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["Additional File 1: iTT548 Model details"]
[]
["A1","List of reactions in iTT548"]
[]
["A2","List of metabolites in iTT548"]
[]
["A3","List of new annotations"]
[]
["A4","List of reactions added during Gap-Fill"]

{"sheet":"A1","index":1,"n_rows":870,"n_cols":7,"rows_kept":870,"flags":["formulas_cached_only"]}
["Abbreviation","Name","Reaction","GPR","Protein","Subsystem","EC. Number"]
["R001","Biomass reaction (70 C)","0.1582 L_ASP[c] + 0.2696 L_GLU[c] + 0.2076 L_SER[c] + 0.0375 L_HIS[c] + 0.4716 L_GLY[c] + 0.1531 L_THR[c] + 0.3231 L_ARG[c] + 0.5434 L_ALA[c] + 0.1052 L_TYR[c] + 0.1668 L_VAL[c] + 0.1322 L_PHE[c] + 0.0593 L_ILE[c] + 0.3744 L_LEU[c] + 0.1337 L_LYS[c] + 0.2898 L_PRO[c] + 0.1582 L_ASN[c] + 0.0134 L_CYS[c] + 0.2714 L_GLN[c] + 0.0224 L_MET[c] + 0.0654 L_TRP[c] + 0.0110 UDP_ACMURM[c] + 0.0110 UDP_AGLUAM[c] + 0.0110 D_GLU[c] + 0.0110 ORT[c] + 0.0259 D_ALA[c] + 0.0098 dTTP[c] + 0.0223 dGTP[c] + 0.0223 dCTP[c] + 0.0098 dATP[c] + 0.0586 CTP[c] + 0.1455 GTP[c] + 0.0976 UTP[c] + 0.01095 MGDG[c] + 0.0091 DGDG[c] + 0.1113 tZXT[c] + 0.0031 PETHA[c] + 0.0022 PGLY[c] + 0.0066 PINS[c] + 0.0012 CDLPN[c] + 0.0404 PX[c] + 59.81 ATP[c] -> 59.81 ADP[c] + 59.81 Pi[c] + 0.3659 PPi[c] ",null,null,"Exchange Reactions"]
["R002","ATP Maintenance","ATP[c] + H2O[c]  -> ADP[c] + Pi[c] + H[c] ",null,null,"Uassigned"]
["R003","ATP:D-glucose 6-phosphotransferase","ATP[c] + D_GLC[c]  -> ADP[c] + H[c] + G6P[c] ","TTC1688","glk","Glycolysis/Gluconeogenesis","2.7.1.2"]
["R004","ATP:D-glucose 6-phosphotransferase","ATP[c] + D_MAN[c]  -> ADP[c] + H[c] + M6P[c] ","TTC1688","glk","Glycolysis/Gluconeogenesis","2.7.1.2"]
["R005","D-glucose-6-phosphate aldose-ketose-isomerase","G6P[c]  <=> F6P[c] ","TTC1710","pgI","Glycolysis/Gluconeogenesis","5.3.1.9"]
["R006","ATP:D-fructose-6-phosphate 1-phosphotransferase","ATP[c] + F6P[c]  -> ADP[c] + H[c] + FBP[c] ","TTC1597","pfkA","Glycolysis/Gluconeogenesis","2.7.1.11"]
["R007","D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)","FBP[c]  <=> DHAP[c] + GAP[c] ","TTC1414","fbaB","Glycolysis/Gluconeogenesis","4.1.2.13"]
["R008","D-glyceraldehyde-3-phosphate aldose-ketose-isomerase","GAP[c]  <=> DHAP[c] ","TTC0581","tpiA","Glycolysis/Gluconeogenesis","5.3.1.1"]
["R009","D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)","NAD[c] + Pi[c] + GAP[c]  <=> H[c] + 13BPG[c] + NADH[c] ","TTC0549","gapA","Glycolysis/Gluconeogenesis","1.2.1.12"]
["R010","ATP:3-phospho-D-glycerate 1-phosphotransferase","ATP[c] + 3PG[c]  <=> ADP[c] + 13BPG[c] ","TTC0550","pgk","Glycolysis/Gluconeogenesis","2.7.2.3"]
["R011","2-Phospho-D-glycerate 2,3-phosphomutase","2PG[c]  <=> 3PG[c] ","(TTC1888 or TTC1618 or TTC1956 or TT_P0006)","gpmA","Glycolysis/Gluconeogenesis","5.4.2.1"]
["R012","2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)","H2O[c] + PEP[c]  <=> 2PG[c] ","TTC1610","eno","Glycolysis/Gluconeogenesis","4.2.1.11"]
["R013","ATP:pyruvate 2-O-phosphotransferase","ADP[c] + H[c] + PEP[c]  -> ATP[c] + PYR[c] ","TTC1611","pykA","Glycolysis/Gluconeogenesis","2.7.1.40"]
["R014","ATP:oxaloacetate carboxy-lyase (transphosphorylating;phosphoenolpyruvate-forming)","ATP[c] + OAC[c]  -> ADP[c] + PEP[c] + CO2[c] ","TTC1709","pckA","Glycolysis/Gluconeogenesis","4.1.1.49"]
["R015","(S)-Lactate:NAD+ oxidoreductase","H[c] + NADH[c] + PYR[c]  -> NAD[c] + LAC[c] ","TTC0748","ldh","Glycolysis/Gluconeogenesis","1.1.1.27"]
["R016","Acetate:CoA ligase (AMP-forming)","ATP[c] + CoA[c] + AC[c]  -> PPi[c] + AMP[c] + ACoA[c] ","(TTC0884 and TTC0885 and TTC0886 and TTC0919)","acsA ","Glycolysis/Gluconeogenesis","6.2.1.1"]
["R017","Acetaldehyde:NAD+ oxidoreductase","NAD[c] + H2O[c] + AALD[c]  -> 2 H[c] + NADH[c] + AC[c] ","(TTC0513 or TTC0604)","ald","Glycolysis/Gluconeogenesis","1.2.1.3"]
["R018","ethanol:NAD+ oxidoreductase","NAD[c] + ETH[c]  <=> H[c] + NADH[c] + AALD[c] ","TTC1572","adh","Glycolysis/Gluconeogenesis","1.1.1.1"]
["R019","acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)","H2O[c] + OAC[c] + ACoA[c]  -> CoA[c] + H[c] + CIT[c] ","TTC0978","gltA","Citric Acid Cycle","2.3.3.1"]
["R020","citrate hydro-lyase (cis-aconitate-forming)","CIT[c]  <=> H2O[c] + cACO[c] ","TTC0374","acnA","Citric Acid Cycle","4.2.1.3"]
["R021","isocitrate hydro-lyase (cis-aconitate-forming)","ICIT[c]  <=> H2O[c] + cACO[c] ","TTC0374","acnB","Citric Acid Cycle","4.2.1.3"]
["R022","Isocitrate:NADP+ oxidoreductase","NADP[c] + ICIT[c]  -> H[c] + OXLSUCC[c] + NADPH[c] ","TTC1172","idh1","Citric Acid Cycle","1.1.1.42"]
["R023","oxalosuccinate carboxy-lyase (2-oxoglutarate-forming)","H[c] + OXLSUCC[c]  -> CO2[c] + AKG[c] ","TTC1172","idh2","Citric Acid Cycle","1.1.1.42"]
["R024","2-oxoglutarate:ferredoxin oxidoreductase (decarboxylating)","NAD[c] + CoA[c] + AKG[c]  -> NADH[c] + CO2[c] + SUCCoA[c] ","(TTC1591 and TTC1592)","korB","Citric Acid Cycle","1.2.7.3"]
["R025","Succinate:CoA ligase (ADP-forming)","ATP[c] + CoA[c] + SUCC[c]  <=> ADP[c] + Pi[c] + SUCCoA[c] ","(TTC0169 and TTC0170)","sco","Citric Acid Cycle","6.2.1.5"]
["R026","Succinate:(acceptor) oxidoreductase","SUCC[c] + FAD[c]  <=> FADH2[c] + FUM[c] ","(TTC1089 and TTC1090 and TTC1091 and TTC1092)","sdh","Citric Acid Cycle","1.3.99.1"]
["R027","(S)-malate hydro-lyase (fumarate-forming)","MAL[c]  <=> H2O[c] + FUM[c] ","TTC0190","fumC","Citric Acid Cycle","4.2.1.2"]
["R028","(S)-malate:NAD+ oxidoreductase","NAD[c] + MAL[c]  <=> H[c] + NADH[c] + OAC[c] ","TTC0168","mqo","Citric Acid Cycle","1.1.1.37"]
["R029","D-glucose:ubiquinone oxidoreductase","D_GLC[c] + MQ[c]  -> GLC_LACN[c] + MQL[c] ","TTC0202",null,"Pentose Phosphate Pathway","1.1.5.2"]
["R030","D-Fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase","F6P[c] + GAP[c]  <=> E4P[c] + XYL5P[c] ","TTC1896","tktB","Pentose Phosphate Pathway","2.2.1.1"]
["R031","sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase","GAP[c] + SEDHEP7P[c]  <=> F6P[c] + E4P[c] ","TTC0701","tal","Pentose Phosphate Pathway","2.2.1.2"]
["R032","Sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase","GAP[c] + SEDHEP7P[c]  <=> XYL5P[c] + R5P[c] ","TTC1896","tktA","Pentose Phosphate Pathway","2.2.1.1"]
["R033","D-Ribulose-5-phosphate 3-epimerase","RBL5P[c]  <=> XYL5P[c] ","TTC1898","rpe","Pentose Phosphate Pathway","5.1.3.1"]
["R034","D-ribose-5-phosphate aldose-ketose-isomerase","R5P[c]  <=> RBL5P[c] ","TTC0932","rpiA","Pentose Phosphate Pathway","5.3.1.6"]
["R035","ATP:D-ribose-5-phosphate diphosphotransferase","ATP[c] + R5P[c]  <=> H[c] + AMP[c] + PRPP[c] ","(TTC1184 or TTC1274)","hisG","Pentose Phosphate Pathway","2.7.6.1"]
["R036","D-Ribose 1,5-phosphomutase","R1P[c]  <=> R5P[c] ","(TTC1630 or TTC1659)","pgm","Pentose Phosphate Pathway","5.4.2.2 or 5.4.2.7"]
["R037","ATP:D-ribose 5-phosphotransferase","ATP[c] + D_RIB[c]  -> ADP[c] + H[c] + R5P[c] ","TTC0063",null,"Pentose Phosphate Pathway","2.7.1.15"]
["R038","2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming)","dR5P[c]  -> GAP[c] + AALD[c] ","TTC0823",null,"Pentose Phosphate Pathway","4.1.2.4"]
["R039","2-deoxy-D-ribose 1-phosphate 1,5-phosphomutase","dR1P[c]  <=> dR5P[c] ","TTC1659",null,"Pentose Phosphate Pathway","5.4.2.7"]
["R040","glyceraldehyde ferredoxin oxidoreductase","NAD[c] + H2O[c] + GLYALD[c]  <=> 2 H[c] + NADH[c] + D_GLCT[c] ","TTC1834",null,"Pentose Phosphate Pathway","1.2.7.5"]
["R041","2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase","DHY_DOP_GLUCN[c]  -> GAP[c] + PYR[c] ","TT_P0030",null,"Pentose Phosphate Pathway","4.1.2.14"]
["R042","2-Dehydro-3-deoxy-D-gluconate:NAD+ 5-oxidoreductase","NAD[c] + 2K3DO_GLCN[c]  <=> H[c] + NADH[c] + DHY_DOHEXNA[c] ","TT_P0037",null,"Pentose Phosphate Pathway","1.1.1.125"]
["R043","D-fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase","F1P[c]  <=> DHAP[c] + GLYALD[c] ","TTC1414",null,"Alternate Carbon Metabolism","4.1.2.13"]
["R044","L-Fuculose-1-phosphate lactaldehyde-lyase","FUCL1P[c]  <=> DHAP[c] + LALD[c] ","TTC1459",null,"Alternate Carbon Metabolism","4.1.2.17"]
["R045","L-lactaldehyde:NAD+ oxidoreductase","LALD[c] + NAD[c] + H2O[c] <=> LAC[c] + NADH[c] + 2 H[c]","TTC0513",null,"Alternate Carbon Metabolism","1.2.1.22"]
["R046","GDP-mannose:3-phosphoglycerate 3-a-D-mannosyltransferase","3PG[c] + GDP_MAN[c]  <=> GDP[c] + MANNPGLYCT[c] ","TTC0588",null,"Alternate Carbon Metabolism","2.4.1.217"]
["R047","alpha-D-mannosyl-3-phosphoglycerate phosphohydrolase","H2O[c] + MANNPGLYCT[c]  <=> Pi[c] + AMANN_GLYCT[c] ","TTC0589",null,"Alternate Carbon Metabolism","3.1.3.70"]
["R048","D-mannose 6-phosphate 1,6-phosphomutase","M6P[c]  <=> MAN1P[c] ","(TTC1630 or TTC0291 or TTC1063)",null,"Alternate Carbon Metabolism","5.4.2.8"]
["R049","GDP:D-mannose-1-phosphate guanylyltransferase","H[c] + GDP[c] + MAN1P[c]  -> Pi[c] + GDP_MAN[c] ","TTC1388",null,"Alternate Carbon Metabolism","2.7.7.22"]
["R050","ATP:D-fructose 6-phosphotransferase","ATP[c] + D_FRU[c]  -> ADP[c] + H[c] + F6P[c] ","TTC0630",null,"Alternate Carbon Metabolism","2.7.1.4"]
["R051","D-mannose-6-phosphate aldose-ketose-isomerase","M6P[c]  <=> F6P[c] ","TTC0980",null,"Alternate Carbon Metabolism","5.3.1.8"]
["R052","ATP:D-galactose 1-phosphotransferase","ATP[c] + D_GAL[c]  <=> ADP[c] + H[c] + GAL1P[c] ","TTC0226",null,"Alternate Carbon Metabolism","2.7.1.6"]
["R053","UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase","GAL1P[c] + UDP_GLU[c]  <=> G1P[c] + UDP_GAL[c] ","TT_P0071",null,"Alternate Carbon Metabolism","2.7.7.12"]
["R054","UDP-glucose 4-epimerase","UDP_GLU[c]  <=> UDP_GAL[c] ","TTC0222",null,"Alternate Carbon Metabolism","5.1.3.2"]
["R055","Galactan galactohydrolase","H2O[c] + GLCTN[c]  <=> 2 D_GAL[c] ","(TT_P0220 or TT_P0222)",null,"Alternate Carbon Metabolism","3.2.1.23"]
["R056","Lactose galactohydrolase","H2O[c] + LACTS[c]  -> D_GLC[c] + D_GAL[c] ","(TT_P0220 or TT_P0222)",null,"Alternate Carbon Metabolism","3.2.1.23"]
["R057","alpha-D-glucose 1,6-phosphomutase","G1P[c]  <=> G6P[c] ","(TTC1630 or TTC0291 or TTC1063)",null,"Alternate Carbon Metabolism","5.4.2.2"]
["R058","Epimelibiose galactohydrolase","H2O[c] + EPMLBIOS[c]  <=> D_GAL[c] + D_MAN[c] ","TT_P0072",null,"Alternate Carbon Metabolism","3.2.1.22"]
["R059","3-O-alpha-D-Galactosyl-1D-myo-inositol galactohydrolase","H2O[c] + AGAL_INS[c]  <=> D_GAL[c] + M_INS[c] ","TT_P0072",null,"Alternate Carbon Metabolism","3.2.1.22"]
["R060","Melibiitol galactohydrolase","H2O[c] + MLBTL[c]  <=> D_GAL[c] + SORB[c] ","TT_P0072",null,"Alternate Carbon Metabolism","3.2.1.22"]
["R061","Galactosylglycerol galactohydrolase","H2O[c] + GALCS_GLYC[c]  <=> D_GAL[c] + GLYCRL[c] ","TT_P0072",null,"Alternate Carbon Metabolism","3.2.1.22"]
["R062","alkaline alpha-galactosidase","H2O[c] + STCYS[c]  <=> D_GAL[c] + RAFF[c] ","TT_P0072",null,"Alternate Carbon Metabolism","3.2.1.22"]
["R063","Manninotriose galactohydrolase","H2O[c] + MANNTRIS[c]  <=> D_GAL[c] + MLBIOS[c] ","TT_P0072",null,"Alternate Carbon Metabolism","3.2.1.22"]
["R064","Raffinose galactohydrolase","H2O[c] + RAFF[c]  <=> D_GAL[c] + SUC[c] ","TT_P0072",null,"Alternate Carbon Metabolism","3.2.1.22"]
["R065","melibiose galactohydrolase","H2O[c] + MLBIOS[c]  <=> D_GLC[c] + D_GAL[c] ","TT_P0072",null,"Alternate Carbon Metabolism","3.2.1.22"]
["R066","sucrose glucohydrolase","H2O[c] + SUC[c]  -> D_GLC[c] + D_FRU[c] ","(TTC0107 or TTC1283 or TT_P0221)",null,"Alternate Carbon Metabolism","3.2.1.20"]
["R067","palatinose glucohydrolase","H2O[c] + PALT[c]  -> D_GLC[c] + D_FRU[c] ","(TTC0107 or TTC1283 or TT_P0221)",null,"Alternate Carbon Metabolism","3.2.1.20"]
["R068","octaprenyl-diphosphate synthase","ct_FARPPi[c] + 5 IPEN_PPi[c] <=> t_PPREPPi[c] + 5 PPi[c]","TTC1291",null,"Cofactor and Prosthetic Group Biosynthesis","2.5.1.90"]
["R069","chorismate lyase","CORM[c]  -> HY_BNZA[c] + PYR[c]",null,null,"Cofactor and Prosthetic Group Biosynthesis","4.1.3.40"]
["R070","Polyisopentenylpyrolinate:4-hydroxybenzoate nonaprenyltransferase","t_PPREPPi[c] + HY_BNZA[c]  <=> PPi[c] + HY_PPREBNZA[c] ","TTC0240 ",null,"Cofactor and Prosthetic Group Biosynthesis","2.5.1.39"]
["R071","4-hydroxy-3-polyprenylbenzoate carboxy-lyase","CO2[c] + PPRENPhOL[c]  <=> HY_PPREBNZA[c] ","TTC1553",null,"Cofactor and Prosthetic Group Biosynthesis","4.1.1.-"]
["R072","polyprenylphenol hydroxylase","PPRENPhOL[c] + NADPH[c] + O2[c] + H[c] -> PBDIOL[c] + NADP[c] + H2O[c]",null,null,"Cofactor and Prosthetic Group Biosynthesis","1.14.13.-"]
["R073","2-polyprenyl-6-hydroxyphenol methylase","PBDIOL[c] + SAM[c] <=> METPPHOL[c] + SAHC[c] + H[c]",null,null,"Cofactor and Prosthetic Group Biosynthesis","2.1.1.222"]
["R074","2-methoxy-6-all-trans-polyprenylphenol hydroxylase","METPPHOL[c] + H[c] + NADPH[c] + O2[c] -> PPRE_MOX_BNZQ[c] + NADP[c] + H2O[c]",null,null,"Cofactor and Prosthetic Group Biosynthesis","1.14.13.-"]
["R075","2-Polyprenyl-6-methoxy-1,4-benzoquinone hydroxylase","PPRE_MOX_BNZQ[c] + NADPH[c] + O2[c] -> DEMQH2[c] + NADP[c] + H2O[c]",null,null,"Cofactor and Prosthetic Group Biosynthesis","1.14.13.-"]
["R076","3-Demethylubiquinol methylase","DEMQH2[c] + SAM[c] -> QH2[c] + SAHC[c] + H[c]",null,null,"Cofactor and Prosthetic Group Biosynthesis","2.1.1.64"]
["R077","ubiquinone/menaquinone biosynthesis methyltransferase","PPRE_MOX_BNZQ[c] + SAM[c]  <=> PPRE_MMOX_BNZQ[c] + SAHC[c] ","TTC1503",null,"Cofactor and Prosthetic Group Biosynthesis","2.1.1.201"]
["R078","2-Polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase","PPRE_MMOX_BNZQ[c] + NADPH[c] + O2[c] -> DMMQ[c] + NADP[c] + H2O[c]",null,null,"Cofactor and Prosthetic Group Biosynthesis","1.14.13.-"]
["R079","S-adenosyl-L-methione:demethylmenaquinone methyltransferase","SAM[c] + DMMQ[c]  <=> SAHC[c] + MQ[c] ","TTC1503",null,"Cofactor and Prosthetic Group Biosynthesis","2.1.1.163"]
["R080","(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate hydrolyase (2-succinylbenzoate-forming)","HY_SUCC_CYCHEXDE_CARBA[c]  -> H2O[c] + SUCC_BNZA[c] ","TTC0519",null,"Cofactor and Prosthetic Group Biosynthesis","4.2.1.113"]
["R081","Acetyl-CoA:carbon-dioxide ligase (ADP-forming)","ACoA[c] + CBTN_CCP[c]  <=> MALCoA[c] + HCARB[c] ","(TTC0758 and TTC1408 and TTC1409)",null,"Cell Envelope Biosynthesis","6.4.1.2"]
["R082","glutaryl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase (decarboxylating)","H[c] + FAD[c] + GLUTRCoA[c]  -> CO2[c] + FADH2[c] + CROCoA[c] ","TTC0435",null,"Membrane Lipid Metabolism","1.3.8.6"]
["R083","NADH:ubiquinone oxidoreductase","4 H[c] + NADH[c] + MQ[c]  -> NAD[c] + MQL[c] + 3 H[e] ","(TTC1907 and TTC1908 and TTC1909 and TTC1910 and TTC1911 and TTC1912 and TTC1913 and TTC1914 and TTC1915 and TTC1916 and TTC1917 and TTC1918 and TTC1919 and TTC1920 and TT_P0054)",null,"Oxidative Phosphorylation","1.6.5.3"]
["R084","Ubiquinol:ferricytochrome-c oxidoreductase","MQL[c] + 2 CYT_C3[c]  <=> MQ[c] + 2 CYT_C2[c] ",null,null,"Oxidative Phosphorylation","1.10.2.2"]
["R085","diphosphate phosphohydrolase","PPi[c] + H2O[c]  -> 2 Pi[c] + H[c] ","TTC1600",null,"Anaplerotic Reactions","3.6.1.1"]
["R086","ATP phosphohydrolase","ATP[c] + H2O[c]  -> ADP[c] + Pi[c] + H[c] ","(TT_P0081 or TT_P0211 or TTC1823 or TTC1844 or TTC1290)",null,"Nucleotide Salvage Pathway","3.6.3.14"]
["R087","ADP-ribose ribophosphohydrolase","H2O[c] + ADP_RIB[c]  -> 2 H[c] + AMP[c] + R5P[c] ","(TTC0160 or TTC0511)",null,"Nucleotide Salvage Pathway","3.6.1.13"]
["R088","5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating)","L_GLN[c] + H2O[c] + PRPP[c]  -> L_GLU[c] + PPi[c] + PRIBSAMN[c] ","TTC1156",null,"Nucleotide Salvage Pathway","2.4.2.14"]
["R089","5-Phospho-D-ribosylamine:glycine ligase (ADP-forming)","L_GLY[c] + ATP[c] + PRIBSAMN[c]  -> ADP[c] + Pi[c] + H[c] + GAR[c] ","TTC0460",null,"Nucleotide Salvage Pathway","6.3.4.13"]
["R090","5'-Phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)","L_GLN[c] + ATP[c] + H2O[c] + FGAR[c]  -> L_GLU[c] + ADP[c] + Pi[c] + H[c] + FGAM[c] ","(TTC1152 or TTC1153 or TTC1155 or TTC1383)",null,"Nucleotide Salvage Pathway","6.3.5.3"]
["R091","2-(Formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)","ATP[c] + FGAM[c]  -> ADP[c] + Pi[c] + 2 H[c] + AIR[c] ","TTC1619",null,"Nucleotide Salvage Pathway","6.3.3.1"]
["R092","5-amino-1-(5-phospho-D-ribosyl)imidazole:carbon-dioxide ligase (ADP-forming)","ATP[c] + AIR[c] + HCO3[c]  -> ADP[c] + Pi[c] + H[c] + 5CAIZ[c] ","TTC0137",null,"Nucleotide Salvage Pathway","6.3.4.18"]
["R093","5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole carboxymutase","5CAIZ[c]  <=> CAIR[c] ","TTC0138",null,"Nucleotide Salvage Pathway","5.4.99.18"]
["R094","1-(5-Phosphoribosyl)-5-amino-4-carboxyimidazole:L-aspartate ligase (ADP-forming)","L_ASP[c] + ATP[c] + CAIR[c]  <=> ADP[c] + Pi[c] + H[c] + SAICAR[c] ","TTC1151",null,"Nucleotide Salvage Pathway","6.3.2.6"]
["R095","1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole AMP-lyase","SAICAR[c]  <=> FUM[c] + AICAR[c] ","TTC1149",null,"Nucleotide Salvage Pathway","4.3.2.2"]
["R096","1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide:pyrophosphate phosphoribosyltransferase","PPi[c] + AICAR[c]  <=> PRPP[c] + 5A_4IMDZCARBA[c] ","(TTC1249 or TTC1250)",null,"Nucleotide Salvage Pathway","2.4.2.7"]
["R097","10-Formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase","AICAR[c] + 10F_THF[c]  <=> THF[c] + FAICAR[c] ","TTC0561",null,"Nucleotide Salvage Pathway","2.1.2.3"]
["R098","IMP 1,2-hydrolase (decyclizing)","H2O[c] + IMP[c]  <=> FAICAR[c] ","TTC0561",null,"Nucleotide Salvage Pathway","3.5.4.10"]
["R099","P1,P4-bis(5'-adenosyl)-tetraphosphate adenylohydrolase","H2O[c] + BADNS_PPP[c]  -> ATP[c] + AMP[c] ","(TTC1519 or TTC1859)",null,"Nucleotide Salvage Pathway","3.6.1.17"]
["R100","ATP:sulfate adenylyltransferase","ATP[c] + H[c] + SO4[c]  -> PPi[c] + APS[c] ","TTC0307",null,"Nucleotide Salvage Pathway","2.7.7.4"]
["R101","ATP:dIDP phosphotransferase","ATP[c] + dIDP[c]  <=> ADP[c] + dITP[c] ","TTC1798",null,"Nucleotide Salvage Pathway","2.7.4.6"]
["R102","2'-Deoxyinosine-5'-triphosphate pyrophosphohydrolase","H2O[c] + dITP[c]  -> PPi[c] + H[c] + dIMP[c] ","(TTC1290 or TTC1583)",null,"Nucleotide Salvage Pathway","3.6.1.19"]
["R103","guanosine 3'-diphosphate 5'-triphosphate 5'-phosphohydrolase","H2O[c] + GUNS_3PPi_5TPi[c]  -> Pi[c] + H[c] + GUNSBP[c] ","TTC0636",null,"Nucleotide Salvage Pathway","3.6.1.40"]
["R104","P1,P4-bis(5'-guanosyl)-tetraphosphate guanylylhydrolase","GTP[c] + GMP[c]  -> H2O[c] + 2 H[c] + BGUNS_PPP[c] ","(TTC1519 or TTC1859)",null,"Nucleotide Salvage Pathway","3.6.1.17"]
["R105","dGTP triphosphohydrolase","dGTP[c] + H2O[c]  -> dGUNS[c] + TPi[c] ","TTC0044",null,"Nucleotide Salvage Pathway","3.1.5.1"]
["R106","guanosine-3',5'-bis(diphosphate) 3'-diphosphohydrolase","H2O[c] + GUNSBP[c]  -> PPi[c] + GDP[c] ","TTC1355",null,"Nucleotide Salvage Pathway","3.1.7.2"]
["R107","ATP:GDP phosphotransferase","ATP[c] + GDP[c]  -> GTP[c] + ADP[c] ","TTC1798",null,"Nucleotide Salvage Pathway","2.7.4.6"]
["R108","ATP:dGDP phosphotransferase","ATP[c] + dGDP[c]  <=> dGTP[c] + ADP[c] ","TTC1798",null,"Nucleotide Salvage Pathway","2.7.4.6"]
["R109","dGTP:pyruvate 2-O-phosphotransferase","PEP[c] + dGDP[c]  -> dGTP[c] + PYR[c] ","TTC1611",null,"Nucleotide Salvage Pathway","2.7.1.40"]
["R110","2'-Deoxyguanosine 5'-triphosphate diphosphohydrolase","dGTP[c] + H2O[c]  -> PPi[c] + H[c] + dGMP[c] ","(TTC1290 or TTC1583)",null,"Nucleotide Salvage Pathway","3.6.1.19"]
["R111","2'-Deoxyguanosine 5'-monophosphate phosphohydrolase","H2O[c] + dGMP[c]  -> Pi[c] + dGUNS[c] ","(TTC0964 or TTC1625 or TT_P0028)",null,"Nucleotide Salvage Pathway","3.1.3.5"]
["R112","2'-Deoxyguanosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase","GDP[c] + R_TRED[c]  -> H2O[c] + dGDP[c] + O_TRED[c] ","(TTC1930 and TT_P0161 and TT_P0162)",null,"Nucleotide Salvage Pathway","1.17.4.1"]
["R113","ATP:dGMP phosphotransferase","ATP[c] + dGMP[c]  <=> ADP[c] + dGDP[c] ","TTC1197",null,"Nucleotide Salvage Pathway","2.7.4.8"]
["R114","Deoxyguanosine:orthophosphate ribosyltransferase","Pi[c] + dGUNS[c]  <=> dR1P[c] + GUN[c] ","((TTC0194 or TTC1070) or TTC1412)",null,"Nucleotide Salvage Pathway","2.4.2.1 or 2.4.2.4"]
["R115","GTP diphosphohydrolase (diphosphate-forming)","GTP[c] + H2O[c]  -> PPi[c] + H[c] + GMP[c] ","(TTC1290 or TTC1583)",null,"Nucleotide Salvage Pathway","3.6.1.19"]
["R116","ATP:GMP phosphotransferase","ATP[c] + GMP[c]  <=> ADP[c] + GDP[c] ","TTC1197",null,"Nucleotide Salvage Pathway","2.7.4.8"]
["R117","Guanosine 5'-monophosphate phosphohydrolase","H2O[c] + GMP[c]  -> Pi[c] + GUNS[c] ","(TTC0964 or TTC1625 or TT_P0028)",null,"Nucleotide Salvage Pathway","3.1.3.5"]
["R118","guanosine:phosphate alpha-D-ribosyltransferase","Pi[c] + GUNS[c]  <=> R1P[c] + GUN[c] ","(TTC0194 or TTC1070)",null,"Nucleotide Salvage Pathway","2.4.2.1"]
["R119","GMP:diphosphate 5-phospho-alpha-D-ribosyltransferase","PRPP[c] + GUN[c]  <=> PPi[c] + GMP[c] ","((TTC1249 or TTC1250) or TTC1766)",null,"Nucleotide Salvage Pathway","2.4.2.7 or 2.4.2.8"]
["R120","Xanthosine-5'-phosphate:ammonia ligase (AMP-forming)","ATP[c] + XMP[c] + NH4[c]  -> PPi[c] + 2 H[c] + AMP[c] + GMP[c] ","TTC1187",null,"Nucleotide Salvage Pathway","6.3.5.2"]
["R121","P1,P4-Bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase","H2O[c] + XppppX[c]  -> XMP[c] + XTP[c] ","(TTC1519 or TTC1859)",null,"Nucleotide Salvage Pathway","3.6.1.17"]
["R122","Inosine 5'-triphosphate pyrophosphohydrolase","H2O[c] + ITP[c]  -> PPi[c] + H[c] + IMP[c] ","(TTC1290 or TTC1583)",null,"Nucleotide Salvage Pathway","3.6.1.19"]
["R123","ATP:IDP phosphotransferase","ATP[c] + IDP[c]  <=> ADP[c] + ITP[c] ","TTC1798",null,"Nucleotide Salvage Pathway","2.7.4.6"]
["R124","XTP pyrophosphohydrolase","H2O[c] + XTP[c]  -> PPi[c] + H[c] + XMP[c] ","(TTC1290 or TTC1583)",null,"Nucleotide Salvage Pathway","3.6.1.19"]
["R125","Xanthosine 5'-phosphate phosphohydrolase","H2O[c] + XMP[c]  -> Pi[c] + XNTHS[c] ","(TTC0964 or TTC1625 or TT_P0028)",null,"Nucleotide Salvage Pathway","3.1.3.5"]
["R126","XMP:pyrophosphate phosphoribosyltransferase","PRPP[c] + XTHN[c]  -> PPi[c] + XMP[c] ","TTC1766",null,"Nucleotide Salvage Pathway","2.4.2.22 or 2.4.2.8"]
["R127","Xanthosine:orthophosphate ribosyltransferase","Pi[c] + XNTHS[c]  <=> R1P[c] + XTHN[c] ","(TTC0194 or TTC1070)",null,"Nucleotide Salvage Pathway","2.4.2.1"]
["R128","IMP:NAD+ oxidoreductase","NAD[c] + H2O[c] + IMP[c]  -> H[c] + NADH[c] + XMP[c] ","(TTC0064 or TTC1634)",null,"Nucleotide Salvage Pathway","1.1.1.205"]
["R129","IMP:diphosphate phospho-D-ribosyltransferase","PRPP[c] + HXTHN[c]  <=> PPi[c] + IMP[c] ","TTC1766",null,"Nucleotide Salvage Pathway","2.4.2.8"]
["R130","Inosine 5'-monophosphate phosphohydrolase","H2O[c] + IMP[c]  -> Pi[c] + INSN[c] ","(TTC0964 or TTC1625 or TT_P0028)",null,"Nucleotide Salvage Pathway","3.1.3.5"]
["R131","inosine:phosphate alpha-D-ribosyltransferase","Pi[c] + INSN[c]  <=> R1P[c] + HXTHN[c] ","(TTC0194 or TTC1070)",null,"Nucleotide Salvage Pathway","2.4.2.1"]
["R132","IMP:L-aspartate ligase (GDP-forming)","L_ASP[c] + GTP[c] + IMP[c]  -> Pi[c] + 2 H[c] + GDP[c] + ADN_SUCC[c] ","TTC1764",null,"Nucleotide Salvage Pathway","6.3.4.4"]
["R133","N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming)","ADN_SUCC[c]  -> AMP[c] + FUM[c] ","TTC1149",null,"Nucleotide Salvage Pathway","4.3.2.2"]
["R134","Adenosine 5'-monophosphate phosphohydrolase","H2O[c] + AMP[c]  -> Pi[c] + ADSN[c] ","(TTC0964 or TTC1625 or TT_P0028)",null,"Nucleotide Salvage Pathway","3.1.3.5"]
["R135","Adenosine:phosphate alpha-D-ribosyltransferase","Pi[c] + ADSN[c]  <=> R1P[c] + ADN[c] ","(TTC0194 or TTC1070)",null,"Nucleotide Salvage Pathway","2.4.2.1"]
["R136","Deoxyinosine:orthophosphate ribosyltransferase","Pi[c] + zCARO[c]  -> dR1P[c] + HXTHN[c] ","((TTC0194 or TTC1070) or TTC1412)",null,"Nucleotide Salvage Pathway","2.4.2.1 or 2.4.2.4"]
["R137","Deoxyadenosine:orthophosphate ribosyltransferase","Pi[c] + dADS[c]  <=> dR1P[c] + ADN[c] ","(TTC0194 or TTC1070)",null,"Nucleotide Salvage Pathway","2.4.2.1"]
["R138","ATP:ADP phosphatransferase","ATP[c] + ADP[c]  <=> ATP[c] + ADP[c] ","TTC1798",null,"Nucleotide Salvage Pathway","2.7.4.6"]
["R139","ATP:AMP phosphotransferase","ATP[c] + AMP[c]  -> 2 ADP[c] ","TTC1307",null,"Nucleotide Salvage Pathway","2.7.4.3"]
["R140","2'-Deoxyadenosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase","ADP[c] + R_TRED[c]  <=> H2O[c] + O_TRED[c] + dADP[c] ","(TTC1930 and TT_P0161 and TT_P0162)",null,"Nucleotide Salvage Pathway","1.17.4.1"]
["R141","ATP:dADP phosphotransferase","ATP[c] + dADP[c]  -> dATP[c] + ADP[c] ","TTC1798",null,"Nucleotide Salvage Pathway","2.7.4.6"]
["R142","ATP:dAMP phosphotransferase","ATP[c] + dAMP[c]  <=> ADP[c] + dADP[c] ","TTC1307",null,"Nucleotide Salvage Pathway","2.7.4.3"]
["R143","2'-Deoxyadenosine 5'-monophosphate phosphohydrolase","H2O[c] + dAMP[c]  <=> Pi[c] + dADS[c] ","(TTC0964 or TTC1625 or TT_P0028)",null,"Nucleotide Salvage Pathway","3.1.3.5"]
["R144","carbamoyl-phosphate:L-aspartate carbamoyltransferase","L_ASP[c] + CARB_Pi[c]  -> Pi[c] + H[c] + CARB_ASP[c] ","TTC0427",null,"Nucleotide Salvage Pathway","2.1.3.2"]
["R145","hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating)","L_GLN[c] + 2 ATP[c] + H2O[c] + HCO3[c]  -> L_GLU[c] + 2 ADP[c] + Pi[c] + 2 H[c] + CARB_Pi[c] ","(TTC0247 and TTC1706)",null,"Nucleotide Salvage Pathway","6.3.5.5"]
["R146","(S)-dihydroorotate amidohydrolase","H2O[c] + DHY_ORTA[c]  <=> H[c] + CARB_ASP[c] ","TTC0426",null,"Nucleotide Salvage Pathway","3.5.2.3"]
["R147","CTP aminohydrolase","CTP[c] + H2O[c]  -> UTP[c] + NH4[c] ","TTC1864",null,"Nucleotide Salvage Pathway","3.5.4.13"]
["R148","NADPH:oxidized-thioredoxin oxidoreductase","H[c] + NADPH[c] + O_TRED[c]  -> NADP[c] + R_TRED[c] ","(TTC0096 or TTC0853 or TTC1555)",null,"Oxidative Phosphorylation","1.8.1.9"]
["R149","UTP:ammonia ligase (ADP-forming)","L_GLN[c] + ATP[c] + UTP[c] + H2O[c]  -> L_GLU[c] + CTP[c] + ADP[c] + Pi[c] + 2 H[c] ","TTC1102",null,"Nucleotide Salvage Pathway","6.3.4.2"]
["R150",null,"L_GLN[c] + ATP[c] + UTP[c] + H2O[c]  -> L_GLU[c] + PPi[c] + 2 H[c] + AMP[c] + GMP[c] ",null,null,"Nucleotide Salvage Pathway"]
["R151","dCTP aminohydrolase","dCTP[c] + H2O[c] + H[c]  -> NH4[c] + dUTP[c] ","TTC1864",null,"Nucleotide Salvage Pathway","3.5.4.13"]
["R152","Orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase","PPi[c] + ORTD5P[c]  <=> PRPP[c] + ORTA[c] ","TTC1380",null,"Nucleotide Salvage Pathway","2.4.2.10"]
["R153","P1,P4-bis(5'-uridyl)-tetraphosphate uridylohydrolase","H2O[c] + UppppU[c]  -> UTP[c] + UMP[c] ","(TTC1519 or TTC1859)",null,"Nucleotide Salvage Pathway","3.6.1.17"]
["R154","ATP:UDP phosphotransferase","ATP[c] + UDP[c]  <=> UTP[c] + ADP[c] ","TTC1798",null,"Nucleotide Salvage Pathway","2.7.4.6"]
["R155","ATP:CDP phosphotransferase","ATP[c] + CDP[c]  <=> CTP[c] + ADP[c] ","TTC1798",null,"Nucleotide Salvage Pathway","2.7.4.6"]
["R156","ATP:dCDP phosphotransferase","ATP[c] + dCDP[c]  <=> dCTP[c] + ADP[c] ","TTC1798",null,"Nucleotide Salvage Pathway","2.7.4.6"]
["R157","ATP:dUDP phosphotransferase","ATP[c] + dUDP[c]  <=> ADP[c] + dUTP[c] ","TTC1798",null,"Nucleotide Salvage Pathway","2.7.4.6"]
["R158","ATP:dTDP phosphotransferase","ATP[c] + dTDP[c]  <=> dTTP[c] + ADP[c] ","TTC1798",null,"Nucleotide Salvage Pathway","2.7.4.6"]
["R159","Uridine triphosphate pyrophosphohydrolase","UTP[c] + 2 H2O[c]  -> 2 Pi[c] + 2 H[c] + UMP[c] ","(TTC1290 or TTC1583)",null,"Nucleotide Salvage Pathway","3.6.1.19"]
["R160","dUTP nucleotidohydrolase","H2O[c] + dUTP[c]  -> PPi[c] + H[c] + dUMP[c] ","(TTC1290 or TTC1583)",null,"Nucleotide Salvage Pathway","3.6.1.19"]
["R161","2'-Deoxycytidine diphosphate:oxidized-thioredoxin 2'-oxidoreductase","R_TRED[c] + CDP[c]  -> H2O[c] + O_TRED[c] + dCDP[c] ","(TTC1930 and TT_P0161 and TT_P0162)",null,"Nucleotide Salvage Pathway","1.17.4.1"]
["R162","2'-Deoxyuridine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase","R_TRED[c] + UDP[c]  -> H2O[c] + O_TRED[c] + dUDP[c] ","(TTC1930 and TT_P0161 and TT_P0162)",null,"Nucleotide Salvage Pathway","1.17.4.1"]
["R163","orotidine-5'-phosphate carboxy-lyase (UMP-forming)","H[c] + ORTD5P[c]  -> CO2[c] + UMP[c] ","TTC1381",null,"Nucleotide Salvage Pathway","4.1.1.23"]
["R164","ATP:UMP phosphotransferase","ATP[c] + UMP[c]  <=> ADP[c] + UDP[c] ","(TTC0089 or TTC0507)",null,"Nucleotide Salvage Pathway","2.7.4.14 or 2.7.4.22"]
["R165","ATP:CMP phosphotransferase","ATP[c] + CMP[c]  <=> ADP[c] + CDP[c] ","TTC0089",null,"Nucleotide Salvage Pathway","2.7.4.14"]
["R166","ATP:dCMP phosphotransferase","ATP[c] + dCMP[c]  <=> ADP[c] + dCDP[c] ","TTC0089",null,"Nucleotide Salvage Pathway","2.7.4.15"]
["R167","ATP:dUMP phosphotransferase","ATP[c] + dUMP[c]  <=> ADP[c] + dUDP[c] ","TTC1243",null,"Nucleotide Salvage Pathway","2.7.4.9"]
["R168","ATP:dTMP phosphotransferase","ATP[c] + dTMP[c]  <=> ADP[c] + dTDP[c] ","TTC1243",null,"Nucleotide Salvage Pathway","2.7.4.9"]
["R169","ATP:uridine 5'-phosphotransferase","ATP[c] + URD[c]  <=> ADP[c] + H[c] + UMP[c] ","TTC0210",null,"Nucleotide Salvage Pathway","2.7.1.48"]
["R170","ATP:cytidine 5'-phosphotransferase","ATP[c] + CYTD[c]  -> ADP[c] + H[c] + CMP[c] ","TTC0210",null,"Nucleotide Salvage Pathway","2.7.1.48"]
["R171","GTP:cytidine 5'-phosphotransferase","GTP[c] + CYTD[c]  -> H[c] + GDP[c] + CMP[c] ","TTC0210",null,"Nucleotide Salvage Pathway","2.7.1.48"]
["R172","guanosine nucleotides de novo biosynthesis","GTP[c] + FMN[c]  -> dGTP[c] + H2O[c] + FMNH2[c] ",null,null,"Nucleotide Salvage Pathway"]
["R173","UTP:uridine 5'-phosphotransferase","UTP[c] + URD[c]  -> UMP[c] + UDP[c] ","TTC0210",null,"Nucleotide Salvage Pathway","2.7.1.48"]
["R174","GTP:uridine 5'-phosphotransferase","GTP[c] + URD[c]  -> H[c] + GDP[c] + UMP[c] ","TTC0210",null,"Nucleotide Salvage Pathway","2.7.1.48"]
["R175","ITP:uridine 5'-phosphotransferase","ITP[c] + URD[c]  -> IDP[c] + UMP[c] ","TTC0210",null,"Nucleotide Salvage Pathway","2.7.1.48"]
["R176","dGTP:uridine 5'-phosphotransferase","dGTP[c] + URD[c]  -> dGDP[c] + UMP[c] ","TTC0210",null,"Nucleotide Salvage Pathway","2.7.1.48"]
["R177","dTTP:uridine 5'-phosphotransferase","dTTP[c] + URD[c]  -> UMP[c] + dTDP[c] ","TTC0210",null,"Nucleotide Salvage Pathway","2.7.1.48"]
["R178","dCTP:uridine 5'-phosphotransferase","dCTP[c] + URD[c]  -> UMP[c] + dCDP[c] ","TTC0210",null,"Nucleotide Salvage Pathway","2.7.1.48"]
["R179","dUTP:uridine 5'-phosphotransferase","dUTP[c] + URD[c]  -> UMP[c] + dUDP[c] ","TTC0210",null,"Nucleotide Salvage Pathway","2.7.1.48"]
["R180","Uridine 5'-monophosphate phosphohydrolase","H2O[c] + UMP[c]  -> Pi[c] + URD[c] ","(TTC0964 or TTC1625 or TT_P0028)",null,"Nucleotide Salvage Pathway","3.1.3.5"]
["R181","Thymidylate 5'-phosphohydrolase","H2O[c] + dTMP[c]  -> Pi[c] + THYMD[c] ","(TTC0964 or TTC1625 or TT_P0028)",null,"Nucleotide Salvage Pathway","3.1.3.5"]
["R182","2'-Deoxycytidine 5'-monophosphate phosphohydrolase","H2O[c] + dCMP[c]  -> Pi[c] + dCYTD[c] ","(TTC0964 or TTC1625 or TT_P0028)",null,"Nucleotide Salvage Pathway","3.1.3.5"]
["R183","UMP:diphosphate phospho-alpha-D-ribosyltransferase","PPi[c] + UMP[c]  <=> PRPP[c] + URA[c] ","(TTC0428 or TTC0946)",null,"Nucleotide Salvage Pathway","2.4.2.9"]
["R184","Cytidine aminohydrolase","H2O[c] + H[c] + CYTD[c]  <=> NH4[c] + URD[c] ","TTC0383",null,"Nucleotide Salvage Pathway","3.5.4.5"]
["R185","Deoxycytidine aminohydrolase","H2O[c] + H[c] + dCYTD[c]  -> NH4[c] + dURD[c] ","TTC0383",null,"Nucleotide Salvage Pathway","3.5.4.5"]
["R186","5,10-methylenetetrahydrofolate,NADPH:dUMP C-methyltransferase","NADPH[c] + dUMP[c] + 5_10_MNTHF[c]  -> NADP[c] + THF[c] + dTMP[c] ","TTC0731",null,"Nucleotide Salvage Pathway","2.1.1.148"]
["R187","deoxyuridine:orthophosphate 2-deoxy-D-ribosyltransferase","Pi[c] + dURD[c]  -> dR1P[c] + URA[c] ","((TTC0194 or TTC1070) or TTC1412)",null,"Nucleotide Salvage Pathway","2.4.2.1 or 2.4.2.4"]
["R188","thymidine:phosphate deoxy-alpha-D-ribosyltransferase","Pi[c] + THYMD[c]  <=> dR1P[c] + THYM[c] ","TTC1412",null,"Nucleotide Salvage Pathway","2.4.2.4"]
["R189","dihydropyrimidine dehydrogenase","THYM[c] + NADPH[c] + H[c] -> DHTHYM[c] + NADP[c]",null,null,"Nucleotide Salvage Pathway","1.3.1.2"]
["R190","dihydropyrimidinase","DHTHYM[c] + H2O[c] -> H[c] + UREIDO_BUTR[c]","TTC0426",null,"Nucleotide Salvage Pathway","3.5.2.2"]
["R191","3-Ureidoisobutyrate amidohydrolase","H2O[c] + UREIDO_BUTR[c]  -> CO2[c] + NH4[c] + 3AIBUTNA[c] ","TTC1539",null,"Nucleotide Salvage Pathway","3.5.1.6"]
["R192","L-Alanine:NAD+ oxidoreductase (deaminating)","H[c] + NADH[c] + PYR[c] + NH4[c]  <=> L_ALA[c] + NAD[c] + H2O[c] ","(TTC1082 or TTC1770)","ald","Alanine and Aspartate Metabolism","1.4.1.1"]
["R193","L-Alanine:glyoxylate aminotransferase","L_ALA[c] + GLOXT[c]  -> L_GLY[c] + PYR[c] ","TTC1813",null,"Alanine and Aspartate Metabolism","2.6.1.44"]
["R194","L-Citrulline:L-aspartate ligase (AMP-forming)","L_ASP[c] + ATP[c] + CTRLN[c]  <=> PPi[c] + H[c] + AMP[c] + L_ARG_SUCC[c] ","TTC1701","argG","Arginine and Proline Metabolism","6.3.4.5"]
["R195","2-(Nomega-L-arginino)succinate arginine-lyase (fumarate-forming)","L_ARG_SUCC[c]  -> L_ARG[c] + FUM[c] ","TTC1702","argH","Arginine and Proline Metabolism","4.3.2.1"]
["R196","L-aspartate:ammonia ligase (AMP-forming)","L_ASP[c] + ATP[c] + NH4[c]  <=> L_ASN[c] + PPi[c] + H[c] + AMP[c] ","TTC0282","asnA","Alanine and Aspartate Metabolism","6.3.5.4"]
["R197","L-asparginase","L_ASN[c] + H2O[c]  -> L_ASP[c] + NH4[c] + H[c]","TTC1938",null,"Alanine and Aspartate Metabolism","3.5.1.1"]
["R198","L-Aspartate:2-oxoglutarate aminotransferase","L_ASP[c] + AKG[c]  <=> L_GLU[c] + OAC[c] ","(TTC1960 or TTC1641)","aspC","Alanine and Aspartate Metabolism","2.6.1.1"]
["R199","Succinate-semialdehyde:NADP+ oxidoreductase","NADP[c] + H2O[c] + SUCC_SA[c]  -> 2 H[c] + NADPH[c] + SUCC[c] ","TTC0634",null,"Arginine and Proline Metabolism","1.2.1.16"]
["R200","4-aminobutanoate:2-oxoglutarate aminotransferase","AKG[c] + 4ABUT[c]  -> L_GLU[c] + SUCC_SA[c] ","TTC0510",null,"Arginine and Proline Metabolism","2.6.1.19"]
["R201","L-glutamate:NAD+ oxidoreductase (deaminating)","L_GLU[c] + NAD[c] + H2O[c]  <=> H[c] + NADH[c] + AKG[c] + NH4[c] ","(TTC1211 or TTC1212)","gdh","Glutamate Metabolism","1.4.1.3"]
["R202","L-Glutamate:NADP+ oxidoreductase (deaminating)","L_GLU[c] + NADP[c] + H2O[c]  <=> H[c] + NADPH[c] + AKG[c] + NH4[c] ","(TTC1104 or (TTC1211 or TTC1212))","gdh","Glutamate Metabolism","(1.4.1.13 or 1.4.1.14)"]
["R203","L-Glutamate:NADP+ oxidoreductase (transaminating)","L_GLN[c] + H[c] + NADPH[c] + AKG[c]  -> 2 L_GLU[c] + NADP[c] ","TTC1104",null,"Glutamate Metabolism ","1.4.1.13"]
["R204","(S)-1-pyrroline-5-carboxylate:NAD+ oxidoreductase","NAD[c] + 2 H2O[c] + PYRR5CARB[c]  -> L_GLU[c] + H[c] + NADH[c] ","TTC1213",null,"Arginine and Proline Metabolism","1.5.1.12"]
["R205","L-Glutamate:ammonia ligase (ADP-forming)","L_GLU[c] + ATP[c] + NH4[c]  -> L_GLN[c] + ADP[c] + Pi[c] + H[c] ","TTC0965","gln","Glutamate Metabolism ","6.3.1.2"]
["R206","L-glutamine:D-fructose-6-phosphate isomerase (deaminating)","L_GLN[c] + F6P[c]  -> L_GLU[c] + GLUSAP[c] ","TTC1533",null,"Glutamate Metabolism ","2.6.1.16"]
["R207","D-Glycerate:NAD+ 2-oxidoreductase","H[c] + NADH[c] + HY_PYR[c]  -> NAD[c] + D_GLCT[c] ","(TTC0431 or TTC0124)",null,"Alternate Carbon Metabolism","(1.1.1.26 or 1.1.1.81)"]
["R208","D-Glycerate:NADP+ 2-oxidoreductase","H[c] + NADPH[c] + HY_PYR[c]  -> NADP[c] + D_GLCT[c] ","TTC0124",null,"Alternate Carbon Metabolism","1.1.1.81"]
["R209","L-Serine:pyruvate aminotransferase","L_SER[c] + PYR[c]  -> L_ALA[c] + HY_PYR[c] ","TTC1813",null,"Glycine and Serine Metabolism","2.6.1.51"]
["R210","3-Phospho-D-glycerate:NAD+ 2-oxidoreductase","NAD[c] + 3PG[c]  -> H[c] + NADH[c] + 3POXPYR[c] ","(TTC0586 or TTC1209)","serA","Glycine and Serine Metabolism","1.1.1.95"]
["R211","L-serine ammonia-lyase","L_SER[c]  -> PYR[c] + NH4[c] ","((TTC0387 or TTC0667) or TTC1708)",null,"Glycine and Serine Metabolism","(4.3.1.17 or 4.3.1.19)"]
["R212","L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate","L_SER[c] + IND_GLYP[c]  <=> L_TRP[c] + H2O[c] + GAP[c] ","(TTC0729 and TTC0730)","trpA","Tyrosine, Tryptophan, and Phenylalanine Metabolism","4.2.1.20"]
["R213","5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase","L_GLY[c] + H2O[c] + 5_10_MNTHF[c]  <=> L_SER[c] + THF[c] ","TTC1160","glyA","Glycine and Serine Metabolism","2.1.2.1"]
["R214","glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating)","L_GLY[c] + LPP[c]  -> CO2[c] + AMDHY_LPP[c] ","(TTC0150 or TTC0151)",null,"Glycine and Serine Metabolism","1.4.4.2"]
["R215","S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming)","THF[c] + AMDHY_LPP[c]  -> NH4[c] + 5_10_MNTHF[c] + DHY_LPP[c] ","TTC0148",null,"Glycine and Serine Metabolism","2.1.2.10"]
["R216","dihydrolipoylprotein:NAD+ oxidoreductase","NAD[c] + DHY_LPP[c]  -> H[c] + NADH[c] + LPP[c] ","(TTC1700 or TTC1753)",null,"Glycine and Serine Metabolism","1.8.1.4"]
["R217","L-threonine acetaldehyde-lyase (glycine-forming)","L_THR[c]  -> L_GLY[c] + AALD[c] ","TTC0397",null,"Threonine and Lysine Metabolism","4.1.2.5"]
["R218","Acetyl-CoA:glycine C-acetyltransferase","CoA[c] + A_OXBUT[c]  <=> L_GLY[c] + ACoA[c] ","TTC1219",null,"Glycine and Serine Metabolism","2.3.1.29"]
["R219","L-threonine:NAD+ oxidoreductase","L_THR[c] + NAD[c]  -> H[c] + NADH[c] + A_OXBUT[c] ","TTC0201",null,"Glycine and Serine Metabolism","1.1.1.103"]
["R220","L-threonine ammonia-lyase (2-oxobutanoate-forming)","L_THR[c]  -> NH4[c] + AKB[c] ","TTC1708","ilvA","Threonine and Lysine Metabolism","4.3.1.19"]
["R221","O-phospho-L-homoserine phosphate-lyase (adding water;L-threonine-forming)","H2O[c] + OP_HSER[c]  -> L_THR[c] + Pi[c] ","TTC0117","thrC","Threonine and Lysine Metabolism","4.2.3.1"]
["R222","ATP:L-homoserine O-phosphotransferase","ATP[c] + L_HSER[c]  -> ADP[c] + H[c] + OP_HSER[c] ","TTC1028","thrB","Threonine and Lysine Metabolism","2.7.1.39"]
["R223","L-Homoserine:NAD+ oxidoreductase","H[c] + NADH[c] + ASP_4SA[c]  -> NAD[c] + L_HSER[c] ","TTC0115","thrA","Threonine and Lysine Metabolism","1.1.1.3"]
["R224","L-homoserine:NADP+ oxidoreductase","H[c] + NADPH[c] + ASP_4SA[c]  -> NADP[c] + L_HSER[c] ","TTC0115","thrA","Threonine and Lysine Metabolism","1.1.1.3"]
["R225","L-Aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating)","H[c] + NADPH[c] + 4P_ASP[c]  <=> NADP[c] + Pi[c] + ASP_4SA[c] ","TTC0177","asd","Threonine and Lysine Metabolism","1.2.1.11"]
["R226","ATP:L-aspartate 4-phosphotransferase","L_ASP[c] + ATP[c]  <=> ADP[c] + 4P_ASP[c] ","TTC0166","ask","Threonine and Lysine Metabolism","2.7.2.4"]
["R227","O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase","OAC_SER[c] + H2S[c]  -> L_CYS[c] + H[c] + AC[c] ","TTC1636","cysM","Cysteine and methionine metabolism","2.5.1.47"]
["R228","O3-acetyl-L-serine:thiosulfate 2-amino-2-carboxyethyltransferase (reducing, L-cysteine-forming)","H[c] + R_TRED[c] + OAC_SER[c] + TSFA[c]  -> L_CYS[c] + AC[c] + O_TRED[c] + SO3[c] ","TTC1636",null,"Cysteine and methionine metabolism","2.5.1.47"]
["R229","L-cysteate:2-oxoglutarate aminotransferase","AKG[c] + L_CYSTA[c]  <=> L_GLU[c] + SULFO_PYR[c] ","TTC1960",null,"Cysteine and methionine metabolism","2.6.1.1"]
["R230","3-sulfino-L-alanine:2-oxoglutarate aminotransferase","AKG[c] + SLF_ALA[c]  <=> L_GLU[c] + SULFI_PYR[c] ","TTC1960",null,"Cysteine and methionine metabolism","2.6.1.1"]
["R231","L-Cysteine hydrogen-sulfide-lyase (deaminating","L_CYS[c] + H2O[c]  -> PYR[c] + NH4[c] + H2S[c] ","TTC1256",null,"Cysteine and methionine metabolism","4.4.1.8"]
["R232","Acetyl-CoA:L-homoserine O-acetyltransferase","ACoA[c] + L_HSER[c]  -> CoA[c] + OAC_HSER[c] ","TTC0407","met2","Cysteine and methionine metabolism","2.3.1.31"]
["R233","O-acetyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase","H2S[c] + OAC_HSER[c]  -> H[c] + AC[c] + L_HCYS[c] ","(TTC0408 or TTC0792)","met17","Cysteine and methionine metabolism","2.5.1.49"]
["R234","L-cystathionine L-homocysteine-lyase (deaminating","H2O[c] + L_CYSTHNN[c]  -> PYR[c] + NH4[c] + L_HCYS[c] ","TTC1256",null,"Cysteine and methionine metabolism","4.4.1.8"]
["R235","5-Methyltetrahydrofolate:L-homocysteine S-methyltransferase","L_HCYS[c] + 5MTHF[c]  -> L_MET[c] + H[c] + THF[c] ","TTC0253","metH","Cysteine and methionine metabolism","2.1.1.13"]
["R236","S-Adenosyl-L-homocysteine homocysteinylribohydrolase","H2O[c] + SAHC[c]  -> ADN[c] + RIBS_HCYS[c] ","TTC1185",null,"Cysteine and methionine metabolism","3.2.2.9"]
["R237","S-(5-deoxy-D-ribos-5-yl)-L-homocysteine homocysteine-lyase [(4S)-4,5-dihydroxypentan-2,3-dione-forming]","RIBS_HCYS[c]  -> L_HCYS[c] + DHY_PENTDON[c] ","TTC1186",null,"Cysteine and methionine metabolism","4.4.1.21"]
["R238","ATP:L-methionine S-adenosyltransferase","L_MET[c] + ATP[c] + H2O[c]  -> Pi[c] + PPi[c] + SAM[c] ","TTC1279",null,"Cysteine and methionine metabolism","2.5.1.6"]
["R239","S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium-forming]","H[c] + SAM[c]  -> CO2[c] + SAMA[c] ","(TTC0473 or TTC1093)",null,"Cysteine and methionine metabolism","4.1.1.50"]
["R240","S-adenosylmethioninamine:putrescine 3-aminopropyltransferase","SAMA[c] + PUT[c]  -> H[c] + MTA[c] + SPRD[c] ","TTC0472",null,"Cysteine and methionine metabolism","2.5.1.16"]
["R241","S-adenosylmethioninamine:spermidine 3-aminopropyltransferase","SAMA[c] + SPRD[c]  <=> H[c] + MTA[c] + SPR[c] ","TTC0472",null,"Cysteine and methionine metabolism","2.5.1.16"]
["R242","Methylthioadenosine methylthioribohydrolase","H2O[c] + MTA[c]  -> ADN[c] + MTH_RIB[c] ","TTC1185",null,"Cysteine and methionine metabolism","3.2.2.9"]
["R243","5-Methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase","MTh_RIB1P[c]  <=> MTh_RIBL1P[c] ","TTC0707",null,"Cysteine and methionine metabolism","5.3.1.23"]
["R244","L-Leucine:2-oxoglutarate aminotransferase","L_GLU[c] + 4M_2OPENTN[c]  <=> L_LEU[c] + AKG[c] ","TTC1870","ilvE","Valine, Leucine, and Isoleucine Metabolism","2.6.1.42"]
["R245","L-Valine:2-oxoglutarate aminotransferase","L_VAL[c] + AKG[c]  <=> L_GLU[c] + 2K3M_BUT[c] ","TTC1870","ilvE","Valine, Leucine, and Isoleucine Metabolism","2.6.1.42"]
["R246","L-Isoleucine:2-oxoglutarate aminotransferase","L_ILE[c] + AKG[c]  <=> L_GLU[c] + 3M_2OPENTN[c] ","TTC1870","ilvE","Valine, Leucine, and Isoleucine Metabolism","2.6.1.42"]
["R247","branched-chain alpha-keto acid dehydrogenase","3M_2OPENTN[c] + TPP[c]  -> CO2[c] + 2MHYBUT_ThPP[c] ","(TTC1756 and TTC1757)","vorA","Valine, Leucine, and Isoleucine Metabolism","1.2.4.4"]
["R248","branched-chain alpha-keto acid dehydrogenase","4M_2OPENTN[c] + TPP[c]  -> CO2[c] + 3MHYBUT_ThPP[c] ","(TTC1756 and TTC1757)","vorA","Valine, Leucine, and Isoleucine Metabolism","1.2.4.4"]
["R249","branched-chain alpha-keto acid dehydrogenase","2K3M_BUT[c] + TPP[c]  -> CO2[c] + 2MHYPROP_ThPP[c] ","(TTC1756 and TTC1757)","vorA","Valine, Leucine, and Isoleucine Metabolism","1.2.4.4"]
["R250","branched-chain alpha-keto acid dehydrogenase","2MHYPROP_ThPP[c] + ENZN6_LPL[c]  -> TPP[c] + DHYLPL_MPROP_MPROP_DHLPL[c] ","(TTC1756 and TTC1757)","vorA","Valine, Leucine, and Isoleucine Metabolism","1.2.4.4"]
["R251","branched-chain alpha-keto acid dehydrogenase","3MHYBUT_ThPP[c] + ENZN6_LPL[c]  -> TPP[c] + DHYLPL_MPROP_3MBUT_DHLPL[c] ","(TTC1756 and TTC1757)","vorA","Valine, Leucine, and Isoleucine Metabolism","1.2.4.4"]
["R252","branched-chain alpha-keto acid dehydrogenase","2MHYBUT_ThPP[c] + ENZN6_LPL[c]  -> TPP[c] + DHYLPL_MPROP_2MBUT_DHLPL[c] ","(TTC1756 and TTC1757)","vorA","Valine, Leucine, and Isoleucine Metabolism","1.2.4.4"]
["R253","(S)-2-methylbutanoyl-CoA:acceptor 2,3-oxidoreductase","FAD[c] + MBUTNCoA[c]  -> FADH2[c] + MBUT_ENCoA[c] ","TTC0238",null,"Valine, Leucine, and Isoleucine Metabolism","1.3.8.1"]
["R254","2-methylpropanoyl-CoA:(acceptor) 2,3-oxidoreductase","FAD[c] + 2M_PROCoA[c]  <=> FADH2[c] + MACRYCoA[c] ","TTC0238",null,"Valine, Leucine, and Isoleucine Metabolism","1.3.8.1"]
["R255","(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA hydro-liase","H2O[c] + MBUT_ENCoA[c]  -> HY_MBUTRCoA[c] ","TTC1768",null,"Valine, Leucine, and Isoleucine Metabolism","4.2.1.17"]
["R256","(S)-3-Hydroxyisobutyryl-CoA hydro-lyase","H2O[c] + MACRYCoA[c]  -> HYIBUTRCoA[c] ","TTC1768",null,"Valine, Leucine, and Isoleucine Metabolism","4.2.1.17"]
["R257","(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming)","HYM_GLUTRCoA[c]  -> ACoA[c] + AAC[c] ","TTC1162",null,"Valine, Leucine, and Isoleucine Metabolism","4.1.3.4"]
["R258","3-Hydroxy-2-methylpropanoate:NAD+ oxidoreductase","NAD[c] + HYIBUTRA[c]  -> H[c] + NADH[c] + MMAL_SA[c] ","(TTC1749 or TTC0534)",null,"Valine, Leucine, and Isoleucine Metabolism","1.1.1.31 or 1.1.1.35"]
["R259","(S)-Methylmalonate semialdehyde:NAD+ oxidoreductase","NAD[c] + H2O[c] + MMAL_SA[c]  -> H[c] + NADH[c] + MMAL[c] ","TTC0513",null,"Valine, Leucine, and Isoleucine Metabolism","1.2.1.3"]
["R260","acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase","CoA[c] + MAACCoA[c]  -> ACoA[c] + PRCoA[c] ","((TTC0535 or TTC0623) or (TTC0191 or TTC0330))",null,"Valine, Leucine, and Isoleucine Metabolism","2.3.1.16 or 2.3.1.9"]
["R261","(R)-Methylmalonyl-CoA CoA-carbonylmutase","R_MMALCoA[c]  <=> SUCCoA[c] ","(TTC0676 and (TTC0677 or TTC0882))",null,"Valine, Leucine, and Isoleucine Metabolism","5.4.99.2"]
["R262","Propanoyl-CoA:carbon-dioxide ligase (ADP-forming)","ATP[c] + HCO3[c] + PRCoA[c]  -> ADP[c] + Pi[c] + H[c] + MMALCoA[c] ","(TTC0783 and TTC1192)",null,"Valine, Leucine, and Isoleucine Metabolism","6.4.1.3"]
["R263","4-hydroxy-tetrahydrodipicolinate synthase","PYR[c] + ASP_4SA[c]  -> 2 H2O[c] + H[c] + DHY_DPICLN[c] ","TTC0591",null,"Threonine and Lysine Metabolism","4.2.1.52"]
["R264","UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate:D-alanyl-D-alanine ligase(ADP-forming)","ATP[c] + UDP_ACMUR_ALA_GLU_DAPIM[c] + D_ALA_D_ALA[c]  -> ADP[c] + Pi[c] + H[c] + UDP_ACMUR_ALA_GLU_DAPIM_ALA_ALA[c] ","TTC0714",null,"Cell Envelope Biosynthesis","6.3.2.10"]
["R265","UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:(L)-meso-2,6-diaminoheptanedioate gamma-ligase (ADP-forming)","ATP[c] + UDP_ACMURM_ALA_GLUT[c] + M26_DAP[c]  -> ADP[c] + Pi[c] + H[c] + UDP_ACMUR_ALA_GLU_DAPIM[c] ","TTC1904",null,"Cell Envelope Biosynthesis","6.3.2.13"]
["R266","acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)","H2O[c] + ACoA[c] + AKG[c]  -> CoA[c] + HCIT[c] ","TTC1550","lysS","Threonine and Lysine Metabolism","2.3.3.14"]
["R267","(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating)","OXLGLUTR[c]  <=> CO2[c] + 2OADPA[c] ","TTC1012","lysN","Threonine and Lysine Metabolism","1.1.1.87"]
["R268","(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating)","NAD[c] + HICTR[c]  <=> H[c] + NADH[c] + OXLGLUTR[c] ","TTC1012","hicdh","Threonine and Lysine Metabolism","1.1.1.87"]
["R269","L-2-aminoadipate:2-oxoglutarate aminotransferase","AKG[c] + AADP[c]  <=> L_GLU[c] + 2OADPA[c] ","TTC0043","lysN","Threonine and Lysine Metabolism","2.6.1.39"]
["R270","N-acetylaminoadipate kinase","ATP[c] + AC_AADP[c]  -> ADP[c] + AC_AADP_DELPi[c] ","(TTC1541 or TTC1586)","lysZ","Threonine and Lysine Metabolism","2.7.2.- "]
["R271","N-acetyl-alpha-aminoadipate-phosphate reductase","H[c] + NADPH[c] + AC_AADP_DELPi[c]  -> NADP[c] + Pi[c] + AC_AADP_SA[c] ","(TTC0386 or TTC1542)","lysY","Threonine and Lysine Metabolism","1.2.1.38"]
["R272","N2-acetyl-L-lysine deacetylase","H2O[c] + N2AC_L_LYS[c]  -> L_LYS[c] + AC[c] ","TTC1396","lysK","Threonine and Lysine Metabolism","3.5.1.-"]
["R273","2-Oxoadipate:lipoamde 2-oxidoreductase(decarboxylating and acceptor-succinylating)","ENZN6_LPL[c] + 2OADPA[c]  -> CO2[c] + DHLPL_SUCCT_GLUTRDHLPL[c] ","TTC1698",null,"Threonine and Lysine Metabolism","1.2.4.2"]
["R274","Glutaryl-CoA:dihydrolipoamide S-succinyltransferase","GLUTRCoA[c] + ENZNE_DHYLPL[c]  <=> CoA[c] + DHLPL_SUCCT_GLUTRDHLPL[c] ","TTC1699",null,"Threonine and Lysine Metabolism","2.3.1.61"]
["R275","4-Trimethylammoniobutanal:NAD+ 1-oxidoreductase","NAD[c] + H2O[c] + TM_AMBUTAL[c]  -> H[c] + NADH[c] + TM_AMBUTAT[c] ","TTC0513",null,"Threonine and Lysine Metabolism","1.2.1.3"]
["R276","1-(5-phospho-D-ribosyl)-ATP:diphosphate phospho-alpha-D-ribosyl-transferase","PPi[c] + PRIB_ATP[c]  <=> ATP[c] + PRPP[c] ","TTC1866","hisG","Histidine Metabolism","2.4.2.17"]
["R277","Phosphoribosyl-ATP pyrophosphohydrolase","H2O[c] + PRIB_ATP[c]  -> PPi[c] + H[c] + PRIB_AMP[c] ","TTC1080","hisI","Histidine Metabolism","3.6.1.31"]
["R278","1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase","H2O[c] + PRIB_AMP[c]  -> PRINS_AFORMA_PRIBS_IMDZ_CARBA[c] ","TTC1080","hisI","Histidine Metabolism","3.5.4.19"]
["R279","N-(5'-Phospho-D-ribosylformimino)-5-amino-1- (5''-phospho-D-ribosyl)-4-imidazolecarboxamide ketol-isomerase","PRINS_AFORMA_PRIBS_IMDZ_CARBA[c]  <=> PRINSFORMA_PRIBS_IMDZ_CARBA[c] ","TTC0801","hisA","Histidine Metabolism","5.3.1.16"]
["R280","Imidazole-glycerol-3-phosphate synthase","L_GLN[c] + PRINSFORMA_PRIBS_IMDZ_CARBA[c]  -> L_GLU[c] + H[c] + AICAR[c] + ERY_IMDZ_GLYCP[c] ","(TTC0062 and TTC1079)","hisF, hisH","Histidine Metabolism","2.4.2.- or 4.1.3.-"]
["R281","D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate hydro-lyase","ERY_IMDZ_GLYCP[c]  -> H2O[c] + IMDZ_ACLP[c] ","TTC0061","hisB","Histidine Metabolism","4.2.1.19"]
["R282","5-Amino-2-oxopentanoate:2-oxoglutarate aminotransferase","AKG[c] + HISDPi[c]  <=> L_GLU[c] + IMDZ_ACLP[c] ","(TTC0060 or TT_P0022)","hisC","Histidine Metabolism","2.6.1.9"]
["R283","L-Histidinol-phosphate phosphohydrolase","H2O[c] + HISDPi[c]  -> Pi[c] + L_HISN[c] ","TTC1652","hisB","Histidine Metabolism","3.1.3.15"]
["R284","L-Histidinol:NAD+ oxidoreductase","2 NAD[c] + H2O[c] + L_HISN[c]  -> L_HIS[c] + 3 H[c] + 2 NADH[c] ","TTC0370","hisD","Histidine Metabolism","1.1.1.23"]
["R285","L-histidinal:NAD+ oxidoreductase","NAD[c] + H2O[c] + L_HISDAL[c]  -> L_HIS[c] + H[c] + NADH[c] ","TTC0370","hisD","Histidine Metabolism","1.1.1.23"]
["R286","Imidazole acetaldehyde:NAD+ oxidoreductase","NAD[c] + H2O[c] + IMDZ_AALD[c]  -> H[c] + NADH[c] + IMDZ_AC[c] ","TTC0513",null,"Histidine Metabolism","1.2.1.3"]
["R287","p-hydroxyphenylpyruvate oxidase","HYPh_PYR[c] + O2[c] + 2 H[c]  <=> HY_PhAC[c] + H2O[c] + CO2[c]",null,null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","1.2.3.13"]
["R288","4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating)","H[c] + NADH[c] + O2[c] + HY_PhAC[c]  <=> NAD[c] + H2O[c] + dHY_PhAC[c] ","TTC0594",null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","1.14.14.9"]
["R289","3,4-dihydroxyphenylacetate dioxygenase","dHY_PhAC[c]  + O2[c] -> H[c] + 2HY_5CARBMMUC_SA[c]",null,null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","1.13.11.15"]
["R290","5-carboxymethyl-2-hydroxymuconic-semialdehyde:NAD+ oxidoreductase","NAD[c] + H2O[c] + 2HY_5CARBMMUC_SA[c]  <=> H[c] + NADH[c] + CARBM_HYMUC[c] ","TTC0593",null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","1.2.1.60"]
["R291","5-carboxymethyl-2-hydroxymuconate isomerase","CARBM_HYMUC[c] -> CO2[c] + CRBX_OHEPTEDA[c]",null,null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","5.3.3.10"]
["R292","5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase","CRBX_OHEPTEDA[c]  -> CO2[c] + HYHEPTDENA[c] ","TTC0592",null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","4.1.1.68"]
["R293","2-hydroxyhepta-2,4-dienedioate hydratase","OHEPEDA[c]  <=> HYHEPTDENA[c] + H2O[c]",null,null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","5.3.3.-"]
["R294","4-hydroxy-2-ketopimelate aldolase","OHEPEDA[c] -> SUCC_SA[c] + PYR[c]",null,null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","4.1.2.-"]
["R295","L-tyrosine:2-oxoglutarate aminotransferase","L_TYR[c] + AKG[c]  <=> L_GLU[c] + HYPh_PYR[c] ","TTC1960","aat","Tyrosine, Tryptophan, and Phenylalanine Metabolism","2.6.1.1"]
["R296","Phenylacetate:CoA ligase","ATP[c] + CoA[c] + PhAC[c]  -> PPi[c] + AMP[c] + PhACoA[c] ","TTC0602",null,"Alternate Carbon Metabolism","6.2.1.30"]
["R297","L-Phenylalanine:2-oxoglutarate aminotransferase","L_PHE[c] + AKG[c]  <=> L_GLU[c] + PPYR[c] ","TTC1960","aat","Tyrosine, Tryptophan, and Phenylalanine Metabolism","2.6.1.1"]
["R298","Phenylpyruvate decarboxylase","PPYR[c] + H[c] -> CO2[c] + PhALD[c]",null,null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","4.1.1.43"]
["R299","Phenylacetaldehyde dehydrogease","PhALD[c] + NAD[c] + H2O[c] -> 2 H[c] + NADH[c] + PhAC[c]",null,null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","1.2.1.39"]
["R300","phenylacetate-CoA oxygenase","PhACoA[c] + H[c] + NADPH[c] + O2[c] -> H2O[c] + NADP[c] + dhPhACoA[c]","TTC0608",null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","1.14.13.149"]
["R301","1,2-epoxyphenylacetyl-CoA isomerase","dhPhAC[c] <=> OPACCoA[c]","TTC1697",null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","5.3.3.18"]
["R302","oxepin-CoA hydrolase","OPACCoA[c] + H2O[c] -> ODHSCoASA[c]","TTC0604",null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","3.7.1.16"]
["R303","3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase","ODHSCoASA[c] + H2O[c] + NADP[c] -> 2 H[c] + NADPH[c] + ODHSCoA[c]","TTC0604",null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","1.17.1.17"]
["R304","beta-ketoadipyl CoA thiolase","ODHSCoA[c] + CoA[c] -> ACoA[c] + DHADPCoA[c]","TTC0623",null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","2.3.1.-"]
["R305","enoyl-CoA hydratase ","DHADPCoA[c] -> H2O[c] + HADPCoA[c]","(TTC0604 or TTC1697 or TTC1768)",null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","4.2.1.17"]
["R306","3-hydroxyacyl-CoA dehydrogenase","HADPCoA[c] + NAD[c] -> NADH[c] + H[c] + OADPCoA[c]","(TTC0331 or TTC0534)",null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","1.1.1.35"]
["R307","beta-ketoadipyl CoA thiolase","OADPCoA[c] + CoA[c] -> ACoA[c] + SUCCoA[c]","TTC0623",null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","2.3.1.174"]
["R308","2-oxoadipate dehydrogenase complex","NAD[c] + CoA[c] + 2OADPA[c]  -> H[c] + NADH[c] + CO2[c] + GLUTRCoA[c] ","(TTC1698 or (TTC1700 or TTC1753) or TTC1699)",null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","1.2.4.2 or 1.8.1.4 or 2.3.1.61"]
["R309","L-aspartate 1-carboxy-lyase (beta-alanine-forming)","L_ASP[c] + H[c]  -> CO2[c] + B_ALA[c] ","TTC0241",null,"Cofactor and Prosthetic Group Biosynthesis","4.1.1.11"]
["R310","beta-alanine:2-oxoglutarate aminotransferase","AKG[c] + B_ALA[c]  <=> L_GLU[c] + MAL_SA[c] ","TTC0510",null,"Beta-Alanine metabolism ","2.6.1.19"]
["R311","malonate-semialdehyde dehydrogenase","MAL_SA[c] + CoA[c] + NAD[c] -> ACoA[c] + CO2[c] + NADH[c]",null,null,"Beta-Alanine metabolism ","1.2.1.-"]
["R312","(R)-Pantoate:beta-alanine ligase (AMP-forming)","ATP[c] + B_ALA[c] + PANTA[c]  -> PPi[c] + H[c] + AMP[c] + PANTO[c] ","TTC1416",null,"Cofactor and Prosthetic Group Biosynthesis","6.3.2.1"]
["R313","UDP-N-acetylmuramate:L-alanine ligase (ADP-forming)","L_ALA[c] + ATP[c] + UDP_ACMURM[c]  -> ADP[c] + Pi[c] + H[c] + UDP_ACMURM_ALA[c] ","TTC0720",null,"Cell Envelope Biosynthesis","6.3.2.8"]
["R314","UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase(ADP-forming)","ATP[c] + D_GLU[c] + UDP_ACMURM_ALA[c]  -> ADP[c] + Pi[c] + H[c] + UDP_ACMURM_ALA_GLUT[c] ","TTC0717",null,"Cell Envelope Biosynthesis","6.3.2.9"]
["R315","glutamate racemase","L_GLU[c]  <=> D_GLU[c] ","TTC1280",null,"Cell Envelope Biosynthesis","5.1.1.3"]
["R316","alanine racemase","L_ALA[c]  <=> D_ALA[c] ","TTC1944",null,"Alanine and Aspartate Metabolism","5.1.1.1"]
["R317","D-alanine:D-alanine ligase (ADP-forming)","ATP[c] + 2 D_ALA[c]  <=> ADP[c] + Pi[c] + H[c] + D_ALA_D_ALA[c] ","TTC1223",null,"Cell Envelope Biosynthesis","6.3.2.4"]
["R318","(2R,3S)-3-methylmalate:NAD+ oxidoreductase","NAD[c] + IPROP_MAL[c]  -> H[c] + NADH[c] + CO2[c] + AKB[c] ","TTC0867",null,"Valine, Leucine, and Isoleucine Metabolism","1.1.1.85"]
["R319","(R)-2,3-Dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)","NADP[c] + RDHY_MBUTNA[c]  <=> H[c] + NADPH[c] + 3HY_2M_2OBUTNA[c] ","TTC0850",null,"Valine, Leucine, and Isoleucine Metabolism","1.1.1.86"]
["R320","(R)-2,3-Dihydroxy-3-methylpentanoate:NADP+ oxidoreductase (isomerizing)","NADP[c] + DHY_MPENTA[c]  <=> H[c] + NADPH[c] + AC_HYBUTNA[c]","TTC0850",null,"Valine, Leucine, and Isoleucine Metabolism","1.1.1.86"]
["R321","(S)-2-Acetolactate methylmutase","S_ACLAC[c]  <=> 3HY_2M_2OBUTNA[c] ","TTC0850",null,"Valine, Leucine, and Isoleucine Metabolism","1.1.1.86"]
["R322","(R)-2,3-Dihydroxy-3-methylpentanoate hydro-lyase","DHY_MPENTA[c]  -> H2O[c] + 3M_2OPENTN[c] ","TTC0871","ilvD","Valine, Leucine, and Isoleucine Metabolism","4.2.1.9"]
["R323","(R)-2,3-Dihydroxy-3-methylbutanoate hydro-lyase","RDHY_MBUTNA[c]  -> H2O[c] + 2K3M_BUT[c] ","TTC0871","ilvD","Valine, Leucine, and Isoleucine Metabolism","4.2.1.9"]
["R324","acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)","H2O[c] + ACoA[c] + 2K3M_BUT[c]  -> CoA[c] + H[c] + IPRO_MAL[c] ","(TTC0847 or TTC0849)","leuA","Valine, Leucine, and Isoleucine Metabolism","2.3.3.13"]
["R325","2-Isopropylmalate hydro-lyase","IPRO_MAL[c]  <=> H2O[c] + IPRO_MALE[c] ","((TTC0865 and TTC0866) or (TTC1546 and TTC1547))","leuCD","Valine, Leucine, and Isoleucine Metabolism","4.2.1.33"]
["R326","3-Isopropylmalate hydro-lyase","IPROP_MAL[c]  <=> H2O[c] + IPRO_MALE[c] ","((TTC0865 and TTC0866) or (TTC1546 and TTC1547))","leuCD","Valine, Leucine, and Isoleucine Metabolism","4.2.1.33"]
["R327","(2R,3S)-3-isopropylmalate:NAD+ oxidoreductase","NAD[c] + IPROP_MAL[c]  <=> H[c] + NADH[c] + IPROP_OSUCC[c] ","TTC0867","leuB","Valine, Leucine, and Isoleucine Metabolism","1.1.1.85"]
["R328","acetyl-CoA:L-glutamate N-acetyltransferase","L_GLU[c] + ACoA[c]  -> CoA[c] + H[c] + AC_GLUT[c] ","(TTC0835 or TTC1703)","argA","Arginine and Proline Metabolism","2.3.1.1"]
["R329","ATP:N-acetyl-L-glutamate 5-phosphotransferase","ATP[c] + AC_GLUT[c]  <=> ADP[c] + AC_GLUTPi[c] ","(TTC1541 or TTC1586)","argB","Arginine and Proline Metabolism","2.7.2.8"]
["R330","N-acetyl-L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphrylating)","H[c] + NADPH[c] + AC_GLUTPi[c]  <=> NADP[c] + Pi[c] + AC_GLUT_SA[c] ","(TTC0836 or TTC1542)","argC","Arginine and Proline Metabolism","1.2.1.38"]
["R331","N2-Acetyl-L-ornithine:2-oxoglutarate aminotransferase","AKG[c] + AORT[c]  <=> L_GLU[c] + AC_GLUT_SA[c] ","TTC1393","argD","Arginine and Proline Metabolism","2.6.1.11"]
["R332","L-Glutamate 5-semialdehyde:NAD+ oxidoreductase","L_GLU[c] + H[c] + NADH[c]  -> NAD[c] + H2O[c] + GLUT_SA[c] ","TTC1213","proA","Arginine and Proline Metabolism","1.5.1.12"]
["R333","L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)","H[c] + NADPH[c] + L_GLUT5P[c]  -> NADP[c] + Pi[c] + GLUT_SA[c] ","TTC1564",null,"Arginine and Proline Metabolism","1.2.1.41"]
["R334","ATP:L-glutamate 5-phosphotransferase","L_GLU[c] + ATP[c]  -> ADP[c] + L_GLUT5P[c] ","TTC1563",null,"Arginine and Proline Metabolism","2.7.2.11"]
["R335","N2-Acetyl-L-ornithine:L-glutamate N-acetyltransferase","L_GLU[c] + AORT[c]  <=> ORT[c] + AC_GLUT[c] ","TTC0835",null,"Arginine and Proline Metabolism","2.3.1.35"]
["R336","N2-Acetyl-L-ornithine amidohydrolase","H2O[c] + AORT[c]  -> ORT[c] + AC[c] ","(TTC0133 or TTC1460)","argE","Arginine and Proline Metabolism","3.5.1.14"]
["R337","Carbamoyl-phosphate:L-ornithine carbamoyltransferase","ORT[c] + CARB_Pi[c]  <=> Pi[c] + H[c] + CTRLN[c] ","TTC0838","argF","Arginine and Proline Metabolism","2.1.3.3"]
["R338","L-Arginine amidinohydrolase","L_ARG[c] + H2O[c]  <=> ORT[c] + UREA[c] ","TTC1132",null,"Arginine and Proline Metabolism","3.5.3.1"]
["R339","urea-1-carboxylate amidohydrolase","H2O[c] + H[c] + UREA_CARB[c]  -> 2 CO2[c] + 2 NH4[c] ","TTC0624",null,"Arginine and Proline Metabolism","3.5.1.54"]
["R340","L-Proline:NAD+ 5-oxidoreductase","L_PRO[c] + NAD[c]  <=> 2 H[c] + NADH[c] + PYRR5CARB[c] ","TTC0500","ProC","Arginine and Proline Metabolism","1.5.1.2"]
["R341","L-Proline:NADP+ 5-oxidoreductase","L_PRO[c] + NADP[c]  <=> 2 H[c] + NADPH[c] + PYRR5CARB[c] ","TTC0500","ProC","Arginine and Proline Metabolism","1.5.1.2"]
["R342","4-hydroxyproline degradation I ","PYRR_3HY_5CARB[c] <=> 2 H[c] + 2 H2O[c] + HYGLU_SA[c]",null,null,"Arginine and Proline Metabolism","spontaneous"]
["R343","L-erythro-4-Hydroxyglutamate:NAD+ oxidoreductase","NAD[c] + H2O[c] + HYGLU_SA[c]  -> H[c] + NADH[c] + ERY_HYGLU[c] ","(TTC1213 or TTC1214)",null,"Arginine and Proline Metabolism","(1.5.1.12 or 1.5.99.8)"]
["R344","L-1-Pyrroline-3-hydroxy-5-carboxylate:NAD+ oxidoreductase","NAD[c] + 2 H2O[c] + PYRR_3HY_5CARB[c]  -> H[c] + NADH[c] + ERY_HYGLU[c] ","TTC1213",null,"Arginine and Proline Metabolism","1.5.1.12"]
["R345","putrescine:2-oxoglutarate aminotransferase","AKG[c] + PUT[c]  -> L_GLU[c] + 4ABUTALD[c] ","TTC0553",null,"Arginine and Proline Metabolism","2.6.1.82"]
["R346","4-aminobutanal:NAD+ 1-oxidoreductase","NAD[c] + H2O[c] + 4ABUTALD[c]  -> 2 H[c] + NADH[c] + 4ABUT[c] ","TTC0513",null,"Arginine and Proline Metabolism","1.2.1.3"]
["R347","trans-4-Hydroxy-L-proline:NAD+ 5-oxidoreductase","H[c] + NADH[c] + PYRR_3HY_5CARB[c]  <=> NAD[c] + tHY_PRO[c] ","TTC0500",null,"Arginine and Proline Metabolism","1.5.1.2"]
["R348","trans-4-Hydroxy-L-proline:NADP+ 5-oxidoreductase","H[c] + NADPH[c] + PYRR_3HY_5CARB[c]  <=> NADP[c] + tHY_PRO[c] ","TTC0500",null,"Arginine and Proline Metabolism","1.5.1.2"]
["R349","proline 4-hydroxylase","L_PRO[c] + AKG[c] + O2[c] <=> tHY_PRO[c] + SUCC[c] + CO2[c]",null,null,"Arginine and Proline Metabolism","1.14.11.-"]
["R350","L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase","AKG[c] + ERY_HYGLU[c]  -> L_GLU[c] + HY_OGLUTR[c] ","TTC1960",null,"Arginine and Proline Metabolism","2.6.1.1"]
["R351","D-4-Hydroxy-2-oxoglutarate glyoxylate-lyase","HY_OGLUTR[c]  -> PYR[c] + GLOXT[c] ","TT_P0030",null,"Arginine and Proline Metabolism"," 4.1.2.14"]
["R352","Agmatine amidinohydrolase","H2O[c] + AGMT[c]  -> PUT[c] + UREA[c] ","TTC0764",null,"Arginine and Proline Metabolism","3.5.3.11"]
["R353","L-arginine carboxy-lyase (agmatine-forming)","L_ARG[c] + H[c]  -> CO2[c] + AGMT[c] ","TTC1277",null,"Arginine and Proline Metabolism","4.1.1.19"]
["R354","2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate phosphate-lyase (cyclyzing)","DHYDO_ARAB_HEPTP[c]  -> Pi[c] + 3DHYQNT[c] ","TTC1020","aroB","Tyrosine, Tryptophan, and Phenylalanine Metabolism","4.2.3.4"]
["R355","3-Dehydroquinate hydro-lyase","3DHYQNT[c]  -> H2O[c] + DHY_SHK[c] ","TTC0989","aroD","Tyrosine, Tryptophan, and Phenylalanine Metabolism","4.2.1.10"]
["R356","ATP:shikimate 3-phosphotransferase","ATP[c] + SHK[c]  -> ADP[c] + H[c] + SHKP[c] ","TTC1019","aroK","Tyrosine, Tryptophan, and Phenylalanine Metabolism","2.7.1.71"]
["R357","Phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase","PEP[c] + SHKP[c]  <=> Pi[c] + CVP_SHK[c] ","TTC0088","aroA","Tyrosine, Tryptophan, and Phenylalanine Metabolism","2.5.1.19"]
["R358","5-O-(1-Carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate-forming)","CVP_SHK[c]  -> Pi[c] + CORM[c] ","(TTC0518 or TTC1018)","aroA","Tyrosine, Tryptophan, and Phenylalanine Metabolism","4.2.3.5"]
["R359","Chorismate pyruvate-lyase (amino-accepting)","L_GLN[c] + CORM[c]  -> L_GLU[c] + H[c] + PYR[c] + ANTHRL[c] ","(TTC1492 and TTC1493)","trpE","Tyrosine, Tryptophan, and Phenylalanine Metabolism","4.1.3.27"]
["R360","L-serine hydro-lyase (adding indole","L_SER[c] + IND[c]  -> L_TRP[c] + H2O[c] ","(TTC0729 and TTC0730)",null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","4.2.1.20"]
["R361","(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase","IND_GLYP[c]  -> GAP[c] + IND[c] ","(TTC0729 and TTC0730)",null,"Tyrosine, Tryptophan, and Phenylalanine Metabolism","4.2.1.20"]
["R362","1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase(cyclizing)","H[c] + CPhA_dRBL5P[c]  -> H2O[c] + CO2[c] + IND_GLYP[c] ","TTC0800","trpC","Tyrosine, Tryptophan, and Phenylalanine Metabolism","4.1.1.48"]
["R363","N-(5-Phospho-beta-D-ribosyl)anthranilate ketol-isomerase","5PRIBS_ANTRL[c]  <=> CPhA_dRBL5P[c] ","TTC1929","trpF","Tyrosine, Tryptophan, and Phenylalanine Metabolism","5.3.1.24"]
["R364","N-(5-Phospho-D-ribosyl)anthranilate:pyrophosphate phosphoribosyl-transferase","PPi[c] + 5PRIBS_ANTRL[c]  <=> PRPP[c] + ANTHRL[c] ","TTC1491","trpD","Tyrosine, Tryptophan, and Phenylalanine Metabolism","2.4.2.18"]
["R365","Chorismate pyruvatemutase","CORM[c]  -> PPHA[c] ","(TTC0020 or TTC0514)","cm","Tyrosine, Tryptophan, and Phenylalanine Metabolism","5.4.99.5"]
["R366","Phosphoenolpyruvate:D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate hydrolysing, 2-carboxy-2-oxoethyl-forming)","H2O[c] + PEP[c] + E4P[c]  -> Pi[c] + DHYDO_ARAB_HEPTP[c] ","(TTC0020 or TTC0448)","aroG","Tyrosine, Tryptophan, and Phenylalanine Metabolism","2.5.1.54"]
["R367","cellobiose glucohydrolase","H2O[c] + CELBS[c]  -> 2 D_GLC[c] ","TT_P0042",null,"Alternate Carbon Metabolism","3.2.1.21"]
["R368","ATP:alpha-D-glucose-1-phosphate adenylyltransferase","ATP[c] + H[c] + G1P[c]  -> PPi[c] + ADP_GLU[c] ","(TTC1976 or TTC1977)",null,"Glycolysis/Gluconeogenesis","2.7.7.27"]
["R369","ADP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase","ADP_GLU[c]  <=> ADP[c] + GLY[c] + H[c]","TTC1980",null,"Alternate Carbon Metabolism","2.4.1.21"]
["R370","1,4-alpha-D-Glucan:orthophosphate alpha-D-glucosyltransferase","Pi[c] + GLY[c]  -> G1P[c]","(TTC0808 and TTC1540 and TTC0897)",null,"Alternate Carbon Metabolism","2.4.1.1"]
["R371","maltose glucohydrolase","H2O[c] + MALT[c]  -> 2 D_GLC[c] ","(TTC0107 or TTC1283 or TT_P0221)",null,"Alternate Carbon Metabolism","3.2.1.20"]
["R372","maltose glucohydrolase","H2O[c] + IMALT[c]  -> 2 D_GLC[c] ","(TTC0107 or TTC1283 or TT_P0221)",null,"Alternate Carbon Metabolism","3.2.1.20"]
["R373","N-Acetyl-D-glucosamine-6-phosphate amidohydrolase","H2O[c] + AC_GLUSAP[c]  -> AC[c] + GLUSAP[c] ","TT_P0025",null,"Alternate Carbon Metabolism","3.5.1.25"]
["R374","UTP:N-acetyl-alpha-D-glucosamine-1-phosphate uridylyltransferase","UTP[c] + H[c] + AC_AGLUCSAPi[c]  -> UDP_AGLUAM[c] + PPi[c] ","TTC0017",null,"Cell Envelope Biosynthesis","2.7.7.23"]
["R375","Acetyl-CoA:D-glucosamine-1-phosphate N-acetyltransferase","ACoA[c] + GLUCSA1P[c]  -> CoA[c] + H[c] + AC_AGLUCSAPi[c] ","TTC0017",null,"Cell Envelope Biosynthesis","2.3.1.157"]
["R376","UDP-N-acetyl-D-glucosamine 2-epimerase","UDP_AGLUAM[c]  -> UDP_AC_MANNA[c] ","TTC0948",null,"Cell Envelope Biosynthesis","5.1.3.14"]
["R377","D-Glucosamine 1-phosphate 1,6-phosphomutase","GLUSAP[c]  <=> GLUCSA1P[c] ","TTC0691",null,"Cell Envelope Biosynthesis","5.4.2.10"]
["R378","UDP-N-acetylmuramate:NADP+ oxidoreductase","H[c] + NADPH[c] + UDP_AC_CARBVIN_GLUCSA[c]  -> UDP_ACMURM[c] + NADP[c] ","TTC0721",null,"Cell Envelope Biosynthesis","1.1.1.158"]
["R379","Phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyl-transferase","UDP_AGLUAM[c] + PEP[c]  -> Pi[c] + UDP_AC_CARBVIN_GLUCSA[c] ","TTC1854",null,"Cell Envelope Biosynthesis","2.5.1.7"]
["R380","1D-myo-Inositol 4-phosphate phosphohydrolase","G6P[c]  -> mINS3P[c]",null,null,"Inositol phosphate metabolism","5.5.1.4"]
["R381","1D-myo-Inositol 3-phosphate phosphohydrolase","H2O[c] + mINS3P[c]  -> Pi[c] + M_INS[c] ","TTC1928",null,"Inositol phosphate metabolism","3.1.3.25"]
["R382","sn-Glycerol-3-phosphate:NAD+ 2-oxidoreductase","H[c] + DHAP[c] + NADH[c]  -> NAD[c] + GLCP[c] ","TTC1378",null,"Alternate Carbon Metabolism","1.1.1.94"]
["R383","sn-Glycerol-3-phosphate:NADP+ 2-oxidoreductase","H[c] + DHAP[c] + NADPH[c]  -> NADP[c] + GLCP[c] ","TTC1378",null,"Alternate Carbon Metabolism","1.1.1.94"]
["R384","acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase","0.334 I150CoA[c] + 0.069 AI150CoA[c] + 0.047 I160CoA[c] + 0.014 C160CoA[c] + 0.0015 C161CoA[c] + 0.45 I170CoA[c] + 0.075 AI171CoA[c] + GLCP[c]  -> CoA[c] + GLY3P[c] ","(TTC0841 or TTC1384)",null,"Glycerolipid metabolism","2.3.1.15"]
["R385","acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase","0.334 I150CoA[c] + 0.069 AI150CoA[c] + 0.047 I160CoA[c] + 0.014 C160CoA[c] + 0.0015 C161CoA[c] + 0.45 I170CoA[c] + 0.075 AI171CoA[c] + GLY3P[c]  -> CoA[c] + PPTD[c] ","TTC0983",null,"Glycerolipid metabolism","2.3.1.51"]
["R386","S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase","SAM[c] + PETHA[c]  -> SAHC[c] + PMETHA[c] ","TTC1366",null,"Glycerophospholipid metabolism","2.1.1.17"]
["R387","phosphatidyl-N-methylethanolamine N-methyltransferase","SAM[c] + PMETHA[c]  -> SAHC[c] + PDMETHA[c] ",null,null,"Glycerophospholipid metabolism","2.1.1.71"]
["R388","phosphatidyl-N-dimethylethanolamine N-methyltransferase","SAM[c] + PDMETHA[c]  -> SAHC[c] + PCHOL[c] ",null,null,"Glycerophospholipid metabolism","2.1.1.71"]
["R389","Transacylase","PCHOL[c] + PETHA[c] -> PX[c] + LYPCHOL[c]",null,null,"Glycerophospholipid metabolism"]
["R390","acyltransferase","LYPCHOL[c] + 0.334 I150CoA[c] + 0.069 AI150CoA[c] + 0.047 I160CoA[c] + 0.014 C160CoA[c] + 0.0015 C161CoA[c] + 0.45 I170CoA[c] + 0.075 AI171CoA[c] -> CoA[c] + PCHOL[c]",null,null,"Glycerophospholipid metabolism"]
["R391","phosphatidic acid phosphatase","PPTD[c] + H2O[c] -> DAG[c] + Pi[c]",null,null,"Glycerophospholipid metabolism"]
["R392","ATP:1,2-diacylglycerol 3-phosphotransferase","ATP[c] + DAG[c]  -> ADP[c] + PPTD[c] ","TTC0682",null,"Glycerolipid metabolism","2.7.1.107"]
["R393","UDP-glucosyltransferase (diglucosyl)","DAG[c] + UDP_GLU[c] -> H[c] + MGDG[c] + UDP[c]",null,null,"Glycerolipid metabolism"]
["R394","UDP-glucosyltransferase (monoglucosyl)","MGDG[c] + UDP_GLU[c] -> H[c] + DGDG[c] + UDP[c]",null,null,"Glycerolipid metabolism"]
["R395","Phsophatidyl-L-serine carboxy-lyase","PPTD_SER[c]  -> CO2[c] + PETHA[c] ","TTC0815",null,"Glycerophospholipid metabolism","4.1.1.65"]
["R396","CTP:phosphatidate cytidyltransferase","CTP[c] + PPTD[c]  -> PPi[c] + CDP_DAG[c] ","TTC0505",null,"Glycerophospholipid metabolism","2.7.7.41"]
["R397","CDPdiacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase","CDP_DAG[c] + GLCP[c] -> CMP[c] + H[c] + PGLYP[c]",null,null,"Glycerophospholipid metabolism"]
["R398","Phosphatidylglycerophosphate phosphohydrolase","PGLYP[c] + H2O[c] -> PGLY[c] + Pi[c]",null,null,"Glycerophospholipid metabolism","3.1.3.27"]
["R399","phosphatidylinositol phosphate synthase","CDP_DAG[c] + mINS3P[c] -> CMP[c] + H[c] + PMINS3P[c]",null,null,"Glycerophospholipid metabolism"]
["R400","1-phosphatidyl-1D-myo-inositol 3-phosphatase","PMINS3P[c] + H2O[c] -> PINS[c] + Pi[c]",null,null,"Glycerophospholipid metabolism","3.1.3.64"]
["R401","cardiolipin synthase","2 PGLY[c] -> CDLPN[c] + GLYCRL[c]",null,null,"Glycerophospholipid metabolism"]
["R402","Digalactosylceramide galactohydrolase","H2O[c] + DGALSCRAMD[c]  -> D_GAL[c] + GALS_CA[c] ","TT_P0072",null,"Sphingolipid metabolism","3.2.1.22"]
["R403","UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:alanyl-D-alanine ligase (ADP-forming)","ATP[c] + D_ALA_D_ALA[c] + UDP_ACMUR_ALA_GLU_LYS[c]  -> ADP[c] + Pi[c] + UDP_MURAC_ALA_GLU_LYS_ALA_ALA[c] ","TTC0714",null,"Cell Envelope Biosynthesis","6.3.2.10"]
["R404","UDPMurAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala):undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide-transferase","UDP_MURAC_ALA_GLU_LYS_ALA_ALA[c] + dt_pc_UNDECP[c]  -> UMP[c] + MURAC_ALA_GLU_LYS_ALA_ALA_DP_UNDECP[c] ","TTC0716",null,"Cell Envelope Biosynthesis","2.7.8.13"]
["R405","UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine:undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide-transferase","UDP_ACMUR_ALA_GLU_DAPIM_ALA_ALA[c] + dt_pc_UNDECP[c]  -> UMP[c] + Undp_ACMUR_ALA_GLU_DAPIM_AALA[c] ","TTC0716",null,"Cell Envelope Biosynthesis","2.7.8.13"]
["R406","UDP-N-acetyl-D-glucosamine:N-acetyl-alpha-D-muramyl(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase","UDP_AGLUAM[c] + MURAC_ALA_GLU_LYS_ALA_ALA_DP_UNDECP[c]  -> UDP[c] + Undp_ACMUR_ACGLSA_ALA_GLU_LYS_AALA[c] ","TTC0719",null,"Cell Envelope Biosynthesis","2.4.1.227"]
["R407","UDP-N-acetyl-D-glucosamine:undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine 4-beta-N-acetylglucosaminlytransferase","UDP_AGLUAM[c] + Undp_ACMUR_ALA_GLU_DAPIM_AALA[c]  -> H[c] + UDP[c] + Undp_ACMUR_ACGLSA_ALA_GLU_DAPIM_AALA[c] ","TTC0719",null,"Cell Envelope Biosynthesis","2.4.1.227"]
["R408","undecaprenyl-diphosphate phosphohydrolase","H2O[c] + dt_pc_UNDECPPi[c]  -> Pi[c] + H[c] + dt_pc_UNDECP[c] ","TTC1814",null,"Cell Envelope Biosynthesis","3.6.1.27"]
["R409","Lactoylglutathione lyase","MGLX[c] + GLUTAT[c] -> LACGLUT[c]","TTC0449",null,"Methylglyoxal Metabolism","4.4.1.5"]
["R410","hydroxyacylglutathione hydrolase","LACGLUT[c] + H2O[c] -> GLUTAT[c] + H[c] + LAC[c]","TTC0485",null,"Methylglyoxal Metabolism","3.1.2.6"]
["R411","glycerone-phosphate phosphate-lyase (methylglyoxal-forming)","DHAP[c]  -> Pi[c] + MGLX[c] ","TTC1443",null,"Methylglyoxal Metabolism","4.2.3.3"]
["R412","ATP:pyruvate,phosphate phosphotransferase","ATP[c] + Pi[c] + PYR[c]  <=> PPi[c] + H[c] + PEP[c] + AMP[c] ","TTC0304",null,"Pyruvate metabolism","2.7.9.1"]
["R413","ATP:pyruvate,water phosphotransferase","ATP[c] + H2O[c] + PYR[c]  -> Pi[c] + 2 H[c] + PEP[c] + AMP[c] ","TTC1136",null,"Glycolysis/Gluconeogenesis","2.7.9.2"]
["R414","(S)-lactate:oxygen 2-oxidoreductase (decarboxylating)","LAC[c] + O2[c]  <=> H2O[c] + CO2[c] + AC[c] ","TTC1744",null,"Pyruvate metabolism","1.13.12.4"]
["R415","Acetyl phosphate phosphohydrolase","H2O[c] + ACPi[c]  -> Pi[c] + H[c] + AC[c] ","TTC0199",null,"Pyruvate metabolism","3.6.1.7"]
["R416","acetyl adenylate:CoA acetyltransferase","CoA[c] + ACADNA[c]  <=> AMP[c] + ACoA[c] ","(TTC0884 or TTC0885 or TTC0886 or TTC0919)",null,"Pyruvate metabolism","6.2.1.1"]
["R417","ATP:acetate adenylyltransferase","ATP[c] + AC[c]  <=> PPi[c] + ACADNA[c] ","(TTC0884 or TTC0885 or TTC0886 or TTC0919)",null,"Pyruvate metabolism","6.2.1.1"]
["R418","(S)-malate:NAD+ oxidoreductase (decarboxylating)","NAD[c] + MAL[c]  -> NADH[c] + PYR[c] + CO2[c] ","TTC0144",null,"Pyruvate metabolism","1.1.1.38"]
["R419","Glycolate oxidase","HY_AC[c] + NAD[c] -> GLOXT[c] + NADH[c] + H[c]","TTC1940",null,"Pyruvate metabolism","1.1.19.14"]
["R420","acetyl-CoA:glyoxylate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)","H2O[c] + ACoA[c] + GLOXT[c]  -> CoA[c] + H[c] + MAL[c] ","TTC0130","aceB","Pyruvate metabolism","2.3.3.9"]
["R421","Formate:tetrahydrofolate ligase (ADP-forming)","ATP[c] + THF[c] + FOR[c]  <=> ADP[c] + Pi[c] + 10F_THF[c] ","TTC1707",null,"Folate Metabolism","6.3.4.3"]
["R422","10-Formyltetrahydrofolate amidohydrolase","H2O[c] + 10F_THF[c]  -> H[c] + THF[c] + FOR[c] ","TTC0957",null,"Folate Metabolism","3.5.1.10"]
["R423","5,10-Methenyltetrahydrofolate 5-hydrolase (decyclizing)","H[c] + 10F_THF[c]  <=> H2O[c] + METHF[c] ","TTC0755",null,"Folate Metabolism","3.5.4.9"]
["R424","5,10-methylenetetrahydrofolate:NADP+ oxidoreductase","NADH[c] + METHF[c]  <=> NAD[c] + 5_10_MNTHF[c] ","TTC0755",null,"Folate Metabolism","1.5.1.5"]
["R425","isocitrate glyoxylate-lyase (succinate-forming)","ICIT[c]  -> SUCC[c] + GLOXT[c] ","TTC1485","aceA","Glyoxylate and dicarboxylate metabolism","4.1.3.1"]
["R426","4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)","4HY_2OGLUTR[c]  <=> PYR[c] + GLOXT[c] ","TT_P0030",null,"Glyoxylate and dicarboxylate metabolism","4.1.3.16"]
["R427","Glycolate:oxygen 2-oxidoreductase","O2[c] + HY_AC[c]  -> GLOXT[c] + H2O2[c] ","(TTC0129 or TTC0443)",null,"Glyoxylate and dicarboxylate metabolism","1.1.3.15"]
["R428","Glycolate:NAD+ oxidoreductase","H[c] + NADH[c] + GLOXT[c]  -> NAD[c] + HY_AC[c] ","TTC0431",null,"Glyoxylate and dicarboxylate metabolism","1.1.1.26"]
["R429","2-Phosphoglycolate phosphohydrolase","H2O[c] + 2P_GLYCA[c]  -> Pi[c] + HY_AC[c] ","TTC1471",null,"Glyoxylate and dicarboxylate metabolism","3.1.3.18"]
["R430","2-Hydroxybutyrate:NAD+ oxidoreductase","NAD[c] + 2HYBUTNA[c]  -> H[c] + NADH[c] + AKB[c] ","TTC0748",null,"Propanoate metabolism","1.1.1.27"]
["R431","Propionyladenylate:CoA propionyltransferase","CoA[c] + PROP_ADNSPi[c]  <=> AMP[c] + PRCoA[c] ","(TTC0884 or TTC0885 or TTC0886 or TTC0919)",null,"Propanoate metabolism","6.2.1.1"]
["R432","ATP:propanoate adenylyltransferase","ATP[c] + PROP[c]  <=> PPi[c] + PROP_ADNSPi[c] ","(TTC0884 or TTC0885 or TTC0886 or TTC0919)",null,"Propanoate metabolism","6.2.1.1"]
["R433","pyruvate:pyruvate acetaldehydetransferase (decarboxylating)","H[c] + 2 PYR[c]  -> CO2[c] + S_ACLAC[c] ","(TTC0851 and TTC0852)","ilvH","Valine, Leucine, and Isoleucine Metabolism","2.2.1.6"]
["R434","glycine synthase","L_GLY[c] + NAD[c] + THF[c]  -> H[c] + NADH[c] + CO2[c] + NH4[c] + 5_10_MNTHF[c] ","(TTC0150 and TTC0151)",null,"Folate Metabolism","1.4.4.2"]
["R435","adenosine nucleotides de novo biosynthesis ","ATP[c] + FMN[c]  -> dATP[c] + H2O[c] + FMNH2[c] ",null,null,"Folate Metabolism"]
["R436","5-Formyltetrahydrofolate cyclo-ligase (ADP-forming)","ATP[c] + FOLNA[c]  <=> ADP[c] + Pi[c] + METHF[c] ","(TTC1247 or TTC1803)",null,"Folate Metabolism","6.3.3.2"]
["R437","5-methyltetrahydrofolate:NADP+ oxidoreductase","2 H[c] + NADPH[c] + 5_10_MNTHF[c]  -> NADP[c] + 5MTHF[c] ","TTC1656",null,"Folate Metabolism","1.5.1.20"]
["R438","5-methyltetrahydrofolate:NAD+ oxidoreductase","2 H[c] + NADH[c] + 5_10_MNTHF[c]  -> NAD[c] + 5MTHF[c] ","TTC1656",null,"Folate Metabolism","1.5.1.20"]
["R439","L-cysteine:[ThiI] sulfurtransferase","L_CYS[c] + ENZ_CYS[c]  -> L_ALA[c] + ENZ_SLUFA_CYS[c] ","(TTC0087 or TTC1373)",null,"Cofactor and Prosthetic Group Biosynthesis","2.8.1.7"]
["R440","ATP:4-amino-2-methyl-5-phosphomethylpyrimidine phosphotransferase","ATP[c] + 4A_M5PM_PYRM[c]  -> ADP[c] + 2M4A_HYMPYRMPPi[c] ","TTC0321",null,"Cofactor and Prosthetic Group Biosynthesis","2.7.4.7"]
["R441","ATP:4-amino-5-hydroxymethyl-2-methylpyrimidine 5-phosphotransferase","ATP[c] + TOPYRM[c]  -> ADP[c] + H[c] + 4A_M5PM_PYRM[c] ","TTC0321",null,"Cofactor and Prosthetic Group Biosynthesis","2.7.1.49"]
["R442","2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:4-methyl-5-(2-phosphoethyl)-thiazole 2-methyl-4-aminopyridine-5-methenyltransferase","H[c] + 2M4A_HYMPYRMPPi[c] + 4M_PE_THZ[c]  -> PPi[c] + TMP[c] ","TTC0315",null,"Cofactor and Prosthetic Group Biosynthesis","2.5.1.3"]
["R443","ATP:thiamin-phosphate phosphotransferase","ATP[c] + TMP[c]  -> ADP[c] + TPP[c] ","TTC0056",null,"Cofactor and Prosthetic Group Biosynthesis","2.7.4.16"]
["R444","Thiamin diphosphate phosphohydrolase","H2O[c] + TPP[c]  -> Pi[c] + H[c] + TMP[c] ",null,null,"Cofactor and Prosthetic Group Biosynthesis","3.6.1.6"]
["R445","Glycine oxidase","L_GLY[c] + O2[c] -> H2O2[c] + H[c] + IMAC[c]","TTC0318",null,"Cofactor and Prosthetic Group Biosynthesis"]
["R446","Thiazole synthase","IMAC[c] + L_CYS[c] + dXYLL5P[c] + ATP[c] -> THZ[c] + 2 H2O[c] + AMP[c] + L_ALA[c] + PPi[c]","TTC0317",null,"Cofactor and Prosthetic Group Biosynthesis","2.8.1.10"]
["R447","Thiazole isomerase","THZ[c] <=> 4M_PE_THZ[c]",null,null,"Cofactor and Prosthetic Group Biosynthesis","5.3.99.10"]
["R448","D-ribulose 5-phosphate formate-lyase (L-3,4-dihydroxybutan-2-one 4-phosphate-forming)","RBL5P[c]  -> H[c] + FOR[c] + DHY_BUTNPi[c] ","TTC0697",null,"Cofactor and Prosthetic Group Biosynthesis","4.1.99.12"]
["R449","GTP 7,8-8,9-dihydrolase (diphosphate-forming)","GTP[c] + 3 H2O[c]  -> PPi[c] + 2 H[c] + FOR[c] + DA_PRIBSA_PYMDN[c] ","TTC0697",null,"Cofactor and Prosthetic Group Biosynthesis","3.5.4.25"]
["R450","5-amino-6-(5-phosphoribitylamino)uracil:NADP+ 1'-oxidoreductase","H[c] + NADPH[c] + AP_RIB_URA[c]  -> NADP[c] + APRIBTA_URA[c] ","TTC0699",null,"Cofactor and Prosthetic Group Biosynthesis","1.1.1.193"]
["R451","ATP:riboflavin 5'-phosphotransferase","ATP[c] + RBFLV[c]  -> ADP[c] + H[c] + FMN[c] ","TTC0159",null,"Cofactor and Prosthetic Group Biosynthesis","2.7.1.26"]
["R452","ATP:FMN adenylyltransferase","ATP[c] + H[c] + FMN[c]  -> PPi[c] + FAD[c] ","TTC0159",null,"Cofactor and Prosthetic Group Biosynthesis","2.7.7.2"]
["R453","riboflavin-5-phosphate phosphohydrolase (acid optimum)","H2O[c] + FMN[c]  -> RBFLV[c] + Pi[c] ","TTC1252",null,"Cofactor and Prosthetic Group Biosynthesis","3.1.3.2"]
["R454","Nicotinate-nucleotide:dimethylbenzimidazole phospho-D-ribosyltransferase","NC_D_RNUC[c] + CBMCo[c]  -> H[c] + NIA[c] + PRIBS_DMBENZ_IMDZ[c] ","TT_P0005",null,"Cofactor and Prosthetic Group Biosynthesis","2.4.2.21"]
["R455","2,5-Diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine 2-aminohydrolase","H2O[c] + H[c] + DA_PRIBSA_PYMDN[c]  -> NH4[c] + AP_RIB_URA[c] ","TTC0699",null,"Cofactor and Prosthetic Group Biosynthesis","3.5.4.26"]
["R456","5-amino-6-(D-ribitylamino)uracil butanedionetransferase","DHY_BUTNPi[c] + 5AM_RIBAM_URA[c]  -> Pi[c] + 2 H2O[c] + DM_DR_LUM[c] ","TTC1647",null,"Cofactor and Prosthetic Group Biosynthesis","2.5.1.78"]
["R457","O-Phospho-4-hydroxy-L-threonine phospho-lyase (adding water)","H2O[c] + OPHY_THR[c]  -> Pi[c] + HY_THR[c] ","TTC0117",null,"Cofactor and Prosthetic Group Biosynthesis","4.2.3.1"]
["R458","Nicotinate D-ribonucleotide:diphosphate phosphoribosyltransferase","H[c] + PRPP[c] + NIA[c]  -> PPi[c] + NC_D_RNUC[c] ","TTC0252",null,"Cofactor and Prosthetic Group Biosynthesis","2.4.2.11"]
["R459","N-Ribosylnicotinamide:orthophosphate ribosyltransferase","Pi[c] + RIBS_NCTA[c]  <=> R1P[c] + NAMD[c] ","(TTC0194 or TTC1070)",null,"Cofactor and Prosthetic Group Biosynthesis","2.4.2.1"]
["R460","Nicotinate D-ribonucleoside:orthophosphate ribosyltransferase","Pi[c] + NICRIB[c]  <=> H[c] + R1P[c] + NIA[c] ","(TTC0194 or TTC1070)",null,"Cofactor and Prosthetic Group Biosynthesis","2.4.2.1"]
["R461","Nicotinamide ribonucleotide phosphohydrolase","H2O[c] + NMN[c]  -> Pi[c] + RIBS_NCTA[c] ","(TTC0964 or TTC1625 or TT_P0028)",null,"Cofactor and Prosthetic Group Biosynthesis","3.1.3.5"]
["R462","Nicotinate-nucleotide:pyrophosphate phosphoribosyltransferase (carboxylating)","2 H[c] + PRPP[c] + QA[c]  -> PPi[c] + CO2[c] + NC_D_RNUC[c] ","TTC0621",null,"Cofactor and Prosthetic Group Biosynthesis","2.4.2.19"]
["R463","ATP:nicotinamide-nucleotide adenylyltransferase","ATP[c] + H[c] + NMN[c]  -> NAD[c] + PPi[c] ","TTC1421",null,"Cofactor and Prosthetic Group Biosynthesis","2.7.7.18"]
["R464","deamido-NAD+:ammonia ligase (AMP-forming)","ATP[c] + NH4[c] + DA_NAD[c]  -> NAD[c] + PPi[c] + H[c] + AMP[c] ","TTC1538",null,"Cofactor and Prosthetic Group Biosynthesis","6.3.1.5"]
["R465","NADPH:NAD+ oxidoreductase","NAD[c] + NADPH[c]  -> NADP[c] + NADH[c] ","(TTC1778 and (TTC1779 or TTC1780))",null,"Oxidative Phosphorylation","1.6.1.1 and 1.6.1.2"]
["R466","L-aspartate:oxygen oxidoreductase","L_ASP[c] + O2[c]  -> H[c] + H2O2[c] + IMASP[c] ","TTC0619",null,"Cofactor and Prosthetic Group Biosynthesis","1.4.3.16"]
["R467","glycerone phosphate:iminosuccinate alkyltransferase (cyclizing)","DHAP[c] + IMASP[c]  -> Pi[c] + 2 H2O[c] + QA[c] ","TTC0620",null,"Cofactor and Prosthetic Group Biosynthesis","2.5.1.72"]
["R468","Nicotinate D-ribonucleotide phosphohydrolase","H2O[c] + NC_D_RNUC[c]  -> Pi[c] + NICRIB[c] ","(TTC0964 or TTC1625 or TT_P0028)",null,"Cofactor and Prosthetic Group Biosynthesis","3.1.3.5"]
["R469","ATP:nicotinamide-nucleotide adenylyltransferase","ATP[c] + H[c] + NC_D_RNUC[c]  <=> PPi[c] + DA_NAD[c] ","TTC1421",null,"Cofactor and Prosthetic Group Biosynthesis","2.7.7.18"]
["R470","6-Carboxyhyxanoate:CoA ligase (AMP-forming)","ATP[c] + CoA[c] + PIM[c]  <=> PPi[c] + AMP[c] + PIMCoA[c] ","TTC1711",null,"Cofactor and Prosthetic Group Biosynthesis","6.2.1.14"]
["R471","dethiobiotin:sulfur sulfurtransferase","2 SAM[c] + DTBTN[c] + S[c]  -> 2 L_MET[c] + H[c] + BTN[c] + 2 dADNS[c] ","TTC0242",null,"Cofactor and Prosthetic Group Biosynthesis","2.8.1.6"]
["R472","biotin:CoA ligase (AMP-forming)","ATP[c] + BTN[c]  -> PPi[c] + BTN_AMP[c] ","TTC1761",null,"Cofactor and Prosthetic Group Biosynthesis","6.3.4.15"]
["R473","Biotinyl-5'-AMP:apo-[carboxylase] ligase (AMP-forming)","BTN_AMP[c] + APCARB[c]  -> AMP[c] + HCARB[c] ","TTC1761",null,"Cofactor and Prosthetic Group Biosynthesis","6.3.4.15"]
["R474","octanoyl-[acp]:sulfur sulfurtransferase","2 SAM[c] + OCT_ACP[c] + 2 S[c]  -> 2 L_MET[c] + 2 dADNS[c] + LP_ACP[c] ","TTC1747",null,"Lipoic acid metabolism ","2.8.1.8"]
["R475","protein N6-(octanoyl)lysine:sulfur sulfurtransferase","2 SAM[c] + 2 S[c] + PN6_OCTLYS[c]  -> 2 L_MET[c] + 2 dADNS[c] + PN6_LPLYS[c] ","TTC1747",null,"Lipoic acid metabolism ","2.8.1.8"]
["R476","octanoyl-[acp]:protein N6-octanoyltransferase","OCT_ACP[c] + APPRO[c]  -> ACP[c] + PN6_OCTLYS[c] ","TTC1746",null,"Lipoic acid metabolism ","2.3.1.181"]
["R477","lipoyl-[acp]:protein N6-lipoyltransferase","LP_ACP[c] + APPRO[c]  -> ACP[c] + PN6_LPLYS[c] ","TTC1746",null,"Lipoic acid metabolism ","2.3.1.181"]
["R478","2,3-Dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)","H[c] + NADPH[c] + S_ACLAC[c]  <=> NADP[c] + DHY_MBUTNA[c] ","TTC0850",null,"Cofactor and Prosthetic Group Biosynthesis","1.1.1.86"]
["R479","2,3-Dihydroxy-3-methylbutanoate hydro-lyase","DHY_MBUTNA[c]  -> H2O[c] + 2K3M_BUT[c] ","TTC0871",null,"Cofactor and Prosthetic Group Biosynthesis","4.2.1.9"]
["R480","5,10-Methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase","H2O[c] + 5_10_MNTHF[c] + 2K3M_BUT[c]  -> THF[c] + DHY_PAN[c] ","TTC0039",null,"Cofactor and Prosthetic Group Biosynthesis","2.1.2.11"]
["R481","ATP:pantothenate 4'-phosphotransferase","ATP[c] + PANTO[c]  -> ADP[c] + H[c] + PPANT[c] ","TTC1008",null,"Cofactor and Prosthetic Group Biosynthesis","2.7.1.33"]
["R482","(R)-4'-Phosphopantothenate:L-cysteine ligase","L_CYS[c] + CTP[c] + PPANT[c]  -> PPi[c] + H[c] + CMP[c] + PPANTN_CYS[c] ","TTC1195",null,"Cofactor and Prosthetic Group Biosynthesis","6.3.2.5"]
["R483","N-[(R)-4'-Phosphopantothenoyl]-L-cysteine carboxy-lyase","H[c] + PPANTN_CYS[c]  -> CO2[c] + PANTE4Pi[c] ","TTC1195",null,"Cofactor and Prosthetic Group Biosynthesis","4.1.1.36"]
["R484","ATP:pantetheine-4'-phosphate adenylyltransferase","ATP[c] + H[c] + PANTE4Pi[c]  -> PPi[c] + DPCoA[c] ","TTC0560",null,"Cofactor and Prosthetic Group Biosynthesis","2.7.7.3"]
["R485","ATP:dephospho-CoA 3'-phosphotransferase","ATP[c] + DPCoA[c]  -> CoA[c] + ADP[c] + H[c] ","TTC0557",null,"Cofactor and Prosthetic Group Biosynthesis","2.7.1.24"]
["R486","GTP 8,9-hydrolase","GTP[c] + H2O[c]  -> FAPYRM_NTP[c] ","TTC1517",null,"Cofactor and Prosthetic Group Biosynthesis","3.5.4.16"]
["R487","formamidopyrimidine nucleoside triphosphate amidohydrolase","H2O[c] + FAPYRM_NTP[c]  -> FOR[c] + DAPYRM_NTP[c] ","TTC1517",null,"Cofactor and Prosthetic Group Biosynthesis","3.5.4.16"]
["R488","2,5-Diaminopyrimidine nucleoside triphosphate mutase","DAPYRM_NTP[c]  -> DA_TPiTHY_OPENTAOPYRM[c] ","TTC1517",null,"Cofactor and Prosthetic Group Biosynthesis","3.5.4.16"]
["R489","2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate hydrolase","DA_TPiTHY_OPENTAOPYRM[c]  -> H2O[c] + AHYRY_THYPROP_DHYPTRN_TPi[c] ","TTC1517",null,"Cofactor and Prosthetic Group Biosynthesis","3.5.4.16"]
["R490","2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate phosphohydrolase (alkaline optimum)","3 H2O[c] + AHYRY_THYPROP_DHYPTRN_TPi[c]  -> 3 Pi[c] + 2 H[c] + DHY_NPTRN[c] ","TT_P0024",null,"Cofactor and Prosthetic Group Biosynthesis","3.1.3.1"]
["R491","2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase","DHY_NPTRN[c]  -> H[c] + GLYCALD[c] + AHY_HYM_DHYPTR[c] ","TTC1796",null,"Cofactor and Prosthetic Group Biosynthesis","4.1.2.25"]
["R492","ATP:2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine 6'-pyrophosphotransferase","ATP[c] + AHY_HYM_DHYPTR[c]  -> H[c] + AMP[c] + ADHY_DPOM_PTRDN[c] ","TTC1387",null,"Cofactor and Prosthetic Group Biosynthesis","2.7.6.3"]
["R493","2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase","ADHY_DPOM_PTRDN[c] + ABEE[c]  -> PPi[c] + DHY_PTR[c] ","TTC1795",null,"Cofactor and Prosthetic Group Biosynthesis","2.5.1.15"]
["R494","2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase","AHY_HYM_DHYPTR[c] + ABEE[c]  -> H2O[c] + DHY_PTR[c] ","TTC1795",null,"Cofactor and Prosthetic Group Biosynthesis","2.5.1.15"]
["R495","Tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming)","L_GLU[c] + ATP[c] + THF[c]  <=> ADP[c] + Pi[c] + THF_GLUT[c] ","(TTC0975 or TTC1640)",null,"Cofactor and Prosthetic Group Biosynthesis","6.3.2.17"]
["R496","7,8-dihydropteroate:L-glutamate ligase (ADP-forming)","L_GLU[c] + ATP[c] + DHY_PTR[c]  -> ADP[c] + Pi[c] + H[c] + DHF[c] ","(TTC0975 or TTC1640)",null,"Cofactor and Prosthetic Group Biosynthesis","6.3.2.17"]
["R497","1-Deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating)","H[c] + GAP[c] + PYR[c]  -> CO2[c] + dXYLL5P[c] ","TTC1614","dxs","Cofactor and Prosthetic Group Biosynthesis","2.2.1.7"]
["R498","1-Deoxy-D-xylulose-5-phosphate isomeroreductase","H[c] + NADPH[c] + dXYLL5P[c]  -> NADP[c] + MEROLPi[c] ","TTC0504","dxr","Cofactor and Prosthetic Group Biosynthesis","1.1.1.267"]
["R499","CTP: 2-C-Methyl-D-erythritol 4-phosphate cytidylyltransferase","CTP[c] + H[c] + MEROLPi[c]  -> PPi[c] + CYTPPi_MEROL[c] ","TTC1815","ispD","Cofactor and Prosthetic Group Biosynthesis","2.7.7.60"]
["R500","ATP:4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol 2-phosphotransferase","ATP[c] + CYTPPi_MEROL[c]  -> ADP[c] + H[c] + PCYTPPi_MEROL[c] ","TTC1816","ispE","Cofactor and Prosthetic Group Biosynthesis","2.7.1.148"]
["R501","2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing)","PCYTPPi_MEROL[c]  -> CMP[c] + MEROL_CYCPPi[c] ","TTC1438","ispF","Cofactor and Prosthetic Group Biosynthesis","4.6.1.12"]
["R502","(E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:oxidized ferredoxin oxidoreductase (hydrating)","H[c] + MEROL_CYCPPi[c] + 2 R_FRDX[c]  -> H2O[c] + HY_MBUTEPPi[c] + 2 O_FRDX[c] ","TTC1677","ispG","Cofactor and Prosthetic Group Biosynthesis","1.17.7.1"]
["R503","isopentenyl-diphosphate:NAD(P)+ oxidoreductase","H[c] + NADPH[c] + HY_MBUTEPPi[c]  -> NADP[c] + H2O[c] + IPEN_PPi[c] ","TTC1983","ispH","Cofactor and Prosthetic Group Biosynthesis","1.17.1.2"]
["R504","dimethyallyl diphosphate:NADP+ oxidoreductase","H[c] + NADPH[c] + HY_MBUTEPPi[c]  -> NADP[c] + H2O[c] + DMAPP[c] ","TTC1983","ispH","Cofactor and Prosthetic Group Biosynthesis","1.17.1.2"]
["R505","isopentenyl-diphosphate:NAD+ oxidoreductase","H[c] + NADH[c] + HY_MBUTEPPi[c]  -> NAD[c] + H2O[c] + IPEN_PPi[c] ","TTC1983","ispH","Cofactor and Prosthetic Group Biosynthesis","1.17.1.2"]
["R506","dimethyallyl diphosphate:NAD+ oxidoreductase","H[c] + NADH[c] + HY_MBUTEPPi[c]  -> NAD[c] + H2O[c] + DMAPP[c] ","TTC1983","ispH","Cofactor and Prosthetic Group Biosynthesis","1.17.1.2"]
["R507","Z-farnesyl diphosphate synthase","IPEN_PPi[c] + GRN_PPi[c]  -> PPi[c] + ct_FARPPi[c] ","TTC1551",null,"Cofactor and Prosthetic Group Biosynthesis","2.5.1.68"]
["R508","Dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase","IPEN_PPi[c] + DMAPP[c]  -> PPi[c] + GRN_PPi[c] ","TTC1986","ispA","Cofactor and Prosthetic Group Biosynthesis","2.5.1.1"]
["R509","Isopentenyl-diphosphate delta3-delta2-isomerase","IPEN_PPi[c]  <=> DMAPP[c] ","(TT_P0067 or  TTC0228)",null,"Cofactor and Prosthetic Group Biosynthesis","5.3.3.2"]
["R510","Geranyl-diphosphate:isopentenyl-diphosphate geranyltrans-transferase","IPEN_PPi[c] + GRN_PPi[c]  -> PPi[c] + FAR_PPi[c] ","TTC1986",null,"Cofactor and Prosthetic Group Biosynthesis","2.5.1.10"]
["R511","trans,trans-Farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase","IPEN_PPi[c] + FAR_PPi[c]  -> PPi[c] + GRN_GRNPPi[c] ","TTC1986","ggpps","Cofactor and Prosthetic Group Biosynthesis","2.5.1.29"]
["R512","carvone reductase","H[c] + CRVN[c]  -> IDHY_CRVN[c] ",null,null,"Limonene and pinene degradation","1.3.99.25"]
["R513","geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase","2 GRN_GRNPPi[c]  -> 2 PPi[c] + PHTEN[c] ","TT_P0057","crtB","Carotenoid biosynthesis","2.5.1.32"]
["R514","15-cis-phytoene:plastoquinone oxidoreductase","FAD[c] + PHTEN[c]  -> FADH2[c] + PHFLN[c] ","(TT_P0047 or TT_P0066)","crtI","Carotenoid biosynthesis","1.3.5.5"]
["R515","15-cis-phytoene:acceptor oxidoreductase","FAD[c] + PHFLN[c]  <=> FADH2[c] + zCARO[c] ","TT_P0066","crtI","Carotenoid biosynthesis","1.3.99.28"]
["R516","Neurosporene, hydrogen-donor:oxygen oxidoreductase","FADH2[c] + O2[c] + NRSPENE[c]  -> LCPN[c] + 2 H2O[c] + FAD[c] ","TT_P0066","crtI","Carotenoid biosynthesis","1.3.99.28"]
["R517","zeta-Carotene, hydrogen-donor:oxygen oxidoreductase","FADH2[c] + zCARO[c] + O2[c]  -> 2 H2O[c] + FAD[c] + NRSPENE[c] ","TT_P0066","crtI","Carotenoid biosynthesis","1.3.99.28"]
["R518","ethylnitronate:oxygen 2-oxidoreductase (nitrite-forming)","FMNH2[c] + O2[c] + ENITRN[c]  -> H2O[c] + AALD[c] + FMN[c] + NO2[c] ","TTC1901",null,"Nitrogen metabolism","1.13.12.16"]
["R519","Ammonia:ferredoxin oxidoreductase","7 H[c] + 6 R_FRDX[c] + NO2[c]  <=> 2 H2O[c] + NH4[c] + 6 O_FRDX[c] ","TTC0313",null,"Nitrogen metabolism","1.7.7.1"]
["R520","L-Glutamine amidohydrolase","L_GLN[c] + H2O[c]  -> L_GLU[c] + NH4[c] ","(TTC1104 or TTC0282 or (TTC0247 or TTC1706))",null,"Glutamate Metabolism","1.4.1.13 or 6.3.5.4 or 6.3.5.5"]
["R521","L-aspartate:L-glutamine amido-ligase (AMP-forming)","L_ASP[c] + L_GLN[c] + ATP[c] + H2O[c]  <=> L_GLU[c] + L_ASN[c] + PPi[c] + H[c] + AMP[c] ","TTC0282",null,"Alanine and Aspartate Metabolism","6.3.5.4"]
["R522","Sulfite:ferricytochrome-c oxidoreductase","H2O[c] + 2 CYT_C3[c] + SO3[c]  -> 2 CYT_C2[c] + SO4[c] ","(TTC1046 or TTC1650)",null,"Sulfur metabolism ","1.8.2.1"]
["R523","adenosine 3',5'-bisphosphate,sulfite:oxidized-thioredoxin oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate -forming)","R_TRED[c] + PAPS[c]  -> 2 H[c] + O_TRED[c] + SO3[c] + PAP[c] ","(TTC0310 or TTC0961)",null,"Sulfur metabolism ","1.8.4.8"]
["R524","Cystathionine L-homocysteine-lyase (deaminating)","H2O[c] + CYSTHN[c]  -> PYR[c] + NH4[c] + L_HCYS[c] ","TTC1256",null,"Sulfur metabolism ","4.4.1.8"]
["R525","5,10-methylenetetrahydromethanopterin:glycine hydroxymethyltransferase","L_SER[c] + H4MPT[c]  -> L_GLY[c] + H2O[c] + METHMPTR[c] ","TTC1160",null,"Methane metabolism","2.1.2.1"]
["R526","(R)-2-phospho-3-sulfolactate phosphohydrolase","H2O[c] + PSULFLAC[c]  <=> Pi[c] + SULFLAC[c] ","TTC1073",null,"Methane metabolism","3.1.3.71"]
["R527","Uroporphyrinogen I carboxy-lyase","UPPHYRGN_I[c]  <=> 4 H[c] + 4 CO2[c] + CPPHYRGN_I[c] ","TTC0232",null,"Cofactor and Prosthetic Group Biosynthesis","4.1.1.37"]
["R528","Uroporphyrinogen-III carboxy-lyase","4 H[c] + UPPHYRGN_III[c]  -> 4 CO2[c] + CPPPHYRGN[c] ","TTC0232",null,"Cofactor and Prosthetic Group Biosynthesis","4.1.1.37"]
["R529","5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing","2 ALEVU[c]  -> 2 H2O[c] + H[c] + PPBLGN[c] ","TTC1234",null,"Cofactor and Prosthetic Group Biosynthesis","4.2.1.24"]
["R530","porphobilinogen:(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)","H2O[c] + 4 PPBLGN[c]  -> 4 NH4[c] + HY_MBILN[c] ","TTC1638",null,"Cofactor and Prosthetic Group Biosynthesis","2.5.1.61"]
["R531","Hydroxymethylbilane hydro-lyase(cyclizing)","HY_MBILN[c]  -> H2O[c] + UPPHYRGN_III[c] ","(TTC0312 or TTC1143)",null,"Cofactor and Prosthetic Group Biosynthesis","4.2.1.75"]
["R532","coproporphyrinogen-III:S-adenosyl-L-methionine oxidoreductase(decarboxylating)","2 SAM[c] + CPPPHYRGN[c]  -> 2 L_MET[c] + 2 CO2[c] + 2 dADNS[c] + PPPHYRGN[c] ","TTC0123",null,"Cofactor and Prosthetic Group Biosynthesis","1.3.99.22"]
["R533","protoporphyrinogen-IX:oxygen oxidoreductase","3 O2[c] + PPPHYRGN[c]  -> 3 H2O2[c] + PPPHYR[c] ","TTC0230",null,"Cofactor and Prosthetic Group Biosynthesis","1.3.3.4"]
["R534","protoheme ferro-lyase (protoporphyrin-forming)","PPPHYR[c] + Fe2[c]  -> 2 H[c] + HEME[c] ","TTC0231",null,"Cofactor and Prosthetic Group Biosynthesis","4.99.1.1"]
["R535","(S)-4-Amino-5-oxopentanoate 4,5-aminomutase","GLU_SA[c]  <=> ALEVU[c] ","TTC0564",null,"Cofactor and Prosthetic Group Biosynthesis","5.4.3.8"]
["R536","S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase","2 SAM[c] + UPPHYRGN_III[c]  -> H[c] + 2 SAHC[c] + PRCRN[c] ","(TTC0308 or TT_P0017)",null,"Cofactor and Prosthetic Group Biosynthesis","2.1.1.107"]
["R537","Magnesium-protoporphyrin IX chelatase","ATP[c] + H2O[c] + PPPHYR[c] + Mg[c]  -> ADP[c] + Pi[c] + 3 H[c] + Mg_PPPHYR[c] ","TTC0268",null,"Cofactor and Prosthetic Group Biosynthesis","6.6.1.1"]
["R538","protoheme IX farnesyltransferase","H2O[c] + FAR_PPi[c] + HEME[c]  -> PPi[c] + HEMO[c] ",null,null,"Cofactor and Prosthetic Group Biosynthesis","2.5.1.-"]
["R539","S-Adenosyl-L-methionine:uroporphyrin-III C-methyltransferase","Fe2[c] + SRHYCLR[c]  -> 3 H[c] + SHEME[c] ","TTC0311",null,"Cofactor and Prosthetic Group Biosynthesis","4.99.1.4"]
["R540","S-Adenosyl-L-methionine:uroporphyrin-III C-methyltransferase","NAD[c] + PRCRN[c]  -> H[c] + NADH[c] + SRHYCLR[c] ","TTC0311",null,"Cofactor and Prosthetic Group Biosynthesis","1.3.1.76"]
["R541","S-adenosyl-L-methionine:precorrin-4 C20-methyltransferase","SAM[c] + PRCRN[c]  -> H[c] + SAHC[c] + PRCRN3A[c] ","TT_P0011",null,"Cofactor and Prosthetic Group Biosynthesis","2.1.1.130"]
["R542","S-adenosyl-L-methionine:cobalt-factor-II C20-methyltransferase","SAM[c] + CoSRHYCLR[c]  -> SAHC[c] + CoFIII[c] ","TT_P0011",null,"Cofactor and Prosthetic Group Biosynthesis","2.1.1.151"]
["R543","precorrin-3B C17-methyltransferase","H[c] + SAM[c] + CoPRCRN3[c]  -> SAHC[c] + CoPRCRN4[c] ","TT_P0013",null,"Cofactor and Prosthetic Group Biosynthesis","2.1.1.131"]
["R544","S-adenosyl-L-methionine:precorrin-3B C17-methyltransferase","SAM[c] + PRCRN3B[c]  -> 2 H[c] + SAHC[c] + PRCRN4[c] ","TT_P0013",null,"Cofactor and Prosthetic Group Biosynthesis","2.1.1.131"]
["R545","S-adenosyl-L-methionine:precorrin-4 C11 methyltransferase","SAM[c] + PRCRN4[c]  -> H[c] + SAHC[c] + PRCRN5[c] ","TT_P0012",null,"Cofactor and Prosthetic Group Biosynthesis","2.1.1.133"]
["R546","cobalt-precorrin-4 methyltransferase","SAM[c] + CoPRCRN4[c]  -> SAHC[c] + CoPRCRN5A[c] ","TT_P0012",null,"Cofactor and Prosthetic Group Biosynthesis","2.1.1.133"]
["R547","S-Adenosyl-L-methionine:1-precorrin-6Y C5,15-methyltransferase (C-12-decarboxylating)","2 SAM[c] + PRCRN6B[c]  -> 2 H[c] + CO2[c] + 2 SAHC[c] + PRCRN8X[c] ","TT_P0010",null,"Cofactor and Prosthetic Group Biosynthesis","2.1.1.132"]
["R548","precorrin-8X methylmutase","PRCRN8X[c]  -> HOBYRNA[c] ","TT_P0009",null,"Cofactor and Prosthetic Group Biosynthesis","5.4.1.2"]
["R549","precorrin-8X methylmutase","CoPRCRN8[c]  -> CBRYNA[c] ","TT_P0009",null,"Cofactor and Prosthetic Group Biosynthesis","5.4.1.2"]
["R550","cobyrinic acid A,C-diamide synthase","2 L_GLN[c] + 2 ATP[c] + 2 H2O[c] + HOBYRNA[c]  -> 2 L_GLU[c] + 2 ADP[c] + 2 Pi[c] + 2 H[c] + HOBYRNDA[c] ","TT_P0001",null,"Cofactor and Prosthetic Group Biosynthesis","6.3.5.9"]
["R551","cobyrinate:L-glutamine amido-ligase (ADP-forming)","2 L_GLN[c] + 2 ATP[c] + 2 H2O[c] + CBRYNA[c]  -> 2 L_GLU[c] + 2 ADP[c] + 2 Pi[c] + 3 H[c] + Co2ABYRDA[c] ","TT_P0001",null,"Cofactor and Prosthetic Group Biosynthesis","6.3.5.11"]
["R552","adenosylcobyric acid synthase (glutamine-hydrolysing)","4 L_GLN[c] + 4 ATP[c] + 4 H2O[c] + ADNS_CABYRDA[c]  -> 4 L_GLU[c] + 4 ADP[c] + 4 Pi[c] + 4 H[c] + ADNS_CABYRHA[c] ","TT_P0023",null,"Cofactor and Prosthetic Group Biosynthesis","6.3.5.10"]
["R553","Cobalt synthesis","HOBYRNDA[c] + H2O[c] + ATP[c] + CO(II)[c] -> Pi[c] + ADP[c] + 3 H[c] + Co2ABYRDA[c]",null,null,"Cofactor and Prosthetic Group Biosynthesis","6.6.1.2"]
["R554","ATP:cob(I)yrinic acid-a,c-diamide Cobeta-adenosyltransferase","ATP[c] + CABYRDA[c]  -> TPi[c] + ADNS_CABYRDA[c] ","TT_P0002",null,"Cofactor and Prosthetic Group Biosynthesis","2.5.1.17"]
["R555","ATP:cobinamide Cobeta-adenosyltransferase","ATP[c] + H[c] + CBAMD[c]  <=> TPi[c] + ADNS_CBNA[c] ","TT_P0002",null,"Cofactor and Prosthetic Group Biosynthesis","2.5.1.17"]
["R556","adenosylcobyric acid:(R)-1-aminopropan-2-yl phosphate ligase","ATP[c] + ADNS_CABYRHA[c] + APRNPi[c]  -> ADP[c] + Pi[c] + ADNS_CBNAPi[c] ","TT_P0019",null,"Cofactor and Prosthetic Group Biosynthesis","6.3.1.10"]
["R557","cobalamin [5'-phosphate] synthase","ADNS_CBNA_GDP[c] + ARIBZ[c]  -> H[c] + GMP[c] + CBMCo[c] ","TT_P0004",null,"Cofactor and Prosthetic Group Biosynthesis","2.7.8.26"]
["R558","citrullinase","H2O[c] + H[c] + CTRLN[c]  -> ORT[c] + CO2[c] + NH4[c] ",null,null,"Arginine and Proline Metabolism","3.5.1.20"]
["R560","prephenate dehydratase","H[c] + PPHA[c]  -> H2O[c] + CO2[c] + PPYR[c] ",null,"pheA",null,"4.2.1.51"]
["R561","3-isopropylmalate dehydrogenase; beta-isopropylmalic enzyme; beta-isopropylmalate dehydrogenase; threo-Ds-3-isopropylmalate dehydrogenase; 3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase","H[c] + IPROP_OSUCC[c]  -> CO2[c] + 4M_2OPENTN[c] ","TTC0867","leuB","Valine, Leucine, and Isoleucine Metabolism","1.1.1.85"]
["R562","prephenate dehydrogenase (NADP+)","NADP[c] + PPHA[c]  <=> H[c] + CO2[c] + NADPH[c] + HYPh_PYR[c] ","TTC0447","tyrA","Tyrosine, Tryptophan, and Phenylalanine Metabolism","1.3.1.13"]
["R563","N2-acetyl-alpha-aminoadipate semialdehyde transaminase","L_GLU[c] + AC_AADP_SA[c]  -> AKG[c] + N2AC_L_LYS[c] ","TTC1393","lysJ","Threonine and Lysine Metabolism","2.6.1.-"]
["R564","alpha-aminoadipate acetyltransferase","ACoA[c] + AADP[c]  <=> CoA[c] + H[c] + AC_AADP[c] ","TTC1543","lysX","Threonine and Lysine Metabolism","6.3.2.-"]
["R565","methanogen homoaconitase","HCIT[c]  -> H2O[c] + HICTR[c] ","(TTC1546 and TTC1547)","lysTU","Threonine and Lysine Metabolism","4.2.1.114"]
["R566","CDP-diacylglycerol-serine O-phosphatidyltransferase","L_SER[c] + CDP_DAG[c]  -> H[c] + CMP[c] + PPTD_SER[c] ","TTC0824",null,"Membrane Lipid Metabolism","2.7.8.8"]
["R567","sulfite reductase (NADPH2)","5 H[c] + 3 NADPH[c] + SO3[c]  -> 3 NADP[c] + 3 H2O[c] + H2S[c] ","TTC0961",null,"Cysteine and methionine metabolism","1.8.2.2"]
["R568",null,"H2S[c] + 2 O2[c]  -> 2 H[c] + SO4[c] ",null,null,"Inorganic Ion Transport and Metabolism"]
["R569","catalase","2 H2O2[c]  -> 2 H2O[c] + O2[c] ","TTC1872",null,"Unassigned"]
["R570","cytochrome c oxidase","6 H[c] + 4 CYT_C2[c] + O2[c]  -> 2 H2O[c] + 6 H[e] + 4 CYT_C3[c] ","(TTC0769 and TTC0770 and TTC1671 and TTC1672)","cba","Oxidative Phosphorylation","1.9.3.1"]
["R571","trehalase","H2O[c] + TRE[c]  -> 2 D_GLC[c] ","TTC0614","treA","Alternate Carbon Metabolism","3.2.1.28"]
["R572","trehalose-6-phosphate hydrolase","H2O[c] + TRE6P[c]  -> D_GLC[c] + G6P[c] ","TTC0107","treC","Alternate Carbon Metabolism","3.2.1.93"]
["R573","trehalose-6-phosphate phosphatase","H2O[c] + TRE6P[c]  -> Pi[c] + TRE[c] ",null,"otsB","Alternate Carbon Metabolism","3.1.3.12"]
["R574","ATP synthase","ADP[c] + Pi[c] + 4 H[e]  <=> ATP[c] + H2O[c] + 3 H[c] ","(TTC0905 and TTC0906 and TTC0907 and TTC0908 and TTC0909 and TTC0910 and TTC0911 and TTC0912)",null,"Oxidative Phosphorylation","3.6.3.14"]
["R575","2-methylpropanoyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-(2-methylpropanoyl)transferase","CoA[c] + DHYLPL_MPROP_MPROP_DHLPL[c]  -> 2M_PROCoA[c] + ENZNE_DHYLPL[c] ","TTC1757","vorB","Valine, Leucine, and Isoleucine Metabolism","2.3.1.168"]
["R576","(S)-2-methylbutanoyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-(2-methylbutanoyl)transferase","CoA[c] + DHYLPL_MPROP_2MBUT_DHLPL[c]  -> MBUTNCoA[c] + ENZNE_DHYLPL[c] ","TTC1757","vorB","Valine, Leucine, and Isoleucine Metabolism","2.3.1.168"]
["R577","3-methylbutanoyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-(3-methylbutanoyl)transferase","CoA[c] + DHYLPL_MPROP_3MBUT_DHLPL[c]  -> ENZNE_DHYLPL[c] + IVCoA[c] ","TTC1757","vorB","Valine, Leucine, and Isoleucine Metabolism","2.3.1.168"]
["R578","dihydrolipoyl dehydrogenase","ENZNE_DHYLPL[c] + NAD[c] <=> ENZN6_LPL[c] + NADH[c] + H[c]","(TTC1700 or TTC1753)","lpdA","Valine, Leucine, and Isoleucine Metabolism","1.8.1.4"]
["R579","3-methylbutanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase","FAD[c] + IVCoA[c]  <=> FADH2[c] + MCROCoA[c] ","(TTC0238 or TTC0536 or TTC779 or TTC1552 or TTC1575 or TT_P0074)","atp","Valine, Leucine, and Isoleucine Metabolism","1.3.8.7"]
["R580","3-Methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)","ATP[c] + HCO3[c] + MCROCoA[c]  -> ADP[c] + Pi[c] + 3MGLUTNCoA[c] ","TTC1192","mccc1","Valine, Leucine, and Isoleucine Metabolism","6.4.1.4"]
["R581","(S)-3-Hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming)","H2O[c] + 3MGLUTNCoA[c]  -> HYM_GLUTRCoA[c] ","TTC0182",null,"Valine, Leucine, and Isoleucine Metabolism","4.2.1.18"]
["R582","succinyl-CoA:acetoacetate CoA-transferase","SUCCoA[c] + AAC[c]  <=> SUCC[c] + ACACoA[c] ",null,null,"Citric Acid Cycle","2.8.3.5"]
["R583","(S)-3-Hydroxyisobutyryl-CoA hydrolase","H2O[c] + HYIBUTRCoA[c]  <=> CoA[c] + HYIBUTRA[c] ",null,null,"Valine, Leucine, and Isoleucine Metabolism","3.1.2.4"]
["R584","(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase","NAD[c] + HY_MBUTRCoA[c]  -> H[c] + NADH[c] + MAACCoA[c] ","TTC0534",null,"Valine, Leucine, and Isoleucine Metabolism","1.1.1.35"]
["R585","Methylmalonyl-CoA epimerase","R_MMALCoA[c]  <=> MMALCoA[c] ","TTC0024",null,"Valine, Leucine, and Isoleucine Metabolism","5.1.99.1"]
["R586","biotin carboxyl carrier protein of acetyl-CoA carboxylase, acetyl-CoA carboxylase carboxyltransferase subunit alpha, acetyl-coenzyme A carboxylase carboxyl transferase subunit beta","ATP[c] + ACoA[c] + HCO3[c]  -> ADP[c] + Pi[c] + H[c] + MALCoA[c] ","(TTC1408 and TTC1409)",null,"Membrane Lipid Metabolism","6.4.1.2"]
["R587","phosphoribosylglycinamide formyltransferase","GAR[c] + 10F_THF[c]  <=> H[c] + FGAR[c] + THF[c] ","TTC0459",null,"Nucleotide Salvage Pathway","2.1.2.2"]
["R589","succinate dehydrogenase membrane anchor subunit","SUCC[c] + MQ[c]  <=> FUM[c] + MQL[c] ","TTC1089, TTC1090, TTC 1091, TTC1092",null,"Oxidative Phosphorylation","1.3.5.1"]
["R590","formate C-acetyltransferase","CoA[c] + PYR[c]  -> ACoA[c] + FOR[c] ",null,null,"Pyruvate Metabolism","2.3.1.54"]
["R591","protoporphyrinogen IX dehydrogenase (menaquinone)","3 MQ[c] + PPPHYRGN[c]  -> PPPHYR[c] + 3 MQL[c] ",null,null,"Cofactor and Prosthetic Group Biosynthesis","1.3.5.3"]
["R592","L-glutamate 5-semialdehyde dehydratase (spontaneous)","GLUT_SA[c]  <=> H2O[c] + H[c] + PYRR5CARB[c] ",null,null,"Arginine and Proline Metabolism","spontaneous"]
["R593","serine O-acetyltransferase","L_SER[c] + ACoA[c]  -> CoA[c] + OAC_SER[c] ","TTC1875","sat1","Cysteine and methionine metabolism","2.3.1.30"]
["R594","pyruvate dehydrogenase E1 component beta subunit","NAD[c] + CoA[c] + PYR[c]  -> NADH[c] + CO2[c] + ACoA[c] ","(TTC0568 and TTC1801 and TTC1802 and TTC1754 and TTC1753 and TTC1700)",null,"Glycolysis/Gluconeogenesis","1.2.1.-"]
["R595","acetaldehyde dehydrogenase","NAD[c] + CoA[c] + AALD[c]  <=> H[c] + NADH[c] + ACoA[c] ","TTC0604",null,"Pyruvate Metabolism","1.2.1.10"]
["R596","pyrimidine phosphatase","H2O[c] + APRIBTA_URA[c]  -> Pi[c] + 5AM_RIBAM_URA[c] ",null,null,"Cofactor and Prosthetic Group Biosynthesis","3.6.1.-"]
["R597","riboflavin synthase subunit alpha","2 DM_DR_LUM[c]  -> RBFLV[c] + 5AM_RIBAM_URA[c] ","TTC0698",null,"Cofactor and Prosthetic Group Biosynthesis","2.5.1.9"]
["R599","NADPH quinone reductase","H[c] + NADPH[c] + MQ[c]  -> NADP[c] + MQL[c] ",null,null,"Oxidative Phosphorylation","1.6.5.10"]
["R600","2-dehydropantoate 2-reductase","H[c] + NADPH[c] + DHY_PAN[c]  -> NADP[c] + PANTA[c] ",null,null,"Cofactor and Prosthetic Group Biosynthesis","1.1.1.169"]
["R601","adenine phosphoribosyltransferase","PRPP[c] + ADN[c]  -> PPi[c] + AMP[c] ","(TTC1249 or TTC1250)",null,"Nucleotide Salvage Pathway","2.4.2.7"]
["R602","cobalamin [5'-phosphate] synthase","H[c] + PRIBS_DMBENZ_IMDZ[c] + ADNS_CBNA_GDP[c]  -> GMP[c] + CBMCo[c] ","TT_P0004 ",null,"Nucleotide Salvage Pathway","2.7.8.26"]
["R603","GMP synthase","L_GLN[c] + ATP[c] + H2O[c] + XMP[c]  -> L_GLU[c] + PPi[c] + 2 H[c] + AMP[c] + GMP[c] ","(TTC0355 or TTC1187)",null,"Nucleotide Salvage Pathway","6.3.5.2"]
["R604",null,"L_GLN[c] + ATP[c] + H2O[c] + XMP[c]  -> L_GLU[c] + L_ASN[c] + PPi[c] + H[c] + AMP[c] ",null,null,"Nucleotide Salvage Pathway"]
["R605","GTP cyclohydrolase I","GTP[c] + H2O[c]  -> H[c] + FOR[c] + AHYRY_THYPROP_DHYPTRN_TPi[c] ","TTC1517",null,"Nucleotide Salvage Pathway","3.5.4.16"]
["R606","mannose-1-phosphate guanylyltransferase","GTP[c] + H[c] + MAN1P[c]  -> PPi[c] + GDP_MAN[c] ","TTC1388",null,"Alternate Carbon Metabolism","2.7.7.13"]
["R607","GTPase","GTP[c] + H2O[c]  <=> Pi[c] + H[c] + GDP[c] ","TTC1158",null,"Nucleotide Salvage Pathway","3.6.5.-"]
["R608","phosphoribosylaminoimidazole carboxylase","CO2[c] + AIR[c]  -> 2 H[c] + CAIR[c] ","(TTC0137 and TTC0138)",null,"Nucleotide Salvage Pathway","4.1.1.21"]
["R609","adenosylcobinamide-phosphate synthase","ATP[c] + ADNS_CABYRHA[c] + A_PROPOL[c]  <=> ADP[c] + Pi[c] + H[c] + ADNS_CBNAPi[c] ","TT_P0019",null,"Cofactor and Prosthetic Group Biosynthesis","6.3.1.10"]
["R610","2-keto-3-deoxy-gluconate kinase","ATP[c] + 2K3DO_GLCN[c]  -> ADP[c] + H[c] + DHY_DOP_GLUCN[c] ","TT_P0036",null,"Alternate Carbon Metabolism","2.7.1.45"]
["R611","2-phosphoglycerate kinase","ATP[c] + D_GLCT[c]  -> ADP[c] + H[c] + 2PG[c] ","TTC0121",null,"Glycine and Serine Metabolism","2.7.1.165"]
["R612","Propionate-CoA ligase","ATP[c] + CoA[c] + PROP[c]  -> PPi[c] + AMP[c] + PRCoA[c] ","TTC0884",null,"Valine, Leucine, and Isoleucine Metabolism","6.2.1.17"]
["R613","NH(3)-dependent NAD(+) synthetase","L_GLN[c] + ATP[c] + H2O[c] + DA_NAD[c]  -> L_GLU[c] + NAD[c] + PPi[c] + H[c] + AMP[c] ","TTC1538",null,"Cofactor and Prosthetic Group Biosynthesis","6.3.5.1"]
["R614","NAD+ kinase","ATP[c] + NAD[c]  -> NADP[c] + ADP[c] + H[c] ",null,null,"Cofactor and Prosthetic Group Biosynthesis","2.7.1.23"]
["R615","acid phosphatase","NADP[c] + H2O[c]  -> NAD[c] + Pi[c] ","TTC1252",null,"Cofactor and Prosthetic Group Biosynthesis","3.1.3.2"]
["R616","thymidine kinase","ATP[c] + THYMD[c]  -> ADP[c] + H[c] + dTMP[c] ",null,null,"Nucleotide Salvage Pathway","2.7.1.21"]
["R617","adenylyl-sulfate kinase","ATP[c] + APS[c]  -> ADP[c] + H[c] + PAPS[c] ","TTC0307",null,"Cysteine and methionine metabolism","2.7.1.25"]
["R618","urea carboxylase/allophanate hydrolase","ATP[c] + H2O[c] + CO2[c] + UREA[c]  -> ADP[c] + Pi[c] + 2 H[c] + UREA_CARB[c] ","TTC0624",null,"Arginine and Proline Metabolism","6.3.4.6"]
["R619","carbamate kinase","ADP[c] + H[c] + CARB_Pi[c]  -> ATP[c] + CO2[c] + NH4[c] ",null,null,"Unassigned","2.7.2.2"]
["R620","acetate kinase","ADP[c] + ACPi[c]  -> ATP[c] + AC[c] ","TTC0137",null,"Pyruvate Metabolism","2.7.2.1"]
["R621","phosphoenolpyruvate carboxylase","PEP[c] + HCO3[c]  <=> Pi[c] + OAC[c] ","TTC0260",null,"Glycolysis/Gluconeogenesis","4.1.1.31"]
["R622","dihydroorotate dehydrogenase (quinone)","MQ[c] + DHY_ORTA[c]  -> MQL[c] + ORTA[c] ","TTC0424",null,"Nucleotide Salvage Pathway","1.3.5.2"]
["R623","NAD+ diphosphatase","NAD[c] + H2O[c]  -> 2 H[c] + AMP[c] + NMN[c] ","TTC0964",null,"Cofactor and Prosthetic Group Biosynthesis","3.6.1.22"]
["R624","NMN nucleosidase","H2O[c] + NMN[c]  -> H[c] + R5P[c] + NAMD[c] ",null,null,"Cofactor and Prosthetic Group Biosynthesis","3.2.2.14"]
["R625","nicotinamidase","H2O[c] + NAMD[c]  -> NH4[c] + NIA[c] ","TTC1446",null,"Cofactor and Prosthetic Group Biosynthesis","3.5.1.19"]
["R626","nicotinamide-nucleotide amidase","H2O[c] + NMN[c]  -> H[c] + NH4[c] + NC_D_RNUC[c] ","TTC1468",null,"Cofactor and Prosthetic Group Biosynthesis","3.5.1.42"]
["R627","nicotinate-nucleotide adenylyltransferase","ATP[c] + H[c] + NC_D_RNUC[c]  <=> PPi[c] + DA_NAD[c] ","TTC1421",null,"Cofactor and Prosthetic Group Biosynthesis","2.7.7.18"]
["R628","NAD+ nucleosidase","NAD[c] + H2O[c]  -> H[c] + ADP_RIB[c] + NAMD[c] ",null,null,"Cofactor and Prosthetic Group Biosynthesis","3.2.2.5"]
["R629","thiosulfate sulfurtransferase","R_TRED[c] + TSFA[c]  <=> H[c] + O_TRED[c] + H2S[c] + SO3[c] ","(TTC0666 or TTC1258 or TTC0155)",null,"Cofactor and Prosthetic Group Biosynthesis","2.8.1.-"]
["R630","formate dehydrogenase","CO2[c] + NADPH[c] + H[c] <=> FOR[c] + NADP[c]","TT_P0138",null,"Cofactor and Prosthetic Group Biosynthesis","1.2.1.43/1.2.1.2"]
["R631","formate-tetrahydrofolate ligase","ATP[c] + THF[c] + FOR[c]  -> ADP[c] + Pi[c] + FOLNA[c] ","TTC1707",null,"Cofactor and Prosthetic Group Biosynthesis","6.3.4.3"]
["R632","dihydrofolate reductase","H[c] + NADPH[c] + DHF[c]  -> NADP[c] + THF[c] ",null,null,"Cofactor and Prosthetic Group Biosynthesis","1.5.1.3"]
["R633","2-oxoacid-ferredoxin oxidoreductase","CO2[c] + PRCoA[c] + R_FRDX[c]  -> CoA[c] + AKB[c] + O_FRDX[c] ","TTC1591",null,"Cofactor and Prosthetic Group Biosynthesis","1.2.7.2"]
["R634","methylenetetrahydrofolate reductase (ferredoxin)","2 H[c] + 5_10_MNTHF[c] + 2 R_FRDX[c]  -> 5MTHF[c] + 2 O_FRDX[c] ","TTC1656",null,"Cofactor and Prosthetic Group Biosynthesis","1.5.7.1"]
["R635","nitrilotriacetate monooxygenase component B, NADH-dependent flavin oxidoreductase","H[c] + NADH[c] + FMN[c]  <=> NAD[c] + FMNH2[c] ","(TTC0052 or TTC1829)",null,"Cofactor and Prosthetic Group Biosynthesis","1.14.13.-"]
["R636","thymidylate synthase","dUMP[c] + 5_10_MNTHF[c]  <=> dTMP[c] + DHF[c] ",null,null,"Nucleotide Salvage Pathway","2.1.1.45"]
["R637","uridine nucleosidase","H2O[c] + URD[c]  -> D_RIB[c] + URA[c] ",null,null,"Nucleotide Salvage Pathway","3.2.2.3"]
["R638","uridine phosphorylase","Pi[c] + URD[c]  -> R1P[c] + URA[c] ","TTC1070",null,"Nucleotide Salvage Pathway","2.4.2.3"]
["R639","cob(II)yrinic acid a,c-diamide reductase","FMNH2[c] + 2 Co2ABYRDA[c]  -> 3 H[c] + FMN[c] + 2 CABYRDA[c] ","TT_P0018 ",null,"Cofactor and Prosthetic Group Biosynthesis","1.16.8.1"]
["R640","adenosylcobinamide-phosphate guanylyltransferase","GTP[c] + H[c] + ADNS_CBNAPi[c]  -> PPi[c] + ADNS_CBNA_GDP[c] ","TT_P0023 ",null,"Cofactor and Prosthetic Group Biosynthesis","2.7.7.62"]
["R641","aminodeoxychorismate synthase","L_GLN[c] + CORM[c]  -> L_GLU[c] + 4A4CORM[c] ","TTC0355 ",null,"Cofactor and Prosthetic Group Biosynthesis","2.6.1.85"]
["R642","4-amino-4-deoxychorismate lyase","4A4CORM[c]  -> H[c] + PYR[c] + ABEE[c] ","TTC1477",null,"Cofactor and Prosthetic Group Biosynthesis","4.1.3.38"]
["R643","putative deoxyribonucleotide triphosphate pyrophosphatase","UTP[c] + H2O[c]  -> Pi[c] + H[c] + UDP[c] ","TTC1290",null,"Nucleotide Salvage Pathway","3.6.1.15"]
["R644","nucleoside-diphosphatase","H2O[c] + UDP[c]  -> Pi[c] + H[c] + UMP[c] ",null,null,"Nucleotide Salvage Pathway","3.6.1.6"]
["R645","apyrase","CTP[c] + 2 H2O[c]  -> 2 Pi[c] + 2 H[c] + CMP[c] ",null,null,"Nucleotide Salvage Pathway","3.6.1.5"]
["R646","putative deoxyribonucleotide triphosphate pyrophosphatase","CTP[c] + H2O[c]  -> Pi[c] + H[c] + CDP[c] ","TTC1290",null,"Nucleotide Salvage Pathway","3.6.1.15"]
["R647","nucleoside-diphosphatase","H2O[c] + CDP[c]  -> Pi[c] + H[c] + CMP[c] ",null,null,"Nucleotide Salvage Pathway","3.6.1.6"]
["R648","ornithine aminotransferase","ORT[c] + AKG[c]  -> L_GLU[c] + GLU_SA[c] ","TTC0553",null,"Arginine and Proline Metabolism","2.6.1.13"]
["R649","formate hydrogenlyase","FOR[c]  -> 2 H[c] + CO2[c] ",null,null,"Pyruvate Metabolism"]
["R650","phosphoserine aminotransferase","L_GLU[c] + 3POXPYR[c]  -> AKG[c] + PPTD_SER[c] ",null,"serC","Glycine and Serine Metabolism","2.6.1.52"]
["R651","3-phosphoserine phosphatase","H2O[c] + PPTD_SER[c]  -> L_SER[c] + Pi[c] ",null,"serB","Glycine and Serine Metabolism","3.1.3.3"]
["R652","valine-pyruvate aminotransferase","L_VAL[c] + PYR[c]  -> L_ALA[c] + 2K3M_BUT[c] ","TTC1960",null,"Valine, Leucine, and Isoleucine Metabolism","2.6.1.66"]
["R653","coproporphyrinogen oxidase","2 H[c] + O2[c] + CPPPHYRGN[c]  -> 2 H2O[c] + 2 CO2[c] + PPPHYRGN[c] ",null,null,"Cofactor and Prosthetic Group Biosynthesis","1.3.3.3"]
["R654","quinate/shikimate dehydrogenase","H[c] + NADH[c] + DHY_SHK[c]  -> NAD[c] + SHK[c] ","TTC0688 ","ydiB","Tyrosine, Tryptophan, and Phenylalanine Metabolism","1.1.1.282"]
["R655","serine hydroxymethyltransferase","L_SER[c] + THF[c]  -> L_GLY[c] + H2O[c] + METHF[c] ","TTC1160",null,"Glycine and Serine Metabolism","2.1.2.1"]
["R656","serine-glyoxylate transaminase","L_SER[c] + GLOXT[c]  -> L_GLY[c] + HY_PYR[c] ",null,"sgaA","Glycine and Serine Metabolism","2.6.1.45"]
["R657","malate-CoA ligase","ATP[c] + CoA[c] + MAL[c]  -> ADP[c] + Pi[c] + MALYCoA[c] ",null,null,"Glycine and Serine Metabolism","6.2.1.9"]
["R658","malyl-CoA lyase","MALYCoA[c]  -> ACoA[c] + GLOXT[c] ",null,null,"Glycine and Serine Metabolism","4.1.3.24"]
["R659","acyl-CoA hydrolase","2 H2O[c] + ACoA[c]  -> CoA[c] + 5 H[c] + GLOXT[c] ","TTC1452 ",null,"Glycine and Serine Metabolism","3.1.2.20 "]
["R660","malate dehydrogenase","NADP[c] + MAL[c]  -> PYR[c] + CO2[c] + NADPH[c] ","TTC0144",null,"Anaplerotic Reactions","1.1.1.40"]
["R661","fructose 1,6-bisphosphatase II ","H2O[c] + FBP[c]  -> Pi[c] + F6P[c] ","TTC1081",null,"Glycolysis/Gluconeogenesis","3.1.3.11"]
["R662","glucose-1-phosphatase","H2O[c] + G1P[c]  -> Pi[c] + D_GLC[c] ",null,"agp","Glycolysis/Gluconeogenesis","3.1.3.10"]
["R663","phosphate acetyltransferase","Pi[c] + ACoA[c]  -> CoA[c] + ACPi[c] ",null,"pta","Pyruvate Metabolism","2.3.1.8"]
["R664","acetolactate synthase large subunit","H[c] + PYR[c] + AKB[c]  -> CO2[c] + AC_HYBUTNA[c] ","TTC0852","ilvB","Valine, Leucine, and Isoleucine Metabolism","2.2.1.6"]
["R665","ketol-acid reductoisomerase","H[c] + NADPH[c] + AC_HYBUTNA[c]  -> NADP[c] + DHY_MPENTA[c] ","TTC0850","ilvC","Valine, Leucine, and Isoleucine Metabolism","1.1.1.86"]
["R666","2-oxoglutarate ferredoxin oxidoreductase subunit beta","CoA[c] + AKG[c] + 2 O_FRDX[c]  <=> CO2[c] + SUCCoA[c] + 2 R_FRDX[c] ","TTC1592",null,"Citric Acid Cycle","1.2.7.3"]
["R667","fatty acid synthesis; lumped","16 H[c] + 11 NADPH[c] + 6 MALCoA[c] + MBUTNCoA[c]  -> 7 CoA[c] + 11 NADP[c] + AI171[c] + 5 H2O[c] + 6 CO2[c] ","((TTC0049 or TTC0045) and (TTC0045 or (TTC0049 or TTC0343)) and (TTC0047 or TTC0394) and TTC1463 and TTC0048)","FabF, FabG, FabI, FabZ","Membrane Lipid Metabolism","2.3.1.180 and (2.3.1.179 or 2.3.1.180) and 1.1.1.100 and 4.2.1.59"]
["R668","fatty acid synthesis; lumped","14 H[c] + 10 NADPH[c] + 5 MALCoA[c] + MBUTNCoA[c]  -> 6 CoA[c] + 10 NADP[c] + AI150[c] + 4 H2O[c] + 5 CO2[c] ","((TTC0049 or TTC0045) and (TTC0045 or (TTC0049 or TTC0343)) and (TTC0047 or TTC0394) and TTC1463 and TTC0048)","FabF, FabG, FabI, FabZ","Membrane Lipid Metabolism","2.3.1.180 and (2.3.1.179 or 2.3.1.180) and 1.1.1.100 and 4.2.1.59"]
["R669","fatty acid synthesis; lumped","14 H[c] + 10 NADPH[c] + 5 MALCoA[c] + IVCoA[c]  -> 6 CoA[c] + 10 NADP[c] + I150[c] + 4 H2O[c] + 5 CO2[c] ","((TTC0049 or TTC0045) and (TTC0045 or (TTC0049 or TTC0343)) and (TTC0047 or TTC0394) and TTC1463 and TTC0048)","FabF, FabG, FabI, FabZ","Membrane Lipid Metabolism","2.3.1.180 and (2.3.1.179 or 2.3.1.180) and 1.1.1.100 and 4.2.1.59"]
["R670","fatty acid synthesis; lumped","17 H[c] + 12 NADPH[c] + 6 MALCoA[c] + 2M_PROCoA[c]  -> 7 CoA[c] + 12 NADP[c] + I160[c] + 5 H2O[c] + 6 CO2[c] ","((TTC0049 or TTC0045) and (TTC0045 or (TTC0049 or TTC0343)) and (TTC0047 or TTC0394) and TTC1463 and TTC0048)","FabF, FabG, FabI, FabZ","Membrane Lipid Metabolism","2.3.1.180 and (2.3.1.179 or 2.3.1.180) and 1.1.1.100 and 4.2.1.59"]
["R671","fatty acid synthesis; lumped","16 H[c] + 12 NADPH[c] + 6 MALCoA[c] + IVCoA[c]  -> 7 CoA[c] + 12 NADP[c] + I170[c] + 5 H2O[c] + 6 CO2[c] ","((TTC0049 or TTC0045) and (TTC0045 or (TTC0049 or TTC0343)) and (TTC0047 or TTC0394) and TTC1463 and TTC0048)","FabF, FabG, FabI, FabZ","Membrane Lipid Metabolism","2.3.1.180 and (2.3.1.179 or 2.3.1.180) and 1.1.1.100 and 4.2.1.59"]
["R672","fatty acid synthesis; lumped","12 H[c] + 8 NADPH[c] + 4 MALCoA[c] + IVCoA[c]  -> 5 CoA[c] + 8 NADP[c] + I130[c] + 3 H2O[c] + 4 CO2[c] ","((TTC0049 or TTC0045) and (TTC0045 or (TTC0049 or TTC0343)) and (TTC0047 or TTC0394) and TTC1463 and TTC0048)","FabF, FabG, FabI, FabZ","Membrane Lipid Metabolism","2.3.1.180 and (2.3.1.179 or 2.3.1.180) and 1.1.1.100 and 4.2.1.59"]
["R673","fatty acid synthesis; lumped","10 H[c] + 6 NADPH[c] + 3 MALCoA[c] + IVCoA[c]  -> 6 CoA[c] + 6 NADP[c] + I110[c] + 2 H2O[c] + 3 CO2[c] ","((TTC0049 or TTC0045) and (TTC0045 or (TTC0049 or TTC0343)) and (TTC0047 or TTC0394) and TTC1463 and TTC0048)","FabF, FabG, FabI, FabZ","Membrane Lipid Metabolism","2.3.1.180 and (2.3.1.179 or 2.3.1.180) and 1.1.1.100 and 4.2.1.59"]
["R674","fatty acid synthesis; lumped","20 H[c] + ACoA[c] + 14 NADPH[c] + 7 MALCoA[c]  -> 8 CoA[c] + 14 NADP[c] + C160[c] + 6 H2O[c] + 7 CO2[c] ","((TTC0049 or TTC0045) and (TTC0045 or (TTC0049 or TTC0343)) and (TTC0047 or TTC0394) and TTC1463 and TTC0048 and TTC1678)","FabF, FabG, FabI, FabZ","Membrane Lipid Metabolism","2.3.1.180 and (2.3.1.179 or 2.3.1.180) and 1.1.1.100 and 4.2.1.59"]
["R675","fatty acid synthesis; lumped","21 H[c] + ACoA[c] + 15 NADPH[c] + 7 MALCoA[c] + O2[c]  -> 8 CoA[c] + 15 NADP[c] + C161[c] + 6 H2O[c] + 7 CO2[c] ","((TTC0049 or TTC0045) and (TTC0045 or (TTC0049 or TTC0343)) and (TTC0047 or TTC0394) and TTC1463 and (TTC0238 or TTC0536 or TTC779 or TTC1552 or TTC1575 or TT_P0074) and TTC0048  and TTC1678)","FabF, FabG, FabI, FabZ","Membrane Lipid Metabolism","2.3.1.180 and (2.3.1.179 or 2.3.1.180) and 1.1.1.100 and 4.2.1.59"]
["R676","fatty acid oxidation; lumped","7 CoA[c] + 7 H2O[c] + C161CoA[c] + 7 NAD[c] + NADPH[c] + 7 O2[c] -> 8 ACoA[c] + 6 H[c] + 7 H2O2[c] + 7 NADH[c] + NADP[c]","((TTC0236 or TTC0342) and (TT_P0074 or TTC0238 or TTC0536) and (TTC0604 or TTC1697 or TTC1768) and (TTC0331 or TTC0534) and (TTC0623 or TTC0535))",null,"Membrane Lipid Metabolism","1.3.8.- and 4.2.1.17 and 1.1.1.35 and 2.3.1.16"]
["R677","fatty acid oxidation; lumped","7 CoA[c] + 7 H2O[c] + C161CoA[c] + 7 NAD[c] + 6 O2[c] -> 8 ACoA[c] + 7 H[c] + 6 H2O2[c] + 7 NADH[c]","((TTC0236 or TTC0342) and (TT_P0074 or TTC0238 or TTC0536) and (TTC0604 or TTC1697 or TTC1768) and (TTC0331 or TTC0534) and (TTC0623 or TTC0535))",null,"Membrane Lipid Metabolism","1.3.8.- and 4.2.1.17 and 1.1.1.35 and 2.3.1.16"]
["R678","fatty acid coA--ligase","ATP[c] + CoA[c] + AI171[c] <=> AMP[c] + AI171CoA[c] + PPi[c]","(TTC0079 or TTC1065 or TTC1099)",null,"Membrane Lipid Metabolism","6.2.1.3"]
["R679","fatty acid coA--ligase","ATP[c] + CoA[c] + AI150[c] <=> AMP[c] + AI150CoA[c] + PPi[c]","(TTC0079 or TTC1065 or TTC1099)",null,"Membrane Lipid Metabolism","6.2.1.3"]
["R680","fatty acid coA--ligase","ATP[c] + CoA[c] + I150[c] <=> AMP[c] + I150CoA[c] + PPi[c]","(TTC0079 or TTC1065 or TTC1099)",null,"Membrane Lipid Metabolism","6.2.1.3"]
["R681","fatty acid coA--ligase","ATP[c] + CoA[c] + I160[c] <=> AMP[c] + I160CoA[c] + PPi[c]","(TTC0079 or TTC1065 or TTC1099)",null,"Membrane Lipid Metabolism","6.2.1.3"]
["R682","fatty acid coA--ligase","ATP[c] + CoA[c] + I170[c] <=> AMP[c] + I170CoA[c] + PPi[c]","(TTC0079 or TTC1065 or TTC1099)",null,"Membrane Lipid Metabolism","6.2.1.3"]
["R683","fatty acid coA--ligase","ATP[c] + CoA[c] + C160[c] <=> AMP[c] + C160CoA[c] + PPi[c]","(TTC0079 or TTC1065 or TTC1099)",null,"Membrane Lipid Metabolism","6.2.1.3"]
["R684","fatty acid coA--ligase","ATP[c] + CoA[c] + C161[c] <=> AMP[c] + C161CoA[c] + PPi[c]","(TTC0079 or TTC1065 or TTC1099)",null,"Membrane Lipid Metabolism","6.2.1.3"]
["R685","lycopene epsilon-cyclase","LCPN[c]  <=> gCARO[c] ",null,"crtY","Carotenoid biosynthesis","5.5.1.18"]
["R686","lycopene beta-cyclase","gCARO[c]  <=> bCARO[c] ",null,"crtY","Carotenoid biosynthesis","5.5.1.18"]
["R687","UTP--glucose-1-phosphate uridylyltransferase","G1P[c] + UTP[c] + H[c] <=> UDP_GLU[c] + PPi[c]",null,null,"Alternate Carbon Metabolism"]
["R688","beta-carotene hydroxylase","H[c] + NADH[c] + O2[c] + bCARO[c]  <=> NAD[c] + H2O[c] + CRTX[c] ","TT_P0059","crtZ","Carotenoid biosynthesis"]
["R689","beta-cryptoxanthin hydroxylase ","H[c] + NADH[c] + O2[c] + CRTX[c]  -> NAD[c] + ZXT[c] + H2O[c] ","TT_P0059","crtZ","Carotenoid biosynthesis"]
["R690","thermocryptoxanthin hydroxylase ","H[c] + NADH[c] + O2[c] + tCRTX[c]  -> NAD[c] + tZXT[c] + H2O[c] ","TT_P0059","crtZ","Carotenoid biosynthesis"]
["R691","beta-cryptoxanthin glucosyltransferase","CRTX[c] + UDP_GLU[c]  -> bCRTX_GLU[c] + UDP[c] +  H[c] ","TT_P0062","crtQ","Carotenoid biosynthesis"]
["R692","beta-cryptoxanthin acyltransferase (C11:0)","bCRTX_GLU[c] + 0.334 I150CoA[c] + 0.069 AI150CoA[c] + 0.047 I160CoA[c] + 0.014 C160CoA[c] + 0.0015 C161CoA[c] + 0.45 I170CoA[c] + 0.075 AI171CoA[c] -> tCRTX[c] + CoA[c] ","TT_P0061","orf-AT","Carotenoid biosynthesis"]
["R693","zeaxanthin glucosyltransferase","ZXT[c] + UDP_GLU[c]  -> ZXT_GLU[c] + UDP[c] +  H[c] ","TT_P0062","crtQ","Carotenoid biosynthesis"]
["R694","zeaxanthin acyltransferase (C13:0)","ZXT_GLU[c] + 0.334 I150CoA[c] + 0.069 AI150CoA[c] + 0.047 I160CoA[c] + 0.014 C160CoA[c] + 0.0015 C161CoA[c] + 0.45 I170CoA[c] + 0.075 AI171CoA[c]  -> tZXT[c] + CoA[c] ","TT_P0061","orf-AT","Carotenoid biosynthesis"]
["R695","thermozeaxanthin glucosyltransferase","tZXT[c] + UDP_GLU[c]  -> tZXT_GLU[c] + UDP[c] +  H[c] ","TT_P0062","crtQ","Carotenoid biosynthesis"]
["R696","thermozeaxanthin acyltransferase (C13-C13)","tZXT_GLU[c] + 0.334 I150CoA[c] + 0.069 AI150CoA[c] + 0.047 I160CoA[c] + 0.014 C160CoA[c] + 0.0015 C161CoA[c] + 0.45 I170CoA[c] + 0.075 AI171CoA[c]  -> tbZXT[c] + CoA[c] ","TT_P0061","orf-AT","Carotenoid biosynthesis"]
["R697","glucosamine-6-phosphate deaminase","H2O[c] + GLUSAP[c]  -> F6P[c] + NH4[c] ","TTC1074",null,null,"3.5.99.6"]
["R698","acetyl-CoA C-acetyltransferase","2 ACoA[c] -> CoA[c] + ACACoA[c]","(TTC0191 or TTC0330)",null,"Butanoate metabolism","2.3.1.9"]
["R699","(R)-3-Hydroxybutanoyl-CoA:NADP+ oxidoreductase","H[c] + NADPH[c] + ACACoA[c]  <=> NADP[c] + RHY_BUTCoA[c] ","TTC0898",null,"Butanoate metabolism","1.1.1.157"]
["R700","beta-ketothiolase ","ACoA[c] + PRCoA[c]  -> CoA[c] + KVCoA[c] ","(TTC0191 or TTC0330 or TTC0525 or TTC0623)",null,"Butanoate metabolism"]
["R701","(R)-3-Hydroxybutanoyl-CoA:NADP+ oxidoreductase","3 H[c] + NADPH[c] + KVCoA[c]  <=> NADP[c] + HVCoA[c] ","TTC0898",null,"Butanoate metabolism"]
["R702","Acyltransferase","2 RHY_BUTCoA[c]  -> 2 CoA[c] + PHB[c] ",null,null,"Butanoate metabolism","2.3.1.-"]
["R703","Acyltransferase","2 HVCoA[c]  -> CoA[c] + PHV[c] ",null,null,"Butanoate metabolism"]
["R704","fatty acid synthesis; lumped","RHY_BUTCoA[c] + 2 ACoA[c] + 4 NADPH[c] + 4 H[c]  <=> 4 NADP[c] + HY_OCTCoA[c] + 2 H2O[c] + 2 CoA[c]","((TTC0049 or TTC0045) and (TTC0045 or (TTC0049 or TTC0343)) and (TTC0047 or TTC0394) and TTC1463 and TTC0048 and TTC1678)",null,"Butanoate metabolism"]
["R705","Acyltransferase","2 HY_OCTCoA[c]  -> 2 CoA[c] + PHO[c] ",null,null,"Butanoate metabolism"]
["R706","fatty acid synthesis; lumped","HY_OCTCoA[c] + ACoA[c] + 2 NADPH[c] + 2 H[c]  <=> 2 NADP[c] + HY_DECCoA[c] + H2O[c] + CoA[c]","((TTC0049 or TTC0045) and (TTC0045 or (TTC0049 or TTC0343)) and (TTC0047 or TTC0394) and TTC1463 and TTC0048 and TTC1678)",null,"Butanoate metabolism"]
["R707","Acyltransferase","2 HY_DECCoA[c]  -> 2 CoA[c] + PHD[c] ",null,null,"Butanoate metabolism"]
["R708","fatty acid synthesis; lumped","HY_DECCoA[c] + ACoA[c] + 2 NADPH[c] + 2 H[c]  <=> 2 NADP[c] + HY_DODECCoA[c] + H2O[c] + CoA[c]","((TTC0049 or TTC0045) and (TTC0045 or (TTC0049 or TTC0343)) and (TTC0047 or TTC0394) and TTC1463 and TTC0048 and TTC1678)",null,"Butanoate metabolism"]
["R709","Acyltransferase","2 HY_DODECCoA[c]  -> 2 CoA[c] + PHDD[c] ",null,null,"Butanoate metabolism"]
["R710","gluconokinase","ATP[c] + GLCN[c]  -> ADP[c] + H[c] + GLCN6P[c] ",null,null,"Pentose Phosphate Pathway","2.7.1.12"]
["R711","gluconate 5-dehydrogenase (NAD+)","H[c] + NADH[c] + DHYGLCN[c]  -> NAD[c] + GLCN[c] ","TTC0235",null,null,"1.1.1.69"]
["R712","gluconate 5-dehydrogenase (NADP+)","H[c] + NADPH[c] + DHYGLCN[c]  -> NADP[c] + GLCN[c] ","TTC0235",null,null,"1.1.1.69"]
["R713","gluconolactonase","H2O[c] + GLC_LACN[c]  -> H[c] + GLCN[c] ",null,null,"Pentose Phosphate Pathway","3.1.1.17"]
["R714","phosphogluconate dehydratase","GLCN6P[c]  -> H2O[c] + DHY_DOP_GLUCN[c] ","TTC0871",null,"Pentose Phosphate Pathway","4.2.1.12"]
["R715","NADH:ubiquinone oxidoreductase I","H[c] + NADH[c] + MQ[c]  -> NAD[c] + MQL[c] ",null,null,"Oxidative Phosphorylation","1.6.5.-"]
["R716","S-adenosylmethionine decarboxylase","SAM[c] + H[c]  -> dcSAM[c] + CO2[c] ","TTC0473"]
["R717","spermine synthase","AGMT[c] + dcSAM[c]  -> apAGMT[c] + MTA[c] + H[c] ","TTC0472"]
["R718","agmatinase","apAGMT[c] + H2O[c]  -> SPRD[c] + UREA[c] ","TTC0764"]
["R719","S-adenosylmethioninamine:spermidine 3-aminopropyltransferase","dcSAM[c] + SPRD[c]  -> H[c] + MTA[c] + SPR[c] ","TTC0472"]
["R720","S-adenosylmethioninamine:spermidine 3-aminopropyltransferase","dcSAM[c] + SPRD[c]  -> H[c] + MTA[c] + tSPR[c] ","TTC0472"]
["R721","polyamine synthesis; lumped","2 dcSAM[c] + SPRD[c]  -> 2 H[c] + 2 MTA[c] + tPAM[c] "]
["R722","polyamine synthesis; lumped","2 dcSAM[c] + SPRD[c]  -> 2 H[c] + 2 MTA[c] + hCPAM[c] "]
["R723","polyamine synthesis; lumped","3 dcSAM[c] + SPRD[c]  -> 3 H[c] + 3 MTA[c] + hCHAM[c] "]
["R724","polyamine synthesis; lumped","dcSAM[c] + PDAM[c]  -> H[c] + MTA[c] + NSPRD[c] "]
["R725","polyamine synthesis; lumped","2 dcSAM[c] + PDAM[c]  -> 2 H[c] + 2 MTA[c] + TM[c] "]
["R726","polyamine synthesis; lumped","3 dcSAM[c] + PDAM[c]  -> 3 H[c] + 3 MTA[c] + CPAM[c] "]
["R727","polyamine synthesis; lumped","4 dcSAM[c] + PDAM[c]  -> 4 H[c] + 4 MTA[c] + CHAM[c] "]
["R728","polyamine synthesis; lumped","2 dcSAM[c] + PDAM[c]  -> 3 H[c] + 2 MTA[c] + TRIAM[c] "]
["R729","polyamine synthesis; lumped","3 dcSAM[c] + PDAM[c]  -> 3 H[c] + 3 MTA[c] + TETAM[c] "]
["R730","polyamine synthesis; lumped","PUT[c] + SPRD[c]  -> hSPRD[c] + PDAM[c] "]
["R731","polyamine synthesis; lumped","2 SPRD[c]  -> hSPR[c] + PDAM[c] "]
["R732","Glucose transport via ABC transporter","ATP[c] + H2O[c] + D_GLC[e]  -> ADP[c] + D_GLC[c] + H[c] + Pi[c] ","((TTC0326 or TTC0327) and TTC0328)",null,"Transport, Extracellular"]
["R733","Water transport","H2O[e]  <=> H2O[c] ",null,null,"Transport, Extracellular"]
["R734","Oxygen transport","O2[e]  -> O2[c] ",null,null,"Transport, Extracellular"]
["R735","Sulfate transport","SO4[e]  -> SO4[c] ",null,null,"Transport, Extracellular"]
["R736","Phosphate transport","H[e] + Pi[e]  <=> Pi[c] + H[c] ","(TTC1724 and TTC1725)",null,"Transport, Extracellular"]
["R737","Carbon dioxide transport","CO2[c]  <=> CO2[e] ",null,null,"Transport, Extracellular"]
["R738","Acetate transport","AC[e]  <=> AC[c] ",null,null,"Transport, Extracellular"]
["R739","D-Alanyl-D-alanine transport via ABC system","D_ALA_D_ALA[e]  <=> D_ALA_D_ALA[c] ","((TTC1270 or TTC0972) and TTC0973)",null,"Transport, Extracellular"]
["R740","L-Arginine transport","L_ARG[e]  <=> L_ARG[c]",null,null,"Transport, Extracellular"]
["R741","L-Asparagine transport","L_ASN[e]  <=> L_ASN[c]",null,null,"Transport, Extracellular"]
["R742","Citrate transport","CIT[e]  <=> CIT[c] ",null,null,"Transport, Extracellular"]
["R743","Ethanol transport","ETH[e]  <=> ETH[c] ",null,null,"Transport, Extracellular"]
["R744","D-Fructose 1-phosphate transport","F1P[e]  <=> F1P[c] ",null,null,"Transport, Extracellular"]
["R745","L-Fuculose 1-phosphate transport","FUCL1P[e]  <=> FUCL1P[c] ",null,null,"Transport, Extracellular"]
["R746","Ferrous ion transport via diffusion","Fe2[e]  <=> Fe2[c] ","(TTC0354 or TTC0776 or TTC1358)",null,"Transport, Extracellular"]
["R747","D-Fructose transport via ABC transporter","ATP[c] + H2O[c] + D_FRU[e]  -> ADP[c] + D_FRU[c] + H[c] + Pi[c] ","((TTC0326 or TTC0327) and TTC0328)",null,"Transport, Extracellular"]
["R748","Fumarate transport via proton symport","2 H[e] + FUM[e]  <=> 2 H[c] + FUM[c] ","TT_P0033 ",null,"Transport, Extracellular"]
["R749","alpha-D-Glucosamine 1-phosphate transport","GLUCSA1P[e]  <=> GLUCSA1P[c] ",null,null,"Transport, Extracellular"]
["R750","D-Glucosamine 6-phosphate transport","GLUSAP[e]  <=> GLUSAP[c] ",null,null,"Transport, Extracellular"]
["R751","Glycolaldehyde transport","GLYCALD[e]  <=> GLYCALD[c] ",null,null,"Transport, Extracellular"]
["R752","D-Glutamate transport","D_GLU[e]  <=> D_GLU[c] ",null,null,"Transport, Extracellular"]
["R753","Glycolate transport","HY_AC[e]  <=> HY_AC[c] ",null,null,"Transport, Extracellular"]
["R754","D-Glycerate transport","D_GLCT[e]  <=> D_GLCT[c] ",null,null,"Transport, Extracellular"]
["R755","Glycerol transport","GLYCRL[e]  <=> GLYCRL[c] ",null,null,"Transport, Extracellular"]
["R756","Glycine transport","L_GLY[e]  <=> L_GLY[c] ",null,null,"Transport, Extracellular"]
["R757","Hydrogen sulfide transport","H2S[e]  <=> H2S[c] ",null,null,"Transport, Extracellular"]
["R758","L-Homocysteine transport","L_HCYS[e]  <=> L_HCYS[c] ",null,null,"Transport, Extracellular"]
["R759","L-Isoleucine transport via ABC system","ATP[c] + H2O[c] + L_ILE[e]  -> L_ILE[c] + ADP[c] + Pi[c] ","((TTC0219 or TTC0334 or TTC0970 or TTC0600 or TTC0083) and (TTC0218 or TTC0335 or TTC0969 or TTC0078)) and ((TTC0220 or TTC0337 or TTC0598 or TTC0967 or TTC0080) and (TTC216 or TTC0968 or TTC0081))",null,"Transport, Extracellular"]
["R760","L-Lysine transport ","L_LYS[e]  <=> L_LYS[c]",null,null,"Transport, Extracellular"]
["R761","L-Malate transport via proton symport","2 H[e] + MAL[e]  <=> 2 H[c] + MAL[c] ","TT_P0033 ",null,"Transport, Extracellular"]
["R762","Maltose transport via ABC transporter","ATP[c] + H2O[c] + MALT[e]  -> ADP[c] + MALT[c] + H[c] + Pi[c] ","(((TTC1287 or TTC1286) and TTC1288) or ((TTC1628 or TTC1629) and TTC1627) or ((TTC0612 or TTC0613) and TTC0615))",null,"Transport, Extracellular"]
["R763","Isomaltose transport via ABC transporter","ATP[c] + H2O[c] + IMALT[e]  -> ADP[c] + IMALT[c] + H[c] + Pi[c] ",null,null,"Transport, Extracellular"]
["R764","D-Mannose 1-phosphate transport","MAN1P[e]  <=> MAN1P[c] ",null,null,"Transport, Extracellular"]
["R765","D-Mannose 6-phosphate transport","M6P[e]  <=> M6P[c] ",null,null,"Transport, Extracellular"]
["R766","D-Mannose transport via ABC transporter","ATP[c] + H2O[c] + D_MAN[e]  -> ADP[c] + D_MAN[c] + H[c] + Pi[c] ","((TTC0326 or TTC0327) and TTC0328)",null,"Transport, Extracellular"]
["R767","L-Phenylalanine transport","L_PHE[e]  <=> L_PHE[c]",null,null,"Transport, Extracellular"]
["R768","L-Proline transport","L_PRO[e]  <=> L_PRO[c]",null,null,"Transport, Extracellular"]
["R769","D-Ribose transport via proton symport","H[e] + D_RIB[e]  <=> H[c] + D_RIB[c] ","(TTC0734 and (TTC1505 or TTC1504) and TTC0733)",null,"Transport, Extracellular"]
["R770","D-Sorbitol transport","SORB[e]  <=> SORB[c] ",null,null,"Transport, Extracellular"]
["R771","L-Serine transport"," L_SER[e]  <=> L_SER[c]",null,null,"Transport, Extracellular"]
["R772","Sulfite transport","SO3[e]  <=> SO3[c] ",null,null,"Transport, Extracellular"]
["R773","Succinate transport via proton symport","2 H[e] + SUCC[e]  <=> 2 H[c] + SUCC[c] ","TT_P0033 ",null,"Transport, Extracellular"]
["R774","Sucrose transport via ABC transporter","ATP[c] + H2O[c] + SUC[e]  -> ADP[c] + SUC[c] + H[c] + Pi[c] ","(((TTC1287 or TTC1286) and TTC1288) or ((TTC1628 or TTC1629) and TTC1627) or ((TTC0612 or TTC0613) and TTC0615))",null,"Transport, Extracellular"]
["R775","L-Alanine transport via ABC system","ATP[c] + H2O[c] + L_ALA[e]  -> L_ALA[c] + ADP[c] + Pi[c] ","((TTC0219 or TTC0334 or TTC0970 or TTC0600 or TTC0083) and (TTC0218 or TTC0335 or TTC0969 or TTC0078)) and ((TTC0220 or TTC0337 or TTC0598 or TTC0967 or TTC0080) and (TTC216 or TTC0968 or TTC0081))",null,"Transport, Extracellular"]
["R776","L-Aspartate transport","L_ASP[e]  <=> L_ASP[c]",null,null,"Transport, Extracellular"]
["R777","L-Cysteine transport","L_CYS[e]  <=> L_CYS[c]",null,null,"Transport, Extracellular"]
["R778","L-Glutamate transport"," L_GLU[e]  <=> L_GLU[c]",null,null,"Transport, Extracellular"]
["R779","L-Methionine transport"," L_MET[e]  <=> L_MET[c]",null,null,"Transport, Extracellular"]
["R780","L-Threonine transport","L_THR[e]  <=> L_THR[c]",null,null,"Transport, Extracellular"]
["R781","L-Leucine transport via ABC system","ATP[c] + H2O[c] + L_LEU[e]  -> L_LEU[c] + ADP[c] + Pi[c] ","((TTC0219 or TTC0334 or TTC0970 or TTC0600 or TTC0083) and (TTC0218 or TTC0335 or TTC0969 or TTC0078)) and ((TTC0220 or TTC0337 or TTC0598 or TTC0967 or TTC0080) and (TTC216 or TTC0968 or TTC0081))",null,"Transport, Extracellular"]
["R782","L-Tryptophan transport","L_TRP[e]  <=> L_TRP[c]",null,null,"Transport, Extracellular"]
["R783","L-Tyrosine transport"," L_TYR[e]  <=> L_TYR[c]",null,null,"Transport, Extracellular"]
["R784","L-Valine transport via ABC system","ATP[c] + H2O[c] + L_VAL[e]  -> L_VAL[c] + ADP[c] + Pi[c] ","((TTC0219 or TTC0334 or TTC0970 or TTC0600 or TTC0083) and (TTC0218 or TTC0335 or TTC0969 or TTC0078)) and ((TTC0220 or TTC0337 or TTC0598 or TTC0967 or TTC0080) and (TTC216 or TTC0968 or TTC0081))",null,"Transport, Extracellular"]
["R785","Bicarbonate transport","HCO3[e]  <=> HCO3[c] ",null,null,"Transport, Extracellular"]
["R786","L-Lactate transport","LAC[e]  <=> LAC[c] ",null,null,"Transport, Extracellular"]
["R787","Ammonia transport","NH4[c]  <=> NH4[e] ",null,null,"Transport, Extracellular"]
["R788","Trehalose transport via ATP transporter","ATP[c] + H2O[c] + TRE[e]  -> ADP[c] + TRE[c] + H[c] + Pi[c] ","(((TTC1287 or TTC1286) and TTC1288) or ((TTC1628 or TTC1629) and TTC1627) or ((TTC0612 or TTC0613) and TTC0615))",null,"Transport, Extracellular"]
["R789","Magnesium transport via diffusion","Mg[e]  -> Mg[c] ","(TTC0695 or TTC1342)",null,"Transport, Extracellular"]
["R790","Heme export via diffusion","HEME[c]  -> HEME[e] ","(TTC1401 and TTC1402)",null,"Transport, Extracellular"]
["R791","D-Gluconate transport","GLCN[e]  -> GLCN[c] ",null,null,"Transport, Extracellular"]
["R792","Cellobiose transport via ABC system","ATP[c] + H2O[c] + CELBS[e]  -> ADP[c] + CELBS[c] + H[c] + Pi[c] ","(((TTC1287 or TTC1286) and TTC1288) or ((TTC1628 or TTC1629) and TTC1627) or ((TTC0612 or TTC0613) and TTC0615))",null,"Transport, Extracellular"]
["R793","Palatinose transport via ABC system","ATP[c] + H2O[c] + PALT[e]  -> ADP[c] + PALT[c] + H[c] + Pi[c] ","(((TTC1287 or TTC1286) and TTC1288) or ((TTC1628 or TTC1629) and TTC1627) or ((TTC0612 or TTC0613) and TTC0615))",null,"Transport, Extracellular"]
["R794","D-Galactose transport via ABC system","ATP[c] + H2O[c] + D_GAL[e]  -> ADP[c] + D_GAL[c] + H[c] + Pi[c] ","((TTC0326 or TTC0327) and TTC0328)",null,"Transport, Extracellular"]
["R795","Latose transport via ABC system","ATP[c] + H2O[c] + LACTS[e]  -> ADP[c] + LACTS[c] + H[c] + Pi[c] ","(((TTC1287 or TTC1286) and TTC1288) or ((TTC1628 or TTC1629) and TTC1627) or ((TTC0612 or TTC0613) and TTC0615))",null,"Transport, Extracellular"]
["R796","Stachyose transport via ABC system","ATP[c] + H2O[c] + STCYS[e]  -> ADP[c] + STCYS[c] + H[c] + Pi[c] ","(((TTC1287 or TTC1286) and TTC1288) or ((TTC1628 or TTC1629) and TTC1627) or ((TTC0612 or TTC0613) and TTC0615))",null,"Transport, Extracellular"]
["R797","PHB transport","PHB[c]  -> PHB[e] ",null,null,"Transport, Extracellular"]
["R798","PHV transport","PHV[c]  -> PHV[e] ",null,null,"Transport, Extracellular"]
["R799","PHO transport","PHO[c]  -> PHO[e] ",null,null,"Transport, Extracellular"]
["R800","PHD transport","PHD[c]  -> PHD[e] ",null,null,"Transport, Extracellular"]
["R801","PHDD transport","PHDD[c]  -> PHDD[e] ",null,null,"Transport, Extracellular"]
["R802","Glucose exchange","D_GLC[e]  <=> ",null,null,"Exchange Reactions"]
["R803","Water exchange","H2O[e]  <=> ",null,null,"Exchange Reactions"]
["R804","Oxygen exchange","O2[e]  <=> ",null,null,"Exchange Reactions"]
["R805","Sulfate exchange","SO4[e]  <=> ",null,null,"Exchange Reactions"]
["R806","Phosphate exchange","Pi[e]  <=> ",null,null,"Exchange Reactions"]
["R807","Carbon dioxide exchange","CO2[e]  <=> ",null,null,"Exchange Reactions"]
["R808","Acetate exchange","AC[e]  <=> ",null,null,"Exchange Reactions"]
["R809","D-Alanyl-D-alanine exchange","D_ALA_D_ALA[e]  <=> ",null,null,"Exchange Reactions"]
["R810","L-Arginine exchange","L_ARG[e]  <=> ",null,null,"Exchange Reactions"]
["R811","L-Asparagine exchange","L_ASN[e]  <=> ",null,null,"Exchange Reactions"]
["R812","Citrate exchange","CIT[e]  <=> ",null,null,"Exchange Reactions"]
["R813","Ethanol exchange","ETH[e]  <=> ",null,null,"Exchange Reactions"]
["R814","D-Fructose 1-phosphate exchange","F1P[e]  <=> ",null,null,"Exchange Reactions"]
["R815","L-Fuculose 1-phosphate exchange","FUCL1P[e]  <=> ",null,null,"Exchange Reactions"]
["R816","Ferrous ion exchange","Fe2[e]  <=> ",null,null,"Exchange Reactions"]
["R817","D-Fructose exchange","D_FRU[e]  <=> ",null,null,"Exchange Reactions"]
["R818","Fumarate exchange","FUM[e]  <=> ",null,null,"Exchange Reactions"]
["R819","alpha-D-Glucosamine 1-phosphate exchange","GLUCSA1P[e]  <=> ",null,null,"Exchange Reactions"]
["R820","D-Glucosamine 6-phosphate exchange","GLUSAP[e]  <=> ",null,null,"Exchange Reactions"]
["R821","Glycolaldehyde exchange","GLYCALD[e]  <=> ",null,null,"Exchange Reactions"]
["R822","D-Glutamate exchange","D_GLU[e]  <=> ",null,null,"Exchange Reactions"]
["R823","Glycolate exchange","HY_AC[e]  <=> ",null,null,"Exchange Reactions"]
["R824","D-Glycerate exchange","D_GLCT[e]  <=> ",null,null,"Exchange Reactions"]
["R825","Glycerol exchange","GLYCRL[e]  <=> ",null,null,"Exchange Reactions"]
["R826","Glycine exchange","L_GLY[e]  <=> ",null,null,"Exchange Reactions"]
["R827","Hydrogen sulfide exchange","H2S[e]  <=> ",null,null,"Exchange Reactions"]
["R828","L-Homocysteine exchange","L_HCYS[e]  <=> ",null,null,"Exchange Reactions"]
["R829","L-Isoleucine tansport","L_ILE[e]  <=> ",null,null,"Exchange Reactions"]
["R830","L-Lysine exchange","L_LYS[e]  <=> ",null,null,"Exchange Reactions"]
["R831","L-Malate exchange","MAL[e]  <=> ",null,null,"Exchange Reactions"]
["R832","Maltose exchange","MALT[e]  <=> ",null,null,"Exchange Reactions"]
["R833","Isomaltose exchange","IMALT[e]  <=> ",null,null,"Exchange Reactions"]
["R834","D-Mannose 1-phosphate exchange","MAN1P[e]  <=> ",null,null,"Exchange Reactions"]
["R835","D-Mannose 6-phosphate exchange","M6P[e]  <=> ",null,null,"Exchange Reactions"]
["R836","D-Mannose exchange","D_MAN[e]  <=> ",null,null,"Exchange Reactions"]
["R837","L-Phenylalanine exchange","L_PHE[e]  <=> ",null,null,"Exchange Reactions"]
["R838","L-Proline exchange","L_PRO[e]  <=> ",null,null,"Exchange Reactions"]
["R839","D-Ribose exchange","D_RIB[e]  <=> ",null,null,"Exchange Reactions"]
["R840","D-Sorbitol exchange","SORB[e]  <=> ",null,null,"Exchange Reactions"]
["R841","L-Serine exchange","L_SER[e]  <=> ",null,null,"Exchange Reactions"]
["R842","Sulfite exchange","SO3[e]  <=> ",null,null,"Exchange Reactions"]
["R843","Succinate exchange","SUCC[e]  <=> ",null,null,"Exchange Reactions"]
["R844","Sucrose exchange","SUC[e]  <=> ",null,null,"Exchange Reactions"]
["R845","L-Alanine exchange","L_ALA[e]  <=> ",null,null,"Exchange Reactions"]
["R846","L-Aspartate exchange","L_ASP[e]  <=> ",null,null,"Exchange Reactions"]
["R847","L-Cysteine exchange","L_CYS[e]  <=> ",null,null,"Exchange Reactions"]
["R848","L-Glutamate exchange","L_GLU[e]  <=> ",null,null,"Exchange Reactions"]
["R849","L-Methionine exchange","L_MET[e]  <=> ",null,null,"Exchange Reactions"]
["R850","L-Threonine exchange","L_THR[e]  <=> ",null,null,"Exchange Reactions"]
["R851","L-Leucine exchange","L_LEU[e]  <=> ",null,null,"Exchange Reactions"]
["R852","L-Tryptophan exchange","L_TRP[e]  <=> ",null,null,"Exchange Reactions"]
["R853","L-Tyrosine exchange","L_TYR[e]  <=> ",null,null,"Exchange Reactions"]
["R854","L-Valine exchange","L_VAL[e]  <=> ",null,null,"Exchange Reactions"]
["R855","Bicarbonate exchange","HCO3[e]  <=> ",null,null,"Exchange Reactions"]
["R856","L-Lactate exchange","LAC[e]  <=> ",null,null,"Exchange Reactions"]
["R857","Ammonia exchange","NH4[e]  <=> ",null,null,"Exchange Reactions"]
["R858","Trehalose exchange","TRE[e]  <=> ",null,null,"Exchange Reactions"]
["R859","Magnesium exchange","Mg[e]  <=> ",null,null,"Exchange Reactions"]
["R860","HEME exchange","HEME[e]  <=> ",null,null,"Exchange Reactions"]
["R861","Gluconate exchange","GLCN[e]  <=> ",null,null,"Exchange Reactions"]
["R862","Cellobiose exchange","CELBS[e]  <=> ",null,null,"Exchange Reactions"]
["R863","Palatinose exchange","PALT[e]  <=> ",null,null,"Exchange Reactions"]
["R864","D-Galactose exchange","D_GAL[e]  <=> ",null,null,"Exchange Reactions"]
["R865","PHB exchange","PHB[e]  <=> ",null,null,"Exchange Reactions"]
["R866","PHV exchange","PHV[e]  <=> ",null,null,"Exchange Reactions"]
["R867","PHO exchange","PHO[e]  <=> ",null,null,"Exchange Reactions"]
["R868","PHD exchange","PHD[e]  <=> ",null,null,"Exchange Reactions"]
["R869","PHDD exchange","PHDD[e]  <=> ",null,null,"Exchange Reactions"]
["R870","H exchange","H[e] <=>",null,null,"Exchange Reactions"]
["R871","Lactose exchange","LACTS[e]  <=> ",null,null,"Exchange Reactions"]
["R872","Stachyose exchange","STCYS[e]  <=> ",null,null,"Exchange Reactions"]

{"sheet":"A2","index":2,"n_rows":709,"n_cols":6,"rows_kept":709,"flags":["formulas_cached_only"]}
["Abbreviation","Name","Formula (neutral)","Formula (charged)","Charge","Compartment"]
["10F_THF[c]","10-Formyltetrahydrofolate","C20H23N7O7","C20H23N7O7",0,"Cytosol"]
["13BPG[c]","1,3-Bisphospho-D-glycerate","C3H8O10P2","C3H8O10P2",0,"Cytosol"]
["2HY_5CARBMMUC_SA[c]","2-Hydroxy-5-carboxymethylmuconate semialdehyde","C8H8O6","C8H8O6",0,"Cytosol"]
["2HYBUTNA[c]","2-Hydroxybutyrate","C4H8O3","C4H8O3",0,"Cytosol"]
["2K3DO_GLCN[c]","2-Dehydro-3-deoxy-D-gluconate","C6H10O6","C6H10O6",0,"Cytosol"]
["2K3M_BUT[c]","3-Methyl-2-oxobutanoate","C5H8O3","C5H8O3",0,"Cytosol"]
["2M_PROCoA[c]","2-Methylpropanoyl-CoA","C25H42N7O17P3S","C25H42N7O17P3S",0,"Cytosol"]
["2M4A_HYMPYRMPPi[c]","2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate","C6H11N3O7P2","C6H11N3O7P2",0,"Cytosol"]
["2MHYBUT_ThPP[c]","2-Methyl-1-hydroxybutyl-ThPP","C17H29N4O8P2S","C17H29N4O8P2S",0,"Cytosol"]
["2MHYPROP_ThPP[c]","2-Methyl-1-hydroxypropyl-ThPP","C16H27N4O8P2S","C16H27N4O8P2S",0,"Cytosol"]
["2OADPA[c]","2-Oxoadipate","C6H8O5","C6H8O5",0,"Cytosol"]
["2P_GLYCA[c]","2-Phosphoglycolate","C2H5O6P","C2H5O6P",0,"Cytosol"]
["2PG[c]","D-Glycerate 2-phosphate","C3H7O7P","C3H7O7P",0,"Cytosol"]
["3AIBUTNA[c]","3-Aminoisobutanoate","C4H9NO2","C4H9NO2",0,"Cytosol"]
["3DHYQNT[c]","3-Dehydroquinate","C7H10O6","C7H10O6",0,"Cytosol"]
["3HY_2M_2OBUTNA[c]","3-Hydroxy-3-methyl-2-oxobutanoic acid","C5H8O4","C5H8O4",0,"Cytosol"]
["3M_2OPENTN[c]","(S)-3-Methyl-2-oxopentanoate","C6H10O3","C6H10O3",0,"Cytosol"]
["3MGLUTNCoA[c]","3-Methylglutaconyl-CoA ","C27H42N7O19P3S","C27H42N7O19P3S",0,"Cytosol"]
["3MHYBUT_ThPP[c]","3-Methyl-1-hydroxybutyl-ThPP","C17H29N4O8P2S","C17H29N4O8P2S",0,"Cytosol"]
["3PG[c]","D-Glycerate 3-phosphate","C3H7O7P","C3H7O7P",0,"Cytosol"]
["3POXPYR[c]","3-Phosphonooxypyruvate","C3H5O7P","C3H5O7P",0,"Cytosol"]
["4A_M5PM_PYRM[c]","4-Amino-2-methyl-5-phosphomethylpyrimidine, 4-Amino-5-phosphomethyl-2-methylpyrimidine","C6H10N3O4P","C6H10N3O4P",0,"Cytosol"]
["4A4CORM[c]","(2S)-2-Amino-4-deoxychorismate","C10H11NO5","C10H11NO5",0,"Cytosol"]
["4ABUT[c]","4-Aminobutanoate","C4H9NO2","C4H9NO2",0,"Cytosol"]
["4ABUTALD[c]","4-Aminobutyraldehyde","C4H9NO","C4H9NO",0,"Cytosol"]
["4HY_2OGLUTR[c]","4-Hydroxy-2-oxoglutarate","C5H6O6","C5H6O6",0,"Cytosol"]
["4M_2OPENTN[c]","4-Methyl-2-oxopentanoate","C6H10O3","C6H10O3",0,"Cytosol"]
["4M_PE_THZ[c]","4-Methyl-5-(2-phosphoethyl)-thiazole","C6H10NO4PS","C6H10NO4PS",0,"Cytosol"]
["4P_ASP[c]","4-Phospho-L-aspartate","C4H8NO7P","C4H8NO7P",0,"Cytosol"]
["5_10_MNTHF[c]","5,10-Methylenetetrahydrofolate","C20H23N7O6","C20H23N7O6",0,"Cytosol"]
["5A_4IMDZCARBA[c]","5-Amino-4-imidazolecarboxyamide","C4H6N4O","C4H6N4O",0,"Cytosol"]
["5AM_RIBAM_URA[c]","5-Amino-6-(1-D-ribitylamino)uracil","C9H16N4O6","C9H16N4O6",0,"Cytosol"]
["5CAIZ[c]","5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole","C9H14N3O9P","C9H14N3O9P",0,"Cytosol"]
["5MTHF[c]","5-Methyltetrahydrofolate","C20H25N7O6","C20H25N7O6",0,"Cytosol"]
["5PRIBS_ANTRL[c]","N-(5-Phospho-D-ribosyl)anthranilate","C12H16NO9P","C12H16NO9P",0,"Cytosol"]
["A_OXBUT[c]","L-2-Amino-3-oxobutanoate","C4H7NO3","C4H7NO3",0,"Cytosol"]
["A_PROPOL[c]","(R)-1-Amino-2-propanol","C3H9NO","C3H9NO",0,"Cytosol"]
["AAC[c]","Acetoacetate","C4H6O3","C4H6O3",0,"Cytosol"]
["AADP[c]","L-2-Aminoadipate",null,null,0,"Cytosol"]
["AALD[c]","Acetaldehyde","C2H4O","C2H4O",0,"Cytosol"]
["ABEE[c]","p-Aminobenzoate","C7H7NO2","C7H7NO2",0,"Cytosol"]
["AC[c]","Acetate","C2H4O2","C2H4O2",0,"Cytosol"]
["AC[e]","Acetate","C2H4O2","C2H4O2",0,"Extra-organism"]
["AC_AADP[c]","N2-Acetyl-L-aminoadipate","C8H13NO5","C8H13NO5",0,"Cytosol"]
["AC_AADP_DELPi[c]","N2-Acetyl-L-aminoadipyl-delta-phosphate","C8H14NO8P","C8H14NO8P",0,"Cytosol"]
["AC_AADP_SA[c]","N2-Acetyl-L-aminoadipate semialdehyde","C8H13NO4","C8H13NO4",0,"Cytosol"]
["AC_AGLUCSAPi[c]","N-Acetyl-alpha-D-glucosamine 1-phosphate","C8H16NO9P","C8H16NO9P",0,"Cytosol"]
["AC_GLUSAP[c]","N-Acetyl-D-glucosamine 6-phosphate","C8H16NO9P","C8H16NO9P",0,"Cytosol"]
["AC_GLUT[c]","N-Acetyl-L-glutamate","C7H11NO5","C7H11NO5",0,"Cytosol"]
["AC_GLUT_SA[c]","N-Acetyl-L-glutamate 5-semialdehyde","C7H11NO4","C7H11NO4",0,"Cytosol"]
["AC_GLUTPi[c]","N-Acetyl-L-glutamate 5-phosphate","C7H12NO8P","C7H12NO8P",0,"Cytosol"]
["AC_HYBUTNA[c]","(S)-2-Aceto-2-hydroxybutanoate","C6H10O4","C6H10O4",0,"Cytosol"]
["ACACoA[c]","Acetoacetyl-CoA","C25H40N7O18P3S","C25H40N7O18P3S",0,"Cytosol"]
["ACADNA[c]","Acetyl adenylate","C12H16N5O8P","C12H16N5O8P",0,"Cytosol"]
["ACoA[c]","Acetyl-CoA","C23H38N7O17P3S","C23H38N7O17P3S",0,"Cytosol"]
["ACP[c]","Acyl-carrier protein (ACP)","HSR","HSR",0,"Cytosol"]
["ACPi[c]","Acetyl phosphate","C2H5O5P","C2H5O5P",0,"Cytosol"]
["ADHY_DPOM_PTRDN[c]","2-Amino-7,8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine","C7H11N5O8P2","C7H11N5O8P2",0,"Cytosol"]
["ADN[c]","Adenine","C5H5N5","C5H5N5",0,"Cytosol"]
["ADN_SUCC[c]","Adenylosuccinate","C14H18N5O11P","C14H18N5O11P",0,"Cytosol"]
["ADNS_CABYRDA[c]","Adenosyl cobyrinate diamide","C55H73CoN11O15","C55H73CoN11O15",0,"Cytosol"]
["ADNS_CABYRHA[c]","Adenosyl cobyrinate hexaamide","C55H77CoN15O11","C55H77CoN15O11",0,"Cytosol"]
["ADNS_CBNA[c]","Adenosyl cobinamide","C58H84CoN16O11","C58H84CoN16O11",0,"Cytosol"]
["ADNS_CBNA_GDP[c]","Adenosine-GDP-cobinamide","C68H97CoN21O21P2","C68H97CoN21O21P2",0,"Cytosol"]
["ADNS_CBNAPi[c]","Adenosyl cobinamide phosphate","C58H85CoN16O14P","C58H85CoN16O14P",0,"Cytosol"]
["ADP[c]","Adenosine 5'-diphosphate (ADP)","C10H15N5O10P2","C10H15N5O10P2",0,"Cytosol"]
["ADP_GLU[c]","ADP-glucose","C16H25N5O15P2","C16H25N5O15P2",0,"Cytosol"]
["ADP_RIB[c]","ADP-D-ribose","C15H23N5O14P2","C15H23N5O14P2",0,"Cytosol"]
["ADSN[c]","Adenosine","C10H13N5O4","C10H13N5O4",0,"Cytosol"]
["AGAL_INS[c]","Galactinol","C12H22O11","C12H22O11",0,"Cytosol"]
["AGMT[c]","Agmatine","C5H14N4","C5H14N4",0,"Cytosol"]
["AHY_HYM_DHYPTR[c]","2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine","C7H9N5O2","C7H9N5O2",0,"Cytosol"]
["AHYRY_THYPROP_DHYPTRN_TPi[c]","2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate","C9H16N5O13P3","C9H16N5O13P3",0,"Cytosol"]
["AI150[c]","12-Methyl-tetradecanoate (anteiso-15:0)",null,null,0,"Cytosol"]
["AI150CoA[c]","Anteiso-C15:0 CoA","C36H60N7O17P3S1","C36H60N7O17P3S1",0,"Cytosol"]
["AI171[c]","14-Methyl-hexadecenoate (anteiso-17:1)",null,null,0,"Cytosol"]
["AI171CoA[c]","Anteiso-C17:1 CoA","C38H62N7O17P3S1","C38H62N7O17P3S1",0,"Cytosol"]
["AICAR[c]","1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide","C9H15N4O8P","C9H15N4O8P",0,"Cytosol"]
["AIR[c]","Aminoimidazole ribotide (AIR)","C8H14N3O7P","C8H14N3O7P",0,"Cytosol"]
["AKB[c]","alpha-Ketobutyric acid","C4H6O3","C4H6O3",0,"Cytosol"]
["AKG[c]","alpha-Ketoglutaric acid","C5H6O5","C5H6O5",0,"Cytosol"]
["ALEVU[c]","5-Aminolevulinate","C5H9NO3","C5H9NO3",0,"Cytosol"]
["AMANN_GLYCT[c]","2(alpha-D-Mannosyl)-D-glycerate","C9H16O9","C9H16O9",0,"Cytosol"]
["AMDHY_LPP[c]","S-Aminomethyldihydrolipoylprotein","C9H19N2OS2R","C9H19N2OS2R",0,"Cytosol"]
["AMP[c]","Adenosine 5'-monophosphate (AMP)","C10H14N5O7P","C10H14N5O7P",0,"Cytosol"]
["ANTHRL[c]","Anthranilate","C7H7NO2","C7H7NO2",0,"Cytosol"]
["AORT[c]","N-Acetylornithine","C7H14N2O3","C7H14N2O3",0,"Cytosol"]
["AP_RIB_URA[c]","5-Amino-6-(5'-phosphoribosylamino)uracil","C9H15N4O9P","C9H15N4O9P",0,"Cytosol"]
["APCARB[c]","Apo-[carboxylase]","C7H13N3O2R2","C7H13N3O2R2",0,"Cytosol"]
["APPRO[c]","Apoprotein","NH2R","NH2R",0,"Cytosol"]
["APRIBTA_URA[c]","5-Amino-6-(5'-phospho-D-ribitylamino)uracil","C9H17N4O9P","C9H17N4O9P",0,"Cytosol"]
["APRNPi[c]","D-1-Aminopropan-2-ol O-phosphate","C3H10NO4P","C3H10NO4P",0,"Cytosol"]
["APS[c]","Adenylyl sulfate","C10H14N5O10PS","C10H14N5O10PS",0,"Cytosol"]
["ARIBZ[c]","alpha-Ribazole","C14H18N2O4","C14H18N2O4",0,"Cytosol"]
["ASP_4SA[c]","L-Aspartate 4-semialdehyde","C4H7NO3","C4H7NO3",0,"Cytosol"]
["ATP[c]","Adenosine 5'-triphosphate (ATP)","C10H16N5O13P3","C10H16N5O13P3",0,"Cytosol"]
["B_ALA[c]","beta-Alanine","C3H7NO2","C3H7NO2",0,"Cytosol"]
["BADNS_PPP[c]","P1,P4-Bis(5'-adenosyl) tetraphosphate (AppppA)","C20H28N10O19P4","C20H28N10O19P4",0,"Cytosol"]
["bCARO[c]","beta-Carotene","C40H56","C40H56",0,"Cytosol"]
["bCRTX_GLU[c]","beta-Cryptoxanthin glucoside",null,null,0,"Cytosol"]
["BGUNS_PPP[c]","P1,P4-Bis(5'-guanosyl) tetraphosphate (GppppG)","C20H28N10O21P4","C20H28N10O21P4",0,"Cytosol"]
["BTN[c]","Biotin","C10H16N2O3S","C10H16N2O3S",0,"Cytosol"]
["BTN_AMP[c]","Biotinyl-5'-AMP","C20H28N7O9PS","C20H28N7O9PS",0,"Cytosol"]
["C160[c]","Hexadecanoate","C16H32O2","C16H32O2",0,"Cytosol"]
["C160CoA[c]","Palmitoyl-CoA (n-C16:0CoA)","C37H66N7O17P3S","C37H66N7O17P3S",0,"Cytosol"]
["C161[c]","Palmitoleate","C16H30O2","C16H30O2",0,"Cytosol"]
["C161CoA[c]","(2E)-Hexadecenoyl-CoA (n-C16:1CoA)","C37H64N7O17P3S","C37H64N7O17P3S",0,"Cytosol"]
["CABYRDA[c]","Cob(I)yrinate diamide","C45H61CoN6O12","C45H61CoN6O12",0,"Cytosol"]
["cACO[c]","cis-Aconitate","C6H6O6","C6H6O6",0,"Cytosol"]
["CAIR[c]","1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate","C9H14N3O9P","C9H14N3O9P",0,"Cytosol"]
["CARB_ASP[c]","N-Carbamoyl-L-aspartate","C5H8N2O5","C5H8N2O5",0,"Cytosol"]
["CARB_Pi[c]","Carbamoyl phosphate","CH4NO5P","CH4NO5P",0,"Cytosol"]
["CARBM_HYMUC[c]","5-Carboxymethyl-2-hydroxymuconate","C8H8O7","C8H8O7",0,"Cytosol"]
["CBAMD[c]","Cobinamide","C48H72CoN11O8","C48H72CoN11O8",0,"Cytosol"]
["CBMCo[c]","Cobamide coenzyme","C72H100CoN18O17P","C72H100CoN18O17P",0,"Cytosol"]
["CBRYNA[c]","Cobyrinate","C45H59CoN4O14","C45H59CoN4O14",0,"Cytosol"]
["CBTN_CCP[c]","Carboxybiotin-carboxyl-carrier protein","C18H26N5O6SR2","C18H26N5O6SR2",0,"Cytosol"]
["CDLPN[c]","cardiolipin",null,null,0,"Cytosol"]
["CDP[c]","Cytidine 5'-diphosphate (CDP)","C9H15N3O11P2","C9H15N3O11P2",0,"Cytosol"]
["CDP_DAG[c]","CDP-1,2-diacylglycerol","C14H19N3O15P2R2","C14H19N3O15P2R2",0,"Cytosol"]
["CELBS[c]","Cellobiose","C12H22O11","C12H22O11",0,"Cytosol"]
["CELBS[e]","Cellobiose","C12H22O11","C12H22O11",0,"Extra-organism"]
["CIT[c]","Citrate","C6H8O7","C6H8O7",0,"Cytosol"]
["CIT[e]","Citrate","C6H8O7","C6H8O7",0,"Extra-organism"]
["CMP[c]","Cytidine-5'-monophosphate (CMP)","C9H14N3O8P","C9H14N3O8P",0,"Cytosol"]
["CO(II)[c]","Cobalt",null,null,0,"Cytosol"]
["CO2[c]","Carbon dioxide","CO2","CO2",0,"Cytosol"]
["CO2[e]","Carbon dioxide","CO2","CO2",0,"Extra-organism"]
["Co2ABYRDA[c]","Cob(II)yrinate diamide","C45H61CoN6O12","C45H61CoN6O12",0,"Cytosol"]
["CoA[c]","Coenzyme A (CoA)","C21H36N7O16P3S","C21H36N7O16P3S",0,"Cytosol"]
["CoFIII[c]","Cobalt-factor III","C43H46CoN4O16","C43H46CoN4O16",0,"Cytosol"]
["CoPRCRN3[c]","Cobalt-precorrin 3","C43H48CoN4O16","C43H48CoN4O16",0,"Cytosol"]
["CoPRCRN4[c]","Cobalt-precorrin 4","C44H50CoN4O16","C44H50CoN4O16",0,"Cytosol"]
["CoPRCRN5A[c]","Cobalt-precorrin 5A","C45H52CoN4O16","C45H52CoN4O16",0,"Cytosol"]
["CoPRCRN8[c]","Cobalt-precorrin 8","C45H59CoN4O14","C45H59CoN4O14",0,"Cytosol"]
["CORM[c]","Chorismate","C10H10O6","C10H10O6",0,"Cytosol"]
["CoSRHYCLR[c]","Cobalt-sirohydrochlorin","C42H44CoN4O16","C42H44CoN4O16",0,"Cytosol"]
["CPhA_dRBL5P[c]","1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate","C12H16NO9P","C12H16NO9P",0,"Cytosol"]
["CPPHYRGN_I[c]","Coproporphyrinogen I","C36H44N4O8","C36H44N4O8",0,"Cytosol"]
["CPPPHYRGN[c]","Coproporphyrinogen III","C36H44N4O8","C36H44N4O8",0,"Cytosol"]
["CRBX_OHEPTEDA[c]","5-Carboxy-2-oxohept-3-enedioate","C8H8O7","C8H8O7",0,"Cytosol"]
["CROCoA[c]","Crotonoyl-CoA","C25H40N7O17P3S","C25H40N7O17P3S",0,"Cytosol"]
["CRTX[c]","beta-Cryptoxanthin","C40H56O","C40H56O",0,"Cytosol"]
["CRVN[c]","(+)-(S)-Carvone","C10H14O","C10H14O",0,"Cytosol"]
["ct_FARPPi[c]","2-cis,6-trans-Farnesyl diphosphate","C15H28O7P2","C15H28O7P2",0,"Cytosol"]
["CTP[c]","Cytidine 5'-triphosphate (CTP)","C9H16N3O14P3","C9H16N3O14P3",0,"Cytosol"]
["CTRLN[c]","L-Citrulline","C6H13N3O3","C6H13N3O3",0,"Cytosol"]
["CVP_SHK[c]","5-O-(1-Carboxyvinyl)-3-phosphoshikimate","C10H13O10P","C10H13O10P",0,"Cytosol"]
["CYSTHN[c]","Cystathionine","C7H14N2O4S","C7H14N2O4S",0,"Cytosol"]
["CYT_C2[c]","Ferrocytochrome c","C42H44FeN8O8S2R4","C42H44FeN8O8S2R4",0,"Cytosol"]
["CYT_C3[c]","Ferricytochrome c","C42H44FeN8O8S2R4","C42H44FeN8O8S2R4",0,"Cytosol"]
["CYTD[c]","Cytidine","C9H13N3O5","C9H13N3O5",0,"Cytosol"]
["CYTPPi_MEROL[c]","4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol","C14H25N3O14P2","C14H25N3O14P2",0,"Cytosol"]
["D_ALA[c]","D-Alanine","C3H7NO2","C3H7NO2",0,"Cytosol"]
["D_ALA_D_ALA[c]","D-Alanyl-D-alanine","C6H12N2O3","C6H12N2O3",0,"Cytosol"]
["D_ALA_D_ALA[e]","D-Alanyl-D-alanine","C6H12N2O3","C6H12N2O3",0,"Extra-organism"]
["D_FRU[c]","D-Fructose","C6H12O6","C6H12O6",0,"Cytosol"]
["D_FRU[e]","D-Fructose","C6H12O6","C6H12O6",0,"Extra-organism"]
["D_GAL[c]","D-Galactose","C6H12O6","C6H12O6",0,"Cytosol"]
["D_GAL[e]","D-Galactose","C6H12O6","C6H12O6",0,"Extra-organism"]
["D_GLC[c]","D-Glucose","C6H12O6","C6H12O6",0,"Cytosol"]
["D_GLC[e]","D-Glucose","C6H12O6","C6H12O6",0,"Cytosol"]
["D_GLCT[c]","D-Glycerate","C3H6O4","C3H6O4",0,"Cytosol"]
["D_GLCT[e]","D-Glycerate","C3H6O4","C3H6O4",0,"Extra-organism"]
["D_GLU[c]","D-Glutamate","C5H9NO4","C5H9NO4",0,"Cytosol"]
["D_GLU[e]","D-Glutamate","C5H9NO4","C5H9NO4",0,"Extra-organism"]
["D_MAN[c]","D-Mannose","C6H12O6","C6H12O6",0,"Cytosol"]
["D_MAN[e]","D-Mannose","C6H12O6","C6H12O6",0,"Extra-organism"]
["D_RIB[c]","D-Ribose","C5H10O5","C5H10O5",0,"Cytosol"]
["D_RIB[e]","D-Ribose","C5H10O5","C5H10O5",0,"Extra-organism"]
["DA_NAD[c]","Deamino-NAD+","C21H27N6O15P2","C21H27N6O15P2",0,"Cytosol"]
["DA_PRIBSA_PYMDN[c]","2,5-Diamino-6-(5'-phosphoribosylamino)-4-pyrimidineone","C9H16N5O8P","C9H16N5O8P",0,"Cytosol"]
["DA_TPiTHY_OPENTAOPYRM[c]","2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)- amino-4-oxopyrimidine","C9H18N5O14P3","C9H18N5O14P3",0,"Cytosol"]
["dADNS[c]","5'-Deoxyadenosine","C10H13N5O3","C10H13N5O3",0,"Cytosol"]
["dADP[c]","2'-Deoxyadenosine 5'-diphosphate (dADP)","C10H15N5O9P2","C10H15N5O9P2",0,"Cytosol"]
["dADS[c]","Deoxyadenosine","C10H13N5O3","C10H13N5O3",0,"Cytosol"]
["DAG[c]","1,2-Diacyl-sn-glycerol","C5H6O5R2","C5H6O5R2",0,"Cytosol"]
["dAMP[c]","Deoxyadenosine monophosphate (dAMP)","C10H14N5O6P","C10H14N5O6P",0,"Cytosol"]
["DAPYRM_NTP[c]","2,5-Diaminopyrimidine nucleoside triphosphate","C9H18N5O14P3","C9H18N5O14P3",0,"Cytosol"]
["dATP[c]","Deoxyadenosine 5'-triphosphate (dATP)","C10H16N5O12P3","C10H16N5O12P3",0,"Cytosol"]
["dCDP[c]","2'-Deoxycytidine diphosphate (dCDP)","C9H15N3O10P2","C9H15N3O10P2",0,"Cytosol"]
["dCMP[c]","Deoxycytidine monophosphate","C9H14N3O7P","C9H14N3O7P",0,"Cytosol"]
["dCTP[c]","Deoxycytidine 5'-triphosphate (dCTP)","C9H16N3O13P3","C9H16N3O13P3",0,"Cytosol"]
["dCYTD[c]","2'-Deoxycytidine","C9H13N3O4","C9H13N3O4",0,"Cytosol"]
["DEMQH2[c]","3-Demethylubiquinol",null,null,0,"Cytosol"]
["DGALSCRAMD[c]","Digalactosylceramide","C31H56NO13R","C31H56NO13R",0,"Cytosol"]
["DGDG[c]","diglucosyl-1,2 diacylglycerol",null,null,0,"Cytosol"]
["dGDP[c]","2'-Deoxyguanosine 5'-diphosphate (dGDP)","C10H15N5O10P2","C10H15N5O10P2",0,"Cytosol"]
["dGMP[c]","Deoxyguanosine monophosphate","C10H14N5O7P","C10H14N5O7P",0,"Cytosol"]
["dGTP[c]","2'-Deoxyguanosine 5'-triphosphate (dGTP)","C10H16N5O13P3","C10H16N5O13P3",0,"Cytosol"]
["dGUNS[c]","Deoxyguanosine","C10H13N5O4","C10H13N5O4",0,"Cytosol"]
["DHADPCoA[c]","2,3-dehydroadipyl-CoA","C27H37N7O19P3S","C27H37N7O19P3S",0,"Cytosol"]
["DHAP[c]","Dihydroxyacetone phosphate","C3H7O6P","C3H7O6P",0,"Cytosol"]
["DHF[c]","Dihydrofolate","C19H21N7O6","C19H21N7O6",0,"Cytosol"]
["DHLPL_SUCCT_GLUTRDHLPL[c]","[Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine, S-Glutaryldihydrolipoamide-E","C13H22NO4S2R","C13H22NO4S2R",0,"Cytosol"]
["dhPhAC[c]",{"$nulls":3},0,"Cytosol"]
["dhPhACoA[c]","2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA","C29H38N7O18P3S","C29H38N7O18P3S",0,"Cytosol"]
["DHTHYM[c]","5,6-dihydrothymine","C5H8N2O2","C5H8N2O2",0,"Cytosol"]
["DHY_BUTNPi[c]","3,4-Dihydroxy-2-butanone 4-phosphate","C4H9O6P","C4H9O6P",0,"Cytosol"]
["DHY_DOHEXNA[c]","(4S)-4,6-Dihydroxy-2,5-dioxohexanoate","C6H8O6","C6H8O6",0,"Cytosol"]
["DHY_DOP_GLUCN[c]","2-Dehydro-3-deoxy-6-phospho-D-gluconate","C6H11O9P","C6H11O9P",0,"Cytosol"]
["DHY_DPICLN[c]","Dihydrodipicolinate","C7H7NO4","C7H7NO4",0,"Cytosol"]
["DHY_LPP[c]","Dihydrolipoylprotein","C8H16NOS2R","C8H16NOS2R",0,"Cytosol"]
["DHY_MBUTNA[c]","2,3-Dihydroxy-3-methylbutanoate","C5H10O4","C5H10O4",0,"Cytosol"]
["DHY_MPENTA[c]","(R)-2,3-Dihydroxy-3-methylpentanoate","C6H12O4","C6H12O4",0,"Cytosol"]
["DHY_NPTRN[c]","Dihydroneopterin, 7,8-Dihydroneopterin","C9H13N5O4","C9H13N5O4",0,"Cytosol"]
["DHY_ORTA[c]","(S)-Dihydroorotate","C5H6N2O4","C5H6N2O4",0,"Cytosol"]
["DHY_PAN[c]","2-Dehydropantoate","C6H10O4","C6H10O4",0,"Cytosol"]
["DHY_PENTDON[c]","(4S)-4,5-Dihydroxypentan-2,3-dione","C5H8O4","C5H8O4",0,"Cytosol"]
["dHY_PhAC[c]","3,4-Dihydroxyphenylacetate","C8H8O4","C8H8O4",0,"Cytosol"]
["DHY_PTR[c]","Dihydropteroate","C14H14N6O3","C14H14N6O3",0,"Cytosol"]
["DHY_SHK[c]","3-Dehydroshikimate","C7H8O5","C7H8O5",0,"Cytosol"]
["DHYDO_ARAB_HEPTP[c]","2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate","C7H13O10P","C7H13O10P",0,"Cytosol"]
["DHYGLCN[c]","5-Dehydro-D-gluconate","C6H10O7","C6H10O7",0,"Cytosol"]
["DHYLPL_MPROP_2MBUT_DHLPL[c]","[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine","C13H24NO2S2R","C13H24NO2S2R",0,"Cytosol"]
["DHYLPL_MPROP_3MBUT_DHLPL[c]","[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine","C13H24NO2S2R","C13H24NO2S2R",0,"Cytosol"]
["DHYLPL_MPROP_MPROP_DHLPL[c]","[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine","C12H22NO2S2R","C12H22NO2S2R",0,"Cytosol"]
["dIDP[c]","2'-Deoxyinosine-5'-diphosphate (dIDP)","C10H14N4O10P2","C10H14N4O10P2",0,"Cytosol"]
["dIMP[c]","2'-Deoxyinosine 5'-phosphate (dIMP)","C10H13N4O7P","C10H13N4O7P",0,"Cytosol"]
["dITP[c]","2'-Deoxyinosine-5'-triphosphate (dITP)","C10H15N4O13P3","C10H15N4O13P3",0,"Cytosol"]
["DM_DR_LUM[c]","6,7-Dimethyl-8-(1-D-ribityl)lumazine","C13H18N4O6","C13H18N4O6",0,"Cytosol"]
["DMAPP[c]","Dimethylallyl diphosphate","C5H12O7P2","C5H12O7P2",0,"Cytosol"]
["DMMQ[c]","2-Demethylmenaquinone","C15H14O2(C5H8)n","C15H14O2(C5H8)n",0,"Cytosol"]
["DPCoA[c]","Dephospho-CoA","C21H35N7O13P2S","C21H35N7O13P2S",0,"Cytosol"]
["dR1P[c]","2-Deoxy-D-ribose 1-phosphate","C5H11O7P","C5H11O7P",0,"Cytosol"]
["dR5P[c]","2-Deoxy-D-ribose 5-phosphate","C5H11O7P","C5H11O7P",0,"Cytosol"]
["dt_pc_UNDECP[c]","Undecaprenyl phosphate","C55H91O4P","C55H91O4P",0,"Cytosol"]
["dt_pc_UNDECPPi[c]","di-trans,poly-cis-Undecaprenyl diphosphate","C55H92O7P2","C55H92O7P2",0,"Cytosol"]
["DTBTN[c]","Dethiobiotin","C10H18N2O3","C10H18N2O3",0,"Cytosol"]
["dTDP[c]","Deoxythymidine 5'-diphosphate (dTDP)","C10H16N2O11P2","C10H16N2O11P2",0,"Cytosol"]
["dTMP[c]","Thymidine 5'-phosphat (Dtmp)","C10H15N2O8P","C10H15N2O8P",0,"Cytosol"]
["dTTP[c]","Deoxythymidine triphosphate","C10H17N2O14P3","C10H17N2O14P3",0,"Cytosol"]
["dUDP[c]","2'-Deoxyuridine 5'-diphosphate (dUDP)","C9H14N2O11P2","C9H14N2O11P2",0,"Cytosol"]
["dUMP[c]","Deoxyuridine 5'-phosphate (dUMP)","C9H13N2O8P","C9H13N2O8P",0,"Cytosol"]
["dURD[c]","Deoxyuridine","C9H12N2O5","C9H12N2O5",0,"Cytosol"]
["dUTP[c]","2'-Deoxyuridine 5'-triphosphate (dUTP)","C9H15N2O14P3","C9H15N2O14P3",0,"Cytosol"]
["dXYLL5P[c]","1-Deoxy-D-xylulose 5-phosphate","C5H11O7P","C5H11O7P",0,"Cytosol"]
["E4P[c]","D-Erythrose 4-phosphate","C4H9O7P","C4H9O7P",0,"Cytosol"]
["ENITRN[c]","Ethylnitronate","C2H4NO2","C2H4NO2",0,"Cytosol"]
["ENZ_CYS[c]","Thiamine biosynthesis intermediate 2","C4H6N2O2SR2","C4H6N2O2SR2",0,"Cytosol"]
["ENZ_SLUFA_CYS[c]","[Enzyme]-S-sulfanylcysteine","C4H6N2O2S2R2","C4H6N2O2S2R2",0,"Cytosol"]
["ENZN6_LPL[c]","Enzyme N6-(lipoyl)lysine","C8H14NOS2R","C8H14NOS2R",0,"Cytosol"]
["ENZNE_DHYLPL[c]","Enzyme N6-(dihydrolipoyl)lysine","C8H16NOS2R","C8H16NOS2R",0,"Cytosol"]
["EPMLBIOS[c]","Epimelibiose","C12H22O11","C12H22O11",0,"Cytosol"]
["ERY_HYGLU[c]","L-erythro-4-Hydroxyglutamate","C5H9NO5","C5H9NO5",0,"Cytosol"]
["ERY_IMDZ_GLYCP[c]","D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate, D-erythro-Imidazole-glycerol 3-phosphate, D-erythro-Imidazole-glycerol phosphate","C6H11N2O6P","C6H11N2O6P",0,"Cytosol"]
["ETH[c]","Ethanol","C2H6O","C2H6O",0,"Cytosol"]
["ETH[e]","Ethanol","C2H6O","C2H6O",0,"Extra-organism"]
["F1P[c]","D-Fructose 1-phosphate","C6H13O9P","C6H13O9P",0,"Cytosol"]
["F1P[e]","D-Fructose 1-phosphate","C6H13O9P","C6H13O9P",0,"Extra-organism"]
["F6P[c]","D-Fructose 6-phosphate","C6H13O9P","C6H13O9P",0,"Cytosol"]
["FAD[c]","Flavin adenine dinucleotide (FAD)","C27H33N9O15P2","C27H33N9O15P2",0,"Cytosol"]
["FADH2[c]","Reduced Flavin adenine dinucleotide (FADH2)","C27H35N9O15P2","C27H35N9O15P2",0,"Cytosol"]
["FAICAR[c]","1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide (FAICAR)","C10H15N4O9P","C10H15N4O9P",0,"Cytosol"]
["FAPYRM_NTP[c]","Formamidopyrimidine nucleoside triphosphate","C10H18N5O15P3","C10H18N5O15P3",0,"Cytosol"]
["FAR_PPi[c]","trans,trans-Farnesyl diphosphate","C15H28O7P2","C15H28O7P2",0,"Cytosol"]
["FBP[c]","D-Fructose 1,6-bisphosphate","C6H14O12P2","C6H14O12P2",0,"Cytosol"]
["Fe2[c]","Ferrous ion","Fe","Fe",0,"Cytosol"]
["Fe2[e]","Ferrous ion","Fe","Fe",0,"Extra-organism"]
["FGAM[c]","2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine","C8H16N3O8P","C8H16N3O8P",0,"Cytosol"]
["FGAR[c]","5'-Phosphoribosyl-N-formylglycinamide (FGAR)","C8H15N2O9P","C8H15N2O9P",0,"Cytosol"]
["FMN[c]","Flavin mononucleotide (FMN)","C17H21N4O9P","C17H21N4O9P",0,"Cytosol"]
["FMNH2[c]","Reduced FMN (FMNH2)","C17H23N4O9P","C17H23N4O9P",0,"Cytosol"]
["FOLNA[c]","5-Formyltetrahydrofolate","C20H23N7O7","C20H23N7O7",0,"Cytosol"]
["FOR[c]","Formate","CH2O2","CH2O2",0,"Cytosol"]
["FUCL1P[c]","L-Fuculose 1-phosphate","C6H13O8P","C6H13O8P",0,"Cytosol"]
["FUCL1P[e]","L-Fuculose 1-phosphate","C6H13O8P","C6H13O8P",0,"Extra-organism"]
["FUM[c]","Fumarate","C4H4O4","C4H4O4",0,"Cytosol"]
["FUM[e]","Fumarate","C4H4O4","C4H4O4",0,"Extra-organism"]
["G1P[c]","D-Glucose 1-phosphate","C6H13O9P","C6H13O9P",0,"Cytosol"]
["G6P[c]","D-Glucose 6-phosphate","C6H13O9P","C6H13O9P",0,"Cytosol"]
["GAL1P[c]","alpha-D-Galactose 1-phosphate","C6H13O9P","C6H13O9P",0,"Cytosol"]
["GALCS_GLYC[c]","Galactosylglycerol","C9H18O8","C9H18O8",0,"Cytosol"]
["GALS_CA[c]","D-Galactosylceramide","C25H46NO8R","C25H46NO8R",0,"Cytosol"]
["GAP[c]","D-Glyceraldehyde 3-phosphate","C3H7O6P","C3H7O6P",0,"Cytosol"]
["GAR[c]","5'-Phosphoribosylglycinamide (GAR)","C7H15N2O8P","C7H15N2O8P",0,"Cytosol"]
["gCARO[c]","gamma-Carotene","C40H56","C40H56",0,"Cytosol"]
["GDP[c]","Guanosine 5'-diphosphate (GDP)","C10H15N5O11P2","C10H15N5O11P2",0,"Cytosol"]
["GDP_MAN[c]","GDP-D-mannose","C16H25N5O16P2","C16H25N5O16P2",0,"Cytosol"]
["GLC_LACN[c]","D-Glucono-1,5-lactone","C6H10O6","C6H10O6",0,"Cytosol"]
["GLCN[c]","D-Gluconate","C6H12O7","C6H12O7",0,"Cytosol"]
["GLCN[e]","D-Gluconate","C6H12O7","C6H12O7",0,"Extra-organism"]
["GLCN6P[c]","6-Phospho-D-gluconate","C6H13O10P","C6H13O10P",0,"Cytosol"]
["GLCP[c]","sn-Glycerol 3-phosphate","C3H9O6P","C3H9O6P",0,"Cytosol"]
["GLCTN[c]","Galactan","(C12H20O11)n","(C12H20O11)n",0,"Cytosol"]
["GLOXT[c]","Glyoxylate","C2H2O3","C2H2O3",0,"Cytosol"]
["GLU_SA[c]","L-Glutamate 1-semialdehyde","C5H9NO3","C5H9NO3",0,"Cytosol"]
["GLUCSA1P[c]","alpha-D-Glucosamine 1-phosphate","C6H14NO8P","C6H14NO8P",0,"Cytosol"]
["GLUCSA1P[e]","alpha-D-Glucosamine 1-phosphate","C6H14NO8P","C6H14NO8P",0,"Extra-organism"]
["GLUSAP[c]","D-Glucosamine 6-phosphate","C6H14NO8P","C6H14NO8P",0,"Cytosol"]
["GLUSAP[e]","D-Glucosamine 6-phosphate","C6H14NO8P","C6H14NO8P",0,"Extra-organism"]
["GLUT_SA[c]","L-Glutamate 5-semialdehyde","C5H9NO3","C5H9NO3",0,"Cytosol"]
["GLUTAT[c]","glutathione",null,null,0,"Cytosol"]
["GLUTRCoA[c]","Glutaryl-CoA","C26H42N7O19P3S","C26H42N7O19P3S",0,"Cytosol"]
["GLY[c]","Glycogen","(C6H10O5)n","(C6H10O5)n",0,"Cytosol"]
["GLY3P[c]","1-Acyl-sn-glycerol 3-phosphate","C4H8O7PR","C4H8O7PR",0,"Cytosol"]
["GLYALD[c]","D-Glyceraldehyde","C3H6O3","C3H6O3",0,"Cytosol"]
["GLYCALD[c]","Glycolaldehyde","C2H4O2","C2H4O2",0,"Cytosol"]
["GLYCALD[e]","Glycolaldehyde","C2H4O2","C2H4O2",0,"Extra-organism"]
["GLYCRL[c]","Glycerol"," C3H8O3"," C3H8O3",0,"Cytosol"]
["GLYCRL[e]","Glycerol"," C3H8O3"," C3H8O3",0,"Extra-organism"]
["GMP[c]","Guanosine 5'-phosphate (GMP)","C10H14N5O8P","C10H14N5O8P",0,"Cytosol"]
["GRN_GRNPPi[c]","Geranylgeranyl diphosphate","C20H36O7P2","C20H36O7P2",0,"Cytosol"]
["GRN_PPi[c]","Geranyl diphosphate","C10H20O7P2","C10H20O7P2",0,"Cytosol"]
["GTP[c]","Guanosine 5'-triphosphate (GTP)","C10H16N5O14P3","C10H16N5O14P3",0,"Cytosol"]
["GUN[c]","Guanine","C5H5N5O","C5H5N5O",0,"Cytosol"]
["GUNS[c]","Guanosine","C10H13N5O5","C10H13N5O5",0,"Cytosol"]
["GUNS_3PPi_5TPi[c]","Guanosine 3'-diphosphate 5'-triphosphate","C10H18N5O20P5","C10H18N5O20P5",0,"Cytosol"]
["GUNSBP[c]","Guanosine 3'-diphosphate 5'-diphosphate","C10H17N5O17P4","C10H17N5O17P4",0,"Cytosol"]
["H[c]","Hydron","H","H",0,"Cytosol"]
["H[e]","Hydron","H","H",0,"Cytosol"]
["H2O[c]","Water","H2O","H2O",0,"Cytosol"]
["H2O[e]","Water","H2O","H2O",0,"Extra-organism"]
["H2O2[c]","Hydrogen peroxide","H2O2","H2O2",0,"Cytosol"]
["H2S[c]","Hydrogen sulfide","H2S","H2S",0,"Cytosol"]
["H2S[e]","Hydrogen sulfide","H2S","H2S",0,"Extra-organism"]
["H4MPT[c]","5,6,7,8-Tetrahydromethanopterin (H4MPT)","C30H45N6O16P","C30H45N6O16P",0,"Cytosol"]
["HADPCoA[c]","3-hydroxyadipyl-CoA","C27H39N7O20P3S","C27H39N7O20P3S",0,"Cytosol"]
["HCARB[c]","Holo-[carboxylase]","C17H27N5O4SR2","C17H27N5O4SR2",0,"Cytosol"]
["HCIT[c]","Homocitrate","C7H10O7","C7H10O7",0,"Cytosol"]
["HCO3[c]","Bicarbonate","HCO3","HCO3",0,"Cytosol"]
["HCO3[e]","Bicarbonate","HCO3","HCO3",0,"Extra-organism"]
["HEME[c]","Heme","C34H32FeN4O4","C34H32FeN4O4",0,"Cytosol"]
["HEME[e]","Heme","C34H32FeN4O4","C34H32FeN4O4",0,"Extra-organism"]
["HEMO[c]","Heme O","C49H58FeN4O5","C49H58FeN4O5",0,"Cytosol"]
["HICTR[c]","Homoisocitrate","C7H10O7","C7H10O7",0,"Cytosol"]
["HISDPi[c]","L-Histidinol phosphate","C6H12N3O4P","C6H12N3O4P",0,"Cytosol"]
["HOBYRNA[c]","Hydrogenobyrinate","C45H60N4O14","C45H60N4O14",0,"Cytosol"]
["HOBYRNDA[c]","Hydrogenobyrinate diamide","C45H62N6O12","C45H62N6O12",0,"Cytosol"]
["HVCoA[c]","(R)-3-hydroxyvaleryl-CoA","C26H40N7O18P3S","C26H40N7O18P3S",0,"Cytosol"]
["HXTHN[c]","Hypoxanthine","C5H4N4O","C5H4N4O",0,"Cytosol"]
["HY_AC[c]","Glycolate","C2H4O3","C2H4O3",0,"Cytosol"]
["HY_AC[e]","Glycolate","C2H4O3","C2H4O3",0,"Extra-organism"]
["HY_BNZA[c]","4-Hydroxybenzoate","C7H6O3","C7H6O3",0,"Cytosol"]
["HY_DECCoA[c]","(S)-3-Hydroxydecanoyl-CoA","C31H54N7O18P3S","C31H54N7O18P3S",0,"Cytosol"]
["HY_DODECCoA[c]","(S)-3-Hydroxydodecanoyl-CoA","C33H58N7O18P3S","C33H58N7O18P3S",0,"Cytosol"]
["HY_MBILN[c]","Hydroxymethylbilane","C40H46N4O17","C40H46N4O17",0,"Cytosol"]
["HY_MBUTEPPi[c]","1-Hydroxy-2-methyl-2-butenyl 4-diphosphate; (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate; (E)-4-Hydroxy-3-methylbut-2-en-1-yl diphosphate","C5H12O8P2","C5H12O8P2",0,"Cytosol"]
["HY_MBUTRCoA[c]","(S)-3-Hydroxy-2-methylbutyryl-CoA","C26H44N7O18P3S","C26H44N7O18P3S",0,"Cytosol"]
["HY_OCTCoA[c]","(S)-3-Hydroxyoctanoyl-CoA","C29H50N7O18P3S","C29H50N7O18P3S",0,"Cytosol"]
["HY_OGLUTR[c]","D-4-Hydroxy-2-oxoglutarate","C5H6O6","C5H6O6",0,"Cytosol"]
["HY_PhAC[c]","4-Hydroxyphenylacetate","C8H8O3","C8H8O3",0,"Cytosol"]
["HY_PPREBNZA[c]","4-Hydroxy-3-polyprenylbenzoate","C12H14O3(C5H8)n","C12H14O3(C5H8)n",0,"Cytosol"]
["HY_PYR[c]","Hydroxypyruvate","C3H4O4","C3H4O4",0,"Cytosol"]
["HY_SUCC_CYCHEXDE_CARBA[c]","(1R,6R)-6-Hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate (SHCHC)","C11H12O6","C11H12O6",0,"Cytosol"]
["HY_THR[c]","4-Hydroxy-L-threonine","C4H9NO4","C4H9NO4",0,"Cytosol"]
["HYGLU_SA[c]","L-4-Hydroxyglutamate semialdehyde","C5H9NO4","C5H9NO4",0,"Cytosol"]
["HYHEPTDENA[c]","2-Hydroxyhepta-2,4-dienedioate","C7H8O5","C7H8O5",0,"Cytosol"]
["HYIBUTRA[c]","(S)-3-Hydroxyisobutyrate","C4H8O3","C4H8O3",0,"Cytosol"]
["HYIBUTRCoA[c]","(S)-3-Hydroxyisobutyryl-CoA","C25H42N7O18P3S","C25H42N7O18P3S",0,"Cytosol"]
["HYM_GLUTRCoA[c]","(S)-3-Hydroxy-3-methylglutaryl-CoA","C27H44N7O20P3S","C27H44N7O20P3S",0,"Cytosol"]
["HYPh_PYR[c]","p-Hydroxyphenylpyruvate","C9H8O4","C9H8O4",0,"Cytosol"]
["I110[c]","9-methyldecanoate (iso-11:0)",null,null,0,"Cytosol"]
["I130[c]","11-Methyldodecanoate (iso-13:0)",null,null,0,"Cytosol"]
["I150[c]","13-Methyltetradecanoate (iso-15:0)",null,null,0,"Cytosol"]
["I150CoA[c]","Iso-C15:0 CoA","C36H60N7O17P3S1","C36H60N7O17P3S1",0,"Cytosol"]
["I160[c]","14-Methylpentadecanoate (iso-16:0)",null,null,0,"Cytosol"]
["I160CoA[c]","Iso-C16:0 CoA","C37H62N7O17P3S1","C37H62N7O17P3S1",0,"Cytosol"]
["I170[c]","15-Methyl hexadecenoate (iso-17:0)",null,null,0,"Cytosol"]
["I170CoA[c]","Iso-C17:0 CoA","C38H64N7O17P3S1","C38H64N7O17P3S1",0,"Cytosol"]
["ICIT[c]","Isocitrate","C6H8O7","C6H8O7",0,"Cytosol"]
["IDHY_CRVN[c]"," (1R,4S)-Iso-dihydrocarvone","C10H16O","C10H16O",0,"Cytosol"]
["IDP[c]","Inosine 5'-diphosphate (IDP)","C10H14N4O11P2","C10H14N4O11P2",0,"Cytosol"]
["IMAC[c]","2-iminoacetate","C2H2NO2","C2H2NO2",0,"Cytosol"]
["IMALT[c]","Isomaltose",null,null,0,"Cytosol"]
["IMALT[e]","Isomaltose",null,null,0,"Extra-organism"]
["IMASP[c]","Iminoaspartate","C4H5NO4","C4H5NO4",0,"Cytosol"]
["IMDZ_AALD[c]","Imidazole-4-acetaldehyde","C5H6N2O","C5H6N2O",0,"Cytosol"]
["IMDZ_AC[c]","4-Imidazoleacetate","C5H6N2O2","C5H6N2O2",0,"Cytosol"]
["IMDZ_ACLP[c]","Imidazole-acetol phosphate","C6H9N2O5P","C6H9N2O5P",0,"Cytosol"]
["IMP[c]","Inosine monophosphate (IMP)","C10H13N4O8P","C10H13N4O8P",0,"Cytosol"]
["IND[c]","Indole","C8H7N","C8H7N",0,"Cytosol"]
["IND_GLYP[c]","Indoleglycerol phosphate","C11H14NO6P","C11H14NO6P",0,"Cytosol"]
["INSN[c]","Inosine","C10H12N4O5","C10H12N4O5",0,"Cytosol"]
["IPEN_PPi[c]","Isopentenyl diphosphate","C5H12O7P2","C5H12O7P2",0,"Cytosol"]
["IPRO_MAL[c]","(2S)-2-Isopropylmalate","C7H12O5","C7H12O5",0,"Cytosol"]
["IPRO_MALE[c]","2-Isopropylmaleate","C7H10O4","C7H10O4",0,"Cytosol"]
["IPROP_MAL[c]","(2R,3S)-3-Isopropylmalate","C7H12O5","C7H12O5",0,"Cytosol"]
["IPROP_OSUCC[c]","(2S)-2-Isopropyl-3-oxosuccinate","C7H10O5","C7H10O5",0,"Cytosol"]
["ITP[c]","Inosine 5'-triphosphate (ITP)","C10H15N4O14P3","C10H15N4O14P3",0,"Cytosol"]
["IVCoA[c]","Isovaleryl-CoA","C26H44N7O17P3S","C26H44N7O17P3S",0,"Cytosol"]
["KVCoA[c]","beta-ketovaleryl-CoA","C26H38N7O18P3S","C26H38N7O18P3S",0,"Cytosol"]
["L_ALA[c]","L-Alanine","C3H7NO2","C3H7NO2",0,"Cytosol"]
["L_ALA[e]","L-Alanine","C3H7NO2","C3H7NO2",0,"Extra-organism"]
["L_ARG[c]","L-Arginine","C6H14N4O2","C6H14N4O2",0,"Cytosol"]
["L_ARG[e]","L-Arginine","C6H14N4O2","C6H14N4O2",0,"Extra-organism"]
["L_ARG_SUCC[c]","L-Argininosuccinate","C10H18N4O6","C10H18N4O6",0,"Cytosol"]
["L_ASN[c]","L-Asparagine","C4H8N2O3","C4H8N2O3",0,"Cytosol"]
["L_ASN[e]","L-Asparagine","C4H8N2O3","C4H8N2O3",0,"Extra-organism"]
["L_ASP[c]","L-Aspartate","C4H7NO4","C4H7NO4",0,"Cytosol"]
["L_ASP[e]","L-Aspartate","C4H7NO4","C4H7NO4",0,"Extra-organism"]
["L_CYS[c]","L-Cysteine","C3H7NO2S","C3H7NO2S",0,"Cytosol"]
["L_CYS[e]","L-Cysteine","C3H7NO2S","C3H7NO2S",0,"Extra-organism"]
["L_CYSTA[c]","L-Cysteate","C3H7NO5S","C3H7NO5S",0,"Cytosol"]
["L_CYSTHNN[c]","L-Cystathionine","C7H14N2O4S","C7H14N2O4S",0,"Cytosol"]
["L_GLN[c]","L-Glutamine","C5H10N2O3","C5H10N2O3",0,"Cytosol"]
["L_GLU[c]","L-Glutamate","C5H9NO4","C5H9NO4",0,"Cytosol"]
["L_GLU[e]","L-Glutamate","C5H9NO4","C5H9NO4",0,"Extra-organism"]
["L_GLUT5P[c]","L-Glutamyl 5-phosphate","C5H10NO7P","C5H10NO7P",0,"Cytosol"]
["L_GLY[c]","Glycine","C2H5NO2","C2H5NO2",0,"Cytosol"]
["L_GLY[e]","Glycine","C2H5NO2","C2H5NO2",0,"Extra-organism"]
["L_HCYS[c]","L-Homocysteine","C4H9NO2S","C4H9NO2S",0,"Cytosol"]
["L_HCYS[e]","L-Homocysteine","C4H9NO2S","C4H9NO2S",0,"Extra-organism"]
["L_HIS[c]","L-Histidine","C6H9N3O2","C6H9N3O2",0,"Cytosol"]
["L_HISDAL[c]","L-Histidinal","C6H9N3O","C6H9N3O",0,"Cytosol"]
["L_HISN[c]","L-Histidinol","C6H11N3O","C6H11N3O",0,"Cytosol"]
["L_HSER[c]","L-Homoserine","C4H9NO3","C4H9NO3",0,"Cytosol"]
["L_ILE[c]","L-Isoleucine","C6H13NO2","C6H13NO2",0,"Cytosol"]
["L_ILE[e]","L-Isoleucine","C6H13NO2","C6H13NO2",0,"Extra-organism"]
["L_LEU[c]","L-Leucine","C6H13NO2","C6H13NO2",0,"Cytosol"]
["L_LEU[e]","L-Leucine","C6H13NO2","C6H13NO2",0,"Extra-organism"]
["L_LYS[c]","L-Lysine","C6H14N2O2","C6H14N2O2",0,"Cytosol"]
["L_LYS[e]","L-Lysine","C6H14N2O2","C6H14N2O2",0,"Extra-organism"]
["L_MET[c]","L-Methionine","C5H11NO2S","C5H11NO2S",0,"Cytosol"]
["L_MET[e]","L-Methionine","C5H11NO2S","C5H11NO2S",0,"Extra-organism"]
["L_PHE[c]","L-Phenylalanine","C9H11NO2","C9H11NO2",0,"Cytosol"]
["L_PHE[e]","L-Phenylalanine","C9H11NO2","C9H11NO2",0,"Extra-organism"]
["L_PRO[c]","L-Proline","C5H9NO2","C5H9NO2",0,"Cytosol"]
["L_PRO[e]","L-Proline","C5H9NO2","C5H9NO2",0,"Extra-organism"]
["L_SER[c]","L-Serine","C3H7NO3","C3H7NO3",0,"Cytosol"]
["L_SER[e]","L-Serine","C3H7NO3","C3H7NO3",0,"Extra-organism"]
["L_THR[c]","L-Threonine","C4H9NO3","C4H9NO3",0,"Cytosol"]
["L_THR[e]","L-Threonine","C4H9NO3","C4H9NO3",0,"Extra-organism"]
["L_TRP[c]","L-Tryptophan","C11H12N2O2","C11H12N2O2",0,"Cytosol"]
["L_TRP[e]","L-Tryptophan","C11H12N2O2","C11H12N2O2",0,"Extra-organism"]
["L_TYR[c]","L-Tyrosine","C9H11NO3","C9H11NO3",0,"Cytosol"]
["L_TYR[e]","L-Tyrosine","C9H11NO3","C9H11NO3",0,"Extra-organism"]
["L_VAL[c]","L-Valine","C5H11NO2","C5H11NO2",0,"Cytosol"]
["L_VAL[e]","L-Valine","C5H11NO2","C5H11NO2",0,"Extra-organism"]
["LAC[c]","L-Lactate","C3H6O3","C3H6O3",0,"Cytosol"]
["LAC[e]","L-Lactate","C3H6O3","C3H6O3",0,"Extra-organism"]
["LACGLUT[c]","Lactoylglutathione",null,null,0,"Cytosol"]
["LACTS[c]","Lactose","C12H22O11","C12H22O11",0,"Cytosol"]
["LACTS[e]","Lactose",null,null,0,"Extra-organism"]
["LALD[c]","(S)-Lactaldehyde","C3H6O2","C3H6O2",0,"Cytosol"]
["LCPN[c]","Lycopene","C40H56","C40H56",0,"Cytosol"]
["LP_ACP[c]","Lipoyl-[acp]","C8H13OS3R","C8H13OS3R",0,"Cytosol"]
["LPP[c]","Lipoylprotein","C8H14NOS2R","C8H14NOS2R",0,"Cytosol"]
["LYPCHOL[c]","Lysophosphatidylcholine",null,null,0,"Cytosol"]
["M_INS[c]","D-myo-Inositol","C6H12O6","C6H12O6",0,"Cytosol"]
["M26_DAP[c]","meso-2,6-Diaminoheptanedioate","C7H14N2O4","C7H14N2O4",0,"Cytosol"]
["M6P[c]","D-Mannose 6-phosphate","C6H13O9P","C6H13O9P",0,"Cytosol"]
["M6P[e]","D-Mannose 6-phosphate","C6H13O9P","C6H13O9P",0,"Extra-organism"]
["MAACCoA[c]","2-Methylacetoacetyl-CoA","C26H42N7O18P3S","C26H42N7O18P3S",0,"Cytosol"]
["MACRYCoA[c]","Methylacrylyl-CoA","C25H40N7O17P3S","C25H40N7O17P3S",0,"Cytosol"]
["MAL[c]","L-Malate","C4H6O5","C4H6O5",0,"Cytosol"]
["MAL[e]","L-Malate","C4H6O5","C4H6O5",0,"Extra-organism"]
["MAL_SA[c]","Malonate semialdehyde","C3H4O3","C3H4O3",0,"Cytosol"]
["MALCoA[c]","Malonyl-CoA","C24H38N7O19P3S","C24H38N7O19P3S",0,"Cytosol"]
["MALT[c]","Maltose","C12H22O11","C12H22O11",0,"Cytosol"]
["MALT[e]","Maltose","C12H22O11","C12H22O11",0,"Extra-organism"]
["MALYCoA[c]","(3S)-3-carboxy-3-hydroxypropionyl-CoA","C25H40N7O20P3S","C25H40N7O20P3S",0,"Cytosol"]
["MAN1P[c]","D-Mannose 1-phosphate","C6H13O9P","C6H13O9P",0,"Cytosol"]
["MAN1P[e]","D-Mannose 1-phosphate","C6H13O9P","C6H13O9P",0,"Extra-organism"]
["MANNPGLYCT[c]","2-(alpha-D-Mannosyl)-3-phosphoglycerate","C9H17O12P","C9H17O12P",0,"Cytosol"]
["MANNTRIS[c]","Mannotriose","C18H32O16","C18H32O16",0,"Cytosol"]
["MBUT_ENCoA[c]","2-Methylbut-2-enoyl-CoA","C26H42N7O17P3S","C26H42N7O17P3S",0,"Cytosol"]
["MBUTNCoA[c]","(S)-2-Methylbutanoyl-CoA","C26H44N7O17P3S","C26H44N7O17P3S",0,"Cytosol"]
["MCROCoA[c]","3-Methylcrotonyl-CoA","C26H42N7O17P3S","C26H42N7O17P3S",0,"Cytosol"]
["MEROL_CYCPPi[c]","2-C-Methyl-D-erythritol 2,4-cyclodiphosphate","C5H12O9P2","C5H12O9P2",0,"Cytosol"]
["MEROLPi[c]","2-C-Methyl-D-erythritol 4-phosphate","C5H13O7P","C5H13O7P",0,"Cytosol"]
["METHF[c]","5,10-Methenyltetrahydrofolate","C20H22N7O6","C20H22N7O6",0,"Cytosol"]
["METHMPTR[c]","5,10-Methylenetetrahydromethanopterin","C31H45N6O16P","C31H45N6O16P",0,"Cytosol"]
["METPPHOL[c]",{"$nulls":3},0,"Cytosol"]
["Mg[c]","Magnesium","Mg","Mg",0,"Cytosol"]
["Mg[e]","Magnesium","Mg","Mg",0,"Extra-organism"]
["Mg_PPPHYR[c]","Magnesium protoporphyrin","C34H32MgN4O4","C34H32MgN4O4",0,"Cytosol"]
["MGDG[c]","monoglucosyl-1,2 diacylglycerol",null,null,0,"Cytosol"]
["MGLX[c]","Methylglyoxal","C3H4O2","C3H4O2",0,"Cytosol"]
["mINS3P[c]","1D-myo-Inositol 3-phosphate","C6H13O9P","C6H13O9P",0,"Cytosol"]
["MLBIOS[c]","Melibiose","C12H22O11","C12H22O11",0,"Cytosol"]
["MLBTL[c]","Melibiitol","C12H24O11","C12H24O11",0,"Cytosol"]
["MMAL[c]","Methylmalonate","C4H6O4","C4H6O4",0,"Cytosol"]
["MMAL_SA[c]","(S)-Methylmalonate semialdehyde","C4H6O3","C4H6O3",0,"Cytosol"]
["MMALCoA[c]","(S)-Methylmalonyl-CoA","C25H40N7O19P3S","C25H40N7O19P3S",0,"Cytosol"]
["MQ[c]","Menaquinone","C16H16O2(C5H8)n","C16H16O2(C5H8)n",0,"Cytosol"]
["MQL[c]","Menaquinol","C16H18O2(C5H8)n","C16H18O2(C5H8)n",0,"Cytosol"]
["MTA[c]","5'-Methylthioadenosine","C11H15N5O3S","C11H15N5O3S",0,"Cytosol"]
["MTH_RIB[c]","5-Methylthio-D-ribose","C6H12O4S","C6H12O4S",0,"Cytosol"]
["MTh_RIB1P[c]","S-Methyl-5-thio-D-ribose 1-phosphate","C6H13O7PS","C6H13O7PS",0,"Cytosol"]
["MTh_RIBL1P[c]","S-Methyl-5-thio-D-ribulose 1-phosphate","C6H13O7PS","C6H13O7PS",0,"Cytosol"]
["MURAC_ALA_GLU_LYS_ALA_ALA_DP_UNDECP[c]","MurAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala)-diphospho- undecaprenol","C86H143N7O21P2","C86H143N7O21P2",0,"Cytosol"]
["N2AC_L_LYS[c]","N2-Acetyl-L-lysine","C8H16N2O3","C8H16N2O3",0,"Cytosol"]
["NAD[c]","Nicotinamide adenine dinucleotide (NAD)","C21H28N7O14P2","C21H28N7O14P2",0,"Cytosol"]
["NADH[c]","Nicotinamide adenine dinucleotide (NADH)","C21H29N7O14P2","C21H29N7O14P2",0,"Cytosol"]
["NADP[c]","Nicotinamide adenine dinucleotide phosphate (NADP)","C21H29N7O17P3","C21H29N7O17P3",0,"Cytosol"]
["NADPH[c]","Reduced nicotinamide adenine dinucleotide phosphate (NADPH)","C21H30N7O17P3","C21H30N7O17P3",0,"Cytosol"]
["NAMD[c]","Nicotinamide","C6H6N2O","C6H6N2O",0,"Cytosol"]
["NC_D_RNUC[c]","Nicotinate D-ribonucleotide","C11H15NO9P","C11H15NO9P",0,"Cytosol"]
["NH4[c]","Ammonia","NH4","NH4",0,"Cytosol"]
["NH4[e]","Ammonia","NH4","NH4",0,"Extra-organism"]
["NIA[c]","Nicotinate","C6H5NO2","C6H5NO2",0,"Cytosol"]
["NICRIB[c]","Nicotinate D-ribonucleoside","C11H14NO6","C11H14NO6",0,"Cytosol"]
["NMN[c]","Nicotinamide mononucleotide","C11H15N2O8P","C11H15N2O8P",0,"Cytosol"]
["NO2[c]","Nitrite","HNO2","HNO2",0,"Cytosol"]
["NRSPENE[c]","Neurosporene","C40H58","C40H58",0,"Cytosol"]
["O_FRDX[c]","Oxidized ferredoxin",null,null,0,"Cytosol"]
["O_TRED[c]","Oxidized thioredoxin","C10H12N4O4S2R4","C10H12N4O4S2R4",0,"Cytosol"]
["O2[c]","Oxygen","O2","O2",0,"Cytosol"]
["O2[e]","Oxygen","O2","O2",0,"Extra-organism"]
["OAC[c]","Oxaloacetate","C4H4O5","C4H4O5",0,"Cytosol"]
["OAC_HSER[c]","O-Acetyl-L-homoserine","C6H11NO4","C6H11NO4",0,"Cytosol"]
["OAC_SER[c]","O-Acetyl-L-serine","C5H9NO4","C5H9NO4",0,"Cytosol"]
["OADPCoA[c]","3-oxoadipyl-CoA","C27H37N7O20P3S","C27H37N7O20P3S",0,"Cytosol"]
["OCT_ACP[c]","Octanoyl-[acp]","C8H15OSR","C8H15OSR",0,"Cytosol"]
["ODHSCoA[c]","3-oxo-5,6-dehydrosuberyl-CoA","C29H39N7O20P3S","C29H39N7O20P3S",0,"Cytosol"]
["ODHSCoASA[c]","3-oxo-5,6-dehydrosuberyl-CoA semialdehyde","C29H40N7O19P3S","C29H40N7O19P3S",0,"Cytosol"]
["OHEPEDA[c]","2-Oxohept-3-enedioate","C7H8O5","C7H8O5",0,"Cytosol"]
["OP_HSER[c]","O-Phospho-L-homoserine","C4H10NO6P","C4H10NO6P",0,"Cytosol"]
["OPACCoA[c]","2-oxepin-2(3H)-ylideneacetyl-CoA","C29H38N7O18P3S","C29H38N7O18P3S",0,"Cytosol"]
["OPHY_THR[c]","O-Phospho-4-hydroxy-L-threonine","C4H10NO7P","C4H10NO7P",0,"Cytosol"]
["ORT[c]","L-Ornithine","C5H12N2O2","C5H12N2O2",0,"Cytosol"]
["ORTA[c]","Orotate","C5H4N2O4","C5H4N2O4",0,"Cytosol"]
["ORTD5P[c]","Orotidine 5'-phosphate","C10H13N2O11P","C10H13N2O11P",0,"Cytosol"]
["OXLGLUTR[c]","Oxaloglutarate","C7H8O7","C7H8O7",0,"Cytosol"]
["OXLSUCC[c]","Oxalosuccinate","C6H6O7","C6H6O7",0,"Cytosol"]
["PALT[c]","Paltinose",null,null,0,"Cytosol"]
["PALT[e]","Paltinose",null,null,0,"Extra-organism"]
["PANTA[c]","(R)-Pantoate","C6H12O4","C6H12O4",0,"Cytosol"]
["PANTE4Pi[c]","D-Pantetheine 4'-phosphate","C11H23N2O7PS","C11H23N2O7PS",0,"Cytosol"]
["PANTO[c]","(R)-Pantothenate","C9H17NO5","C9H17NO5",0,"Cytosol"]
["PAP[c]","Phosphoadenosine phosphate","C10H15N5O10P2","C10H15N5O10P2",0,"Cytosol"]
["PAPS[c]","3'-Phosphoadenylyl sulfate (PAPS)","C10H15N5O13P2S","C10H15N5O13P2S",0,"Cytosol"]
["PBDIOL[c]","2-polyprenyl-6-hydroxyphenol",null,null,0,"Cytosol"]
["PCHOL[c]","phosphatidylcholine",null,null,0,"Cytosol"]
["PCYTPPi_MEROL[c]","2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol","C14H26N3O17P3","C14H26N3O17P3",0,"Cytosol"]
["PDMETHA[c]","phosphatidyl-N-dimethylethanolamine",null,null,0,"Cytosol"]
["PEP[c]","Phosphoenolpyruvate","C3H5O6P","C3H5O6P",0,"Cytosol"]
["PETHA[c]","Phosphatidylethanolamine","C7H12NO8PR2","C7H12NO8PR2",0,"Cytosol"]
["PGLY[c]","phosphatidylglycerol",null,null,0,"Cytosol"]
["PGLYP[c]","phosphatidylglycerophosphate",null,null,0,"Cytosol"]
["PhAC[c]","Phenylacetate","C8H8O2","C8H8O2",0,"Cytosol"]
["PhACoA[c]","Phenylacetyl-CoA","C29H42N7O17P3S","C29H42N7O17P3S",0,"Cytosol"]
["PhALD[c]","Phenylacetaldehyde",null,null,0,"Cytosol"]
["PHB[c]","Polyhydroxybutyrate",null,null,0,"Cytosol"]
["PHB[e]","polyhydroxybutyrate",null,null,0,"Extra-organism"]
["PHD[c]","Polyhydroxydecanoate",null,null,0,"Cytosol"]
["PHD[e]","Polyhydroxydecanoate",null,null,0,"Extra-organism"]
["PHDD[c]","Polyhydodroxydecanoate",null,null,0,"Cytosol"]
["PHDD[e]","Polyhydodroxydecanoate",null,null,0,"Extra-organism"]
["PHFLN[c]","Phytofluene","C40H62","C40H62",0,"Cytosol"]
["PHO[c]","Polyhydroxyoctanoate",null,null,0,"Cytosol"]
["PHO[e]","Polyhydroxyoctanoate",null,null,0,"Extra-organism"]
["PHTEN[c]","Phytoene","C40H64","C40H64",0,"Cytosol"]
["PHV[c]","Polyhydroxyvalerate",null,null,0,"Cytosol"]
["PHV[e]","Polyhydroxyvalerate",null,null,0,"Extra-organism"]
["Pi[c]","Orthophosphate","H3PO4","H3PO4",0,"Cytosol"]
["Pi[e]","Orthophosphate","H3PO4","H3PO4",0,"Extra-organism"]
["PIM[c]","Pimelate","C7H12O4","C7H12O4",0,"Cytosol"]
["PIMCoA[c]","Pimeloyl-CoA","C28H46N7O19P3S","C28H46N7O19P3S",0,"Cytosol"]
["PINS[c]","1-phosphatidyl-inositol",null,null,0,"Cytosol"]
["PMETHA[c]","Phosphatidyl-N-methylethanolamine","C8H14NO8PR2","C8H14NO8PR2",0,"Cytosol"]
["PMINS3P[c]","1-phosphatidyl-1D-myo-inositol 3-phosphate",null,null,0,"Cytosol"]
["PN6_LPLYS[c]","Protein N6-(lipoyl)lysine","C8H14NOS2R","C8H14NOS2R",0,"Cytosol"]
["PN6_OCTLYS[c]","Protein N6-(octanoyl)lysine","C8H16NOR","C8H16NOR",0,"Cytosol"]
["PPANT[c]","(R)-4'-Phosphopantothenate","C9H18NO8P","C9H18NO8P",0,"Cytosol"]
["PPANTN_CYS[c]","(R)-4'-Phosphopantothenoyl-L-cysteine","C12H23N2O9PS","C12H23N2O9PS",0,"Cytosol"]
["PPBLGN[c]","Porphobilinogen","C10H14N2O4","C10H14N2O4",0,"Cytosol"]
["PPHA[c]","Prephenate","C10H10O6","C10H10O6",0,"Cytosol"]
["PPi[c]","Diphosphate","P2H4O7","P2H4O7",0,"Cytosol"]
["PPPHYR[c]","Protoporphyrin IX","C34H34N4O4","C34H34N4O4",0,"Cytosol"]
["PPPHYRGN[c]","Protoporphyrinogen IX","C34H40N4O4","C34H40N4O4",0,"Cytosol"]
["PPRE_MMOX_BNZQ[c]","2-Polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone","C13H16O3(C5H8)n","C13H16O3(C5H8)n",0,"Cytosol"]
["PPRE_MOX_BNZQ[c]","2-Polyprenyl-6-methoxy-1,4-benzoquinone","C12H14O3(C5H8)n","C12H14O3(C5H8)n",0,"Cytosol"]
["PPRENPhOL[c]","2-Polyprenylphenol","C11H14O(C5H8)n","C11H14O(C5H8)n",0,"Cytosol"]
["PPTD[c]","Phosphatidate","C5H7O8PR2","C5H7O8PR2",0,"Cytosol"]
["PPTD_SER[c]","Phosphatidyl-L-serine","C8H12NO10PR2","C8H12NO10PR2",0,"Cytosol"]
["PPYR[c]","Phenylpyruvate","C9H8O3","C9H8O3",0,"Cytosol"]
["PRCoA[c]","Propanoyl-CoA","C24H40N7O17P3S","C24H40N7O17P3S",0,"Cytosol"]
["PRCRN[c]","Precorrin 2","C42H48N4O16","C42H48N4O16",0,"Cytosol"]
["PRCRN3A[c]","Precorrin 3A","C43H50N4O16","C43H50N4O16",0,"Cytosol"]
["PRCRN3B[c]","Precorrin 3B","C43H50N4O17","C43H50N4O17",0,"Cytosol"]
["PRCRN4[c]","Precorrin 4","C44H52N4O17","C44H52N4O17",0,"Cytosol"]
["PRCRN5[c]","Precorrin 5","C45H54N4O17","C45H54N4O17",0,"Cytosol"]
["PRCRN6B[c]","Precorrin 6B","C44H56N4O16","C44H56N4O16",0,"Cytosol"]
["PRCRN8X[c]","Precorrin 8","C45H60N4O14","C45H60N4O14",0,"Cytosol"]
["PRIB_AMP[c]","Phosphoribosyl-AMP","C15H23N5O14P2","C15H23N5O14P2",0,"Cytosol"]
["PRIB_ATP[c]","Phosphoribosyl-ATP","C15H25N5O20P4","C15H25N5O20P4",0,"Cytosol"]
["PRIBS_DMBENZ_IMDZ[c]","N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole","C14H19N2O7P","C14H19N2O7P",0,"Cytosol"]
["PRIBSAMN[c]","5-Phosphoribosylamine","C5H12NO7P","C5H12NO7P",0,"Cytosol"]
["PRINS_AFORMA_PRIBS_IMDZ_CARBA[c]","5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)- imidazole-4-carboxamide","C15H25N5O15P2","C15H25N5O15P2",0,"Cytosol"]
["PRINSFORMA_PRIBS_IMDZ_CARBA[c]","N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D- ribosyl)-4-imidazolecarboxamide","C15H25N5O15P2","C15H25N5O15P2",0,"Cytosol"]
["PROP[c]","Propanoate","C3H6O2","C3H6O2",0,"Cytosol"]
["PROP_ADNSPi[c]","Propionyladenylate","C13H18N5O8P","C13H18N5O8P",0,"Cytosol"]
["PRPP[c]","5-Phospho-alpha-D-ribose 1-diphosphate","C5H13O14P3","C5H13O14P3",0,"Cytosol"]
["PSULFLAC[c]","(2R)-O-Phospho-3-sulfolactate","C3H7O9PS","C3H7O9PS",0,"Cytosol"]
["PUT[c]","Putrescine","C4H12N2","C4H12N2",0,"Cytosol"]
["PX[c]","N-acylphosphoethanolamine",null,null,0,"Cytosol"]
["PYR[c]","Pyruvate","C3H4O3","C3H4O3",0,"Cytosol"]
["PYRR_3HY_5CARB[c]","L-1-Pyrroline-3-hydroxy-5-carboxylate","C5H7NO3","C5H7NO3",0,"Cytosol"]
["PYRR5CARB[c]","L-1-Pyrroline-5-carboxylate","C5H7NO2","C5H7NO2",0,"Cytosol"]
["QA[c]","Quinolinate","C7H5NO4","C7H5NO4",0,"Cytosol"]
["R_FRDX[c]","Reduced ferredoxin",null,null,0,"Cytosol"]
["R_MMALCoA[c]","(R)-Methylmalonyl-CoA","C25H40N7O19P3S","C25H40N7O19P3S",0,"Cytosol"]
["R_TRED[c]","Reduced thioredoxin","C10H14N4O4S2R4","C10H14N4O4S2R4",0,"Cytosol"]
["R1P[c]","D-Ribose 1-phosphate","C5H11O8P","C5H11O8P",0,"Cytosol"]
["R5P[c]","D-Ribose 5-phosphate","C5H11O8P","C5H11O8P",0,"Cytosol"]
["RAFF[c]","Raffinose","C18H32O16","C18H32O16",0,"Cytosol"]
["RBFLV[c]","Riboflavin (Vitamin B2)","C17H20N4O6","C17H20N4O6",0,"Cytosol"]
["RBL5P[c]","D-Ribulose 5-phosphate","C5H11O8P","C5H11O8P",0,"Cytosol"]
["RDHY_MBUTNA[c]","(R)-2,3-Dihydroxy-3-methylbutanoate","C5H10O4","C5H10O4",0,"Cytosol"]
["RHY_BUTCoA[c]","(R)-3-Hydroxybutanoyl-CoA","C25H42N7O18P3S","C25H42N7O18P3S",0,"Cytosol"]
["RIBS_HCYS[c]","S-Ribosyl-L-homocysteine","C9H17NO6S","C9H17NO6S",0,"Cytosol"]
["RIBS_NCTA[c]","N-Ribosylnicotinamide","C11H15N2O5","C11H15N2O5",0,"Cytosol"]
["S[c]","Sulfur","S","S",0,"Cytosol"]
["S_ACLAC[c]","(S)-2-Acetolactate","C5H8O4","C5H8O4",0,"Cytosol"]
["SAHC[c]","S-Adenosyl-L-homocysteine","C14H20N6O5S","C14H20N6O5S",0,"Cytosol"]
["SAICAR[c]","1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole (SAICAR)","C13H19N4O12P","C13H19N4O12P",0,"Cytosol"]
["SAM[c]","S-Adenosyl-L-methionine (SAM)","C15H22N6O5S","C15H22N6O5S",0,"Cytosol"]
["SAMA[c]","S-Adenosylmethioninamine","C14H23N6O3S","C14H23N6O3S",0,"Cytosol"]
["SEDHEP7P[c]","D-Sedoheptulose 7-phosphate","C7H15O10P","C7H15O10P",0,"Cytosol"]
["SHEME[c]","Siroheme","C42H44FeN4O16","C42H44FeN4O16",0,"Cytosol"]
["SHK[c]","Shikimate","C7H10O5","C7H10O5",0,"Cytosol"]
["SHKP[c]","Shikimate 5-phosphate","C7H11O8P","C7H11O8P",0,"Cytosol"]
["SLF_ALA[c]","3-Sulfino-L-alanine","C3H7NO4S","C3H7NO4S",0,"Cytosol"]
["SO3[c]","Sulfite","H2SO3","H2SO3",0,"Cytosol"]
["SO3[e]","Sulfite","H2SO3","H2SO3",0,"Extra-organism"]
["SO4[c]","Sulfate","H2SO4","H2SO4",0,"Cytosol"]
["SO4[e]","Sulfate","H2SO4","H2SO4",0,"Extra-organism"]
["SORB[c]","D-Sorbitol","C6H14O6","C6H14O6",0,"Cytosol"]
["SORB[e]","D-Sorbitol","C6H14O6","C6H14O6",0,"Extra-organism"]
["SPR[c]","Spermine","C10H26N4","C10H26N4",0,"Cytosol"]
["SPRD[c]","Spermidine","C7H19N3","C7H19N3",0,"Cytosol"]
["SRHYCLR[c]","Sirohydrochlorin","C42H46N4O16","C42H46N4O16",0,"Cytosol"]
["STCYS[c]","Stachyose","C24H42O21","C24H42O21",0,"Cytosol"]
["STCYS[e]","Stachyose",null,null,0,"Extra-organism"]
["SUC[c]","Sucrose","C12H22O11","C12H22O11",0,"Cytosol"]
["SUC[e]","Sucrose","C12H22O11","C12H22O11",0,"Extra-organism"]
["SUCC[c]","Succinate","C4H6O4","C4H6O4",0,"Cytosol"]
["SUCC[e]","Succinate","C4H6O4","C4H6O4",0,"Extra-organism"]
["SUCC_BNZA[c]","2-Succinylbenzoate","C11H10O5","C11H10O5",0,"Cytosol"]
["SUCC_SA[c]","Succinate semialdehyde","C4H6O3","C4H6O3",0,"Cytosol"]
["SUCCoA[c]","Succinyl-CoA","C25H40N7O19P3S","C25H40N7O19P3S",0,"Cytosol"]
["SULFI_PYR[c]","3-Sulfinylpyruvate","C3H4O5S","C3H4O5S",0,"Cytosol"]
["SULFLAC[c]","(2R)-3-Sulfolactate","C3H6O6S","C3H6O6S",0,"Cytosol"]
["SULFO_PYR[c]","3-Sulfopyruvate","C3H4O6S","C3H4O6S",0,"Cytosol"]
["t_PPREPPi[c]","all-trans-Polyprenyl diphosphate","C5H12O7P2(C5H8)n","C5H12O7P2(C5H8)n",0,"Cytosol"]
["tbZXT[c]","Thermobiszeaxanthin","C78H124O14","C78H124O14",0,"Cytosol"]
["tCRTX[c]","Thermocryptoxanthin","C57H86O7","C57H86O7",0,"Cytosol"]
["THF[c]","5,6,7,8-Tetrahydrofolate","C19H23N7O6","C19H23N7O6",0,"Cytosol"]
["THF_GLUT[c]","THF-L-glutamate","C24H30N8O9","C24H30N8O9",0,"Cytosol"]
["tHY_PRO[c]","trans-4-Hydroxy-L-proline","C5H9NO3","C5H9NO3",0,"Cytosol"]
["THYM[c]","Thymine","C5H6N2O2","C5H6N2O2",0,"Cytosol"]
["THYMD[c]","Thymidine","C10H14N2O5","C10H14N2O5",0,"Cytosol"]
["THZ[c]","Thiazole",null,null,0,"Cytosol"]
["TM_AMBUTAL[c]","4-Trimethylammoniobutanal","C7H16NO","C7H16NO",0,"Cytosol"]
["TM_AMBUTAT[c]","4-Trimethylammoniobutanoate","C7H16NO2","C7H16NO2",0,"Cytosol"]
["TMP[c]","Thiamine monophosphate (TMP)","C12H18N4O4PS","C12H18N4O4PS",0,"Cytosol"]
["TOPYRM[c]","Toxopyrimidine","C6H9N3O","C6H9N3O",0,"Cytosol"]
["TPi[c]","Triphosphate","P3H5O10","P3H5O10",0,"Cytosol"]
["TPP[c]","Thiamine diphosphate (ThPP)","C12H19N4O7P2S","C12H19N4O7P2S",0,"Cytosol"]
["TRE[c]","Trehalose","C12H22O11","C12H22O11",0,"Cytosol"]
["TRE[e]","Trehalose","C12H22O11","C12H22O11",0,"Extra-organism"]
["TRE6P[c]","Trehalose 6-phosphate","C12H23O14P","C12H23O14P",0,"Cytosol"]
["TSFA[c]","Thiosulfate","HS2O3","HS2O3",0,"Cytosol"]
["tZXT[c]","Thermozeaxanthin","C59H90O8","C59H90O8",0,"Cytosol"]
["tZXT_GLU[c]","Thermozeaxanthin glucoside",null,null,0,"Cytosol"]
["UDP[c]","Uridine 5'-diphosphate (UDP)","C9H14N2O12P2","C9H14N2O12P2",0,"Cytosol"]
["UDP_AC_CARBVIN_GLUCSA[c]","UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine","C20H29N3O19P2","C20H29N3O19P2",0,"Cytosol"]
["UDP_AC_MANNA[c]","UDP-N-acetyl-D-mannosamine","C17H27N3O17P2","C17H27N3O17P2",0,"Cytosol"]
["UDP_ACMUR_ALA_GLU_DAPIM[c]","UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6- diaminopimelate","C35H55N7O26P2","C35H55N7O26P2",0,"Cytosol"]
["UDP_ACMUR_ALA_GLU_DAPIM_ALA_ALA[c]","UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl- D-alanine","C41H65N9O28P2","C41H65N9O28P2",0,"Cytosol"]
["UDP_ACMUR_ALA_GLU_LYS[c]","UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine","C34H55N7O24P2","C34H55N7O24P2",0,"Cytosol"]
["UDP_ACMURM[c]","UDP-N-acetylmuramate","C20H31N3O19P2","C20H31N3O19P2",0,"Cytosol"]
["UDP_ACMURM_ALA[c]","UDP-N-acetylmuramoyl-L-alanine","C23H36N4O20P2","C23H36N4O20P2",0,"Cytosol"]
["UDP_ACMURM_ALA_GLUT[c]","UDP-N-acetylmuramoyl-L-alanyl-D-glutamate","C28H43N5O23P2","C28H43N5O23P2",0,"Cytosol"]
["UDP_AGLUAM[c]","UDP-N-acetyl-D-glucosamine","C17H27N3O17P2","C17H27N3O17P2",0,"Cytosol"]
["UDP_GAL[c]","UDP-D-galactose","C15H24N2O17P2","C15H24N2O17P2",0,"Cytosol"]
["UDP_GLU[c]","UDP-D-glucose","C15H24N2O17P2","C15H24N2O17P2",0,"Cytosol"]
["UDP_MURAC_ALA_GLU_LYS_ALA_ALA[c]","UDPMurAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala)","C40H65N9O26P2","C40H65N9O26P2",0,"Cytosol"]
["UMP[c]","Uridine 5'-monophosphate (UMP)","C9H13N2O9P","C9H13N2O9P",0,"Cytosol"]
["Undp_ACMUR_ACGLSA_ALA_GLU_DAPIM_AALA[c]","Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L- alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine","C95H156N8O28P2","C95H156N8O28P2",0,"Cytosol"]
["Undp_ACMUR_ACGLSA_ALA_GLU_LYS_AALA[c]","Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L- alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine, GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)- diphosphoundecaprenol","C94H156N8O26P2","C94H156N8O26P2",0,"Cytosol"]
["Undp_ACMUR_ALA_GLU_DAPIM_AALA[c]","Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine","C87H143N7O23P2","C87H143N7O23P2",0,"Cytosol"]
["UPPHYRGN_I[c]","Uroporphyrinogen I","C40H44N4O16","C40H44N4O16",0,"Cytosol"]
["UPPHYRGN_III[c]","Uroporphyrinogen III","C40H44N4O16","C40H44N4O16",0,"Cytosol"]
["UppppU[c]","P1,P4-Bis(5'-uridyl) tetraphosphate (UppppU)","C18H26N4O23P4","C18H26N4O23P4",0,"Cytosol"]
["URA[c]","Uracil","C4H4N2O2","C4H4N2O2",0,"Cytosol"]
["URD[c]","Uridine","C9H12N2O6","C9H12N2O6",0,"Cytosol"]
["UREA[c]","Urea, Carbamide","CH4N2O","CH4N2O",0,"Cytosol"]
["UREA_CARB[c]","Urea-1-carboxylate","C2H4N2O3","C2H4N2O3",0,"Cytosol"]
["UREIDO_BUTR[c]","3-Ureidoisobutyrate","C5H10N2O3","C5H10N2O3",0,"Cytosol"]
["UTP[c]","Uridine 5'-triphosphate (UTP)","C9H15N2O15P3","C9H15N2O15P3",0,"Cytosol"]
["XMP[c]","Xanthosine 5'-phosphate (XMP)","C10H13N4O9P","C10H13N4O9P",0,"Cytosol"]
["XNTHS[c]","Xanthosine","C10H12N4O6","C10H12N4O6",0,"Cytosol"]
["XppppX[c]","P1,P4-Bis(5'-xanthosyl) tetraphosphate (XppppX)","C20H26N8O23P4","C20H26N8O23P4",0,"Cytosol"]
["XTHN[c]","Xanthine","C5H4N4O2","C5H4N4O2",0,"Cytosol"]
["XTP[c]","XTP","C10H15N4O15P3","C10H15N4O15P3",0,"Cytosol"]
["XYL5P[c]","D-Xylulose 5-phosphate","C5H11O8P","C5H11O8P",0,"Cytosol"]
["zCARO[c]","zeta-Carotene","C40H60","C40H60",0,"Cytosol"]
["ZXT[c]","Zeaxanthin","C40H56O2","C40H56O2",0,"Cytosol"]
["ZXT_GLU[c]","Zeaxanthin glucoside",null,null,0,"Cytosol"]
["dcSAM[c]","S-adenosyl 3-(methylthio)propylamine","C14H24N6O3S","C14H24N6O3S",0,"Cytosol"]
["apAGMT[c]","N1-aminopropylagmatine","C8H24N5","C8H24N5",0,"Cytosol"]
["tSPR[c]","Thermospermine","C10H26N4","C10H26N4",0,"Cytosol"]
["SPR[c]","Spermine","C10H26N4","C10H26N4",0,"Cytosol"]
["tPAM[c]","Thermopentamine","C13H33N5","C13H33N5",0,"Cytosol"]
["hCPAM[c]","Homocaldopentamine","C13H33N5","C13H33N5",0,"Cytosol"]
["hCHAM[c]","Homocaldohexanine","C16H40N6","C16H40N6",0,"Cytosol"]
["PDAM[c]","propane-1,3-diamine","C3H12N2","C3H12N2",0,"Cytosol"]
["NSPRD[c]","Norspermidine","C6H20N3","C6H20N3",0,"Cytosol"]
["TM[c]","Thermine","C9H28N4","C9H28N4",0,"Cytosol"]
["CPAM[c]","Caldopentamine","C12H36N5","C12H36N5",0,"Cytosol"]
["CHAM[c]","Caldohexanine","C15H44N6","C15H44N6",0,"Cytosol"]
["TRIAM[c]","Tris(3-aminopropyl)amine","C9H27N4","C9H27N4",0,"Cytosol"]
["TETAM[c]","Tetrakis(3-aminopropyl)ammonium","C12H36N5","C12H36N5",0,"Cytosol"]
["hSPRD[c]","sym-Homospermidine","C8H21N3","C8H21N3",0,"Cytosol"]
["hSPR[c]","Homospermine","C11H26N4",null,0,"Cytosol"]

{"sheet":"A3","index":3,"n_rows":10,"n_cols":5,"rows_kept":10,"flags":["formulas_cached_only"]}
["Gene locus","Current annotation ","Suggested annotation","Gene name","EC number"]
["TTC0107","putative α-glucosidase/glycoside hydrolase","α-glucosidase/ trehalose-6-phosphate hydrolase","aglH/treC","3.2.1.20/ 3.2.1.93"]
["TTC1591","2-oxoacid-ferredoxin oxidoreductase","Ketoisovalerate oxidoreductase","vorA","1.2.7.7"]
["TT_P0059","cytochrome P450","carotene β-hydroxylase","crtZ","1.14.13.129"]
["TT_P0061","hypothetical protein","acyltransferase","cruD","-"]
["TT_P0062","hypothetical protein","glucosyltransferase","cruC","-"]
["TTC0824","putative phosphoslipase","CDP-diacylglycerol-serine O-phosphatidyltransferase","pssA","2.7.8.8"]
["TTC1543","ribosomal protein S6 modification protein","alpha-aminoadipate acetyltransferase","lysX","6.3.2.-"]
["TTC1192","propionyl-CoA carboxylase subunit beta","methylcrotonoyl-CoA carboxylase","mccc1","6.4.1.4"]
["TTC1875","galactoside O-acetyltransferase","L-serine O-acetyltransferase","sat1","2.3.1.30"]

{"sheet":"A4","index":4,"n_rows":75,"n_cols":4,"rows_kept":75,"flags":["formulas_cached_only"]}
["Id","Name","Reaction","Subsystem"]
["R699","(R)-3-Hydroxybutanoyl-CoA:NADP+ oxidoreductase","H[c] + NADPH[c] + ACACoA[c]  <=> NADP[c] + RHY_BUTCoA[c] ","Butanoate metabolism"]
["R700","beta-ketothiolase ","ACoA[c] + PRCoA[c]  -> CoA[c] + KVCoA[c] ","Butanoate metabolism"]
["R701","(R)-3-Hydroxybutanoyl-CoA:NADP+ oxidoreductase","3 H[c] + NADPH[c] + KVCoA[c]  <=> NADP[c] + HVCoA[c] ","Butanoate metabolism"]
["R702","Acyltransferase","2 RHY_BUTCoA[c]  -> 2 CoA[c] + PHB[c] ","Butanoate metabolism"]
["R703","Acyltransferase","2 HVCoA[c]  -> CoA[c] + PHV[c] ","Butanoate metabolism"]
["R704","fatty acid synthesis; lumped","RHY_BUTCoA[c] + 2 ACoA[c] + 4 NADPH[c] + 4 H[c]  <=> 4 NADP[c] + HY_OCTCoA[c] + 2 H2O[c] + 2 CoA[c]","Butanoate metabolism"]
["R705","Acyltransferase","2 HY_OCTCoA[c]  -> 2 CoA[c] + PHO[c] ","Butanoate metabolism"]
["R706","fatty acid synthesis; lumped","HY_OCTCoA[c] + ACoA[c] + 2 NADPH[c] + 2 H[c]  <=> 2 NADP[c] + HY_DECCoA[c] + H2O[c] + CoA[c]","Butanoate metabolism"]
["R707","Acyltransferase","2 HY_DECCoA[c]  -> 2 CoA[c] + PHD[c] ","Butanoate metabolism"]
["R708","fatty acid synthesis; lumped","HY_DECCoA[c] + ACoA[c] + 2 NADPH[c] + 2 H[c]  <=> 2 NADP[c] + HY_DODECCoA[c] + H2O[c] + CoA[c]","Butanoate metabolism"]
["R709","Acyltransferase","2 HY_DODECCoA[c]  -> 2 CoA[c] + PHDD[c] ","Butanoate metabolism"]
["R688","beta-carotene hydroxylase","H[c] + NADH[c] + O2[c] + bCARO[c]  <=> NAD[c] + H2O[c] + CRTX[c] ","Carotenoid biosynthesis"]
["R689","beta-cryptoxanthin hydroxylase ","H[c] + NADH[c] + O2[c] + CRTX[c]  -> NAD[c] + ZXT[c] + H2O[c] ","Carotenoid biosynthesis"]
["R690","thermocryptoxanthin hydroxylase ","H[c] + NADH[c] + O2[c] + tCRTX[c]  -> NAD[c] + tZXT[c] + H2O[c] ","Carotenoid biosynthesis"]
["R691","beta-cryptoxanthin glucosyltransferase","CRTX[c] + UDP_GLU[c]  -> bCRTX_GLU[c] + UDP[c] +  H[c] ","Carotenoid biosynthesis"]
["R692","beta-cryptoxanthin acyltransferase (C11:0)","bCRTX_GLU[c] + 0.334 I150CoA[c] + 0.069 AI150CoA[c] + 0.047 I160CoA[c] + 0.014 C160CoA[c] + 0.0015 C161CoA[c] + 0.45 I170CoA[c] + 0.075 AI171CoA[c] -> tCRTX[c] + CoA[c] ","Carotenoid biosynthesis"]
["R693","zeaxanthin glucosyltransferase","ZXT[c] + UDP_GLU[c]  -> ZXT_GLU[c] + UDP[c] +  H[c] ","Carotenoid biosynthesis"]
["R694","zeaxanthin acyltransferase (C13:0)","ZXT_GLU[c] + 0.334 I150CoA[c] + 0.069 AI150CoA[c] + 0.047 I160CoA[c] + 0.014 C160CoA[c] + 0.0015 C161CoA[c] + 0.45 I170CoA[c] + 0.075 AI171CoA[c]  -> tZXT[c] + CoA[c] ","Carotenoid biosynthesis"]
["R695","thermozeaxanthin glucosyltransferase","tZXT[c] + UDP_GLU[c]  -> tZXT_GLU[c] + UDP[c] +  H[c] ","Carotenoid biosynthesis"]
["R696","thermozeaxanthin acyltransferase (C13-C13)","tZXT_GLU[c] + 0.334 I150CoA[c] + 0.069 AI150CoA[c] + 0.047 I160CoA[c] + 0.014 C160CoA[c] + 0.0015 C161CoA[c] + 0.45 I170CoA[c] + 0.075 AI171CoA[c]  -> tbZXT[c] + CoA[c] ","Carotenoid biosynthesis"]
["R571","trehalase","H2O[c] + TRE[c]  -> 2 D_GLC[c] ","Alternate Carbon Metabolism"]
["R066","sucrose glucohydrolase","H2O[c] + SUC[c]  -> D_GLC[c] + D_FRU[c] ","Alternate Carbon Metabolism"]
["R067","palatinose glucohydrolase","H2O[c] + PALT[c]  -> D_GLC[c] + D_FRU[c] ","Alternate Carbon Metabolism"]
["R371","maltose glucohydrolase","H2O[c] + MALT[c]  -> 2 D_GLC[c] ","Alternate Carbon Metabolism"]
["R372","maltose glucohydrolase","H2O[c] + IMALT[c]  -> 2 D_GLC[c] ","Alternate Carbon Metabolism"]
["R367","cellobiose glucohydrolase","H2O[c] + CELBS[c]  -> 2 D_GLC[c] ","Alternate Carbon Metabolism"]
["R004","ATP:D-glucose 6-phosphotransferase","ATP[c] + D_MAN[c]  -> ADP[c] + H[c] + M6P[c] ","Glycolysis/Gluconeogenesis"]
["R444","Thiamin diphosphate phosphohydrolase","H2O[c] + TPP[c]  -> Pi[c] + H[c] + TMP[c] ","Cofactor and Prosthetic Group Biosynthesis"]
["R512","carvone reductase","H[c] + CRVN[c]  -> IDHY_CRVN[c] ","Limonene and pinene degradation"]
["R538","protoheme IX farnesyltransferase","H2O[c] + FAR_PPi[c] + HEME[c]  -> PPi[c] + HEMO[c] ","Cofactor and Prosthetic Group Biosynthesis"]
["R558","citrullinase","H2O[c] + H[c] + CTRLN[c]  -> ORT[c] + CO2[c] + NH4[c] ","Arginine and Proline Metabolism"]
["R559","malate dehydrogenase (quinone)","MAL[c] + Q[c]  -> OAC[c] + QH2[c] ","Citric Acid Cycle"]
["R563","N2-acetyl-alpha-aminoadipate semialdehyde transaminase","L_GLU[c] + AC_AADP_SA[c]  -> AKG[c] + N2AC_L_LYS[c] ","Threonine and Lysine Metabolism"]
["R564","alpha-aminoadipate acetyltransferase","ACoA[c] + AADP[c]  <=> CoA[c] + H[c] + AC_AADP[c] ","Threonine and Lysine Metabolism"]
["R572","trehalose-6-phosphate hydrolase","H2O[c] + TRE6P[c]  -> D_GLC[c] + G6P[c] ","Alternate Carbon Metabolism"]
["R573","trehalose-6-phosphate phosphatase","H2O[c] + TRE6P[c]  -> Pi[c] + TRE[c] ","Alternate Carbon Metabolism"]
["R580","3-Methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)","ATP[c] + HCO3[c] + MCROCoA[c]  -> ADP[c] + Pi[c] + 3MGLUTNCoA[c] ","Valine, Leucine, and Isoleucine Metabolism"]
["R582","succinyl-CoA:acetoacetate CoA-transferase","SUCCoA[c] + AAC[c]  <=> SUCC[c] + ACACoA[c] ","Citric Acid Cycle"]
["R583","(S)-3-Hydroxyisobutyryl-CoA hydrolase","H2O[c] + HYIBUTRCoA[c]  <=> CoA[c] + HYIBUTRA[c] ","Valine, Leucine, and Isoleucine Metabolism"]
["R590","formate C-acetyltransferase","CoA[c] + PYR[c]  -> ACoA[c] + FOR[c] ","Pyruvate Metabolism"]
["R591","protoporphyrinogen IX dehydrogenase (menaquinone)","3 MQ[c] + PPPHYRGN[c]  -> PPPHYR[c] + 3 MQL[c] ","Cofactor and Prosthetic Group Biosynthesis"]
["R593","serine O-acetyltransferase","L_SER[c] + ACoA[c]  -> CoA[c] + OAC_SER[c] ","Cysteine and methionine metabolism"]
["R598","NADPH quinone reductase","H[c] + NADPH[c] + Q[c]  -> NADP[c] + QH2[c] ","Oxidative Phosphorylation"]
["R599","NADPH quinone reductase","H[c] + NADPH[c] + MQ[c]  -> NADP[c] + MQL[c] ","Oxidative Phosphorylation"]
["R600","2-dehydropantoate 2-reductase","H[c] + NADPH[c] + DHY_PAN[c]  -> NADP[c] + PANTA[c] ","Cofactor and Prosthetic Group Biosynthesis"]
["R606","mannose-1-phosphate guanylyltransferase","GTP[c] + H[c] + MAN1P[c]  -> PPi[c] + GDP_MAN[c] ","Alternate Carbon Metabolism"]
["R614","NAD+ kinase","ATP[c] + NAD[c]  -> NADP[c] + ADP[c] + H[c] ","Cofactor and Prosthetic Group Biosynthesis"]
["R616","thymidine kinase","ATP[c] + THYMD[c]  -> ADP[c] + H[c] + dTMP[c] ","Nucleotide Salvage Pathway"]
["R619","carbamate kinase","ADP[c] + H[c] + CARB_Pi[c]  -> ATP[c] + CO2[c] + NH4[c] ","Unassigned"]
["R623","NAD+ diphosphatase","NAD[c] + H2O[c]  -> 2 H[c] + AMP[c] + NMN[c] ","Cofactor and Prosthetic Group Biosynthesis"]
["R624","NMN nucleosidase","H2O[c] + NMN[c]  -> H[c] + R5P[c] + NAMD[c] ","Cofactor and Prosthetic Group Biosynthesis"]
["R632","dihydrofolate reductase","H[c] + NADPH[c] + DHF[c]  -> NADP[c] + THF[c] ","Cofactor and Prosthetic Group Biosynthesis"]
["R634","methylenetetrahydrofolate reductase (ferredoxin)","2 H[c] + 5_10_MNTHF[c] + 2 R_FRDX[c]  -> 5MTHF[c] + 2 O_FRDX[c] ","Cofactor and Prosthetic Group Biosynthesis"]
["R636","thymidylate synthase","dUMP[c] + 5_10_MNTHF[c]  <=> dTMP[c] + DHF[c] ","Nucleotide Salvage Pathway"]
["R637","uridine nucleosidase","H2O[c] + URD[c]  -> D_RIB[c] + URA[c] ","Nucleotide Salvage Pathway"]
["R638","uridine phosphorylase","Pi[c] + URD[c]  -> R1P[c] + URA[c] ","Nucleotide Salvage Pathway"]
["R644","nucleoside-diphosphatase","H2O[c] + UDP[c]  -> Pi[c] + H[c] + UMP[c] ","Nucleotide Salvage Pathway"]
["R645","apyrase","CTP[c] + 2 H2O[c]  -> 2 Pi[c] + 2 H[c] + CMP[c] ","Nucleotide Salvage Pathway"]
["R647","nucleoside-diphosphatase","H2O[c] + CDP[c]  -> Pi[c] + H[c] + CMP[c] ","Nucleotide Salvage Pathway"]
["R649","formate hydrogenlyase","FOR[c]  -> 2 H[c] + CO2[c] ","Pyruvate Metabolism"]
["R650","phosphoserine aminotransferase","L_GLU[c] + 3POXPYR[c]  -> AKG[c] + PPTD_SER[c] ","Glycine and Serine Metabolism"]
["R651","3-phosphoserine phosphatase","H2O[c] + PPTD_SER[c]  -> L_SER[c] + Pi[c] ","Glycine and Serine Metabolism"]
["R653","coproporphyrinogen oxidase","2 H[c] + O2[c] + CPPPHYRGN[c]  -> 2 H2O[c] + 2 CO2[c] + PPPHYRGN[c] ","Cofactor and Prosthetic Group Biosynthesis"]
["R656","serine-glyoxylate transaminase","L_SER[c] + GLOXT[c]  -> L_GLY[c] + HY_PYR[c] ","Glycine and Serine Metabolism"]
["R662","glucose-1-phosphatase","H2O[c] + G1P[c]  -> Pi[c] + D_GLC[c] ","Glycolysis/Gluconeogenesis"]
["R663","phosphate acetyltransferase","Pi[c] + ACoA[c]  -> CoA[c] + ACPi[c] ","Pyruvate Metabolism"]
["R247","branched-chain alpha-keto acid dehydrogenase","3M_2OPENTN[c] + TPP[c]  -> CO2[c] + 2MHYBUT_ThPP[c] ","Valine, Leucine, and Isoleucine Metabolism"]
["R248","branched-chain alpha-keto acid dehydrogenase","4M_2OPENTN[c] + TPP[c]  -> CO2[c] + 3MHYBUT_ThPP[c] ","Valine, Leucine, and Isoleucine Metabolism"]
["R249","branched-chain alpha-keto acid dehydrogenase","2K3M_BUT[c] + TPP[c]  -> CO2[c] + 2MHYPROP_ThPP[c] ","Valine, Leucine, and Isoleucine Metabolism"]
["R250","branched-chain alpha-keto acid dehydrogenase","2MHYPROP_ThPP[c] + ENZN6_LPL[c]  -> TPP[c] + DHYLPL_MPROP_MPROP_DHLPL[c] ","Valine, Leucine, and Isoleucine Metabolism"]
["R251","branched-chain alpha-keto acid dehydrogenase","3MHYBUT_ThPP[c] + ENZN6_LPL[c]  -> TPP[c] + DHYLPL_MPROP_3MBUT_DHLPL[c] ","Valine, Leucine, and Isoleucine Metabolism"]
["R252","branched-chain alpha-keto acid dehydrogenase","2MHYBUT_ThPP[c] + ENZN6_LPL[c]  -> TPP[c] + DHYLPL_MPROP_2MBUT_DHLPL[c] ","Valine, Leucine, and Isoleucine Metabolism"]
["R710","gluconokinase","ATP[c] + GLCN[c]  -> ADP[c] + H[c] + GLCN6P[c] ","Pentose Phosphate Pathway"]
["R713","gluconolactonase","H2O[c] + GLC_LACN[c]  -> H[c] + GLCN[c] ","Pentose Phosphate Pathway"]