{"text_format":"3","workbook":"xls","n_sheets":3,"sheets":["Reporter-TFs","Reporter-GOs","Reporter-Metabolites"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Reporter-TFs","index":0,"n_rows":555,"n_cols":4,"rows_kept":555,"merged":[[1,0,1,3]],"flags":["formulas_cached_only"]}
["Transcription Factor/Regulator","Number of neighbors","P-value","SGD definition"]
["Complete list of reporter TFs"]
[]
["HAP5",22,0.00156301,"Subunit of the heme-activated, glucose-repressed Hap2/3/4/5 CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; required for assembly and DNA binding activity of the complex"]
["HAP4",26,0.00227342,"Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex"]
["SLY1",12,0.00332625,"Hydrophilic protein involved in vesicle trafficking between the ER and Golgi; SM (Sec1/Munc-18) family protein that binds the tSNARE Sed5p and stimulates its assembly into a trans-SNARE membrane-protein complex"]
["HAP3",25,0.00422258,"Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences contributing to both complex assembly and DNA binding"]
["SLN1",2,0.00570855,"Histidine kinase osmosensor that regulates a MAP kinase cascade; transmembrane protein with an intracellular kinase domain that signals to Ypd1p and Ssk1p, thereby forming a phosphorelay system similar to bacterial two-component regulators"]
["TRS130",1,0.0109075,"One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in ER to Golgi membrane traffic; mutation activates transcription of OCH1"]
["HAP2",28,0.0138842,"Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences sufficient for both complex assembly and DNA binding"]
["FAR1",2,0.0147143,"Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone; also forms a complex with Cdc24p, Ste4p, and Ste18p that may specify the direction of polarized growth during mating; potential Cdc28p substrate"]
["HYM1",2,0.0193607,"Component of the RAM signaling network that is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with Kic1p and Sog2p, localizes to sites of polarized growth during budding and during the mating response"]
["THI2",8,0.0229733,"Zinc finger protein of the Zn(II)2Cys6 type, probable transcriptional activator of thiamine biosynthetic genes"]
["RAP1",26,0.0244595,"DNA-binding protein involved in either activation or repression of transcription, depending on binding site context; also binds telomere sequences and plays a role in telomeric position effect (silencing) and telomere structure"]
["SWI6",31,0.0292031,"Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; localization regulated by phosphorylation; potential Cdc28p substrate"]
["YHP1",1,0.0305562,"One of two homeobox transcriptional repressors (see also Yox1p), that bind to Mcm1p and to early cell cycle box (ECB) elements of cell cycle regulated genes, thereby restricting ECB-mediated transcription to the M/G1 interval"]
["YOX1",1,0.0305562,"Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; potential Cdc28p substrate"]
["GCR1",18,0.0344583,"Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p"]
["THI3",9,0.0359599,"Probable decarboxylase, required for expression of enzymes involved in thiamine biosynthesis; may have a role in catabolism of amino acids to long-chain and complex alcohols"]
["CMD1",1,0.038662,"Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca++ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin"]
["GCD1",4,0.0526356,"Gamma subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression"]
["MSN5",3,0.0568373,"Karyopherin involved in nuclear import and export; shown to be responsible for nuclear import of replication protein A and for export of several proteins including Swi6p, Far1p, and Pho4p; cargo dissociation involves binding to RanGTP"]
["SEC7",1,0.057285,"Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles"]
["CDC39",4,0.0725667,"Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor"]
["SSA3",1,0.0839827,"ATPase involved in protein folding and the response to stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm"]
["CUP2",3,0.0858998,"Copper-binding transcription factor; activates transcription of the metallothionein genes CUP1-1 and CUP1-2 in response to elevated copper concentrations"]
["VDE1",1,0.0875253,{"$error":"#N/A"}]
["KAR4",2,0.0909326,"Transcription factor required for induction of KAR3 and CIK1 during mating, also required during meiosis; exists in two forms, a slower-migrating form more abundant during vegetative growth and a faster-migrating form induced by pheromone"]
["MBP1",23,0.0911786,"Transcription factor involved in regulation of cell cycle progression from G1 to S phase, forms a complex with Swi6p that binds to MluI cell cycle box regulatory element in promoters of DNA synthesis genes"]
["MET1",3,0.0985389,"S-adenosyl-L-methionine uroporphyrinogen III transmethylase, involved in sulfate assimilation, methionine metabolism, and siroheme biosynthesis"]
["ZAP1",17,0.107986,"Zinc-regulated transcription factor, binds to zinc-responsive promoter elements to induce transcription of certain genes in the presence of zinc; regulates its own transcription; contains seven zinc-finger domains"]
["SRP101",4,0.111179,"Signal recognition particle (SRP) receptor - alpha subunit; contain GTPase domains; involved in SRP-dependent protein targeting; interacts with SRP102p"]
["RPN4",7,0.115888,"Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally regulated by various stress responses"]
["BUD14",1,0.119054,"Protein involved in bud-site selection, Bud14p-Glc7p complex functions as a cortical regulator of dynein; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern"]
["CDC36",1,0.119054,"Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor"]
["RGA1",1,0.119054,"GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth"]
["STE4",1,0.119054,"G protein beta subunit, forms a dimer with Ste18p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste18p to dampen signaling; may recruit Rho1p to the polarized growth site during mating; contains WD40 repeats"]
["UBP3",1,0.119054,"Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde and retrograde transport between endoplasmic reticulum and Golgi compartments; inhibitor of gene silencing; cleaves ubiquitin fusions but not polyubiquitin"]
["SUT2",2,0.121244,"Putative transcription factor; multicopy suppressor of mutations that cause low activity of the cAMP/protein kinase A pathway; highly similar to Sut1p"]
["BCK2",2,0.124726,"Protein rich in serine and threonine residues involved in protein kinase C signaling pathway, which controls cell integrity; overproduction suppresses pkc1 mutations"]
["SPO1",3,0.127807,"Meiosis-specific protein with similarity to phospholipase B, required for meiotic spindle pole body duplication and separation; required for spore formation"]
["SDS3",3,0.131718,"Component of the Rpd3p/Sin3p deacetylase complex required for its structural integrity and catalytic activity, involved in transcriptional silencing and required for sporulation; cells defective in SDS3 display pleiotropic phenotypes"]
["CTK1",1,0.132049,"Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing"]
["RIM8",1,0.136578,"Protein of unknown function, involved in the proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans PalF"]
["YVH1",1,0.136578,"Protein phosphatase involved in vegetative growth at low temperatures, sporulation, and glycogen accumulation; transcription induced by low temperature and nitrogen starvation; member of the dual-specificity family of protein phosphatases"]
["MOT3",18,0.137591,"Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes "]
["SNF7",7,0.137745,"One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes"]
["SLK19",1,0.147821,"Kinetochore-associated protein required for normal segregation of chromosomes in meiosis and mitosis; component of the FEAR regulatory network, which promotes Cdc14p release from the nucleolus during anaphase; potential Cdc28p substrate"]
["TPO1",1,0.147821,"Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane"]
["YER064C",1,0.147821,{"$error":"#N/A"}]
["CAF16",4,0.15336,"Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation; putative ABC ATPase; interacts with Ssn2p, Ssn3p, and Ssn8p"]
["FET3",2,0.166061,"Ferro-O2-oxidoreductase required for high-affinity iron uptake and involved in mediating resistance to copper ion toxicity, belongs to class of integral membrane multicopper oxidases"]
["CLN2",5,0.166096,"G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)"]
["PTR3",5,0.167307,"Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes"]
["CLN1",2,0.17006,"G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)"]
["REB1",9,0.185629,"RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription"]
["SWI4",23,0.197189,"DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activator that in concert with MBF (Mbp1-Swi6p) regulates late G1-specific transcription of targets including cyclins and genes required for DNA synthesis and repair"]
["NPR1",2,0.198203,"Protein kinase that stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation"]
["NOT3",3,0.198997,"Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation"]
["PTI1",3,0.201236,"Pta1p Interacting protein"]
["MGA2",2,0.202589,"ER membrane protein involved, with its homolog Spt23p, in regulation of OLE1 transcription; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting"]
["HAP1",24,0.205216,"Zinc finger transcription factor involved in the complex regulation of gene expression in response to levels of heme and oxygen; the S288C sequence differs from other strain backgrounds due to a Ty1 insertion in the carboxy terminus"]
["DUN1",8,0.212325,"Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair"]
["GIS1",2,0.212407,"Transcriptional factor, involved in the expression of genes during nutrient limitation; also involved in the negative regulation of DPP1 and PHR1"]
["GAT1",9,0.214292,"Transcriptional activator of genes involved in nitrogen catabolite repression, member of the GATA family of DNA binding proteins; activity and localization regulated by nitrogen limitation and Ure2p"]
["NDD1",3,0.21469,"Transcriptional activator essential for nuclear division; localized to the nucleus; essential component of the mechanism that activates the expression of a set of late-S-phase-specific genes"]
["CKS1",1,0.215339,"Subunit of the Cdc28 protein kinase, required for mitotic proteolysis, may also be involved in the proteolysis of the G1 cyclins"]
["MAC1",8,0.21607,"Copper-sensing transcription factor involved in regulation of genes required for high affinity copper transport"]
["KCS1",2,0.216631,"Inositol hexaphosphate kinase, phosphorylates inositol hexakisphosphate (InsP6) to diphosphoinositol polyphosphates, required for proper vacuole morphology and involved in salt stress response, contains two leucine heptad repeats"]
["STE20",3,0.21737,"Signal transducing kinase of the PAK (p21-activated kinase) family, involved in pheromone response and pseudohyphal/invasive growth pathways, activated by Cdc42p; binds Ste4p at a GBB motif present in noncatalytic domains of PAK kinases"]
["GDI1",1,0.218132,"GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4/Ypt/rab family of GTP binding proteins"]
["STE5",2,0.230968,"Scaffold protein that, in response to pheromone, shuttles from the nucleus to the plasma membrane and assembles kinases Ste11p, Ste7p, and Fus3p into a specific signaling complex; active oligomeric form interacts with Ste4p-Ste18p complex"]
["TOM70",1,0.230991,"Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins"]
["CAF4",5,0.233738,"WD40 repeat-containing protein associated with the CCR4-NOT complex, interacts in a Ccr4p-dependent manner with Ssn2p"]
["MOT2",4,0.236895,"Component of the CCR4-NOT transcription regulatory complex, which represses transcription, at least in part, by inhibiting functional TBP-DNA interactions and also aids in transcription elongation; interacts with C-terminal region of Not1p"]
["YFH1",6,0.239574,"Frataxin, regulates mitochondrial iron accumulation; interacts with Isu1p which promotes Fe-S cluster assembly; interacts with electron transport chain components and may influence respiration; human homolog involved in Friedrich's ataxia"]
["KEM1",1,0.239756,"Evolutionarily-conserved 5'-3' exonuclease component of cytoplasmic processing (P) bodies involved in mRNA decay; plays a role in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, and telomere maintenance"]
["HST1",2,0.24238,"NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and mitotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance"]
["TEC1",43,0.244003,"Transcription factor required for full Ty1 epxression, Ty1-mediated gene activation, and haploid invasive and diploid pseudohyphal growth; TEA/ATTS DNA-binding domain family member"]
["MED1",5,0.245806,"Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation"]
["CMP2",2,0.246675,"Calcineurin A; one isoform (the other is CNA1) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1"]
["SPF1",2,0.246675,"P-type ATPase, ion transporter of the ER membrane involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer toxin (SMKT) produced by Pichia farinosa KK1"]
["SPT15",4,0.25095,"TATA-binding protein, general transcription factor that interacts with other factors to form the preinitiation complex at promoters, essential for viability"]
["PBS2",6,0.254568,"MAP kinase kinase that plays a pivotal role in the osmosensing signal-transduction pathway, activated under severe osmotic stress"]
["CCR4",9,0.260551,"Component of the CCR4-NOT transcriptional complex, which is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening"]
["NRM1",1,0.263971,"Putative transcriptional repressor of MBF (MCB binding factor) target genes"]
["OPI1",13,0.266288,"Transcriptional regulator of a variety of genes; phosphorylation by protein kinase A stimulates Opi1p function in negative regulation of phospholipid biosynthetic genes; involved in telomere maintenance"]
["ELP3",4,0.27326,"Histone acetyltransferase subunit of the Elongator complex, which is a component of the RNA polymerase II holoenzyme; activity is directed specifically towards histones H3 and H4; disruption confers resistance to K. lactis zymotoxin"]
["TPK1",2,0.283329,"Subunit of cytoplasmic cAMP-dependent protein kinase, which contains redundant catalytic subunits Tpk1p, Tpk2p, and Tpk3p and regulatory subunit Bcy1p; promotes vegetative growth in response to nutrients; inhibits filamentous growth"]
["TPK3",2,0.283329,"Subunit of cytoplasmic cAMP-dependent protein kinase, which contains redundant catalytic subunits Tpk1p, Tpk2p, and Tpk3p and regulatory subunit Bcy1p; promotes vegetative growth in response to nutrients; inhibits filamentous growth"]
["LST8",2,0.283891,"Protein required for the transport of amino acid permease Gap1p from the Golgi to the cell surface; component of the TOR signaling pathway; associates with both Tor1p and Tor2p; contains a WD-repeat"]
["UBA4",2,0.283891,"Protein that activates Urm1p before its conjugation to proteins (urmylation); one target is the thioredoxin peroxidase Ahp1p, suggesting a role of urmylation in the oxidative stress response"]
["URM1",2,0.283891,"Ubiquitin-like protein with only weak sequence similarity to ubiquitin; depends on the E1-like activating enzyme Uba4p; molecular function of the Urm1p pathway is unknown, but it is required for normal growth, particularly at high temperature"]
["SAN1",3,0.285724,"Ubiquitin-protein ligase, involved in the proteasome-dependent degradation of aberrant nuclear proteins; san1 mutations suppress sir4, spt16, and cdc68 mutations, suggesting a role in chromatin silencing"]
["YHC3",2,0.289083,"Vacuolar membrane protein involved in the ATP-dependent transport of arginine into the vacuole and possibly in balancing ion homeostasis; homolog of human CLN3 involved in Batten disease (juvenile onset neuronal ceroid lipofuscinosis)"]
["SEF1",4,0.290192,"Putative transcription factor, has homolog in Kluyveromyces lactis"]
["STE50",2,0.290859,"Protein involved in mating response, invasive/filamentous growth, and osmotolerance, acts as an adaptor that links G protein-associated Cdc42p-Ste20p complex to the effector Ste11p to modulate signal transduction"]
["GIP1",1,0.291915,"Meiosis-specific regulatory subunit of the Glc7p protein phosphatase, regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p"]
["SSP2",1,0.291915,"Sporulation specific protein that localizes to the spore wall; required for sporulation at a point after meiosis II and during spore wall formation; SSP2 expression is induced midway in meiosis"]
["ESA1",4,0.29347,"Histone acetyltransferase catalytic subunit of the native multisubunit complex (NuA4) that acetylates four conserved internal lysines of histone H4 N-terminal tail; required for cell cycle progression"]
["SRB2",2,0.294002,"General transcription factor, subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; involved in telomere maintenance"]
["SEC23",1,0.294669,"GTPase-activating protein; component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat, involved in ER to Golgi transport and autophagy; stimulates the GDP-bound form of Sar1p"]
["CUP9",3,0.298555,"Homeodomain-containing transcriptional repressor of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription"]
["SKN7",24,0.308383,"Nuclear response regulator and transcription factor, part of a branched two-component signaling system; required for optimal induction of heat-shock genes in response to oxidative stress; involved in osmoregulation"]
["TRR1",1,0.30924,"Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress"]
["TSA1",1,0.30924,"Ubiquitous housekeeping thioredoxin peroxidase, reduces reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; mediates redox regulation of the nuclear localization of Yap1p; deletion results in mutator phenotype"]
["YBP1",1,0.30924,"Protein required for oxidation of specific cysteine residues of the transcription factor Yap1p, resulting in the nuclear localization of Yap1p in response to stress"]
["NAB3",1,0.309534,"Single stranded DNA binding protein; acidic ribonucleoprotein; required for termination of non-poly(A) transcripts and efficient splicing; interacts with Nrd1p"]
["NRD1",1,0.309534,"RNA-binding protein that interacts with the C-terminal domain of the RNA polymerase II large subunit (Rpo21p), required for transcription termination and 3' end maturation of nonpolyadenylated RNAs"]
["CDC48",1,0.313095,"ATPase in ER, nuclear membrane and cytosol with homology to mammalian p97; in a complex with Npl4p and Ufd1p participates in retrotranslocation of ubiquitinated proteins from the ER into the cytosol for degradation by the proteasome"]
["NMA111",1,0.313095,"Protein of unknown function which may contribute to lipid homeostasis and/or apoptosis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases"]
["NPL4",1,0.313095,"Endoplasmic reticulum and nuclear membrane protein, forms a complex with Cdc48p and Ufd1p that recognizes ubiquitinated proteins in the endoplasmic reticulum and delivers them to the proteasome for degradation"]
["SPT23",1,0.313095,"ER membrane protein involved, with its homolog Mga2p, in regulation of OLE1 transcription; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting"]
["UFD1",1,0.313095,"Protein that interacts with Cdc48p and Npl4p, involved in recognition of polyubiquitinated proteins and their presentation to the 26S proteasome for degradation; involved in transporting proteins from the ER to the cytosol"]
["SPT8",2,0.31798,"Subunit of the SAGA transcriptional regulatory complex but not present in SAGA-like complex SLIK/SALSA, required for SAGA-mediated inhibition at some promoters"]
["SPT3",9,0.325741,"Subunit of the SAGA and SAGA-like transcriptional regulatory complexes, interacts with Spt15p to activate transcription of some RNA polymerase II-dependent genes, also functions to inhibit transcription at some promoters"]
["NGG1",4,0.326419,"Transcriptional regulator involved in glucose repression of Gal4p-regulated genes; component of transcriptional adaptor and histone acetyltransferase complexes, the ADA complex, the SAGA complex, and the SLIK complex"]
["RPM2",6,0.330732,"Protein component of mitochondrial RNase P, along with the mitochondrially-encoded RNA subunit RPM1; Rnase P removes 5' extensions from tRNA precursors; Rpm2p is also involved in maturation of RPM1 and in translation of mitochondrial mRNAs"]
["NOT5",4,0.331692,"Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation"]
["BNI1",1,0.331698,"Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNR1"]
["DFG5",1,0.332185,"Putative mannosidase, essential glycosylphosphatidylinositol (GPI)-anchored membrane protein required for cell wall biogenesis in bud formation, involved in filamentous growth, homologous to Dcw1p"]
["FZF1",1,0.333131,"Transcription factor involved in sulfite metabolism, sole identified regulatory target is SSU1, overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers"]
["PHO2",24,0.338722,"Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction with Pho4p"]
["CDC42",3,0.339435,"Small rho-like GTPase, essential for establishment and maintenance of cell polarity; mutants have defects in the organization of actin and septins"]
["CLN3",6,0.342431,"G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote the G1 to S phase transition; plays a role in regulating transcription of the other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis"]
["RSC1",9,0.343887,"One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; required for expression of mid-late sporulation-specific genes; contains two essential  bromodomains, a bromo-adjacent homology (BAH) domain, and an AT hook"]
["SPT5",2,0.345124,"Protein that forms a complex with Spt4p and mediates both activation and inhibition of transcription elongation; Spt4p-Spt5p complex also plays a role in pre-mRNA processing"]
["TAF12",15,0.347242,"Subunit (61/68 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A"]
["GCN5",19,0.347332,"Histone acetyltransferase, acetylates lysine 14 on histone H3; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily"]
["GCR2",7,0.349686,"Transcriptional activator of genes involved in glycolysis; interacts and functions with the DNA-binding protein Gcr1p"]
["SNF5",7,0.351367,"Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf6p"]
["YGL007W",1,0.353815,{"$error":"#N/A"}]
["YGR154C",10,0.355719,{"$error":"#N/A"}]
["SIT4",4,0.355824,"Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization"]
["IRA1",2,0.35661,"GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, mediates membrane association of adenylate cyclase"]
["SFL1",2,0.35661,"Transcription repressor involved in regulation of flocculation-related genes, inhibits transcription by recruiting general corepressor Cyc8p-Tup1p to different promoters; negatively regulated by cAMP-dependent protein kinase A subunit Tpk2p"]
["SPT7",6,0.361263,"Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complex"]
["SNF6",2,0.364806,"Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p"]
["TYE7",1,0.368143,"Serine-rich protein that contains a basic-helix-loop-helix (bHLH) DNA binding motif; binds E-boxes of glycolytic genes and contributes to their activation; may function as a transcriptional activator in Ty1-mediated gene expression"]
["CDC47",4,0.370008,"Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase"]
["RGT1",8,0.37662,"Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose; binds to promoters and acts both as a transcriptional activator and repressor"]
["DID4",1,0.387428,"Class E Vps protein of the ESCRT-III complex, required for sorting of integral membrane proteins into lumenal vesicles of multivesicular bodies, and for delivery of newly synthesized vacuolar enzymes to the vacuole, involved in endocytosis"]
["VPS4",1,0.387428,"AAA-type ATPase required for efficient late endosome to vacuole transport; catalyzes the release of an endosomal membrane-associated class E VPS protein complex; cytoplasmic protein that is also associated with an endosomal compartment"]
["RNT1",4,0.387489,"RNAase III; cleaves a stem-loop structure at the 3' end of U2 snRNA to ensure formation of the correct U2 3' end"]
["MDH1",1,0.388323,"Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle"]
["RAS2",20,0.38869,"GTP-binding protein that regulates the nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes"]
["IRA2",3,0.38902,"GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin"]
["NDT80",1,0.390256,"Meiosis-specific transcription factor required for exit from pachytene and for full meiotic recombination; activates middle sporulation genes; competes with Sum1p for binding to promoters containing middle sporulation elements (MSE)"]
["VID30",10,0.390838,"Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); shifts the balance of nitrogen metabolism toward the production of glutamate; localized to the nucleus and the cytoplasm"]
["ACA1",1,0.392195,"Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, may regulate transcription of genes involved in utilization of non-optimal carbon sources"]
["CST6",1,0.392195,"Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, activates transcription of genes involved in utilization of non-optimal carbon sources; involved in telomere maintenance"]
["MED2",12,0.393684,"Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation"]
["STE12",71,0.395942,"Transcription factor that is activated by a MAP kinase signaling cascade, activates genes involved in mating or pseudohyphal/invasive growth pathways; cooperates with Tec1p transcription factor to regulate genes specific for invasive growth"]
["PAF1",15,0.396739,"RNA polymerase II-associated protein, defines a large complex that is biochemically and functionally distinct from the Srb-Mediator form of Pol II holoenzyme and is required for full expression of a subset of cell cycle-regulated genes"]
["CSR2",1,0.396934,"Nuclear protein with a potential regulatory role in utilization of galactose and nonfermentable carbon sources; overproduction suppresses the lethality at high temperature of a chs5 spa2 double null mutation; potential Cdc28p substrate"]
["PGD1",11,0.397598,"Subunit of the Mediator global transcriptional cofactor complex, which is part of the RNA polymerase II holoenzyme and plays an essential role in basal and activated transcription; direct target of the Cyc8p-Tup1p transcriptional corepressor"]
["RPH1",1,0.40014,"Transcriptional repressor of PHR1, which is a photolyase induced by DNA damage; binds to AG(4) (C(4)T) sequence upstream of PHR1; Rph1p phosphorylation during DNA damage is under control of the MEC1-RAD53 pathway"]
["POP2",5,0.404563,"RNase of the DEDD superfamily, subunit of the Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation"]
["DAT1",1,0.406611,"DNA binding protein that recognizes oligo(dA).oligo(dT) tracts; Arg side chain in its N-terminal pentad Gly-Arg-Lys-Pro-Gly repeat is required for DNA-binding; not essential for viability"]
["SSA1",2,0.410951,"ATPase involved in protein folding and nuclear localization signal (NLS)-directed nuclear transport; member of heat shock protein 70 (HSP70) family; forms a chaperone complex with Ydj1p; localized to the nucleus, cytoplasm, and cell wall"]
["EAF3",3,0.412517,"Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase complex, homologous to Drosophila dosage compensation protein MSL3"]
["HAL9",2,0.416231,"Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decreases both salt tolerance and ENA1 expression"]
["RDR1",2,0.416231,"Transcriptional repressor involved in the control of multidrug resistance; negatively regulates expression of the PDR5 gene; member of the Gal4p family of zinc cluster proteins"]
["RDS2",2,0.416231,"Zinc cluster protein involved in conferring resistance to ketoconazole"]
["RIM9",2,0.417546,"Protein of unknown function, involved in the proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans PalI; putative membrane protein"]
["CAM1",1,0.418662,"Translational cofactor elongation factor-1 gamma, participates in the regulation of GTP-binding protein EF-1 alpha, may play a redundant role in the regulation of protein synthesis or another GTP-dependent process"]
["TRX1",1,0.418662,"Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against both oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance"]
["CRZ1",5,0.418877,"Transcription factor that activates transcription of genes involved in stress response; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation"]
["STO1",3,0.419162,"Large subunit of the nuclear mRNA cap-binding protein complex, interacts with Npl3p to carry nuclear poly(A)+ mRNA to cytoplasm; also involved in nuclear mRNA degradation and telomere maintenance; orthologous to mammalian CBP80"]
["MBF1",2,0.422235,"Transcriptional coactivator that bridges the DNA-binding region of Gcn4p and TATA-binding protein Spt15p; suppressor of frameshift mutations"]
["CDC50",1,0.422536,"Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p"]
["HSP82",1,0.422536,"Cytoplasmic chaperone (Hsp90 family) required for pheromone signaling and negative regulation of Hsf1p; docks with the mitochondrial import receptor Tom70p for preprotein delivery; interacts with co-chaperones Cns1p, Cpr6p, Cpr7p, and Sti1p"]
["TAF1",6,0.423283,"TFIID subunit (145 kDa), involved in RNA polymerase II transcription initiation, has histone acetyltransferase activity, involved in promoter binding and G1/S progression"]
["RGT2",6,0.425675,"Plasma membrane glucose receptor, highly similar to Snf3p; both Rgt2p and Snf3p serve as transmembrane glucose sensors generating an intracellular signal that induces expression of glucose transporter (HXT) genes"]
["STE7",43,0.427343,"Signal transducing MAP kinase kinase involved in pheromone response, where it phosphorylates Fus3p, and in the pseudohyphal/invasive growth pathway, through phosphorylation of Kss1p; phosphorylated by Ste11p, degraded by ubiquitin pathway"]
["VPS24",2,0.428585,"One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); forms an ESCRT-III subcomplex with Did4p; involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway"]
["RSC3",5,0.42884,"One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; essential gene required for regulation of ribosomal protein genes and the cell wall/stress response; highly similar to Rsc30p"]
["MET4",13,0.430924,"Lecine-zipper transcriptional activator, responsible for the regulation of the sulfur amino acid pathway, requires different combinations of the auxiliary factors Cbf1p, Met28p, Met31p and Met32p"]
["SRB5",2,0.432845,"Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in telomere maintenance"]
["HSF1",37,0.432941,"Trimeric heat shock transcription factor, activates multiple genes in response to hyperthermia; recognizes variable heat shock elements (HSEs) consisting of inverted NGAAN repeats; constitutively DNA-bound; posttranslationally regulated"]
["PPR1",4,0.432945,"Zinc finger transcription factor containing a Zn(2)-Cys(6) binuclear cluster domain, positively regulates transcription of genes involved in uracil biosynthesis; activity may be modulated by interaction with Tup1p"]
["IWS1",8,0.434819,{"$error":"#N/A"}]
["MAL33",1,0.435234,"MAL-activator protein, part of complex locus MAL3; nonfunctional in genomic reference strain S288C"]
["MED6",5,0.436042,"Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation"]
["RGR1",5,0.436042,"Component of RNA polymerase II holoenzyme/mediator complex; affects chromatin structure and transcriptional regulation of diverse genes; required for glucose repression, HO repression, RME1 repression and sporulation"]
["BAS1",16,0.436358,"Myb-related transcription factor involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways"]
["SIP4",1,0.442175,"C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus"]
["CIN5",3,0.447935,"Basic leucine zipper transcriptional factor of the yAP-1 family that mediates pleiotropic drug resistance and salt tolerance; localizes constitutively to the nucleus"]
["ALPHA2",8,0.450832,{"$error":"#N/A"}]
["RSC2",9,0.453266,"One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; required for expression of mid-late sporulation-specific genes; involved in telomere maintenance"]
["HMG1",2,0.456124,"One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; localizes to the nuclear envelope; overproduction induces the formation of karmellae"]
["CNA1",3,0.45662,"Calcineurin A; one isoform (the other is CMP2) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1"]
["CNB1",3,0.45662,"Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is encoded by CNA1 and/or CMP1"]
["BCY1",1,0.460384,"Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA), a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation"]
["SPT4",3,0.466856,"Protein that forms a complex with Spt5p and mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing; in addition, Spt4p is involved in kinetochore function and gene silencing"]
["PHO80",3,0.472105,"Cyclin, negatively regulates phosphate metabolism; Pho80p-Pho85p (cyclin-CDK complex) phosphorylates Pho4p and Swi5p; deletion of PHO80 leads to aminoglycoside supersensitivity; truncated form of PHO80 affects vacuole inheritance"]
["GRR1",6,0.472784,"F-box protein component of the SCF ubiquitin-ligase complex, required for Cln1p and Cln2p degradation; involved in carbon catabolite repression, glucose-dependent divalent cation transport, high-affinity glucose transport, and morphogenesis"]
["DDC1",1,0.474989,"DNA damage checkpoint protein, part of a PCNA-like complex required for DNA damage response, required for pachytene checkpoint to inhibit cell cycle in response to unrepaired recombination intermediates; potential Cdc28p substrate"]
["FBP1",1,0.474989,"Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism"]
["PLC1",4,0.480465,"Phosphoinositide-specific phospholipase C, hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in kinetochore function and pseudohyphal differentiation"]
["RPI1",4,0.48126,"Putative transcriptional regulator; overexpression suppresses the heat shock sensitivity of wild-type RAS2 overexpression and also suppresses the cell lysis defect of an mpk1 mutation"]
["SET2",1,0.48188,"Histone methyltransferase with a role in transcriptional elongation, methylates a lysine residue of histone H3; associates with the C-terminal domain of Rpo21p; histone methylation activity is regulated by phosphorylation status of Rpo21p"]
["CHA4",2,0.487133,"DNA binding transcriptional activator, mediates serine/threonine activation of the catabolic L-serine (L-threonine) deaminase (CHA1); Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear cluster domain"]
["DHH1",5,0.488149,"Cytoplasmic DExD/H-box helicase, stimulates mRNA decapping, coordinates distinct steps in mRNA function and decay, interacts with both the decapping and deadenylase complexes, may have a role in mRNA export and translation"]
["SPT14",3,0.493823,"UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosphatidylinositol (GPI) biosynthesis, mutations cause defects in transcription and in biogenesis of cell wall proteins"]
["ROX3",6,0.496186,"RNA polymerase II holoenzyme component"]
["IME4",1,0.496656,"Probable mRNA N6-adenosine methyltransferase that is required for IME1 transcript accumulation and for sporulation; expression is induced in starved MATa/MAT alpha diploid cells"]
["MCK1",1,0.496656,"Protein serine/threonine/tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; related to mammalian glycogen synthase kinases of the GSK-3 family"]
["RIM13",1,0.496656,"Calpain-like protease involved in proteolytic activation of Ri0m101p in response to alkaline pH; has similarity to A. nidulans palB"]
["RPN1",1,0.496656,"Non-ATPase base subunit of the 19S regulatory particle of the 26S proteasome; may participate in the recognition of several ligands of the proteasome; contains a leucine-rich repeat (LRR) domain, a site for protein?protein interactions"]
["TPS1",1,0.496656,"Synthase subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway"]
["SPT16",14,0.501436,"Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure"]
["MNN4",1,0.501613,"Putative positive regulator of mannosylphosphate transferase (Mnn6p), involved in mannosylphosphorylation of N-linked oligosaccharides; expression increases in late-logarithmic and stationary growth phases"]
["CBF1",13,0.501942,"Helix-loop-helix protein that binds the motif CACRTG, which is present at several sites including MET gene promoters and centromere DNA element I (CDEI); required for nucleosome positioning at this motif; targets Isw1p to DNA"]
["FKH1",1,0.503903,"Transcription factor of the forkhead family that regulates the cell cycle and pseudohyphal growth; also involved in chromatin silencing at HML and HMR"]
["FKH2",1,0.503903,"Transcription factor of the forkhead family that regulates the cell cycle and pseudohyphal growth; also involved in chromatin silencing at HML and HMR; potential Cdc28p substrate"]
["SSK1",1,0.505768,"Cytoplasmic response regulator, part of a two-component signal transducer that mediates osmosensing via a phosphorelay mechanism; dephosphorylated form is degraded by the ubiquitin-proteasome system; potential Cdc28p substrate"]
["SOK2",2,0.506598,"Nuclear protein that plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway; negatively regulates pseudohyphal differentiation; homologous to several transcription factors"]
["CDS1",1,0.509376,"Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); an enzyme that catalyzes that conversion of CTP + phosphate into diphosphate + CDP-diaclglyerol, a critical step in the synthesis of all major yeast phospholipids"]
["ACC1",1,0.512548,"Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids"]
["ADE2",1,0.512548,"Phosphoribosylaminoimidazole carboxylase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway; red pigment accumulates in mutant cells deprived of adenine"]
["ADO1",1,0.512548,"Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle"]
["AFG3",1,0.512548,"Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes"]
["ALT1",1,0.512548,"Putative alanine transaminase (glutamic pyruvic transaminase)"]
["ARO2",1,0.512548,"Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids"]
["ARP8",1,0.512548,"Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes"]
["ASC1",1,0.512548,"WD repeat protein (G-beta like protein) involved in translation regulation; required for repression of Gcn4p activity in the absence of amino-acid starvation; core component of the ribosome; ortholog of mammalian RACK1"]
["ASF1",1,0.512548,"Nucleosome assembly factor, involved in chromatin assembly after DNA replication, anti-silencing protein that causes derepression of silent loci when overexpressed"]
["ATG11",1,0.512548,"Peripheral membrane protein required for delivery of aminopeptidase I (Lap4p) to the vacuole in the cytoplasm-to-vacuole targeting pathway; also required for peroxisomal degradation (pexophagy)"]
["ATG5",1,0.512548,"Conserved autophagy-related protein that undergoes conjugation with Atg12p and then associates with Atg16p to form a cytosolic complex essential for autophagosome formation"]
["BUD31",1,0.512548,"Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern"]
["DOM34",1,0.512548,"Probable RNA-binding protein, functions in protein translation to promote G1 progression and differentiation, required for meiotic cell division"]
["FRE2",1,0.512548,"Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low iron levels but not by low copper levels"]
["FUM1",1,0.512548,"Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial localization determined by the N-terminal mitochondrial targeting sequence and protein conformation"]
["FUR4",1,0.512548,"Uracil permease, localized to the plasma membrane; expression is tightly regulated by uracil levels and environmental cues"]
["HIT1",1,0.512548,"Protein of unknown function, required for growth at high temperature"]
["HTL1",1,0.512548,"Subunit of the RSC chromatin remodeling complex, a multisubunit complex that functions in transcriptional regulation, chromosome stability and establishing sister chromatid cohesion; involved in telomere maintenance"]
["KEX2",1,0.512548,"Subtilisin-like protease (proprotein convertase), a calcium-dependent serine protease involved in the activation of proproteins of the secretory pathway"]
["MET18",1,0.512548,"DNA repair and TFIIH regulator, required for both nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription; involved in telomere maintenance"]
["MON1",1,0.512548,"Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; associates, as a complex with Ccz1p, with a perivacuolar compartment; potential Cdc28p substrate"]
["MUB1",1,0.512548,"Protein of unknown function, deletion causes multi-budding phenotype; has similarity to Aspergillus nidulans samB gene"]
["NIS1",1,0.512548,"Protein localized in the bud neck at G2/M phase; physically interacts with septins; possibly involved in a mitotic signaling network"]
["OCA1",1,0.512548,"Putative protein tyrosine phosphatase, required for cell cycle arrest in response to oxidative damage of DNA"]
["OPI3",1,0.512548,"Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), catalyzes the last two steps in phosphatidylcholine biosynthesis"]
["PAC10",1,0.512548,"Part of the heteromeric co-chaperone GimC/prefoldin complex, which promotes efficient protein folding"]
["PDE2",1,0.512548,"High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon"]
["PHO23",1,0.512548,"Probable component of the Rpd3 histone deacetylase complex, involved in transcriptional regulation of PHO5; C-terminus has similarity to human candidate tumor suppressor p33(ING1)"]
["PHO81",1,0.512548,"Cyclin-dependent kinase (CDK) inhibitor, regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; required for derepression of PHO5; transcriptionally regulated by Pho4p and Pho2p"]
["PHO84",1,0.512548,"High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p"]
["PHO86",1,0.512548,"Endoplasmic reticulum (ER) resident protein required for ER exit of the high-affinity phosphate transporter Pho84p, specifically required for packaging of Pho84p into COPII vesicles"]
["PIB1",1,0.512548,"RING-type ubiquitin ligase of the endosomal and vacuolar membranes, binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain"]
["PIL1",1,0.512548,"Integral membrane protein that along with Lsp1p is a primary component of eisosomes, large immobile patch structures at the cell cortex associated with endocytosis; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways"]
["PSK1",1,0.512548,"One of two (see also PSK2) PAS domain containing S/T protein kinases; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status"]
["RHO4",1,0.512548,"Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely to be involved in the establishment of cell polarity"]
["RIB1",1,0.512548,"GTP cyclohydrolase II; catalyzes the first step of the riboflavin biosynthesis pathway"]
["RPL2A",1,0.512548,"Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and has similarity to E. coli L2 and rat L8 ribosomal proteins"]
["SAL6",1,0.512548,{"$error":"#N/A"}]
["TPS2",1,0.512548,"Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway"]
["TSP1",1,0.512548,{"$error":"#N/A"}]
["VHS1",1,0.512548,"Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; homolog of Sks1p"]
["VPS66",1,0.512548,"Cytoplasmic protein of unknown function involved in vacuolar protein sorting."]
["YAL004W",1,0.512548,{"$error":"#N/A"}]
["YBL094C",1,0.512548,{"$error":"#N/A"}]
["YBR147W",1,0.512548,{"$error":"#N/A"}]
["YDR537C",1,0.512548,{"$error":"#N/A"}]
["YJL211C",1,0.512548,{"$error":"#N/A"}]
["YKL169C",1,0.512548,{"$error":"#N/A"}]
["YLL007C",1,0.512548,{"$error":"#N/A"}]
["YLR414C",1,0.512548,{"$error":"#N/A"}]
["YNL120C",1,0.512548,{"$error":"#N/A"}]
["YNL276C",1,0.512548,{"$error":"#N/A"}]
["YOR331C",1,0.512548,{"$error":"#N/A"}]
["YPL162C",1,0.512548,{"$error":"#N/A"}]
["YSR3",1,0.512548,"Dihydrosphingosine 1-phosphate phosphatase, membrane protein involved in sphingolipid metabolism; has similarity to Lcb3p"]
["HPR1",5,0.5138,"Subunit of THO/TREX complexes that couple transcription elongation with mitotic recombination and with mRNA metabolism and export, subunit of an RNA Pol II complex; regulates lifespan; involved in telomere maintenance; similar to Top1p"]
["MET2",1,0.514464,"L-homoserine-O-acetyltransferase, catalyzes the conversion of homoserine to O-acetyl homoserine which is the first step of the methionine biosynthetic pathway"]
["MTM1",1,0.518388,"Mitochondrial protein of the mitochondrial carrier family, involved in activating mitochondrial Sod2p probably by facilitating insertion of an essential manganese cofactor"]
["SOD1",2,0.518536,"Cu, Zn superoxide dismutase; some mutations are analogous to those that cause ALS (amyotrophic lateral sclerosis) in humans"]
["SIN4",27,0.520506,"Subunit of the Mediator complex; interacts with the RNA polymerase II holoenzyme to postively or negatively regulate transcription; dispensible for basal transcription"]
["SUT1",1,0.521676,"Transcription factor of the Zn[II]2Cys6 family involved in sterol uptake; involved in induction of hypoxic gene expression"]
["REC104",2,0.528475,"Protein involved in early stages of meiotic recombination; required for meiotic crossing over; forms a complex with Rec102p and Spo11p necessary during the initiation of recombination"]
["CAF130",1,0.528596,"Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation"]
["CAF17",1,0.528596,"Mitochondrial protein that interacts with Ccr4p in the two-hybrid system; 3'-untranslated region contains a putative mRNA localization element common to genes encoding mitochondrial proteins"]
["CAF40",1,0.528596,"Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling mRNA initiation, elongation and degradation; binds Cdc39p"]
["DBF2",1,0.528596,"Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis"]
["TAF14",1,0.528596,"Subunit (30 kDa) of TFIID, TFIIF, and SWI/SNF complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, contains a YEATS domain"]
["GGA1",1,0.530267,"Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi"]
["GGA2",1,0.530267,"Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi"]
["RSF2",1,0.53443,"Zinc-finger protein involved in transcriptional control of both nuclear and mitochondrial genes, many of which specify products required for glycerol-based growth, respiration, and other functions"]
["SWI3",4,0.535257,"Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2"]
["LEU2",1,0.535949,"Beta-isopropylmalate dehydrogenase, catalyzes the third step in the leucine biosynthesis pathway"]
["STP2",1,0.535949,"Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes"]
["SPT20",18,0.536679,"Subunit of the SAGA transcriptional regulatory complex, involved in maintaining the integrity of the complex"]
["GAL11",14,0.538128,"Component of the Mediator complex; interacts with RNA polymerase II and the general transcription factors to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors"]
["CDC25",3,0.53902,"Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); indirectly regulates adenylate cyclase through activation of Ras1p and Ras2p by stimulating the exchange of GDP for GTP; required for progression through G1"]
["ABF1",12,0.540205,"DNA binding protein with possible chromatin-reorganizing activity involved in transcriptional activation, gene silencing, and DNA replication and repair"]
["REG1",5,0.542274,"Regulatory subunit of type 1 protein phosphatase Glc7p, involved in negative regulation of glucose-repressible genes"]
["SRB8",2,0.544433,"Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in glucose repression"]
["HMRA1",5,0.546847,"Silenced copy of a1 at HMR; homeobox corepressor that interacts with Alpha2p to repress haploid-specific gene transcription in diploid cells"]
["GUK1",1,0.549809,"Guanylate kinase, converts GMP to GDP; required for growth and mannose outer chain elongation of cell wall N-linked glycoproteins"]
["PPH22",2,0.55014,"Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis"]
["RPB9",1,0.550793,"RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site; involved in telomere maintenance"]
["TIS11",1,0.551319,"mRNA-binding protein expressed during iron starvation; binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation; involved in iron homeostasis"]
["SNF12",3,0.551695,"73 kDa subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; homolog of Rsc6p subunit of the RSC chromatin remodeling complex; deletion mutants are temperature-sensitive"]
["RME1",3,0.551776,"Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-a2 regulator; mediates cell type control of sporulation"]
["TOR1",4,0.554448,"PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis"]
["RTG1",8,0.560469,"Transcription factor (bHLH) involved in interorganelle communication between mitochondria, peroxisomes, and nucleus"]
["CAT8",8,0.561673,"Zinc cluster transcriptional activator necessary for derepression of a variety of genes under non-fermentative growth conditions, active after diauxic shift, binds carbon source responsive elements"]
["YAP1",51,0.570327,"Basic leucine zipper (bZIP) transcription factor required for oxidative stress tolerance; mediates pleiotropic drug and metal resistance; localized to the nucleus in response to the presence of oxidants"]
["HFI1",6,0.570759,"Adaptor protein required for structural integrity of the SAGA complex, a histone acetyltransferase-coactivator complex that is involved in global regulation of gene expression through acetylation and transcription functions"]
["ARG82",8,0.572076,"Protein involved in regulation of arginine-responsive and Mcm1p-dependent genes; has a dual-specificity inositol polyphosphate kinase activity required for regulation of phosphate- and nitrogen-responsive genes"]
["MET30",3,0.573125,"F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus"]
["CIT1",2,0.575429,"Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate; the rate-limiting enzyme of the TCA cycle; nuclear encoded mitochondrial protein"]
["BSD2",1,0.575493,"Heavy metal ion homeostasis protein, facilitates trafficking of Smf1p and Smf2p metal transporters to the vacuole where they are degraded, controls metal ion transport, prevents metal hyperaccumulation, functions in copper detoxification"]
["SSY1",17,0.575789,"Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes"]
["MSN1",4,0.578701,"Transcriptional activator involved in regulation of invertase and glucoamylase expression, invasive growth and pseudohyphal differentiation, iron uptake, chromium accumulation, and response to osmotic stress; localizes to the nucleus"]
["MTH1",5,0.579519,"Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation"]
["MCM1",22,0.581591,"Transcription factor involved in cell-type-specific transcription and pheromone response; plays a central role in the formation of both repressor and activator complexes"]
["PUT3",2,0.581943,"Transcriptional activator of proline utilization genes, constitutively binds PUT1 and PUT2 promoter sequences and undergoes a conformational change to form the active state; has a Zn(2)-Cys(6) binuclear cluster domain"]
["VPS20",2,0.583282,"Myristoylated subunit of ESCRTIII, the endosomal sorting complex required for transport of transmembrane proteins into the multivesicular body pathway to the lysosomal/vacuolar lumen; cytoplasmic protein recruited to endosomal membranes"]
["VPS25",2,0.583282,"Component of the ESCRT-II complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome"]
["SPT10",5,0.589172,"Putative histone acetylase, required for transcriptional regulation at core promoters, functions at or near the TATA box"]
["SPT21",5,0.589172,"Protein required for normal transcription at several loci including HTA2-HTB2 and HHF2-HHT2, but not required at the other histone loci; functionally related to Spt10p; involved in telomere maintenance"]
["XBP1",5,0.590113,"Transcriptional repressor that binds to promoter sequences of the cyclin genes, CYS3, and SMF2; expression is induced by stress or starvation during mitosis, and late in meiosis; member of the Swi4p/Mbp1p family; potential Cdc28p substrate"]
["SRB9",2,0.590615,{"$error":"#N/A"}]
["RPS14A",1,0.591643,"Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Bp and similar to E. coli S11 and rat S14 ribosomal proteins"]
["RPS14B",1,0.591643,"Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Ap and similar to E. coli S11 and rat S14 ribosomal proteins"]
["IRE1",3,0.593218,"Serine-threonine kinase and endoribonuclease; transmembrane protein that initiates the unfolded protein response signal by regulating synthesis of Hac1p through HAC1 mRNA splicing"]
["SER3",1,0.595808,"3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser33p"]
["SMP1",1,0.599356,"Putative transcription factor involved in regulating the response to osmotic stress; member of the MADS-box family of transcription factors"]
["PHO85",14,0.599757,"Cyclin-dependent kinase, with ten cyclin partners; involved in environmental stress response; in phosphate-rich conditions, Pho85p-Pho80p complex phosphorylates Pho4p which in turn represses PHO5"]
["HXK1",3,0.601711,"Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p"]
["STD1",6,0.603568,"Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the transcription factor Rgt1p"]
["IME1",13,0.603844,"Master regulator of meiosis that is active only during meiotic events, activates transcription of early meiotic genes through interaction with Ume6p, degraded by the 26S proteasome following phosphorylation by Ime2p"]
["SPT6",4,0.603998,"Essential protein that interacts with histones and is involved in nucleosome disassembly and reassembly during transcription elongation"]
["PGS1",6,0.60618,"Phosphatidylglycerolphosphate synthase, catalyzes the synthesis of phosphatidylglycerolphosphate from CDP-diacylglycerol and sn-glycerol 3-phosphate in the first committed and rate-limiting step of cardiolipin biosynthesis"]
["SSN8",10,0.608492,"Cyclin-like component of the RNA polymerase II holoenzyme, involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression and telomere maintenance"]
["PDR3",13,0.609514,"Transcriptional activator of the pleiotropic drug resistance network, regulates expression of ATP-binding cassette (ABC) transporters through binding to cis-acting sites known as PDREs (PDR responsive elements)"]
["ADA2",5,0.610565,"Transcription coactivator, component of the ADA and SAGA transcriptional adaptor/HAT (histone acetyltransferase) complexes"]
["SNF3",4,0.611535,"Plasma membrane glucose sensor that regulates glucose transport; has 12 predicted transmembrane segments; long cytoplasmic C-terminal tail is required for low glucose induction of hexose transporter genes HXT2 and HXT4"]
["WHI2",1,0.614232,"Protein required, with binding partner Psr1p, for full activation of the general stress response, possibly through Msn2p dephosphorylation; regulates growth during the diauxic shift; negative regulator of G1 cyclin expression"]
["HXK2",5,0.614287,"Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene"]
["SUM1",2,0.615352,"Transcriptional repressor required for mitotic repression of middle sporulation-specific genes; involved in telomere maintenance, regulated by the pachytene checkpoint"]
["CTI6",3,0.618162,"Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recruiting the SAGA complex to the repressed promoter; contains a PHD finger domain"]
["MET31",4,0.62303,"Zinc-finger DNA-binding protein, involved in regulating expression of the methionine biosynthetic genes, similar to Met32p"]
["STE11",6,0.626331,"Signal transducing MEK kinase involved in pheromone response and pseudohyphal/invasive growth pathways, where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p"]
["SHE4",2,0.630111,"Protein containing a UCS (UNC-45/CRO1/SHE4) domain, binds to myosin motor domains to regulate myosin function; involved in endocytosis, polarization of the actin cytoskeleton, and asymmetric mRNA localization"]
["MET32",3,0.633302,"Zinc-finger DNA-binding protein, involved in regulating expression of the methionine biosynthetic genes, similar to Met31p"]
["SKO1",9,0.63574,"Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that forms a complex with Tup1p and Ssn6p to both activate and repress transcription; cytosolic and nuclear protein involved in the osmotic and oxidative stress responses"]
["CDC73",2,0.635874,"Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p, distinct from Srb-containing Pol II complexes; required for expression of certain genes, modification of some histones, and telomere maintenance"]
["SSN6",20,0.637537,{"$error":"#N/A"}]
["SWI1",17,0.638116,"Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2"]
["YAK1",2,0.638586,"Serine-threonine protein kinase that is part of a glucose-sensing system involved in growth control in response to glucose availability; translocates from the cytoplasm to the nucleus and phosphorylates Pop2p in response to a glucose signal"]
["SRB4",7,0.640189,"Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation"]
["RTG3",6,0.640566,"Basic helix-loop-helix-leucine zipper (bHLH/Zip) transcription factor that forms a complex with another bHLH/Zip protein, Rtg1p, to activate the retrograde (RTG) and TOR pathways"]
["GCN4",50,0.640885,"Transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels"]
["CAD1",1,0.644156,"AP-1-like bZIP transcriptional activator involved in multiple stress responses, iron metabolism, and pleiotropic drug resistance; controls a set of genes involved in stabilizing proteins, binds consensus sequence TTACTAA; 5' UTR contains uORFs"]
["RSC30",3,0.644418,"One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; non-essential gene required for regulation of ribosomal protein genes and the cell wall/stress response; highly similar to Rsc3p; null mutants are osmosensitive"]
["HHO1",6,0.645107,"Histone H1, a linker histone required for nucleosome packaging at restricted sites; suppresses DNA repair involving homologous recombination; not required for telomeric silencing, basal transcriptional repression, or efficient sporulation"]
["PTP2",1,0.652394,"Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the nucleus"]
["PTP3",1,0.652394,"Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm"]
["URE2",9,0.653979,"Nitrogen catabolite repression regulator that acts by inhibition of GLN3 transcription in good nitrogen source; altered form of Ure2p creates [URE3] prion"]
["CYR1",1,0.655839,"Adenylate cyclase, required for cAMP production and cAMP-dependent protein kinase signaling; involved in cell cycle control and glucose and nitrogen repression of sporulation"]
["GPB1",1,0.655839,"Proposed beta subunit of the heterotrimeric G protein that interacts with the receptor Grp1p, has signaling role in response to nutrients; involved in regulation of pseudohyphal growth through cAMP levels; homolog of Gpb2p"]
["GPB2",1,0.655839,"Proposed beta subunit of the heterotrimeric G protein that interacts with the receptor Grp1p, has signaling role in response to nutrients; involved in regulation of pseudohyphal growth through cAMP levels; homolog of Gpb1p"]
["GPG1",1,0.655839,"Proposed gamma subunit of the heterotrimeric G protein that interacts with the receptor Grp1p; involved in regulation of pseudohyphal growth; requires Gpb1p or Gpb2p to interact with Gpa2p"]
["GPR1",1,0.655839,"Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis"]
["MSS11",1,0.655839,"Transcription factor involved in regulation of invasive growth and starch degradation; controls the activation of MUC1 and STA2 in response to nutritional signals"]
["NRG2",1,0.655839,"Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p"]
["PHD1",1,0.655839,"Transcriptional activator that enhances pseudohyphal growth; regulates expression of FLO11, an adhesin required for pseudohyphal filament formation; similar to StuA, an A. nidulans developmental regulator; potential Cdc28p substrate"]
["NHP6B",1,0.662339,"High-mobility group non-histone chromatin protein, functionally redundant with Nhp6Ap; homologous to mammalian high mobility group proteins 1 and 2; acts to recruit transcription factor Rcs1p to certain promoters"]
["SET3",1,0.662339,"Defining member of the SET3 histone deacetylase complex which is a meiosis-specific repressor of sporulation genes; necessary for efficient transcription by RNAPII; one of two yeast proteins that contains both SET and PHD domains"]
["SWT1",1,0.662339,{"$error":"#N/A"}]
["JEN1",1,0.662842,"Lactate transporter, required for uptake of lactate and pyruvate; expression is derepressed by transcriptional activator Cat8p under nonfermentative growth conditions, and repressed in the presence of glucose, fructose, and mannose"]
["RAS1",2,0.664302,"GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes"]
["STP1",2,0.665082,"Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes and may have a role in tRNA processing"]
["LEU3",7,0.665437,"Zinc-finger transcription factor that regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; positively regulated by alpha-isopropylmalate, an intermediate in leucine biosynthesis"]
["PHO4",9,0.66988,"Basic helix-loop-helix (bHLH) transcription factor; binds cooperatively with Pho2p to the PHO5 promoter; function is regulated by phosphorylation at multiple sites and by phosphate availability"]
["SET1",7,0.67076,"Histone methyltransferase, subunit of the COMPASS (Set1C) complex which methylates histone H3 on lysine 4; required in transcriptional silencing near telomeres and at the silent mating type loci; contains a SET domain"]
["THG1",3,0.670926,"tRNAHis guanylyltransferase, adds a guanosine residue to the 5' end of tRNAHis after transcription and RNase P cleavage; couples nuclear division and migration to cell budding and cytokinesis; essential enzyme conserved among eukaryotes"]
["CBK1",13,0.671646,"Serine/threonine protein kinase that regulates cell morphogenesis pathways; involved in cell wall biosynthesis, apical growth, proper mating projection morphology, bipolar bud site selection in diploid cells, and cell separation"]
["SSD1",1,0.673227,"Protein with a role in maintenance of cellular integrity, interacts with components of the TOR pathway; ssd1 mutant of a clinical S. cerevisiae strain displays elevated virulence"]
["HAC1",2,0.673885,"bZIP transcription factor (ATF/CREB1 homolog) that regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway utilizing Ire1p, Trl1p and Ada5p facilitates efficient Hac1p synthesis"]
["MOT1",3,0.676693,"Essential abundant protein involved in regulation of transcription, removes Spt15p (TBP) from DNA via its C-terminal ATPase activity, forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity"]
["SSZ1",4,0.678639,"Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit; also involved in pleiotropic drug resistance via sequential activation of PDR1 and PDR5; binds ATP"]
["BPL1",2,0.682908,"Biotin:apoprotein ligase, covalently modifies proteins with the addition of biotin, required for acetyl-CoA carboxylase (Acc1p) holoenzyme formation"]
["POS5",152,0.686678,"Mitochondrial NADH kinase, phosphorylates NADH; also phosphorylates NAD(+) with lower specificity; required for the response to oxidative stress"]
["ERG24",1,0.689231,"C-14 sterol reductase, acts in ergosterol biosynthesis; mutants accumulate the abnormal sterol ignosterol (ergosta-8,14 dienol), and are viable under anaerobic growth conditions but inviable on rich medium under aerobic conditions"]
["HOG1",33,0.69527,"Mitogen-activated protein kinase involved in osmoregulation via three independent osmosensors; mediates the recruitment and activation of RNA Pol II at Hot1p-dependent promoters; localization regulated by Ptp2p and Ptp3p"]
["ASI1",1,0.695628,"Putative integral membrane E3 ubiquitin ligase; genetic interactions suggest a role in negative regulation of amino acid uptake"]
["ASI2",1,0.695628,"Predicted membrane protein; genetic interactions suggest a role in negative regulation of amino acid uptake"]
["ASI3",1,0.695628,"Putative integral membrane E3 ubiquitin ligase; genetic interactions suggest a role in negative regulation of amino acid uptake"]
["MSN2",61,0.69658,"Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression"]
["TOR2",1,0.696724,"PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis"]
["RSF1",5,0.702726,"Protein required for respiratory growth; localized to both the nucleus and mitochondrion; mutant displays decreased transcription of specific nuclear and mitochondrial genes whose products are involved in respiratory growth"]
["CUP1A",1,0.703869,{"$error":"#N/A"}]
["HTA1",1,0.703869,"One of two nearly identical (see also HTA2) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p "]
["MEP1",1,0.703869,"Ammonium permease; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation"]
["RRP6",1,0.703869,"Exonuclease component of the nuclear exosome; contributes to the quality-control system that retains and degrades aberrant mRNAs in the nucleus"]
["TFA1",1,0.703869,"TFIIE large subunit, involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening"]
["GZF3",4,0.703958,"GATA zinc finger protein and Dal80p homolog that negatively regulates nitrogen catabolic gene expression by competing with Gat1p for GATA site binding; function requires a repressive carbon source; dimerizes with Dal80p and binds to Tor1p"]
["FAU1",1,0.704767,"5,10-methenyltetrahydrofolate synthetase, involved in folic acid biosynthesis"]
["MET13",1,0.704767,"Isozyme of methylenetetrahydrofolate reductase, catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway"]
["TPK2",6,0.705871,"Subunit of cytoplasmic cAMP-dependent protein kinase, which contains redundant catalytic subunits Tpk1p, Tpk2p, and Tpk3p and regulatory subunit Bcy1p; promotes vegetative growth in response to nutrients; activates filamentous growth"]
["RIM15",5,0.710684,"Glucose-repressible protein kinase involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; originally identified as a regulator of IME2"]
["RIM101",13,0.711439,"Transcriptional repressor involved in the response to pH; required for alkaline pH-stimulated differentiation pathways such as haploid invasive growth and sporulation; activated by proteolytic processing; has similarity to the A. nidulans transcription factor PacC"]
["SEC1",2,0.711847,"Sm-like protein involved in docking and fusion of exocytic vesicles through binding to assembled SNARE complexes at the membrane; localization to sites of secretion (bud neck and bud tip) is dependent on SNARE function"]
["ASH1",6,0.713537,"Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in the distal tip of anaphase cells, resulting in accumulation of Ash1p in daughter cell nuclei and inhibition of HO expression; potential Cdc28p substrate"]
["SRB7",3,0.714794,"Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p"]
["STB5",3,0.718008,"Activator of multidrug resistance genes, forms a heterodimer with Pdr1p; contains a Zn(II)2Cys6 zinc finger domain that interacts with a PDRE (pleotropic drug resistance element) in vitro; binds Sin3p in a two-hybrid assay"]
["ARO80",2,0.718253,"Zinc finger transcriptional activator of the Zn2Cys6 family; activates transcription of aromatic amino acid catabolic genes in the presence of aromatic amino acids"]
["RHO1",2,0.719689,"GTP-binding protein of the rho subfamily of Ras-like proteins, involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p)"]
["GCD11",1,0.723249,"Gamma subunit of the translation initiation factor eIF2, involved in the identification of the start codon; binds GTP when forming the ternary complex with GTP and tRNAi-Met"]
["SUI2",1,0.723249,"Alpha subunit of the translation initiation factor eIF2, involved in the identification of the start codon; phosphorylation of Ser51 is required for regulation of translation by inhibiting the exchange of GDP for GTP"]
["RIM11",3,0.725743,"Protein kinase required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta"]
["HXT1",3,0.727131,"Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting"]
["DAL82",8,0.728835,"Positive regulator of allophanate inducible genes; binds a dodecanucleotide sequence upstream of all genes that are induced by allophanate; contains an UISALL DNA-binding, a transcriptional activation, and a coiled-coil domain"]
["FZO1",1,0.731333,"Mitochondrial integral membrane protein involved in mitochondrial fusion and maintenance of the mitochondrial genome; contains N-terminal GTPase domain"]
["OXA1",1,0.731333,"Translocase of the mitochondrial inner membrane, mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane, interacts with mitochondrial ribosomes; null is respiratory deficient"]
["RDS1",1,0.731333,"Zinc cluster protein involved in conferring resistance to cycloheximide"]
["TIM17",1,0.731333,"Essential constituent of the mitochondrial inner membrane presequence translocase; interacts with Pam18p to recruit the presequence translocase-associated motor (PAM complex) and also required for protein sorting during import"]
["GLN3",26,0.733337,"Transcriptional activator of genes regulated by nitrogen catabolite repression (NCR), localization and activity regulated by quality of nitrogen source"]
["FKS1",24,0.734271,"Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic subunit Gsc2p; binds to regulatory subunit Rho1p; involved in cell wall synthesis and maintenance; localizes to sites of cell wall remodeling"]
["GTS1",5,0.741641,"Protein containing a zinc-finger in the N-terminus and a long Gln-rich region in the C-terminus; regulates ultradian rhythm, cell size, cell cycle, lifespan, sporulation, heat tolerance, and multidrug transport"]
["ARG80",6,0.746204,"Transcription factor involved in regulation of arginine-responsive genes; acts with Arg81p and Arg82p"]
["ARG81",6,0.746204,"Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p"]
["AMA1",3,0.750807,"Activator of meiotic anaphase promoting complex (APC/C); Cdc20p family member; required for initiation of spore wall assembly; required for Clb1p degradation during meiosis"]
["FUS3",3,0.751662,"Mitogen-activated protein kinase involved in mating pheromone response; activated by phoshporylation by Ste7p; provides specificity during the mating vs. filamentous growth response by phosphorylating transcriptional and cytoplasmic targets"]
["TFA2",4,0.752696,"TFIIE small subunit, involved in RNA polymerase II transcription initiation"]
["RAD9",2,0.758576,"DNA damage-dependent checkpoint protein, required for cell-cycle arrest in G1/S, intra-S, and G2/M; transmits checkpoint signal by activating Rad53p and Chk1p; hyperphosphorylated by Mec1p and Tel1p; potential Cdc28p substrate"]
["YKU70",2,0.758576,"Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair"]
["SIR2",3,0.761985,"Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespan;  plays roles in silencing at HML, HMR, telomeres, and the rDNA locus; negatively regulates initiation of DNA replication"]
["PKC1",5,0.764832,"Protein serine/threonine kinase essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC)"]
["RFX1",5,0.765148,"Protein involved in DNA damage and replication checkpoint pathway; recruits repressors Tup1p and Cyc8p to promoters of DNA damage-inducible genes; similar to a family of mammalian DNA binding RFX1-4 proteins"]
["HTZ1",3,0.765165,"Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin"]
["PDC1",1,0.769408,"Major of three pyruvate decarboxylase isozymes, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde; subject to glucose-, ethanol-, and autoregulation; involved in amino acid catabolism"]
["PDC2",1,0.769408,"Transcription factor required for the synthesis of the glycolytic enzyme pyruvate decarboxylase, required for high level expression of both the THI and the PDC genes"]
["GCN2",2,0.769756,"Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex"]
["BDF1",9,0.772299,"Protein involved in transcription initiation at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf2p"]
["RTG2",6,0.777436,"Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcriptional activators of the retrograde (RTG) and TOR pathways; Rtg2p is inhibited by the phosphorylated form of Mks1p"]
["SSN3",11,0.783923,"Cyclin-dependent protein kinase, component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression"]
["SSU72",7,0.784003,"Transcription/RNA-processing factor that associates with TFIIB and cleavage/polyadenylation factor Pta1p; exhibits phosphatase activity on serine-5 of the RNA polymerase II C-terminal domain; affects start site selection in vivo"]
["CSE2",29,0.789654,"Component of the Med9/10 module, which is a subcomplex within the RNA polymerase II Mediator complex; required for regulation of RNA polymerase II activity"]
["LYS14",4,0.789915,"Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer"]
["CTR10",3,0.792197,{"$error":"#N/A"}]
["GAL4",13,0.793765,"DNA-binding transcription factor required for the activation of the GAL genes in response to galactose; repressed by Gal80p and activated by Gal3p"]
["HLR1",1,0.7948,"Protein involved in regulation of cell wall composition and integrity and response to osmotic stress; overproduction suppresses a lysis sensitive PKC mutation; similar to Lre1p, which functions antagonistically to protein kinase A"]
["LRE1",1,0.7948,"Protein involved in control of cell wall structure and stress response; inhibits Cbk1p protein kinase activity; overproduction confers resistance to cell-wall degrading enzymes"]
["FAS1",1,0.796103,"Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities"]
["FAS2",1,0.796103,"Alpha subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains beta-ketoacyl reductase and beta-ketoacyl synthase activities"]
["AZF1",2,0.796369,"Zinc-finger transcription factor, involved in induction of CLN3 transcription in response to glucose; genetic and physical interactions indicate a possible role in mitochondrial transcription or genome maintenance"]
["SNF4",10,0.80696,"Protein kinase activator found in a complex containing Snf1p and members of the Sip1p/Sip2p/Gal83p family; activates the Snf1p protein kinase; involved in expression of glucose-repressed genes, sporulation, and peroxisome biogenesis"]
["HDA1",12,0.8098,"Putative catalytic subunit of a class II histone deacetylase complex that also contains Hda2p and Hda3p; Hda1p interacts with the Hda2p-Hda3p subcomplex to form an active tetramer; deletion increases histone H2B, H3 and H4 acetylation"]
["MIG3",2,0.809865,"Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genes"]
["MSI1",1,0.820212,"Subunit of chromatin assembly factor I (CAF-I), regulates the RAS/cAMP pathway via sequestration of Npr1p kinase; localizes to the nucleus and cytoplasm; homologous to human retinoblastoma binding proteins RbAp48 and RbAp46"]
["PDE1",1,0.820212,"Low-affinity cyclic AMP phosphodiesterase, controls glucose and intracellular acidification-induced cAMP signaling, target of the cAMP-protein kinase A (PKA) pathway; glucose induces transcription and inhibits translation"]
["RAM1",1,0.820212,"Beta subunit of the CAAX farnesyltransferase (FTase) that prenylates the a-factor mating pheromone and Ras proteins; required for the membrane localization of Ras proteins and a-factor; homolog of the mammalian FTase beta subunit"]
["RPT1",1,0.820212,"One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and the E3 ubiquitin-protein ligase Ubr1p"]
["ROX1",25,0.821586,"Heme-dependent repressor of hypoxic genes; contains an HMG domain that is responsible for DNA bending activity"]
["MAF1",1,0.822654,"Negative regulator of RNA polymerase III; component of several signaling pathways that repress polymerase III transcription in response to changes in cellular environment; targets the initiation factor TFIIIB"]
["MKS1",6,0.822929,"Pleiotropic regulatory factor involved in Ras-CAMP and lysine biosynthetic pathways and nitrogen regulation; involved in retrograde (RTG) mitochondria-to-nucleus signaling"]
["NRG1",7,0.826004,"Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response"]
["HAA1",10,0.826106,"Transcriptional activator involved in the transcription of TPO2, HSP30 and other genes encoding membrane stress proteins; despite sequence similarity with the transcription factor Ace1p, it is not subject to metalloregulation"]
["RAD26",6,0.828881,"Protein involved in transcription-coupled repair nucleotide excision repair of UV-induced DNA lesions; homolog of human CSB protein"]
["MLH1",4,0.829537,"Protein required for mismatch repair in mitosis and meiosis, postmeiotic segregation, and spore viability; forms a complex with Pms1p and Msh2p to repair mismatched DNA; human homolog is associated with hereditary non-polyposis colon cancer"]
["FLO8",2,0.831656,"Transcription factor required for flocculation, diploid filamentous growth, and haploid invasive growth; genome reference strain S288C and most laboratory strains have a mutation in this gene"]
["IMP2_2",5,0.833888,{"$error":"#N/A"}]
["IME2",7,0.83397,"Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p"]
["PDR1",40,0.839458,"Zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes"]
["HOS2",2,0.840061,"Histone deacetylase required for gene activation via specific deacetylation of lysines in H3 and H4 histone tails; subunit of the Set3 complex, a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity"]
["SFP1",4,0.846439,"Transcription factor that controls expression of many ribosome biogenesis genes in response to nutrients and stress, regulates G2/M transitions during mitotic cell cycle and DNA-damage response, involved in cell size modulation"]
["DCS1",1,0.846904,"Non-essential hydrolase involved in mRNA decapping, may function in a feedback mechanism to regulate deadenylation, contains pyrophosphatase activity and a HIT (histidine triad) motif; interacts with neutral trehalase Nth1p"]
["NUT2",3,0.848454,"Component of the RNA polymerase II mediator complex, which is required for transcriptional activation and also has a role in basal transcription"]
["SAS2",11,0.849765,"Histone acetyltransferase (HAT) catalytic subunit of the SAS complex (Sas2p-Sas4p-Sas5p), which  acetylates free histones and nucleosomes and regulates transcriptional silencing; member of the MYSTacetyltransferase family"]
["MCD1",1,0.850392,"Essential protein required for sister chromatid cohesion in mitosis and meiosis; subunit of the cohesin complex; expression is cell cycle regulated and peaks in S phase "]
["SIR4",1,0.850392,"Silent information regulator that, together with SIR2 and SIR3, is involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci; potentially phosphorylated by Cdc28p; some alleles of SIR4 prolong lifespan"]
["KIN28",1,0.854028,"Serine/threonine protein kinase, subunit of the transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters"]
["MAG1",1,0.854028,"3-methyl-adenine DNA glycosylase involved in protecting DNA against alkylating agents; initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired"]
["NUT1",1,0.854028,"Component of the RNA polymerase II mediator complex, which is required for transcriptional activation and also has a role in basal transcription"]
["RAD18",1,0.854028,"Protein involved in postreplication repair; binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; forms heterodimer with Rad6p; contains RING-finger motif"]
["RAD2",1,0.854028,"Single-stranded DNA endonuclease, cleaves single-stranded DNA during nucleotide excision repair to excise damaged DNA; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPG protein"]
["RAD50",1,0.854028,"Subunit of MRX complex, with Mre11p and Xrs2p, involved in processing double-strand DNA breaks in vegetative cells, initiation of meiotic DSBs, telomere maintenance, and nonhomologous end joining"]
["RAD52",1,0.854028,"Protein that stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis"]
["RAD6",1,0.854028,"Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (with Rad18p), sporulation, telomere silencing, and ubiquitin-mediated N-end rule protein degradation (with Ubr1p)"]
["RPO21",1,0.854028,"RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime"]
["FAB1",1,0.854804,"1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis"]
["SCH9",1,0.854804,"Protein kinase that regulates signal transduction activity and G1 progression, controls cAPK activity, required for nitrogen activation of the FGM pathway, involved in life span regulation, homologous to mammalian Akt/PKB"]
["TAF5",1,0.854804,"Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification"]
["VPS34",1,0.854804,"Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; similar to p110 subunit of mammalian PI 3-kinase"]
["GAS1",6,0.855417,"Beta-1.3-glucanosyltransferase, required for cell wall assembly; localizes to the cell surface via a glycosylphosphatidylinositol (GPI) anchor"]
["MSN4",56,0.857245,"Transcriptional activator related to Msn2p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression"]
["SWI5",21,0.863999,"Transcription factor that activates transcription of genes expressed in G1 phase and at the G1/M boundary; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase"]
["UGA3",3,0.86407,"Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes (such as UGA1, UGA2, UGA4); zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type; localized to the nucleus"]
["SNF1",24,0.865646,"AMP-activated serine/threonine protein kinase found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis"]
["DST1",3,0.87114,"General transcription elongation factor TFIIS, enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites"]
["RPT4",3,0.875696,"One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for spindle pole body duplication; localized mainly to the nucleus throughout the cell cycle"]
["TUP1",46,0.876593,"General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes"]
["DAL80",21,0.880038,"Negative regulator of genes in multiple nitrogen degradation pathways; expression is regulated by nitrogen levels and by Gln3p; member of the GATA-binding family, forms homodimers and heterodimers with Deh1p"]
["NFS1",2,0.886024,"Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria"]
["SIR3",14,0.88645,"Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tails, to establish a transcriptionally silent chromatin state; required for spreading of silenced chromatin; recruited to chromatin through interaction with Rap1p"]
["GPA2",3,0.887022,"Nucleotide binding alpha subunit of the heterotrimeric G protein that interacts with the receptor Gpr1p, has signaling role in response to nutrients; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery"]
["RLM1",25,0.900248,"MADS-box transcription factor, component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p"]
["MOB2",10,0.901584,"Component of the RAM signaling network, localizes and activates the Ace2p in the daughter cell nucleus to direct daughter cell-specific transcription of several genes involved in cell separation; Mob1p-like protein"]
["SNF2",25,0.901807,"Catalytic subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; contains DNA-stimulated ATPase activity; functions interdependently in transcriptional activation with Snf5p and Snf6p"]
["DAL81",12,0.902241,"Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism"]
["PHO90",3,0.902424,"Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth"]
["RFA1",6,0.903883,"Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination"]
["RFA3",6,0.903883,"Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination"]
["MFA1",1,0.90489,"Mating pheromone a-factor, made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA2"]
["MFA2",1,0.90489,"Mating pheromone a-factor, made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA1"]
["MFALPHA1",1,0.90489,{"$error":"#N/A"}]
["MFALPHA2",1,0.90489,{"$error":"#N/A"}]
["RFA2",9,0.907475,"Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination"]
["IXR1",3,0.909734,"Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b"]
["RDS3",2,0.912181,"Zinc cluster protein involved in pre-mRNA splicing and cycloheximide resistance"]
["GAL80",7,0.915577,"Transcriptional regulator involved in the repression of GAL genes in the absence of galactose; inhibits transcriptional activation by Gal4p; inhibition relieved by Gal3p or Gal1p binding"]
["RIM4",5,0.917313,"Putative RNA-binding protein required for the expression of early and middle sporulation genes"]
["RPD3",18,0.918929,"Histone deacetylase; regulates transcription and silencing"]
["INO2",30,0.923485,"Component of the heteromeric Ino2p/Ino4p basic helix-loop-helix transcription activator that binds inositol/choline-responsive elements (ICREs), required for derepression of phospholipid biosynthetic genes in response to inositol depletion"]
["AFT2",3,0.925895,"Iron-regulated transcriptional activator, required for iron homeostasis and resistance to oxidative stress; similar to Aft1p"]
["RPT6",4,0.927681,"One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle"]
["PIP2",24,0.936047,"Autoregulatory oleate-specific transcriptional activator of peroxisome proliferation, contains Zn(2)-Cys(6) cluster domain, forms heterodimer with Oaf1p, binds oleate response elements (OREs), activates beta-oxidation genes"]
["GAL3",4,0.938115,"Transcriptional regulator involved in activation of the GAL genes in response to galactose; forms a complex with Gal80p and Gal4p to relieve inhibition by Gal80p; binds galactose and ATP but does not have galactokinase activity"]
["ALPHA1",2,0.940676,{"$error":"#N/A"}]
["PHO87",2,0.941001,"Low-affinity inorganic phosphate (Pi) transporter, involved in activation of PHO pathway; expression is independent of Pi concentration and Pho4p activity; contains 12 membrane-spanning segments"]
["PHO91",2,0.941001,"Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth"]
["KTI11",1,0.941829,"Protein required, along with Dph1p, Dph2p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph1p and Dph2p"]
["ECM22",5,0.943142,"Sterol regulatory element binding protein, regulates transcription of the sterol biosynthetic genes ERG2 and ERG3; member of the fungus-specific Zn[2]-Cys[6] binuclear cluster family of transcription factors; homologous to Upc2p"]
["SIN3",18,0.947812,"DNA binding subunit of Sin3p-Rpd3p histone deacetylase complex, involved in transcriptional repression of meiosis-specific genes during vegetative growth and silencing; involved in telomere maintenance"]
["OAF1",24,0.948892,"Oleate-activated transcription factor, acts alone and as a heterodimer with Pip2p; activates genes involved in beta-oxidation of fatty acids and peroxisome organization and biogenesis"]
["CAT5",3,0.949522,"Mitochondrial inner membrane protein directly involved in ubiquinone biosynthesis, essential for several other metabolic pathways including respiration and gluconeogenic gene activation"]
["YRR1",16,0.955763,"Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrm1p, acting on an overlapping set of target genes"]
["RAD53",2,0.957785,"Protein kinase, required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p"]
["ISW2",5,0.957997,"Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase component that, with Itc1p, forms a complex required for repression of a-specific genes, INO1, and early meiotic genes during mitotic growth"]
["ITC1",5,0.957997,"Component of the ATP-dependent Isw2p-Itc1p chromatin remodeling complex, required for repression of a-specific genes, repression of early meiotic genes during mitotic growth, and repression of INO1"]
["ADR1",11,0.963005,"Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization"]
["MIG2",12,0.965098,"Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter"]
["MIG1",24,0.965219,"Transcription factor involved in glucose repression; C2H2 zinc finger protein similar to mammalian Egr and Wilms tumor proteins"]
["UME6",37,0.966386,"Key transcriptional regulator of early meiotic genes, binds URS1 upstream regulatory sequence, couples metabolic responses to nutritional cues with initiation and progression of meiosis, forms complex with Ime1p, and also with Sin3p-Rpd3p"]
["ACE2",21,0.974907,"Transcription factor that activates expression of early G1-specific genes, localizes to daughter cell nuclei after cytokinesis and delays G1 progression in daughters, localization is regulated by phosphorylation; potential Cdc28p substrate"]
["SLT2",14,0.980136,"Serine/threonine MAP kinase involved in regulating the maintenance of cell wall integrity and progression through the cell cycle; regulated by the PKC1-mediated signaling pathway"]
["FHL1",1,0.981654,"Putative transcriptional regulator with similarity to DNA-binding domain of Drosophila forkhead; required for rRNA processing"]
["INO4",31,0.982432,"Transcription factor required for derepression of inositol-choline-regulated genes involved in phospholipid synthesis; forms a complex, with Ino2p, that binds the inositol-choline-responsive element through a basic helix-loop-helix domain"]
["IFH1",10,0.983498,"Essential protein with a highly acidic N-terminal domain; IFH1 exhibits genetic interactions with FHL1, overexpression interferes with silencing at telomeres and HM loci; potential Cdc28p substrate"]
["KOG1",1,0.985159,"Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors"]
["EDC1",2,0.985254,"RNA-binding protein, activates mRNA decapping directly by binding to the mRNA substrate and enhancing the activity of the decapping proteins Dcp1p and Dcp2p"]
["WAR1",1,0.986596,"Homodimeric Zn2Cys6 zinc finger transcription factor; binds to a weak acid response element to induce transcription of PDR12 and FUN34, encoding an acid transporter and a putative ammonia transporter, respectively"]
["HEM1",2,0.987042,"5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p"]
["UPC2",16,0.989882,"Sterol regulatory element binding protein, induces transcription of sterol transport and biosynthetic genes; involved in the anaerobic induction of DAN/TIR mannoproteins and seripauperins; binucleate zinc cluster protein; Ecm22p homolog"]
["RCS1",21,0.991301,"Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability"]
["PPZ1",6,0.992103,"Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance"]
["PPZ2",6,0.992103,"Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance"]
["BMH1",2,0.992236,"14-3-3 protein, major isoform; binds proteins and DNA, involved in regulation of many processes including exocytosis and vesicle transport, Ras/MAPK signaling during pseudohyphal development, rapamycin-sensitive signaling, and others"]
["BMH2",2,0.992236,"14-3-3 protein, minor isoform; binds proteins and DNA, involved in regulation of many processes including exocytosis and vesicle transport, Ras/MAPK signaling during pseudohyphal development, rapamycin-sensitive signaling, and others"]
["SMP2",3,0.999425,"Mg<sup>2+</sup>-dependent phosphatidate (PA) phosphatase, catalyzes the dephosphorylation of PA to yield diacylglycerol and P<sub>i</sub>, responsible for de novo lipid synthesis; homologous to mammalian lipin 1"]

{"sheet":"Reporter-GOs","index":1,"n_rows":2641,"n_cols":5,"rows_kept":2641,"flags":["formulas_cached_only"]}
["Complete list of reporter GO"]
[]
["GO-ID","GO term","Process/Function/Component","Number of neighbors","P-value"]
["GO:0005730","nucleolus","C",148,7.25127e-10]
["GO:0045324","late endosome to vacuole transport","P",16,0.000137909]
["GO:0030490","processing of 20S pre-rRNA","P",46,0.000180327]
["GO:0005732","small nucleolar ribonucleoprotein complex","C",55,0.000870868]
["GO:0006365","35S primary transcript processing","P",64,0.00108615]
["GO:0006364","rRNA processing","P",58,0.00119803]
["GO:0005681","spliceosome complex","C",29,0.00152346]
["GO:0006511","ubiquitin-dependent protein catabolism","P",62,0.00153017]
["GO:0030528","transcription regulator activity","F",20,0.00163101]
["GO:0000917","barrier septum formation","P",1,0.00164142]
["GO:0008105","asymmetric protein localization","P",1,0.00164142]
["GO:0005634","nucleus","C",1071,0.00194115]
["GO:0040020","regulation of meiosis","P",12,0.00199868]
["GO:0000154","rRNA modification","P",15,0.00352209]
["GO:0008835","diaminohydroxyphosphoribosylaminopyrimidine deaminase activity","F",1,0.00359703]
["GO:0006270","DNA replication initiation","P",24,0.00383496]
["GO:0005940","septin ring","C",6,0.00455499]
["GO:0000398","nuclear mRNA splicing, via spliceosome","P",72,0.00467812]
["GO:0006273","lagging strand elongation","P",16,0.00531381]
["GO:0004343","glucosamine 6-phosphate N-acetyltransferase activity","F",1,0.00539142]
["GO:0006388","tRNA splicing","P",14,0.00581671]
["GO:0006119","oxidative phosphorylation","P",2,0.00612662]
["GO:0030869","RENT complex","C",4,0.00616819]
["GO:0006281","DNA repair","P",61,0.00623146]
["GO:0000027","ribosomal large subunit assembly and maintenance","P",39,0.00626864]
["GO:0006367","transcription initiation from RNA polymerase II promoter","P",43,0.0068736]
["GO:0008168","methyltransferase activity","F",3,0.00689176]
["GO:0000097","sulfur amino acid biosynthesis","P",2,0.00701437]
["GO:0006384","transcription initiation from RNA polymerase III promoter","P",11,0.00721517]
["GO:0005746","mitochondrial electron transport chain","C",1,0.0074687]
["GO:0045153","electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity","F",1,0.0074687]
["GO:0016586","RSC complex","C",13,0.00797131]
["GO:0016251","general RNA polymerase II transcription factor activity","F",41,0.00798673]
["GO:0000815","ESCRT III complex","C",4,0.00804468]
["GO:0005657","replication fork","C",13,0.00983531]
["GO:0005669","transcription factor TFIID complex","C",15,0.0102491]
["GO:0008156","negative regulation of DNA replication","P",2,0.0117828]
["GO:0004356","glutamate-ammonia ligase activity","F",1,0.0121167]
["GO:0006542","glutamine biosynthesis","P",1,0.0121167]
["GO:0005851","eukaryotic translation initiation factor 2B complex","C",5,0.0123265]
["GO:0000078","cell morphogenesis checkpoint","P",2,0.0125748]
["GO:0030532","small nuclear ribonucleoprotein complex","C",10,0.0127612]
["GO:0005770","late endosome","C",12,0.0128954]
["GO:0000114","G1-specific transcription in mitotic cell cycle","P",14,0.0132077]
["GO:0015674","di-, tri-valent inorganic cation transport","P",2,0.0132389]
["GO:0006744","ubiquinone biosynthesis","P",2,0.0135127]
["GO:0000135","septin checkpoint","P",4,0.0138368]
["GO:0004305","ethanolamine kinase activity","F",1,0.0140521]
["GO:0016568","chromatin modification","P",19,0.0145967]
["GO:0015937","coenzyme A biosynthesis","P",7,0.0146852]
["GO:0003709","RNA polymerase III transcription factor activity","F",10,0.01474]
["GO:0006914","autophagy","P",28,0.0154306]
["GO:0031110","regulation of microtubule polymerization or depolymerization","P",7,0.0154318]
["GO:0006515","misfolded or incompletely synthesized protein catabolism","P",2,0.0157189]
["GO:0042162","telomeric DNA binding","F",9,0.0162276]
["GO:0007127","meiosis I","P",2,0.0171982]
["GO:0016311","dephosphorylation","P",1,0.0172288]
["GO:0003889","alpha DNA polymerase activity","F",4,0.0174969]
["GO:0004450","isocitrate dehydrogenase (NADP+) activity","F",3,0.017641]
["GO:0005677","chromatin silencing complex","C",5,0.0177761]
["GO:0004792","thiosulfate sulfurtransferase activity","F",1,0.017944]
["GO:0019898","extrinsic to membrane","C",20,0.018034]
["GO:0005486","t-SNARE activity","F",10,0.0186951]
["GO:0003838","sterol 24-C-methyltransferase activity","F",1,0.0188646]
["GO:0005658","alpha DNA polymerase:primase complex","C",6,0.0189728]
["GO:0004035","alkaline phosphatase activity","F",2,0.0190155]
["GO:0016576","histone dephosphorylation","P",2,0.0190155]
["GO:0042255","ribosome assembly","P",9,0.0190254]
["GO:0003983","UTP-glucose-1-phosphate uridylyltransferase activity","F",1,0.0193142]
["GO:0006011","UDP-glucose metabolism","P",1,0.0193142]
["GO:0030242","peroxisome degradation","P",3,0.019733]
["GO:0005882","intermediate filament","C",2,0.0199082]
["GO:0000123","histone acetyltransferase complex","C",16,0.0202537]
["GO:0003952","NAD+ synthase (glutamine-hydrolyzing) activity","F",1,0.0204251]
["GO:0001682","tRNA 5'-leader removal","P",1,0.0204538]
["GO:0045046","protein import into peroxisome membrane","P",2,0.0209246]
["GO:0004309","exopolyphosphatase activity","F",1,0.0213054]
["GO:0004004","ATP-dependent RNA helicase activity","F",26,0.0222239]
["GO:0004475","mannose-1-phosphate guanylyltransferase activity","F",1,0.0225477]
["GO:0004407","histone deacetylase activity","F",11,0.0228392]
["GO:0003690","double-stranded DNA binding","F",7,0.0233569]
["GO:0005200","structural constituent of cytoskeleton","F",49,0.0233723]
["GO:0000253","3-keto sterol reductase activity","F",1,0.0234683]
["GO:0030234","enzyme regulator activity","F",17,0.0235676]
["GO:0006303","double-strand break repair via nonhomologous end-joining","P",22,0.0237584]
["GO:0004077","biotin-[acetyl-CoA-carboxylase] ligase activity","F",1,0.0241882]
["GO:0004078","biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity","F",1,0.0241882]
["GO:0004079","biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity","F",1,0.0241882]
["GO:0004080","biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity","F",1,0.0241882]
["GO:0009305","protein amino acid biotinylation","P",1,0.0241882]
["GO:0007096","regulation of exit from mitosis","P",15,0.0242201]
["GO:0003918","DNA topoisomerase (ATP-hydrolyzing) activity","F",1,0.0243353]
["GO:0030123","AP-3 adaptor complex","C",4,0.0260567]
["GO:0000001","mitochondrion inheritance","P",25,0.0262545]
["GO:0008534","purine-specific oxidized base lesion DNA N-glycosylase activity","F",2,0.026387]
["GO:0000126","transcription factor TFIIIB complex","C",3,0.0269893]
["GO:0005686","snRNP U2","C",12,0.0270046]
["GO:0016620","oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor","F",1,0.0272642]
["GO:0004175","endopeptidase activity","F",29,0.028206]
["GO:0000783","nuclear telomere cap complex","C",11,0.0291777]
["GO:0005656","pre-replicative complex","C",15,0.0300655]
["GO:0031385","regulation of termination of mating projection growth","P",5,0.0301203]
["GO:0005637","nuclear inner membrane","C",6,0.0302849]
["GO:0006284","base-excision repair","P",8,0.0303949]
["GO:0006623","protein targeting to vacuole","P",57,0.0305114]
["GO:0042138","meiotic DNA double-strand break formation","P",9,0.030567]
["GO:0042729","DASH complex","C",9,0.0314932]
["GO:0005688","snRNP U6","C",8,0.0319224]
["GO:0000019","regulation of mitotic recombination","P",2,0.0320481]
["GO:0043189","H4/H2A histone acetyltransferase complex","C",12,0.0329788]
["GO:0000731","DNA synthesis during DNA repair","P",4,0.0334407]
["GO:0016573","histone acetylation","P",28,0.0340447]
["GO:0030004","monovalent inorganic cation homeostasis","P",3,0.0341819]
["GO:0006401","RNA catabolism","P",4,0.0343392]
["GO:0042393","histone binding","F",4,0.0350727]
["GO:0006797","polyphosphate metabolism","P",3,0.0352724]
["GO:0000137","Golgi cis cisterna","C",5,0.0365595]
["GO:0015385","sodium:hydrogen antiporter activity","F",1,0.0373182]
["GO:0000727","double-strand break repair via break-induced replication","P",6,0.0373382]
["GO:0015693","magnesium ion transport","P",3,0.0375631]
["GO:0030466","chromatin silencing at silent mating-type cassette","P",22,0.037723]
["GO:0042283","dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity","F",1,0.0377359]
["GO:0006271","DNA strand elongation","P",8,0.037776]
["GO:0004818","glutamate-tRNA ligase activity","F",2,0.0378563]
["GO:0006424","glutamyl-tRNA aminoacylation","P",2,0.0378563]
["GO:0008972","phosphomethylpyrimidine kinase activity","F",3,0.0385292]
["GO:0008180","signalosome complex","C",6,0.0387082]
["GO:0006892","post-Golgi transport","P",3,0.0390712]
["GO:0006261","DNA-dependent DNA replication","P",17,0.0394036]
["GO:0006338","chromatin remodeling","P",51,0.0400404]
["GO:0008535","cytochrome c oxidase complex assembly","P",9,0.0403487]
["GO:0006468","protein amino acid phosphorylation","P",89,0.0405019]
["GO:0007064","mitotic sister chromatid cohesion","P",19,0.0406258]
["GO:0000086","G2/M transition of mitotic cell cycle","P",24,0.0415129]
["GO:0000816","nicotinamide riboside kinase activity","F",1,0.0420942]
["GO:0046495","nicotinamide riboside metabolism","P",1,0.0420942]
["GO:0000161","MAPKKK cascade during osmolarity sensing","P",1,0.0422963]
["GO:0030468","establishment of cell polarity (sensu Fungi)","P",50,0.0424]
["GO:0030337","DNA polymerase processivity factor activity","F",1,0.0424402]
["GO:0003723","RNA binding","F",113,0.0425129]
["GO:0001510","RNA methylation","P",1,0.043078]
["GO:0030870","Mre11 complex","C",3,0.0431025]
["GO:0030684","preribosome","C",1,0.0432422]
["GO:0007020","microtubule nucleation","P",23,0.0433095]
["GO:0031118","rRNA pseudouridine synthesis","P",1,0.0436034]
["GO:0008017","microtubule binding","F",8,0.044092]
["GO:0000770","peptide pheromone export","P",1,0.0442954]
["GO:0004132","dCMP deaminase activity","F",1,0.0445122]
["GO:0006220","pyrimidine nucleotide metabolism","P",1,0.0445122]
["GO:0008409","5'-3' exonuclease activity","F",2,0.0446847]
["GO:0006144","purine base metabolism","P",6,0.0449502]
["GO:0000055","ribosomal large subunit export from nucleus","P",7,0.0453428]
["GO:0006320","Ty1 element transposition","P",1,0.0457884]
["GO:0006322","Ty3 element transposition","P",1,0.0457884]
["GO:0008419","RNA lariat debranching enzyme activity","F",1,0.0457884]
["GO:0000742","karyogamy during conjugation with cellular fusion","P",6,0.0462311]
["GO:0000213","tRNA-intron endonuclease activity","F",4,0.0467219]
["GO:0000214","tRNA-intron endonuclease complex","C",4,0.0467219]
["GO:0006267","pre-replicative complex formation and maintenance","P",13,0.0474259]
["GO:0005515","protein binding","F",176,0.0475729]
["GO:0000119","mediator complex","C",20,0.0479666]
["GO:0006402","mRNA catabolism","P",32,0.0480668]
["GO:0006039","cell wall chitin catabolism","P",1,0.0484559]
["GO:0000754","adaptation to pheromone during conjugation with cellular fusion","P",10,0.0487125]
["GO:0006900","vesicle budding","P",1,0.048942]
["GO:0004595","pantetheine-phosphate adenylyltransferase activity","F",1,0.0493757]
["GO:0004445","inositol-polyphosphate 5-phosphatase activity","F",4,0.0495657]
["GO:0005834","heterotrimeric G-protein complex","C",3,0.0503286]
["GO:0004693","cyclin-dependent protein kinase activity","F",7,0.0515122]
["GO:0042555","MCM complex","C",6,0.051704]
["GO:0017102","methionyl glutamyl tRNA synthetase complex","C",3,0.0517489]
["GO:0006972","hyperosmotic response","P",5,0.0519212]
["GO:0000146","microfilament motor activity","F",6,0.0519491]
["GO:0007118","budding cell apical bud growth","P",11,0.0522161]
["GO:0006298","mismatch repair","P",20,0.0523794]
["GO:0003677","DNA binding","F",86,0.0527934]
["GO:0004637","phosphoribosylamine-glycine ligase activity","F",1,0.0534398]
["GO:0004641","phosphoribosylformylglycinamidine cyclo-ligase activity","F",1,0.0534398]
["GO:0006280","mutagenesis","P",7,0.0537764]
["GO:0005789","endoplasmic reticulum membrane","C",70,0.0538432]
["GO:0004140","dephospho-CoA kinase activity","F",1,0.0539346]
["GO:0008934","inositol-1(or 4)-monophosphatase activity","F",2,0.0541137]
["GO:0046855","inositol phosphate dephosphorylation","P",2,0.0541137]
["GO:0005673","transcription factor TFIIE complex","C",2,0.0541352]
["GO:0006626","protein targeting to mitochondrion","P",5,0.0544152]
["GO:0000010","trans-hexaprenyltranstransferase activity","F",1,0.0547545]
["GO:0006285","base-excision repair, AP site formation","P",3,0.0550805]
["GO:0008649","rRNA methyltransferase activity","F",1,0.055236]
["GO:0016435","rRNA (guanine) methyltransferase activity","F",1,0.055236]
["GO:0000112","nucleotide-excision repair factor 3 complex","C",7,0.0558405]
["GO:0000182","rDNA binding","F",6,0.0562333]
["GO:0016887","ATPase activity","F",63,0.0564233]
["GO:0019773","proteasome core complex, alpha-subunit complex (sensu Eukaryota)","C",7,0.0569177]
["GO:0007131","meiotic recombination","P",29,0.0569931]
["GO:0005885","Arp2/3 protein complex","C",7,0.0571325]
["GO:0005821","intermediate layer of spindle pole body","C",1,0.0573893]
["GO:0006354","RNA elongation","P",1,0.0579549]
["GO:0046975","histone lysine N-methyltransferase activity (H3-K36 specific)","F",1,0.0579549]
["GO:0007097","nuclear migration","P",4,0.0581868]
["GO:0016407","acetyltransferase activity","F",6,0.0589801]
["GO:0006646","phosphatidylethanolamine biosynthesis","P",5,0.0597202]
["GO:0004515","nicotinate-nucleotide adenylyltransferase activity","F",1,0.0607053]
["GO:0004619","phosphoglycerate mutase activity","F",3,0.0609937]
["GO:0004368","glycerol-3-phosphate dehydrogenase activity","F",1,0.0611641]
["GO:0043162","ubiquitin-dependent protein catabolism via the multivesicular body pathway","P",12,0.0613956]
["GO:0009847","spore germination","P",2,0.0617558]
["GO:0009306","protein secretion","P",8,0.0619714]
["GO:0017108","5'-flap endonuclease activity","F",5,0.0620736]
["GO:0006616","SRP-dependent cotranslational protein targeting to membrane, translocation","P",8,0.0625135]
["GO:0000215","tRNA 2'-phosphotransferase activity","F",1,0.0628099]
["GO:0008177","succinate dehydrogenase (ubiquinone) activity","F",5,0.0628704]
["GO:0000276","proton-transporting ATP synthase complex, coupling factor F(o) (sensu Eukaryota)","C",5,0.0632106]
["GO:0009353","oxoglutarate dehydrogenase complex (sensu Eukaryota)","C",3,0.0633423]
["GO:0004360","glutamine-fructose-6-phosphate transaminase (isomerizing) activity","F",1,0.0641916]
["GO:0004463","leukotriene-A4 hydrolase activity","F",1,0.0643494]
["GO:0007119","budding cell isotropic bud growth","P",10,0.0643742]
["GO:0030188","chaperone regulator activity","F",6,0.0647958]
["GO:0003680","AT DNA binding","F",3,0.0651788]
["GO:0008097","5S rRNA binding","F",2,0.0653014]
["GO:0000155","two-component sensor molecule activity","F",1,0.0655361]
["GO:0004673","protein histidine kinase activity","F",1,0.0655361]
["GO:0030127","COPII vesicle coat","C",8,0.0655477]
["GO:0004489","methylenetetrahydrofolate reductase (NADPH) activity","F",2,0.0659187]
["GO:0000338","protein deneddylation","P",5,0.0664494]
["GO:0016558","protein import into peroxisome matrix","P",6,0.066609]
["GO:0031087","deadenylylation-independent decapping","P",2,0.0667836]
["GO:0030467","establishment and/or maintenance of cell polarity (sensu Fungi)","P",2,0.0670784]
["GO:0004851","uroporphyrin-III C-methyltransferase activity","F",1,0.0673084]
["GO:0006780","uroporphyrinogen III biosynthesis","P",1,0.0673084]
["GO:0004647","phosphoserine phosphatase activity","F",1,0.0676743]
["GO:0004663","Rab-protein geranylgeranyltransferase activity","F",2,0.0680527]
["GO:0005968","Rab-protein geranylgeranyltransferase complex","C",2,0.0680527]
["GO:0006102","isocitrate metabolism","P",5,0.0693819]
["GO:0042392","sphingosine-1-phosphate phosphatase activity","F",2,0.0699278]
["GO:0006873","cell ion homeostasis","P",10,0.0702856]
["GO:0005744","mitochondrial inner membrane presequence translocase complex","C",6,0.070399]
["GO:0005771","multivesicular body","C",2,0.0704393]
["GO:0000280","nuclear division","P",3,0.0708035]
["GO:0003922","GMP synthase (glutamine-hydrolyzing) activity","F",1,0.0708666]
["GO:0004487","methylenetetrahydrofolate dehydrogenase (NAD+) activity","F",1,0.0710858]
["GO:0030611","arsenate reductase activity","F",1,0.0711881]
["GO:0042273","ribosomal large subunit biogenesis","P",19,0.0712119]
["GO:0003972","RNA ligase (ATP) activity","F",1,0.0715025]
["GO:0045016","mitochondrial magnesium ion transport","P",2,0.0719904]
["GO:0000116","G2-specific transcription in mitotic cell cycle","P",1,0.0720197]
["GO:0006555","methionine metabolism","P",15,0.0729453]
["GO:0004395","hexaprenyldihydroxybenzoate methyltransferase activity","F",1,0.0739076]
["GO:0043334","2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity","F",1,0.0739326]
["GO:0004807","triose-phosphate isomerase activity","F",1,0.0740692]
["GO:0004591","oxoglutarate dehydrogenase (succinyl-transferring) activity","F",2,0.0743885]
["GO:0000217","DNA secondary structure binding","F",2,0.0749398]
["GO:0000814","ESCRT II complex","C",3,0.0750511]
["GO:0045014","negative regulation of transcription by glucose","P",3,0.0750511]
["GO:0030121","AP-1 adaptor complex","C",5,0.0759489]
["GO:0000333","telomerase catalytic core complex","C",1,0.0759684]
["GO:0003721","telomeric template RNA reverse transcriptase activity","F",1,0.0759684]
["GO:0009074","aromatic amino acid family catabolism","P",1,0.0760681]
["GO:0000030","mannosyltransferase activity","F",16,0.0763237]
["GO:0005823","central plaque of spindle pole body","C",4,0.077145]
["GO:0006369","transcription termination from RNA polymerase II promoter","P",5,0.0772164]
["GO:0005487","nucleocytoplasmic transporter activity","F",1,0.0773292]
["GO:0016653","oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor","F",1,0.0775248]
["GO:0004723","calcium-dependent protein serine/threonine phosphatase activity","F",3,0.0781407]
["GO:0005034","osmosensor activity","F",3,0.0783136]
["GO:0008408","3'-5' exonuclease activity","F",5,0.0786924]
["GO:0007068","negative regulation of transcription, mitotic","P",1,0.0794939]
["GO:0045836","positive regulation of meiosis","P",1,0.0794939]
["GO:0019774","proteasome core complex, beta-subunit complex (sensu Eukaryota)","C",7,0.0798807]
["GO:0006295","nucleotide-excision repair, DNA incision, 3'-to lesion","P",1,0.0799489]
["GO:0008565","protein transporter activity","F",39,0.0801028]
["GO:0006003","fructose 2,6-bisphosphate metabolism","P",2,0.080263]
["GO:0006110","regulation of glycolysis","P",2,0.080263]
["GO:0000083","G1/S-specific transcription in mitotic cell cycle","P",12,0.0805175]
["GO:0000224","peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity","F",1,0.0811498]
["GO:0006517","protein deglycosylation","P",1,0.0811498]
["GO:0046967","cytosol to ER transport","P",1,0.0816745]
["GO:0004682","protein kinase CK2 activity","F",2,0.0821048]
["GO:0000124","SAGA complex","C",18,0.0822273]
["GO:0003894","zeta DNA polymerase activity","F",2,0.0833743]
["GO:0016035","zeta DNA polymerase complex","C",2,0.0833743]
["GO:0004590","orotidine-5'-phosphate decarboxylase activity","F",1,0.0835672]
["GO:0006452","translational frameshifting","P",3,0.0844427]
["GO:0000120","RNA polymerase I transcription factor complex","C",5,0.0851885]
["GO:0042026","protein refolding","P",1,0.0854095]
["GO:0000776","kinetochore","C",17,0.0854592]
["GO:0006450","regulation of translational fidelity","P",6,0.0862109]
["GO:0019887","protein kinase regulator activity","F",2,0.0868001]
["GO:0004484","mRNA guanylyltransferase activity","F",1,0.0873304]
["GO:0003682","chromatin binding","F",18,0.0874624]
["GO:0003906","DNA-(apurinic or apyrimidinic site) lyase activity","F",3,0.0877876]
["GO:0005198","structural molecule activity","F",51,0.0878064]
["GO:0005825","half bridge of spindle pole body","C",4,0.0885627]
["GO:0006366","transcription from RNA polymerase II promoter","P",44,0.0898036]
["GO:0004386","helicase activity","F",13,0.0903279]
["GO:0008283","cell proliferation","P",4,0.090693]
["GO:0007035","vacuolar acidification","P",21,0.0908414]
["GO:0009090","homoserine biosynthesis","P",3,0.0912552]
["GO:0051183","vitamin transporter activity","F",1,0.0920655]
["GO:0000254","C-4 methylsterol oxidase activity","F",1,0.0926341]
["GO:0004392","heme oxygenase (decyclizing) activity","F",1,0.0938873]
["GO:0004601","peroxidase activity","F",1,0.0938873]
["GO:0042167","heme catabolism","P",1,0.0938873]
["GO:0006031","chitin biosynthesis","P",2,0.0940761]
["GO:0003713","transcription coactivator activity","F",12,0.0946162]
["GO:0007189","G-protein signaling, adenylate cyclase activating pathway","P",1,0.0947761]
["GO:0000040","low affinity iron ion transport","P",1,0.0954437]
["GO:0000118","histone deacetylase complex","C",18,0.0959113]
["GO:0006266","DNA ligation","P",1,0.0960871]
["GO:0017150","tRNA dihydrouridine synthase activity","F",4,0.0962594]
["GO:0006627","mitochondrial protein processing","P",5,0.0966465]
["GO:0006614","SRP-dependent cotranslational protein targeting to membrane","P",3,0.0969963]
["GO:0000788","nuclear nucleosome","C",11,0.0975066]
["GO:0003701","RNA polymerase I transcription factor activity","F",10,0.0976919]
["GO:0007001","chromosome organization and biogenesis (sensu Eukaryota)","P",5,0.0985076]
["GO:0005643","nuclear pore","C",48,0.0985709]
["GO:0006743","ubiquinone metabolism","P",7,0.0986553]
["GO:0004799","thymidylate synthase activity","F",1,0.0996389]
["GO:0006231","dTMP biosynthesis","P",1,0.0996389]
["GO:0008383","manganese superoxide dismutase activity","F",1,0.099827]
["GO:0048017","inositol lipid-mediated signaling","P",13,0.101021]
["GO:0017125","deoxycytidyl transferase activity","F",1,0.101119]
["GO:0031384","regulation of initiation of mating projection growth","P",4,0.102548]
["GO:0005876","spindle microtubule","C",11,0.103266]
["GO:0005524","ATP binding","F",16,0.103585]
["GO:0005674","transcription factor TFIIF complex","C",3,0.103893]
["GO:0004871","signal transducer activity","F",23,0.104207]
["GO:0031569","G2/M transition size control checkpoint","P",1,0.10449]
["GO:0046856","phosphoinositide dephosphorylation","P",7,0.105185]
["GO:0008138","protein tyrosine/serine/threonine phosphatase activity","F",1,0.105976]
["GO:0004583","dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity","F",1,0.106285]
["GO:0006333","chromatin assembly or disassembly","P",19,0.106527]
["GO:0015491","cation:cation antiporter activity","F",2,0.107135]
["GO:0004534","5'-3' exoribonuclease activity","F",2,0.10733]
["GO:0015198","oligopeptide transporter activity","F",3,0.107334]
["GO:0019237","centromeric DNA binding","F",6,0.107578]
["GO:0003924","GTPase activity","F",57,0.107776]
["GO:0000278","mitotic cell cycle","P",2,0.107814]
["GO:0005675","transcription factor TFIIH complex","C",9,0.107891]
["GO:0007070","negative regulation of transcription from RNA polymerase II promoter, mitotic","P",9,0.107891]
["GO:0042134","rRNA primary transcript binding","F",5,0.107975]
["GO:0005763","mitochondrial small ribosomal subunit","C",33,0.108461]
["GO:0019674","NAD metabolism","P",3,0.108493]
["GO:0004864","protein phosphatase inhibitor activity","F",3,0.108841]
["GO:0007117","budding cell bud growth","P",20,0.109196]
["GO:0001320","age-dependent response to reactive oxygen species during chronological cell aging","P",2,0.109606]
["GO:0016579","protein deubiquitination","P",17,0.109665]
["GO:0045721","negative regulation of gluconeogenesis","P",9,0.110005]
["GO:0004739","pyruvate dehydrogenase (acetyl-transferring) activity","F",3,0.111451]
["GO:0019220","regulation of phosphate metabolism","P",1,0.111554]
["GO:0004129","cytochrome-c oxidase activity","F",9,0.11169]
["GO:0005751","respiratory chain complex IV (sensu Eukaryota)","C",9,0.11169]
["GO:0045944","positive regulation of transcription from RNA polymerase II promoter","P",43,0.111894]
["GO:0004844","uracil DNA N-glycosylase activity","F",1,0.1123]
["GO:0042645","mitochondrial nucleoid","C",23,0.11308]
["GO:0050613","delta14-sterol reductase activity","F",1,0.113215]
["GO:0030692","Noc4p-Nop14p complex","C",2,0.113974]
["GO:0005672","transcription factor TFIIA complex","C",2,0.114281]
["GO:0016602","CCAAT-binding factor complex","C",4,0.114425]
["GO:0007004","telomerase-dependent telomere maintenance","P",12,0.114563]
["GO:0004244","mitochondrial inner membrane peptidase activity","F",2,0.115072]
["GO:0005816","spindle pole body","C",45,0.115616]
["GO:0000298","endopolyphosphatase activity","F",1,0.116212]
["GO:0006103","2-oxoglutarate metabolism","P",2,0.116364]
["GO:0016455","RNA polymerase II transcription mediator activity","F",20,0.117092]
["GO:0003848","2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity","F",1,0.117519]
["GO:0004150","dihydroneopterin aldolase activity","F",1,0.117519]
["GO:0004156","dihydropteroate synthase activity","F",1,0.117519]
["GO:0004412","homoserine dehydrogenase activity","F",1,0.11789]
["GO:0000127","transcription factor TFIIIC complex","C",6,0.118009]
["GO:0006190","inosine salvage","P",1,0.118425]
["GO:0050483","IMP 5'-nucleotidase activity","F",1,0.118425]
["GO:0030100","regulation of endocytosis","P",3,0.118496]
["GO:0030620","U2 snRNA binding","F",1,0.119495]
["GO:0019948","SUMO activating enzyme activity","F",2,0.119762]
["GO:0048193","Golgi vesicle transport","P",1,0.120097]
["GO:0004638","phosphoribosylaminoimidazole carboxylase activity","F",1,0.120428]
["GO:0008540","proteasome regulatory particle, base subcomplex (sensu Eukaryota)","C",9,0.122092]
["GO:0004187","carboxypeptidase D activity","F",1,0.122263]
["GO:0004633","phosphopantothenoylcysteine decarboxylase activity","F",3,0.122446]
["GO:0015095","magnesium ion transporter activity","F",3,0.122863]
["GO:0004833","tryptophan 2,3-dioxygenase activity","F",1,0.123462]
["GO:0005089","Rho guanyl-nucleotide exchange factor activity","F",4,0.123588]
["GO:0006878","copper ion homeostasis","P",7,0.123884]
["GO:0000084","S phase of mitotic cell cycle","P",5,0.124133]
["GO:0030472","mitotic spindle organization and biogenesis in nucleus","P",21,0.124169]
["GO:0016791","phosphoric monoester hydrolase activity","F",6,0.124271]
["GO:0004729","protoporphyrinogen oxidase activity","F",1,0.124566]
["GO:0046961","hydrogen-transporting ATPase activity, rotational mechanism","F",12,0.124602]
["GO:0004418","hydroxymethylbilane synthase activity","F",1,0.124765]
["GO:0006359","regulation of transcription from RNA polymerase III promoter","P",5,0.125559]
["GO:0008262","importin-alpha export receptor activity","F",2,0.125964]
["GO:0000717","nucleotide-excision repair, DNA duplex unwinding","P",6,0.126226]
["GO:0006348","chromatin silencing at telomere","P",45,0.127028]
["GO:0006390","transcription from mitochondrial promoter","P",3,0.127463]
["GO:0006857","oligopeptide transport","P",2,0.127531]
["GO:0005956","protein kinase CK2 complex","C",4,0.128152]
["GO:0006356","regulation of transcription from RNA polymerase I promoter","P",4,0.128152]
["GO:0042762","regulation of sulfur metabolism","P",1,0.128895]
["GO:0005313","L-glutamate transporter activity","F",1,0.129127]
["GO:0015183","L-aspartate transporter activity","F",1,0.129127]
["GO:0015810","L-aspartate transport","P",1,0.129127]
["GO:0015813","L-glutamate transport","P",1,0.129127]
["GO:0042542","response to hydrogen peroxide","P",3,0.129296]
["GO:0006307","DNA dealkylation","P",3,0.129341]
["GO:0016593","Cdc73/Paf1 complex","C",5,0.12944]
["GO:0004674","protein serine/threonine kinase activity","F",35,0.131191]
["GO:0007008","outer mitochondrial membrane organization and biogenesis","P",1,0.131225]
["GO:0009231","riboflavin biosynthesis","P",6,0.131939]
["GO:0006269","DNA replication, synthesis of RNA primer","P",7,0.132087]
["GO:0008612","hypusine biosynthesis from peptidyl-lysine","P",1,0.132248]
["GO:0016765","transferase activity, transferring alkyl or aryl (other than methyl) groups","F",1,0.132248]
["GO:0004103","choline kinase activity","F",2,0.132375]
["GO:0005749","respiratory chain complex II (sensu Eukaryota)","C",4,0.132639]
["GO:0006121","mitochondrial electron transport, succinate to ubiquinone","P",4,0.132639]
["GO:0003882","CDP-diacylglycerol-serine O-phosphatidyltransferase activity","F",1,0.133114]
["GO:0006659","phosphatidylserine biosynthesis","P",1,0.133114]
["GO:0006487","protein amino acid N-linked glycosylation","P",31,0.133165]
["GO:0005853","eukaryotic translation elongation factor 1 complex","C",3,0.133601]
["GO:0000922","spindle pole","C",5,0.13388]
["GO:0007076","mitotic chromosome condensation","P",9,0.133902]
["GO:0045144","meiotic sister chromatid segregation","P",1,0.135079]
["GO:0018279","protein amino acid N-linked glycosylation via asparagine","P",2,0.135633]
["GO:0000500","RNA polymerase I upstream activating factor complex","C",4,0.135774]
["GO:0000335","negative regulation of DNA transposition","P",8,0.137337]
["GO:0004024","alcohol dehydrogenase activity, zinc-dependent","F",1,0.137507]
["GO:0006033","chitin localization","P",1,0.137787]
["GO:0000921","septin ring assembly","P",5,0.138449]
["GO:0030276","clathrin binding","F",11,0.139971]
["GO:0003779","actin binding","F",6,0.140028]
["GO:0019318","hexose metabolism","P",2,0.140461]
["GO:0017076","purine nucleotide binding","F",4,0.140668]
["GO:0000062","acyl-CoA binding","F",1,0.140673]
["GO:0015909","long-chain fatty acid transport","P",1,0.140673]
["GO:0006314","intron homing","P",1,0.140938]
["GO:0031202","RNA splicing factor activity, transesterification mechanism","F",50,0.141474]
["GO:0017196","N-terminal peptidyl-methionine acetylation","P",3,0.142312]
["GO:0000221","hydrogen-transporting ATPase V1 domain","C",7,0.142372]
["GO:0005875","microtubule associated complex","C",2,0.14278]
["GO:0005955","calcineurin complex","C",4,0.142784]
["GO:0008686","3,4-dihydroxy-2-butanone-4-phosphate synthase activity","F",1,0.144663]
["GO:0016976","NEDD8 conjugating enzyme activity","F",1,0.144907]
["GO:0016906","sterol 3-beta-glucosyltransferase activity","F",1,0.144969]
["GO:0020037","heme binding","F",3,0.145074]
["GO:0000133","polarisome","C",5,0.145211]
["GO:0005519","cytoskeletal regulatory protein binding","F",5,0.145211]
["GO:0030489","processing of 27S pre-rRNA","P",11,0.1458]
["GO:0000144","septin ring (sensu Saccharomyces)","C",9,0.146145]
["GO:0000739","DNA strand annealing activity","F",2,0.146337]
["GO:0007067","mitosis","P",7,0.147481]
["GO:0003951","NAD+ kinase activity","F",1,0.149307]
["GO:0008902","hydroxymethylpyrimidine kinase activity","F",2,0.149451]
["GO:0007019","microtubule depolymerization","P",2,0.149604]
["GO:0004535","poly(A)-specific ribonuclease activity","F",2,0.150107]
["GO:0031251","PAN complex","C",2,0.150107]
["GO:0005083","small GTPase regulator activity","F",3,0.150217]
["GO:0042779","removal of tRNA 3'-trailer sequence","P",1,0.150336]
["GO:0042781","3'-tRNA processing endoribonuclease activity","F",1,0.150336]
["GO:0000110","nucleotide-excision repair factor 1 complex","C",3,0.150365]
["GO:0006564","L-serine biosynthesis","P",2,0.151974]
["GO:0015629","actin cytoskeleton","C",2,0.152697]
["GO:0004828","serine-tRNA ligase activity","F",2,0.152983]
["GO:0006434","seryl-tRNA aminoacylation","P",2,0.152983]
["GO:0005832","chaperonin-containing T-complex","C",11,0.153238]
["GO:0043332","mating projection tip","C",31,0.153377]
["GO:0010038","response to metal ion","P",3,0.153551]
["GO:0000096","sulfur amino acid metabolism","P",6,0.153717]
["GO:0015088","copper uptake transporter activity","F",3,0.154169]
["GO:0046982","protein heterodimerization activity","F",2,0.15481]
["GO:0046027","phospholipid:diacylglycerol acyltransferase activity","F",1,0.154967]
["GO:0001403","invasive growth (sensu Saccharomyces)","P",33,0.155148]
["GO:0003862","3-isopropylmalate dehydrogenase activity","F",1,0.157065]
["GO:0006397","mRNA processing","P",8,0.157403]
["GO:0006613","cotranslational protein targeting to membrane","P",3,0.157682]
["GO:0046695","SLIK (SAGA-like) complex","C",15,0.15785]
["GO:0000067","DNA replication and chromosome cycle","P",3,0.159214]
["GO:0004072","aspartate kinase activity","F",1,0.160028]
["GO:0008509","anion transporter activity","F",1,0.160028]
["GO:0046713","boron transport","P",1,0.160028]
["GO:0046714","boron binding","F",1,0.160028]
["GO:0046715","boron transporter activity","F",1,0.160028]
["GO:0015923","mannosidase activity","F",2,0.161772]
["GO:0046658","anchored to plasma membrane","C",2,0.161772]
["GO:0006784","heme a biosynthesis","P",4,0.161946]
["GO:0005794","Golgi apparatus","C",58,0.162913]
["GO:0016587","ISW1 complex","C",4,0.163454]
["GO:0004781","sulfate adenylyltransferase (ATP) activity","F",1,0.163466]
["GO:0015918","sterol transport","P",6,0.163634]
["GO:0016889",{"$error":"#N/A"},{"$error":"#N/A"},1,0.163892]
["GO:0016070","RNA metabolism","P",6,0.164167]
["GO:0003908","methylated-DNA-[protein]-cysteine S-methyltransferase activity","F",1,0.164341]
["GO:0006843","mitochondrial citrate transport","P",1,0.164468]
["GO:0000780","condensed nuclear chromosome, pericentric region","C",7,0.166263]
["GO:0006378","mRNA polyadenylylation","P",18,0.166322]
["GO:0005871","kinesin complex","C",6,0.166455]
["GO:0019789","SUMO ligase activity","F",3,0.168473]
["GO:0004852","uroporphyrinogen-III synthase activity","F",1,0.168532]
["GO:0004148","dihydrolipoyl dehydrogenase activity","F",1,0.169092]
["GO:0006550","isoleucine catabolism","P",1,0.169092]
["GO:0006574","valine catabolism","P",1,0.169092]
["GO:0019209","kinase activator activity","F",1,0.169102]
["GO:0018195","peptidyl-arginine modification","P",1,0.169692]
["GO:0003712","transcription cofactor activity","F",8,0.169918]
["GO:0004814","arginine-tRNA ligase activity","F",2,0.170149]
["GO:0000798","nuclear cohesin complex","C",6,0.170314]
["GO:0016514","SWI/SNF complex","C",11,0.170539]
["GO:0004001","adenosine kinase activity","F",1,0.170807]
["GO:0005085","guanyl-nucleotide exchange factor activity","F",12,0.170846]
["GO:0004310","farnesyl-diphosphate farnesyltransferase activity","F",1,0.171223]
["GO:0006420","arginyl-tRNA aminoacylation","P",1,0.171515]
["GO:0015976","carbon utilization","P",1,0.171631]
["GO:0008841","dihydrofolate synthase activity","F",1,0.172044]
["GO:0009105","lipoic acid biosynthesis","P",1,0.172216]
["GO:0017140","lipoic acid synthase activity","F",1,0.172216]
["GO:0005654","nucleoplasm","C",22,0.172977]
["GO:0004075","biotin carboxylase activity","F",1,0.173137]
["GO:0005664","nuclear origin of replication recognition complex","C",6,0.17319]
["GO:0007103","spindle pole body duplication in nuclear envelope","P",12,0.173796]
["GO:0004604","phosphoadenylyl-sulfate reductase (thioredoxin) activity","F",1,0.174306]
["GO:0005671","Ada2/Gcn5/Ada3 transcription activator complex","C",5,0.174629]
["GO:0005525","GTP binding","F",10,0.174946]
["GO:0046037","GMP metabolism","P",2,0.175152]
["GO:0003864","3-methyl-2-oxobutanoate hydroxymethyltransferase activity","F",1,0.175412]
["GO:0019897","extrinsic to plasma membrane","C",5,0.175658]
["GO:0006896","Golgi to vacuole transport","P",17,0.176515]
["GO:0000818","MIND complex","C",4,0.17654]
["GO:0015093","ferrous iron transporter activity","F",1,0.177072]
["GO:0006360","transcription from RNA polymerase I promoter","P",23,0.177207]
["GO:0046907","intracellular transport","P",1,0.177478]
["GO:0030897","HOPS complex","C",6,0.177785]
["GO:0000778","condensed nuclear chromosome kinetochore","C",35,0.178008]
["GO:0000339","RNA cap binding","F",2,0.178255]
["GO:0009396","folic acid and derivative biosynthesis","P",4,0.179913]
["GO:0000715","nucleotide-excision repair, DNA damage recognition","P",7,0.181319]
["GO:0019236","response to pheromone","P",3,0.181674]
["GO:0001402","signal transduction during filamentous growth","P",6,0.182628]
["GO:0006172","ADP biosynthesis","P",1,0.182932]
["GO:0008398","sterol 14-demethylase activity","F",1,0.183202]
["GO:0007024","alpha-tubulin folding","P",2,0.184422]
["GO:0043014","alpha-tubulin binding","F",2,0.184422]
["GO:0006620","posttranslational protein targeting to membrane","P",5,0.186556]
["GO:0006783","heme biosynthesis","P",8,0.187021]
["GO:0000184","mRNA catabolism, nonsense-mediated decay","P",9,0.187262]
["GO:0003850","2-deoxyglucose-6-phosphatase activity","F",2,0.187289]
["GO:0046685","response to arsenic","P",6,0.187765]
["GO:0000703","pyrimidine-specific oxidized base lesion DNA N-glycosylase activity","F",2,0.188283]
["GO:0000257","nitrilase activity","F",1,0.188332]
["GO:0007580","extrachromosomal circular DNA accumulation during cell aging","P",1,0.188784]
["GO:0006790","sulfur metabolism","P",7,0.18904]
["GO:0015992","proton transport","P",4,0.189257]
["GO:0005776","autophagic vacuole","C",2,0.189989]
["GO:0005750","respiratory chain complex III (sensu Eukaryota)","C",9,0.190171]
["GO:0046020","negative regulation of transcription from RNA polymerase II promoter by pheromones","P",2,0.190434]
["GO:0006688","glycosphingolipid biosynthesis","P",3,0.192]
["GO:0046488","phosphatidylinositol metabolism","P",1,0.192207]
["GO:0004421","hydroxymethylglutaryl-CoA synthase activity","F",1,0.192483]
["GO:0016564","transcriptional repressor activity","F",11,0.19271]
["GO:0003910","DNA ligase (ATP) activity","F",2,0.1931]
["GO:0004240","mitochondrial processing peptidase activity","F",2,0.194109]
["GO:0017087","mitochondrial processing peptidase complex","C",2,0.194109]
["GO:0006470","protein amino acid dephosphorylation","P",26,0.194328]
["GO:0008810","cellulase activity","F",1,0.194648]
["GO:0030192","Hsp70/Hsc70 protein regulator activity","F",1,0.194933]
["GO:0000811","GINS complex","C",4,0.197015]
["GO:0004430","1-phosphatidylinositol 4-kinase activity","F",3,0.197355]
["GO:0045290","D-arabinose 1-dehydrogenase [NAD(P)+] activity","F",1,0.19783]
["GO:0004226","Gly-X carboxypeptidase activity","F",1,0.198058]
["GO:0006113","fermentation","P",6,0.199584]
["GO:0003873","6-phosphofructo-2-kinase activity","F",3,0.20052]
["GO:0004168","dolichol kinase activity","F",1,0.200533]
["GO:0005365","myo-inositol transporter activity","F",2,0.201307]
["GO:0015798","myo-inositol transport","P",2,0.201307]
["GO:0031207","Sec62/Sec63 complex","C",4,0.201354]
["GO:0005371","tricarboxylate carrier activity","F",2,0.201482]
["GO:0004197","cysteine-type endopeptidase activity","F",3,0.202233]
["GO:0005793","ER-Golgi intermediate compartment","C",2,0.204534]
["GO:0010044","response to aluminum ion","P",1,0.204763]
["GO:0042994","cytoplasmic sequestering of transcription factor","P",1,0.204763]
["GO:0051219","phosphoprotein binding","F",1,0.204763]
["GO:0004048","anthranilate phosphoribosyltransferase activity","F",1,0.205038]
["GO:0003688","DNA replication origin binding","F",7,0.205447]
["GO:0005048","signal sequence binding","F",9,0.205538]
["GO:0030272","5-formyltetrahydrofolate cyclo-ligase activity","F",1,0.20638600000000001]
["GO:0003714","transcription corepressor activity","F",15,0.207316]
["GO:0007090","regulation of S phase of mitotic cell cycle","P",1,0.209215]
["GO:0008330","protein tyrosine/threonine phosphatase activity","F",1,0.209215]
["GO:0003986","acetyl-CoA hydrolase activity","F",1,0.20929]
["GO:0006084","acetyl-CoA metabolism","P",1,0.20929]
["GO:0006874","calcium ion homeostasis","P",6,0.209377]
["GO:0004843","ubiquitin-specific protease activity","F",17,0.209541]
["GO:0006827","high affinity iron ion transport","P",5,0.210604]
["GO:0000075","cell cycle checkpoint","P",4,0.210625]
["GO:0003704","specific RNA polymerase II transcription factor activity","F",42,0.211503]
["GO:0006099","tricarboxylic acid cycle","P",15,0.211828]
["GO:0046540","U4/U6 x U5 tri-snRNP complex","C",28,0.211852]
["GO:0042274","ribosomal small subunit biogenesis","P",4,0.212295]
["GO:0007010","cytoskeleton organization and biogenesis","P",17,0.212914]
["GO:0006772","thiamin metabolism","P",1,0.214158]
["GO:0006807","nitrogen compound metabolism","P",8,0.214255]
["GO:0019354","siroheme biosynthesis","P",2,0.214869]
["GO:0004831","tyrosine-tRNA ligase activity","F",2,0.215509]
["GO:0006437","tyrosyl-tRNA aminoacylation","P",2,0.215509]
["GO:0016462","pyrophosphatase activity","F",2,0.215815]
["GO:0006885","regulation of pH","P",3,0.215973]
["GO:0000810","diacylglycerol pyrophosphate phosphatase activity","F",1,0.21651]
["GO:0003777","microtubule motor activity","F",9,0.216703]
["GO:0004791","thioredoxin-disulfide reductase activity","F",2,0.217526]
["GO:0006086","acetyl-CoA biosynthesis from pyruvate","P",2,0.21952]
["GO:0003962","cystathionine gamma-synthase activity","F",2,0.219567]
["GO:0042256","mature ribosome assembly","P",1,0.219748]
["GO:0004146","dihydrofolate reductase activity","F",1,0.220252]
["GO:0030135","coated vesicle","C",1,0.220316]
["GO:0004581","dolichyl-phosphate beta-glucosyltransferase activity","F",1,0.220325]
["GO:0019888","protein phosphatase regulator activity","F",1,0.221515]
["GO:0004684","calmodulin-dependent protein kinase I activity","F",1,0.221859]
["GO:0006499","N-terminal protein myristoylation","P",4,0.222413]
["GO:0000910","cytokinesis","P",39,0.222508]
["GO:0005786","signal recognition particle (sensu Eukaryota)","C",6,0.223048]
["GO:0006617","SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition","P",6,0.223048]
["GO:0051131","chaperone-mediated protein complex assembly","P",1,0.223797]
["GO:0000225","N-acetylglucosaminylphosphatidylinositol deacetylase activity","F",1,0.224165]
["GO:0000103","sulfate assimilation","P",10,0.224297]
["GO:0006396","RNA processing","P",7,0.225638]
["GO:0008526","phosphatidylinositol transporter activity","F",5,0.226183]
["GO:0015914","phospholipid transport","P",5,0.226183]
["GO:0006073","glucan metabolism","P",1,0.226802]
["GO:0000266","mitochondrial fission","P",3,0.227724]
["GO:0000306",{"$error":"#N/A"},{"$error":"#N/A"},1,0.227816]
["GO:0042787","protein ubiquitination during ubiquitin-dependent protein catabolism","P",2,0.228523]
["GO:0008143","poly(A) binding","F",5,0.229074]
["GO:0004400","histidinol-phosphate transaminase activity","F",1,0.229578]
["GO:0000753","cellular morphogenesis during conjugation with cellular fusion","P",10,0.22967]
["GO:0001671","ATPase stimulator activity","F",3,0.22969]
["GO:0003774","motor activity","F",4,0.229872]
["GO:0009060","aerobic respiration","P",64,0.230179]
["GO:0001310","extrachromosomal rDNA circle accumulation during replicative cell aging","P",1,0.2302]
["GO:0004527","exonuclease activity","F",2,0.230318]
["GO:0004301","epoxide hydrolase activity","F",2,0.230642]
["GO:0009314","response to radiation","P",1,0.23093]
["GO:0000179","rRNA (adenine-N6,N6-)-dimethyltransferase activity","F",1,0.231178]
["GO:0008536","Ran GTPase binding","F",4,0.23147]
["GO:0007346","regulation of progression through mitotic cell cycle","P",4,0.232452]
["GO:0003939","L-iditol 2-dehydrogenase activity","F",1,0.23321]
["GO:0006013","mannose metabolism","P",1,0.23321]
["GO:0004520","endodeoxyribonuclease activity","F",5,0.233377]
["GO:0000347","THO complex","C",3,0.234372]
["GO:0030478","actin cap","C",15,0.234683]
["GO:0005854","nascent polypeptide-associated complex","C",3,0.234847]
["GO:0051083","cotranslational protein folding","P",3,0.234847]
["GO:0009113","purine base biosynthesis","P",5,0.234888]
["GO:0030969","UFP-specific transcription factor mRNA processing during unfolded protein response","P",2,0.234978]
["GO:0004652","polynucleotide adenylyltransferase activity","F",3,0.235643]
["GO:0004691","cAMP-dependent protein kinase activity","F",3,0.235756]
["GO:0005952","cAMP-dependent protein kinase complex","C",3,0.235756]
["GO:0016125","sterol metabolism","P",8,0.236736]
["GO:0017004","cytochrome complex assembly","P",1,0.237478]
["GO:0048255","mRNA stabilization","P",1,0.237478]
["GO:0000014","single-stranded DNA specific endodeoxyribonuclease activity","F",5,0.237557]
["GO:0000501","flocculation (sensu Saccharomyces)","P",8,0.237646]
["GO:0004788","thiamin diphosphokinase activity","F",1,0.23815]
["GO:0009229","thiamin diphosphate biosynthesis","P",1,0.23815]
["GO:0006302","double-strand break repair","P",11,0.238438]
["GO:0008630","DNA damage response, signal transduction resulting in induction of apoptosis","P",1,0.238658]
["GO:0006904","vesicle docking during exocytosis","P",12,0.240034]
["GO:0007624","ultradian rhythm","P",1,0.240655]
["GO:0046513","ceramide biosynthesis","P",3,0.241583]
["GO:0050291","sphingosine N-acyltransferase activity","F",3,0.241583]
["GO:0000262","mitochondrial chromosome","C",2,0.241825]
["GO:0003890","beta DNA polymerase activity","F",1,0.243504]
["GO:0006287","base-excision repair, gap-filling","P",1,0.243504]
["GO:0005489","electron transporter activity","F",3,0.244003]
["GO:0003905","alkylbase DNA N-glycosylase activity","F",2,0.244245]
["GO:0005967","pyruvate dehydrogenase complex (sensu Eukaryota)","C",5,0.24572]
["GO:0005741","mitochondrial outer membrane","C",26,0.24709]
["GO:0006038","cell wall chitin biosynthesis","P",6,0.247095]
["GO:0000113","nucleotide-excision repair factor 4 complex","C",4,0.247163]
["GO:0005310","dicarboxylic acid transporter activity","F",1,0.247504]
["GO:0006835","dicarboxylic acid transport","P",1,0.247504]
["GO:0031307","integral to mitochondrial outer membrane","C",1,0.248079]
["GO:0003980","UDP-glucose:glycoprotein glucosyltransferase activity","F",1,0.248368]
["GO:0006078","beta-1,6 glucan biosynthesis","P",4,0.248397]
["GO:0000196","MAPKKK cascade during cell wall biogenesis","P",4,0.24863]
["GO:0017062","cytochrome bc(1) complex assembly","P",1,0.251004]
["GO:0006383","transcription from RNA polymerase III promoter","P",20,0.251074]
["GO:0016049","cell growth","P",1,0.251826]
["GO:0019509","methionine salvage","P",2,0.252981]
["GO:0007094","mitotic spindle checkpoint","P",21,0.253221]
["GO:0006048","UDP-N-acetylglucosamine biosynthesis","P",2,0.253844]
["GO:0005476","carnitine:acyl carnitine antiporter activity","F",1,0.254154]
["GO:0019722","calcium-mediated signaling","P",7,0.254832]
["GO:0003746","translation elongation factor activity","F",10,0.254849]
["GO:0004525","ribonuclease III activity","F",1,0.255191]
["GO:0006906","vesicle fusion","P",29,0.255241]
["GO:0006265","DNA topological change","P",5,0.255263]
["GO:0000052","citrulline metabolism","P",1,0.256439]
["GO:0000053","argininosuccinate metabolism","P",1,0.256439]
["GO:0004055","argininosuccinate synthase activity","F",1,0.256439]
["GO:0000131","incipient bud site","C",35,0.256548]
["GO:0006272","leading strand elongation","P",14,0.257212]
["GO:0015867","ATP transport","P",2,0.257336]
["GO:0000295","adenine nucleotide transporter activity","F",1,0.257529]
["GO:0004311","farnesyltranstransferase activity","F",1,0.257665]
["GO:0016114","terpenoid biosynthesis","P",1,0.257665]
["GO:0006811","ion transport","P",2,0.25805]
["GO:0008308","voltage-gated ion-selective channel activity","F",2,0.25805]
["GO:0004798","thymidylate kinase activity","F",1,0.258122]
["GO:0006227","dUDP biosynthesis","P",1,0.258122]
["GO:0006233","dTDP biosynthesis","P",1,0.258122]
["GO:0006235","dTTP biosynthesis","P",1,0.258122]
["GO:0009041","uridylate kinase activity","F",1,0.258122]
["GO:0005666","DNA-directed RNA polymerase III complex","C",17,0.258248]
["GO:0004657","proline dehydrogenase activity","F",1,0.261633]
["GO:0045141",{"$error":"#N/A"},{"$error":"#N/A"},1,0.261868]
["GO:0048278","vesicle docking","P",2,0.262268]
["GO:0006486","protein amino acid glycosylation","P",18,0.262319]
["GO:0030163","protein catabolism","P",11,0.263126]
["GO:0008289","lipid binding","F",5,0.263302]
["GO:0030690","Noc1p-Noc2p complex","C",2,0.26556]
["GO:0008784","alanine racemase activity","F",1,0.265581]
["GO:0030170","pyridoxal phosphate binding","F",1,0.265581]
["GO:0006611","protein export from nucleus","P",31,0.265863]
["GO:0045449","regulation of transcription","P",11,0.265911]
["GO:0015039","NADPH-adrenodoxin reductase activity","F",1,0.265981]
["GO:0004017","adenylate kinase activity","F",2,0.266398]
["GO:0017119","Golgi transport complex","C",8,0.26674]
["GO:0000220","hydrogen-transporting ATPase V0 domain","C",6,0.267505]
["GO:0007089","traversing start control point of mitotic cell cycle","P",5,0.267755]
["GO:0007052","mitotic spindle organization and biogenesis","P",1,0.269635]
["GO:0003893","epsilon DNA polymerase activity","F",4,0.269723]
["GO:0008622","epsilon DNA polymerase complex","C",4,0.269723]
["GO:0030915","Smc5-Smc6 complex","C",4,0.269862]
["GO:0000034","adenine deaminase activity","F",1,0.270205]
["GO:0006146","adenine catabolism","P",1,0.270205]
["GO:0000775","chromosome, pericentric region","C",4,0.270294]
["GO:0000015","phosphopyruvate hydratase complex","C",2,0.270439]
["GO:0000373","Group II intron splicing","P",1,0.270525]
["GO:0043224","nuclear SCF ubiquitin ligase complex","C",2,0.270537]
["GO:0004121","cystathionine beta-lyase activity","F",3,0.272169]
["GO:0006268","DNA unwinding during replication","P",12,0.272271]
["GO:0048205","COPI coating of Golgi vesicle","P",1,0.272508]
["GO:0005047","signal recognition particle binding","F",2,0.27253]
["GO:0005785","signal recognition particle receptor complex","C",2,0.27253]
["GO:0012505","endomembrane system","C",1,0.272754]
["GO:0030636","acetate derivative biosynthesis","P",1,0.272754]
["GO:0004406","H3/H4 histone acetyltransferase activity","F",5,0.272759]
["GO:0004149","dihydrolipoyllysine-residue succinyltransferase activity","F",1,0.273093]
["GO:0000938","GARP complex","C",4,0.273262]
["GO:0016299","regulator of G-protein signaling activity","F",1,0.273732]
["GO:0006876","cadmium ion homeostasis","P",1,0.274083]
["GO:0004352","glutamate dehydrogenase activity","F",2,0.274243]
["GO:0006218","uridine catabolism","P",1,0.274752]
["GO:0045437","uridine nucleosidase activity","F",1,0.274752]
["GO:0004105","choline-phosphate cytidylyltransferase activity","F",1,0.274958]
["GO:0006657","CDP-choline pathway","P",1,0.274958]
["GO:0005740","mitochondrial membrane","C",16,0.275659]
["GO:0050261","ribose isomerase activity","F",1,0.27598]
["GO:0004124","cysteine synthase activity","F",2,0.277423]
["GO:0015173","aromatic amino acid transporter activity","F",1,0.277459]
["GO:0015801","aromatic amino acid transport","P",1,0.277459]
["GO:0004866","endopeptidase inhibitor activity","F",3,0.278691]
["GO:0000318","protein-methionine-R-oxide reductase activity","F",1,0.278921]
["GO:0004602","glutathione peroxidase activity","F",5,0.279068]
["GO:0008677","2-dehydropantoate 2-reductase activity","F",1,0.279963]
["GO:0004721","phosphoprotein phosphatase activity","F",6,0.28032]
["GO:0005819","spindle","C",15,0.280392]
["GO:0006897","endocytosis","P",66,0.280641]
["GO:0000785","chromatin","C",2,0.280752]
["GO:0006883","sodium ion homeostasis","P",3,0.281436]
["GO:0008134","transcription factor binding","F",3,0.281601]
["GO:0005784","translocon complex","C",4,0.281807]
["GO:0008495","protoheme IX farnesyltransferase activity","F",1,0.281898]
["GO:0008553","hydrogen-exporting ATPase activity, phosphorylative mechanism","F",2,0.2819]
["GO:0004451","isocitrate lyase activity","F",1,0.282027]
["GO:0009298","GDP-mannose biosynthesis","P",2,0.282213]
["GO:0006414","translational elongation","P",14,0.283118]
["GO:0007232","osmosensory signaling pathway via Sho1 osmosensor","P",1,0.283449]
["GO:0006123","mitochondrial electron transport, cytochrome c to oxygen","P",7,0.283696]
["GO:0004019","adenylosuccinate synthase activity","F",1,0.283824]
["GO:0046086","adenosine biosynthesis","P",1,0.283824]
["GO:0015116","sulfate transporter activity","F",2,0.284388]
["GO:0000156","two-component response regulator activity","F",2,0.285894]
["GO:0043008","ATP-dependent protein binding","F",1,0.286086]
["GO:0017024","myosin I binding","F",1,0.286308]
["GO:0015793","glycerol transport","P",4,0.286645]
["GO:0004746","riboflavin synthase activity","F",1,0.288084]
["GO:0030029","actin filament-based process","P",3,0.288162]
["GO:0008272","sulfate transport","P",3,0.288314]
["GO:0042720","mitochondrial inner membrane peptidase complex","C",3,0.288872]
["GO:0000301","retrograde transport, vesicle recycling within Golgi","P",4,0.289108]
["GO:0030140","trans-Golgi network transport vesicle","C",2,0.289376]
["GO:0003869","4-nitrophenylphosphatase activity","F",1,0.289415]
["GO:0000077","DNA damage checkpoint","P",13,0.289443]
["GO:0004681","casein kinase I activity","F",3,0.290091]
["GO:0000033","alpha-1,3-mannosyltransferase activity","F",5,0.292461]
["GO:0000915","cytokinesis, contractile ring formation","P",1,0.29352]
["GO:0016574","histone ubiquitination","P",3,0.293622]
["GO:0043161","proteasomal ubiquitin-dependent protein catabolism","P",4,0.29399]
["GO:0030001","metal ion transport","P",2,0.295977]
["GO:0005096","GTPase activator activity","F",8,0.296208]
["GO:0006893","Golgi to plasma membrane transport","P",20,0.296214]
["GO:0017157","regulation of exocytosis","P",1,0.296319]
["GO:0009435","NAD biosynthesis","P",7,0.296734]
["GO:0004375","glycine dehydrogenase (decarboxylating) activity","F",4,0.29702]
["GO:0005960","glycine cleavage complex","C",4,0.29702]
["GO:0006546","glycine catabolism","P",4,0.29702]
["GO:0006913","nucleocytoplasmic transport","P",9,0.297622]
["GO:0046421","methylisocitrate lyase activity","F",1,0.297633]
["GO:0045010","actin nucleation","P",3,0.298356]
["GO:0006350","transcription","P",29,0.298877]
["GO:0008190","eukaryotic initiation factor 4E binding","F",1,0.299289]
["GO:0045821","positive regulation of glycolysis","P",3,0.299503]
["GO:0003985","acetyl-CoA C-acetyltransferase activity","F",1,0.300089]
["GO:0000059","protein import into nucleus, docking","P",4,0.300246]
["GO:0000249","C-22 sterol desaturase activity","F",1,0.300375]
["GO:0004872","receptor activity","F",6,0.301316]
["GO:0008374","O-acyltransferase activity","F",3,0.301646]
["GO:0004379","glycylpeptide N-tetradecanoyltransferase activity","F",1,0.302579]
["GO:0018008","N-terminal peptidyl-glycine N-myristoylation","P",1,0.302579]
["GO:0008157","protein phosphatase 1 binding","F",1,0.302879]
["GO:0016925","protein sumoylation","P",7,0.303677]
["GO:0016966","nitric oxide reductase activity","F",1,0.304343]
["GO:0015228","coenzyme A transporter activity","F",1,0.304785]
["GO:0015880","coenzyme A transport","P",1,0.304785]
["GO:0004033","aldo-keto reductase activity","F",5,0.305345]
["GO:0043021","ribonucleoprotein binding","F",3,0.305659]
["GO:0045053","protein retention in Golgi","P",11,0.306654]
["GO:0006418","tRNA aminoacylation for protein translation","P",2,0.306993]
["GO:0018348","protein amino acid geranylgeranylation","P",4,0.307203]
["GO:0006998","nuclear membrane organization and biogenesis","P",7,0.307814]
["GO:0009070","serine family amino acid biosynthesis","P",4,0.308521]
["GO:0000370","U2-type nuclear mRNA branch site recognition","P",3,0.309126]
["GO:0006289","nucleotide-excision repair","P",20,0.309161]
["GO:0004307","ethanolaminephosphotransferase activity","F",1,0.309268]
["GO:0000736","double-strand break repair via single-strand annealing, removal of nonhomologous ends","P",2,0.309401]
["GO:0006296","nucleotide-excision repair, DNA incision, 5'-to lesion","P",2,0.309401]
["GO:0004648","phosphoserine transaminase activity","F",1,0.309917]
["GO:0015124","allantoate transporter activity","F",1,0.310845]
["GO:0015719","allantoate transport","P",1,0.310845]
["GO:0004680","casein kinase activity","F",1,0.311454]
["GO:0005983","starch catabolism","P",1,0.312444]
["GO:0019776","APG8 conjugating enzyme activity","F",1,0.313635]
["GO:0000706","meiotic DNA double-strand break processing","P",3,0.313936]
["GO:0017112","Rab guanyl-nucleotide exchange factor activity","F",2,0.314939]
["GO:0004853","uroporphyrinogen decarboxylase activity","F",1,0.315872]
["GO:0005745","m-AAA complex","C",2,0.31694]
["GO:0045047","protein targeting to ER","P",13,0.317534]
["GO:0008757","S-adenosylmethionine-dependent methyltransferase activity","F",16,0.317636]
["GO:0045021","error-free DNA repair","P",4,0.319213]
["GO:0000360","cis assembly of U2-type pre-catalytic spliceosome","P",1,0.319428]
["GO:0016233","telomere capping","P",3,0.319487]
["GO:0005839","proteasome core complex (sensu Eukaryota)","C",2,0.319562]
["GO:0035101","FACT complex","C",3,0.319764]
["GO:0003824","catalytic activity","F",1,0.319998]
["GO:0004805","trehalose-phosphatase activity","F",3,0.320134]
["GO:0019413","acetate biosynthesis","P",2,0.320405]
["GO:0008541","proteasome regulatory particle, lid subcomplex (sensu Eukaryota)","C",10,0.3205]
["GO:0004811","tRNA isopentenyltransferase activity","F",1,0.320875]
["GO:0030687","nucleolar preribosome, large subunit precursor","C",2,0.321217]
["GO:0006122","mitochondrial electron transport, ubiquinol to cytochrome c","P",8,0.321565]
["GO:0042054","histone methyltransferase activity","F",2,0.321913]
["GO:0000183","chromatin silencing at rDNA","P",14,0.321942]
["GO:0005507","copper ion binding","F",4,0.322444]
["GO:0004785","copper, zinc superoxide dismutase activity","F",1,0.324541]
["GO:0006801","superoxide metabolism","P",1,0.324541]
["GO:0007051","spindle organization and biogenesis","P",1,0.325041]
["GO:0000794","condensed nuclear chromosome","C",9,0.325225]
["GO:0017056","structural constituent of nuclear pore","F",4,0.325266]
["GO:0004550","nucleoside diphosphate kinase activity","F",1,0.32552]
["GO:0006165","nucleoside diphosphate phosphorylation","P",1,0.32552]
["GO:0009142","nucleoside triphosphate biosynthesis","P",1,0.32552]
["GO:0030136","clathrin-coated vesicle","C",13,0.325679]
["GO:0019439","aromatic compound catabolism","P",1,0.326113]
["GO:0030133","transport vesicle","C",3,0.326543]
["GO:0007329","positive regulation of transcription from RNA polymerase II promoter by pheromones","P",3,0.326703]
["GO:0006567","threonine catabolism","P",3,0.326714]
["GO:0004672","protein kinase activity","F",53,0.327814]
["GO:0016571","histone methylation","P",17,0.328191]
["GO:0007033","vacuole organization and biogenesis","P",10,0.328437]
["GO:0006368","RNA elongation from RNA polymerase II promoter","P",20,0.328847]
["GO:0007606","sensory perception of chemical stimulus","P",3,0.329079]
["GO:0016597","amino acid binding","F",3,0.329079]
["GO:0007534","gene conversion at mating-type locus","P",1,0.329641]
["GO:0004070","aspartate carbamoyltransferase activity","F",1,0.329704]
["GO:0006541","glutamine metabolism","P",1,0.329704]
["GO:0006825","copper ion transport","P",3,0.33043]
["GO:0000316","sulfite transport","P",2,0.330894]
["GO:0000289","poly(A) tail shortening","P",7,0.33093]
["GO:0030015","CCR4-NOT core complex","C",7,0.33093]
["GO:0043248","proteasome assembly","P",5,0.331131]
["GO:0005935","bud neck","C",85,0.331201]
["GO:0016156","fumarate reductase (NADH) activity","F",2,0.332171]
["GO:0015082","di-, tri-valent inorganic cation transporter activity","F",6,0.332461]
["GO:0000741","karyogamy","P",2,0.333418]
["GO:0016811","hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","F",2,0.333738]
["GO:0042254","ribosome biogenesis and assembly","P",5,0.333845]
["GO:0000932","cytoplasmic mRNA processing body","C",7,0.334553]
["GO:0004040","amidase activity","F",2,0.335068]
["GO:0004751","ribose-5-phosphate isomerase activity","F",1,0.335946]
["GO:0005881","cytoplasmic microtubule","C",13,0.335957]
["GO:0015157","oligosaccharide transporter activity","F",1,0.336374]
["GO:0015772","oligosaccharide transport","P",1,0.336374]
["GO:0004775","succinate-CoA ligase (ADP-forming) activity","F",2,0.336486]
["GO:0006104","succinyl-CoA metabolism","P",2,0.336486]
["GO:0045002","double-strand break repair via single-strand annealing","P",6,0.33661]
["GO:0004467","long-chain-fatty-acid-CoA ligase activity","F",5,0.336877]
["GO:0008574","plus-end-directed microtubule motor activity","F",1,0.337237]
["GO:0016758","transferase activity, transferring hexosyl groups","F",2,0.337317]
["GO:0030527","structural constituent of chromatin","F",2,0.337803]
["GO:0001558","regulation of cell growth","P",2,0.338374]
["GO:0004768","stearoyl-CoA 9-desaturase activity","F",1,0.341269]
["GO:0006636","fatty acid desaturation","P",1,0.341269]
["GO:0030148","sphingolipid biosynthesis","P",15,0.341277]
["GO:0004108","citrate (Si)-synthase activity","F",3,0.341386]
["GO:0006605","protein targeting","P",6,0.34141]
["GO:0000149","SNARE binding","F",3,0.341806]
["GO:0009982","pseudouridine synthase activity","F",1,0.341982]
["GO:0040031","snRNA modification","P",1,0.341982]
["GO:0007000","nucleolus organization and biogenesis","P",2,0.342188]
["GO:0009303","rRNA transcription","P",2,0.342205]
["GO:0004018","adenylosuccinate lyase activity","F",1,0.342255]
["GO:0000906","6,7-dimethyl-8-ribityllumazine synthase activity","F",1,0.342831]
["GO:0004402","histone acetyltransferase activity","F",15,0.343706]
["GO:0005840","ribosome","C",26,0.344379]
["GO:0004417","hydroxyethylthiazole kinase activity","F",1,0.344425]
["GO:0004789","thiamin-phosphate diphosphorylase activity","F",1,0.344425]
["GO:0046872","metal ion binding","F",4,0.345212]
["GO:0000358","formation of catalytic U2-type spliceosome for second transesterification step","P",2,0.345263]
["GO:0009749","response to glucose stimulus","P",5,0.345377]
["GO:0009636","response to toxin","P",2,0.345539]
["GO:0008863",{"$error":"#N/A"},{"$error":"#N/A"},2,0.347234]
["GO:0042183",{"$error":"#N/A"},{"$error":"#N/A"},2,0.347234]
["GO:0015431","glutathione S-conjugate-exporting ATPase activity","F",1,0.34729]
["GO:0004106","chorismate mutase activity","F",1,0.34735]
["GO:0000107","imidazoleglycerol-phosphate synthase activity","F",1,0.347732]
["GO:0009127","purine nucleoside monophosphate biosynthesis","P",1,0.347732]
["GO:0001522","pseudouridine synthesis","P",3,0.34799]
["GO:0004821","histidine-tRNA ligase activity","F",1,0.348214]
["GO:0006427","histidyl-tRNA aminoacylation","P",1,0.348214]
["GO:0005678","chromatin assembly complex","C",5,0.348259]
["GO:0009228","thiamin biosynthesis","P",14,0.34834]
["GO:0009061","anaerobic respiration","P",3,0.34839]
["GO:0000177","cytoplasmic exosome (RNase complex)","C",10,0.34937]
["GO:0045041","protein import into mitochondrial intermembrane space","P",6,0.349726]
["GO:0042292","URM1 activating enzyme activity","F",1,0.350164]
["GO:0051082","unfolded protein binding","F",55,0.350697]
["GO:0016272","prefoldin complex","C",6,0.35072]
["GO:0006275","regulation of DNA replication","P",5,0.350746]
["GO:0018063","cytochrome c-heme linkage","P",3,0.351114]
["GO:0004536","deoxyribonuclease activity","F",1,0.351903]
["GO:0004306","ethanolamine-phosphate cytidylyltransferase activity","F",1,0.352136]
["GO:0006379","mRNA cleavage","P",15,0.352149]
["GO:0004694","eukaryotic translation initiation factor 2alpha kinase activity","F",1,0.352475]
["GO:0004452","isopentenyl-diphosphate delta-isomerase activity","F",1,0.353056]
["GO:0008131","amine oxidase activity","F",1,0.35306]
["GO:0043138","3' to 5' DNA helicase activity","F",1,0.353179]
["GO:0006606","protein import into nucleus","P",26,0.354904]
["GO:0000817","COMA complex","C",4,0.355451]
["GO:0003899","DNA-directed RNA polymerase activity","F",33,0.355497]
["GO:0009086","methionine biosynthesis","P",5,0.356219]
["GO:0042174","negative regulation of sporulation","P",1,0.356635]
["GO:0007120","axial bud site selection","P",22,0.357101]
["GO:0004474","malate synthase activity","F",2,0.358791]
["GO:0019170","D-lactaldehyde dehydrogenase activity","F",1,0.358828]
["GO:0015078","hydrogen ion transporter activity","F",1,0.360116]
["GO:0004749","ribose phosphate diphosphokinase activity","F",5,0.360295]
["GO:0006166","purine ribonucleoside salvage","P",5,0.360295]
["GO:0000774","adenyl-nucleotide exchange factor activity","F",1,0.361231]
["GO:0000319","sulfite transporter activity","F",1,0.361286]
["GO:0008186","RNA-dependent ATPase activity","F",2,0.361293]
["GO:0006428","isoleucyl-tRNA aminoacylation","P",1,0.362261]
["GO:0006481","C-terminal protein amino acid methylation","P",1,0.362754]
["GO:0030497","fatty acid elongation","P",3,0.363635]
["GO:0005324","long-chain fatty acid transporter activity","F",2,0.364352]
["GO:0000285","1-phosphatidylinositol-3-phosphate 5-kinase activity","F",1,0.364384]
["GO:0006006","glucose metabolism","P",16,0.364504]
["GO:0017061","S-methyl-5-thioadenosine phosphorylase activity","F",1,0.36473]
["GO:0006974","response to DNA damage stimulus","P",15,0.365327]
["GO:0003702","RNA polymerase II transcription factor activity","F",17,0.366092]
["GO:0004076","biotin synthase activity","F",1,0.366111]
["GO:0006417","regulation of protein biosynthesis","P",1,0.368173]
["GO:0005856","cytoskeleton","C",12,0.368716]
["GO:0016726","oxidoreductase activity, acting on CH2 groups, NAD or NADP as acceptor","F",1,0.36937]
["GO:0006461","protein complex assembly","P",35,0.369475]
["GO:0003871","5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity","F",1,0.370663]
["GO:0005743","mitochondrial inner membrane","C",98,0.371073]
["GO:0000045","autophagic vacuole formation","P",1,0.372118]
["GO:0008270","zinc ion binding","F",3,0.373982]
["GO:0030846","transcription termination from Pol II promoter, RNA polymerase(A) coupled","P",10,0.374397]
["GO:0005227","calcium activated cation channel activity","F",1,0.37553]
["GO:0005244","voltage-gated ion channel activity","F",1,0.37553]
["GO:0005272","sodium channel activity","F",1,0.37553]
["GO:0015281","nonselective cation channel activity","F",1,0.37553]
["GO:0004190","aspartic-type endopeptidase activity","F",6,0.375624]
["GO:0008312","7S RNA binding","F",1,0.375862]
["GO:0005462","UDP-N-acetylglucosamine transporter activity","F",1,0.375932]
["GO:0015788","UDP-N-acetylglucosamine transport","P",1,0.375932]
["GO:0000751","cell cycle arrest in response to pheromone","P",8,0.376669]
["GO:0004003","ATP-dependent DNA helicase activity","F",10,0.376744]
["GO:0000175","3'-5'-exoribonuclease activity","F",18,0.376761]
["GO:0006207","'de novo' pyrimidine base biosynthesis","P",12,0.376851]
["GO:0006863","purine transport","P",1,0.376877]
["GO:0015856","cytosine transport","P",1,0.376877]
["GO:0004222","metalloendopeptidase activity","F",15,0.377089]
["GO:0006501","C-terminal protein lipidation","P",4,0.380929]
["GO:0000228","nuclear chromosome","C",21,0.381598]
["GO:0000709","meiotic joint molecule formation","P",2,0.38189]
["GO:0000722","telomerase-independent telomere maintenance","P",10,0.384305]
["GO:0017110","nucleoside-diphosphatase activity","F",1,0.384865]
["GO:0007264","small GTPase mediated signal transduction","P",21,0.385259]
["GO:0006083","acetate metabolism","P",2,0.385501]
["GO:0003870","5-aminolevulinate synthase activity","F",1,0.38667]
["GO:0000795","synaptonemal complex","C",4,0.387445]
["GO:0006566","threonine metabolism","P",5,0.388099]
["GO:0009302","snoRNA transcription","P",1,0.389788]
["GO:0042578","phosphoric ester hydrolase activity","F",1,0.389788]
["GO:0004632","phosphopantothenate-cysteine ligase activity","F",1,0.389891]
["GO:0004840","ubiquitin conjugating enzyme activity","F",14,0.390777]
["GO:0030473","nuclear migration, microtubule-mediated","P",14,0.39115]
["GO:0030122","AP-2 adaptor complex","C",4,0.391355]
["GO:0030008","TRAPP complex","C",10,0.391642]
["GO:0004748","ribonucleoside-diphosphate reductase activity","F",4,0.392782]
["GO:0005971","ribonucleoside-diphosphate reductase complex","C",4,0.392782]
["GO:0004794","threonine ammonia-lyase activity","F",2,0.393198]
["GO:0000151","ubiquitin ligase complex","C",8,0.393787]
["GO:0030433","ER-associated protein catabolism","P",22,0.393862]
["GO:0015077","monovalent inorganic cation transporter activity","F",1,0.394103]
["GO:0004664","prephenate dehydratase activity","F",1,0.394242]
["GO:0019274","phenylalanine biosynthesis, prephenate pathway","P",1,0.394242]
["GO:0030295","protein kinase activator activity","F",4,0.394684]
["GO:0007021","tubulin folding","P",5,0.394865]
["GO:0006675","mannose inositol phosphoceramide metabolism","P",1,0.394922]
["GO:0005874","microtubule","C",2,0.396229]
["GO:0008897","phosphopantetheinyltransferase activity","F",3,0.396388]
["GO:0018065","protein-cofactor linkage","P",3,0.396388]
["GO:0005537","mannose binding","F",3,0.396523]
["GO:0030474","spindle pole body duplication","P",1,0.397141]
["GO:0006312","mitotic recombination","P",3,0.397284]
["GO:0043254","regulation of protein complex assembly","P",3,0.399724]
["GO:0043291","RAVE complex","C",3,0.399724]
["GO:0004314","[acyl-carrier protein] S-malonyltransferase activity","F",2,0.400332]
["GO:0007017","microtubule-based process","P",8,0.400462]
["GO:0004382","guanosine-diphosphatase activity","F",1,0.401248]
["GO:0045134","uridine-diphosphatase activity","F",1,0.401248]
["GO:0006999","nuclear pore organization and biogenesis","P",27,0.402173]
["GO:0007088","regulation of mitosis","P",4,0.402366]
["GO:0006875","metal ion homeostasis","P",1,0.402377]
["GO:0000070","mitotic sister chromatid segregation","P",36,0.402459]
["GO:0003785","actin monomer binding","F",2,0.402532]
["GO:0045955","negative regulation of calcium ion-dependent exocytosis","P",1,0.402762]
["GO:0000147","actin cortical patch assembly","P",15,0.403119]
["GO:0001324","age-dependent response to oxidative stress during chronological cell aging","P",6,0.403327]
["GO:0005946","alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)","C",4,0.40339]
["GO:0005992","trehalose biosynthesis","P",4,0.40339]
["GO:0004514","nicotinate-nucleotide diphosphorylase (carboxylating) activity","F",1,0.403939]
["GO:0015997","ubiquinone biosynthesis monooxygenase activity","F",1,0.404221]
["GO:0006537","glutamate biosynthesis","P",13,0.404476]
["GO:0017183","peptidyl-diphthamide biosynthesis from peptidyl-histidine","P",4,0.404647]
["GO:0016149","translation release factor activity, codon specific","F",1,0.405083]
["GO:0006882","zinc ion homeostasis","P",10,0.405084]
["GO:0008466","glycogenin glucosyltransferase activity","F",2,0.408678]
["GO:0006552","leucine catabolism","P",2,0.408823]
["GO:0000767","cellular morphogenesis during conjugation","P",2,0.409414]
["GO:0005849","mRNA cleavage factor complex","C",9,0.409511]
["GO:0048306","calcium-dependent protein binding","F",1,0.41031]
["GO:0006812","cation transport","P",3,0.410515]
["GO:0030515","snoRNA binding","F",29,0.41134]
["GO:0030125","clathrin vesicle coat","C",4,0.412453]
["GO:0005869","dynactin complex","C",3,0.412559]
["GO:0019843","rRNA binding","F",5,0.412606]
["GO:0016585","chromatin remodeling complex","C",11,0.412613]
["GO:0016078","tRNA catabolism","P",4,0.412624]
["GO:0031499","TRAMP complex","C",4,0.412624]
["GO:0016439","tRNA-pseudouridine synthase activity","F",2,0.413536]
["GO:0016363","nuclear matrix","C",1,0.413724]
["GO:0005088","Ras guanyl-nucleotide exchange factor activity","F",4,0.413983]
["GO:0009071","serine family amino acid catabolism","P",1,0.414173]
["GO:0003755","peptidyl-prolyl cis-trans isomerase activity","F",13,0.414705]
["GO:0008655","pyrimidine salvage","P",4,0.414839]
["GO:0008605","protein kinase CK2 regulator activity","F",2,0.415134]
["GO:0004588","orotate phosphoribosyltransferase activity","F",2,0.41543]
["GO:0004594","pantothenate kinase activity","F",1,0.416246]
["GO:0045022","early endosome to late endosome transport","P",1,0.416769]
["GO:0004020","adenylylsulfate kinase activity","F",1,0.417589]
["GO:0046324","regulation of glucose import","P",1,0.417897]
["GO:0006842","tricarboxylic acid transport","P",1,0.41819]
["GO:0000158","protein phosphatase type 2A activity","F",8,0.418551]
["GO:0007155","cell adhesion","P",3,0.418567]
["GO:0043330","response to exogenous dsRNA","P",7,0.418609]
["GO:0007533","mating type switching","P",2,0.419009]
["GO:0030126","COPI vesicle coat","C",8,0.419512]
["GO:0004044","amidophosphoribosyltransferase activity","F",1,0.422702]
["GO:0000747","conjugation with cellular fusion","P",29,0.423418]
["GO:0016192","vesicle-mediated transport","P",45,0.423664]
["GO:0004354","glutamate dehydrogenase (NADP+) activity","F",1,0.42441]
["GO:0016580","Sin3 complex","C",3,0.425056]
["GO:0000032","cell wall mannoprotein biosynthesis","P",11,0.425585]
["GO:0000719","photoreactive repair","P",1,0.42756]
["GO:0003904","deoxyribodipyrimidine photo-lyase activity","F",1,0.42756]
["GO:0006760","folic acid and derivative metabolism","P",2,0.428004]
["GO:0000813","ESCRT I complex","C",3,0.42897]
["GO:0045045","secretory pathway","P",11,0.428986]
["GO:0045129","NAD-independent histone deacetylase activity","F",6,0.429096]
["GO:0016180","snRNA processing","P",2,0.429986]
["GO:0008184","glycogen phosphorylase activity","F",1,0.430012]
["GO:0005635","nuclear membrane","C",45,0.430912]
["GO:0005483","soluble NSF attachment protein activity","F",1,0.431444]
["GO:0009922","fatty acid elongase activity","F",3,0.43157]
["GO:0019856","pyrimidine base biosynthesis","P",4,0.431855]
["GO:0006189","'de novo' IMP biosynthesis","P",14,0.431917]
["GO:0003941","L-serine ammonia-lyase activity","F",2,0.431946]
["GO:0004651","polynucleotide 5'-phosphatase activity","F",2,0.432312]
["GO:0031422","RecQ helicase-Topo III complex","C",3,0.432589]
["GO:0009266","response to temperature stimulus","P",1,0.433259]
["GO:0004115","cAMP-specific phosphodiesterase activity","F",2,0.433475]
["GO:0007266","Rho protein signal transduction","P",17,0.434244]
["GO:0004671","protein-S-isoprenylcysteine O-methyltransferase activity","F",1,0.435133]
["GO:0000049","tRNA binding","F",4,0.435497]
["GO:0000210","NAD+ diphosphatase activity","F",1,0.435533]
["GO:0006734","NADH metabolism","P",1,0.435533]
["GO:0045103","intermediate filament-based process","P",1,0.43563]
["GO:0007190","adenylate cyclase activation","P",1,0.43596]
["GO:0000227","oxaloacetate carrier activity","F",1,0.435987]
["GO:0008271","sulfate porter activity","F",1,0.435987]
["GO:0015729","oxaloacetate transport","P",1,0.435987]
["GO:0000902","cellular morphogenesis","P",17,0.436585]
["GO:0006488","dolichol-linked oligosaccharide biosynthesis","P",8,0.437121]
["GO:0003989","acetyl-CoA carboxylase activity","F",2,0.437791]
["GO:0015505","uracil permease activity","F",1,0.438544]
["GO:0015857","uracil transport","P",1,0.438544]
["GO:0008441","3'(2'),5'-bisphosphate nucleotidase activity","F",1,0.439655]
["GO:0042538","hyperosmotic salinity response","P",1,0.439655]
["GO:0001308","loss of chromatin silencing during replicative cell aging","P",8,0.439743]
["GO:0006000","fructose metabolism","P",3,0.440202]
["GO:0030437","sporulation (sensu Fungi)","P",59,0.44027]
["GO:0004707","MAP kinase activity","F",5,0.441101]
["GO:0007026","negative regulation of microtubule depolymerization","P",3,0.44111]
["GO:0000028","ribosomal small subunit assembly and maintenance","P",10,0.442023]
["GO:0008237","metallopeptidase activity","F",4,0.442046]
["GO:0019568","arabinose catabolism","P",4,0.442552]
["GO:0042843","D-xylose catabolism","P",4,0.442552]
["GO:0045946","positive regulation of translation","P",1,0.442618]
["GO:0004142","diacylglycerol cholinephosphotransferase activity","F",1,0.442696]
["GO:0019346","transsulfuration","P",1,0.443395]
["GO:0005478","intracellular transporter activity","F",4,0.444059]
["GO:0005850","eukaryotic translation initiation factor 2 complex","C",3,0.445002]
["GO:0008152","metabolism","P",11,0.445506]
["GO:0004634","phosphopyruvate hydratase activity","F",3,0.445699]
["GO:0008113","protein-methionine-S-oxide reductase activity","F",1,0.445716]
["GO:0000064","L-ornithine transporter activity","F",1,0.446107]
["GO:0000066","mitochondrial ornithine transport","P",1,0.446107]
["GO:0046854","phosphoinositide phosphorylation","P",4,0.446808]
["GO:0004579","dolichyl-diphosphooligosaccharide-protein glycotransferase activity","F",9,0.447279]
["GO:0008250","oligosaccharyl transferase complex","C",9,0.447279]
["GO:0003743","translation initiation factor activity","F",28,0.447736]
["GO:0004073","aspartate-semialdehyde dehydrogenase activity","F",1,0.448651]
["GO:0000092","mitotic anaphase B","P",5,0.449046]
["GO:0004186","carboxypeptidase C activity","F",2,0.449158]
["GO:0004067","asparaginase activity","F",2,0.449327]
["GO:0006530","asparagine catabolism","P",2,0.449327]
["GO:0046686","response to cadmium ion","P",4,0.449422]
["GO:0000790","nuclear chromatin","C",18,0.449595]
["GO:0004618","phosphoglycerate kinase activity","F",1,0.450966]
["GO:0004338","glucan 1,3-beta-glucosidase activity","F",8,0.45108]
["GO:0000025","maltose catabolism","P",1,0.451518]
["GO:0015203","polyamine transporter activity","F",3,0.452266]
["GO:0000750","signal transduction during conjugation with cellular fusion","P",22,0.45241]
["GO:0000349","formation of catalytic spliceosome for first transesterification step","P",2,0.453072]
["GO:0000277","[cytochrome c]-lysine N-methyltransferase activity","F",1,0.453562]
["GO:0004529","exodeoxyribonuclease activity","F",1,0.453686]
["GO:0006308","DNA catabolism","P",1,0.453686]
["GO:0004839","ubiquitin activating enzyme activity","F",1,0.453709]
["GO:0006512","ubiquitin cycle","P",1,0.453709]
["GO:0005847","mRNA cleavage and polyadenylation specificity factor complex","C",15,0.454315]
["GO:0005286","basic amino acid permease activity","F",2,0.454702]
["GO:0005780","extrinsic to intraperoxisomal membrane","C",1,0.45487]
["GO:0045033","peroxisome inheritance","P",1,0.45487]
["GO:0000163","protein phosphatase type 1 activity","F",1,0.45561]
["GO:0005761","mitochondrial ribosome","C",4,0.455775]
["GO:0006108","malate metabolism","P",3,0.45641]
["GO:0030060","L-malate dehydrogenase activity","F",3,0.45641]
["GO:0000942","outer kinetochore of condensed nuclear chromosome","C",2,0.457347]
["GO:0031386","protein tag","F",9,0.457642]
["GO:0001401","mitochondrial sorting and assembly machinery complex","C",4,0.457945]
["GO:0015359","amino acid permease activity","F",3,0.458008]
["GO:0016075","rRNA catabolism","P",4,0.458121]
["GO:0016077","snoRNA catabolism","P",4,0.458121]
["GO:0007242","intracellular signaling cascade","P",4,0.458198]
["GO:0007568","aging","P",1,0.458364]
["GO:0006629","lipid metabolism","P",15,0.460439]
["GO:0004178","leucyl aminopeptidase activity","F",1,0.462045]
["GO:0006518","peptide metabolism","P",1,0.462045]
["GO:0030003","cation homeostasis","P",6,0.463287]
["GO:0000108","repairosome","C",4,0.463362]
["GO:0006090","pyruvate metabolism","P",9,0.46361]
["GO:0004425","indole-3-glycerol-phosphate synthase activity","F",1,0.464232]
["GO:0016944","RNA polymerase II transcription elongation factor activity","F",17,0.464257]
["GO:0000148","1,3-beta-glucan synthase complex","C",3,0.464689]
["GO:0016654",{"$error":"#N/A"},{"$error":"#N/A"},1,0.464753]
["GO:0043065",{"$error":"#N/A"},{"$error":"#N/A"},1,0.464753]
["GO:0004131","cytosine deaminase activity","F",1,0.464764]
["GO:0019858","cytosine metabolism","P",1,0.464764]
["GO:0004616","phosphogluconate dehydrogenase (decarboxylating) activity","F",2,0.464883]
["GO:0019777","APG12 conjugating enzyme activity","F",1,0.465051]
["GO:0008290","F-actin capping protein complex","C",2,0.465092]
["GO:0051016","barbed-end actin filament capping","P",2,0.465092]
["GO:0051268","alpha-keto amide reductase activity","F",1,0.465269]
["GO:0051269","alpha-keto ester reductase activity","F",1,0.465269]
["GO:0006469","negative regulation of protein kinase activity","P",1,0.466475]
["GO:0051180","vitamin transport","P",2,0.467375]
["GO:0004827","proline-tRNA ligase activity","F",2,0.467887]
["GO:0003938","IMP dehydrogenase activity","F",4,0.468218]
["GO:0005868","cytoplasmic dynein complex","C",4,0.468895]
["GO:0004713","protein-tyrosine kinase activity","F",1,0.46959]
["GO:0042145","homotypic vacuole fusion, non-autophagic","P",11,0.469836]
["GO:0005685","snRNP U1","C",17,0.470384]
["GO:0000150","recombinase activity","F",3,0.470634]
["GO:0009966","regulation of signal transduction","P",1,0.471008]
["GO:0030174","regulation of DNA replication initiation","P",1,0.47107]
["GO:0015085","calcium ion transporter activity","F",1,0.471473]
["GO:0015369","calcium:hydrogen antiporter activity","F",1,0.471473]
["GO:0005843","cytosolic small ribosomal subunit (sensu Eukaryota)","C",53,0.471517]
["GO:0006343","establishment of chromatin silencing","P",2,0.47201]
["GO:0005852","eukaryotic translation initiation factor 3 complex","C",7,0.472026]
["GO:0008121","ubiquinol-cytochrome-c reductase activity","F",8,0.472084]
["GO:0004347","glucose-6-phosphate isomerase activity","F",1,0.472499]
["GO:0031124","mRNA 3'-end processing","P",4,0.473242]
["GO:0031490",{"$error":"#N/A"},{"$error":"#N/A"},1,0.473622]
["GO:0043085",{"$error":"#N/A"},{"$error":"#N/A"},1,0.473622]
["GO:0051598",{"$error":"#N/A"},{"$error":"#N/A"},1,0.473622]
["GO:0010009","external side of endosome membrane","C",1,0.47396]
["GO:0006081","aldehyde metabolism","P",9,0.475273]
["GO:0015871","choline transport","P",1,0.475841]
["GO:0006120","mitochondrial electron transport, NADH to ubiquinone","P",1,0.476457]
["GO:0016655","oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor","F",1,0.476457]
["GO:0000755","cytogamy","P",4,0.476493]
["GO:0005624","membrane fraction","C",52,0.476924]
["GO:0019207","kinase regulator activity","F",1,0.477178]
["GO:0000903","cellular morphogenesis during vegetative growth","P",7,0.47832]
["GO:0008106","alcohol dehydrogenase (NADP+) activity","F",3,0.47911]
["GO:0004437","inositol or phosphatidylinositol phosphatase activity","F",2,0.47929]
["GO:0000170","sphingosine hydroxylase activity","F",1,0.479803]
["GO:0000799","nuclear condensin complex","C",5,0.479953]
["GO:0004614","phosphoglucomutase activity","F",2,0.480333]
["GO:0006008","glucose 1-phosphate utilization","P",2,0.480333]
["GO:0006010","glucose 6-phosphate utilization","P",2,0.480333]
["GO:0005622","intracellular","C",46,0.481052]
["GO:0007059","chromosome segregation","P",34,0.481073]
["GO:0016480","negative regulation of transcription from RNA polymerase III promoter","P",1,0.481462]
["GO:0008117","sphinganine-1-phosphate aldolase activity","F",1,0.481535]
["GO:0004420","hydroxymethylglutaryl-CoA reductase (NADPH) activity","F",2,0.481578]
["GO:0006476","protein amino acid deacetylation","P",3,0.481582]
["GO:0004819","glutamine-tRNA ligase activity","F",1,0.482642]
["GO:0006425","glutaminyl-tRNA aminoacylation","P",1,0.482642]
["GO:0005100","Rho GTPase activator activity","F",9,0.483119]
["GO:0006813","potassium ion transport","P",1,0.483578]
["GO:0006407","rRNA export from nucleus","P",26,0.48365]
["GO:0004026","alcohol O-acetyltransferase activity","F",2,0.485019]
["GO:0015031","protein transport","P",8,0.485118]
["GO:0005824","outer plaque of spindle pole body","C",6,0.485696]
["GO:0005663","DNA replication factor C complex","C",10,0.486328]
["GO:0019949","SUMO conjugating enzyme activity","F",1,0.486536]
["GO:0006403","RNA localization","P",1,0.486706]
["GO:0016584","nucleosome spacing","P",3,0.487133]
["GO:0045547","dehydrodolichyl diphosphate synthase activity","F",2,0.487723]
["GO:0008418","protein N-terminal asparagine amidohydrolase activity","F",1,0.487839]
["GO:0007030","Golgi organization and biogenesis","P",1,0.487934]
["GO:0019001","guanyl nucleotide binding","F",1,0.487934]
["GO:0045132","meiotic chromosome segregation","P",6,0.488049]
["GO:0004793","threonine aldolase activity","F",1,0.488161]
["GO:0030435","sporulation","P",13,0.488231]
["GO:0005093","Rab GDP-dissociation inhibitor activity","F",1,0.489582]
["GO:0009069",{"$error":"#N/A"},{"$error":"#N/A"},1,0.489785]
["GO:0006696","ergosterol biosynthesis","P",25,0.489819]
["GO:0005979","regulation of glycogen biosynthesis","P",6,0.489929]
["GO:0006301","postreplication repair","P",12,0.490612]
["GO:0005543","phospholipid binding","F",5,0.49064]
["GO:0000245","spliceosome assembly","P",8,0.490854]
["GO:0006096","glycolysis","P",14,0.491227]
["GO:0000176","nuclear exosome (RNase complex)","C",12,0.491813]
["GO:0004032","aldehyde reductase activity","F",4,0.492407]
["GO:0004772","sterol O-acyltransferase activity","F",2,0.492462]
["GO:0030014","CCR4-NOT complex","C",5,0.492982]
["GO:0001302","replicative cell aging","P",25,0.493145]
["GO:0016126","sterol biosynthesis","P",4,0.493612]
["GO:0008360","regulation of cell shape","P",2,0.493975]
["GO:0005758","mitochondrial intermembrane space","C",24,0.493984]
["GO:0006979","response to oxidative stress","P",40,0.494476]
["GO:0007029","ER organization and biogenesis","P",3,0.494629]
["GO:0015168","glycerol transporter activity","F",2,0.49466]
["GO:0004559","alpha-mannosidase activity","F",1,0.495305]
["GO:0009313","oligosaccharide catabolism","P",1,0.495305]
["GO:0015213","uridine transporter activity","F",1,0.495331]
["GO:0015862","uridine transport","P",1,0.495331]
["GO:0017136","NAD-dependent histone deacetylase activity","F",7,0.49605]
["GO:0008859","exoribonuclease II activity","F",1,0.496105]
["GO:0042176","regulation of protein catabolism","P",2,0.497188]
["GO:0005485","v-SNARE activity","F",14,0.498051]
["GO:0004358","glutamate N-acetyltransferase activity","F",1,0.498212]
["GO:0031204","posttranslational protein targeting to membrane, translocation","P",3,0.498748]
["GO:0004586","ornithine decarboxylase activity","F",1,0.498901]
["GO:0009446","putrescine biosynthesis","P",1,0.498901]
["GO:0007015","actin filament organization","P",56,0.499003]
["GO:0046677","response to antibiotic","P",1,0.499864]
["GO:0006990","unfolded protein response, positive regulation of target gene transcription","P",1,0.499885]
["GO:0006066","alcohol metabolism","P",5,0.500059]
["GO:0005665","DNA-directed RNA polymerase II, core complex","C",13,0.501148]
["GO:0015677","copper ion import","P",5,0.501189]
["GO:0003916","DNA topoisomerase activity","F",2,0.501307]
["GO:0046547","trans-aconitate 3-methyltransferase activity","F",1,0.501706]
["GO:0016310","phosphorylation","P",2,0.50193]
["GO:0007092","anaphase-promoting complex activation during mitotic cell cycle","P",2,0.502077]
["GO:0004243","mitochondrial intermediate peptidase activity","F",1,0.503318]
["GO:0015440","peptide-transporting ATPase activity","F",1,0.503467]
["GO:0031314","extrinsic to mitochondrial inner membrane","C",1,0.503584]
["GO:0006624","vacuolar protein processing or maturation","P",3,0.504278]
["GO:0006075","beta-1,3 glucan biosynthesis","P",4,0.50431]
["GO:0000159","protein phosphatase type 2A complex","C",6,0.504947]
["GO:0004326","tetrahydrofolylpolyglutamate synthase activity","F",2,0.504958]
["GO:0007130","synaptonemal complex formation","P",5,0.505488]
["GO:0004221","ubiquitin thiolesterase activity","F",1,0.506129]
["GO:0006864","pyrimidine nucleotide transport","P",1,0.506178]
["GO:0015218","pyrimidine nucleotide transporter activity","F",1,0.506178]
["GO:0000076","DNA replication checkpoint","P",5,0.509022]
["GO:0016806","dipeptidyl-peptidase and tripeptidyl-peptidase activity","F",1,0.509075]
["GO:0006408","snRNA export from nucleus","P",23,0.509557]
["GO:0006607","NLS-bearing substrate import into nucleus","P",23,0.509557]
["GO:0006608","snRNP protein import into nucleus","P",23,0.509557]
["GO:0006610","ribosomal protein import into nucleus","P",23,0.509557]
["GO:0004239","methionyl aminopeptidase activity","F",2,0.509736]
["GO:0009063","amino acid catabolism","P",3,0.510497]
["GO:0031428","box C/D snoRNP complex","C",1,0.511081]
["GO:0006405","RNA export from nucleus","P",5,0.511326]
["GO:0000111","nucleotide-excision repair factor 2 complex","C",2,0.513283]
["GO:0003860","3-hydroxyisobutyryl-CoA hydrolase activity","F",1,0.513316]
["GO:0005933","bud","C",25,0.514013]
["GO:0015978","carbon utilization by utilization of organic compounds","P",1,0.514103]
["GO:0003689","DNA clamp loader activity","F",7,0.514144]
["GO:0004771","sterol esterase activity","F",3,0.514402]
["GO:0016036","cellular response to phosphate starvation","P",3,0.515785]
["GO:0003891","delta DNA polymerase activity","F",3,0.51604]
["GO:0005659","delta DNA polymerase complex","C",3,0.51604]
["GO:0005845","mRNA cap complex","C",3,0.51674]
["GO:0008175","tRNA methyltransferase activity","F",1,0.517698]
["GO:0042719","mitochondrial intermembrane space protein transporter complex","C",4,0.519251]
["GO:0019171","3-hydroxyacyl-[acyl-carrier protein] dehydratase activity","F",1,0.519307]
["GO:0019538","protein metabolism","P",3,0.519418]
["GO:0006164","purine nucleotide biosynthesis","P",13,0.520195]
["GO:0016789","carboxylic ester hydrolase activity","F",2,0.52021]
["GO:0006625","protein targeting to peroxisome","P",12,0.520872]
["GO:0005937","mating projection","C",6,0.520974]
["GO:0000735","removal of nonhomologous ends","P",4,0.521194]
["GO:0006891","intra-Golgi transport","P",21,0.521594]
["GO:0000074","regulation of progression through cell cycle","P",25,0.521715]
["GO:0000350","formation of catalytic spliceosome for second transesterification step","P",3,0.522127]
["GO:0000386","second spliceosomal transesterification activity","F",3,0.522127]
["GO:0000060","protein import into nucleus, translocation","P",1,0.522463]
["GO:0017050","D-erythro-sphingosine kinase activity","F",2,0.522972]
["GO:0004438","phosphatidylinositol-3-phosphatase activity","F",1,0.522976]
["GO:0000321","re-entry into mitotic cell cycle after pheromone arrest","P",3,0.522992]
["GO:0019408","dolichol biosynthesis","P",1,0.524037]
["GO:0016044","membrane organization and biogenesis","P",2,0.524181]
["GO:0008142","oxysterol binding","F",6,0.52466]
["GO:0005996","monosaccharide metabolism","P",1,0.524757]
["GO:0046526","D-xylulose reductase activity","F",1,0.524757]
["GO:0004163","diphosphomevalonate decarboxylase activity","F",1,0.525738]
["GO:0000031","mannosylphosphate transferase activity","F",1,0.526303]
["GO:0006370","mRNA capping","P",3,0.526323]
["GO:0004824","lysine-tRNA ligase activity","F",2,0.526543]
["GO:0006430","lysyl-tRNA aminoacylation","P",2,0.526543]
["GO:0005621","bud scar","C",1,0.526776]
["GO:0000101","sulfur amino acid transport","P",1,0.527507]
["GO:0000102","L-methionine porter activity","F",1,0.527507]
["GO:0016846","carbon-sulfur lyase activity","F",1,0.527679]
["GO:0000730","DNA recombinase assembly","P",3,0.527944]
["GO:0004059","aralkylamine N-acetyltransferase activity","F",1,0.528144]
["GO:0004145","diamine N-acetyltransferase activity","F",1,0.528144]
["GO:0000707","meiotic DNA recombinase assembly","P",5,0.52889]
["GO:0006357","regulation of transcription from RNA polymerase II promoter","P",68,0.529696]
["GO:0030674","protein binding, bridging","F",13,0.530217]
["GO:0006446","regulation of translational initiation","P",5,0.530343]
["GO:0004313","[acyl-carrier protein] S-acetyltransferase activity","F",1,0.530756]
["GO:0004317","3-hydroxypalmitoyl-[acyl-carrier protein] dehydratase activity","F",1,0.530756]
["GO:0004318","enoyl-[acyl-carrier protein] reductase (NADH) activity","F",1,0.530756]
["GO:0009085","lysine biosynthesis","P",1,0.532003]
["GO:0047046","homoisocitrate dehydrogenase activity","F",1,0.532003]
["GO:0043022","ribosome binding","F",1,0.532395]
["GO:0016481","negative regulation of transcription","P",6,0.53254]
["GO:0006353","transcription termination","P",1,0.533711]
["GO:0007046","ribosome biogenesis","P",17,0.53375]
["GO:0008444","CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity","F",1,0.53379]
["GO:0005887","integral to plasma membrane","C",29,0.534224]
["GO:0007121","bipolar bud site selection","P",32,0.534684]
["GO:0004730","pseudouridylate synthase activity","F",6,0.534842]
["GO:0009651","response to salt stress","P",11,0.535089]
["GO:0019563","glycerol catabolism","P",3,0.536271]
["GO:0003861","3-isopropylmalate dehydratase activity","F",1,0.537238]
["GO:0042626","ATPase activity, coupled to transmembrane movement of substances","F",17,0.537252]
["GO:0006118","electron transport","P",6,0.538687]
["GO:0003961","O-acetylhomoserine aminocarboxypropyltransferase activity","F",1,0.538693]
["GO:0006077","beta-1,6 glucan metabolism","P",1,0.538773]
["GO:0006730","one-carbon compound metabolism","P",7,0.538831]
["GO:0004013","adenosylhomocysteinase activity","F",1,0.54011]
["GO:0016259","selenocysteine metabolism","P",1,0.54011]
["GO:0004822","isoleucine-tRNA ligase activity","F",2,0.540765]
["GO:0004650","polygalacturonase activity","F",1,0.541116]
["GO:0045490","pectin catabolism","P",1,0.541116]
["GO:0009049","aspartic-type signal peptidase activity","F",1,0.5412]
["GO:0016531","copper chaperone activity","F",2,0.541312]
["GO:0006895","Golgi to endosome transport","P",12,0.541351]
["GO:0043144","snoRNA processing","P",1,0.541424]
["GO:0000812","SWR1 complex","C",13,0.542418]
["GO:0006167","AMP biosynthesis","P",1,0.542539]
["GO:0006168","adenine salvage","P",1,0.542539]
["GO:0004408","holocytochrome-c synthase activity","F",2,0.543092]
["GO:0050839","cell adhesion molecule binding","F",3,0.543349]
["GO:0000916","cytokinesis, contractile ring contraction","P",1,0.543379]
["GO:0045159","myosin II binding","F",1,0.543379]
["GO:0009269","response to desiccation","P",10,0.54421]
["GO:0004813","alanine-tRNA ligase activity","F",1,0.544505]
["GO:0006419","alanyl-tRNA aminoacylation","P",1,0.544505]
["GO:0030619","U1 snRNA binding","F",1,0.545108]
["GO:0000132","establishment of mitotic spindle orientation","P",9,0.545181]
["GO:0003720","telomerase activity","F",3,0.54618]
["GO:0005697","telomerase holoenzyme complex","C",3,0.54618]
["GO:0008176","tRNA (guanine-N7-)-methyltransferase activity","F",2,0.546557]
["GO:0004428","inositol or phosphatidylinositol kinase activity","F",3,0.546984]
["GO:0000334","3-hydroxyanthranilate 3,4-dioxygenase activity","F",1,0.547058]
["GO:0004170","dUTP diphosphatase activity","F",1,0.54721]
["GO:0009213","pyrimidine deoxyribonucleoside triphosphate catabolism","P",1,0.54721]
["GO:0004612","phosphoenolpyruvate carboxykinase (ATP) activity","F",1,0.547494]
["GO:0000138","Golgi trans cisterna","C",3,0.548455]
["GO:0005769","early endosome","C",3,0.548455]
["GO:0000166","nucleotide binding","F",1,0.548504]
["GO:0004830","tryptophan-tRNA ligase activity","F",2,0.549139]
["GO:0006436","tryptophanyl-tRNA aminoacylation","P",2,0.549139]
["GO:0006829","zinc ion transport","P",4,0.549581]
["GO:0016409","palmitoyltransferase activity","F",1,0.549724]
["GO:0007265","Ras protein signal transduction","P",16,0.55115]
["GO:0007234","osmosensory signaling pathway via two-component system","P",3,0.551238]
["GO:0005097","Rab GTPase activator activity","F",7,0.551818]
["GO:0004028","aldehyde dehydrogenase activity","F",4,0.551904]
["GO:0004424","imidazoleglycerol-phosphate dehydratase activity","F",1,0.552291]
["GO:0005801","Golgi cis-face","C",3,0.553187]
["GO:0016429","tRNA (adenine-N1-)-methyltransferase activity","F",2,0.55324]
["GO:0004470","malic enzyme activity","F",1,0.553275]
["GO:0003841","1-acylglycerol-3-phosphate O-acyltransferase activity","F",1,0.553376]
["GO:0004564","beta-fructofuranosidase activity","F",1,0.553897]
["GO:0005987","sucrose catabolism","P",1,0.553897]
["GO:0016208","AMP binding","F",1,0.554029]
["GO:0006612","protein targeting to membrane","P",6,0.554102]
["GO:0004366","glycerol-3-phosphate O-acyltransferase activity","F",2,0.554419]
["GO:0016530","metallochaperone activity","F",1,0.554523]
["GO:0016308","1-phosphatidylinositol-4-phosphate 5-kinase activity","F",1,0.555492]
["GO:0030482","actin cable","C",5,0.555722]
["GO:0006800","oxygen and reactive oxygen species metabolism","P",3,0.556144]
["GO:0004250","aminopeptidase I activity","F",1,0.556831]
["GO:0015672","monovalent inorganic cation transport","P",2,0.557163]
["GO:0004409","homoaconitate hydratase activity","F",1,0.558006]
["GO:0004528","phosphodiesterase I activity","F",1,0.558847]
["GO:0008311","double-stranded DNA specific 3'-5' exodeoxyribonuclease activity","F",1,0.558847]
["GO:0004385","guanylate kinase activity","F",1,0.559013]
["GO:0000246","delta24(24-1) sterol reductase activity","F",1,0.559899]
["GO:0006432","phenylalanyl-tRNA aminoacylation","P",2,0.560347]
["GO:0009328","phenylalanine-tRNA ligase complex","C",2,0.560347]
["GO:0008898","homocysteine S-methyltransferase activity","F",2,0.560514]
["GO:0019238","cyclohydrolase activity","F",1,0.560934]
["GO:0005829","cytosol","C",145,0.561615]
["GO:0008623","chromatin accessibility complex","C",4,0.561951]
["GO:0000082","G1/S transition of mitotic cell cycle","P",34,0.562423]
["GO:0006109","regulation of carbohydrate metabolism","P",8,0.563935]
["GO:0016575","histone deacetylation","P",10,0.564016]
["GO:0006310","DNA recombination","P",18,0.565141]
["GO:0045003","double-strand break repair via synthesis-dependent strand annealing","P",5,0.565707]
["GO:0004037","allantoicase activity","F",1,0.567093]
["GO:0008234","cysteine-type peptidase activity","F",5,0.567098]
["GO:0003810","protein-glutamine gamma-glutamyltransferase activity","F",1,0.567611]
["GO:0006751","glutathione catabolism","P",1,0.567611]
["GO:0000234","phosphoethanolamine N-methyltransferase activity","F",1,0.567865]
["GO:0003855","3-dehydroquinate dehydratase activity","F",1,0.56862]
["GO:0003856","3-dehydroquinate synthase activity","F",1,0.56862]
["GO:0003866","3-phosphoshikimate 1-carboxyvinyltransferase activity","F",1,0.56862]
["GO:0004764","shikimate 5-dehydrogenase activity","F",1,0.56862]
["GO:0004765","shikimate kinase activity","F",1,0.56862]
["GO:0008179","adenylate cyclase binding","F",1,0.568684]
["GO:0005798","Golgi vesicle","C",8,0.568793]
["GO:0006406","mRNA export from nucleus","P",54,0.569413]
["GO:0016926","protein desumoylation","P",2,0.570362]
["GO:0016929","SUMO-specific protease activity","F",2,0.570362]
["GO:0008652","amino acid biosynthesis","P",3,0.570383]
["GO:0003999","adenine phosphoribosyltransferase activity","F",2,0.571917]
["GO:0004571","mannosyl-oligosaccharide 1,2-alpha-mannosidase activity","F",1,0.571986]
["GO:0004639","phosphoribosylaminoimidazolesuccinocarboxamide synthase activity","F",1,0.572652]
["GO:0042307","positive regulation of protein import into nucleus","P",1,0.572799]
["GO:0015191","L-methionine transporter activity","F",1,0.572911]
["GO:0009013","succinate-semialdehyde dehydrogenase [NAD(P)+] activity","F",1,0.573369]
["GO:0005288","arginine permease activity","F",1,0.573595]
["GO:0005293","lysine permease activity","F",1,0.573595]
["GO:0010043","response to zinc ion","P",2,0.575524]
["GO:0006496","protein amino acid terminal N-glycosylation","P",1,0.575685]
["GO:0031505","cell wall organization and biogenesis (sensu Fungi)","P",1,0.575685]
["GO:0031206","Sec complex-associated translocon complex","C",2,0.575918]
["GO:0006352",{"$error":"#N/A"},{"$error":"#N/A"},1,0.576047]
["GO:0006886","intracellular protein transport","P",18,0.576354]
["GO:0004128","cytochrome-b5 reductase activity","F",2,0.576433]
["GO:0019933","cAMP-mediated signaling","P",4,0.576569]
["GO:0000006","high affinity zinc uptake transporter activity","F",1,0.576642]
["GO:0006830","high-affinity zinc ion transport","P",1,0.576642]
["GO:0009272","cell wall biosynthesis (sensu Fungi)","P",5,0.576906]
["GO:0030491","heteroduplex formation","P",3,0.578328]
["GO:0008174",{"$error":"#N/A"},{"$error":"#N/A"},1,0.578541]
["GO:0016556",{"$error":"#N/A"},{"$error":"#N/A"},1,0.578541]
["GO:0005934","bud tip","C",48,0.579107]
["GO:0003917","DNA topoisomerase type I activity","F",2,0.57961]
["GO:0016740","transferase activity","F",2,0.580124]
["GO:0005095","GTPase inhibitor activity","F",2,0.580127]
["GO:0004413","homoserine kinase activity","F",1,0.580377]
["GO:0006549","isoleucine metabolism","P",1,0.580377]
["GO:0006995","cellular response to nitrogen starvation","P",2,0.580759]
["GO:0004592","pantoate-beta-alanine ligase activity","F",1,0.581349]
["GO:0007124","pseudohyphal growth","P",49,0.581557]
["GO:0006869","lipid transport","P",3,0.581935]
["GO:0015230","FAD transporter activity","F",1,0.582571]
["GO:0015883","FAD transport","P",1,0.582571]
["GO:0004151","dihydroorotase activity","F",1,0.582786]
["GO:0006221","pyrimidine nucleotide biosynthesis","P",1,0.582786]
["GO:0004725","protein tyrosine phosphatase activity","F",10,0.583483]
["GO:0008645","hexose transport","P",12,0.585061]
["GO:0004089","carbonate dehydratase activity","F",1,0.586092]
["GO:0004038","allantoinase activity","F",1,0.586541]
["GO:0009098","leucine biosynthesis","P",5,0.586621]
["GO:0005736","DNA-directed RNA polymerase I complex","C",14,0.587062]
["GO:0015940","pantothenate biosynthesis","P",8,0.587782]
["GO:0005742","mitochondrial outer membrane translocase complex","C",7,0.588107]
["GO:0051014","actin filament severing","P",1,0.588209]
["GO:0000920","cell separation during cytokinesis","P",1,0.588316]
["GO:0000267","cell fraction","C",2,0.588579]
["GO:0008601","protein phosphatase type 2A regulator activity","F",2,0.588579]
["GO:0042147","retrograde transport, endosome to Golgi","P",10,0.588767]
["GO:0046015","regulation of transcription by glucose","P",1,0.588882]
["GO:0005682","snRNP U5","C",14,0.589075]
["GO:0005846","snRNA cap binding complex","C",2,0.589302]
["GO:0043325","phosphatidylinositol-3,4-bisphosphate binding","F",1,0.590153]
["GO:0030378","serine racemase activity","F",1,0.590518]
["GO:0030848","threo-3-hydroxyaspartate ammonia-lyase activity","F",1,0.590518]
["GO:0042219","amino acid derivative catabolism","P",1,0.590518]
["GO:0004596","peptide alpha-N-acetyltransferase activity","F",8,0.590665]
["GO:0008159","positive transcription elongation factor activity","F",1,0.591089]
["GO:0006741","NADP biosynthesis","P",1,0.591293]
["GO:0042736","NADH kinase activity","F",1,0.591293]
["GO:0008023","transcription elongation factor complex","C",19,0.591298]
["GO:0006387","snRNA capping","P",1,0.591607]
["GO:0030686","90S preribosome","C",1,0.592299]
["GO:0004053","arginase activity","F",1,0.592712]
["GO:0019547","arginine catabolism to ornithine","P",1,0.592712]
["GO:0030145","manganese ion binding","F",1,0.592712]
["GO:0008047","enzyme activator activity","F",14,0.59295]
["GO:0015606","spermidine transporter activity","F",2,0.593163]
["GO:0005980","glycogen catabolism","P",3,0.593668]
["GO:0004449","isocitrate dehydrogenase (NAD+) activity","F",2,0.593846]
["GO:0003706","ligand-regulated transcription factor activity","F",1,0.5943]
["GO:0035091","phosphoinositide binding","F",5,0.59481]
["GO:0016279","protein-lysine N-methyltransferase activity","F",3,0.594814]
["GO:0007584","response to nutrient","P",2,0.595123]
["GO:0004755","saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity","F",1,0.595193]
["GO:0015662","ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism","F",4,0.595351]
["GO:0005388","calcium-transporting ATPase activity","F",3,0.595533]
["GO:0007023","post-chaperonin tubulin folding pathway","P",4,0.59624]
["GO:0045039","protein import into mitochondrial inner membrane","P",9,0.596389]
["GO:0031848","protection from non-homologous end joining at telomere","P",1,0.597767]
["GO:0006097","glyoxylate cycle","P",4,0.598099]
["GO:0004521","endoribonuclease activity","F",4,0.598313]
["GO:0000046","autophagic vacuole fusion","P",1,0.598657]
["GO:0030150","protein import into mitochondrial matrix","P",21,0.598988]
["GO:0017120","polyphosphoinositide phosphatase activity","F",1,0.599249]
["GO:0030189","chaperone activator activity","F",2,0.599572]
["GO:0004848","ureidoglycolate hydrolase activity","F",1,0.599701]
["GO:0004642","phosphoribosylformylglycinamidine synthase activity","F",1,0.599829]
["GO:0008094","DNA-dependent ATPase activity","F",7,0.599846]
["GO:0008135","translation factor activity, nucleic acid binding","F",1,0.600243]
["GO:0004029","aldehyde dehydrogenase (NAD) activity","F",1,0.600509]
["GO:0004340","glucokinase activity","F",1,0.601233]
["GO:0000310","xanthine phosphoribosyltransferase activity","F",1,0.601722]
["GO:0004455","ketol-acid reductoisomerase activity","F",1,0.602231]
["GO:0046107","uracil biosynthesis","P",1,0.602524]
["GO:0004888","transmembrane receptor activity","F",5,0.6029]
["GO:0003881","CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity","F",1,0.604252]
["GO:0006661","phosphatidylinositol biosynthesis","P",1,0.604252]
["GO:0007116","regulation of cell budding","P",1,0.604637]
["GO:0015986","ATP synthesis coupled proton transport","P",16,0.604907]
["GO:0030503","regulation of cell redox homeostasis","P",10,0.605069]
["GO:0004834","tryptophan synthase activity","F",1,0.60518]
["GO:0004014","adenosylmethionine decarboxylase activity","F",1,0.605969]
["GO:0000022","mitotic spindle elongation","P",16,0.606338]
["GO:0000274","proton-transporting ATP synthase, stator stalk (sensu Eukaryota)","C",3,0.606569]
["GO:0016616","oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","F",3,0.607404]
["GO:0004731","purine-nucleoside phosphorylase activity","F",1,0.608361]
["GO:0006152","purine nucleoside catabolism","P",1,0.608361]
["GO:0045333","cellular respiration","P",2,0.608711]
["GO:0003887","DNA-directed DNA polymerase activity","F",7,0.609001]
["GO:0015233","pantothenate transporter activity","F",1,0.60961]
["GO:0015887","pantothenate transport","P",1,0.60961]
["GO:0030261","chromosome condensation","P",2,0.609792]
["GO:0031518","CBF3 complex","C",4,0.610152]
["GO:0006796","phosphate metabolism","P",7,0.610436]
["GO:0006660","phosphatidylserine catabolism","P",1,0.610853]
["GO:0030384","phosphoinositide metabolism","P",1,0.610853]
["GO:0006890","retrograde transport, Golgi to ER","P",21,0.610957]
["GO:0004345","glucose-6-phosphate 1-dehydrogenase activity","F",1,0.611003]
["GO:0000054","ribosome export from nucleus","P",8,0.611057]
["GO:0006997","nuclear organization and biogenesis","P",5,0.611124]
["GO:0004370","glycerol kinase activity","F",1,0.611846]
["GO:0031262","Ndc80 complex","C",4,0.61194]
["GO:0001408","guanine nucleotide transport","P",1,0.612454]
["GO:0001409","guanine nucleotide transporter activity","F",1,0.612454]
["GO:0016651","oxidoreductase activity, acting on NADH or NADPH","F",1,0.61269]
["GO:0004134","4-alpha-glucanotransferase activity","F",1,0.612702]
["GO:0004135","amylo-alpha-1,6-glucosidase activity","F",1,0.612702]
["GO:0030246","carbohydrate binding","F",1,0.612784]
["GO:0004735","pyrroline-5-carboxylate reductase activity","F",1,0.612928]
["GO:0008333","endosome to lysosome transport","P",1,0.613087]
["GO:0010133","proline catabolism to glutamate","P",2,0.613111]
["GO:0018456","aryl-alcohol dehydrogenase activity","F",7,0.61316]
["GO:0003867","4-aminobutyrate transaminase activity","F",1,0.613881]
["GO:0006888","ER to Golgi transport","P",74,0.614161]
["GO:0005488","binding","F",1,0.614344]
["GO:0005753","proton-transporting ATP synthase complex (sensu Eukaryota)","C",3,0.614423]
["GO:0006342","chromatin silencing","P",16,0.614459]
["GO:0004862","cAMP-dependent protein kinase inhibitor activity","F",1,0.614469]
["GO:0004849","uridine kinase activity","F",2,0.61511]
["GO:0004109","coproporphyrinogen oxidase activity","F",1,0.615467]
["GO:0006816","calcium ion transport","P",5,0.615918]
["GO:0004364","glutathione transferase activity","F",4,0.615958]
["GO:0003975","UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity","F",1,0.616345]
["GO:0004722","protein serine/threonine phosphatase activity","F",9,0.6171]
["GO:0004092","carnitine O-acetyltransferase activity","F",3,0.617353]
["GO:0009437","carnitine metabolism","P",3,0.617353]
["GO:0015234","thiamin transporter activity","F",1,0.617936]
["GO:0015888","thiamin transport","P",1,0.617936]
["GO:0006474","N-terminal protein amino acid acetylation","P",3,0.618007]
["GO:0007126","meiosis","P",52,0.618038]
["GO:0004339","glucan 1,4-alpha-glucosidase activity","F",1,0.618092]
["GO:0004410","homocitrate synthase activity","F",2,0.619113]
["GO:0015075","ion transporter activity","F",2,0.619118]
["GO:0004084","branched-chain-amino-acid transaminase activity","F",2,0.61929]
["GO:0051382","kinetochore assembly","P",3,0.619624]
["GO:0000009","alpha-1,6-mannosyltransferase activity","F",6,0.62114]
["GO:0006534","cysteine metabolism","P",2,0.62186]
["GO:0007166","cell surface receptor linked signal transduction","P",1,0.621982]
["GO:0005290","L-histidine transporter activity","F",1,0.622515]
["GO:0015817","L-histidine transport","P",1,0.622515]
["GO:0005975","carbohydrate metabolism","P",12,0.62279]
["GO:0004165","dodecenoyl-CoA delta-isomerase activity","F",2,0.623013]
["GO:0006598","polyamine catabolism","P",3,0.623205]
["GO:0003825","alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity","F",3,0.623291]
["GO:0004696","glycogen synthase kinase 3 activity","F",4,0.623903]
["GO:0008597","calcium-dependent protein serine/threonine phosphatase regulator activity","F",1,0.625408]
["GO:0004327","formaldehyde dehydrogenase (glutathione) activity","F",1,0.625819]
["GO:0042326","negative regulation of phosphorylation","P",1,0.625934]
["GO:0006879","iron ion homeostasis","P",27,0.627529]
["GO:0015664","nicotinamide mononucleotide permease activity","F",1,0.628198]
["GO:0015890","nicotinamide mononucleotide transport","P",1,0.628198]
["GO:0003735","structural constituent of ribosome","F",199,0.628565]
["GO:0015239","multidrug transporter activity","F",4,0.628667]
["GO:0004396","hexokinase activity","F",2,0.629569]
["GO:0000243","commitment complex","C",10,0.629571]
["GO:0008195","phosphatidate phosphatase activity","F",2,0.630266]
["GO:0004816","asparagine-tRNA ligase activity","F",2,0.630732]
["GO:0042148","strand invasion","P",1,0.632193]
["GO:0008650","rRNA (uridine-2'-O-)-methyltransferase activity","F",2,0.63247]
["GO:0001100","negative regulation of exit from mitosis","P",3,0.632936]
["GO:0000372","Group I intron splicing","P",5,0.633177]
["GO:0004585","ornithine carbamoyltransferase activity","F",1,0.633426]
["GO:0006591","ornithine metabolism","P",1,0.633426]
["GO:0005509","calcium ion binding","F",4,0.63516]
["GO:0006915","apoptosis","P",2,0.63524]
["GO:0004113","2',3'-cyclic-nucleotide 3'-phosphodiesterase activity","F",1,0.635475]
["GO:0016972","thiol oxidase activity","F",2,0.637166]
["GO:0051085","chaperone cofactor dependent protein folding","P",1,0.6372]
["GO:0004088","carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity","F",2,0.637508]
["GO:0005951","carbamoyl-phosphate synthase complex","C",2,0.637508]
["GO:0015220","choline transporter activity","F",2,0.637673]
["GO:0006769","nicotinamide metabolism","P",1,0.637912]
["GO:0008112","nicotinamide N-methyltransferase activity","F",1,0.637912]
["GO:0000100","S-methylmethionine transporter activity","F",1,0.638487]
["GO:0015806","S-methylmethionine transport","P",1,0.638487]
["GO:0004502","kynurenine 3-monooxygenase activity","F",1,0.638794]
["GO:0008173","RNA methyltransferase activity","F",2,0.638868]
["GO:0000178","exosome (RNase complex)","C",1,0.639128]
["GO:0005375","copper ion transporter activity","F",1,0.639223]
["GO:0005099","Ras GTPase activator activity","F",3,0.639608]
["GO:0005778","peroxisomal membrane","C",15,0.63969]
["GO:0007129","synapsis","P",6,0.640006]
["GO:0008315","meiotic G2/MI transition","P",1,0.640436]
["GO:0030691","Noc2p-Noc3p complex","C",2,0.641365]
["GO:0006901","vesicle coating","P",2,0.641866]
["GO:0004727","prenylated protein tyrosine phosphatase activity","F",1,0.642384]
["GO:0000017","alpha-glucoside transport","P",2,0.642392]
["GO:0005352","alpha-glucoside:hydrogen symporter activity","F",2,0.642392]
["GO:0006376","mRNA splice site selection","P",3,0.642788]
["GO:0006409","tRNA export from nucleus","P",26,0.643061]
["GO:0006855","multidrug transport","P",8,0.64312]
["GO:0004845","uracil phosphoribosyltransferase activity","F",1,0.643252]
["GO:0030134","ER to Golgi transport vesicle","C",1,0.644697]
["GO:0003786","actin lateral binding","F",2,0.645143]
["GO:0045142",{"$error":"#N/A"},{"$error":"#N/A"},1,0.64604]
["GO:0015926","glucosidase activity","F",6,0.646281]
["GO:0004801","transaldolase activity","F",2,0.646943]
["GO:0006740","NADPH regeneration","P",3,0.647517]
["GO:0008538","proteasome activator activity","F",2,0.647605]
["GO:0006735","NADH regeneration","P",2,0.647679]
["GO:0043115","precorrin-2 dehydrogenase activity","F",1,0.647804]
["GO:0045703","ketoreductase activity","F",1,0.647865]
["GO:0005338","nucleotide-sugar transporter activity","F",2,0.648076]
["GO:0015780","nucleotide-sugar transport","P",2,0.648076]
["GO:0004462","lactoylglutathione lyase activity","F",1,0.648829]
["GO:0045040","protein import into mitochondrial outer membrane","P",3,0.649348]
["GO:0005354","galactose transporter activity","F",5,0.649474]
["GO:0006859","extracellular carbohydrate transport","P",1,0.649742]
["GO:0003987","acetate-CoA ligase activity","F",2,0.649888]
["GO:0006085","acetyl-CoA biosynthesis","P",2,0.649888]
["GO:0030904","retromer complex","C",5,0.650233]
["GO:0008793","aromatic-amino-acid transaminase activity","F",2,0.651176]
["GO:0009072","aromatic amino acid family metabolism","P",2,0.651176]
["GO:0030414","protease inhibitor activity","F",1,0.65184]
["GO:0004750","ribulose-phosphate 3-epimerase activity","F",1,0.652673]
["GO:0004630","phospholipase D activity","F",1,0.652768]
["GO:0000105","histidine biosynthesis","P",14,0.655092]
["GO:0008154","actin polymerization and/or depolymerization","P",5,0.655906]
["GO:0006544","glycine metabolism","P",1,0.656147]
["GO:0005337","nucleoside transporter activity","F",1,0.656391]
["GO:0015858","nucleoside transport","P",1,0.656391]
["GO:0016301","kinase activity","F",4,0.6574]
["GO:0006334","nucleosome assembly","P",5,0.657787]
["GO:0006536","glutamate metabolism","P",1,0.658254]
["GO:0007049","cell cycle","P",18,0.658442]
["GO:0050660","FAD binding","F",1,0.658497]
["GO:0019748",{"$error":"#N/A"},{"$error":"#N/A"},1,0.658708]
["GO:0045462",{"$error":"#N/A"},{"$error":"#N/A"},1,0.658708]
["GO:0005625","soluble fraction","C",33,0.659171]
["GO:0045835","negative regulation of meiosis","P",5,0.659284]
["GO:0042721","mitochondrial inner membrane protein insertion complex","C",4,0.659408]
["GO:0007047","cell wall organization and biogenesis","P",107,0.659861]
["GO:0008060","ARF GTPase activator activity","F",4,0.659862]
["GO:0016291","acyl-CoA thioesterase activity","F",1,0.66117]
["GO:0003959","NADPH dehydrogenase activity","F",2,0.661515]
["GO:0045922","negative regulation of fatty acid metabolism","P",1,0.662575]
["GO:0005477","pyruvate carrier activity","F",1,0.662781]
["GO:0006850","mitochondrial pyruvate transport","P",1,0.662781]
["GO:0009117","nucleotide metabolism","P",6,0.662832]
["GO:0006508","proteolysis","P",29,0.662903]
["GO:0009267","cellular response to starvation","P",3,0.663248]
["GO:0016485","protein processing","P",10,0.663437]
["GO:0000781","chromosome, telomeric region","C",4,0.664064]
["GO:0009268","response to pH","P",3,0.665247]
["GO:0004160","dihydroxy-acid dehydratase activity","F",1,0.665552]
["GO:0005353","fructose transporter activity","F",11,0.666102]
["GO:0015578","mannose transporter activity","F",11,0.666102]
["GO:0007114","cell budding","P",5,0.666294]
["GO:0000095","S-adenosylmethionine transporter activity","F",2,0.666412]
["GO:0015805","S-adenosylmethionine transport","P",2,0.666412]
["GO:0000142","contractile ring (sensu Saccharomyces)","C",13,0.666889]
["GO:0005459","UDP-galactose transporter activity","F",1,0.667876]
["GO:0015785","UDP-galactose transport","P",1,0.667876]
["GO:0006491","N-glycan processing","P",4,0.667929]
["GO:0006973","intracellular accumulation of glycerol","P",1,0.670383]
["GO:0003697","single-stranded DNA binding","F",11,0.670748]
["GO:0003997","acyl-CoA oxidase activity","F",1,0.670854]
["GO:0006987","unfolded protein response, activation of signaling protein activity","P",1,0.671056]
["GO:0004042","amino-acid N-acetyltransferase activity","F",4,0.67187]
["GO:0004099","chitin deacetylase activity","F",2,0.671915]
["GO:0005631","chitosan layer of spore wall","C",2,0.671915]
["GO:0004497","monooxygenase activity","F",1,0.671984]
["GO:0005053","peroxisome targeting signal-2 binding","F",1,0.672809]
["GO:0004736","pyruvate carboxylase activity","F",2,0.673272]
["GO:0016565","general transcriptional repressor activity","F",2,0.673558]
["GO:0000309","nicotinamide-nucleotide adenylyltransferase activity","F",1,0.673592]
["GO:0016337","cell-cell adhesion","P",1,0.673647]
["GO:0004555","alpha,alpha-trehalase activity","F",3,0.673669]
["GO:0005993","trehalose catabolism","P",3,0.673669]
["GO:0004322","ferroxidase activity","F",2,0.674325]
["GO:0046933","hydrogen-transporting ATP synthase activity, rotational mechanism","F",11,0.674438]
["GO:0000300","peripheral to membrane of membrane fraction","C",8,0.674979]
["GO:0004708","MAP kinase kinase activity","F",4,0.675013]
["GO:0016566","specific transcriptional repressor activity","F",11,0.675137]
["GO:0000036","acyl carrier activity","F",1,0.67602]
["GO:0006609","mRNA-binding (hnRNP) protein import into nucleus","P",25,0.676229]
["GO:0004519","endonuclease activity","F",6,0.67646]
["GO:0000329","vacuolar membrane (sensu Fungi)","C",61,0.676528]
["GO:0019432","triacylglycerol biosynthesis","P",2,0.676532]
["GO:0019915","sequestering of lipid","P",2,0.676532]
["GO:0008301","DNA bending activity","F",8,0.676701]
["GO:0008486","diphosphoinositol-polyphosphate diphosphatase activity","F",1,0.677002]
["GO:0015959","diadenosine polyphosphate metabolism","P",1,0.677002]
["GO:0006400","tRNA modification","P",20,0.67719]
["GO:0004367","glycerol-3-phosphate dehydrogenase (NAD+) activity","F",2,0.67742]
["GO:0000079","regulation of cyclin dependent protein kinase activity","P",14,0.677564]
["GO:0030287","periplasmic space (sensu Fungi)","C",6,0.677913]
["GO:0005296","L-proline permease activity","F",4,0.679182]
["GO:0030847","transcription termination from Pol II promoter, RNA polymerase(A)-independent","P",8,0.679465]
["GO:0045892","negative regulation of transcription, DNA-dependent","P",1,0.67976]
["GO:0004335",{"$error":"#N/A"},{"$error":"#N/A"},1,0.679802]
["GO:0009249","protein-lipoylation","P",1,0.680001]
["GO:0016874","ligase activity","F",1,0.680001]
["GO:0004460","L-lactate dehydrogenase (cytochrome) activity","F",1,0.680278]
["GO:0004130","cytochrome-c peroxidase activity","F",1,0.680431]
["GO:0016423","tRNA (guanine) methyltransferase activity","F",2,0.681209]
["GO:0015386","potassium:hydrogen antiporter activity","F",1,0.681531]
["GO:0000772","mating pheromone activity","F",4,0.683123]
["GO:0005827","polar microtubule","C",3,0.683572]
["GO:0045298","tubulin","C",3,0.683572]
["GO:0005274","allantoin permease activity","F",1,0.683817]
["GO:0015720","allantoin transport","P",1,0.683817]
["GO:0008193","tRNA guanylyltransferase activity","F",1,0.68393]
["GO:0000145","exocyst","C",8,0.684333]
["GO:0045332","phospholipid translocation","P",3,0.68465]
["GO:0006887","exocytosis","P",24,0.684825]
["GO:0004141","dethiobiotin synthase activity","F",1,0.685841]
["GO:0008450","O-sialoglycoprotein endopeptidase activity","F",1,0.686322]
["GO:0005084","Rab escort protein activity","F",1,0.686663]
["GO:0004362","glutathione-disulfide reductase activity","F",1,0.68744]
["GO:0004631","phosphomevalonate kinase activity","F",1,0.687624]
["GO:0004659","prenyltransferase activity","F",2,0.687733]
["GO:0045471","response to ethanol","P",1,0.688195]
["GO:0016197","endosome transport","P",2,0.688788]
["GO:0004333","fumarate hydratase activity","F",1,0.689271]
["GO:0006106","fumarate metabolism","P",1,0.689271]
["GO:0006413","translational initiation","P",35,0.689289]
["GO:0004582","dolichyl-phosphate beta-D-mannosyltransferase activity","F",1,0.689445]
["GO:0004523","ribonuclease H activity","F",4,0.689708]
["GO:0019478",{"$error":"#N/A"},{"$error":"#N/A"},1,0.689959]
["GO:0003942","N-acetyl-gamma-glutamyl-phosphate reductase activity","F",1,0.690244]
["GO:0003991","acetylglutamate kinase activity","F",1,0.690244]
["GO:0000721","(R,R)-butanediol dehydrogenase activity","F",1,0.690365]
["GO:0019650","butanediol fermentation","P",1,0.690365]
["GO:0016973","poly(A)+ mRNA export from nucleus","P",6,0.690723]
["GO:0004164","diphthine synthase activity","F",1,0.690797]
["GO:0030371","translation repressor activity","F",3,0.691095]
["GO:0006012","galactose metabolism","P",8,0.691578]
["GO:0051087","chaperone binding","F",11,0.693278]
["GO:0005267","potassium channel activity","F",2,0.695073]
["GO:0006986","response to unfolded protein","P",8,0.69535]
["GO:0045026","plasma membrane fusion","P",3,0.696004]
["GO:0030469","maintenance of cell polarity (sensu Fungi)","P",1,0.69645]
["GO:0016274","protein-arginine N-methyltransferase activity","F",3,0.698736]
["GO:0003963","RNA-3'-phosphate cyclase activity","F",1,0.698839]
["GO:0000139","Golgi membrane","C",15,0.699384]
["GO:0003984","acetolactate synthase activity","F",2,0.699391]
["GO:0005948","acetolactate synthase complex","C",2,0.699391]
["GO:0006089","lactate metabolism","P",2,0.699527]
["GO:0046873","metal ion transporter activity","F",1,0.699532]
["GO:0005838","proteasome regulatory particle (sensu Eukaryota)","C",4,0.69954]
["GO:0015275","stretch-activated, cation-selective, calcium channel activity","F",1,0.699736]
["GO:0003876","AMP deaminase activity","F",1,0.700348]
["GO:0006163","purine nucleotide metabolism","P",1,0.700348]
["GO:0003684","damaged DNA binding","F",10,0.700576]
["GO:0004012","phospholipid-translocating ATPase activity","F",6,0.701774]
["GO:0004331","fructose-2,6-bisphosphate 2-phosphatase activity","F",1,0.701962]
["GO:0046403","polynucleotide 3'-phosphatase activity","F",1,0.702311]
["GO:0000162","tryptophan biosynthesis","P",10,0.703192]
["GO:0046688","response to copper ion","P",3,0.703398]
["GO:0048280","vesicle fusion with Golgi apparatus","P",1,0.70351]
["GO:0005844","polysome","C",11,0.703526]
["GO:0008752","FMN reductase activity","F",1,0.704465]
["GO:0000247","C-8 sterol isomerase activity","F",1,0.705229]
["GO:0004066","asparagine synthase (glutamine-hydrolyzing) activity","F",2,0.705325]
["GO:0006529","asparagine biosynthesis","P",2,0.705325]
["GO:0004573","mannosyl-oligosaccharide glucosidase activity","F",1,0.705669]
["GO:0004399","histidinol dehydrogenase activity","F",1,0.707851]
["GO:0004635","phosphoribosyl-AMP cyclohydrolase activity","F",1,0.707851]
["GO:0006950","response to stress","P",66,0.710753]
["GO:0017017","MAP kinase phosphatase activity","F",1,0.711034]
["GO:0016831","carboxy-lyase activity","F",3,0.712057]
["GO:0005779","integral to peroxisomal membrane","C",6,0.712564]
["GO:0004325","ferrochelatase activity","F",2,0.713677]
["GO:0004049","anthranilate synthase activity","F",2,0.713984]
["GO:0005950","anthranilate synthase complex","C",2,0.713984]
["GO:0015204","urea transporter activity","F",1,0.714964]
["GO:0007093","mitotic checkpoint","P",1,0.715808]
["GO:0008889","glycerophosphodiester phosphodiesterase activity","F",1,0.716937]
["GO:0046475","glycerophospholipid catabolism","P",1,0.716937]
["GO:0004754","saccharopine dehydrogenase (NAD+, L-lysine-forming) activity","F",1,0.717004]
["GO:0004371","glycerone kinase activity","F",2,0.717117]
["GO:0006449","regulation of translational termination","P",3,0.717299]
["GO:0005802","Golgi trans face","C",8,0.71744]
["GO:0042989","sequestering of actin monomers","P",1,0.717688]
["GO:0004685","calcium- and calmodulin-dependent protein kinase activity","F",1,0.717835]
["GO:0015226","carnitine transporter activity","F",1,0.718391]
["GO:0015879","carnitine transport","P",1,0.718391]
["GO:0006676","mannosyl diphosphorylinositol ceramide metabolism","P",1,0.718635]
["GO:0008379","thioredoxin peroxidase activity","F",8,0.719213]
["GO:0030259","lipid glycosylation","P",1,0.71944]
["GO:0004817","cysteine-tRNA ligase activity","F",1,0.719483]
["GO:0006423","cysteinyl-tRNA aminoacylation","P",1,0.719483]
["GO:0000802","transverse filament","C",1,0.719617]
["GO:0018987","osmoregulation","P",2,0.719667]
["GO:0009092","homoserine metabolism","P",2,0.720416]
["GO:0008643","carbohydrate transport","P",2,0.720425]
["GO:0015144","carbohydrate transporter activity","F",2,0.720425]
["GO:0015581","maltose porter activity","F",2,0.720425]
["GO:0003937","IMP cyclohydrolase activity","F",2,0.72078]
["GO:0004643","phosphoribosylaminoimidazolecarboxamide formyltransferase activity","F",2,0.72078]
["GO:0004712","protein threonine/tyrosine kinase activity","F",3,0.720785]
["GO:0000307","cyclin-dependent protein kinase holoenzyme complex","C",10,0.720851]
["GO:0000056","ribosomal small subunit export from nucleus","P",1,0.720992]
["GO:0009097","isoleucine biosynthesis","P",1,0.721004]
["GO:0005768","endosome","C",44,0.721489]
["GO:0003988","acetyl-CoA C-acyltransferase activity","F",1,0.722487]
["GO:0045893","positive regulation of transcription, DNA-dependent","P",3,0.722552]
["GO:0015758","glucose transport","P",2,0.722625]
["GO:0030693","caspase activity","F",1,0.723709]
["GO:0005667","transcription factor complex","C",5,0.723769]
["GO:0015631","tubulin binding","F",7,0.723987]
["GO:0004123","cystathionine gamma-lyase activity","F",2,0.724375]
["GO:0004478","methionine adenosyltransferase activity","F",2,0.724401]
["GO:0004365","glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity","F",3,0.724831]
["GO:0015071","protein phosphatase type 2C activity","F",6,0.725989]
["GO:0004176","ATP-dependent peptidase activity","F",2,0.726153]
["GO:0006421","asparaginyl-tRNA aminoacylation","P",1,0.726394]
["GO:0007006","mitochondrial membrane organization and biogenesis","P",2,0.72642]
["GO:0000784","nuclear chromosome, telomeric region","C",9,0.726663]
["GO:0006116","NADH oxidation","P",3,0.72686]
["GO:0008080","N-acetyltransferase activity","F",1,0.727152]
["GO:0005469","succinate:fumarate antiporter activity","F",1,0.727321]
["GO:0015741","fumarate transport","P",1,0.727321]
["GO:0015744","succinate transport","P",1,0.727321]
["GO:0016050","vesicle organization and biogenesis","P",11,0.728919]
["GO:0006464","protein modification","P",10,0.72904]
["GO:0005828","kinetochore microtubule","C",6,0.729201]
["GO:0005364","maltose:hydrogen symporter activity","F",1,0.72961]
["GO:0015574","trehalose transporter activity","F",1,0.72961]
["GO:0015771","trehalose transport","P",1,0.72961]
["GO:0000256","allantoin catabolism","P",6,0.730452]
["GO:0030162","regulation of proteolysis","P",2,0.730499]
["GO:0004458","D-lactate dehydrogenase (cytochrome) activity","F",3,0.731721]
["GO:0004587","ornithine-oxo-acid transaminase activity","F",1,0.73274]
["GO:0006527","arginine catabolism","P",1,0.73274]
["GO:0009051","pentose-phosphate shunt, oxidative branch","P",3,0.73274]
["GO:0004414","homoserine O-acetyltransferase activity","F",1,0.733414]
["GO:0030037","actin filament reorganization during cell cycle","P",4,0.733675]
["GO:0006358","regulation of global transcription from RNA polymerase II promoter","P",2,0.733944]
["GO:0006276","plasmid maintenance","P",6,0.734495]
["GO:0001405","presequence translocase-associated import motor","C",6,0.735375]
["GO:0005554","molecular function unknown","F",1822,0.735662]
["GO:0006559","L-phenylalanine catabolism","P",1,0.7362]
["GO:0050177","phenylpyruvate decarboxylase activity","F",1,0.7362]
["GO:0016578","histone deubiquitination","P",1,0.736252]
["GO:0019840","isoprenoid binding","F",1,0.736272]
["GO:0046470","phosphatidylcholine metabolism","P",2,0.736646]
["GO:0003993","acid phosphatase activity","F",4,0.736925]
["GO:0015248","sterol transporter activity","F",1,0.738213]
["GO:0005797","Golgi medial cisterna","C",1,0.738272]
["GO:0008375","acetylglucosaminyltransferase activity","F",1,0.738272]
["GO:0009082","branched chain family amino acid biosynthesis","P",7,0.738361]
["GO:0030429","kynureninase activity","F",1,0.738551]
["GO:0005471","ATP:ADP antiporter activity","F",3,0.738582]
["GO:0000011","vacuole inheritance","P",15,0.738651]
["GO:0016818","hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides","F",1,0.739373]
["GO:0019781","NEDD8 activating enzyme activity","F",2,0.739905]
["GO:0030036","actin cytoskeleton organization and biogenesis","P",29,0.740041]
["GO:0043137","DNA replication, removal of RNA primer","P",1,0.740564]
["GO:0008599","protein phosphatase type 1 regulator activity","F",8,0.741426]
["GO:0006260","DNA replication","P",21,0.741513]
["GO:0016948","iron hydrogenase activity","F",1,0.741775]
["GO:0016763","transferase activity, transferring pentosyl groups","F",1,0.74185]
["GO:0019988","charged-tRNA modification","P",1,0.74185]
["GO:0007062","sister chromatid cohesion","P",9,0.742445]
["GO:0004045","aminoacyl-tRNA hydrolase activity","F",2,0.742447]
["GO:0019483","beta-alanine biosynthesis","P",2,0.742506]
["GO:0004096","catalase activity","F",2,0.745281]
["GO:0042723","thiamin and derivative metabolism","P",1,0.745748]
["GO:0042493","response to drug","P",18,0.746388]
["GO:0005835","fatty acid synthase complex","C",2,0.74682]
["GO:0043037","translation","P",2,0.747179]
["GO:0006521","regulation of amino acid metabolism","P",1,0.748802]
["GO:0006525","arginine metabolism","P",3,0.749114]
["GO:0000391","U2-type spliceosome disassembly","P",2,0.7495]
["GO:0004039","allophanate hydrolase activity","F",1,0.751968]
["GO:0004847","urea carboxylase activity","F",1,0.751968]
["GO:0019627","urea metabolism","P",1,0.751968]
["GO:0003885","D-arabinono-1,4-lactone oxidase activity","F",1,0.752301]
["GO:0000290","deadenylylation-dependent decapping","P",7,0.75245]
["GO:0004832","valine-tRNA ligase activity","F",1,0.752705]
["GO:0006438","valyl-tRNA aminoacylation","P",1,0.752705]
["GO:0000297","spermine transporter activity","F",4,0.752804]
["GO:0006824","cobalt ion transport","P",2,0.753076]
["GO:0019368","fatty acid elongation, unsaturated fatty acid","P",1,0.753352]
["GO:0016072","rRNA metabolism","P",3,0.754441]
["GO:0016559","peroxisome fission","P",1,0.755594]
["GO:0004809","tRNA (guanine-N2-)-methyltransferase activity","F",3,0.755804]
["GO:0005775","vacuolar lumen","C",1,0.756668]
["GO:0030397","membrane disassembly","P",1,0.756668]
["GO:0030623","U5 snRNA binding","F",2,0.757345]
["GO:0004617","phosphoglycerate dehydrogenase activity","F",2,0.757885]
["GO:0007243","protein kinase cascade","P",3,0.758646]
["GO:0001400","mating projection base","C",4,0.758936]
["GO:0006833","water transport","P",3,0.759204]
["GO:0015250","water channel activity","F",3,0.759204]
["GO:0004349","glutamate 5-kinase activity","F",1,0.759724]
["GO:0006101","citrate metabolism","P",4,0.759734]
["GO:0004742","dihydrolipoyllysine-residue acetyltransferase activity","F",1,0.760914]
["GO:0006747","FAD biosynthesis","P",1,0.761091]
["GO:0006980","redox signal response","P",1,0.762112]
["GO:0004069","aspartate transaminase activity","F",2,0.763369]
["GO:0006532","aspartate biosynthesis","P",2,0.763369]
["GO:0006533","aspartate catabolism","P",2,0.763369]
["GO:0019266","asparagine biosynthesis from oxaloacetate","P",2,0.763369]
["GO:0005262","calcium channel activity","F",3,0.763734]
["GO:0006415","translational termination","P",3,0.764049]
["GO:0017022","myosin binding","F",1,0.765136]
["GO:0016631","enoyl-[acyl-carrier protein] reductase activity","F",1,0.765907]
["GO:0006448","regulation of translational elongation","P",3,0.766001]
["GO:0019655","ethanol fermentation","P",5,0.766201]
["GO:0000140","acylglycerone-phosphate reductase activity","F",1,0.76635]
["GO:0006654","phosphatidic acid biosynthesis","P",1,0.76635]
["GO:0003857","3-hydroxyacyl-CoA dehydrogenase activity","F",1,0.766768]
["GO:0004300","enoyl-CoA hydratase activity","F",1,0.766768]
["GO:0005662","DNA replication factor A complex","C",3,0.766992]
["GO:0006650","glycerophospholipid metabolism","P",2,0.769157]
["GO:0008028","monocarboxylic acid transporter activity","F",6,0.769474]
["GO:0004842","ubiquitin-protein ligase activity","F",35,0.769633]
["GO:0016722","oxidoreductase activity, oxidizing metal ions","F",2,0.769942]
["GO:0004620","phospholipase activity","F",2,0.769981]
["GO:0018444","translation release factor complex","C",2,0.770207]
["GO:0000244","assembly of spliceosomal tri-snRNP","P",2,0.771133]
["GO:0000725","recombinational repair","P",1,0.772206]
["GO:0004401","histidinol-phosphatase activity","F",1,0.772326]
["GO:0000346","transcription export complex","C",3,0.77255]
["GO:0000299","integral to membrane of membrane fraction","C",3,0.77279]
["GO:0006067","ethanol metabolism","P",4,0.773174]
["GO:0008054","cyclin catabolism","P",12,0.773292]
["GO:0015344","siderophore-iron (ferrioxamine) uptake transporter activity","F",1,0.773332]
["GO:0004615","phosphomannomutase activity","F",1,0.773565]
["GO:0016424","tRNA (guanosine) methyltransferase activity","F",1,0.773655]
["GO:0045861","negative regulation of proteolysis","P",2,0.77384]
["GO:0003872","6-phosphofructokinase activity","F",2,0.774397]
["GO:0005945","6-phosphofructokinase complex","C",2,0.774397]
["GO:0004660","protein farnesyltransferase activity","F",2,0.774683]
["GO:0005965","protein farnesyltransferase complex","C",2,0.774683]
["GO:0018347","protein amino acid farnesylation","P",2,0.774683]
["GO:0004857","enzyme inhibitor activity","F",5,0.774886]
["GO:0006665","sphingolipid metabolism","P",8,0.775032]
["GO:0030696","tRNA (m5U54) methyltransferase activity","F",1,0.775627]
["GO:0000752","agglutination during conjugation with cellular fusion","P",4,0.776062]
["GO:0045184","establishment of protein localization","P",2,0.776127]
["GO:0007532","regulation of transcription, mating-type specific","P",5,0.776658]
["GO:0004496","mevalonate kinase activity","F",1,0.777531]
["GO:0019344","cysteine biosynthesis","P",2,0.779148]
["GO:0004332","fructose-bisphosphate aldolase activity","F",1,0.779687]
["GO:0005977","glycogen metabolism","P",13,0.779696]
["GO:0006457","protein folding","P",55,0.78017]
["GO:0016237","microautophagy","P",6,0.780757]
["GO:0004661","protein geranylgeranyltransferase activity","F",2,0.781705]
["GO:0005953","CAAX-protein geranylgeranyltransferase complex","C",2,0.781705]
["GO:0004247","saccharolysin activity","F",1,0.782348]
["GO:0019395","fatty acid oxidation","P",2,0.783291]
["GO:0004252","serine-type endopeptidase activity","F",2,0.783317]
["GO:0045941","positive regulation of transcription","P",7,0.784679]
["GO:0030530","heterogeneous nuclear ribonucleoprotein complex","C",4,0.785221]
["GO:0006694","steroid biosynthesis","P",7,0.785267]
["GO:0006094","gluconeogenesis","P",15,0.785386]
["GO:0004422","hypoxanthine phosphoribosyltransferase activity","F",1,0.785403]
["GO:0046482","para-aminobenzoic acid metabolism","P",1,0.786771]
["GO:0046820","4-amino-4-deoxychorismate synthase activity","F",1,0.786771]
["GO:0004022","alcohol dehydrogenase activity","F",5,0.787]
["GO:0005981","regulation of glycogen catabolism","P",4,0.787204]
["GO:0016563","transcriptional activator activity","F",35,0.787221]
["GO:0016071","mRNA metabolism","P",4,0.787787]
["GO:0004655","porphobilinogen synthase activity","F",1,0.789516]
["GO:0004743","pyruvate kinase activity","F",2,0.789618]
["GO:0006490","oligosaccharide-lipid intermediate assembly","P",3,0.79003]
["GO:0030137","COPI-coated vesicle","C",12,0.791215]
["GO:0015197","peptide transporter activity","F",1,0.791955]
["GO:0015833","peptide transport","P",1,0.791955]
["GO:0005355","glucose transporter activity","F",14,0.792123]
["GO:0004558","alpha-glucosidase activity","F",3,0.792479]
["GO:0015410","manganese-transporting ATPase activity","F",1,0.792594]
["GO:0006412","protein biosynthesis","P",246,0.792642]
["GO:0000087","M phase of mitotic cell cycle","P",2,0.793779]
["GO:0008251","tRNA specific adenosine deaminase activity","F",3,0.794241]
["GO:0008295","spermidine biosynthesis","P",2,0.794475]
["GO:0006513","protein monoubiquitination","P",20,0.795696]
["GO:0015846","polyamine transport","P",9,0.796163]
["GO:0015809","L-arginine transport","P",1,0.796832]
["GO:0015819","L-lysine transport","P",1,0.796832]
["GO:0003978","UDP-glucose 4-epimerase activity","F",1,0.798193]
["GO:0006279","premeiotic DNA synthesis","P",4,0.79858]
["GO:0030866","cortical actin cytoskeleton organization and biogenesis","P",1,0.799027]
["GO:0008380","RNA splicing","P",5,0.799837]
["GO:0016532","superoxide dismutase copper chaperone activity","F",1,0.800021]
["GO:0003880","C-terminal protein carboxyl methyltransferase activity","F",2,0.80042]
["GO:0006139","nucleobase, nucleoside, nucleotide and nucleic acid metabolism","P",7,0.800423]
["GO:0004808","tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity","F",1,0.800516]
["GO:0006635","fatty acid beta-oxidation","P",9,0.800961]
["GO:0006355","regulation of transcription, DNA-dependent","P",29,0.801017]
["GO:0005754","proton-transporting ATP synthase, catalytic core (sensu Eukaryota)","C",2,0.801337]
["GO:0016788","hydrolase activity, acting on ester bonds","F",4,0.801339]
["GO:0005774","vacuolar membrane","C",30,0.801492]
["GO:0000007","low-affinity zinc ion transporter activity","F",1,0.803784]
["GO:0006831","low-affinity zinc ion transport","P",1,0.803784]
["GO:0004861","cyclin-dependent protein kinase inhibitor activity","F",2,0.804279]
["GO:0006032","chitin catabolism","P",1,0.804603]
["GO:0008843","endochitinase activity","F",1,0.804603]
["GO:0004315","3-oxoacyl-[acyl-carrier protein] synthase activity","F",1,0.805827]
["GO:0005247","voltage-gated chloride channel activity","F",1,0.8068]
["GO:0000304","response to singlet oxygen","P",2,0.807237]
["GO:0006351","transcription, DNA-dependent","P",1,0.807797]
["GO:0008299","isoprenoid biosynthesis","P",3,0.808463]
["GO:0015718","monocarboxylic acid transport","P",1,0.808992]
["GO:0005536","glucose binding","F",2,0.809147]
["GO:0001718","conversion of met-tRNAf to fmet-tRNA","P",1,0.811106]
["GO:0019415","acetate biosynthesis from carbon monoxide","P",1,0.811106]
["GO:0019653","purine fermentation","P",1,0.811106]
["GO:0046656","folic acid biosynthesis","P",1,0.811106]
["GO:0004783","sulfite reductase (NADPH) activity","F",2,0.811226]
["GO:0009337","sulfite reductase complex (NADPH)","C",2,0.811226]
["GO:0004737","pyruvate decarboxylase activity","F",4,0.811457]
["GO:0000743","nuclear migration during conjugation with cellular fusion","P",4,0.811827]
["GO:0042623","ATPase activity, coupled","F",2,0.81265]
["GO:0003923","GPI-anchor transamidase activity","F",5,0.81366]
["GO:0016255","attachment of GPI anchor to protein","P",5,0.81366]
["GO:0042765","GPI-anchor transamidase complex","C",5,0.81366]
["GO:0007050","cell cycle arrest","P",3,0.813663]
["GO:0004806","triacylglycerol lipase activity","F",2,0.813824]
["GO:0006183","GTP biosynthesis","P",2,0.814236]
["GO:0004766","spermidine synthase activity","F",1,0.814273]
["GO:0003992","acetylornithine transaminase activity","F",1,0.815298]
["GO:0005762","mitochondrial large ribosomal subunit","C",43,0.816824]
["GO:0051443","positive regulation of ubiquitin ligase activity","P",1,0.817183]
["GO:0007007","inner mitochondrial membrane organization and biogenesis","P",4,0.818454]
["GO:0000282","bud site selection","P",26,0.818529]
["GO:0006916","anti-apoptosis","P",1,0.819039]
["GO:0046459","short-chain fatty acid metabolism","P",2,0.819232]
["GO:0006538","glutamate catabolism","P",2,0.819255]
["GO:0015559","multidrug efflux pump activity","F",4,0.819423]
["GO:0004177","aminopeptidase activity","F",5,0.820056]
["GO:0007091","mitotic metaphase/anaphase transition","P",13,0.820297]
["GO:0018027","peptidyl-lysine di-methylation","P",1,0.820767]
["GO:0003756","protein disulfide isomerase activity","F",5,0.82128]
["GO:0004061","arylformamidase activity","F",1,0.82155]
["GO:0005619","spore wall (sensu Fungi)","C",7,0.821778]
["GO:0048471","perinuclear region","C",1,0.82245]
["GO:0045722","positive regulation of gluconeogenesis","P",2,0.822658]
["GO:0004758","serine C-palmitoyltransferase activity","F",2,0.822762]
["GO:0017059","serine C-palmitoyltransferase complex","C",2,0.822762]
["GO:0005788","endoplasmic reticulum lumen","C",6,0.823079]
["GO:0003843","1,3-beta-glucan synthase activity","F",3,0.823528]
["GO:0008236","serine-type peptidase activity","F",2,0.82375]
["GO:0005576","extracellular region","C",19,0.82378]
["GO:0051015","actin filament binding","F",6,0.824082]
["GO:0000018","regulation of DNA recombination","P",1,0.824109]
["GO:0051233","spindle midzone","C",4,0.824285]
["GO:0005385","zinc ion transporter activity","F",3,0.824704]
["GO:0015891","siderophore transport","P",3,0.825235]
["GO:0015114","phosphate transporter activity","F",3,0.825333]
["GO:0005094","Rho GDP-dissociation inhibitor activity","F",1,0.825373]
["GO:0018283","iron incorporation into metallo-sulfur cluster","P",1,0.82562]
["GO:0003895","gamma DNA-directed DNA polymerase activity","F",1,0.825626]
["GO:0006264","mitochondrial DNA replication","P",1,0.825626]
["GO:0016757","transferase activity, transferring glycosyl groups","F",7,0.825653]
["GO:0007535","donor selection","P",1,0.825965]
["GO:0005792","microsome","C",16,0.826033]
["GO:0003879","ATP phosphoribosyltransferase activity","F",1,0.826595]
["GO:0004316","3-oxoacyl-[acyl-carrier protein] reductase activity","F",2,0.828386]
["GO:0015175","neutral amino acid transporter activity","F",4,0.828817]
["GO:0015804","neutral amino acid transport","P",4,0.828817]
["GO:0000252","C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity","F",1,0.829403]
["GO:0000396","U2-type spliceosome conformational change to release U4 and U1","P",1,0.829781]
["GO:0006020","myo-inositol metabolism","P",4,0.830006]
["GO:0006749","glutathione metabolism","P",5,0.830477]
["GO:0004161","dimethylallyltranstransferase activity","F",1,0.830753]
["GO:0004337","geranyltranstransferase activity","F",1,0.830753]
["GO:0045337","farnesyl diphosphate biosynthesis","P",1,0.830753]
["GO:0006473","protein amino acid acetylation","P",9,0.831695]
["GO:0005623","cell","C",1,0.831869]
["GO:0031126","snoRNA 3'-end processing","P",3,0.832129]
["GO:0000293","ferric-chelate reductase activity","F",7,0.832341]
["GO:0005884","actin filament","C",5,0.832725]
["GO:0016567","protein ubiquitination","P",29,0.833983]
["GO:0006592","ornithine biosynthesis","P",4,0.834487]
["GO:0048025","negative regulation of nuclear mRNA splicing, via spliceosome","P",1,0.835197]
["GO:0000502","proteasome complex (sensu Eukaryota)","C",11,0.835238]
["GO:0006526","arginine biosynthesis","P",10,0.835317]
["GO:0006325","establishment and/or maintenance of chromatin architecture","P",17,0.835899]
["GO:0001300","chronological cell aging","P",3,0.836452]
["GO:0006631","fatty acid metabolism","P",13,0.837098]
["GO:0008614","pyridoxine metabolism","P",5,0.837588]
["GO:0006633","fatty acid biosynthesis","P",9,0.838196]
["GO:0004329","formate-tetrahydrofolate ligase activity","F",2,0.838323]
["GO:0004477","methenyltetrahydrofolate cyclohydrolase activity","F",2,0.838323]
["GO:0004488","methylenetetrahydrofolate dehydrogenase (NADP+) activity","F",2,0.838323]
["GO:0004196","saccharopepsin activity","F",1,0.83894]
["GO:0004122","cystathionine beta-synthase activity","F",1,0.839125]
["GO:0006241","CTP biosynthesis","P",1,0.839697]
["GO:0004823","leucine-tRNA ligase activity","F",2,0.839733]
["GO:0006429","leucyl-tRNA aminoacylation","P",2,0.839733]
["GO:0006846","acetate transport","P",1,0.839739]
["GO:0015123","acetate transporter activity","F",1,0.839739]
["GO:0003676","nucleic acid binding","F",8,0.839821]
["GO:0000749","response to pheromone during conjugation with cellular fusion","P",6,0.840375]
["GO:0042221","response to chemical stimulus","P",1,0.840804]
["GO:0000164","protein phosphatase type 1 complex","C",7,0.841148]
["GO:0008610","lipid biosynthesis","P",2,0.842785]
["GO:0006597","spermine biosynthesis","P",2,0.843041]
["GO:0015680","intracellular copper ion transport","P",6,0.843343]
["GO:0045143","homologous chromosome segregation","P",5,0.843746]
["GO:0031146","SCF-dependent proteasomal ubiquitin-dependent protein catabolism","P",7,0.844016]
["GO:0006520","amino acid metabolism","P",3,0.844232]
["GO:0000173","inactivation of MAPK activity during osmolarity sensing","P",5,0.8447]
["GO:0016538","cyclin-dependent protein kinase regulator activity","F",23,0.845049]
["GO:0004512","inositol-3-phosphate synthase activity","F",1,0.845145]
["GO:0007039","vacuolar protein catabolism","P",10,0.846211]
["GO:0015087","cobalt ion transporter activity","F",1,0.846221]
["GO:0019187","beta-1,4-mannosyltransferase activity","F",1,0.846789]
["GO:0004679","AMP-activated protein kinase activity","F",4,0.84679]
["GO:0008361","regulation of cell size","P",8,0.846893]
["GO:0009031","thiol peroxidase activity","F",1,0.847447]
["GO:0017005","tyrosyl-DNA phosophodiesterase activity","F",1,0.847676]
["GO:0005777","peroxisome","C",26,0.848619]
["GO:0016810","hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds","F",3,0.848735]
["GO:0008092","cytoskeletal protein binding","F",8,0.849595]
["GO:0004363","glutathione synthase activity","F",1,0.850128]
["GO:0045116","protein neddylation","P",6,0.850129]
["GO:0045140","inositol phosphoceramide synthase activity","F",1,0.850227]
["GO:0015892","iron-siderophore transport","P",5,0.850325]
["GO:0016478","negative regulation of translation","P",4,0.850581]
["GO:0006545","glycine biosynthesis","P",2,0.850745]
["GO:0019005","SCF ubiquitin ligase complex","C",9,0.851147]
["GO:0046624","sphingolipid transporter activity","F",1,0.851308]
["GO:0007034","vacuolar transport","P",8,0.851635]
["GO:0031310","intrinsic to vacuolar membrane","C",2,0.851659]
["GO:0003842","1-pyrroline-5-carboxylate dehydrogenase activity","F",1,0.851948]
["GO:0003883","CTP synthase activity","F",2,0.852151]
["GO:0000226","microtubule cytoskeleton organization and biogenesis","P",9,0.85332]
["GO:0003747","translation release factor activity","F",2,0.853355]
["GO:0015893","drug transport","P",4,0.854093]
["GO:0005783","endoplasmic reticulum","C",209,0.855224]
["GO:0006644","phospholipid metabolism","P",11,0.85544]
["GO:0005880","nuclear microtubule","C",6,0.855576]
["GO:0006098","pentose-phosphate shunt","P",6,0.855645]
["GO:0016281","eukaryotic translation initiation factor 4F complex","C",4,0.857311]
["GO:0006826","iron ion transport","P",5,0.858545]
["GO:0003729","mRNA binding","F",26,0.858845]
["GO:0015238","drug transporter activity","F",2,0.859491]
["GO:0017137","Rab GTPase binding","F",2,0.860027]
["GO:0000907","sulfonate dioxygenase activity","F",1,0.860052]
["GO:0004709","MAP kinase kinase kinase activity","F",4,0.860238]
["GO:0000288","mRNA catabolism, deadenylylation-dependent decay","P",10,0.860974]
["GO:0004629","phospholipase C activity","F",1,0.861115]
["GO:0030149","sphingolipid catabolism","P",1,0.861115]
["GO:0006672","ceramide metabolism","P",2,0.861419]
["GO:0017040","ceramidase activity","F",2,0.861419]
["GO:0004056","argininosuccinate lyase activity","F",1,0.86256]
["GO:0003724","RNA helicase activity","F",15,0.862839]
["GO:0008936","nicotinamidase activity","F",1,0.862948]
["GO:0004065","arylsulfatase activity","F",1,0.863686]
["GO:0018741","alkyl sulfatase activity","F",1,0.863686]
["GO:0018909","dodecyl sulfate metabolism","P",1,0.863686]
["GO:0019878","lysine biosynthesis via aminoadipic acid","P",8,0.86389]
["GO:0005724","nuclear telomeric heterochromatin","C",7,0.864319]
["GO:0006493","protein amino acid O-linked glycosylation","P",15,0.864364]
["GO:0042177","negative regulation of protein catabolism","P",1,0.864437]
["GO:0005938","cell cortex","C",10,0.865022]
["GO:0004152","dihydroorotate dehydrogenase activity","F",1,0.865146]
["GO:0004351","glutamate decarboxylase activity","F",1,0.865547]
["GO:0030050","vesicle transport along actin filament","P",1,0.8657]
["GO:0004372","glycine hydroxymethyltransferase activity","F",2,0.86592]
["GO:0004427","inorganic diphosphatase activity","F",2,0.866456]
["GO:0016040","glutamate synthase (NADH) activity","F",1,0.866722]
["GO:0031026","glutamate synthase complex","C",1,0.866722]
["GO:0006465","signal peptide processing","P",7,0.866936]
["GO:0019740","nitrogen utilization","P",6,0.86718]
["GO:0001101","response to acid","P",1,0.867826]
["GO:0015225","biotin transporter activity","F",1,0.867832]
["GO:0015878","biotin transport","P",1,0.867832]
["GO:0004479","methionyl-tRNA formyltransferase activity","F",1,0.868219]
["GO:0004802","transketolase activity","F",2,0.868516]
["GO:0010224","response to UV-B","P",1,0.868871]
["GO:0010225","response to UV-C","P",1,0.868871]
["GO:0003934","GTP cyclohydrolase I activity","F",1,0.86889]
["GO:0007109","cytokinesis, completion of separation","P",6,0.869124]
["GO:0008320","protein carrier activity","F",9,0.870767]
["GO:0005842","cytosolic large ribosomal subunit (sensu Eukaryota)","C",74,0.870962]
["GO:0005199","structural constituent of cell wall","F",9,0.871235]
["GO:0008298","intracellular mRNA localization","P",10,0.872233]
["GO:0030529","ribonucleoprotein complex","C",1,0.872452]
["GO:0003678","DNA helicase activity","F",14,0.872526]
["GO:0015129","lactate transporter activity","F",1,0.872831]
["GO:0015727","lactate transport","P",1,0.872831]
["GO:0005057","receptor signaling protein activity","F",1,0.872869]
["GO:0008277","regulation of G-protein coupled receptor protein signaling pathway","P",1,0.872869]
["GO:0016298","lipase activity","F",7,0.873307]
["GO:0000080","G1 phase of mitotic cell cycle","P",3,0.874479]
["GO:0006467","protein thiol-disulfide exchange","P",2,0.874785]
["GO:0003982","UTP-hexose-1-phosphate uridylyltransferase activity","F",1,0.875098]
["GO:0008104","protein localization","P",5,0.875444]
["GO:0000048","peptidyltransferase activity","F",3,0.875823]
["GO:0016768","spermine synthase activity","F",1,0.87603]
["GO:0006505","GPI anchor metabolism","P",1,0.876772]
["GO:0000356","U2-type catalytic spliceosome formation for first transesterification step","P",1,0.877147]
["GO:0016667","oxidoreductase activity, acting on sulfur group of donors","F",1,0.877691]
["GO:0031011","INO80 complex","C",11,0.877866]
["GO:0000169","activation of MAPK activity during osmolarity sensing","P",1,0.879886]
["GO:0010142","farnesyl diphosphate biosynthesis, mevalonate pathway","P",1,0.880286]
["GO:0030508","thiol-disulfide exchange intermediate activity","F",8,0.882405]
["GO:0017171","serine hydrolase activity","F",6,0.882447]
["GO:0004476","mannose-6-phosphate isomerase activity","F",1,0.882733]
["GO:0009743","response to carbohydrate stimulus","P",1,0.883199]
["GO:0010032","meiotic chromosome condensation","P",2,0.883487]
["GO:0005086","ARF guanyl-nucleotide exchange factor activity","F",5,0.883963]
["GO:0015908","fatty acid transport","P",3,0.884398]
["GO:0042800","histone lysine N-methyltransferase activity (H3-K4 specific)","F",8,0.884617]
["GO:0048188","COMPASS complex","C",8,0.884617]
["GO:0042406","extrinsic to endoplasmic reticulum membrane","C",2,0.885765]
["GO:0008233","peptidase activity","F",7,0.885883]
["GO:0000328","vacuolar lumen (sensu Fungi)","C",5,0.886846]
["GO:0004126","cytidine deaminase activity","F",1,0.887977]
["GO:0006216","cytidine catabolism","P",1,0.887977]
["GO:0006217","deoxycytidine catabolism","P",1,0.887977]
["GO:0031371","ubiquitin conjugating enzyme complex","C",2,0.888275]
["GO:0030479","actin cortical patch","C",40,0.888628]
["GO:0042144","vacuole fusion, non-autophagic","P",12,0.889742]
["GO:0045011","actin cable formation","P",5,0.889953]
["GO:0003949","1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity","F",1,0.889968]
["GO:0000152","nuclear ubiquitin ligase complex","C",6,0.890124]
["GO:0005759","mitochondrial matrix","C",57,0.892305]
["GO:0030042","actin filament depolymerization","P",2,0.892479]
["GO:0008487","prenyl-dependent CAAX protease activity","F",2,0.892834]
["GO:0019654","acetate fermentation","P",1,0.892887]
["GO:0004815","aspartate-tRNA ligase activity","F",2,0.893082]
["GO:0048487","beta-tubulin binding","F",2,0.893102]
["GO:0015630","microtubule cytoskeleton","C",1,0.893286]
["GO:0005384","manganese ion transporter activity","F",5,0.893346]
["GO:0045009","chitosome","C",2,0.894067]
["GO:0015450","protein translocase activity","F",1,0.894537]
["GO:0050821","protein stabilization","P",1,0.894537]
["GO:0009164","nucleoside catabolism","P",1,0.894583]
["GO:0017111","nucleoside-triphosphatase activity","F",1,0.894583]
["GO:0003700","transcription factor activity","F",58,0.897055]
["GO:0045182","translation regulator activity","F",8,0.897446]
["GO:0000723","telomere maintenance","P",17,0.89745]
["GO:0006865","amino acid transport","P",13,0.898774]
["GO:0004100","chitin synthase activity","F",3,0.898983]
["GO:0005680","anaphase-promoting complex","C",16,0.899066]
["GO:0005978","glycogen biosynthesis","P",6,0.899564]
["GO:0003844","1,4-alpha-glucan branching enzyme activity","F",1,0.900927]
["GO:0005737","cytoplasm","C",1260,0.901624]
["GO:0006506","GPI anchor biosynthesis","P",16,0.90194]
["GO:0030026","manganese ion homeostasis","P",5,0.902286]
["GO:0008806","carboxymethylenebutenolidase activity","F",1,0.902614]
["GO:0000268","peroxisome targeting sequence binding","F",3,0.903065]
["GO:0005315","inorganic phosphate transporter activity","F",4,0.903196]
["GO:0004697","protein kinase C activity","F",1,0.903796]
["GO:0004820","glycine-tRNA ligase activity","F",2,0.904126]
["GO:0006426","glycyl-tRNA aminoacylation","P",2,0.904126]
["GO:0042175","nuclear envelope-endoplasmic reticulum network","C",13,0.904523]
["GO:0006570","tyrosine metabolism","P",1,0.905328]
["GO:0008977","prephenate dehydrogenase activity","F",1,0.905328]
["GO:0004043","L-aminoadipate-semialdehyde dehydrogenase activity","F",1,0.905892]
["GO:0046689","response to mercury ion","P",1,0.906366]
["GO:0017057","6-phosphogluconolactonase activity","F",4,0.907652]
["GO:0016428","tRNA (cytosine-5-)-methyltransferase activity","F",1,0.907721]
["GO:0004609","phosphatidylserine decarboxylase activity","F",2,0.907744]
["GO:0045015","HDEL sequence binding","F",1,0.908816]
["GO:0005756","proton-transporting ATP synthase, central stalk (sensu Eukaryota)","C",3,0.909114]
["GO:0004516","nicotinate phosphoribosyltransferase activity","F",1,0.910083]
["GO:0030427","site of polarized growth","C",8,0.911486]
["GO:0005822","inner plaque of spindle pole body","C",4,0.911707]
["GO:0006814","sodium ion transport","P",2,0.913033]
["GO:0005787","signal peptidase complex","C",4,0.914007]
["GO:0048309","endoplasmic reticulum inheritance","P",2,0.914705]
["GO:0015079","potassium ion transporter activity","F",2,0.915053]
["GO:0048026",{"$error":"#N/A"},{"$error":"#N/A"},1,0.916047]
["GO:0004169","dolichyl-phosphate-mannose-protein mannosyltransferase activity","F",6,0.916535]
["GO:0045121","lipid raft","C",6,0.9173]
["GO:0006206","pyrimidine base metabolism","P",1,0.917348]
["GO:0008252","nucleotidase activity","F",1,0.917348]
["GO:0008033","tRNA processing","P",16,0.917608]
["GO:0019778","APG12 activating enzyme activity","F",1,0.917698]
["GO:0019779","APG8 activating enzyme activity","F",1,0.917698]
["GO:0016431","tRNA (uridine) methyltransferase activity","F",1,0.918881]
["GO:0004506","squalene monooxygenase activity","F",1,0.919074]
["GO:0008144","drug binding","F",1,0.919074]
["GO:0030447","filamentous growth","P",23,0.920358]
["GO:0007005","mitochondrion organization and biogenesis","P",32,0.920643]
["GO:0005078","MAP-kinase scaffold activity","F",2,0.920714]
["GO:0006808","regulation of nitrogen utilization","P",8,0.920769]
["GO:0001321","age-dependent general metabolic decline during replicative cell aging","P",1,0.920912]
["GO:0005545","phosphatidylinositol binding","F",6,0.921017]
["GO:0006071","glycerol metabolism","P",3,0.921111]
["GO:0004081","bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity","F",1,0.921559]
["GO:0019210","kinase inhibitor activity","F",1,0.921715]
["GO:0016032","viral life cycle","P",2,0.922314]
["GO:0000136","alpha-1,6-mannosyltransferase complex","C",6,0.922727]
["GO:0003711","transcriptional elongation regulator activity","F",5,0.922977]
["GO:0000026","alpha-1,2-mannosyltransferase activity","F",6,0.923035]
["GO:0007031","peroxisome organization and biogenesis","P",29,0.923441]
["GO:0006283","transcription-coupled nucleotide-excision repair","P",1,0.92425]
["GO:0030120","vesicle coat","C",2,0.924347]
["GO:0008892","guanine deaminase activity","F",1,0.924708]
["GO:0046098","guanine metabolism","P",1,0.924708]
["GO:0005342","organic acid transporter activity","F",3,0.926811]
["GO:0016074","snoRNA metabolism","P",5,0.926972]
["GO:0000209","protein polyubiquitination","P",20,0.928292]
["GO:0006259","DNA metabolism","P",13,0.928449]
["GO:0030007","potassium ion homeostasis","P",4,0.929132]
["GO:0004795","threonine synthase activity","F",1,0.929283]
["GO:0004610","phosphoacetylglucosamine mutase activity","F",1,0.929309]
["GO:0006045","N-acetylglucosamine biosynthesis","P",1,0.929309]
["GO:0006839","mitochondrial transport","P",6,0.929751]
["GO:0004825","methionine-tRNA ligase activity","F",2,0.930771]
["GO:0006810","transport","P",50,0.931226]
["GO:0004526","ribonuclease P activity","F",10,0.93156]
["GO:0003716","RNA polymerase I transcription termination factor activity","F",1,0.932295]
["GO:0006363","transcription termination from RNA polymerase I promoter","P",1,0.932295]
["GO:0008453","alanine-glyoxylate transaminase activity","F",1,0.933191]
["GO:0009410","response to xenobiotic stimulus","P",5,0.933716]
["GO:0008202","steroid metabolism","P",2,0.933853]
["GO:0006666","3-keto-sphinganine metabolism","P",2,0.934354]
["GO:0008531","riboflavin kinase activity","F",1,0.93511]
["GO:0009398","FMN biosynthesis","P",1,0.93511]
["GO:0000172","ribonuclease MRP complex","C",10,0.935439]
["GO:0000122","negative regulation of transcription from RNA polymerase II promoter","P",31,0.935693]
["GO:0016226","iron-sulfur cluster assembly","P",8,0.937096]
["GO:0008079","translation termination factor activity","F",1,0.937295]
["GO:0045910","negative regulation of DNA recombination","P",2,0.938426]
["GO:0004622","lysophospholipase activity","F",4,0.938673]
["GO:0003994","aconitate hydratase activity","F",2,0.938903]
["GO:0019243","methylglyoxal catabolism to D-lactate","P",3,0.93928]
["GO:0015489","putrescine transporter activity","F",1,0.939296]
["GO:0015495","gamma-aminobutyric acid:hydrogen symporter activity","F",1,0.939296]
["GO:0015847","putrescine transport","P",1,0.939296]
["GO:0005215","transporter activity","F",36,0.939719]
["GO:0015343","siderophore-iron transporter activity","F",2,0.940359]
["GO:0000324","vacuole (sensu Fungi)","C",75,0.940369]
["GO:0000165","MAPKKK cascade","P",4,0.941209]
["GO:0003919","FMN adenylyltransferase activity","F",2,0.942155]
["GO:0004540","ribonuclease activity","F",4,0.942472]
["GO:0043328","protein targeting to vacuole during ubiquitin-dependent protein catabolism via the MVB pathway","P",3,0.942507]
["GO:0007165","signal transduction","P",36,0.942927]
["GO:0051228","mitotic spindle disassembly","P",2,0.94299]
["GO:0004747","ribokinase activity","F",1,0.943064]
["GO:0006014","D-ribose metabolism","P",1,0.943064]
["GO:0045552","dihydrokaempferol 4-reductase activity","F",3,0.943119]
["GO:0031072","heat shock protein binding","F",1,0.943331]
["GO:0004826","phenylalanine-tRNA ligase activity","F",3,0.943428]
["GO:0008796","bis(5'-nucleosyl)-tetraphosphatase activity","F",2,0.943544]
["GO:0046655","folic acid metabolism","P",1,0.943724]
["GO:0003977","UDP-N-acetylglucosamine diphosphorylase activity","F",1,0.946607]
["GO:0031145","anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolism","P",13,0.946701]
["GO:0015840","urea transport","P",2,0.946728]
["GO:0016772","transferase activity, transferring phosphorus-containing groups","F",3,0.94702]
["GO:0005506","iron ion binding","F",1,0.947876]
["GO:0004416","hydroxyacylglutathione hydrolase activity","F",2,0.948093]
["GO:0004829","threonine-tRNA ligase activity","F",2,0.948321]
["GO:0004312","fatty-acid synthase activity","F",1,0.948706]
["GO:0005484","SNAP receptor activity","F",2,0.949925]
["GO:0003849","3-deoxy-7-phosphoheptulonate synthase activity","F",2,0.94997]
["GO:0006445","regulation of translation","P",4,0.950299]
["GO:0030428","cell septum","C",1,0.950415]
["GO:0030138","COPII-coated vesicle","C",16,0.951042]
["GO:0005052","peroxisome targeting signal-1 binding","F",1,0.951076]
["GO:0004144","diacylglycerol O-acyltransferase activity","F",1,0.951856]
["GO:0008808","cardiolipin synthase activity","F",1,0.95221]
["GO:0030476","spore wall assembly (sensu Fungi)","P",39,0.953281]
["GO:0000928","gamma-tubulin complex (sensu Saccharomyces)","C",3,0.953936]
["GO:0046294","formaldehyde catabolism","P",2,0.953999]
["GO:0009826","unidimensional cell growth","P",1,0.954136]
["GO:0015105",{"$error":"#N/A"},{"$error":"#N/A"},1,0.954369]
["GO:0015700",{"$error":"#N/A"},{"$error":"#N/A"},1,0.954369]
["GO:0008519","ammonium transporter activity","F",6,0.955124]
["GO:0015696","ammonium transport","P",6,0.955124]
["GO:0000038","very-long-chain fatty acid metabolism","P",2,0.955207]
["GO:0016787","hydrolase activity","F",6,0.95544]
["GO:0000090","mitotic anaphase","P",1,0.955679]
["GO:0015824","L-proline transport","P",1,0.956785]
["GO:0016247","channel regulator activity","F",1,0.956785]
["GO:0004733","pyridoxamine-phosphate oxidase activity","F",1,0.956935]
["GO:0004482","mRNA (guanine-N7-)-methyltransferase activity","F",1,0.957024]
["GO:0019358","nicotinate nucleotide salvage","P",2,0.957439]
["GO:0004605","phosphatidate cytidylyltransferase activity","F",1,0.958035]
["GO:0006655","phosphatidylglycerol biosynthesis","P",1,0.958035]
["GO:0006658","phosphatidylserine metabolism","P",1,0.958035]
["GO:0015999","eta DNA polymerase activity","F",1,0.958308]
["GO:0019985","bypass DNA synthesis","P",1,0.958308]
["GO:0008670","2,4-dienoyl-CoA reductase (NADPH) activity","F",1,0.959024]
["GO:0009062","fatty acid catabolism","P",1,0.959024]
["GO:0001406","glycerophosphodiester transporter activity","F",1,0.959383]
["GO:0001407","glycerophosphodiester transport","P",1,0.959383]
["GO:0015392","cytosine-purine permease activity","F",3,0.960155]
["GO:0005739","mitochondrion","C",602,0.960381]
["GO:0007569","cell aging","P",3,0.960659]
["GO:0009073","aromatic amino acid family biosynthesis","P",5,0.960893]
["GO:0015127","bilirubin transporter activity","F",2,0.960991]
["GO:0015723","bilirubin transport","P",2,0.960991]
["GO:0004759","serine esterase activity","F",1,0.961224]
["GO:0045117","azole transport","P",1,0.961396]
["GO:0045118","azole transporter activity","F",1,0.961396]
["GO:0030488","tRNA methylation","P",14,0.961451]
["GO:0008139","nuclear localization sequence binding","F",3,0.961586]
["GO:0009102","biotin biosynthesis","P",4,0.961752]
["GO:0030071","regulation of mitotic metaphase/anaphase transition","P",2,0.962688]
["GO:0006562","proline catabolism","P",3,0.96293]
["GO:0015802","basic amino acid transport","P",6,0.962995]
["GO:0006828","manganese ion transport","P",7,0.963106]
["GO:0009055","electron carrier activity","F",5,0.96437]
["GO:0007025","beta-tubulin folding","P",3,0.964575]
["GO:0009237",{"$error":"#N/A"},{"$error":"#N/A"},1,0.965071]
["GO:0004856","xylulokinase activity","F",1,0.965203]
["GO:0005998","xylulose catabolism","P",1,0.965203]
["GO:0006817","phosphate transport","P",10,0.965218]
["GO:0017173","DRAP deaminase activity","F",1,0.965684]
["GO:0004934","mating-type alpha-factor pheromone receptor activity","F",1,0.96595]
["GO:0030031","cell projection biogenesis","P",1,0.96595]
["GO:0042149","cellular response to glucose starvation","P",2,0.966347]
["GO:0000506","glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex","C",4,0.966348]
["GO:0008194","UDP-glycosyltransferase activity","F",4,0.966348]
["GO:0003954","NADH dehydrogenase activity","F",2,0.966484]
["GO:0004107","chorismate synthase activity","F",1,0.966528]
["GO:0042602","flavin reductase activity","F",1,0.966528]
["GO:0008372","cellular component unknown","C",640,0.966897]
["GO:0009409","response to cold","P",2,0.967138]
["GO:0004518","nuclease activity","F",2,0.967398]
["GO:0006431","methionyl-tRNA aminoacylation","P",3,0.968211]
["GO:0004608","phosphatidylethanolamine N-methyltransferase activity","F",1,0.968335]
["GO:0006970","response to osmotic stress","P",33,0.968536]
["GO:0015319","sodium:inorganic phosphate symporter activity","F",1,0.968608]
["GO:0047484","regulation of response to osmotic stress","P",1,0.969129]
["GO:0000943",{"$error":"#N/A"},{"$error":"#N/A"},3,0.970409]
["GO:0003964",{"$error":"#N/A"},{"$error":"#N/A"},3,0.970409]
["GO:0006319",{"$error":"#N/A"},{"$error":"#N/A"},3,0.970409]
["GO:0003852","2-isopropylmalate synthase activity","F",2,0.970694]
["GO:0018216","peptidyl-arginine methylation","P",1,0.971219]
["GO:0006435","threonyl-tRNA aminoacylation","P",1,0.971532]
["GO:0008559","xenobiotic-transporting ATPase activity","F",5,0.972136]
["GO:0042775","ATP synthesis coupled electron transport (sensu Eukaryota)","P",1,0.972168]
["GO:0005098","Ran GTPase activator activity","F",1,0.972605]
["GO:0016591","DNA-directed RNA polymerase II, holoenzyme","C",6,0.972652]
["GO:0007323","peptide pheromone maturation","P",8,0.972822]
["GO:0000773","phosphatidyl-N-methylethanolamine N-methyltransferase activity","F",1,0.973545]
["GO:0005830","cytosolic ribosome (sensu Eukaryota)","C",16,0.9737]
["GO:0016649","oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor","F",1,0.973724]
["GO:0019677","NAD catabolism","P",1,0.973724]
["GO:0016023","cytoplasmic membrane-bound vesicle","C",7,0.973904]
["GO:0004357","glutamate-cysteine ligase activity","F",1,0.974031]
["GO:0000248","C-5 sterol desaturase activity","F",1,0.975243]
["GO:0004930","G-protein coupled receptor activity","F",1,0.975812]
["GO:0007186","G-protein coupled receptor protein signaling pathway","P",1,0.975812]
["GO:0005773","vacuole","C",12,0.975995]
["GO:0015171","amino acid transporter activity","F",9,0.97651]
["GO:0000002","mitochondrial genome maintenance","P",27,0.976964]
["GO:0010008","endosome membrane","C",3,0.976977]
["GO:0006561","proline biosynthesis","P",3,0.97734]
["GO:0004933","mating-type a-factor pheromone receptor activity","F",1,0.977659]
["GO:0000121","glycerol-1-phosphatase activity","F",2,0.97797]
["GO:0006114","glycerol biosynthesis","P",2,0.97797]
["GO:0019211","phosphatase activator activity","F",1,0.978606]
["GO:0004435","phosphoinositide phospholipase C activity","F",1,0.979041]
["GO:0005386","carrier activity","F",3,0.979315]
["GO:0000171","ribonuclease MRP activity","F",9,0.979525]
["GO:0007188","G-protein signaling, coupled to cAMP nucleotide second messenger","P",2,0.979546]
["GO:0004577","N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity","F",2,0.979831]
["GO:0031211","palmitoyltransferase complex","C",2,0.97984]
["GO:0048250","mitochondrial iron ion transport","P",2,0.979889]
["GO:0004091","carboxylesterase activity","F",1,0.980402]
["GO:0042124","1,3-beta-glucanosyltransferase activity","F",5,0.980823]
["GO:0016303","phosphatidylinositol 3-kinase activity","F",3,0.981381]
["GO:0006621","protein retention in ER","P",6,0.981438]
["GO:0040008","regulation of growth","P",2,0.981523]
["GO:0031494","regulation of mating type switching","P",1,0.981568]
["GO:0008654","phospholipid biosynthesis","P",13,0.981576]
["GO:0006656","phosphatidylcholine biosynthesis","P",7,0.981958]
["GO:0006750","glutathione biosynthesis","P",2,0.982466]
["GO:0004810","tRNA adenylyltransferase activity","F",1,0.982589]
["GO:0015646","permease activity","F",2,0.982744]
["GO:0006345","loss of chromatin silencing","P",1,0.983423]
["GO:0043035","chromatin insulator sequence binding","F",1,0.983423]
["GO:0005381","iron ion transporter activity","F",6,0.983629]
["GO:0004376","glycolipid mannosyltransferase activity","F",1,0.984294]
["GO:0009003","signal peptidase activity","F",2,0.984604]
["GO:0000168","activation of MAPKK activity during osmolarity sensing","P",2,0.985533]
["GO:0004015","adenosylmethionine-8-amino-7-oxononanoate transaminase activity","F",1,0.985689]
["GO:0015849","organic acid transport","P",1,0.986221]
["GO:0016491","oxidoreductase activity","F",10,0.986593]
["GO:0008053","mitochondrial fusion","P",4,0.986823]
["GO:0000117","G2/M-specific transcription in mitotic cell cycle","P",1,0.986922]
["GO:0015620","ferric-enterobactin transporter activity","F",1,0.987389]
["GO:0015685","ferric-enterobactin transport","P",1,0.987389]
["GO:0004640","phosphoribosylanthranilate isomerase activity","F",1,0.987622]
["GO:0008451","X-Pro aminopeptidase activity","F",2,0.987677]
["GO:0005655","nucleolar ribonuclease P complex","C",9,0.987757]
["GO:0008415","acyltransferase activity","F",4,0.987769]
["GO:0012510","trans-Golgi network transport vesicle membrane","C",1,0.987982]
["GO:0019829","cation-transporting ATPase activity","F",1,0.987982]
["GO:0006880","intracellular sequestering of iron ion","P",2,0.988142]
["GO:0015174","basic amino acid transporter activity","F",4,0.988353]
["GO:0015125","bile acid transporter activity","F",1,0.98857]
["GO:0015721","bile acid transport","P",1,0.98857]
["GO:0004644","phosphoribosylglycinamide formyltransferase activity","F",1,0.988727]
["GO:0046084","adenine biosynthesis","P",1,0.988727]
["GO:0004373","glycogen (starch) synthase activity","F",2,0.989337]
["GO:0005811","lipid particle","C",29,0.991148]
["GO:0016020","membrane","C",82,0.991832]
["GO:0045876",{"$error":"#N/A"},{"$error":"#N/A"},1,0.992849]
["GO:0004636","phosphoribosyl-ATP diphosphatase activity","F",2,0.992968]
["GO:0009408","response to heat","P",16,0.993021]
["GO:0004350","glutamate-5-semialdehyde dehydrogenase activity","F",1,0.993333]
["GO:0000724","double-strand break repair via homologous recombination","P",5,0.993405]
["GO:0030332","cyclin binding","F",1,0.993701]
["GO:0019541","propionate metabolism","P",5,0.993909]
["GO:0005628","prospore membrane","C",16,0.994455]
["GO:0016021","integral to membrane","C",94,0.994809]
["GO:0004057","arginyltransferase activity","F",1,0.995634]
["GO:0016598","protein arginylation","P",1,0.995634]
["GO:0006080","mannan metabolism","P",2,0.996056]
["GO:0004702","receptor signaling protein serine/threonine kinase activity","F",2,0.996184]
["GO:0030173","integral to Golgi membrane","C",14,0.996213]
["GO:0000004","biological process unknown","P",1211,0.996283]
["GO:0007231","osmosensory signaling pathway","P",6,0.996483]
["GO:0015184","L-cystine transporter activity","F",1,0.9967]
["GO:0015811","L-cystine transport","P",1,0.9967]
["GO:0046029","mannitol dehydrogenase activity","F",1,0.997033]
["GO:0004016","adenylate cyclase activity","F",1,0.997536]
["GO:0018318","protein amino acid palmitoylation","P",5,0.997559]
["GO:0019706","protein-cysteine S-palmitoleyltransferase activity","F",5,0.997559]
["GO:0005782","peroxisomal matrix","C",13,0.997589]
["GO:0008608","attachment of spindle microtubules to kinetochore","P",3,0.997619]
["GO:0000250","lanosterol synthase activity","F",1,0.99776]
["GO:0015086","cadmium ion transporter activity","F",1,0.998043]
["GO:0015691","cadmium ion transport","P",1,0.998043]
["GO:0030968","unfolded protein response","P",1,0.998104]
["GO:0005275",{"$error":"#N/A"},{"$error":"#N/A"},1,0.998509]
["GO:0015837",{"$error":"#N/A"},{"$error":"#N/A"},1,0.998509]
["GO:0042132","fructose-bisphosphatase activity","F",1,0.998839]
["GO:0004553","hydrolase activity, hydrolyzing O-glycosyl compounds","F",2,0.998885]
["GO:0043130","ubiquitin binding","F",3,0.998974]
["GO:0030176","integral to endoplasmic reticulum membrane","C",23,0.999303]
["GO:0004860","protein kinase inhibitor activity","F",3,0.99953]
["GO:0009277","cell wall (sensu Fungi)","C",84,0.999607]
["GO:0005886","plasma membrane","C",189,0.999922]

{"sheet":"Reporter-Metabolites","index":2,"n_rows":689,"n_cols":3,"rows_kept":689,"flags":["formulas_cached_only"]}
["Complete list of reporter metabolites"]
[]
["Metabolite","Number of neighbors","P-value"]
["Zymosterol",3,0.000194881]
["5-Amino-6-(5'-phosphoribosylamino)uracil",1,0.00233875]
["5-Amino-6-(5'-phosphoribitylamino)uracil",1,0.00233875]
["AMP",38,0.00372362]
["4-Methylzymsterol",2,0.00586351]
["L-Glutamyl-tRNA(Glu)",1,0.00833222]
["Isocitrate",5,0.0088569]
["Ethanolamine",1,0.00991082]
["S-Adenosyl-L-methionineM",2,0.0131707]
["S-Adenosyl-L-homocysteineM",2,0.0131707]
["Aminoimidazole ribotide",2,0.0160622]
["Oxalosuccinate",2,0.0208351]
["4-Amino-5-hydroxymethyl-2-methylpyrimidine",3,0.0243408]
["4-Amino-2-methyl-5-phosphomethylpyrimidine",3,0.0243408]
["2,5-Diamino-6-hydroxy-4-(5'-phosphoribosylamino)-pyrimidine",2,0.0248226]
["4,4-Dimethylzymosterol",2,0.0248257]
["2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate",2,0.0260145]
["NAxt",1,0.0280134]
["Sodium",1,0.0280134]
["Uroporphyrinogen III",3,0.0289127]
["dCMP",1,0.0338078]
["ERGOSTxt",1,0.0347071]
["ZYMSTxt",1,0.0347071]
["myo-Inositol",5,0.0379014]
["Ethanolamine phosphate",3,0.0433236]
["D-Glucosamine 6-phosphate",3,0.044531]
["dCTP",2,0.0455648]
["5-MethyltetrahydrofolateM",2,0.0470787]
["4,4-Dimethylcholesta-8,14,24-trienol",2,0.0483813]
["Hydroxymethylbilane",2,0.0484794]
["Sirohydrochlorin",1,0.0525848]
["Dihydrofolate",2,0.0526965]
["3-Phosphoserine",2,0.0579441]
["2-Nonaprenyl-6-methoxy-1,4-benzoquinoneM",1,0.0581398]
["2,3-Bisphospho-D-glycerate",1,0.058589]
["dTMP",2,0.0628059]
["2-Amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine",3,0.0701389]
["Pyrophosphate",60,0.0717101]
["2-Phospho-D-glycerate",6,0.0722793]
["5-Phosphoribosylamine",2,0.074689]
["D-Sorbitol",2,0.0801931]
["Adenosine 3',5'-bisphosphate",3,0.0813684]
["Phosphatidylserine",2,0.081659]
["dUMP",4,0.081803]
["dUTP",3,0.0854301]
["NADP+M",16,0.0865144]
["3-Demethylubiquinone-9M",2,0.0873291]
["2-Nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinoneM",2,0.0873494]
["2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine",1,0.0955482]
["Glycolaldehyde",1,0.0955482]
["2-Amino-7,8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine",1,0.0955482]
["4-Aminobenzoate",1,0.0955482]
["Dihydropteroate",1,0.0955482]
["Deamino-NAD+",2,0.0985941]
["Deamino-NAD+M",2,0.0985941]
["NH3",32,0.100642]
["L-Formylkynurenine",1,0.100748]
["Protoporphyrinogen IXM",1,0.101716]
["Fecosterol",2,0.105869]
["Ergosterol",2,0.105884]
["CoA",28,0.107754]
["1,3-Diaminopropane",1,0.108473]
["2-Dehydropantoate",2,0.108829]
["NADP+",44,0.110025]
["3-Nonaprenyl-4-hydroxybenzoate",8,0.113321]
["Tetradecenoyl-[acyl-carrier protein]",1,0.11592]
["ATP",113,0.117325]
["MalateM",5,0.121202]
["Orotidine 5'-phosphate",3,0.122189]
["Sphinganine 1-phosphate",5,0.122792]
["Acetoacetyl-CoA",2,0.126192]
["Melibiose",1,0.126369]
["alpha-D-Fucoside",1,0.126369]
["Raffinose",1,0.126369]
["Sucrose",1,0.126369]
["1-alpha-D-Galactosyl-myo-inositol",1,0.126369]
["Epimelibiose",1,0.126369]
["Galactosylglycerol",1,0.126369]
["Melibiitol",1,0.126369]
["NAD+M",19,0.129512]
["OxalosuccinateM",1,0.130008]
["2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine",2,0.13123]
["ITP",2,0.131675]
["IDP",2,0.131675]
["tRNA(Arg)",2,0.132899]
["L-Arginyl-tRNA(Arg)",2,0.132899]
["Acetyl-CoA",19,0.13703]
["PhosphoenolpyruvateM",1,0.137157]
["L-Aspartate 4-semialdehyde",2,0.138193]
["FADH2M",5,0.138627]
["all-trans-Nonaprenyl diphosphate",7,0.139864]
["Oxidized thioredoxin",4,0.14114]
["Reduced thioredoxin",4,0.14114]
["N(pai)-Methyl-L-histidine",1,0.141856]
["O-Acetyl-L-serine",1,0.147185]
["2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate",2,0.147418]
["alpha-D-Mannose 1-phosphate",2,0.148164]
["Adenosine",5,0.149137]
["D-Fructose 2,6-bisphosphate",3,0.151493]
["Reduced flavoprotein",1,0.154069]
["Oxidized flavoprotein",1,0.154069]
["3-Phospho-D-glycerate",6,0.15804]
["3-Carboxy-4-methyl-2-oxopentanoate",2,0.158404]
["Citrate",2,0.15913]
["MIxt",2,0.159979]
["Oxidized thioredoxinM",1,0.161268]
["Reduced thioredoxinM",1,0.161268]
["Succinyl-CoAM",3,0.161753]
["Sphinganine",6,0.162263]
["CO2",37,0.162766]
["a Long-chain carboxylic acid",4,0.16334]
["GDPmannose",11,0.164588]
["3'-Phosphoadenylylsulfate",2,0.166755]
["L-SerineM",2,0.167046]
["D-Arabinose",1,0.167383]
["D-Arabinono-1,4-lactone",1,0.167383]
["OxygenM",2,0.168758]
["NADPH",41,0.169834]
["Dolichol",1,0.169854]
["4-Phospho-L-aspartate",2,0.170716]
["NADPHM",13,0.170788]
["(R)-2-Oxoisovalerate",2,0.171497]
["Acyl-carrier protein",4,0.17155]
["FADM",6,0.17169]
["dTDP",2,0.174739]
["(S)-LactaldehydeM",1,0.17878]
["N-Acetyl-D-glucosamine 6-phosphate",2,0.178919]
["Intermediate_Methylzymosterol_II",2,0.187273]
["Intermediate_Zymosterol_II",2,0.187273]
["DihydrofolateM",1,0.187966]
["D-Glucose 1-phosphate",7,0.191376]
["dCDP",2,0.193985]
["1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate",2,0.196143]
["2-Nonaprenyl-6-hydroxyphenol",1,0.198069]
["2-Nonaprenyl-6-methoxyphenol",1,0.198069]
["Xanthosine 5'-phosphate",7,0.198229]
["N6-(1,2-Dicarboxyethyl)-AMP",2,0.198509]
["5-Amino-6-ribitylamino-2,4 (1H, 3H)-pyrimidinedione",2,0.201337]
["L-3,4-Dihydroxy-2-butanone 4-phosphate",2,0.201337]
["6,7-Dimethyl-8-(1-D-ribityl)lumazine",2,0.201337]
["1-Phosphatidyl-1D-myo-inositol 4-phosphate",4,0.202199]
["NH3M",3,0.202451]
["5,10-Methenyltetrahydrofolate",2,0.203502]
["Thiamin diphosphate",1,0.204538]
["Thiamin triphosphate",1,0.204538]
["H+M",9,0.204901]
["Decanoyl-[acp]",2,0.205521]
["Dodecanoyl-[acyl-carrier protein]",2,0.205521]
["Myristoyl-[acyl-carrier protein]",2,0.205521]
["Hexadecanoyl-[acp]",2,0.205521]
["Palmitoyl-[acyl-carrier protein]",2,0.205521]
["Stearoyl-[acyl-carrier protein]",2,0.205521]
["Oleoyl-[acyl-carrier protein]",2,0.205521]
["Linolenoyl-[acyl-carrier protein]",2,0.205521]
["2-Isopropylmalate",2,0.211695]
["CDPethanolamine",2,0.219167]
["CDP",4,0.226092]
["4-Hydroxybenzoate",9,0.226127]
["(S)-1-Pyrroline-5-carboxylateM",1,0.226464]
["L-ProlineM",1,0.226464]
["Succinate",7,0.226806]
["5,10-Methylenetetrahydrofolate",6,0.23075]
["(S)-3-Hydroxy-3-methylglutaryl-CoA",3,0.234119]
["OxaloacetateM",5,0.234467]
["Tetrahydrofolyl-[Glu](n)",3,0.23512]
["GTP",9,0.239873]
["1,3-beta-D-Glucan",7,0.242458]
["CDPcholine",2,0.248923]
["dGDP",3,0.249084]
["ProtoporphyrinM",2,0.250751]
["Acyl-CoA",5,0.256049]
["dADP",4,0.261953]
["AACCOAm",1,0.262785]
["5,10-MethylenetetrahydrofolateM",5,0.264712]
["Tetradecanoyl-CoA",1,0.265155]
["Glycylpeptide",1,0.265155]
["N-Tetradecanoylglycylpeptide",1,0.265155]
["GDP",16,0.266315]
["Malate",8,0.267053]
["AMPM",6,0.270246]
["2-Oxoglutarate",21,0.270335]
["2-Oxo-3-hydroxy-4-phosphobutanoate",1,0.27214700000000003]
["ATTxt",1,0.273032]
["SuccinateM",5,0.276731]
["3-(Imidazol-4-yl)-2-oxopropyl phosphate",2,0.280165]
["Malonyl-[acyl-carrier protein]",2,0.280498]
["Acyl-[acyl-carrier protein]",2,0.280498]
["4-Guanidino-butanamide",2,0.281706]
["4-Guanidino-butanoate",2,0.281706]
["Glycerone phosphate",7,0.28697]
["dGTP",1,0.287073]
["dTTP",1,0.287073]
["L-Glutamine",20,0.287404]
["2-Nonaprenylphenol",1,0.287642]
["Thiamin",4,0.289608]
["AcetateM",2,0.294329]
["2-Phenylacetamide",1,0.295343]
["Phenylacetic acid",1,0.295343]
["Indole-3-acetamide",1,0.295343]
["Indole-3-acetate",1,0.295343]
["S-Adenosyl-L-homocysteine",10,0.295928]
["UMP",4,0.304887]
["5-(2-Hydroxyethyl)-4-methylthiazole",1,0.305259]
["4-Methyl-5-(2-phosphoethyl)-thiazole",1,0.305259]
["Thiamin monophosphate",1,0.305259]
["CMP",6,0.307494]
["tRNA(His)",1,0.308918]
["L-Histidyl-tRNA(His)",1,0.308918]
["tRNA(Lys)",1,0.309319]
["L-lysyl-tRNA(Lys)",1,0.309319]
["Malonyl-CoA",2,0.314108]
["3-Phospho-D-glyceroyl phosphate",5,0.318651]
["1L-myo-Inositol 1-phosphate",2,0.320667]
["beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol",7,0.323405]
["(\"alpha\"-D-mannosyl)(,2)-\"beta\"-D-mannosyl-diacetylchitobiosyldiphosphod olichol",7,0.323405]
["dUDP",3,0.323726]
["ADP",82,0.32385]
["ItaconateM",1,0.324393]
["Itaconyl-CoAM",1,0.324393]
["alpha,alpha'-Trehalose 6-phosphate",4,0.324915]
["Ferricytochrome cM",5,0.330523]
["Ferrocytochrome cM",5,0.330523]
["5-Methyltetrahydropteroyltri-L-glutamate",1,0.330679]
["Tetrahydropteroyltri-L-glutamate",1,0.330679]
["L-Glutamate",43,0.335666]
["(R)-Pantoate",2,0.338487]
["Intermediate_Methylzymosterol_I",2,0.339723]
["Intermediate_Zymosterol_I",2,0.339723]
["Ergosta-5,7,22,24(28)-tetraenol",2,0.339799]
["ACxt",1,0.341544]
["5-AminolevulinateM",1,0.346287]
["Porphobilinogen",2,0.346616]
["Nalpha-Acetylpeptide",2,0.347812]
["Adenylylsulfate",3,0.348098]
["L-Homoserine",3,0.348645]
["Inosine",2,0.349162]
["Deoxyadenosine",2,0.349162]
["Deoxyinosine",2,0.349162]
["(S)-LactateM",2,0.3492]
["Guanosine",2,0.352802]
["L-Citrulline",2,0.355477]
["dATP",2,0.358036]
["L-Glutamyl-tRNA(Glu)M",1,0.359623]
["Pyridine-2,3-dicarboxylate",1,0.363208]
["Pyridine-2,3-dicarboxylateM",1,0.363208]
["2-Oxobutanoate",3,0.36388]
["alpha,alpha-Trehalose",4,0.368957]
["D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate",2,0.369842]
["ORNxt",2,0.370127]
["GLxt",1,0.370793]
["L-Aspartate",14,0.370843]
["Oxidized glutathione",4,0.374992]
["D-4'-Phosphopantothenate",1,0.375319]
["N-Carbamoyl-L-aspartate",2,0.377526]
["Kxt",1,0.377902]
["Potassium",1,0.377902]
["1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole",2,0.37985]
["3-Methyl-2-oxobutanoate",1,0.385115]
["Ethanol",5,0.38516]
["NADHM",14,0.386892]
["D-Ribulose 5-phosphate",4,0.387865]
["Coproporphyrinogen",2,0.390129]
["L-ThreonineM",1,0.392776]
["URAxt",1,0.39737]
["Acetate",11,0.401054]
["CoAM",12,0.402484]
["L-OrnithineM",2,0.402755]
["Pseudouridine 5'-phosphate",4,0.404106]
["Allantoate",3,0.405001]
["L-Asparaginyl-tRNA(Asn)M",1,0.407092]
["O-AcetylcarnitineM",2,0.40993]
["CarnitineM",2,0.40993]
["NAD+",45,0.412775]
["MALxt",1,0.420619]
["Glyoxylate",6,0.4219]
["1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide",4,0.424319]
["L-AlanineM",1,0.42614]
["Uracil",8,0.430981]
["CHOxt",1,0.434556]
["THMxt",3,0.434889]
["Phytosphingosine",3,0.436277]
["C16_aldehydes",1,0.440265]
["L-Histidinol phosphate",2,0.443801]
["trans,trans-Farnesyl diphosphate",2,0.444228]
["Adenine",12,0.444471]
["Homocysteine",7,0.444773]
["Phenylpyruvate",2,0.445754]
["Choline phosphate",2,0.447892]
["URIxt",1,0.454137]
["L-Cystathionine",3,0.457479]
["alpha-D-Mannose",15,0.458407]
["Sulfate",5,0.458806]
["Carbamoyl phosphate",3,0.463649]
["Phytosphingosine 1-phosphate",2,0.465165]
["GTPM",1,0.467752]
["GDPM",1,0.467752]
["ITPM",1,0.467752]
["IDPM",1,0.467752]
["D-Ribose 5-phosphate",18,0.47007]
["ATPM",19,0.47048]
["D-Galactose",8,0.471955]
["D-Fructose",14,0.472304]
["IsocitrateM",5,0.47487]
["D-Ribose 1-phosphate",3,0.476767]
["Dethiobiotin",2,0.482416]
["O-Succinyl-L-homoserine",1,0.486858]
["5-Phospho-alpha-D-ribose 1-diphosphate",17,0.486958]
["(R)-Pantothenate",3,0.492365]
["AcetaldehydeM",3,0.492782]
["sn-Glycerol 3-phosphateM",1,0.49307]
["PhosphatidylglycerophosphateM",1,0.49307]
["ASNxt",4,0.493575]
["GLNxt",4,0.493575]
["D-Gal alpha 1->6D-Glucose",1,0.493705]
["beta-D-Glucose 6-phosphate",2,0.495461]
["3-Isopropylmalate",1,0.49658]
["2-Isopropylmaleate",1,0.49658]
["UTP",8,0.497723]
["Methanethiol",1,0.498062]
["3-Indoleacetonitrile",1,0.4991]
["Indoleacetate",1,0.4991]
["alpha-Aminopropiononitrile",1,0.4991]
["gamma-Amino-gamma-cyanobutanoate",1,0.4991]
["2-OxobutanoateM",2,0.499923]
["Hydrogen sulfide",4,0.50134]
["Sulfite",3,0.501366]
["O-Acetylcarnitine",2,0.505928]
["HomoisocitrateM",2,0.506522]
["2-Amino-3-carboxymuconate semialdehyde",1,0.506592]
["GMP",4,0.511621]
["Acyl-sn-glycerol 3-phosphate",1,0.513047]
["SUCxt",1,0.51358]
["L-Ornithine",7,0.513633]
["But-1-ene-1,2,4-tricarboxylateM",1,0.517785]
["dGMP",1,0.518815]
["OxaloglutarateM",3,0.520489]
["L-Asparagine",8,0.5209]
["2-OxoglutarateM",10,0.525623]
["Riboflavin",2,0.526337]
["Cys-Gly",1,0.527629]
["R-S-Alanylglycine",1,0.527629]
["3-Dehydroquinate",1,0.528665]
["3-Dehydroshikimate",1,0.528665]
["Shikimate",1,0.528665]
["Shikimate 3-phosphate",1,0.528665]
["SLFxt",3,0.530025]
["Oxaloglutarate",2,0.53111]
["HYXN",3,0.534663]
["CitrateM",5,0.537305]
["MANxt",11,0.537534]
["Peptide",3,0.538746]
["FRUxt",12,0.539921]
["Diacylglycerol",4,0.540795]
["beta-Alanine",1,0.541752]
["Anthranilate",4,0.542007]
["3-Phosphonooxypyruvate",3,0.543907]
["FumarateM",4,0.544516]
["Mannose-inositol-P-ceramide",3,0.544997]
["HO-M",1,0.550098]
["GlycineM",4,0.552108]
["(-)-Ureidoglycolate",2,0.562141]
["2-DehydropantoateM",1,0.563314]
["(R)-PantoateM",1,0.563314]
["SERxt",5,0.563493]
["2-Hydroxybutane-1,2,4-tricarboxylate",2,0.56417]
["Indoleglycerol phosphate",1,0.566369]
["N-(L-Arginino)succinate",2,0.566652]
["Thymidine",1,0.569666]
["Deoxy-ribose 1-phosphate",1,0.569666]
["Thymine",1,0.569666]
["Deoxyguanosine",1,0.569666]
["Xanthosine",1,0.569666]
["AdenonsineM",1,0.569666]
["AdenineM",1,0.569666]
["alpha-D-Ribose 1-phosphateM",1,0.569666]
["GuanosineM",1,0.569666]
["GuanineM",1,0.569666]
["Squalene",2,0.570033]
["PNTOxt",1,0.570962]
["Ceramide-2",1,0.571761]
["L-Arginine",7,0.573841]
["(S)-1-Pyrroline-5-carboxylate",1,0.574404]
["L-1-Pyrroline-3-hydroxy-5-carboxylate",1,0.574404]
["trans-4-Hydroxy-L-proline",1,0.574404]
["Succinate semialdehyde",2,0.577028]
["Protoporphyrinogen IX",1,0.57704]
["L-AspartateM",2,0.577671]
["CMPM",3,0.57771]
["METxt",7,0.578083]
["Isopentenyl diphosphate",3,0.578842]
["Prephenate",3,0.580475]
["L-Serine",14,0.581425]
["ADPM",13,0.581466]
["L-Methionine",13,0.581503]
["N-Acetyl-L-glutamateM",2,0.581977]
["PyruvateM",6,0.584661]
["Formaldehyde",1,0.587808]
["GLCxt",14,0.588994]
["(R)-Mevalonate",3,0.591151]
["Xanthine",2,0.593363]
["Acetaldehyde",12,0.594733]
["beta-D-Glucose",3,0.596985]
["Phosphatidylethanolamine",3,0.598273]
["(R)-5-Diphosphomevalonate",2,0.599148]
["alpha-D-Glucose",28,0.600076]
["Choline",2,0.600348]
["MMETxt",1,0.601023]
["S-Methylmethionine",1,0.601023]
["GLACxt",5,0.603801]
["Dimethylallyl diphosphate",2,0.60644]
["Methylglyoxal",1,0.611842]
["Orotate",3,0.614424]
["Carnitine",3,0.614549]
["Oxaloacetate",8,0.616522]
["PHExt",5,0.61742]
["2-Aceto-2-hydroxy butyrateM",2,0.619789]
["2-AcetolactateM",2,0.619789]
["Chitosan",2,0.620044]
["CTP",8,0.625193]
["HemeM",1,0.625868]
["5'-Phosphoribosylglycinamide",2,0.630649]
["UbiquinolM",11,0.631362]
["CDPdiacylglycerol",3,0.632041]
["Myristic acid",1,0.63498]
["Palmitate",1,0.63498]
["Stearate",1,0.63498]
["(R)-3-Hydroxy-3-methyl-2-oxobutanoateM",2,0.635544]
["(R)-2,3-dihydroxy-3-methylbutanoateM",2,0.635544]
["L-Phenylalanine",6,0.635805]
["NMNm",1,0.637865]
["Allantoin",2,0.638307]
["IMP",11,0.638622]
["C100ACPm",1,0.640425]
["Dodecanoyl-[acyl-carrier protein]M",1,0.640425]
["Myristoyl-[acyl-carrier protein]M",1,0.640425]
["Tetradecenoyl-[acyl-carrier protein]M",1,0.640425]
["Hexadecanoyl-[acp]M",1,0.640425]
["Palmitoyl-[acyl-carrier protein]M",1,0.640425]
["Stearoyl-[acyl-carrier protein]M",1,0.640425]
["Oleoyl-[acyl-carrier protein]M",1,0.640425]
["Linolenoyl-[acyl-carrier protein]M",1,0.640425]
["Oxygen",16,0.641478]
["Spermidine",3,0.643539]
["O-Acetyl-L-homoserine",2,0.644537]
["(3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]",1,0.645455]
["Hexadecenoyl-[acp]",1,0.645455]
["Acyl-[acyl-carrier-protein]",1,0.645455]
["2,3-Dehydroacyl-[acyl-carrier-protein]",1,0.645455]
["L-Histidine",7,0.646495]
["L-2-Aminoadipate 6-semialdehyde",2,0.64851]
["Inositol phosphorylceramide",3,0.648595]
["ATNxt",1,0.648658]
["L-LysineM",1,0.650458]
["tRNA(Lys)M",1,0.650458]
["L-lysyl-tRNA(Lys)M",1,0.650458]
["3-Hydroxyanthranilate",2,0.654316]
["L-2-Aminoadipate",1,0.654618]
["N-Acetyl-L-glutamate 5-phosphateM",1,0.655457]
["alpha-D-Glucose 6-phosphate",11,0.655863]
["2-(3-Carboxy-3-aminopropyl)-L-histidine",1,0.656043]
["2-[3-Carboxy-3-(methylammonio)propyl]-L-histidine",1,0.656043]
["OrthophosphateM",13,0.65649]
["FMN",4,0.658916]
["L-Tryptophan",7,0.659478]
["NADH",41,0.664486]
["Glycerone",2,0.668761]
["Fumarate",5,0.668844]
["N6-(L-1,3-Dicarboxypropyl)-L-lysine",2,0.669459]
["1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide",2,0.672747]
["L-Cysteine",10,0.673408]
["N1-(5-Phospho-D-ribosyl)-AMP",1,0.67414]
["N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5\"-phospho-D-ribosyl)-4-imidazolecarboxamide",2,0.674645]
["2-Hydroxybutane-1,2,4-tricarboxylateM",1,0.674897]
["ASPxt",3,0.676739]
["Uridine",3,0.677898]
["Acetyl-CoAM",8,0.678228]
["UREAxt",1,0.681712]
["CARxt",1,0.685365]
["Inositol-mannose-P-inositol-P-ceramide",1,0.685626]
["LipoamideM",1,0.686968]
["S-AminomethyldihydrolipoylproteinM",1,0.686968]
["Phosphoenolpyruvate",10,0.68815]
["Putrescine",2,0.688991]
["N2-Acetyl-L-ornithineM",2,0.689525]
["TetrahydrofolateM",5,0.689646]
["THRxt",4,0.69138]
["Cytosine",5,0.692878]
["tRNA",1,0.693909]
["L-Asparaginyl-tRNA(Asn)",1,0.693909]
["FAD",2,0.695872]
["tRNAM",2,0.697018]
["3-Carboxy-4-methyl-2-oxopentanoateM",1,0.698724]
["L-LeucineM",1,0.698724]
["L-IsoleucineM",1,0.698724]
["CYSxt",6,0.701846]
["ARGxt",3,0.703555]
["O-Phospho-4-hydroxy-L-threonine",2,0.709793]
["L-Lysine",4,0.709898]
["D-Glyceraldehyde 3-phosphate",10,0.71034]
["D-Ribose",2,0.711789]
["Guanine",7,0.712693]
["L-Kynurenine",2,0.71462]
["3-Hydroxykynurenine",2,0.71462]
["Tetrahydrofolate",11,0.716795]
["Urea-1-carboxylate",1,0.721334]
["CO2M",13,0.725591]
["3-Methyl-2-oxobutanoateM",2,0.726451]
["GLYxt",4,0.730152]
["Glycerol",5,0.73352]
["Urea",4,0.736221]
["(3S)-3-Hydroxyacyl-CoA",1,0.737292]
["5-Phospho-alpha-D-ribose 1-diphosphateM",2,0.739397]
["Cytidine",2,0.741087]
["GLUxt",5,0.743607]
["CYTSxt",4,0.745287]
["ADxt",4,0.745287]
["GNxt",4,0.745287]
["L-Proline",3,0.747967]
["sn-Glycerol 3-phosphate",6,0.749987]
["PROxt",2,0.753385]
["(R)-LactateM",2,0.754606]
["4-amino-4-deoxychorismate",1,0.758964]
["UDPglucose",12,0.760668]
["DIPEPxt",1,0.7646]
["Dipeptide",1,0.7646]
["OPEPxt",1,0.7646]
["Oligopeptide",1,0.7646]
["PEPTxt",1,0.7646]
["Nicotinate D-ribonucleotide",3,0.766631]
["Nicotinate D-ribonucleotideM",3,0.766631]
["L-Threonine",7,0.76744]
["EthanolM",1,0.768176]
["P1,P4-Bis(5'-guanosyl) tetraphosphate",1,0.768654]
["(R)-S-LactoylglutathioneM",1,0.770927]
["GlutathioneM",1,0.770927]
["(R)-5-Phosphomevalonate",2,0.774141]
["ALAxt",5,0.774946]
["3-Dehydrosphinganine",3,0.775125]
["Orthophosphate",69,0.782683]
["L-Histidinol",2,0.782802]
["5,10-MethenyltetrahydrofolateM",1,0.785496]
["FormateM",1,0.785496]
["Palmitoyl-CoA",2,0.78613]
["6-Phospho-D-gluconate",6,0.786601]
["LYSxt",2,0.786668]
["(S)-Dihydroorotate",2,0.786809]
["Ceramide-3",2,0.78784]
["Dolichyl phosphate",8,0.787898]
["3-Oxoacyl-CoA",2,0.788001]
["GlutamateM",7,0.791286]
["L-Leucine",7,0.79392]
["Ubiquinone-9M",10,0.801916]
["PhosphatidylserineM",2,0.80333]
["N-Acetyl-L-glutamate 5-semialdehydeM",2,0.803376]
["S-Adenosyl-L-methionine",15,0.805197]
["Geranyl diphosphate",1,0.807057]
["beta-D-Fructose 6-phosphate",15,0.807649]
["N-(5-Phospho-D-ribosyl)anthranilate",2,0.808756]
["S-Adenosylmethioninamine",2,0.809293]
["Ergosta-5,7,24(28)-trienol",2,0.812518]
["1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate",3,0.813598]
["H2O2",7,0.81429]
["Pyruvate",15,0.814853]
["3',5'-Cyclic dAMP",1,0.817126]
["dAMP",1,0.817126]
["3',5'-Cyclic IMP",1,0.817126]
["3',5'-Cyclic GMP",1,0.817126]
["3',5'-Cyclic CMP",1,0.817126]
["N1-(5-Phospho-D-ribosyl)-ATP",2,0.821469]
["Deoxyuridine",2,0.822026]
["L-Glutamate 5-semialdehydeM",1,0.830465]
["L-TryptophanM",1,0.832484]
["L-Tryptophanyl-tRNA(Trp)M",1,0.832484]
["Phosphatidate",4,0.835685]
["D-Mannose 6-phosphate",5,0.835922]
["PyrophosphateM",10,0.836714]
["TRPxt",5,0.837038]
["Biotin",3,0.83756]
["CDPdiacylglycerolM",4,0.840061]
["L-Alanine",10,0.842291]
["LEUxt",6,0.842505]
["Nicotinamide",1,0.842675]
["NicotinamideM",1,0.842675]
["D-Galactose 1-phosphate",2,0.844764]
["NH3xt",3,0.846854]
["BTxt",1,0.848112]
["L-Methionyl-tRNAM",1,0.848543]
["N-Formylmethionyl-tRNAM",1,0.848543]
["LACxt",1,0.853686]
["PYRxt",1,0.853686]
["O-Phospho-L-homoserine",2,0.854041]
["HISxt",4,0.854555]
["Chitin",5,0.85487]
["Spermine",1,0.857258]
["3-(4-Hydroxyphenyl)pyruvate",5,0.858643]
["TYRxt",6,0.861145]
["FMNM",2,0.862112]
["D-Glucono-1,5-lactone 6-phosphate",5,0.864522]
["Formate",6,0.867023]
["Glycine",10,0.868933]
["5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide",2,0.86986]
["BIOxt",1,0.869889]
["Deoxycytidine",1,0.870634]
["Phosphatidylcholine",2,0.872578]
["Chorismate",5,0.874057]
["Mannan",6,0.874857]
["Diacylglycerol pyrophosphate",1,0.878686]
["(R)-S-Lactoylglutathione",2,0.880971]
["L-Tyrosine",10,0.887321]
["Dolichyl beta-D-mannosyl phosphate",7,0.887821]
["Lanosterol",2,0.893333]
["L-Isoleucine",6,0.894871]
["L-Valine",6,0.894871]
["Dihydroneopterin phosphate",1,0.897524]
["UDP-D-galactose",2,0.899396]
["2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate",3,0.9005]
["SAMxt",1,0.900724]
["10-FormyltetrahydrofolateM",2,0.901151]
["5-O-(1-Carboxyvinyl)-3-phosphoshikimate",2,0.901764]
["1-Phosphatidyl-D-myo-inositol",8,0.904464]
["5'-Methylthioadenosine",2,0.907143]
["3',5'-Cyclic AMP",3,0.908071]
["Glutathione",10,0.911154]
["Acyl-[acyl-carrier protein]M",2,0.91181]
["Malonyl-[acyl-carrier protein]M",2,0.91181]
["Acyl-carrier proteinM",2,0.91181]
["4-Hydroxy-L-threonine",1,0.917365]
["D-Glucosamine 1-phosphate",1,0.917395]
["Sedoheptulose 7-phosphate",5,0.922891]
["RiboflavinM",1,0.924026]
["D-Tagatose 6-phosphate",1,0.926573]
["D-Tagatose 1,6-bisphosphate",1,0.926573]
["Sedoheptulose 1,7-bisphosphate",1,0.926573]
["P1,P4-Bis(5'-adenosyl) tetraphosphate",2,0.928075]
["ALAVxt",1,0.928822]
["Deoxyribose",1,0.933149]
["2-Deoxy-D-ribose 5-phosphate",1,0.933149]
["ILExt",5,0.933552]
["VALxt",5,0.933552]
["5-Aminolevulinate",2,0.938427]
["3OACPm",1,0.939643]
["S-Formylglutathione",2,0.940938]
["PhosphatidylglycerolM",1,0.943687]
["CardiolipinM",1,0.943687]
["D-Erythrose 4-phosphate",6,0.94375]
["Nicotinate",2,0.9452]
["NicotinateM",2,0.9452]
["10-Formyltetrahydrofolate",4,0.948576]
["Pyridoxine",1,0.949152]
["Pyridoxine phosphate",1,0.949152]
["Pyridoxamine",1,0.949152]
["Pyridoxamine phosphate",1,0.949152]
["Pyridoxal",1,0.949152]
["Pyridoxal phosphate",1,0.949152]
["PhosphatidateM",1,0.950427]
["CTPM",1,0.950427]
["Episterol",2,0.950452]
["5'-Phosphoribosyl-N-formylglycinamide",2,0.952637]
["UDP",15,0.952766]
["(R)-2-OxoisovalerateM",2,0.953985]
["D-Xylose-5-phosphate",4,0.956902]
["(R)-Lactate",2,0.957568]
["UDP-N-acetyl-D-galactosamine",4,0.958385]
["D-Xylulose",1,0.958756]
["7,8-Diaminononanoate",2,0.961679]
["H+EXT",46,0.964674]
["Phosphatidyl-N-dimethylethanolamine",1,0.968501]
["1-Phosphatidyl-1D-myo-inositol 3-phosphate",3,0.973444]
["D-myo-inositol 1,4,5-trisphosphate",1,0.974959]
["Maltose",4,0.975507]
["gamma-L-Glutamyl-L-cysteine",2,0.976774]
["Glycogen",4,0.977675]
["2-IsopropylmalateM",1,0.979902]
["N-Acetyl-D-glucosamine 1-phosphate",2,0.980538]
["L-Glutamate 5-semialdehyde",2,0.980955]
["4-Aminobutanoate",4,0.982125]
["GABAxt",2,0.982761]
["8-Amino-7-oxononanoate",1,0.982817]
["S-Adenosyl-4-methylthio-2-oxobutanoate",1,0.982817]
["alpha-D-Glutamyl phosphate",2,0.983592]
["1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate",1,0.985112]
["beta-D-Fructose 1,6-bisphosphate",4,0.988381]
["PIxt",1,0.99082]
["PhosphatidylethanolamineM",1,0.992599]
["Phosphatidyl-N-methylethanolamine",2,0.994964]
["(S)-2,3-Epoxysqualene",2,0.998105]