enzyme inhibitor activity GO.biological_process_GO:0008286 3 19 213 15274 0.0022 0.488 insulin receptor signaling pathway GO.biological_process_GO:0008283 4 40 213 15274 0.00227 0.488 cell proliferation OdomYoung2004_ENSMUSG00000043013:ONECUT1_PancreaticIslets 14 421 213 15274 0.00239 NA GO.cellular_component_GO:0005768 3 20 213 15274 0.00256 0.111 endosome GO.molecular_function_GO:0005041 2 6 213 15274 0.0028 0.459 low-density lipoprotein receptor activity GO.biological_process_GO:0042632 2 6 213 15274 0.0028 0.488 cholesterol homeostasis GO.biological_process_GO:0001889 2 6 213 15274 0.0028 0.488 liver development KEGG_path:mmu05212 5 70 213 15274 0.00292 0.0255 Pancreatic cancer - Mus musculus (mouse) OdomYoung2004_ENSMUSG00000043013:ONECUT1_Liver 18 627 213 15274 0.00304 NA GO.cellular_component_GO:0005634 20 730 213 15274 0.00309 0.119 nucleus KEGG_path:mmu00561 4 44 213 15274 0.00323 0.0255 Glycerolipid metabolism - Mus musculus (mouse) KEGG_path:mmu04150 4 44 213 15274 0.00323 0.0255 mTOR signaling pathway - Mus musculus (mouse) KEGG_path:mmu00903 3 23 213 15274 0.00385 0.0266 Limonene and pinene degradation - Mus musculus (mouse) KEGG_path:mmu04950 3 23 213 15274 0.00385 0.0266 Maturity onset diabetes of the young - Mus musculus (mouse) KEGG_path:mmu00330 4 47 213 15274 0.0041 0.0266 Arginine and proline metabolism - Mus musculus (mouse) KEGG_path:mmu00030 3 24 213 15274 0.00436 0.0266 Pentose phosphate pathway - Mus musculus (mouse) KEGG_path:mmu00860 3 24 213 15274 0.00436 0.0266 Porphyrin and chlorophyll metabolism - Mus musculus (mouse) GO.cellular_component_GO:0005578 4 48 213 15274 0.00443 0.153 extracellular matrix (sensu Metazoa) KEGG_path:mmu00020 3 25 213 15274 0.0049 0.0287 Citrate cycle (TCA cycle) - Mus musculus (mouse) GO.biological_process_GO:0043524 2 8 213 15274 0.00513 0.488 negative regulation of neuron apoptosis KEGG_path:mmu00010 4 50 213 15274 0.00513 0.0287 Glycolysis / Gluconeogenesis - Mus musculus (mouse) KEGG_path:mmu00632 3 27 213 15274 0.00611 0.0329 Benzoate degradation via CoA ligation - Mus musculus (mouse) Reactome_Reactome:109582 4 53 213 15274 0.00631 0.286 Hemostasis GO.biological_process_GO:0048514 2 9 213 15274 0.00653 0.488 blood vessel morphogenesis TransFac_ENSMUSG00000025958:Creb1 2 9 213 15274 0.00653 0.373 BioCyc_TRNA-CHARGING-PWY 3 29 213 15274 0.00748 0.179 tRNA charging pathway GO.biological_process_GO:0019886 2 10 213 15274 0.00809 0.488 antigen processing, exogenous antigen via MHC class II GO.biological_process_GO:0007595 2 10 213 15274 0.00809 0.488 lactation Reactome_Reactome:168898 3 30 213 15274 0.00823 0.316 Toll Receptor Cascades KEGG_path:mmu00564 4 58 213 15274 0.00867 0.0448 Glycerophospholipid metabolism - Mus musculus (mouse) KEGG_path:mmu00040 2 11 213 15274 0.0098 0.0471 Pentose and glucuronate interconversions - Mus musculus (mouse) KEGG_path:mmu00720 2 11 213 15274 0.0098 0.0471 Reductive carboxylate cycle (CO2 fixation) - Mus musculus (mouse) Reactome_Reactome:174800 2 11 213 15274 0.0098 0.316 Chylomicron-mediated lipid transport Reactome_Reactome:174824 2 11 213 15274 0.0098 0.316 Lipoprotein metabolism BioCyc_NPGLUCAT-PWY 2 11 213 15274 0.0098 0.179 Entner-Doudoroff pathway II (non-phosphorylative) BioCyc_PHENYLALANINE-DEG1-PWY 2 11 213 15274 0.0098 0.179 phenylalanine degradation I GO.biological_process_GO:0050766 2 11 213 15274 0.0098 0.488 positive regulation of phagocytosis GO.biological_process_GO:0045444 2 11 213 15274 0.0098 0.488 fat cell differentiation GO.biological_process_GO:0006508 2 11 213 15274 0.0098 0.488 proteolysis Reactome_Reactome:73847 3 33 213 15274 0.0107 0.316 Purine metabolism KEGG_path:mmu04510 7 175 213 15274 0.0115 0.0532 Focal adhesion - Mus musculus (mouse) GO.biological_process_GO:0007420 3 34 213 15274 0.0116 0.488 brain development BioCyc_VALDEG-PWY 2 12 213 15274 0.0117 0.179 valine degradation I BioCyc_ILEUDEG-PWY 2 12 213 15274 0.0117 0.179 isoleucine degradation I KEGG_path:mmu00591 3 35 213 15274 0.0126 0.0565 Linoleic acid metabolism - Mus musculus (mouse) KEGG_path:mmu00642 2 13 213 15274 0.0136 0.0592 Ethylbenzene degradation - Mus musculus (mouse) Reactome_Reactome:166016 2 13 213 15274 0.0136 0.316 Toll Like Receptor 4 (TLR4) Cascade Reactome_Reactome:110619 1 1 213 15274 0.0139 0.316 Reversible phosphorylation of cytosolic nucleoside diphosphates by nucleoside diphosphate kinase B hexamer Reactome_Reactome:110658 1 1 213 15274 0.0139 0.316 Reversible phosphorylation of cytosolic nucleoside diphosphates by nucleoside diphosphate kinase A,B heterohexamer Reactome_Reactome:75852 1 1 213 15274 0.0139 0.316 Formation of Malonyl-ACP on the other FAS monomer Reactome_Reactome:75854 1 1 213 15274 0.0139 0.316 Formation of Acetyl-FAS on one FAS monomer Reactome_Reactome:72200 1 1 213 15274 0.0139 0.316 mRNA Editing: C to U Conversion Reactome_Reactome:75094 1 1 213 15274 0.0139 0.316 Formation of the Editosome Reactome_Reactome:71288 1 1 213 15274 0.0139 0.316 Creatine metabolism Reactome_Reactome:71336 1 1 213 15274 0.0139 0.316 Pentose phosphate pathway (hexose monophosphate shunt) Reactome_Reactome:163754 1 1 213 15274 0.0139 0.316 Insulin effects increased synthesis of Xylulose-5-Phosphate Reactome_Reactome:110579 1 1 213 15274 0.0139 0.316 Reversible phosphorylation of cytosolic nucleoside diphosphates by nucleoside diphosphate kinase A hexamer BioCyc_PWY66-221 1 1 213 15274 0.0139 0.179 nicotine degradation III BioCyc_PWY0-846 1 1 213 15274 0.0139 0.179 superpathway of saturated and unsaturated fatty acid elongation BioCyc_FASYN-ELONG-PWY 1 1 213 15274 0.0139 0.179 fatty acid elongation -- saturated BioCyc_PUTDEG-PWY 1 1 213 15274 0.0139 0.179 putrescine degradation BioCyc_UNSAT-FA-ELONG-PWY 1 1 213 15274 0.0139 0.179 fatty acid elongation -- unsaturated GO.molecular_function_GO:0004031 1 1 213 15274 0.0139 0.459 aldehyde oxidase activity GO.molecular_function_GO:0016620 1 1 213 15274 0.0139 0.459 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO.molecular_function_GO:0003845 1 1 213 15274 0.0139 0.459 11-beta-hydroxysteroid dehydrogenase activity GO.molecular_function_GO:0004096 1 1 213 15274 0.0139 0.459 catalase activity GO.molecular_function_GO:0016684 1 1 213 15274 0.0139 0.459 oxidoreductase activity, acting on peroxide as acceptor GO.molecular_function_GO:0001530 1 1 213 15274 0.0139 0.459 lipopolysaccharide binding GO.molecular_function_GO:0004611 1 1 213 15274 0.0139 0.459 phosphoenolpyruvate carboxykinase activity GO.molecular_function_GO:0004218 1 1 213 15274 0.0139 0.459 cathepsin S activity GO.molecular_function_GO:0042171 1 1 213 15274 0.0139 0.459 lysophosphatidic acid acyltransferase activity GO.molecular_function_GO:0005388 1 1 213 15274 0.0139 0.459 calcium-transporting ATPase activity GO.molecular_function_GO:0004566 1 1 213 15274 0.0139 0.459 beta-glucuronidase activity GO.molecular_function_GO:0001735 1 1 213 15274 0.0139 0.459 prenylcysteine oxidase activity GO.molecular_function_GO:0004347 1 1 213 15274 0.0139 0.459 glucose-6-phosphate isomerase activity GO.molecular_function_GO:0031699 1 1 213 15274 0.0139 0.459 beta-3 adrenergic receptor binding GO.molecular_function_GO:0008379 1 1 213 15274 0.0139 0.459 thioredoxin peroxidase activity GO.molecular_function_GO:0031702 1 1 213 15274 0.0139 0.459 type 1 angiotensin receptor binding GO.molecular_function_GO:0003826 1 1 213 15274 0.0139 0.459 alpha-ketoacid dehydrogenase activity GO.molecular_function_GO:0005360 1 1 213 15274 0.0139 0.459 insulin-responsive hydrogen:glucose transporter activity GO.molecular_function_GO:0003878 1 1 213 15274 0.0139 0.459 ATP citrate synthase activity GO.molecular_function_GO:0001509 1 1 213 15274 0.0139 0.459 legumain activity GO.molecular_function_GO:0008234 1 1 213 15274 0.0139 0.459 cysteine-type peptidase activity GO.molecular_function_GO:0004802 1 1 213 15274 0.0139 0.459 transketolase activity GO.molecular_function_GO:0016831 1 1 213 15274 0.0139 0.459 carboxy-lyase activity GO.molecular_function_GO:0008383 1 1 213 15274 0.0139 0.459 manganese superoxide dismutase activity GO.molecular_function_GO:0004854 1 1 213 15274 0.0139 0.459 xanthine dehydrogenase activity GO.molecular_function_GO:0005158 1 1 213 15274 0.0139 0.459 insulin receptor binding GO.biological_process_GO:0009437 1 1 213 15274 0.0139 0.488 carnitine metabolism GO.biological_process_GO:0001811 1 1 213 15274 0.0139 0.488 negative regulation of type I hypersensitivity GO.biological_process_GO:0045408 1 1 213 15274 0.0139 0.488 regulation of interleukin-6 biosynthesis GO.biological_process_GO:0046327 1 1 213 15274 0.0139 0.488 glycerol biosynthesis from pyruvate GO.biological_process_GO:0006654 1 1 213 15274 0.0139 0.488 phosphatidic acid biosynthesis GO.biological_process_GO:0006984 1 1 213 15274 0.0139 0.488 ER-nuclear signaling pathway GO.biological_process_GO:0045055 1 1 213 15274 0.0139 0.488 regulated secretory pathway GO.biological_process_GO:0030328 1 1 213 15274 0.0139 0.488 prenylcysteine catabolism GO.biological_process_GO:0042157 1 1 213 15274 0.0139 0.488 lipoprotein metabolism GO.biological_process_GO:0009956 1 1 213 15274 0.0139 0.488 radial pattern formation GO.biological_process_GO:0002025 1 1 213 15274 0.0139 0.488 norepinephrine-epinephrine vasodilation during regulation of blood pressure GO.biological_process_GO:0008065 1 1 213 15274 0.0139 0.488 establishment of blood-nerve barrier GO.biological_process_GO:0045723 1 1 213 15274 0.0139 0.488 positive regulation of fatty acid biosynthesis GO.biological_process_GO:0046622 1 1 213 15274 0.0139 0.488 positive regulation of organ size GO.biological_process_GO:0048143 1 1 213 15274 0.0139 0.488 astrocyte activation GO.biological_process_GO:0048659 1 1 213 15274 0.0139 0.488 smooth muscle cell proliferation GO.biological_process_GO:0001999 1 1 213 15274 0.0139 0.488 renal response to blood flow during renin-angiotensin regulation of blood pressure GO.biological_process_GO:0001998 1 1 213 15274 0.0139 0.488 angiotensin mediated vasoconstriction during regulation of blood pressure GO.biological_process_GO:0035264 1 1 213 15274 0.0139 0.488 body growth GO.biological_process_GO:0006590 1 1 213 15274 0.0139 0.488 thyroid hormone generation GO.biological_process_GO:0045746 1 1 213 15274 0.0139 0.488 negative regulation of Notch signaling pathway GO.biological_process_GO:0019858 1 1 213 15274 0.0139 0.488 cytosine metabolism GO.biological_process_GO:0009749 1 1 213 15274 0.0139 0.488 response to glucose stimulus GO.biological_process_GO:0045721 1 1 213 15274 0.0139 0.488 negative regulation of gluconeogenesis GO.biological_process_GO:0045923 1 1 213 15274 0.0139 0.488 positive regulation of fatty acid metabolism GO.biological_process_GO:0009967 1 1 213 15274 0.0139 0.488 positive regulation of signal transduction GO.biological_process_GO:0051005 1 1 213 15274 0.0139 0.488 negative regulation of lipoprotein lipase activity GO.biological_process_GO:0006957 1 1 213 15274 0.0139 0.488 complement activation, alternative pathway GO.biological_process_GO:0045581 1 1 213 15274 0.0139 0.488 negative regulation of T cell differentiation GO.biological_process_GO:0042177 1 1 213 15274 0.0139 0.488 negative regulation of protein catabolism GO.biological_process_GO:0050482 1 1 213 15274 0.0139 0.488 arachidonic acid secretion GO.biological_process_GO:0006178 1 1 213 15274 0.0139 0.488 guanine salvage GO.biological_process_GO:0021756 1 1 213 15274 0.0139 0.488 striatum development GO.biological_process_GO:0021895 1 1 213 15274 0.0139 0.488 cerebral cortex neuron differentiation GO.biological_process_GO:0021954 1 1 213 15274 0.0139 0.488 central nervous system neuron development GO.biological_process_GO:0045964 1 1 213 15274 0.0139 0.488 positive regulation of dopamine metabolism GO.biological_process_GO:0046100 1 1 213 15274 0.0139 0.488 hypoxanthine metabolism GO.biological_process_GO:0048813 1 1 213 15274 0.0139 0.488 dendrite morphogenesis GO.cellular_component_GO:0005942 1 1 213 15274 0.0139 0.345 phosphoinositide 3-kinase complex GO.cellular_component_GO:0005575 1 1 213 15274 0.0139 0.345 cellular_component GO.cellular_component_GO:0042175 1 1 213 15274 0.0139 0.345 nuclear envelope-endoplasmic reticulum network GO.cellular_component_GO:0005924 1 1 213 15274 0.0139 0.345 cell-substrate adherens junction TransFac_ENSMUSG00000002428:Smarca3 1 1 213 15274 0.0139 0.373 TransFac_ENSMUSG00000020538:Srebf1 1 1 213 15274 0.0139 0.373 TransFac_ENSMUSG00000030189:Csda 1 1 213 15274 0.0139 0.373 TransFac_ENSMUSG00000060601:Nr1h2 1 1 213 15274 0.0139 0.373 TransFac_ENSMUSG00000062421:Arf2 1 1 213 15274 0.0139 0.373 KEGG_path:mmu04370 4 67 213 15274 0.0142 0.0597 VEGF signaling pathway - Mus musculus (mouse) BioCyc_PWY1G-2 3 37 213 15274 0.0147 0.179 superpathway of glycolysis and TCA variant VIII KEGG_path:mmu04520 4 69 213 15274 0.0157 0.0623 Adherens junction - Mus musculus (mouse) KEGG_path:mmu00760 3 38 213 15274 0.0158 0.0623 Nicotinate and nicotinamide metabolism - Mus musculus (mouse) Reactome_Reactome:168180 2 14 213 15274 0.0158 0.346 TRAF6 Mediated Induction of the antiviral cytokine IFN-alpha beta cascade Reactome_Reactome:140837 2 15 213 15274 0.018 0.383 Intrinsic Pathway GO.biological_process_GO:0006979 2 15 213 15274 0.018 0.599 response to oxidative stress GO.biological_process_GO:0016064 2 15 213 15274 0.018 0.599 humoral defense mechanism (sensu Vertebrata) GO.biological_process_GO:0006006 2 15 213 15274 0.018 0.599 glucose metabolism KEGG_path:mmu04664 4 73 213 15274 0.0189 0.0702 Fc epsilon RI signaling pathway - Mus musculus (mouse) KEGG_path:mmu05220 4 73 213 15274 0.0189 0.0702 Chronic myeloid leukemia - Mus musculus (mouse) KEGG_path:mmu00260 3 41 213 15274 0.0193 0.0702 Glycine, serine and threonine metabolism - Mus musculus (mouse) GO.molecular_function_GO:0004672 3 41 213 15274 0.0193 0.615 protein kinase activity GO.biological_process_GO:0015758 2 16 213 15274 0.0204 0.603 glucose transport OdomYoung2004_ENSMUSG00000017950:HNF4A_PancreaticIslets 22 991 213 15274 0.0208 NA GO.cellular_component_GO:0016020 3 44 213 15274 0.0233 0.533 membrane GO.biological_process_GO:0006468 4 79 213 15274 0.0245 0.603 protein amino acid phosphorylation GO.molecular_function_GO:0003677 8 253 213 15274 0.0258 0.683 DNA binding Reactome_Reactome:70102 1 2 213 15274 0.0277 0.509 Phosphoenolpyruvate and ADP react to form pyruvate and ATP Reactome_Reactome:112411 1 2 213 15274 0.0277 0.509 ERK2 activation Reactome_Reactome:111446 1 2 213 15274 0.0277 0.509 Activation of BIM and translocation to mitochondria Reactome_Reactome:171052 1 2 213 15274 0.0277 0.509 LDL endocytosis Reactome_Reactome:77285 1 2 213 15274 0.0277 0.509 Beta oxidation of myristoyl-CoA to lauroyl-CoA BioCyc_NADPHOS-DEPHOS-PWY 1 2 213 15274 0.0277 0.226 NAD phosphorylation and dephosphorylation BioCyc_PWY66-161 1 2 213 15274 0.0277 0.226 oxidative ethanol degradation II BioCyc_PWY66-162 1 2 213 15274 0.0277 0.226 oxidative ethanol degradation III BioCyc_GLYCGREAT-PWY 1 2 213 15274 0.0277 0.226 glycine degradation II BioCyc_BETSYN-PWY 1 2 213 15274 0.0277 0.226 betaine biosynthesis I BioCyc_CYSDEGRV-PWY 1 2 213 15274 0.0277 0.226 L-cysteine degradation VI GO.molecular_function_GO:0043022 1 2 213 15274 0.0277 0.683 ribosome binding GO.molecular_function_GO:0004667 1 2 213 15274 0.0277 0.683 prostaglandin-D synthase activity GO.molecular_function_GO:0005504 1 2 213 15274 0.0277 0.683 fatty acid binding GO.molecular_function_GO:0004345 1 2 213 15274 0.0277 0.683 glucose-6-phosphate 1-dehydrogenase activity GO.molecular_function_GO:0004712 1 2 213 15274 0.0277 0.683 protein threonine/tyrosine kinase activity GO.molecular_function_GO:0004707 1 2 213 15274 0.0277 0.683 MAP kinase activity GO.molecular_function_GO:0004656 1 2 213 15274 0.0277 0.683 procollagen-proline 4-dioxygenase activity GO.molecular_function_GO:0004422 1 2 213 15274 0.0277 0.683 hypoxanthine phosphoribosyltransferase activity GO.biological_process_GO:0050777 1 2 213 15274 0.0277 0.603 negative regulation of immune response GO.biological_process_GO:0006072 1 2 213 15274 0.0277 0.603 glycerol-3-phosphate metabolism GO.biological_process_GO:0045666 1 2 213 15274 0.0277 0.603 positive regulation of neuron differentiation GO.biological_process_GO:0008643 1 2 213 15274 0.0277 0.603 carbohydrate transport GO.biological_process_GO:0051084 1 2 213 15274 0.0277 0.603 posttranslational protein folding GO.biological_process_GO:0001844 1 2 213 15274 0.0277 0.603 protein insertion into mitochondrial membrane during induction of apoptosis GO.biological_process_GO:0008654 1 2 213 15274 0.0277 0.603 phospholipid biosynthesis GO.biological_process_GO:0050779 1 2 213 15274 0.0277 0.603 RNA destabilization GO.biological_process_GO:0001781 1 2 213 15274 0.0277 0.603 neutrophil apoptosis GO.biological_process_GO:0045079 1 2 213 15274 0.0277 0.603 negative regulation of chemokine biosynthesis GO.biological_process_GO:0006086 1 2 213 15274 0.0277 0.603 acetyl-CoA biosynthesis from pyruvate GO.biological_process_GO:0048009 1 2 213 15274 0.0277 0.603 insulin-like growth factor receptor signaling pathway GO.biological_process_GO:0016554 1 2 213 15274 0.0277 0.603 cytidine to uridine editing GO.biological_process_GO:0045087 1 2 213 15274 0.0277 0.603 innate immune response GO.biological_process_GO:0007263 1 2 213 15274 0.0277 0.603 nitric oxide mediated signal transduction GO.biological_process_GO:0006168 1 2 213 15274 0.0277 0.603 adenine salvage GO.biological_process_GO:0030432 1 2 213 15274 0.0277 0.603 peristalsis GO.biological_process_GO:0001543 1 2 213 15274 0.0277 0.603 ovarian follicle rupture GO.biological_process_GO:0002018 1 2 213 15274 0.0277 0.603 renin-angiotensin regulation of aldosterone production GO.biological_process_GO:0002019 1 2 213 15274 0.0277 0.603 angiotensin mediated regulation of renal output GO.biological_process_GO:0001991 1 2 213 15274 0.0277 0.603 regulation of blood pressure by circulatory renin-angiotensin GO.biological_process_GO:0007527 1 2 213 15274 0.0277 0.603 adult somatic muscle development GO.biological_process_GO:0018401 1 2 213 15274 0.0277 0.603 peptidyl-proline hydroxylation to 4-hydroxy-L-proline GO.biological_process_GO:0046326 1 2 213 15274 0.0277 0.603 positive regulation of glucose import GO.biological_process_GO:0006166 1 2 213 15274 0.0277 0.603 purine ribonucleoside salvage GO.biological_process_GO:0006869 1 2 213 15274 0.0277 0.603 lipid transport GO.biological_process_GO:0019452 1 2 213 15274 0.0277 0.603 L-cysteine catabolism to taurine GO.biological_process_GO:0019530 1 2 213 15274 0.0277 0.603 taurine metabolism GO.biological_process_GO:0006461 1 2 213 15274 0.0277 0.603 protein complex assembly GO.cellular_component_GO:0009331 1 2 213 15274 0.0277 0.533 glycerol-3-phosphate dehydrogenase complex GO.cellular_component_GO:0005815 1 2 213 15274 0.0277 0.533 microtubule organizing center GO.cellular_component_GO:0042587 1 2 213 15274 0.0277 0.533 glycogen granule TransFac_ENSMUSG00000044167:Foxo1 1 2 213 15274 0.0277 0.575 TransFac_ENSMUSG00000048047:Zbtb33 1 2 213 15274 0.0277 0.575 GO.biological_process_GO:0030198 2 19 213 15274 0.0283 0.61 extracellular matrix organization and biogenesis KEGG_path:mmu00500 3 49 213 15274 0.0308 0.108 Starch and sucrose metabolism - Mus musculus (mouse) KEGG_path:mmu00710 2 20 213 15274 0.0312 0.108 Carbon fixation - Mus musculus (mouse) BioCyc_P105-PWY 2 20 213 15274 0.0312 0.241 TCA cycle variation VIII GO.biological_process_GO:0001568 2 20 213 15274 0.0312 0.664 blood vessel development KEGG_path:mmu00624 2 21 213 15274 0.0342 0.115 1- and 2-Methylnaphthalene degradation - Mus musculus (mouse) BioCyc_PWY-561 2 21 213 15274 0.0342 0.25 glyoxylate cycle II GO.biological_process_GO:0006974 2 21 213 15274 0.0342 0.697 response to DNA damage stimulus KEGG_path:mmu04912 4 90 213 15274 0.0371 0.122 GnRH signaling pathway - Mus musculus (mouse) GO.biological_process_GO:0009887 4 90 213 15274 0.0371 0.697 organ morphogenesis Reactome_Reactome:15869 3 53 213 15274 0.0376 0.652 Nucleotide metabolism KEGG_path:mmu00791 1 3 213 15274 0.0413 0.131 Atrazine degradation - Mus musculus (mouse) Reactome_Reactome:74219 1 3 213 15274 0.0413 0.652 dGTP formation Reactome_Reactome:74230 1 3 213 15274 0.0413 0.652 dATP formation Reactome_Reactome:75072 1 3 213 15274 0.0413 0.652 mRNA Editing Reactome_Reactome:163560 1 3 213 15274 0.0413 0.652 Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Reactome_Reactome:110580 1 3 213 15274 0.0413 0.652 Reversible phosphorylation of nucleoside diphosphates BioCyc_ARGDEG-PWY 1 3 213 15274 0.0413 0.263 superpathway of arginine, putrescine, and 4-aminobutyrate degradation BioCyc_ARGDEG-III-PWY 1 3 213 15274 0.0413 0.263 arginine degradation III BioCyc_PWY66-201 1 3 213 15274 0.0413 0.263 nicotine degradation II GO.molecular_function_GO:0004867 1 3 213 15274 0.0413 0.925 serine-type endopeptidase inhibitor activity GO.molecular_function_GO:0004601 1 3 213 15274 0.0413 0.925 peroxidase activity GO.molecular_function_GO:0001784 1 3 213 15274 0.0413 0.925 phosphotyrosine binding GO.molecular_function_GO:0004623 1 3 213 15274 0.0413 0.925 phospholipase A2 activity GO.biological_process_GO:0009409 1 3 213 15274 0.0413 0.697 response to cold GO.biological_process_GO:0001667 1 3 213 15274 0.0413 0.697 ameboidal cell migration GO.biological_process_GO:0043410 1 3 213 15274 0.0413 0.697 positive regulation of MAPKKK cascade GO.biological_process_GO:0016574 1 3 213 15274 0.0413 0.697 histone ubiquitination GO.biological_process_GO:0001975 1 3 213 15274 0.0413 0.697 response to amphetamine GO.biological_process_GO:0006693 1 3 213 15274 0.0413 0.697 prostaglandin metabolism GO.biological_process_GO:0006085 1 3 213 15274 0.0413 0.697 acetyl-CoA biosynthesis GO.biological_process_GO:0050729 1 3 213 15274 0.0413 0.697 positive regulation of inflammatory response GO.biological_process_GO:0048637 1 3 213 15274 0.0413 0.697 skeletal muscle development GO.biological_process_GO:0045672 1 3 213 15274 0.0413 0.697 positive regulation of osteoclast differentiation GO.biological_process_GO:0016042 1 3 213 15274 0.0413 0.697 lipid catabolism GO.biological_process_GO:0042574 1 3 213 15274 0.0413 0.697 retinal metabolism GO.biological_process_GO:0016310 1 3 213 15274 0.0413 0.697 phosphorylation GO.biological_process_GO:0043149 1 3 213 15274 0.0413 0.697 stress fiber formation GO.biological_process_GO:0046651 1 3 213 15274 0.0413 0.697 lymphocyte proliferation GO.biological_process_GO:0045598 1 3 213 15274 0.0413 0.697 regulation of fat cell differentiation GO.biological_process_GO:0045638 1 3 213 15274 0.0413 0.697 negative regulation of myeloid cell differentiation GO.biological_process_GO:0042692 1 3 213 15274 0.0413 0.697 muscle cell differentiation GO.biological_process_GO:0002035 1 3 213 15274 0.0413 0.697 brain renin-angiotensin system GO.biological_process_GO:0006325 1 3 213 15274 0.0413 0.697 establishment and/or maintenance of chromatin architecture GO.biological_process_GO:0019835 1 3 213 15274 0.0413 0.697 cytolysis GO.biological_process_GO:0019395 1 3 213 15274 0.0413 0.697 fatty acid oxidation GO.cellular_component_GO:0000922 1 3 213 15274 0.0413 0.714 spindle pole GO.cellular_component_GO:0030659 1 3 213 15274 0.0413 0.714 cytoplasmic vesicle membrane TransFac_ENSMUSG00000022528:Hes1 1 3 213 15274 0.0413 0.701 TransFac_ENSMUSG00000029644:Ipf1 1 3 213 15274 0.0413 0.701 KEGG_path:mmu00230 5 136 213 15274 0.0419 0.131 Purine metabolism - Mus musculus (mouse) KEGG_path:mmu04810 6 186 213 15274 0.0463 0.141 Regulation of actin cytoskeleton - Mus musculus (mouse) KEGG_path:mmu00361 2 25 213 15274 0.0471 0.141 gamma-Hexachlorocyclohexane degradation - Mus musculus (mouse) Reactome_Reactome:71408 2 25 213 15274 0.0471 0.711 Metabolism of small molecules Reactome_Reactome:71387 2 25 213 15274 0.0471 0.711 Carbohydrate metabolism GO.cellular_component_GO:0005604 2 25 213 15274 0.0471 0.728 basement membrane