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{"sheet":"Table 1 - Suppl Information","index":0,"n_rows":617,"n_cols":32,"rows_kept":617,"merged":[[0,0,0,27],[1,0,1,31],[3,0,4,0],[3,1,4,1],[3,2,4,2],[3,3,4,3],[3,4,4,4],[3,6,4,6],[3,7,4,7],[3,8,4,8],[3,9,4,9],[3,10,4,10],[3,11,4,11],[3,14,4,14],[3,15,4,15],[3,16,4,16],[3,17,4,17],[3,18,4,18],[3,19,4,19],[3,20,4,20],[3,21,4,21],[3,22,4,22],[3,23,4,23],[3,25,4,25],[3,26,4,26],[3,27,4,27],[3,28,4,28],[3,29,4,29],[3,30,4,30],[3,31,4,31],[428,0,428,31],[429,0,430,0],[429,1,430,1],[429,2,430,2],[429,3,430,3],[429,4,430,4],[429,6,430,6],[429,7,430,7],[429,8,430,8],[429,9,430,9],[429,10,430,10],[429,11,430,11],[429,14,430,14],[429,15,430,15],[429,16,430,16],[429,17,430,17],[429,18,430,18],[429,19,430,19],[429,20,430,20],[429,21,430,21],[429,22,430,22],[429,23,430,23],[429,25,430,25],[429,26,430,26],[429,27,430,27],[429,28,430,28],[429,29,430,29],[429,30,430,30],[429,31,430,31],[581,0,581,7],[582,0,582,7],[583,0,584,7],[585,0,585,7],[586,0,586,7],[587,0,589,7],[590,0,590,7],[591,0,594,7],[595,0,596,7],[597,0,597,7],[598,0,600,7],[601,0,604,7],[605,0,605,7],[606,0,606,7],[607,0,612,7],[613,0,613,7],[614,0,615,7],[616,0,616,7]],"flags":["formulas_cached_only"]}
["Supplemental Table. Yersinia pestis KIM6+ membrane proteome analysis"]
["Part I. Protein annotations, descriptions, differential gel display and MS data pertaining to proteins separated in 2D gels "]
["a)","b)","c)","d)","d)","e)","f)","g)","h)","i)","j)","k)","l)","m)","n)","o)","p)","q)","r)","r)","s)","t)","t)","u)","v)","w)","x)","y)","y)","z)","z)","aa)"]
["Spot no.","Locus tag","Gene name","Acc. no. gi|","Acc. no.","MPC","Category","Protein name and description","XN CYP","XN hs-MBR","XN hpH-MBR","XN usb-MBR","EM","EIM","Vs CYP","Vs hs-MBR","Vs hpH-MBR","Vs usb-MBR","MS score","Sequence coverage of tryptic peptides ","MS  score","pI","Mr","P-SO RTb  ","BO ","TMHMM","Lipo-P","Signal-P ","Signal-P (HMM)","Main functional role (CMR)","Sub-role (CMR)","(Putative) protein motifs and functions"]
[{"$nulls":24},"MP"]
[]
[209,"y0031","malK",22123952,"NP_667375","Y","i-M","maltose/maltodextrin ABC transporter ATP-binding protein","N.A.","N.A.","10303554 (39%)","2889712 (62%)","+",null,"+","+",8185332,2475352,512,"2-369 (L) incl. 2-11; 12-263 (M) incl. 12-20 ",50,5.97,40985,"IM",null,0,null,"N",null,"Transport and binding proteins","Carbohydrates, organic alcohols, and acids","Component of multimeric inner membrane ABC transporter for maltose"]
[300,"y0036","-",22123957,"NP_667380",null,"i-M","hemolysin-coregulated protein (HCP)","N.A.","N.A.","1252647 (120%)","N.A.","+",null,"+",null,676962,null,142,"2-172 (L) incl. 2-12 ",null,5.46,19202,"U",null,0,null,"N",null,"Unknown function","General","Putative type VI secretion system protein, HCP-like"]
[274,"y0038","-",22123959,"NP_667382",null,"i-M","hypothetical protein y0038 (putative type VI secretion system subunit)","N.A.","N.A.","4684131 (48%)","N.A.","+",{"$nulls":3},1204014,null,232,"77-443 (M); 2-489 (L) incl. 2-29; 30-443 (L)",null,5.46,56211,"U",null,0,null,"N",null,"Hypothetical proteins","Conserved","Putative component of secretion system involved in export of cytotoxins"]
[null,"y0108","(yicH)",22124028,"NP_667451",null,"i-M","hypothetical protein y0108 (putative LPS biogenesis protein) ",{"$nulls":4},"+",{"$nulls":4},"+",112,"273-490 (L)",69,5.81,62714,"OM",null,1,null,"Y"," 32-33","Unknown function","General","AsmA family protein possibly involved in outer membrane biogenesis with cell-cell adhesion domain"]
[47,"y0118","(lppC)",22124038,"NP_667461",null,"i-M","glycosylase ","N.A.","N.A.","N.A.","1941978 (13%)","+",{"$nulls":3},"+",702290,415,"95-689; 111-689; 95-689; 111-673 (L); 95-681 (M)",null,5,74211,"U",null,0,"(LP)","N",null,"Cell envelope","Other","Putative lipoprotein and transglycosylase "]
[46,"y0123","(yraP)",22124043,"NP_667466"," ","i-M","hypothetical protein y0123 (putative phospholipid-binding lipoprotein) ","N.A.","N.A.","N.A.","1784471 (123%)","+",null,"+","+","+",11053661,462,"55-206 (L)",1442,9.46,21966,"P",null,1,"OM-LP","Y  ","38-39","Cellular processes","Pathogenesis","Protein with putative domain for phospholipid attachment "]
[225,"y0136","(yhcB)",22124056,"NP_667479","Y","i-M","cytochrome d ubiquinol oxidase subunit III","N.A.","N.A.","N.A.","5352541 (49%)","+",null,"+","+","+",1178778,402,"30-134 (M); 30-134 (L); 30-112 (L)",190,5.64,15476,"U",null,1,null,"N",null,"Cell envelope","Other","Putative cytochrome D ubiquinol oxidase subunit III"]
[284,"y0142  "," (yrbB)",22124062,"NP_667485",null,"i-M","hypothetical protein y0142  ","N.A.","N.A.","1483072 (34%)","N.A.","+",null,"+",null,1628374,null,60,"42-49 (L); 50-80 (L)",null,4.85,11343,"U",null,0,null,"N",null,"Unknown function","General","Similar to yrbB gene product of E. coli,unknown function"]
[226,"y0146","(yrbF)",22124066,"NP_667489"," ","i-M","putative ABC transporter ATP-binding protein YrbF  ",{"$nulls":4},"+",null,"+","+","+",1102622,194,"25-272 (L); 39-272 (L); 3-272 (L) incl. 3-15 ",null,5.3,29949,"MSL",null,0,null,"N",null,"Transport and binding proteins","Unknown substrate","Transport system involved in resistance to organic solvents"]
[60,"y0153","lptB",22124073,"NP_667496"," ","i-M","putative ABC transporter ATP-binding protein YhbG (LptB)","N.A.","N.A.","806378 (58%)","741698 (92%)","+",null,"+","+",1275374,576886,259,"2-231 (L); 2-241 (L) incl. 2-8 and 17-27 (L); 1-241 (M) incl. 1-8 ",null,6.02,26967,"C",null,0,null,"N",null,"Transport and binding proteins","Unknown substrate","Putative ABC-type transport system involved in LPS biosynthesis and interacting with LptA"]
[2,"y0184","tcbA",22124104,"NP_667527",null,"i-M","toxin complex protein  ","N.A.","N.A.","N.A.","861641 (26%)","+",{"$nulls":4},256846,972,"131-1151 (M); 2-1176 (L) incl. 2-9 and 15-25 ",null,5.54,137158,"OM",null,0,null,"N",null,"Cellular processes","Toxin production and resistance","Toxin with putative extracellular functions (P. luminescence)"]
[3,"y0185","tcaC1",22124105,"NP_667528",null,"i-M","toxin complex protein ","N.A.","N.A.","N.A.","1072139 (10%)","+",{"$nulls":4},187953,130,"346-829 (L)",null,5.17,171442,"OM",null,0,null,"N",null,"Cellular processes","Toxin production and resistance","Toxin with putative extracellular functions (P. luminescence)"]
[61,"y0202","mreB",22124122,"NP_667545","Y","i-M","regulator of ftsI and penicillin-binding protein 3","N.A.","N.A.","1289531 (88%)","960879 (88%)","+",null,"+",null,779880,1950450,366,"28-301 (M); 28-347 (L); 28-301 (M); 28-347 (L); 28-347 (L) ",221,5.18,37049,"C",null,0,null,"N",null,"Cellular processes","Cell division","Peripheral membrane protein involved in cell division and morphogenesis; complex with MurG"]
[238,"y0209","accC",22124129,"NP_667552",null,"i-M","acetyl-CoA carboxylase biotin carboxylase subunit ","N.A.","N.A.","463034 (49%)","261741 (57%)","+",null,"+","+","+",207808,285,"28-423 (L); 151-423 (L); 126-449 (L)",143,6.38,49962,"C",null,0,null,"N",null,"Fatty acid and phospholipid metabolism","Biosynthesis","Membrane-associated acetyl-CoA carboxylase complex  "]
[null,"y0329","(ytfR)",22124246,"NP_667669"," ","i-M","ATP-binding component of ATP transport system ",{"$nulls":4},"+",{"$nulls":3},"+",null,117,"340-438 (L)",null,5.93,54564,"MSL",null,0,null,"N",null,"Transport and binding proteins","Carbohydrates, organic alcohols, and acids","ABC transporter on unknown substrate specificity"]
[null,"y0363","wzzE",22124278,"NP_667701",null,"i-M","transport protein (lipopolysaccharide biosynthesis)",{"$nulls":4},"+",{"$nulls":4},"+",173,"12-310 (L) incl. 12-28 (L); 12-326 (L)",773,5.72,39850,"IM",null,2,null,"N",null,"Cell envelope","Other","Chain-length determinant factor for involved in lipopolysaccharide biosynthesis"]
[null,"y0378","hemY",22124293,"NP_667716",null,"i-M","putative protoheme IX biogenesis protein",{"$nulls":4},"+",null,null,"+","+","+",143,"144-384 (L); 110-260 (L)",73,8.71,45951,"C",null,2,null,"Y ","24-25","Unknown function","General","Enzyme probably involved in late-step protoheme IX biosynthesis "]
[48,"y0379","hemX",22124294,"NP_667717","Y","i-M","uroporphyrinogen III methylase","N.A.","226562 (28%)","1396791 (19%)","1991137 (39%)","+",{"v":26.661433196683365,"d":"26.6614"},null,null,"+",1999984,511,"90-327 (M); 90-357 (L)",190,4.76,41948,"U",null,1,null,"N",null,"Biosynthesis of cofactors, prosthetic groups, and carriers","Heme, porphyrin, and cobalamin","Heme / porphyrin and vitamin B12 cofactor biosynthesis "]
[null,"y0393","corA",22124308,"NP_667731",null,"i-M","magnesium and cobalt permease (cation transport)",{"$nulls":4},"+",{"$nulls":4},"+",81,"224-233 (L); 224-233 (L)",null,4.72,38488,"C",null,2,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","Cobalt and magnesium ion transport acorss the IM"]
[null,"y0407","-",22124322,"NP_667745",null,"i-M","hypothetical protein y0407 (putative inner membrane lipoprotein)",{"$nulls":4},"+",{"$nulls":4},"+",226,"40-110 (L); 40-110 (L)",134,5.8,18869,"U",null,0,"IM-LP","Y ","25-26","Unknown function","General","Putative inner membrane lipoprotein"]
[266,"y0410","zntA",22124325,"NP_667748",null,"i-M","zinc, lead, cadmium, and mercury transporting ATPase ","N.A.","N.A.","N.A.","323855 (61%)","+",{"$nulls":3},"+",3874700,84,"452-642 (L)",null,5.7,84427,"IM",null,6,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","Transmembrane cation ion transport, confers resistance to bivalent metals Pb, Zn, Cd "]
[270,"y0416","ftsY",22124331,"NP_667754",null,"i-M","cell division membrane protein ",{"$nulls":4},"+",{"$nulls":4},1090782,441,"18-445 (L) incl. 18-31 ",null,4.45,60150,"IM",null,0,null,"N",null,"Cellular processes","Cell division","Signal recognition particle-docking protein"]
[null,"y0418","ftsX",22124333,"NP_667756",null,"i-M","cell division protein FtsX",{"$nulls":4},"+",{"$nulls":4},"+",62,"160-170 (L)",null,7.82,34883,"IM",null,4,null,"N",null,"Protein fate","Protein and peptide secretion and trafficking","FtsE/X complex is involved in cell division, particularly the stability of the septal ring assembly at low osmotic strength "]
[131,"y0442","metE",22124357,"NP_667780","Y","i-M","5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase ","N.A.","N.A.","1628232 (55%)","741693 (72%)","+",null,752672,null,402772,689254,395,"27-757 (M); 27-763 (L); ",235,5.44,86555,"C",null,0,null,"N",null,"Amino acid biosynthesis","Aspartate family","Methionine biosynthesis"]
[35,"y0448","(rumC)",22124363,"NP_667786",null,"i-M","alpha helix chain (putative DNA recombination protein)","N.A.","N.A.","N.A.","245664 (57%)","+",{"$nulls":4},158734,681,"75-501 (L); 75-501 (L)",null,5.81,57455,"IM",null,1,null,"N",null,"DNA metabolism","DNA replication, recombination, and repair","Putative DNA recombination protein limiting inversions of genes"]
[" ","y0539","hmuV",22124453,"NP_667876 "," ","i-M","ATP-binding protein of ABC transporter ",{"$nulls":4},"+",{"$nulls":4},535330,105,"73-111 (L)",null,8.31,25806,"U",null,0,null,"N",null,"Transport and binding proteins","Amino acids, peptides and amines","Component of multimeric inner membrane ABC transporter for hemin"]
[62,"y0555","terZ",22124469,"NP_667892",null,"i-M","putative tellurium resistance protein  ","N.A.","N.A.","563087 (41%)","350325 (20%)","+",null,516914,null,614026,2313048,452,"18-208 (L) incl. 18-25; 18-208 (L) incl. 18-25 (L); 33-208 (M)",118,6.1,23001,"C",null,0,null,"N",null,"Cellular processes","Adaptations to atypical conditions","Possibly involved in stress response, Colicin and tellurite resistance"]
[227,"y0632","hflX",22124545,"NP_667968",null,"i-M","putative GTPase HflX (protease subunit of lambda cII repressor) ","N.A.","N.A.","N.A.","395721 (17%)","+",{"$nulls":4},367916,401,"63-405 (L); 72-371 (M)",null,6,48172,"C",null,0,null,"N",null,"Protein fate","Degradation of proteins, peptides, and glycopeptides","GTPase part of protease of lambda cII repressor complex"]
[49,"y0633","hflK",22124547,"NP_667970","Y","i-M","FtsH protease regulator HflK","N.A.","N.A.","N.A.","126609 (57%)","+",null,null,"+","+",187103,377,"140-358 (L)",415,7.79,45258,"U",null,1,null,"N",null,"Protein fate","Degradation of proteins, peptides, and glycopeptides","High  frequency of lysogenization K protein subunit"]
[50,"y0634","hflC",22124548,"NP_667971",null,"i-M","FtsH protease regulator HflC","N.A.","N.A.","N.A.","207874 (82%)","+",{"$nulls":3},"+",303285,393,"103-275 (L)",560,7.85,37414,"U",null,1,null,"Y ","25-26","Protein fate","Degradation of proteins, peptides, and glycopeptides","High  frequency of lysogenization K protein subunit"]
[51,"y0661","(ytfN)",22124574,"NP_667997",null,"i-M","hypothetical protein y0661  ","N.A.","N.A.","N.A.","211143 (27%)","+",{"$nulls":4},175599,505,"231-1223 (L)",136,7.14,140006,"U",2,1,null,"Y ","28-29","Unknown function","General","Putative exported protein with unknown functions"]
[153,"y0664","fbp",22124578,"NP_668001","Y","i-M","fructose-1,6-bisphosphatase  ","N.A.","N.A.","1689151 (56%)","619186 (67%)","+",null,"+",null,null,376966,590,"38-372 (L); 38-372 (M)",321,6.03,41455,"U",null,2,null,"N",null,"Energy metabolism","Glycolysis/gluconeogenesis","Membrane-associated fructose 1,6 bisphosphatase "]
[119,"y0678","dacB",22124592,"NP_668015",null,"i-M","D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)",{"$nulls":4},"+",null,null,3512070,null,null,373,"48-482 (L)",null,9.06,52429,"U",null,0,"(LP)","Y ","26-27","Cell envelope","Biosynthesis and degradation of murein sacculus and peptidoglycan","Penicillin-binding protein 4 "]
[228,"y0682","hflB",22124596,"NP_668019",null,"i-M","ATP-dependent inner membrane metalloprotease ","N.A.","N.A.","277491 (34%)","N.A.","+",null,null,1674851,380800,"+",173,"80-553 (L); 202-354 (L); 547-598 (L)",974,5.76,71208,"IM",null,2,null,"N",null,"Cellular processes","Cell division","ATP-dependent zinc metalloprotease involved in membrane fusion during cell division "]
[null,"y0685","secG",22124599,"NP_668022",null,"i-M","preprotein translocase subunit SecG ",{"$nulls":4},"+",{"$nulls":4},"+",68,"81-111 (L); 93-111 (L)",181,5.05,11623,"IM",null,2,null,"N",null,"Protein fate","Protein and peptide secretion and trafficking","Subunit SecG of Sec YEG translocon complex required for protein export from cytoplasm"]
[null,"y0695","(nlpI)",22124609,"NP_668032",null,"i-M","lipoprotein NlpI",{"$nulls":4},"+",{"$nulls":4},"+",68,"47-272 (L)",null,4.72,33834,"U ",null,0,"OM-LP","N",null,"Unclassified","Role category not yet assigned","Lipoprotein NlpI, homolog in pathogenic E. coli LH82 strain involved in adherence and invasion of epithelial cells  "]
[null,"y0702","(acrA2)",22124616,"NP_668039",null,"i-M","acridine efflux pump  (drug transport)",{"$nulls":4},"+",null,null,"+",null,"+",81,"309-324 (L); 52-324 (L)",63,5.71,41031,"IM",null,0,null,"Y","26-27","Transport and binding proteins","Other","Multidrug efflux protein also involved in membrane fusion  "]
[null,"y0704","(ibeB)",22124618,"NP_668041",null,"i-M","outer membrane efflux pump protein ",{"$nulls":4},"+",{"$nulls":4},"+",146,"75-468 (L)",null,5.84,49727,"OM ",null,0,"OM-LP","Y ","21-22","Transport and binding proteins","Unknown substrate","Outer membrane channel protein, putative copper/silver efflux system (E. coli)"]
[288,"y0735","dppD",22124649,"NP_668072"," ","i-M","ATP-binding component of dipeptide transport system",{"$nulls":4},"+",null,null,"+","+",null,206,"43-299 (L)",null,6.18,33380,"IM",null,0,null,"N",null,"Transport and binding proteins","Unknown substrate; Amino acids, peptides and amines","Component of multimeric inner membrane ABC transporter for dipeptides"]
[230,"y0795","mrcB",22124708,"NP_668131",null,"i-M","penicillin-binding protein 1b",{"$nulls":4},"+",{"$nulls":4},571295,149,"108-693 (L); 90-693 (L); 152-772 (L)",111,9.43,85641,"MSL",null,1,null,"Y ","33-34","Cell envelope","Biosynthesis and degradation of murein sacculus and peptidoglycan","Carboxypeptidase /  transglycosylase with a TM, a second IM association site and large periplasmic domain (E. coli)"]
[null,"y0827","ftsB",22124738,"NP_668161",null,"i-M","cell divison protein FtsB  ",{"$nulls":10},205,"24-93 (L)",260,5.35,11862,"U",null,0,null,"N",null,"Unclassified","Role category not yet assigned","Colocalizes to the septal region of the dividing cell"]
[203,"y0833","nlpD",22124744,"NP_668167",null,"i-M","predicted outer membrane lipoprotein NlpD",{"$nulls":4},"+",null,"+","+","+","+",238,"222-312 (L)",112,9.52,34917,"U",null,0,null,"N",null,"Cell envelope","Other","Lipoprotein, protease with LysM domain for bacterial cell wall degradation "]
[null,"y0835","mutS",22124746,"NP_668169",null,"i-M","DNA mismatch repair protein (MutS-family ATPase)",{"$nulls":4},"+",{"$nulls":3},"+","+",216,"142-846 (M); 47-620 (L); 7-620 (L) incl. 7-19",null,5.69,95039,"U",null,0,null,"N",null,"DNA metabolism","DNA replication, recombination, and repair","Repair ATPase, MutS family"]
[52,"y0911","(yfiO)",22124819,"NP_668242",null,"i-M","predicted lipoprotein ","N.A.","N.A.","N.A.","471315 (50%)","+",{"$nulls":3},"+",1039424,465,"25-223 (M); 25-233 (L)",108,7.71,27542,"U ",null,0,"OM-LP","Y ","25-26","Cell envelope","Other","YfiO stabilizes YaeT complex essential for outer membrane assembly"]
[286,"y0923","emrR",22124831,"NP_668254",null,"i-M","transcriptional repressor MprA ","N.A.","N.A.","1065165 (87%)","N.A.","+",{"$nulls":3},1199676,null,114,"79-106 (L)",57,8.63,21092,"C",null,0,null,"N",null,"Mobile and extrachromosomal element functions","Plasmid functions","DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux"]
[212,"y0951","nqrA",22124858,"NP_668281","Y","i-M","Na(+)-translocating NADH-quinone reductase subunit A  ","N.A.","N.A.","1359203 (119%)","1236836 (80%)","+",null," ","+",2713074,null,440,"60-443 (L); 68-443 (M) ",62,6.42,49989,"U",null,0,null,"N",null,"Energy metabolism","Electron transport","Moves Na(+) ions from the cytoplasm to the periplasm"]
[null,"y0992","yajC",22124899,"NP_668322",null,"i-M","preprotein translocase subunit YajC  ",{"$nulls":4},"+",{"$nulls":4},"+",104,"75-94 (L); 75-94 (L); 82-94 (L)",293,9.3,14693,"U",null,2,null,"N",null,"Protein fate","Protein and peptide secretion and trafficking","Subunit YidC of preprotein translocase in inner membrane"]
[null,"y0993","secD",22124900,"NP_668323",null,"i-M","preprotein translocase subunit SecD  ",{"$nulls":4},"+",{"$nulls":4},"+",126,"146-155 (L); 283-297 (L); 146-297 (L)",582,8.8,66861,"IM",null,6,null,"Y ","31-32","Protein fate","Protein and peptide secretion and trafficking","Subunit SecD of Sec protein export complex,  important for release of protein from translocon complex SecYEG"]
[null,"y1021","cyoA",22124928,"NP_668351",null,"i-M","cytochrome o ubiquinol oxidase subunit II  ",{"$nulls":4},"+",{"$nulls":4},"+",130,"204-318 (L); 204-254 (L); 242-254 (L); 242-254 (L); 242-254 (L)",589,8.75,35083,"IM ",null,3,"OM-LP","Y ","25-26","Energy metabolism","Anaerobic, Electron transport","Oxidative phosphorylation, major component of respiratory complex during vegetative growth"]
[null,"y1024","(yajG) ",22124931,"NP_668354",null,"i-M","hypothetical protein y1024 (putative lipoprotein)",{"$nulls":4},"+",{"$nulls":4},"+",138,"127-161 (L)",290,8.66,20866,"U ",null,0,"OM-LP","Y ","25-26","Unknown function","General","Lipoprotein with polymerase and protease domains "]
[53,"y1031","(ppiD)",22124938,"NP_668361","Y","i-M","peptidyl-prolyl cis-trans isomerase (rotamase D) ","N.A.","1492988 (81%)","3475613 (32%)","1483690 (31%)","+",{"v":4.228419724054544,"d":"4.2284"},"+","+","+",635303,777,"53-566 (M); 45-628 (L); 45-628; 1-628 (L) incl. 1-6 and 7-15",541,4.95,69849,"U",null,1,null,"N",null,"Unclassified","Role category not yet assigned","Parvulin-like peptidyl/prolyl isomerase likely involved in folding of OMPs"]
[null,"y1049","acrB",22124956,"NP_668379",null,"i-M","acridine efflux pump (multidrug transport)",{"$nulls":4},"+",{"$nulls":4},"+",142,"270-849 (L); 270-309 (L)",1222,5.8,113603,"IM",null,11,null,"Y ","27-28","Transport and binding proteins","Other","Multidrug efflux pump protein in complex with AcrB and TolC"]
[36,"y1050","acrA",22124957,"NP_668380","Y","i-M","acridine efflux pump (multidrug resistance efflux transporter)","N.A.","N.A.","N.A.","3377429 (13%)","+",null,"+","+","+",3245426,584,"29-394 (L); 29-393 (M); 29-393 (L); 29-393 (M)",595,6.1,41921,"IM",null,0,"IM-LP","Y ","25-26","Cell envelope","Other","Multidrug efflux pump protein in complex with AcrA and TolC"]
[null,"y1170","tatE",22125073,"NP_668496",null,"i-M","twin arginine translocase protein A  ",{"$nulls":4},"+",{"$nulls":4},"+",97,"65-83 (L); 27-58 (L)",432,8.01,8880,"U",null,1,null,"N",null,"Unknown function","General","Component of transmembrane sectretion pathway Tat"]
[198,"y1175","dacA",22125078,"NP_668501",null,"i-M","D-alanyl-D-alanine carboxypeptidase fraction A ",{"$nulls":4},"+",{"$nulls":3},883462,7555962,1445,"56-392 (L); 111-379 (M)",105,8.65,44118,"IM",null,0,null,"Y ","27-28","Cell envelope","Biosynthesis and degradation of murein sacculus and peptidoglycan","Putative penicillin-binding protein 5 , anchored to inner membrane on periplasmic side via C-terminal domain"]
[257,"y1176","rlpA",22125079,"NP_668502",null,"i-M","rare lipoprotein A ",{"$nulls":4},"+",{"$nulls":4},"+",135,"47-360 (L)",104,5.76,38052,"U ",null,0,"OM-LP","N",null,"Cell envelope","Other","Lipoprotein possibly involved in sporulation and cell division "]
[258,"y1183","rlpB",22125086,"NP_668509",null,"i-M","LPS assembly lipoprotein RplB","N.A.","N.A.","N.A.","452548 (96%)","+",null,"+",null,"+",1081108,278,"26-157 (L)",206,6.43,22613,"U",null,1,"OM-LP","Y ","27-28","Cell envelope","Other","Lipoprotein B forms complex with Imp essential for LPS biosynthesis and assembly in outer membrane "]
[289,"y1186","gltL",22125089,"NP_668512"," ","i-M","ATP-binding protein of glutamate/aspartate transport system ","N.A.","N.A.","1817006 (29%)","470442 (61%)","+",null,null,"+",1324612,"+",77,"47-229 (M); 2-229 (L) incl. 2-6 ",null,6.23,26914,"C",null,0,null,"N",null,"Transport and binding proteins","Amino acids, peptides and amines","Component of multimeric inner membrane ABC transporter for glutamate/aspartate"]
[null,"y1203","nagE",22125106,"NP_668529",null,"i-M","N-acetylglucosamine-specific PTS system enzyme IIABC ",{"$nulls":4},"+",{"$nulls":4},"+",119,"411-471 (L); 552-576 (L)",145,5.97,71877,"IM",null,9,null,"N",null,"Transport and binding proteins","Amino acids, peptides and amines","Sugar phosphotransferase system for N-acetylglucosamine, glucose, mannose, permease domain"]
[67,"y1221","proV",22125123,"NP_668546","Y","i-M","ATP-binding component of high affinity Gly / betaine / Pro transporter ","N.A.","512033 (N/A)","8303069 (117%)","1755016 (208%)","+",{"v":20.67635339092198,"d":"20.6764"},null,562359,11992910,4760766,301,"52-438 (L); 52-438 (L); 52-369 (M);  52-433 (L); 52-355 (M)",null,5.88,48729,"C",null,0,null,"N",null,"Transport and binding proteins","Amino acids, peptides and amines","ATPase involved in small molecule transport"]
[null,"y1247","-",22125147,"NP_668570",null,"i-M","voltage-gated potassium channel ","N.A.","3667857 (13%)","6266506 (8%)","N.A.",null,{"v":1.27143624344717,"d":"1.2714"},{"$nulls":4},110,"333-345 (L) ",null,7.66,43298,"IM",null,7,null,"N",null,"Fatty acid and phospholipid metabolism","Biosynthesis","Voltage-gate ion channel (VIC family of transporters) with S-adenosyl-L-homocysteine hydrolase domain"]
[null,"y1296","lepB",22125196,"NP_668619",null,"i-M","signal peptidase I (leader peptidase)",{"$nulls":4},"+",{"$nulls":3},"+","+",108,"35-46 (L); 35-46 (L); 35-46 (L)",null,6.9,36811,"IM",null,2,null,"N",null,"Protein fate","Protein and peptide secretion and trafficking","Cleavage of N-terminal hydrophobic signal peptides prior to protein export"]
[81,"y1314","-",22125214,"NP_668637",null,"i-M","hypothetical protein y1314; putative alpha helix protein","N.A.","N.A.","N.A.","490539 (22%)","+",{"$nulls":3},"+",443737,161,"59-312 (L)",56,8.54,39453,"U",null,0,null,"N",null,"Transcription","Transcription factors","Putative alpha helix protein with STAT protein interaction domain "]
[null,"y1321","hmpA",22125220,"NP_668643",null,"i-M","nitric oxide dioxygenase",{"$nulls":4},"+",{"$nulls":4},"+",128,"1-54 (L) incl. 1-11 (L); 41-235 (L)",null,5.94,45016,"U",null,0,null,"N",null,"Energy metabolism","Electron transport","Ferrisiderophore reductase activity, response protein to nitrosative stress"]
[231,"y1334","(nifS)",22125233,"NP_668656",null,"i-M","cysteine desulfurase ","N.A.","N.A.","N.A.","921814 (16%)","+",{"$nulls":3},"+",1233324,344,"8-359 (M) incl. 8-23; 8-359 (L); 8-359 (L)) incl. 8-23 ",null,5.94,45457,"U",null,0,null,"N",null,"Biosynthesis of cofactors, prosthetic groups, and carriers","Other","catalyses removal of sulfur from cysteine"]
[264,"y1346","yapA",22125245,"NP_668668",null,"i-M","autotransporter",{"$nulls":4},"+",null,"+",null,null,"+",310,"1222-1437 (L)",null,4.85,149543,"MSL",2,1,null,"Y ","29-30","Unclassified","Role category not yet assigned","Self-secreting putative virulence factor with extracellular pertactin adherence domain (B. pertussis)"]
[null,"y1351","(pilF)",22125250,"NP_668673",null,"i-M","fimbrial biogenesis protein ",{"$nulls":4},"+",{"$nulls":4},"+",78,"59-79 (L)",null,8.82,27710,"U",null,0,"(LP)","Y ","28-29","Cellular processes","Chemotaxis and motility","Putative pilus assembly protein PilF  "]
[141,"y1353","ispG",22125252,"NP_668675",null,"i-M","4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase ","N.A.","N.A.","N.A.","164678 (34%)","+",null,"+",null,"+",224578,273,"20-365 (L) incl. 20-37; 38-365 (L)",74,6.56,41058,"C",null,0,null,"N",null,"Biosynthesis of cofactors, prosthetic groups, and carriers","Other","Isopentenyldiphosphate biosynthesis "]
[54,"y1355","(yfgM) ",22125254,"NP_668677","Y","i-M","hypothetical protein y1355 ","N.A.","1974082 (38%)","871586 (N/A)","2556032 (41%)","+",{"v":3.5806128832847195,"d":"3.5806"},1723772,1739927,1095582,3355962,1030,"1-169 (M) incl. 1-15; 1-211 (L) incl. 1-15 ",175,5.49,22627,"U",null,1,null,"N",null,"Unknown function","General","Homolog involved in host colonization in S. enterica; transmembrane domain"]
[55,"y1356","(yfgL)",22125255,"NP_668678",null,"i-M","outer membrane protein assembly complex subunit YfgL","N.A.","N.A.","N.A.","562158 (N/A)","+",null,"+",null,"+",2096976,348,"38-393 (M); 38-393; 38-378 (L)",54,4.99,42122,"U ",null,0,"OM-LP","Y ","25-26","Central intermediary metabolism","Other","Outer membrane lipoprotein part of the YaeT/YfiO/YfgL assembly complex "]
[null,"y1376","-",22125275,"NP_668698",null,"i-M","hypothetical protein y1376  ",{"$nulls":4},"+",null,null,"+",null,"+",184,"77-140 (L)",null,9.54,18811,"U",null,0,null,"Y ","25-26","Energy metabolism","Sugars","Putative exported protein with Ivy domain (inhibitor of vertebrate lysozyme) "]
[70,"y1401","pstB1",22125299,"NP_668722"," ","i-M","phosphate-specific ABC transporter component ","N.A.","N.A.","N.A.","388282 (22%)","+",{"$nulls":3},"+",467295,99,"51-268 (L); 260-268 (M)",null,6.18,30904,"C",null,0,null,"N",null,"Transport and binding proteins","Anions","Phosphate ABC-type transport system with ATPase activity "]
[null,"y1412","(yfgC)",22125310,"NP_668733",null,"i-M","hypothetical protein y1412 (putative metalloprotease)",{"$nulls":4},"+",{"$nulls":3},"+","+",257,"120-504 (L); 120-504 (L); 120-494 (L)",null,9.09,57637,"IM",null,0,null,"Y ","59-60","Cell envelope","Other","Putative Zinc-dependent protease (M48 family) with tetratricopeptide domain "]
[268,"y1432","potA",22125330,"NP_668753"," ","i-M","spermidine/putrescine transport ATP-binding protein ","N.A.","N.A.","5689784 (23%)","689919 (75%)","+",{"$nulls":3},1688826,null,458,"30-345 (L); 37-338 (M)",null,5.91,40541,"C",null,0,null,"N",null,"Transport and binding proteins","Amino acids, peptides and amines","Component of multimeric inner membrane ABC transporter for polyamines"]
[201,"y1469","cysA",22125366,"NP_668789"," ","i-M","sulfate/thiosulfate ABC transporter subunit ","N.A.","N.A.","1434845 (77%)","N.A.","+",null,"+","+",2361816,"+",336,"51-372 (L);  68-355 (M)",null,7.98,41741,"C",null,0,null,"N",null,"Transport and binding proteins","Anions","Involved in sulfate import and possibly chromate resistance  "]
[37,"y1491","zipA",22125388,"NP_668811",null,"i-M","cell division protein ZipA ","N.A.","N.A.","1496283 (32%)","2587215 (10%)","+",null,"+","+",737770,1623637,167,"46-341 (L)   ",154,5.51,37647,"IM",null,1,null,"N",null,"Cellular processes","Cell division","Cell division protein interacting with FtsZ and required for septal ring formation"]
[281,"y1524","yfuC",22125421,"NP_668844"," ","i-M","ATP-binding protein of iron ABC transporter  ","N.A.","N.A.","2582165 (N/A)","N.A.","+",{"$nulls":3},"+","+",63,"115-126 (L)",null,6.64,37846,"C",null,0,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","Possibly involved in spermidine / putrescine transport in addition to iron III "]
[null,"y1527","mltB",22125424,"NP_668847",null,"i-M","murein hydrolase B",{"$nulls":4},"+",{"$nulls":4},"+",68,"307-319 (L)",null,8.75,41342,"IM ","1*",0,"OM-LP","Y ","33-34","Cell envelope","Biosynthesis and degradation of murein sacculus and peptidoglycan","Lytic transglycosylase involved in peptidoglycan metabolism "]
[null,"y1576","vacJ",22125471,"NP_668894",null,"i-M","surface lipoprotein VacJ",{"$nulls":4},"+",{"$nulls":4},"+",63,"200-220 (L)",78,4.9,28538,"IM ",null,0,"OM-LP","Y ","26-27","Cell envelope","Other","Cell surface lipoprotein possibly involved in intercellular spreading (S. flexneri)"]
[null,"y1580","fadJ",22125475,"NP_668845",null,"i-M","multifunctional fatty acid oxidation complex subunit alpha",{"$nulls":4},"+",null,"+",null,"+","+",101,"199-749 (L); 217-749 (L); 291-749 (L)",313,9.38,84129,"U",null,0,null,"N",null,"Fatty acid and phospholipid metabolism","Degradation","Enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase, lipid metabolism "]
[" ","y1603","dedD",22125498,"NP_668921","Y","i-M","putative lipoprotein y1603",{"$nulls":4},"+",{"$nulls":3},1911046,null,78,"192-206 (L)",61,7.8,25637,"U",null,1,null,"N",null,"Unknown function","General","Putative membrane protein  "]
[296,"y1673","glnQ",22125568,"NP_668850"," ","i-M","glutamine ABC transporter ATP-binding protein","N.A.","N.A.","1328583 (72%)","N.A.","+",{"$nulls":3},589086,null,154,"130-231 (L)",null,6.46,26604,"C",null,0,null,"N",null,"Transport and binding proteins","Amino acids, peptides and amines","Component of multimeric inner membrane ABC transporter for glutamine"]
[null,"y1767","ptsG",22125661,"NP_668851",null,"i-M","glucose-specific PTS system component  IIBC ",{"$nulls":4},"+",{"$nulls":4},"+",114,"240-424 (L); 68-135 (L)",null,8.58,51064,"IM",null,9,null,"N",null,"Transport and binding proteins","Carbohydrates, organic alcohols, and acids","Sugar phosphotransferase system for N-acetylglucosamine, glucose, mannose, permease domain"]
[297,"y1786","lolD",22125680,"NP_668852"," ","i-M","lipoprotein ABC transporter ATP-binding subunit  ","N.A.","N.A.","1066607 (26%)","N.A.","+",{"$nulls":3},685328,"+",143,"73-82 (L)",53,6.56,25740,"IM",null,0,null,"N",null,"Transport and binding proteins","Unknown substrate","Part of transporter complex lolCDE involved in the translocation of mature OM-directed lipoproteins"]
[210,"y1795","-",22125689,"NP_669112",null,"i-M","hypothetical protein y1795 (putative lipoprotein)",{"$nulls":4},"+",{"$nulls":3},"+",3992364,481,"41-204 (M); 41-204 (L)",null,7.79,22869,"OM ",5,0,"OM-LP","Y ","21-22","Cell envelope","Other","Putative lipoprotein with similarity to opacity family porin proteins (Neisseria ssp.)"]
[null,"y1852","(rssA1)",22125745,"NP_669168",null,"i-M","hypothetical protein y1852 (putative patatin-like phospholipase)",{"$nulls":4},"+",{"$nulls":4},"+",53,"376-386 (L)",59,6.84,45705,"IM ",null,1,"OM-LP","Y ","25-26","Cell envelope","Other","Lipoprotein with putative phospholipase function"]
[null,"y1863","(yebT)",22125756,"NP_669179",null,"i-M","hypothetical protein y1863 ",{"$nulls":4},"+",{"$nulls":4},"+",86,"98-750 (L)",null,6.92,95966,"OM",null,1," ","N",null,"Hypothetical proteins","Conserved","MCE-related proteins (necessary for colonization and survival in macrophages)"]
[197,"y1867","prc",22125760,"NP_669183",null,"i-M","carboxy-terminal protease for penicillin-binding protein 3","N.A.","N.A.","324659 (56%)","N.A.","+",null,"+",null,429960,1077986,183,"44-706 (L)",null,7.6,79094,"U",null,1,null,"Y ","38-39","Protein fate","Degradation of proteins, peptides, and glycopeptides","Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of PBP3"]
[null,"y1877","(ampD2)",22125770,"NP_669193",null,"i-M","regulator (putative N-acetylmuramoyl-L-alanine amidase)",{"$nulls":4},"+",{"$nulls":3},"+","+",202,"23-244 (L)",null,8.49,31328,"C ",null,0,"OM-LP","Y ","20-21","Cellular processes","Toxin production and resistance","Homologous to N-Acetyl-N-muramoyl-L-alanine amidase (S. tenterica); C-terminal peptidoglycan anchor motif "]
[null,"y1878","(ydjN)",22125771,"NP_668853",null,"i-M","symporter (predicted sodium and dicarboxylate symporter)",{"$nulls":4},"+",{"$nulls":4},"+",189,"250-465 (L); 250-465 (L); 250-465 (L) ",570,9.32,49044,"IM",null,9,null,"Y ","28-29","Transport and binding proteins","Carbohydrates, organic alcohols, and acids","Putative symporter for dicarboxylates and sodium"]
[272,"y1896","yfeB",22125789,"NP_668854","Y","i-M","ATP-binding protein for iron and manganese ABC transporter ","N.A.","N.A.","5437294 (48%)","1320785 (77%)","+",null,null,"B193B",2081218,"+",174,"68-282 (M); 56-282 (M); 56-282 (L); 68-282 (L)",null,6.2,32490,"MSL",null,0,null,"N",null,"Transport and binding proteins","Unknown substrate; Amino acids, peptides and amines; Cations and iron carrying compounds","Component of multimeric inner membrane ABC transporter for iron/manganese"]
[125,"y1919","(wcaG9)",22125812,"NP_669235",null,"i-M","bifunctional UDP glucuronic acid decarboxylase/formyl transferase ","N.A.","N.A.","N.A.","261217 (49%)","+",null,290376,307192,"+","+",529,"138-619 M); 138-667 (L)",null,5.88,75330,"U",null,0,null,"N",null,"Cell envelope","Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides","Protein with formyltransferase and nucleoside-diphosphate sugar epimerase domains; LPS biosynthesis"]
[232,"y1926","lplA",22125819,"NP_668855",null,"i-M","lipoate-protein ligase A ","N.A.","N.A.","3551838 (83%)","198992 (73%)","+",{"$nulls":4},547092,114,"147-310 (L)",null,5.87,38312,"C",null,0,null,"N",null,"Cell envelope","Other","Protein lipoate macromolecule biosynthesis"]
[233,"y1928","aroH",22125820,"NP_668856",null,"i-M","3-deoxy-7-phosphoheptulonate synthase  ",{"$nulls":4},"+",{"$nulls":3},"+",738252,454,"12-320 (L) incl. 12-24; 12-253 (L); 12-253 (M) incl. 12-24 ",null,5.35,38628,"C",null,0,null,"N",null,"Amino acid biosynthesis","Aromatic amino acid family","Tryptophan biosynthesis , possibly involved in inner core lipid II biosynthesis of LPS"]
[33,"y1962","slyB1",22125854,"NP_669277",null,"i-M","outer membrane protein  ","N.A.","N.A.","N.A.","381474 (37%)","+",{"$nulls":3},"+",595215,271,"109-155 (L); 85-155; 85-155; 85-155 ",1894,9.51,15414,"U ",null,0,"OM-LP","Y ","22-23","Unclassified","Role category not yet assigned","Putative outer membrane lipoprotein, possibly involved in haemolysis with SlyA "]
[234,"y1988","tyrR",22125880,"NP_668858",null,"i-M","tyrosine-binding and DNA-binding transcriptional dual regulator ","N.A.","N.A.","N.A.","425921 (42%)","+",null,null,"+",null,339802,306,"114-270 (L); 99-545 (L)",null,5.71,62791,"C",null,0,null,"N",null,"Transport and binding proteins","Amino acids, peptides and amines","Regulator for aromatic acids biosynthesis and metabolism, ATPase domain"]
[null,"y2003","hslJ",22125895,"NP_669318",null,"i-M","heat-inducible protein HslJ  ",{"$nulls":4},"+",{"$nulls":4},"+",150,"88-146 (L)",null,6.27,16464,"U ",null,0,"OM-LP","Y ","24-25","Cellular processes","Adaptations to atypical conditions","Adaptive response to heat shock  "]
[null,"y2010","acpD",22125902,"NP_669325",null,"i-M","azoreductase (acyl carrier protein phosphodiesterase)",{"$nulls":4},"+",null,null,"+",null,"+",133,"115-201 (L); 107-158 (M)",null,5.02,21586,"U",null,0,null,"N ","(21-22)","Fatty acid and phospholipid metabolism","Biosynthesis","Catalyzes the hydrolytic cleavage of the 4'-phosphopantetheine residue from ACP"]
[null,"y2037","tonB",22125929,"NP_668859"," ","i-M","energy transducer; part of TonB/ExbB/ExbD complex",{"$nulls":4},"+",{"$nulls":3},"+","+",71,"152-168 (L); 138-168 (L); 138-168 (L)",326,6.07,27485,"P",null,1,null,"Y ","29-30","Transport and binding proteins","Cations and iron carrying compounds","TonB complex protein, required for energy-dependent transport of molecules across OM via OM receptors "]
[11,"y2044","(ompW)",22125935,"NP_669358",null,"i-M","outer membrane protein W","N.A.","N.A.","1780695 (90%)","327395 (72%)","+",{"$nulls":3},"+",752887,141,"35-153 (L)",null,5.34,23667,"OM",4,0,null,"Y ","26-27","Cell envelope","Other","Possibly involved in paraquat efflux (S. typhimurium)"]
[null,"y2045","(osmY1)",22125936,"NP_669359",null,"i-M","hypothetical protein y2045 (putative phospholipid-binding lipoprotein)",{"$nulls":4},"+",{"$nulls":4},"+",111,"69-83 (L)",61,9.64,11127,"P ",null,0,"OM-LP","Y ","23-24","Cellular processes","Other","Hyperosmotically inducible protein with putative domain for phospholipid attachment  "]
[38,"y2047","trpA",22125938,"NP_668860",null,"i-M","tryptophan synthase subunit alpha ","N.A.","N.A.","N.A.","483978 (23%)","+",{"$nulls":4},430655,133,"180-221 (L)",null,5.84,31625,"IM",null,0,null,"N",null,"Amino acid biosynthesis","Aromatic amino acid family","Tryptophan biosynthesis from chorismate"]
[207,"y2104","(ydgA)",22125993,"NP_669416","Y","i-M","hypothetical protein y2104 (putative phospholipid-binding lipoprotein) ","N.A.","N.A.","936633 (23%)","1353845 (85%)","+",null,229552,"+",532940,1471452,1015,"58-492 (L); 71-492 (M)",405,5.26,58864,"U",null,1,null,"Y ","45-46","Unknown function","General","Putative periplasmic / exported protein with unknown functions"]
[" ","y2134","pntB",22126022,"NP_668861",null,"i-M","pyridine nucleotide transhydrogenase, beta subunit ",{"$nulls":4},"+",{"$nulls":4},"+",134,"293-441 (L); 351-452 (L)",455,5.39,49076,"IM",null,9,null,"Y ","23-24","Energy metabolism","Electron transport","Membrane-bound proton pump, reversible transfer of hydride between NAD / NADH"]
[null,"y2135","pntA",22126023,"NP_668862",null,"i-M","NAD(P) transhydrogenase, subunit alpha ",{"$nulls":4},"+",{"$nulls":3},"+","+",235,"109-151 (L); 109-201 (L); 72-151 (L)",542,5.16,54407,"IM",null,5,null,"N",null,"Energy metabolism","Electron transport","Membrane-bound proton pump, reversible transfer of hydride between NAD / NADH"]
[null,"y2160","sppA",22126048,"NP_668863",null,"i-M","protease IV (signal peptide peptidase)  ",{"$nulls":4},"+",{"$nulls":4},"+",102,"370-494 (L); 370-384 (L); 370-384 (L)",136,6.69,67106,"IM",null,1,null,"N",null,"Protein fate","Degradation of proteins, peptides, and glycopeptides","Protease of S49 peptidase family involved in maturation of exported proteins"]
[252,"y2233","minD",22126119,"NP_669542",null,"i-M","cell division inhibitor MinD","N.A.","N.A.","2112505 (18%)","968124 (25%)","+",null,412719,"+",1474620,642850,370,"34-245 (M); 45-245 (M); 4-245 (L) incl. 4-11; 4-245 (L) incl. 4-11",84,5.06,29772,"C",null,0,null,"N",null,"Cellular processes","Cell division","Membrane-associated ATPase activating MinC; involved in septum formation / cell division "]
[73,"y2234","minE",22126120,"NP_668864",null,"i-M","cell division topological specificity factor MinE ","N.A.","N.A.","1204823 (23%)","411785 (41%)","+",{"$nulls":3},989660,402073,148,"22-89 (L); 31-89 (L)",null,5.34,10383,"C",null,0,null,"N",null,"Cellular processes","Cell division","Septum-formation topological specificity factor involved in cell division"]
[null,"y2237","(slp)",22126123,"NP_669546",null,"i-M","outer membrane lipoprotein ",{"$nulls":4},"+",{"$nulls":4},"+",92,"60-138 (L)",55,9.47,21996,"U",null,1,"OM-LP","Y ","42-43","Cell envelope","Other","Starvation-inducible outer membrane lipoprotein of unknown function, Slp family "]
[74,"y2263","cutC",22126149,"NP_668865",null,"i-M","copper homeostasis protein CutC","N.A.","N.A.","N.A.","463814 (54%)","+",{"$nulls":3},"+",356058,352,"78-211 (L); 36-268 (L)",null,5.81,29787,"C",null,0,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","Uncharacterized protein involved in copper resistance "]
[84,"y2270","(yceM)",22126156,"NP_669579",null,"i-M","virulence factor ","N.A.","N.A.","N.A.","782040 (88%)","+",{"$nulls":4},453534,196,"108-472 (L); 108-366 (L)",584,6.29,60159,"U",null,0,null,"N",null,"Unknown function","General","Putative oxidoreductase and virulence factor (E. coli)"]
[259,"y2292","lolb",22126177,"NP_669600",null,"i-M","outer membrane lipoprotein LolB ",{"$nulls":4},"+",{"$nulls":4},1087542,139,"134-217; 62-217 (L)",52,9.16,26380,"U",null,0,"OM-LP","N",null,"Protein fate","Protein and peptide secretion and trafficking","Involved in assembly of lipoproteins in outer membrane "]
[279,"y2315","-",22126199,"NP_668866",null,"i-M","hypothetical protein y2315",{"$nulls":4},"+",null,"+",null,null,948534,452,"33-310 (M); 33-310 (L)",null,6.06,35255,"U",null,0,null,"N",null,"Hypothetical proteins","Conserved","Local sequence similarity to coat protein readthrough of oat golden stripe virus"]
[275,"y2364","(phnL4)",22126248,"NP_668867"," ","i-M","ABC transporter ATP-binding protein","N.A.","N.A.","2167743 (N/A)","N.A.","+",{"$nulls":3},1584958,null,96,"2-158 (L) incl. 2-21; 2-143 (L) incl. 2-21 ",null,5.82,26653,"IM",null,0,null,"N",null,"Transport and binding proteins","Unknown substrate","SalX domain, putative antimicrobial (macrolide) transport protein important for defense"]
[null,"y2396","ybtQ",22126280,"NP_668868"," ","i-M","permease/ATP-binding protein of yersiniabactin-iron ABC transporter  ",{"$nulls":4},"+",{"$nulls":4},"+",180,"499-522 (L); 18-341 (L) incl. 18-28; 394-410 (L); 499-522 (L)",409,6.69,66593,"IM",null,5,null,"Y ","50-51","Transport and binding proteins","Unknown substrate","Yersiniabactin uptake / transport across inner membrane"]
[null,"y2397","ybtP",22126281,"NP_668869","Y","i-M","permease/ATP-binding protein of yersiniabactin-iron ABC transporter  ",{"$nulls":4},"+",{"$nulls":3},"+","+",56,"410-538 (L); 218-228 (L)",684,9.05,66300,"IM",null,6,null,"Y ","44-45","Unclassified","Role category not yet assigned","Yersiniabactin uptake / transport across inner membrane"]
[null,"y2452","(efeU)",22126335,"NP_668870",null,"i-M","cytochrome (putative iron/lead family transporter)",{"$nulls":4},"+",{"$nulls":4},"+",63,"271-281 (L); 271-281 (L)",null,6.96,31205,"IM",null,7,null,"N",null,"Unknown function","General","Putative membrane-bound iron permease (FTR 1 family) "]
[null,"y2552","manY",22126433,"NP_668871",null,"i-M","mannose-specific PTS enzyme IIC ",{"$nulls":4},"+",{"$nulls":4},"+",139,"129-279 (L); 262-279 (L); 262-279 (L)",553,5.48,29357,"IM",null,7,null,"N",null,"Transport and binding proteins","Carbohydrates, organic alcohols, and acids","Sugar phosphotransferase system for sorbose and mannose"]
[null,"y2553","manZ",22126434,"NP_668872",null,"i-M","mannose-specific PTS enzyme IID ",{"$nulls":4},"+",{"$nulls":4},"+",158,"106-199 (L); 24-199 (L); 24-199 (L)",579,9.42,32431,"IM",null,2,null,"N",null,"Transport and binding proteins","Carbohydrates, organic alcohols, and acids","Sugar phosphotransferase system for sorbose and mannose"]
[200,"y2596","lldD",22126477,"NP_668873",null,"i-M","L-lactate dehydrogenase  ",{"$nulls":3}," ","+",{"$nulls":3},"+",8327752,995,"1-381 (L) incl. 1-10; 1-330 (M) incl. 1-10; 1-372 (L)",null,7.82,41290,"U",null,0,null,"N",null,"Energy metabolism","Aerobic","Flavin mononucleotide-dependent dehydrogenase, functions in aerobic respiration"]
[260,"y2633","ysuR",22126512,"NP_669935"," ","i-M","TonB-dependent outer membrane iron/siderophore receptor ","N.A.","N.A.","N.A.","282531 (N/A)","+",{"$nulls":4},264332,202,"97-650 (L)",374,8.81,84014,"OM",4,0,null,"Y ","41-42","Transport and binding proteins","Cations and iron carrying compounds","TonB-dependent outer membrane receptor for iron / siderophore substrates "]
[null,"y2644","asmA",22126523,"NP_669946",null,"i-M","putative OM/lipopolysaccharide assembly protein ",{"$nulls":4},"+",{"$nulls":4},"+",123,"163-523 (L);  510-523 (L); 68-523 (L)",56,8.69,68057,"U",null,1,null,"Y ","26-27","Cell envelope","Other","Cell envelope protein possibly involved in outer membrane biogenesis, AsmA family "]
[85,"y2647","mrp",22126526,"NP_669949",null,"i-M","putative ATPase (multiple resistance and pH adaptation protein Mrp)","N.A.","N.A.","N.A.","162751 (29%)","+",{"$nulls":4},332654,213,"5-344 (M) incl. 5-20; 5-344 (L) incl. 5-20 ",null,5.43,40349,"U",null,0,null,"N",null,"Unknown function","General","Possibly involved in multiple resistance and pH adaptation (Fer4-NihF domain)"]
[null,"y2661","mglA",22126540,"NP_669963",null,"i-M","galactose/methyl galaxtoside transporter ATP-binding protein","N.A.","N.A.","2247113 (80%)","N.A.",{"$nulls":6},65,"2-223 (L) incl. 2-10 ",null,7.16,57084,"IM",null,0,null,"N",null,"Transport and binding proteins","Carbohydrates, organic alcohols, and acids","Component of inner membrane ABC transporter for galactose"]
[235,"y2677","(uup3)",22126556,"NP_668874"," ","i-M","ATP-binding component of ABC transport system ","N.A.","N.A.","N.A.","454341 (23%)","+",null,"+","+",null,914356,529,"102-587 (L); 86-568 (L); 102-568 (L); 249-489 (M)",96,5.27,66418,"IM",null,0,null,"N",null,"Transport and binding proteins","Unknown substrate","Putative membrane transport protein possibly involved in drug resistance"]
[null,"y2731","(yccF)",22126609,"NP_668875",null,"i-M","hypothetical protein y2731 (conserved inner membrane protein)",{"$nulls":4},"+",{"$nulls":4},"+",102,"129-139 (L)",135,9.65,16613,"IM",null,3,null,"N",null,"Unknown function","General","Conserved inner membrane protein similar to E. coli YccF"]
[253,"y2747","pqiB",22126625,"NP_670048","Y","i-M","paraquat-inducible protein B ","N.A.","N.A.","N.A.","823178 (45%)","+",null,null,"+","+",429464,295,"76-555 (L); 10-555 incl. 10-24; 87-555 (M) ",283,8.68,61743,"U",null,1,null,"N",null,"Unknown function","General","Putative secreted protein with paraquat B and MCE domains for colonization of host"]
[39,"y2750","uup",22126628,"NP_668876"," ","i-M","ABC transporter ATPase component  ","N.A.","N.A.","N.A.","884932 (17%)","+",null,"+",null,"+",857621,377,"66-641 (L); 66-430 (L)",null,5.62,73348,"IM",null,0,null,"N",null,"Transport and binding proteins","Unknown substrate","Putative membrane transport protein possibly involved in drug resistance"]
[null,"y2765","mukB",22126643,"NP_668877",null,"i-M","condesin subunit B (cell division protein MukB)",{"$nulls":4},"+",null,null,"+",null,"+",203,"1239-1442 (L)",157,5.28,170261,"C",null,0,null,"N",null,"Cellular processes","Cell division","Probably involved in chromosome partitioning / segregation during cell division"]
[76,"y2767","mukF",22126645,"NP_668878",null,"i-M","condesin subunit F ","N.A.","N.A.","N.A.","339378 (46%)","+",null,"+",null,null,315686,363,"90-251 (L)",null,4.82,50257,"C",null,0,null,"N",null,"Cellular processes","Toxin production and resistance","Probably involved in chromosome partitioning / segregation during cell division"]
[null,"y2814","(macA)",22126691,"NP_668879",null,"i-M","macrolide transporter subunit MacA",{"$nulls":4},"+",null,null,"+",null,null,81,"46-170 (L); 244-287 (L); 1-287 (L) incl. 1-6 ",60,6.93,40161,"IM",null,1,null,"N",null,"Cell envelope","Other","HlyD family membrane efflux pump; membrane fusion protein"]
[58,"y2826","(ybjP)",22126703,"NP_670126",null,"i-M","predicted lipoprotein","N.A.","N.A.","N.A.","635059 (38%)","+",{"$nulls":4},726481,348,"34-185 (L); 102-185 (M)",165,8.5,20894,"U ",null,0,"OM-LP","Y ","21-22","Cell envelope","Other","Putative lipoprotein  "]
[236,"y2836","(smtA3)",22126713,"NP_668880"," ","i-M","ABC transport protein (putative iron transport)","N.A.","N.A.","995921 (N/A)","520393 (N/A)","+",{"$nulls":3},"+",430984,162,"44-172 (L); 44-181 (L)",null,6.19,30066,"U",null,0,null,"N",null,"Hypothetical proteins","Conserved","ABC-type transporter with cation transport functions "]
[199,"y2864","dacC",22126741,"NP_668881",null,"i-M","D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 6)  ",{"$nulls":4},"+",{"$nulls":3},"+",9234988,600,"73-432 (L); 73-407 (M); 73-432 (L); 73-407 (M)",null,8.86,47535,"IM",null,0,null,"N",null,"Cell envelope","Biosynthesis and degradation of murein sacculus and peptidoglycan","Penicillin-binding protein 6"]
[null,"y2882","psaA",22126759,"NP_670182",null,"i-M","pH 6 antigen fimbrial subunit ",{"$nulls":9},"+",231,"39-163 (L)",null,5.52,17909,"E ",null,0,"OM-LP","Y","32-33","Cellular processes","Pathogenesis","Putative outer membrane protein and virulence factor"]
[40,"y2910","(oppA2)",22126787,"NP_670210"," ","i-M","hypothetical protein y2104 (putative ABC-type oligopeptide transporter) ",{"$nulls":4},"+",null,"1049100*",9320070,null,1699848,1039,"37-427 (L); 25-474 (L)",null,7.72,69129,"IM",null,0,null,"Y ","20-21","Unknown function","General","Periplasmic transport of oligopeptides"]
[195,"y2913","(yejF)",22126790,"NP_668882"," ","i-M","ATP-binding component of a transport system ",{"$nulls":4},"+",{"$nulls":3},"+",2351434,659,"235-430 (L); 61-541 (L)",null,8.26,60126,"IM",null,0,null,"N",null,"Transport and binding proteins","Amino acids, peptides and amines","Probably ATP-binding subunit of ABC transporter for dipeptides, oligopeptides and nickel"]
[261,"y2940","-",22126817,"NP_670240",null,"i-M","hypothetical protein y2940 (putative bacteriophage Mu P  protein)","N.A.","N.A.","N.A.","515506 (30%)","+",{"$nulls":4},534783,194,"1-290 (L) incl. 1-12; 29-349 (L)",null,5.39,38824,"U",null,0,null,"N",null,"Mobile and extrachromosomal element functions","Prophage functions","Mu-like prophage tail protein gpP "]
[41,"y2980","(yfaZ)",22126857,"NP_670280",null,"i-M","hypothetical protein y2980 ","N.A.","N.A.","N.A.","1871665 (72%)","+",{"$nulls":4},2399195,241,"83-160; 83-139 (M); 55-160 (L)",523,5.88,18713,"IM",4,0,null,"Y ","22-23","Unknown function","General","Homologous to predicted outer membrane porin (E. coli)"]
[null,"y3018","(ybhL)",22126895,"NP_668883",null,"i-M","hypothetical protein y3018  (putative FtsH-interacting protein)",{"$nulls":4},"+",{"$nulls":4},"+",81,"193-207 (L)",54,9.52,25875,"OM",null,7,null,"N ","(44-45)","Unknown function","General","putative integral membrane protein interacting with FtsH"]
[42,"y3041","modF",22126918,"NP_668884"," ","i-M","ATP-binding component of molybdate transport system ",{"$nulls":4},"+",{"$nulls":4},505971,72,"123-133 (L)",null,5.71,58239,"IM",null,0,null,"N",null,"Transport and binding proteins","Anions","ATP-binding subunit of ABC transporter for molybdate "]
[43,"y3058","tolQ",22126934,"NP_668885",null,"i-M","colicin uptake protein TolQ ","N.A.","N.A.","N.A.","327618 (62%)","+",{"$nulls":4},334128,64,"41-110 (L)",75,6.16,25348,"IM",null,3,null,"N",null,"Cellular processes","Toxin production and resistance","Component of cell division machinery and maintanance of OM integrity "]
[254,"y3074","ppnK",22126950,"NP_670373",null,"i-M","inorganic polyphosphate / ATP-NAD kinase ","N.A.","N.A.","N.A.","167313 (53%)","+",{"$nulls":4},229340,132,"65-82 (L)",null,6.04,32492,"U",null,0,null,"N",null,"Unclassified","Role category not yet assigned","Predicted sugar kinase"]
[262,"y3076","smpA",22126952,"NP_670375 ",null,"i-M","small membrane protein A ",{"$nulls":4},"+",{"$nulls":4},529620,112,"29-116 (L)",91,7.79,12939,"U ",null,0,"OM-LP","Y ","26-27","Unknown function","General","Lipid-anchored outer membrane protein in YaeT/YfgL/NlpB/SmpA complex; outer membrane protein assembly "]
[null,"y3104","metN",22126980,"NP_668886"," ","i-M","DL-methionine transporter ATP-binding subunit",{"$nulls":4},"+",null,null,"+","+",null,154,"161-270 (L)",null,6.56,37681,"IM",null,0,null,"N",null,"Transport and binding proteins","Unknown substrate","Probably ATP-binding subunit of ABC transporter for D-methionine  "]
[59,"y3106","metQ",22126982,"NP_670405"," ","i-M","DL-methionine ABC transporter substrate-binding protein","N.A.","N.A.","2246432(104%)","1506483 (48%)","+",null,576834,null,891630,1248005,201,"35-234 (M); 35-269 (L)",1095,5.38,29416,"U ",null,0,"IM-LP","Y ","23-24","Cell envelope","Other","Periplasmic metal ion transport protein (ABC transport) "]
[null,"y3110","cutF",22126986,"NP_670409",null,"i-M","lipoprotein involved with copper homeostasis and adhesion",{"$nulls":4},"+",null,"+",null,null,"+",344,"88-237 (M); 81-237 (L)",50,5.51,27204,"U",null,0,"OM-LP","Y ","35-36","Cellular processes","Detoxification","possibly involved in copper homeostasis and adhesion"]
[null,"y3235","lamB1",22127111,"NP_670534",null,"i-M","maltoporin ",{"$nulls":4},"+",{"$nulls":4},"+",85,"206-220 (L)",null,4.8,49044,"OM",2,0,null,"Y ","48-49","Transport and binding proteins","Carbohydrates, organic alcohols, and acids","Porin probably involved in maltose and maltodextrin transport"]
[null,"y3242","-",22127118,"NP_668887"," ","i-M","putative maltose ABC transporter ATP-binding protein ",{"$nulls":4},"+",null,null,"+","+","+",101,"229-238 (L)",null,6.15,41229,"C",null,0,null,"N",null,"Transport and binding proteins","Carbohydrates, organic alcohols, and acids","Putative component of ABC transporter for maltose"]
[null,"y3306","(mscS2)",22127182,"NP_668889",null,"i-M","transport protein (putative mechanosensitive channel)",{"$nulls":4},"+",{"$nulls":3},"+","+",99,"170-238 (L); 170-180 (L); 170-180 (L)",282,5.85,31092,"IM",null,3,null,"N",null,"Cell envelope","Other","Probably small conductance mechanosensitive ion channel "]
[86,"y3311","(yggG)",22127187,"NP_670610",null,"i-M","hypothetical protein y3311 (putative Zn-dependent protease) ","N.A.","N.A.","N.A.","2484938 (59%)","+",{"$nulls":4},3870136,259,"69-247 (L)",null,5.77,27897,"U ",null,0,"OM-LP","Y ","34-35","Unknown function","General","Zinc-denpendent protease with putative chaperone function  "]
[null,"y3341","mltC",22127217,"NP_670640",null,"i-M","membrane-bound lytic murein transglycosylase C ",{"$nulls":4},"+",{"$nulls":4},"+",88,"59-246 (L)",null,9.15,40470,"U ",null,0,"OM-LP","Y ","26-27","Cell envelope","Biosynthesis and degradation of murein sacculus and peptidoglycan","Lytic transglycosylase involved in peptidoglycan metabolism "]
[24,"y3385","iutA",22127261,"NP_670684"," ","i-M","TonB-dependent aerobactin outer membrane receptor ","N.A.","N.A.","N.A.","272429 (10%)","+",{"$nulls":4},205560,569,"92-712 (L)",null,5.19,80383,"OM",5,0,null,"Y ","24-25","Unclassified","Role category not yet assigned","TonB-dependent outer membrane receptor probably involved in for iron transport "]
[null,"y3494","exbD",22127368,"NP_668890","Y","i-M","biopolymer transport protein ExbD of TonB-complex  ",{"$nulls":4},"+",{"$nulls":3},2321698,"+",89,"130-143 (L); 130-143 (L); 130-143 (L)",135,4.6,15565,"IM",null,1,null,"N",null,"Transport and binding proteins","Other","Membrane-spanning protein in TonB-ExbB-ExbD complex"]
[null,"y3495","exbB",22127369,"NP_668891"," ","i-M","TonB complex protein ",{"$nulls":4},"+",{"$nulls":4},"+",166,"164-342 (L); 332-342 (L)",118,9.47,37106,"IM",null,4,null,"Y ","46-47","Transport and binding proteins","Cations and iron carrying compounds","TonB complex protein, required for energy-dependent transport of molecules across OM via OM receptors "]
[27,"y3560","cyaE",22127434,"NP_670875",null,"i-M","hypothetical protein y3560 (putative outer membrane efflux protein) ","N.A.","N.A.","N.A.","870295 (15%)","+",{"$nulls":4},609625,232,"174-439 (L)",null,6.35,53790,"OM",0,1,null,"N",null,"Transport and binding proteins","Unknown substrate","Outer membrane channel protein possibly involved in efflux of peptides / proteins "]
[null,"y3586","-",22127460,"NP_670883",null,"i-M","hypothetical protein y3586 ",{"$nulls":4},"+",null,null,"+",null,"+",163,"88-498 (L)",null,4.88,63408,"U",null,0,null,"N",null,"Hypothetical proteins","Conserved","Protein with unknown functions"]
[247,"y3622","ftsA",22127496,"NP_670919","Y","i-M","cell division protein FtsA","N.A.","N.A.","2221829 (56%)","1380982 (59%)","+",null,"+",null,884714,1980626,155,"145-408 (M); 127-357 (M); 8-415 (L) incl. 8-19 ",null,5.67,45797,"C",null,0,null,"N",null,"Cellular processes","Cell division","Actin-like ATPase involved in cell division "]
[248,"y3625","murC",22127499,"NP_670922",null,"i-M","UDP-N-acetylmuramate-L-alanine ligase ","N.A.","N.A.","N.A.","181237 (27%)","+",{"$nulls":4},146078,139,"124-399 (M); 124-399 (L); 15-342 (L) incl. 15-24 ",null,5.92,55628,"C",null,0,null,"N",null,"Cell envelope","Biosynthesis and degradation of murein sacculus and peptidoglycan","UDP-N-acetylmuramate-alanine synthase; inner membrane-associated peptidoglycan precursor biosynthesis"]
[87,"y3640","ilvI",22127514,"NP_670937",null,"i-M","acetolactate synthase 3 catalytic subunit  ","N.A.","N.A.","N.A.","257923 (23%)","+",null,null,"+",null,206488,191,"68-589 (L)",null,5.87,65110,"U",null,0,null,"N",null,"Amino acid biosynthesis","Pyruvate family","Isoleucine / leucine biosynthesis "]
[88,"y3656","hepA",22127530,"NP_670953",null,"i-M","ATP-dependent helicase HepA  ","N.A.","N.A.","N.A.","669486 (10%)","+",{"$nulls":4},212413,368,"2-968 (L) incl. 2-8 ",null,5.06,110514,"U",null,0,null,"N",null,"Transcription","Transcription factors","Involved in stimulation of RNA-polymerase recycling"]
[294,"y3658","-",22127532,"NP_668892",null,"i-M","putative type VI secretion system subunit y3658 (VasK-like component)","N.A.","N.A.","1449737 (N/A)  F","N.A.","+",{"$nulls":3},"+",null,63,"547-560 (L); 721 734 (L)",null,8.99,132769,"IM",null,3,null,"Y ","27-28","Unclassified","Role category not yet assigned","VasK-like type VI secretion system protein with Ras GTPase superfamily domain  "]
[null,"y3659","-",22127533,"NP_668893",null,"i-M","putative type VI secretion system subunit y3659 (VasF-like component)",{"$nulls":4},"+",{"$nulls":3},"+",null,57,"174-473 (L)",null,8.61,61519,"IM",null,1,null,"N",null,"Cell envelope","Other","VasF-like type VI secretion system protein with OmpA domain"]
[280,"y3660","-",22127534,"NP_670957",null,"i-M","hypothetical protein y3660  ",{"$nulls":4},"+",{"$nulls":3},2314352,"+",134,"32-404 (L)",null,5.59,51448,"U",null,0,null,"N",null,"Hypothetical proteins","Conserved","Protein with unknown functions"]
[298,"y3664","-",22127538,"NP_670961",null,"i-M","putative type VI secretion system subunit y3664","N.A.","N.A.","864260 (50%)","N.A.","+",{"$nulls":3},"+","+",117,"1-365 (L) incl. 1-15  ",null,5.7,42413,"U",null,0,null,"N",null,"Unknown function","General","Pentapeptide repeat motif containing protein, in type VI secretion system gene locus"]
[273,"y3665","-",22127539,"NP_670962",null,"i-M","hypothetical protein y3665",null,null,"1795177 (5%)",null,"+",null,"+","+",1821830,"+",293,"3-727 (L) incl. 3-13; 392-408 (L)",null,5.35,84654,"U",null,0,null,"N",null,"Cell envelope","Other","Pentapeptide repeat motif containing protein, in type VI secretion system gene locus"]
[302,"y3668","(vgrG5)",22127540,"NP_670963",null,"i-M","hypothetical protein y3668 (putative type VI secretion system subunit)","N.A.","N.A.","N.A.","213776 (58%)","+",{"$nulls":3},"+","+",406,"56-538 (L); 228-525 (L)",null,5.16,85601,"U",null,0,null,"N",null,"Unknown function","General","Protein with unknown functions, Rhs element Vgr protein "]
[295,"y3671","-",22127545,"NP_670968",null,"i-M","putative type VI secretion system subunit y3671 (VasA-like component)","N.A.","N.A.","213380 (86%)","N.A.","+",null,"+",null,234000,null,241,"117-607 (L)",null,6.25,69095,"C",null,0,null,"N",null,"Hypothetical proteins","Conserved","VasA-like type VI secretion system protein"]
[89,"y3674","-",22127548,"NP_670971","Y","i-M","hypothetical protein y3674 (putative type VI secretion system subunit)","N.A.","966398 (6%)","18206538 (43%)","2752385 (181%)","+",{"v":21.173490126871034,"d":"21.1735"},"+",1188987,12318088,4207184,493,"80-401 (M); 45-418 (L); 46-470 (M); 36-470 (L); 45-358 (L)",61,5.28,57354,"U",null,0,null,"N",null,"Hypothetical proteins","Conserved","Protein with unknown functions; domain predicted to be component of type VI secretion system"]
[211,"y3675","-",22127549,"NP_670972","Y","i-M","hypothetical protein y3675 (putative type VI secretion system subunit)","984852 (40%)","3439858 (55%)","7390156 (76%)","1984869 (120%)",{"v":0.3640564869456905,"d":"0.3641"},{"v":3.048062841209495,"d":"3.0481"},895257,null,12644894,1651334,426,"51-140 (M); 33-186 (L)",147,4.52,21076,"C",null,0,null,"N",null,"Unknown function","General","Predicted component of type VI protein secretion system"]
[290,"y3676","-",22127550,"NP_670973",null,"i-M","putative type VI secretion system subunit y3676 ","N.A.","N.A.","989489 (42%)","N.A.","+",{"$nulls":3},1024780,"+",146,"65-281 (L); 65-281 (L)",null,4.8,39103,"C",null,0,null,"N",null,"Hypothetical proteins","Conserved","Secretion system involved in export of cytotoxins"]
[null,"y3731","(ompA5)",22127605,"NP_671028",null,"i-M","outer membrane lipoprotein  ",{"$nulls":4},"+",{"$nulls":4},"+",63,"141-168 (L)",50,9.71,18610,"OM",null,1,"OM-LP","Y","31-32","Cell envelope","Other","Palmitoylation on C-19"]
[null,"y3737","sms",22127609,"NP_670826",null,"i-M","ATP-dependent protease ",{"$nulls":4},"+",{"$nulls":3},"+","+",144,"51-223 (L); 329-337 (L)",55,6.77,49985,"U",null,0,null,"N",null,"DNA metabolism","DNA replication, recombination, and repair","Involved in protein turnover or DNA repair (similar to DNA repair protein RadA)"]
[null,"y3760","-",22127631,"NP_671054",null,"i-M","multidrug resistance protein  (putative macrolide transporter)",{"$nulls":4},"+",null,null,"+",null,"+",111,"98-285 (L)",88,6.62,36847,"C",null,0,null,"N",null,"Transport and binding proteins","Other","Protein possibly involved in membrane fusion and macrolide drug transport "]
[34,"y3803","(typA) ",22127674,"NP_671097"," ","i-M","GTP-binding factor BipA/TypA","481235 (9%)","281899 (146%)","493135 (22%)","1691538 (18%)",{"v":0.26203548641596985,"d":"0.2620"},{"v":16.37287905440651,"d":"16.3729"},594348,401227,496178,1728600,667,"7-541 (L) incl. 7-18; 7-597 (M) incl. 7-18; 25-562 (L)",448,5.22,67452,"C",null,0,null,"N",null,"Unknown function","General","Predicted membrane GTPase coordinating virulence gene expression and cell motilitiy inE. coli "]
[null,"y3864","-",22127735,"NP_668895",null,"i-M","hypothetical protein y3864 (putative 2-component regulator subunit) ",{"$nulls":4},"+",{"$nulls":4},"+",68,"2-823 (M) incl. 2-13",null,6.53,94816,"IM",null,2,null,"Y","38-39","Regulatory functions","Protein interactions","putative histidine kinase of two-component regulatory system"]
[309,"y3891","glpD",22127762,"NP_671185","Y","i-M","sn-glycerol-3-phosphate dehydrogenase",{"$nulls":4},"+",{"$nulls":3},2443442,null,116,"83-462 (M)",null,6.57,60515,"C",null,0,null,"N",null,"Energy metabolism","Aerobic","Converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxyacetone phosphate and ubiquinol-8"]
[null,"y3924","mrcA",22127794,"NP_668896",null,"i-M","peptidoglycan synthetase (penicillin-binding protein 1A)",{"$nulls":4},"+",{"$nulls":4},"+",67,"761-779 (L); 242-252 (L)",68,7.22,94748,"MSL",null,1,null,"Y","36-37","Cell envelope","Biosynthesis and degradation of murein sacculus and peptidoglycan","Carboxypeptidase / transglycosylase with large periplasmic domain with role in cell shape (L. monocytogenes)"]
[null,"y3936","damX",22127805,"NP_671228",null,"i-M","hypothetical protein y3936 (putative cell division interference protein)",{"$nulls":4},"+",null,"+",null,null,"+",160,"239-279 (L)",80,9.34,34635,"U",null,1,null,"N",null,"Cellular processes","Cell division","Putative membrane protein possibly involved in cell division "]
[null,"y3948","(cirA1)",22127818,"NP_671241",null,"i-M","putative outer membrane receptor protein CirA",{"$nulls":4},"+",{"$nulls":4},"+",398,"88-649 (L)",null,9.03,75019,"OM",2,1,null,"Y","32-33","Cell envelope","Other","TonB-dependent outer membrane receptor probably for iron transport  "]
[90,"y4020","trkA",22127890,"NP_668897",null,"i-M","potassium transporter peripheral membrane component ","N.A.","N.A.","1081724 (10%)","N.A.","+",null,"+",null,1011326,603566,140,"220-429 (L)",null,5.34,50313,"U",null,0,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","Peripheral inner membrane protein for potassium transport across IM "]
[256,"y4043","(fecB3)",22127913,"NP_668898"," ","i-M","solute-binding iron ABC transport protein ","N.A.","N.A.","464210 (68%)","1178739 (75%)","+",null,"+",null,null,987304,303,"163-329 (L); 82-329 (L); 194-329 (L)",154,5.37,35511,"P ",null,0,"IM-LP","Y","37-38","Transport and binding proteins","Cations and iron carrying compounds","Periplasmic siderophore / iron-binding protein with cytoplasmic lipid anchor motif"]
[263,"y4088","-",22127957,"NP_671380",null,"i-M","hypothetical protein y4088 (putative outer membrane lipoprotein)","N.A.","N.A.","N.A.","1965993 (121%)","+",null,"+",null,"+",112455,80,"57-234 (L); 53-145",145,9.16,26928,"U",null,1,"OM-LP","Y","31-32","Cell envelope","Other","Putative outer membrane lipoprotein (S. typhimurium)"]
[null,"y4117","yidC",22127984,"NP_668899",null,"i-M","putative inner membrane protein translocase component YidC ",{"$nulls":4},"+",{"$nulls":4},"+",75,"48-300 (L)",243,8.54,61309,"IM",null,5,null,"Y","25-26","Cell envelope","Other","Subunit YidC of preprotein translocase "]
[237,"y4128","pstB",22127996,"NP_668900"," ","i-M","ATP-binding protein of high-affinity phosphate ABC transporter ","N.A.","N.A.","845613 (119%)","314811 (122%)","+",{"$nulls":3},923628,8734878,221,"17-257 (M) incl. 17-24; 17-257 (M); 17-257 (L); 17-257 (L) incl. 17-24 ",null,5.62,29381,"MSL",null,0,null,"N",null,"Transport and binding proteins","Anions","Phosphate uptake regulator, inorganic ion transport, peripheral membrane protein B"]
[null,"y4141","atpB",22128009,"NP_668901",null,"i-M","F0F1 ATP synthase subunit A",{"$nulls":4},"+",{"$nulls":3},"+","+",104,"2-77 (L); 2-77 (L) incl. 2-11; 2-77 (L) incl. 2-11",121,6.29,30391,"IM",null,5,null,"N",null,"Energy metabolism","ATP-proton motive force interconversion","Subunit of proton-transporting membrane ATP synthase complex"]
[null,"y4144","gidA",22128012,"NP_668902",null,"i-M","glucose-inhibited division protein A ",{"$nulls":4},"+",{"$nulls":4},"+",126,"202-630 (L); 202-630 (L); 202-630 (L)",null,6.4,73325,"U",null,0,null,"N",null,"No Data","No Data","Involved in cell division and chromosome partitioning "]
[196,"YPKMT066","caf1A",31795235,"NP_857693",null,"i-M","fimbrial usher protein of F1 capsule antigen",{"$nulls":4},"+",{"$nulls":4},7031314,583,"64-824 (L)",null,9.13,93401,"OM",1,0,null,"Y","22-23","Motility and secretion / Intracellular trafficking and secretion","Protein folding and stabilization","Capsular biogenesis, outer membrane fimbrial usher protein and porin PapC"]
[282,"Y1020",null,31795351,"NP_667381",null,"i-M","hypothetical protein Y1020 ",{"$nulls":4},"+",{"$nulls":3},"+",null,91,"40-52 (L)",null,8.52,14970,"U",null,0,"OM-LP","Y","30-31","Cell envelope","Other","Protein of unknown function expressed by virulence plasmid pMT1"]
[1,"y0032","lamB",22123953,"NP_667376","Y","i-OM","maltoporin","N.A.","N.A.","10214227 (32%)","11073878 (35%)","+",{"$nulls":3},4546530,4615456,751,"89-463 (M); 89-463 (L); 152-463; 114-463",586,6.02,53392,"OM",4,0,null,"N",null,"Transport and binding proteins","Carbohydrates, organic alcohols, and acids","Porin involved in maltose and maltodextrin import and receptor for lambda phage"]
[32,"y0221","slyB",22124141,"NP_667564",null,"i-OM","outer membrane receptor ","N.A.","N.A.","N.A.","1440868 (23%)","+",{"$nulls":3},"+",10459578,390,"84-157 (L); 84-135 (M)",2621,11.12,15504,"U ",null,0,"OM-LP","Y","28-29","Cell envelope","Other","Putative outer membrane lipoprotein, possibly involved in haemolysis with SlyA "]
[4,"y0325","btuB",22124242,"NP_667665",null,"i-OM","vitamin B12/cobalamin outer membrane transporter ","N.A.","N.A.","N.A.","2795862 (61%)","+",{"$nulls":3},"+",1348680,672,"73-556; 73-653 (L)",1203,5.28,73080,"OM",3,0,null,"N",null,"Cell envelope","Other","TonB-dependent outer membrane receptor for small molecule transport "]
[5,"y0396","pldA",22124311,"NP_667734",null,"i-OM","outer membrane phospholipase A","N.A.","N.A.","994775 (46%)","3740599 (29%)","+",{"$nulls":3},"+",2669708,376,"28-236 (M); 28-292 (L); 28-292; 28-236",240,5.03,33738,"OM",1,0,null,"Y","21-22","Central intermediary metabolism","Other","Phosphatidylcholine / phospholipid hydrolysis (E. coli)"]
[6,"y0543","hmuR",22124457,"NP_667880"," ","i-OM","TonB-dependent outer membrane receptor (hemin uptake) ","N.A.","N.A.","647584(28%)","2189852 (79%)","+",null,489725,null,410094,2428418,1064,"41-666; 86-666; 40-666 (L); 86-666 (M)",1673,5.06,74241,"OM",4,0,null,"Y","29-30","Unclassified","Role category not yet assigned","TonB-dependent outer membrane receptor for hemin / iron uptake  (P. ginigvalis)"]
[213,"y0659","-",22124573,"NP_667996",null,"i-OM","hypothetical protein y0659 ( putative outer membrane protein)",{"$nulls":3},"1872581 (69%)","+",{"$nulls":4},2818358,1011,"59-514 (M); 26-553 (L)",618,6.37,64480,"OM",null,0,null,"Y","22-23","Unknown function","General","Variable number repeat outer membrane surface antigen  "]
[7,"y0850","(cirA2)",22124761,"NP_668184"," ","i-OM","TonB-dependent outer membrane receptor (iron transport) ","N.A.","N.A.","560490 (70%)","144755682 (22%)","+",null,"+",null,"+",6758196,669,"73-721 (M); 76-646 (L); 73-721; 73-646",1847,6.38,80093,"OM",5,0,null,"Y","54-55","Cell envelope","Other","TonB-dependent outer membrane receptor with probable iron / ferroenterochelin transport function"]
[8,"y1324","ail",22125223,"NP_668646","Y","i-OM","adhesion and invasion locus protein Ail","N.A.","N.A.","2604545 (74%)","104007600 (25%)","+",null,"+","+",4751030,8436810,1145,"53-193 (L); 90-194 (M); 66-193; 53-194; 71-194; 53-194; 53-194 ",null,8.51,21612,"OM",5,1,null,"Y","39-40","DNA metabolism","DNA replication, recombination, and repair","Putative virulence factor, attachment invasion locus protein Ail (Y. pseudotuberculosis YPTB2867)"]
[56,"y1419","nlpB",22125317,"NP_668740","Y","i-OM","lipoprotein ",{"$nulls":4},"+",null,483255,"+","+",7760862,647,"40-336 (M); 107-324; 107-324 (M); 70-324 (L); 227-324 (L)",199,5.85,38492,"U  ",null,0,null,"N",null,"Cell envelope","Other","Outer membrane lipoprotein part of the YaeT/YfiO/YfgL assembly complex "]
[9,"y1577","fadL",22125472,"NP_668895",null,"i-OM","long-chain fatty acid outer membrane transporter   ","N.A.","N.A.","N.A.","5479953 (100%)","+",null,"+",null,"+",12398324,1008,"43-409 (M) ;43-409 (L) ;43-409; 43-409; 43-409; 43-409; 43-409 ",1833,4.82,45670,"OM",5,0,null,"Y","28-29","Transport and binding proteins","Carbohydrates, organic alcohols, and acids","Transport of hydrophobic compounds across outer membrane"]
[10,"y1682","ompX",22125577,"NP_669000","Y","i-OM","outer membrane protein X  ","N.A.","755693 (102%)","4667578 (128%)","16877748 (56%)","+",{"v":60.69153651327403,"d":"60.6915"},null,1279335,3578798,23303768,487,"56-159 (M); 47-127 (L); 56-127; 47-127; 56-127; 47-176; 56-127; 47-176",2879,5.85,18951,"OM",5,1,null,"Y","27-28","Mobile and extrachromosomal element functions","Prophage functions","Involved in mammalian cell adhesion and deactivation of human complement, opacity protein "]
[12,"y2167","mipA",22126055,"NP_669478","Y","i-OM","hypothetical protein y2167 (outer membrane protein V) ","N.A.","N.A.","N.A.","5848968 (19%)","+",null,"+",null,1845438,10568340,643,"53-256 (M); 53-185 (L); 53-185; 53-256; 70-185; 53-234",95,6.12,28967,"OM",3,1,null,"Y","31-32","Unknown function","General","Possibly involved in scaffolding for murein synthesis (S. typhimurium), may interact with murein transglycosylase MltA"]
[57,"y2358","hmsF",22126242,"NP_669665"," ","i-OM","hemin storage system, biofilm formation protein HmsF","N.A.","4981545 (41%)","16940075 (36%)","18472781 (14%)","+",{"v":11.84438155651113,"d":"11.8444"},368931,null,1833178,3754294,476,"151-673 (M); 151--657 (L)",254,5.61,76722,"U ",null,0,"OM-LP","Y","25-26","Regulatory functions","Other","Hemin storage system, predicted polysaccharide (xylanase/chitin) deacetylase "]
[13,"y2359","hmsH",22126243,"NP_669666",null,"i-OM","hemin storage system, biofilm formation protein HmsH","N.A.","1072831 (18%)","444554 (3%)","15493887 (13%)","+",{"v":36.581446528358256,"d":"36.5814"},"+",null,355974,4617186,1087,"105-843 (M); 68-770 (L); 496-805; 68-753; 105-805; 68-805",1103,5.38,95915,"OM",2,0,null,"N",null,"Unclassified","Role category not yet assigned","Involved in biofilm formation in Y. pestis in flea vector life cycle"]
[14,"y2404","psn",22126288,"NP_669711","Y","i-OM","pesticin/yersiniabactin outer membrane receptor ","N.A.","1183093 (45%)","22101023 (118%)","7956065 (42%)","+",{"v":30.792125229338268,"d":"30.7921"},"+",null,5206338,36896088,2801,"144-641 (M); 43-669 (L) ; 43-673; 144-610; 43-669",11208,5.54,73850,"OM",1,0,null,"Y","23-24","Unclassified","Role category not yet assigned","TonB-dependent outer membrane receptor for pesticin and yersiniabactin"]
[15,"y2556","fcuA",22126437,"NP_669860"," ","i-OM","TonB-dependent outer membrane ferrichrome receptor ","N.A.","N.A.","N.A.","1937878 (11%)","+",{"$nulls":4},2415598,801,"79-532 (M); 63-776 (L)",1019,6.75,84153,"OM",4,0,null,"Y","55-56","Transport and binding proteins","Cations and iron carrying compounds","TonB-dependent outer membrane receptor for iron / siderophore substrates "]
[16,"y2735","ompA",22126613,"NP_670036","Y","i-OM","outer membrane protein A ","N.A.","12172606 (55%)","33557157 (30%)","163764046 (28%)","+",{"v":35.841718370990016,"d":"35.8417"},"+",5702731,14028582,5487056,2001,"44-345 (M); 35-363 (L); 35-363;35-363; 44-352; 35-346; 35-363",14008,8.63,39363,"OM",0,1,null,"Y","32-33","Cell envelope","Other","Physically linked to peptidoglycan providing structural support to the outer membrane "]
[17,"y2759","ompF",22126637,"NP_670060","Y","i-OM","outer membrane porin protein OmpF","N.A.","4740014 (17%)","N.A.","95252551 (73%)","+",{"v":50.47220647498627,"d":"50.4722"},null,5776593,12247900,21024872,870,"45-347 (M); 123-347 (L); 45-347; 45-338",3501,4.71,41266,"OM",5,1,null,"Y","39-40","Cell envelope","Other","Outer membrane channel protein with small molecule import functions"]
[18,"y2872","yiuR",22126749,"NP_670172"," ","i-OM","outer membrane iron/siderophore receptor ","N.A.","N.A.","N.A.","3807653 (44%)","+",null,"+",null,"+",1891350,947,"32-650 (L)",1138,5.94,73978,"OM",4,0,null,"Y","29-30","Cell envelope","Other","TonB-dependent outer membrane receptor for iron / siderophore substrates "]
[19,"y2966","ompC",22126843,"NP_670266","Y","i-OM","outer membrane porin protein OmpC ","N.A.","679816 (15%)","1682828 (79%)","18766114 (35%)","+",{"v":71.1748954778735,"d":"71.1749"},null,705487,1170670,13408390,1770,"31-356 (M); 31-356 (L); 41-356; 31-374; 31-356; 31-356; 41-356; 31-374 ",624,4.83,41383,"OM",5,0,null,"Y","25-26","Cell envelope","Other","Outer membrane channel protein with small molecule import functions"]
[20,"y2983","phoE ",22126860,"NP_670283",null,"i-OM","outer membrane porin  protein PhoE","N.A.","661979 (4%)","N.A.","18221486 (38%)","+",{"v":69.13450841217933,"d":"69.1345"},null,null,"+",53554888,874,"28-356 (M); 28-356 (L); 40-345; 32-356;",3444,5.53,40664,"OM",5,0,null,"Y","22-23","Cell envelope","Other","Outer membrane channel protein with putative anion (phosphate) transport functions"]
[21,"y3054","pal",22126930,"NP_670353",null,"i-OM","peptidoglycan-associated outer membrane lipoprotein  ","N.A.","N.A.","5575987 (93%)","1669487 (146)","+",null,"+","+",3016504,4196022,548,"55-160 (M); 55-107; 27-168 (L)",3690,6.3,18130,"OM ",null,0,"OM-LP","Y","28-29","Cell envelope","Other","Involved in cell division forming the Tol-Pal trans-envelope complex"]
[22,"y3127","(yaeT)",22127003,"NP_670426","Y","i-OM","outer membrane protein assembly factor YaeT ","N.A.","N.A.","4536122 (40%)","10445714 (36%)","+",null,"+",209552,920068,7737940,2226,"37-793 (M); 37-793 (L); 37-747; 37-793; 37-793; 37-793; 37-631 ",1795,5.42,87784,"OM",4,1,null,"Y","21-22","Cell envelope","Other","Involved in assembly of outer membrane proteins and autotransporters "]
[23,"y3343","-",22127219,"NP_670642","Y","i-OM","TonB-dependent outer membrane receptor (ferrichrome-iron transport) ","N.A.","N.A.","N.A.","1284606 (94%)","+",null,4246709,null,"+",1636486,1042,"82-735 (L); 82-706; 158-706 (M)",437,6.05,83079,"OM",1,1,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","TonB-dependent outer membrane receptor for iron / siderophore substrates "]
[208,"y3404","-",22127280,"NP_670703"," ","i-OM","TonB-dependent outer membrane receptor","N.A.","N.A.","2813873 (3%)","3920841 (74%)","+",{"$nulls":3},722486,3019934,1390,"85-675 (M); 50-675 (L) ",467,5.29,79066,"OM",5,0,null,"Y","22-23","Transport and binding proteins","Cations and iron carrying compounds","TonB-dependent outer membrane receptor probably involved in for iron transport "]
[25,"y3480","papC",22127354,"NP_670777",null,"i-OM","outer membrane usher protein (P-pilus assembly protein)","N.A.","N.A.","N.A.","160146 (80%)","+",{"$nulls":4},163750,178,"275-685 (L)",null,5.01,90429,"OM",1,0,null,"Y","25-26","Protein fate","Protein folding and stabilization","P-pilus assembly protein in outer membrane"]
[26,"y3516","tolC ",22127390,"NP_670813","Y","i-OM","outer membrane channel protein (efflux system component TolC)","N.A.","N.A.","1341105 (83%)","4009656 (32%)","+",null,"+",2444894,1658398,10611994,1120,"36-465 (L); 60-422 (M); 60-422; 36-465; 60-422; 36-465 ",2362,7.75,50902,"OM",0,0,null,"Y","25-26","Cellular processes","Cell division","Outer membrane protein involved in efflux of hydrophobic / amphipathic molecules "]
[28,"y3680","imp",22127554,"NP_670977",null,"i-OM","organic solvent tolerance protein ","N.A.","N.A.","N.A.","3733905 (30%)","+",{"$nulls":3},600774,1979068,598,"173-767; 114-767; 219-716 (M);  114-716 (L)",779,7.08,89405,"OM",1,0,null,"Y","37-38","Cellular processes","Adaptations to atypical conditions","Facilitates lipopolysaccharide assembly in the outer leaflet of the outer membrane"]
[206,"y4083","-",22127952,"NP_671375 ",null,"i-OM","hypothetical protein y4083 (putative secreted protein)",{"$nulls":3},"344758 (333%)","+",null,"+","+",null,1419292,219,"51-127 (M); 51-127 (L)",null,5.91,17449,"U",null,1,null,"Y","19-20","Hypothetical proteins","Conserved","Putative secreted protein  "]
[31,"YPKp07","pla",31795332,"NP_857784",null,"i-OM","plasminogen activator/outer membrane protease ","N.A.","N.A.","17710642 (75%)","13129757 (204%)","+",null,"+","+",3751472,6528534,1792,"47-311 (M); 47-312 (L); 47-300; 47-312; 47-269; 47-311 ",854,5.9,35798,"OM",5,0,null,"Y","21-22","Pathogenesis","Degradation of proteins, peptides, and glycopeptides","Omptin family serine protease (fibrinolysis and coagulase)"]
[204,"YP_2181","lpp",45436836,"AAS62389",null,"i-OM","major outer membrane lipoprotein",{"$nulls":4},"+",{"$nulls":4},19437934,496,"30-80 (M);  30-81 (L)",null,8.93,8727,"OM",null,0,"OM-LP","Y","29-30","Outer membrane biogenesis",null,"anchors outer membrane and peptidoglycan for structural support of OM"]
[285,"y0037","-",22123958,"NP_667381",null,"p-M","putative type VI secretion system subunit y0037","N.A.","1132777 (38%)","807131 (33%)","N.A.","+",{"v":0.5302505505558259,"d":"0.5303"},"+",null,915178,null,331,"45-158 (L)",null,4.97,18510,"U",null,0,null,"N",null,"Unknown function","General","Secretion system involved in export of cytotoxins"]
[188,"y0067","cpxR",22123988,"NP_667411",null,"p-M","DNA response regulator in two-component regulatory system with CpxA ","1971283 (50%)","2000878 (122%)","N.A.","N.A.",{"v":0.026135066945564233,"d":"0.0261"},null,1370063,1194489,null,"+",195,"65-240 (L)",null,5.47,27507,"C",null,0,null,"N",null,"Regulatory functions","Other","Two-component regulator with CpxA; involved in regulation of stress response in cell envelope"]
[301,"y0084","rfaF",22124004,"NP_667427",null,"p-M","ADP-heptose-LPS heptosyltransferase II ","N.A.","5302085 (11%)","1644217 (89%)","199253 (52%)","+",{"v":0.3251650518967626,"d":"0.3252"},null,null,515552,null,157,"126-355 (L)",null,6.47,40245,"U",null,0,null,"N",null,"Cell envelope","Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides","Enzyme involved in outer membrane lipopolysaccharide core biosynthesis"]
[128,"y0098","(yicC)",22124018,"NP_667441","Y","p-M","hypothetical protein y0098 (putative stress-induced protein) ","N.A.","465219 (107%)","N.A.","N.A.","+",null,3448674,4142070,"+",602520,471,"62-259 (L); 31-287 (L)",null,5.16,33379,"C",null,0,null,"N",null,"Hypothetical proteins","Conserved","Putative stress-induced protein "]
[113,"y0137","degQ",22124057,"NP_667480","Y","p-M","periplasmic serine endoprotease  ","N.A.","2631063 (34%)","307383 (118%)","N.A.","+",{"v":0.08694209889116443,"d":"0.0869"},"2330474*",29190296,699780,3921384,884,"55-463 (L); 55-463 (M)",75,8.51,48149,"P",null,1,null,"Y","34-35","Protein fate","Degradation of proteins, peptides, and glycopeptides","Serine protease with chaperone function involved in folding / degradation of periplasmic and outer membrane proteins"]
[315,"y0163","(yjgF)",22124083,"NP_667506",null,"p-M","similar to E. coli ketoacid-binding protein YjgF ","N.A.","7941785 (7%)","N.A.","N.A.","+",null,"+",null,"+",null,480,"52-140 (L)",null,9.1,15157,"U",null,0,null,"N",null,"Cellular processes","Cell division","Salmonella typhimurium ortholog is proposed to have protective function with respect to ketoacid imbalance "]
[117,"y0194","-",22124114,"NP_667537",null,"p-M","putative carbon-nitrogen hydrolase  ",{"$nulls":4},"+",null,"+",21860578,null,null,544,"3-289 (M) incl. 3-18; 19-256 (L) incl. 19-29",52,7.83,32424,"U",null,0,null,"N",null,"Central intermediary metabolism","Other","Predicted aminohydrolase; may hydrolyse cyanide; detoxification"]
[276,"y0391","-",22124306,"NP_667729"," ","p-M","putative ABC transporter ATP-binding protein","4277116 (20%)","934947 (60%)","2862945 (5%)","N.A.",{"v":0.018454564238156723,"d":"0.0185"},{"v":2.278806949410215,"d":"2.2788"},3155458,null,1165180,"+",82,"2-405 (M) incl. 2-14; 45-405 (M); 2-405 (L) incl. 2-14; 2-405 (L)",91,5.04,44013,"C",null,0,null,"N",null,"Hypothetical proteins","Conserved","Protein of unknown function  "]
[186,"y0542","hmuS",22124456,"NP_667879",null,"p-M","hemin uptake system component ","N.A.","910462 (42%)","N.A.","N.A.","+",null,1146508,1593470,"+",null,156,"23-203 (M)",null,5.51,39124,"U",null,0,null,"N",null,"Transport and binding proteins","Unknown substrate/ Amino acids, peptides and amines/ Cations and iron carrying compounds","Involved in hemin uptake / degradation"]
[183,"y0546","-",22124460,"NP_667883",null,"p-M","orfX protein in hemin uptake locus (putative heme iron utilization protein)","N.A.","722234 (94%)","792535 (29%)","N.A.","+",{"v":0.8166238204959793,"d":"0.8166"},"+",1877781,576656,null,115,"52-112 (L); 1-151 incl. 1-15 (L)",null,5.86,20245,"U",null,0,null,"N",null,"Hypothetical proteins","Conserved","Putative heme iron utilization protein "]
[152,"y0556","terA",22124470,"NP_667893",null,"p-M","tellurium resistance protein  ","N.A.","765042 (27%)","1340243 (91%)","515357 (54%)","+",{"v":2.9956200611086685,"d":"2.9956"},"+",743070,null,null,261,"1-365 (L) incl. 1-19 ",null,6.02,42794,"U",null,0,null,"N",null,"Cellular processes","Adaptations to atypical conditions","Possibly involved in stress response, Colicin and tellurite resistance"]
[118,"y0596","-",22124510,"NP_667933",null,"p-M","hypothetical protein y0596 ",{"$nulls":4},"+",null,null,28168394,null,null,114,"95-109 (M)",null,8.67,16086,"U",1,0,null,"Y","21-22","Cell envelope","Other","Putative pertussis-like exported toxin "]
[null,"y0606","aspA",22124520,"NP_667943",null,"p-M","aspartate ammonia-lyase (aspartase) ","N.A.","4502915 (7%)","7772803 (50%)","N.A.","+",{"v":1.28459265495434,"d":"1.2846"},"+",null,null,"+",982,"7-205 (M) incl. 7-15; 7-478 (L) incl. 7-15",null,5.26,53318,"C",null,0,null,"N",null,"Hypothetical proteins","Conserved","Aspartase reversibly catalyzes the amination of fumarate to generate L-aspartate, observed in membrane fraction "]
[299,"y0616","frdB",22124530,"NP_667953",null,"p-M","fumarate reductase iron-sulfur subunit ","N.A.","10418964 (24%)","16513203 (12%)","N.A.","+",{"v":1.179473818684272,"d":"1.1795"},null,null,648554,null,418,"46-229 (M); 46-229 (L); 218-229 (L)",null,6.59,28098,"C",null,0,null,"N",null,"Energy metabolism","Anaerobic","Catalysis of the fumarate and succinate interconversion in the anaerobic respiration"]
[243,"y0617","frdA",22124531,"NP_667954",null,"p-M","fumarate reductase flavoprotein subunit","1334573 (59%)","10555448 (20%)","200276 (53%)","N.A.",{"v":0.20652643833138656,"d":"0.2065"},{"v":0.014119969578852816,"d":"0.0141"},1013438,null,577456,1834760,350,"1-591 (L) incl. 1-19; 20-591 (L) incl. 20-32; 1-563 (M) incl. 1-19 ",null,5.87,67421,"P",null,0,null,"Y","24-25","Energy metabolism","Electron transport","Flavoprotein; involved in anaerobic respiration and possibly associated with SdhA-D complex"]
[170,"y0686","(yhbC)",22124600,"NP_668023",null,"p-M","hypothetical protein y0686 ","N.A.","2456977 (22%)","N.A.","N.A.","+",null,null,3272643,null,null,171,"98-136 (L)",null,4.63,17074,"C",null,0,null,"N",null,"Unclassified","Role category not yet assigned","Has RNA binding pocket"]
[63,"y0696","deaD",22124610,"NP_668033",null,"p-M","inducible ATP-independent RNA helicase ","N.A.","1430112 (66%)","N.A.","853669 (11%)","+",{"v":1.499252424789758,"d":"1.4993"},"+",1843281,"+",312148,371,"51-450 (L);  63-411 (M);  51-369 (L)",null,9.1,74039,"C",null,0,null,"N",null,"Transcription","Transcription factors","DEAD box family DNA-binding protein involved in RNA metabolism "]
[229,"y0722","phnM",22124636,"NP_668059",null,"p-M","phosphonate metabolism protein ","N.A.","N.A.","N.A.","N.A.","+",{"$nulls":4},2953496,179,"114-333 (L); 114-372 (L); 114-372 (M)",null,5.7,41257,"C",null,0,null,"N",null,"Central intermediary metabolism","Phosphorus compounds","Metal-dependent hydrolase, a subunit of membrane C-P lyase complex"]
[317,"y0733","nrdD",22124647,"NP_668070  ",null,"p-M","anaerobic ribonucleoside triphosphate reductase","N.A.","1552528 (51%)","1987511 (22%)","N.A.","+",{"v":0.952690034246321,"d":"0.9527"},null,null,3908136,"+",668,"45-583 (L); 45-570 (L)",null,6.21,80901,"C",null,0,null,"N",null,"Purines, pyrimidines, nucleosides, and nucleotides","2'-Deoxyribonucleotide metabolism","Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates            "]
[189,"y0766","pdhR",22124679,"NP_668012",null,"p-M","transcriptional regulator of pyruvate dehydrogenase complex ","N.A.","988510 (N/A)","N.A.","N.A.","+",null,null,1104223,null,"+",112,"67-236 (M); 129-226 (L)",null,6.1,32115,"C",null,0,null,"N",null,"Regulatory functions","Other","GntR-like bacterial transcription factor"]
[134,"y0767","aceE",22124680,"NP_668103","Y","p-M","pyruvate dehydrogenase subunit E1 (dihycarboxylase component) ","13407502 (5%)","2594559 (161%)","2950138 (27%)","1537108 (59%)",{"v":0.016613190691685126,"d":"0.0166"},{"v":2.334151924747493,"d":"2.3342"},210834,5303017,1001380,679577,920,"33-885 (M); 33-885 (M); 33-874 (L); 46-885 (L) ",220,5.47,99838,"C",null,0,null,"N",null,"Energy metabolism","Pyruvate dehydrogenase","Membrane-associated pyruvate dehydrogenase complex "]
[91,"y0768","aceF",22124681,"NP_668104","Y","p-M","dihydrolipoamide acetyltransferase (pyruvate dehydrogenase complex)","4147298 (16%)","6774119 (33%)","N.A.","N.A.",{"v":0.042057123301314114,"d":"0.0421"},null,230464,8621260,"+",2262074,818,"126-483 (M); 126-505 (M); 59-505 (L); 86-492 (L)",1310,5.32,53972,"C",null,0,null,"N",null,"Energy metabolism","Pyruvate dehydrogenase","Membrane-associated pyruvate / 2-oxoglutarate dehydrogenase complex"]
[92,"y0769","lpdA",22124682,"NP_668105","Y","p-M","dihydrolipoamide dehydrogenase (pyruvate dehydrogenase complex)","10856523 (32.48%)","16694177 (24%)","2580566 (74%)","N.A.",{"v":0.04414839242034958,"d":"0.0441"},{"v":0.11503539283801327,"d":"0.1150"},2429844,22248224,756358,710146,776,"8-387 (M) incl. 8-25; 8-399 (L) incl. 8-25; 8-408 (M) incl. 8-25",null,5.74,50919,"C",null,0,null,"N",null,"Energy metabolism","Pyruvate dehydrogenase","Membrane-associated pyruvate / 2-oxoglutarate dehydrogenase complex"]
[223,"y0818","aph",22124731,"NP_668154","Y","p-M","sulfite reductase (NADPH), flavoprotein beta subunit ","1178247 (23%)","N.A.","434096 (50%)","843118 (57%)",{"v":0.0533360183330103,"d":"0.0533"},null,847851,"+",510180,1215290,448,"186-547 (M); 91-558 (L)",57,5.17,69032,"C",null,0,null,"N",null,"Central intermediary metabolism","Sulfur metabolism","Catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate"]
[120,"y0870","katY",22124781,"NP_668204"," ","p-M","catalase (hydroperoxidase HPI(I))  KatG/KatY","3428124 (53%)","5474346 (40%)","16563105 (42%)","2429053 (32%)",{"v":0.1795213749945266,"d":"0.1795"},{"v":3.3660475480052887,"d":"3.3660"},null,82148928,1137294,7005560,793,"43-735 (M); 43-749 (L); 59-745",null,7.17,83063,"U",null,0,null,"Y","38-39","Cellular processes","Detoxification","Enzyme secreted during oxidative stress, reported to be cell surface antigen in Y. pestis"]
[137,"y0914","clpB",22124822,"NP_668245",null,"p-M","protein disaggregation chaperone","N.A.","1488040 (81%)","483996 (74%)","140441 (25%)","+",{"v":0.4790990864836718,"d":"0.4791"},383602,1335226,455832,295667,1740,"97-788 (M); 78-788 (L); 1-788 (M) incl. 1-9; 69-788 (L); 17-788 (L) incl. 17-31 ",90,5.51,96430,"C",null,0,null,"N",null,"Protein fate","Degradation of proteins, peptides, and glycopeptides","Chaperone involved in heat shock response and protein turnover "]
[218,"y0964","frsA",22124871,"NP_668294",null,"p-M","hypothetical protein y0964 (putative fermentation/respiration switch protein)","1074267 (40%)","1203086 (51%)","N.A.","N.A.",{"v":0.0288360933297345,"d":"0.0288"},null,796692,844469,null,186227,154,"21-407 (L)",73,5.88,48008,"U",null,0,null,"N",null,"Hypothetical proteins","Conserved","Acetylesterase domain"]
[219,"y0966","proB",22124873,"NP_668296",null,"p-M","gamma-glutamyl kinase  ","N.A.","572986 (3%)","N.A.","126579 (37%)","+",{"v":0.5548466259859915,"d":"0.5548"},"+",660399,"+",442810,331,"2-217 (L) incl. 2-10; 2-336 (L) incl. 2-10",null,6.13,39381,"C",null,0,null,"N",null,"Amino acid biosynthesis","Glutamate family","Glutamate 5-kinase involved in proline biosynthesis"]
[66,"y0978","phoB",22124885,"NP_668308",null,"p-M","positive response regulator for pho regulon ","N.A.","N.A.","N.A.","826461 (15%)","+",{"$nulls":4},686237,224,"104-238 (L)",null,5.47,27502,"C  ",null,0,null,"N",null,"Regulatory functions","Other","Phosphorelay two-component signal transduction regulator of OmpR family, response regulator  "]
[null,"y1043","tesB",22124950,"NP_668373",null,"p-M","acyl-CoA thioesterase II ","1662504 (36%)","6640826 (21%)","N.A.","N.A.",{"v":0.10285167924029812,"d":"0.1029"},null,"+",null,null,"+",594,"17-292 (L) incl. 17-25",null,5.94,33431,"C",null,0,null,"N",null,"Unknown function","General","Hydrolyzes acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)"]
[140,"y1064","htpG",22124971,"NP_668394","Y","p-M","heat shock protein 90 ","2141870 (118%)","1559829 (42%)","1765969 (6%)","1751250 (62%)",{"v":0.08742672507702083,"d":"0.0874"},{"v":3.6623872619787923,"d":"3.6624"},1482424,2557761,842528,645819,1936,"52-616 (M); 52-616 (M); 202-624 (L); 10-624 incl. 10-16;  10-624 (L)",360,5.03,70987,"C",null,0,null,"N",null,"Protein fate","Protein folding and stabilization","Chaperone involved in heat shock response and protein turnover "]
[244,"y1194","(phoH1)",22125097,"NP_668520",null,"p-M","ATP-binding protein in pho regulon ","N.A.","2557103 (101%)","1691906 (12%)","N.A.","+",{"v":0.49239034845655516,"d":"0.4924"},null,"+","+",1243082,230,"84-357 (L);  18-370 (M) incl. 18-36; 18-370 (L) incl. 18-36",null,5.92,41907,"C",null,0,null,"N",null,"Unknown function","General","Phosphate starvation inducible protein PhoH with ATPase activity"]
[220,"y1195","(yleE)",22125098,"NP_668521",null,"p-M","hypothetical protein y1195 (putative iron-sulfur protein and methylthiolase)","N.A.","N.A.","N.A.","N.A.","+",null,"+","+",639866,"+",178,"182-498 (L)",null,5.41,58203,"U",null,0,null,"N",null,"Protein synthesis","tRNA and rRNA base modification","Enzyme involved in ribosomal structure and biogenesis"]
[313,"y1237","ureA",22125138,"NP_668561",null,"p-M","urease (urea amidohydrolase) gamma subunit","N.A.","4652864 (57%)","2396010 (51%)","N.A.",null,{"v":0.3832214329286921,"d":"0.3832"},"+",{"$nulls":3},199,"1-100 (L) incl. 1-6 and 11-22",null,5.35,11042,"U",null,0,null,"N",null,"Central intermediary metabolism","Other","With UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme"]
[94,"y1240","ureE",22125141,"NP_668564",null,"p-M","urease accessory protein UreE","N.A.","3077742 (7%)","2384423 (101%)","N.A.","+",{"v":0.5765442085728418,"d":"0.5765"},"+",9774462,1983692,1122108,248,"24-173 (M); 16-173 (L) incl. 16-21; 26-173 (L)",null,5.83,26405,"C",null,0,null,"N",null,"Central intermediary metabolism","Nitrogen metabolism","Involved in small molecule turnover "]
[291,"y1242","ureG",22125143,"NP_668566",null,"p-M","urease accessory protein UreG","N.A.","N.A.","699345 (45%)","N.A.","+",null,"+",null,833498,null,336,"25-220 (L)",null,4.88,24106,"C",null,0,null,"N",null,"Central intermediary metabolism","Nitrogen metabolism","Accessory protein for urease metalloenzyme involved in small molecule turnover"]
[278,"y1290","rpoE",22125190,"NP_667729",null,"p-M","RNA polymerase sigma factor RpoE ","N.A.","N.A.","1490702 (20%)","N.A.","+",null,null,"+",1084798,null,410,"17-191 (M); 2-191 (L) incl. 2-13",null,5.08,21860,"U",null,0,null,"N",null,"Transcription","Transcription factors","Member of the extracytoplasmic function sigma factors, global regulator"]
[68,"y1295","lepA",22125195,"NP_670791",null,"p-M","GTP-binding protein LepA ","N.A.","N.A.","N.A.","349826 (47%)","+",null,"+",null,null,544963,337,"24-501 (L); 56-482 (L)",null,5.57,67238,"C",null,0,null,"N",null,"Unknown function","General","Membrane-bound GTPase LepA "]
[" ","y1298","era",22125198,"NP_668621 ",null,"p-M","GTP-binding protein Era",{"$nulls":4},"+",{"$nulls":3},5034006,"+",78,"160-171 (L)",null,6.57,34565,"C",null,0,null,"N",null,"Cellular processes","Regulatory functions","RAS-like GTPase; binds the cell membrane through apparently via C-terminal domain"]
[82,"y1357","engA",22125256,"NP_668679",null,"p-M","GTP-binding protein EngA (putative ferrous iron uptake family protein)","N.A.","4872050 (127%)","3284242 (17%)","242765 (49%)","+",{"v":0.6268044085353499,"d":"0.6268"},{"$nulls":3},1135152,445,"27-472 (L); 27-482 (M); 1-482 (L); 1-472 (L) incl. 1-15",null,5.47,55029,"U",null,0,null,"N",null,"Unknown function","General","Predicted GTPase; gene locus near yfgL / yfgM; possibly involved in outer membrane biogenesis"]
[164,"y1362","guaB",22125261,"NP_668684","Y","p-M","inositol-5-monophosphate dehydrogenase  ","3158727 (94%)","15968995 (10%)","3594662 (118%)","935742 (43%)",{"v":0.17113619441125233,"d":"0.1711"},{"v":0.3146931302349218,"d":"0.3147"},633166,17577380,1019360,596074,325,"68-507 (M); 68-507 (L); 68-507 (L); 117-507 (L)",671,6.05,55310,"C",null,1,null,"N",null,"Purines, pyrimidines, nucleosides, and nucleotides","Purine ribonucleotide biosynthesis","Purine ribonucleotide biosynthesis"]
[163,"y1397","ppx",22125295,"NP_668718",null,"p-M","exopolyphosphatase","N.A.","4034422 (31%)","N.A.","485186 (28%)","+",{"v":0.30205236281043946,"d":"0.3021"},"+",6179076,"+",4866316,302,"31-451 (M); 31-460 (L); 31-451 (M); 31-460 (L)",205,5.89,58903,"U",null,0," ","N",null,"Central intermediary metabolism","Phosphorus compounds","Ppx/GppA phosphatase family"]
[314,"y1455","(ygiW)",22125352,"NP_668775",null,"p-M","putative outer membrane protein ","907051 (39%)","12399892 (13%)","3394034 (114%)","N.A.",{"v":0.42369617400052845,"d":"0.4237"},{"v":0.20369473735626462,"d":"0.2037"},"3889028*",null,null,"+",662,"69-131 (M); 69-131 (L)  ",null,7.82,14927,"U",null,0," ","Y","20-21","Fatty acid and phospholipid metabolism","Biosynthesis","Targeting of YgiW to the Sec-translocase for transport across the inner membrane is SecB-dependent "]
[95,"y1485","crr",22125383,"NP_668806",null,"p-M","glucose-specific PTS system enzyme IIA subunit  ","4867471 (51%)","4578101 (64%)","7182828 (30%)","N.A.",{"v":0.05249425725398249,"d":"0.0525"},{"v":1.1675933694108154,"d":"1.1676"},4499505,null,9013158,318741,485,null,null,4.8,18227,"C",null,0,null,"N",null,"Transport and binding proteins","Carbohydrates, organic alcohols, and acids","PEP-dependent phosphotransferase system, glucose-specific"]
[193,"y1579","fadI",22125474,"NP_668897",null,"p-M","3-ketoacyl-CoA thiolase  ",{"$nulls":4},"+",{"$nulls":3},506326,7380078,1021,"28-410 (L); 2-410 (M) incl. 2-11; 28-411 (L); 15-411 (L) incl. 15-22 ",67,6.68,46396,"C",null,0,null,"N",null,"Fatty acid and phospholipid metabolism","Degradation","Thiolase domain"]
[165,"y1601","accD",22125496,"NP_668919",null,"p-M","acetyl-CoA carboxylase beta subunit  ",{"$nulls":4},"+",null,null,5212780,null,"+",105,"155-292 (L); 70-356 (L); 81-316 (M); 221-292 (L)",241,8.48,39483,"U",null,0,null,"N",null,"Fatty acid and phospholipid metabolism","Biosynthesis","Possibly membrane-associated acetyl-CoA carboxylase complex  "]
[null,"y1611","(yfcH)",22125506,"NP_668929 ",null,"p-M","putative sugar nucleotide epimerase ","N.A.","3334275 (86%)","N.A.","N.A.",{"$nulls":5},"+",633,"78-296 (L); 5-296 (M) incl. 5-16",null,5.7,33852,"U",null,0,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","Has conserved S-adenosyl-L-homocysteine hydrolase and NAD dependent epimerase domains"]
[null,"y1631","nuoB",22125526,"NP_668949",null,"p-M","NADH dehydrogenase subunit B","N.A.","4786947 (12%)","2135580 (76%)","361748 (90%)","+",{"v":0.5218033977193242,"d":"0.5218"},"+",{"$nulls":3},96,"17-199 (M) incl. 17-36",null,5.76,25880,"U",null,0,null,"N",null,"Energy metabolism","Fermentation, Electron transport","Membrane-associated NADH dehydrogenase complex involved in aerobic respiration"]
[71,"y1632","nuoC",22125527,"NP_668847","Y","p-M","binfunctional NADH:ubiquinone oxidoreductase subunit C/D ","N.A.","11162062 (58%)","4883208 (13%)","1364857 (28%)","+",{"v":0.632681325909721,"d":"0.6327"},null,1008084,1178248,841810,654,"18-575 (M); 2-575 (L) incl. 2-17; 18-575 (M) incl. 18-31; 2-575 (L) ",null,5.83,69070,"C",null,0,null,"N",null,"Energy metabolism","Aerobic","Membrane-associated NADH dehydrogenase complex "]
[97,"y1633","nuoE",22125528,"NP_668951",null,"p-M","NADH dehydrogenase subunit E",null,"4286154 (71%)","2402219 (46%)","N.A.","+",{"v":0.417086707678986,"d":"0.4171"},"+",8023272,1248846,null,128,"48-160 (M)",null,5,20920,"C",null,0,null,"N",null,"Energy metabolism","Aerobic","Membrane-associated ATP synthase complex, NADH ubiquinone oxidoreductase "]
[251,"y1634","nuoF",22125529,"NP_668952",null,"p-M","NADH dehydrogenase I chain F ","N.A.","2902466 (21%)","1377694 (40%)","314797 (58%)","+",{"v":0.6256450829726685,"d":"0.6256"},424587,1270482,1082692,3424020,187,"51-458 (L); 51-458 (L); 14-447 (M) incl. 14-23",null,6.3,50934,"C",null,0,null,"N",null,"Energy metabolism","Aerobic","Membrane-associated ATP synthase complex, NADH ubiquinone oxidoreductase "]
[83,"y1635","nuoG",22125530,"NP_668848","Y","p-M","NADH dehydrogenase subunit G","N.A.","6685547 (48%)","3139306 (20%)","570176 (53%)","+",{"v":0.5636483707942828,"d":"0.5636"},"+","+","+",699011,300,"52-783 (M); 2-840 (L) incl. 2-9; 163-783 (M)",null,5.72,101584,"U",null,0,null,"N",null,"Energy metabolism","Aerobic","Membrane-associated NADH dehydrogenase complex involved in aerobic respiration; iron-sulfur cluster protein"]
[277,"y1637","nuoI",22125532,"NP_668849",null,"p-M","NADH dehydrogenase subunit I","N.A.","5173836 (21%)","1325729 (36%)","N.A.","+",{"v":0.19068811289260312,"d":"0.1907"},null,null,858752,334128,122,"5-43 (L) incl. 5-15; 5-176 (L) incl. 5-15 ",null,5.55,21058,"C",null,0,null,"N",null,"Energy metabolism","Electron transport","Membrane-associated NADH dehydrogenase complex "]
[124,"y1677","dps",22125572,"NP_668995",null,"p-M","DNA protection during starvation conditions  ","6047163 (42%)","15818058(57%)","4234078 (13%)","N.A.",{"v":0.0807690064424242,"d":"0.0808"},{"v":0.1991990273042279,"d":"0.1992"},909540,4631859,2605502,3963818,503,"9-153 (M) incl. 9-18; 19-153 (L); 9-153 (L) incl. 9-18 ",80,5.87,18859,"U",null,0,null,"N",null,"Regulatory functions","Other","DNA-binding dodecameric ferritin-like protein with oxidative protectant functions"]
[72,"y1794","phoP",22125688,"NP_669111",null,"p-M","DNA response regulator in two-comp. regulatory system with PhoQ ","N.A.","1719745 (35%)","1368975 (77%)","458661 (25%)","+",{"v":1.2622556602665609,"d":"1.2623"},649156,null,929970,748436,464,"3-214 (M) incl. 3-13; 3-314 (L) incl. 3-13",null,5.51,25625,"C",null,0,null,"N",null,"Energy metabolism","Photosynthesis","PhoP response regulator"]
[205,"y1845","-",22125738,"NP_669161","Y","p-M","probable N-acetylmuramoyl-L-alanine amidase  ","10944608 (44%)","7063160 (39%)","16426680 (34%)","1176008 (279%)",{"v":0.052325468296548924,"d":"0.0523"},{"v":2.1489249228588245,"d":"2.1489"},722972,1183899,12266594,4086598,353,"1-222 (M) incl. 1-10; 1-222 (L) incl. 1-10; 1-222 (M); 1-222 (L)",96,5.52,28780,"C",null,0,null,"N",null,"Cellular processes","Toxin production and resistance","Domain found in a variety of enzymes involved in bacterial cell wall degradation"]
[" ","y1935","sufB",22125827,"NP_669250","Y","p-M","cysteine desulfurase activator complex subunit SufB ",{"$nulls":4},"+",null,425340,1092748,null,null,124,"384-447 (L)",63,4.77,55548,"U",null,0,null,"N",null,"Unknown function","General","Complex with SufCD and activates cysteine desulfurase SufS"]
[292,"y1936","sufC",22125828,"NP_669251",null,"p-M","cysteine desulfurase ATPase component","N.A.","N.A.","593951 (32%)","N.A.","+",null,"+","+",418470,"+",164,"50-232 (M); 18-257 (L)",null,5.25,28618,"MSL",null,0,null,"N",null,"Transport and binding proteins","Unknown substrate","Part of the SUF system incorporating iron sulfur clusters in proteins"]
[98,"y1980","pspA",22125872,"NP_668857",null,"p-M","phage shock protein A  ","N.A.","6229531 (11%)","1166623 (56%)","N.A.","+",{"v":0.13936595839069346,"d":"0.1394"},null,1055386,522632,null,653,"7-214 (L) incl. 7-21 ",null,5.77,25386,"C",null,0,null,"N",null,"Mobile and extrachromosomal element functions","Prophage functions","Suppresses Sigma54-dependent transcription, peripheral membrane protein"]
[99,"y2023","adhE",22125915,"NP_669338","Y","p-M","CoA-linked acetaldehyde dehydrogenase  ","N.A.","11982997 (84%)","6494037 (37%)","495641 (37%)","+",{"v":0.5071884344435782,"d":"0.5072"},403788,774361,838010,212744,922,"2-884 (M) incl. 2-15; 2-865 (M) incl. 2-15; 2-884 (L) incl. 2-15 (L); 2-884 (L)",171,6.39,97040,"C",null,0,null,"N",null,"Energy metabolism","Fermentation","Iron-dependent alcohol dehydrogenase domain"]
[143,"y2168","(yeaG)",22126056,"NP_669479",null,"p-M","hypothetical protein y2168 (putative Ser protein kinase)","2071681 (39%)","1128533 (97%)","3297445 (23%)","1983355 (62%)",{"v":0.10643891816893516,"d":"0.1064"},{"v":6.588520074806316,"d":"6.5885"},2417832,null,2241964,4314412,651,"1-619 (M) incl. 1-8; 1-639 (L) incl. 1-8 ",null,5.66,74433,"C",null,0,null,"N",null,"Hypothetical proteins","Conserved","Putative serine protein kinase involved in signal transduction mechanisms "]
[177,"y2295","prsA",22126180,"NP_669603",null,"p-M","ribose-phosphate pyrophosphokinase  ","6810281 (13%)","5276945 (42%)","1161128 (17%)","N.A.",{"v":0.02321821866280902,"d":"0.0232"},{"v":0.163749149520026,"d":"0.1637"},478046,6884386,1100852,844958,486,"12-268 (M) incl. 12-24; 112-321 (L); 12-268 (L) incl. 12-24 ",null,5.26,35118,"C",null,0,null,"N",null,"Purines, pyrimidines, nucleosides, and nucleotides","Purine ribonucleotide biosynthesis","Catalyzes formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate/ATP"]
[214,"y2402","ybtT",22126286,"NP_669709",null,"p-M","yersiniabactin thioesterase ","N.A.","N.A.","860774 (99%)","479200 (69%)","+",null,1378272,null,1864280,1610217,232,"9-197 (L) incl. 9-16; 11-197 (L) incl. 11-16; 9-211 (M) incl. 9-16; ",229,5.68,24794,"U",null,0,null,"N",null,"Unclassified","Role category not yet assigned","Secondary metabolite (yersiniabactin) biosynthesis; release of polyketide chain and lactone formation"]
[75,"y2455","putA",22126338,"NP_668618","Y","p-M","proline dehydrogenase, P5C dehydrogenase ","N.A.","4273115 (66%)","2108996 (75%)","186782 (50%)","+",{"v":0.4770787304038782,"d":"0.4771"},"<50",813187,1715340,332298,889,"183-1242 (L); 94-1299 (L); 94-1299 (L); 320-1299 (M); 982-1299 (M)",481,5.76,145005,"C",null,0,null,"N",null,"Energy metabolism","Amino acids and amines","Flavoprotein; transcriptional repressor and proline-metabolic enzyme with FAD domain regulating"]
[101,"y2551","manX",22126432,"NP_669855","Y","p-M","mannose-specific PTS enzyme IIAB","929174 (18%)","27619698 (100%)","17829136 (42%)","901745 (159%)",{"v":1.1958131186221683,"d":"1.1958"},{"v":0.5623900065646947,"d":"0.5624"},981186,10767254,9890992,3631766,1253,"53-321 (L); 136-294 (M); 49-294 (M); 2-321 (L) incl. 2-19; 2-324 (L) incl. 2-19",220,5.58,35165,"C",null,0,null,"N",null,"Transport and binding proteins","Carbohydrates, organic alcohols, and acids","Membrane-associated PEP-dependent phosphotransferase system, glucose / maltose / N-acetylglucosamine-specific"]
[156,"y2739","(lonB)",22126616,"NP_670039","Y","p-M","ATP-dependent protease (Lon protease family)","N.A.","2395596 (49%)","1278527 (28%)","N.A.","+",{"v":0.39717128993718986,"d":"0.3972"},"+",null,1194244,321774,157,"18-461 (M); 165-575 (M); 176-574 (L)",null,4.74,66259,"U",null,0,null,"N",null,"Protein fate","Degradation of proteins, peptides, and glycopeptides","Serine protease with putative chaperone function  "]
[102,"y2766","mukE",22126644,"NP_670067",null,"p-M","condesin subunit E ","N.A.","1624255 (48%)","2990187 (123%)","N.A.","+",{"v":1.3700160638941947,"d":"1.3700"},"+",4462550,null,null,74,"70-195 (L); 95-201 (L)",null,4.88,28863,"C",null,0,null,"N",null,"Unknown function","General","Membrane-associated condesin complex with functions in chromosome partitioning / cell division"]
[77,"y2809","clpA",22126686,"NP_670109","Y","p-M","ATP-binding component of serine protease with AAA-type ATPase (F)","N.A.","701035 (107%)","621980 (64%)","838320 (16%)","+",{"v":3.663749661837207,"d":"3.6637"},"+",null,276894,384469,671,"79-752 (M); 79-752 (M); 93-752 (L); 79-752 (L)",144,5.78,84751,"C",null,0,null,"N",null,"Protein fate","Degradation of proteins, peptides, and glycopeptides","Involved in protein turnover; chaperone activity"]
[182,"y3065","sucC",22126941,"NP_670364","Y","p-M","succinyl-CoA synthetase subunit beta ","19487776 (5%)","3015432 (46%)","1518575 (100%)","N.A.",{"v":0.005477346568126193,"d":"0.0055"},{"v":0.37477294317411086,"d":"0.3748"},null,3977444,1153358,"+",181,"1-359 (L) incl. 1-9; 15-359 (M) incl. 15-29 ",136,5.27,41665,"C",null,0,null,"N",null,"Energy metabolism","TCA cycle","Catalyzes the interconversion of succinyl-CoA and succinate"]
[104,"y3066","sucB",22126942,"NP_670365","Y","p-M","dihydrolipoamide acetyltransferase (subunit of 2-oxoglutarate DH complex) ","14473042 (10%)","11562333 (20%)","728738 (33%)","716516 (33%)",{"v":0.024736622021899603,"d":"0.0247"},{"v":0.2025489347658591,"d":"0.2025"},1312306,16281494,726530,465548,296,"77-394 (M); 77-394 (M); 102-402 (L)",269,5.48,44286,"C",null,0,null,"N",null,"Energy metabolism","TCA cycle","Membrane-associated pyruvate / 2-oxoglutarate dehydrogenase complex"]
[222,"y3068","sdhB",22126944,"NP_670367",null,"p-M","succinate dehydrogenase iron-sulfur subunit  ","N.A.","2297158 (29%)","7868831 (48%)","N.A.","+",{"v":2.5491821775246373,"d":"2.5492"},null,"+",3379284,null,735,"1-236 (L) incl. 1-9; 1-205 (M) incl. 1-9",null,6.87,27264,"U",null,0,null,"N",null,"Energy metabolism","TCA cycle","Membrane-associated succinate dehydrogenase enzmye complex ; SdhC/D are integral membrane components   "]
[150,"y3069","sdhA",22126945,"NP_670368","Y","p-M","succinate dehydrogenase flavoprotein subunit  ","1634535 (40%)","5889331 (87%)","1755320 (68%)","1105159 (113%)",{"v":0.15707690053548348,"d":"0.1571"},{"v":0.6931233508881235,"d":"0.6931"},1502810,3386878,4496868,1966878,1424,"7-510 (M) incl. 7-21; 1-584 (L); 1-584 (L) incl. 1-6 and 7-21",null,5.68,64834,"MSL  ",null,0,"OM-LP","N",null,"Energy metabolism","TCA cycle","Membrane-associated succinate dehydrogenase enzmye complex ; SdhC/D are integral membrane components"]
[166,"y3123","lpxA",22126999,"NP_670422",null,"p-M","UDP-N-acetylglucosamine acyltransferase ","N.A.","1720484 (8%)","N.A.","N.A.","+",null,"+",5677125,null,null,183,"92-255 (M); 56-255 (M); 46-255 (L)",null,6.36,28499,"C",null,0,null,"N",null,"Cell envelope","Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides","Enzyme in lipid A biosynthesis pathway; lipopolysaccharide biosnthesis"]
[316,"y3124","fabZ",22127000,"NP_670423",null,"p-M","(3R)-hydroxymyristoyl ACP dehydratase ","3306757 (34%)","6002873 (49%)","959317 (46%)","N.A.",{"v":0.052301126320701,"d":"0.0523"},{"v":0.1189281075214144,"d":"0.1189"},{"$nulls":4},473,"29-147 (L); 21-100 (M)  ",null,6.1,19732,"C",null,0,null,"N",null,"Transcription","Degradation of RNA","Essential for membrane formation, primary dehydratase involved in unsaturated branch of fatty acid synthesis pathway"]
[265,"y3126","ompH",22127002,"NP_670425"," ","p-M","periplasmic chaperone (automembrane protein H) ",{"$nulls":4},"+",null,"16730058*",null,null,35541052,159,"57-185 (M); 78-161 (L) ; 87-193 (L)",120,9.47,21630,"OM",0,0,null,"Y","54-55","Cell envelope","Other","Involved in folding of and OM targeting outer membrane proteins"]
[null,"y3219","agaV",22127095,"NP_670518",null,"p-M","PTS family enzyme IIB component 2 (EIIB-AGA) ",{"$nulls":4},"+",{"$nulls":4},"+",78,"55-64 (L)",null,6.96,18213,"C",null,0,null,"N",null,"Central intermediary metabolism","Amino sugars","Membrane-associated PEP-dependent phosphotransferase system, N-acetylgalactosamine-specific"]
[202,"y3295","visC",22127171,"NP_668888",null,"p-M","hypothetical protein y3295 (putative octaprenyl methoxyphenyl hydrolase)",{"$nulls":4},"+",null,"+","+","+",2829482,226,"125-331 (L); 429 (L); 125-429 (L)",null,7.8,53425,"IM",null,0,null,"N",null,"Unknown function","General","Predicted oxidoreductase with NAD/FAD(P)-binding domain"]
[312,"y3555","aspC",22127429,"NP_670852",null,"p-M","aspartate aminotransferase  ","6062711 (92%)","1509254 (159%)","8316679 (85%)","N.A.",{"v":0.03269536431972094,"d":"0.0327"},{"v":4.100805076624796,"d":"4.1008"},"+",null,null,"+",959,"8-403 (M) incl. 8-24; 1-403 (L) incl. 1-5 and 8-24",null,5.13,45665,"C",null,0,null,"N",null,"Energy metabolism","Amino acids and amines","Multifunctional enzyme that catalyzes synthesis of Asp, Phe and other compounds via a transamination reaction"]
[246,"y3590","-",22127464,"NP_670887",null,"p-M","enzyme (predicted methyltransferase)","N.A.","1242598 (24%)","N.A.","N.A.","+",null,"+",787298,"+",1855574,201,"119-396 (M); 119-351 (M); 119-396 (L); 111-396 (L)",145,5.43,44400,"C",null,0,null,"N",null,"Amino acid biosynthesis/ Biosynthesis of cofactors, prosthetic groups, and carriers/ Purines, pyrimidines, nucleosides, and nucleotides/ Central intermediary metabolism/ DNA metabolism/ Protein synthesis","Serine family/ Heme, porphyrin, and cobalamin/ DNA replication, recombination, and repair/ tRNA and rRNA base modification/ Restriction/modification","16R RNA methyltransferase (RsmC-like)"]
[175,"y3609","-",22127483,"NP_668903",null,"p-M","hypothetical protein y3609 (putative inner membrane protein)","N.A.","21699190 (64%)","18005744 (47%)","7422071 (27%)","+",{"v":1.4766036931804025,"d":"1.4766"},null,5674343,4461864,5488140,166,"2-66 (L) incl. 2-11 and 16-33; 16-66 (L); 16-51 (M) incl. 2-11 and 16-33",131,6.1,10991,"C",null,1,null,"N",null,"Cell envelope","Other","Membrane protein of unknown function"]
[44,"y3617","secA",22127491,"NP_670914","Y","p-M","preprotein translocase subunit SecA of Sec membrane complex ","371934 (29%)","4367850 (31%)","3527133 (32%)","4081807 (48%)",{"v":1.1938261308288907,"d":"1.1938"},{"v":2.948091975430411,"d":"2.9481"},740086,3469513,1001380,409360,1149,"24-880 (L); 9-880 (L) incl. 9-13; 9-880 (L); 125-844 (M)",193,5.29,102788,"IM",null,0,null,"N",null,"Protein fate","Protein and peptide secretion and trafficking","Subunit A of preprotein translocase  "]
[45,"y3621","ftsZ",22127495,"NP_670918","Y","p-M","cell division protein FtsZ ","N.A.","474918 (N/A)","1399267 (19%)","726001 (23%)","+",{"v":6.032113646644704,"d":"6.0321"},486855,629853,3519834,1530666,912,"15-356 (M) incl. 15-31; 15-338 (M); 1-356 (L) incl. 1-14 and 15-31; 1-356 (L) ",162,4.75,40400,"IM",null,0,null,"N",null,"Cellular processes","Cell division","Forms core of septial ring-shaped polymers at sites of cell division (Z-ring)"]
[null,"y3657","-",22127531,"NP_670954 ",null,"p-M","hypothetical protein y3657 ","N.A.","5712527 (26%)","2539540 (15%)","N.A.",null,{"v":0.3308326127050497,"d":"0.3308"},{"$nulls":4},194,"15-110 (L) incl. 15-33",null,5.1,13489,"U",null,0,null,"N",null,"Hypothetical proteins","Conserved","Poly(A) polymerase and peptidylprolyl cis- trans isomerase domains"]
[78,"y3669","(clpB2)",22127543,"NP_668894","Y","p-M","ATP-dependent protease associated with type VI secretion system","N.A.","1232613 (17%)","1713907 (56%)","1575905 (76%)","+",{"v":4.24590090414655,"d":"4.2459"},"+",null,1000232,3607418,552,"217-851 (M); 36-822 (M); 23-851 (L); 23-843 (L)",137,5.61,96900,"C",null,0,null,"N",null,"Protein fate","Degradation of proteins, peptides, and glycopeptides","Involved in protein turnover, post-translational modification"]
[167,"y3753","rsmC",22127624,"NP_671047",null,"p-M","16S ribosomal RNA m2G1207 methyltransferase ","N.A.","2153205 (29%)","N.A.","N.A.","+",null,null,2967921,null,"+",274,"14-341 (L) incl. 14-21",null,6.12,37947,"U",null,0,null,"N",null,"Amino acid biosynthesis/ Biosynthesis of cofactors, prosthetic groups, and carriers/ Central intermediary metabolism/ DNA metabolism/ Protein synthesis","Serine family/ Heme, porphyrin, and cobalamin/ DNA replication, recombination, and repair/ tRNA and rRNA base modification/ Restriction/modification","Ribosomal methyltransferase"]
[null,"y3773","(lsrF)",22127644,"NP_671067 ",null,"p-M","putative autoinducer-2 (AI-2) aldolase ","3216113 (90%)","4979133 (95%)","2230856 (108%)","351871 (119%)",{"v":0.060230437057642715,"d":"0.0602"},{"v":0.510920461500538,"d":"0.5109"},{"$nulls":4},1050,"2-275 (L) incl. 2-11 and 12-27; 12-291 (L) incl. 12-27",null,6.08,31819,"U",null,0,null,"N",null,"Amino acid biosynthesis","Aspartate family","Has conserved fructose-1,6-bisphosphate (FBP) aldolase domain"]
[107,"y3859","uspA",22127730,"NP_671153"," ","p-M","universal stress protein ","591833 (16%)","9729308 (31%)","21698737 (29%)","1410906 (89%)",{"v":1.2799954016806674,"d":"1.2800"},{"v":2.023943345821359,"d":"2.0239"},null,3093121,8273976,18847864,474,"2-140 (M) incl. 2-17; 2-148 (L) incl. 2-17 and 18-33; 2-140 (L); 2-22 (L)",null,4.77,16485,"C",null,0,null,"N",null,"Cellular processes","Adaptations to atypical conditions","Protein responding to stress"]
[79,"y3916","ompR",22127786,"NP_671209","Y","p-M","osmolarity response regulator OmpR","757148 (201%)","801568 (73%)","1662176 (59%)","1389395 (112%)",{"v":0.187998046498412,"d":"0.1880"},{"v":5.896706757081701,"d":"5.8967"},536365,2040752,1742222,1083552,548,"7-220 (M) incl. 7-15; 7-220 (L) incl. 7-15 and 7-32 ",null,6.16,27408,"C",null,0,null,"N",null,"Cell envelope","Other","Part of two-component regulatory system EnvZ / OmpR regulating outer membrane porins"]
[null,"y4101","ibpB",22127970,"NP_671393",null,"p-M","heat shock chaperone IbpB ","911165 (68%)","5691672 (48%)","4644796 (72%)","N.A.",{"v":0.2585197111114346,"d":"0.2585"},{"v":0.6073070219248444,"d":"0.6073"},{"$nulls":3},"+",400,"17-156 (M) incl. 17-25",null,5.23,19141,"U",null,0,null,"N",null,"Central intermediary metabolism","Nitrogen metabolism"," IbpA/IbpB, ClpB, and the DnaK system form a functional triade of chaperones"]
[80,"y4127","phoU",22127995,"NP_671418",null,"p-M","transcriptional regulator PhoU   ","N.A.","N.A.","N.A.","495209 (58%)","+",null,"+",null,"+",7106826,524,"9-240 (L) incl. 9-22; 9-232 (M) incl. 9-22; 61-240 (L); 9-184 (L)",null,5.4,27704,"C",null,0,null,"N",null,"Regulatory functions","Other","Persistence switch involved in tolerance to multiple antibiotics"]
[168,"y4133","glmU",22128001,"NP_671424",null,"p-M","GlcNAc-1-phosph. uridyltransferase/glucosamine-1-phosph. acetyltransferase ","625270 (57%)","1356335 (88%)","2024333 (102%)","314374 (43%)",{"v":0.1504053989993688,"d":"0.1504"},{"v":1.6928493946708818,"d":"1.6928"},893312,3692874,487818,2886614,285,"1-442 (L) incl. 1-17; 135-452 (M)",null,6.02,49282,"C",null,0,null,"N",null,"Cell envelope","Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides","Synthesis of metabolite leading to lipopolysaccharide and peptidoglycan biosynthesis"]
[109,"y4134","atpC",22128002,"NP_671425","Y","p-M","F0F1 ATP synthase subunit epsilon  ","N.A.","1663175 (41%)","5325448 (32%)","N.A.","+",{"v":2.3828665612597932,"d":"2.3829"},1302741,3280977,4277554,null,347,"2-125 (M) incl. 2-15 and 17-24; 2-125 (L) incl. 2-15 and 17-24 ",null,6.08,15107,"C",null,0,null,"N",null,"Energy metabolism","ATP-proton motive force interconversion","Membrane-associated ATP synthase complex, alpha-helix domain"]
[110,"y4135","atpD",22128003,"NP_671426","Y","p-M","F0F1 ATP synthase subunit beta  ","8781887 (19%)","77852018 (58%)","47189619 (30%)","5765448 (30%)",{"v":0.3736851155887834,"d":"0.3737"},{"v":0.6370870963553349,"d":"0.6371"},1754242,29831446,13304424,3901134,1623,"26-367 (M); 39-367 (M); 26-393 (L); 26-367 (L)",338,4.95,50210,"C",null,0,null,"N",null,"Energy metabolism","ATP-proton motive force interconversion","Membrane-associated ATP synthase complex, nucleotide-binding regulatory subunit"]
[293,"y4136","atpG",22128004,"NP_671427",null,"p-M","F0F1 ATP synthase subunit gamma ","N.A.","N.A.","694701 (N/A)","N.A.","+",null,"+",null,590052,"+",131,"65-200 (L); 155-267 (L)",null,8.99,31671,"U",null,0,null,"N",null,"Energy metabolism","ATP-proton motive force interconversion","Membrane-associated ATP synthase complex, regulatory subunit  "]
[127,"y4137","atpA",22128005,"NP_671428","Y","p-M","F0F1 ATP synthase subunit alpha  ","9053945 (13%)","65087905 (17%)","27804310 (16%)","5891841 (56%)",{"v":0.2860325032562724,"d":"0.2860"},{"v":0.5452578603344737,"d":"0.5453"},1013444,23485934,13912864,6494776,937,"60-418 (M); 1-499 (M) incl. 1-13; 1-508 (L) incl. 1-13 ",369,5.52,55337,"U",null,0,null,"N",null,"Energy metabolism","ATP-proton motive force interconversion","Membrane-associated ATP synthase complex, catalytic core subunit"]
[111,"y4138","atpH",22128006,"NP_671429",null,"p-M","F0F1 ATP synthase subunit delta ","N.A.","7714615 (110%)","3466606 (45%)","684927 (59%)","+",{"v":0.5573941902992371,"d":"0.5574"},56979,2844541,1688738,1087542,333,"2-165 (M) incl. 2-13 and 14-27; 14-177 (L) incl. 2-13 and 14-27; 14-177 (L)",null,5.31,19597,"C",null,0,null,"N",null,"Energy metabolism","ATP-proton motive force interconversion","Membrane-associated ATP synthase complex, catalytic core subunit"]
[112,"y4139","atpF",22128007,"NP_671430",null,"p-M","F0F1 ATP synthase subunit B  ","N.A.","3146701 (16%)","388290 (58%)","N.A.","+",{"v":0.0918295065212742,"d":"0.0918"},null,4804610,"+","+",320,"24-134 (M); 24-134 (M); 36-156 (L); 37-151 (L)",476,5.42,17304,"C",null,1,null,"N",null,"Energy metabolism","ATP-proton motive force interconversion","Membrane-associated ATP synthase complex, regulatory subunit  "]
[29,"YPKMT065","caf1",31795234,"NP_857692"," ","p-M","F1 capsule antigen  ",{"$nulls":4},"+",null,"+",3675224,"+","+",266,"45-170 (L); 123-145 (M)",null,4.83,17655,"OM",null,0,null,"Y","22-23","Cell envelope","Pathogenesis"," Yersinia pestis cell envelope capsule-forming protein "]
[" ","YPKMT089","parA",31795252,"NP_857708",null,"p-M","partitioning protein",{"$nulls":4},"+",null,437906,null,"+",1953590,161,"4-346 (M) incl. 4-14 and 15-24; 299-317 (L)",null,5.85,44929,"C",null,0,null,"Y","21-22","Unclassified","Role category not yet assigned","Similar to sequence encoding phage P7 ParA; putative ATPase involved in chromosome partitioning"]
[129,"y0294","hslU",22124212,"NP_667635",null,"p-M*","ATP-dependent protease ATP-binding subunit ","N.A.","N.A.","N.A.","269782 (63%)","+",null,6361699,1904693,"+",252191,349,"8-401 (L) incl. 8-22; 52-393 (L)",null,5.25,49887,"C",null,0,null,"N",null,"Protein fate","Protein folding and stabilization","Heat shock protein involved in degradation of misfolded proteins "]
[132,"y0609","groEL",22124523,"NP_667946","Y","p-M*","chaperonin GroEL ","38732927 (61%)","41959118 (85%)","10188052 (51%)","2321416 (33%)",{"v":0.03680930530577618,"d":"0.0368"},{"v":0.31965255677769994,"d":"0.3197"},15854342,62106044,7155266,1521212,1341,"19-468 (M) incl. 19-28; 19-548 (L) incl. 19-28; 19-468 (M); 19-548 (L)",2597,4.91,57509,"C",null,0,null,"N",null,"Protein fate","Protein folding and stabilization","Chaperone involved in heat shock response and protein turnover "]
[255,"y0651","fklB",22124565,"NP_667988"," ","p-M*","FKBP-type peptidyl-prolyl cis-trans isomerase  ","1980561 (12%)","1937079 (24%)","849035 (21%)","N.A.",{"v":0.0333975164425,"d":"0.0334"},{"v":0.32618184390001653,"d":"0.3262"},1738820,null,611338,2519200,155,"44-184 (L); 44-184 (M)",132,4.71,22412,"OM",null,0,null,"N",null,"Protein synthesis","Translation factors","Peptidyl-prolyl cis-trans isomerase involved in protein folding enriched in periplasm"]
[159,"y0687","nusA",22124601,"NP_668024","Y","p-M*","transcription elongation factor NusA  ","3035440 (42%)","5690008 (31%)","N.A.","N.A.",{"v":0.048266211166734345,"d":"0.0483"},null,866728,8842254,"+","+",346,"10-276 (L) incl. 10-22; 44-267 (M); 59-276 (M); 10-367 (L) incl. 10-22",67,4.52,55549,"C",null,0,null,"N",null,"Transcription","Transcription factors","Promotes RNA hairpin folding resulting in transcriptional termination"]
[310,"y0694","pnp",22124608,"NP_668031","Y","p-M*","polynucleotide phosphorylase/polyadenylase ","13310137 (13%)","7783717 (15%)","1344091 (50%)","N.A.",{"v":0.016992619805851015,"d":"0.0170"},{"v":0.12850592685241005,"d":"0.1285"},7694099,7970085,945086,335678,804,"82-737 (L); 82-690 (M);  82-707 (M)",240,5.33,79856,"C",null,0,null,"N",null,"Transcription","Transcription factors","RNA synthesis and modification"]
[114,"y0807","htrA",22124720,"NP_668143"," ","p-M*","periplasmic serine endoprotease Do ","1465216 (63%)","N.A.","N.A.","N.A.","+",null,"3103439*",30799152,"+","+",543,"48-471 (M); 48-292 (L)",null,8.81,49950,"P",null,1,null,"Y","28-29","Protein fate","Degradation of proteins, peptides, and glycopeptides","Serine protease with chaperone function involved in folding / degradation of periplasmic and outer membrane proteins"]
[115,"y0815","sodC",22124728,"NP_668151"," ","p-M*","periplasmic superoxide dismutase precursor (Cu-Zn)  ","N.A.","N.A.","1051025 (81%)","N.A.","+",null,"15054076*",22552686,1199676,"+",282,"47-188 (M); 47-188 (L)",null,7.85,20126,"P",null,0,null,"Y","20-21","Mobile and extrachromosomal element functions","Prophage functions","Detoxification enzyme in periplasm"]
[93,"y0988","ahpC",22124895,"NP_668318"," ","p-M*","peroxidase (putative alkyl hydroperoxide reductase subunit C)","35788044 (7%)","7170051 (59%)","3872500 (60%)","210655 (235%)",{"v":0.0076127342991944525,"d":"0.0076"},{"v":0.4757215034956468,"d":"0.4757"},906908,17835100,4565930,763190,501,"61-177 (M);  1-200 (L) incl. 1-6",268,5.7,22358,"C",null,0,null,"N",null,"Cellular processes","Detoxification","Putative thiol-alkyl hydroperoxide reductase with antioxidant activity"]
[121,"y1026","tig",22124933,"NP_668356",null,"p-M*","trigger factor  ","17472022 (7.63%)","707927 (25%)","1682852 (16%)","244603 (41%)",{"v":0.0037942353479782655,"d":"0.0038"},{"v":2.6368632608650593,"d":"2.6369"},3302067,17677180,1650178,3642542,568,"1-361 (L) incl. 1-13; 1-434 (M) incl. 1-13",124,4.85,48211,"U",null,0,null,"N",null,"Protein fate","Protein and peptide secretion and trafficking","Peptidyl-prolyl cis-trans isomerase involved in protein folding and stress response"]
[139,"y1029","lon",22124936,"NP_668359","Y","p-M*","DNA-binding ATP-dependent protease La (heat shock protein K) ","1468604 (126%)","1370487 (36%)","N.A.","815841 (54%)",{"v":0.059954190151364085,"d":"0.0600"},{"v":1.4951539294103589,"d":"1.4952"},951554,969695,"+",442861,881,"27-738 (L); 57-760 (L); 57-760 (M); 16-760 (M) incl. 16-26; 27-738 (L) ",66,5.86,89749,"C",null,0,null,"N",null,"Protein fate","Degradation of proteins, peptides, and glycopeptides","Protease with regulatory functions and involved in heat shock response  "]
[122,"y1239","ureC",22125140,"NP_668563"," ","p-M*","urease (urea amidohydrolase) alpha subunit  ","8239847 (20%)","9388539 (48%)","1195679 (74%)","422979 (55%)",{"v":0.03543832421416051,"d":"0.0354"},{"v":0.20793155232907842,"d":"0.2079"},9573468,6377500,933222,439008,567,"16-546 (M) incl. 16-27; 31-421 (M); 16-546 (L) incl. 16-27 ",175,5.41,58838,"U",null,0,null,"N",null,"Central intermediary metabolism","Nitrogen metabolism","Metalloenzyme involved in small molecule turnover, secreted during oxidative stress"]
[311,"y1363","guaA",22125262,"NP_668685",null,"p-M*","bifunctional GMP synthase/glutamine amidotransferase protein","2843063 (38%)","2128419 (21%)","N.A.","N.A.",{"v":0.019276253461148054,"d":"0.0193"},null,2286958,2838386,"+","+",557,"175-509 (M); 107-509 (L); 117-509 (L)",205,5.55,58841,"C",null,0,null,"N",null,"Purines, pyrimidines, nucleosides, and nucleotides","Purine ribonucleotide biosynthesis","Converts ATP, xanthosine 5'-phosphate, L-glutamine and water to AMP, biphosphate, GMP and L-glutamate"]
[154,"y1620","pta",22125515,"NP_668846",null,"p-M*","phosphate acetyltransferase ","627493 (136%)","233586 (176%)","N.A.","211556 (25%)",{"v":0.03138832734169586,"d":"0.0314"},{"v":2.274750856165918,"d":"2.2748"},null,1190450,null,186523,742,"31-681 (L); 45-691 (L)",103,5.22,77753,"U",null,0,null,"N",null,"Energy metabolism","Other","Fermentation, phosphate acetyltransferase activity"]
[144,"y2394","ybtS",22126278,"NP_669701",null,"p-M*","salicylate synthase Irp9  ","551076 (107%)","1277811 (65%)","2541256 (75%)","1842535 (41%)",{"v":0.364295302650801,"d":"0.3643"},{"v":5.101638334147499,"d":"5.1016"},774175,737269,2391462,2138322,1021,"26-416 (M); 26-434 (L); 51-434 (L)",136,5.66,48414,"C ",null,0,"OM-LP","N",null,"Unclassified","Role category not yet assigned","Enzyme involved in chorismate / yersiniabactin biosynthesis"]
[221,"y2399","irp2",22126283,"NP_669706",null,"p-M*","HMWP2 nonribosomal peptide synthetase  ",{"$nulls":4},"+",null,"+","+",428576,439008,393,"1344-1803 (L); 1369-1803 (L)",1413,5.78,230218,"MSL   ",null,0,null,"N",null,"Protein synthesis","tRNA aminoacylation","Secondary metabolite (yersiniabactin) biosynthesis; hydrophobic segments temporarily associate with IM "]
[155,"y2400","irp1",22126284,"NP_679707",null,"p-M*","HMWP1 nonribosomal peptide synthetase  ",{"$nulls":4},"+",null,154363,"+",1093816,71225,737,"138-2733 (L); 153-2091 (L); 138-2384 (L",2448,5.43,351658,"U",null,0,null,"N",null,"Cellular processes","Toxin production and resistance","Secondary metabolite (yersiniabactin) biosynthesis"]
[" ","y2401","ybtU",22126285,"NP_669708",null,"p-M*","thiazolinyl-S-HMWP1 reductase ",{"$nulls":4},"+",null,1603355,"+",2506890,19205108,483,"12-386 (L) incl. 12-28; 68-386 (M) ",134,6.39,43680,"U",null,0,null,"N",null,"Unclassified","Role category not yet assigned","Enzyme involved in chorismate / yersiniabactin biosynthesis"]
[145,"y2403","ybtE",22126287,"NP_669710",null,"p-M*","salicyl-AMP ligase ","987858 (16%)","N.A.","2006872 (21%)","524024 (111%)",{"v":0.07323320718244762,"d":"0.0732"},null,1003197,"+",1994002,342552,430,"31-458 (L); 87-519 (M); 87-482 (L)",390,5.32,57701,"C",null,0,null,"N",null,"Unclassified","Role category not yet assigned","Enzyme involved in chorismate / yersiniabactin biosynthesis"]
[116,"y3055","tolB",22126931,"NP_670354"," ","p-M*","periplasmic translocation protein TolB  ","N.A.","8547862 (66%)","3191870 (119%)","1093346 (98%)","+",{"v":0.5991467155015447,"d":"0.5991"},"20476816*",4979726,"+",1315936,796,"25-360; 68-422; 25-430; 25-422; 71-611 (L); 71-603 (M)",128,6.61,46016,"P",null,0,null,"Y","22-23","Transport and binding proteins","Other","Interacts with Pal during outer membrane invagination for cell division "]
[105,"y3067","kgd",22126943,"NP_670366","Y","p-M*","alpha-ketoglutarate decarboxylase (subunit of 2-oxoglutarate DH complex) ","4618423 (94%)","896481 (53%)","N.A.","177392 (31%)",{"v":0.007482013058917469,"d":"0.0075"},{"v":0.4969906754012842,"d":"0.4970"},3256981,919472,"+",161806,771,"188-902 (M); 43-902 (L) ",247,5.96,105614,"C",null,0,null,"N",null,"Energy metabolism","TCA cycle","Membrane-associated pyruvate / 2-oxoglutarate dehydrogenase complex"]
[304,"y3314","metK",22127190,"NP_670613 ","Y","p-M*","S-adenosylmethionine synthetase ","7193579 (6%)","465932 (42%)","3541651 (35%)","1753164 (101%)",{"v":0.02686274709892999,"d":"0.0269"},{"v":15.107232136279395,"d":"15.1072"},7194485,890009,1463180,6890280,414,"2-384 (L) incl. 2-18; 99-363 (M)",116,5.36,42221,"C",null,0,null,"N",null,"Central intermediary metabolism","Other","Catalyzes the formation of S-adenosylmethionine from methionine and ATP, methylation of cell division apparatus"]
[172,"y3673","-",22127547,"NP_670970","Y","p-M*","hypothetical protein y3673 (putative HCP subunit of type VI secretion system)","32077828 (23%)","1814020 (97%)","7862592 (44%)","1767582 (112%)",{"v":0.00971635102993097,"d":"0.0097"},{"v":5.672891993960222,"d":"5.6729"},874028,6005872,9473220,3805386,192,null,154,5.18,19000,"U",null,0,null,"N",null,"Unknown function","General","Putative hemolysin-co-regulated protein (HCP) associated with type VI secretion system"]
[157,"y3706","dnaK",22127580,"NP_671003","Y","p-M*","molecular chaperone DnaK  ","16902748 (12%)","2130087 (34%)","5640396 (55%)","511523 (70%)",{"v":0.011596133667123277,"d":"0.0116"},{"v":2.5737255998747783,"d":"2.5737"},14430456,7913092,1990622,1693404,1413,"35-633 (M); 57-620; 26-633; 4-633 (L) incl. 4-23",136,4.86,69040,"U",null,0,null,"N",null,"Protein fate","Protein folding and stabilization","Chaperone involved in heat shock response and protein export via TAT system"]
[148,"y3985","fusA",22127855,"NP_671278","Y","p-M*","GTP-binding protein chain elongation factor EF-G ","13917408 (58%)","3637891 (52%)","5563068 (20%)","4832350 (71%)",{"v":0.03684444797264404,"d":"0.0368"},{"v":4.474301923195176,"d":"4.4743"},1025780,6125516,1374984,1090612,1041,"30-669 (M); 12-694; 12-694; 10-700 (L) incl. 10-23; 30-669; 30-700",2600,5.29,77716,"C",null,0,null,"N",null,"Protein synthesis","Translation factors","Ribosome translocase"]
[108,"y3986","tufB",22127856,"NP_671279","Y","p-M*","elongation factor Tu ","51982603 (37%)","13055659 (13%)","27467806 (14%)","10333229 (28%)",{"v":0.0294473444772527,"d":"0.0294"},{"v":3.5535842563803004,"d":"3.5536"},5335614,9757538,14127600,3413908,1854,"9-391 (L) incl. 9-25; 9-334 (M) incl. 9-25; 9-391; 9-334; 26-391; 9-391 ",3226,5.17,43304,"C",null,0,null,"N",null,"Protein synthesis","Translation factors","Reported to associates with membranes or cell surface during cellular stress  "]
[160,"y4015","rpoA",22127885,"NP_671308","Y","p-M*","DNA-directed RNA polymerase alpha subunit ","12079822 (6%)","12064543 (29%)","4420366 (20%)","147030 (18%)",{"v":0.03351490381688487,"d":"0.0335"},{"v":0.3032737625318431,"d":"0.3033"},2005766,19858712,3710016,5795792,484,"1-284 (L) incl. 1-12; 1-310 (L) incl. 1-12",155,4.98,36714,"C",null,0,null,"N",null,"Transcription","DNA-dependent RNA polymerase","Subunit of RNA polymerase"]
[30,"YPKMT067","caf1M",31795236,"NP_857694"," ","p-M*","periplasmic chaperone for F1 capsule antigen ",{"$nulls":4},"+",null,"39801910*",9419818,null,2395472,503,"34-250 (M); 34-250 (L)",null,8.38,28847,"OM",null,0,null,"Y","24-25","Motility and secretion / Intracellular trafficking and secretion","Protein folding and stabilization","Capsular biogenesis, outer membrane fimbrial usher protein PapD"]
[158,"Y1069","ymt",31795399,"NP_857852","Y","p-M*","murine toxin  ","61404366 (18%)","10898641 (51%)","1143828 (15%)","557178 (246%)",{"v":0.005513849307687402,"d":"0.0055"},{"v":0.20650690771104313,"d":"0.2065"},5754524,20860072,3211484,2120680,646,"26-583 (L); 26-583 (M); 40-583;",64,5.6,67675,"U",null,0,null,"N",null,"Cellular processes","Toxin production and resistance","Virulence factor of Y. pestis with phospholipase D activity  "]
[215,"y0048","glpX",22123969,"NP_667392",null,"C/R","fructose 1,6-bisphosphatase II ",{"$nulls":4},"+",null,"+",null,"+",463889,470,"13-352 (L) incl. 13-16; 13-352 (L) incl. 13-16",null,5.94,40405,"U",null,0,null,"N",null,"Unknown function","General","Dimeric enzyme dependent on Mg(2+) or Mn(2+)"]
[185,"y0161","pyrB",22124081,"NP_667504",null,"C/R","aspartate carbamoyltransferase catalytic subunit  ","4840618 (14%)","1265451 (18%)","N.A.","423360 (68%)",{"v":0.012387351970792923,"d":"0.0124"},{"v":0.8402718008817999,"d":"0.8403"},3184161,7885414,null,3857726,829,"2-280 (L) incl. 2-8 and 9-18; 2-297 (M) incl. 2-8 and 9-18",null,5.69,34595,"C",null,0,null,"N",null,"Purines, pyrimidines, nucleosides, and nucleotides","Pyrimidine ribonucleotide biosynthesis","Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate "]
[192,"y0223","cspI",22124143,"NP_667566 "," ","C/R","cold shock-like protein  ",{"$nulls":4},"+",null,12968590,6523365,8562616,null,111,"49-60 (M); 49-60 (L);",null,7.9,11148,"C",null,0,null,"N",null,"Cellular processes","Adaptations to atypical conditions","Protein of unknown function"]
[151,"y0244","(ssuD)",22124164,"NP_667587",null,"C/R","alkanesulfonate monooxygenase ",{"$nulls":4},"+",null,"+","+",null,510754,333,"26-315 (M); 26-315 (L); 26-272 (L); 26-315 (L)",86,5.8,41579,"U",null,0,null,"N",null,"Unknown function","General","Monooxygenase component, second component is integral membrane protein "]
[239,"y0303","metL",22124220,"NP_667643",null,"C/R","bifunctional aspartate kinase II / homoserine dehydrogenase II ","N.A.","N.A.","N.A.","309687 (108%)","+",null,null,"+","+",169730,421,"1-806 incl. 1-13 (L); 1-695 incl. 1-13 (L); ",73,5.75,89593,"U",null,0,null,"N",null,"Amino acid biosynthesis","Aspartate family","Methionine biosynthesis "]
[161,"y0308","ppc",22124225,"NP_667648",null,"C/R","phosphoenolpyruvate carboxylase  ","4147298 (16%)","1108520 (97%)","N.A.","N.A.",{"v":0.006882247318355747,"d":"0.0069"},null,1625928,2983366,"+",663804,656,"213-699 (L); 264-626 (L); 213-699 M)",159,5.54,101067,"U",null,0,null,"N",null,"Energy metabolism","Other","Phosphoenolpyruvate carboxylase activity, linked to PTS system"]
[130,"y0345","ilvC",22124261,"NP_667684","Y","C/R","ketol-acid reductoisomerase  ","17751293 (7%)","N.A.","1666494 (34%)","451251 (55%)",{"v":0.0034428770097408826,"d":"0.0034"},null,7929718,3576030,1701004,252191,833,"2-477 (L) incl. 2-11 and 12-19; 2-492 (L)",76,5.35,54243,"C",null,0,null,"N",null,"Amino acid biosynthesis","Pyruvate family","Isoleucine / leucine biosynthesis "]
[194,"y0361","rho",22124276,"NP_667699",null,"C/R","transcription termination factor Rho ",{"$nulls":4},"+",null,"+","+",1666812,6615096,867,"67-417 (M); 1-418 incl. 1-7 (L);  31-417 (L); 67-417 (M); 31-379 (L)",131,7.12,46887,"C",null,0,null,"N",null,"Transcription","Transcription factors","RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes"]
[240,"y0366","rffG",22124281,"NP_667704",null,"C/R","dTDP-glucose 4,6-dehydratase ",{"$nulls":4},"+",null,"+",null,null,124569,343,"6-352 (L) incl. 6-21 (L); 37-357 (L)",null,5.38,39966,"U",null,0,null,"N",null,"Cell envelope","Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides","Possibly involved in dTDP rhamnose/lipopolysaccharide biosynthesis"]
[241,"y0401","-",22124316,"NP_667739",null,"C/R","predicted hydrolase ","1906453 (15%)","N.A.","N.A.","274443 (51%)",{"v":0.009309649690203915,"d":"0.0093"},null,1558551,null,"+",966728,240,"78-312 (L); 78-199 (M); 78-310 (L); 78-312 (L); 97-270 (L)",null,5.88,36073,"C",null,0,null,"N",null,"Unknown function","General","Predicted hydrolase of HAD superfamily"]
[169,"y0483","rplL",22124398,"NP_667821",null,"C/R","50S ribosomal subunit protein L7/L12  ","21253356 (12%)","24745112 (42%)","2260949 (92%)","N.A.",{"v":0.03201721008540281,"d":"0.0320"},{"v":0.06799592168644937,"d":"0.0680"},5904096,41141292,1516002,812366,302,null,123,4.47,12523,"U",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","Ribosomal protein, 50S subunit"]
[308,"y0484","rpoB",22124399,"NP_667822 ","Y","C/R","DNA-directed RNA polymerase subunit beta","13281817 (9%)","3780100 (96%)","N.A.","1178960 (9%)",{"v":0.013068696544165887,"d":"0.0131"},{"v":0.7833414029283094,"d":"0.7833"},2745694,3911324,2527920,332253,779,"1-1328 (L) incl. 1-8; 38-1314 (L); 89-1262 (M); ",419,5.16,150751,"C",null,0,null,"N",null,"Transcription","DNA-directed RNA polymerase activity","Catalyzes transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates, catalytic core"]
[" ","y0485","rpoC",22124400,"NP_667823","Y","C/R","DNA-directed RNA polymerase subunit beta' ",{"$nulls":4},"+",null,621613,208939,null,"+",131,"996-1079 (M); 956-1152 (L)",1520,6.87,156989,"C",null,0,null,"N",null,"Transcription","Transcription factors","Catalyzes transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates, catalytic core"]
[242,"y0557","terB",22124471,"NP_667894",null,"C/R","tellurium resistance protein  ","N.A.","N.A.","N.A.","236456 (74%)","+",null,"+","+","+",193640,425,"81-136 (M); 9-136 (L) incl. 9-15 (L); 16-136 (L) incl. 16-24",null,5.27,16733,"C",null,0,null,"N",null,"Cellular processes","Adaptations to atypical conditions","Possibly involved in stress response, Colicin and tellurite resistance"]
[184,"y0638","(spoU)",22124552,"NP_667975",null,"C/R","23S rRNA (guanosine-2'-O-)-methyltransferase","N.A.","1569011 (42%)","N.A.","N.A.","+",null,null,2877093,null,"+",164,null,null,6.18,26876,"C",null,0,null,"N",null,"Protein synthesis","tRNA and rRNA base modification","Putative 23S rRNA guanosine 2'-O methyltransferase"]
[173,"y0645","rpsF",22124559,"NP_667982","Y","C/R","30S ribosomal protein S6  ","6603312 (9%)","6978952 (87%)","7862594 (41%)","2004925 (22%)",{"v":0.06966471835022829,"d":"0.0697"},{"v":1.5599560400446082,"d":"1.5600"},2362000,21510666,9473220,2041620,280,"3-130 (L) incl. 3-24; 25-130 (M); 39-130; 25-104",461,5.34,14998,"C",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","Ribosomal protein, 30S subunit"]
[176,"y0647","rplI",22124561,"NP_667984","Y","C/R","50S ribosomal protein L9 ","4865300 (72%)","15600062 (62%)","3857741 (24%)","N.A.",{"v":0.09775327908710973,"d":"0.0978"},{"v":0.18402984701316022,"d":"0.1840"},5741446,36278696,2722978,"+",611,null,213,6.3,15852,"C",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","Ribosomal protein, 50S subunit"]
[149,"y0668","mdh",22124582,"NP_668005"," ","C/R","malate dehydrogenase  ","12574772 (25%)","1942877 (76%)","1572496 (12%)","655127 (23%)",{"v":0.009743741575792785,"d":"0.0097"},{"v":1.4492244425196772,"d":"1.4492"},6730634,3227069,1782126,561018,331,"57-308 (L); 88-308 (L); 57-272 (M) ",144,5.53,32718,"MSL ",null,0,null,"Y","18-19","Energy metabolism","TCA cycle","Periplasmic protein in Y. pestis"]
[174,"y0672","rplU",22124586,"NP_668009",null,"C/R","50S ribosomal protein L21  ","N.A.","4692047 (10%)","N.A.","N.A.","+",null,null,5362995,null,"+",107,null,70,10.05,13576,"C",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","Ribosomal protein, 50S subunit"]
[133,"y0688","infB",22124602,"NP_668025","Y","C/R","translation initiation factor IF-2  ","N.A.","526615 (163%)","N.A.","145679 (26%)","+",{"v":0.6947987464475284,"d":"0.6948"},"+",868616,"+",742674,330,"8-874 (L) incl. 8-19; 8-858 (M) incl. 8-19; 209-874 (L); 382-874 (L) ",84,5.75,97793,"C",null,0,null,"N",null,"Protein synthesis","Translation factors","Enzyme associated with ribosome "]
[287,"y0689","rbfA",22124603,"NP_668026",null,"C/R","ribosome-binding factor A","N.A.","N.A.","1080320 (52%)","N.A.","+",null,"+","+",481092,"+",67,"36-101 (M); 50-139 (L); 36-139 (L)",null,7.93,17332,"C",null,0,null,"N",null,"Transcription","RNA processing","Associates with free 30S ribosomal subunits"]
[250,"y0784","panD",22124697,"NP_668120",null,"C/R","aspartate-alpha-decarboxylase ",{"$nulls":4},"+",null,2108646,2811953,null,2811953,111,"55-116 (L); 55-116 (M); 55-126 (L)",null,7.68,14125,"U",null,0,null,"N",null,"Biosynthesis of cofactors, prosthetic groups, and carriers","Pantothenate and coenzyme A","Pantothenate biosynthesis"]
[135,"y0785","panC",22124698,"NP_668121",null,"C/R","pantoate-beta-alanine ligase ","N.A.","N.A.","N.A.","484893 (41%)","+",null,584751,null,null,323701,367,"1-246 (L) incl. 1-11",null,5.46,31866,"C",null,0,null,"N",null,"Biosynthesis of cofactors, prosthetic groups, and carriers","Pantothenate and coenzyme A","Pantothenate cofactor biosynthesis"]
[136,"y0814","eno",22124727,"NP_668150",null,"C/R","phosphopyruvate hydratase (enolase)","21885084 (27%)","5921874 (44%)","12629328 (48%)","N.A.",{"v":0.01802499317893225,"d":"0.0180"},{"v":1.5870938278015718,"d":"1.5871"},1702456,11921870,2211178,520022,557,"11-426 (L) incl. 11-16; 17-419 (M) incl. 17-46; 11-419",279,5.18,45497,"C",null,0,null,"N",null,"Energy metabolism","Glycolysis/gluconeogenesis","Glycolytic enzyme reported as a cell surface membrane-associated protein "]
[64,"y0843","(deoR5)",22124754,"NP_668177",null,"C/R","transcriptional regulator  ","N.A.","N.A.","N.A.","131107 (38%)","+",null,"+","+",null,124632,410,"90-322 (L); 308-322 (L)",null,6.16,36769,"C",null,0,null,"N",null,"Regulatory functions","Other","Sugar-binding and Sigma factor-related domains "]
[216,"y0881","recA",22124791,"NP_668214","Y","C/R","recombinase A ","N.A.","N.A.","N.A.","1002904 (31%)","+",null,3008364,"+","+",709996,216,"74-311 (L);",132,5.12,38034,"U",null,0,null,"N",null,"DNA metabolism","DNA replication, recombination, and repair","Catalyses hydrolysis of ATP, SOS response"]
[null,"y0892","ffh",22124802,"NP_668225",null,"C/R","signal recognition particle protein (SRP54)",{"$nulls":4},"+",{"$nulls":3},"+","+",276,"235-453 (L); 22-453 (L)",84,9.6,49748,"C",null,0,null,"N",null,"Protein fate","Protein and peptide secretion and trafficking","Part of signal recognition particle complex; has signal peptide-binding domain"]
[217,"y0895","(rimM)",22124805,"NP_668228",null,"C/R","16S rRNA-processing protein  ","N.A.","820463 (6%)","N.A.","N.A.","+",null,401319,1013057,"+",null,372,null,null,4.8,21297,"C",null,0,null,"N",null,"Unknown function","General","Accessory protein needed for efficient assembly of 30S ribosome subunit"]
[65,"y0904","tyrA",22124813,"NP_668236",null,"C/R","bifunctional chorismate mutase/prephenate dehydrogenase ","N.A.","N.A.","N.A.","161422 (29%)","+",null,"+",null,null,237437,196,"1-362 (L) incl. 1-9",null,5.45,42339,"C",null,0,null,"N",null,"Amino acid biosynthesis","Aromatic amino acid family","Prephenate dehydrogenase and chorismate mutase "]
[138,"y0960","pepD",22124867,"NP_668290",null,"C/R","aminoacyl-histidine dipeptidase (peptidase D)  ","4391207 (27%)","2094387 (N/A)","357922 (60%)","408919 (17%)",{"v":0.01986487465671889,"d":"0.0199"},{"v":0.6175615730199615,"d":"0.6176"},293820,2473720,577184,297632,423,"50-333 (M); 50-389 (L) ",null,5.45,53187,"C",null,0,null,"N",null,"Protein fate","Degradation of proteins, peptides, and glycopeptides","Proteolytic enzyme "]
[null,"y1315","(yfhA)",22125215,"NP_668638",null,"C/R","predicted two-component transcriptional regulator ",{"$nulls":4},"+",{"$nulls":4},"+",202,"70-231 (L)",null,7.18,50714,"C",null,0,null,"N",null,"Regulatory functions","Other","Sigma-54 interacting regulator involved in membrane fusion and proteoplysis"]
[69,"y1331","suhB",22125230,"NP_668653",null,"C/R","suppressor protein ",{"$nulls":4},"+",null,9948941,3533706,null,"+",722,"14-267 (L) incl. 14-21",null,6.67,29251,"C",null,0,null,"N",null,"Fatty acid and phospholipid metabolism","Biosynthesis","Inositol-monophosphatase activity with global regulatory functions"]
[180,"y0769","upp",22125306,"NP_668729",null,"C/R","uracil phosphoribosyltransferase","1279146 (70%)","1481606 (73%)","675672 (32%)","N.A.",{"v":0.0399455143589392,"d":"0.0399"},{"v":0.3393788054439606,"d":"0.3394"},902875,3227069,509974,1159496,386,"81-178 (L); 24-278 (M); 14-178 (L) incl. 14-18 ",null,6.13,23957,"C",null,0,null,"N",null,"Energy metabolism","Pyruvate dehydrogenase","Salvage of nucleosides and nucleotides"]
[123,"y1417","bcp",22125315,"NP_668738",null,"C/R","thioredoxin-dependent thiol peroxidase","6056159 (10%)","1615536 (44%)","N.A.","N.A.",{"v":0.006868649507540032,"d":"0.0069"},null,5129577,3137125,null,"+",396,null,null,5.15,17787,"U",null,0,null,"N",null,"Unknown function","General","Detoxification enzyme with antioxidant functions "]
[96,"y1487","ptsI",22125384,"NP_668807",null,"C/R","PTS system phosphoenolpyruvate-protein phosphotransferase  ","7612236 (21%)","1314444 (50%)","2250476 (17%)","336403 (15%)",{"v":0.01296902280426528,"d":"0.0130"},{"v":1.9169260919445792,"d":"1.9169"},1996982,2353931,1659758,1461840,517,"1-559 (M) incl. 1-15 and 16-28 ; 1-559 (M) incl. 1-15 and 16-28; 16-559 (L)",61,4.83,63452,"C",null,0,null,"N",null,"Transport and binding proteins","Carbohydrates, organic alcohols, and acids","PEP-dependent phosphotransferase system "]
[178,"y1489","cysK",22125386,"NP_668809"," ","C/R","cysteine synthase A ","40753944 (7%)","6712286 (9%)","1161128 (17%)","984673 (199%)",{"v":0.006349322336657964,"d":"0.0063"},{"v":0.49718194991400333,"d":"0.4972"},4379392,7434669,5273656,1838636,909,null,413,5.25,34354,"U",null,0," ","N",null,"Amino acid biosynthesis","Serine family","Forms a complex with serine acetyltransferase CysE "]
[306,"y1507","-",22125404,"NP_668827  ","Y","C/R","aminotransferase","5705130 (22%)","3830276 (62%)","2733839 (21%)","511474 (40%)",{"v":0.03226677962729856,"d":"0.0323"},{"v":0.8665477916741057,"d":"0.8665"},4521157,2406999,1074384,2939740,413,null,75,6.81,46099,"C",null,0,null,"N",null,"Cellular processes","Other","Involvement in biological processes unknown"]
[null,"y1777","ndh",22125671,"NP_669094",null,"C/R","respiratory NADH dehydrogenase",{"$nulls":4},"+",null,"+",null,null,"+",279,"33-425 (L)",null,8.47,47436,"U",null,0,null,"N",null,"Energy metabolism","Aerobic","Membrane-associated NADH dehydrogenase complex, FAD-containing subunit"]
[142,"y1876","(kdgR)",22125769,"NP_669192",null,"C/R","regulator (predicted transcriptional regulator of IclR family)","1065336 (59%)","N.A.","N.A.","656636 (23%)",{"v":0.03986074124476273,"d":"0.0399"},null,657769,"+",null,649895,352,"9-259 (L) incl. 9-18; 9-259 (L); 31-259 (M); 31-259 (L)",null,5.5,29947,"C",null,0,null,"N",null,"Regulatory functions","Other","Transcriptional regulator possibly involved in isocitrate lyase metabolism "]
[245,"y1947","cfa",22125839,"NP_669262",null,"C/R","cyclopropane fatty acyl phospholipid synthase","N.A.","N.A.","N.A.","350973 (9%)","+",null,817413,1561714,null,"+",180,"111-342 (M); 144-342 (L); 144-244 (L)",null,6.32,44535,"C",null,0,null,"N",null,"Fatty acid and phospholipid metabolism","Biosynthesis","Phospholipid biosynthesis; outer membrane biogenesis"]
[269,"y1990","tpx",22125882,"NP_669305"," ","C/R","thiol peroxidase","21321984 (8%)","2722683 (35%)","4244911 (16%)","N.A.",{"v":0.00710274538022791,"d":"0.0071"},{"v":1.1602538873911217,"d":"1.1603"},8724638,2877855,3580090,498682,226,null,107,6.7,20848,"U",null,0,null,"N",null,"Cellular processes","Detoxification","Shows substrate specificity for alkyl hydroperoxides"]
[null,"y2067","(yciM)",22125957,"NP_669380",null,"C/R","hypothetical protein y2067 (predicted N-acetylglucosaminyl transferase)",{"$nulls":4},"+",{"$nulls":3},"+","+",377,"38-350 (L)",null,5.94,44764,"C",null,0,null,"Y","25-26","Unclassified","Role category not yet assigned","Putative N-acetylglucosaminyl-transferase with tetratricopeptide domain  "]
[267,"y2101 ","-",22125990,"NP_669413",null,"C/R","putative oxidoreductase","4147248 (14%)","N.A.","514669 (27%)","N.A.",{"v":0.0023779433875388773,"d":"0.0024"},null,4090209,509432,511286,2562442,304,null,null,5.61,38102,"C",null,0,null,"N",null,"Unknown function","General","Contains NAD-binding Rossmann fold"]
[null,"y2132","fnr",22126020,"NP_669443",null,"C/R","fumarate/nitrate reduction transcriptional regulator ",{"$nulls":4},"+",{"$nulls":4},"+",117,"146-227 (L)",null,7.68,28344,"C",null,0,null,"N",null,"Regulatory functions","Other","Catabolite gene activator, response regulator with sensory and DNA-binding domain"]
[null,"y2139","rstA",22126027,"NP_669450",null,"C/R","DNA-binding response regulator in two-comp. regulatory system w/ RstB ",{"$nulls":4},"+",{"$nulls":4},"+",104,"42-246 (L)",null,5.52,30316,"C",null,0,null,"N",null,"Regulatory functions","Other","Phosphorelay two-component signal transduction regulator of OmpR family regulon; sensor RstA  "]
[191,"y2165","gapA",22126053,"NP_669476"," ","C/R","glyceraldehyde-3-phosphate dehydrogenase ","32631860 (48%)","5510392 (96%)","3312020 (16%)","N.A.",{"v":0.00629287454645873,"d":"0.0063"},{"v":0.4472928731326995,"d":"0.4473"},10946136,15066548,1723074,418552,636,null,859,6.19,36105,"C",null,0," ","N",null,"Energy metabolism","Glycolysis/gluconeogenesis","Catalyzes formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate"]
[null,"y2175 ","(ycgB)",22126063,"NP_669486",null,"C/R","hypothetical protein y2175",{"$nulls":4},"+",{"$nulls":4},"+",149,"78-235 (L)",null,5.66,61140,"U",null,0,null,"N",null,"Unclassified","Role category not yet assigned","Putative sporulation protein"]
[null,"y2238","-",22126124,"NP_669547",null,"C/R","hypothetical protein y2238 (putative molecular chaperone)",{"$nulls":4},"+",null,"+",null,null,"+",149,"84-239 (L)",null,5.12,27129,"U",null,0,null,"N",null,"Unknown function","General","Putative metal-dependent glycoprotease and chaperone "]
[307,"y2244","zwf",22126130,"NP_669553","Y","C/R","glucose-6-phosphate 1-dehydrogenase","3380565 (65%)","570985 (53%)","918304 (66%)","367033 (39%)",{"v":0.01657548935212802,"d":"0.0166"},{"v":2.8113511718122357,"d":"2.8114"},1488951,1084658,437730,2164596,489,"18-476 (M) incl. 18-24; 64-529 (L)",153,5.97,60812,"C",null,0,null,"N",null,"Energy metabolism","Pentose phosphate pathway","Catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate"]
[null,"y2262","(cmoB)",22126148,"NP_669571",null,"C/R","enzyme (predicted S-adenoyl-L-methionine-dependent methyltransferase)",{"$nulls":4},"+",null,"+",null,null,"+",101,null,null,5.89,36714,"C",null,0,null,"N",null,"Unknown function","Enzymes of unknown specificity","S-adenosyl-methionine-dependent methyltransferase"]
[190,"y2290","prfA",22126175,"NP_669598",null,"C/R","peptide chain release factor 1  ","N.A.","541274 (23%)","N.A.","N.A.","+",null,"+",504562,"+",2085306,348,"41-336 (L); 41-328 M) ",null,5.07,40766,"C",null,0,null,"N",null,"Protein synthesis","Translation factors","Peptidyl-tRNA hydrolase"]
[100,"y2524","ftn",22126406,"NP_669829",null,"C/R","cytoplasmic ferritin  ","9158109 (55%)","3592727 (20%)","N.A.","N.A.",{"v":0.010101140084286796,"d":"0.0101"},null,5722432,5384532,null,"+",269,"72-193 (M); 72-193 (M); 72-206 (L); 173-206 (L)",81,5.62,23613,"C",null,1,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","Intracellular sequesteration of iron"]
[null,"y2751","(rlmL)",22126629,"NP_670052",null,"C/R","oxidoreductase ",{"$nulls":4},"+",{"$nulls":4},"+",127,"420-448 (L)",null,8.8,79736,"U",null,0,null,"N",null,"DNA metabolism","DNA replication, recombination, and repair","Predicted rRNA methyltransferase (E. coli)  "]
[283,"y2755","pyrD",22126632,"NP_670055",null,"C/R","dihydroorotate dehydrogenase ","N.A.","N.A.","1466100 (85%)","N.A.","+",null,"+","+",895640,"+",436,"103-305 (M); 103-336 (L)",77,8.24,37037,"C",null,0,null,"N",null,"Purines, pyrimidines, nucleosides, and nucleotides","Pyrimidine ribonucleotide biosynthesis","Catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway"]
[103,"y2781","rpsA",22126658,"NP_670081","Y","C/R","30S ribosomal protein S1  ","10782911 (50%)","24735783 (52%)","8171911 (20%)","2768268 (36%)",{"v":0.09019110087920183,"d":"0.0902"},{"v":0.5269403156684218,"d":"0.5269"},3571016,30511304,3759588,932028,1296,"15-450 (M) incl. 15-25; 15-552 (L) incl. 15-25; 44-479 (M); 34-552 (L) ",64,4.96,61362,"C",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","Binds mRNA to ribosome "]
[224,"y2821","poxB",22126698,"NP_670121",null,"C/R","pyruvate dehydrogenase  ","2262009 (30%)","N.A.","N.A.","161325 (113%)",{"v":0.004612269010413331,"d":"0.0046"},null,15956404,1786730,"+",2318436,182,null,null,5.8,62388,"C",null,0,null,"N",null,"Energy metabolism","Other","Putative enzyme in membrane-associated pyruvate dehydrogenase complex; thiamine pyrophosphate cofactor"]
[146,"y3119","accA",22126995,"NP_670418",null,"C/R","acetyl-CoA carboxylase carboxyltransferase subunit alpha ","1123459 (48%)","N.A.","1022987 (7%)","722625 (82%)",{"v":0.05904512833874966,"d":"0.0590"},null,770860,"+",884604,3250474,607,"28-277 (M); 32-287 (M); 19-287 (L) incl. 19-27; 2-287 (L) incl. 2-18 ",null,5.48,35644,"C",null,0,null,"N",null,"Fatty acid and phospholipid metabolism","Biosynthesis","Possibly membrane-associated acetyl-CoA carboxylase complex  "]
[147,"y3135","tsf",22127012,"NP_670435",null,"C/R","elongation factor Ts","13399480 (39%)","4443973 (15%)","3225995 (42%)","583797 (178%)",{"v":0.01597044524687874,"d":"0.0160"},{"v":0.8701720965283952,"d":"0.8702"},7147868,6483588,1958138,2567790,674,"56-269 (M); 56-283 (L); 88-283 (L) ",119,5.21,30816,"C",null,0,null,"N",null,"Protein synthesis","Translation factors","EF-Ts dimer associates with EF-Tu-GTP complex reactivating GTP"]
[171,"y3137","rpsB",22127013,"NP_670436",null,"C/R","30S ribosomal protein S2 ","N.A.","5636589 (157%)","1769642 (84%)","N.A.","+",{"v":0.23364181488501828,"d":"0.2336"},1170566,7785652,null,"+",111,null,156,7.78,30067,"C",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","Ribosomal protein, 30S subunit"]
[179,"y3307","fba",22127183,"NP_670606",null,"C/R","fructose-bisphosphate aldolase  ","24672946 (3%)","4488649 (38%)","2222726 (60%)","508534 (123%)",{"v":0.007743476512464762,"d":"0.0077"},{"v":0.6530628392786152,"d":"0.6531"},4882068,7751403,1705804,751146,428,null,74,5.71,39332,"U ",null,0,null,"N",null,"Energy metabolism","Glycolysis/gluconeogenesis","Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate"]
[162,"y3310","tktA",22127186,"NP_670609",null,"C/R","transketolase","14049576 (52%)","2804280 (71%)","1130567 (41%)","N.A.",{"v":0.006681309902696354,"d":"0.0067"},{"v":0.300024314992266,"d":"0.3000"},2600644,7621999,1021818,293562,1423,null,574,5.8,72113,"C",null,1,null,"N",null,"Energy metabolism","Pentose phosphate pathway","Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate"]
[303,"y3499","(yqhD)",22127373,"NP_670796",null,"C/R","oxidoreductase ","9816774 (5%)","N.A.","N.A.","N.A.","+",null,5985421,"+",1240437,"+",314,"1-365 (M) incl. 1-11; 32-340 (M); 32-375 (L)",null,5.72,42071,"C",null,0,null,"N",null,"Energy metabolism","Other","Fe- and NAD(P)-dependent alcohol dehydrogenase"]
[null,"y3524","(rfaE)",22127398,"NP_670821",null,"C/R","bifunct. heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase ",{"$nulls":4},"+",null,"+",null,null,"+",206,"118-386 (L); 48-386 (L)",66,5.53,52004,"C",null,0,null,"N",null,"Cell envelope","Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides","Possibly involved in biosynthesis of heptose precursor of LPS"]
[null,"y3529","cca",22127403,"NP_670826",null,"C/R","multifunct. tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase  ",{"$nulls":4},"+",null,null,"+",null,"+",157,"1-364 (L) incl. 1-11; 335-364 (L)",null,6.03,46488,"C",null,0,null,"N",null,"Protein synthesis","tRNA aminoacylation","2' nucleotidase involved in ribosomal structure and biogenesis, APT/CTP-binding domain"]
[null,"y3537","rpoD",22127411,"NP_670834",null,"C/R","RNA polymerase sigma factor RpoD",{"$nulls":4},"+",null,"+","+",null,"+",174,"260-597 (L); 122-603 (L)",null,4.74,72544,"C",null,0,null,"N",null,"Regulatory functions","Other","Involved in transcription initiation "]
[null,"y3630","murF",22127504,"NP_670826",null,"C/R","D-alanine:D-alanine-adding enzyme [Yersinia pestis KIM]",{"$nulls":4},"+",null,"+",null,"+","+",68,"107-450 (L); 442-450 (L)",null,5.39,48568,"C",null,0,null,"N",null,"Cell envelope","Biosynthesis and degradation of murein sacculus and peptidoglycan","UDP-N-acetylmuramyl pentapeptide synthase; inner membrane-associated peptidoglycan precursor biosynthesis"]
[187,"y3631","murE",22127505,"NP_670928",null,"C/R","UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase ","N.A.","1221502 (2%)","N.A.","N.A.","+",null,"+",885901,"+",null,412,"31-484 (M); 31-495 (L); 111-495 (L)",81,5.56,53057,"C",null,0,null,"N",null,"Cell envelope","Biosynthesis and degradation of murein sacculus and peptidoglycan","UDP-N-acetylmuramyl tripeptide synthase; inner membrane-associated peptidoglycan precursor biosynthesis"]
[126,"y3693","carA",22127567,"NP_670990",null,"C/R","carbamoyl-phosphate synthase small subunit  ","3403990 (6%)","N.A.","N.A.","N.A.","+",null,2055446,6215266,null,2953496,485,null,null,5.56,43757,"U",null,0,null,"N",null,"Purines, pyrimidines, nucleosides, and nucleotides","Pyrimidine ribonucleotide biosynthesis","Subunit of carbamoylphosphate synthase enzyme complex"]
[249,"y3697","lytB",22127571,"NP_670994",null,"C/R","4-hydroxy-3-methylbut-2-enyl diphosphate reductase ","N.A.","368966 (43%)","N.A.","N.A.","+",null,null,447771,null,null,276,"33-212 (M); 18-315 (L) incl. 18-32",null,5.31,35984,"C",null,0,null,"N",null,"Biosynthesis of cofactors, prosthetic groups, and carriers","Other","Isoprenoid biosynthesis, iron-sulfur cluster protein"]
[181,"y3804","glnA",22127675,"NP_671098",null,"C/R","glutamine synthetase  ","N.A.","4846996 (12%)","N.A.","N.A.","+",null,4246945,5351391,null,null,400,"35-455 (M); 37-455 (M); 57-434 (L); 111-434 (L)",null,5.16,52745,"C",null,0,null,"N",null,"Amino acid biosynthesis","Glutamate family","Forms glutamine from ammonia and glutamate and involved in assimilation of ammonia "]
[106,"y3858","gdhA",22127729,"NP_671152","Y","C/R","glutamate dehydrogenase ","5467134 (71%)","1784986 (91%)","N.A.","N.A.",{"v":0.008406729625663,"d":"0.0084"},null,3185888,14442134,"+","+",876,"18-448 (L) incl. 18-30; 18-437 (M) incl. 18-30; 55-391",336,6.61,48787,"C",null,0,null,"N",null,"Amino acid biosynthesis","Glutamate family","Glutamate metabolism"]
[" ","y3913","(yhgF)",22127783,"NP_671206",null,"C/R","hypothetical protein y3913",{"$nulls":4},"+",null,234935,"+",8145734,"+",483,"1-789 (L) incl. 1-7;  54-756 (M)",82,5.99,87464,"C",null,0,null,"N",null,"Unknown function","General","Similar to putative paral putative RNase R of Salmonella typhimurium; predicted transcriptional accessory protein"]
[" ","y3990","rplC",22127860,"NP_671283","Y","C/R","50S ribosomal protein L3",{"$nulls":4},"+",null,"+",13983818,5395988,6970722,164,null,270,9.91,22278,"U",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","Binds near the 3' end of the 23S rRNA"]
[" ","y4001","rplE",22127871,"NP_671294 ","Y","C/R","50S ribosomal protein L5 ",{"$nulls":4},"+",null,null,504562,"+",2085306,441,null,261,9.59,20308,"C",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","Part of 50S and 5S/L5/L18/L25 subcomplex"]
[]
["Part 2. Protein annotations, descriptions and mass spectrometry data pertaining to tryptic peptide analysis by 2D-LC-MS/MS experiments ab)"]
[" ","Locus tag","Gene name","Acc. no. gi|","Acc. no."," ","Category","Protein name and description"," "," "," "," "," "," "," "," "," "," "," "," ","MS  score","pI","Mr","P-SO RTb  ","BO ","TMHMM","Lipo-P","Signal-P ","Signal-P (HMM)","Main functional role (CMR)","Sub-role (CMR)","(Putative) protein motifs and functions"]
[{"$nulls":12}," ",{"$nulls":11},"MP"]
[]
[null,"y0046","glpF",22123967,"NP_667390.1",null,null,"facilitator for glycerol uptake",{"$nulls":12},121,5.52,29766,"CM",null,6,null,"N",null,"Transport and binding proteins","Other","Major intrinsic protein transporter family (MIP)"]
[null,"y0074","secB",22123995,"NP_667418.1",null,null,"protein export; molecular chaperone",{"$nulls":12},106,4.09,17793,"C",null,0,null,"N",null,"Protein fate","Protein and peptide secretion and trafficking","Sec secretion apparatus component"]
[null,"y0076","-",22123997,"NP_667420.1",null,null,"hypothetical protein y0076",{"$nulls":12},160,9.37,15916,"C",null,1,null,"N",null,"Unknown function","General","Putative Rhodanese-related sulfurtransferase in Salmonella typhimurium LT2"]
[null,"y0106","gltS",22124026,"NP_667449.1",null,null,"sodium/glutamate symporter",{"$nulls":12},222,8.23,42697,"CM",null,11,null,"N",null,"Transport and binding proteins","Amino acids, peptides and amines","Sodium ion / glutamate symporter family"]
[null,"y0134","rplM",22124054,"NP_667477.1",null,null,"50S ribosomal subunit protein L13",{"$nulls":12},85,9.91,16564,"C",null,0,null,"N",{"$nulls":3},"50S ribosome subunit"]
[null,"y0139","degS",22124059,"NP_667482.1",null,null,"serine endoprotease",{"$nulls":12},127,6.12,38349,"P",null,1,null,"Y","34-35","Protein fate","Degradation of proteins, peptides, and glycopeptides","Responses to unfolded protein stress in periplasmic space, inner membrane-bound"]
[null,"y0144","(yrbD)",22124064,"NP_667487.1",null,null,"ATP-binding protein of putative ABC superfamily transporter y0144",{"$nulls":12},287,5.33,20289,"U",null,1,null,"N",null,"Transport and binding proteins","Unknown substrate","ABC transporter binding protein for toluene tolerance"]
[null,"y0166","treB",22124086,"NP_667509.1",null,null,"PTS system enzyme IIBC",{"$nulls":12},63,9.01,52713,"CM",null,11,null,"N",{"$nulls":3},"Glucose/maltose/N-acetylglucosamine-specific transporter of PEP-PTS system "]
[null,"y0195","-",22124115,"NP_667538.1",null,null,"hypothetical protein y0195",{"$nulls":12},73,5.75,116479,"OM",null,0,null,"N",null,"Unknown function","General","Putative exported protein"]
[null,"y0239","(yjcD)",22124159,"NP_667582.1",null,null,"putative symporter for nucleobases/cations",{"$nulls":12},61,5.82,46218,"CM",null,13,null,"N",null,"Unknown function","General","Family includes permeases for diverse substrates such as xanthine, uracil and vitamin C"]
[null,"y0296","ftsN",22124214,"NP_667637.1",null,null,"essential cell division protein",{"$nulls":12},99,10.19,30525,"CM",null,1,null,"N",null,"Cellular processes","Cell division","Has large periplasmic C-terminal domain and localizes to the division site"]
[null,"y0300","(yiaA)",22124218,"NP_667641.1",null,null,"hypothetical protein y0300",{"$nulls":12},74,6.23,17037,"CM",null,4,null,"N",null,"Unknown function","General","Similar to E. coli inner membrane protein YiaA"]
[null,"y0372","wecF",22124287,"NP_667710.1",null,null,"TDP-Fuc4NAc:lipidII transferase",{"$nulls":12},61,9.4,51619,"CM",null,11,null,"N",null,"Cell envelope","Biosynthesis and degradation of murein sacculus and peptidoglycan","Enzyme participating in synthesis of enterobacterial common antigen"]
[null,"y0384","(clcA)",22124299,"NP_667722.1",null,null,"hypothetical protein y0384, putative outer membrane lipoprotein ",{"$nulls":12},403,6.07,6622,"U",null,0,"OM-LP","Y","23-24","Cell envelope","Other","Putative outer membrane lipoprotein in Salmonella typhimurium LT2"]
[null,"y0413","-",22124328,"NP_667751.1",null,null,"putative inner membrane protein y0413",{"$nulls":12},68,9.47,15862,"U",null,1,null,"Y","19-20","Cell envelope","Other","Similar to Salmonella typhimurium LT2 putative inner membrane protein YhhM"]
[null,"y0437","ugpC",22124352,"NP_667775.1",null,null,"ATP-binding component of n-glycerol-3-phosphate  ABC transporter",{"$nulls":12},60,7.11,39461,"C",null,1,null,"N",null,"Transport and binding proteins","Carbohydrates, organic alcohols, and acids","ATP-binding subunit of ABC transporter"]
[null,"y0451","ubiB",22124366,"NP_667789.1",null,null,"putative ubiquinone biosynthesis protein UbiB ",{"$nulls":12},149,6.86,62388,"CM",null,1,null,"N",null,"Biosynthesis of cofactors, prosthetic groups, and carriers","Menaquinone and ubiquinone","2-octaprenylphenol hydroxylase"]
[null,"y0452","tatA",22124367,"NP_667790.1",null,null,"Sec-independent protein translocase protein TatA ",{"$nulls":12},206,6.56,9383,"U",null,1,null,"N",null,"Unknown function","General","Subunit of twin arginine transporter protein translocation apparatus"]
[null,"y0454","tatC",22124369,"NP_667792.1",null,null,"TatABCE protein translocation system subunit ",{"$nulls":12},85,7.74,28706,"CM",null,6,null,"N",null,"Unknown function","General","Subunit of twin arginine transporter protein translocation apparatus"]
[null,"y0480","rplK",22124395,"NP_667818.1",null,null,"50S ribosomal subunit protein L11",{"$nulls":12},190,9.41,14811,"U",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","50S ribosome subunit"]
[null,"y0481","rplA",22124396,"NP_667819.1",null,null,"50S ribosomal subunit protein L1",{"$nulls":12},158,9.56,24787,"U",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","50S ribosome subunit"]
[null,"y0482","rplJ",22124397,"NP_667820.1",null,null,"50S ribosomal subunit protein L10",{"$nulls":12},232,9.33,17722,"U",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","50S ribosome subunit"]
[null,"y0511","gltP",22124426,"NP_667849.1",null,null,"glutamate/aspartate:proton symporter ",{"$nulls":12},90,8.92,47022,"CM",null,12,null,"Y","28-29","Transport and binding proteins","Amino acids, peptides and amines","Dicarboxylate/Amino Acid:Cation Symporter (DAACS) Family, proton/sodium ion:glutamate/aspartate symporter "]
[null,"y0558","terC",22124472,"NP_667895.1",null,null,"putative tellurium resistance protein",{"$nulls":12},242,6.75,35248,"CM",null,8,null,"Y","28-29","Cellular processes","Detoxification","Putative phage inhibition and colicin resistance"]
[null,"y0570","plsB",22124484,"NP_667907.1",null,null,"glycerol-3-phosphate acyltransferase",{"$nulls":12},55,9.33,99096,"U",null,1,null,"N",{"$nulls":3},"Involved in phospholipid biosynthesis "]
[null,"y0630","hfq",22124544,"NP_667967.1",null,null,"putative host factor I for bacteriophage Q beta replication",{"$nulls":12},193,6.9,11124,"U",null,0,null,"N",null,"Regulatory functions","Other","Stimulates the elongation of poly(A) tails"]
[null,"y0800","-",22124713,"NP_668136.1",null,null,"chloride channel protein  ",{"$nulls":12},275,9.34,51040,"CM",null,11,null,"N",null,"Transport and binding proteins","Anions","Acts as an electrical shunt for an outwardly-directed proton pump (CIC chloride carrier channel family)"]
[null,"y0897","rplS",22124807,"NP_668230.1",null,null,"50S ribosomal subunit protein L19",{"$nulls":12},167,10.59,13082,"C",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","50S ribosome subunit"]
[null,"y0946","fadE",22124853,"NP_668276.1",null,null,"putative acyl-CoA dehydrogenase",{"$nulls":12},137,8.42,88912,"CM",null,6,null,"N",null,"Central intermediary metabolism","Other","Functions in fatty acid oxidation"]
[null,"y0953","nqrC",22124860,"NP_668283.1",null,null,"Na-translocating NADH ubiquinone oxidoreductase, gamma chain",{"$nulls":12},63,9.28,31201,"U",null,2,null,"Y","52-53","Energy metabolism","Electron transport","One of the six subunits of one of three families of respiratory NADH dehydrogenases; flavin cofactor"]
[null,"y0956","nqrF",22124863,"NP_668286.1",null,null,"Na-translocating NADH ubiquinone oxidoreductase, beta chain",{"$nulls":12},102,4.95,45426,"C",null,1," ","Y","24-25","Energy metabolism","Electron transport","One of the six subunits of one of three families of respiratory NADH dehydrogenases; flavin cofactor"]
[null,"y0994","secF",22124901,"NP_668324.1",null,null,"protein secretion, membrane protein",{"$nulls":12},352,5.2,37463,"CM",null,6," ","Y","24-25",null,null,"Transporter of multidrug/solvent efflux (RND family), protein export  "]
[null,"y1017","-",22124924,"NP_668347.1",null,null,"major facilitator family transport protein ",{"$nulls":12},87,9.3,48758,"CM",null,12,null,"N",null,"Transport and binding proteins","Other","Putative multidrug efflux pump of MFS superfamily"]
[null,"y1020","cyoB",22124927,"NP_668350.1",null,null,"cytochrome o ubiquinol oxidase subunit I",{"$nulls":12},56,6.6,74067,"CM",null,14,null,"N",null,"Energy metabolism","Electron transport","Integral membrane protein of the CyoABCD cytochrome bo oxidase complex, electron transport chain"]
[null,"y1044","-",22124951,"NP_668374.1",null,null,"glycoprotein/polysaccharide metabolism",{"$nulls":12},125,6.71,17903,"U",null,0,"OM-LP","Y","26-27","Cell envelope","Other","Similar to predicted outer membrane lipoprotein YbaY"]
[null,"y1066","hemH",22124973,"NP_668396.1",null,null,"ferrochelatase",{"$nulls":12},52,7.1,36390,"C",null,1,null,"N",null,"Biosynthesis of cofactors, prosthetic groups, and carriers","Heme, porphyrin, and cobalamin","Involved in protoheme biosynthesis; in some organisms this protein is membrane-associated "]
[null,"y1086","rosB",22124991,"NP_668414.1",null,null,"putative potassium efflux protein",{"$nulls":12},135,5.24,60459,"CM",null,13,null,"Y","25-26","Transport and binding proteins","Cations and iron carrying compounds","Monovalent cation:proton antiporter family (CPA2 family)"]
[null,"y1093","-",22124996,"NP_668419.1",null,null,"putative copper exporting ATPase ",{"$nulls":12},253,5.3,101733,"CM",null,9,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","P-type ATPase superfamily specific for copper transport"]
[null,"y1096","(ybbK)",22125000,"NP_668423.1",null,null,"putative protease",{"$nulls":12},230,5.49,33468,"U",null,1,null,"N",null,"Unknown function","General","Similar to predicted membrane anchored protease YbbK; prohibition homology (PHB) domain family "]
[null,"y1101","(ybbP)",22125005,"NP_668428.1",null,null,"putative oxidoreductase / ABC transporter permease",{"$nulls":12},73,9.55,90078,"CM",null,10,null,"Y","35-36","Transport and binding proteins","Amino acids, peptides and amines","Similar to uncharacterized E. coli ABC transporter permease ybbP"]
[null,"y1120","-",22125024,"NP_668447.1",null,null,"predicted Zn-dependent hydrolases of the beta-lactamase fold",{"$nulls":12},52,8.66,15464,"U",null,2,null,"N",null,"Cell envelope","Other"]
[null,"y1143","-",22125047,"NP_668470.1",null,null,"conserved hypothetical protein",{"$nulls":12},66,5.71,223992,"MSL",null,2,null,"N",null,"Cell envelope","Other","Putative membrane protein"]
[null,"y1190","lnt",22125093,"NP_668516.1",null,null,"apolipoprotein N-acyltransferase",{"$nulls":12},123,9.31,59323,"CM",null,8,null,"Y","40-41","Protein fate","Protein modification and repair","Transfer of the fatty acyl group on membrane lipoproteins"]
[null,"y1264","kdpB",22125164,"NP_668587.1",null,null,"ATPase of high-affinity potassium transport system, B chain",{"$nulls":12},62,6.71,72916,"CM",null,7,null,"N",null,"Unclassified","Role category not yet assigned","Cation-transporting P-type ATPase, one of the components of the high-affinity ATP-driven potassium transport "]
[null,"y1296","lepB",22125196,"NP_668619.1",null,null,"leader peptidase (signal peptidase I)",{"$nulls":12},55,6.9,36811,"CM",null,2,"IM-LP","N",null,"Protein fate","Protein and peptide secretion and trafficking","Cleavage of the amino-terminal leader peptide from secretory proteins"]
[null,"y1325","hcaT",22125224,"NP_668647.1",null,null,"MFS (major facilitator superfamily) transporter",{"$nulls":12},118,9.8,42436,"CM",null,12,null,"N",null,"Energy metabolism","Other","Putative transporter of 3-phenylpropionate across the inner membrane (MFS family)"]
[null,"y1352","-",22125251,"NP_668674.1",null,null,"paral putative membrane protein ",{"$nulls":12},259,6.32,36418,"U",null,1,null,"N",null,"DNA metabolism","DNA replication, recombination, and repair","Inner membrane protein"]
[null,"y1395","-",22125293,"NP_668716.1",null,null,"putative divalent cation (magnesium) transporter",{"$nulls":12},192,5.14,54207,"CM",null,5,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","Magnesium transporter E (Mgt-E) family"]
[null,"y1399","(pstA1)",22125297,"NP_668720.1",null,null,"putative inner membrane permease of high-affinity phosphate ABC transporter ",{"$nulls":12},122,8.99,81288,"CM",null,10,null,"N",null,"Transport and binding proteins","Anions","ABC transporter permease subunit of phosphonate transporter "]
[null,"y1499","nupC",22125396,"NP_668819.1",null,null,"permease of transport system for 3 nucleosides",{"$nulls":12},69,8.73,42509,"CM",null,9,null,"N",null,"Transport and binding proteins","Nucleosides, purines and pyrimidines","Concentrative nucleoside transporter (CNT) family"]
[null,"y1525","yfuB",22125422,"NP_668845.1",null,null,"inner membrane permease of iron ABC transporter",{"$nulls":12},92,9.74,57103,"CM",null,12,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","ABC transporter permease subunit of Yfu transporter of iron "]
[null,"y1630","nuoA",22125525,"NP_668948.1",null,null,"NADH dehydrogenase I chain A",{"$nulls":12},292,9.46,18365,"CM",null,3,null,"Y","43-44","Energy metabolism","Aerobic","Membrane-associated NADH dehydrogenase complex involved in aerobic respiration "]
[null,"y1639","nuoK",22125534,"NP_668957.1",null,null,"NADH dehydrogenase I chain K",{"$nulls":12},103,6.7,10873,"CM",null,3,null,"N",null,"Energy metabolism","Electron transport","Membrane-associated NADH dehydrogenase complex involved in aerobic respiration "]
[null,"y1641","nuoM",22125536,"NP_668959.1",null,null,"NADH dehydrogenase I chain M",{"$nulls":12},60,9.04,56788,"CM",null,15,null,"N",null,"Energy metabolism","Aerobic","Membrane-associated NADH dehydrogenase complex involved in aerobic respiration "]
[null,"y1771","-",22125665,"NP_669088.1",null,null,"putative lipoprotein  y1771",{"$nulls":12},60,9.36,16342,"U",null,1,null,"N",null,"Unknown function","General","Similar to putative E. coli lipoprotein YcfL"]
[null,"y1785","lolC",22125679,"NP_669102.1",null,null,"outer membrane-specific lipoprotein transporter subunit LolC ",{"$nulls":12},51,9.12,43105,"CM",null,4,null,"N",null,"Cell envelope","Other","Permease subunit of the ATP-dependent lipoprotein transport system LolCDE"]
[null,"y1823","motA",22125716,"NP_669139.1",null,null,"flagellar motor protein MotA",{"$nulls":12},89,5.48,32044,"CM",null,4,null,"N",null,"Cellular processes","Chemotaxis and motility","With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane"]
[null,"y1891","yfeE",22125784,"NP_669207.1",null,null,"putative regulator of yfeABCD",{"$nulls":12},117,9.3,20899,"CM",null,3,null,"N",null,"Regulatory functions","Other","Regulator of Yfe operon for iron import"]
[null,"y1894","yfeD",22125787,"NP_669210.1",null,null,"permease for iron and manganese ABC transporter",{"$nulls":12},237,8.62,32181,"CM",null,8,null,"N",null,"Unclassified","Role category not yet assigned","ABC transporter permease subunit of Yfe iron transporter "]
[null,"y1895","yfeC",22125788,"NP_669211.1",null,null,"permease for iron and manganese ABC transporter",{"$nulls":12},115,8.44,31786,"CM",null,8,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds, Amino acids, peptides and amines, Unknown substrate","ABC transporter permease subunit of Yfe transporter of iron "]
[null,"y1905","rplT",22125798,"NP_669221.1",null,null,"50S ribosomal subunit protein L20",{"$nulls":12},56,11.56,13503,"U",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","50S ribosome subunit"]
[null,"y1918","-",22125811,"NP_669234.1",null,null,"undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase",{"$nulls":12},97,6.08,36398,"CM",null,2,null,"N",null,"Cell envelope","Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides","Lipopolysaccharide modification "]
[null,"y1945","-",22125837,"NP_669260.1",null,null,"multidrug efflux protein ",{"$nulls":12},51,9.68,49369,"CM",null,12,null,"Y","29-30","Cellular processes, Transport and binding proteins","Toxin production and resistance, Other","Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase family"]
[null,"y1971","tppB",22125863,"NP_669286.1",null,null,"putative tripeptide transporter permease",{"$nulls":12},58,9.02,56980,"CM",null,14,null,"N",{"$nulls":3},"Proton-dependent dipeptide/tripeptide symporter (POT family)"]
[null,"y1982","pspC",22125874,"NP_669297.1",null,null,"phage shock protein",{"$nulls":12},74,7.93,13455,"U",null,1,null,"N",null,"Cellular processes","Adaptations to atypical conditions","Leucine zipper-containing transcriptional activator of the psp operon in response to infection with bacteriophage"]
[null,"y1985","(ycjF)",22125877,"NP_669300.1",null,null,"conserved inner membrane protein ",{"$nulls":12},69,9.02,39240,"CM",null,4,null,"N",null,"Unclassified","Role category not yet assigned","Similar to conserved inner membrane protein YcjF"]
[null,"y1994","zntB",22125886,"NP_669309.1",null,null,"Zinc transport protein zntB",{"$nulls":12},64,5.07,37791,"U",null,2,null,"N",{"$nulls":3},"CorA metal ion transporter family (MIT family)"]
[null,"y2042","-",22125933,"NP_669356.1",null,null,"hypothetical protein y2042",{"$nulls":12},89,10.53,27736,"CM",null,6,null,"Y","37-38","Unknown function","General","Putative membrane protein"]
[null,"y2071","osmB",22125961,"NP_669384.1",null,null,"osmotically inducible lipoprotein B",{"$nulls":12},77,11.01,6809,"U",null,2,"OM-LP","Y","23-24","No Data","No Data","Inducible by both osmotic stress and growth phase signals "]
[null,"y2232","minC",22126118,"NP_669541.1",null,null,"cell division inhibitor",{"$nulls":12},89,7.7,24759,"U",null,1,null,"N",null,"Cellular processes","Cell division","Ensures correct placement of septum during cell division by suppressing formation of septa at aberrant loci "]
[null,"y2247","msbB",22126133,"NP_669556.1",null,null,"lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase",{"$nulls":12},91,8.61,37064,"CM",null,1,null,"N",null,"Cellular processes","Adaptations to atypical conditions","Involved in phospholipid biosynthesis "]
[null,"y2352","chaA",22126236,"NP_669659.1",null,null,"sodium-calcium/proton antiporter",{"$nulls":12},60,6.92,39127,"CM",null,11,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","Calcium:cation antiporter 2 (CaCA) family "]
[null,"y2356","hmsS",22126240,"NP_669663.1",null,null,"inner membrane hemin storage locus protein HmsS",{"$nulls":12},104,6.18,17491,"C",null,2,null,"N",null,"Unclassified","Role category not yet assigned","Required for hemin storage phenotype, part of Hms hemin storage system locus"]
[null,"y2357","(pgaC)",22126241,"NP_669664.1",null,null,"glycosyltransferase, probably involved in cell wall biogenesis",{"$nulls":12},124,9.68,51996,"CM",null,5,null,"N",{"$nulls":3},"Required for hemin storage phenotype, part of Hms hemin storage system locus"]
[null,"y2367","-",22126251,"NP_669674.1",null,null,"putative integral membrane protein",{"$nulls":12},101,8.5,53936,"CM",null,8,null,"N",null,"Cell envelope","Other","Shows certain similarities to eukaryotic H(+)-transporting ATPases "]
[null,"y2370","-",22126254,"NP_669677.1",null,null,"putative integral membrane protein",{"$nulls":12},243,5.24,71311,"CM",null,8," ","Y","23-24","Cell envelope","Other","Iron permease FTR1 family protein"]
[null,"y2371","-",22126255,"NP_669678.1",null,null,"putative transport protein of MFS family",{"$nulls":12},243,9.83,57777,"CM",null,14,null,"N",null,"Cell envelope","Other","Major facilitator superfamily (MFS) transport protein for multidrug eflux"]
[null,"y2374","ansP",22126258,"NP_669681.1",null,null,"L-asparagine permease",{"$nulls":12},82,9.1,55288,"CM",null,12,null,"N",null,"Transport and binding proteins","Amino acids, peptides and amines","Amino acid / polyamine cation (APC) family of transporters"]
[null,"y2447","cycA",22126330,"NP_669753.1",null,null,"symporter of D-alanine, D-serine, and glycine",{"$nulls":12},123,9.48,52278,"CM",null,12,null,"N",null,"Transport and binding proteins","Amino acids, peptides and amines","Amino acid / polyamine cation (APC) family of transporters"]
[null,"y2449","wrbA",22126332,"NP_669755.1",null,null,"trp repressor binding protein",{"$nulls":12},118,7.07,21477,"CM",null,3,null,"N",null,"Amino acid biosynthesis","Aromatic amino acid family","NAD(P)H:quinone oxidoreductase activity, provides reduced, response to oxidative stress"]
[null,"y2453","putP",22126336,"NP_669759.1",null,null,"major sodium/proline symporter",{"$nulls":12},57,8.94,53533,"CM",null,13,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","Solute:sodium symporter (SSS) family"]
[null,"y2458","-",22126341,"NP_669764.1",null,null,"putative ATP-binding component of glutamate/aspartate ABC transporter ",{"$nulls":12},81,8.91,27972,"CM",null,0,null,"N",null,"Transport and binding proteins","Amino acids, peptides and amines","ABC transporter ATP-binding subunit of putative glutamine/glutamate/asparatate transporter "]
[null,"y2540","hpaX",22126422,"NP_669845.1",null,null,"hypothetical 4-hydroxyphenylacetate permease",{"$nulls":12},58,9.65,49973,"CM",null,12,null,"N",null,"Transport and binding proteins","Unknown substrate","Major facilitator (MFS) superfamily transporter specific for hydroxyphenylacetate"]
[null,"y2612","(yeeF)",22126493,"NP_669916.1",null,null,"amino acid permease   ",{"$nulls":12},70,8.93,50150,"CM",null,12,null,"N",null,"Transport and binding proteins","Other","Amino acid/polyamine organocation transporter (APC) family"]
[null,"y2615","-",22126495,"NP_669918.1",null,null,"ribose ABC transporter permease ",{"$nulls":12},85,9.46,34904,"CM",null,10,null,"N",null,"Transport and binding proteins","Carbohydrates, organic alcohols, and acids","Permease subunit of putative ribose ABC transporter "]
[null,"y2640","ysuI",22126519,"NP_669942.1",null,null,"putative siderophore biosynthetic protein",{"$nulls":12},69,6.11,50784,"U",null,1,null,"N",null,"Cell envelope, Cellular processes, Protein fate, Regulatory functions, DNA metabolism, Protein synthesis, Unknown function","Cell division, Protein folding and stabilization, DNA replication, recombination, and repair, Degradation of proteins, peptides, and glycopeptides, Ribosomal proteins: synthesis and modification, General , Other","Synthesis and transport of small molecules / cations"]
[null,"y2654","-",22126533,"NP_669956.1",null,null,"hypothetical protein y2654",{"$nulls":12},112,9.2,16779,"CM",null,4,null,"N",null,"Unknown function","General","Similar to conserved inner membrane protein YohJ of E  coli"]
[null,"y2777","msbA",22126655,"NP_670078.1",null,null,"ATP-binding transport protein; multicopy suppressor of htrB",{"$nulls":12},59,7.16,64592,"CM",null,5,null,"Y","38-39","Transport and binding proteins","Other","Essential for the translocation of lipopolysaccharides from the inner to the outer leaflet of the inner membrane "]
[null,"y2789","focA",22126667,"NP_670090.1",null,null,"probable formate transporter",{"$nulls":12},50,7.04,30999,"CM",null,6,null,"N",null,"Energy metabolism","Other","Formate/nitrite transporter (FNT) family"]
[null,"y2800","ftsK",22126676,"NP_670099.1",null,null,"cell division protein",{"$nulls":12},61,4.79,140879,"OM",null,4,null,"N",null,"Cellular processes","Cell division","Essential cell division protein which colocalizes with FtsZ to the septal ring structure"]
[null,"y2801","lrp",22126678,"NP_670101.1",null,null,"leucine-responsive transcriptional regulator ",{"$nulls":12},174,8.56,18939,"C",null,1,null,"N",null,"Central intermediary metabolism","Other","Acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system"]
[null,"y2857","-",22126734,"NP_670157.1",null,null,"putative transport protein",{"$nulls":12},60,8.75,60191,"CM",null,11,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","Nucleobase:cation symporter 2 (NCS-2) family, putative specificity for uracil and xanthine"]
[null,"y2862","sdaC",22126739,"NP_670162.1",null,null,"probable serine transporter",{"$nulls":12},198,9.23,48363,"CM",null,10,null,"N",null,"Transport and binding proteins","Amino acids, peptides and amines","Hydroxy / aromatic acid transporter family (HAAAP family)"]
[null,"y2885","fruA",22126762,"NP_670185.1",null,null,"PTS system, fructose-specific IIBC transport protein",{"$nulls":12},134,8.81,57748,"CM",null,10,null,"N",null,"Energy metabolism","Other","Fructose-specific transport protein of PEP:PTS system"]
[null,"y2907","(yeiU)",22126784,"NP_670207.1",null,null,"putative inner membrane protein y2907",{"$nulls":12},57,9.69,26147,"CM",null,5,null,"N",null,"Unknown function","General","PAP2-like protein, a super-family of histidine phosphatases and vanadium haloperoxidases"]
[null,"y2911","(yejB)",22126788,"NP_670211.1",null,null,"putative transport system permease protein",{"$nulls":12},261,8.61,40611,"CM",null,6,null,"N",null,"Transport and binding proteins","Amino acids, peptides and amines","ABC transporter permease subunit for oligopeptide transport "]
[null,"y2912","-",22126789,"NP_670212.1",null,null,"putative transport system permease protein",{"$nulls":12},247,9.54,38133,"CM",null,6,null,"Y","39-40","Transport and binding proteins","Amino acids, peptides and amines","ABC transporter permease subunit for oligopeptide transport "]
[null,"y2924","-",22126801,"NP_670224.1",null,null,"putative sulfatase",{"$nulls":12},63,6.13,67432,"CM",null,5,null,"N",null,"Cell envelope","Other","Similar to E. coli inner membrane protein yejM"]
[null,"y2939","-",22126816,"NP_670239.1",null,null,"hypothetical protein y2939",{"$nulls":12},53,6.04,21200,"U",null,0,null,"N",null,"Mobile and extrachromosomal element functions","Prophage functions","Putative bacteriophage Mu Gp45 protein"]
[null,"y2946","-",22126823,"NP_670246.1",null,null,"putative bacteriophage tail sheath protein ",{"$nulls":12},58,5.53,53458,"U",null,0,null,"N",null,"Mobile and extrachromosomal element functions","Prophage functions","Similar to Mu-like prophage tail sheath protein gpL "]
[null,"y2957","ompT",22126834,"NP_670257.1",null,null,"outer membrane protein 3b (a), protease VII",{"$nulls":12},105,5.97,34863,"OM",5,0," ","Y","25-26","Protein fate","Degradation of proteins, peptides, and glycopeptides, Other","membrane protease; involved in virulence in many organisms"]
[null,"y3004","-",22126881,"NP_670304.1",null,null,"putative inner membrane permease of phosphonate ABC transporter",{"$nulls":12},196,9.99,33421,"CM",null,5,null,"N",null,"Transport and binding proteins","Anions","ABC transporter permease subunit of phosphonate transporter "]
[null,"y3005","-",22126882,"NP_670305.1",null,null,"putative inner membrane permease of phosphonate ABC transporter",{"$nulls":12},147,9.52,32108,"CM",null,4,null,"N",null,"Transport and binding proteins","Other","ABC transporter permease subunit of phosphonate transporter "]
[null,"y3007","phnC",22126884,"NP_670307.1",null,null,"ATP-binding component of phosphonate transport",{"$nulls":12},95,8.82,32469,"CM",null,0,null,"N",null,"Transport and binding proteins","Amino acids, peptides and amines, Unknown substrate","ABC transporter ATP-binding subunit of phosphonate transporter "]
[null,"y3057","tolR",22126933,"NP_670356.1",null,null,"colicin uptake protein TolR ",{"$nulls":12},109,5.66,15500,"CM",null,1," ","N",null,"Transport and binding proteins","Other","membrane spanning protein in TolA-TolQ-TolR complex, colicin uptake"]
[null,"y3063","cydA",22126939,"NP_670362.1",null,null,"cytochrome d terminal oxidase, polypeptide subunit I",{"$nulls":12},270,6.04,58231,"CM",null,9,null,"N",null,"Energy metabolism","Electron transport","Integral membrane protein of the CydAB cytochrome bd oxidase complex, electron transport chain"]
[null,"y3128","(yaeL)",22127004,"NP_670427.1",null,null,"Zinc metallopeptidase",{"$nulls":12},392,6.93,49398,"CM",null,4,null,"N",null,"Protein fate","Degradation of proteins, peptides, and glycopeptides","Putative membrane-associated Zn-dependent protease in Salmonella typhimurium LT2"]
[null,"y3172","lgt",22127048,"NP_670471.1",null,null,"phosphatidylglycerol-prolipoprotein diacylglyceryl transferase",{"$nulls":12},118,9.48,32787,"CM",null,7,null,"N",null,"Protein fate","Protein modification and repair","Transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein"]
[null,"y3278","creD",22127154,"NP_670577.1",null,null,"inner membrane protein",{"$nulls":12},118,6.51,56065,"CM",null,6,null,"N",null,"Cellular processes","Toxin production and resistance","Tolerance to colicin E2 "]
[null,"y3329","-",22127205,"NP_670628.1",null,null,"putative resistance protein",{"$nulls":12},73,9.34,20795,"CM",null,4,null,"N",null,"Cell envelope","Other","Putative involvement in transport; drug/analog sensitivity, Similar to E. coli inner membrane protein YggT"]
[null,"y3344","-",22127220,"NP_670643.1",null,null,"putative permease of ribose ABC transporter",{"$nulls":12},51,9.49,35855,"CM",null,10,null,"N",null,"Transport and binding proteins","Carbohydrates, organic alcohols, and acids","ABC transporter / permease component"]
[null,"y3396","yapH",22127272,"NP_670695.1",null,null,"putative autotransporter adhesin",{"$nulls":12},59,4.11,370936,"MSL",4,0,null,"N",null,"Cell envelope","Other","Cell exterior constituents and surface structure; virulence factor"]
[null,"y3506","plsC",22127380,"NP_670803.1",null,null,"1-acyl-sn-glycerol-3-phosphate acyltransferase",{"$nulls":12},71,9.66,27188,"U",null,2,null,"N",null,"Fatty acid and phospholipid metabolism","Biosynthesis","Catalyzes the second step in phospholipid biosynthesis"]
[null,"y3532","(plsY)",22127406,"NP_670829.1",null,null,"putative glycerol-3-phosphate acyltransferase PlsY",{"$nulls":12},266,9.39,26764,"CM",null,5,null,"N",null,"Cell envelope","Other","Involved in phospholipid biosynthesis"]
[null,"y3554","-",22127428,"NP_670851.1",null,null,"putative sodium ion:proton antiporter",{"$nulls":12},107,8.48,51214,"CM",null,12,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","Similar to Na+/H+ antiporters, sodium ion:proton antiporter (NhaC) family "]
[null,"y3588","hdeD",22127462,"NP_670885.1",null,null,"acid-resistance membrane protein ",{"$nulls":12},58,9.51,20492,"CM",null,6,null,"Y","46-47","Unclassified","Role category not yet assigned","Inner membrane protein"]
[null,"y3595","-",22127469,"NP_670892.1",null,null,"Na/dicarboxylate symporter",{"$nulls":12},59,6.95,45546,"CM",null,9,null,"N",null,"Transport and binding proteins","Carbohydrates, organic alcohols, and acids","Sodium ion:serine/threonine symporter of Dicarboxylate/amino acid:cation symporter (DAACS) family "]
[null,"y3626","murG",22127500,"NP_670923.1",null,null,"UDP-N-acetylglucosamine:N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase",{"$nulls":12},160,9.72,37750,"CM",null,2,null,"Y","26-27","Cell envelope","Biosynthesis and degradation of murein sacculus and peptidoglycan","Involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis"]
[null,"y3702","rpsT",22127576,"NP_670999.1",null,null,"30S ribosomal subunit protein S20",{"$nulls":12},50,11.14,9840,"U",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","30S ribosome subunit"]
[null,"y3707","(yaaH)",22127581,"NP_671004.1",null,null,"putative inner membrane protein y3707",{"$nulls":12},358,4.92,21647,"CM",null,5,null,"N",null,"Cell envelope","Other","Putative inner membrane protein yaaH in E. coli K12"]
[null,"y3709","-",22127583,"NP_671006.1",null,null,"putative proline/betaine transporter",{"$nulls":12},54,9.4,50471,"CM",null,12,null,"N",null,"Transport and binding proteins","Other","Major facilitator (MFS) superfamily transporter  "]
[null,"y3728","-",22127602,"NP_671025.1",null,null,"putative cation transport protein",{"$nulls":12},66,5.69,99150,"CM",null,10,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","Cation-transporting P-type ATPase (possibly specific for calcium)"]
[null,"y3759","mexB",22127630,"NP_671053.1",null,null,"putative multidrug resistance protein",{"$nulls":12},555,5.17,113317,"CM",null,12,null,"N",null,"Transport and binding proteins","Cations and iron carrying compounds","Transporter of multidrug/solvent efflux (RND family, HAE1 subfamily)  "]
[null,"y3762","-",22127633,"NP_671056.1",null,null,"hypothetical protein y3762",{"$nulls":12},150,9.34,44879,"CM",null,11,null,"Y","33-34","Cell envelope","Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides","putative O-antigen biosynthesis protein RfaL (Y. pestis Microtus)"]
[null,"y3801","rbn",22127672,"NP_671095.1",null,null,"tRNA processing exoribonuclease BN",{"$nulls":12},65,9.24,35434,"CM",null,7,null,"N",null,"Transcription","RNA processing","Binuclear zinc phosphodiesterase, cleaves the 3'-terminal portion of tRNAs and various short unstructured RNAs "]
[null,"y3823","-",22127694,"NP_671117.1",null,null,"hypothetical protein y3823",{"$nulls":12},109,6.61,48925,"OM",null,1," ","Y","31-32","Cellular processes","Toxin production and resistance, Pathogenesis","putative member of ShlA/HecA/FhaA exoprotein family"]
[null,"y3898","glpG",22127769,"NP_671192.1",null,null,"intramembrane serine protease GlpG ",{"$nulls":12},68,6.64,31285,"CM",null,6,null,"N",null,"Energy metabolism","Anaerobic","Responsible for the cleavage between Ser and Asp residues of proteins in regions of high local  hydrophilicity"]
[null,"y3911","feoB",22127781,"NP_671204.1",null,null,"ferrous iron transport protein B",{"$nulls":12},84,5.94,84745,"CM",null,11,null,"N",{"$nulls":3},"Ferrous iron uptake transporter family"]
[null,"y3989","rpsJ",22127859,"NP_671282.1",null,null,"30S ribosomal subunit protein S10",{"$nulls":12},194,9.85,11759,"U",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","30S ribosome subunit"]
[null,"y3993","rplB",22127863,"NP_671286.1",null,null,"50S ribosomal subunit protein L2",{"$nulls":12},536,10.95,30168,"U",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","50S ribosome subunit"]
[null,"y3994","rplV",22127864,"NP_671287.1",null,null,"50S ribosomal subunit protein L22",{"$nulls":12},134,10.23,12179,"U",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","50S ribosome subunit"]
[null,"y3995","rpsC",22127865,"NP_671288.1",null," ","30S ribosomal subunit protein S3",{"$nulls":12},989,10.25,25813,"C",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","30S ribosome subunit"]
[null,"y3996","rplP",22127866,"NP_671289.1",null,null,"50S ribosomal subunit protein L16",{"$nulls":12},165,10.86,15378,"U",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","50S ribosome subunit"]
[null,"y3999","rplN",22127869,"NP_671292.1",null,null,"50S ribosomal subunit protein L14",{"$nulls":12},166,10.43,13688,"U",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","50S ribosome subunit"]
[null,"y4003","rpsH",22127873,"NP_671296.1",null,null,"30S ribosomal subunit protein S8, and regulator",{"$nulls":12},107,9.55,14157,"U",null,1,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","30S ribosome subunit"]
[null,"y4004","rplF",22127874,"NP_671297.1",null,null,"50S ribosomal subunit protein L6",{"$nulls":12},209,9.65,18972,"U",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","50S ribosome subunit"]
[null,"y4006","rplR",22127876,"NP_671299.1",null,null,"50S ribosomal subunit protein L18",{"$nulls":12},80,10.62,12803,"C",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","50S ribosome subunit"]
[null,"y4007","rpsE",22127877,"NP_671300.1",null,null,"30S ribosomal subunit protein S5",{"$nulls":12},691,10.16,17522,"U",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","30S ribosome subunit"]
[null,"y4009","rplO",22127879,"NP_671302.1",null,null,"50S ribosomal subunit protein L15",{"$nulls":12},104,11.13,15197,"C",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","50S ribosome subunit"]
[null,"y4010","prlA",22127880,"NP_671303.1",null,null,"preprotein translocase subunit SecY",{"$nulls":12},137,9.89,48599,"CM",null,10,null,"N",null,"Protein fate","Protein and peptide secretion and trafficking","Forms heterotrimeric complex in the membrane with SecE and SecG"]
[null,"y4016","rplQ",22127886,"NP_671309.1",null,null,"50S ribosomal subunit protein L17",{"$nulls":12},151,11.21,14580,"U",null,0,null,"N",null,"Protein synthesis","Ribosomal proteins: synthesis and modification","50S ribosome subunit"]
[null,"y4035","(pldB3)",22127905,"NP_671328.1",null,null,"putative membrane protein",{"$nulls":12},198,8.94,54025,"CM",null,1,null,"N",null,"Cell envelope","Other","Contains esterase/lipase/thioesterase, active site"]
[null,"y4093","(yiaD)",22127962,"NP_671385.1",null,null,"putative outer membrane protein",{"$nulls":12},231,9.71,22219,"OM",null,3,"OM-LP","Y","20-21","Cell envelope","Other","OmpA /OmpF porin family"]
[null,"y4103","-",22127972,"NP_671395.1",null,null,"hypothetical protein y4103",{"$nulls":12},111,4.72,12317,"U",null,1,"OM-LP","Y","30-31","Unknown function","General","Putative lipoprotein"]
[null,"y4129","pstA",22127997,"NP_671420.1",null,null,"inner membrane permease of high-affinity phosphate ABC transporter ",{"$nulls":12},109,10.14,32311,"CM",null,6,null,"N",null,"Transport and binding proteins","Anions","ABC transporter permease subunit of phosphate transporter "]
[null,"y4130","pstC",22127998,"NP_671421.1",null,null,"phosphate transporter permease subunit ",{"$nulls":12},68,6.62,34886,"CM",null,6,null,"N",null,"Transport and binding proteins","Anions","ABC transporter permease subunit of high affinity phosphate transporter "]
[null,"y4140","atpE",22128008,"NP_671431.1",null,null,"membrane-bound ATP synthase, F0 sector, subunit c",{"$nulls":12},63,4.44,8250,"CM",null,2,null,"Y","23-24","Energy metabolism","ATP-proton motive force interconversion","Part of the membrane proton channel F0"]
[null,"YKCD1p18","lcrF",31795271,"NP_857733",null,null,"transcriptional regulator VirF",{"$nulls":12},53,9.06,30813,"U",null,0,null,"N",{"$nulls":3},"Bacterial regulatory helix-turn-helix proteins of AraC family"]
[]
["a) protein spot numbers listed match those displayed in Figure 1 and Figures 1-8, Supplemental Information;"]
["b) locus tags from Yersinia pestis KIM genome annotations including pMT1 and pPCP1 plasmids; "]
["c) gene names are derived from KIM genome annotations (databases in NCBI and ERIC: www.ericbrc.org/portal/eric); if not annotated, gene names listed in parentheses are from genome annotations ofE. coli K12 or Y. pestis Microtus 91001,  if sequence identity score >70%; "]
[]
["d) protein accession numbers in NCBI: gi| numbers and NP_ Ref. Seq. numbers from KIM genome;  "]
["e) proteins detected in high Mr size exclusion chromatography fractions (>250 kDa) derived from hpH-MBR samples (Y=Yes); abbr. 'MPC': multi-subunit protein complex"]
["f) subcellular localization and membrane attachement of proteins based on differential 2D gel display data: i-M: integral membrane proteins and less water-soluble peripheral membrane proteins; i-OM: integral and lipid-anchored outer membrane proteins; p-M: more water-soluble peripheral membrane proteins; p-M*: tentative peripheral membrane proteins with high abundance in soluble fractions; C/R: cytoplasmic/ribosomal membrane-contaminating proteins;  "]
[]
[]
["g) information derived from Y. pestis KIM genome annotations or, in a few cases, orthologs in E. coli K12 or Y. pestis Microtus 91001; "]
["h-k) geometric means of spot volumes (XN) for proteins in differential 2D gel display analysis; the four subcellular fractions are CYP: cytoplasmic, hs-MBR: high-salt extracted membrane, hpH-MBR: alkaline extracted membrane, and usb-MBR: urea/thiourea/amidosulfobetaine-14-extracted membrane fractions; in parentheses: coefficients of variation (CV); N.A. spot not reproducibly observed in a particular fraction; blank space: spot not reproducibly observed in the cell examined growth condition or the examined pH range of the gels;  "]
[]
[]
[]
["l) Enrichment factor for a protein in all membrane vs. CYP fractions (EM); equation is listed in the 'Method' section; blank space: missing value if XN values (see h-k notes) not determined in membrane and/or CYP fractions; "]
[]
["m) Enrichment factor for a protein in hpH-MBR and usb-MBR vs. hs-MBR fractions (EIM); see other notes above under l); "]
["n-q) spot quantities (VS) for proteins in differential 2DGE display were chosen from one of several examined growth conditions and pH ranges in gels; CVs were not determined, and the highest observed quantitiy of a given protein spot was listed; +, protein was identified by MS, but not resolved as a distinct spot to allow VS measurements; * in CYP column: spot quantity for periplasmic protein from PPS fraction;  "]
[]
[]
["r) Mascot score: left column, highest MS score obtained from 2DGE spot in MALDI-TOFTOF or nESI-LC-MS/MS experiments; right column, amino acid sequence range for a protein identified by MS analysis from a single 2DGE spot; MALDI-TOFTOF (M); nESI-LC-MS/MS ion trap (L); the most N-terminal tryptic peptides that were identified are highlighted in RED and were an indicator of protein association with the inner membrane; the Mascot score threshold for tryptic peptides from LC-MS/MS experiments was set at 15; several experimental MS datasets per protein are listed; "]
[]
[]
[]
["s) MS score obtained from 2D-LC-MS/MS analysis (see 'Methods section'); "]
["t) pI and Mr values of proteins were calculated from polypeptide sequences annotated in the KIM genome; "]
["u-y) bioinformatic data for subcellular localizations (PSORTb), abbreviations: cytoplasm, P: periplasm, MSL: multiple cellular localizations, U:unknown; this is followed by conserved membrane association sequence motifs (BOMP, TMHMM, LipoP) and protein export motifs (SignalP); details are provided in the 'Methods' section; briefly, BOMP recognizes β-barrel outer membrane proteins, TMHMM inner membrane  α-helical transmembrane domains, LipoP lipid anchor motifs, and SignalP sequences processed in the general secretion pathway; abbreviations for LipoP column: IM-LP, inner membrane-anchored lipoprotein; OM-LP: outer membrane-anchored lipoprotein; (LP) only annotation data suggest lipoprotein motif; y) predicted signal peptidase I or II cleavage sites (selected using Hidden Markow Model algorithm);"]
[]
[]
[]
[]
[]
["z) primary and secondary protein functional role categories according to CMR data (http://.cmr.jcvi.org);"]
["aa) proteins with potential functions according to data in the KIM genome annotations, the E. coli or Y. pestis literature or databases assessing conserved structural motifs such as TIGRFam, PFam, TransportDB and EcoCyc (http://www.ecocyc.org); "]
[]
["ab) Mascot scores from 2D-LC-MS/MS experiments for proteins identified in 2DGE and 2D-LC-MS/MS experiments are listed in Part 1 (note s);"]