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[]
[null,null,"Q-valuea"]
["Gene set",null,"4h/3hb",null,null,"4.6h/3h",null,null,"5h/3h",null,null,"5.5h/3h",null,null,"6h/3h"]
["Amino acid biosynthesis"]
[null,"Aromatic amino acid family",null,{"v":0.14130825,"d":"0.1413"},"(-)",{"$nulls":10},{"v":0.019323492,"d":"0.0193"},"(-)"]
[null,"Aspartate family",{"$nulls":7},{"v":0,"d":"0.0000"},"(-)",null,{"v":0,"d":"0.0000"},"(-)",null,{"v":0,"d":"0.0000"},"(-)"]
[null,"Glutamate family",{"$nulls":4},{"v":0.031362955,"d":"0.0314"},"(+)",null,{"v":0.007085791,"d":"0.0071"},"(-)",null,{"v":0.00023333334,"d":"0.0002"},"(-)",null,{"v":0.0006427887,"d":"0.0006"},"(-)"]
[null,"Histidine family",{"$nulls":7},{"v":0.030681172,"d":"0.0307"},"(-)",null,{"v":0.007171722,"d":"0.0072"},"(-)",null,{"v":0.00021960784,"d":"0.0002"},"(-)"]
[null,"Serine family",{"$nulls":7},{"v":0.050997455,"d":"0.0510"},"(-)",null,{"v":0.09082132,"d":"0.0908"},"(-)",null,{"v":0.067706764,"d":"0.0677"},"(-)"]
["Biosynthesis of cofactors, prosthetic groups, and carriers"]
[null,"Biotin",{"$nulls":7},{"v":0.05009398,"d":"0.0501"},"(-)",null,{"v":0.004383395,"d":"0.0044"},"(-)",null,{"v":0.005322602,"d":"0.0053"},"(-)"]
[null,"Folic acid",{"$nulls":7},{"v":0.038438708,"d":"0.0384"},"(-)",null,{"v":0.0739234,"d":"0.0739"},"(-)",null,{"v":0.015587811,"d":"0.0156"},"(-)"]
[null,"Molybdopterin",null,{"v":0.20784596,"d":"0.2078"},"(+)"]
[null,"Pantothenate and coenzyme A",{"$nulls":10},{"v":0.115593545,"d":"0.1156"},"(-)",null,{"v":0.06943217,"d":"0.0694"},"(-)"]
[null,"Pyridoxine",{"$nulls":7},{"v":0.14877807,"d":"0.1488"},"(-)",null,{"v":0.05478783,"d":"0.0548"},"(-)",null,{"v":0.0462932,"d":"0.0463"},"(-)"]
[null,"Riboflavin, FMN, and FAD",{"$nulls":10},{"v":0.20932393,"d":"0.2093"},"(-)"]
[null,"Thiamine",{"$nulls":7},{"v":0.030212486,"d":"0.0302"},"(-)",null,{"v":0.07691551,"d":"0.0769"},"(-)",null,{"v":0.05496459,"d":"0.0550"},"(-)"]
["Cell envelope"]
[null,"Biosynthesis and degradation of murein sacculus and peptidoglycan",{"$nulls":7},{"v":0.075314015,"d":"0.0753"},"(-)",null,{"v":0.026906893,"d":"0.0269"},"(-)",null,{"v":0.04142158,"d":"0.0414"},"(-)"]
[null,"Other",{"$nulls":7},{"v":0.00529801,"d":"0.0053"},"(-)",null,{"v":0.0052157743,"d":"0.0052"},"(-)",null,{"v":0.03958215,"d":"0.0396"},"(-)"]
["Cellular processes"]
[null,"acid resistance fitness island",null,{"v":0.06427288,"d":"0.0643"},"(+)",null,{"v":0,"d":"0.0000"},"(+)",null,{"v":0.00026811598,"d":"0.0003"},"(+)",null,{"v":0,"d":"0.0000"},"(+)",null,{"v":0,"d":"0.0000"},"(+)"]
[null,"Adaptations to atypical conditions",{"$nulls":4},{"v":0.22344889,"d":"0.2234"},"(+)",null,{"v":0.00020108696,"d":"0.0002"},"(+)",null,{"v":0.01596133,"d":"0.0160"},"(+)",null,{"v":0.0062059807,"d":"0.0062"},"(+)"]
[null,"Other",{"$nulls":10},{"v":0.0025257426,"d":"0.0025"},"(+)",null,{"v":0.006613424,"d":"0.0066"},"(+)"]
[null,"Pathogenesis",{"$nulls":13},{"v":0.22053297,"d":"0.2205"},"(+)"]
[null,"type III secretion system",{"$nulls":7},{"v":0.0032189195,"d":"0.0032"},"(-)",null,{"v":0.0029939753,"d":"0.0030"},"(-)",null,{"v":0.0015561169,"d":"0.0016"},"(-)"]
["Central intermediary metabolism"]
[null,"Nitrogen metabolism",{"$nulls":7},{"v":0.10162067,"d":"0.1016"},"(-)"]
[null,"Other",{"$nulls":4},{"v":0.22436889,"d":"0.2244"},"(+)"]
[null,"Phosphorus compounds",{"$nulls":7},{"v":0.2209879,"d":"0.2210"},"(+)",null,{"v":0.043108046,"d":"0.0431"},"(+)",null,{"v":0.062254217,"d":"0.0623"},"(+)"]
[null,"Polyamine biosynthesis",{"$nulls":4},{"v":0.1547501,"d":"0.1548"},"(-)",null,{"v":0.043615412,"d":"0.0436"},"(-)",null,{"v":0.11785521,"d":"0.1179"},"(-)",null,{"v":0.11484604,"d":"0.1148"},"(-)"]
[null,"Sulfur metabolism",{"$nulls":4},{"v":0.15304254,"d":"0.1530"},"(-)",null,{"v":0.051505663,"d":"0.0515"},"(-)",null,{"v":0.14387517,"d":"0.1439"},"(-)",null,{"v":0.06796776,"d":"0.0680"},"(-)"]
["DNA metabolism"]
[null,"Degradation of DNA",{"$nulls":13},{"v":0.12204797,"d":"0.1220"},"(-)"]
[null,"DNA replication, recombination, and repair",{"$nulls":7},{"v":0.2413735,"d":"0.2414"},"(-)",null,{"v":0.14930345,"d":"0.1493"},"(-)",null,{"v":0.21065773,"d":"0.2107"},"(-)"]
["Energy metabolism"]
[null,"Aerobic",null,{"v":0.0037873515,"d":"0.0038"},"(-)"]
[null,"Amino acids and amines",null,{"v":0.15649904,"d":"0.1565"},"(+)",null,{"v":0.1774931,"d":"0.1775"},"(+)"]
[null,"Anaerobic",null,{"v":0,"d":"0.0000"},"(+)",null,{"v":0,"d":"0.0000"},"(+)",null,{"v":0,"d":"0.0000"},"(+)",{"$nulls":4},{"v":0.22410175,"d":"0.2241"},"(+)"]
[null,"ATP-proton motive force interconversion",{"$nulls":7},{"v":0.0038627035,"d":"0.0039"},"(-)",null,{"v":0,"d":"0.0000"},"(-)",null,{"v":0,"d":"0.0000"},"(-)"]
[null,"Biosynthesis and degradation of polysaccharides",{"$nulls":4},{"v":0.1992934,"d":"0.1993"},"(+)"]
[null,"Fermentation",null,{"v":0.21770336,"d":"0.2177"},"(+)",null,{"v":0.002832277,"d":"0.0028"},"(+)",null,{"v":0,"d":"0.0000"},"(+)",null,{"v":0.003202556,"d":"0.0032"},"(+)",null,{"v":0.0029803985,"d":"0.0030"},"(+)"]
[null,"Glycolysis/gluconeogenesis",null,{"v":0.1999383,"d":"0.1999"},"(+)",null,{"v":0.013758421,"d":"0.0138"},"(+)"]
[null,"Other",{"$nulls":10},{"v":0.099578574,"d":"0.0996"},"(+)",null,{"v":0.17778343,"d":"0.1778"},"(+)"]
[null,"Pentose phosphate pathway",{"$nulls":4},{"v":0.17217356,"d":"0.1722"},"(+)"]
[null,"Pyruvate dehydrogenase",null,{"v":0.03249093,"d":"0.0325"},"(-)"]
[null,"Sugars",{"$nulls":10},{"v":0.22253886,"d":"0.2225"},"(+)"]
[null,"TCA cycle",null,{"v":0,"d":"0.0000"},"(-)",null,{"v":0.0014545455,"d":"0.0015"},"(-)"]
["Fatty acid and phospholipid metabolism"]
[null,"Biosynthesis",{"$nulls":10},{"v":0.2216033,"d":"0.2216"},"(-)"]
["Protein fate"]
[null,"Protein and peptide secretion and trafficking",null,{"v":0.16828461,"d":"0.1683"},"(+)",{"$nulls":4},{"v":0.023191683,"d":"0.0232"},"(-)",null,{"v":0.0055611026,"d":"0.0056"},"(-)",null,{"v":0.0015329238,"d":"0.0015"},"(-)"]
[null,"Protein folding and stabilization",{"$nulls":7},{"v":0.009174861,"d":"0.0092"},"(-)",null,{"v":0.026327917,"d":"0.0263"},"(-)",null,{"v":0.016011985,"d":"0.0160"},"(-)"]
[null,"Protein modification and repair",null,{"v":0.00088153424,"d":"0.0009"},"(+)",null,{"v":0,"d":"0.0000"},"(+)"]
["Protein synthesis"]
[null,"Ribosomal proteins: synthesis and modification",{"$nulls":7},{"v":0,"d":"0.0000"},"(-)",null,{"v":0,"d":"0.0000"},"(-)",null,{"v":0,"d":"0.0000"},"(-)"]
[null,"tRNA aminoacylation",{"$nulls":7},{"v":0.19644432,"d":"0.1964"},"(-)",null,{"v":0.00586319,"d":"0.0059"},"(-)",null,{"v":0.0029096785,"d":"0.0029"},"(-)"]
[null,"tRNA and rRNA base modification",{"$nulls":7},{"v":0.0011436573,"d":"0.0011"},"(-)",null,{"v":0,"d":"0.0000"},"(-)",null,{"v":0.00057708065,"d":"0.0006"},"(-)"]
["Purines, pyrimidines, nucleosides, and nucleotides"]
[null,"2'-Deoxyribonucleotide metabolism",null,{"v":0.09187678,"d":"0.0919"},"(+)",null,{"v":0.1276269,"d":"0.1276"},"(+)"]
[null,"Nucleotide and nucleoside interconversions",{"$nulls":7},{"v":0.04654965,"d":"0.0465"},"(-)",null,{"v":0.005975184,"d":"0.0060"},"(-)",null,{"v":0.015417952,"d":"0.0154"},"(-)"]
[null,"Purine ribonucleotide biosynthesis",null,{"v":0.17809951,"d":"0.1781"},"(+)",null,{"v":0.2075463,"d":"0.2075"},"(+)",null,{"v":0,"d":"0.0000"},"(-)",null,{"v":0,"d":"0.0000"},"(-)",null,{"v":0,"d":"0.0000"},"(-)"]
[null,"Pyrimidine ribonucleotide biosynthesis",{"$nulls":7},{"v":0.012355582,"d":"0.0124"},"(-)",null,{"v":0.014198877,"d":"0.0142"},"(-)",null,{"v":0.014502023,"d":"0.0145"},"(-)"]
["Transcription"]
[null,"Degradation of RNA",{"$nulls":10},{"v":0.24718414,"d":"0.2472"},"(-)",null,{"v":0.24706909,"d":"0.2471"},"(-)"]
[null,"DNA-dependent RNA polymerase",{"$nulls":10},{"v":0.114495516,"d":"0.1145"},"(-)",null,{"v":0.09149057,"d":"0.0915"},"(-)"]
[null,"RNA processing",{"$nulls":7},{"v":0.012588256,"d":"0.0126"},"(-)",null,{"v":0.0046459106,"d":"0.0046"},"(-)",null,{"v":0.001362599,"d":"0.0014"},"(-)"]
["Transport and binding proteins"]
[null,"Carbohydrates, organic alcohols, and acids",{"$nulls":7},{"v":0.17778325,"d":"0.1778"},"(+)",null,{"v":0.1069102,"d":"0.1069"},"(+)",null,{"v":0.23707865,"d":"0.2371"},"(+)"]
[null,"Cations and iron carrying compounds",null,{"v":0.23638213,"d":"0.2364"},"(+)",null,{"v":0.2044107,"d":"0.2044"},"(+)"]
[null,"Nucleosides, purines and pyrimidines",{"$nulls":10},{"v":0.17692842,"d":"0.1769"},"(-)",null,{"v":0.11286872,"d":"0.1129"},"(-)"]
["no role",{"$nulls":11},{"v":0.1502598,"d":"0.1503"},"(+)",null,{"v":0.20127042,"d":"0.2013"},"(+)"]
["other",null,null,{"v":0.086012825,"d":"0.0860"},"(-)",null,{"v":0.22162043,"d":"0.2216"},"(-)",null,{"v":0.0127016865,"d":"0.0127"},"(-)",null,{"v":0.022710864,"d":"0.0227"},"(-)",null,{"v":0.07979082,"d":"0.0798"},"(-)"]
[]
[null,"a Gene sets enriched in the top time point in the ratio are denoted with (+), and those sets enriched in the 3h sample are denoted with (-)."]
[null,"b Q-values are reported only for those comparisons where the Q-value was less than 0.25, indicating a significantly enriched gene set"]

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