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["Additional file 2: Table S3. All the differentially expressed proteins identified in perfusates from isolated rat livers metastasized by Walker-256 tumor cells. "]
["IPI","Protein name","Change direction","T value","Fold","SignalP","C-R1","C-R2","C-R3","C-R4","C-R5","M-R1","M-R2","M-R3","M-R4","M-R5"]
["IPI00195798","Prep RPOP","Elevated",3.90018148795608,"∞",null,0,0,0,0,0,7,5,8,4,3]
["IPI00212697","Napsa napsin A aspartic peptidase","Elevated",4.17733064576877,"∞","yes",0,0,0,0,0,2,3,2,2,4]
["IPI00368874","LOC299458 LOC299458 protein","Elevated",4.3261557299346,"∞","yes",0,0,0,0,0,8,8,5,5,3]
["IPI00554077","Ighg Immunoglobulin heavy chain","Elevated",10.2694367833866,"∞","yes",0,0,0,0,0,9,6,8,10,7]
["IPI00198685","Pak1 Serine/threonine-protein kinase PAK 1","Elevated",6.93030690361981,"∞",null,0,0,0,0,0,2,3,2,2,2]
["IPI00201436","Mat1a S-adenosylmethionine synthetase isoform type-1","Elevated",6.4946863548696,"∞",null,0,0,0,0,0,7,7,4,6,8]
["IPI00371235","Apob48r apolipoprotein B48 receptor","Elevated",4.29273091838918,"∞",null,0,0,0,0,0,2,2,1,3,3]
["IPI00209291","Mbc2 Extended-synaptotagmin-1","Elevated",3.8406790219160998,"∞",null,0,0,0,0,0,4,4,2,2,5]
["IPI00363763","RGD1311558 Isoform 1 of Shootin-1","Elevated",4.90112351352095,25.90364505951149,null,0,1,0,0,0,3,2,6,6,4]
["IPI00366953","Bzw1 Basic leucine zipper and W2 domain-containing protein 1","Elevated",4.78091732086142,20.525768961276444,null,0,1,0,0,0,4,3,2,6,2]
["IPI00193648","G3bp1 similar to Ras-GTPase-activating protein binding protein 1","Elevated",5.1247125292562,18.585507285029294,null,3,0,1,0,0,9,19,11,13,7]
["IPI00421720","Rpl21 60S ribosomal protein L21","Elevated",6.47622014838571,15.829546448472696,null,0,1,0,0,0,4,2,2,3,2]
["IPI00363828","Actr3 Actin-related protein 3","Elevated",5.08771547295592,11.839766551513994,null,2,1,0,0,0,7,6,4,3,8]
["IPI00339148","Hspd1 60 kDa heat shock protein, mitochondrial","Elevated",4.31641949904667,11.719059410628786,null,0,2,0,1,0,6,6,3,11,4]
["IPI00191995","Epb4.1l2 89 kDa protein","Elevated",4.92859834242217,11.247706176485746,null,0,0,0,1,0,2,3,1,2,2]
["IPI00361346","IgG-2a LOC367586 protein","Elevated",21.1124134950629,11.204891111198473,"yes",2,0,5,4,10,43,43,38,42,40]
["IPI00231046","Psma4 Proteasome subunit alpha type-4","Elevated",5.23821078651844,11.071757954784552,null,3,0,1,0,0,8,9,9,5,4]
["IPI00199867","Emilin1 elastin microfibril interfacer 1","Elevated",5.88464853264138,9.222337176186818,"yes",4,0,2,0,0,8,8,7,8,13]
["IPI00766018","Eif3s2;LOC682390 Eukaryotic translation initiation factor 3 subunit I","Elevated",5.86395422532756,8.417124807544882,null,0,0,0,0,3,5,6,4,4,4]
["IPI00358691","Eps15 Epidermal growth factor receptor pathway substrate 15","Elevated",7.16081725232348,8.309173209615821,null,2,0,4,0,0,11,7,6,10,7]
["IPI00230954","Dync1i2 Isoform 2B/2A/2C of Cytoplasmic dynein 1 intermediate chain 2","Elevated",6.46208744864936,8.253138445721177,null,0,0,0,6,0,10,7,8,9,10]
["IPI00207217","Echs1 Enoyl-CoA hydratase, mitochondrial","Elevated",11.0635044761972,7.338633266773051,null,3,0,3,3,4,18,16,12,17,19]
["IPI00213015","Dctn2 Dynactin subunit 2","Elevated",5.11566067448432,7.057456535226533,null,2,0,1,0,0,3,2,4,5,3]
["IPI00560977","Caprin1 Caprin-1","Elevated",6.09813732003099,6.029689024516654,null,0,2,2,1,2,4,9,7,9,7]
["IPI00206020","Lrrc59 Leucine-rich repeat-containing protein 59","Elevated",4.85387102322094,5.887167741884418,null,0,0,0,0,8,9,9,8,9,8]
["IPI00231783","Ldhb L-lactate dehydrogenase B chain","Elevated",5.26859822267653,5.614339177316189,null,0,2,3,0,3,8,9,8,4,9]
["IPI00393333","Atic Bifunctional purine biosynthesis protein PURH","Elevated",5.29717165764999,5.588686283992649,null,0,2,0,3,7,17,12,12,12,7]
["IPI00212731","Ctsd Cathepsin D","Elevated",7.94419880810262,5.570914555206517,"yes",0,4,7,1,3,15,15,13,18,10]
["IPI00764535","Arpc2 Actin-related protein 2/3 complex subunit 2","Elevated",3.58588581240985,5.488719061081129,null,3,0,0,0,0,2,2,2,4,3]
["IPI00365657","Vasp vasodilator-stimulated phosphoprotein","Elevated",3.97561376278606,5.102127916454178,null,2,0,0,0,5,4,6,6,6,9]
["IPI00370486","- Ig lambda-2 chain C region","Elevated",7.52453850039123,4.959874453756796,null,3,4,2,5,4,14,20,15,16,11]
["IPI00209258","Spna2 Spectrin alpha chain, brain","Elevated",5.36855254073481,4.6636647098739115,null,0,5,6,0,5,12,14,9,19,10]
["IPI00210158","Psmc4 26S protease regulatory subunit 6B","Elevated",3.63561974967192,4.480739380729844,null,0,0,3,0,6,6,9,5,11,5]
["IPI00200661","Fasn Fatty acid synthase","Elevated",5.86445476454137,4.338024048851538,null,0,3,5,2,0,7,8,8,6,7]
["IPI00209082","Actn1 Alpha-actinin-1","Elevated",12.3287328143375,4.165336010824364,null,10,14,18,14,10,44,45,45,44,53]
["IPI00210147","Sec31a Isoform 1/2 of Protein transport protein Sec31A","Elevated",3.71536309006612,4.078333700328567,null,0,0,0,3,4,5,5,5,8,3]
["IPI00198369","Snx1 Sorting nexin-1","Elevated",4.20573733550182,3.967004892937796,null,6,0,7,0,0,8,8,7,12,7]
["IPI00373246","Anp32e Acidic leucine-rich nuclear phosphoprotein 32 family member E","Elevated",3.35814136961238,3.7248599901341346,null,7,10,3,0,4,24,15,6,20,10]
["IPI00365423","Ppp2r1a Protein phosphatase 2 (Formerly 2A), regulatory subunit A (PR 65), alpha isoform","Elevated",6.58104779432409,3.549892335205094,null,4,2,6,4,3,13,7,13,13,11]
["IPI00211133","Cdc37 Hsp90 co-chaperone Cdc37","Elevated",3.40405757240555,3.5259852109891043,null,4,0,1,1,0,2,3,4,4,4]
["IPI00230837","Ywhab Isoform Long/short of 14-3-3 protein beta/alpha","Elevated",7.04947083475203,3.457403179053067,null,9,19,22,14,15,59,45,42,57,30]
["IPI00361890","Upp1 Uridine phosphorylase 1","Elevated",6.78263631123874,3.3797453071068135,null,10,13,22,19,20,61,42,42,65,35]
["IPI00210264","Gsto1 Glutathione transferase omega-1","Elevated",3.95689506700289,3.3673930160926684,null,0,12,6,2,1,16,11,11,13,8]
["IPI00197568","Gdi2 Rab GDP dissociation inhibitor beta","Elevated",4.89148945282829,3.329386637361301,null,4,7,4,2,3,10,10,10,9,16]
["IPI00555187","Cap1 Adenylyl cyclase-associated protein 1","Elevated",8.81783714583846,3.2612317640184587,null,16,13,28,24,23,56,44,61,67,61]
["IPI00200757","Fn1 Isoform 1/2 of Fibronectin","Elevated",10.4004837910737,3.2060808247495305,"yes",9,11,13,9,7,33,27,25,24,23]
["IPI00193500","H2afy Isoform 2/1 of Core histone macro-H2A.1","Elevated",3.66455356079833,3.0809903561825536,null,0,9,10,5,7,16,16,24,16,9]
["IPI00212014","Vcp Transitional endoplasmic reticulum ATPase","Elevated",6.8038682149041,3.0686793419095806,null,2,10,13,9,17,24,24,27,33,27]
["IPI00202687","Zbp1 Z-DNA-binding protein 1","Elevated",3.94009716928347,3.0402369818020674,null,0,5,4,1,4,8,10,7,5,6]
["IPI00231194","Ddah1 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1","Elevated",4.41323127331452,3.0151223648428833,null,0,7,13,7,11,26,21,21,20,11]
["IPI00189061","Marcksl1 MARCKS-related protein","Elevated",5.61120216407885,2.9374338269389213,null,5,10,16,9,0,22,20,18,21,17]
["IPI00195372","Eef1a1 Elongation factor 1-alpha 1","Elevated",4.43951861557826,2.8472493112285657,null,23,24,35,13,38,55,69,74,88,36]
["IPI00370011","Eif1 Eukaryotic translation initiation factor 1","Elevated",4.62761947451811,2.8303291681895844,null,0,2,3,1,3,5,4,3,5,5]
["IPI00369102","RGD1564921 similar to peptidylprolyl isomerase H","Elevated",3.92603817509517,2.77609009896046,null,3,0,6,3,5,8,10,8,5,9]
["IPI00188622","Tgfbi similar to transforming growth factor, beta induced","Elevated",3.52493254892506,2.7011638143701653,"yes",2,2,9,4,10,17,10,16,11,9]
["IPI00365769","Iqgap1 IQ motif containing GTPase activating protein 1","Elevated",4.16505517212708,2.604909246421278,null,6,6,5,7,9,24,13,11,14,12]
["IPI00231734","Aldoa Fructose-bisphosphate aldolase A","Elevated",7.15806318077698,2.5807178587832484,null,8,8,4,10,7,14,15,14,20,18]
["IPI00368347","Uba1 Ubiquitin-activating enzyme E1","Elevated",6.25573123343666,2.5448336983347395,null,6,4,4,8,10,15,11,14,15,15]
["IPI00882501","Ncl Nucleolin","Elevated",4.12700697430303,2.5373409572270265,null,5,3,3,3,0,4,7,6,6,6]
["IPI00190606","Myl1 Myosin light chain 1, skeletal muscle isoform","Decreased",4.28301996029168,"∞",null,4,5,2,3,2,0,0,0,0,0]
["IPI00203630","Grb2 Isoform 1/2 of Growth factor receptor-bound protein 2","Decreased",4.956431716518722,"∞",null,6,3,3,3,3,0,0,0,0,0]
["IPI00203829","Atox1 Copper transport protein ATOX1","Decreased",4.008047469262174,"∞",null,10,8,5,5,3,0,0,0,0,0]
["IPI00204359","B2m Beta-2-microglobulin","Decreased",7.125045469402983,"∞","yes",7,10,11,8,11,0,0,0,0,0]
["IPI00210824","Serpina6 Corticosteroid-binding globulin","Decreased",7.073419521085952,"∞","yes",4,3,5,3,3,0,0,0,0,0]
["IPI00212319","App Isoform APP770 of Amyloid beta A4 protein (Fragment)/App Isoform APP695 of Amyloid beta A4 protein (Fragment)","Decreased",5.275485625993909,"∞","yes",4,6,3,5,3,0,0,0,0,0]
["IPI00324027","Spink3 Serine protease inhibitor Kazal-type 3","Decreased",3.375131092696959,"∞","yes",4,8,4,4,2,0,0,0,0,0]
["IPI00327630","Dync1h1 Cytoplasmic dynein 1 heavy chain 1","Decreased",5.817864854133969,"∞",null,8,8,14,9,11,0,0,0,0,0]
["IPI00327770","Mbl2 Mannose-binding protein C","Decreased",5.690224321082477,"∞","yes",2,3,3,4,3,0,0,0,0,0]
["IPI00370073","Krt17 Keratin, type I cytoskeletal 17","Decreased",9.538176547837324,"∞",null,4,4,5,3,4,0,0,0,0,0]
["IPI00231107","Ptms Parathymosin","Decreased",7.997363443224438,19.538017123551725,null,22,21,31,32,33,0,0,2,2,2]
["IPI00870082","Cd163 CD163 molecule","Decreased",4.960185477773766,16.46342697434961,null,9,14,5,6,7,0,0,0,0,2]
["IPI00210091","Serpina3m similar to Serine protease inhibitor A3M precursor","Decreased",4.122690048433416,15.194685224546959,"yes",2,6,2,3,4,1,0,0,0,0]
["IPI00231328","Cxcl2 Macrophage inflammatory protein 2","Decreased",5.207995572553235,11.882268421642793,"yes",9,7,14,8,5,1,0,0,0,2]
["IPI00324272","Apoa4 Apolipoprotein A-IV","Decreased",22.674063827713574,8.654295467194205,"yes",22,21,20,21,18,2,0,2,3,3]
["IPI00207487","Fgf21 Fibroblast growth factor 21","Decreased",7.295341991722024,5.296468482962286,"yes",14,23,26,21,21,4,4,4,5,0]
["IPI00764009","LOC682869 similar to Golgi phosphoprotein 2 (Golgi membrane protein GP73) isoform 2","Decreased",4.42919159274435,5.06735630334875,"yes",9,4,8,10,5,0,2,0,2,2]
["IPI00231772","Ecm1 Extracellular matrix protein 1","Decreased",3.6521228327769255,4.8144162140487605,"yes",5,18,16,19,9,5,3,2,2,0]
["IPI00198466","Amy1 Alpha-amylase","Decreased",6.518912548064623,3.893066997633409,"yes",18,28,24,18,14,7,4,4,3,4]
["IPI00324380","Ttr Transthyretin","Decreased",3.949165778268791,3.6630549439548816,"yes",15,16,31,33,33,6,8,4,6,6]
["IPI00191423","Leap2 Leap2 protein","Decreased",3.722532495521421,3.4857631363622836,"yes",7,6,7,7,6,3,5,0,0,0]
["IPI00202416","Igfals Insulin-like growth factor-binding protein complex acid labile chain","Decreased",5.500711482142738,3.11712603202171,"yes",10,13,9,7,10,0,4,3,3,3]
["IPI00231643","Sod1 Superoxide dismutase [Cu-Zn]","Decreased",5.077176440257884,3.098948861431182,null,361,491,551,418,579,178,165,189,127,0]
["IPI00371043","Armet Protein ARMET","Decreased",4.352578088156809,3.04142019176338,"yes",9,8,10,6,7,4,4,0,0,3]
["IPI00188225","Crp C-reactive protein","Decreased",4.247154338696503,2.9067879975888817,"yes",56,45,29,28,22,8,8,12,10,13]
["IPI00199670","Serpinf1 Alpha-2 antiplasmin","Decreased",5.402074798000373,2.8795990468082455,"yes",13,19,17,15,9,3,6,4,3,5]
["IPI00196656","Srprb Ba1-667","Decreased",3.922094054267833,2.631006543586753,"yes",1191,1009,1000,901,887,569,0,478,0,523]
["\"SignalP\": the protein was predicted by the software of SignalP 3.0 as classically secreted."]
["\"M-R1-5\": spectral counts identified in each MS analysis for the model perfusates."]
["\"C-R1-5\": spectral counts identified in each MS analysis for the control perfusates."]