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{"sheet":"S1","index":0,"n_rows":90,"n_cols":23,"rows_kept":90,"merged":[[0,0,0,9],[1,0,2,9],[5,0,5,4],[8,2,8,4],[47,0,47,9],[48,0,49,9],[77,1,77,4],[78,1,78,4],[79,1,79,4],[80,1,80,4],[82,1,82,4],[84,1,84,4],[89,0,91,9]],"flags":["formulas_cached_only"]}
[]
["Table S1.  Characteristics of FN and comparison patients matched on basis of original criteria in sSAP"]
[]
[{"$nulls":5},"FN Patients",null,"Comparison Patients",null,null,"rown","varname",{"$nulls":4},"stat1_0","stat2_0","stat1_1","stat2_1","pvalue","n0","n1"]
[{"$nulls":5},"(n=118)",null,"(n=118)",null,"p-value*",1,"counter",{"v":1829,"d":"1829.00"},null,{"v":1593,"d":"1593.00"},null,118,100,118,100,null,86,86]
["Demographics",{"$nulls":9},2]
[null,"Age, mean±SD, y",{"$nulls":3},"66.14 +/- 9.88",null,"65.91 +/- 9.85",null,0.3884496394,3,"age",60.190267906,13.903461047,59.598526703,14.200292338,66.144067797,9.8798555508,65.906779661,9.8501484115,0.3884496394,86,86]
[null,"Sex, %",{"$nulls":8},4]
[null,null,"Male",null,null,"56.78",null,"58.47",null,0.7728299927,5,"genderMale",56.096227447,null,55.739717618,null,56.779661017,null,58.474576271,null,0.7728299927,86,86]
[null,null,"Female",null,null,"43.22",null,"41.53",null,null,6,"genderFemale",43.903772553,null,44.260282382,null,43.220338983,null,41.525423729,null,0.7728299927,86,86]
[null,"Race, %",{"$nulls":8},7]
[null,null,"White/Caucasian",null,null,"70.34",null,"69.49",null,0.6216485167,8,"raceWhite",77.255330782,null,78.39165132,null,70.338983051,null,69.491525424,null,0.6216485167,86,86]
[null,null,"Asian",null,null,"0.00",null,"0.00",{"$nulls":3},"raceAsian",0.3827227993,null,0.4297114794]
[null,null,"Black/African-American",null,null,"0.00",null,"0.85",null,null,9,"raceBlack",0.8201202843,null,0.8594229589,{"$nulls":3},0.8474576271,null,0.6216485167,86,86]
[null,null,"Hispanic or Latino",null,null,"0.00",null,"0.85",{"$nulls":3},"raceHisp",0.2733734281,null,0.2455494168,{"$nulls":3},0.8474576271,null,0.6216485167]
[null,null,"Other",null,null,"2.54",null,"2.54",null,null,10,"raceOther",3.4445051941,null,3.5604665439,null,2.5423728814,null,2.5423728814,null,0.6216485167,86,86]
[null,null,"Missing",null,null,"27.12",null,"26.27",null,null,11,"raceMissing",17.823947512,null,16.513198281,null,27.118644068,null,26.271186441,null,0.6216485167,86,86]
[null,"Body Mass Index, mean±SD, kg/m2",{"$nulls":3},"25.53 +/- 4.49",null,"26.03 +/- 3.74",null,0.3895,12,"bbmi",25.676226498,4.5176908857,25.677725139,4.5594533831,25.53,4.49,26.03,3.74]
[null,"Country of Residence",{"$nulls":8},13,"country",{"$nulls":9},86,86]
[null,null,"Australia",null,null,"1.69",null,"1.69",null,"---",null,null,2.6790595954,null,2.8852056476,null,1.6949152542,null,1.6949152542]
[null,null,"Austria",null,null,"7.63",null,"7.63",{"$nulls":4},9.1306724986,null,9.1467157766,null,7.6271186441,null,7.6271186441]
[null,null,"Belgium",null,null,"11.02",null,"11.02",{"$nulls":4},9.6227446692,null,9.576427256,null,11.016949153,null,11.016949153]
[null,null,"France",null,null,"30.51",null,"30.51",{"$nulls":4},22.143247676,null,20.933087784,null,30.508474576,null,30.508474576]
[null,null,"Germany",null,null,"11.86",null,"11.86",{"$nulls":4},15.035538546,null,15.408225905,null,11.86440678,null,11.86440678]
[null,null,"Greece",null,null,"1.69",null,"1.69",{"$nulls":4},2.8430836523,null,3.0693677103,null,1.6949152542,null,1.6949152542]
[null,null,"Italy",null,null,"7.63",null,"7.63",{"$nulls":4},8.4745762712,null,8.5328422345,null,7.6271186441,null,7.6271186441]
[null,null,"Netherlands",null,null,"8.47",null,"8.47",{"$nulls":4},7.4357572444,null,7.489257213,null,8.4745762712,null,8.4745762712]
[null,null,"Nordics",null,null,"6.78",null,"6.78",{"$nulls":4},5.194095134,null,5.095150399,null,6.7796610169,null,6.7796610169]
[null,null,"Portugal",null,null,"0.00",null,"0.00",{"$nulls":4},3.2804811372,null,3.6832412523]
[null,null,"Spain",null,null,"8.47",null,"8.47",{"$nulls":4},7.927829415,null,7.6734192756,null,8.4745762712,null,8.4745762712]
[null,null,"Switzerland",null,null,"1.69",null,"1.69",{"$nulls":4},2.5697102242,null,2.7624309392,null,1.6949152542,null,1.6949152542]
[null,null,"UK & Ireland",null,null,"2.54",null,"2.54",{"$nulls":4},3.6632039366,null,3.7446286065,null,2.5423728814,null,2.5423728814]
["NHL, %"]
[null,"Histology",{"$nulls":8},14]
[null,null,"Follicular",null,null,"9.32",null,"9.32",null,"---",15,"histDiffuseLargeBCell",18.862766539,null,19.828115408,null,9.3220338983,null,9.3220338983,null,1,86,86]
[null,null,"Diffuse Large B Cell",null,null,"76.27",null,"76.27",{"$nulls":4},62.110442865,null,59.668508287,null,76.271186441,null,76.271186441,null,1]
[null,null,"Other",null,null,"14.41",null,"14.41",{"$nulls":4},19.026790596,null,20.503376304,null,14.406779661,null,14.406779661,null,1]
[null,"Tumor Stage",{"$nulls":8},18]
[null,null,"IA",null,null,"21.19",null,"21.19",null,"---",19,"tumor1A",15.910333516,null,15.162676489,null,21.186440678,null,21.186440678,null,null,86,86]
[null,null,"IB",null,null,"0.00",null,"0.00",null,null,20,"tumor1B",2.1869874248,null,2.4554941682,{"$nulls":6},86,86]
[null,null,"IIA",null,null,"8.47",null,"8.47",null,null,21,"tumor2A",13.61399672,null,14.180478821,null,8.4745762712,null,8.4745762712,null,null,86,86]
[null,null,"IIB",null,null,"4.24",null,"4.24",null,null,22,"tumor2B",5.5221432477,null,5.8317986495,null,4.2372881356,null,4.2372881356,null,null,86,86]
[null,null,"IIIA",null,null,"11.02",null,"11.02",null,null,23,"tumor3A",12.957900492,null,13.198281154,null,11.016949153,null,11.016949153,null,null,86,86]
[null,null,"IIIB",null,null,"7.63",null,"7.63",null,null,24,"tumor3B",8.1465281575,null,8.0417434009,null,7.6271186441,null,7.6271186441,null,null,86,86]
[null,null,"IVA",null,null,"29.66",null,"29.66",null,null,25,"tumor4A",25.478403499,null,25.414364641,null,29.661016949,null,29.661016949,null,null,86,86]
[null,null,"IVB",null,null,"17.80",null,"17.80",null,null,26,"tumor4B",15.85565883,null,15.346838551,null,17.796610169,null,17.796610169,null,null,86,86]
[null,null,"Missing",null,null,"0.00",null,"0.00",null,null,27,"tumorMissing",0.3280481137,null,0.3683241252,{"$nulls":6},86,86]
[]
["Table S1 (cont).  Characteristics of FN and comparison patients matched on basis of original criteria in sSAP"]
[]
[{"$nulls":5},"FN Patients",null,"Comparison Patients",null,null,"rown","varname",{"$nulls":4},"stat1_0","stat2_0","stat1_1","stat2_1","pvalue","n0","n1"]
[{"$nulls":5},"(n=118)",null,"(n=118)",null,"p-value*",1,"counter",{"v":1829,"d":"1829.00"},null,{"v":1593,"d":"1593.00"},null,118,100,118,100,null,86,86]
[null,"IPI/FLIPI Score"]
[null,null,"IPI Score",{"$nulls":7},30]
[{"$nulls":3},"Low",null,"17.76",null,"17.76",null,"---",31,"ipiLow",27.897574124,null,28.790199081,null,17.757009346,null,17.757009346,null,null,86,86]
[{"$nulls":3},"Intermediate",null,"55.14",null,"55.14",null,null,32,"ipiMed",46.495956873,null,45.329249617,null,55.140186916,null,55.140186916,null,null,86,86]
[{"$nulls":3},"High",null,"14.95",null,"14.95",null,null,33,"ipiHigh",10.714285714,null,10.336906585,null,14.953271028,null,14.953271028,null,null,86,86]
[{"$nulls":3},"Missing",null,"12.15",null,"12.15",null,null,34,"ipiMissing",14.892183288,null,15.543644717,null,12.14953271,null,12.14953271,null,null,86,86]
[null,null,"FLIPI Score"]
[{"$nulls":3},"Low-Risk",null,"9.09",null,"9.09",null,"---",null,null,12.173913043,null,12.383900929,null,9.0909090909,null,9.0909090909]
[{"$nulls":3},"Intermediate-Risk",null,"27.27",null,"27.27",{"$nulls":4},30.144927536,null,30.340557276,null,27.272727273,null,27.272727273]
[{"$nulls":3},"Poor-Risk",null,"63.64",null,"63.64",{"$nulls":4},42.608695652,null,41.176470588,null,63.636363636,null,63.636363636]
[{"$nulls":3},"Missing",null,"0.00",null,"0.00",{"$nulls":4},15.072463768,null,16.099071207]
[null,"Number of Extranodal Sites",{"$nulls":8},38]
[null,null,0,null,null,"33.05",null,"38.98",null,0.724394487,39,"exSites0",40.732640787,null,41.252302026,null,33.050847458,null,38.983050847,null,0.724394487,86,86]
[null,null,"1",null,null,"42.37",null,"35.59",null,null,40,"exSites1",33.95297977,null,33.026396562,null,42.372881356,null,35.593220339,null,0.724394487,86,86]
[null,null,"2",null,null,"12.71",null,"13.56",null,null,41,"exSites2",12.137780208,null,12.277470841,null,12.711864407,null,13.559322034,null,0.724394487,86,86]
[null,null,"3",null,null,"2.54",null,"4.24",null,null,42,"exSites3",5.3034445052,null,5.5862492327,null,2.5423728814,null,4.2372881356,null,0.724394487,86,86]
[null,null,"4",null,null,"1.69",null,"2.54",null,null,43,"exSites4",2.022963368,null,2.1485573972,null,1.6949152542,null,2.5423728814,null,0.724394487,86,86]
[null,null,"5",null,null,"7.63",null,"5.08",null,null,44,"exSites5",5.8501913614,null,5.7090239411,null,7.6271186441,null,5.0847457627,null,0.724394487,86,86]
[null,null,"Missing",null,null,"0.00",null,"0.00",null,null,45,"exSitesMissing",{"$nulls":9},86,86]
[null,"Bone Marrow Involvement",{"$nulls":3},"22.03",null,"22.03",null,0.8012519569,46,"BoneMarYes",25.97047567,null,26.580724371,null,22.033898305,null,22.033898305,null,0.8012519569,86,86]
["Risk of FN, %",{"$nulls":9},47]
[null,"<20%",{"$nulls":3},"33.05",null,"34.75",null,0.7680825619,48,"FnRiskLow",34.281027884,null,33.947206875,null,33.050847458,null,34.745762712,null,0.7680825619,86,86]
[null,">=20%",{"$nulls":3},"66.95",null,"65.25",null,null,49,"FnRiskHigh",65.281574631,null,65.561694291,null,66.949152542,null,65.254237288,null,0.7680825619,86,86]
[null,"Missing",{"$nulls":3},"0.00",null,"0.00",null,null,50,"FnRiskMissing",0.437397485,null,0.4910988336,{"$nulls":6},86,86]
["Medical Conditions, %",{"$nulls":9},51]
[null,"Cardiovascular Disease",{"$nulls":3},"30.51",null,"27.97",null,0.6682351418,52,"cmbCardiovascular",21.760524877,null,21.240024555,null,30.508474576,null,27.966101695,null,0.6682351418,86,86]
[null,"Respiratory Disease",{"$nulls":3},"7.63",null,"0.00",null,0.1824224395,53,"cmbRespiratory",4.2099507928,null,4.2971147944,null,7.6271186441,{"$nulls":3},0.1824224395,86,86]
[null,"Gastrointestinal Disease",{"$nulls":3},"6.78",null,"3.39",null,0.248213079,54,"cmbGastrointestinal",4.1552761072,null,4.1129527317,null,6.7796610169,null,3.3898305085,null,0.248213079,86,86]
[null,"Renal Disease",{"$nulls":3},"4.24",null,"1.69",null,0.256839258,55,"cmbRenal",2.1323127392,null,2.087170043,null,4.2372881356,null,1.6949152542,null,0.256839258,86,86]
[null,"Hepatic/Biliary Disease",{"$nulls":3},"3.39",null,"4.24",null,0.7388826804,56,"cmbHepatic",3.4991798797,null,3.3763044813,null,3.3898305085,null,4.2372881356,null,0.7388826804,86,86]
[null,"Haematologic/Lymphatic",{"$nulls":3},"3.39",null,"4.24",null,0.7054569861,57,"cmbHaematologic",2.733734281,null,2.5782688766,null,3.3898305085,null,4.2372881356,null,0.7054569861,86,86]
[null,"Immunologic",{"$nulls":3},"3.39",null,"2.54",null,0.7054569861,58,"cmbImmunologic",2.6790595954,null,2.701043585,null,3.3898305085,null,2.5423728814,null,0.7054569861,86,86]
[null,"Other",{"$nulls":3},"54.24",null,"44.92",null,0.1521214939,59,"cmbOther",40.623291416,null,39.963167587,null,54.237288136,null,44.915254237,null,0.1521214939,86,86]
["Therapies, %",{"$nulls":9},60]
[null,"Current Steroid Use",{"$nulls":3},"11.02",null,"12.71",null,0.6698153576,61,"RxSteroidUse",11.098961181,null,11.172498465,null,11.016949153,null,12.711864407,null,0.6698153576,86,86]
[null,"Prior Immunotherapy",{"$nulls":3},"3.39",null,"4.24",null,0.7388826804,62,"RxImmunoTherapy",3.608529251,null,3.6832412523,null,3.3898305085,null,4.2372881356,null,0.7388826804,86,86]
[null,"Prior Antineoplastic Therapy",{"$nulls":3},"7.63",null,"14.41",null,0.1024704349,63,"RxAntineoplastic",12.137780208,null,12.400245549,null,7.6271186441,null,14.406779661,null,0.1024704349,86,86]
["*p-values were not calculated for variables used in the matching process and for which there are no differences between groups (ie, there was an exact match)"]

{"sheet":"S1c","index":1,"n_rows":58,"n_cols":23,"rows_kept":58,"merged":[[0,0,0,9],[1,0,2,9],[50,0,52,9],[53,0,55,9]],"flags":["formulas_cached_only"]}
[]
["Table S1 (cont).  Characteristics of FN and comparison patients matched on basis of original criteria in sSAP"]
[]
[{"$nulls":5},"FN Patients",null,"Comparison Patients",null,null,"rown","varname",{"$nulls":4},"stat1_0","stat2_0","stat1_1","stat2_1","pvalue","n0","n1"]
[{"$nulls":5},"(n=118)",null,"(n=118)",null,"p-value*",1,"counter",{"v":1829,"d":"1829.00"},null,{"v":1593,"d":"1593.00"},null,{"v":118,"d":"118.00"},100,118,100,null,86,86]
["Chemotherapy Regimen, %",{"$nulls":9},2]
[null,"CHOP-14",{"$nulls":3},"0.00",null,"0.00",null,"---",3,"chop14",2.68,null,3.007980356,{"$nulls":6},86,86]
[null,"CHOP-14-R",{"$nulls":3},"25.42",null,"25.42",null,null,4,"chop14r",26.63,null,26.703499079,null,25.423728814,null,25.423728814,null,null,86,86]
[null,"CHOP-21",{"$nulls":3},"0.00",null,"0.00",null,null,5,"chop21",4.48,null,5.0337630448,{"$nulls":6},86,86]
[null,"CHOP-21-R",{"$nulls":3},"74.58",null,"74.58",null,null,6,"chop21r",66.21,null,65.25475752,null,74.576271186,null,74.576271186,null,null,86,86]
["Supportive Care, %",{"$nulls":9},7]
[null,"Index Cycle",{"$nulls":8},8]
[null,null,"G-CSF Prophylaxis",null,null,"49.15",null,"62.71",null,0.0094441657,9,"gcsfpr",{"v":46.746856206,"d":"46.75"},null,45.454545455,null,49.152542373,null,62.711864407,null,0.0094441657,86,86]
[null,null,"Anti-Infective FN Prophylaxis",null,null,"13.56",null,"8.47",null,0.2393165412,10,"aipr",{"v":8.5839256424,"d":"8.58"},null,7.0796460177,null,13.559322034,null,8.4745762712,null,0.2393165412,86,86]
[null,"Pre-Index Cycle",{"$nulls":8},11]
[null,null,"G-CSF",{"$nulls":7},12]
[{"$nulls":3},"Prophylaxis",null,"38.14",null,"38.14",null,"---",13,"pregcsfpr",{"$nulls":4},38.13559322,null,38.13559322,null,1,86,86]
[{"$nulls":3},"Treatment",null,"11.02",null,"11.02",null,"---",14,"pregcsftx",{"$nulls":4},11.016949153,null,11.016949153,null,1,86,86]
[null,null,"Anti-Infective",{"$nulls":7},15]
[{"$nulls":3},"FN Prophylaxis",null,"8.47",null,"8.47",null,"---",16,"preaipr",{"$nulls":4},8.4745762712,null,8.4745762712,null,1,86,86]
[{"$nulls":3},"FN Treatment",null,"3.39",null,"0.00",null,0.1024704349,17,"preaitx",{"$nulls":4},3.3898305085,{"$nulls":3},0.1024704349,86,86]
[null,null,"Transfusion",null,null,"0.00",null,"5.08",null,0,18,"Transf",{"$nulls":6},5.0847457627,null,null,86,86]
["ECOG PS, %",{"$nulls":9},19]
[null,0,{"$nulls":3},"57.63",null,"55.08",null,0.6218734243,20,"ecogps0",{"v":59.267359213,"d":"59.27"},null,59.361571516,null,57.627118644,null,55.084745763,null,0.6218734243,86,86]
[null,1,{"$nulls":3},"27.12",null,"32.20",null,null,21,"ecogps1",{"v":27.610716238,"d":"27.61"},null,27.378759975,null,27.118644068,null,32.203389831,null,0.3427817111,86,86]
[null,2,{"$nulls":3},"7.63",null,"4.24",null,null,22,"ecogps2",{"v":6.0688901039,"d":"6.07"},null,6.2001227747,null,7.6271186441,null,4.2372881356,null,0.1572992071,86,86]
[null,3,{"$nulls":3},"2.54",null,"0.85",null,null,23,"ecogps3",{"v":1.8589393111,"d":"1.86"},null,1.8416206262,null,2.5423728814,null,0.8474576271,null,0.1572992071,86,86]
[null,"4",{"$nulls":3},"0.00",null,"0.00",null,null,24,"ecogps4",{"v":0.437397485,"d":"0.44"},null,0.4910988336,null,0,null,0,null,0.3710933695,86,86]
[null,"Missing",{"$nulls":3},"5.08",null,"7.63",null,null,25,"ecogpsMissing",{"v":4.756697649,"d":"4.76"},null,4.7268262738,null,5.0847457627,null,7.6271186441,null,0.1797124949,86,86]
["Hematology"]
[null,"ANC (x10^9L), mean±SD",{"$nulls":3},"5.40±3.35",null,"5.60±2.77",null,0.5835996912,null,null,{"v":5.3968646,"d":"5.40"},{"v":3.3462739,"d":"3.35"},5.60049,{"v":2.7708205,"d":"2.77"},0.5835996912]
[null,"Presence of Anemia Symptoms, %",{"$nulls":3},"55.08",null,"50.00",null,0.4053805565,26,"anemiaSymptom",{"v":43.466375068,"d":"43.47"},null,42.357274401,null,55.084745763,null,50,null,0.4053805565,86,86]
["Index Cycle Number*",{"$nulls":9},27]
[null,"1",{"$nulls":3},"38.14",null,"38.14",null,"---",28,"idxCycle1",{"$nulls":4},38.13559322,null,38.13559322,null,null,86,86]
[null,"2",{"$nulls":3},"16.10",null,"16.10",null,null,29,"idxCycle2",{"$nulls":4},16.101694915,null,16.101694915,null,null,86,86]
[null,"3",{"$nulls":3},"11.02",null,"11.02",null,null,30,"idxCycle3",{"$nulls":4},11.016949153,null,11.016949153,null,null,86,86]
[null,"4",{"$nulls":3},"15.25",null,"15.25",null,null,31,"idxCycle4",{"$nulls":4},15.254237288,null,15.254237288,null,null,86,86]
[null,"5",{"$nulls":3},"9.32",null,"9.32",null,null,32,"idxCycle5",{"$nulls":4},9.3220338983,null,9.3220338983,null,null,86,86]
[null,"6",{"$nulls":3},"7.63",null,"7.63",null,null,33,"idxCycle6",{"$nulls":4},7.6271186441,null,7.6271186441,null,null,86,86]
[null,"7",{"$nulls":3},"2.54",null,"2.54",null,null,34,"idxCycle7",{"$nulls":4},2.5423728814,null,2.5423728814,null,null,86,86]
[null,"8",{"$nulls":3},"0.00",null,"0.00",null,null,35,"idxCycle8",{"$nulls":9},86,86]
["Total Number of Cycles (incl. index cycle thru end of course)",{"$nulls":9},36]
[null,"1",{"$nulls":3},"12.71",null,"6.78",null,0.9119146974,37,"Cycles1",{"$nulls":4},12.711864407,null,6.7796610169,null,0.9119146974,86,86]
[null,"2",{"$nulls":3},"14.41",null,"11.86",null,null,38,"Cycles2",{"$nulls":4},14.406779661,null,11.86440678,null,0.9119146974,86,86]
[null,"3",{"$nulls":3},"14.41",null,"12.71",null,null,39,"Cycles3",{"$nulls":4},14.406779661,null,12.711864407,null,0.9119146974,86,86]
[null,"4",{"$nulls":3},"10.17",null,"10.17",null,null,40,"Cycles4",{"$nulls":4},10.169491525,null,10.169491525,null,0.9119146974,86,86]
[null,"5",{"$nulls":3},"13.56",null,"14.41",null,null,41,"Cycles5",{"$nulls":4},13.559322034,null,14.406779661,null,0.9119146974,86,86]
[null,"6",{"$nulls":3},"16.95",null,"18.64",null,null,42,"Cycles6",{"$nulls":4},16.949152542,null,18.644067797,null,0.9119146974,86,86]
[null,"7",{"$nulls":3},"6.78",null,"6.78",null,null,43,"Cycles7",{"$nulls":4},6.7796610169,null,6.7796610169,null,0.9119146974,86,86]
[null,"8",{"$nulls":3},"11.02",null,"18.64",null,null,44,"Cycles8",{"$nulls":4},11.016949153,null,18.644067797,null,0.9119146974,86,86]
["*p-values were not calculated for variables used in the matching process and for which there are no differences between groups (ie, there was an exact match)"]
[]
[]
[]
[]
[]
[]
[{"$nulls":5}," "]

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[]
["Online Supplement -- Table S2.  UK-specific unit costs of FN-related care"]
[]
["Inpatient Care\nThe cost of FN inpatient care was estimated using hospital data from the 2009‐2010 National Health Service (NHS) Schedule of Reference Costs (for inpatient costs). All hospital admissions with the Healthcare Resource Group (HRG) Version 4 code for “Febrile Neutropenia with Malignancy” (PA45Z) were considered in calculations.  Admissions were stratified into three groups based on the length of stay (LOS)‐‐long‐stay, short-stay, or day‐case‐‐which was calculated as discharge date minus admission date.  (Thus, for patients admitted and discharged on the same date, LOS=0.) Long‐stay data were used for subjects with LOS ≥2 days, short‐stay data were used for subjects with LOS=1 day, and day‐case data were used for subjects with LOS=0 days.  (Because mean cost of day cases in the 2009‐2010 NHS Schedule was unduly influenced by one or more outliers [average=£2049, lower quartile=£261, upper quartile=£616], the value from the 2008‐2009 file was inflated to 2009-2010 levels and subsequently used in analyses.)\nThe (unit) cost of hospitalization was based on the corresponding HRG national average payment amount per admission.  The additional cost of “excess bed days” for IMPACT long‐stay subjects with hospital LOS that exceeded the national average (6.7) was included in the unit cost.  Use of individual healthcare services (e.g., antimicrobials, G-CSF) in the inpatient setting were not considered in costing FN-related hospitalizations.  \n\nOutpatient Care, Home Care, and Other Care\nThe cost of FN treated outside of the hospital setting was estimated by combining data on the assumed number of healthcare encounters during the episode and the corresponding cost of an encounter, which was estimated based on data from the 2010 Unit Costs of Health and Social Care Report (Personal Social Services Research Unit [PSSRU]).  Because data on the number of such encounters were not collected during the IMPACT study, in these analyses, each patient requiring FN outpatient care, home care, or other/unknown care, respectively, was assumed to require a minimum of two encounters (for initial diagnosis and final evaluation) in the corresponding setting of care.  Patients who received G-CSF during the cycle were assumed to require additional encounters, based on the number of administrations and the provider-specified location of administration.  Patients who received IV antimicrobial therapy during the cycle also were assumed to require additional encounters, based on the number of administrations and the designated setting of care for the FN event; for patients with FN requiring other/unknown care and for patients without an FN event in a given cycle, IV antimicrobial therapy was assumed to be administered in the outpatient setting.  To avoid double counting, patients receiving both G-CSF and IV antimicrobial therapy in the same setting of care were assumed to receive these agents on the same day, as appropriate; additional encounters were assumed for patients who received G-CSF and/or IV antimicrobial therapy in the designated setting of care for the FN event if and only if they had more than two such administrations.\nThe cost of the first outpatient encounter was estimated based on a weighted average of payments for “first‐attendance” consultations with physicians in the following specialties: clinical hematology, medical oncology, and clinical oncology; the cost of subsequent encounters was similarly estimated, based on a weighted‐average of payments for “follow‐up attendance” consultations.  The cost of a home care encounter was estimated based on the average payment for one‐hour visit from a nurse specialist.  The cost of encounters for patients whose setting of care was unknown was estimated based on the average payment for a community nurse.\n\nPharmacotherapy\nFN‐related drug costs‐‐including CSF agents and IV antimicrobial agents‐‐were estimated by combining corresponding estimated daily unit costs from the British National Formulary (BNF), 60th Edition, and duration of therapy data.  Average unit costs were assumed for agents for which corresponding information was not available in the BNF (e.g., because the drug is not reimbursed by NHS).\nFor filgrastim (5 mcg/kg), lenograstim (150 mcg/m2), and IV antimicrobial agents for which dosing is weight‐based, daily levels of utilization were determined using subjects’ baseline bodyweight or body surface area, as appropriate. For pegfilgrastim, the dose (one per cycle) was assumed to be 6 mg.  The daily cost of “other” G‐CSF agents was assumed to be the same as that for lenograstim. \n\n \n \n\n\n\n\n"]
{"$rows_empty":32}
["Healthcare Resource",{"$nulls":7},"Unit Cost (£)",null,"Source"]
["FN Inpatient Care"]
[null,"Long-Stay (per admission)",{"$nulls":6},5361,null,"NHS Reference Costs,\n2008-2009 and 2009-2010"]
[null,null,"Excess Bed Days (per day)",{"$nulls":5},502]
[null,"Short-Stay",{"$nulls":6},772]
[null,"Day Case",{"$nulls":6},577]
["FN Outpatient/Home/Other/Unknown Care"]
[null,"Outpatient Encounter"]
[null,null,"Initial Consultation",{"$nulls":5},177,null,"NHS Reference Costs,\n2009-2010"]
[null,null,"Follow-Up Consultation",{"$nulls":5},116]
[null,"Home Encounter",{"$nulls":6},84]
[null,"Other/Unknown Encounter",{"$nulls":6},26]
[null,"Drug*"]
[null,null,"Filgrastim (per 600 mcg)",{"$nulls":5},59,null,"BNF, 60th Edition"]
[null,null,"Pegfilgrastim (per 6 mg)",{"$nulls":5},686]
[null,null,"Other CSF (per day)",{"$nulls":5},63]
[null,null,"IV Antimicrobial Agents (per day)",{"$nulls":5},38]
["*Units and corresponding costs based on recommended dosing of agents"]

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[]
["Online Supplement -- Table S3.  Characteristics of FN patients and comparison patients matched on basis of age (+/- 5 years), tumor stage, chemotherapy regimen, and propensity score"]
[]
[{"$nulls":5},"FN Patients",null,"Comparison Patients",null,null,"rown","varname",{"$nulls":4},"stat1_0","stat2_0","stat1_1","stat2_1","pvalue","n0","n1"]
[{"$nulls":5},"(n=295)",null,"(n=295)",null,"p-value*",1,"counter",{"v":1829,"d":"1829.00"},null,{"v":1239,"d":"1239.00"},null,295,100,295,100,null,86,86]
["Demographics",{"$nulls":9},2]
[null,"Age, mean±SD, y",{"$nulls":3},"63.29 +/- 12.36",null,"62.98 +/- 12.14",null,0.1081644786,3,"age",60.190267906,13.903461047,58.784850927,14.413802614,63.285714286,12.363659178,62.982993197,12.139535018,0.1081644786,86,86]
[null,"Sex, %",{"$nulls":8},4]
[null,null,"Male",null,null,"48.98",null,"50.68",null,0.673699615,5,"genderMale",56.096227447,null,58.984689766,null,48.979591837,null,50.680272109,null,0.673699615,86,86]
[null,null,"Female",null,null,"51.02",null,"49.32",null,null,6,"genderFemale",43.903772553,null,41.015310234,null,51.020408163,null,49.319727891,null,0.673699615,86,86]
[null,"Race, %",{"$nulls":8},7]
[null,null,"White/Caucasian",null,null,"74.83",null,"81.63",null,0.6140399243,8,"raceWhite",77.255330782,null,76.792908944,null,74.829931973,null,81.632653061,null,0.6140399243,86,86]
[null,null,"Asian",null,null,"0.00",null,"0.00",{"$nulls":3},"raceAsian",0.3827227993,null,0.5640612409]
[null,null,"Black/African-American",null,null,"0.68",null,"0.34",null,null,9,"raceBlack",0.8201202843,null,0.9669621273,null,0.6802721088,null,0.3401360544,null,0.6140399243,86,86]
[null,null,"Hispanic or Latino",null,null,"0.34",null,"0.68",{"$nulls":3},"raceHisp",0.2733734281,null,0.1611603546,null,0.3401360544,null,0.6802721088,null,0.6140399243]
[null,null,"Other",null,null,"2.72",null,"2.04",null,null,10,"raceOther",3.4445051941,null,3.9484286865,null,2.7210884354,null,2.0408163265,null,0.6140399243,86,86]
[null,null,"Missing",null,null,"21.43",null,"15.31",null,null,11,"raceMissing",17.823947512,null,17.566478646,null,21.428571429,null,15.306122449,null,0.6140399243,86,86]
[null,"Body Mass Index, mean±SD, kg/m2",{"$nulls":3},"25.48 +/- 4.63",null,"25.30 +/- 4.30",null,0.6512471062,12,"bbmi",25.676226498,4.5176908857,25.814769667,4.536964452,25.481327645,4.6339202007,25.301211604,4.2975124546,0.6512471062]
[null,"Country of Residence",{"$nulls":8},13,"country",{"$nulls":9},86,86]
[null,null,"Australia",null,null,"2.72",null,"2.72",null,0.8169753379,null,null,2.6790595954,null,2.6591458501,null,2.7210884354,null,2.7210884354,null,0.8169753379]
[null,null,"Austria",null,null,"5.78",null,"9.18",{"$nulls":4},9.1306724986,null,9.7502014504,null,5.7823129252,null,9.1836734694,null,0.8169753379]
[null,null,"Belgium",null,null,"11.56",null,"11.90",{"$nulls":4},9.6227446692,null,8.6220789686,null,11.56462585,null,11.904761905,null,0.8169753379]
[null,null,"France",null,null,"24.49",null,"18.37",{"$nulls":4},22.143247676,null,22.48186946,null,24.489795918,null,18.367346939,null,0.8169753379]
[null,null,"Germany",null,null,"10.20",null,"12.24",{"$nulls":4},15.035538546,null,16.841257051,null,10.204081633,null,12.244897959,null,0.8169753379]
[null,null,"Greece",null,null,"2.72",null,"1.70",{"$nulls":4},2.8430836523,null,3.1426269138,null,2.7210884354,null,1.7006802721,null,0.8169753379]
[null,null,"Italy",null,null,"5.10",null,"7.82",{"$nulls":4},8.4745762712,null,9.4278807413,null,5.1020408163,null,7.8231292517,null,0.8169753379]
[null,null,"Netherlands",null,null,"8.84",null,"8.50",{"$nulls":4},7.4357572444,null,6.8493150685,null,8.843537415,null,8.5034013605,null,0.8169753379]
[null,null,"Nordics",null,null,"7.14",null,"6.46",{"$nulls":4},5.194095134,null,4.4319097502,null,7.1428571429,null,6.462585034,null,0.8169753379]
[null,null,"Portugal",null,null,"1.36",null,"1.70",{"$nulls":4},3.2804811372,null,4.1095890411,null,1.3605442177,null,1.7006802721,null,0.8169753379]
[null,null,"Spain",null,null,"12.59",null,"12.59",{"$nulls":4},7.927829415,null,5.8017727639,null,12.585034014,null,12.585034014,null,0.8169753379]
[null,null,"Switzerland",null,null,"2.72",null,"2.38",{"$nulls":4},2.5697102242,null,2.5785656728,null,2.7210884354,null,2.380952381,null,0.8169753379]
[null,null,"UK & Ireland",null,null,"4.76",null,"4.42",{"$nulls":4},3.6632039366,null,3.3037872683,null,4.7619047619,null,4.4217687075,null,0.8169753379]
["NHL, %"]
[null,"Histology",{"$nulls":8},14]
[null,null,"Follicular",null,null,"14.97",null,"13.27",null,0.8256142102,15,"histDiffuseLargeBCell",18.862766539,null,21.112006446,null,14.965986395,null,13.265306122,null,0.8256142102,86,86]
[null,null,"Diffuse Large B Cell",null,null,"67.01",null,"69.39",{"$nulls":4},62.110442865,null,59.387590653,null,67.006802721,null,69.387755102,null,0.8256142102]
[null,null,"Other",null,null,"18.03",null,"17.35",{"$nulls":4},19.026790596,null,19.500402901,null,18.027210884,null,17.346938776,null,0.8256142102]
[null,"Tumor Stage",{"$nulls":8},18]
[null,null,"IA",null,null,"12.59",null,"12.59",null,"---",19,"tumor1A",15.910333516,null,17.485898469,null,12.585034014,null,12.585034014,null,null,86,86]
[null,null,"IB",null,null,"2.04",null,"2.04",null,null,20,"tumor1B",2.1869874248,null,2.2562449637,null,2.0408163265,null,2.0408163265,null,null,86,86]
[null,null,"IIA",null,null,"10.54",null,"10.54",null,null,21,"tumor2A",13.61399672,null,15.068493151,null,10.544217687,null,10.544217687,null,null,86,86]
[null,null,"IIB",null,null,"6.12",null,"6.12",null,null,22,"tumor2B",5.5221432477,null,5.237711523,null,6.1224489796,null,6.1224489796,null,null,86,86]
[null,null,"IIIA",null,null,"10.54",null,"10.54",null,null,23,"tumor3A",12.957900492,null,14.020950846,null,10.544217687,null,10.544217687,null,null,86,86]
[null,null,"IIIB",null,null,"8.84",null,"8.84",null,null,24,"tumor3B",8.1465281575,null,7.8162771958,null,8.843537415,null,8.843537415,null,null,86,86]
[null,null,"IVA",null,null,"26.19",null,"26.19",null,null,25,"tumor4A",25.478403499,null,25.14101531,null,26.19047619,null,26.19047619,null,null,86,86]
[null,null,"IVB",null,null,"23.13",null,"23.13",null,null,26,"tumor4B",15.85565883,null,12.489927478,null,23.129251701,null,23.129251701,null,null,86,86]
[null,null,"Missing",null,null,"0.00",null,"0.00",null,null,27,"tumorMissing",0.3280481137,null,0.4834810637,{"$nulls":6},86,86]
[]
["Table S3 (cont).  Characteristics of FN patients and comparison patients matched on basis of age (+/- 5 years), tumor stage, chemotherapy regimen, and propensity score"]
[]
[{"$nulls":5},"FN Patients",null,"Comparison Patients",null,null,"rown","varname",{"$nulls":4},"stat1_0","stat2_0","stat1_1","stat2_1","pvalue","n0","n1"]
[{"$nulls":5},"(n=295)",null,"(n=295)",null,"p-value*",1,"counter",{"v":1829,"d":"1829.00"},null,{"v":1239,"d":"1239.00"},null,295,100,295,100,null,86,86]
["NHL, % (cont.)"]
[null,"IPI/FLIPI Score"]
[null,null,"IPI Score",{"$nulls":7},30]
[{"$nulls":3},"Low",null,"16.40",null,"20.78",null,0.3684273614,31,"ipiLow",27.897574124,null,32.686414709,null,16.4,null,20.784313725,null,0.3684273614,86,86]
[{"$nulls":3},"Intermediate",null,"50.40",null,"50.59",null,null,32,"ipiMed",46.495956873,null,44.330949949,null,50.4,null,50.588235294,null,0.3684273614,86,86]
[{"$nulls":3},"High",null,"19.60",null,"17.25",null,null,33,"ipiHigh",10.714285714,null,6.8437180797,null,19.6,null,17.254901961,null,0.3684273614,86,86]
[{"$nulls":3},"Missing",null,"13.60",null,"11.37",null,null,34,"ipiMissing",14.892183288,null,16.138917263,null,13.6,null,11.37254902,null,0.3684273614,86,86]
[null,null,"FLIPI Score"]
[{"$nulls":3},"Low-Risk",null,"11.36",null,"15.38",null,0.9196986029,null,null,12.173913043,null,11.832061069,null,11.363636364,null,15.384615385,null,0.9196986029]
[{"$nulls":3},"Intermediate-Risk",null,"36.36",null,"23.08",{"$nulls":4},30.144927536,null,30.152671756,null,36.363636364,null,23.076923077,null,0.9196986029]
[{"$nulls":3},"Poor-Risk",null,"43.18",null,"51.28",{"$nulls":4},42.608695652,null,41.221374046,null,43.181818182,null,51.282051282,null,0.9196986029]
[{"$nulls":3},"Missing",null,"9.09",null,"10.26",{"$nulls":4},15.072463768,null,16.79389313,null,9.0909090909,null,10.256410256,null,0.9196986029]
[null,"Number of Extranodal Sites",{"$nulls":8},38]
[null,null,0,null,null,"34.69",null,"35.37",null,0.9076239926,39,"exSites0",40.732640787,null,43.432715552,null,34.693877551,null,35.37414966,null,0.9076239926,86,86]
[null,null,"1",null,null,"36.39",null,"38.44",null,null,40,"exSites1",33.95297977,null,32.232070911,null,36.394557823,null,38.43537415,null,0.9076239926,86,86]
[null,null,"2",null,null,"12.59",null,"13.27",null,null,41,"exSites2",12.137780208,null,11.84528606,null,12.585034014,null,13.265306122,null,0.9076239926,86,86]
[null,null,"3",null,null,"6.80",null,"6.46",null,null,42,"exSites3",5.3034445052,null,4.673650282,null,6.8027210884,null,6.462585034,null,0.9076239926,86,86]
[null,null,"4",null,null,"2.72",null,"2.72",null,null,43,"exSites4",2.022963368,null,1.6921837228,null,2.7210884354,null,2.7210884354,null,0.9076239926,86,86]
[null,null,"5",null,null,"6.80",null,"3.74",null,null,44,"exSites5",5.8501913614,null,6.124093473,null,6.8027210884,null,3.7414965986,null,0.9076239926,86,86]
[null,null,"Missing",null,null,"0.00",null,"0.00",null,null,45,"exSitesMissing",{"$nulls":9},86,86]
[null,"Bone Marrow Involvement",{"$nulls":3},"29.59",null,"24.83",null,0.2523903859,46,"BoneMarYes",25.97047567,null,25.382755842,null,29.591836735,null,24.829931973,null,0.2523903859,86,86]
["Risk of FN, %",{"$nulls":9},47]
[null,"<20%",{"$nulls":3},"26.53",null,"26.19",null,0.5643073669,48,"FnRiskLow",34.281027884,null,38.114423852,null,26.530612245,null,26.19047619,null,0.5643073669,86,86]
[null,">=20%",{"$nulls":3},"73.13",null,"73.47",null,null,49,"FnRiskHigh",65.281574631,null,61.402095085,null,73.129251701,null,73.469387755,null,0.5643073669,86,86]
[null,"Missing",{"$nulls":3},"0.34",null,"0.34",null,null,50,"FnRiskMissing",0.437397485,null,0.4834810637,null,0.3401360544,null,0.3401360544,null,0.5643073669,86,86]
["Medical Conditions, %",{"$nulls":9},51]
[null,"Cardiovascular Disease",{"$nulls":3},"23.47",null,"25.17",null,0.6153025557,52,"cmbCardiovascular",21.760524877,null,20.467365028,null,23.469387755,null,25.170068027,null,0.6153025557,86,86]
[null,"Respiratory Disease",{"$nulls":3},"7.82",null,"4.76",null,0.1281901743,53,"cmbRespiratory",4.2099507928,null,3.1426269138,null,7.8231292517,null,4.7619047619,null,0.1281901743,86,86]
[null,"Gastrointestinal Disease",{"$nulls":3},"6.12",null,"5.10",null,0.5637028617,54,"cmbGastrointestinal",4.1552761072,null,3.4649476229,null,6.1224489796,null,5.1020408163,null,0.5637028617,86,86]
[null,"Renal Disease",{"$nulls":3},"3.06",null,"3.40",null,0.7962534147,55,"cmbRenal",2.1323127392,null,1.6116035455,null,3.0612244898,null,3.4013605442,null,0.7962534147,86,86]
[null,"Hepatic/Biliary Disease",{"$nulls":3},"2.72",null,"5.78",null,0.0605688602,56,"cmbHepatic",3.4991798797,null,3.0620467365,null,2.7210884354,null,5.7823129252,null,0.0605688602,86,86]
[null,"Haematologic/Lymphatic",{"$nulls":3},"5.10",null,"3.06",null,0.2206713619,57,"cmbHaematologic",2.733734281,null,2.0145044319,null,5.1020408163,null,3.0612244898,null,0.2206713619,86,86]
[null,"Immunologic",{"$nulls":3},"5.44",null,"3.74",null,0.3173105079,58,"cmbImmunologic",2.6790595954,null,1.8533440774,null,5.4421768707,null,3.7414965986,null,0.3173105079,86,86]
[null,"Other",{"$nulls":3},"48.98",null,"46.26",null,0.5049850751,59,"cmbOther",40.623291416,null,37.389202256,null,48.979591837,null,46.258503401,null,0.5049850751,86,86]
["Therapies, %",{"$nulls":9},60]
[null,"Current Steroid Use",{"$nulls":3},"17.35",null,"15.31",null,0.4460595494,61,"RxSteroidUse",11.098961181,null,8.7832393231,null,17.346938776,null,15.306122449,null,0.4460595494,86,86]
[null,"Prior Immunotherapy",{"$nulls":3},"3.74",null,"4.42",null,0.6698153576,62,"RxImmunoTherapy",3.608529251,null,3.3843674456,null,3.7414965986,null,4.4217687075,null,0.6698153576,86,86]
[null,"Prior Antineoplastic Therapy",{"$nulls":3},"12.93",null,"10.88",null,0.4601809354,63,"RxAntineoplastic",12.137780208,null,12.248186946,null,12.925170068,null,10.884353741,null,0.4601809354,86,86]
["*p-values were not calculated for variables used in the matching process and for which there are no differences between groups (ie, there was an exact match)"]

{"sheet":"S3c","index":4,"n_rows":51,"n_cols":23,"rows_kept":51,"merged":[[0,0,0,9],[1,0,2,9],[50,0,52,9],[53,0,55,9]],"flags":["formulas_cached_only"]}
[]
["Online Supplement -- Table S3 (cont.).  Characteristics of FN patients and comparison patients matched on basis of age (+/- 5 years), tumor stage, chemotherapy regimen, and propensity score"]
[]
[{"$nulls":5},"FN Patients",null,"Comparison Patients",null,null,"rown","varname",{"$nulls":4},"stat1_0","stat2_0","stat1_1","stat2_1","pvalue","n0","n1"]
[{"$nulls":5},"(n=295)",null,"(n=295)",null,"p-value*",1,"counter",{"v":1829,"d":"1829.00"},null,{"v":1239,"d":"1239.00"},null,295,100,295,100,null,86,86]
["Chemotherapy Regimen, %",{"$nulls":9},2]
[null,"CHOP-14",{"$nulls":3},"3.40",null,"3.40",null,"---",3,"chop14",2.68,null,2.336825141,null,3.4013605442,null,3.4013605442,null,null,86,86]
[null,"CHOP-14-R",{"$nulls":3},"27.89",null,"27.89",null,null,4,"chop14r",26.63,null,26.02739726,null,27.891156463,null,27.891156463,null,null,86,86]
[null,"CHOP-21",{"$nulls":3},"5.44",null,"5.44",null,null,5,"chop21",4.48,null,3.9484286865,null,5.4421768707,null,5.4421768707,null,null,86,86]
[null,"CHOP-21-R",{"$nulls":3},"63.27",null,"63.27",null,null,6,"chop21r",66.21,null,67.687348912,null,63.265306122,null,63.265306122,null,null,86,86]
["Supportive Care, %",{"$nulls":9},7]
[null,"Index Cycle",{"$nulls":8},8]
[null,null,"G-CSF Prophylaxis",null,null,"51.70",null,"56.46",null,0.1615133185,9,"gcsfpr",{"v":46.746856206,"d":"46.75"},null,45.454545455,null,51.700680272,null,56.462585034,null,0.1615133185,86,86]
[null,null,"Anti-Infective FN Prophylaxis",null,null,"13.27",null,"11.56",null,0.5287333251,10,"aipr",{"v":8.5839256424,"d":"8.58"},null,7.0796460177,null,13.265306122,null,11.56462585,null,0.5287333251,86,86]
[null,"Pre-Index Cycle",{"$nulls":8},11]
[null,null,"G-CSF",{"$nulls":7},12]
[{"$nulls":3},"Prophylaxis",null,"37.41",null,"41.84",null,0.0741498977,13,"pregcsfpr",{"$nulls":4},37.414965986,null,41.836734694,null,0.0741498977,86,86]
[{"$nulls":3},"Treatment",null,"9.52",null,"6.46",null,0.1281901743,14,"pregcsftx",{"$nulls":4},9.5238095238,null,6.462585034,null,0.1281901743,86,86]
[null,null,"Anti-Infective",{"$nulls":7},15]
[{"$nulls":3},"FN Prophylaxis",null,"7.82",null,"5.78",null,0.303483664,16,"preaipr",{"$nulls":4},7.8231292517,null,5.7823129252,null,0.303483664,86,86]
[{"$nulls":3},"FN Treatment",null,"1.70",null,"0.34",null,0.1024704349,17,"preaitx",{"$nulls":4},1.7006802721,null,0.3401360544,null,0.1024704349,86,86]
[null,null,"Transfusion",null,null,"9.52",null,"6.80",null,0.1441270348,18,"Transf",{"$nulls":4},9.5238095238,null,6.8027210884,null,0.1441270348,86,86]
["ECOG PS, %",{"$nulls":9},19]
[null,0,{"$nulls":3},"47.62",null,"52.38",null,0.1819262226,20,"ecogps0",{"v":59.267359213,"d":"59.27"},null,63.577759871,null,47.619047619,null,52.380952381,null,0.1819262226,86,86]
[null,1,{"$nulls":3},"30.95",null,"31.63",null,null,21,"ecogps1",{"v":27.610716238,"d":"27.61"},null,25.866236906,null,30.952380952,null,31.632653061,null,0.8514119676,86,86]
[null,2,{"$nulls":3},"10.20",null,"7.48",null,null,22,"ecogps2",{"v":6.0688901039,"d":"6.07"},null,4.8348106366,null,10.204081633,null,7.4829931973,null,0.227799994,86,86]
[null,3,{"$nulls":3},"5.10",null,"3.74",null,null,23,"ecogps3",{"v":1.8589393111,"d":"1.86"},null,0.6446414182,null,5.1020408163,null,3.7414965986,null,0.3710933695,86,86]
[null,"4",{"$nulls":3},"1.02",null,"0.68",null,null,24,"ecogps4",{"v":0.437397485,"d":"0.44"},null,0.2417405318,null,1.0204081633,null,0.6802721088,null,0.654720846,86,86]
[null,"Missing",{"$nulls":3},"5.10",null,"4.08",null,null,25,"ecogpsMissing",{"v":4.756697649,"d":"4.76"},null,4.8348106366,null,5.1020408163,null,4.0816326531,null,0.5485062355,86,86]
["Hematology"]
[null,"ANC (x10^9L), mean±SD",{"$nulls":3},"5.36±4.49",null,"5.66±3.40",null,0.793981581,null,null,{"v":5.3632259,"d":"5.36"},{"v":4.4854216,"d":"4.49"},5.6582408,{"v":3.3986614,"d":"3.40"},0.793981581]
[null,"Presence of Anemia Symptoms, %",{"$nulls":3},"56.80",null,"56.12",null,0.8563114607,26,"anemiaSymptom",{"v":43.466375068,"d":"43.47"},null,37.228041902,null,56.802721088,null,56.12244898,null,0.8563114607,86,86]
["Index Cycle Number*",{"$nulls":9},27]
[null,"1",{"$nulls":3},"42.86",null,"42.86",null,"---",28,"idxCycle1",{"$nulls":4},42.857142857,null,42.857142857,null,null,86,86]
[null,"2",{"$nulls":3},"13.61",null,"13.61",null,null,29,"idxCycle2",{"$nulls":4},13.605442177,null,13.605442177,null,null,86,86]
[null,"3",{"$nulls":3},"11.22",null,"11.22",null,null,30,"idxCycle3",{"$nulls":4},11.224489796,null,11.224489796,null,null,86,86]
[null,"4",{"$nulls":3},"12.24",null,"12.24",null,null,31,"idxCycle4",{"$nulls":4},12.244897959,null,12.244897959,null,null,86,86]
[null,"5",{"$nulls":3},"9.86",null,"9.86",null,null,32,"idxCycle5",{"$nulls":4},9.8639455782,null,9.8639455782,null,null,86,86]
[null,"6",{"$nulls":3},"8.16",null,"8.16",null,null,33,"idxCycle6",{"$nulls":4},8.1632653061,null,8.1632653061,null,null,86,86]
[null,"7",{"$nulls":3},"1.70",null,"1.70",null,null,34,"idxCycle7",{"$nulls":4},1.7006802721,null,1.7006802721,null,null,86,86]
[null,"8",{"$nulls":3},"0.34",null,"0.34",null,null,35,"idxCycle8",{"$nulls":4},0.3401360544,null,0.3401360544,null,null,86,86]
["Total Number of Cycles (incl. index cycle thru end of course)",{"$nulls":9},36]
[null,"1",{"$nulls":3},"10.58",null,"11.22",null,0.8116821617,37,"Cycles1",{"$nulls":4},10.580204778,null,11.224489796,null,0.8116821617,86,86]
[null,"2",{"$nulls":3},"11.95",null,"9.52",null,null,38,"Cycles2",{"$nulls":4},11.945392491,null,9.5238095238,null,0.8116821617,86,86]
[null,"3",{"$nulls":3},"13.31",null,"11.56",null,null,39,"Cycles3",{"$nulls":4},13.310580205,null,11.56462585,null,0.8116821617,86,86]
[null,"4",{"$nulls":3},"12.29",null,"15.31",null,null,40,"Cycles4",{"$nulls":4},12.28668942,null,15.306122449,null,0.8116821617,86,86]
[null,"5",{"$nulls":3},"12.63",null,"11.56",null,null,41,"Cycles5",{"$nulls":4},12.627986348,null,11.56462585,null,0.8116821617,86,86]
[null,"6",{"$nulls":3},"24.23",null,"24.83",null,null,42,"Cycles6",{"$nulls":4},24.232081911,null,24.829931973,null,0.8116821617,86,86]
[null,"7",{"$nulls":3},"4.10",null,"4.08",null,null,43,"Cycles7",{"$nulls":4},4.0955631399,null,4.0816326531,null,0.8116821617,86,86]
[null,"8",{"$nulls":3},"10.92",null,"11.90",null,null,44,"Cycles8",{"$nulls":4},10.921501706,null,11.904761905,null,0.8116821617,86,86]
["*p-values were not calculated for variables used in the matching process and for which there are no differences between groups (ie, there was an exact match)"]

{"sheet":"S4","index":5,"n_rows":90,"n_cols":23,"rows_kept":90,"merged":[[0,0,0,9],[1,0,2,9],[5,0,5,4],[8,2,8,4],[47,0,47,9],[48,0,49,9],[78,1,78,4],[79,1,79,4],[80,1,80,4],[81,1,81,4],[83,1,83,4],[85,1,85,4],[90,0,92,9]],"flags":["formulas_cached_only"]}
[]
["Online Supplement -- Table S4.  Characteristics of full patient population, unmatched patients, and matched patients"]
[]
[{"$nulls":5},"Full Patient Population",null,"Unmatched Patients",null,"Matched Patients","rown","varname",{"$nulls":4},"stat1_0","stat2_0","stat1_1","stat2_1","pvalue","n0","n1"]
[{"$nulls":5},"(n=1829)",null,"(n=1239)",null,"(n=590)",1,"counter",{"v":1829,"d":"1829.00"},null,{"v":1239,"d":"1239.00"},null,295,100,295,100,null,86,86]
["Demographics",{"$nulls":9},2]
[null,"Age, mean±SD, y",{"$nulls":3},"60.19 +/- 13.90",null,"58.78 +/- 14.41",null,"63.13 +/- 12.25",3,"age",60.190267906,13.903461047,58.784850927,14.413802614,63.285714286,12.363659178,62.982993197,12.139535018,0.1081644786,86,86]
[null,"Sex, %",{"$nulls":8},4]
[null,null,"Male",null,null,"56.10",null,"58.98",null,"49.83",5,"genderMale",56.096227447,null,58.984689766,null,48.979591837,null,50.680272109,null,0.673699615,86,86]
[null,null,"Female",null,null,"43.90",null,"41.02",null,"50.17",6,"genderFemale",43.903772553,null,41.015310234,null,51.020408163,null,49.319727891,null,0.673699615,86,86]
[null,"Race, %",{"$nulls":8},7]
[null,null,"White/Caucasian",null,null,"77.26",null,"76.79",null,"78.23",8,"raceWhite",77.255330782,null,76.792908944,null,74.829931973,null,81.632653061,null,0.6140399243,86,86]
[null,null,"Asian",null,null,"0.38",null,"0.56",null,"0.00",null,"raceAsian",0.3827227993,null,0.5640612409,null,0,null,0]
[null,null,"Black/African-American",null,null,"0.82",null,"0.97",null,"0.51",9,"raceBlack",0.8201202843,null,0.9669621273,null,0.6802721088,null,0.3401360544,null,0.6140399243,86,86]
[null,null,"Hispanic or Latino",null,null,"0.27",null,"0.16",null,"0.51",null,"raceHisp",0.2733734281,null,0.1611603546,null,0.3401360544,null,0.6802721088,null,0.6140399243]
[null,null,"Other",null,null,"3.44",null,"3.95",null,"2.38",10,"raceOther",3.4445051941,null,3.9484286865,null,2.7210884354,null,2.0408163265,null,0.6140399243,86,86]
[null,null,"Missing",null,null,"17.82",null,"17.57",null,"18.37",11,"raceMissing",17.823947512,null,17.566478646,null,21.428571429,null,15.306122449,null,0.6140399243,86,86]
[null,"Body Mass Index, mean±SD, kg/m2",{"$nulls":3},"25.68 +/- 4.52",null,"25.81 +/- 4.54",null,"25.39 +/- 4.47",12,"bbmi",25.676226498,4.5176908857,25.814769667,4.536964452,25.481327645,4.6339202007,25.301211604,4.2975124546,0.6512471062]
[null,"Country of Residence",{"$nulls":8},13,"country",{"$nulls":9},86,86]
[null,null,"Australia",null,null,"2.68",null,"2.66",null,"2.72",null,null,2.6790595954,null,2.6591458501,null,2.7210884354,null,2.7210884354,null,0.8169753379]
[null,null,"Austria",null,null,"9.13",null,"9.75",null,"7.48",null,null,9.1306724986,null,9.7502014504,null,5.7823129252,null,9.1836734694,null,0.8169753379]
[null,null,"Belgium",null,null,"9.62",null,"8.62",null,"11.73",null,null,9.6227446692,null,8.6220789686,null,11.56462585,null,11.904761905,null,0.8169753379]
[null,null,"France",null,null,"22.14",null,"22.48",null,"21.43",null,null,22.143247676,null,22.48186946,null,24.489795918,null,18.367346939,null,0.8169753379]
[null,null,"Germany",null,null,"15.04",null,"16.84",null,"11.22",null,null,15.035538546,null,16.841257051,null,10.204081633,null,12.244897959,null,0.8169753379]
[null,null,"Greece",null,null,"2.84",null,"3.14",null,"2.21",null,null,2.8430836523,null,3.1426269138,null,2.7210884354,null,1.7006802721,null,0.8169753379]
[null,null,"Italy",null,null,"8.47",null,"9.43",null,"6.46",null,null,8.4745762712,null,9.4278807413,null,5.1020408163,null,7.8231292517,null,0.8169753379]
[null,null,"Netherlands",null,null,"7.44",null,"6.85",null,"8.67",null,null,7.4357572444,null,6.8493150685,null,8.843537415,null,8.5034013605,null,0.8169753379]
[null,null,"Nordics",null,null,"5.19",null,"4.43",null,"6.80",null,null,5.194095134,null,4.4319097502,null,7.1428571429,null,6.462585034,null,0.8169753379]
[null,null,"Portugal",null,null,"3.28",null,"4.11",null,"1.53",null,null,3.2804811372,null,4.1095890411,null,1.3605442177,null,1.7006802721,null,0.8169753379]
[null,null,"Spain",null,null,"7.93",null,"5.80",null,"12.59",null,null,7.927829415,null,5.8017727639,null,12.585034014,null,12.585034014,null,0.8169753379]
[null,null,"Switzerland",null,null,"2.57",null,"2.58",null,"2.55",null,null,2.5697102242,null,2.5785656728,null,2.7210884354,null,2.380952381,null,0.8169753379]
[null,null,"UK & Ireland",null,null,"3.66",null,"3.30",null,"4.59",null,null,3.6632039366,null,3.3037872683,null,4.7619047619,null,4.4217687075,null,0.8169753379]
["NHL, %"]
[null,"Histology",{"$nulls":8},14]
[null,null,"Follicular",null,null,"18.86",null,"21.11",null,"14.12",15,"histDiffuseLargeBCell",18.862766539,null,21.112006446,null,14.965986395,null,13.265306122,null,0.8256142102,86,86]
[null,null,"Diffuse Large B Cell",null,null,"62.11",null,"59.39",null,"68.20",null,null,62.110442865,null,59.387590653,null,67.006802721,null,69.387755102,null,0.8256142102]
[null,null,"Other",null,null,"19.03",null,"19.50",null,"17.69",null,null,19.026790596,null,19.500402901,null,18.027210884,null,17.346938776,null,0.8256142102]
[null,"Tumor Stage",{"$nulls":8},18]
[null,null,"IA",null,null,"15.91",null,"17.49",null,"12.59",19,"tumor1A",15.910333516,null,17.485898469,null,12.585034014,null,12.585034014,null,null,86,86]
[null,null,"IB",null,null,"2.19",null,"2.26",null,"2.04",20,"tumor1B",2.1869874248,null,2.2562449637,null,2.0408163265,null,2.0408163265,null,null,86,86]
[null,null,"IIA",null,null,"13.61",null,"15.07",null,"10.54",21,"tumor2A",13.61399672,null,15.068493151,null,10.544217687,null,10.544217687,null,null,86,86]
[null,null,"IIB",null,null,"5.52",null,"5.24",null,"6.12",22,"tumor2B",5.5221432477,null,5.237711523,null,6.1224489796,null,6.1224489796,null,null,86,86]
[null,null,"IIIA",null,null,"12.96",null,"14.02",null,"10.54",23,"tumor3A",12.957900492,null,14.020950846,null,10.544217687,null,10.544217687,null,null,86,86]
[null,null,"IIIB",null,null,"8.15",null,"7.82",null,"8.84",24,"tumor3B",8.1465281575,null,7.8162771958,null,8.843537415,null,8.843537415,null,null,86,86]
[null,null,"IVA",null,null,"25.48",null,"25.14",null,"26.19",25,"tumor4A",25.478403499,null,25.14101531,null,26.19047619,null,26.19047619,null,null,86,86]
[null,null,"IVB",null,null,"15.86",null,"12.49",null,"23.13",26,"tumor4B",15.85565883,null,12.489927478,null,23.129251701,null,23.129251701,null,null,86,86]
[null,null,"Missing",null,null,"0.33",null,"0.48",null,"0.00",27,"tumorMissing",0.3280481137,null,0.4834810637,null,0,null,0,null,null,86,86]
[]
["Table S4 (cont).  Characteristics of full patient population, unmatched patients, and patients matched on basis of age (+/- 5 years), tumor stage, chemotherapy regimen, and propensity score"]
[]
[{"$nulls":5},"Full Patient Population",null,"Unmatched Patients",null,"Matched Patients","rown","varname",{"$nulls":4},"stat1_0","stat2_0","stat1_1","stat2_1","pvalue","n0","n1"]
[{"$nulls":5},"(n=1829)",null,"(n=1239)",null,"(n=590)",1,"counter",{"v":1829,"d":"1829.00"},null,{"v":1239,"d":"1239.00"},null,295,100,295,100,null,86,86]
["NHL, % (cont.)"]
[null,"IPI/FLIPI Score"]
[null,null,"IPI Score",{"$nulls":7},30]
[{"$nulls":3},"Low",null,"27.90",null,"32.69",null,"18.59",31,"ipiLow",27.897574124,null,32.686414709,null,16.4,null,20.784313725,null,0.3684273614,86,86]
[{"$nulls":3},"Intermediate",null,"46.50",null,"44.33",null,"50.49",32,"ipiMed",46.495956873,null,44.330949949,null,50.4,null,50.588235294,null,0.3684273614,86,86]
[{"$nulls":3},"High",null,"10.71",null,"6.84",null,"18.43",33,"ipiHigh",10.714285714,null,6.8437180797,null,19.6,null,17.254901961,null,0.3684273614,86,86]
[{"$nulls":3},"Missing",null,"14.89",null,"16.14",null,"12.49",34,"ipiMissing",14.892183288,null,16.138917263,null,13.6,null,11.37254902,null,0.3684273614,86,86]
[null,null,"FLIPI Score"]
[{"$nulls":3},"Low-Risk",null,"12.17",null,"11.83",null,"13.37",null,null,12.173913043,null,11.832061069,null,11.363636364,null,15.384615385,null,0.9196986029]
[{"$nulls":3},"Intermediate-Risk",null,"30.14",null,"30.15",null,"29.72",null,null,30.144927536,null,30.152671756,null,36.363636364,null,23.076923077,null,0.9196986029]
[{"$nulls":3},"Poor-Risk",null,"42.61",null,"41.22",null,"47.23",null,null,42.608695652,null,41.221374046,null,43.181818182,null,51.282051282,null,0.9196986029]
[{"$nulls":3},"Missing",null,"15.07",null,"16.79",null,"9.67",null,null,15.072463768,null,16.79389313,null,9.0909090909,null,10.256410256,null,0.9196986029]
[null,"Number of Extranodal Sites",{"$nulls":8},38]
[null,null,0,null,null,"40.73",null,"43.43",null,"35.03",39,"exSites0",40.732640787,null,43.432715552,null,34.693877551,null,35.37414966,null,0.9076239926,86,86]
[null,null,"1",null,null,"33.95",null,"32.23",null,"37.41",40,"exSites1",33.95297977,null,32.232070911,null,36.394557823,null,38.43537415,null,0.9076239926,86,86]
[null,null,"2",null,null,"12.14",null,"11.85",null,"12.93",41,"exSites2",12.137780208,null,11.84528606,null,12.585034014,null,13.265306122,null,0.9076239926,86,86]
[null,null,"3",null,null,"5.30",null,"4.67",null,"6.63",42,"exSites3",5.3034445052,null,4.673650282,null,6.8027210884,null,6.462585034,null,0.9076239926,86,86]
[null,null,"4",null,null,"2.02",null,"1.69",null,"2.72",43,"exSites4",2.022963368,null,1.6921837228,null,2.7210884354,null,2.7210884354,null,0.9076239926,86,86]
[null,null,"5",null,null,"5.85",null,"6.12",null,"5.27",44,"exSites5",5.8501913614,null,6.124093473,null,6.8027210884,null,3.7414965986,null,0.9076239926,86,86]
[null,null,"Missing",null,null,"0.00",null,"0.00",null,"0.00",45,"exSitesMissing",{"$nulls":4},0,null,0,null,null,86,86]
[null,"Bone Marrow Involvement",{"$nulls":3},"25.97",null,"25.38",null,"27.21",46,"BoneMarYes",25.97047567,null,25.382755842,null,29.591836735,null,24.829931973,null,0.2523903859,86,86]
["Risk of FN, %",{"$nulls":9},47]
[null,"<20%",{"$nulls":3},"34.28",null,"38.11",null,"26.36",48,"FnRiskLow",34.281027884,null,38.114423852,null,26.530612245,null,26.19047619,null,0.5643073669,86,86]
[null,">=20%",{"$nulls":3},"65.28",null,"61.40",null,"73.30",49,"FnRiskHigh",65.281574631,null,61.402095085,null,73.129251701,null,73.469387755,null,0.5643073669,86,86]
[null,"Missing",{"$nulls":3},"0.44",null,"0.48",null,"0.34",50,"FnRiskMissing",0.437397485,null,0.4834810637,null,0.3401360544,null,0.3401360544,null,0.5643073669,86,86]
["Medical Conditions, %",{"$nulls":9},51]
[null,"Cardiovascular Disease",{"$nulls":3},"21.76",null,"20.47",null,"24.32",52,"cmbCardiovascular",21.760524877,null,20.467365028,null,23.469387755,null,25.170068027,null,0.6153025557,86,86]
[null,"Respiratory Disease",{"$nulls":3},"4.21",null,"3.14",null,"6.29",53,"cmbRespiratory",4.2099507928,null,3.1426269138,null,7.8231292517,null,4.7619047619,null,0.1281901743,86,86]
[null,"Gastrointestinal Disease",{"$nulls":3},"4.16",null,"3.46",null,"5.61",54,"cmbGastrointestinal",4.1552761072,null,3.4649476229,null,6.1224489796,null,5.1020408163,null,0.5637028617,86,86]
[null,"Renal Disease",{"$nulls":3},"2.13",null,"1.61",null,"3.23",55,"cmbRenal",2.1323127392,null,1.6116035455,null,3.0612244898,null,3.4013605442,null,0.7962534147,86,86]
[null,"Hepatic/Biliary Disease",{"$nulls":3},"3.50",null,"3.06",null,"4.25",56,"cmbHepatic",3.4991798797,null,3.0620467365,null,2.7210884354,null,5.7823129252,null,0.0605688602,86,86]
[null,"Haematologic/Lymphatic",{"$nulls":3},"2.73",null,"2.01",null,"4.08",57,"cmbHaematologic",2.733734281,null,2.0145044319,null,5.1020408163,null,3.0612244898,null,0.2206713619,86,86]
[null,"Immunologic",{"$nulls":3},"2.68",null,"1.85",null,"4.59",58,"cmbImmunologic",2.6790595954,null,1.8533440774,null,5.4421768707,null,3.7414965986,null,0.3173105079,86,86]
[null,"Other",{"$nulls":3},"40.62",null,"37.39",null,"47.62",59,"cmbOther",40.623291416,null,37.389202256,null,48.979591837,null,46.258503401,null,0.5049850751,86,86]
["Therapies, %",{"$nulls":9},60]
[null,"Current Steroid Use",{"$nulls":3},"11.10",null,"8.78",null,"16.33",61,"RxSteroidUse",11.098961181,null,8.7832393231,null,17.346938776,null,15.306122449,null,0.4460595494,86,86]
[null,"Prior Immunotherapy",{"$nulls":3},"3.61",null,"3.38",null,"4.08",62,"RxImmunoTherapy",3.608529251,null,3.3843674456,null,3.7414965986,null,4.4217687075,null,0.6698153576,86,86]
[null,"Prior Antineoplastic Therapy",{"$nulls":3},"12.14",null,"12.25",null,"11.90",63,"RxAntineoplastic",12.137780208,null,12.248186946,null,12.925170068,null,10.884353741,null,0.4601809354,86,86]

{"sheet":"S4c","index":6,"n_rows":50,"n_cols":23,"rows_kept":50,"merged":[[0,0,0,9],[1,0,2,9],[50,0,52,9],[53,0,55,9]],"flags":["formulas_cached_only"]}
[]
["Table S4 (cont).  Characteristics of full patient population, unmatched patients, and patients matched on basis of age (+/- 5 years), tumor stage, chemotherapy regimen, and propensity score"]
[]
[{"$nulls":5},"Full Patient Population",null,"Unmatched Patients",null,"Matched Patients","rown","varname",{"$nulls":4},"stat1_0","stat2_0","stat1_1","stat2_1","pvalue","n0","n1"]
[{"$nulls":5},"(n=1829)",null,"(n=1239)",null,"(n=590)",1,"counter",{"v":1829,"d":"1829.00"},null,{"v":1239,"d":"1239.00"},null,295,100,295,100,null,86,86]
["Chemotherapy Regimen, %",{"$nulls":9},2]
[null,"CHOP-14",{"$nulls":3},"2.68",null,"2.34",null,"3.40",3,"chop14",2.68,null,2.336825141,null,3.4013605442,null,3.4013605442,null,null,86,86]
[null,"CHOP-14-R",{"$nulls":3},"26.63",null,"26.03",null,"27.89",4,"chop14r",26.63,null,26.02739726,null,27.891156463,null,27.891156463,null,null,86,86]
[null,"CHOP-21",{"$nulls":3},"4.48",null,"3.95",null,"5.44",5,"chop21",4.48,null,3.9484286865,null,5.4421768707,null,5.4421768707,null,null,86,86]
[null,"CHOP-21-R",{"$nulls":3},"66.21",null,"67.69",null,"63.27",6,"chop21r",66.21,null,67.687348912,null,63.265306122,null,63.265306122,null,null,86,86]
["Supportive Care, %",{"$nulls":9},7]
[null,"Index Cycle",{"$nulls":8},8]
[null,null,"G-CSF Prophylaxis",null,null,"46.75",null,"45.45",null,"54.08",9,"gcsfpr",{"v":46.746856206,"d":"46.75"},null,45.454545455,null,51.700680272,null,56.462585034,null,0.1615133185,86,86]
[null,null,"Anti-Infective FN Prophylaxis",null,null,"8.58",null,"7.08",null,"12.41",10,"aipr",{"v":8.5839256424,"d":"8.58"},null,7.0796460177,null,13.265306122,null,11.56462585,null,0.5287333251,86,86]
[null,"Pre-Index Cycle",{"$nulls":8},11]
[null,null,"G-CSF",{"$nulls":7},12]
[{"$nulls":3},"Prophylaxis",null,"---",null,"---",null,"39.63",13,"pregcsfpr",{"$nulls":4},37.414965986,null,41.836734694,null,0.0741498977,86,86]
[{"$nulls":3},"Treatment",null,"---",null,"---",null,"7.99",14,"pregcsftx",{"$nulls":4},9.5238095238,null,6.462585034,null,0.1281901743,86,86]
[null,null,"Anti-Infective",{"$nulls":7},15]
[{"$nulls":3},"FN Prophylaxis",null,"---",null,"---",null,"6.80",16,"preaipr",{"$nulls":4},7.8231292517,null,5.7823129252,null,0.303483664,86,86]
[{"$nulls":3},"FN Treatment",null,"---",null,"---",null,"1.02",17,"preaitx",{"$nulls":4},1.7006802721,null,0.3401360544,null,0.1024704349,86,86]
[null,null,"Transfusion",null,null,"---",null,"---",null,"8.16",18,"Transf",{"$nulls":4},9.5238095238,null,6.8027210884,null,0.1441270348,86,86]
["ECOG PS, %",{"$nulls":9},19]
[null,0,{"$nulls":3},"59.27",null,"63.58",null,"50.00",20,"ecogps0",{"v":59.267359213,"d":"59.27"},null,63.577759871,null,47.619047619,null,52.380952381,null,0.1819262226,86,86]
[null,1,{"$nulls":3},"27.61",null,"25.87",null,"31.29",21,"ecogps1",{"v":27.610716238,"d":"27.61"},null,25.866236906,null,30.952380952,null,31.632653061,null,0.8514119676,86,86]
[null,2,{"$nulls":3},"6.07",null,"4.83",null,"8.84",22,"ecogps2",{"v":6.0688901039,"d":"6.07"},null,4.8348106366,null,10.204081633,null,7.4829931973,null,0.227799994,86,86]
[null,3,{"$nulls":3},"1.86",null,"0.64",null,"4.42",23,"ecogps3",{"v":1.8589393111,"d":"1.86"},null,0.6446414182,null,5.1020408163,null,3.7414965986,null,0.3710933695,86,86]
[null,"4",{"$nulls":3},"0.44",null,"0.24",null,"0.85",24,"ecogps4",{"v":0.437397485,"d":"0.44"},null,0.2417405318,null,1.0204081633,null,0.6802721088,null,0.654720846,86,86]
[null,"Missing",{"$nulls":3},"4.76",null,"4.83",null,"4.59",25,"ecogpsMissing",{"v":4.756697649,"d":"4.76"},null,4.8348106366,null,5.1020408163,null,4.0816326531,null,0.5485062355,86,86]
["Hematology"]
[null,"ANC (x10^9L), mean±SD",{"$nulls":3},"5.46±3.73",null,"5.44±3.62",null,"5.51±3.97",null,null,{"v":5.4636248,"d":"5.46"},{"v":3.7348635,"d":"3.73"},5.4400805,{"v":3.6174505,"d":"3.62"},5.512562,3.9712405]
[null,"Presence of Anemia Symptoms, %",{"$nulls":3},"43.47",null,"37.23",null,"56.46",26,"anemiaSymptom",{"v":43.466375068,"d":"43.47"},null,37.228041902,null,56.802721088,null,56.12244898,null,0.8563114607,86,86]
["Index Cycle Number*",{"$nulls":9},27]
[null,"1",{"$nulls":3},"---",null,"---",null,"42.86",28,"idxCycle1",{"$nulls":4},42.857142857,null,42.857142857,null,null,86,86]
[null,"2",{"$nulls":3},"---",null,"---",null,"13.61",29,"idxCycle2",{"$nulls":4},13.605442177,null,13.605442177,null,null,86,86]
[null,"3",{"$nulls":3},"---",null,"---",null,"11.22",30,"idxCycle3",{"$nulls":4},11.224489796,null,11.224489796,null,null,86,86]
[null,"4",{"$nulls":3},"---",null,"---",null,"12.24",31,"idxCycle4",{"$nulls":4},12.244897959,null,12.244897959,null,null,86,86]
[null,"5",{"$nulls":3},"---",null,"---",null,"9.86",32,"idxCycle5",{"$nulls":4},9.8639455782,null,9.8639455782,null,null,86,86]
[null,"6",{"$nulls":3},"---",null,"---",null,"8.16",33,"idxCycle6",{"$nulls":4},8.1632653061,null,8.1632653061,null,null,86,86]
[null,"7",{"$nulls":3},"---",null,"---",null,"1.70",34,"idxCycle7",{"$nulls":4},1.7006802721,null,1.7006802721,null,null,86,86]
[null,"8",{"$nulls":3},"---",null,"---",null,"0.34",35,"idxCycle8",{"$nulls":4},0.3401360544,null,0.3401360544,null,null,86,86]
["Total Number of Cycles (incl. index cycle thru end of course)",{"$nulls":9},36]
[null,"1",{"$nulls":3},"---",null,"---",null,"10.90",37,"Cycles1",{"$nulls":4},10.580204778,null,11.224489796,null,0.8116821617,86,86]
[null,"2",{"$nulls":3},"---",null,"---",null,"10.73",38,"Cycles2",{"$nulls":4},11.945392491,null,9.5238095238,null,0.8116821617,86,86]
[null,"3",{"$nulls":3},"---",null,"---",null,"12.44",39,"Cycles3",{"$nulls":4},13.310580205,null,11.56462585,null,0.8116821617,86,86]
[null,"4",{"$nulls":3},"---",null,"---",null,"13.80",40,"Cycles4",{"$nulls":4},12.28668942,null,15.306122449,null,0.8116821617,86,86]
[null,"5",{"$nulls":3},"---",null,"---",null,"12.10",41,"Cycles5",{"$nulls":4},12.627986348,null,11.56462585,null,0.8116821617,86,86]
[null,"6",{"$nulls":3},"---",null,"---",null,"24.53",42,"Cycles6",{"$nulls":4},24.232081911,null,24.829931973,null,0.8116821617,86,86]
[null,"7",{"$nulls":3},"---",null,"---",null,"4.09",43,"Cycles7",{"$nulls":4},4.0955631399,null,4.0816326531,null,0.8116821617,86,86]
[null,"8",{"$nulls":3},"---",null,"---",null,"11.41",44,"Cycles8",{"$nulls":4},10.921501706,null,11.904761905,null,0.8116821617,86,86]

{"sheet":"S5","index":7,"n_rows":154,"n_cols":61,"rows_kept":154,"merged":[[0,0,0,16],[1,0,2,16],[3,6,3,16],[5,6,5,8],[5,10,5,12],[5,14,5,16],[45,0,45,16],[46,0,47,16],[48,6,48,16],[50,6,50,8],[50,10,50,12],[50,14,50,16],[81,0,81,16],[82,0,83,16],[84,6,84,16],[86,6,86,8],[86,10,86,12],[86,14,86,16],[126,0,126,16],[127,0,128,16],[129,6,129,16],[131,6,131,8],[131,10,131,12],[131,14,131,16],[153,0,154,16]],"flags":["formulas_cached_only"]}
[]
["Online Supplement -- Table S5.  Healthcare utilization among FN patients and matched comparison patients matched, by country"]
[]
[{"$nulls":6},"Mean (95% CI)"]
[]
[{"$nulls":6},"Overall*",{"$nulls":3},"Index Cycle",{"$nulls":3},"Post-Index Cycles"]
[]
[{"$nulls":6},"FN","Comparison",null,null,"FN","Comparison",null,null,"FN","Comparison"]
["Healthcare Resources",{"$nulls":5},"Patients","Patients","Difference",null,"Patients","Patients","Difference",null,"Patients","Patients","Difference","rown","varname","stat1","stat12_5","stat197_5","stat2",null,"stat22_5","stat297_5",{"$nulls":5},"stat3","stat32_5","stat397_5","stat4",null,"stat42_5","stat497_5",{"$nulls":5},"stat5","stat52_5","stat597_5","stat6",null,"stat62_5","stat697_5"]
["Australia (n=5)"]
[null,"No. of FN Events",{"$nulls":4},"1.80 (1.00,3.40)","0.00 (0.00,0.00)","1.80 (1.00,3.40)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.80 (0.00,2.40)","0.00 (0.00,0.00)","0.80 (0.00,2.40)",2,"fnevent",0,1.8024,1.8008,0,0,0,1,1.8,3.4,1,1.8,3.4,0,1,1,0,0,0,1,1,1,1,1,1,0,0.8024,0.8008,0,0,0,0,0.8,2.4,0,0.8,2.4]
[null,null,"Requiring Inpatient Care",{"$nulls":3},"1.80 (1.00,3.40)","0.00 (0.00,0.00)","1.80 (1.00,3.40)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.80 (0.00,2.40)","0.00 (0.00,0.00)","0.80 (0.00,2.40)",3,"fnhosp",0,1.8024,1.8008,0,0,0,1,1.8,3.4,1,1.8,3.4,0,1,1,0,0,0,1,1,1,1,1,1,0,0.8024,0.8008,0,0,0,0,0.8,2.4,0,0.8,2.4,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Outpatient Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",4,"fnout",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Home Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",5,"fnhome",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Other Care/No Action",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",6,"fnoth",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Unknown Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"fnunkn",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
[null,"FN-Related Inpatient Care",{"$nulls":15},7,null,2.8008,3.2002,0.4068,1.8,2.8,4.2,1.8,3.2,4.6,-2,0.4,2.8,1,1,0,1,1,1,1,1,1,0,0,0,1.8008,2.2002,0.4068,0.8,1.8,3.2,0.8,2.2,3.6,-2,0.4,2.8]
[null,null,"Days in Hospital",{"$nulls":3},"3.20 (1.80,4.60)","2.80 (1.80,4.20)","0.41 (-2.00,2.80)",null,"1.00 (1.00,1.00)","1.00 (1.00,1.00)","1.00 (1.00,1.00)",null,"2.20 (0.80,3.60)","1.80 (0.80,3.20)","0.41 (-2.00,2.80)",8,"hospdays",2.8008,3.2002,0.4068,1.8,2.8,4.2,1.8,3.2,4.6,-2,0.4,2.8,1,1,0,1,1,1,1,1,1,0,0,0,1.8008,2.2002,0.4068,0.8,1.8,3.2,0.8,2.2,3.6,-2,0.4,2.8,null,2.8007999999999997,true,{"v":0,"d":"0.0000"}]
["Austria (n=13)"]
[null,"No. of FN Events",{"$nulls":4},"1.69 (1.23,2.27)","0.16 (0.00,0.46)","1.54 (1.08,2.15)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.69 (0.23,1.27)","0.16 (0.00,0.46)","0.54 (0.08,1.15)",2,"fnevent",0.1558461538,1.6930769231,1.5390769231,0,0.1538461538,0.4615384615,1.2307692308,1.6923076923,2.2692307692,1.0769230769,1.5384615385,2.1538461538,0,1,1,0,0,0,1,1,1,1,1,1,0.1558461538,0.6930769231,0.5390769231,0,0.1538461538,0.4615384615,0.2307692308,0.6923076923,1.2692307692,0.0769230769,0.5384615385,1.1538461538]
[null,null,"Requiring Inpatient Care",{"$nulls":3},"1.31 (0.85,1.92)","0.16 (0.00,0.46)","1.15 (0.69,1.77)",null,"0.77 (0.54,1.00)","0.00 (0.00,0.00)","0.77 (0.54,1.00)",null,"0.54 (0.15,1.08)","0.16 (0.00,0.46)","0.38 (-0.08,0.92)",3,"fnhosp",0.1558461538,1.3096153846,1.1533846154,0,0.1538461538,0.4615384615,0.8461538462,1.3076923077,1.9230769231,0.6923076923,1.1538461538,1.7692307692,0,0.7699230769,0.7686923077,0,0,0,0.5384615385,0.7692307692,1,0.5384615385,0.7692307692,1,0.1558461538,0.5396923077,0.3846923077,0,0.1538461538,0.4615384615,0.1538461538,0.5384615385,1.0769230769,-0.076923077,0.3846153846,0.9230769231,null,0.1558461538,true,{"v":0,"d":"0.0000"},null,0.7735120399621965]
[null,null,"Requiring Outpatient Care",{"$nulls":3},"0.08 (0.00,0.23)","0.00 (0.00,0.00)","0.08 (0.00,0.23)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.08 (0.00,0.23)","0.00 (0.00,0.00)","0.08 (0.00,0.23)",4,"fnout",0,0.0770769231,0.0770769231,0,0,0,0,0.0769230769,0.2307692308,0,0.0769230769,0.2307692308,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0770769231,0.0770769231,0,0,0,0,0.0769230769,0.2307692308,0,0.0769230769,0.2307692308,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Home Care",{"$nulls":3},"0.15 (0.00,0.46)","0.00 (0.00,0.00)","0.15 (0.00,0.46)",null,"0.08 (0.00,0.23)","0.00 (0.00,0.00)","0.08 (0.00,0.23)",null,"0.08 (0.00,0.23)","0.00 (0.00,0.00)","0.08 (0.00,0.23)",5,"fnhome",0,0.1526153846,0.1546153846,0,0,0,0,0.1538461538,0.4615384615,0,0.1538461538,0.4615384615,0,0.0763076923,0.0773076923,0,0,0,0,0.0769230769,0.2307692308,0,0.0769230769,0.2307692308,0,0.0763076923,0.0773076923,0,0,0,0,0.0769230769,0.2307692308,0,0.0769230769,0.2307692308,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Other Care/No Action",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",6,"fnoth",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Unknown Care",{"$nulls":3},"0.15 (0.00,0.38)","0.00 (0.00,0.00)","0.15 (0.00,0.38)",null,"0.15 (0.00,0.38)","0.00 (0.00,0.00)","0.15 (0.00,0.38)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"fnunkn",0,0.1537692308,0.154,0,0,0,0,0.1538461538,0.3846153846,0,0.1538461538,0.3846153846,0,0.1537692308,0.154,0,0,0,0,0.1538461538,0.3846153846,0,0.1538461538,0.3846153846,0,0,0,0,0,0,0,0,0,0,0,0]
[null,"FN-Related Inpatient Care",{"$nulls":15},7,null,4.4723846154,4.3071538462,-0.156384615,3.5384615385,4.4615384615,5.3846153846,3.3076923077,4.3076923077,5.2307692308,-1.461538462,-0.153846154,1.0769230769,1,1,0,1,1,1,1,1,1,0,0,0,3.4723846154,3.3071538462,-0.156384615,2.5384615385,3.4615384615,4.3846153846,2.3076923077,3.3076923077,4.2307692308,-1.461538462,-0.153846154,1.0769230769]
[null,null,"Days in Hospital",{"$nulls":3},"4.31 (3.31,5.23)","4.47 (3.54,5.38)","-0.16 (-1.46,1.08)",null,"1.00 (1.00,1.00)","1.00 (1.00,1.00)","1.00 (1.00,1.00)",null,"3.31 (2.31,4.23)","3.47 (2.54,4.38)","-0.16 (-1.46,1.08)",8,"hospdays",4.4723846154,4.3071538462,-0.156384615,3.5384615385,4.4615384615,5.3846153846,3.3076923077,4.3076923077,5.2307692308,-1.461538462,-0.153846154,1.0769230769,1,1,0,1,1,1,1,1,1,0,0,0,3.4723846154,3.3071538462,-0.156384615,2.5384615385,3.4615384615,4.3846153846,2.3076923077,3.3076923077,4.2307692308,-1.461538462,-0.153846154,1.0769230769,null,4.4723846154,true,{"v":0,"d":"0.0000"}]
["Belgium (n=32)"]
[null,"No. of FN Events",{"$nulls":4},"1.41 (1.13,1.75)","0.12 (0.00,0.28)","1.28 (0.94,1.67)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.41 (0.13,0.75)","0.12 (0.00,0.28)","0.28 (-0.06,0.67)",2,"fnevent",0.12296875,1.4068125,1.282125,0,0.125,0.28125,1.125,1.40625,1.75,0.9375,1.28125,1.671875,0,1,1,0,0,0,1,1,1,1,1,1,0.12296875,0.4068125,0.282125,0,0.125,0.28125,0.125,0.40625,0.75,-0.0625,0.28125,0.671875]
[null,null,"Requiring Inpatient Care",{"$nulls":3},"1.22 (0.88,1.63)","0.12 (0.00,0.28)","1.09 (0.69,1.53)",null,"0.81 (0.67,0.94)","0.00 (0.00,0.00)","0.81 (0.66,0.94)",null,"0.41 (0.13,0.75)","0.12 (0.00,0.28)","0.28 (-0.06,0.67)",3,"fnhosp",0.12296875,1.2190625,1.09409375,0,0.125,0.28125,0.875,1.21875,1.625,0.6875,1.09375,1.53125,0,0.81225,0.81196875,0,0,0,0.671875,0.8125,0.9375,0.65625,0.8125,0.9375,0.12296875,0.4068125,0.282125,0,0.125,0.28125,0.125,0.40625,0.75,-0.0625,0.28125,0.671875,null,0.12296875,true,{"v":0,"d":"0.0000"},null,0.8665422719800968]
[null,null,"Requiring Outpatient Care",{"$nulls":3},"0.09 (0.00,0.20)","0.00 (0.00,0.00)","0.09 (0.00,0.22)",null,"0.09 (0.00,0.20)","0.00 (0.00,0.00)","0.09 (0.00,0.22)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",4,"fnout",0,0.09478125,0.0933125,0,0,0,0,0.09375,0.203125,0,0.09375,0.21875,0,0.09478125,0.0933125,0,0,0,0,0.09375,0.203125,0,0.09375,0.21875,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Home Care",{"$nulls":3},"0.06 (0.00,0.16)","0.00 (0.00,0.00)","0.06 (0.00,0.16)",null,"0.06 (0.00,0.16)","0.00 (0.00,0.00)","0.06 (0.00,0.16)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",5,"fnhome",0,0.0618125,0.063375,0,0,0,0,0.0625,0.15625,0,0.0625,0.15625,0,0.0618125,0.063375,0,0,0,0,0.0625,0.15625,0,0.0625,0.15625,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Other Care/No Action",{"$nulls":3},"0.03 (0.00,0.09)","0.00 (0.00,0.00)","0.03 (0.00,0.09)",null,"0.03 (0.00,0.09)","0.00 (0.00,0.00)","0.03 (0.00,0.09)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",6,"fnoth",0,0.03115625,0.03134375,0,0,0,0,0.03125,0.09375,0,0.03125,0.09375,0,0.03115625,0.03134375,0,0,0,0,0.03125,0.09375,0,0.03125,0.09375,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Unknown Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"fnunkn",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
[null,"FN-Related Inpatient Care",{"$nulls":15},7,null,5.0943125,5.15446875,0.0661875,4.34375,5.09375,5.765625,4.28125,5.15625,6.046875,-1.1875,0.0625,1.3125,1,1,0,1,1,1,1,1,1,0,0,0,4.0943125,4.15446875,0.0661875,3.34375,4.09375,4.765625,3.28125,4.15625,5.046875,-1.1875,0.0625,1.3125]
[null,null,"Days in Hospital",{"$nulls":3},"5.15 (4.28,6.05)","5.09 (4.34,5.77)","0.07 (-1.19,1.31)",null,"1.00 (1.00,1.00)","1.00 (1.00,1.00)","0.00 (0.00,0.00)",null,"4.15 (3.28,5.05)","4.09 (3.34,4.77)","0.07 (-1.19,1.31)",8,"hospdays",5.0943125,5.15446875,0.0661875,4.34375,5.09375,5.765625,4.28125,5.15625,6.046875,-1.1875,0.0625,1.3125,1,1,0,1,1,1,1,1,1,0,0,0,4.0943125,4.15446875,0.0661875,3.34375,4.09375,4.765625,3.28125,4.15625,5.046875,-1.1875,0.0625,1.3125,null,5.0943125,true,{"v":0,"d":"0.0000"}]
["France (n=62)"]
[null,"No. of FN Events",{"$nulls":4},"1.42 (1.24,1.65)","0.16 (0.05,0.31)","1.26 (1.03,1.50)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.42 (0.24,0.65)","0.16 (0.05,0.31)","0.26 (0.03,0.50)",2,"fnevent",0.1619193548,1.420516129,1.2587258065,0.0483870968,0.1612903226,0.314516129,1.2419354839,1.4193548387,1.6451612903,1.0322580645,1.2580645161,1.5,0,1,1,0,0,0,1,1,1,1,1,1,0.1619193548,0.420516129,0.2587258065,0.0483870968,0.1612903226,0.314516129,0.2419354839,0.4193548387,0.6451612903,0.0322580645,0.2580645161,0.5]
[null,null,"Requiring Inpatient Care",{"$nulls":3},"0.90 (0.69,1.12)","0.11 (0.03,0.23)","0.79 (0.53,1.02)",null,"0.61 (0.48,0.73)","0.00 (0.00,0.00)","0.61 (0.48,0.73)",null,"0.29 (0.15,0.47)","0.11 (0.03,0.23)","0.18 (0.00,0.35)",3,"fnhosp",0.1132419355,0.9005645161,0.7886451613,0.0322580645,0.1129032258,0.2258064516,0.685483871,0.9032258065,1.1209677419,0.5322580645,0.7903225806,1.0161290323,0,0.6111129032,0.6114677419,0,0,0,0.4838709677,0.6129032258,0.7258064516,0.4838709677,0.6129032258,0.7258064516,0.1132419355,0.2894516129,0.1771774194,0.0322580645,0.1129032258,0.2258064516,0.1451612903,0.2903225806,0.4677419355,0,0.1774193548,0.3548387097,null,0.1132419355,true,{"v":0,"d":"0.0000"},null,0.6339699336845757]
[null,null,"Requiring Outpatient Care",{"$nulls":3},"0.08 (0.02,0.16)","0.03 (0.00,0.08)","0.05 (-0.03,0.13)",null,"0.06 (0.02,0.13)","0.00 (0.00,0.00)","0.06 (0.02,0.13)",null,"0.02 (0.00,0.05)","0.03 (0.00,0.08)","-0.02 (-0.06,0.03)",4,"fnout",0.0322258065,0.0800483871,0.0477258065,0,0.0322580645,0.0806451613,0.0161290323,0.0806451613,0.1612903226,-0.032258065,0.0483870968,0.1290322581,0,0.0642903226,0.0641612903,0,0,0,0.0161290323,0.064516129,0.1290322581,0.0161290323,0.064516129,0.1290322581,0.0322258065,0.0157580645,-0.016435484,0,0.0322580645,0.0806451613,0,0.0161290323,0.0483870968,-0.064516129,-0.016129032,0.0322580645,null,0.0322258065,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Home Care",{"$nulls":3},"0.36 (0.18,0.55)","0.02 (0.00,0.05)","0.34 (0.17,0.56)",null,"0.26 (0.16,0.37)","0.00 (0.00,0.00)","0.26 (0.16,0.37)",null,"0.10 (0.00,0.24)","0.02 (0.00,0.05)","0.08 (-0.03,0.25)",5,"fnhome",0.0164516129,0.3592741935,0.3412258065,0,0.0161290323,0.0483870968,0.1774193548,0.3548387097,0.5483870968,0.1693548387,0.3387096774,0.564516129,0,0.2604354839,0.2593548387,0,0,0,0.1612903226,0.2580645161,0.3709677419,0.1612903226,0.2580645161,0.3709677419,0.0164516129,0.0988387097,0.0818709677,0,0.0161290323,0.0483870968,0,0.0967741935,0.2419354839,-0.032258065,0.0806451613,0.25,null,0.0164516129,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Other Care/No Action",{"$nulls":3},"0.03 (0.00,0.08)","0.00 (0.00,0.00)","0.03 (0.00,0.08)",null,"0.02 (0.00,0.06)","0.00 (0.00,0.00)","0.02 (0.00,0.05)",null,"0.02 (0.00,0.05)","0.00 (0.00,0.00)","0.02 (0.00,0.05)",6,"fnoth",0,0.0328387097,0.0323548387,0,0,0,0,0.0322580645,0.0806451613,0,0.0322580645,0.0806451613,0,0.0163709677,0.0162419355,0,0,0,0,0.0161290323,0.064516129,0,0.0161290323,0.0483870968,0,0.0164677419,0.0161129032,0,0,0,0,0.0161290323,0.0483870968,0,0.0161290323,0.0483870968,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Unknown Care",{"$nulls":3},"0.05 (0.00,0.11)","0.00 (0.00,0.00)","0.05 (0.00,0.11)",null,"0.05 (0.00,0.11)","0.00 (0.00,0.00)","0.05 (0.00,0.11)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"fnunkn",0,0.0477903226,0.0487741935,0,0,0,0,0.0483870968,0.1129032258,0,0.0483870968,0.1129032258,0,0.0477903226,0.0487741935,0,0,0,0,0.0483870968,0.1129032258,0,0.0483870968,0.1129032258,0,0,0,0,0,0,0,0,0,0,0,0]
[null,"FN-Related Inpatient Care",{"$nulls":15},7,null,5.229016129,5.2074193548,-0.012064516,4.6612903226,5.2258064516,5.7580645161,4.7096774194,5.2096774194,5.685483871,-0.741935484,0,0.7177419355,1,1,0,1,1,1,1,1,1,0,0,0,4.229016129,4.2074193548,-0.012064516,3.6612903226,4.2258064516,4.7580645161,3.7096774194,4.2096774194,4.685483871,-0.741935484,0,0.7177419355]
[null,null,"Days in Hospital",{"$nulls":3},"5.21 (4.71,5.69)","5.23 (4.66,5.76)","-0.01 (-0.74,0.72)",null,"1.00 (1.00,1.00)","1.00 (1.00,1.00)","1.00 (1.00,1.00)",null,"4.21 (3.71,4.69)","4.23 (3.66,4.76)","-0.01 (-0.74,0.72)",8,"hospdays",5.229016129,5.2074193548,-0.012064516,4.6612903226,5.2258064516,5.7580645161,4.7096774194,5.2096774194,5.685483871,-0.741935484,0,0.7177419355,1,1,0,1,1,1,1,1,1,0,0,0,4.229016129,4.2074193548,-0.012064516,3.6612903226,4.2258064516,4.7580645161,3.7096774194,4.2096774194,4.685483871,-0.741935484,0,0.7177419355,null,5.229016129,true,{"v":0,"d":"0.0000"}]
[]
["Online Supplement -- Table S5 (cont).  Healthcare utilization among FN patients and matched comparison patients matched, by country"]
[]
[{"$nulls":6},"Mean (95% CI)"]
[]
[{"$nulls":6},"Overall*",{"$nulls":3},"Index Cycle",{"$nulls":3},"Post-Index Cycles"]
[]
[{"$nulls":6},"FN","Comparison",null,null,"FN","Comparison",null,null,"FN","Comparison"]
["Healthcare Resources",{"$nulls":5},"Patients","Patients","Difference",null,"Patients","Patients","Difference",null,"Patients","Patients","Difference","rown","varname","stat1","stat12_5","stat197_5","stat2",null,"stat22_5","stat297_5",{"$nulls":5},"stat3","stat32_5","stat397_5","stat4",null,"stat42_5","stat497_5",{"$nulls":5},"stat5","stat52_5","stat597_5","stat6",null,"stat62_5","stat697_5"]
["Germany (n=24)"]
[null,"No. of FN Events",{"$nulls":4},"1.46 (1.13,1.88)","0.04 (0.00,0.13)","1.41 (1.02,1.88)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.46 (0.13,0.88)","0.04 (0.00,0.13)","0.41 (0.02,0.88)",2,"fnevent",0.0419166667,1.45725,1.4119583333,0,0.0416666667,0.125,1.125,1.4166666667,1.875,1.0208333333,1.4166666667,1.875,0,1,1,0,0,0,1,1,1,1,1,1,0.0419166667,0.45725,0.4119583333,0,0.0416666667,0.125,0.125,0.4166666667,0.875,0.0208333333,0.4166666667,0.875]
[null,null,"Requiring Inpatient Care",{"$nulls":3},"0.79 (0.42,1.29)","0.04 (0.00,0.13)","0.75 (0.38,1.29)",null,"0.54 (0.33,0.71)","0.00 (0.00,0.00)","0.54 (0.33,0.75)",null,"0.25 (0.00,0.63)","0.04 (0.00,0.13)","0.21 (-0.08,0.63)",3,"fnhosp",0.0419166667,0.7900833333,0.7478333333,0,0.0416666667,0.125,0.4166666667,0.7916666667,1.2916666667,0.375,0.7083333333,1.2916666667,0,0.540875,0.5416666667,0,0,0,0.3333333333,0.5416666667,0.7083333333,0.3333333333,0.5416666667,0.75,0.0419166667,0.2492083333,0.2061666667,0,0.0416666667,0.125,0,0.2083333333,0.625,-0.083333333,0.2083333333,0.625,null,0.0419166667,true,{"v":0,"d":"0.0000"},null,0.5421741865156974]
[null,null,"Requiring Outpatient Care",{"$nulls":3},"0.12 (0.00,0.25)","0.00 (0.00,0.00)","0.12 (0.00,0.25)",null,"0.08 (0.00,0.21)","0.00 (0.00,0.00)","0.08 (0.00,0.21)",null,"0.04 (0.00,0.13)","0.00 (0.00,0.00)","0.04 (0.00,0.13)",4,"fnout",0,0.1236666667,0.1238333333,0,0,0,0,0.125,0.25,0,0.125,0.25,0,0.083,0.08375,0,0,0,0,0.0833333333,0.2083333333,0,0.0833333333,0.2083333333,0,0.0406666667,0.0400833333,0,0,0,0,0.0416666667,0.125,0,0.0416666667,0.125,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Home Care",{"$nulls":3},"0.12 (0.00,0.29)","0.00 (0.00,0.00)","0.12 (0.00,0.33)",null,"0.08 (0.00,0.21)","0.00 (0.00,0.00)","0.08 (0.00,0.21)",null,"0.04 (0.00,0.13)","0.00 (0.00,0.00)","0.04 (0.00,0.13)",5,"fnhome",0,0.1234583333,0.121375,0,0,0,0,0.125,0.2916666667,0,0.125,0.3333333333,0,0.0827916667,0.0812916667,0,0,0,0,0.0833333333,0.2083333333,0,0.0833333333,0.2083333333,0,0.0406666667,0.0400833333,0,0,0,0,0.0416666667,0.125,0,0.0416666667,0.125,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Other Care/No Action",{"$nulls":3},"0.21 (0.08,0.38)","0.00 (0.00,0.00)","0.21 (0.04,0.38)",null,"0.21 (0.08,0.38)","0.00 (0.00,0.00)","0.21 (0.04,0.38)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",6,"fnoth",0,0.2095833333,0.2092916667,0,0,0,0.0833333333,0.2083333333,0.375,0.0416666667,0.2083333333,0.375,0,0.2095833333,0.2092916667,0,0,0,0.0833333333,0.2083333333,0.375,0.0416666667,0.2083333333,0.375,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Unknown Care",{"$nulls":3},"0.21 (0.00,0.50)","0.00 (0.00,0.00)","0.21 (0.00,0.46)",null,"0.08 (0.00,0.21)","0.00 (0.00,0.00)","0.08 (0.00,0.21)",null,"0.13 (0.00,0.33)","0.00 (0.00,0.00)","0.13 (0.00,0.33)",null,"fnunkn",0,0.2104583333,0.209625,0,0,0,0,0.2083333333,0.5,0,0.2083333333,0.4583333333,0,0.08375,0.084,0,0,0,0,0.0833333333,0.2083333333,0,0.0833333333,0.2083333333,0,0.1267083333,0.125625,0,0,0,0,0.125,0.3333333333,0,0.125,0.3333333333]
[null,"FN-Related Inpatient Care",{"$nulls":15},7,null,4.0461666667,3.7956666667,-0.246208333,3.3125,4.0416666667,4.75,3.0416666667,3.7916666667,4.5416666667,-1.291666667,-0.25,0.875,1,1,0,1,1,1,1,1,1,0,0,0,3.0461666667,2.7956666667,-0.246208333,2.3125,3.0416666667,3.75,2.0416666667,2.7916666667,3.5416666667,-1.291666667,-0.25,0.875]
[null,null,"Days in Hospital",{"$nulls":3},"3.80 (3.04,4.54)","4.05 (3.31,4.75)","-0.25 (-1.29,0.88)",null,"1.00 (1.00,1.00)","1.00 (1.00,1.00)","0.00 (0.00,0.00)",null,"2.80 (2.04,3.54)","3.05 (2.31,3.75)","-0.25 (-1.29,0.88)",8,"hospdays",4.0461666667,3.7956666667,-0.246208333,3.3125,4.0416666667,4.75,3.0416666667,3.7916666667,4.5416666667,-1.291666667,-0.25,0.875,1,1,0,1,1,1,1,1,1,0,0,0,3.0461666667,2.7956666667,-0.246208333,2.3125,3.0416666667,3.75,2.0416666667,2.7916666667,3.5416666667,-1.291666667,-0.25,0.875,null,4.0461666667,true,{"v":0,"d":"0.0000"}]
["Greece (n=5)"]
[null,"No. of FN Events",{"$nulls":4},"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",2,"fnevent",0,1,1,0,0,0,1,1,1,1,1,1,0,1,1,0,0,0,1,1,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0]
[null,null,"Requiring Inpatient Care",{"$nulls":3},"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",3,"fnhosp",0,1,1,0,0,0,1,1,1,1,1,1,0,1,1,0,0,0,1,1,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Outpatient Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",4,"fnout",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Home Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",5,"fnhome",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Other Care/No Action",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",6,"fnoth",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Unknown Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"fnunkn",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
[null,"FN-Related Inpatient Care",{"$nulls":17},3.3996,3.3952,-0.0132,1.8,3.4,5,1.6,3.4,5.8,-3.2,0,3.2,1,1,0,1,1,1,1,1,1,0,0,0,2.3996,2.3952,-0.0132,0.8,2.4,4,0.6,2.4,4.8,-3.2,0,3.2]
[null,null,"Days in Hospital",{"$nulls":3},"3.40 (1.60,5.80)","3.40 (1.80,5.00)","-0.01 (-3.20,3.20)",null,"1.00 (1.00,1.00)","1.00 (1.00,1.00)","1.00 (1.00,1.00)",null,"2.40 (0.60,4.80)","2.40 (0.80,4.00)","-0.01 (-3.20,3.20)",8,"hospdays",3.3996,3.3952,-0.0132,1.8,3.4,5,1.6,3.4,5.8,-3.2,0,3.2,1,1,0,1,1,1,1,1,1,0,0,0,2.3996,2.3952,-0.0132,0.8,2.4,4,0.6,2.4,4.8,-3.2,0,3.2,null,3.3996,true,{"v":0,"d":"0.0000"}]
["Italy (n=12)"]
[null,"No. of FN Events",{"$nulls":4},"1.08 (1.00,1.25)","0.17 (0.00,0.42)","0.92 (0.67,1.17)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.08 (0.00,0.25)","0.17 (0.00,0.42)","-0.08 (-0.33,0.17)",2,"fnevent",0.1671666667,1.0839166667,0.9166666667,0,0.1666666667,0.4166666667,1,1.0833333333,1.25,0.6666666667,0.9166666667,1.1666666667,0,1,1,0,0,0,1,1,1,1,1,1,0.1671666667,0.0839166667,-0.083333333,0,0.1666666667,0.4166666667,0,0.0833333333,0.25,-0.333333333,-0.083333333,0.1666666667]
[null,null,"Requiring Inpatient Care",{"$nulls":3},"0.33 (0.08,0.58)","0.08 (0.00,0.25)","0.25 (-0.08,0.58)",null,"0.33 (0.08,0.58)","0.00 (0.00,0.00)","0.33 (0.08,0.58)",null,"0.00 (0.00,0.00)","0.08 (0.00,0.25)","-0.08 (-0.25,0.00)",3,"fnhosp",0.0828333333,0.3334166667,0.2515,0,0.0833333333,0.25,0.0833333333,0.3333333333,0.5833333333,-0.083333333,0.25,0.5833333333,0,0.3334166667,0.3345,0,0,0,0.0833333333,0.3333333333,0.5833333333,0.0833333333,0.3333333333,0.5833333333,0.0828333333,0,-0.083,0,0.0833333333,0.25,0,0,0,-0.25,-0.083333333,0,null,0.0828333333,true,{"v":0,"d":"0.0000"},null,0.3076035980838747]
[null,null,"Requiring Outpatient Care",{"$nulls":3},"0.17 (0.00,0.42)","0.08 (0.00,0.25)","0.08 (-0.17,0.33)",null,"0.17 (0.00,0.42)","0.00 (0.00,0.00)","0.17 (0.00,0.42)",null,"0.00 (0.00,0.00)","0.08 (0.00,0.25)","-0.08 (-0.25,0.00)",4,"fnout",0.0843333333,0.1664166667,0.0826666667,0,0.0833333333,0.25,0,0.1666666667,0.4166666667,-0.166666667,0.0833333333,0.3333333333,0,0.1664166667,0.1663333333,0,0,0,0,0.1666666667,0.4166666667,0,0.1666666667,0.4166666667,0.0843333333,0,-0.083666667,0,0.0833333333,0.25,0,0,0,-0.25,-0.083333333,0,null,0.0843333333,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Home Care",{"$nulls":3},"0.58 (0.33,0.83)","0.00 (0.00,0.00)","0.58 (0.33,0.83)",null,"0.50 (0.25,0.83)","0.00 (0.00,0.00)","0.50 (0.25,0.75)",null,"0.08 (0.00,0.25)","0.00 (0.00,0.00)","0.08 (0.00,0.25)",5,"fnhome",0,0.5840833333,0.5825,0,0,0,0.3333333333,0.5833333333,0.8333333333,0.3333333333,0.5833333333,0.8333333333,0,0.5001666667,0.4991666667,0,0,0,0.25,0.5,0.8333333333,0.25,0.5,0.75,0,0.0839166667,0.0833333333,0,0,0,0,0.0833333333,0.25,0,0.0833333333,0.25,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Other Care/No Action",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",6,"fnoth",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Unknown Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"fnunkn",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
[null,"FN-Related Inpatient Care",{"$nulls":15},7,null,4.24175,4.1675833333,-0.084416667,3.4166666667,4.25,5,3.3333333333,4.1666666667,4.9166666667,-1.166666667,-0.083333333,1.0833333333,1,1,0,1,1,1,1,1,1,0,0,0,3.24175,3.1675833333,-0.084416667,2.4166666667,3.25,4,2.3333333333,3.1666666667,3.9166666667,-1.166666667,-0.083333333,1.0833333333]
[null,null,"Days in Hospital",{"$nulls":3},"4.17 (3.33,4.92)","4.24 (3.42,5.00)","-0.08 (-1.17,1.08)",null,"1.00 (1.00,1.00)","1.00 (1.00,1.00)","1.00 (1.00,1.00)",null,"3.17 (2.33,3.92)","3.24 (2.42,4.00)","-0.08 (-1.17,1.08)",8,"hospdays",4.24175,4.1675833333,-0.084416667,3.4166666667,4.25,5,3.3333333333,4.1666666667,4.9166666667,-1.166666667,-0.083333333,1.0833333333,1,1,0,1,1,1,1,1,1,0,0,0,3.24175,3.1675833333,-0.084416667,2.4166666667,3.25,4,2.3333333333,3.1666666667,3.9166666667,-1.166666667,-0.083333333,1.0833333333,null,4.24175,true,{"v":0,"d":"0.0000"}]
[]
["Online Supplement -- Table S5 (cont).  Healthcare utilization among FN patients and matched comparison patients matched, by country"]
[]
[{"$nulls":6},"Mean (95% CI)"]
[]
[{"$nulls":6},"Overall*",{"$nulls":3},"Index Cycle",{"$nulls":3},"Post-Index Cycles"]
[]
[{"$nulls":6},"FN","Comparison",null,null,"FN","Comparison",null,null,"FN","Comparison"]
["Healthcare Resources",{"$nulls":5},"Patients","Patients","Difference",null,"Patients","Patients","Difference",null,"Patients","Patients","Difference","rown","varname","stat1","stat12_5","stat197_5","stat2",null,"stat22_5","stat297_5",{"$nulls":5},"stat3","stat32_5","stat397_5","stat4",null,"stat42_5","stat497_5",{"$nulls":5},"stat5","stat52_5","stat597_5","stat6",null,"stat62_5","stat697_5"]
["Netherlands (n=22)"]
[null,"No. of FN Events",{"$nulls":4},"1.46 (1.14,1.82)","0.32 (0.00,0.89)","1.14 (0.73,1.55)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.46 (0.14,0.82)","0.32 (0.00,0.89)","0.14 (-0.27,0.55)",2,"fnevent",0.3190909091,1.4560909091,1.1375454545,0,0.3181818182,0.8863636364,1.1363636364,1.4545454545,1.8181818182,0.7272727273,1.1363636364,1.5454545455,0,1,1,0,0,0,1,1,1,1,1,1,0.3190909091,0.4560909091,0.1375454545,0,0.3181818182,0.8863636364,0.1363636364,0.4545454545,0.8181818182,-0.272727273,0.1363636364,0.5454545455]
[null,null,"Requiring Inpatient Care",{"$nulls":3},"1.32 (1.00,1.68)","0.00 (0.00,0.00)","1.32 (1.00,1.73)",null,"0.86 (0.73,1.00)","0.00 (0.00,0.00)","0.86 (0.68,1.00)",null,"0.46 (0.14,0.82)","0.00 (0.00,0.00)","0.46 (0.14,0.86)",3,"fnhosp",0,1.3201363636,1.3206818182,0,0,0,1,1.3181818182,1.6818181818,1,1.3181818182,1.7272727273,0,0.8640454545,0.8625454545,0,0,0,0.7272727273,0.8636363636,1,0.6818181818,0.8636363636,1,0,0.4560909091,0.4581363636,0,0,0,0.1363636364,0.4545454545,0.8181818182,0.1363636364,0.4545454545,0.8636363636,null,0,true,{"v":0,"d":"0.0000"},null,0.9066304551107783]
[null,null,"Requiring Outpatient Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",4,"fnout",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Home Care",{"$nulls":3},"0.09 (0.00,0.23)","0.32 (0.00,0.89)","-0.23 (-0.91,0.18)",null,"0.09 (0.00,0.23)","0.00 (0.00,0.00)","0.09 (0.00,0.23)",null,"0.00 (0.00,0.00)","0.32 (0.00,0.89)","-0.32 (-0.95,0.00)",5,"fnhome",0.3190909091,0.0909090909,-0.228318182,0,0.3181818182,0.8863636364,0,0.0909090909,0.2272727273,-0.909090909,-0.181818182,0.1818181818,0,0.0909090909,0.0922727273,0,0,0,0,0.0909090909,0.2272727273,0,0.0909090909,0.2272727273,0.3190909091,0,-0.320590909,0,0.3181818182,0.8863636364,0,0,0,-0.954545455,-0.318181818,0,null,0.3190909091,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Other Care/No Action",{"$nulls":3},"0.05 (0.00,0.14)","0.00 (0.00,0.00)","0.05 (0.00,0.14)",null,"0.05 (0.00,0.14)","0.00 (0.00,0.00)","0.05 (0.00,0.14)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",6,"fnoth",0,0.0450454545,0.0451818182,0,0,0,0,0.0454545455,0.1363636364,0,0.0454545455,0.1363636364,0,0.0450454545,0.0451818182,0,0,0,0,0.0454545455,0.1363636364,0,0.0454545455,0.1363636364,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Unknown Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"fnunkn",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
[null,"FN-Related Inpatient Care",{"$nulls":15},7,null,3.9033181818,4.6815,0.7828636364,3.0454545455,3.9090909091,4.7727272727,3.6818181818,4.6818181818,5.7045454545,-0.545454545,0.7727272727,2.1590909091,1,1,0,1,1,1,1,1,1,0,0,0,2.9033181818,3.6815,0.7828636364,2.0454545455,2.9090909091,3.7727272727,2.6818181818,3.6818181818,4.7045454545,-0.545454545,0.7727272727,2.1590909091]
[null,null,"Days in Hospital",{"$nulls":3},"4.68 (3.68,5.70)","3.90 (3.05,4.77)","0.78 (-0.55,2.16)",null,"1.00 (1.00,1.00)","1.00 (1.00,1.00)","1.00 (1.00,1.00)",null,"3.68 (2.68,4.70)","2.90 (2.05,3.77)","0.78 (-0.55,2.16)",8,"hospdays",3.9033181818,4.6815,0.7828636364,3.0454545455,3.9090909091,4.7727272727,3.6818181818,4.6818181818,5.7045454545,-0.545454545,0.7727272727,2.1590909091,1,1,0,1,1,1,1,1,1,0,0,0,2.9033181818,3.6815,0.7828636364,2.0454545455,2.9090909091,3.7727272727,2.6818181818,3.6818181818,4.7045454545,-0.545454545,0.7727272727,2.1590909091,null,3.9033181818,true,{"v":0,"d":"0.0000"}]
["Nordics (n=16)"]
[null,"No. of FN Events",{"$nulls":4},"1.63 (1.25,2.06)","0.37 (0.06,0.75)","1.25 (0.75,1.81)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.63 (0.25,1.06)","0.37 (0.06,0.75)","0.25 (-0.25,0.81)",2,"fnevent",0.3724375,1.628375,1.2519375,0.0625,0.375,0.75,1.25,1.625,2.0625,0.75,1.25,1.8125,0,1,1,0,0,0,1,1,1,1,1,1,0.3724375,0.628375,0.2519375,0.0625,0.375,0.75,0.25,0.625,1.0625,-0.25,0.25,0.8125]
[null,null,"Requiring Inpatient Care",{"$nulls":3},"1.50 (1.06,1.94)","0.37 (0.06,0.75)","1.13 (0.56,1.75)",null,"0.94 (0.81,1.00)","0.00 (0.00,0.00)","0.94 (0.81,1.00)",null,"0.57 (0.19,1.00)","0.37 (0.06,0.75)","0.19 (-0.31,0.75)",3,"fnhosp",0.3724375,1.5033125,1.1276875,0.0625,0.375,0.75,1.0625,1.5,1.9375,0.5625,1.125,1.75,0,0.93725,0.93825,0,0,0,0.8125,0.9375,1,0.8125,0.9375,1,0.3724375,0.5660625,0.1894375,0.0625,0.375,0.75,0.1875,0.5625,1,-0.3125,0.1875,0.75,null,0.3724375,true,{"v":0,"d":"0.0000"},null,0.923197973439779]
[null,null,"Requiring Outpatient Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",4,"fnout",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Home Care",{"$nulls":3},"0.06 (0.00,0.19)","0.00 (0.00,0.00)","0.06 (0.00,0.19)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.06 (0.00,0.19)","0.00 (0.00,0.00)","0.06 (0.00,0.19)",5,"fnhome",0,0.0623125,0.0625,0,0,0,0,0.0625,0.1875,0,0.0625,0.1875,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0623125,0.0625,0,0,0,0,0.0625,0.1875,0,0.0625,0.1875,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Other Care/No Action",{"$nulls":3},"0.06 (0.00,0.19)","0.00 (0.00,0.00)","0.06 (0.00,0.19)",null,"0.06 (0.00,0.19)","0.00 (0.00,0.00)","0.06 (0.00,0.19)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",6,"fnoth",0,0.06275,0.06175,0,0,0,0,0.0625,0.1875,0,0.0625,0.1875,0,0.06275,0.06175,0,0,0,0,0.0625,0.1875,0,0.0625,0.1875,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Unknown Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"fnunkn",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
[null,"FN-Related Inpatient Care",{"$nulls":15},7,null,4.5026875,4.37675,-0.1001875,3.6875,4.5,5.375,3.28125,4.375,5.4375,-1.6875,-0.125,1.3125,1,1,0,1,1,1,1,1,1,0,0,0,3.5026875,3.37675,-0.1001875,2.6875,3.5,4.375,2.28125,3.375,4.4375,-1.6875,-0.125,1.3125]
[null,null,"Days in Hospital",{"$nulls":3},"4.38 (3.28,5.44)","4.50 (3.69,5.38)","-0.10 (-1.69,1.31)",null,"1.00 (1.00,1.00)","1.00 (1.00,1.00)","1.00 (1.00,1.00)",null,"3.38 (2.28,4.44)","3.50 (2.69,4.38)","-0.10 (-1.69,1.31)",8,"hospdays",4.5026875,4.37675,-0.1001875,3.6875,4.5,5.375,3.28125,4.375,5.4375,-1.6875,-0.125,1.3125,1,1,0,1,1,1,1,1,1,0,0,0,3.5026875,3.37675,-0.1001875,2.6875,3.5,4.375,2.28125,3.375,4.4375,-1.6875,-0.125,1.3125,null,4.5026875,true,{"v":0,"d":"0.0000"}]
["Portugal (n=3)"]
[null,"No. of FN Events",{"$nulls":4},"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",2,"fnevent",0,1,1,0,0,0,1,1,1,1,1,1,0,1,1,0,0,0,1,1,1,1,1,1,0,0,0,0,0,0,0,0,0,0,0,0]
[null,null,"Requiring Inpatient Care",{"$nulls":3},"0.67 (0.00,1.00)","0.00 (0.00,0.00)","0.67 (0.00,1.00)",null,"0.67 (0.00,1.00)","0.00 (0.00,0.00)","0.67 (0.00,1.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",3,"fnhosp",0,0.6656666667,0.669,0,0,0,0,0.6666666667,1,0,0.6666666667,1,0,0.6656666667,0.669,0,0,0,0,0.6666666667,1,0,0.6666666667,1,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Outpatient Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",4,"fnout",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Home Care",{"$nulls":3},"0.33 (0.00,1.00)","0.00 (0.00,0.00)","0.33 (0.00,1.00)",null,"0.33 (0.00,1.00)","0.00 (0.00,0.00)","0.33 (0.00,1.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",5,"fnhome",0,0.3343333333,0.331,0,0,0,0,0.3333333333,1,0,0.3333333333,1,0,0.3343333333,0.331,0,0,0,0,0.3333333333,1,0,0.3333333333,1,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Other Care/No Action",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",6,"fnoth",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Unknown Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"fnunkn",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
[null,"FN-Related Inpatient Care",{"$nulls":15},7,null,6.6813333333,3.6746666667,-2.99,4,6.6666666667,8,1,3.6666666667,8,-6,-3,0,1,1,0,1,1,1,1,1,1,0,0,0,5.6813333333,2.6746666667,-2.99,3,5.6666666667,7,0,2.6666666667,7,-6,-3,0]
[null,null,"Days in Hospital",{"$nulls":3},"3.67 (1.00,8.00)","6.68 (4.00,8.00)","-2.99 (-6.00,0.00)",null,"1.00 (1.00,1.00)","1.00 (1.00,1.00)","1.00 (1.00,1.00)",null,"2.67 (0.00,7.00)","5.68 (3.00,7.00)","-2.99 (-6.00,0.00)",8,"hospdays",6.6813333333,3.6746666667,-2.99,4,6.6666666667,8,1,3.6666666667,8,-6,-3,0,1,1,0,1,1,1,1,1,1,0,0,0,5.6813333333,2.6746666667,-2.99,3,5.6666666667,7,0,2.6666666667,7,-6,-3,0,null,6.6813333333,true,{"v":0,"d":"0.0000"}]
["Spain (n=30)"]
[null,"No. of FN Events",{"$nulls":4},"1.46 (1.17,1.80)","0.23 (0.07,0.43)","1.23 (0.80,1.67)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.46 (0.17,0.80)","0.23 (0.07,0.43)","0.23 (-0.20,0.67)",2,"fnevent",0.2302333333,1.4562,1.2314666667,0.0666666667,0.2333333333,0.4333333333,1.1666666667,1.4333333333,1.8,0.8,1.2333333333,1.6666666667,0,1,1,0,0,0,1,1,1,1,1,1,0.2302333333,0.4562,0.2314666667,0.0666666667,0.2333333333,0.4333333333,0.1666666667,0.4333333333,0.8,-0.2,0.2333333333,0.6666666667]
[null,null,"Requiring Inpatient Care",{"$nulls":3},"1.46 (1.17,1.80)","0.17 (0.03,0.35)","1.30 (0.90,1.73)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.46 (0.17,0.80)","0.17 (0.03,0.35)","0.30 (-0.10,0.73)",3,"fnhosp",0.1654333333,1.4562,1.2989333333,0.0333333333,0.1666666667,0.35,1.1666666667,1.4333333333,1.8,0.9,1.3,1.7333333333,0,1,1,0,0,0,1,1,1,1,1,1,0.1654333333,0.4562,0.2989333333,0.0333333333,0.1666666667,0.35,0.1666666667,0.4333333333,0.8,-0.1,0.3,0.7333333333,null,0.1654333333,true,{"v":0,"d":"0.0000"},null,1]
[null,null,"Requiring Outpatient Care",{"$nulls":3},"0.00 (0.00,0.00)","0.06 (0.00,0.20)","-0.07 (-0.20,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.06 (0.00,0.20)","-0.07 (-0.20,0.00)",4,"fnout",0.0648,0,-0.067466667,0,0.0666666667,0.2,0,0,0,-0.2,-0.066666667,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0648,0,-0.067466667,0,0.0666666667,0.2,0,0,0,-0.2,-0.066666667,0,null,0.0648,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Home Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",5,"fnhome",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Other Care/No Action",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",6,"fnoth",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Unknown Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"fnunkn",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
[null,"FN-Related Inpatient Care",{"$nulls":15},7,null,5.4283333333,4.3624333333,-1.0789,4.75,5.4333333333,6.0666666667,3.7333333333,4.3666666667,5.0666666667,-2.1,-1.066666667,-0.1,1,1,0,1,1,1,1,1,1,0,0,0,4.4283333333,3.3624333333,-1.0789,3.75,4.4333333333,5.0666666667,2.7333333333,3.3666666667,4.0666666667,-2.1,-1.066666667,-0.1]
[null,null,"Days in Hospital",{"$nulls":3},"4.36 (3.73,5.07)","5.43 (4.75,6.07)","-1.08 (-2.10,-0.10)",null,"1.00 (1.00,1.00)","1.00 (1.00,1.00)","1.00 (1.00,1.00)",null,"3.36 (2.73,4.07)","4.43 (3.75,5.07)","-1.08 (-2.10,-0.10)",8,"hospdays",5.4283333333,4.3624333333,-1.0789,4.75,5.4333333333,6.0666666667,3.7333333333,4.3666666667,5.0666666667,-2.1,-1.066666667,-0.1,1,1,0,1,1,1,1,1,1,0,0,0,4.4283333333,3.3624333333,-1.0789,3.75,4.4333333333,5.0666666667,2.7333333333,3.3666666667,4.0666666667,-2.1,-1.066666667,-0.1,null,5.4283333333,true,{"v":0,"d":"0.0000"}]
[]
["Online Supplement -- Table S5 (cont).  Healthcare utilization among FN patients and matched comparison patients matched, by country"]
[]
[{"$nulls":6},"Mean (95% CI)"]
[]
[{"$nulls":6},"Overall*",{"$nulls":3},"Index Cycle",{"$nulls":3},"Post-Index Cycles"]
[]
[{"$nulls":6},"FN","Comparison",null,null,"FN","Comparison",null,null,"FN","Comparison"]
["Healthcare Resources",{"$nulls":5},"Patients","Patients","Difference",null,"Patients","Patients","Difference",null,"Patients","Patients","Difference","rown","varname","stat1","stat12_5","stat197_5","stat2",null,"stat22_5","stat297_5",{"$nulls":5},"stat3","stat32_5","stat397_5","stat4",null,"stat42_5","stat497_5",{"$nulls":5},"stat5","stat52_5","stat597_5","stat6",null,"stat62_5","stat697_5"]
["Switzerland (n=3)"]
[null,"No. of FN Events",{"$nulls":4},"1.33 (1.00,2.00)","0.00 (0.00,0.00)","1.33 (1.00,2.00)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.33 (0.00,1.00)","0.00 (0.00,0.00)","0.33 (0.00,1.00)",2,"fnevent",0,1.3343333333,1.3343333333,0,0,0,1,1.3333333333,2,1,1.3333333333,2,0,1,1,0,0,0,1,1,1,1,1,1,0,0.3343333333,0.3343333333,0,0,0,0,0.3333333333,1,0,0.3333333333,1]
[null,null,"Requiring Inpatient Care",{"$nulls":3},"0.67 (0.00,2.00)","0.00 (0.00,0.00)","0.67 (0.00,2.00)",null,"0.33 (0.00,1.00)","0.00 (0.00,0.00)","0.33 (0.00,1.00)",null,"0.33 (0.00,1.00)","0.00 (0.00,0.00)","0.33 (0.00,1.00)",3,"fnhosp",0,0.6686666667,0.6686666667,0,0,0,0,0.6666666667,2,0,0.6666666667,2,0,0.3343333333,0.3343333333,0,0,0,0,0.3333333333,1,0,0.3333333333,1,0,0.3343333333,0.3343333333,0,0,0,0,0.3333333333,1,0,0.3333333333,1,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Outpatient Care",{"$nulls":3},"0.67 (0.00,1.00)","0.00 (0.00,0.00)","0.67 (0.00,1.00)",null,"0.67 (0.00,1.00)","0.00 (0.00,0.00)","0.67 (0.00,1.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",4,"fnout",0,0.6656666667,0.6656666667,0,0,0,0,0.6666666667,1,0,0.6666666667,1,0,0.6656666667,0.6656666667,0,0,0,0,0.6666666667,1,0,0.6666666667,1,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Home Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",5,"fnhome",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Other Care/No Action",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",6,"fnoth",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Unknown Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"fnunkn",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
[null,"FN-Related Inpatient Care",{"$nulls":15},7,null,3.3196666667,4,0.6683333333,2,3.3333333333,5,2,4,6,-1,0.6666666667,3,1,1,0,1,1,1,1,1,1,0,0,0,2.3196666667,3,0.6683333333,1,2.3333333333,4,1,3,5,-1,0.6666666667,3]
[null,null,"Days in Hospital",{"$nulls":3},"4.00 (2.00,6.00)","3.32 (2.00,5.00)","0.67 (-1.00,3.00)",null,"1.00 (1.00,1.00)","1.00 (1.00,1.00)","0.00 (0.00,0.00)",null,"3.00 (1.00,5.00)","2.32 (1.00,4.00)","0.67 (-1.00,3.00)",8,"hospdays",3.3196666667,4,0.6683333333,2,3.3333333333,5,2,4,6,-1,0.6666666667,3,1,1,0,1,1,1,1,1,1,0,0,0,2.3196666667,3,0.6683333333,1,2.3333333333,4,1,3,5,-1,0.6666666667,3,null,3.3196666667,true,{"v":0,"d":"0.0000"}]
["UK & Ireland (n=9)"]
[null,"No. of FN Events",{"$nulls":4},"1.33 (1.00,1.67)","0.11 (0.00,0.33)","1.22 (0.78,1.67)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.33 (0.00,0.67)","0.11 (0.00,0.33)","0.22 (-0.22,0.67)",2,"fnevent",0.1096666667,1.334,1.2242222222,0,0.1111111111,0.3333333333,1,1.3333333333,1.6666666667,0.7777777778,1.2222222222,1.6666666667,0,1,1,0,0,0,1,1,1,1,1,1,0.1096666667,0.334,0.2242222222,0,0.1111111111,0.3333333333,0,0.3333333333,0.6666666667,-0.222222222,0.2222222222,0.6666666667]
[null,null,"Requiring Inpatient Care",{"$nulls":3},"1.33 (1.00,1.67)","0.11 (0.00,0.33)","1.22 (0.78,1.67)",null,"1.00 (1.00,1.00)","0.00 (0.00,0.00)","1.00 (1.00,1.00)",null,"0.33 (0.00,0.67)","0.11 (0.00,0.33)","0.22 (-0.22,0.67)",3,"fnhosp",0.1096666667,1.334,1.2242222222,0,0.1111111111,0.3333333333,1,1.3333333333,1.6666666667,0.7777777778,1.2222222222,1.6666666667,0,1,1,0,0,0,1,1,1,1,1,1,0.1096666667,0.334,0.2242222222,0,0.1111111111,0.3333333333,0,0.3333333333,0.6666666667,-0.222222222,0.2222222222,0.6666666667,null,0.1096666667,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Outpatient Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",4,"fnout",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Home Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",5,"fnhome",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Other Care/No Action",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",6,"fnoth",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,null,0,true,{"v":0,"d":"0.0000"}]
[null,null,"Requiring Unknown Care",{"$nulls":3},"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"0.00 (0.00,0.00)","0.00 (0.00,0.00)","0.00 (0.00,0.00)",null,"fnunkn",0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0]
[null,"FN-Related Inpatient Care",{"$nulls":15},7,null,3.333,4.3364444444,0.997,2.1111111111,3.3333333333,4.5555555556,3.1111111111,4.3333333333,5.4444444444,-1.333333333,1,3.2222222222,1,1,0,1,1,1,1,1,1,0,0,0,2.333,3.3364444444,0.997,1.1111111111,2.3333333333,3.5555555556,2.1111111111,3.3333333333,4.4444444444,-1.333333333,1,3.2222222222]
[null,null,"Days in Hospital",{"$nulls":3},"4.34 (3.11,5.44)","3.33 (2.11,4.56)","1.00 (-1.33,3.22)",null,"1.00 (1.00,1.00)","1.00 (1.00,1.00)","1.00 (1.00,1.00)",null,"3.34 (2.11,4.44)","2.33 (1.11,3.56)","1.00 (-1.33,3.22)",8,"hospdays",3.333,4.3364444444,0.997,2.1111111111,3.3333333333,4.5555555556,3.1111111111,4.3333333333,5.4444444444,-1.333333333,1,3.2222222222,1,1,0,1,1,1,1,1,1,0,0,0,2.333,3.3364444444,0.997,1.1111111111,2.3333333333,3.5555555556,2.1111111111,3.3333333333,4.4444444444,-1.333333333,1,3.2222222222,null,3.333,true,{"v":0,"d":"0.0000"}]
["*Mean levels of resource use from index cycle through end of the chemotherapy course"]

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[]
["Online Supplement -- Table S6.  Healthcare costs among FN patients and comparison patients matched on basis of age (±5 years), country of residence, tumor stage, bone marrow involvement, IPI/FLIPI score, and chemotherapy regimen"]
[]
[{"$nulls":6},"Mean (95% CI), in British pounds"]
[]
[{"$nulls":6},"Overall*",{"$nulls":3},"Index Cycle",{"$nulls":3},"Post-Index Cycles"]
[]
[{"$nulls":6},"FN","Comparison",null,null,"FN","Comparison",null,null,"FN","Comparison"]
[{"$nulls":6},"Patients","Patients",null,null,"Patients","Patients",null,null,"Patients","Patients",null,"rown","varname","stat1","stat12_5","stat197_5","stat2","stat22_5","stat297_5","stat3","stat32_5","stat397_5","stat4","stat42_5","stat497_5","stat5","stat52_5","stat597_5","stat6","stat62_5","stat697_5"]
["Healthcare Resources",{"$nulls":5},"(n=118)","(n=118)","Difference",null,"(n=118)","(n=118)","Difference",null,"(n=118)","(n=118)","Difference",1,"counter",118,"xxx","xxx",118,"xxx","xxx",{"$nulls":3},118,"xxx","xxx",118,"xxx","xxx",{"$nulls":3},118,"xxx","xxx",118,"xxx","xxx"]
["Total Cost of FN, Overall",{"$nulls":5},"7,987 (6,745, 9,426)","2,360 (1,819, 2,912)","5,624 (4,191, 7,170)",null,"3,785 (3,162, 4,527)","---","3,785 (3,162, 4,527)",null,"4,202 (3,244, 5,343)","2,360 (1,819, 2,912)","1,843 (696, 3,150)","meanvar1",2,2363.4278277629846,7987.305762940514,5662.7391166075595,1820.4137563122372,2354.228790324091,2913.8799235326987,6744.9993760185835,7967.7156613094485,9425.8090940906,4191.189311562686,5677.5378374067195,7169.889823046939,3.5762896551724364,3784.827067120815,3789.8251368177234,0,3.686896551724138,11.060689655172414,3161.7988914128136,3769.4047801749184,4527.4757611129935,3126.995121579001,3783.3231933209545,4494.288968406385,2359.8515381078114,4202.478695819703,1872.9139797898395,1818.570308036375,2352.1492209951875,2912.0364752568366,3243.6343208343887,4164.221644853595,5343.374053369162,696.0999864423234,1874.3258914366497,3149.7243255489616]
[null,"Inpatient Care",{"$nulls":4},"5,958 (4,741, 7,395)","362 (98, 720)","5,596 (4,194, 7,013)",null,"3,680 (3,059, 4,422)","---","3,680 (3,059, 4,422)",null,"2,278 (1,435, 3,288)","362 (98, 720)","1,916 (874, 2,979)","meanvar2",3,362.240653501386,5957.923727374213,5623.001811852711,97.5611280862069,358.95653455596283,719.9118568581063,4740.5991434198495,5943.13982897924,7394.7908474719225,4194.147630920177,5619.38135402769,7012.7409393908365,0,3680.1477301826358,3689.1614091302995,0,0,0,3058.7206958287024,3668.7824507266423,4422.201695448553,3016.604076064369,3679.9972850770628,4403.560930072631,362.240653501386,2277.7759971915793,1933.8404027224124,97.5611280862069,358.95653455596283,719.9118568581063,1434.6690900144358,2251.6084901046743,3288.453057613786,874.181176139994,1930.4688748141843,2979.1908323860275]
[null,"Outpatient Care",{"$nulls":4},"197 (91, 339)","123 (37, 250)","74 (-91, 248)",null,"61 (33, 93)","---","61 (33, 93)",null,"136 (34, 277)","123 (37, 250)","13 (-140, 187)","meanvar3",4,122.97869564091008,196.93434430213085,76.87025785850389,36.60576666551724,116.70966054159479,249.53939954870685,90.84158497586206,190.65274741314653,339.3514385353447,-90.67025483728449,76.07237257844828,247.91122217392243,0,60.92586124852715,60.44503130810999,0,0,0,32.618275337068965,60.12482533577587,92.95453816810344,32.844671072198274,59.63516565732759,92.25383876336205,122.97869564091008,136.00848305360338,16.42522655039395,36.60576666551724,116.70966054159479,249.53939954870685,34.133010012715516,130.33601437090516,276.9792468717672,-139.61065604935345,14.304573001077586,187.1883487025862]
[null,"Home Care",{"$nulls":4},"1,732 (1,351, 2,140)","1,762 (1,398, 2,157)","-34 (-566, 489)",null,"38 (17, 63)","---","38 (17, 63)",null,"1,694 (1,320, 2,102)","1,762 (1,398, 2,157)","-68 (-600, 448)","meanvar4",5,1766.054622758618,1732.4754257469308,-25.56545241399776,1405.7581034482762,1766.0378448275865,2162.1940517241383,1350.944454022888,1732.1852298849572,2139.9129310341814,-566.4574137931033,-26.378045977112016,489.4438505743101,3.5762896551724364,37.9908118965517,34.5024746551724,0,3.686896551724138,11.060689655172414,17.259310344827586,37.40060344827586,62.69137931034483,12.74896551724138,33.79448275862069,60.4196551724138,1762.478333103448,1694.4846138503785,-60.067927069170175,1398.4109482758622,1761.1900862068965,2156.6787931034482,1320.031436781509,1693.468534482458,2102.1833620686643,-600.2543390805604,-66.15094827586213,448.0317528733618]
[null,"Other/Unknown Care",{"$nulls":4},"100 (25, 195)","112 (24, 234)","-12 (-163, 118)",null,"6 (3, 9)","---","6 (3, 9)",null,"94 (19, 188)","112 (24, 234)","-18 (-168, 112)","meanvar5",6,112.15385586206905,99.97226551724137,-11.567500689655184,23.803103448275863,106.25629310344827,234.4437068965517,25.483620689655172,97.2531896551724,194.6745689655173,-163.10491379310344,-10.298275862068962,117.77284482758621,0,5.762663793103462,5.716221724137934,0,0,0,2.7031034482758622,5.7155172413793105,9.363103448275861,2.6705172413793106,5.7155172413793105,9.297931034482758,112.15385586206905,94.20960172413793,-17.283722413793118,23.803103448275863,106.25629310344827,234.4437068965517,19.37094827586207,91.48060344827586,187.85931034482758,-168.41327586206893,-16.645517241379316,112.14844827586208]
["Total Cost of FN, by Setting of Care",{"$nulls":16},""]
[null,"Inpatient Episode",{"$nulls":4},"9,972 (8,422, 11,609)","2,475 (1,818, 3,204)","7,492 (5,821, 9,341)",null,"5,263 (4,525, 6,141)","---","5,263 (4,525, 6,141)",null,"4,709 (3,546, 6,044)","2,475 (1,818, 3,204)","2,233 (704, 3,820)","meanvar1",2,2480.4096473291734,9972.196875950287,7524.773791922259,1825.7704731182932,2472.470928003625,3206.7125669974257,8421.579576438355,9952.24765769902,11609.027519452447,5820.939824896879,7508.755715931242,9340.603315066679,5.090435121951173,5263.438246279395,5291.334811243637,0,5.215609756097561,15.646829268292683,4525.269187388196,5250.538524668211,6140.888878557557,4523.470045340247,5288.938783210386,6114.156462052375,2475.319212207222,4708.758629670889,2233.43898067862,1818.1784054365862,2467.564872949899,3204.104762119377,3545.5475125842095,4651.247741068028,6043.639272925067,703.5476992821988,2234.224316205803,3819.586448209565]
[null,"Outpatient Episode",{"$nulls":4},"4,164 (1,030, 7,651)","2,027 (1,086, 3,166)","2,137 (-1,285, 5,983)",null,"293 (293, 293)","---","293 (293, 293)",null,"3,871 (737, 7,357)","2,027 (1,086, 3,166)","1,844 (-1,578, 5,690)","meanvar1",2,2026.6188549194865,4163.90939046702,2169.9975633172658,1086.246765875,2016.7289737656251,3165.778120590625,1030.064294575,4061.6848437625,7650.74723354323,-1284.6217592125,2087.8915508151053,5983.2103884050375,0,293.27969140000477,293.27969140000477,0,0,0,293.2796914,293.2796914,293.2796914,293.2796914,293.2796914,293.2796914,2026.6188549194865,3870.629699067018,1876.7178719172655,1086.246765875,2016.7289737656251,3165.778120590625,736.784603175,3768.4051523625,7357.46754214323,-1577.9014506125,1794.6118594151058,5689.930697005038]
[null,"Home Care Episode",{"$nulls":4},"3,836 (2,214, 6,166)","2,274 (1,265, 3,434)","1,562 (-496, 3,811)",null,"190 (168, 232)","---","190 (168, 232)",null,"3,645 (2,003, 5,985)","2,274 (1,265, 3,434)","1,371 (-701, 3,634)","meanvar1",2,2273.866583903213,3835.6636130530355,1557.7572003328585,1265.148158885714,2269.464118492857,3434.3949218999996,2214.4647288396427,3718.3796236505164,6166.0253225535935,-496.344582992857,1534.9349161325604,3810.7846760651205,0,190.4879314285712,190.49321142857127,0,0,0,168,186.54857142857145,232.01142857142855,168,190.73142857142855,227.82857142857142,2273.866583903213,3645.175681624464,1367.26398890429,1265.148158885714,2269.464118492857,3434.3949218999996,2003.4855146682148,3524.974658383472,5984.56817969645,-700.5331544214284,1357.2843700662308,3633.510390350835]
[null,"Other/Unknown Episode",{"$nulls":4},"1,750 (746, 2,892)","1,857 (592, 3,466)","-107 (-1,846, 1,718)",null,"139 (51, 313)","---","139 (51, 313)",null,"1,611 (622, 2,744)","1,857 (592, 3,466)","-246 (-1,930, 1,594)","meanvar1",2,1857.225437231735,1750.2744062071686,-108.7037720539833,591.5633333333334,1795.0836287666666,3465.6666192916664,746.0433076166667,1689.2399871416667,2892.4341538083327,-1845.5351734333333,-77.89066395833329,1717.9044837583333,0,139.3187600000004,138.41864000000027,0,0,0,51,139.04,312.68000000000006,51,139.04,307.8,1857.225437231735,1610.9556462071673,-247.12241205398323,591.5633333333334,1795.0836287666666,3465.6666192916664,622.3041152333333,1551.70914095,2744.4916409499997,-1929.7544878166668,-242.81919238333307,1594.3344966166665]
["*Mean costs from index cycle through end of the chemotherapy course"]

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[]
["Online Supplement -- Table S7.  Healthcare costs among FN patients and matched comparison patients, excluding hospital admissions designated as \"elective\" from calculation of unit costs"]
[]
[{"$nulls":6},"Mean (95% CI), in British pounds"]
[]
[{"$nulls":6},"Overall*",{"$nulls":3},"Index Cycle",{"$nulls":3},"Post-Index Cycles"]
[]
[{"$nulls":6},"FN","Comparison",null,null,"FN","Comparison",null,null,"FN","Comparison"]
[{"$nulls":6},"Patients","Patients",null,null,"Patients","Patients",null,null,"Patients","Patients",null,"rown","varname","stat1","stat12_5","stat197_5","stat2","stat22_5","stat297_5","stat3","stat32_5","stat397_5","stat4","stat42_5","stat497_5","stat5","stat52_5","stat597_5","stat6","stat62_5","stat697_5"]
["Healthcare Resources",{"$nulls":5},"(n=295)","(n=295)","Difference",null,"(n=295)","(n=295)","Difference",null,"(n=295)","(n=295)","Difference",1,"counter",295,"xxx","xxx",295,"xxx","xxx",{"$nulls":3},295,"xxx","xxx",295,"xxx","xxx",{"$nulls":3},295,"xxx","xxx",295,"xxx","xxx"]
["Total Cost of FN, Overall",{"$nulls":5},"7,377 (6,646, 8,133)","2,241 (1,890, 2,600)","5,132 (4,370, 6,006)",null,"3,603 (3,199, 4,048)","---","3,603 (3,199, 4,048)",null,"3,774 (3,195, 4,410)","2,241 (1,890, 2,600)","1,533 (846, 2,236)","meanvar1",2,2245.0999606441906,7377.05982003295,5163.798891313227,1892.534149104964,2241.473816141037,2604.4569096363066,6645.727640813742,7371.688728328895,8132.542864291181,4369.691253463767,5151.8708568676175,6005.552878912845,3.982900546075075,3602.8977751836383,3606.679615319712,0,4.088941979522184,10.80716723549488,3198.840512448716,3600.4920382440587,4048.1275846777776,3198.8016030599815,3600.890663972642,4044.2122087153884,2241.1170600981145,3774.16204484932,1557.11927599351,1890.1636801985835,2237.064024726483,2599.517804529223,3195.2545273310548,3764.443307131336,4410.137984093037,846.0445718692308,1557.1182410651018,2236.2470033414106]
[null,"Inpatient Care",{"$nulls":4},"5,318 (4,647, 6,030)","494 (255, 779)","4,823 (4,131, 5,620)",null,"3,493 (3,080, 3,935)","---","3,493 (3,080, 3,935)",null,"1,824 (1,290, 2,375)","494 (255, 779)","1,330 (769, 1,922)","meanvar2",3,494.44682257053944,5317.528065842165,4846.021052906328,254.84648633354777,485.52949123921326,779.1270656319575,4647.289190993883,5310.19460314975,6030.311860067157,4131.398784753992,4845.215584993512,5619.839236724238,0,3493.403978781417,3501.5543066702353,0,0,0,3080.225335832726,3490.036070412417,3934.841168759721,3092.100195431838,3493.2341054758663,3940.586573789521,494.44682257053944,1824.1240870607432,1344.4667462360844,254.84648633354777,485.52949123921326,779.1270656319575,1289.7115771425056,1815.670023355168,2374.6846574175024,768.5267774633687,1344.4055899879186,1922.1530282255176]
[null,"Outpatient Care",{"$nulls":4},"180 (123, 252)","130 (56, 219)","50 (-37, 144)",null,"65 (43, 89)","---","65 (43, 89)",null,"115 (62, 182)","130 (56, 219)","-15 (-97, 74)","meanvar3",4,129.90974095293853,179.75269822955843,52.411494733340355,55.78018353071673,127.9184519267918,218.69008819402734,122.62574739006821,176.98506072522184,251.84879560895905,-37.338790693498275,54.01259348247439,144.0455199717576,0,64.78712237491749,64.4262977962348,0,0,0,43.25895173148463,63.92921963361772,89.43296588300336,42.95971198730374,63.92502423943682,90.63312415726955,129.90974095293853,114.96557585464107,-12.01480306289454,55.78018353071673,127.9184519267918,218.69008819402734,62.11644357602388,111.77215066919791,182.34269344854943,-96.90888185307165,-10.929206244283275,74.36125125162116]
[null,"Home Care",{"$nulls":4},"1,673 (1,452, 1,899)","1,447 (1,220, 1,674)","221 (-78, 545)",null,"41 (26, 59)","---","41 (26, 59)",null,"1,632 (1,409, 1,853)","1,447 (1,220, 1,674)","184 (-117, 503)","meanvar4",5,1451.3517175985291,1672.8503535721602,226.16266517527094,1225.6554678289262,1447.9481038046943,1675.1963782578514,1451.860014220667,1670.0584584754629,1899.194118316111,-77.71815130846377,217.48443516641646,544.5154229301534,3.982900546075075,41.03730174061437,37.019201843003444,0,4.088941979522184,10.80716723549488,25.648088737201363,40.64528156996586,58.57141638225256,20.699283276450508,36.84383105802047,56.06493174061433,1447.3688170524504,1631.8130518315484,189.14346333226771,1220.343287523295,1442.5888887876295,1673.7541788900185,1408.6902389078514,1627.2832992036026,1852.964243458398,-116.83455401293506,181.00364818612627,502.8281496146932]
[null,"Other/Unknown Care",{"$nulls":4},"207 (135, 293)","169 (97, 253)","38 (-67, 152)",null,"4 (2, 5)","---","4 (2, 5)",null,"203 (131, 289)","169 (97, 253)","34 (-71, 148)","meanvar5",6,169.3916795221845,206.9287023890784,39.203678498293485,96.87412969283275,167.30901023890786,252.8940955631399,135.24010238907852,205.3676791808874,292.8539590443687,-67.34378839590441,39.42689419795222,151.82569965870306,0,3.6693722866894114,3.679809010238907,0,0,0,2.214470989761092,3.6552901023890785,5.247645051194539,2.0887372013651877,3.6552901023890785,5.286348122866894,169.3916795221845,203.25933010238913,35.52386948805459,96.87412969283275,167.30901023890786,252.8940955631399,130.88856655290104,201.84365187713314,288.7248122866895,-70.83791808873717,35.95546075085325,148.33443686006825]
["Total Cost of FN, by Setting of Care",{"$nulls":16},""]
[null,"Inpatient Episode",{"$nulls":4},"8,809 (7,906, 9,708)","2,378 (1,950, 2,853)","6,428 (5,537, 7,315)",null,"4,688 (4,224, 5,187)","---","4,688 (4,224, 5,187)",null,"4,121 (3,384, 4,872)","2,378 (1,950, 2,853)","1,743 (1,049, 2,510)","meanvar1",2,2381.440316949059,8809.194399281356,6430.98627292665,1953.2525787835057,2371.80044908511,2856.990605763529,7906.062728039756,8800.954971194693,9708.165744122312,5537.2990069254465,6429.338608310658,7315.134737864833,3.377820000000011,4688.375987365372,4689.161175355261,0,3.4858823529411764,10.457647058823529,4224.115738801942,4684.149501973705,5187.306814677958,4196.103773644352,4688.155545808795,5172.612652277392,2378.0624969490555,4120.818411915995,1741.8250975713945,1949.766696430565,2367.063184463009,2852.7116423062894,3384.1048368470765,4123.968853485872,4871.503341239656,1048.9493403900858,1743.4084258629143,2509.874570702711]
[null,"Outpatient Episode",{"$nulls":4},"3,582 (1,892, 5,602)","1,750 (1,115, 2,464)","1,832 (-171, 3,817)",null,"341 (293, 435)","---","341 (293, 435)",null,"3,242 (1,497, 5,292)","1,750 (1,115, 2,464)","1,491 (-495, 3,515)","meanvar1",2,1750.1522020000116,3582.351818567917,1809.9074273995273,1114.6513170838234,1736.8647722764706,2464.187126227941,1892.3076087529412,3584.9443086,5601.904950670588,-171.45995783529395,1803.2430896794117,3816.8042221044116,0,340.7266896825308,339.9241036419305,0,0,0,293.2796914,340.49063496470586,434.91252209411766,293.2796914,340.49063496470586,434.91252209411766,1750.1522020000116,3241.625128885387,1469.9833237575974,1114.6513170838234,1736.8647722764706,2464.187126227941,1497.4563118588235,3236.5290062294116,5292.439257358823,-494.6308723191176,1453.6414267235293,3515.4161089176478]
[null,"Home Care Episode",{"$nulls":4},"3,224 (2,430, 4,207)","1,814 (989, 2,895)","1,410 (195, 2,421)",null,"324 (241, 415)","---","324 (241, 415)",null,"2,900 (2,119, 3,897)","1,814 (989, 2,895)","1,086 (-111, 2,086)","meanvar1",2,1814.3975513459825,3224.21137795347,1400.7728375781383,989.3158999914285,1792.9350517335715,2894.58860294,2429.7376581028566,3172.9330657599985,4206.744744269143,194.6719960887143,1398.737848192286,2420.9450898138575,0,324.0514694437828,325.15981352373694,0,0,0,241.3045626114286,322.31957306857146,414.9820956228571,239.49169501142853,324.08209398285715,416.1054454571428,1814.3975513459825,2900.1599085096823,1075.6130240543998,989.3158999914285,1792.9350517335715,2894.58860294,2118.776852986285,2850.6042950374276,3897.178571427571,-110.60664090971423,1081.9458897971429,2085.664371982714]
[null,"Other/Unknown Episode",{"$nulls":4},"2,106 (1,103, 3,208)","1,752 (727, 2,966)","333 (-863, 1,504)",null,"104 (51, 205)","---","104 (51, 205)",null,"2,003 (1,010, 3,116)","1,752 (727, 2,966)","251 (-947, 1,421)","meanvar1",2,1773.6825201402598,2106.4114788053084,341.2263273212196,744.34951722,1750.4824696,2997.5693783300003,1103.41515168,2093.40199295,3207.766492285,-863.3125077149998,333.45991262999996,1504.02005552,21.597839999999845,103.57159199999924,81.9796080000001,0,21.384,64.152,51,103.824,205.08,-10.224,79.512,203.616,1752.0846801402572,2002.8398868053075,259.2467193212204,727.0259021400002,1729.2330741199999,2965.93548285,1009.9855160949999,1990.9880160950001,3116.4149768549996,-947.0201276650001,250.5936223350002,1421.36568557]
["*Mean costs from index cycle through end of the chemotherapy course"]
["**Long stay hospitalizations estimated to cost $4,318 for up to 6 days; $561 for each subsequent day"]

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[]
["Online Supplement -- Table S8.  Healthcare costs among FN patients and matched comparison patients, using PbR tariffs as basis of unit cost of hospital care"]
[]
[{"$nulls":6},"Mean (95% CI), in British pounds"]
[]
[{"$nulls":6},"Overall*",{"$nulls":3},"Index Cycle",{"$nulls":3},"Post-Index Cycles"]
[]
[{"$nulls":6},"FN","Comparison",null,null,"FN","Comparison",null,null,"FN","Comparison"]
[{"$nulls":6},"Patients","Patients",null,null,"Patients","Patients",null,null,"Patients","Patients",null,"rown","varname","stat1","stat12_5","stat197_5","stat2","stat22_5","stat297_5","stat3","stat32_5","stat397_5","stat4","stat42_5","stat497_5","stat5","stat52_5","stat597_5","stat6","stat62_5","stat697_5"]
["Healthcare Resources",{"$nulls":5},"(n=295)","(n=295)","Difference",null,"(n=295)","(n=295)","Difference",null,"(n=295)","(n=295)","Difference",1,"counter",295,"xxx","xxx",295,"xxx","xxx",{"$nulls":3},295,"xxx","xxx",295,"xxx","xxx",{"$nulls":3},295,"xxx","xxx",295,"xxx","xxx"]
["Total Cost of FN, Overall",{"$nulls":5},"6,609 (6,023, 7,231)","2,144 (1,839, 2,459)","4,461 (3,828, 5,177)",null,"3,075 (2,805, 3,352)","---","3,075 (2,805, 3,352)",null,"3,534 (3,021, 4,099)","2,144 (1,839, 2,459)","1,390 (790, 2,011)","meanvar1",2,2147.8440616680828,6608.578306381072,4481.919082780813,1842.8856105042341,2150.148773304194,2463.503305020682,6023.1473791936205,6598.221690526199,7230.738763042819,3827.899165341013,4476.267212475552,5176.831361335653,3.982900546075075,3074.903182350873,3070.1688183913916,0,4.088941979522184,10.80716723549488,2804.781178029946,3076.36382,3351.690252106053,2795.956537864021,3072.8335093255773,3347.0073097660584,2143.861161122005,3533.6751240302087,1411.750264389414,1838.6516514598657,2147.9260725566373,2458.698851365955,3020.8069146958856,3529.0891621241976,4099.366025483909,790.0214090564325,1408.7035164100103,2011.3908054447265]
[null,"Inpatient Care",{"$nulls":4},"4,549 (4,033, 5,110)","397 (218, 600)","4,152 (3,597, 4,749)",null,"2,965 (2,688, 3,244)","---","2,965 (2,688, 3,244)",null,"1,584 (1,145, 2,061)","397 (218, 600)","1,186 (734, 1,679)","meanvar2",3,397.19092359443016,4549.046552190294,4164.141244373903,217.56601474301874,394.8253935240068,600.4615880936656,4033.1537333429683,4529.830224845406,5109.950886846365,3596.6484563034155,4160.636005078548,4749.285610190846,0,2965.4093859486557,2965.0435097419168,0,0,0,2688.4837007553047,2964.156818602759,3243.54820829365,2678.581913038852,2969.0595711771984,3251.9948290954408,397.19092359443016,1583.6371662416307,1199.0977346319853,217.56601474301874,394.8253935240068,600.4615880936656,1145.0467237793823,1577.353705071101,2060.85151996261,734.1966096229013,1195.7868616976928,1678.9103666316878]
[null,"Outpatient Care",{"$nulls":4},"180 (123, 252)","130 (56, 219)","50 (-37, 144)",null,"65 (43, 89)","---","65 (43, 89)",null,"115 (62, 182)","130 (56, 219)","-15 (-97, 74)","meanvar3",4,129.90974095293853,179.75269822955843,52.411494733340355,55.78018353071673,127.9184519267918,218.69008819402734,122.62574739006821,176.98506072522184,251.84879560895905,-37.338790693498275,54.01259348247439,144.0455199717576,0,64.78712237491749,64.4262977962348,0,0,0,43.25895173148463,63.92921963361772,89.43296588300336,42.95971198730374,63.92502423943682,90.63312415726955,129.90974095293853,114.96557585464107,-12.01480306289454,55.78018353071673,127.9184519267918,218.69008819402734,62.11644357602388,111.77215066919791,182.34269344854943,-96.90888185307165,-10.929206244283275,74.36125125162116]
[null,"Home Care",{"$nulls":4},"1,673 (1,452, 1,899)","1,447 (1,220, 1,674)","221 (-78, 545)",null,"41 (26, 59)","---","41 (26, 59)",null,"1,632 (1,409, 1,853)","1,447 (1,220, 1,674)","184 (-117, 503)","meanvar4",5,1451.3517175985291,1672.8503535721602,226.16266517527094,1225.6554678289262,1447.9481038046943,1675.1963782578514,1451.860014220667,1670.0584584754629,1899.194118316111,-77.71815130846377,217.48443516641646,544.5154229301534,3.982900546075075,41.03730174061437,37.019201843003444,0,4.088941979522184,10.80716723549488,25.648088737201363,40.64528156996586,58.57141638225256,20.699283276450508,36.84383105802047,56.06493174061433,1447.3688170524504,1631.8130518315484,189.14346333226771,1220.343287523295,1442.5888887876295,1673.7541788900185,1408.6902389078514,1627.2832992036026,1852.964243458398,-116.83455401293506,181.00364818612627,502.8281496146932]
[null,"Other/Unknown Care",{"$nulls":4},"207 (135, 293)","169 (97, 253)","38 (-67, 152)",null,"4 (2, 5)","---","4 (2, 5)",null,"203 (131, 289)","169 (97, 253)","34 (-71, 148)","meanvar5",6,169.3916795221845,206.9287023890784,39.203678498293485,96.87412969283275,167.30901023890786,252.8940955631399,135.24010238907852,205.3676791808874,292.8539590443687,-67.34378839590441,39.42689419795222,151.82569965870306,0,3.6693722866894114,3.679809010238907,0,0,0,2.214470989761092,3.6552901023890785,5.247645051194539,2.0887372013651877,3.6552901023890785,5.286348122866894,169.3916795221845,203.25933010238913,35.52386948805459,96.87412969283275,167.30901023890786,252.8940955631399,130.88856655290104,201.84365187713314,288.7248122866895,-70.83791808873717,35.95546075085325,148.33443686006825]
["Total Cost of FN, by Setting of Care",{"$nulls":16},""]
[null,"Inpatient Episode",{"$nulls":4},"7,800 (7,095, 8,507)","2,263 (1,891, 2,650)","5,534 (4,898, 6,245)",null,"3,986 (3,683, 4,275)","---","3,986 (3,683, 4,275)",null,"3,814 (3,208, 4,452)","2,263 (1,891, 2,650)","1,551 (987, 2,209)","meanvar1",2,2266.2939952296006,7800.302547697653,5540.039381071452,1897.6175717002434,2266.5961798588623,2651.811927376308,7095.448529558829,7793.6658564596255,8506.679934926848,4897.9233154075555,5524.7328027060175,6244.7184338798625,3.377820000000011,3985.9737335192226,3985.7561070294714,0,3.4858823529411764,10.457647058823529,3682.9031278740713,3983.0618080741833,4274.697018783252,3680.3812664004954,3991.9812407469663,4277.289930486628,2262.9161752296027,3814.328814178434,1554.2832740419794,1890.6831722199743,2262.2194124277344,2650.0689861998376,3208.396496333048,3814.9922164654204,4451.554499359585,987.1031736283392,1542.7959018642937,2209.055444099354]
[null,"Outpatient Episode",{"$nulls":4},"3,514 (1,866, 5,495)","1,689 (1,113, 2,302)","1,825 (-104, 3,740)",null,"341 (293, 435)","---","341 (293, 435)",null,"3,173 (1,457, 5,146)","1,689 (1,113, 2,302)","1,485 (-433, 3,446)","meanvar1",2,1688.7634608235417,3514.1737009208555,1804.2017626936433,1113.0904775852941,1682.476617679412,2302.2129003279415,1866.264787135294,3510.816408935294,5494.7782730882345,-104.32242457205876,1793.477509080882,3739.7437700852943,0,340.7266896825308,339.9241036419305,0,0,0,293.2796914,340.49063496470586,434.91252209411766,293.2796914,340.49063496470586,434.91252209411766,1688.7634608235417,3173.4470112383237,1464.277659051715,1113.0904775852941,1682.476617679412,2302.2129003279415,1457.2044185176474,3161.075374094118,5146.477091158823,-433.11910761323526,1449.7863477970586,3446.464078685294]
[null,"Home Care Episode",{"$nulls":4},"3,169 (2,421, 4,021)","1,769 (974, 2,785)","1,400 (187, 2,421)",null,"324 (241, 415)","---","324 (241, 415)",null,"2,845 (2,121, 3,735)","1,769 (974, 2,785)","1,076 (-115, 2,088)","meanvar1",2,1768.9508942031262,3169.0207379534663,1392.2753575781392,973.774338255,1740.0950063314285,2785.49577074,2421.1751448761424,3125.9482910078564,4020.757799445999,187.29913894585724,1387.045284703714,2421.3889783028576,0,324.0514694437828,325.15981352373694,0,0,0,241.3045626114286,322.31957306857146,414.9820956228571,239.49169501142853,324.08209398285715,416.1054454571428,1768.9508942031262,2844.969268509682,1067.1155440544014,973.774338255,1740.0950063314285,2785.49577074,2120.5388575218567,2805.4867488047144,3734.9849480977136,-114.83806948114275,1075.384894768143,2087.844371982714]
[null,"Other/Unknown Episode",{"$nulls":4},"2,125 (1,103, 3,248)","1,765 (736, 2,990)","338 (-858, 1,524)",null,"104 (51, 205)","---","104 (51, 205)",null,"2,022 (1,015, 3,153)","1,765 (736, 2,990)","256 (-953, 1,437)","meanvar1",2,1786.8985051402578,2125.308603805311,346.72166232122015,750.0803836100001,1760.9174696000002,3010.9218783300003,1103.41515168,2109.14570635,3248.170976855,-858.02124472,342.8494351800001,1523.83102512,21.597839999999845,103.57159199999924,81.9796080000001,0,21.384,64.152,51,103.824,205.08,-10.224,79.512,203.616,1765.300665140261,2021.7370118053086,264.74205432122034,736.4509021400002,1747.28811377,2989.6415794,1014.841500665,2009.5821593949995,3152.9819845700003,-952.82822178,254.18929754999994,1436.8215061300002]
["*Mean costs from index cycle through end of the chemotherapy course"]
["**Long stay hospitalizations estimated to cost $4,506.50 for up to 17 days; $299 for each subsequent day"]