{"text_format":"3","workbook":"xls","n_sheets":1,"sheets":["Table 1"],"not_rendered":{"external_links":1,"defined_names":2},"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Table 1","index":0,"n_rows":138,"n_cols":13,"rows_kept":138,"merged":[[1,1,1,10],[2,1,3,1],[2,2,3,2],[2,3,3,3],[2,4,3,4],[2,5,3,5],[2,6,3,6],[2,7,2,10],[4,1,7,1],[4,2,7,2],[4,3,7,3],[4,4,7,4],[4,5,7,5],[4,6,7,6],[4,7,7,7],[4,8,7,8],[9,1,11,1],[9,2,11,2],[9,3,11,3],[9,4,11,4],[9,5,11,5],[9,6,11,6],[9,7,11,7],[9,8,11,8],[13,1,16,1],[13,2,16,2],[13,3,16,3],[13,4,16,4],[13,5,16,5],[13,6,16,6],[13,7,16,7],[13,8,16,8],[17,1,23,1],[17,2,23,2],[17,3,23,3],[17,4,23,4],[17,5,23,5],[17,6,23,6],[17,7,23,7],[17,8,23,8],[24,1,27,1],[24,2,27,2],[24,3,27,3],[24,4,27,4],[24,5,27,5],[24,6,27,6],[24,7,27,7],[24,8,27,8],[28,1,34,1],[28,2,34,2],[28,3,34,3],[28,4,34,4],[28,5,34,5],[28,6,34,6],[28,7,34,7],[28,8,34,8],[35,1,39,1],[35,2,39,2],[35,3,39,3],[35,4,39,4],[35,5,39,5],[35,6,39,6],[35,7,39,7],[35,8,39,8],[40,1,43,1],[40,2,43,2],[40,3,43,3],[40,4,43,4],[40,5,43,5],[40,6,43,6],[40,7,43,7],[40,8,43,8],[44,1,50,1],[44,2,50,2],[44,3,50,3],[44,4,50,4],[44,5,50,5],[44,6,50,6],[44,7,50,7],[44,8,50,8],[51,1,54,1],[51,2,54,2],[51,3,54,3],[51,4,54,4],[51,5,54,5],[51,6,54,6],[51,7,54,7],[51,8,54,8],[55,1,59,1],[55,2,59,2],[55,3,59,3],[55,4,59,4],[55,5,59,5],[55,6,59,6],[55,7,59,7],[55,8,59,8],[60,1,66,1],[60,2,66,2],[60,3,66,3],[60,4,66,4],[60,5,66,5],[60,6,66,6],[60,7,66,7],[60,8,66,8],[67,1,68,1],[67,2,68,2],[67,3,68,3],[67,4,68,4],[67,5,68,5],[67,6,68,6],[67,7,68,7],[67,8,68,8],[69,1,73,1],[69,2,73,2],[69,3,73,3],[69,4,73,4],[69,5,73,5],[69,6,73,6],[69,7,73,7],[69,8,73,8],[74,1,77,1],[74,2,77,2],[74,3,77,3],[74,4,77,4],[74,5,77,5],[74,6,77,6],[74,7,77,7],[74,8,77,8],[78,1,81,1],[78,2,81,2],[78,3,81,3],[78,4,81,4],[78,5,81,5],[78,6,81,6],[78,7,81,7],[78,8,81,8],[82,1,84,1],[82,2,84,2],[82,3,84,3],[82,4,84,4],[82,5,84,5],[82,6,84,6],[82,7,84,7],[82,8,84,8],[85,1,87,1],[85,2,87,2],[85,3,87,3],[85,4,87,4],[85,5,87,5],[85,6,87,6],[85,7,87,7],[85,8,87,8],[88,1,95,1],[88,2,95,2],[88,3,95,3],[88,4,95,4],[88,5,95,5],[88,6,95,6],[88,7,95,7],[88,8,95,8],[96,1,101,1],[96,2,101,2],[96,3,101,3],[96,4,101,4],[96,5,101,5],[96,6,101,6],[96,7,101,7],[96,8,101,8],[102,1,112,1],[102,2,112,2],[102,3,112,3],[102,4,112,4],[102,5,112,5],[102,6,112,6],[102,7,112,7],[102,8,112,8],[113,1,118,1],[113,2,118,2],[113,3,118,3],[113,4,118,4],[113,5,118,5],[113,6,118,6],[113,7,118,7],[113,8,118,8]],"flags":["formulas_cached_only"]}
[]
[null,"Table 1. Protein identification by MALDI-TOF/TOF-MS of tryptic peptides obtained from 2-DE spots of T98G and U87MG glioma cell lines"]
[null,"Spot\nID","U87MG / T98G expression ratio ± c.v.","T98G / U87MG expression ratio ± c.v.","Anova   (p value)","accession\nnumber\n(MW / pI)","Protein name","CID - MS/MS"]
[{"$nulls":7},"prot\nscore","% seq\ncov","unique peptides ","peptide sequence"]
[null,1,"1.34 ± 0.09","-",{"v":0.00534585,"d":"0.0053"},"UBIQ_HUMAN\n(8565 / 6.56)","Ubiquitin",302,61.8,1040.24,"34EGIPPDQQR42"]
[{"$nulls":9},1068.35,"64ESTLHLVLR72"]
[{"$nulls":9},1082.37,"55TLSDYNIQK63"]
[{"$nulls":9},1525.84,"30IQDKEGIPPDQQR42"]
[null,2,"1.92 ± 0.34","-",{"v":0.0421716,"d":"0.0422"},"S10AA_HUMAN (11317 / 6.62)","Protein S100-A10",58,10.3,{"v":1208.8,"d":"1208.80"},"38EFPGFLENQK47"]
[null,3,"1.95 ± 0.52","-",{"v":0.0303959,"d":"0.0304"},"SSBP_HUMAN (17259 / 9.59)","Single-stranded DNA-binding protein, mitochondrial",263,21.6,986.26,"96DVAYQYVK103"]
[{"$nulls":9},{"v":1150.3693,"d":"1150.37"},"114IDYGEYMDK122"]
[{"$nulls":9},{"v":1613.0028,"d":"1613.00"},"67SGDSEVYQLGDVSQK81"]
[null,4,"1.87 ± 0.40","-",{"v":0.0355681,"d":"0.0356"},"PTMS_HUMAN (11530 / 4.14)","Parathymosin ",67,10.8,1076.33,"5SVEAAAELSAK15"]
[null,5,"1.37 ± 0.18","-",{"v":0.0473803,"d":"0.0474"},"TEBP_HUMAN (18982 / 4.35)","Prostaglandin E synthase 3 ",230,18.8,922.18,"72SILCCLR78"]
[{"$nulls":9},1004.22,"80GESGQSWPR88"]
[{"$nulls":9},1132.42,"79KGESGQSWPR88"]
[{"$nulls":9},{"v":1446.7,"d":"1446.70"},"36LTFSCLGGSDNFK48"]
[null,6,"1.39 ± 0.19","-",{"v":0.0454309,"d":"0.0454"},"TPIS_HUMAN (26954 / 6.45)","Triosephosphate isomerase ",530,34.5,955.17,"7FVGGNWK14"]
[{"$nulls":9},1138.43,"60IAVAAQNCYK69"]
[{"$nulls":9},1235.51,"195SNVSDAVAQSTR206"]
[{"$nulls":9},1327.64,"207IIYGGSVTGATCK219"]
[{"$nulls":9},1467.77,"176TATPQQAQEVHEK188"]
[{"$nulls":9},1587.88,"86DCGATWVVLGHSER99"]
[{"$nulls":9},1639.98,"70VTNGAFTGEISPGMIK85"]
[null,7,"2.40 ± 0.52","-",{"v":0.0350508,"d":"0.0351"},"TPM4_HUMAN (28636 / 4.67)","Tropomyosin alpha-4 chain",253,17.7,1015.23,"45AEGDVAALNR54"]
[{"$nulls":9},{"v":1171.5,"d":"1171.50"},"133LVILEGELER142"]
[{"$nulls":9},1244.53,"56IQLVEEELDR65"]
[{"$nulls":9},1615.87,"14IQALQQQADEAEDR27"]
[null,8,"3.26 ± 0.47","-",{"v":0.00227179,"d":"0.0023"},"1433E_HUMAN (29345 / 4.63)","14-3-3 protein epsilon ",519,28.2,908.21,"43NLLSVAYK50"]
[{"$nulls":9},1206.57,"216DSTLIMQLLR225"]
[{"$nulls":9},{"v":1238.6,"d":"1238.60"},"107HLIPAANTGESK118"]
[{"$nulls":9},1257.58,"131YLAEFATGNDR141"]
[{"$nulls":9},1385.78,"131YLAEFATGNDRK142"]
[{"$nulls":9},1448.74,"30VAGMDVELTVEER42"]
[{"$nulls":9},1837.36,"154AASDIAMTELPPTHPIR170"]
[null,9,"1.57 ± 0.32","-",{"v":0.0457526,"d":"0.0458"},"LDHB_HUMAN (36923 / 5.71)","L-lactate dehydrogenase B chain ",372,16.8,914.25,"92IVVVTAGVR100"]
[{"$nulls":9},960.27,"300GLTSVINQK308"]
[{"$nulls":9},1177.46,"320SADTLWDIQK329"]
[{"$nulls":9},1249.48,"159VIGSGCNLDSAR170"]
[{"$nulls":9},1696.03,"8LIAPVAEEEATVPNNK23"]
[null,10,"2.19 ± 0.40","-",{"v":0.032951,"d":"0.0330"},"ANXA1_HUMAN (38942 / 6.57)","Annexin A1",381,13.3,909.05,"205ALYEAGER212"]
[{"$nulls":9},1214.35,"167DITSDTSGDFR177"]
[{"$nulls":9},1263.42,"114TPAQFDADELR124"]
[{"$nulls":9},1740.87,"189SEDFGVNEDLADSDAR204"]
[null,11,"3.01 ± 1.08","-",{"v":0.0188698,"d":"0.0189"},"RINI_HUMAN\n(51799 / 4.71)","Ribonuclease inhibitor",579,18.7,1150.41,"35LDDCGLTEAR44"]
[{"$nulls":9},1161.46,"196DSPCQLEALK205"]
[{"$nulls":9},1210.51,"54VNPALAELNLR64"]
[{"$nulls":9},1347.66,"342FLLELQISNNR352"]
[{"$nulls":9},1514.91,"360ELCQGLGQPGSVLR373"]
[{"$nulls":9},1531.76,"288ELSLAGNELGDEGAR302"]
[{"$nulls":9},1631.88,"174ELTVSNNDINEAGVR188"]
[null,12,"1.51  ±  0.17","-",{"v":0.0388425,"d":"0.0388"},"STMN1_HUMAN (17302 / 5.76)","Stathmin",219,29.5,1075.39,"44DLSLEEIQK52"]
[{"$nulls":9},1166.46,"86AIEENNNFSK95"]
[{"$nulls":9},1327.75,"30ESVPEFPLSPPK41"]
[{"$nulls":9},{"v":1389.8055,"d":"1389.81"},"15ASGQAFELILSPR27"]
[null,13,"2.99 ± 1.16","-",{"v":0.0193501,"d":"0.0194"},"PRDX6_HUMAN (25149 / 6.0)","Peroxiredoxin-6",354,22.8,{"v":907.1215,"d":"907.12"},"156NFDEILR162"]
[{"$nulls":9},{"v":916.1916,"d":"916.19"},"175VATPVDWK182"]
[{"$nulls":9},{"v":1192.5265,"d":"1192.53"},"145LSILYPATTGR155"]
[{"$nulls":9},{"v":1396.6561,"d":"1396.66"},"42DFTPVCTTELGR53"]
[{"$nulls":9},{"v":1583.752,"d":"1583.75"},"85DINAYNCEEPTEK97"]
[null,14,"1.39 ± 0.14","-",{"v":0.0311277,"d":"0.0311"},"PDIA3_HUMAN (57181 / 5.98)","Protein disulfide-isomerase A3",449,15.8,{"v":996.2786,"d":"996.28"},"131QAGPASVPLR140"]
[{"$nulls":9},{"v":1085.3309,"d":"1085.33"},"95YGVSGYPTLK104"]
[{"$nulls":9},{"v":1173.3962,"d":"1173.40"},"336FVMQEEFSR344"]
[{"$nulls":9},{"v":1192.4394,"d":"1192.44"},"63LAPEYEAAATR73"]
[{"$nulls":9},{"v":1237.3967,"d":"1237.40"},"108DGEEAGAYDGPR119"]
[{"$nulls":9},{"v":1369.6157,"d":"1369.62"},"367SEPIPESNDGPVK379"]
[{"$nulls":9},{"v":1681.9075,"d":"1681.91"},"434MDATANDVPSPYEVR448"]
[null,15,"-","2.33 ± 0.51",{"v":0.00989589,"d":"0.0099"},"MIF_HUMAN\n(12647 / 7.74)","Macrophage migration inhibitory factor ",79,17.4,{"v":1045.3659,"d":"1045.37"},"79LLCGLLAER87"]
[{"$nulls":9},{"v":1304.6941,"d":"1304.69"},"2PMFIVNTNVPR12"]
[null,16,"-","1.83 ± 0.28",{"v":0.00698418,"d":"0.0070"},"PPIA_HUMAN (18240 / 7.68)","Peptidyl-prolyl cis-trans isomerase A ",337,32.7,{"v":1056.1466,"d":"1056.15"},"20VSFELFADK28"]
[{"$nulls":9},{"v":1155.2447,"d":"1155.24"},"83FEDENFILK91"]
[{"$nulls":9},{"v":1248.3653,"d":"1248.37"},"155KITIADCGQLE165"]
[{"$nulls":9},{"v":1295.212,"d":"1295.21"},"134EGMNIVEAMER144"]
[{"$nulls":9},{"v":1615.5178,"d":"1615.52"},"56IIPGFMCQGGDFTR69"]
[null,17,"-","3.62 ± 0.65",{"v":0.00221932,"d":"0.0022"},"PRDX1_HUMAN (22338 / 8.27)","Peroxiredoxin-1",178,19.6,{"v":921.1797,"d":"921.18"},"129GLFIIDDK136"]
[{"$nulls":9},{"v":1108.451,"d":"1108.45"},"111TIAQDYGVLK120"]
[{"$nulls":9},{"v":1197.5564,"d":"1197.56"},"159LVQAFQFTDK168"]
[{"$nulls":9},{"v":1212.5887,"d":"1212.59"},"141QITVNDLPVGR151"]
[null,18,"-","2.30 ± 0.31",{"v":0.000877276,"d":"0.0009"},"EF1D_HUMAN (31236 / 4.9)","Elongation factor 1-delta",458,24.6,{"v":974.1317,"d":"974.13"},"233LVPVGYGIR241"]
[{"$nulls":9},{"v":1088.1607,"d":"1088.16"},"39QENGASVILR48"]
[{"$nulls":9},{"v":1359.4721,"d":"1359.47"},"84IASLEVENQSLR95"]
[{"$nulls":9},{"v":1528.5875,"d":"1528.59"},"25FYEQMNGPVAGASR38"]
[null,19,"-","2.10 ± 0.60",{"v":0.0214419,"d":"0.0214"},"HNRPC_HUMAN (33727 / 4.95)","Heterogeneous nuclear\nribonucleoproteins C1/C2 ",123,8.8,{"v":904.1142,"d":"904.11"},"136MYSYPAR142"]
[{"$nulls":9},{"v":944.2756,"d":"944.28"},"143VPPPPPIAR151"]
[{"$nulls":9},{"v":1330.7134,"d":"1330.71"},"51GFAFVQYVNER61"]
[null,20,"-","1.87 ± 0.47",{"v":0.0475847,"d":"0.0476"},"SET_HUMAN\n(33488 / 4.23)","Protein SET",290,11.7,{"v":1209.4482,"d":"1209.45"},"123VEVTEFEDIK132"]
[{"$nulls":9},{"v":1274.5708,"d":"1274.57"},"58LNEQASEEILK68"]
[{"$nulls":9},{"v":1447.6313,"d":"1447.63"},"155EFHLNESGDPSSK167"]
[null,21,"-","3.87 ± 1.03",{"v":0.0339785,"d":"0.0340"},"G6PD_HUMAN (59712 / 6.39)","Glucose-6-phosphate\n1-dehydrogenase",516,15.7,{"v":947.2008,"d":"947.20"},"10TQVCGILR17"]
[{"$nulls":9},{"v":1003.2781,"d":"1003.28"},"220IFGPIWNR227"]
[{"$nulls":9},{"v":1059.377,"d":"1059.38"},"167IIVEKPFGR175"]
[{"$nulls":9},{"v":1133.3945,"d":"1133.39"},"321GYLDDPTVPR330"]
[{"$nulls":9},{"v":1174.5071,"d":"1174.51"},"183LSNHISSLFR192"]
[{"$nulls":9},{"v":1192.4171,"d":"1192.42"},"499VGFQYEGTYK508"]
[{"$nulls":9},{"v":1233.5782,"d":"1233.58"},"206EMVQNLMVLR215"]
[{"$nulls":9},{"v":1809.0497,"d":"1809.05"},"105NSYVAGQYDDAASYQR120"]
[null,22,"-","3.20 ± 1.20",{"v":0.0491217,"d":"0.0491"},"TBA1A_HUMAN (50820 / 4.94)","Tubulin alpha-1A chain",390,14.9,{"v":904.0626,"d":"904.06"},"395FDLMYAK401"]
[{"$nulls":9},{"v":1016.298,"d":"1016.30"},"327DVNAAIATIK336"]
[{"$nulls":9},{"v":1086.3556,"d":"1086.36"},"113EIIDLVLDR121"]
[{"$nulls":9},{"v":1250.3559,"d":"1250.36"},"312YMACCLLYR320"]
[{"$nulls":9},{"v":1719.9831,"d":"1719.98"},"216NLDIERPTYTNLNR229"]
[{"$nulls":9},{"v":1826.2052,"d":"1826.21"},"353VGINYQPPTVVPGGDLAK310"]
[null,23,"-","3.73 ± 1.52",{"v":0.033767,"d":"0.0338"},"GRP78_HUMAN (72446 / 5.07) ","78 kDa glucose-regulated protein ",830,20.5,{"v":987.1006,"d":"987.10"},"533LTPEEIER540"]
[{"$nulls":9},{"v":1192.3561,"d":"1192.36"},"465VYEGERPLTK474"]
[{"$nulls":9},{"v":1212.3181,"d":"1212.32"},"377EFFNGKEPSR386"]
[{"$nulls":9},{"v":1218.3602,"d":"1218.36"},"186DAGTIAGLNVMR197"]
[{"$nulls":9},{"v":1229.3464,"d":"1229.35"},"50VEIIANDQGNR60"]
[{"$nulls":9},{"v":1317.4389,"d":"1317.44"},"563NELESYAYSLK573"]
[{"$nulls":9},{"v":1431.5289,"d":"1431.53"},"102TWNDPSVQQDIK113"]
[{"$nulls":9},{"v":1461.6379,"d":"1461.64"},"354SDIDEIVLVGGSTR367"]
[{"$nulls":9},{"v":1567.7005,"d":"1567.70"},"61ITPSYVAFTPEGER74"]
[{"$nulls":9},{"v":1678.7946,"d":"1678.79"},"82NQLTSNPENTVFDAK96"]
[{"$nulls":9},{"v":1838.014,"d":"1838.01"},"448SQIFSTASDNQPTVTIK464"]
[null,24,"-","1.69 ± 0.29",{"v":0.0223821,"d":"0.0224"},"GRP75_HUMAN (73965 / 5.87)","Stress-70 protein, mitochondrial ",545,11.5,{"v":1243.419,"d":"1243.42"},"207DAGQISGLNVLR218"]
[{"$nulls":9},1291.49,"395VQQTVQDLFGR405"]
[{"$nulls":9},{"v":1362.577,"d":"1362.58"},"349AQFEGIVTDLIR360"]
[{"$nulls":9},{"v":1451.5868,"d":"1451.59"},"86TTPSVVAFTADGER99"]
[{"$nulls":9},{"v":1463.671,"d":"1463.67"},"378SDIGEVILVGGMTR391"]
[{"$nulls":9},1695.86,"188NAVITVPAYFNDSQR202"]
{"$rows_empty":18}
[{"$nulls":12}," "]